id sid tid token lemma pos cord-005646-xhx9pzhj 1 1 key key JJ cord-005646-xhx9pzhj 2 1 : : : cord-005646-xhx9pzhj 2 2 cord-005646-xhx9pzhj cord-005646-xhx9pzhj NNP cord-005646-xhx9pzhj 2 3 authors author NNS cord-005646-xhx9pzhj 2 4 : : : cord-005646-xhx9pzhj 3 1 nan nan NNP cord-005646-xhx9pzhj 3 2 title title NN cord-005646-xhx9pzhj 3 3 : : : cord-005646-xhx9pzhj 3 4 2nd 2nd NNP cord-005646-xhx9pzhj 3 5 World World NNP cord-005646-xhx9pzhj 3 6 Congress Congress NNP cord-005646-xhx9pzhj 3 7 on on IN cord-005646-xhx9pzhj 3 8 Pediatric Pediatric NNP cord-005646-xhx9pzhj 3 9 Intensive Intensive NNP cord-005646-xhx9pzhj 3 10 Care Care NNP cord-005646-xhx9pzhj 3 11 1996 1996 CD cord-005646-xhx9pzhj 3 12 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 3 13 , , , cord-005646-xhx9pzhj 3 14 The the DT cord-005646-xhx9pzhj 3 15 Netherlands Netherlands NNP cord-005646-xhx9pzhj 3 16 , , , cord-005646-xhx9pzhj 4 1 23–26 23–26 CD cord-005646-xhx9pzhj 4 2 June June NNP cord-005646-xhx9pzhj 4 3 1996 1996 CD cord-005646-xhx9pzhj 5 1 Abstracts abstract NNS cord-005646-xhx9pzhj 5 2 of of IN cord-005646-xhx9pzhj 5 3 Oral Oral NNP cord-005646-xhx9pzhj 5 4 Presentations Presentations NNPS cord-005646-xhx9pzhj 5 5 , , , cord-005646-xhx9pzhj 5 6 Posters Posters NNPS cord-005646-xhx9pzhj 5 7 and and CC cord-005646-xhx9pzhj 5 8 Nursing Nursing NNP cord-005646-xhx9pzhj 5 9 Programme Programme NNP cord-005646-xhx9pzhj 5 10 date date NN cord-005646-xhx9pzhj 5 11 : : : cord-005646-xhx9pzhj 5 12 1996 1996 CD cord-005646-xhx9pzhj 5 13 journal journal NN cord-005646-xhx9pzhj 5 14 : : : cord-005646-xhx9pzhj 6 1 Intensive intensive JJ cord-005646-xhx9pzhj 6 2 Care care NN cord-005646-xhx9pzhj 6 3 Med Med NNP cord-005646-xhx9pzhj 6 4 DOI doi NN cord-005646-xhx9pzhj 6 5 : : : cord-005646-xhx9pzhj 6 6 10.1007 10.1007 CD cord-005646-xhx9pzhj 6 7 / / SYM cord-005646-xhx9pzhj 6 8 bf02316512 bf02316512 NN cord-005646-xhx9pzhj 6 9 sha sha NNP cord-005646-xhx9pzhj 6 10 : : : cord-005646-xhx9pzhj 6 11 7d67e9230359eff642324861fb5776764a13d6f8 7d67e9230359eff642324861fb5776764a13d6f8 CD cord-005646-xhx9pzhj 6 12 doc_id doc_id CD cord-005646-xhx9pzhj 6 13 : : : cord-005646-xhx9pzhj 6 14 5646 5646 CD cord-005646-xhx9pzhj 6 15 cord_uid cord_uid NNS cord-005646-xhx9pzhj 6 16 : : : cord-005646-xhx9pzhj 7 1 xhx9pzhj xhx9pzhj NNP cord-005646-xhx9pzhj 7 2 nan nan NNP cord-005646-xhx9pzhj 8 1 We -PRON- PRP cord-005646-xhx9pzhj 8 2 present present VBP cord-005646-xhx9pzhj 8 3 the the DT cord-005646-xhx9pzhj 8 4 results result NNS cord-005646-xhx9pzhj 8 5 of of IN cord-005646-xhx9pzhj 8 6 a a DT cord-005646-xhx9pzhj 8 7 prospective prospective JJ cord-005646-xhx9pzhj 8 8 population population NN cord-005646-xhx9pzhj 8 9 - - HYPH cord-005646-xhx9pzhj 8 10 based base VBN cord-005646-xhx9pzhj 8 11 audit audit NN cord-005646-xhx9pzhj 8 12 of of IN cord-005646-xhx9pzhj 8 13 paediatric paediatric JJ cord-005646-xhx9pzhj 8 14 intensive intensive JJ cord-005646-xhx9pzhj 8 15 care care NN cord-005646-xhx9pzhj 8 16 activity activity NN cord-005646-xhx9pzhj 8 17 in in IN cord-005646-xhx9pzhj 8 18 two two CD cord-005646-xhx9pzhj 8 19 comparable comparable JJ cord-005646-xhx9pzhj 8 20 communities community NNS cord-005646-xhx9pzhj 8 21 with with IN cord-005646-xhx9pzhj 8 22 markedly markedly RB cord-005646-xhx9pzhj 8 23 different different JJ cord-005646-xhx9pzhj 8 24 delivery delivery NN cord-005646-xhx9pzhj 8 25 systems system NNS cord-005646-xhx9pzhj 8 26 . . . cord-005646-xhx9pzhj 9 1 In in IN cord-005646-xhx9pzhj 9 2 the the DT cord-005646-xhx9pzhj 9 3 Trent Trent NNP cord-005646-xhx9pzhj 9 4 region region NN cord-005646-xhx9pzhj 9 5 of of IN cord-005646-xhx9pzhj 9 6 the the DT cord-005646-xhx9pzhj 9 7 UK UK NNP cord-005646-xhx9pzhj 9 8 ( ( -LRB- cord-005646-xhx9pzhj 9 9 4.2 4.2 CD cord-005646-xhx9pzhj 9 10 million million CD cord-005646-xhx9pzhj 9 11 people people NNS cord-005646-xhx9pzhj 9 12 ) ) -RRB- cord-005646-xhx9pzhj 9 13 , , , cord-005646-xhx9pzhj 9 14 children child NNS cord-005646-xhx9pzhj 9 15 receive receive VBP cord-005646-xhx9pzhj 9 16 intensive intensive JJ cord-005646-xhx9pzhj 9 17 care care NN cord-005646-xhx9pzhj 9 18 largely largely RB cord-005646-xhx9pzhj 9 19 without without IN cord-005646-xhx9pzhj 9 20 the the DT cord-005646-xhx9pzhj 9 21 supervision supervision NN cord-005646-xhx9pzhj 9 22 of of IN cord-005646-xhx9pzhj 9 23 a a DT cord-005646-xhx9pzhj 9 24 paediatric paediatric JJ cord-005646-xhx9pzhj 9 25 intensivist intensivist NN cord-005646-xhx9pzhj 9 26 in in IN cord-005646-xhx9pzhj 9 27 a a DT cord-005646-xhx9pzhj 9 28 variety variety NN cord-005646-xhx9pzhj 9 29 of of IN cord-005646-xhx9pzhj 9 30 hospitals hospital NNS cord-005646-xhx9pzhj 9 31 , , , cord-005646-xhx9pzhj 9 32 few few JJ cord-005646-xhx9pzhj 9 33 of of IN cord-005646-xhx9pzhj 9 34 which which WDT cord-005646-xhx9pzhj 9 35 have have VBP cord-005646-xhx9pzhj 9 36 designated designate VBN cord-005646-xhx9pzhj 9 37 Paediatric Paediatric NNP cord-005646-xhx9pzhj 9 38 Intensive Intensive NNP cord-005646-xhx9pzhj 9 39 Care Care NNP cord-005646-xhx9pzhj 9 40 Units Units NNPS cord-005646-xhx9pzhj 9 41 ( ( -LRB- cord-005646-xhx9pzhj 9 42 PICUs PICUs NNP cord-005646-xhx9pzhj 9 43 ) ) -RRB- cord-005646-xhx9pzhj 9 44 . . . cord-005646-xhx9pzhj 10 1 Critically critically RB cord-005646-xhx9pzhj 10 2 ill ill JJ cord-005646-xhx9pzhj 10 3 children child NNS cord-005646-xhx9pzhj 10 4 otherwise otherwise RB cord-005646-xhx9pzhj 10 5 receive receive VBP cord-005646-xhx9pzhj 10 6 intensive intensive JJ cord-005646-xhx9pzhj 10 7 care care NN cord-005646-xhx9pzhj 10 8 in in IN cord-005646-xhx9pzhj 10 9 children child NNS cord-005646-xhx9pzhj 10 10 's 's POS cord-005646-xhx9pzhj 10 11 wards ward NNS cord-005646-xhx9pzhj 10 12 , , , cord-005646-xhx9pzhj 10 13 special special JJ cord-005646-xhx9pzhj 10 14 care care NN cord-005646-xhx9pzhj 10 15 baby baby NN cord-005646-xhx9pzhj 10 16 units unit NNS cord-005646-xhx9pzhj 10 17 ( ( -LRB- cord-005646-xhx9pzhj 10 18 SCBUs SCBUs NNP cord-005646-xhx9pzhj 10 19 ) ) -RRB- cord-005646-xhx9pzhj 10 20 or or CC cord-005646-xhx9pzhj 10 21 adult adult NN cord-005646-xhx9pzhj 10 22 intensive intensive JJ cord-005646-xhx9pzhj 10 23 care care NN cord-005646-xhx9pzhj 10 24 units unit NNS cord-005646-xhx9pzhj 10 25 . . . cord-005646-xhx9pzhj 11 1 In in IN cord-005646-xhx9pzhj 11 2 the the DT cord-005646-xhx9pzhj 11 3 Australian australian JJ cord-005646-xhx9pzhj 11 4 State State NNP cord-005646-xhx9pzhj 11 5 of of IN cord-005646-xhx9pzhj 11 6 Victoria Victoria NNP cord-005646-xhx9pzhj 11 7 ( ( -LRB- cord-005646-xhx9pzhj 11 8 4.5 4.5 CD cord-005646-xhx9pzhj 11 9 million million CD cord-005646-xhx9pzhj 11 10 people people NNS cord-005646-xhx9pzhj 11 11 ) ) -RRB- cord-005646-xhx9pzhj 11 12 , , , cord-005646-xhx9pzhj 11 13 children child NNS cord-005646-xhx9pzhj 11 14 receive receive VBP cord-005646-xhx9pzhj 11 15 intensive intensive JJ cord-005646-xhx9pzhj 11 16 care care NN cord-005646-xhx9pzhj 11 17 almost almost RB cord-005646-xhx9pzhj 11 18 exclusively exclusively RB cord-005646-xhx9pzhj 11 19 in in IN cord-005646-xhx9pzhj 11 20 one one CD cord-005646-xhx9pzhj 11 21 centre centre NN cord-005646-xhx9pzhj 11 22 -a -a . cord-005646-xhx9pzhj 12 1 PICU PICU NNP cord-005646-xhx9pzhj 12 2 staffed staff VBN cord-005646-xhx9pzhj 12 3 by by IN cord-005646-xhx9pzhj 12 4 full full JJ cord-005646-xhx9pzhj 12 5 time time NN cord-005646-xhx9pzhj 12 6 paediatric paediatric JJ cord-005646-xhx9pzhj 12 7 intensivists intensivist NNS cord-005646-xhx9pzhj 12 8 . . . cord-005646-xhx9pzhj 13 1 The the DT cord-005646-xhx9pzhj 13 2 two two CD cord-005646-xhx9pzhj 13 3 regions region NNS cord-005646-xhx9pzhj 13 4 are be VBP cord-005646-xhx9pzhj 13 5 otherwise otherwise RB cord-005646-xhx9pzhj 13 6 demographically demographically RB cord-005646-xhx9pzhj 13 7 comparable comparable JJ cord-005646-xhx9pzhj 13 8 . . . cord-005646-xhx9pzhj 14 1 In in IN cord-005646-xhx9pzhj 14 2 both both DT cord-005646-xhx9pzhj 14 3 groups group NNS cord-005646-xhx9pzhj 14 4 , , , cord-005646-xhx9pzhj 14 5 data datum NNS cord-005646-xhx9pzhj 14 6 were be VBD cord-005646-xhx9pzhj 14 7 collected collect VBN cord-005646-xhx9pzhj 14 8 on on IN cord-005646-xhx9pzhj 14 9 all all DT cord-005646-xhx9pzhj 14 10 children child NNS cord-005646-xhx9pzhj 14 11 admitted admit VBD cord-005646-xhx9pzhj 14 12 to to IN cord-005646-xhx9pzhj 14 13 an an DT cord-005646-xhx9pzhj 14 14 intensive intensive JJ cord-005646-xhx9pzhj 14 15 care care NN cord-005646-xhx9pzhj 14 16 unit unit NN cord-005646-xhx9pzhj 14 17 between between IN cord-005646-xhx9pzhj 14 18 1/4/94 1/4/94 CD cord-005646-xhx9pzhj 14 19 and and CC cord-005646-xhx9pzhj 14 20 31/3/95 31/3/95 NN cord-005646-xhx9pzhj 14 21 and and CC cord-005646-xhx9pzhj 14 22 children child NNS cord-005646-xhx9pzhj 14 23 who who WP cord-005646-xhx9pzhj 14 24 received receive VBD cord-005646-xhx9pzhj 14 25 intensive intensive JJ cord-005646-xhx9pzhj 14 26 care care NN cord-005646-xhx9pzhj 14 27 ( ( -LRB- cord-005646-xhx9pzhj 14 28 defined define VBN cord-005646-xhx9pzhj 14 29 by by IN cord-005646-xhx9pzhj 14 30 levels level NNS cord-005646-xhx9pzhj 14 31 of of IN cord-005646-xhx9pzhj 14 32 intervention intervention NN cord-005646-xhx9pzhj 14 33 and and CC cord-005646-xhx9pzhj 14 34 nurse nurse NN cord-005646-xhx9pzhj 14 35 dependency dependency NN cord-005646-xhx9pzhj 14 36 ) ) -RRB- cord-005646-xhx9pzhj 14 37 in in IN cord-005646-xhx9pzhj 14 38 other other JJ cord-005646-xhx9pzhj 14 39 sites site NNS cord-005646-xhx9pzhj 14 40 during during IN cord-005646-xhx9pzhj 14 41 the the DT cord-005646-xhx9pzhj 14 42 same same JJ cord-005646-xhx9pzhj 14 43 period period NN cord-005646-xhx9pzhj 14 44 . . . cord-005646-xhx9pzhj 15 1 Values value NNS cord-005646-xhx9pzhj 15 2 of of IN cord-005646-xhx9pzhj 15 3 each each DT cord-005646-xhx9pzhj 15 4 variable variable NN cord-005646-xhx9pzhj 15 5 at at IN cord-005646-xhx9pzhj 15 6 first first JJ cord-005646-xhx9pzhj 15 7 contact contact NN cord-005646-xhx9pzhj 15 8 with with IN cord-005646-xhx9pzhj 15 9 the the DT cord-005646-xhx9pzhj 15 10 ICU ICU NNP cord-005646-xhx9pzhj 15 11 , , , cord-005646-xhx9pzhj 15 12 and and CC cord-005646-xhx9pzhj 15 13 the the DT cord-005646-xhx9pzhj 15 14 highest high JJS cord-005646-xhx9pzhj 15 15 and and CC cord-005646-xhx9pzhj 15 16 lowest low JJS cord-005646-xhx9pzhj 15 17 values value NNS cord-005646-xhx9pzhj 15 18 over over IN cord-005646-xhx9pzhj 15 19 the the DT cord-005646-xhx9pzhj 15 20 first first JJ cord-005646-xhx9pzhj 15 21 24 24 CD cord-005646-xhx9pzhj 15 22 hours hour NNS cord-005646-xhx9pzhj 15 23 were be VBD cord-005646-xhx9pzhj 15 24 recorded record VBN cord-005646-xhx9pzhj 15 25 . . . cord-005646-xhx9pzhj 16 1 The the DT cord-005646-xhx9pzhj 16 2 principal principal JJ cord-005646-xhx9pzhj 16 3 outcome outcome NN cord-005646-xhx9pzhj 16 4 was be VBD cord-005646-xhx9pzhj 16 5 survival survival NN cord-005646-xhx9pzhj 16 6 to to TO cord-005646-xhx9pzhj 16 7 discharge discharge VB cord-005646-xhx9pzhj 16 8 from from IN cord-005646-xhx9pzhj 16 9 the the DT cord-005646-xhx9pzhj 16 10 intensive intensive JJ cord-005646-xhx9pzhj 16 11 care care NN cord-005646-xhx9pzhj 16 12 unit unit NN cord-005646-xhx9pzhj 16 13 . . . cord-005646-xhx9pzhj 17 1 Severity severity NN cord-005646-xhx9pzhj 17 2 of of IN cord-005646-xhx9pzhj 17 3 illness illness NN cord-005646-xhx9pzhj 17 4 was be VBD cord-005646-xhx9pzhj 17 5 assessed assess VBN cord-005646-xhx9pzhj 17 6 using use VBG cord-005646-xhx9pzhj 17 7 PIM PIM NNP cord-005646-xhx9pzhj 17 8 ( ( -LRB- cord-005646-xhx9pzhj 17 9 Paediatric Paediatric NNP cord-005646-xhx9pzhj 17 10 Index Index NNP cord-005646-xhx9pzhj 17 11 of of IN cord-005646-xhx9pzhj 17 12 Mortality Mortality NNP cord-005646-xhx9pzhj 17 13 ) ) -RRB- cord-005646-xhx9pzhj 17 14 and and CC cord-005646-xhx9pzhj 17 15 PRISM PRISM NNP cord-005646-xhx9pzhj 17 16 . . . cord-005646-xhx9pzhj 18 1 Risk risk NN cord-005646-xhx9pzhj 18 2 - - HYPH cord-005646-xhx9pzhj 18 3 adjusted adjust VBN cord-005646-xhx9pzhj 18 4 mortality mortality NN cord-005646-xhx9pzhj 18 5 was be VBD cord-005646-xhx9pzhj 18 6 compared compare VBN cord-005646-xhx9pzhj 18 7 using use VBG cord-005646-xhx9pzhj 18 8 Flora Flora NNP cord-005646-xhx9pzhj 18 9 's 's POS cord-005646-xhx9pzhj 18 10 Z z NN cord-005646-xhx9pzhj 18 11 test test NN cord-005646-xhx9pzhj 18 12 and and CC cord-005646-xhx9pzhj 18 13 logistic logistic JJ cord-005646-xhx9pzhj 18 14 regression regression NN cord-005646-xhx9pzhj 18 15 . . . cord-005646-xhx9pzhj 19 1 The the DT cord-005646-xhx9pzhj 19 2 rate rate NN cord-005646-xhx9pzhj 19 3 of of IN cord-005646-xhx9pzhj 19 4 utilisation utilisation NN cord-005646-xhx9pzhj 19 5 of of IN cord-005646-xhx9pzhj 19 6 intensive intensive JJ cord-005646-xhx9pzhj 19 7 care care NN cord-005646-xhx9pzhj 19 8 ( ( -LRB- cord-005646-xhx9pzhj 19 9 > > NFP cord-005646-xhx9pzhj 19 10 1000 1000 CD cord-005646-xhx9pzhj 19 11 admissions admission NNS cord-005646-xhx9pzhj 19 12 in in IN cord-005646-xhx9pzhj 19 13 each each DT cord-005646-xhx9pzhj 19 14 region region NN cord-005646-xhx9pzhj 19 15 ) ) -RRB- cord-005646-xhx9pzhj 19 16 were be VBD cord-005646-xhx9pzhj 19 17 similar similar JJ cord-005646-xhx9pzhj 19 18 . . . cord-005646-xhx9pzhj 20 1 There there EX cord-005646-xhx9pzhj 20 2 was be VBD cord-005646-xhx9pzhj 20 3 some some DT cord-005646-xhx9pzhj 20 4 variation variation NN cord-005646-xhx9pzhj 20 5 in in IN cord-005646-xhx9pzhj 20 6 case case NN cord-005646-xhx9pzhj 20 7 mix mix NN cord-005646-xhx9pzhj 20 8 between between IN cord-005646-xhx9pzhj 20 9 the the DT cord-005646-xhx9pzhj 20 10 two two CD cord-005646-xhx9pzhj 20 11 groups group NNS cord-005646-xhx9pzhj 20 12 , , , cord-005646-xhx9pzhj 20 13 but but CC cord-005646-xhx9pzhj 20 14 crude crude JJ cord-005646-xhx9pzhj 20 15 mortality mortality NN cord-005646-xhx9pzhj 20 16 rates rate NNS cord-005646-xhx9pzhj 20 17 were be VBD cord-005646-xhx9pzhj 20 18 similar similar JJ cord-005646-xhx9pzhj 20 19 ( ( -LRB- cord-005646-xhx9pzhj 20 20 7.4 7.4 CD cord-005646-xhx9pzhj 20 21 % % NN cord-005646-xhx9pzhj 20 22 in in IN cord-005646-xhx9pzhj 20 23 Trent Trent NNP cord-005646-xhx9pzhj 20 24 and and CC cord-005646-xhx9pzhj 20 25 6.6 6.6 CD cord-005646-xhx9pzhj 20 26 % % NN cord-005646-xhx9pzhj 20 27 in in IN cord-005646-xhx9pzhj 20 28 Victoria Victoria NNP cord-005646-xhx9pzhj 20 29 ) ) -RRB- cord-005646-xhx9pzhj 20 30 . . . cord-005646-xhx9pzhj 21 1 However however RB cord-005646-xhx9pzhj 21 2 severity severity NN cord-005646-xhx9pzhj 21 3 corrected correct VBD cord-005646-xhx9pzhj 21 4 data datum NNS cord-005646-xhx9pzhj 21 5 and and CC cord-005646-xhx9pzhj 21 6 other other JJ cord-005646-xhx9pzhj 21 7 measures measure NNS cord-005646-xhx9pzhj 21 8 of of IN cord-005646-xhx9pzhj 21 9 PICU PICU NNP cord-005646-xhx9pzhj 21 10 performance performance NN cord-005646-xhx9pzhj 21 11 were be VBD cord-005646-xhx9pzhj 21 12 dramatically dramatically RB cord-005646-xhx9pzhj 21 13 better well JJR cord-005646-xhx9pzhj 21 14 in in IN cord-005646-xhx9pzhj 21 15 ' ' '' cord-005646-xhx9pzhj 21 16 the the DT cord-005646-xhx9pzhj 21 17 centralised centralised JJ cord-005646-xhx9pzhj 21 18 delivery delivery NN cord-005646-xhx9pzhj 21 19 system system NN cord-005646-xhx9pzhj 21 20 . . . cord-005646-xhx9pzhj 22 1 The the DT cord-005646-xhx9pzhj 22 2 substantial substantial JJ cord-005646-xhx9pzhj 22 3 excess excess JJ cord-005646-xhx9pzhj 22 4 mortality mortality NN cord-005646-xhx9pzhj 22 5 in in IN cord-005646-xhx9pzhj 22 6 the the DT cord-005646-xhx9pzhj 22 7 Trent Trent NNP cord-005646-xhx9pzhj 22 8 region region NN cord-005646-xhx9pzhj 22 9 provides provide VBZ cord-005646-xhx9pzhj 22 10 strong strong JJ cord-005646-xhx9pzhj 22 11 evidence evidence NN cord-005646-xhx9pzhj 22 12 for for IN cord-005646-xhx9pzhj 22 13 the the DT cord-005646-xhx9pzhj 22 14 benefits benefit NNS cord-005646-xhx9pzhj 22 15 of of IN cord-005646-xhx9pzhj 22 16 centralisation centralisation NN cord-005646-xhx9pzhj 22 17 of of IN cord-005646-xhx9pzhj 22 18 paediatric paediatric JJ cord-005646-xhx9pzhj 22 19 intensive intensive JJ cord-005646-xhx9pzhj 22 20 care care NN cord-005646-xhx9pzhj 22 21 services service NNS cord-005646-xhx9pzhj 22 22 . . . cord-005646-xhx9pzhj 23 1 There there EX cord-005646-xhx9pzhj 23 2 are be VBP cord-005646-xhx9pzhj 23 3 considerable considerable JJ cord-005646-xhx9pzhj 23 4 difficulties difficulty NNS cord-005646-xhx9pzhj 23 5 in in IN cord-005646-xhx9pzhj 23 6 evaluating evaluate VBG cord-005646-xhx9pzhj 23 7 the the DT cord-005646-xhx9pzhj 23 8 efficiency efficiency NN cord-005646-xhx9pzhj 23 9 and and CC cord-005646-xhx9pzhj 23 10 effectiveness effectiveness NN cord-005646-xhx9pzhj 23 11 oflcare oflcare NN cord-005646-xhx9pzhj 23 12 in in IN cord-005646-xhx9pzhj 23 13 children child NNS cord-005646-xhx9pzhj 23 14 presenting present VBG cord-005646-xhx9pzhj 23 15 with with IN cord-005646-xhx9pzhj 23 16 respiratory respiratory JJ cord-005646-xhx9pzhj 23 17 failure failure NN cord-005646-xhx9pzhj 23 18 during during IN cord-005646-xhx9pzhj 23 19 acute acute JJ cord-005646-xhx9pzhj 23 20 medical medical JJ cord-005646-xhx9pzhj 23 21 illness illness NN cord-005646-xhx9pzhj 23 22 . . . cord-005646-xhx9pzhj 24 1 Optimal optimal JJ cord-005646-xhx9pzhj 24 2 outcomes outcome NNS cord-005646-xhx9pzhj 24 3 for for IN cord-005646-xhx9pzhj 24 4 such such JJ cord-005646-xhx9pzhj 24 5 episodes episode NNS cord-005646-xhx9pzhj 24 6 include include VBP cord-005646-xhx9pzhj 24 7 survival survival NN cord-005646-xhx9pzhj 24 8 and and CC cord-005646-xhx9pzhj 24 9 the the DT cord-005646-xhx9pzhj 24 10 shortest short JJS cord-005646-xhx9pzhj 24 11 length length NN cord-005646-xhx9pzhj 24 12 of of IN cord-005646-xhx9pzhj 24 13 stay stay NN cord-005646-xhx9pzhj 24 14 ( ( -LRB- cord-005646-xhx9pzhj 24 15 LOS LOS NNP cord-005646-xhx9pzhj 24 16 ) ) -RRB- cord-005646-xhx9pzhj 24 17 in in IN cord-005646-xhx9pzhj 24 18 intensive intensive JJ cord-005646-xhx9pzhj 24 19 care care NN cord-005646-xhx9pzhj 24 20 with with IN cord-005646-xhx9pzhj 24 21 negligible negligible JJ cord-005646-xhx9pzhj 24 22 risk risk NN cord-005646-xhx9pzhj 24 23 of of IN cord-005646-xhx9pzhj 24 24 readmission readmission NN cord-005646-xhx9pzhj 24 25 . . . cord-005646-xhx9pzhj 25 1 We -PRON- PRP cord-005646-xhx9pzhj 25 2 have have VBP cord-005646-xhx9pzhj 25 3 tried try VBN cord-005646-xhx9pzhj 25 4 to to TO cord-005646-xhx9pzhj 25 5 determine determine VB cord-005646-xhx9pzhj 25 6 whether whether IN cord-005646-xhx9pzhj 25 7 or or CC cord-005646-xhx9pzhj 25 8 not not RB cord-005646-xhx9pzhj 25 9 the the DT cord-005646-xhx9pzhj 25 10 time time NN cord-005646-xhx9pzhj 25 11 course course NN cord-005646-xhx9pzhj 25 12 of of IN cord-005646-xhx9pzhj 25 13 acute acute JJ cord-005646-xhx9pzhj 25 14 severe severe JJ cord-005646-xhx9pzhj 25 15 medical medical JJ cord-005646-xhx9pzhj 25 16 illness illness NN cord-005646-xhx9pzhj 25 17 with with IN cord-005646-xhx9pzhj 25 18 respiratory respiratory JJ cord-005646-xhx9pzhj 25 19 failure failure NN cord-005646-xhx9pzhj 25 20 is be VBZ cord-005646-xhx9pzhj 25 21 predictable predictable JJ cord-005646-xhx9pzhj 25 22 . . . cord-005646-xhx9pzhj 26 1 Study study NN cord-005646-xhx9pzhj 26 2 I -PRON- PRP cord-005646-xhx9pzhj 26 3 ( ( -LRB- cord-005646-xhx9pzhj 26 4 n=1000 n=1000 NFP cord-005646-xhx9pzhj 26 5 ) ) -RRB- cord-005646-xhx9pzhj 26 6 : : : cord-005646-xhx9pzhj 27 1 A a DT cord-005646-xhx9pzhj 27 2 retrospective retrospective JJ cord-005646-xhx9pzhj 27 3 study study NN cord-005646-xhx9pzhj 27 4 of of IN cord-005646-xhx9pzhj 27 5 intubated intubate VBN cord-005646-xhx9pzhj 27 6 and and CC cord-005646-xhx9pzhj 27 7 mechanically mechanically RB cord-005646-xhx9pzhj 27 8 ventilated ventilate VBN cord-005646-xhx9pzhj 27 9 children child NNS cord-005646-xhx9pzhj 27 10 ( ( -LRB- cord-005646-xhx9pzhj 27 11 > > NFP cord-005646-xhx9pzhj 27 12 28 28 CD cord-005646-xhx9pzhj 27 13 days day NNS cord-005646-xhx9pzhj 27 14 , , , cord-005646-xhx9pzhj 27 15 < < XX cord-005646-xhx9pzhj 27 16 17 17 CD cord-005646-xhx9pzhj 27 17 years year NNS cord-005646-xhx9pzhj 27 18 ) ) -RRB- cord-005646-xhx9pzhj 27 19 with with IN cord-005646-xhx9pzhj 27 20 acute acute JJ cord-005646-xhx9pzhj 27 21 severe severe JJ cord-005646-xhx9pzhj 27 22 medical medical JJ cord-005646-xhx9pzhj 27 23 illness illness NN cord-005646-xhx9pzhj 27 24 . . . cord-005646-xhx9pzhj 28 1 Measures measure NNS cord-005646-xhx9pzhj 28 2 : : : cord-005646-xhx9pzhj 28 3 Diagnosis diagnosis NN cord-005646-xhx9pzhj 28 4 , , , cord-005646-xhx9pzhj 28 5 intensive intensive JJ cord-005646-xhx9pzhj 28 6 care care NN cord-005646-xhx9pzhj 28 7 LOS LOS NNP cord-005646-xhx9pzhj 28 8 in in IN cord-005646-xhx9pzhj 28 9 calender calender NN cord-005646-xhx9pzhj 28 10 days day NNS cord-005646-xhx9pzhj 28 11 , , , cord-005646-xhx9pzhj 28 12 and and CC cord-005646-xhx9pzhj 28 13 survival survival NN cord-005646-xhx9pzhj 28 14 . . . cord-005646-xhx9pzhj 29 1 Results result NNS cord-005646-xhx9pzhj 29 2 : : : cord-005646-xhx9pzhj 30 1 The the DT cord-005646-xhx9pzhj 30 2 underlying underlie VBG cord-005646-xhx9pzhj 30 3 diagnosis diagnosis NN cord-005646-xhx9pzhj 30 4 fell fall VBD cord-005646-xhx9pzhj 30 5 within within IN cord-005646-xhx9pzhj 30 6 one one CD cord-005646-xhx9pzhj 30 7 of of IN cord-005646-xhx9pzhj 30 8 three three CD cord-005646-xhx9pzhj 30 9 broad broad JJ cord-005646-xhx9pzhj 30 10 categories category NNS cord-005646-xhx9pzhj 30 11 : : : cord-005646-xhx9pzhj 30 12 respiratory respiratory JJ cord-005646-xhx9pzhj 30 13 disease disease NN cord-005646-xhx9pzhj 30 14 ( ( -LRB- cord-005646-xhx9pzhj 30 15 n=521 n=521 NNP cord-005646-xhx9pzhj 30 16 , , , cord-005646-xhx9pzhj 30 17 mortality mortality NN cord-005646-xhx9pzhj 30 18 19.2 19.2 CD cord-005646-xhx9pzhj 30 19 % % NN cord-005646-xhx9pzhj 30 20 ) ) -RRB- cord-005646-xhx9pzhj 30 21 , , , cord-005646-xhx9pzhj 30 22 central central JJ cord-005646-xhx9pzhj 30 23 nervous nervous JJ cord-005646-xhx9pzhj 30 24 system system NN cord-005646-xhx9pzhj 30 25 ( ( -LRB- cord-005646-xhx9pzhj 30 26 CNS CNS NNP cord-005646-xhx9pzhj 30 27 ) ) -RRB- cord-005646-xhx9pzhj 30 28 disease disease NN cord-005646-xhx9pzhj 30 29 ( ( -LRB- cord-005646-xhx9pzhj 30 30 n=342 n=342 CD cord-005646-xhx9pzhj 30 31 , , , cord-005646-xhx9pzhj 30 32 mortality mortality NN cord-005646-xhx9pzhj 30 33 38.7 38.7 CD cord-005646-xhx9pzhj 30 34 % % NN cord-005646-xhx9pzhj 30 35 ) ) -RRB- cord-005646-xhx9pzhj 30 36 , , , cord-005646-xhx9pzhj 30 37 and and CC cord-005646-xhx9pzhj 30 38 systemic systemic JJ cord-005646-xhx9pzhj 30 39 inflammation inflammation NN cord-005646-xhx9pzhj 30 40 or or CC cord-005646-xhx9pzhj 30 41 multisystem multisystem JJ cord-005646-xhx9pzhj 30 42 ( ( -LRB- cord-005646-xhx9pzhj 30 43 SIMS SIMS NNP cord-005646-xhx9pzhj 30 44 ) ) -RRB- cord-005646-xhx9pzhj 30 45 disease disease NN cord-005646-xhx9pzhj 30 46 ( ( -LRB- cord-005646-xhx9pzhj 30 47 n=137 n=137 CD cord-005646-xhx9pzhj 30 48 , , , cord-005646-xhx9pzhj 30 49 mortality mortality NN cord-005646-xhx9pzhj 30 50 47.5 47.5 CD cord-005646-xhx9pzhj 30 51 % % NN cord-005646-xhx9pzhj 30 52 . . . cord-005646-xhx9pzhj 31 1 The the DT cord-005646-xhx9pzhj 31 2 LOS LOS NNP cord-005646-xhx9pzhj 31 3 in in IN cord-005646-xhx9pzhj 31 4 survivors survivor NNS cord-005646-xhx9pzhj 31 5 was be VBD cord-005646-xhx9pzhj 31 6 : : : cord-005646-xhx9pzhj 31 7 respiratory respiratory JJ cord-005646-xhx9pzhj 32 1 -median -median JJ cord-005646-xhx9pzhj 32 2 ( ( -LRB- cord-005646-xhx9pzhj 32 3 interquartile interquartile JJ cord-005646-xhx9pzhj 32 4 range range NN cord-005646-xhx9pzhj 32 5 ) ) -RRB- cord-005646-xhx9pzhj 32 6 8(4 8(4 CD cord-005646-xhx9pzhj 32 7 - - HYPH cord-005646-xhx9pzhj 32 8 16 16 CD cord-005646-xhx9pzhj 32 9 ) ) -RRB- cord-005646-xhx9pzhj 32 10 days day NNS cord-005646-xhx9pzhj 32 11 , , , cord-005646-xhx9pzhj 32 12 CNS CNS NNP cord-005646-xhx9pzhj 32 13 4(3 4(3 NNP cord-005646-xhx9pzhj 32 14 - - HYPH cord-005646-xhx9pzhj 32 15 8 8 CD cord-005646-xhx9pzhj 32 16 ) ) -RRB- cord-005646-xhx9pzhj 32 17 days day NNS cord-005646-xhx9pzhj 32 18 , , , cord-005646-xhx9pzhj 32 19 £ £ NN cord-005646-xhx9pzhj 32 20 p,4 p,4 NN cord-005646-xhx9pzhj 32 21 £ £ $ cord-005646-xhx9pzhj 32 22 5(7-g 5(7-g CD cord-005646-xhx9pzhj 32 23 ) ) -RRB- cord-005646-xhx9pzhj 32 24 days day NNS cord-005646-xhx9pzhj 32 25 . . . cord-005646-xhx9pzhj 33 1 5 5 LS cord-005646-xhx9pzhj 33 2 : : : cord-005646-xhx9pzhj 34 1 i'~'-+cen i'~'-+cen NNP cord-005646-xhx9pzhj 35 1 diag~,~is diag~,~is VB cord-005646-xhx9pzhj 35 2 - - JJ cord-005646-xhx9pzhj 35 3 rc!ated rc!ate VBN cord-005646-xhx9pzhj 35 4 - - HYPH cord-005646-xhx9pzhj 35 5 grnnp~ grnnp~ NNP cord-005646-xhx9pzhj 35 6 ( ( -LRB- cord-005646-xhx9pzhj 35 7 DRGs DRGs NNP cord-005646-xhx9pzhj 35 8 ) ) -RRB- cord-005646-xhx9pzhj 35 9 were be VBD cord-005646-xhx9pzhj 35 10 identified identify VBN cord-005646-xhx9pzhj 35 11 ( ( -LRB- cord-005646-xhx9pzhj 35 12 8 8 CD cord-005646-xhx9pzhj 35 13 respiratory respiratory NN cord-005646-xhx9pzhj 35 14 , , , cord-005646-xhx9pzhj 35 15 5 5 CD cord-005646-xhx9pzhj 35 16 CNS CNS NNP cord-005646-xhx9pzhj 35 17 , , , cord-005646-xhx9pzhj 35 18 3 3 CD cord-005646-xhx9pzhj 35 19 SIMS sims NN cord-005646-xhx9pzhj 35 20 disease disease NN cord-005646-xhx9pzhj 35 21 ) ) -RRB- cord-005646-xhx9pzhj 35 22 and and CC cord-005646-xhx9pzhj 35 23 each each DT cord-005646-xhx9pzhj 35 24 have have VBP cord-005646-xhx9pzhj 35 25 been be VBN cord-005646-xhx9pzhj 35 26 characterised characterise VBN cord-005646-xhx9pzhj 35 27 by by IN cord-005646-xhx9pzhj 35 28 mortality mortality NN cord-005646-xhx9pzhj 35 29 and and CC cord-005646-xhx9pzhj 35 30 LOS LOS NNP cord-005646-xhx9pzhj 35 31 . . . cord-005646-xhx9pzhj 36 1 Study Study NNP cord-005646-xhx9pzhj 36 2 II II NNP cord-005646-xhx9pzhj 36 3 ( ( -LRB- cord-005646-xhx9pzhj 36 4 n=300 n=300 NNP cord-005646-xhx9pzhj 36 5 ) ) -RRB- cord-005646-xhx9pzhj 36 6 : : : cord-005646-xhx9pzhj 37 1 A a DT cord-005646-xhx9pzhj 37 2 prospective prospective JJ cord-005646-xhx9pzhj 37 3 study study NN cord-005646-xhx9pzhj 37 4 of of IN cord-005646-xhx9pzhj 37 5 patients patient NNS cord-005646-xhx9pzhj 37 6 supported support VBN cord-005646-xhx9pzhj 37 7 by by IN cord-005646-xhx9pzhj 37 8 the the DT cord-005646-xhx9pzhj 37 9 hypothesis hypothesis NN cord-005646-xhx9pzhj 37 10 that that IN cord-005646-xhx9pzhj 37 11 LOS LOS NNP cord-005646-xhx9pzhj 37 12 for for IN cord-005646-xhx9pzhj 37 13 the the DT cord-005646-xhx9pzhj 37 14 above above JJ cord-005646-xhx9pzhj 37 15 DRGs drg NNS cord-005646-xhx9pzhj 37 16 was be VBD cord-005646-xhx9pzhj 37 17 predictable predictable JJ cord-005646-xhx9pzhj 37 18 ( ( -LRB- cord-005646-xhx9pzhj 37 19 compared compare VBN cord-005646-xhx9pzhj 37 20 with with IN cord-005646-xhx9pzhj 37 21 Study study NN cord-005646-xhx9pzhj 37 22 I I NNP cord-005646-xhx9pzhj 37 23 data datum NNS cord-005646-xhx9pzhj 37 24 ) ) -RRB- cord-005646-xhx9pzhj 37 25 . . . cord-005646-xhx9pzhj 38 1 In in IN cord-005646-xhx9pzhj 38 2 certain certain JJ cord-005646-xhx9pzhj 38 3 instances instance NNS cord-005646-xhx9pzhj 38 4 attributable attributable JJ cord-005646-xhx9pzhj 38 5 causes cause NNS cord-005646-xhx9pzhj 38 6 for for IN cord-005646-xhx9pzhj 38 7 variances variance NNS cord-005646-xhx9pzhj 38 8 in in IN cord-005646-xhx9pzhj 38 9 LOS LOS NNP cord-005646-xhx9pzhj 38 10 were be VBD cord-005646-xhx9pzhj 38 11 identified identify VBN cord-005646-xhx9pzhj 38 12 : : : cord-005646-xhx9pzhj 38 13 e.g. e.g. IN cord-005646-xhx9pzhj 38 14 disease disease NN cord-005646-xhx9pzhj 38 15 severity severity NN cord-005646-xhx9pzhj 38 16 , , , cord-005646-xhx9pzhj 38 17 timing time VBG cord-005646-xhx9pzhj 38 18 ofdrug ofdrug NN cord-005646-xhx9pzhj 38 19 therapy therapy NN cord-005646-xhx9pzhj 38 20 , , , cord-005646-xhx9pzhj 38 21 and and CC cord-005646-xhx9pzhj 38 22 associated associated JJ cord-005646-xhx9pzhj 38 23 disease disease NN cord-005646-xhx9pzhj 38 24 . . . cord-005646-xhx9pzhj 39 1 With with IN cord-005646-xhx9pzhj 39 2 daily daily JJ cord-005646-xhx9pzhj 39 3 paediatric paediatric JJ cord-005646-xhx9pzhj 39 4 risk risk NN cord-005646-xhx9pzhj 39 5 of of IN cord-005646-xhx9pzhj 39 6 morality morality NN cord-005646-xhx9pzhj 39 7 scoring scoring NN cord-005646-xhx9pzhj 39 8 within within IN cord-005646-xhx9pzhj 39 9 each each DT cord-005646-xhx9pzhj 39 10 DRG DRG NNP cord-005646-xhx9pzhj 39 11 , , , cord-005646-xhx9pzhj 39 12 four four CD cord-005646-xhx9pzhj 39 13 profiles profile NNS cord-005646-xhx9pzhj 39 14 of of IN cord-005646-xhx9pzhj 39 15 instability instability NN cord-005646-xhx9pzhj 39 16 were be VBD cord-005646-xhx9pzhj 39 17 identified identify VBN cord-005646-xhx9pzhj 39 18 . . . cord-005646-xhx9pzhj 40 1 Discussion discussion NN cord-005646-xhx9pzhj 40 2 : : : cord-005646-xhx9pzhj 41 1 The the DT cord-005646-xhx9pzhj 41 2 time time NN cord-005646-xhx9pzhj 41 3 course course NN cord-005646-xhx9pzhj 41 4 of of IN cord-005646-xhx9pzhj 41 5 acute acute JJ cord-005646-xhx9pzhj 41 6 severe severe JJ cord-005646-xhx9pzhj 41 7 medical medical JJ cord-005646-xhx9pzhj 41 8 illness illness NN cord-005646-xhx9pzhj 41 9 with with IN cord-005646-xhx9pzhj 41 10 respiratory respiratory JJ cord-005646-xhx9pzhj 41 11 failure failure NN cord-005646-xhx9pzhj 41 12 is be VBZ cord-005646-xhx9pzhj 41 13 predictable predictable JJ cord-005646-xhx9pzhj 41 14 and and CC cord-005646-xhx9pzhj 41 15 variance variance NN cord-005646-xhx9pzhj 41 16 may may MD cord-005646-xhx9pzhj 41 17 be be VB cord-005646-xhx9pzhj 41 18 attributable attributable JJ cord-005646-xhx9pzhj 41 19 to to IN cord-005646-xhx9pzhj 41 20 specific specific JJ cord-005646-xhx9pzhj 41 21 care care NN cord-005646-xhx9pzhj 41 22 or or CC cord-005646-xhx9pzhj 41 23 diagnostic diagnostic JJ cord-005646-xhx9pzhj 41 24 factors factor NNS cord-005646-xhx9pzhj 41 25 . . . cord-005646-xhx9pzhj 42 1 We -PRON- PRP cord-005646-xhx9pzhj 42 2 are be VBP cord-005646-xhx9pzhj 42 3 now now RB cord-005646-xhx9pzhj 42 4 developing develop VBG cord-005646-xhx9pzhj 42 5 a a DT cord-005646-xhx9pzhj 42 6 means means NN cord-005646-xhx9pzhj 42 7 of of IN cord-005646-xhx9pzhj 42 8 linking link VBG cord-005646-xhx9pzhj 42 9 DRG drg NN cord-005646-xhx9pzhj 42 10 - - HYPH cord-005646-xhx9pzhj 42 11 specific specific JJ cord-005646-xhx9pzhj 42 12 clinical clinical JJ cord-005646-xhx9pzhj 42 13 care care NN cord-005646-xhx9pzhj 42 14 pathways pathway NNS cord-005646-xhx9pzhj 42 15 with with IN cord-005646-xhx9pzhj 42 16 an an DT cord-005646-xhx9pzhj 42 17 integrated integrated JJ cord-005646-xhx9pzhj 42 18 computerised computerised JJ cord-005646-xhx9pzhj 42 19 decision decision NN cord-005646-xhx9pzhj 42 20 support support NN cord-005646-xhx9pzhj 42 21 and and CC cord-005646-xhx9pzhj 42 22 education education NN cord-005646-xhx9pzhj 42 23 facility facility NN cord-005646-xhx9pzhj 42 24 at at IN cord-005646-xhx9pzhj 42 25 the the DT cord-005646-xhx9pzhj 42 26 bedside bedside NN cord-005646-xhx9pzhj 42 27 . . . cord-005646-xhx9pzhj 43 1 The the DT cord-005646-xhx9pzhj 43 2 objective objective NN cord-005646-xhx9pzhj 43 3 of of IN cord-005646-xhx9pzhj 43 4 this this DT cord-005646-xhx9pzhj 43 5 open open JJ cord-005646-xhx9pzhj 43 6 , , , cord-005646-xhx9pzhj 43 7 prospective prospective JJ cord-005646-xhx9pzhj 43 8 study study NN cord-005646-xhx9pzhj 43 9 was be VBD cord-005646-xhx9pzhj 43 10 to to TO cord-005646-xhx9pzhj 43 11 assess assess VB cord-005646-xhx9pzhj 43 12 the the DT cord-005646-xhx9pzhj 43 13 relation relation NN cord-005646-xhx9pzhj 43 14 between between IN cord-005646-xhx9pzhj 43 15 basic basic JJ cord-005646-xhx9pzhj 43 16 patient patient JJ cord-005646-xhx9pzhj 43 17 characteristics characteristic NNS cord-005646-xhx9pzhj 43 18 as as RB cord-005646-xhx9pzhj 43 19 well well RB cord-005646-xhx9pzhj 43 20 as as IN cord-005646-xhx9pzhj 43 21 effectiveness effectiveness NN cord-005646-xhx9pzhj 43 22 of of IN cord-005646-xhx9pzhj 43 23 treatment treatment NN cord-005646-xhx9pzhj 43 24 on on IN cord-005646-xhx9pzhj 43 25 the the DT cord-005646-xhx9pzhj 43 26 one one CD cord-005646-xhx9pzhj 43 27 hand hand NN cord-005646-xhx9pzhj 43 28 and and CC cord-005646-xhx9pzhj 43 29 resource resource NN cord-005646-xhx9pzhj 43 30 utilization utilization NN cord-005646-xhx9pzhj 43 31 in in IN cord-005646-xhx9pzhj 43 32 pediatric pediatric JJ cord-005646-xhx9pzhj 43 33 intensive intensive JJ cord-005646-xhx9pzhj 43 34 care care NN cord-005646-xhx9pzhj 43 35 on on IN cord-005646-xhx9pzhj 43 36 the the DT cord-005646-xhx9pzhj 43 37 other other JJ cord-005646-xhx9pzhj 43 38 . . . cord-005646-xhx9pzhj 44 1 As as IN cord-005646-xhx9pzhj 44 2 universal universal JJ cord-005646-xhx9pzhj 44 3 , , , cord-005646-xhx9pzhj 44 4 non non JJ cord-005646-xhx9pzhj 44 5 - - JJ cord-005646-xhx9pzhj 44 6 monetary monetary JJ cord-005646-xhx9pzhj 44 7 indicators indicator NNS cord-005646-xhx9pzhj 44 8 of of IN cord-005646-xhx9pzhj 44 9 resource resource NN cord-005646-xhx9pzhj 44 10 utilization utilization NN cord-005646-xhx9pzhj 44 11 we -PRON- PRP cord-005646-xhx9pzhj 44 12 used use VBD cord-005646-xhx9pzhj 44 13 the the DT cord-005646-xhx9pzhj 44 14 Therapeutic Therapeutic NNP cord-005646-xhx9pzhj 44 15 Intervention Intervention NNP cord-005646-xhx9pzhj 44 16 Score Score NNP cord-005646-xhx9pzhj 44 17 System System NNP cord-005646-xhx9pzhj 44 18 ( ( -LRB- cord-005646-xhx9pzhj 44 19 TISS TISS NNP cord-005646-xhx9pzhj 44 20 ) ) -RRB- cord-005646-xhx9pzhj 44 21 and and CC cord-005646-xhx9pzhj 44 22 length length NN cord-005646-xhx9pzhj 44 23 - - HYPH cord-005646-xhx9pzhj 44 24 ofstay ofstay FW cord-005646-xhx9pzhj 44 25 ( ( -LRB- cord-005646-xhx9pzhj 44 26 LOS LOS NNP cord-005646-xhx9pzhj 44 27 ) ) -RRB- cord-005646-xhx9pzhj 44 28 , , , cord-005646-xhx9pzhj 44 29 from from IN cord-005646-xhx9pzhj 44 30 which which WDT cord-005646-xhx9pzhj 44 31 indicators indicator NNS cord-005646-xhx9pzhj 44 32 for for IN cord-005646-xhx9pzhj 44 33 total total JJ cord-005646-xhx9pzhj 44 34 resource resource NN cord-005646-xhx9pzhj 44 35 utilization utilization NN cord-005646-xhx9pzhj 44 36 per per IN cord-005646-xhx9pzhj 44 37 admission admission NN cord-005646-xhx9pzhj 44 38 ( ( -LRB- cord-005646-xhx9pzhj 44 39 TISSTOT TISSTOT NNP cord-005646-xhx9pzhj 44 40 ) ) -RRB- cord-005646-xhx9pzhj 44 41 and and CC cord-005646-xhx9pzhj 44 42 average average JJ cord-005646-xhx9pzhj 44 43 daily daily JJ cord-005646-xhx9pzhj 44 44 resource resource NN cord-005646-xhx9pzhj 44 45 utilization utilization NN cord-005646-xhx9pzhj 45 1 ( ( -LRB- cord-005646-xhx9pzhj 45 2 TISS TISS NNP cord-005646-xhx9pzhj 45 3 - - HYPH cord-005646-xhx9pzhj 45 4 MEAN MEAN NNP cord-005646-xhx9pzhj 46 1 = = NFP cord-005646-xhx9pzhj 46 2 TISSTOT TISSTOT NNP cord-005646-xhx9pzhj 46 3 / / SYM cord-005646-xhx9pzhj 46 4 LOS LOS NNP cord-005646-xhx9pzhj 46 5 ) ) -RRB- cord-005646-xhx9pzhj 46 6 were be VBD cord-005646-xhx9pzhj 46 7 obtained obtain VBN cord-005646-xhx9pzhj 46 8 . . . cord-005646-xhx9pzhj 47 1 Overall overall JJ cord-005646-xhx9pzhj 47 2 593 593 CD cord-005646-xhx9pzhj 47 3 admissions admission NNS cord-005646-xhx9pzhj 47 4 , , , cord-005646-xhx9pzhj 47 5 totalling total VBG cord-005646-xhx9pzhj 47 6 3130 3130 CD cord-005646-xhx9pzhj 47 7 days day NNS cord-005646-xhx9pzhj 47 8 , , , cord-005646-xhx9pzhj 47 9 were be VBD cord-005646-xhx9pzhj 47 10 included include VBN cord-005646-xhx9pzhj 47 11 . . . cord-005646-xhx9pzhj 48 1 Mortality mortality NN cord-005646-xhx9pzhj 48 2 was be VBD cord-005646-xhx9pzhj 48 3 8.4 8.4 CD cord-005646-xhx9pzhj 48 4 % % NN cord-005646-xhx9pzhj 48 5 ; ; , cord-005646-xhx9pzhj 48 6 non non NNS cord-005646-xhx9pzhj 48 7 - - NNS cord-005646-xhx9pzhj 48 8 survivors survivor NNS cord-005646-xhx9pzhj 48 9 accounted account VBD cord-005646-xhx9pzhj 48 10 for for IN cord-005646-xhx9pzhj 48 11 14.1 14.1 CD cord-005646-xhx9pzhj 48 12 % % NN cord-005646-xhx9pzhj 48 13 of of IN cord-005646-xhx9pzhj 48 14 overall overall JJ cord-005646-xhx9pzhj 48 15 resource resource NN cord-005646-xhx9pzhj 48 16 utilization utilization NN cord-005646-xhx9pzhj 48 17 . . . cord-005646-xhx9pzhj 49 1 In in IN cord-005646-xhx9pzhj 49 2 non non NNS cord-005646-xhx9pzhj 49 3 - - NNS cord-005646-xhx9pzhj 49 4 survivors survivor NNS cord-005646-xhx9pzhj 49 5 , , , cord-005646-xhx9pzhj 49 6 both both DT cord-005646-xhx9pzhj 49 7 total total JJ cord-005646-xhx9pzhj 49 8 resource resource NN cord-005646-xhx9pzhj 49 9 utilization utilization NN cord-005646-xhx9pzhj 49 10 per per IN cord-005646-xhx9pzhj 49 11 admission admission NN cord-005646-xhx9pzhj 49 12 and and CC cord-005646-xhx9pzhj 49 13 average average JJ cord-005646-xhx9pzhj 49 14 daily daily JJ cord-005646-xhx9pzhj 49 15 resource resource NN cord-005646-xhx9pzhj 49 16 utilization utilization NN cord-005646-xhx9pzhj 49 17 were be VBD cord-005646-xhx9pzhj 49 18 higher high JJR cord-005646-xhx9pzhj 49 19 , , , cord-005646-xhx9pzhj 49 20 whereas whereas IN cord-005646-xhx9pzhj 49 21 LOS LOS NNP cord-005646-xhx9pzhj 49 22 was be VBD cord-005646-xhx9pzhj 49 23 not not RB cord-005646-xhx9pzhj 49 24 different different JJ cord-005646-xhx9pzhj 49 25 from from IN cord-005646-xhx9pzhj 49 26 survivors survivor NNS cord-005646-xhx9pzhj 49 27 ' ' '' cord-005646-xhx9pzhj 49 28 . . . cord-005646-xhx9pzhj 50 1 Severity severity NN cord-005646-xhx9pzhj 50 2 of of IN cord-005646-xhx9pzhj 50 3 illness illness NN cord-005646-xhx9pzhj 50 4 , , , cord-005646-xhx9pzhj 50 5 surgical surgical JJ cord-005646-xhx9pzhj 50 6 status status NN cord-005646-xhx9pzhj 50 7 , , , cord-005646-xhx9pzhj 50 8 the the DT cord-005646-xhx9pzhj 50 9 presence presence NN cord-005646-xhx9pzhj 50 10 of of IN cord-005646-xhx9pzhj 50 11 substantial substantial JJ cord-005646-xhx9pzhj 50 12 chronic chronic JJ cord-005646-xhx9pzhj 50 13 comorbidity comorbidity NN cord-005646-xhx9pzhj 50 14 , , , cord-005646-xhx9pzhj 50 15 emergency emergency NN cord-005646-xhx9pzhj 50 16 admission admission NN cord-005646-xhx9pzhj 50 17 and and CC cord-005646-xhx9pzhj 50 18 transfer transfer NN cord-005646-xhx9pzhj 50 19 from from IN cord-005646-xhx9pzhj 50 20 another another DT cord-005646-xhx9pzhj 50 21 hospital hospital NN cord-005646-xhx9pzhj 50 22 constituted constitute VBD cord-005646-xhx9pzhj 50 23 the the DT cord-005646-xhx9pzhj 50 24 major major JJ cord-005646-xhx9pzhj 50 25 predictive predictive JJ cord-005646-xhx9pzhj 50 26 determinants determinant NNS cord-005646-xhx9pzhj 50 27 of of IN cord-005646-xhx9pzhj 50 28 TISSTOT TISSTOT NNP cord-005646-xhx9pzhj 50 29 ( ( -LRB- cord-005646-xhx9pzhj 50 30 r:=0.19 r:=0.19 NNP cord-005646-xhx9pzhj 50 31 ) ) -RRB- cord-005646-xhx9pzhj 50 32 and and CC cord-005646-xhx9pzhj 50 33 TISSMEAN TISSMEAN NNP cord-005646-xhx9pzhj 50 34 ( ( -LRB- cord-005646-xhx9pzhj 50 35 ra=0.45 ra=0.45 NNP cord-005646-xhx9pzhj 50 36 ) ) -RRB- cord-005646-xhx9pzhj 50 37 in in IN cord-005646-xhx9pzhj 50 38 multiple multiple JJ cord-005646-xhx9pzhj 50 39 regression regression NN cord-005646-xhx9pzhj 50 40 analysis analysis NN cord-005646-xhx9pzhj 50 41 ( ( -LRB- cord-005646-xhx9pzhj 50 42 p<0.0001 p<0.0001 NNP cord-005646-xhx9pzhj 50 43 ) ) -RRB- cord-005646-xhx9pzhj 50 44 . . . cord-005646-xhx9pzhj 51 1 Hence hence RB cord-005646-xhx9pzhj 51 2 these these DT cord-005646-xhx9pzhj 51 3 indicators indicator NNS cord-005646-xhx9pzhj 51 4 are be VBP cord-005646-xhx9pzhj 51 5 appropriate appropriate JJ cord-005646-xhx9pzhj 51 6 non non JJ cord-005646-xhx9pzhj 51 7 - - JJ cord-005646-xhx9pzhj 51 8 monetary monetary JJ cord-005646-xhx9pzhj 51 9 measures measure NNS cord-005646-xhx9pzhj 51 10 of of IN cord-005646-xhx9pzhj 51 11 resource resource NN cord-005646-xhx9pzhj 51 12 utilization utilization NN cord-005646-xhx9pzhj 51 13 , , , cord-005646-xhx9pzhj 51 14 a a DT cord-005646-xhx9pzhj 51 15 considerable considerable JJ cord-005646-xhx9pzhj 51 16 proportion proportion NN cord-005646-xhx9pzhj 51 17 of of IN cord-005646-xhx9pzhj 51 18 which which WDT cord-005646-xhx9pzhj 51 19 are be VBP cord-005646-xhx9pzhj 51 20 determined determine VBN cord-005646-xhx9pzhj 51 21 by by IN cord-005646-xhx9pzhj 51 22 a a DT cord-005646-xhx9pzhj 51 23 concise concise JJ cord-005646-xhx9pzhj 51 24 set set NN cord-005646-xhx9pzhj 51 25 of of IN cord-005646-xhx9pzhj 51 26 basic basic JJ cord-005646-xhx9pzhj 51 27 clinical clinical JJ cord-005646-xhx9pzhj 51 28 characteristics characteristic NNS cord-005646-xhx9pzhj 51 29 . . . cord-005646-xhx9pzhj 52 1 Subsequently subsequently RB cord-005646-xhx9pzhj 52 2 we -PRON- PRP cord-005646-xhx9pzhj 52 3 analysed analyse VBD cord-005646-xhx9pzhj 52 4 the the DT cord-005646-xhx9pzhj 52 5 relation relation NN cord-005646-xhx9pzhj 52 6 between between IN cord-005646-xhx9pzhj 52 7 effectiveness effectiveness NN cord-005646-xhx9pzhj 52 8 of of IN cord-005646-xhx9pzhj 52 9 care care NN cord-005646-xhx9pzhj 52 10 and and CC cord-005646-xhx9pzhj 52 11 resource resource NN cord-005646-xhx9pzhj 52 12 utilization utilization NN cord-005646-xhx9pzhj 52 13 by by IN cord-005646-xhx9pzhj 52 14 assessing assess VBG cord-005646-xhx9pzhj 52 15 severity severity NN cord-005646-xhx9pzhj 52 16 of of IN cord-005646-xhx9pzhj 52 17 illness illness NN cord-005646-xhx9pzhj 52 18 corrected correct VBD cord-005646-xhx9pzhj 52 19 mortality mortality NN cord-005646-xhx9pzhj 52 20 in in IN cord-005646-xhx9pzhj 52 21 low low JJ cord-005646-xhx9pzhj 52 22 , , , cord-005646-xhx9pzhj 52 23 medium medium JJ cord-005646-xhx9pzhj 52 24 and and CC cord-005646-xhx9pzhj 52 25 high high JJ cord-005646-xhx9pzhj 52 26 resource resource NN cord-005646-xhx9pzhj 52 27 users user NNS cord-005646-xhx9pzhj 52 28 , , , cord-005646-xhx9pzhj 52 29 respectively respectively RB cord-005646-xhx9pzhj 52 30 . . . cord-005646-xhx9pzhj 53 1 These these DT cord-005646-xhx9pzhj 53 2 3 3 CD cord-005646-xhx9pzhj 53 3 categories category NNS cord-005646-xhx9pzhj 53 4 were be VBD cord-005646-xhx9pzhj 53 5 delineated delineate VBN cord-005646-xhx9pzhj 53 6 by by IN cord-005646-xhx9pzhj 53 7 percer percer NN cord-005646-xhx9pzhj 53 8 / / SYM cord-005646-xhx9pzhj 53 9 tiles tile NNS cord-005646-xhx9pzhj 53 10 of of IN cord-005646-xhx9pzhj 53 11 resource resource NN cord-005646-xhx9pzhj 53 12 utilization utilization NN cord-005646-xhx9pzhj 53 13 ( ( -LRB- cord-005646-xhx9pzhj 53 14 < < XX cord-005646-xhx9pzhj 53 15 P20 P20 NNP cord-005646-xhx9pzhj 53 16 , , , cord-005646-xhx9pzhj 53 17 P20-PS0 P20-PS0 NNP cord-005646-xhx9pzhj 53 18 , , , cord-005646-xhx9pzhj 53 19 > > : cord-005646-xhx9pzhj 53 20 Ps0 ps0 CD cord-005646-xhx9pzhj 53 21 ) ) -RRB- cord-005646-xhx9pzhj 53 22 . . . cord-005646-xhx9pzhj 54 1 Despite despite IN cord-005646-xhx9pzhj 54 2 on on IN cord-005646-xhx9pzhj 54 3 average average JJ cord-005646-xhx9pzhj 54 4 long long JJ cord-005646-xhx9pzhj 54 5 LOS LOS NNP cord-005646-xhx9pzhj 54 6 and and CC cord-005646-xhx9pzhj 54 7 high high JJ cord-005646-xhx9pzhj 54 8 resource resource NN cord-005646-xhx9pzhj 54 9 utilization utilization NN cord-005646-xhx9pzhj 54 10 in in IN cord-005646-xhx9pzhj 54 11 the the DT cord-005646-xhx9pzhj 54 12 high high JJ cord-005646-xhx9pzhj 54 13 risk risk NN cord-005646-xhx9pzhj 54 14 group group NN cord-005646-xhx9pzhj 54 15 , , , cord-005646-xhx9pzhj 54 16 a a DT cord-005646-xhx9pzhj 54 17 relatively relatively RB cord-005646-xhx9pzhj 54 18 low low JJ cord-005646-xhx9pzhj 54 19 standardized standardized JJ cord-005646-xhx9pzhj 54 20 mortality mortality NN cord-005646-xhx9pzhj 54 21 was be VBD cord-005646-xhx9pzhj 54 22 found find VBN cord-005646-xhx9pzhj 54 23 , , , cord-005646-xhx9pzhj 54 24 probably probably RB cord-005646-xhx9pzhj 54 25 warranting warrant VBG cord-005646-xhx9pzhj 54 26 prolonged prolonged JJ cord-005646-xhx9pzhj 54 27 intensive intensive JJ cord-005646-xhx9pzhj 54 28 treatment treatment NN cord-005646-xhx9pzhj 54 29 in in IN cord-005646-xhx9pzhj 54 30 this this DT cord-005646-xhx9pzhj 54 31 patient patient NN cord-005646-xhx9pzhj 54 32 category category NN cord-005646-xhx9pzhj 54 33 . . . cord-005646-xhx9pzhj 55 1 SUMMARY summary NN cord-005646-xhx9pzhj 55 2 : : : cord-005646-xhx9pzhj 56 1 Objective objective JJ cord-005646-xhx9pzhj 56 2 : : : cord-005646-xhx9pzhj 56 3 The the DT cord-005646-xhx9pzhj 56 4 primary primary JJ cord-005646-xhx9pzhj 56 5 purposes purpose NNS cord-005646-xhx9pzhj 56 6 of of IN cord-005646-xhx9pzhj 56 7 intensive intensive JJ cord-005646-xhx9pzhj 56 8 care care NN cord-005646-xhx9pzhj 56 9 are be VBP cord-005646-xhx9pzhj 56 10 to to TO cord-005646-xhx9pzhj 56 11 provide provide VB cord-005646-xhx9pzhj 56 12 treatments treatment NNS cord-005646-xhx9pzhj 56 13 to to IN cord-005646-xhx9pzhj 56 14 patients patient NNS cord-005646-xhx9pzhj 56 15 with with IN cord-005646-xhx9pzhj 56 16 life life NN cord-005646-xhx9pzhj 56 17 - - HYPH cord-005646-xhx9pzhj 56 18 threatening threaten VBG cord-005646-xhx9pzhj 56 19 physiological physiological JJ cord-005646-xhx9pzhj 56 20 dysfunction dysfunction NN cord-005646-xhx9pzhj 56 21 or or CC cord-005646-xhx9pzhj 56 22 to to TO cord-005646-xhx9pzhj 56 23 monitor monitor VB cord-005646-xhx9pzhj 56 24 and and CC cord-005646-xhx9pzhj 56 25 observe observe VB cord-005646-xhx9pzhj 56 26 patients patient NNS cord-005646-xhx9pzhj 56 27 perceived perceive VBN cord-005646-xhx9pzhj 56 28 to to TO cord-005646-xhx9pzhj 56 29 be be VB cord-005646-xhx9pzhj 56 30 at at IN cord-005646-xhx9pzhj 56 31 significant significant JJ cord-005646-xhx9pzhj 56 32 risk risk NN cord-005646-xhx9pzhj 56 33 of of IN cord-005646-xhx9pzhj 56 34 dying die VBG cord-005646-xhx9pzhj 56 35 . . . cord-005646-xhx9pzhj 57 1 This this DT cord-005646-xhx9pzhj 57 2 collaborative collaborative JJ cord-005646-xhx9pzhj 57 3 study study NN cord-005646-xhx9pzhj 57 4 was be VBD cord-005646-xhx9pzhj 57 5 performed perform VBN cord-005646-xhx9pzhj 57 6 to to TO cord-005646-xhx9pzhj 57 7 describe describe VB cord-005646-xhx9pzhj 57 8 our -PRON- PRP$ cord-005646-xhx9pzhj 57 9 patients patient NNS cord-005646-xhx9pzhj 57 10 and and CC cord-005646-xhx9pzhj 57 11 their -PRON- PRP$ cord-005646-xhx9pzhj 57 12 outcome outcome NN cord-005646-xhx9pzhj 57 13 . . . cord-005646-xhx9pzhj 58 1 In in IN cord-005646-xhx9pzhj 58 2 order order NN cord-005646-xhx9pzhj 58 3 to to TO cord-005646-xhx9pzhj 58 4 improve improve VB cord-005646-xhx9pzhj 58 5 our -PRON- PRP$ cord-005646-xhx9pzhj 58 6 results result NNS cord-005646-xhx9pzhj 58 7 we -PRON- PRP cord-005646-xhx9pzhj 58 8 tried try VBD cord-005646-xhx9pzhj 58 9 to to IN cord-005646-xhx9pzhj 58 10 identit~ identit~ NNP cord-005646-xhx9pzhj 58 11 high high JJ cord-005646-xhx9pzhj 58 12 risk risk NN cord-005646-xhx9pzhj 58 13 groups group NNS cord-005646-xhx9pzhj 58 14 , , , cord-005646-xhx9pzhj 58 15 Patients Patients NNPS cord-005646-xhx9pzhj 58 16 and and CC cord-005646-xhx9pzhj 58 17 Methods Methods NNPS cord-005646-xhx9pzhj 58 18 : : : cord-005646-xhx9pzhj 58 19 13 13 CD cord-005646-xhx9pzhj 58 20 PICUs picu NNS cord-005646-xhx9pzhj 58 21 entered enter VBD cord-005646-xhx9pzhj 58 22 the the DT cord-005646-xhx9pzhj 58 23 study study NN cord-005646-xhx9pzhj 58 24 , , , cord-005646-xhx9pzhj 58 25 The the DT cord-005646-xhx9pzhj 58 26 data datum NNS cord-005646-xhx9pzhj 58 27 included include VBD cord-005646-xhx9pzhj 58 28 all all PDT cord-005646-xhx9pzhj 58 29 the the DT cord-005646-xhx9pzhj 58 30 admissions admission NNS cord-005646-xhx9pzhj 58 31 with with IN cord-005646-xhx9pzhj 58 32 > > XX cord-005646-xhx9pzhj 58 33 12 12 CD cord-005646-xhx9pzhj 58 34 hs hs NNP cord-005646-xhx9pzhj 58 35 . . . cord-005646-xhx9pzhj 59 1 during during IN cord-005646-xhx9pzhj 59 2 a a DT cord-005646-xhx9pzhj 59 3 60 60 CD cord-005646-xhx9pzhj 59 4 days day NNS cord-005646-xhx9pzhj 59 5 period period NN cord-005646-xhx9pzhj 59 6 between between IN cord-005646-xhx9pzhj 59 7 the the DT cord-005646-xhx9pzhj 59 8 l l NNP cord-005646-xhx9pzhj 59 9 ° ° NNP cord-005646-xhx9pzhj 59 10 June June NNP cord-005646-xhx9pzhj 59 11 and and CC cord-005646-xhx9pzhj 59 12 the the DT cord-005646-xhx9pzhj 59 13 30th 30th JJ cord-005646-xhx9pzhj 59 14 September September NNP cord-005646-xhx9pzhj 59 15 1993 1993 CD cord-005646-xhx9pzhj 59 16 . . . cord-005646-xhx9pzhj 60 1 The the DT cord-005646-xhx9pzhj 60 2 records record NNS cord-005646-xhx9pzhj 60 3 included include VBD cord-005646-xhx9pzhj 60 4 : : : cord-005646-xhx9pzhj 60 5 age age NN cord-005646-xhx9pzhj 60 6 , , , cord-005646-xhx9pzhj 60 7 sex sex NN cord-005646-xhx9pzhj 60 8 , , , cord-005646-xhx9pzhj 60 9 weight weight NN cord-005646-xhx9pzhj 60 10 , , , cord-005646-xhx9pzhj 60 11 mechanical mechanical JJ cord-005646-xhx9pzhj 60 12 ventilation ventilation NN cord-005646-xhx9pzhj 60 13 ( ( -LRB- cord-005646-xhx9pzhj 60 14 MV MV NNP cord-005646-xhx9pzhj 60 15 ) ) -RRB- cord-005646-xhx9pzhj 60 16 , , , cord-005646-xhx9pzhj 60 17 post post JJ cord-005646-xhx9pzhj 60 18 - - JJ cord-005646-xhx9pzhj 60 19 operative operative JJ cord-005646-xhx9pzhj 60 20 condition condition NN cord-005646-xhx9pzhj 60 21 ( ( -LRB- cord-005646-xhx9pzhj 60 22 P.Op P.Op NNP cord-005646-xhx9pzhj 60 23 ) ) -RRB- cord-005646-xhx9pzhj 60 24 , , , cord-005646-xhx9pzhj 60 25 malnutrition malnutrition NN cord-005646-xhx9pzhj 60 26 , , , cord-005646-xhx9pzhj 60 27 diagnosis diagnosis NN cord-005646-xhx9pzhj 60 28 , , , cord-005646-xhx9pzhj 60 29 length length NN cord-005646-xhx9pzhj 60 30 of of IN cord-005646-xhx9pzhj 60 31 stay stay NN cord-005646-xhx9pzhj 60 32 , , , cord-005646-xhx9pzhj 60 33 PRISM prism NN cord-005646-xhx9pzhj 60 34 score score NN cord-005646-xhx9pzhj 60 35 and and CC cord-005646-xhx9pzhj 60 36 outcome outcome NN cord-005646-xhx9pzhj 60 37 . . . cord-005646-xhx9pzhj 61 1 Student student NN cord-005646-xhx9pzhj 61 2 test test NN cord-005646-xhx9pzhj 61 3 , , , cord-005646-xhx9pzhj 61 4 Mann Mann NNP cord-005646-xhx9pzhj 61 5 - - HYPH cord-005646-xhx9pzhj 61 6 Whitney Whitney NNP cord-005646-xhx9pzhj 61 7 or or CC cord-005646-xhx9pzhj 61 8 Wileoxon Wileoxon NNP cord-005646-xhx9pzhj 61 9 were be VBD cord-005646-xhx9pzhj 61 10 performed perform VBN cord-005646-xhx9pzhj 61 11 for for IN cord-005646-xhx9pzhj 61 12 univariate univariate JJ cord-005646-xhx9pzhj 61 13 analysis analysis NN cord-005646-xhx9pzhj 61 14 . . . cord-005646-xhx9pzhj 62 1 Fisher Fisher NNP cord-005646-xhx9pzhj 62 2 Exact Exact NNP cord-005646-xhx9pzhj 62 3 test test NN cord-005646-xhx9pzhj 62 4 or or CC cord-005646-xhx9pzhj 62 5 Chi Chi NNP cord-005646-xhx9pzhj 62 6 square square NNP cord-005646-xhx9pzhj 62 7 for for IN cord-005646-xhx9pzhj 62 8 dicotomic dicotomic JJ cord-005646-xhx9pzhj 62 9 variables variable NNS cord-005646-xhx9pzhj 62 10 . . . cord-005646-xhx9pzhj 63 1 Risk risk NN cord-005646-xhx9pzhj 63 2 group group NN cord-005646-xhx9pzhj 63 3 analysis analysis NN cord-005646-xhx9pzhj 63 4 was be VBD cord-005646-xhx9pzhj 63 5 performed perform VBN cord-005646-xhx9pzhj 63 6 by by IN cord-005646-xhx9pzhj 63 7 logistic logistic JJ cord-005646-xhx9pzhj 63 8 regression regression NN cord-005646-xhx9pzhj 63 9 , , , cord-005646-xhx9pzhj 63 10 odds odd NNS cord-005646-xhx9pzhj 63 11 ratio ratio NN cord-005646-xhx9pzhj 63 12 and and CC cord-005646-xhx9pzhj 63 13 95 95 CD cord-005646-xhx9pzhj 63 14 % % NN cord-005646-xhx9pzhj 63 15 confidence confidence NN cord-005646-xhx9pzhj 63 16 interval interval NN cord-005646-xhx9pzhj 63 17 . . . cord-005646-xhx9pzhj 64 1 Results result NNS cord-005646-xhx9pzhj 64 2 : : : cord-005646-xhx9pzhj 65 1 650 650 CD cord-005646-xhx9pzhj 65 2 patients patient NNS cord-005646-xhx9pzhj 65 3 entered enter VBD cord-005646-xhx9pzhj 65 4 the the DT cord-005646-xhx9pzhj 65 5 study study NN cord-005646-xhx9pzhj 65 6 . . . cord-005646-xhx9pzhj 66 1 Mean mean JJ cord-005646-xhx9pzhj 66 2 age age NN cord-005646-xhx9pzhj 66 3 was be VBD cord-005646-xhx9pzhj 66 4 47.6 47.6 CD cord-005646-xhx9pzhj 66 5 months month NNS cord-005646-xhx9pzhj 66 6 ( ( -LRB- cord-005646-xhx9pzhj 66 7 DS DS NNP cord-005646-xhx9pzhj 66 8 hh¢ hh¢ NNP cord-005646-xhx9pzhj 66 9 # # $ cord-005646-xhx9pzhj 66 10 60 60 CD cord-005646-xhx9pzhj 66 11 ) ) -RRB- cord-005646-xhx9pzhj 66 12 and and CC cord-005646-xhx9pzhj 66 13 median median NN cord-005646-xhx9pzhj 66 14 18 18 CD cord-005646-xhx9pzhj 66 15 months month NNS cord-005646-xhx9pzhj 66 16 . . . cord-005646-xhx9pzhj 67 1 We -PRON- PRP cord-005646-xhx9pzhj 67 2 found find VBD cord-005646-xhx9pzhj 67 3 significant significant JJ cord-005646-xhx9pzhj 67 4 statistical statistical JJ cord-005646-xhx9pzhj 67 5 differences difference NNS cord-005646-xhx9pzhj 67 6 in in IN cord-005646-xhx9pzhj 67 7 calculated calculate VBN cord-005646-xhx9pzhj 67 8 , , , cord-005646-xhx9pzhj 67 9 is be VBZ cord-005646-xhx9pzhj 67 10 observed observe VBN cord-005646-xhx9pzhj 67 11 mortality mortality NN cord-005646-xhx9pzhj 67 12 rate rate NN cord-005646-xhx9pzhj 67 13 comparing compare VBG cord-005646-xhx9pzhj 67 14 malnourished malnourish VBN cord-005646-xhx9pzhj 67 15 with with IN cord-005646-xhx9pzhj 67 16 euthrofic euthrofic JJ cord-005646-xhx9pzhj 67 17 patients patient NNS cord-005646-xhx9pzhj 67 18 ; ; : cord-005646-xhx9pzhj 67 19 Mechanical mechanical JJ cord-005646-xhx9pzhj 67 20 ventilated ventilate VBN cord-005646-xhx9pzhj 67 21 ( ( -LRB- cord-005646-xhx9pzhj 67 22 MV MV NNP cord-005646-xhx9pzhj 67 23 ) ) -RRB- cord-005646-xhx9pzhj 67 24 with with IN cord-005646-xhx9pzhj 67 25 non non JJ cord-005646-xhx9pzhj 67 26 MV MV NNP cord-005646-xhx9pzhj 67 27 patients patient NNS cord-005646-xhx9pzhj 67 28 . . . cord-005646-xhx9pzhj 68 1 No no DT cord-005646-xhx9pzhj 68 2 differences difference NNS cord-005646-xhx9pzhj 68 3 in in IN cord-005646-xhx9pzhj 68 4 ter ter NNP cord-005646-xhx9pzhj 68 5 ~,h ~,h NN cord-005646-xhx9pzhj 68 6 of of IN cord-005646-xhx9pzhj 68 7 stay stay NN cord-005646-xhx9pzhj 68 8 or or CC cord-005646-xhx9pzhj 68 9 di~ di~ NN cord-005646-xhx9pzhj 68 10 noses nose NNS cord-005646-xhx9pzhj 68 11 were be VBD cord-005646-xhx9pzhj 68 12 found find VBN cord-005646-xhx9pzhj 68 13 . . . cord-005646-xhx9pzhj 68 14 _SP cord-005646-xhx9pzhj 69 1 Effect effect NN cord-005646-xhx9pzhj 69 2 of of IN cord-005646-xhx9pzhj 69 3 the the DT cord-005646-xhx9pzhj 69 4 UN UN NNP cord-005646-xhx9pzhj 69 5 Sanctions Sanctions NNP cord-005646-xhx9pzhj 69 6 on on IN cord-005646-xhx9pzhj 69 7 the the DT cord-005646-xhx9pzhj 69 8 Morbidity Morbidity NNP cord-005646-xhx9pzhj 69 9 rate rate NN cord-005646-xhx9pzhj 69 10 araong araong NN cord-005646-xhx9pzhj 70 1 the the DT cord-005646-xhx9pzhj 70 2 iraqi iraqi JJ cord-005646-xhx9pzhj 70 3 small small JJ cord-005646-xhx9pzhj 70 4 children child NNS cord-005646-xhx9pzhj 70 5 ( ( -LRB- cord-005646-xhx9pzhj 70 6 below below IN cord-005646-xhx9pzhj 70 7 3 3 CD cord-005646-xhx9pzhj 70 8 years year NNS cord-005646-xhx9pzhj 70 9 old old JJ cord-005646-xhx9pzhj 70 10 of of IN cord-005646-xhx9pzhj 70 11 age age NN cord-005646-xhx9pzhj 70 12 ) ) -RRB- cord-005646-xhx9pzhj 70 13 in in IN cord-005646-xhx9pzhj 70 14 Bagdad Bagdad NNP cord-005646-xhx9pzhj 70 15 . . . cord-005646-xhx9pzhj 71 1 Abdulsamad Abdulsamad NNP cord-005646-xhx9pzhj 72 1 A.Abood A.Abood NNP cord-005646-xhx9pzhj 72 2 / / SYM cord-005646-xhx9pzhj 72 3 Institute Institute NNP cord-005646-xhx9pzhj 72 4 of of IN cord-005646-xhx9pzhj 72 5 Medical Medical NNP cord-005646-xhx9pzhj 72 6 Technology Technology NNP cord-005646-xhx9pzhj 72 7 , , , cord-005646-xhx9pzhj 72 8 Bagdad Bagdad NNP cord-005646-xhx9pzhj 72 9 . . . cord-005646-xhx9pzhj 73 1 Meningitis meningitis NN cord-005646-xhx9pzhj 73 2 is be VBZ cord-005646-xhx9pzhj 73 3 essentially essentially RB cord-005646-xhx9pzhj 73 4 a a DT cord-005646-xhx9pzhj 73 5 childhood childhood NN cord-005646-xhx9pzhj 73 6 disease disease NN cord-005646-xhx9pzhj 73 7 ( ( -LRB- cord-005646-xhx9pzhj 73 8 I i NN cord-005646-xhx9pzhj 73 9 ) ) -RRB- cord-005646-xhx9pzhj 73 10 . . . cord-005646-xhx9pzhj 74 1 The the DT cord-005646-xhx9pzhj 74 2 risk risk NN cord-005646-xhx9pzhj 74 3 of of IN cord-005646-xhx9pzhj 74 4 infection infection NN cord-005646-xhx9pzhj 74 5 are be VBP cord-005646-xhx9pzhj 74 6 increased increase VBN cord-005646-xhx9pzhj 74 7 by by IN cord-005646-xhx9pzhj 74 8 powerty powerty NN cord-005646-xhx9pzhj 74 9 and and CC cord-005646-xhx9pzhj 74 10 overcrowding overcrowding NN cord-005646-xhx9pzhj 74 11 ( ( -LRB- cord-005646-xhx9pzhj 74 12 7 7 CD cord-005646-xhx9pzhj 74 13 ) ) -RRB- cord-005646-xhx9pzhj 74 14 . . . cord-005646-xhx9pzhj 75 1 The the DT cord-005646-xhx9pzhj 75 2 impah'ed impah'ed JJ cord-005646-xhx9pzhj 75 3 Immunity immunity NN cord-005646-xhx9pzhj 75 4 may may MD cord-005646-xhx9pzhj 75 5 be be VB cord-005646-xhx9pzhj 75 6 an an DT cord-005646-xhx9pzhj 75 7 important important JJ cord-005646-xhx9pzhj 75 8 pathogenic pathogenic JJ cord-005646-xhx9pzhj 75 9 factor factor NN cord-005646-xhx9pzhj 75 10 underlying underlie VBG cord-005646-xhx9pzhj 75 11 the the DT cord-005646-xhx9pzhj 75 12 susceptibility susceptibility NN cord-005646-xhx9pzhj 75 13 to to IN cord-005646-xhx9pzhj 75 14 infections infection NNS cord-005646-xhx9pzhj 75 15 in in IN cord-005646-xhx9pzhj 75 16 undernourished undernourished JJ cord-005646-xhx9pzhj 75 17 subjects subject NNS cord-005646-xhx9pzhj 75 18 ( ( -LRB- cord-005646-xhx9pzhj 75 19 5 5 CD cord-005646-xhx9pzhj 75 20 ) ) -RRB- cord-005646-xhx9pzhj 75 21 . . . cord-005646-xhx9pzhj 76 1 In in IN cord-005646-xhx9pzhj 76 2 general general JJ cord-005646-xhx9pzhj 76 3 , , , cord-005646-xhx9pzhj 76 4 malnutrition malnutrition NN cord-005646-xhx9pzhj 76 5 is be VBZ cord-005646-xhx9pzhj 76 6 a a DT cord-005646-xhx9pzhj 76 7 man man NN cord-005646-xhx9pzhj 76 8 made make VBN cord-005646-xhx9pzhj 76 9 disease disease NN cord-005646-xhx9pzhj 76 10 and and CC cord-005646-xhx9pzhj 76 11 it -PRON- PRP cord-005646-xhx9pzhj 76 12 begins begin VBZ cord-005646-xhx9pzhj 76 13 quite quite RB cord-005646-xhx9pzhj 76 14 in in IN cord-005646-xhx9pzhj 76 15 the the DT cord-005646-xhx9pzhj 76 16 womb womb NN cord-005646-xhx9pzhj 76 17 and and CC cord-005646-xhx9pzhj 76 18 ends end VBZ cord-005646-xhx9pzhj 76 19 in in IN cord-005646-xhx9pzhj 76 20 the the DT cord-005646-xhx9pzhj 76 21 grave grave NN cord-005646-xhx9pzhj 76 22 ( ( -LRB- cord-005646-xhx9pzhj 76 23 I i NN cord-005646-xhx9pzhj 76 24 ) ) -RRB- cord-005646-xhx9pzhj 76 25 . . . cord-005646-xhx9pzhj 77 1 1918 1918 CD cord-005646-xhx9pzhj 77 2 small small JJ cord-005646-xhx9pzhj 77 3 children child NNS cord-005646-xhx9pzhj 77 4 , , , cord-005646-xhx9pzhj 77 5 below below IN cord-005646-xhx9pzhj 77 6 3 3 CD cord-005646-xhx9pzhj 77 7 years year NNS cord-005646-xhx9pzhj 77 8 of of IN cord-005646-xhx9pzhj 77 9 age age NN cord-005646-xhx9pzhj 77 10 were be VBD cord-005646-xhx9pzhj 77 11 admitted admit VBN cord-005646-xhx9pzhj 77 12 to to IN cord-005646-xhx9pzhj 77 13 the the DT cord-005646-xhx9pzhj 77 14 pediatric pediatric JJ cord-005646-xhx9pzhj 77 15 Hospital Hospital NNP cord-005646-xhx9pzhj 77 16 in in IN cord-005646-xhx9pzhj 77 17 Washash Washash NNP cord-005646-xhx9pzhj 77 18 with with IN cord-005646-xhx9pzhj 77 19 meningitis meningitis NN cord-005646-xhx9pzhj 77 20 over over IN cord-005646-xhx9pzhj 77 21 4 4 CD cord-005646-xhx9pzhj 77 22 cold cold JJ cord-005646-xhx9pzhj 77 23 months month NNS cord-005646-xhx9pzhj 77 24 in in IN cord-005646-xhx9pzhj 77 25 I994 I994 NNP cord-005646-xhx9pzhj 77 26 , , , cord-005646-xhx9pzhj 77 27 in in IN cord-005646-xhx9pzhj 77 28 contrast contrast NN cord-005646-xhx9pzhj 77 29 to to IN cord-005646-xhx9pzhj 77 30 only only RB cord-005646-xhx9pzhj 77 31 176 176 CD cord-005646-xhx9pzhj 77 32 child child NN cord-005646-xhx9pzhj 77 33 admitted admit VBN cord-005646-xhx9pzhj 77 34 with with IN cord-005646-xhx9pzhj 77 35 meningitis meningitis NN cord-005646-xhx9pzhj 77 36 over over IN cord-005646-xhx9pzhj 77 37 the the DT cord-005646-xhx9pzhj 77 38 same same JJ cord-005646-xhx9pzhj 77 39 period period NN cord-005646-xhx9pzhj 77 40 in1989 in1989 NNP cord-005646-xhx9pzhj 77 41 . . . cord-005646-xhx9pzhj 78 1 All all DT cord-005646-xhx9pzhj 78 2 of of IN cord-005646-xhx9pzhj 78 3 the the DT cord-005646-xhx9pzhj 78 4 children child NNS cord-005646-xhx9pzhj 78 5 who who WP cord-005646-xhx9pzhj 78 6 admitted admit VBD cord-005646-xhx9pzhj 78 7 in in IN cord-005646-xhx9pzhj 78 8 1994 1994 CD cord-005646-xhx9pzhj 78 9 were be VBD cord-005646-xhx9pzhj 78 10 frankly frankly RB cord-005646-xhx9pzhj 78 11 undernourished undernourished JJ cord-005646-xhx9pzhj 78 12 , , , cord-005646-xhx9pzhj 78 13 45 45 CD cord-005646-xhx9pzhj 78 14 % % NN cord-005646-xhx9pzhj 78 15 of of IN cord-005646-xhx9pzhj 78 16 them -PRON- PRP cord-005646-xhx9pzhj 78 17 were be VBD cord-005646-xhx9pzhj 78 18 infected infect VBN cord-005646-xhx9pzhj 78 19 with with IN cord-005646-xhx9pzhj 78 20 Enterobacteriae Enterobacteriae NNP cord-005646-xhx9pzhj 78 21 , , , cord-005646-xhx9pzhj 78 22 because because IN cord-005646-xhx9pzhj 78 23 they -PRON- PRP cord-005646-xhx9pzhj 78 24 were be VBD cord-005646-xhx9pzhj 78 25 exposed expose VBN cord-005646-xhx9pzhj 78 26 to to IN cord-005646-xhx9pzhj 78 27 faulty faulty JJ cord-005646-xhx9pzhj 78 28 Hygiene hygiene NN cord-005646-xhx9pzhj 78 29 and and CC cord-005646-xhx9pzhj 78 30 lack lack NN cord-005646-xhx9pzhj 78 31 of of IN cord-005646-xhx9pzhj 78 32 Asepsis Asepsis NNP cord-005646-xhx9pzhj 78 33 . . . cord-005646-xhx9pzhj 79 1 These these DT cord-005646-xhx9pzhj 79 2 facts fact NNS cord-005646-xhx9pzhj 79 3 showed show VBD cord-005646-xhx9pzhj 79 4 precisely precisely RB cord-005646-xhx9pzhj 79 5 that that IN cord-005646-xhx9pzhj 79 6 our -PRON- PRP$ cord-005646-xhx9pzhj 79 7 small small JJ cord-005646-xhx9pzhj 79 8 children child NNS cord-005646-xhx9pzhj 79 9 had have VBD cord-005646-xhx9pzhj 79 10 suffered suffer VBN cord-005646-xhx9pzhj 79 11 at at IN cord-005646-xhx9pzhj 79 12 most most JJS cord-005646-xhx9pzhj 79 13 from from IN cord-005646-xhx9pzhj 79 14 the the DT cord-005646-xhx9pzhj 79 15 UN UN NNP cord-005646-xhx9pzhj 79 16 _ _ NNP cord-005646-xhx9pzhj 79 17 Sanctions Sanctions NNP cord-005646-xhx9pzhj 79 18 against against IN cord-005646-xhx9pzhj 79 19 Iraq Iraq NNP cord-005646-xhx9pzhj 79 20 , , , cord-005646-xhx9pzhj 79 21 because because IN cord-005646-xhx9pzhj 79 22 of of IN cord-005646-xhx9pzhj 79 23 food food NN cord-005646-xhx9pzhj 79 24 , , , cord-005646-xhx9pzhj 79 25 milk milk NN cord-005646-xhx9pzhj 79 26 and and CC cord-005646-xhx9pzhj 79 27 drug drug NN cord-005646-xhx9pzhj 79 28 shortage shortage NN cord-005646-xhx9pzhj 79 29 , , , cord-005646-xhx9pzhj 79 30 since since IN cord-005646-xhx9pzhj 79 31 4 4 CD cord-005646-xhx9pzhj 79 32 years year NNS cord-005646-xhx9pzhj 79 33 which which WDT cord-005646-xhx9pzhj 79 34 had have VBD cord-005646-xhx9pzhj 79 35 resulted result VBN cord-005646-xhx9pzhj 79 36 a a DT cord-005646-xhx9pzhj 79 37 severe severe JJ cord-005646-xhx9pzhj 79 38 undernutrition undernutrition NN cord-005646-xhx9pzhj 79 39 among among IN cord-005646-xhx9pzhj 79 40 them -PRON- PRP cord-005646-xhx9pzhj 79 41 , , , cord-005646-xhx9pzhj 79 42 which which WDT cord-005646-xhx9pzhj 79 43 impaired impair VBD cord-005646-xhx9pzhj 79 44 their -PRON- PRP$ cord-005646-xhx9pzhj 79 45 immune immune JJ cord-005646-xhx9pzhj 79 46 status status NN cord-005646-xhx9pzhj 79 47 . . . cord-005646-xhx9pzhj 80 1 M M NNP cord-005646-xhx9pzhj 80 2 Wells Wells NNP cord-005646-xhx9pzhj 80 3 , , , cord-005646-xhx9pzhj 80 4 OF of IN cord-005646-xhx9pzhj 80 5 Riera Riera NNP cord-005646-xhx9pzhj 80 6 - - HYPH cord-005646-xhx9pzhj 80 7 Fanego Fanego NNP cord-005646-xhx9pzhj 80 8 , , , cord-005646-xhx9pzhj 80 9 J J NNP cord-005646-xhx9pzhj 80 10 Lipman Lipman NNP cord-005646-xhx9pzhj 80 11 . . . cord-005646-xhx9pzhj 81 1 Baragwanath Baragwanath NNP cord-005646-xhx9pzhj 81 2 Intensive Intensive NNP cord-005646-xhx9pzhj 81 3 Care Care NNP cord-005646-xhx9pzhj 81 4 Unit Unit NNP cord-005646-xhx9pzhj 81 5 , , , cord-005646-xhx9pzhj 81 6 University University NNP cord-005646-xhx9pzhj 81 7 of of IN cord-005646-xhx9pzhj 81 8 the the DT cord-005646-xhx9pzhj 81 9 Witwatersrand Witwatersrand NNP cord-005646-xhx9pzhj 81 10 , , , cord-005646-xhx9pzhj 81 11 South South NNP cord-005646-xhx9pzhj 81 12 Africa Africa NNP cord-005646-xhx9pzhj 81 13 . . . cord-005646-xhx9pzhj 82 1 Background background NN cord-005646-xhx9pzhj 83 1 The the DT cord-005646-xhx9pzhj 83 2 use use NN cord-005646-xhx9pzhj 83 3 of of IN cord-005646-xhx9pzhj 83 4 PRISM prism NN cord-005646-xhx9pzhj 83 5 or or CC cord-005646-xhx9pzhj 83 6 other other JJ cord-005646-xhx9pzhj 83 7 scoring score VBG cord-005646-xhx9pzhj 83 8 systems system NNS cord-005646-xhx9pzhj 83 9 in in IN cord-005646-xhx9pzhj 83 10 the the DT cord-005646-xhx9pzhj 83 11 ICU ICU NNP cord-005646-xhx9pzhj 83 12 is be VBZ cord-005646-xhx9pzhj 83 13 of of IN cord-005646-xhx9pzhj 83 14 great great JJ cord-005646-xhx9pzhj 83 15 importance importance NN cord-005646-xhx9pzhj 83 16 for for IN cord-005646-xhx9pzhj 83 17 evaluating evaluate VBG cord-005646-xhx9pzhj 83 18 the the DT cord-005646-xhx9pzhj 83 19 efficacy efficacy NN cord-005646-xhx9pzhj 83 20 and and CC cord-005646-xhx9pzhj 83 21 efficiency efficiency NN cord-005646-xhx9pzhj 83 22 of of IN cord-005646-xhx9pzhj 83 23 a a DT cord-005646-xhx9pzhj 83 24 particular particular JJ cord-005646-xhx9pzhj 83 25 ICU ICU NNP cord-005646-xhx9pzhj 83 26 , , , cord-005646-xhx9pzhj 83 27 The the DT cord-005646-xhx9pzhj 83 28 PRISM prism NN cord-005646-xhx9pzhj 83 29 score score NN cord-005646-xhx9pzhj 83 30 was be VBD cord-005646-xhx9pzhj 83 31 developed develop VBN cord-005646-xhx9pzhj 83 32 and and CC cord-005646-xhx9pzhj 83 33 validated validate VBN cord-005646-xhx9pzhj 83 34 in in IN cord-005646-xhx9pzhj 83 35 the the DT cord-005646-xhx9pzhj 83 36 USA USA NNP cord-005646-xhx9pzhj 83 37 and and CC cord-005646-xhx9pzhj 83 38 Europe Europe NNP cord-005646-xhx9pzhj 83 39 but but CC cord-005646-xhx9pzhj 83 40 has have VBZ cord-005646-xhx9pzhj 83 41 recently recently RB cord-005646-xhx9pzhj 83 42 been be VBN cord-005646-xhx9pzhj 83 43 shown show VBN cord-005646-xhx9pzhj 83 44 to to TO cord-005646-xhx9pzhj 83 45 be be VB cord-005646-xhx9pzhj 83 46 inaccurate inaccurate JJ cord-005646-xhx9pzhj 83 47 in in IN cord-005646-xhx9pzhj 83 48 a a DT cord-005646-xhx9pzhj 83 49 South south JJ cord-005646-xhx9pzhj 83 50 American american JJ cord-005646-xhx9pzhj 83 51 population population NN cord-005646-xhx9pzhj 83 52 , , , cord-005646-xhx9pzhj 83 53 a a DT cord-005646-xhx9pzhj 83 54 South south JJ cord-005646-xhx9pzhj 83 55 African african JJ cord-005646-xhx9pzhj 83 56 population population NN cord-005646-xhx9pzhj 83 57 as as RB cord-005646-xhx9pzhj 83 58 well well RB cord-005646-xhx9pzhj 83 59 as as IN cord-005646-xhx9pzhj 83 60 several several JJ cord-005646-xhx9pzhj 83 61 European european JJ cord-005646-xhx9pzhj 83 62 studies study NNS cord-005646-xhx9pzhj 83 63 . . . cord-005646-xhx9pzhj 84 1 Part part NN cord-005646-xhx9pzhj 84 2 of of IN cord-005646-xhx9pzhj 84 3 the the DT cord-005646-xhx9pzhj 84 4 poor poor JJ cord-005646-xhx9pzhj 84 5 performance performance NN cord-005646-xhx9pzhj 84 6 of of IN cord-005646-xhx9pzhj 84 7 the the DT cord-005646-xhx9pzhj 84 8 PRISM prism NN cord-005646-xhx9pzhj 84 9 score score NN cord-005646-xhx9pzhj 84 10 is be VBZ cord-005646-xhx9pzhj 84 11 as as IN cord-005646-xhx9pzhj 84 12 a a DT cord-005646-xhx9pzhj 84 13 result result NN cord-005646-xhx9pzhj 84 14 of of IN cord-005646-xhx9pzhj 84 15 differences difference NNS cord-005646-xhx9pzhj 84 16 in in IN cord-005646-xhx9pzhj 84 17 the the DT cord-005646-xhx9pzhj 84 18 case case NN cord-005646-xhx9pzhj 84 19 mix mix NN cord-005646-xhx9pzhj 84 20 between between IN cord-005646-xhx9pzhj 84 21 the the DT cord-005646-xhx9pzhj 84 22 reference reference NN cord-005646-xhx9pzhj 84 23 population population NN cord-005646-xhx9pzhj 84 24 and and CC cord-005646-xhx9pzhj 84 25 other other JJ cord-005646-xhx9pzhj 84 26 paediatric paediatric JJ cord-005646-xhx9pzhj 84 27 ICUs icu NNS cord-005646-xhx9pzhj 84 28 . . . cord-005646-xhx9pzhj 85 1 Since since IN cord-005646-xhx9pzhj 85 2 scoring score VBG cord-005646-xhx9pzhj 85 3 systems system NNS cord-005646-xhx9pzhj 85 4 should should MD cord-005646-xhx9pzhj 85 5 generally generally RB cord-005646-xhx9pzhj 85 6 be be VB cord-005646-xhx9pzhj 85 7 used use VBN cord-005646-xhx9pzhj 85 8 only only RB cord-005646-xhx9pzhj 85 9 in in IN cord-005646-xhx9pzhj 85 10 populations population NNS cord-005646-xhx9pzhj 85 11 similar similar JJ cord-005646-xhx9pzhj 85 12 to to IN cord-005646-xhx9pzhj 85 13 the the DT cord-005646-xhx9pzhj 85 14 reference reference NN cord-005646-xhx9pzhj 85 15 population population NN cord-005646-xhx9pzhj 85 16 from from IN cord-005646-xhx9pzhj 85 17 which which WDT cord-005646-xhx9pzhj 85 18 the the DT cord-005646-xhx9pzhj 85 19 prediction prediction NN cord-005646-xhx9pzhj 85 20 model model NN cord-005646-xhx9pzhj 85 21 was be VBD cord-005646-xhx9pzhj 85 22 developed develop VBN cord-005646-xhx9pzhj 85 23 , , , cord-005646-xhx9pzhj 85 24 a a DT cord-005646-xhx9pzhj 85 25 modification modification NN cord-005646-xhx9pzhj 85 26 of of IN cord-005646-xhx9pzhj 85 27 the the DT cord-005646-xhx9pzhj 85 28 PRISM prism NN cord-005646-xhx9pzhj 85 29 score score NN cord-005646-xhx9pzhj 85 30 is be VBZ cord-005646-xhx9pzhj 85 31 necessary necessary JJ cord-005646-xhx9pzhj 85 32 to to TO cord-005646-xhx9pzhj 85 33 improve improve VB cord-005646-xhx9pzhj 85 34 its -PRON- PRP$ cord-005646-xhx9pzhj 85 35 discriminatory discriminatory JJ cord-005646-xhx9pzhj 85 36 ability ability NN cord-005646-xhx9pzhj 85 37 in in IN cord-005646-xhx9pzhj 85 38 a a DT cord-005646-xhx9pzhj 85 39 wide wide JJ cord-005646-xhx9pzhj 85 40 range range NN cord-005646-xhx9pzhj 85 41 of of IN cord-005646-xhx9pzhj 85 42 patient patient JJ cord-005646-xhx9pzhj 85 43 groups group NNS cord-005646-xhx9pzhj 85 44 , , , cord-005646-xhx9pzhj 85 45 Aim aim VB cord-005646-xhx9pzhj 85 46 To to TO cord-005646-xhx9pzhj 85 47 improve improve VB cord-005646-xhx9pzhj 85 48 the the DT cord-005646-xhx9pzhj 85 49 predictive predictive JJ cord-005646-xhx9pzhj 85 50 power power NN cord-005646-xhx9pzhj 85 51 of of IN cord-005646-xhx9pzhj 85 52 the the DT cord-005646-xhx9pzhj 85 53 PRISM prism NN cord-005646-xhx9pzhj 85 54 score score NN cord-005646-xhx9pzhj 85 55 in in IN cord-005646-xhx9pzhj 85 56 a a DT cord-005646-xhx9pzhj 85 57 South south JJ cord-005646-xhx9pzhj 85 58 African african JJ cord-005646-xhx9pzhj 85 59 paediatdc paediatdc NN cord-005646-xhx9pzhj 85 60 ICU ICU NNP cord-005646-xhx9pzhj 85 61 population population NN cord-005646-xhx9pzhj 85 62 . . . cord-005646-xhx9pzhj 86 1 Patients patient NNS cord-005646-xhx9pzhj 86 2 & & CC cord-005646-xhx9pzhj 86 3 Methods method NNS cord-005646-xhx9pzhj 87 1 We -PRON- PRP cord-005646-xhx9pzhj 87 2 analysed analyse VBD cord-005646-xhx9pzhj 87 3 PRISM PRISM NNP cord-005646-xhx9pzhj 87 4 , , , cord-005646-xhx9pzhj 87 5 demographic demographic JJ cord-005646-xhx9pzhj 87 6 and and CC cord-005646-xhx9pzhj 87 7 clinical clinical JJ cord-005646-xhx9pzhj 87 8 data datum NNS cord-005646-xhx9pzhj 87 9 collected collect VBN cord-005646-xhx9pzhj 87 10 prospectively prospectively RB cord-005646-xhx9pzhj 87 11 from from IN cord-005646-xhx9pzhj 87 12 1528 1528 CD cord-005646-xhx9pzhj 87 13 consecutive consecutive JJ cord-005646-xhx9pzhj 87 14 paediatrie paediatrie NNS cord-005646-xhx9pzhj 87 15 ICU ICU NNP cord-005646-xhx9pzhj 87 16 admissions admission NNS cord-005646-xhx9pzhj 87 17 . . . cord-005646-xhx9pzhj 88 1 The the DT cord-005646-xhx9pzhj 88 2 prediction prediction NN cord-005646-xhx9pzhj 88 3 of of IN cord-005646-xhx9pzhj 88 4 actual actual JJ cord-005646-xhx9pzhj 88 5 mortality mortality NN cord-005646-xhx9pzhj 88 6 by by IN cord-005646-xhx9pzhj 88 7 PRISM PRISM NNP cord-005646-xhx9pzhj 88 8 was be VBD cord-005646-xhx9pzhj 88 9 evaluated evaluate VBN cord-005646-xhx9pzhj 88 10 by by IN cord-005646-xhx9pzhj 88 11 standard standard JJ cord-005646-xhx9pzhj 88 12 statistical statistical JJ cord-005646-xhx9pzhj 88 13 methodology methodology NN cord-005646-xhx9pzhj 88 14 ( ( -LRB- cord-005646-xhx9pzhj 88 15 goodness goodness NN cord-005646-xhx9pzhj 88 16 - - HYPH cord-005646-xhx9pzhj 88 17 of of IN cord-005646-xhx9pzhj 88 18 - - HYPH cord-005646-xhx9pzhj 88 19 fit fit JJ cord-005646-xhx9pzhj 88 20 test test NN cord-005646-xhx9pzhj 88 21 and and CC cord-005646-xhx9pzhj 88 22 receiver receiver NN cord-005646-xhx9pzhj 88 23 operating operating NN cord-005646-xhx9pzhj 88 24 characteristic characteristic NN cord-005646-xhx9pzhj 88 25 ( ( -LRB- cord-005646-xhx9pzhj 88 26 ROC ROC NNP cord-005646-xhx9pzhj 88 27 ) ) -RRB- cord-005646-xhx9pzhj 88 28 analysis analysis NN cord-005646-xhx9pzhj 88 29 ) ) -RRB- cord-005646-xhx9pzhj 88 30 , , , cord-005646-xhx9pzhj 88 31 The the DT cord-005646-xhx9pzhj 88 32 components component NNS cord-005646-xhx9pzhj 88 33 of of IN cord-005646-xhx9pzhj 88 34 the the DT cord-005646-xhx9pzhj 88 35 PRISM PRISM NNP cord-005646-xhx9pzhj 88 36 logistic logistic JJ cord-005646-xhx9pzhj 88 37 regression regression NN cord-005646-xhx9pzhj 88 38 equation equation NN cord-005646-xhx9pzhj 88 39 ( ( -LRB- cord-005646-xhx9pzhj 88 40 PRISM prism NN cord-005646-xhx9pzhj 88 41 score score NN cord-005646-xhx9pzhj 88 42 , , , cord-005646-xhx9pzhj 88 43 operative operative JJ cord-005646-xhx9pzhj 88 44 status status NN cord-005646-xhx9pzhj 88 45 and and CC cord-005646-xhx9pzhj 88 46 age age NN cord-005646-xhx9pzhj 88 47 ) ) -RRB- cord-005646-xhx9pzhj 88 48 and and CC cord-005646-xhx9pzhj 88 49 the the DT cord-005646-xhx9pzhj 88 50 14 14 CD cord-005646-xhx9pzhj 88 51 physiological physiological JJ cord-005646-xhx9pzhj 88 52 variables variable NNS cord-005646-xhx9pzhj 88 53 making make VBG cord-005646-xhx9pzhj 88 54 up up RP cord-005646-xhx9pzhj 88 55 the the DT cord-005646-xhx9pzhj 88 56 PRISM prism NN cord-005646-xhx9pzhj 88 57 score score NN cord-005646-xhx9pzhj 88 58 in in IN cord-005646-xhx9pzhj 88 59 addition addition NN cord-005646-xhx9pzhj 88 60 10 10 CD cord-005646-xhx9pzhj 88 61 new new JJ cord-005646-xhx9pzhj 88 62 variables variable NNS cord-005646-xhx9pzhj 88 63 analysed analyse VBN cord-005646-xhx9pzhj 88 64 ( ( -LRB- cord-005646-xhx9pzhj 88 65 nutritional nutritional JJ cord-005646-xhx9pzhj 88 66 index index NN cord-005646-xhx9pzhj 88 67 , , , cord-005646-xhx9pzhj 88 68 the the DT cord-005646-xhx9pzhj 88 69 need need NN cord-005646-xhx9pzhj 88 70 for for IN cord-005646-xhx9pzhj 88 71 inotropes inotrope NNS cord-005646-xhx9pzhj 88 72 and and CC cord-005646-xhx9pzhj 88 73 institution institution NN cord-005646-xhx9pzhj 88 74 of of IN cord-005646-xhx9pzhj 88 75 mechanical mechanical JJ cord-005646-xhx9pzhj 88 76 ventilation ventilation NN cord-005646-xhx9pzhj 88 77 ) ) -RRB- cord-005646-xhx9pzhj 88 78 were be VBD cord-005646-xhx9pzhj 88 79 subjected subject VBN cord-005646-xhx9pzhj 88 80 to to IN cord-005646-xhx9pzhj 88 81 discriminant discriminant JJ cord-005646-xhx9pzhj 88 82 analysis analysis NN cord-005646-xhx9pzhj 88 83 to to TO cord-005646-xhx9pzhj 88 84 determine determine VB cord-005646-xhx9pzhj 88 85 their -PRON- PRP$ cord-005646-xhx9pzhj 88 86 association association NN cord-005646-xhx9pzhj 88 87 with with IN cord-005646-xhx9pzhj 88 88 outcome outcome NN cord-005646-xhx9pzhj 88 89 . . . cord-005646-xhx9pzhj 89 1 Results result NNS cord-005646-xhx9pzhj 90 1 The the DT cord-005646-xhx9pzhj 90 2 goodness goodness NN cord-005646-xhx9pzhj 90 3 - - HYPH cord-005646-xhx9pzhj 90 4 of of IN cord-005646-xhx9pzhj 90 5 - - HYPH cord-005646-xhx9pzhj 90 6 fit fit JJ cord-005646-xhx9pzhj 90 7 test test NN cord-005646-xhx9pzhj 90 8 showed show VBD cord-005646-xhx9pzhj 90 9 a a DT cord-005646-xhx9pzhj 90 10 significant significant JJ cord-005646-xhx9pzhj 90 11 failure failure NN cord-005646-xhx9pzhj 90 12 of of IN cord-005646-xhx9pzhj 90 13 PRISM prism NN cord-005646-xhx9pzhj 90 14 to to TO cord-005646-xhx9pzhj 90 15 accurately accurately RB cord-005646-xhx9pzhj 90 16 predict predict VB cord-005646-xhx9pzhj 90 17 mortality mortality NN cord-005646-xhx9pzhj 90 18 over over IN cord-005646-xhx9pzhj 90 19 a a DT cord-005646-xhx9pzhj 90 20 wide wide JJ cord-005646-xhx9pzhj 90 21 range range NN cord-005646-xhx9pzhj 90 22 of of IN cord-005646-xhx9pzhj 90 23 expected expect VBN cord-005646-xhx9pzhj 90 24 mortality mortality NN cord-005646-xhx9pzhj 90 25 ( ( -LRB- cord-005646-xhx9pzhj 90 26 Chi2[8 Chi2[8 NNP cord-005646-xhx9pzhj 90 27 ] ] -RRB- cord-005646-xhx9pzhj 90 28 = = NFP cord-005646-xhx9pzhj 91 1 195 195 CD cord-005646-xhx9pzhj 91 2 , , , cord-005646-xhx9pzhj 91 3 p p NN cord-005646-xhx9pzhj 91 4 = = SYM cord-005646-xhx9pzhj 91 5 0 0 CD cord-005646-xhx9pzhj 91 6 ) ) -RRB- cord-005646-xhx9pzhj 91 7 . . . cord-005646-xhx9pzhj 92 1 PRISM prism NN cord-005646-xhx9pzhj 92 2 underpredicted underpredicte VBD cord-005646-xhx9pzhj 92 3 mortality mortality NN cord-005646-xhx9pzhj 92 4 at at IN cord-005646-xhx9pzhj 92 5 lower low JJR cord-005646-xhx9pzhj 92 6 PRISM prism NN cord-005646-xhx9pzhj 92 7 scores score NNS cord-005646-xhx9pzhj 92 8 , , , cord-005646-xhx9pzhj 92 9 but but CC cord-005646-xhx9pzhj 92 10 overpredicted overpredicted JJ cord-005646-xhx9pzhj 92 11 mortality mortality NN cord-005646-xhx9pzhj 92 12 in in IN cord-005646-xhx9pzhj 92 13 patients patient NNS cord-005646-xhx9pzhj 92 14 with with IN cord-005646-xhx9pzhj 92 15 high high JJ cord-005646-xhx9pzhj 92 16 PRISMs prism NNS cord-005646-xhx9pzhj 92 17 . . . cord-005646-xhx9pzhj 93 1 Similarly similarly RB cord-005646-xhx9pzhj 93 2 ROC ROC NNP cord-005646-xhx9pzhj 93 3 anNysis anNysis NNP cord-005646-xhx9pzhj 93 4 indicated indicate VBD cord-005646-xhx9pzhj 93 5 apoor apoor NNP cord-005646-xhx9pzhj 93 6 predic predic NNP cord-005646-xhx9pzhj 93 7 ~ ~ NFP cord-005646-xhx9pzhj 93 8 Jve Jve NNP cord-005646-xhx9pzhj 93 9 power power NN cord-005646-xhx9pzhj 93 10 ( ( -LRB- cord-005646-xhx9pzhj 93 11 Az Az NNP cord-005646-xhx9pzhj 93 12 = = SYM cord-005646-xhx9pzhj 93 13 0.73 0.73 CD cord-005646-xhx9pzhj 93 14 ± ± CD cord-005646-xhx9pzhj 93 15 0.01 0.01 CD cord-005646-xhx9pzhj 93 16 ) ) -RRB- cord-005646-xhx9pzhj 93 17 , , , cord-005646-xhx9pzhj 93 18 with with IN cord-005646-xhx9pzhj 93 19 an an DT cord-005646-xhx9pzhj 93 20 area area NN cord-005646-xhx9pzhj 93 21 under under IN cord-005646-xhx9pzhj 93 22 the the DT cord-005646-xhx9pzhj 93 23 curve curve NN cord-005646-xhx9pzhj 93 24 significantly significantly RB cord-005646-xhx9pzhj 93 25 less less RBR cord-005646-xhx9pzhj 93 26 than than IN cord-005646-xhx9pzhj 93 27 that that DT cord-005646-xhx9pzhj 93 28 for for IN cord-005646-xhx9pzhj 93 29 the the DT cord-005646-xhx9pzhj 93 30 PRISM PRISM NNP cord-005646-xhx9pzhj 93 31 reference reference NN cord-005646-xhx9pzhj 93 32 population population NN cord-005646-xhx9pzhj 93 33 ( ( -LRB- cord-005646-xhx9pzhj 93 34 p p NN cord-005646-xhx9pzhj 93 35 = = SYM cord-005646-xhx9pzhj 93 36 0 0 CD cord-005646-xhx9pzhj 93 37 ) ) -RRB- cord-005646-xhx9pzhj 93 38 , , , cord-005646-xhx9pzhj 93 39 PRISM PRISM NNP cord-005646-xhx9pzhj 93 40 showed show VBD cord-005646-xhx9pzhj 93 41 equally equally RB cord-005646-xhx9pzhj 93 42 poor poor JJ cord-005646-xhx9pzhj 93 43 discriminatory discriminatory JJ cord-005646-xhx9pzhj 93 44 function function NN cord-005646-xhx9pzhj 93 45 at at IN cord-005646-xhx9pzhj 93 46 all all DT cord-005646-xhx9pzhj 93 47 age age NN cord-005646-xhx9pzhj 93 48 groups group NNS cord-005646-xhx9pzhj 93 49 and and CC cord-005646-xhx9pzhj 93 50 diagnosfic diagnosfic JJ cord-005646-xhx9pzhj 93 51 categories category NNS cord-005646-xhx9pzhj 93 52 . . . cord-005646-xhx9pzhj 93 53 ' ' '' cord-005646-xhx9pzhj 94 1 ~Mth ~Mth NNP cord-005646-xhx9pzhj 94 2 the the DT cord-005646-xhx9pzhj 94 3 addition addition NN cord-005646-xhx9pzhj 94 4 of of IN cord-005646-xhx9pzhj 94 5 an an DT cord-005646-xhx9pzhj 94 6 index index NN cord-005646-xhx9pzhj 94 7 of of IN cord-005646-xhx9pzhj 94 8 nutrifional nutrifional JJ cord-005646-xhx9pzhj 94 9 status status NN cord-005646-xhx9pzhj 94 10 ( ( -LRB- cord-005646-xhx9pzhj 94 11 proportional proportional JJ cord-005646-xhx9pzhj 94 12 weight weight NN cord-005646-xhx9pzhj 94 13 - - HYPH cord-005646-xhx9pzhj 94 14 far far JJ cord-005646-xhx9pzhj 94 15 - - HYPH cord-005646-xhx9pzhj 94 16 age age NN cord-005646-xhx9pzhj 94 17 ) ) -RRB- cord-005646-xhx9pzhj 94 18 , , , cord-005646-xhx9pzhj 94 19 and and CC cord-005646-xhx9pzhj 94 20 indicators indicator NNS cord-005646-xhx9pzhj 94 21 of of IN cord-005646-xhx9pzhj 94 22 early early JJ cord-005646-xhx9pzhj 94 23 respiratory respiratory JJ cord-005646-xhx9pzhj 94 24 and and CC cord-005646-xhx9pzhj 94 25 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 94 26 failure failure NN cord-005646-xhx9pzhj 94 27 to to IN cord-005646-xhx9pzhj 94 28 the the DT cord-005646-xhx9pzhj 94 29 logistic logistic JJ cord-005646-xhx9pzhj 94 30 regression regression NN cord-005646-xhx9pzhj 94 31 formula formula NN cord-005646-xhx9pzhj 94 32 , , , cord-005646-xhx9pzhj 94 33 and and CC cord-005646-xhx9pzhj 94 34 a a DT cord-005646-xhx9pzhj 94 35 recalibration recalibration NN cord-005646-xhx9pzhj 94 36 of of IN cord-005646-xhx9pzhj 94 37 the the DT cord-005646-xhx9pzhj 94 38 acute acute JJ cord-005646-xhx9pzhj 94 39 physiological physiological JJ cord-005646-xhx9pzhj 94 40 score score NN cord-005646-xhx9pzhj 94 41 component component NN cord-005646-xhx9pzhj 94 42 , , , cord-005646-xhx9pzhj 94 43 the the DT cord-005646-xhx9pzhj 94 44 ROC ROC NNP cord-005646-xhx9pzhj 94 45 can can MD cord-005646-xhx9pzhj 94 46 be be VB cord-005646-xhx9pzhj 94 47 improved improve VBN cord-005646-xhx9pzhj 94 48 to to IN cord-005646-xhx9pzhj 94 49 0.83 0.83 CD cord-005646-xhx9pzhj 94 50 ± ± CD cord-005646-xhx9pzhj 94 51 0.02 0.02 CD cord-005646-xhx9pzhj 94 52 , , , cord-005646-xhx9pzhj 94 53 with with IN cord-005646-xhx9pzhj 94 54 a a DT cord-005646-xhx9pzhj 94 55 good good JJ cord-005646-xhx9pzhj 94 56 fit fit NN cord-005646-xhx9pzhj 94 57 described describe VBN cord-005646-xhx9pzhj 94 58 by by IN cord-005646-xhx9pzhj 94 59 the the DT cord-005646-xhx9pzhj 94 60 goodness goodness NN cord-005646-xhx9pzhj 94 61 - - HYPH cord-005646-xhx9pzhj 94 62 of of IN cord-005646-xhx9pzhj 94 63 - - HYPH cord-005646-xhx9pzhj 94 64 fit fit JJ cord-005646-xhx9pzhj 94 65 test test NN cord-005646-xhx9pzhj 94 66 ( ( -LRB- cord-005646-xhx9pzhj 94 67 CN218 cn218 NN cord-005646-xhx9pzhj 94 68 ] ] -RRB- cord-005646-xhx9pzhj 94 69 = = SYM cord-005646-xhx9pzhj 94 70 3 3 CD cord-005646-xhx9pzhj 94 71 , , , cord-005646-xhx9pzhj 94 72 p p NN cord-005646-xhx9pzhj 94 73 = = SYM cord-005646-xhx9pzhj 94 74 0.89 0.89 CD cord-005646-xhx9pzhj 94 75 ) ) -RRB- cord-005646-xhx9pzhj 94 76 . . . cord-005646-xhx9pzhj 95 1 Discussion Discussion NNP cord-005646-xhx9pzhj 95 2 The the DT cord-005646-xhx9pzhj 95 3 PRISM prism NN cord-005646-xhx9pzhj 95 4 score score NN cord-005646-xhx9pzhj 95 5 is be VBZ cord-005646-xhx9pzhj 95 6 not not RB cord-005646-xhx9pzhj 95 7 accurate accurate JJ cord-005646-xhx9pzhj 95 8 in in IN cord-005646-xhx9pzhj 95 9 our -PRON- PRP$ cord-005646-xhx9pzhj 95 10 patient patient JJ cord-005646-xhx9pzhj 95 11 population population NN cord-005646-xhx9pzhj 95 12 has have VBZ cord-005646-xhx9pzhj 95 13 been be VBN cord-005646-xhx9pzhj 95 14 recalibrated recalibrate VBN cord-005646-xhx9pzhj 95 15 in in IN cord-005646-xhx9pzhj 95 16 view view NN cord-005646-xhx9pzhj 95 17 of of IN cord-005646-xhx9pzhj 95 18 the the DT cord-005646-xhx9pzhj 95 19 poor poor JJ cord-005646-xhx9pzhj 95 20 discriminatory discriminatory JJ cord-005646-xhx9pzhj 95 21 function function NN cord-005646-xhx9pzhj 95 22 that that WDT cord-005646-xhx9pzhj 95 23 we -PRON- PRP cord-005646-xhx9pzhj 95 24 have have VBP cord-005646-xhx9pzhj 95 25 shown show VBN cord-005646-xhx9pzhj 95 26 . . . cord-005646-xhx9pzhj 96 1 Part part NN cord-005646-xhx9pzhj 96 2 of of IN cord-005646-xhx9pzhj 96 3 the the DT cord-005646-xhx9pzhj 96 4 inaccuracy inaccuracy NN cord-005646-xhx9pzhj 96 5 derives derive VBZ cord-005646-xhx9pzhj 96 6 from from IN cord-005646-xhx9pzhj 96 7 the the DT cord-005646-xhx9pzhj 96 8 different different JJ cord-005646-xhx9pzhj 96 9 demographic demographic JJ cord-005646-xhx9pzhj 96 10 characteristics characteristic NNS cord-005646-xhx9pzhj 96 11 of of IN cord-005646-xhx9pzhj 96 12 our -PRON- PRP$ cord-005646-xhx9pzhj 96 13 ICU ICU NNP cord-005646-xhx9pzhj 96 14 population population NN cord-005646-xhx9pzhj 96 15 and and CC cord-005646-xhx9pzhj 96 16 a a DT cord-005646-xhx9pzhj 96 17 different different JJ cord-005646-xhx9pzhj 96 18 pattern pattern NN cord-005646-xhx9pzhj 96 19 of of IN cord-005646-xhx9pzhj 96 20 diseases disease NNS cord-005646-xhx9pzhj 96 21 . . . cord-005646-xhx9pzhj 97 1 In in IN cord-005646-xhx9pzhj 97 2 addition addition NN cord-005646-xhx9pzhj 97 3 to to IN cord-005646-xhx9pzhj 97 4 assessments assessment NNS cord-005646-xhx9pzhj 97 5 of of IN cord-005646-xhx9pzhj 97 6 acute acute JJ cord-005646-xhx9pzhj 97 7 physiological physiological JJ cord-005646-xhx9pzhj 97 8 aberrations aberration NNS cord-005646-xhx9pzhj 97 9 , , , cord-005646-xhx9pzhj 97 10 an an DT cord-005646-xhx9pzhj 97 11 assessment assessment NN cord-005646-xhx9pzhj 97 12 of of IN cord-005646-xhx9pzhj 97 13 nutritional nutritional JJ cord-005646-xhx9pzhj 97 14 status status NN cord-005646-xhx9pzhj 97 15 and and CC cord-005646-xhx9pzhj 97 16 early early JJ cord-005646-xhx9pzhj 97 17 respiratory respiratory JJ cord-005646-xhx9pzhj 97 18 and and CC cord-005646-xhx9pzhj 97 19 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 97 20 failure failure NN cord-005646-xhx9pzhj 97 21 significantly significantly RB cord-005646-xhx9pzhj 97 22 improve improve VBP cord-005646-xhx9pzhj 97 23 the the DT cord-005646-xhx9pzhj 97 24 discriminatory discriminatory JJ cord-005646-xhx9pzhj 97 25 ability ability NN cord-005646-xhx9pzhj 97 26 of of IN cord-005646-xhx9pzhj 97 27 the the DT cord-005646-xhx9pzhj 97 28 PRISM prism NN cord-005646-xhx9pzhj 97 29 score score NN cord-005646-xhx9pzhj 97 30 , , , cord-005646-xhx9pzhj 97 31 These these DT cord-005646-xhx9pzhj 97 32 parameters parameter NNS cord-005646-xhx9pzhj 97 33 have have VBP cord-005646-xhx9pzhj 97 34 been be VBN cord-005646-xhx9pzhj 97 35 devised devise VBN cord-005646-xhx9pzhj 97 36 with with IN cord-005646-xhx9pzhj 97 37 a a DT cord-005646-xhx9pzhj 97 38 view view NN cord-005646-xhx9pzhj 97 39 to to IN cord-005646-xhx9pzhj 97 40 improving improve VBG cord-005646-xhx9pzhj 97 41 the the DT cord-005646-xhx9pzhj 97 42 accuracy accuracy NN cord-005646-xhx9pzhj 97 43 of of IN cord-005646-xhx9pzhj 97 44 PRISM prism NN cord-005646-xhx9pzhj 97 45 in in IN cord-005646-xhx9pzhj 97 46 our -PRON- PRP$ cord-005646-xhx9pzhj 97 47 population population NN cord-005646-xhx9pzhj 97 48 , , , cord-005646-xhx9pzhj 97 49 while while IN cord-005646-xhx9pzhj 97 50 not not RB cord-005646-xhx9pzhj 97 51 decreasing decrease VBG cord-005646-xhx9pzhj 97 52 its -PRON- PRP$ cord-005646-xhx9pzhj 97 53 accuracy accuracy NN cord-005646-xhx9pzhj 97 54 in in IN cord-005646-xhx9pzhj 97 55 ICUs ICUs NNP cord-005646-xhx9pzhj 97 56 similar similar JJ cord-005646-xhx9pzhj 97 57 to to IN cord-005646-xhx9pzhj 97 58 the the DT cord-005646-xhx9pzhj 97 59 reference reference NN cord-005646-xhx9pzhj 97 60 population population NN cord-005646-xhx9pzhj 97 61 . . . cord-005646-xhx9pzhj 98 1 In in IN cord-005646-xhx9pzhj 98 2 interviewing interview VBG cord-005646-xhx9pzhj 98 3 parents parent NNS cord-005646-xhx9pzhj 98 4 regarding regard VBG cord-005646-xhx9pzhj 98 5 how how WRB cord-005646-xhx9pzhj 98 6 physicians physician NNS cord-005646-xhx9pzhj 98 7 have have VBP cord-005646-xhx9pzhj 98 8 communicated communicate VBN cord-005646-xhx9pzhj 98 9 bad bad JJ cord-005646-xhx9pzhj 98 10 news news NN cord-005646-xhx9pzhj 98 11 , , , cord-005646-xhx9pzhj 98 12 the the DT cord-005646-xhx9pzhj 98 13 response response NN cord-005646-xhx9pzhj 98 14 I -PRON- PRP cord-005646-xhx9pzhj 98 15 have have VBP cord-005646-xhx9pzhj 98 16 received receive VBN cord-005646-xhx9pzhj 98 17 is be VBZ cord-005646-xhx9pzhj 98 18 that that IN cord-005646-xhx9pzhj 98 19 it -PRON- PRP cord-005646-xhx9pzhj 98 20 has have VBZ cord-005646-xhx9pzhj 98 21 not not RB cord-005646-xhx9pzhj 98 22 infrequently infrequently RB cord-005646-xhx9pzhj 98 23 been be VBN cord-005646-xhx9pzhj 98 24 done do VBN cord-005646-xhx9pzhj 98 25 without without IN cord-005646-xhx9pzhj 98 26 appropriate appropriate JJ cord-005646-xhx9pzhj 98 27 care care NN cord-005646-xhx9pzhj 98 28 , , , cord-005646-xhx9pzhj 98 29 understanding understanding NN cord-005646-xhx9pzhj 98 30 and and CC cord-005646-xhx9pzhj 98 31 compassion compassion NN cord-005646-xhx9pzhj 98 32 . . . cord-005646-xhx9pzhj 99 1 Personal personal JJ cord-005646-xhx9pzhj 99 2 experience experience NN cord-005646-xhx9pzhj 99 3 and and CC cord-005646-xhx9pzhj 99 4 the the DT cord-005646-xhx9pzhj 99 5 lessons lesson NNS cord-005646-xhx9pzhj 99 6 learned learn VBN cord-005646-xhx9pzhj 99 7 from from IN cord-005646-xhx9pzhj 99 8 parents parent NNS cord-005646-xhx9pzhj 99 9 , , , cord-005646-xhx9pzhj 99 10 chaplains chaplain NNS cord-005646-xhx9pzhj 99 11 and and CC cord-005646-xhx9pzhj 99 12 others other NNS cord-005646-xhx9pzhj 99 13 who who WP cord-005646-xhx9pzhj 99 14 deal deal VBP cord-005646-xhx9pzhj 99 15 extensively extensively RB cord-005646-xhx9pzhj 99 16 with with IN cord-005646-xhx9pzhj 99 17 these these DT cord-005646-xhx9pzhj 99 18 situations situation NNS cord-005646-xhx9pzhj 99 19 have have VBP cord-005646-xhx9pzhj 99 20 provided provide VBN cord-005646-xhx9pzhj 99 21 me -PRON- PRP cord-005646-xhx9pzhj 99 22 with with IN cord-005646-xhx9pzhj 99 23 an an DT cord-005646-xhx9pzhj 99 24 approach approach NN cord-005646-xhx9pzhj 99 25 that that WDT cord-005646-xhx9pzhj 99 26 has have VBZ cord-005646-xhx9pzhj 99 27 been be VBN cord-005646-xhx9pzhj 99 28 supportive supportive JJ cord-005646-xhx9pzhj 99 29 , , , cord-005646-xhx9pzhj 99 30 compassionate compassionate JJ cord-005646-xhx9pzhj 99 31 , , , cord-005646-xhx9pzhj 99 32 and and CC cord-005646-xhx9pzhj 99 33 caring care VBG cord-005646-xhx9pzhj 99 34 . . . cord-005646-xhx9pzhj 100 1 An an DT cord-005646-xhx9pzhj 100 2 especially especially RB cord-005646-xhx9pzhj 100 3 difficult difficult JJ cord-005646-xhx9pzhj 100 4 communication communication NN cord-005646-xhx9pzhj 100 5 situation situation NN cord-005646-xhx9pzhj 100 6 for for IN cord-005646-xhx9pzhj 100 7 the the DT cord-005646-xhx9pzhj 100 8 intensivist intensivist NN cord-005646-xhx9pzhj 100 9 occurs occur VBZ cord-005646-xhx9pzhj 100 10 when when WRB cord-005646-xhx9pzhj 100 11 the the DT cord-005646-xhx9pzhj 100 12 parents parent NNS cord-005646-xhx9pzhj 100 13 have have VBP cord-005646-xhx9pzhj 100 14 to to TO cord-005646-xhx9pzhj 100 15 be be VB cord-005646-xhx9pzhj 100 16 informed inform VBN cord-005646-xhx9pzhj 100 17 of of IN cord-005646-xhx9pzhj 100 18 the the DT cord-005646-xhx9pzhj 100 19 death death NN cord-005646-xhx9pzhj 100 20 of of IN cord-005646-xhx9pzhj 100 21 their -PRON- PRP$ cord-005646-xhx9pzhj 100 22 child child NN cord-005646-xhx9pzhj 100 23 . . . cord-005646-xhx9pzhj 101 1 For for IN cord-005646-xhx9pzhj 101 2 the the DT cord-005646-xhx9pzhj 101 3 parent parent NN cord-005646-xhx9pzhj 101 4 , , , cord-005646-xhx9pzhj 101 5 death death NN cord-005646-xhx9pzhj 101 6 is be VBZ cord-005646-xhx9pzhj 101 7 the the DT cord-005646-xhx9pzhj 101 8 hardest hard JJS cord-005646-xhx9pzhj 101 9 loss loss NN cord-005646-xhx9pzhj 101 10 of of IN cord-005646-xhx9pzhj 101 11 all all DT cord-005646-xhx9pzhj 101 12 -the -the DT cord-005646-xhx9pzhj 101 13 ultimate ultimate JJ cord-005646-xhx9pzhj 101 14 unalterable unalterable JJ cord-005646-xhx9pzhj 101 15 loss loss NN cord-005646-xhx9pzhj 101 16 . . . cord-005646-xhx9pzhj 102 1 Circumstances circumstance NNS cord-005646-xhx9pzhj 102 2 surrounding surround VBG cord-005646-xhx9pzhj 102 3 the the DT cord-005646-xhx9pzhj 102 4 death death NN cord-005646-xhx9pzhj 102 5 are be VBP cord-005646-xhx9pzhj 102 6 an an DT cord-005646-xhx9pzhj 102 7 important important JJ cord-005646-xhx9pzhj 102 8 consideration consideration NN cord-005646-xhx9pzhj 102 9 ( ( -LRB- cord-005646-xhx9pzhj 102 10 e.g. e.g. RB cord-005646-xhx9pzhj 102 11 , , , cord-005646-xhx9pzhj 102 12 a a DT cord-005646-xhx9pzhj 102 13 fatal fatal JJ cord-005646-xhx9pzhj 102 14 crash crash NN cord-005646-xhx9pzhj 102 15 caused cause VBN cord-005646-xhx9pzhj 102 16 by by IN cord-005646-xhx9pzhj 102 17 a a DT cord-005646-xhx9pzhj 102 18 drunken drunken JJ cord-005646-xhx9pzhj 102 19 driver driver NN cord-005646-xhx9pzhj 102 20 , , , cord-005646-xhx9pzhj 102 21 a a DT cord-005646-xhx9pzhj 102 22 prolonged prolonged JJ cord-005646-xhx9pzhj 102 23 illness illness NN cord-005646-xhx9pzhj 102 24 , , , cord-005646-xhx9pzhj 102 25 a a DT cord-005646-xhx9pzhj 102 26 suicide suicide NN cord-005646-xhx9pzhj 102 27 , , , cord-005646-xhx9pzhj 102 28 AIDS AIDS NNP cord-005646-xhx9pzhj 102 29 ) ) -RRB- cord-005646-xhx9pzhj 102 30 . . . cord-005646-xhx9pzhj 103 1 Each each DT cord-005646-xhx9pzhj 103 2 produces produce VBZ cord-005646-xhx9pzhj 103 3 a a DT cord-005646-xhx9pzhj 103 4 different different JJ cord-005646-xhx9pzhj 103 5 grief grief NN cord-005646-xhx9pzhj 103 6 reaction reaction NN cord-005646-xhx9pzhj 103 7 . . . cord-005646-xhx9pzhj 104 1 The the DT cord-005646-xhx9pzhj 104 2 physician physician NN cord-005646-xhx9pzhj 104 3 needs need VBZ cord-005646-xhx9pzhj 104 4 to to TO cord-005646-xhx9pzhj 104 5 inform inform VB cord-005646-xhx9pzhj 104 6 parents parent NNS cord-005646-xhx9pzhj 104 7 of of IN cord-005646-xhx9pzhj 104 8 their -PRON- PRP$ cord-005646-xhx9pzhj 104 9 child child NN cord-005646-xhx9pzhj 104 10 's 's POS cord-005646-xhx9pzhj 104 11 death death NN cord-005646-xhx9pzhj 104 12 sympathetically sympathetically RB cord-005646-xhx9pzhj 104 13 coming come VBG cord-005646-xhx9pzhj 104 14 right right RB cord-005646-xhx9pzhj 104 15 out out RB cord-005646-xhx9pzhj 104 16 with with IN cord-005646-xhx9pzhj 104 17 the the DT cord-005646-xhx9pzhj 104 18 news news NN cord-005646-xhx9pzhj 104 19 and and CC cord-005646-xhx9pzhj 104 20 leaving leave VBG cord-005646-xhx9pzhj 104 21 details detail NNS cord-005646-xhx9pzhj 104 22 until until IN cord-005646-xhx9pzhj 104 23 later later RB cord-005646-xhx9pzhj 104 24 . . . cord-005646-xhx9pzhj 105 1 Allow allow VB cord-005646-xhx9pzhj 105 2 pauses pause NNS cord-005646-xhx9pzhj 105 3 and and CC cord-005646-xhx9pzhj 105 4 time time NN cord-005646-xhx9pzhj 105 5 for for IN cord-005646-xhx9pzhj 105 6 the the DT cord-005646-xhx9pzhj 105 7 paren~ paren~ NNP cord-005646-xhx9pzhj 105 8 to to TO cord-005646-xhx9pzhj 105 9 express express VB cord-005646-xhx9pzhj 105 10 sorrow sorrow NN cord-005646-xhx9pzhj 105 11 and and CC cord-005646-xhx9pzhj 105 12 grief grief NN cord-005646-xhx9pzhj 105 13 , , , cord-005646-xhx9pzhj 105 14 The the DT cord-005646-xhx9pzhj 105 15 best good JJS cord-005646-xhx9pzhj 105 16 communication communication NN cord-005646-xhx9pzhj 105 17 may may MD cord-005646-xhx9pzhj 105 18 be be VB cord-005646-xhx9pzhj 105 19 thoughtful thoughtful JJ cord-005646-xhx9pzhj 105 20 silence silence NN cord-005646-xhx9pzhj 105 21 and and CC cord-005646-xhx9pzhj 105 22 a a DT cord-005646-xhx9pzhj 105 23 tender tender JJ cord-005646-xhx9pzhj 105 24 touch touch NN cord-005646-xhx9pzhj 105 25 . . . cord-005646-xhx9pzhj 106 1 There there EX cord-005646-xhx9pzhj 106 2 is be VBZ cord-005646-xhx9pzhj 106 3 disbelief disbelief NN cord-005646-xhx9pzhj 106 4 that that IN cord-005646-xhx9pzhj 106 5 this this DT cord-005646-xhx9pzhj 106 6 happened happen VBD cord-005646-xhx9pzhj 106 7 . . . cord-005646-xhx9pzhj 107 1 It -PRON- PRP cord-005646-xhx9pzhj 107 2 is be VBZ cord-005646-xhx9pzhj 107 3 necessary necessary JJ cord-005646-xhx9pzhj 107 4 to to TO cord-005646-xhx9pzhj 107 5 repeat repeat VB cord-005646-xhx9pzhj 107 6 oneself oneself PRP cord-005646-xhx9pzhj 107 7 . . . cord-005646-xhx9pzhj 108 1 Acknowledgment acknowledgment NN cord-005646-xhx9pzhj 108 2 of of IN cord-005646-xhx9pzhj 108 3 the the DT cord-005646-xhx9pzhj 108 4 parent parent NN cord-005646-xhx9pzhj 108 5 's 's POS cord-005646-xhx9pzhj 108 6 " " `` cord-005646-xhx9pzhj 108 7 feeling feel VBG cord-005646-xhx9pzhj 108 8 terrible terrible JJ cord-005646-xhx9pzhj 108 9 " " '' cord-005646-xhx9pzhj 108 10 and and CC cord-005646-xhx9pzhj 108 11 the the DT cord-005646-xhx9pzhj 108 12 physician physician NN cord-005646-xhx9pzhj 108 13 's 's POS cord-005646-xhx9pzhj 108 14 acknowledgment acknowledgment NN cord-005646-xhx9pzhj 108 15 of of IN cord-005646-xhx9pzhj 108 16 how how WRB cord-005646-xhx9pzhj 108 17 terrible terrible JJ cord-005646-xhx9pzhj 108 18 he -PRON- PRP cord-005646-xhx9pzhj 109 1 /she /she : cord-005646-xhx9pzhj 109 2 feels feel VBZ cord-005646-xhx9pzhj 109 3 that that IN cord-005646-xhx9pzhj 109 4 the the DT cord-005646-xhx9pzhj 109 5 life life NN cord-005646-xhx9pzhj 109 6 of of IN cord-005646-xhx9pzhj 109 7 the the DT cord-005646-xhx9pzhj 109 8 child child NN cord-005646-xhx9pzhj 109 9 could could MD cord-005646-xhx9pzhj 109 10 not not RB cord-005646-xhx9pzhj 109 11 be be VB cord-005646-xhx9pzhj 109 12 saved save VBN cord-005646-xhx9pzhj 110 1 is be VBZ cord-005646-xhx9pzhj 110 2 an an DT cord-005646-xhx9pzhj 110 3 important important JJ cord-005646-xhx9pzhj 110 4 first first JJ cord-005646-xhx9pzhj 110 5 step step NN cord-005646-xhx9pzhj 110 6 in in IN cord-005646-xhx9pzhj 110 7 the the DT cord-005646-xhx9pzhj 110 8 parent parent NN cord-005646-xhx9pzhj 110 9 's 's POS cord-005646-xhx9pzhj 110 10 dealing deal VBG cord-005646-xhx9pzhj 110 11 with with IN cord-005646-xhx9pzhj 110 12 this this DT cord-005646-xhx9pzhj 110 13 tragic tragic JJ cord-005646-xhx9pzhj 110 14 loss loss NN cord-005646-xhx9pzhj 110 15 . . . cord-005646-xhx9pzhj 111 1 With with IN cord-005646-xhx9pzhj 111 2 prolonged prolonged JJ cord-005646-xhx9pzhj 111 3 resuscitation resuscitation NN cord-005646-xhx9pzhj 111 4 , , , cord-005646-xhx9pzhj 111 5 it -PRON- PRP cord-005646-xhx9pzhj 111 6 is be VBZ cord-005646-xhx9pzhj 111 7 helpful helpful JJ cord-005646-xhx9pzhj 111 8 to to TO cord-005646-xhx9pzhj 111 9 have have VB cord-005646-xhx9pzhj 111 10 a a DT cord-005646-xhx9pzhj 111 11 member member NN cord-005646-xhx9pzhj 111 12 of of IN cord-005646-xhx9pzhj 111 13 the the DT cord-005646-xhx9pzhj 111 14 ICU ICU NNP cord-005646-xhx9pzhj 111 15 team team NN cord-005646-xhx9pzhj 111 16 talk talk VBP cord-005646-xhx9pzhj 111 17 to to IN cord-005646-xhx9pzhj 111 18 the the DT cord-005646-xhx9pzhj 111 19 parents parent NNS cord-005646-xhx9pzhj 111 20 while while IN cord-005646-xhx9pzhj 111 21 the the DT cord-005646-xhx9pzhj 111 22 resuscitative resuscitative JJ cord-005646-xhx9pzhj 111 23 efforts effort NNS cord-005646-xhx9pzhj 111 24 are be VBP cord-005646-xhx9pzhj 111 25 ongoing ongoing JJ cord-005646-xhx9pzhj 111 26 so so IN cord-005646-xhx9pzhj 111 27 that that IN cord-005646-xhx9pzhj 111 28 the the DT cord-005646-xhx9pzhj 111 29 parents parent NNS cord-005646-xhx9pzhj 111 30 are be VBP cord-005646-xhx9pzhj 111 31 not not RB cord-005646-xhx9pzhj 111 32 left leave VBN cord-005646-xhx9pzhj 111 33 unsupported unsupported JJ cord-005646-xhx9pzhj 111 34 at at IN cord-005646-xhx9pzhj 111 35 this this DT cord-005646-xhx9pzhj 111 36 time time NN cord-005646-xhx9pzhj 111 37 . . . cord-005646-xhx9pzhj 112 1 A a DT cord-005646-xhx9pzhj 112 2 progress progress NN cord-005646-xhx9pzhj 112 3 report report NN cord-005646-xhx9pzhj 112 4 should should MD cord-005646-xhx9pzhj 112 5 be be VB cord-005646-xhx9pzhj 112 6 delivered deliver VBN cord-005646-xhx9pzhj 112 7 in in IN cord-005646-xhx9pzhj 112 8 a a DT cord-005646-xhx9pzhj 112 9 caring caring JJ cord-005646-xhx9pzhj 112 10 , , , cord-005646-xhx9pzhj 112 11 lucid lucid JJ cord-005646-xhx9pzhj 112 12 , , , cord-005646-xhx9pzhj 112 13 and and CC cord-005646-xhx9pzhj 112 14 sensitive.manner sensitive.manner NNS cord-005646-xhx9pzhj 112 15 , , , cord-005646-xhx9pzhj 112 16 indicating indicate VBG cord-005646-xhx9pzhj 112 17 that that IN cord-005646-xhx9pzhj 112 18 every every DT cord-005646-xhx9pzhj 112 19 effort effort NN cord-005646-xhx9pzhj 112 20 is be VBZ cord-005646-xhx9pzhj 112 21 being be VBG cord-005646-xhx9pzhj 112 22 made make VBN cord-005646-xhx9pzhj 112 23 to to TO cord-005646-xhx9pzhj 112 24 save save VB cord-005646-xhx9pzhj 112 25 the the DT cord-005646-xhx9pzhj 112 26 life life NN cord-005646-xhx9pzhj 112 27 of of IN cord-005646-xhx9pzhj 112 28 their -PRON- PRP$ cord-005646-xhx9pzhj 112 29 desperately desperately RB cord-005646-xhx9pzhj 112 30 injured injure VBN cord-005646-xhx9pzhj 112 31 child child NN cord-005646-xhx9pzhj 112 32 . . . cord-005646-xhx9pzhj 113 1 After after IN cord-005646-xhx9pzhj 113 2 a a DT cord-005646-xhx9pzhj 113 3 child child NN cord-005646-xhx9pzhj 113 4 has have VBZ cord-005646-xhx9pzhj 113 5 died die VBN cord-005646-xhx9pzhj 113 6 , , , cord-005646-xhx9pzhj 113 7 it -PRON- PRP cord-005646-xhx9pzhj 113 8 is be VBZ cord-005646-xhx9pzhj 113 9 helpful helpful JJ cord-005646-xhx9pzhj 113 10 to to IN cord-005646-xhx9pzhj 113 11 the the DT cord-005646-xhx9pzhj 113 12 family family NN cord-005646-xhx9pzhj 113 13 if if IN cord-005646-xhx9pzhj 113 14 the the DT cord-005646-xhx9pzhj 113 15 physician physician NN cord-005646-xhx9pzhj 113 16 maintains maintain VBZ cord-005646-xhx9pzhj 113 17 some some DT cord-005646-xhx9pzhj 113 18 contact contact NN cord-005646-xhx9pzhj 113 19 with with IN cord-005646-xhx9pzhj 113 20 them -PRON- PRP cord-005646-xhx9pzhj 113 21 . . . cord-005646-xhx9pzhj 114 1 This this DT cord-005646-xhx9pzhj 114 2 should should MD cord-005646-xhx9pzhj 114 3 take take VB cord-005646-xhx9pzhj 114 4 the the DT cord-005646-xhx9pzhj 114 5 form form NN cord-005646-xhx9pzhj 114 6 of of IN cord-005646-xhx9pzhj 114 7 follow follow VB cord-005646-xhx9pzhj 114 8 - - HYPH cord-005646-xhx9pzhj 114 9 up up RP cord-005646-xhx9pzhj 114 10 telephone telephone NN cord-005646-xhx9pzhj 114 11 calls call NNS cord-005646-xhx9pzhj 114 12 at at IN cord-005646-xhx9pzhj 114 13 approximately approximately RB cord-005646-xhx9pzhj 114 14 6 6 CD cord-005646-xhx9pzhj 114 15 , , , cord-005646-xhx9pzhj 114 16 12 12 CD cord-005646-xhx9pzhj 114 17 , , , cord-005646-xhx9pzhj 114 18 and and CC cord-005646-xhx9pzhj 114 19 24 24 CD cord-005646-xhx9pzhj 114 20 months month NNS cord-005646-xhx9pzhj 114 21 . . . cord-005646-xhx9pzhj 115 1 This this DT cord-005646-xhx9pzhj 115 2 can can MD cord-005646-xhx9pzhj 115 3 help help VB cord-005646-xhx9pzhj 115 4 to to TO cord-005646-xhx9pzhj 115 5 screen screen VB cord-005646-xhx9pzhj 115 6 for for IN cord-005646-xhx9pzhj 115 7 depression depression NN cord-005646-xhx9pzhj 115 8 in in IN cord-005646-xhx9pzhj 115 9 the the DT cord-005646-xhx9pzhj 115 10 parents parent NNS cord-005646-xhx9pzhj 115 11 . . . cord-005646-xhx9pzhj 116 1 In in IN cord-005646-xhx9pzhj 116 2 giving give VBG cord-005646-xhx9pzhj 116 3 bad bad JJ cord-005646-xhx9pzhj 116 4 news news NN cord-005646-xhx9pzhj 116 5 to to IN cord-005646-xhx9pzhj 116 6 the the DT cord-005646-xhx9pzhj 116 7 family family NN cord-005646-xhx9pzhj 116 8 and and CC cord-005646-xhx9pzhj 116 9 making make VBG cord-005646-xhx9pzhj 116 10 every every DT cord-005646-xhx9pzhj 116 11 effort effort NN cord-005646-xhx9pzhj 116 12 to to TO cord-005646-xhx9pzhj 116 13 support support VB cord-005646-xhx9pzhj 116 14 them -PRON- PRP cord-005646-xhx9pzhj 116 15 through through IN cord-005646-xhx9pzhj 116 16 this this DT cord-005646-xhx9pzhj 116 17 tragic tragic JJ cord-005646-xhx9pzhj 116 18 time time NN cord-005646-xhx9pzhj 116 19 , , , cord-005646-xhx9pzhj 116 20 it -PRON- PRP cord-005646-xhx9pzhj 116 21 is be VBZ cord-005646-xhx9pzhj 116 22 necessary necessary JJ cord-005646-xhx9pzhj 116 23 to to TO cord-005646-xhx9pzhj 116 24 remind remind VB cord-005646-xhx9pzhj 116 25 oneself oneself PRP cord-005646-xhx9pzhj 116 26 that that IN cord-005646-xhx9pzhj 116 27 the the DT cord-005646-xhx9pzhj 116 28 intensivist intensivist NN cord-005646-xhx9pzhj 116 29 has have VBZ cord-005646-xhx9pzhj 116 30 personal personal JJ cord-005646-xhx9pzhj 116 31 needs need NNS cord-005646-xhx9pzhj 116 32 for for IN cord-005646-xhx9pzhj 116 33 dealing deal VBG cord-005646-xhx9pzhj 116 34 with with IN cord-005646-xhx9pzhj 116 35 grief grief NN cord-005646-xhx9pzhj 116 36 and and CC cord-005646-xhx9pzhj 116 37 will will MD cord-005646-xhx9pzhj 116 38 also also RB cord-005646-xhx9pzhj 116 39 require require VB cord-005646-xhx9pzhj 116 40 support support NN cord-005646-xhx9pzhj 116 41 to to TO cord-005646-xhx9pzhj 116 42 pass pass VB cord-005646-xhx9pzhj 116 43 through through IN cord-005646-xhx9pzhj 116 44 this this DT cord-005646-xhx9pzhj 116 45 stage stage NN cord-005646-xhx9pzhj 116 46 . . . cord-005646-xhx9pzhj 117 1 Direct direct JJ cord-005646-xhx9pzhj 117 2 evidence evidence NN cord-005646-xhx9pzhj 117 3 that that IN cord-005646-xhx9pzhj 117 4 child child NN cord-005646-xhx9pzhj 117 5 mortality mortality NN cord-005646-xhx9pzhj 117 6 is be VBZ cord-005646-xhx9pzhj 117 7 lower low JJR cord-005646-xhx9pzhj 117 8 in in IN cord-005646-xhx9pzhj 117 9 specialist specialist JJ cord-005646-xhx9pzhj 117 10 pediatric pediatric JJ cord-005646-xhx9pzhj 117 11 ICUs icus NN cord-005646-xhx9pzhj 117 12 comes come VBZ cord-005646-xhx9pzhj 117 13 from from IN cord-005646-xhx9pzhj 117 14 3 3 CD cord-005646-xhx9pzhj 117 15 studies study NNS cord-005646-xhx9pzhj 117 16 . . . cord-005646-xhx9pzhj 118 1 A a DT cord-005646-xhx9pzhj 118 2 study study NN cord-005646-xhx9pzhj 118 3 in in IN cord-005646-xhx9pzhj 118 4 Oregon Oregon NNP cord-005646-xhx9pzhj 118 5 ( ( -LRB- cord-005646-xhx9pzhj 118 6 CCM CCM NNP cord-005646-xhx9pzhj 118 7 1981 1981 CD cord-005646-xhx9pzhj 118 8 ; ; : cord-005646-xhx9pzhj 118 9 19:150 19:150 CD cord-005646-xhx9pzhj 118 10 - - SYM cord-005646-xhx9pzhj 118 11 9 9 CD cord-005646-xhx9pzhj 118 12 ) ) -RRB- cord-005646-xhx9pzhj 118 13 found find VBD cord-005646-xhx9pzhj 118 14 that that IN cord-005646-xhx9pzhj 118 15 mortality mortality NN cord-005646-xhx9pzhj 118 16 adjusted adjust VBN cord-005646-xhx9pzhj 118 17 for for IN cord-005646-xhx9pzhj 118 18 severity severity NN cord-005646-xhx9pzhj 118 19 of of IN cord-005646-xhx9pzhj 118 20 illness illness NN cord-005646-xhx9pzhj 118 21 was be VBD cord-005646-xhx9pzhj 118 22 102 102 CD cord-005646-xhx9pzhj 118 23 % % NN cord-005646-xhx9pzhj 118 24 of of IN cord-005646-xhx9pzhj 118 25 expected expect VBN cord-005646-xhx9pzhj 118 26 in in IN cord-005646-xhx9pzhj 118 27 3 3 CD cord-005646-xhx9pzhj 118 28 pediatric pediatric JJ cord-005646-xhx9pzhj 118 29 units unit NNS cord-005646-xhx9pzhj 118 30 and and CC cord-005646-xhx9pzhj 118 31 139 139 CD cord-005646-xhx9pzhj 118 32 % % NN cord-005646-xhx9pzhj 118 33 of of IN cord-005646-xhx9pzhj 118 34 expected expect VBN cord-005646-xhx9pzhj 118 35 in in IN cord-005646-xhx9pzhj 118 36 71 71 CD cord-005646-xhx9pzhj 118 37 general general JJ cord-005646-xhx9pzhj 118 38 units unit NNS cord-005646-xhx9pzhj 118 39 ( ( -LRB- cord-005646-xhx9pzhj 118 40 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 118 41 ) ) -RRB- cord-005646-xhx9pzhj 118 42 . . . cord-005646-xhx9pzhj 119 1 A a DT cord-005646-xhx9pzhj 119 2 study study NN cord-005646-xhx9pzhj 119 3 in in IN cord-005646-xhx9pzhj 119 4 Holland Holland NNP cord-005646-xhx9pzhj 119 5 ( ( -LRB- cord-005646-xhx9pzhj 119 6 CCM CCM NNP cord-005646-xhx9pzhj 119 7 1995 1995 CD cord-005646-xhx9pzhj 119 8 ; ; : cord-005646-xhx9pzhj 119 9 23:238 23:238 CD cord-005646-xhx9pzhj 119 10 - - SYM cord-005646-xhx9pzhj 119 11 45 45 CD cord-005646-xhx9pzhj 119 12 ) ) -RRB- cord-005646-xhx9pzhj 119 13 found find VBD cord-005646-xhx9pzhj 119 14 that that IN cord-005646-xhx9pzhj 119 15 mortality mortality NN cord-005646-xhx9pzhj 119 16 in in IN cord-005646-xhx9pzhj 119 17 high high JJ cord-005646-xhx9pzhj 119 18 risk risk NN cord-005646-xhx9pzhj 119 19 patients patient NNS cord-005646-xhx9pzhj 119 20 was be VBD cord-005646-xhx9pzhj 119 21 85 85 CD cord-005646-xhx9pzhj 119 22 % % NN cord-005646-xhx9pzhj 119 23 of of IN cord-005646-xhx9pzhj 119 24 expected expect VBN cord-005646-xhx9pzhj 119 25 in in IN cord-005646-xhx9pzhj 119 26 6 6 CD cord-005646-xhx9pzhj 119 27 tertiary tertiary JJ cord-005646-xhx9pzhj 119 28 pediatric pediatric JJ cord-005646-xhx9pzhj 119 29 units unit NNS cord-005646-xhx9pzhj 119 30 , , , cord-005646-xhx9pzhj 119 31 and and CC cord-005646-xhx9pzhj 119 32 143 143 CD cord-005646-xhx9pzhj 119 33 % % NN cord-005646-xhx9pzhj 119 34 of of IN cord-005646-xhx9pzhj 119 35 expected expect VBN cord-005646-xhx9pzhj 119 36 in in IN cord-005646-xhx9pzhj 119 37 4 4 CD cord-005646-xhx9pzhj 119 38 nontertiary nontertiary JJ cord-005646-xhx9pzhj 119 39 units unit NNS cord-005646-xhx9pzhj 119 40 ( ( -LRB- cord-005646-xhx9pzhj 119 41 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 119 42 ) ) -RRB- cord-005646-xhx9pzhj 119 43 . . . cord-005646-xhx9pzhj 120 1 A a DT cord-005646-xhx9pzhj 120 2 third third JJ cord-005646-xhx9pzhj 120 3 unpublished unpublished JJ cord-005646-xhx9pzhj 120 4 study study NN cord-005646-xhx9pzhj 120 5 , , , cord-005646-xhx9pzhj 120 6 has have VBZ cord-005646-xhx9pzhj 120 7 found find VBN cord-005646-xhx9pzhj 120 8 that that IN cord-005646-xhx9pzhj 120 9 children child NNS cord-005646-xhx9pzhj 120 10 in in IN cord-005646-xhx9pzhj 120 11 Victoria Victoria NNP cord-005646-xhx9pzhj 120 12 ( ( -LRB- cord-005646-xhx9pzhj 120 13 who who WP cord-005646-xhx9pzhj 120 14 almost almost RB cord-005646-xhx9pzhj 120 15 all all DT cord-005646-xhx9pzhj 120 16 receive receive VBP cord-005646-xhx9pzhj 120 17 intensive intensive JJ cord-005646-xhx9pzhj 120 18 care care NN cord-005646-xhx9pzhj 120 19 in in IN cord-005646-xhx9pzhj 120 20 a a DT cord-005646-xhx9pzhj 120 21 pediatric pediatric JJ cord-005646-xhx9pzhj 120 22 ICU ICU NNP cord-005646-xhx9pzhj 120 23 ) ) -RRB- cord-005646-xhx9pzhj 120 24 have have VBP cord-005646-xhx9pzhj 120 25 a a DT cord-005646-xhx9pzhj 120 26 much much RB cord-005646-xhx9pzhj 120 27 lower low JJR cord-005646-xhx9pzhj 120 28 standardised standardised JJ cord-005646-xhx9pzhj 120 29 mortality mortality NN cord-005646-xhx9pzhj 120 30 rate rate NN cord-005646-xhx9pzhj 120 31 than than IN cord-005646-xhx9pzhj 120 32 children child NNS cord-005646-xhx9pzhj 120 33 in in IN cord-005646-xhx9pzhj 120 34 the the DT cord-005646-xhx9pzhj 120 35 Trent Trent NNP cord-005646-xhx9pzhj 120 36 region region NN cord-005646-xhx9pzhj 120 37 of of IN cord-005646-xhx9pzhj 120 38 the the DT cord-005646-xhx9pzhj 120 39 UK UK NNP cord-005646-xhx9pzhj 120 40 ( ( -LRB- cord-005646-xhx9pzhj 120 41 where where WRB cord-005646-xhx9pzhj 120 42 many many JJ cord-005646-xhx9pzhj 120 43 children child NNS cord-005646-xhx9pzhj 120 44 receive receive VBP cord-005646-xhx9pzhj 120 45 intensive intensive JJ cord-005646-xhx9pzhj 120 46 care care NN cord-005646-xhx9pzhj 120 47 in in IN cord-005646-xhx9pzhj 120 48 adult adult NN cord-005646-xhx9pzhj 120 49 ICUs ICUs NNP cord-005646-xhx9pzhj 120 50 ) ) -RRB- cord-005646-xhx9pzhj 120 51 . . . cord-005646-xhx9pzhj 121 1 There there EX cord-005646-xhx9pzhj 121 2 is be VBZ cord-005646-xhx9pzhj 121 3 indirect indirect JJ cord-005646-xhx9pzhj 121 4 evidence evidence NN cord-005646-xhx9pzhj 121 5 that that IN cord-005646-xhx9pzhj 121 6 ICUs ICUs NNP cord-005646-xhx9pzhj 121 7 looking look VBG cord-005646-xhx9pzhj 121 8 after after IN cord-005646-xhx9pzhj 121 9 many many JJ cord-005646-xhx9pzhj 121 10 children child NNS cord-005646-xhx9pzhj 121 11 are be VBP cord-005646-xhx9pzhj 121 12 likely likely JJ cord-005646-xhx9pzhj 121 13 , , , cord-005646-xhx9pzhj 121 14 on on IN cord-005646-xhx9pzhj 121 15 average average JJ cord-005646-xhx9pzhj 121 16 , , , cord-005646-xhx9pzhj 121 17 to to TO cord-005646-xhx9pzhj 121 18 perform perform VB cord-005646-xhx9pzhj 121 19 better well JJR cord-005646-xhx9pzhj 121 20 than than IN cord-005646-xhx9pzhj 121 21 ICUs ICUs NNP cord-005646-xhx9pzhj 121 22 looking look VBG cord-005646-xhx9pzhj 121 23 after after IN cord-005646-xhx9pzhj 121 24 few few JJ cord-005646-xhx9pzhj 121 25 children child NNS cord-005646-xhx9pzhj 121 26 : : : cord-005646-xhx9pzhj 121 27 numerous numerous JJ cord-005646-xhx9pzhj 121 28 studies study NNS cord-005646-xhx9pzhj 121 29 in in IN cord-005646-xhx9pzhj 121 30 many many JJ cord-005646-xhx9pzhj 121 31 specialities speciality NNS cord-005646-xhx9pzhj 121 32 have have VBP cord-005646-xhx9pzhj 121 33 found find VBN cord-005646-xhx9pzhj 121 34 that that IN cord-005646-xhx9pzhj 121 35 units unit NNS cord-005646-xhx9pzhj 121 36 looking look VBG cord-005646-xhx9pzhj 121 37 after after IN cord-005646-xhx9pzhj 121 38 many many JJ cord-005646-xhx9pzhj 121 39 cases case NNS cord-005646-xhx9pzhj 121 40 of of IN cord-005646-xhx9pzhj 121 41 a a DT cord-005646-xhx9pzhj 121 42 particular particular JJ cord-005646-xhx9pzhj 121 43 disease disease NN cord-005646-xhx9pzhj 121 44 have have VBP cord-005646-xhx9pzhj 121 45 better well JJR cord-005646-xhx9pzhj 121 46 results result NNS cord-005646-xhx9pzhj 121 47 than than IN cord-005646-xhx9pzhj 121 48 units unit NNS cord-005646-xhx9pzhj 121 49 with with IN cord-005646-xhx9pzhj 121 50 few few JJ cord-005646-xhx9pzhj 121 51 cases case NNS cord-005646-xhx9pzhj 121 52 . . . cord-005646-xhx9pzhj 122 1 See see VB cord-005646-xhx9pzhj 122 2 Luft Luft NNP cord-005646-xhx9pzhj 122 3 HS HS NNP cord-005646-xhx9pzhj 122 4 , , , cord-005646-xhx9pzhj 122 5 " " `` cord-005646-xhx9pzhj 122 6 Hospital Hospital NNP cord-005646-xhx9pzhj 122 7 Volume Volume NNP cord-005646-xhx9pzhj 122 8 , , , cord-005646-xhx9pzhj 122 9 Physician Physician NNP cord-005646-xhx9pzhj 122 10 Volume Volume NNP cord-005646-xhx9pzhj 122 11 , , , cord-005646-xhx9pzhj 122 12 and and CC cord-005646-xhx9pzhj 122 13 Patient Patient NNP cord-005646-xhx9pzhj 122 14 Outcomes Outcomes NNPS cord-005646-xhx9pzhj 122 15 " " '' cord-005646-xhx9pzhj 122 16 , , , cord-005646-xhx9pzhj 122 17 HAPP HAPP NNP cord-005646-xhx9pzhj 122 18 , , , cord-005646-xhx9pzhj 122 19 1990 1990 CD cord-005646-xhx9pzhj 122 20 ; ; : cord-005646-xhx9pzhj 122 21 and and CC cord-005646-xhx9pzhj 122 22 Farley Farley NNP cord-005646-xhx9pzhj 122 23 D D NNP cord-005646-xhx9pzhj 122 24 , , , cord-005646-xhx9pzhj 122 25 Medical Medical NNP cord-005646-xhx9pzhj 122 26 Care Care NNP cord-005646-xhx9pzhj 122 27 1992 1992 CD cord-005646-xhx9pzhj 122 28 ; ; : cord-005646-xhx9pzhj 122 29 30:77 30:77 CD cord-005646-xhx9pzhj 122 30 - - SYM cord-005646-xhx9pzhj 122 31 94 94 CD cord-005646-xhx9pzhj 122 32 . . . cord-005646-xhx9pzhj 123 1 Compared compare VBN cord-005646-xhx9pzhj 123 2 to to IN cord-005646-xhx9pzhj 123 3 general general JJ cord-005646-xhx9pzhj 123 4 ICUs ICUs NNP cord-005646-xhx9pzhj 123 5 , , , cord-005646-xhx9pzhj 123 6 medical medical JJ cord-005646-xhx9pzhj 123 7 and and CC cord-005646-xhx9pzhj 123 8 nursing nursing NN cord-005646-xhx9pzhj 123 9 staff staff NN cord-005646-xhx9pzhj 123 10 in in IN cord-005646-xhx9pzhj 123 11 pediatric pediatric JJ cord-005646-xhx9pzhj 123 12 ICUs icu NNS cord-005646-xhx9pzhj 123 13 are be VBP cord-005646-xhx9pzhj 123 14 likely likely JJ cord-005646-xhx9pzhj 123 15 to to TO cord-005646-xhx9pzhj 123 16 be be VB cord-005646-xhx9pzhj 123 17 better well JJR cord-005646-xhx9pzhj 123 18 at at IN cord-005646-xhx9pzhj 123 19 looking look VBG cord-005646-xhx9pzhj 123 20 ~fter ~ft JJR cord-005646-xhx9pzhj 123 21 children child NNS cord-005646-xhx9pzhj 123 22 , , , cord-005646-xhx9pzhj 123 23 and and CC cord-005646-xhx9pzhj 123 24 PlCU PlCU NNP cord-005646-xhx9pzhj 123 25 RMOs rmo NNS cord-005646-xhx9pzhj 123 26 have have VBP cord-005646-xhx9pzhj 123 27 greater great JJR cord-005646-xhx9pzhj 123 28 skills skill NNS cord-005646-xhx9pzhj 123 29 in in IN cord-005646-xhx9pzhj 123 30 pediatric pediatric JJ cord-005646-xhx9pzhj 123 31 intubation intubation NN cord-005646-xhx9pzhj 123 32 , , , cord-005646-xhx9pzhj 123 33 ventilation ventilation NN cord-005646-xhx9pzhj 123 34 , , , cord-005646-xhx9pzhj 123 35 IV IV NNP cord-005646-xhx9pzhj 123 36 drip drip NN cord-005646-xhx9pzhj 123 37 insertion insertion NN cord-005646-xhx9pzhj 123 38 and and CC cord-005646-xhx9pzhj 123 39 drug drug NN cord-005646-xhx9pzhj 123 40 doses dose NNS cord-005646-xhx9pzhj 123 41 . . . cord-005646-xhx9pzhj 124 1 PICUs picu NNS cord-005646-xhx9pzhj 124 2 are be VBP cord-005646-xhx9pzhj 124 3 more more RBR cord-005646-xhx9pzhj 124 4 likely likely JJ cord-005646-xhx9pzhj 124 5 to to TO cord-005646-xhx9pzhj 124 6 have have VB cord-005646-xhx9pzhj 124 7 appropriate appropriate JJ cord-005646-xhx9pzhj 124 8 equipment equipment NN cord-005646-xhx9pzhj 124 9 to to TO cord-005646-xhx9pzhj 124 10 manage manage VB cord-005646-xhx9pzhj 124 11 children child NNS cord-005646-xhx9pzhj 124 12 -especially -especially RB cord-005646-xhx9pzhj 124 13 for for IN cord-005646-xhx9pzhj 124 14 uncommon uncommon JJ cord-005646-xhx9pzhj 124 15 but but CC cord-005646-xhx9pzhj 124 16 life life NN cord-005646-xhx9pzhj 124 17 - - HYPH cord-005646-xhx9pzhj 124 18 threatening threaten VBG cord-005646-xhx9pzhj 124 19 situations situation NNS cord-005646-xhx9pzhj 124 20 . . . cord-005646-xhx9pzhj 125 1 ICUs ICUs NNP cord-005646-xhx9pzhj 125 2 in in IN cord-005646-xhx9pzhj 125 3 pediatric pediatric JJ cord-005646-xhx9pzhj 125 4 hospitals hospital NNS cord-005646-xhx9pzhj 125 5 are be VBP cord-005646-xhx9pzhj 125 6 more more RBR cord-005646-xhx9pzhj 125 7 likely likely JJ cord-005646-xhx9pzhj 125 8 to to TO cord-005646-xhx9pzhj 125 9 have have VB cord-005646-xhx9pzhj 125 10 physicians physician NNS cord-005646-xhx9pzhj 125 11 and and CC cord-005646-xhx9pzhj 125 12 surgeons surgeon NNS cord-005646-xhx9pzhj 125 13 with with IN cord-005646-xhx9pzhj 125 14 pediatric pediatric JJ cord-005646-xhx9pzhj 125 15 expertise expertise NN cord-005646-xhx9pzhj 125 16 available available JJ cord-005646-xhx9pzhj 125 17 for for IN cord-005646-xhx9pzhj 125 18 consultation consultation NN cord-005646-xhx9pzhj 125 19 at at IN cord-005646-xhx9pzhj 125 20 all all DT cord-005646-xhx9pzhj 125 21 times time NNS cord-005646-xhx9pzhj 125 22 . . . cord-005646-xhx9pzhj 126 1 The the DT cord-005646-xhx9pzhj 126 2 American American NNP cord-005646-xhx9pzhj 126 3 Academy Academy NNP cord-005646-xhx9pzhj 126 4 of of IN cord-005646-xhx9pzhj 126 5 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 126 6 , , , cord-005646-xhx9pzhj 126 7 the the DT cord-005646-xhx9pzhj 126 8 Society Society NNP cord-005646-xhx9pzhj 126 9 of of IN cord-005646-xhx9pzhj 126 10 Critical Critical NNP cord-005646-xhx9pzhj 126 11 Care Care NNP cord-005646-xhx9pzhj 126 12 Medicine Medicine NNP cord-005646-xhx9pzhj 126 13 , , , cord-005646-xhx9pzhj 126 14 the the DT cord-005646-xhx9pzhj 126 15 British British NNP cord-005646-xhx9pzhj 126 16 Paediatric Paediatric NNP cord-005646-xhx9pzhj 126 17 Association Association NNP cord-005646-xhx9pzhj 126 18 and and CC cord-005646-xhx9pzhj 126 19 the the DT cord-005646-xhx9pzhj 126 20 Australian australian JJ cord-005646-xhx9pzhj 126 21 NH&MRC NH&MRC NNP cord-005646-xhx9pzhj 126 22 have have VBP cord-005646-xhx9pzhj 126 23 all all DT cord-005646-xhx9pzhj 126 24 said say VBN cord-005646-xhx9pzhj 126 25 that that IN cord-005646-xhx9pzhj 126 26 children child NNS cord-005646-xhx9pzhj 126 27 should should MD cord-005646-xhx9pzhj 126 28 receive receive VB cord-005646-xhx9pzhj 126 29 intensive intensive JJ cord-005646-xhx9pzhj 126 30 care care NN cord-005646-xhx9pzhj 126 31 in'specialist in'specialist NN cord-005646-xhx9pzhj 126 32 pediatric pediatric JJ cord-005646-xhx9pzhj 126 33 units unit NNS cord-005646-xhx9pzhj 126 34 . . . cord-005646-xhx9pzhj 127 1 The the DT cord-005646-xhx9pzhj 127 2 weight weight NN cord-005646-xhx9pzhj 127 3 of of IN cord-005646-xhx9pzhj 127 4 authoritative authoritative JJ cord-005646-xhx9pzhj 127 5 opinion opinion NN cord-005646-xhx9pzhj 127 6 , , , cord-005646-xhx9pzhj 127 7 and and CC cord-005646-xhx9pzhj 127 8 direct direct JJ cord-005646-xhx9pzhj 127 9 and and CC cord-005646-xhx9pzhj 127 10 indirect indirect JJ cord-005646-xhx9pzhj 127 11 evidence evidence NN cord-005646-xhx9pzhj 127 12 is be VBZ cord-005646-xhx9pzhj 127 13 strongly strongly RB cord-005646-xhx9pzhj 127 14 in in IN cord-005646-xhx9pzhj 127 15 favour favour NN cord-005646-xhx9pzhj 127 16 of of IN cord-005646-xhx9pzhj 127 17 looking look VBG cord-005646-xhx9pzhj 127 18 after after IN cord-005646-xhx9pzhj 127 19 children child NNS cord-005646-xhx9pzhj 127 20 in in IN cord-005646-xhx9pzhj 127 21 dedicated dedicated JJ cord-005646-xhx9pzhj 127 22 pediatric pediatric JJ cord-005646-xhx9pzhj 127 23 ICUs icu NNS cord-005646-xhx9pzhj 127 24 . . . cord-005646-xhx9pzhj 128 1 neurological neurological JJ cord-005646-xhx9pzhj 128 2 deficit deficit NN cord-005646-xhx9pzhj 128 3 showed show VBD cord-005646-xhx9pzhj 128 4 higher high JJR cord-005646-xhx9pzhj 128 5 CBF CBF NNP cord-005646-xhx9pzhj 128 6 values value NNS cord-005646-xhx9pzhj 128 7 ( ( -LRB- cord-005646-xhx9pzhj 128 8 125.7/115.2 125.7/115.2 NN cord-005646-xhx9pzhj 128 9 ml/100g/ ml/100g/ NNS cord-005646-xhx9pzhj 128 10 rain rain NN cord-005646-xhx9pzhj 128 11 . . . cord-005646-xhx9pzhj 128 12 ) ) -RRB- cord-005646-xhx9pzhj 129 1 than than IN cord-005646-xhx9pzhj 129 2 the the DT cord-005646-xhx9pzhj 129 3 11 11 CD cord-005646-xhx9pzhj 129 4 patients patient NNS cord-005646-xhx9pzhj 129 5 with with IN cord-005646-xhx9pzhj 129 6 good good JJ cord-005646-xhx9pzhj 129 7 outcome outcome NN cord-005646-xhx9pzhj 129 8 ( ( -LRB- cord-005646-xhx9pzhj 129 9 mean mean VB cord-005646-xhx9pzhj 129 10 CBF CBF NNP cord-005646-xhx9pzhj 129 11 1 1 CD cord-005646-xhx9pzhj 129 12 17.5 17.5 CD cord-005646-xhx9pzhj 129 13 SD sd NN cord-005646-xhx9pzhj 129 14 +8.1 +8.1 NNP cord-005646-xhx9pzhj 129 15 ; ; : cord-005646-xhx9pzhj 129 16 CBF CBF NNP cord-005646-xhx9pzhj 129 17 2 2 CD cord-005646-xhx9pzhj 129 18 19.9 19.9 CD cord-005646-xhx9pzhj 129 19 SD sd NN cord-005646-xhx9pzhj 130 1 _ _ NNP cord-005646-xhx9pzhj 130 2 +9.1 +9.1 : cord-005646-xhx9pzhj 130 3 ml/100g ml/100g NN cord-005646-xhx9pzhj 130 4 / / SYM cord-005646-xhx9pzhj 130 5 rain rain NN cord-005646-xhx9pzhj 130 6 } } -RRB- cord-005646-xhx9pzhj 130 7 . . . cord-005646-xhx9pzhj 131 1 Discussion discussion NN cord-005646-xhx9pzhj 131 2 : : : cord-005646-xhx9pzhj 132 1 In in IN cord-005646-xhx9pzhj 132 2 asphyxia asphyxia NN cord-005646-xhx9pzhj 132 3 decrease decrease NN cord-005646-xhx9pzhj 132 4 of of IN cord-005646-xhx9pzhj 132 5 pH pH NNP cord-005646-xhx9pzhj 132 6 is be VBZ cord-005646-xhx9pzhj 132 7 due due JJ cord-005646-xhx9pzhj 132 8 to to IN cord-005646-xhx9pzhj 132 9 reduced reduce VBN cord-005646-xhx9pzhj 132 10 tissue tissue NN cord-005646-xhx9pzhj 132 11 oxygenation oxygenation NN cord-005646-xhx9pzhj 132 12 and and CC cord-005646-xhx9pzhj 132 13 indicates indicate VBZ cord-005646-xhx9pzhj 132 14 the the DT cord-005646-xhx9pzhj 132 15 severity severity NN cord-005646-xhx9pzhj 132 16 of of IN cord-005646-xhx9pzhj 132 17 metabolic metabolic JJ cord-005646-xhx9pzhj 132 18 derangements derangement NNS cord-005646-xhx9pzhj 132 19 . . . cord-005646-xhx9pzhj 133 1 CO2reactivity CO2reactivity NNP cord-005646-xhx9pzhj 133 2 in in IN cord-005646-xhx9pzhj 133 3 newborns newborn NNS cord-005646-xhx9pzhj 133 4 with with IN cord-005646-xhx9pzhj 133 5 perinatal perinatal JJ cord-005646-xhx9pzhj 133 6 asphyxia asphyxia NN cord-005646-xhx9pzhj 133 7 correlates correlate VBZ cord-005646-xhx9pzhj 133 8 with with IN cord-005646-xhx9pzhj 133 9 the the DT cord-005646-xhx9pzhj 133 10 lowest low JJS cord-005646-xhx9pzhj 133 11 pH ph NN cord-005646-xhx9pzhj 133 12 and and CC cord-005646-xhx9pzhj 133 13 therefore therefore RB cord-005646-xhx9pzhj 133 14 may may MD cord-005646-xhx9pzhj 133 15 reflect reflect VB cord-005646-xhx9pzhj 133 16 severity severity NN cord-005646-xhx9pzhj 133 17 of of IN cord-005646-xhx9pzhj 133 18 asphyxia asphyxia NN cord-005646-xhx9pzhj 133 19 . . . cord-005646-xhx9pzhj 134 1 Continuous continuous JJ cord-005646-xhx9pzhj 134 2 monitoring monitoring NN cord-005646-xhx9pzhj 134 3 of of IN cord-005646-xhx9pzhj 134 4 cerebral cerebral JJ cord-005646-xhx9pzhj 134 5 activity activity NN cord-005646-xhx9pzhj 134 6 is be VBZ cord-005646-xhx9pzhj 134 7 carried carry VBN cord-005646-xhx9pzhj 134 8 out out RP cord-005646-xhx9pzhj 134 9 in in IN cord-005646-xhx9pzhj 134 10 our -PRON- PRP$ cord-005646-xhx9pzhj 134 11 unit unit NN cord-005646-xhx9pzhj 134 12 on on IN cord-005646-xhx9pzhj 134 13 all all DT cord-005646-xhx9pzhj 134 14 admissions admission NNS cord-005646-xhx9pzhj 134 15 at at IN cord-005646-xhx9pzhj 134 16 risk risk NN cord-005646-xhx9pzhj 134 17 of of IN cord-005646-xhx9pzhj 134 18 cerebral cerebral JJ cord-005646-xhx9pzhj 134 19 dysfunction dysfunction NN cord-005646-xhx9pzhj 134 20 , , , cord-005646-xhx9pzhj 134 21 A a DT cord-005646-xhx9pzhj 134 22 number number NN cord-005646-xhx9pzhj 134 23 of of IN cord-005646-xhx9pzhj 134 24 monitors monitor NNS cord-005646-xhx9pzhj 134 25 are be VBP cord-005646-xhx9pzhj 134 26 commercially commercially RB cord-005646-xhx9pzhj 134 27 available available JJ cord-005646-xhx9pzhj 134 28 and and CC cord-005646-xhx9pzhj 134 29 we -PRON- PRP cord-005646-xhx9pzhj 134 30 report report VBP cord-005646-xhx9pzhj 134 31 our -PRON- PRP$ cord-005646-xhx9pzhj 134 32 experience experience NN cord-005646-xhx9pzhj 134 33 with with IN cord-005646-xhx9pzhj 134 34 the the DT cord-005646-xhx9pzhj 134 35 CFAM2 cfam2 NN cord-005646-xhx9pzhj 134 36 which which WDT cord-005646-xhx9pzhj 134 37 provides provide VBZ cord-005646-xhx9pzhj 134 38 in in IN cord-005646-xhx9pzhj 134 39 addition addition NN cord-005646-xhx9pzhj 134 40 to to TO cord-005646-xhx9pzhj 134 41 amplitude amplitude VB cord-005646-xhx9pzhj 134 42 integrated integrate VBN cord-005646-xhx9pzhj 134 43 EEG EEG NNP cord-005646-xhx9pzhj 134 44 analysis analysis NN cord-005646-xhx9pzhj 134 45 , , , cord-005646-xhx9pzhj 134 46 continuous continuous JJ cord-005646-xhx9pzhj 134 47 raw raw JJ cord-005646-xhx9pzhj 134 48 EEG EEG NNP cord-005646-xhx9pzhj 134 49 display display NN cord-005646-xhx9pzhj 134 50 and and CC cord-005646-xhx9pzhj 134 51 frequency frequency NN cord-005646-xhx9pzhj 134 52 distribution distribution NN cord-005646-xhx9pzhj 134 53 . . . cord-005646-xhx9pzhj 135 1 Bilateral bilateral JJ cord-005646-xhx9pzhj 135 2 recordings recording NNS cord-005646-xhx9pzhj 135 3 are be VBP cord-005646-xhx9pzhj 135 4 commenced commence VBN cord-005646-xhx9pzhj 135 5 as as RB cord-005646-xhx9pzhj 135 6 soon soon RB cord-005646-xhx9pzhj 135 7 as as IN cord-005646-xhx9pzhj 135 8 possible possible JJ cord-005646-xhx9pzhj 135 9 and and CC cord-005646-xhx9pzhj 135 10 continued continue VBD cord-005646-xhx9pzhj 135 11 while while IN cord-005646-xhx9pzhj 135 12 clinically clinically RB cord-005646-xhx9pzhj 135 13 indicated indicate VBN cord-005646-xhx9pzhj 135 14 . . . cord-005646-xhx9pzhj 136 1 Forty forty CD cord-005646-xhx9pzhj 136 2 one one CD cord-005646-xhx9pzhj 136 3 children child NNS cord-005646-xhx9pzhj 136 4 ranging range VBG cord-005646-xhx9pzhj 136 5 in in IN cord-005646-xhx9pzhj 136 6 ages age NNS cord-005646-xhx9pzhj 136 7 from from IN cord-005646-xhx9pzhj 136 8 4 4 CD cord-005646-xhx9pzhj 136 9 weeks week NNS cord-005646-xhx9pzhj 136 10 to to IN cord-005646-xhx9pzhj 136 11 16 16 CD cord-005646-xhx9pzhj 136 12 years year NNS cord-005646-xhx9pzhj 136 13 were be VBD cord-005646-xhx9pzhj 136 14 monitored monitor VBN cord-005646-xhx9pzhj 136 15 for for IN cord-005646-xhx9pzhj 136 16 periods period NNS cord-005646-xhx9pzhj 136 17 from from IN cord-005646-xhx9pzhj 136 18 3 3 CD cord-005646-xhx9pzhj 136 19 hours hour NNS cord-005646-xhx9pzhj 136 20 to to IN cord-005646-xhx9pzhj 136 21 I0 i0 NN cord-005646-xhx9pzhj 136 22 days day NNS cord-005646-xhx9pzhj 136 23 , , , cord-005646-xhx9pzhj 136 24 Diagnoses diagnosis NNS cord-005646-xhx9pzhj 136 25 included include VBD cord-005646-xhx9pzhj 136 26 traumatic traumatic JJ cord-005646-xhx9pzhj 136 27 brain brain NN cord-005646-xhx9pzhj 136 28 injury injury NN cord-005646-xhx9pzhj 136 29 ( ( -LRB- cord-005646-xhx9pzhj 136 30 11 11 CD cord-005646-xhx9pzhj 136 31 ) ) -RRB- cord-005646-xhx9pzhj 136 32 , , , cord-005646-xhx9pzhj 136 33 sepsis sepsis NN cord-005646-xhx9pzhj 136 34 / / SYM cord-005646-xhx9pzhj 136 35 meningitis meningitis NN cord-005646-xhx9pzhj 136 36 / / , cord-005646-xhx9pzhj 136 37 encephalitis encephalitis NN cord-005646-xhx9pzhj 136 38 ( ( -LRB- cord-005646-xhx9pzhj 136 39 1 1 CD cord-005646-xhx9pzhj 136 40 t t NN cord-005646-xhx9pzhj 136 41 ) ) -RRB- cord-005646-xhx9pzhj 136 42 , , , cord-005646-xhx9pzhj 136 43 status status NN cord-005646-xhx9pzhj 136 44 epilepticus epilepticus NN cord-005646-xhx9pzhj 136 45 ( ( -LRB- cord-005646-xhx9pzhj 136 46 8) 8) NNP cord-005646-xhx9pzhj 136 47 and and CC cord-005646-xhx9pzhj 136 48 miscellanous miscellanous NNP cord-005646-xhx9pzhj 136 49 others other NNS cord-005646-xhx9pzhj 136 50 ( ( -LRB- cord-005646-xhx9pzhj 136 51 11 11 CD cord-005646-xhx9pzhj 136 52 ) ) -RRB- cord-005646-xhx9pzhj 136 53 . . . cord-005646-xhx9pzhj 137 1 Results result NNS cord-005646-xhx9pzhj 137 2 are be VBP cord-005646-xhx9pzhj 137 3 tabulated tabulate VBN cord-005646-xhx9pzhj 137 4 below below RB cord-005646-xhx9pzhj 137 5 . . . cord-005646-xhx9pzhj 138 1 Patients patient NNS cord-005646-xhx9pzhj 138 2 13 13 CD cord-005646-xhx9pzhj 138 3 12 12 CD cord-005646-xhx9pzhj 138 4 16 16 CD cord-005646-xhx9pzhj 138 5 Status Status NNP cord-005646-xhx9pzhj 138 6 epilepticus epilepticus NN cord-005646-xhx9pzhj 138 7 10 10 CD cord-005646-xhx9pzhj 138 8 4 4 CD cord-005646-xhx9pzhj 138 9 1 1 CD cord-005646-xhx9pzhj 139 1 * * NFP cord-005646-xhx9pzhj 139 2 Beta beta NN cord-005646-xhx9pzhj 139 3 activity activity NN cord-005646-xhx9pzhj 139 4 1 1 CD cord-005646-xhx9pzhj 139 5 8 8 CD cord-005646-xhx9pzhj 139 6 15 15 CD cord-005646-xhx9pzhj 140 1 * * NFP cord-005646-xhx9pzhj 140 2 Background background NN cord-005646-xhx9pzhj 140 3 voltage voltage VB cord-005646-xhx9pzhj 140 4 10 10 CD cord-005646-xhx9pzhj 140 5 3 3 CD cord-005646-xhx9pzhj 140 6 1 1 CD cord-005646-xhx9pzhj 141 1 * * NFP cord-005646-xhx9pzhj 141 2 < < XX cord-005646-xhx9pzhj 142 1 I -PRON- PRP cord-005646-xhx9pzhj 142 2 O o UH cord-005646-xhx9pzhj 143 1 /zV /zv CD cord-005646-xhx9pzhj 143 2 2 2 CD cord-005646-xhx9pzhj 143 3 or or CC cord-005646-xhx9pzhj 143 4 more more JJR cord-005646-xhx9pzhj 143 5 of of IN cord-005646-xhx9pzhj 143 6 above above IN cord-005646-xhx9pzhj 143 7 12 12 CD cord-005646-xhx9pzhj 143 8 2 2 CD cord-005646-xhx9pzhj 143 9 1 1 CD cord-005646-xhx9pzhj 144 1 * * NFP cord-005646-xhx9pzhj 144 2 ( ( -LRB- cord-005646-xhx9pzhj 144 3 * * NFP cord-005646-xhx9pzhj 144 4 Z2 z2 NN cord-005646-xhx9pzhj 144 5 p p NN cord-005646-xhx9pzhj 144 6 < < XX cord-005646-xhx9pzhj 144 7 0,001 0,001 CD cord-005646-xhx9pzhj 144 8 ) ) -RRB- cord-005646-xhx9pzhj 144 9 Asymmetry asymmetry NN cord-005646-xhx9pzhj 144 10 developed develop VBD cord-005646-xhx9pzhj 144 11 in in IN cord-005646-xhx9pzhj 144 12 4 4 CD cord-005646-xhx9pzhj 144 13 children child NNS cord-005646-xhx9pzhj 144 14 , , , cord-005646-xhx9pzhj 144 15 all all DT cord-005646-xhx9pzhj 144 16 of of IN cord-005646-xhx9pzhj 144 17 whom whom WP cord-005646-xhx9pzhj 144 18 died die VBD cord-005646-xhx9pzhj 144 19 . . . cord-005646-xhx9pzhj 145 1 Positive positive JJ cord-005646-xhx9pzhj 145 2 predictors predictor NNS cord-005646-xhx9pzhj 145 3 of of IN cord-005646-xhx9pzhj 145 4 good good JJ cord-005646-xhx9pzhj 145 5 outcome outcome NN cord-005646-xhx9pzhj 145 6 included include VBD cord-005646-xhx9pzhj 145 7 a a DT cord-005646-xhx9pzhj 145 8 mean mean JJ cord-005646-xhx9pzhj 145 9 background background NN cord-005646-xhx9pzhj 145 10 activity activity NN cord-005646-xhx9pzhj 145 11 of of IN cord-005646-xhx9pzhj 145 12 > > XX cord-005646-xhx9pzhj 145 13 10zzV 10zzv CD cord-005646-xhx9pzhj 145 14 , , , cord-005646-xhx9pzhj 145 15 the the DT cord-005646-xhx9pzhj 145 16 presence presence NN cord-005646-xhx9pzhj 145 17 of of IN cord-005646-xhx9pzhj 145 18 faster fast JJR cord-005646-xhx9pzhj 145 19 frequencies frequency NNS cord-005646-xhx9pzhj 145 20 ( ( -LRB- cord-005646-xhx9pzhj 145 21 usually usually RB cord-005646-xhx9pzhj 145 22 13 13 CD cord-005646-xhx9pzhj 145 23 ) ) -RRB- cord-005646-xhx9pzhj 145 24 in in IN cord-005646-xhx9pzhj 145 25 response response NN cord-005646-xhx9pzhj 145 26 to to IN cord-005646-xhx9pzhj 145 27 sedative sedative JJ cord-005646-xhx9pzhj 145 28 drugs drug NNS cord-005646-xhx9pzhj 145 29 and and CC cord-005646-xhx9pzhj 145 30 the the DT cord-005646-xhx9pzhj 145 31 absence absence NN cord-005646-xhx9pzhj 145 32 of of IN cord-005646-xhx9pzhj 145 33 seizures seizure NNS cord-005646-xhx9pzhj 145 34 . . . cord-005646-xhx9pzhj 146 1 All all DT cord-005646-xhx9pzhj 146 2 monitoring monitoring NN cord-005646-xhx9pzhj 146 3 is be VBZ cord-005646-xhx9pzhj 146 4 performed perform VBN cord-005646-xhx9pzhj 146 5 by by IN cord-005646-xhx9pzhj 146 6 the the DT cord-005646-xhx9pzhj 146 7 PICU PICU NNP cord-005646-xhx9pzhj 146 8 staff staff NN cord-005646-xhx9pzhj 146 9 and and CC cord-005646-xhx9pzhj 146 10 increasing increase VBG cord-005646-xhx9pzhj 146 11 expertise expertise NN cord-005646-xhx9pzhj 146 12 in in IN cord-005646-xhx9pzhj 146 13 interpretation interpretation NN cord-005646-xhx9pzhj 146 14 has have VBZ cord-005646-xhx9pzhj 146 15 resulted result VBN cord-005646-xhx9pzhj 146 16 in in IN cord-005646-xhx9pzhj 146 17 earlier early RBR cord-005646-xhx9pzhj 146 18 therapeutic therapeutic JJ cord-005646-xhx9pzhj 146 19 and and CC cord-005646-xhx9pzhj 146 20 diagnostic diagnostic JJ cord-005646-xhx9pzhj 146 21 interventions intervention NNS cord-005646-xhx9pzhj 146 22 . . . cord-005646-xhx9pzhj 147 1 Regional regional JJ cord-005646-xhx9pzhj 148 1 It -PRON- PRP cord-005646-xhx9pzhj 148 2 was be VBD cord-005646-xhx9pzhj 148 3 previously previously RB cord-005646-xhx9pzhj 148 4 found find VBN cord-005646-xhx9pzhj 148 5 that that IN cord-005646-xhx9pzhj 148 6 histamine histamine NN cord-005646-xhx9pzhj 148 7 , , , cord-005646-xhx9pzhj 148 8 a a DT cord-005646-xhx9pzhj 148 9 vasoactive vasoactive JJ cord-005646-xhx9pzhj 148 10 mediator mediator NN cord-005646-xhx9pzhj 148 11 , , , cord-005646-xhx9pzhj 148 12 accumulated accumulate VBN cord-005646-xhx9pzhj 148 13 in in IN cord-005646-xhx9pzhj 148 14 brain brain NN cord-005646-xhx9pzhj 148 15 compartments compartment NNS cord-005646-xhx9pzhj 148 16 ( ( -LRB- cord-005646-xhx9pzhj 148 17 Kov Kov NNP cord-005646-xhx9pzhj 148 18 ~ ~ NFP cord-005646-xhx9pzhj 148 19 ics ics NNP cord-005646-xhx9pzhj 148 20 et et FW cord-005646-xhx9pzhj 148 21 aL aL NNP cord-005646-xhx9pzhj 148 22 1995 1995 CD cord-005646-xhx9pzhj 149 1 Neurosci Neurosci NNP cord-005646-xhx9pzhj 149 2 Lett Lett NNP cord-005646-xhx9pzhj 149 3 195:25 195:25 CD cord-005646-xhx9pzhj 149 4 ) ) -RRB- cord-005646-xhx9pzhj 149 5 , , , cord-005646-xhx9pzhj 149 6 and and CC cord-005646-xhx9pzhj 149 7 antihistamines antihistamine NNS cord-005646-xhx9pzhj 149 8 prevented prevent VBD cord-005646-xhx9pzhj 149 9 brain brain NN cord-005646-xhx9pzhj 149 10 edema edema NN cord-005646-xhx9pzhj 149 11 formation formation NN cord-005646-xhx9pzhj 149 12 ( ( -LRB- cord-005646-xhx9pzhj 149 13 Dux Dux NNP cord-005646-xhx9pzhj 149 14 et et FW cord-005646-xhx9pzhj 149 15 al al NNP cord-005646-xhx9pzhj 149 16 . . NNP cord-005646-xhx9pzhj 149 17 1987 1987 CD cord-005646-xhx9pzhj 149 18 Neuroscience Neuroscience NNP cord-005646-xhx9pzhj 149 19 22:317 22:317 CD cord-005646-xhx9pzhj 149 20 ) ) -RRB- cord-005646-xhx9pzhj 149 21 in in IN cord-005646-xhx9pzhj 149 22 asphyxiated asphyxiate VBN cord-005646-xhx9pzhj 149 23 newborn newborn JJ cord-005646-xhx9pzhj 149 24 pigs pig NNS cord-005646-xhx9pzhj 149 25 . . . cord-005646-xhx9pzhj 150 1 In in IN cord-005646-xhx9pzhj 150 2 the the DT cord-005646-xhx9pzhj 150 3 present present JJ cord-005646-xhx9pzhj 150 4 study study NN cord-005646-xhx9pzhj 150 5 we -PRON- PRP cord-005646-xhx9pzhj 150 6 investigated investigate VBD cord-005646-xhx9pzhj 150 7 the the DT cord-005646-xhx9pzhj 150 8 effect effect NN cord-005646-xhx9pzhj 150 9 of of IN cord-005646-xhx9pzhj 150 10 intracarotid intracarotid JJ cord-005646-xhx9pzhj 150 11 histamine histamine NN cord-005646-xhx9pzhj 150 12 injection injection NN cord-005646-xhx9pzhj 150 13 on on IN cord-005646-xhx9pzhj 150 14 the the DT cord-005646-xhx9pzhj 150 15 blood blood NN cord-005646-xhx9pzhj 150 16 - - HYPH cord-005646-xhx9pzhj 150 17 brain brain NN cord-005646-xhx9pzhj 150 18 barrier barrier NN cord-005646-xhx9pzhj 150 19 ( ( -LRB- cord-005646-xhx9pzhj 150 20 BBB BBB NNP cord-005646-xhx9pzhj 150 21 ) ) -RRB- cord-005646-xhx9pzhj 150 22 permeability permeability NN cord-005646-xhx9pzhj 150 23 , , , cord-005646-xhx9pzhj 150 24 Left leave VBN cord-005646-xhx9pzhj 150 25 internal internal JJ cord-005646-xhx9pzhj 150 26 carotid carotid JJ cord-005646-xhx9pzhj 150 27 artery artery NN cord-005646-xhx9pzhj 150 28 of of IN cord-005646-xhx9pzhj 150 29 30 30 CD cord-005646-xhx9pzhj 150 30 newborn newborn JJ cord-005646-xhx9pzhj 150 31 pigs pig NNS cord-005646-xhx9pzhj 150 32 ( ( -LRB- cord-005646-xhx9pzhj 150 33 4 4 CD cord-005646-xhx9pzhj 150 34 - - SYM cord-005646-xhx9pzhj 150 35 8 8 CD cord-005646-xhx9pzhj 150 36 h h NN cord-005646-xhx9pzhj 150 37 ; ; : cord-005646-xhx9pzhj 150 38 1,180 1,180 CD cord-005646-xhx9pzhj 150 39 - - SYM cord-005646-xhx9pzhj 150 40 1,530 1,530 CD cord-005646-xhx9pzhj 150 41 g g NN cord-005646-xhx9pzhj 150 42 ; ; : cord-005646-xhx9pzhj 150 43 ketamine ketamine NNP cord-005646-xhx9pzhj 150 44 anesthesia anesthesia NNP cord-005646-xhx9pzhj 150 45 , , , cord-005646-xhx9pzhj 150 46 10 10 CD cord-005646-xhx9pzhj 150 47 mg mg NN cord-005646-xhx9pzhj 150 48 x x SYM cord-005646-xhx9pzhj 150 49 kg kg NNP cord-005646-xhx9pzhj 150 50 4 4 CD cord-005646-xhx9pzhj 150 51 ) ) -RRB- cord-005646-xhx9pzhj 150 52 was be VBD cord-005646-xhx9pzhj 150 53 catheterized catheterize VBN cord-005646-xhx9pzhj 150 54 through through IN cord-005646-xhx9pzhj 150 55 the the DT cord-005646-xhx9pzhj 150 56 external external JJ cord-005646-xhx9pzhj 150 57 branch branch NN cord-005646-xhx9pzhj 150 58 and and CC cord-005646-xhx9pzhj 150 59 different different JJ cord-005646-xhx9pzhj 150 60 doses dose NNS cord-005646-xhx9pzhj 150 61 of of IN cord-005646-xhx9pzhj 150 62 histamine histamine NN cord-005646-xhx9pzhj 150 63 ( ( -LRB- cord-005646-xhx9pzhj 150 64 0 0 CD cord-005646-xhx9pzhj 150 65 , , , cord-005646-xhx9pzhj 150 66 10 10 CD cord-005646-xhx9pzhj 150 67 -6 -6 NNP cord-005646-xhx9pzhj 150 68 , , , cord-005646-xhx9pzhj 150 69 5xi0 5xi0 CD cord-005646-xhx9pzhj 150 70 -6 -6 NNP cord-005646-xhx9pzhj 150 71 , , , cord-005646-xhx9pzhj 150 72 10 10 CD cord-005646-xhx9pzhj 150 73 -5 -5 CD cord-005646-xhx9pzhj 150 74 , , , cord-005646-xhx9pzhj 150 75 5x104 5x104 CD cord-005646-xhx9pzhj 150 76 , , , cord-005646-xhx9pzhj 150 77 104 104 CD cord-005646-xhx9pzhj 150 78 M M NNP cord-005646-xhx9pzhj 150 79 , , , cord-005646-xhx9pzhj 150 80 respectively respectively RB cord-005646-xhx9pzhj 150 81 , , , cord-005646-xhx9pzhj 150 82 in in IN cord-005646-xhx9pzhj 150 83 6 6 CD cord-005646-xhx9pzhj 150 84 groups group NNS cord-005646-xhx9pzhj 150 85 of of IN cord-005646-xhx9pzhj 150 86 animals animal NNS cord-005646-xhx9pzhj 150 87 ; ; : cord-005646-xhx9pzhj 150 88 n=5 n=5 RB cord-005646-xhx9pzhj 150 89 in in IN cord-005646-xhx9pzhj 150 90 each each DT cord-005646-xhx9pzhj 150 91 ) ) -RRB- cord-005646-xhx9pzhj 150 92 diluted dilute VBN cord-005646-xhx9pzhj 150 93 in in IN cord-005646-xhx9pzhj 150 94 1.0 1.0 CD cord-005646-xhx9pzhj 150 95 ml ml NN cord-005646-xhx9pzhj 150 96 isotonic isotonic JJ cord-005646-xhx9pzhj 150 97 saline saline NN cord-005646-xhx9pzhj 150 98 was be VBD cord-005646-xhx9pzhj 150 99 injected inject VBN cord-005646-xhx9pzhj 150 100 into into IN cord-005646-xhx9pzhj 150 101 the the DT cord-005646-xhx9pzhj 150 102 vessel vessel NN cord-005646-xhx9pzhj 150 103 through through IN cord-005646-xhx9pzhj 150 104 1 1 CD cord-005646-xhx9pzhj 150 105 rain rain NN cord-005646-xhx9pzhj 150 106 . . . cord-005646-xhx9pzhj 151 1 BBB BBB NNP cord-005646-xhx9pzhj 151 2 permeability permeability NN cord-005646-xhx9pzhj 151 3 was be VBD cord-005646-xhx9pzhj 151 4 determined determine VBN cord-005646-xhx9pzhj 151 5 for for IN cord-005646-xhx9pzhj 151 6 a a DT cord-005646-xhx9pzhj 151 7 small small JJ cord-005646-xhx9pzhj 151 8 ( ( -LRB- cord-005646-xhx9pzhj 151 9 sodium sodium NN cord-005646-xhx9pzhj 151 10 fluorescein fluorescein NN cord-005646-xhx9pzhj 151 11 , , , cord-005646-xhx9pzhj 151 12 SF SF NNP cord-005646-xhx9pzhj 151 13 , , , cord-005646-xhx9pzhj 151 14 376 376 CD cord-005646-xhx9pzhj 151 15 Da Da NNP cord-005646-xhx9pzhj 151 16 ) ) -RRB- cord-005646-xhx9pzhj 151 17 and and CC cord-005646-xhx9pzhj 151 18 a a DT cord-005646-xhx9pzhj 151 19 large large JJ cord-005646-xhx9pzhj 151 20 ( ( -LRB- cord-005646-xhx9pzhj 151 21 Evans Evans NNP cord-005646-xhx9pzhj 151 22 blue blue JJ cord-005646-xhx9pzhj 151 23 / / SYM cord-005646-xhx9pzhj 151 24 albumin albumin NN cord-005646-xhx9pzhj 151 25 , , , cord-005646-xhx9pzhj 151 26 EBA EBA NNP cord-005646-xhx9pzhj 151 27 , , , cord-005646-xhx9pzhj 151 28 67 67 CD cord-005646-xhx9pzhj 151 29 kDa kDa NNS cord-005646-xhx9pzhj 151 30 ) ) -RRB- cord-005646-xhx9pzhj 151 31 tracer tracer NNP cord-005646-xhx9pzhj 151 32 ( ( -LRB- cord-005646-xhx9pzhj 151 33 2 2 CD cord-005646-xhx9pzhj 151 34 % % NN cord-005646-xhx9pzhj 151 35 , , , cord-005646-xhx9pzhj 151 36 5 5 CD cord-005646-xhx9pzhj 151 37 mLxkg mLxkg NNP cord-005646-xhx9pzhj 151 38 4 4 CD cord-005646-xhx9pzhj 151 39 , , , cord-005646-xhx9pzhj 151 40 30 30 CD cord-005646-xhx9pzhj 151 41 rain rain NN cord-005646-xhx9pzhj 151 42 circulation circulation NN cord-005646-xhx9pzhj 151 43 time time NN cord-005646-xhx9pzhj 151 44 for for IN cord-005646-xhx9pzhj 151 45 both both DT cord-005646-xhx9pzhj 151 46 dyes dye NNS cord-005646-xhx9pzhj 151 47 ) ) -RRB- cord-005646-xhx9pzhj 151 48 concomitantly concomitantly RB cord-005646-xhx9pzhj 151 49 in in IN cord-005646-xhx9pzhj 151 50 frontal frontal JJ cord-005646-xhx9pzhj 151 51 , , , cord-005646-xhx9pzhj 151 52 parietal parietal JJ cord-005646-xhx9pzhj 151 53 and and CC cord-005646-xhx9pzhj 151 54 occipital occipital JJ cord-005646-xhx9pzhj 151 55 cortex cortex NNP cord-005646-xhx9pzhj 151 56 , , , cord-005646-xhx9pzhj 151 57 hippocampus hippocampus NN cord-005646-xhx9pzhj 151 58 , , , cord-005646-xhx9pzhj 151 59 and and CC cord-005646-xhx9pzhj 151 60 periventrieular periventrieular NNP cord-005646-xhx9pzhj 151 61 white white JJ cord-005646-xhx9pzhj 151 62 matter matter NN cord-005646-xhx9pzhj 151 63 both both DT cord-005646-xhx9pzhj 151 64 on on IN cord-005646-xhx9pzhj 151 65 left left JJ cord-005646-xhx9pzhj 151 66 and and CC cord-005646-xhx9pzhj 151 67 right right JJ cord-005646-xhx9pzhj 151 68 sides side NNS cord-005646-xhx9pzhj 151 69 1 1 CD cord-005646-xhx9pzhj 151 70 h h NN cord-005646-xhx9pzhj 151 71 after after IN cord-005646-xhx9pzhj 151 72 the the DT cord-005646-xhx9pzhj 151 73 challenge challenge NN cord-005646-xhx9pzhj 151 74 . . . cord-005646-xhx9pzhj 152 1 Then then RB cord-005646-xhx9pzhj 152 2 , , , cord-005646-xhx9pzhj 152 3 intravascular intravascular JJ cord-005646-xhx9pzhj 152 4 dyes dye NNS cord-005646-xhx9pzhj 152 5 were be VBD cord-005646-xhx9pzhj 152 6 removed remove VBN cord-005646-xhx9pzhj 152 7 by by IN cord-005646-xhx9pzhj 152 8 perfusion perfusion NN cord-005646-xhx9pzhj 152 9 and and CC cord-005646-xhx9pzhj 152 10 BBB bbb NN cord-005646-xhx9pzhj 152 11 permeability permeability NN cord-005646-xhx9pzhj 152 12 for for IN cord-005646-xhx9pzhj 152 13 both both DT cord-005646-xhx9pzhj 152 14 tracers tracer NNS cord-005646-xhx9pzhj 152 15 was be VBD cord-005646-xhx9pzhj 152 16 quantified quantify VBN cord-005646-xhx9pzhj 152 17 by by IN cord-005646-xhx9pzhj 152 18 fluorescence fluorescence NN cord-005646-xhx9pzhj 152 19 spectrophotometry spectrophotometry NN cord-005646-xhx9pzhj 152 20 ( ( -LRB- cord-005646-xhx9pzhj 152 21 wavelengths wavelength NNS cord-005646-xhx9pzhj 152 22 for for IN cord-005646-xhx9pzhj 152 23 excitation excitation NN cord-005646-xhx9pzhj 152 24 and and CC cord-005646-xhx9pzhj 152 25 emission emission NN cord-005646-xhx9pzhj 152 26 were be VBD cord-005646-xhx9pzhj 152 27 440 440 CD cord-005646-xhx9pzhj 152 28 nm nm NN cord-005646-xhx9pzhj 152 29 and and CC cord-005646-xhx9pzhj 152 30 525 525 CD cord-005646-xhx9pzhj 152 31 nm nm NN cord-005646-xhx9pzhj 152 32 for for IN cord-005646-xhx9pzhj 152 33 SF SF NNP cord-005646-xhx9pzhj 152 34 ; ; : cord-005646-xhx9pzhj 152 35 and and CC cord-005646-xhx9pzhj 152 36 620 620 CD cord-005646-xhx9pzhj 152 37 nm nm NN cord-005646-xhx9pzhj 152 38 and and CC cord-005646-xhx9pzhj 152 39 680 680 CD cord-005646-xhx9pzhj 152 40 nm nm NN cord-005646-xhx9pzhj 152 41 for for IN cord-005646-xhx9pzhj 152 42 EBA EBA NNP cord-005646-xhx9pzhj 152 43 , , , cord-005646-xhx9pzhj 152 44 respectively respectively RB cord-005646-xhx9pzhj 152 45 ) ) -RRB- cord-005646-xhx9pzhj 152 46 . . . cord-005646-xhx9pzhj 153 1 Histamine histamine NN cord-005646-xhx9pzhj 153 2 injection injection NN cord-005646-xhx9pzhj 153 3 , , , cord-005646-xhx9pzhj 153 4 in in IN cord-005646-xhx9pzhj 153 5 doses dose NNS cord-005646-xhx9pzhj 153 6 higher high JJR cord-005646-xhx9pzhj 153 7 than than IN cord-005646-xhx9pzhj 153 8 10 10 CD cord-005646-xhx9pzhj 154 1 .6 .6 NFP cord-005646-xhx9pzhj 154 2 M M NNP cord-005646-xhx9pzhj 154 3 , , , cord-005646-xhx9pzhj 154 4 significantly significantly RB cord-005646-xhx9pzhj 154 5 ( ( -LRB- cord-005646-xhx9pzhj 154 6 P<0.05 P<0.05 NNS cord-005646-xhx9pzhj 154 7 ; ; : cord-005646-xhx9pzhj 154 8 Kruskal Kruskal NNP cord-005646-xhx9pzhj 154 9 - - HYPH cord-005646-xhx9pzhj 154 10 Wallis Wallis NNP cord-005646-xhx9pzhj 154 11 one one CD cord-005646-xhx9pzhj 154 12 way way NN cord-005646-xhx9pzhj 154 13 ANOVA ANOVA NNP cord-005646-xhx9pzhj 154 14 on on IN cord-005646-xhx9pzhj 154 15 ranks rank NNS cord-005646-xhx9pzhj 154 16 followed follow VBN cord-005646-xhx9pzhj 154 17 by by IN cord-005646-xhx9pzhj 154 18 Dunn Dunn NNP cord-005646-xhx9pzhj 154 19 's 's POS cord-005646-xhx9pzhj 154 20 test test NN cord-005646-xhx9pzhj 154 21 ) ) -RRB- cord-005646-xhx9pzhj 154 22 increased increase VBD cord-005646-xhx9pzhj 154 23 BBB BBB NNP cord-005646-xhx9pzhj 154 24 permeability permeability NN cord-005646-xhx9pzhj 154 25 for for IN cord-005646-xhx9pzhj 154 26 both both DT cord-005646-xhx9pzhj 154 27 tracers tracer NNS cord-005646-xhx9pzhj 154 28 in in IN cord-005646-xhx9pzhj 154 29 each each DT cord-005646-xhx9pzhj 154 30 brain brain NN cord-005646-xhx9pzhj 154 31 region region NN cord-005646-xhx9pzhj 154 32 . . . cord-005646-xhx9pzhj 155 1 Changes change NNS cord-005646-xhx9pzhj 155 2 in in IN cord-005646-xhx9pzhj 155 3 left left JJ cord-005646-xhx9pzhj 155 4 hemisphere hemisphere NN cord-005646-xhx9pzhj 155 5 were be VBD cord-005646-xhx9pzhj 155 6 more more RBR cord-005646-xhx9pzhj 155 7 intense intense JJ cord-005646-xhx9pzhj 155 8 ( ( -LRB- cord-005646-xhx9pzhj 155 9 P<0.05 P<0.05 NNS cord-005646-xhx9pzhj 155 10 ) ) -RRB- cord-005646-xhx9pzhj 155 11 than than IN cord-005646-xhx9pzhj 155 12 those those DT cord-005646-xhx9pzhj 155 13 in in IN cord-005646-xhx9pzhj 155 14 right right JJ cord-005646-xhx9pzhj 155 15 one one CD cord-005646-xhx9pzhj 155 16 after after IN cord-005646-xhx9pzhj 155 17 the the DT cord-005646-xhx9pzhj 155 18 doses dose NNS cord-005646-xhx9pzhj 155 19 of of IN cord-005646-xhx9pzhj 155 20 5xi0 5xi0 CD cord-005646-xhx9pzhj 155 21 -6 -6 CD cord-005646-xhx9pzhj 155 22 and and CC cord-005646-xhx9pzhj 155 23 10 10 CD cord-005646-xhx9pzhj 155 24 -5 -5 NNP cord-005646-xhx9pzhj 155 25 M M NNP cord-005646-xhx9pzhj 155 26 in in IN cord-005646-xhx9pzhj 155 27 each each DT cord-005646-xhx9pzhj 155 28 region region NN cord-005646-xhx9pzhj 155 29 , , , cord-005646-xhx9pzhj 155 30 i0 i0 NN cord-005646-xhx9pzhj 155 31 4 4 CD cord-005646-xhx9pzhj 155 32 M M NNP cord-005646-xhx9pzhj 155 33 histamine histamine NN cord-005646-xhx9pzhj 155 34 administration administration NN cord-005646-xhx9pzhj 155 35 induced induce VBD cord-005646-xhx9pzhj 155 36 similar similar JJ cord-005646-xhx9pzhj 155 37 edema edema NN cord-005646-xhx9pzhj 155 38 in in IN cord-005646-xhx9pzhj 155 39 both both DT cord-005646-xhx9pzhj 155 40 sides side NNS cord-005646-xhx9pzhj 155 41 . . . cord-005646-xhx9pzhj 156 1 Increased increase VBN cord-005646-xhx9pzhj 156 2 intracarotid intracarotid JJ cord-005646-xhx9pzhj 156 3 histamine histamine NN cord-005646-xhx9pzhj 156 4 levels level NNS cord-005646-xhx9pzhj 156 5 resulted result VBD cord-005646-xhx9pzhj 156 6 in in IN cord-005646-xhx9pzhj 156 7 a a DT cord-005646-xhx9pzhj 156 8 dose dose NN cord-005646-xhx9pzhj 156 9 - - HYPH cord-005646-xhx9pzhj 156 10 dependent dependent JJ cord-005646-xhx9pzhj 156 11 vasogenic vasogenic JJ cord-005646-xhx9pzhj 156 12 brain brain NN cord-005646-xhx9pzhj 156 13 edema edema NN cord-005646-xhx9pzhj 156 14 formation formation NN cord-005646-xhx9pzhj 156 15 . . . cord-005646-xhx9pzhj 157 1 Histamine histamine NN cord-005646-xhx9pzhj 157 2 might may MD cord-005646-xhx9pzhj 157 3 have have VB cord-005646-xhx9pzhj 157 4 a a DT cord-005646-xhx9pzhj 157 5 pathogenetic pathogenetic JJ cord-005646-xhx9pzhj 157 6 role role NN cord-005646-xhx9pzhj 157 7 in in IN cord-005646-xhx9pzhj 157 8 neonatal neonatal JJ cord-005646-xhx9pzhj 157 9 hypoxicischemic hypoxicischemic JJ cord-005646-xhx9pzhj 157 10 cerebral cerebral JJ cord-005646-xhx9pzhj 157 11 injuries injury NNS cord-005646-xhx9pzhj 157 12 . . . cord-005646-xhx9pzhj 158 1 Supported support VBN cord-005646-xhx9pzhj 158 2 by by IN cord-005646-xhx9pzhj 158 3 OTKA OTKA NNP cord-005646-xhx9pzhj 158 4 F-12722 f-12722 NN cord-005646-xhx9pzhj 158 5 and and CC cord-005646-xhx9pzhj 158 6 H h NN cord-005646-xhx9pzhj 158 7 - - HYPH cord-005646-xhx9pzhj 158 8 U.S,-JFNo.392 U.S,-JFNo.392 NNP cord-005646-xhx9pzhj 158 9 , , , cord-005646-xhx9pzhj 158 10 $ $ $ cord-005646-xhx9pzhj 158 11 162 162 CD cord-005646-xhx9pzhj 158 12 In in IN cord-005646-xhx9pzhj 158 13 coma coma NN cord-005646-xhx9pzhj 158 14 caused cause VBN cord-005646-xhx9pzhj 158 15 by by IN cord-005646-xhx9pzhj 158 16 traumatic traumatic JJ cord-005646-xhx9pzhj 158 17 brain brain NN cord-005646-xhx9pzhj 158 18 Jnjury Jnjury NNP cord-005646-xhx9pzhj 158 19 , , , cord-005646-xhx9pzhj 158 20 an an DT cord-005646-xhx9pzhj 158 21 indication indication NN cord-005646-xhx9pzhj 158 22 of of IN cord-005646-xhx9pzhj 158 23 the the DT cord-005646-xhx9pzhj 158 24 likely likely JJ cord-005646-xhx9pzhj 158 25 outcome outcome NN cord-005646-xhx9pzhj 158 26 is be VBZ cord-005646-xhx9pzhj 158 27 provided provide VBN cord-005646-xhx9pzhj 158 28 by by IN cord-005646-xhx9pzhj 158 29 the the DT cord-005646-xhx9pzhj 158 30 best good JJS cord-005646-xhx9pzhj 158 31 motor motor NN cord-005646-xhx9pzhj 158 32 response response NN cord-005646-xhx9pzhj 158 33 to to IN cord-005646-xhx9pzhj 158 34 pain pain NN cord-005646-xhx9pzhj 158 35 in in IN cord-005646-xhx9pzhj 158 36 the the DT cord-005646-xhx9pzhj 158 37 first first JJ cord-005646-xhx9pzhj 158 38 .$ .$ CD cord-005646-xhx9pzhj 158 39 hours hour NNS cord-005646-xhx9pzhj 158 40 after after IN cord-005646-xhx9pzhj 158 41 the the DT cord-005646-xhx9pzhj 158 42 insult insult NN cord-005646-xhx9pzhj 158 43 . . . cord-005646-xhx9pzhj 159 1 In in IN cord-005646-xhx9pzhj 159 2 a a DT cord-005646-xhx9pzhj 159 3 study study NN cord-005646-xhx9pzhj 159 4 in in IN cord-005646-xhx9pzhj 159 5 our -PRON- PRP$ cord-005646-xhx9pzhj 159 6 PICU PICU NNP cord-005646-xhx9pzhj 159 7 , , , cord-005646-xhx9pzhj 159 8 the the DT cord-005646-xhx9pzhj 159 9 proportion proportion NN cord-005646-xhx9pzhj 159 10 of of IN cord-005646-xhx9pzhj 159 11 children child NNS cord-005646-xhx9pzhj 159 12 who who WP cord-005646-xhx9pzhj 159 13 died die VBD cord-005646-xhx9pzhj 159 14 or or CC cord-005646-xhx9pzhj 159 15 had have VBD cord-005646-xhx9pzhj 159 16 a a DT cord-005646-xhx9pzhj 159 17 severe severe JJ cord-005646-xhx9pzhj 159 18 disability disability NN cord-005646-xhx9pzhj 159 19 was be VBD cord-005646-xhx9pzhj 159 20 100 100 CD cord-005646-xhx9pzhj 159 21 % % NN cord-005646-xhx9pzhj 159 22 in in IN cord-005646-xhx9pzhj 159 23 35 35 CD cord-005646-xhx9pzhj 159 24 who who WP cord-005646-xhx9pzhj 159 25 had have VBD cord-005646-xhx9pzhj 159 26 no no DT cord-005646-xhx9pzhj 159 27 response response NN cord-005646-xhx9pzhj 159 28 to to IN cord-005646-xhx9pzhj 159 29 pain pain NN cord-005646-xhx9pzhj 159 30 , , , cord-005646-xhx9pzhj 159 31 40 40 CD cord-005646-xhx9pzhj 159 32 % % NN cord-005646-xhx9pzhj 159 33 in in IN cord-005646-xhx9pzhj 159 34 47 47 CD cord-005646-xhx9pzhj 159 35 with with IN cord-005646-xhx9pzhj 159 36 an an DT cord-005646-xhx9pzhj 159 37 extensor extensor JJ cord-005646-xhx9pzhj 159 38 response response NN cord-005646-xhx9pzhj 159 39 , , , cord-005646-xhx9pzhj 159 40 14 14 CD cord-005646-xhx9pzhj 159 41 % % NN cord-005646-xhx9pzhj 159 42 in in IN cord-005646-xhx9pzhj 159 43 64 64 CD cord-005646-xhx9pzhj 159 44 with with IN cord-005646-xhx9pzhj 159 45 a a DT cord-005646-xhx9pzhj 159 46 flexor flexor NN cord-005646-xhx9pzhj 159 47 response response NN cord-005646-xhx9pzhj 159 48 , , , cord-005646-xhx9pzhj 159 49 and and CC cord-005646-xhx9pzhj 159 50 1 1 CD cord-005646-xhx9pzhj 159 51 % % NN cord-005646-xhx9pzhj 159 52 in in IN cord-005646-xhx9pzhj 159 53 61 61 CD cord-005646-xhx9pzhj 159 54 who who WP cord-005646-xhx9pzhj 159 55 localized localize VBD cord-005646-xhx9pzhj 159 56 in in IN cord-005646-xhx9pzhj 159 57 response response NN cord-005646-xhx9pzhj 159 58 to to IN cord-005646-xhx9pzhj 159 59 pain pain NN cord-005646-xhx9pzhj 159 60 . . . cord-005646-xhx9pzhj 160 1 The the DT cord-005646-xhx9pzhj 160 2 long long JJ cord-005646-xhx9pzhj 160 3 term term NN cord-005646-xhx9pzhj 160 4 outcome outcome NN cord-005646-xhx9pzhj 160 5 of of IN cord-005646-xhx9pzhj 160 6 traumatic traumatic JJ cord-005646-xhx9pzhj 160 7 brain brain NN cord-005646-xhx9pzhj 160 8 injury injury NN cord-005646-xhx9pzhj 160 9 appears appear VBZ cord-005646-xhx9pzhj 160 10 to to TO cord-005646-xhx9pzhj 160 11 be be VB cord-005646-xhx9pzhj 160 12 worse bad JJR cord-005646-xhx9pzhj 160 13 in in IN cord-005646-xhx9pzhj 160 14 children child NNS cord-005646-xhx9pzhj 160 15 < < XX cord-005646-xhx9pzhj 160 16 4 4 CD cord-005646-xhx9pzhj 160 17 years year NNS cord-005646-xhx9pzhj 160 18 old old JJ cord-005646-xhx9pzhj 160 19 . . . cord-005646-xhx9pzhj 161 1 Other other JJ cord-005646-xhx9pzhj 161 2 risk risk NN cord-005646-xhx9pzhj 161 3 factors factor NNS cord-005646-xhx9pzhj 161 4 in in IN cord-005646-xhx9pzhj 161 5 traumatic traumatic JJ cord-005646-xhx9pzhj 161 6 brain brain NN cord-005646-xhx9pzhj 161 7 injury injury NN cord-005646-xhx9pzhj 161 8 are be VBP cord-005646-xhx9pzhj 161 9 absent absent JJ cord-005646-xhx9pzhj 161 10 basal basal NN cord-005646-xhx9pzhj 161 11 cisterns cistern NNS cord-005646-xhx9pzhj 161 12 , , , cord-005646-xhx9pzhj 161 13 midline midline JJ cord-005646-xhx9pzhj 161 14 shift shift NN cord-005646-xhx9pzhj 161 15 or or CC cord-005646-xhx9pzhj 161 16 subdural subdural JJ cord-005646-xhx9pzhj 161 17 haemorrhage haemorrhage NN cord-005646-xhx9pzhj 161 18 on on IN cord-005646-xhx9pzhj 161 19 CT CT NNP cord-005646-xhx9pzhj 161 20 scan scan NN cord-005646-xhx9pzhj 161 21 ( ( -LRB- cord-005646-xhx9pzhj 161 22 or or CC cord-005646-xhx9pzhj 161 23 loss loss NN cord-005646-xhx9pzhj 161 24 of of IN cord-005646-xhx9pzhj 161 25 grey grey JJ cord-005646-xhx9pzhj 161 26 - - HYPH cord-005646-xhx9pzhj 161 27 white white JJ cord-005646-xhx9pzhj 161 28 differentiation differentiation NN cord-005646-xhx9pzhj 161 29 in in IN cord-005646-xhx9pzhj 161 30 nontraumatic nontraumatic JJ cord-005646-xhx9pzhj 161 31 injury injury NN cord-005646-xhx9pzhj 161 32 ) ) -RRB- cord-005646-xhx9pzhj 161 33 ; ; : cord-005646-xhx9pzhj 161 34 or or CC cord-005646-xhx9pzhj 161 35 an an DT cord-005646-xhx9pzhj 161 36 intracranial intracranial JJ cord-005646-xhx9pzhj 161 37 pressure pressure NN cord-005646-xhx9pzhj 161 38 > > XX cord-005646-xhx9pzhj 161 39 30 30 CD cord-005646-xhx9pzhj 161 40 mmHg mmHg NNS cord-005646-xhx9pzhj 161 41 despite despite IN cord-005646-xhx9pzhj 161 42 hyperventilation hyperventilation NN cord-005646-xhx9pzhj 161 43 , , , cord-005646-xhx9pzhj 161 44 mannitol mannitol NN cord-005646-xhx9pzhj 161 45 and and CC cord-005646-xhx9pzhj 161 46 barbiturate barbiturate NN cord-005646-xhx9pzhj 161 47 infusion infusion NN cord-005646-xhx9pzhj 161 48 . . . cord-005646-xhx9pzhj 162 1 Apart apart RB cord-005646-xhx9pzhj 162 2 from from IN cord-005646-xhx9pzhj 162 3 brain brain NN cord-005646-xhx9pzhj 162 4 death death NN cord-005646-xhx9pzhj 162 5 , , , cord-005646-xhx9pzhj 162 6 there there EX cord-005646-xhx9pzhj 162 7 are be VBP cord-005646-xhx9pzhj 162 8 two two CD cord-005646-xhx9pzhj 162 9 findings finding NNS cord-005646-xhx9pzhj 162 10 implying imply VBG cord-005646-xhx9pzhj 162 11 such such PDT cord-005646-xhx9pzhj 162 12 a a DT cord-005646-xhx9pzhj 162 13 poor poor JJ cord-005646-xhx9pzhj 162 14 prognosis prognosis NN cord-005646-xhx9pzhj 162 15 that that IN cord-005646-xhx9pzhj 162 16 consideration consideration NN cord-005646-xhx9pzhj 162 17 should should MD cord-005646-xhx9pzhj 162 18 be be VB cord-005646-xhx9pzhj 162 19 given give VBN cord-005646-xhx9pzhj 162 20 to to IN cord-005646-xhx9pzhj 162 21 stopping stop VBG cord-005646-xhx9pzhj 162 22 treatment treatment NN cord-005646-xhx9pzhj 162 23 : : : cord-005646-xhx9pzhj 162 24 first first RB cord-005646-xhx9pzhj 162 25 , , , cord-005646-xhx9pzhj 162 26 after after IN cord-005646-xhx9pzhj 162 27 traumatic traumatic JJ cord-005646-xhx9pzhj 162 28 injury injury NN cord-005646-xhx9pzhj 162 29 , , , cord-005646-xhx9pzhj 162 30 the the DT cord-005646-xhx9pzhj 162 31 absence absence NN cord-005646-xhx9pzhj 162 32 of of IN cord-005646-xhx9pzhj 162 33 any any DT cord-005646-xhx9pzhj 162 34 motor motor NN cord-005646-xhx9pzhj 162 35 response response NN cord-005646-xhx9pzhj 162 36 to to IN cord-005646-xhx9pzhj 162 37 painful painful JJ cord-005646-xhx9pzhj 162 38 stimulus stimulus NN cord-005646-xhx9pzhj 162 39 in in IN cord-005646-xhx9pzhj 162 40 the the DT cord-005646-xhx9pzhj 162 41 cranial cranial JJ cord-005646-xhx9pzhj 162 42 nerve nerve NN cord-005646-xhx9pzhj 162 43 distribution distribution NN cord-005646-xhx9pzhj 162 44 ( ( -LRB- cord-005646-xhx9pzhj 162 45 providing provide VBG cord-005646-xhx9pzhj 162 46 drug drug NN cord-005646-xhx9pzhj 162 47 effects effect NNS cord-005646-xhx9pzhj 162 48 and and CC cord-005646-xhx9pzhj 162 49 a a DT cord-005646-xhx9pzhj 162 50 post post JJ cord-005646-xhx9pzhj 162 51 - - JJ cord-005646-xhx9pzhj 162 52 ictal ictal JJ cord-005646-xhx9pzhj 162 53 state state NN cord-005646-xhx9pzhj 162 54 have have VBP cord-005646-xhx9pzhj 162 55 been be VBN cord-005646-xhx9pzhj 162 56 excluded exclude VBN cord-005646-xhx9pzhj 162 57 ) ) -RRB- cord-005646-xhx9pzhj 162 58 ; ; : cord-005646-xhx9pzhj 162 59 and and CC cord-005646-xhx9pzhj 162 60 second second RB cord-005646-xhx9pzhj 162 61 , , , cord-005646-xhx9pzhj 162 62 in in IN cord-005646-xhx9pzhj 162 63 acute acute JJ cord-005646-xhx9pzhj 162 64 brain brain NN cord-005646-xhx9pzhj 162 65 injury injury NN cord-005646-xhx9pzhj 162 66 from from IN cord-005646-xhx9pzhj 162 67 trauma trauma NN cord-005646-xhx9pzhj 162 68 , , , cord-005646-xhx9pzhj 162 69 infection infection NN cord-005646-xhx9pzhj 162 70 , , , cord-005646-xhx9pzhj 162 71 hypoxia hypoxia NN cord-005646-xhx9pzhj 162 72 , , , cord-005646-xhx9pzhj 162 73 or or CC cord-005646-xhx9pzhj 162 74 ischaemia ischaemia NN cord-005646-xhx9pzhj 162 75 , , , cord-005646-xhx9pzhj 162 76 the the DT cord-005646-xhx9pzhj 162 77 b{lateral b{lateral JJ cord-005646-xhx9pzhj 162 78 absence absence NN cord-005646-xhx9pzhj 162 79 of of IN cord-005646-xhx9pzhj 162 80 short short JJ cord-005646-xhx9pzhj 162 81 - - HYPH cord-005646-xhx9pzhj 162 82 latency latency NN cord-005646-xhx9pzhj 162 83 somatosensory somatosensory NN cord-005646-xhx9pzhj 162 84 evoked evoke VBN cord-005646-xhx9pzhj 162 85 potentials potential NNS cord-005646-xhx9pzhj 162 86 ( ( -LRB- cord-005646-xhx9pzhj 162 87 providing provide VBG cord-005646-xhx9pzhj 162 88 brain brain NN cord-005646-xhx9pzhj 162 89 stem stem NN cord-005646-xhx9pzhj 162 90 haemorrhage haemorrhage NN cord-005646-xhx9pzhj 162 91 , , , cord-005646-xhx9pzhj 162 92 subdural subdural JJ cord-005646-xhx9pzhj 162 93 and and CC cord-005646-xhx9pzhj 162 94 extradural extradural JJ cord-005646-xhx9pzhj 162 95 effusions effusion NNS cord-005646-xhx9pzhj 162 96 , , , cord-005646-xhx9pzhj 162 97 and and CC cord-005646-xhx9pzhj 162 98 decompressive decompressive NNP cord-005646-xhx9pzhj 162 99 craniectomy craniectomy NNP cord-005646-xhx9pzhj 162 100 have have VBP cord-005646-xhx9pzhj 162 101 been be VBN cord-005646-xhx9pzhj 162 102 excluded exclude VBN cord-005646-xhx9pzhj 162 103 ) ) -RRB- cord-005646-xhx9pzhj 162 104 . . . cord-005646-xhx9pzhj 163 1 In in IN cord-005646-xhx9pzhj 163 2 children child NNS cord-005646-xhx9pzhj 163 3 over over IN cord-005646-xhx9pzhj 163 4 2 2 CD cord-005646-xhx9pzhj 163 5 months month NNS cord-005646-xhx9pzhj 163 6 of of IN cord-005646-xhx9pzhj 163 7 age age NN cord-005646-xhx9pzhj 163 8 , , , cord-005646-xhx9pzhj 163 9 recovery recovery NN cord-005646-xhx9pzhj 163 10 from from IN cord-005646-xhx9pzhj 163 11 prolonged prolonged JJ cord-005646-xhx9pzhj 163 12 coma coma NN cord-005646-xhx9pzhj 163 13 or or CC cord-005646-xhx9pzhj 163 14 a a DT cord-005646-xhx9pzhj 163 15 vegetative vegetative JJ cord-005646-xhx9pzhj 163 16 state state NN cord-005646-xhx9pzhj 163 17 is be VBZ cord-005646-xhx9pzhj 163 18 exceedingly exceedingly RB cord-005646-xhx9pzhj 163 19 rare rare JJ cord-005646-xhx9pzhj 163 20 when when WRB cord-005646-xhx9pzhj 163 21 more more JJR cord-005646-xhx9pzhj 163 22 than than IN cord-005646-xhx9pzhj 163 23 12 12 CD cord-005646-xhx9pzhj 163 24 months month NNS cord-005646-xhx9pzhj 163 25 have have VBP cord-005646-xhx9pzhj 163 26 elapsed elapse VBN cord-005646-xhx9pzhj 163 27 after after IN cord-005646-xhx9pzhj 163 28 traumatic traumatic JJ cord-005646-xhx9pzhj 163 29 brain brain NN cord-005646-xhx9pzhj 163 30 injury injury NN cord-005646-xhx9pzhj 163 31 , , , cord-005646-xhx9pzhj 163 32 and and CC cord-005646-xhx9pzhj 163 33 when when WRB cord-005646-xhx9pzhj 163 34 more more JJR cord-005646-xhx9pzhj 163 35 than than IN cord-005646-xhx9pzhj 163 36 3 3 CD cord-005646-xhx9pzhj 163 37 months month NNS cord-005646-xhx9pzhj 163 38 have have VBP cord-005646-xhx9pzhj 163 39 elapsed elapse VBN cord-005646-xhx9pzhj 163 40 after after IN cord-005646-xhx9pzhj 163 41 nontraumatic nontraumatic JJ cord-005646-xhx9pzhj 163 42 injury injury NN cord-005646-xhx9pzhj 163 43 . . . cord-005646-xhx9pzhj 164 1 Overproduction overproduction NN cord-005646-xhx9pzhj 164 2 of of IN cord-005646-xhx9pzhj 164 3 nitric nitric NN cord-005646-xhx9pzhj 164 4 oxide oxide NN cord-005646-xhx9pzhj 164 5 ( ( -LRB- cord-005646-xhx9pzhj 164 6 NO no UH cord-005646-xhx9pzhj 164 7 ) ) -RRB- cord-005646-xhx9pzhj 164 8 via via IN cord-005646-xhx9pzhj 164 9 an an DT cord-005646-xhx9pzhj 164 10 inducible inducible JJ cord-005646-xhx9pzhj 164 11 isoform isoform NN cord-005646-xhx9pzhj 164 12 of of IN cord-005646-xhx9pzhj 164 13 " " `` cord-005646-xhx9pzhj 164 14 NO NO NNP cord-005646-xhx9pzhj 164 15 synthasc synthasc NNP cord-005646-xhx9pzhj 164 16 ( ( -LRB- cord-005646-xhx9pzhj 164 17 iNOS inos NN cord-005646-xhx9pzhj 164 18 ) ) -RRB- cord-005646-xhx9pzhj 164 19 produces produce VBZ cord-005646-xhx9pzhj 164 20 profound profound JJ cord-005646-xhx9pzhj 164 21 vasodilatation vasodilatation NN cord-005646-xhx9pzhj 164 22 in in IN cord-005646-xhx9pzhj 164 23 adult adult NN cord-005646-xhx9pzhj 164 24 septic septic JJ cord-005646-xhx9pzhj 164 25 shock shock NN cord-005646-xhx9pzhj 164 26 . . . cord-005646-xhx9pzhj 165 1 High high JJ cord-005646-xhx9pzhj 165 2 nitrate nitrate NN cord-005646-xhx9pzhj 165 3 levels level NNS cord-005646-xhx9pzhj 165 4 have have VBP cord-005646-xhx9pzhj 165 5 been be VBN cord-005646-xhx9pzhj 165 6 reported report VBN cord-005646-xhx9pzhj 165 7 in in IN cord-005646-xhx9pzhj 165 8 hypotensive hypotensive JJ cord-005646-xhx9pzhj 165 9 children child NNS cord-005646-xhx9pzhj 165 10 with with IN cord-005646-xhx9pzhj 165 11 sepsis sepsis NN cord-005646-xhx9pzhj 165 12 syndrome syndrome NN cord-005646-xhx9pzhj 165 13 ] ] -RRB- cord-005646-xhx9pzhj 165 14 . . . cord-005646-xhx9pzhj 166 1 Cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 166 2 collapse collapse NN cord-005646-xhx9pzhj 166 3 is be VBZ cord-005646-xhx9pzhj 166 4 a a DT cord-005646-xhx9pzhj 166 5 prominent prominent JJ cord-005646-xhx9pzhj 166 6 feature feature NN cord-005646-xhx9pzhj 166 7 of of IN cord-005646-xhx9pzhj 166 8 severe severe JJ cord-005646-xhx9pzhj 166 9 meningocoecaI meningocoecaI NNP cord-005646-xhx9pzhj 166 10 disease disease NN cord-005646-xhx9pzhj 166 11 ( ( -LRB- cord-005646-xhx9pzhj 166 12 MCD MCD NNP cord-005646-xhx9pzhj 166 13 ) ) -RRB- cord-005646-xhx9pzhj 166 14 . . . cord-005646-xhx9pzhj 167 1 However however RB cord-005646-xhx9pzhj 167 2 , , , cord-005646-xhx9pzhj 167 3 systemic systemic JJ cord-005646-xhx9pzhj 167 4 vascular vascular JJ cord-005646-xhx9pzhj 167 5 resistance resistance NN cord-005646-xhx9pzhj 167 6 ( ( -LRB- cord-005646-xhx9pzhj 167 7 SVR SVR NNP cord-005646-xhx9pzhj 167 8 ) ) -RRB- cord-005646-xhx9pzhj 167 9 was be VBD cord-005646-xhx9pzhj 167 10 slightly slightly RB cord-005646-xhx9pzhj 167 11 higher high JJR cord-005646-xhx9pzhj 167 12 in in IN cord-005646-xhx9pzhj 167 13 a a DT cord-005646-xhx9pzhj 167 14 group group NN cord-005646-xhx9pzhj 167 15 of of IN cord-005646-xhx9pzhj 167 16 non non NNS cord-005646-xhx9pzhj 167 17 - - NNS cord-005646-xhx9pzhj 167 18 survivors survivor NNS cord-005646-xhx9pzhj 167 19 ~ ~ NFP cord-005646-xhx9pzhj 167 20 and and CC cord-005646-xhx9pzhj 167 21 the the DT cord-005646-xhx9pzhj 167 22 rote rote NN cord-005646-xhx9pzhj 167 23 of of IN cord-005646-xhx9pzhj 167 24 NO no DT cord-005646-xhx9pzhj 167 25 in in IN cord-005646-xhx9pzhj 167 26 IvICD IvICD NNP cord-005646-xhx9pzhj 167 27 remains remain VBZ cord-005646-xhx9pzhj 167 28 unclear unclear JJ cord-005646-xhx9pzhj 167 29 . . . cord-005646-xhx9pzhj 168 1 Children child NNS cord-005646-xhx9pzhj 168 2 with with IN cord-005646-xhx9pzhj 168 3 a a DT cord-005646-xhx9pzhj 168 4 presumptive presumptive JJ cord-005646-xhx9pzhj 168 5 diagnosis diagnosis NN cord-005646-xhx9pzhj 168 6 of of IN cord-005646-xhx9pzhj 168 7 MCD MCD NNP cord-005646-xhx9pzhj 168 8 were be VBD cord-005646-xhx9pzhj 168 9 enrolled enrol VBN cord-005646-xhx9pzhj 168 10 . . . cord-005646-xhx9pzhj 169 1 Parental parental JJ cord-005646-xhx9pzhj 169 2 consent consent NN cord-005646-xhx9pzhj 169 3 was be VBD cord-005646-xhx9pzhj 169 4 obtained obtain VBN cord-005646-xhx9pzhj 169 5 . . . cord-005646-xhx9pzhj 170 1 Blood blood NN cord-005646-xhx9pzhj 170 2 was be VBD cord-005646-xhx9pzhj 170 3 drawn draw VBN cord-005646-xhx9pzhj 170 4 on on IN cord-005646-xhx9pzhj 170 5 admission admission NN cord-005646-xhx9pzhj 170 6 and and CC cord-005646-xhx9pzhj 170 7 12hrly 12hrly RB cord-005646-xhx9pzhj 170 8 thereafter thereafter RB cord-005646-xhx9pzhj 170 9 . . . cord-005646-xhx9pzhj 171 1 Plasma plasma NN cord-005646-xhx9pzhj 171 2 was be VBD cord-005646-xhx9pzhj 171 3 separated separate VBN cord-005646-xhx9pzhj 171 4 immediately immediately RB cord-005646-xhx9pzhj 171 5 and and CC cord-005646-xhx9pzhj 171 6 stored store VBN cord-005646-xhx9pzhj 171 7 at at IN cord-005646-xhx9pzhj 171 8 -80 -80 NNP cord-005646-xhx9pzhj 171 9 ° ° NN cord-005646-xhx9pzhj 171 10 C C NNP cord-005646-xhx9pzhj 171 11 . . . cord-005646-xhx9pzhj 172 1 The the DT cord-005646-xhx9pzhj 172 2 final final JJ cord-005646-xhx9pzhj 172 3 concentrations concentration NNS cord-005646-xhx9pzhj 172 4 reported report VBD cord-005646-xhx9pzhj 172 5 represent represent VBP cord-005646-xhx9pzhj 172 6 the the DT cord-005646-xhx9pzhj 172 7 product product NN cord-005646-xhx9pzhj 172 8 of of IN cord-005646-xhx9pzhj 172 9 nitrite nitrite NN cord-005646-xhx9pzhj 172 10 and and CC cord-005646-xhx9pzhj 172 11 nitrate nitrate NN cord-005646-xhx9pzhj 172 12 ( ( -LRB- cord-005646-xhx9pzhj 172 13 NOx NOx NNP cord-005646-xhx9pzhj 172 14 ) ) -RRB- cord-005646-xhx9pzhj 172 15 . . . cord-005646-xhx9pzhj 173 1 NOx NOx NNP cord-005646-xhx9pzhj 173 2 was be VBD cord-005646-xhx9pzhj 173 3 measured measure VBN cord-005646-xhx9pzhj 173 4 spectrophotometrically spectrophotometrically RB cord-005646-xhx9pzhj 173 5 using use VBG cord-005646-xhx9pzhj 173 6 the the DT cord-005646-xhx9pzhj 173 7 Greiss Greiss NNP cord-005646-xhx9pzhj 173 8 reaction reaction NN cord-005646-xhx9pzhj 173 9 . . . cord-005646-xhx9pzhj 174 1 21 21 CD cord-005646-xhx9pzhj 174 2 children child NNS cord-005646-xhx9pzhj 174 3 were be VBD cord-005646-xhx9pzhj 174 4 studied study VBN cord-005646-xhx9pzhj 174 5 ( ( -LRB- cord-005646-xhx9pzhj 174 6 median median JJ cord-005646-xhx9pzhj 174 7 age age NN cord-005646-xhx9pzhj 174 8 ( ( -LRB- cord-005646-xhx9pzhj 174 9 range range NN cord-005646-xhx9pzhj 174 10 ) ) -RRB- cord-005646-xhx9pzhj 174 11 ; ; : cord-005646-xhx9pzhj 174 12 27 27 CD cord-005646-xhx9pzhj 174 13 m m NN cord-005646-xhx9pzhj 174 14 ( ( -LRB- cord-005646-xhx9pzhj 174 15 5 5 CD cord-005646-xhx9pzhj 174 16 - - SYM cord-005646-xhx9pzhj 174 17 203 203 CD cord-005646-xhx9pzhj 174 18 ) ) -RRB- cord-005646-xhx9pzhj 174 19 ) ) -RRB- cord-005646-xhx9pzhj 174 20 . . . cord-005646-xhx9pzhj 175 1 The the DT cord-005646-xhx9pzhj 175 2 diagnosis diagnosis NN cord-005646-xhx9pzhj 175 3 of of IN cord-005646-xhx9pzhj 175 4 MCD MCD NNP cord-005646-xhx9pzhj 175 5 was be VBD cord-005646-xhx9pzhj 175 6 confirmed confirm VBN cord-005646-xhx9pzhj 175 7 in in IN cord-005646-xhx9pzhj 175 8 18 18 CD cord-005646-xhx9pzhj 175 9 children child NNS cord-005646-xhx9pzhj 175 10 , , , cord-005646-xhx9pzhj 175 11 12 12 CD cord-005646-xhx9pzhj 175 12 of of IN cord-005646-xhx9pzhj 175 13 whom whom WP cord-005646-xhx9pzhj 175 14 had have VBD cord-005646-xhx9pzhj 175 15 a a DT cord-005646-xhx9pzhj 175 16 Glasgow Glasgow NNP cord-005646-xhx9pzhj 175 17 Meningococcal Meningococcal NNP cord-005646-xhx9pzhj 175 18 Score score NN cord-005646-xhx9pzhj 175 19 ( ( -LRB- cord-005646-xhx9pzhj 175 20 GMS GMS NNP cord-005646-xhx9pzhj 175 21 ) ) -RRB- cord-005646-xhx9pzhj 175 22 of of IN cord-005646-xhx9pzhj 175 23 " " `` cord-005646-xhx9pzhj 175 24 ~8 ~8 CD cord-005646-xhx9pzhj 175 25 . . . cord-005646-xhx9pzhj 176 1 In in IN cord-005646-xhx9pzhj 176 2 this this DT cord-005646-xhx9pzhj 176 3 group group NN cord-005646-xhx9pzhj 176 4 with with IN cord-005646-xhx9pzhj 176 5 severe severe JJ cord-005646-xhx9pzhj 176 6 MCD MCD NNP cord-005646-xhx9pzhj 176 7 there there EX cord-005646-xhx9pzhj 176 8 were be VBD cord-005646-xhx9pzhj 176 9 3 3 CD cord-005646-xhx9pzhj 176 10 deaths death NNS cord-005646-xhx9pzhj 176 11 . . . cord-005646-xhx9pzhj 177 1 Peak Peak NNP cord-005646-xhx9pzhj 177 2 NOx NOx NNP cord-005646-xhx9pzhj 177 3 was be VBD cord-005646-xhx9pzhj 177 4 significantly significantly RB cord-005646-xhx9pzhj 177 5 higher high JJR cord-005646-xhx9pzhj 177 6 ( ( -LRB- cord-005646-xhx9pzhj 177 7 , , , cord-005646-xhx9pzhj 177 8 .54(27 .54(27 NNP cord-005646-xhx9pzhj 177 9 - - HYPH cord-005646-xhx9pzhj 177 10 78 78 CD cord-005646-xhx9pzhj 177 11 ) ) -RRB- cord-005646-xhx9pzhj 177 12 vs vs IN cord-005646-xhx9pzhj 177 13 96(50 96(50 CD cord-005646-xhx9pzhj 177 14 - - HYPH cord-005646-xhx9pzhj 177 15 363)nmol 363)nmol CD cord-005646-xhx9pzhj 177 16 / / SYM cord-005646-xhx9pzhj 177 17 ml ml NN cord-005646-xhx9pzhj 177 18 , , , cord-005646-xhx9pzhj 177 19 median median NN cord-005646-xhx9pzhj 177 20 ) ) -RRB- cord-005646-xhx9pzhj 177 21 and and CC cord-005646-xhx9pzhj 177 22 systolic systolic JJ cord-005646-xhx9pzhj 177 23 btood btood NNP cord-005646-xhx9pzhj 177 24 pressure pressure NN cord-005646-xhx9pzhj 177 25 was be VBD cord-005646-xhx9pzhj 177 26 significantly significantly RB cord-005646-xhx9pzhj 177 27 lower low JJR cord-005646-xhx9pzhj 177 28 in in IN cord-005646-xhx9pzhj 177 29 children child NNS cord-005646-xhx9pzhj 177 30 with with IN cord-005646-xhx9pzhj 177 31 severe severe JJ cord-005646-xhx9pzhj 177 32 MCD mcd NN cord-005646-xhx9pzhj 177 33 than than IN cord-005646-xhx9pzhj 177 34 mild mild JJ cord-005646-xhx9pzhj 177 35 MCD MCD NNP cord-005646-xhx9pzhj 177 36 ( ( -LRB- cord-005646-xhx9pzhj 177 37 p<0.05 p<0.05 NNP cord-005646-xhx9pzhj 177 38 . . . cord-005646-xhx9pzhj 178 1 Wilcoxon Wilcoxon NNP cord-005646-xhx9pzhj 178 2 rank rank NN cord-005646-xhx9pzhj 178 3 test test NN cord-005646-xhx9pzhj 178 4 ) ) -RRB- cord-005646-xhx9pzhj 178 5 . . . cord-005646-xhx9pzhj 179 1 There there EX cord-005646-xhx9pzhj 179 2 was be VBD cord-005646-xhx9pzhj 179 3 a a DT cord-005646-xhx9pzhj 179 4 significant significant JJ cord-005646-xhx9pzhj 179 5 correlation correlation NN cord-005646-xhx9pzhj 179 6 between between IN cord-005646-xhx9pzhj 179 7 peak peak NN cord-005646-xhx9pzhj 179 8 NOx NOx NNS cord-005646-xhx9pzhj 179 9 and and CC cord-005646-xhx9pzhj 179 10 GMS GMS NNP cord-005646-xhx9pzhj 180 1 ( ( -LRB- cord-005646-xhx9pzhj 180 2 Spearman Spearman NNP cord-005646-xhx9pzhj 180 3 's 's POS cord-005646-xhx9pzhj 180 4 rank rank NN cord-005646-xhx9pzhj 180 5 correlation correlation NN cord-005646-xhx9pzhj 180 6 r=0.6 r=0.6 NNP cord-005646-xhx9pzhj 180 7 ( ( -LRB- cord-005646-xhx9pzhj 180 8 p=0.01 p=0.01 NNP cord-005646-xhx9pzhj 180 9 ) ) -RRB- cord-005646-xhx9pzhj 180 10 ) ) -RRB- cord-005646-xhx9pzhj 180 11 and and CC cord-005646-xhx9pzhj 180 12 PRISM PRISM NNP cord-005646-xhx9pzhj 180 13 ( ( -LRB- cord-005646-xhx9pzhj 180 14 r=0.6 r=0.6 NNP cord-005646-xhx9pzhj 180 15 ( ( -LRB- cord-005646-xhx9pzhj 180 16 p:0.01 p:0.01 NNP cord-005646-xhx9pzhj 180 17 ) ) -RRB- cord-005646-xhx9pzhj 180 18 ) ) -RRB- cord-005646-xhx9pzhj 180 19 . . . cord-005646-xhx9pzhj 181 1 NOx nox NN cord-005646-xhx9pzhj 181 2 production production NN cord-005646-xhx9pzhj 181 3 from from IN cord-005646-xhx9pzhj 181 4 adm.ission adm.ission NNP cord-005646-xhx9pzhj 181 5 onwards onwards RB cord-005646-xhx9pzhj 181 6 was be VBD cord-005646-xhx9pzhj 181 7 also also RB cord-005646-xhx9pzhj 181 8 higher high JJR cord-005646-xhx9pzhj 181 9 in in IN cord-005646-xhx9pzhj 181 10 the the DT cord-005646-xhx9pzhj 181 11 severe severe JJ cord-005646-xhx9pzhj 181 12 MCD MCD NNP cord-005646-xhx9pzhj 181 13 group group NN cord-005646-xhx9pzhj 181 14 ( ( -LRB- cord-005646-xhx9pzhj 181 15 p:0.002 p:0.002 NNP cord-005646-xhx9pzhj 181 16 , , , cord-005646-xhx9pzhj 181 17 Kmskal Kmskal NNP cord-005646-xhx9pzhj 181 18 ~Wallis ~Wallis NFP cord-005646-xhx9pzhj 181 19 ) ) -RRB- cord-005646-xhx9pzhj 181 20 . . . cord-005646-xhx9pzhj 182 1 We -PRON- PRP cord-005646-xhx9pzhj 182 2 have have VBP cord-005646-xhx9pzhj 182 3 demonstrated demonstrate VBN cord-005646-xhx9pzhj 182 4 that that IN cord-005646-xhx9pzhj 182 5 plasma plasma NN cord-005646-xhx9pzhj 182 6 NOx nox NN cord-005646-xhx9pzhj 182 7 levels level NNS cord-005646-xhx9pzhj 182 8 are be VBP cord-005646-xhx9pzhj 182 9 elevated elevate VBN cord-005646-xhx9pzhj 182 10 in in IN cord-005646-xhx9pzhj 182 11 children child NNS cord-005646-xhx9pzhj 182 12 with with IN cord-005646-xhx9pzhj 182 13 MCD MCD NNP cord-005646-xhx9pzhj 182 14 , , , cord-005646-xhx9pzhj 182 15 correlate correlate VBP cord-005646-xhx9pzhj 182 16 directly directly RB cord-005646-xhx9pzhj 182 17 with with IN cord-005646-xhx9pzhj 182 18 the the DT cord-005646-xhx9pzhj 182 19 severit severit NNP cord-005646-xhx9pzhj 182 20 3 3 NNP cord-005646-xhx9pzhj 182 21 ' ' '' cord-005646-xhx9pzhj 182 22 of of IN cord-005646-xhx9pzhj 182 23 disease disease NN cord-005646-xhx9pzhj 182 24 and and CC cord-005646-xhx9pzhj 182 25 are be VBP cord-005646-xhx9pzhj 182 26 inversly inversly RB cord-005646-xhx9pzhj 182 27 related relate VBN cord-005646-xhx9pzhj 182 28 to to IN cord-005646-xhx9pzhj 182 29 systolic systolic JJ cord-005646-xhx9pzhj 182 30 blood blood NN cord-005646-xhx9pzhj 182 31 presssure presssure NN cord-005646-xhx9pzhj 182 32 . . . cord-005646-xhx9pzhj 183 1 Similar similar JJ cord-005646-xhx9pzhj 183 2 to to IN cord-005646-xhx9pzhj 183 3 hypotensive hypotensive JJ cord-005646-xhx9pzhj 183 4 septic septic JJ cord-005646-xhx9pzhj 183 5 syndrome syndrome NN cord-005646-xhx9pzhj 183 6 , , , cord-005646-xhx9pzhj 183 7 MCD MCD NNP cord-005646-xhx9pzhj 183 8 appears appear VBZ cord-005646-xhx9pzhj 183 9 to to TO cord-005646-xhx9pzhj 183 10 be be VB cord-005646-xhx9pzhj 183 11 associated associate VBN cord-005646-xhx9pzhj 183 12 with with IN cord-005646-xhx9pzhj 183 13 an an DT cord-005646-xhx9pzhj 183 14 up up JJ cord-005646-xhx9pzhj 183 15 - - HYPH cord-005646-xhx9pzhj 183 16 regulation regulation NN cord-005646-xhx9pzhj 183 17 of of IN cord-005646-xhx9pzhj 183 18 the the DT cord-005646-xhx9pzhj 183 19 L l NN cord-005646-xhx9pzhj 183 20 - - HYPH cord-005646-xhx9pzhj 183 21 arginine arginine NN cord-005646-xhx9pzhj 183 22 - - HYPH cord-005646-xhx9pzhj 183 23 NO no NN cord-005646-xhx9pzhj 183 24 pathway pathway NN cord-005646-xhx9pzhj 183 25 .. .. . cord-005646-xhx9pzhj 184 1 Non Non NNS cord-005646-xhx9pzhj 184 2 - - NNS cord-005646-xhx9pzhj 184 3 survivors survivor NNS cord-005646-xhx9pzhj 184 4 with with IN cord-005646-xhx9pzhj 184 5 MCD MCD NNP cord-005646-xhx9pzhj 184 6 have have VBP cord-005646-xhx9pzhj 184 7 higher high JJR cord-005646-xhx9pzhj 184 8 SVRs svr NNS cord-005646-xhx9pzhj 184 9 and and CC cord-005646-xhx9pzhj 184 10 may may MD cord-005646-xhx9pzhj 184 11 be be VB cord-005646-xhx9pzhj 184 12 relatively relatively RB cord-005646-xhx9pzhj 184 13 hypovolaemic hypovolaemic JJ cord-005646-xhx9pzhj 184 14 . . . cord-005646-xhx9pzhj 185 1 In in IN cord-005646-xhx9pzhj 185 2 our -PRON- PRP$ cord-005646-xhx9pzhj 185 3 group group NN cord-005646-xhx9pzhj 185 4 of of IN cord-005646-xhx9pzhj 185 5 severe severe JJ cord-005646-xhx9pzhj 185 6 MCD MCD NNP cord-005646-xhx9pzhj 185 7 there there EX cord-005646-xhx9pzhj 185 8 was be VBD cord-005646-xhx9pzhj 185 9 a a DT cord-005646-xhx9pzhj 185 10 significantly significantly RB cord-005646-xhx9pzhj 185 11 lower low JJR cord-005646-xhx9pzhj 185 12 systolic systolic JJ cord-005646-xhx9pzhj 185 13 pressure pressure NN cord-005646-xhx9pzhj 185 14 and and CC cord-005646-xhx9pzhj 185 15 increased increase VBD cord-005646-xhx9pzhj 185 16 NO no DT cord-005646-xhx9pzhj 185 17 formation formation NN cord-005646-xhx9pzhj 185 18 . . . cord-005646-xhx9pzhj 186 1 Excess excess JJ cord-005646-xhx9pzhj 186 2 iNOS inos JJ cord-005646-xhx9pzhj 186 3 expression expression NN cord-005646-xhx9pzhj 186 4 at at IN cord-005646-xhx9pzhj 186 5 different different JJ cord-005646-xhx9pzhj 186 6 stages stage NNS cord-005646-xhx9pzhj 186 7 in in IN cord-005646-xhx9pzhj 186 8 MCD MCD NNP cord-005646-xhx9pzhj 186 9 may may MD cord-005646-xhx9pzhj 186 10 contribute contribute VB cord-005646-xhx9pzhj 186 11 to to IN cord-005646-xhx9pzhj 186 12 the the DT cord-005646-xhx9pzhj 186 13 pathology pathology NN cord-005646-xhx9pzhj 186 14 of of IN cord-005646-xhx9pzhj 186 15 the the DT cord-005646-xhx9pzhj 186 16 disease disease NN cord-005646-xhx9pzhj 186 17 . . . cord-005646-xhx9pzhj 187 1 The the DT cord-005646-xhx9pzhj 187 2 identification identification NN cord-005646-xhx9pzhj 187 3 of of IN cord-005646-xhx9pzhj 187 4 agents agent NNS cord-005646-xhx9pzhj 187 5 which which WDT cord-005646-xhx9pzhj 187 6 can can MD cord-005646-xhx9pzhj 187 7 boost boost VB cord-005646-xhx9pzhj 187 8 and/or and/or CC cord-005646-xhx9pzhj 187 9 inhibit inhibit VB cord-005646-xhx9pzhj 187 10 NO no DT cord-005646-xhx9pzhj 187 11 reiease reiease NN cord-005646-xhx9pzhj 187 12 may may MD cord-005646-xhx9pzhj 187 13 therefore therefore RB cord-005646-xhx9pzhj 187 14 represent represent VB cord-005646-xhx9pzhj 187 15 different different JJ cord-005646-xhx9pzhj 187 16 treatment treatment NN cord-005646-xhx9pzhj 187 17 strategies strategy NNS cord-005646-xhx9pzhj 187 18 for for IN cord-005646-xhx9pzhj 187 19 MCD MCD NNP cord-005646-xhx9pzhj 187 20 . . . cord-005646-xhx9pzhj 188 1 U. U. NNP cord-005646-xhx9pzhj 188 2 Merz Merz NNP cord-005646-xhx9pzhj 188 3 , , , cord-005646-xhx9pzhj 189 1 Th th JJ cord-005646-xhx9pzhj 189 2 . . . cord-005646-xhx9pzhj 190 1 Peschgens Peschgens NNP cord-005646-xhx9pzhj 190 2 , , , cord-005646-xhx9pzhj 190 3 G. G. NNP cord-005646-xhx9pzhj 190 4 Kusenbach Kusenbach NNP cord-005646-xhx9pzhj 190 5 , , , cord-005646-xhx9pzhj 190 6 M. M. NNP cord-005646-xhx9pzhj 190 7 B6hle B6hle NNP cord-005646-xhx9pzhj 190 8 , , , cord-005646-xhx9pzhj 190 9 H. H. NNP cord-005646-xhx9pzhj 190 10 H6rnchen H6rnchen NNP cord-005646-xhx9pzhj 191 1 In in IN cord-005646-xhx9pzhj 191 2 this this DT cord-005646-xhx9pzhj 191 3 controlled control VBN cord-005646-xhx9pzhj 191 4 , , , cord-005646-xhx9pzhj 191 5 prospective prospective JJ cord-005646-xhx9pzhj 191 6 study study NN cord-005646-xhx9pzhj 191 7 30 30 CD cord-005646-xhx9pzhj 191 8 ventilated ventilate VBD cord-005646-xhx9pzhj 191 9 premature premature JJ cord-005646-xhx9pzhj 191 10 infants infant NNS cord-005646-xhx9pzhj 191 11 with with IN cord-005646-xhx9pzhj 191 12 a a DT cord-005646-xhx9pzhj 191 13 birth birth NN cord-005646-xhx9pzhj 191 14 weight weight NN cord-005646-xhx9pzhj 192 1 < < NNP cord-005646-xhx9pzhj 192 2 1250 1250 CD cord-005646-xhx9pzhj 192 3 g g NNP cord-005646-xhx9pzhj 192 4 were be VBD cord-005646-xhx9pzhj 192 5 randomized randomize VBN cord-005646-xhx9pzhj 192 6 to to TO cord-005646-xhx9pzhj 192 7 receive receive VB cord-005646-xhx9pzhj 192 8 treatment treatment NN cord-005646-xhx9pzhj 192 9 with with IN cord-005646-xhx9pzhj 192 10 dexamethasone dexamethasone NN cord-005646-xhx9pzhj 192 11 ( ( -LRB- cord-005646-xhx9pzhj 192 12 DEX DEX NNP cord-005646-xhx9pzhj 192 13 ) ) -RRB- cord-005646-xhx9pzhj 192 14 either either CC cord-005646-xhx9pzhj 192 15 on on IN cord-005646-xhx9pzhj 192 16 day day NN cord-005646-xhx9pzhj 192 17 7 7 CD cord-005646-xhx9pzhj 192 18 of of IN cord-005646-xhx9pzhj 192 19 life life NN cord-005646-xhx9pzhj 192 20 or or CC cord-005646-xhx9pzhj 192 21 on on IN cord-005646-xhx9pzhj 192 22 day day NN cord-005646-xhx9pzhj 192 23 14 14 CD cord-005646-xhx9pzhj 192 24 of of IN cord-005646-xhx9pzhj 192 25 life life NN cord-005646-xhx9pzhj 192 26 . . . cord-005646-xhx9pzhj 193 1 DEX DEX NNP cord-005646-xhx9pzhj 193 2 was be VBD cord-005646-xhx9pzhj 193 3 given give VBN cord-005646-xhx9pzhj 193 4 over over IN cord-005646-xhx9pzhj 193 5 16 16 CD cord-005646-xhx9pzhj 193 6 days day NNS cord-005646-xhx9pzhj 193 7 tapering taper VBG cord-005646-xhx9pzhj 193 8 from from IN cord-005646-xhx9pzhj 193 9 0.5 0.5 CD cord-005646-xhx9pzhj 193 10 mg mg NNP cord-005646-xhx9pzhj 193 11 / / SYM cord-005646-xhx9pzhj 193 12 kg kg NNP cord-005646-xhx9pzhj 193 13 / / SYM cord-005646-xhx9pzhj 193 14 day day NN cord-005646-xhx9pzhj 193 15 to to IN cord-005646-xhx9pzhj 193 16 0.1 0.1 CD cord-005646-xhx9pzhj 193 17 mg mg NNP cord-005646-xhx9pzhj 193 18 / / SYM cord-005646-xhx9pzhj 193 19 kg kg NNP cord-005646-xhx9pzhj 193 20 / / SYM cord-005646-xhx9pzhj 193 21 day day NN cord-005646-xhx9pzhj 193 22 . . . cord-005646-xhx9pzhj 194 1 The the DT cord-005646-xhx9pzhj 194 2 infants infant NNS cord-005646-xhx9pzhj 194 3 treated treat VBN cord-005646-xhx9pzhj 194 4 with with IN cord-005646-xhx9pzhj 194 5 DEX DEX NNP cord-005646-xhx9pzhj 194 6 on on IN cord-005646-xhx9pzhj 194 7 day day NN cord-005646-xhx9pzhj 194 8 7 7 CD cord-005646-xhx9pzhj 194 9 of of IN cord-005646-xhx9pzhj 194 10 life life NN cord-005646-xhx9pzhj 194 11 could could MD cord-005646-xhx9pzhj 194 12 be be VB cord-005646-xhx9pzhj 194 13 weaned wean VBN cord-005646-xhx9pzhj 194 14 earlier early RBR cord-005646-xhx9pzhj 194 15 from from IN cord-005646-xhx9pzhj 194 16 the the DT cord-005646-xhx9pzhj 194 17 ventilator ventilator NN cord-005646-xhx9pzhj 194 18 -in -in IN cord-005646-xhx9pzhj 194 19 median median NN cord-005646-xhx9pzhj 194 20 after after IN cord-005646-xhx9pzhj 194 21 14 14 CD cord-005646-xhx9pzhj 194 22 days day NNS cord-005646-xhx9pzhj 194 23 ( ( -LRB- cord-005646-xhx9pzhj 194 24 range range VB cord-005646-xhx9pzhj 194 25 10 10 CD cord-005646-xhx9pzhj 194 26 -34 -34 CD cord-005646-xhx9pzhj 194 27 ) ) -RRB- cord-005646-xhx9pzhj 194 28 versus versus IN cord-005646-xhx9pzhj 194 29 24 24 CD cord-005646-xhx9pzhj 194 30 days day NNS cord-005646-xhx9pzhj 194 31 ( ( -LRB- cord-005646-xhx9pzhj 194 32 range range VBP cord-005646-xhx9pzhj 194 33 8 8 CD cord-005646-xhx9pzhj 194 34 -44 -44 NNP cord-005646-xhx9pzhj 194 35 ) ) -RRB- cord-005646-xhx9pzhj 194 36 in in IN cord-005646-xhx9pzhj 194 37 the the DT cord-005646-xhx9pzhj 194 38 [ [ -LRB- cord-005646-xhx9pzhj 194 39 ate eat VBD cord-005646-xhx9pzhj 194 40 treatment treatment NN cord-005646-xhx9pzhj 194 41 group group NN cord-005646-xhx9pzhj 194 42 ( ( -LRB- cord-005646-xhx9pzhj 194 43 p p NN cord-005646-xhx9pzhj 194 44 = = SYM cord-005646-xhx9pzhj 194 45 0.01 0.01 CD cord-005646-xhx9pzhj 194 46 ) ) -RRB- cord-005646-xhx9pzhj 194 47 . . . cord-005646-xhx9pzhj 195 1 The the DT cord-005646-xhx9pzhj 195 2 need need NN cord-005646-xhx9pzhj 195 3 for for IN cord-005646-xhx9pzhj 195 4 supplemental supplemental JJ cord-005646-xhx9pzhj 195 5 oxygen oxygen NN cord-005646-xhx9pzhj 195 6 was be VBD cord-005646-xhx9pzhj 195 7 shorter short JJR cord-005646-xhx9pzhj 195 8 in in IN cord-005646-xhx9pzhj 195 9 the the DT cord-005646-xhx9pzhj 195 10 early early JJ cord-005646-xhx9pzhj 195 11 treatment treatment NN cord-005646-xhx9pzhj 195 12 group group NN cord-005646-xhx9pzhj 195 13 -in -in : cord-005646-xhx9pzhj 195 14 median median JJ cord-005646-xhx9pzhj 195 15 24 24 CD cord-005646-xhx9pzhj 195 16 days day NNS cord-005646-xhx9pzhj 195 17 ( ( -LRB- cord-005646-xhx9pzhj 195 18 range range VBP cord-005646-xhx9pzhj 195 19 10 10 CD cord-005646-xhx9pzhj 195 20 -50 -50 NN cord-005646-xhx9pzhj 195 21 ) ) -RRB- cord-005646-xhx9pzhj 195 22 versus versus IN cord-005646-xhx9pzhj 195 23 40 40 CD cord-005646-xhx9pzhj 195 24 days day NNS cord-005646-xhx9pzhj 195 25 ( ( -LRB- cord-005646-xhx9pzhj 195 26 range range VBP cord-005646-xhx9pzhj 195 27 10 10 CD cord-005646-xhx9pzhj 195 28 -70 -70 CD cord-005646-xhx9pzhj 195 29 ) ) -RRB- cord-005646-xhx9pzhj 196 1 ( ( -LRB- cord-005646-xhx9pzhj 196 2 p p NN cord-005646-xhx9pzhj 196 3 = = SYM cord-005646-xhx9pzhj 196 4 0.2 0.2 CD cord-005646-xhx9pzhj 196 5 , , , cord-005646-xhx9pzhj 196 6 ns ns NNP cord-005646-xhx9pzhj 196 7 ) ) -RRB- cord-005646-xhx9pzhj 196 8 . . . cord-005646-xhx9pzhj 197 1 The the DT cord-005646-xhx9pzhj 197 2 incidence incidence NN cord-005646-xhx9pzhj 197 3 of of IN cord-005646-xhx9pzhj 197 4 chronic chronic JJ cord-005646-xhx9pzhj 197 5 lung lung NN cord-005646-xhx9pzhj 197 6 disease disease NN cord-005646-xhx9pzhj 197 7 was be VBD cord-005646-xhx9pzhj 197 8 lower low JJR cord-005646-xhx9pzhj 197 9 in in IN cord-005646-xhx9pzhj 197 10 the the DT cord-005646-xhx9pzhj 197 11 early early JJ cord-005646-xhx9pzhj 197 12 treatment treatment NN cord-005646-xhx9pzhj 197 13 group group NN cord-005646-xhx9pzhj 197 14 -6 -6 NNP cord-005646-xhx9pzhj 197 15 of of IN cord-005646-xhx9pzhj 197 16 14 14 CD cord-005646-xhx9pzhj 197 17 infants infant NNS cord-005646-xhx9pzhj 197 18 ( ( -LRB- cord-005646-xhx9pzhj 197 19 42.9 42.9 CD cord-005646-xhx9pzhj 197 20 % % NN cord-005646-xhx9pzhj 197 21 ) ) -RRB- cord-005646-xhx9pzhj 197 22 versus versus IN cord-005646-xhx9pzhj 197 23 10 10 CD cord-005646-xhx9pzhj 197 24 of of IN cord-005646-xhx9pzhj 197 25 16 16 CD cord-005646-xhx9pzhj 197 26 patients patient NNS cord-005646-xhx9pzhj 197 27 ( ( -LRB- cord-005646-xhx9pzhj 197 28 62.5 62.5 CD cord-005646-xhx9pzhj 197 29 % % NN cord-005646-xhx9pzhj 197 30 ) ) -RRB- cord-005646-xhx9pzhj 198 1 ( ( -LRB- cord-005646-xhx9pzhj 198 2 ns ns NNP cord-005646-xhx9pzhj 198 3 ) ) -RRB- cord-005646-xhx9pzhj 198 4 . . . cord-005646-xhx9pzhj 199 1 To to TO cord-005646-xhx9pzhj 199 2 evaluate evaluate VB cord-005646-xhx9pzhj 199 3 the the DT cord-005646-xhx9pzhj 199 4 long long JJ cord-005646-xhx9pzhj 199 5 - - HYPH cord-005646-xhx9pzhj 199 6 term term NN cord-005646-xhx9pzhj 199 7 efficacy efficacy NN cord-005646-xhx9pzhj 199 8 of of IN cord-005646-xhx9pzhj 199 9 early early JJ cord-005646-xhx9pzhj 199 10 DEX DEX NNP cord-005646-xhx9pzhj 199 11 treatment treatment NN cord-005646-xhx9pzhj 199 12 we -PRON- PRP cord-005646-xhx9pzhj 199 13 performed perform VBD cord-005646-xhx9pzhj 199 14 a a DT cord-005646-xhx9pzhj 199 15 respiratory respiratory JJ cord-005646-xhx9pzhj 199 16 function function NN cord-005646-xhx9pzhj 199 17 test test NN cord-005646-xhx9pzhj 199 18 in in IN cord-005646-xhx9pzhj 199 19 the the DT cord-005646-xhx9pzhj 199 20 age age NN cord-005646-xhx9pzhj 199 21 of of IN cord-005646-xhx9pzhj 199 22 3 3 CD cord-005646-xhx9pzhj 199 23 -6 -6 NNP cord-005646-xhx9pzhj 199 24 months month NNS cord-005646-xhx9pzhj 199 25 using use VBG cord-005646-xhx9pzhj 199 26 an an DT cord-005646-xhx9pzhj 199 27 infant infant NN cord-005646-xhx9pzhj 199 28 whole whole JJ cord-005646-xhx9pzhj 199 29 body body NN cord-005646-xhx9pzhj 199 30 - - HYPH cord-005646-xhx9pzhj 199 31 plethysmograph plethysmograph NN cord-005646-xhx9pzhj 199 32 . . . cord-005646-xhx9pzhj 200 1 The the DT cord-005646-xhx9pzhj 200 2 intrathoracic intrathoracic JJ cord-005646-xhx9pzhj 200 3 gas gas NN cord-005646-xhx9pzhj 200 4 volume volume NN cord-005646-xhx9pzhj 200 5 ( ( -LRB- cord-005646-xhx9pzhj 200 6 ITGV ITGV NNP cord-005646-xhx9pzhj 200 7 ) ) -RRB- cord-005646-xhx9pzhj 200 8 , , , cord-005646-xhx9pzhj 200 9 the the DT cord-005646-xhx9pzhj 200 10 airway airway NN cord-005646-xhx9pzhj 200 11 resistance resistance NN cord-005646-xhx9pzhj 200 12 ( ( -LRB- cord-005646-xhx9pzhj 200 13 R.w R.w NNP cord-005646-xhx9pzhj 200 14 ) ) -RRB- cord-005646-xhx9pzhj 200 15 and and CC cord-005646-xhx9pzhj 200 16 the the DT cord-005646-xhx9pzhj 200 17 airway airway NN cord-005646-xhx9pzhj 200 18 conductance conductance NN cord-005646-xhx9pzhj 200 19 ( ( -LRB- cord-005646-xhx9pzhj 200 20 Gaw Gaw NNP cord-005646-xhx9pzhj 200 21 ) ) -RRB- cord-005646-xhx9pzhj 200 22 were be VBD cord-005646-xhx9pzhj 200 23 measured measure VBN cord-005646-xhx9pzhj 200 24 and and CC cord-005646-xhx9pzhj 200 25 no no DT cord-005646-xhx9pzhj 200 26 significant significant JJ cord-005646-xhx9pzhj 200 27 differences difference NNS cord-005646-xhx9pzhj 200 28 could could MD cord-005646-xhx9pzhj 200 29 be be VB cord-005646-xhx9pzhj 200 30 detected detect VBN cord-005646-xhx9pzhj 200 31 between between IN cord-005646-xhx9pzhj 200 32 the the DT cord-005646-xhx9pzhj 200 33 groups group NNS cord-005646-xhx9pzhj 200 34 . . . cord-005646-xhx9pzhj 201 1 The the DT cord-005646-xhx9pzhj 201 2 frequency frequency NN cord-005646-xhx9pzhj 201 3 of of IN cord-005646-xhx9pzhj 201 4 adverse adverse JJ cord-005646-xhx9pzhj 201 5 effects effect NNS cord-005646-xhx9pzhj 201 6 due due IN cord-005646-xhx9pzhj 201 7 to to IN cord-005646-xhx9pzhj 201 8 DEX DEX NNP cord-005646-xhx9pzhj 201 9 therapy therapy NN cord-005646-xhx9pzhj 201 10 was be VBD cord-005646-xhx9pzhj 201 11 found find VBN cord-005646-xhx9pzhj 201 12 to to TO cord-005646-xhx9pzhj 201 13 be be VB cord-005646-xhx9pzhj 201 14 without without IN cord-005646-xhx9pzhj 201 15 significant significant JJ cord-005646-xhx9pzhj 201 16 differences difference NNS cord-005646-xhx9pzhj 201 17 between between IN cord-005646-xhx9pzhj 201 18 the the DT cord-005646-xhx9pzhj 201 19 early early JJ cord-005646-xhx9pzhj 201 20 and and CC cord-005646-xhx9pzhj 201 21 the the DT cord-005646-xhx9pzhj 201 22 late late JJ cord-005646-xhx9pzhj 201 23 treatment treatment NN cord-005646-xhx9pzhj 201 24 group group NN cord-005646-xhx9pzhj 201 25 . . . cord-005646-xhx9pzhj 202 1 We -PRON- PRP cord-005646-xhx9pzhj 202 2 conclude conclude VBP cord-005646-xhx9pzhj 202 3 that that IN cord-005646-xhx9pzhj 202 4 early early JJ cord-005646-xhx9pzhj 202 5 DEX DEX NNP cord-005646-xhx9pzhj 202 6 treatment treatment NN cord-005646-xhx9pzhj 202 7 had have VBD cord-005646-xhx9pzhj 202 8 short short JJ cord-005646-xhx9pzhj 202 9 - - HYPH cord-005646-xhx9pzhj 202 10 term term NN cord-005646-xhx9pzhj 202 11 improvements improvement NNS cord-005646-xhx9pzhj 202 12 in in IN cord-005646-xhx9pzhj 202 13 pulmonary pulmonary JJ cord-005646-xhx9pzhj 202 14 outcome outcome NN cord-005646-xhx9pzhj 202 15 in in IN cord-005646-xhx9pzhj 202 16 our -PRON- PRP$ cord-005646-xhx9pzhj 202 17 study study NN cord-005646-xhx9pzhj 202 18 population population NN cord-005646-xhx9pzhj 202 19 , , , cord-005646-xhx9pzhj 202 20 long long JJ cord-005646-xhx9pzhj 202 21 - - HYPH cord-005646-xhx9pzhj 202 22 term term NN cord-005646-xhx9pzhj 202 23 efficacy efficacy NN cord-005646-xhx9pzhj 202 24 however however RB cord-005646-xhx9pzhj 202 25 , , , cord-005646-xhx9pzhj 202 26 remained remain VBD cord-005646-xhx9pzhj 202 27 unproven unproven JJ cord-005646-xhx9pzhj 202 28 . . . cord-005646-xhx9pzhj 203 1 Several several JJ cord-005646-xhx9pzhj 203 2 factors factor NNS cord-005646-xhx9pzhj 203 3 contribute contribute VBP cord-005646-xhx9pzhj 203 4 to to IN cord-005646-xhx9pzhj 203 5 the the DT cord-005646-xhx9pzhj 203 6 development development NN cord-005646-xhx9pzhj 203 7 of of IN cord-005646-xhx9pzhj 203 8 chronic chronic JJ cord-005646-xhx9pzhj 203 9 lung lung NN cord-005646-xhx9pzhj 203 10 disease disease NN cord-005646-xhx9pzhj 203 11 ( ( -LRB- cord-005646-xhx9pzhj 203 12 CLD CLD NNP cord-005646-xhx9pzhj 203 13 ) ) -RRB- cord-005646-xhx9pzhj 203 14 in in IN cord-005646-xhx9pzhj 203 15 premature premature JJ cord-005646-xhx9pzhj 203 16 infants infant NNS cord-005646-xhx9pzhj 203 17 including include VBG cord-005646-xhx9pzhj 203 18 structural structural JJ cord-005646-xhx9pzhj 203 19 immaturity immaturity NN cord-005646-xhx9pzhj 203 20 of of IN cord-005646-xhx9pzhj 203 21 the the DT cord-005646-xhx9pzhj 203 22 lung lung NN cord-005646-xhx9pzhj 203 23 , , , cord-005646-xhx9pzhj 203 24 mechanical mechanical JJ cord-005646-xhx9pzhj 203 25 ventilation ventilation NN cord-005646-xhx9pzhj 203 26 , , , cord-005646-xhx9pzhj 203 27 and and CC cord-005646-xhx9pzhj 203 28 oxidative oxidative JJ cord-005646-xhx9pzhj 203 29 stress stress NN cord-005646-xhx9pzhj 203 30 . . . cord-005646-xhx9pzhj 204 1 Reactive reactive JJ cord-005646-xhx9pzhj 204 2 oxygen oxygen NN cord-005646-xhx9pzhj 204 3 species specie NNS cord-005646-xhx9pzhj 204 4 are be VBP cord-005646-xhx9pzhj 204 5 formed form VBN cord-005646-xhx9pzhj 204 6 during during IN cord-005646-xhx9pzhj 204 7 normal normal JJ cord-005646-xhx9pzhj 204 8 cellular cellular JJ cord-005646-xhx9pzhj 204 9 metabolism metabolism NN cord-005646-xhx9pzhj 204 10 but but CC cord-005646-xhx9pzhj 204 11 they -PRON- PRP cord-005646-xhx9pzhj 204 12 are be VBP cord-005646-xhx9pzhj 204 13 generated generate VBN cord-005646-xhx9pzhj 204 14 in in IN cord-005646-xhx9pzhj 204 15 higher high JJR cord-005646-xhx9pzhj 204 16 concentrations concentration NNS cord-005646-xhx9pzhj 204 17 during during IN cord-005646-xhx9pzhj 204 18 inflammation inflammation NN cord-005646-xhx9pzhj 204 19 or or CC cord-005646-xhx9pzhj 204 20 inhalation inhalation NN cord-005646-xhx9pzhj 204 21 of of IN cord-005646-xhx9pzhj 204 22 high high JJ cord-005646-xhx9pzhj 204 23 oxygen oxygen NN cord-005646-xhx9pzhj 204 24 concentrations concentration NNS cord-005646-xhx9pzhj 204 25 . . . cord-005646-xhx9pzhj 205 1 To to TO cord-005646-xhx9pzhj 205 2 study study VB cord-005646-xhx9pzhj 205 3 the the DT cord-005646-xhx9pzhj 205 4 relationship relationship NN cord-005646-xhx9pzhj 205 5 between between IN cord-005646-xhx9pzhj 205 6 increased increase VBN cord-005646-xhx9pzhj 205 7 oxidative oxidative JJ cord-005646-xhx9pzhj 205 8 stress stress NN cord-005646-xhx9pzhj 205 9 , , , cord-005646-xhx9pzhj 205 10 antioxidants antioxidant NNS cord-005646-xhx9pzhj 205 11 and and CC cord-005646-xhx9pzhj 205 12 the the DT cord-005646-xhx9pzhj 205 13 development development NN cord-005646-xhx9pzhj 205 14 of of IN cord-005646-xhx9pzhj 205 15 CLD CLD NNP cord-005646-xhx9pzhj 205 16 we -PRON- PRP cord-005646-xhx9pzhj 205 17 examined examine VBD cord-005646-xhx9pzhj 205 18 102 102 CD cord-005646-xhx9pzhj 205 19 ventilated ventilate VBD cord-005646-xhx9pzhj 205 20 premature premature JJ cord-005646-xhx9pzhj 205 21 infants infant NNS cord-005646-xhx9pzhj 205 22 with with IN cord-005646-xhx9pzhj 205 23 birth birth NN cord-005646-xhx9pzhj 205 24 weights weight NNS cord-005646-xhx9pzhj 205 25 below below IN cord-005646-xhx9pzhj 205 26 t500 t500 NNP cord-005646-xhx9pzhj 205 27 g g NNP cord-005646-xhx9pzhj 205 28 . . . cord-005646-xhx9pzhj 206 1 32 32 CD cord-005646-xhx9pzhj 206 2 infants infant NNS cord-005646-xhx9pzhj 206 3 developed develop VBD cord-005646-xhx9pzhj 206 4 severe severe JJ cord-005646-xhx9pzhj 206 5 chronic chronic JJ cord-005646-xhx9pzhj 206 6 lung lung NN cord-005646-xhx9pzhj 206 7 disease disease NN cord-005646-xhx9pzhj 206 8 of of IN cord-005646-xhx9pzhj 206 9 prematurity prematurity NN cord-005646-xhx9pzhj 206 10 ( ( -LRB- cord-005646-xhx9pzhj 206 11 CLD CLD NNP cord-005646-xhx9pzhj 206 12 ) ) -RRB- cord-005646-xhx9pzhj 206 13 , , , cord-005646-xhx9pzhj 206 14 defined define VBN cord-005646-xhx9pzhj 206 15 by by IN cord-005646-xhx9pzhj 206 16 radiological radiological JJ cord-005646-xhx9pzhj 206 17 signs sign NNS cord-005646-xhx9pzhj 206 18 of of IN cord-005646-xhx9pzhj 206 19 CLD CLD NNP cord-005646-xhx9pzhj 206 20 and and CC cord-005646-xhx9pzhj 206 21 an an DT cord-005646-xhx9pzhj 206 22 increased increase VBN cord-005646-xhx9pzhj 206 23 oxygen oxygen NN cord-005646-xhx9pzhj 206 24 requirement requirement NN cord-005646-xhx9pzhj 206 25 at at IN cord-005646-xhx9pzhj 206 26 a a DT cord-005646-xhx9pzhj 206 27 postconceptional postconceptional JJ cord-005646-xhx9pzhj 206 28 age age NN cord-005646-xhx9pzhj 206 29 of of IN cord-005646-xhx9pzhj 206 30 36 36 CD cord-005646-xhx9pzhj 206 31 weeks week NNS cord-005646-xhx9pzhj 206 32 , , , cord-005646-xhx9pzhj 206 33 and and CC cord-005646-xhx9pzhj 206 34 29 29 CD cord-005646-xhx9pzhj 206 35 infants infant NNS cord-005646-xhx9pzhj 206 36 had have VBD cord-005646-xhx9pzhj 206 37 moderate moderate JJ cord-005646-xhx9pzhj 206 38 CLD CLD NNP cord-005646-xhx9pzhj 206 39 with with IN cord-005646-xhx9pzhj 206 40 an an DT cord-005646-xhx9pzhj 206 41 increased increase VBN cord-005646-xhx9pzhj 206 42 oxygen oxygen NN cord-005646-xhx9pzhj 206 43 requirement requirement NN cord-005646-xhx9pzhj 206 44 on on IN cord-005646-xhx9pzhj 206 45 day day NN cord-005646-xhx9pzhj 206 46 28 28 CD cord-005646-xhx9pzhj 206 47 but but CC cord-005646-xhx9pzhj 206 48 not not RB cord-005646-xhx9pzhj 206 49 at at IN cord-005646-xhx9pzhj 206 50 an an DT cord-005646-xhx9pzhj 206 51 age age NN cord-005646-xhx9pzhj 206 52 of of IN cord-005646-xhx9pzhj 206 53 36 36 CD cord-005646-xhx9pzhj 206 54 weeks week NNS cord-005646-xhx9pzhj 206 55 . . . cord-005646-xhx9pzhj 207 1 Ventilator Ventilator NNP cord-005646-xhx9pzhj 207 2 settings setting NNS cord-005646-xhx9pzhj 207 3 ( ( -LRB- cord-005646-xhx9pzhj 207 4 FiO2 FiO2 NNS cord-005646-xhx9pzhj 207 5 , , , cord-005646-xhx9pzhj 207 6 peak peak NN cord-005646-xhx9pzhj 207 7 inspiratory inspiratory JJ cord-005646-xhx9pzhj 207 8 and and CC cord-005646-xhx9pzhj 207 9 mean mean JJ cord-005646-xhx9pzhj 207 10 airway airway NN cord-005646-xhx9pzhj 207 11 pressure pressure NN cord-005646-xhx9pzhj 207 12 ) ) -RRB- cord-005646-xhx9pzhj 207 13 and and CC cord-005646-xhx9pzhj 207 14 the the DT cord-005646-xhx9pzhj 207 15 incidence incidence NN cord-005646-xhx9pzhj 207 16 of of IN cord-005646-xhx9pzhj 207 17 early early JJ cord-005646-xhx9pzhj 207 18 - - HYPH cord-005646-xhx9pzhj 207 19 onset onset NN cord-005646-xhx9pzhj 207 20 - - HYPH cord-005646-xhx9pzhj 207 21 sepsis sepsis NN cord-005646-xhx9pzhj 207 22 were be VBD cord-005646-xhx9pzhj 207 23 significantly significantly RB cord-005646-xhx9pzhj 207 24 higher high JJR cord-005646-xhx9pzhj 207 25 in in IN cord-005646-xhx9pzhj 207 26 the the DT cord-005646-xhx9pzhj 207 27 severe severe JJ cord-005646-xhx9pzhj 207 28 CLD CLD NNP cord-005646-xhx9pzhj 207 29 group group NN cord-005646-xhx9pzhj 207 30 than than IN cord-005646-xhx9pzhj 207 31 in in IN cord-005646-xhx9pzhj 207 32 infants infant NNS cord-005646-xhx9pzhj 207 33 with with IN cord-005646-xhx9pzhj 207 34 moderate moderate JJ cord-005646-xhx9pzhj 207 35 CLD cld NN cord-005646-xhx9pzhj 207 36 or or CC cord-005646-xhx9pzhj 207 37 without without IN cord-005646-xhx9pzhj 207 38 CLD CLD NNP cord-005646-xhx9pzhj 207 39 ( ( -LRB- cord-005646-xhx9pzhj 207 40 n=41 n=41 RB cord-005646-xhx9pzhj 207 41 ) ) -RRB- cord-005646-xhx9pzhj 207 42 during during IN cord-005646-xhx9pzhj 207 43 the the DT cord-005646-xhx9pzhj 207 44 first first JJ cord-005646-xhx9pzhj 207 45 week week NN cord-005646-xhx9pzhj 207 46 of of IN cord-005646-xhx9pzhj 207 47 life life NN cord-005646-xhx9pzhj 207 48 . . . cord-005646-xhx9pzhj 208 1 Plasma plasma NN cord-005646-xhx9pzhj 208 2 concentrations concentration NNS cord-005646-xhx9pzhj 208 3 of of IN cord-005646-xhx9pzhj 208 4 the the DT cord-005646-xhx9pzhj 208 5 two two CD cord-005646-xhx9pzhj 208 6 antioxidative antioxidative JJ cord-005646-xhx9pzhj 208 7 substances substance NNS cord-005646-xhx9pzhj 208 8 bilirubin bilirubin VBP cord-005646-xhx9pzhj 208 9 and and CC cord-005646-xhx9pzhj 208 10 uric uric NN cord-005646-xhx9pzhj 208 11 acid acid NN cord-005646-xhx9pzhj 208 12 ( ( -LRB- cord-005646-xhx9pzhj 208 13 UA UA NNP cord-005646-xhx9pzhj 208 14 ) ) -RRB- cord-005646-xhx9pzhj 208 15 were be VBD cord-005646-xhx9pzhj 208 16 comparable comparable JJ cord-005646-xhx9pzhj 208 17 in in IN cord-005646-xhx9pzhj 208 18 all all DT cord-005646-xhx9pzhj 208 19 groups group NNS cord-005646-xhx9pzhj 208 20 during during IN cord-005646-xhx9pzhj 208 21 the the DT cord-005646-xhx9pzhj 208 22 first first JJ cord-005646-xhx9pzhj 208 23 days day NNS cord-005646-xhx9pzhj 208 24 of of IN cord-005646-xhx9pzhj 208 25 life life NN cord-005646-xhx9pzhj 208 26 . . . cord-005646-xhx9pzhj 209 1 However however RB cord-005646-xhx9pzhj 209 2 , , , cord-005646-xhx9pzhj 209 3 on on IN cord-005646-xhx9pzhj 209 4 day day NN cord-005646-xhx9pzhj 209 5 seven seven CD cord-005646-xhx9pzhj 209 6 bilirubin bilirubin NN cord-005646-xhx9pzhj 209 7 and and CC cord-005646-xhx9pzhj 209 8 UA UA NNP cord-005646-xhx9pzhj 209 9 were be VBD cord-005646-xhx9pzhj 209 10 significantly significantly RB cord-005646-xhx9pzhj 209 11 decreased decrease VBN cord-005646-xhx9pzhj 209 12 in in IN cord-005646-xhx9pzhj 209 13 the the DT cord-005646-xhx9pzhj 209 14 plasma plasma NN cord-005646-xhx9pzhj 209 15 of of IN cord-005646-xhx9pzhj 209 16 infants infant NNS cord-005646-xhx9pzhj 209 17 with with IN cord-005646-xhx9pzhj 209 18 severe severe JJ cord-005646-xhx9pzhj 209 19 and and CC cord-005646-xhx9pzhj 209 20 moderate moderate JJ cord-005646-xhx9pzhj 209 21 CLD cld NN cord-005646-xhx9pzhj 209 22 compared compare VBN cord-005646-xhx9pzhj 209 23 to to IN cord-005646-xhx9pzhj 209 24 the the DT cord-005646-xhx9pzhj 209 25 non non JJ cord-005646-xhx9pzhj 209 26 CLD CLD NNP cord-005646-xhx9pzhj 209 27 group group NN cord-005646-xhx9pzhj 209 28 ( ( -LRB- cord-005646-xhx9pzhj 209 29 p p NN cord-005646-xhx9pzhj 209 30 < < XX cord-005646-xhx9pzhj 209 31 O.001 o.001 XX cord-005646-xhx9pzhj 209 32 ) ) -RRB- cord-005646-xhx9pzhj 209 33 . . . cord-005646-xhx9pzhj 210 1 There there EX cord-005646-xhx9pzhj 210 2 was be VBD cord-005646-xhx9pzhj 210 3 no no DT cord-005646-xhx9pzhj 210 4 difference difference NN cord-005646-xhx9pzhj 210 5 between between IN cord-005646-xhx9pzhj 210 6 both both CC cord-005646-xhx9pzhj 210 7 CLD CLD NNP cord-005646-xhx9pzhj 210 8 groups group NNS cord-005646-xhx9pzhj 210 9 . . . cord-005646-xhx9pzhj 211 1 In in IN cord-005646-xhx9pzhj 211 2 serially serially RB cord-005646-xhx9pzhj 211 3 obtained obtain VBN cord-005646-xhx9pzhj 211 4 tracheal tracheal JJ cord-005646-xhx9pzhj 211 5 aspirate aspirate NN cord-005646-xhx9pzhj 211 6 fluids fluid NNS cord-005646-xhx9pzhj 211 7 ( ( -LRB- cord-005646-xhx9pzhj 211 8 TAF TAF NNP cord-005646-xhx9pzhj 211 9 ) ) -RRB- cord-005646-xhx9pzhj 211 10 malondialdehyde malondialdehyde NNP cord-005646-xhx9pzhj 211 11 ( ( -LRB- cord-005646-xhx9pzhj 211 12 MDA MDA NNP cord-005646-xhx9pzhj 211 13 ) ) -RRB- cord-005646-xhx9pzhj 211 14 was be VBD cord-005646-xhx9pzhj 211 15 measured measure VBN cord-005646-xhx9pzhj 211 16 by by IN cord-005646-xhx9pzhj 211 17 HPLC HPLC NNP cord-005646-xhx9pzhj 211 18 as as IN cord-005646-xhx9pzhj 211 19 an an DT cord-005646-xhx9pzhj 211 20 indicator indicator NN cord-005646-xhx9pzhj 211 21 of of IN cord-005646-xhx9pzhj 211 22 lipid lipid NN cord-005646-xhx9pzhj 211 23 peroxidation peroxidation NN cord-005646-xhx9pzhj 211 24 reflecting reflect VBG cord-005646-xhx9pzhj 211 25 oxygen oxygen NN cord-005646-xhx9pzhj 211 26 injury injury NN cord-005646-xhx9pzhj 211 27 of of IN cord-005646-xhx9pzhj 211 28 the the DT cord-005646-xhx9pzhj 211 29 lung lung NN cord-005646-xhx9pzhj 211 30 . . . cord-005646-xhx9pzhj 212 1 UA UA NNP cord-005646-xhx9pzhj 212 2 was be VBD cord-005646-xhx9pzhj 212 3 found find VBN cord-005646-xhx9pzhj 212 4 in in IN cord-005646-xhx9pzhj 212 5 higher high JJR cord-005646-xhx9pzhj 212 6 concentrations concentration NNS cord-005646-xhx9pzhj 212 7 in in IN cord-005646-xhx9pzhj 212 8 TAF TAF NNP cord-005646-xhx9pzhj 212 9 than than IN cord-005646-xhx9pzhj 212 10 bilirubin bilirubin NN cord-005646-xhx9pzhj 212 11 . . . cord-005646-xhx9pzhj 213 1 UA UA NNP cord-005646-xhx9pzhj 213 2 has have VBZ cord-005646-xhx9pzhj 213 3 been be VBN cord-005646-xhx9pzhj 213 4 proven prove VBN cord-005646-xhx9pzhj 213 5 to to TO cord-005646-xhx9pzhj 213 6 be be VB cord-005646-xhx9pzhj 213 7 a a DT cord-005646-xhx9pzhj 213 8 potent potent JJ cord-005646-xhx9pzhj 213 9 antioxidant antioxidant NN cord-005646-xhx9pzhj 213 10 , , , cord-005646-xhx9pzhj 213 11 capable capable JJ cord-005646-xhx9pzhj 213 12 to to TO cord-005646-xhx9pzhj 213 13 react react VB cord-005646-xhx9pzhj 213 14 especially especially RB cord-005646-xhx9pzhj 213 15 with with IN cord-005646-xhx9pzhj 213 16 hydroxyl hydroxyl NN cord-005646-xhx9pzhj 213 17 radicals radical NNS cord-005646-xhx9pzhj 213 18 and and CC cord-005646-xhx9pzhj 213 19 hydrochlerous hydrochlerous JJ cord-005646-xhx9pzhj 213 20 acid acid NN cord-005646-xhx9pzhj 213 21 , , , cord-005646-xhx9pzhj 213 22 which which WDT cord-005646-xhx9pzhj 213 23 play play VBP cord-005646-xhx9pzhj 213 24 an an DT cord-005646-xhx9pzhj 213 25 important important JJ cord-005646-xhx9pzhj 213 26 role role NN cord-005646-xhx9pzhj 213 27 in in IN cord-005646-xhx9pzhj 213 28 the the DT cord-005646-xhx9pzhj 213 29 induction induction NN cord-005646-xhx9pzhj 213 30 of of IN cord-005646-xhx9pzhj 213 31 lipid lipid NN cord-005646-xhx9pzhj 213 32 peroxidation peroxidation NN cord-005646-xhx9pzhj 213 33 . . . cord-005646-xhx9pzhj 214 1 Infants infant NNS cord-005646-xhx9pzhj 214 2 with with IN cord-005646-xhx9pzhj 214 3 severe severe JJ cord-005646-xhx9pzhj 214 4 CLD CLD NNP cord-005646-xhx9pzhj 214 5 had have VBD cord-005646-xhx9pzhj 214 6 significantly significantly RB cord-005646-xhx9pzhj 214 7 higher high JJR cord-005646-xhx9pzhj 214 8 MDNUA MDNUA NNP cord-005646-xhx9pzhj 214 9 ratios ratio NNS cord-005646-xhx9pzhj 214 10 in in IN cord-005646-xhx9pzhj 214 11 TAF TAF NNP cord-005646-xhx9pzhj 214 12 from from IN cord-005646-xhx9pzhj 214 13 day day NN cord-005646-xhx9pzhj 214 14 5 5 CD cord-005646-xhx9pzhj 214 15 to to TO cord-005646-xhx9pzhj 214 16 14 14 CD cord-005646-xhx9pzhj 214 17 compared compare VBN cord-005646-xhx9pzhj 214 18 to to IN cord-005646-xhx9pzhj 214 19 the the DT cord-005646-xhx9pzhj 214 20 non non JJ cord-005646-xhx9pzhj 214 21 - - JJ cord-005646-xhx9pzhj 214 22 CLD cld JJ cord-005646-xhx9pzhj 214 23 group group NN cord-005646-xhx9pzhj 214 24 ( ( -LRB- cord-005646-xhx9pzhj 214 25 p p NN cord-005646-xhx9pzhj 214 26 < < XX cord-005646-xhx9pzhj 214 27 O.01 o.01 CD cord-005646-xhx9pzhj 214 28 ) ) -RRB- cord-005646-xhx9pzhj 214 29 . . . cord-005646-xhx9pzhj 215 1 MDNUA MDNUA NNP cord-005646-xhx9pzhj 215 2 ratios ratio NNS cord-005646-xhx9pzhj 215 3 in in IN cord-005646-xhx9pzhj 215 4 TAF TAF NNP cord-005646-xhx9pzhj 215 5 of of IN cord-005646-xhx9pzhj 215 6 infants infant NNS cord-005646-xhx9pzhj 215 7 with with IN cord-005646-xhx9pzhj 215 8 moderate moderate JJ cord-005646-xhx9pzhj 215 9 CLD CLD NNP cord-005646-xhx9pzhj 215 10 were be VBD cord-005646-xhx9pzhj 215 11 significantly significantly RB cord-005646-xhx9pzhj 215 12 higher high JJR cord-005646-xhx9pzhj 215 13 from from IN cord-005646-xhx9pzhj 215 14 day day NN cord-005646-xhx9pzhj 215 15 7 7 CD cord-005646-xhx9pzhj 215 16 on on RB cord-005646-xhx9pzhj 215 17 but but CC cord-005646-xhx9pzhj 215 18 still still RB cord-005646-xhx9pzhj 215 19 lower low JJR cord-005646-xhx9pzhj 215 20 than than IN cord-005646-xhx9pzhj 215 21 in in IN cord-005646-xhx9pzhj 215 22 the the DT cord-005646-xhx9pzhj 215 23 severe severe JJ cord-005646-xhx9pzhj 215 24 CLD CLD NNP cord-005646-xhx9pzhj 215 25 group group NN cord-005646-xhx9pzhj 215 26 . . . cord-005646-xhx9pzhj 216 1 In in IN cord-005646-xhx9pzhj 216 2 addition addition NN cord-005646-xhx9pzhj 216 3 , , , cord-005646-xhx9pzhj 216 4 the the DT cord-005646-xhx9pzhj 216 5 ratio ratio NN cord-005646-xhx9pzhj 216 6 oxidized oxidize VBN cord-005646-xhx9pzhj 216 7 / / SYM cord-005646-xhx9pzhj 216 8 reduced reduce VBN cord-005646-xhx9pzhj 216 9 glutathione glutathione NN cord-005646-xhx9pzhj 216 10 was be VBD cord-005646-xhx9pzhj 216 11 significantly significantly RB cord-005646-xhx9pzhj 216 12 increased increase VBN cord-005646-xhx9pzhj 216 13 in in IN cord-005646-xhx9pzhj 216 14 TAF TAF NNP cord-005646-xhx9pzhj 216 15 of of IN cord-005646-xhx9pzhj 216 16 infants infant NNS cord-005646-xhx9pzhj 216 17 with with IN cord-005646-xhx9pzhj 216 18 CLD CLD NNP cord-005646-xhx9pzhj 216 19 compared compare VBN cord-005646-xhx9pzhj 216 20 to to IN cord-005646-xhx9pzhj 216 21 infants infant NNS cord-005646-xhx9pzhj 216 22 without without IN cord-005646-xhx9pzhj 216 23 CLD CLD NNP cord-005646-xhx9pzhj 216 24 between between IN cord-005646-xhx9pzhj 216 25 day day NN cord-005646-xhx9pzhj 216 26 5 5 CD cord-005646-xhx9pzhj 216 27 and and CC cord-005646-xhx9pzhj 216 28 14 14 CD cord-005646-xhx9pzhj 216 29 . . . cord-005646-xhx9pzhj 217 1 The the DT cord-005646-xhx9pzhj 217 2 data datum NNS cord-005646-xhx9pzhj 217 3 support support VBP cord-005646-xhx9pzhj 217 4 the the DT cord-005646-xhx9pzhj 217 5 hypothesis hypothesis NN cord-005646-xhx9pzhj 217 6 that that IN cord-005646-xhx9pzhj 217 7 an an DT cord-005646-xhx9pzhj 217 8 imbalance imbalance NN cord-005646-xhx9pzhj 217 9 of of IN cord-005646-xhx9pzhj 217 10 oxidative oxidative JJ cord-005646-xhx9pzhj 217 11 stress stress NN cord-005646-xhx9pzhj 217 12 and and CC cord-005646-xhx9pzhj 217 13 antioxidant antioxidant NN cord-005646-xhx9pzhj 217 14 defense defense NN cord-005646-xhx9pzhj 217 15 contributs contribut NNS cord-005646-xhx9pzhj 217 16 to to IN cord-005646-xhx9pzhj 217 17 the the DT cord-005646-xhx9pzhj 217 18 onset onset NN cord-005646-xhx9pzhj 217 19 of of IN cord-005646-xhx9pzhj 217 20 CLD CLD NNP cord-005646-xhx9pzhj 217 21 at at IN cord-005646-xhx9pzhj 217 22 the the DT cord-005646-xhx9pzhj 217 23 end end NN cord-005646-xhx9pzhj 217 24 of of IN cord-005646-xhx9pzhj 217 25 the the DT cord-005646-xhx9pzhj 217 26 first first JJ cord-005646-xhx9pzhj 217 27 week week NN cord-005646-xhx9pzhj 217 28 of of IN cord-005646-xhx9pzhj 217 29 life life NN cord-005646-xhx9pzhj 217 30 . . . cord-005646-xhx9pzhj 218 1 Introduction introduction NN cord-005646-xhx9pzhj 218 2 . . . cord-005646-xhx9pzhj 219 1 Rocuronium rocuronium NN cord-005646-xhx9pzhj 219 2 bromide bromide NN cord-005646-xhx9pzhj 219 3 ( ( -LRB- cord-005646-xhx9pzhj 219 4 Roe Roe NNP cord-005646-xhx9pzhj 219 5 ) ) -RRB- cord-005646-xhx9pzhj 219 6 , , , cord-005646-xhx9pzhj 219 7 a a DT cord-005646-xhx9pzhj 219 8 neuromuscular neuromuscular NN cord-005646-xhx9pzhj 219 9 blocking block VBG cord-005646-xhx9pzhj 219 10 agent agent NN cord-005646-xhx9pzhj 219 11 with with IN cord-005646-xhx9pzhj 219 12 an an DT cord-005646-xhx9pzhj 219 13 onset onset NN cord-005646-xhx9pzhj 219 14 time time NN cord-005646-xhx9pzhj 219 15 dose dose NN cord-005646-xhx9pzhj 219 16 to to IN cord-005646-xhx9pzhj 219 17 that that DT cord-005646-xhx9pzhj 219 18 of of IN cord-005646-xhx9pzhj 219 19 succinyleholine succinyleholine NN cord-005646-xhx9pzhj 219 20 l'z l'z NNS cord-005646-xhx9pzhj 219 21 , , , cord-005646-xhx9pzhj 219 22 has have VBZ cord-005646-xhx9pzhj 219 23 been be VBN cord-005646-xhx9pzhj 219 24 studied study VBN cord-005646-xhx9pzhj 219 25 in in IN cord-005646-xhx9pzhj 219 26 American American NNP cord-005646-xhx9pzhj 219 27 Society Society NNP cord-005646-xhx9pzhj 219 28 of of IN cord-005646-xhx9pzhj 219 29 Anesthesiologists Anesthesiologists NNPS cord-005646-xhx9pzhj 219 30 ' ' POS cord-005646-xhx9pzhj 219 31 Physical physical JJ cord-005646-xhx9pzhj 219 32 Status status NN cord-005646-xhx9pzhj 219 33 ( ( -LRB- cord-005646-xhx9pzhj 219 34 ASA ASA NNP cord-005646-xhx9pzhj 219 35 ) ) -RRB- cord-005646-xhx9pzhj 220 1 I -PRON- PRP cord-005646-xhx9pzhj 220 2 or or CC cord-005646-xhx9pzhj 220 3 II II NNP cord-005646-xhx9pzhj 220 4 pedlatrie pedlatrie NN cord-005646-xhx9pzhj 220 5 patients patient NNS cord-005646-xhx9pzhj 220 6 under under IN cord-005646-xhx9pzhj 220 7 non non JJ cord-005646-xhx9pzhj 220 8 - - JJ cord-005646-xhx9pzhj 220 9 critical critical JJ cord-005646-xhx9pzhj 220 10 elective elective JJ cord-005646-xhx9pzhj 220 11 conditions condition NNS cord-005646-xhx9pzhj 220 12 . . . cord-005646-xhx9pzhj 221 1 There there EX cord-005646-xhx9pzhj 221 2 is be VBZ cord-005646-xhx9pzhj 221 3 a a DT cord-005646-xhx9pzhj 221 4 paucity paucity NN cord-005646-xhx9pzhj 221 5 of of IN cord-005646-xhx9pzhj 221 6 studies study NNS cord-005646-xhx9pzhj 221 7 looking look VBG cord-005646-xhx9pzhj 221 8 at at IN cord-005646-xhx9pzhj 221 9 the the DT cord-005646-xhx9pzhj 221 10 pharmacodynamics pharmacodynamic NNS cord-005646-xhx9pzhj 221 11 of of IN cord-005646-xhx9pzhj 221 12 Roc Roc NNP cord-005646-xhx9pzhj 221 13 under under IN cord-005646-xhx9pzhj 221 14 emergent emergent JJ cord-005646-xhx9pzhj 221 15 conditions condition NNS cord-005646-xhx9pzhj 221 16 , , , cord-005646-xhx9pzhj 221 17 involving involve VBG cord-005646-xhx9pzhj 221 18 pediatric pediatric JJ cord-005646-xhx9pzhj 221 19 patients patient NNS cord-005646-xhx9pzhj 221 20 who who WP cord-005646-xhx9pzhj 221 21 are be VBP cord-005646-xhx9pzhj 221 22 ASA ASA NNP cord-005646-xhx9pzhj 221 23 III III NNP cord-005646-xhx9pzhj 221 24 or or CC cord-005646-xhx9pzhj 221 25 IV IV NNP cord-005646-xhx9pzhj 221 26 , , , cord-005646-xhx9pzhj 221 27 without without IN cord-005646-xhx9pzhj 221 28 the the DT cord-005646-xhx9pzhj 221 29 use use NN cord-005646-xhx9pzhj 221 30 of of IN cord-005646-xhx9pzhj 221 31 adjuvant adjuvant NN cord-005646-xhx9pzhj 221 32 inhaled inhale VBN cord-005646-xhx9pzhj 221 33 anesthetics anesthetic NNS cord-005646-xhx9pzhj 221 34 ~. ~. . cord-005646-xhx9pzhj 221 35 Methods method NNS cord-005646-xhx9pzhj 221 36 . . . cord-005646-xhx9pzhj 222 1 With with IN cord-005646-xhx9pzhj 222 2 approval approval NN cord-005646-xhx9pzhj 222 3 of of IN cord-005646-xhx9pzhj 222 4 our -PRON- PRP$ cord-005646-xhx9pzhj 222 5 Committee Committee NNP cord-005646-xhx9pzhj 222 6 on on IN cord-005646-xhx9pzhj 222 7 Clinical Clinical NNP cord-005646-xhx9pzhj 222 8 Investigations Investigations NNP cord-005646-xhx9pzhj 222 9 ( ( -LRB- cord-005646-xhx9pzhj 222 10 IRB IRB NNP cord-005646-xhx9pzhj 222 11 ) ) -RRB- cord-005646-xhx9pzhj 222 12 , , , cord-005646-xhx9pzhj 222 13 Roe Roe NNP cord-005646-xhx9pzhj 222 14 1.2 1.2 CD cord-005646-xhx9pzhj 222 15 mg mg NNP cord-005646-xhx9pzhj 222 16 / / SYM cord-005646-xhx9pzhj 222 17 kg kg NNS cord-005646-xhx9pzhj 222 18 was be VBD cord-005646-xhx9pzhj 222 19 administered administer VBN cord-005646-xhx9pzhj 222 20 to to IN cord-005646-xhx9pzhj 222 21 15 15 CD cord-005646-xhx9pzhj 222 22 ASA ASA NNP cord-005646-xhx9pzhj 222 23 III III NNP cord-005646-xhx9pzhj 222 24 / / SYM cord-005646-xhx9pzhj 222 25 IV IV NNP cord-005646-xhx9pzhj 222 26 pediatric pediatric JJ cord-005646-xhx9pzhj 222 27 intensive intensive JJ cord-005646-xhx9pzhj 222 28 care care NN cord-005646-xhx9pzhj 222 29 patients patient NNS cord-005646-xhx9pzhj 222 30 ( ( -LRB- cord-005646-xhx9pzhj 222 31 age age NN cord-005646-xhx9pzhj 222 32 40 40 CD cord-005646-xhx9pzhj 222 33 days day NNS cord-005646-xhx9pzhj 222 34 to to IN cord-005646-xhx9pzhj 222 35 23 23 CD cord-005646-xhx9pzhj 222 36 months month NNS cord-005646-xhx9pzhj 222 37 ; ; : cord-005646-xhx9pzhj 222 38 M m NN cord-005646-xhx9pzhj 222 39 : : : cord-005646-xhx9pzhj 222 40 F=8:7 F=8:7 NNP cord-005646-xhx9pzhj 222 41 ) ) -RRB- cord-005646-xhx9pzhj 223 1 on on IN cord-005646-xhx9pzhj 223 2 intravenous intravenous JJ cord-005646-xhx9pzhj 223 3 sedation sedation NN cord-005646-xhx9pzhj 223 4 . . . cord-005646-xhx9pzhj 224 1 The the DT cord-005646-xhx9pzhj 224 2 time time NN cord-005646-xhx9pzhj 224 3 to to TO cord-005646-xhx9pzhj 224 4 reach reach VB cord-005646-xhx9pzhj 224 5 25 25 CD cord-005646-xhx9pzhj 224 6 % % NN cord-005646-xhx9pzhj 224 7 a a DT cord-005646-xhx9pzhj 224 8 ~ ~ CD cord-005646-xhx9pzhj 224 9 d d NN cord-005646-xhx9pzhj 224 10 10 10 CD cord-005646-xhx9pzhj 224 11 % % NN cord-005646-xhx9pzhj 224 12 of of IN cord-005646-xhx9pzhj 224 13 b b NNP cord-005646-xhx9pzhj 224 14 ~ ~ CD cord-005646-xhx9pzhj 224 15 elinc elinc NNP cord-005646-xhx9pzhj 224 16 tetanie tetanie NNP cord-005646-xhx9pzhj 224 17 stimulus stimulus NNP cord-005646-xhx9pzhj 224 18 response response NN cord-005646-xhx9pzhj 224 19 was be VBD cord-005646-xhx9pzhj 224 20 recorded record VBN cord-005646-xhx9pzhj 224 21 using use VBG cord-005646-xhx9pzhj 224 22 a a DT cord-005646-xhx9pzhj 224 23 R.elaxogra'ph r.elaxogra'ph CD cord-005646-xhx9pzhj 224 24 / / SYM cord-005646-xhx9pzhj 224 25 qMT-100 qMT-100 NNS cord-005646-xhx9pzhj 224 26 nerve nerve NN cord-005646-xhx9pzhj 224 27 stimulator stimulator NN cord-005646-xhx9pzhj 224 28 / / SYM cord-005646-xhx9pzhj 224 29 recorder recorder NN cord-005646-xhx9pzhj 224 30 ( ( -LRB- cord-005646-xhx9pzhj 224 31 Datex Datex NNP cord-005646-xhx9pzhj 224 32 , , , cord-005646-xhx9pzhj 224 33 Helsiaki Helsiaki NNP cord-005646-xhx9pzhj 224 34 ) ) -RRB- cord-005646-xhx9pzhj 224 35 . . . cord-005646-xhx9pzhj 225 1 Depth depth NN cord-005646-xhx9pzhj 225 2 of of IN cord-005646-xhx9pzhj 225 3 clinical clinical JJ cord-005646-xhx9pzhj 225 4 relaxation relaxation NN cord-005646-xhx9pzhj 225 5 at at IN cord-005646-xhx9pzhj 225 6 the the DT cord-005646-xhx9pzhj 225 7 25 25 CD cord-005646-xhx9pzhj 225 8 % % NN cord-005646-xhx9pzhj 225 9 level level NN cord-005646-xhx9pzhj 225 10 was be VBD cord-005646-xhx9pzhj 225 11 recorded record VBN cord-005646-xhx9pzhj 225 12 . . . cord-005646-xhx9pzhj 226 1 Results result NNS cord-005646-xhx9pzhj 226 2 . . . cord-005646-xhx9pzhj 227 1 The the DT cord-005646-xhx9pzhj 227 2 time time NN cord-005646-xhx9pzhj 227 3 from from IN cord-005646-xhx9pzhj 227 4 rapid rapid JJ cord-005646-xhx9pzhj 227 5 bolus bolus NN cord-005646-xhx9pzhj 227 6 to to IN cord-005646-xhx9pzhj 227 7 25 25 CD cord-005646-xhx9pzhj 227 8 % % NN cord-005646-xhx9pzhj 227 9 was be VBD cord-005646-xhx9pzhj 227 10 25.4 25.4 CD cord-005646-xhx9pzhj 227 11 + + SYM cord-005646-xhx9pzhj 227 12 12.6 12.6 CD cord-005646-xhx9pzhj 227 13 see see VBP cord-005646-xhx9pzhj 227 14 with with IN cord-005646-xhx9pzhj 227 15 a a DT cord-005646-xhx9pzhj 227 16 range range NN cord-005646-xhx9pzhj 227 17 of of IN cord-005646-xhx9pzhj 227 18 10 10 CD cord-005646-xhx9pzhj 227 19 - - SYM cord-005646-xhx9pzhj 227 20 50 50 CD cord-005646-xhx9pzhj 227 21 see see VBP cord-005646-xhx9pzhj 227 22 ; ; : cord-005646-xhx9pzhj 227 23 and and CC cord-005646-xhx9pzhj 227 24 to to IN cord-005646-xhx9pzhj 227 25 10 10 CD cord-005646-xhx9pzhj 227 26 % % NN cord-005646-xhx9pzhj 227 27 was be VBD cord-005646-xhx9pzhj 227 28 30.1 30.1 CD cord-005646-xhx9pzhj 227 29 + + SYM cord-005646-xhx9pzhj 227 30 17.6 17.6 CD cord-005646-xhx9pzhj 227 31 see see VBP cord-005646-xhx9pzhj 227 32 , , , cord-005646-xhx9pzhj 227 33 with with IN cord-005646-xhx9pzhj 227 34 a a DT cord-005646-xhx9pzhj 227 35 range range NN cord-005646-xhx9pzhj 227 36 of of IN cord-005646-xhx9pzhj 227 37 10 10 CD cord-005646-xhx9pzhj 227 38 - - SYM cord-005646-xhx9pzhj 227 39 69 69 CD cord-005646-xhx9pzhj 227 40 see see NN cord-005646-xhx9pzhj 227 41 . . . cord-005646-xhx9pzhj 228 1 At at IN cord-005646-xhx9pzhj 228 2 the the DT cord-005646-xhx9pzhj 228 3 25 25 CD cord-005646-xhx9pzhj 228 4 % % NN cord-005646-xhx9pzhj 228 5 level level NN cord-005646-xhx9pzhj 228 6 , , , cord-005646-xhx9pzhj 228 7 excellent excellent JJ cord-005646-xhx9pzhj 228 8 clinical clinical JJ cord-005646-xhx9pzhj 228 9 relaxation relaxation NN cord-005646-xhx9pzhj 228 10 was be VBD cord-005646-xhx9pzhj 228 11 seen see VBN cord-005646-xhx9pzhj 228 12 . . . cord-005646-xhx9pzhj 229 1 Conduslon Conduslon NNP cord-005646-xhx9pzhj 229 2 . . . cord-005646-xhx9pzhj 230 1 In in IN cord-005646-xhx9pzhj 230 2 critically critically RB cord-005646-xhx9pzhj 230 3 ill ill JJ cord-005646-xhx9pzhj 230 4 children child NNS cord-005646-xhx9pzhj 230 5 , , , cord-005646-xhx9pzhj 230 6 use use NN cord-005646-xhx9pzhj 230 7 of of IN cord-005646-xhx9pzhj 230 8 Roe Roe NNP cord-005646-xhx9pzhj 230 9 at at IN cord-005646-xhx9pzhj 230 10 1.2 1.2 CD cord-005646-xhx9pzhj 230 11 mg mg NNP cord-005646-xhx9pzhj 230 12 / / SYM cord-005646-xhx9pzhj 230 13 kg kg NNP cord-005646-xhx9pzhj 230 14 produces produce VBZ cord-005646-xhx9pzhj 230 15 rapid rapid JJ cord-005646-xhx9pzhj 230 16 onset onset NN cord-005646-xhx9pzhj 230 17 of of IN cord-005646-xhx9pzhj 230 18 neuromuscular neuromuscular JJ cord-005646-xhx9pzhj 230 19 blockade blockade NN cord-005646-xhx9pzhj 230 20 and and CC cord-005646-xhx9pzhj 230 21 excellent excellent JJ cord-005646-xhx9pzhj 230 22 clinical clinical JJ cord-005646-xhx9pzhj 230 23 relaxation relaxation NN cord-005646-xhx9pzhj 230 24 , , , cord-005646-xhx9pzhj 230 25 such such JJ cord-005646-xhx9pzhj 230 26 that that IN cord-005646-xhx9pzhj 230 27 Roe Roe NNP cord-005646-xhx9pzhj 230 28 should should MD cord-005646-xhx9pzhj 230 29 be be VB cord-005646-xhx9pzhj 230 30 considered consider VBN cord-005646-xhx9pzhj 230 31 for for IN cord-005646-xhx9pzhj 230 32 rapid rapid JJ cord-005646-xhx9pzhj 230 33 sequence sequence NN cord-005646-xhx9pzhj 230 34 intubation intubation NN cord-005646-xhx9pzhj 230 35 . . . cord-005646-xhx9pzhj 231 1 Int Int NNP cord-005646-xhx9pzhj 231 2 Anesth Anesth NNP cord-005646-xhx9pzhj 231 3 Clin Clin NNP cord-005646-xhx9pzhj 231 4 . . . cord-005646-xhx9pzhj 232 1 1995;33(1):39 1995;33(1):39 CD cord-005646-xhx9pzhj 232 2 - - SYM cord-005646-xhx9pzhj 232 3 60 60 CD cord-005646-xhx9pzhj 232 4 . . . cord-005646-xhx9pzhj 233 1 Anesthesiology Anesthesiology NNP cord-005646-xhx9pzhj 233 2 . . . cord-005646-xhx9pzhj 233 3 1994;81 1994;81 CD cord-005646-xhx9pzhj 233 4 ( ( -LRB- cord-005646-xhx9pzhj 233 5 5 5 CD cord-005646-xhx9pzhj 233 6 ) ) -RRB- cord-005646-xhx9pzhj 233 7 Computed compute VBN cord-005646-xhx9pzhj 233 8 tomography tomography NN cord-005646-xhx9pzhj 233 9 of of IN cord-005646-xhx9pzhj 233 10 the the DT cord-005646-xhx9pzhj 233 11 chest chest NN cord-005646-xhx9pzhj 233 12 ( ( -LRB- cord-005646-xhx9pzhj 233 13 CT CT NNP cord-005646-xhx9pzhj 233 14 ) ) -RRB- cord-005646-xhx9pzhj 233 15 in in IN cord-005646-xhx9pzhj 233 16 mechanically mechanically RB cord-005646-xhx9pzhj 233 17 ventilated ventilate VBN cord-005646-xhx9pzhj 233 18 adults adult NNS cord-005646-xhx9pzhj 233 19 can can MD cord-005646-xhx9pzhj 233 20 detect detect VB cord-005646-xhx9pzhj 233 21 intrathoracic intrathoracic JJ cord-005646-xhx9pzhj 233 22 pathology pathology NN cord-005646-xhx9pzhj 233 23 not not RB cord-005646-xhx9pzhj 233 24 appreciated appreciate VBN cord-005646-xhx9pzhj 233 25 on on IN cord-005646-xhx9pzhj 233 26 chest chest NN cord-005646-xhx9pzhj 233 27 radiographs radiograph NNS cord-005646-xhx9pzhj 233 28 ( ( -LRB- cord-005646-xhx9pzhj 233 29 CXR CXR NNP cord-005646-xhx9pzhj 233 30 ) ) -RRB- cord-005646-xhx9pzhj 233 31 and and CC cord-005646-xhx9pzhj 233 32 influence influence VB cord-005646-xhx9pzhj 233 33 intensive intensive JJ cord-005646-xhx9pzhj 233 34 care care NN cord-005646-xhx9pzhj 233 35 management management NN cord-005646-xhx9pzhj 233 36 . . . cord-005646-xhx9pzhj 234 1 No no DT cord-005646-xhx9pzhj 234 2 such such JJ cord-005646-xhx9pzhj 234 3 data data NN cord-005646-xhx9pzhj 234 4 exists exist VBZ cord-005646-xhx9pzhj 234 5 for for IN cord-005646-xhx9pzhj 234 6 ventilated ventilate VBN cord-005646-xhx9pzhj 234 7 children child NNS cord-005646-xhx9pzhj 234 8 . . . cord-005646-xhx9pzhj 235 1 AIMS aim VBZ cord-005646-xhx9pzhj 235 2 : : : cord-005646-xhx9pzhj 235 3 1 1 LS cord-005646-xhx9pzhj 235 4 ) ) -RRB- cord-005646-xhx9pzhj 236 1 To to TO cord-005646-xhx9pzhj 236 2 assess assess VB cord-005646-xhx9pzhj 236 3 if if IN cord-005646-xhx9pzhj 236 4 CT CT NNP cord-005646-xhx9pzhj 236 5 provides provide VBZ cord-005646-xhx9pzhj 236 6 additional additional JJ cord-005646-xhx9pzhj 236 7 information information NN cord-005646-xhx9pzhj 236 8 over over IN cord-005646-xhx9pzhj 236 9 CXR CXR NNP cord-005646-xhx9pzhj 236 10 regarding regard VBG cord-005646-xhx9pzhj 236 11 extent extent NN cord-005646-xhx9pzhj 236 12 and and CC cord-005646-xhx9pzhj 236 13 nature nature NN cord-005646-xhx9pzhj 236 14 of of IN cord-005646-xhx9pzhj 236 15 intrathoracic intrathoracic JJ cord-005646-xhx9pzhj 236 16 disease disease NN cord-005646-xhx9pzhj 236 17 in in IN cord-005646-xhx9pzhj 236 18 ventilated ventilate VBN cord-005646-xhx9pzhj 236 19 children child NNS cord-005646-xhx9pzhj 236 20 . . . cord-005646-xhx9pzhj 237 1 2 2 LS cord-005646-xhx9pzhj 237 2 ) ) -RRB- cord-005646-xhx9pzhj 238 1 To to TO cord-005646-xhx9pzhj 238 2 determine determine VB cord-005646-xhx9pzhj 238 3 whether whether IN cord-005646-xhx9pzhj 238 4 such such JJ cord-005646-xhx9pzhj 238 5 information information NN cord-005646-xhx9pzhj 238 6 alters alter VBZ cord-005646-xhx9pzhj 238 7 clinical clinical JJ cord-005646-xhx9pzhj 238 8 management management NN cord-005646-xhx9pzhj 238 9 , , , cord-005646-xhx9pzhj 238 10 INCLUSION inclusion NN cord-005646-xhx9pzhj 238 11 CRITERIA criterion NNS cord-005646-xhx9pzhj 238 12 : : : cord-005646-xhx9pzhj 238 13 10 10 CD cord-005646-xhx9pzhj 238 14 ventilated ventilate VBN cord-005646-xhx9pzhj 238 15 children child NNS cord-005646-xhx9pzhj 238 16 with with IN cord-005646-xhx9pzhj 238 17 CXR CXR NNP cord-005646-xhx9pzhj 238 18 changes change NNS cord-005646-xhx9pzhj 238 19 inconsistent inconsistent JJ cord-005646-xhx9pzhj 238 20 with with IN cord-005646-xhx9pzhj 238 21 their -PRON- PRP$ cord-005646-xhx9pzhj 238 22 respiratory respiratory JJ cord-005646-xhx9pzhj 238 23 status status NN cord-005646-xhx9pzhj 238 24 underwent undergo VBD cord-005646-xhx9pzhj 238 25 CT CT NNP cord-005646-xhx9pzhj 238 26 if if IN cord-005646-xhx9pzhj 238 27 either either CC cord-005646-xhx9pzhj 238 28 a a DT cord-005646-xhx9pzhj 238 29 ) ) -RRB- cord-005646-xhx9pzhj 238 30 PaO2 pao2 NN cord-005646-xhx9pzhj 238 31 : : : cord-005646-xhx9pzhj 239 1 FiO2 FiO2 NNP cord-005646-xhx9pzhj 239 2 ratio ratio NN cord-005646-xhx9pzhj 240 1 < < XX cord-005646-xhx9pzhj 240 2 30 30 CD cord-005646-xhx9pzhj 241 1 and/or and/or CC cord-005646-xhx9pzhj 241 2 mean mean VB cord-005646-xhx9pzhj 241 3 Paw>15 Paw>15 NNP cord-005646-xhx9pzhj 241 4 cm cm POS cord-005646-xhx9pzhj 241 5 H20 H20 NNP cord-005646-xhx9pzhj 241 6 or or CC cord-005646-xhx9pzhj 241 7 b b NN cord-005646-xhx9pzhj 242 1 ) ) -RRB- cord-005646-xhx9pzhj 242 2 there there EX cord-005646-xhx9pzhj 242 3 was be VBD cord-005646-xhx9pzhj 242 4 an an DT cord-005646-xhx9pzhj 242 5 unexplained unexplained JJ cord-005646-xhx9pzhj 242 6 increase increase NN cord-005646-xhx9pzhj 242 7 in in IN cord-005646-xhx9pzhj 242 8 ventilatory ventilatory JJ cord-005646-xhx9pzhj 242 9 requirement requirement NN cord-005646-xhx9pzhj 242 10 . . . cord-005646-xhx9pzhj 243 1 METHODS methods NN cord-005646-xhx9pzhj 243 2 : : : cord-005646-xhx9pzhj 244 1 High high JJ cord-005646-xhx9pzhj 244 2 resolution resolution NN cord-005646-xhx9pzhj 244 3 CT CT NNP cord-005646-xhx9pzhj 244 4 was be VBD cord-005646-xhx9pzhj 244 5 performed perform VBN cord-005646-xhx9pzhj 244 6 in in IN cord-005646-xhx9pzhj 244 7 3 3 CD cord-005646-xhx9pzhj 244 8 patients patient NNS cord-005646-xhx9pzhj 244 9 and and CC cord-005646-xhx9pzhj 244 10 spiral spiral JJ cord-005646-xhx9pzhj 244 11 CT CT NNP cord-005646-xhx9pzhj 244 12 in in IN cord-005646-xhx9pzhj 244 13 7 7 CD cord-005646-xhx9pzhj 244 14 patierits patierit NNS cord-005646-xhx9pzhj 244 15 , , , cord-005646-xhx9pzhj 244 16 To to TO cord-005646-xhx9pzhj 244 17 ensure ensure VB cord-005646-xhx9pzhj 244 18 minimal minimal JJ cord-005646-xhx9pzhj 244 19 transport transport NN cord-005646-xhx9pzhj 244 20 related relate VBN cord-005646-xhx9pzhj 244 21 morbidity morbidity NN cord-005646-xhx9pzhj 244 22 , , , cord-005646-xhx9pzhj 244 23 patients patient NNS cord-005646-xhx9pzhj 244 24 were be VBD cord-005646-xhx9pzhj 244 25 transferred transfer VBN cord-005646-xhx9pzhj 244 26 to to IN cord-005646-xhx9pzhj 244 27 the the DT cord-005646-xhx9pzhj 244 28 CT CT NNP cord-005646-xhx9pzhj 244 29 scanner scanner NN cord-005646-xhx9pzhj 244 30 by by IN cord-005646-xhx9pzhj 244 31 a a DT cord-005646-xhx9pzhj 244 32 specialised specialised JJ cord-005646-xhx9pzhj 244 33 mobile mobile JJ cord-005646-xhx9pzhj 244 34 intensive intensive JJ cord-005646-xhx9pzhj 244 35 care care NN cord-005646-xhx9pzhj 244 36 team team NN cord-005646-xhx9pzhj 244 37 . . . cord-005646-xhx9pzhj 245 1 RESULTS result NNS cord-005646-xhx9pzhj 245 2 : : : cord-005646-xhx9pzhj 246 1 In in IN cord-005646-xhx9pzhj 246 2 2/10 2/10 CD cord-005646-xhx9pzhj 246 3 patients patient NNS cord-005646-xhx9pzhj 246 4 CT CT NNP cord-005646-xhx9pzhj 246 5 demonstrated demonstrate VBD cord-005646-xhx9pzhj 246 6 greater great JJR cord-005646-xhx9pzhj 246 7 extent extent NN cord-005646-xhx9pzhj 246 8 of of IN cord-005646-xhx9pzhj 246 9 disease disease NN cord-005646-xhx9pzhj 246 10 than than IN cord-005646-xhx9pzhj 246 11 appreciated appreciate VBN cord-005646-xhx9pzhj 246 12 on on IN cord-005646-xhx9pzhj 246 13 CXR CXR NNP cord-005646-xhx9pzhj 246 14 but but CC cord-005646-xhx9pzhj 246 15 did do VBD cord-005646-xhx9pzhj 246 16 not not RB cord-005646-xhx9pzhj 246 17 significantly significantly RB cord-005646-xhx9pzhj 246 18 alter alter VB cord-005646-xhx9pzhj 246 19 clinical clinical JJ cord-005646-xhx9pzhj 246 20 management management NN cord-005646-xhx9pzhj 246 21 . . . cord-005646-xhx9pzhj 247 1 In in IN cord-005646-xhx9pzhj 247 2 7/10 7/10 CD cord-005646-xhx9pzhj 247 3 patients patient NNS cord-005646-xhx9pzhj 247 4 CT CT NNP cord-005646-xhx9pzhj 247 5 provided provide VBD cord-005646-xhx9pzhj 247 6 additional additional JJ cord-005646-xhx9pzhj 247 7 information information NN cord-005646-xhx9pzhj 247 8 regarding regard VBG cord-005646-xhx9pzhj 247 9 the the DT cord-005646-xhx9pzhj 247 10 nature nature NN cord-005646-xhx9pzhj 247 11 of of IN cord-005646-xhx9pzhj 247 12 disease disease NN cord-005646-xhx9pzhj 247 13 present present NN cord-005646-xhx9pzhj 247 14 , , , cord-005646-xhx9pzhj 247 15 In in IN cord-005646-xhx9pzhj 247 16 2/7 2/7 CD cord-005646-xhx9pzhj 247 17 children child NNS cord-005646-xhx9pzhj 247 18 this this DT cord-005646-xhx9pzhj 247 19 involved involve VBD cord-005646-xhx9pzhj 247 20 a a DT cord-005646-xhx9pzhj 247 21 further further JJ cord-005646-xhx9pzhj 247 22 diagnosis diagnosis NN cord-005646-xhx9pzhj 247 23 and and CC cord-005646-xhx9pzhj 247 24 in in IN cord-005646-xhx9pzhj 247 25 5/7 5/7 CD cord-005646-xhx9pzhj 247 26 children child NNS cord-005646-xhx9pzhj 247 27 the the DT cord-005646-xhx9pzhj 247 28 exclusion exclusion NN cord-005646-xhx9pzhj 247 29 of of IN cord-005646-xhx9pzhj 247 30 a a DT cord-005646-xhx9pzhj 247 31 suspected suspect VBN cord-005646-xhx9pzhj 247 32 pathology pathology NN cord-005646-xhx9pzhj 247 33 . . . cord-005646-xhx9pzhj 248 1 New new JJ cord-005646-xhx9pzhj 248 2 information information NN cord-005646-xhx9pzhj 248 3 led lead VBD cord-005646-xhx9pzhj 248 4 to to IN cord-005646-xhx9pzhj 248 5 a a DT cord-005646-xhx9pzhj 248 6 positive positive JJ cord-005646-xhx9pzhj 248 7 therapeutic therapeutic JJ cord-005646-xhx9pzhj 248 8 intervention intervention NN cord-005646-xhx9pzhj 248 9 in in IN cord-005646-xhx9pzhj 248 10 2 2 CD cord-005646-xhx9pzhj 248 11 children child NNS cord-005646-xhx9pzhj 248 12 , , , cord-005646-xhx9pzhj 248 13 prevented prevent VBD cord-005646-xhx9pzhj 248 14 inappropriate inappropriate JJ cord-005646-xhx9pzhj 248 15 manoeuvres manoeuvre NNS cord-005646-xhx9pzhj 248 16 in in IN cord-005646-xhx9pzhj 248 17 3 3 CD cord-005646-xhx9pzhj 248 18 , , , cord-005646-xhx9pzhj 248 19 and and CC cord-005646-xhx9pzhj 248 20 had have VBD cord-005646-xhx9pzhj 248 21 no no DT cord-005646-xhx9pzhj 248 22 significant significant JJ cord-005646-xhx9pzhj 248 23 effect effect NN cord-005646-xhx9pzhj 248 24 on on IN cord-005646-xhx9pzhj 248 25 acute acute JJ cord-005646-xhx9pzhj 248 26 management management NN cord-005646-xhx9pzhj 248 27 in in IN cord-005646-xhx9pzhj 248 28 2 2 CD cord-005646-xhx9pzhj 248 29 children child NNS cord-005646-xhx9pzhj 248 30 . . . cord-005646-xhx9pzhj 249 1 CONCLUSIONS conclusion NNS cord-005646-xhx9pzhj 249 2 : : : cord-005646-xhx9pzhj 250 1 Initial initial JJ cord-005646-xhx9pzhj 250 2 data data NN cord-005646-xhx9pzhj 250 3 suggests suggest VBZ cord-005646-xhx9pzhj 250 4 that that IN cord-005646-xhx9pzhj 250 5 in in IN cord-005646-xhx9pzhj 250 6 a a DT cord-005646-xhx9pzhj 250 7 selected select VBN cord-005646-xhx9pzhj 250 8 group group NN cord-005646-xhx9pzhj 250 9 of of IN cord-005646-xhx9pzhj 250 10 mechanically mechanically RB cord-005646-xhx9pzhj 250 11 ventilated ventilate VBN cord-005646-xhx9pzhj 250 12 children child NNS cord-005646-xhx9pzhj 250 13 chest chest NN cord-005646-xhx9pzhj 250 14 CT CT NNP cord-005646-xhx9pzhj 250 15 can can MD cord-005646-xhx9pzhj 250 16 add add VB cord-005646-xhx9pzhj 250 17 to to IN cord-005646-xhx9pzhj 250 18 the the DT cord-005646-xhx9pzhj 250 19 sensitivity sensitivity NN cord-005646-xhx9pzhj 250 20 and and CC cord-005646-xhx9pzhj 250 21 specificity specificity NN cord-005646-xhx9pzhj 250 22 of of IN cord-005646-xhx9pzhj 250 23 intrathoracic intrathoracic JJ cord-005646-xhx9pzhj 250 24 diagnosis diagnosis NN cord-005646-xhx9pzhj 250 25 provided provide VBN cord-005646-xhx9pzhj 250 26 by by IN cord-005646-xhx9pzhj 250 27 the the DT cord-005646-xhx9pzhj 250 28 chest chest NN cord-005646-xhx9pzhj 250 29 radiograph radiograph NN cord-005646-xhx9pzhj 250 30 and and CC cord-005646-xhx9pzhj 250 31 directly directly RB cord-005646-xhx9pzhj 250 32 influence influence VB cord-005646-xhx9pzhj 250 33 acute acute JJ cord-005646-xhx9pzhj 250 34 management management NN cord-005646-xhx9pzhj 250 35 . . . cord-005646-xhx9pzhj 251 1 Case case NN cord-005646-xhx9pzhj 251 2 selection selection NN cord-005646-xhx9pzhj 251 3 criteria criterion NNS cord-005646-xhx9pzhj 251 4 and and CC cord-005646-xhx9pzhj 251 5 choice choice NN cord-005646-xhx9pzhj 251 6 of of IN cord-005646-xhx9pzhj 251 7 the the DT cord-005646-xhx9pzhj 251 8 most most RBS cord-005646-xhx9pzhj 251 9 appropriate appropriate JJ cord-005646-xhx9pzhj 251 10 protocol protocol NN cord-005646-xhx9pzhj 251 11 requires require VBZ cord-005646-xhx9pzhj 251 12 further further JJ cord-005646-xhx9pzhj 251 13 study study NN cord-005646-xhx9pzhj 251 14 . . . cord-005646-xhx9pzhj 251 15 _SP cord-005646-xhx9pzhj 252 1 Pressure pressure NN cord-005646-xhx9pzhj 252 2 control control NN cord-005646-xhx9pzhj 252 3 ventilation ventilation NN cord-005646-xhx9pzhj 252 4 ( ( -LRB- cord-005646-xhx9pzhj 252 5 PCV pcv NN cord-005646-xhx9pzhj 252 6 ) ) -RRB- cord-005646-xhx9pzhj 252 7 utilizes utilize VBZ cord-005646-xhx9pzhj 252 8 a a DT cord-005646-xhx9pzhj 252 9 decelerating decelerate VBG cord-005646-xhx9pzhj 252 10 flow flow NN cord-005646-xhx9pzhj 252 11 pattern pattern NN cord-005646-xhx9pzhj 252 12 which which WDT cord-005646-xhx9pzhj 252 13 may may MD cord-005646-xhx9pzhj 252 14 improve improve VB cord-005646-xhx9pzhj 252 15 gas gas NN cord-005646-xhx9pzhj 252 16 distribution distribution NN cord-005646-xhx9pzhj 252 17 and and CC cord-005646-xhx9pzhj 252 18 lead lead NN cord-005646-xhx9pzhj 252 19 to to IN cord-005646-xhx9pzhj 252 20 alveolar alveolar NN cord-005646-xhx9pzhj 252 21 recruitment recruitment NN cord-005646-xhx9pzhj 252 22 . . . cord-005646-xhx9pzhj 253 1 In in IN cord-005646-xhx9pzhj 253 2 contrast contrast NN cord-005646-xhx9pzhj 253 3 , , , cord-005646-xhx9pzhj 253 4 volume volume NN cord-005646-xhx9pzhj 253 5 control control NN cord-005646-xhx9pzhj 253 6 ventilation ventilation NN cord-005646-xhx9pzhj 253 7 ( ( -LRB- cord-005646-xhx9pzhj 253 8 VCV VCV NNP cord-005646-xhx9pzhj 253 9 ) ) -RRB- cord-005646-xhx9pzhj 253 10 employs employ VBZ cord-005646-xhx9pzhj 253 11 a a DT cord-005646-xhx9pzhj 253 12 constant constant JJ cord-005646-xhx9pzhj 253 13 flow flow NN cord-005646-xhx9pzhj 253 14 . . . cord-005646-xhx9pzhj 254 1 In in IN cord-005646-xhx9pzhj 254 2 children child NNS cord-005646-xhx9pzhj 254 3 , , , cord-005646-xhx9pzhj 254 4 the the DT cord-005646-xhx9pzhj 254 5 effects effect NNS cord-005646-xhx9pzhj 254 6 of of IN cord-005646-xhx9pzhj 254 7 PCV pcv NN cord-005646-xhx9pzhj 254 8 as as IN cord-005646-xhx9pzhj 254 9 compared compare VBN cord-005646-xhx9pzhj 254 10 to to IN cord-005646-xhx9pzhj 254 11 VCV VCV NNP cord-005646-xhx9pzhj 254 12 are be VBP cord-005646-xhx9pzhj 254 13 unclear unclear JJ cord-005646-xhx9pzhj 254 14 . . . cord-005646-xhx9pzhj 255 1 The the DT cord-005646-xhx9pzhj 255 2 purpose purpose NN cord-005646-xhx9pzhj 255 3 of of IN cord-005646-xhx9pzhj 255 4 this this DT cord-005646-xhx9pzhj 255 5 study study NN cord-005646-xhx9pzhj 255 6 was be VBD cord-005646-xhx9pzhj 255 7 to to TO cord-005646-xhx9pzhj 255 8 determine determine VB cord-005646-xhx9pzhj 255 9 how how WRB cord-005646-xhx9pzhj 255 10 these these DT cord-005646-xhx9pzhj 255 11 two two CD cord-005646-xhx9pzhj 255 12 modes mode NNS cord-005646-xhx9pzhj 255 13 compare compare VBP cord-005646-xhx9pzhj 255 14 in in IN cord-005646-xhx9pzhj 255 15 terms term NNS cord-005646-xhx9pzhj 255 16 of of IN cord-005646-xhx9pzhj 255 17 dynamic dynamic JJ cord-005646-xhx9pzhj 255 18 compliance compliance NN cord-005646-xhx9pzhj 255 19 ( ( -LRB- cord-005646-xhx9pzhj 255 20 Cdyn Cdyn NNP cord-005646-xhx9pzhj 255 21 ) ) -RRB- cord-005646-xhx9pzhj 255 22 . . . cord-005646-xhx9pzhj 256 1 peak peak NNP cord-005646-xhx9pzhj 256 2 iaspiratory iaspiratory NNP cord-005646-xhx9pzhj 256 3 pressure pressure NN cord-005646-xhx9pzhj 256 4 ( ( -LRB- cord-005646-xhx9pzhj 256 5 PIP PIP NNP cord-005646-xhx9pzhj 256 6 ) ) -RRB- cord-005646-xhx9pzhj 256 7 , , , cord-005646-xhx9pzhj 256 8 and and CC cord-005646-xhx9pzhj 256 9 mean mean VB cord-005646-xhx9pzhj 256 10 airway airway NN cord-005646-xhx9pzhj 256 11 pressure pressure NN cord-005646-xhx9pzhj 256 12 ( ( -LRB- cord-005646-xhx9pzhj 256 13 Paw Paw NNP cord-005646-xhx9pzhj 256 14 ) ) -RRB- cord-005646-xhx9pzhj 256 15 at at IN cord-005646-xhx9pzhj 256 16 equivalent equivalent JJ cord-005646-xhx9pzhj 256 17 minute minute NN cord-005646-xhx9pzhj 256 18 ventilation ventilation NN cord-005646-xhx9pzhj 256 19 . . . cord-005646-xhx9pzhj 257 1 Methods method NNS cord-005646-xhx9pzhj 257 2 : : : cord-005646-xhx9pzhj 257 3 Sixteen sixteen CD cord-005646-xhx9pzhj 257 4 infants infant NNS cord-005646-xhx9pzhj 257 5 and and CC cord-005646-xhx9pzhj 257 6 pediatric pediatric JJ cord-005646-xhx9pzhj 257 7 patients patient NNS cord-005646-xhx9pzhj 257 8 ranging range VBG cord-005646-xhx9pzhj 257 9 in in IN cord-005646-xhx9pzhj 257 10 age age NN cord-005646-xhx9pzhj 257 11 from from IN cord-005646-xhx9pzhj 257 12 1 1 CD cord-005646-xhx9pzhj 257 13 day day NN cord-005646-xhx9pzhj 257 14 to to IN cord-005646-xhx9pzhj 257 15 13 13 CD cord-005646-xhx9pzhj 257 16 years year NNS cord-005646-xhx9pzhj 257 17 were be VBD cord-005646-xhx9pzhj 257 18 studied study VBN cord-005646-xhx9pzhj 257 19 . . . cord-005646-xhx9pzhj 258 1 Diagnoses diagnosis NNS cord-005646-xhx9pzhj 258 2 included include VBD cord-005646-xhx9pzhj 258 3 ARDS ARDS NNP cord-005646-xhx9pzhj 258 4 ( ( -LRB- cord-005646-xhx9pzhj 258 5 6 6 CD cord-005646-xhx9pzhj 258 6 ) ) -RRB- cord-005646-xhx9pzhj 258 7 , , , cord-005646-xhx9pzhj 258 8 postoperative postoperative JJ cord-005646-xhx9pzhj 258 9 cardiac cardiac JJ cord-005646-xhx9pzhj 258 10 surgery surgery NN cord-005646-xhx9pzhj 258 11 ( ( -LRB- cord-005646-xhx9pzhj 258 12 7 7 CD cord-005646-xhx9pzhj 258 13 ) ) -RRB- cord-005646-xhx9pzhj 258 14 , , , cord-005646-xhx9pzhj 258 15 head head NN cord-005646-xhx9pzhj 258 16 trauma trauma NN cord-005646-xhx9pzhj 258 17 ( ( -LRB- cord-005646-xhx9pzhj 258 18 1 1 CD cord-005646-xhx9pzhj 258 19 ) ) -RRB- cord-005646-xhx9pzhj 258 20 , , , cord-005646-xhx9pzhj 258 21 and and CC cord-005646-xhx9pzhj 258 22 resfrictive resfrictive JJ cord-005646-xhx9pzhj 258 23 lung lung NN cord-005646-xhx9pzhj 258 24 disease disease NN cord-005646-xhx9pzhj 258 25 ( ( -LRB- cord-005646-xhx9pzhj 258 26 2 2 CD cord-005646-xhx9pzhj 258 27 ) ) -RRB- cord-005646-xhx9pzhj 258 28 . . . cord-005646-xhx9pzhj 259 1 Patients patient NNS cord-005646-xhx9pzhj 259 2 were be VBD cord-005646-xhx9pzhj 259 3 randomized randomize VBN cord-005646-xhx9pzhj 259 4 to to IN cord-005646-xhx9pzhj 259 5 PCV PCV NNP cord-005646-xhx9pzhj 259 6 ( ( -LRB- cord-005646-xhx9pzhj 259 7 9 9 CD cord-005646-xhx9pzhj 259 8 ) ) -RRB- cord-005646-xhx9pzhj 259 9 or or CC cord-005646-xhx9pzhj 259 10 VCV VCV NNP cord-005646-xhx9pzhj 259 11 ( ( -LRB- cord-005646-xhx9pzhj 259 12 7 7 CD cord-005646-xhx9pzhj 259 13 ) ) -RRB- cord-005646-xhx9pzhj 259 14 . . . cord-005646-xhx9pzhj 260 1 Initial initial JJ cord-005646-xhx9pzhj 260 2 measurements measurement NNS cord-005646-xhx9pzhj 260 3 of of IN cord-005646-xhx9pzhj 260 4 gas gas NN cord-005646-xhx9pzhj 260 5 exchange exchange NN cord-005646-xhx9pzhj 260 6 ( ( -LRB- cord-005646-xhx9pzhj 260 7 ABG ABG NNP cord-005646-xhx9pzhj 260 8 's 's POS cord-005646-xhx9pzhj 260 9 ) ) -RRB- cord-005646-xhx9pzhj 260 10 and and CC cord-005646-xhx9pzhj 260 11 respiratory respiratory JJ cord-005646-xhx9pzhj 260 12 mechanics mechanic NNS cord-005646-xhx9pzhj 260 13 ( ( -LRB- cord-005646-xhx9pzhj 260 14 Ventrak Ventrak NNPS cord-005646-xhx9pzhj 260 15 , , , cord-005646-xhx9pzhj 260 16 Novametrix Novametrix NNP cord-005646-xhx9pzhj 260 17 Medical Medical NNP cord-005646-xhx9pzhj 260 18 Systems Systems NNPS cord-005646-xhx9pzhj 260 19 ) ) -RRB- cord-005646-xhx9pzhj 260 20 were be VBD cord-005646-xhx9pzhj 260 21 obtained obtain VBN cord-005646-xhx9pzhj 260 22 after after IN cord-005646-xhx9pzhj 260 23 a a DT cord-005646-xhx9pzhj 260 24 20 20 CD cord-005646-xhx9pzhj 260 25 minute minute NN cord-005646-xhx9pzhj 260 26 stabilizadon stabilizadon NN cord-005646-xhx9pzhj 260 27 period period NN cord-005646-xhx9pzhj 260 28 . . . cord-005646-xhx9pzhj 261 1 Respiratory respiratory JJ cord-005646-xhx9pzhj 261 2 mechanics mechanic NNS cord-005646-xhx9pzhj 261 3 included include VBD cord-005646-xhx9pzhj 261 4 PIP PIP NNP cord-005646-xhx9pzhj 261 5 , , , cord-005646-xhx9pzhj 261 6 PEEP PEEP NNP cord-005646-xhx9pzhj 261 7 , , , cord-005646-xhx9pzhj 261 8 Paw Paw NNP cord-005646-xhx9pzhj 261 9 , , , cord-005646-xhx9pzhj 261 10 delivered deliver VBD cord-005646-xhx9pzhj 261 11 tidal tidal JJ cord-005646-xhx9pzhj 261 12 volume volume NN cord-005646-xhx9pzhj 261 13 , , , cord-005646-xhx9pzhj 261 14 and and CC cord-005646-xhx9pzhj 261 15 Cdyn Cdyn NNP cord-005646-xhx9pzhj 261 16 ( ( -LRB- cord-005646-xhx9pzhj 261 17 Avolume Avolume NNP cord-005646-xhx9pzhj 261 18 / / SYM cord-005646-xhx9pzhj 261 19 Apressure Apressure NNP cord-005646-xhx9pzhj 261 20 ) ) -RRB- cord-005646-xhx9pzhj 261 21 . . . cord-005646-xhx9pzhj 262 1 The the DT cord-005646-xhx9pzhj 262 2 patients patient NNS cord-005646-xhx9pzhj 262 3 were be VBD cord-005646-xhx9pzhj 262 4 then then RB cord-005646-xhx9pzhj 262 5 crossed cross VBN cord-005646-xhx9pzhj 262 6 over over RP cord-005646-xhx9pzhj 262 7 to to IN cord-005646-xhx9pzhj 262 8 the the DT cord-005646-xhx9pzhj 262 9 alternate alternate JJ cord-005646-xhx9pzhj 262 10 mode mode NN cord-005646-xhx9pzhj 262 11 of of IN cord-005646-xhx9pzhj 262 12 ventilation ventilation NN cord-005646-xhx9pzhj 262 13 holding holding NN cord-005646-xhx9pzhj 262 14 delivered deliver VBD cord-005646-xhx9pzhj 262 15 tidal tidal JJ cord-005646-xhx9pzhj 262 16 volume volume NN cord-005646-xhx9pzhj 262 17 , , , cord-005646-xhx9pzhj 262 18 PEEP peep NN cord-005646-xhx9pzhj 262 19 , , , cord-005646-xhx9pzhj 262 20 inspiratory inspiratory JJ cord-005646-xhx9pzhj 262 21 time time NN cord-005646-xhx9pzhj 262 22 , , , cord-005646-xhx9pzhj 262 23 minute minute NN cord-005646-xhx9pzhj 262 24 ventilation ventilation NN cord-005646-xhx9pzhj 262 25 , , , cord-005646-xhx9pzhj 262 26 and and CC cord-005646-xhx9pzhj 262 27 FiO2 FiO2 NNS cord-005646-xhx9pzhj 262 28 constant constant JJ cord-005646-xhx9pzhj 262 29 . . . cord-005646-xhx9pzhj 263 1 Data datum NNS cord-005646-xhx9pzhj 263 2 were be VBD cord-005646-xhx9pzhj 263 3 collected collect VBN cord-005646-xhx9pzhj 263 4 after after IN cord-005646-xhx9pzhj 263 5 20 20 CD cord-005646-xhx9pzhj 263 6 minutes minute NNS cord-005646-xhx9pzhj 263 7 , , , cord-005646-xhx9pzhj 263 8 In in IN cord-005646-xhx9pzhj 263 9 each each DT cord-005646-xhx9pzhj 263 10 mode mode NN cord-005646-xhx9pzhj 263 11 the the DT cord-005646-xhx9pzhj 263 12 absence absence NN cord-005646-xhx9pzhj 263 13 of of IN cord-005646-xhx9pzhj 263 14 intrinsic intrinsic JJ cord-005646-xhx9pzhj 263 15 PEEP PEEP NNP cord-005646-xhx9pzhj 263 16 was be VBD cord-005646-xhx9pzhj 263 17 confirmed confirm VBN cord-005646-xhx9pzhj 263 18 . . . cord-005646-xhx9pzhj 264 1 To to TO cord-005646-xhx9pzhj 264 2 assure assure VB cord-005646-xhx9pzhj 264 3 that that IN cord-005646-xhx9pzhj 264 4 the the DT cord-005646-xhx9pzhj 264 5 measurements measurement NNS cord-005646-xhx9pzhj 264 6 were be VBD cord-005646-xhx9pzhj 264 7 not not RB cord-005646-xhx9pzhj 264 8 affected affect VBN cord-005646-xhx9pzhj 264 9 by by IN cord-005646-xhx9pzhj 264 10 changes change NNS cord-005646-xhx9pzhj 264 11 in in IN cord-005646-xhx9pzhj 264 12 clinical clinical JJ cord-005646-xhx9pzhj 264 13 status status NN cord-005646-xhx9pzhj 264 14 , , , cord-005646-xhx9pzhj 264 15 the the DT cord-005646-xhx9pzhj 264 16 patients patient NNS cord-005646-xhx9pzhj 264 17 were be VBD cord-005646-xhx9pzhj 264 18 returned return VBN cord-005646-xhx9pzhj 264 19 to to IN cord-005646-xhx9pzhj 264 20 the the DT cord-005646-xhx9pzhj 264 21 initial initial JJ cord-005646-xhx9pzhj 264 22 mode mode NN cord-005646-xhx9pzhj 264 23 of of IN cord-005646-xhx9pzhj 264 24 ventilation ventilation NN cord-005646-xhx9pzhj 264 25 and and CC cord-005646-xhx9pzhj 264 26 measurements measurement NNS cord-005646-xhx9pzhj 264 27 repeated repeat VBN cord-005646-xhx9pzhj 264 28 ( ( -LRB- cord-005646-xhx9pzhj 264 29 Final Final NNP cord-005646-xhx9pzhj 264 30 ) ) -RRB- cord-005646-xhx9pzhj 264 31 . . . cord-005646-xhx9pzhj 265 1 Patients patient NNS cord-005646-xhx9pzhj 265 2 were be VBD cord-005646-xhx9pzhj 265 3 ventilated ventilate VBN cord-005646-xhx9pzhj 265 4 with with IN cord-005646-xhx9pzhj 265 5 a a DT cord-005646-xhx9pzhj 265 6 Siemens Siemens NNP cord-005646-xhx9pzhj 265 7 900C 900C NNP cord-005646-xhx9pzhj 265 8 or or CC cord-005646-xhx9pzhj 265 9 SV300 SV300 NNP cord-005646-xhx9pzhj 265 10 . . . cord-005646-xhx9pzhj 266 1 Reselts Reselts NNP cord-005646-xhx9pzhj 266 2 : : : cord-005646-xhx9pzhj 267 1 Data datum NNS cord-005646-xhx9pzhj 267 2 were be VBD cord-005646-xhx9pzhj 267 3 analyzed analyze VBN cord-005646-xhx9pzhj 267 4 using use VBG cord-005646-xhx9pzhj 267 5 2-way 2-way JJ cord-005646-xhx9pzhj 267 6 analysis analysis NN cord-005646-xhx9pzhj 267 7 of of IN cord-005646-xhx9pzhj 267 8 variance variance NN cord-005646-xhx9pzhj 267 9 with with IN cord-005646-xhx9pzhj 267 10 repeated repeat VBN cord-005646-xhx9pzhj 267 11 measures measure NNS cord-005646-xhx9pzhj 267 12 . . . cord-005646-xhx9pzhj 268 1 ~ ~ NFP cord-005646-xhx9pzhj 268 2 < < XX cord-005646-xhx9pzhj 268 3 0.05 0.05 CD cord-005646-xhx9pzhj 268 4 vs. vs. IN cord-005646-xhx9pzhj 268 5 VCV VCV NNP cord-005646-xhx9pzhj 268 6 ) ) -RRB- cord-005646-xhx9pzhj 269 1 VCV VCV NNP cord-005646-xhx9pzhj 269 2 PCV PCV NNP cord-005646-xhx9pzhj 269 3 ~ ~ NFP cord-005646-xhx9pzhj 270 1 Initial initial JJ cord-005646-xhx9pzhj 270 2 ] ] -RRB- cord-005646-xhx9pzhj 270 3 Final final JJ cord-005646-xhx9pzhj 270 4 ! ! . cord-005646-xhx9pzhj 271 1 CdlJn CdlJn NNP cord-005646-xhx9pzhj 272 1 3.5_+0.7 3.5_+0.7 CD cord-005646-xhx9pzhj 272 2 4.3_+0.8 4.3_+0.8 CD cord-005646-xhx9pzhj 272 3 * * NFP cord-005646-xhx9pzhj 272 4 3.7_+0.6 3.7_+0.6 CD cord-005646-xhx9pzhj 272 5 3.9_+0.7 3.9_+0.7 CD cord-005646-xhx9pzhj 272 6 I i NN cord-005646-xhx9pzhj 272 7 , , , cord-005646-xhx9pzhj 272 8 PIP PIP NNP cord-005646-xhx9pzhj 272 9 32 32 CD cord-005646-xhx9pzhj 272 10 + + SYM cord-005646-xhx9pzhj 272 11 1.0 1.0 CD cord-005646-xhx9pzhj 272 12 30L-_t.0 30L-_t.0 NNS cord-005646-xhx9pzhj 273 1 * * NFP cord-005646-xhx9pzhj 273 2 31_+1,0 31_+1,0 CD cord-005646-xhx9pzhj 273 3 31 31 CD cord-005646-xhx9pzhj 273 4 + + CC cord-005646-xhx9pzhj 273 5 -1,0 -1,0 NN cord-005646-xhx9pzhj 274 1 Paw paw NN cord-005646-xhx9pzhj 274 2 9.2_+0.6 9.2_+0.6 CD cord-005646-xhx9pzhj 275 1 10.9i-_0.7 10.9i-_0.7 CD cord-005646-xhx9pzhj 276 1 * * NFP cord-005646-xhx9pzhj 276 2 9.7 9.7 CD cord-005646-xhx9pzhj 276 3 + + CC cord-005646-xhx9pzhj 277 1 0.7 0.7 CD cord-005646-xhx9pzhj 278 1 10.0-!-_0.8 10.0-!-_0.8 CD cord-005646-xhx9pzhj 278 2 PaO2 PaO2 NNS cord-005646-xhx9pzhj 279 1 97_+14 97_+14 CD cord-005646-xhx9pzhj 279 2 92 92 CD cord-005646-xhx9pzhj 279 3 + + CD cord-005646-xhx9pzhj 280 1 -10 -10 IN cord-005646-xhx9pzhj 280 2 87_+9 87_+9 CD cord-005646-xhx9pzhj 280 3 97_+14 97_+14 CD cord-005646-xhx9pzhj 280 4 Discussion discussion NN cord-005646-xhx9pzhj 280 5 : : : cord-005646-xhx9pzhj 281 1 At at IN cord-005646-xhx9pzhj 281 2 the the DT cord-005646-xhx9pzhj 281 3 same same JJ cord-005646-xhx9pzhj 281 4 minute minute NN cord-005646-xhx9pzhj 281 5 ventilation ventilation NN cord-005646-xhx9pzhj 281 6 , , , cord-005646-xhx9pzhj 281 7 the the DT cord-005646-xhx9pzhj 281 8 decelerating decelerate VBG cord-005646-xhx9pzhj 281 9 flow flow NN cord-005646-xhx9pzhj 281 10 pattern pattern NN cord-005646-xhx9pzhj 281 11 of of IN cord-005646-xhx9pzhj 281 12 PCV PCV NNP cord-005646-xhx9pzhj 281 13 resulted result VBD cord-005646-xhx9pzhj 281 14 in in IN cord-005646-xhx9pzhj 281 15 a a DT cord-005646-xhx9pzhj 281 16 23 23 CD cord-005646-xhx9pzhj 281 17 % % NN cord-005646-xhx9pzhj 281 18 increase increase NN cord-005646-xhx9pzhj 281 19 in in IN cord-005646-xhx9pzhj 281 20 Cdyn Cdyn NNP cord-005646-xhx9pzhj 281 21 and and CC cord-005646-xhx9pzhj 281 22 an an DT cord-005646-xhx9pzhj 281 23 18 18 CD cord-005646-xhx9pzhj 281 24 % % NN cord-005646-xhx9pzhj 281 25 increase increase NN cord-005646-xhx9pzhj 281 26 in in IN cord-005646-xhx9pzhj 281 27 Paw Paw NNP cord-005646-xhx9pzhj 281 28 while while IN cord-005646-xhx9pzhj 281 29 decreasing decrease VBG cord-005646-xhx9pzhj 281 30 PIP PIP NNP cord-005646-xhx9pzhj 281 31 by by IN cord-005646-xhx9pzhj 281 32 6 6 CD cord-005646-xhx9pzhj 281 33 % % NN cord-005646-xhx9pzhj 281 34 . . . cord-005646-xhx9pzhj 282 1 The the DT cord-005646-xhx9pzhj 282 2 lack lack NN cord-005646-xhx9pzhj 282 3 of of IN cord-005646-xhx9pzhj 282 4 a a DT cord-005646-xhx9pzhj 282 5 significant significant JJ cord-005646-xhx9pzhj 282 6 change change NN cord-005646-xhx9pzhj 282 7 in in IN cord-005646-xhx9pzhj 282 8 oxygenation oxygenation NN cord-005646-xhx9pzhj 282 9 may may MD cord-005646-xhx9pzhj 282 10 be be VB cord-005646-xhx9pzhj 282 11 a a DT cord-005646-xhx9pzhj 282 12 result result NN cord-005646-xhx9pzhj 282 13 of of IN cord-005646-xhx9pzhj 282 14 the the DT cord-005646-xhx9pzhj 282 15 limited limited JJ cord-005646-xhx9pzhj 282 16 time time NN cord-005646-xhx9pzhj 282 17 in in IN cord-005646-xhx9pzhj 282 18 each each DT cord-005646-xhx9pzhj 282 19 ventilator ventilator NN cord-005646-xhx9pzhj 282 20 mode mode NN cord-005646-xhx9pzhj 282 21 as as RB cord-005646-xhx9pzhj 282 22 well well RB cord-005646-xhx9pzhj 282 23 as as IN cord-005646-xhx9pzhj 282 24 the the DT cord-005646-xhx9pzhj 282 25 inclusion inclusion NN cord-005646-xhx9pzhj 282 26 of of IN cord-005646-xhx9pzhj 282 27 patients patient NNS cord-005646-xhx9pzhj 282 28 with with IN cord-005646-xhx9pzhj 282 29 both both CC cord-005646-xhx9pzhj 282 30 normal normal JJ cord-005646-xhx9pzhj 282 31 and and CC cord-005646-xhx9pzhj 282 32 abnormal abnormal JJ cord-005646-xhx9pzhj 282 33 lungs lung NNS cord-005646-xhx9pzhj 282 34 . . . cord-005646-xhx9pzhj 283 1 There there EX cord-005646-xhx9pzhj 283 2 was be VBD cord-005646-xhx9pzhj 283 3 no no DT cord-005646-xhx9pzhj 283 4 significant significant JJ cord-005646-xhx9pzhj 283 5 difference difference NN cord-005646-xhx9pzhj 283 6 in in IN cord-005646-xhx9pzhj 283 7 initial initial JJ cord-005646-xhx9pzhj 283 8 and and CC cord-005646-xhx9pzhj 283 9 final final JJ cord-005646-xhx9pzhj 283 10 measurements measurement NNS cord-005646-xhx9pzhj 283 11 indicating indicate VBG cord-005646-xhx9pzhj 283 12 patient patient JJ cord-005646-xhx9pzhj 283 13 stability stability NN cord-005646-xhx9pzhj 283 14 . . . cord-005646-xhx9pzhj 284 1 The the DT cord-005646-xhx9pzhj 284 2 beneficial beneficial JJ cord-005646-xhx9pzhj 284 3 effects effect NNS cord-005646-xhx9pzhj 284 4 of of IN cord-005646-xhx9pzhj 284 5 iecre iecre NNS cord-005646-xhx9pzhj 284 6 ~ ~ NFP cord-005646-xhx9pzhj 284 7 L L NNP cord-005646-xhx9pzhj 284 8 ~ ~ NFP cord-005646-xhx9pzhj 284 9 iug iug NNP cord-005646-xhx9pzhj 284 10 Cdyn Cdyn NNP cord-005646-xhx9pzhj 284 11 and and CC cord-005646-xhx9pzhj 284 12 Paw Paw NNP cord-005646-xhx9pzhj 284 13 while while IN cord-005646-xhx9pzhj 284 14 decreasing decrease VBG cord-005646-xhx9pzhj 284 15 PIP PIP NNP cord-005646-xhx9pzhj 284 16 indicate indicate VBP cord-005646-xhx9pzhj 284 17 that that IN cord-005646-xhx9pzhj 284 18 PCV PCV NNP cord-005646-xhx9pzhj 284 19 may may MD cord-005646-xhx9pzhj 284 20 be be VB cord-005646-xhx9pzhj 284 21 a a DT cord-005646-xhx9pzhj 284 22 preferable preferable JJ cord-005646-xhx9pzhj 284 23 mode mode NN cord-005646-xhx9pzhj 284 24 of of IN cord-005646-xhx9pzhj 284 25 ventilation ventilation NN cord-005646-xhx9pzhj 284 26 in in IN cord-005646-xhx9pzhj 284 27 patients patient NNS cord-005646-xhx9pzhj 284 28 with with IN cord-005646-xhx9pzhj 284 29 lung lung NN cord-005646-xhx9pzhj 284 30 injury injury NN cord-005646-xhx9pzhj 284 31 . . . cord-005646-xhx9pzhj 285 1 Further further JJ cord-005646-xhx9pzhj 285 2 randomized randomized JJ cord-005646-xhx9pzhj 285 3 studies study NNS cord-005646-xhx9pzhj 285 4 examining examine VBG cord-005646-xhx9pzhj 285 5 the the DT cord-005646-xhx9pzhj 285 6 effect effect NN cord-005646-xhx9pzhj 285 7 of of IN cord-005646-xhx9pzhj 285 8 PCV pcv NN cord-005646-xhx9pzhj 285 9 on on IN cord-005646-xhx9pzhj 285 10 respiratory respiratory JJ cord-005646-xhx9pzhj 285 11 outcome outcome NN cord-005646-xhx9pzhj 285 12 measures measure NNS cord-005646-xhx9pzhj 285 13 in in IN cord-005646-xhx9pzhj 285 14 pediatrics pediatric NNS cord-005646-xhx9pzhj 285 15 are be VBP cord-005646-xhx9pzhj 285 16 indicated indicate VBN cord-005646-xhx9pzhj 285 17 . . . cord-005646-xhx9pzhj 286 1 Prolonged prolonged JJ cord-005646-xhx9pzhj 286 2 positive positive JJ cord-005646-xhx9pzhj 286 3 pressure pressure NN cord-005646-xhx9pzhj 286 4 ventilation ventilation NN cord-005646-xhx9pzhj 286 5 following follow VBG cord-005646-xhx9pzhj 286 6 repair repair NN cord-005646-xhx9pzhj 286 7 of of IN cord-005646-xhx9pzhj 286 8 CDH CDH NNP cord-005646-xhx9pzhj 286 9 is be VBZ cord-005646-xhx9pzhj 286 10 associated associate VBN cord-005646-xhx9pzhj 286 11 with with IN cord-005646-xhx9pzhj 286 12 a a DT cord-005646-xhx9pzhj 286 13 high high JJ cord-005646-xhx9pzhj 286 14 prevalence prevalence NN cord-005646-xhx9pzhj 286 15 of of IN cord-005646-xhx9pzhj 286 16 iatrogenic iatrogenic JJ cord-005646-xhx9pzhj 286 17 lung lung NN cord-005646-xhx9pzhj 286 18 injury injury NN cord-005646-xhx9pzhj 286 19 , , , cord-005646-xhx9pzhj 286 20 in in IN cord-005646-xhx9pzhj 286 21 our -PRON- PRP$ cord-005646-xhx9pzhj 286 22 unit unit NN cord-005646-xhx9pzhj 286 23 dudng dudng NNP cord-005646-xhx9pzhj 286 24 1981 1981 CD cord-005646-xhx9pzhj 286 25 - - SYM cord-005646-xhx9pzhj 286 26 1990 1990 CD cord-005646-xhx9pzhj 286 27 314 314 CD cord-005646-xhx9pzhj 286 28 late late JJ cord-005646-xhx9pzhj 286 29 deaths death NNS cord-005646-xhx9pzhj 286 30 after after IN cord-005646-xhx9pzhj 286 31 repair repair NN cord-005646-xhx9pzhj 286 32 of of IN cord-005646-xhx9pzhj 286 33 CDH CDH NNP cord-005646-xhx9pzhj 286 34 were be VBD cord-005646-xhx9pzhj 286 35 due due JJ cord-005646-xhx9pzhj 286 36 to to IN cord-005646-xhx9pzhj 286 37 chronic chronic JJ cord-005646-xhx9pzhj 286 38 lung lung NN cord-005646-xhx9pzhj 286 39 disease disease NN cord-005646-xhx9pzhj 286 40 . . . cord-005646-xhx9pzhj 287 1 Since since IN cord-005646-xhx9pzhj 287 2 1990 1990 CD cord-005646-xhx9pzhj 287 3 babies baby NNS cord-005646-xhx9pzhj 287 4 requiring require VBG cord-005646-xhx9pzhj 287 5 assisted assist VBN cord-005646-xhx9pzhj 287 6 ventilation ventilation NN cord-005646-xhx9pzhj 287 7 for for IN cord-005646-xhx9pzhj 287 8 more more JJR cord-005646-xhx9pzhj 287 9 than than IN cord-005646-xhx9pzhj 287 10 7days 7days CD cord-005646-xhx9pzhj 287 11 following follow VBG cord-005646-xhx9pzhj 287 12 surgery surgery NN cord-005646-xhx9pzhj 287 13 were be VBD cord-005646-xhx9pzhj 287 14 transferred transfer VBN cord-005646-xhx9pzhj 287 15 to to IN cord-005646-xhx9pzhj 287 16 a a DT cord-005646-xhx9pzhj 287 17 CNEP CNEP NNP cord-005646-xhx9pzhj 287 18 chamber chamber NN cord-005646-xhx9pzhj 287 19 to to TO cord-005646-xhx9pzhj 287 20 limit limit VB cord-005646-xhx9pzhj 287 21 lung lung NN cord-005646-xhx9pzhj 287 22 injury injury NN cord-005646-xhx9pzhj 287 23 . . . cord-005646-xhx9pzhj 288 1 CNEP CNEP NNP cord-005646-xhx9pzhj 288 2 of of IN cord-005646-xhx9pzhj 288 3 -6 -6 NNP cord-005646-xhx9pzhj 288 4 cm cm NNS cord-005646-xhx9pzhj 288 5 of of IN cord-005646-xhx9pzhj 288 6 H20 H20 NNP cord-005646-xhx9pzhj 288 7 was be VBD cord-005646-xhx9pzhj 288 8 combined combine VBN cord-005646-xhx9pzhj 288 9 with with IN cord-005646-xhx9pzhj 288 10 positive positive JJ cord-005646-xhx9pzhj 288 11 pressure pressure NN cord-005646-xhx9pzhj 288 12 ventilation ventilation NN cord-005646-xhx9pzhj 288 13 via via IN cord-005646-xhx9pzhj 288 14 an an DT cord-005646-xhx9pzhj 288 15 endotracheal endotracheal NN cord-005646-xhx9pzhj 288 16 tube tube NN cord-005646-xhx9pzhj 288 17 dudng dudng NN cord-005646-xhx9pzhj 288 18 the the DT cord-005646-xhx9pzhj 288 19 transition transition NN cord-005646-xhx9pzhj 288 20 phase phase NN cord-005646-xhx9pzhj 288 21 . . . cord-005646-xhx9pzhj 289 1 Immediate immediate JJ cord-005646-xhx9pzhj 289 2 reduction reduction NN cord-005646-xhx9pzhj 289 3 of of IN cord-005646-xhx9pzhj 289 4 peak peak NN cord-005646-xhx9pzhj 289 5 inspiratory inspiratory JJ cord-005646-xhx9pzhj 289 6 and and CC cord-005646-xhx9pzhj 289 7 positive positive JJ cord-005646-xhx9pzhj 289 8 end end NN cord-005646-xhx9pzhj 289 9 pressures pressure NNS cord-005646-xhx9pzhj 289 10 were be VBD cord-005646-xhx9pzhj 289 11 possible possible JJ cord-005646-xhx9pzhj 289 12 and and CC cord-005646-xhx9pzhj 289 13 following follow VBG cord-005646-xhx9pzhj 289 14 extubation extubation NN cord-005646-xhx9pzhj 289 15 respiratory respiratory JJ cord-005646-xhx9pzhj 289 16 support support NN cord-005646-xhx9pzhj 289 17 was be VBD cord-005646-xhx9pzhj 289 18 maintained maintain VBN cord-005646-xhx9pzhj 289 19 by by IN cord-005646-xhx9pzhj 289 20 CNEP CNEP NNP cord-005646-xhx9pzhj 289 21 v v NN cord-005646-xhx9pzhj 289 22 ~ ~ NFP cord-005646-xhx9pzhj 289 23 th th XX cord-005646-xhx9pzhj 289 24 appropriate appropriate JJ cord-005646-xhx9pzhj 289 25 inspired inspire VBN cord-005646-xhx9pzhj 289 26 oxygen oxygen NN cord-005646-xhx9pzhj 289 27 . . . cord-005646-xhx9pzhj 290 1 Overall overall JJ cord-005646-xhx9pzhj 290 2 outcome outcome NN cord-005646-xhx9pzhj 290 3 : : : cord-005646-xhx9pzhj 290 4 [ [ -LRB- cord-005646-xhx9pzhj 290 5 1981 1981 CD cord-005646-xhx9pzhj 290 6 ] ] -RRB- cord-005646-xhx9pzhj 290 7 [ [ -LRB- cord-005646-xhx9pzhj 290 8 1982 1982 CD cord-005646-xhx9pzhj 290 9 ] ] -RRB- cord-005646-xhx9pzhj 290 10 [ [ -LRB- cord-005646-xhx9pzhj 290 11 1983 1983 CD cord-005646-xhx9pzhj 290 12 ] ] -RRB- cord-005646-xhx9pzhj 291 1 [ [ -LRB- cord-005646-xhx9pzhj 291 2 1984 1984 CD cord-005646-xhx9pzhj 291 3 ] ] -RRB- cord-005646-xhx9pzhj 291 4 [ [ -LRB- cord-005646-xhx9pzhj 291 5 1985 1985 CD cord-005646-xhx9pzhj 291 6 ] ] -RRB- cord-005646-xhx9pzhj 291 7 [ [ -LRB- cord-005646-xhx9pzhj 291 8 1986 1986 CD cord-005646-xhx9pzhj 291 9 ] ] -RRB- cord-005646-xhx9pzhj 292 1 [ [ -LRB- cord-005646-xhx9pzhj 292 2 1987 1987 CD cord-005646-xhx9pzhj 292 3 ] ] -RRB- cord-005646-xhx9pzhj 292 4 [ [ -LRB- cord-005646-xhx9pzhj 292 5 1988 1988 CD cord-005646-xhx9pzhj 292 6 ] ] -RRB- cord-005646-xhx9pzhj 292 7 [ [ -LRB- cord-005646-xhx9pzhj 292 8 1989 1989 CD cord-005646-xhx9pzhj 292 9 ] ] -RRB- cord-005646-xhx9pzhj 293 1 [ [ -LRB- cord-005646-xhx9pzhj 293 2 1990 1990 CD cord-005646-xhx9pzhj 293 3 ] ] -RRB- cord-005646-xhx9pzhj 293 4 n=68 n=68 JJ cord-005646-xhx9pzhj 293 5 Deaths death NNS cord-005646-xhx9pzhj 293 6 before before IN cord-005646-xhx9pzhj 293 7 surgery surgery NN cord-005646-xhx9pzhj 293 8 ( ( -LRB- cord-005646-xhx9pzhj 293 9 % % NN cord-005646-xhx9pzhj 293 10 ) ) -RRB- cord-005646-xhx9pzhj 293 11 11 11 CD cord-005646-xhx9pzhj 294 1 ( ( -LRB- cord-005646-xhx9pzhj 294 2 ECMO ECMO NNP cord-005646-xhx9pzhj 294 3 During during IN cord-005646-xhx9pzhj 294 4 1990 1990 CD cord-005646-xhx9pzhj 294 5 -1995 -1995 XX cord-005646-xhx9pzhj 294 6 /16 /16 XX cord-005646-xhx9pzhj 294 7 who who WP cord-005646-xhx9pzhj 294 8 were be VBD cord-005646-xhx9pzhj 294 9 ventilated ventilate VBN cord-005646-xhx9pzhj 294 10 for for IN cord-005646-xhx9pzhj 294 11 more more JJR cord-005646-xhx9pzhj 294 12 than than IN cord-005646-xhx9pzhj 294 13 7 7 CD cord-005646-xhx9pzhj 294 14 days day NNS cord-005646-xhx9pzhj 294 15 received receive VBD cord-005646-xhx9pzhj 294 16 CNEP CNEP NNP cord-005646-xhx9pzhj 294 17 and and CC cord-005646-xhx9pzhj 294 18 there there EX cord-005646-xhx9pzhj 294 19 were be VBD cord-005646-xhx9pzhj 294 20 no no DT cord-005646-xhx9pzhj 294 21 deaths death NNS cord-005646-xhx9pzhj 294 22 and and CC cord-005646-xhx9pzhj 294 23 no no DT cord-005646-xhx9pzhj 294 24 chronic chronic JJ cord-005646-xhx9pzhj 294 25 lung lung NN cord-005646-xhx9pzhj 294 26 disease disease NN cord-005646-xhx9pzhj 294 27 in in IN cord-005646-xhx9pzhj 294 28 that that DT cord-005646-xhx9pzhj 294 29 group group NN cord-005646-xhx9pzhj 294 30 . . . cord-005646-xhx9pzhj 295 1 CNEP CNEP NNP cord-005646-xhx9pzhj 295 2 assisted assist VBN cord-005646-xhx9pzhj 295 3 ventilation ventilation NN cord-005646-xhx9pzhj 295 4 may may MD cord-005646-xhx9pzhj 295 5 be be VB cord-005646-xhx9pzhj 295 6 an an DT cord-005646-xhx9pzhj 295 7 important important JJ cord-005646-xhx9pzhj 295 8 management management NN cord-005646-xhx9pzhj 295 9 option option NN cord-005646-xhx9pzhj 295 10 for for IN cord-005646-xhx9pzhj 295 11 babies baby NNS cord-005646-xhx9pzhj 295 12 who who WP cord-005646-xhx9pzhj 295 13 require require VBP cord-005646-xhx9pzhj 295 14 prolonged prolonged JJ cord-005646-xhx9pzhj 295 15 respiratory respiratory JJ cord-005646-xhx9pzhj 295 16 support support NN cord-005646-xhx9pzhj 295 17 to to TO cord-005646-xhx9pzhj 295 18 avoid avoid VB cord-005646-xhx9pzhj 295 19 the the DT cord-005646-xhx9pzhj 295 20 adverse adverse JJ cord-005646-xhx9pzhj 295 21 effects effect NNS cord-005646-xhx9pzhj 295 22 of of IN cord-005646-xhx9pzhj 295 23 chronic chronic JJ cord-005646-xhx9pzhj 295 24 positive positive JJ cord-005646-xhx9pzhj 295 25 pressure pressure NN cord-005646-xhx9pzhj 295 26 ventilation ventilation NN cord-005646-xhx9pzhj 295 27 , , , cord-005646-xhx9pzhj 295 28 Introduction introduction NN cord-005646-xhx9pzhj 295 29 So so RB cord-005646-xhx9pzhj 295 30 far far RB cord-005646-xhx9pzhj 295 31 2 2 CD cord-005646-xhx9pzhj 295 32 modes mode NNS cord-005646-xhx9pzhj 295 33 of of IN cord-005646-xhx9pzhj 295 34 liquid liquid JJ cord-005646-xhx9pzhj 295 35 ventilation ventilation NN cord-005646-xhx9pzhj 295 36 ( ( -LRB- cord-005646-xhx9pzhj 295 37 LV LV NNP cord-005646-xhx9pzhj 295 38 ) ) -RRB- cord-005646-xhx9pzhj 295 39 have have VBP cord-005646-xhx9pzhj 295 40 been be VBN cord-005646-xhx9pzhj 295 41 used use VBN cord-005646-xhx9pzhj 295 42 in in IN cord-005646-xhx9pzhj 295 43 experimental experimental JJ cord-005646-xhx9pzhj 295 44 animals animal NNS cord-005646-xhx9pzhj 295 45 and and CC cord-005646-xhx9pzhj 295 46 , , , cord-005646-xhx9pzhj 295 47 exceptionally exceptionally RB cord-005646-xhx9pzhj 295 48 , , , cord-005646-xhx9pzhj 295 49 in in IN cord-005646-xhx9pzhj 295 50 humans human NNS cord-005646-xhx9pzhj 295 51 : : : cord-005646-xhx9pzhj 296 1 1 1 LS cord-005646-xhx9pzhj 296 2 . . . cord-005646-xhx9pzhj 297 1 total total JJ cord-005646-xhx9pzhj 297 2 liquid liquid JJ cord-005646-xhx9pzhj 297 3 ventilation ventilation NN cord-005646-xhx9pzhj 297 4 ( ( -LRB- cord-005646-xhx9pzhj 298 1 TLV)-functional tlv)-functional JJ cord-005646-xhx9pzhj 298 2 residual residual JJ cord-005646-xhx9pzhj 298 3 capacity capacity NN cord-005646-xhx9pzhj 298 4 ( ( -LRB- cord-005646-xhx9pzhj 298 5 FRC FRC NNP cord-005646-xhx9pzhj 298 6 ) ) -RRB- cord-005646-xhx9pzhj 298 7 is be VBZ cord-005646-xhx9pzhj 298 8 filled fill VBN cord-005646-xhx9pzhj 298 9 by by IN cord-005646-xhx9pzhj 298 10 perfluorocarbons perfluorocarbon NNS cord-005646-xhx9pzhj 298 11 ( ( -LRB- cord-005646-xhx9pzhj 298 12 PFC PFC NNP cord-005646-xhx9pzhj 298 13 ) ) -RRB- cord-005646-xhx9pzhj 298 14 , , , cord-005646-xhx9pzhj 298 15 and and CC cord-005646-xhx9pzhj 298 16 slow slow VB cord-005646-xhx9pzhj 298 17 tidal tidal JJ cord-005646-xhx9pzhj 298 18 volume volume NN cord-005646-xhx9pzhj 298 19 ( ( -LRB- cord-005646-xhx9pzhj 298 20 Tv tv NN cord-005646-xhx9pzhj 298 21 ) ) -RRB- cord-005646-xhx9pzhj 298 22 breathing breathing NN cord-005646-xhx9pzhj 298 23 is be VBZ cord-005646-xhx9pzhj 298 24 performed perform VBN cord-005646-xhx9pzhj 298 25 by by IN cord-005646-xhx9pzhj 298 26 PFC PFC NNP cord-005646-xhx9pzhj 298 27 . . . cord-005646-xhx9pzhj 299 1 2 2 LS cord-005646-xhx9pzhj 299 2 . . . cord-005646-xhx9pzhj 300 1 partial partial JJ cord-005646-xhx9pzhj 300 2 liquid liquid NN cord-005646-xhx9pzhj 300 3 ve,0ti ve,0ti NNP cord-005646-xhx9pzhj 300 4 , , , cord-005646-xhx9pzhj 300 5 la la NN cord-005646-xhx9pzhj 300 6 ~ ~ NFP cord-005646-xhx9pzhj 300 7 ion ion NN cord-005646-xhx9pzhj 300 8 ( ( -LRB- cord-005646-xhx9pzhj 300 9 PAGE page NN cord-005646-xhx9pzhj 300 10 ) ) -RRB- cord-005646-xhx9pzhj 300 11 -only -only . cord-005646-xhx9pzhj 301 1 FRC FRC NNP cord-005646-xhx9pzhj 301 2 is be VBZ cord-005646-xhx9pzhj 301 3 filled fill VBN cord-005646-xhx9pzhj 301 4 by by IN cord-005646-xhx9pzhj 301 5 PFC PFC NNP cord-005646-xhx9pzhj 301 6 . . . cord-005646-xhx9pzhj 302 1 Gas gas NN cord-005646-xhx9pzhj 302 2 Tv Tv NNP cord-005646-xhx9pzhj 302 3 is be VBZ cord-005646-xhx9pzhj 302 4 delivered deliver VBN cord-005646-xhx9pzhj 302 5 by by IN cord-005646-xhx9pzhj 302 6 conventional conventional JJ cord-005646-xhx9pzhj 302 7 mechanical mechanical JJ cord-005646-xhx9pzhj 302 8 ventilation ventilation NN cord-005646-xhx9pzhj 302 9 ( ( -LRB- cord-005646-xhx9pzhj 302 10 CMV CMV NNP cord-005646-xhx9pzhj 302 11 ) ) -RRB- cord-005646-xhx9pzhj 302 12 , , , cord-005646-xhx9pzhj 302 13 high high JJ cord-005646-xhx9pzhj 302 14 frequency frequency NN cord-005646-xhx9pzhj 302 15 jet jet NN cord-005646-xhx9pzhj 302 16 ventilation ventilation NN cord-005646-xhx9pzhj 302 17 ( ( -LRB- cord-005646-xhx9pzhj 302 18 HFJV HFJV NNP cord-005646-xhx9pzhj 302 19 ) ) -RRB- cord-005646-xhx9pzhj 302 20 or or CC cord-005646-xhx9pzhj 302 21 high high JJ cord-005646-xhx9pzhj 302 22 frequency frequency NN cord-005646-xhx9pzhj 302 23 oscillation oscillation NN cord-005646-xhx9pzhj 302 24 ( ( -LRB- cord-005646-xhx9pzhj 302 25 HFO HFO NNP cord-005646-xhx9pzhj 302 26 ) ) -RRB- cord-005646-xhx9pzhj 302 27 . . . cord-005646-xhx9pzhj 303 1 The the DT cord-005646-xhx9pzhj 303 2 aim aim NN cord-005646-xhx9pzhj 303 3 of of IN cord-005646-xhx9pzhj 303 4 our -PRON- PRP$ cord-005646-xhx9pzhj 303 5 study study NN cord-005646-xhx9pzhj 303 6 is be VBZ cord-005646-xhx9pzhj 303 7 to to TO cord-005646-xhx9pzhj 303 8 present present VB cord-005646-xhx9pzhj 303 9 our -PRON- PRP$ cord-005646-xhx9pzhj 303 10 limited limited JJ cord-005646-xhx9pzhj 303 11 experience experience NN cord-005646-xhx9pzhj 303 12 with with IN cord-005646-xhx9pzhj 303 13 PAGE page NN cord-005646-xhx9pzhj 303 14 in in IN cord-005646-xhx9pzhj 303 15 newborns newborn NNS cord-005646-xhx9pzhj 303 16 and and CC cord-005646-xhx9pzhj 303 17 infants infant NNS cord-005646-xhx9pzhj 303 18 . . . cord-005646-xhx9pzhj 304 1 PAGE page NN cord-005646-xhx9pzhj 304 2 was be VBD cord-005646-xhx9pzhj 304 3 used use VBN cord-005646-xhx9pzhj 304 4 in in IN cord-005646-xhx9pzhj 304 5 two two CD cord-005646-xhx9pzhj 304 6 groups group NNS cord-005646-xhx9pzhj 304 7 of of IN cord-005646-xhx9pzhj 304 8 infants infant NNS cord-005646-xhx9pzhj 304 9 : : : cord-005646-xhx9pzhj 304 10 1 1 CD cord-005646-xhx9pzhj 304 11 , , , cord-005646-xhx9pzhj 304 12 in in IN cord-005646-xhx9pzhj 304 13 2 2 CD cord-005646-xhx9pzhj 304 14 infants infant NNS cord-005646-xhx9pzhj 304 15 with with IN cord-005646-xhx9pzhj 304 16 brain brain NN cord-005646-xhx9pzhj 304 17 death death NN cord-005646-xhx9pzhj 304 18 before before IN cord-005646-xhx9pzhj 304 19 disconnection disconnection NN cord-005646-xhx9pzhj 304 20 from from IN cord-005646-xhx9pzhj 304 21 CMV CMV NNP cord-005646-xhx9pzhj 304 22 , , , cord-005646-xhx9pzhj 304 23 because because IN cord-005646-xhx9pzhj 304 24 recipients recipient NNS cord-005646-xhx9pzhj 304 25 for for IN cord-005646-xhx9pzhj 304 26 organ organ NN cord-005646-xhx9pzhj 304 27 transplantation transplantation NN cord-005646-xhx9pzhj 304 28 were be VBD cord-005646-xhx9pzhj 304 29 not not RB cord-005646-xhx9pzhj 304 30 available available JJ cord-005646-xhx9pzhj 304 31 . . . cord-005646-xhx9pzhj 305 1 These these DT cord-005646-xhx9pzhj 305 2 infants infant NNS cord-005646-xhx9pzhj 305 3 have have VBP cord-005646-xhx9pzhj 305 4 relatively relatively RB cord-005646-xhx9pzhj 305 5 normal normal JJ cord-005646-xhx9pzhj 305 6 lungs lung NNS cord-005646-xhx9pzhj 305 7 ( ( -LRB- cord-005646-xhx9pzhj 305 8 FiO~ fio~ VB cord-005646-xhx9pzhj 305 9 less less JJR cord-005646-xhx9pzhj 305 10 than than IN cord-005646-xhx9pzhj 305 11 0.4 0.4 CD cord-005646-xhx9pzhj 305 12 ) ) -RRB- cord-005646-xhx9pzhj 305 13 . . . cord-005646-xhx9pzhj 306 1 Infants infant NNS cord-005646-xhx9pzhj 306 2 stayed stay VBD cord-005646-xhx9pzhj 306 3 on on IN cord-005646-xhx9pzhj 306 4 PAGE page NN cord-005646-xhx9pzhj 306 5 for for IN cord-005646-xhx9pzhj 306 6 1 1 CD cord-005646-xhx9pzhj 306 7 hour hour NN cord-005646-xhx9pzhj 306 8 , , , cord-005646-xhx9pzhj 306 9 during during IN cord-005646-xhx9pzhj 306 10 that that DT cord-005646-xhx9pzhj 306 11 period period NN cord-005646-xhx9pzhj 306 12 no no DT cord-005646-xhx9pzhj 306 13 ventdator ventdator NN cord-005646-xhx9pzhj 306 14 manipulations manipulation NNS cord-005646-xhx9pzhj 306 15 were be VBD cord-005646-xhx9pzhj 306 16 made make VBN cord-005646-xhx9pzhj 306 17 . . . cord-005646-xhx9pzhj 307 1 After after IN cord-005646-xhx9pzhj 307 2 PAGE page NN cord-005646-xhx9pzhj 307 3 , , , cord-005646-xhx9pzhj 307 4 infant infant NN cord-005646-xhx9pzhj 307 5 were be VBD cord-005646-xhx9pzhj 307 6 switched switch VBN cord-005646-xhx9pzhj 307 7 to to IN cord-005646-xhx9pzhj 307 8 CMV CMV NNP cord-005646-xhx9pzhj 307 9 for for IN cord-005646-xhx9pzhj 307 10 next next JJ cord-005646-xhx9pzhj 307 11 6 6 CD cord-005646-xhx9pzhj 307 12 hours hour NNS cord-005646-xhx9pzhj 307 13 . . . cord-005646-xhx9pzhj 308 1 2 2 LS cord-005646-xhx9pzhj 308 2 . . . cord-005646-xhx9pzhj 308 3 very very RB cord-005646-xhx9pzhj 308 4 critically critically RB cord-005646-xhx9pzhj 308 5 diseased diseased JJ cord-005646-xhx9pzhj 308 6 infants infant NNS cord-005646-xhx9pzhj 308 7 with with IN cord-005646-xhx9pzhj 308 8 ARDS ARDS NNP cord-005646-xhx9pzhj 308 9 ( ( -LRB- cord-005646-xhx9pzhj 308 10 RDS RDS NNP cord-005646-xhx9pzhj 308 11 ) ) -RRB- cord-005646-xhx9pzhj 308 12 -2 -2 VBN cord-005646-xhx9pzhj 308 13 on on IN cord-005646-xhx9pzhj 308 14 ECMO ECMO NNP cord-005646-xhx9pzhj 308 15 more more JJR cord-005646-xhx9pzhj 308 16 than than IN cord-005646-xhx9pzhj 308 17 5 5 CD cord-005646-xhx9pzhj 308 18 days day NNS cord-005646-xhx9pzhj 308 19 , , , cord-005646-xhx9pzhj 308 20 1 1 CD cord-005646-xhx9pzhj 308 21 before before IN cord-005646-xhx9pzhj 308 22 cannulation cannulation NN cord-005646-xhx9pzhj 308 23 for for IN cord-005646-xhx9pzhj 308 24 ECMO ECMO NNP cord-005646-xhx9pzhj 308 25 , , , cord-005646-xhx9pzhj 308 26 4 4 CD cord-005646-xhx9pzhj 308 27 on on IN cord-005646-xhx9pzhj 308 28 HFO HFO NNP cord-005646-xhx9pzhj 308 29 because because IN cord-005646-xhx9pzhj 308 30 of of IN cord-005646-xhx9pzhj 308 31 intractable intractable JJ cord-005646-xhx9pzhj 308 32 respiratory respiratory JJ cord-005646-xhx9pzhj 308 33 failure failure NN cord-005646-xhx9pzhj 308 34 , , , cord-005646-xhx9pzhj 308 35 Preoxygenated Preoxygenated NNP cord-005646-xhx9pzhj 308 36 RM RM NNP cord-005646-xhx9pzhj 308 37 101 101 CD cord-005646-xhx9pzhj 308 38 ( ( -LRB- cord-005646-xhx9pzhj 308 39 Miteni Miteni NNP cord-005646-xhx9pzhj 308 40 , , , cord-005646-xhx9pzhj 308 41 Italy Italy NNP cord-005646-xhx9pzhj 308 42 ) ) -RRB- cord-005646-xhx9pzhj 308 43 was be VBD cord-005646-xhx9pzhj 308 44 used use VBN cord-005646-xhx9pzhj 308 45 in in IN cord-005646-xhx9pzhj 308 46 the the DT cord-005646-xhx9pzhj 308 47 doses dose NNS cord-005646-xhx9pzhj 308 48 up up IN cord-005646-xhx9pzhj 308 49 to to TO cord-005646-xhx9pzhj 308 50 40 40 CD cord-005646-xhx9pzhj 308 51 ml ml NNS cord-005646-xhx9pzhj 308 52 / / SYM cord-005646-xhx9pzhj 308 53 kg kg NNP cord-005646-xhx9pzhj 308 54 intratrachealy intratrachealy NNS cord-005646-xhx9pzhj 308 55 . . . cord-005646-xhx9pzhj 309 1 Blood blood NN cord-005646-xhx9pzhj 309 2 gases gas NNS cord-005646-xhx9pzhj 309 3 and and CC cord-005646-xhx9pzhj 309 4 parameters parameter NNS cord-005646-xhx9pzhj 309 5 of of IN cord-005646-xhx9pzhj 309 6 pulmonary pulmonary JJ cord-005646-xhx9pzhj 309 7 mechanics mechanic NNS cord-005646-xhx9pzhj 309 8 were be VBD cord-005646-xhx9pzhj 309 9 followed follow VBN cord-005646-xhx9pzhj 309 10 ( ( -LRB- cord-005646-xhx9pzhj 309 11 dynamic dynamic JJ cord-005646-xhx9pzhj 309 12 compliance compliance NN cord-005646-xhx9pzhj 309 13 -C -C : cord-005646-xhx9pzhj 309 14 dyn dyn NNP cord-005646-xhx9pzhj 309 15 , , , cord-005646-xhx9pzhj 309 16 airway airway NN cord-005646-xhx9pzhj 309 17 resistance resistance NN cord-005646-xhx9pzhj 309 18 -Raw -raw NN cord-005646-xhx9pzhj 309 19 , , , cord-005646-xhx9pzhj 309 20 Bicore Bicore NNP cord-005646-xhx9pzhj 309 21 monitor monitor NN cord-005646-xhx9pzhj 309 22 ) ) -RRB- cord-005646-xhx9pzhj 309 23 . . . cord-005646-xhx9pzhj 310 1 PAGE page NN cord-005646-xhx9pzhj 310 2 was be VBD cord-005646-xhx9pzhj 310 3 combined combine VBN cord-005646-xhx9pzhj 310 4 with with IN cord-005646-xhx9pzhj 310 5 NO no DT cord-005646-xhx9pzhj 310 6 inhalation inhalation NN cord-005646-xhx9pzhj 310 7 ( ( -LRB- cord-005646-xhx9pzhj 310 8 5 5 CD cord-005646-xhx9pzhj 310 9 - - SYM cord-005646-xhx9pzhj 310 10 80 80 CD cord-005646-xhx9pzhj 310 11 p.p.m p.p.m NN cord-005646-xhx9pzhj 310 12 , , , cord-005646-xhx9pzhj 310 13 in in IN cord-005646-xhx9pzhj 310 14 2 2 CD cord-005646-xhx9pzhj 310 15 infants infant NNS cord-005646-xhx9pzhj 310 16 ) ) -RRB- cord-005646-xhx9pzhj 310 17 . . . cord-005646-xhx9pzhj 311 1 In in IN cord-005646-xhx9pzhj 311 2 both both DT cord-005646-xhx9pzhj 311 3 groups group NNS cord-005646-xhx9pzhj 311 4 ad ad FW cord-005646-xhx9pzhj 311 5 hoc hoc FW cord-005646-xhx9pzhj 311 6 an an DT cord-005646-xhx9pzhj 311 7 approvement approvement NN cord-005646-xhx9pzhj 311 8 from from IN cord-005646-xhx9pzhj 311 9 e e DT cord-005646-xhx9pzhj 311 10 local local JJ cord-005646-xhx9pzhj 311 11 ethical ethical JJ cord-005646-xhx9pzhj 311 12 commission commission NN cord-005646-xhx9pzhj 311 13 and and CC cord-005646-xhx9pzhj 311 14 informed inform VBN cord-005646-xhx9pzhj 311 15 parental parental JJ cord-005646-xhx9pzhj 311 16 consent consent NN cord-005646-xhx9pzhj 311 17 were be VBD cord-005646-xhx9pzhj 311 18 obtained obtain VBN cord-005646-xhx9pzhj 311 19 . . . cord-005646-xhx9pzhj 312 1 In in IN cord-005646-xhx9pzhj 312 2 the the DT cord-005646-xhx9pzhj 312 3 first first JJ cord-005646-xhx9pzhj 312 4 QrouD QrouD NNP cord-005646-xhx9pzhj 312 5 with with IN cord-005646-xhx9pzhj 312 6 relatively relatively RB cord-005646-xhx9pzhj 312 7 normal normal JJ cord-005646-xhx9pzhj 312 8 lung lung NN cord-005646-xhx9pzhj 312 9 parameters parameter NNS cord-005646-xhx9pzhj 312 10 of of IN cord-005646-xhx9pzhj 312 11 oxygenation oxygenation NN cord-005646-xhx9pzhj 312 12 drops drop NNS cord-005646-xhx9pzhj 312 13 after after IN cord-005646-xhx9pzhj 312 14 PFC PFC NNP cord-005646-xhx9pzhj 312 15 instilation instilation NN cord-005646-xhx9pzhj 312 16 intratracheally intratracheally RB cord-005646-xhx9pzhj 312 17 and and CC cord-005646-xhx9pzhj 312 18 stayed stay VBD cord-005646-xhx9pzhj 312 19 depressed depressed JJ cord-005646-xhx9pzhj 312 20 for for IN cord-005646-xhx9pzhj 312 21 4 4 CD cord-005646-xhx9pzhj 312 22 - - SYM cord-005646-xhx9pzhj 312 23 6 6 CD cord-005646-xhx9pzhj 312 24 hours hour NNS cord-005646-xhx9pzhj 312 25 . . . cord-005646-xhx9pzhj 313 1 Slight Slight NNP cord-005646-xhx9pzhj 313 2 pCO2 pCO2 NNP cord-005646-xhx9pzhj 313 3 retention retention NN cord-005646-xhx9pzhj 313 4 occured occur VBN cord-005646-xhx9pzhj 313 5 in in IN cord-005646-xhx9pzhj 313 6 both both DT cord-005646-xhx9pzhj 313 7 cases case NNS cord-005646-xhx9pzhj 313 8 during during IN cord-005646-xhx9pzhj 313 9 PAGE page NN cord-005646-xhx9pzhj 313 10 . . . cord-005646-xhx9pzhj 314 1 C C NNP cord-005646-xhx9pzhj 314 2 dyn dyn NNP cord-005646-xhx9pzhj 314 3 increased increase VBD cord-005646-xhx9pzhj 314 4 almost almost RB cord-005646-xhx9pzhj 314 5 double double JJ cord-005646-xhx9pzhj 314 6 during during IN cord-005646-xhx9pzhj 314 7 PAGE page NN cord-005646-xhx9pzhj 314 8 period period NN cord-005646-xhx9pzhj 314 9 , , , cord-005646-xhx9pzhj 314 10 Raw Raw NNP cord-005646-xhx9pzhj 314 11 drops drop VBZ cord-005646-xhx9pzhj 314 12 transitorily transitorily NN cord-005646-xhx9pzhj 314 13 after after IN cord-005646-xhx9pzhj 314 14 PFC PFC NNP cord-005646-xhx9pzhj 314 15 instilation instilation NN cord-005646-xhx9pzhj 314 16 but but CC cord-005646-xhx9pzhj 314 17 in in IN cord-005646-xhx9pzhj 314 18 10 10 CD cord-005646-xhx9pzhj 314 19 minutes minute NNS cord-005646-xhx9pzhj 314 20 they -PRON- PRP cord-005646-xhx9pzhj 314 21 were be VBD cord-005646-xhx9pzhj 314 22 identical identical JJ cord-005646-xhx9pzhj 314 23 like like IN cord-005646-xhx9pzhj 314 24 in in IN cord-005646-xhx9pzhj 314 25 prePAGE prepage CD cord-005646-xhx9pzhj 314 26 period period NN cord-005646-xhx9pzhj 314 27 , , , cord-005646-xhx9pzhj 314 28 Parameters parameter NNS cord-005646-xhx9pzhj 314 29 of of IN cord-005646-xhx9pzhj 314 30 oxygenation oxygenation NN cord-005646-xhx9pzhj 314 31 ( ( -LRB- cord-005646-xhx9pzhj 314 32 PeO2 PeO2 NNS cord-005646-xhx9pzhj 314 33 / / SYM cord-005646-xhx9pzhj 314 34 FiO2 FiO2 NNS cord-005646-xhx9pzhj 314 35 ) ) -RRB- cord-005646-xhx9pzhj 314 36 after after IN cord-005646-xhx9pzhj 314 37 4 4 CD cord-005646-xhx9pzhj 314 38 - - SYM cord-005646-xhx9pzhj 314 39 6 6 CD cord-005646-xhx9pzhj 314 40 hours hour NNS cord-005646-xhx9pzhj 314 41 after after IN cord-005646-xhx9pzhj 314 42 PAGE page NN cord-005646-xhx9pzhj 314 43 improved improve VBD cord-005646-xhx9pzhj 314 44 and and CC cord-005646-xhx9pzhj 314 45 were be VBD cord-005646-xhx9pzhj 314 46 better well JJR cord-005646-xhx9pzhj 314 47 than than IN cord-005646-xhx9pzhj 314 48 in in IN cord-005646-xhx9pzhj 314 49 prePAGE prepage CD cord-005646-xhx9pzhj 314 50 period period NN cord-005646-xhx9pzhj 314 51 . . . cord-005646-xhx9pzhj 315 1 After after IN cord-005646-xhx9pzhj 315 2 that that DT cord-005646-xhx9pzhj 315 3 time time NN cord-005646-xhx9pzhj 315 4 infants infant NNS cord-005646-xhx9pzhj 315 5 were be VBD cord-005646-xhx9pzhj 315 6 disconnected disconnect VBN cord-005646-xhx9pzhj 315 7 and and CC cord-005646-xhx9pzhj 315 8 died die VBN cord-005646-xhx9pzhj 315 9 . . . cord-005646-xhx9pzhj 316 1 In in IN cord-005646-xhx9pzhj 316 2 the the DT cord-005646-xhx9pzhj 316 3 second second JJ cord-005646-xhx9pzhj 316 4 group group NN cord-005646-xhx9pzhj 316 5 no no DT cord-005646-xhx9pzhj 316 6 improvement improvement NN cord-005646-xhx9pzhj 316 7 of of IN cord-005646-xhx9pzhj 316 8 oxygenation oxygenation NN cord-005646-xhx9pzhj 316 9 was be VBD cord-005646-xhx9pzhj 316 10 seen see VBN cord-005646-xhx9pzhj 316 11 in in IN cord-005646-xhx9pzhj 316 12 one one CD cord-005646-xhx9pzhj 316 13 ECMO ECMO NNP cord-005646-xhx9pzhj 316 14 baby baby NN cord-005646-xhx9pzhj 316 15 , , , cord-005646-xhx9pzhj 316 16 in in IN cord-005646-xhx9pzhj 316 17 spite spite NN cord-005646-xhx9pzhj 316 18 ( ( -LRB- cord-005646-xhx9pzhj 316 19 ) ) -RRB- cord-005646-xhx9pzhj 316 20 f f LS cord-005646-xhx9pzhj 316 21 transient transient JJ cord-005646-xhx9pzhj 316 22 improvement improvement NN cord-005646-xhx9pzhj 316 23 of of IN cord-005646-xhx9pzhj 316 24 C C NNP cord-005646-xhx9pzhj 316 25 dyn dyn NNP cord-005646-xhx9pzhj 316 26 . . . cord-005646-xhx9pzhj 317 1 In in IN cord-005646-xhx9pzhj 317 2 the the DT cord-005646-xhx9pzhj 317 3 second second JJ cord-005646-xhx9pzhj 317 4 ECMO ECMO NNP cord-005646-xhx9pzhj 317 5 baby baby NN cord-005646-xhx9pzhj 317 6 , , , cord-005646-xhx9pzhj 317 7 oxygenation oxygenation NN cord-005646-xhx9pzhj 317 8 improved improve VBN cord-005646-xhx9pzhj 317 9 and and CC cord-005646-xhx9pzhj 317 10 flow flow NN cord-005646-xhx9pzhj 317 11 of of IN cord-005646-xhx9pzhj 317 12 pump pump NN cord-005646-xhx9pzhj 317 13 could could MD cord-005646-xhx9pzhj 317 14 be be VB cord-005646-xhx9pzhj 317 15 decreased decrease VBN cord-005646-xhx9pzhj 317 16 by by IN cord-005646-xhx9pzhj 317 17 more more JJR cord-005646-xhx9pzhj 317 18 than than IN cord-005646-xhx9pzhj 317 19 20 20 CD cord-005646-xhx9pzhj 317 20 % % NN cord-005646-xhx9pzhj 317 21 . . . cord-005646-xhx9pzhj 318 1 None none NN cord-005646-xhx9pzhj 318 2 of of IN cord-005646-xhx9pzhj 318 3 these these DT cord-005646-xhx9pzhj 318 4 babies baby NNS cord-005646-xhx9pzhj 318 5 , , , cord-005646-xhx9pzhj 318 6 however however RB cord-005646-xhx9pzhj 318 7 , , , cord-005646-xhx9pzhj 318 8 survived survive VBD cord-005646-xhx9pzhj 318 9 , , , cord-005646-xhx9pzhj 318 10 improvement improvement NN cord-005646-xhx9pzhj 318 11 was be VBD cord-005646-xhx9pzhj 318 12 only only RB cord-005646-xhx9pzhj 318 13 transient transient JJ cord-005646-xhx9pzhj 318 14 in in IN cord-005646-xhx9pzhj 318 15 spite spite NN cord-005646-xhx9pzhj 318 16 of of IN cord-005646-xhx9pzhj 318 17 repeated repeat VBN cord-005646-xhx9pzhj 318 18 dosis dosis NN cord-005646-xhx9pzhj 318 19 of of IN cord-005646-xhx9pzhj 318 20 PFC PFC NNP cord-005646-xhx9pzhj 318 21 . . . cord-005646-xhx9pzhj 319 1 In in IN cord-005646-xhx9pzhj 319 2 these these DT cord-005646-xhx9pzhj 319 3 babies baby NNS cord-005646-xhx9pzhj 319 4 serious serious JJ cord-005646-xhx9pzhj 319 5 problems problem NNS cord-005646-xhx9pzhj 319 6 were be VBD cord-005646-xhx9pzhj 319 7 to to TO cord-005646-xhx9pzhj 319 8 maintain maintain VB cord-005646-xhx9pzhj 319 9 the the DT cord-005646-xhx9pzhj 319 10 adequate adequate JJ cord-005646-xhx9pzhj 319 11 FRC FRC NNP cord-005646-xhx9pzhj 319 12 by by IN cord-005646-xhx9pzhj 319 13 liquid liquid NN cord-005646-xhx9pzhj 319 14 , , , cord-005646-xhx9pzhj 319 15 because because IN cord-005646-xhx9pzhj 319 16 of of IN cord-005646-xhx9pzhj 319 17 severe severe JJ cord-005646-xhx9pzhj 319 18 air air NN cord-005646-xhx9pzhj 319 19 leak leak NN cord-005646-xhx9pzhj 319 20 , , , cord-005646-xhx9pzhj 319 21 In in IN cord-005646-xhx9pzhj 319 22 5 5 CD cord-005646-xhx9pzhj 319 23 babies baby NNS cord-005646-xhx9pzhj 319 24 on on IN cord-005646-xhx9pzhj 319 25 HFO HFO NNP cord-005646-xhx9pzhj 319 26 / / SYM cord-005646-xhx9pzhj 319 27 HFJV HFJV NNP cord-005646-xhx9pzhj 319 28 with with IN cord-005646-xhx9pzhj 319 29 severe severe JJ cord-005646-xhx9pzhj 319 30 ARDS ARDS NNP cord-005646-xhx9pzhj 319 31 / / SYM cord-005646-xhx9pzhj 319 32 RDS RDS NNP cord-005646-xhx9pzhj 320 1 the the DT cord-005646-xhx9pzhj 320 2 improvement improvement NN cord-005646-xhx9pzhj 320 3 of of IN cord-005646-xhx9pzhj 320 4 oxygenation oxygenation NN cord-005646-xhx9pzhj 320 5 were be VBD cord-005646-xhx9pzhj 320 6 seen see VBN cord-005646-xhx9pzhj 320 7 in in IN cord-005646-xhx9pzhj 320 8 all all PDT cord-005646-xhx9pzhj 320 9 the the DT cord-005646-xhx9pzhj 320 10 cases case NNS cord-005646-xhx9pzhj 320 11 immediately immediately RB cord-005646-xhx9pzhj 320 12 after after IN cord-005646-xhx9pzhj 320 13 PFC PFC NNP cord-005646-xhx9pzhj 320 14 instiletion instiletion NN cord-005646-xhx9pzhj 320 15 for for IN cord-005646-xhx9pzhj 320 16 the the DT cord-005646-xhx9pzhj 320 17 period period NN cord-005646-xhx9pzhj 320 18 of of IN cord-005646-xhx9pzhj 320 19 4 4 CD cord-005646-xhx9pzhj 320 20 - - SYM cord-005646-xhx9pzhj 320 21 5 5 CD cord-005646-xhx9pzhj 320 22 hours hour NNS cord-005646-xhx9pzhj 320 23 . . . cord-005646-xhx9pzhj 321 1 After after IN cord-005646-xhx9pzhj 321 2 that that DT cord-005646-xhx9pzhj 321 3 period period NN cord-005646-xhx9pzhj 321 4 , , , cord-005646-xhx9pzhj 321 5 PFC PFC NNP cord-005646-xhx9pzhj 321 6 dose dose NN cord-005646-xhx9pzhj 321 7 had have VBD cord-005646-xhx9pzhj 321 8 to to TO cord-005646-xhx9pzhj 321 9 be be VB cord-005646-xhx9pzhj 321 10 repeated repeat VBN cord-005646-xhx9pzhj 321 11 . . . cord-005646-xhx9pzhj 322 1 Two two CD cord-005646-xhx9pzhj 322 2 babies baby NNS cord-005646-xhx9pzhj 322 3 of of IN cord-005646-xhx9pzhj 322 4 this this DT cord-005646-xhx9pzhj 322 5 group group NN cord-005646-xhx9pzhj 322 6 survived survive VBD cord-005646-xhx9pzhj 322 7 . . . cord-005646-xhx9pzhj 323 1 Conclusion conclusion NN cord-005646-xhx9pzhj 323 2 . . . cord-005646-xhx9pzhj 324 1 PAGE page NN cord-005646-xhx9pzhj 324 2 is be VBZ cord-005646-xhx9pzhj 324 3 going go VBG cord-005646-xhx9pzhj 324 4 steadily steadily RB cord-005646-xhx9pzhj 324 5 from from IN cord-005646-xhx9pzhj 324 6 tabs tab NNS cord-005646-xhx9pzhj 324 7 to to IN cord-005646-xhx9pzhj 324 8 clinical clinical JJ cord-005646-xhx9pzhj 324 9 practice practice NN cord-005646-xhx9pzhj 324 10 . . . cord-005646-xhx9pzhj 325 1 It -PRON- PRP cord-005646-xhx9pzhj 325 2 is be VBZ cord-005646-xhx9pzhj 325 3 simple simple JJ cord-005646-xhx9pzhj 325 4 , , , cord-005646-xhx9pzhj 325 5 could could MD cord-005646-xhx9pzhj 325 6 be be VB cord-005646-xhx9pzhj 325 7 performed perform VBN cord-005646-xhx9pzhj 325 8 anywhere anywhere RB cord-005646-xhx9pzhj 325 9 , , , cord-005646-xhx9pzhj 325 10 cheaper cheap JJR cord-005646-xhx9pzhj 325 11 than than IN cord-005646-xhx9pzhj 325 12 TLV TLV NNP cord-005646-xhx9pzhj 325 13 . . . cord-005646-xhx9pzhj 326 1 However however RB cord-005646-xhx9pzhj 326 2 , , , cord-005646-xhx9pzhj 326 3 because because IN cord-005646-xhx9pzhj 326 4 Liquivent Liquivent NNP cord-005646-xhx9pzhj 326 5 -Perflubren -Perflubren NNP cord-005646-xhx9pzhj 326 6 ( ( -LRB- cord-005646-xhx9pzhj 326 7 Aliance Aliance NNP cord-005646-xhx9pzhj 326 8 Pharmaceutical Pharmaceutical NNP cord-005646-xhx9pzhj 326 9 ) ) -RRB- cord-005646-xhx9pzhj 326 10 is be VBZ cord-005646-xhx9pzhj 326 11 not not RB cord-005646-xhx9pzhj 326 12 available available JJ cord-005646-xhx9pzhj 326 13 in in IN cord-005646-xhx9pzhj 326 14 Europe Europe NNP cord-005646-xhx9pzhj 326 15 , , , cord-005646-xhx9pzhj 326 16 RM RM NNP cord-005646-xhx9pzhj 326 17 101 101 CD cord-005646-xhx9pzhj 326 18 of of IN cord-005646-xhx9pzhj 326 19 82 82 CD cord-005646-xhx9pzhj 326 20 ( ( -LRB- cord-005646-xhx9pzhj 326 21 Mitenti Mitenti NNP cord-005646-xhx9pzhj 326 22 , , , cord-005646-xhx9pzhj 326 23 Italy Italy NNP cord-005646-xhx9pzhj 326 24 ) ) -RRB- cord-005646-xhx9pzhj 326 25 is be VBZ cord-005646-xhx9pzhj 326 26 the the DT cord-005646-xhx9pzhj 326 27 only only JJ cord-005646-xhx9pzhj 326 28 solution solution NN cord-005646-xhx9pzhj 326 29 , , , cord-005646-xhx9pzhj 326 30 which which WDT cord-005646-xhx9pzhj 326 31 could could MD cord-005646-xhx9pzhj 326 32 be be VB cord-005646-xhx9pzhj 326 33 currently currently RB cord-005646-xhx9pzhj 326 34 used use VBN cord-005646-xhx9pzhj 326 35 here here RB cord-005646-xhx9pzhj 326 36 . . . cord-005646-xhx9pzhj 327 1 Before before IN cord-005646-xhx9pzhj 327 2 the the DT cord-005646-xhx9pzhj 327 3 widespread widespread JJ cord-005646-xhx9pzhj 327 4 use use NN cord-005646-xhx9pzhj 327 5 of of IN cord-005646-xhx9pzhj 327 6 PAGE page NN cord-005646-xhx9pzhj 327 7 in in IN cord-005646-xhx9pzhj 327 8 clinics clinic NNS cord-005646-xhx9pzhj 327 9 , , , cord-005646-xhx9pzhj 327 10 liquid liquid JJ cord-005646-xhx9pzhj 327 11 network network NN cord-005646-xhx9pzhj 327 12 among among IN cord-005646-xhx9pzhj 327 13 most most JJS cord-005646-xhx9pzhj 327 14 NICUs nicu NNS cord-005646-xhx9pzhj 327 15 and and CC cord-005646-xhx9pzhj 327 16 PICUs PICUs NNP cord-005646-xhx9pzhj 327 17 must must MD cord-005646-xhx9pzhj 327 18 be be VB cord-005646-xhx9pzhj 327 19 built build VBN cord-005646-xhx9pzhj 327 20 up up RP cord-005646-xhx9pzhj 327 21 , , , cord-005646-xhx9pzhj 327 22 the the DT cord-005646-xhx9pzhj 327 23 criteria criterion NNS cord-005646-xhx9pzhj 327 24 for for IN cord-005646-xhx9pzhj 327 25 PAGE page NN cord-005646-xhx9pzhj 327 26 must must MD cord-005646-xhx9pzhj 327 27 be be VB cord-005646-xhx9pzhj 327 28 defined define VBN cord-005646-xhx9pzhj 327 29 and and CC cord-005646-xhx9pzhj 327 30 ethinal ethinal JJ cord-005646-xhx9pzhj 327 31 - - HYPH cord-005646-xhx9pzhj 327 32 legal legal JJ cord-005646-xhx9pzhj 327 33 problems problem NNS cord-005646-xhx9pzhj 327 34 resolved resolve VBN cord-005646-xhx9pzhj 327 35 as as RB cord-005646-xhx9pzhj 327 36 well well RB cord-005646-xhx9pzhj 327 37 . . . cord-005646-xhx9pzhj 328 1 After after IN cord-005646-xhx9pzhj 328 2 resolution resolution NN cord-005646-xhx9pzhj 328 3 of of IN cord-005646-xhx9pzhj 328 4 these these DT cord-005646-xhx9pzhj 328 5 particular particular JJ cord-005646-xhx9pzhj 328 6 problems problem NNS cord-005646-xhx9pzhj 328 7 PAGE page NN cord-005646-xhx9pzhj 328 8 can can MD cord-005646-xhx9pzhj 328 9 be be VB cord-005646-xhx9pzhj 328 10 life life NN cord-005646-xhx9pzhj 328 11 saving save VBG cord-005646-xhx9pzhj 328 12 procedure procedure NN cord-005646-xhx9pzhj 328 13 for for IN cord-005646-xhx9pzhj 328 14 very very RB cord-005646-xhx9pzhj 328 15 special special JJ cord-005646-xhx9pzhj 328 16 part part NN cord-005646-xhx9pzhj 328 17 of of IN cord-005646-xhx9pzhj 328 18 critically critically RB cord-005646-xhx9pzhj 328 19 ill ill JJ cord-005646-xhx9pzhj 328 20 newborns newborn NNS cord-005646-xhx9pzhj 328 21 end end VBP cord-005646-xhx9pzhj 328 22 infants infant NNS cord-005646-xhx9pzhj 328 23 . . . cord-005646-xhx9pzhj 329 1 Catherine Catherine NNP cord-005646-xhx9pzhj 329 2 Caronia Caronia NNP cord-005646-xhx9pzhj 329 3 , , , cord-005646-xhx9pzhj 329 4 Peter Peter NNP cord-005646-xhx9pzhj 329 5 Silver Silver NNP cord-005646-xhx9pzhj 329 6 , , , cord-005646-xhx9pzhj 329 7 Laura Laura NNP cord-005646-xhx9pzhj 329 8 Nimkoff Nimkoff NNP cord-005646-xhx9pzhj 329 9 , , , cord-005646-xhx9pzhj 329 10 Cad Cad NNP cord-005646-xhx9pzhj 329 11 Quinn Quinn NNP cord-005646-xhx9pzhj 329 12 , , , cord-005646-xhx9pzhj 329 13 Jack Jack NNP cord-005646-xhx9pzhj 329 14 Gorvoy Gorvoy NNP cord-005646-xhx9pzhj 329 15 , , , cord-005646-xhx9pzhj 329 16 and and CC cord-005646-xhx9pzhj 329 17 Mayer Mayer NNP cord-005646-xhx9pzhj 329 18 SaN. SaN. NNP cord-005646-xhx9pzhj 329 19 Division Division NNP cord-005646-xhx9pzhj 329 20 of of IN cord-005646-xhx9pzhj 329 21 Pediartic Pediartic NNP cord-005646-xhx9pzhj 329 22 Critical Critical NNP cord-005646-xhx9pzhj 329 23 Care Care NNP cord-005646-xhx9pzhj 329 24 , , , cord-005646-xhx9pzhj 329 25 Medici Medici NNP cord-005646-xhx9pzhj 329 26 , , , cord-005646-xhx9pzhj 329 27 , , , cord-005646-xhx9pzhj 329 28 Schneider Schneider NNP cord-005646-xhx9pzhj 329 29 Children Children NNP cord-005646-xhx9pzhj 329 30 's 's POS cord-005646-xhx9pzhj 329 31 Hospital Hospital NNP cord-005646-xhx9pzhj 329 32 , , , cord-005646-xhx9pzhj 329 33 New New NNP cord-005646-xhx9pzhj 329 34 Hyde Hyde NNP cord-005646-xhx9pzhj 329 35 Park Park NNP cord-005646-xhx9pzhj 329 36 , , , cord-005646-xhx9pzhj 329 37 NY NY NNP cord-005646-xhx9pzhj 329 38 11040 11040 CD cord-005646-xhx9pzhj 329 39 , , , cord-005646-xhx9pzhj 329 40 Imroduetiun Imroduetiun NNP cord-005646-xhx9pzhj 329 41 : : : cord-005646-xhx9pzhj 329 42 Cystic cystic JJ cord-005646-xhx9pzhj 329 43 fibrosis fibrosis NN cord-005646-xhx9pzhj 329 44 ( ( -LRB- cord-005646-xhx9pzhj 329 45 CF CF NNP cord-005646-xhx9pzhj 329 46 ) ) -RRB- cord-005646-xhx9pzhj 329 47 patients patient NNS cord-005646-xhx9pzhj 329 48 awaiting await VBG cord-005646-xhx9pzhj 329 49 lung lung NN cord-005646-xhx9pzhj 329 50 transplantation transplantation NN cord-005646-xhx9pzhj 329 51 present present VBP cord-005646-xhx9pzhj 329 52 a a DT cord-005646-xhx9pzhj 329 53 therapeutic therapeutic JJ cord-005646-xhx9pzhj 329 54 dilenuna dilenuna NN cord-005646-xhx9pzhj 330 1 when when WRB cord-005646-xhx9pzhj 330 2 severe severe JJ cord-005646-xhx9pzhj 330 3 respir respir NNP cord-005646-xhx9pzhj 330 4 , , , cord-005646-xhx9pzhj 330 5 aory aory NNP cord-005646-xhx9pzhj 330 6 decompemalion decompemalion NNP cord-005646-xhx9pzhj 330 7 occurs occur VBZ cord-005646-xhx9pzhj 330 8 , , , cord-005646-xhx9pzhj 330 9 Endotracheal Endotracheal NNP cord-005646-xhx9pzhj 330 10 intubation intubation NN cord-005646-xhx9pzhj 330 11 and and CC cord-005646-xhx9pzhj 330 12 mechanical mechanical JJ cord-005646-xhx9pzhj 330 13 ventilation ventilation NN cord-005646-xhx9pzhj 330 14 is be VBZ cord-005646-xhx9pzhj 330 15 known know VBN cord-005646-xhx9pzhj 330 16 to to TO cord-005646-xhx9pzhj 330 17 have have VB cord-005646-xhx9pzhj 330 18 no no DT cord-005646-xhx9pzhj 330 19 long long JJ cord-005646-xhx9pzhj 330 20 term term NN cord-005646-xhx9pzhj 330 21 benefits benefit NNS cord-005646-xhx9pzhj 330 22 and and CC cord-005646-xhx9pzhj 330 23 is be VBZ cord-005646-xhx9pzhj 330 24 associated associate VBN cord-005646-xhx9pzhj 330 25 with with IN cord-005646-xhx9pzhj 330 26 high high JJ cord-005646-xhx9pzhj 330 27 morbidity morbidity NN cord-005646-xhx9pzhj 330 28 and and CC cord-005646-xhx9pzhj 330 29 mortality mortality NN cord-005646-xhx9pzhj 330 30 . . . cord-005646-xhx9pzhj 331 1 Noninvasive noninvasive JJ cord-005646-xhx9pzhj 331 2 respiratory respiratory JJ cord-005646-xhx9pzhj 331 3 support support NN cord-005646-xhx9pzhj 331 4 appears appear VBZ cord-005646-xhx9pzhj 331 5 to to TO cord-005646-xhx9pzhj 331 6 be be VB cord-005646-xhx9pzhj 331 7 a a DT cord-005646-xhx9pzhj 331 8 beneficial beneficial JJ cord-005646-xhx9pzhj 331 9 alternative alternative NN cord-005646-xhx9pzhj 331 10 . . . cord-005646-xhx9pzhj 332 1 Methods method NNS cord-005646-xhx9pzhj 332 2 : : : cord-005646-xhx9pzhj 332 3 We -PRON- PRP cord-005646-xhx9pzhj 332 4 instituted institute VBD cord-005646-xhx9pzhj 332 5 BIPAP BIPAP NNP cord-005646-xhx9pzhj 332 6 ( ( -LRB- cord-005646-xhx9pzhj 332 7 Respironics Respironics NNP cord-005646-xhx9pzhj 332 8 , , , cord-005646-xhx9pzhj 332 9 Inc Inc NNP cord-005646-xhx9pzhj 332 10 , , , cord-005646-xhx9pzhj 332 11 , , , cord-005646-xhx9pzhj 332 12 Murrayville Murrayville NNP cord-005646-xhx9pzhj 332 13 , , , cord-005646-xhx9pzhj 332 14 PA PA NNP cord-005646-xhx9pzhj 332 15 ) ) -RRB- cord-005646-xhx9pzhj 332 16 in in IN cord-005646-xhx9pzhj 332 17 9 9 CD cord-005646-xhx9pzhj 332 18 end end NN cord-005646-xhx9pzhj 332 19 - - HYPH cord-005646-xhx9pzhj 332 20 stage stage NN cord-005646-xhx9pzhj 332 21 CF cf NN cord-005646-xhx9pzhj 332 22 patients patient NNS cord-005646-xhx9pzhj 332 23 who who WP cord-005646-xhx9pzhj 332 24 were be VBD cord-005646-xhx9pzhj 332 25 admitted admit VBN cord-005646-xhx9pzhj 332 26 to to IN cord-005646-xhx9pzhj 332 27 the the DT cord-005646-xhx9pzhj 332 28 Pediatric Pediatric NNP cord-005646-xhx9pzhj 332 29 ICU ICU NNP cord-005646-xhx9pzhj 332 30 with with IN cord-005646-xhx9pzhj 332 31 severe severe JJ cord-005646-xhx9pzhj 332 32 respiratory respiratory JJ cord-005646-xhx9pzhj 332 33 decompeusation decompeusation NN cord-005646-xhx9pzhj 332 34 . . . cord-005646-xhx9pzhj 333 1 All all DT cord-005646-xhx9pzhj 333 2 patients patient NNS cord-005646-xhx9pzhj 333 3 were be VBD cord-005646-xhx9pzhj 333 4 awaiting await VBG cord-005646-xhx9pzhj 333 5 tung tung NNP cord-005646-xhx9pzhj 333 6 transplantation transplantation NN cord-005646-xhx9pzhj 333 7 . . . cord-005646-xhx9pzhj 334 1 After after IN cord-005646-xhx9pzhj 334 2 a a DT cord-005646-xhx9pzhj 334 3 control control NN cord-005646-xhx9pzhj 334 4 period period NN cord-005646-xhx9pzhj 334 5 , , , cord-005646-xhx9pzhj 334 6 BIPAP BIPAP NNP cord-005646-xhx9pzhj 334 7 was be VBD cord-005646-xhx9pzhj 334 8 applied apply VBN cord-005646-xhx9pzhj 334 9 via via IN cord-005646-xhx9pzhj 334 10 a a DT cord-005646-xhx9pzhj 334 11 tight tight JJ cord-005646-xhx9pzhj 334 12 fitting fitting JJ cord-005646-xhx9pzhj 334 13 nasal nasal NN cord-005646-xhx9pzhj 334 14 or or CC cord-005646-xhx9pzhj 334 15 facial facial JJ cord-005646-xhx9pzhj 334 16 mask mask NN cord-005646-xhx9pzhj 334 17 , , , cord-005646-xhx9pzhj 334 18 using use VBG cord-005646-xhx9pzhj 334 19 the the DT cord-005646-xhx9pzhj 334 20 spo spo NNP cord-005646-xhx9pzhj 334 21 ~ ~ NFP cord-005646-xhx9pzhj 334 22 aneous aneous JJ cord-005646-xhx9pzhj 334 23 breathing breathing NN cord-005646-xhx9pzhj 334 24 mode mode NN cord-005646-xhx9pzhj 334 25 , , , cord-005646-xhx9pzhj 334 26 Expiratory Expiratory NNP cord-005646-xhx9pzhj 334 27 pressures pressure NNS cord-005646-xhx9pzhj 334 28 were be VBD cord-005646-xhx9pzhj 334 29 set set VBN cord-005646-xhx9pzhj 334 30 at at IN cord-005646-xhx9pzhj 334 31 4 4 CD cord-005646-xhx9pzhj 334 32 - - SYM cord-005646-xhx9pzhj 334 33 8 8 CD cord-005646-xhx9pzhj 334 34 cm cm NN cord-005646-xhx9pzhj 335 1 HHzO. HHzO. NNP cord-005646-xhx9pzhj 335 2 Inspiratory Inspiratory NNP cord-005646-xhx9pzhj 335 3 pressures pressure NNS cord-005646-xhx9pzhj 335 4 were be VBD cord-005646-xhx9pzhj 335 5 started start VBN cord-005646-xhx9pzhj 335 6 at at IN cord-005646-xhx9pzhj 335 7 8 8 CD cord-005646-xhx9pzhj 335 8 cm cm NNS cord-005646-xhx9pzhj 336 1 ~I ~I NFP cord-005646-xhx9pzhj 337 1 O o UH cord-005646-xhx9pzhj 337 2 and and CC cord-005646-xhx9pzhj 337 3 increased increase VBD cord-005646-xhx9pzhj 337 4 in in IN cord-005646-xhx9pzhj 337 5 2 2 CD cord-005646-xhx9pzhj 337 6 cm cm NN cord-005646-xhx9pzhj 338 1 I -PRON- PRP cord-005646-xhx9pzhj 338 2 - - HYPH cord-005646-xhx9pzhj 338 3 I20 I20 NNP cord-005646-xhx9pzhj 338 4 increments increment NNS cord-005646-xhx9pzhj 338 5 until until IN cord-005646-xhx9pzhj 338 6 the the DT cord-005646-xhx9pzhj 338 7 patient patient NN cord-005646-xhx9pzhj 338 8 's 's POS cord-005646-xhx9pzhj 338 9 respiratory respiratory JJ cord-005646-xhx9pzhj 338 10 comfort comfort NN cord-005646-xhx9pzhj 338 11 was be VBD cord-005646-xhx9pzhj 338 12 achieved achieve VBN cord-005646-xhx9pzhj 338 13 and and CC cord-005646-xhx9pzhj 338 14 substantiated substantiate VBN cord-005646-xhx9pzhj 338 15 by by IN cord-005646-xhx9pzhj 338 16 non non JJ cord-005646-xhx9pzhj 338 17 - - JJ cord-005646-xhx9pzhj 338 18 invasive invasive JJ cord-005646-xhx9pzhj 338 19 monitoring monitoring NN cord-005646-xhx9pzhj 338 20 . . . cord-005646-xhx9pzhj 339 1 Patients patient NNS cord-005646-xhx9pzhj 339 2 were be VBD cord-005646-xhx9pzhj 339 3 instructed instruct VBN cord-005646-xhx9pzhj 339 4 to to TO cord-005646-xhx9pzhj 339 5 use use VB cord-005646-xhx9pzhj 339 6 BIPAP BIPAP NNP cord-005646-xhx9pzhj 339 7 during during IN cord-005646-xhx9pzhj 339 8 night night NN cord-005646-xhx9pzhj 339 9 sleep sleep NN cord-005646-xhx9pzhj 339 10 and and CC cord-005646-xhx9pzhj 339 11 whenever whenever WRB cord-005646-xhx9pzhj 339 12 subjectively subjectively RB cord-005646-xhx9pzhj 339 13 required require VBN cord-005646-xhx9pzhj 339 14 , , , cord-005646-xhx9pzhj 339 15 Data datum NNS cord-005646-xhx9pzhj 339 16 are be VBP cord-005646-xhx9pzhj 339 17 reported report VBN cord-005646-xhx9pzhj 339 18 as as IN cord-005646-xhx9pzhj 339 19 mean mean JJ cord-005646-xhx9pzhj 339 20 _ _ NNP cord-005646-xhx9pzhj 340 1 + + CC cord-005646-xhx9pzhj 341 1 S.D. S.D. NNP cord-005646-xhx9pzhj 341 2 Results result NNS cord-005646-xhx9pzhj 341 3 : : : cord-005646-xhx9pzhj 342 1 All all DT cord-005646-xhx9pzhj 342 2 9 9 CD cord-005646-xhx9pzhj 342 3 patiems patiem NNS cord-005646-xhx9pzhj 342 4 utilized utilize VBD cord-005646-xhx9pzhj 342 5 nocturnal nocturnal JJ cord-005646-xhx9pzhj 342 6 BIPAP BIPAP NNP cord-005646-xhx9pzhj 342 7 for for IN cord-005646-xhx9pzhj 342 8 6 6 CD cord-005646-xhx9pzhj 342 9 - - SYM cord-005646-xhx9pzhj 342 10 10 10 CD cord-005646-xhx9pzhj 342 11 hours hour NNS cord-005646-xhx9pzhj 342 12 / / SYM cord-005646-xhx9pzhj 342 13 day day NN cord-005646-xhx9pzhj 342 14 during during IN cord-005646-xhx9pzhj 342 15 a a DT cord-005646-xhx9pzhj 342 16 follow follow NN cord-005646-xhx9pzhj 342 17 - - HYPH cord-005646-xhx9pzhj 342 18 up up NN cord-005646-xhx9pzhj 342 19 period period NN cord-005646-xhx9pzhj 342 20 of of IN cord-005646-xhx9pzhj 342 21 2 2 CD cord-005646-xhx9pzhj 342 22 - - SYM cord-005646-xhx9pzhj 342 23 19 19 CD cord-005646-xhx9pzhj 342 24 months month NNS cord-005646-xhx9pzhj 342 25 . . . cord-005646-xhx9pzhj 343 1 Compared compare VBN cord-005646-xhx9pzhj 343 2 to to IN cord-005646-xhx9pzhj 343 3 their -PRON- PRP$ cord-005646-xhx9pzhj 343 4 pre pre JJ cord-005646-xhx9pzhj 343 5 - - JJ cord-005646-xhx9pzhj 343 6 BIPAP bipap JJ cord-005646-xhx9pzhj 343 7 status status NN cord-005646-xhx9pzhj 343 8 , , , cord-005646-xhx9pzhj 343 9 the the DT cord-005646-xhx9pzhj 343 10 patiems patiem NNS cord-005646-xhx9pzhj 343 11 ' ' POS cord-005646-xhx9pzhj 343 12 oxygen oxygen NN cord-005646-xhx9pzhj 343 13 requirement requirement NN cord-005646-xhx9pzhj 343 14 and and CC cord-005646-xhx9pzhj 343 15 respiratory respiratory JJ cord-005646-xhx9pzhj 343 16 rate rate NN cord-005646-xhx9pzhj 343 17 both both DT cord-005646-xhx9pzhj 343 18 Oz~ Oz~ NNP cord-005646-xhx9pzhj 343 19 Cundusion Cundusion NNP cord-005646-xhx9pzhj 343 20 : : : cord-005646-xhx9pzhj 343 21 BIPAP BIPAP NNP cord-005646-xhx9pzhj 343 22 tl tl NNP cord-005646-xhx9pzhj 343 23 ~ ~ NFP cord-005646-xhx9pzhj 343 24 rapy rapy NNP cord-005646-xhx9pzhj 343 25 improves improve VBZ cord-005646-xhx9pzhj 343 26 the the DT cord-005646-xhx9pzhj 343 27 respiratory respiratory JJ cord-005646-xhx9pzhj 343 28 status status NN cord-005646-xhx9pzhj 343 29 of of IN cord-005646-xhx9pzhj 343 30 decompeusatir!g decompeusatir!g JJ cord-005646-xhx9pzhj 343 31 end end NN cord-005646-xhx9pzhj 343 32 - - HYPH cord-005646-xhx9pzhj 343 33 stage stage NN cord-005646-xhx9pzhj 343 34 CF cf NN cord-005646-xhx9pzhj 343 35 paacnts paacnt NNS cord-005646-xhx9pzhj 343 36 . . . cord-005646-xhx9pzhj 344 1 It -PRON- PRP cord-005646-xhx9pzhj 344 2 is be VBZ cord-005646-xhx9pzhj 344 3 well well RB cord-005646-xhx9pzhj 344 4 tolerated tolerate VBN cord-005646-xhx9pzhj 344 5 for for IN cord-005646-xhx9pzhj 344 6 long long JJ cord-005646-xhx9pzhj 344 7 term term NN cord-005646-xhx9pzhj 344 8 use use NN cord-005646-xhx9pzhj 344 9 at at IN cord-005646-xhx9pzhj 344 10 home home NN cord-005646-xhx9pzhj 344 11 , , , cord-005646-xhx9pzhj 344 12 and and CC cord-005646-xhx9pzhj 344 13 provides provide VBZ cord-005646-xhx9pzhj 344 14 an an DT cord-005646-xhx9pzhj 344 15 extended extended JJ cord-005646-xhx9pzhj 344 16 period period NN cord-005646-xhx9pzhj 344 17 of of IN cord-005646-xhx9pzhj 344 18 respiratory respiratory JJ cord-005646-xhx9pzhj 344 19 comfort comfort NN cord-005646-xhx9pzhj 344 20 and and CC cord-005646-xhx9pzhj 344 21 stability stability NN cord-005646-xhx9pzhj 344 22 for for IN cord-005646-xhx9pzhj 344 23 CF cf NN cord-005646-xhx9pzhj 344 24 patients patient NNS cord-005646-xhx9pzhj 344 25 awaiting await VBG cord-005646-xhx9pzhj 344 26 lung lung NN cord-005646-xhx9pzhj 344 27 transplantation transplantation NN cord-005646-xhx9pzhj 344 28 . . . cord-005646-xhx9pzhj 345 1 L. L. NNP cord-005646-xhx9pzhj 345 2 Bindl Bindl NNP cord-005646-xhx9pzhj 345 3 * * NFP cord-005646-xhx9pzhj 345 4 , , , cord-005646-xhx9pzhj 345 5 G. G. NNP cord-005646-xhx9pzhj 345 6 Kiihl Kiihl NNP cord-005646-xhx9pzhj 346 1 * * NFP cord-005646-xhx9pzhj 346 2 * * NFP cord-005646-xhx9pzhj 346 3 , , , cord-005646-xhx9pzhj 346 4 P. P. NNP cord-005646-xhx9pzhj 346 5 Lasch Lasch NNP cord-005646-xhx9pzhj 347 1 * * NFP cord-005646-xhx9pzhj 347 2 * * NFP cord-005646-xhx9pzhj 347 3 * * NFP cord-005646-xhx9pzhj 347 4 , , , cord-005646-xhx9pzhj 347 5 Appel Appel NNP cord-005646-xhx9pzhj 348 1 * * NFP cord-005646-xhx9pzhj 348 2 * * NFP cord-005646-xhx9pzhj 348 3 , , , cord-005646-xhx9pzhj 348 4 J.M611er J.M611er NNP cord-005646-xhx9pzhj 348 5 * * NFP cord-005646-xhx9pzhj 348 6 * * NFP cord-005646-xhx9pzhj 348 7 * * NFP cord-005646-xhx9pzhj 348 8 * * NFP cord-005646-xhx9pzhj 348 9 and and CC cord-005646-xhx9pzhj 348 10 the the DT cord-005646-xhx9pzhj 348 11 " " `` cord-005646-xhx9pzhj 348 12 Arbeitsgemeinschaft Arbeitsgemeinschaft NNP cord-005646-xhx9pzhj 348 13 ARDS ARDS NNP cord-005646-xhx9pzhj 348 14 i -PRON- PRP cord-005646-xhx9pzhj 348 15 m be VBP cord-005646-xhx9pzhj 348 16 Kindesalter Kindesalter NNP cord-005646-xhx9pzhj 348 17 " " `` cord-005646-xhx9pzhj 348 18 Background Background NNP cord-005646-xhx9pzhj 348 19 Acute acute JJ cord-005646-xhx9pzhj 348 20 respiratory respiratory JJ cord-005646-xhx9pzhj 348 21 distress distress NN cord-005646-xhx9pzhj 348 22 syndrome syndrome NN cord-005646-xhx9pzhj 348 23 ( ( -LRB- cord-005646-xhx9pzhj 348 24 ARDS ARDS NNP cord-005646-xhx9pzhj 348 25 ) ) -RRB- cord-005646-xhx9pzhj 348 26 is be VBZ cord-005646-xhx9pzhj 348 27 a a DT cord-005646-xhx9pzhj 348 28 therapeutic therapeutic JJ cord-005646-xhx9pzhj 348 29 challenge challenge NN cord-005646-xhx9pzhj 348 30 in in IN cord-005646-xhx9pzhj 348 31 pediatric pediatric JJ cord-005646-xhx9pzhj 348 32 intensive intensive JJ cord-005646-xhx9pzhj 348 33 care care NN cord-005646-xhx9pzhj 348 34 in in IN cord-005646-xhx9pzhj 348 35 view view NN cord-005646-xhx9pzhj 348 36 of of IN cord-005646-xhx9pzhj 348 37 the the DT cord-005646-xhx9pzhj 348 38 high high JJ cord-005646-xhx9pzhj 348 39 mortality mortality NN cord-005646-xhx9pzhj 348 40 , , , cord-005646-xhx9pzhj 348 41 In in IN cord-005646-xhx9pzhj 348 42 1992 1992 CD cord-005646-xhx9pzhj 348 43 about about IN cord-005646-xhx9pzhj 348 44 50 50 CD cord-005646-xhx9pzhj 348 45 German german JJ cord-005646-xhx9pzhj 348 46 paediatlic paediatlic NN cord-005646-xhx9pzhj 348 47 hospitals hospital NNS cord-005646-xhx9pzhj 348 48 founded found VBD cord-005646-xhx9pzhj 348 49 a a DT cord-005646-xhx9pzhj 348 50 working work VBG cord-005646-xhx9pzhj 348 51 group group NN cord-005646-xhx9pzhj 348 52 aiming aim VBG cord-005646-xhx9pzhj 348 53 on on IN cord-005646-xhx9pzhj 348 54 collaborative collaborative JJ cord-005646-xhx9pzhj 348 55 clinical clinical JJ cord-005646-xhx9pzhj 348 56 research research NN cord-005646-xhx9pzhj 348 57 in in IN cord-005646-xhx9pzhj 348 58 this this DT cord-005646-xhx9pzhj 348 59 field field NN cord-005646-xhx9pzhj 348 60 . . . cord-005646-xhx9pzhj 349 1 Aims aim NNS cord-005646-xhx9pzhj 349 2 and and CC cord-005646-xhx9pzhj 349 3 methods method NNS cord-005646-xhx9pzhj 350 1 The the DT cord-005646-xhx9pzhj 350 2 aim aim NN cord-005646-xhx9pzhj 350 3 of of IN cord-005646-xhx9pzhj 350 4 both both CC cord-005646-xhx9pzhj 350 5 a a DT cord-005646-xhx9pzhj 350 6 prospective prospective JJ cord-005646-xhx9pzhj 350 7 and and CC cord-005646-xhx9pzhj 350 8 retrospective retrospective JJ cord-005646-xhx9pzhj 350 9 survey survey NN cord-005646-xhx9pzhj 350 10 conducted conduct VBN cord-005646-xhx9pzhj 350 11 in in IN cord-005646-xhx9pzhj 350 12 German german JJ cord-005646-xhx9pzhj 350 13 pediatric pediatric JJ cord-005646-xhx9pzhj 350 14 intensive intensive JJ cord-005646-xhx9pzhj 350 15 care care NN cord-005646-xhx9pzhj 350 16 units unit NNS cord-005646-xhx9pzhj 350 17 in in IN cord-005646-xhx9pzhj 350 18 1993 1993 CD cord-005646-xhx9pzhj 350 19 was be VBD cord-005646-xhx9pzhj 350 20 to to TO cord-005646-xhx9pzhj 350 21 accumulate accumulate VB cord-005646-xhx9pzhj 350 22 data datum NNS cord-005646-xhx9pzhj 350 23 on on IN cord-005646-xhx9pzhj 350 24 the the DT cord-005646-xhx9pzhj 350 25 epidemiology epidemiology NN cord-005646-xhx9pzhj 350 26 , , , cord-005646-xhx9pzhj 350 27 risk risk NN cord-005646-xhx9pzhj 350 28 factors factor NNS cord-005646-xhx9pzhj 350 29 , , , cord-005646-xhx9pzhj 350 30 natural natural JJ cord-005646-xhx9pzhj 350 31 history history NN cord-005646-xhx9pzhj 350 32 and and CC cord-005646-xhx9pzhj 350 33 treatment treatment NN cord-005646-xhx9pzhj 350 34 strategies strategy NNS cord-005646-xhx9pzhj 350 35 in in IN cord-005646-xhx9pzhj 350 36 a a DT cord-005646-xhx9pzhj 350 37 large large JJ cord-005646-xhx9pzhj 350 38 group group NN cord-005646-xhx9pzhj 350 39 of of IN cord-005646-xhx9pzhj 350 40 pediatric pediatric JJ cord-005646-xhx9pzhj 350 41 ARDS ARDS NNP cord-005646-xhx9pzhj 350 42 patients patient NNS cord-005646-xhx9pzhj 350 43 who who WP cord-005646-xhx9pzhj 350 44 were be VBD cord-005646-xhx9pzhj 350 45 treated treat VBN cord-005646-xhx9pzhj 350 46 in in IN cord-005646-xhx9pzhj 350 47 the the DT cord-005646-xhx9pzhj 350 48 tt tt NNP cord-005646-xhx9pzhj 350 49 ~ ~ NNP cord-005646-xhx9pzhj 350 50 ee ee NNP cord-005646-xhx9pzhj 350 51 year year NN cord-005646-xhx9pzhj 350 52 period period NN cord-005646-xhx9pzhj 350 53 from from IN cord-005646-xhx9pzhj 350 54 1991 1991 CD cord-005646-xhx9pzhj 350 55 to to IN cord-005646-xhx9pzhj 350 56 1993.All 1993.all CD cord-005646-xhx9pzhj 350 57 patients patient NNS cord-005646-xhx9pzhj 350 58 had have VBD cord-005646-xhx9pzhj 350 59 acute acute JJ cord-005646-xhx9pzhj 350 60 bilateral bilateral JJ cord-005646-xhx9pzhj 350 61 alveolar alveolar JJ cord-005646-xhx9pzhj 350 62 infiltration infiltration NN cord-005646-xhx9pzhj 350 63 of of IN cord-005646-xhx9pzhj 350 64 noncardiogenic noncardiogenic JJ cord-005646-xhx9pzhj 350 65 origin origin NN cord-005646-xhx9pzhj 350 66 and and CC cord-005646-xhx9pzhj 350 67 a a DT cord-005646-xhx9pzhj 350 68 pO2~iO2 pO2~iO2 NNP cord-005646-xhx9pzhj 350 69 ratio ratio NN cord-005646-xhx9pzhj 350 70 < < XX cord-005646-xhx9pzhj 350 71 150mmHg 150mmHg NNS cord-005646-xhx9pzhj 350 72 . . . cord-005646-xhx9pzhj 351 1 The the DT cord-005646-xhx9pzhj 351 2 influence influence NN cord-005646-xhx9pzhj 351 3 of of IN cord-005646-xhx9pzhj 351 4 sex sex NN cord-005646-xhx9pzhj 351 5 , , , cord-005646-xhx9pzhj 351 6 underlying underlie VBG cord-005646-xhx9pzhj 351 7 disease disease NN cord-005646-xhx9pzhj 351 8 and and CC cord-005646-xhx9pzhj 351 9 single single JJ cord-005646-xhx9pzhj 351 10 organ organ NN cord-005646-xhx9pzhj 351 11 failure failure NN cord-005646-xhx9pzhj 351 12 was be VBD cord-005646-xhx9pzhj 351 13 analyzed analyze VBN cord-005646-xhx9pzhj 351 14 using use VBG cord-005646-xhx9pzhj 351 15 the the DT cord-005646-xhx9pzhj 351 16 Fischer Fischer NNP cord-005646-xhx9pzhj 351 17 's 's POS cord-005646-xhx9pzhj 351 18 exact exact JJ cord-005646-xhx9pzhj 351 19 test test NN cord-005646-xhx9pzhj 351 20 , , , cord-005646-xhx9pzhj 351 21 the the DT cord-005646-xhx9pzhj 351 22 influence influence NN cord-005646-xhx9pzhj 351 23 of of IN cord-005646-xhx9pzhj 351 24 additional additional JJ cord-005646-xhx9pzhj 351 25 organ organ NN cord-005646-xhx9pzhj 351 26 failure failure NN cord-005646-xhx9pzhj 351 27 on on IN cord-005646-xhx9pzhj 351 28 mortality mortality NN cord-005646-xhx9pzhj 351 29 was be VBD cord-005646-xhx9pzhj 351 30 tested test VBN cord-005646-xhx9pzhj 351 31 with with IN cord-005646-xhx9pzhj 351 32 the the DT cord-005646-xhx9pzhj 351 33 Cochran Cochran NNP cord-005646-xhx9pzhj 351 34 - - HYPH cord-005646-xhx9pzhj 351 35 Mantel Mantel NNP cord-005646-xhx9pzhj 351 36 - - HYPH cord-005646-xhx9pzhj 351 37 Haenszet Haenszet NNP cord-005646-xhx9pzhj 351 38 statistics statistic NNS cord-005646-xhx9pzhj 351 39 . . . cord-005646-xhx9pzhj 352 1 Results result NNS cord-005646-xhx9pzhj 352 2 112 112 CD cord-005646-xhx9pzhj 352 3 patients patient NNS cord-005646-xhx9pzhj 352 4 were be VBD cord-005646-xhx9pzhj 352 5 reported report VBN cord-005646-xhx9pzhj 352 6 giving give VBG cord-005646-xhx9pzhj 352 7 an an DT cord-005646-xhx9pzhj 352 8 incidence incidence NN cord-005646-xhx9pzhj 352 9 of of IN cord-005646-xhx9pzhj 352 10 7 7 CD cord-005646-xhx9pzhj 352 11 cases case NNS cord-005646-xhx9pzhj 352 12 per per IN cord-005646-xhx9pzhj 352 13 1000 1000 CD cord-005646-xhx9pzhj 352 14 admissions admission NNS cord-005646-xhx9pzhj 352 15 to to IN cord-005646-xhx9pzhj 352 16 pediatric pediatric JJ cord-005646-xhx9pzhj 352 17 ICUs icu NNS cord-005646-xhx9pzhj 352 18 . . . cord-005646-xhx9pzhj 353 1 Median median JJ cord-005646-xhx9pzhj 353 2 age age NN cord-005646-xhx9pzhj 353 3 was be VBD cord-005646-xhx9pzhj 353 4 24 24 CD cord-005646-xhx9pzhj 353 5 month month NN cord-005646-xhx9pzhj 353 6 . . . cord-005646-xhx9pzhj 354 1 In in IN cord-005646-xhx9pzhj 354 2 43 43 CD cord-005646-xhx9pzhj 354 3 % % NN cord-005646-xhx9pzhj 354 4 of of IN cord-005646-xhx9pzhj 354 5 the the DT cord-005646-xhx9pzhj 354 6 cases case NNS cord-005646-xhx9pzhj 354 7 , , , cord-005646-xhx9pzhj 354 8 ARDS ARDS NNP cord-005646-xhx9pzhj 354 9 was be VBD cord-005646-xhx9pzhj 354 10 associated associate VBN cord-005646-xhx9pzhj 354 11 with with IN cord-005646-xhx9pzhj 354 12 a a DT cord-005646-xhx9pzhj 354 13 pulmonary pulmonary NN cord-005646-xhx9pzhj 354 14 , , , cord-005646-xhx9pzhj 354 15 in in IN cord-005646-xhx9pzhj 354 16 39 39 CD cord-005646-xhx9pzhj 354 17 % % NN cord-005646-xhx9pzhj 354 18 with with IN cord-005646-xhx9pzhj 354 19 a a DT cord-005646-xhx9pzhj 354 20 systemic systemic JJ cord-005646-xhx9pzhj 354 21 underlying underlie VBG cord-005646-xhx9pzhj 354 22 disease disease NN cord-005646-xhx9pzhj 354 23 . . . cord-005646-xhx9pzhj 355 1 In in IN cord-005646-xhx9pzhj 355 2 20 20 CD cord-005646-xhx9pzhj 355 3 % % NN cord-005646-xhx9pzhj 355 4 immunocompetence immunocompetence NN cord-005646-xhx9pzhj 355 5 was be VBD cord-005646-xhx9pzhj 355 6 impaired impair VBN cord-005646-xhx9pzhj 355 7 . . . cord-005646-xhx9pzhj 356 1 Mortality mortality NN cord-005646-xhx9pzhj 356 2 was be VBD cord-005646-xhx9pzhj 356 3 46 46 CD cord-005646-xhx9pzhj 356 4 % % NN cord-005646-xhx9pzhj 356 5 and and CC cord-005646-xhx9pzhj 356 6 not not RB cord-005646-xhx9pzhj 356 7 dependent dependent JJ cord-005646-xhx9pzhj 356 8 on on IN cord-005646-xhx9pzhj 356 9 age age NN cord-005646-xhx9pzhj 356 10 , , , cord-005646-xhx9pzhj 356 11 sex sex NN cord-005646-xhx9pzhj 356 12 and and CC cord-005646-xhx9pzhj 356 13 triggering trigger VBG cord-005646-xhx9pzhj 356 14 event event NN cord-005646-xhx9pzhj 356 15 . . . cord-005646-xhx9pzhj 357 1 The the DT cord-005646-xhx9pzhj 357 2 number number NN cord-005646-xhx9pzhj 357 3 of of IN cord-005646-xhx9pzhj 357 4 associated associate VBN cord-005646-xhx9pzhj 357 5 organ organ NN cord-005646-xhx9pzhj 357 6 failures failure NNS cord-005646-xhx9pzhj 357 7 , , , cord-005646-xhx9pzhj 357 8 however however RB cord-005646-xhx9pzhj 357 9 , , , cord-005646-xhx9pzhj 357 10 strongly strongly RB cord-005646-xhx9pzhj 357 11 influenced influence VBD cord-005646-xhx9pzhj 357 12 mortalib mortalib NNS cord-005646-xhx9pzhj 357 13 , , , cord-005646-xhx9pzhj 357 14 . . . cord-005646-xhx9pzhj 358 1 Mortafity Mortafity NNP cord-005646-xhx9pzhj 358 2 in in IN cord-005646-xhx9pzhj 358 3 immuno immuno JJ cord-005646-xhx9pzhj 358 4 - - HYPH cord-005646-xhx9pzhj 358 5 compromised compromise VBN cord-005646-xhx9pzhj 358 6 patients patient NNS cord-005646-xhx9pzhj 358 7 was be VBD cord-005646-xhx9pzhj 358 8 8 8 CD cord-005646-xhx9pzhj 358 9 t t NN cord-005646-xhx9pzhj 358 10 % % NN cord-005646-xhx9pzhj 358 11 . . . cord-005646-xhx9pzhj 359 1 The the DT cord-005646-xhx9pzhj 359 2 Analysis Analysis NNP cord-005646-xhx9pzhj 359 3 of of IN cord-005646-xhx9pzhj 359 4 treatment treatment NN cord-005646-xhx9pzhj 359 5 modalifies modalifie NNS cord-005646-xhx9pzhj 359 6 employed employ VBN cord-005646-xhx9pzhj 359 7 in in IN cord-005646-xhx9pzhj 359 8 the the DT cord-005646-xhx9pzhj 359 9 patients patient NNS cord-005646-xhx9pzhj 359 10 revealed reveal VBD cord-005646-xhx9pzhj 359 11 a a DT cord-005646-xhx9pzhj 359 12 lack lack NN cord-005646-xhx9pzhj 359 13 of of IN cord-005646-xhx9pzhj 359 14 uniform uniform JJ cord-005646-xhx9pzhj 359 15 therapeutic therapeutic JJ cord-005646-xhx9pzhj 359 16 strategies strategy NNS cord-005646-xhx9pzhj 359 17 . . . cord-005646-xhx9pzhj 360 1 On on IN cord-005646-xhx9pzhj 360 2 the the DT cord-005646-xhx9pzhj 360 3 other other JJ cord-005646-xhx9pzhj 360 4 hand hand NN cord-005646-xhx9pzhj 360 5 , , , cord-005646-xhx9pzhj 360 6 the the DT cord-005646-xhx9pzhj 360 7 patients patient NNS cord-005646-xhx9pzhj 360 8 were be VBD cord-005646-xhx9pzhj 360 9 exposed expose VBN cord-005646-xhx9pzhj 360 10 to to IN cord-005646-xhx9pzhj 360 11 interventions intervention NNS cord-005646-xhx9pzhj 360 12 not not RB cord-005646-xhx9pzhj 360 13 yet yet RB cord-005646-xhx9pzhj 360 14 supported support VBN cord-005646-xhx9pzhj 360 15 by by IN cord-005646-xhx9pzhj 360 16 controlled control VBN cord-005646-xhx9pzhj 360 17 trials trial NNS cord-005646-xhx9pzhj 360 18 . . . cord-005646-xhx9pzhj 361 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 362 1 The the DT cord-005646-xhx9pzhj 362 2 observation observation NN cord-005646-xhx9pzhj 362 3 of of IN cord-005646-xhx9pzhj 362 4 the the DT cord-005646-xhx9pzhj 362 5 lack lack NN cord-005646-xhx9pzhj 362 6 of of IN cord-005646-xhx9pzhj 362 7 uniform uniform JJ cord-005646-xhx9pzhj 362 8 treatment treatment NN cord-005646-xhx9pzhj 362 9 strategies strategy NNS cord-005646-xhx9pzhj 362 10 led lead VBD cord-005646-xhx9pzhj 362 11 to to IN cord-005646-xhx9pzhj 362 12 the the DT cord-005646-xhx9pzhj 362 13 elaboration elaboration NN cord-005646-xhx9pzhj 362 14 of of IN cord-005646-xhx9pzhj 362 15 recommendations recommendation NNS cord-005646-xhx9pzhj 362 16 on on IN cord-005646-xhx9pzhj 362 17 ventilator ventilator NN cord-005646-xhx9pzhj 362 18 therapy therapy NN cord-005646-xhx9pzhj 362 19 and and CC cord-005646-xhx9pzhj 362 20 patient patient JJ cord-005646-xhx9pzhj 362 21 monitoring monitoring NN cord-005646-xhx9pzhj 362 22 within within IN cord-005646-xhx9pzhj 362 23 the the DT cord-005646-xhx9pzhj 362 24 working work VBG cord-005646-xhx9pzhj 362 25 group group NN cord-005646-xhx9pzhj 362 26 . . . cord-005646-xhx9pzhj 363 1 The the DT cord-005646-xhx9pzhj 363 2 data datum NNS cord-005646-xhx9pzhj 363 3 gathered gather VBD cord-005646-xhx9pzhj 363 4 in in IN cord-005646-xhx9pzhj 363 5 this this DT cord-005646-xhx9pzhj 363 6 survey survey NN cord-005646-xhx9pzhj 363 7 provide provide VBP cord-005646-xhx9pzhj 363 8 the the DT cord-005646-xhx9pzhj 363 9 basis basis NN cord-005646-xhx9pzhj 363 10 for for IN cord-005646-xhx9pzhj 363 11 the the DT cord-005646-xhx9pzhj 363 12 design design NN cord-005646-xhx9pzhj 363 13 of of IN cord-005646-xhx9pzhj 363 14 prospective prospective JJ cord-005646-xhx9pzhj 363 15 multicenter multicenter JJ cord-005646-xhx9pzhj 363 16 studies study NNS cord-005646-xhx9pzhj 363 17 urgently urgently RB cord-005646-xhx9pzhj 363 18 needed need VBD cord-005646-xhx9pzhj 363 19 to to TO cord-005646-xhx9pzhj 363 20 evaluate evaluate VB cord-005646-xhx9pzhj 363 21 innovative innovative JJ cord-005646-xhx9pzhj 363 22 treatment treatment NN cord-005646-xhx9pzhj 363 23 modafities modafitie NNS cord-005646-xhx9pzhj 363 24 in in IN cord-005646-xhx9pzhj 363 25 pediatric pediatric JJ cord-005646-xhx9pzhj 363 26 ARDS ARDS NNP cord-005646-xhx9pzhj 363 27 . . . cord-005646-xhx9pzhj 364 1 Recurrent recurrent JJ cord-005646-xhx9pzhj 364 2 apnea apnea NN cord-005646-xhx9pzhj 364 3 and and CC cord-005646-xhx9pzhj 364 4 respiratory respiratory JJ cord-005646-xhx9pzhj 364 5 failnre failnre NN cord-005646-xhx9pzhj 364 6 due due JJ cord-005646-xhx9pzhj 364 7 to to IN cord-005646-xhx9pzhj 364 8 severe severe JJ cord-005646-xhx9pzhj 364 9 lower low JJR cord-005646-xhx9pzhj 364 10 respiratory respiratory JJ cord-005646-xhx9pzhj 364 11 tract tract NN cord-005646-xhx9pzhj 364 12 disorders disorder NNS cord-005646-xhx9pzhj 364 13 such such JJ cord-005646-xhx9pzhj 364 14 as as IN cord-005646-xhx9pzhj 364 15 bronchiolitis bronchiolitis NN cord-005646-xhx9pzhj 364 16 or or CC cord-005646-xhx9pzhj 364 17 pneumonia pneumonia NN cord-005646-xhx9pzhj 364 18 are be VBP cord-005646-xhx9pzhj 364 19 the the DT cord-005646-xhx9pzhj 364 20 most most RBS cord-005646-xhx9pzhj 364 21 common common JJ cord-005646-xhx9pzhj 364 22 reasons reason NNS cord-005646-xhx9pzhj 364 23 for for IN cord-005646-xhx9pzhj 364 24 mechanical mechanical JJ cord-005646-xhx9pzhj 364 25 ventilation ventilation NN cord-005646-xhx9pzhj 364 26 during during IN cord-005646-xhx9pzhj 364 27 respiratory respiratory JJ cord-005646-xhx9pzhj 364 28 syncytial syncytial JJ cord-005646-xhx9pzhj 364 29 virus virus NN cord-005646-xhx9pzhj 364 30 ( ( -LRB- cord-005646-xhx9pzhj 364 31 RSV RSV NNP cord-005646-xhx9pzhj 364 32 ) ) -RRB- cord-005646-xhx9pzhj 364 33 infection infection NN cord-005646-xhx9pzhj 364 34 . . . cord-005646-xhx9pzhj 365 1 Acute acute JJ cord-005646-xhx9pzhj 365 2 respiratory respiratory JJ cord-005646-xhx9pzhj 365 3 distress distress NN cord-005646-xhx9pzhj 365 4 syndrome syndrome NN cord-005646-xhx9pzhj 365 5 ( ( -LRB- cord-005646-xhx9pzhj 365 6 ARDS ARDS NNP cord-005646-xhx9pzhj 365 7 ) ) -RRB- cord-005646-xhx9pzhj 365 8 has have VBZ cord-005646-xhx9pzhj 365 9 been be VBN cord-005646-xhx9pzhj 365 10 described describe VBN cord-005646-xhx9pzhj 365 11 as as IN cord-005646-xhx9pzhj 365 12 a a DT cord-005646-xhx9pzhj 365 13 complication complication NN cord-005646-xhx9pzhj 365 14 of of IN cord-005646-xhx9pzhj 365 15 severe severe JJ cord-005646-xhx9pzhj 365 16 RSV RSV NNP cord-005646-xhx9pzhj 365 17 infectionJ infectionJ NNP cord-005646-xhx9pzhj 366 1 In in IN cord-005646-xhx9pzhj 366 2 contrast contrast NN cord-005646-xhx9pzhj 366 3 to to IN cord-005646-xhx9pzhj 366 4 the the DT cord-005646-xhx9pzhj 366 5 low low JJ cord-005646-xhx9pzhj 366 6 mortality mortality NN cord-005646-xhx9pzhj 366 7 rates rate NNS cord-005646-xhx9pzhj 366 8 associated associate VBN cord-005646-xhx9pzhj 366 9 with with IN cord-005646-xhx9pzhj 366 10 RSV RSV NNP cord-005646-xhx9pzhj 366 11 infection infection NN cord-005646-xhx9pzhj 366 12 ( ( -LRB- cord-005646-xhx9pzhj 366 13 < < NNP cord-005646-xhx9pzhj 366 14 5 5 CD cord-005646-xhx9pzhj 366 15 % % NN cord-005646-xhx9pzhj 366 16 ) ) -RRB- cord-005646-xhx9pzhj 366 17 , , , cord-005646-xhx9pzhj 366 18 mortality mortality NN cord-005646-xhx9pzhj 366 19 rates rate NNS cord-005646-xhx9pzhj 366 20 in in IN cord-005646-xhx9pzhj 366 21 the the DT cord-005646-xhx9pzhj 366 22 range range NN cord-005646-xhx9pzhj 366 23 of of IN cord-005646-xhx9pzhj 366 24 40 40 CD cord-005646-xhx9pzhj 366 25 - - SYM cord-005646-xhx9pzhj 366 26 70 70 CD cord-005646-xhx9pzhj 366 27 % % NN cord-005646-xhx9pzhj 366 28 have have VBP cord-005646-xhx9pzhj 366 29 been be VBN cord-005646-xhx9pzhj 366 30 reported report VBN cord-005646-xhx9pzhj 366 31 in in IN cord-005646-xhx9pzhj 366 32 pediatric pediatric JJ cord-005646-xhx9pzhj 366 33 patients patient NNS cord-005646-xhx9pzhj 366 34 with with IN cord-005646-xhx9pzhj 366 35 ARDS ARDS NNP cord-005646-xhx9pzhj 366 36 . . . cord-005646-xhx9pzhj 367 1 However however RB cord-005646-xhx9pzhj 367 2 , , , cord-005646-xhx9pzhj 367 3 studies study NNS cord-005646-xhx9pzhj 367 4 on on IN cord-005646-xhx9pzhj 367 5 ARDS ARDS NNP cord-005646-xhx9pzhj 367 6 are be VBP cord-005646-xhx9pzhj 367 7 usually usually RB cord-005646-xhx9pzhj 367 8 lumped lump VBN cord-005646-xhx9pzhj 367 9 in in IN cord-005646-xhx9pzhj 367 10 respect respect NN cord-005646-xhx9pzhj 367 11 to to IN cord-005646-xhx9pzhj 367 12 causation causation NN cord-005646-xhx9pzhj 367 13 and and CC cord-005646-xhx9pzhj 367 14 the the DT cord-005646-xhx9pzhj 367 15 disease disease NN cord-005646-xhx9pzhj 367 16 course course NN cord-005646-xhx9pzhj 367 17 of of IN cord-005646-xhx9pzhj 367 18 RSV RSV NNP cord-005646-xhx9pzhj 367 19 induced induce VBN cord-005646-xhx9pzhj 367 20 ARDS ARDS NNP cord-005646-xhx9pzhj 367 21 has have VBZ cord-005646-xhx9pzhj 367 22 not not RB cord-005646-xhx9pzhj 367 23 been be VBN cord-005646-xhx9pzhj 367 24 previously previously RB cord-005646-xhx9pzhj 367 25 studied study VBN cord-005646-xhx9pzhj 367 26 . . . cord-005646-xhx9pzhj 368 1 We -PRON- PRP cord-005646-xhx9pzhj 368 2 examined examine VBD cord-005646-xhx9pzhj 368 3 the the DT cord-005646-xhx9pzhj 368 4 lung lung NN cord-005646-xhx9pzhj 368 5 function function NN cord-005646-xhx9pzhj 368 6 abnormalities abnormality NNS cord-005646-xhx9pzhj 368 7 of of IN cord-005646-xhx9pzhj 368 8 37 37 CD cord-005646-xhx9pzhj 368 9 infants infant NNS cord-005646-xhx9pzhj 368 10 with with IN cord-005646-xhx9pzhj 368 11 RSV RSV NNP cord-005646-xhx9pzhj 368 12 induced induce VBD cord-005646-xhx9pzhj 368 13 respiratory respiratory JJ cord-005646-xhx9pzhj 368 14 failure failure NN cord-005646-xhx9pzhj 368 15 requiring require VBG cord-005646-xhx9pzhj 368 16 assisted assist VBN cord-005646-xhx9pzhj 368 17 ventilation ventilation NN cord-005646-xhx9pzhj 368 18 , , , cord-005646-xhx9pzhj 368 19 Measurements measurement NNS cord-005646-xhx9pzhj 368 20 included include VBD cord-005646-xhx9pzhj 368 21 respiratory respiratory JJ cord-005646-xhx9pzhj 368 22 mechanics mechanic NNS cord-005646-xhx9pzhj 368 23 , , , cord-005646-xhx9pzhj 368 24 maximal maximal JJ cord-005646-xhx9pzhj 368 25 expiratory expiratory JJ cord-005646-xhx9pzhj 368 26 flow flow NN cord-005646-xhx9pzhj 368 27 - - HYPH cord-005646-xhx9pzhj 368 28 volume volume NN cord-005646-xhx9pzhj 368 29 curves curve NNS cord-005646-xhx9pzhj 368 30 and and CC cord-005646-xhx9pzhj 368 31 lung lung NN cord-005646-xhx9pzhj 368 32 volumes volume NNS cord-005646-xhx9pzhj 368 33 , , , cord-005646-xhx9pzhj 368 34 ARDS ARDS NNP cord-005646-xhx9pzhj 368 35 was be VBD cord-005646-xhx9pzhj 368 36 defined define VBN cord-005646-xhx9pzhj 368 37 clinically clinically RB cord-005646-xhx9pzhj 368 38 using use VBG cord-005646-xhx9pzhj 368 39 the the DT cord-005646-xhx9pzhj 368 40 criteria criterion NNS cord-005646-xhx9pzhj 368 41 which which WDT cord-005646-xhx9pzhj 368 42 were be VBD cord-005646-xhx9pzhj 368 43 recently recently RB cord-005646-xhx9pzhj 368 44 proposed propose VBN cord-005646-xhx9pzhj 368 45 by by IN cord-005646-xhx9pzhj 368 46 the the DT cord-005646-xhx9pzhj 368 47 American american JJ cord-005646-xhx9pzhj 368 48 - - HYPH cord-005646-xhx9pzhj 368 49 European European NNP cord-005646-xhx9pzhj 368 50 Consensus Consensus NNP cord-005646-xhx9pzhj 368 51 Conference Conference NNP cord-005646-xhx9pzhj 368 52 on on IN cord-005646-xhx9pzhj 368 53 ARDS~ ARDS~ NNP cord-005646-xhx9pzhj 368 54 : : : cord-005646-xhx9pzhj 368 55 acute acute JJ cord-005646-xhx9pzhj 368 56 disease disease NN cord-005646-xhx9pzhj 368 57 onset onset NN cord-005646-xhx9pzhj 368 58 , , , cord-005646-xhx9pzhj 368 59 PaO2 PaO2 NNS cord-005646-xhx9pzhj 368 60 / / SYM cord-005646-xhx9pzhj 368 61 FiO~ fio~ JJ cord-005646-xhx9pzhj 368 62 ratio ratio NN cord-005646-xhx9pzhj 368 63 _ _ NN cord-005646-xhx9pzhj 369 1 < < XX cord-005646-xhx9pzhj 369 2 200 200 CD cord-005646-xhx9pzhj 369 3 mrn mrn NN cord-005646-xhx9pzhj 369 4 Hg Hg NNP cord-005646-xhx9pzhj 369 5 , , , cord-005646-xhx9pzhj 369 6 bilateral bilateral JJ cord-005646-xhx9pzhj 369 7 infiltrates infiltrate VBZ cord-005646-xhx9pzhj 369 8 on on IN cord-005646-xhx9pzhj 369 9 chest chest NN cord-005646-xhx9pzhj 369 10 radiograph radiograph NN cord-005646-xhx9pzhj 369 11 and and CC cord-005646-xhx9pzhj 369 12 absence absence NN cord-005646-xhx9pzhj 369 13 of of IN cord-005646-xhx9pzhj 369 14 clinical clinical JJ cord-005646-xhx9pzhj 369 15 evidence evidence NN cord-005646-xhx9pzhj 369 16 of of IN cord-005646-xhx9pzhj 369 17 left left JJ cord-005646-xhx9pzhj 369 18 atrial atrial JJ cord-005646-xhx9pzhj 369 19 hypertension hypertension NN cord-005646-xhx9pzhj 369 20 . . . cord-005646-xhx9pzhj 370 1 We -PRON- PRP cord-005646-xhx9pzhj 370 2 calculated calculate VBD cord-005646-xhx9pzhj 370 3 the the DT cord-005646-xhx9pzhj 370 4 Murray Murray NNP cord-005646-xhx9pzhj 370 5 lung lung NN cord-005646-xhx9pzhj 370 6 injury injury NN cord-005646-xhx9pzhj 370 7 scores score NNS cord-005646-xhx9pzhj 370 8 modified modify VBN cord-005646-xhx9pzhj 370 9 for for IN cord-005646-xhx9pzhj 370 10 use use NN cord-005646-xhx9pzhj 370 11 in in IN cord-005646-xhx9pzhj 370 12 pediatric pediatric JJ cord-005646-xhx9pzhj 370 13 patients patient NNS cord-005646-xhx9pzhj 370 14 3 3 CD cord-005646-xhx9pzhj 370 15 from from IN cord-005646-xhx9pzhj 370 16 total total JJ cord-005646-xhx9pzhj 370 17 respiratory respiratory JJ cord-005646-xhx9pzhj 370 18 system system NN cord-005646-xhx9pzhj 370 19 compliance compliance NN cord-005646-xhx9pzhj 370 20 , , , cord-005646-xhx9pzhj 370 21 radiographic radiographic JJ cord-005646-xhx9pzhj 370 22 findings finding NNS cord-005646-xhx9pzhj 370 23 , , , cord-005646-xhx9pzhj 370 24 ventilator ventilator NN cord-005646-xhx9pzhj 370 25 settings setting NNS cord-005646-xhx9pzhj 370 26 and and CC cord-005646-xhx9pzhj 370 27 blood blood NN cord-005646-xhx9pzhj 370 28 gas gas NN cord-005646-xhx9pzhj 370 29 results result NNS cord-005646-xhx9pzhj 370 30 . . . cord-005646-xhx9pzhj 371 1 We -PRON- PRP cord-005646-xhx9pzhj 371 2 identified identify VBD cord-005646-xhx9pzhj 371 3 10 10 CD cord-005646-xhx9pzhj 371 4 infants infant NNS cord-005646-xhx9pzhj 371 5 with with IN cord-005646-xhx9pzhj 371 6 severe severe JJ cord-005646-xhx9pzhj 371 7 restrictive restrictive JJ cord-005646-xhx9pzhj 371 8 lung lung NN cord-005646-xhx9pzhj 371 9 disease disease NN cord-005646-xhx9pzhj 371 10 that that WDT cord-005646-xhx9pzhj 371 11 fialfilled fialfille VBD cord-005646-xhx9pzhj 371 12 the the DT cord-005646-xhx9pzhj 371 13 clinical clinical JJ cord-005646-xhx9pzhj 371 14 criteria criterion NNS cord-005646-xhx9pzhj 371 15 fbr fbr NNP cord-005646-xhx9pzhj 371 16 classification classification NN cord-005646-xhx9pzhj 371 17 as as IN cord-005646-xhx9pzhj 371 18 ARDS ARDS NNP cord-005646-xhx9pzhj 371 19 . . . cord-005646-xhx9pzhj 372 1 All all DT cord-005646-xhx9pzhj 372 2 had have VBD cord-005646-xhx9pzhj 372 3 lung lung NN cord-005646-xhx9pzhj 372 4 injury injury NN cord-005646-xhx9pzhj 372 5 scores score NNS cord-005646-xhx9pzhj 372 6 above above IN cord-005646-xhx9pzhj 372 7 2.5 2.5 CD cord-005646-xhx9pzhj 372 8 which which WDT cord-005646-xhx9pzhj 372 9 is be VBZ cord-005646-xhx9pzhj 372 10 the the DT cord-005646-xhx9pzhj 372 11 recommended recommend VBN cord-005646-xhx9pzhj 372 12 cut cut NN cord-005646-xhx9pzhj 372 13 - - HYPH cord-005646-xhx9pzhj 372 14 off off NN cord-005646-xhx9pzhj 372 15 for for IN cord-005646-xhx9pzhj 372 16 a a DT cord-005646-xhx9pzhj 372 17 diagnosis diagnosis NN cord-005646-xhx9pzhj 372 18 of of IN cord-005646-xhx9pzhj 372 19 ARDS ARDS NNP cord-005646-xhx9pzhj 372 20 , , , cord-005646-xhx9pzhj 372 21 Twenty twenty CD cord-005646-xhx9pzhj 372 22 - - HYPH cord-005646-xhx9pzhj 372 23 seven seven CD cord-005646-xhx9pzhj 372 24 infants infant NNS cord-005646-xhx9pzhj 372 25 had have VBD cord-005646-xhx9pzhj 372 26 obstructive obstructive JJ cord-005646-xhx9pzhj 372 27 disease disease NN cord-005646-xhx9pzhj 372 28 consistent consistent JJ cord-005646-xhx9pzhj 372 29 with with IN cord-005646-xhx9pzhj 372 30 a a DT cord-005646-xhx9pzhj 372 31 clinical clinical JJ cord-005646-xhx9pzhj 372 32 diagnosis diagnosis NN cord-005646-xhx9pzhj 372 33 of of IN cord-005646-xhx9pzhj 372 34 bronchiolitis bronchiolitis NN cord-005646-xhx9pzhj 372 35 . . . cord-005646-xhx9pzhj 373 1 The the DT cord-005646-xhx9pzhj 373 2 ARDS ARDS NNP cord-005646-xhx9pzhj 373 3 patients patient NNS cord-005646-xhx9pzhj 373 4 were be VBD cord-005646-xhx9pzhj 373 5 significantly significantly RB cord-005646-xhx9pzhj 373 6 younger young JJR cord-005646-xhx9pzhj 373 7 , , , cord-005646-xhx9pzhj 373 8 had have VBD cord-005646-xhx9pzhj 373 9 a a DT cord-005646-xhx9pzhj 373 10 longer long JJR cord-005646-xhx9pzhj 373 11 time time NN cord-005646-xhx9pzhj 373 12 of of IN cord-005646-xhx9pzhj 373 13 assisted assist VBN cord-005646-xhx9pzhj 373 14 ventilation ventilation NN cord-005646-xhx9pzhj 374 1 ( ( -LRB- cord-005646-xhx9pzhj 374 2 p p NN cord-005646-xhx9pzhj 374 3 < < XX cord-005646-xhx9pzhj 374 4 0.05 0.05 CD cord-005646-xhx9pzhj 374 5 ) ) -RRB- cord-005646-xhx9pzhj 374 6 and and CC cord-005646-xhx9pzhj 374 7 a a DT cord-005646-xhx9pzhj 374 8 greater great JJR cord-005646-xhx9pzhj 374 9 proportion proportion NN cord-005646-xhx9pzhj 374 10 of of IN cord-005646-xhx9pzhj 374 11 infants infant NNS cord-005646-xhx9pzhj 374 12 with with IN cord-005646-xhx9pzhj 374 13 preexisting preexist VBG cord-005646-xhx9pzhj 374 14 illnesses illness NNS cord-005646-xhx9pzhj 374 15 ( ( -LRB- cord-005646-xhx9pzhj 374 16 p=0.023 p=0.023 NNS cord-005646-xhx9pzhj 374 17 , , , cord-005646-xhx9pzhj 374 18 Odds Odds NNPS cord-005646-xhx9pzhj 374 19 ratio ratio NN cord-005646-xhx9pzhj 374 20 = = SYM cord-005646-xhx9pzhj 374 21 6.67 6.67 CD cord-005646-xhx9pzhj 374 22 ) ) -RRB- cord-005646-xhx9pzhj 375 1 when when WRB cord-005646-xhx9pzhj 375 2 compared compare VBN cord-005646-xhx9pzhj 375 3 to to IN cord-005646-xhx9pzhj 375 4 the the DT cord-005646-xhx9pzhj 375 5 patients patient NNS cord-005646-xhx9pzhj 375 6 with with IN cord-005646-xhx9pzhj 375 7 obstructive obstructive JJ cord-005646-xhx9pzhj 375 8 disease disease NN cord-005646-xhx9pzhj 375 9 . . . cord-005646-xhx9pzhj 376 1 With with IN cord-005646-xhx9pzhj 376 2 the the DT cord-005646-xhx9pzhj 376 3 exception exception NN cord-005646-xhx9pzhj 376 4 of of IN cord-005646-xhx9pzhj 376 5 one one CD cord-005646-xhx9pzhj 376 6 immunodeficient immunodeficient JJ cord-005646-xhx9pzhj 376 7 patient patient NN cord-005646-xhx9pzhj 376 8 , , , cord-005646-xhx9pzhj 376 9 none none NN cord-005646-xhx9pzhj 376 10 of of IN cord-005646-xhx9pzhj 376 11 these these DT cord-005646-xhx9pzhj 376 12 infants infant NNS cord-005646-xhx9pzhj 376 13 died die VBD cord-005646-xhx9pzhj 376 14 . . . cord-005646-xhx9pzhj 377 1 Given give VBN cord-005646-xhx9pzhj 377 2 the the DT cord-005646-xhx9pzhj 377 3 low low JJ cord-005646-xhx9pzhj 377 4 mortality mortality NN cord-005646-xhx9pzhj 377 5 despite despite IN cord-005646-xhx9pzhj 377 6 a a DT cord-005646-xhx9pzhj 377 7 clinical clinical JJ cord-005646-xhx9pzhj 377 8 picture picture NN cord-005646-xhx9pzhj 377 9 of of IN cord-005646-xhx9pzhj 377 10 severe severe JJ cord-005646-xhx9pzhj 377 11 lung lung NN cord-005646-xhx9pzhj 377 12 injury injury NN cord-005646-xhx9pzhj 377 13 , , , cord-005646-xhx9pzhj 377 14 there there EX cord-005646-xhx9pzhj 377 15 is be VBZ cord-005646-xhx9pzhj 377 16 evidence evidence NN cord-005646-xhx9pzhj 377 17 that that IN cord-005646-xhx9pzhj 377 18 RSV RSV NNP cord-005646-xhx9pzhj 377 19 induced induce VBD cord-005646-xhx9pzhj 377 20 respiratory respiratory JJ cord-005646-xhx9pzhj 377 21 failure failure NN cord-005646-xhx9pzhj 377 22 may may MD cord-005646-xhx9pzhj 377 23 represent represent VB cord-005646-xhx9pzhj 377 24 a a DT cord-005646-xhx9pzhj 377 25 relatively relatively RB cord-005646-xhx9pzhj 377 26 benign benign JJ cord-005646-xhx9pzhj 377 27 cause cause NN cord-005646-xhx9pzhj 377 28 of of IN cord-005646-xhx9pzhj 377 29 ARDS ARDS NNP cord-005646-xhx9pzhj 377 30 in in IN cord-005646-xhx9pzhj 377 31 pediatric pediatric JJ cord-005646-xhx9pzhj 377 32 patients patient NNS cord-005646-xhx9pzhj 377 33 , , , cord-005646-xhx9pzhj 377 34 Bachmann Bachmann NNP cord-005646-xhx9pzhj 377 35 An an DT cord-005646-xhx9pzhj 377 36 audit audit NN cord-005646-xhx9pzhj 377 37 of of IN cord-005646-xhx9pzhj 377 38 patients patient NNS cord-005646-xhx9pzhj 377 39 with with IN cord-005646-xhx9pzhj 377 40 severe severe JJ cord-005646-xhx9pzhj 377 41 acute acute JJ cord-005646-xhx9pzhj 377 42 bypoxic bypoxic JJ cord-005646-xhx9pzhj 377 43 respiratory respiratory JJ cord-005646-xhx9pzhj 377 44 failure failure NN cord-005646-xhx9pzhj 377 45 ( ( -LRB- cord-005646-xhx9pzhj 377 46 AHRF AHRF NNP cord-005646-xhx9pzhj 377 47 ) ) -RRB- cord-005646-xhx9pzhj 377 48 receiving receive VBG cord-005646-xhx9pzhj 377 49 highfrequency highfrequency NNP cord-005646-xhx9pzhj 377 50 oscillatory oscillatory JJ cord-005646-xhx9pzhj 377 51 ventilation ventilation NN cord-005646-xhx9pzhj 377 52 ( ( -LRB- cord-005646-xhx9pzhj 377 53 HFOV HFOV NNP cord-005646-xhx9pzhj 377 54 ) ) -RRB- cord-005646-xhx9pzhj 377 55 in in IN cord-005646-xhx9pzhj 377 56 our -PRON- PRP$ cord-005646-xhx9pzhj 377 57 unit unit NN cord-005646-xhx9pzhj 377 58 ( ( -LRB- cord-005646-xhx9pzhj 377 59 n=32 n=32 RB cord-005646-xhx9pzhj 377 60 , , , cord-005646-xhx9pzhj 377 61 mortality mortality NN cord-005646-xhx9pzhj 377 62 75 75 CD cord-005646-xhx9pzhj 377 63 % % NN cord-005646-xhx9pzhj 377 64 ) ) -RRB- cord-005646-xhx9pzhj 377 65 revealed reveal VBD cord-005646-xhx9pzhj 377 66 that that IN cord-005646-xhx9pzhj 377 67 sub sub NN cord-005646-xhx9pzhj 377 68 - - NNS cord-005646-xhx9pzhj 377 69 groups group NNS cord-005646-xhx9pzhj 377 70 with with IN cord-005646-xhx9pzhj 377 71 severe severe JJ cord-005646-xhx9pzhj 377 72 underlying underlie VBG cord-005646-xhx9pzhj 377 73 disease disease NN cord-005646-xhx9pzhj 377 74 ( ( -LRB- cord-005646-xhx9pzhj 377 75 n=14 n=14 RB cord-005646-xhx9pzhj 377 76 , , , cord-005646-xhx9pzhj 377 77 mortality mortality NN cord-005646-xhx9pzhj 377 78 100%)and 100%)and CD cord-005646-xhx9pzhj 378 1 those those DT cord-005646-xhx9pzhj 378 2 with with IN cord-005646-xhx9pzhj 378 3 mu mu NNP cord-005646-xhx9pzhj 378 4 ~ ~ NNP cord-005646-xhx9pzhj 378 5 pie pie NN cord-005646-xhx9pzhj 378 6 organ organ NN cord-005646-xhx9pzhj 378 7 failure failure NN cord-005646-xhx9pzhj 378 8 ( ( -LRB- cord-005646-xhx9pzhj 378 9 > > NFP cord-005646-xhx9pzhj 378 10 2 2 CD cord-005646-xhx9pzhj 378 11 systems system NNS cord-005646-xhx9pzhj 378 12 failing fail VBG cord-005646-xhx9pzhj 378 13 , , , cord-005646-xhx9pzhj 378 14 n=7 n=7 JJ cord-005646-xhx9pzhj 378 15 mortality mortality NN cord-005646-xhx9pzhj 378 16 100 100 CD cord-005646-xhx9pzhj 378 17 % % NN cord-005646-xhx9pzhj 378 18 ) ) -RRB- cord-005646-xhx9pzhj 378 19 accounted account VBD cord-005646-xhx9pzhj 378 20 for for IN cord-005646-xhx9pzhj 378 21 all all PDT cord-005646-xhx9pzhj 378 22 the the DT cord-005646-xhx9pzhj 378 23 deaths death NNS cord-005646-xhx9pzhj 378 24 beyond beyond IN cord-005646-xhx9pzhj 378 25 the the DT cord-005646-xhx9pzhj 378 26 neonatal neonatal JJ cord-005646-xhx9pzhj 378 27 period period NN cord-005646-xhx9pzhj 378 28 . . . cord-005646-xhx9pzhj 379 1 V~ V~ NNP cord-005646-xhx9pzhj 379 2 therefore therefore RB cord-005646-xhx9pzhj 379 3 hypothesized hypothesize VBD cord-005646-xhx9pzhj 379 4 that that IN cord-005646-xhx9pzhj 379 5 in in IN cord-005646-xhx9pzhj 379 6 a a DT cord-005646-xhx9pzhj 379 7 modem modem NN cord-005646-xhx9pzhj 379 8 paedistric paedistric JJ cord-005646-xhx9pzhj 379 9 intensive intensive JJ cord-005646-xhx9pzhj 379 10 care care NN cord-005646-xhx9pzhj 379 11 unit unit NN cord-005646-xhx9pzhj 379 12 ( ( -LRB- cord-005646-xhx9pzhj 379 13 PICU PICU NNP cord-005646-xhx9pzhj 379 14 ) ) -RRB- cord-005646-xhx9pzhj 379 15 : : : cord-005646-xhx9pzhj 379 16 a a LS cord-005646-xhx9pzhj 379 17 ) ) -RRB- cord-005646-xhx9pzhj 379 18 children child NNS cord-005646-xhx9pzhj 379 19 greater great JJR cord-005646-xhx9pzhj 379 20 than than IN cord-005646-xhx9pzhj 379 21 one one CD cord-005646-xhx9pzhj 379 22 month month NN cord-005646-xhx9pzhj 379 23 of of IN cord-005646-xhx9pzhj 379 24 age age NN cord-005646-xhx9pzhj 379 25 with with IN cord-005646-xhx9pzhj 379 26 AHRF AHRF NNP cord-005646-xhx9pzhj 379 27 do do VBP cord-005646-xhx9pzhj 379 28 not not RB cord-005646-xhx9pzhj 379 29 die die VB cord-005646-xhx9pzhj 379 30 in in IN cord-005646-xhx9pzhj 379 31 the the DT cord-005646-xhx9pzhj 379 32 absence absence NN cord-005646-xhx9pzhj 379 33 of of IN cord-005646-xhx9pzhj 379 34 severe severe JJ cord-005646-xhx9pzhj 379 35 , , , cord-005646-xhx9pzhj 379 36 pre pre JJ cord-005646-xhx9pzhj 379 37 - - JJ cord-005646-xhx9pzhj 379 38 existing existing JJ cord-005646-xhx9pzhj 379 39 disease disease NN cord-005646-xhx9pzhj 379 40 or or CC cord-005646-xhx9pzhj 379 41 multi multi JJ cord-005646-xhx9pzhj 379 42 - - JJ cord-005646-xhx9pzhj 379 43 organ organ JJ cord-005646-xhx9pzhj 379 44 dysfunction dysfunction NN cord-005646-xhx9pzhj 379 45 syndrome syndrome NN cord-005646-xhx9pzhj 379 46 , , , cord-005646-xhx9pzhj 379 47 b b LS cord-005646-xhx9pzhj 379 48 ) ) -RRB- cord-005646-xhx9pzhj 379 49 respiratory respiratory JJ cord-005646-xhx9pzhj 379 50 parameters parameter NNS cord-005646-xhx9pzhj 379 51 alone alone RB cord-005646-xhx9pzhj 379 52 will will MD cord-005646-xhx9pzhj 379 53 predict predict VB cord-005646-xhx9pzhj 379 54 outcome outcome NN cord-005646-xhx9pzhj 379 55 poorly poorly RB cord-005646-xhx9pzhj 379 56 in in IN cord-005646-xhx9pzhj 379 57 AHRF AHRF NNP cord-005646-xhx9pzhj 379 58 . . . cord-005646-xhx9pzhj 380 1 Method Method NNP cord-005646-xhx9pzhj 380 2 Prospect~/e Prospect~/e NNP cord-005646-xhx9pzhj 380 3 sty sty NNP cord-005646-xhx9pzhj 380 4 / / SYM cord-005646-xhx9pzhj 380 5 of of IN cord-005646-xhx9pzhj 380 6 all all DT cord-005646-xhx9pzhj 380 7 adm adm NNP cord-005646-xhx9pzhj 381 1 ~ns ~ns JJ cord-005646-xhx9pzhj 381 2 to to IN cord-005646-xhx9pzhj 381 3 our -PRON- PRP$ cord-005646-xhx9pzhj 381 4 tertiary tertiary JJ cord-005646-xhx9pzhj 381 5 PICU PICU NNP cord-005646-xhx9pzhj 381 6 . . . cord-005646-xhx9pzhj 382 1 Data datum NNS cord-005646-xhx9pzhj 382 2 it -PRON- PRP cord-005646-xhx9pzhj 382 3 , , , cord-005646-xhx9pzhj 382 4 citing cite VBG cord-005646-xhx9pzhj 382 5 the the DT cord-005646-xhx9pzhj 382 6 respiratory respiratory JJ cord-005646-xhx9pzhj 382 7 parameters parameter NNS cord-005646-xhx9pzhj 382 8 ( ( -LRB- cord-005646-xhx9pzhj 382 9 oxygena oxygena NNP cord-005646-xhx9pzhj 382 10 ~ ~ NFP cord-005646-xhx9pzhj 382 11 n n CC cord-005646-xhx9pzhj 382 12 index index NN cord-005646-xhx9pzhj 382 13 [ [ -LRB- cord-005646-xhx9pzhj 382 14 Ol old NNP cord-005646-xhx9pzhj 382 15 ] ] -RRB- cord-005646-xhx9pzhj 382 16 , , , cord-005646-xhx9pzhj 382 17 aiveolar aiveolar RB cord-005646-xhx9pzhj 382 18 - - HYPH cord-005646-xhx9pzhj 382 19 artedal artedal RB cord-005646-xhx9pzhj 382 20 oxygen oxygen NN cord-005646-xhx9pzhj 382 21 tension tension NN cord-005646-xhx9pzhj 382 22 gradient gradient NN cord-005646-xhx9pzhj 382 23 , , , cord-005646-xhx9pzhj 382 24 PaO2 PaO2 NNS cord-005646-xhx9pzhj 382 25 / / SYM cord-005646-xhx9pzhj 382 26 FiO2 FiO2 NNP cord-005646-xhx9pzhj 382 27 ratio ratio NN cord-005646-xhx9pzhj 382 28 ) ) -RRB- cord-005646-xhx9pzhj 382 29 were be VBD cord-005646-xhx9pzhj 382 30 collected collect VBN cord-005646-xhx9pzhj 382 31 hourly hourly RB cord-005646-xhx9pzhj 382 32 from from IN cord-005646-xhx9pzhj 382 33 the the DT cord-005646-xhx9pzhj 382 34 bedside bedside NN cord-005646-xhx9pzhj 382 35 charts chart NNS cord-005646-xhx9pzhj 382 36 throughout throughout IN cord-005646-xhx9pzhj 382 37 admission admission NN cord-005646-xhx9pzhj 382 38 . . . cord-005646-xhx9pzhj 383 1 Patients patient NNS cord-005646-xhx9pzhj 383 2 were be VBD cord-005646-xhx9pzhj 383 3 included include VBN cord-005646-xhx9pzhj 383 4 in in IN cord-005646-xhx9pzhj 383 5 the the DT cord-005646-xhx9pzhj 383 6 study study NN cord-005646-xhx9pzhj 383 7 if if IN cord-005646-xhx9pzhj 383 8 AHRF AHRF NNP cord-005646-xhx9pzhj 383 9 was be VBD cord-005646-xhx9pzhj 383 10 present present JJ cord-005646-xhx9pzhj 383 11 at at IN cord-005646-xhx9pzhj 383 12 admission admission NN cord-005646-xhx9pzhj 384 1 either either CC cord-005646-xhx9pzhj 384 2 None none NN cord-005646-xhx9pzhj 384 3 or or CC cord-005646-xhx9pzhj 384 4 in in IN cord-005646-xhx9pzhj 384 5 combination combination NN cord-005646-xhx9pzhj 384 6 with with IN cord-005646-xhx9pzhj 384 7 other other JJ cord-005646-xhx9pzhj 384 8 organ organ NN cord-005646-xhx9pzhj 384 9 dysfun dysfun NN cord-005646-xhx9pzhj 384 10 ~ ~ NFP cord-005646-xhx9pzhj 384 11 on on IN cord-005646-xhx9pzhj 384 12 . . . cord-005646-xhx9pzhj 385 1 AHRF AHRF NNP cord-005646-xhx9pzhj 385 2 was be VBD cord-005646-xhx9pzhj 385 3 defined define VBN cord-005646-xhx9pzhj 385 4 as as IN cord-005646-xhx9pzhj 385 5 the the DT cord-005646-xhx9pzhj 385 6 acute acute NN cord-005646-xhx9pzhj 385 7 ( ( -LRB- cord-005646-xhx9pzhj 385 8 < < XX cord-005646-xhx9pzhj 385 9 48hour 48hour NNP cord-005646-xhx9pzhj 385 10 ) ) -RRB- cord-005646-xhx9pzhj 385 11 onset onset NN cord-005646-xhx9pzhj 385 12 of of IN cord-005646-xhx9pzhj 385 13 respiratory respiratory JJ cord-005646-xhx9pzhj 385 14 dysfunctk:~l dysfunctk:~l NNS cord-005646-xhx9pzhj 385 15 with with IN cord-005646-xhx9pzhj 385 16 a a DT cord-005646-xhx9pzhj 385 17 PaO2 PaO2 NNS cord-005646-xhx9pzhj 385 18 / / SYM cord-005646-xhx9pzhj 385 19 FiO2 FiO2 NNS cord-005646-xhx9pzhj 385 20 ratio ratio NN cord-005646-xhx9pzhj 385 21 . . . cord-005646-xhx9pzhj 386 1 < < XX cord-005646-xhx9pzhj 386 2 200 200 CD cord-005646-xhx9pzhj 386 3 for for IN cord-005646-xhx9pzhj 386 4 six six CD cord-005646-xhx9pzhj 386 5 consecutive consecutive JJ cord-005646-xhx9pzhj 386 6 hours hour NNS cord-005646-xhx9pzhj 386 7 dunng dunng RB cord-005646-xhx9pzhj 386 8 the the DT cord-005646-xhx9pzhj 386 9 first first JJ cord-005646-xhx9pzhj 386 10 24 24 CD cord-005646-xhx9pzhj 386 11 hours hour NNS cord-005646-xhx9pzhj 386 12 of of IN cord-005646-xhx9pzhj 386 13 admission admission NN cord-005646-xhx9pzhj 386 14 ( ( -LRB- cord-005646-xhx9pzhj 386 15 with with IN cord-005646-xhx9pzhj 386 16 no no DT cord-005646-xhx9pzhj 386 17 evidence evidence NN cord-005646-xhx9pzhj 386 18 of of IN cord-005646-xhx9pzhj 386 19 left left JJ cord-005646-xhx9pzhj 386 20 anal anal JJ cord-005646-xhx9pzhj 386 21 hypertension hypertension NN cord-005646-xhx9pzhj 386 22 ) ) -RRB- cord-005646-xhx9pzhj 386 23 , , , cord-005646-xhx9pzhj 386 24 X x NN cord-005646-xhx9pzhj 386 25 - - NN cord-005646-xhx9pzhj 386 26 ray ray JJ cord-005646-xhx9pzhj 386 27 review review NN cord-005646-xhx9pzhj 386 28 defined define VBD cord-005646-xhx9pzhj 386 29 a a DT cord-005646-xhx9pzhj 386 30 sub sub NN cord-005646-xhx9pzhj 386 31 - - JJ cord-005646-xhx9pzhj 386 32 group group NN cord-005646-xhx9pzhj 386 33 of of IN cord-005646-xhx9pzhj 386 34 patients patient NNS cord-005646-xhx9pzhj 386 35 with with IN cord-005646-xhx9pzhj 386 36 Acute acute JJ cord-005646-xhx9pzhj 386 37 Respiratory respiratory JJ cord-005646-xhx9pzhj 386 38 Distress Distress NNP cord-005646-xhx9pzhj 386 39 Syndrome Syndrome NNP cord-005646-xhx9pzhj 386 40 ( ( -LRB- cord-005646-xhx9pzhj 386 41 ARDS ARDS NNP cord-005646-xhx9pzhj 386 42 ) ) -RRB- cord-005646-xhx9pzhj 386 43 by by IN cord-005646-xhx9pzhj 386 44 the the DT cord-005646-xhx9pzhj 386 45 presence presence NN cord-005646-xhx9pzhj 386 46 of of IN cord-005646-xhx9pzhj 386 47 bilateral bilateral JJ cord-005646-xhx9pzhj 386 48 interstitial interstitial JJ cord-005646-xhx9pzhj 386 49 infiltrates infiltrate NNS cord-005646-xhx9pzhj 386 50 . . . cord-005646-xhx9pzhj 387 1 Results result NNS cord-005646-xhx9pzhj 388 1 To to IN cord-005646-xhx9pzhj 388 2 date date NN cord-005646-xhx9pzhj 388 3 59 59 CD cord-005646-xhx9pzhj 388 4 children child NNS cord-005646-xhx9pzhj 388 5 ( ( -LRB- cord-005646-xhx9pzhj 388 6 ages age NNS cord-005646-xhx9pzhj 388 7 1 1 CD cord-005646-xhx9pzhj 388 8 - - SYM cord-005646-xhx9pzhj 388 9 168 168 CD cord-005646-xhx9pzhj 388 10 months month NNS cord-005646-xhx9pzhj 388 11 , , , cord-005646-xhx9pzhj 388 12 weight weight NN cord-005646-xhx9pzhj 388 13 1.2 1.2 CD cord-005646-xhx9pzhj 388 14 - - SYM cord-005646-xhx9pzhj 388 15 70 70 CD cord-005646-xhx9pzhj 388 16 kg kg NNS cord-005646-xhx9pzhj 388 17 ) ) -RRB- cord-005646-xhx9pzhj 388 18 have have VBP cord-005646-xhx9pzhj 388 19 been be VBN cord-005646-xhx9pzhj 388 20 admitted admit VBN cord-005646-xhx9pzhj 388 21 in in IN cord-005646-xhx9pzhj 388 22 AHRF AHRF NNP cord-005646-xhx9pzhj 388 23 . . . cord-005646-xhx9pzhj 389 1 18 18 CD cord-005646-xhx9pzhj 389 2 of of IN cord-005646-xhx9pzhj 389 3 these these DT cord-005646-xhx9pzhj 389 4 also also RB cord-005646-xhx9pzhj 389 5 had have VBD cord-005646-xhx9pzhj 389 6 ARDS ARDS NNP cord-005646-xhx9pzhj 389 7 . . . cord-005646-xhx9pzhj 390 1 The the DT cord-005646-xhx9pzhj 390 2 overall overall JJ cord-005646-xhx9pzhj 390 3 mortality mortality NN cord-005646-xhx9pzhj 390 4 was be VBD cord-005646-xhx9pzhj 390 5 23.7 23.7 CD cord-005646-xhx9pzhj 390 6 % % NN cord-005646-xhx9pzhj 390 7 ( ( -LRB- cord-005646-xhx9pzhj 390 8 14/59 14/59 CD cord-005646-xhx9pzhj 390 9 ) ) -RRB- cord-005646-xhx9pzhj 390 10 , , , cord-005646-xhx9pzhj 390 11 and and CC cord-005646-xhx9pzhj 390 12 greater great JJR cord-005646-xhx9pzhj 390 13 in in IN cord-005646-xhx9pzhj 390 14 the the DT cord-005646-xhx9pzhj 390 15 ARDS ARDS NNP cord-005646-xhx9pzhj 390 16 group group NN cord-005646-xhx9pzhj 390 17 than than IN cord-005646-xhx9pzhj 390 18 the the DT cord-005646-xhx9pzhj 390 19 non non NNP cord-005646-xhx9pzhj 390 20 - - JJ cord-005646-xhx9pzhj 390 21 ARDS ARDS NNP cord-005646-xhx9pzhj 390 22 group group NN cord-005646-xhx9pzhj 390 23 ( ( -LRB- cord-005646-xhx9pzhj 390 24 10t18 10t18 CD cord-005646-xhx9pzhj 390 25 , , , cord-005646-xhx9pzhj 390 26 55.5 55.5 CD cord-005646-xhx9pzhj 390 27 % % NN cord-005646-xhx9pzhj 390 28 Vs Vs NNP cord-005646-xhx9pzhj 390 29 , , , cord-005646-xhx9pzhj 390 30 4141 4141 CD cord-005646-xhx9pzhj 390 31 , , , cord-005646-xhx9pzhj 390 32 9.7 9.7 CD cord-005646-xhx9pzhj 390 33 % % NN cord-005646-xhx9pzhj 390 34 , , , cord-005646-xhx9pzhj 390 35 p p NN cord-005646-xhx9pzhj 390 36 < < XX cord-005646-xhx9pzhj 390 37 O.01 o.01 CD cord-005646-xhx9pzhj 390 38 ) ) -RRB- cord-005646-xhx9pzhj 390 39 . . . cord-005646-xhx9pzhj 391 1 It -PRON- PRP cord-005646-xhx9pzhj 391 2 was be VBD cord-005646-xhx9pzhj 391 3 not not RB cord-005646-xhx9pzhj 391 4 possible possible JJ cord-005646-xhx9pzhj 391 5 to to TO cord-005646-xhx9pzhj 391 6 predict predict VB cord-005646-xhx9pzhj 391 7 survivors survivor NNS cord-005646-xhx9pzhj 391 8 from from IN cord-005646-xhx9pzhj 391 9 non non NNS cord-005646-xhx9pzhj 391 10 - - NNS cord-005646-xhx9pzhj 391 11 survivors survivor NNS cord-005646-xhx9pzhj 391 12 on on IN cord-005646-xhx9pzhj 391 13 the the DT cord-005646-xhx9pzhj 391 14 basis basis NN cord-005646-xhx9pzhj 391 15 of of IN cord-005646-xhx9pzhj 391 16 the the DT cord-005646-xhx9pzhj 391 17 seventy seventy CD cord-005646-xhx9pzhj 391 18 of of IN cord-005646-xhx9pzhj 391 19 the the DT cord-005646-xhx9pzhj 391 20 respiratory respiratory JJ cord-005646-xhx9pzhj 391 21 failure failure NN cord-005646-xhx9pzhj 391 22 alone alone RB cord-005646-xhx9pzhj 391 23 , , , cord-005646-xhx9pzhj 392 1 The the DT cord-005646-xhx9pzhj 392 2 A A NNP cord-005646-xhx9pzhj 392 3 - - HYPH cord-005646-xhx9pzhj 392 4 aDO2 ado2 NN cord-005646-xhx9pzhj 392 5 on on IN cord-005646-xhx9pzhj 392 6 the the DT cord-005646-xhx9pzhj 392 7 day day NN cord-005646-xhx9pzhj 392 8 of of IN cord-005646-xhx9pzhj 392 9 admission admission NN cord-005646-xhx9pzhj 392 10 ( ( -LRB- cord-005646-xhx9pzhj 392 11 best good JJS cord-005646-xhx9pzhj 392 12 in in IN cord-005646-xhx9pzhj 392 13 24 24 CD cord-005646-xhx9pzhj 392 14 hours hour NNS cord-005646-xhx9pzhj 392 15 ) ) -RRB- cord-005646-xhx9pzhj 392 16 was be VBD cord-005646-xhx9pzhj 392 17 not not RB cord-005646-xhx9pzhj 392 18 significantly significantly RB cord-005646-xhx9pzhj 392 19 different different JJ cord-005646-xhx9pzhj 392 20 between between IN cord-005646-xhx9pzhj 392 21 survivors survivor NNS cord-005646-xhx9pzhj 392 22 and and CC cord-005646-xhx9pzhj 392 23 non non NNS cord-005646-xhx9pzhj 392 24 - - NNS cord-005646-xhx9pzhj 392 25 survivors survivor NNS cord-005646-xhx9pzhj 392 26 : : : cord-005646-xhx9pzhj 393 1 ( ( -LRB- cord-005646-xhx9pzhj 393 2 mean mean UH cord-005646-xhx9pzhj 393 3 , , , cord-005646-xhx9pzhj 393 4 + + CC cord-005646-xhx9pzhj 393 5 sd)(174 sd)(174 JJ cord-005646-xhx9pzhj 394 1 mmHg mmHg NNP cord-005646-xhx9pzhj 394 2 + + CC cord-005646-xhx9pzhj 394 3 _ _ NN cord-005646-xhx9pzhj 394 4 108 108 CD cord-005646-xhx9pzhj 394 5 , , , cord-005646-xhx9pzhj 394 6 Vs Vs NNP cord-005646-xhx9pzhj 394 7 304 304 CD cord-005646-xhx9pzhj 394 8 mmHg mmhg NN cord-005646-xhx9pzhj 394 9 _ _ NN cord-005646-xhx9pzhj 394 10 + + CC cord-005646-xhx9pzhj 394 11 _ _ NN cord-005646-xhx9pzhj 394 12 156 156 CD cord-005646-xhx9pzhj 394 13 ) ) -RRB- cord-005646-xhx9pzhj 394 14 . . . cord-005646-xhx9pzhj 395 1 kdl kdl NNP cord-005646-xhx9pzhj 395 2 non non NNP cord-005646-xhx9pzhj 395 3 - - NNS cord-005646-xhx9pzhj 395 4 survivors survivor NNS cord-005646-xhx9pzhj 395 5 were be VBD cord-005646-xhx9pzhj 395 6 immunodeficient immunodeficient JJ cord-005646-xhx9pzhj 395 7 ( ( -LRB- cord-005646-xhx9pzhj 395 8 n=8 n=8 NN cord-005646-xhx9pzhj 395 9 ) ) -RRB- cord-005646-xhx9pzhj 395 10 , , , cord-005646-xhx9pzhj 395 11 previously previously RB cord-005646-xhx9pzhj 395 12 extmrnsly extmrnsly RB cord-005646-xhx9pzhj 395 13 premature premature JJ cord-005646-xhx9pzhj 395 14 infants infant NNS cord-005646-xhx9pzhj 395 15 ( ( -LRB- cord-005646-xhx9pzhj 395 16 < < NNP cord-005646-xhx9pzhj 395 17 28140),(n=3 28140),(n=3 CD cord-005646-xhx9pzhj 395 18 ) ) -RRB- cord-005646-xhx9pzhj 395 19 or or CC cord-005646-xhx9pzhj 395 20 suffedng suffedng NN cord-005646-xhx9pzhj 395 21 fcom fcom NN cord-005646-xhx9pzhj 395 22 chronic chronic JJ cord-005646-xhx9pzhj 395 23 metabolic metabolic JJ cord-005646-xhx9pzhj 395 24 or or CC cord-005646-xhx9pzhj 395 25 gastrointestinal gastrointestinal JJ cord-005646-xhx9pzhj 395 26 disease disease NN cord-005646-xhx9pzhj 395 27 ( ( -LRB- cord-005646-xhx9pzhj 395 28 n=3 n=3 NN cord-005646-xhx9pzhj 395 29 ) ) -RRB- cord-005646-xhx9pzhj 395 30 . . . cord-005646-xhx9pzhj 396 1 No no DT cord-005646-xhx9pzhj 396 2 previously previously RB cord-005646-xhx9pzhj 396 3 normal normal JJ cord-005646-xhx9pzhj 396 4 child child NN cord-005646-xhx9pzhj 396 5 died die VBD cord-005646-xhx9pzhj 396 6 . . . cord-005646-xhx9pzhj 397 1 Conclusion conclusion NN cord-005646-xhx9pzhj 398 1 The the DT cord-005646-xhx9pzhj 398 2 severity severity NN cord-005646-xhx9pzhj 398 3 of of IN cord-005646-xhx9pzhj 398 4 respiratory respiratory JJ cord-005646-xhx9pzhj 398 5 failure failure NN cord-005646-xhx9pzhj 398 6 does do VBZ cord-005646-xhx9pzhj 398 7 not not RB cord-005646-xhx9pzhj 398 8 allow allow VB cord-005646-xhx9pzhj 398 9 prediolJon prediolJon NNP cord-005646-xhx9pzhj 398 10 of of IN cord-005646-xhx9pzhj 398 11 outcome outcome NN cord-005646-xhx9pzhj 398 12 in in IN cord-005646-xhx9pzhj 398 13 our -PRON- PRP$ cord-005646-xhx9pzhj 398 14 patients patient NNS cord-005646-xhx9pzhj 398 15 . . . cord-005646-xhx9pzhj 399 1 We -PRON- PRP cord-005646-xhx9pzhj 399 2 believe believe VBP cord-005646-xhx9pzhj 399 3 that that IN cord-005646-xhx9pzhj 399 4 this this DT cord-005646-xhx9pzhj 399 5 reflects reflect VBZ cord-005646-xhx9pzhj 399 6 that that IN cord-005646-xhx9pzhj 399 7 modem modem NN cord-005646-xhx9pzhj 399 8 PICU PICU NNP cord-005646-xhx9pzhj 399 9 is be VBZ cord-005646-xhx9pzhj 399 10 so so RB cord-005646-xhx9pzhj 399 11 effective effective JJ cord-005646-xhx9pzhj 399 12 at at IN cord-005646-xhx9pzhj 399 13 providing provide VBG cord-005646-xhx9pzhj 399 14 respiratory respiratory JJ cord-005646-xhx9pzhj 399 15 support support NN cord-005646-xhx9pzhj 399 16 that that WDT cord-005646-xhx9pzhj 399 17 pre pre JJ cord-005646-xhx9pzhj 399 18 - - JJ cord-005646-xhx9pzhj 399 19 existing existing JJ cord-005646-xhx9pzhj 399 20 pathology pathology NN cord-005646-xhx9pzhj 399 21 alone alone RB cord-005646-xhx9pzhj 399 22 de~ de~ VBZ cord-005646-xhx9pzhj 399 23 prognosis prognosis NN cord-005646-xhx9pzhj 399 24 . . . cord-005646-xhx9pzhj 400 1 This this DT cord-005646-xhx9pzhj 400 2 suggests suggest VBZ cord-005646-xhx9pzhj 400 3 that that IN cord-005646-xhx9pzhj 400 4 an an DT cord-005646-xhx9pzhj 400 5 abnormally abnormally RB cord-005646-xhx9pzhj 400 6 regulated regulate VBN cord-005646-xhx9pzhj 400 7 host host NN cord-005646-xhx9pzhj 400 8 response response NN cord-005646-xhx9pzhj 400 9 or or CC cord-005646-xhx9pzhj 400 10 abnormal abnormal JJ cord-005646-xhx9pzhj 400 11 persistence persistence NN cord-005646-xhx9pzhj 400 12 of of IN cord-005646-xhx9pzhj 400 13 a a DT cord-005646-xhx9pzhj 400 14 pathogen pathogen NN cord-005646-xhx9pzhj 400 15 may may MD cord-005646-xhx9pzhj 400 16 be be VB cord-005646-xhx9pzhj 400 17 required require VBN cord-005646-xhx9pzhj 400 18 to to TO cord-005646-xhx9pzhj 400 19 induce induce VB cord-005646-xhx9pzhj 400 20 lung lung NN cord-005646-xhx9pzhj 400 21 injury injury NN cord-005646-xhx9pzhj 400 22 of of IN cord-005646-xhx9pzhj 400 23 sufficient sufficient JJ cord-005646-xhx9pzhj 400 24 severity severity NN cord-005646-xhx9pzhj 400 25 that that WDT cord-005646-xhx9pzhj 400 26 the the DT cord-005646-xhx9pzhj 400 27 resulting result VBG cord-005646-xhx9pzhj 400 28 respiratory respiratory JJ cord-005646-xhx9pzhj 400 29 failure failure NN cord-005646-xhx9pzhj 400 30 can can MD cord-005646-xhx9pzhj 400 31 not not RB cord-005646-xhx9pzhj 400 32 be be VB cord-005646-xhx9pzhj 400 33 supported support VBN cord-005646-xhx9pzhj 400 34 in in IN cord-005646-xhx9pzhj 400 35 a a DT cord-005646-xhx9pzhj 400 36 modem modem NN cord-005646-xhx9pzhj 400 37 PICU PICU NNP cord-005646-xhx9pzhj 400 38 . . . cord-005646-xhx9pzhj 401 1 Introduction introduction NN cord-005646-xhx9pzhj 401 2 : : : cord-005646-xhx9pzhj 401 3 Postural postural JJ cord-005646-xhx9pzhj 401 4 changes change NNS cord-005646-xhx9pzhj 401 5 ( ( -LRB- cord-005646-xhx9pzhj 401 6 supine supine JJ cord-005646-xhx9pzhj 401 7 to to IN cord-005646-xhx9pzhj 401 8 prone prone JJ cord-005646-xhx9pzhj 401 9 ) ) -RRB- cord-005646-xhx9pzhj 401 10 is be VBZ cord-005646-xhx9pzhj 401 11 a a DT cord-005646-xhx9pzhj 401 12 therapeutic therapeutic JJ cord-005646-xhx9pzhj 401 13 intervention intervention NN cord-005646-xhx9pzhj 401 14 that that WDT cord-005646-xhx9pzhj 401 15 could could MD cord-005646-xhx9pzhj 401 16 be be VB cord-005646-xhx9pzhj 401 17 useful useful JJ cord-005646-xhx9pzhj 401 18 in in IN cord-005646-xhx9pzhj 401 19 children child NNS cord-005646-xhx9pzhj 401 20 with with IN cord-005646-xhx9pzhj 401 21 adult adult JJ cord-005646-xhx9pzhj 401 22 respiratory respiratory JJ cord-005646-xhx9pzhj 401 23 distress distress NN cord-005646-xhx9pzhj 401 24 syndrome syndrome NN cord-005646-xhx9pzhj 401 25 . . . cord-005646-xhx9pzhj 402 1 Objective objective NN cord-005646-xhx9pzhj 402 2 : : : cord-005646-xhx9pzhj 403 1 To to TO cord-005646-xhx9pzhj 403 2 determine determine VB cord-005646-xhx9pzhj 403 3 the the DT cord-005646-xhx9pzhj 403 4 effects effect NNS cord-005646-xhx9pzhj 403 5 of of IN cord-005646-xhx9pzhj 403 6 postural postural JJ cord-005646-xhx9pzhj 403 7 changes change NNS cord-005646-xhx9pzhj 403 8 in in IN cord-005646-xhx9pzhj 403 9 the the DT cord-005646-xhx9pzhj 403 10 oxygenation oxygenation NN cord-005646-xhx9pzhj 403 11 of of IN cord-005646-xhx9pzhj 403 12 young young JJ cord-005646-xhx9pzhj 403 13 children child NNS cord-005646-xhx9pzhj 403 14 with with IN cord-005646-xhx9pzhj 403 15 ARDS ARDS NNP cord-005646-xhx9pzhj 403 16 . . . cord-005646-xhx9pzhj 404 1 Method Method NNP cord-005646-xhx9pzhj 404 2 , , , cord-005646-xhx9pzhj 404 3 s s XX cord-005646-xhx9pzhj 404 4 : : : cord-005646-xhx9pzhj 405 1 A a DT cord-005646-xhx9pzhj 405 2 prospective prospective JJ cord-005646-xhx9pzhj 405 3 stud3 stud3 NN cord-005646-xhx9pzhj 405 4 , , , cord-005646-xhx9pzhj 405 5 " " '' cord-005646-xhx9pzhj 405 6 was be VBD cord-005646-xhx9pzhj 405 7 performed perform VBN cord-005646-xhx9pzhj 405 8 in in IN cord-005646-xhx9pzhj 405 9 eleven eleven CD cord-005646-xhx9pzhj 405 10 subjects subject NNS cord-005646-xhx9pzhj 405 11 aged age VBN cord-005646-xhx9pzhj 405 12 6 6 CD cord-005646-xhx9pzhj 405 13 to to IN cord-005646-xhx9pzhj 405 14 120 120 CD cord-005646-xhx9pzhj 405 15 months month NNS cord-005646-xhx9pzhj 406 1 ( ( -LRB- cord-005646-xhx9pzhj 406 2 mean=33 mean=33 NNP cord-005646-xhx9pzhj 406 3 ) ) -RRB- cord-005646-xhx9pzhj 406 4 with with IN cord-005646-xhx9pzhj 406 5 the the DT cord-005646-xhx9pzhj 406 6 diagnosis diagnosis NN cord-005646-xhx9pzhj 406 7 of of IN cord-005646-xhx9pzhj 406 8 ARDSreceiving ARDSreceiving NNP cord-005646-xhx9pzhj 406 9 vendlatory vendlatory NNP cord-005646-xhx9pzhj 406 10 support support NN cord-005646-xhx9pzhj 406 11 . . . cord-005646-xhx9pzhj 407 1 ( ( -LRB- cord-005646-xhx9pzhj 407 2 mean mean VB cord-005646-xhx9pzhj 407 3 PEEP PEEP NNP cord-005646-xhx9pzhj 407 4 and and CC cord-005646-xhx9pzhj 407 5 FiO2 FiO2 NNS cord-005646-xhx9pzhj 407 6 of of IN cord-005646-xhx9pzhj 407 7 9 9 CD cord-005646-xhx9pzhj 407 8 and and CC cord-005646-xhx9pzhj 407 9 0.75 0.75 CD cord-005646-xhx9pzhj 407 10 respectively respectively RB cord-005646-xhx9pzhj 407 11 ) ) -RRB- cord-005646-xhx9pzhj 407 12 . . . cord-005646-xhx9pzhj 408 1 Postural postural JJ cord-005646-xhx9pzhj 408 2 changes change NNS cord-005646-xhx9pzhj 408 3 was be VBD cord-005646-xhx9pzhj 408 4 performed perform VBN cord-005646-xhx9pzhj 408 5 every every DT cord-005646-xhx9pzhj 408 6 8 8 CD cord-005646-xhx9pzhj 408 7 - - SYM cord-005646-xhx9pzhj 408 8 12 12 CD cord-005646-xhx9pzhj 408 9 hours hour NNS cord-005646-xhx9pzhj 408 10 , , , cord-005646-xhx9pzhj 408 11 during during IN cord-005646-xhx9pzhj 408 12 a a DT cord-005646-xhx9pzhj 408 13 period period NN cord-005646-xhx9pzhj 408 14 of of IN cord-005646-xhx9pzhj 408 15 time time NN cord-005646-xhx9pzhj 408 16 ranging range VBG cord-005646-xhx9pzhj 408 17 from from IN cord-005646-xhx9pzhj 408 18 5 5 CD cord-005646-xhx9pzhj 408 19 to to TO cord-005646-xhx9pzhj 408 20 16 16 CD cord-005646-xhx9pzhj 408 21 days day NNS cord-005646-xhx9pzhj 408 22 . . . cord-005646-xhx9pzhj 409 1 Arterial arterial JJ cord-005646-xhx9pzhj 409 2 blood blood NN cord-005646-xhx9pzhj 409 3 gases gas NNS cord-005646-xhx9pzhj 409 4 were be VBD cord-005646-xhx9pzhj 409 5 determined determine VBN cord-005646-xhx9pzhj 409 6 before before IN cord-005646-xhx9pzhj 409 7 and and CC cord-005646-xhx9pzhj 409 8 30 30 CD cord-005646-xhx9pzhj 409 9 - - SYM cord-005646-xhx9pzhj 409 10 60 60 CD cord-005646-xhx9pzhj 409 11 n n NN cord-005646-xhx9pzhj 409 12 ~ ~ NFP cord-005646-xhx9pzhj 409 13 n n XX cord-005646-xhx9pzhj 409 14 after after IN cord-005646-xhx9pzhj 409 15 the the DT cord-005646-xhx9pzhj 409 16 postural postural JJ cord-005646-xhx9pzhj 409 17 change change NN cord-005646-xhx9pzhj 409 18 , , , cord-005646-xhx9pzhj 409 19 No no DT cord-005646-xhx9pzhj 409 20 modification modification NN cord-005646-xhx9pzhj 409 21 in in IN cord-005646-xhx9pzhj 409 22 the the DT cord-005646-xhx9pzhj 409 23 mechattical mechattical JJ cord-005646-xhx9pzhj 409 24 ventilation ventilation NN cord-005646-xhx9pzhj 409 25 other other JJ cord-005646-xhx9pzhj 409 26 that that IN cord-005646-xhx9pzhj 409 27 changes change NNS cord-005646-xhx9pzhj 409 28 in in IN cord-005646-xhx9pzhj 409 29 the the DT cord-005646-xhx9pzhj 409 30 FiO2 FiO2 NNS cord-005646-xhx9pzhj 409 31 were be VBD cord-005646-xhx9pzhj 409 32 performed perform VBN cord-005646-xhx9pzhj 409 33 . . . cord-005646-xhx9pzhj 410 1 The the DT cord-005646-xhx9pzhj 410 2 oxygenation oxygenation NN cord-005646-xhx9pzhj 410 3 was be VBD cord-005646-xhx9pzhj 410 4 determined determine VBN cord-005646-xhx9pzhj 410 5 by by IN cord-005646-xhx9pzhj 410 6 the the DT cord-005646-xhx9pzhj 410 7 index index NN cord-005646-xhx9pzhj 410 8 PaO2 PaO2 NNS cord-005646-xhx9pzhj 410 9 / / SYM cord-005646-xhx9pzhj 410 10 Fi02 Fi02 NNP cord-005646-xhx9pzhj 411 1 ( ( -LRB- cord-005646-xhx9pzhj 411 2 P p NN cord-005646-xhx9pzhj 411 3 / / SYM cord-005646-xhx9pzhj 411 4 F F NNP cord-005646-xhx9pzhj 411 5 ) ) -RRB- cord-005646-xhx9pzhj 411 6 . . . cord-005646-xhx9pzhj 412 1 To to TO cord-005646-xhx9pzhj 412 2 study study VB cord-005646-xhx9pzhj 412 3 the the DT cord-005646-xhx9pzhj 412 4 differences difference NNS cord-005646-xhx9pzhj 412 5 between between IN cord-005646-xhx9pzhj 412 6 the the DT cord-005646-xhx9pzhj 412 7 oxygenation oxygenation NN cord-005646-xhx9pzhj 412 8 mean mean VB cord-005646-xhx9pzhj 412 9 , , , cord-005646-xhx9pzhj 412 10 before before IN cord-005646-xhx9pzhj 412 11 and and CC cord-005646-xhx9pzhj 412 12 after after IN cord-005646-xhx9pzhj 412 13 the the DT cord-005646-xhx9pzhj 412 14 postural postural JJ cord-005646-xhx9pzhj 412 15 changes change VBZ cord-005646-xhx9pzhj 412 16 the the DT cord-005646-xhx9pzhj 412 17 Wilcoxon Wilcoxon NNP cord-005646-xhx9pzhj 412 18 test test NN cord-005646-xhx9pzhj 412 19 for for IN cord-005646-xhx9pzhj 412 20 paired pair VBN cord-005646-xhx9pzhj 412 21 samples sample NNS cord-005646-xhx9pzhj 412 22 was be VBD cord-005646-xhx9pzhj 412 23 used use VBN cord-005646-xhx9pzhj 412 24 , , , cord-005646-xhx9pzhj 412 25 Results result NNS cord-005646-xhx9pzhj 412 26 : : : cord-005646-xhx9pzhj 412 27 184 184 CD cord-005646-xhx9pzhj 412 28 changes change NNS cord-005646-xhx9pzhj 412 29 were be VBD cord-005646-xhx9pzhj 412 30 performed perform VBN cord-005646-xhx9pzhj 412 31 ( ( -LRB- cord-005646-xhx9pzhj 412 32 104 104 CD cord-005646-xhx9pzhj 412 33 from from IN cord-005646-xhx9pzhj 412 34 supine supine JJ cord-005646-xhx9pzhj 412 35 to to IN cord-005646-xhx9pzhj 412 36 prone prone JJ cord-005646-xhx9pzhj 412 37 and and CC cord-005646-xhx9pzhj 412 38 80 80 CD cord-005646-xhx9pzhj 412 39 from from IN cord-005646-xhx9pzhj 412 40 prone prone JJ cord-005646-xhx9pzhj 412 41 to to IN cord-005646-xhx9pzhj 412 42 supine supine JJ cord-005646-xhx9pzhj 412 43 ) ) -RRB- cord-005646-xhx9pzhj 412 44 . . . cord-005646-xhx9pzhj 413 1 A9 A9 NNP cord-005646-xhx9pzhj 413 2 % % NN cord-005646-xhx9pzhj 413 3 increased increase VBD cord-005646-xhx9pzhj 414 1 P p NN cord-005646-xhx9pzhj 414 2 / / SYM cord-005646-xhx9pzhj 414 3 F f NN cord-005646-xhx9pzhj 414 4 ratio ratio NN cord-005646-xhx9pzhj 414 5 was be VBD cord-005646-xhx9pzhj 414 6 obtained obtain VBN cord-005646-xhx9pzhj 414 7 after after IN cord-005646-xhx9pzhj 414 8 the the DT cord-005646-xhx9pzhj 414 9 change change NN cord-005646-xhx9pzhj 414 10 from from IN cord-005646-xhx9pzhj 414 11 supine supine JJ cord-005646-xhx9pzhj 414 12 to to TO cord-005646-xhx9pzhj 414 13 prune prune VB cord-005646-xhx9pzhj 414 14 . . . cord-005646-xhx9pzhj 415 1 Although although IN cord-005646-xhx9pzhj 415 2 , , , cord-005646-xhx9pzhj 415 3 not not RB cord-005646-xhx9pzhj 415 4 all all PDT cord-005646-xhx9pzhj 415 5 the the DT cord-005646-xhx9pzhj 415 6 patients patient NNS cord-005646-xhx9pzhj 415 7 receiving receive VBG cord-005646-xhx9pzhj 415 8 postural postural JJ cord-005646-xhx9pzhj 415 9 changes change NNS cord-005646-xhx9pzhj 415 10 improved improve VBD cord-005646-xhx9pzhj 415 11 their -PRON- PRP$ cord-005646-xhx9pzhj 415 12 P p NN cord-005646-xhx9pzhj 415 13 / / SYM cord-005646-xhx9pzhj 415 14 F. F. NNP cord-005646-xhx9pzhj 415 15 Six six CD cord-005646-xhx9pzhj 415 16 of of IN cord-005646-xhx9pzhj 415 17 them -PRON- PRP cord-005646-xhx9pzhj 415 18 ( ( -LRB- cord-005646-xhx9pzhj 415 19 Group Group NNP cord-005646-xhx9pzhj 415 20 I I NNP cord-005646-xhx9pzhj 415 21 ) ) -RRB- cord-005646-xhx9pzhj 415 22 showed show VBD cord-005646-xhx9pzhj 415 23 an an DT cord-005646-xhx9pzhj 415 24 improve improve NN cord-005646-xhx9pzhj 415 25 in in IN cord-005646-xhx9pzhj 415 26 the the DT cord-005646-xhx9pzhj 415 27 P p NN cord-005646-xhx9pzhj 415 28 / / SYM cord-005646-xhx9pzhj 415 29 F f NN cord-005646-xhx9pzhj 415 30 when when WRB cord-005646-xhx9pzhj 415 31 changed change VBD cord-005646-xhx9pzhj 415 32 from from IN cord-005646-xhx9pzhj 415 33 supine supine JJ cord-005646-xhx9pzhj 415 34 to to IN cord-005646-xhx9pzhj 415 35 prone prone JJ cord-005646-xhx9pzhj 415 36 , , , cord-005646-xhx9pzhj 415 37 returning return VBG cord-005646-xhx9pzhj 415 38 to to IN cord-005646-xhx9pzhj 415 39 their -PRON- PRP$ cord-005646-xhx9pzhj 415 40 base base NN cord-005646-xhx9pzhj 415 41 line line NN cord-005646-xhx9pzhj 415 42 when when WRB cord-005646-xhx9pzhj 415 43 positioned position VBN cord-005646-xhx9pzhj 415 44 from from IN cord-005646-xhx9pzhj 415 45 prone prone JJ cord-005646-xhx9pzhj 415 46 to to IN cord-005646-xhx9pzhj 415 47 supine supine JJ cord-005646-xhx9pzhj 415 48 . . . cord-005646-xhx9pzhj 416 1 No no DT cord-005646-xhx9pzhj 416 2 improvement improvement NN cord-005646-xhx9pzhj 416 3 on on IN cord-005646-xhx9pzhj 416 4 the the DT cord-005646-xhx9pzhj 416 5 P p NN cord-005646-xhx9pzhj 416 6 / / SYM cord-005646-xhx9pzhj 416 7 F F NNP cord-005646-xhx9pzhj 416 8 was be VBD cord-005646-xhx9pzhj 416 9 observed observe VBN cord-005646-xhx9pzhj 416 10 in in IN cord-005646-xhx9pzhj 416 11 the the DT cord-005646-xhx9pzhj 416 12 remaining remain VBG cord-005646-xhx9pzhj 416 13 5 5 CD cord-005646-xhx9pzhj 416 14 subjects subject NNS cord-005646-xhx9pzhj 416 15 ( ( -LRB- cord-005646-xhx9pzhj 416 16 Group Group NNP cord-005646-xhx9pzhj 416 17 II)after II)after NNP cord-005646-xhx9pzhj 416 18 postural postural JJ cord-005646-xhx9pzhj 416 19 changes change NNS cord-005646-xhx9pzhj 416 20 ( ( -LRB- cord-005646-xhx9pzhj 416 21 Table table NN cord-005646-xhx9pzhj 416 22 1 1 CD cord-005646-xhx9pzhj 416 23 ) ) -RRB- cord-005646-xhx9pzhj 416 24 . . . cord-005646-xhx9pzhj 417 1 During during IN cord-005646-xhx9pzhj 417 2 the the DT cord-005646-xhx9pzhj 417 3 maneuver maneuver NN cord-005646-xhx9pzhj 417 4 no no DT cord-005646-xhx9pzhj 417 5 complications complication NNS cord-005646-xhx9pzhj 417 6 were be VBD cord-005646-xhx9pzhj 417 7 observed observe VBN cord-005646-xhx9pzhj 417 8 . . . cord-005646-xhx9pzhj 418 1 Two two CD cord-005646-xhx9pzhj 418 2 patients patient NNS cord-005646-xhx9pzhj 418 3 had have VBD cord-005646-xhx9pzhj 418 4 a a DT cord-005646-xhx9pzhj 418 5 pneumothorax pneumothorax NN cord-005646-xhx9pzhj 418 6 , , , cord-005646-xhx9pzhj 418 7 not not RB cord-005646-xhx9pzhj 418 8 related relate VBN cord-005646-xhx9pzhj 418 9 with with IN cord-005646-xhx9pzhj 418 10 the the DT cord-005646-xhx9pzhj 418 11 postural postural JJ cord-005646-xhx9pzhj 418 12 change change NN cord-005646-xhx9pzhj 418 13 . . . cord-005646-xhx9pzhj 419 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 419 2 : : : cord-005646-xhx9pzhj 420 1 Postural postural JJ cord-005646-xhx9pzhj 420 2 changes change NNS cord-005646-xhx9pzhj 420 3 ( ( -LRB- cord-005646-xhx9pzhj 420 4 supine supine JJ cord-005646-xhx9pzhj 420 5 to to IN cord-005646-xhx9pzhj 420 6 prone prone JJ cord-005646-xhx9pzhj 420 7 ) ) -RRB- cord-005646-xhx9pzhj 420 8 is be VBZ cord-005646-xhx9pzhj 420 9 an an DT cord-005646-xhx9pzhj 420 10 easy easy JJ cord-005646-xhx9pzhj 420 11 way way NN cord-005646-xhx9pzhj 420 12 to to TO cord-005646-xhx9pzhj 420 13 improve improve VB cord-005646-xhx9pzhj 420 14 oxygenation oxygenation NN cord-005646-xhx9pzhj 420 15 in in IN cord-005646-xhx9pzhj 420 16 some some DT cord-005646-xhx9pzhj 420 17 children child NNS cord-005646-xhx9pzhj 420 18 with with IN cord-005646-xhx9pzhj 420 19 ARDS ARDS NNP cord-005646-xhx9pzhj 420 20 . . . cord-005646-xhx9pzhj 421 1 Change change VB cord-005646-xhx9pzhj 421 2 to to IN cord-005646-xhx9pzhj 421 3 prone prone JJ cord-005646-xhx9pzhj 421 4 Change change NN cord-005646-xhx9pzhj 421 5 to to IN cord-005646-xhx9pzhj 421 6 supine supine JJ cord-005646-xhx9pzhj 421 7 Introduction introduction NN cord-005646-xhx9pzhj 421 8 : : : cord-005646-xhx9pzhj 422 1 The the DT cord-005646-xhx9pzhj 422 2 common common JJ cord-005646-xhx9pzhj 422 3 noninvasive noninvasive JJ cord-005646-xhx9pzhj 422 4 diagnostic diagnostic JJ cord-005646-xhx9pzhj 422 5 efforts effort NNS cord-005646-xhx9pzhj 422 6 to to TO cord-005646-xhx9pzhj 422 7 identify identify VB cord-005646-xhx9pzhj 422 8 possible possible JJ cord-005646-xhx9pzhj 422 9 obstruction obstruction NN cord-005646-xhx9pzhj 422 10 of of IN cord-005646-xhx9pzhj 422 11 the the DT cord-005646-xhx9pzhj 422 12 intrathorucic intrathorucic NNP cord-005646-xhx9pzhj 422 13 airway airway NNP cord-005646-xhx9pzhj 422 14 , , , cord-005646-xhx9pzhj 422 15 are be VBP cord-005646-xhx9pzhj 422 16 of of IN cord-005646-xhx9pzhj 422 17 limited limited JJ cord-005646-xhx9pzhj 422 18 value value NN cord-005646-xhx9pzhj 422 19 . . . cord-005646-xhx9pzhj 423 1 Invasive invasive JJ cord-005646-xhx9pzhj 423 2 procedures procedure NNS cord-005646-xhx9pzhj 423 3 such such JJ cord-005646-xhx9pzhj 423 4 as as IN cord-005646-xhx9pzhj 423 5 bronchoscopy bronchoscopy NN cord-005646-xhx9pzhj 423 6 and and CC cord-005646-xhx9pzhj 423 7 bronchography bronchography NN cord-005646-xhx9pzhj 423 8 may may MD cord-005646-xhx9pzhj 423 9 also also RB cord-005646-xhx9pzhj 423 10 be be VB cord-005646-xhx9pzhj 423 11 noncontributory noncontributory JJ cord-005646-xhx9pzhj 423 12 and and CC cord-005646-xhx9pzhj 423 13 entail entail VB cord-005646-xhx9pzhj 423 14 risks risk NNS cord-005646-xhx9pzhj 423 15 . . . cord-005646-xhx9pzhj 424 1 We -PRON- PRP cord-005646-xhx9pzhj 424 2 evaluated evaluate VBD cord-005646-xhx9pzhj 424 3 the the DT cord-005646-xhx9pzhj 424 4 usefulness usefulness NN cord-005646-xhx9pzhj 424 5 of of IN cord-005646-xhx9pzhj 424 6 3D 3D NNP cord-005646-xhx9pzhj 424 7 - - HYPH cord-005646-xhx9pzhj 424 8 CT CT NNP cord-005646-xhx9pzhj 424 9 in in IN cord-005646-xhx9pzhj 424 10 the the DT cord-005646-xhx9pzhj 424 11 diagnosis diagnosis NN cord-005646-xhx9pzhj 424 12 and and CC cord-005646-xhx9pzhj 424 13 management management NN cord-005646-xhx9pzhj 424 14 of of IN cord-005646-xhx9pzhj 424 15 pediatric pediatric JJ cord-005646-xhx9pzhj 424 16 patients patient NNS cord-005646-xhx9pzhj 424 17 with with IN cord-005646-xhx9pzhj 424 18 suspected suspect VBN cord-005646-xhx9pzhj 424 19 intrathoracic intrathoracic JJ cord-005646-xhx9pzhj 424 20 airway airway NN cord-005646-xhx9pzhj 424 21 obstruction obstruction NN cord-005646-xhx9pzhj 424 22 ( ( -LRB- cord-005646-xhx9pzhj 424 23 ITAO ITAO NNP cord-005646-xhx9pzhj 424 24 ) ) -RRB- cord-005646-xhx9pzhj 424 25 . . . cord-005646-xhx9pzhj 425 1 Methods method NNS cord-005646-xhx9pzhj 425 2 : : : cord-005646-xhx9pzhj 426 1 We -PRON- PRP cord-005646-xhx9pzhj 426 2 used use VBD cord-005646-xhx9pzhj 426 3 a a DT cord-005646-xhx9pzhj 426 4 diagnostic diagnostic JJ cord-005646-xhx9pzhj 426 5 algorithm algorithm NN cord-005646-xhx9pzhj 426 6 ( ( -LRB- cord-005646-xhx9pzhj 426 7 see see VB cord-005646-xhx9pzhj 426 8 diagram diagram NN cord-005646-xhx9pzhj 426 9 ) ) -RRB- cord-005646-xhx9pzhj 426 10 in in IN cord-005646-xhx9pzhj 426 11 patients patient NNS cord-005646-xhx9pzhj 426 12 with with IN cord-005646-xhx9pzhj 426 13 suspected suspect VBN cord-005646-xhx9pzhj 426 14 ITAO ITAO NNP cord-005646-xhx9pzhj 426 15 resulting result VBG cord-005646-xhx9pzhj 426 16 in in IN cord-005646-xhx9pzhj 426 17 respiratory respiratory JJ cord-005646-xhx9pzhj 426 18 distress distress NN cord-005646-xhx9pzhj 426 19 . . . cord-005646-xhx9pzhj 427 1 Three three CD cord-005646-xhx9pzhj 427 2 - - HYPH cord-005646-xhx9pzhj 427 3 dimensioual dimensioual NN cord-005646-xhx9pzhj 427 4 imaging imaging NN cord-005646-xhx9pzhj 427 5 of of IN cord-005646-xhx9pzhj 427 6 the the DT cord-005646-xhx9pzhj 427 7 tracheobronchial tracheobronchial JJ cord-005646-xhx9pzhj 427 8 tree tree NN cord-005646-xhx9pzhj 427 9 was be VBD cord-005646-xhx9pzhj 427 10 reconstructed reconstruct VBN cord-005646-xhx9pzhj 427 11 , , , cord-005646-xhx9pzhj 427 12 following follow VBG cord-005646-xhx9pzhj 427 13 high high JJ cord-005646-xhx9pzhj 427 14 speed speed NN cord-005646-xhx9pzhj 427 15 spiral spiral JJ cord-005646-xhx9pzhj 427 16 CT CT NNP cord-005646-xhx9pzhj 427 17 scan scan NN cord-005646-xhx9pzhj 427 18 , , , cord-005646-xhx9pzhj 427 19 by by IN cord-005646-xhx9pzhj 427 20 specific specific JJ cord-005646-xhx9pzhj 427 21 computer computer NN cord-005646-xhx9pzhj 427 22 software software NN cord-005646-xhx9pzhj 428 1 ( ( -LRB- cord-005646-xhx9pzhj 428 2 Advantage Advantage NNP cord-005646-xhx9pzhj 428 3 Window Window NNP cord-005646-xhx9pzhj 428 4 Computer Computer NNP cord-005646-xhx9pzhj 428 5 Work Work NNP cord-005646-xhx9pzhj 428 6 Station Station NNP cord-005646-xhx9pzhj 428 7 , , , cord-005646-xhx9pzhj 428 8 General General NNP cord-005646-xhx9pzhj 428 9 Electric Electric NNP cord-005646-xhx9pzhj 428 10 , , , cord-005646-xhx9pzhj 428 11 Milwaukee Milwaukee NNP cord-005646-xhx9pzhj 428 12 , , , cord-005646-xhx9pzhj 428 13 Wisconsin Wisconsin NNP cord-005646-xhx9pzhj 428 14 ) ) -RRB- cord-005646-xhx9pzhj 428 15 . . . cord-005646-xhx9pzhj 429 1 Non non JJ cord-005646-xhx9pzhj 429 2 - - JJ cord-005646-xhx9pzhj 429 3 ionic ionic JJ cord-005646-xhx9pzhj 429 4 contrast contrast NN cord-005646-xhx9pzhj 429 5 medium medium NN cord-005646-xhx9pzhj 429 6 was be VBD cord-005646-xhx9pzhj 429 7 injected inject VBN cord-005646-xhx9pzhj 429 8 , , , cord-005646-xhx9pzhj 429 9 in in IN cord-005646-xhx9pzhj 429 10 some some DT cord-005646-xhx9pzhj 429 11 patients patient NNS cord-005646-xhx9pzhj 429 12 , , , cord-005646-xhx9pzhj 429 13 to to TO cord-005646-xhx9pzhj 429 14 delineate delineate VB cord-005646-xhx9pzhj 429 15 the the DT cord-005646-xhx9pzhj 429 16 intrathoracie intrathoracie NN cord-005646-xhx9pzhj 429 17 large large JJ cord-005646-xhx9pzhj 429 18 vessels vessel NNS cord-005646-xhx9pzhj 429 19 .. .. . cord-005646-xhx9pzhj 430 1 Results result NNS cord-005646-xhx9pzhj 430 2 : : : cord-005646-xhx9pzhj 431 1 Eight eight CD cord-005646-xhx9pzhj 431 2 patients patient NNS cord-005646-xhx9pzhj 431 3 were be VBD cord-005646-xhx9pzhj 431 4 studied study VBN cord-005646-xhx9pzhj 431 5 . . . cord-005646-xhx9pzhj 432 1 In in IN cord-005646-xhx9pzhj 432 2 5 5 CD cord-005646-xhx9pzhj 432 3 patients patient NNS cord-005646-xhx9pzhj 432 4 the the DT cord-005646-xhx9pzhj 432 5 3D 3D NNP cord-005646-xhx9pzhj 432 6 - - HYPH cord-005646-xhx9pzhj 432 7 CT CT NNP cord-005646-xhx9pzhj 432 8 revealed reveal VBD cord-005646-xhx9pzhj 432 9 intrathoracic intrathoracic JJ cord-005646-xhx9pzhj 432 10 airway airway NN cord-005646-xhx9pzhj 432 11 abnormalities abnormality NNS cord-005646-xhx9pzhj 432 12 . . . cord-005646-xhx9pzhj 433 1 These these DT cord-005646-xhx9pzhj 433 2 patients patient NNS cord-005646-xhx9pzhj 433 3 underwent undergo VBD cord-005646-xhx9pzhj 433 4 further further JJ cord-005646-xhx9pzhj 433 5 invesive invesive JJ cord-005646-xhx9pzhj 433 6 studies study NNS cord-005646-xhx9pzhj 433 7 which which WDT cord-005646-xhx9pzhj 433 8 confirmed confirm VBD cord-005646-xhx9pzhj 433 9 the the DT cord-005646-xhx9pzhj 433 10 following follow VBG cord-005646-xhx9pzhj 433 11 diagnoses diagnosis NNS cord-005646-xhx9pzhj 433 12 : : : cord-005646-xhx9pzhj 433 13 2 2 CD cord-005646-xhx9pzhj 433 14 patients patient NNS cord-005646-xhx9pzhj 433 15 had have VBD cord-005646-xhx9pzhj 433 16 bronchomalacia bronchomalacia NNS cord-005646-xhx9pzhj 433 17 , , , cord-005646-xhx9pzhj 433 18 1 1 CD cord-005646-xhx9pzhj 433 19 had have VBD cord-005646-xhx9pzhj 433 20 bronchial bronchial JJ cord-005646-xhx9pzhj 433 21 stennsis stennsis NN cord-005646-xhx9pzhj 433 22 due due JJ cord-005646-xhx9pzhj 433 23 to to IN cord-005646-xhx9pzhj 433 24 a a DT cord-005646-xhx9pzhj 433 25 dilated dilated JJ cord-005646-xhx9pzhj 433 26 pulmonary pulmonary JJ cord-005646-xhx9pzhj 433 27 artery artery NN cord-005646-xhx9pzhj 433 28 mad mad JJ cord-005646-xhx9pzhj 434 1 2 2 CD cord-005646-xhx9pzhj 434 2 patients patient NNS cord-005646-xhx9pzhj 434 3 had have VBD cord-005646-xhx9pzhj 434 4 subglottie subglottie NN cord-005646-xhx9pzhj 434 5 stenosis stenosis NN cord-005646-xhx9pzhj 434 6 extending extend VBG cord-005646-xhx9pzhj 434 7 to to IN cord-005646-xhx9pzhj 434 8 the the DT cord-005646-xhx9pzhj 434 9 thoracic thoracic JJ cord-005646-xhx9pzhj 434 10 cavity cavity NN cord-005646-xhx9pzhj 434 11 . . . cord-005646-xhx9pzhj 435 1 Three three CD cord-005646-xhx9pzhj 435 2 patients patient NNS cord-005646-xhx9pzhj 435 3 had have VBD cord-005646-xhx9pzhj 435 4 no no DT cord-005646-xhx9pzhj 435 5 significant significant JJ cord-005646-xhx9pzhj 435 6 disruption disruption NN cord-005646-xhx9pzhj 435 7 in in IN cord-005646-xhx9pzhj 435 8 the the DT cord-005646-xhx9pzhj 435 9 configuration configuration NN cord-005646-xhx9pzhj 435 10 of of IN cord-005646-xhx9pzhj 435 11 the the DT cord-005646-xhx9pzhj 435 12 tracheobronchial tracheobronchial JJ cord-005646-xhx9pzhj 435 13 tree tree NN cord-005646-xhx9pzhj 435 14 and and CC cord-005646-xhx9pzhj 435 15 thus thus RB cord-005646-xhx9pzhj 435 16 did do VBD cord-005646-xhx9pzhj 435 17 not not RB cord-005646-xhx9pzhj 435 18 require require VB cord-005646-xhx9pzhj 435 19 invasive invasive JJ cord-005646-xhx9pzhj 435 20 diagnostic diagnostic JJ cord-005646-xhx9pzhj 435 21 procedures procedure NNS cord-005646-xhx9pzhj 435 22 . . . cord-005646-xhx9pzhj 436 1 Conclusion conclusion NN cord-005646-xhx9pzhj 436 2 : : : cord-005646-xhx9pzhj 437 1 Computer computer NN cord-005646-xhx9pzhj 437 2 reconstruction reconstruction NN cord-005646-xhx9pzhj 437 3 of of IN cord-005646-xhx9pzhj 437 4 three three CD cord-005646-xhx9pzhj 437 5 dimensional dimensional JJ cord-005646-xhx9pzhj 437 6 images image NNS cord-005646-xhx9pzhj 437 7 of of IN cord-005646-xhx9pzhj 437 8 the the DT cord-005646-xhx9pzhj 437 9 tracheobronehial tracheobronehial JJ cord-005646-xhx9pzhj 437 10 tree tree NN cord-005646-xhx9pzhj 437 11 is be VBZ cord-005646-xhx9pzhj 437 12 a a DT cord-005646-xhx9pzhj 437 13 safe safe JJ cord-005646-xhx9pzhj 437 14 and and CC cord-005646-xhx9pzhj 437 15 reliable reliable JJ cord-005646-xhx9pzhj 437 16 diagnostic diagnostic JJ cord-005646-xhx9pzhj 437 17 tool tool NN cord-005646-xhx9pzhj 437 18 for for IN cord-005646-xhx9pzhj 437 19 ITAO ITAO NNP cord-005646-xhx9pzhj 437 20 . . . cord-005646-xhx9pzhj 438 1 ARDS ARDS NNP cord-005646-xhx9pzhj 438 2 and and CC cord-005646-xhx9pzhj 438 3 ECMO ECMO NNP cord-005646-xhx9pzhj 438 4 ; ; : cord-005646-xhx9pzhj 438 5 preliminary preliminary JJ cord-005646-xhx9pzhj 438 6 data datum NNS cord-005646-xhx9pzhj 438 7 from from IN cord-005646-xhx9pzhj 438 8 a a DT cord-005646-xhx9pzhj 438 9 randomized randomized JJ cord-005646-xhx9pzhj 438 10 clinical clinical JJ cord-005646-xhx9pzhj 438 11 trial trial NN cord-005646-xhx9pzhj 438 12 . . . cord-005646-xhx9pzhj 439 1 J J NNP cord-005646-xhx9pzhj 439 2 Fackler Fackler NNP cord-005646-xhx9pzhj 439 3 , , , cord-005646-xhx9pzhj 439 4 C C NNP cord-005646-xhx9pzhj 439 5 Steinhart Steinhart NNP cord-005646-xhx9pzhj 439 6 , , , cord-005646-xhx9pzhj 439 7 D D NNP cord-005646-xhx9pzhj 439 8 Nichols Nichols NNP cord-005646-xhx9pzhj 439 9 , , , cord-005646-xhx9pzhj 439 10 D D NNP cord-005646-xhx9pzhj 439 11 Bohn Bohn NNP cord-005646-xhx9pzhj 439 12 , , , cord-005646-xhx9pzhj 439 13 M M NNP cord-005646-xhx9pzhj 439 14 Heulitt Heulitt NNP cord-005646-xhx9pzhj 439 15 , , , cord-005646-xhx9pzhj 439 16 T T NNP cord-005646-xhx9pzhj 439 17 Green Green NNP cord-005646-xhx9pzhj 439 18 , , , cord-005646-xhx9pzhj 439 19 L L NNP cord-005646-xhx9pzhj 439 20 Martin Martin NNP cord-005646-xhx9pzhj 439 21 , , , cord-005646-xhx9pzhj 439 22 K K NNP cord-005646-xhx9pzhj 439 23 Newth Newth NNP cord-005646-xhx9pzhj 439 24 , , , cord-005646-xhx9pzhj 439 25 M M NNP cord-005646-xhx9pzhj 439 26 Klein Klein NNP cord-005646-xhx9pzhj 439 27 , , , cord-005646-xhx9pzhj 439 28 J J NNP cord-005646-xhx9pzhj 439 29 Ware Ware NNP cord-005646-xhx9pzhj 439 30 . . . cord-005646-xhx9pzhj 440 1 Many many JJ cord-005646-xhx9pzhj 440 2 suggest suggest VBP cord-005646-xhx9pzhj 440 3 ECMO ECMO NNP cord-005646-xhx9pzhj 440 4 be be VB cord-005646-xhx9pzhj 440 5 considered consider VBN cord-005646-xhx9pzhj 440 6 experimental experimental JJ cord-005646-xhx9pzhj 440 7 for for IN cord-005646-xhx9pzhj 440 8 ARDS ARDS NNP cord-005646-xhx9pzhj 440 9 and and CC cord-005646-xhx9pzhj 440 10 undertaken undertake VBN cord-005646-xhx9pzhj 440 11 only only RB cord-005646-xhx9pzhj 440 12 with with IN cord-005646-xhx9pzhj 440 13 careful careful JJ cord-005646-xhx9pzhj 440 14 data data NN cord-005646-xhx9pzhj 440 15 collection collection NN cord-005646-xhx9pzhj 440 16 and and CC cord-005646-xhx9pzhj 440 17 reporting reporting NN cord-005646-xhx9pzhj 440 18 . . . cord-005646-xhx9pzhj 441 1 A a DT cord-005646-xhx9pzhj 441 2 mtflticenter mtflticenter NN cord-005646-xhx9pzhj 441 3 pediatric pediatric JJ cord-005646-xhx9pzhj 441 4 RCT RCT NNP cord-005646-xhx9pzhj 441 5 is be VBZ cord-005646-xhx9pzhj 441 6 in in IN cord-005646-xhx9pzhj 441 7 progress progress NN cord-005646-xhx9pzhj 441 8 to to TO cord-005646-xhx9pzhj 441 9 determine determine VB cord-005646-xhx9pzhj 441 10 whether whether IN cord-005646-xhx9pzhj 441 11 1 1 CD cord-005646-xhx9pzhj 441 12 ) ) -RRB- cord-005646-xhx9pzhj 441 13 ECMO ecmo NN cord-005646-xhx9pzhj 441 14 and/or and/or CC cord-005646-xhx9pzhj 441 15 2 2 CD cord-005646-xhx9pzhj 441 16 ) ) -RRB- cord-005646-xhx9pzhj 441 17 permissive permissive JJ cord-005646-xhx9pzhj 441 18 hypercapnia hypercapnia NN cord-005646-xhx9pzhj 441 19 , , , cord-005646-xhx9pzhj 441 20 offer offer VBP cord-005646-xhx9pzhj 441 21 significant significant JJ cord-005646-xhx9pzhj 441 22 advantage advantage NN cord-005646-xhx9pzhj 441 23 for for IN cord-005646-xhx9pzhj 441 24 the the DT cord-005646-xhx9pzhj 441 25 treatment treatment NN cord-005646-xhx9pzhj 441 26 of of IN cord-005646-xhx9pzhj 441 27 ARDS ARDS NNP cord-005646-xhx9pzhj 441 28 . . . cord-005646-xhx9pzhj 442 1 Methods method NNS cord-005646-xhx9pzhj 442 2 : : : cord-005646-xhx9pzhj 443 1 All all DT cord-005646-xhx9pzhj 443 2 patients patient NNS cord-005646-xhx9pzhj 443 3 aged age VBN cord-005646-xhx9pzhj 443 4 2 2 CD cord-005646-xhx9pzhj 443 5 wk wk NN cord-005646-xhx9pzhj 443 6 to to IN cord-005646-xhx9pzhj 443 7 18 18 CD cord-005646-xhx9pzhj 443 8 yr yr NN cord-005646-xhx9pzhj 443 9 ( ( -LRB- cord-005646-xhx9pzhj 443 10 without without IN cord-005646-xhx9pzhj 443 11 congenital congenital JJ cord-005646-xhx9pzhj 443 12 heart heart NN cord-005646-xhx9pzhj 443 13 disease disease NN cord-005646-xhx9pzhj 443 14 ) ) -RRB- cord-005646-xhx9pzhj 443 15 are be VBP cord-005646-xhx9pzhj 443 16 eligible eligible JJ cord-005646-xhx9pzhj 443 17 for for IN cord-005646-xhx9pzhj 443 18 study study NN cord-005646-xhx9pzhj 443 19 . . . cord-005646-xhx9pzhj 444 1 Data datum NNS cord-005646-xhx9pzhj 444 2 collection collection NN cord-005646-xhx9pzhj 444 3 begins begin VBZ cord-005646-xhx9pzhj 444 4 when when WRB cord-005646-xhx9pzhj 444 5 a a DT cord-005646-xhx9pzhj 444 6 patient patient NN cord-005646-xhx9pzhj 444 7 receives receive VBZ cord-005646-xhx9pzhj 444 8 at at RB cord-005646-xhx9pzhj 444 9 least least JJS cord-005646-xhx9pzhj 444 10 50 50 CD cord-005646-xhx9pzhj 444 11 % % NN cord-005646-xhx9pzhj 444 12 oxygen oxygen NN cord-005646-xhx9pzhj 444 13 and and CC cord-005646-xhx9pzhj 444 14 a a DT cord-005646-xhx9pzhj 444 15 PEEP peep NN cord-005646-xhx9pzhj 444 16 of of IN cord-005646-xhx9pzhj 444 17 6 6 CD cord-005646-xhx9pzhj 444 18 cm cm NN cord-005646-xhx9pzhj 444 19 H20 h20 NN cord-005646-xhx9pzhj 444 20 for for IN cord-005646-xhx9pzhj 444 21 12 12 CD cord-005646-xhx9pzhj 444 22 hours hour NNS cord-005646-xhx9pzhj 444 23 ( ( -LRB- cord-005646-xhx9pzhj 444 24 stage stage NN cord-005646-xhx9pzhj 444 25 t t NNP cord-005646-xhx9pzhj 444 26 ) ) -RRB- cord-005646-xhx9pzhj 444 27 . . . cord-005646-xhx9pzhj 445 1 If if IN cord-005646-xhx9pzhj 445 2 the the DT cord-005646-xhx9pzhj 445 3 predicted predict VBN cord-005646-xhx9pzhj 445 4 mortality mortality NN cord-005646-xhx9pzhj 445 5 reaches reach VBZ cord-005646-xhx9pzhj 445 6 60 60 CD cord-005646-xhx9pzhj 445 7 % % NN cord-005646-xhx9pzhj 445 8 within within IN cord-005646-xhx9pzhj 445 9 7 7 CD cord-005646-xhx9pzhj 445 10 days day NNS cord-005646-xhx9pzhj 445 11 ( ( -LRB- cord-005646-xhx9pzhj 445 12 stage stage NN cord-005646-xhx9pzhj 445 13 2 2 CD cord-005646-xhx9pzhj 445 14 ) ) -RRB- cord-005646-xhx9pzhj 445 15 , , , cord-005646-xhx9pzhj 445 16 eligible eligible JJ cord-005646-xhx9pzhj 445 17 patients patient NNS cord-005646-xhx9pzhj 445 18 are be VBP cord-005646-xhx9pzhj 445 19 asked ask VBN cord-005646-xhx9pzhj 445 20 for for IN cord-005646-xhx9pzhj 445 21 written write VBN cord-005646-xhx9pzhj 445 22 consent consent NN cord-005646-xhx9pzhj 445 23 for for IN cord-005646-xhx9pzhj 445 24 randomization randomization NN cord-005646-xhx9pzhj 445 25 . . . cord-005646-xhx9pzhj 446 1 Patients patient NNS cord-005646-xhx9pzhj 446 2 are be VBP cord-005646-xhx9pzhj 446 3 excluded exclude VBN cord-005646-xhx9pzhj 446 4 from from IN cord-005646-xhx9pzhj 446 5 randomization randomization NN cord-005646-xhx9pzhj 446 6 with with IN cord-005646-xhx9pzhj 446 7 significant significant JJ cord-005646-xhx9pzhj 446 8 chronic chronic JJ cord-005646-xhx9pzhj 446 9 lung lung NN cord-005646-xhx9pzhj 446 10 disease disease NN cord-005646-xhx9pzhj 446 11 , , , cord-005646-xhx9pzhj 446 12 immune immune JJ cord-005646-xhx9pzhj 446 13 compromise compromise NN cord-005646-xhx9pzhj 446 14 , , , cord-005646-xhx9pzhj 446 15 cardiac cardiac JJ cord-005646-xhx9pzhj 446 16 disease disease NN cord-005646-xhx9pzhj 446 17 ; ; : cord-005646-xhx9pzhj 446 18 or or CC cord-005646-xhx9pzhj 446 19 profound profound JJ cord-005646-xhx9pzhj 446 20 acute acute JJ cord-005646-xhx9pzhj 446 21 central central JJ cord-005646-xhx9pzhj 446 22 nervous nervous JJ cord-005646-xhx9pzhj 446 23 system system NN cord-005646-xhx9pzhj 446 24 damage damage NN cord-005646-xhx9pzhj 446 25 . . . cord-005646-xhx9pzhj 447 1 The the DT cord-005646-xhx9pzhj 447 2 prime prime JJ cord-005646-xhx9pzhj 447 3 outcome outcome NN cord-005646-xhx9pzhj 447 4 variable variable NN cord-005646-xhx9pzhj 447 5 is be VBZ cord-005646-xhx9pzhj 447 6 survival survival NN cord-005646-xhx9pzhj 447 7 . . . cord-005646-xhx9pzhj 448 1 At at IN cord-005646-xhx9pzhj 448 2 the the DT cord-005646-xhx9pzhj 448 3 studies study NNS cord-005646-xhx9pzhj 448 4 onset onset NN cord-005646-xhx9pzhj 448 5 , , , cord-005646-xhx9pzhj 448 6 400 400 CD cord-005646-xhx9pzhj 448 7 pts pt NNS cord-005646-xhx9pzhj 448 8 were be VBD cord-005646-xhx9pzhj 448 9 estimated estimate VBN cord-005646-xhx9pzhj 448 10 to to TO cord-005646-xhx9pzhj 448 11 be be VB cord-005646-xhx9pzhj 448 12 required require VBN cord-005646-xhx9pzhj 448 13 so so IN cord-005646-xhx9pzhj 448 14 that that IN cord-005646-xhx9pzhj 448 15 65 65 CD cord-005646-xhx9pzhj 448 16 pts pt NNS cord-005646-xhx9pzhj 448 17 were be VBD cord-005646-xhx9pzhj 448 18 randomized randomize VBN cord-005646-xhx9pzhj 448 19 per per IN cord-005646-xhx9pzhj 448 20 arm arm NN cord-005646-xhx9pzhj 448 21 . . . cord-005646-xhx9pzhj 449 1 Results result NNS cord-005646-xhx9pzhj 449 2 : : : cord-005646-xhx9pzhj 450 1 131 131 CD cord-005646-xhx9pzhj 450 2 patients patient NNS cord-005646-xhx9pzhj 450 3 are be VBP cord-005646-xhx9pzhj 450 4 enrolled enrol VBN cord-005646-xhx9pzhj 450 5 from from IN cord-005646-xhx9pzhj 450 6 9 9 CD cord-005646-xhx9pzhj 450 7 centers center NNS cord-005646-xhx9pzhj 450 8 . . . cord-005646-xhx9pzhj 451 1 Data datum NNS cord-005646-xhx9pzhj 451 2 are be VBP cord-005646-xhx9pzhj 451 3 complete complete JJ cord-005646-xhx9pzhj 451 4 on on IN cord-005646-xhx9pzhj 451 5 85 85 CD cord-005646-xhx9pzhj 451 6 . . . cord-005646-xhx9pzhj 452 1 66 66 CD cord-005646-xhx9pzhj 452 2 patients patient NNS cord-005646-xhx9pzhj 452 3 never never RB cord-005646-xhx9pzhj 452 4 reached reach VBD cord-005646-xhx9pzhj 452 5 Stage stage NN cord-005646-xhx9pzhj 452 6 2 2 CD cord-005646-xhx9pzhj 452 7 ( ( -LRB- cord-005646-xhx9pzhj 452 8 i.e. i.e. FW cord-005646-xhx9pzhj 452 9 60 60 CD cord-005646-xhx9pzhj 452 10 % % NN cord-005646-xhx9pzhj 452 11 mortality mortality NN cord-005646-xhx9pzhj 452 12 ) ) -RRB- cord-005646-xhx9pzhj 452 13 . . . cord-005646-xhx9pzhj 453 1 47 47 CD cord-005646-xhx9pzhj 453 2 patients patient NNS cord-005646-xhx9pzhj 453 3 improved improve VBN cord-005646-xhx9pzhj 453 4 and and CC cord-005646-xhx9pzhj 453 5 19 19 CD cord-005646-xhx9pzhj 453 6 died die VBD cord-005646-xhx9pzhj 453 7 . . . cord-005646-xhx9pzhj 454 1 Of of IN cord-005646-xhx9pzhj 454 2 the the DT cord-005646-xhx9pzhj 454 3 latter latter JJ cord-005646-xhx9pzhj 454 4 , , , cord-005646-xhx9pzhj 454 5 13 13 CD cord-005646-xhx9pzhj 454 6 had have VBD cord-005646-xhx9pzhj 454 7 randomization randomization NN cord-005646-xhx9pzhj 454 8 exclusion exclusion NN cord-005646-xhx9pzhj 454 9 criteria criterion NNS cord-005646-xhx9pzhj 454 10 even even RB cord-005646-xhx9pzhj 454 11 if if IN cord-005646-xhx9pzhj 454 12 Stage stage NN cord-005646-xhx9pzhj 454 13 2 2 CD cord-005646-xhx9pzhj 454 14 was be VBD cord-005646-xhx9pzhj 454 15 reached reach VBN cord-005646-xhx9pzhj 454 16 . . . cord-005646-xhx9pzhj 455 1 19 19 CD cord-005646-xhx9pzhj 455 2 patients patient NNS cord-005646-xhx9pzhj 455 3 reached reach VBD cord-005646-xhx9pzhj 455 4 Stage Stage NNP cord-005646-xhx9pzhj 455 5 2 2 CD cord-005646-xhx9pzhj 455 6 . . . cord-005646-xhx9pzhj 456 1 11 11 CD cord-005646-xhx9pzhj 456 2 had have VBD cord-005646-xhx9pzhj 456 3 exclusions exclusion NNS cord-005646-xhx9pzhj 456 4 from from IN cord-005646-xhx9pzhj 456 5 randomization randomization NN cord-005646-xhx9pzhj 456 6 and and CC cord-005646-xhx9pzhj 456 7 all all DT cord-005646-xhx9pzhj 456 8 died die VBD cord-005646-xhx9pzhj 456 9 . . . cord-005646-xhx9pzhj 457 1 Eight eight CD cord-005646-xhx9pzhj 457 2 patients patient NNS cord-005646-xhx9pzhj 457 3 ( ( -LRB- cord-005646-xhx9pzhj 457 4 4 4 CD cord-005646-xhx9pzhj 457 5 survivors survivor NNS cord-005646-xhx9pzhj 457 6 were be VBD cord-005646-xhx9pzhj 457 7 eligible eligible JJ cord-005646-xhx9pzhj 457 8 for for IN cord-005646-xhx9pzhj 457 9 randomization randomization NN cord-005646-xhx9pzhj 457 10 ; ; : cord-005646-xhx9pzhj 457 11 consent consent NN cord-005646-xhx9pzhj 457 12 was be VBD cord-005646-xhx9pzhj 457 13 obtained obtain VBN cord-005646-xhx9pzhj 457 14 in in IN cord-005646-xhx9pzhj 457 15 no no DT cord-005646-xhx9pzhj 457 16 case case NN cord-005646-xhx9pzhj 457 17 . . . cord-005646-xhx9pzhj 458 1 Two two CD cord-005646-xhx9pzhj 458 2 patients patient NNS cord-005646-xhx9pzhj 458 3 received receive VBD cord-005646-xhx9pzhj 458 4 ECMO ECMO NNP cord-005646-xhx9pzhj 458 5 . . . cord-005646-xhx9pzhj 459 1 Overall overall JJ cord-005646-xhx9pzhj 459 2 survival survival NN cord-005646-xhx9pzhj 459 3 is be VBZ cord-005646-xhx9pzhj 459 4 60 60 CD cord-005646-xhx9pzhj 459 5 % % NN cord-005646-xhx9pzhj 459 6 ( ( -LRB- cord-005646-xhx9pzhj 459 7 51/85 51/85 CD cord-005646-xhx9pzhj 459 8 ) ) -RRB- cord-005646-xhx9pzhj 459 9 . . . cord-005646-xhx9pzhj 460 1 In in IN cord-005646-xhx9pzhj 460 2 patients patient NNS cord-005646-xhx9pzhj 460 3 without without IN cord-005646-xhx9pzhj 460 4 randomization randomization NN cord-005646-xhx9pzhj 460 5 exclusions exclusion NNS cord-005646-xhx9pzhj 460 6 , , , cord-005646-xhx9pzhj 460 7 survival survival NN cord-005646-xhx9pzhj 460 8 is be VBZ cord-005646-xhx9pzhj 460 9 77 77 CD cord-005646-xhx9pzhj 460 10 % % NN cord-005646-xhx9pzhj 460 11 ( ( -LRB- cord-005646-xhx9pzhj 460 12 34/44 34/44 CD cord-005646-xhx9pzhj 460 13 ) ) -RRB- cord-005646-xhx9pzhj 460 14 . . . cord-005646-xhx9pzhj 461 1 Morbidity morbidity NN cord-005646-xhx9pzhj 461 2 m m CD cord-005646-xhx9pzhj 461 3 survivors survivor NNS cord-005646-xhx9pzhj 461 4 ( ( -LRB- cord-005646-xhx9pzhj 461 5 discharge discharge NN cord-005646-xhx9pzhj 461 6 -admission -admission NN cord-005646-xhx9pzhj 461 7 POPC POPC NNP cord-005646-xhx9pzhj 461 8 or or CC cord-005646-xhx9pzhj 461 9 PCPC PCPC NNP cord-005646-xhx9pzhj 461 10 score score NN cord-005646-xhx9pzhj 462 1 > > XX cord-005646-xhx9pzhj 463 1 _ _ NNP cord-005646-xhx9pzhj 463 2 2 2 CD cord-005646-xhx9pzhj 463 3 ) ) -RRB- cord-005646-xhx9pzhj 463 4 was be VBD cord-005646-xhx9pzhj 463 5 seen see VBN cord-005646-xhx9pzhj 463 6 in in IN cord-005646-xhx9pzhj 463 7 none none NN cord-005646-xhx9pzhj 463 8 of of IN cord-005646-xhx9pzhj 463 9 the the DT cord-005646-xhx9pzhj 463 10 4 4 CD cord-005646-xhx9pzhj 463 11 Stage Stage NNP cord-005646-xhx9pzhj 463 12 2 2 CD cord-005646-xhx9pzhj 463 13 surviviors survivior NNS cord-005646-xhx9pzhj 463 14 and and CC cord-005646-xhx9pzhj 463 15 15 15 CD cord-005646-xhx9pzhj 463 16 % % NN cord-005646-xhx9pzhj 463 17 ( ( -LRB- cord-005646-xhx9pzhj 463 18 7/41 7/41 CD cord-005646-xhx9pzhj 463 19 ) ) -RRB- cord-005646-xhx9pzhj 463 20 of of IN cord-005646-xhx9pzhj 463 21 those those DT cord-005646-xhx9pzhj 463 22 who who WP cord-005646-xhx9pzhj 463 23 reached reach VBD cord-005646-xhx9pzhj 463 24 only only RB cord-005646-xhx9pzhj 463 25 Stage stage NN cord-005646-xhx9pzhj 463 26 ! ! . cord-005646-xhx9pzhj 463 27 . . . cord-005646-xhx9pzhj 464 1 Conclusion conclusion NN cord-005646-xhx9pzhj 464 2 : : : cord-005646-xhx9pzhj 465 1 The the DT cord-005646-xhx9pzhj 465 2 RCT RCT NNP cord-005646-xhx9pzhj 465 3 requires require VBZ cord-005646-xhx9pzhj 465 4 completion completion NN cord-005646-xhx9pzhj 465 5 . . . cord-005646-xhx9pzhj 466 1 The the DT cord-005646-xhx9pzhj 466 2 records record NNS cord-005646-xhx9pzhj 466 3 of of IN cord-005646-xhx9pzhj 466 4 hospital hospital NN cord-005646-xhx9pzhj 466 5 in in IN cord-005646-xhx9pzhj 466 6 - - HYPH cord-005646-xhx9pzhj 466 7 patients patient NNS cord-005646-xhx9pzhj 466 8 at at IN cord-005646-xhx9pzhj 466 9 King King NNP cord-005646-xhx9pzhj 466 10 Faisal Faisal NNP cord-005646-xhx9pzhj 466 11 Specialist Specialist NNP cord-005646-xhx9pzhj 466 12 Hospital Hospital NNP cord-005646-xhx9pzhj 466 13 and and CC cord-005646-xhx9pzhj 466 14 Research Research NNP cord-005646-xhx9pzhj 466 15 Center Center NNP cord-005646-xhx9pzhj 466 16 who who WP cord-005646-xhx9pzhj 466 17 received receive VBD cord-005646-xhx9pzhj 466 18 external external JJ cord-005646-xhx9pzhj 466 19 cardiac cardiac NN cord-005646-xhx9pzhj 466 20 massage massage NN cord-005646-xhx9pzhj 466 21 as as IN cord-005646-xhx9pzhj 466 22 part part NN cord-005646-xhx9pzhj 466 23 of of IN cord-005646-xhx9pzhj 466 24 their -PRON- PRP$ cord-005646-xhx9pzhj 466 25 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 466 26 resuscitation resuscitation NN cord-005646-xhx9pzhj 466 27 were be VBD cord-005646-xhx9pzhj 466 28 reviewed review VBN cord-005646-xhx9pzhj 466 29 . . . cord-005646-xhx9pzhj 467 1 Success success NN cord-005646-xhx9pzhj 467 2 of of IN cord-005646-xhx9pzhj 467 3 resuscitation resuscitation NN cord-005646-xhx9pzhj 467 4 was be VBD cord-005646-xhx9pzhj 467 5 analyzed analyze VBN cord-005646-xhx9pzhj 467 6 as as IN cord-005646-xhx9pzhj 467 7 ( ( -LRB- cord-005646-xhx9pzhj 467 8 1 1 CD cord-005646-xhx9pzhj 467 9 ) ) -RRB- cord-005646-xhx9pzhj 467 10 short short JJ cord-005646-xhx9pzhj 467 11 term term NN cord-005646-xhx9pzhj 467 12 ( ( -LRB- cord-005646-xhx9pzhj 467 13 restoration restoration NN cord-005646-xhx9pzhj 467 14 of of IN cord-005646-xhx9pzhj 467 15 spontaneous spontaneous JJ cord-005646-xhx9pzhj 467 16 circulation circulation NN cord-005646-xhx9pzhj 467 17 ) ) -RRB- cord-005646-xhx9pzhj 467 18 , , , cord-005646-xhx9pzhj 467 19 and and CC cord-005646-xhx9pzhj 467 20 ( ( -LRB- cord-005646-xhx9pzhj 467 21 2 2 LS cord-005646-xhx9pzhj 467 22 ) ) -RRB- cord-005646-xhx9pzhj 467 23 long long JJ cord-005646-xhx9pzhj 467 24 term term NN cord-005646-xhx9pzhj 467 25 ( ( -LRB- cord-005646-xhx9pzhj 467 26 discharge discharge NN cord-005646-xhx9pzhj 467 27 from from IN cord-005646-xhx9pzhj 467 28 hospital hospital NN cord-005646-xhx9pzhj 467 29 ) ) -RRB- cord-005646-xhx9pzhj 467 30 . . . cord-005646-xhx9pzhj 468 1 Of of IN cord-005646-xhx9pzhj 468 2 234 234 CD cord-005646-xhx9pzhj 468 3 such such JJ cord-005646-xhx9pzhj 468 4 patients patient NNS cord-005646-xhx9pzhj 468 5 , , , cord-005646-xhx9pzhj 468 6 171 171 CD cord-005646-xhx9pzhj 468 7 ( ( -LRB- cord-005646-xhx9pzhj 468 8 73.1 73.1 CD cord-005646-xhx9pzhj 468 9 % % NN cord-005646-xhx9pzhj 468 10 ) ) -RRB- cord-005646-xhx9pzhj 468 11 survived survive VBD cord-005646-xhx9pzhj 468 12 the the DT cord-005646-xhx9pzhj 468 13 initial initial JJ cord-005646-xhx9pzhj 468 14 resuscitation resuscitation NN cord-005646-xhx9pzhj 468 15 , , , cord-005646-xhx9pzhj 468 16 and and CC cord-005646-xhx9pzhj 468 17 66 66 CD cord-005646-xhx9pzhj 468 18 ( ( -LRB- cord-005646-xhx9pzhj 468 19 28.2 28.2 CD cord-005646-xhx9pzhj 468 20 % % NN cord-005646-xhx9pzhj 468 21 ) ) -RRB- cord-005646-xhx9pzhj 468 22 were be VBD cord-005646-xhx9pzhj 468 23 discharged discharge VBN cord-005646-xhx9pzhj 468 24 . . . cord-005646-xhx9pzhj 469 1 Success success NN cord-005646-xhx9pzhj 469 2 of of IN cord-005646-xhx9pzhj 469 3 outcome outcome NN cord-005646-xhx9pzhj 469 4 was be VBD cord-005646-xhx9pzhj 469 5 not not RB cord-005646-xhx9pzhj 469 6 related relate VBN cord-005646-xhx9pzhj 469 7 to to IN cord-005646-xhx9pzhj 469 8 age age NN cord-005646-xhx9pzhj 469 9 , , , cord-005646-xhx9pzhj 469 10 location location NN cord-005646-xhx9pzhj 469 11 of of IN cord-005646-xhx9pzhj 469 12 patient patient NN cord-005646-xhx9pzhj 469 13 , , , cord-005646-xhx9pzhj 469 14 time time NN cord-005646-xhx9pzhj 469 15 of of IN cord-005646-xhx9pzhj 469 16 day day NN cord-005646-xhx9pzhj 469 17 , , , cord-005646-xhx9pzhj 469 18 or or CC cord-005646-xhx9pzhj 469 19 rhythm rhythm NN cord-005646-xhx9pzhj 469 20 at at IN cord-005646-xhx9pzhj 469 21 arrest arrest NN cord-005646-xhx9pzhj 469 22 , , , cord-005646-xhx9pzhj 469 23 including include VBG cord-005646-xhx9pzhj 469 24 asystole asystole NN cord-005646-xhx9pzhj 469 25 . . . cord-005646-xhx9pzhj 470 1 Longer long JJR cord-005646-xhx9pzhj 470 2 resuscitation resuscitation NN cord-005646-xhx9pzhj 470 3 time time NN cord-005646-xhx9pzhj 470 4 was be VBD cord-005646-xhx9pzhj 470 5 associated associate VBN cord-005646-xhx9pzhj 470 6 with with IN cord-005646-xhx9pzhj 470 7 less less JJR cord-005646-xhx9pzhj 470 8 chance chance NN cord-005646-xhx9pzhj 470 9 of of IN cord-005646-xhx9pzhj 470 10 restoration restoration NN cord-005646-xhx9pzhj 470 11 of of IN cord-005646-xhx9pzhj 470 12 spontaneous spontaneous JJ cord-005646-xhx9pzhj 470 13 circulation circulation NN cord-005646-xhx9pzhj 470 14 ( ( -LRB- cord-005646-xhx9pzhj 470 15 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 470 16 ) ) -RRB- cord-005646-xhx9pzhj 470 17 , , , cord-005646-xhx9pzhj 470 18 but but CC cord-005646-xhx9pzhj 470 19 not not RB cord-005646-xhx9pzhj 470 20 associated associate VBN cord-005646-xhx9pzhj 470 21 with with IN cord-005646-xhx9pzhj 470 22 Hospital hospital NN cord-005646-xhx9pzhj 470 23 discharge discharge NN cord-005646-xhx9pzhj 470 24 rate rate NN cord-005646-xhx9pzhj 470 25 . . . cord-005646-xhx9pzhj 471 1 Results result NNS cord-005646-xhx9pzhj 471 2 for for IN cord-005646-xhx9pzhj 471 3 patients patient NNS cord-005646-xhx9pzhj 471 4 with with IN cord-005646-xhx9pzhj 471 5 congenital congenital JJ cord-005646-xhx9pzhj 471 6 heart heart NN cord-005646-xhx9pzhj 471 7 disease disease NN cord-005646-xhx9pzhj 471 8 were be VBD cord-005646-xhx9pzhj 471 9 similar similar JJ cord-005646-xhx9pzhj 471 10 to to IN cord-005646-xhx9pzhj 471 11 those those DT cord-005646-xhx9pzhj 471 12 with with IN cord-005646-xhx9pzhj 471 13 other other JJ cord-005646-xhx9pzhj 471 14 medical medical JJ cord-005646-xhx9pzhj 471 15 or or CC cord-005646-xhx9pzhj 471 16 surgical surgical JJ cord-005646-xhx9pzhj 471 17 conditions condition NNS cord-005646-xhx9pzhj 471 18 . . . cord-005646-xhx9pzhj 472 1 In in IN cord-005646-xhx9pzhj 472 2 this this DT cord-005646-xhx9pzhj 472 3 series series NN cord-005646-xhx9pzhj 472 4 , , , cord-005646-xhx9pzhj 472 5 36.7 36.7 CD cord-005646-xhx9pzhj 472 6 % % NN cord-005646-xhx9pzhj 472 7 of of IN cord-005646-xhx9pzhj 472 8 ward ward NN cord-005646-xhx9pzhj 472 9 in in IN cord-005646-xhx9pzhj 472 10 - - HYPH cord-005646-xhx9pzhj 472 11 patients patient NNS cord-005646-xhx9pzhj 472 12 survived survive VBD cord-005646-xhx9pzhj 472 13 to to TO cord-005646-xhx9pzhj 472 14 discharge discharge VB cord-005646-xhx9pzhj 472 15 , , , cord-005646-xhx9pzhj 472 16 compared compare VBN cord-005646-xhx9pzhj 472 17 to to IN cord-005646-xhx9pzhj 472 18 two two CD cord-005646-xhx9pzhj 472 19 5"*;'~r 5"*;'~r CD cord-005646-xhx9pzhj 472 20 ~r;~'9 ~r;~'9 XX cord-005646-xhx9pzhj 472 21 , , , cord-005646-xhx9pzhj 472 22 . . . cord-005646-xhx9pzhj 472 23 , , , cord-005646-xhx9pzhj 472 24 . . . cord-005646-xhx9pzhj 473 1 ' ' '' cord-005646-xhx9pzhj 473 2 her -PRON- PRP cord-005646-xhx9pzhj 473 3 , , , cord-005646-xhx9pzhj 473 4 , , , cord-005646-xhx9pzhj 473 5 the the DT cord-005646-xhx9pzhj 473 6 r r NN cord-005646-xhx9pzhj 473 7 - - HYPH cord-005646-xhx9pzhj 473 8 e e NN cord-005646-xhx9pzhj 473 9 ~ ~ CD cord-005646-xhx9pzhj 473 10 ult~ ult~ NNP cord-005646-xhx9pzhj 473 11 were be VBD cord-005646-xhx9pzhj 473 12 0c/ 0c/ CD cord-005646-xhx9pzhj 473 13 " " '' cord-005646-xhx9pzhj 473 14 ' ' '' cord-005646-xhx9pzhj 474 1 ~d ~d NNP cord-005646-xhx9pzhj 474 2 ~ ~ NFP cord-005646-xhx9pzhj 474 3 , , , cord-005646-xhx9pzhj 474 4 ~ ~ NFP cord-005646-xhx9pzhj 474 5 , , , cord-005646-xhx9pzhj 474 6 ° ° NNP cord-005646-xhx9pzhj 474 7 ( ( -LRB- cord-005646-xhx9pzhj 474 8 . . . cord-005646-xhx9pzhj 475 1 Overall overall RB cord-005646-xhx9pzhj 475 2 , , , cord-005646-xhx9pzhj 475 3 39 39 CD cord-005646-xhx9pzhj 475 4 7 7 CD cord-005646-xhx9pzhj 475 5 % % NN cord-005646-xhx9pzhj 475 6 of of IN cord-005646-xhx9pzhj 475 7 patients patient NNS cord-005646-xhx9pzhj 475 8 who who WP cord-005646-xhx9pzhj 475 9 survived survive VBD cord-005646-xhx9pzhj 475 10 the the DT cord-005646-xhx9pzhj 475 11 initial initial JJ cord-005646-xhx9pzhj 475 12 resuscitation resuscitation NN cord-005646-xhx9pzhj 475 13 were be VBD cord-005646-xhx9pzhj 475 14 discharged discharge VBN cord-005646-xhx9pzhj 475 15 from from IN cord-005646-xhx9pzhj 475 16 hospital hospital NN cord-005646-xhx9pzhj 475 17 . . . cord-005646-xhx9pzhj 476 1 Where where WRB cord-005646-xhx9pzhj 476 2 resuscitation resuscitation NN cord-005646-xhx9pzhj 476 3 continued continue VBD cord-005646-xhx9pzhj 476 4 for for IN cord-005646-xhx9pzhj 476 5 more more JJR cord-005646-xhx9pzhj 476 6 than than IN cord-005646-xhx9pzhj 476 7 30 30 CD cord-005646-xhx9pzhj 476 8 minutes minute NNS cord-005646-xhx9pzhj 476 9 , , , cord-005646-xhx9pzhj 476 10 18.9 18.9 CD cord-005646-xhx9pzhj 476 11 % % NN cord-005646-xhx9pzhj 476 12 of of IN cord-005646-xhx9pzhj 476 13 patients patient NNS cord-005646-xhx9pzhj 476 14 had have VBD cord-005646-xhx9pzhj 476 15 tong tong NNP cord-005646-xhx9pzhj 476 16 term term NN cord-005646-xhx9pzhj 476 17 survival survival NN cord-005646-xhx9pzhj 476 18 . . . cord-005646-xhx9pzhj 477 1 Outcome outcome NN cord-005646-xhx9pzhj 477 2 from from IN cord-005646-xhx9pzhj 477 3 asystole asystole NN cord-005646-xhx9pzhj 477 4 was be VBD cord-005646-xhx9pzhj 477 5 no no RB cord-005646-xhx9pzhj 477 6 worse bad JJR cord-005646-xhx9pzhj 477 7 than than IN cord-005646-xhx9pzhj 477 8 for for IN cord-005646-xhx9pzhj 477 9 other other JJ cord-005646-xhx9pzhj 477 10 cardiac cardiac JJ cord-005646-xhx9pzhj 477 11 rhythms rhythm NNS cord-005646-xhx9pzhj 477 12 , , , cord-005646-xhx9pzhj 477 13 We -PRON- PRP cord-005646-xhx9pzhj 477 14 believe believe VBP cord-005646-xhx9pzhj 477 15 that that IN cord-005646-xhx9pzhj 477 16 previous previous JJ cord-005646-xhx9pzhj 477 17 reports report NNS cord-005646-xhx9pzhj 477 18 of of IN cord-005646-xhx9pzhj 477 19 poor poor JJ cord-005646-xhx9pzhj 477 20 outcome outcome NN cord-005646-xhx9pzhj 477 21 from from IN cord-005646-xhx9pzhj 477 22 asystole asystole NN cord-005646-xhx9pzhj 477 23 in in IN cord-005646-xhx9pzhj 477 24 pediatric pediatric JJ cord-005646-xhx9pzhj 477 25 cardiac cardiac JJ cord-005646-xhx9pzhj 477 26 arrest arrest NN cord-005646-xhx9pzhj 477 27 should should MD cord-005646-xhx9pzhj 477 28 noI noi JJ cord-005646-xhx9pzhj 477 29 influence influence NN cord-005646-xhx9pzhj 477 30 decisions decision NNS cord-005646-xhx9pzhj 477 31 to to TO cord-005646-xhx9pzhj 477 32 stop stop VB cord-005646-xhx9pzhj 477 33 resuscitation resuscitation NN cord-005646-xhx9pzhj 477 34 for for IN cord-005646-xhx9pzhj 477 35 pediatric pediatric JJ cord-005646-xhx9pzhj 477 36 in in NN cord-005646-xhx9pzhj 477 37 - - HYPH cord-005646-xhx9pzhj 477 38 patients patient NNS cord-005646-xhx9pzhj 477 39 prematurely prematurely RB cord-005646-xhx9pzhj 477 40 . . . cord-005646-xhx9pzhj 478 1 Successful successful JJ cord-005646-xhx9pzhj 478 2 restoration restoration NN cord-005646-xhx9pzhj 478 3 of of IN cord-005646-xhx9pzhj 478 4 spontaneous spontaneous JJ cord-005646-xhx9pzhj 478 5 circulation circulation NN cord-005646-xhx9pzhj 478 6 with with IN cord-005646-xhx9pzhj 478 7 long long JJ cord-005646-xhx9pzhj 478 8 term term NN cord-005646-xhx9pzhj 478 9 survival survival NN cord-005646-xhx9pzhj 478 10 can can MD cord-005646-xhx9pzhj 478 11 be be VB cord-005646-xhx9pzhj 478 12 achieved achieve VBN cord-005646-xhx9pzhj 478 13 after after IN cord-005646-xhx9pzhj 478 14 prolonged prolong VBN cord-005646-xhx9pzhj 478 15 resuscitation resuscitation NN cord-005646-xhx9pzhj 478 16 . . . cord-005646-xhx9pzhj 479 1 Abdelmoniem~ Abdelmoniem~ NFP cord-005646-xhx9pzhj 480 1 Lindsey Lindsey NNP cord-005646-xhx9pzhj 480 2 Jahusou~,Mariano Jahusou~,Mariano NNP cord-005646-xhx9pzhj 480 3 Fiallos Fiallos NNP cord-005646-xhx9pzhj 480 4 , , , cord-005646-xhx9pzhj 480 5 University University NNP cord-005646-xhx9pzhj 480 6 of of IN cord-005646-xhx9pzhj 480 7 Florida Florida NNP cord-005646-xhx9pzhj 480 8 , , , cord-005646-xhx9pzhj 480 9 820 820 CD cord-005646-xhx9pzhj 480 10 Prudential Prudential NNP cord-005646-xhx9pzhj 480 11 Drive Drive NNP cord-005646-xhx9pzhj 480 12 , , , cord-005646-xhx9pzhj 480 13 Suite Suite NNP cord-005646-xhx9pzhj 480 14 203 203 CD cord-005646-xhx9pzhj 480 15 Jacksonville Jacksonville NNP cord-005646-xhx9pzhj 480 16 , , , cord-005646-xhx9pzhj 480 17 Florida Florida NNP cord-005646-xhx9pzhj 480 18 32207 32207 CD cord-005646-xhx9pzhj 480 19 USA USA NNP cord-005646-xhx9pzhj 480 20 Central central JJ cord-005646-xhx9pzhj 480 21 acidosis acidosis NN cord-005646-xhx9pzhj 480 22 is be VBZ cord-005646-xhx9pzhj 480 23 well well RB cord-005646-xhx9pzhj 480 24 recognized recognize VBN cord-005646-xhx9pzhj 480 25 as as IN cord-005646-xhx9pzhj 480 26 a a DT cord-005646-xhx9pzhj 480 27 marker marker NN cord-005646-xhx9pzhj 480 28 of of IN cord-005646-xhx9pzhj 480 29 inadequate inadequate JJ cord-005646-xhx9pzhj 480 30 tissue tissue NN cord-005646-xhx9pzhj 480 31 perfusiou perfusiou NN cord-005646-xhx9pzhj 480 32 , , , cord-005646-xhx9pzhj 480 33 and and CC cord-005646-xhx9pzhj 480 34 ventilation ventilation NN cord-005646-xhx9pzhj 480 35 . . . cord-005646-xhx9pzhj 481 1 However however RB cord-005646-xhx9pzhj 481 2 , , , cord-005646-xhx9pzhj 481 3 obtaining obtain VBG cord-005646-xhx9pzhj 481 4 central central JJ cord-005646-xhx9pzhj 481 5 venous venous JJ cord-005646-xhx9pzhj 481 6 blcod blcod NNP cord-005646-xhx9pzhj 481 7 is be VBZ cord-005646-xhx9pzhj 481 8 difficult difficult JJ cord-005646-xhx9pzhj 481 9 and and CC cord-005646-xhx9pzhj 481 10 fraught fraught JJ cord-005646-xhx9pzhj 481 11 with with IN cord-005646-xhx9pzhj 481 12 complications complication NNS cord-005646-xhx9pzhj 481 13 in in IN cord-005646-xhx9pzhj 481 14 the the DT cord-005646-xhx9pzhj 481 15 child child NN cord-005646-xhx9pzhj 481 16 undergoing undergo VBG cord-005646-xhx9pzhj 481 17 cardiopuimonary cardiopuimonary JJ cord-005646-xhx9pzhj 481 18 resuscitation resuscitation NN cord-005646-xhx9pzhj 481 19 . . . cord-005646-xhx9pzhj 482 1 Intraosseous intraosseous JJ cord-005646-xhx9pzhj 482 2 blood blood NN cord-005646-xhx9pzhj 482 3 may may MD cord-005646-xhx9pzhj 482 4 be be VB cord-005646-xhx9pzhj 482 5 used use VBN cord-005646-xhx9pzhj 482 6 instead instead RB cord-005646-xhx9pzhj 482 7 of of IN cord-005646-xhx9pzhj 482 8 central central JJ cord-005646-xhx9pzhj 482 9 venous venous JJ cord-005646-xhx9pzhj 482 10 blood blood NN cord-005646-xhx9pzhj 482 11 to to TO cord-005646-xhx9pzhj 482 12 judge judge VB cord-005646-xhx9pzhj 482 13 pH pH NNP cord-005646-xhx9pzhj 482 14 and and CC cord-005646-xhx9pzhj 482 15 pCOz pcoz XX cord-005646-xhx9pzhj 482 16 during during IN cord-005646-xhx9pzhj 482 17 short short JJ cord-005646-xhx9pzhj 482 18 durations duration NNS cord-005646-xhx9pzhj 482 19 of of IN cord-005646-xhx9pzhj 482 20 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 482 21 resuscitation resuscitation NN cord-005646-xhx9pzhj 482 22 and and CC cord-005646-xhx9pzhj 482 23 during during IN cord-005646-xhx9pzhj 482 24 hemorrhagic hemorrhagic JJ cord-005646-xhx9pzhj 482 25 shock shock NN cord-005646-xhx9pzhj 482 26 . . . cord-005646-xhx9pzhj 483 1 The the DT cord-005646-xhx9pzhj 483 2 purpose purpose NN cord-005646-xhx9pzhj 483 3 of of IN cord-005646-xhx9pzhj 483 4 this this DT cord-005646-xhx9pzhj 483 5 study study NN cord-005646-xhx9pzhj 483 6 is be VBZ cord-005646-xhx9pzhj 483 7 to to TO cord-005646-xhx9pzhj 483 8 compare compare VB cord-005646-xhx9pzhj 483 9 the the DT cord-005646-xhx9pzhj 483 10 pH ph NN cord-005646-xhx9pzhj 483 11 and and CC cord-005646-xhx9pzhj 483 12 pCOz pcoz NN cord-005646-xhx9pzhj 483 13 status status NN cord-005646-xhx9pzhj 483 14 of of IN cord-005646-xhx9pzhj 483 15 intraosseous intraosseous JJ cord-005646-xhx9pzhj 483 16 and and CC cord-005646-xhx9pzhj 483 17 central central JJ cord-005646-xhx9pzhj 483 18 venous venous NN cord-005646-xhx9pzhj 483 19 during during IN cord-005646-xhx9pzhj 483 20 prolonged prolonged JJ cord-005646-xhx9pzhj 483 21 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 483 22 resuscitation resuscitation NN cord-005646-xhx9pzhj 483 23 after after IN cord-005646-xhx9pzhj 483 24 fluid fluid NN cord-005646-xhx9pzhj 483 25 and and CC cord-005646-xhx9pzhj 483 26 drug drug NN cord-005646-xhx9pzhj 483 27 infusion infusion NN cord-005646-xhx9pzhj 483 28 . . . cord-005646-xhx9pzhj 484 1 We -PRON- PRP cord-005646-xhx9pzhj 484 2 hypotbesized hypotbesize VBD cord-005646-xhx9pzhj 484 3 that that IN cord-005646-xhx9pzhj 484 4 there there EX cord-005646-xhx9pzhj 484 5 would would MD cord-005646-xhx9pzhj 484 6 be be VB cord-005646-xhx9pzhj 484 7 no no DT cord-005646-xhx9pzhj 484 8 difference difference NN cord-005646-xhx9pzhj 484 9 in in IN cord-005646-xhx9pzhj 484 10 pH ph NN cord-005646-xhx9pzhj 484 11 and and CC cord-005646-xhx9pzhj 485 1 pCO2 pco2 IN cord-005646-xhx9pzhj 485 2 values value NNS cord-005646-xhx9pzhj 485 3 of of IN cord-005646-xhx9pzhj 485 4 simultanecusly simultanecusly NN cord-005646-xhx9pzhj 485 5 obtained obtain VBN cord-005646-xhx9pzhj 485 6 intraosseous intraosseous JJ cord-005646-xhx9pzhj 485 7 and and CC cord-005646-xhx9pzhj 485 8 central central JJ cord-005646-xhx9pzhj 485 9 venous venous JJ cord-005646-xhx9pzhj 485 10 blood blood NN cord-005646-xhx9pzhj 485 11 samples sample NNS cord-005646-xhx9pzhj 485 12 . . . cord-005646-xhx9pzhj 486 1 Eighteen eighteen CD cord-005646-xhx9pzhj 486 2 ( ( -LRB- cord-005646-xhx9pzhj 486 3 18 18 CD cord-005646-xhx9pzhj 486 4 ) ) -RRB- cord-005646-xhx9pzhj 486 5 INTRODUCTION introduction NN cord-005646-xhx9pzhj 486 6 : : : cord-005646-xhx9pzhj 487 1 Cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 487 2 arrest arrest NN cord-005646-xhx9pzhj 487 3 ( ( -LRB- cord-005646-xhx9pzhj 487 4 CPA cpa NN cord-005646-xhx9pzhj 487 5 ) ) -RRB- cord-005646-xhx9pzhj 487 6 in in IN cord-005646-xhx9pzhj 487 7 children child NNS cord-005646-xhx9pzhj 487 8 is be VBZ cord-005646-xhx9pzhj 487 9 usually usually RB cord-005646-xhx9pzhj 487 10 preceded precede VBN cord-005646-xhx9pzhj 487 11 by by IN cord-005646-xhx9pzhj 487 12 a a DT cord-005646-xhx9pzhj 487 13 deterioration deterioration NN cord-005646-xhx9pzhj 487 14 of of IN cord-005646-xhx9pzhj 487 15 cardiac cardiac JJ cord-005646-xhx9pzhj 487 16 or or CC cord-005646-xhx9pzhj 487 17 respiratory respiratory JJ cord-005646-xhx9pzhj 487 18 function function NN cord-005646-xhx9pzhj 487 19 due due IN cord-005646-xhx9pzhj 487 20 to to IN cord-005646-xhx9pzhj 487 21 sepsis sepsis NN cord-005646-xhx9pzhj 487 22 , , , cord-005646-xhx9pzhj 487 23 dehydration dehydration NN cord-005646-xhx9pzhj 487 24 and and CC cord-005646-xhx9pzhj 487 25 hypovolemia hypovolemia NN cord-005646-xhx9pzhj 487 26 . . . cord-005646-xhx9pzhj 488 1 Early early JJ cord-005646-xhx9pzhj 488 2 recognition recognition NN cord-005646-xhx9pzhj 488 3 of of IN cord-005646-xhx9pzhj 488 4 clinical clinical JJ cord-005646-xhx9pzhj 488 5 and and CC cord-005646-xhx9pzhj 488 6 laboratory laboratory NN cord-005646-xhx9pzhj 488 7 signs sign NNS cord-005646-xhx9pzhj 488 8 followed follow VBN cord-005646-xhx9pzhj 488 9 by by IN cord-005646-xhx9pzhj 488 10 immediate immediate JJ cord-005646-xhx9pzhj 488 11 intervention intervention NN cord-005646-xhx9pzhj 488 12 are be VBP cord-005646-xhx9pzhj 488 13 essential essential JJ cord-005646-xhx9pzhj 488 14 for for IN cord-005646-xhx9pzhj 488 15 prevention prevention NN cord-005646-xhx9pzhj 488 16 of of IN cord-005646-xhx9pzhj 488 17 CPA CPA NNP cord-005646-xhx9pzhj 488 18 . . . cord-005646-xhx9pzhj 489 1 The the DT cord-005646-xhx9pzhj 489 2 purpose purpose NN cord-005646-xhx9pzhj 489 3 of of IN cord-005646-xhx9pzhj 489 4 the the DT cord-005646-xhx9pzhj 489 5 present present JJ cord-005646-xhx9pzhj 489 6 study study NN cord-005646-xhx9pzhj 489 7 was be VBD cord-005646-xhx9pzhj 489 8 to to TO cord-005646-xhx9pzhj 489 9 identify identify VB cord-005646-xhx9pzhj 489 10 factors factor NNS cord-005646-xhx9pzhj 489 11 which which WDT cord-005646-xhx9pzhj 489 12 contributed contribute VBD cord-005646-xhx9pzhj 489 13 to to IN cord-005646-xhx9pzhj 489 14 high high JJ cord-005646-xhx9pzhj 489 15 rates rate NNS cord-005646-xhx9pzhj 489 16 of of IN cord-005646-xhx9pzhj 489 17 mortality mortality NN cord-005646-xhx9pzhj 489 18 from from IN cord-005646-xhx9pzhj 489 19 CPA cpa NN cord-005646-xhx9pzhj 489 20 in in IN cord-005646-xhx9pzhj 489 21 patients patient NNS cord-005646-xhx9pzhj 489 22 admitted admit VBN cord-005646-xhx9pzhj 489 23 to to IN cord-005646-xhx9pzhj 489 24 a a DT cord-005646-xhx9pzhj 489 25 Paediatric Paediatric NNP cord-005646-xhx9pzhj 489 26 Intensive Intensive NNP cord-005646-xhx9pzhj 489 27 Care Care NNP cord-005646-xhx9pzhj 489 28 Unit Unit NNP cord-005646-xhx9pzhj 489 29 ( ( -LRB- cord-005646-xhx9pzhj 489 30 P1CU P1CU NNP cord-005646-xhx9pzhj 489 31 ) ) -RRB- cord-005646-xhx9pzhj 489 32 . . . cord-005646-xhx9pzhj 490 1 METHODS methods NN cord-005646-xhx9pzhj 490 2 : : : cord-005646-xhx9pzhj 491 1 A a DT cord-005646-xhx9pzhj 491 2 prospective prospective JJ cord-005646-xhx9pzhj 491 3 study study NN cord-005646-xhx9pzhj 491 4 was be VBD cord-005646-xhx9pzhj 491 5 done do VBN cord-005646-xhx9pzhj 491 6 of of IN cord-005646-xhx9pzhj 491 7 all all DT cord-005646-xhx9pzhj 491 8 non non JJ cord-005646-xhx9pzhj 491 9 - - JJ cord-005646-xhx9pzhj 491 10 surgical surgical JJ cord-005646-xhx9pzhj 491 11 patients patient NNS cord-005646-xhx9pzhj 491 12 with with IN cord-005646-xhx9pzhj 491 13 CPA cpa NN cord-005646-xhx9pzhj 491 14 who who WP cord-005646-xhx9pzhj 491 15 were be VBD cord-005646-xhx9pzhj 491 16 admitted admit VBN cord-005646-xhx9pzhj 491 17 to to IN cord-005646-xhx9pzhj 491 18 the the DT cord-005646-xhx9pzhj 491 19 PICU PICU NNP cord-005646-xhx9pzhj 491 20 , , , cord-005646-xhx9pzhj 491 21 Hospital Hospital NNP cord-005646-xhx9pzhj 491 22 Baca Baca NNP cord-005646-xhx9pzhj 491 23 Ortiz Ortiz NNP cord-005646-xhx9pzhj 491 24 , , , cord-005646-xhx9pzhj 491 25 Quito Quito NNP cord-005646-xhx9pzhj 491 26 Ecuador Ecuador NNP cord-005646-xhx9pzhj 491 27 from from IN cord-005646-xhx9pzhj 491 28 January January NNP cord-005646-xhx9pzhj 491 29 to to IN cord-005646-xhx9pzhj 491 30 October October NNP cord-005646-xhx9pzhj 491 31 1995 1995 CD cord-005646-xhx9pzhj 491 32 . . . cord-005646-xhx9pzhj 492 1 Clinical clinical JJ cord-005646-xhx9pzhj 492 2 and and CC cord-005646-xhx9pzhj 492 3 laboratory laboratory NN cord-005646-xhx9pzhj 492 4 variables variable NNS cord-005646-xhx9pzhj 492 5 before before IN cord-005646-xhx9pzhj 492 6 and and CC cord-005646-xhx9pzhj 492 7 after after IN cord-005646-xhx9pzhj 492 8 admission admission NN cord-005646-xhx9pzhj 492 9 to to IN cord-005646-xhx9pzhj 492 10 the the DT cord-005646-xhx9pzhj 492 11 PICU PICU NNP cord-005646-xhx9pzhj 492 12 , , , cord-005646-xhx9pzhj 492 13 time time NN cord-005646-xhx9pzhj 492 14 from from IN cord-005646-xhx9pzhj 492 15 hospital hospital NN cord-005646-xhx9pzhj 492 16 admission admission NN cord-005646-xhx9pzhj 492 17 to to IN cord-005646-xhx9pzhj 492 18 PICU PICU NNP cord-005646-xhx9pzhj 492 19 admission admission NN cord-005646-xhx9pzhj 492 20 and and CC cord-005646-xhx9pzhj 492 21 the the DT cord-005646-xhx9pzhj 492 22 Pediatric Pediatric NNP cord-005646-xhx9pzhj 492 23 Risk Risk NNP cord-005646-xhx9pzhj 492 24 of of IN cord-005646-xhx9pzhj 492 25 Mortality Mortality NNP cord-005646-xhx9pzhj 492 26 score score NN cord-005646-xhx9pzhj 492 27 ( ( -LRB- cord-005646-xhx9pzhj 492 28 PRISM PRISM NNP cord-005646-xhx9pzhj 492 29 ) ) -RRB- cord-005646-xhx9pzhj 492 30 were be VBD cord-005646-xhx9pzhj 492 31 recorded record VBN cord-005646-xhx9pzhj 492 32 on on IN cord-005646-xhx9pzhj 492 33 a a DT cord-005646-xhx9pzhj 492 34 questionnaire questionnaire NN cord-005646-xhx9pzhj 492 35 designed design VBN cord-005646-xhx9pzhj 492 36 specifically specifically RB cord-005646-xhx9pzhj 492 37 for for IN cord-005646-xhx9pzhj 492 38 this this DT cord-005646-xhx9pzhj 492 39 study study NN cord-005646-xhx9pzhj 492 40 . . . cord-005646-xhx9pzhj 493 1 RESULTS result NNS cord-005646-xhx9pzhj 493 2 : : : cord-005646-xhx9pzhj 494 1 Of of IN cord-005646-xhx9pzhj 494 2 the the DT cord-005646-xhx9pzhj 494 3 70 70 CD cord-005646-xhx9pzhj 494 4 non non JJ cord-005646-xhx9pzhj 494 5 - - JJ cord-005646-xhx9pzhj 494 6 surgical surgical JJ cord-005646-xhx9pzhj 494 7 patients patient NNS cord-005646-xhx9pzhj 494 8 admitted admit VBN cord-005646-xhx9pzhj 494 9 to to IN cord-005646-xhx9pzhj 494 10 the the DT cord-005646-xhx9pzhj 494 11 PICU PICU NNP cord-005646-xhx9pzhj 494 12 , , , cord-005646-xhx9pzhj 494 13 14 14 CD cord-005646-xhx9pzhj 494 14 ( ( -LRB- cord-005646-xhx9pzhj 494 15 20 20 CD cord-005646-xhx9pzhj 494 16 % % NN cord-005646-xhx9pzhj 494 17 ) ) -RRB- cord-005646-xhx9pzhj 494 18 were be VBD cord-005646-xhx9pzhj 494 19 admitted admit VBN cord-005646-xhx9pzhj 494 20 after after IN cord-005646-xhx9pzhj 494 21 developing develop VBG cord-005646-xhx9pzhj 494 22 CPA cpa NN cord-005646-xhx9pzhj 494 23 on on IN cord-005646-xhx9pzhj 494 24 the the DT cord-005646-xhx9pzhj 494 25 general general JJ cord-005646-xhx9pzhj 494 26 pediatric pediatric JJ cord-005646-xhx9pzhj 494 27 wards ward NNS cord-005646-xhx9pzhj 494 28 . . . cord-005646-xhx9pzhj 495 1 Mean mean JJ cord-005646-xhx9pzhj 495 2 age age NN cord-005646-xhx9pzhj 495 3 was be VBD cord-005646-xhx9pzhj 495 4 16 16 CD cord-005646-xhx9pzhj 495 5 + + SYM cord-005646-xhx9pzhj 495 6 19.1 19.1 CD cord-005646-xhx9pzhj 495 7 months month NNS cord-005646-xhx9pzhj 495 8 , , , cord-005646-xhx9pzhj 495 9 with with IN cord-005646-xhx9pzhj 495 10 13 13 CD cord-005646-xhx9pzhj 495 11 of of IN cord-005646-xhx9pzhj 495 12 14 14 CD cord-005646-xhx9pzhj 495 13 patients patient NNS cord-005646-xhx9pzhj 495 14 under under IN cord-005646-xhx9pzhj 495 15 20 20 CD cord-005646-xhx9pzhj 495 16 months month NNS cord-005646-xhx9pzhj 495 17 of of IN cord-005646-xhx9pzhj 495 18 age age NN cord-005646-xhx9pzhj 495 19 . . . cord-005646-xhx9pzhj 496 1 Initial initial JJ cord-005646-xhx9pzhj 496 2 diagnoses diagnosis NNS cord-005646-xhx9pzhj 496 3 upon upon IN cord-005646-xhx9pzhj 496 4 PICU PICU NNP cord-005646-xhx9pzhj 496 5 admission admission NN cord-005646-xhx9pzhj 496 6 included include VBD cord-005646-xhx9pzhj 496 7 meningitis meningitis NN cord-005646-xhx9pzhj 496 8 ( ( -LRB- cord-005646-xhx9pzhj 496 9 n=3 n=3 NN cord-005646-xhx9pzhj 496 10 ) ) -RRB- cord-005646-xhx9pzhj 496 11 , , , cord-005646-xhx9pzhj 496 12 respiratory respiratory JJ cord-005646-xhx9pzhj 496 13 failure failure NN cord-005646-xhx9pzhj 496 14 ( ( -LRB- cord-005646-xhx9pzhj 496 15 n=2 n=2 NNS cord-005646-xhx9pzhj 496 16 ) ) -RRB- cord-005646-xhx9pzhj 496 17 , , , cord-005646-xhx9pzhj 496 18 congenital congenital JJ cord-005646-xhx9pzhj 496 19 heart heart NN cord-005646-xhx9pzhj 496 20 disease disease NN cord-005646-xhx9pzhj 496 21 ( ( -LRB- cord-005646-xhx9pzhj 496 22 n=2 n=2 NNS cord-005646-xhx9pzhj 496 23 ) ) -RRB- cord-005646-xhx9pzhj 496 24 , , , cord-005646-xhx9pzhj 496 25 severe severe JJ cord-005646-xhx9pzhj 496 26 neurological neurological JJ cord-005646-xhx9pzhj 496 27 impairment impairment NN cord-005646-xhx9pzhj 496 28 ( ( -LRB- cord-005646-xhx9pzhj 496 29 n=2 n=2 NNS cord-005646-xhx9pzhj 496 30 ) ) -RRB- cord-005646-xhx9pzhj 496 31 , , , cord-005646-xhx9pzhj 496 32 end end VBP cord-005646-xhx9pzhj 496 33 stage stage NN cord-005646-xhx9pzhj 496 34 neoplastic neoplastic JJ cord-005646-xhx9pzhj 496 35 disease disease NN cord-005646-xhx9pzhj 496 36 ( ( -LRB- cord-005646-xhx9pzhj 496 37 n=2 n=2 NNP cord-005646-xhx9pzhj 496 38 ) ) -RRB- cord-005646-xhx9pzhj 496 39 , , , cord-005646-xhx9pzhj 496 40 hypovolaemic hypovolaemic NNP cord-005646-xhx9pzhj 496 41 shock shock NN cord-005646-xhx9pzhj 496 42 ( ( -LRB- cord-005646-xhx9pzhj 496 43 n n NN cord-005646-xhx9pzhj 496 44 = = SYM cord-005646-xhx9pzhj 496 45 l l NN cord-005646-xhx9pzhj 496 46 ) ) -RRB- cord-005646-xhx9pzhj 496 47 , , , cord-005646-xhx9pzhj 496 48 peritonitis peritonitis NN cord-005646-xhx9pzhj 496 49 ( ( -LRB- cord-005646-xhx9pzhj 496 50 n n NN cord-005646-xhx9pzhj 496 51 = = NN cord-005646-xhx9pzhj 496 52 l l NN cord-005646-xhx9pzhj 496 53 ) ) -RRB- cord-005646-xhx9pzhj 496 54 and and CC cord-005646-xhx9pzhj 496 55 sepsis sepsis NN cord-005646-xhx9pzhj 496 56 ( ( -LRB- cord-005646-xhx9pzhj 496 57 n n NN cord-005646-xhx9pzhj 496 58 = = NN cord-005646-xhx9pzhj 496 59 l l NN cord-005646-xhx9pzhj 496 60 ) ) -RRB- cord-005646-xhx9pzhj 496 61 . . . cord-005646-xhx9pzhj 497 1 Mean mean JJ cord-005646-xhx9pzhj 497 2 time time NN cord-005646-xhx9pzhj 497 3 from from IN cord-005646-xhx9pzhj 497 4 hospital hospital NN cord-005646-xhx9pzhj 497 5 admission admission NN cord-005646-xhx9pzhj 497 6 to to IN cord-005646-xhx9pzhj 497 7 P1CU P1CU NNP cord-005646-xhx9pzhj 497 8 admission admission NN cord-005646-xhx9pzhj 497 9 was be VBD cord-005646-xhx9pzhj 497 10 16 16 CD cord-005646-xhx9pzhj 497 11 _ _ NN cord-005646-xhx9pzhj 497 12 + + SYM cord-005646-xhx9pzhj 497 13 19.2 19.2 CD cord-005646-xhx9pzhj 497 14 hours hour NNS cord-005646-xhx9pzhj 497 15 . . . cord-005646-xhx9pzhj 498 1 The the DT cord-005646-xhx9pzhj 498 2 mean mean JJ cord-005646-xhx9pzhj 498 3 PRISM prism NN cord-005646-xhx9pzhj 498 4 score score NN cord-005646-xhx9pzhj 498 5 upon upon IN cord-005646-xhx9pzhj 498 6 hospital hospital NN cord-005646-xhx9pzhj 498 7 admission admission NN cord-005646-xhx9pzhj 498 8 was be VBD cord-005646-xhx9pzhj 498 9 30 30 CD cord-005646-xhx9pzhj 498 10 + + SYM cord-005646-xhx9pzhj 498 11 13.7 13.7 CD cord-005646-xhx9pzhj 499 1 ( ( -LRB- cord-005646-xhx9pzhj 499 2 score score NN cord-005646-xhx9pzhj 500 1 > > XX cord-005646-xhx9pzhj 501 1 20 20 CD cord-005646-xhx9pzhj 501 2 = = NFP cord-005646-xhx9pzhj 502 1 > > XX cord-005646-xhx9pzhj 502 2 50 50 CD cord-005646-xhx9pzhj 502 3 % % NN cord-005646-xhx9pzhj 502 4 mortality mortality NN cord-005646-xhx9pzhj 502 5 ) ) -RRB- cord-005646-xhx9pzhj 502 6 . . . cord-005646-xhx9pzhj 503 1 79 79 CD cord-005646-xhx9pzhj 503 2 % % NN cord-005646-xhx9pzhj 503 3 ( ( -LRB- cord-005646-xhx9pzhj 503 4 11/14 11/14 CD cord-005646-xhx9pzhj 503 5 ) ) -RRB- cord-005646-xhx9pzhj 503 6 of of IN cord-005646-xhx9pzhj 503 7 the the DT cord-005646-xhx9pzhj 503 8 patients patient NNS cord-005646-xhx9pzhj 503 9 died die VBD cord-005646-xhx9pzhj 503 10 . . . cord-005646-xhx9pzhj 504 1 One one CD cord-005646-xhx9pzhj 504 2 of of IN cord-005646-xhx9pzhj 504 3 the the DT cord-005646-xhx9pzhj 504 4 three three CD cord-005646-xhx9pzhj 504 5 survivors survivor NNS cord-005646-xhx9pzhj 504 6 had have VBD cord-005646-xhx9pzhj 504 7 severe severe JJ cord-005646-xhx9pzhj 504 8 neurologie neurologie JJ cord-005646-xhx9pzhj 504 9 injury injury NN cord-005646-xhx9pzhj 504 10 . . . cord-005646-xhx9pzhj 505 1 Prior prior RB cord-005646-xhx9pzhj 505 2 to to IN cord-005646-xhx9pzhj 505 3 PICU PICU NNP cord-005646-xhx9pzhj 505 4 admission admission NN cord-005646-xhx9pzhj 505 5 , , , cord-005646-xhx9pzhj 505 6 patients patient NNS cord-005646-xhx9pzhj 505 7 experienced experience VBD cord-005646-xhx9pzhj 505 8 tac~,cardia tac~,cardia CD cord-005646-xhx9pzhj 505 9 ( ( -LRB- cord-005646-xhx9pzhj 505 10 n=9 n=9 NN cord-005646-xhx9pzhj 505 11 ) ) -RRB- cord-005646-xhx9pzhj 505 12 , , , cord-005646-xhx9pzhj 505 13 hypotension hypotension NN cord-005646-xhx9pzhj 505 14 ( ( -LRB- cord-005646-xhx9pzhj 505 15 n=8 n=8 NN cord-005646-xhx9pzhj 505 16 ) ) -RRB- cord-005646-xhx9pzhj 505 17 , , , cord-005646-xhx9pzhj 505 18 neurological neurological JJ cord-005646-xhx9pzhj 505 19 deterioration deterioration NN cord-005646-xhx9pzhj 505 20 ( ( -LRB- cord-005646-xhx9pzhj 505 21 n=8 n=8 NN cord-005646-xhx9pzhj 505 22 ) ) -RRB- cord-005646-xhx9pzhj 505 23 , , , cord-005646-xhx9pzhj 505 24 respiratory respiratory JJ cord-005646-xhx9pzhj 505 25 , , , cord-005646-xhx9pzhj 505 26 distress distress NN cord-005646-xhx9pzhj 505 27 ( ( -LRB- cord-005646-xhx9pzhj 505 28 n=7 n=7 NNS cord-005646-xhx9pzhj 505 29 ) ) -RRB- cord-005646-xhx9pzhj 505 30 , , , cord-005646-xhx9pzhj 505 31 oliguria oliguria FW cord-005646-xhx9pzhj 505 32 ( ( -LRB- cord-005646-xhx9pzhj 505 33 n=5 n=5 NNP cord-005646-xhx9pzhj 505 34 ) ) -RRB- cord-005646-xhx9pzhj 505 35 , , , cord-005646-xhx9pzhj 505 36 bradycardia bradycardia JJ cord-005646-xhx9pzhj 505 37 ( ( -LRB- cord-005646-xhx9pzhj 505 38 n=3 n=3 NN cord-005646-xhx9pzhj 505 39 ) ) -RRB- cord-005646-xhx9pzhj 505 40 , , , cord-005646-xhx9pzhj 505 41 metabolic metabolic JJ cord-005646-xhx9pzhj 505 42 acidosis acidosis NN cord-005646-xhx9pzhj 505 43 ( ( -LRB- cord-005646-xhx9pzhj 505 44 n=7 n=7 NNS cord-005646-xhx9pzhj 505 45 ) ) -RRB- cord-005646-xhx9pzhj 505 46 , , , cord-005646-xhx9pzhj 505 47 hyponatremia hyponatremia NN cord-005646-xhx9pzhj 505 48 ( ( -LRB- cord-005646-xhx9pzhj 505 49 n=4 n=4 NNS cord-005646-xhx9pzhj 505 50 ) ) -RRB- cord-005646-xhx9pzhj 505 51 , , , cord-005646-xhx9pzhj 505 52 hypokalemia hypokalemia NN cord-005646-xhx9pzhj 505 53 ( ( -LRB- cord-005646-xhx9pzhj 505 54 n=2 n=2 NNS cord-005646-xhx9pzhj 505 55 ) ) -RRB- cord-005646-xhx9pzhj 505 56 , , , cord-005646-xhx9pzhj 505 57 hypocalcemia hypocalcemia NN cord-005646-xhx9pzhj 505 58 ( ( -LRB- cord-005646-xhx9pzhj 505 59 n=2 n=2 NNS cord-005646-xhx9pzhj 505 60 ) ) -RRB- cord-005646-xhx9pzhj 505 61 and and CC cord-005646-xhx9pzhj 505 62 severe severe JJ cord-005646-xhx9pzhj 505 63 hypoglycemia hypoglycemia NN cord-005646-xhx9pzhj 505 64 ( ( -LRB- cord-005646-xhx9pzhj 505 65 n=2 n=2 NNS cord-005646-xhx9pzhj 505 66 ) ) -RRB- cord-005646-xhx9pzhj 505 67 . . . cord-005646-xhx9pzhj 506 1 There there EX cord-005646-xhx9pzhj 506 2 were be VBD cord-005646-xhx9pzhj 506 3 serious serious JJ cord-005646-xhx9pzhj 506 4 delays delay NNS cord-005646-xhx9pzhj 506 5 from from IN cord-005646-xhx9pzhj 506 6 the the DT cord-005646-xhx9pzhj 506 7 time time NN cord-005646-xhx9pzhj 506 8 of of IN cord-005646-xhx9pzhj 506 9 development development NN cord-005646-xhx9pzhj 506 10 of of IN cord-005646-xhx9pzhj 506 11 clinical clinical JJ cord-005646-xhx9pzhj 506 12 and and CC cord-005646-xhx9pzhj 506 13 laboratory laboratory NN cord-005646-xhx9pzhj 506 14 abnormalities abnormality NNS cord-005646-xhx9pzhj 506 15 to to IN cord-005646-xhx9pzhj 506 16 the the DT cord-005646-xhx9pzhj 506 17 time time NN cord-005646-xhx9pzhj 506 18 of of IN cord-005646-xhx9pzhj 506 19 admission admission NN cord-005646-xhx9pzhj 506 20 to to IN cord-005646-xhx9pzhj 506 21 PICU PICU NNP cord-005646-xhx9pzhj 506 22 . . . cord-005646-xhx9pzhj 507 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 507 2 : : : cord-005646-xhx9pzhj 508 1 In in IN cord-005646-xhx9pzhj 508 2 the the DT cord-005646-xhx9pzhj 508 3 critically critically RB cord-005646-xhx9pzhj 508 4 ill ill JJ cord-005646-xhx9pzhj 508 5 pediatric pediatric JJ cord-005646-xhx9pzhj 508 6 patient patient NN cord-005646-xhx9pzhj 508 7 , , , cord-005646-xhx9pzhj 508 8 rapid rapid JJ cord-005646-xhx9pzhj 508 9 recognition recognition NN cord-005646-xhx9pzhj 508 10 of of IN cord-005646-xhx9pzhj 508 11 clinical clinical JJ cord-005646-xhx9pzhj 508 12 and and CC cord-005646-xhx9pzhj 508 13 laboratory laboratory NN cord-005646-xhx9pzhj 508 14 signs sign NNS cord-005646-xhx9pzhj 508 15 of of IN cord-005646-xhx9pzhj 508 16 deterioration deterioration NN cord-005646-xhx9pzhj 508 17 , , , cord-005646-xhx9pzhj 508 18 followed follow VBN cord-005646-xhx9pzhj 508 19 by by IN cord-005646-xhx9pzhj 508 20 immediate immediate JJ cord-005646-xhx9pzhj 508 21 intervention intervention NN cord-005646-xhx9pzhj 508 22 , , , cord-005646-xhx9pzhj 508 23 are be VBP cord-005646-xhx9pzhj 508 24 required require VBN cord-005646-xhx9pzhj 508 25 to to TO cord-005646-xhx9pzhj 508 26 prevent prevent VB cord-005646-xhx9pzhj 508 27 end end NN cord-005646-xhx9pzhj 508 28 stage stage NN cord-005646-xhx9pzhj 508 29 shock shock NN cord-005646-xhx9pzhj 508 30 and and CC cord-005646-xhx9pzhj 508 31 CPA cpa NN cord-005646-xhx9pzhj 508 32 . . . cord-005646-xhx9pzhj 509 1 We -PRON- PRP cord-005646-xhx9pzhj 509 2 found find VBD cord-005646-xhx9pzhj 509 3 serious serious JJ cord-005646-xhx9pzhj 509 4 delays delay NNS cord-005646-xhx9pzhj 509 5 in in IN cord-005646-xhx9pzhj 509 6 intervention intervention NN cord-005646-xhx9pzhj 509 7 following follow VBG cord-005646-xhx9pzhj 509 8 development development NN cord-005646-xhx9pzhj 509 9 of of IN cord-005646-xhx9pzhj 509 10 important important JJ cord-005646-xhx9pzhj 509 11 premonitory premonitory JJ cord-005646-xhx9pzhj 509 12 clinical clinical JJ cord-005646-xhx9pzhj 509 13 and and CC cord-005646-xhx9pzhj 509 14 laboratory laboratory NN cord-005646-xhx9pzhj 509 15 abnormalities abnormality NNS cord-005646-xhx9pzhj 509 16 in in IN cord-005646-xhx9pzhj 509 17 patients patient NNS cord-005646-xhx9pzhj 509 18 less less JJR cord-005646-xhx9pzhj 509 19 than than IN cord-005646-xhx9pzhj 509 20 20 20 CD cord-005646-xhx9pzhj 509 21 months month NNS cord-005646-xhx9pzhj 509 22 of of IN cord-005646-xhx9pzhj 509 23 age age NN cord-005646-xhx9pzhj 509 24 on on IN cord-005646-xhx9pzhj 509 25 the the DT cord-005646-xhx9pzhj 509 26 general general JJ cord-005646-xhx9pzhj 509 27 pediatric pediatric JJ cord-005646-xhx9pzhj 509 28 wards ward NNS cord-005646-xhx9pzhj 509 29 , , , cord-005646-xhx9pzhj 509 30 which which WDT cord-005646-xhx9pzhj 509 31 Iikely Iikely NNP cord-005646-xhx9pzhj 509 32 contributed contribute VBD cord-005646-xhx9pzhj 509 33 to to IN cord-005646-xhx9pzhj 509 34 the the DT cord-005646-xhx9pzhj 509 35 dismal dismal JJ cord-005646-xhx9pzhj 509 36 79 79 CD cord-005646-xhx9pzhj 509 37 % % NN cord-005646-xhx9pzhj 509 38 mortality mortality NN cord-005646-xhx9pzhj 509 39 rate rate NN cord-005646-xhx9pzhj 509 40 . . . cord-005646-xhx9pzhj 510 1 Hospitals hospital NNS cord-005646-xhx9pzhj 510 2 throughout throughout IN cord-005646-xhx9pzhj 510 3 Ecuador Ecuador NNP cord-005646-xhx9pzhj 510 4 should should MD cord-005646-xhx9pzhj 510 5 institute institute VB cord-005646-xhx9pzhj 510 6 immediate immediate JJ cord-005646-xhx9pzhj 510 7 improvements improvement NNS cord-005646-xhx9pzhj 510 8 in in IN cord-005646-xhx9pzhj 510 9 ctinical ctinical JJ cord-005646-xhx9pzhj 510 10 supervision supervision NN cord-005646-xhx9pzhj 510 11 , , , cord-005646-xhx9pzhj 510 12 and and CC cord-005646-xhx9pzhj 510 13 provide provide VB cord-005646-xhx9pzhj 510 14 training training NN cord-005646-xhx9pzhj 510 15 in in IN cord-005646-xhx9pzhj 510 16 paediatric paediatric JJ cord-005646-xhx9pzhj 510 17 advanced advanced JJ cord-005646-xhx9pzhj 510 18 life life NN cord-005646-xhx9pzhj 510 19 support support NN cord-005646-xhx9pzhj 510 20 ( ( -LRB- cord-005646-xhx9pzhj 510 21 PALS pals NN cord-005646-xhx9pzhj 510 22 ) ) -RRB- cord-005646-xhx9pzhj 510 23 to to TO cord-005646-xhx9pzhj 510 24 decrease decrease VB cord-005646-xhx9pzhj 510 25 excessively excessively RB cord-005646-xhx9pzhj 510 26 high high JJ cord-005646-xhx9pzhj 510 27 rates rate NNS cord-005646-xhx9pzhj 510 28 of of IN cord-005646-xhx9pzhj 510 29 and and CC cord-005646-xhx9pzhj 510 30 mortality mortality NN cord-005646-xhx9pzhj 510 31 from from IN cord-005646-xhx9pzhj 510 32 CPA cpa NN cord-005646-xhx9pzhj 510 33 . . . cord-005646-xhx9pzhj 511 1 intraosscous intraosscous NNP cord-005646-xhx9pzhj 511 2 access access NNP cord-005646-xhx9pzhj 511 3 is be VBZ cord-005646-xhx9pzhj 511 4 recommended recommend VBN cord-005646-xhx9pzhj 511 5 by by IN cord-005646-xhx9pzhj 511 6 the the DT cord-005646-xhx9pzhj 511 7 American American NNP cord-005646-xhx9pzhj 511 8 Heart Heart NNP cord-005646-xhx9pzhj 511 9 Association Association NNP cord-005646-xhx9pzhj 511 10 and and CC cord-005646-xhx9pzhj 511 11 American American NNP cord-005646-xhx9pzhj 511 12 Academy Academy NNP cord-005646-xhx9pzhj 511 13 of of IN cord-005646-xhx9pzhj 511 14 Pediatries Pediatries NNP cord-005646-xhx9pzhj 511 15 as as IN cord-005646-xhx9pzhj 511 16 a a DT cord-005646-xhx9pzhj 511 17 means means NN cord-005646-xhx9pzhj 511 18 of of IN cord-005646-xhx9pzhj 511 19 rapid rapid JJ cord-005646-xhx9pzhj 511 20 access access NN cord-005646-xhx9pzhj 511 21 to to IN cord-005646-xhx9pzhj 511 22 the the DT cord-005646-xhx9pzhj 511 23 vascular vascular JJ cord-005646-xhx9pzhj 511 24 system system NN cord-005646-xhx9pzhj 511 25 for for IN cord-005646-xhx9pzhj 511 26 childhood childhood NN cord-005646-xhx9pzhj 511 27 emergencies emergency NNS cord-005646-xhx9pzhj 511 28 . . . cord-005646-xhx9pzhj 512 1 Bone bone NN cord-005646-xhx9pzhj 512 2 marrow marrow NN cord-005646-xhx9pzhj 512 3 and and CC cord-005646-xhx9pzhj 512 4 fat fat JJ cord-005646-xhx9pzhj 512 5 embolism embolism NN cord-005646-xhx9pzhj 512 6 is be VBZ cord-005646-xhx9pzhj 512 7 a a DT cord-005646-xhx9pzhj 512 8 concern concern NN cord-005646-xhx9pzhj 512 9 and and CC cord-005646-xhx9pzhj 512 10 has have VBZ cord-005646-xhx9pzhj 512 11 been be VBN cord-005646-xhx9pzhj 512 12 reported report VBN cord-005646-xhx9pzhj 512 13 post post JJ cord-005646-xhx9pzhj 512 14 intraosseous intraosseous JJ cord-005646-xhx9pzhj 512 15 infusion infusion NN cord-005646-xhx9pzhj 512 16 in in IN cord-005646-xhx9pzhj 512 17 stable stable JJ cord-005646-xhx9pzhj 512 18 animals animal NNS cord-005646-xhx9pzhj 512 19 but but CC cord-005646-xhx9pzhj 512 20 has have VBZ cord-005646-xhx9pzhj 512 21 never never RB cord-005646-xhx9pzhj 512 22 been be VBN cord-005646-xhx9pzhj 512 23 studied study VBN cord-005646-xhx9pzhj 512 24 in in IN cord-005646-xhx9pzhj 512 25 animals animal NNS cord-005646-xhx9pzhj 512 26 subjected subject VBN cord-005646-xhx9pzhj 512 27 to to IN cord-005646-xhx9pzhj 512 28 cardiopuimonary cardiopuimonary JJ cord-005646-xhx9pzhj 512 29 resuscitation resuscitation NN cord-005646-xhx9pzhj 512 30 . . . cord-005646-xhx9pzhj 513 1 We -PRON- PRP cord-005646-xhx9pzhj 513 2 undertook undertake VBD cord-005646-xhx9pzhj 513 3 this this DT cord-005646-xhx9pzhj 513 4 study study NN cord-005646-xhx9pzhj 513 5 to to TO cord-005646-xhx9pzhj 513 6 investigate investigate VB cord-005646-xhx9pzhj 513 7 the the DT cord-005646-xhx9pzhj 513 8 incidence incidence NN cord-005646-xhx9pzhj 513 9 and and CC cord-005646-xhx9pzhj 513 10 magnitude magnitude NN cord-005646-xhx9pzhj 513 11 of of IN cord-005646-xhx9pzhj 513 12 lat lat NN cord-005646-xhx9pzhj 513 13 and and CC cord-005646-xhx9pzhj 513 14 bone bone NN cord-005646-xhx9pzhj 513 15 marrow marrow NN cord-005646-xhx9pzhj 513 16 embolism embolism NN cord-005646-xhx9pzhj 513 17 with with IN cord-005646-xhx9pzhj 513 18 the the DT cord-005646-xhx9pzhj 513 19 use use NN cord-005646-xhx9pzhj 513 20 of of IN cord-005646-xhx9pzhj 513 21 intraosseous intraosseous JJ cord-005646-xhx9pzhj 513 22 infusion infusion NN cord-005646-xhx9pzhj 513 23 during during IN cord-005646-xhx9pzhj 513 24 prolonged prolong VBN cord-005646-xhx9pzhj 513 25 cardiopuhaonary cardiopuhaonary JJ cord-005646-xhx9pzhj 513 26 resuscitation resuscitation NN cord-005646-xhx9pzhj 513 27 and and CC cord-005646-xhx9pzhj 513 28 after after IN cord-005646-xhx9pzhj 513 29 fluid fluid NN cord-005646-xhx9pzhj 513 30 and and CC cord-005646-xhx9pzhj 513 31 drug drug NN cord-005646-xhx9pzhj 513 32 infusion infusion NN cord-005646-xhx9pzhj 513 33 . . . cord-005646-xhx9pzhj 514 1 We -PRON- PRP cord-005646-xhx9pzhj 514 2 hypothesized hypothesize VBD cord-005646-xhx9pzhj 514 3 that that IN cord-005646-xhx9pzhj 514 4 there there EX cord-005646-xhx9pzhj 514 5 will will MD cord-005646-xhx9pzhj 514 6 be be VB cord-005646-xhx9pzhj 514 7 no no DT cord-005646-xhx9pzhj 514 8 difference difference NN cord-005646-xhx9pzhj 514 9 in in IN cord-005646-xhx9pzhj 514 10 the the DT cord-005646-xhx9pzhj 514 11 magnitude magnitude NN cord-005646-xhx9pzhj 514 12 of of IN cord-005646-xhx9pzhj 514 13 fat fat JJ cord-005646-xhx9pzhj 514 14 embolism embolism NN cord-005646-xhx9pzhj 514 15 between between IN cord-005646-xhx9pzhj 514 16 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 514 17 resuscitation resuscitation NN cord-005646-xhx9pzhj 514 18 only only RB cord-005646-xhx9pzhj 514 19 and and CC cord-005646-xhx9pzhj 514 20 other other JJ cord-005646-xhx9pzhj 514 21 cxperirnental cxperirnental NNP cord-005646-xhx9pzhj 514 22 conditions condition NNS cord-005646-xhx9pzhj 514 23 . . . cord-005646-xhx9pzhj 515 1 Thirty thirty CD cord-005646-xhx9pzhj 515 2 - - HYPH cord-005646-xhx9pzhj 515 3 one one CD cord-005646-xhx9pzhj 515 4 ( ( -LRB- cord-005646-xhx9pzhj 515 5 31 31 CD cord-005646-xhx9pzhj 515 6 ) ) -RRB- cord-005646-xhx9pzhj 515 7 piglets piglet NNS cord-005646-xhx9pzhj 515 8 were be VBD cord-005646-xhx9pzhj 515 9 anesthetized anesthetize VBN cord-005646-xhx9pzhj 515 10 , , , cord-005646-xhx9pzhj 515 11 mechanically mechanically RB cord-005646-xhx9pzhj 515 12 ventilated ventilate VBN cord-005646-xhx9pzhj 515 13 , , , cord-005646-xhx9pzhj 515 14 and and CC cord-005646-xhx9pzhj 515 15 instrumented instrument VBN cord-005646-xhx9pzhj 515 16 ( ( -LRB- cord-005646-xhx9pzhj 515 17 carotid carotid JJ cord-005646-xhx9pzhj 515 18 artery artery NN cord-005646-xhx9pzhj 515 19 , , , cord-005646-xhx9pzhj 515 20 pulmonary pulmonary JJ cord-005646-xhx9pzhj 515 21 artery artery NN cord-005646-xhx9pzhj 515 22 and and CC cord-005646-xhx9pzhj 515 23 intraosseous intraosseous JJ cord-005646-xhx9pzhj 515 24 earmulas earmulas NNP cord-005646-xhx9pzhj 515 25 ) ) -RRB- cord-005646-xhx9pzhj 515 26 . . . cord-005646-xhx9pzhj 516 1 The the DT cord-005646-xhx9pzhj 516 2 animals animal NNS cord-005646-xhx9pzhj 516 3 then then RB cord-005646-xhx9pzhj 516 4 underwent undergo VBD cord-005646-xhx9pzhj 516 5 bypoxic bypoxic JJ cord-005646-xhx9pzhj 516 6 cardiac cardiac JJ cord-005646-xhx9pzhj 516 7 arrest arrest NN cord-005646-xhx9pzhj 516 8 followed follow VBN cord-005646-xhx9pzhj 516 9 by by IN cord-005646-xhx9pzhj 516 10 chest chest NN cord-005646-xhx9pzhj 516 11 compressions compression NNS cord-005646-xhx9pzhj 516 12 with with IN cord-005646-xhx9pzhj 516 13 the the DT cord-005646-xhx9pzhj 516 14 mechanical mechanical JJ cord-005646-xhx9pzhj 516 15 thumper thumper NN cord-005646-xhx9pzhj 516 16 ( ( -LRB- cord-005646-xhx9pzhj 516 17 Michigan Michigan NNP cord-005646-xhx9pzhj 516 18 Insmunents Insmunents NNP cord-005646-xhx9pzhj 516 19 ) ) -RRB- cord-005646-xhx9pzhj 516 20 and and CC cord-005646-xhx9pzhj 516 21 mechanical mechanical JJ cord-005646-xhx9pzhj 516 22 ventilation ventilation NN cord-005646-xhx9pzhj 516 23 for for IN cord-005646-xhx9pzhj 516 24 a a DT cord-005646-xhx9pzhj 516 25 minimum minimum NN cord-005646-xhx9pzhj 516 26 of of IN cord-005646-xhx9pzhj 516 27 45 45 CD cord-005646-xhx9pzhj 516 28 minutes minute NNS cord-005646-xhx9pzhj 516 29 . . . cord-005646-xhx9pzhj 517 1 The the DT cord-005646-xhx9pzhj 517 2 animals animal NNS cord-005646-xhx9pzhj 517 3 were be VBD cord-005646-xhx9pzhj 517 4 divided divide VBN cord-005646-xhx9pzhj 517 5 in in IN cord-005646-xhx9pzhj 517 6 groups group NNS cord-005646-xhx9pzhj 517 7 : : : cord-005646-xhx9pzhj 517 8 A a DT cord-005646-xhx9pzhj 517 9 ( ( -LRB- cord-005646-xhx9pzhj 517 10 n=5 n=5 JJ cord-005646-xhx9pzhj 517 11 ) ) -RRB- cord-005646-xhx9pzhj 517 12 which which WDT cord-005646-xhx9pzhj 517 13 had have VBD cord-005646-xhx9pzhj 517 14 no no DT cord-005646-xhx9pzhj 517 15 intraosseous intraosseous JJ cord-005646-xhx9pzhj 517 16 , , . cord-005646-xhx9pzhj 518 1 ~'oup ~'oup NFP cord-005646-xhx9pzhj 519 1 B B NNP cord-005646-xhx9pzhj 519 2 ( ( -LRB- cord-005646-xhx9pzhj 519 3 n=6 n=6 NNP cord-005646-xhx9pzhj 519 4 ) ) -RRB- cord-005646-xhx9pzhj 519 5 had have VBD cord-005646-xhx9pzhj 519 6 intraosscous intraosscous JJ cord-005646-xhx9pzhj 519 7 with with IN cord-005646-xhx9pzhj 520 1 no no DT cord-005646-xhx9pzhj 520 2 infi infi NNP cord-005646-xhx9pzhj 520 3 ~ ~ NFP cord-005646-xhx9pzhj 520 4 ion ion NN cord-005646-xhx9pzhj 520 5 , , , cord-005646-xhx9pzhj 520 6 and and CC cord-005646-xhx9pzhj 520 7 groups group NNS cord-005646-xhx9pzhj 520 8 C C NNP cord-005646-xhx9pzhj 520 9 ( ( -LRB- cord-005646-xhx9pzhj 520 10 n=6 n=6 NNP cord-005646-xhx9pzhj 520 11 ) ) -RRB- cord-005646-xhx9pzhj 520 12 , , , cord-005646-xhx9pzhj 520 13 D D NNP cord-005646-xhx9pzhj 520 14 ( ( -LRB- cord-005646-xhx9pzhj 520 15 n=6 n=6 NNP cord-005646-xhx9pzhj 520 16 ) ) -RRB- cord-005646-xhx9pzhj 520 17 , , , cord-005646-xhx9pzhj 520 18 E E NNP cord-005646-xhx9pzhj 520 19 ( ( -LRB- cord-005646-xhx9pzhj 520 20 n=8 n=8 NNP cord-005646-xhx9pzhj 520 21 ) ) -RRB- cord-005646-xhx9pzhj 520 22 had have VBD cord-005646-xhx9pzhj 520 23 intraosseous intraosseous JJ cord-005646-xhx9pzhj 520 24 with with IN cord-005646-xhx9pzhj 520 25 infusion infusion NN cord-005646-xhx9pzhj 520 26 of of IN cord-005646-xhx9pzhj 520 27 adrenaline adrenaline NN cord-005646-xhx9pzhj 520 28 , , , cord-005646-xhx9pzhj 520 29 normal normal JJ cord-005646-xhx9pzhj 520 30 saline saline NN cord-005646-xhx9pzhj 520 31 and and CC cord-005646-xhx9pzhj 520 32 sodium sodium NN cord-005646-xhx9pzhj 520 33 bicarbonate bicarbonate NN cord-005646-xhx9pzhj 520 34 , , , cord-005646-xhx9pzhj 521 1 At at IN cord-005646-xhx9pzhj 521 2 cessation cessation NN cord-005646-xhx9pzhj 521 3 ofcardiopulmonary ofcardiopulmonary JJ cord-005646-xhx9pzhj 521 4 resuscitation resuscitation NN cord-005646-xhx9pzhj 521 5 , , , cord-005646-xhx9pzhj 521 6 representative representative JJ cord-005646-xhx9pzhj 521 7 lung lung NN cord-005646-xhx9pzhj 521 8 samples sample NNS cord-005646-xhx9pzhj 521 9 were be VBD cord-005646-xhx9pzhj 521 10 collected collect VBN cord-005646-xhx9pzhj 521 11 fi'om fi'om NN cord-005646-xhx9pzhj 521 12 upper upper NN cord-005646-xhx9pzhj 521 13 and and CC cord-005646-xhx9pzhj 521 14 lower low JJR cord-005646-xhx9pzhj 521 15 lobes lobe NNS cord-005646-xhx9pzhj 521 16 of of IN cord-005646-xhx9pzhj 521 17 each each DT cord-005646-xhx9pzhj 521 18 lung lung NN cord-005646-xhx9pzhj 521 19 , , , cord-005646-xhx9pzhj 521 20 embedded embed VBN cord-005646-xhx9pzhj 521 21 in in IN cord-005646-xhx9pzhj 521 22 OCP OCP NNP cord-005646-xhx9pzhj 521 23 and and CC cord-005646-xhx9pzhj 521 24 firozen firozen NN cord-005646-xhx9pzhj 521 25 immediately immediately RB cord-005646-xhx9pzhj 521 26 . . . cord-005646-xhx9pzhj 522 1 Ltmg Ltmg NNP cord-005646-xhx9pzhj 522 2 specimens specimen NNS cord-005646-xhx9pzhj 522 3 were be VBD cord-005646-xhx9pzhj 522 4 stained stain VBN cord-005646-xhx9pzhj 522 5 using use VBG cord-005646-xhx9pzhj 522 6 Oil Oil NNP cord-005646-xhx9pzhj 522 7 Red Red NNP cord-005646-xhx9pzhj 522 8 - - HYPH cord-005646-xhx9pzhj 522 9 O o NN cord-005646-xhx9pzhj 522 10 dye dye NN cord-005646-xhx9pzhj 522 11 and and CC cord-005646-xhx9pzhj 522 12 observed observe VBD cord-005646-xhx9pzhj 522 13 for for IN cord-005646-xhx9pzhj 522 14 fat fat JJ cord-005646-xhx9pzhj 522 15 globules globule NNS cord-005646-xhx9pzhj 522 16 and and CC cord-005646-xhx9pzhj 522 17 bone bone NN cord-005646-xhx9pzhj 522 18 marrow marrow NN cord-005646-xhx9pzhj 522 19 elements element NNS cord-005646-xhx9pzhj 522 20 . . . cord-005646-xhx9pzhj 523 1 The the DT cord-005646-xhx9pzhj 523 2 amount amount NN cord-005646-xhx9pzhj 523 3 of of IN cord-005646-xhx9pzhj 523 4 emboli emboli NN cord-005646-xhx9pzhj 523 5 present present JJ cord-005646-xhx9pzhj 523 6 was be VBD cord-005646-xhx9pzhj 523 7 rated rate VBN cord-005646-xhx9pzhj 523 8 as as IN cord-005646-xhx9pzhj 523 9 a a DT cord-005646-xhx9pzhj 523 10 percentage percentage NN cord-005646-xhx9pzhj 523 11 in in IN cord-005646-xhx9pzhj 523 12 relationship relationship NN cord-005646-xhx9pzhj 523 13 to to IN cord-005646-xhx9pzhj 523 14 Iung Iung NNP cord-005646-xhx9pzhj 523 15 tissue tissue NN cord-005646-xhx9pzhj 523 16 , , , cord-005646-xhx9pzhj 523 17 by by IN cord-005646-xhx9pzhj 523 18 a a DT cord-005646-xhx9pzhj 523 19 pathologist pathologist NN cord-005646-xhx9pzhj 523 20 blinded blind VBN cord-005646-xhx9pzhj 523 21 to to IN cord-005646-xhx9pzhj 523 22 the the DT cord-005646-xhx9pzhj 523 23 experimental experimental JJ cord-005646-xhx9pzhj 523 24 groups group NNS cord-005646-xhx9pzhj 523 25 . . . cord-005646-xhx9pzhj 524 1 Buffy Buffy NNP cord-005646-xhx9pzhj 524 2 coat coat NN cord-005646-xhx9pzhj 524 3 specimens specimen NNS cord-005646-xhx9pzhj 524 4 were be VBD cord-005646-xhx9pzhj 524 5 collected collect VBN cord-005646-xhx9pzhj 524 6 before before RB cord-005646-xhx9pzhj 524 7 and and CC cord-005646-xhx9pzhj 524 8 at at IN cord-005646-xhx9pzhj 524 9 cessation cessation NN cord-005646-xhx9pzhj 524 10 of of IN cord-005646-xhx9pzhj 524 11 cardiopuimonary cardiopuimonary JJ cord-005646-xhx9pzhj 524 12 resuscitation resuscitation NN cord-005646-xhx9pzhj 524 13 , , , cord-005646-xhx9pzhj 524 14 stained stain VBN cord-005646-xhx9pzhj 524 15 with with IN cord-005646-xhx9pzhj 524 16 Oil Oil NNP cord-005646-xhx9pzhj 524 17 Red Red NNP cord-005646-xhx9pzhj 524 18 - - HYPH cord-005646-xhx9pzhj 524 19 O o NN cord-005646-xhx9pzhj 524 20 dye dye NN cord-005646-xhx9pzhj 524 21 and and CC cord-005646-xhx9pzhj 524 22 observed observe VBD cord-005646-xhx9pzhj 524 23 for for IN cord-005646-xhx9pzhj 524 24 fat fat JJ cord-005646-xhx9pzhj 524 25 globules globule NNS cord-005646-xhx9pzhj 524 26 . . . cord-005646-xhx9pzhj 525 1 Percentage percentage NN cord-005646-xhx9pzhj 525 2 of of IN cord-005646-xhx9pzhj 525 3 fat fat JJ cord-005646-xhx9pzhj 525 4 present present JJ cord-005646-xhx9pzhj 525 5 were be VBD cord-005646-xhx9pzhj 525 6 compared compare VBN cord-005646-xhx9pzhj 525 7 using use VBG cord-005646-xhx9pzhj 525 8 analysis analysis NN cord-005646-xhx9pzhj 525 9 of of IN cord-005646-xhx9pzhj 525 10 variance variance NN cord-005646-xhx9pzhj 525 11 . . . cord-005646-xhx9pzhj 526 1 Fat fat JJ cord-005646-xhx9pzhj 526 2 globules globule NNS cord-005646-xhx9pzhj 526 3 were be VBD cord-005646-xhx9pzhj 526 4 seen see VBN cord-005646-xhx9pzhj 526 5 in in IN cord-005646-xhx9pzhj 526 6 the the DT cord-005646-xhx9pzhj 526 7 prebronchial prebronchial JJ cord-005646-xhx9pzhj 526 8 blood blood NN cord-005646-xhx9pzhj 526 9 vessels vessel NNS cord-005646-xhx9pzhj 526 10 and and CC cord-005646-xhx9pzhj 526 11 in in IN cord-005646-xhx9pzhj 526 12 intravascular intravascular JJ cord-005646-xhx9pzhj 526 13 areas area NNS cord-005646-xhx9pzhj 526 14 throughout throughout IN cord-005646-xhx9pzhj 526 15 all all DT cord-005646-xhx9pzhj 526 16 lung lung NN cord-005646-xhx9pzhj 526 17 fields field NNS cord-005646-xhx9pzhj 526 18 . . . cord-005646-xhx9pzhj 527 1 There there EX cord-005646-xhx9pzhj 527 2 was be VBD cord-005646-xhx9pzhj 527 3 no no DT cord-005646-xhx9pzhj 527 4 difference difference NN cord-005646-xhx9pzhj 527 5 in in IN cord-005646-xhx9pzhj 527 6 appearance appearance NN cord-005646-xhx9pzhj 527 7 or or CC cord-005646-xhx9pzhj 527 8 distribution distribution NN cord-005646-xhx9pzhj 527 9 of of IN cord-005646-xhx9pzhj 527 10 fat fat JJ cord-005646-xhx9pzhj 527 11 globules globule NNS cord-005646-xhx9pzhj 527 12 between between IN cord-005646-xhx9pzhj 527 13 groups group NNS cord-005646-xhx9pzhj 527 14 . . . cord-005646-xhx9pzhj 528 1 Quantity quantity NN cord-005646-xhx9pzhj 528 2 varied varied JJ cord-005646-xhx9pzhj 528 3 in in IN cord-005646-xhx9pzhj 528 4 the the DT cord-005646-xhx9pzhj 528 5 different different JJ cord-005646-xhx9pzhj 528 6 groups[(A groups[(A NNP cord-005646-xhx9pzhj 528 7 ) ) -RRB- cord-005646-xhx9pzhj 528 8 45 45 CD cord-005646-xhx9pzhj 528 9 % % NN cord-005646-xhx9pzhj 528 10 , , , cord-005646-xhx9pzhj 528 11 ( ( -LRB- cord-005646-xhx9pzhj 528 12 B b NN cord-005646-xhx9pzhj 528 13 ) ) -RRB- cord-005646-xhx9pzhj 529 1 44 44 CD cord-005646-xhx9pzhj 529 2 % % NN cord-005646-xhx9pzhj 529 3 , , , cord-005646-xhx9pzhj 529 4 ( ( -LRB- cord-005646-xhx9pzhj 529 5 C c NN cord-005646-xhx9pzhj 529 6 ) ) -RRB- cord-005646-xhx9pzhj 529 7 30 30 CD cord-005646-xhx9pzhj 529 8 % % NN cord-005646-xhx9pzhj 529 9 ( ( -LRB- cord-005646-xhx9pzhj 529 10 D D NNP cord-005646-xhx9pzhj 529 11 ) ) -RRB- cord-005646-xhx9pzhj 529 12 23 23 CD cord-005646-xhx9pzhj 529 13 % % NN cord-005646-xhx9pzhj 529 14 , , , cord-005646-xhx9pzhj 529 15 ( ( -LRB- cord-005646-xhx9pzhj 529 16 E e NN cord-005646-xhx9pzhj 529 17 ) ) -RRB- cord-005646-xhx9pzhj 529 18 25 25 CD cord-005646-xhx9pzhj 529 19 % % NN cord-005646-xhx9pzhj 529 20 ] ] -RRB- cord-005646-xhx9pzhj 529 21 , , . cord-005646-xhx9pzhj 530 1 but but CC cord-005646-xhx9pzhj 530 2 were be VBD cord-005646-xhx9pzhj 530 3 not not RB cord-005646-xhx9pzhj 530 4 statistically statistically RB cord-005646-xhx9pzhj 530 5 significant significant JJ cord-005646-xhx9pzhj 530 6 ( ( -LRB- cord-005646-xhx9pzhj 530 7 p p NN cord-005646-xhx9pzhj 530 8 = = SYM cord-005646-xhx9pzhj 530 9 .097 .097 CD cord-005646-xhx9pzhj 530 10 ) ) -RRB- cord-005646-xhx9pzhj 530 11 . . . cord-005646-xhx9pzhj 531 1 Fat fat JJ cord-005646-xhx9pzhj 531 2 globules globule NNS cord-005646-xhx9pzhj 531 3 in in IN cord-005646-xhx9pzhj 531 4 the the DT cord-005646-xhx9pzhj 531 5 buffy buffy NNP cord-005646-xhx9pzhj 531 6 coat coat NN cord-005646-xhx9pzhj 531 7 were be VBD cord-005646-xhx9pzhj 531 8 few few JJ cord-005646-xhx9pzhj 531 9 and and CC cord-005646-xhx9pzhj 531 10 inconsistent inconsistent JJ cord-005646-xhx9pzhj 531 11 with with IN cord-005646-xhx9pzhj 531 12 lung lung NN cord-005646-xhx9pzhj 531 13 findings finding NNS cord-005646-xhx9pzhj 531 14 . . . cord-005646-xhx9pzhj 532 1 Fat fat JJ cord-005646-xhx9pzhj 532 2 and and CC cord-005646-xhx9pzhj 532 3 bone bone NN cord-005646-xhx9pzhj 532 4 marrow marrow NN cord-005646-xhx9pzhj 532 5 emboli embolus NNS cord-005646-xhx9pzhj 532 6 were be VBD cord-005646-xhx9pzhj 532 7 present present JJ cord-005646-xhx9pzhj 532 8 in in IN cord-005646-xhx9pzhj 532 9 all all DT cord-005646-xhx9pzhj 532 10 experimental experimental JJ cord-005646-xhx9pzhj 532 11 conditions condition NNS cord-005646-xhx9pzhj 532 12 , , , cord-005646-xhx9pzhj 532 13 The the DT cord-005646-xhx9pzhj 532 14 use use NN cord-005646-xhx9pzhj 532 15 of of IN cord-005646-xhx9pzhj 532 16 the the DT cord-005646-xhx9pzhj 532 17 intraosseous intraosseous JJ cord-005646-xhx9pzhj 532 18 cannula cannula NN cord-005646-xhx9pzhj 532 19 does do VBZ cord-005646-xhx9pzhj 532 20 not not RB cord-005646-xhx9pzhj 532 21 increase increase VB cord-005646-xhx9pzhj 532 22 the the DT cord-005646-xhx9pzhj 532 23 magnitude magnitude NN cord-005646-xhx9pzhj 532 24 of of IN cord-005646-xhx9pzhj 532 25 embolization embolization NN cord-005646-xhx9pzhj 532 26 during during IN cord-005646-xhx9pzhj 532 27 cardiopuimonary cardiopuimonary JJ cord-005646-xhx9pzhj 532 28 resuscitation resuscitation NN cord-005646-xhx9pzhj 532 29 . . . cord-005646-xhx9pzhj 533 1 The the DT cord-005646-xhx9pzhj 533 2 decision decision NN cord-005646-xhx9pzhj 533 3 to to TO cord-005646-xhx9pzhj 533 4 use use VB cord-005646-xhx9pzhj 533 5 the the DT cord-005646-xhx9pzhj 533 6 intraosscous intraosscous JJ cord-005646-xhx9pzhj 533 7 route route NN cord-005646-xhx9pzhj 533 8 should should MD cord-005646-xhx9pzhj 533 9 not not RB cord-005646-xhx9pzhj 533 10 be be VB cord-005646-xhx9pzhj 533 11 influenced influence VBN cord-005646-xhx9pzhj 533 12 by by IN cord-005646-xhx9pzhj 533 13 the the DT cord-005646-xhx9pzhj 533 14 risk risk NN cord-005646-xhx9pzhj 533 15 of of IN cord-005646-xhx9pzhj 533 16 embolization embolization NN cord-005646-xhx9pzhj 533 17 . . . cord-005646-xhx9pzhj 534 1 Tzareva Tzareva NNP cord-005646-xhx9pzhj 534 2 IV/ IV/ NNP cord-005646-xhx9pzhj 534 3 , , , cord-005646-xhx9pzhj 534 4 , , , cord-005646-xhx9pzhj 534 5 MD MD NNP cord-005646-xhx9pzhj 534 6 * * NFP cord-005646-xhx9pzhj 534 7 , , , cord-005646-xhx9pzhj 534 8 Nedialkova Nedialkova NNP cord-005646-xhx9pzhj 534 9 R R NNP cord-005646-xhx9pzhj 534 10 , , , cord-005646-xhx9pzhj 534 11 MD MD NNP cord-005646-xhx9pzhj 535 1 * * NFP cord-005646-xhx9pzhj 535 2 * * NFP cord-005646-xhx9pzhj 535 3 , , , cord-005646-xhx9pzhj 535 4 * * NFP cord-005646-xhx9pzhj 535 5 Dept Dept NNP cord-005646-xhx9pzhj 535 6 . . . cord-005646-xhx9pzhj 536 1 of of IN cord-005646-xhx9pzhj 536 2 PathophysioL PathophysioL NNS cord-005646-xhx9pzhj 536 3 , , , cord-005646-xhx9pzhj 536 4 * * NFP cord-005646-xhx9pzhj 536 5 ~Dept ~dept XX cord-005646-xhx9pzhj 536 6 . . . cord-005646-xhx9pzhj 536 7 of of IN cord-005646-xhx9pzhj 536 8 Child Child NNP cord-005646-xhx9pzhj 536 9 Surg Surg NNP cord-005646-xhx9pzhj 536 10 . . . cord-005646-xhx9pzhj 537 1 and and CC cord-005646-xhx9pzhj 537 2 ICU ICU NNP cord-005646-xhx9pzhj 537 3 , , , cord-005646-xhx9pzhj 537 4 Emergency Emergency NNP cord-005646-xhx9pzhj 537 5 Medical Medical NNP cord-005646-xhx9pzhj 537 6 Institute Institute NNP cord-005646-xhx9pzhj 537 7 PIrogov PIrogov NNP cord-005646-xhx9pzhj 537 8 , , , cord-005646-xhx9pzhj 537 9 Sofia Sofia NNP cord-005646-xhx9pzhj 537 10 , , , cord-005646-xhx9pzhj 537 11 Among among IN cord-005646-xhx9pzhj 537 12 566 566 CD cord-005646-xhx9pzhj 537 13 children child NNS cord-005646-xhx9pzhj 537 14 with with IN cord-005646-xhx9pzhj 537 15 blunt blunt JJ cord-005646-xhx9pzhj 537 16 abdominal abdominal JJ cord-005646-xhx9pzhj 537 17 trauma trauma NN cord-005646-xhx9pzhj 537 18 , , , cord-005646-xhx9pzhj 537 19 treated treat VBN cord-005646-xhx9pzhj 537 20 in in IN cord-005646-xhx9pzhj 537 21 EMI EMI NNP cord-005646-xhx9pzhj 537 22 Pirogov Pirogov NNP cord-005646-xhx9pzhj 537 23 during during IN cord-005646-xhx9pzhj 537 24 the the DT cord-005646-xhx9pzhj 537 25 last last JJ cord-005646-xhx9pzhj 537 26 five five CD cord-005646-xhx9pzhj 537 27 years year NNS cord-005646-xhx9pzhj 537 28 , , , cord-005646-xhx9pzhj 537 29 79 79 CD cord-005646-xhx9pzhj 537 30 children child NNS cord-005646-xhx9pzhj 537 31 had have VBD cord-005646-xhx9pzhj 537 32 serious serious JJ cord-005646-xhx9pzhj 537 33 disturbances disturbance NNS cord-005646-xhx9pzhj 537 34 of of IN cord-005646-xhx9pzhj 537 35 the the DT cord-005646-xhx9pzhj 537 36 basic basic JJ cord-005646-xhx9pzhj 537 37 vital vital JJ cord-005646-xhx9pzhj 537 38 functions function NNS cord-005646-xhx9pzhj 537 39 , , , cord-005646-xhx9pzhj 537 40 connected connect VBN cord-005646-xhx9pzhj 537 41 with with IN cord-005646-xhx9pzhj 537 42 the the DT cord-005646-xhx9pzhj 537 43 trauma trauma NN cord-005646-xhx9pzhj 537 44 , , , cord-005646-xhx9pzhj 537 45 and and CC cord-005646-xhx9pzhj 537 46 most most RBS cord-005646-xhx9pzhj 537 47 often often RB cord-005646-xhx9pzhj 537 48 with with IN cord-005646-xhx9pzhj 537 49 massive massive JJ cord-005646-xhx9pzhj 537 50 haemorrhage haemorrhage NN cord-005646-xhx9pzhj 537 51 , , , cord-005646-xhx9pzhj 537 52 for for IN cord-005646-xhx9pzhj 537 53 this this DT cord-005646-xhx9pzhj 537 54 reason reason NN cord-005646-xhx9pzhj 537 55 being be VBG cord-005646-xhx9pzhj 537 56 an an DT cord-005646-xhx9pzhj 537 57 object object NN cord-005646-xhx9pzhj 537 58 of of IN cord-005646-xhx9pzhj 537 59 reanimation reanimation NN cord-005646-xhx9pzhj 537 60 and and CC cord-005646-xhx9pzhj 537 61 intensive intensive JJ cord-005646-xhx9pzhj 537 62 care care NN cord-005646-xhx9pzhj 537 63 . . . cord-005646-xhx9pzhj 538 1 In in IN cord-005646-xhx9pzhj 538 2 the the DT cord-005646-xhx9pzhj 538 3 group group NN cord-005646-xhx9pzhj 538 4 of of IN cord-005646-xhx9pzhj 538 5 children child NNS cord-005646-xhx9pzhj 538 6 who who WP cord-005646-xhx9pzhj 538 7 survived survive VBD cord-005646-xhx9pzhj 538 8 -37 -37 NNP cord-005646-xhx9pzhj 538 9 , , , cord-005646-xhx9pzhj 538 10 predominated predominate VBD cord-005646-xhx9pzhj 538 11 the the DT cord-005646-xhx9pzhj 538 12 trauma trauma NN cord-005646-xhx9pzhj 538 13 of of IN cord-005646-xhx9pzhj 538 14 only only RB cord-005646-xhx9pzhj 538 15 one one CD cord-005646-xhx9pzhj 538 16 abdominal abdominal JJ cord-005646-xhx9pzhj 538 17 organ organ NN cord-005646-xhx9pzhj 538 18 ( ( -LRB- cord-005646-xhx9pzhj 538 19 mainly mainly RB cord-005646-xhx9pzhj 538 20 the the DT cord-005646-xhx9pzhj 538 21 spleen spleen NN cord-005646-xhx9pzhj 538 22 , , , cord-005646-xhx9pzhj 538 23 rarely rarely RB cord-005646-xhx9pzhj 538 24 the the DT cord-005646-xhx9pzhj 538 25 kidneys kidney NNS cord-005646-xhx9pzhj 538 26 , , , cord-005646-xhx9pzhj 538 27 the the DT cord-005646-xhx9pzhj 538 28 intestine intestine NN cord-005646-xhx9pzhj 538 29 ) ) -RRB- cord-005646-xhx9pzhj 538 30 and and CC cord-005646-xhx9pzhj 538 31 only only RB cord-005646-xhx9pzhj 538 32 15 15 CD cord-005646-xhx9pzhj 538 33 children child NNS cord-005646-xhx9pzhj 538 34 had have VBD cord-005646-xhx9pzhj 538 35 injuries injury NNS cord-005646-xhx9pzhj 538 36 of of IN cord-005646-xhx9pzhj 538 37 more more JJR cord-005646-xhx9pzhj 538 38 than than IN cord-005646-xhx9pzhj 538 39 one one CD cord-005646-xhx9pzhj 538 40 abdominal abdominal JJ cord-005646-xhx9pzhj 538 41 organ organ NN cord-005646-xhx9pzhj 538 42 . . . cord-005646-xhx9pzhj 539 1 In in IN cord-005646-xhx9pzhj 539 2 the the DT cord-005646-xhx9pzhj 539 3 same same JJ cord-005646-xhx9pzhj 539 4 group group NN cord-005646-xhx9pzhj 539 5 , , , cord-005646-xhx9pzhj 539 6 in in IN cord-005646-xhx9pzhj 539 7 15 15 CD cord-005646-xhx9pzhj 539 8 children child NNS cord-005646-xhx9pzhj 539 9 the the DT cord-005646-xhx9pzhj 539 10 abdominal abdominal JJ cord-005646-xhx9pzhj 539 11 trauma trauma NN cord-005646-xhx9pzhj 539 12 was be VBD cord-005646-xhx9pzhj 539 13 combined combine VBN cord-005646-xhx9pzhj 539 14 with with IN cord-005646-xhx9pzhj 539 15 chest chest NN cord-005646-xhx9pzhj 539 16 or or CC cord-005646-xhx9pzhj 539 17 head head NN cord-005646-xhx9pzhj 539 18 trauma trauma NN cord-005646-xhx9pzhj 539 19 or or CC cord-005646-xhx9pzhj 539 20 bone bone NN cord-005646-xhx9pzhj 539 21 fractures fracture NNS cord-005646-xhx9pzhj 539 22 . . . cord-005646-xhx9pzhj 540 1 In in IN cord-005646-xhx9pzhj 540 2 the the DT cord-005646-xhx9pzhj 540 3 group group NN cord-005646-xhx9pzhj 540 4 of of IN cord-005646-xhx9pzhj 540 5 children child NNS cord-005646-xhx9pzhj 540 6 who who WP cord-005646-xhx9pzhj 540 7 died die VBD cord-005646-xhx9pzhj 540 8 -12 -12 CD cord-005646-xhx9pzhj 540 9 , , , cord-005646-xhx9pzhj 540 10 a a DT cord-005646-xhx9pzhj 540 11 profound profound JJ cord-005646-xhx9pzhj 540 12 combined combined JJ cord-005646-xhx9pzhj 540 13 trauma trauma NN cord-005646-xhx9pzhj 540 14 was be VBD cord-005646-xhx9pzhj 540 15 present present JJ cord-005646-xhx9pzhj 540 16 . . . cord-005646-xhx9pzhj 541 1 The the DT cord-005646-xhx9pzhj 541 2 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 541 3 parameters parameter NNS cord-005646-xhx9pzhj 541 4 in in IN cord-005646-xhx9pzhj 541 5 all all DT cord-005646-xhx9pzhj 541 6 children child NNS cord-005646-xhx9pzhj 541 7 showed show VBD cord-005646-xhx9pzhj 541 8 a a DT cord-005646-xhx9pzhj 541 9 characteristically characteristically RB cord-005646-xhx9pzhj 541 10 significant significant JJ cord-005646-xhx9pzhj 541 11 tachycardia tachycardia NN cord-005646-xhx9pzhj 541 12 along along IN cord-005646-xhx9pzhj 541 13 with with IN cord-005646-xhx9pzhj 541 14 normal normal JJ cord-005646-xhx9pzhj 541 15 or or CC cord-005646-xhx9pzhj 541 16 even even RB cord-005646-xhx9pzhj 541 17 high high JJ cord-005646-xhx9pzhj 541 18 blood blood NN cord-005646-xhx9pzhj 541 19 pressure pressure NN cord-005646-xhx9pzhj 541 20 , , , cord-005646-xhx9pzhj 541 21 while while IN cord-005646-xhx9pzhj 541 22 hypotonia hypotonia NNS cord-005646-xhx9pzhj 541 23 was be VBD cord-005646-xhx9pzhj 541 24 present present JJ cord-005646-xhx9pzhj 541 25 in in IN cord-005646-xhx9pzhj 541 26 only only RB cord-005646-xhx9pzhj 541 27 64 64 CD cord-005646-xhx9pzhj 541 28 % % NN cord-005646-xhx9pzhj 541 29 of of IN cord-005646-xhx9pzhj 541 30 the the DT cord-005646-xhx9pzhj 541 31 children child NNS cord-005646-xhx9pzhj 541 32 on on IN cord-005646-xhx9pzhj 541 33 the the DT cord-005646-xhx9pzhj 541 34 first first JJ cord-005646-xhx9pzhj 541 35 trauma trauma NN cord-005646-xhx9pzhj 541 36 day day NN cord-005646-xhx9pzhj 541 37 . . . cord-005646-xhx9pzhj 542 1 Despite despite IN cord-005646-xhx9pzhj 542 2 the the DT cord-005646-xhx9pzhj 542 3 fact fact NN cord-005646-xhx9pzhj 542 4 that that IN cord-005646-xhx9pzhj 542 5 only only RB cord-005646-xhx9pzhj 542 6 13.4 13.4 CD cord-005646-xhx9pzhj 542 7 % % NN cord-005646-xhx9pzhj 542 8 of of IN cord-005646-xhx9pzhj 542 9 the the DT cord-005646-xhx9pzhj 542 10 children child NNS cord-005646-xhx9pzhj 542 11 had have VBD cord-005646-xhx9pzhj 542 12 direct direct JJ cord-005646-xhx9pzhj 542 13 chest chest NN cord-005646-xhx9pzhj 542 14 injury injury NN cord-005646-xhx9pzhj 542 15 as as RB cord-005646-xhx9pzhj 542 16 well well RB cord-005646-xhx9pzhj 542 17 , , , cord-005646-xhx9pzhj 542 18 the the DT cord-005646-xhx9pzhj 542 19 gas gas NN cord-005646-xhx9pzhj 542 20 exchange exchange NN cord-005646-xhx9pzhj 542 21 was be VBD cord-005646-xhx9pzhj 542 22 considerably considerably RB cord-005646-xhx9pzhj 542 23 disturbed disturb VBN cord-005646-xhx9pzhj 542 24 -899'0 -899'0 NN cord-005646-xhx9pzhj 542 25 of of IN cord-005646-xhx9pzhj 542 26 the the DT cord-005646-xhx9pzhj 542 27 children child NNS cord-005646-xhx9pzhj 542 28 were be VBD cord-005646-xhx9pzhj 542 29 hypoxemic hypoxemic JJ cord-005646-xhx9pzhj 542 30 during during IN cord-005646-xhx9pzhj 542 31 the the DT cord-005646-xhx9pzhj 542 32 first first JJ cord-005646-xhx9pzhj 542 33 , , , cord-005646-xhx9pzhj 542 34 and and CC cord-005646-xhx9pzhj 542 35 100 100 CD cord-005646-xhx9pzhj 542 36 % % NN cord-005646-xhx9pzhj 542 37 during during IN cord-005646-xhx9pzhj 542 38 the the DT cord-005646-xhx9pzhj 542 39 third third JJ cord-005646-xhx9pzhj 542 40 trauma trauma NN cord-005646-xhx9pzhj 542 41 day day NN cord-005646-xhx9pzhj 542 42 -in -in CD cord-005646-xhx9pzhj 542 43 25 25 CD cord-005646-xhx9pzhj 542 44 % % NN cord-005646-xhx9pzhj 542 45 significant significant JJ cord-005646-xhx9pzhj 542 46 -below -below . cord-005646-xhx9pzhj 543 1 8.0 8.0 CD cord-005646-xhx9pzhj 543 2 kPa kPa NNS cord-005646-xhx9pzhj 543 3 ( ( -LRB- cord-005646-xhx9pzhj 543 4 60 60 CD cord-005646-xhx9pzhj 543 5 mmHg mmHg NNS cord-005646-xhx9pzhj 543 6 ) ) -RRB- cord-005646-xhx9pzhj 543 7 . . . cord-005646-xhx9pzhj 544 1 Together together RB cord-005646-xhx9pzhj 544 2 with with IN cord-005646-xhx9pzhj 544 3 the the DT cord-005646-xhx9pzhj 544 4 markable markable JJ cord-005646-xhx9pzhj 544 5 decrease decrease NN cord-005646-xhx9pzhj 544 6 in in IN cord-005646-xhx9pzhj 544 7 haemoglobin haemoglobin NN cord-005646-xhx9pzhj 544 8 levels level NNS cord-005646-xhx9pzhj 544 9 , , , cord-005646-xhx9pzhj 544 10 this this DT cord-005646-xhx9pzhj 544 11 determines determine VBZ cord-005646-xhx9pzhj 544 12 the the DT cord-005646-xhx9pzhj 544 13 pronounced pronounced JJ cord-005646-xhx9pzhj 544 14 disturbance disturbance NN cord-005646-xhx9pzhj 544 15 in in IN cord-005646-xhx9pzhj 544 16 oxygen oxygen NN cord-005646-xhx9pzhj 544 17 transport transport NN cord-005646-xhx9pzhj 544 18 . . . cord-005646-xhx9pzhj 545 1 During during IN cord-005646-xhx9pzhj 545 2 the the DT cord-005646-xhx9pzhj 545 3 first first JJ cord-005646-xhx9pzhj 545 4 trauma trauma NN cord-005646-xhx9pzhj 545 5 day day NN cord-005646-xhx9pzhj 545 6 all all PDT cord-005646-xhx9pzhj 545 7 the the DT cord-005646-xhx9pzhj 545 8 children child NNS cord-005646-xhx9pzhj 545 9 were be VBD cord-005646-xhx9pzhj 545 10 acldo acldo NNP cord-005646-xhx9pzhj 545 11 ~ ~ NFP cord-005646-xhx9pzhj 545 12 c c NNP cord-005646-xhx9pzhj 545 13 , , , cord-005646-xhx9pzhj 545 14 and and CC cord-005646-xhx9pzhj 545 15 a a DT cord-005646-xhx9pzhj 545 16 metabolic metabolic JJ cord-005646-xhx9pzhj 545 17 alkalosis alkalosis NN cord-005646-xhx9pzhj 545 18 was be VBD cord-005646-xhx9pzhj 545 19 present present JJ cord-005646-xhx9pzhj 545 20 during during IN cord-005646-xhx9pzhj 545 21 the the DT cord-005646-xhx9pzhj 545 22 following follow VBG cord-005646-xhx9pzhj 545 23 days day NNS cord-005646-xhx9pzhj 545 24 . . . cord-005646-xhx9pzhj 546 1 Twelve twelve CD cord-005646-xhx9pzhj 546 2 of of IN cord-005646-xhx9pzhj 546 3 the the DT cord-005646-xhx9pzhj 546 4 children child NNS cord-005646-xhx9pzhj 546 5 with with IN cord-005646-xhx9pzhj 546 6 severe severe JJ cord-005646-xhx9pzhj 546 7 combined combine VBN cord-005646-xhx9pzhj 546 8 trauma trauma NN cord-005646-xhx9pzhj 546 9 died die VBD cord-005646-xhx9pzhj 546 10 within within IN cord-005646-xhx9pzhj 546 11 several several JJ cord-005646-xhx9pzhj 546 12 hours hour NNS cord-005646-xhx9pzhj 546 13 , , , cord-005646-xhx9pzhj 546 14 with with IN cord-005646-xhx9pzhj 546 15 the the DT cord-005646-xhx9pzhj 546 16 symptoms symptom NNS cord-005646-xhx9pzhj 546 17 of of IN cord-005646-xhx9pzhj 546 18 irreversible irreversible JJ cord-005646-xhx9pzhj 546 19 haemorrhagic haemorrhagic JJ cord-005646-xhx9pzhj 546 20 shock shock NN cord-005646-xhx9pzhj 546 21 , , , cord-005646-xhx9pzhj 546 22 or or CC cord-005646-xhx9pzhj 546 23 in in IN cord-005646-xhx9pzhj 546 24 the the DT cord-005646-xhx9pzhj 546 25 next next JJ cord-005646-xhx9pzhj 546 26 2 2 CD cord-005646-xhx9pzhj 546 27 - - SYM cord-005646-xhx9pzhj 546 28 3 3 CD cord-005646-xhx9pzhj 546 29 days day NNS cord-005646-xhx9pzhj 546 30 , , , cord-005646-xhx9pzhj 546 31 developing develop VBG cord-005646-xhx9pzhj 546 32 multiple multiple JJ cord-005646-xhx9pzhj 546 33 organ organ NN cord-005646-xhx9pzhj 546 34 failure failure NN cord-005646-xhx9pzhj 546 35 . . . cord-005646-xhx9pzhj 547 1 In in IN cord-005646-xhx9pzhj 547 2 conclusion conclusion NN cord-005646-xhx9pzhj 547 3 , , , cord-005646-xhx9pzhj 547 4 the the DT cord-005646-xhx9pzhj 547 5 intensive intensive JJ cord-005646-xhx9pzhj 547 6 therapy therapy NN cord-005646-xhx9pzhj 547 7 of of IN cord-005646-xhx9pzhj 547 8 children child NNS cord-005646-xhx9pzhj 547 9 with with IN cord-005646-xhx9pzhj 547 10 severe severe JJ cord-005646-xhx9pzhj 547 11 abdominal abdominal JJ cord-005646-xhx9pzhj 547 12 and and CC cord-005646-xhx9pzhj 547 13 combined combined JJ cord-005646-xhx9pzhj 547 14 trauma trauma NN cord-005646-xhx9pzhj 547 15 , , , cord-005646-xhx9pzhj 547 16 should should MD cord-005646-xhx9pzhj 547 17 take take VB cord-005646-xhx9pzhj 547 18 in in IN cord-005646-xhx9pzhj 547 19 consideration consideration NN cord-005646-xhx9pzhj 547 20 the the DT cord-005646-xhx9pzhj 547 21 special special JJ cord-005646-xhx9pzhj 547 22 haemodynamical haemodynamical JJ cord-005646-xhx9pzhj 547 23 trauma trauma NN cord-005646-xhx9pzhj 547 24 answer answer NN cord-005646-xhx9pzhj 547 25 in in IN cord-005646-xhx9pzhj 547 26 children child NNS cord-005646-xhx9pzhj 547 27 , , , cord-005646-xhx9pzhj 547 28 and and CC cord-005646-xhx9pzhj 547 29 requires require VBZ cord-005646-xhx9pzhj 547 30 dynamic dynamic JJ cord-005646-xhx9pzhj 547 31 monitoring monitoring NN cord-005646-xhx9pzhj 547 32 of of IN cord-005646-xhx9pzhj 547 33 the the DT cord-005646-xhx9pzhj 547 34 most most RBS cord-005646-xhx9pzhj 547 35 influenced influence VBN cord-005646-xhx9pzhj 547 36 homeostatic homeostatic JJ cord-005646-xhx9pzhj 547 37 parameters parameter NNS cord-005646-xhx9pzhj 547 38 -blood -blood SYM cord-005646-xhx9pzhj 547 39 gases gas NNS cord-005646-xhx9pzhj 547 40 , , , cord-005646-xhx9pzhj 547 41 acid acid NN cord-005646-xhx9pzhj 547 42 - - HYPH cord-005646-xhx9pzhj 547 43 base base NN cord-005646-xhx9pzhj 547 44 metabolism metabolism NN cord-005646-xhx9pzhj 547 45 , , , cord-005646-xhx9pzhj 547 46 haemostasis haemostasis NN cord-005646-xhx9pzhj 547 47 . . . cord-005646-xhx9pzhj 548 1 Introduction introduction NN cord-005646-xhx9pzhj 548 2 : : : cord-005646-xhx9pzhj 548 3 Endocrine endocrine JJ cord-005646-xhx9pzhj 548 4 emergencies emergency NNS cord-005646-xhx9pzhj 548 5 , , , cord-005646-xhx9pzhj 548 6 other other JJ cord-005646-xhx9pzhj 548 7 than than IN cord-005646-xhx9pzhj 548 8 diabetic diabetic JJ cord-005646-xhx9pzhj 548 9 ketoacidosis ketoacidosis NN cord-005646-xhx9pzhj 548 10 , , , cord-005646-xhx9pzhj 548 11 are be VBP cord-005646-xhx9pzhj 548 12 uncommon uncommon JJ cord-005646-xhx9pzhj 548 13 causes cause NNS cord-005646-xhx9pzhj 548 14 of of IN cord-005646-xhx9pzhj 548 15 Pediatric Pediatric NNP cord-005646-xhx9pzhj 548 16 Intensive Intensive NNP cord-005646-xhx9pzhj 548 17 Care Care NNP cord-005646-xhx9pzhj 548 18 Unit Unit NNP cord-005646-xhx9pzhj 548 19 ( ( -LRB- cord-005646-xhx9pzhj 548 20 PICU PICU NNP cord-005646-xhx9pzhj 548 21 ) ) -RRB- cord-005646-xhx9pzhj 548 22 admissions admission NNS cord-005646-xhx9pzhj 548 23 . . . cord-005646-xhx9pzhj 549 1 We -PRON- PRP cord-005646-xhx9pzhj 549 2 report report VBP cord-005646-xhx9pzhj 549 3 our -PRON- PRP$ cord-005646-xhx9pzhj 549 4 experience experience NN cord-005646-xhx9pzhj 549 5 of of IN cord-005646-xhx9pzhj 549 6 children child NNS cord-005646-xhx9pzhj 549 7 diagnosed diagnose VBN cord-005646-xhx9pzhj 549 8 of of IN cord-005646-xhx9pzhj 549 9 adrenal adrenal JJ cord-005646-xhx9pzhj 549 10 insuficiency insuficiency NN cord-005646-xhx9pzhj 549 11 ( ( -LRB- cord-005646-xhx9pzhj 549 12 AI AI NNP cord-005646-xhx9pzhj 549 13 ) ) -RRB- cord-005646-xhx9pzhj 549 14 admitted admit VBN cord-005646-xhx9pzhj 549 15 in in IN cord-005646-xhx9pzhj 549 16 the the DT cord-005646-xhx9pzhj 549 17 PICU PICU NNP cord-005646-xhx9pzhj 549 18 , , , cord-005646-xhx9pzhj 549 19 during during IN cord-005646-xhx9pzhj 549 20 the the DT cord-005646-xhx9pzhj 549 21 last last JJ cord-005646-xhx9pzhj 549 22 four four CD cord-005646-xhx9pzhj 549 23 years year NNS cord-005646-xhx9pzhj 549 24 . . . cord-005646-xhx9pzhj 550 1 Subjects subject NNS cord-005646-xhx9pzhj 550 2 : : : cord-005646-xhx9pzhj 551 1 Five five CD cord-005646-xhx9pzhj 551 2 eases ease NNS cord-005646-xhx9pzhj 551 3 of of IN cord-005646-xhx9pzhj 551 4 AI AI NNP cord-005646-xhx9pzhj 551 5 requiring require VBG cord-005646-xhx9pzhj 551 6 7 7 CD cord-005646-xhx9pzhj 551 7 intensive intensive JJ cord-005646-xhx9pzhj 551 8 care care NN cord-005646-xhx9pzhj 551 9 unit unit NN cord-005646-xhx9pzhj 551 10 admissions admission NNS cord-005646-xhx9pzhj 551 11 are be VBP cord-005646-xhx9pzhj 551 12 presented present VBN cord-005646-xhx9pzhj 551 13 . . . cord-005646-xhx9pzhj 552 1 Four four CD cord-005646-xhx9pzhj 552 2 females female NNS cord-005646-xhx9pzhj 552 3 anna anna NNP cord-005646-xhx9pzhj 552 4 1 1 CD cord-005646-xhx9pzhj 552 5 male male NN cord-005646-xhx9pzhj 552 6 , , , cord-005646-xhx9pzhj 552 7 with with IN cord-005646-xhx9pzhj 552 8 ages age NNS cord-005646-xhx9pzhj 552 9 ranging range VBG cord-005646-xhx9pzhj 552 10 from from IN cord-005646-xhx9pzhj 552 11 11 11 CD cord-005646-xhx9pzhj 552 12 days day NNS cord-005646-xhx9pzhj 552 13 to to IN cord-005646-xhx9pzhj 552 14 7 7 CD cord-005646-xhx9pzhj 552 15 years year NNS cord-005646-xhx9pzhj 552 16 , , , cord-005646-xhx9pzhj 552 17 None none NN cord-005646-xhx9pzhj 552 18 of of IN cord-005646-xhx9pzhj 552 19 them -PRON- PRP cord-005646-xhx9pzhj 552 20 had have VBD cord-005646-xhx9pzhj 552 21 a a DT cord-005646-xhx9pzhj 552 22 previous previous JJ cord-005646-xhx9pzhj 552 23 systemic systemic JJ cord-005646-xhx9pzhj 552 24 or or CC cord-005646-xhx9pzhj 552 25 endocrine endocrine JJ cord-005646-xhx9pzhj 552 26 diseases disease NNS cord-005646-xhx9pzhj 552 27 that that WDT cord-005646-xhx9pzhj 552 28 could could MD cord-005646-xhx9pzhj 552 29 suggest suggest VB cord-005646-xhx9pzhj 552 30 AL AL NNP cord-005646-xhx9pzhj 553 1 The the DT cord-005646-xhx9pzhj 553 2 initial initial JJ cord-005646-xhx9pzhj 553 3 clinical clinical JJ cord-005646-xhx9pzhj 553 4 manifestations manifestation NNS cord-005646-xhx9pzhj 553 5 were be VBD cord-005646-xhx9pzhj 553 6 : : : cord-005646-xhx9pzhj 553 7 dehydration dehydration NN cord-005646-xhx9pzhj 553 8 ( ( -LRB- cord-005646-xhx9pzhj 553 9 5 5 CD cord-005646-xhx9pzhj 553 10 ) ) -RRB- cord-005646-xhx9pzhj 553 11 , , , cord-005646-xhx9pzhj 553 12 vomits vomit VBZ cord-005646-xhx9pzhj 553 13 ( ( -LRB- cord-005646-xhx9pzhj 553 14 3 3 CD cord-005646-xhx9pzhj 553 15 ) ) -RRB- cord-005646-xhx9pzhj 553 16 , , , cord-005646-xhx9pzhj 553 17 abdominal abdominal JJ cord-005646-xhx9pzhj 553 18 pain pain NN cord-005646-xhx9pzhj 553 19 ( ( -LRB- cord-005646-xhx9pzhj 553 20 2 2 CD cord-005646-xhx9pzhj 553 21 ) ) -RRB- cord-005646-xhx9pzhj 553 22 , , , cord-005646-xhx9pzhj 553 23 seizures seizure NNS cord-005646-xhx9pzhj 553 24 ( ( -LRB- cord-005646-xhx9pzhj 553 25 2 2 CD cord-005646-xhx9pzhj 553 26 ) ) -RRB- cord-005646-xhx9pzhj 553 27 , , , cord-005646-xhx9pzhj 553 28 lethargy lethargy NN cord-005646-xhx9pzhj 553 29 ( ( -LRB- cord-005646-xhx9pzhj 553 30 2 2 CD cord-005646-xhx9pzhj 553 31 ) ) -RRB- cord-005646-xhx9pzhj 553 32 and and CC cord-005646-xhx9pzhj 553 33 hyperpigmentation hyperpigmentation NN cord-005646-xhx9pzhj 553 34 in in IN cord-005646-xhx9pzhj 553 35 the the DT cord-005646-xhx9pzhj 553 36 muco muco JJ cord-005646-xhx9pzhj 553 37 - - HYPH cord-005646-xhx9pzhj 553 38 genitat genitat JJ cord-005646-xhx9pzhj 553 39 area area NN cord-005646-xhx9pzhj 553 40 in in IN cord-005646-xhx9pzhj 553 41 a a DT cord-005646-xhx9pzhj 553 42 newborn newborn JJ cord-005646-xhx9pzhj 553 43 male male NN cord-005646-xhx9pzhj 553 44 and and CC cord-005646-xhx9pzhj 553 45 ambigna ambigna VBP cord-005646-xhx9pzhj 553 46 genitalia genitalia NNS cord-005646-xhx9pzhj 553 47 in in IN cord-005646-xhx9pzhj 553 48 a a DT cord-005646-xhx9pzhj 553 49 newborn newborn JJ cord-005646-xhx9pzhj 553 50 female female NN cord-005646-xhx9pzhj 553 51 . . . cord-005646-xhx9pzhj 554 1 The the DT cord-005646-xhx9pzhj 554 2 reason reason NN cord-005646-xhx9pzhj 554 3 for for IN cord-005646-xhx9pzhj 554 4 their -PRON- PRP$ cord-005646-xhx9pzhj 554 5 admission admission NN cord-005646-xhx9pzhj 554 6 in in IN cord-005646-xhx9pzhj 554 7 the the DT cord-005646-xhx9pzhj 554 8 P1CU P1CU NNP cord-005646-xhx9pzhj 554 9 were be VBD cord-005646-xhx9pzhj 554 10 : : : cord-005646-xhx9pzhj 554 11 shock shock NN cord-005646-xhx9pzhj 554 12 in in IN cord-005646-xhx9pzhj 554 13 two two CD cord-005646-xhx9pzhj 554 14 subjects subject NNS cord-005646-xhx9pzhj 554 15 ; ; : cord-005646-xhx9pzhj 554 16 three three CD cord-005646-xhx9pzhj 554 17 because because IN cord-005646-xhx9pzhj 554 18 of of IN cord-005646-xhx9pzhj 554 19 hyperkalemia hyperkalemia NN cord-005646-xhx9pzhj 554 20 and and CC cord-005646-xhx9pzhj 554 21 hyponatremia hyponatremia NN cord-005646-xhx9pzhj 554 22 ( ( -LRB- cord-005646-xhx9pzhj 554 23 K K NNP cord-005646-xhx9pzhj 554 24 / / SYM cord-005646-xhx9pzhj 554 25 Na Na NNP cord-005646-xhx9pzhj 554 26 : : : cord-005646-xhx9pzhj 554 27 5.6/123 5.6/123 CD cord-005646-xhx9pzhj 554 28 ; ; : cord-005646-xhx9pzhj 554 29 9/126 9/126 CD cord-005646-xhx9pzhj 554 30 ; ; : cord-005646-xhx9pzhj 554 31 7,1/134 7,1/134 CD cord-005646-xhx9pzhj 554 32 mEq mEq NNS cord-005646-xhx9pzhj 554 33 / / SYM cord-005646-xhx9pzhj 554 34 L L NNP cord-005646-xhx9pzhj 554 35 ) ) -RRB- cord-005646-xhx9pzhj 554 36 ; ; : cord-005646-xhx9pzhj 554 37 and and CC cord-005646-xhx9pzhj 554 38 two two CD cord-005646-xhx9pzhj 554 39 with with IN cord-005646-xhx9pzhj 554 40 severe severe JJ cord-005646-xhx9pzhj 554 41 hyponatremia hyponatremia NN cord-005646-xhx9pzhj 555 1 ( ( -LRB- cord-005646-xhx9pzhj 555 2 Na Na NNP cord-005646-xhx9pzhj 555 3 : : : cord-005646-xhx9pzhj 555 4 117 117 CD cord-005646-xhx9pzhj 555 5 ; ; : cord-005646-xhx9pzhj 555 6 113 113 CD cord-005646-xhx9pzhj 555 7 mEq mEq NNS cord-005646-xhx9pzhj 555 8 / / SYM cord-005646-xhx9pzhj 555 9 L L NNP cord-005646-xhx9pzhj 555 10 ) ) -RRB- cord-005646-xhx9pzhj 555 11 . . . cord-005646-xhx9pzhj 556 1 Laboratory laboratory NN cord-005646-xhx9pzhj 556 2 findings finding NNS cord-005646-xhx9pzhj 556 3 : : : cord-005646-xhx9pzhj 556 4 severe severe JJ cord-005646-xhx9pzhj 556 5 hyponatremia hyponatremia NN cord-005646-xhx9pzhj 556 6 ( ( -LRB- cord-005646-xhx9pzhj 556 7 5 5 CD cord-005646-xhx9pzhj 556 8 ) ) -RRB- cord-005646-xhx9pzhj 556 9 , , , cord-005646-xhx9pzhj 556 10 increased increase VBN cord-005646-xhx9pzhj 556 11 concentration concentration NN cord-005646-xhx9pzhj 556 12 of of IN cord-005646-xhx9pzhj 556 13 urinary urinary JJ cord-005646-xhx9pzhj 556 14 sodium sodium NN cord-005646-xhx9pzhj 556 15 and and CC cord-005646-xhx9pzhj 556 16 chloride chloride NN cord-005646-xhx9pzhj 556 17 ( ( -LRB- cord-005646-xhx9pzhj 556 18 4 4 CD cord-005646-xhx9pzhj 556 19 ) ) -RRB- cord-005646-xhx9pzhj 556 20 ; ; : cord-005646-xhx9pzhj 556 21 metabolic metabolic JJ cord-005646-xhx9pzhj 556 22 acidosis acidosis NN cord-005646-xhx9pzhj 556 23 ( ( -LRB- cord-005646-xhx9pzhj 556 24 4 4 CD cord-005646-xhx9pzhj 556 25 ) ) -RRB- cord-005646-xhx9pzhj 556 26 ; ; : cord-005646-xhx9pzhj 556 27 hyperkalemia hyperkalemia NN cord-005646-xhx9pzhj 556 28 ( ( -LRB- cord-005646-xhx9pzhj 556 29 3 3 CD cord-005646-xhx9pzhj 556 30 ) ) -RRB- cord-005646-xhx9pzhj 556 31 ; ; : cord-005646-xhx9pzhj 556 32 increased increase VBN cord-005646-xhx9pzhj 556 33 levels level NNS cord-005646-xhx9pzhj 556 34 of of IN cord-005646-xhx9pzhj 556 35 urea urea NN cord-005646-xhx9pzhj 556 36 ( ( -LRB- cord-005646-xhx9pzhj 556 37 3 3 CD cord-005646-xhx9pzhj 556 38 ) ) -RRB- cord-005646-xhx9pzhj 556 39 and and CC cord-005646-xhx9pzhj 556 40 hypoglycemia hypoglycemia NN cord-005646-xhx9pzhj 556 41 ( ( -LRB- cord-005646-xhx9pzhj 556 42 2 2 CD cord-005646-xhx9pzhj 556 43 ) ) -RRB- cord-005646-xhx9pzhj 556 44 . . . cord-005646-xhx9pzhj 557 1 In in IN cord-005646-xhx9pzhj 557 2 all all DT cord-005646-xhx9pzhj 557 3 of of IN cord-005646-xhx9pzhj 557 4 them -PRON- PRP cord-005646-xhx9pzhj 557 5 , , , cord-005646-xhx9pzhj 557 6 the the DT cord-005646-xhx9pzhj 557 7 electrolytes electrolyte NNS cord-005646-xhx9pzhj 557 8 abnormalities abnormality NNS cord-005646-xhx9pzhj 557 9 did do VBD cord-005646-xhx9pzhj 557 10 not not RB cord-005646-xhx9pzhj 557 11 normalize normalize VB cord-005646-xhx9pzhj 557 12 with with IN cord-005646-xhx9pzhj 557 13 replacement replacement NN cord-005646-xhx9pzhj 557 14 and and CC cord-005646-xhx9pzhj 557 15 only only RB cord-005646-xhx9pzhj 557 16 normalized normalize VBN cord-005646-xhx9pzhj 557 17 after after IN cord-005646-xhx9pzhj 557 18 the the DT cord-005646-xhx9pzhj 557 19 administration administration NN cord-005646-xhx9pzhj 557 20 of of IN cord-005646-xhx9pzhj 557 21 hydrocortisone hydrocortisone NNP cord-005646-xhx9pzhj 557 22 . . . cord-005646-xhx9pzhj 558 1 Tile Tile NNP cord-005646-xhx9pzhj 558 2 AI AI NNP cord-005646-xhx9pzhj 558 3 was be VBD cord-005646-xhx9pzhj 558 4 due due JJ cord-005646-xhx9pzhj 558 5 to to IN cord-005646-xhx9pzhj 558 6 : : : cord-005646-xhx9pzhj 558 7 autoimmtme autoimmtme NNP cord-005646-xhx9pzhj 558 8 disease disease NNP cord-005646-xhx9pzhj 558 9 in in IN cord-005646-xhx9pzhj 558 10 two two CD cord-005646-xhx9pzhj 558 11 subjects subject NNS cord-005646-xhx9pzhj 558 12 , , , cord-005646-xhx9pzhj 558 13 congenital congenital JJ cord-005646-xhx9pzhj 558 14 adrenal adrenal JJ cord-005646-xhx9pzhj 558 15 hypoplasia hypoplasia NN cord-005646-xhx9pzhj 558 16 , , , cord-005646-xhx9pzhj 558 17 congenital congenital JJ cord-005646-xhx9pzhj 558 18 adrenal adrenal JJ cord-005646-xhx9pzhj 558 19 hyperplasia hyperplasia NN cord-005646-xhx9pzhj 558 20 secondary secondary JJ cord-005646-xhx9pzhj 558 21 to to IN cord-005646-xhx9pzhj 558 22 21 21 CD cord-005646-xhx9pzhj 558 23 alia alia NNP cord-005646-xhx9pzhj 558 24 hydroxylase hydroxylase NNP cord-005646-xhx9pzhj 558 25 deficiency deficiency NN cord-005646-xhx9pzhj 558 26 and and CC cord-005646-xhx9pzhj 558 27 in in IN cord-005646-xhx9pzhj 558 28 one one CD cord-005646-xhx9pzhj 558 29 no no DT cord-005646-xhx9pzhj 558 30 etiology etiology NN cord-005646-xhx9pzhj 558 31 was be VBD cord-005646-xhx9pzhj 558 32 found find VBN cord-005646-xhx9pzhj 558 33 , , , cord-005646-xhx9pzhj 558 34 at at IN cord-005646-xhx9pzhj 558 35 the the DT cord-005646-xhx9pzhj 558 36 present present JJ cord-005646-xhx9pzhj 558 37 time time NN cord-005646-xhx9pzhj 558 38 , , , cord-005646-xhx9pzhj 559 1 Comments comment NNS cord-005646-xhx9pzhj 559 2 : : : cord-005646-xhx9pzhj 559 3 AIis AIis NNP cord-005646-xhx9pzhj 559 4 an an DT cord-005646-xhx9pzhj 559 5 uncommon uncommon JJ cord-005646-xhx9pzhj 559 6 disease disease NN cord-005646-xhx9pzhj 559 7 in in IN cord-005646-xhx9pzhj 559 8 the the DT cord-005646-xhx9pzhj 559 9 pediatric pediatric JJ cord-005646-xhx9pzhj 559 10 age age NN cord-005646-xhx9pzhj 559 11 . . . cord-005646-xhx9pzhj 560 1 Anearly Anearly NNP cord-005646-xhx9pzhj 560 2 diagnosis diagnosis NN cord-005646-xhx9pzhj 560 3 is be VBZ cord-005646-xhx9pzhj 560 4 crucial crucial JJ cord-005646-xhx9pzhj 560 5 , , , cord-005646-xhx9pzhj 560 6 as as IN cord-005646-xhx9pzhj 560 7 if if IN cord-005646-xhx9pzhj 560 8 the the DT cord-005646-xhx9pzhj 560 9 treatment treatment NN cord-005646-xhx9pzhj 560 10 is be VBZ cord-005646-xhx9pzhj 560 11 delayed delay VBN cord-005646-xhx9pzhj 560 12 could could MD cord-005646-xhx9pzhj 560 13 lead lead VB cord-005646-xhx9pzhj 560 14 to to IN cord-005646-xhx9pzhj 560 15 patients patient NNS cord-005646-xhx9pzhj 560 16 death death NN cord-005646-xhx9pzhj 560 17 . . . cord-005646-xhx9pzhj 561 1 In in IN cord-005646-xhx9pzhj 561 2 subjects subject NNS cord-005646-xhx9pzhj 561 3 with with IN cord-005646-xhx9pzhj 561 4 arterial arterial JJ cord-005646-xhx9pzhj 561 5 hypotension hypotension NN cord-005646-xhx9pzhj 561 6 and and CC cord-005646-xhx9pzhj 561 7 electrolytes electrolyte NNS cord-005646-xhx9pzhj 561 8 abnormalities abnormality NNS cord-005646-xhx9pzhj 561 9 refractory refractory JJ cord-005646-xhx9pzhj 561 10 to to IN cord-005646-xhx9pzhj 561 11 the the DT cord-005646-xhx9pzhj 561 12 usual usual JJ cord-005646-xhx9pzhj 561 13 treatment treatment NN cord-005646-xhx9pzhj 561 14 , , , cord-005646-xhx9pzhj 561 15 they -PRON- PRP cord-005646-xhx9pzhj 561 16 should should MD cord-005646-xhx9pzhj 561 17 be be VB cord-005646-xhx9pzhj 561 18 treated treat VBN cord-005646-xhx9pzhj 561 19 with with IN cord-005646-xhx9pzhj 561 20 corticosteroids corticosteroid NNS cord-005646-xhx9pzhj 561 21 , , , cord-005646-xhx9pzhj 561 22 if if IN cord-005646-xhx9pzhj 561 23 no no DT cord-005646-xhx9pzhj 561 24 etiology etiology NN cord-005646-xhx9pzhj 561 25 is be VBZ cord-005646-xhx9pzhj 561 26 found find VBN cord-005646-xhx9pzhj 561 27 . . . cord-005646-xhx9pzhj 562 1 Although although IN cord-005646-xhx9pzhj 562 2 , , , cord-005646-xhx9pzhj 562 3 previously previously RB cord-005646-xhx9pzhj 562 4 samples sample NNS cord-005646-xhx9pzhj 562 5 must must MD cord-005646-xhx9pzhj 562 6 be be VB cord-005646-xhx9pzhj 562 7 obtained obtain VBN cord-005646-xhx9pzhj 562 8 to to TO cord-005646-xhx9pzhj 562 9 make make VB cord-005646-xhx9pzhj 562 10 the the DT cord-005646-xhx9pzhj 562 11 diagnosis diagnosis NN cord-005646-xhx9pzhj 562 12 , , , cord-005646-xhx9pzhj 562 13 0 0 CD cord-005646-xhx9pzhj 562 14 : : : cord-005646-xhx9pzhj 562 15 denotes denote VBZ cord-005646-xhx9pzhj 562 16 the the DT cord-005646-xhx9pzhj 562 17 number number NN cord-005646-xhx9pzhj 562 18 of of IN cord-005646-xhx9pzhj 562 19 cases case NNS cord-005646-xhx9pzhj 562 20 . . . cord-005646-xhx9pzhj 563 1 GERBAKA GERBAKA NNP cord-005646-xhx9pzhj 563 2 B B NNP cord-005646-xhx9pzhj 563 3 ; ; : cord-005646-xhx9pzhj 563 4 HAKME HAKME NNP cord-005646-xhx9pzhj 563 5 C C NNP cord-005646-xhx9pzhj 564 1 ; ; : cord-005646-xhx9pzhj 564 2 AKATCHERIAN AKATCHERIAN NNP cord-005646-xhx9pzhj 564 3 C. C. NNP cord-005646-xhx9pzhj 564 4 Toxics toxic NNS cord-005646-xhx9pzhj 564 5 are be VBP cord-005646-xhx9pzhj 564 6 frequently frequently RB cord-005646-xhx9pzhj 564 7 involved involve VBN cord-005646-xhx9pzhj 564 8 in in IN cord-005646-xhx9pzhj 564 9 domestic domestic JJ cord-005646-xhx9pzhj 564 10 accidents accident NNS cord-005646-xhx9pzhj 564 11 during during IN cord-005646-xhx9pzhj 564 12 childhood childhood NN cord-005646-xhx9pzhj 564 13 ; ; : cord-005646-xhx9pzhj 564 14 among among IN cord-005646-xhx9pzhj 564 15 non non JJ cord-005646-xhx9pzhj 564 16 medical medical JJ cord-005646-xhx9pzhj 564 17 products product NNS cord-005646-xhx9pzhj 564 18 ingestion ingestion NN cord-005646-xhx9pzhj 564 19 , , , cord-005646-xhx9pzhj 564 20 carbohydrate carbohydrate NN cord-005646-xhx9pzhj 564 21 poisoning poisoning NN cord-005646-xhx9pzhj 564 22 is be VBZ cord-005646-xhx9pzhj 564 23 a a DT cord-005646-xhx9pzhj 564 24 serious serious JJ cord-005646-xhx9pzhj 564 25 injury injury NN cord-005646-xhx9pzhj 564 26 often often RB cord-005646-xhx9pzhj 564 27 made make VBN cord-005646-xhx9pzhj 564 28 possible possible JJ cord-005646-xhx9pzhj 564 29 by by IN cord-005646-xhx9pzhj 564 30 inadequate inadequate JJ cord-005646-xhx9pzhj 564 31 stocking stocking NN cord-005646-xhx9pzhj 564 32 . . . cord-005646-xhx9pzhj 565 1 Over over IN cord-005646-xhx9pzhj 565 2 10 10 CD cord-005646-xhx9pzhj 565 3 years year NNS cord-005646-xhx9pzhj 565 4 , , , cord-005646-xhx9pzhj 565 5 43 43 CD cord-005646-xhx9pzhj 565 6 children child NNS cord-005646-xhx9pzhj 565 7 aged age VBN cord-005646-xhx9pzhj 565 8 10 10 CD cord-005646-xhx9pzhj 565 9 years year NNS cord-005646-xhx9pzhj 565 10 and and CC cord-005646-xhx9pzhj 565 11 less less JJR cord-005646-xhx9pzhj 565 12 were be VBD cord-005646-xhx9pzhj 565 13 examined examine VBN cord-005646-xhx9pzhj 565 14 in in IN cord-005646-xhx9pzhj 565 15 the the DT cord-005646-xhx9pzhj 565 16 emergency emergency NN cord-005646-xhx9pzhj 565 17 department department NN cord-005646-xhx9pzhj 565 18 of of IN cord-005646-xhx9pzhj 565 19 Hotel Hotel NNP cord-005646-xhx9pzhj 565 20 - - HYPH cord-005646-xhx9pzhj 565 21 Dieu Dieu NNP cord-005646-xhx9pzhj 565 22 de de FW cord-005646-xhx9pzhj 565 23 France France NNP cord-005646-xhx9pzhj 565 24 Hospital Hospital NNP cord-005646-xhx9pzhj 565 25 for for IN cord-005646-xhx9pzhj 565 26 carbohydrate carbohydrate NN cord-005646-xhx9pzhj 565 27 ingestion ingestion NN cord-005646-xhx9pzhj 565 28 . . . cord-005646-xhx9pzhj 566 1 62,8 62,8 CD cord-005646-xhx9pzhj 566 2 % % NN cord-005646-xhx9pzhj 566 3 are be VBP cord-005646-xhx9pzhj 566 4 boys boy NNS cord-005646-xhx9pzhj 566 5 ; ; : cord-005646-xhx9pzhj 566 6 age age NN cord-005646-xhx9pzhj 566 7 goes go VBZ cord-005646-xhx9pzhj 566 8 from from IN cord-005646-xhx9pzhj 566 9 13 13 CD cord-005646-xhx9pzhj 566 10 months month NNS cord-005646-xhx9pzhj 566 11 to to IN cord-005646-xhx9pzhj 566 12 6 6 CD cord-005646-xhx9pzhj 566 13 years year NNS cord-005646-xhx9pzhj 566 14 ( ( -LRB- cord-005646-xhx9pzhj 566 15 moan moan VB cord-005646-xhx9pzhj 566 16 = = SYM cord-005646-xhx9pzhj 566 17 2,5years 2,5years CD cord-005646-xhx9pzhj 566 18 ) ) -RRB- cord-005646-xhx9pzhj 566 19 . . . cord-005646-xhx9pzhj 567 1 Kerosene kerosene NN cord-005646-xhx9pzhj 567 2 is be VBZ cord-005646-xhx9pzhj 567 3 found find VBN cord-005646-xhx9pzhj 567 4 in in IN cord-005646-xhx9pzhj 567 5 35,8 35,8 CD cord-005646-xhx9pzhj 567 6 % % NN cord-005646-xhx9pzhj 567 7 of of IN cord-005646-xhx9pzhj 567 8 cases case NNS cord-005646-xhx9pzhj 567 9 ; ; , cord-005646-xhx9pzhj 567 10 all all DT cord-005646-xhx9pzhj 567 11 were be VBD cord-005646-xhx9pzhj 567 12 admitted admit VBN cord-005646-xhx9pzhj 567 13 ( ( -LRB- cord-005646-xhx9pzhj 567 14 mean mean NN cord-005646-xhx9pzhj 567 15 = = SYM cord-005646-xhx9pzhj 567 16 2,8 2,8 CD cord-005646-xhx9pzhj 567 17 days day NNS cord-005646-xhx9pzhj 567 18 ) ) -RRB- cord-005646-xhx9pzhj 567 19 . . . cord-005646-xhx9pzhj 568 1 79,1 79,1 CD cord-005646-xhx9pzhj 568 2 % % NN cord-005646-xhx9pzhj 568 3 were be VBD cord-005646-xhx9pzhj 568 4 symptomatic symptomatic JJ cord-005646-xhx9pzhj 568 5 on on IN cord-005646-xhx9pzhj 568 6 first first JJ cord-005646-xhx9pzhj 568 7 examination examination NN cord-005646-xhx9pzhj 568 8 but but CC cord-005646-xhx9pzhj 568 9 93 93 CD cord-005646-xhx9pzhj 568 10 % % NN cord-005646-xhx9pzhj 568 11 of of IN cord-005646-xhx9pzhj 568 12 all all DT cord-005646-xhx9pzhj 568 13 children child NNS cord-005646-xhx9pzhj 568 14 presented present VBD cord-005646-xhx9pzhj 568 15 signs sign NNS cord-005646-xhx9pzhj 568 16 of of IN cord-005646-xhx9pzhj 568 17 gastric gastric JJ cord-005646-xhx9pzhj 568 18 ( ( -LRB- cord-005646-xhx9pzhj 568 19 58 58 CD cord-005646-xhx9pzhj 568 20 % % NN cord-005646-xhx9pzhj 568 21 ) ) -RRB- cord-005646-xhx9pzhj 568 22 or or CC cord-005646-xhx9pzhj 568 23 respiratory respiratory JJ cord-005646-xhx9pzhj 568 24 ( ( -LRB- cord-005646-xhx9pzhj 568 25 69,8 69,8 CD cord-005646-xhx9pzhj 568 26 % % NN cord-005646-xhx9pzhj 568 27 ) ) -RRB- cord-005646-xhx9pzhj 568 28 irritation irritation NN cord-005646-xhx9pzhj 568 29 sometime sometime RB cord-005646-xhx9pzhj 568 30 during during IN cord-005646-xhx9pzhj 568 31 their -PRON- PRP$ cord-005646-xhx9pzhj 568 32 history history NN cord-005646-xhx9pzhj 568 33 ; ; : cord-005646-xhx9pzhj 568 34 37,2 37,2 CD cord-005646-xhx9pzhj 568 35 % % NN cord-005646-xhx9pzhj 568 36 had have VBD cord-005646-xhx9pzhj 568 37 neurological neurological JJ cord-005646-xhx9pzhj 568 38 signs sign NNS cord-005646-xhx9pzhj 568 39 and and CC cord-005646-xhx9pzhj 568 40 41,9 41,9 CD cord-005646-xhx9pzhj 568 41 % % NN cord-005646-xhx9pzhj 568 42 presented present VBD cord-005646-xhx9pzhj 568 43 some some DT cord-005646-xhx9pzhj 568 44 fever fever NN cord-005646-xhx9pzhj 568 45 . . . cord-005646-xhx9pzhj 569 1 Leucocytosis Leucocytosis NNP cord-005646-xhx9pzhj 569 2 is be VBZ cord-005646-xhx9pzhj 569 3 found find VBN cord-005646-xhx9pzhj 569 4 in in IN cord-005646-xhx9pzhj 569 5 65 65 CD cord-005646-xhx9pzhj 569 6 % % NN cord-005646-xhx9pzhj 569 7 of of IN cord-005646-xhx9pzhj 569 8 cases case NNS cord-005646-xhx9pzhj 569 9 ; ; : cord-005646-xhx9pzhj 569 10 25,6 25,6 CD cord-005646-xhx9pzhj 569 11 % % NN cord-005646-xhx9pzhj 569 12 of of IN cord-005646-xhx9pzhj 569 13 the the DT cord-005646-xhx9pzhj 569 14 children child NNS cord-005646-xhx9pzhj 569 15 received receive VBD cord-005646-xhx9pzhj 569 16 antibiotics antibiotic NNS cord-005646-xhx9pzhj 569 17 . . . cord-005646-xhx9pzhj 570 1 Chest Chest NNP cord-005646-xhx9pzhj 570 2 X X NNP cord-005646-xhx9pzhj 570 3 Ray Ray NNP cord-005646-xhx9pzhj 570 4 was be VBD cord-005646-xhx9pzhj 570 5 abnormal abnormal JJ cord-005646-xhx9pzhj 570 6 in in IN cord-005646-xhx9pzhj 570 7 48,8 48,8 CD cord-005646-xhx9pzhj 570 8 % % NN cord-005646-xhx9pzhj 570 9 of of IN cord-005646-xhx9pzhj 570 10 cases case NNS cord-005646-xhx9pzhj 570 11 : : : cord-005646-xhx9pzhj 570 12 mainly mainly RB cord-005646-xhx9pzhj 570 13 parahilar parahilar NNP cord-005646-xhx9pzhj 570 14 infiltrates infiltrate VBZ cord-005646-xhx9pzhj 570 15 were be VBD cord-005646-xhx9pzhj 570 16 found find VBN cord-005646-xhx9pzhj 570 17 , , , cord-005646-xhx9pzhj 570 18 All all DT cord-005646-xhx9pzhj 570 19 children child NNS cord-005646-xhx9pzhj 570 20 survived survive VBD cord-005646-xhx9pzhj 570 21 ; ; : cord-005646-xhx9pzhj 570 22 76,7 76,7 CD cord-005646-xhx9pzhj 570 23 % % NN cord-005646-xhx9pzhj 570 24 with with IN cord-005646-xhx9pzhj 570 25 a a DT cord-005646-xhx9pzhj 570 26 normal normal JJ cord-005646-xhx9pzhj 570 27 course course NN cord-005646-xhx9pzhj 570 28 ( ( -LRB- cord-005646-xhx9pzhj 570 29 1,9 1,9 CD cord-005646-xhx9pzhj 570 30 days day NNS cord-005646-xhx9pzhj 570 31 of of IN cord-005646-xhx9pzhj 570 32 hospital hospital NN cord-005646-xhx9pzhj 570 33 stay stay NN cord-005646-xhx9pzhj 570 34 ) ) -RRB- cord-005646-xhx9pzhj 570 35 whereas whereas IN cord-005646-xhx9pzhj 570 36 those those DT cord-005646-xhx9pzhj 570 37 who who WP cord-005646-xhx9pzhj 570 38 presented present VBD cord-005646-xhx9pzhj 570 39 complications complication NNS cord-005646-xhx9pzhj 570 40 ( ( -LRB- cord-005646-xhx9pzhj 570 41 severe severe JJ cord-005646-xhx9pzhj 570 42 pneumonia pneumonia NN cord-005646-xhx9pzhj 570 43 , , , cord-005646-xhx9pzhj 570 44 coma coma NN cord-005646-xhx9pzhj 570 45 ) ) -RRB- cord-005646-xhx9pzhj 570 46 stayed stay VBD cord-005646-xhx9pzhj 570 47 in in IN cord-005646-xhx9pzhj 570 48 the the DT cord-005646-xhx9pzhj 570 49 hospital hospital NN cord-005646-xhx9pzhj 570 50 for for IN cord-005646-xhx9pzhj 570 51 6 6 CD cord-005646-xhx9pzhj 570 52 days day NNS cord-005646-xhx9pzhj 570 53 ( ( -LRB- cord-005646-xhx9pzhj 570 54 mean mean VB cord-005646-xhx9pzhj 570 55 ) ) -RRB- cord-005646-xhx9pzhj 570 56 with with IN cord-005646-xhx9pzhj 570 57 short short JJ cord-005646-xhx9pzhj 570 58 course course NN cord-005646-xhx9pzhj 570 59 of of IN cord-005646-xhx9pzhj 570 60 assisted assist VBN cord-005646-xhx9pzhj 570 61 ventilation ventilation NN cord-005646-xhx9pzhj 570 62 for for IN cord-005646-xhx9pzhj 570 63 two two CD cord-005646-xhx9pzhj 570 64 of of IN cord-005646-xhx9pzhj 570 65 them -PRON- PRP cord-005646-xhx9pzhj 570 66 ; ; : cord-005646-xhx9pzhj 570 67 long long JJ cord-005646-xhx9pzhj 570 68 term term NN cord-005646-xhx9pzhj 570 69 follow follow VB cord-005646-xhx9pzhj 570 70 up up RP cord-005646-xhx9pzhj 571 1 was be VBD cord-005646-xhx9pzhj 571 2 not not RB cord-005646-xhx9pzhj 571 3 possible possible JJ cord-005646-xhx9pzhj 571 4 . . . cord-005646-xhx9pzhj 572 1 We -PRON- PRP cord-005646-xhx9pzhj 572 2 fonnd fonnd VBP cord-005646-xhx9pzhj 572 3 Nick Nick NNP cord-005646-xhx9pzhj 572 4 's 's POS cord-005646-xhx9pzhj 572 5 criteria criterion NNS cord-005646-xhx9pzhj 572 6 for for IN cord-005646-xhx9pzhj 572 7 hospital hospital NN cord-005646-xhx9pzhj 572 8 admission admission NN cord-005646-xhx9pzhj 572 9 to to TO cord-005646-xhx9pzhj 572 10 be be VB cord-005646-xhx9pzhj 572 11 of of IN cord-005646-xhx9pzhj 572 12 value value NN cord-005646-xhx9pzhj 572 13 : : : cord-005646-xhx9pzhj 573 1 -symptomatic -symptomatic JJ cord-005646-xhx9pzhj 573 2 children child NNS cord-005646-xhx9pzhj 573 3 with with IN cord-005646-xhx9pzhj 573 4 normal normal JJ cord-005646-xhx9pzhj 573 5 X x NN cord-005646-xhx9pzhj 573 6 Ray Ray NNP cord-005646-xhx9pzhj 573 7 } } -RRB- cord-005646-xhx9pzhj 573 8 6 6 CD cord-005646-xhx9pzhj 573 9 to to TO cord-005646-xhx9pzhj 573 10 8 8 CD cord-005646-xhx9pzhj 573 11 hours hour NNS cord-005646-xhx9pzhj 573 12 monitoring monitor VBG cord-005646-xhx9pzhj 573 13 -asymptomatie -asymptomatie JJ cord-005646-xhx9pzhj 573 14 children child NNS cord-005646-xhx9pzhj 573 15 with with IN cord-005646-xhx9pzhj 573 16 X X NNP cord-005646-xhx9pzhj 573 17 Ray Ray NNP cord-005646-xhx9pzhj 573 18 abnormality abnormality NN cord-005646-xhx9pzhj 573 19 } } -RRB- cord-005646-xhx9pzhj 573 20 -symptomatic -symptomatic JJ cord-005646-xhx9pzhj 573 21 children child NNS cord-005646-xhx9pzhj 573 22 with with IN cord-005646-xhx9pzhj 573 23 X X NNP cord-005646-xhx9pzhj 573 24 Ray Ray NNP cord-005646-xhx9pzhj 573 25 abnormality abnormality NN cord-005646-xhx9pzhj 573 26 : : : cord-005646-xhx9pzhj 573 27 Hospital hospital NN cord-005646-xhx9pzhj 573 28 admission admission NN cord-005646-xhx9pzhj 574 1 -asymptomatic -asymptomatic JJ cord-005646-xhx9pzhj 575 1 children child NNS cord-005646-xhx9pzhj 575 2 with with IN cord-005646-xhx9pzhj 575 3 normal normal JJ cord-005646-xhx9pzhj 575 4 X x NN cord-005646-xhx9pzhj 575 5 Ray ray NN cord-005646-xhx9pzhj 575 6 : : : cord-005646-xhx9pzhj 575 7 no no DT cord-005646-xhx9pzhj 575 8 admission admission NN cord-005646-xhx9pzhj 575 9 . . . cord-005646-xhx9pzhj 576 1 These these DT cord-005646-xhx9pzhj 576 2 criteria criterion NNS cord-005646-xhx9pzhj 576 3 would would MD cord-005646-xhx9pzhj 576 4 have have VB cord-005646-xhx9pzhj 576 5 helped help VBN cord-005646-xhx9pzhj 576 6 to to TO cord-005646-xhx9pzhj 576 7 avoid avoid VB cord-005646-xhx9pzhj 576 8 admission admission NN cord-005646-xhx9pzhj 576 9 in in IN cord-005646-xhx9pzhj 576 10 8 8 CD cord-005646-xhx9pzhj 576 11 children child NNS cord-005646-xhx9pzhj 576 12 and and CC cord-005646-xhx9pzhj 576 13 would would MD cord-005646-xhx9pzhj 576 14 have have VB cord-005646-xhx9pzhj 576 15 allowed allow VBN cord-005646-xhx9pzhj 576 16 a a DT cord-005646-xhx9pzhj 576 17 short short JJ cord-005646-xhx9pzhj 576 18 t2 t2 NNP cord-005646-xhx9pzhj 576 19 hours hour NNS cord-005646-xhx9pzhj 576 20 stay stay VBP cord-005646-xhx9pzhj 576 21 for for IN cord-005646-xhx9pzhj 576 22 6 6 CD cord-005646-xhx9pzhj 576 23 more more JJR cord-005646-xhx9pzhj 576 24 . . . cord-005646-xhx9pzhj 577 1 We -PRON- PRP cord-005646-xhx9pzhj 577 2 found find VBD cord-005646-xhx9pzhj 577 3 chest chest NN cord-005646-xhx9pzhj 577 4 X X NNP cord-005646-xhx9pzhj 577 5 Ray Ray NNP cord-005646-xhx9pzhj 577 6 to to TO cord-005646-xhx9pzhj 577 7 be be VB cord-005646-xhx9pzhj 577 8 mandatory mandatory JJ cord-005646-xhx9pzhj 577 9 in in IN cord-005646-xhx9pzhj 577 10 carbohydrate carbohydrate NN cord-005646-xhx9pzhj 577 11 ingestion ingestion NN cord-005646-xhx9pzhj 577 12 ; ; : cord-005646-xhx9pzhj 577 13 other other JJ cord-005646-xhx9pzhj 577 14 tests test NNS cord-005646-xhx9pzhj 577 15 were be VBD cord-005646-xhx9pzhj 577 16 not not RB cord-005646-xhx9pzhj 577 17 helpful helpful JJ cord-005646-xhx9pzhj 577 18 , , , cord-005646-xhx9pzhj 577 19 aside aside RB cord-005646-xhx9pzhj 577 20 arterial arterial JJ cord-005646-xhx9pzhj 577 21 blood blood NN cord-005646-xhx9pzhj 577 22 gases gas NNS cord-005646-xhx9pzhj 577 23 measurement measurement NN cord-005646-xhx9pzhj 577 24 in in IN cord-005646-xhx9pzhj 577 25 case case NN cord-005646-xhx9pzhj 577 26 of of IN cord-005646-xhx9pzhj 577 27 respiratory respiratory JJ cord-005646-xhx9pzhj 577 28 involvement involvement NN cord-005646-xhx9pzhj 577 29 ; ; : cord-005646-xhx9pzhj 577 30 we -PRON- PRP cord-005646-xhx9pzhj 577 31 now now RB cord-005646-xhx9pzhj 577 32 also also RB cord-005646-xhx9pzhj 577 33 advocate advocate VBP cord-005646-xhx9pzhj 577 34 more more JJR cord-005646-xhx9pzhj 577 35 restriction restriction NN cord-005646-xhx9pzhj 577 36 in in IN cord-005646-xhx9pzhj 577 37 antibiotic antibiotic JJ cord-005646-xhx9pzhj 577 38 use use NN cord-005646-xhx9pzhj 577 39 . . . cord-005646-xhx9pzhj 578 1 Prevention prevention NN cord-005646-xhx9pzhj 578 2 remains remain VBZ cord-005646-xhx9pzhj 578 3 efficient efficient JJ cord-005646-xhx9pzhj 578 4 and and CC cord-005646-xhx9pzhj 578 5 should should MD cord-005646-xhx9pzhj 578 6 be be VB cord-005646-xhx9pzhj 578 7 stressed stress VBN cord-005646-xhx9pzhj 578 8 on on IN cord-005646-xhx9pzhj 578 9 . . . cord-005646-xhx9pzhj 579 1 Severe severe JJ cord-005646-xhx9pzhj 579 2 liver liver NN cord-005646-xhx9pzhj 579 3 failure failure NN cord-005646-xhx9pzhj 579 4 [ [ -LRB- cord-005646-xhx9pzhj 579 5 SLF SLF NNP cord-005646-xhx9pzhj 579 6 ] ] -RRB- cord-005646-xhx9pzhj 579 7 is be VBZ cord-005646-xhx9pzhj 579 8 a a DT cord-005646-xhx9pzhj 579 9 rare rare JJ cord-005646-xhx9pzhj 579 10 but but CC cord-005646-xhx9pzhj 579 11 severe severe JJ cord-005646-xhx9pzhj 579 12 condition condition NN cord-005646-xhx9pzhj 579 13 in in IN cord-005646-xhx9pzhj 579 14 infants infant NNS cord-005646-xhx9pzhj 579 15 . . . cord-005646-xhx9pzhj 580 1 We -PRON- PRP cord-005646-xhx9pzhj 580 2 report report VBP cord-005646-xhx9pzhj 580 3 our -PRON- PRP$ cord-005646-xhx9pzhj 580 4 experience experience NN cord-005646-xhx9pzhj 580 5 . . . cord-005646-xhx9pzhj 581 1 Patients patient NNS cord-005646-xhx9pzhj 581 2 : : : cord-005646-xhx9pzhj 581 3 SLF SLF NNP cord-005646-xhx9pzhj 581 4 was be VBD cord-005646-xhx9pzhj 581 5 defined define VBN cord-005646-xhx9pzhj 581 6 as as IN cord-005646-xhx9pzhj 581 7 liver liver NN cord-005646-xhx9pzhj 581 8 insufficiency insufficiency NN cord-005646-xhx9pzhj 581 9 with with IN cord-005646-xhx9pzhj 581 10 hepatic hepatic JJ cord-005646-xhx9pzhj 581 11 encephalopathy encephalopathy NN cord-005646-xhx9pzhj 581 12 and and CC cord-005646-xhx9pzhj 581 13 a a DT cord-005646-xhx9pzhj 581 14 decrease decrease NN cord-005646-xhx9pzhj 581 15 in in IN cord-005646-xhx9pzhj 581 16 the the DT cord-005646-xhx9pzhj 581 17 level level NN cord-005646-xhx9pzhj 581 18 of of IN cord-005646-xhx9pzhj 581 19 factor factor NN cord-005646-xhx9pzhj 581 20 V v NN cord-005646-xhx9pzhj 581 21 to to IN cord-005646-xhx9pzhj 581 22 below below IN cord-005646-xhx9pzhj 581 23 25 25 CD cord-005646-xhx9pzhj 581 24 % % NN cord-005646-xhx9pzhj 581 25 . . . cord-005646-xhx9pzhj 582 1 Between between IN cord-005646-xhx9pzhj 582 2 1984 1984 CD cord-005646-xhx9pzhj 582 3 and and CC cord-005646-xhx9pzhj 582 4 1996 1996 CD cord-005646-xhx9pzhj 582 5 , , , cord-005646-xhx9pzhj 582 6 29 29 CD cord-005646-xhx9pzhj 582 7 infants infant NNS cord-005646-xhx9pzhj 582 8 ( ( -LRB- cord-005646-xhx9pzhj 582 9 mean mean VB cord-005646-xhx9pzhj 582 10 : : : cord-005646-xhx9pzhj 582 11 4 4 CD cord-005646-xhx9pzhj 582 12 mo mo NNP cord-005646-xhx9pzhj 582 13 ) ) -RRB- cord-005646-xhx9pzhj 582 14 were be VBD cord-005646-xhx9pzhj 582 15 admitted admit VBN cord-005646-xhx9pzhj 582 16 for for IN cord-005646-xhx9pzhj 582 17 SLF SLF NNP cord-005646-xhx9pzhj 582 18 ( ( -LRB- cord-005646-xhx9pzhj 582 19 neonates neonate NNS cord-005646-xhx9pzhj 582 20 excluded exclude VBN cord-005646-xhx9pzhj 582 21 ) ) -RRB- cord-005646-xhx9pzhj 582 22 . . . cord-005646-xhx9pzhj 583 1 Main main JJ cord-005646-xhx9pzhj 583 2 causes cause NNS cord-005646-xhx9pzhj 583 3 were be VBD cord-005646-xhx9pzhj 583 4 metabolic metabolic JJ cord-005646-xhx9pzhj 583 5 disorders disorder NNS cord-005646-xhx9pzhj 583 6 ( ( -LRB- cord-005646-xhx9pzhj 583 7 41.3 41.3 CD cord-005646-xhx9pzhj 583 8 % % NN cord-005646-xhx9pzhj 583 9 ) ) -RRB- cord-005646-xhx9pzhj 583 10 ( ( -LRB- cord-005646-xhx9pzhj 583 11 tyrosinemian=5 tyrosinemian=5 FW cord-005646-xhx9pzhj 583 12 , , , cord-005646-xhx9pzhj 583 13 hemochromatosis hemochromatosis NN cord-005646-xhx9pzhj 583 14 n=2 n=2 NNS cord-005646-xhx9pzhj 583 15 , , , cord-005646-xhx9pzhj 583 16 Reye Reye NNP cord-005646-xhx9pzhj 583 17 's 's POS cord-005646-xhx9pzhj 583 18 syndrome syndrome NN cord-005646-xhx9pzhj 583 19 n=2 n=2 NNS cord-005646-xhx9pzhj 583 20 , , , cord-005646-xhx9pzhj 583 21 other other JJ cord-005646-xhx9pzhj 583 22 n=3 n=3 NN cord-005646-xhx9pzhj 583 23 ) ) -RRB- cord-005646-xhx9pzhj 583 24 , , , cord-005646-xhx9pzhj 583 25 virus virus NN cord-005646-xhx9pzhj 583 26 - - HYPH cord-005646-xhx9pzhj 583 27 induced induce VBN cord-005646-xhx9pzhj 583 28 FLF FLF NNP cord-005646-xhx9pzhj 583 29 ( ( -LRB- cord-005646-xhx9pzhj 583 30 20.6 20.6 CD cord-005646-xhx9pzhj 583 31 % % NN cord-005646-xhx9pzhj 583 32 ) ) -RRB- cord-005646-xhx9pzhj 583 33 and and CC cord-005646-xhx9pzhj 583 34 hematologic hematologic JJ cord-005646-xhx9pzhj 583 35 diseases disease NNS cord-005646-xhx9pzhj 583 36 ( ( -LRB- cord-005646-xhx9pzhj 583 37 13.7 13.7 CD cord-005646-xhx9pzhj 583 38 % % NN cord-005646-xhx9pzhj 583 39 ) ) -RRB- cord-005646-xhx9pzhj 583 40 . . . cord-005646-xhx9pzhj 584 1 In in IN cord-005646-xhx9pzhj 584 2 4 4 CD cord-005646-xhx9pzhj 584 3 cases case NNS cord-005646-xhx9pzhj 584 4 , , , cord-005646-xhx9pzhj 584 5 the the DT cord-005646-xhx9pzhj 584 6 causes cause NNS cord-005646-xhx9pzhj 584 7 remained remain VBD cord-005646-xhx9pzhj 584 8 undetermined undetermined JJ cord-005646-xhx9pzhj 584 9 . . . cord-005646-xhx9pzhj 585 1 Results result NNS cord-005646-xhx9pzhj 585 2 : : : cord-005646-xhx9pzhj 586 1 OLT OLT NNP cord-005646-xhx9pzhj 586 2 was be VBD cord-005646-xhx9pzhj 586 3 contraindicated contraindicate VBN cord-005646-xhx9pzhj 586 4 in in IN cord-005646-xhx9pzhj 586 5 12 12 CD cord-005646-xhx9pzhj 586 6 cases case NNS cord-005646-xhx9pzhj 586 7 because because IN cord-005646-xhx9pzhj 586 8 of of IN cord-005646-xhx9pzhj 586 9 multiple multiple JJ cord-005646-xhx9pzhj 586 10 organ organ NN cord-005646-xhx9pzhj 586 11 failure failure NN cord-005646-xhx9pzhj 586 12 ( ( -LRB- cord-005646-xhx9pzhj 586 13 n=10 n=10 NNP cord-005646-xhx9pzhj 586 14 ) ) -RRB- cord-005646-xhx9pzhj 586 15 , , , cord-005646-xhx9pzhj 586 16 or or CC cord-005646-xhx9pzhj 586 17 underlying underlying JJ cord-005646-xhx9pzhj 586 18 disease disease NN cord-005646-xhx9pzhj 586 19 . . . cord-005646-xhx9pzhj 587 1 All all DT cord-005646-xhx9pzhj 587 2 of of IN cord-005646-xhx9pzhj 587 3 them -PRON- PRP cord-005646-xhx9pzhj 587 4 died die VBD cord-005646-xhx9pzhj 587 5 within within IN cord-005646-xhx9pzhj 587 6 6 6 CD cord-005646-xhx9pzhj 587 7 days day NNS cord-005646-xhx9pzhj 587 8 after after IN cord-005646-xhx9pzhj 587 9 admission admission NN cord-005646-xhx9pzhj 587 10 . . . cord-005646-xhx9pzhj 588 1 7 7 CD cord-005646-xhx9pzhj 588 2 patients patient NNS cord-005646-xhx9pzhj 588 3 had have VBD cord-005646-xhx9pzhj 588 4 no no DT cord-005646-xhx9pzhj 588 5 indications indication NNS cord-005646-xhx9pzhj 588 6 for for IN cord-005646-xhx9pzhj 588 7 OLT OLT NNP cord-005646-xhx9pzhj 588 8 , , , cord-005646-xhx9pzhj 588 9 all all DT cord-005646-xhx9pzhj 588 10 but but IN cord-005646-xhx9pzhj 588 11 one one CD cord-005646-xhx9pzhj 588 12 are be VBP cord-005646-xhx9pzhj 588 13 alive alive JJ cord-005646-xhx9pzhj 588 14 . . . cord-005646-xhx9pzhj 589 1 ( ( -LRB- cord-005646-xhx9pzhj 589 2 1 1 CD cord-005646-xhx9pzhj 589 3 of of IN cord-005646-xhx9pzhj 589 4 them -PRON- PRP cord-005646-xhx9pzhj 589 5 was be VBD cord-005646-xhx9pzhj 589 6 transplanted transplant VBN cord-005646-xhx9pzhj 589 7 later later RB cord-005646-xhx9pzhj 589 8 for for IN cord-005646-xhx9pzhj 589 9 tyrosinemia tyrosinemia NNP cord-005646-xhx9pzhj 589 10 and and CC cord-005646-xhx9pzhj 589 11 1 1 CD cord-005646-xhx9pzhj 589 12 died die VBD cord-005646-xhx9pzhj 589 13 lately lately RB cord-005646-xhx9pzhj 589 14 ( ( -LRB- cord-005646-xhx9pzhj 589 15 virus virus NN cord-005646-xhx9pzhj 589 16 induced induce VBN cord-005646-xhx9pzhj 589 17 - - HYPH cord-005646-xhx9pzhj 589 18 SLF SLF NNP cord-005646-xhx9pzhj 589 19 ) ) -RRB- cord-005646-xhx9pzhj 589 20 . . . cord-005646-xhx9pzhj 590 1 Among among IN cord-005646-xhx9pzhj 590 2 the the DT cord-005646-xhx9pzhj 590 3 t0 t0 NNP cord-005646-xhx9pzhj 590 4 infants infant NNS cord-005646-xhx9pzhj 590 5 who who WP cord-005646-xhx9pzhj 590 6 underwent undergo VBD cord-005646-xhx9pzhj 590 7 emergency emergency NN cord-005646-xhx9pzhj 590 8 OLT OLT NNP cord-005646-xhx9pzhj 590 9 , , , cord-005646-xhx9pzhj 590 10 6 6 CD cord-005646-xhx9pzhj 590 11 are be VBP cord-005646-xhx9pzhj 590 12 alive alive JJ cord-005646-xhx9pzhj 590 13 and and CC cord-005646-xhx9pzhj 590 14 4 4 CD cord-005646-xhx9pzhj 590 15 died die VBD cord-005646-xhx9pzhj 590 16 because because IN cord-005646-xhx9pzhj 590 17 of of IN cord-005646-xhx9pzhj 590 18 primary primary JJ cord-005646-xhx9pzhj 590 19 non non JJ cord-005646-xhx9pzhj 590 20 function function NN cord-005646-xhx9pzhj 590 21 of of IN cord-005646-xhx9pzhj 590 22 the the DT cord-005646-xhx9pzhj 590 23 graft graft NN cord-005646-xhx9pzhj 590 24 . . . cord-005646-xhx9pzhj 591 1 Conclusion conclusion NN cord-005646-xhx9pzhj 591 2 : : : cord-005646-xhx9pzhj 591 3 SLF SLF NNP cord-005646-xhx9pzhj 591 4 in in IN cord-005646-xhx9pzhj 591 5 infants infant NNS cord-005646-xhx9pzhj 591 6 admitted admit VBN cord-005646-xhx9pzhj 591 7 before before IN cord-005646-xhx9pzhj 591 8 their -PRON- PRP$ cord-005646-xhx9pzhj 591 9 first first JJ cord-005646-xhx9pzhj 591 10 birthday birthday NN cord-005646-xhx9pzhj 591 11 is be VBZ cord-005646-xhx9pzhj 591 12 a a DT cord-005646-xhx9pzhj 591 13 severe severe JJ cord-005646-xhx9pzhj 591 14 condition condition NN cord-005646-xhx9pzhj 591 15 with with IN cord-005646-xhx9pzhj 591 16 an an DT cord-005646-xhx9pzhj 591 17 overall overall JJ cord-005646-xhx9pzhj 591 18 mortality mortality NN cord-005646-xhx9pzhj 591 19 rate rate NN cord-005646-xhx9pzhj 591 20 reaching reach VBG cord-005646-xhx9pzhj 591 21 60 60 CD cord-005646-xhx9pzhj 591 22 % % NN cord-005646-xhx9pzhj 591 23 . . . cord-005646-xhx9pzhj 592 1 Inherited inherit VBN cord-005646-xhx9pzhj 592 2 metabolic metabolic JJ cord-005646-xhx9pzhj 592 3 disorders disorder NNS cord-005646-xhx9pzhj 592 4 are be VBP cord-005646-xhx9pzhj 592 5 the the DT cord-005646-xhx9pzhj 592 6 first first JJ cord-005646-xhx9pzhj 592 7 cause cause NN cord-005646-xhx9pzhj 592 8 of of IN cord-005646-xhx9pzhj 592 9 SLF SLF NNP cord-005646-xhx9pzhj 592 10 at at IN cord-005646-xhx9pzhj 592 11 this this DT cord-005646-xhx9pzhj 592 12 age age NN cord-005646-xhx9pzhj 592 13 . . . cord-005646-xhx9pzhj 593 1 Contraindications Contraindications NNP cord-005646-xhx9pzhj 593 2 for for IN cord-005646-xhx9pzhj 593 3 OLT OLT NNP cord-005646-xhx9pzhj 593 4 are be VBP cord-005646-xhx9pzhj 593 5 frequent frequent JJ cord-005646-xhx9pzhj 593 6 because because IN cord-005646-xhx9pzhj 593 7 of of IN cord-005646-xhx9pzhj 593 8 underlying underlie VBG cord-005646-xhx9pzhj 593 9 disease disease NN cord-005646-xhx9pzhj 593 10 or or CC cord-005646-xhx9pzhj 593 11 multiple multiple JJ cord-005646-xhx9pzhj 593 12 organ organ NN cord-005646-xhx9pzhj 593 13 failure failure NN cord-005646-xhx9pzhj 593 14 . . . cord-005646-xhx9pzhj 594 1 A a DT cord-005646-xhx9pzhj 594 2 number number NN cord-005646-xhx9pzhj 594 3 of of IN cord-005646-xhx9pzhj 594 4 children child NNS cord-005646-xhx9pzhj 594 5 undergo undergo VB cord-005646-xhx9pzhj 594 6 primary primary JJ cord-005646-xhx9pzhj 594 7 graft graft NN cord-005646-xhx9pzhj 594 8 failure failure NN cord-005646-xhx9pzhj 594 9 after after IN cord-005646-xhx9pzhj 594 10 liver liver NN cord-005646-xhx9pzhj 594 11 transplantation transplantation NN cord-005646-xhx9pzhj 594 12 . . . cord-005646-xhx9pzhj 595 1 It -PRON- PRP cord-005646-xhx9pzhj 595 2 is be VBZ cord-005646-xhx9pzhj 595 3 unknown unknown JJ cord-005646-xhx9pzhj 595 4 if if IN cord-005646-xhx9pzhj 595 5 there there EX cord-005646-xhx9pzhj 595 6 is be VBZ cord-005646-xhx9pzhj 595 7 any any DT cord-005646-xhx9pzhj 595 8 increased increased JJ cord-005646-xhx9pzhj 595 9 morbidity morbidity NN cord-005646-xhx9pzhj 595 10 or or CC cord-005646-xhx9pzhj 595 11 mortality mortality NN cord-005646-xhx9pzhj 595 12 following follow VBG cord-005646-xhx9pzhj 595 13 retransplantation retransplantation NN cord-005646-xhx9pzhj 595 14 . . . cord-005646-xhx9pzhj 596 1 This this DT cord-005646-xhx9pzhj 596 2 study study NN cord-005646-xhx9pzhj 596 3 seeks seek VBZ cord-005646-xhx9pzhj 596 4 to to TO cord-005646-xhx9pzhj 596 5 explore explore VB cord-005646-xhx9pzhj 596 6 these these DT cord-005646-xhx9pzhj 596 7 issues issue NNS cord-005646-xhx9pzhj 596 8 . . . cord-005646-xhx9pzhj 597 1 Methods method NNS cord-005646-xhx9pzhj 597 2 : : : cord-005646-xhx9pzhj 598 1 A a DT cord-005646-xhx9pzhj 598 2 pediatric pediatric JJ cord-005646-xhx9pzhj 598 3 intensive intensive JJ cord-005646-xhx9pzhj 598 4 care care NN cord-005646-xhx9pzhj 598 5 / / SYM cord-005646-xhx9pzhj 598 6 Iiver Iiver NNP cord-005646-xhx9pzhj 598 7 transplant transplant NN cord-005646-xhx9pzhj 598 8 database database NN cord-005646-xhx9pzhj 598 9 is be VBZ cord-005646-xhx9pzhj 598 10 in in IN cord-005646-xhx9pzhj 598 11 formation formation NN cord-005646-xhx9pzhj 598 12 . . . cord-005646-xhx9pzhj 599 1 Records record NNS cord-005646-xhx9pzhj 599 2 of of IN cord-005646-xhx9pzhj 599 3 all all DT cord-005646-xhx9pzhj 599 4 liver liver NN cord-005646-xhx9pzhj 599 5 transplant transplant NN cord-005646-xhx9pzhj 599 6 patients patient NNS cord-005646-xhx9pzhj 599 7 are be VBP cord-005646-xhx9pzhj 599 8 reviewed review VBN cord-005646-xhx9pzhj 599 9 and and CC cord-005646-xhx9pzhj 599 10 abstracted abstract VBN cord-005646-xhx9pzhj 599 11 . . . cord-005646-xhx9pzhj 600 1 This this DT cord-005646-xhx9pzhj 600 2 data data NN cord-005646-xhx9pzhj 600 3 is be VBZ cord-005646-xhx9pzhj 600 4 then then RB cord-005646-xhx9pzhj 600 5 computerized computerized JJ cord-005646-xhx9pzhj 600 6 to to TO cord-005646-xhx9pzhj 600 7 allow allow VB cord-005646-xhx9pzhj 600 8 analysis analysis NN cord-005646-xhx9pzhj 600 9 . . . cord-005646-xhx9pzhj 601 1 This this DT cord-005646-xhx9pzhj 601 2 data data NN cord-005646-xhx9pzhj 601 3 provides provide VBZ cord-005646-xhx9pzhj 601 4 the the DT cord-005646-xhx9pzhj 601 5 source source NN cord-005646-xhx9pzhj 601 6 for for IN cord-005646-xhx9pzhj 601 7 this this DT cord-005646-xhx9pzhj 601 8 study study NN cord-005646-xhx9pzhj 601 9 . . . cord-005646-xhx9pzhj 602 1 Statistical statistical JJ cord-005646-xhx9pzhj 602 2 analysis analysis NN cord-005646-xhx9pzhj 602 3 was be VBD cord-005646-xhx9pzhj 602 4 performed perform VBN cord-005646-xhx9pzhj 602 5 via via IN cord-005646-xhx9pzhj 602 6 Student Student NNP cord-005646-xhx9pzhj 602 7 's 's POS cord-005646-xhx9pzhj 602 8 t t NN cord-005646-xhx9pzhj 602 9 - - HYPH cord-005646-xhx9pzhj 602 10 test test NN cord-005646-xhx9pzhj 602 11 where where WRB cord-005646-xhx9pzhj 602 12 appropriate appropriate JJ cord-005646-xhx9pzhj 602 13 . . . cord-005646-xhx9pzhj 603 1 Results result NNS cord-005646-xhx9pzhj 603 2 : : : cord-005646-xhx9pzhj 604 1 Of of IN cord-005646-xhx9pzhj 604 2 the the DT cord-005646-xhx9pzhj 604 3 350 350 CD cord-005646-xhx9pzhj 604 4 patients patient NNS cord-005646-xhx9pzhj 604 5 who who WP cord-005646-xhx9pzhj 604 6 have have VBP cord-005646-xhx9pzhj 604 7 thus thus RB cord-005646-xhx9pzhj 604 8 far far RB cord-005646-xhx9pzhj 604 9 received receive VBN cord-005646-xhx9pzhj 604 10 at at IN cord-005646-xhx9pzhj 604 11 our -PRON- PRP$ cord-005646-xhx9pzhj 604 12 center center NN cord-005646-xhx9pzhj 604 13 orthotopic orthotopic JJ cord-005646-xhx9pzhj 604 14 liver liver NN cord-005646-xhx9pzhj 604 15 ransplants ransplant NNS cord-005646-xhx9pzhj 604 16 , , , cord-005646-xhx9pzhj 604 17 the the DT cord-005646-xhx9pzhj 604 18 records record NNS cord-005646-xhx9pzhj 604 19 of of IN cord-005646-xhx9pzhj 604 20 112 112 CD cord-005646-xhx9pzhj 604 21 who who WP cord-005646-xhx9pzhj 604 22 underwent undergo VBD cord-005646-xhx9pzhj 604 23 140 140 CD cord-005646-xhx9pzhj 604 24 transplants transplant NNS cord-005646-xhx9pzhj 604 25 form form VBP cord-005646-xhx9pzhj 604 26 the the DT cord-005646-xhx9pzhj 604 27 basis basis NN cord-005646-xhx9pzhj 604 28 for for IN cord-005646-xhx9pzhj 604 29 this this DT cord-005646-xhx9pzhj 604 30 review review NN cord-005646-xhx9pzhj 604 31 . . . cord-005646-xhx9pzhj 605 1 Twenty twenty CD cord-005646-xhx9pzhj 605 2 - - HYPH cord-005646-xhx9pzhj 605 3 three three CD cord-005646-xhx9pzhj 605 4 patients patient NNS cord-005646-xhx9pzhj 605 5 underwent undergo VBD cord-005646-xhx9pzhj 605 6 multiple multiple JJ cord-005646-xhx9pzhj 605 7 transplants transplant NNS cord-005646-xhx9pzhj 605 8 , , , cord-005646-xhx9pzhj 605 9 19 19 CD cord-005646-xhx9pzhj 605 10 required require VBD cord-005646-xhx9pzhj 605 11 one one CD cord-005646-xhx9pzhj 605 12 additional additional JJ cord-005646-xhx9pzhj 605 13 , , , cord-005646-xhx9pzhj 605 14 three three CD cord-005646-xhx9pzhj 605 15 required require VBN cord-005646-xhx9pzhj 605 16 3 3 CD cord-005646-xhx9pzhj 605 17 organs organ NNS cord-005646-xhx9pzhj 605 18 , , , cord-005646-xhx9pzhj 605 19 and and CC cord-005646-xhx9pzhj 606 1 one one CD cord-005646-xhx9pzhj 606 2 patient patient NN cord-005646-xhx9pzhj 606 3 survived survive VBD cord-005646-xhx9pzhj 606 4 after after IN cord-005646-xhx9pzhj 606 5 a a DT cord-005646-xhx9pzhj 606 6 fourth fourth JJ cord-005646-xhx9pzhj 606 7 organ organ NN cord-005646-xhx9pzhj 606 8 transplant transplant NN cord-005646-xhx9pzhj 606 9 , , , cord-005646-xhx9pzhj 606 10 There there EX cord-005646-xhx9pzhj 606 11 was be VBD cord-005646-xhx9pzhj 606 12 no no DT cord-005646-xhx9pzhj 606 13 significant significant JJ cord-005646-xhx9pzhj 606 14 difference difference NN cord-005646-xhx9pzhj 606 15 in in IN cord-005646-xhx9pzhj 606 16 age age NN cord-005646-xhx9pzhj 606 17 at at IN cord-005646-xhx9pzhj 606 18 first first JJ cord-005646-xhx9pzhj 606 19 transplant transplant NN cord-005646-xhx9pzhj 606 20 between between IN cord-005646-xhx9pzhj 606 21 those those DT cord-005646-xhx9pzhj 606 22 who who WP cord-005646-xhx9pzhj 606 23 received receive VBD cord-005646-xhx9pzhj 606 24 multiple multiple JJ cord-005646-xhx9pzhj 606 25 organs organ NNS cord-005646-xhx9pzhj 606 26 and and CC cord-005646-xhx9pzhj 606 27 those those DT cord-005646-xhx9pzhj 606 28 who who WP cord-005646-xhx9pzhj 606 29 did do VBD cord-005646-xhx9pzhj 606 30 not not RB cord-005646-xhx9pzhj 606 31 ( ( -LRB- cord-005646-xhx9pzhj 606 32 40 40 CD cord-005646-xhx9pzhj 606 33 vs vs IN cord-005646-xhx9pzhj 606 34 , , , cord-005646-xhx9pzhj 606 35 44 44 CD cord-005646-xhx9pzhj 606 36 months month NNS cord-005646-xhx9pzhj 606 37 , , , cord-005646-xhx9pzhj 606 38 p p NN cord-005646-xhx9pzhj 606 39 = = SYM cord-005646-xhx9pzhj 606 40 NS NS NNP cord-005646-xhx9pzhj 606 41 ) ) -RRB- cord-005646-xhx9pzhj 606 42 . . . cord-005646-xhx9pzhj 607 1 The the DT cord-005646-xhx9pzhj 607 2 anesthesia anesthesia NN cord-005646-xhx9pzhj 607 3 time time NN cord-005646-xhx9pzhj 607 4 for for IN cord-005646-xhx9pzhj 607 5 the the DT cord-005646-xhx9pzhj 607 6 procedure procedure NN cord-005646-xhx9pzhj 607 7 did do VBD cord-005646-xhx9pzhj 607 8 not not RB cord-005646-xhx9pzhj 607 9 significantly significantly RB cord-005646-xhx9pzhj 607 10 increase increase VB cord-005646-xhx9pzhj 607 11 tbr tbr NNP cord-005646-xhx9pzhj 607 12 subsequent subsequent JJ cord-005646-xhx9pzhj 607 13 transplants transplant NNS cord-005646-xhx9pzhj 607 14 ( ( -LRB- cord-005646-xhx9pzhj 607 15 8.3 8.3 CD cord-005646-xhx9pzhj 607 16 vs vs IN cord-005646-xhx9pzhj 607 17 , , , cord-005646-xhx9pzhj 607 18 7,3 7,3 CD cord-005646-xhx9pzhj 607 19 hours hour NNS cord-005646-xhx9pzhj 607 20 ) ) -RRB- cord-005646-xhx9pzhj 607 21 , , , cord-005646-xhx9pzhj 607 22 nor nor CC cord-005646-xhx9pzhj 607 23 did do VBD cord-005646-xhx9pzhj 607 24 time time NN cord-005646-xhx9pzhj 607 25 in in IN cord-005646-xhx9pzhj 607 26 the the DT cord-005646-xhx9pzhj 607 27 intensive intensive JJ cord-005646-xhx9pzhj 607 28 care care NN cord-005646-xhx9pzhj 607 29 unit unit NN cord-005646-xhx9pzhj 607 30 ( ( -LRB- cord-005646-xhx9pzhj 607 31 t6.6 t6.6 JJ cord-005646-xhx9pzhj 607 32 vs. vs. FW cord-005646-xhx9pzhj 607 33 22.2 22.2 CD cord-005646-xhx9pzhj 607 34 days day NNS cord-005646-xhx9pzhj 607 35 ) ) -RRB- cord-005646-xhx9pzhj 607 36 , , , cord-005646-xhx9pzhj 607 37 nor nor CC cord-005646-xhx9pzhj 607 38 did do VBD cord-005646-xhx9pzhj 607 39 time time NN cord-005646-xhx9pzhj 607 40 on on IN cord-005646-xhx9pzhj 607 41 the the DT cord-005646-xhx9pzhj 607 42 ventilator ventilator NN cord-005646-xhx9pzhj 607 43 ( ( -LRB- cord-005646-xhx9pzhj 607 44 8.4 8.4 CD cord-005646-xhx9pzhj 607 45 vs. vs. CC cord-005646-xhx9pzhj 607 46 15.3 15.3 CD cord-005646-xhx9pzhj 607 47 days day NNS cord-005646-xhx9pzhj 607 48 ) ) -RRB- cord-005646-xhx9pzhj 608 1 Subsequent subsequent JJ cord-005646-xhx9pzhj 608 2 transplants transplant NNS cord-005646-xhx9pzhj 608 3 did do VBD cord-005646-xhx9pzhj 608 4 not not RB cord-005646-xhx9pzhj 608 5 predispose predispose VB cord-005646-xhx9pzhj 608 6 to to IN cord-005646-xhx9pzhj 608 7 having have VBG cord-005646-xhx9pzhj 608 8 more more RBR cord-005646-xhx9pzhj 608 9 bleeding bleed VBG cord-005646-xhx9pzhj 608 10 in in IN cord-005646-xhx9pzhj 608 11 the the DT cord-005646-xhx9pzhj 608 12 intensive intensive JJ cord-005646-xhx9pzhj 608 13 care care NN cord-005646-xhx9pzhj 608 14 unit unit NN cord-005646-xhx9pzhj 608 15 for for IN cord-005646-xhx9pzhj 608 16 usage usage NN cord-005646-xhx9pzhj 608 17 of of IN cord-005646-xhx9pzhj 608 18 packed packed JJ cord-005646-xhx9pzhj 608 19 red red JJ cord-005646-xhx9pzhj 608 20 blood blood NN cord-005646-xhx9pzhj 608 21 cells cell NNS cord-005646-xhx9pzhj 608 22 or or CC cord-005646-xhx9pzhj 608 23 platalets platalet NNS cord-005646-xhx9pzhj 608 24 was be VBD cord-005646-xhx9pzhj 608 25 not not RB cord-005646-xhx9pzhj 608 26 significantly significantly RB cord-005646-xhx9pzhj 608 27 altered alter VBN cord-005646-xhx9pzhj 608 28 ( ( -LRB- cord-005646-xhx9pzhj 608 29 299 299 CD cord-005646-xhx9pzhj 608 30 vs vs IN cord-005646-xhx9pzhj 608 31 306 306 CD cord-005646-xhx9pzhj 608 32 ml ml NNS cord-005646-xhx9pzhj 608 33 and and CC cord-005646-xhx9pzhj 608 34 127 127 CD cord-005646-xhx9pzhj 608 35 vs vs IN cord-005646-xhx9pzhj 608 36 207 207 CD cord-005646-xhx9pzhj 608 37 ml ml NNS cord-005646-xhx9pzhj 608 38 respectively respectively RB cord-005646-xhx9pzhj 608 39 ) ) -RRB- cord-005646-xhx9pzhj 608 40 . . . cord-005646-xhx9pzhj 609 1 Patients patient NNS cord-005646-xhx9pzhj 609 2 who who WP cord-005646-xhx9pzhj 609 3 required require VBD cord-005646-xhx9pzhj 609 4 retransplantatior~ retransplantatior~ NNP cord-005646-xhx9pzhj 609 5 did do VBD cord-005646-xhx9pzhj 609 6 receive receive VB cord-005646-xhx9pzhj 609 7 mere mere JJ cord-005646-xhx9pzhj 609 8 fresh fresh JJ cord-005646-xhx9pzhj 609 9 frozen frozen JJ cord-005646-xhx9pzhj 609 10 plasma plasma NN cord-005646-xhx9pzhj 609 11 ( ( -LRB- cord-005646-xhx9pzhj 609 12 FFP)daring ffp)dare VBG cord-005646-xhx9pzhj 609 13 their -PRON- PRP$ cord-005646-xhx9pzhj 609 14 first first JJ cord-005646-xhx9pzhj 609 15 transplant transplant NN cord-005646-xhx9pzhj 609 16 than than IN cord-005646-xhx9pzhj 609 17 in in IN cord-005646-xhx9pzhj 609 18 the the DT cord-005646-xhx9pzhj 609 19 subsequent subsequent JJ cord-005646-xhx9pzhj 609 20 ones one NNS cord-005646-xhx9pzhj 609 21 ( ( -LRB- cord-005646-xhx9pzhj 609 22 275 275 CD cord-005646-xhx9pzhj 609 23 vs vs IN cord-005646-xhx9pzhj 609 24 81 81 CD cord-005646-xhx9pzhj 609 25 ec ec NNP cord-005646-xhx9pzhj 609 26 , , , cord-005646-xhx9pzhj 609 27 p p NN cord-005646-xhx9pzhj 609 28 < < XX cord-005646-xhx9pzhj 609 29 0.05 0.05 CD cord-005646-xhx9pzhj 609 30 ) ) -RRB- cord-005646-xhx9pzhj 609 31 . . . cord-005646-xhx9pzhj 610 1 However however RB cord-005646-xhx9pzhj 610 2 FFP FFP NNP cord-005646-xhx9pzhj 610 3 use use NN cord-005646-xhx9pzhj 610 4 was be VBD cord-005646-xhx9pzhj 610 5 not not RB cord-005646-xhx9pzhj 610 6 significantly significantly RB cord-005646-xhx9pzhj 610 7 different different JJ cord-005646-xhx9pzhj 610 8 than than IN cord-005646-xhx9pzhj 610 9 patients patient NNS cord-005646-xhx9pzhj 610 10 who who WP cord-005646-xhx9pzhj 610 11 did do VBD cord-005646-xhx9pzhj 610 12 not not RB cord-005646-xhx9pzhj 610 13 require require VB cord-005646-xhx9pzhj 610 14 retransplant retransplant JJ cord-005646-xhx9pzhj 610 15 . . . cord-005646-xhx9pzhj 611 1 Patients patient NNS cord-005646-xhx9pzhj 611 2 who who WP cord-005646-xhx9pzhj 611 3 underwent undergo VBD cord-005646-xhx9pzhj 611 4 retransplant retransplant NNP cord-005646-xhx9pzhj 611 5 had have VBD cord-005646-xhx9pzhj 611 6 a a DT cord-005646-xhx9pzhj 611 7 markedly markedly RB cord-005646-xhx9pzhj 611 8 increased increase VBN cord-005646-xhx9pzhj 611 9 mortality mortality NN cord-005646-xhx9pzhj 611 10 ( ( -LRB- cord-005646-xhx9pzhj 611 11 47 47 CD cord-005646-xhx9pzhj 611 12 % % NN cord-005646-xhx9pzhj 611 13 ) ) -RRB- cord-005646-xhx9pzhj 611 14 than than IN cord-005646-xhx9pzhj 611 15 the the DT cord-005646-xhx9pzhj 611 16 overall overall JJ cord-005646-xhx9pzhj 611 17 mortality mortality NN cord-005646-xhx9pzhj 611 18 for for IN cord-005646-xhx9pzhj 611 19 liver liver NN cord-005646-xhx9pzhj 611 20 transplants transplant NNS cord-005646-xhx9pzhj 611 21 at at IN cord-005646-xhx9pzhj 611 22 our -PRON- PRP$ cord-005646-xhx9pzhj 611 23 center center NN cord-005646-xhx9pzhj 611 24 ( ( -LRB- cord-005646-xhx9pzhj 611 25 20 20 CD cord-005646-xhx9pzhj 611 26 % % NN cord-005646-xhx9pzhj 611 27 ) ) -RRB- cord-005646-xhx9pzhj 612 1 , , , cord-005646-xhx9pzhj 612 2 Conclusion conclusion NN cord-005646-xhx9pzhj 612 3 : : : cord-005646-xhx9pzhj 613 1 Children child NNS cord-005646-xhx9pzhj 613 2 who who WP cord-005646-xhx9pzhj 613 3 require require VBP cord-005646-xhx9pzhj 613 4 another another DT cord-005646-xhx9pzhj 613 5 liver liver NN cord-005646-xhx9pzhj 613 6 transplant transplant NN cord-005646-xhx9pzhj 613 7 have have VBP cord-005646-xhx9pzhj 613 8 a a DT cord-005646-xhx9pzhj 613 9 markedly markedly RB cord-005646-xhx9pzhj 613 10 increased increase VBN cord-005646-xhx9pzhj 613 11 mortality mortality NN cord-005646-xhx9pzhj 613 12 . . . cord-005646-xhx9pzhj 614 1 Bleeding bleed VBG cord-005646-xhx9pzhj 614 2 and and CC cord-005646-xhx9pzhj 614 3 prolonged prolong VBN cord-005646-xhx9pzhj 614 4 ICU ICU NNP cord-005646-xhx9pzhj 614 5 stay stay NN cord-005646-xhx9pzhj 614 6 is be VBZ cord-005646-xhx9pzhj 614 7 not not RB cord-005646-xhx9pzhj 614 8 significantly significantly RB cord-005646-xhx9pzhj 614 9 different different JJ cord-005646-xhx9pzhj 614 10 between between IN cord-005646-xhx9pzhj 614 11 the the DT cord-005646-xhx9pzhj 614 12 first first JJ cord-005646-xhx9pzhj 614 13 and and CC cord-005646-xhx9pzhj 614 14 subsequent subsequent JJ cord-005646-xhx9pzhj 614 15 transplants transplant NNS cord-005646-xhx9pzhj 614 16 , , , cord-005646-xhx9pzhj 614 17 FULMINANT FULMINANT NNP cord-005646-xhx9pzhj 614 18 HEPATIC HEPATIC NNP cord-005646-xhx9pzhj 614 19 FAILURE failure NN cord-005646-xhx9pzhj 614 20 AND and CC cord-005646-xhx9pzhj 614 21 ORTOTHOPIC ORTOTHOPIC NNP cord-005646-xhx9pzhj 614 22 LIVER liver NN cord-005646-xhx9pzhj 614 23 TRANSPLANTATION.Dr TRANSPLANTATION.Dr NNP cord-005646-xhx9pzhj 614 24 . . . cord-005646-xhx9pzhj 615 1 Sasb6n Sasb6n NNS cord-005646-xhx9pzhj 615 2 , , , cord-005646-xhx9pzhj 615 3 J;Centeno J;Centeno NNP cord-005646-xhx9pzhj 615 4 , , , cord-005646-xhx9pzhj 615 5 M;Entin M;Entin NNP cord-005646-xhx9pzhj 615 6 , , , cord-005646-xhx9pzhj 615 7 E;Acarenza E;Acarenza NNP cord-005646-xhx9pzhj 615 8 , , , cord-005646-xhx9pzhj 615 9 M;Ciocca M;Ciocca NNP cord-005646-xhx9pzhj 615 10 , , , cord-005646-xhx9pzhj 615 11 M M NNP cord-005646-xhx9pzhj 615 12 : : : cord-005646-xhx9pzhj 615 13 Gofii Gofii NNP cord-005646-xhx9pzhj 615 14 , , , cord-005646-xhx9pzhj 615 15 J;Bianco J;Bianco NNP cord-005646-xhx9pzhj 615 16 , , , cord-005646-xhx9pzhj 615 17 G;Weller g;weller NN cord-005646-xhx9pzhj 615 18 , , , cord-005646-xhx9pzhj 615 19 G;Imventarza G;Imventarza NNP cord-005646-xhx9pzhj 615 20 , , , cord-005646-xhx9pzhj 615 21 O. O. NNP cord-005646-xhx9pzhj 615 22 Unidad Unidad NNP cord-005646-xhx9pzhj 615 23 de de NNP cord-005646-xhx9pzhj 615 24 Cuidados Cuidados NNP cord-005646-xhx9pzhj 615 25 Intensivos Intensivos NNP cord-005646-xhx9pzhj 615 26 . . . cord-005646-xhx9pzhj 616 1 Hospital hospital NN cord-005646-xhx9pzhj 616 2 de de NNP cord-005646-xhx9pzhj 616 3 Pediatria Pediatria NNP cord-005646-xhx9pzhj 616 4 " " '' cord-005646-xhx9pzhj 617 1 Dr. Dr. NNP cord-005646-xhx9pzhj 618 1 J.P. J.P. NNP cord-005646-xhx9pzhj 618 2 Garrahan"1245.Buenos Garrahan"1245.Buenos NNP cord-005646-xhx9pzhj 618 3 Aires Aires NNP cord-005646-xhx9pzhj 618 4 . . . cord-005646-xhx9pzhj 619 1 Argentina Argentina NNP cord-005646-xhx9pzhj 619 2 . . . cord-005646-xhx9pzhj 620 1 Introduction introduction NN cord-005646-xhx9pzhj 620 2 : : : cord-005646-xhx9pzhj 621 1 Fulminant Fulminant NNP cord-005646-xhx9pzhj 621 2 Hepatic Hepatic NNP cord-005646-xhx9pzhj 621 3 Failure Failure NNP cord-005646-xhx9pzhj 621 4 ( ( -LRB- cord-005646-xhx9pzhj 621 5 FHF FHF NNP cord-005646-xhx9pzhj 621 6 ) ) -RRB- cord-005646-xhx9pzhj 621 7 is be VBZ cord-005646-xhx9pzhj 621 8 a a DT cord-005646-xhx9pzhj 621 9 clinical clinical JJ cord-005646-xhx9pzhj 621 10 syndrome syndrome NN cord-005646-xhx9pzhj 621 11 , , , cord-005646-xhx9pzhj 621 12 defined define VBN cord-005646-xhx9pzhj 621 13 by by IN cord-005646-xhx9pzhj 621 14 the the DT cord-005646-xhx9pzhj 621 15 development development NN cord-005646-xhx9pzhj 621 16 of of IN cord-005646-xhx9pzhj 621 17 hepatic hepatic JJ cord-005646-xhx9pzhj 621 18 encefalopathy encefalopathy NNP cord-005646-xhx9pzhj 621 19 within within IN cord-005646-xhx9pzhj 621 20 8 8 CD cord-005646-xhx9pzhj 621 21 weeks week NNS cord-005646-xhx9pzhj 621 22 from from IN cord-005646-xhx9pzhj 621 23 onset onset NN cord-005646-xhx9pzhj 621 24 of of IN cord-005646-xhx9pzhj 621 25 illness illness NN cord-005646-xhx9pzhj 621 26 in in IN cord-005646-xhx9pzhj 621 27 a a DT cord-005646-xhx9pzhj 621 28 previously previously RB cord-005646-xhx9pzhj 621 29 healthy healthy JJ cord-005646-xhx9pzhj 621 30 person person NN cord-005646-xhx9pzhj 621 31 . . . cord-005646-xhx9pzhj 622 1 By by IN cord-005646-xhx9pzhj 622 2 far far RB cord-005646-xhx9pzhj 622 3 , , , cord-005646-xhx9pzhj 622 4 the the DT cord-005646-xhx9pzhj 622 5 most most RBS cord-005646-xhx9pzhj 622 6 comun comun JJ cord-005646-xhx9pzhj 622 7 cause cause NN cord-005646-xhx9pzhj 622 8 of of IN cord-005646-xhx9pzhj 622 9 pediatric pediatric JJ cord-005646-xhx9pzhj 622 10 FHF FHF NNP cord-005646-xhx9pzhj 622 11 in in IN cord-005646-xhx9pzhj 622 12 all all DT cord-005646-xhx9pzhj 622 13 series series NN cord-005646-xhx9pzhj 622 14 , , , cord-005646-xhx9pzhj 622 15 is be VBZ cord-005646-xhx9pzhj 622 16 acute acute JJ cord-005646-xhx9pzhj 622 17 viral viral JJ cord-005646-xhx9pzhj 622 18 hepatitis hepatitis NN cord-005646-xhx9pzhj 622 19 . . . cord-005646-xhx9pzhj 623 1 We -PRON- PRP cord-005646-xhx9pzhj 623 2 report report VBP cord-005646-xhx9pzhj 623 3 our -PRON- PRP$ cord-005646-xhx9pzhj 623 4 experiences experience NNS cord-005646-xhx9pzhj 623 5 with with IN cord-005646-xhx9pzhj 623 6 the the DT cord-005646-xhx9pzhj 623 7 pediatric pediatric JJ cord-005646-xhx9pzhj 623 8 FHF FHF NNP cord-005646-xhx9pzhj 623 9 and and CC cord-005646-xhx9pzhj 623 10 ortothopic ortothopic JJ cord-005646-xhx9pzhj 623 11 liver liver NN cord-005646-xhx9pzhj 623 12 transplantation transplantation NN cord-005646-xhx9pzhj 623 13 ( ( -LRB- cord-005646-xhx9pzhj 623 14 OLT OLT NNP cord-005646-xhx9pzhj 623 15 ) ) -RRB- cord-005646-xhx9pzhj 623 16 as as IN cord-005646-xhx9pzhj 623 17 attemative attemative JJ cord-005646-xhx9pzhj 623 18 of of IN cord-005646-xhx9pzhj 623 19 treatment treatment NN cord-005646-xhx9pzhj 623 20 . . . cord-005646-xhx9pzhj 624 1 Patients:30 patients:30 CD cord-005646-xhx9pzhj 624 2 childrens children NNS cord-005646-xhx9pzhj 624 3 with with IN cord-005646-xhx9pzhj 624 4 FHF FHF NNP cord-005646-xhx9pzhj 624 5 diagnosis diagnosis NN cord-005646-xhx9pzhj 624 6 were be VBD cord-005646-xhx9pzhj 624 7 admitted admit VBN cord-005646-xhx9pzhj 624 8 at at IN cord-005646-xhx9pzhj 624 9 the the DT cord-005646-xhx9pzhj 624 10 PICU PICU NNP cord-005646-xhx9pzhj 624 11 from from IN cord-005646-xhx9pzhj 624 12 1/1/1993 1/1/1993 CD cord-005646-xhx9pzhj 624 13 to to IN cord-005646-xhx9pzhj 624 14 1/12/1995.Symptomatic 1/12/1995.symptomatic CD cord-005646-xhx9pzhj 624 15 treatment treatment NN cord-005646-xhx9pzhj 624 16 was be VBD cord-005646-xhx9pzhj 624 17 given give VBN cord-005646-xhx9pzhj 624 18 to to IN cord-005646-xhx9pzhj 624 19 all all DT cord-005646-xhx9pzhj 624 20 children child NNS cord-005646-xhx9pzhj 624 21 and and CC cord-005646-xhx9pzhj 624 22 all all DT cord-005646-xhx9pzhj 624 23 were be VBD cord-005646-xhx9pzhj 624 24 put put VBN cord-005646-xhx9pzhj 624 25 on on IN cord-005646-xhx9pzhj 624 26 list list NN cord-005646-xhx9pzhj 624 27 for for IN cord-005646-xhx9pzhj 624 28 OLT OLT NNP cord-005646-xhx9pzhj 624 29 , , , cord-005646-xhx9pzhj 624 30 ) ) -RRB- cord-005646-xhx9pzhj 624 31 following follow VBG cord-005646-xhx9pzhj 624 32 the the DT cord-005646-xhx9pzhj 624 33 King King NNP cord-005646-xhx9pzhj 624 34 's 's POS cord-005646-xhx9pzhj 624 35 College College NNP cord-005646-xhx9pzhj 624 36 criterion criterion NN cord-005646-xhx9pzhj 624 37 ( ( -LRB- cord-005646-xhx9pzhj 624 38 Protrombina protrombina JJ cord-005646-xhx9pzhj 624 39 time time NN cord-005646-xhx9pzhj 624 40 , , , cord-005646-xhx9pzhj 624 41 age age NN cord-005646-xhx9pzhj 624 42 , , , cord-005646-xhx9pzhj 624 43 atiologies atiologie NNS cord-005646-xhx9pzhj 624 44 , , , cord-005646-xhx9pzhj 624 45 bilirrubin bilirrubin NNP cord-005646-xhx9pzhj 624 46 , , , cord-005646-xhx9pzhj 624 47 and and CC cord-005646-xhx9pzhj 624 48 encefalopathy encefalopathy NNP cord-005646-xhx9pzhj 624 49 state state NNP cord-005646-xhx9pzhj 624 50 ) ) -RRB- cord-005646-xhx9pzhj 624 51 . . . cord-005646-xhx9pzhj 625 1 Results result NNS cord-005646-xhx9pzhj 625 2 : : : cord-005646-xhx9pzhj 626 1 Etiologic Etiologic NNP cord-005646-xhx9pzhj 626 2 causes cause NNS cord-005646-xhx9pzhj 626 3 corresponded correspond VBD cord-005646-xhx9pzhj 626 4 to to IN cord-005646-xhx9pzhj 626 5 the the DT cord-005646-xhx9pzhj 626 6 30 30 CD cord-005646-xhx9pzhj 626 7 childrens children NNS cord-005646-xhx9pzhj 626 8 were:23 were:23 NNS cord-005646-xhx9pzhj 626 9 , , , cord-005646-xhx9pzhj 626 10 HAV HAV NNP cord-005646-xhx9pzhj 626 11 ( ( -LRB- cord-005646-xhx9pzhj 626 12 76 76 CD cord-005646-xhx9pzhj 626 13 % % NN cord-005646-xhx9pzhj 626 14 ) ) -RRB- cord-005646-xhx9pzhj 626 15 ; ; : cord-005646-xhx9pzhj 626 16 6 6 CD cord-005646-xhx9pzhj 626 17 , , , cord-005646-xhx9pzhj 626 18 NoA NoA NNP cord-005646-xhx9pzhj 626 19 NoB NoB NNP cord-005646-xhx9pzhj 626 20 ( ( -LRB- cord-005646-xhx9pzhj 626 21 20%);1 20%);1 CD cord-005646-xhx9pzhj 626 22 , , , cord-005646-xhx9pzhj 626 23 autoinmune autoinmune NNP cord-005646-xhx9pzhj 626 24 ( ( -LRB- cord-005646-xhx9pzhj 626 25 4%).The 4%).the CD cord-005646-xhx9pzhj 626 26 age age NN cord-005646-xhx9pzhj 626 27 was be VBD cord-005646-xhx9pzhj 626 28 mean:4 mean:4 NNP cord-005646-xhx9pzhj 626 29 years year NNS cord-005646-xhx9pzhj 626 30 ( ( -LRB- cord-005646-xhx9pzhj 626 31 Range:16 range:16 NN cord-005646-xhx9pzhj 626 32 month-10 month-10 CD cord-005646-xhx9pzhj 626 33 years).Seventeen years).seventeen JJ cord-005646-xhx9pzhj 626 34 patients patient NNS cord-005646-xhx9pzhj 626 35 were be VBD cord-005646-xhx9pzhj 626 36 transplanted,13 transplanted,13 NNP cord-005646-xhx9pzhj 626 37 chidmn chidmn NNP cord-005646-xhx9pzhj 626 38 were be VBD cord-005646-xhx9pzhj 626 39 discarded discard VBN cord-005646-xhx9pzhj 626 40 because because IN cord-005646-xhx9pzhj 626 41 : : : cord-005646-xhx9pzhj 626 42 no no DT cord-005646-xhx9pzhj 626 43 donors:5;withdrow donors:5;withdrow NN cord-005646-xhx9pzhj 626 44 of of IN cord-005646-xhx9pzhj 626 45 the the DT cord-005646-xhx9pzhj 626 46 list:3,because list:3,because NNP cord-005646-xhx9pzhj 626 47 sepsis sepsis NN cord-005646-xhx9pzhj 626 48 in in IN cord-005646-xhx9pzhj 626 49 2 2 CD cord-005646-xhx9pzhj 626 50 and and CC cord-005646-xhx9pzhj 626 51 bleeding bleeding NN cord-005646-xhx9pzhj 626 52 of of IN cord-005646-xhx9pzhj 626 53 CNS CNS NNP cord-005646-xhx9pzhj 626 54 1;and 1;and CD cord-005646-xhx9pzhj 627 1 no no DT cord-005646-xhx9pzhj 627 2 admission admission NN cord-005646-xhx9pzhj 627 3 at at IN cord-005646-xhx9pzhj 627 4 list:5 list:5 NNP cord-005646-xhx9pzhj 627 5 because because IN cord-005646-xhx9pzhj 627 6 genetic genetic JJ cord-005646-xhx9pzhj 627 7 syndrome syndrome NN cord-005646-xhx9pzhj 627 8 1 1 CD cord-005646-xhx9pzhj 627 9 , , , cord-005646-xhx9pzhj 627 10 massive massive JJ cord-005646-xhx9pzhj 627 11 intestinal intestinal JJ cord-005646-xhx9pzhj 627 12 necrosis necrosis NN cord-005646-xhx9pzhj 627 13 , , , cord-005646-xhx9pzhj 627 14 1 1 CD cord-005646-xhx9pzhj 627 15 , , , cord-005646-xhx9pzhj 627 16 mitral mitral JJ cord-005646-xhx9pzhj 627 17 valvulopathy valvulopathy NNP cord-005646-xhx9pzhj 627 18 1 1 CD cord-005646-xhx9pzhj 627 19 and and CC cord-005646-xhx9pzhj 627 20 sepsis,2 sepsis,2 CD cord-005646-xhx9pzhj 627 21 . . . cord-005646-xhx9pzhj 628 1 25 25 CD cord-005646-xhx9pzhj 628 2 patients patient NNS cord-005646-xhx9pzhj 628 3 ( ( -LRB- cord-005646-xhx9pzhj 628 4 86 86 CD cord-005646-xhx9pzhj 628 5 % % NN cord-005646-xhx9pzhj 628 6 ) ) -RRB- cord-005646-xhx9pzhj 628 7 had have VBD cord-005646-xhx9pzhj 628 8 at at RB cord-005646-xhx9pzhj 628 9 least least RBS cord-005646-xhx9pzhj 628 10 one one CD cord-005646-xhx9pzhj 628 11 complication complication NN cord-005646-xhx9pzhj 628 12 dudng dudng NNP cord-005646-xhx9pzhj 628 13 the the DT cord-005646-xhx9pzhj 628 14 post post JJ cord-005646-xhx9pzhj 628 15 operative operative JJ cord-005646-xhx9pzhj 628 16 period period NN cord-005646-xhx9pzhj 628 17 . . . cord-005646-xhx9pzhj 629 1 The the DT cord-005646-xhx9pzhj 629 2 most most RBS cord-005646-xhx9pzhj 629 3 frequent frequent JJ cord-005646-xhx9pzhj 629 4 was be VBD cord-005646-xhx9pzhj 629 5 the the DT cord-005646-xhx9pzhj 629 6 acute acute JJ cord-005646-xhx9pzhj 629 7 renal renal JJ cord-005646-xhx9pzhj 629 8 insufficiency(ARI insufficiency(ari NN cord-005646-xhx9pzhj 629 9 ) ) -RRB- cord-005646-xhx9pzhj 629 10 and and CC cord-005646-xhx9pzhj 629 11 4 4 CD cord-005646-xhx9pzhj 629 12 patients patient NNS cord-005646-xhx9pzhj 629 13 requiered requiere VBN cord-005646-xhx9pzhj 629 14 continuos continuos NNP cord-005646-xhx9pzhj 629 15 hemofiltration hemofiltration NN cord-005646-xhx9pzhj 629 16 . . . cord-005646-xhx9pzhj 630 1 The the DT cord-005646-xhx9pzhj 630 2 gtobal gtobal JJ cord-005646-xhx9pzhj 630 3 mortality mortality NN cord-005646-xhx9pzhj 630 4 rate rate NN cord-005646-xhx9pzhj 630 5 was be VBD cord-005646-xhx9pzhj 630 6 75%.The 75%.the CD cord-005646-xhx9pzhj 630 7 mortality mortality NN cord-005646-xhx9pzhj 630 8 of of IN cord-005646-xhx9pzhj 630 9 patients patient NNS cord-005646-xhx9pzhj 630 10 without without IN cord-005646-xhx9pzhj 630 11 OLT OLT NNP cord-005646-xhx9pzhj 630 12 was be VBD cord-005646-xhx9pzhj 630 13 100 100 CD cord-005646-xhx9pzhj 630 14 % % NN cord-005646-xhx9pzhj 630 15 and and CC cord-005646-xhx9pzhj 630 16 the the DT cord-005646-xhx9pzhj 630 17 mortality mortality NN cord-005646-xhx9pzhj 630 18 of of IN cord-005646-xhx9pzhj 630 19 patients patient NNS cord-005646-xhx9pzhj 630 20 with with IN cord-005646-xhx9pzhj 630 21 OLT OLT NNP cord-005646-xhx9pzhj 630 22 was be VBD cord-005646-xhx9pzhj 630 23 41%,4 41%,4 CD cord-005646-xhx9pzhj 630 24 patients patient NNS cord-005646-xhx9pzhj 630 25 dayed daye VBN cord-005646-xhx9pzhj 630 26 because because IN cord-005646-xhx9pzhj 630 27 sepsis sepsis NN cord-005646-xhx9pzhj 630 28 , , , cord-005646-xhx9pzhj 630 29 ( ( -LRB- cord-005646-xhx9pzhj 630 30 2 2 CD cord-005646-xhx9pzhj 630 31 candidiasis candidiasis NN cord-005646-xhx9pzhj 630 32 ) ) -RRB- cord-005646-xhx9pzhj 630 33 and and CC cord-005646-xhx9pzhj 630 34 the the DT cord-005646-xhx9pzhj 630 35 others other NNS cord-005646-xhx9pzhj 630 36 3 3 CD cord-005646-xhx9pzhj 630 37 because because IN cord-005646-xhx9pzhj 630 38 MOF.The MOF.The NNP cord-005646-xhx9pzhj 630 39 actuarial actuarial JJ cord-005646-xhx9pzhj 630 40 survival survival NN cord-005646-xhx9pzhj 630 41 at at IN cord-005646-xhx9pzhj 630 42 1 1 CD cord-005646-xhx9pzhj 630 43 year year NN cord-005646-xhx9pzhj 630 44 is be VBZ cord-005646-xhx9pzhj 630 45 54 54 CD cord-005646-xhx9pzhj 630 46 % % NN cord-005646-xhx9pzhj 630 47 and and CC cord-005646-xhx9pzhj 630 48 the the DT cord-005646-xhx9pzhj 630 49 follow follow NN cord-005646-xhx9pzhj 630 50 up up IN cord-005646-xhx9pzhj 630 51 of of IN cord-005646-xhx9pzhj 630 52 8 8 CD cord-005646-xhx9pzhj 630 53 months month NNS cord-005646-xhx9pzhj 630 54 . . . cord-005646-xhx9pzhj 631 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 631 2 : : : cord-005646-xhx9pzhj 632 1 The the DT cord-005646-xhx9pzhj 632 2 FHF FHF NNP cord-005646-xhx9pzhj 632 3 is be VBZ cord-005646-xhx9pzhj 632 4 a a DT cord-005646-xhx9pzhj 632 5 very very RB cord-005646-xhx9pzhj 632 6 severe severe JJ cord-005646-xhx9pzhj 632 7 and and CC cord-005646-xhx9pzhj 632 8 frequent frequent JJ cord-005646-xhx9pzhj 632 9 disease disease NN cord-005646-xhx9pzhj 632 10 at at IN cord-005646-xhx9pzhj 632 11 PICU PICU NNP cord-005646-xhx9pzhj 632 12 . . . cord-005646-xhx9pzhj 633 1 Supportive supportive JJ cord-005646-xhx9pzhj 633 2 treatment treatment NN cord-005646-xhx9pzhj 633 3 only only RB cord-005646-xhx9pzhj 633 4 is be VBZ cord-005646-xhx9pzhj 633 5 associated associate VBN cord-005646-xhx9pzhj 633 6 with with IN cord-005646-xhx9pzhj 633 7 a a DT cord-005646-xhx9pzhj 633 8 very very RB cord-005646-xhx9pzhj 633 9 poor poor JJ cord-005646-xhx9pzhj 633 10 prognosis prognosis NN cord-005646-xhx9pzhj 633 11 and and CC cord-005646-xhx9pzhj 633 12 high high JJ cord-005646-xhx9pzhj 633 13 mortality mortality NN cord-005646-xhx9pzhj 633 14 rate rate NN cord-005646-xhx9pzhj 633 15 . . . cord-005646-xhx9pzhj 634 1 The the DT cord-005646-xhx9pzhj 634 2 most most RBS cord-005646-xhx9pzhj 634 3 frequent frequent JJ cord-005646-xhx9pzhj 634 4 etiology etiology NN cord-005646-xhx9pzhj 634 5 in in IN cord-005646-xhx9pzhj 634 6 our -PRON- PRP$ cord-005646-xhx9pzhj 634 7 country country NN cord-005646-xhx9pzhj 634 8 is be VBZ cord-005646-xhx9pzhj 634 9 the the DT cord-005646-xhx9pzhj 634 10 HAV HAV NNP cord-005646-xhx9pzhj 634 11 . . . cord-005646-xhx9pzhj 635 1 The the DT cord-005646-xhx9pzhj 635 2 OLT OLT NNP cord-005646-xhx9pzhj 635 3 is be VBZ cord-005646-xhx9pzhj 635 4 applicable applicable JJ cord-005646-xhx9pzhj 635 5 in in IN cord-005646-xhx9pzhj 635 6 this this DT cord-005646-xhx9pzhj 635 7 cases case NNS cord-005646-xhx9pzhj 635 8 and and CC cord-005646-xhx9pzhj 635 9 is be VBZ cord-005646-xhx9pzhj 635 10 a a DT cord-005646-xhx9pzhj 635 11 valid valid JJ cord-005646-xhx9pzhj 635 12 alternative alternative NN cord-005646-xhx9pzhj 635 13 of of IN cord-005646-xhx9pzhj 635 14 treatment treatment NN cord-005646-xhx9pzhj 635 15 ( ( -LRB- cord-005646-xhx9pzhj 635 16 mortality mortality NN cord-005646-xhx9pzhj 635 17 in in IN cord-005646-xhx9pzhj 635 18 our -PRON- PRP$ cord-005646-xhx9pzhj 635 19 series series NN cord-005646-xhx9pzhj 635 20 41%).The 41%).the CD cord-005646-xhx9pzhj 636 1 ARI ARI NNP cord-005646-xhx9pzhj 636 2 is be VBZ cord-005646-xhx9pzhj 636 3 the the DT cord-005646-xhx9pzhj 636 4 most most RBS cord-005646-xhx9pzhj 636 5 frequent frequent JJ cord-005646-xhx9pzhj 636 6 complication complication NN cord-005646-xhx9pzhj 636 7 during during IN cord-005646-xhx9pzhj 636 8 the the DT cord-005646-xhx9pzhj 636 9 post post AFX cord-005646-xhx9pzhj 636 10 opeative opeative NN cord-005646-xhx9pzhj 636 11 period period NN cord-005646-xhx9pzhj 636 12 . . . cord-005646-xhx9pzhj 637 1 In in IN cord-005646-xhx9pzhj 637 2 Argentina Argentina NNP cord-005646-xhx9pzhj 637 3 , , , cord-005646-xhx9pzhj 637 4 due due JJ cord-005646-xhx9pzhj 637 5 the the DT cord-005646-xhx9pzhj 637 6 high high JJ cord-005646-xhx9pzhj 637 7 prevalence prevalence NN cord-005646-xhx9pzhj 637 8 of of IN cord-005646-xhx9pzhj 637 9 HAV HAV NNP cord-005646-xhx9pzhj 637 10 , , , cord-005646-xhx9pzhj 637 11 prevention prevention NN cord-005646-xhx9pzhj 637 12 must must MD cord-005646-xhx9pzhj 637 13 be be VB cord-005646-xhx9pzhj 637 14 considered consider VBN cord-005646-xhx9pzhj 637 15 the the DT cord-005646-xhx9pzhj 637 16 main main JJ cord-005646-xhx9pzhj 637 17 and and CC cord-005646-xhx9pzhj 637 18 only only JJ cord-005646-xhx9pzhj 637 19 way way NN cord-005646-xhx9pzhj 637 20 to to TO cord-005646-xhx9pzhj 637 21 avoid avoid VB cord-005646-xhx9pzhj 637 22 this this DT cord-005646-xhx9pzhj 637 23 catastrophic catastrophic JJ cord-005646-xhx9pzhj 637 24 illness.- illness.- NNP cord-005646-xhx9pzhj 637 25 To to TO cord-005646-xhx9pzhj 637 26 assess assess VB cord-005646-xhx9pzhj 637 27 the the DT cord-005646-xhx9pzhj 637 28 efficacy efficacy NN cord-005646-xhx9pzhj 637 29 of of IN cord-005646-xhx9pzhj 637 30 gastric gastric JJ cord-005646-xhx9pzhj 637 31 intramucosal intramucosal NN cord-005646-xhx9pzhj 637 32 pH pH NNP cord-005646-xhx9pzhj 637 33 ( ( -LRB- cord-005646-xhx9pzhj 637 34 pHi pHi NNP cord-005646-xhx9pzhj 637 35 ) ) -RRB- cord-005646-xhx9pzhj 637 36 for for IN cord-005646-xhx9pzhj 637 37 evaluation evaluation NN cord-005646-xhx9pzhj 637 38 of of IN cord-005646-xhx9pzhj 637 39 tissular tissular JJ cord-005646-xhx9pzhj 637 40 perfusion perfusion NN cord-005646-xhx9pzhj 637 41 and and CC cord-005646-xhx9pzhj 637 42 prediction prediction NN cord-005646-xhx9pzhj 637 43 of of IN cord-005646-xhx9pzhj 637 44 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 637 45 complications complication NNS cord-005646-xhx9pzhj 637 46 m m LS cord-005646-xhx9pzhj 637 47 critically critically RB cord-005646-xhx9pzhj 637 48 ill ill JJ cord-005646-xhx9pzhj 637 49 children child NNS cord-005646-xhx9pzhj 637 50 . . . cord-005646-xhx9pzhj 638 1 PATIENTS patient NNS cord-005646-xhx9pzhj 638 2 AND and CC cord-005646-xhx9pzhj 638 3 METHODS method NNS cord-005646-xhx9pzhj 638 4 : : : cord-005646-xhx9pzhj 639 1 Thirty thirty CD cord-005646-xhx9pzhj 639 2 critically critically RB cord-005646-xhx9pzhj 639 3 ill ill JJ cord-005646-xhx9pzhj 639 4 children child NNS cord-005646-xhx9pzhj 639 5 ( ( -LRB- cord-005646-xhx9pzhj 639 6 16 16 CD cord-005646-xhx9pzhj 639 7 boys boy NNS cord-005646-xhx9pzhj 639 8 and and CC cord-005646-xhx9pzhj 639 9 14 14 CD cord-005646-xhx9pzhj 639 10 girls girl NNS cord-005646-xhx9pzhj 639 11 ) ) -RRB- cord-005646-xhx9pzhj 639 12 whose whose WP$ cord-005646-xhx9pzhj 639 13 age age NN cord-005646-xhx9pzhj 639 14 ranged range VBD cord-005646-xhx9pzhj 639 15 from from IN cord-005646-xhx9pzhj 639 16 3 3 CD cord-005646-xhx9pzhj 639 17 month month NN cord-005646-xhx9pzhj 639 18 and and CC cord-005646-xhx9pzhj 639 19 12 12 CD cord-005646-xhx9pzhj 639 20 years year NNS cord-005646-xhx9pzhj 639 21 old old JJ cord-005646-xhx9pzhj 639 22 were be VBD cord-005646-xhx9pzhj 639 23 studied study VBN cord-005646-xhx9pzhj 639 24 . . . cord-005646-xhx9pzhj 640 1 A a DT cord-005646-xhx9pzhj 640 2 tonometry tonometry NN cord-005646-xhx9pzhj 640 3 catheter catheter NN cord-005646-xhx9pzhj 640 4 was be VBD cord-005646-xhx9pzhj 640 5 placed place VBN cord-005646-xhx9pzhj 640 6 in in IN cord-005646-xhx9pzhj 640 7 the the DT cord-005646-xhx9pzhj 640 8 stomach stomach NN cord-005646-xhx9pzhj 640 9 of of IN cord-005646-xhx9pzhj 640 10 all all DT cord-005646-xhx9pzhj 640 11 patients patient NNS cord-005646-xhx9pzhj 640 12 at at IN cord-005646-xhx9pzhj 640 13 their -PRON- PRP$ cord-005646-xhx9pzhj 640 14 ° ° NN cord-005646-xhx9pzhj 640 15 admission admission NN cord-005646-xhx9pzhj 640 16 in in IN cord-005646-xhx9pzhj 640 17 Pediatric Pediatric NNP cord-005646-xhx9pzhj 640 18 ICU ICU NNP cord-005646-xhx9pzhj 640 19 . . . cord-005646-xhx9pzhj 641 1 Intramucosal Intramucosal NNP cord-005646-xhx9pzhj 641 2 pH ph NN cord-005646-xhx9pzhj 641 3 measures measure NNS cord-005646-xhx9pzhj 641 4 were be VBD cord-005646-xhx9pzhj 641 5 made make VBN cord-005646-xhx9pzhj 641 6 at at IN cord-005646-xhx9pzhj 641 7 the the DT cord-005646-xhx9pzhj 641 8 admission admission NN cord-005646-xhx9pzhj 641 9 and and CC cord-005646-xhx9pzhj 641 10 each each DT cord-005646-xhx9pzhj 641 11 6 6 CD cord-005646-xhx9pzhj 641 12 - - SYM cord-005646-xhx9pzhj 641 13 12 12 CD cord-005646-xhx9pzhj 641 14 hours hour NNS cord-005646-xhx9pzhj 641 15 during during IN cord-005646-xhx9pzhj 641 16 the the DT cord-005646-xhx9pzhj 641 17 study study NN cord-005646-xhx9pzhj 641 18 : : : cord-005646-xhx9pzhj 641 19 a a DT cord-005646-xhx9pzhj 641 20 total total NN cord-005646-xhx9pzhj 641 21 of of IN cord-005646-xhx9pzhj 641 22 202 202 CD cord-005646-xhx9pzhj 641 23 determinations determination NNS cord-005646-xhx9pzhj 641 24 were be VBD cord-005646-xhx9pzhj 641 25 made make VBN cord-005646-xhx9pzhj 641 26 . . . cord-005646-xhx9pzhj 642 1 The the DT cord-005646-xhx9pzhj 642 2 catheter catheter NN cord-005646-xhx9pzhj 642 3 was be VBD cord-005646-xhx9pzhj 642 4 removed remove VBN cord-005646-xhx9pzhj 642 5 after after IN cord-005646-xhx9pzhj 642 6 extubation extubation NN cord-005646-xhx9pzhj 642 7 and/or and/or CC cord-005646-xhx9pzhj 642 8 checking checking NN cord-005646-xhx9pzhj 642 9 of of IN cord-005646-xhx9pzhj 642 10 hemodyrmmic hemodyrmmic JJ cord-005646-xhx9pzhj 642 11 stability stability NN cord-005646-xhx9pzhj 642 12 of of IN cord-005646-xhx9pzhj 642 13 the the DT cord-005646-xhx9pzhj 642 14 patient patient NN cord-005646-xhx9pzhj 642 15 . . . cord-005646-xhx9pzhj 643 1 The the DT cord-005646-xhx9pzhj 643 2 intramucosal intramucosal NN cord-005646-xhx9pzhj 643 3 pH pH NNP cord-005646-xhx9pzhj 643 4 was be VBD cord-005646-xhx9pzhj 643 5 derived derive VBN cord-005646-xhx9pzhj 643 6 from from IN cord-005646-xhx9pzhj 643 7 application application NN cord-005646-xhx9pzhj 643 8 of of IN cord-005646-xhx9pzhj 643 9 the the DT cord-005646-xhx9pzhj 643 10 Henderson Henderson NNP cord-005646-xhx9pzhj 643 11 - - HYPH cord-005646-xhx9pzhj 643 12 Hasselbaeh Hasselbaeh NNP cord-005646-xhx9pzhj 643 13 formula formula NN cord-005646-xhx9pzhj 643 14 using use VBG cord-005646-xhx9pzhj 643 15 the the DT cord-005646-xhx9pzhj 643 16 pCO2 pCO2 NNP cord-005646-xhx9pzhj 643 17 value value NN cord-005646-xhx9pzhj 643 18 from from IN cord-005646-xhx9pzhj 643 19 the the DT cord-005646-xhx9pzhj 643 20 tonometer tonometer NN cord-005646-xhx9pzhj 643 21 and and CC cord-005646-xhx9pzhj 643 22 the the DT cord-005646-xhx9pzhj 643 23 arterial arterial JJ cord-005646-xhx9pzhj 643 24 bicarbonate bicarbonate NN cord-005646-xhx9pzhj 643 25 . . . cord-005646-xhx9pzhj 644 1 Values value NNS cord-005646-xhx9pzhj 644 2 of of IN cord-005646-xhx9pzhj 644 3 pHi pHi NNS cord-005646-xhx9pzhj 644 4 between between IN cord-005646-xhx9pzhj 644 5 7.30 7.30 CD cord-005646-xhx9pzhj 644 6 and and CC cord-005646-xhx9pzhj 644 7 7.45 7.45 CD cord-005646-xhx9pzhj 644 8 were be VBD cord-005646-xhx9pzhj 644 9 considered consider VBN cord-005646-xhx9pzhj 644 10 normal normal JJ cord-005646-xhx9pzhj 644 11 . . . cord-005646-xhx9pzhj 645 1 The the DT cord-005646-xhx9pzhj 645 2 relationship relationship NN cord-005646-xhx9pzhj 645 3 between between IN cord-005646-xhx9pzhj 645 4 pHi pHi NNS cord-005646-xhx9pzhj 645 5 and and CC cord-005646-xhx9pzhj 645 6 severity severity NN cord-005646-xhx9pzhj 645 7 of of IN cord-005646-xhx9pzhj 645 8 patient patient NN cord-005646-xhx9pzhj 645 9 measured measure VBN cord-005646-xhx9pzhj 645 10 through through IN cord-005646-xhx9pzhj 645 11 PRISM PRISM NNP cord-005646-xhx9pzhj 645 12 , , , cord-005646-xhx9pzhj 645 13 presence presence NN cord-005646-xhx9pzhj 645 14 of of IN cord-005646-xhx9pzhj 645 15 major major JJ cord-005646-xhx9pzhj 645 16 ( ( -LRB- cord-005646-xhx9pzhj 645 17 cardiorespiratory cardiorespiratory JJ cord-005646-xhx9pzhj 645 18 arrest arrest NN cord-005646-xhx9pzhj 645 19 , , , cord-005646-xhx9pzhj 645 20 shock shock NN cord-005646-xhx9pzhj 645 21 ) ) -RRB- cord-005646-xhx9pzhj 645 22 and and CC cord-005646-xhx9pzhj 645 23 minor minor JJ cord-005646-xhx9pzhj 645 24 ( ( -LRB- cord-005646-xhx9pzhj 645 25 hypotension hypotension NN cord-005646-xhx9pzhj 645 26 , , , cord-005646-xhx9pzhj 645 27 hypovolemia hypovolemia NN cord-005646-xhx9pzhj 645 28 or or CC cord-005646-xhx9pzhj 645 29 arrhytlmtias arrhytlmtias NNP cord-005646-xhx9pzhj 645 30 ) ) -RRB- cord-005646-xhx9pzhj 645 31 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 645 32 complications complication NNS cord-005646-xhx9pzhj 645 33 , , , cord-005646-xhx9pzhj 645 34 mortality mortality NN cord-005646-xhx9pzhj 645 35 and and CC cord-005646-xhx9pzhj 645 36 stay stay VB cord-005646-xhx9pzhj 645 37 in in IN cord-005646-xhx9pzhj 645 38 the the DT cord-005646-xhx9pzhj 645 39 PICU PICU NNP cord-005646-xhx9pzhj 645 40 , , , cord-005646-xhx9pzhj 645 41 was be VBD cord-005646-xhx9pzhj 645 42 analysed analyse VBN cord-005646-xhx9pzhj 645 43 . . . cord-005646-xhx9pzhj 646 1 RESULTS result NNS cord-005646-xhx9pzhj 646 2 : : : cord-005646-xhx9pzhj 647 1 The the DT cord-005646-xhx9pzhj 647 2 admission admission NN cord-005646-xhx9pzhj 647 3 value value NN cord-005646-xhx9pzhj 647 4 of of IN cord-005646-xhx9pzhj 647 5 pHi pHi NNS cord-005646-xhx9pzhj 647 6 was be VBD cord-005646-xhx9pzhj 647 7 7.48 7.48 CD cord-005646-xhx9pzhj 647 8 -t-0.15 -t-0.15 JJR cord-005646-xhx9pzhj 648 1 ( ( -LRB- cord-005646-xhx9pzhj 648 2 range range VBP cord-005646-xhx9pzhj 648 3 7.04 7.04 CD cord-005646-xhx9pzhj 648 4 - - HYPH cord-005646-xhx9pzhj 648 5 7.68 7.68 CD cord-005646-xhx9pzhj 648 6 ) ) -RRB- cord-005646-xhx9pzhj 648 7 . . . cord-005646-xhx9pzhj 649 1 Five five CD cord-005646-xhx9pzhj 649 2 patients patient NNS cord-005646-xhx9pzhj 649 3 ( ( -LRB- cord-005646-xhx9pzhj 649 4 16 16 CD cord-005646-xhx9pzhj 649 5 % % NN cord-005646-xhx9pzhj 649 6 ) ) -RRB- cord-005646-xhx9pzhj 649 7 had have VBD cord-005646-xhx9pzhj 649 8 an an DT cord-005646-xhx9pzhj 649 9 admission admission NN cord-005646-xhx9pzhj 649 10 pHi phi JJ cord-005646-xhx9pzhj 649 11 < < XX cord-005646-xhx9pzhj 649 12 7.30 7.30 CD cord-005646-xhx9pzhj 649 13 . . . cord-005646-xhx9pzhj 650 1 No no DT cord-005646-xhx9pzhj 650 2 relationship relationship NN cord-005646-xhx9pzhj 650 3 was be VBD cord-005646-xhx9pzhj 650 4 found find VBN cord-005646-xhx9pzhj 650 5 between between IN cord-005646-xhx9pzhj 650 6 an an DT cord-005646-xhx9pzhj 650 7 admission admission NN cord-005646-xhx9pzhj 650 8 pHi pHi VBZ cord-005646-xhx9pzhj 650 9 < < XX cord-005646-xhx9pzhj 650 10 7.30 7.30 CD cord-005646-xhx9pzhj 650 11 and and CC cord-005646-xhx9pzhj 650 12 a a DT cord-005646-xhx9pzhj 650 13 higher high JJR cord-005646-xhx9pzhj 650 14 incidence incidence NN cord-005646-xhx9pzhj 650 15 of of IN cord-005646-xhx9pzhj 650 16 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 650 17 complications complication NNS cord-005646-xhx9pzhj 650 18 . . . cord-005646-xhx9pzhj 651 1 Sixteen sixteen CD cord-005646-xhx9pzhj 651 2 patients patient NNS cord-005646-xhx9pzhj 651 3 ( ( -LRB- cord-005646-xhx9pzhj 651 4 53 53 CD cord-005646-xhx9pzhj 651 5 % % NN cord-005646-xhx9pzhj 651 6 ) ) -RRB- cord-005646-xhx9pzhj 651 7 showed show VBD cord-005646-xhx9pzhj 651 8 some some DT cord-005646-xhx9pzhj 651 9 values value NNS cord-005646-xhx9pzhj 651 10 of of IN cord-005646-xhx9pzhj 651 11 pHi pHi NNS cord-005646-xhx9pzhj 651 12 < < XX cord-005646-xhx9pzhj 651 13 730 730 CD cord-005646-xhx9pzhj 651 14 during during IN cord-005646-xhx9pzhj 651 15 their -PRON- PRP$ cord-005646-xhx9pzhj 651 16 evolution evolution NN cord-005646-xhx9pzhj 651 17 . . . cord-005646-xhx9pzhj 652 1 Patients patient NNS cord-005646-xhx9pzhj 652 2 with with IN cord-005646-xhx9pzhj 652 3 pHi pHi NNP cord-005646-xhx9pzhj 652 4 < < XX cord-005646-xhx9pzhj 652 5 7.30 7.30 CD cord-005646-xhx9pzhj 652 6 had have VBD cord-005646-xhx9pzhj 652 7 a a DT cord-005646-xhx9pzhj 652 8 higher high JJR cord-005646-xhx9pzhj 652 9 number number NN cord-005646-xhx9pzhj 652 10 of of IN cord-005646-xhx9pzhj 652 11 hemodynanuc hemodynanuc NN cord-005646-xhx9pzhj 652 12 complications complication NNS cord-005646-xhx9pzhj 652 13 than than IN cord-005646-xhx9pzhj 652 14 the the DT cord-005646-xhx9pzhj 652 15 rest rest NN cord-005646-xhx9pzhj 652 16 ( ( -LRB- cord-005646-xhx9pzhj 652 17 p p NN cord-005646-xhx9pzhj 652 18 < < XX cord-005646-xhx9pzhj 652 19 0.0001 0.0001 CD cord-005646-xhx9pzhj 652 20 ) ) -RRB- cord-005646-xhx9pzhj 652 21 . . . cord-005646-xhx9pzhj 653 1 Every every DT cord-005646-xhx9pzhj 653 2 cardiorespiratory cardiorespiratory JJ cord-005646-xhx9pzhj 653 3 arrest arrest NN cord-005646-xhx9pzhj 653 4 ( ( -LRB- cord-005646-xhx9pzhj 653 5 CRA CRA NNP cord-005646-xhx9pzhj 653 6 ) ) -RRB- cord-005646-xhx9pzhj 653 7 and and CC cord-005646-xhx9pzhj 653 8 shock shock NN cord-005646-xhx9pzhj 653 9 cases case NNS cord-005646-xhx9pzhj 653 10 were be VBD cord-005646-xhx9pzhj 653 11 related relate VBN cord-005646-xhx9pzhj 653 12 to to IN cord-005646-xhx9pzhj 653 13 a a DT cord-005646-xhx9pzhj 653 14 pHi phi JJ cord-005646-xhx9pzhj 653 15 < < XX cord-005646-xhx9pzhj 653 16 7.30 7.30 CD cord-005646-xhx9pzhj 653 17 . . . cord-005646-xhx9pzhj 654 1 Patients patient NNS cord-005646-xhx9pzhj 654 2 with with IN cord-005646-xhx9pzhj 654 3 major major JJ cord-005646-xhx9pzhj 654 4 complications complication NNS cord-005646-xhx9pzhj 654 5 ( ( -LRB- cord-005646-xhx9pzhj 654 6 CRA cra NN cord-005646-xhx9pzhj 654 7 and and CC cord-005646-xhx9pzhj 654 8 shock shock NN cord-005646-xhx9pzhj 654 9 ) ) -RRB- cord-005646-xhx9pzhj 654 10 had have VBD cord-005646-xhx9pzhj 654 11 a a DT cord-005646-xhx9pzhj 654 12 pHi phi JJ cord-005646-xhx9pzhj 654 13 lower lower RBR cord-005646-xhx9pzhj 654 14 ( ( -LRB- cord-005646-xhx9pzhj 654 15 p= p= JJ cord-005646-xhx9pzhj 654 16 0.03 0.03 CD cord-005646-xhx9pzhj 654 17 ) ) -RRB- cord-005646-xhx9pzhj 654 18 , , , cord-005646-xhx9pzhj 654 19 as as RB cord-005646-xhx9pzhj 654 20 well well RB cord-005646-xhx9pzhj 654 21 as as IN cord-005646-xhx9pzhj 654 22 a a DT cord-005646-xhx9pzhj 654 23 higher high JJR cord-005646-xhx9pzhj 654 24 number number NN cord-005646-xhx9pzhj 654 25 of of IN cord-005646-xhx9pzhj 654 26 measurements measurement NNS cord-005646-xhx9pzhj 654 27 of of IN cord-005646-xhx9pzhj 654 28 low low JJ cord-005646-xhx9pzhj 654 29 phi phi NN cord-005646-xhx9pzhj 654 30 ( ( -LRB- cord-005646-xhx9pzhj 654 31 p= p= NNP cord-005646-xhx9pzhj 654 32 0.003 0.003 CD cord-005646-xhx9pzhj 654 33 ) ) -RRB- cord-005646-xhx9pzhj 654 34 than than IN cord-005646-xhx9pzhj 654 35 patients patient NNS cord-005646-xhx9pzhj 654 36 with with IN cord-005646-xhx9pzhj 654 37 minor minor JJ cord-005646-xhx9pzhj 654 38 hemodynamie hemodynamie NN cord-005646-xhx9pzhj 654 39 complications complication NNS cord-005646-xhx9pzhj 654 40 . . . cord-005646-xhx9pzhj 655 1 The the DT cord-005646-xhx9pzhj 655 2 value value NN cord-005646-xhx9pzhj 655 3 of of IN cord-005646-xhx9pzhj 655 4 pHi phi NN cord-005646-xhx9pzhj 655 5 lower low JJR cord-005646-xhx9pzhj 655 6 than than IN cord-005646-xhx9pzhj 655 7 730 730 CD cord-005646-xhx9pzhj 655 8 presented present VBD cord-005646-xhx9pzhj 655 9 a a DT cord-005646-xhx9pzhj 655 10 90 90 CD cord-005646-xhx9pzhj 655 11 % % NN cord-005646-xhx9pzhj 655 12 of of IN cord-005646-xhx9pzhj 655 13 sensibility sensibility NN cord-005646-xhx9pzhj 655 14 and and CC cord-005646-xhx9pzhj 655 15 98 98 CD cord-005646-xhx9pzhj 655 16 % % NN cord-005646-xhx9pzhj 655 17 of of IN cord-005646-xhx9pzhj 655 18 specificity specificity NN cord-005646-xhx9pzhj 655 19 with with IN cord-005646-xhx9pzhj 655 20 regard regard NN cord-005646-xhx9pzhj 655 21 to to IN cord-005646-xhx9pzhj 655 22 hemodymanic hemodymanic JJ cord-005646-xhx9pzhj 655 23 complications complication NNS cord-005646-xhx9pzhj 655 24 . . . cord-005646-xhx9pzhj 656 1 There there EX cord-005646-xhx9pzhj 656 2 was be VBD cord-005646-xhx9pzhj 656 3 no no DT cord-005646-xhx9pzhj 656 4 relationship relationship NN cord-005646-xhx9pzhj 656 5 between between IN cord-005646-xhx9pzhj 656 6 pHi pHi NNP cord-005646-xhx9pzhj 656 7 < < XX cord-005646-xhx9pzhj 656 8 7.30 7.30 CD cord-005646-xhx9pzhj 656 9 and and CC cord-005646-xhx9pzhj 656 10 PRIMS PRIMS NNP cord-005646-xhx9pzhj 656 11 score score VBP cord-005646-xhx9pzhj 656 12 and and CC cord-005646-xhx9pzhj 656 13 stay stay VB cord-005646-xhx9pzhj 656 14 in in IN cord-005646-xhx9pzhj 656 15 PICU PICU NNP cord-005646-xhx9pzhj 656 16 . . . cord-005646-xhx9pzhj 657 1 Patients patient NNS cord-005646-xhx9pzhj 657 2 with with IN cord-005646-xhx9pzhj 657 3 pHi pHi NNPS cord-005646-xhx9pzhj 657 4 < < XX cord-005646-xhx9pzhj 657 5 7.20 7.20 CD cord-005646-xhx9pzhj 657 6 presented present VBD cord-005646-xhx9pzhj 657 7 a a DT cord-005646-xhx9pzhj 657 8 PRIMS PRIMS NNP cord-005646-xhx9pzhj 657 9 higher high JJR cord-005646-xhx9pzhj 657 10 than than IN cord-005646-xhx9pzhj 657 11 the the DT cord-005646-xhx9pzhj 657 12 rest rest NN cord-005646-xhx9pzhj 657 13 of of IN cord-005646-xhx9pzhj 657 14 patients patient NNS cord-005646-xhx9pzhj 657 15 ( ( -LRB- cord-005646-xhx9pzhj 657 16 p p NN cord-005646-xhx9pzhj 657 17 < < XX cord-005646-xhx9pzhj 657 18 0.05 0.05 CD cord-005646-xhx9pzhj 657 19 ) ) -RRB- cord-005646-xhx9pzhj 657 20 . . . cord-005646-xhx9pzhj 658 1 CONCLUSIONS conclusion NNS cord-005646-xhx9pzhj 658 2 : : : cord-005646-xhx9pzhj 659 1 The the DT cord-005646-xhx9pzhj 659 2 pHi phi JJ cord-005646-xhx9pzhj 659 3 value value NN cord-005646-xhx9pzhj 659 4 may may MD cord-005646-xhx9pzhj 659 5 be be VB cord-005646-xhx9pzhj 659 6 an an DT cord-005646-xhx9pzhj 659 7 early early JJ cord-005646-xhx9pzhj 659 8 sign sign NN cord-005646-xhx9pzhj 659 9 of of IN cord-005646-xhx9pzhj 659 10 presence presence NN cord-005646-xhx9pzhj 659 11 of of IN cord-005646-xhx9pzhj 659 12 hem0dyaaimc hem0dyaaimc NNP cord-005646-xhx9pzhj 659 13 complications complication NNS cord-005646-xhx9pzhj 659 14 in in IN cord-005646-xhx9pzhj 659 15 the the DT cord-005646-xhx9pzhj 659 16 critically critically RB cord-005646-xhx9pzhj 659 17 ill ill JJ cord-005646-xhx9pzhj 659 18 child child NN cord-005646-xhx9pzhj 659 19 . . . cord-005646-xhx9pzhj 660 1 We -PRON- PRP cord-005646-xhx9pzhj 660 2 tested test VBD cord-005646-xhx9pzhj 660 3 the the DT cord-005646-xhx9pzhj 660 4 hypothesis hypothesis NN cord-005646-xhx9pzhj 660 5 that that IN cord-005646-xhx9pzhj 660 6 Gastric gastric JJ cord-005646-xhx9pzhj 660 7 intramural intramural JJ cord-005646-xhx9pzhj 660 8 pH ph NN cord-005646-xhx9pzhj 660 9 ( ( -LRB- cord-005646-xhx9pzhj 660 10 pHi pHi NNP cord-005646-xhx9pzhj 660 11 ) ) -RRB- cord-005646-xhx9pzhj 660 12 can can MD cord-005646-xhx9pzhj 660 13 be be VB cord-005646-xhx9pzhj 660 14 used use VBN cord-005646-xhx9pzhj 660 15 as as IN cord-005646-xhx9pzhj 660 16 an an DT cord-005646-xhx9pzhj 660 17 early early JJ cord-005646-xhx9pzhj 660 18 sign sign NN cord-005646-xhx9pzhj 660 19 of of IN cord-005646-xhx9pzhj 660 20 failure failure NN cord-005646-xhx9pzhj 660 21 m m NNP cord-005646-xhx9pzhj 660 22 weaning wean VBG cord-005646-xhx9pzhj 660 23 pediatric pediatric JJ cord-005646-xhx9pzhj 660 24 patients patient NNS cord-005646-xhx9pzhj 660 25 because because IN cord-005646-xhx9pzhj 660 26 the the DT cord-005646-xhx9pzhj 660 27 blood blood NN cord-005646-xhx9pzhj 660 28 flow flow NN cord-005646-xhx9pzhj 660 29 from from IN cord-005646-xhx9pzhj 660 30 nonvital nonvital JJ cord-005646-xhx9pzhj 660 31 areas area NNS cord-005646-xhx9pzhj 660 32 is be VBZ cord-005646-xhx9pzhj 660 33 diverted divert VBN cord-005646-xhx9pzhj 660 34 to to TO cord-005646-xhx9pzhj 660 35 meet meet VB cord-005646-xhx9pzhj 660 36 the the DT cord-005646-xhx9pzhj 660 37 increased increase VBN cord-005646-xhx9pzhj 660 38 demands demand NNS cord-005646-xhx9pzhj 660 39 of of IN cord-005646-xhx9pzhj 660 40 respiratory respiratory JJ cord-005646-xhx9pzhj 660 41 muscles muscle NNS cord-005646-xhx9pzhj 660 42 . . . cord-005646-xhx9pzhj 661 1 METHODS method NNS cord-005646-xhx9pzhj 661 2 : : : cord-005646-xhx9pzhj 661 3 24 24 CD cord-005646-xhx9pzhj 661 4 children child NNS cord-005646-xhx9pzhj 661 5 ( ( -LRB- cord-005646-xhx9pzhj 661 6 mean mean VB cord-005646-xhx9pzhj 661 7 age age NN cord-005646-xhx9pzhj 661 8 ( ( -LRB- cord-005646-xhx9pzhj 661 9 4.2_+0.3 4.2_+0.3 CD cord-005646-xhx9pzhj 661 10 ) ) -RRB- cord-005646-xhx9pzhj 661 11 years year NNS cord-005646-xhx9pzhj 661 12 + + CC cord-005646-xhx9pzhj 661 13 SD sd NN cord-005646-xhx9pzhj 661 14 ) ) -RRB- cord-005646-xhx9pzhj 661 15 who who WP cord-005646-xhx9pzhj 661 16 were be VBD cord-005646-xhx9pzhj 661 17 thought think VBN cord-005646-xhx9pzhj 661 18 by by IN cord-005646-xhx9pzhj 661 19 their -PRON- PRP$ cord-005646-xhx9pzhj 661 20 physicians physician NNS cord-005646-xhx9pzhj 661 21 to to TO cord-005646-xhx9pzhj 661 22 be be VB cord-005646-xhx9pzhj 661 23 weanable weanable JJ cord-005646-xhx9pzhj 661 24 from from IN cord-005646-xhx9pzhj 661 25 Mechanical mechanical JJ cord-005646-xhx9pzhj 661 26 ventilation ventilation NN cord-005646-xhx9pzhj 661 27 ( ( -LRB- cord-005646-xhx9pzhj 661 28 MV MV NNP cord-005646-xhx9pzhj 661 29 . . . cord-005646-xhx9pzhj 661 30 ) ) -RRB- cord-005646-xhx9pzhj 661 31 . . . cord-005646-xhx9pzhj 662 1 These these DT cord-005646-xhx9pzhj 662 2 patients patient NNS cord-005646-xhx9pzhj 662 3 were be VBD cord-005646-xhx9pzhj 662 4 ventilated ventilate VBN cord-005646-xhx9pzhj 662 5 on on IN cord-005646-xhx9pzhj 662 6 Serve Serve NNP cord-005646-xhx9pzhj 662 7 900C 900C NNP cord-005646-xhx9pzhj 662 8 ventilators ventilator NNS cord-005646-xhx9pzhj 662 9 , , , cord-005646-xhx9pzhj 662 10 receiving receive VBG cord-005646-xhx9pzhj 662 11 ranitidine ranitidine NN cord-005646-xhx9pzhj 662 12 , , , cord-005646-xhx9pzhj 662 13 and and CC cord-005646-xhx9pzhj 662 14 had have VBD cord-005646-xhx9pzhj 662 15 intestinal intestinal JJ cord-005646-xhx9pzhj 662 16 tonometer tonometer NN cord-005646-xhx9pzhj 662 17 ( ( -LRB- cord-005646-xhx9pzhj 662 18 tonometrics tonometrics NNP cord-005646-xhx9pzhj 662 19 , , , cord-005646-xhx9pzhj 662 20 inc inc NNP cord-005646-xhx9pzhj 662 21 . . NNP cord-005646-xhx9pzhj 662 22 ) ) -RRB- cord-005646-xhx9pzhj 663 1 60 60 CD cord-005646-xhx9pzhj 663 2 minutes minute NNS cord-005646-xhx9pzhj 663 3 before before IN cord-005646-xhx9pzhj 663 4 obtaining obtain VBG cord-005646-xhx9pzhj 663 5 a a DT cord-005646-xhx9pzhj 663 6 sample sample NN cord-005646-xhx9pzhj 663 7 .. .. . cord-005646-xhx9pzhj 664 1 All all DT cord-005646-xhx9pzhj 664 2 children child NNS cord-005646-xhx9pzhj 664 3 were be VBD cord-005646-xhx9pzhj 664 4 placed place VBN cord-005646-xhx9pzhj 664 5 on on IN cord-005646-xhx9pzhj 664 6 pressure pressure NN cord-005646-xhx9pzhj 664 7 support support NN cord-005646-xhx9pzhj 664 8 ( ( -LRB- cord-005646-xhx9pzhj 664 9 PS PS NNP cord-005646-xhx9pzhj 664 10 ) ) -RRB- cord-005646-xhx9pzhj 664 11 at at IN cord-005646-xhx9pzhj 664 12 levels level NNS cord-005646-xhx9pzhj 664 13 judged judge VBN cord-005646-xhx9pzhj 664 14 to to TO cord-005646-xhx9pzhj 664 15 overcome overcome VB cord-005646-xhx9pzhj 664 16 the the DT cord-005646-xhx9pzhj 664 17 resistance resistance NN cord-005646-xhx9pzhj 664 18 of of IN cord-005646-xhx9pzhj 664 19 the the DT cord-005646-xhx9pzhj 664 20 endotracheal endotracheal NN cord-005646-xhx9pzhj 664 21 tube tube NN cord-005646-xhx9pzhj 664 22 and and CC cord-005646-xhx9pzhj 664 23 ventilatory ventilatory NN cord-005646-xhx9pzhj 664 24 circuit circuit NN cord-005646-xhx9pzhj 664 25 ( ( -LRB- cord-005646-xhx9pzhj 664 26 2 2 CD cord-005646-xhx9pzhj 664 27 em -PRON- PRP cord-005646-xhx9pzhj 664 28 H.,O h.,o CD cord-005646-xhx9pzhj 664 29 ) ) -RRB- cord-005646-xhx9pzhj 664 30 . . . cord-005646-xhx9pzhj 665 1 A a DT cord-005646-xhx9pzhj 665 2 sample sample NN cord-005646-xhx9pzhj 665 3 of of IN cord-005646-xhx9pzhj 665 4 arterial arterial JJ cord-005646-xhx9pzhj 665 5 blood blood NN cord-005646-xhx9pzhj 665 6 and and CC cord-005646-xhx9pzhj 665 7 a a DT cord-005646-xhx9pzhj 665 8 sample sample NN cord-005646-xhx9pzhj 665 9 oftonometer oftonometer NN cord-005646-xhx9pzhj 665 10 were be VBD cord-005646-xhx9pzhj 665 11 obtained obtain VBN cord-005646-xhx9pzhj 665 12 during during IN cord-005646-xhx9pzhj 665 13 VM VM NNP cord-005646-xhx9pzhj 665 14 and and CC cord-005646-xhx9pzhj 665 15 weaning weaning NN cord-005646-xhx9pzhj 665 16 ( ( -LRB- cord-005646-xhx9pzhj 665 17 PS PS NNP cord-005646-xhx9pzhj 665 18 ) ) -RRB- cord-005646-xhx9pzhj 665 19 . . . cord-005646-xhx9pzhj 666 1 pHi phi JJ cord-005646-xhx9pzhj 666 2 , , , cord-005646-xhx9pzhj 666 3 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 666 4 and and CC cord-005646-xhx9pzhj 666 5 respiratory respiratory JJ cord-005646-xhx9pzhj 666 6 data datum NNS cord-005646-xhx9pzhj 666 7 were be VBD cord-005646-xhx9pzhj 666 8 recorded record VBN cord-005646-xhx9pzhj 666 9 during during IN cord-005646-xhx9pzhj 666 10 VM VM NNP cord-005646-xhx9pzhj 666 11 and and CC cord-005646-xhx9pzhj 666 12 weaning wean VBG cord-005646-xhx9pzhj 666 13 We -PRON- PRP cord-005646-xhx9pzhj 666 14 did do VBD cord-005646-xhx9pzhj 666 15 not not RB cord-005646-xhx9pzhj 666 16 interfere interfere VB cord-005646-xhx9pzhj 666 17 with with IN cord-005646-xhx9pzhj 666 18 the the DT cord-005646-xhx9pzhj 666 19 primary primary JJ cord-005646-xhx9pzhj 666 20 caretaker caretaker NN cord-005646-xhx9pzhj 666 21 's 's POS cord-005646-xhx9pzhj 666 22 decisions decision NNS cord-005646-xhx9pzhj 666 23 regarding regard VBG cord-005646-xhx9pzhj 666 24 extubation extubation NN cord-005646-xhx9pzhj 666 25 . . . cord-005646-xhx9pzhj 667 1 Patients patient NNS cord-005646-xhx9pzhj 667 2 were be VBD cord-005646-xhx9pzhj 667 3 considered consider VBN cord-005646-xhx9pzhj 667 4 to to TO cord-005646-xhx9pzhj 667 5 be be VB cord-005646-xhx9pzhj 667 6 successfully successfully RB cord-005646-xhx9pzhj 667 7 weaned wean VBN cord-005646-xhx9pzhj 667 8 if if IN cord-005646-xhx9pzhj 667 9 they -PRON- PRP cord-005646-xhx9pzhj 667 10 were be VBD cord-005646-xhx9pzhj 667 11 able able JJ cord-005646-xhx9pzhj 667 12 to to TO cord-005646-xhx9pzhj 667 13 sustain sustain VB cord-005646-xhx9pzhj 667 14 spontaneous spontaneous JJ cord-005646-xhx9pzhj 667 15 ventilation ventilation NN cord-005646-xhx9pzhj 667 16 for for IN cord-005646-xhx9pzhj 667 17 more more JJR cord-005646-xhx9pzhj 667 18 than than IN cord-005646-xhx9pzhj 667 19 24 24 CD cord-005646-xhx9pzhj 667 20 hours hour NNS cord-005646-xhx9pzhj 667 21 after after IN cord-005646-xhx9pzhj 667 22 extubation extubation NN cord-005646-xhx9pzhj 667 23 . . . cord-005646-xhx9pzhj 668 1 Paired paired JJ cord-005646-xhx9pzhj 668 2 t t NN cord-005646-xhx9pzhj 668 3 - - HYPH cord-005646-xhx9pzhj 668 4 test test NN cord-005646-xhx9pzhj 668 5 were be VBD cord-005646-xhx9pzhj 668 6 used use VBN cord-005646-xhx9pzhj 668 7 to to TO cord-005646-xhx9pzhj 668 8 compare compare VB cord-005646-xhx9pzhj 668 9 the the DT cord-005646-xhx9pzhj 668 10 values value NNS cord-005646-xhx9pzhj 668 11 obtained obtain VBN cord-005646-xhx9pzhj 668 12 during during IN cord-005646-xhx9pzhj 668 13 mechanical mechanical JJ cord-005646-xhx9pzhj 668 14 ventilation ventilation NN cord-005646-xhx9pzhj 668 15 with with IN cord-005646-xhx9pzhj 668 16 those those DT cord-005646-xhx9pzhj 668 17 obtained obtain VBN cord-005646-xhx9pzhj 668 18 during during IN cord-005646-xhx9pzhj 668 19 weaning wean VBG cord-005646-xhx9pzhj 668 20 trials trial NNS cord-005646-xhx9pzhj 668 21 . . . cord-005646-xhx9pzhj 669 1 Unpaired Unpaired NNP cord-005646-xhx9pzhj 669 2 ttest ttest NNP cord-005646-xhx9pzhj 669 3 were be VBD cord-005646-xhx9pzhj 669 4 used use VBN cord-005646-xhx9pzhj 669 5 to to TO cord-005646-xhx9pzhj 669 6 compare compare VB cord-005646-xhx9pzhj 669 7 values value NNS cord-005646-xhx9pzhj 669 8 from from IN cord-005646-xhx9pzhj 669 9 the the DT cord-005646-xhx9pzhj 669 10 group group NN cord-005646-xhx9pzhj 669 11 that that WDT cord-005646-xhx9pzhj 669 12 was be VBD cord-005646-xhx9pzhj 669 13 successfully successfully RB cord-005646-xhx9pzhj 669 14 weaned wean VBN cord-005646-xhx9pzhj 669 15 ( ( -LRB- cord-005646-xhx9pzhj 669 16 A a NN cord-005646-xhx9pzhj 669 17 = = SYM cord-005646-xhx9pzhj 669 18 I5 I5 NNP cord-005646-xhx9pzhj 669 19 ) ) -RRB- cord-005646-xhx9pzhj 669 20 with with IN cord-005646-xhx9pzhj 669 21 those those DT cord-005646-xhx9pzhj 669 22 from from IN cord-005646-xhx9pzhj 669 23 the the DT cord-005646-xhx9pzhj 669 24 group group NN cord-005646-xhx9pzhj 669 25 that that WDT cord-005646-xhx9pzhj 669 26 were be VBD cord-005646-xhx9pzhj 669 27 not not RB cord-005646-xhx9pzhj 669 28 ( ( -LRB- cord-005646-xhx9pzhj 669 29 B=9 B=9 NNP cord-005646-xhx9pzhj 669 30 ) ) -RRB- cord-005646-xhx9pzhj 669 31 . . . cord-005646-xhx9pzhj 670 1 RESULTS result NNS cord-005646-xhx9pzhj 670 2 : : : cord-005646-xhx9pzhj 671 1 We -PRON- PRP cord-005646-xhx9pzhj 671 2 did do VBD cord-005646-xhx9pzhj 671 3 not not RB cord-005646-xhx9pzhj 671 4 find find VB cord-005646-xhx9pzhj 671 5 statistical statistical JJ cord-005646-xhx9pzhj 671 6 differences difference NNS cord-005646-xhx9pzhj 671 7 in in IN cord-005646-xhx9pzhj 671 8 any any DT cord-005646-xhx9pzhj 671 9 of of IN cord-005646-xhx9pzhj 671 10 those those DT cord-005646-xhx9pzhj 671 11 variables variable NNS cord-005646-xhx9pzhj 671 12 mesured mesure VBN cord-005646-xhx9pzhj 671 13 during during IN cord-005646-xhx9pzhj 671 14 MV MV NNP cord-005646-xhx9pzhj 671 15 for for IN cord-005646-xhx9pzhj 671 16 patients patient NNS cord-005646-xhx9pzhj 671 17 who who WP cord-005646-xhx9pzhj 671 18 were be VBD cord-005646-xhx9pzhj 671 19 successfully successfully RB cord-005646-xhx9pzhj 671 20 weaned(group weaned(group WDT cord-005646-xhx9pzhj 671 21 A a NN cord-005646-xhx9pzhj 671 22 ) ) -RRB- cord-005646-xhx9pzhj 671 23 and and CC cord-005646-xhx9pzhj 671 24 those those DT cord-005646-xhx9pzhj 671 25 who who WP cord-005646-xhx9pzhj 671 26 were be VBD cord-005646-xhx9pzhj 671 27 not not RB cord-005646-xhx9pzhj 671 28 ( ( -LRB- cord-005646-xhx9pzhj 671 29 group group NN cord-005646-xhx9pzhj 671 30 B B NNP cord-005646-xhx9pzhj 671 31 ) ) -RRB- cord-005646-xhx9pzhj 671 32 . . . cord-005646-xhx9pzhj 672 1 Gastric gastric JJ cord-005646-xhx9pzhj 672 2 phi phi NN cord-005646-xhx9pzhj 672 3 was be VBD cord-005646-xhx9pzhj 672 4 in in IN cord-005646-xhx9pzhj 672 5 group group NN cord-005646-xhx9pzhj 672 6 A a NN cord-005646-xhx9pzhj 672 7 : : : cord-005646-xhx9pzhj 672 8 7.35 7.35 CD cord-005646-xhx9pzhj 672 9 + + SYM cord-005646-xhx9pzhj 672 10 0.03 0.03 CD cord-005646-xhx9pzhj 672 11 ( ( -LRB- cord-005646-xhx9pzhj 672 12 VM VM NNP cord-005646-xhx9pzhj 672 13 ) ) -RRB- cord-005646-xhx9pzhj 672 14 and and CC cord-005646-xhx9pzhj 672 15 739 739 CD cord-005646-xhx9pzhj 672 16 + + CD cord-005646-xhx9pzhj 672 17 0.02 0.02 CD cord-005646-xhx9pzhj 672 18 ( ( -LRB- cord-005646-xhx9pzhj 672 19 weaning wean VBG cord-005646-xhx9pzhj 672 20 ) ) -RRB- cord-005646-xhx9pzhj 672 21 ; ; : cord-005646-xhx9pzhj 672 22 in in IN cord-005646-xhx9pzhj 672 23 group group NN cord-005646-xhx9pzhj 672 24 B B NNP cord-005646-xhx9pzhj 672 25 : : : cord-005646-xhx9pzhj 672 26 7.40 7.40 CD cord-005646-xhx9pzhj 672 27 _ _ NN cord-005646-xhx9pzhj 672 28 + + SYM cord-005646-xhx9pzhj 672 29 0.04 0.04 CD cord-005646-xhx9pzhj 672 30 ( ( -LRB- cord-005646-xhx9pzhj 672 31 VM VM NNP cord-005646-xhx9pzhj 672 32 ) ) -RRB- cord-005646-xhx9pzhj 672 33 and and CC cord-005646-xhx9pzhj 672 34 7.4 7.4 CD cord-005646-xhx9pzhj 672 35 t t NN cord-005646-xhx9pzhj 672 36 _ _ NN cord-005646-xhx9pzhj 672 37 + + CC cord-005646-xhx9pzhj 672 38 0.02 0.02 CD cord-005646-xhx9pzhj 672 39 ( ( -LRB- cord-005646-xhx9pzhj 672 40 weaning weaning NN cord-005646-xhx9pzhj 672 41 ) ) -RRB- cord-005646-xhx9pzhj 672 42 . . . cord-005646-xhx9pzhj 673 1 DISCUSSION discussion NN cord-005646-xhx9pzhj 673 2 : : : cord-005646-xhx9pzhj 674 1 Although although IN cord-005646-xhx9pzhj 674 2 we -PRON- PRP cord-005646-xhx9pzhj 674 3 did do VBD cord-005646-xhx9pzhj 674 4 not not RB cord-005646-xhx9pzhj 674 5 find find VB cord-005646-xhx9pzhj 674 6 differences difference NNS cord-005646-xhx9pzhj 674 7 in in IN cord-005646-xhx9pzhj 674 8 gastric gastric JJ cord-005646-xhx9pzhj 674 9 pHi pHi NNS cord-005646-xhx9pzhj 674 10 during during IN cord-005646-xhx9pzhj 674 11 VM VM NNP cord-005646-xhx9pzhj 674 12 , , , cord-005646-xhx9pzhj 674 13 the the DT cord-005646-xhx9pzhj 674 14 group group NN cord-005646-xhx9pzhj 674 15 A A NNP cord-005646-xhx9pzhj 674 16 had have VBD cord-005646-xhx9pzhj 674 17 a a DT cord-005646-xhx9pzhj 674 18 lower low JJR cord-005646-xhx9pzhj 674 19 value value NN cord-005646-xhx9pzhj 674 20 than than IN cord-005646-xhx9pzhj 674 21 group group NN cord-005646-xhx9pzhj 674 22 B b NN cord-005646-xhx9pzhj 674 23 because because IN cord-005646-xhx9pzhj 674 24 of of IN cord-005646-xhx9pzhj 674 25 the the DT cord-005646-xhx9pzhj 674 26 number number NN cord-005646-xhx9pzhj 674 27 of of IN cord-005646-xhx9pzhj 674 28 cardiac cardiac JJ cord-005646-xhx9pzhj 674 29 patients patient NNS cord-005646-xhx9pzhj 674 30 ( ( -LRB- cord-005646-xhx9pzhj 674 31 70 70 CD cord-005646-xhx9pzhj 674 32 % % NN cord-005646-xhx9pzhj 674 33 ) ) -RRB- cord-005646-xhx9pzhj 674 34 and and CC cord-005646-xhx9pzhj 674 35 transfusion transfusion NN cord-005646-xhx9pzhj 674 36 therapy therapy NN cord-005646-xhx9pzhj 674 37 , , , cord-005646-xhx9pzhj 674 38 in in IN cord-005646-xhx9pzhj 674 39 fins fin NNS cord-005646-xhx9pzhj 674 40 group group NN cord-005646-xhx9pzhj 674 41 . . . cord-005646-xhx9pzhj 675 1 In in IN cord-005646-xhx9pzhj 675 2 group group NN cord-005646-xhx9pzhj 675 3 B b NN cord-005646-xhx9pzhj 675 4 75 75 CD cord-005646-xhx9pzhj 675 5 % % NN cord-005646-xhx9pzhj 675 6 of of IN cord-005646-xhx9pzhj 675 7 patients patient NNS cord-005646-xhx9pzhj 675 8 showed show VBD cord-005646-xhx9pzhj 675 9 a a DT cord-005646-xhx9pzhj 675 10 problem problem NN cord-005646-xhx9pzhj 675 11 in in IN cord-005646-xhx9pzhj 675 12 upper upper JJ cord-005646-xhx9pzhj 675 13 airway airway NN cord-005646-xhx9pzhj 675 14 ( ( -LRB- cord-005646-xhx9pzhj 675 15 subglottic subglottic JJ cord-005646-xhx9pzhj 675 16 edema edema NN cord-005646-xhx9pzhj 675 17 , , , cord-005646-xhx9pzhj 675 18 and and CC cord-005646-xhx9pzhj 675 19 enlarged enlarged JJ cord-005646-xhx9pzhj 675 20 tonsils tonsil NNS cord-005646-xhx9pzhj 675 21 ) ) -RRB- cord-005646-xhx9pzhj 675 22 . . . cord-005646-xhx9pzhj 676 1 We -PRON- PRP cord-005646-xhx9pzhj 676 2 found find VBD cord-005646-xhx9pzhj 676 3 it -PRON- PRP cord-005646-xhx9pzhj 676 4 after after IN cord-005646-xhx9pzhj 676 5 extubation extubation NN cord-005646-xhx9pzhj 676 6 . . . cord-005646-xhx9pzhj 677 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 677 2 : : : cord-005646-xhx9pzhj 677 3 1 1 LS cord-005646-xhx9pzhj 677 4 ) ) -RRB- cord-005646-xhx9pzhj 678 1 Gastric gastric JJ cord-005646-xhx9pzhj 678 2 phi phi NN cord-005646-xhx9pzhj 678 3 is be VBZ cord-005646-xhx9pzhj 678 4 a a DT cord-005646-xhx9pzhj 678 5 good good JJ cord-005646-xhx9pzhj 678 6 predictor predictor NN cord-005646-xhx9pzhj 678 7 of of IN cord-005646-xhx9pzhj 678 8 risk risk NN cord-005646-xhx9pzhj 678 9 in in IN cord-005646-xhx9pzhj 678 10 critically critically RB cord-005646-xhx9pzhj 678 11 ill ill JJ cord-005646-xhx9pzhj 678 12 patients patient NNS cord-005646-xhx9pzhj 678 13 but but CC cord-005646-xhx9pzhj 678 14 maybe maybe RB cord-005646-xhx9pzhj 678 15 because because IN cord-005646-xhx9pzhj 678 16 of of IN cord-005646-xhx9pzhj 678 17 the the DT cord-005646-xhx9pzhj 678 18 small small JJ cord-005646-xhx9pzhj 678 19 size size NN cord-005646-xhx9pzhj 678 20 of of IN cord-005646-xhx9pzhj 678 21 the the DT cord-005646-xhx9pzhj 678 22 sample sample NN cord-005646-xhx9pzhj 678 23 , , , cord-005646-xhx9pzhj 678 24 in in IN cord-005646-xhx9pzhj 678 25 our -PRON- PRP$ cord-005646-xhx9pzhj 678 26 study study NN cord-005646-xhx9pzhj 678 27 is be VBZ cord-005646-xhx9pzhj 678 28 not not RB cord-005646-xhx9pzhj 678 29 of of IN cord-005646-xhx9pzhj 678 30 practical practical JJ cord-005646-xhx9pzhj 678 31 value value NN cord-005646-xhx9pzhj 678 32 as as IN cord-005646-xhx9pzhj 678 33 a a DT cord-005646-xhx9pzhj 678 34 predictor predictor NN cord-005646-xhx9pzhj 678 35 of of IN cord-005646-xhx9pzhj 678 36 failure failure NN cord-005646-xhx9pzhj 678 37 in in IN cord-005646-xhx9pzhj 678 38 weaning wean VBG cord-005646-xhx9pzhj 678 39 pediatric pediatric JJ cord-005646-xhx9pzhj 678 40 patients patient NNS cord-005646-xhx9pzhj 678 41 from from IN cord-005646-xhx9pzhj 678 42 VM VM NNP cord-005646-xhx9pzhj 678 43 . . . cord-005646-xhx9pzhj 679 1 2 2 LS cord-005646-xhx9pzhj 679 2 ) ) -RRB- cord-005646-xhx9pzhj 680 1 This this DT cord-005646-xhx9pzhj 680 2 test test NN cord-005646-xhx9pzhj 680 3 is be VBZ cord-005646-xhx9pzhj 680 4 not not RB cord-005646-xhx9pzhj 680 5 a a DT cord-005646-xhx9pzhj 680 6 predictor predictor NN cord-005646-xhx9pzhj 680 7 of of IN cord-005646-xhx9pzhj 680 8 problems problem NNS cord-005646-xhx9pzhj 680 9 in in IN cord-005646-xhx9pzhj 680 10 upper upper JJ cord-005646-xhx9pzhj 680 11 airway~ airway~ RB cord-005646-xhx9pzhj 680 12 important important JJ cord-005646-xhx9pzhj 680 13 etiology etiology NN cord-005646-xhx9pzhj 680 14 of of IN cord-005646-xhx9pzhj 680 15 failure failure NN cord-005646-xhx9pzhj 680 16 weaning wean VBG cord-005646-xhx9pzhj 680 17 in in IN cord-005646-xhx9pzhj 680 18 children child NNS cord-005646-xhx9pzhj 680 19 . . . cord-005646-xhx9pzhj 681 1 Objectives objective NNS cord-005646-xhx9pzhj 681 2 : : : cord-005646-xhx9pzhj 681 3 I -PRON- PRP cord-005646-xhx9pzhj 681 4 - - : cord-005646-xhx9pzhj 681 5 To to TO cord-005646-xhx9pzhj 681 6 determine determine VB cord-005646-xhx9pzhj 681 7 the the DT cord-005646-xhx9pzhj 681 8 prognostic prognostic JJ cord-005646-xhx9pzhj 681 9 value value NN cord-005646-xhx9pzhj 681 10 of of IN cord-005646-xhx9pzhj 681 11 the the DT cord-005646-xhx9pzhj 681 12 gastric gastric JJ cord-005646-xhx9pzhj 681 13 intramueesal intramueesal NN cord-005646-xhx9pzhj 681 14 pHi pHi NNS cord-005646-xhx9pzhj 681 15 in in IN cord-005646-xhx9pzhj 681 16 mortality mortality NN cord-005646-xhx9pzhj 681 17 and and CC cord-005646-xhx9pzhj 681 18 multiple multiple JJ cord-005646-xhx9pzhj 681 19 organ organ NN cord-005646-xhx9pzhj 681 20 dysfunction dysfunction NN cord-005646-xhx9pzhj 681 21 ( ( -LRB- cord-005646-xhx9pzhj 681 22 SDMO SDMO NNP cord-005646-xhx9pzhj 681 23 ) ) -RRB- cord-005646-xhx9pzhj 681 24 in in IN cord-005646-xhx9pzhj 681 25 critically critically RB cord-005646-xhx9pzhj 681 26 ill ill JJ cord-005646-xhx9pzhj 681 27 children child NNS cord-005646-xhx9pzhj 681 28 . . . cord-005646-xhx9pzhj 682 1 2-To 2-to CD cord-005646-xhx9pzhj 682 2 compare compare VBP cord-005646-xhx9pzhj 682 3 this this DT cord-005646-xhx9pzhj 682 4 value value NN cord-005646-xhx9pzhj 682 5 , , , cord-005646-xhx9pzhj 682 6 with with IN cord-005646-xhx9pzhj 682 7 the the DT cord-005646-xhx9pzhj 682 8 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 682 9 Risk Risk NNP cord-005646-xhx9pzhj 682 10 Index Index NNP cord-005646-xhx9pzhj 682 11 Mortality Mortality NNP cord-005646-xhx9pzhj 682 12 Score Score NNP cord-005646-xhx9pzhj 682 13 ( ( -LRB- cord-005646-xhx9pzhj 682 14 PRIMS PRIMS NNP cord-005646-xhx9pzhj 682 15 ) ) -RRB- cord-005646-xhx9pzhj 682 16 . . . cord-005646-xhx9pzhj 683 1 Methods method NNS cord-005646-xhx9pzhj 683 2 : : : cord-005646-xhx9pzhj 684 1 Aprospective aprospective JJ cord-005646-xhx9pzhj 684 2 study study NN cord-005646-xhx9pzhj 684 3 was be VBD cord-005646-xhx9pzhj 684 4 performed perform VBN cord-005646-xhx9pzhj 684 5 with with IN cord-005646-xhx9pzhj 684 6 51 51 CD cord-005646-xhx9pzhj 684 7 critically critically RB cord-005646-xhx9pzhj 684 8 illcbildren illcbildren NNP cord-005646-xhx9pzhj 684 9 , , , cord-005646-xhx9pzhj 684 10 aged age VBN cord-005646-xhx9pzhj 684 11 from from IN cord-005646-xhx9pzhj 684 12 1 1 CD cord-005646-xhx9pzhj 684 13 mouth mouth NN cord-005646-xhx9pzhj 684 14 to to IN cord-005646-xhx9pzhj 684 15 16 16 CD cord-005646-xhx9pzhj 684 16 years year NNS cord-005646-xhx9pzhj 684 17 . . . cord-005646-xhx9pzhj 685 1 The the DT cord-005646-xhx9pzhj 685 2 athnittiug athnittiug NNP cord-005646-xhx9pzhj 685 3 diagnosis diagnosis NN cord-005646-xhx9pzhj 685 4 was be VBD cord-005646-xhx9pzhj 685 5 : : : cord-005646-xhx9pzhj 685 6 26 26 CD cord-005646-xhx9pzhj 685 7 post post NN cord-005646-xhx9pzhj 685 8 - - NN cord-005646-xhx9pzhj 685 9 surgery surgery NN cord-005646-xhx9pzhj 685 10 ( ( -LRB- cord-005646-xhx9pzhj 685 11 13 13 CD cord-005646-xhx9pzhj 685 12 neurosurgery neurosurgery NN cord-005646-xhx9pzhj 685 13 , , , cord-005646-xhx9pzhj 685 14 9 9 CD cord-005646-xhx9pzhj 685 15 spinal spinal JJ cord-005646-xhx9pzhj 685 16 fusion fusion NN cord-005646-xhx9pzhj 685 17 and and CC cord-005646-xhx9pzhj 685 18 4 4 CD cord-005646-xhx9pzhj 685 19 thoracic thoracic JJ cord-005646-xhx9pzhj 685 20 or or CC cord-005646-xhx9pzhj 685 21 abdominal abdominal JJ cord-005646-xhx9pzhj 685 22 surgery surgery NN cord-005646-xhx9pzhj 685 23 ) ) -RRB- cord-005646-xhx9pzhj 685 24 , , , cord-005646-xhx9pzhj 685 25 7 7 CD cord-005646-xhx9pzhj 685 26 sepsis sepsis NN cord-005646-xhx9pzhj 685 27 , , , cord-005646-xhx9pzhj 685 28 6 6 CD cord-005646-xhx9pzhj 685 29 polytraumatism polytraumatism NN cord-005646-xhx9pzhj 685 30 , , , cord-005646-xhx9pzhj 685 31 5 5 CD cord-005646-xhx9pzhj 685 32 adult adult NN cord-005646-xhx9pzhj 685 33 respiratory respiratory JJ cord-005646-xhx9pzhj 685 34 distress distress NN cord-005646-xhx9pzhj 685 35 syndrome syndrome NN cord-005646-xhx9pzhj 685 36 and and CC cord-005646-xhx9pzhj 685 37 8 8 CD cord-005646-xhx9pzhj 685 38 with with IN cord-005646-xhx9pzhj 685 39 miscellaneous miscellaneous JJ cord-005646-xhx9pzhj 685 40 . . . cord-005646-xhx9pzhj 686 1 All all PDT cord-005646-xhx9pzhj 686 2 the the DT cord-005646-xhx9pzhj 686 3 subjects subject NNS cord-005646-xhx9pzhj 686 4 were be VBD cord-005646-xhx9pzhj 686 5 monitorized monitorize VBN cord-005646-xhx9pzhj 686 6 on on IN cord-005646-xhx9pzhj 686 7 PICU PICU NNP cord-005646-xhx9pzhj 686 8 admission admission NN cord-005646-xhx9pzhj 686 9 and and CC cord-005646-xhx9pzhj 686 10 treated treat VBN cord-005646-xhx9pzhj 686 11 for for IN cord-005646-xhx9pzhj 686 12 their -PRON- PRP$ cord-005646-xhx9pzhj 686 13 underlying underlying JJ cord-005646-xhx9pzhj 686 14 condition condition NN cord-005646-xhx9pzhj 686 15 . . . cord-005646-xhx9pzhj 687 1 Gastric gastric JJ cord-005646-xhx9pzhj 687 2 intramucnsal intramucnsal NNS cord-005646-xhx9pzhj 687 3 pt pt NNP cord-005646-xhx9pzhj 687 4 { { -LRB- cord-005646-xhx9pzhj 687 5 was be VBD cord-005646-xhx9pzhj 687 6 measured measure VBN cord-005646-xhx9pzhj 687 7 following follow VBG cord-005646-xhx9pzhj 687 8 the the DT cord-005646-xhx9pzhj 687 9 tonometric tonometric NN cord-005646-xhx9pzhj 687 10 method method NN cord-005646-xhx9pzhj 687 11 , , , cord-005646-xhx9pzhj 687 12 ou ou NNP cord-005646-xhx9pzhj 687 13 admission admission NN cord-005646-xhx9pzhj 687 14 and and CC cord-005646-xhx9pzhj 687 15 every every DT cord-005646-xhx9pzhj 687 16 4 4 CD cord-005646-xhx9pzhj 687 17 - - SYM cord-005646-xhx9pzhj 687 18 8 8 CD cord-005646-xhx9pzhj 687 19 hours hour NNS cord-005646-xhx9pzhj 687 20 depending depend VBG cord-005646-xhx9pzhj 687 21 on on IN cord-005646-xhx9pzhj 687 22 the the DT cord-005646-xhx9pzhj 687 23 patients patient NNS cord-005646-xhx9pzhj 687 24 state state NN cord-005646-xhx9pzhj 687 25 . . . cord-005646-xhx9pzhj 688 1 The the DT cord-005646-xhx9pzhj 688 2 severity severity NN cord-005646-xhx9pzhj 688 3 of of IN cord-005646-xhx9pzhj 688 4 the the DT cord-005646-xhx9pzhj 688 5 clinical clinical JJ cord-005646-xhx9pzhj 688 6 condition condition NN cord-005646-xhx9pzhj 688 7 was be VBD cord-005646-xhx9pzhj 688 8 evaluated evaluate VBN cord-005646-xhx9pzhj 688 9 using use VBG cord-005646-xhx9pzhj 688 10 the the DT cord-005646-xhx9pzhj 688 11 the the DT cord-005646-xhx9pzhj 688 12 PRIMS PRIMS NNP cord-005646-xhx9pzhj 688 13 , , , cord-005646-xhx9pzhj 688 14 on on IN cord-005646-xhx9pzhj 688 15 admission admission NN cord-005646-xhx9pzhj 688 16 ( ( -LRB- cord-005646-xhx9pzhj 688 17 PRIMS PRIMS NNP cord-005646-xhx9pzhj 688 18 - - HYPH cord-005646-xhx9pzhj 688 19 I I NNP cord-005646-xhx9pzhj 688 20 ) ) -RRB- cord-005646-xhx9pzhj 688 21 and and CC cord-005646-xhx9pzhj 688 22 during during IN cord-005646-xhx9pzhj 688 23 the the DT cord-005646-xhx9pzhj 688 24 first first JJ cord-005646-xhx9pzhj 688 25 24 24 CD cord-005646-xhx9pzhj 688 26 hours hour NNS cord-005646-xhx9pzhj 688 27 , , , cord-005646-xhx9pzhj 688 28 when when WRB cord-005646-xhx9pzhj 688 29 the the DT cord-005646-xhx9pzhj 688 30 clinical clinical JJ cord-005646-xhx9pzhj 688 31 condition condition NN cord-005646-xhx9pzhj 688 32 deteriorate deteriorate VBP cord-005646-xhx9pzhj 688 33 , , , cord-005646-xhx9pzhj 688 34 the the DT cord-005646-xhx9pzhj 688 35 worse bad JJR cord-005646-xhx9pzhj 688 36 score score NN cord-005646-xhx9pzhj 688 37 was be VBD cord-005646-xhx9pzhj 688 38 utilized utilize VBN cord-005646-xhx9pzhj 688 39 for for IN cord-005646-xhx9pzhj 688 40 the the DT cord-005646-xhx9pzhj 688 41 statistical statistical JJ cord-005646-xhx9pzhj 688 42 analysis analysis NN cord-005646-xhx9pzhj 688 43 ( ( -LRB- cord-005646-xhx9pzhj 688 44 PRIMS-2 PRIMS-2 NNP cord-005646-xhx9pzhj 688 45 ) ) -RRB- cord-005646-xhx9pzhj 688 46 . . . cord-005646-xhx9pzhj 689 1 To to TO cord-005646-xhx9pzhj 689 2 perform perform VB cord-005646-xhx9pzhj 689 3 the the DT cord-005646-xhx9pzhj 689 4 statistical statistical JJ cord-005646-xhx9pzhj 689 5 analysis analysis NN cord-005646-xhx9pzhj 689 6 the the DT cord-005646-xhx9pzhj 689 7 subjects subject NNS cord-005646-xhx9pzhj 689 8 were be VBD cord-005646-xhx9pzhj 689 9 divided divide VBN cord-005646-xhx9pzhj 689 10 in in IN cord-005646-xhx9pzhj 689 11 two two CD cord-005646-xhx9pzhj 689 12 groups group NNS cord-005646-xhx9pzhj 689 13 , , , cord-005646-xhx9pzhj 689 14 one one CD cord-005646-xhx9pzhj 689 15 with with IN cord-005646-xhx9pzhj 689 16 the the DT cord-005646-xhx9pzhj 689 17 pHi<7.30and phi<7.30and NN cord-005646-xhx9pzhj 690 1 the the DT cord-005646-xhx9pzhj 690 2 other other JJ cord-005646-xhx9pzhj 690 3 with with IN cord-005646-xhx9pzhj 690 4 pHi>7.30.Aunivariate pHi>7.30.Aunivariate NNP cord-005646-xhx9pzhj 690 5 analysis analysis NN cord-005646-xhx9pzhj 691 1 ( ( -LRB- cord-005646-xhx9pzhj 691 2 Student student NN cord-005646-xhx9pzhj 691 3 's 's POS cord-005646-xhx9pzhj 691 4 tand tand NN cord-005646-xhx9pzhj 691 5 Wilcoxon Wilcoxon NNP cord-005646-xhx9pzhj 691 6 two two CD cord-005646-xhx9pzhj 691 7 tailed tailed JJ cord-005646-xhx9pzhj 691 8 test test NN cord-005646-xhx9pzhj 691 9 , , , cord-005646-xhx9pzhj 691 10 chi chi NNP cord-005646-xhx9pzhj 691 11 - - HYPH cord-005646-xhx9pzhj 691 12 square square NNP cord-005646-xhx9pzhj 691 13 ) ) -RRB- cord-005646-xhx9pzhj 691 14 and and CC cord-005646-xhx9pzhj 691 15 multivariate multivariate JJ cord-005646-xhx9pzhj 691 16 analysis analysis NN cord-005646-xhx9pzhj 691 17 were be VBD cord-005646-xhx9pzhj 691 18 used use VBN cord-005646-xhx9pzhj 691 19 . . . cord-005646-xhx9pzhj 692 1 Results result NNS cord-005646-xhx9pzhj 692 2 : : : cord-005646-xhx9pzhj 692 3 12 12 CD cord-005646-xhx9pzhj 692 4 out out IN cord-005646-xhx9pzhj 692 5 of of IN cord-005646-xhx9pzhj 692 6 the the DT cord-005646-xhx9pzhj 692 7 51 51 CD cord-005646-xhx9pzhj 692 8 subjects subject NNS cord-005646-xhx9pzhj 692 9 dyed dye VBN cord-005646-xhx9pzhj 692 10 . . . cord-005646-xhx9pzhj 693 1 Of of IN cord-005646-xhx9pzhj 693 2 14 14 CD cord-005646-xhx9pzhj 693 3 children child NNS cord-005646-xhx9pzhj 693 4 developing develop VBG cord-005646-xhx9pzhj 693 5 multiorgan multiorgan NNP cord-005646-xhx9pzhj 693 6 failure failure NN cord-005646-xhx9pzhj 693 7 ( ( -LRB- cord-005646-xhx9pzhj 693 8 MOF MOF NNP cord-005646-xhx9pzhj 693 9 ) ) -RRB- cord-005646-xhx9pzhj 693 10 9 9 CD cord-005646-xhx9pzhj 693 11 expired expire VBD cord-005646-xhx9pzhj 693 12 . . . cord-005646-xhx9pzhj 694 1 50 50 CD cord-005646-xhx9pzhj 694 2 % % NN cord-005646-xhx9pzhj 694 3 of of IN cord-005646-xhx9pzhj 694 4 the the DT cord-005646-xhx9pzhj 694 5 patients patient NNS cord-005646-xhx9pzhj 694 6 admitted admit VBN cord-005646-xhx9pzhj 694 7 to to IN cord-005646-xhx9pzhj 694 8 the the DT cord-005646-xhx9pzhj 694 9 PICU PICU NNP cord-005646-xhx9pzhj 694 10 with with IN cord-005646-xhx9pzhj 694 11 sepsis sepsis NN cord-005646-xhx9pzhj 694 12 , , , cord-005646-xhx9pzhj 694 13 ARDS ARDS NNP cord-005646-xhx9pzhj 694 14 and and CC cord-005646-xhx9pzhj 694 15 miscellaneous miscellaneous NNP cord-005646-xhx9pzhj 694 16 had have VBD cord-005646-xhx9pzhj 694 17 a a DT cord-005646-xhx9pzhj 694 18 pHi phi JJ cord-005646-xhx9pzhj 694 19 < < XX cord-005646-xhx9pzhj 694 20 7.30 7.30 CD cord-005646-xhx9pzhj 694 21 . . . cord-005646-xhx9pzhj 695 1 In in IN cord-005646-xhx9pzhj 695 2 contrast contrast NN cord-005646-xhx9pzhj 695 3 , , , cord-005646-xhx9pzhj 695 4 with with IN cord-005646-xhx9pzhj 695 5 27 27 CD cord-005646-xhx9pzhj 695 6 % % NN cord-005646-xhx9pzhj 695 7 of of IN cord-005646-xhx9pzhj 695 8 post post JJ cord-005646-xhx9pzhj 695 9 - - JJ cord-005646-xhx9pzhj 695 10 surgical surgical JJ cord-005646-xhx9pzhj 695 11 and and CC cord-005646-xhx9pzhj 695 12 none none NN cord-005646-xhx9pzhj 695 13 of of IN cord-005646-xhx9pzhj 695 14 the the DT cord-005646-xhx9pzhj 695 15 postqraan postqraan NNP cord-005646-xhx9pzhj 695 16 ~ ~ NFP cord-005646-xhx9pzhj 695 17 atism atism NN cord-005646-xhx9pzhj 695 18 . . . cord-005646-xhx9pzhj 696 1 The the DT cord-005646-xhx9pzhj 696 2 mortaliry mortaliry NN cord-005646-xhx9pzhj 696 3 rate rate NN cord-005646-xhx9pzhj 696 4 , , , cord-005646-xhx9pzhj 696 5 in in IN cord-005646-xhx9pzhj 696 6 children child NNS cord-005646-xhx9pzhj 696 7 with with IN cord-005646-xhx9pzhj 696 8 a a DT cord-005646-xhx9pzhj 696 9 pHi<7.30was pHi<7.30was NNP cord-005646-xhx9pzhj 696 10 47 47 CD cord-005646-xhx9pzhj 696 11 % % NN cord-005646-xhx9pzhj 696 12 ( ( -LRB- cord-005646-xhx9pzhj 696 13 CI CI NNP cord-005646-xhx9pzhj 696 14 95%:26.16 95%:26.16 CD cord-005646-xhx9pzhj 696 15 ; ; : cord-005646-xhx9pzhj 696 16 69,04 69,04 CD cord-005646-xhx9pzhj 696 17 ) ) -RRB- cord-005646-xhx9pzhj 696 18 and and CC cord-005646-xhx9pzhj 696 19 11.76 11.76 CD cord-005646-xhx9pzhj 696 20 % % NN cord-005646-xhx9pzhj 696 21 ( ( -LRB- cord-005646-xhx9pzhj 696 22 CI CI NNP cord-005646-xhx9pzhj 696 23 95%:4,67 95%:4,67 NNP cord-005646-xhx9pzhj 696 24 ; ; : cord-005646-xhx9pzhj 696 25 26.62 26.62 CD cord-005646-xhx9pzhj 696 26 ) ) -RRB- cord-005646-xhx9pzhj 696 27 in in IN cord-005646-xhx9pzhj 696 28 children child NNS cord-005646-xhx9pzhj 696 29 with with IN cord-005646-xhx9pzhj 696 30 phi>7.30 phi>7.30 NNS cord-005646-xhx9pzhj 696 31 ( ( -LRB- cord-005646-xhx9pzhj 696 32 p=0.011 p=0.011 NNP cord-005646-xhx9pzhj 696 33 ) ) -RRB- cord-005646-xhx9pzhj 696 34 . . . cord-005646-xhx9pzhj 697 1 MOFwas MOFwas NNP cord-005646-xhx9pzhj 697 2 observed observe VBD cord-005646-xhx9pzhj 697 3 in41,18 in41,18 CD cord-005646-xhx9pzhj 697 4 % % NN cord-005646-xhx9pzhj 697 5 of of IN cord-005646-xhx9pzhj 697 6 children child NNS cord-005646-xhx9pzhj 697 7 withpHi<7.30v.s withpHi<7.30v.s NNP cord-005646-xhx9pzhj 697 8 , , , cord-005646-xhx9pzhj 697 9 20.6 20.6 CD cord-005646-xhx9pzhj 697 10 % % NN cord-005646-xhx9pzhj 697 11 with with IN cord-005646-xhx9pzhj 697 12 phi phi NNP cord-005646-xhx9pzhj 698 1 > > XX cord-005646-xhx9pzhj 699 1 7.30.No 7.30.no CD cord-005646-xhx9pzhj 700 1 relatiouship relatiouship NN cord-005646-xhx9pzhj 700 2 was be VBD cord-005646-xhx9pzhj 700 3 observed observe VBN cord-005646-xhx9pzhj 700 4 between between IN cord-005646-xhx9pzhj 700 5 the the DT cord-005646-xhx9pzhj 700 6 pHi pHi NNS cord-005646-xhx9pzhj 700 7 and and CC cord-005646-xhx9pzhj 700 8 the the DT cord-005646-xhx9pzhj 700 9 score score NN cord-005646-xhx9pzhj 700 10 of of IN cord-005646-xhx9pzhj 700 11 PRIMS PRIMS NNP cord-005646-xhx9pzhj 700 12 - - : cord-005646-xhx9pzhj 700 13 I i NN cord-005646-xhx9pzhj 700 14 and and CC cord-005646-xhx9pzhj 700 15 2 2 CD cord-005646-xhx9pzhj 700 16 . . . cord-005646-xhx9pzhj 701 1 Perforating perforate VBG cord-005646-xhx9pzhj 701 2 an an DT cord-005646-xhx9pzhj 701 3 unconditional unconditional JJ cord-005646-xhx9pzhj 701 4 logistic logistic JJ cord-005646-xhx9pzhj 701 5 regression regression NN cord-005646-xhx9pzhj 701 6 analysis analysis NN cord-005646-xhx9pzhj 701 7 , , , cord-005646-xhx9pzhj 701 8 two two CD cord-005646-xhx9pzhj 701 9 independent independent JJ cord-005646-xhx9pzhj 701 10 variables variable NNS cord-005646-xhx9pzhj 701 11 have have VBP cord-005646-xhx9pzhj 701 12 mortality mortality NN cord-005646-xhx9pzhj 701 13 predictive predictive JJ cord-005646-xhx9pzhj 701 14 value value NN cord-005646-xhx9pzhj 701 15 : : : cord-005646-xhx9pzhj 701 16 the the DT cord-005646-xhx9pzhj 701 17 phi phi NNP cord-005646-xhx9pzhj 701 18 and and CC cord-005646-xhx9pzhj 701 19 the the DT cord-005646-xhx9pzhj 701 20 PRISM-2 PRISM-2 NNP cord-005646-xhx9pzhj 701 21 . . . cord-005646-xhx9pzhj 702 1 ( ( -LRB- cord-005646-xhx9pzhj 702 2 Table table NN cord-005646-xhx9pzhj 702 3 I i CD cord-005646-xhx9pzhj 702 4 ) ) -RRB- cord-005646-xhx9pzhj 703 1 Following follow VBG cord-005646-xhx9pzhj 703 2 induction induction NN cord-005646-xhx9pzhj 703 3 of of IN cord-005646-xhx9pzhj 703 4 anaesthesia anaesthesia NN cord-005646-xhx9pzhj 703 5 , , , cord-005646-xhx9pzhj 703 6 a a DT cord-005646-xhx9pzhj 703 7 laser laser NN cord-005646-xhx9pzhj 703 8 Doppler doppler NN cord-005646-xhx9pzhj 703 9 probe probe NN cord-005646-xhx9pzhj 703 10 ( ( -LRB- cord-005646-xhx9pzhj 703 11 Moorsoft Moorsoft NNP cord-005646-xhx9pzhj 703 12 Instruments Instruments NNPS cord-005646-xhx9pzhj 703 13 Ltd Ltd NNP cord-005646-xhx9pzhj 703 14 ) ) -RRB- cord-005646-xhx9pzhj 703 15 was be VBD cord-005646-xhx9pzhj 703 16 inserted insert VBN cord-005646-xhx9pzhj 703 17 7 7 CD cord-005646-xhx9pzhj 703 18 cm cm NNS cord-005646-xhx9pzhj 703 19 into into IN cord-005646-xhx9pzhj 703 20 the the DT cord-005646-xhx9pzhj 703 21 patient patient NN cord-005646-xhx9pzhj 703 22 's 's POS cord-005646-xhx9pzhj 703 23 rectum rectum NN cord-005646-xhx9pzhj 703 24 , , , cord-005646-xhx9pzhj 703 25 the the DT cord-005646-xhx9pzhj 703 26 probe probe NN cord-005646-xhx9pzhj 703 27 's 's POS cord-005646-xhx9pzhj 703 28 special special JJ cord-005646-xhx9pzhj 703 29 design design NN cord-005646-xhx9pzhj 703 30 ensuring ensure VBG cord-005646-xhx9pzhj 703 31 that that IN cord-005646-xhx9pzhj 703 32 the the DT cord-005646-xhx9pzhj 703 33 optical optical JJ cord-005646-xhx9pzhj 703 34 prism prism NN cord-005646-xhx9pzhj 703 35 lay lie VBD cord-005646-xhx9pzhj 703 36 against against IN cord-005646-xhx9pzhj 703 37 the the DT cord-005646-xhx9pzhj 703 38 mucosa mucosa NN cord-005646-xhx9pzhj 703 39 . . . cord-005646-xhx9pzhj 704 1 Continuous continuous JJ cord-005646-xhx9pzhj 704 2 monitoring monitoring NN cord-005646-xhx9pzhj 704 3 of of IN cord-005646-xhx9pzhj 704 4 rectal rectal JJ cord-005646-xhx9pzhj 704 5 mucosal mucosal JJ cord-005646-xhx9pzhj 704 6 perfusion perfusion NN cord-005646-xhx9pzhj 704 7 ( ( -LRB- cord-005646-xhx9pzhj 704 8 " " `` cord-005646-xhx9pzhj 704 9 flux flux NN cord-005646-xhx9pzhj 704 10 " " '' cord-005646-xhx9pzhj 704 11 ) ) -RRB- cord-005646-xhx9pzhj 704 12 was be VBD cord-005646-xhx9pzhj 704 13 continued continue VBN cord-005646-xhx9pzhj 704 14 throughout throughout IN cord-005646-xhx9pzhj 704 15 the the DT cord-005646-xhx9pzhj 704 16 operation operation NN cord-005646-xhx9pzhj 704 17 . . . cord-005646-xhx9pzhj 705 1 After after IN cord-005646-xhx9pzhj 705 2 10 10 CD cord-005646-xhx9pzhj 705 3 rain rain NN cord-005646-xhx9pzhj 705 4 CPB CPB NNP cord-005646-xhx9pzhj 705 5 at at IN cord-005646-xhx9pzhj 705 6 35 35 CD cord-005646-xhx9pzhj 705 7 ° ° NN cord-005646-xhx9pzhj 705 8 C c NN cord-005646-xhx9pzhj 705 9 , , , cord-005646-xhx9pzhj 705 10 " " '' cord-005646-xhx9pzhj 705 11 steady steady JJ cord-005646-xhx9pzhj 705 12 state state NN cord-005646-xhx9pzhj 705 13 " " '' cord-005646-xhx9pzhj 705 14 readings reading NNS cord-005646-xhx9pzhj 705 15 of of IN cord-005646-xhx9pzhj 705 16 nasopharyngeal nasopharyngeal JJ cord-005646-xhx9pzhj 705 17 temperature temperature NN cord-005646-xhx9pzhj 705 18 , , , cord-005646-xhx9pzhj 705 19 mean mean JJ cord-005646-xhx9pzhj 705 20 femoral femoral JJ cord-005646-xhx9pzhj 705 21 arterial arterial JJ cord-005646-xhx9pzhj 705 22 pressure pressure NN cord-005646-xhx9pzhj 705 23 ( ( -LRB- cord-005646-xhx9pzhj 705 24 MAP MAP NNP cord-005646-xhx9pzhj 705 25 ) ) -RRB- cord-005646-xhx9pzhj 705 26 and and CC cord-005646-xhx9pzhj 705 27 flux flux NN cord-005646-xhx9pzhj 705 28 were be VBD cord-005646-xhx9pzhj 705 29 recorded record VBN cord-005646-xhx9pzhj 705 30 over over IN cord-005646-xhx9pzhj 705 31 a a DT cord-005646-xhx9pzhj 705 32 further further JJ cord-005646-xhx9pzhj 705 33 5 5 CD cord-005646-xhx9pzhj 705 34 min min NN cord-005646-xhx9pzhj 705 35 before before IN cord-005646-xhx9pzhj 705 36 CPBinduced CPBinduced NNP cord-005646-xhx9pzhj 705 37 core core NN cord-005646-xhx9pzhj 705 38 cooling cool VBG cord-005646-xhx9pzhj 705 39 to to IN cord-005646-xhx9pzhj 705 40 14 14 CD cord-005646-xhx9pzhj 705 41 - - SYM cord-005646-xhx9pzhj 705 42 24 24 CD cord-005646-xhx9pzhj 705 43 ° ° NN cord-005646-xhx9pzhj 705 44 C c NN cord-005646-xhx9pzhj 705 45 . . . cord-005646-xhx9pzhj 706 1 Steady steady JJ cord-005646-xhx9pzhj 706 2 state state NN cord-005646-xhx9pzhj 706 3 was be VBD cord-005646-xhx9pzhj 706 4 defined define VBN cord-005646-xhx9pzhj 706 5 as as IN cord-005646-xhx9pzhj 706 6 a a DT cord-005646-xhx9pzhj 706 7 5 5 CD cord-005646-xhx9pzhj 706 8 rain rain NN cord-005646-xhx9pzhj 706 9 period period NN cord-005646-xhx9pzhj 706 10 with with IN cord-005646-xhx9pzhj 706 11 no no DT cord-005646-xhx9pzhj 706 12 change change NN cord-005646-xhx9pzhj 706 13 in in IN cord-005646-xhx9pzhj 706 14 core core NN cord-005646-xhx9pzhj 706 15 temperatures temperature NNS cord-005646-xhx9pzhj 706 16 or or CC cord-005646-xhx9pzhj 706 17 MAP map NN cord-005646-xhx9pzhj 706 18 . . . cord-005646-xhx9pzhj 707 1 Other other JJ cord-005646-xhx9pzhj 707 2 5 5 CD cord-005646-xhx9pzhj 707 3 rain rain VBP cord-005646-xhx9pzhj 707 4 steady steady JJ cord-005646-xhx9pzhj 707 5 state state NN cord-005646-xhx9pzhj 707 6 recordings recording NNS cord-005646-xhx9pzhj 707 7 were be VBD cord-005646-xhx9pzhj 707 8 taken take VBN cord-005646-xhx9pzhj 707 9 immediately immediately RB cord-005646-xhx9pzhj 707 10 prior prior RB cord-005646-xhx9pzhj 707 11 to to IN cord-005646-xhx9pzhj 707 12 low low JJ cord-005646-xhx9pzhj 707 13 flow flow NN cord-005646-xhx9pzhj 707 14 , , , cord-005646-xhx9pzhj 707 15 immediately immediately RB cord-005646-xhx9pzhj 707 16 prior prior RB cord-005646-xhx9pzhj 707 17 to to IN cord-005646-xhx9pzhj 707 18 rewarming rewarming NN cord-005646-xhx9pzhj 707 19 and and CC cord-005646-xhx9pzhj 707 20 after after IN cord-005646-xhx9pzhj 707 21 rewarming rewarme VBG cord-005646-xhx9pzhj 707 22 to to IN cord-005646-xhx9pzhj 707 23 35 35 CD cord-005646-xhx9pzhj 707 24 ° ° NN cord-005646-xhx9pzhj 707 25 C c NN cord-005646-xhx9pzhj 707 26 , , , cord-005646-xhx9pzhj 707 27 before before IN cord-005646-xhx9pzhj 707 28 initiation initiation NN cord-005646-xhx9pzhj 707 29 of of IN cord-005646-xhx9pzhj 707 30 any any DT cord-005646-xhx9pzhj 707 31 vasoactive vasoactive JJ cord-005646-xhx9pzhj 707 32 drugs drug NNS cord-005646-xhx9pzhj 707 33 . . . cord-005646-xhx9pzhj 708 1 The the DT cord-005646-xhx9pzhj 708 2 CPB CPB NNP cord-005646-xhx9pzhj 708 3 flow flow NN cord-005646-xhx9pzhj 708 4 rate rate NN cord-005646-xhx9pzhj 708 5 was be VBD cord-005646-xhx9pzhj 708 6 kept keep VBN cord-005646-xhx9pzhj 708 7 at at IN cord-005646-xhx9pzhj 708 8 100 100 CD cord-005646-xhx9pzhj 708 9 m m NN cord-005646-xhx9pzhj 708 10 l l NN cord-005646-xhx9pzhj 708 11 k k NNP cord-005646-xhx9pzhj 708 12 g g NNP cord-005646-xhx9pzhj 708 13 -1 -1 NN cord-005646-xhx9pzhj 708 14 min min NNP cord-005646-xhx9pzhj 708 15 q q NNP cord-005646-xhx9pzhj 708 16 , , , cord-005646-xhx9pzhj 708 17 the the DT cord-005646-xhx9pzhj 708 18 PCV PCV NNP cord-005646-xhx9pzhj 708 19 at at IN cord-005646-xhx9pzhj 708 20 25_+3 25_+3 CD cord-005646-xhx9pzhj 708 21 % % NN cord-005646-xhx9pzhj 708 22 , , , cord-005646-xhx9pzhj 708 23 the the DT cord-005646-xhx9pzhj 708 24 P p NN cord-005646-xhx9pzhj 708 25 ~ ~ CD cord-005646-xhx9pzhj 708 26 CO co NN cord-005646-xhx9pzhj 708 27 2 2 CD cord-005646-xhx9pzhj 708 28 at at IN cord-005646-xhx9pzhj 708 29 5.3 5.3 CD cord-005646-xhx9pzhj 708 30 + + SYM cord-005646-xhx9pzhj 708 31 0.5 0.5 CD cord-005646-xhx9pzhj 708 32 kPa kPa NNS cord-005646-xhx9pzhj 708 33 and and CC cord-005646-xhx9pzhj 708 34 the the DT cord-005646-xhx9pzhj 708 35 PrO2 pro2 NN cord-005646-xhx9pzhj 708 36 at at IN cord-005646-xhx9pzhj 708 37 20 20 CD cord-005646-xhx9pzhj 708 38 + + SYM cord-005646-xhx9pzhj 708 39 5 5 CD cord-005646-xhx9pzhj 708 40 kPa kPa NNS cord-005646-xhx9pzhj 708 41 . . . cord-005646-xhx9pzhj 709 1 Results result NNS cord-005646-xhx9pzhj 709 2 : : : cord-005646-xhx9pzhj 710 1 Initial initial JJ cord-005646-xhx9pzhj 710 2 warm warm NN cord-005646-xhx9pzhj 710 3 and and CC cord-005646-xhx9pzhj 710 4 rewarm rewarm VB cord-005646-xhx9pzhj 710 5 MAP MAP NNP cord-005646-xhx9pzhj 710 6 ( ( -LRB- cord-005646-xhx9pzhj 710 7 both both DT cord-005646-xhx9pzhj 710 8 46 46 CD cord-005646-xhx9pzhj 710 9 mmHg mmHg NNS cord-005646-xhx9pzhj 710 10 ) ) -RRB- cord-005646-xhx9pzhj 710 11 were be VBD cord-005646-xhx9pzhj 710 12 significantly significantly RB cord-005646-xhx9pzhj 710 13 lower low JJR cord-005646-xhx9pzhj 710 14 ( ( -LRB- cord-005646-xhx9pzhj 710 15 19=0.008 19=0.008 CD cord-005646-xhx9pzhj 710 16 ) ) -RRB- cord-005646-xhx9pzhj 710 17 than than IN cord-005646-xhx9pzhj 710 18 during during IN cord-005646-xhx9pzhj 710 19 the the DT cord-005646-xhx9pzhj 710 20 2 2 CD cord-005646-xhx9pzhj 710 21 cold cold JJ cord-005646-xhx9pzhj 710 22 CPB CPB NNP cord-005646-xhx9pzhj 710 23 periods period NNS cord-005646-xhx9pzhj 710 24 ( ( -LRB- cord-005646-xhx9pzhj 710 25 63 63 CD cord-005646-xhx9pzhj 710 26 & & CC cord-005646-xhx9pzhj 710 27 64 64 CD cord-005646-xhx9pzhj 710 28 mmHg mmHg NNS cord-005646-xhx9pzhj 710 29 ) ) -RRB- cord-005646-xhx9pzhj 710 30 . . . cord-005646-xhx9pzhj 711 1 The the DT cord-005646-xhx9pzhj 711 2 mean mean JJ cord-005646-xhx9pzhj 711 3 cold cold JJ cord-005646-xhx9pzhj 711 4 flux flux NN cord-005646-xhx9pzhj 711 5 before before IN cord-005646-xhx9pzhj 711 6 ( ( -LRB- cord-005646-xhx9pzhj 711 7 152 152 CD cord-005646-xhx9pzhj 711 8 ) ) -RRB- cord-005646-xhx9pzhj 711 9 and and CC cord-005646-xhx9pzhj 711 10 after after IN cord-005646-xhx9pzhj 711 11 ( ( -LRB- cord-005646-xhx9pzhj 711 12 159 159 CD cord-005646-xhx9pzhj 711 13 ) ) -RRB- cord-005646-xhx9pzhj 711 14 low low JJ cord-005646-xhx9pzhj 711 15 flow flow NN cord-005646-xhx9pzhj 711 16 were be VBD cord-005646-xhx9pzhj 711 17 both both DT cord-005646-xhx9pzhj 711 18 significantly significantly RB cord-005646-xhx9pzhj 711 19 lower lower RBR cord-005646-xhx9pzhj 711 20 ( ( -LRB- cord-005646-xhx9pzhj 711 21 p=0.001 p=0.001 NNS cord-005646-xhx9pzhj 711 22 ) ) -RRB- cord-005646-xhx9pzhj 711 23 than than IN cord-005646-xhx9pzhj 711 24 the the DT cord-005646-xhx9pzhj 711 25 mean mean JJ cord-005646-xhx9pzhj 711 26 initial initial JJ cord-005646-xhx9pzhj 711 27 warm warm JJ cord-005646-xhx9pzhj 711 28 CPB CPB NNP cord-005646-xhx9pzhj 711 29 flux flux NN cord-005646-xhx9pzhj 711 30 ( ( -LRB- cord-005646-xhx9pzhj 711 31 211 211 CD cord-005646-xhx9pzhj 711 32 ) ) -RRB- cord-005646-xhx9pzhj 711 33 . . . cord-005646-xhx9pzhj 712 1 The the DT cord-005646-xhx9pzhj 712 2 mean mean NN cord-005646-xhx9pzhj 712 3 rewarm rewarm VBP cord-005646-xhx9pzhj 712 4 CPB CPB NNP cord-005646-xhx9pzhj 712 5 flux flux NN cord-005646-xhx9pzhj 712 6 ( ( -LRB- cord-005646-xhx9pzhj 712 7 127 127 CD cord-005646-xhx9pzhj 712 8 ) ) -RRB- cord-005646-xhx9pzhj 712 9 was be VBD cord-005646-xhx9pzhj 712 10 significantly significantly RB cord-005646-xhx9pzhj 712 11 lower low JJR cord-005646-xhx9pzhj 712 12 than than IN cord-005646-xhx9pzhj 712 13 all all DT cord-005646-xhx9pzhj 712 14 other other JJ cord-005646-xhx9pzhj 712 15 flux flux NN cord-005646-xhx9pzhj 712 16 values value NNS cord-005646-xhx9pzhj 712 17 ( ( -LRB- cord-005646-xhx9pzhj 712 18 p=0.001 p=0.001 NNP cord-005646-xhx9pzhj 712 19 ) ) -RRB- cord-005646-xhx9pzhj 712 20 . . . cord-005646-xhx9pzhj 713 1 There there EX cord-005646-xhx9pzhj 713 2 were be VBD cord-005646-xhx9pzhj 713 3 no no DT cord-005646-xhx9pzhj 713 4 siglaificant siglaificant JJ cord-005646-xhx9pzhj 713 5 correlations correlation NNS cord-005646-xhx9pzhj 713 6 between between IN cord-005646-xhx9pzhj 713 7 MAP map NN cord-005646-xhx9pzhj 713 8 and and CC cord-005646-xhx9pzhj 713 9 flux flux NN cord-005646-xhx9pzhj 713 10 except except IN cord-005646-xhx9pzhj 713 11 at at IN cord-005646-xhx9pzhj 713 12 the the DT cord-005646-xhx9pzhj 713 13 first first JJ cord-005646-xhx9pzhj 713 14 warm warm JJ cord-005646-xhx9pzhj 713 15 CPB CPB NNP cord-005646-xhx9pzhj 713 16 period period NN cord-005646-xhx9pzhj 713 17 ( ( -LRB- cord-005646-xhx9pzhj 713 18 r=0,33 r=0,33 NNP cord-005646-xhx9pzhj 713 19 , , , cord-005646-xhx9pzhj 713 20 p=0.04 p=0.04 NNP cord-005646-xhx9pzhj 713 21 ) ) -RRB- cord-005646-xhx9pzhj 713 22 . . . cord-005646-xhx9pzhj 714 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 714 2 : : : cord-005646-xhx9pzhj 715 1 Although although IN cord-005646-xhx9pzhj 715 2 hypothermia hypothermia NN cord-005646-xhx9pzhj 715 3 significantly significantly RB cord-005646-xhx9pzhj 715 4 reduces reduce VBZ cord-005646-xhx9pzhj 715 5 rectal rectal JJ cord-005646-xhx9pzhj 715 6 mucosal mucosal JJ cord-005646-xhx9pzhj 715 7 perfusion perfusion NN cord-005646-xhx9pzhj 715 8 , , , cord-005646-xhx9pzhj 715 9 rewarming rewarming NNP cord-005646-xhx9pzhj 715 10 produces produce VBZ cord-005646-xhx9pzhj 715 11 an an DT cord-005646-xhx9pzhj 715 12 even even RB cord-005646-xhx9pzhj 715 13 greater great JJR cord-005646-xhx9pzhj 715 14 reduction reduction NN cord-005646-xhx9pzhj 715 15 in in IN cord-005646-xhx9pzhj 715 16 gut gut NN cord-005646-xhx9pzhj 715 17 perfusion perfusion NN cord-005646-xhx9pzhj 715 18 which which WDT cord-005646-xhx9pzhj 715 19 , , , cord-005646-xhx9pzhj 715 20 considering consider VBG cord-005646-xhx9pzhj 715 21 that that IN cord-005646-xhx9pzhj 715 22 mucosal mucosal JJ cord-005646-xhx9pzhj 715 23 oxygen oxygen NN cord-005646-xhx9pzhj 715 24 constmaption constmaption NN cord-005646-xhx9pzhj 715 25 is be VBZ cord-005646-xhx9pzhj 715 26 highest high JJS cord-005646-xhx9pzhj 715 27 during during IN cord-005646-xhx9pzhj 715 28 this this DT cord-005646-xhx9pzhj 715 29 time time NN cord-005646-xhx9pzhj 715 30 , , , cord-005646-xhx9pzhj 715 31 may may MD cord-005646-xhx9pzhj 715 32 prove prove VB cord-005646-xhx9pzhj 715 33 crucial crucial JJ cord-005646-xhx9pzhj 715 34 in in IN cord-005646-xhx9pzhj 715 35 the the DT cord-005646-xhx9pzhj 715 36 postoperative postoperative JJ cord-005646-xhx9pzhj 715 37 development development NN cord-005646-xhx9pzhj 715 38 of of IN cord-005646-xhx9pzhj 715 39 MOF MOF NNP cord-005646-xhx9pzhj 715 40 . . . cord-005646-xhx9pzhj 716 1 Therapy therapy NN cord-005646-xhx9pzhj 716 2 aimed aim VBN cord-005646-xhx9pzhj 716 3 at at IN cord-005646-xhx9pzhj 716 4 improving improve VBG cord-005646-xhx9pzhj 716 5 gut gut NN cord-005646-xhx9pzhj 716 6 perfusion perfusion NN cord-005646-xhx9pzhj 716 7 during during IN cord-005646-xhx9pzhj 716 8 CPB CPB NNP cord-005646-xhx9pzhj 716 9 should should MD cord-005646-xhx9pzhj 716 10 be be VB cord-005646-xhx9pzhj 716 11 directed direct VBN cord-005646-xhx9pzhj 716 12 at at IN cord-005646-xhx9pzhj 716 13 the the DT cord-005646-xhx9pzhj 716 14 rewanning rewanne VBG cord-005646-xhx9pzhj 716 15 period period NN cord-005646-xhx9pzhj 716 16 in in IN cord-005646-xhx9pzhj 716 17 particular particular JJ cord-005646-xhx9pzhj 716 18 . . . cord-005646-xhx9pzhj 717 1 ABSTRACT ABSTRACT NNP cord-005646-xhx9pzhj 718 1 This this DT cord-005646-xhx9pzhj 718 2 work work NN cord-005646-xhx9pzhj 718 3 is be VBZ cord-005646-xhx9pzhj 718 4 aimed aim VBN cord-005646-xhx9pzhj 718 5 at at IN cord-005646-xhx9pzhj 718 6 establishing establish VBG cord-005646-xhx9pzhj 718 7 a a DT cord-005646-xhx9pzhj 718 8 clinical clinical JJ cord-005646-xhx9pzhj 718 9 procedure procedure NN cord-005646-xhx9pzhj 718 10 for for IN cord-005646-xhx9pzhj 718 11 the the DT cord-005646-xhx9pzhj 718 12 diagnosis diagnosis NN cord-005646-xhx9pzhj 718 13 of of IN cord-005646-xhx9pzhj 718 14 Enteritis Enteritis NNP cord-005646-xhx9pzhj 718 15 necroticans necrotican NNS cord-005646-xhx9pzhj 718 16 ( ( -LRB- cord-005646-xhx9pzhj 718 17 EN EN NNP cord-005646-xhx9pzhj 718 18 ) ) -RRB- cord-005646-xhx9pzhj 718 19 , , , cord-005646-xhx9pzhj 718 20 even even RB cord-005646-xhx9pzhj 718 21 at at IN cord-005646-xhx9pzhj 718 22 the the DT cord-005646-xhx9pzhj 718 23 communal communal JJ cord-005646-xhx9pzhj 718 24 level level NN cord-005646-xhx9pzhj 718 25 , , , cord-005646-xhx9pzhj 718 26 and and CC cord-005646-xhx9pzhj 718 27 to to TO cord-005646-xhx9pzhj 718 28 define define VB cord-005646-xhx9pzhj 718 29 criteria criterion NNS cord-005646-xhx9pzhj 718 30 for for IN cord-005646-xhx9pzhj 718 31 diagnosis diagnosis NN cord-005646-xhx9pzhj 718 32 able able JJ cord-005646-xhx9pzhj 718 33 to to TO cord-005646-xhx9pzhj 718 34 distinguish distinguish VB cord-005646-xhx9pzhj 718 35 between between IN cord-005646-xhx9pzhj 718 36 acute acute JJ cord-005646-xhx9pzhj 718 37 forms form NNS cord-005646-xhx9pzhj 718 38 . . . cord-005646-xhx9pzhj 719 1 SUBJECTS subject NNS cord-005646-xhx9pzhj 719 2 AND and CC cord-005646-xhx9pzhj 719 3 METHOD method NN cord-005646-xhx9pzhj 720 1 : : : cord-005646-xhx9pzhj 720 2 100 100 CD cord-005646-xhx9pzhj 720 3 cases case NNS cord-005646-xhx9pzhj 720 4 admitted admit VBN cord-005646-xhx9pzhj 720 5 at at IN cord-005646-xhx9pzhj 720 6 the the DT cord-005646-xhx9pzhj 720 7 Institute Institute NNP cord-005646-xhx9pzhj 720 8 for for IN cord-005646-xhx9pzhj 720 9 Protection Protection NNP cord-005646-xhx9pzhj 720 10 of of IN cord-005646-xhx9pzhj 720 11 Children Children NNP cord-005646-xhx9pzhj 720 12 's 's POS cord-005646-xhx9pzhj 720 13 Health Health NNP cord-005646-xhx9pzhj 720 14 dPCH dPCH NNP cord-005646-xhx9pzhj 720 15 ) ) -RRB- cord-005646-xhx9pzhj 720 16 , , , cord-005646-xhx9pzhj 720 17 having have VBG cord-005646-xhx9pzhj 720 18 characteristic characteristic JJ cord-005646-xhx9pzhj 720 19 symptoms symptom NNS cord-005646-xhx9pzhj 720 20 , , , cord-005646-xhx9pzhj 720 21 were be VBD cord-005646-xhx9pzhj 720 22 examined examine VBN cord-005646-xhx9pzhj 720 23 clinically clinically RB cord-005646-xhx9pzhj 720 24 , , , cord-005646-xhx9pzhj 720 25 by by IN cord-005646-xhx9pzhj 720 26 roentgenography roentgenography NN cord-005646-xhx9pzhj 720 27 of of IN cord-005646-xhx9pzhj 720 28 the the DT cord-005646-xhx9pzhj 720 29 abdominal abdominal JJ cord-005646-xhx9pzhj 720 30 cavity cavity NN cord-005646-xhx9pzhj 720 31 , , , cord-005646-xhx9pzhj 720 32 with with IN cord-005646-xhx9pzhj 720 33 the the DT cord-005646-xhx9pzhj 720 34 analysis analysis NN cord-005646-xhx9pzhj 720 35 of of IN cord-005646-xhx9pzhj 720 36 the the DT cord-005646-xhx9pzhj 720 37 blood blood NN cord-005646-xhx9pzhj 720 38 ( ( -LRB- cord-005646-xhx9pzhj 720 39 total total JJ cord-005646-xhx9pzhj 720 40 protein protein NN cord-005646-xhx9pzhj 720 41 , , , cord-005646-xhx9pzhj 720 42 electrolytes electrolyte NNS cord-005646-xhx9pzhj 720 43 , , , cord-005646-xhx9pzhj 720 44 hematocrite hematocrite NNP cord-005646-xhx9pzhj 720 45 ) ) -RRB- cord-005646-xhx9pzhj 720 46 and and CC cord-005646-xhx9pzhj 720 47 cultures culture NNS cord-005646-xhx9pzhj 720 48 of of IN cord-005646-xhx9pzhj 720 49 intestinal intestinal JJ cord-005646-xhx9pzhj 720 50 fluid fluid NN cord-005646-xhx9pzhj 720 51 and and CC cord-005646-xhx9pzhj 720 52 faeces faece NNS cord-005646-xhx9pzhj 720 53 . . . cord-005646-xhx9pzhj 721 1 Through through IN cord-005646-xhx9pzhj 721 2 surgical surgical JJ cord-005646-xhx9pzhj 721 3 operations operation NNS cord-005646-xhx9pzhj 721 4 , , , cord-005646-xhx9pzhj 721 5 the the DT cord-005646-xhx9pzhj 721 6 pathological pathological JJ cord-005646-xhx9pzhj 721 7 lesions lesion NNS cord-005646-xhx9pzhj 721 8 were be VBD cord-005646-xhx9pzhj 721 9 observed observe VBN cord-005646-xhx9pzhj 721 10 and and CC cord-005646-xhx9pzhj 721 11 recorded record VBN cord-005646-xhx9pzhj 721 12 . . . cord-005646-xhx9pzhj 722 1 RESULTS result NNS cord-005646-xhx9pzhj 722 2 : : : cord-005646-xhx9pzhj 723 1 Common common JJ cord-005646-xhx9pzhj 723 2 epidemiological epidemiological JJ cord-005646-xhx9pzhj 723 3 features feature NNS cord-005646-xhx9pzhj 724 1 : : : cord-005646-xhx9pzhj 724 2 the the DT cord-005646-xhx9pzhj 724 3 average average JJ cord-005646-xhx9pzhj 724 4 age age NN cord-005646-xhx9pzhj 724 5 is be VBZ cord-005646-xhx9pzhj 724 6 6 6 CD cord-005646-xhx9pzhj 724 7 - - SYM cord-005646-xhx9pzhj 724 8 8 8 CD cord-005646-xhx9pzhj 724 9 years year NNS cord-005646-xhx9pzhj 724 10 old old JJ cord-005646-xhx9pzhj 724 11 ( ( -LRB- cord-005646-xhx9pzhj 724 12 3 3 CD cord-005646-xhx9pzhj 724 13 - - SYM cord-005646-xhx9pzhj 724 14 15 15 CD cord-005646-xhx9pzhj 724 15 ) ) -RRB- cord-005646-xhx9pzhj 724 16 ; ; : cord-005646-xhx9pzhj 724 17 male male JJ cord-005646-xhx9pzhj 724 18 / / SYM cord-005646-xhx9pzhj 724 19 female female JJ cord-005646-xhx9pzhj 724 20 : : : cord-005646-xhx9pzhj 724 21 1.85 1.85 CD cord-005646-xhx9pzhj 724 22 ; ; : cord-005646-xhx9pzhj 724 23 In in IN cord-005646-xhx9pzhj 724 24 70 70 CD cord-005646-xhx9pzhj 724 25 % % NN cord-005646-xhx9pzhj 724 26 of of IN cord-005646-xhx9pzhj 724 27 the the DT cord-005646-xhx9pzhj 724 28 cases case NNS cord-005646-xhx9pzhj 724 29 , , , cord-005646-xhx9pzhj 724 30 the the DT cord-005646-xhx9pzhj 724 31 disease disease NN cord-005646-xhx9pzhj 724 32 occurred occur VBD cord-005646-xhx9pzhj 724 33 after after IN cord-005646-xhx9pzhj 724 34 a a DT cord-005646-xhx9pzhj 724 35 meal meal NN cord-005646-xhx9pzhj 724 36 rich rich JJ cord-005646-xhx9pzhj 724 37 in in IN cord-005646-xhx9pzhj 724 38 protides protide NNS cord-005646-xhx9pzhj 724 39 . . . cord-005646-xhx9pzhj 725 1 The the DT cord-005646-xhx9pzhj 725 2 acute acute JJ cord-005646-xhx9pzhj 725 3 toxic toxic JJ cord-005646-xhx9pzhj 725 4 form form NN cord-005646-xhx9pzhj 725 5 accounted account VBD cord-005646-xhx9pzhj 725 6 for for IN cord-005646-xhx9pzhj 725 7 15 15 CD cord-005646-xhx9pzhj 725 8 % % NN cord-005646-xhx9pzhj 725 9 : : : cord-005646-xhx9pzhj 725 10 severe severe JJ cord-005646-xhx9pzhj 725 11 shock shock NN cord-005646-xhx9pzhj 725 12 appearing appear VBG cord-005646-xhx9pzhj 725 13 early early RB cord-005646-xhx9pzhj 725 14 , , , cord-005646-xhx9pzhj 725 15 with with IN cord-005646-xhx9pzhj 725 16 very very RB cord-005646-xhx9pzhj 725 17 severe severe JJ cord-005646-xhx9pzhj 725 18 dehydration dehydration NN cord-005646-xhx9pzhj 725 19 associated associate VBN cord-005646-xhx9pzhj 725 20 with with IN cord-005646-xhx9pzhj 725 21 profoundly profoundly RB cord-005646-xhx9pzhj 725 22 decreased decrease VBN cord-005646-xhx9pzhj 725 23 blood blood NN cord-005646-xhx9pzhj 725 24 protein protein NN cord-005646-xhx9pzhj 725 25 concentration concentration NN cord-005646-xhx9pzhj 725 26 and and CC cord-005646-xhx9pzhj 725 27 lowered lower VBD cord-005646-xhx9pzhj 725 28 natriemia natriemia NN cord-005646-xhx9pzhj 725 29 as as RB cord-005646-xhx9pzhj 725 30 well well RB cord-005646-xhx9pzhj 725 31 . . . cord-005646-xhx9pzhj 726 1 The the DT cord-005646-xhx9pzhj 726 2 lesions lesion NNS cord-005646-xhx9pzhj 726 3 of of IN cord-005646-xhx9pzhj 726 4 the the DT cord-005646-xhx9pzhj 726 5 small small JJ cord-005646-xhx9pzhj 726 6 intestine intestine NN cord-005646-xhx9pzhj 726 7 were be VBD cord-005646-xhx9pzhj 726 8 expanded expand VBN cord-005646-xhx9pzhj 726 9 , , , cord-005646-xhx9pzhj 726 10 all all DT cord-005646-xhx9pzhj 726 11 of of IN cord-005646-xhx9pzhj 726 12 them -PRON- PRP cord-005646-xhx9pzhj 726 13 were be VBD cord-005646-xhx9pzhj 726 14 necrotic necrotic JJ cord-005646-xhx9pzhj 726 15 . . . cord-005646-xhx9pzhj 727 1 In in IN cord-005646-xhx9pzhj 727 2 the the DT cord-005646-xhx9pzhj 727 3 surgical surgical JJ cord-005646-xhx9pzhj 727 4 form form NN cord-005646-xhx9pzhj 727 5 ( ( -LRB- cord-005646-xhx9pzhj 727 6 20 20 CD cord-005646-xhx9pzhj 727 7 % % NN cord-005646-xhx9pzhj 727 8 ) ) -RRB- cord-005646-xhx9pzhj 727 9 , , , cord-005646-xhx9pzhj 727 10 the the DT cord-005646-xhx9pzhj 727 11 predominant predominant JJ cord-005646-xhx9pzhj 727 12 feature feature NN cord-005646-xhx9pzhj 727 13 was be VBD cord-005646-xhx9pzhj 727 14 an an DT cord-005646-xhx9pzhj 727 15 obstruction obstruction NN cord-005646-xhx9pzhj 727 16 -peritonitis -peritonitis NN cord-005646-xhx9pzhj 727 17 syndrome syndrome NN cord-005646-xhx9pzhj 727 18 , , , cord-005646-xhx9pzhj 727 19 the the DT cord-005646-xhx9pzhj 727 20 peritoneal peritoneal JJ cord-005646-xhx9pzhj 727 21 fluid fluid NN cord-005646-xhx9pzhj 727 22 showed show VBD cord-005646-xhx9pzhj 727 23 a a DT cord-005646-xhx9pzhj 727 24 characteristic characteristic JJ cord-005646-xhx9pzhj 727 25 inflammatory inflammatory JJ cord-005646-xhx9pzhj 727 26 reaction reaction NN cord-005646-xhx9pzhj 727 27 . . . cord-005646-xhx9pzhj 728 1 For for IN cord-005646-xhx9pzhj 728 2 the the DT cord-005646-xhx9pzhj 728 3 rest rest NN cord-005646-xhx9pzhj 728 4 of of IN cord-005646-xhx9pzhj 728 5 cases case NNS cord-005646-xhx9pzhj 728 6 65 65 CD cord-005646-xhx9pzhj 728 7 % % NN cord-005646-xhx9pzhj 728 8 were be VBD cord-005646-xhx9pzhj 728 9 the the DT cord-005646-xhx9pzhj 728 10 internal internal JJ cord-005646-xhx9pzhj 728 11 form form NN cord-005646-xhx9pzhj 728 12 , , , cord-005646-xhx9pzhj 728 13 the the DT cord-005646-xhx9pzhj 728 14 shock shock NN cord-005646-xhx9pzhj 728 15 syndrome syndrome NN cord-005646-xhx9pzhj 728 16 was be VBD cord-005646-xhx9pzhj 728 17 less less RBR cord-005646-xhx9pzhj 728 18 severe severe JJ cord-005646-xhx9pzhj 728 19 , , , cord-005646-xhx9pzhj 728 20 the the DT cord-005646-xhx9pzhj 728 21 abdominal abdominal JJ cord-005646-xhx9pzhj 728 22 distention distention NN cord-005646-xhx9pzhj 728 23 was be VBD cord-005646-xhx9pzhj 728 24 light light JJ cord-005646-xhx9pzhj 728 25 and and CC cord-005646-xhx9pzhj 728 26 disappears disappear VBZ cord-005646-xhx9pzhj 728 27 gradually gradually RB cord-005646-xhx9pzhj 728 28 , , , cord-005646-xhx9pzhj 728 29 the the DT cord-005646-xhx9pzhj 728 30 inflammatory inflammatory JJ cord-005646-xhx9pzhj 728 31 reaction reaction NN cord-005646-xhx9pzhj 728 32 of of IN cord-005646-xhx9pzhj 728 33 the the DT cord-005646-xhx9pzhj 728 34 peritoneal peritoneal JJ cord-005646-xhx9pzhj 728 35 fluid fluid NN cord-005646-xhx9pzhj 728 36 was be VBD cord-005646-xhx9pzhj 728 37 not not RB cord-005646-xhx9pzhj 728 38 so so RB cord-005646-xhx9pzhj 728 39 characteristic characteristic JJ cord-005646-xhx9pzhj 728 40 . . . cord-005646-xhx9pzhj 729 1 CONCLUSION CONCLUSION NNP cord-005646-xhx9pzhj 729 2 ( ( -LRB- cord-005646-xhx9pzhj 729 3 INO INO NNP cord-005646-xhx9pzhj 729 4 ) ) -RRB- cord-005646-xhx9pzhj 729 5 is be VBZ cord-005646-xhx9pzhj 729 6 a a DT cord-005646-xhx9pzhj 729 7 selective selective JJ cord-005646-xhx9pzhj 729 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 729 9 vesodilator vesodilator NN cord-005646-xhx9pzhj 729 10 that that WDT cord-005646-xhx9pzhj 729 11 is be VBZ cord-005646-xhx9pzhj 729 12 rapidly rapidly RB cord-005646-xhx9pzhj 729 13 inactivated inactivate VBN cord-005646-xhx9pzhj 729 14 compared compare VBN cord-005646-xhx9pzhj 729 15 to to IN cord-005646-xhx9pzhj 729 16 intravenous intravenous JJ cord-005646-xhx9pzhj 729 17 vasodilators vasodilator NNS cord-005646-xhx9pzhj 729 18 . . . cord-005646-xhx9pzhj 730 1 These these DT cord-005646-xhx9pzhj 730 2 qualities quality NNS cord-005646-xhx9pzhj 730 3 make make VBP cord-005646-xhx9pzhj 730 4 INO INO NNP cord-005646-xhx9pzhj 730 5 an an DT cord-005646-xhx9pzhj 730 6 attractive attractive JJ cord-005646-xhx9pzhj 730 7 agent agent NN cord-005646-xhx9pzhj 730 8 for for IN cord-005646-xhx9pzhj 730 9 the the DT cord-005646-xhx9pzhj 730 10 treatment treatment NN cord-005646-xhx9pzhj 730 11 of of IN cord-005646-xhx9pzhj 730 12 pulmonary pulmonary JJ cord-005646-xhx9pzhj 730 13 hypertension hypertension NN cord-005646-xhx9pzhj 730 14 ( ( -LRB- cord-005646-xhx9pzhj 730 15 PItTN PItTN NNP cord-005646-xhx9pzhj 730 16 ) ) -RRB- cord-005646-xhx9pzhj 730 17 . . . cord-005646-xhx9pzhj 731 1 The the DT cord-005646-xhx9pzhj 731 2 efficacy efficacy NN cord-005646-xhx9pzhj 731 3 of of IN cord-005646-xhx9pzhj 731 4 INO INO NNP cord-005646-xhx9pzhj 731 5 has have VBZ cord-005646-xhx9pzhj 731 6 been be VBN cord-005646-xhx9pzhj 731 7 studied study VBN cord-005646-xhx9pzhj 731 8 in in IN cord-005646-xhx9pzhj 731 9 persistent persistent JJ cord-005646-xhx9pzhj 731 10 fetal fetal JJ cord-005646-xhx9pzhj 731 11 circulation circulation NN cord-005646-xhx9pzhj 731 12 , , , cord-005646-xhx9pzhj 731 13 acute acute JJ cord-005646-xhx9pzhj 731 14 respiratory respiratory JJ cord-005646-xhx9pzhj 731 15 distress distress NN cord-005646-xhx9pzhj 731 16 syndrome syndrome NN cord-005646-xhx9pzhj 731 17 ( ( -LRB- cord-005646-xhx9pzhj 731 18 ARDS ARDS NNP cord-005646-xhx9pzhj 731 19 ) ) -RRB- cord-005646-xhx9pzhj 731 20 , , , cord-005646-xhx9pzhj 731 21 and and CC cord-005646-xhx9pzhj 731 22 congenital congenital JJ cord-005646-xhx9pzhj 731 23 heart heart NN cord-005646-xhx9pzhj 731 24 disease disease NN cord-005646-xhx9pzhj 731 25 ( ( -LRB- cord-005646-xhx9pzhj 731 26 CHD CHD NNP cord-005646-xhx9pzhj 731 27 ) ) -RRB- cord-005646-xhx9pzhj 731 28 . . . cord-005646-xhx9pzhj 732 1 Potential potential JJ cord-005646-xhx9pzhj 732 2 adverse adverse JJ cord-005646-xhx9pzhj 732 3 effects effect NNS cord-005646-xhx9pzhj 732 4 oflNO oflNO JJS cord-005646-xhx9pzhj 732 5 include include VBP cord-005646-xhx9pzhj 732 6 : : : cord-005646-xhx9pzhj 732 7 nitrogen nitrogen NN cord-005646-xhx9pzhj 732 8 dioxide dioxide NN cord-005646-xhx9pzhj 732 9 ( ( -LRB- cord-005646-xhx9pzhj 732 10 NO0 NO0 NNP cord-005646-xhx9pzhj 732 11 toxicity toxicity NN cord-005646-xhx9pzhj 732 12 , , , cord-005646-xhx9pzhj 732 13 methemoglobinemia methemoglobinemia NN cord-005646-xhx9pzhj 732 14 , , , cord-005646-xhx9pzhj 732 15 and and CC cord-005646-xhx9pzhj 732 16 platelet platelet NN cord-005646-xhx9pzhj 732 17 dysfimction dysfimction NN cord-005646-xhx9pzhj 732 18 . . . cord-005646-xhx9pzhj 733 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 733 2 objective objective NN cord-005646-xhx9pzhj 733 3 was be VBD cord-005646-xhx9pzhj 733 4 to to TO cord-005646-xhx9pzhj 733 5 evaluate evaluate VB cord-005646-xhx9pzhj 733 6 the the DT cord-005646-xhx9pzhj 733 7 safety safety NN cord-005646-xhx9pzhj 733 8 of of IN cord-005646-xhx9pzhj 733 9 INO INO NNP cord-005646-xhx9pzhj 733 10 in in IN cord-005646-xhx9pzhj 733 11 pediatric pediatric JJ cord-005646-xhx9pzhj 733 12 patients patient NNS cord-005646-xhx9pzhj 733 13 ( ( -LRB- cord-005646-xhx9pzhj 733 14 pts pts NNP cord-005646-xhx9pzhj 733 15 ) ) -RRB- cord-005646-xhx9pzhj 733 16 . . . cord-005646-xhx9pzhj 734 1 Methods method NNS cord-005646-xhx9pzhj 734 2 : : : cord-005646-xhx9pzhj 734 3 Pediatric pediatric JJ cord-005646-xhx9pzhj 734 4 pts pt NNS cord-005646-xhx9pzhj 734 5 . . . cord-005646-xhx9pzhj 735 1 with with IN cord-005646-xhx9pzhj 735 2 PHTN PHTN NNP cord-005646-xhx9pzhj 735 3 from from IN cord-005646-xhx9pzhj 735 4 ARDS ARDS NNP cord-005646-xhx9pzhj 735 5 or or CC cord-005646-xhx9pzhj 735 6 CHD CHD NNP cord-005646-xhx9pzhj 735 7 were be VBD cord-005646-xhx9pzhj 735 8 studied study VBN cord-005646-xhx9pzhj 735 9 under under IN cord-005646-xhx9pzhj 735 10 an an DT cord-005646-xhx9pzhj 735 11 established establish VBN cord-005646-xhx9pzhj 735 12 , , , cord-005646-xhx9pzhj 735 13 approved approve VBN cord-005646-xhx9pzhj 735 14 protocol protocol NN cord-005646-xhx9pzhj 735 15 conforming conform VBG cord-005646-xhx9pzhj 735 16 to to IN cord-005646-xhx9pzhj 735 17 FDA FDA NNP cord-005646-xhx9pzhj 735 18 guidelines guideline NNS cord-005646-xhx9pzhj 735 19 tbr tbr NNP cord-005646-xhx9pzhj 735 20 an an DT cord-005646-xhx9pzhj 735 21 investigational investigational JJ cord-005646-xhx9pzhj 735 22 new new JJ cord-005646-xhx9pzhj 735 23 drug drug NN cord-005646-xhx9pzhj 735 24 . . . cord-005646-xhx9pzhj 736 1 Informed informed JJ cord-005646-xhx9pzhj 736 2 consent consent NN cord-005646-xhx9pzhj 736 3 was be VBD cord-005646-xhx9pzhj 736 4 obtained obtain VBN cord-005646-xhx9pzhj 736 5 for for IN cord-005646-xhx9pzhj 736 6 each each DT cord-005646-xhx9pzhj 736 7 child child NN cord-005646-xhx9pzhj 736 8 prior prior RB cord-005646-xhx9pzhj 736 9 to to IN cord-005646-xhx9pzhj 736 10 treatment treatment NN cord-005646-xhx9pzhj 736 11 . . . cord-005646-xhx9pzhj 737 1 1NO 1no CD cord-005646-xhx9pzhj 737 2 was be VBD cord-005646-xhx9pzhj 737 3 sequentially sequentially RB cord-005646-xhx9pzhj 737 4 titratad titratad NN cord-005646-xhx9pzhj 737 5 from from IN cord-005646-xhx9pzhj 737 6 10 10 CD cord-005646-xhx9pzhj 737 7 parts part NNS cord-005646-xhx9pzhj 737 8 per per IN cord-005646-xhx9pzhj 737 9 million million CD cord-005646-xhx9pzhj 737 10 ( ( -LRB- cord-005646-xhx9pzhj 737 11 ppm ppm NN cord-005646-xhx9pzhj 737 12 ) ) -RRB- cord-005646-xhx9pzhj 737 13 to to IN cord-005646-xhx9pzhj 737 14 20 20 CD cord-005646-xhx9pzhj 737 15 , , , cord-005646-xhx9pzhj 737 16 40 40 CD cord-005646-xhx9pzhj 737 17 , , , cord-005646-xhx9pzhj 737 18 60 60 CD cord-005646-xhx9pzhj 737 19 , , , cord-005646-xhx9pzhj 737 20 and and CC cord-005646-xhx9pzhj 737 21 80 80 CD cord-005646-xhx9pzhj 737 22 ppm ppm NN cord-005646-xhx9pzhj 737 23 at at IN cord-005646-xhx9pzhj 737 24 ten ten CD cord-005646-xhx9pzhj 737 25 minute minute NN cord-005646-xhx9pzhj 737 26 intervals interval NNS cord-005646-xhx9pzhj 737 27 . . . cord-005646-xhx9pzhj 738 1 Parameters parameter NNS cord-005646-xhx9pzhj 738 2 monitored monitor VBD cord-005646-xhx9pzhj 738 3 before before RB cord-005646-xhx9pzhj 738 4 and and CC cord-005646-xhx9pzhj 738 5 during during IN cord-005646-xhx9pzhj 738 6 therapy therapy NN cord-005646-xhx9pzhj 738 7 included include VBD cord-005646-xhx9pzhj 738 8 nitric nitric JJ cord-005646-xhx9pzhj 738 9 oxide oxide NN cord-005646-xhx9pzhj 738 10 ( ( -LRB- cord-005646-xhx9pzhj 738 11 NO no UH cord-005646-xhx9pzhj 738 12 ) ) -RRB- cord-005646-xhx9pzhj 738 13 and and CC cord-005646-xhx9pzhj 738 14 NO~ NO~ NNP cord-005646-xhx9pzhj 738 15 concentrations concentration NNS cord-005646-xhx9pzhj 738 16 ( ( -LRB- cord-005646-xhx9pzhj 738 17 cone cone NN cord-005646-xhx9pzhj 738 18 . . . cord-005646-xhx9pzhj 738 19 ) ) -RRB- cord-005646-xhx9pzhj 739 1 , , , cord-005646-xhx9pzhj 739 2 mean mean VB cord-005646-xhx9pzhj 739 3 arterial arterial JJ cord-005646-xhx9pzhj 739 4 blood blood NN cord-005646-xhx9pzhj 739 5 pressure pressure NN cord-005646-xhx9pzhj 739 6 ( ( -LRB- cord-005646-xhx9pzhj 739 7 MAP MAP NNP cord-005646-xhx9pzhj 739 8 ) ) -RRB- cord-005646-xhx9pzhj 739 9 , , , cord-005646-xhx9pzhj 739 10 and and CC cord-005646-xhx9pzhj 739 11 percent percent NN cord-005646-xhx9pzhj 739 12 methemoglobin methemoglobin NNP cord-005646-xhx9pzhj 739 13 ( ( -LRB- cord-005646-xhx9pzhj 739 14 MHG MHG NNP cord-005646-xhx9pzhj 739 15 ) ) -RRB- cord-005646-xhx9pzhj 739 16 . . . cord-005646-xhx9pzhj 740 1 NO no UH cord-005646-xhx9pzhj 740 2 and and CC cord-005646-xhx9pzhj 740 3 NOz noz JJ cord-005646-xhx9pzhj 740 4 levels level NNS cord-005646-xhx9pzhj 740 5 were be VBD cord-005646-xhx9pzhj 740 6 continuously continuously RB cord-005646-xhx9pzhj 740 7 monitored monitor VBN cord-005646-xhx9pzhj 740 8 using use VBG cord-005646-xhx9pzhj 740 9 an an DT cord-005646-xhx9pzhj 740 10 inline inline JJ cord-005646-xhx9pzhj 740 11 Dr Dr NNP cord-005646-xhx9pzhj 740 12 ~ ~ NNP cord-005646-xhx9pzhj 740 13 ger ger NNP cord-005646-xhx9pzhj 740 14 electrochemical electrochemical JJ cord-005646-xhx9pzhj 740 15 detection detection NN cord-005646-xhx9pzhj 740 16 device device NN cord-005646-xhx9pzhj 740 17 . . . cord-005646-xhx9pzhj 741 1 ~,Litp ~,Litp NNP cord-005646-xhx9pzhj 741 2 was be VBD cord-005646-xhx9pzhj 741 3 continuously continuously RB cord-005646-xhx9pzhj 741 4 measured measure VBN cord-005646-xhx9pzhj 741 5 with with IN cord-005646-xhx9pzhj 741 6 an an DT cord-005646-xhx9pzhj 741 7 indwelling indwell VBG cord-005646-xhx9pzhj 741 8 arterial arterial JJ cord-005646-xhx9pzhj 741 9 catheter catheter NN cord-005646-xhx9pzhj 741 10 . . . cord-005646-xhx9pzhj 742 1 MHG MHG NNP cord-005646-xhx9pzhj 742 2 was be VBD cord-005646-xhx9pzhj 742 3 measured measure VBN cord-005646-xhx9pzhj 742 4 by by IN cord-005646-xhx9pzhj 742 5 co co NN cord-005646-xhx9pzhj 742 6 - - NN cord-005646-xhx9pzhj 742 7 oximetry oximetry NN cord-005646-xhx9pzhj 742 8 . . . cord-005646-xhx9pzhj 743 1 A a DT cord-005646-xhx9pzhj 743 2 MHG MHG NNP cord-005646-xhx9pzhj 743 3 level level NN cord-005646-xhx9pzhj 743 4 e e NN cord-005646-xhx9pzhj 743 5 5 5 CD cord-005646-xhx9pzhj 743 6 % % NN cord-005646-xhx9pzhj 743 7 or or CC cord-005646-xhx9pzhj 743 8 NO2 NO2 NNP cord-005646-xhx9pzhj 743 9 cone cone NN cord-005646-xhx9pzhj 743 10 . . . cord-005646-xhx9pzhj 744 1 ~ ~ NFP cord-005646-xhx9pzhj 744 2 5 5 CD cord-005646-xhx9pzhj 744 3 ppm ppm NN cord-005646-xhx9pzhj 744 4 were be VBD cord-005646-xhx9pzhj 744 5 considered consider VBN cord-005646-xhx9pzhj 744 6 adverse adverse JJ cord-005646-xhx9pzhj 744 7 effects effect NNS cord-005646-xhx9pzhj 744 8 by by IN cord-005646-xhx9pzhj 744 9 study study NN cord-005646-xhx9pzhj 744 10 criteria criterion NNS cord-005646-xhx9pzhj 744 11 . . . cord-005646-xhx9pzhj 745 1 Pretreatment pretreatment NN cord-005646-xhx9pzhj 745 2 MAP MAP NNP cord-005646-xhx9pzhj 745 3 was be VBD cord-005646-xhx9pzhj 745 4 compared compare VBN cord-005646-xhx9pzhj 745 5 to to IN cord-005646-xhx9pzhj 745 6 MAP MAP NNP cord-005646-xhx9pzhj 745 7 at at IN cord-005646-xhx9pzhj 745 8 40 40 CD cord-005646-xhx9pzhj 745 9 and and CC cord-005646-xhx9pzhj 745 10 80 80 CD cord-005646-xhx9pzhj 745 11 ppm ppm NN cord-005646-xhx9pzhj 746 1 INO INO NNP cord-005646-xhx9pzhj 746 2 using use VBG cord-005646-xhx9pzhj 746 3 paired pair VBN cord-005646-xhx9pzhj 746 4 t t NN cord-005646-xhx9pzhj 746 5 - - HYPH cord-005646-xhx9pzhj 746 6 tests test NNS cord-005646-xhx9pzhj 746 7 . . . cord-005646-xhx9pzhj 747 1 Ap Ap NNP cord-005646-xhx9pzhj 747 2 value value NN cord-005646-xhx9pzhj 747 3 < < XX cord-005646-xhx9pzhj 747 4 0.05 0.05 CD cord-005646-xhx9pzhj 747 5 was be VBD cord-005646-xhx9pzhj 747 6 considered consider VBN cord-005646-xhx9pzhj 747 7 statistically statistically RB cord-005646-xhx9pzhj 747 8 significant significant JJ cord-005646-xhx9pzhj 747 9 . . . cord-005646-xhx9pzhj 748 1 Results result NNS cord-005646-xhx9pzhj 748 2 : : : cord-005646-xhx9pzhj 749 1 Thirty thirty CD cord-005646-xhx9pzhj 749 2 - - HYPH cord-005646-xhx9pzhj 749 3 two two CD cord-005646-xhx9pzhj 749 4 mechanically mechanically RB cord-005646-xhx9pzhj 749 5 ventilated ventilate VBD cord-005646-xhx9pzhj 749 6 children child NNS cord-005646-xhx9pzhj 749 7 with with IN cord-005646-xhx9pzhj 749 8 PHTN PHTN NNP cord-005646-xhx9pzhj 750 1 ( ( -LRB- cord-005646-xhx9pzhj 750 2 16 16 CD cord-005646-xhx9pzhj 750 3 with with IN cord-005646-xhx9pzhj 750 4 ARDS ARDS NNP cord-005646-xhx9pzhj 750 5 , , , cord-005646-xhx9pzhj 750 6 16 16 CD cord-005646-xhx9pzhj 750 7 with with IN cord-005646-xhx9pzhj 750 8 CHD CHD NNP cord-005646-xhx9pzhj 750 9 ) ) -RRB- cord-005646-xhx9pzhj 750 10 were be VBD cord-005646-xhx9pzhj 750 11 studied study VBN cord-005646-xhx9pzhj 750 12 . . . cord-005646-xhx9pzhj 751 1 Five five CD cord-005646-xhx9pzhj 751 2 pts pt NNS cord-005646-xhx9pzhj 751 3 . . . cord-005646-xhx9pzhj 751 4 were be VBD cord-005646-xhx9pzhj 751 5 treated treat VBN cord-005646-xhx9pzhj 751 6 following follow VBG cord-005646-xhx9pzhj 751 7 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 751 8 bypass bypass NN cord-005646-xhx9pzhj 751 9 . . . cord-005646-xhx9pzhj 752 1 Methemoglobin Methemoglobin NNP cord-005646-xhx9pzhj 753 1 ( ( -LRB- cord-005646-xhx9pzhj 753 2 Met Met NNP cord-005646-xhx9pzhj 753 3 - - HYPH cord-005646-xhx9pzhj 753 4 Hb Hb NNP cord-005646-xhx9pzhj 753 5 ) ) -RRB- cord-005646-xhx9pzhj 753 6 levels level NNS cord-005646-xhx9pzhj 753 7 were be VBD cord-005646-xhx9pzhj 753 8 routinely routinely RB cord-005646-xhx9pzhj 753 9 measured measure VBN cord-005646-xhx9pzhj 753 10 in in IN cord-005646-xhx9pzhj 753 11 two two CD cord-005646-xhx9pzhj 753 12 prospective prospective JJ cord-005646-xhx9pzhj 753 13 clinical clinical JJ cord-005646-xhx9pzhj 753 14 studies study NNS cord-005646-xhx9pzhj 753 15 on on IN cord-005646-xhx9pzhj 753 16 NO no DT cord-005646-xhx9pzhj 753 17 inhalation inhalation NN cord-005646-xhx9pzhj 753 18 in in IN cord-005646-xhx9pzhj 753 19 25 25 CD cord-005646-xhx9pzhj 753 20 pediatric pediatric JJ cord-005646-xhx9pzhj 753 21 patients patient NNS cord-005646-xhx9pzhj 753 22 with with IN cord-005646-xhx9pzhj 753 23 pulmonary pulmonary JJ cord-005646-xhx9pzhj 753 24 hypertension hypertension NN cord-005646-xhx9pzhj 753 25 following follow VBG cord-005646-xhx9pzhj 753 26 heart heart NN cord-005646-xhx9pzhj 753 27 surgery surgery NN cord-005646-xhx9pzhj 753 28 with with IN cord-005646-xhx9pzhj 753 29 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 753 30 circulation circulation NN cord-005646-xhx9pzhj 753 31 and and CC cord-005646-xhx9pzhj 753 32 in in IN cord-005646-xhx9pzhj 753 33 19 19 CD cord-005646-xhx9pzhj 753 34 pediatric pediatric JJ cord-005646-xhx9pzhj 753 35 and and CC cord-005646-xhx9pzhj 753 36 neonatal neonatal JJ cord-005646-xhx9pzhj 753 37 ARDS ARDS NNP cord-005646-xhx9pzhj 753 38 patients patient NNS cord-005646-xhx9pzhj 753 39 , , , cord-005646-xhx9pzhj 753 40 The the DT cord-005646-xhx9pzhj 753 41 observed observed JJ cord-005646-xhx9pzhj 753 42 differences difference NNS cord-005646-xhx9pzhj 753 43 between between IN cord-005646-xhx9pzhj 753 44 the the DT cord-005646-xhx9pzhj 753 45 groups group NNS cord-005646-xhx9pzhj 753 46 prompted prompt VBN cord-005646-xhx9pzhj 753 47 in in IN cord-005646-xhx9pzhj 753 48 an an DT cord-005646-xhx9pzhj 753 49 in in FW cord-005646-xhx9pzhj 753 50 vitro vitro FW cord-005646-xhx9pzhj 753 51 study study NN cord-005646-xhx9pzhj 753 52 , , , cord-005646-xhx9pzhj 753 53 Red red JJ cord-005646-xhx9pzhj 753 54 blood blood NN cord-005646-xhx9pzhj 753 55 cells cell NNS cord-005646-xhx9pzhj 753 56 ( ( -LRB- cord-005646-xhx9pzhj 753 57 RBC RBC NNP cord-005646-xhx9pzhj 753 58 ) ) -RRB- cord-005646-xhx9pzhj 753 59 of of IN cord-005646-xhx9pzhj 753 60 20 20 CD cord-005646-xhx9pzhj 753 61 patients patient NNS cord-005646-xhx9pzhj 753 62 sampled sample VBN cord-005646-xhx9pzhj 753 63 before before IN cord-005646-xhx9pzhj 753 64 and and CC cord-005646-xhx9pzhj 753 65 after after IN cord-005646-xhx9pzhj 753 66 surgery surgery NN cord-005646-xhx9pzhj 753 67 with with IN cord-005646-xhx9pzhj 753 68 and and CC cord-005646-xhx9pzhj 753 69 without without IN cord-005646-xhx9pzhj 753 70 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 753 71 circulation circulation NN cord-005646-xhx9pzhj 753 72 ( ( -LRB- cord-005646-xhx9pzhj 753 73 ECC ECC NNP cord-005646-xhx9pzhj 753 74 ) ) -RRB- cord-005646-xhx9pzhj 753 75 , , , cord-005646-xhx9pzhj 753 76 respectively respectively RB cord-005646-xhx9pzhj 753 77 , , , cord-005646-xhx9pzhj 753 78 were be VBD cord-005646-xhx9pzhj 753 79 incubated incubate VBN cord-005646-xhx9pzhj 753 80 with with IN cord-005646-xhx9pzhj 753 81 32 32 CD cord-005646-xhx9pzhj 753 82 ppm ppm NN cord-005646-xhx9pzhj 753 83 NO no NN cord-005646-xhx9pzhj 753 84 for for IN cord-005646-xhx9pzhj 753 85 100 100 CD cord-005646-xhx9pzhj 753 86 rain rain NN cord-005646-xhx9pzhj 753 87 , , , cord-005646-xhx9pzhj 753 88 Met Met NNP cord-005646-xhx9pzhj 753 89 - - HYPH cord-005646-xhx9pzhj 753 90 Hb Hb NNP cord-005646-xhx9pzhj 753 91 , , , cord-005646-xhx9pzhj 753 92 ATP ATP NNP cord-005646-xhx9pzhj 753 93 , , , cord-005646-xhx9pzhj 753 94 and and CC cord-005646-xhx9pzhj 753 95 NADHt NADHt NNPS cord-005646-xhx9pzhj 753 96 NADPH NADPH NNP cord-005646-xhx9pzhj 753 97 concentrations concentration NNS cord-005646-xhx9pzhj 753 98 were be VBD cord-005646-xhx9pzhj 753 99 compared compare VBN cord-005646-xhx9pzhj 753 100 , , , cord-005646-xhx9pzhj 754 1 During during IN cord-005646-xhx9pzhj 754 2 therapeutic therapeutic JJ cord-005646-xhx9pzhj 754 3 exposure exposure NN cord-005646-xhx9pzhj 754 4 NO no RB cord-005646-xhx9pzhj 754 5 increased increase VBN cord-005646-xhx9pzhj 754 6 Met Met NNP cord-005646-xhx9pzhj 754 7 - - HYPH cord-005646-xhx9pzhj 754 8 Hb Hb NNP cord-005646-xhx9pzhj 754 9 from from IN cord-005646-xhx9pzhj 754 10 0.2 0.2 CD cord-005646-xhx9pzhj 755 1 -2- -2- : cord-005646-xhx9pzhj 755 2 _ _ NN cord-005646-xhx9pzhj 755 3 0.1 0.1 CD cord-005646-xhx9pzhj 755 4 to to IN cord-005646-xhx9pzhj 755 5 1.2 1.2 CD cord-005646-xhx9pzhj 755 6 _ _ NN cord-005646-xhx9pzhj 755 7 + + CC cord-005646-xhx9pzhj 756 1 0.7 0.7 CD cord-005646-xhx9pzhj 756 2 % % NN cord-005646-xhx9pzhj 756 3 in in IN cord-005646-xhx9pzhj 756 4 cardiac cardiac JJ cord-005646-xhx9pzhj 756 5 surgery surgery NN cord-005646-xhx9pzhj 756 6 patients patient NNS cord-005646-xhx9pzhj 756 7 and and CC cord-005646-xhx9pzhj 756 8 from from IN cord-005646-xhx9pzhj 756 9 0.2 0.2 CD cord-005646-xhx9pzhj 756 10 ± ± CD cord-005646-xhx9pzhj 756 11 0,1 0,1 CD cord-005646-xhx9pzhj 756 12 to to IN cord-005646-xhx9pzhj 756 13 0.5 0.5 CD cord-005646-xhx9pzhj 756 14 ± ± CD cord-005646-xhx9pzhj 756 15 0.4 0.4 CD cord-005646-xhx9pzhj 756 16 % % NN cord-005646-xhx9pzhj 756 17 in in IN cord-005646-xhx9pzhj 756 18 ARDS ARDS NNP cord-005646-xhx9pzhj 756 19 patients patient NNS cord-005646-xhx9pzhj 756 20 ( ( -LRB- cord-005646-xhx9pzhj 756 21 p p XX cord-005646-xhx9pzhj 756 22 < < XX cord-005646-xhx9pzhj 756 23 0.01 0.01 CD cord-005646-xhx9pzhj 756 24 ) ) -RRB- cord-005646-xhx9pzhj 756 25 . . . cord-005646-xhx9pzhj 757 1 RBC RBC NNP cord-005646-xhx9pzhj 757 2 's 's POS cord-005646-xhx9pzhj 757 3 having have VBG cord-005646-xhx9pzhj 757 4 undergone undergo VBN cord-005646-xhx9pzhj 757 5 ECC ECC NNP cord-005646-xhx9pzhj 757 6 were be VBD cord-005646-xhx9pzhj 757 7 more more RBR cord-005646-xhx9pzhj 757 8 susceptible susceptible JJ cord-005646-xhx9pzhj 757 9 to to IN cord-005646-xhx9pzhj 757 10 Met Met NNP cord-005646-xhx9pzhj 757 11 - - HYPH cord-005646-xhx9pzhj 757 12 Hb Hb NNP cord-005646-xhx9pzhj 757 13 formation formation NN cord-005646-xhx9pzhj 758 1 ( ( -LRB- cord-005646-xhx9pzhj 758 2 p p NN cord-005646-xhx9pzhj 758 3 < < XX cord-005646-xhx9pzhj 758 4 0,001 0,001 CD cord-005646-xhx9pzhj 758 5 ) ) -RRB- cord-005646-xhx9pzhj 759 1 whereas whereas IN cord-005646-xhx9pzhj 759 2 intracellular intracellular JJ cord-005646-xhx9pzhj 759 3 coenzymes coenzyme NNS cord-005646-xhx9pzhj 759 4 did do VBD cord-005646-xhx9pzhj 759 5 not not RB cord-005646-xhx9pzhj 759 6 differ differ VB cord-005646-xhx9pzhj 759 7 neither neither CC cord-005646-xhx9pzhj 759 8 between between IN cord-005646-xhx9pzhj 759 9 the the DT cord-005646-xhx9pzhj 759 10 groups group NNS cord-005646-xhx9pzhj 759 11 ( ( -LRB- cord-005646-xhx9pzhj 759 12 table table NN cord-005646-xhx9pzhj 759 13 ) ) -RRB- cord-005646-xhx9pzhj 759 14 nor nor CC cord-005646-xhx9pzhj 759 15 before before IN cord-005646-xhx9pzhj 759 16 and and CC cord-005646-xhx9pzhj 759 17 after after IN cord-005646-xhx9pzhj 759 18 NO no DT cord-005646-xhx9pzhj 759 19 exposure exposure NN cord-005646-xhx9pzhj 759 20 . . . cord-005646-xhx9pzhj 760 1 ECC ECC NNP cord-005646-xhx9pzhj 760 2 predisposes predispose VBZ cord-005646-xhx9pzhj 760 3 to to IN cord-005646-xhx9pzhj 760 4 increased increase VBN cord-005646-xhx9pzhj 760 5 methemoglobinemia methemoglobinemia NN cord-005646-xhx9pzhj 760 6 upon upon IN cord-005646-xhx9pzhj 760 7 exposure exposure NN cord-005646-xhx9pzhj 760 8 to to IN cord-005646-xhx9pzhj 760 9 NO no NN cord-005646-xhx9pzhj 760 10 both both DT cord-005646-xhx9pzhj 760 11 in in IN cord-005646-xhx9pzhj 760 12 vivo vivo NN cord-005646-xhx9pzhj 760 13 and and CC cord-005646-xhx9pzhj 760 14 in in IN cord-005646-xhx9pzhj 760 15 vitro vitro FW cord-005646-xhx9pzhj 760 16 . . . cord-005646-xhx9pzhj 761 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 761 2 data datum NNS cord-005646-xhx9pzhj 761 3 suggest suggest VBP cord-005646-xhx9pzhj 761 4 a a DT cord-005646-xhx9pzhj 761 5 reduced reduce VBN cord-005646-xhx9pzhj 761 6 activity activity NN cord-005646-xhx9pzhj 761 7 of of IN cord-005646-xhx9pzhj 761 8 Met Met NNP cord-005646-xhx9pzhj 761 9 - - HYPH cord-005646-xhx9pzhj 761 10 Hb Hb NNP cord-005646-xhx9pzhj 761 11 reducing reduce VBG cord-005646-xhx9pzhj 761 12 enzymes enzyme NNS cord-005646-xhx9pzhj 761 13 rather rather RB cord-005646-xhx9pzhj 761 14 than than IN cord-005646-xhx9pzhj 761 15 diminished diminished JJ cord-005646-xhx9pzhj 761 16 availability availability NN cord-005646-xhx9pzhj 761 17 of of IN cord-005646-xhx9pzhj 761 18 energetic energetic JJ cord-005646-xhx9pzhj 761 19 substrates substrate NNS cord-005646-xhx9pzhj 761 20 , , , cord-005646-xhx9pzhj 761 21 Variation variation NN cord-005646-xhx9pzhj 761 22 of of IN cord-005646-xhx9pzhj 761 23 the the DT cord-005646-xhx9pzhj 761 24 inhaled inhale VBN cord-005646-xhx9pzhj 761 25 nitric nitric JJ cord-005646-xhx9pzhj 761 26 oxide oxide NN cord-005646-xhx9pzhj 761 27 concentration concentration NN cord-005646-xhx9pzhj 761 28 with with IN cord-005646-xhx9pzhj 761 29 the the DT cord-005646-xhx9pzhj 761 30 use use NN cord-005646-xhx9pzhj 761 31 of of IN cord-005646-xhx9pzhj 761 32 a a DT cord-005646-xhx9pzhj 761 33 continuous continuous JJ cord-005646-xhx9pzhj 761 34 flow flow NN cord-005646-xhx9pzhj 761 35 ventilator ventilator NN cord-005646-xhx9pzhj 761 36 . . . cord-005646-xhx9pzhj 762 1 Anne Anne NNP cord-005646-xhx9pzhj 762 2 PMC PMC NNP cord-005646-xhx9pzhj 762 3 De De NNP cord-005646-xhx9pzhj 762 4 Jaegere Jaegere NNP cord-005646-xhx9pzhj 762 5 ~ ~ NFP cord-005646-xhx9pzhj 763 1 , , , cord-005646-xhx9pzhj 763 2 Frans Frans NNP cord-005646-xhx9pzhj 763 3 IM IM NNP cord-005646-xhx9pzhj 763 4 Jacobs Jacobs NNP cord-005646-xhx9pzhj 763 5 2 2 CD cord-005646-xhx9pzhj 763 6 , , , cord-005646-xhx9pzhj 763 7 Nico Nico NNP cord-005646-xhx9pzhj 763 8 GC GC NNP cord-005646-xhx9pzhj 763 9 Laheij Laheij NNP cord-005646-xhx9pzhj 763 10 2 2 CD cord-005646-xhx9pzhj 763 11 , , , cord-005646-xhx9pzhj 763 12 John John NNP cord-005646-xhx9pzhj 763 13 N N NNP cord-005646-xhx9pzhj 763 14 van van NNP cord-005646-xhx9pzhj 763 15 den den NNP cord-005646-xhx9pzhj 763 16 Anker Anker NNP cord-005646-xhx9pzhj 763 17 t t NN cord-005646-xhx9pzhj 763 18 . . . cord-005646-xhx9pzhj 764 1 Dept Dept NNP cord-005646-xhx9pzhj 764 2 . . . cord-005646-xhx9pzhj 765 1 of of IN cord-005646-xhx9pzhj 765 2 Paediatrics Paediatrics NNP cord-005646-xhx9pzhj 765 3 ~ ~ NFP cord-005646-xhx9pzhj 765 4 , , , cord-005646-xhx9pzhj 765 5 Central central JJ cord-005646-xhx9pzhj 765 6 instrumentation instrumentation NN cord-005646-xhx9pzhj 765 7 2 2 CD cord-005646-xhx9pzhj 765 8 , , , cord-005646-xhx9pzhj 765 9 Sophia Sophia NNP cord-005646-xhx9pzhj 765 10 Children Children NNP cord-005646-xhx9pzhj 765 11 's 's POS cord-005646-xhx9pzhj 765 12 Hospital Hospital NNP cord-005646-xhx9pzhj 765 13 , , , cord-005646-xhx9pzhj 766 1 Erasmus Erasmus NNP cord-005646-xhx9pzhj 766 2 University University NNP cord-005646-xhx9pzhj 766 3 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 766 4 , , , cord-005646-xhx9pzhj 766 5 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 766 6 , , , cord-005646-xhx9pzhj 766 7 the the DT cord-005646-xhx9pzhj 766 8 Netherlands Netherlands NNP cord-005646-xhx9pzhj 766 9 . . . cord-005646-xhx9pzhj 767 1 Objective objective NN cord-005646-xhx9pzhj 767 2 : : : cord-005646-xhx9pzhj 767 3 To to TO cord-005646-xhx9pzhj 767 4 investigate investigate VB cord-005646-xhx9pzhj 767 5 the the DT cord-005646-xhx9pzhj 767 6 homogeneity homogeneity NN cord-005646-xhx9pzhj 767 7 of of IN cord-005646-xhx9pzhj 767 8 nitric nitric NN cord-005646-xhx9pzhj 767 9 oxide oxide NN cord-005646-xhx9pzhj 767 10 ( ( -LRB- cord-005646-xhx9pzhj 767 11 NO no UH cord-005646-xhx9pzhj 767 12 ) ) -RRB- cord-005646-xhx9pzhj 767 13 concentration concentration NN cord-005646-xhx9pzhj 767 14 in in IN cord-005646-xhx9pzhj 767 15 a a DT cord-005646-xhx9pzhj 767 16 delivery delivery NN cord-005646-xhx9pzhj 767 17 system system NN cord-005646-xhx9pzhj 767 18 with with IN cord-005646-xhx9pzhj 767 19 a a DT cord-005646-xhx9pzhj 767 20 continuous continuous JJ cord-005646-xhx9pzhj 767 21 flow flow NN cord-005646-xhx9pzhj 767 22 ventilator ventilator NN cord-005646-xhx9pzhj 767 23 . . . cord-005646-xhx9pzhj 768 1 Design design NN cord-005646-xhx9pzhj 768 2 : : : cord-005646-xhx9pzhj 769 1 Bench bench NN cord-005646-xhx9pzhj 769 2 study study NN cord-005646-xhx9pzhj 769 3 , , , cord-005646-xhx9pzhj 769 4 Setting setting NN cord-005646-xhx9pzhj 769 5 : : : cord-005646-xhx9pzhj 770 1 Biomedical biomedical JJ cord-005646-xhx9pzhj 770 2 laboratory laboratory NN cord-005646-xhx9pzhj 770 3 . . . cord-005646-xhx9pzhj 771 1 Interventions intervention NNS cord-005646-xhx9pzhj 771 2 : : : cord-005646-xhx9pzhj 772 1 A a DT cord-005646-xhx9pzhj 772 2 nitrogen nitrogen NN cord-005646-xhx9pzhj 772 3 / / SYM cord-005646-xhx9pzhj 772 4 nitric nitric NN cord-005646-xhx9pzhj 772 5 oxide oxide NN cord-005646-xhx9pzhj 772 6 ( ( -LRB- cord-005646-xhx9pzhj 772 7 NJNO NJNO NNP cord-005646-xhx9pzhj 772 8 ) ) -RRB- cord-005646-xhx9pzhj 772 9 gas gas NN cord-005646-xhx9pzhj 772 10 mixture mixture NN cord-005646-xhx9pzhj 772 11 was be VBD cord-005646-xhx9pzhj 772 12 injected inject VBN cord-005646-xhx9pzhj 772 13 at at IN cord-005646-xhx9pzhj 772 14 three three CD cord-005646-xhx9pzhj 772 15 different different JJ cord-005646-xhx9pzhj 772 16 sites site NNS cord-005646-xhx9pzhj 772 17 in in IN cord-005646-xhx9pzhj 772 18 the the DT cord-005646-xhx9pzhj 772 19 patient patient NN cord-005646-xhx9pzhj 772 20 circuit circuit NN cord-005646-xhx9pzhj 772 21 : : : cord-005646-xhx9pzhj 772 22 just just RB cord-005646-xhx9pzhj 772 23 before before RB cord-005646-xhx9pzhj 772 24 and and CC cord-005646-xhx9pzhj 772 25 just just RB cord-005646-xhx9pzhj 772 26 behind behind IN cord-005646-xhx9pzhj 772 27 the the DT cord-005646-xhx9pzhj 772 28 humidifier humidifier NN cord-005646-xhx9pzhj 772 29 , , , cord-005646-xhx9pzhj 772 30 and and CC cord-005646-xhx9pzhj 772 31 20 20 CD cord-005646-xhx9pzhj 772 32 centimetres centimetre NNS cord-005646-xhx9pzhj 772 33 before before IN cord-005646-xhx9pzhj 772 34 the the DT cord-005646-xhx9pzhj 772 35 Y Y NNP cord-005646-xhx9pzhj 772 36 - - HYPH cord-005646-xhx9pzhj 772 37 connector connector NN cord-005646-xhx9pzhj 772 38 . . . cord-005646-xhx9pzhj 773 1 Ventilator Ventilator NNP cord-005646-xhx9pzhj 773 2 flow flow NN cord-005646-xhx9pzhj 773 3 ( ( -LRB- cord-005646-xhx9pzhj 773 4 12 12 CD cord-005646-xhx9pzhj 773 5 , , , cord-005646-xhx9pzhj 773 6 15 15 CD cord-005646-xhx9pzhj 773 7 , , , cord-005646-xhx9pzhj 773 8 20 20 CD cord-005646-xhx9pzhj 773 9 L l NN cord-005646-xhx9pzhj 773 10 / / SYM cord-005646-xhx9pzhj 773 11 rain rain NN cord-005646-xhx9pzhj 773 12 ) ) -RRB- cord-005646-xhx9pzhj 773 13 , , , cord-005646-xhx9pzhj 773 14 ventilator ventilator NN cord-005646-xhx9pzhj 773 15 rate rate NN cord-005646-xhx9pzhj 773 16 ( ( -LRB- cord-005646-xhx9pzhj 773 17 40 40 CD cord-005646-xhx9pzhj 773 18 to to TO cord-005646-xhx9pzhj 773 19 110 110 CD cord-005646-xhx9pzhj 773 20 , , , cord-005646-xhx9pzhj 773 21 increments increment NNS cord-005646-xhx9pzhj 773 22 of of IN cord-005646-xhx9pzhj 773 23 10 10 CD cord-005646-xhx9pzhj 773 24 ) ) -RRB- cord-005646-xhx9pzhj 773 25 and and CC cord-005646-xhx9pzhj 773 26 compliance compliance NN cord-005646-xhx9pzhj 773 27 of of IN cord-005646-xhx9pzhj 773 28 the the DT cord-005646-xhx9pzhj 773 29 testlung testlung NNP cord-005646-xhx9pzhj 773 30 ( ( -LRB- cord-005646-xhx9pzhj 773 31 0.36 0.36 CD cord-005646-xhx9pzhj 773 32 ; ; : cord-005646-xhx9pzhj 773 33 0.5 0.5 CD cord-005646-xhx9pzhj 773 34 ; ; : cord-005646-xhx9pzhj 773 35 1.0 1.0 CD cord-005646-xhx9pzhj 773 36 ml ml NNS cord-005646-xhx9pzhj 773 37 / / SYM cord-005646-xhx9pzhj 773 38 cm cm NNP cord-005646-xhx9pzhj 773 39 H20 H20 NNP cord-005646-xhx9pzhj 773 40 ) ) -RRB- cord-005646-xhx9pzhj 773 41 were be VBD cord-005646-xhx9pzhj 773 42 changed change VBN cord-005646-xhx9pzhj 773 43 . . . cord-005646-xhx9pzhj 774 1 Carbon carbon NN cord-005646-xhx9pzhj 774 2 dioxide dioxide NN cord-005646-xhx9pzhj 774 3 ( ( -LRB- cord-005646-xhx9pzhj 774 4 CO2 CO2 NNP cord-005646-xhx9pzhj 774 5 ) ) -RRB- cord-005646-xhx9pzhj 774 6 instead instead RB cord-005646-xhx9pzhj 774 7 of of IN cord-005646-xhx9pzhj 774 8 N2/ n2/ NN cord-005646-xhx9pzhj 775 1 NO no DT cord-005646-xhx9pzhj 775 2 was be VBD cord-005646-xhx9pzhj 775 3 injected inject VBN cord-005646-xhx9pzhj 775 4 at at IN cord-005646-xhx9pzhj 775 5 the the DT cord-005646-xhx9pzhj 775 6 same same JJ cord-005646-xhx9pzhj 775 7 points point NNS cord-005646-xhx9pzhj 775 8 in in IN cord-005646-xhx9pzhj 775 9 the the DT cord-005646-xhx9pzhj 775 10 circuit circuit NN cord-005646-xhx9pzhj 775 11 . . . cord-005646-xhx9pzhj 776 1 Measurements measurement NNS cord-005646-xhx9pzhj 776 2 and and CC cord-005646-xhx9pzhj 776 3 main main JJ cord-005646-xhx9pzhj 776 4 results result NNS cord-005646-xhx9pzhj 776 5 : : : cord-005646-xhx9pzhj 776 6 A a NN cord-005646-xhx9pzhj 776 7 ) ) -RRB- cord-005646-xhx9pzhj 777 1 Though though IN cord-005646-xhx9pzhj 777 2 the the DT cord-005646-xhx9pzhj 777 3 flow flow NN cord-005646-xhx9pzhj 777 4 ratio ratio NN cord-005646-xhx9pzhj 777 5 of of IN cord-005646-xhx9pzhj 777 6 the the DT cord-005646-xhx9pzhj 777 7 NJNO NJNO NNP cord-005646-xhx9pzhj 777 8 and and CC cord-005646-xhx9pzhj 777 9 the the DT cord-005646-xhx9pzhj 777 10 ventilator ventilator NN cord-005646-xhx9pzhj 777 11 gas gas NN cord-005646-xhx9pzhj 777 12 were be VBD cord-005646-xhx9pzhj 777 13 kept keep VBN cord-005646-xhx9pzhj 777 14 constant constant JJ cord-005646-xhx9pzhj 777 15 , , , cord-005646-xhx9pzhj 777 16 the the DT cord-005646-xhx9pzhj 777 17 NO no JJ cord-005646-xhx9pzhj 777 18 concentration concentration NN cord-005646-xhx9pzhj 777 19 ( ( -LRB- cord-005646-xhx9pzhj 777 20 [ [ -LRB- cord-005646-xhx9pzhj 777 21 NO no NN cord-005646-xhx9pzhj 777 22 ] ] -RRB- cord-005646-xhx9pzhj 777 23 ) ) -RRB- cord-005646-xhx9pzhj 777 24 raised raise VBD cord-005646-xhx9pzhj 777 25 with with IN cord-005646-xhx9pzhj 777 26 increasing increase VBG cord-005646-xhx9pzhj 777 27 ventilator ventilator NN cord-005646-xhx9pzhj 777 28 rates rate NNS cord-005646-xhx9pzhj 777 29 . . . cord-005646-xhx9pzhj 778 1 The the DT cord-005646-xhx9pzhj 778 2 increase increase NN cord-005646-xhx9pzhj 778 3 in in IN cord-005646-xhx9pzhj 778 4 [ [ -LRB- cord-005646-xhx9pzhj 778 5 NO no NN cord-005646-xhx9pzhj 778 6 ] ] -RRB- cord-005646-xhx9pzhj 778 7 was be VBD cord-005646-xhx9pzhj 778 8 up up RB cord-005646-xhx9pzhj 778 9 to to TO cord-005646-xhx9pzhj 778 10 40 40 CD cord-005646-xhx9pzhj 778 11 % % NN cord-005646-xhx9pzhj 778 12 when when WRB cord-005646-xhx9pzhj 778 13 the the DT cord-005646-xhx9pzhj 778 14 N2 N2 NNP cord-005646-xhx9pzhj 778 15 / / SYM cord-005646-xhx9pzhj 778 16 NO no DT cord-005646-xhx9pzhj 778 17 injection injection NN cord-005646-xhx9pzhj 778 18 site site NN cord-005646-xhx9pzhj 778 19 was be VBD cord-005646-xhx9pzhj 778 20 close close JJ cord-005646-xhx9pzhj 778 21 to to IN cord-005646-xhx9pzhj 778 22 the the DT cord-005646-xhx9pzhj 778 23 Y Y NNP cord-005646-xhx9pzhj 778 24 - - HYPH cord-005646-xhx9pzhj 778 25 connector connector NN cord-005646-xhx9pzhj 778 26 of of IN cord-005646-xhx9pzhj 778 27 the the DT cord-005646-xhx9pzhj 778 28 ventilator ventilator NN cord-005646-xhx9pzhj 778 29 circuit circuit NN cord-005646-xhx9pzhj 778 30 . . . cord-005646-xhx9pzhj 779 1 Minimal minimal JJ cord-005646-xhx9pzhj 779 2 changes change NNS cord-005646-xhx9pzhj 779 3 in in IN cord-005646-xhx9pzhj 779 4 [ [ -LRB- cord-005646-xhx9pzhj 779 5 NO no NN cord-005646-xhx9pzhj 779 6 ] ] -RRB- cord-005646-xhx9pzhj 779 7 were be VBD cord-005646-xhx9pzhj 779 8 noticed notice VBN cord-005646-xhx9pzhj 779 9 when when WRB cord-005646-xhx9pzhj 779 10 the the DT cord-005646-xhx9pzhj 779 11 N~/NO N~/NO NNP cord-005646-xhx9pzhj 779 12 was be VBD cord-005646-xhx9pzhj 779 13 mixed mixed JJ cord-005646-xhx9pzhj 779 14 to to IN cord-005646-xhx9pzhj 779 15 the the DT cord-005646-xhx9pzhj 779 16 ventilator ventilator NN cord-005646-xhx9pzhj 779 17 gas gas NN cord-005646-xhx9pzhj 779 18 before before IN cord-005646-xhx9pzhj 779 19 the the DT cord-005646-xhx9pzhj 779 20 humidifier humidifier NN cord-005646-xhx9pzhj 779 21 . . . cord-005646-xhx9pzhj 780 1 B b LS cord-005646-xhx9pzhj 780 2 ) ) -RRB- cord-005646-xhx9pzhj 780 3 Analysis analysis NN cord-005646-xhx9pzhj 780 4 of of IN cord-005646-xhx9pzhj 780 5 the the DT cord-005646-xhx9pzhj 780 6 ventilator ventilator NN cord-005646-xhx9pzhj 780 7 flow flow NN cord-005646-xhx9pzhj 780 8 pattern pattern NN cord-005646-xhx9pzhj 780 9 showed show VBD cord-005646-xhx9pzhj 780 10 variations variation NNS cord-005646-xhx9pzhj 780 11 at at IN cord-005646-xhx9pzhj 780 12 different different JJ cord-005646-xhx9pzhj 780 13 places place NNS cord-005646-xhx9pzhj 780 14 in in IN cord-005646-xhx9pzhj 780 15 the the DT cord-005646-xhx9pzhj 780 16 ventilator ventilator NN cord-005646-xhx9pzhj 780 17 circuit circuit NN cord-005646-xhx9pzhj 780 18 . . . cord-005646-xhx9pzhj 781 1 The the DT cord-005646-xhx9pzhj 781 2 magnitude magnitude NN cord-005646-xhx9pzhj 781 3 cf cf NN cord-005646-xhx9pzhj 781 4 the the DT cord-005646-xhx9pzhj 781 5 P P NNP cord-005646-xhx9pzhj 781 6 , , , cord-005646-xhx9pzhj 781 7 ow ow UH cord-005646-xhx9pzhj 781 8 change change NN cord-005646-xhx9pzhj 781 9 depended depend VBN cord-005646-xhx9pzhj 781 10 on on IN cord-005646-xhx9pzhj 781 11 the the DT cord-005646-xhx9pzhj 781 12 meas~:rement meas~:rement NNP cord-005646-xhx9pzhj 781 13 site site NN cord-005646-xhx9pzhj 781 14 . . . cord-005646-xhx9pzhj 782 1 The the DT cord-005646-xhx9pzhj 782 2 closer close RBR cord-005646-xhx9pzhj 782 3 to to IN cord-005646-xhx9pzhj 782 4 the the DT cord-005646-xhx9pzhj 782 5 expiratory expiratory JJ cord-005646-xhx9pzhj 782 6 valve valve NN cord-005646-xhx9pzhj 782 7 the the DT cord-005646-xhx9pzhj 782 8 highest high JJS cord-005646-xhx9pzhj 782 9 the the DT cord-005646-xhx9pzhj 782 10 flow flow NN cord-005646-xhx9pzhj 782 11 change change NN cord-005646-xhx9pzhj 782 12 was be VBD cord-005646-xhx9pzhj 782 13 . . . cord-005646-xhx9pzhj 783 1 The the DT cord-005646-xhx9pzhj 783 2 duration duration NN cord-005646-xhx9pzhj 783 3 of of IN cord-005646-xhx9pzhj 783 4 the the DT cord-005646-xhx9pzhj 783 5 flow flow NN cord-005646-xhx9pzhj 783 6 change change NN cord-005646-xhx9pzhj 783 7 was be VBD cord-005646-xhx9pzhj 783 8 inversely inversely RB cord-005646-xhx9pzhj 783 9 proportional proportional JJ cord-005646-xhx9pzhj 783 10 to to IN cord-005646-xhx9pzhj 783 11 the the DT cord-005646-xhx9pzhj 783 12 adjusted adjust VBN cord-005646-xhx9pzhj 783 13 ventilator ventilator NN cord-005646-xhx9pzhj 783 14 flow flow NN cord-005646-xhx9pzhj 783 15 . . . cord-005646-xhx9pzhj 784 1 C C NNP cord-005646-xhx9pzhj 784 2 ) ) -RRB- cord-005646-xhx9pzhj 785 1 Real real JJ cord-005646-xhx9pzhj 785 2 time time NN cord-005646-xhx9pzhj 785 3 measurements measurement NNS cord-005646-xhx9pzhj 785 4 of of IN cord-005646-xhx9pzhj 785 5 the the DT cord-005646-xhx9pzhj 785 6 CO co NN cord-005646-xhx9pzhj 785 7 2 2 CD cord-005646-xhx9pzhj 785 8 concentration concentration NN cord-005646-xhx9pzhj 785 9 ( ( -LRB- cord-005646-xhx9pzhj 785 10 [ [ -LRB- cord-005646-xhx9pzhj 785 11 COz COz NNS cord-005646-xhx9pzhj 785 12 ] ] -RRB- cord-005646-xhx9pzhj 785 13 ) ) -RRB- cord-005646-xhx9pzhj 785 14 showed show VBD cord-005646-xhx9pzhj 785 15 variations variation NNS cord-005646-xhx9pzhj 785 16 during during IN cord-005646-xhx9pzhj 785 17 tile tile NN cord-005646-xhx9pzhj 785 18 respiratory respiratory JJ cord-005646-xhx9pzhj 785 19 cycle cycle NN cord-005646-xhx9pzhj 785 20 . . . cord-005646-xhx9pzhj 786 1 These these DT cord-005646-xhx9pzhj 786 2 [ [ -LRB- cord-005646-xhx9pzhj 786 3 CO2 CO2 NNP cord-005646-xhx9pzhj 786 4 ] ] -RRB- cord-005646-xhx9pzhj 786 5 variations variation NNS cord-005646-xhx9pzhj 786 6 were be VBD cord-005646-xhx9pzhj 786 7 higher high JJR cord-005646-xhx9pzhj 786 8 when when WRB cord-005646-xhx9pzhj 786 9 the the DT cord-005646-xhx9pzhj 786 10 CO2 CO2 NNP cord-005646-xhx9pzhj 786 11 gas gas NN cord-005646-xhx9pzhj 786 12 was be VBD cord-005646-xhx9pzhj 786 13 blended blend VBN cord-005646-xhx9pzhj 786 14 closer close RBR cord-005646-xhx9pzhj 786 15 to to IN cord-005646-xhx9pzhj 786 16 the the DT cord-005646-xhx9pzhj 786 17 Yconnector Yconnector NNP cord-005646-xhx9pzhj 786 18 . . . cord-005646-xhx9pzhj 787 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 787 2 : : : cord-005646-xhx9pzhj 788 1 The the DT cord-005646-xhx9pzhj 788 2 ventilator ventilator NN cord-005646-xhx9pzhj 788 3 flow flow NN cord-005646-xhx9pzhj 788 4 variations variation NNS cord-005646-xhx9pzhj 788 5 in in IN cord-005646-xhx9pzhj 788 6 relation relation NN cord-005646-xhx9pzhj 788 7 to to IN cord-005646-xhx9pzhj 788 8 the the DT cord-005646-xhx9pzhj 788 9 fixed fix VBN cord-005646-xhx9pzhj 788 10 side side NN cord-005646-xhx9pzhj 788 11 flow flow NN cord-005646-xhx9pzhj 788 12 of of IN cord-005646-xhx9pzhj 788 13 the the DT cord-005646-xhx9pzhj 788 14 N2 N2 NNP cord-005646-xhx9pzhj 788 15 / / SYM cord-005646-xhx9pzhj 788 16 NO no DT cord-005646-xhx9pzhj 788 17 gasmixture gasmixture NN cord-005646-xhx9pzhj 788 18 result result VBP cord-005646-xhx9pzhj 788 19 in in IN cord-005646-xhx9pzhj 788 20 changes change NNS cord-005646-xhx9pzhj 788 21 of of IN cord-005646-xhx9pzhj 788 22 the the DT cord-005646-xhx9pzhj 788 23 inhaled inhale VBN cord-005646-xhx9pzhj 788 24 [ [ -LRB- cord-005646-xhx9pzhj 788 25 NO no UH cord-005646-xhx9pzhj 788 26 ] ] -RRB- cord-005646-xhx9pzhj 788 27 during during IN cord-005646-xhx9pzhj 788 28 the the DT cord-005646-xhx9pzhj 788 29 respiratory respiratory JJ cord-005646-xhx9pzhj 788 30 cycle cycle NN cord-005646-xhx9pzhj 788 31 . . . cord-005646-xhx9pzhj 789 1 The the DT cord-005646-xhx9pzhj 789 2 NO no DT cord-005646-xhx9pzhj 789 3 concentration concentration NN cord-005646-xhx9pzhj 789 4 during during IN cord-005646-xhx9pzhj 789 5 inspiration inspiration NN cord-005646-xhx9pzhj 789 6 is be VBZ cord-005646-xhx9pzhj 789 7 always always RB cord-005646-xhx9pzhj 789 8 higher high JJR cord-005646-xhx9pzhj 789 9 then then RB cord-005646-xhx9pzhj 789 10 during during IN cord-005646-xhx9pzhj 789 11 expiration expiration NN cord-005646-xhx9pzhj 789 12 . . . cord-005646-xhx9pzhj 790 1 This this DT cord-005646-xhx9pzhj 790 2 could could MD cord-005646-xhx9pzhj 790 3 not not RB cord-005646-xhx9pzhj 790 4 be be VB cord-005646-xhx9pzhj 790 5 detected detect VBN cord-005646-xhx9pzhj 790 6 with with IN cord-005646-xhx9pzhj 790 7 the the DT cord-005646-xhx9pzhj 790 8 available available JJ cord-005646-xhx9pzhj 790 9 monitoring monitoring NN cord-005646-xhx9pzhj 790 10 system system NN cord-005646-xhx9pzhj 790 11 . . . cord-005646-xhx9pzhj 791 1 To to TO cord-005646-xhx9pzhj 791 2 ensure ensure VB cord-005646-xhx9pzhj 791 3 a a DT cord-005646-xhx9pzhj 791 4 constant constant JJ cord-005646-xhx9pzhj 791 5 [ [ -LRB- cord-005646-xhx9pzhj 791 6 NO no NN cord-005646-xhx9pzhj 791 7 ] ] -RRB- cord-005646-xhx9pzhj 791 8 by by IN cord-005646-xhx9pzhj 791 9 blending blend VBG cord-005646-xhx9pzhj 791 10 a a DT cord-005646-xhx9pzhj 791 11 NJNO NJNO NNP cord-005646-xhx9pzhj 791 12 gas gas NN cord-005646-xhx9pzhj 791 13 balance balance NN cord-005646-xhx9pzhj 791 14 in in IN cord-005646-xhx9pzhj 791 15 a a DT cord-005646-xhx9pzhj 791 16 continuous continuous JJ cord-005646-xhx9pzhj 791 17 flow flow NN cord-005646-xhx9pzhj 791 18 ventilator ventilator NN cord-005646-xhx9pzhj 791 19 , , , cord-005646-xhx9pzhj 791 20 the the DT cord-005646-xhx9pzhj 791 21 site site NN cord-005646-xhx9pzhj 791 22 of of IN cord-005646-xhx9pzhj 791 23 injection injection NN cord-005646-xhx9pzhj 791 24 should should MD cord-005646-xhx9pzhj 791 25 be be VB cord-005646-xhx9pzhj 791 26 as as RB cord-005646-xhx9pzhj 791 27 close close JJ cord-005646-xhx9pzhj 791 28 as as IN cord-005646-xhx9pzhj 791 29 possible possible JJ cord-005646-xhx9pzhj 791 30 to to IN cord-005646-xhx9pzhj 791 31 the the DT cord-005646-xhx9pzhj 791 32 inspiratory inspiratory JJ cord-005646-xhx9pzhj 791 33 outlet outlet NN cord-005646-xhx9pzhj 791 34 . . . cord-005646-xhx9pzhj 792 1 Nitric nitric NN cord-005646-xhx9pzhj 792 2 oxide oxide NN cord-005646-xhx9pzhj 792 3 , , , cord-005646-xhx9pzhj 792 4 a a DT cord-005646-xhx9pzhj 792 5 potent potent JJ cord-005646-xhx9pzhj 792 6 and and CC cord-005646-xhx9pzhj 792 7 selective selective JJ cord-005646-xhx9pzhj 792 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 792 9 vasodilator vasodilator NN cord-005646-xhx9pzhj 792 10 , , , cord-005646-xhx9pzhj 792 11 has have VBZ cord-005646-xhx9pzhj 792 12 recently recently RB cord-005646-xhx9pzhj 792 13 been be VBN cord-005646-xhx9pzhj 792 14 successfully successfully RB cord-005646-xhx9pzhj 792 15 used use VBN cord-005646-xhx9pzhj 792 16 to to TO cord-005646-xhx9pzhj 792 17 treat treat VB cord-005646-xhx9pzhj 792 18 pulmonary pulmonary JJ cord-005646-xhx9pzhj 792 19 hypertension hypertension NN cord-005646-xhx9pzhj 792 20 of of IN cord-005646-xhx9pzhj 792 21 variable variable JJ cord-005646-xhx9pzhj 792 22 etiology etiology NN cord-005646-xhx9pzhj 792 23 in in IN cord-005646-xhx9pzhj 792 24 infants infant NNS cord-005646-xhx9pzhj 792 25 and and CC cord-005646-xhx9pzhj 792 26 children child NNS cord-005646-xhx9pzhj 792 27 . . . cord-005646-xhx9pzhj 793 1 Side side NN cord-005646-xhx9pzhj 793 2 - - HYPH cord-005646-xhx9pzhj 793 3 effects effect NNS cord-005646-xhx9pzhj 793 4 and and CC cord-005646-xhx9pzhj 793 5 complications complication NNS cord-005646-xhx9pzhj 793 6 in in IN cord-005646-xhx9pzhj 793 7 infants infant NNS cord-005646-xhx9pzhj 793 8 are be VBP cord-005646-xhx9pzhj 793 9 so so RB cord-005646-xhx9pzhj 793 10 far far RB cord-005646-xhx9pzhj 793 11 not not RB cord-005646-xhx9pzhj 793 12 well well RB cord-005646-xhx9pzhj 793 13 known known JJ cord-005646-xhx9pzhj 793 14 . . . cord-005646-xhx9pzhj 794 1 We -PRON- PRP cord-005646-xhx9pzhj 794 2 describe describe VBP cord-005646-xhx9pzhj 794 3 here here RB cord-005646-xhx9pzhj 794 4 two two CD cord-005646-xhx9pzhj 794 5 cases case NNS cord-005646-xhx9pzhj 794 6 in in IN cord-005646-xhx9pzhj 794 7 which which WDT cord-005646-xhx9pzhj 794 8 prolonged prolong VBD cord-005646-xhx9pzhj 794 9 ( ( -LRB- cord-005646-xhx9pzhj 794 10 5 5 CD cord-005646-xhx9pzhj 794 11 and-7 and-7 CD cord-005646-xhx9pzhj 794 12 days day NNS cord-005646-xhx9pzhj 794 13 respectively respectively RB cord-005646-xhx9pzhj 794 14 ) ) -RRB- cord-005646-xhx9pzhj 794 15 high high JJ cord-005646-xhx9pzhj 794 16 - - HYPH cord-005646-xhx9pzhj 794 17 dose dose NN cord-005646-xhx9pzhj 794 18 ( ( -LRB- cord-005646-xhx9pzhj 794 19 50 50 CD cord-005646-xhx9pzhj 794 20 -80 -80 NNP cord-005646-xhx9pzhj 794 21 ppm ppm NN cord-005646-xhx9pzhj 794 22 ) ) -RRB- cord-005646-xhx9pzhj 795 1 nitric nitric JJ cord-005646-xhx9pzhj 795 2 oxide oxide NN cord-005646-xhx9pzhj 795 3 was be VBD cord-005646-xhx9pzhj 795 4 used use VBN cord-005646-xhx9pzhj 795 5 to to TO cord-005646-xhx9pzhj 795 6 treat treat VB cord-005646-xhx9pzhj 795 7 refractor~¢ refractor~¢ CD cord-005646-xhx9pzhj 795 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 795 9 hypertension hypertension NN cord-005646-xhx9pzhj 795 10 . . . cord-005646-xhx9pzhj 796 1 One one CD cord-005646-xhx9pzhj 796 2 patient patient NN cord-005646-xhx9pzhj 796 3 was be VBD cord-005646-xhx9pzhj 796 4 a a DT cord-005646-xhx9pzhj 796 5 newborn newborn JJ cord-005646-xhx9pzhj 796 6 infant infant NN cord-005646-xhx9pzhj 796 7 with with IN cord-005646-xhx9pzhj 796 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 796 9 hypertension hypertension NN cord-005646-xhx9pzhj 796 10 secondary secondary JJ cord-005646-xhx9pzhj 796 11 to to IN cord-005646-xhx9pzhj 796 12 a a DT cord-005646-xhx9pzhj 796 13 large large JJ cord-005646-xhx9pzhj 796 14 leftsided leftside VBN cord-005646-xhx9pzhj 796 15 diaphragmatic diaphragmatic JJ cord-005646-xhx9pzhj 796 16 hernia hernia NN cord-005646-xhx9pzhj 796 17 . . . cord-005646-xhx9pzhj 797 1 Nitric nitric NN cord-005646-xhx9pzhj 797 2 oxide oxide NN cord-005646-xhx9pzhj 797 3 was be VBD cord-005646-xhx9pzhj 797 4 begun begin VBN cord-005646-xhx9pzhj 797 5 under under IN cord-005646-xhx9pzhj 797 6 conventional conventional JJ cord-005646-xhx9pzhj 797 7 ventilation ventilation NN cord-005646-xhx9pzhj 797 8 ( ( -LRB- cord-005646-xhx9pzhj 797 9 Babylog Babylog NNP cord-005646-xhx9pzhj 797 10 8000 8000 CD cord-005646-xhx9pzhj 797 11 ) ) -RRB- cord-005646-xhx9pzhj 797 12 at at IN cord-005646-xhx9pzhj 797 13 7 7 CD cord-005646-xhx9pzhj 797 14 hours hour NNS cord-005646-xhx9pzhj 797 15 of of IN cord-005646-xhx9pzhj 797 16 life life NN cord-005646-xhx9pzhj 797 17 with with IN cord-005646-xhx9pzhj 797 18 a a DT cord-005646-xhx9pzhj 797 19 slight slight JJ cord-005646-xhx9pzhj 797 20 initial initial JJ cord-005646-xhx9pzhj 797 21 improvement improvement NN cord-005646-xhx9pzhj 797 22 in in IN cord-005646-xhx9pzhj 797 23 oxygenation oxygenation NN cord-005646-xhx9pzhj 797 24 . . . cord-005646-xhx9pzhj 798 1 He -PRON- PRP cord-005646-xhx9pzhj 798 2 was be VBD cord-005646-xhx9pzhj 798 3 then then RB cord-005646-xhx9pzhj 798 4 placed place VBN cord-005646-xhx9pzhj 798 5 on on IN cord-005646-xhx9pzhj 798 6 oscillation oscillation NN cord-005646-xhx9pzhj 798 7 with with IN cord-005646-xhx9pzhj 798 8 the the DT cord-005646-xhx9pzhj 798 9 same same JJ cord-005646-xhx9pzhj 798 10 nitric nitric NN cord-005646-xhx9pzhj 798 11 oxide oxide NN cord-005646-xhx9pzhj 798 12 concentration concentration NN cord-005646-xhx9pzhj 798 13 due due JJ cord-005646-xhx9pzhj 798 14 to to IN cord-005646-xhx9pzhj 798 15 worsening worsen VBG cord-005646-xhx9pzhj 798 16 respiratory respiratory JJ cord-005646-xhx9pzhj 798 17 failure failure NN cord-005646-xhx9pzhj 798 18 . . . cord-005646-xhx9pzhj 799 1 He -PRON- PRP cord-005646-xhx9pzhj 799 2 died die VBD cord-005646-xhx9pzhj 799 3 on on IN cord-005646-xhx9pzhj 799 4 5th 5th JJ cord-005646-xhx9pzhj 799 5 day day NN cord-005646-xhx9pzhj 799 6 of of IN cord-005646-xhx9pzhj 799 7 life life NN cord-005646-xhx9pzhj 799 8 . . . cord-005646-xhx9pzhj 800 1 Monitored monitored JJ cord-005646-xhx9pzhj 800 2 nitric nitric JJ cord-005646-xhx9pzhj 800 3 dioxide dioxide NN cord-005646-xhx9pzhj 800 4 concentration concentration NN cord-005646-xhx9pzhj 800 5 never never RB cord-005646-xhx9pzhj 800 6 exceeded exceed VBD cord-005646-xhx9pzhj 800 7 4 4 CD cord-005646-xhx9pzhj 800 8 ppm ppm NN cord-005646-xhx9pzhj 800 9 . . . cord-005646-xhx9pzhj 801 1 The the DT cord-005646-xhx9pzhj 801 2 other other JJ cord-005646-xhx9pzhj 801 3 patient patient NN cord-005646-xhx9pzhj 801 4 was be VBD cord-005646-xhx9pzhj 801 5 a a DT cord-005646-xhx9pzhj 801 6 3 3 CD cord-005646-xhx9pzhj 801 7 months month NNS cord-005646-xhx9pzhj 801 8 old old JJ cord-005646-xhx9pzhj 801 9 infant infant NN cord-005646-xhx9pzhj 801 10 with with IN cord-005646-xhx9pzhj 801 11 severe severe JJ cord-005646-xhx9pzhj 801 12 pulmonary pulmonary JJ cord-005646-xhx9pzhj 801 13 hypertension hypertension NN cord-005646-xhx9pzhj 801 14 due due IN cord-005646-xhx9pzhj 801 15 to to IN cord-005646-xhx9pzhj 801 16 a a DT cord-005646-xhx9pzhj 801 17 complete complete JJ cord-005646-xhx9pzhj 801 18 atrioventricular atrioventricular JJ cord-005646-xhx9pzhj 801 19 septal septal JJ cord-005646-xhx9pzhj 801 20 defect defect NN cord-005646-xhx9pzhj 801 21 . . . cord-005646-xhx9pzhj 802 1 He -PRON- PRP cord-005646-xhx9pzhj 802 2 required require VBD cord-005646-xhx9pzhj 802 3 high high JJ cord-005646-xhx9pzhj 802 4 - - HYPH cord-005646-xhx9pzhj 802 5 dose dose NN cord-005646-xhx9pzhj 802 6 nitric nitric NN cord-005646-xhx9pzhj 802 7 oxide oxide NN cord-005646-xhx9pzhj 802 8 to to TO cord-005646-xhx9pzhj 802 9 come come VB cord-005646-xhx9pzhj 802 10 off off RP cord-005646-xhx9pzhj 802 11 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 802 12 bypass bypass NN cord-005646-xhx9pzhj 802 13 after after IN cord-005646-xhx9pzhj 802 14 surgical surgical JJ cord-005646-xhx9pzhj 802 15 repair repair NN cord-005646-xhx9pzhj 802 16 of of IN cord-005646-xhx9pzhj 802 17 his -PRON- PRP$ cord-005646-xhx9pzhj 802 18 heart heart NN cord-005646-xhx9pzhj 802 19 defect defect NN cord-005646-xhx9pzhj 802 20 . . . cord-005646-xhx9pzhj 803 1 He -PRON- PRP cord-005646-xhx9pzhj 803 2 slowly slowly RB cord-005646-xhx9pzhj 803 3 improved improve VBD cord-005646-xhx9pzhj 803 4 over over IN cord-005646-xhx9pzhj 803 5 the the DT cord-005646-xhx9pzhj 803 6 week week NN cord-005646-xhx9pzhj 803 7 following follow VBG cord-005646-xhx9pzhj 803 8 surgery surgery NN cord-005646-xhx9pzhj 803 9 but but CC cord-005646-xhx9pzhj 803 10 developped developpe VBD cord-005646-xhx9pzhj 803 11 suddenly suddenly RB cord-005646-xhx9pzhj 803 12 respiratory respiratory JJ cord-005646-xhx9pzhj 803 13 failure failure NN cord-005646-xhx9pzhj 803 14 due due JJ cord-005646-xhx9pzhj 803 15 to to IN cord-005646-xhx9pzhj 803 16 massive massive JJ cord-005646-xhx9pzhj 803 17 pulmonary pulmonary JJ cord-005646-xhx9pzhj 803 18 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 803 19 and and CC cord-005646-xhx9pzhj 803 20 died die VBD cord-005646-xhx9pzhj 803 21 . . . cord-005646-xhx9pzhj 804 1 Surprisingly surprisingly RB cord-005646-xhx9pzhj 804 2 , , , cord-005646-xhx9pzhj 804 3 a a DT cord-005646-xhx9pzhj 804 4 particular particular JJ cord-005646-xhx9pzhj 804 5 autopsy autopsy JJ cord-005646-xhx9pzhj 804 6 finding finding NN cord-005646-xhx9pzhj 804 7 in in IN cord-005646-xhx9pzhj 804 8 both both DT cord-005646-xhx9pzhj 804 9 infants infant NNS cord-005646-xhx9pzhj 804 10 was be VBD cord-005646-xhx9pzhj 804 11 a a DT cord-005646-xhx9pzhj 804 12 massive massive JJ cord-005646-xhx9pzhj 804 13 acute acute JJ cord-005646-xhx9pzhj 804 14 necrotizing necrotize VBG cord-005646-xhx9pzhj 804 15 tracheobronchitis tracheobronchitis NN cord-005646-xhx9pzhj 804 16 . . . cord-005646-xhx9pzhj 805 1 We -PRON- PRP cord-005646-xhx9pzhj 805 2 conclude conclude VBP cord-005646-xhx9pzhj 805 3 that that IN cord-005646-xhx9pzhj 805 4 nitric nitric NN cord-005646-xhx9pzhj 805 5 oxide oxide NN cord-005646-xhx9pzhj 805 6 is be VBZ cord-005646-xhx9pzhj 805 7 an an DT cord-005646-xhx9pzhj 805 8 excellent excellent JJ cord-005646-xhx9pzhj 805 9 and and CC cord-005646-xhx9pzhj 805 10 sometimes sometimes RB cord-005646-xhx9pzhj 805 11 lifesaving lifesave VBG cord-005646-xhx9pzhj 805 12 treatment treatment NN cord-005646-xhx9pzhj 805 13 of of IN cord-005646-xhx9pzhj 805 14 pulmonary pulmonary JJ cord-005646-xhx9pzhj 805 15 hypertension hypertension NN cord-005646-xhx9pzhj 805 16 in in IN cord-005646-xhx9pzhj 805 17 infants infant NNS cord-005646-xhx9pzhj 805 18 . . . cord-005646-xhx9pzhj 806 1 Tracheobronchitis Tracheobronchitis NNP cord-005646-xhx9pzhj 806 2 has have VBZ cord-005646-xhx9pzhj 806 3 not not RB cord-005646-xhx9pzhj 806 4 yet yet RB cord-005646-xhx9pzhj 806 5 been be VBN cord-005646-xhx9pzhj 806 6 reported report VBN cord-005646-xhx9pzhj 806 7 as as IN cord-005646-xhx9pzhj 806 8 a a DT cord-005646-xhx9pzhj 806 9 possible possible JJ cord-005646-xhx9pzhj 806 10 complication complication NN cord-005646-xhx9pzhj 806 11 of of IN cord-005646-xhx9pzhj 806 12 nitric nitric JJ cord-005646-xhx9pzhj 806 13 oxide oxide NN cord-005646-xhx9pzhj 806 14 administration administration NN cord-005646-xhx9pzhj 806 15 . . . cord-005646-xhx9pzhj 807 1 We -PRON- PRP cord-005646-xhx9pzhj 807 2 suggest suggest VBP cord-005646-xhx9pzhj 807 3 that that IN cord-005646-xhx9pzhj 807 4 caution caution NN cord-005646-xhx9pzhj 807 5 needs need VBZ cord-005646-xhx9pzhj 807 6 to to TO cord-005646-xhx9pzhj 807 7 be be VB cord-005646-xhx9pzhj 807 8 taken take VBN cord-005646-xhx9pzhj 807 9 with with IN cord-005646-xhx9pzhj 807 10 prolonged prolonged JJ cord-005646-xhx9pzhj 807 11 high high JJ cord-005646-xhx9pzhj 807 12 - - HYPH cord-005646-xhx9pzhj 807 13 dose dose NN cord-005646-xhx9pzhj 807 14 administration administration NN cord-005646-xhx9pzhj 807 15 and and CC cord-005646-xhx9pzhj 807 16 this this DT cord-005646-xhx9pzhj 807 17 possible possible JJ cord-005646-xhx9pzhj 807 18 complication complication NN cord-005646-xhx9pzhj 807 19 to to TO cord-005646-xhx9pzhj 807 20 be be VB cord-005646-xhx9pzhj 807 21 looked look VBN cord-005646-xhx9pzhj 807 22 for for IN cord-005646-xhx9pzhj 807 23 at at IN cord-005646-xhx9pzhj 807 24 autopsy autopsy NN cord-005646-xhx9pzhj 807 25 . . . cord-005646-xhx9pzhj 808 1 Introduction introduction NN cord-005646-xhx9pzhj 808 2 : : : cord-005646-xhx9pzhj 809 1 Permissive permissive JJ cord-005646-xhx9pzhj 809 2 hypereapnia hypereapnia NN cord-005646-xhx9pzhj 809 3 ( ( -LRB- cord-005646-xhx9pzhj 809 4 PH PH NNP cord-005646-xhx9pzhj 809 5 ) ) -RRB- cord-005646-xhx9pzhj 809 6 is be VBZ cord-005646-xhx9pzhj 809 7 a a DT cord-005646-xhx9pzhj 809 8 beneficial beneficial JJ cord-005646-xhx9pzhj 809 9 strategy strategy NN cord-005646-xhx9pzhj 809 10 for for IN cord-005646-xhx9pzhj 809 11 patients patient NNS cord-005646-xhx9pzhj 809 12 with with IN cord-005646-xhx9pzhj 809 13 acute acute JJ cord-005646-xhx9pzhj 809 14 respiratory respiratory JJ cord-005646-xhx9pzhj 809 15 distress distress NN cord-005646-xhx9pzhj 809 16 syndrome syndrome NN cord-005646-xhx9pzhj 809 17 ( ( -LRB- cord-005646-xhx9pzhj 809 18 ARDS ARDS NNP cord-005646-xhx9pzhj 809 19 ) ) -RRB- cord-005646-xhx9pzhj 809 20 to to TO cord-005646-xhx9pzhj 809 21 minimize minimize VB cord-005646-xhx9pzhj 809 22 barotrauma barotrauma NN cord-005646-xhx9pzhj 809 23 by by IN cord-005646-xhx9pzhj 809 24 decreasing decrease VBG cord-005646-xhx9pzhj 809 25 the the DT cord-005646-xhx9pzhj 809 26 peak peak JJ cord-005646-xhx9pzhj 809 27 inspiratory inspiratory JJ cord-005646-xhx9pzhj 809 28 pressure pressure NN cord-005646-xhx9pzhj 809 29 ( ( -LRB- cord-005646-xhx9pzhj 809 30 PIP PIP NNP cord-005646-xhx9pzhj 809 31 ) ) -RRB- cord-005646-xhx9pzhj 809 32 . . . cord-005646-xhx9pzhj 810 1 Hypercapnia Hypercapnia NNP cord-005646-xhx9pzhj 810 2 and and CC cord-005646-xhx9pzhj 810 3 hypoxia hypoxia NN cord-005646-xhx9pzhj 810 4 cause cause VB cord-005646-xhx9pzhj 810 5 pulmonary pulmonary JJ cord-005646-xhx9pzhj 810 6 vasoconstriction vasoconstriction NN cord-005646-xhx9pzhj 810 7 , , , cord-005646-xhx9pzhj 810 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 810 9 artery artery NN cord-005646-xhx9pzhj 810 10 ( ( -LRB- cord-005646-xhx9pzhj 810 11 PA PA NNP cord-005646-xhx9pzhj 810 12 ) ) -RRB- cord-005646-xhx9pzhj 810 13 hypertension hypertension NN cord-005646-xhx9pzhj 810 14 , , , cord-005646-xhx9pzhj 810 15 and and CC cord-005646-xhx9pzhj 810 16 , , , cord-005646-xhx9pzhj 810 17 thus thus RB cord-005646-xhx9pzhj 810 18 , , , cord-005646-xhx9pzhj 810 19 an an DT cord-005646-xhx9pzhj 810 20 increased increase VBN cord-005646-xhx9pzhj 810 21 afterload afterload NN cord-005646-xhx9pzhj 810 22 to to IN cord-005646-xhx9pzhj 810 23 the the DT cord-005646-xhx9pzhj 810 24 right right JJ cord-005646-xhx9pzhj 810 25 ventricle ventricle NN cord-005646-xhx9pzhj 810 26 . . . cord-005646-xhx9pzhj 811 1 This this DT cord-005646-xhx9pzhj 811 2 increased increase VBN cord-005646-xhx9pzhj 811 3 afterload afterload NN cord-005646-xhx9pzhj 811 4 may may MD cord-005646-xhx9pzhj 811 5 result result VB cord-005646-xhx9pzhj 811 6 in in IN cord-005646-xhx9pzhj 811 7 increased increase VBN cord-005646-xhx9pzhj 811 8 right right JJ cord-005646-xhx9pzhj 811 9 ventricular ventricular NN cord-005646-xhx9pzhj 811 10 ( ( -LRB- cord-005646-xhx9pzhj 811 11 RV rv NN cord-005646-xhx9pzhj 811 12 ) ) -RRB- cord-005646-xhx9pzhj 811 13 work work NN cord-005646-xhx9pzhj 811 14 load load NN cord-005646-xhx9pzhj 811 15 and and CC cord-005646-xhx9pzhj 811 16 subsequent subsequent JJ cord-005646-xhx9pzhj 811 17 RV RV NNP cord-005646-xhx9pzhj 811 18 dysfunction dysfunction NN cord-005646-xhx9pzhj 811 19 . . . cord-005646-xhx9pzhj 812 1 One one CD cord-005646-xhx9pzhj 812 2 therapeutic therapeutic JJ cord-005646-xhx9pzhj 812 3 approach approach NN cord-005646-xhx9pzhj 812 4 is be VBZ cord-005646-xhx9pzhj 812 5 the the DT cord-005646-xhx9pzhj 812 6 use use NN cord-005646-xhx9pzhj 812 7 of of IN cord-005646-xhx9pzhj 812 8 inhaled inhale VBN cord-005646-xhx9pzhj 812 9 nitric nitric NN cord-005646-xhx9pzhj 812 10 oxide oxide NN cord-005646-xhx9pzhj 812 11 ( ( -LRB- cord-005646-xhx9pzhj 812 12 iNn iNn NNP cord-005646-xhx9pzhj 812 13 ) ) -RRB- cord-005646-xhx9pzhj 812 14 , , , cord-005646-xhx9pzhj 812 15 a a DT cord-005646-xhx9pzhj 812 16 selective selective JJ cord-005646-xhx9pzhj 812 17 PA PA NNP cord-005646-xhx9pzhj 812 18 vasodilator vasodilator NN cord-005646-xhx9pzhj 812 19 . . . cord-005646-xhx9pzhj 813 1 The the DT cord-005646-xhx9pzhj 813 2 objectives objective NNS cord-005646-xhx9pzhj 813 3 of of IN cord-005646-xhx9pzhj 813 4 this this DT cord-005646-xhx9pzhj 813 5 study study NN cord-005646-xhx9pzhj 813 6 were be VBD cord-005646-xhx9pzhj 813 7 to to TO cord-005646-xhx9pzhj 813 8 test test VB cord-005646-xhx9pzhj 813 9 the the DT cord-005646-xhx9pzhj 813 10 hypothesis hypothesis NN cord-005646-xhx9pzhj 813 11 that that IN cord-005646-xhx9pzhj 813 12 in in IN cord-005646-xhx9pzhj 813 13 a a DT cord-005646-xhx9pzhj 813 14 swine swine NN cord-005646-xhx9pzhj 813 15 model model NN cord-005646-xhx9pzhj 813 16 of of IN cord-005646-xhx9pzhj 813 17 ARDS ARDS NNP cord-005646-xhx9pzhj 813 18 with with IN cord-005646-xhx9pzhj 813 19 PH PH NNP cord-005646-xhx9pzhj 813 20 , , , cord-005646-xhx9pzhj 813 21 iNn iNn NNP cord-005646-xhx9pzhj 813 22 would would MD cord-005646-xhx9pzhj 813 23 improve improve VB cord-005646-xhx9pzhj 813 24 RV RV NNP cord-005646-xhx9pzhj 813 25 work work NN cord-005646-xhx9pzhj 813 26 load load NN cord-005646-xhx9pzhj 813 27 and and CC cord-005646-xhx9pzhj 813 28 not not RB cord-005646-xhx9pzhj 813 29 change change VB cord-005646-xhx9pzhj 813 30 intrinsic intrinsic JJ cord-005646-xhx9pzhj 813 31 RV rv NN cord-005646-xhx9pzhj 813 32 contractility contractility NN cord-005646-xhx9pzhj 813 33 . . . cord-005646-xhx9pzhj 814 1 Methods method NNS cord-005646-xhx9pzhj 814 2 : : : cord-005646-xhx9pzhj 814 3 In in IN cord-005646-xhx9pzhj 814 4 11 11 CD cord-005646-xhx9pzhj 814 5 swine swine NNS cord-005646-xhx9pzhj 814 6 ( ( -LRB- cord-005646-xhx9pzhj 814 7 25 25 CD cord-005646-xhx9pzhj 814 8 - - SYM cord-005646-xhx9pzhj 814 9 35 35 CD cord-005646-xhx9pzhj 814 10 kg kg NNS cord-005646-xhx9pzhj 814 11 ) ) -RRB- cord-005646-xhx9pzhj 814 12 , , , cord-005646-xhx9pzhj 814 13 ARDS ARDS NNP cord-005646-xhx9pzhj 814 14 was be VBD cord-005646-xhx9pzhj 814 15 induced induce VBN cord-005646-xhx9pzhj 814 16 by by IN cord-005646-xhx9pzhj 814 17 surfactant surfactant NN cord-005646-xhx9pzhj 814 18 depletion depletion NN cord-005646-xhx9pzhj 814 19 . . . cord-005646-xhx9pzhj 815 1 Hypercapnia Hypercapnia NNP cord-005646-xhx9pzhj 815 2 was be VBD cord-005646-xhx9pzhj 815 3 achieved achieve VBN cord-005646-xhx9pzhj 815 4 by by IN cord-005646-xhx9pzhj 815 5 decreasing decrease VBG cord-005646-xhx9pzhj 815 6 the the DT cord-005646-xhx9pzhj 815 7 PIP PIP NNP cord-005646-xhx9pzhj 815 8 while while IN cord-005646-xhx9pzhj 815 9 increasing increase VBG cord-005646-xhx9pzhj 815 10 the the DT cord-005646-xhx9pzhj 815 11 PEEP peep NN cord-005646-xhx9pzhj 815 12 to to TO cord-005646-xhx9pzhj 815 13 maintain maintain VB cord-005646-xhx9pzhj 815 14 a a DT cord-005646-xhx9pzhj 815 15 constant constant JJ cord-005646-xhx9pzhj 815 16 mean mean JJ cord-005646-xhx9pzhj 815 17 airway airway NN cord-005646-xhx9pzhj 815 18 pressure pressure NN cord-005646-xhx9pzhj 815 19 , , , cord-005646-xhx9pzhj 815 20 inn inn NNP cord-005646-xhx9pzhj 815 21 was be VBD cord-005646-xhx9pzhj 815 22 administered administer VBN cord-005646-xhx9pzhj 815 23 in in IN cord-005646-xhx9pzhj 815 24 concentrations concentration NNS cord-005646-xhx9pzhj 815 25 of of IN cord-005646-xhx9pzhj 815 26 2 2 CD cord-005646-xhx9pzhj 815 27 , , , cord-005646-xhx9pzhj 815 28 5 5 CD cord-005646-xhx9pzhj 815 29 , , , cord-005646-xhx9pzhj 815 30 and and CC cord-005646-xhx9pzhj 815 31 10 10 CD cord-005646-xhx9pzhj 815 32 ppm ppm NN cord-005646-xhx9pzhj 815 33 in in IN cord-005646-xhx9pzhj 815 34 a a DT cord-005646-xhx9pzhj 815 35 random random JJ cord-005646-xhx9pzhj 815 36 order order NN cord-005646-xhx9pzhj 815 37 . . . cord-005646-xhx9pzhj 816 1 Pulmonary pulmonary JJ cord-005646-xhx9pzhj 816 2 blood blood NN cord-005646-xhx9pzhj 816 3 flow flow NN cord-005646-xhx9pzhj 816 4 ( ( -LRB- cord-005646-xhx9pzhj 816 5 Qpa Qpa NNP cord-005646-xhx9pzhj 816 6 ) ) -RRB- cord-005646-xhx9pzhj 816 7 was be VBD cord-005646-xhx9pzhj 816 8 determined determine VBN cord-005646-xhx9pzhj 816 9 by by IN cord-005646-xhx9pzhj 816 10 an an DT cord-005646-xhx9pzhj 816 11 ultrasonic ultrasonic JJ cord-005646-xhx9pzhj 816 12 flow flow NN cord-005646-xhx9pzhj 816 13 probe probe NN cord-005646-xhx9pzhj 816 14 . . . cord-005646-xhx9pzhj 817 1 RV RV NNP cord-005646-xhx9pzhj 817 2 total total JJ cord-005646-xhx9pzhj 817 3 power power NN cord-005646-xhx9pzhj 817 4 ( ( -LRB- cord-005646-xhx9pzhj 817 5 TP TP NNP cord-005646-xhx9pzhj 817 6 ) ) -RRB- cord-005646-xhx9pzhj 817 7 and and CC cord-005646-xhx9pzhj 817 8 stroke stroke NN cord-005646-xhx9pzhj 817 9 work work NN cord-005646-xhx9pzhj 817 10 ( ( -LRB- cord-005646-xhx9pzhj 817 11 SW SW NNP cord-005646-xhx9pzhj 817 12 ) ) -RRB- cord-005646-xhx9pzhj 817 13 were be VBD cord-005646-xhx9pzhj 817 14 calculated calculate VBN cord-005646-xhx9pzhj 817 15 by by IN cord-005646-xhx9pzhj 817 16 Fourier Fourier NNP cord-005646-xhx9pzhj 817 17 transformation transformation NN cord-005646-xhx9pzhj 817 18 of of IN cord-005646-xhx9pzhj 817 19 the the DT cord-005646-xhx9pzhj 817 20 PA PA NNP cord-005646-xhx9pzhj 817 21 pressure pressure NN cord-005646-xhx9pzhj 817 22 ( ( -LRB- cord-005646-xhx9pzhj 817 23 Ppa Ppa NNP cord-005646-xhx9pzhj 817 24 ) ) -RRB- cord-005646-xhx9pzhj 817 25 and and CC cord-005646-xhx9pzhj 817 26 Qpa Qpa NNP cord-005646-xhx9pzhj 817 27 data datum NNS cord-005646-xhx9pzhj 817 28 . . . cord-005646-xhx9pzhj 818 1 Preload preload DT cord-005646-xhx9pzhj 818 2 recruitable recruitable JJ cord-005646-xhx9pzhj 818 3 stroke stroke NN cord-005646-xhx9pzhj 818 4 work work NN cord-005646-xhx9pzhj 818 5 ( ( -LRB- cord-005646-xhx9pzhj 818 6 PRSW PRSW NNP cord-005646-xhx9pzhj 818 7 ) ) -RRB- cord-005646-xhx9pzhj 818 8 , , , cord-005646-xhx9pzhj 818 9 a a DT cord-005646-xhx9pzhj 818 10 preload preload NN cord-005646-xhx9pzhj 818 11 and and CC cord-005646-xhx9pzhj 818 12 afterload afterload NN cord-005646-xhx9pzhj 818 13 independent independent JJ cord-005646-xhx9pzhj 818 14 measure measure NN cord-005646-xhx9pzhj 818 15 of of IN cord-005646-xhx9pzhj 818 16 ventriculur ventriculur NN cord-005646-xhx9pzhj 818 17 contractility contractility NN cord-005646-xhx9pzhj 818 18 , , , cord-005646-xhx9pzhj 818 19 was be VBD cord-005646-xhx9pzhj 818 20 determined determine VBN cord-005646-xhx9pzhj 818 21 by by IN cord-005646-xhx9pzhj 818 22 a a DT cord-005646-xhx9pzhj 818 23 shen shen NN cord-005646-xhx9pzhj 818 24 - - HYPH cord-005646-xhx9pzhj 818 25 subtraction subtraction NN cord-005646-xhx9pzhj 818 26 method method NN cord-005646-xhx9pzhj 818 27 and and CC cord-005646-xhx9pzhj 818 28 vena vena NNP cord-005646-xhx9pzhj 818 29 caval caval NNP cord-005646-xhx9pzhj 818 30 occlusion occlusion NN cord-005646-xhx9pzhj 818 31 . . . cord-005646-xhx9pzhj 818 32 _SP cord-005646-xhx9pzhj 819 1 Respiratory respiratory JJ cord-005646-xhx9pzhj 819 2 Failure failure NN cord-005646-xhx9pzhj 819 3 with with IN cord-005646-xhx9pzhj 819 4 Pulmonary pulmonary JJ cord-005646-xhx9pzhj 819 5 Hypertension hypertension NN cord-005646-xhx9pzhj 819 6 in in IN cord-005646-xhx9pzhj 819 7 Piglets piglet NNS cord-005646-xhx9pzhj 820 1 Gerfried Gerfried NNP cord-005646-xhx9pzhj 820 2 Zobel Zobel NNP cord-005646-xhx9pzhj 821 1 * * NFP cord-005646-xhx9pzhj 821 2 , , , cord-005646-xhx9pzhj 821 3 Bernd Bernd NNP cord-005646-xhx9pzhj 821 4 Urlesberger Urlesberger NNP cord-005646-xhx9pzhj 821 5 * * NFP cord-005646-xhx9pzhj 821 6 , , , cord-005646-xhx9pzhj 821 7 Drago Drago NNP cord-005646-xhx9pzhj 821 8 Dacar Dacar NNP cord-005646-xhx9pzhj 822 1 * * NFP cord-005646-xhx9pzhj 822 2 * * NFP cord-005646-xhx9pzhj 822 3 , , , cord-005646-xhx9pzhj 822 4 Siegfried Siegfried NNP cord-005646-xhx9pzhj 822 5 Rtdl Rtdl NNP cord-005646-xhx9pzhj 822 6 * * NFP cord-005646-xhx9pzhj 822 7 , , , cord-005646-xhx9pzhj 822 8 Fritz Fritz NNP cord-005646-xhx9pzhj 822 9 Reiterer Reiterer NNP cord-005646-xhx9pzhj 822 10 * * NFP cord-005646-xhx9pzhj 822 11 and and CC cord-005646-xhx9pzhj 822 12 Ingeborg Ingeborg NNP cord-005646-xhx9pzhj 822 13 Friehs Friehs NNP cord-005646-xhx9pzhj 823 1 * * NFP cord-005646-xhx9pzhj 823 2 * * NFP cord-005646-xhx9pzhj 823 3 Depamnents Depamnents NNPS cord-005646-xhx9pzhj 823 4 of of IN cord-005646-xhx9pzhj 823 5 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 823 6 * * NFP cord-005646-xhx9pzhj 823 7 and and CC cord-005646-xhx9pzhj 823 8 Cardiac Cardiac NNP cord-005646-xhx9pzhj 823 9 Surgery surgery NN cord-005646-xhx9pzhj 824 1 * * NFP cord-005646-xhx9pzhj 824 2 * * NFP cord-005646-xhx9pzhj 824 3 , , , cord-005646-xhx9pzhj 824 4 University University NNP cord-005646-xhx9pzhj 824 5 of of IN cord-005646-xhx9pzhj 824 6 Graz Graz NNP cord-005646-xhx9pzhj 824 7 , , , cord-005646-xhx9pzhj 825 1 Austria Austria NNP cord-005646-xhx9pzhj 825 2 Objective Objective NNP cord-005646-xhx9pzhj 825 3 : : : cord-005646-xhx9pzhj 825 4 To to TO cord-005646-xhx9pzhj 825 5 evaluate evaluate VB cord-005646-xhx9pzhj 825 6 gas gas NN cord-005646-xhx9pzhj 825 7 exchange exchange NN cord-005646-xhx9pzhj 825 8 , , , cord-005646-xhx9pzhj 825 9 pulmonary pulmonary JJ cord-005646-xhx9pzhj 825 10 mechanics mechanic NNS cord-005646-xhx9pzhj 825 11 and and CC cord-005646-xhx9pzhj 825 12 bemodynamic bemodynamic JJ cord-005646-xhx9pzhj 825 13 data datum NNS cord-005646-xhx9pzhj 825 14 during during IN cord-005646-xhx9pzhj 825 15 partial partial JJ cord-005646-xhx9pzhj 825 16 liquid liquid NN cord-005646-xhx9pzhj 825 17 ventilation ventilation NN cord-005646-xhx9pzhj 825 18 ( ( -LRB- cord-005646-xhx9pzhj 825 19 PLV PLV NNP cord-005646-xhx9pzhj 825 20 ) ) -RRB- cord-005646-xhx9pzhj 825 21 combined combine VBN cord-005646-xhx9pzhj 825 22 with with IN cord-005646-xhx9pzhj 825 23 inhaled inhale VBN cord-005646-xhx9pzhj 825 24 nitric nitric NN cord-005646-xhx9pzhj 825 25 oxide oxide NN cord-005646-xhx9pzhj 825 26 ( ( -LRB- cord-005646-xhx9pzhj 825 27 NO no UH cord-005646-xhx9pzhj 825 28 ) ) -RRB- cord-005646-xhx9pzhj 825 29 in in IN cord-005646-xhx9pzhj 825 30 acute acute JJ cord-005646-xhx9pzhj 825 31 respiratory respiratory JJ cord-005646-xhx9pzhj 825 32 failure failure NN cord-005646-xhx9pzhj 825 33 with with IN cord-005646-xhx9pzhj 825 34 pulmonary pulmonary JJ cord-005646-xhx9pzhj 825 35 hypertension hypertension NN cord-005646-xhx9pzhj 825 36 . . . cord-005646-xhx9pzhj 826 1 Design design NN cord-005646-xhx9pzhj 826 2 : : : cord-005646-xhx9pzhj 826 3 Prospecfive~ Prospecfive~ . cord-005646-xhx9pzhj 827 1 randomized randomized JJ cord-005646-xhx9pzhj 827 2 , , , cord-005646-xhx9pzhj 827 3 controlled controlled JJ cord-005646-xhx9pzhj 827 4 study study NN cord-005646-xhx9pzhj 827 5 . . . cord-005646-xhx9pzhj 828 1 Setting set VBG cord-005646-xhx9pzhj 828 2 : : : cord-005646-xhx9pzhj 828 3 University university NN cord-005646-xhx9pzhj 828 4 research research NN cord-005646-xhx9pzhj 828 5 laboratory laboratory NN cord-005646-xhx9pzhj 828 6 . . . cord-005646-xhx9pzhj 829 1 Subjects subject NNS cord-005646-xhx9pzhj 829 2 : : : cord-005646-xhx9pzhj 830 1 Twelve twelve CD cord-005646-xhx9pzhj 830 2 piglets piglet NNS cord-005646-xhx9pzhj 830 3 weighing weigh VBG cord-005646-xhx9pzhj 830 4 9 9 CD cord-005646-xhx9pzhj 830 5 to to TO cord-005646-xhx9pzhj 830 6 13 13 CD cord-005646-xhx9pzhj 830 7 kg kg NNS cord-005646-xhx9pzhj 830 8 . . . cord-005646-xhx9pzhj 831 1 Interventions intervention NNS cord-005646-xhx9pzhj 831 2 : : : cord-005646-xhx9pzhj 832 1 Acute acute JJ cord-005646-xhx9pzhj 832 2 respiratory respiratory JJ cord-005646-xhx9pzhj 832 3 failure failure NN cord-005646-xhx9pzhj 832 4 with with IN cord-005646-xhx9pzhj 832 5 pulmonary pulmonary JJ cord-005646-xhx9pzhj 832 6 hypertension hypertension NN cord-005646-xhx9pzhj 832 7 was be VBD cord-005646-xhx9pzhj 832 8 induced induce VBN cord-005646-xhx9pzhj 832 9 by by IN cord-005646-xhx9pzhj 832 10 repented repent VBN cord-005646-xhx9pzhj 832 11 lung lung NNP cord-005646-xhx9pzhj 832 12 lavages lavage NNS cord-005646-xhx9pzhj 832 13 and and CC cord-005646-xhx9pzhj 832 14 a a DT cord-005646-xhx9pzhj 832 15 continuous continuous JJ cord-005646-xhx9pzhj 832 16 infusion infusion NN cord-005646-xhx9pzhj 832 17 of of IN cord-005646-xhx9pzhj 832 18 the the DT cord-005646-xhx9pzhj 832 19 stable stable JJ cord-005646-xhx9pzhj 832 20 endoperoxane endoperoxane NNP cord-005646-xhx9pzhj 832 21 analogue analogue NN cord-005646-xhx9pzhj 832 22 of of IN cord-005646-xhx9pzhj 832 23 thromboxane thromboxane NN cord-005646-xhx9pzhj 832 24 . . . cord-005646-xhx9pzhj 833 1 Thereafter thereafter RB cord-005646-xhx9pzhj 833 2 the the DT cord-005646-xhx9pzhj 833 3 animals animal NNS cord-005646-xhx9pzhj 833 4 were be VBD cord-005646-xhx9pzhj 833 5 randomly randomly RB cord-005646-xhx9pzhj 833 6 assigned assign VBN cord-005646-xhx9pzhj 833 7 either either CC cord-005646-xhx9pzhj 833 8 for for IN cord-005646-xhx9pzhj 833 9 PLV PLV NNP cord-005646-xhx9pzhj 833 10 or or CC cord-005646-xhx9pzhj 833 11 conventional conventional JJ cord-005646-xhx9pzhj 833 12 mechanical mechanical JJ cord-005646-xhx9pzhj 833 13 ventilation ventilation NN cord-005646-xhx9pzhj 833 14 . . . cord-005646-xhx9pzhj 834 1 Initially initially RB cord-005646-xhx9pzhj 834 2 perfhiorocarbon perfhiorocarbon VB cord-005646-xhx9pzhj 834 3 liquid liquid NN cord-005646-xhx9pzhj 834 4 ( ( -LRB- cord-005646-xhx9pzhj 834 5 30ml 30ml NN cord-005646-xhx9pzhj 834 6 / / SYM cord-005646-xhx9pzhj 834 7 kg kg NN cord-005646-xhx9pzhj 834 8 ) ) -RRB- cord-005646-xhx9pzhj 834 9 was be VBD cord-005646-xhx9pzhj 834 10 instilled instill VBN cord-005646-xhx9pzhj 834 11 into into IN cord-005646-xhx9pzhj 834 12 the the DT cord-005646-xhx9pzhj 834 13 endotracheal endotracheal NN cord-005646-xhx9pzhj 834 14 tube tube NN cord-005646-xhx9pzhj 834 15 over over IN cord-005646-xhx9pzhj 834 16 5 5 CD cord-005646-xhx9pzhj 834 17 min min NN cord-005646-xhx9pzhj 834 18 followed follow VBN cord-005646-xhx9pzhj 834 19 by by IN cord-005646-xhx9pzhj 834 20 5 5 CD cord-005646-xhx9pzhj 834 21 - - HYPH cord-005646-xhx9pzhj 834 22 10ml 10ml NN cord-005646-xhx9pzhj 834 23 / / SYM cord-005646-xhx9pzhj 834 24 kg~. kg~. XX cord-005646-xhx9pzhj 835 1 All all DT cord-005646-xhx9pzhj 835 2 animals animal NNS cord-005646-xhx9pzhj 835 3 were be VBD cord-005646-xhx9pzhj 835 4 treated treat VBN cord-005646-xhx9pzhj 835 5 with with IN cord-005646-xhx9pzhj 835 6 different different JJ cord-005646-xhx9pzhj 835 7 concentrations concentration NNS cord-005646-xhx9pzhj 835 8 of of IN cord-005646-xhx9pzhj 835 9 NO no NN cord-005646-xhx9pzhj 835 10 ( ( -LRB- cord-005646-xhx9pzhj 835 11 1 1 CD cord-005646-xhx9pzhj 835 12 - - SYM cord-005646-xhx9pzhj 835 13 10 10 CD cord-005646-xhx9pzhj 835 14 - - SYM cord-005646-xhx9pzhj 835 15 20 20 CD cord-005646-xhx9pzhj 835 16 ppm ppm NN cord-005646-xhx9pzhj 835 17 ) ) -RRB- cord-005646-xhx9pzhj 835 18 inhaled inhale VBN cord-005646-xhx9pzhj 835 19 in in IN cord-005646-xhx9pzhj 835 20 random random JJ cord-005646-xhx9pzhj 835 21 order order NN cord-005646-xhx9pzhj 835 22 . . . cord-005646-xhx9pzhj 836 1 Measurements measurement NNS cord-005646-xhx9pzhj 836 2 and and CC cord-005646-xhx9pzhj 836 3 results result NNS cord-005646-xhx9pzhj 836 4 : : : cord-005646-xhx9pzhj 836 5 Continuous continuous JJ cord-005646-xhx9pzhj 836 6 monitoring monitoring NN cord-005646-xhx9pzhj 836 7 included include VBD cord-005646-xhx9pzhj 836 8 ECG ECG NNP cord-005646-xhx9pzhj 836 9 , , , cord-005646-xhx9pzhj 836 10 CVP CVP NNP cord-005646-xhx9pzhj 836 11 , , , cord-005646-xhx9pzhj 836 12 MPAP MPAP NNP cord-005646-xhx9pzhj 836 13 , , , cord-005646-xhx9pzhj 836 14 MAP MAP NNP cord-005646-xhx9pzhj 836 15 , , , cord-005646-xhx9pzhj 836 16 San2 San2 NNP cord-005646-xhx9pzhj 836 17 and and CC cord-005646-xhx9pzhj 836 18 SvO2 SvO2 NNS cord-005646-xhx9pzhj 836 19 measurements measurement NNS cord-005646-xhx9pzhj 836 20 . . . cord-005646-xhx9pzhj 837 1 During during IN cord-005646-xhx9pzhj 837 2 PLV PLV NNP cord-005646-xhx9pzhj 837 3 PaO2 PaO2 NNS cord-005646-xhx9pzhj 837 4 / / SYM cord-005646-xhx9pzhj 837 5 FiO2 FiO2 NNS cord-005646-xhx9pzhj 837 6 increased increase VBD cord-005646-xhx9pzhj 837 7 significantly significantly RB cord-005646-xhx9pzhj 837 8 from from IN cord-005646-xhx9pzhj 837 9 62_+3.2 62_+3.2 CD cord-005646-xhx9pzhj 837 10 mmHg mmHg NNS cord-005646-xhx9pzhj 837 11 to to IN cord-005646-xhx9pzhj 837 12 193±44 193±44 CD cord-005646-xhx9pzhj 837 13 mmHg mmHg NNP cord-005646-xhx9pzhj 837 14 ( ( -LRB- cord-005646-xhx9pzhj 837 15 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 837 16 ) ) -RRB- cord-005646-xhx9pzhj 837 17 within within IN cord-005646-xhx9pzhj 837 18 10 10 CD cord-005646-xhx9pzhj 837 19 rain rain NN cord-005646-xhx9pzhj 837 20 , , , cord-005646-xhx9pzhj 837 21 while while IN cord-005646-xhx9pzhj 837 22 PaO2]FiO2 PaO2]FiO2 NNP cord-005646-xhx9pzhj 837 23 remained remain VBD cord-005646-xhx9pzhj 837 24 constant constant JJ cord-005646-xhx9pzhj 837 25 at at IN cord-005646-xhx9pzhj 837 26 61 61 CD cord-005646-xhx9pzhj 837 27 -+3.3mmHg -+3.3mmHg NNS cord-005646-xhx9pzhj 837 28 . . . cord-005646-xhx9pzhj 838 1 Qs Qs NNP cord-005646-xhx9pzhj 838 2 / / SYM cord-005646-xhx9pzhj 838 3 Qt Qt NNP cord-005646-xhx9pzhj 838 4 decreased decrease VBD cord-005646-xhx9pzhj 838 5 significantly significantly RB cord-005646-xhx9pzhj 838 6 from from IN cord-005646-xhx9pzhj 838 7 48-+4 48-+4 CD cord-005646-xhx9pzhj 838 8 % % NN cord-005646-xhx9pzhj 838 9 to to IN cord-005646-xhx9pzhj 838 10 25-+5 25-+5 CD cord-005646-xhx9pzhj 838 11 % % NN cord-005646-xhx9pzhj 838 12 ( ( -LRB- cord-005646-xhx9pzhj 838 13 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 838 14 ) ) -RRB- cord-005646-xhx9pzhj 838 15 during during IN cord-005646-xhx9pzhj 838 16 PLV PLV NNP cord-005646-xhx9pzhj 838 17 and and CC cord-005646-xhx9pzhj 838 18 did do VBD cord-005646-xhx9pzhj 838 19 not not RB cord-005646-xhx9pzhj 838 20 change change VB cord-005646-xhx9pzhj 838 21 during during IN cord-005646-xhx9pzhj 838 22 conventional conventional JJ cord-005646-xhx9pzhj 838 23 mechanical mechanical JJ cord-005646-xhx9pzhj 838 24 ventilation ventilation NN cord-005646-xhx9pzhj 838 25 . . . cord-005646-xhx9pzhj 839 1 Static static JJ cord-005646-xhx9pzhj 839 2 pulmonary pulmonary JJ cord-005646-xhx9pzhj 839 3 compliance compliance NN cord-005646-xhx9pzhj 839 4 ( ( -LRB- cord-005646-xhx9pzhj 839 5 Cstat Cstat NNP cord-005646-xhx9pzhj 839 6 ) ) -RRB- cord-005646-xhx9pzhj 839 7 increased increase VBD cord-005646-xhx9pzhj 839 8 significantly significantly RB cord-005646-xhx9pzhj 839 9 ff~ ff~ NNP cord-005646-xhx9pzhj 840 1 m m LS cord-005646-xhx9pzhj 840 2 0.4R±0.07 0.4r±0.07 CD cord-005646-xhx9pzhj 841 1 to to IN cord-005646-xhx9pzhj 841 2 0.75_+0.03 0.75_+0.03 CD cord-005646-xhx9pzhj 842 1 ml ml NNP cord-005646-xhx9pzhj 842 2 / / SYM cord-005646-xhx9pzhj 842 3 cmH20 cmH20 NNP cord-005646-xhx9pzhj 842 4 / / SYM cord-005646-xhx9pzhj 842 5 kg kg NNP cord-005646-xhx9pzhj 842 6 ( ( -LRB- cord-005646-xhx9pzhj 842 7 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 842 8 ) ) -RRB- cord-005646-xhx9pzhj 842 9 during during IN cord-005646-xhx9pzhj 842 10 PLV PLV NNP cord-005646-xhx9pzhj 842 11 and and CC cord-005646-xhx9pzhj 842 12 decreased decrease VBD cord-005646-xhx9pzhj 842 13 slightly slightly RB cord-005646-xhx9pzhj 842 14 from from IN cord-005646-xhx9pzhj 842 15 0.58_+0.08 0.58_+0.08 CD cord-005646-xhx9pzhj 842 16 to to IN cord-005646-xhx9pzhj 842 17 0.46e0.04 0.46e0.04 CD cord-005646-xhx9pzhj 842 18 ml ml NN cord-005646-xhx9pzhj 842 19 / / SYM cord-005646-xhx9pzhj 842 20 cmH20 cmH20 NNP cord-005646-xhx9pzhj 842 21 / / SYM cord-005646-xhx9pzhj 842 22 kg kg NNS cord-005646-xhx9pzhj 842 23 during during IN cord-005646-xhx9pzhj 842 24 conventional conventional JJ cord-005646-xhx9pzhj 842 25 mechanical mechanical JJ cord-005646-xhx9pzhj 842 26 ventilation ventilation NN cord-005646-xhx9pzhj 842 27 . . . cord-005646-xhx9pzhj 843 1 The the DT cord-005646-xhx9pzhj 843 2 infusion infusion NN cord-005646-xhx9pzhj 843 3 of of IN cord-005646-xhx9pzhj 843 4 the the DT cord-005646-xhx9pzhj 843 5 endoperoxane endoperoxane NNP cord-005646-xhx9pzhj 843 6 analogue analogue NNP cord-005646-xhx9pzhj 843 7 resulted result VBD cord-005646-xhx9pzhj 843 8 in in IN cord-005646-xhx9pzhj 843 9 a a DT cord-005646-xhx9pzhj 843 10 sudden sudden JJ cord-005646-xhx9pzhj 843 11 decrease decrease NN cord-005646-xhx9pzhj 843 12 of of IN cord-005646-xhx9pzhj 843 13 PaO2 PaO2 NNS cord-005646-xhx9pzhj 843 14 / / SYM cord-005646-xhx9pzhj 843 15 FiO2 FiO2 NNS cord-005646-xhx9pzhj 843 16 from from IN cord-005646-xhx9pzhj 843 17 262_+44 262_+44 NNP cord-005646-xhx9pzhj 843 18 to to IN cord-005646-xhx9pzhj 843 19 106_+8.0 106_+8.0 CD cord-005646-xhx9pzhj 843 20 mmHg mmHg NNS cord-005646-xhx9pzhj 843 21 in in IN cord-005646-xhx9pzhj 843 22 the the DT cord-005646-xhx9pzhj 843 23 PLV PLV NNP cord-005646-xhx9pzhj 843 24 group group NN cord-005646-xhx9pzhj 843 25 and and CC cord-005646-xhx9pzhj 843 26 from from IN cord-005646-xhx9pzhj 843 27 71±7 71±7 CD cord-005646-xhx9pzhj 843 28 to to IN cord-005646-xhx9pzhj 843 29 52+_2.0 52+_2.0 CD cord-005646-xhx9pzhj 843 30 mmHg mmHg NNS cord-005646-xhx9pzhj 843 31 in in IN cord-005646-xhx9pzhj 843 32 the the DT cord-005646-xhx9pzhj 843 33 control control NN cord-005646-xhx9pzhj 843 34 group group NN cord-005646-xhx9pzhj 843 35 . . . cord-005646-xhx9pzhj 844 1 Inhaled inhale VBN cord-005646-xhx9pzhj 844 2 NO no DT cord-005646-xhx9pzhj 844 3 significandy significandy JJ cord-005646-xhx9pzhj 844 4 improved improve VBD cord-005646-xhx9pzhj 844 5 oxygenation oxygenation NN cord-005646-xhx9pzhj 844 6 in in IN cord-005646-xhx9pzhj 844 7 both both DT cord-005646-xhx9pzhj 844 8 groups group NNS cord-005646-xhx9pzhj 845 1 ( ( -LRB- cord-005646-xhx9pzhj 845 2 PaO2 PaO2 NNS cord-005646-xhx9pzhj 845 3 / / SYM cord-005646-xhx9pzhj 845 4 FiO2:344_+38 FiO2:344_+38 NNS cord-005646-xhx9pzhj 845 5 mmHg mmHg NNS cord-005646-xhx9pzhj 845 6 during during IN cord-005646-xhx9pzhj 845 7 PLV PLV NNP cord-005646-xhx9pzhj 845 8 and and CC cord-005646-xhx9pzhj 845 9 196+_.56 196+_.56 CD cord-005646-xhx9pzhj 845 10 mmHg mmHg NNS cord-005646-xhx9pzhj 845 11 during during IN cord-005646-xhx9pzhj 845 12 conventional conventional JJ cord-005646-xhx9pzhj 845 13 mechanical mechanical JJ cord-005646-xhx9pzhj 845 14 ventilation ventilation NN cord-005646-xhx9pzhj 845 15 ) ) -RRB- cord-005646-xhx9pzhj 845 16 . . . cord-005646-xhx9pzhj 846 1 During during IN cord-005646-xhx9pzhj 846 2 inhalation inhalation NN cord-005646-xhx9pzhj 846 3 of of IN cord-005646-xhx9pzhj 846 4 NO NO NNP cord-005646-xhx9pzhj 846 5 MPAP MPAP NNP cord-005646-xhx9pzhj 846 6 decreased decrease VBD cord-005646-xhx9pzhj 846 7 significantly significantly RB cord-005646-xhx9pzhj 846 8 from from IN cord-005646-xhx9pzhj 846 9 57-+2 57-+2 CD cord-005646-xhx9pzhj 846 10 m m NN cord-005646-xhx9pzhj 846 11 35±2 35±2 CD cord-005646-xhx9pzhj 846 12 mmHg mmhg NN cord-005646-xhx9pzhj 846 13 ( ( -LRB- cord-005646-xhx9pzhj 846 14 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 846 15 ) ) -RRB- cord-005646-xhx9pzhj 846 16 in in IN cord-005646-xhx9pzhj 846 17 both both DT cord-005646-xhx9pzhj 846 18 groups group NNS cord-005646-xhx9pzhj 846 19 . . . cord-005646-xhx9pzhj 847 1 There there EX cord-005646-xhx9pzhj 847 2 was be VBD cord-005646-xhx9pzhj 847 3 no no DT cord-005646-xhx9pzhj 847 4 significant significant JJ cord-005646-xhx9pzhj 847 5 change change NN cord-005646-xhx9pzhj 847 6 in in IN cord-005646-xhx9pzhj 847 7 oxygenation oxygenation NN cord-005646-xhx9pzhj 847 8 and and CC cord-005646-xhx9pzhj 847 9 MPAP MPAP NNP cord-005646-xhx9pzhj 847 10 during during IN cord-005646-xhx9pzhj 847 11 inhalation inhalation NN cord-005646-xhx9pzhj 847 12 of of IN cord-005646-xhx9pzhj 847 13 1 1 CD cord-005646-xhx9pzhj 847 14 and and CC cord-005646-xhx9pzhj 847 15 20 20 CD cord-005646-xhx9pzhj 847 16 ppm ppm NN cord-005646-xhx9pzhj 848 1 NO no UH cord-005646-xhx9pzhj 848 2 . . . cord-005646-xhx9pzhj 849 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 849 2 : : : cord-005646-xhx9pzhj 850 1 PLV PLV NNP cord-005646-xhx9pzhj 850 2 significantly significantly RB cord-005646-xhx9pzhj 850 3 improves improve VBZ cord-005646-xhx9pzhj 850 4 oxygenation oxygenation NN cord-005646-xhx9pzhj 850 5 and and CC cord-005646-xhx9pzhj 850 6 pulmonary pulmonary JJ cord-005646-xhx9pzhj 850 7 compliance compliance NN cord-005646-xhx9pzhj 850 8 in in IN cord-005646-xhx9pzhj 850 9 acute acute JJ cord-005646-xhx9pzhj 850 10 respiratory respiratory JJ cord-005646-xhx9pzhj 850 11 failure failure NN cord-005646-xhx9pzhj 850 12 . . . cord-005646-xhx9pzhj 851 1 The the DT cord-005646-xhx9pzhj 851 2 additional additional JJ cord-005646-xhx9pzhj 851 3 application application NN cord-005646-xhx9pzhj 851 4 of of IN cord-005646-xhx9pzhj 851 5 inhaled inhale VBN cord-005646-xhx9pzhj 851 6 NO no RB cord-005646-xhx9pzhj 851 7 further further RB cord-005646-xhx9pzhj 851 8 improves improve VBZ cord-005646-xhx9pzhj 851 9 oxygenation oxygenation NN cord-005646-xhx9pzhj 851 10 and and CC cord-005646-xhx9pzhj 851 11 pulmonary pulmonary JJ cord-005646-xhx9pzhj 851 12 hemodynamics hemodynamic NNS cord-005646-xhx9pzhj 851 13 when when WRB cord-005646-xhx9pzhj 851 14 acute acute JJ cord-005646-xhx9pzhj 851 15 respiratory respiratory JJ cord-005646-xhx9pzhj 851 16 failure failure NN cord-005646-xhx9pzhj 851 17 is be VBZ cord-005646-xhx9pzhj 851 18 associated associate VBN cord-005646-xhx9pzhj 851 19 with with IN cord-005646-xhx9pzhj 851 20 severe severe JJ cord-005646-xhx9pzhj 851 21 pulmonary pulmonary JJ cord-005646-xhx9pzhj 851 22 hypertension hypertension NN cord-005646-xhx9pzhj 851 23 . . . cord-005646-xhx9pzhj 852 1 Inhaled inhale VBN cord-005646-xhx9pzhj 852 2 NO no RB cord-005646-xhx9pzhj 852 3 is be VBZ cord-005646-xhx9pzhj 852 4 very very RB cord-005646-xhx9pzhj 852 5 effective effective JJ cord-005646-xhx9pzhj 852 6 in in IN cord-005646-xhx9pzhj 852 7 improving improve VBG cord-005646-xhx9pzhj 852 8 oxygenation oxygenation NN cord-005646-xhx9pzhj 852 9 and and CC cord-005646-xhx9pzhj 852 10 pulmonary pulmonary JJ cord-005646-xhx9pzhj 852 11 blood blood NN cord-005646-xhx9pzhj 853 1 flow flow VB cord-005646-xhx9pzhj 853 2 even even RB cord-005646-xhx9pzhj 853 3 at at IN cord-005646-xhx9pzhj 853 4 low low JJ cord-005646-xhx9pzhj 853 5 doses dose NNS cord-005646-xhx9pzhj 853 6 . . . cord-005646-xhx9pzhj 854 1 The the DT cord-005646-xhx9pzhj 854 2 work work NN cord-005646-xhx9pzhj 854 3 was be VBD cord-005646-xhx9pzhj 854 4 supported support VBN cord-005646-xhx9pzhj 854 5 in in IN cord-005646-xhx9pzhj 854 6 part part NN cord-005646-xhx9pzhj 854 7 by by IN cord-005646-xhx9pzhj 854 8 grants grant NNS cord-005646-xhx9pzhj 854 9 of of IN cord-005646-xhx9pzhj 854 10 the the DT cord-005646-xhx9pzhj 854 11 Austrian Austrian NNP cord-005646-xhx9pzhj 854 12 Nationalbank Nationalbank NNP cord-005646-xhx9pzhj 854 13 Nr Nr NNP cord-005646-xhx9pzhj 854 14 5545 5545 CD cord-005646-xhx9pzhj 854 15 . . . cord-005646-xhx9pzhj 855 1 As as IN cord-005646-xhx9pzhj 855 2 in in IN cord-005646-xhx9pzhj 855 3 neonates neonate NNS cord-005646-xhx9pzhj 855 4 , , , cord-005646-xhx9pzhj 855 5 severe severe JJ cord-005646-xhx9pzhj 855 6 respiratory respiratory JJ cord-005646-xhx9pzhj 855 7 failure failure NN cord-005646-xhx9pzhj 855 8 in in IN cord-005646-xhx9pzhj 855 9 infants infant NNS cord-005646-xhx9pzhj 855 10 and and CC cord-005646-xhx9pzhj 855 11 children child NNS cord-005646-xhx9pzhj 855 12 can can MD cord-005646-xhx9pzhj 855 13 be be VB cord-005646-xhx9pzhj 855 14 aggravated aggravate VBN cord-005646-xhx9pzhj 855 15 by by IN cord-005646-xhx9pzhj 855 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 855 17 hypertension hypertension NN cord-005646-xhx9pzhj 855 18 , , , cord-005646-xhx9pzhj 855 19 resulting result VBG cord-005646-xhx9pzhj 855 20 in in IN cord-005646-xhx9pzhj 855 21 further further JJ cord-005646-xhx9pzhj 855 22 deterioration deterioration NN cord-005646-xhx9pzhj 855 23 of of IN cord-005646-xhx9pzhj 855 24 oxygenation oxygenation NN cord-005646-xhx9pzhj 855 25 due due IN cord-005646-xhx9pzhj 855 26 to to IN cord-005646-xhx9pzhj 855 27 increasing increase VBG cord-005646-xhx9pzhj 855 28 intrapulmonary intrapulmonary JJ cord-005646-xhx9pzhj 855 29 shunting shunting NN cord-005646-xhx9pzhj 855 30 . . . cord-005646-xhx9pzhj 856 1 We -PRON- PRP cord-005646-xhx9pzhj 856 2 analysed analyse VBD cord-005646-xhx9pzhj 856 3 the the DT cord-005646-xhx9pzhj 856 4 influence influence NN cord-005646-xhx9pzhj 856 5 of of IN cord-005646-xhx9pzhj 856 6 inhalational inhalational JJ cord-005646-xhx9pzhj 856 7 nitric nitric NN cord-005646-xhx9pzhj 856 8 oxide oxide NN cord-005646-xhx9pzhj 856 9 ( ( -LRB- cord-005646-xhx9pzhj 856 10 iNO iNO NNS cord-005646-xhx9pzhj 856 11 ) ) -RRB- cord-005646-xhx9pzhj 856 12 in in IN cord-005646-xhx9pzhj 856 13 treatment treatment NN cord-005646-xhx9pzhj 856 14 , , , cord-005646-xhx9pzhj 856 15 course course NN cord-005646-xhx9pzhj 856 16 and and CC cord-005646-xhx9pzhj 856 17 outcome outcome NN cord-005646-xhx9pzhj 856 18 of of IN cord-005646-xhx9pzhj 856 19 severe severe JJ cord-005646-xhx9pzhj 856 20 ARDS ARDS NNP cord-005646-xhx9pzhj 856 21 in in IN cord-005646-xhx9pzhj 856 22 a a DT cord-005646-xhx9pzhj 856 23 pediatric pediatric JJ cord-005646-xhx9pzhj 856 24 population population NN cord-005646-xhx9pzhj 856 25 . . . cord-005646-xhx9pzhj 857 1 Since since IN cord-005646-xhx9pzhj 857 2 1993 1993 CD cord-005646-xhx9pzhj 857 3 20 20 CD cord-005646-xhx9pzhj 857 4 infants infant NNS cord-005646-xhx9pzhj 857 5 and and CC cord-005646-xhx9pzhj 857 6 children child NNS cord-005646-xhx9pzhj 857 7 ( ( -LRB- cord-005646-xhx9pzhj 857 8 age age NN cord-005646-xhx9pzhj 857 9 : : : cord-005646-xhx9pzhj 857 10 1 1 CD cord-005646-xhx9pzhj 857 11 - - SYM cord-005646-xhx9pzhj 857 12 107 107 CD cord-005646-xhx9pzhj 857 13 months month NNS cord-005646-xhx9pzhj 857 14 ) ) -RRB- cord-005646-xhx9pzhj 857 15 with with IN cord-005646-xhx9pzhj 857 16 ARDS ARDS NNP cord-005646-xhx9pzhj 857 17 and and CC cord-005646-xhx9pzhj 857 18 OI OI NNP cord-005646-xhx9pzhj 857 19 > > XX cord-005646-xhx9pzhj 857 20 15 15 CD cord-005646-xhx9pzhj 857 21 ( ( -LRB- cord-005646-xhx9pzhj 857 22 mean mean VB cord-005646-xhx9pzhj 857 23 value value NN cord-005646-xhx9pzhj 857 24 : : : cord-005646-xhx9pzhj 857 25 32.5± 32.5± CD cord-005646-xhx9pzhj 857 26 11 11 CD cord-005646-xhx9pzhj 857 27 ) ) -RRB- cord-005646-xhx9pzhj 857 28 underwent undergo VBD cord-005646-xhx9pzhj 857 29 a a DT cord-005646-xhx9pzhj 857 30 trial trial NN cord-005646-xhx9pzhj 857 31 with with IN cord-005646-xhx9pzhj 857 32 iNO iNO NNS cord-005646-xhx9pzhj 857 33 ( ( -LRB- cord-005646-xhx9pzhj 857 34 concentration concentration NN cord-005646-xhx9pzhj 857 35 : : : cord-005646-xhx9pzhj 857 36 3 3 CD cord-005646-xhx9pzhj 857 37 , , , cord-005646-xhx9pzhj 857 38 10 10 CD cord-005646-xhx9pzhj 857 39 , , , cord-005646-xhx9pzhj 857 40 30 30 CD cord-005646-xhx9pzhj 857 41 , , , cord-005646-xhx9pzhj 857 42 60 60 CD cord-005646-xhx9pzhj 857 43 and and CC cord-005646-xhx9pzhj 857 44 100 100 CD cord-005646-xhx9pzhj 857 45 ppm ppm NN cord-005646-xhx9pzhj 857 46 ) ) -RRB- cord-005646-xhx9pzhj 857 47 to to TO cord-005646-xhx9pzhj 857 48 prevent prevent VB cord-005646-xhx9pzhj 857 49 further further JJ cord-005646-xhx9pzhj 857 50 respiratory respiratory JJ cord-005646-xhx9pzhj 857 51 failure failure NN cord-005646-xhx9pzhj 857 52 . . . cord-005646-xhx9pzhj 858 1 11 11 CD cord-005646-xhx9pzhj 858 2 patients patient NNS cord-005646-xhx9pzhj 858 3 had have VBD cord-005646-xhx9pzhj 858 4 a a DT cord-005646-xhx9pzhj 858 5 significant significant JJ cord-005646-xhx9pzhj 858 6 improvement improvement NN cord-005646-xhx9pzhj 858 7 of of IN cord-005646-xhx9pzhj 858 8 their -PRON- PRP$ cord-005646-xhx9pzhj 858 9 oxygenation oxygenation NN cord-005646-xhx9pzhj 858 10 ( ( -LRB- cord-005646-xhx9pzhj 858 11 rise rise NN cord-005646-xhx9pzhj 858 12 of of IN cord-005646-xhx9pzhj 858 13 pa09 pa09 NN cord-005646-xhx9pzhj 859 1 > > XX cord-005646-xhx9pzhj 860 1 15 15 CD cord-005646-xhx9pzhj 860 2 mm mm CD cord-005646-xhx9pzhj 860 3 Hg Hg NNP cord-005646-xhx9pzhj 860 4 ) ) -RRB- cord-005646-xhx9pzhj 860 5 for for IN cord-005646-xhx9pzhj 860 6 at at RB cord-005646-xhx9pzhj 860 7 least least RBS cord-005646-xhx9pzhj 860 8 24 24 CD cord-005646-xhx9pzhj 860 9 hours hour NNS cord-005646-xhx9pzhj 860 10 ( ( -LRB- cord-005646-xhx9pzhj 860 11 responders responder NNS cord-005646-xhx9pzhj 860 12 ) ) -RRB- cord-005646-xhx9pzhj 861 1 ; ; : cord-005646-xhx9pzhj 861 2 mean mean VB cord-005646-xhx9pzhj 861 3 best good JJS cord-005646-xhx9pzhj 861 4 ~fficient ~fficient . cord-005646-xhx9pzhj 862 1 NO no DT cord-005646-xhx9pzhj 862 2 dose dose NN cord-005646-xhx9pzhj 862 3 : : : cord-005646-xhx9pzhj 862 4 24.6 24.6 CD cord-005646-xhx9pzhj 862 5 ppm ppm NN cord-005646-xhx9pzhj 862 6 . . . cord-005646-xhx9pzhj 863 1 The the DT cord-005646-xhx9pzhj 863 2 non non JJ cord-005646-xhx9pzhj 863 3 - - NNS cord-005646-xhx9pzhj 863 4 responders responder NNS cord-005646-xhx9pzhj 863 5 had have VBD cord-005646-xhx9pzhj 863 6 only only RB cord-005646-xhx9pzhj 863 7 a a DT cord-005646-xhx9pzhj 863 8 short short JJ cord-005646-xhx9pzhj 863 9 - - HYPH cord-005646-xhx9pzhj 863 10 term term NN cord-005646-xhx9pzhj 863 11 improvement improvement NN cord-005646-xhx9pzhj 863 12 or or CC cord-005646-xhx9pzhj 863 13 iNO iNO NNS cord-005646-xhx9pzhj 863 14 had have VBD cord-005646-xhx9pzhj 863 15 no no DT cord-005646-xhx9pzhj 863 16 effect effect NN cord-005646-xhx9pzhj 863 17 . . . cord-005646-xhx9pzhj 864 1 In in IN cord-005646-xhx9pzhj 864 2 responders responder NNS cord-005646-xhx9pzhj 864 3 and and CC cord-005646-xhx9pzhj 864 4 nonresponders nonresponder NNS cord-005646-xhx9pzhj 864 5 there there EX cord-005646-xhx9pzhj 864 6 was be VBD cord-005646-xhx9pzhj 864 7 no no DT cord-005646-xhx9pzhj 864 8 significant significant JJ cord-005646-xhx9pzhj 864 9 difference difference NN cord-005646-xhx9pzhj 864 10 with with IN cord-005646-xhx9pzhj 864 11 regard regard NN cord-005646-xhx9pzhj 864 12 to to IN cord-005646-xhx9pzhj 864 13 age age NN cord-005646-xhx9pzhj 864 14 , , , cord-005646-xhx9pzhj 864 15 underlying underlie VBG cord-005646-xhx9pzhj 864 16 disease disease NN cord-005646-xhx9pzhj 864 17 , , , cord-005646-xhx9pzhj 864 18 ARDS ARDS NNP cord-005646-xhx9pzhj 864 19 severity severity NN cord-005646-xhx9pzhj 864 20 , , , cord-005646-xhx9pzhj 864 21 time time NN cord-005646-xhx9pzhj 864 22 on on IN cord-005646-xhx9pzhj 864 23 mechanical mechanical JJ cord-005646-xhx9pzhj 864 24 ventilation ventilation NN cord-005646-xhx9pzhj 864 25 , , , cord-005646-xhx9pzhj 864 26 blood blood NN cord-005646-xhx9pzhj 864 27 gases gas NNS cord-005646-xhx9pzhj 864 28 and and CC cord-005646-xhx9pzhj 864 29 ventilator ventilator NN cord-005646-xhx9pzhj 864 30 settings setting NNS cord-005646-xhx9pzhj 864 31 before before IN cord-005646-xhx9pzhj 864 32 NOtrial NOtrial NNP cord-005646-xhx9pzhj 864 33 , , , cord-005646-xhx9pzhj 864 34 nor nor CC cord-005646-xhx9pzhj 864 35 was be VBD cord-005646-xhx9pzhj 864 36 there there EX cord-005646-xhx9pzhj 864 37 a a DT cord-005646-xhx9pzhj 864 38 different different JJ cord-005646-xhx9pzhj 864 39 grade grade NN cord-005646-xhx9pzhj 864 40 of of IN cord-005646-xhx9pzhj 864 41 pulmonary pulmonary JJ cord-005646-xhx9pzhj 864 42 hypertension hypertension NN cord-005646-xhx9pzhj 864 43 ( ( -LRB- cord-005646-xhx9pzhj 864 44 estimated estimate VBN cord-005646-xhx9pzhj 864 45 by by IN cord-005646-xhx9pzhj 864 46 echocardiography echocardiography NN cord-005646-xhx9pzhj 864 47 ) ) -RRB- cord-005646-xhx9pzhj 864 48 . . . cord-005646-xhx9pzhj 865 1 The the DT cord-005646-xhx9pzhj 865 2 only only JJ cord-005646-xhx9pzhj 865 3 difference difference NN cord-005646-xhx9pzhj 865 4 was be VBD cord-005646-xhx9pzhj 865 5 an an DT cord-005646-xhx9pzhj 865 6 higher high JJR cord-005646-xhx9pzhj 865 7 Ol old NNP cord-005646-xhx9pzhj 865 8 in in IN cord-005646-xhx9pzhj 865 9 the the DT cord-005646-xhx9pzhj 865 10 group group NN cord-005646-xhx9pzhj 865 11 of of IN cord-005646-xhx9pzhj 865 12 the the DT cord-005646-xhx9pzhj 865 13 non non NNS cord-005646-xhx9pzhj 865 14 - - NNS cord-005646-xhx9pzhj 865 15 responders responder NNS cord-005646-xhx9pzhj 865 16 : : : cord-005646-xhx9pzhj 865 17 40.9 40.9 CD cord-005646-xhx9pzhj 865 18 ± ± CD cord-005646-xhx9pzhj 865 19 9.I 9.i CD cord-005646-xhx9pzhj 865 20 vs. vs. IN cord-005646-xhx9pzhj 865 21 25.6 25.6 CD cord-005646-xhx9pzhj 865 22 ~ ~ CD cord-005646-xhx9pzhj 865 23 6.7 6.7 CD cord-005646-xhx9pzhj 865 24 , , , cord-005646-xhx9pzhj 865 25 p p NN cord-005646-xhx9pzhj 865 26 < < XX cord-005646-xhx9pzhj 865 27 0.002 0.002 CD cord-005646-xhx9pzhj 865 28 . . . cord-005646-xhx9pzhj 866 1 In in IN cord-005646-xhx9pzhj 866 2 the the DT cord-005646-xhx9pzhj 866 3 group group NN cord-005646-xhx9pzhj 866 4 of of IN cord-005646-xhx9pzhj 866 5 the the DT cord-005646-xhx9pzhj 866 6 11 11 CD cord-005646-xhx9pzhj 866 7 respenders respender NNS cord-005646-xhx9pzhj 866 8 there there EX cord-005646-xhx9pzhj 866 9 was be VBD cord-005646-xhx9pzhj 866 10 a a DT cord-005646-xhx9pzhj 866 11 secondary secondary JJ cord-005646-xhx9pzhj 866 12 deterioration deterioration NN cord-005646-xhx9pzhj 866 13 of of IN cord-005646-xhx9pzhj 866 14 lung lung NN cord-005646-xhx9pzhj 866 15 function function NN cord-005646-xhx9pzhj 866 16 after after IN cord-005646-xhx9pzhj 866 17 I -PRON- PRP cord-005646-xhx9pzhj 866 18 -6 -6 NNP cord-005646-xhx9pzhj 866 19 days day NNS cord-005646-xhx9pzhj 866 20 on on IN cord-005646-xhx9pzhj 866 21 iNO iNO NNS cord-005646-xhx9pzhj 866 22 in in IN cord-005646-xhx9pzhj 866 23 5 5 CD cord-005646-xhx9pzhj 866 24 children child NNS cord-005646-xhx9pzhj 866 25 ( ( -LRB- cord-005646-xhx9pzhj 866 26 transient transient JJ cord-005646-xhx9pzhj 866 27 responders responder NNS cord-005646-xhx9pzhj 866 28 ) ) -RRB- cord-005646-xhx9pzhj 866 29 : : : cord-005646-xhx9pzhj 866 30 in in IN cord-005646-xhx9pzhj 866 31 these these DT cord-005646-xhx9pzhj 866 32 patients patient NNS cord-005646-xhx9pzhj 866 33 , , , cord-005646-xhx9pzhj 866 34 as as RB cord-005646-xhx9pzhj 866 35 well well RB cord-005646-xhx9pzhj 866 36 as as IN cord-005646-xhx9pzhj 866 37 in in IN cord-005646-xhx9pzhj 866 38 the the DT cord-005646-xhx9pzhj 866 39 group group NN cord-005646-xhx9pzhj 866 40 of of IN cord-005646-xhx9pzhj 866 41 the the DT cord-005646-xhx9pzhj 866 42 non non NNS cord-005646-xhx9pzhj 866 43 - - NNS cord-005646-xhx9pzhj 866 44 responders responder NNS cord-005646-xhx9pzhj 866 45 , , , cord-005646-xhx9pzhj 866 46 alternative alternative JJ cord-005646-xhx9pzhj 866 47 modalities modality NNS cord-005646-xhx9pzhj 866 48 of of IN cord-005646-xhx9pzhj 866 49 treatment treatment NN cord-005646-xhx9pzhj 866 50 ( ( -LRB- cord-005646-xhx9pzhj 866 51 HFOV HFOV NNP cord-005646-xhx9pzhj 866 52 and/or and/or CC cord-005646-xhx9pzhj 866 53 ECMO ECMO NNP cord-005646-xhx9pzhj 866 54 ) ) -RRB- cord-005646-xhx9pzhj 866 55 became become VBD cord-005646-xhx9pzhj 866 56 necessary necessary JJ cord-005646-xhx9pzhj 866 57 . . . cord-005646-xhx9pzhj 867 1 6 6 CD cord-005646-xhx9pzhj 867 2 children child NNS cord-005646-xhx9pzhj 867 3 ( ( -LRB- cord-005646-xhx9pzhj 867 4 30 30 CD cord-005646-xhx9pzhj 867 5 % % NN cord-005646-xhx9pzhj 867 6 ) ) -RRB- cord-005646-xhx9pzhj 867 7 died die VBD cord-005646-xhx9pzhj 867 8 : : : cord-005646-xhx9pzhj 867 9 2 2 CD cord-005646-xhx9pzhj 867 10 transient transient JJ cord-005646-xhx9pzhj 867 11 respenders respender NNS cord-005646-xhx9pzhj 867 12 and and CC cord-005646-xhx9pzhj 867 13 4 4 CD cord-005646-xhx9pzhj 867 14 non non NNS cord-005646-xhx9pzhj 867 15 - - NNS cord-005646-xhx9pzhj 867 16 responders responder NNS cord-005646-xhx9pzhj 867 17 . . . cord-005646-xhx9pzhj 868 1 In in IN cord-005646-xhx9pzhj 868 2 infants infant NNS cord-005646-xhx9pzhj 868 3 and and CC cord-005646-xhx9pzhj 868 4 children child NNS cord-005646-xhx9pzhj 868 5 with with IN cord-005646-xhx9pzhj 868 6 ARDS ARDS NNP cord-005646-xhx9pzhj 868 7 due due IN cord-005646-xhx9pzhj 868 8 to to IN cord-005646-xhx9pzhj 868 9 different different JJ cord-005646-xhx9pzhj 868 10 underlying underlying JJ cord-005646-xhx9pzhj 868 11 diseases disease NNS cord-005646-xhx9pzhj 868 12 iNO iNO NNS cord-005646-xhx9pzhj 868 13 can can MD cord-005646-xhx9pzhj 868 14 acutely acutely RB cord-005646-xhx9pzhj 868 15 lead lead VB cord-005646-xhx9pzhj 868 16 to to IN cord-005646-xhx9pzhj 868 17 a a DT cord-005646-xhx9pzhj 868 18 significant significant JJ cord-005646-xhx9pzhj 868 19 improvement improvement NN cord-005646-xhx9pzhj 868 20 of of IN cord-005646-xhx9pzhj 868 21 oxygenation oxygenation NN cord-005646-xhx9pzhj 868 22 in in IN cord-005646-xhx9pzhj 868 23 about about RB cord-005646-xhx9pzhj 868 24 50 50 CD cord-005646-xhx9pzhj 868 25 % % NN cord-005646-xhx9pzhj 868 26 of of IN cord-005646-xhx9pzhj 868 27 the the DT cord-005646-xhx9pzhj 868 28 cases case NNS cord-005646-xhx9pzhj 868 29 . . . cord-005646-xhx9pzhj 869 1 The the DT cord-005646-xhx9pzhj 869 2 right right JJ cord-005646-xhx9pzhj 869 3 selection selection NN cord-005646-xhx9pzhj 869 4 of of IN cord-005646-xhx9pzhj 869 5 patients patient NNS cord-005646-xhx9pzhj 869 6 for for IN cord-005646-xhx9pzhj 869 7 NO no DT cord-005646-xhx9pzhj 869 8 therapy therapy NN cord-005646-xhx9pzhj 869 9 and and CC cord-005646-xhx9pzhj 869 10 the the DT cord-005646-xhx9pzhj 869 11 influence influence NN cord-005646-xhx9pzhj 869 12 of of IN cord-005646-xhx9pzhj 869 13 iNO iNO NNS cord-005646-xhx9pzhj 869 14 on on IN cord-005646-xhx9pzhj 869 15 the the DT cord-005646-xhx9pzhj 869 16 survival survival NN cord-005646-xhx9pzhj 869 17 rate rate NN cord-005646-xhx9pzhj 869 18 of of IN cord-005646-xhx9pzhj 869 19 ARDS ARDS NNP cord-005646-xhx9pzhj 869 20 in in IN cord-005646-xhx9pzhj 869 21 childhood childhood NN cord-005646-xhx9pzhj 869 22 has have VBZ cord-005646-xhx9pzhj 869 23 to to TO cord-005646-xhx9pzhj 869 24 be be VB cord-005646-xhx9pzhj 869 25 evaluated evaluate VBN cord-005646-xhx9pzhj 869 26 in in IN cord-005646-xhx9pzhj 869 27 further further JJ cord-005646-xhx9pzhj 869 28 studies study NNS cord-005646-xhx9pzhj 869 29 . . . cord-005646-xhx9pzhj 870 1 and and CC cord-005646-xhx9pzhj 870 2 Pediatric Pediatric NNP cord-005646-xhx9pzhj 870 3 Cardiology Cardiology NNP cord-005646-xhx9pzhj 870 4 , , , cord-005646-xhx9pzhj 870 5 University University NNP cord-005646-xhx9pzhj 870 6 of of IN cord-005646-xhx9pzhj 870 7 Graz Graz NNP cord-005646-xhx9pzhj 870 8 , , , cord-005646-xhx9pzhj 870 9 A-8036 a-8036 DT cord-005646-xhx9pzhj 870 10 Graz Graz NNP cord-005646-xhx9pzhj 870 11 Purpose Purpose NNP cord-005646-xhx9pzhj 870 12 : : : cord-005646-xhx9pzhj 870 13 After after IN cord-005646-xhx9pzhj 870 14 Fontan Fontan NNP cord-005646-xhx9pzhj 870 15 procedure procedure NN cord-005646-xhx9pzhj 870 16 cardiac cardiac JJ cord-005646-xhx9pzhj 870 17 output output NN cord-005646-xhx9pzhj 870 18 is be VBZ cord-005646-xhx9pzhj 870 19 critically critically RB cord-005646-xhx9pzhj 870 20 dependent dependent JJ cord-005646-xhx9pzhj 870 21 on on IN cord-005646-xhx9pzhj 870 22 the the DT cord-005646-xhx9pzhj 870 23 pulmonary pulmonary JJ cord-005646-xhx9pzhj 870 24 vascular vascular JJ cord-005646-xhx9pzhj 870 25 resistance resistance NN cord-005646-xhx9pzhj 870 26 . . . cord-005646-xhx9pzhj 871 1 Even even RB cord-005646-xhx9pzhj 871 2 minor minor JJ cord-005646-xhx9pzhj 871 3 elevations elevation NNS cord-005646-xhx9pzhj 871 4 of of IN cord-005646-xhx9pzhj 871 5 the the DT cord-005646-xhx9pzhj 871 6 pulmonary pulmonary JJ cord-005646-xhx9pzhj 871 7 vascular vascular JJ cord-005646-xhx9pzhj 871 8 resistance resistance NN cord-005646-xhx9pzhj 871 9 may may MD cord-005646-xhx9pzhj 871 10 significantly significantly RB cord-005646-xhx9pzhj 871 11 decrease decrease VB cord-005646-xhx9pzhj 871 12 cardiac cardiac JJ cord-005646-xhx9pzhj 871 13 output output NN cord-005646-xhx9pzhj 871 14 . . . cord-005646-xhx9pzhj 872 1 Inhaled inhale VBN cord-005646-xhx9pzhj 872 2 NO no RB cord-005646-xhx9pzhj 872 3 is be VBZ cord-005646-xhx9pzhj 872 4 an an DT cord-005646-xhx9pzhj 872 5 effective effective JJ cord-005646-xhx9pzhj 872 6 , , , cord-005646-xhx9pzhj 872 7 selective selective JJ cord-005646-xhx9pzhj 872 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 872 9 vasodilator vasodilator NN cord-005646-xhx9pzhj 872 10 in in IN cord-005646-xhx9pzhj 872 11 experimental experimental JJ cord-005646-xhx9pzhj 872 12 and and CC cord-005646-xhx9pzhj 872 13 clinical clinical JJ cord-005646-xhx9pzhj 872 14 situations situation NNS cord-005646-xhx9pzhj 872 15 of of IN cord-005646-xhx9pzhj 872 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 872 17 hypertension hypertension NN cord-005646-xhx9pzhj 872 18 . . . cord-005646-xhx9pzhj 873 1 The the DT cord-005646-xhx9pzhj 873 2 aim aim NN cord-005646-xhx9pzhj 873 3 of of IN cord-005646-xhx9pzhj 873 4 this this DT cord-005646-xhx9pzhj 873 5 study study NN cord-005646-xhx9pzhj 873 6 is be VBZ cord-005646-xhx9pzhj 873 7 to to TO cord-005646-xhx9pzhj 873 8 evaluate evaluate VB cord-005646-xhx9pzhj 873 9 the the DT cord-005646-xhx9pzhj 873 10 effects effect NNS cord-005646-xhx9pzhj 873 11 of of IN cord-005646-xhx9pzhj 873 12 inhaled inhale VBN cord-005646-xhx9pzhj 873 13 NO no RB cord-005646-xhx9pzhj 873 14 on on IN cord-005646-xhx9pzhj 873 15 oxygenation oxygenation NN cord-005646-xhx9pzhj 873 16 and and CC cord-005646-xhx9pzhj 873 17 pulmonm pulmonm NN cord-005646-xhx9pzhj 873 18 3 3 CD cord-005646-xhx9pzhj 873 19 , , , cord-005646-xhx9pzhj 873 20 circulation circulation NN cord-005646-xhx9pzhj 873 21 in in IN cord-005646-xhx9pzhj 873 22 children child NNS cord-005646-xhx9pzhj 873 23 after after IN cord-005646-xhx9pzhj 873 24 a a DT cord-005646-xhx9pzhj 873 25 bidirectional bidirectional JJ cord-005646-xhx9pzhj 873 26 Glenn Glenn NNP cord-005646-xhx9pzhj 873 27 - - HYPH cord-005646-xhx9pzhj 873 28 anastomosis anastomosis NN cord-005646-xhx9pzhj 873 29 ( ( -LRB- cord-005646-xhx9pzhj 873 30 n-~ n-~ NNP cord-005646-xhx9pzhj 873 31 ) ) -RRB- cord-005646-xhx9pzhj 873 32 or or CC cord-005646-xhx9pzhj 873 33 a a DT cord-005646-xhx9pzhj 873 34 Fontan Fontan NNP cord-005646-xhx9pzhj 873 35 - - HYPH cord-005646-xhx9pzhj 873 36 like like JJ cord-005646-xhx9pzhj 873 37 operation operation NN cord-005646-xhx9pzhj 873 38 ( ( -LRB- cord-005646-xhx9pzhj 873 39 n=9 n=9 NN cord-005646-xhx9pzhj 873 40 ) ) -RRB- cord-005646-xhx9pzhj 873 41 . . . cord-005646-xhx9pzhj 874 1 Material material NN cord-005646-xhx9pzhj 874 2 and and CC cord-005646-xhx9pzhj 874 3 methods method NNS cord-005646-xhx9pzhj 874 4 : : : cord-005646-xhx9pzhj 874 5 From from IN cord-005646-xhx9pzhj 874 6 June June NNP cord-005646-xhx9pzhj 874 7 t993 t993 NNP cord-005646-xhx9pzhj 874 8 to to IN cord-005646-xhx9pzhj 874 9 January January NNP cord-005646-xhx9pzhj 874 10 1996 1996 CD cord-005646-xhx9pzhj 874 11 13 13 CD cord-005646-xhx9pzhj 874 12 children child NNS cord-005646-xhx9pzhj 874 13 with with IN cord-005646-xhx9pzhj 874 14 a a DT cord-005646-xhx9pzhj 874 15 mean mean JJ cord-005646-xhx9pzhj 874 16 age age NN cord-005646-xhx9pzhj 874 17 of of IN cord-005646-xhx9pzhj 874 18 7.1+~2.1 7.1+~2.1 CD cord-005646-xhx9pzhj 874 19 ( ( -LRB- cord-005646-xhx9pzhj 874 20 SEM SEM NNP cord-005646-xhx9pzhj 874 21 ) ) -RRB- cord-005646-xhx9pzhj 874 22 yrs yrs NNP cord-005646-xhx9pzhj 874 23 and and CC cord-005646-xhx9pzhj 874 24 a a DT cord-005646-xhx9pzhj 874 25 mean mean JJ cord-005646-xhx9pzhj 874 26 body body NN cord-005646-xhx9pzhj 874 27 weight weight NN cord-005646-xhx9pzhj 874 28 of of IN cord-005646-xhx9pzhj 874 29 24.3-+5.8 24.3-+5.8 CD cord-005646-xhx9pzhj 874 30 ( ( -LRB- cord-005646-xhx9pzhj 874 31 SEM SEM NNP cord-005646-xhx9pzhj 874 32 ) ) -RRB- cord-005646-xhx9pzhj 874 33 kg kg NNS cord-005646-xhx9pzhj 874 34 were be VBD cord-005646-xhx9pzhj 874 35 treated treat VBN cord-005646-xhx9pzhj 874 36 with with IN cord-005646-xhx9pzhj 874 37 inhaled inhale VBN cord-005646-xhx9pzhj 874 38 NO no RB cord-005646-xhx9pzhj 874 39 after after IN cord-005646-xhx9pzhj 874 40 Glenn Glenn NNP cord-005646-xhx9pzhj 874 41 - - : cord-005646-xhx9pzhj 874 42 or or CC cord-005646-xhx9pzhj 874 43 Fontan Fontan NNP cord-005646-xhx9pzhj 874 44 - - HYPH cord-005646-xhx9pzhj 874 45 like like JJ cord-005646-xhx9pzhj 874 46 operations operation NNS cord-005646-xhx9pzhj 874 47 . . . cord-005646-xhx9pzhj 875 1 All all DT cord-005646-xhx9pzhj 875 2 but but IN cord-005646-xhx9pzhj 875 3 one one PRP cord-005646-xhx9pzhj 875 4 had have VBD cord-005646-xhx9pzhj 875 5 complex complex JJ cord-005646-xhx9pzhj 875 6 cardiac cardiac JJ cord-005646-xhx9pzhj 875 7 malformations malformation NNS cord-005646-xhx9pzhj 875 8 with with IN cord-005646-xhx9pzhj 875 9 single single JJ cord-005646-xhx9pzhj 875 10 ventricle ventricle NN cord-005646-xhx9pzhj 875 11 . . . cord-005646-xhx9pzhj 876 1 All all DT cord-005646-xhx9pzhj 876 2 children child NNS cord-005646-xhx9pzhj 876 3 were be VBD cord-005646-xhx9pzhj 876 4 mechanically mechanically RB cord-005646-xhx9pzhj 876 5 ventilated ventilate VBN cord-005646-xhx9pzhj 876 6 with with IN cord-005646-xhx9pzhj 876 7 an an DT cord-005646-xhx9pzhj 876 8 Fin2 Fin2 NNP cord-005646-xhx9pzhj 876 9 > > XX cord-005646-xhx9pzhj 876 10 0.75 0.75 CD cord-005646-xhx9pzhj 876 11 . . . cord-005646-xhx9pzhj 877 1 Inhaled inhale VBN cord-005646-xhx9pzhj 877 2 ( ( -LRB- cord-005646-xhx9pzhj 877 3 NO no UH cord-005646-xhx9pzhj 877 4 ) ) -RRB- cord-005646-xhx9pzhj 877 5 was be VBD cord-005646-xhx9pzhj 877 6 applied apply VBN cord-005646-xhx9pzhj 877 7 using use VBG cord-005646-xhx9pzhj 877 8 a a DT cord-005646-xhx9pzhj 877 9 rrdcrdproeessor rrdcrdproeessor NN cord-005646-xhx9pzhj 877 10 based base VBN cord-005646-xhx9pzhj 877 11 system system NN cord-005646-xhx9pzhj 877 12 which which WDT cord-005646-xhx9pzhj 877 13 additionally additionally RB cord-005646-xhx9pzhj 877 14 allowed allow VBD cord-005646-xhx9pzhj 877 15 measurement measurement NN cord-005646-xhx9pzhj 877 16 of of IN cord-005646-xhx9pzhj 877 17 NO NO NNP cord-005646-xhx9pzhj 877 18 / / SYM cord-005646-xhx9pzhj 877 19 NOx NOx NNS cord-005646-xhx9pzhj 877 20 using use VBG cord-005646-xhx9pzhj 877 21 the the DT cord-005646-xhx9pzhj 877 22 chemihimniscence chemihimniscence NN cord-005646-xhx9pzhj 877 23 method method NN cord-005646-xhx9pzhj 877 24 . . . cord-005646-xhx9pzhj 878 1 Methemogtobin Methemogtobin NNP cord-005646-xhx9pzhj 878 2 concentrations concentration NNS cord-005646-xhx9pzhj 878 3 were be VBD cord-005646-xhx9pzhj 878 4 determined determine VBN cord-005646-xhx9pzhj 878 5 3 3 CD cord-005646-xhx9pzhj 878 6 times time NNS cord-005646-xhx9pzhj 878 7 a a DT cord-005646-xhx9pzhj 878 8 day day NN cord-005646-xhx9pzhj 878 9 . . . cord-005646-xhx9pzhj 879 1 The the DT cord-005646-xhx9pzhj 879 2 major major JJ cord-005646-xhx9pzhj 879 3 indication indication NN cord-005646-xhx9pzhj 879 4 for for IN cord-005646-xhx9pzhj 879 5 postoperative postoperative JJ cord-005646-xhx9pzhj 879 6 inhalation inhalation NN cord-005646-xhx9pzhj 879 7 of of IN cord-005646-xhx9pzhj 879 8 NO NO NNP cord-005646-xhx9pzhj 879 9 was be VBD cord-005646-xhx9pzhj 879 10 a a DT cord-005646-xhx9pzhj 879 11 high high JJ cord-005646-xhx9pzhj 879 12 ( ( -LRB- cord-005646-xhx9pzhj 879 13 > > XX cord-005646-xhx9pzhj 880 1 10mmHg 10mmhg LS cord-005646-xhx9pzhj 880 2 ) ) -RRB- cord-005646-xhx9pzhj 880 3 transpulmonary transpulmonary NNP cord-005646-xhx9pzhj 880 4 pressure pressure NN cord-005646-xhx9pzhj 880 5 gradient gradient NN cord-005646-xhx9pzhj 880 6 ( ( -LRB- cord-005646-xhx9pzhj 880 7 TPG TPG NNP cord-005646-xhx9pzhj 880 8 -- -- : cord-005646-xhx9pzhj 880 9 CVP cvp NN cord-005646-xhx9pzhj 880 10 - - HYPH cord-005646-xhx9pzhj 880 11 LAP LAP NNP cord-005646-xhx9pzhj 880 12 ) ) -RRB- cord-005646-xhx9pzhj 880 13 . . . cord-005646-xhx9pzhj 881 1 Severe severe JJ cord-005646-xhx9pzhj 881 2 myocardial myocardial JJ cord-005646-xhx9pzhj 881 3 dysfunction dysfunction NN cord-005646-xhx9pzhj 881 4 of of IN cord-005646-xhx9pzhj 881 5 the the DT cord-005646-xhx9pzhj 881 6 single single JJ cord-005646-xhx9pzhj 881 7 ventricle ventricle NN cord-005646-xhx9pzhj 881 8 was be VBD cord-005646-xhx9pzhj 881 9 excluded exclude VBN cord-005646-xhx9pzhj 881 10 by by IN cord-005646-xhx9pzhj 881 11 echocardiography echocardiography NN cord-005646-xhx9pzhj 881 12 . . . cord-005646-xhx9pzhj 882 1 Results result NNS cord-005646-xhx9pzhj 882 2 : : : cord-005646-xhx9pzhj 883 1 The the DT cord-005646-xhx9pzhj 883 2 mean mean JJ cord-005646-xhx9pzhj 883 3 duration duration NN cord-005646-xhx9pzhj 883 4 of of IN cord-005646-xhx9pzhj 883 5 mechanical mechanical JJ cord-005646-xhx9pzhj 883 6 ventilation ventilation NN cord-005646-xhx9pzhj 883 7 was be VBD cord-005646-xhx9pzhj 883 8 8.1_+2.2 8.1_+2.2 CD cord-005646-xhx9pzhj 884 1 ( ( -LRB- cord-005646-xhx9pzhj 884 2 SEM SEM NNP cord-005646-xhx9pzhj 884 3 ) ) -RRB- cord-005646-xhx9pzhj 884 4 days day NNS cord-005646-xhx9pzhj 885 1 The the DT cord-005646-xhx9pzhj 885 2 . . . cord-005646-xhx9pzhj 886 1 mean mean VB cord-005646-xhx9pzhj 887 1 dose dose NN cord-005646-xhx9pzhj 887 2 of of IN cord-005646-xhx9pzhj 887 3 inhaled inhale VBN cord-005646-xhx9pzhj 887 4 NO NO NNP cord-005646-xhx9pzhj 887 5 was be VBD cord-005646-xhx9pzhj 887 6 4.4-+0.8 4.4-+0.8 CD cord-005646-xhx9pzhj 888 1 ( ( -LRB- cord-005646-xhx9pzhj 888 2 SEM SEM NNP cord-005646-xhx9pzhj 888 3 ) ) -RRB- cord-005646-xhx9pzhj 889 1 ppm ppm NN cord-005646-xhx9pzhj 889 2 , , , cord-005646-xhx9pzhj 889 3 the the DT cord-005646-xhx9pzhj 889 4 mean mean JJ cord-005646-xhx9pzhj 889 5 duration duration NN cord-005646-xhx9pzhj 889 6 of of IN cord-005646-xhx9pzhj 889 7 NO no DT cord-005646-xhx9pzhj 889 8 - - HYPH cord-005646-xhx9pzhj 889 9 inhalation inhalation NN cord-005646-xhx9pzhj 889 10 was be VBD cord-005646-xhx9pzhj 889 11 106_+19 106_+19 NNP cord-005646-xhx9pzhj 889 12 ( ( -LRB- cord-005646-xhx9pzhj 889 13 SEM SEM NNP cord-005646-xhx9pzhj 889 14 ) ) -RRB- cord-005646-xhx9pzhj 889 15 hours hour NNS cord-005646-xhx9pzhj 889 16 . . . cord-005646-xhx9pzhj 890 1 The the DT cord-005646-xhx9pzhj 890 2 mean mean JJ cord-005646-xhx9pzhj 890 3 methemoglobin methemoglobin JJ cord-005646-xhx9pzhj 890 4 concentration concentration NN cord-005646-xhx9pzhj 890 5 was be VBD cord-005646-xhx9pzhj 890 6 1.2-+0.2 1.2-+0.2 JJ cord-005646-xhx9pzhj 890 7 ( ( -LRB- cord-005646-xhx9pzhj 890 8 SEM)% sem)% NN cord-005646-xhx9pzhj 890 9 . . . cord-005646-xhx9pzhj 891 1 Hemodynamic Hemodynamic NNP cord-005646-xhx9pzhj 891 2 data datum NNS cord-005646-xhx9pzhj 891 3 and and CC cord-005646-xhx9pzhj 891 4 arterial arterial JJ cord-005646-xhx9pzhj 891 5 oxygen oxygen NN cord-005646-xhx9pzhj 891 6 saturation saturation NN cord-005646-xhx9pzhj 891 7 before before IN cord-005646-xhx9pzhj 891 8 inhaling inhale VBG cord-005646-xhx9pzhj 891 9 NO no NN cord-005646-xhx9pzhj 891 10 and and CC cord-005646-xhx9pzhj 891 11 15 15 CD cord-005646-xhx9pzhj 891 12 minutes minute NNS cord-005646-xhx9pzhj 891 13 later later RB cord-005646-xhx9pzhj 891 14 are be VBP cord-005646-xhx9pzhj 891 15 given give VBN cord-005646-xhx9pzhj 891 16 in in IN cord-005646-xhx9pzhj 891 17 Table Table NNP cord-005646-xhx9pzhj 891 18 1 1 CD cord-005646-xhx9pzhj 891 19 Acute acute JJ cord-005646-xhx9pzhj 891 20 hypoxaemic hypoxaemic JJ cord-005646-xhx9pzhj 891 21 respiratory respiratory JJ cord-005646-xhx9pzhj 891 22 failure failure NN cord-005646-xhx9pzhj 891 23 ( ( -LRB- cord-005646-xhx9pzhj 891 24 AHRF AHRF NNP cord-005646-xhx9pzhj 891 25 ) ) -RRB- cord-005646-xhx9pzhj 891 26 in in IN cord-005646-xhx9pzhj 891 27 children child NNS cord-005646-xhx9pzhj 891 28 occurs occur VBZ cord-005646-xhx9pzhj 891 29 in in IN cord-005646-xhx9pzhj 891 30 a a DT cord-005646-xhx9pzhj 891 31 heterogenous heterogenous JJ cord-005646-xhx9pzhj 891 32 group group NN cord-005646-xhx9pzhj 891 33 of of IN cord-005646-xhx9pzhj 891 34 diseases disease NNS cord-005646-xhx9pzhj 891 35 with with IN cord-005646-xhx9pzhj 891 36 pulmonary pulmonary JJ cord-005646-xhx9pzhj 891 37 pathophysiological pathophysiological JJ cord-005646-xhx9pzhj 891 38 processes process NNS cord-005646-xhx9pzhj 891 39 ranging range VBG cord-005646-xhx9pzhj 891 40 from from IN cord-005646-xhx9pzhj 891 41 reversible reversible JJ cord-005646-xhx9pzhj 891 42 physiological physiological JJ cord-005646-xhx9pzhj 891 43 intrapulmonary intrapulmonary JJ cord-005646-xhx9pzhj 891 44 shunting shunt VBG cord-005646-xhx9pzhj 891 45 to to IN cord-005646-xhx9pzhj 891 46 fixed fix VBN cord-005646-xhx9pzhj 891 47 structural structural JJ cord-005646-xhx9pzhj 891 48 lung lung NN cord-005646-xhx9pzhj 891 49 damage damage NN cord-005646-xhx9pzhj 891 50 . . . cord-005646-xhx9pzhj 892 1 We -PRON- PRP cord-005646-xhx9pzhj 892 2 hypothesized hypothesize VBD cord-005646-xhx9pzhj 892 3 that that IN cord-005646-xhx9pzhj 892 4 inhaled inhale VBN cord-005646-xhx9pzhj 892 5 nitric nitric NN cord-005646-xhx9pzhj 892 6 oxide oxide NN cord-005646-xhx9pzhj 892 7 ( ( -LRB- cord-005646-xhx9pzhj 892 8 iNO iNO NNS cord-005646-xhx9pzhj 892 9 ) ) -RRB- cord-005646-xhx9pzhj 892 10 , , , cord-005646-xhx9pzhj 892 11 a a DT cord-005646-xhx9pzhj 892 12 selective selective JJ cord-005646-xhx9pzhj 892 13 pulmonary pulmonary JJ cord-005646-xhx9pzhj 892 14 vasodilator vasodilator NN cord-005646-xhx9pzhj 892 15 , , , cord-005646-xhx9pzhj 892 16 might may MD cord-005646-xhx9pzhj 892 17 identify identify VB cord-005646-xhx9pzhj 892 18 those those DT cord-005646-xhx9pzhj 892 19 patients patient NNS cord-005646-xhx9pzhj 892 20 with with IN cord-005646-xhx9pzhj 892 21 potentially potentially RB cord-005646-xhx9pzhj 892 22 reversible reversible JJ cord-005646-xhx9pzhj 892 23 disease disease NN cord-005646-xhx9pzhj 892 24 , , , cord-005646-xhx9pzhj 892 25 i i PRP cord-005646-xhx9pzhj 892 26 , , , cord-005646-xhx9pzhj 892 27 e e LS cord-005646-xhx9pzhj 892 28 , , , cord-005646-xhx9pzhj 892 29 large large JJ cord-005646-xhx9pzhj 892 30 response response NN cord-005646-xhx9pzhj 892 31 may may MD cord-005646-xhx9pzhj 892 32 indicate indicate VB cord-005646-xhx9pzhj 892 33 a a DT cord-005646-xhx9pzhj 892 34 greater great JJR cord-005646-xhx9pzhj 892 35 likelihood likelihood NN cord-005646-xhx9pzhj 892 36 ef ef NNP cord-005646-xhx9pzhj 892 37 reversibility reversibility NN cord-005646-xhx9pzhj 892 38 and and CC cord-005646-xhx9pzhj 892 39 thus thus RB cord-005646-xhx9pzhj 892 40 survival survival NN cord-005646-xhx9pzhj 892 41 . . . cord-005646-xhx9pzhj 893 1 A a DT cord-005646-xhx9pzhj 893 2 retrospective retrospective JJ cord-005646-xhx9pzhj 893 3 review review NN cord-005646-xhx9pzhj 893 4 of of IN cord-005646-xhx9pzhj 893 5 the the DT cord-005646-xhx9pzhj 893 6 early early JJ cord-005646-xhx9pzhj 893 7 response response NN cord-005646-xhx9pzhj 893 8 to to IN cord-005646-xhx9pzhj 893 9 iNO iNO NNS cord-005646-xhx9pzhj 893 10 in in IN cord-005646-xhx9pzhj 893 11 30 30 CD cord-005646-xhx9pzhj 893 12 infants infant NNS cord-005646-xhx9pzhj 893 13 and and CC cord-005646-xhx9pzhj 893 14 children child NNS cord-005646-xhx9pzhj 893 15 ( ( -LRB- cord-005646-xhx9pzhj 893 16 aged aged JJ cord-005646-xhx9pzhj 893 17 1 1 CD cord-005646-xhx9pzhj 893 18 month month NN cord-005646-xhx9pzhj 893 19 to to IN cord-005646-xhx9pzhj 893 20 13 13 CD cord-005646-xhx9pzhj 893 21 years year NNS cord-005646-xhx9pzhj 893 22 , , , cord-005646-xhx9pzhj 893 23 median median JJ cord-005646-xhx9pzhj 893 24 7 7 CD cord-005646-xhx9pzhj 893 25 months month NNS cord-005646-xhx9pzhj 893 26 ) ) -RRB- cord-005646-xhx9pzhj 893 27 with with IN cord-005646-xhx9pzhj 893 28 severe severe JJ cord-005646-xhx9pzhj 893 29 AHRF(18 AHRF(18 NNP cord-005646-xhx9pzhj 893 30 with with IN cord-005646-xhx9pzhj 893 31 ARDS ARDS NNP cord-005646-xhx9pzhj 893 32 ) ) -RRB- cord-005646-xhx9pzhj 893 33 . . . cord-005646-xhx9pzhj 894 1 The the DT cord-005646-xhx9pzhj 894 2 mean mean JJ cord-005646-xhx9pzhj 894 3 P(A P(A NNP cord-005646-xhx9pzhj 894 4 - - HYPH cord-005646-xhx9pzhj 894 5 a)O2 a)O2 NNP cord-005646-xhx9pzhj 894 6 , , , cord-005646-xhx9pzhj 894 7 PaO2 PaO2 NNS cord-005646-xhx9pzhj 894 8 / / SYM cord-005646-xhx9pzhj 894 9 FiO2 FiO2 NNS cord-005646-xhx9pzhj 894 10 , , , cord-005646-xhx9pzhj 894 11 oxygenation oxygenation NN cord-005646-xhx9pzhj 894 12 index index NN cord-005646-xhx9pzhj 894 13 ( ( -LRB- cord-005646-xhx9pzhj 894 14 OI OI NNP cord-005646-xhx9pzhj 894 15 ) ) -RRB- cord-005646-xhx9pzhj 894 16 and and CC cord-005646-xhx9pzhj 894 17 acute acute JJ cord-005646-xhx9pzhj 894 18 lung lung NN cord-005646-xhx9pzhj 894 19 injury injury NN cord-005646-xhx9pzhj 894 20 ( ( -LRB- cord-005646-xhx9pzhj 894 21 ALl all DT cord-005646-xhx9pzhj 894 22 ) ) -RRB- cord-005646-xhx9pzhj 894 23 score score VBP cord-005646-xhx9pzhj 894 24 prior prior RB cord-005646-xhx9pzhj 894 25 to to IN cord-005646-xhx9pzhj 894 26 the the DT cord-005646-xhx9pzhj 894 27 commencement commencement NN cord-005646-xhx9pzhj 894 28 of of IN cord-005646-xhx9pzhj 894 29 iNO iNO NNS cord-005646-xhx9pzhj 894 30 were be VBD cord-005646-xhx9pzhj 894 31 568 568 CD cord-005646-xhx9pzhj 894 32 + + NN cord-005646-xhx9pzhj 894 33 _ _ NN cord-005646-xhx9pzhj 895 1 9.3 9.3 CD cord-005646-xhx9pzhj 895 2 , , , cord-005646-xhx9pzhj 895 3 56 56 CD cord-005646-xhx9pzhj 896 1 + + CC cord-005646-xhx9pzhj 897 1 _ _ NNP cord-005646-xhx9pzhj 897 2 2.3 2.3 CD cord-005646-xhx9pzhj 897 3 , , , cord-005646-xhx9pzhj 897 4 41 41 CD cord-005646-xhx9pzhj 897 5 _ _ NN cord-005646-xhx9pzhj 897 6 +3,8 +3,8 NNP cord-005646-xhx9pzhj 897 7 and and CC cord-005646-xhx9pzhj 897 8 2.8 2.8 CD cord-005646-xhx9pzhj 898 1 + + CC cord-005646-xhx9pzhj 898 2 _ _ NN cord-005646-xhx9pzhj 898 3 0.1 0.1 CD cord-005646-xhx9pzhj 899 1 respectively respectively RB cord-005646-xhx9pzhj 899 2 , , , cord-005646-xhx9pzhj 899 3 The the DT cord-005646-xhx9pzhj 899 4 magnitude magnitude NN cord-005646-xhx9pzhj 899 5 of of IN cord-005646-xhx9pzhj 899 6 response response NN cord-005646-xhx9pzhj 899 7 to to IN cord-005646-xhx9pzhj 899 8 iNO iNO NNS cord-005646-xhx9pzhj 899 9 was be VBD cord-005646-xhx9pzhj 899 10 quantified quantify VBN cord-005646-xhx9pzhj 899 11 as as IN cord-005646-xhx9pzhj 899 12 the the DT cord-005646-xhx9pzhj 899 13 % % NN cord-005646-xhx9pzhj 899 14 change change NN cord-005646-xhx9pzhj 899 15 in in IN cord-005646-xhx9pzhj 899 16 OI OI NNP cord-005646-xhx9pzhj 899 17 occurring occur VBG cord-005646-xhx9pzhj 899 18 within within IN cord-005646-xhx9pzhj 899 19 60 60 CD cord-005646-xhx9pzhj 899 20 minutes minute NNS cord-005646-xhx9pzhj 899 21 of of IN cord-005646-xhx9pzhj 899 22 20 20 CD cord-005646-xhx9pzhj 899 23 ppm ppm NN cord-005646-xhx9pzhj 899 24 iNO iNO NNS cord-005646-xhx9pzhj 899 25 therapy therapy NN cord-005646-xhx9pzhj 899 26 . . . cord-005646-xhx9pzhj 900 1 This this DT cord-005646-xhx9pzhj 900 2 response response NN cord-005646-xhx9pzhj 900 3 was be VBD cord-005646-xhx9pzhj 900 4 compared compare VBN cord-005646-xhx9pzhj 900 5 to to IN cord-005646-xhx9pzhj 900 6 patient patient JJ cord-005646-xhx9pzhj 900 7 outcome outcome NN cord-005646-xhx9pzhj 900 8 data datum NNS cord-005646-xhx9pzhj 900 9 . . . cord-005646-xhx9pzhj 901 1 Results result NNS cord-005646-xhx9pzhj 901 2 . . . cord-005646-xhx9pzhj 902 1 There there EX cord-005646-xhx9pzhj 902 2 was be VBD cord-005646-xhx9pzhj 902 3 a a DT cord-005646-xhx9pzhj 902 4 significant significant JJ cord-005646-xhx9pzhj 902 5 correlation correlation NN cord-005646-xhx9pzhj 902 6 between between IN cord-005646-xhx9pzhj 902 7 response response NN cord-005646-xhx9pzhj 902 8 to to IN cord-005646-xhx9pzhj 902 9 iNO iNO NNS cord-005646-xhx9pzhj 902 10 and and CC cord-005646-xhx9pzhj 902 11 patient patient JJ cord-005646-xhx9pzhj 902 12 outcome outcome NN cord-005646-xhx9pzhj 902 13 , , , cord-005646-xhx9pzhj 902 14 Kendall Kendall NNP cord-005646-xhx9pzhj 902 15 tau tau NNP cord-005646-xhx9pzhj 902 16 B B NNP cord-005646-xhx9pzhj 902 17 r=0,43 r=0,43 NN cord-005646-xhx9pzhj 902 18 , , . cord-005646-xhx9pzhj 903 1 p<0.02 p<0.02 XX cord-005646-xhx9pzhj 903 2 ( ( -LRB- cord-005646-xhx9pzhj 903 3 table table NN cord-005646-xhx9pzhj 903 4 ) ) -RRB- cord-005646-xhx9pzhj 903 5 Conclusion conclusion NN cord-005646-xhx9pzhj 903 6 . . . cord-005646-xhx9pzhj 904 1 In in IN cord-005646-xhx9pzhj 904 2 AHRF AHRF NNP cord-005646-xhx9pzhj 904 3 response response NN cord-005646-xhx9pzhj 904 4 to to IN cord-005646-xhx9pzhj 904 5 iNO iNO NNP cord-005646-xhx9pzhj 904 6 appears appear VBZ cord-005646-xhx9pzhj 904 7 te te NNP cord-005646-xhx9pzhj 904 8 define define VB cord-005646-xhx9pzhj 904 9 a a DT cord-005646-xhx9pzhj 904 10 subgroup subgroup NN cord-005646-xhx9pzhj 904 11 of of IN cord-005646-xhx9pzhj 904 12 patients patient NNS cord-005646-xhx9pzhj 904 13 with with IN cord-005646-xhx9pzhj 904 14 improved improved JJ cord-005646-xhx9pzhj 904 15 outcome outcome NN cord-005646-xhx9pzhj 904 16 compared compare VBN cord-005646-xhx9pzhj 904 17 to to IN cord-005646-xhx9pzhj 904 18 nonresponders nonresponder NNS cord-005646-xhx9pzhj 904 19 . . . cord-005646-xhx9pzhj 905 1 We -PRON- PRP cord-005646-xhx9pzhj 905 2 speculate speculate VBP cord-005646-xhx9pzhj 905 3 that that IN cord-005646-xhx9pzhj 905 4 response response NN cord-005646-xhx9pzhj 905 5 to to IN cord-005646-xhx9pzhj 905 6 iNO iNO NNS cord-005646-xhx9pzhj 905 7 may may MD cord-005646-xhx9pzhj 905 8 be be VB cord-005646-xhx9pzhj 905 9 useful useful JJ cord-005646-xhx9pzhj 905 10 in in IN cord-005646-xhx9pzhj 905 11 selecting select VBG cord-005646-xhx9pzhj 905 12 patients patient NNS cord-005646-xhx9pzhj 905 13 with with IN cord-005646-xhx9pzhj 905 14 potentially potentially RB cord-005646-xhx9pzhj 905 15 reversible reversible JJ cord-005646-xhx9pzhj 905 16 lung lung NN cord-005646-xhx9pzhj 905 17 disease disease NN cord-005646-xhx9pzhj 905 18 for for IN cord-005646-xhx9pzhj 905 19 special special JJ cord-005646-xhx9pzhj 905 20 support support NN cord-005646-xhx9pzhj 905 21 therapies therapy NNS cord-005646-xhx9pzhj 905 22 such such JJ cord-005646-xhx9pzhj 905 23 as as IN cord-005646-xhx9pzhj 905 24 ECMO ECMO NNP cord-005646-xhx9pzhj 905 25 . . . cord-005646-xhx9pzhj 906 1 Randomised randomised JJ cord-005646-xhx9pzhj 906 2 controlled control VBN cord-005646-xhx9pzhj 906 3 trials trial NNS cord-005646-xhx9pzhj 906 4 are be VBP cord-005646-xhx9pzhj 906 5 needed need VBN cord-005646-xhx9pzhj 906 6 to to TO cord-005646-xhx9pzhj 906 7 define define VB cord-005646-xhx9pzhj 906 8 the the DT cord-005646-xhx9pzhj 906 9 role role NN cord-005646-xhx9pzhj 906 10 of of IN cord-005646-xhx9pzhj 906 11 iNO iNO NNS cord-005646-xhx9pzhj 906 12 in in IN cord-005646-xhx9pzhj 906 13 paediatric paediatric JJ cord-005646-xhx9pzhj 906 14 AHRF AHRF NNP cord-005646-xhx9pzhj 906 15 . . . cord-005646-xhx9pzhj 907 1 Between between IN cord-005646-xhx9pzhj 907 2 May May NNP cord-005646-xhx9pzhj 907 3 1994 1994 CD cord-005646-xhx9pzhj 907 4 and and CC cord-005646-xhx9pzhj 907 5 December December NNP cord-005646-xhx9pzhj 907 6 1995 1995 CD cord-005646-xhx9pzhj 907 7 , , , cord-005646-xhx9pzhj 907 8 22 22 CD cord-005646-xhx9pzhj 907 9 patients patient NNS cord-005646-xhx9pzhj 907 10 ( ( -LRB- cord-005646-xhx9pzhj 907 11 pts pt NNS cord-005646-xhx9pzhj 907 12 ) ) -RRB- cord-005646-xhx9pzhj 907 13 were be VBD cord-005646-xhx9pzhj 907 14 treated treat VBN cord-005646-xhx9pzhj 907 15 for for IN cord-005646-xhx9pzhj 907 16 MAS MAS NNP cord-005646-xhx9pzhj 907 17 . . . cord-005646-xhx9pzhj 908 1 Treatment treatment NN cord-005646-xhx9pzhj 908 2 groups group NNS cord-005646-xhx9pzhj 908 3 were be VBD cord-005646-xhx9pzhj 908 4 : : : cord-005646-xhx9pzhj 908 5 group group NN cord-005646-xhx9pzhj 908 6 I -PRON- PRP cord-005646-xhx9pzhj 908 7 only only RB cord-005646-xhx9pzhj 908 8 02:6 02:6 CD cord-005646-xhx9pzhj 908 9 pts pt NNS cord-005646-xhx9pzhj 908 10 ; ; : cord-005646-xhx9pzhj 908 11 group group NN cord-005646-xhx9pzhj 908 12 I1 i1 NN cord-005646-xhx9pzhj 908 13 conventional conventional JJ cord-005646-xhx9pzhj 908 14 mechanioal mechanioal NN cord-005646-xhx9pzhj 908 15 ventilation ventilation NN cord-005646-xhx9pzhj 908 16 ( ( -LRB- cord-005646-xhx9pzhj 908 17 CMV CMV NNP cord-005646-xhx9pzhj 908 18 ) ) -RRB- cord-005646-xhx9pzhj 908 19 : : : cord-005646-xhx9pzhj 908 20 11 11 CD cord-005646-xhx9pzhj 908 21 pts pt NNS cord-005646-xhx9pzhj 908 22 ; ; : cord-005646-xhx9pzhj 908 23 group group NN cord-005646-xhx9pzhj 908 24 II1 II1 NNP cord-005646-xhx9pzhj 908 25 HFO HFO NNP cord-005646-xhx9pzhj 908 26 : : : cord-005646-xhx9pzhj 908 27 1 1 CD cord-005646-xhx9pzhj 908 28 pt pt NN cord-005646-xhx9pzhj 908 29 ; ; : cord-005646-xhx9pzhj 908 30 group group NN cord-005646-xhx9pzhj 908 31 IV IV NNP cord-005646-xhx9pzhj 908 32 HFO+NO HFO+NO NNP cord-005646-xhx9pzhj 908 33 : : : cord-005646-xhx9pzhj 908 34 4 4 CD cord-005646-xhx9pzhj 908 35 pts pt NNS cord-005646-xhx9pzhj 908 36 . . . cord-005646-xhx9pzhj 909 1 Therapy therapy NN cord-005646-xhx9pzhj 909 2 was be VBD cord-005646-xhx9pzhj 909 3 stepwise stepwise RB cord-005646-xhx9pzhj 909 4 intensified intensify VBN cord-005646-xhx9pzhj 909 5 until until IN cord-005646-xhx9pzhj 909 6 oxygenation oxygenation NN cord-005646-xhx9pzhj 909 7 improved improve VBN cord-005646-xhx9pzhj 909 8 ( ( -LRB- cord-005646-xhx9pzhj 909 9 I i NN cord-005646-xhx9pzhj 909 10 - - HYPH cord-005646-xhx9pzhj 909 11 ) ) -RRB- cord-005646-xhx9pzhj 909 12 II II NNP cord-005646-xhx9pzhj 909 13 - - , cord-005646-xhx9pzhj 909 14 ) ) -RRB- cord-005646-xhx9pzhj 909 15 III III NNP cord-005646-xhx9pzhj 909 16 -- -- : cord-005646-xhx9pzhj 909 17 ) ) -RRB- cord-005646-xhx9pzhj 909 18 IV IV NNP cord-005646-xhx9pzhj 909 19 ) ) -RRB- cord-005646-xhx9pzhj 909 20 . . . cord-005646-xhx9pzhj 910 1 " " `` cord-005646-xhx9pzhj 910 2 High high JJ cord-005646-xhx9pzhj 910 3 volume volume NN cord-005646-xhx9pzhj 910 4 strategy strategy NN cord-005646-xhx9pzhj 910 5 " " '' cord-005646-xhx9pzhj 910 6 was be VBD cord-005646-xhx9pzhj 910 7 used use VBN cord-005646-xhx9pzhj 910 8 with with IN cord-005646-xhx9pzhj 910 9 HFO HFO NNP cord-005646-xhx9pzhj 910 10 ( ( -LRB- cord-005646-xhx9pzhj 910 11 MAwP MAwP NNP cord-005646-xhx9pzhj 910 12 18 18 CD cord-005646-xhx9pzhj 910 13 - - SYM cord-005646-xhx9pzhj 910 14 24 24 CD cord-005646-xhx9pzhj 910 15 cm cm NNS cord-005646-xhx9pzhj 910 16 H20 H20 NNP cord-005646-xhx9pzhj 910 17 ) ) -RRB- cord-005646-xhx9pzhj 910 18 . . . cord-005646-xhx9pzhj 911 1 The the DT cord-005646-xhx9pzhj 911 2 initial initial JJ cord-005646-xhx9pzhj 911 3 NO no NN cord-005646-xhx9pzhj 911 4 - - HYPH cord-005646-xhx9pzhj 911 5 concentration concentration NN cord-005646-xhx9pzhj 911 6 was be VBD cord-005646-xhx9pzhj 911 7 20 20 CD cord-005646-xhx9pzhj 911 8 - - SYM cord-005646-xhx9pzhj 911 9 30 30 CD cord-005646-xhx9pzhj 911 10 ppm ppm NN cord-005646-xhx9pzhj 911 11 , , , cord-005646-xhx9pzhj 911 12 with with IN cord-005646-xhx9pzhj 911 13 rapid rapid JJ cord-005646-xhx9pzhj 911 14 reduction reduction NN cord-005646-xhx9pzhj 911 15 down down IN cord-005646-xhx9pzhj 911 16 to to IN cord-005646-xhx9pzhj 911 17 5 5 CD cord-005646-xhx9pzhj 911 18 - - SYM cord-005646-xhx9pzhj 911 19 10 10 CD cord-005646-xhx9pzhj 911 20 ppm ppm NN cord-005646-xhx9pzhj 911 21 once once IN cord-005646-xhx9pzhj 911 22 oxygenation oxygenation NN cord-005646-xhx9pzhj 911 23 improved improve VBD cord-005646-xhx9pzhj 911 24 . . . cord-005646-xhx9pzhj 912 1 Results result NNS cord-005646-xhx9pzhj 912 2 : : : cord-005646-xhx9pzhj 913 1 One one CD cord-005646-xhx9pzhj 913 2 pt pt NN cord-005646-xhx9pzhj 913 3 ( ( -LRB- cord-005646-xhx9pzhj 913 4 group group NN cord-005646-xhx9pzhj 913 5 It -PRON- PRP cord-005646-xhx9pzhj 913 6 ) ) -RRB- cord-005646-xhx9pzhj 913 7 died die VBD cord-005646-xhx9pzhj 913 8 of of IN cord-005646-xhx9pzhj 913 9 hypoxic hypoxic JJ cord-005646-xhx9pzhj 913 10 - - HYPH cord-005646-xhx9pzhj 913 11 ischemic ischemic JJ cord-005646-xhx9pzhj 913 12 encephaiopathy encephaiopathy NNS cord-005646-xhx9pzhj 913 13 ( ( -LRB- cord-005646-xhx9pzhj 913 14 termination termination NN cord-005646-xhx9pzhj 913 15 of of IN cord-005646-xhx9pzhj 913 16 therapy therapy NN cord-005646-xhx9pzhj 913 17 ) ) -RRB- cord-005646-xhx9pzhj 913 18 ; ; : cord-005646-xhx9pzhj 913 19 all all DT cord-005646-xhx9pzhj 913 20 other other JJ cord-005646-xhx9pzhj 913 21 newborn newborn JJ cord-005646-xhx9pzhj 913 22 babies baby NNS cord-005646-xhx9pzhj 913 23 survived survive VBD cord-005646-xhx9pzhj 913 24 . . . cord-005646-xhx9pzhj 914 1 In in IN cord-005646-xhx9pzhj 914 2 group group NN cord-005646-xhx9pzhj 914 3 IV IV NNP cord-005646-xhx9pzhj 914 4 pt pt NN cord-005646-xhx9pzhj 914 5 1 1 CD cord-005646-xhx9pzhj 914 6 and and CC cord-005646-xhx9pzhj 914 7 2 2 CD cord-005646-xhx9pzhj 914 8 showed show VBD cord-005646-xhx9pzhj 914 9 barotrauma barotrauma NN cord-005646-xhx9pzhj 914 10 prior prior RB cord-005646-xhx9pzhj 914 11 to to IN cord-005646-xhx9pzhj 914 12 HFO HFO NNP cord-005646-xhx9pzhj 914 13 . . . cord-005646-xhx9pzhj 915 1 Pt Pt NNP cord-005646-xhx9pzhj 915 2 1,2 1,2 CD cord-005646-xhx9pzhj 915 3 and and CC cord-005646-xhx9pzhj 915 4 4 4 CD cord-005646-xhx9pzhj 915 5 were be VBD cord-005646-xhx9pzhj 915 6 treated treat VBN cord-005646-xhx9pzhj 915 7 with with IN cord-005646-xhx9pzhj 915 8 additional additional JJ cord-005646-xhx9pzhj 915 9 MgCI2 MgCI2 NNP cord-005646-xhx9pzhj 915 10 ( ( -LRB- cord-005646-xhx9pzhj 915 11 max max NNP cord-005646-xhx9pzhj 915 12 . . . cord-005646-xhx9pzhj 916 1 Mg Mg NNP cord-005646-xhx9pzhj 916 2 serum serum NN cord-005646-xhx9pzhj 916 3 concentration concentration NN cord-005646-xhx9pzhj 916 4 2.8 2.8 CD cord-005646-xhx9pzhj 916 5 -6.5 -6.5 NFP cord-005646-xhx9pzhj 916 6 mmol mmol JJ cord-005646-xhx9pzhj 916 7 / / SYM cord-005646-xhx9pzhj 916 8 I i NN cord-005646-xhx9pzhj 916 9 ) ) -RRB- cord-005646-xhx9pzhj 916 10 . . . cord-005646-xhx9pzhj 916 11 _SP cord-005646-xhx9pzhj 917 1 Following follow VBG cord-005646-xhx9pzhj 917 2 the the DT cord-005646-xhx9pzhj 917 3 identification identification NN cord-005646-xhx9pzhj 917 4 of of IN cord-005646-xhx9pzhj 917 5 inhaled inhale VBN cord-005646-xhx9pzhj 917 6 nitric nitric NN cord-005646-xhx9pzhj 917 7 oxide oxide NN cord-005646-xhx9pzhj 917 8 0"NO 0"no CD cord-005646-xhx9pzhj 917 9 ) ) -RRB- cord-005646-xhx9pzhj 917 10 as as IN cord-005646-xhx9pzhj 917 11 a a DT cord-005646-xhx9pzhj 917 12 selective selective JJ cord-005646-xhx9pzhj 917 13 pulmonary pulmonary JJ cord-005646-xhx9pzhj 917 14 vasodilator vasodilator NN cord-005646-xhx9pzhj 917 15 ( ( -LRB- cord-005646-xhx9pzhj 917 16 Frostell Frostell NNP cord-005646-xhx9pzhj 917 17 et et NNP cord-005646-xhx9pzhj 917 18 al al NNP cord-005646-xhx9pzhj 917 19 1992 1992 CD cord-005646-xhx9pzhj 917 20 ) ) -RRB- cord-005646-xhx9pzhj 917 21 [ [ -LRB- cord-005646-xhx9pzhj 917 22 617 617 CD cord-005646-xhx9pzhj 917 23 .+6,3 .+6,3 . cord-005646-xhx9pzhj 918 1 626 626 CD cord-005646-xhx9pzhj 919 1 + + CC cord-005646-xhx9pzhj 920 1 6.3 6.3 CD cord-005646-xhx9pzhj 920 2 Data datum NNS cord-005646-xhx9pzhj 920 3 are be VBP cord-005646-xhx9pzhj 920 4 compared compare VBN cord-005646-xhx9pzhj 920 5 to to IN cord-005646-xhx9pzhj 920 6 baseline baseline JJ cord-005646-xhx9pzhj 920 7 values value NNS cord-005646-xhx9pzhj 920 8 within within IN cord-005646-xhx9pzhj 920 9 each each DT cord-005646-xhx9pzhj 920 10 group group NN cord-005646-xhx9pzhj 920 11 . . . cord-005646-xhx9pzhj 921 1 * * NFP cord-005646-xhx9pzhj 921 2 = = SYM cord-005646-xhx9pzhj 921 3 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 921 4 , , . cord-005646-xhx9pzhj 922 1 * * NFP cord-005646-xhx9pzhj 922 2 * * NFP cord-005646-xhx9pzhj 922 3 = = NFP cord-005646-xhx9pzhj 922 4 p<0.03 p<0.03 XX cord-005646-xhx9pzhj 922 5 , , , cord-005646-xhx9pzhj 923 1 * * NFP cord-005646-xhx9pzhj 923 2 * * NFP cord-005646-xhx9pzhj 923 3 * * NFP cord-005646-xhx9pzhj 923 4 = = NFP cord-005646-xhx9pzhj 923 5 p<0.0l p<0.0l XX cord-005646-xhx9pzhj 924 1 Among among IN cord-005646-xhx9pzhj 924 2 12 12 CD cord-005646-xhx9pzhj 924 3 patients patient NNS cord-005646-xhx9pzhj 924 4 who who WP cord-005646-xhx9pzhj 924 5 fulfilled fulfil VBD cord-005646-xhx9pzhj 924 6 ECMO ECMO NNP cord-005646-xhx9pzhj 924 7 criteria criterion NNS cord-005646-xhx9pzhj 924 8 , , , cord-005646-xhx9pzhj 924 9 6 6 CD cord-005646-xhx9pzhj 924 10 improved improve VBN cord-005646-xhx9pzhj 924 11 with with IN cord-005646-xhx9pzhj 924 12 NO no NN cord-005646-xhx9pzhj 924 13 and and CC cord-005646-xhx9pzhj 924 14 did do VBD cord-005646-xhx9pzhj 924 15 not not RB cord-005646-xhx9pzhj 924 16 required require VBN cord-005646-xhx9pzhj 924 17 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 924 18 life life NN cord-005646-xhx9pzhj 924 19 support support NN cord-005646-xhx9pzhj 924 20 . . . cord-005646-xhx9pzhj 925 1 Tltree Tltree NNP cord-005646-xhx9pzhj 925 2 out out IN cord-005646-xhx9pzhj 925 3 of of IN cord-005646-xhx9pzhj 925 4 6 6 CD cord-005646-xhx9pzhj 925 5 ECMO ECMO NNP cord-005646-xhx9pzhj 925 6 patients patient NNS cord-005646-xhx9pzhj 925 7 eventually eventually RB cord-005646-xhx9pzhj 925 8 survived survive VBD cord-005646-xhx9pzhj 925 9 . . . cord-005646-xhx9pzhj 926 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 926 2 : : : cord-005646-xhx9pzhj 927 1 m m LS cord-005646-xhx9pzhj 927 2 our -PRON- PRP$ cord-005646-xhx9pzhj 927 3 study study NN cord-005646-xhx9pzhj 927 4 low low JJ cord-005646-xhx9pzhj 927 5 - - HYPH cord-005646-xhx9pzhj 927 6 dose dose NN cord-005646-xhx9pzhj 927 7 of of IN cord-005646-xhx9pzhj 927 8 irthaled irthaled JJ cord-005646-xhx9pzhj 927 9 NO NO NNP cord-005646-xhx9pzhj 927 10 showed show VBD cord-005646-xhx9pzhj 927 11 a a DT cord-005646-xhx9pzhj 927 12 variable variable JJ cord-005646-xhx9pzhj 927 13 effect effect NN cord-005646-xhx9pzhj 927 14 on on IN cord-005646-xhx9pzhj 927 15 oxygenation oxygenation NN cord-005646-xhx9pzhj 927 16 in in IN cord-005646-xhx9pzhj 927 17 newborns newborn NNS cord-005646-xhx9pzhj 927 18 with with IN cord-005646-xhx9pzhj 927 19 acute acute JJ cord-005646-xhx9pzhj 927 20 respiratory respiratory JJ cord-005646-xhx9pzhj 927 21 failure failure NN cord-005646-xhx9pzhj 927 22 . . . cord-005646-xhx9pzhj 928 1 An an DT cord-005646-xhx9pzhj 928 2 acute acute JJ cord-005646-xhx9pzhj 928 3 response response NN cord-005646-xhx9pzhj 928 4 to to IN cord-005646-xhx9pzhj 928 5 NO no DT cord-005646-xhx9pzhj 928 6 appeared appear VBD cord-005646-xhx9pzhj 928 7 to to TO cord-005646-xhx9pzhj 928 8 be be VB cord-005646-xhx9pzhj 928 9 correlated correlate VBN cord-005646-xhx9pzhj 928 10 with with IN cord-005646-xhx9pzhj 928 11 a a DT cord-005646-xhx9pzhj 928 12 better well JJR cord-005646-xhx9pzhj 928 13 short short JJ cord-005646-xhx9pzhj 928 14 - - HYPH cord-005646-xhx9pzhj 928 15 term term NN cord-005646-xhx9pzhj 928 16 outcome outcome NN cord-005646-xhx9pzhj 928 17 and and CC cord-005646-xhx9pzhj 928 18 the the DT cord-005646-xhx9pzhj 928 19 avoidance avoidance NN cord-005646-xhx9pzhj 928 20 of of IN cord-005646-xhx9pzhj 928 21 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 928 22 support support NN cord-005646-xhx9pzhj 928 23 in in IN cord-005646-xhx9pzhj 928 24 Ecmo Ecmo NNP cord-005646-xhx9pzhj 928 25 candidates candidate NNS cord-005646-xhx9pzhj 928 26 . . . cord-005646-xhx9pzhj 929 1 Differently differently RB cord-005646-xhx9pzhj 929 2 , , , cord-005646-xhx9pzhj 929 3 lack lack NN cord-005646-xhx9pzhj 929 4 of of IN cord-005646-xhx9pzhj 929 5 acute acute JJ cord-005646-xhx9pzhj 929 6 and/or and/or CC cord-005646-xhx9pzhj 929 7 sustained sustained JJ cord-005646-xhx9pzhj 929 8 response response NN cord-005646-xhx9pzhj 929 9 was be VBD cord-005646-xhx9pzhj 929 10 associated associate VBN cord-005646-xhx9pzhj 929 11 with with IN cord-005646-xhx9pzhj 929 12 death death NN cord-005646-xhx9pzhj 929 13 or or CC cord-005646-xhx9pzhj 929 14 need need NN cord-005646-xhx9pzhj 929 15 for for IN cord-005646-xhx9pzhj 929 16 ECMO ECMO NNP cord-005646-xhx9pzhj 929 17 . . . cord-005646-xhx9pzhj 930 1 Although although IN cord-005646-xhx9pzhj 930 2 the the DT cord-005646-xhx9pzhj 930 3 nature nature NN cord-005646-xhx9pzhj 930 4 and and CC cord-005646-xhx9pzhj 930 5 severity severity NN cord-005646-xhx9pzhj 930 6 of of IN cord-005646-xhx9pzhj 930 7 the the DT cord-005646-xhx9pzhj 930 8 underlying underlie VBG cord-005646-xhx9pzhj 930 9 disease disease NN cord-005646-xhx9pzhj 930 10 or or CC cord-005646-xhx9pzhj 930 11 the the DT cord-005646-xhx9pzhj 930 12 degree degree NN cord-005646-xhx9pzhj 930 13 of of IN cord-005646-xhx9pzhj 930 14 prematurity prematurity NN cord-005646-xhx9pzhj 930 15 may may MD cord-005646-xhx9pzhj 930 16 play play VB cord-005646-xhx9pzhj 930 17 an an DT cord-005646-xhx9pzhj 930 18 important important JJ cord-005646-xhx9pzhj 930 19 role role NN cord-005646-xhx9pzhj 930 20 in in IN cord-005646-xhx9pzhj 930 21 these these DT cord-005646-xhx9pzhj 930 22 patients patient NNS cord-005646-xhx9pzhj 930 23 , , , cord-005646-xhx9pzhj 930 24 we -PRON- PRP cord-005646-xhx9pzhj 930 25 believe believe VBP cord-005646-xhx9pzhj 930 26 lack lack NN cord-005646-xhx9pzhj 930 27 of of IN cord-005646-xhx9pzhj 930 28 acute acute JJ cord-005646-xhx9pzhj 930 29 response response NN cord-005646-xhx9pzhj 930 30 to to IN cord-005646-xhx9pzhj 930 31 NO no DT cord-005646-xhx9pzhj 930 32 may may MD cord-005646-xhx9pzhj 930 33 be be VB cord-005646-xhx9pzhj 930 34 an an DT cord-005646-xhx9pzhj 930 35 early early JJ cord-005646-xhx9pzhj 930 36 predictor predictor NN cord-005646-xhx9pzhj 930 37 of of IN cord-005646-xhx9pzhj 930 38 bad bad JJ cord-005646-xhx9pzhj 930 39 outcome outcome NN cord-005646-xhx9pzhj 930 40 , , , cord-005646-xhx9pzhj 930 41 prompting prompt VBG cord-005646-xhx9pzhj 930 42 toward toward IN cord-005646-xhx9pzhj 930 43 alternative alternative JJ cord-005646-xhx9pzhj 930 44 treatments treatment NNS cord-005646-xhx9pzhj 930 45 such such JJ cord-005646-xhx9pzhj 930 46 as as IN cord-005646-xhx9pzhj 930 47 ECMO ECMO NNP cord-005646-xhx9pzhj 930 48 or or CC cord-005646-xhx9pzhj 930 49 liquid liquid JJ cord-005646-xhx9pzhj 930 50 ventilation ventilation NN cord-005646-xhx9pzhj 930 51 . . . cord-005646-xhx9pzhj 931 1 * * NFP cord-005646-xhx9pzhj 931 2 Picea Picea NNP cord-005646-xhx9pzhj 931 3 S. S. NNP cord-005646-xhx9pzhj 931 4 , , , cord-005646-xhx9pzhj 931 5 ° ° NNP cord-005646-xhx9pzhj 931 6 Bartuli Bartuli NNP cord-005646-xhx9pzhj 931 7 A., a., NN cord-005646-xhx9pzhj 931 8 ° ° VBZ cord-005646-xhx9pzhj 931 9 Dionisi Dionisi NNP cord-005646-xhx9pzhj 931 10 - - HYPH cord-005646-xhx9pzhj 931 11 Vici Vici NNP cord-005646-xhx9pzhj 931 12 C. C. NNP cord-005646-xhx9pzhj 931 13 , , , cord-005646-xhx9pzhj 932 1 * * NFP cord-005646-xhx9pzhj 932 2 Dello Dello NNP cord-005646-xhx9pzhj 932 3 Strologo Strologo NNP cord-005646-xhx9pzhj 932 4 L. L. NNP cord-005646-xhx9pzhj 932 5 , , , cord-005646-xhx9pzhj 933 1 § § NFP cord-005646-xhx9pzhj 933 2 Villani Villani NNP cord-005646-xhx9pzhj 933 3 A. A. NNP cord-005646-xhx9pzhj 933 4 , , , cord-005646-xhx9pzhj 933 5 § § : cord-005646-xhx9pzhj 933 6 Bianchi Bianchi NNP cord-005646-xhx9pzhj 933 7 R. R. NNP cord-005646-xhx9pzhj 933 8 , , , cord-005646-xhx9pzhj 934 1 ^Salvatori ^Salvatori NNP cord-005646-xhx9pzhj 935 1 G.,*Rizzoni G.,*Rizzoni NNP cord-005646-xhx9pzhj 935 2 G G NNP cord-005646-xhx9pzhj 935 3 , , , cord-005646-xhx9pzhj 935 4 ° ° NN cord-005646-xhx9pzhj 935 5 Sabetta Sabetta NNP cord-005646-xhx9pzhj 935 6 G. G. NNP cord-005646-xhx9pzhj 935 7 * * NFP cord-005646-xhx9pzhj 935 8 Div Div NNP cord-005646-xhx9pzhj 935 9 . . . cord-005646-xhx9pzhj 935 10 of of IN cord-005646-xhx9pzhj 935 11 Nephrology Nephrology NNP cord-005646-xhx9pzhj 935 12 , , , cord-005646-xhx9pzhj 935 13 ° ° NN cord-005646-xhx9pzhj 935 14 Div Div NNP cord-005646-xhx9pzhj 935 15 . . . cord-005646-xhx9pzhj 936 1 of of IN cord-005646-xhx9pzhj 936 2 Metabolism metabolism NN cord-005646-xhx9pzhj 936 3 , , , cord-005646-xhx9pzhj 936 4 § § , cord-005646-xhx9pzhj 936 5 Intensive Intensive NNP cord-005646-xhx9pzhj 936 6 Care Care NNP cord-005646-xhx9pzhj 936 7 Unit Unit NNP cord-005646-xhx9pzhj 936 8 , , , cord-005646-xhx9pzhj 936 9 ^Div ^Div NFP cord-005646-xhx9pzhj 936 10 . . . cord-005646-xhx9pzhj 937 1 of of IN cord-005646-xhx9pzhj 937 2 Neonatology Neonatology NNP cord-005646-xhx9pzhj 937 3 . . . cord-005646-xhx9pzhj 938 1 " " '' cord-005646-xhx9pzhj 939 1 Bambino Bambino NNP cord-005646-xhx9pzhj 939 2 Gesfl Gesfl NNP cord-005646-xhx9pzhj 939 3 " " '' cord-005646-xhx9pzhj 939 4 Children Children NNP cord-005646-xhx9pzhj 939 5 Research Research NNP cord-005646-xhx9pzhj 939 6 Hospital Hospital NNP cord-005646-xhx9pzhj 939 7 . . . cord-005646-xhx9pzhj 940 1 ROME ROME NNP cord-005646-xhx9pzhj 940 2 , , , cord-005646-xhx9pzhj 940 3 Italy Italy NNP cord-005646-xhx9pzhj 940 4 . . . cord-005646-xhx9pzhj 941 1 Successful successful JJ cord-005646-xhx9pzhj 941 2 prevention prevention NN cord-005646-xhx9pzhj 941 3 of of IN cord-005646-xhx9pzhj 941 4 handicaps handicap NNS cord-005646-xhx9pzhj 941 5 or or CC cord-005646-xhx9pzhj 941 6 death death NN cord-005646-xhx9pzhj 941 7 in in IN cord-005646-xhx9pzhj 941 8 newborns newborn NNS cord-005646-xhx9pzhj 941 9 with with IN cord-005646-xhx9pzhj 941 10 ~ ~ NFP cord-005646-xhx9pzhj 941 11 depends depend VBZ cord-005646-xhx9pzhj 941 12 on on IN cord-005646-xhx9pzhj 941 13 rapidity rapidity NN cord-005646-xhx9pzhj 941 14 and and CC cord-005646-xhx9pzhj 941 15 efficiency efficiency NN cord-005646-xhx9pzhj 941 16 of of IN cord-005646-xhx9pzhj 941 17 treatment treatment NN cord-005646-xhx9pzhj 941 18 . . . cord-005646-xhx9pzhj 942 1 Poor poor JJ cord-005646-xhx9pzhj 942 2 response response NN cord-005646-xhx9pzhj 942 3 to to IN cord-005646-xhx9pzhj 942 4 nutritional nutritional JJ cord-005646-xhx9pzhj 942 5 and/or and/or CC cord-005646-xhx9pzhj 942 6 pharmacological pharmacological JJ cord-005646-xhx9pzhj 942 7 treatment treatment NN cord-005646-xhx9pzhj 942 8 requires require VBZ cord-005646-xhx9pzhj 942 9 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 942 10 removal removal NN cord-005646-xhx9pzhj 942 11 of of IN cord-005646-xhx9pzhj 942 12 NH4 NH4 NNP cord-005646-xhx9pzhj 942 13 . . . cord-005646-xhx9pzhj 943 1 Efficiency efficiency NN cord-005646-xhx9pzhj 943 2 and and CC cord-005646-xhx9pzhj 943 3 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 943 4 tolerance tolerance NN cord-005646-xhx9pzhj 943 5 are be VBP cord-005646-xhx9pzhj 943 6 often often RB cord-005646-xhx9pzhj 943 7 difficult difficult JJ cord-005646-xhx9pzhj 943 8 to to TO cord-005646-xhx9pzhj 943 9 obtain obtain VB cord-005646-xhx9pzhj 943 10 with with IN cord-005646-xhx9pzhj 943 11 peritoneal peritoneal NN cord-005646-xhx9pzhj 943 12 or or CC cord-005646-xhx9pzhj 943 13 hemodialysis hemodialysis NN cord-005646-xhx9pzhj 943 14 in in IN cord-005646-xhx9pzhj 943 15 neonates neonate NNS cord-005646-xhx9pzhj 943 16 . . . cord-005646-xhx9pzhj 944 1 We -PRON- PRP cord-005646-xhx9pzhj 944 2 report report VBP cord-005646-xhx9pzhj 944 3 the the DT cord-005646-xhx9pzhj 944 4 results result NNS cord-005646-xhx9pzhj 944 5 of of IN cord-005646-xhx9pzhj 944 6 CAVHD cavhd NN cord-005646-xhx9pzhj 944 7 in in IN cord-005646-xhx9pzhj 944 8 3 3 CD cord-005646-xhx9pzhj 944 9 newborns newborn NNS cord-005646-xhx9pzhj 944 10 with with IN cord-005646-xhx9pzhj 944 11 HC HC NNP cord-005646-xhx9pzhj 944 12 . . . cord-005646-xhx9pzhj 945 1 Methods method NNS cord-005646-xhx9pzhj 945 2 : : : cord-005646-xhx9pzhj 945 3 vascular vascular JJ cord-005646-xhx9pzhj 945 4 access access NN cord-005646-xhx9pzhj 945 5 : : : cord-005646-xhx9pzhj 945 6 femoral femoral JJ cord-005646-xhx9pzhj 945 7 vessels vessel NNS cord-005646-xhx9pzhj 945 8 . . . cord-005646-xhx9pzhj 946 1 Blood blood NN cord-005646-xhx9pzhj 946 2 flow flow NN cord-005646-xhx9pzhj 946 3 : : : cord-005646-xhx9pzhj 947 1 10 10 CD cord-005646-xhx9pzhj 947 2 - - SYM cord-005646-xhx9pzhj 947 3 35 35 CD cord-005646-xhx9pzhj 947 4 ml ml NN cord-005646-xhx9pzhj 947 5 / / SYM cord-005646-xhx9pzhj 947 6 min min NN cord-005646-xhx9pzhj 947 7 , , , cord-005646-xhx9pzhj 947 8 Dialysate Dialysate NNP cord-005646-xhx9pzhj 947 9 flow flow NN cord-005646-xhx9pzhj 947 10 : : : cord-005646-xhx9pzhj 947 11 200 200 CD cord-005646-xhx9pzhj 947 12 - - SYM cord-005646-xhx9pzhj 947 13 500 500 CD cord-005646-xhx9pzhj 947 14 ml ml NN cord-005646-xhx9pzhj 947 15 / / SYM cord-005646-xhx9pzhj 947 16 h h NN cord-005646-xhx9pzhj 947 17 . . . cord-005646-xhx9pzhj 948 1 Filter filter NN cord-005646-xhx9pzhj 948 2 : : : cord-005646-xhx9pzhj 948 3 Amicon Amicon NNP cord-005646-xhx9pzhj 948 4 Minifilter Minifilter NNP cord-005646-xhx9pzhj 948 5 PlusrM(polysulfone plusrm(polysulfone JJ cord-005646-xhx9pzhj 948 6 membrane membrane NN cord-005646-xhx9pzhj 948 7 ; ; : cord-005646-xhx9pzhj 948 8 0.08 0.08 CD cord-005646-xhx9pzhj 948 9 sq.m sq.m NNS cord-005646-xhx9pzhj 948 10 . . . cord-005646-xhx9pzhj 948 11 ) ) -RRB- cord-005646-xhx9pzhj 948 12 . . . cord-005646-xhx9pzhj 949 1 No no DT cord-005646-xhx9pzhj 949 2 ultrafiltrate(UF ultrafiltrate(uf NN cord-005646-xhx9pzhj 949 3 ) ) -RRB- cord-005646-xhx9pzhj 949 4 production production NN cord-005646-xhx9pzhj 949 5 , , , cord-005646-xhx9pzhj 949 6 Patients patient NNS cord-005646-xhx9pzhj 949 7 : : : cord-005646-xhx9pzhj 949 8 Case case NN cord-005646-xhx9pzhj 949 9 1 1 CD cord-005646-xhx9pzhj 949 10 with with IN cord-005646-xhx9pzhj 949 11 carbamoytphosphate carbamoytphosphate NNP cord-005646-xhx9pzhj 949 12 synthetase synthetase NNP cord-005646-xhx9pzhj 949 13 deficiency deficiency NN cord-005646-xhx9pzhj 949 14 ( ( -LRB- cord-005646-xhx9pzhj 949 15 body body NN cord-005646-xhx9pzhj 949 16 weight weight NN cord-005646-xhx9pzhj 949 17 -bw- -bw- : cord-005646-xhx9pzhj 949 18 : : : cord-005646-xhx9pzhj 949 19 3.2 3.2 CD cord-005646-xhx9pzhj 949 20 kg kg NNS cord-005646-xhx9pzhj 949 21 ) ) -RRB- cord-005646-xhx9pzhj 949 22 showed show VBD cord-005646-xhx9pzhj 949 23 HC HC NNP cord-005646-xhx9pzhj 949 24 at at IN cord-005646-xhx9pzhj 949 25 day day NN cord-005646-xhx9pzhj 949 26 4 4 CD cord-005646-xhx9pzhj 949 27 , , , cord-005646-xhx9pzhj 949 28 A a DT cord-005646-xhx9pzhj 949 29 relapse relapse NN cord-005646-xhx9pzhj 949 30 of of IN cord-005646-xhx9pzhj 949 31 HC HC NNP cord-005646-xhx9pzhj 949 32 occurred occur VBD cord-005646-xhx9pzhj 949 33 at at IN cord-005646-xhx9pzhj 949 34 day day NN cord-005646-xhx9pzhj 949 35 14 14 CD cord-005646-xhx9pzhj 949 36 due due IN cord-005646-xhx9pzhj 949 37 to to IN cord-005646-xhx9pzhj 949 38 an an DT cord-005646-xhx9pzhj 949 39 infectious infectious JJ cord-005646-xhx9pzhj 949 40 event event NN cord-005646-xhx9pzhj 949 41 . . . cord-005646-xhx9pzhj 950 1 Case case NN cord-005646-xhx9pzhj 950 2 2 2 CD cord-005646-xhx9pzhj 950 3 and and CC cord-005646-xhx9pzhj 950 4 3 3 CD cord-005646-xhx9pzhj 951 1 ( ( -LRB- cord-005646-xhx9pzhj 951 2 bw bw NNP cord-005646-xhx9pzhj 951 3 : : : cord-005646-xhx9pzhj 951 4 3.0 3.0 CD cord-005646-xhx9pzhj 951 5 and and CC cord-005646-xhx9pzhj 951 6 2.8 2.8 CD cord-005646-xhx9pzhj 951 7 kg kg NNS cord-005646-xhx9pzhj 951 8 ) ) -RRB- cord-005646-xhx9pzhj 951 9 , , , cord-005646-xhx9pzhj 951 10 both both DT cord-005646-xhx9pzhj 951 11 affected affect VBN cord-005646-xhx9pzhj 951 12 by by IN cord-005646-xhx9pzhj 951 13 propionic propionic NN cord-005646-xhx9pzhj 951 14 aeidemia aeidemia NNP cord-005646-xhx9pzhj 951 15 , , , cord-005646-xhx9pzhj 951 16 showed show VBD cord-005646-xhx9pzhj 951 17 HC HC NNP cord-005646-xhx9pzhj 951 18 at at IN cord-005646-xhx9pzhj 951 19 day day NN cord-005646-xhx9pzhj 951 20 5 5 CD cord-005646-xhx9pzhj 951 21 and and CC cord-005646-xhx9pzhj 951 22 day day NN cord-005646-xhx9pzhj 951 23 7 7 CD cord-005646-xhx9pzhj 951 24 , , , cord-005646-xhx9pzhj 951 25 respectively respectively RB cord-005646-xhx9pzhj 951 26 . . . cord-005646-xhx9pzhj 952 1 Plasma plasma NN cord-005646-xhx9pzhj 952 2 NH4 NH4 NNP cord-005646-xhx9pzhj 952 3 ( ( -LRB- cord-005646-xhx9pzhj 952 4 ~tg ~tg NNP cord-005646-xhx9pzhj 952 5 / / SYM cord-005646-xhx9pzhj 952 6 dl dl NN cord-005646-xhx9pzhj 952 7 ) ) -RRB- cord-005646-xhx9pzhj 952 8 decrease decrease NN cord-005646-xhx9pzhj 952 9 is be VBZ cord-005646-xhx9pzhj 952 10 shown show VBN cord-005646-xhx9pzhj 952 11 in in IN cord-005646-xhx9pzhj 952 12 the the DT cord-005646-xhx9pzhj 952 13 Complications complication NNS cord-005646-xhx9pzhj 952 14 : : : cord-005646-xhx9pzhj 952 15 transitory transitory JJ cord-005646-xhx9pzhj 952 16 ischemia ischemia NN cord-005646-xhx9pzhj 952 17 of of IN cord-005646-xhx9pzhj 952 18 arterial arterial JJ cord-005646-xhx9pzhj 952 19 cannulation cannulation NN cord-005646-xhx9pzhj 952 20 limb limb NN cord-005646-xhx9pzhj 952 21 and and CC cord-005646-xhx9pzhj 952 22 transitory transitory JJ cord-005646-xhx9pzhj 952 23 thrombocytopenia thrombocytopenia NN cord-005646-xhx9pzhj 952 24 occurred occur VBD cord-005646-xhx9pzhj 952 25 in in IN cord-005646-xhx9pzhj 952 26 case case NN cord-005646-xhx9pzhj 952 27 1 1 CD cord-005646-xhx9pzhj 952 28 ; ; , cord-005646-xhx9pzhj 952 29 surgical surgical JJ cord-005646-xhx9pzhj 952 30 repairing repairing NN cord-005646-xhx9pzhj 952 31 of of IN cord-005646-xhx9pzhj 952 32 artery artery NN cord-005646-xhx9pzhj 952 33 after after IN cord-005646-xhx9pzhj 952 34 CAVt CAVt NNS cord-005646-xhx9pzhj 952 35 - - : cord-005646-xhx9pzhj 952 36 ID ID NNP cord-005646-xhx9pzhj 952 37 was be VBD cord-005646-xhx9pzhj 952 38 necessary necessary JJ cord-005646-xhx9pzhj 952 39 in in IN cord-005646-xhx9pzhj 952 40 case case NN cord-005646-xhx9pzhj 952 41 3 3 CD cord-005646-xhx9pzhj 952 42 ; ; : cord-005646-xhx9pzhj 952 43 no no DT cord-005646-xhx9pzhj 952 44 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 952 45 instability instability NN cord-005646-xhx9pzhj 952 46 was be VBD cord-005646-xhx9pzhj 952 47 observed observe VBN cord-005646-xhx9pzhj 952 48 during during IN cord-005646-xhx9pzhj 952 49 CAVHD CAVHD NNP cord-005646-xhx9pzhj 952 50 . . . cord-005646-xhx9pzhj 953 1 Outcome,'all Outcome,'all NNP cord-005646-xhx9pzhj 953 2 patients patient NNS cord-005646-xhx9pzhj 953 3 recovered recover VBD cord-005646-xhx9pzhj 953 4 from from IN cord-005646-xhx9pzhj 953 5 HC HC NNP cord-005646-xhx9pzhj 953 6 in in IN cord-005646-xhx9pzhj 953 7 less less JJR cord-005646-xhx9pzhj 953 8 than than IN cord-005646-xhx9pzhj 953 9 1 1 CD cord-005646-xhx9pzhj 953 10 day day NN cord-005646-xhx9pzhj 953 11 : : : cord-005646-xhx9pzhj 953 12 case case NN cord-005646-xhx9pzhj 953 13 1 1 CD cord-005646-xhx9pzhj 953 14 : : : cord-005646-xhx9pzhj 953 15 alive alive JJ cord-005646-xhx9pzhj 953 16 , , , cord-005646-xhx9pzhj 953 17 mild mild JJ cord-005646-xhx9pzhj 953 18 b)Iootonia b)Iootonia NNP cord-005646-xhx9pzhj 953 19 at at IN cord-005646-xhx9pzhj 953 20 34 34 CD cord-005646-xhx9pzhj 953 21 mos mos NN cord-005646-xhx9pzhj 953 22 ; ; : cord-005646-xhx9pzhj 953 23 case case NN cord-005646-xhx9pzhj 953 24 2 2 CD cord-005646-xhx9pzhj 953 25 : : : cord-005646-xhx9pzhj 953 26 dead dead JJ cord-005646-xhx9pzhj 953 27 after after IN cord-005646-xhx9pzhj 953 28 10 10 CD cord-005646-xhx9pzhj 953 29 days day NNS cord-005646-xhx9pzhj 953 30 from from IN cord-005646-xhx9pzhj 953 31 CAVHD cavhd NN cord-005646-xhx9pzhj 953 32 withdrawal withdrawal NN cord-005646-xhx9pzhj 953 33 for for IN cord-005646-xhx9pzhj 953 34 pulmonary pulmonary JJ cord-005646-xhx9pzhj 953 35 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 953 36 ; ; : cord-005646-xhx9pzhj 953 37 case case NN cord-005646-xhx9pzhj 953 38 3 3 CD cord-005646-xhx9pzhj 953 39 : : : cord-005646-xhx9pzhj 953 40 alive alive JJ cord-005646-xhx9pzhj 953 41 , , , cord-005646-xhx9pzhj 953 42 normal normal JJ cord-005646-xhx9pzhj 953 43 development development NN cord-005646-xhx9pzhj 953 44 at at IN cord-005646-xhx9pzhj 953 45 7 7 CD cord-005646-xhx9pzhj 953 46 mos mos NN cord-005646-xhx9pzhj 953 47 . . . cord-005646-xhx9pzhj 954 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 954 2 : : : cord-005646-xhx9pzhj 954 3 1 1 LS cord-005646-xhx9pzhj 954 4 ) ) -RRB- cord-005646-xhx9pzhj 955 1 In in IN cord-005646-xhx9pzhj 955 2 newborns newborn NNS cord-005646-xhx9pzhj 955 3 with with IN cord-005646-xhx9pzhj 955 4 HC HC NNP cord-005646-xhx9pzhj 955 5 , , , cord-005646-xhx9pzhj 955 6 CA CA NNP cord-005646-xhx9pzhj 955 7 ~ ~ NNP cord-005646-xhx9pzhj 955 8 q q NNP cord-005646-xhx9pzhj 955 9 - - HYPH cord-005646-xhx9pzhj 955 10 ID ID NNP cord-005646-xhx9pzhj 955 11 provides provide VBZ cord-005646-xhx9pzhj 955 12 good good JJ cord-005646-xhx9pzhj 955 13 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 955 14 tolerance tolerance NN cord-005646-xhx9pzhj 955 15 , , , cord-005646-xhx9pzhj 955 16 high high JJ cord-005646-xhx9pzhj 955 17 efficiency efficiency NN cord-005646-xhx9pzhj 955 18 and and CC cord-005646-xhx9pzhj 955 19 quick quick JJ cord-005646-xhx9pzhj 955 20 removal removal NN cord-005646-xhx9pzhj 955 21 of of IN cord-005646-xhx9pzhj 955 22 NH4 NH4 NNP cord-005646-xhx9pzhj 955 23 , , , cord-005646-xhx9pzhj 955 24 even even RB cord-005646-xhx9pzhj 955 25 without without IN cord-005646-xhx9pzhj 955 26 UF UF NNP cord-005646-xhx9pzhj 955 27 production production NN cord-005646-xhx9pzhj 955 28 ( ( -LRB- cord-005646-xhx9pzhj 955 29 i.e. i.e. FW cord-005646-xhx9pzhj 955 30 only only RB cord-005646-xhx9pzhj 955 31 by by IN cord-005646-xhx9pzhj 955 32 diffusion diffusion NN cord-005646-xhx9pzhj 955 33 ) ) -RRB- cord-005646-xhx9pzhj 955 34 . . . cord-005646-xhx9pzhj 956 1 This this DT cord-005646-xhx9pzhj 956 2 allows allow VBZ cord-005646-xhx9pzhj 956 3 easier easy JJR cord-005646-xhx9pzhj 956 4 management management NN cord-005646-xhx9pzhj 956 5 ( ( -LRB- cord-005646-xhx9pzhj 956 6 no no DT cord-005646-xhx9pzhj 956 7 need need NN cord-005646-xhx9pzhj 956 8 of of IN cord-005646-xhx9pzhj 956 9 fluid fluid JJ cord-005646-xhx9pzhj 956 10 and and CC cord-005646-xhx9pzhj 956 11 electrolyte electrolyte JJ cord-005646-xhx9pzhj 956 12 balance balance NN cord-005646-xhx9pzhj 956 13 ) ) -RRB- cord-005646-xhx9pzhj 956 14 . . . cord-005646-xhx9pzhj 957 1 2 2 LS cord-005646-xhx9pzhj 957 2 ) ) -RRB- cord-005646-xhx9pzhj 958 1 Arterial arterial JJ cord-005646-xhx9pzhj 958 2 complications complication NNS cord-005646-xhx9pzhj 958 3 seem seem VBP cord-005646-xhx9pzhj 958 4 frequent frequent JJ cord-005646-xhx9pzhj 958 5 in in IN cord-005646-xhx9pzhj 958 6 neonates neonate NNS cord-005646-xhx9pzhj 958 7 treated treat VBN cord-005646-xhx9pzhj 958 8 by by IN cord-005646-xhx9pzhj 958 9 CAVHD CAVHD NNP cord-005646-xhx9pzhj 958 10 . . . cord-005646-xhx9pzhj 959 1 Venovenous venovenous JJ cord-005646-xhx9pzhj 959 2 circulation circulation NN cord-005646-xhx9pzhj 959 3 could could MD cord-005646-xhx9pzhj 959 4 overcome overcome VB cord-005646-xhx9pzhj 959 5 this this DT cord-005646-xhx9pzhj 959 6 problem problem NN cord-005646-xhx9pzhj 959 7 . . . cord-005646-xhx9pzhj 960 1 VB VB NNP cord-005646-xhx9pzhj 960 2 Nguyen Nguyen NNP cord-005646-xhx9pzhj 960 3 , , , cord-005646-xhx9pzhj 960 4 M M NNP cord-005646-xhx9pzhj 960 5 Jokie Jokie NNP cord-005646-xhx9pzhj 960 6 , , , cord-005646-xhx9pzhj 960 7 C C NNP cord-005646-xhx9pzhj 960 8 Leeaeheux Leeaeheux NNP cord-005646-xhx9pzhj 960 9 Paediatric Paediatric NNP cord-005646-xhx9pzhj 960 10 Intensive Intensive NNP cord-005646-xhx9pzhj 960 11 Case Case NNP cord-005646-xhx9pzhj 960 12 Service Service NNP cord-005646-xhx9pzhj 960 13 , , , cord-005646-xhx9pzhj 960 14 Hospital Hospital NNP cord-005646-xhx9pzhj 960 15 University University NNP cord-005646-xhx9pzhj 960 16 Centre Centre NNP cord-005646-xhx9pzhj 960 17 , , , cord-005646-xhx9pzhj 960 18 Avenue Avenue NNP cord-005646-xhx9pzhj 960 19 C6te C6te NNP cord-005646-xhx9pzhj 960 20 de de NNP cord-005646-xhx9pzhj 960 21 Nacre Nacre NNP cord-005646-xhx9pzhj 960 22 , , , cord-005646-xhx9pzhj 960 23 14033 14033 CD cord-005646-xhx9pzhj 960 24 Caen Caen NNP cord-005646-xhx9pzhj 960 25 Cedex Cedex NNP cord-005646-xhx9pzhj 960 26 , , , cord-005646-xhx9pzhj 960 27 France France NNP cord-005646-xhx9pzhj 960 28 Background Background NNP cord-005646-xhx9pzhj 960 29 , , , cord-005646-xhx9pzhj 960 30 The the DT cord-005646-xhx9pzhj 960 31 implication implication NN cord-005646-xhx9pzhj 960 32 of of IN cord-005646-xhx9pzhj 960 33 polymorphonuclear polymorphonuclear JJ cord-005646-xhx9pzhj 960 34 neutrophils neutrophil NNS cord-005646-xhx9pzhj 960 35 ( ( -LRB- cord-005646-xhx9pzhj 960 36 PMNs PMNs NNP cord-005646-xhx9pzhj 960 37 ) ) -RRB- cord-005646-xhx9pzhj 960 38 in in IN cord-005646-xhx9pzhj 960 39 the the DT cord-005646-xhx9pzhj 960 40 physiopathology physiopathology NN cord-005646-xhx9pzhj 960 41 of of IN cord-005646-xhx9pzhj 960 42 children child NNS cord-005646-xhx9pzhj 960 43 's 's POS cord-005646-xhx9pzhj 960 44 haemolytic.uraemie haemolytic.uraemie NNP cord-005646-xhx9pzhj 960 45 syndrome syndrome NN cord-005646-xhx9pzhj 960 46 ( ( -LRB- cord-005646-xhx9pzhj 960 47 HUS HUS NNP cord-005646-xhx9pzhj 960 48 ) ) -RRB- cord-005646-xhx9pzhj 960 49 becomes become VBZ cord-005646-xhx9pzhj 960 50 more more RBR cord-005646-xhx9pzhj 960 51 and and CC cord-005646-xhx9pzhj 960 52 more more RBR cord-005646-xhx9pzhj 960 53 evident evident JJ cord-005646-xhx9pzhj 960 54 . . . cord-005646-xhx9pzhj 961 1 The the DT cord-005646-xhx9pzhj 961 2 purpose purpose NN cord-005646-xhx9pzhj 961 3 of of IN cord-005646-xhx9pzhj 961 4 the the DT cord-005646-xhx9pzhj 961 5 present present JJ cord-005646-xhx9pzhj 961 6 study study NN cord-005646-xhx9pzhj 961 7 is be VBZ cord-005646-xhx9pzhj 961 8 to to TO cord-005646-xhx9pzhj 961 9 role role VB cord-005646-xhx9pzhj 961 10 out out RP cord-005646-xhx9pzhj 961 11 their -PRON- PRP$ cord-005646-xhx9pzhj 961 12 impact impact NN cord-005646-xhx9pzhj 961 13 among among IN cord-005646-xhx9pzhj 961 14 other other JJ cord-005646-xhx9pzhj 961 15 pronostie pronostie NN cord-005646-xhx9pzhj 961 16 elements element NNS cord-005646-xhx9pzhj 961 17 during during IN cord-005646-xhx9pzhj 961 18 the the DT cord-005646-xhx9pzhj 961 19 course course NN cord-005646-xhx9pzhj 961 20 of of IN cord-005646-xhx9pzhj 961 21 the the DT cord-005646-xhx9pzhj 961 22 disease disease NN cord-005646-xhx9pzhj 961 23 . . . cord-005646-xhx9pzhj 962 1 Patients patient NNS cord-005646-xhx9pzhj 962 2 and and CC cord-005646-xhx9pzhj 962 3 methods method NNS cord-005646-xhx9pzhj 962 4 . . . cord-005646-xhx9pzhj 963 1 Diarrheal diarrheal JJ cord-005646-xhx9pzhj 963 2 prodrome prodrome NN cord-005646-xhx9pzhj 963 3 and and CC cord-005646-xhx9pzhj 963 4 its -PRON- PRP$ cord-005646-xhx9pzhj 963 5 duration duration NN cord-005646-xhx9pzhj 963 6 , , , cord-005646-xhx9pzhj 963 7 patient patient NN cord-005646-xhx9pzhj 963 8 's 's POS cord-005646-xhx9pzhj 963 9 age age NN cord-005646-xhx9pzhj 963 10 , , , cord-005646-xhx9pzhj 963 11 maximal maximal JJ cord-005646-xhx9pzhj 963 12 blood blood NN cord-005646-xhx9pzhj 963 13 nitrogen nitrogen NN cord-005646-xhx9pzhj 963 14 level level NN cord-005646-xhx9pzhj 963 15 , , , cord-005646-xhx9pzhj 963 16 anuria anuria NN cord-005646-xhx9pzhj 963 17 and and CC cord-005646-xhx9pzhj 963 18 dialysis dialysis NN cord-005646-xhx9pzhj 963 19 time time NN cord-005646-xhx9pzhj 963 20 , , , cord-005646-xhx9pzhj 963 21 extra.renal extra.renal JJ cord-005646-xhx9pzhj 963 22 involvements involvement NNS cord-005646-xhx9pzhj 963 23 , , , cord-005646-xhx9pzhj 963 24 white white JJ cord-005646-xhx9pzhj 963 25 enll enll NNP cord-005646-xhx9pzhj 963 26 and and CC cord-005646-xhx9pzhj 963 27 PMN PMN NNP cord-005646-xhx9pzhj 963 28 counts count VBZ cord-005646-xhx9pzhj 963 29 and and CC cord-005646-xhx9pzhj 963 30 thrombopenia thrombopenia NNP cord-005646-xhx9pzhj 963 31 duration duration NN cord-005646-xhx9pzhj 963 32 have have VBP cord-005646-xhx9pzhj 963 33 been be VBN cord-005646-xhx9pzhj 963 34 retrospectively retrospectively RB cord-005646-xhx9pzhj 963 35 analysed analyse VBN cord-005646-xhx9pzhj 963 36 in in IN cord-005646-xhx9pzhj 963 37 18 18 CD cord-005646-xhx9pzhj 963 38 infants infant NNS cord-005646-xhx9pzhj 963 39 with with IN cord-005646-xhx9pzhj 963 40 good good JJ cord-005646-xhx9pzhj 963 41 outcome outcome NN cord-005646-xhx9pzhj 963 42 and and CC cord-005646-xhx9pzhj 963 43 in in IN cord-005646-xhx9pzhj 963 44 8 8 CD cord-005646-xhx9pzhj 963 45 another another DT cord-005646-xhx9pzhj 963 46 children child NNS cord-005646-xhx9pzhj 963 47 with with IN cord-005646-xhx9pzhj 963 48 unfavorable unfavorable JJ cord-005646-xhx9pzhj 963 49 outcome outcome NN cord-005646-xhx9pzhj 963 50 . . . cord-005646-xhx9pzhj 964 1 Results result NNS cord-005646-xhx9pzhj 964 2 . . . cord-005646-xhx9pzhj 965 1 Neither neither DT cord-005646-xhx9pzhj 965 2 diarrhoea diarrhoea NN cord-005646-xhx9pzhj 965 3 or or CC cord-005646-xhx9pzhj 965 4 its -PRON- PRP$ cord-005646-xhx9pzhj 965 5 duration duration NN cord-005646-xhx9pzhj 965 6 , , , cord-005646-xhx9pzhj 965 7 nor nor CC cord-005646-xhx9pzhj 965 8 children child NNS cord-005646-xhx9pzhj 965 9 's 's POS cord-005646-xhx9pzhj 965 10 age age NN cord-005646-xhx9pzhj 965 11 , , , cord-005646-xhx9pzhj 965 12 nor nor CC cord-005646-xhx9pzhj 965 13 blood blood NN cord-005646-xhx9pzhj 965 14 nitrogen nitrogen NN cord-005646-xhx9pzhj 965 15 level level NN cord-005646-xhx9pzhj 965 16 , , , cord-005646-xhx9pzhj 965 17 nor nor CC cord-005646-xhx9pzhj 965 18 anuria anuria NN cord-005646-xhx9pzhj 965 19 or or CC cord-005646-xhx9pzhj 965 20 dialysis dialysis NN cord-005646-xhx9pzhj 965 21 time time NN cord-005646-xhx9pzhj 965 22 had have VBD cord-005646-xhx9pzhj 965 23 any any DT cord-005646-xhx9pzhj 965 24 predictive predictive JJ cord-005646-xhx9pzhj 965 25 value value NN cord-005646-xhx9pzhj 965 26 for for IN cord-005646-xhx9pzhj 965 27 the the DT cord-005646-xhx9pzhj 965 28 disease disease NN cord-005646-xhx9pzhj 965 29 evolution evolution NN cord-005646-xhx9pzhj 965 30 in in IN cord-005646-xhx9pzhj 965 31 the the DT cord-005646-xhx9pzhj 965 32 acute acute JJ cord-005646-xhx9pzhj 965 33 phase phase NN cord-005646-xhx9pzhj 965 34 of of IN cord-005646-xhx9pzhj 965 35 our -PRON- PRP$ cord-005646-xhx9pzhj 965 36 patients patient NNS cord-005646-xhx9pzhj 965 37 . . . cord-005646-xhx9pzhj 966 1 Adversely adversely RB cord-005646-xhx9pzhj 966 2 , , , cord-005646-xhx9pzhj 966 3 extra extra JJ cord-005646-xhx9pzhj 966 4 - - JJ cord-005646-xhx9pzhj 966 5 nenal nenal JJ cord-005646-xhx9pzhj 966 6 involvements involvement NNS cord-005646-xhx9pzhj 966 7 was be VBD cord-005646-xhx9pzhj 966 8 accompanied accompany VBN cord-005646-xhx9pzhj 966 9 by by IN cord-005646-xhx9pzhj 966 10 severe severe JJ cord-005646-xhx9pzhj 966 11 and and CC cord-005646-xhx9pzhj 966 12 complicated complicated JJ cord-005646-xhx9pzhj 966 13 courses course NNS cord-005646-xhx9pzhj 966 14 of of IN cord-005646-xhx9pzhj 966 15 the the DT cord-005646-xhx9pzhj 966 16 disease disease NN cord-005646-xhx9pzhj 966 17 ( ( -LRB- cord-005646-xhx9pzhj 966 18 p<0,02 p<0,02 NNP cord-005646-xhx9pzhj 966 19 ) ) -RRB- cord-005646-xhx9pzhj 966 20 . . . cord-005646-xhx9pzhj 967 1 The the DT cord-005646-xhx9pzhj 967 2 elevation elevation NN cord-005646-xhx9pzhj 967 3 of of IN cord-005646-xhx9pzhj 967 4 white white JJ cord-005646-xhx9pzhj 967 5 cells cell NNS cord-005646-xhx9pzhj 967 6 and and CC cord-005646-xhx9pzhj 967 7 PMNs pmn NNS cord-005646-xhx9pzhj 967 8 ( ( -LRB- cord-005646-xhx9pzhj 967 9 heyon heyon NNP cord-005646-xhx9pzhj 967 10 20 20 CD cord-005646-xhx9pzhj 967 11 x x SYM cord-005646-xhx9pzhj 967 12 109 109 CD cord-005646-xhx9pzhj 967 13 / / SYM cord-005646-xhx9pzhj 967 14 i i NN cord-005646-xhx9pzhj 967 15 ) ) -RRB- cord-005646-xhx9pzhj 967 16 and and CC cord-005646-xhx9pzhj 967 17 PMNs PMNs NNP cord-005646-xhx9pzhj 967 18 ( ( -LRB- cord-005646-xhx9pzhj 967 19 more more JJR cord-005646-xhx9pzhj 967 20 than than IN cord-005646-xhx9pzhj 967 21 15 15 CD cord-005646-xhx9pzhj 967 22 x x SYM cord-005646-xhx9pzhj 967 23 109/1 109/1 CD cord-005646-xhx9pzhj 967 24 ) ) -RRB- cord-005646-xhx9pzhj 967 25 as as RB cord-005646-xhx9pzhj 967 26 well well RB cord-005646-xhx9pzhj 967 27 as as IN cord-005646-xhx9pzhj 967 28 its -PRON- PRP$ cord-005646-xhx9pzhj 967 29 persistence persistence NN cord-005646-xhx9pzhj 967 30 beyon beyon RB cord-005646-xhx9pzhj 967 31 a a DT cord-005646-xhx9pzhj 967 32 week week NN cord-005646-xhx9pzhj 967 33 were be VBD cord-005646-xhx9pzhj 967 34 most most RBS cord-005646-xhx9pzhj 967 35 frequently frequently RB cord-005646-xhx9pzhj 967 36 observed observe VBN cord-005646-xhx9pzhj 967 37 in in IN cord-005646-xhx9pzhj 967 38 complicated complicated JJ cord-005646-xhx9pzhj 967 39 forms form NNS cord-005646-xhx9pzhj 967 40 ( ( -LRB- cord-005646-xhx9pzhj 967 41 p<0,001 p<0,001 NNP cord-005646-xhx9pzhj 967 42 , , , cord-005646-xhx9pzhj 967 43 p<0,001 p<0,001 NNP cord-005646-xhx9pzhj 967 44 and and CC cord-005646-xhx9pzhj 967 45 p<0,01 p<0,01 NN cord-005646-xhx9pzhj 967 46 , , , cord-005646-xhx9pzhj 967 47 respectively respectively RB cord-005646-xhx9pzhj 967 48 ) ) -RRB- cord-005646-xhx9pzhj 967 49 . . . cord-005646-xhx9pzhj 968 1 A a DT cord-005646-xhx9pzhj 968 2 transient transient JJ cord-005646-xhx9pzhj 968 3 thrombopenia thrombopenia NN cord-005646-xhx9pzhj 968 4 ( ( -LRB- cord-005646-xhx9pzhj 968 5 less less JJR cord-005646-xhx9pzhj 968 6 than than IN cord-005646-xhx9pzhj 968 7 5 5 CD cord-005646-xhx9pzhj 968 8 day@ day@ NNS cord-005646-xhx9pzhj 968 9 in in IN cord-005646-xhx9pzhj 968 10 patients patient NNS cord-005646-xhx9pzhj 968 11 with with IN cord-005646-xhx9pzhj 968 12 elevated elevated JJ cord-005646-xhx9pzhj 968 13 counts count NNS cord-005646-xhx9pzhj 968 14 of of IN cord-005646-xhx9pzhj 968 15 white white JJ cord-005646-xhx9pzhj 968 16 cells cell NNS cord-005646-xhx9pzhj 968 17 may may MD cord-005646-xhx9pzhj 968 18 be be VB cord-005646-xhx9pzhj 968 19 a a DT cord-005646-xhx9pzhj 968 20 filrther filrther JJ cord-005646-xhx9pzhj 968 21 obvious obvious JJ cord-005646-xhx9pzhj 968 22 sign sign NN cord-005646-xhx9pzhj 968 23 of of IN cord-005646-xhx9pzhj 968 24 an an DT cord-005646-xhx9pzhj 968 25 unfavorable unfavorable JJ cord-005646-xhx9pzhj 968 26 course course NN cord-005646-xhx9pzhj 968 27 of of IN cord-005646-xhx9pzhj 968 28 the the DT cord-005646-xhx9pzhj 968 29 disease disease NN cord-005646-xhx9pzhj 968 30 ( ( -LRB- cord-005646-xhx9pzhj 968 31 13<0,02 13<0,02 CD cord-005646-xhx9pzhj 968 32 ) ) -RRB- cord-005646-xhx9pzhj 968 33 . . . cord-005646-xhx9pzhj 969 1 Conclusion conclusion NN cord-005646-xhx9pzhj 969 2 . . . cord-005646-xhx9pzhj 970 1 The the DT cord-005646-xhx9pzhj 970 2 elevated elevated JJ cord-005646-xhx9pzhj 970 3 count count NN cord-005646-xhx9pzhj 970 4 of of IN cord-005646-xhx9pzhj 970 5 white white JJ cord-005646-xhx9pzhj 970 6 cells cell NNS cord-005646-xhx9pzhj 970 7 and and CC cord-005646-xhx9pzhj 970 8 PMNs pmn NNS cord-005646-xhx9pzhj 970 9 , , , cord-005646-xhx9pzhj 970 10 either either CC cord-005646-xhx9pzhj 970 11 alone alone RB cord-005646-xhx9pzhj 970 12 or or CC cord-005646-xhx9pzhj 970 13 associated associate VBN cord-005646-xhx9pzhj 970 14 to to IN cord-005646-xhx9pzhj 970 15 one one CD cord-005646-xhx9pzhj 970 16 rapid rapid JJ cord-005646-xhx9pzhj 970 17 regeneration regeneration NN cord-005646-xhx9pzhj 970 18 of of IN cord-005646-xhx9pzhj 970 19 platelets platelet NNS cord-005646-xhx9pzhj 970 20 , , , cord-005646-xhx9pzhj 970 21 seems seem VBZ cord-005646-xhx9pzhj 970 22 enabled enable VBN cord-005646-xhx9pzhj 970 23 to to TO cord-005646-xhx9pzhj 970 24 predict predict VB cord-005646-xhx9pzhj 970 25 an an DT cord-005646-xhx9pzhj 970 26 unfavorable unfavorable JJ cord-005646-xhx9pzhj 970 27 evolution evolution NN cord-005646-xhx9pzhj 970 28 of of IN cord-005646-xhx9pzhj 970 29 the the DT cord-005646-xhx9pzhj 970 30 HUS HUS NNP cord-005646-xhx9pzhj 970 31 in in IN cord-005646-xhx9pzhj 970 32 children child NNS cord-005646-xhx9pzhj 970 33 . . . cord-005646-xhx9pzhj 971 1 MSUD MSUD NNP cord-005646-xhx9pzhj 971 2 results result VBZ cord-005646-xhx9pzhj 971 3 from from IN cord-005646-xhx9pzhj 971 4 an an DT cord-005646-xhx9pzhj 971 5 inherited inherit VBN cord-005646-xhx9pzhj 971 6 impairement impairement NN cord-005646-xhx9pzhj 971 7 of of IN cord-005646-xhx9pzhj 971 8 catabolic catabolic JJ cord-005646-xhx9pzhj 971 9 pathway pathway NN cord-005646-xhx9pzhj 971 10 of of IN cord-005646-xhx9pzhj 971 11 branch branch NN cord-005646-xhx9pzhj 971 12 chain chain NN cord-005646-xhx9pzhj 971 13 amino amino NNS cord-005646-xhx9pzhj 971 14 - - HYPH cord-005646-xhx9pzhj 971 15 acids acid NNS cord-005646-xhx9pzhj 971 16 . . . cord-005646-xhx9pzhj 972 1 High high JJ cord-005646-xhx9pzhj 972 2 leucine leucine NN cord-005646-xhx9pzhj 972 3 blood blood NN cord-005646-xhx9pzhj 972 4 levels level NNS cord-005646-xhx9pzhj 972 5 may may MD cord-005646-xhx9pzhj 972 6 induce induce VB cord-005646-xhx9pzhj 972 7 acute acute JJ cord-005646-xhx9pzhj 972 8 brain brain NN cord-005646-xhx9pzhj 972 9 dysfunction dysfunction NN cord-005646-xhx9pzhj 972 10 . . . cord-005646-xhx9pzhj 973 1 This this DT cord-005646-xhx9pzhj 973 2 dramatic dramatic JJ cord-005646-xhx9pzhj 973 3 complication complication NN cord-005646-xhx9pzhj 973 4 led lead VBD cord-005646-xhx9pzhj 973 5 us -PRON- PRP cord-005646-xhx9pzhj 973 6 to to TO cord-005646-xhx9pzhj 973 7 propose propose VB cord-005646-xhx9pzhj 973 8 leucine leucine NN cord-005646-xhx9pzhj 973 9 removal removal NN cord-005646-xhx9pzhj 973 10 procedures procedure NNS cord-005646-xhx9pzhj 973 11 as as IN cord-005646-xhx9pzhj 973 12 continuous continuous JJ cord-005646-xhx9pzhj 973 13 hemofiltration hemofiltration NN cord-005646-xhx9pzhj 973 14 . . . cord-005646-xhx9pzhj 974 1 Patients patient NNS cord-005646-xhx9pzhj 974 2 and and CC cord-005646-xhx9pzhj 974 3 methods method NNS cord-005646-xhx9pzhj 974 4 Three three CD cord-005646-xhx9pzhj 974 5 newborns newborn NNS cord-005646-xhx9pzhj 974 6 in in IN cord-005646-xhx9pzhj 974 7 acute acute JJ cord-005646-xhx9pzhj 974 8 MSUD MSUD NNP cord-005646-xhx9pzhj 974 9 onset onset NN cord-005646-xhx9pzhj 974 10 were be VBD cord-005646-xhx9pzhj 974 11 treated treat VBN cord-005646-xhx9pzhj 974 12 by by IN cord-005646-xhx9pzhj 974 13 HF HF NNP cord-005646-xhx9pzhj 974 14 , , , cord-005646-xhx9pzhj 974 15 HDF HDF NNP cord-005646-xhx9pzhj 974 16 and and CC cord-005646-xhx9pzhj 974 17 HD hd NN cord-005646-xhx9pzhj 974 18 . . . cord-005646-xhx9pzhj 975 1 Extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 975 2 circulation circulation NN cord-005646-xhx9pzhj 975 3 was be VBD cord-005646-xhx9pzhj 975 4 performed perform VBN cord-005646-xhx9pzhj 975 5 through through IN cord-005646-xhx9pzhj 975 6 a a DT cord-005646-xhx9pzhj 975 7 6.5 6.5 CD cord-005646-xhx9pzhj 975 8 Fr Fr NNP cord-005646-xhx9pzhj 975 9 catheter catheter NN cord-005646-xhx9pzhj 975 10 , , , cord-005646-xhx9pzhj 975 11 a a DT cord-005646-xhx9pzhj 975 12 circuit circuit NN cord-005646-xhx9pzhj 975 13 with with IN cord-005646-xhx9pzhj 975 14 a a DT cord-005646-xhx9pzhj 975 15 blood blood NN cord-005646-xhx9pzhj 975 16 pump pump NN cord-005646-xhx9pzhj 975 17 ( ( -LRB- cord-005646-xhx9pzhj 975 18 priming prime VBG cord-005646-xhx9pzhj 975 19 volume volume NN cord-005646-xhx9pzhj 975 20 = = SYM cord-005646-xhx9pzhj 975 21 40 40 CD cord-005646-xhx9pzhj 975 22 ml ml NN cord-005646-xhx9pzhj 975 23 ) ) -RRB- cord-005646-xhx9pzhj 975 24 . . . cord-005646-xhx9pzhj 976 1 Patients patient NNS cord-005646-xhx9pzhj 976 2 and and CC cord-005646-xhx9pzhj 976 3 procedures procedure NNS cord-005646-xhx9pzhj 976 4 characteristics characteristic NNS cord-005646-xhx9pzhj 976 5 are be VBP cord-005646-xhx9pzhj 976 6 summarized summarize VBN cord-005646-xhx9pzhj 976 7 below below IN cord-005646-xhx9pzhj 976 8 in in IN cord-005646-xhx9pzhj 976 9 the the DT cord-005646-xhx9pzhj 976 10 Sucralfate sucralfate NN cord-005646-xhx9pzhj 976 11 ( ( -LRB- cord-005646-xhx9pzhj 976 12 an an DT cord-005646-xhx9pzhj 976 13 aluminium aluminium NN cord-005646-xhx9pzhj 976 14 salt salt NN cord-005646-xhx9pzhj 976 15 of of IN cord-005646-xhx9pzhj 976 16 sucrose sucrose JJ cord-005646-xhx9pzhj 976 17 octa octa NNP cord-005646-xhx9pzhj 976 18 sulfate sulfate NNP cord-005646-xhx9pzhj 976 19 ) ) -RRB- cord-005646-xhx9pzhj 976 20 is be VBZ cord-005646-xhx9pzhj 976 21 used use VBN cord-005646-xhx9pzhj 976 22 to to TO cord-005646-xhx9pzhj 976 23 prevent prevent VB cord-005646-xhx9pzhj 976 24 and and CC cord-005646-xhx9pzhj 976 25 treat treat VB cord-005646-xhx9pzhj 976 26 upper upper JJ cord-005646-xhx9pzhj 976 27 gastrointestinal gastrointestinal JJ cord-005646-xhx9pzhj 976 28 bleeding bleeding NN cord-005646-xhx9pzhj 976 29 in in IN cord-005646-xhx9pzhj 976 30 critically critically RB cord-005646-xhx9pzhj 976 31 ill ill JJ cord-005646-xhx9pzhj 976 32 patients patient NNS cord-005646-xhx9pzhj 976 33 . . . cord-005646-xhx9pzhj 977 1 With with IN cord-005646-xhx9pzhj 977 2 minimal minimal JJ cord-005646-xhx9pzhj 977 3 absorption absorption NN cord-005646-xhx9pzhj 977 4 , , , cord-005646-xhx9pzhj 977 5 the the DT cord-005646-xhx9pzhj 977 6 potential potential NN cord-005646-xhx9pzhj 977 7 for for IN cord-005646-xhx9pzhj 977 8 side side JJ cord-005646-xhx9pzhj 977 9 effects effect NNS cord-005646-xhx9pzhj 977 10 is be VBZ cord-005646-xhx9pzhj 977 11 thought think VBN cord-005646-xhx9pzhj 977 12 to to TO cord-005646-xhx9pzhj 977 13 be be VB cord-005646-xhx9pzhj 977 14 limited limit VBN cord-005646-xhx9pzhj 977 15 , , , cord-005646-xhx9pzhj 977 16 though though IN cord-005646-xhx9pzhj 977 17 aluminium aluminium NN cord-005646-xhx9pzhj 977 18 toxicity toxicity NN cord-005646-xhx9pzhj 977 19 has have VBZ cord-005646-xhx9pzhj 977 20 been be VBN cord-005646-xhx9pzhj 977 21 reported report VBN cord-005646-xhx9pzhj 977 22 in in IN cord-005646-xhx9pzhj 977 23 patients patient NNS cord-005646-xhx9pzhj 977 24 with with IN cord-005646-xhx9pzhj 977 25 chronic chronic JJ cord-005646-xhx9pzhj 977 26 renal renal JJ cord-005646-xhx9pzhj 977 27 failure failure NN cord-005646-xhx9pzhj 977 28 . . . cord-005646-xhx9pzhj 978 1 These these DT cord-005646-xhx9pzhj 978 2 patients patient NNS cord-005646-xhx9pzhj 978 3 may may MD cord-005646-xhx9pzhj 978 4 already already RB cord-005646-xhx9pzhj 978 5 have have VB cord-005646-xhx9pzhj 978 6 had have VBN cord-005646-xhx9pzhj 978 7 high high JJ cord-005646-xhx9pzhj 978 8 body body NN cord-005646-xhx9pzhj 978 9 stores store NNS cord-005646-xhx9pzhj 978 10 of of IN cord-005646-xhx9pzhj 978 11 aluminium aluminium NN cord-005646-xhx9pzhj 978 12 . . . cord-005646-xhx9pzhj 979 1 We -PRON- PRP cord-005646-xhx9pzhj 979 2 report report VBP cord-005646-xhx9pzhj 979 3 5 5 CD cord-005646-xhx9pzhj 979 4 critically critically RB cord-005646-xhx9pzhj 979 5 ill ill JJ cord-005646-xhx9pzhj 979 6 children child NNS cord-005646-xhx9pzhj 979 7 with with IN cord-005646-xhx9pzhj 979 8 high high JJ cord-005646-xhx9pzhj 979 9 serum serum NN cord-005646-xhx9pzhj 979 10 concentrations concentration NNS cord-005646-xhx9pzhj 979 11 of of IN cord-005646-xhx9pzhj 979 12 aluminium aluminium NN cord-005646-xhx9pzhj 979 13 following follow VBG cord-005646-xhx9pzhj 979 14 sucralfate sucralfate JJ cord-005646-xhx9pzhj 979 15 therapy therapy NN cord-005646-xhx9pzhj 979 16 . . . cord-005646-xhx9pzhj 980 1 All all DT cord-005646-xhx9pzhj 980 2 5 5 CD cord-005646-xhx9pzhj 980 3 had have VBD cord-005646-xhx9pzhj 980 4 renal renal JJ cord-005646-xhx9pzhj 980 5 impairment impairment NN cord-005646-xhx9pzhj 980 6 . . . cord-005646-xhx9pzhj 981 1 The the DT cord-005646-xhx9pzhj 981 2 normal normal JJ cord-005646-xhx9pzhj 981 3 aluminium aluminium NN cord-005646-xhx9pzhj 981 4 level level NN cord-005646-xhx9pzhj 981 5 is be VBZ cord-005646-xhx9pzhj 981 6 < < XX cord-005646-xhx9pzhj 981 7 0.4 0.4 CD cord-005646-xhx9pzhj 981 8 gmol gmol NNP cord-005646-xhx9pzhj 981 9 / / SYM cord-005646-xhx9pzhj 981 10 L L NNP cord-005646-xhx9pzhj 981 11 and and CC cord-005646-xhx9pzhj 981 12 in in IN cord-005646-xhx9pzhj 981 13 patients patient NNS cord-005646-xhx9pzhj 981 14 with with IN cord-005646-xhx9pzhj 981 15 chronic chronic JJ cord-005646-xhx9pzhj 981 16 renal renal JJ cord-005646-xhx9pzhj 981 17 failure failure NN cord-005646-xhx9pzhj 982 1 < < XX cord-005646-xhx9pzhj 982 2 2.2 2.2 CD cord-005646-xhx9pzhj 982 3 ] ] -RRB- cord-005646-xhx9pzhj 983 1 .tmol/ .tmol/ NFP cord-005646-xhx9pzhj 984 1 L. L. NNP cord-005646-xhx9pzhj 984 2 None none NN cord-005646-xhx9pzhj 984 3 of of IN cord-005646-xhx9pzhj 984 4 these these DT cord-005646-xhx9pzhj 984 5 patients patient NNS cord-005646-xhx9pzhj 984 6 had have VBD cord-005646-xhx9pzhj 984 7 known know VBN cord-005646-xhx9pzhj 984 8 preexisting preexisting JJ cord-005646-xhx9pzhj 984 9 chronic chronic JJ cord-005646-xhx9pzhj 984 10 renal renal JJ cord-005646-xhx9pzhj 984 11 disease disease NN cord-005646-xhx9pzhj 984 12 . . . cord-005646-xhx9pzhj 985 1 CPB CPB NNP cord-005646-xhx9pzhj 985 2 was be VBD cord-005646-xhx9pzhj 985 3 conducted conduct VBN cord-005646-xhx9pzhj 985 4 under under IN cord-005646-xhx9pzhj 985 5 deep deep JJ cord-005646-xhx9pzhj 985 6 hypothermia hypothermia NN cord-005646-xhx9pzhj 985 7 ( ( -LRB- cord-005646-xhx9pzhj 985 8 T, T, NNP cord-005646-xhx9pzhj 985 9 ° ° NNP cord-005646-xhx9pzhj 985 10 16 16 CD cord-005646-xhx9pzhj 985 11 ° ° NN cord-005646-xhx9pzhj 985 12 C C NNP cord-005646-xhx9pzhj 985 13 ) ) -RRB- cord-005646-xhx9pzhj 985 14 and and CC cord-005646-xhx9pzhj 985 15 cardiocirculatory cardiocirculatory NN cord-005646-xhx9pzhj 985 16 arrest arrest NN cord-005646-xhx9pzhj 985 17 ( ( -LRB- cord-005646-xhx9pzhj 985 18 CCA CCA NNP cord-005646-xhx9pzhj 985 19 ) ) -RRB- cord-005646-xhx9pzhj 985 20 or or CC cord-005646-xhx9pzhj 985 21 under under IN cord-005646-xhx9pzhj 985 22 hypothermia hypothermia NN cord-005646-xhx9pzhj 985 23 ( ( -LRB- cord-005646-xhx9pzhj 985 24 T, T, NNP cord-005646-xhx9pzhj 985 25 ° ° JJ cord-005646-xhx9pzhj 985 26 24 24 CD cord-005646-xhx9pzhj 985 27 ° ° NN cord-005646-xhx9pzhj 985 28 C c NN cord-005646-xhx9pzhj 985 29 ) ) -RRB- cord-005646-xhx9pzhj 985 30 and and CC cord-005646-xhx9pzhj 985 31 low low JJ cord-005646-xhx9pzhj 985 32 - - HYPH cord-005646-xhx9pzhj 985 33 flow flow NN cord-005646-xhx9pzhj 985 34 perfusion perfusion NN cord-005646-xhx9pzhj 985 35 . . . cord-005646-xhx9pzhj 986 1 Continuous Continuous NNP cord-005646-xhx9pzhj 986 2 Holter Holter NNP cord-005646-xhx9pzhj 986 3 - - HYPH cord-005646-xhx9pzhj 986 4 electrocardiograms electrocardiogram NNS cord-005646-xhx9pzhj 986 5 ( ( -LRB- cord-005646-xhx9pzhj 986 6 H H NNP cord-005646-xhx9pzhj 986 7 - - HYPH cord-005646-xhx9pzhj 986 8 ECG ECG NNP cord-005646-xhx9pzhj 986 9 ) ) -RRB- cord-005646-xhx9pzhj 986 10 were be VBD cord-005646-xhx9pzhj 986 11 recorded record VBN cord-005646-xhx9pzhj 986 12 from from IN cord-005646-xhx9pzhj 986 13 the the DT cord-005646-xhx9pzhj 986 14 ilranediate ilranediate JJ cord-005646-xhx9pzhj 986 15 postoperative postoperative NN cord-005646-xhx9pzhj 986 16 ( ( -LRB- cord-005646-xhx9pzhj 986 17 PO po NN cord-005646-xhx9pzhj 986 18 ) ) -RRB- cord-005646-xhx9pzhj 986 19 period period NN cord-005646-xhx9pzhj 986 20 on on IN cord-005646-xhx9pzhj 986 21 for for IN cord-005646-xhx9pzhj 986 22 72 72 CD cord-005646-xhx9pzhj 986 23 hours hour NNS cord-005646-xhx9pzhj 986 24 . . . cord-005646-xhx9pzhj 987 1 H H NNP cord-005646-xhx9pzhj 987 2 - - HYPH cord-005646-xhx9pzhj 987 3 ECG ECG NNP cord-005646-xhx9pzhj 987 4 were be VBD cord-005646-xhx9pzhj 987 5 also also RB cord-005646-xhx9pzhj 987 6 recorded record VBN cord-005646-xhx9pzhj 987 7 prior prior RB cord-005646-xhx9pzhj 987 8 to to IN cord-005646-xhx9pzhj 987 9 the the DT cord-005646-xhx9pzhj 987 10 operation operation NN cord-005646-xhx9pzhj 987 11 and and CC cord-005646-xhx9pzhj 987 12 before before IN cord-005646-xhx9pzhj 987 13 discharge discharge NN cord-005646-xhx9pzhj 987 14 . . . cord-005646-xhx9pzhj 988 1 Following follow VBG cord-005646-xhx9pzhj 988 2 DR DR NNP cord-005646-xhx9pzhj 988 3 were be VBD cord-005646-xhx9pzhj 988 4 observed observe VBN cord-005646-xhx9pzhj 988 5 : : : cord-005646-xhx9pzhj 988 6 snpraventricutar snpraventricutar NNP cord-005646-xhx9pzhj 988 7 ( ( -LRB- cord-005646-xhx9pzhj 988 8 SV SV NNP cord-005646-xhx9pzhj 988 9 ) ) -RRB- cord-005646-xhx9pzhj 988 10 and and CC cord-005646-xhx9pzhj 988 11 ventricular ventricular JJ cord-005646-xhx9pzhj 988 12 ( ( -LRB- cord-005646-xhx9pzhj 988 13 V v NN cord-005646-xhx9pzhj 988 14 ) ) -RRB- cord-005646-xhx9pzhj 988 15 extrasystoles extrasystole NNS cord-005646-xhx9pzhj 988 16 ( ( -LRB- cord-005646-xhx9pzhj 988 17 ES ES NNP cord-005646-xhx9pzhj 988 18 ) ) -RRB- cord-005646-xhx9pzhj 988 19 ( ( -LRB- cord-005646-xhx9pzhj 988 20 > > XX cord-005646-xhx9pzhj 988 21 50/24h 50/24h CD cord-005646-xhx9pzhj 988 22 ) ) -RRB- cord-005646-xhx9pzhj 988 23 , , , cord-005646-xhx9pzhj 988 24 SV SV NNP cord-005646-xhx9pzhj 988 25 and and CC cord-005646-xhx9pzhj 988 26 V v NN cord-005646-xhx9pzhj 988 27 tachycardia tachycardia NN cord-005646-xhx9pzhj 988 28 ( ( -LRB- cord-005646-xhx9pzhj 988 29 SVT SVT NNP cord-005646-xhx9pzhj 988 30 and and CC cord-005646-xhx9pzhj 988 31 VT VT NNP cord-005646-xhx9pzhj 988 32 ) ) -RRB- cord-005646-xhx9pzhj 988 33 , , , cord-005646-xhx9pzhj 988 34 accelerated accelerate VBD cord-005646-xhx9pzhj 988 35 junctional junctional JJ cord-005646-xhx9pzhj 988 36 rhythm rhythm NN cord-005646-xhx9pzhj 988 37 ( ( -LRB- cord-005646-xhx9pzhj 988 38 AJR AJR NNP cord-005646-xhx9pzhj 988 39 ) ) -RRB- cord-005646-xhx9pzhj 988 40 and and CC cord-005646-xhx9pzhj 988 41 junctional junctional JJ cord-005646-xhx9pzhj 988 42 ectopic ectopic JJ cord-005646-xhx9pzhj 988 43 tachycardja tachycardja NN cord-005646-xhx9pzhj 988 44 ( ( -LRB- cord-005646-xhx9pzhj 988 45 JET jet NN cord-005646-xhx9pzhj 988 46 ) ) -RRB- cord-005646-xhx9pzhj 988 47 , , , cord-005646-xhx9pzhj 988 48 and and CC cord-005646-xhx9pzhj 988 49 2nd 2nd JJ cord-005646-xhx9pzhj 988 50 and and CC cord-005646-xhx9pzhj 988 51 3rd 3rd JJ cord-005646-xhx9pzhj 988 52 degree degree NN cord-005646-xhx9pzhj 988 53 atrioventricular atrioventricular JJ cord-005646-xhx9pzhj 988 54 block block NN cord-005646-xhx9pzhj 988 55 ( ( -LRB- cord-005646-xhx9pzhj 988 56 AVB2 AVB2 NNP cord-005646-xhx9pzhj 988 57 and and CC cord-005646-xhx9pzhj 988 58 AVB3 AVB3 NNP cord-005646-xhx9pzhj 988 59 ) ) -RRB- cord-005646-xhx9pzhj 988 60 . . . cord-005646-xhx9pzhj 989 1 The the DT cord-005646-xhx9pzhj 989 2 incidence incidence NN cord-005646-xhx9pzhj 989 3 of of IN cord-005646-xhx9pzhj 989 4 PO PO NNP cord-005646-xhx9pzhj 989 5 DR DR NNP cord-005646-xhx9pzhj 989 6 was be VBD cord-005646-xhx9pzhj 989 7 20 20 CD cord-005646-xhx9pzhj 989 8 % % NN cord-005646-xhx9pzhj 989 9 in in IN cord-005646-xhx9pzhj 989 10 the the DT cord-005646-xhx9pzhj 989 11 pre pre JJ cord-005646-xhx9pzhj 989 12 - - JJ cord-005646-xhx9pzhj 989 13 op op JJ cord-005646-xhx9pzhj 989 14 H H NNP cord-005646-xhx9pzhj 989 15 - - HYPH cord-005646-xhx9pzhj 989 16 ECG ECG NNP cord-005646-xhx9pzhj 989 17 , , , cord-005646-xhx9pzhj 989 18 74 74 CD cord-005646-xhx9pzhj 989 19 % % NN cord-005646-xhx9pzhj 989 20 on on IN cord-005646-xhx9pzhj 989 21 the the DT cord-005646-xhx9pzhj 989 22 1st 1st NN cord-005646-xhx9pzhj 989 23 , , , cord-005646-xhx9pzhj 989 24 33 33 CD cord-005646-xhx9pzhj 989 25 % % NN cord-005646-xhx9pzhj 989 26 on on IN cord-005646-xhx9pzhj 989 27 the the DT cord-005646-xhx9pzhj 989 28 2rid 2rid CD cord-005646-xhx9pzhj 989 29 , , , cord-005646-xhx9pzhj 989 30 34 34 CD cord-005646-xhx9pzhj 989 31 % % NN cord-005646-xhx9pzhj 989 32 on on IN cord-005646-xhx9pzhj 989 33 the the DT cord-005646-xhx9pzhj 989 34 3rd 3rd JJ cord-005646-xhx9pzhj 989 35 PO PO NNP cord-005646-xhx9pzhj 989 36 day day NN cord-005646-xhx9pzhj 989 37 and and CC cord-005646-xhx9pzhj 989 38 21 21 CD cord-005646-xhx9pzhj 989 39 % % NN cord-005646-xhx9pzhj 989 40 befbre befbre NN cord-005646-xhx9pzhj 989 41 discharge discharge NN cord-005646-xhx9pzhj 989 42 . . . cord-005646-xhx9pzhj 990 1 Compared compare VBN cord-005646-xhx9pzhj 990 2 to to IN cord-005646-xhx9pzhj 990 3 the the DT cord-005646-xhx9pzhj 990 4 pre pre JJ cord-005646-xhx9pzhj 990 5 - - JJ cord-005646-xhx9pzhj 990 6 op op JJ cord-005646-xhx9pzhj 990 7 findings finding NNS cord-005646-xhx9pzhj 990 8 , , , cord-005646-xhx9pzhj 990 9 an an DT cord-005646-xhx9pzhj 990 10 increased increase VBN cord-005646-xhx9pzhj 990 11 incidence incidence NN cord-005646-xhx9pzhj 990 12 of of IN cord-005646-xhx9pzhj 990 13 SVES SVES NNP cord-005646-xhx9pzhj 990 14 , , , cord-005646-xhx9pzhj 990 15 VES VES NNP cord-005646-xhx9pzhj 990 16 , , , cord-005646-xhx9pzhj 990 17 SVT SVT NNP cord-005646-xhx9pzhj 990 18 and and CC cord-005646-xhx9pzhj 990 19 AVB3 AVB3 NNPS cord-005646-xhx9pzhj 990 20 on on IN cord-005646-xhx9pzhj 990 21 the the DT cord-005646-xhx9pzhj 990 22 1st 1st JJ cord-005646-xhx9pzhj 990 23 PO PO NNP cord-005646-xhx9pzhj 990 24 day day NN cord-005646-xhx9pzhj 990 25 was be VBD cord-005646-xhx9pzhj 990 26 observed observe VBN cord-005646-xhx9pzhj 990 27 , , , cord-005646-xhx9pzhj 990 28 whereas whereas IN cord-005646-xhx9pzhj 990 29 VT VT NNP cord-005646-xhx9pzhj 990 30 and and CC cord-005646-xhx9pzhj 990 31 A a DT cord-005646-xhx9pzhj 990 32 JR JR NNP cord-005646-xhx9pzhj 990 33 or or CC cord-005646-xhx9pzhj 990 34 JET JET NNP cord-005646-xhx9pzhj 990 35 were be VBD cord-005646-xhx9pzhj 990 36 exclusively exclusively RB cord-005646-xhx9pzhj 990 37 observed observe VBN cord-005646-xhx9pzhj 990 38 PO po NN cord-005646-xhx9pzhj 990 39 . . . cord-005646-xhx9pzhj 991 1 All all DT cord-005646-xhx9pzhj 991 2 types type NNS cord-005646-xhx9pzhj 991 3 of of IN cord-005646-xhx9pzhj 991 4 DR DR NNP cord-005646-xhx9pzhj 991 5 were be VBD cord-005646-xhx9pzhj 991 6 observed observe VBN cord-005646-xhx9pzhj 991 7 up up RP cord-005646-xhx9pzhj 991 8 to to IN cord-005646-xhx9pzhj 991 9 the the DT cord-005646-xhx9pzhj 991 10 3rd 3rd JJ cord-005646-xhx9pzhj 991 11 PO PO NNP cord-005646-xhx9pzhj 991 12 day day NN cord-005646-xhx9pzhj 991 13 . . . cord-005646-xhx9pzhj 992 1 Ty23e ty23e NN cord-005646-xhx9pzhj 992 2 of of IN cord-005646-xhx9pzhj 992 3 DR DR NNP cord-005646-xhx9pzhj 992 4 before before IN cord-005646-xhx9pzhj 992 5 discharge discharge NN cord-005646-xhx9pzhj 992 6 was be VBD cord-005646-xhx9pzhj 992 7 similar similar JJ cord-005646-xhx9pzhj 992 8 to to TO cord-005646-xhx9pzhj 992 9 pre pre VB cord-005646-xhx9pzhj 992 10 - - JJ cord-005646-xhx9pzhj 992 11 op op JJ cord-005646-xhx9pzhj 992 12 findings finding NNS cord-005646-xhx9pzhj 992 13 and and CC cord-005646-xhx9pzhj 992 14 there there EX cord-005646-xhx9pzhj 992 15 was be VBD cord-005646-xhx9pzhj 992 16 no no DT cord-005646-xhx9pzhj 992 17 definitive definitive JJ cord-005646-xhx9pzhj 992 18 AVB3 AVB3 NNPS cord-005646-xhx9pzhj 992 19 . . . cord-005646-xhx9pzhj 993 1 Considering consider VBG cord-005646-xhx9pzhj 993 2 patient patient JJ cord-005646-xhx9pzhj 993 3 groups group NNS cord-005646-xhx9pzhj 993 4 according accord VBG cord-005646-xhx9pzhj 993 5 to to IN cord-005646-xhx9pzhj 993 6 the the DT cord-005646-xhx9pzhj 993 7 most most RBS cord-005646-xhx9pzhj 993 8 frequent frequent JJ cord-005646-xhx9pzhj 993 9 isolated isolate VBN cord-005646-xhx9pzhj 993 10 op op NN cord-005646-xhx9pzhj 993 11 - - HYPH cord-005646-xhx9pzhj 993 12 procedure procedure NN cord-005646-xhx9pzhj 993 13 , , , cord-005646-xhx9pzhj 993 14 the the DT cord-005646-xhx9pzhj 993 15 incidence incidence NN cord-005646-xhx9pzhj 993 16 of of IN cord-005646-xhx9pzhj 993 17 DR DR NNP cord-005646-xhx9pzhj 993 18 on on IN cord-005646-xhx9pzhj 993 19 the the DT cord-005646-xhx9pzhj 993 20 first first JJ cord-005646-xhx9pzhj 993 21 PO PO NNP cord-005646-xhx9pzhj 993 22 day day NN cord-005646-xhx9pzhj 993 23 was be VBD cord-005646-xhx9pzhj 994 1 56 56 CD cord-005646-xhx9pzhj 994 2 % % NN cord-005646-xhx9pzhj 994 3 after after IN cord-005646-xhx9pzhj 994 4 ASD ASD NNP cord-005646-xhx9pzhj 994 5 II II NNP cord-005646-xhx9pzhj 994 6 - - HYPH cord-005646-xhx9pzhj 994 7 closure closure NN cord-005646-xhx9pzhj 994 8 ( ( -LRB- cord-005646-xhx9pzhj 994 9 n=23 n=23 NNP cord-005646-xhx9pzhj 994 10 ) ) -RRB- cord-005646-xhx9pzhj 994 11 , , , cord-005646-xhx9pzhj 994 12 74 74 CD cord-005646-xhx9pzhj 994 13 % % NN cord-005646-xhx9pzhj 994 14 after after IN cord-005646-xhx9pzhj 994 15 stthaortal stthaortal NNP cord-005646-xhx9pzhj 994 16 VSD VSD NNP cord-005646-xhx9pzhj 994 17 - - HYPH cord-005646-xhx9pzhj 994 18 closure closure NN cord-005646-xhx9pzhj 994 19 ( ( -LRB- cord-005646-xhx9pzhj 994 20 n n NN cord-005646-xhx9pzhj 994 21 = = SYM cord-005646-xhx9pzhj 994 22 lg lg NNP cord-005646-xhx9pzhj 994 23 ) ) -RRB- cord-005646-xhx9pzhj 994 24 , , , cord-005646-xhx9pzhj 994 25 75 75 CD cord-005646-xhx9pzhj 994 26 % % NN cord-005646-xhx9pzhj 994 27 after after IN cord-005646-xhx9pzhj 994 28 correction correction NN cord-005646-xhx9pzhj 994 29 of of IN cord-005646-xhx9pzhj 994 30 a a DT cord-005646-xhx9pzhj 994 31 complete complete JJ cord-005646-xhx9pzhj 994 32 AVSD AVSD NNP cord-005646-xhx9pzhj 994 33 ( ( -LRB- cord-005646-xhx9pzhj 994 34 n=8 n=8 NNP cord-005646-xhx9pzhj 994 35 ) ) -RRB- cord-005646-xhx9pzhj 994 36 , , , cord-005646-xhx9pzhj 994 37 80 80 CD cord-005646-xhx9pzhj 994 38 % % NN cord-005646-xhx9pzhj 994 39 after after IN cord-005646-xhx9pzhj 994 40 correction correction NN cord-005646-xhx9pzhj 994 41 of of IN cord-005646-xhx9pzhj 994 42 a a DT cord-005646-xhx9pzhj 994 43 tetralogy tetralogy NN cord-005646-xhx9pzhj 994 44 of of IN cord-005646-xhx9pzhj 994 45 Fallot Fallot NNP cord-005646-xhx9pzhj 994 46 ( ( -LRB- cord-005646-xhx9pzhj 994 47 n=20 n=20 NNP cord-005646-xhx9pzhj 994 48 ) ) -RRB- cord-005646-xhx9pzhj 994 49 and and CC cord-005646-xhx9pzhj 994 50 100 100 CD cord-005646-xhx9pzhj 994 51 % % NN cord-005646-xhx9pzhj 994 52 after after IN cord-005646-xhx9pzhj 994 53 Fontan Fontan NNP cord-005646-xhx9pzhj 994 54 - - HYPH cord-005646-xhx9pzhj 994 55 operation operation NN cord-005646-xhx9pzhj 994 56 ( ( -LRB- cord-005646-xhx9pzhj 994 57 n=10 n=10 NNP cord-005646-xhx9pzhj 994 58 ) ) -RRB- cord-005646-xhx9pzhj 994 59 . . . cord-005646-xhx9pzhj 995 1 Incidence incidence NN cord-005646-xhx9pzhj 995 2 and and CC cord-005646-xhx9pzhj 995 3 type type NN cord-005646-xhx9pzhj 995 4 of of IN cord-005646-xhx9pzhj 995 5 DR DR NNP cord-005646-xhx9pzhj 995 6 were be VBD cord-005646-xhx9pzhj 995 7 not not RB cord-005646-xhx9pzhj 995 8 significantly significantly RB cord-005646-xhx9pzhj 995 9 different different JJ cord-005646-xhx9pzhj 995 10 between between IN cord-005646-xhx9pzhj 995 11 groups group NNS cord-005646-xhx9pzhj 995 12 . . . cord-005646-xhx9pzhj 996 1 Longer long JJR cord-005646-xhx9pzhj 996 2 CPB CPB NNP cord-005646-xhx9pzhj 996 3 - - HYPH cord-005646-xhx9pzhj 996 4 dttration dttration NN cord-005646-xhx9pzhj 996 5 and and CC cord-005646-xhx9pzhj 996 6 use use NN cord-005646-xhx9pzhj 996 7 of of IN cord-005646-xhx9pzhj 996 8 CCA CCA NNP cord-005646-xhx9pzhj 996 9 were be VBD cord-005646-xhx9pzhj 996 10 risk risk NN cord-005646-xhx9pzhj 996 11 factors factor NNS cord-005646-xhx9pzhj 996 12 for for IN cord-005646-xhx9pzhj 996 13 PO PO NNP cord-005646-xhx9pzhj 996 14 VES VES NNP cord-005646-xhx9pzhj 996 15 and and CC cord-005646-xhx9pzhj 996 16 VT VT NNP cord-005646-xhx9pzhj 996 17 ( ( -LRB- cord-005646-xhx9pzhj 996 18 p<0,005 p<0,005 NNP cord-005646-xhx9pzhj 996 19 and and CC cord-005646-xhx9pzhj 996 20 p<0,05 p<0,05 NNP cord-005646-xhx9pzhj 996 21 , , , cord-005646-xhx9pzhj 996 22 respectively respectively RB cord-005646-xhx9pzhj 996 23 ) ) -RRB- cord-005646-xhx9pzhj 996 24 whereas whereas IN cord-005646-xhx9pzhj 996 25 use use NN cord-005646-xhx9pzhj 996 26 of of IN cord-005646-xhx9pzhj 996 27 CCA CCA NNP cord-005646-xhx9pzhj 996 28 and and CC cord-005646-xhx9pzhj 996 29 degree degree NN cord-005646-xhx9pzhj 996 30 of of IN cord-005646-xhx9pzhj 996 31 hypothermia hypothermia NN cord-005646-xhx9pzhj 996 32 were be VBD cord-005646-xhx9pzhj 996 33 risk risk NN cord-005646-xhx9pzhj 996 34 factors factor NNS cord-005646-xhx9pzhj 996 35 for for IN cord-005646-xhx9pzhj 996 36 the the DT cord-005646-xhx9pzhj 996 37 development development NN cord-005646-xhx9pzhj 996 38 of of IN cord-005646-xhx9pzhj 996 39 A a DT cord-005646-xhx9pzhj 996 40 JR JR NNP cord-005646-xhx9pzhj 996 41 and and CC cord-005646-xhx9pzhj 996 42 JET JET NNP cord-005646-xhx9pzhj 996 43 ( ( -LRB- cord-005646-xhx9pzhj 996 44 p<0,02 p<0,02 NNP cord-005646-xhx9pzhj 996 45 and and CC cord-005646-xhx9pzhj 996 46 p<0,0001 p<0,0001 VBD cord-005646-xhx9pzhj 996 47 , , , cord-005646-xhx9pzhj 996 48 respectively respectively RB cord-005646-xhx9pzhj 996 49 ) ) -RRB- cord-005646-xhx9pzhj 996 50 . . . cord-005646-xhx9pzhj 997 1 -Our -Our NNP cord-005646-xhx9pzhj 998 1 results result NNS cord-005646-xhx9pzhj 998 2 indicate indicate VBP cord-005646-xhx9pzhj 998 3 that that IN cord-005646-xhx9pzhj 998 4 PO PO NNP cord-005646-xhx9pzhj 998 5 DR DR NNP cord-005646-xhx9pzhj 998 6 after after IN cord-005646-xhx9pzhj 998 7 CPB CPB NNP cord-005646-xhx9pzhj 998 8 in in IN cord-005646-xhx9pzhj 998 9 children child NNS cord-005646-xhx9pzhj 998 10 m'e m'e VBP cord-005646-xhx9pzhj 998 11 frequent frequent JJ cord-005646-xhx9pzhj 998 12 but but CC cord-005646-xhx9pzhj 998 13 mainly mainly RB cord-005646-xhx9pzhj 998 14 transient transient JJ cord-005646-xhx9pzhj 998 15 . . . cord-005646-xhx9pzhj 999 1 In in IN cord-005646-xhx9pzhj 999 2 our -PRON- PRP$ cord-005646-xhx9pzhj 999 3 series series NN cord-005646-xhx9pzhj 999 4 , , , cord-005646-xhx9pzhj 999 5 specific specific JJ cord-005646-xhx9pzhj 999 6 CPB CPB NNP cord-005646-xhx9pzhj 999 7 - - HYPH cord-005646-xhx9pzhj 999 8 related relate VBN cord-005646-xhx9pzhj 999 9 parameters parameter NNS cord-005646-xhx9pzhj 999 10 are be VBP cord-005646-xhx9pzhj 999 11 of of IN cord-005646-xhx9pzhj 999 12 greater great JJR cord-005646-xhx9pzhj 999 13 influence influence NN cord-005646-xhx9pzhj 999 14 than than IN cord-005646-xhx9pzhj 999 15 surgical surgical JJ cord-005646-xhx9pzhj 999 16 procedure procedure NN cord-005646-xhx9pzhj 999 17 itseif itseif NNS cord-005646-xhx9pzhj 999 18 for for IN cord-005646-xhx9pzhj 999 19 the the DT cord-005646-xhx9pzhj 999 20 development development NN cord-005646-xhx9pzhj 999 21 of of IN cord-005646-xhx9pzhj 999 22 DR DR NNP cord-005646-xhx9pzhj 999 23 and and CC cord-005646-xhx9pzhj 999 24 are be VBP cord-005646-xhx9pzhj 999 25 discriminant discriminant JJ cord-005646-xhx9pzhj 999 26 risk risk NN cord-005646-xhx9pzhj 999 27 factors factor NNS cord-005646-xhx9pzhj 999 28 for for IN cord-005646-xhx9pzhj 999 29 particular particular JJ cord-005646-xhx9pzhj 999 30 types type NNS cord-005646-xhx9pzhj 999 31 of of IN cord-005646-xhx9pzhj 999 32 DR DR NNP cord-005646-xhx9pzhj 999 33 . . . cord-005646-xhx9pzhj 1000 1 The the DT cord-005646-xhx9pzhj 1000 2 course course NN cord-005646-xhx9pzhj 1000 3 of of IN cord-005646-xhx9pzhj 1000 4 ANP ANP NNP cord-005646-xhx9pzhj 1000 5 , , , cord-005646-xhx9pzhj 1000 6 cGMP cGMP NNP cord-005646-xhx9pzhj 1000 7 / / SYM cord-005646-xhx9pzhj 1000 8 ANP ANP NNP cord-005646-xhx9pzhj 1000 9 ( ( -LRB- cord-005646-xhx9pzhj 1000 10 as as IN cord-005646-xhx9pzhj 1000 11 indicator indicator NN cord-005646-xhx9pzhj 1000 12 for for IN cord-005646-xhx9pzhj 1000 13 atrial atrial JJ cord-005646-xhx9pzhj 1000 14 natriurefic natriurefic NNP cord-005646-xhx9pzhj 1000 15 peptide peptide JJ cord-005646-xhx9pzhj 1000 16 biological biological JJ cord-005646-xhx9pzhj 1000 17 activity activity NN cord-005646-xhx9pzhj 1000 18 ) ) -RRB- cord-005646-xhx9pzhj 1000 19 , , , cord-005646-xhx9pzhj 1000 20 and and CC cord-005646-xhx9pzhj 1000 21 NO2 NO2 NNP cord-005646-xhx9pzhj 1000 22 and and CC cord-005646-xhx9pzhj 1000 23 NO3 NO3 NNP cord-005646-xhx9pzhj 1000 24 ( ( -LRB- cord-005646-xhx9pzhj 1000 25 as as IN cord-005646-xhx9pzhj 1000 26 indicator indicator NN cord-005646-xhx9pzhj 1000 27 for for IN cord-005646-xhx9pzhj 1000 28 endogenous endogenous JJ cord-005646-xhx9pzhj 1000 29 nitric nitric NN cord-005646-xhx9pzhj 1000 30 oxide oxide NN cord-005646-xhx9pzhj 1000 31 ( ( -LRB- cord-005646-xhx9pzhj 1000 32 NO no DT cord-005646-xhx9pzhj 1000 33 ) ) -RRB- cord-005646-xhx9pzhj 1000 34 synthesis synthesis NN cord-005646-xhx9pzhj 1000 35 ) ) -RRB- cord-005646-xhx9pzhj 1000 36 was be VBD cord-005646-xhx9pzhj 1000 37 investigated investigate VBN cord-005646-xhx9pzhj 1000 38 in in IN cord-005646-xhx9pzhj 1000 39 I9 i9 JJ cord-005646-xhx9pzhj 1000 40 infants infant NNS cord-005646-xhx9pzhj 1000 41 ( ( -LRB- cord-005646-xhx9pzhj 1000 42 median median JJ cord-005646-xhx9pzhj 1000 43 age age NN cord-005646-xhx9pzhj 1000 44 4 4 CD cord-005646-xhx9pzhj 1000 45 months month NNS cord-005646-xhx9pzhj 1000 46 ) ) -RRB- cord-005646-xhx9pzhj 1000 47 undergoing undergo VBG cord-005646-xhx9pzhj 1000 48 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 1000 49 bypass bypass NN cord-005646-xhx9pzhj 1000 50 ( ( -LRB- cord-005646-xhx9pzhj 1000 51 CPB CPB NNP cord-005646-xhx9pzhj 1000 52 ) ) -RRB- cord-005646-xhx9pzhj 1000 53 . . . cord-005646-xhx9pzhj 1001 1 Patients patient NNS cord-005646-xhx9pzhj 1001 2 were be VBD cord-005646-xhx9pzhj 1001 3 divided divide VBN cord-005646-xhx9pzhj 1001 4 into into IN cord-005646-xhx9pzhj 1001 5 2 2 CD cord-005646-xhx9pzhj 1001 6 groups group NNS cord-005646-xhx9pzhj 1001 7 according accord VBG cord-005646-xhx9pzhj 1001 8 to to IN cord-005646-xhx9pzhj 1001 9 whether whether IN cord-005646-xhx9pzhj 1001 10 they -PRON- PRP cord-005646-xhx9pzhj 1001 11 had have VBD cord-005646-xhx9pzhj 1001 12 ( ( -LRB- cord-005646-xhx9pzhj 1001 13 group group NN cord-005646-xhx9pzhj 1001 14 1 1 CD cord-005646-xhx9pzhj 1001 15 , , , cord-005646-xhx9pzhj 1001 16 n=13 n=13 NNP cord-005646-xhx9pzhj 1001 17 ) ) -RRB- cord-005646-xhx9pzhj 1001 18 or or CC cord-005646-xhx9pzhj 1001 19 not not RB cord-005646-xhx9pzhj 1001 20 ( ( -LRB- cord-005646-xhx9pzhj 1001 21 group group NN cord-005646-xhx9pzhj 1001 22 2 2 CD cord-005646-xhx9pzhj 1001 23 , , , cord-005646-xhx9pzhj 1001 24 n=6 n=6 JJ cord-005646-xhx9pzhj 1001 25 ) ) -RRB- cord-005646-xhx9pzhj 1002 1 preoperative preoperative JJ cord-005646-xhx9pzhj 1002 2 heart heart NN cord-005646-xhx9pzhj 1002 3 failure failure NN cord-005646-xhx9pzhj 1002 4 ( ( -LRB- cord-005646-xhx9pzhj 1002 5 HF HF NNP cord-005646-xhx9pzhj 1002 6 ) ) -RRB- cord-005646-xhx9pzhj 1002 7 and and CC cord-005646-xhx9pzhj 1002 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1002 9 hypertension hypertension NN cord-005646-xhx9pzhj 1002 10 ( ( -LRB- cord-005646-xhx9pzhj 1002 11 PHT PHT NNP cord-005646-xhx9pzhj 1002 12 ) ) -RRB- cord-005646-xhx9pzhj 1002 13 . . . cord-005646-xhx9pzhj 1003 1 Group group NN cord-005646-xhx9pzhj 1003 2 1 1 CD cord-005646-xhx9pzhj 1003 3 patients patient NNS cord-005646-xhx9pzhj 1003 4 had have VBD cord-005646-xhx9pzhj 1003 5 preoperatively preoperatively RB cord-005646-xhx9pzhj 1003 6 significantly significantly RB cord-005646-xhx9pzhj 1003 7 higher high JJR cord-005646-xhx9pzhj 1003 8 levels level NNS cord-005646-xhx9pzhj 1003 9 of of IN cord-005646-xhx9pzhj 1003 10 ANP ANP NNP cord-005646-xhx9pzhj 1003 11 ( ( -LRB- cord-005646-xhx9pzhj 1003 12 p<0.005 p<0.005 CD cord-005646-xhx9pzhj 1003 13 ) ) -RRB- cord-005646-xhx9pzhj 1003 14 , , , cord-005646-xhx9pzhj 1003 15 cGMP cGMP NNP cord-005646-xhx9pzhj 1003 16 ( ( -LRB- cord-005646-xhx9pzhj 1003 17 p<0.02 p<0.02 NNP cord-005646-xhx9pzhj 1003 18 ) ) -RRB- cord-005646-xhx9pzhj 1003 19 and and CC cord-005646-xhx9pzhj 1003 20 NO2 NO2 NNP cord-005646-xhx9pzhj 1003 21 and and CC cord-005646-xhx9pzhj 1003 22 NO3 NO3 NNP cord-005646-xhx9pzhj 1003 23 ( ( -LRB- cord-005646-xhx9pzhj 1003 24 , , , cord-005646-xhx9pzhj 1003 25 p<0.02 p<0.02 NN cord-005646-xhx9pzhj 1003 26 ) ) -RRB- cord-005646-xhx9pzhj 1003 27 but but CC cord-005646-xhx9pzhj 1003 28 had have VBD cord-005646-xhx9pzhj 1003 29 significantly significantly RB cord-005646-xhx9pzhj 1003 30 lower low JJR cord-005646-xhx9pzhj 1003 31 cGMP cGMP NNP cord-005646-xhx9pzhj 1003 32 / / SYM cord-005646-xhx9pzhj 1003 33 ANP ANP NNP cord-005646-xhx9pzhj 1003 34 ( ( -LRB- cord-005646-xhx9pzhj 1003 35 I0<0.05 I0<0.05 NNP cord-005646-xhx9pzhj 1003 36 ) ) -RRB- cord-005646-xhx9pzhj 1003 37 than than IN cord-005646-xhx9pzhj 1003 38 group group NN cord-005646-xhx9pzhj 1003 39 2 2 CD cord-005646-xhx9pzhj 1003 40 patients patient NNS cord-005646-xhx9pzhj 1003 41 . . . cord-005646-xhx9pzhj 1004 1 During during IN cord-005646-xhx9pzhj 1004 2 CPB CPB NNP cord-005646-xhx9pzhj 1004 3 , , , cord-005646-xhx9pzhj 1004 4 ANP ANP NNP cord-005646-xhx9pzhj 1004 5 was be VBD cord-005646-xhx9pzhj 1004 6 significantly significantly RB cord-005646-xhx9pzhj 1004 7 higher high JJR cord-005646-xhx9pzhj 1004 8 in in IN cord-005646-xhx9pzhj 1004 9 group group NN cord-005646-xhx9pzhj 1004 10 1 1 CD cord-005646-xhx9pzhj 1004 11 patients patient NNS cord-005646-xhx9pzhj 1004 12 ~<0.02 ~<0.02 CD cord-005646-xhx9pzhj 1004 13 ) ) -RRB- cord-005646-xhx9pzhj 1004 14 . . . cord-005646-xhx9pzhj 1005 1 As as IN cord-005646-xhx9pzhj 1005 2 compared compare VBN cord-005646-xhx9pzhj 1005 3 with with IN cord-005646-xhx9pzhj 1005 4 prebypass prebypass NN cord-005646-xhx9pzhj 1005 5 values value NNS cord-005646-xhx9pzhj 1005 6 , , , cord-005646-xhx9pzhj 1005 7 cGMP cGMP NNP cord-005646-xhx9pzhj 1005 8 / / SYM cord-005646-xhx9pzhj 1005 9 ANP ANP NNP cord-005646-xhx9pzhj 1005 10 was be VBD cord-005646-xhx9pzhj 1005 11 reduced reduce VBN cord-005646-xhx9pzhj 1005 12 in in IN cord-005646-xhx9pzhj 1005 13 both both DT cord-005646-xhx9pzhj 1005 14 groups group NNS cord-005646-xhx9pzhj 1005 15 during during IN cord-005646-xhx9pzhj 1005 16 CPB CPB NNP cord-005646-xhx9pzhj 1005 17 ( ( -LRB- cord-005646-xhx9pzhj 1005 18 p<0.0001 p<0.0001 NNP cord-005646-xhx9pzhj 1005 19 ) ) -RRB- cord-005646-xhx9pzhj 1005 20 . . . cord-005646-xhx9pzhj 1006 1 cGMP cGMP NNP cord-005646-xhx9pzhj 1006 2 / / SYM cord-005646-xhx9pzhj 1006 3 ANP ANP NNP cord-005646-xhx9pzhj 1006 4 inversely inversely RB cord-005646-xhx9pzhj 1006 5 correlated correlate VBD cord-005646-xhx9pzhj 1006 6 with with IN cord-005646-xhx9pzhj 1006 7 duration duration NN cord-005646-xhx9pzhj 1006 8 of of IN cord-005646-xhx9pzhj 1006 9 CPB CPB NNP cord-005646-xhx9pzhj 1006 10 and and CC cord-005646-xhx9pzhj 1006 11 aortic aortic JJ cord-005646-xhx9pzhj 1006 12 clamping clamp VBG cord-005646-xhx9pzhj 1006 13 time time NN cord-005646-xhx9pzhj 1006 14 ( ( -LRB- cord-005646-xhx9pzhj 1006 15 p<0.001 p<0.001 NNS cord-005646-xhx9pzhj 1006 16 , , , cord-005646-xhx9pzhj 1006 17 respectively respectively RB cord-005646-xhx9pzhj 1006 18 ) ) -RRB- cord-005646-xhx9pzhj 1006 19 . . . cord-005646-xhx9pzhj 1007 1 NO2 NO2 NNP cord-005646-xhx9pzhj 1007 2 and and CC cord-005646-xhx9pzhj 1007 3 NO3 NO3 NNP cord-005646-xhx9pzhj 1007 4 were be VBD cord-005646-xhx9pzhj 1007 5 significantly significantly RB cord-005646-xhx9pzhj 1007 6 higher high JJR cord-005646-xhx9pzhj 1007 7 in in IN cord-005646-xhx9pzhj 1007 8 group group NN cord-005646-xhx9pzhj 1007 9 1 1 CD cord-005646-xhx9pzhj 1007 10 than than IN cord-005646-xhx9pzhj 1007 11 in in IN cord-005646-xhx9pzhj 1007 12 group group NN cord-005646-xhx9pzhj 1007 13 2 2 CD cord-005646-xhx9pzhj 1007 14 patients patient NNS cord-005646-xhx9pzhj 1007 15 ( ( -LRB- cord-005646-xhx9pzhj 1007 16 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1007 17 ) ) -RRB- cord-005646-xhx9pzhj 1007 18 without without IN cord-005646-xhx9pzhj 1007 19 any any DT cord-005646-xhx9pzhj 1007 20 intraindividual intraindividual FW cord-005646-xhx9pzhj 1007 21 change change NN cord-005646-xhx9pzhj 1007 22 during during IN cord-005646-xhx9pzhj 1007 23 CPB CPB NNP cord-005646-xhx9pzhj 1007 24 . . . cord-005646-xhx9pzhj 1008 1 From from IN cord-005646-xhx9pzhj 1008 2 the the DT cord-005646-xhx9pzhj 1008 3 early early JJ cord-005646-xhx9pzhj 1008 4 postoperative postoperative JJ cord-005646-xhx9pzhj 1008 5 period period NN cord-005646-xhx9pzhj 1008 6 on on IN cord-005646-xhx9pzhj 1008 7 ANP ANP NNP cord-005646-xhx9pzhj 1008 8 , , , cord-005646-xhx9pzhj 1008 9 cGMP cGMP NNP cord-005646-xhx9pzhj 1008 10 / / SYM cord-005646-xhx9pzhj 1008 11 ANP ANP NNP cord-005646-xhx9pzhj 1008 12 and and CC cord-005646-xhx9pzhj 1008 13 NO2 NO2 NNP cord-005646-xhx9pzhj 1008 14 and and CC cord-005646-xhx9pzhj 1008 15 NO3 NO3 NNP cord-005646-xhx9pzhj 1008 16 were be VBD cord-005646-xhx9pzhj 1008 17 similar similar JJ cord-005646-xhx9pzhj 1008 18 in in IN cord-005646-xhx9pzhj 1008 19 both both DT cord-005646-xhx9pzhj 1008 20 groups group NNS cord-005646-xhx9pzhj 1008 21 . . . cord-005646-xhx9pzhj 1009 1 After after IN cord-005646-xhx9pzhj 1009 2 CPB CPB NNP cord-005646-xhx9pzhj 1009 3 , , , cord-005646-xhx9pzhj 1009 4 ANP ANP NNP cord-005646-xhx9pzhj 1009 5 correlated correlate VBD cord-005646-xhx9pzhj 1009 6 in in IN cord-005646-xhx9pzhj 1009 7 both both DT cord-005646-xhx9pzhj 1009 8 groups group NNS cord-005646-xhx9pzhj 1009 9 with with IN cord-005646-xhx9pzhj 1009 10 blood blood NN cord-005646-xhx9pzhj 1009 11 pressure pressure NN cord-005646-xhx9pzhj 1009 12 ( ( -LRB- cord-005646-xhx9pzhj 1009 13 p<0,001 p<0,001 NNP cord-005646-xhx9pzhj 1009 14 ) ) -RRB- cord-005646-xhx9pzhj 1009 15 and and CC cord-005646-xhx9pzhj 1009 16 diuresis diuresis NN cord-005646-xhx9pzhj 1009 17 ( ( -LRB- cord-005646-xhx9pzhj 1009 18 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1009 19 ) ) -RRB- cord-005646-xhx9pzhj 1009 20 . . . cord-005646-xhx9pzhj 1010 1 NO2 NO2 NNP cord-005646-xhx9pzhj 1010 2 and and CC cord-005646-xhx9pzhj 1010 3 NO3 NO3 NNP cord-005646-xhx9pzhj 1010 4 inversely inversely RB cord-005646-xhx9pzhj 1010 5 correlated correlate VBD cord-005646-xhx9pzhj 1010 6 with with IN cord-005646-xhx9pzhj 1010 7 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1010 8 arterial arterial JJ cord-005646-xhx9pzhj 1010 9 pressure pressure NN cord-005646-xhx9pzhj 1010 10 immediately immediately RB cord-005646-xhx9pzhj 1010 11 after after IN cord-005646-xhx9pzhj 1010 12 CPB CPB NNP cord-005646-xhx9pzhj 1010 13 ( ( -LRB- cord-005646-xhx9pzhj 1010 14 19<0.05 19<0.05 CD cord-005646-xhx9pzhj 1010 15 Patients patient NNS cord-005646-xhx9pzhj 1010 16 after after IN cord-005646-xhx9pzhj 1010 17 a a DT cord-005646-xhx9pzhj 1010 18 Fontan Fontan NNP cord-005646-xhx9pzhj 1010 19 - - HYPH cord-005646-xhx9pzhj 1010 20 type type NN cord-005646-xhx9pzhj 1010 21 of of IN cord-005646-xhx9pzhj 1010 22 procedure procedure NN cord-005646-xhx9pzhj 1010 23 have have VBP cord-005646-xhx9pzhj 1010 24 elevated elevate VBN cord-005646-xhx9pzhj 1010 25 central central JJ cord-005646-xhx9pzhj 1010 26 venous venous JJ cord-005646-xhx9pzhj 1010 27 pressures pressure NNS cord-005646-xhx9pzhj 1010 28 ( ( -LRB- cord-005646-xhx9pzhj 1010 29 cvp cvp NNP cord-005646-xhx9pzhj 1010 30 ) ) -RRB- cord-005646-xhx9pzhj 1010 31 leading lead VBG cord-005646-xhx9pzhj 1010 32 to to IN cord-005646-xhx9pzhj 1010 33 congestion congestion NN cord-005646-xhx9pzhj 1010 34 in in IN cord-005646-xhx9pzhj 1010 35 the the DT cord-005646-xhx9pzhj 1010 36 gastrointestinal gastrointestinal JJ cord-005646-xhx9pzhj 1010 37 system system NN cord-005646-xhx9pzhj 1010 38 and and CC cord-005646-xhx9pzhj 1010 39 often often RB cord-005646-xhx9pzhj 1010 40 ascites ascite VBZ cord-005646-xhx9pzhj 1010 41 . . . cord-005646-xhx9pzhj 1011 1 Purpose purpose NN cord-005646-xhx9pzhj 1011 2 of of IN cord-005646-xhx9pzhj 1011 3 this this DT cord-005646-xhx9pzhj 1011 4 study study NN cord-005646-xhx9pzhj 1011 5 was be VBD cord-005646-xhx9pzhj 1011 6 to to TO cord-005646-xhx9pzhj 1011 7 evaluate evaluate VB cord-005646-xhx9pzhj 1011 8 whether whether IN cord-005646-xhx9pzhj 1011 9 this this DT cord-005646-xhx9pzhj 1011 10 causes cause VBZ cord-005646-xhx9pzhj 1011 11 a a DT cord-005646-xhx9pzhj 1011 12 different different JJ cord-005646-xhx9pzhj 1011 13 postoperative postoperative JJ cord-005646-xhx9pzhj 1011 14 gastric gastric JJ cord-005646-xhx9pzhj 1011 15 mucosal mucosal JJ cord-005646-xhx9pzhj 1011 16 pH ph NN cord-005646-xhx9pzhj 1011 17 ( ( -LRB- cord-005646-xhx9pzhj 1011 18 pHi pHi NNP cord-005646-xhx9pzhj 1011 19 ) ) -RRB- cord-005646-xhx9pzhj 1011 20 . . . cord-005646-xhx9pzhj 1012 1 Methods method NNS cord-005646-xhx9pzhj 1012 2 : : : cord-005646-xhx9pzhj 1013 1 We -PRON- PRP cord-005646-xhx9pzhj 1013 2 evaluated evaluate VBD cord-005646-xhx9pzhj 1013 3 a a DT cord-005646-xhx9pzhj 1013 4 series series NN cord-005646-xhx9pzhj 1013 5 of of IN cord-005646-xhx9pzhj 1013 6 35 35 CD cord-005646-xhx9pzhj 1013 7 patients patient NNS cord-005646-xhx9pzhj 1013 8 , , , cord-005646-xhx9pzhj 1013 9 who who WP cord-005646-xhx9pzhj 1013 10 underwent undergo VBD cord-005646-xhx9pzhj 1013 11 cardiac cardiac JJ cord-005646-xhx9pzhj 1013 12 surgery surgery NN cord-005646-xhx9pzhj 1013 13 with with IN cord-005646-xhx9pzhj 1013 14 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 1013 15 bypass bypass NN cord-005646-xhx9pzhj 1013 16 ( ( -LRB- cord-005646-xhx9pzhj 1013 17 age age NN cord-005646-xhx9pzhj 1013 18 : : : cord-005646-xhx9pzhj 1013 19 5 5 CD cord-005646-xhx9pzhj 1013 20 days day NNS cord-005646-xhx9pzhj 1013 21 to to IN cord-005646-xhx9pzhj 1013 22 16 16 CD cord-005646-xhx9pzhj 1013 23 years year NNS cord-005646-xhx9pzhj 1013 24 ( ( -LRB- cord-005646-xhx9pzhj 1013 25 mean mean VBP cord-005646-xhx9pzhj 1013 26 2,2 2,2 CD cord-005646-xhx9pzhj 1013 27 yrs yr NNS cord-005646-xhx9pzhj 1013 28 ) ) -RRB- cord-005646-xhx9pzhj 1013 29 , , , cord-005646-xhx9pzhj 1013 30 weight weight NN cord-005646-xhx9pzhj 1013 31 : : : cord-005646-xhx9pzhj 1013 32 3.2 3.2 CD cord-005646-xhx9pzhj 1013 33 to to IN cord-005646-xhx9pzhj 1013 34 37 37 CD cord-005646-xhx9pzhj 1013 35 kg kg NNS cord-005646-xhx9pzhj 1013 36 ( ( -LRB- cord-005646-xhx9pzhj 1013 37 mean mean VB cord-005646-xhx9pzhj 1013 38 10.2 10.2 CD cord-005646-xhx9pzhj 1013 39 kg kg NNS cord-005646-xhx9pzhj 1013 40 ) ) -RRB- cord-005646-xhx9pzhj 1013 41 . . . cord-005646-xhx9pzhj 1014 1 A a DT cord-005646-xhx9pzhj 1014 2 commercially commercially RB cord-005646-xhx9pzhj 1014 3 available available JJ cord-005646-xhx9pzhj 1014 4 tonometer tonometer NN cord-005646-xhx9pzhj 1014 5 ( ( -LRB- cord-005646-xhx9pzhj 1014 6 Tonometics Tonometics NNP cord-005646-xhx9pzhj 1014 7 ® ® VBP cord-005646-xhx9pzhj 1014 8 ) ) -RRB- cord-005646-xhx9pzhj 1014 9 for for IN cord-005646-xhx9pzhj 1014 10 sigmoidal sigmoidal JJ cord-005646-xhx9pzhj 1014 11 use use NN cord-005646-xhx9pzhj 1014 12 in in IN cord-005646-xhx9pzhj 1014 13 adults adult NNS cord-005646-xhx9pzhj 1014 14 was be VBD cord-005646-xhx9pzhj 1014 15 inserted insert VBN cord-005646-xhx9pzhj 1014 16 into into IN cord-005646-xhx9pzhj 1014 17 the the DT cord-005646-xhx9pzhj 1014 18 stomach stomach NN cord-005646-xhx9pzhj 1014 19 after after IN cord-005646-xhx9pzhj 1014 20 induction induction NN cord-005646-xhx9pzhj 1014 21 of of IN cord-005646-xhx9pzhj 1014 22 anesthesia anesthesia NN cord-005646-xhx9pzhj 1014 23 . . . cord-005646-xhx9pzhj 1015 1 The the DT cord-005646-xhx9pzhj 1015 2 pHi phi JJ cord-005646-xhx9pzhj 1015 3 measurements measurement NNS cord-005646-xhx9pzhj 1015 4 were be VBD cord-005646-xhx9pzhj 1015 5 done do VBN cord-005646-xhx9pzhj 1015 6 according accord VBG cord-005646-xhx9pzhj 1015 7 to to IN cord-005646-xhx9pzhj 1015 8 manufacturer manufacturer NN cord-005646-xhx9pzhj 1015 9 recommendations recommendation NNS cord-005646-xhx9pzhj 1016 1 We -PRON- PRP cord-005646-xhx9pzhj 1016 2 compared compare VBD cord-005646-xhx9pzhj 1016 3 three three CD cord-005646-xhx9pzhj 1016 4 groups group NNS cord-005646-xhx9pzhj 1016 5 of of IN cord-005646-xhx9pzhj 1016 6 patients patient NNS cord-005646-xhx9pzhj 1016 7 : : : cord-005646-xhx9pzhj 1016 8 1 1 LS cord-005646-xhx9pzhj 1016 9 ) ) -RRB- cord-005646-xhx9pzhj 1016 10 aeyanotic aeyanotic NNP cord-005646-xhx9pzhj 1016 11 ( ( -LRB- cord-005646-xhx9pzhj 1016 12 n=20 n=20 NNP cord-005646-xhx9pzhj 1016 13 ) ) -RRB- cord-005646-xhx9pzhj 1016 14 , , , cord-005646-xhx9pzhj 1016 15 among among IN cord-005646-xhx9pzhj 1016 16 them -PRON- PRP cord-005646-xhx9pzhj 1016 17 9 9 CD cord-005646-xhx9pzhj 1016 18 P p NN cord-005646-xhx9pzhj 1016 19 with with IN cord-005646-xhx9pzhj 1016 20 VSD VSD NNP cord-005646-xhx9pzhj 1016 21 and and CC cord-005646-xhx9pzhj 1016 22 5 5 CD cord-005646-xhx9pzhj 1016 23 P p NN cord-005646-xhx9pzhj 1016 24 with with IN cord-005646-xhx9pzhj 1016 25 AVSD AVSD NNP cord-005646-xhx9pzhj 1016 26 ; ; : cord-005646-xhx9pzhj 1016 27 2 2 LS cord-005646-xhx9pzhj 1016 28 ) ) -RRB- cord-005646-xhx9pzhj 1016 29 cyanotic cyanotic JJ cord-005646-xhx9pzhj 1016 30 ( ( -LRB- cord-005646-xhx9pzhj 1016 31 n=10 n=10 NNP cord-005646-xhx9pzhj 1016 32 ) ) -RRB- cord-005646-xhx9pzhj 1016 33 : : : cord-005646-xhx9pzhj 1016 34 TOF TOF NNP cord-005646-xhx9pzhj 1016 35 : : : cord-005646-xhx9pzhj 1016 36 6P 6p CD cord-005646-xhx9pzhj 1016 37 , , , cord-005646-xhx9pzhj 1016 38 TGA TGA NNP cord-005646-xhx9pzhj 1016 39 : : : cord-005646-xhx9pzhj 1016 40 4P 4p NN cord-005646-xhx9pzhj 1016 41 ; ; : cord-005646-xhx9pzhj 1016 42 3 3 CD cord-005646-xhx9pzhj 1016 43 ) ) -RRB- cord-005646-xhx9pzhj 1016 44 cyanotic cyanotic JJ cord-005646-xhx9pzhj 1016 45 after after IN cord-005646-xhx9pzhj 1016 46 a a DT cord-005646-xhx9pzhj 1016 47 Fontan Fontan NNP cord-005646-xhx9pzhj 1016 48 - - HYPH cord-005646-xhx9pzhj 1016 49 type type NN cord-005646-xhx9pzhj 1016 50 procedure procedure NN cord-005646-xhx9pzhj 1016 51 ( ( -LRB- cord-005646-xhx9pzhj 1016 52 n=5 n=5 NNP cord-005646-xhx9pzhj 1016 53 ) ) -RRB- cord-005646-xhx9pzhj 1016 54 . . . cord-005646-xhx9pzhj 1017 1 Phi Phi NNP cord-005646-xhx9pzhj 1017 2 were be VBD cord-005646-xhx9pzhj 1017 3 measured measure VBN cord-005646-xhx9pzhj 1017 4 at at IN cord-005646-xhx9pzhj 1017 5 PICU PICU NNP cord-005646-xhx9pzhj 1017 6 arrival arrival NN cord-005646-xhx9pzhj 1017 7 and and CC cord-005646-xhx9pzhj 1017 8 after after IN cord-005646-xhx9pzhj 1017 9 6h 6h CD cord-005646-xhx9pzhj 1017 10 . . . cord-005646-xhx9pzhj 1018 1 Fudhermore Fudhermore NNP cord-005646-xhx9pzhj 1018 2 we -PRON- PRP cord-005646-xhx9pzhj 1018 3 compared compare VBD cord-005646-xhx9pzhj 1018 4 lactat lactat NN cord-005646-xhx9pzhj 1018 5 levels level NNS cord-005646-xhx9pzhj 1018 6 at at IN cord-005646-xhx9pzhj 1018 7 these these DT cord-005646-xhx9pzhj 1018 8 time time NN cord-005646-xhx9pzhj 1018 9 points point NNS cord-005646-xhx9pzhj 1018 10 . . . cord-005646-xhx9pzhj 1019 1 Differences difference NNS cord-005646-xhx9pzhj 1019 2 between between IN cord-005646-xhx9pzhj 1019 3 the the DT cord-005646-xhx9pzhj 1019 4 groups group NNS cord-005646-xhx9pzhj 1019 5 were be VBD cord-005646-xhx9pzhj 1019 6 evaluated evaluate VBN cord-005646-xhx9pzhj 1019 7 with with IN cord-005646-xhx9pzhj 1019 8 one one CD cord-005646-xhx9pzhj 1019 9 way way NN cord-005646-xhx9pzhj 1019 10 ANOVA ANOVA NNP cord-005646-xhx9pzhj 1019 11 on on IN cord-005646-xhx9pzhj 1019 12 ranks rank NNS cord-005646-xhx9pzhj 1019 13 with with IN cord-005646-xhx9pzhj 1019 14 pairwaise pairwaise JJ cord-005646-xhx9pzhj 1019 15 multiple multiple JJ cord-005646-xhx9pzhj 1019 16 comparisons comparison NNS cord-005646-xhx9pzhj 1019 17 ( ( -LRB- cord-005646-xhx9pzhj 1019 18 Dunn Dunn NNP cord-005646-xhx9pzhj 1019 19 's 's POS cord-005646-xhx9pzhj 1019 20 method method NN cord-005646-xhx9pzhj 1019 21 ) ) -RRB- cord-005646-xhx9pzhj 1019 22 . . . cord-005646-xhx9pzhj 1020 1 The the DT cord-005646-xhx9pzhj 1020 2 relationship relationship NN cord-005646-xhx9pzhj 1020 3 between between IN cord-005646-xhx9pzhj 1020 4 CVP CVP NNP cord-005646-xhx9pzhj 1020 5 and and CC cord-005646-xhx9pzhj 1020 6 pHi pHi NNS cord-005646-xhx9pzhj 1020 7 was be VBD cord-005646-xhx9pzhj 1020 8 investigated investigate VBN cord-005646-xhx9pzhj 1020 9 by by IN cord-005646-xhx9pzhj 1020 10 regression regression NN cord-005646-xhx9pzhj 1020 11 analysis analysis NN cord-005646-xhx9pzhj 1020 12 . . . cord-005646-xhx9pzhj 1021 1 Results result NNS cord-005646-xhx9pzhj 1021 2 : : : cord-005646-xhx9pzhj 1022 1 The the DT cord-005646-xhx9pzhj 1022 2 median median JJ cord-005646-xhx9pzhj 1022 3 pHi pHi NNS cord-005646-xhx9pzhj 1022 4 for for IN cord-005646-xhx9pzhj 1022 5 groups group NNS cord-005646-xhx9pzhj 1022 6 I -PRON- PRP cord-005646-xhx9pzhj 1022 7 , , , cord-005646-xhx9pzhj 1022 8 2 2 CD cord-005646-xhx9pzhj 1022 9 and and CC cord-005646-xhx9pzhj 1022 10 3 3 CD cord-005646-xhx9pzhj 1022 11 were be VBD cord-005646-xhx9pzhj 1022 12 7.28 7.28 CD cord-005646-xhx9pzhj 1022 13 , , , cord-005646-xhx9pzhj 1022 14 7.27 7.27 CD cord-005646-xhx9pzhj 1022 15 and and CC cord-005646-xhx9pzhj 1022 16 7.13 7.13 CD cord-005646-xhx9pzhj 1022 17 at at IN cord-005646-xhx9pzhj 1022 18 ardval ardval NNP cord-005646-xhx9pzhj 1022 19 and and CC cord-005646-xhx9pzhj 1022 20 7.30 7.30 CD cord-005646-xhx9pzhj 1022 21 , , , cord-005646-xhx9pzhj 1022 22 7.25 7.25 CD cord-005646-xhx9pzhj 1022 23 and and CC cord-005646-xhx9pzhj 1022 24 7.21 7.21 CD cord-005646-xhx9pzhj 1022 25 after after IN cord-005646-xhx9pzhj 1022 26 6h 6h CD cord-005646-xhx9pzhj 1022 27 respectively respectively RB cord-005646-xhx9pzhj 1022 28 . . . cord-005646-xhx9pzhj 1023 1 At at IN cord-005646-xhx9pzhj 1023 2 PICU PICU NNP cord-005646-xhx9pzhj 1023 3 arrival arrival NN cord-005646-xhx9pzhj 1023 4 group group NN cord-005646-xhx9pzhj 1023 5 3 3 CD cord-005646-xhx9pzhj 1023 6 was be VBD cord-005646-xhx9pzhj 1023 7 significantly significantly RB cord-005646-xhx9pzhj 1023 8 ( ( -LRB- cord-005646-xhx9pzhj 1023 9 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1023 10 ) ) -RRB- cord-005646-xhx9pzhj 1024 1 different different JJ cord-005646-xhx9pzhj 1024 2 from from IN cord-005646-xhx9pzhj 1024 3 groups group NNS cord-005646-xhx9pzhj 1024 4 1 1 CD cord-005646-xhx9pzhj 1024 5 and and CC cord-005646-xhx9pzhj 1024 6 2 2 CD cord-005646-xhx9pzhj 1024 7 . . . cord-005646-xhx9pzhj 1025 1 There there EX cord-005646-xhx9pzhj 1025 2 was be VBD cord-005646-xhx9pzhj 1025 3 no no DT cord-005646-xhx9pzhj 1025 4 significant significant JJ cord-005646-xhx9pzhj 1025 5 difference difference NN cord-005646-xhx9pzhj 1025 6 between between IN cord-005646-xhx9pzhj 1025 7 the the DT cord-005646-xhx9pzhj 1025 8 latter latter JJ cord-005646-xhx9pzhj 1025 9 two two CD cord-005646-xhx9pzhj 1025 10 groups group NNS cord-005646-xhx9pzhj 1025 11 , , , cord-005646-xhx9pzhj 1025 12 After after IN cord-005646-xhx9pzhj 1025 13 6h 6h CD cord-005646-xhx9pzhj 1025 14 group group NN cord-005646-xhx9pzhj 1025 15 1 1 CD cord-005646-xhx9pzhj 1025 16 was be VBD cord-005646-xhx9pzhj 1025 17 different different JJ cord-005646-xhx9pzhj 1025 18 from from IN cord-005646-xhx9pzhj 1025 19 group group NN cord-005646-xhx9pzhj 1025 20 3 3 CD cord-005646-xhx9pzhj 1025 21 , , , cord-005646-xhx9pzhj 1025 22 there there EX cord-005646-xhx9pzhj 1025 23 were be VBD cord-005646-xhx9pzhj 1025 24 no no DT cord-005646-xhx9pzhj 1025 25 other other JJ cord-005646-xhx9pzhj 1025 26 significant significant JJ cord-005646-xhx9pzhj 1025 27 differences difference NNS cord-005646-xhx9pzhj 1025 28 . . . cord-005646-xhx9pzhj 1026 1 The the DT cord-005646-xhx9pzhj 1026 2 median median JJ cord-005646-xhx9pzhj 1026 3 lactate lactate NN cord-005646-xhx9pzhj 1026 4 levels level NNS cord-005646-xhx9pzhj 1026 5 for for IN cord-005646-xhx9pzhj 1026 6 groups group NNS cord-005646-xhx9pzhj 1026 7 t t NN cord-005646-xhx9pzhj 1026 8 , , , cord-005646-xhx9pzhj 1026 9 2 2 CD cord-005646-xhx9pzhj 1026 10 and and CC cord-005646-xhx9pzhj 1026 11 3 3 CD cord-005646-xhx9pzhj 1026 12 were be VBD cord-005646-xhx9pzhj 1026 13 2.2 2.2 CD cord-005646-xhx9pzhj 1026 14 , , , cord-005646-xhx9pzhj 1026 15 3,2 3,2 CD cord-005646-xhx9pzhj 1026 16 and and CC cord-005646-xhx9pzhj 1026 17 4.1 4.1 CD cord-005646-xhx9pzhj 1026 18 at at IN cord-005646-xhx9pzhj 1026 19 ardval ardval NN cord-005646-xhx9pzhj 1026 20 and and CC cord-005646-xhx9pzhj 1026 21 1.6 1.6 CD cord-005646-xhx9pzhj 1026 22 , , , cord-005646-xhx9pzhj 1026 23 3.1 3.1 CD cord-005646-xhx9pzhj 1026 24 and and CC cord-005646-xhx9pzhj 1026 25 3.3 3.3 CD cord-005646-xhx9pzhj 1026 26 after after IN cord-005646-xhx9pzhj 1026 27 6h 6h CD cord-005646-xhx9pzhj 1026 28 respectively respectively RB cord-005646-xhx9pzhj 1026 29 . . . cord-005646-xhx9pzhj 1027 1 At at IN cord-005646-xhx9pzhj 1027 2 PtCU PtCU NNP cord-005646-xhx9pzhj 1027 3 arrival arrival NN cord-005646-xhx9pzhj 1027 4 group group NN cord-005646-xhx9pzhj 1027 5 3 3 CD cord-005646-xhx9pzhj 1027 6 was be VBD cord-005646-xhx9pzhj 1027 7 significantly significantly RB cord-005646-xhx9pzhj 1027 8 ( ( -LRB- cord-005646-xhx9pzhj 1027 9 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1027 10 ) ) -RRB- cord-005646-xhx9pzhj 1028 1 different different JJ cord-005646-xhx9pzhj 1028 2 from from IN cord-005646-xhx9pzhj 1028 3 group group NN cord-005646-xhx9pzhj 1028 4 1 1 CD cord-005646-xhx9pzhj 1028 5 , , , cord-005646-xhx9pzhj 1028 6 after after IN cord-005646-xhx9pzhj 1028 7 6h 6h NNP cord-005646-xhx9pzhj 1028 8 there there EX cord-005646-xhx9pzhj 1028 9 were be VBD cord-005646-xhx9pzhj 1028 10 no no DT cord-005646-xhx9pzhj 1028 11 significant significant JJ cord-005646-xhx9pzhj 1028 12 differences difference NNS cord-005646-xhx9pzhj 1028 13 . . . cord-005646-xhx9pzhj 1029 1 There there EX cord-005646-xhx9pzhj 1029 2 was be VBD cord-005646-xhx9pzhj 1029 3 a a DT cord-005646-xhx9pzhj 1029 4 weak weak JJ cord-005646-xhx9pzhj 1029 5 negative negative JJ cord-005646-xhx9pzhj 1029 6 correlation correlation NN cord-005646-xhx9pzhj 1029 7 between between IN cord-005646-xhx9pzhj 1029 8 cvp cvp NNP cord-005646-xhx9pzhj 1029 9 and and CC cord-005646-xhx9pzhj 1030 1 pHi pHi NNPS cord-005646-xhx9pzhj 1030 2 : : : cord-005646-xhx9pzhj 1030 3 r= r= JJ cord-005646-xhx9pzhj 1030 4 -0.21 -0.21 NNS cord-005646-xhx9pzhj 1030 5 ; ; : cord-005646-xhx9pzhj 1030 6 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1030 7 . . . cord-005646-xhx9pzhj 1031 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1031 2 : : : cord-005646-xhx9pzhj 1031 3 Patients patient NNS cord-005646-xhx9pzhj 1031 4 after after IN cord-005646-xhx9pzhj 1031 5 a a DT cord-005646-xhx9pzhj 1031 6 Fontan Fontan NNP cord-005646-xhx9pzhj 1031 7 - - HYPH cord-005646-xhx9pzhj 1031 8 type type NN cord-005646-xhx9pzhj 1031 9 of of IN cord-005646-xhx9pzhj 1031 10 procedure procedure NN cord-005646-xhx9pzhj 1031 11 have have VBP cord-005646-xhx9pzhj 1031 12 lower low JJR cord-005646-xhx9pzhj 1031 13 pHi pHi NNS cord-005646-xhx9pzhj 1031 14 than than IN cord-005646-xhx9pzhj 1031 15 patients patient NNS cord-005646-xhx9pzhj 1031 16 after after IN cord-005646-xhx9pzhj 1031 17 other other JJ cord-005646-xhx9pzhj 1031 18 cardiac cardiac JJ cord-005646-xhx9pzhj 1031 19 surgical surgical JJ cord-005646-xhx9pzhj 1031 20 procedures procedure NNS cord-005646-xhx9pzhj 1031 21 , , , cord-005646-xhx9pzhj 1031 22 However however RB cord-005646-xhx9pzhj 1031 23 , , , cord-005646-xhx9pzhj 1031 24 this this DT cord-005646-xhx9pzhj 1031 25 is be VBZ cord-005646-xhx9pzhj 1031 26 only only RB cord-005646-xhx9pzhj 1031 27 in in IN cord-005646-xhx9pzhj 1031 28 part part NN cord-005646-xhx9pzhj 1031 29 due due IN cord-005646-xhx9pzhj 1031 30 to to IN cord-005646-xhx9pzhj 1031 31 the the DT cord-005646-xhx9pzhj 1031 32 elevated elevated JJ cord-005646-xhx9pzhj 1031 33 cvp cvp NN cord-005646-xhx9pzhj 1031 34 and and CC cord-005646-xhx9pzhj 1031 35 venous venous JJ cord-005646-xhx9pzhj 1031 36 congestion congestion NN cord-005646-xhx9pzhj 1031 37 . . . cord-005646-xhx9pzhj 1032 1 Eleven eleven CD cord-005646-xhx9pzhj 1032 2 children child NNS cord-005646-xhx9pzhj 1032 3 were be VBD cord-005646-xhx9pzhj 1032 4 investigated investigate VBN cord-005646-xhx9pzhj 1032 5 32 32 CD cord-005646-xhx9pzhj 1032 6 months month NNS cord-005646-xhx9pzhj 1032 7 ( ( -LRB- cord-005646-xhx9pzhj 1032 8 median median NN cord-005646-xhx9pzhj 1032 9 ) ) -RRB- cord-005646-xhx9pzhj 1032 10 after after IN cord-005646-xhx9pzhj 1032 11 postoperative postoperative JJ cord-005646-xhx9pzhj 1032 12 MOF MOF NNP cord-005646-xhx9pzhj 1032 13 . . . cord-005646-xhx9pzhj 1033 1 IVIOF IVIOF NNP cord-005646-xhx9pzhj 1033 2 was be VBD cord-005646-xhx9pzhj 1033 3 defined define VBN cord-005646-xhx9pzhj 1033 4 as as IN cord-005646-xhx9pzhj 1033 5 the the DT cord-005646-xhx9pzhj 1033 6 failure failure NN cord-005646-xhx9pzhj 1033 7 of of IN cord-005646-xhx9pzhj 1033 8 at at RB cord-005646-xhx9pzhj 1033 9 least least RBS cord-005646-xhx9pzhj 1033 10 two two CD cord-005646-xhx9pzhj 1033 11 vital vital JJ cord-005646-xhx9pzhj 1033 12 organ organ NN cord-005646-xhx9pzhj 1033 13 systems system NNS cord-005646-xhx9pzhj 1033 14 ( ( -LRB- cord-005646-xhx9pzhj 1033 15 kidney kidney NN cord-005646-xhx9pzhj 1033 16 , , , cord-005646-xhx9pzhj 1033 17 liver liver NN cord-005646-xhx9pzhj 1033 18 , , , cord-005646-xhx9pzhj 1033 19 lung lung NN cord-005646-xhx9pzhj 1033 20 , , , cord-005646-xhx9pzhj 1033 21 central central JJ cord-005646-xhx9pzhj 1033 22 nervous nervous JJ cord-005646-xhx9pzhj 1033 23 system system NN cord-005646-xhx9pzhj 1033 24 ) ) -RRB- cord-005646-xhx9pzhj 1033 25 in in IN cord-005646-xhx9pzhj 1033 26 addition addition NN cord-005646-xhx9pzhj 1033 27 to to IN cord-005646-xhx9pzhj 1033 28 cardiac cardiac JJ cord-005646-xhx9pzhj 1033 29 insufficiency insufficiency NN cord-005646-xhx9pzhj 1033 30 and and CC cord-005646-xhx9pzhj 1033 31 high high JJ cord-005646-xhx9pzhj 1033 32 fever fever NN cord-005646-xhx9pzhj 1033 33 . . . cord-005646-xhx9pzhj 1034 1 Underlying underlie VBG cord-005646-xhx9pzhj 1034 2 surgical surgical JJ cord-005646-xhx9pzhj 1034 3 procedure procedure NN cord-005646-xhx9pzhj 1034 4 was be VBD cord-005646-xhx9pzhj 1034 5 repair repair NN cord-005646-xhx9pzhj 1034 6 of of IN cord-005646-xhx9pzhj 1034 7 Tetralogy Tetralogy NNP cord-005646-xhx9pzhj 1034 8 of of IN cord-005646-xhx9pzhj 1034 9 Fallot Fallot NNP cord-005646-xhx9pzhj 1034 10 ( ( -LRB- cord-005646-xhx9pzhj 1034 11 n=3 n=3 NN cord-005646-xhx9pzhj 1034 12 ) ) -RRB- cord-005646-xhx9pzhj 1034 13 , , , cord-005646-xhx9pzhj 1034 14 Fontan-(n=7 Fontan-(n=7 NNP cord-005646-xhx9pzhj 1034 15 ) ) -RRB- cord-005646-xhx9pzhj 1034 16 or or CC cord-005646-xhx9pzhj 1034 17 Seuning Seuning NNP cord-005646-xhx9pzhj 1034 18 procedure procedure NN cord-005646-xhx9pzhj 1035 1 ( ( -LRB- cord-005646-xhx9pzhj 1035 2 n n NN cord-005646-xhx9pzhj 1035 3 = = NN cord-005646-xhx9pzhj 1035 4 l l NN cord-005646-xhx9pzhj 1035 5 ) ) -RRB- cord-005646-xhx9pzhj 1035 6 . . . cord-005646-xhx9pzhj 1036 1 All all DT cord-005646-xhx9pzhj 1036 2 patients patient NNS cord-005646-xhx9pzhj 1036 3 fulfilled fulfil VBD cord-005646-xhx9pzhj 1036 4 criteria criterion NNS cord-005646-xhx9pzhj 1036 5 for for IN cord-005646-xhx9pzhj 1036 6 MOF MOF NNP cord-005646-xhx9pzhj 1036 7 in in IN cord-005646-xhx9pzhj 1036 8 the the DT cord-005646-xhx9pzhj 1036 9 3 3 CD cord-005646-xhx9pzhj 1036 10 first first JJ cord-005646-xhx9pzhj 1036 11 postoperative postoperative NN cord-005646-xhx9pzhj 1036 12 ( ( -LRB- cord-005646-xhx9pzhj 1036 13 PO po NN cord-005646-xhx9pzhj 1036 14 ) ) -RRB- cord-005646-xhx9pzhj 1036 15 days day NNS cord-005646-xhx9pzhj 1036 16 . . . cord-005646-xhx9pzhj 1037 1 Six six CD cord-005646-xhx9pzhj 1037 2 patients patient NNS cord-005646-xhx9pzhj 1037 3 needed need VBD cord-005646-xhx9pzhj 1037 4 peritoneal peritoneal NN cord-005646-xhx9pzhj 1037 5 or or CC cord-005646-xhx9pzhj 1037 6 hemodialysis hemodialysis NN cord-005646-xhx9pzhj 1037 7 for for IN cord-005646-xhx9pzhj 1037 8 31 31 CD cord-005646-xhx9pzhj 1037 9 days day NNS cord-005646-xhx9pzhj 1037 10 ( ( -LRB- cord-005646-xhx9pzhj 1037 11 median median NN cord-005646-xhx9pzhj 1037 12 ) ) -RRB- cord-005646-xhx9pzhj 1037 13 during during IN cord-005646-xhx9pzhj 1037 14 the the DT cord-005646-xhx9pzhj 1037 15 PO PO NNP cord-005646-xhx9pzhj 1037 16 period period NN cord-005646-xhx9pzhj 1037 17 . . . cord-005646-xhx9pzhj 1038 1 One one CD cord-005646-xhx9pzhj 1038 2 patient patient NN cord-005646-xhx9pzhj 1038 3 showed show VBD cord-005646-xhx9pzhj 1038 4 cerebral cerebral JJ cord-005646-xhx9pzhj 1038 5 infarction infarction NN cord-005646-xhx9pzhj 1038 6 due due IN cord-005646-xhx9pzhj 1038 7 to to IN cord-005646-xhx9pzhj 1038 8 thromboembolism thromboembolism NN cord-005646-xhx9pzhj 1038 9 in in IN cord-005646-xhx9pzhj 1038 10 the the DT cord-005646-xhx9pzhj 1038 11 territory territory NN cord-005646-xhx9pzhj 1038 12 of of IN cord-005646-xhx9pzhj 1038 13 the the DT cord-005646-xhx9pzhj 1038 14 right right JJ cord-005646-xhx9pzhj 1038 15 internal internal JJ cord-005646-xhx9pzhj 1038 16 carotid carotid NN cord-005646-xhx9pzhj 1038 17 artery artery NN cord-005646-xhx9pzhj 1038 18 immediately immediately RB cord-005646-xhx9pzhj 1038 19 after after IN cord-005646-xhx9pzhj 1038 20 the the DT cord-005646-xhx9pzhj 1038 21 operation operation NN cord-005646-xhx9pzhj 1038 22 . . . cord-005646-xhx9pzhj 1039 1 The the DT cord-005646-xhx9pzhj 1039 2 follow follow NN cord-005646-xhx9pzhj 1039 3 - - HYPH cord-005646-xhx9pzhj 1039 4 up up NN cord-005646-xhx9pzhj 1039 5 protocol protocol NN cord-005646-xhx9pzhj 1039 6 consisted consist VBN cord-005646-xhx9pzhj 1039 7 of of IN cord-005646-xhx9pzhj 1039 8 extensive extensive JJ cord-005646-xhx9pzhj 1039 9 investigations investigation NNS cord-005646-xhx9pzhj 1039 10 of of IN cord-005646-xhx9pzhj 1039 11 heart- heart- NNS cord-005646-xhx9pzhj 1039 12 , , , cord-005646-xhx9pzhj 1039 13 renalliver- renalliver- JJ cord-005646-xhx9pzhj 1039 14 , , , cord-005646-xhx9pzhj 1039 15 and and CC cord-005646-xhx9pzhj 1039 16 lung lung NN cord-005646-xhx9pzhj 1039 17 functions function NNS cord-005646-xhx9pzhj 1039 18 as as RB cord-005646-xhx9pzhj 1039 19 well well RB cord-005646-xhx9pzhj 1039 20 as as IN cord-005646-xhx9pzhj 1039 21 complete complete JJ cord-005646-xhx9pzhj 1039 22 neurological neurological JJ cord-005646-xhx9pzhj 1039 23 and and CC cord-005646-xhx9pzhj 1039 24 psychological psychological JJ cord-005646-xhx9pzhj 1039 25 examinations examination NNS cord-005646-xhx9pzhj 1039 26 . . . cord-005646-xhx9pzhj 1040 1 All all DT cord-005646-xhx9pzhj 1040 2 patients patient NNS cord-005646-xhx9pzhj 1040 3 had have VBD cord-005646-xhx9pzhj 1040 4 adequate adequate JJ cord-005646-xhx9pzhj 1040 5 cardiac cardiac JJ cord-005646-xhx9pzhj 1040 6 examination examination NN cord-005646-xhx9pzhj 1040 7 . . . cord-005646-xhx9pzhj 1041 1 Lung lung NN cord-005646-xhx9pzhj 1041 2 function function NN cord-005646-xhx9pzhj 1041 3 was be VBD cord-005646-xhx9pzhj 1041 4 normal normal JJ cord-005646-xhx9pzhj 1041 5 in in IN cord-005646-xhx9pzhj 1041 6 all all DT cord-005646-xhx9pzhj 1041 7 but but CC cord-005646-xhx9pzhj 1041 8 2 2 CD cord-005646-xhx9pzhj 1041 9 patients patient NNS cord-005646-xhx9pzhj 1041 10 who who WP cord-005646-xhx9pzhj 1041 11 had have VBD cord-005646-xhx9pzhj 1041 12 an an DT cord-005646-xhx9pzhj 1041 13 obstructive obstructive JJ cord-005646-xhx9pzhj 1041 14 syndrome syndrome NN cord-005646-xhx9pzhj 1041 15 . . . cord-005646-xhx9pzhj 1042 1 Only only RB cord-005646-xhx9pzhj 1042 2 1 1 CD cord-005646-xhx9pzhj 1042 3 patient patient NN cord-005646-xhx9pzhj 1042 4 showed show VBD cord-005646-xhx9pzhj 1042 5 an an DT cord-005646-xhx9pzhj 1042 6 isolated isolated JJ cord-005646-xhx9pzhj 1042 7 decreased decrease VBN cord-005646-xhx9pzhj 1042 8 creatinine creatinine NN cord-005646-xhx9pzhj 1042 9 clearance clearance NN cord-005646-xhx9pzhj 1042 10 . . . cord-005646-xhx9pzhj 1043 1 Abnormalities abnormality NNS cord-005646-xhx9pzhj 1043 2 of of IN cord-005646-xhx9pzhj 1043 3 the the DT cord-005646-xhx9pzhj 1043 4 liver liver NN cord-005646-xhx9pzhj 1043 5 ftmction ftmction NN cord-005646-xhx9pzhj 1043 6 tests test NNS cord-005646-xhx9pzhj 1043 7 were be VBD cord-005646-xhx9pzhj 1043 8 only only RB cord-005646-xhx9pzhj 1043 9 noticed notice VBN cord-005646-xhx9pzhj 1043 10 in in IN cord-005646-xhx9pzhj 1043 11 patients patient NNS cord-005646-xhx9pzhj 1043 12 after after IN cord-005646-xhx9pzhj 1043 13 Fontan Fontan NNP cord-005646-xhx9pzhj 1043 14 procedure procedure NN cord-005646-xhx9pzhj 1043 15 . . . cord-005646-xhx9pzhj 1044 1 Severe severe JJ cord-005646-xhx9pzhj 1044 2 neurological neurological JJ cord-005646-xhx9pzhj 1044 3 sequels sequel NNS cord-005646-xhx9pzhj 1044 4 such such JJ cord-005646-xhx9pzhj 1044 5 as as IN cord-005646-xhx9pzhj 1044 6 paraplegia paraplegia NNP cord-005646-xhx9pzhj 1044 7 ( ( -LRB- cord-005646-xhx9pzhj 1044 8 n n NN cord-005646-xhx9pzhj 1044 9 = = SYM cord-005646-xhx9pzhj 1044 10 1 1 CD cord-005646-xhx9pzhj 1044 11 ) ) -RRB- cord-005646-xhx9pzhj 1044 12 and and CC cord-005646-xhx9pzhj 1044 13 diplegia diplegia NNP cord-005646-xhx9pzhj 1044 14 ( ( -LRB- cord-005646-xhx9pzhj 1044 15 n n NNP cord-005646-xhx9pzhj 1044 16 - - : cord-005646-xhx9pzhj 1044 17 i i NNP cord-005646-xhx9pzhj 1044 18 ) ) -RRB- cord-005646-xhx9pzhj 1044 19 were be VBD cord-005646-xhx9pzhj 1044 20 observed observe VBN cord-005646-xhx9pzhj 1044 21 in in IN cord-005646-xhx9pzhj 1044 22 2 2 CD cord-005646-xhx9pzhj 1044 23 of of IN cord-005646-xhx9pzhj 1044 24 the the DT cord-005646-xhx9pzhj 1044 25 11 11 CD cord-005646-xhx9pzhj 1044 26 patients patient NNS cord-005646-xhx9pzhj 1044 27 . . . cord-005646-xhx9pzhj 1045 1 The the DT cord-005646-xhx9pzhj 1045 2 remaining remain VBG cord-005646-xhx9pzhj 1045 3 9 9 CD cord-005646-xhx9pzhj 1045 4 children child NNS cord-005646-xhx9pzhj 1045 5 presented present VBN cord-005646-xhx9pzhj 1045 6 with with IN cord-005646-xhx9pzhj 1045 7 a a DT cord-005646-xhx9pzhj 1045 8 delayed delay VBN cord-005646-xhx9pzhj 1045 9 graphomotorical graphomotorical JJ cord-005646-xhx9pzhj 1045 10 and and CC cord-005646-xhx9pzhj 1045 11 speech speech NN cord-005646-xhx9pzhj 1045 12 development development NN cord-005646-xhx9pzhj 1045 13 associated associate VBN cord-005646-xhx9pzhj 1045 14 with with IN cord-005646-xhx9pzhj 1045 15 normal normal JJ cord-005646-xhx9pzhj 1045 16 intelligence intelligence NN cord-005646-xhx9pzhj 1045 17 . . . cord-005646-xhx9pzhj 1046 1 -In -In . cord-005646-xhx9pzhj 1047 1 our -PRON- PRP$ cord-005646-xhx9pzhj 1047 2 series series NN cord-005646-xhx9pzhj 1047 3 the the DT cord-005646-xhx9pzhj 1047 4 most most RBS cord-005646-xhx9pzhj 1047 5 frequent frequent JJ cord-005646-xhx9pzhj 1047 6 and and CC cord-005646-xhx9pzhj 1047 7 severe severe JJ cord-005646-xhx9pzhj 1047 8 sequels sequel NNS cord-005646-xhx9pzhj 1047 9 after after IN cord-005646-xhx9pzhj 1047 10 postoperative postoperative JJ cord-005646-xhx9pzhj 1047 11 MOF MOF NNP cord-005646-xhx9pzhj 1047 12 were be VBD cord-005646-xhx9pzhj 1047 13 neurological neurological JJ cord-005646-xhx9pzhj 1047 14 . . . cord-005646-xhx9pzhj 1048 1 -Abnormal -Abnormal . cord-005646-xhx9pzhj 1049 1 liver liver NN cord-005646-xhx9pzhj 1049 2 fimction fimction NN cord-005646-xhx9pzhj 1049 3 tests test NNS cord-005646-xhx9pzhj 1049 4 are be VBP cord-005646-xhx9pzhj 1049 5 more more RBR cord-005646-xhx9pzhj 1049 6 likely likely JJ cord-005646-xhx9pzhj 1049 7 to to TO cord-005646-xhx9pzhj 1049 8 be be VB cord-005646-xhx9pzhj 1049 9 a a DT cord-005646-xhx9pzhj 1049 10 consequence consequence NN cord-005646-xhx9pzhj 1049 11 of of IN cord-005646-xhx9pzhj 1049 12 the the DT cord-005646-xhx9pzhj 1049 13 Fontan Fontan NNP cord-005646-xhx9pzhj 1049 14 hemodynamics hemodynamic NNS cord-005646-xhx9pzhj 1049 15 than than IN cord-005646-xhx9pzhj 1049 16 a a DT cord-005646-xhx9pzhj 1049 17 sequel sequel NN cord-005646-xhx9pzhj 1049 18 of of IN cord-005646-xhx9pzhj 1049 19 MOF MOF NNP cord-005646-xhx9pzhj 1049 20 . . . cord-005646-xhx9pzhj 1050 1 The the DT cord-005646-xhx9pzhj 1050 2 optimal optimal JJ cord-005646-xhx9pzhj 1050 3 dosing dosing NN cord-005646-xhx9pzhj 1050 4 schedule schedule NN cord-005646-xhx9pzhj 1050 5 of of IN cord-005646-xhx9pzhj 1050 6 surfactant surfactant NN cord-005646-xhx9pzhj 1050 7 therapy therapy NN cord-005646-xhx9pzhj 1050 8 for for IN cord-005646-xhx9pzhj 1050 9 the the DT cord-005646-xhx9pzhj 1050 10 treatment treatment NN cord-005646-xhx9pzhj 1050 11 of of IN cord-005646-xhx9pzhj 1050 12 neonatal neonatal JJ cord-005646-xhx9pzhj 1050 13 respiratory respiratory JJ cord-005646-xhx9pzhj 1050 14 distress distress NN cord-005646-xhx9pzhj 1050 15 syndrome syndrome NN cord-005646-xhx9pzhj 1050 16 ( ( -LRB- cord-005646-xhx9pzhj 1050 17 RDS RDS NNP cord-005646-xhx9pzhj 1050 18 ) ) -RRB- cord-005646-xhx9pzhj 1050 19 remains remain VBZ cord-005646-xhx9pzhj 1050 20 unclear unclear JJ cord-005646-xhx9pzhj 1050 21 . . . cord-005646-xhx9pzhj 1051 1 Goal goal NN cord-005646-xhx9pzhj 1051 2 : : : cord-005646-xhx9pzhj 1052 1 Surfaetant surfaetant JJ cord-005646-xhx9pzhj 1052 2 function function NN cord-005646-xhx9pzhj 1052 3 and and CC cord-005646-xhx9pzhj 1052 4 the the DT cord-005646-xhx9pzhj 1052 5 concentration concentration NN cord-005646-xhx9pzhj 1052 6 of of IN cord-005646-xhx9pzhj 1052 7 phospholipids phospholipid NNS cord-005646-xhx9pzhj 1052 8 ( ( -LRB- cord-005646-xhx9pzhj 1052 9 PL pl NN cord-005646-xhx9pzhj 1052 10 ) ) -RRB- cord-005646-xhx9pzhj 1052 11 in in IN cord-005646-xhx9pzhj 1052 12 tracheal tracheal JJ cord-005646-xhx9pzhj 1052 13 aspirates aspirate NNS cord-005646-xhx9pzhj 1052 14 are be VBP cord-005646-xhx9pzhj 1052 15 compared compare VBN cord-005646-xhx9pzhj 1052 16 in in IN cord-005646-xhx9pzhj 1052 17 a a DT cord-005646-xhx9pzhj 1052 18 prospective prospective JJ cord-005646-xhx9pzhj 1052 19 randomized randomized JJ cord-005646-xhx9pzhj 1052 20 trial trial NN cord-005646-xhx9pzhj 1052 21 involving involve VBG cord-005646-xhx9pzhj 1052 22 neonates neonate NNS cord-005646-xhx9pzhj 1052 23 with with IN cord-005646-xhx9pzhj 1052 24 RDS RDS NNP cord-005646-xhx9pzhj 1052 25 who who WP cord-005646-xhx9pzhj 1052 26 received receive VBD cord-005646-xhx9pzhj 1052 27 either either CC cord-005646-xhx9pzhj 1052 28 TWO two CD cord-005646-xhx9pzhj 1052 29 or or CC cord-005646-xhx9pzhj 1052 30 MORE MORE JJR cord-005646-xhx9pzhj 1052 31 ( ( -LRB- cord-005646-xhx9pzhj 1052 32 3 3 CD cord-005646-xhx9pzhj 1052 33 or or CC cord-005646-xhx9pzhj 1052 34 4 4 CD cord-005646-xhx9pzhj 1052 35 ) ) -RRB- cord-005646-xhx9pzhj 1052 36 doses dose NNS cord-005646-xhx9pzhj 1052 37 of of IN cord-005646-xhx9pzhj 1052 38 Survanta Survanta NNP cord-005646-xhx9pzhj 1052 39 . . . cord-005646-xhx9pzhj 1053 1 Methods method NNS cord-005646-xhx9pzhj 1053 2 ; ; , cord-005646-xhx9pzhj 1053 3 Ventilated ventilate VBN cord-005646-xhx9pzhj 1053 4 neonates neonate NNS cord-005646-xhx9pzhj 1053 5 < < XX cord-005646-xhx9pzhj 1053 6 35w 35w NNS cord-005646-xhx9pzhj 1053 7 with with IN cord-005646-xhx9pzhj 1053 8 RDS RDS NNP cord-005646-xhx9pzhj 1053 9 were be VBD cord-005646-xhx9pzhj 1053 10 treated treat VBN cord-005646-xhx9pzhj 1053 11 with with IN cord-005646-xhx9pzhj 1053 12 Survanta Survanta NNP cord-005646-xhx9pzhj 1053 13 1OO 1OO NNP cord-005646-xhx9pzhj 1053 14 mg mg NNP cord-005646-xhx9pzhj 1053 15 / / SYM cord-005646-xhx9pzhj 1053 16 kg kg NNP cord-005646-xhx9pzhj 1054 1 if if IN cord-005646-xhx9pzhj 1054 2 FiO FiO NNP cord-005646-xhx9pzhj 1054 3 2 2 CD cord-005646-xhx9pzhj 1054 4 > > XX cord-005646-xhx9pzhj 1055 1 _ _ NN cord-005646-xhx9pzhj 1055 2 40 40 CD cord-005646-xhx9pzhj 1055 3 % % NN cord-005646-xhx9pzhj 1055 4 or or CC cord-005646-xhx9pzhj 1055 5 mean mean VB cord-005646-xhx9pzhj 1055 6 airway airway NN cord-005646-xhx9pzhj 1055 7 pressure pressure NN cord-005646-xhx9pzhj 1055 8 _ _ NNP cord-005646-xhx9pzhj 1055 9 > > XX cord-005646-xhx9pzhj 1055 10 7,5 7,5 CD cord-005646-xhx9pzhj 1055 11 cm cm NN cord-005646-xhx9pzhj 1055 12 HzO hzo NN cord-005646-xhx9pzhj 1055 13 , , , cord-005646-xhx9pzhj 1055 14 After after IN cord-005646-xhx9pzhj 1055 15 6h 6h NNP cord-005646-xhx9pzhj 1055 16 a a DT cord-005646-xhx9pzhj 1055 17 2nd 2nd JJ cord-005646-xhx9pzhj 1055 18 dose dose NN cord-005646-xhx9pzhj 1055 19 was be VBD cord-005646-xhx9pzhj 1055 20 given give VBN cord-005646-xhx9pzhj 1055 21 ( ( -LRB- cord-005646-xhx9pzhj 1055 22 same same JJ cord-005646-xhx9pzhj 1055 23 criteria criterion NNS cord-005646-xhx9pzhj 1055 24 ) ) -RRB- cord-005646-xhx9pzhj 1055 25 , , , cord-005646-xhx9pzhj 1055 26 If if IN cord-005646-xhx9pzhj 1055 27 the the DT cord-005646-xhx9pzhj 1055 28 support support NN cord-005646-xhx9pzhj 1055 29 still still RB cord-005646-xhx9pzhj 1055 30 exceeded exceed VBD cord-005646-xhx9pzhj 1055 31 the the DT cord-005646-xhx9pzhj 1055 32 criteria criterion NNS cord-005646-xhx9pzhj 1055 33 12h 12h -RRB- cord-005646-xhx9pzhj 1055 34 after after IN cord-005646-xhx9pzhj 1055 35 the the DT cord-005646-xhx9pzhj 1055 36 2nd 2nd JJ cord-005646-xhx9pzhj 1055 37 dose dose NN cord-005646-xhx9pzhj 1055 38 , , , cord-005646-xhx9pzhj 1055 39 the the DT cord-005646-xhx9pzhj 1055 40 patient patient NN cord-005646-xhx9pzhj 1055 41 was be VBD cord-005646-xhx9pzhj 1055 42 randomized randomized JJ cord-005646-xhx9pzhj 1055 43 to to IN cord-005646-xhx9pzhj 1055 44 no no DT cord-005646-xhx9pzhj 1055 45 extra extra JJ cord-005646-xhx9pzhj 1055 46 dose dose NN cord-005646-xhx9pzhj 1055 47 ( ( -LRB- cord-005646-xhx9pzhj 1055 48 TWO two CD cord-005646-xhx9pzhj 1055 49 } } -RRB- cord-005646-xhx9pzhj 1055 50 , , , cord-005646-xhx9pzhj 1055 51 or or CC cord-005646-xhx9pzhj 1055 52 to to IN cord-005646-xhx9pzhj 1055 53 an an DT cord-005646-xhx9pzhj 1055 54 extra extra JJ cord-005646-xhx9pzhj 1055 55 dose dose NN cord-005646-xhx9pzhj 1055 56 of of IN cord-005646-xhx9pzhj 1055 57 Survanta Survanta NNP cord-005646-xhx9pzhj 1055 58 ( ( -LRB- cord-005646-xhx9pzhj 1055 59 MOREl MOREl NNP cord-005646-xhx9pzhj 1055 60 ( ( -LRB- cord-005646-xhx9pzhj 1055 61 and and CC cord-005646-xhx9pzhj 1055 62 a a DT cord-005646-xhx9pzhj 1055 63 4th 4th JJ cord-005646-xhx9pzhj 1055 64 dose dose NN cord-005646-xhx9pzhj 1055 65 12h 12h -RRB- cord-005646-xhx9pzhj 1055 66 later later RB cord-005646-xhx9pzhj 1055 67 ; ; , cord-005646-xhx9pzhj 1055 68 same same JJ cord-005646-xhx9pzhj 1055 69 criteria criterion NNS cord-005646-xhx9pzhj 1055 70 ) ) -RRB- cord-005646-xhx9pzhj 1055 71 , , , cord-005646-xhx9pzhj 1055 72 PL PL NNP cord-005646-xhx9pzhj 1055 73 was be VBD cord-005646-xhx9pzhj 1055 74 measured measure VBN cord-005646-xhx9pzhj 1055 75 in in IN cord-005646-xhx9pzhj 1055 76 tracheal tracheal JJ cord-005646-xhx9pzhj 1055 77 aspirates aspirate NNS cord-005646-xhx9pzhj 1055 78 and and CC cord-005646-xhx9pzhj 1055 79 corrected correct VBN cord-005646-xhx9pzhj 1055 80 for for IN cord-005646-xhx9pzhj 1055 81 dilution dilution NN cord-005646-xhx9pzhj 1055 82 with with IN cord-005646-xhx9pzhj 1055 83 the the DT cord-005646-xhx9pzhj 1055 84 urea urea NN cord-005646-xhx9pzhj 1055 85 method method NN cord-005646-xhx9pzhj 1055 86 . . . cord-005646-xhx9pzhj 1056 1 " " `` cord-005646-xhx9pzhj 1056 2 Active active JJ cord-005646-xhx9pzhj 1056 3 " " '' cord-005646-xhx9pzhj 1056 4 large large JJ cord-005646-xhx9pzhj 1056 5 aggregates aggregate NNS cord-005646-xhx9pzhj 1056 6 and and CC cord-005646-xhx9pzhj 1056 7 " " `` cord-005646-xhx9pzhj 1056 8 non non JJ cord-005646-xhx9pzhj 1056 9 - - JJ cord-005646-xhx9pzhj 1056 10 active active JJ cord-005646-xhx9pzhj 1056 11 " " '' cord-005646-xhx9pzhj 1056 12 small small JJ cord-005646-xhx9pzhj 1056 13 aggregates aggregate NNS cord-005646-xhx9pzhj 1056 14 of of IN cord-005646-xhx9pzhj 1056 15 surfactant surfactant NN cord-005646-xhx9pzhj 1056 16 were be VBD cord-005646-xhx9pzhj 1056 17 separated separate VBN cord-005646-xhx9pzhj 1056 18 by by IN cord-005646-xhx9pzhj 1056 19 centrifugation centrifugation NN cord-005646-xhx9pzhj 1056 20 and and CC cord-005646-xhx9pzhj 1056 21 quantified quantify VBN cord-005646-xhx9pzhj 1056 22 . . . cord-005646-xhx9pzhj 1057 1 Surface surface NN cord-005646-xhx9pzhj 1057 2 tension tension NN cord-005646-xhx9pzhj 1057 3 of of IN cord-005646-xhx9pzhj 1057 4 the the DT cord-005646-xhx9pzhj 1057 5 large large JJ cord-005646-xhx9pzhj 1057 6 aggregate aggregate JJ cord-005646-xhx9pzhj 1057 7 fraction fraction NN cord-005646-xhx9pzhj 1057 8 was be VBD cord-005646-xhx9pzhj 1057 9 measured measure VBN cord-005646-xhx9pzhj 1057 10 by by IN cord-005646-xhx9pzhj 1057 11 pulsating pulsate VBG cord-005646-xhx9pzhj 1057 12 bubble bubble NN cord-005646-xhx9pzhj 1057 13 surfactometer surfactometer NN cord-005646-xhx9pzhj 1057 14 , , , cord-005646-xhx9pzhj 1057 15 Results result NNS cord-005646-xhx9pzhj 1057 16 : : : cord-005646-xhx9pzhj 1058 1 13 13 CD cord-005646-xhx9pzhj 1058 2 neonates neonate NNS cord-005646-xhx9pzhj 1058 3 were be VBD cord-005646-xhx9pzhj 1058 4 randomized randomize VBN cord-005646-xhx9pzhj 1058 5 , , , cord-005646-xhx9pzhj 1058 6 6x 6x CD cord-005646-xhx9pzhj 1058 7 TWO two CD cord-005646-xhx9pzhj 1058 8 and and CC cord-005646-xhx9pzhj 1058 9 7x 7x CD cord-005646-xhx9pzhj 1058 10 MORE MORE JJR cord-005646-xhx9pzhj 1059 1 ( ( -LRB- cord-005646-xhx9pzhj 1059 2 5x3 5x3 CD cord-005646-xhx9pzhj 1059 3 and and CC cord-005646-xhx9pzhj 1059 4 2x4 2x4 CD cord-005646-xhx9pzhj 1059 5 doses dose NNS cord-005646-xhx9pzhj 1059 6 ) ) -RRB- cord-005646-xhx9pzhj 1059 7 , , , cord-005646-xhx9pzhj 1059 8 Gestational Gestational NNP cord-005646-xhx9pzhj 1059 9 age age NN cord-005646-xhx9pzhj 1059 10 was be VBD cord-005646-xhx9pzhj 1059 11 31,7±2,4w 31,7±2,4w CD cord-005646-xhx9pzhj 1059 12 and and CC cord-005646-xhx9pzhj 1059 13 birth birth NN cord-005646-xhx9pzhj 1059 14 weight weight NN cord-005646-xhx9pzhj 1059 15 1582±568 1582±568 CD cord-005646-xhx9pzhj 1059 16 g g NN cord-005646-xhx9pzhj 1059 17 . . . cord-005646-xhx9pzhj 1060 1 Most Most JJS cord-005646-xhx9pzhj 1060 2 patients patient NNS cord-005646-xhx9pzhj 1060 3 had have VBD cord-005646-xhx9pzhj 1060 4 severe severe JJ cord-005646-xhx9pzhj 1060 5 RDS RDS NNP cord-005646-xhx9pzhj 1060 6 with with IN cord-005646-xhx9pzhj 1060 7 initial initial JJ cord-005646-xhx9pzhj 1060 8 ventilation ventilation NN cord-005646-xhx9pzhj 1060 9 : : : cord-005646-xhx9pzhj 1060 10 rate rate NN cord-005646-xhx9pzhj 1060 11 63.1_+11,1 63.1_+11,1 CD cord-005646-xhx9pzhj 1060 12 , , , cord-005646-xhx9pzhj 1060 13 peak peak JJ cord-005646-xhx9pzhj 1060 14 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1060 15 pressure pressure NN cord-005646-xhx9pzhj 1060 16 ( ( -LRB- cord-005646-xhx9pzhj 1060 17 PIP PIP NNP cord-005646-xhx9pzhj 1060 18 ) ) -RRB- cord-005646-xhx9pzhj 1060 19 24,3-+6.4 24,3-+6.4 CD cord-005646-xhx9pzhj 1060 20 cm cm NNS cord-005646-xhx9pzhj 1060 21 HzO hzo NN cord-005646-xhx9pzhj 1060 22 , , , cord-005646-xhx9pzhj 1060 23 FiO FiO NNP cord-005646-xhx9pzhj 1060 24 2 2 CD cord-005646-xhx9pzhj 1060 25 75.3±21.0 75.3±21.0 CD cord-005646-xhx9pzhj 1060 26 % % NN cord-005646-xhx9pzhj 1060 27 . . . cord-005646-xhx9pzhj 1061 1 At at IN cord-005646-xhx9pzhj 1061 2 randomization randomization NN cord-005646-xhx9pzhj 1061 3 : : : cord-005646-xhx9pzhj 1061 4 rate rate NN cord-005646-xhx9pzhj 1061 5 63.5±6.9 63.5±6.9 CD cord-005646-xhx9pzhj 1061 6 , , , cord-005646-xhx9pzhj 1061 7 PIP PIP NNP cord-005646-xhx9pzhj 1061 8 20.3-+2.5 20.3-+2.5 NNP cord-005646-xhx9pzhj 1061 9 cm cm NNP cord-005646-xhx9pzhj 1061 10 HzO HzO NNP cord-005646-xhx9pzhj 1061 11 , , , cord-005646-xhx9pzhj 1061 12 FiO FiO NNP cord-005646-xhx9pzhj 1061 13 2 2 CD cord-005646-xhx9pzhj 1061 14 29.5±15.7 29.5±15.7 CD cord-005646-xhx9pzhj 1061 15 % % NN cord-005646-xhx9pzhj 1061 16 , , , cord-005646-xhx9pzhj 1061 17 and and CC cord-005646-xhx9pzhj 1061 18 24 24 CD cord-005646-xhx9pzhj 1061 19 h h NN cord-005646-xhx9pzhj 1061 20 after after IN cord-005646-xhx9pzhj 1061 21 randomization randomization NN cord-005646-xhx9pzhj 1061 22 : : : cord-005646-xhx9pzhj 1061 23 rate rate NN cord-005646-xhx9pzhj 1061 24 45.9±17.1 45.9±17.1 CD cord-005646-xhx9pzhj 1061 25 , , , cord-005646-xhx9pzhj 1061 26 PIP PIP NNP cord-005646-xhx9pzhj 1061 27 18.7_+2.2 18.7_+2.2 CD cord-005646-xhx9pzhj 1061 28 cm cm NNP cord-005646-xhx9pzhj 1061 29 HzO hzo NN cord-005646-xhx9pzhj 1061 30 , , , cord-005646-xhx9pzhj 1062 1 FiO FiO NNP cord-005646-xhx9pzhj 1062 2 2 2 CD cord-005646-xhx9pzhj 1062 3 26.8±6.6 26.8±6.6 CD cord-005646-xhx9pzhj 1062 4 % % NN cord-005646-xhx9pzhj 1062 5 , , , cord-005646-xhx9pzhj 1062 6 without without IN cord-005646-xhx9pzhj 1062 7 signif signif NNS cord-005646-xhx9pzhj 1062 8 , , , cord-005646-xhx9pzhj 1062 9 differences difference NNS cord-005646-xhx9pzhj 1062 10 between between IN cord-005646-xhx9pzhj 1062 11 the the DT cord-005646-xhx9pzhj 1062 12 groups group NNS cord-005646-xhx9pzhj 1062 13 . . . cord-005646-xhx9pzhj 1063 1 There there EX cord-005646-xhx9pzhj 1063 2 was be VBD cord-005646-xhx9pzhj 1063 3 1 1 CD cord-005646-xhx9pzhj 1063 4 relapse relapse NN cord-005646-xhx9pzhj 1063 5 ( ( -LRB- cord-005646-xhx9pzhj 1063 6 again again RB cord-005646-xhx9pzhj 1063 7 FIO2_>60 fio2_>60 NN cord-005646-xhx9pzhj 1063 8 % % NN cord-005646-xhx9pzhj 1063 9 within within IN cord-005646-xhx9pzhj 1063 10 72h 72h NNP cord-005646-xhx9pzhj 1063 11 ) ) -RRB- cord-005646-xhx9pzhj 1063 12 in in IN cord-005646-xhx9pzhj 1063 13 group group NN cord-005646-xhx9pzhj 1063 14 TWO two CD cord-005646-xhx9pzhj 1063 15 and and CC cord-005646-xhx9pzhj 1063 16 t t VBD cord-005646-xhx9pzhj 1063 17 BPD BPD NNP cord-005646-xhx9pzhj 1063 18 in in IN cord-005646-xhx9pzhj 1063 19 group group NN cord-005646-xhx9pzhj 1063 20 MORE MORE JJR cord-005646-xhx9pzhj 1063 21 . . . cord-005646-xhx9pzhj 1064 1 In in IN cord-005646-xhx9pzhj 1064 2 total total NN cord-005646-xhx9pzhj 1064 3 , , , cord-005646-xhx9pzhj 1064 4 112 112 CD cord-005646-xhx9pzhj 1064 5 tracheal tracheal NN cord-005646-xhx9pzhj 1064 6 aspirates aspirate NNS cord-005646-xhx9pzhj 1064 7 were be VBD cord-005646-xhx9pzhj 1064 8 analyzed analyze VBN cord-005646-xhx9pzhj 1064 9 . . . cord-005646-xhx9pzhj 1065 1 PL PL NNP cord-005646-xhx9pzhj 1065 2 was be VBD cord-005646-xhx9pzhj 1065 3 not not RB cord-005646-xhx9pzhj 1065 4 signif signif NNS cord-005646-xhx9pzhj 1065 5 , , , cord-005646-xhx9pzhj 1065 6 different different JJ cord-005646-xhx9pzhj 1065 7 before before IN cord-005646-xhx9pzhj 1065 8 randomization randomization NN cord-005646-xhx9pzhj 1065 9 ( ( -LRB- cord-005646-xhx9pzhj 1065 10 TWO two CD cord-005646-xhx9pzhj 1065 11 27.5 27.5 CD cord-005646-xhx9pzhj 1065 12 ± ± CD cord-005646-xhx9pzhj 1065 13 15.7 15.7 CD cord-005646-xhx9pzhj 1065 14 vs vs IN cord-005646-xhx9pzhj 1065 15 MORE MORE JJR cord-005646-xhx9pzhj 1065 16 24.5 24.5 CD cord-005646-xhx9pzhj 1065 17 ± ± CD cord-005646-xhx9pzhj 1065 18 11.4 11.4 CD cord-005646-xhx9pzhj 1065 19 /Jmol /jmol NN cord-005646-xhx9pzhj 1065 20 / / SYM cord-005646-xhx9pzhj 1065 21 ml ml NN cord-005646-xhx9pzhj 1065 22 ) ) -RRB- cord-005646-xhx9pzhj 1065 23 , , , cord-005646-xhx9pzhj 1065 24 but but CC cord-005646-xhx9pzhj 1065 25 neither neither CC cord-005646-xhx9pzhj 1065 26 after after IN cord-005646-xhx9pzhj 1065 27 randomization randomization NN cord-005646-xhx9pzhj 1065 28 ( ( -LRB- cord-005646-xhx9pzhj 1065 29 TWO two CD cord-005646-xhx9pzhj 1065 30 21.2-+ 21.2-+ CD cord-005646-xhx9pzhj 1065 31 11.0 11.0 CD cord-005646-xhx9pzhj 1065 32 vs vs IN cord-005646-xhx9pzhj 1065 33 MORE MORE JJR cord-005646-xhx9pzhj 1065 34 19.3±7,O 19.3±7,o CD cord-005646-xhx9pzhj 1066 1 /~mol /~mol NNP cord-005646-xhx9pzhj 1066 2 / / SYM cord-005646-xhx9pzhj 1066 3 ml ml NN cord-005646-xhx9pzhj 1066 4 ) ) -RRB- cord-005646-xhx9pzhj 1066 5 . . . cord-005646-xhx9pzhj 1067 1 There there EX cord-005646-xhx9pzhj 1067 2 was be VBD cord-005646-xhx9pzhj 1067 3 no no DT cord-005646-xhx9pzhj 1067 4 difference difference NN cord-005646-xhx9pzhj 1067 5 in in IN cord-005646-xhx9pzhj 1067 6 the the DT cord-005646-xhx9pzhj 1067 7 % % NN cord-005646-xhx9pzhj 1067 8 small small JJ cord-005646-xhx9pzhj 1067 9 aggregates aggregate NNS cord-005646-xhx9pzhj 1067 10 ( ( -LRB- cord-005646-xhx9pzhj 1067 11 TWO two CD cord-005646-xhx9pzhj 1067 12 4.2±1.9 4.2±1.9 CD cord-005646-xhx9pzhj 1067 13 vs vs IN cord-005646-xhx9pzhj 1067 14 MORE MORE JJR cord-005646-xhx9pzhj 1067 15 6.9±5.5 6.9±5.5 CD cord-005646-xhx9pzhj 1067 16 % % NN cord-005646-xhx9pzhj 1067 17 ) ) -RRB- cord-005646-xhx9pzhj 1067 18 , , , cord-005646-xhx9pzhj 1067 19 The the DT cord-005646-xhx9pzhj 1067 20 surface surface NN cord-005646-xhx9pzhj 1067 21 tensions tension NNS cord-005646-xhx9pzhj 1067 22 ( ( -LRB- cord-005646-xhx9pzhj 1067 23 raN ran NN cord-005646-xhx9pzhj 1067 24 / / SYM cord-005646-xhx9pzhj 1067 25 m m NN cord-005646-xhx9pzhj 1067 26 ) ) -RRB- cord-005646-xhx9pzhj 1067 27 were be VBD cord-005646-xhx9pzhj 1067 28 not not RB cord-005646-xhx9pzhj 1067 29 signif signif JJ cord-005646-xhx9pzhj 1067 30 , , , cord-005646-xhx9pzhj 1067 31 different different JJ cord-005646-xhx9pzhj 1067 32 ( ( -LRB- cord-005646-xhx9pzhj 1067 33 each each DT cord-005646-xhx9pzhj 1067 34 time time NN cord-005646-xhx9pzhj 1067 35 TWO two CD cord-005646-xhx9pzhj 1067 36 vs vs IN cord-005646-xhx9pzhj 1067 37 MORE more RBR cord-005646-xhx9pzhj 1067 38 ) ) -RRB- cord-005646-xhx9pzhj 1067 39 : : : cord-005646-xhx9pzhj 1067 40 before before IN cord-005646-xhx9pzhj 1067 41 randomization randomization NN cord-005646-xhx9pzhj 1067 42 10.0±2,3 10.0±2,3 CD cord-005646-xhx9pzhj 1067 43 vs vs IN cord-005646-xhx9pzhj 1067 44 14.2-+7.2 14.2-+7.2 CD cord-005646-xhx9pzhj 1067 45 , , , cord-005646-xhx9pzhj 1067 46 in in IN cord-005646-xhx9pzhj 1067 47 the the DT cord-005646-xhx9pzhj 1067 48 24h 24h NNS cord-005646-xhx9pzhj 1067 49 after after IN cord-005646-xhx9pzhj 1067 50 randomization randomization NN cord-005646-xhx9pzhj 1067 51 12.6±5.0 12.6±5.0 CD cord-005646-xhx9pzhj 1067 52 vs vs IN cord-005646-xhx9pzhj 1067 53 11.2-+3,8 11.2-+3,8 CD cord-005646-xhx9pzhj 1067 54 , , , cord-005646-xhx9pzhj 1067 55 or or CC cord-005646-xhx9pzhj 1067 56 24 24 CD cord-005646-xhx9pzhj 1067 57 - - SYM cord-005646-xhx9pzhj 1067 58 48h 48h NNS cord-005646-xhx9pzhj 1067 59 after after IN cord-005646-xhx9pzhj 1067 60 randomization randomization NN cord-005646-xhx9pzhj 1067 61 17.0-+5.5 17.0-+5.5 CD cord-005646-xhx9pzhj 1067 62 vs vs IN cord-005646-xhx9pzhj 1067 63 12.8±9.8 12.8±9.8 CD cord-005646-xhx9pzhj 1067 64 , , , cord-005646-xhx9pzhj 1067 65 or or CC cord-005646-xhx9pzhj 1067 66 48 48 CD cord-005646-xhx9pzhj 1067 67 - - HYPH cord-005646-xhx9pzhj 1067 68 72h 72h NNS cord-005646-xhx9pzhj 1067 69 after after IN cord-005646-xhx9pzhj 1067 70 randomization randomization NN cord-005646-xhx9pzhj 1067 71 15.7_+0.4 15.7_+0.4 CD cord-005646-xhx9pzhj 1067 72 vs vs IN cord-005646-xhx9pzhj 1067 73 13.7-+5.6 13.7-+5.6 CD cord-005646-xhx9pzhj 1067 74 . . . cord-005646-xhx9pzhj 1068 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1068 2 : : : cord-005646-xhx9pzhj 1068 3 Neonates Neonates NNP cord-005646-xhx9pzhj 1068 4 who who WP cord-005646-xhx9pzhj 1068 5 received receive VBD cord-005646-xhx9pzhj 1068 6 more more JJR cord-005646-xhx9pzhj 1068 7 than than IN cord-005646-xhx9pzhj 1068 8 two two CD cord-005646-xhx9pzhj 1068 9 doses dose NNS cord-005646-xhx9pzhj 1068 10 of of IN cord-005646-xhx9pzhj 1068 11 Survanta Survanta NNP cord-005646-xhx9pzhj 1068 12 did do VBD cord-005646-xhx9pzhj 1068 13 not not RB cord-005646-xhx9pzhj 1068 14 have have VB cord-005646-xhx9pzhj 1068 15 higher high JJR cord-005646-xhx9pzhj 1068 16 PL pl NN cord-005646-xhx9pzhj 1068 17 , , , cord-005646-xhx9pzhj 1068 18 nor nor CC cord-005646-xhx9pzhj 1068 19 a a DT cord-005646-xhx9pzhj 1068 20 better well JJR cord-005646-xhx9pzhj 1068 21 surfactant surfactant NN cord-005646-xhx9pzhj 1068 22 function function NN cord-005646-xhx9pzhj 1068 23 than than IN cord-005646-xhx9pzhj 1068 24 neonates neonate NNS cord-005646-xhx9pzhj 1068 25 who who WP cord-005646-xhx9pzhj 1068 26 received receive VBD cord-005646-xhx9pzhj 1068 27 only only RB cord-005646-xhx9pzhj 1068 28 two two CD cord-005646-xhx9pzhj 1068 29 doses dose NNS cord-005646-xhx9pzhj 1068 30 of of IN cord-005646-xhx9pzhj 1068 31 Survanta Survanta NNP cord-005646-xhx9pzhj 1068 32 . . . cord-005646-xhx9pzhj 1069 1 Continuation continuation NN cord-005646-xhx9pzhj 1069 2 of of IN cord-005646-xhx9pzhj 1069 3 the the DT cord-005646-xhx9pzhj 1069 4 trial trial NN cord-005646-xhx9pzhj 1069 5 is be VBZ cord-005646-xhx9pzhj 1069 6 necessary necessary JJ cord-005646-xhx9pzhj 1069 7 to to TO cord-005646-xhx9pzhj 1069 8 evaluate evaluate VB cord-005646-xhx9pzhj 1069 9 clinical clinical JJ cord-005646-xhx9pzhj 1069 10 outcome outcome NN cord-005646-xhx9pzhj 1069 11 . . . cord-005646-xhx9pzhj 1070 1 MAY MAY MD cord-005646-xhx9pzhj 1070 2 NOT not RB cord-005646-xhx9pzhj 1070 3 INDICATE indicate VB cord-005646-xhx9pzhj 1070 4 NEED need VB cord-005646-xhx9pzhj 1070 5 FOR for IN cord-005646-xhx9pzhj 1070 6 TREATMENT treatment NN cord-005646-xhx9pzhj 1071 1 P.C. P.C. NNP cord-005646-xhx9pzhj 1071 2 Clemens Clemens NNP cord-005646-xhx9pzhj 1071 3 S.J. S.J. NNP cord-005646-xhx9pzhj 1071 4 Neumann Neumann NNP cord-005646-xhx9pzhj 1071 5 University University NNP cord-005646-xhx9pzhj 1071 6 of of IN cord-005646-xhx9pzhj 1071 7 Hamburg Hamburg NNP cord-005646-xhx9pzhj 1071 8 , , , cord-005646-xhx9pzhj 1071 9 Department Department NNP cord-005646-xhx9pzhj 1071 10 of of IN cord-005646-xhx9pzhj 1071 11 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 1071 12 , , , cord-005646-xhx9pzhj 1071 13 Klinikum Klinikum NNP cord-005646-xhx9pzhj 1071 14 Schwerin Schwerin NNP cord-005646-xhx9pzhj 1071 15 , , , cord-005646-xhx9pzhj 1071 16 Wismarsche Wismarsche NNP cord-005646-xhx9pzhj 1071 17 Str Str NNP cord-005646-xhx9pzhj 1071 18 .. .. NFP cord-005646-xhx9pzhj 1071 19 397 397 CD cord-005646-xhx9pzhj 1071 20 , , , cord-005646-xhx9pzhj 1071 21 D-19049 d-19049 JJ cord-005646-xhx9pzhj 1071 22 Schwerin Schwerin NNP cord-005646-xhx9pzhj 1071 23 . . . cord-005646-xhx9pzhj 1072 1 Aim Aim NNP cord-005646-xhx9pzhj 1072 2 of of IN cord-005646-xhx9pzhj 1072 3 the the DT cord-005646-xhx9pzhj 1072 4 study study NN cord-005646-xhx9pzhj 1072 5 : : : cord-005646-xhx9pzhj 1072 6 The the DT cord-005646-xhx9pzhj 1072 7 finding finding NN cord-005646-xhx9pzhj 1072 8 of of IN cord-005646-xhx9pzhj 1072 9 elevated elevated JJ cord-005646-xhx9pzhj 1072 10 TSH tsh NN cord-005646-xhx9pzhj 1072 11 and and CC cord-005646-xhx9pzhj 1072 12 decreased decrease VBD cord-005646-xhx9pzhj 1072 13 T4 T4 NNP cord-005646-xhx9pzhj 1072 14 in in IN cord-005646-xhx9pzhj 1072 15 the the DT cord-005646-xhx9pzhj 1072 16 newborn newborn NN cord-005646-xhx9pzhj 1072 17 usually usually RB cord-005646-xhx9pzhj 1072 18 is be VBZ cord-005646-xhx9pzhj 1072 19 classified classify VBN cord-005646-xhx9pzhj 1072 20 as as IN cord-005646-xhx9pzhj 1072 21 " " `` cord-005646-xhx9pzhj 1072 22 transient transient JJ cord-005646-xhx9pzhj 1072 23 hypothyroidism hypothyroidism NN cord-005646-xhx9pzhj 1072 24 " " '' cord-005646-xhx9pzhj 1072 25 , , , cord-005646-xhx9pzhj 1072 26 thus thus RB cord-005646-xhx9pzhj 1072 27 the the DT cord-005646-xhx9pzhj 1072 28 elevation elevation NN cord-005646-xhx9pzhj 1072 29 of of IN cord-005646-xhx9pzhj 1072 30 TSH TSH NNP cord-005646-xhx9pzhj 1072 31 is be VBZ cord-005646-xhx9pzhj 1072 32 classified classify VBN cord-005646-xhx9pzhj 1072 33 as as IN cord-005646-xhx9pzhj 1072 34 consequence consequence NN cord-005646-xhx9pzhj 1072 35 of of IN cord-005646-xhx9pzhj 1072 36 the the DT cord-005646-xhx9pzhj 1072 37 lowered lower VBN cord-005646-xhx9pzhj 1072 38 T4 T4 NNP cord-005646-xhx9pzhj 1072 39 . . . cord-005646-xhx9pzhj 1073 1 But but CC cord-005646-xhx9pzhj 1073 2 on on IN cord-005646-xhx9pzhj 1073 3 the the DT cord-005646-xhx9pzhj 1073 4 other other JJ cord-005646-xhx9pzhj 1073 5 hand hand NN cord-005646-xhx9pzhj 1073 6 several several JJ cord-005646-xhx9pzhj 1073 7 data data NN cord-005646-xhx9pzhj 1073 8 sets set NNS cord-005646-xhx9pzhj 1073 9 show show VBP cord-005646-xhx9pzhj 1073 10 that that IN cord-005646-xhx9pzhj 1073 11 TSH TSH NNP cord-005646-xhx9pzhj 1073 12 elevation elevation NN cord-005646-xhx9pzhj 1073 13 as as RB cord-005646-xhx9pzhj 1073 14 well well RB cord-005646-xhx9pzhj 1073 15 as as IN cord-005646-xhx9pzhj 1073 16 low low JJ cord-005646-xhx9pzhj 1073 17 T4 T4 NNP cord-005646-xhx9pzhj 1073 18 , , , cord-005646-xhx9pzhj 1073 19 one one CD cord-005646-xhx9pzhj 1073 20 independently independently RB cord-005646-xhx9pzhj 1073 21 of of IN cord-005646-xhx9pzhj 1073 22 the the DT cord-005646-xhx9pzhj 1073 23 other other JJ cord-005646-xhx9pzhj 1073 24 one one NN cord-005646-xhx9pzhj 1073 25 , , , cord-005646-xhx9pzhj 1073 26 are be VBP cord-005646-xhx9pzhj 1073 27 associated associate VBN cord-005646-xhx9pzhj 1073 28 with with IN cord-005646-xhx9pzhj 1073 29 different different JJ cord-005646-xhx9pzhj 1073 30 kinds kind NNS cord-005646-xhx9pzhj 1073 31 of of IN cord-005646-xhx9pzhj 1073 32 perinatal perinatal JJ cord-005646-xhx9pzhj 1073 33 stress stress NN cord-005646-xhx9pzhj 1073 34 . . . cord-005646-xhx9pzhj 1074 1 Each each DT cord-005646-xhx9pzhj 1074 2 of of IN cord-005646-xhx9pzhj 1074 3 these these DT cord-005646-xhx9pzhj 1074 4 laboratory laboratory NN cord-005646-xhx9pzhj 1074 5 deviations deviation NNS cord-005646-xhx9pzhj 1074 6 , , , cord-005646-xhx9pzhj 1074 7 if if IN cord-005646-xhx9pzhj 1074 8 not not RB cord-005646-xhx9pzhj 1074 9 associated associate VBN cord-005646-xhx9pzhj 1074 10 with with IN cord-005646-xhx9pzhj 1074 11 the the DT cord-005646-xhx9pzhj 1074 12 other other JJ cord-005646-xhx9pzhj 1074 13 value value NN cord-005646-xhx9pzhj 1074 14 being be VBG cord-005646-xhx9pzhj 1074 15 abnormal abnormal JJ cord-005646-xhx9pzhj 1074 16 too too RB cord-005646-xhx9pzhj 1074 17 , , , cord-005646-xhx9pzhj 1074 18 is be VBZ cord-005646-xhx9pzhj 1074 19 generally generally RB cord-005646-xhx9pzhj 1074 20 accepted accept VBN cord-005646-xhx9pzhj 1074 21 not not RB cord-005646-xhx9pzhj 1074 22 to to TO cord-005646-xhx9pzhj 1074 23 be be VB cord-005646-xhx9pzhj 1074 24 an an DT cord-005646-xhx9pzhj 1074 25 indication indication NN cord-005646-xhx9pzhj 1074 26 for for IN cord-005646-xhx9pzhj 1074 27 treatment treatment NN cord-005646-xhx9pzhj 1074 28 . . . cord-005646-xhx9pzhj 1075 1 From from IN cord-005646-xhx9pzhj 1075 2 this this DT cord-005646-xhx9pzhj 1075 3 we -PRON- PRP cord-005646-xhx9pzhj 1075 4 conclude conclude VBP cord-005646-xhx9pzhj 1075 5 , , , cord-005646-xhx9pzhj 1075 6 that that IN cord-005646-xhx9pzhj 1075 7 more more JJR cord-005646-xhx9pzhj 1075 8 pefinatal pefinatal JJ cord-005646-xhx9pzhj 1075 9 stress stress NN cord-005646-xhx9pzhj 1075 10 , , , cord-005646-xhx9pzhj 1075 11 as as IN cord-005646-xhx9pzhj 1075 12 in in IN cord-005646-xhx9pzhj 1075 13 intensive intensive JJ cord-005646-xhx9pzhj 1075 14 care care NN cord-005646-xhx9pzhj 1075 15 neonates neonate NNS cord-005646-xhx9pzhj 1075 16 , , , cord-005646-xhx9pzhj 1075 17 may may MD cord-005646-xhx9pzhj 1075 18 produce produce VB cord-005646-xhx9pzhj 1075 19 TSH TSH NNP cord-005646-xhx9pzhj 1075 20 elevation elevation NN cord-005646-xhx9pzhj 1075 21 as as RB cord-005646-xhx9pzhj 1075 22 well well RB cord-005646-xhx9pzhj 1075 23 as as IN cord-005646-xhx9pzhj 1075 24 low low JJ cord-005646-xhx9pzhj 1075 25 T4 T4 NNP cord-005646-xhx9pzhj 1075 26 , , , cord-005646-xhx9pzhj 1075 27 but but CC cord-005646-xhx9pzhj 1075 28 only only RB cord-005646-xhx9pzhj 1075 29 coincidentially coincidentially RB cord-005646-xhx9pzhj 1075 30 , , , cord-005646-xhx9pzhj 1075 31 not not RB cord-005646-xhx9pzhj 1075 32 the the DT cord-005646-xhx9pzhj 1075 33 TSH TSH NNP cord-005646-xhx9pzhj 1075 34 elevation elevation NN cord-005646-xhx9pzhj 1075 35 being be VBG cord-005646-xhx9pzhj 1075 36 the the DT cord-005646-xhx9pzhj 1075 37 consequence consequence NN cord-005646-xhx9pzhj 1075 38 of of IN cord-005646-xhx9pzhj 1075 39 low low JJ cord-005646-xhx9pzhj 1075 40 T4 T4 NNP cord-005646-xhx9pzhj 1075 41 , , , cord-005646-xhx9pzhj 1075 42 thus thus RB cord-005646-xhx9pzhj 1075 43 not not RB cord-005646-xhx9pzhj 1075 44 to to TO cord-005646-xhx9pzhj 1075 45 be be VB cord-005646-xhx9pzhj 1075 46 classified classify VBN cord-005646-xhx9pzhj 1075 47 as as IN cord-005646-xhx9pzhj 1075 48 " " `` cord-005646-xhx9pzhj 1075 49 hypothyroidism hypothyroidism NN cord-005646-xhx9pzhj 1075 50 " " '' cord-005646-xhx9pzhj 1075 51 , , , cord-005646-xhx9pzhj 1075 52 thus thus RB cord-005646-xhx9pzhj 1075 53 not not RB cord-005646-xhx9pzhj 1075 54 indicating indicate VBG cord-005646-xhx9pzhj 1075 55 treatment treatment NN cord-005646-xhx9pzhj 1075 56 . . . cord-005646-xhx9pzhj 1076 1 If if IN cord-005646-xhx9pzhj 1076 2 this this DT cord-005646-xhx9pzhj 1076 3 hypothesis hypothesis NN cord-005646-xhx9pzhj 1076 4 is be VBZ cord-005646-xhx9pzhj 1076 5 right right JJ cord-005646-xhx9pzhj 1076 6 , , , cord-005646-xhx9pzhj 1076 7 we -PRON- PRP cord-005646-xhx9pzhj 1076 8 should should MD cord-005646-xhx9pzhj 1076 9 find find VB cord-005646-xhx9pzhj 1076 10 an an DT cord-005646-xhx9pzhj 1076 11 association association NN cord-005646-xhx9pzhj 1076 12 of of IN cord-005646-xhx9pzhj 1076 13 increasing increase VBG cord-005646-xhx9pzhj 1076 14 pefinatal pefinatal JJ cord-005646-xhx9pzhj 1076 15 stress stress NN cord-005646-xhx9pzhj 1076 16 with with IN cord-005646-xhx9pzhj 1076 17 an an DT cord-005646-xhx9pzhj 1076 18 increasing increase VBG cord-005646-xhx9pzhj 1076 19 number number NN cord-005646-xhx9pzhj 1076 20 of of IN cord-005646-xhx9pzhj 1076 21 neonates neonate NNS cord-005646-xhx9pzhj 1076 22 from from IN cord-005646-xhx9pzhj 1076 23 TSH TSH NNP cord-005646-xhx9pzhj 1076 24 and and CC cord-005646-xhx9pzhj 1076 25 T4 T4 NNP cord-005646-xhx9pzhj 1076 26 normal normal JJ cord-005646-xhx9pzhj 1076 27 via via IN cord-005646-xhx9pzhj 1076 28 TSH TSH NNP cord-005646-xhx9pzhj 1076 29 or or CC cord-005646-xhx9pzhj 1076 30 T4 T4 NNP cord-005646-xhx9pzhj 1076 31 abnormal abnormal JJ cord-005646-xhx9pzhj 1076 32 to to IN cord-005646-xhx9pzhj 1076 33 high high JJ cord-005646-xhx9pzhj 1076 34 TSH tsh NN cord-005646-xhx9pzhj 1076 35 and and CC cord-005646-xhx9pzhj 1076 36 low low JJ cord-005646-xhx9pzhj 1076 37 T4 T4 NNP cord-005646-xhx9pzhj 1076 38 . . . cord-005646-xhx9pzhj 1077 1 Method method NN cord-005646-xhx9pzhj 1077 2 : : : cord-005646-xhx9pzhj 1078 1 In in IN cord-005646-xhx9pzhj 1078 2 the the DT cord-005646-xhx9pzhj 1078 3 newborn newborn JJ cord-005646-xhx9pzhj 1078 4 screening screening NN cord-005646-xhx9pzhj 1078 5 program program NN cord-005646-xhx9pzhj 1078 6 in in IN cord-005646-xhx9pzhj 1078 7 Germa Germa NNP cord-005646-xhx9pzhj 1078 8 W W NNP cord-005646-xhx9pzhj 1078 9 we -PRON- PRP cord-005646-xhx9pzhj 1078 10 determine determine VBP cord-005646-xhx9pzhj 1078 11 primarily primarily RB cord-005646-xhx9pzhj 1078 12 TSH TSH NNP cord-005646-xhx9pzhj 1078 13 , , , cord-005646-xhx9pzhj 1078 14 and and CC cord-005646-xhx9pzhj 1078 15 only only RB cord-005646-xhx9pzhj 1078 16 in in IN cord-005646-xhx9pzhj 1078 17 the the DT cord-005646-xhx9pzhj 1078 18 neonates neonate NNS cord-005646-xhx9pzhj 1078 19 with with IN cord-005646-xhx9pzhj 1078 20 elevated elevated JJ cord-005646-xhx9pzhj 1078 21 TSH tsh NN cord-005646-xhx9pzhj 1078 22 , , , cord-005646-xhx9pzhj 1078 23 in in IN cord-005646-xhx9pzhj 1078 24 addition addition NN cord-005646-xhx9pzhj 1078 25 we -PRON- PRP cord-005646-xhx9pzhj 1078 26 determine determine VBP cord-005646-xhx9pzhj 1078 27 T4 T4 NNP cord-005646-xhx9pzhj 1078 28 . . . cord-005646-xhx9pzhj 1079 1 Thus thus RB cord-005646-xhx9pzhj 1079 2 in in IN cord-005646-xhx9pzhj 1079 3 our -PRON- PRP$ cord-005646-xhx9pzhj 1079 4 study study NN cord-005646-xhx9pzhj 1079 5 we -PRON- PRP cord-005646-xhx9pzhj 1079 6 asked ask VBD cord-005646-xhx9pzhj 1079 7 whether whether IN cord-005646-xhx9pzhj 1079 8 we -PRON- PRP cord-005646-xhx9pzhj 1079 9 find find VBP cord-005646-xhx9pzhj 1079 10 an an DT cord-005646-xhx9pzhj 1079 11 association association NN cord-005646-xhx9pzhj 1079 12 of of IN cord-005646-xhx9pzhj 1079 13 increasing increase VBG cord-005646-xhx9pzhj 1079 14 perinatal perinatal JJ cord-005646-xhx9pzhj 1079 15 stress stress NN cord-005646-xhx9pzhj 1079 16 with with IN cord-005646-xhx9pzhj 1079 17 an an DT cord-005646-xhx9pzhj 1079 18 increasing increase VBG cord-005646-xhx9pzhj 1079 19 number number NN cord-005646-xhx9pzhj 1079 20 of of IN cord-005646-xhx9pzhj 1079 21 neonates neonate NNS cord-005646-xhx9pzhj 1079 22 from from IN cord-005646-xhx9pzhj 1079 23 TSH TSH NNP cord-005646-xhx9pzhj 1079 24 normal normal JJ cord-005646-xhx9pzhj 1079 25 via via IN cord-005646-xhx9pzhj 1079 26 TSH tsh NN cord-005646-xhx9pzhj 1079 27 abnormal abnormal JJ cord-005646-xhx9pzhj 1079 28 while while IN cord-005646-xhx9pzhj 1079 29 T4 T4 NNP cord-005646-xhx9pzhj 1079 30 normal normal JJ cord-005646-xhx9pzhj 1079 31 to to IN cord-005646-xhx9pzhj 1079 32 high high JJ cord-005646-xhx9pzhj 1079 33 TSH tsh NN cord-005646-xhx9pzhj 1079 34 and and CC cord-005646-xhx9pzhj 1079 35 low low JJ cord-005646-xhx9pzhj 1079 36 T4 T4 NNP cord-005646-xhx9pzhj 1079 37 . . . cord-005646-xhx9pzhj 1080 1 Definitions definition NNS cord-005646-xhx9pzhj 1080 2 for for IN cord-005646-xhx9pzhj 1080 3 this this DT cord-005646-xhx9pzhj 1080 4 study study NN cord-005646-xhx9pzhj 1080 5 were be VBD cord-005646-xhx9pzhj 1080 6 : : : cord-005646-xhx9pzhj 1080 7 TSH TSH NNP cord-005646-xhx9pzhj 1080 8 elevation elevation NN cord-005646-xhx9pzhj 1080 9 = = , cord-005646-xhx9pzhj 1080 10 > > XX cord-005646-xhx9pzhj 1081 1 20 20 CD cord-005646-xhx9pzhj 1081 2 mU/1 mU/1 NNP cord-005646-xhx9pzhj 1081 3 ( ( -LRB- cord-005646-xhx9pzhj 1081 4 as as IN cord-005646-xhx9pzhj 1081 5 usual usual JJ cord-005646-xhx9pzhj 1081 6 in in IN cord-005646-xhx9pzhj 1081 7 the the DT cord-005646-xhx9pzhj 1081 8 German german JJ cord-005646-xhx9pzhj 1081 9 screening screening NN cord-005646-xhx9pzhj 1081 10 programs program NNS cord-005646-xhx9pzhj 1081 11 ) ) -RRB- cord-005646-xhx9pzhj 1082 1 , , , cord-005646-xhx9pzhj 1082 2 T4 T4 NNP cord-005646-xhx9pzhj 1082 3 lowered lower VBD cord-005646-xhx9pzhj 1082 4 = = VBZ cord-005646-xhx9pzhj 1082 5 < < XX cord-005646-xhx9pzhj 1082 6 6 6 CD cord-005646-xhx9pzhj 1082 7 p_g p_g NNP cord-005646-xhx9pzhj 1082 8 / / SYM cord-005646-xhx9pzhj 1082 9 dL dl NN cord-005646-xhx9pzhj 1083 1 Perinatal perinatal JJ cord-005646-xhx9pzhj 1083 2 stress stress NN cord-005646-xhx9pzhj 1083 3 score score NN cord-005646-xhx9pzhj 1083 4 was be VBD cord-005646-xhx9pzhj 1083 5 0 0 CD cord-005646-xhx9pzhj 1083 6 or or CC cord-005646-xhx9pzhj 1083 7 1 1 CD cord-005646-xhx9pzhj 1083 8 or or CC cord-005646-xhx9pzhj 1083 9 2 2 CD cord-005646-xhx9pzhj 1083 10 or or CC cord-005646-xhx9pzhj 1083 11 3 3 CD cord-005646-xhx9pzhj 1083 12 in in IN cord-005646-xhx9pzhj 1083 13 dependency dependency NN cord-005646-xhx9pzhj 1083 14 of of IN cord-005646-xhx9pzhj 1083 15 the the DT cord-005646-xhx9pzhj 1083 16 neonate neonate NN cord-005646-xhx9pzhj 1083 17 having have VBG cord-005646-xhx9pzhj 1083 18 stress stress NN cord-005646-xhx9pzhj 1083 19 in in IN cord-005646-xhx9pzhj 1083 20 none none NN cord-005646-xhx9pzhj 1083 21 to to IN cord-005646-xhx9pzhj 1083 22 all all DT cord-005646-xhx9pzhj 1083 23 of of IN cord-005646-xhx9pzhj 1083 24 the the DT cord-005646-xhx9pzhj 1083 25 following following JJ cord-005646-xhx9pzhj 1083 26 three three CD cord-005646-xhx9pzhj 1083 27 categories category NNS cord-005646-xhx9pzhj 1083 28 : : : cord-005646-xhx9pzhj 1083 29 ( ( -LRB- cord-005646-xhx9pzhj 1083 30 a a LS cord-005646-xhx9pzhj 1083 31 ) ) -RRB- cord-005646-xhx9pzhj 1083 32 forceps forceps NNS cord-005646-xhx9pzhj 1083 33 or or CC cord-005646-xhx9pzhj 1083 34 vacuum vacuum NN cord-005646-xhx9pzhj 1083 35 extraction extraction NN cord-005646-xhx9pzhj 1083 36 or or CC cord-005646-xhx9pzhj 1083 37 sectio sectio NNP cord-005646-xhx9pzhj 1083 38 Co Co NNP cord-005646-xhx9pzhj 1083 39 ) ) -RRB- cord-005646-xhx9pzhj 1083 40 birth birth VB cord-005646-xhx9pzhj 1083 41 weight weight NN cord-005646-xhx9pzhj 1083 42 below below IN cord-005646-xhx9pzhj 1083 43 2500 2500 CD cord-005646-xhx9pzhj 1083 44 g g NN cord-005646-xhx9pzhj 1083 45 ( ( -LRB- cord-005646-xhx9pzhj 1083 46 c c NN cord-005646-xhx9pzhj 1083 47 ) ) -RRB- cord-005646-xhx9pzhj 1083 48 at at IN cord-005646-xhx9pzhj 1083 49 the the DT cord-005646-xhx9pzhj 1083 50 5th 5th JJ cord-005646-xhx9pzhj 1083 51 day day NN cord-005646-xhx9pzhj 1083 52 existence existence NN cord-005646-xhx9pzhj 1083 53 of of IN cord-005646-xhx9pzhj 1083 54 a a DT cord-005646-xhx9pzhj 1083 55 relevant relevant JJ cord-005646-xhx9pzhj 1083 56 neonatal neonatal JJ cord-005646-xhx9pzhj 1083 57 disorder disorder NN cord-005646-xhx9pzhj 1083 58 ( ( -LRB- cord-005646-xhx9pzhj 1083 59 RDS RDS NNP cord-005646-xhx9pzhj 1083 60 , , , cord-005646-xhx9pzhj 1083 61 ictems ictem VBZ cord-005646-xhx9pzhj 1083 62 gravis gravis NN cord-005646-xhx9pzhj 1083 63 , , , cord-005646-xhx9pzhj 1083 64 infection infection NN cord-005646-xhx9pzhj 1083 65 / / SYM cord-005646-xhx9pzhj 1083 66 sepsis sepsis NN cord-005646-xhx9pzhj 1083 67 , , , cord-005646-xhx9pzhj 1083 68 vitium vitium FW cord-005646-xhx9pzhj 1083 69 cordis cordis NNP cord-005646-xhx9pzhj 1083 70 with with IN cord-005646-xhx9pzhj 1083 71 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 1083 72 relevance relevance NN cord-005646-xhx9pzhj 1083 73 , , , cord-005646-xhx9pzhj 1083 74 severe severe JJ cord-005646-xhx9pzhj 1083 75 malformation malformation NN cord-005646-xhx9pzhj 1083 76 ) ) -RRB- cord-005646-xhx9pzhj 1083 77 . . . cord-005646-xhx9pzhj 1084 1 Results result NNS cord-005646-xhx9pzhj 1084 2 : : : cord-005646-xhx9pzhj 1085 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 1085 2 data datum NNS cord-005646-xhx9pzhj 1085 3 of of IN cord-005646-xhx9pzhj 1085 4 1131 1131 CD cord-005646-xhx9pzhj 1085 5 neonates neonate NNS cord-005646-xhx9pzhj 1085 6 show show VBP cord-005646-xhx9pzhj 1085 7 a a DT cord-005646-xhx9pzhj 1085 8 high high JJ cord-005646-xhx9pzhj 1085 9 significant significant JJ cord-005646-xhx9pzhj 1085 10 association association NN cord-005646-xhx9pzhj 1085 11 ( ( -LRB- cord-005646-xhx9pzhj 1085 12 chi2 chi2 NNP cord-005646-xhx9pzhj 1085 13 = = SYM cord-005646-xhx9pzhj 1085 14 84 84 CD cord-005646-xhx9pzhj 1085 15 , , , cord-005646-xhx9pzhj 1085 16 p p NN cord-005646-xhx9pzhj 1085 17 < < XX cord-005646-xhx9pzhj 1085 18 0.001 0.001 CD cord-005646-xhx9pzhj 1085 19 ) ) -RRB- cord-005646-xhx9pzhj 1085 20 of of IN cord-005646-xhx9pzhj 1085 21 , , , cord-005646-xhx9pzhj 1085 22 on on IN cord-005646-xhx9pzhj 1085 23 one one CD cord-005646-xhx9pzhj 1085 24 hand hand NN cord-005646-xhx9pzhj 1085 25 , , , cord-005646-xhx9pzhj 1085 26 perinatal perinatal JJ cord-005646-xhx9pzhj 1085 27 stress stress NN cord-005646-xhx9pzhj 1085 28 score score NN cord-005646-xhx9pzhj 1085 29 0 0 CD cord-005646-xhx9pzhj 1085 30 with with IN cord-005646-xhx9pzhj 1085 31 normal normal JJ cord-005646-xhx9pzhj 1085 32 TSH tsh NN cord-005646-xhx9pzhj 1085 33 , , , cord-005646-xhx9pzhj 1085 34 versus versus NN cord-005646-xhx9pzhj 1085 35 , , , cord-005646-xhx9pzhj 1085 36 on on IN cord-005646-xhx9pzhj 1085 37 the the DT cord-005646-xhx9pzhj 1085 38 other other JJ cord-005646-xhx9pzhj 1085 39 hand hand NN cord-005646-xhx9pzhj 1085 40 , , , cord-005646-xhx9pzhj 1085 41 perinatal perinatal JJ cord-005646-xhx9pzhj 1085 42 stress stress NN cord-005646-xhx9pzhj 1085 43 score score NN cord-005646-xhx9pzhj 1085 44 2 2 CD cord-005646-xhx9pzhj 1085 45 or or CC cord-005646-xhx9pzhj 1085 46 3 3 CD cord-005646-xhx9pzhj 1085 47 with with IN cord-005646-xhx9pzhj 1085 48 high high JJ cord-005646-xhx9pzhj 1085 49 TSH tsh NN cord-005646-xhx9pzhj 1085 50 and and CC cord-005646-xhx9pzhj 1085 51 low low JJ cord-005646-xhx9pzhj 1085 52 T4 T4 NNP cord-005646-xhx9pzhj 1085 53 . . . cord-005646-xhx9pzhj 1086 1 Discussion discussion NN cord-005646-xhx9pzhj 1086 2 : : : cord-005646-xhx9pzhj 1087 1 Facing face VBG cord-005646-xhx9pzhj 1087 2 the the DT cord-005646-xhx9pzhj 1087 3 background background NN cord-005646-xhx9pzhj 1087 4 given give VBN cord-005646-xhx9pzhj 1087 5 above above RB cord-005646-xhx9pzhj 1087 6 , , , cord-005646-xhx9pzhj 1087 7 in in IN cord-005646-xhx9pzhj 1087 8 the the DT cord-005646-xhx9pzhj 1087 9 intensive intensive JJ cord-005646-xhx9pzhj 1087 10 care care NN cord-005646-xhx9pzhj 1087 11 newborn newborn JJ cord-005646-xhx9pzhj 1087 12 , , , cord-005646-xhx9pzhj 1087 13 the the DT cord-005646-xhx9pzhj 1087 14 constellation constellation NN cord-005646-xhx9pzhj 1087 15 of of IN cord-005646-xhx9pzhj 1087 16 high high JJ cord-005646-xhx9pzhj 1087 17 TSH TSH NNP cord-005646-xhx9pzhj 1087 18 and and CC cord-005646-xhx9pzhj 1087 19 low low JJ cord-005646-xhx9pzhj 1087 20 T4 T4 NNP cord-005646-xhx9pzhj 1087 21 may may MD cord-005646-xhx9pzhj 1087 22 be be VB cord-005646-xhx9pzhj 1087 23 only only RB cord-005646-xhx9pzhj 1087 24 a a DT cord-005646-xhx9pzhj 1087 25 coincidential coincidential JJ cord-005646-xhx9pzhj 1087 26 addition addition NN cord-005646-xhx9pzhj 1087 27 of of IN cord-005646-xhx9pzhj 1087 28 two two CD cord-005646-xhx9pzhj 1087 29 independent independent JJ cord-005646-xhx9pzhj 1087 30 abnormalities abnormality NNS cord-005646-xhx9pzhj 1087 31 . . . cord-005646-xhx9pzhj 1088 1 In in IN cord-005646-xhx9pzhj 1088 2 tbese tbese JJ cord-005646-xhx9pzhj 1088 3 cases case NNS cord-005646-xhx9pzhj 1088 4 -the -the DT cord-005646-xhx9pzhj 1088 5 high high JJ cord-005646-xhx9pzhj 1088 6 TSH TSH NNP cord-005646-xhx9pzhj 1088 7 not not RB cord-005646-xhx9pzhj 1088 8 being be VBG cord-005646-xhx9pzhj 1088 9 the the DT cord-005646-xhx9pzhj 1088 10 consequence consequence NN cord-005646-xhx9pzhj 1088 11 of of IN cord-005646-xhx9pzhj 1088 12 low low JJ cord-005646-xhx9pzhj 1088 13 T4 T4 NNP cord-005646-xhx9pzhj 1088 14 -the -the DT cord-005646-xhx9pzhj 1088 15 classification classification NN cord-005646-xhx9pzhj 1088 16 as as IN cord-005646-xhx9pzhj 1088 17 " " `` cord-005646-xhx9pzhj 1088 18 hypothyroidism hypothyroidism NN cord-005646-xhx9pzhj 1088 19 " " '' cord-005646-xhx9pzhj 1088 20 is be VBZ cord-005646-xhx9pzhj 1088 21 not not RB cord-005646-xhx9pzhj 1088 22 justified justify VBN cord-005646-xhx9pzhj 1088 23 , , , cord-005646-xhx9pzhj 1088 24 thus thus RB cord-005646-xhx9pzhj 1088 25 a a DT cord-005646-xhx9pzhj 1088 26 therapy therapy NN cord-005646-xhx9pzhj 1088 27 not not RB cord-005646-xhx9pzhj 1088 28 indicated indicate VBN cord-005646-xhx9pzhj 1088 29 . . . cord-005646-xhx9pzhj 1089 1 On on IN cord-005646-xhx9pzhj 1089 2 the the DT cord-005646-xhx9pzhj 1089 3 other other JJ cord-005646-xhx9pzhj 1089 4 hand hand NN cord-005646-xhx9pzhj 1089 5 of of IN cord-005646-xhx9pzhj 1089 6 course course NN cord-005646-xhx9pzhj 1089 7 there there EX cord-005646-xhx9pzhj 1089 8 exist exist VBP cord-005646-xhx9pzhj 1089 9 rare rare JJ cord-005646-xhx9pzhj 1089 10 cases case NNS cord-005646-xhx9pzhj 1089 11 with with IN cord-005646-xhx9pzhj 1089 12 high high JJ cord-005646-xhx9pzhj 1089 13 TSH tsh NN cord-005646-xhx9pzhj 1089 14 as as IN cord-005646-xhx9pzhj 1089 15 consequence consequence NN cord-005646-xhx9pzhj 1089 16 of of IN cord-005646-xhx9pzhj 1089 17 low low JJ cord-005646-xhx9pzhj 1089 18 T4 T4 NNP cord-005646-xhx9pzhj 1089 19 thus thus RB cord-005646-xhx9pzhj 1089 20 with with IN cord-005646-xhx9pzhj 1089 21 hypothyroidism hypothyroidism NN cord-005646-xhx9pzhj 1089 22 tlms tlm NNS cord-005646-xhx9pzhj 1089 23 with with IN cord-005646-xhx9pzhj 1089 24 indication indication NN cord-005646-xhx9pzhj 1089 25 for for IN cord-005646-xhx9pzhj 1089 26 therapy therapy NN cord-005646-xhx9pzhj 1089 27 . . . cord-005646-xhx9pzhj 1090 1 Unfortunately unfortunately RB cord-005646-xhx9pzhj 1090 2 we -PRON- PRP cord-005646-xhx9pzhj 1090 3 have have VBP cord-005646-xhx9pzhj 1090 4 no no DT cord-005646-xhx9pzhj 1090 5 criteria criterion NNS cord-005646-xhx9pzhj 1090 6 , , , cord-005646-xhx9pzhj 1090 7 that that WDT cord-005646-xhx9pzhj 1090 8 enable enable VBP cord-005646-xhx9pzhj 1090 9 a a DT cord-005646-xhx9pzhj 1090 10 certain certain JJ cord-005646-xhx9pzhj 1090 11 discrimination discrimination NN cord-005646-xhx9pzhj 1090 12 of of IN cord-005646-xhx9pzhj 1090 13 these these DT cord-005646-xhx9pzhj 1090 14 two two CD cord-005646-xhx9pzhj 1090 15 categories category NNS cord-005646-xhx9pzhj 1090 16 thus thus RB cord-005646-xhx9pzhj 1090 17 in in IN cord-005646-xhx9pzhj 1090 18 respect respect NN cord-005646-xhx9pzhj 1090 19 to to IN cord-005646-xhx9pzhj 1090 20 the the DT cord-005646-xhx9pzhj 1090 21 question question NN cord-005646-xhx9pzhj 1090 22 of of IN cord-005646-xhx9pzhj 1090 23 therapy therapy NN cord-005646-xhx9pzhj 1090 24 or or CC cord-005646-xhx9pzhj 1090 25 not not RB cord-005646-xhx9pzhj 1090 26 . . . cord-005646-xhx9pzhj 1091 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1091 2 : : : cord-005646-xhx9pzhj 1092 1 Further further JJ cord-005646-xhx9pzhj 1092 2 research research NN cord-005646-xhx9pzhj 1092 3 has have VBZ cord-005646-xhx9pzhj 1092 4 to to TO cord-005646-xhx9pzhj 1092 5 be be VB cord-005646-xhx9pzhj 1092 6 done do VBN cord-005646-xhx9pzhj 1092 7 to to TO cord-005646-xhx9pzhj 1092 8 learn learn VB cord-005646-xhx9pzhj 1092 9 how how WRB cord-005646-xhx9pzhj 1092 10 to to TO cord-005646-xhx9pzhj 1092 11 discriminate discriminate VB cord-005646-xhx9pzhj 1092 12 the the DT cord-005646-xhx9pzhj 1092 13 coincidential coincidential JJ cord-005646-xhx9pzhj 1092 14 high high JJ cord-005646-xhx9pzhj 1092 15 TSH TSH NNP cord-005646-xhx9pzhj 1092 16 and and CC cord-005646-xhx9pzhj 1092 17 low low JJ cord-005646-xhx9pzhj 1092 18 T4 t4 NN cord-005646-xhx9pzhj 1092 19 from from IN cord-005646-xhx9pzhj 1092 20 the the DT cord-005646-xhx9pzhj 1092 21 causal causal JJ cord-005646-xhx9pzhj 1092 22 constellation constellation NN cord-005646-xhx9pzhj 1092 23 of of IN cord-005646-xhx9pzhj 1092 24 high high JJ cord-005646-xhx9pzhj 1092 25 TSH TSH NNP cord-005646-xhx9pzhj 1092 26 and and CC cord-005646-xhx9pzhj 1092 27 low low JJ cord-005646-xhx9pzhj 1092 28 T4 T4 NNP cord-005646-xhx9pzhj 1092 29 . . . cord-005646-xhx9pzhj 1093 1 Until until IN cord-005646-xhx9pzhj 1093 2 we -PRON- PRP cord-005646-xhx9pzhj 1093 3 have have VBP cord-005646-xhx9pzhj 1093 4 certain certain JJ cord-005646-xhx9pzhj 1093 5 discrimination discrimination NN cord-005646-xhx9pzhj 1093 6 criteria criterion NNS cord-005646-xhx9pzhj 1093 7 we -PRON- PRP cord-005646-xhx9pzhj 1093 8 have have VBP cord-005646-xhx9pzhj 1093 9 to to TO cord-005646-xhx9pzhj 1093 10 treat treat VB cord-005646-xhx9pzhj 1093 11 both both DT cord-005646-xhx9pzhj 1093 12 groups group NNS cord-005646-xhx9pzhj 1093 13 of of IN cord-005646-xhx9pzhj 1093 14 neonates neonate NNS cord-005646-xhx9pzhj 1093 15 . . . cord-005646-xhx9pzhj 1094 1 Few few JJ cord-005646-xhx9pzhj 1094 2 studies study NNS cord-005646-xhx9pzhj 1094 3 have have VBP cord-005646-xhx9pzhj 1094 4 focused focus VBN cord-005646-xhx9pzhj 1094 5 on on IN cord-005646-xhx9pzhj 1094 6 FA FA NNP cord-005646-xhx9pzhj 1094 7 composition composition NN cord-005646-xhx9pzhj 1094 8 of of IN cord-005646-xhx9pzhj 1094 9 surfactant surfactant NN cord-005646-xhx9pzhj 1094 10 PC pc NN cord-005646-xhx9pzhj 1094 11 in in IN cord-005646-xhx9pzhj 1094 12 preterm preterm JJ cord-005646-xhx9pzhj 1094 13 infants infant NNS cord-005646-xhx9pzhj 1094 14 before before IN cord-005646-xhx9pzhj 1094 15 and and CC cord-005646-xhx9pzhj 1094 16 after after IN cord-005646-xhx9pzhj 1094 17 surfactant surfactant NN cord-005646-xhx9pzhj 1094 18 therapy therapy NN cord-005646-xhx9pzhj 1094 19 . . . cord-005646-xhx9pzhj 1095 1 Methods method NNS cord-005646-xhx9pzhj 1095 2 : : : cord-005646-xhx9pzhj 1095 3 Tracheal Tracheal NNP cord-005646-xhx9pzhj 1095 4 aspirates aspirate NNS cord-005646-xhx9pzhj 1095 5 were be VBD cord-005646-xhx9pzhj 1095 6 collected collect VBN cord-005646-xhx9pzhj 1095 7 in in IN cord-005646-xhx9pzhj 1095 8 7 7 CD cord-005646-xhx9pzhj 1095 9 venttlated venttlated JJ cord-005646-xhx9pzhj 1095 10 mfants mfant NNS cord-005646-xhx9pzhj 1095 11 from from IN cord-005646-xhx9pzhj 1095 12 birth birth NN cord-005646-xhx9pzhj 1095 13 until until IN cord-005646-xhx9pzhj 1095 14 extubatlon extubatlon NNP cord-005646-xhx9pzhj 1095 15 ( ( -LRB- cord-005646-xhx9pzhj 1095 16 27/7_1 27/7_1 NNP cord-005646-xhx9pzhj 1095 17 /TWk /TWk . cord-005646-xhx9pzhj 1096 1 GA GA NNP cord-005646-xhx9pzhj 1096 2 , , , cord-005646-xhx9pzhj 1096 3 859.+ 859.+ CD cord-005646-xhx9pzhj 1096 4 155 155 CD cord-005646-xhx9pzhj 1096 5 g g NN cord-005646-xhx9pzhj 1096 6 BW BW NNP cord-005646-xhx9pzhj 1096 7 ) ) -RRB- cord-005646-xhx9pzhj 1096 8 . . . cord-005646-xhx9pzhj 1097 1 After after IN cord-005646-xhx9pzhj 1097 2 lipid lipid NN cord-005646-xhx9pzhj 1097 3 extraction extraction NN cord-005646-xhx9pzhj 1097 4 , , , cord-005646-xhx9pzhj 1097 5 t.l.c t.l.c NNP cord-005646-xhx9pzhj 1097 6 , , , cord-005646-xhx9pzhj 1097 7 , , , cord-005646-xhx9pzhj 1097 8 and and CC cord-005646-xhx9pzhj 1097 9 methylation methylation NN cord-005646-xhx9pzhj 1097 10 , , , cord-005646-xhx9pzhj 1097 11 FAs FAs NNP cord-005646-xhx9pzhj 1097 12 of of IN cord-005646-xhx9pzhj 1097 13 PC PC NNP cord-005646-xhx9pzhj 1097 14 were be VBD cord-005646-xhx9pzhj 1097 15 quantified quantify VBN cord-005646-xhx9pzhj 1097 16 by by IN cord-005646-xhx9pzhj 1097 17 gaschromatography gaschromatography NNP cord-005646-xhx9pzhj 1097 18 . . . cord-005646-xhx9pzhj 1098 1 Intralipid Intralipid NNP cord-005646-xhx9pzhj 1098 2 a a DT cord-005646-xhx9pzhj 1098 3 ( ( -LRB- cord-005646-xhx9pzhj 1098 4 53.2 53.2 CD cord-005646-xhx9pzhj 1098 5 % % NN cord-005646-xhx9pzhj 1098 6 linoleic linoleic NN cord-005646-xhx9pzhj 1098 7 acid,18:2•6 acid,18:2•6 CD cord-005646-xhx9pzhj 1098 8 ) ) -RRB- cord-005646-xhx9pzhj 1098 9 was be VBD cord-005646-xhx9pzhj 1098 10 started start VBN cord-005646-xhx9pzhj 1098 11 48h 48h NNS cord-005646-xhx9pzhj 1098 12 after after IN cord-005646-xhx9pzhj 1098 13 birth birth NN cord-005646-xhx9pzhj 1098 14 . . . cord-005646-xhx9pzhj 1099 1 Results result NNS cord-005646-xhx9pzhj 1099 2 : : : cord-005646-xhx9pzhj 1100 1 Six six CD cord-005646-xhx9pzhj 1100 2 infants infant NNS cord-005646-xhx9pzhj 1100 3 developed develop VBD cord-005646-xhx9pzhj 1100 4 respiratory respiratory JJ cord-005646-xhx9pzhj 1100 5 distress distress NN cord-005646-xhx9pzhj 1100 6 syndrome syndrome NN cord-005646-xhx9pzhj 1100 7 ( ( -LRB- cord-005646-xhx9pzhj 1100 8 RDS RDS NNP cord-005646-xhx9pzhj 1100 9 ) ) -RRB- cord-005646-xhx9pzhj 1100 10 and and CC cord-005646-xhx9pzhj 1100 11 received receive VBD cord-005646-xhx9pzhj 1100 12 Survanta Survanta NNP cord-005646-xhx9pzhj 1100 13 R R NNP cord-005646-xhx9pzhj 1100 14 i00mg i00mg NNP cord-005646-xhx9pzhj 1100 15 / / SYM cord-005646-xhx9pzhj 1100 16 kg kg NNP cord-005646-xhx9pzhj 1100 17 ( ( -LRB- cord-005646-xhx9pzhj 1100 18 SR SR NNP cord-005646-xhx9pzhj 1100 19 ) ) -RRB- cord-005646-xhx9pzhj 1100 20 , , , cord-005646-xhx9pzhj 1100 21 all all DT cord-005646-xhx9pzhj 1100 22 doses dose NNS cord-005646-xhx9pzhj 1100 23 within within IN cord-005646-xhx9pzhj 1100 24 18h 18h NNS cord-005646-xhx9pzhj 1100 25 after after IN cord-005646-xhx9pzhj 1100 26 birth birth NN cord-005646-xhx9pzhj 1101 1 ( ( -LRB- cord-005646-xhx9pzhj 1101 2 Ix Ix NNP cord-005646-xhx9pzhj 1101 3 S S NNP cord-005646-xhx9pzhj 1101 4 R r NN cord-005646-xhx9pzhj 1101 5 n n NN cord-005646-xhx9pzhj 1101 6 = = NN cord-005646-xhx9pzhj 1101 7 l l NN cord-005646-xhx9pzhj 1101 8 , , , cord-005646-xhx9pzhj 1101 9 2x 2x NNP cord-005646-xhx9pzhj 1101 10 S s NN cord-005646-xhx9pzhj 1102 1 r~ r~ : cord-005646-xhx9pzhj 1102 2 n=3 n=3 NN cord-005646-xhx9pzhj 1102 3 , , , cord-005646-xhx9pzhj 1102 4 3x 3x NNP cord-005646-xhx9pzhj 1102 5 S s NN cord-005646-xhx9pzhj 1102 6 R r NN cord-005646-xhx9pzhj 1102 7 n=2 n=2 NNS cord-005646-xhx9pzhj 1102 8 ) ) -RRB- cord-005646-xhx9pzhj 1102 9 . . . cord-005646-xhx9pzhj 1103 1 One one CD cord-005646-xhx9pzhj 1103 2 child child NN cord-005646-xhx9pzhj 1103 3 did do VBD cord-005646-xhx9pzhj 1103 4 not not RB cord-005646-xhx9pzhj 1103 5 develop develop VB cord-005646-xhx9pzhj 1103 6 RDS RDS NNP cord-005646-xhx9pzhj 1103 7 . . . cord-005646-xhx9pzhj 1104 1 In in IN cord-005646-xhx9pzhj 1104 2 alt alt JJ cord-005646-xhx9pzhj 1104 3 patients patient NNS cord-005646-xhx9pzhj 1104 4 , , , cord-005646-xhx9pzhj 1104 5 the the DT cord-005646-xhx9pzhj 1104 6 patmitate patmitate NN cord-005646-xhx9pzhj 1104 7 % % NN cord-005646-xhx9pzhj 1104 8 in in IN cord-005646-xhx9pzhj 1104 9 PC pc NN cord-005646-xhx9pzhj 1104 10 was be VBD cord-005646-xhx9pzhj 1104 11 ~ ~ NFP cord-005646-xhx9pzhj 1104 12 65 65 CD cord-005646-xhx9pzhj 1104 13 % % NN cord-005646-xhx9pzhj 1104 14 ( ( -LRB- cord-005646-xhx9pzhj 1104 15 before before IN cord-005646-xhx9pzhj 1104 16 Sr<=natural sr<=natural JJ cord-005646-xhx9pzhj 1104 17 composition composition NN cord-005646-xhx9pzhj 1104 18 ) ) -RRB- cord-005646-xhx9pzhj 1104 19 , , , cord-005646-xhx9pzhj 1104 20 increased increase VBD cord-005646-xhx9pzhj 1104 21 to to IN cord-005646-xhx9pzhj 1104 22 ~ ~ CD cord-005646-xhx9pzhj 1104 23 85 85 CD cord-005646-xhx9pzhj 1104 24 % % NN cord-005646-xhx9pzhj 1104 25 after after IN cord-005646-xhx9pzhj 1104 26 S S NNP cord-005646-xhx9pzhj 1104 27 R R NNP cord-005646-xhx9pzhj 1104 28 , , , cord-005646-xhx9pzhj 1104 29 and and CC cord-005646-xhx9pzhj 1104 30 remained remain VBD cord-005646-xhx9pzhj 1104 31 > > XX cord-005646-xhx9pzhj 1104 32 80 80 CD cord-005646-xhx9pzhj 1104 33 % % NN cord-005646-xhx9pzhj 1104 34 for for IN cord-005646-xhx9pzhj 1104 35 i5h i5h NNP cord-005646-xhx9pzhj 1104 36 after after IN cord-005646-xhx9pzhj 1104 37 lx lx NNP cord-005646-xhx9pzhj 1104 38 S S NNP cord-005646-xhx9pzhj 1104 39 a a NNP cord-005646-xhx9pzhj 1104 40 , , , cord-005646-xhx9pzhj 1104 41 22.3.+I1.8h 22.3.+i1.8h CD cord-005646-xhx9pzhj 1104 42 after after IN cord-005646-xhx9pzhj 1104 43 2x 2x CD cord-005646-xhx9pzhj 1104 44 , , , cord-005646-xhx9pzhj 1104 45 and and CC cord-005646-xhx9pzhj 1104 46 38.5.+3.3h 38.5.+3.3h CD cord-005646-xhx9pzhj 1104 47 after after IN cord-005646-xhx9pzhj 1104 48 3 3 CD cord-005646-xhx9pzhj 1104 49 doses dose NNS cord-005646-xhx9pzhj 1104 50 . . . cord-005646-xhx9pzhj 1105 1 In in IN cord-005646-xhx9pzhj 1105 2 4 4 CD cord-005646-xhx9pzhj 1105 3 patients patient NNS cord-005646-xhx9pzhj 1105 4 , , , cord-005646-xhx9pzhj 1105 5 intubated intubate VBN cord-005646-xhx9pzhj 1105 6 long long RB cord-005646-xhx9pzhj 1105 7 enough enough RB cord-005646-xhx9pzhj 1105 8 , , , cord-005646-xhx9pzhj 1105 9 the the DT cord-005646-xhx9pzhj 1105 10 palmitate palmitate NN cord-005646-xhx9pzhj 1105 11 % % NN cord-005646-xhx9pzhj 1105 12 decreased decrease VBD cord-005646-xhx9pzhj 1105 13 with with IN cord-005646-xhx9pzhj 1105 14 a a DT cord-005646-xhx9pzhj 1105 15 half half JJ cord-005646-xhx9pzhj 1105 16 - - HYPH cord-005646-xhx9pzhj 1105 17 life life NN cord-005646-xhx9pzhj 1105 18 of of IN cord-005646-xhx9pzhj 1105 19 78.7_+42.8h 78.7_+42.8h CD cord-005646-xhx9pzhj 1105 20 to to IN cord-005646-xhx9pzhj 1105 21 a a DT cord-005646-xhx9pzhj 1105 22 new new JJ cord-005646-xhx9pzhj 1105 23 plateau plateau NN cord-005646-xhx9pzhj 1105 24 which which WDT cord-005646-xhx9pzhj 1105 25 was be VBD cord-005646-xhx9pzhj 1105 26 still still RB cord-005646-xhx9pzhj 1105 27 higher high JJR cord-005646-xhx9pzhj 1105 28 than than IN cord-005646-xhx9pzhj 1105 29 baseline baseline NN cord-005646-xhx9pzhj 1105 30 after after IN cord-005646-xhx9pzhj 1105 31 1 1 CD cord-005646-xhx9pzhj 1105 32 week week NN cord-005646-xhx9pzhj 1105 33 . . . cord-005646-xhx9pzhj 1106 1 Linoleic linoleic NN cord-005646-xhx9pzhj 1106 2 acid acid NN cord-005646-xhx9pzhj 1106 3 % % NN cord-005646-xhx9pzhj 1106 4 was be VBD cord-005646-xhx9pzhj 1106 5 5.85_+2.3 5.85_+2.3 CD cord-005646-xhx9pzhj 1106 6 ( ( -LRB- cord-005646-xhx9pzhj 1106 7 with with IN cord-005646-xhx9pzhj 1106 8 RDS RDS NNP cord-005646-xhx9pzhj 1106 9 ) ) -RRB- cord-005646-xhx9pzhj 1106 10 , , , cord-005646-xhx9pzhj 1106 11 decreased decrease VBD cord-005646-xhx9pzhj 1106 12 after after IN cord-005646-xhx9pzhj 1106 13 S S NNP cord-005646-xhx9pzhj 1106 14 r~ r~ : cord-005646-xhx9pzhj 1106 15 and and CC cord-005646-xhx9pzhj 1106 16 returned return VBD cord-005646-xhx9pzhj 1106 17 to to IN cord-005646-xhx9pzhj 1106 18 baseline baseline NN cord-005646-xhx9pzhj 1106 19 due due IN cord-005646-xhx9pzhj 1106 20 to to IN cord-005646-xhx9pzhj 1106 21 the the DT cord-005646-xhx9pzhj 1106 22 decrease decrease NN cord-005646-xhx9pzhj 1106 23 in in IN cord-005646-xhx9pzhj 1106 24 patmitate patmitate NN cord-005646-xhx9pzhj 1106 25 % % NN cord-005646-xhx9pzhj 1106 26 . . . cord-005646-xhx9pzhj 1107 1 Thereafter thereafter RB cord-005646-xhx9pzhj 1107 2 the the DT cord-005646-xhx9pzhj 1107 3 linoleic linoleic JJ cord-005646-xhx9pzhj 1107 4 acid acid NN cord-005646-xhx9pzhj 1107 5 % % NN cord-005646-xhx9pzhj 1107 6 increased increase VBD cord-005646-xhx9pzhj 1107 7 linearly linearly RB cord-005646-xhx9pzhj 1107 8 with with IN cord-005646-xhx9pzhj 1107 9 0.021 0.021 CD cord-005646-xhx9pzhj 1107 10 % % NN cord-005646-xhx9pzhj 1107 11 per per IN cord-005646-xhx9pzhj 1107 12 h h NN cord-005646-xhx9pzhj 1107 13 , , , cord-005646-xhx9pzhj 1107 14 in in IN cord-005646-xhx9pzhj 1107 15 1 1 CD cord-005646-xhx9pzhj 1107 16 patient patient NN cord-005646-xhx9pzhj 1107 17 even even RB cord-005646-xhx9pzhj 1107 18 up up IN cord-005646-xhx9pzhj 1107 19 to to IN cord-005646-xhx9pzhj 1107 20 15.1 15.1 CD cord-005646-xhx9pzhj 1107 21 % % NN cord-005646-xhx9pzhj 1107 22 . . . cord-005646-xhx9pzhj 1108 1 Other other JJ cord-005646-xhx9pzhj 1108 2 FAs fa NNS cord-005646-xhx9pzhj 1108 3 did do VBD cord-005646-xhx9pzhj 1108 4 not not RB cord-005646-xhx9pzhj 1108 5 increase increase VB cord-005646-xhx9pzhj 1108 6 after after IN cord-005646-xhx9pzhj 1108 7 return return NN cord-005646-xhx9pzhj 1108 8 to to IN cord-005646-xhx9pzhj 1108 9 baseline baseline NN cord-005646-xhx9pzhj 1108 10 . . . cord-005646-xhx9pzhj 1109 1 In in IN cord-005646-xhx9pzhj 1109 2 neonatal neonatal JJ cord-005646-xhx9pzhj 1109 3 medicine medicine NN cord-005646-xhx9pzhj 1109 4 the the DT cord-005646-xhx9pzhj 1109 5 current current JJ cord-005646-xhx9pzhj 1109 6 parameters parameter NNS cord-005646-xhx9pzhj 1109 7 , , , cord-005646-xhx9pzhj 1109 8 arterial arterial JJ cord-005646-xhx9pzhj 1109 9 oxygen oxygen NN cord-005646-xhx9pzhj 1109 10 saturation saturation NN cord-005646-xhx9pzhj 1109 11 and and CC cord-005646-xhx9pzhj 1109 12 arterial arterial JJ cord-005646-xhx9pzhj 1109 13 oxygen oxygen NN cord-005646-xhx9pzhj 1109 14 pressure pressure NN cord-005646-xhx9pzhj 1109 15 , , , cord-005646-xhx9pzhj 1109 16 are be VBP cord-005646-xhx9pzhj 1109 17 poor poor JJ cord-005646-xhx9pzhj 1109 18 indicators indicator NNS cord-005646-xhx9pzhj 1109 19 for for IN cord-005646-xhx9pzhj 1109 20 oxygen oxygen NN cord-005646-xhx9pzhj 1109 21 delivery delivery NN cord-005646-xhx9pzhj 1109 22 and and CC cord-005646-xhx9pzhj 1109 23 oxygen oxygen NN cord-005646-xhx9pzhj 1109 24 demand demand NN cord-005646-xhx9pzhj 1109 25 . . . cord-005646-xhx9pzhj 1110 1 The the DT cord-005646-xhx9pzhj 1110 2 purpose purpose NN cord-005646-xhx9pzhj 1110 3 of of IN cord-005646-xhx9pzhj 1110 4 this this DT cord-005646-xhx9pzhj 1110 5 study study NN cord-005646-xhx9pzhj 1110 6 was be VBD cord-005646-xhx9pzhj 1110 7 to to TO cord-005646-xhx9pzhj 1110 8 obtain obtain VB cord-005646-xhx9pzhj 1110 9 venous venous JJ cord-005646-xhx9pzhj 1110 10 blood blood NN cord-005646-xhx9pzhj 1110 11 samples sample NNS cord-005646-xhx9pzhj 1110 12 from from IN cord-005646-xhx9pzhj 1110 13 the the DT cord-005646-xhx9pzhj 1110 14 inferior inferior JJ cord-005646-xhx9pzhj 1110 15 vena vena FW cord-005646-xhx9pzhj 1110 16 cava cava NN cord-005646-xhx9pzhj 1110 17 in in IN cord-005646-xhx9pzhj 1110 18 stable stable JJ cord-005646-xhx9pzhj 1110 19 neonates neonate NNS cord-005646-xhx9pzhj 1110 20 with with IN cord-005646-xhx9pzhj 1110 21 respiratory respiratory JJ cord-005646-xhx9pzhj 1110 22 failure failure NN cord-005646-xhx9pzhj 1110 23 and and CC cord-005646-xhx9pzhj 1110 24 to to TO cord-005646-xhx9pzhj 1110 25 determine determine VB cord-005646-xhx9pzhj 1110 26 a a DT cord-005646-xhx9pzhj 1110 27 parameter parameter NN cord-005646-xhx9pzhj 1110 28 that that WDT cord-005646-xhx9pzhj 1110 29 reflects reflect VBZ cord-005646-xhx9pzhj 1110 30 more more RBR cord-005646-xhx9pzhj 1110 31 adequately adequately RB cord-005646-xhx9pzhj 1110 32 the the DT cord-005646-xhx9pzhj 1110 33 balance balance NN cord-005646-xhx9pzhj 1110 34 between between IN cord-005646-xhx9pzhj 1110 35 oxygen oxygen NN cord-005646-xhx9pzhj 1110 36 delivery delivery NN cord-005646-xhx9pzhj 1110 37 and and CC cord-005646-xhx9pzhj 1110 38 oxygen oxygen NN cord-005646-xhx9pzhj 1110 39 demand demand NN cord-005646-xhx9pzhj 1110 40 . . . cord-005646-xhx9pzhj 1110 41 " " '' cord-005646-xhx9pzhj 1111 1 l l NNP cord-005646-xhx9pzhj 1111 2 ~ ~ NNP cord-005646-xhx9pzhj 1111 3 e e NNP cord-005646-xhx9pzhj 1111 4 study study NN cord-005646-xhx9pzhj 1111 5 included include VBD cord-005646-xhx9pzhj 1111 6 22 22 CD cord-005646-xhx9pzhj 1111 7 neonates neonate NNS cord-005646-xhx9pzhj 1111 8 requiring require VBG cord-005646-xhx9pzhj 1111 9 mechanical mechanical JJ cord-005646-xhx9pzhj 1111 10 ventilation ventilation NN cord-005646-xhx9pzhj 1111 11 tbr tbr NNP cord-005646-xhx9pzhj 1111 12 severe severe JJ cord-005646-xhx9pzhj 1111 13 respiratory respiratory JJ cord-005646-xhx9pzhj 1111 14 insufficiency insufficiency NN cord-005646-xhx9pzhj 1111 15 . . . cord-005646-xhx9pzhj 1112 1 An an DT cord-005646-xhx9pzhj 1112 2 umbilical umbilical JJ cord-005646-xhx9pzhj 1112 3 venous venous JJ cord-005646-xhx9pzhj 1112 4 and and CC cord-005646-xhx9pzhj 1112 5 arterial arterial JJ cord-005646-xhx9pzhj 1112 6 catheter catheter NN cord-005646-xhx9pzhj 1112 7 were be VBD cord-005646-xhx9pzhj 1112 8 inserted insert VBN cord-005646-xhx9pzhj 1112 9 in in IN cord-005646-xhx9pzhj 1112 10 the the DT cord-005646-xhx9pzhj 1112 11 inferior inferior JJ cord-005646-xhx9pzhj 1112 12 vena vena FW cord-005646-xhx9pzhj 1112 13 cava cava NN cord-005646-xhx9pzhj 1112 14 and and CC cord-005646-xhx9pzhj 1112 15 in in IN cord-005646-xhx9pzhj 1112 16 the the DT cord-005646-xhx9pzhj 1112 17 aorta aorta NN cord-005646-xhx9pzhj 1112 18 respectively respectively RB cord-005646-xhx9pzhj 1112 19 . . . cord-005646-xhx9pzhj 1113 1 Paired pair VBN cord-005646-xhx9pzhj 1113 2 blood blood NN cord-005646-xhx9pzhj 1113 3 samples sample NNS cord-005646-xhx9pzhj 1113 4 were be VBD cord-005646-xhx9pzhj 1113 5 obtained obtain VBN cord-005646-xhx9pzhj 1113 6 at at IN cord-005646-xhx9pzhj 1113 7 the the DT cord-005646-xhx9pzhj 1113 8 time time NN cord-005646-xhx9pzhj 1113 9 that that WDT cord-005646-xhx9pzhj 1113 10 the the DT cord-005646-xhx9pzhj 1113 11 patients patient NNS cord-005646-xhx9pzhj 1113 12 were be VBD cord-005646-xhx9pzhj 1113 13 hemodynamically hemodynamically RB cord-005646-xhx9pzhj 1113 14 stable stable JJ cord-005646-xhx9pzhj 1113 15 . . . cord-005646-xhx9pzhj 1114 1 Fifty fifty CD cord-005646-xhx9pzhj 1114 2 paired pair VBN cord-005646-xhx9pzhj 1114 3 arterial arterial NN cord-005646-xhx9pzhj 1114 4 and and CC cord-005646-xhx9pzhj 1114 5 mixed mixed JJ cord-005646-xhx9pzhj 1114 6 venous venous JJ cord-005646-xhx9pzhj 1114 7 blood blood NN cord-005646-xhx9pzhj 1114 8 samples sample NNS cord-005646-xhx9pzhj 1114 9 were be VBD cord-005646-xhx9pzhj 1114 10 analyzed analyze VBN cord-005646-xhx9pzhj 1114 11 . . . cord-005646-xhx9pzhj 1115 1 1Jnear 1jnear CD cord-005646-xhx9pzhj 1115 2 regression regression NN cord-005646-xhx9pzhj 1115 3 analysis analysis NN cord-005646-xhx9pzhj 1115 4 showed show VBD cord-005646-xhx9pzhj 1115 5 the the DT cord-005646-xhx9pzhj 1115 6 following follow VBG cord-005646-xhx9pzhj 1115 7 correlations correlation NNS cord-005646-xhx9pzhj 1115 8 : : : cord-005646-xhx9pzhj 1115 9 In in IN cord-005646-xhx9pzhj 1115 10 a a DT cord-005646-xhx9pzhj 1115 11 neonatal neonatal JJ cord-005646-xhx9pzhj 1115 12 intensive intensive JJ cord-005646-xhx9pzhj 1115 13 care care NN cord-005646-xhx9pzhj 1115 14 unit unit NN cord-005646-xhx9pzhj 1115 15 adjacent adjacent JJ cord-005646-xhx9pzhj 1115 16 to to IN cord-005646-xhx9pzhj 1115 17 a a DT cord-005646-xhx9pzhj 1115 18 delivery delivery NN cord-005646-xhx9pzhj 1115 19 room room NN cord-005646-xhx9pzhj 1115 20 caring care VBG cord-005646-xhx9pzhj 1115 21 for for IN cord-005646-xhx9pzhj 1115 22 4000 4000 CD cord-005646-xhx9pzhj 1115 23 mothers mother NNS cord-005646-xhx9pzhj 1115 24 per per IN cord-005646-xhx9pzhj 1115 25 year year NN cord-005646-xhx9pzhj 1115 26 , , , cord-005646-xhx9pzhj 1115 27 ( ( -LRB- cord-005646-xhx9pzhj 1115 28 with with IN cord-005646-xhx9pzhj 1115 29 a a DT cord-005646-xhx9pzhj 1115 30 referral referral NN cord-005646-xhx9pzhj 1115 31 of of IN cord-005646-xhx9pzhj 1115 32 400 400 CD cord-005646-xhx9pzhj 1115 33 mostly mostly RB cord-005646-xhx9pzhj 1115 34 for for IN cord-005646-xhx9pzhj 1115 35 preterm preterm JJR cord-005646-xhx9pzhj 1115 36 delivery delivery NN cord-005646-xhx9pzhj 1115 37 ) ) -RRB- cord-005646-xhx9pzhj 1115 38 , , , cord-005646-xhx9pzhj 1115 39 virtually virtually RB cord-005646-xhx9pzhj 1115 40 every every DT cord-005646-xhx9pzhj 1115 41 neonate neonate NN cord-005646-xhx9pzhj 1116 1 < < XX cord-005646-xhx9pzhj 1116 2 lS00 lS00 HYPH cord-005646-xhx9pzhj 1116 3 g g NNP cord-005646-xhx9pzhj 1116 4 was be VBD cord-005646-xhx9pzhj 1116 5 seen see VBN cord-005646-xhx9pzhj 1116 6 by by IN cord-005646-xhx9pzhj 1116 7 the the DT cord-005646-xhx9pzhj 1116 8 same same JJ cord-005646-xhx9pzhj 1116 9 ophtalmologist ophtalmologist NN cord-005646-xhx9pzhj 1116 10 , , , cord-005646-xhx9pzhj 1116 11 J.O. J.O. NNP cord-005646-xhx9pzhj 1117 1 The the DT cord-005646-xhx9pzhj 1117 2 incidence incidence NN cord-005646-xhx9pzhj 1117 3 of of IN cord-005646-xhx9pzhj 1117 4 retinopathy retinopathy NN cord-005646-xhx9pzhj 1117 5 of of IN cord-005646-xhx9pzhj 1117 6 prematurity prematurity NN cord-005646-xhx9pzhj 1117 7 ( ( -LRB- cord-005646-xhx9pzhj 1117 8 ROP ROP NNP cord-005646-xhx9pzhj 1117 9 ) ) -RRB- cord-005646-xhx9pzhj 1117 10 was be VBD cord-005646-xhx9pzhj 1117 11 in in IN cord-005646-xhx9pzhj 1117 12 1976 1976 CD cord-005646-xhx9pzhj 1117 13 - - SYM cord-005646-xhx9pzhj 1117 14 80 80 CD cord-005646-xhx9pzhj 1117 15 of of IN cord-005646-xhx9pzhj 1117 16 II ii CD cord-005646-xhx9pzhj 1117 17 cases case NNS cord-005646-xhx9pzhj 1117 18 ( ( -LRB- cord-005646-xhx9pzhj 1117 19 464 464 CD cord-005646-xhx9pzhj 1117 20 preterms preterm NNS cord-005646-xhx9pzhj 1118 1 < < XX cord-005646-xhx9pzhj 1118 2 lS00 lS00 HYPH cord-005646-xhx9pzhj 1118 3 g g NNP cord-005646-xhx9pzhj 1118 4 with with IN cord-005646-xhx9pzhj 1118 5 58 58 CD cord-005646-xhx9pzhj 1118 6 % % NN cord-005646-xhx9pzhj 1118 7 surviving survive VBG cord-005646-xhx9pzhj 1118 8 to to TO cord-005646-xhx9pzhj 1118 9 discharge discharge VB cord-005646-xhx9pzhj 1118 10 , , , cord-005646-xhx9pzhj 1118 11 and and CC cord-005646-xhx9pzhj 1118 12 4 4 CD cord-005646-xhx9pzhj 1118 13 % % NN cord-005646-xhx9pzhj 1118 14 ROP rop NN cord-005646-xhx9pzhj 1118 15 in in IN cord-005646-xhx9pzhj 1118 16 survivors survivor NNS cord-005646-xhx9pzhj 1118 17 ; ; : cord-005646-xhx9pzhj 1118 18 8 8 CD cord-005646-xhx9pzhj 1118 19 % % NN cord-005646-xhx9pzhj 1118 20 if if IN cord-005646-xhx9pzhj 1118 21 less less JJR cord-005646-xhx9pzhj 1118 22 than than IN cord-005646-xhx9pzhj 1118 23 30 30 CD cord-005646-xhx9pzhj 1118 24 weeks week NNS cord-005646-xhx9pzhj 1118 25 ) ) -RRB- cord-005646-xhx9pzhj 1118 26 . . . cord-005646-xhx9pzhj 1119 1 In in IN cord-005646-xhx9pzhj 1119 2 1987 1987 CD cord-005646-xhx9pzhj 1119 3 - - SYM cord-005646-xhx9pzhj 1119 4 1993 1993 CD cord-005646-xhx9pzhj 1119 5 , , , cord-005646-xhx9pzhj 1119 6 57 57 CD cord-005646-xhx9pzhj 1119 7 cases case NNS cord-005646-xhx9pzhj 1119 8 of of IN cord-005646-xhx9pzhj 1119 9 ROP ROP NNP cord-005646-xhx9pzhj 1119 10 were be VBD cord-005646-xhx9pzhj 1119 11 diagnosed diagnose VBN cord-005646-xhx9pzhj 1119 12 by by IN cord-005646-xhx9pzhj 1119 13 the the DT cord-005646-xhx9pzhj 1119 14 same same JJ cord-005646-xhx9pzhj 1119 15 ophtalmologist ophtalmologist NN cord-005646-xhx9pzhj 1119 16 . . . cord-005646-xhx9pzhj 1120 1 679 679 CD cord-005646-xhx9pzhj 1120 2 were be VBD cord-005646-xhx9pzhj 1120 3 born bear VBN cord-005646-xhx9pzhj 1120 4 at at IN cord-005646-xhx9pzhj 1120 5 less less JJR cord-005646-xhx9pzhj 1120 6 than than IN cord-005646-xhx9pzhj 1120 7 30 30 CD cord-005646-xhx9pzhj 1120 8 weeks week NNS cord-005646-xhx9pzhj 1120 9 , , , cord-005646-xhx9pzhj 1120 10 of of IN cord-005646-xhx9pzhj 1120 11 which which WDT cord-005646-xhx9pzhj 1120 12 452 452 CD cord-005646-xhx9pzhj 1120 13 ( ( -LRB- cord-005646-xhx9pzhj 1120 14 66 66 CD cord-005646-xhx9pzhj 1120 15 % % NN cord-005646-xhx9pzhj 1120 16 ) ) -RRB- cord-005646-xhx9pzhj 1120 17 survived survive VBD cord-005646-xhx9pzhj 1120 18 to to TO cord-005646-xhx9pzhj 1120 19 discharge discharge VB cord-005646-xhx9pzhj 1120 20 , , , cord-005646-xhx9pzhj 1120 21 and and CC cord-005646-xhx9pzhj 1120 22 among among IN cord-005646-xhx9pzhj 1120 23 those those DT cord-005646-xhx9pzhj 1120 24 survivors survivor NNS cord-005646-xhx9pzhj 1120 25 , , , cord-005646-xhx9pzhj 1120 26 ROP ROP NNP cord-005646-xhx9pzhj 1120 27 was be VBD cord-005646-xhx9pzhj 1120 28 present present JJ cord-005646-xhx9pzhj 1120 29 in in IN cord-005646-xhx9pzhj 1120 30 53 53 CD cord-005646-xhx9pzhj 1120 31 ( ( -LRB- cord-005646-xhx9pzhj 1120 32 12 12 CD cord-005646-xhx9pzhj 1120 33 % % NN cord-005646-xhx9pzhj 1120 34 ) ) -RRB- cord-005646-xhx9pzhj 1120 35 , , , cord-005646-xhx9pzhj 1120 36 with with IN cord-005646-xhx9pzhj 1120 37 rates rate NNS cord-005646-xhx9pzhj 1120 38 varying vary VBG cord-005646-xhx9pzhj 1120 39 from from IN cord-005646-xhx9pzhj 1120 40 58 58 CD cord-005646-xhx9pzhj 1120 41 % % NN cord-005646-xhx9pzhj 1120 42 at at IN cord-005646-xhx9pzhj 1120 43 24 24 CD cord-005646-xhx9pzhj 1120 44 weeks week NNS cord-005646-xhx9pzhj 1120 45 to to IN cord-005646-xhx9pzhj 1120 46 5 5 CD cord-005646-xhx9pzhj 1120 47 % % NN cord-005646-xhx9pzhj 1120 48 at at IN cord-005646-xhx9pzhj 1120 49 29 29 CD cord-005646-xhx9pzhj 1120 50 . . . cord-005646-xhx9pzhj 1121 1 Objective objective NN cord-005646-xhx9pzhj 1121 2 : : : cord-005646-xhx9pzhj 1121 3 to to TO cord-005646-xhx9pzhj 1121 4 compare compare VB cord-005646-xhx9pzhj 1121 5 a a DT cord-005646-xhx9pzhj 1121 6 method method NN cord-005646-xhx9pzhj 1121 7 of of IN cord-005646-xhx9pzhj 1121 8 teicoplanine teicoplanine NN cord-005646-xhx9pzhj 1121 9 ( ( -LRB- cord-005646-xhx9pzhj 1121 10 Teico Teico NNP cord-005646-xhx9pzhj 1121 11 ) ) -RRB- cord-005646-xhx9pzhj 1121 12 infusion infusion NN cord-005646-xhx9pzhj 1121 13 using use VBG cord-005646-xhx9pzhj 1121 14 an an DT cord-005646-xhx9pzhj 1121 15 electrical electrical JJ cord-005646-xhx9pzhj 1121 16 syringe syringe NN cord-005646-xhx9pzhj 1121 17 - - HYPH cord-005646-xhx9pzhj 1121 18 pump pump NN cord-005646-xhx9pzhj 1121 19 with with IN cord-005646-xhx9pzhj 1121 20 a a DT cord-005646-xhx9pzhj 1121 21 manual manual JJ cord-005646-xhx9pzhj 1121 22 injection injection NN cord-005646-xhx9pzhj 1121 23 . . . cord-005646-xhx9pzhj 1122 1 Methods method NNS cord-005646-xhx9pzhj 1122 2 : : : cord-005646-xhx9pzhj 1122 3 infusion infusion NN cord-005646-xhx9pzhj 1122 4 of of IN cord-005646-xhx9pzhj 1122 5 Teico Teico NNP cord-005646-xhx9pzhj 1122 6 was be VBD cord-005646-xhx9pzhj 1122 7 simulated simulate VBN cord-005646-xhx9pzhj 1122 8 through through IN cord-005646-xhx9pzhj 1122 9 a a DT cord-005646-xhx9pzhj 1122 10 standart standart JJ cord-005646-xhx9pzhj 1122 11 neonatal neonatal JJ cord-005646-xhx9pzhj 1122 12 I.V. I.V. NNP cord-005646-xhx9pzhj 1122 13 system system NN cord-005646-xhx9pzhj 1122 14 . . . cord-005646-xhx9pzhj 1123 1 The the DT cord-005646-xhx9pzhj 1123 2 infusion infusion NN cord-005646-xhx9pzhj 1123 3 system system NN cord-005646-xhx9pzhj 1123 4 consisted consist VBD cord-005646-xhx9pzhj 1123 5 of of IN cord-005646-xhx9pzhj 1123 6 an an DT cord-005646-xhx9pzhj 1123 7 Life Life NNP cord-005646-xhx9pzhj 1123 8 Care Care NNP cord-005646-xhx9pzhj 1123 9 4 4 CD cord-005646-xhx9pzhj 1123 10 infusion infusion NN cord-005646-xhx9pzhj 1123 11 pump pump NN cord-005646-xhx9pzhj 1123 12 ( ( -LRB- cord-005646-xhx9pzhj 1123 13 ABBO'IT ABBO'IT NNP cord-005646-xhx9pzhj 1123 14 Lab Lab NNP cord-005646-xhx9pzhj 1123 15 . . . cord-005646-xhx9pzhj 1123 16 ) ) -RRB- cord-005646-xhx9pzhj 1123 17 with with IN cord-005646-xhx9pzhj 1123 18 its -PRON- PRP$ cord-005646-xhx9pzhj 1123 19 i.v i.v NNP cord-005646-xhx9pzhj 1123 20 . . NNP cord-005646-xhx9pzhj 1123 21 set set VBN cord-005646-xhx9pzhj 1123 22 for for IN cord-005646-xhx9pzhj 1123 23 maintenance maintenance NN cord-005646-xhx9pzhj 1123 24 intravenous intravenous JJ cord-005646-xhx9pzhj 1123 25 fluid fluid NN cord-005646-xhx9pzhj 1123 26 ( ( -LRB- cord-005646-xhx9pzhj 1123 27 flow flow VB cord-005646-xhx9pzhj 1123 28 < < XX cord-005646-xhx9pzhj 1123 29 6 6 CD cord-005646-xhx9pzhj 1123 30 mi mi NNP cord-005646-xhx9pzhj 1123 31 / / SYM cord-005646-xhx9pzhj 1123 32 h h NN cord-005646-xhx9pzhj 1123 33 ) ) -RRB- cord-005646-xhx9pzhj 1123 34 connected connect VBN cord-005646-xhx9pzhj 1123 35 to to IN cord-005646-xhx9pzhj 1123 36 a a DT cord-005646-xhx9pzhj 1123 37 3-way 3-way JJ cord-005646-xhx9pzhj 1123 38 stopcock stopcock NN cord-005646-xhx9pzhj 1123 39 . . . cord-005646-xhx9pzhj 1124 1 An an DT cord-005646-xhx9pzhj 1124 2 1 1 CD cord-005646-xhx9pzhj 1124 3 meter meter NN cord-005646-xhx9pzhj 1124 4 extension extension NN cord-005646-xhx9pzhj 1124 5 tubing tubing NN cord-005646-xhx9pzhj 1124 6 ( ( -LRB- cord-005646-xhx9pzhj 1124 7 VYGON VYGON NNP cord-005646-xhx9pzhj 1124 8 Lab Lab NNP cord-005646-xhx9pzhj 1124 9 . . . cord-005646-xhx9pzhj 1124 10 ) ) -RRB- cord-005646-xhx9pzhj 1124 11 was be VBD cord-005646-xhx9pzhj 1124 12 placed place VBN cord-005646-xhx9pzhj 1124 13 between between IN cord-005646-xhx9pzhj 1124 14 the the DT cord-005646-xhx9pzhj 1124 15 stopcock stopcock NN cord-005646-xhx9pzhj 1124 16 and and CC cord-005646-xhx9pzhj 1124 17 a a DT cord-005646-xhx9pzhj 1124 18 neonatal neonatal JJ cord-005646-xhx9pzhj 1124 19 catheter catheter NN cord-005646-xhx9pzhj 1124 20 , , . cord-005646-xhx9pzhj 1125 1 An an DT cord-005646-xhx9pzhj 1125 2 another another DT cord-005646-xhx9pzhj 1125 3 1 1 CD cord-005646-xhx9pzhj 1125 4 meter meter NN cord-005646-xhx9pzhj 1125 5 tubing tubing NN cord-005646-xhx9pzhj 1125 6 ( ( -LRB- cord-005646-xhx9pzhj 1125 7 injection injection NN cord-005646-xhx9pzhj 1125 8 tubing tubing NN cord-005646-xhx9pzhj 1125 9 ) ) -RRB- cord-005646-xhx9pzhj 1125 10 was be VBD cord-005646-xhx9pzhj 1125 11 connected connect VBN cord-005646-xhx9pzhj 1125 12 to to IN cord-005646-xhx9pzhj 1125 13 the the DT cord-005646-xhx9pzhj 1125 14 stopcock stopcock NN cord-005646-xhx9pzhj 1125 15 . . . cord-005646-xhx9pzhj 1126 1 The the DT cord-005646-xhx9pzhj 1126 2 volume volume NN cord-005646-xhx9pzhj 1126 3 of of IN cord-005646-xhx9pzhj 1126 4 the the DT cord-005646-xhx9pzhj 1126 5 injection injection NN cord-005646-xhx9pzhj 1126 6 circuit circuit NN cord-005646-xhx9pzhj 1126 7 was be VBD cord-005646-xhx9pzhj 1126 8 2.6 2.6 CD cord-005646-xhx9pzhj 1126 9 ml ml NNS cord-005646-xhx9pzhj 1126 10 . . . cord-005646-xhx9pzhj 1127 1 Simulations simulation NNS cord-005646-xhx9pzhj 1127 2 were be VBD cord-005646-xhx9pzhj 1127 3 realised realise VBN cord-005646-xhx9pzhj 1127 4 for for IN cord-005646-xhx9pzhj 1127 5 2 2 CD cord-005646-xhx9pzhj 1127 6 weights weight NNS cord-005646-xhx9pzhj 1127 7 ( ( -LRB- cord-005646-xhx9pzhj 1127 8 1 1 CD cord-005646-xhx9pzhj 1127 9 or or CC cord-005646-xhx9pzhj 1127 10 3 3 CD cord-005646-xhx9pzhj 1127 11 kg kg NNP cord-005646-xhx9pzhj 1127 12 ) ) -RRB- cord-005646-xhx9pzhj 1127 13 , , , cord-005646-xhx9pzhj 1127 14 with with IN cord-005646-xhx9pzhj 1127 15 a a DT cord-005646-xhx9pzhj 1127 16 doses dose NNS cord-005646-xhx9pzhj 1127 17 of of IN cord-005646-xhx9pzhj 1127 18 8 8 CD cord-005646-xhx9pzhj 1127 19 mg mg NNP cord-005646-xhx9pzhj 1127 20 / / SYM cord-005646-xhx9pzhj 1127 21 kg kg NNS cord-005646-xhx9pzhj 1127 22 and and CC cord-005646-xhx9pzhj 1127 23 a a DT cord-005646-xhx9pzhj 1127 24 injected inject VBN cord-005646-xhx9pzhj 1127 25 volume volume NN cord-005646-xhx9pzhj 1127 26 of of IN cord-005646-xhx9pzhj 1127 27 0,8 0,8 CD cord-005646-xhx9pzhj 1127 28 ml ml XX cord-005646-xhx9pzhj 1127 29 to to IN cord-005646-xhx9pzhj 1127 30 3 3 CD cord-005646-xhx9pzhj 1127 31 ml ml NN cord-005646-xhx9pzhj 1127 32 . . . cord-005646-xhx9pzhj 1128 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 1128 2 goal goal NN cord-005646-xhx9pzhj 1128 3 was be VBD cord-005646-xhx9pzhj 1128 4 to to TO cord-005646-xhx9pzhj 1128 5 perform perform VB cord-005646-xhx9pzhj 1128 6 a a DT cord-005646-xhx9pzhj 1128 7 complete complete JJ cord-005646-xhx9pzhj 1128 8 infusion infusion NN cord-005646-xhx9pzhj 1128 9 in in IN cord-005646-xhx9pzhj 1128 10 10 10 CD cord-005646-xhx9pzhj 1128 11 minutes minute NNS cord-005646-xhx9pzhj 1128 12 . . . cord-005646-xhx9pzhj 1129 1 We -PRON- PRP cord-005646-xhx9pzhj 1129 2 compare compare VBP cord-005646-xhx9pzhj 1129 3 one one CD cord-005646-xhx9pzhj 1129 4 method method NN cord-005646-xhx9pzhj 1129 5 of of IN cord-005646-xhx9pzhj 1129 6 infusion infusion NN cord-005646-xhx9pzhj 1129 7 with with IN cord-005646-xhx9pzhj 1129 8 an an DT cord-005646-xhx9pzhj 1129 9 electrical electrical JJ cord-005646-xhx9pzhj 1129 10 syringe syringe NN cord-005646-xhx9pzhj 1129 11 - - HYPH cord-005646-xhx9pzhj 1129 12 pump pump NN cord-005646-xhx9pzhj 1129 13 with with IN cord-005646-xhx9pzhj 1129 14 2 2 CD cord-005646-xhx9pzhj 1129 15 manual manual JJ cord-005646-xhx9pzhj 1129 16 methods method NNS cord-005646-xhx9pzhj 1129 17 : : : cord-005646-xhx9pzhj 1130 1 A a DT cord-005646-xhx9pzhj 1130 2 : : : cord-005646-xhx9pzhj 1131 1 Teico Teico NNP cord-005646-xhx9pzhj 1131 2 was be VBD cord-005646-xhx9pzhj 1131 3 infused infuse VBN cord-005646-xhx9pzhj 1131 4 with with IN cord-005646-xhx9pzhj 1131 5 a a DT cord-005646-xhx9pzhj 1131 6 syringe syringe NN cord-005646-xhx9pzhj 1131 7 - - HYPH cord-005646-xhx9pzhj 1131 8 pump pump NN cord-005646-xhx9pzhj 1131 9 Pilot Pilot NNP cord-005646-xhx9pzhj 1131 10 C C NNP cord-005646-xhx9pzhj 1131 11 ( ( -LRB- cord-005646-xhx9pzhj 1131 12 Becton Becton NNP cord-005646-xhx9pzhj 1131 13 & & CC cord-005646-xhx9pzhj 1131 14 Dickinson Dickinson NNP cord-005646-xhx9pzhj 1131 15 Lab Lab NNP cord-005646-xhx9pzhj 1131 16 . . . cord-005646-xhx9pzhj 1131 17 ) ) -RRB- cord-005646-xhx9pzhj 1132 1 according accord VBG cord-005646-xhx9pzhj 1132 2 to to IN cord-005646-xhx9pzhj 1132 3 a a DT cord-005646-xhx9pzhj 1132 4 protocol protocol NN cord-005646-xhx9pzhj 1132 5 using use VBG cord-005646-xhx9pzhj 1132 6 1 1 CD cord-005646-xhx9pzhj 1132 7 ) ) -RRB- cord-005646-xhx9pzhj 1132 8 a a DT cord-005646-xhx9pzhj 1132 9 priming priming NN cord-005646-xhx9pzhj 1132 10 before before IN cord-005646-xhx9pzhj 1132 11 connecting connect VBG cord-005646-xhx9pzhj 1132 12 the the DT cord-005646-xhx9pzhj 1132 13 syringe syringe NN cord-005646-xhx9pzhj 1132 14 to to IN cord-005646-xhx9pzhj 1132 15 the the DT cord-005646-xhx9pzhj 1132 16 tubing tubing NN cord-005646-xhx9pzhj 1132 17 ( ( -LRB- cord-005646-xhx9pzhj 1132 18 for for IN cord-005646-xhx9pzhj 1132 19 immediate immediate JJ cord-005646-xhx9pzhj 1132 20 starting starting NN cord-005646-xhx9pzhj 1132 21 of of IN cord-005646-xhx9pzhj 1132 22 infusion infusion NN cord-005646-xhx9pzhj 1132 23 ) ) -RRB- cord-005646-xhx9pzhj 1132 24 , , , cord-005646-xhx9pzhj 1132 25 2 2 LS cord-005646-xhx9pzhj 1132 26 ) ) -RRB- cord-005646-xhx9pzhj 1132 27 a a DT cord-005646-xhx9pzhj 1132 28 programmed program VBN cord-005646-xhx9pzhj 1132 29 volume volume NN cord-005646-xhx9pzhj 1132 30 injected inject VBN cord-005646-xhx9pzhj 1132 31 in in IN cord-005646-xhx9pzhj 1132 32 5 5 CD cord-005646-xhx9pzhj 1132 33 minutes minute NNS cord-005646-xhx9pzhj 1132 34 ( ( -LRB- cord-005646-xhx9pzhj 1132 35 the the DT cord-005646-xhx9pzhj 1132 36 drug drug NN cord-005646-xhx9pzhj 1132 37 volume volume NN cord-005646-xhx9pzhj 1132 38 was be VBD cord-005646-xhx9pzhj 1132 39 greater great JJR cord-005646-xhx9pzhj 1132 40 than than IN cord-005646-xhx9pzhj 1132 41 the the DT cord-005646-xhx9pzhj 1132 42 dose dose NN cord-005646-xhx9pzhj 1132 43 prescribed prescribe VBN cord-005646-xhx9pzhj 1132 44 to to TO cord-005646-xhx9pzhj 1132 45 avoid avoid VB cord-005646-xhx9pzhj 1132 46 loss loss NN cord-005646-xhx9pzhj 1132 47 of of IN cord-005646-xhx9pzhj 1132 48 Teico Teico NNP cord-005646-xhx9pzhj 1132 49 into into IN cord-005646-xhx9pzhj 1132 50 the the DT cord-005646-xhx9pzhj 1132 51 syringe syringe NN cord-005646-xhx9pzhj 1132 52 ) ) -RRB- cord-005646-xhx9pzhj 1132 53 , , , cord-005646-xhx9pzhj 1132 54 3 3 CD cord-005646-xhx9pzhj 1132 55 ) ) -RRB- cord-005646-xhx9pzhj 1132 56 a a DT cord-005646-xhx9pzhj 1132 57 5 5 CD cord-005646-xhx9pzhj 1132 58 ml ml NN cord-005646-xhx9pzhj 1132 59 wash wash NN cord-005646-xhx9pzhj 1132 60 out out RP cord-005646-xhx9pzhj 1132 61 was be VBD cord-005646-xhx9pzhj 1132 62 performed perform VBN cord-005646-xhx9pzhj 1132 63 over over IN cord-005646-xhx9pzhj 1132 64 5 5 CD cord-005646-xhx9pzhj 1132 65 minutes minute NNS cord-005646-xhx9pzhj 1132 66 with with IN cord-005646-xhx9pzhj 1132 67 the the DT cord-005646-xhx9pzhj 1132 68 syringe syringe NN cord-005646-xhx9pzhj 1132 69 pump pump NN cord-005646-xhx9pzhj 1132 70 . . . cord-005646-xhx9pzhj 1133 1 B b NN cord-005646-xhx9pzhj 1133 2 : : : cord-005646-xhx9pzhj 1134 1 Teico Teico NNP cord-005646-xhx9pzhj 1134 2 was be VBD cord-005646-xhx9pzhj 1134 3 manually manually RB cord-005646-xhx9pzhj 1134 4 injected inject VBN cord-005646-xhx9pzhj 1134 5 in in IN cord-005646-xhx9pzhj 1134 6 a a DT cord-005646-xhx9pzhj 1134 7 few few JJ cord-005646-xhx9pzhj 1134 8 seconds second NNS cord-005646-xhx9pzhj 1134 9 in in IN cord-005646-xhx9pzhj 1134 10 the the DT cord-005646-xhx9pzhj 1134 11 tubing tubing NN cord-005646-xhx9pzhj 1134 12 followed follow VBN cord-005646-xhx9pzhj 1134 13 by by IN cord-005646-xhx9pzhj 1134 14 a a DT cord-005646-xhx9pzhj 1134 15 5 5 CD cord-005646-xhx9pzhj 1134 16 ml ml NN cord-005646-xhx9pzhj 1134 17 wash wash VB cord-005646-xhx9pzhj 1134 18 out out RP cord-005646-xhx9pzhj 1134 19 over over IN cord-005646-xhx9pzhj 1134 20 10 10 CD cord-005646-xhx9pzhj 1134 21 minutes minute NNS cord-005646-xhx9pzhj 1134 22 . . . cord-005646-xhx9pzhj 1135 1 C C NNP cord-005646-xhx9pzhj 1135 2 : : : cord-005646-xhx9pzhj 1135 3 idem idem NN cord-005646-xhx9pzhj 1135 4 as as IN cord-005646-xhx9pzhj 1135 5 B b NN cord-005646-xhx9pzhj 1135 6 but but CC cord-005646-xhx9pzhj 1135 7 a a DT cord-005646-xhx9pzhj 1135 8 Nu Nu NNP cord-005646-xhx9pzhj 1135 9 Site site NN cord-005646-xhx9pzhj 1135 10 valve valve NN cord-005646-xhx9pzhj 1135 11 ( ( -LRB- cord-005646-xhx9pzhj 1135 12 Medex Medex NNP cord-005646-xhx9pzhj 1135 13 ) ) -RRB- cord-005646-xhx9pzhj 1135 14 was be VBD cord-005646-xhx9pzhj 1135 15 connected connect VBN cord-005646-xhx9pzhj 1135 16 to to IN cord-005646-xhx9pzhj 1135 17 the the DT cord-005646-xhx9pzhj 1135 18 proximal proximal JJ cord-005646-xhx9pzhj 1135 19 end end NN cord-005646-xhx9pzhj 1135 20 of of IN cord-005646-xhx9pzhj 1135 21 injection injection NN cord-005646-xhx9pzhj 1135 22 tubing tubing NN cord-005646-xhx9pzhj 1135 23 to to TO cord-005646-xhx9pzhj 1135 24 avoid avoid VB cord-005646-xhx9pzhj 1135 25 leakage leakage NN cord-005646-xhx9pzhj 1135 26 between between IN cord-005646-xhx9pzhj 1135 27 removal removal NN cord-005646-xhx9pzhj 1135 28 of of IN cord-005646-xhx9pzhj 1135 29 the the DT cord-005646-xhx9pzhj 1135 30 Teico Teico NNP cord-005646-xhx9pzhj 1135 31 syringe syringe NN cord-005646-xhx9pzhj 1135 32 and and CC cord-005646-xhx9pzhj 1135 33 connection connection NN cord-005646-xhx9pzhj 1135 34 of of IN cord-005646-xhx9pzhj 1135 35 the the DT cord-005646-xhx9pzhj 1135 36 wash wash NN cord-005646-xhx9pzhj 1135 37 out out RP cord-005646-xhx9pzhj 1135 38 syringe syringe NN cord-005646-xhx9pzhj 1135 39 . . . cord-005646-xhx9pzhj 1136 1 During during IN cord-005646-xhx9pzhj 1136 2 each each DT cord-005646-xhx9pzhj 1136 3 run run NN cord-005646-xhx9pzhj 1136 4 , , , cord-005646-xhx9pzhj 1136 5 serial serial JJ cord-005646-xhx9pzhj 1136 6 samples sample NNS cord-005646-xhx9pzhj 1136 7 were be VBD cord-005646-xhx9pzhj 1136 8 collected collect VBN cord-005646-xhx9pzhj 1136 9 every every DT cord-005646-xhx9pzhj 1136 10 ten ten CD cord-005646-xhx9pzhj 1136 11 minutes minute NNS cord-005646-xhx9pzhj 1136 12 over over IN cord-005646-xhx9pzhj 1136 13 a a DT cord-005646-xhx9pzhj 1136 14 one one CD cord-005646-xhx9pzhj 1136 15 hour hour NN cord-005646-xhx9pzhj 1136 16 period period NN cord-005646-xhx9pzhj 1136 17 . . . cord-005646-xhx9pzhj 1137 1 The the DT cord-005646-xhx9pzhj 1137 2 samples sample NNS cord-005646-xhx9pzhj 1137 3 were be VBD cord-005646-xhx9pzhj 1137 4 assessed assess VBN cord-005646-xhx9pzhj 1137 5 using use VBG cord-005646-xhx9pzhj 1137 6 HPLC HPLC NNP cord-005646-xhx9pzhj 1137 7 method method NN cord-005646-xhx9pzhj 1137 8 . . . cord-005646-xhx9pzhj 1138 1 Results result NNS cord-005646-xhx9pzhj 1138 2 : : : cord-005646-xhx9pzhj 1138 3 the the DT cord-005646-xhx9pzhj 1138 4 amount amount NN cord-005646-xhx9pzhj 1138 5 of of IN cord-005646-xhx9pzhj 1138 6 drug drug NN cord-005646-xhx9pzhj 1138 7 delivred delivre VBN cord-005646-xhx9pzhj 1138 8 at at IN cord-005646-xhx9pzhj 1138 9 10 10 CD cord-005646-xhx9pzhj 1138 10 minutes minute NNS cord-005646-xhx9pzhj 1138 11 was be VBD cord-005646-xhx9pzhj 1138 12 calculated calculate VBN cord-005646-xhx9pzhj 1138 13 and and CC cord-005646-xhx9pzhj 1138 14 expressed express VBN cord-005646-xhx9pzhj 1138 15 as as IN cord-005646-xhx9pzhj 1138 16 a a DT cord-005646-xhx9pzhj 1138 17 perventage perventage NN cord-005646-xhx9pzhj 1138 18 of of IN cord-005646-xhx9pzhj 1138 19 the the DT cord-005646-xhx9pzhj 1138 20 total total JJ cord-005646-xhx9pzhj 1138 21 amount amount NN cord-005646-xhx9pzhj 1138 22 of of IN cord-005646-xhx9pzhj 1138 23 Teico Teico NNP cord-005646-xhx9pzhj 1138 24 prescribed prescribe VBN cord-005646-xhx9pzhj 1138 25 . . . cord-005646-xhx9pzhj 1139 1 Results result NNS cord-005646-xhx9pzhj 1139 2 are be VBP cord-005646-xhx9pzhj 1139 3 a a DT cord-005646-xhx9pzhj 1139 4 mean mean NN cord-005646-xhx9pzhj 1139 5 of of IN cord-005646-xhx9pzhj 1139 6 5 5 CD cord-005646-xhx9pzhj 1139 7 to to TO cord-005646-xhx9pzhj 1139 8 8 8 CD cord-005646-xhx9pzhj 1139 9 rons ron NNS cord-005646-xhx9pzhj 1139 10 . . . cord-005646-xhx9pzhj 1140 1 A a DT cord-005646-xhx9pzhj 1140 2 B b NN cord-005646-xhx9pzhj 1140 3 C c NN cord-005646-xhx9pzhj 1140 4 1Kg 1kg NN cord-005646-xhx9pzhj 1140 5 94.2 94.2 CD cord-005646-xhx9pzhj 1140 6 + + CC cord-005646-xhx9pzhj 1141 1 17,9 17,9 CD cord-005646-xhx9pzhj 1141 2 % % NN cord-005646-xhx9pzhj 1142 1 86,8 86,8 LS cord-005646-xhx9pzhj 1142 2 + + CD cord-005646-xhx9pzhj 1142 3 9.1 9.1 CD cord-005646-xhx9pzhj 1142 4 % % NN cord-005646-xhx9pzhj 1142 5 94,4-+6.4 94,4-+6.4 CD cord-005646-xhx9pzhj 1142 6 % % NN cord-005646-xhx9pzhj 1143 1 3Kg 3kg JJ cord-005646-xhx9pzhj 1143 2 95-+4,9 95-+4,9 CD cord-005646-xhx9pzhj 1143 3 % % NN cord-005646-xhx9pzhj 1144 1 72-+13,4 72-+13,4 CD cord-005646-xhx9pzhj 1144 2 % % NN cord-005646-xhx9pzhj 1145 1 90.9-+6 90.9-+6 CD cord-005646-xhx9pzhj 1145 2 % % NN cord-005646-xhx9pzhj 1145 3 Conclusion conclusion NN cord-005646-xhx9pzhj 1145 4 : : : cord-005646-xhx9pzhj 1145 5 with with IN cord-005646-xhx9pzhj 1145 6 a a DT cord-005646-xhx9pzhj 1145 7 drug drug NN cord-005646-xhx9pzhj 1145 8 volume volume NN cord-005646-xhx9pzhj 1145 9 injected inject VBN cord-005646-xhx9pzhj 1145 10 < < NNP cord-005646-xhx9pzhj 1145 11 circuit circuit NNP cord-005646-xhx9pzhj 1145 12 volume volume NN cord-005646-xhx9pzhj 1145 13 and and CC cord-005646-xhx9pzhj 1145 14 a a DT cord-005646-xhx9pzhj 1145 15 valve valve NN cord-005646-xhx9pzhj 1145 16 , , . cord-005646-xhx9pzhj 1146 1 a a DT cord-005646-xhx9pzhj 1146 2 direct direct JJ cord-005646-xhx9pzhj 1146 3 i.v i.v NNP cord-005646-xhx9pzhj 1146 4 . . NNP cord-005646-xhx9pzhj 1146 5 administration administration NN cord-005646-xhx9pzhj 1146 6 of of IN cord-005646-xhx9pzhj 1146 7 the the DT cord-005646-xhx9pzhj 1146 8 drug drug NN cord-005646-xhx9pzhj 1146 9 in in IN cord-005646-xhx9pzhj 1146 10 the the DT cord-005646-xhx9pzhj 1146 11 circuit circuit NN cord-005646-xhx9pzhj 1146 12 followed follow VBN cord-005646-xhx9pzhj 1146 13 by by IN cord-005646-xhx9pzhj 1146 14 a a DT cord-005646-xhx9pzhj 1146 15 wash wash NN cord-005646-xhx9pzhj 1146 16 out out RP cord-005646-xhx9pzhj 1146 17 seems seem VBZ cord-005646-xhx9pzhj 1146 18 an an DT cord-005646-xhx9pzhj 1146 19 accurate accurate JJ cord-005646-xhx9pzhj 1146 20 alternative alternative NN cord-005646-xhx9pzhj 1146 21 to to IN cord-005646-xhx9pzhj 1146 22 drug drug NN cord-005646-xhx9pzhj 1146 23 infusion infusion NN cord-005646-xhx9pzhj 1146 24 conbroled conbrole VBN cord-005646-xhx9pzhj 1146 25 by by IN cord-005646-xhx9pzhj 1146 26 a a DT cord-005646-xhx9pzhj 1146 27 syringe syringe NN cord-005646-xhx9pzhj 1146 28 pump pump NN cord-005646-xhx9pzhj 1146 29 and and CC cord-005646-xhx9pzhj 1146 30 is be VBZ cord-005646-xhx9pzhj 1146 31 easier easy JJR cord-005646-xhx9pzhj 1146 32 to to TO cord-005646-xhx9pzhj 1146 33 perform perform VB cord-005646-xhx9pzhj 1146 34 . . . cord-005646-xhx9pzhj 1147 1 Doxapram Doxapram NNP cord-005646-xhx9pzhj 1147 2 hydrochloride hydrochloride NN cord-005646-xhx9pzhj 1147 3 is be VBZ cord-005646-xhx9pzhj 1147 4 a a DT cord-005646-xhx9pzhj 1147 5 central central JJ cord-005646-xhx9pzhj 1147 6 and and CC cord-005646-xhx9pzhj 1147 7 respiratory respiratory JJ cord-005646-xhx9pzhj 1147 8 stimulant stimulant NN cord-005646-xhx9pzhj 1147 9 which which WDT cord-005646-xhx9pzhj 1147 10 is be VBZ cord-005646-xhx9pzhj 1147 11 used use VBN cord-005646-xhx9pzhj 1147 12 in in IN cord-005646-xhx9pzhj 1147 13 neonatal neonatal JJ cord-005646-xhx9pzhj 1147 14 intensive intensive JJ cord-005646-xhx9pzhj 1147 15 care care NN cord-005646-xhx9pzhj 1147 16 units unit NNS cord-005646-xhx9pzhj 1147 17 to to TO cord-005646-xhx9pzhj 1147 18 treat treat VB cord-005646-xhx9pzhj 1147 19 caffeine caffeine NN cord-005646-xhx9pzhj 1147 20 - - HYPH cord-005646-xhx9pzhj 1147 21 resistant resistant JJ cord-005646-xhx9pzhj 1147 22 apnoes apnoe NNS cord-005646-xhx9pzhj 1147 23 of of IN cord-005646-xhx9pzhj 1147 24 the the DT cord-005646-xhx9pzhj 1147 25 newborn newborn NN cord-005646-xhx9pzhj 1147 26 . . . cord-005646-xhx9pzhj 1148 1 Routinely routinely RB cord-005646-xhx9pzhj 1148 2 , , , cord-005646-xhx9pzhj 1148 3 doxapram doxapram NNP cord-005646-xhx9pzhj 1148 4 is be VBZ cord-005646-xhx9pzhj 1148 5 administered administer VBN cord-005646-xhx9pzhj 1148 6 intravenously intravenously RB cord-005646-xhx9pzhj 1148 7 . . . cord-005646-xhx9pzhj 1149 1 Oral oral JJ cord-005646-xhx9pzhj 1149 2 administration administration NN cord-005646-xhx9pzhj 1149 3 would would MD cord-005646-xhx9pzhj 1149 4 be be VB cord-005646-xhx9pzhj 1149 5 much much RB cord-005646-xhx9pzhj 1149 6 easier easy JJR cord-005646-xhx9pzhj 1149 7 but but CC cord-005646-xhx9pzhj 1149 8 data datum NNS cord-005646-xhx9pzhj 1149 9 on on IN cord-005646-xhx9pzhj 1149 10 bioavailability bioavailability NN cord-005646-xhx9pzhj 1149 11 after after IN cord-005646-xhx9pzhj 1149 12 oral oral JJ cord-005646-xhx9pzhj 1149 13 administration administration NN cord-005646-xhx9pzhj 1149 14 are be VBP cord-005646-xhx9pzhj 1149 15 limited limit VBN cord-005646-xhx9pzhj 1149 16 ( ( -LRB- cord-005646-xhx9pzhj 1149 17 two two CD cord-005646-xhx9pzhj 1149 18 studies study NNS cord-005646-xhx9pzhj 1149 19 ) ) -RRB- cord-005646-xhx9pzhj 1149 20 and and CC cord-005646-xhx9pzhj 1149 21 show show VBP cord-005646-xhx9pzhj 1149 22 a a DT cord-005646-xhx9pzhj 1149 23 large large JJ cord-005646-xhx9pzhj 1149 24 variation variation NN cord-005646-xhx9pzhj 1149 25 . . . cord-005646-xhx9pzhj 1150 1 We -PRON- PRP cord-005646-xhx9pzhj 1150 2 therefore therefore RB cord-005646-xhx9pzhj 1150 3 studied study VBD cord-005646-xhx9pzhj 1150 4 the the DT cord-005646-xhx9pzhj 1150 5 oral oral JJ cord-005646-xhx9pzhj 1150 6 bioavailability bioavailability NN cord-005646-xhx9pzhj 1150 7 of of IN cord-005646-xhx9pzhj 1150 8 doxapram doxapram NNP cord-005646-xhx9pzhj 1150 9 in in IN cord-005646-xhx9pzhj 1150 10 8 8 CD cord-005646-xhx9pzhj 1150 11 preterm preterm JJ cord-005646-xhx9pzhj 1150 12 infants infant NNS cord-005646-xhx9pzhj 1150 13 . . . cord-005646-xhx9pzhj 1151 1 Doxapram Doxapram NNP cord-005646-xhx9pzhj 1151 2 treatment treatment NN cord-005646-xhx9pzhj 1151 3 was be VBD cord-005646-xhx9pzhj 1151 4 started start VBN cord-005646-xhx9pzhj 1151 5 with with IN cord-005646-xhx9pzhj 1151 6 an an DT cord-005646-xhx9pzhj 1151 7 intravenous intravenous JJ cord-005646-xhx9pzhj 1151 8 loading loading NN cord-005646-xhx9pzhj 1151 9 dose dose NN cord-005646-xhx9pzhj 1151 10 of of IN cord-005646-xhx9pzhj 1151 11 2,5 2,5 CD cord-005646-xhx9pzhj 1151 12 mg mg NNP cord-005646-xhx9pzhj 1151 13 / / SYM cord-005646-xhx9pzhj 1151 14 kg kg NNS cord-005646-xhx9pzhj 1151 15 during during IN cord-005646-xhx9pzhj 1151 16 15 15 CD cord-005646-xhx9pzhj 1151 17 minutes minute NNS cord-005646-xhx9pzhj 1151 18 , , , cord-005646-xhx9pzhj 1151 19 followed follow VBN cord-005646-xhx9pzhj 1151 20 by by IN cord-005646-xhx9pzhj 1151 21 a a DT cord-005646-xhx9pzhj 1151 22 continuous continuous JJ cord-005646-xhx9pzhj 1151 23 infusion infusion NN cord-005646-xhx9pzhj 1151 24 of of IN cord-005646-xhx9pzhj 1151 25 1 1 CD cord-005646-xhx9pzhj 1151 26 mg mg NNP cord-005646-xhx9pzhj 1151 27 / / SYM cord-005646-xhx9pzhj 1151 28 kg kg NNP cord-005646-xhx9pzhj 1151 29 / / SYM cord-005646-xhx9pzhj 1151 30 h h NN cord-005646-xhx9pzhj 1151 31 . . . cord-005646-xhx9pzhj 1152 1 After after IN cord-005646-xhx9pzhj 1152 2 24 24 CD cord-005646-xhx9pzhj 1152 3 h h NN cord-005646-xhx9pzhj 1152 4 the the DT cord-005646-xhx9pzhj 1152 5 intravenous intravenous JJ cord-005646-xhx9pzhj 1152 6 administration administration NN cord-005646-xhx9pzhj 1152 7 was be VBD cord-005646-xhx9pzhj 1152 8 changed change VBN cord-005646-xhx9pzhj 1152 9 to to IN cord-005646-xhx9pzhj 1152 10 continuous continuous JJ cord-005646-xhx9pzhj 1152 11 oral oral JJ cord-005646-xhx9pzhj 1152 12 administration administration NN cord-005646-xhx9pzhj 1152 13 with with IN cord-005646-xhx9pzhj 1152 14 the the DT cord-005646-xhx9pzhj 1152 15 same same JJ cord-005646-xhx9pzhj 1152 16 dosage dosage NN cord-005646-xhx9pzhj 1152 17 , , , cord-005646-xhx9pzhj 1152 18 Blood blood NN cord-005646-xhx9pzhj 1152 19 samples sample NNS cord-005646-xhx9pzhj 1152 20 were be VBD cord-005646-xhx9pzhj 1152 21 collected collect VBN cord-005646-xhx9pzhj 1152 22 24 24 CD cord-005646-xhx9pzhj 1152 23 h h NN cord-005646-xhx9pzhj 1152 24 after after IN cord-005646-xhx9pzhj 1152 25 both both CC cord-005646-xhx9pzhj 1152 26 the the DT cord-005646-xhx9pzhj 1152 27 intravenous intravenous JJ cord-005646-xhx9pzhj 1152 28 and and CC cord-005646-xhx9pzhj 1152 29 oral oral JJ cord-005646-xhx9pzhj 1152 30 administration administration NN cord-005646-xhx9pzhj 1152 31 and and CC cord-005646-xhx9pzhj 1152 32 analyzed analyze VBN cord-005646-xhx9pzhj 1152 33 by by IN cord-005646-xhx9pzhj 1152 34 HPLC HPLC NNP cord-005646-xhx9pzhj 1152 35 - - HYPH cord-005646-xhx9pzhj 1152 36 assay assay NN cord-005646-xhx9pzhj 1152 37 . . . cord-005646-xhx9pzhj 1153 1 Apnoea Apnoea NNP cord-005646-xhx9pzhj 1153 2 rates rate NNS cord-005646-xhx9pzhj 1153 3 per per IN cord-005646-xhx9pzhj 1153 4 6 6 CD cord-005646-xhx9pzhj 1153 5 hours hour NNS cord-005646-xhx9pzhj 1153 6 were be VBD cord-005646-xhx9pzhj 1153 7 listed list VBN cord-005646-xhx9pzhj 1153 8 before before IN cord-005646-xhx9pzhj 1153 9 and and CC cord-005646-xhx9pzhj 1153 10 after after IN cord-005646-xhx9pzhj 1153 11 starting start VBG cord-005646-xhx9pzhj 1153 12 doxapram doxapram NNP cord-005646-xhx9pzhj 1153 13 treatment treatment NN cord-005646-xhx9pzhj 1153 14 . . . cord-005646-xhx9pzhj 1154 1 The the DT cord-005646-xhx9pzhj 1154 2 median median JJ cord-005646-xhx9pzhj 1154 3 apnoea apnoea NN cord-005646-xhx9pzhj 1154 4 rate rate NN cord-005646-xhx9pzhj 1154 5 per per IN cord-005646-xhx9pzhj 1154 6 6 6 CD cord-005646-xhx9pzhj 1154 7 hours hour NNS cord-005646-xhx9pzhj 1154 8 declined decline VBD cord-005646-xhx9pzhj 1154 9 from from IN cord-005646-xhx9pzhj 1154 10 9 9 CD cord-005646-xhx9pzhj 1154 11 to to IN cord-005646-xhx9pzhj 1154 12 2 2 CD cord-005646-xhx9pzhj 1154 13 after after IN cord-005646-xhx9pzhj 1154 14 both both CC cord-005646-xhx9pzhj 1154 15 the the DT cord-005646-xhx9pzhj 1154 16 intravenous intravenous JJ cord-005646-xhx9pzhj 1154 17 and and CC cord-005646-xhx9pzhj 1154 18 oral oral JJ cord-005646-xhx9pzhj 1154 19 administration administration NN cord-005646-xhx9pzhj 1154 20 . . . cord-005646-xhx9pzhj 1155 1 The the DT cord-005646-xhx9pzhj 1155 2 oral oral JJ cord-005646-xhx9pzhj 1155 3 bioavailability bioavailability NN cord-005646-xhx9pzhj 1155 4 of of IN cord-005646-xhx9pzhj 1155 5 doxapram doxapram NNP cord-005646-xhx9pzhj 1155 6 is be VBZ cord-005646-xhx9pzhj 1155 7 between between IN cord-005646-xhx9pzhj 1155 8 43 43 CD cord-005646-xhx9pzhj 1155 9 and and CC cord-005646-xhx9pzhj 1155 10 65 65 CD cord-005646-xhx9pzhj 1155 11 % % NN cord-005646-xhx9pzhj 1155 12 , , , cord-005646-xhx9pzhj 1155 13 indicating indicate VBG cord-005646-xhx9pzhj 1155 14 that that IN cord-005646-xhx9pzhj 1155 15 the the DT cord-005646-xhx9pzhj 1155 16 oral oral JJ cord-005646-xhx9pzhj 1155 17 route route NN cord-005646-xhx9pzhj 1155 18 can can MD cord-005646-xhx9pzhj 1155 19 be be VB cord-005646-xhx9pzhj 1155 20 used use VBN cord-005646-xhx9pzhj 1155 21 effectively effectively RB cord-005646-xhx9pzhj 1155 22 in in IN cord-005646-xhx9pzhj 1155 23 these these DT cord-005646-xhx9pzhj 1155 24 infants infant NNS cord-005646-xhx9pzhj 1155 25 2 2 CD cord-005646-xhx9pzhj 1155 26 . . . cord-005646-xhx9pzhj 1156 1 There there EX cord-005646-xhx9pzhj 1156 2 were be VBD cord-005646-xhx9pzhj 1156 3 no no DT cord-005646-xhx9pzhj 1156 4 differences difference NNS cord-005646-xhx9pzhj 1156 5 in in IN cord-005646-xhx9pzhj 1156 6 the the DT cord-005646-xhx9pzhj 1156 7 decline decline NN cord-005646-xhx9pzhj 1156 8 of of IN cord-005646-xhx9pzhj 1156 9 the the DT cord-005646-xhx9pzhj 1156 10 apnoea apnoea NN cord-005646-xhx9pzhj 1156 11 rate rate NN cord-005646-xhx9pzhj 1156 12 after after IN cord-005646-xhx9pzhj 1156 13 intravenous intravenous JJ cord-005646-xhx9pzhj 1156 14 versus versus IN cord-005646-xhx9pzhj 1156 15 oral oral JJ cord-005646-xhx9pzhj 1156 16 administration administration NN cord-005646-xhx9pzhj 1156 17 of of IN cord-005646-xhx9pzhj 1156 18 doxapram doxapram NNP cord-005646-xhx9pzhj 1156 19 , , , cord-005646-xhx9pzhj 1156 20 Infasurf Infasurf NNP cord-005646-xhx9pzhj 1156 21 R R NNP cord-005646-xhx9pzhj 1156 22 has have VBZ cord-005646-xhx9pzhj 1156 23 been be VBN cord-005646-xhx9pzhj 1156 24 comnared comnare VBN cord-005646-xhx9pzhj 1156 25 with with IN cord-005646-xhx9pzhj 1156 26 Exosurf Exosurf NNP cord-005646-xhx9pzhj 1156 27 R R NNP cord-005646-xhx9pzhj 1156 28 in in IN cord-005646-xhx9pzhj 1156 29 two two CD cord-005646-xhx9pzhj 1156 30 studies study NNS cord-005646-xhx9pzhj 1156 31 : : : cord-005646-xhx9pzhj 1156 32 one one CD cord-005646-xhx9pzhj 1156 33 as as IN cord-005646-xhx9pzhj 1156 34 DroDhvlaxis DroDhvlaxis NNPS cord-005646-xhx9pzhj 1156 35 and and CC cord-005646-xhx9pzhj 1156 36 the the DT cord-005646-xhx9pzhj 1156 37 other other JJ cord-005646-xhx9pzhj 1156 38 a a DT cord-005646-xhx9pzhj 1156 39 rescue rescue NN cord-005646-xhx9pzhj 1156 40 trial trial NN cord-005646-xhx9pzhj 1156 41 . . . cord-005646-xhx9pzhj 1157 1 Similar similar JJ cord-005646-xhx9pzhj 1157 2 . . . cord-005646-xhx9pzhj 1158 1 althouah althouah NNP cord-005646-xhx9pzhj 1158 2 non non JJ cord-005646-xhx9pzhj 1158 3 - - JJ cord-005646-xhx9pzhj 1158 4 sianificant sianificant JJ cord-005646-xhx9pzhj 1158 5 benefits benefit NNS cord-005646-xhx9pzhj 1158 6 were be VBD cord-005646-xhx9pzhj 1158 7 found find VBN cord-005646-xhx9pzhj 1158 8 for for IN cord-005646-xhx9pzhj 1158 9 the the DT cord-005646-xhx9pzhj 1158 10 natural natural JJ cord-005646-xhx9pzhj 1158 11 surfactant surfactant NN cord-005646-xhx9pzhj 1158 12 . . . cord-005646-xhx9pzhj 1159 1 In in IN cord-005646-xhx9pzhj 1159 2 6 6 CD cord-005646-xhx9pzhj 1159 3 trials trial NNS cord-005646-xhx9pzhj 1159 4 there there EX cord-005646-xhx9pzhj 1159 5 was be VBD cord-005646-xhx9pzhj 1159 6 a a DT cord-005646-xhx9pzhj 1159 7 sianificant sianificant JJ cord-005646-xhx9pzhj 1159 8 reduction reduction NN cord-005646-xhx9pzhj 1159 9 in in IN cord-005646-xhx9pzhj 1159 10 Dulmonarv Dulmonarv NNP cord-005646-xhx9pzhj 1159 11 air air NN cord-005646-xhx9pzhj 1159 12 leaks leak NNS cord-005646-xhx9pzhj 1159 13 fOR for IN cord-005646-xhx9pzhj 1159 14 0.53 0.53 CD cord-005646-xhx9pzhj 1159 15 : : : cord-005646-xhx9pzhj 1159 16 95 95 CD cord-005646-xhx9pzhj 1159 17 % % NN cord-005646-xhx9pzhj 1159 18 CI CI NNP cord-005646-xhx9pzhj 1159 19 00.41 00.41 CD cord-005646-xhx9pzhj 1159 20 - - HYPH cord-005646-xhx9pzhj 1159 21 0.641 0.641 CD cord-005646-xhx9pzhj 1159 22 for for IN cord-005646-xhx9pzhj 1159 23 babies baby NNS cord-005646-xhx9pzhj 1159 24 treated treat VBN cord-005646-xhx9pzhj 1159 25 with with IN cord-005646-xhx9pzhj 1159 26 natural natural JJ cord-005646-xhx9pzhj 1159 27 comnared comnared JJ cord-005646-xhx9pzhj 1159 28 to to IN cord-005646-xhx9pzhj 1159 29 svnthetic svnthetic JJ cord-005646-xhx9pzhj 1159 30 surfactants surfactant NNS cord-005646-xhx9pzhj 1159 31 . . . cord-005646-xhx9pzhj 1160 1 For for IN cord-005646-xhx9pzhj 1160 2 7 7 CD cord-005646-xhx9pzhj 1160 3 trials trial NNS cord-005646-xhx9pzhj 1160 4 ( ( -LRB- cord-005646-xhx9pzhj 1160 5 3554 3554 CD cord-005646-xhx9pzhj 1160 6 babies~ babies~ NNP cord-005646-xhx9pzhj 1160 7 comDarina comdarina VB cord-005646-xhx9pzhj 1160 8 natural natural JJ cord-005646-xhx9pzhj 1160 9 and and CC cord-005646-xhx9pzhj 1160 10 synthetic synthetic JJ cord-005646-xhx9pzhj 1160 11 surfactants surfactant NNS cord-005646-xhx9pzhj 1160 12 for for IN cord-005646-xhx9pzhj 1160 13 RDS RDS NNP cord-005646-xhx9pzhj 1160 14 { { -LRB- cord-005646-xhx9pzhj 1160 15 6 6 CD cord-005646-xhx9pzhj 1160 16 comDarina comdarina JJ cord-005646-xhx9pzhj 1160 17 Survanta Survanta NNP cord-005646-xhx9pzhj 1160 18 R R NNP cord-005646-xhx9pzhj 1160 19 and and CC cord-005646-xhx9pzhj 1160 20 Exosurf Exosurf NNP cord-005646-xhx9pzhj 1160 21 R. R. NNP cord-005646-xhx9pzhj 1160 22 and and CC cord-005646-xhx9pzhj 1160 23 one one CD cord-005646-xhx9pzhj 1160 24 Infasurf Infasurf NNP cord-005646-xhx9pzhj 1160 25 R R NNP cord-005646-xhx9pzhj 1160 26 and and CC cord-005646-xhx9pzhj 1160 27 ExesurfR% ExesurfR% NNP cord-005646-xhx9pzhj 1160 28 neonatal neonatal JJ cord-005646-xhx9pzhj 1160 29 mortalitv mortalitv NNP cord-005646-xhx9pzhj 1160 30 was be VBD cord-005646-xhx9pzhj 1160 31 sianificantlv sianificantlv NNP cord-005646-xhx9pzhj 1160 32 reduced reduce VBN cord-005646-xhx9pzhj 1160 33 ( ( -LRB- cord-005646-xhx9pzhj 1160 34 OR or JJ cord-005646-xhx9pzhj 1160 35 0.80 0.80 CD cord-005646-xhx9pzhj 1160 36 : : : cord-005646-xhx9pzhj 1160 37 95 95 CD cord-005646-xhx9pzhj 1160 38 % % NN cord-005646-xhx9pzhj 1160 39 CI CI NNP cord-005646-xhx9pzhj 1160 40 0.66 0.66 CD cord-005646-xhx9pzhj 1160 41 - - HYPH cord-005646-xhx9pzhj 1160 42 0.971 0.971 CD cord-005646-xhx9pzhj 1160 43 with with IN cord-005646-xhx9pzhj 1160 44 natural natural JJ cord-005646-xhx9pzhj 1160 45 compared compare VBN cord-005646-xhx9pzhj 1160 46 to to IN cord-005646-xhx9pzhj 1160 47 synthetic synthetic JJ cord-005646-xhx9pzhj 1160 48 surfactant surfactant NN cord-005646-xhx9pzhj 1160 49 treatment treatment NN cord-005646-xhx9pzhj 1160 50 . . . cord-005646-xhx9pzhj 1161 1 In in IN cord-005646-xhx9pzhj 1161 2 two two CD cord-005646-xhx9pzhj 1161 3 further further JJ cord-005646-xhx9pzhj 1161 4 trials trial NNS cord-005646-xhx9pzhj 1161 5 different different JJ cord-005646-xhx9pzhj 1161 6 natural natural JJ cord-005646-xhx9pzhj 1161 7 surfactant surfactant NN cord-005646-xhx9pzhj 1161 8 Drenarations Drenarations NNP cord-005646-xhx9pzhj 1161 9 were be VBD cord-005646-xhx9pzhj 1161 10 compared compare VBN cord-005646-xhx9pzhj 1161 11 . . . cord-005646-xhx9pzhj 1162 1 Reduced reduce VBN cord-005646-xhx9pzhj 1162 2 oxvaen oxvaen NN cord-005646-xhx9pzhj 1162 3 needs need VBZ cord-005646-xhx9pzhj 1162 4 for for IN cord-005646-xhx9pzhj 1162 5 24 24 CD cord-005646-xhx9pzhj 1162 6 hours hour NNS cord-005646-xhx9pzhj 1162 7 after after IN cord-005646-xhx9pzhj 1162 8 treatment treatment NN cord-005646-xhx9pzhj 1162 9 were be VBD cord-005646-xhx9pzhj 1162 10 found find VBN cord-005646-xhx9pzhj 1162 11 for for IN cord-005646-xhx9pzhj 1162 12 R r NN cord-005646-xhx9pzhj 1162 13 R r NN cord-005646-xhx9pzhj 1162 14 Infasurf Infasurf NNP cord-005646-xhx9pzhj 1162 15 and and CC cord-005646-xhx9pzhj 1162 16 Curosurf Curosurf NNP cord-005646-xhx9pzhj 1162 17 respectively respectively RB cord-005646-xhx9pzhj 1162 18 when when WRB cord-005646-xhx9pzhj 1162 19 each each DT cord-005646-xhx9pzhj 1162 20 was be VBD cord-005646-xhx9pzhj 1162 21 compared compare VBN cord-005646-xhx9pzhj 1162 22 to to IN cord-005646-xhx9pzhj 1162 23 Survanta Survanta NNP cord-005646-xhx9pzhj 1162 24 R. R. NNP cord-005646-xhx9pzhj 1162 25 AnDarent AnDarent NNP cord-005646-xhx9pzhj 1162 26 lonaer lonaer JJ cord-005646-xhx9pzhj 1162 27 - - HYPH cord-005646-xhx9pzhj 1162 28 term term NN cord-005646-xhx9pzhj 1162 29 benefits benefit NNS cord-005646-xhx9pzhj 1162 30 from from IN cord-005646-xhx9pzhj 1162 31 these these DT cord-005646-xhx9pzhj 1162 32 surfactants surfactant NNS cord-005646-xhx9pzhj 1162 33 were be VBD cord-005646-xhx9pzhj 1162 34 not not RB cord-005646-xhx9pzhj 1162 35 statisticallv statisticallv NN cord-005646-xhx9pzhj 1162 36 sianificant sianificant NN cord-005646-xhx9pzhj 1162 37 . . . cord-005646-xhx9pzhj 1163 1 Further further JJ cord-005646-xhx9pzhj 1163 2 trials trial NNS cord-005646-xhx9pzhj 1163 3 will will MD cord-005646-xhx9pzhj 1163 4 be be VB cord-005646-xhx9pzhj 1163 5 needed need VBN cord-005646-xhx9pzhj 1163 6 to to TO cord-005646-xhx9pzhj 1163 7 ascertain ascertain VB cord-005646-xhx9pzhj 1163 8 differences difference NNS cord-005646-xhx9pzhj 1163 9 between between IN cord-005646-xhx9pzhj 1163 10 various various JJ cord-005646-xhx9pzhj 1163 11 surfactant surfactant NN cord-005646-xhx9pzhj 1163 12 preparations preparation NNS cord-005646-xhx9pzhj 1163 13 . . . cord-005646-xhx9pzhj 1164 1 INTRODUCTION introduction JJ cord-005646-xhx9pzhj 1164 2 Bacterial bacterial JJ cord-005646-xhx9pzhj 1164 3 meningitis meningitis NN cord-005646-xhx9pzhj 1164 4 is be VBZ cord-005646-xhx9pzhj 1164 5 a a DT cord-005646-xhx9pzhj 1164 6 common common JJ cord-005646-xhx9pzhj 1164 7 cause cause NN cord-005646-xhx9pzhj 1164 8 of of IN cord-005646-xhx9pzhj 1164 9 admission admission NN cord-005646-xhx9pzhj 1164 10 in in IN cord-005646-xhx9pzhj 1164 11 the the DT cord-005646-xhx9pzhj 1164 12 paediatric paediatric JJ cord-005646-xhx9pzhj 1164 13 age age NN cord-005646-xhx9pzhj 1164 14 group group NN cord-005646-xhx9pzhj 1164 15 , , , cord-005646-xhx9pzhj 1164 16 and and CC cord-005646-xhx9pzhj 1164 17 one one NN cord-005646-xhx9pzhj 1164 18 which which WDT cord-005646-xhx9pzhj 1164 19 still still RB cord-005646-xhx9pzhj 1164 20 carries carry VBZ cord-005646-xhx9pzhj 1164 21 a a DT cord-005646-xhx9pzhj 1164 22 high high JJ cord-005646-xhx9pzhj 1164 23 morbidity morbidity NN cord-005646-xhx9pzhj 1164 24 and and CC cord-005646-xhx9pzhj 1164 25 mortality mortality NN cord-005646-xhx9pzhj 1164 26 . . . cord-005646-xhx9pzhj 1165 1 These these DT cord-005646-xhx9pzhj 1165 2 complications complication NNS cord-005646-xhx9pzhj 1165 3 are be VBP cord-005646-xhx9pzhj 1165 4 strongly strongly RB cord-005646-xhx9pzhj 1165 5 associated associate VBN cord-005646-xhx9pzhj 1165 6 with with IN cord-005646-xhx9pzhj 1165 7 a a DT cord-005646-xhx9pzhj 1165 8 delay delay NN cord-005646-xhx9pzhj 1165 9 in in IN cord-005646-xhx9pzhj 1165 10 antibacterial antibacterial JJ cord-005646-xhx9pzhj 1165 11 therapy therapy NN cord-005646-xhx9pzhj 1165 12 . . . cord-005646-xhx9pzhj 1166 1 A a DT cord-005646-xhx9pzhj 1166 2 significant significant JJ cord-005646-xhx9pzhj 1166 3 proportion proportion NN cord-005646-xhx9pzhj 1166 4 of of IN cord-005646-xhx9pzhj 1166 5 these these DT cord-005646-xhx9pzhj 1166 6 patients patient NNS cord-005646-xhx9pzhj 1166 7 require require VBP cord-005646-xhx9pzhj 1166 8 mechanical mechanical JJ cord-005646-xhx9pzhj 1166 9 ventilation ventilation NN cord-005646-xhx9pzhj 1166 10 ; ; : cord-005646-xhx9pzhj 1166 11 it -PRON- PRP cord-005646-xhx9pzhj 1166 12 is be VBZ cord-005646-xhx9pzhj 1166 13 in in IN cord-005646-xhx9pzhj 1166 14 this this DT cord-005646-xhx9pzhj 1166 15 particular particular JJ cord-005646-xhx9pzhj 1166 16 group group NN cord-005646-xhx9pzhj 1166 17 of of IN cord-005646-xhx9pzhj 1166 18 patients patient NNS cord-005646-xhx9pzhj 1166 19 that that IN cord-005646-xhx9pzhj 1166 20 survival survival NN cord-005646-xhx9pzhj 1166 21 is be VBZ cord-005646-xhx9pzhj 1166 22 greatly greatly RB cord-005646-xhx9pzhj 1166 23 diminished diminish VBN cord-005646-xhx9pzhj 1166 24 . . . cord-005646-xhx9pzhj 1167 1 The the DT cord-005646-xhx9pzhj 1167 2 identification identification NN cord-005646-xhx9pzhj 1167 3 of of IN cord-005646-xhx9pzhj 1167 4 risk risk NN cord-005646-xhx9pzhj 1167 5 factors factor NNS cord-005646-xhx9pzhj 1167 6 for for IN cord-005646-xhx9pzhj 1167 7 mechanical mechanical JJ cord-005646-xhx9pzhj 1167 8 ventilation ventilation NN cord-005646-xhx9pzhj 1167 9 associated associate VBN cord-005646-xhx9pzhj 1167 10 with with IN cord-005646-xhx9pzhj 1167 11 bacterial bacterial JJ cord-005646-xhx9pzhj 1167 12 meninges meninge NNS cord-005646-xhx9pzhj 1167 13 may may MD cord-005646-xhx9pzhj 1167 14 help help VB cord-005646-xhx9pzhj 1167 15 improving improve VBG cord-005646-xhx9pzhj 1167 16 survival survival NN cord-005646-xhx9pzhj 1167 17 by by IN cord-005646-xhx9pzhj 1167 18 shortening shorten VBG cord-005646-xhx9pzhj 1167 19 the the DT cord-005646-xhx9pzhj 1167 20 delay delay NN cord-005646-xhx9pzhj 1167 21 to to IN cord-005646-xhx9pzhj 1167 22 ICU ICU NNP cord-005646-xhx9pzhj 1167 23 referral referral NN cord-005646-xhx9pzhj 1167 24 . . . cord-005646-xhx9pzhj 1168 1 The the DT cord-005646-xhx9pzhj 1168 2 Paediatdc Paediatdc NNP cord-005646-xhx9pzhj 1168 3 Risk Risk NNP cord-005646-xhx9pzhj 1168 4 of of IN cord-005646-xhx9pzhj 1168 5 Mortality Mortality NNP cord-005646-xhx9pzhj 1168 6 Score Score NNP cord-005646-xhx9pzhj 1168 7 ( ( -LRB- cord-005646-xhx9pzhj 1168 8 PRISM PRISM NNP cord-005646-xhx9pzhj 1168 9 ) ) -RRB- cord-005646-xhx9pzhj 1168 10 is be VBZ cord-005646-xhx9pzhj 1168 11 the the DT cord-005646-xhx9pzhj 1168 12 most most RBS cord-005646-xhx9pzhj 1168 13 widely widely RB cord-005646-xhx9pzhj 1168 14 used use VBN cord-005646-xhx9pzhj 1168 15 scoring scoring NN cord-005646-xhx9pzhj 1168 16 system system NN cord-005646-xhx9pzhj 1168 17 in in IN cord-005646-xhx9pzhj 1168 18 the the DT cord-005646-xhx9pzhj 1168 19 paediatric paediatric JJ cord-005646-xhx9pzhj 1168 20 ICU ICU NNP cord-005646-xhx9pzhj 1168 21 literature literature NN cord-005646-xhx9pzhj 1168 22 ; ; : cord-005646-xhx9pzhj 1168 23 the the DT cord-005646-xhx9pzhj 1168 24 accuracy accuracy NN cord-005646-xhx9pzhj 1168 25 of of IN cord-005646-xhx9pzhj 1168 26 PRISM PRISM NNP cord-005646-xhx9pzhj 1168 27 on on IN cord-005646-xhx9pzhj 1168 28 predicting predict VBG cord-005646-xhx9pzhj 1168 29 outcome outcome NN cord-005646-xhx9pzhj 1168 30 in in IN cord-005646-xhx9pzhj 1168 31 meningitis meningitis NN cord-005646-xhx9pzhj 1168 32 has have VBZ cord-005646-xhx9pzhj 1168 33 been be VBN cord-005646-xhx9pzhj 1168 34 shown show VBN cord-005646-xhx9pzhj 1168 35 to to TO cord-005646-xhx9pzhj 1168 36 be be VB cord-005646-xhx9pzhj 1168 37 poor poor JJ cord-005646-xhx9pzhj 1168 38 . . . cord-005646-xhx9pzhj 1169 1 AIM aim VB cord-005646-xhx9pzhj 1169 2 We -PRON- PRP cord-005646-xhx9pzhj 1169 3 aimed aim VBD cord-005646-xhx9pzhj 1169 4 to to TO cord-005646-xhx9pzhj 1169 5 describe describe VB cord-005646-xhx9pzhj 1169 6 our -PRON- PRP$ cord-005646-xhx9pzhj 1169 7 population population NN cord-005646-xhx9pzhj 1169 8 of of IN cord-005646-xhx9pzhj 1169 9 patients patient NNS cord-005646-xhx9pzhj 1169 10 with with IN cord-005646-xhx9pzhj 1169 11 bacterial bacterial JJ cord-005646-xhx9pzhj 1169 12 meningitis meningitis NN cord-005646-xhx9pzhj 1169 13 requiring require VBG cord-005646-xhx9pzhj 1169 14 ventilation ventilation NN cord-005646-xhx9pzhj 1169 15 , , , cord-005646-xhx9pzhj 1169 16 and and CC cord-005646-xhx9pzhj 1169 17 then then RB cord-005646-xhx9pzhj 1169 18 to to TO cord-005646-xhx9pzhj 1169 19 identify identify VB cord-005646-xhx9pzhj 1169 20 predictors predictor NNS cord-005646-xhx9pzhj 1169 21 of of IN cord-005646-xhx9pzhj 1169 22 survival survival NN cord-005646-xhx9pzhj 1169 23 . . . cord-005646-xhx9pzhj 1170 1 METHODS methods NN cord-005646-xhx9pzhj 1171 1 This this DT cord-005646-xhx9pzhj 1171 2 study study NN cord-005646-xhx9pzhj 1171 3 was be VBD cord-005646-xhx9pzhj 1171 4 conducted conduct VBN cord-005646-xhx9pzhj 1171 5 at at IN cord-005646-xhx9pzhj 1171 6 the the DT cord-005646-xhx9pzhj 1171 7 Baragwanath Baragwanath NNP cord-005646-xhx9pzhj 1171 8 Hospital Hospital NNP cord-005646-xhx9pzhj 1171 9 in in IN cord-005646-xhx9pzhj 1171 10 South South NNP cord-005646-xhx9pzhj 1171 11 Africa Africa NNP cord-005646-xhx9pzhj 1171 12 which which WDT cord-005646-xhx9pzhj 1171 13 is be VBZ cord-005646-xhx9pzhj 1171 14 an an DT cord-005646-xhx9pzhj 1171 15 Universityaffiliated Universityaffiliated NNP cord-005646-xhx9pzhj 1171 16 institution institution NN cord-005646-xhx9pzhj 1171 17 with with IN cord-005646-xhx9pzhj 1171 18 end end NN cord-005646-xhx9pzhj 1171 19 average average JJ cord-005646-xhx9pzhj 1171 20 annual annual JJ cord-005646-xhx9pzhj 1171 21 paediathc paediathc NN cord-005646-xhx9pzhj 1171 22 admission admission NN cord-005646-xhx9pzhj 1171 23 of of IN cord-005646-xhx9pzhj 1171 24 4500 4500 CD cord-005646-xhx9pzhj 1171 25 patients patient NNS cord-005646-xhx9pzhj 1171 26 . . . cord-005646-xhx9pzhj 1172 1 Baragwanath Baragwanath NNP cord-005646-xhx9pzhj 1172 2 ICU ICU NNP cord-005646-xhx9pzhj 1172 3 admits admit VBZ cord-005646-xhx9pzhj 1172 4 250 250 CD cord-005646-xhx9pzhj 1172 5 non non JJ cord-005646-xhx9pzhj 1172 6 - - JJ cord-005646-xhx9pzhj 1172 7 neonatal neonatal JJ cord-005646-xhx9pzhj 1172 8 paediatdc paediatdc NN cord-005646-xhx9pzhj 1172 9 patients patient NNS cord-005646-xhx9pzhj 1172 10 per per IN cord-005646-xhx9pzhj 1172 11 year year NN cord-005646-xhx9pzhj 1172 12 . . . cord-005646-xhx9pzhj 1173 1 A a DT cord-005646-xhx9pzhj 1173 2 retrospective retrospective JJ cord-005646-xhx9pzhj 1173 3 chart chart NN cord-005646-xhx9pzhj 1173 4 review review NN cord-005646-xhx9pzhj 1173 5 from from IN cord-005646-xhx9pzhj 1173 6 January January NNP cord-005646-xhx9pzhj 1173 7 1991 1991 CD cord-005646-xhx9pzhj 1173 8 to to IN cord-005646-xhx9pzhj 1173 9 December December NNP cord-005646-xhx9pzhj 1173 10 1995 1995 CD cord-005646-xhx9pzhj 1173 11 of of IN cord-005646-xhx9pzhj 1173 12 42 42 CD cord-005646-xhx9pzhj 1173 13 consecutive consecutive JJ cord-005646-xhx9pzhj 1173 14 paedistdc paedistdc NN cord-005646-xhx9pzhj 1173 15 ICU ICU NNP cord-005646-xhx9pzhj 1173 16 admissions admission NNS cord-005646-xhx9pzhj 1173 17 with with IN cord-005646-xhx9pzhj 1173 18 bacterial bacterial JJ cord-005646-xhx9pzhj 1173 19 meningitis meningitis NN cord-005646-xhx9pzhj 1173 20 was be VBD cord-005646-xhx9pzhj 1173 21 performed perform VBN cord-005646-xhx9pzhj 1173 22 . . . cord-005646-xhx9pzhj 1174 1 RESULTS result NNS cord-005646-xhx9pzhj 1175 1 Approximately approximately RB cord-005646-xhx9pzhj 1175 2 150 150 CD cord-005646-xhx9pzhj 1175 3 cases case NNS cord-005646-xhx9pzhj 1175 4 of of IN cord-005646-xhx9pzhj 1175 5 bacterial bacterial JJ cord-005646-xhx9pzhj 1175 6 meningitis meningitis NN cord-005646-xhx9pzhj 1175 7 are be VBP cord-005646-xhx9pzhj 1175 8 admitted admit VBN cord-005646-xhx9pzhj 1175 9 to to IN cord-005646-xhx9pzhj 1175 10 the the DT cord-005646-xhx9pzhj 1175 11 general general JJ cord-005646-xhx9pzhj 1175 12 paediatric paediatric JJ cord-005646-xhx9pzhj 1175 13 wards ward NNS cord-005646-xhx9pzhj 1175 14 every every DT cord-005646-xhx9pzhj 1175 15 year year NN cord-005646-xhx9pzhj 1175 16 ; ; : cord-005646-xhx9pzhj 1175 17 this this DT cord-005646-xhx9pzhj 1175 18 constitutes constitute VBZ cord-005646-xhx9pzhj 1175 19 ± ± CD cord-005646-xhx9pzhj 1175 20 3 3 CD cord-005646-xhx9pzhj 1175 21 % % NN cord-005646-xhx9pzhj 1175 22 of of IN cord-005646-xhx9pzhj 1175 23 all all DT cord-005646-xhx9pzhj 1175 24 admissions admission NNS cord-005646-xhx9pzhj 1175 25 . . . cord-005646-xhx9pzhj 1176 1 The the DT cord-005646-xhx9pzhj 1176 2 mortality mortality NN cord-005646-xhx9pzhj 1176 3 of of IN cord-005646-xhx9pzhj 1176 4 these these DT cord-005646-xhx9pzhj 1176 5 patients patient NNS cord-005646-xhx9pzhj 1176 6 is be VBZ cord-005646-xhx9pzhj 1176 7 + + SYM cord-005646-xhx9pzhj 1176 8 14 14 CD cord-005646-xhx9pzhj 1176 9 % % NN cord-005646-xhx9pzhj 1176 10 . . . cord-005646-xhx9pzhj 1177 1 During during IN cord-005646-xhx9pzhj 1177 2 this this DT cord-005646-xhx9pzhj 1177 3 time time NN cord-005646-xhx9pzhj 1177 4 42 42 CD cord-005646-xhx9pzhj 1177 5 ( ( -LRB- cord-005646-xhx9pzhj 1177 6 23 23 CD cord-005646-xhx9pzhj 1177 7 M M NNP cord-005646-xhx9pzhj 1177 8 , , , cord-005646-xhx9pzhj 1177 9 19F 19F NNP cord-005646-xhx9pzhj 1177 10 ) ) -RRB- cord-005646-xhx9pzhj 1177 11 patients patient NNS cord-005646-xhx9pzhj 1177 12 ( ( -LRB- cord-005646-xhx9pzhj 1177 13 7 7 CD cord-005646-xhx9pzhj 1177 14 % % NN cord-005646-xhx9pzhj 1177 15 ) ) -RRB- cord-005646-xhx9pzhj 1177 16 were be VBD cord-005646-xhx9pzhj 1177 17 accepted accept VBN cord-005646-xhx9pzhj 1177 18 for for IN cord-005646-xhx9pzhj 1177 19 ICU ICU NNP cord-005646-xhx9pzhj 1177 20 admission admission NN cord-005646-xhx9pzhj 1177 21 , , , cord-005646-xhx9pzhj 1177 22 with with IN cord-005646-xhx9pzhj 1177 23 a a DT cord-005646-xhx9pzhj 1177 24 mortality mortality NN cord-005646-xhx9pzhj 1177 25 of of IN cord-005646-xhx9pzhj 1177 26 42.2 42.2 CD cord-005646-xhx9pzhj 1177 27 % % NN cord-005646-xhx9pzhj 1177 28 . . . cord-005646-xhx9pzhj 1178 1 The the DT cord-005646-xhx9pzhj 1178 2 median median JJ cord-005646-xhx9pzhj 1178 3 age age NN cord-005646-xhx9pzhj 1178 4 was be VBD cord-005646-xhx9pzhj 1178 5 9 9 CD cord-005646-xhx9pzhj 1178 6 months month NNS cord-005646-xhx9pzhj 1178 7 ( ( -LRB- cord-005646-xhx9pzhj 1178 8 range range VBP cord-005646-xhx9pzhj 1178 9 15 15 CD cord-005646-xhx9pzhj 1178 10 days day NNS cord-005646-xhx9pzhj 1178 11 to to IN cord-005646-xhx9pzhj 1178 12 17 17 CD cord-005646-xhx9pzhj 1178 13 years year NNS cord-005646-xhx9pzhj 1178 14 ) ) -RRB- cord-005646-xhx9pzhj 1178 15 . . . cord-005646-xhx9pzhj 1179 1 The the DT cord-005646-xhx9pzhj 1179 2 median median JJ cord-005646-xhx9pzhj 1179 3 delay delay NN cord-005646-xhx9pzhj 1179 4 to to IN cord-005646-xhx9pzhj 1179 5 hospital hospital NN cord-005646-xhx9pzhj 1179 6 admission admission NN cord-005646-xhx9pzhj 1179 7 was be VBD cord-005646-xhx9pzhj 1179 8 48 48 CD cord-005646-xhx9pzhj 1179 9 hours hour NNS cord-005646-xhx9pzhj 1179 10 , , , cord-005646-xhx9pzhj 1179 11 and and CC cord-005646-xhx9pzhj 1179 12 the the DT cord-005646-xhx9pzhj 1179 13 median median JJ cord-005646-xhx9pzhj 1179 14 delay delay NN cord-005646-xhx9pzhj 1179 15 to to IN cord-005646-xhx9pzhj 1179 16 ICU ICU NNP cord-005646-xhx9pzhj 1179 17 admission admission NN cord-005646-xhx9pzhj 1179 18 was be VBD cord-005646-xhx9pzhj 1179 19 a a DT cord-005646-xhx9pzhj 1179 20 further further JJ cord-005646-xhx9pzhj 1179 21 4 4 CD cord-005646-xhx9pzhj 1179 22 hours hour NNS cord-005646-xhx9pzhj 1179 23 . . . cord-005646-xhx9pzhj 1180 1 The the DT cord-005646-xhx9pzhj 1180 2 median median JJ cord-005646-xhx9pzhj 1180 3 duration duration NN cord-005646-xhx9pzhj 1180 4 of of IN cord-005646-xhx9pzhj 1180 5 tCU tCU NNP cord-005646-xhx9pzhj 1180 6 stay stay NN cord-005646-xhx9pzhj 1180 7 was be VBD cord-005646-xhx9pzhj 1180 8 48 48 CD cord-005646-xhx9pzhj 1180 9 hours hour NNS cord-005646-xhx9pzhj 1180 10 ( ( -LRB- cord-005646-xhx9pzhj 1180 11 40 40 CD cord-005646-xhx9pzhj 1180 12 for for IN cord-005646-xhx9pzhj 1180 13 non non NNS cord-005646-xhx9pzhj 1180 14 - - NNS cord-005646-xhx9pzhj 1180 15 survivors survivor NNS cord-005646-xhx9pzhj 1180 16 , , , cord-005646-xhx9pzhj 1180 17 120 120 CD cord-005646-xhx9pzhj 1180 18 for for IN cord-005646-xhx9pzhj 1180 19 survivors survivor NNS cord-005646-xhx9pzhj 1180 20 ) ) -RRB- cord-005646-xhx9pzhj 1180 21 . . . cord-005646-xhx9pzhj 1181 1 The the DT cord-005646-xhx9pzhj 1181 2 main main JJ cord-005646-xhx9pzhj 1181 3 presenting present VBG cord-005646-xhx9pzhj 1181 4 features feature NNS cord-005646-xhx9pzhj 1181 5 were be VBD cord-005646-xhx9pzhj 1181 6 convulsions convulsion NNS cord-005646-xhx9pzhj 1181 7 ( ( -LRB- cord-005646-xhx9pzhj 1181 8 34 34 CD cord-005646-xhx9pzhj 1181 9 % % NN cord-005646-xhx9pzhj 1181 10 ) ) -RRB- cord-005646-xhx9pzhj 1181 11 , , , cord-005646-xhx9pzhj 1181 12 altered alter VBN cord-005646-xhx9pzhj 1181 13 mental mental JJ cord-005646-xhx9pzhj 1181 14 state state NN cord-005646-xhx9pzhj 1181 15 ( ( -LRB- cord-005646-xhx9pzhj 1181 16 40 40 CD cord-005646-xhx9pzhj 1181 17 % % NN cord-005646-xhx9pzhj 1181 18 ) ) -RRB- cord-005646-xhx9pzhj 1181 19 , , , cord-005646-xhx9pzhj 1181 20 fever fever NN cord-005646-xhx9pzhj 1181 21 ( ( -LRB- cord-005646-xhx9pzhj 1181 22 50 50 CD cord-005646-xhx9pzhj 1181 23 % % NN cord-005646-xhx9pzhj 1181 24 ) ) -RRB- cord-005646-xhx9pzhj 1181 25 , , , cord-005646-xhx9pzhj 1181 26 respiratory respiratory JJ cord-005646-xhx9pzhj 1181 27 symptoms symptom NNS cord-005646-xhx9pzhj 1181 28 ( ( -LRB- cord-005646-xhx9pzhj 1181 29 24 24 CD cord-005646-xhx9pzhj 1181 30 % % NN cord-005646-xhx9pzhj 1181 31 ) ) -RRB- cord-005646-xhx9pzhj 1181 32 , , , cord-005646-xhx9pzhj 1181 33 headache headache NN cord-005646-xhx9pzhj 1181 34 ( ( -LRB- cord-005646-xhx9pzhj 1181 35 18 18 CD cord-005646-xhx9pzhj 1181 36 % % NN cord-005646-xhx9pzhj 1181 37 ) ) -RRB- cord-005646-xhx9pzhj 1181 38 , , , cord-005646-xhx9pzhj 1181 39 and and CC cord-005646-xhx9pzhj 1181 40 diarrhoea diarrhoea NN cord-005646-xhx9pzhj 1181 41 and and CC cord-005646-xhx9pzhj 1181 42 vomiting vomiting NN cord-005646-xhx9pzhj 1181 43 ( ( -LRB- cord-005646-xhx9pzhj 1181 44 32 32 CD cord-005646-xhx9pzhj 1181 45 % % NN cord-005646-xhx9pzhj 1181 46 ) ) -RRB- cord-005646-xhx9pzhj 1181 47 . . . cord-005646-xhx9pzhj 1182 1 The the DT cord-005646-xhx9pzhj 1182 2 most most RBS cord-005646-xhx9pzhj 1182 3 common common JJ cord-005646-xhx9pzhj 1182 4 indications indication NNS cord-005646-xhx9pzhj 1182 5 for for IN cord-005646-xhx9pzhj 1182 6 ICU ICU NNP cord-005646-xhx9pzhj 1182 7 admission admission NN cord-005646-xhx9pzhj 1182 8 were be VBD cord-005646-xhx9pzhj 1182 9 seizures seizure NNS cord-005646-xhx9pzhj 1182 10 ( ( -LRB- cord-005646-xhx9pzhj 1182 11 55 55 CD cord-005646-xhx9pzhj 1182 12 % % NN cord-005646-xhx9pzhj 1182 13 ) ) -RRB- cord-005646-xhx9pzhj 1182 14 , , , cord-005646-xhx9pzhj 1182 15 coma coma NN cord-005646-xhx9pzhj 1182 16 ( ( -LRB- cord-005646-xhx9pzhj 1182 17 36 36 CD cord-005646-xhx9pzhj 1182 18 % % NN cord-005646-xhx9pzhj 1182 19 ) ) -RRB- cord-005646-xhx9pzhj 1182 20 , , , cord-005646-xhx9pzhj 1182 21 shock shock NN cord-005646-xhx9pzhj 1182 22 ( ( -LRB- cord-005646-xhx9pzhj 1182 23 26 26 CD cord-005646-xhx9pzhj 1182 24 % % NN cord-005646-xhx9pzhj 1182 25 ) ) -RRB- cord-005646-xhx9pzhj 1182 26 , , , cord-005646-xhx9pzhj 1182 27 respiratory respiratory JJ cord-005646-xhx9pzhj 1182 28 failure failure NN cord-005646-xhx9pzhj 1182 29 ( ( -LRB- cord-005646-xhx9pzhj 1182 30 29 29 CD cord-005646-xhx9pzhj 1182 31 % % NN cord-005646-xhx9pzhj 1182 32 ) ) -RRB- cord-005646-xhx9pzhj 1182 33 and and CC cord-005646-xhx9pzhj 1182 34 acidosis acidosis NN cord-005646-xhx9pzhj 1182 35 ( ( -LRB- cord-005646-xhx9pzhj 1182 36 21 21 CD cord-005646-xhx9pzhj 1182 37 % % NN cord-005646-xhx9pzhj 1182 38 ) ) -RRB- cord-005646-xhx9pzhj 1182 39 . . . cord-005646-xhx9pzhj 1183 1 In in IN cord-005646-xhx9pzhj 1183 2 29 29 CD cord-005646-xhx9pzhj 1183 3 % % NN cord-005646-xhx9pzhj 1183 4 of of IN cord-005646-xhx9pzhj 1183 5 patients patient NNS cord-005646-xhx9pzhj 1183 6 there there EX cord-005646-xhx9pzhj 1183 7 was be VBD cord-005646-xhx9pzhj 1183 8 a a DT cord-005646-xhx9pzhj 1183 9 cardiorespirstory cardiorespirstory JJ cord-005646-xhx9pzhj 1183 10 arrest arrest NN cord-005646-xhx9pzhj 1183 11 prior prior RB cord-005646-xhx9pzhj 1183 12 to to IN cord-005646-xhx9pzhj 1183 13 admission admission NN cord-005646-xhx9pzhj 1183 14 . . . cord-005646-xhx9pzhj 1184 1 The the DT cord-005646-xhx9pzhj 1184 2 most most RBS cord-005646-xhx9pzhj 1184 3 common common JJ cord-005646-xhx9pzhj 1184 4 organisms organism NNS cord-005646-xhx9pzhj 1184 5 in in IN cord-005646-xhx9pzhj 1184 6 the the DT cord-005646-xhx9pzhj 1184 7 CSF CSF NNP cord-005646-xhx9pzhj 1184 8 was be VBD cord-005646-xhx9pzhj 1184 9 pneumococcus pneumococcus NNP cord-005646-xhx9pzhj 1184 10 ( ( -LRB- cord-005646-xhx9pzhj 1184 11 57 57 CD cord-005646-xhx9pzhj 1184 12 % % NN cord-005646-xhx9pzhj 1184 13 ) ) -RRB- cord-005646-xhx9pzhj 1184 14 , , , cord-005646-xhx9pzhj 1184 15 haemophilus haemophilus NN cord-005646-xhx9pzhj 1184 16 influenza influenza NN cord-005646-xhx9pzhj 1184 17 ( ( -LRB- cord-005646-xhx9pzhj 1184 18 15 15 CD cord-005646-xhx9pzhj 1184 19 % % NN cord-005646-xhx9pzhj 1184 20 ) ) -RRB- cord-005646-xhx9pzhj 1184 21 and and CC cord-005646-xhx9pzhj 1184 22 E e NN cord-005646-xhx9pzhj 1184 23 coli coli NNS cord-005646-xhx9pzhj 1184 24 ( ( -LRB- cord-005646-xhx9pzhj 1184 25 12 12 CD cord-005646-xhx9pzhj 1184 26 % % NN cord-005646-xhx9pzhj 1184 27 ) ) -RRB- cord-005646-xhx9pzhj 1184 28 . . . cord-005646-xhx9pzhj 1185 1 The the DT cord-005646-xhx9pzhj 1185 2 presence presence NN cord-005646-xhx9pzhj 1185 3 of of IN cord-005646-xhx9pzhj 1185 4 leucopenia leucopenia NNP cord-005646-xhx9pzhj 1185 5 ( ( -LRB- cord-005646-xhx9pzhj 1185 6 WCC WCC NNP cord-005646-xhx9pzhj 1185 7 < < XX cord-005646-xhx9pzhj 1185 8 5 5 CD cord-005646-xhx9pzhj 1185 9 ) ) -RRB- cord-005646-xhx9pzhj 1185 10 , , , cord-005646-xhx9pzhj 1185 11 a a DT cord-005646-xhx9pzhj 1185 12 low low JJ cord-005646-xhx9pzhj 1185 13 platelat platelat JJ cord-005646-xhx9pzhj 1185 14 count count NN cord-005646-xhx9pzhj 1185 15 ( ( -LRB- cord-005646-xhx9pzhj 1185 16 < < NNP cord-005646-xhx9pzhj 1185 17 100 100 CD cord-005646-xhx9pzhj 1185 18 ) ) -RRB- cord-005646-xhx9pzhj 1185 19 , , , cord-005646-xhx9pzhj 1185 20 acidaemia acidaemia NNP cord-005646-xhx9pzhj 1185 21 ( ( -LRB- cord-005646-xhx9pzhj 1185 22 pH<7.2 pH<7.2 NNP cord-005646-xhx9pzhj 1185 23 ) ) -RRB- cord-005646-xhx9pzhj 1185 24 , , , cord-005646-xhx9pzhj 1185 25 and and CC cord-005646-xhx9pzhj 1185 26 the the DT cord-005646-xhx9pzhj 1185 27 need need NN cord-005646-xhx9pzhj 1185 28 for for IN cord-005646-xhx9pzhj 1185 29 inotropic inotropic NNP cord-005646-xhx9pzhj 1185 30 support support NN cord-005646-xhx9pzhj 1185 31 were be VBD cord-005646-xhx9pzhj 1185 32 strongly strongly RB cord-005646-xhx9pzhj 1185 33 associated associate VBN cord-005646-xhx9pzhj 1185 34 with with IN cord-005646-xhx9pzhj 1185 35 nonsurvival nonsurvival NNP cord-005646-xhx9pzhj 1185 36 . . . cord-005646-xhx9pzhj 1186 1 Tachycardia tachycardia JJ cord-005646-xhx9pzhj 1186 2 and and CC cord-005646-xhx9pzhj 1186 3 hypotension hypotension NN cord-005646-xhx9pzhj 1186 4 were be VBD cord-005646-xhx9pzhj 1186 5 not not RB cord-005646-xhx9pzhj 1186 6 significantly significantly RB cord-005646-xhx9pzhj 1186 7 essorJsted essorjste VBN cord-005646-xhx9pzhj 1186 8 with with IN cord-005646-xhx9pzhj 1186 9 poor poor JJ cord-005646-xhx9pzhj 1186 10 outcome outcome NN cord-005646-xhx9pzhj 1186 11 , , , cord-005646-xhx9pzhj 1186 12 as as IN cord-005646-xhx9pzhj 1186 13 has have VBZ cord-005646-xhx9pzhj 1186 14 been be VBN cord-005646-xhx9pzhj 1186 15 previously previously RB cord-005646-xhx9pzhj 1186 16 reported report VBN cord-005646-xhx9pzhj 1186 17 . . . cord-005646-xhx9pzhj 1187 1 DISCUSSION DISCUSSION NNP cord-005646-xhx9pzhj 1187 2 Early early JJ cord-005646-xhx9pzhj 1187 3 diagnosis diagnosis NN cord-005646-xhx9pzhj 1187 4 of of IN cord-005646-xhx9pzhj 1187 5 meningitis meningitis NN cord-005646-xhx9pzhj 1187 6 and and CC cord-005646-xhx9pzhj 1187 7 prompt prompt JJ cord-005646-xhx9pzhj 1187 8 institution institution NN cord-005646-xhx9pzhj 1187 9 of of IN cord-005646-xhx9pzhj 1187 10 antibiotic antibiotic JJ cord-005646-xhx9pzhj 1187 11 therapy therapy NN cord-005646-xhx9pzhj 1187 12 requires require VBZ cord-005646-xhx9pzhj 1187 13 a a DT cord-005646-xhx9pzhj 1187 14 high high JJ cord-005646-xhx9pzhj 1187 15 level level NN cord-005646-xhx9pzhj 1187 16 of of IN cord-005646-xhx9pzhj 1187 17 clinical clinical JJ cord-005646-xhx9pzhj 1187 18 suspicion suspicion NN cord-005646-xhx9pzhj 1187 19 . . . cord-005646-xhx9pzhj 1188 1 Paediatric paediatric JJ cord-005646-xhx9pzhj 1188 2 patients patient NNS cord-005646-xhx9pzhj 1188 3 with with IN cord-005646-xhx9pzhj 1188 4 bacterial bacterial JJ cord-005646-xhx9pzhj 1188 5 meningitis meningitis NN cord-005646-xhx9pzhj 1188 6 that that WDT cord-005646-xhx9pzhj 1188 7 require require VBP cord-005646-xhx9pzhj 1188 8 mechanical mechanical JJ cord-005646-xhx9pzhj 1188 9 ventilation ventilation NN cord-005646-xhx9pzhj 1188 10 have have VBP cord-005646-xhx9pzhj 1188 11 a a DT cord-005646-xhx9pzhj 1188 12 poor poor JJ cord-005646-xhx9pzhj 1188 13 prognosis prognosis NN cord-005646-xhx9pzhj 1188 14 . . . cord-005646-xhx9pzhj 1189 1 There there EX cord-005646-xhx9pzhj 1189 2 is be VBZ cord-005646-xhx9pzhj 1189 3 little little JJ cord-005646-xhx9pzhj 1189 4 evidence evidence NN cord-005646-xhx9pzhj 1189 5 to to TO cord-005646-xhx9pzhj 1189 6 suggest suggest VB cord-005646-xhx9pzhj 1189 7 that that IN cord-005646-xhx9pzhj 1189 8 nomsurviva nomsurviva NN cord-005646-xhx9pzhj 1189 9 [ [ -LRB- cord-005646-xhx9pzhj 1189 10 can can MD cord-005646-xhx9pzhj 1189 11 be be VB cord-005646-xhx9pzhj 1189 12 predicted predict VBN cord-005646-xhx9pzhj 1189 13 prior prior RB cord-005646-xhx9pzhj 1189 14 to to IN cord-005646-xhx9pzhj 1189 15 ICU ICU NNP cord-005646-xhx9pzhj 1189 16 admission admission NN cord-005646-xhx9pzhj 1189 17 , , , cord-005646-xhx9pzhj 1189 18 but but CC cord-005646-xhx9pzhj 1189 19 a a DT cord-005646-xhx9pzhj 1189 20 rapid rapid JJ cord-005646-xhx9pzhj 1189 21 deterioration deterioration NN cord-005646-xhx9pzhj 1189 22 requiring require VBG cord-005646-xhx9pzhj 1189 23 ventilation ventilation NN cord-005646-xhx9pzhj 1189 24 and and CC cord-005646-xhx9pzhj 1189 25 inotrepic inotrepic JJ cord-005646-xhx9pzhj 1189 26 support support NN cord-005646-xhx9pzhj 1189 27 with with IN cord-005646-xhx9pzhj 1189 28 evidence evidence NN cord-005646-xhx9pzhj 1189 29 of of IN cord-005646-xhx9pzhj 1189 30 severe severe JJ cord-005646-xhx9pzhj 1189 31 sepsis sepsis NN cord-005646-xhx9pzhj 1189 32 ( ( -LRB- cord-005646-xhx9pzhj 1189 33 low low JJ cord-005646-xhx9pzhj 1189 34 platelet platelet NN cord-005646-xhx9pzhj 1189 35 count count NN cord-005646-xhx9pzhj 1189 36 , , , cord-005646-xhx9pzhj 1189 37 leucopenia leucopenia NNP cord-005646-xhx9pzhj 1189 38 ) ) -RRB- cord-005646-xhx9pzhj 1190 1 is be VBZ cord-005646-xhx9pzhj 1190 2 Nmost Nmost NNP cord-005646-xhx9pzhj 1190 3 invariably invariably RB cord-005646-xhx9pzhj 1190 4 associated associate VBD cord-005646-xhx9pzhj 1190 5 with with IN cord-005646-xhx9pzhj 1190 6 a a DT cord-005646-xhx9pzhj 1190 7 fatal fatal JJ cord-005646-xhx9pzhj 1190 8 outcome outcome NN cord-005646-xhx9pzhj 1190 9 . . . cord-005646-xhx9pzhj 1191 1 The the DT cord-005646-xhx9pzhj 1191 2 long long JJ cord-005646-xhx9pzhj 1191 3 term term NN cord-005646-xhx9pzhj 1191 4 functional functional JJ cord-005646-xhx9pzhj 1191 5 outcome outcome NN cord-005646-xhx9pzhj 1191 6 of of IN cord-005646-xhx9pzhj 1191 7 these these DT cord-005646-xhx9pzhj 1191 8 patients patient NNS cord-005646-xhx9pzhj 1191 9 make make VBP cord-005646-xhx9pzhj 1191 10 this this DT cord-005646-xhx9pzhj 1191 11 disease disease NN cord-005646-xhx9pzhj 1191 12 even even RB cord-005646-xhx9pzhj 1191 13 more more RBR cord-005646-xhx9pzhj 1191 14 devastating devastating JJ cord-005646-xhx9pzhj 1191 15 ; ; : cord-005646-xhx9pzhj 1191 16 the the DT cord-005646-xhx9pzhj 1191 17 rote rote NN cord-005646-xhx9pzhj 1191 18 of of IN cord-005646-xhx9pzhj 1191 19 ICU ICU NNP cord-005646-xhx9pzhj 1191 20 in in IN cord-005646-xhx9pzhj 1191 21 the the DT cord-005646-xhx9pzhj 1191 22 management management NN cord-005646-xhx9pzhj 1191 23 of of IN cord-005646-xhx9pzhj 1191 24 these these DT cord-005646-xhx9pzhj 1191 25 patients patient NNS cord-005646-xhx9pzhj 1191 26 has have VBZ cord-005646-xhx9pzhj 1191 27 yet yet RB cord-005646-xhx9pzhj 1191 28 to to TO cord-005646-xhx9pzhj 1191 29 be be VB cord-005646-xhx9pzhj 1191 30 fully fully RB cord-005646-xhx9pzhj 1191 31 estaNished estanishe VBN cord-005646-xhx9pzhj 1191 32 . . . cord-005646-xhx9pzhj 1192 1 Objective objective JJ cord-005646-xhx9pzhj 1192 2 and and CC cord-005646-xhx9pzhj 1192 3 study study NN cord-005646-xhx9pzhj 1192 4 design design NN cord-005646-xhx9pzhj 1192 5 : : : cord-005646-xhx9pzhj 1192 6 A a DT cord-005646-xhx9pzhj 1192 7 retrospective retrospective JJ cord-005646-xhx9pzhj 1192 8 study study NN cord-005646-xhx9pzhj 1192 9 was be VBD cord-005646-xhx9pzhj 1192 10 pertbrmed pertbrmed JJ cord-005646-xhx9pzhj 1192 11 for for IN cord-005646-xhx9pzhj 1192 12 all all DT cord-005646-xhx9pzhj 1192 13 patients patient NNS cord-005646-xhx9pzhj 1192 14 diagnosed diagnose VBN cord-005646-xhx9pzhj 1192 15 with with IN cord-005646-xhx9pzhj 1192 16 hemorrhagic hemorrhagic JJ cord-005646-xhx9pzhj 1192 17 shock shock NN cord-005646-xhx9pzhj 1192 18 and and CC cord-005646-xhx9pzhj 1192 19 encephalopathy encephalopathy NN cord-005646-xhx9pzhj 1192 20 syndrome syndrome NN cord-005646-xhx9pzhj 1192 21 ( ( -LRB- cord-005646-xhx9pzhj 1192 22 HSE HSE NNP cord-005646-xhx9pzhj 1192 23 ) ) -RRB- cord-005646-xhx9pzhj 1192 24 during during IN cord-005646-xhx9pzhj 1192 25 1984 1984 CD cord-005646-xhx9pzhj 1192 26 to to IN cord-005646-xhx9pzhj 1192 27 1994 1994 CD cord-005646-xhx9pzhj 1192 28 . . . cord-005646-xhx9pzhj 1193 1 Soroka Soroka NNP cord-005646-xhx9pzhj 1193 2 Medical Medical NNP cord-005646-xhx9pzhj 1193 3 Center Center NNP cord-005646-xhx9pzhj 1193 4 is be VBZ cord-005646-xhx9pzhj 1193 5 the the DT cord-005646-xhx9pzhj 1193 6 only only JJ cord-005646-xhx9pzhj 1193 7 medical medical JJ cord-005646-xhx9pzhj 1193 8 facility facility NN cord-005646-xhx9pzhj 1193 9 in in IN cord-005646-xhx9pzhj 1193 10 the the DT cord-005646-xhx9pzhj 1193 11 southern southern JJ cord-005646-xhx9pzhj 1193 12 Negev Negev NNP cord-005646-xhx9pzhj 1193 13 region region NN cord-005646-xhx9pzhj 1193 14 of of IN cord-005646-xhx9pzhj 1193 15 Israel Israel NNP cord-005646-xhx9pzhj 1193 16 serving serve VBG cord-005646-xhx9pzhj 1193 17 a a DT cord-005646-xhx9pzhj 1193 18 population population NN cord-005646-xhx9pzhj 1193 19 of of IN cord-005646-xhx9pzhj 1193 20 -400,000 -400,000 ADD cord-005646-xhx9pzhj 1193 21 residents resident NNS cord-005646-xhx9pzhj 1193 22 , , , cord-005646-xhx9pzhj 1193 23 consisting consist VBG cord-005646-xhx9pzhj 1193 24 primarily primarily RB cord-005646-xhx9pzhj 1193 25 of of IN cord-005646-xhx9pzhj 1193 26 Jews Jews NNPS cord-005646-xhx9pzhj 1193 27 and and CC cord-005646-xhx9pzhj 1193 28 Bedouins Bedouins NNPS cord-005646-xhx9pzhj 1193 29 . . . cord-005646-xhx9pzhj 1194 1 Results result NNS cord-005646-xhx9pzhj 1194 2 : : : cord-005646-xhx9pzhj 1195 1 20 20 CD cord-005646-xhx9pzhj 1195 2 patients patient NNS cord-005646-xhx9pzhj 1195 3 ( ( -LRB- cord-005646-xhx9pzhj 1195 4 17 17 CD cord-005646-xhx9pzhj 1195 5 Bedouins Bedouins NNPS cord-005646-xhx9pzhj 1195 6 and and CC cord-005646-xhx9pzhj 1195 7 3 3 CD cord-005646-xhx9pzhj 1195 8 Jews Jews NNPS cord-005646-xhx9pzhj 1195 9 ) ) -RRB- cord-005646-xhx9pzhj 1195 10 were be VBD cord-005646-xhx9pzhj 1195 11 diagnosed diagnose VBN cord-005646-xhx9pzhj 1195 12 with with IN cord-005646-xhx9pzhj 1195 13 HSE HSE NNP cord-005646-xhx9pzhj 1195 14 . . . cord-005646-xhx9pzhj 1196 1 Main main JJ cord-005646-xhx9pzhj 1196 2 features feature NNS cord-005646-xhx9pzhj 1196 3 on on IN cord-005646-xhx9pzhj 1196 4 arrival arrival NN cord-005646-xhx9pzhj 1196 5 included include VBD cord-005646-xhx9pzhj 1196 6 profound profound JJ cord-005646-xhx9pzhj 1196 7 shock shock NN cord-005646-xhx9pzhj 1196 8 and and CC cord-005646-xhx9pzhj 1196 9 coma coma NN cord-005646-xhx9pzhj 1196 10 with with IN cord-005646-xhx9pzhj 1196 11 con con NN cord-005646-xhx9pzhj 1196 12 ~ ~ NNP cord-005646-xhx9pzhj 1196 13 alsions alsion NNS cord-005646-xhx9pzhj 1196 14 . . . cord-005646-xhx9pzhj 1197 1 Active active JJ cord-005646-xhx9pzhj 1197 2 bleeding bleeding NN cord-005646-xhx9pzhj 1197 3 and/or and/or CC cord-005646-xhx9pzhj 1197 4 disturbing disturbing JJ cord-005646-xhx9pzhj 1197 5 coagulation coagulation NN cord-005646-xhx9pzhj 1197 6 tests test NNS cord-005646-xhx9pzhj 1197 7 with with IN cord-005646-xhx9pzhj 1197 8 falling fall VBG cord-005646-xhx9pzhj 1197 9 heuroglobin heuroglobin NN cord-005646-xhx9pzhj 1197 10 levels level NNS cord-005646-xhx9pzhj 1197 11 and and CC cord-005646-xhx9pzhj 1197 12 thrombocytopenia thrombocytopenia NN cord-005646-xhx9pzhj 1197 13 was be VBD cord-005646-xhx9pzhj 1197 14 noted note VBN cord-005646-xhx9pzhj 1197 15 in in IN cord-005646-xhx9pzhj 1197 16 every every DT cord-005646-xhx9pzhj 1197 17 case case NN cord-005646-xhx9pzhj 1197 18 . . . cord-005646-xhx9pzhj 1198 1 All all DT cord-005646-xhx9pzhj 1198 2 infants infant NNS cord-005646-xhx9pzhj 1198 3 developed develop VBD cord-005646-xhx9pzhj 1198 4 diarrhea diarrhea NN cord-005646-xhx9pzhj 1198 5 shortly shortly RB cord-005646-xhx9pzhj 1198 6 after after IN cord-005646-xhx9pzhj 1198 7 arrival arrival NN cord-005646-xhx9pzhj 1198 8 . . . cord-005646-xhx9pzhj 1199 1 Elevated elevated JJ cord-005646-xhx9pzhj 1199 2 urea urea NN cord-005646-xhx9pzhj 1199 3 , , , cord-005646-xhx9pzhj 1199 4 creatinine creatinine NN cord-005646-xhx9pzhj 1199 5 and and CC cord-005646-xhx9pzhj 1199 6 liver liver NN cord-005646-xhx9pzhj 1199 7 enzymes enzyme NNS cord-005646-xhx9pzhj 1199 8 was be VBD cord-005646-xhx9pzhj 1199 9 noted note VBN cord-005646-xhx9pzhj 1199 10 in in IN cord-005646-xhx9pzhj 1199 11 all all DT cord-005646-xhx9pzhj 1199 12 cases case NNS cord-005646-xhx9pzhj 1199 13 . . . cord-005646-xhx9pzhj 1200 1 Annual annual JJ cord-005646-xhx9pzhj 1200 2 incidence incidence NN cord-005646-xhx9pzhj 1200 3 tbr tbr NNP cord-005646-xhx9pzhj 1200 4 inlhnts inlhnts NNP cord-005646-xhx9pzhj 1200 5 < < NNP cord-005646-xhx9pzhj 1200 6 1 1 CD cord-005646-xhx9pzhj 1200 7 year year NN cord-005646-xhx9pzhj 1200 8 of of IN cord-005646-xhx9pzhj 1200 9 age age NN cord-005646-xhx9pzhj 1200 10 was be VBD cord-005646-xhx9pzhj 1200 11 5:10,000 5:10,000 CD cord-005646-xhx9pzhj 1200 12 for for IN cord-005646-xhx9pzhj 1200 13 Bedouins Bedouins NNPS cord-005646-xhx9pzhj 1200 14 and and CC cord-005646-xhx9pzhj 1200 15 0.6:10,000 0.6:10,000 . cord-005646-xhx9pzhj 1201 1 for for IN cord-005646-xhx9pzhj 1201 2 Jews Jews NNPS cord-005646-xhx9pzhj 1201 3 . . . cord-005646-xhx9pzhj 1202 1 Patients patient NNS cord-005646-xhx9pzhj 1202 2 ranged range VBD cord-005646-xhx9pzhj 1202 3 in in IN cord-005646-xhx9pzhj 1202 4 age age NN cord-005646-xhx9pzhj 1202 5 from from IN cord-005646-xhx9pzhj 1202 6 6 6 CD cord-005646-xhx9pzhj 1202 7 - - SYM cord-005646-xhx9pzhj 1202 8 32 32 CD cord-005646-xhx9pzhj 1202 9 wks wks NN cord-005646-xhx9pzhj 1202 10 and and CC cord-005646-xhx9pzhj 1202 11 arrived arrive VBD cord-005646-xhx9pzhj 1202 12 at at IN cord-005646-xhx9pzhj 1202 13 the the DT cord-005646-xhx9pzhj 1202 14 hospital hospital NN cord-005646-xhx9pzhj 1202 15 late late JJ cord-005646-xhx9pzhj 1202 16 night night NN cord-005646-xhx9pzhj 1202 17 / / SYM cord-005646-xhx9pzhj 1202 18 early early JJ cord-005646-xhx9pzhj 1202 19 morning morning NN cord-005646-xhx9pzhj 1202 20 ( ( -LRB- cord-005646-xhx9pzhj 1202 21 2:00am 2:00am CD cord-005646-xhx9pzhj 1202 22 - - HYPH cord-005646-xhx9pzhj 1202 23 ll:00am ll:00am RB cord-005646-xhx9pzhj 1202 24 ) ) -RRB- cord-005646-xhx9pzhj 1202 25 , , , cord-005646-xhx9pzhj 1202 26 during during IN cord-005646-xhx9pzhj 1202 27 winter winter NN cord-005646-xhx9pzhj 1202 28 / / SYM cord-005646-xhx9pzhj 1202 29 early early JJ cord-005646-xhx9pzhj 1202 30 spring spring NN cord-005646-xhx9pzhj 1202 31 ( ( -LRB- cord-005646-xhx9pzhj 1202 32 November November NNP cord-005646-xhx9pzhj 1202 33 - - HYPH cord-005646-xhx9pzhj 1202 34 April April NNP cord-005646-xhx9pzhj 1202 35 ) ) -RRB- cord-005646-xhx9pzhj 1202 36 . . . cord-005646-xhx9pzhj 1203 1 All all DT cord-005646-xhx9pzhj 1203 2 were be VBD cord-005646-xhx9pzhj 1203 3 healthy healthy JJ cord-005646-xhx9pzhj 1203 4 prior prior RB cord-005646-xhx9pzhj 1203 5 to to IN cord-005646-xhx9pzhj 1203 6 admission admission NN cord-005646-xhx9pzhj 1203 7 , , , cord-005646-xhx9pzhj 1203 8 with with IN cord-005646-xhx9pzhj 1203 9 short short JJ cord-005646-xhx9pzhj 1203 10 prodromal prodromal JJ cord-005646-xhx9pzhj 1203 11 symptoms symptom NNS cord-005646-xhx9pzhj 1203 12 of of IN cord-005646-xhx9pzhj 1203 13 upper upper JJ cord-005646-xhx9pzhj 1203 14 respiratory respiratory JJ cord-005646-xhx9pzhj 1203 15 tract tract NN cord-005646-xhx9pzhj 1203 16 or or CC cord-005646-xhx9pzhj 1203 17 gastrointestinal gastrointestinal JJ cord-005646-xhx9pzhj 1203 18 infection infection NN cord-005646-xhx9pzhj 1203 19 noted note VBN cord-005646-xhx9pzhj 1203 20 in in IN cord-005646-xhx9pzhj 1203 21 10 10 CD cord-005646-xhx9pzhj 1203 22 cases case NNS cord-005646-xhx9pzhj 1203 23 . . . cord-005646-xhx9pzhj 1204 1 Most Most JJS cord-005646-xhx9pzhj 1204 2 infants infant NNS cord-005646-xhx9pzhj 1204 3 had have VBD cord-005646-xhx9pzhj 1204 4 markedly markedly RB cord-005646-xhx9pzhj 1204 5 elevated elevate VBN cord-005646-xhx9pzhj 1204 6 body body NN cord-005646-xhx9pzhj 1204 7 temperature temperature NN cord-005646-xhx9pzhj 1204 8 on on IN cord-005646-xhx9pzhj 1204 9 arrival arrival NN cord-005646-xhx9pzhj 1204 10 . . . cord-005646-xhx9pzhj 1205 1 A a DT cord-005646-xhx9pzhj 1205 2 history history NN cord-005646-xhx9pzhj 1205 3 of of IN cord-005646-xhx9pzhj 1205 4 overwrapping overwrappe VBG cord-005646-xhx9pzhj 1205 5 and/or and/or CC cord-005646-xhx9pzhj 1205 6 excessive excessive JJ cord-005646-xhx9pzhj 1205 7 hearing hearing NN cord-005646-xhx9pzhj 1205 8 was be VBD cord-005646-xhx9pzhj 1205 9 obtained obtain VBN cord-005646-xhx9pzhj 1205 10 in in IN cord-005646-xhx9pzhj 1205 11 4 4 CD cord-005646-xhx9pzhj 1205 12 of of IN cord-005646-xhx9pzhj 1205 13 20 20 CD cord-005646-xhx9pzhj 1205 14 infants infant NNS cord-005646-xhx9pzhj 1205 15 . . . cord-005646-xhx9pzhj 1206 1 Bacteriological bacteriological JJ cord-005646-xhx9pzhj 1206 2 and and CC cord-005646-xhx9pzhj 1206 3 virological virological JJ cord-005646-xhx9pzhj 1206 4 cultures culture NNS cord-005646-xhx9pzhj 1206 5 were be VBD cord-005646-xhx9pzhj 1206 6 negative negative JJ cord-005646-xhx9pzhj 1206 7 in in IN cord-005646-xhx9pzhj 1206 8 all all DT cord-005646-xhx9pzhj 1206 9 infants infant NNS cord-005646-xhx9pzhj 1206 10 . . . cord-005646-xhx9pzhj 1207 1 One one CD cord-005646-xhx9pzhj 1207 2 infant infant NN cord-005646-xhx9pzhj 1207 3 died die VBD cord-005646-xhx9pzhj 1207 4 and and CC cord-005646-xhx9pzhj 1207 5 neurological neurological JJ cord-005646-xhx9pzhj 1207 6 sequelae sequela NNS cord-005646-xhx9pzhj 1207 7 were be VBD cord-005646-xhx9pzhj 1207 8 observed observe VBN cord-005646-xhx9pzhj 1207 9 in in IN cord-005646-xhx9pzhj 1207 10 all all DT cord-005646-xhx9pzhj 1207 11 survivors survivor NNS cord-005646-xhx9pzhj 1207 12 . . . cord-005646-xhx9pzhj 1208 1 The the DT cord-005646-xhx9pzhj 1208 2 high high JJ cord-005646-xhx9pzhj 1208 3 prevalence prevalence NN cord-005646-xhx9pzhj 1208 4 of of IN cord-005646-xhx9pzhj 1208 5 hyperpyrexia hyperpyrexia NN cord-005646-xhx9pzhj 1208 6 during during IN cord-005646-xhx9pzhj 1208 7 sleep sleep NN cord-005646-xhx9pzhj 1208 8 in in IN cord-005646-xhx9pzhj 1208 9 the the DT cord-005646-xhx9pzhj 1208 10 presence presence NN cord-005646-xhx9pzhj 1208 11 of of IN cord-005646-xhx9pzhj 1208 12 negative negative JJ cord-005646-xhx9pzhj 1208 13 microbiological microbiological JJ cord-005646-xhx9pzhj 1208 14 results result NNS cord-005646-xhx9pzhj 1208 15 with with IN cord-005646-xhx9pzhj 1208 16 no no DT cord-005646-xhx9pzhj 1208 17 evidence evidence NN cord-005646-xhx9pzhj 1208 18 of of IN cord-005646-xhx9pzhj 1208 19 excessive excessive JJ cord-005646-xhx9pzhj 1208 20 hearing hearing NN cord-005646-xhx9pzhj 1208 21 , , , cord-005646-xhx9pzhj 1208 22 and and CC cord-005646-xhx9pzhj 1208 23 the the DT cord-005646-xhx9pzhj 1208 24 high high JJ cord-005646-xhx9pzhj 1208 25 incidence incidence NN cord-005646-xhx9pzhj 1208 26 of of IN cord-005646-xhx9pzhj 1208 27 riSE riSE NNP cord-005646-xhx9pzhj 1208 28 among among IN cord-005646-xhx9pzhj 1208 29 a a DT cord-005646-xhx9pzhj 1208 30 closed closed JJ cord-005646-xhx9pzhj 1208 31 , , , cord-005646-xhx9pzhj 1208 32 culturally culturally RB cord-005646-xhx9pzhj 1208 33 isolated isolate VBN cord-005646-xhx9pzhj 1208 34 society society NN cord-005646-xhx9pzhj 1208 35 known know VBN cord-005646-xhx9pzhj 1208 36 to to TO cord-005646-xhx9pzhj 1208 37 have have VB cord-005646-xhx9pzhj 1208 38 a a DT cord-005646-xhx9pzhj 1208 39 high high JJ cord-005646-xhx9pzhj 1208 40 incidence incidence NN cord-005646-xhx9pzhj 1208 41 of of IN cord-005646-xhx9pzhj 1208 42 congenital congenital JJ cord-005646-xhx9pzhj 1208 43 malformations malformation NNS cord-005646-xhx9pzhj 1208 44 , , , cord-005646-xhx9pzhj 1208 45 may may MD cord-005646-xhx9pzhj 1208 46 support support VB cord-005646-xhx9pzhj 1208 47 previous previous JJ cord-005646-xhx9pzhj 1208 48 assumptions assumption NNS cord-005646-xhx9pzhj 1208 49 that that WDT cord-005646-xhx9pzhj 1208 50 HSE HSE NNP cord-005646-xhx9pzhj 1208 51 results result VBZ cord-005646-xhx9pzhj 1208 52 from from IN cord-005646-xhx9pzhj 1208 53 hyqperpyrexia hyqperpyrexia NN cord-005646-xhx9pzhj 1208 54 , , , cord-005646-xhx9pzhj 1208 55 originating originate VBG cord-005646-xhx9pzhj 1208 56 in in IN cord-005646-xhx9pzhj 1208 57 most most JJS cord-005646-xhx9pzhj 1208 58 cases case NNS cord-005646-xhx9pzhj 1208 59 from from IN cord-005646-xhx9pzhj 1208 60 a a DT cord-005646-xhx9pzhj 1208 61 " " `` cord-005646-xhx9pzhj 1208 62 physiologic physiologic JJ cord-005646-xhx9pzhj 1208 63 " " '' cord-005646-xhx9pzhj 1208 64 heat heat NN cord-005646-xhx9pzhj 1208 65 induced induce VBN cord-005646-xhx9pzhj 1208 66 trigger trigger NN cord-005646-xhx9pzhj 1208 67 which which WDT cord-005646-xhx9pzhj 1208 68 starts start VBZ cord-005646-xhx9pzhj 1208 69 and and CC cord-005646-xhx9pzhj 1208 70 peaks peak NNS cord-005646-xhx9pzhj 1208 71 during during IN cord-005646-xhx9pzhj 1208 72 the the DT cord-005646-xhx9pzhj 1208 73 night night NN cord-005646-xhx9pzhj 1208 74 in in IN cord-005646-xhx9pzhj 1208 75 previously previously RB cord-005646-xhx9pzhj 1208 76 healthy healthy JJ cord-005646-xhx9pzhj 1208 77 infants infant NNS cord-005646-xhx9pzhj 1208 78 with with IN cord-005646-xhx9pzhj 1208 79 susceptible susceptible JJ cord-005646-xhx9pzhj 1208 80 , , , cord-005646-xhx9pzhj 1208 81 predisposing predispose VBG cord-005646-xhx9pzhj 1208 82 genetic genetic JJ cord-005646-xhx9pzhj 1208 83 underlie underlie NNS cord-005646-xhx9pzhj 1208 84 . . . cord-005646-xhx9pzhj 1209 1 Approximately approximately RB cord-005646-xhx9pzhj 1209 2 10 10 CD cord-005646-xhx9pzhj 1209 3 % % NN cord-005646-xhx9pzhj 1209 4 of of IN cord-005646-xhx9pzhj 1209 5 hospitalised hospitalise VBN cord-005646-xhx9pzhj 1209 6 infants infant NNS cord-005646-xhx9pzhj 1209 7 with with IN cord-005646-xhx9pzhj 1209 8 respiratory respiratory JJ cord-005646-xhx9pzhj 1209 9 syaacytial syaacytial JJ cord-005646-xhx9pzhj 1209 10 virus virus NN cord-005646-xhx9pzhj 1209 11 ( ( -LRB- cord-005646-xhx9pzhj 1209 12 RSV RSV NNP cord-005646-xhx9pzhj 1209 13 ) ) -RRB- cord-005646-xhx9pzhj 1209 14 infection infection NN cord-005646-xhx9pzhj 1209 15 require require VBP cord-005646-xhx9pzhj 1209 16 mechanical mechanical JJ cord-005646-xhx9pzhj 1209 17 ventilation ventilation NN cord-005646-xhx9pzhj 1209 18 . . . cord-005646-xhx9pzhj 1210 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 1210 2 general general JJ cord-005646-xhx9pzhj 1210 3 practice practice NN cord-005646-xhx9pzhj 1210 4 is be VBZ cord-005646-xhx9pzhj 1210 5 not not RB cord-005646-xhx9pzhj 1210 6 to to TO cord-005646-xhx9pzhj 1210 7 use use VB cord-005646-xhx9pzhj 1210 8 specific specific JJ cord-005646-xhx9pzhj 1210 9 antiviral antiviral JJ cord-005646-xhx9pzhj 1210 10 therapy therapy NN cord-005646-xhx9pzhj 1210 11 . . . cord-005646-xhx9pzhj 1211 1 We -PRON- PRP cord-005646-xhx9pzhj 1211 2 have have VBP cord-005646-xhx9pzhj 1211 3 undertaken undertake VBN cord-005646-xhx9pzhj 1211 4 studies study NNS cord-005646-xhx9pzhj 1211 5 of of IN cord-005646-xhx9pzhj 1211 6 RSV RSV NNP cord-005646-xhx9pzhj 1211 7 - - HYPH cord-005646-xhx9pzhj 1211 8 infected infect VBN cord-005646-xhx9pzhj 1211 9 mechanically mechanically RB cord-005646-xhx9pzhj 1211 10 ventilated ventilate VBN cord-005646-xhx9pzhj 1211 11 patients patient NNS cord-005646-xhx9pzhj 1211 12 without without IN cord-005646-xhx9pzhj 1211 13 underlying underlie VBG cord-005646-xhx9pzhj 1211 14 congenital congenital JJ cord-005646-xhx9pzhj 1211 15 heart heart NN cord-005646-xhx9pzhj 1211 16 disease disease NN cord-005646-xhx9pzhj 1211 17 or or CC cord-005646-xhx9pzhj 1211 18 immunodeficiency immunodeficiency NN cord-005646-xhx9pzhj 1211 19 . . . cord-005646-xhx9pzhj 1212 1 Study study NN cord-005646-xhx9pzhj 1212 2 I -PRON- PRP cord-005646-xhx9pzhj 1212 3 ( ( -LRB- cord-005646-xhx9pzhj 1212 4 n=45 n=45 NNS cord-005646-xhx9pzhj 1212 5 ) ) -RRB- cord-005646-xhx9pzhj 1212 6 : : : cord-005646-xhx9pzhj 1213 1 A a DT cord-005646-xhx9pzhj 1213 2 retrospective retrospective JJ cord-005646-xhx9pzhj 1213 3 review review NN cord-005646-xhx9pzhj 1213 4 of of IN cord-005646-xhx9pzhj 1213 5 45 45 CD cord-005646-xhx9pzhj 1213 6 infants infant NNS cord-005646-xhx9pzhj 1213 7 ( ( -LRB- cord-005646-xhx9pzhj 1213 8 mean mean VB cord-005646-xhx9pzhj 1213 9 post post JJ cord-005646-xhx9pzhj 1213 10 - - JJ cord-005646-xhx9pzhj 1213 11 conceptual conceptual JJ cord-005646-xhx9pzhj 1213 12 age age NN cord-005646-xhx9pzhj 1213 13 48 48 CD cord-005646-xhx9pzhj 1213 14 weeks week NNS cord-005646-xhx9pzhj 1213 15 ; ; : cord-005646-xhx9pzhj 1213 16 median median JJ cord-005646-xhx9pzhj 1213 17 duration duration NN cord-005646-xhx9pzhj 1213 18 of of IN cord-005646-xhx9pzhj 1213 19 intubation intubation NN cord-005646-xhx9pzhj 1213 20 was be VBD cord-005646-xhx9pzhj 1213 21 8 8 CD cord-005646-xhx9pzhj 1213 22 days day NNS cord-005646-xhx9pzhj 1213 23 ( ( -LRB- cord-005646-xhx9pzhj 1213 24 interquartile interquartile JJ cord-005646-xhx9pzhj 1213 25 range range NN cord-005646-xhx9pzhj 1213 26 5 5 CD cord-005646-xhx9pzhj 1213 27 - - SYM cord-005646-xhx9pzhj 1213 28 11 11 CD cord-005646-xhx9pzhj 1213 29 ) ) -RRB- cord-005646-xhx9pzhj 1213 30 . . . cord-005646-xhx9pzhj 1214 1 Blinded blinded JJ cord-005646-xhx9pzhj 1214 2 review review NN cord-005646-xhx9pzhj 1214 3 of of IN cord-005646-xhx9pzhj 1214 4 chest chest NN cord-005646-xhx9pzhj 1214 5 x x NNS cord-005646-xhx9pzhj 1214 6 - - NNS cord-005646-xhx9pzhj 1214 7 rays ray NNS cord-005646-xhx9pzhj 1214 8 during during IN cord-005646-xhx9pzhj 1214 9 the the DT cord-005646-xhx9pzhj 1214 10 first first JJ cord-005646-xhx9pzhj 1214 11 three three CD cord-005646-xhx9pzhj 1214 12 days day NNS cord-005646-xhx9pzhj 1214 13 of of IN cord-005646-xhx9pzhj 1214 14 mechanical mechanical JJ cord-005646-xhx9pzhj 1214 15 ventilation ventilation NN cord-005646-xhx9pzhj 1214 16 revealed reveal VBD cord-005646-xhx9pzhj 1214 17 a a DT cord-005646-xhx9pzhj 1214 18 spectrmn spectrmn NN cord-005646-xhx9pzhj 1214 19 of of IN cord-005646-xhx9pzhj 1214 20 lower low JJR cord-005646-xhx9pzhj 1214 21 respiratory respiratory JJ cord-005646-xhx9pzhj 1214 22 tract tract NN cord-005646-xhx9pzhj 1214 23 findings finding NNS cord-005646-xhx9pzhj 1214 24 from from IN cord-005646-xhx9pzhj 1214 25 marked marked JJ cord-005646-xhx9pzhj 1214 26 diffiase diffiase NN cord-005646-xhx9pzhj 1214 27 consolidation consolidation NN cord-005646-xhx9pzhj 1214 28 in in IN cord-005646-xhx9pzhj 1214 29 all all DT cord-005646-xhx9pzhj 1214 30 zones zone NNS cord-005646-xhx9pzhj 1214 31 without without IN cord-005646-xhx9pzhj 1214 32 hyper hyper NN cord-005646-xhx9pzhj 1214 33 - - NN cord-005646-xhx9pzhj 1214 34 inflation inflation NN cord-005646-xhx9pzhj 1214 35 ( ( -LRB- cord-005646-xhx9pzhj 1214 36 n=10 n=10 NNP cord-005646-xhx9pzhj 1214 37 ) ) -RRB- cord-005646-xhx9pzhj 1214 38 to to IN cord-005646-xhx9pzhj 1214 39 gross gross JJ cord-005646-xhx9pzhj 1214 40 hyperinfiation hyperinfiation NN cord-005646-xhx9pzhj 1214 41 without without IN cord-005646-xhx9pzhj 1214 42 consolidation consolidation NN cord-005646-xhx9pzhj 1214 43 ( ( -LRB- cord-005646-xhx9pzhj 1214 44 n=5 n=5 NNP cord-005646-xhx9pzhj 1214 45 ) ) -RRB- cord-005646-xhx9pzhj 1214 46 , , , cord-005646-xhx9pzhj 1214 47 with with IN cord-005646-xhx9pzhj 1214 48 the the DT cord-005646-xhx9pzhj 1214 49 remaining remain VBG cord-005646-xhx9pzhj 1214 50 patients patient NNS cord-005646-xhx9pzhj 1214 51 have have VBP cord-005646-xhx9pzhj 1214 52 an an DT cord-005646-xhx9pzhj 1214 53 intermediate intermediate JJ cord-005646-xhx9pzhj 1214 54 picture picture NN cord-005646-xhx9pzhj 1214 55 ( ( -LRB- cord-005646-xhx9pzhj 1214 56 n=30 n=30 NNP cord-005646-xhx9pzhj 1214 57 ) ) -RRB- cord-005646-xhx9pzhj 1214 58 . . . cord-005646-xhx9pzhj 1215 1 Death death NN cord-005646-xhx9pzhj 1215 2 occurred occur VBD cord-005646-xhx9pzhj 1215 3 only only RB cord-005646-xhx9pzhj 1215 4 in in IN cord-005646-xhx9pzhj 1215 5 patients patient NNS cord-005646-xhx9pzhj 1215 6 who who WP cord-005646-xhx9pzhj 1215 7 were be VBD cord-005646-xhx9pzhj 1215 8 at at IN cord-005646-xhx9pzhj 1215 9 the the DT cord-005646-xhx9pzhj 1215 10 poles pole NNS cord-005646-xhx9pzhj 1215 11 of of IN cord-005646-xhx9pzhj 1215 12 this this DT cord-005646-xhx9pzhj 1215 13 continuum continuum NN cord-005646-xhx9pzhj 1215 14 ( ( -LRB- cord-005646-xhx9pzhj 1215 15 4/10 4/10 CD cord-005646-xhx9pzhj 1215 16 consolidation consolidation NN cord-005646-xhx9pzhj 1215 17 and and CC cord-005646-xhx9pzhj 1215 18 1/5 1/5 CD cord-005646-xhx9pzhj 1215 19 hyperinflation hyperinflation NN cord-005646-xhx9pzhj 1215 20 ) ) -RRB- cord-005646-xhx9pzhj 1215 21 . . . cord-005646-xhx9pzhj 1216 1 Patients patient NNS cord-005646-xhx9pzhj 1216 2 at at IN cord-005646-xhx9pzhj 1216 3 these these DT cord-005646-xhx9pzhj 1216 4 poles pole NNS cord-005646-xhx9pzhj 1216 5 could could MD cord-005646-xhx9pzhj 1216 6 be be VB cord-005646-xhx9pzhj 1216 7 differentiated differentiate VBN cord-005646-xhx9pzhj 1216 8 by by IN cord-005646-xhx9pzhj 1216 9 gender gender NN cord-005646-xhx9pzhj 1216 10 predominance predominance NN cord-005646-xhx9pzhj 1216 11 , , , cord-005646-xhx9pzhj 1216 12 birth birth NN cord-005646-xhx9pzhj 1216 13 gestation gestation NN cord-005646-xhx9pzhj 1216 14 , , , cord-005646-xhx9pzhj 1216 15 alveolar alveolar NN cord-005646-xhx9pzhj 1216 16 - - HYPH cord-005646-xhx9pzhj 1216 17 artarial artarial JJ cord-005646-xhx9pzhj 1216 18 ( ( -LRB- cord-005646-xhx9pzhj 1216 19 A a NN cord-005646-xhx9pzhj 1216 20 - - HYPH cord-005646-xhx9pzhj 1216 21 a a DT cord-005646-xhx9pzhj 1216 22 ) ) -RRB- cord-005646-xhx9pzhj 1216 23 oxygen oxygen NN cord-005646-xhx9pzhj 1216 24 gradient gradient NN cord-005646-xhx9pzhj 1216 25 ( ( -LRB- cord-005646-xhx9pzhj 1216 26 p<0.0 p<0.0 NNP cord-005646-xhx9pzhj 1216 27 l l NNP cord-005646-xhx9pzhj 1216 28 ) ) -RRB- cord-005646-xhx9pzhj 1216 29 , , , cord-005646-xhx9pzhj 1216 30 oxygenation oxygenation NN cord-005646-xhx9pzhj 1216 31 index index NN cord-005646-xhx9pzhj 1216 32 ( ( -LRB- cord-005646-xhx9pzhj 1216 33 p<0.0 p<0.0 NNP cord-005646-xhx9pzhj 1216 34 l l NNP cord-005646-xhx9pzhj 1216 35 ) ) -RRB- cord-005646-xhx9pzhj 1216 36 , , , cord-005646-xhx9pzhj 1216 37 peak peak JJ cord-005646-xhx9pzhj 1216 38 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1216 39 pressure pressure NN cord-005646-xhx9pzhj 1216 40 ( ( -LRB- cord-005646-xhx9pzhj 1216 41 p<0.05 p<0.05 NNP cord-005646-xhx9pzhj 1216 42 ) ) -RRB- cord-005646-xhx9pzhj 1216 43 , , , cord-005646-xhx9pzhj 1216 44 and and CC cord-005646-xhx9pzhj 1216 45 intubation intubation NN cord-005646-xhx9pzhj 1216 46 days day NNS cord-005646-xhx9pzhj 1216 47 ( ( -LRB- cord-005646-xhx9pzhj 1216 48 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 1216 49 ) ) -RRB- cord-005646-xhx9pzhj 1216 50 . . . cord-005646-xhx9pzhj 1217 1 Study Study NNP cord-005646-xhx9pzhj 1217 2 II II NNP cord-005646-xhx9pzhj 1217 3 ( ( -LRB- cord-005646-xhx9pzhj 1217 4 n=28 n=28 NN cord-005646-xhx9pzhj 1217 5 ) ) -RRB- cord-005646-xhx9pzhj 1217 6 : : : cord-005646-xhx9pzhj 1218 1 Prospective prospective JJ cord-005646-xhx9pzhj 1218 2 audit audit NN cord-005646-xhx9pzhj 1218 3 of of IN cord-005646-xhx9pzhj 1218 4 infants infant NNS cord-005646-xhx9pzhj 1218 5 with with IN cord-005646-xhx9pzhj 1218 6 the the DT cord-005646-xhx9pzhj 1218 7 aim aim NN cord-005646-xhx9pzhj 1218 8 of of IN cord-005646-xhx9pzhj 1218 9 verifying verify VBG cord-005646-xhx9pzhj 1218 10 the the DT cord-005646-xhx9pzhj 1218 11 above above JJ cord-005646-xhx9pzhj 1218 12 differentiation differentiation NN cord-005646-xhx9pzhj 1218 13 . . . cord-005646-xhx9pzhj 1219 1 Separating separate VBG cord-005646-xhx9pzhj 1219 2 patients patient NNS cord-005646-xhx9pzhj 1219 3 based base VBN cord-005646-xhx9pzhj 1219 4 on on IN cord-005646-xhx9pzhj 1219 5 their -PRON- PRP$ cord-005646-xhx9pzhj 1219 6 early early JJ cord-005646-xhx9pzhj 1219 7 x x NNS cord-005646-xhx9pzhj 1219 8 - - NNS cord-005646-xhx9pzhj 1219 9 rays ray NNS cord-005646-xhx9pzhj 1219 10 and and CC cord-005646-xhx9pzhj 1219 11 A a NN cord-005646-xhx9pzhj 1219 12 - - : cord-005646-xhx9pzhj 1219 13 a a DT cord-005646-xhx9pzhj 1219 14 gradient gradient NN cord-005646-xhx9pzhj 1219 15 we -PRON- PRP cord-005646-xhx9pzhj 1219 16 confirmed confirm VBD cord-005646-xhx9pzhj 1219 17 the the DT cord-005646-xhx9pzhj 1219 18 above above JJ cord-005646-xhx9pzhj 1219 19 predictable predictable JJ cord-005646-xhx9pzhj 1219 20 difference difference NN cord-005646-xhx9pzhj 1219 21 in in IN cord-005646-xhx9pzhj 1219 22 duration duration NN cord-005646-xhx9pzhj 1219 23 of of IN cord-005646-xhx9pzhj 1219 24 supportive supportive JJ cord-005646-xhx9pzhj 1219 25 therapy therapy NN cord-005646-xhx9pzhj 1219 26 ( ( -LRB- cord-005646-xhx9pzhj 1219 27 consolidation consolidation NN cord-005646-xhx9pzhj 1219 28 v v IN cord-005646-xhx9pzhj 1219 29 intermediate intermediate NN cord-005646-xhx9pzhj 1219 30 : : : cord-005646-xhx9pzhj 1219 31 6(4 6(4 NNP cord-005646-xhx9pzhj 1219 32 - - HYPH cord-005646-xhx9pzhj 1219 33 7 7 CD cord-005646-xhx9pzhj 1219 34 ) ) -RRB- cord-005646-xhx9pzhj 1219 35 v v NN cord-005646-xhx9pzhj 1219 36 14 14 CD cord-005646-xhx9pzhj 1219 37 ( ( -LRB- cord-005646-xhx9pzhj 1219 38 12 12 CD cord-005646-xhx9pzhj 1219 39 - - SYM cord-005646-xhx9pzhj 1219 40 33 33 CD cord-005646-xhx9pzhj 1219 41 ) ) -RRB- cord-005646-xhx9pzhj 1219 42 p<0.01 p<0.01 NN cord-005646-xhx9pzhj 1219 43 ) ) -RRB- cord-005646-xhx9pzhj 1219 44 . . . cord-005646-xhx9pzhj 1220 1 Severe severe JJ cord-005646-xhx9pzhj 1220 2 lower low JJR cord-005646-xhx9pzhj 1220 3 respiratory respiratory JJ cord-005646-xhx9pzhj 1220 4 tract tract NN cord-005646-xhx9pzhj 1220 5 RSV rsv NN cord-005646-xhx9pzhj 1220 6 - - HYPH cord-005646-xhx9pzhj 1220 7 infecrion infecrion NN cord-005646-xhx9pzhj 1220 8 in in IN cord-005646-xhx9pzhj 1220 9 young young JJ cord-005646-xhx9pzhj 1220 10 infants infant NNS cord-005646-xhx9pzhj 1220 11 results result VBZ cord-005646-xhx9pzhj 1220 12 in in IN cord-005646-xhx9pzhj 1220 13 different different JJ cord-005646-xhx9pzhj 1220 14 distinctive distinctive JJ cord-005646-xhx9pzhj 1220 15 partems partem NNS cord-005646-xhx9pzhj 1220 16 of of IN cord-005646-xhx9pzhj 1220 17 disease disease NN cord-005646-xhx9pzhj 1220 18 with with IN cord-005646-xhx9pzhj 1220 19 characteristic characteristic JJ cord-005646-xhx9pzhj 1220 20 radiological radiological JJ cord-005646-xhx9pzhj 1220 21 and and CC cord-005646-xhx9pzhj 1220 22 clinical clinical JJ cord-005646-xhx9pzhj 1220 23 features feature NNS cord-005646-xhx9pzhj 1220 24 , , , cord-005646-xhx9pzhj 1220 25 and and CC cord-005646-xhx9pzhj 1220 26 each each DT cord-005646-xhx9pzhj 1220 27 has have VBZ cord-005646-xhx9pzhj 1220 28 a a DT cord-005646-xhx9pzhj 1220 29 predictable predictable JJ cord-005646-xhx9pzhj 1220 30 timecot timecot NNS cord-005646-xhx9pzhj 1220 31 ~ ~ NFP cord-005646-xhx9pzhj 1220 32 se se FW cord-005646-xhx9pzhj 1220 33 . . . cord-005646-xhx9pzhj 1221 1 Conflicting conflict VBG cord-005646-xhx9pzhj 1221 2 reports report NNS cord-005646-xhx9pzhj 1221 3 on on IN cord-005646-xhx9pzhj 1221 4 special special JJ cord-005646-xhx9pzhj 1221 5 therapy therapy NN cord-005646-xhx9pzhj 1221 6 should should MD cord-005646-xhx9pzhj 1221 7 be be VB cord-005646-xhx9pzhj 1221 8 interpreted interpret VBN cord-005646-xhx9pzhj 1221 9 with with IN cord-005646-xhx9pzhj 1221 10 respect respect NN cord-005646-xhx9pzhj 1221 11 to to IN cord-005646-xhx9pzhj 1221 12 these these DT cord-005646-xhx9pzhj 1221 13 observations observation NNS cord-005646-xhx9pzhj 1221 14 before before IN cord-005646-xhx9pzhj 1221 15 making make VBG cord-005646-xhx9pzhj 1221 16 conclusions conclusion NNS cord-005646-xhx9pzhj 1221 17 about about IN cord-005646-xhx9pzhj 1221 18 the the DT cord-005646-xhx9pzhj 1221 19 efficacy efficacy NN cord-005646-xhx9pzhj 1221 20 of of IN cord-005646-xhx9pzhj 1221 21 any any DT cord-005646-xhx9pzhj 1221 22 specific specific JJ cord-005646-xhx9pzhj 1221 23 treatment treatment NN cord-005646-xhx9pzhj 1221 24 . . . cord-005646-xhx9pzhj 1221 25 _SP cord-005646-xhx9pzhj 1222 1 The the DT cord-005646-xhx9pzhj 1222 2 clinical clinical JJ cord-005646-xhx9pzhj 1222 3 data datum NNS cord-005646-xhx9pzhj 1222 4 of of IN cord-005646-xhx9pzhj 1222 5 186 186 CD cord-005646-xhx9pzhj 1222 6 children child NNS cord-005646-xhx9pzhj 1222 7 wich wich RB cord-005646-xhx9pzhj 1222 8 suffered suffer VBD cord-005646-xhx9pzhj 1222 9 from from IN cord-005646-xhx9pzhj 1222 10 a a DT cord-005646-xhx9pzhj 1222 11 severe severe JJ cord-005646-xhx9pzhj 1222 12 mycosis mycosis NN cord-005646-xhx9pzhj 1222 13 between between IN cord-005646-xhx9pzhj 1222 14 Jan.1990-Dac.1994 Jan.1990-Dac.1994 NNPS cord-005646-xhx9pzhj 1222 15 and and CC cord-005646-xhx9pzhj 1222 16 wich wich WP cord-005646-xhx9pzhj 1222 17 were be VBD cord-005646-xhx9pzhj 1222 18 treated treat VBN cord-005646-xhx9pzhj 1222 19 with with IN cord-005646-xhx9pzhj 1222 20 amphotericin amphotericin NNS cord-005646-xhx9pzhj 1222 21 B B NNP cord-005646-xhx9pzhj 1222 22 in in IN cord-005646-xhx9pzhj 1222 23 10 10 CD cord-005646-xhx9pzhj 1222 24 spanish spanish JJ cord-005646-xhx9pzhj 1222 25 hospitals hospital NNS cord-005646-xhx9pzhj 1222 26 were be VBD cord-005646-xhx9pzhj 1222 27 collected collect VBN cord-005646-xhx9pzhj 1222 28 . . . cord-005646-xhx9pzhj 1223 1 Mean mean JJ cord-005646-xhx9pzhj 1223 2 age age NN cord-005646-xhx9pzhj 1223 3 was be VBD cord-005646-xhx9pzhj 1223 4 6 6 CD cord-005646-xhx9pzhj 1223 5 + + SYM cord-005646-xhx9pzhj 1223 6 3.9 3.9 CD cord-005646-xhx9pzhj 1223 7 years year NNS cord-005646-xhx9pzhj 1223 8 ; ; : cord-005646-xhx9pzhj 1223 9 157 157 CD cord-005646-xhx9pzhj 1223 10 were be VBD cord-005646-xhx9pzhj 1223 11 mate mate NN cord-005646-xhx9pzhj 1223 12 ( ( -LRB- cord-005646-xhx9pzhj 1223 13 84 84 CD cord-005646-xhx9pzhj 1223 14 % % NN cord-005646-xhx9pzhj 1223 15 ) ) -RRB- cord-005646-xhx9pzhj 1223 16 and and CC cord-005646-xhx9pzhj 1223 17 29 29 CD cord-005646-xhx9pzhj 1223 18 female female NN cord-005646-xhx9pzhj 1223 19 ( ( -LRB- cord-005646-xhx9pzhj 1223 20 16 16 CD cord-005646-xhx9pzhj 1223 21 % % NN cord-005646-xhx9pzhj 1223 22 ) ) -RRB- cord-005646-xhx9pzhj 1223 23 . . . cord-005646-xhx9pzhj 1224 1 The the DT cord-005646-xhx9pzhj 1224 2 most most RBS cord-005646-xhx9pzhj 1224 3 common common JJ cord-005646-xhx9pzhj 1224 4 underlying underlie VBG cord-005646-xhx9pzhj 1224 5 diseases disease NNS cord-005646-xhx9pzhj 1224 6 were be VBD cord-005646-xhx9pzhj 1224 7 leukemiMymphoma leukemiMymphoma NNP cord-005646-xhx9pzhj 1224 8 ( ( -LRB- cord-005646-xhx9pzhj 1224 9 31 31 CD cord-005646-xhx9pzhj 1224 10 % % NN cord-005646-xhx9pzhj 1224 11 ) ) -RRB- cord-005646-xhx9pzhj 1224 12 and and CC cord-005646-xhx9pzhj 1224 13 congenital congenital JJ cord-005646-xhx9pzhj 1224 14 heart heart NN cord-005646-xhx9pzhj 1224 15 defects defect NNS cord-005646-xhx9pzhj 1224 16 ( ( -LRB- cord-005646-xhx9pzhj 1224 17 20 20 CD cord-005646-xhx9pzhj 1224 18 % % NN cord-005646-xhx9pzhj 1224 19 ) ) -RRB- cord-005646-xhx9pzhj 1224 20 . . . cord-005646-xhx9pzhj 1225 1 The the DT cord-005646-xhx9pzhj 1225 2 major major JJ cord-005646-xhx9pzhj 1225 3 pathogens pathogen NNS cord-005646-xhx9pzhj 1225 4 isolated isolate VBN cord-005646-xhx9pzhj 1225 5 were be VBD cord-005646-xhx9pzhj 1225 6 candida candida NN cord-005646-xhx9pzhj 1225 7 albieans albiean NNS cord-005646-xhx9pzhj 1225 8 ( ( -LRB- cord-005646-xhx9pzhj 1225 9 61 61 CD cord-005646-xhx9pzhj 1225 10 % % NN cord-005646-xhx9pzhj 1225 11 ) ) -RRB- cord-005646-xhx9pzhj 1225 12 , , , cord-005646-xhx9pzhj 1225 13 other other JJ cord-005646-xhx9pzhj 1225 14 candida candida NN cord-005646-xhx9pzhj 1225 15 ( ( -LRB- cord-005646-xhx9pzhj 1225 16 18 18 CD cord-005646-xhx9pzhj 1225 17 % % NN cord-005646-xhx9pzhj 1225 18 ) ) -RRB- cord-005646-xhx9pzhj 1225 19 and and CC cord-005646-xhx9pzhj 1225 20 aspergillus aspergillus NN cord-005646-xhx9pzhj 1225 21 ( ( -LRB- cord-005646-xhx9pzhj 1225 22 17 17 CD cord-005646-xhx9pzhj 1225 23 % % NN cord-005646-xhx9pzhj 1225 24 ) ) -RRB- cord-005646-xhx9pzhj 1225 25 . . . cord-005646-xhx9pzhj 1226 1 and and CC cord-005646-xhx9pzhj 1226 2 liposomal liposomal IN cord-005646-xhx9pzhj 1226 3 amphotericin amphotericin NNP cord-005646-xhx9pzhj 1226 4 ( ( -LRB- cord-005646-xhx9pzhj 1226 5 LA LA NNP cord-005646-xhx9pzhj 1226 6 ) ) -RRB- cord-005646-xhx9pzhj 1226 7 in in IN cord-005646-xhx9pzhj 1226 8 68 68 CD cord-005646-xhx9pzhj 1226 9 ( ( -LRB- cord-005646-xhx9pzhj 1226 10 37 37 CD cord-005646-xhx9pzhj 1226 11 % % NN cord-005646-xhx9pzhj 1226 12 ) ) -RRB- cord-005646-xhx9pzhj 1226 13 . . . cord-005646-xhx9pzhj 1227 1 In in IN cord-005646-xhx9pzhj 1227 2 the the DT cord-005646-xhx9pzhj 1227 3 CA CA NNP cord-005646-xhx9pzhj 1227 4 group group NN cord-005646-xhx9pzhj 1227 5 , , , cord-005646-xhx9pzhj 1227 6 the the DT cord-005646-xhx9pzhj 1227 7 starting starting NN cord-005646-xhx9pzhj 1227 8 dose dose NN cord-005646-xhx9pzhj 1227 9 was be VBD cord-005646-xhx9pzhj 1227 10 0,3~0,1 0,3~0,1 CD cord-005646-xhx9pzhj 1227 11 mg mg NNP cord-005646-xhx9pzhj 1227 12 / / SYM cord-005646-xhx9pzhj 1227 13 kg kg NNP cord-005646-xhx9pzhj 1227 14 , , , cord-005646-xhx9pzhj 1227 15 reaching reach VBG cord-005646-xhx9pzhj 1227 16 a a DT cord-005646-xhx9pzhj 1227 17 maximal maximal JJ cord-005646-xhx9pzhj 1227 18 dose dose NN cord-005646-xhx9pzhj 1227 19 of of IN cord-005646-xhx9pzhj 1227 20 0.9 0.9 CD cord-005646-xhx9pzhj 1227 21 + + SYM cord-005646-xhx9pzhj 1227 22 0,3 0,3 CD cord-005646-xhx9pzhj 1227 23 mg mg NNP cord-005646-xhx9pzhj 1227 24 / / SYM cord-005646-xhx9pzhj 1227 25 kg kg NNP cord-005646-xhx9pzhj 1227 26 after after IN cord-005646-xhx9pzhj 1227 27 4.7 4.7 CD cord-005646-xhx9pzhj 1227 28 + + SYM cord-005646-xhx9pzhj 1227 29 3 3 CD cord-005646-xhx9pzhj 1227 30 days day NNS cord-005646-xhx9pzhj 1227 31 . . . cord-005646-xhx9pzhj 1228 1 Maintenance maintenance NN cord-005646-xhx9pzhj 1228 2 time time NN cord-005646-xhx9pzhj 1228 3 was be VBD cord-005646-xhx9pzhj 1228 4 14 14 CD cord-005646-xhx9pzhj 1228 5 + + SYM cord-005646-xhx9pzhj 1228 6 10 10 CD cord-005646-xhx9pzhj 1228 7 days day NNS cord-005646-xhx9pzhj 1228 8 and and CC cord-005646-xhx9pzhj 1228 9 the the DT cord-005646-xhx9pzhj 1228 10 cumulative cumulative JJ cord-005646-xhx9pzhj 1228 11 dose dose NN cord-005646-xhx9pzhj 1228 12 : : : cord-005646-xhx9pzhj 1228 13 12~17 12~17 CD cord-005646-xhx9pzhj 1228 14 rag rag NN cord-005646-xhx9pzhj 1228 15 . . . cord-005646-xhx9pzhj 1229 1 In in IN cord-005646-xhx9pzhj 1229 2 the the DT cord-005646-xhx9pzhj 1229 3 LA LA NNP cord-005646-xhx9pzhj 1229 4 group group NN cord-005646-xhx9pzhj 1229 5 , , , cord-005646-xhx9pzhj 1229 6 the the DT cord-005646-xhx9pzhj 1229 7 starting starting NN cord-005646-xhx9pzhj 1229 8 dose dose NN cord-005646-xhx9pzhj 1229 9 was be VBD cord-005646-xhx9pzhj 1229 10 1.1±1 1.1±1 CD cord-005646-xhx9pzhj 1229 11 mg mg NNP cord-005646-xhx9pzhj 1229 12 / / SYM cord-005646-xhx9pzhj 1229 13 kg kg NNP cord-005646-xhx9pzhj 1229 14 , , , cord-005646-xhx9pzhj 1229 15 reaching reach VBG cord-005646-xhx9pzhj 1229 16 a a DT cord-005646-xhx9pzhj 1229 17 maximal maximal JJ cord-005646-xhx9pzhj 1229 18 dose dose NN cord-005646-xhx9pzhj 1229 19 of of IN cord-005646-xhx9pzhj 1229 20 2.9_+2.4 2.9_+2.4 CD cord-005646-xhx9pzhj 1229 21 mg mg NNP cord-005646-xhx9pzhj 1229 22 / / SYM cord-005646-xhx9pzhj 1229 23 kg kg NNP cord-005646-xhx9pzhj 1229 24 ( ( -LRB- cord-005646-xhx9pzhj 1229 25 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 1229 26 ) ) -RRB- cord-005646-xhx9pzhj 1229 27 after after IN cord-005646-xhx9pzhj 1229 28 5 5 CD cord-005646-xhx9pzhj 1229 29 + + SYM cord-005646-xhx9pzhj 1229 30 5 5 CD cord-005646-xhx9pzhj 1229 31 days day NNS cord-005646-xhx9pzhj 1229 32 . . . cord-005646-xhx9pzhj 1230 1 Maintenance maintenance NN cord-005646-xhx9pzhj 1230 2 time time NN cord-005646-xhx9pzhj 1230 3 was be VBD cord-005646-xhx9pzhj 1230 4 19~16 19~16 CD cord-005646-xhx9pzhj 1230 5 days day NNS cord-005646-xhx9pzhj 1230 6 ( ( -LRB- cord-005646-xhx9pzhj 1230 7 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1230 8 ) ) -RRB- cord-005646-xhx9pzhj 1230 9 and and CC cord-005646-xhx9pzhj 1230 10 the the DT cord-005646-xhx9pzhj 1230 11 cumulative cumulative JJ cord-005646-xhx9pzhj 1230 12 dose dose NN cord-005646-xhx9pzhj 1230 13 42_+37 42_+37 CD cord-005646-xhx9pzhj 1230 14 mg mg NNP cord-005646-xhx9pzhj 1230 15 ( ( -LRB- cord-005646-xhx9pzhj 1230 16 p<0.05 p<0.05 NNP cord-005646-xhx9pzhj 1230 17 ) ) -RRB- cord-005646-xhx9pzhj 1230 18 . . . cord-005646-xhx9pzhj 1231 1 The the DT cord-005646-xhx9pzhj 1231 2 reasons reason NNS cord-005646-xhx9pzhj 1231 3 for for IN cord-005646-xhx9pzhj 1231 4 LA LA NNP cord-005646-xhx9pzhj 1231 5 use use NN cord-005646-xhx9pzhj 1231 6 were be VBD cord-005646-xhx9pzhj 1231 7 : : : cord-005646-xhx9pzhj 1231 8 elective elective JJ cord-005646-xhx9pzhj 1231 9 in in IN cord-005646-xhx9pzhj 1231 10 66 66 CD cord-005646-xhx9pzhj 1231 11 % % NN cord-005646-xhx9pzhj 1231 12 of of IN cord-005646-xhx9pzhj 1231 13 cases case NNS cord-005646-xhx9pzhj 1231 14 , , , cord-005646-xhx9pzhj 1231 15 previous previous JJ cord-005646-xhx9pzhj 1231 16 renal renal JJ cord-005646-xhx9pzhj 1231 17 failure failure NN cord-005646-xhx9pzhj 1231 18 in in IN cord-005646-xhx9pzhj 1231 19 29 29 CD cord-005646-xhx9pzhj 1231 20 % % NN cord-005646-xhx9pzhj 1231 21 , , , cord-005646-xhx9pzhj 1231 22 and and CC cord-005646-xhx9pzhj 1231 23 CA CA NNP cord-005646-xhx9pzhj 1231 24 inefficacy inefficacy NN cord-005646-xhx9pzhj 1231 25 in in IN cord-005646-xhx9pzhj 1231 26 4 4 CD cord-005646-xhx9pzhj 1231 27 % % NN cord-005646-xhx9pzhj 1231 28 . . . cord-005646-xhx9pzhj 1232 1 Hepatic hepatic JJ cord-005646-xhx9pzhj 1232 2 or or CC cord-005646-xhx9pzhj 1232 3 renal renal JJ cord-005646-xhx9pzhj 1232 4 function function NN cord-005646-xhx9pzhj 1232 5 impairment impairment NN cord-005646-xhx9pzhj 1232 6 was be VBD cord-005646-xhx9pzhj 1232 7 two two CD cord-005646-xhx9pzhj 1232 8 times time NNS cord-005646-xhx9pzhj 1232 9 more more RBR cord-005646-xhx9pzhj 1232 10 frequent frequent JJ cord-005646-xhx9pzhj 1232 11 in in IN cord-005646-xhx9pzhj 1232 12 LA LA NNP cord-005646-xhx9pzhj 1232 13 group group NN cord-005646-xhx9pzhj 1232 14 than than IN cord-005646-xhx9pzhj 1232 15 in in IN cord-005646-xhx9pzhj 1232 16 CA CA NNP cord-005646-xhx9pzhj 1232 17 group group NN cord-005646-xhx9pzhj 1232 18 , , , cord-005646-xhx9pzhj 1232 19 The the DT cord-005646-xhx9pzhj 1232 20 antifungal antifungal JJ cord-005646-xhx9pzhj 1232 21 efficacy efficacy NN cord-005646-xhx9pzhj 1232 22 was be VBD cord-005646-xhx9pzhj 1232 23 62 62 CD cord-005646-xhx9pzhj 1232 24 % % NN cord-005646-xhx9pzhj 1232 25 for for IN cord-005646-xhx9pzhj 1232 26 CA CA NNP cord-005646-xhx9pzhj 1232 27 and and CC cord-005646-xhx9pzhj 1232 28 67 67 CD cord-005646-xhx9pzhj 1232 29 % % NN cord-005646-xhx9pzhj 1232 30 for for IN cord-005646-xhx9pzhj 1232 31 LA LA NNP cord-005646-xhx9pzhj 1232 32 . . . cord-005646-xhx9pzhj 1233 1 Therapeutic therapeutic JJ cord-005646-xhx9pzhj 1233 2 failure failure NN cord-005646-xhx9pzhj 1233 3 or or CC cord-005646-xhx9pzhj 1233 4 toxicity toxicity NN cord-005646-xhx9pzhj 1233 5 induced induce VBN cord-005646-xhx9pzhj 1233 6 withdraw withdraw NN cord-005646-xhx9pzhj 1233 7 of of IN cord-005646-xhx9pzhj 1233 8 CA CA NNP cord-005646-xhx9pzhj 1233 9 in in IN cord-005646-xhx9pzhj 1233 10 7 7 CD cord-005646-xhx9pzhj 1233 11 % % NN cord-005646-xhx9pzhj 1233 12 of of IN cord-005646-xhx9pzhj 1233 13 cases case NNS cord-005646-xhx9pzhj 1233 14 , , , cord-005646-xhx9pzhj 1233 15 vs vs IN cord-005646-xhx9pzhj 1233 16 , , , cord-005646-xhx9pzhj 1233 17 1,5 1,5 CD cord-005646-xhx9pzhj 1233 18 % % NN cord-005646-xhx9pzhj 1233 19 for for IN cord-005646-xhx9pzhj 1233 20 LA LA NNP cord-005646-xhx9pzhj 1233 21 ( ( -LRB- cord-005646-xhx9pzhj 1233 22 p<0,01 p<0,01 NN cord-005646-xhx9pzhj 1233 23 ) ) -RRB- cord-005646-xhx9pzhj 1233 24 . . . cord-005646-xhx9pzhj 1234 1 Mortality mortality NN cord-005646-xhx9pzhj 1234 2 was be VBD cord-005646-xhx9pzhj 1234 3 not not RB cord-005646-xhx9pzhj 1234 4 different different JJ cord-005646-xhx9pzhj 1234 5 in in IN cord-005646-xhx9pzhj 1234 6 both both DT cord-005646-xhx9pzhj 1234 7 groups group NNS cord-005646-xhx9pzhj 1234 8 ( ( -LRB- cord-005646-xhx9pzhj 1234 9 21 21 CD cord-005646-xhx9pzhj 1234 10 vs. vs. IN cord-005646-xhx9pzhj 1234 11 22 22 CD cord-005646-xhx9pzhj 1234 12 % % NN cord-005646-xhx9pzhj 1234 13 ) ) -RRB- cord-005646-xhx9pzhj 1234 14 , , , cord-005646-xhx9pzhj 1234 15 Adverse adverse JJ cord-005646-xhx9pzhj 1234 16 effects effect NNS cord-005646-xhx9pzhj 1234 17 were be VBD cord-005646-xhx9pzhj 1234 18 related relate VBN cord-005646-xhx9pzhj 1234 19 to to IN cord-005646-xhx9pzhj 1234 20 CA CA NNP cord-005646-xhx9pzhj 1234 21 in in IN cord-005646-xhx9pzhj 1234 22 28 28 CD cord-005646-xhx9pzhj 1234 23 events event NNS cord-005646-xhx9pzhj 1234 24 vs vs IN cord-005646-xhx9pzhj 1234 25 , , , cord-005646-xhx9pzhj 1234 26 only only RB cord-005646-xhx9pzhj 1234 27 one one CD cord-005646-xhx9pzhj 1234 28 in in IN cord-005646-xhx9pzhj 1234 29 LA LA NNP cord-005646-xhx9pzhj 1234 30 group group NN cord-005646-xhx9pzhj 1234 31 ( ( -LRB- cord-005646-xhx9pzhj 1234 32 p<0,01 p<0,01 NN cord-005646-xhx9pzhj 1234 33 ) ) -RRB- cord-005646-xhx9pzhj 1234 34 . . . cord-005646-xhx9pzhj 1235 1 The the DT cord-005646-xhx9pzhj 1235 2 commonest common JJS cord-005646-xhx9pzhj 1235 3 side side NN cord-005646-xhx9pzhj 1235 4 effects effect NNS cord-005646-xhx9pzhj 1235 5 in in IN cord-005646-xhx9pzhj 1235 6 CA CA NNP cord-005646-xhx9pzhj 1235 7 patients patient NNS cord-005646-xhx9pzhj 1235 8 were be VBD cord-005646-xhx9pzhj 1235 9 fever fever NN cord-005646-xhx9pzhj 1235 10 ( ( -LRB- cord-005646-xhx9pzhj 1235 11 18 18 CD cord-005646-xhx9pzhj 1235 12 % % NN cord-005646-xhx9pzhj 1235 13 ) ) -RRB- cord-005646-xhx9pzhj 1235 14 , , , cord-005646-xhx9pzhj 1235 15 chilis chilis NNPS cord-005646-xhx9pzhj 1235 16 ( ( -LRB- cord-005646-xhx9pzhj 1235 17 10 10 CD cord-005646-xhx9pzhj 1235 18 % % NN cord-005646-xhx9pzhj 1235 19 ) ) -RRB- cord-005646-xhx9pzhj 1235 20 and and CC cord-005646-xhx9pzhj 1235 21 nausea nausea NN cord-005646-xhx9pzhj 1235 22 ( ( -LRB- cord-005646-xhx9pzhj 1235 23 9 9 CD cord-005646-xhx9pzhj 1235 24 % % NN cord-005646-xhx9pzhj 1235 25 ) ) -RRB- cord-005646-xhx9pzhj 1235 26 . . . cord-005646-xhx9pzhj 1236 1 In in IN cord-005646-xhx9pzhj 1236 2 CA CA NNP cord-005646-xhx9pzhj 1236 3 group group NN cord-005646-xhx9pzhj 1236 4 , , , cord-005646-xhx9pzhj 1236 5 44 44 CD cord-005646-xhx9pzhj 1236 6 cases case NNS cord-005646-xhx9pzhj 1236 7 ( ( -LRB- cord-005646-xhx9pzhj 1236 8 37 37 CD cord-005646-xhx9pzhj 1236 9 % % NN cord-005646-xhx9pzhj 1236 10 ) ) -RRB- cord-005646-xhx9pzhj 1236 11 developped developpe VBN cord-005646-xhx9pzhj 1236 12 analitical analitical NNP cord-005646-xhx9pzhj 1236 13 anormalities anormalitie NNS cord-005646-xhx9pzhj 1236 14 related relate VBN cord-005646-xhx9pzhj 1236 15 with with IN cord-005646-xhx9pzhj 1236 16 amphotericin amphotericin NNS cord-005646-xhx9pzhj 1236 17 , , , cord-005646-xhx9pzhj 1236 18 vs. vs. FW cord-005646-xhx9pzhj 1236 19 10 10 CD cord-005646-xhx9pzhj 1236 20 cases case NNS cord-005646-xhx9pzhj 1236 21 ( ( -LRB- cord-005646-xhx9pzhj 1236 22 15 15 CD cord-005646-xhx9pzhj 1236 23 % % NN cord-005646-xhx9pzhj 1236 24 ) ) -RRB- cord-005646-xhx9pzhj 1236 25 in in IN cord-005646-xhx9pzhj 1236 26 LA LA NNP cord-005646-xhx9pzhj 1236 27 patients patient NNS cord-005646-xhx9pzhj 1236 28 ( ( -LRB- cord-005646-xhx9pzhj 1236 29 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 1236 30 ) ) -RRB- cord-005646-xhx9pzhj 1236 31 . . . cord-005646-xhx9pzhj 1237 1 In in IN cord-005646-xhx9pzhj 1237 2 the the DT cord-005646-xhx9pzhj 1237 3 first first JJ cord-005646-xhx9pzhj 1237 4 group group NN cord-005646-xhx9pzhj 1237 5 , , , cord-005646-xhx9pzhj 1237 6 the the DT cord-005646-xhx9pzhj 1237 7 commonest common JJS cord-005646-xhx9pzhj 1237 8 serum serum NN cord-005646-xhx9pzhj 1237 9 alterations alteration NNS cord-005646-xhx9pzhj 1237 10 were be VBD cord-005646-xhx9pzhj 1237 11 hypokaliemia hypokaliemia NN cord-005646-xhx9pzhj 1237 12 ( ( -LRB- cord-005646-xhx9pzhj 1237 13 25 25 CD cord-005646-xhx9pzhj 1237 14 % % NN cord-005646-xhx9pzhj 1237 15 ) ) -RRB- cord-005646-xhx9pzhj 1237 16 , , , cord-005646-xhx9pzhj 1237 17 raised raise VBN cord-005646-xhx9pzhj 1237 18 creatinine creatinine NN cord-005646-xhx9pzhj 1237 19 ( ( -LRB- cord-005646-xhx9pzhj 1237 20 14 14 CD cord-005646-xhx9pzhj 1237 21 % % NN cord-005646-xhx9pzhj 1237 22 ) ) -RRB- cord-005646-xhx9pzhj 1237 23 and and CC cord-005646-xhx9pzhj 1237 24 bilirrubin bilirrubin NNP cord-005646-xhx9pzhj 1237 25 ( ( -LRB- cord-005646-xhx9pzhj 1237 26 6 6 CD cord-005646-xhx9pzhj 1237 27 % % NN cord-005646-xhx9pzhj 1237 28 ) ) -RRB- cord-005646-xhx9pzhj 1237 29 . . . cord-005646-xhx9pzhj 1238 1 In in IN cord-005646-xhx9pzhj 1238 2 the the DT cord-005646-xhx9pzhj 1238 3 second second JJ cord-005646-xhx9pzhj 1238 4 one one NN cord-005646-xhx9pzhj 1238 5 , , , cord-005646-xhx9pzhj 1238 6 hypokaliemia hypokaliemia NNP cord-005646-xhx9pzhj 1238 7 presented present VBN cord-005646-xhx9pzhj 1238 8 in in IN cord-005646-xhx9pzhj 1238 9 7 7 CD cord-005646-xhx9pzhj 1238 10 % % NN cord-005646-xhx9pzhj 1238 11 of of IN cord-005646-xhx9pzhj 1238 12 cases case NNS cord-005646-xhx9pzhj 1238 13 ( ( -LRB- cord-005646-xhx9pzhj 1238 14 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 1238 15 ) ) -RRB- cord-005646-xhx9pzhj 1238 16 , , , cord-005646-xhx9pzhj 1238 17 raised raise VBN cord-005646-xhx9pzhj 1238 18 bilirrubin bilirrubin NN cord-005646-xhx9pzhj 1238 19 in in IN cord-005646-xhx9pzhj 1238 20 6 6 CD cord-005646-xhx9pzhj 1238 21 % % NN cord-005646-xhx9pzhj 1238 22 and and CC cord-005646-xhx9pzhj 1238 23 creatinine creatinine NN cord-005646-xhx9pzhj 1238 24 in in IN cord-005646-xhx9pzhj 1238 25 3 3 CD cord-005646-xhx9pzhj 1238 26 % % NN cord-005646-xhx9pzhj 1238 27 ( ( -LRB- cord-005646-xhx9pzhj 1238 28 p<0,05 p<0,05 NNP cord-005646-xhx9pzhj 1238 29 ) ) -RRB- cord-005646-xhx9pzhj 1238 30 , , , cord-005646-xhx9pzhj 1238 31 The the DT cord-005646-xhx9pzhj 1238 32 antifungal antifungal JJ cord-005646-xhx9pzhj 1238 33 efficacy efficacy NN cord-005646-xhx9pzhj 1238 34 of of IN cord-005646-xhx9pzhj 1238 35 LA LA NNP cord-005646-xhx9pzhj 1238 36 is be VBZ cord-005646-xhx9pzhj 1238 37 at at IN cord-005646-xhx9pzhj 1238 38 least least JJS cord-005646-xhx9pzhj 1238 39 the the DT cord-005646-xhx9pzhj 1238 40 same same JJ cord-005646-xhx9pzhj 1238 41 of of IN cord-005646-xhx9pzhj 1238 42 CA CA NNP cord-005646-xhx9pzhj 1238 43 . . . cord-005646-xhx9pzhj 1239 1 From from IN cord-005646-xhx9pzhj 1239 2 the the DT cord-005646-xhx9pzhj 1239 3 clinical clinical JJ cord-005646-xhx9pzhj 1239 4 and and CC cord-005646-xhx9pzhj 1239 5 analitical analitical JJ cord-005646-xhx9pzhj 1239 6 points point NNS cord-005646-xhx9pzhj 1239 7 of of IN cord-005646-xhx9pzhj 1239 8 view view NN cord-005646-xhx9pzhj 1239 9 , , , cord-005646-xhx9pzhj 1239 10 LA LA NNP cord-005646-xhx9pzhj 1239 11 is be VBZ cord-005646-xhx9pzhj 1239 12 much much RB cord-005646-xhx9pzhj 1239 13 less less RBR cord-005646-xhx9pzhj 1239 14 toxic toxic JJ cord-005646-xhx9pzhj 1239 15 than than IN cord-005646-xhx9pzhj 1239 16 CA CA NNP cord-005646-xhx9pzhj 1239 17 . . . cord-005646-xhx9pzhj 1240 1 LA LA NNP cord-005646-xhx9pzhj 1240 2 can can MD cord-005646-xhx9pzhj 1240 3 be be VB cord-005646-xhx9pzhj 1240 4 used use VBN cord-005646-xhx9pzhj 1240 5 at at IN cord-005646-xhx9pzhj 1240 6 a a DT cord-005646-xhx9pzhj 1240 7 greater great JJR cord-005646-xhx9pzhj 1240 8 dose dose NN cord-005646-xhx9pzhj 1240 9 than than IN cord-005646-xhx9pzhj 1240 10 CA CA NNP cord-005646-xhx9pzhj 1240 11 and and CC cord-005646-xhx9pzhj 1240 12 is be VBZ cord-005646-xhx9pzhj 1240 13 safe safe JJ cord-005646-xhx9pzhj 1240 14 in in IN cord-005646-xhx9pzhj 1240 15 children child NNS cord-005646-xhx9pzhj 1240 16 with with IN cord-005646-xhx9pzhj 1240 17 renal renal JJ cord-005646-xhx9pzhj 1240 18 failure failure NN cord-005646-xhx9pzhj 1240 19 . . . cord-005646-xhx9pzhj 1241 1 Laurence Laurence NNP cord-005646-xhx9pzhj 1241 2 DESPLANQUES DESPLANQUES NNP cord-005646-xhx9pzhj 1241 3 -Serge -serge RB cord-005646-xhx9pzhj 1242 1 GOTTOT GOTTOT NNP cord-005646-xhx9pzhj 1243 1 -Christian -Christian NNP cord-005646-xhx9pzhj 1244 1 DAGEVILLE DAGEVILLE NNP cord-005646-xhx9pzhj 1244 2 D D NNP cord-005646-xhx9pzhj 1244 3 ~ ~ NFP cord-005646-xhx9pzhj 1244 4 artement artement NNP cord-005646-xhx9pzhj 1244 5 de de NNP cord-005646-xhx9pzhj 1244 6 Sant~ Sant~ NNP cord-005646-xhx9pzhj 1244 7 Publique Publique NNP cord-005646-xhx9pzhj 1244 8 -Facult~ -Facult~ VBZ cord-005646-xhx9pzhj 1244 9 Xavier Xavier NNP cord-005646-xhx9pzhj 1244 10 Bichat Bichat NNP cord-005646-xhx9pzhj 1245 1 -16 -16 FW cord-005646-xhx9pzhj 1245 2 rue rue FW cord-005646-xhx9pzhj 1245 3 Henri Henri NNP cord-005646-xhx9pzhj 1245 4 Huchard Huchard NNP cord-005646-xhx9pzhj 1246 1 75018 75018 CD cord-005646-xhx9pzhj 1246 2 Paris Paris NNP cord-005646-xhx9pzhj 1247 1 -France -france RB cord-005646-xhx9pzhj 1247 2 -The -The : cord-005646-xhx9pzhj 1247 3 French french JJ cord-005646-xhx9pzhj 1247 4 < < XX cord-005646-xhx9pzhj 1247 5 < < XX cord-005646-xhx9pzhj 1247 6 Reaped reap VBD cord-005646-xhx9pzhj 1247 7 ~ ~ NFP cord-005646-xhx9pzhj 1247 8 > > XX cord-005646-xhx9pzhj 1248 1 network network NN cord-005646-xhx9pzhj 1248 2 was be VBD cord-005646-xhx9pzhj 1248 3 created create VBN cord-005646-xhx9pzhj 1248 4 to to TO cord-005646-xhx9pzhj 1248 5 implement implement VB cord-005646-xhx9pzhj 1248 6 a a DT cord-005646-xhx9pzhj 1248 7 nosecomial nosecomial JJ cord-005646-xhx9pzhj 1248 8 infections infection NNS cord-005646-xhx9pzhj 1248 9 ( ( -LRB- cord-005646-xhx9pzhj 1248 10 NI NI NNP cord-005646-xhx9pzhj 1248 11 ) ) -RRB- cord-005646-xhx9pzhj 1248 12 quality quality NN cord-005646-xhx9pzhj 1248 13 care care NN cord-005646-xhx9pzhj 1248 14 program program NN cord-005646-xhx9pzhj 1248 15 in in IN cord-005646-xhx9pzhj 1248 16 NICU NICU NNP cord-005646-xhx9pzhj 1248 17 and and CC cord-005646-xhx9pzhj 1248 18 PICU PICU NNP cord-005646-xhx9pzhj 1248 19 , , , cord-005646-xhx9pzhj 1248 20 The the DT cord-005646-xhx9pzhj 1248 21 first first JJ cord-005646-xhx9pzhj 1248 22 objective objective NN cord-005646-xhx9pzhj 1248 23 was be VBD cord-005646-xhx9pzhj 1248 24 to to TO cord-005646-xhx9pzhj 1248 25 describe describe VB cord-005646-xhx9pzhj 1248 26 the the DT cord-005646-xhx9pzhj 1248 27 annual annual JJ cord-005646-xhx9pzhj 1248 28 NI NI NNP cord-005646-xhx9pzhj 1248 29 incidence incidence NN cord-005646-xhx9pzhj 1248 30 rate rate NN cord-005646-xhx9pzhj 1248 31 in in IN cord-005646-xhx9pzhj 1248 32 each each DT cord-005646-xhx9pzhj 1248 33 ICU ICU NNP cord-005646-xhx9pzhj 1248 34 population population NN cord-005646-xhx9pzhj 1248 35 : : : cord-005646-xhx9pzhj 1248 36 all all DT cord-005646-xhx9pzhj 1248 37 patients patient NNS cord-005646-xhx9pzhj 1248 38 stayed stay VBD cord-005646-xhx9pzhj 1248 39 more more JJR cord-005646-xhx9pzhj 1248 40 than than IN cord-005646-xhx9pzhj 1248 41 48 48 CD cord-005646-xhx9pzhj 1248 42 hours hour NNS cord-005646-xhx9pzhj 1248 43 in in IN cord-005646-xhx9pzhj 1248 44 ICU ICU NNP cord-005646-xhx9pzhj 1248 45 . . . cord-005646-xhx9pzhj 1249 1 Methods method NNS cord-005646-xhx9pzhj 1249 2 : : : cord-005646-xhx9pzhj 1250 1 N n LS cord-005646-xhx9pzhj 1250 2 ] ] -RRB- cord-005646-xhx9pzhj 1250 3 criteria criterion NNS cord-005646-xhx9pzhj 1250 4 were be VBD cord-005646-xhx9pzhj 1250 5 defined define VBN cord-005646-xhx9pzhj 1250 6 by by IN cord-005646-xhx9pzhj 1250 7 the the DT cord-005646-xhx9pzhj 1250 8 Reaped reap VBN cord-005646-xhx9pzhj 1250 9 group group NN cord-005646-xhx9pzhj 1250 10 according accord VBG cord-005646-xhx9pzhj 1250 11 to to IN cord-005646-xhx9pzhj 1250 12 CDC CDC NNP cord-005646-xhx9pzhj 1250 13 criteria criterion NNS cord-005646-xhx9pzhj 1250 14 . . . cord-005646-xhx9pzhj 1251 1 All all DT cord-005646-xhx9pzhj 1251 2 data datum NNS cord-005646-xhx9pzhj 1251 3 were be VBD cord-005646-xhx9pzhj 1251 4 collected collect VBN cord-005646-xhx9pzhj 1251 5 by by IN cord-005646-xhx9pzhj 1251 6 a a DT cord-005646-xhx9pzhj 1251 7 medical medical JJ cord-005646-xhx9pzhj 1251 8 and and CC cord-005646-xhx9pzhj 1251 9 nursing nursing NN cord-005646-xhx9pzhj 1251 10 team team NN cord-005646-xhx9pzhj 1251 11 . . . cord-005646-xhx9pzhj 1252 1 All all DT cord-005646-xhx9pzhj 1252 2 infection infection NN cord-005646-xhx9pzhj 1252 3 data datum NNS cord-005646-xhx9pzhj 1252 4 were be VBD cord-005646-xhx9pzhj 1252 5 validated validate VBN cord-005646-xhx9pzhj 1252 6 by by IN cord-005646-xhx9pzhj 1252 7 an an DT cord-005646-xhx9pzhj 1252 8 external external JJ cord-005646-xhx9pzhj 1252 9 investigator investigator NN cord-005646-xhx9pzhj 1252 10 . . . cord-005646-xhx9pzhj 1253 1 Results result NNS cord-005646-xhx9pzhj 1253 2 : : : cord-005646-xhx9pzhj 1254 1 4525 4525 CD cord-005646-xhx9pzhj 1254 2 patients patient NNS cord-005646-xhx9pzhj 1254 3 were be VBD cord-005646-xhx9pzhj 1254 4 admitted admit VBN cord-005646-xhx9pzhj 1254 5 over over IN cord-005646-xhx9pzhj 1254 6 a a DT cord-005646-xhx9pzhj 1254 7 14 14 CD cord-005646-xhx9pzhj 1254 8 months month NNS cord-005646-xhx9pzhj 1254 9 period period NN cord-005646-xhx9pzhj 1254 10 . . . cord-005646-xhx9pzhj 1255 1 68 68 CD cord-005646-xhx9pzhj 1255 2 % % NN cord-005646-xhx9pzhj 1255 3 were be VBD cord-005646-xhx9pzhj 1255 4 newborns newborn NNS cord-005646-xhx9pzhj 1255 5 . . . cord-005646-xhx9pzhj 1256 1 371 371 CD cord-005646-xhx9pzhj 1256 2 NI NI NNP cord-005646-xhx9pzhj 1256 3 were be VBD cord-005646-xhx9pzhj 1256 4 identified identify VBN cord-005646-xhx9pzhj 1256 5 among among IN cord-005646-xhx9pzhj 1256 6 311 311 CD cord-005646-xhx9pzhj 1256 7 patients patient NNS cord-005646-xhx9pzhj 1256 8 . . . cord-005646-xhx9pzhj 1257 1 The the DT cord-005646-xhx9pzhj 1257 2 overall overall JJ cord-005646-xhx9pzhj 1257 3 NI NI NNP cord-005646-xhx9pzhj 1257 4 incidence incidence NN cord-005646-xhx9pzhj 1257 5 rate rate NN cord-005646-xhx9pzhj 1257 6 ( ( -LRB- cord-005646-xhx9pzhj 1257 7 IR IR NNP cord-005646-xhx9pzhj 1257 8 ) ) -RRB- cord-005646-xhx9pzhj 1257 9 was be VBD cord-005646-xhx9pzhj 1257 10 8.2 8.2 CD cord-005646-xhx9pzhj 1257 11 % % NN cord-005646-xhx9pzhj 1257 12 and and CC cord-005646-xhx9pzhj 1257 13 5.9 5.9 CD cord-005646-xhx9pzhj 1257 14 ° ° NN cord-005646-xhx9pzhj 1257 15 /00 /00 JJ cord-005646-xhx9pzhj 1257 16 person person NN cord-005646-xhx9pzhj 1257 17 day day NN cord-005646-xhx9pzhj 1257 18 ( ( -LRB- cord-005646-xhx9pzhj 1257 19 from from IN cord-005646-xhx9pzhj 1257 20 5.0 5.0 CD cord-005646-xhx9pzhj 1257 21 to to TO cord-005646-xhx9pzhj 1257 22 8.2 8.2 CD cord-005646-xhx9pzhj 1257 23 ° ° NN cord-005646-xhx9pzhj 1257 24 /00 /00 NN cord-005646-xhx9pzhj 1257 25 according accord VBG cord-005646-xhx9pzhj 1257 26 to to IN cord-005646-xhx9pzhj 1257 27 age age NN cord-005646-xhx9pzhj 1257 28 , , , cord-005646-xhx9pzhj 1257 29 lowest low JJS cord-005646-xhx9pzhj 1257 30 rate rate NN cord-005646-xhx9pzhj 1257 31 for for IN cord-005646-xhx9pzhj 1257 32 newborns newborn NNS cord-005646-xhx9pzhj 1257 33 ) ) -RRB- cord-005646-xhx9pzhj 1257 34 . . . cord-005646-xhx9pzhj 1258 1 Septicemia septicemia NN cord-005646-xhx9pzhj 1258 2 ( ( -LRB- cord-005646-xhx9pzhj 1258 3 50 50 CD cord-005646-xhx9pzhj 1258 4 % % NN cord-005646-xhx9pzhj 1258 5 of of IN cord-005646-xhx9pzhj 1258 6 NI NI NNP cord-005646-xhx9pzhj 1258 7 ) ) -RRB- cord-005646-xhx9pzhj 1258 8 and and CC cord-005646-xhx9pzhj 1258 9 pneumonia pneumonia NN cord-005646-xhx9pzhj 1258 10 ( ( -LRB- cord-005646-xhx9pzhj 1258 11 41 41 CD cord-005646-xhx9pzhj 1258 12 % % NN cord-005646-xhx9pzhj 1258 13 of of IN cord-005646-xhx9pzhj 1258 14 NI NI NNP cord-005646-xhx9pzhj 1258 15 ) ) -RRB- cord-005646-xhx9pzhj 1258 16 were be VBD cord-005646-xhx9pzhj 1258 17 the the DT cord-005646-xhx9pzhj 1258 18 two two CD cord-005646-xhx9pzhj 1258 19 main main JJ cord-005646-xhx9pzhj 1258 20 NI NI NNP cord-005646-xhx9pzhj 1258 21 . . . cord-005646-xhx9pzhj 1259 1 According accord VBG cord-005646-xhx9pzhj 1259 2 to to IN cord-005646-xhx9pzhj 1259 3 age age NN cord-005646-xhx9pzhj 1259 4 , , , cord-005646-xhx9pzhj 1259 5 the the DT cord-005646-xhx9pzhj 1259 6 septicemia septicemia NN cord-005646-xhx9pzhj 1259 7 IR IR NNP cord-005646-xhx9pzhj 1259 8 varied vary VBD cord-005646-xhx9pzhj 1259 9 from from IN cord-005646-xhx9pzhj 1259 10 6.8 6.8 CD cord-005646-xhx9pzhj 1259 11 to to IN cord-005646-xhx9pzhj 1259 12 10.9 10.9 CD cord-005646-xhx9pzhj 1259 13 ° ° NN cord-005646-xhx9pzhj 1259 14 /oo /oo . cord-005646-xhx9pzhj 1259 15 catheter catheter NNP cord-005646-xhx9pzhj 1259 16 day day NN cord-005646-xhx9pzhj 1259 17 ( ( -LRB- cord-005646-xhx9pzhj 1259 18 lowest low JJS cord-005646-xhx9pzhj 1259 19 rate rate NN cord-005646-xhx9pzhj 1259 20 for for IN cord-005646-xhx9pzhj 1259 21 newborns newborn NNS cord-005646-xhx9pzhj 1259 22 ) ) -RRB- cord-005646-xhx9pzhj 1259 23 and and CC cord-005646-xhx9pzhj 1259 24 the the DT cord-005646-xhx9pzhj 1259 25 pneumonia pneumonia NN cord-005646-xhx9pzhj 1259 26 IR IR NNP cord-005646-xhx9pzhj 1259 27 from from IN cord-005646-xhx9pzhj 1259 28 3.9 3.9 CD cord-005646-xhx9pzhj 1259 29 to to IN cord-005646-xhx9pzhj 1259 30 7.4 7.4 CD cord-005646-xhx9pzhj 1259 31 ° ° NN cord-005646-xhx9pzhj 1259 32 /00 /00 NNP cord-005646-xhx9pzhj 1259 33 ventilator ventilator NNP cord-005646-xhx9pzhj 1259 34 day day NNP cord-005646-xhx9pzhj 1259 35 ( ( -LRB- cord-005646-xhx9pzhj 1259 36 lowest low JJS cord-005646-xhx9pzhj 1259 37 rate rate NN cord-005646-xhx9pzhj 1259 38 for for IN cord-005646-xhx9pzhj 1259 39 newborns newborn NNS cord-005646-xhx9pzhj 1259 40 ) ) -RRB- cord-005646-xhx9pzhj 1259 41 . . . cord-005646-xhx9pzhj 1260 1 There there EX cord-005646-xhx9pzhj 1260 2 were be VBD cord-005646-xhx9pzhj 1260 3 very very RB cord-005646-xhx9pzhj 1260 4 few few JJ cord-005646-xhx9pzhj 1260 5 other other JJ cord-005646-xhx9pzhj 1260 6 infections infection NNS cord-005646-xhx9pzhj 1260 7 ( ( -LRB- cord-005646-xhx9pzhj 1260 8 UTI UTI NNP cord-005646-xhx9pzhj 1260 9 : : : cord-005646-xhx9pzhj 1260 10 4 4 CD cord-005646-xhx9pzhj 1260 11 % % NN cord-005646-xhx9pzhj 1260 12 , , , cord-005646-xhx9pzhj 1260 13 IR IR NNP cord-005646-xhx9pzhj 1260 14 : : : cord-005646-xhx9pzhj 1260 15 7.4 7.4 CD cord-005646-xhx9pzhj 1260 16 ° ° NN cord-005646-xhx9pzhj 1260 17 /00 /00 JJ cord-005646-xhx9pzhj 1260 18 catheter catheter NN cord-005646-xhx9pzhj 1260 19 day day NN cord-005646-xhx9pzhj 1260 20 ) ) -RRB- cord-005646-xhx9pzhj 1260 21 . . . cord-005646-xhx9pzhj 1261 1 Gram gram NN cord-005646-xhx9pzhj 1261 2 positive positive JJ cord-005646-xhx9pzhj 1261 3 cocci coccus NNS cord-005646-xhx9pzhj 1261 4 were be VBD cord-005646-xhx9pzhj 1261 5 isolated isolate VBN cord-005646-xhx9pzhj 1261 6 in in IN cord-005646-xhx9pzhj 1261 7 73 73 CD cord-005646-xhx9pzhj 1261 8 % % NN cord-005646-xhx9pzhj 1261 9 of of IN cord-005646-xhx9pzhj 1261 10 septicemia septicemia NN cord-005646-xhx9pzhj 1261 11 ( ( -LRB- cord-005646-xhx9pzhj 1261 12 70 70 CD cord-005646-xhx9pzhj 1261 13 % % NN cord-005646-xhx9pzhj 1261 14 of of IN cord-005646-xhx9pzhj 1261 15 them -PRON- PRP cord-005646-xhx9pzhj 1261 16 were be VBD cord-005646-xhx9pzhj 1261 17 coagulase coagulase JJ cord-005646-xhx9pzhj 1261 18 negative negative JJ cord-005646-xhx9pzhj 1261 19 staphylococcal staphylococcal NN cord-005646-xhx9pzhj 1261 20 ) ) -RRB- cord-005646-xhx9pzhj 1261 21 . . . cord-005646-xhx9pzhj 1262 1 Gram gram NN cord-005646-xhx9pzhj 1262 2 negative negative JJ cord-005646-xhx9pzhj 1262 3 bacilli bacilli NN cord-005646-xhx9pzhj 1262 4 were be VBD cord-005646-xhx9pzhj 1262 5 isolated isolate VBN cord-005646-xhx9pzhj 1262 6 in in IN cord-005646-xhx9pzhj 1262 7 53 53 CD cord-005646-xhx9pzhj 1262 8 % % NN cord-005646-xhx9pzhj 1262 9 of of IN cord-005646-xhx9pzhj 1262 10 pneumonia pneumonia NN cord-005646-xhx9pzhj 1262 11 ( ( -LRB- cord-005646-xhx9pzhj 1262 12 40 40 CD cord-005646-xhx9pzhj 1262 13 % % NN cord-005646-xhx9pzhj 1262 14 of of IN cord-005646-xhx9pzhj 1262 15 them -PRON- PRP cord-005646-xhx9pzhj 1262 16 were be VBD cord-005646-xhx9pzhj 1262 17 pseudomonas pseudomonas NN cord-005646-xhx9pzhj 1262 18 ) ) -RRB- cord-005646-xhx9pzhj 1262 19 . . . cord-005646-xhx9pzhj 1263 1 5 5 CD cord-005646-xhx9pzhj 1263 2 % % NN cord-005646-xhx9pzhj 1263 3 of of IN cord-005646-xhx9pzhj 1263 4 NI NI NNP cord-005646-xhx9pzhj 1263 5 were be VBD cord-005646-xhx9pzhj 1263 6 caused cause VBN cord-005646-xhx9pzhj 1263 7 by by IN cord-005646-xhx9pzhj 1263 8 candida candida NN cord-005646-xhx9pzhj 1263 9 , , , cord-005646-xhx9pzhj 1263 10 mostly mostly RB cord-005646-xhx9pzhj 1263 11 septicemia septicemia NN cord-005646-xhx9pzhj 1263 12 . . . cord-005646-xhx9pzhj 1264 1 The the DT cord-005646-xhx9pzhj 1264 2 septicemia septicemia NN cord-005646-xhx9pzhj 1264 3 and and CC cord-005646-xhx9pzhj 1264 4 pneumonia pneumonia NN cord-005646-xhx9pzhj 1264 5 IR IR NNP cord-005646-xhx9pzhj 1264 6 varied vary VBD cord-005646-xhx9pzhj 1264 7 according accord VBG cord-005646-xhx9pzhj 1264 8 to to IN cord-005646-xhx9pzhj 1264 9 unit unit NN cord-005646-xhx9pzhj 1264 10 even even RB cord-005646-xhx9pzhj 1264 11 after after IN cord-005646-xhx9pzhj 1264 12 adjustment adjustment NN cord-005646-xhx9pzhj 1264 13 for for IN cord-005646-xhx9pzhj 1264 14 age age NN cord-005646-xhx9pzhj 1264 15 . . . cord-005646-xhx9pzhj 1265 1 Discussion discussion NN cord-005646-xhx9pzhj 1265 2 _SP cord-005646-xhx9pzhj 1266 1 The the DT cord-005646-xhx9pzhj 1266 2 aminoglycoside aminoglycoside JJ cord-005646-xhx9pzhj 1266 3 antibiotics antibiotic NNS cord-005646-xhx9pzhj 1266 4 are be VBP cord-005646-xhx9pzhj 1266 5 frequently frequently RB cord-005646-xhx9pzhj 1266 6 used use VBN cord-005646-xhx9pzhj 1266 7 in in IN cord-005646-xhx9pzhj 1266 8 newborns newborn NNS cord-005646-xhx9pzhj 1266 9 for for IN cord-005646-xhx9pzhj 1266 10 the the DT cord-005646-xhx9pzhj 1266 11 treatment treatment NN cord-005646-xhx9pzhj 1266 12 of of IN cord-005646-xhx9pzhj 1266 13 severe severe JJ cord-005646-xhx9pzhj 1266 14 infection infection NN cord-005646-xhx9pzhj 1266 15 and and CC cord-005646-xhx9pzhj 1266 16 sepsis sepsis NN cord-005646-xhx9pzhj 1266 17 due due IN cord-005646-xhx9pzhj 1266 18 to to IN cord-005646-xhx9pzhj 1266 19 Gram gram NN cord-005646-xhx9pzhj 1266 20 - - HYPH cord-005646-xhx9pzhj 1266 21 negative negative JJ cord-005646-xhx9pzhj 1266 22 microorganisms microorganism NNS cord-005646-xhx9pzhj 1266 23 . . . cord-005646-xhx9pzhj 1267 1 The the DT cord-005646-xhx9pzhj 1267 2 currently currently RB cord-005646-xhx9pzhj 1267 3 recommended recommend VBN cord-005646-xhx9pzhj 1267 4 dosage dosage NN cord-005646-xhx9pzhj 1267 5 schedule schedule NN cord-005646-xhx9pzhj 1267 6 for for IN cord-005646-xhx9pzhj 1267 7 TOBRA TOBRA NNP cord-005646-xhx9pzhj 1268 1 ( ( -LRB- cord-005646-xhx9pzhj 1268 2 2.5 2.5 CD cord-005646-xhx9pzhj 1268 3 mg mg NNP cord-005646-xhx9pzhj 1268 4 / / SYM cord-005646-xhx9pzhj 1268 5 kg kg NNP cord-005646-xhx9pzhj 1269 1 q18h q18h LS cord-005646-xhx9pzhj 1269 2 ) ) -RRB- cord-005646-xhx9pzhj 1269 3 does do VBZ cord-005646-xhx9pzhj 1269 4 not not RB cord-005646-xhx9pzhj 1269 5 take take VB cord-005646-xhx9pzhj 1269 6 into into IN cord-005646-xhx9pzhj 1269 7 account account NN cord-005646-xhx9pzhj 1269 8 differences difference NNS cord-005646-xhx9pzhj 1269 9 in in IN cord-005646-xhx9pzhj 1269 10 gestational gestational JJ cord-005646-xhx9pzhj 1269 11 or or CC cord-005646-xhx9pzhj 1269 12 postnatal postnatal JJ cord-005646-xhx9pzhj 1269 13 age age NN cord-005646-xhx9pzhj 1269 14 during during IN cord-005646-xhx9pzhj 1269 15 the the DT cord-005646-xhx9pzhj 1269 16 first first JJ cord-005646-xhx9pzhj 1269 17 4 4 CD cord-005646-xhx9pzhj 1269 18 weeks week NNS cord-005646-xhx9pzhj 1269 19 of of IN cord-005646-xhx9pzhj 1269 20 life life NN cord-005646-xhx9pzhj 1269 21 . . . cord-005646-xhx9pzhj 1270 1 We -PRON- PRP cord-005646-xhx9pzhj 1270 2 questioned question VBD cord-005646-xhx9pzhj 1270 3 the the DT cord-005646-xhx9pzhj 1270 4 validity validity NN cord-005646-xhx9pzhj 1270 5 of of IN cord-005646-xhx9pzhj 1270 6 these these DT cord-005646-xhx9pzhj 1270 7 recommendations recommendation NNS cord-005646-xhx9pzhj 1270 8 and and CC cord-005646-xhx9pzhj 1270 9 studied study VBD cord-005646-xhx9pzhj 1270 10 the the DT cord-005646-xhx9pzhj 1270 11 population population NN cord-005646-xhx9pzhj 1270 12 kinetics kinetics NN cord-005646-xhx9pzhj 1270 13 of of IN cord-005646-xhx9pzhj 1270 14 tobramycin tobramycin NNS cord-005646-xhx9pzhj 1270 15 to to TO cord-005646-xhx9pzhj 1270 16 establish establish VB cord-005646-xhx9pzhj 1270 17 predictive predictive JJ cord-005646-xhx9pzhj 1270 18 equations equation NNS cord-005646-xhx9pzhj 1270 19 that that WDT cord-005646-xhx9pzhj 1270 20 enables enable VBZ cord-005646-xhx9pzhj 1270 21 the the DT cord-005646-xhx9pzhj 1270 22 clinician clinician NN cord-005646-xhx9pzhj 1270 23 to to TO cord-005646-xhx9pzhj 1270 24 select select VB cord-005646-xhx9pzhj 1270 25 the the DT cord-005646-xhx9pzhj 1270 26 appropriate appropriate JJ cord-005646-xhx9pzhj 1270 27 initial initial JJ cord-005646-xhx9pzhj 1270 28 dosing dosing NN cord-005646-xhx9pzhj 1270 29 schedule schedule NN cord-005646-xhx9pzhj 1270 30 . . . cord-005646-xhx9pzhj 1271 1 Methods method NNS cord-005646-xhx9pzhj 1271 2 TOBRA TOBRA NNP cord-005646-xhx9pzhj 1271 3 trough trough NN cord-005646-xhx9pzhj 1271 4 ( ( -LRB- cord-005646-xhx9pzhj 1271 5 t=0 t=0 NNS cord-005646-xhx9pzhj 1271 6 ) ) -RRB- cord-005646-xhx9pzhj 1271 7 and and CC cord-005646-xhx9pzhj 1271 8 peak peak NN cord-005646-xhx9pzhj 1271 9 values value NNS cord-005646-xhx9pzhj 1271 10 ( ( -LRB- cord-005646-xhx9pzhj 1271 11 t= t= NN cord-005646-xhx9pzhj 1271 12 1 1 CD cord-005646-xhx9pzhj 1271 13 ) ) -RRB- cord-005646-xhx9pzhj 1271 14 were be VBD cord-005646-xhx9pzhj 1271 15 taken take VBN cord-005646-xhx9pzhj 1271 16 on on IN cord-005646-xhx9pzhj 1271 17 day day NN cord-005646-xhx9pzhj 1271 18 2 2 CD cord-005646-xhx9pzhj 1271 19 - - SYM cord-005646-xhx9pzhj 1271 20 4 4 CD cord-005646-xhx9pzhj 1271 21 after after IN cord-005646-xhx9pzhj 1271 22 birth birth NN cord-005646-xhx9pzhj 1271 23 in in IN cord-005646-xhx9pzhj 1271 24 460 460 CD cord-005646-xhx9pzhj 1271 25 newborns newborn NNS cord-005646-xhx9pzhj 1271 26 . . . cord-005646-xhx9pzhj 1272 1 TOBRA TOBRA NNP cord-005646-xhx9pzhj 1272 2 was be VBD cord-005646-xhx9pzhj 1272 3 administered administer VBN cord-005646-xhx9pzhj 1272 4 as as IN cord-005646-xhx9pzhj 1272 5 a a DT cord-005646-xhx9pzhj 1272 6 30-minute 30-minute JJ cord-005646-xhx9pzhj 1272 7 intravenous intravenous JJ cord-005646-xhx9pzhj 1272 8 infusion infusion NN cord-005646-xhx9pzhj 1272 9 already already RB cord-005646-xhx9pzhj 1272 10 in in IN cord-005646-xhx9pzhj 1272 11 an an DT cord-005646-xhx9pzhj 1272 12 adapted adapt VBN cord-005646-xhx9pzhj 1272 13 dosage dosage NN cord-005646-xhx9pzhj 1272 14 schedule schedule NN cord-005646-xhx9pzhj 1272 15 : : : cord-005646-xhx9pzhj 1273 1 3.5 3.5 CD cord-005646-xhx9pzhj 1273 2 mg mg NNP cord-005646-xhx9pzhj 1273 3 / / SYM cord-005646-xhx9pzhj 1273 4 kg kg NNP cord-005646-xhx9pzhj 1273 5 q24h q24h CD cord-005646-xhx9pzhj 1274 1 in in IN cord-005646-xhx9pzhj 1274 2 infants infant NNS cord-005646-xhx9pzhj 1274 3 with with IN cord-005646-xhx9pzhj 1274 4 GAs gas NNS cord-005646-xhx9pzhj 1274 5 < < XX cord-005646-xhx9pzhj 1274 6 28 28 CD cord-005646-xhx9pzhj 1274 7 weeks week NNS cord-005646-xhx9pzhj 1275 1 ; ; : cord-005646-xhx9pzhj 1275 2 2.5 2.5 CD cord-005646-xhx9pzhj 1275 3 mg mg NNP cord-005646-xhx9pzhj 1275 4 / / SYM cord-005646-xhx9pzhj 1275 5 kg kg NNP cord-005646-xhx9pzhj 1275 6 q18h q18h : cord-005646-xhx9pzhj 1275 7 in in IN cord-005646-xhx9pzhj 1275 8 infants infant NNS cord-005646-xhx9pzhj 1275 9 with with IN cord-005646-xhx9pzhj 1275 10 GAs gas NNS cord-005646-xhx9pzhj 1275 11 between between IN cord-005646-xhx9pzhj 1275 12 28 28 CD cord-005646-xhx9pzhj 1275 13 - - SYM cord-005646-xhx9pzhj 1275 14 36 36 CD cord-005646-xhx9pzhj 1275 15 weeks week NNS cord-005646-xhx9pzhj 1275 16 and and CC cord-005646-xhx9pzhj 1275 17 2.5 2.5 CD cord-005646-xhx9pzhj 1275 18 mg mg NNP cord-005646-xhx9pzhj 1275 19 / / SYM cord-005646-xhx9pzhj 1275 20 kg kg NNP cord-005646-xhx9pzhj 1275 21 q12h q12h CD cord-005646-xhx9pzhj 1275 22 in in IN cord-005646-xhx9pzhj 1275 23 infants infant NNS cord-005646-xhx9pzhj 1275 24 with with IN cord-005646-xhx9pzhj 1275 25 GAs gas NNS cord-005646-xhx9pzhj 1275 26 > > XX cord-005646-xhx9pzhj 1276 1 36 36 CD cord-005646-xhx9pzhj 1276 2 wks wks NN cord-005646-xhx9pzhj 1276 3 , , , cord-005646-xhx9pzhj 1276 4 TOBRA TOBRA NNP cord-005646-xhx9pzhj 1276 5 concentrations concentration NNS cord-005646-xhx9pzhj 1276 6 were be VBD cord-005646-xhx9pzhj 1276 7 analyzed analyze VBN cord-005646-xhx9pzhj 1276 8 by by IN cord-005646-xhx9pzhj 1276 9 TDX TDX NNP cord-005646-xhx9pzhj 1276 10 - - HYPH cord-005646-xhx9pzhj 1276 11 assay assay NN cord-005646-xhx9pzhj 1276 12 , , , cord-005646-xhx9pzhj 1276 13 A a DT cord-005646-xhx9pzhj 1276 14 one one CD cord-005646-xhx9pzhj 1276 15 - - HYPH cord-005646-xhx9pzhj 1276 16 compartment compartment NN cord-005646-xhx9pzhj 1276 17 model model NN cord-005646-xhx9pzhj 1276 18 was be VBD cord-005646-xhx9pzhj 1276 19 assumed assume VBN cord-005646-xhx9pzhj 1276 20 and and CC cord-005646-xhx9pzhj 1276 21 non non JJ cord-005646-xhx9pzhj 1276 22 - - JJ cord-005646-xhx9pzhj 1276 23 linear linear JJ cord-005646-xhx9pzhj 1276 24 mixed mixed JJ cord-005646-xhx9pzhj 1276 25 effect effect NN cord-005646-xhx9pzhj 1276 26 modelling modelling NN cord-005646-xhx9pzhj 1276 27 ( ( -LRB- cord-005646-xhx9pzhj 1276 28 using use VBG cord-005646-xhx9pzhj 1276 29 NONMEM NONMEM NNP cord-005646-xhx9pzhj 1276 30 ) ) -RRB- cord-005646-xhx9pzhj 1276 31 was be VBD cord-005646-xhx9pzhj 1276 32 applied apply VBN cord-005646-xhx9pzhj 1276 33 to to IN cord-005646-xhx9pzhj 1276 34 the the DT cord-005646-xhx9pzhj 1276 35 data datum NNS cord-005646-xhx9pzhj 1276 36 , , , cord-005646-xhx9pzhj 1276 37 A a DT cord-005646-xhx9pzhj 1276 38 trough trough NN cord-005646-xhx9pzhj 1276 39 level level NN cord-005646-xhx9pzhj 1276 40 < < XX cord-005646-xhx9pzhj 1276 41 2 2 CD cord-005646-xhx9pzhj 1276 42 mg mg NNP cord-005646-xhx9pzhj 1276 43 / / SYM cord-005646-xhx9pzhj 1276 44 L L NNP cord-005646-xhx9pzhj 1276 45 and and CC cord-005646-xhx9pzhj 1276 46 a a DT cord-005646-xhx9pzhj 1276 47 peak peak NN cord-005646-xhx9pzhj 1276 48 level level NN cord-005646-xhx9pzhj 1276 49 between between IN cord-005646-xhx9pzhj 1276 50 6 6 CD cord-005646-xhx9pzhj 1276 51 and and CC cord-005646-xhx9pzhj 1276 52 10 10 CD cord-005646-xhx9pzhj 1277 1 mg mg NNP cord-005646-xhx9pzhj 1277 2 / / SYM cord-005646-xhx9pzhj 1277 3 L L NNP cord-005646-xhx9pzhj 1277 4 was be VBD cord-005646-xhx9pzhj 1277 5 required require VBN cord-005646-xhx9pzhj 1277 6 , , , cord-005646-xhx9pzhj 1278 1 With with IN cord-005646-xhx9pzhj 1278 2 the the DT cord-005646-xhx9pzhj 1278 3 present present JJ cord-005646-xhx9pzhj 1278 4 dosage dosage NN cord-005646-xhx9pzhj 1278 5 scheme scheme NN cord-005646-xhx9pzhj 1278 6 40 40 CD cord-005646-xhx9pzhj 1278 7 % % NN cord-005646-xhx9pzhj 1278 8 of of IN cord-005646-xhx9pzhj 1278 9 the the DT cord-005646-xhx9pzhj 1278 10 trough trough NN cord-005646-xhx9pzhj 1278 11 levels level NNS cord-005646-xhx9pzhj 1278 12 were be VBD cord-005646-xhx9pzhj 1278 13 too too RB cord-005646-xhx9pzhj 1278 14 high high JJ cord-005646-xhx9pzhj 1278 15 and and CC cord-005646-xhx9pzhj 1278 16 almost almost RB cord-005646-xhx9pzhj 1278 17 60 60 CD cord-005646-xhx9pzhj 1278 18 % % NN cord-005646-xhx9pzhj 1278 19 of of IN cord-005646-xhx9pzhj 1278 20 the the DT cord-005646-xhx9pzhj 1278 21 peak peak NN cord-005646-xhx9pzhj 1278 22 levels level NNS cord-005646-xhx9pzhj 1278 23 too too RB cord-005646-xhx9pzhj 1278 24 low low JJ cord-005646-xhx9pzhj 1278 25 . . . cord-005646-xhx9pzhj 1279 1 Calculations calculation NNS cord-005646-xhx9pzhj 1279 2 showed show VBD cord-005646-xhx9pzhj 1279 3 that that IN cord-005646-xhx9pzhj 1279 4 the the DT cord-005646-xhx9pzhj 1279 5 following follow VBG cord-005646-xhx9pzhj 1279 6 dosage dosage NN cord-005646-xhx9pzhj 1279 7 schedule schedule NN cord-005646-xhx9pzhj 1279 8 should should MD cord-005646-xhx9pzhj 1279 9 result result VB cord-005646-xhx9pzhj 1279 10 in in IN cord-005646-xhx9pzhj 1279 11 optimal optimal JJ cord-005646-xhx9pzhj 1279 12 levels level NNS cord-005646-xhx9pzhj 1279 13 of of IN cord-005646-xhx9pzhj 1279 14 TOBRA TOBRA NNP cord-005646-xhx9pzhj 1279 15 . . . cord-005646-xhx9pzhj 1280 1 preterm preterm JJ cord-005646-xhx9pzhj 1280 2 infants infant NNS cord-005646-xhx9pzhj 1280 3 GAs ga VBZ cord-005646-xhx9pzhj 1280 4 < < XX cord-005646-xhx9pzhj 1280 5 28 28 CD cord-005646-xhx9pzhj 1280 6 wks wk NNS cord-005646-xhx9pzhj 1280 7 : : : cord-005646-xhx9pzhj 1280 8 6 6 CD cord-005646-xhx9pzhj 1280 9 mg mg NN cord-005646-xhx9pzhj 1281 1 q48h q48h NNS cord-005646-xhx9pzhj 1281 2 preterm preterm JJR cord-005646-xhx9pzhj 1281 3 infants infant NNS cord-005646-xhx9pzhj 1281 4 GAs ga VBZ cord-005646-xhx9pzhj 1281 5 28 28 CD cord-005646-xhx9pzhj 1281 6 - - SYM cord-005646-xhx9pzhj 1281 7 36 36 CD cord-005646-xhx9pzhj 1281 8 wks wks NN cord-005646-xhx9pzhj 1281 9 : : : cord-005646-xhx9pzhj 1281 10 4.5 4.5 CD cord-005646-xhx9pzhj 1281 11 mg mg NN cord-005646-xhx9pzhj 1282 1 q36h q36h VBG cord-005646-xhx9pzhj 1282 2 preterm preterm JJ cord-005646-xhx9pzhj 1282 3 infants infant NNS cord-005646-xhx9pzhj 1282 4 GAs ga VBZ cord-005646-xhx9pzhj 1282 5 > > SYM cord-005646-xhx9pzhj 1282 6 36 36 CD cord-005646-xhx9pzhj 1282 7 wks wks NN cord-005646-xhx9pzhj 1282 8 : : : cord-005646-xhx9pzhj 1283 1 The the DT cord-005646-xhx9pzhj 1283 2 currently currently RB cord-005646-xhx9pzhj 1283 3 recommended recommend VBN cord-005646-xhx9pzhj 1283 4 dosage dosage NN cord-005646-xhx9pzhj 1283 5 schedules schedule NNS cord-005646-xhx9pzhj 1283 6 for for IN cord-005646-xhx9pzhj 1283 7 TOEiRA toeira JJ cord-005646-xhx9pzhj 1283 8 result result NN cord-005646-xhx9pzhj 1283 9 in in IN cord-005646-xhx9pzhj 1283 10 high high JJ cord-005646-xhx9pzhj 1283 11 trough trough NN cord-005646-xhx9pzhj 1283 12 and and CC cord-005646-xhx9pzhj 1283 13 low low JJ cord-005646-xhx9pzhj 1283 14 peak peak NN cord-005646-xhx9pzhj 1283 15 levels level NNS cord-005646-xhx9pzhj 1283 16 . . . cord-005646-xhx9pzhj 1284 1 Prolongation prolongation NN cord-005646-xhx9pzhj 1284 2 of of IN cord-005646-xhx9pzhj 1284 3 the the DT cord-005646-xhx9pzhj 1284 4 dosing dosing NN cord-005646-xhx9pzhj 1284 5 interval interval NN cord-005646-xhx9pzhj 1284 6 and and CC cord-005646-xhx9pzhj 1284 7 increasing increase VBG cord-005646-xhx9pzhj 1284 8 the the DT cord-005646-xhx9pzhj 1284 9 amount amount NN cord-005646-xhx9pzhj 1284 10 of of IN cord-005646-xhx9pzhj 1284 11 drug drug NN cord-005646-xhx9pzhj 1284 12 per per IN cord-005646-xhx9pzhj 1284 13 dose dose NN cord-005646-xhx9pzhj 1284 14 according accord VBG cord-005646-xhx9pzhj 1284 15 to to IN cord-005646-xhx9pzhj 1284 16 the the DT cord-005646-xhx9pzhj 1284 17 above above JJ cord-005646-xhx9pzhj 1284 18 scheme scheme NN cord-005646-xhx9pzhj 1284 19 will will MD cord-005646-xhx9pzhj 1284 20 improve improve VB cord-005646-xhx9pzhj 1284 21 TOBRA TOBRA NNP cord-005646-xhx9pzhj 1284 22 level level NN cord-005646-xhx9pzhj 1284 23 control control NN cord-005646-xhx9pzhj 1284 24 . . . cord-005646-xhx9pzhj 1285 1 Since since IN cord-005646-xhx9pzhj 1285 2 January January NNP cord-005646-xhx9pzhj 1285 3 1993 1993 CD cord-005646-xhx9pzhj 1285 4 British british JJ cord-005646-xhx9pzhj 1285 5 clinicians clinician NNS cord-005646-xhx9pzhj 1285 6 have have VBP cord-005646-xhx9pzhj 1285 7 been be VBN cord-005646-xhx9pzhj 1285 8 conducting conduct VBG cord-005646-xhx9pzhj 1285 9 a a DT cord-005646-xhx9pzhj 1285 10 randomized randomized JJ cord-005646-xhx9pzhj 1285 11 controlled control VBN cord-005646-xhx9pzhj 1285 12 trial trial NN cord-005646-xhx9pzhj 1285 13 of of IN cord-005646-xhx9pzhj 1285 14 neonatal neonatal JJ cord-005646-xhx9pzhj 1285 15 ECMO ECMO NNP cord-005646-xhx9pzhj 1285 16 . . . cord-005646-xhx9pzhj 1286 1 Mature mature JJ cord-005646-xhx9pzhj 1286 2 infants infant NNS cord-005646-xhx9pzhj 1286 3 ( ( -LRB- cord-005646-xhx9pzhj 1286 4 > > XX cord-005646-xhx9pzhj 1286 5 -35 -35 CD cord-005646-xhx9pzhj 1286 6 weeks week NNS cord-005646-xhx9pzhj 1286 7 gestation gestation NN cord-005646-xhx9pzhj 1286 8 and and CC cord-005646-xhx9pzhj 1286 9 birthweight birthweight JJ cord-005646-xhx9pzhj 1286 10 2 2 CD cord-005646-xhx9pzhj 1286 11 2 2 CD cord-005646-xhx9pzhj 1286 12 kg kg NNS cord-005646-xhx9pzhj 1286 13 ) ) -RRB- cord-005646-xhx9pzhj 1286 14 with with IN cord-005646-xhx9pzhj 1286 15 severe severe JJ cord-005646-xhx9pzhj 1286 16 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 1286 17 failure failure NN cord-005646-xhx9pzhj 1286 18 have have VBP cord-005646-xhx9pzhj 1286 19 been be VBN cord-005646-xhx9pzhj 1286 20 randomized randomize VBN cord-005646-xhx9pzhj 1286 21 to to TO cord-005646-xhx9pzhj 1286 22 receive receive VB cord-005646-xhx9pzhj 1286 23 continued continued JJ cord-005646-xhx9pzhj 1286 24 care care NN cord-005646-xhx9pzhj 1286 25 in in IN cord-005646-xhx9pzhj 1286 26 their -PRON- PRP$ cord-005646-xhx9pzhj 1286 27 referring refer VBG cord-005646-xhx9pzhj 1286 28 institution institution NN cord-005646-xhx9pzhj 1286 29 or or CC cord-005646-xhx9pzhj 1286 30 referral referral NN cord-005646-xhx9pzhj 1286 31 to to IN cord-005646-xhx9pzhj 1286 32 a a DT cord-005646-xhx9pzhj 1286 33 designated designate VBN cord-005646-xhx9pzhj 1286 34 ECMO ECMO NNP cord-005646-xhx9pzhj 1286 35 centre centre NN cord-005646-xhx9pzhj 1286 36 for for IN cord-005646-xhx9pzhj 1286 37 further further JJ cord-005646-xhx9pzhj 1286 38 management management NN cord-005646-xhx9pzhj 1286 39 . . . cord-005646-xhx9pzhj 1287 1 We -PRON- PRP cord-005646-xhx9pzhj 1287 2 now now RB cord-005646-xhx9pzhj 1287 3 present present VBP cord-005646-xhx9pzhj 1287 4 the the DT cord-005646-xhx9pzhj 1287 5 preliminary preliminary JJ cord-005646-xhx9pzhj 1287 6 results result NNS cord-005646-xhx9pzhj 1287 7 which which WDT cord-005646-xhx9pzhj 1287 8 have have VBP cord-005646-xhx9pzhj 1287 9 prompted prompt VBN cord-005646-xhx9pzhj 1287 10 closure closure NN cord-005646-xhx9pzhj 1287 11 of of IN cord-005646-xhx9pzhj 1287 12 recruitment recruitment NN cord-005646-xhx9pzhj 1287 13 to to IN cord-005646-xhx9pzhj 1287 14 this this DT cord-005646-xhx9pzhj 1287 15 trial trial NN cord-005646-xhx9pzhj 1287 16 . . . cord-005646-xhx9pzhj 1288 1 The the DT cord-005646-xhx9pzhj 1288 2 final final JJ cord-005646-xhx9pzhj 1288 3 outcome outcome NN cord-005646-xhx9pzhj 1288 4 will will MD cord-005646-xhx9pzhj 1288 5 be be VB cord-005646-xhx9pzhj 1288 6 assessed assess VBN cord-005646-xhx9pzhj 1288 7 as as RB cord-005646-xhx9pzhj 1288 8 intact intact JJ cord-005646-xhx9pzhj 1288 9 survival survival NN cord-005646-xhx9pzhj 1288 10 against against IN cord-005646-xhx9pzhj 1288 11 death death NN cord-005646-xhx9pzhj 1288 12 or or CC cord-005646-xhx9pzhj 1288 13 severe severe JJ cord-005646-xhx9pzhj 1288 14 disability disability NN cord-005646-xhx9pzhj 1288 15 at at IN cord-005646-xhx9pzhj 1288 16 one one CD cord-005646-xhx9pzhj 1288 17 year year NN cord-005646-xhx9pzhj 1288 18 of of IN cord-005646-xhx9pzhj 1288 19 age age NN cord-005646-xhx9pzhj 1288 20 for for IN cord-005646-xhx9pzhj 1288 21 all all PDT cord-005646-xhx9pzhj 1288 22 the the DT cord-005646-xhx9pzhj 1288 23 recruited recruit VBN cord-005646-xhx9pzhj 1288 24 patients patient NNS cord-005646-xhx9pzhj 1288 25 . . . cord-005646-xhx9pzhj 1289 1 Patients patient NNS cord-005646-xhx9pzhj 1289 2 were be VBD cord-005646-xhx9pzhj 1289 3 categorised categorise VBN cord-005646-xhx9pzhj 1289 4 by by IN cord-005646-xhx9pzhj 1289 5 diagnosis diagnosis NN cord-005646-xhx9pzhj 1289 6 such such JJ cord-005646-xhx9pzhj 1289 7 as as IN cord-005646-xhx9pzhj 1289 8 isolated isolate VBN cord-005646-xhx9pzhj 1289 9 persistent persistent JJ cord-005646-xhx9pzhj 1289 10 fetal fetal JJ cord-005646-xhx9pzhj 1289 11 circulation circulation NN cord-005646-xhx9pzhj 1289 12 , , , cord-005646-xhx9pzhj 1289 13 secondary secondary JJ cord-005646-xhx9pzhj 1289 14 persistent persistent JJ cord-005646-xhx9pzhj 1289 15 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1289 16 hypertension hypertension NN cord-005646-xhx9pzhj 1289 17 of of IN cord-005646-xhx9pzhj 1289 18 the the DT cord-005646-xhx9pzhj 1289 19 newborn newborn JJ cord-005646-xhx9pzhj 1289 20 or or CC cord-005646-xhx9pzhj 1289 21 congenital congenital JJ cord-005646-xhx9pzhj 1289 22 diaphragmatic diaphragmatic JJ cord-005646-xhx9pzhj 1289 23 hernia hernia NN cord-005646-xhx9pzhj 1289 24 and and CC cord-005646-xhx9pzhj 1289 25 by by IN cord-005646-xhx9pzhj 1289 26 severity severity NN cord-005646-xhx9pzhj 1289 27 of of IN cord-005646-xhx9pzhj 1289 28 illness illness NN cord-005646-xhx9pzhj 1289 29 at at IN cord-005646-xhx9pzhj 1289 30 the the DT cord-005646-xhx9pzhj 1289 31 point point NN cord-005646-xhx9pzhj 1289 32 of of IN cord-005646-xhx9pzhj 1289 33 first first JJ cord-005646-xhx9pzhj 1289 34 contact contact NN cord-005646-xhx9pzhj 1289 35 with with IN cord-005646-xhx9pzhj 1289 36 the the DT cord-005646-xhx9pzhj 1289 37 clinical clinical JJ cord-005646-xhx9pzhj 1289 38 coordinators coordinator NNS cord-005646-xhx9pzhj 1289 39 of of IN cord-005646-xhx9pzhj 1289 40 the the DT cord-005646-xhx9pzhj 1289 41 trial trial NN cord-005646-xhx9pzhj 1289 42 -judged -judge VBD cord-005646-xhx9pzhj 1289 43 primarily primarily RB cord-005646-xhx9pzhj 1289 44 by by IN cord-005646-xhx9pzhj 1289 45 the the DT cord-005646-xhx9pzhj 1289 46 oxygenation oxygenation NN cord-005646-xhx9pzhj 1289 47 index index NN cord-005646-xhx9pzhj 1289 48 ( ( -LRB- cord-005646-xhx9pzhj 1289 49 240 240 CD cord-005646-xhx9pzhj 1289 50 before before IN cord-005646-xhx9pzhj 1289 51 randomization randomization NN cord-005646-xhx9pzhj 1289 52 ) ) -RRB- cord-005646-xhx9pzhj 1289 53 . . . cord-005646-xhx9pzhj 1290 1 180 180 CD cord-005646-xhx9pzhj 1290 2 patients patient NNS cord-005646-xhx9pzhj 1290 3 were be VBD cord-005646-xhx9pzhj 1290 4 randomized randomize VBN cord-005646-xhx9pzhj 1290 5 ( ( -LRB- cord-005646-xhx9pzhj 1290 6 90 90 CD cord-005646-xhx9pzhj 1290 7 in in IN cord-005646-xhx9pzhj 1290 8 each each DT cord-005646-xhx9pzhj 1290 9 arm arm NN cord-005646-xhx9pzhj 1290 10 ) ) -RRB- cord-005646-xhx9pzhj 1290 11 . . . cord-005646-xhx9pzhj 1291 1 Hospital hospital NN cord-005646-xhx9pzhj 1291 2 outcome outcome NN cord-005646-xhx9pzhj 1291 3 data datum NNS cord-005646-xhx9pzhj 1291 4 are be VBP cord-005646-xhx9pzhj 1291 5 reported report VBN cord-005646-xhx9pzhj 1291 6 for for IN cord-005646-xhx9pzhj 1291 7 all all DT cord-005646-xhx9pzhj 1291 8 patients patient NNS cord-005646-xhx9pzhj 1291 9 and and CC cord-005646-xhx9pzhj 1291 10 1 1 CD cord-005646-xhx9pzhj 1291 11 year year NN cord-005646-xhx9pzhj 1291 12 outcomes outcome NNS cord-005646-xhx9pzhj 1291 13 on on IN cord-005646-xhx9pzhj 1291 14 t18 t18 NNP cord-005646-xhx9pzhj 1291 15 ( ( -LRB- cord-005646-xhx9pzhj 1291 16 65 65 CD cord-005646-xhx9pzhj 1291 17 survivors survivor NNS cord-005646-xhx9pzhj 1291 18 ) ) -RRB- cord-005646-xhx9pzhj 1291 19 . . . cord-005646-xhx9pzhj 1292 1 At at IN cord-005646-xhx9pzhj 1292 2 this this DT cord-005646-xhx9pzhj 1292 3 stage stage NN cord-005646-xhx9pzhj 1292 4 26 26 CD cord-005646-xhx9pzhj 1292 5 of of IN cord-005646-xhx9pzhj 1292 6 the the DT cord-005646-xhx9pzhj 1292 7 babies baby NNS cord-005646-xhx9pzhj 1292 8 allocated allocate VBN cord-005646-xhx9pzhj 1292 9 to to IN cord-005646-xhx9pzhj 1292 10 ECMO ECMO NNP cord-005646-xhx9pzhj 1292 11 are be VBP cord-005646-xhx9pzhj 1292 12 known know VBN cord-005646-xhx9pzhj 1292 13 to to TO cord-005646-xhx9pzhj 1292 14 have have VB cord-005646-xhx9pzhj 1292 15 died die VBN cord-005646-xhx9pzhj 1292 16 compared compare VBN cord-005646-xhx9pzhj 1292 17 to to IN cord-005646-xhx9pzhj 1292 18 52 52 CD cord-005646-xhx9pzhj 1292 19 of of IN cord-005646-xhx9pzhj 1292 20 those those DT cord-005646-xhx9pzhj 1292 21 allocated allocate VBN cord-005646-xhx9pzhj 1292 22 to to IN cord-005646-xhx9pzhj 1292 23 conventional conventional JJ cord-005646-xhx9pzhj 1292 24 management management NN cord-005646-xhx9pzhj 1292 25 ( ( -LRB- cord-005646-xhx9pzhj 1292 26 RR RR NNP cord-005646-xhx9pzhj 1292 27 0.5 0.5 CD cord-005646-xhx9pzhj 1292 28 ; ; : cord-005646-xhx9pzhj 1292 29 95 95 CD cord-005646-xhx9pzhj 1292 30 % % NN cord-005646-xhx9pzhj 1292 31 CI CI NNP cord-005646-xhx9pzhj 1292 32 0.35 0.35 CD cord-005646-xhx9pzhj 1292 33 - - HYPH cord-005646-xhx9pzhj 1292 34 0.72 0.72 CD cord-005646-xhx9pzhj 1292 35 ; ; : cord-005646-xhx9pzhj 1292 36 P=0.0002 P=0.0002 NNP cord-005646-xhx9pzhj 1292 37 ) ) -RRB- cord-005646-xhx9pzhj 1292 38 . . . cord-005646-xhx9pzhj 1293 1 Fewer few JJR cord-005646-xhx9pzhj 1293 2 deaths death NNS cord-005646-xhx9pzhj 1293 3 have have VBP cord-005646-xhx9pzhj 1293 4 been be VBN cord-005646-xhx9pzhj 1293 5 obsea obsea NN cord-005646-xhx9pzhj 1293 6 - - HYPH cord-005646-xhx9pzhj 1293 7 ved ved NNP cord-005646-xhx9pzhj 1294 1 amongst amongst IN cord-005646-xhx9pzhj 1294 2 ECMO ECMO NNP cord-005646-xhx9pzhj 1294 3 allocated allocate VBD cord-005646-xhx9pzhj 1294 4 babies baby NNS cord-005646-xhx9pzhj 1294 5 in in IN cord-005646-xhx9pzhj 1294 6 all all PDT cord-005646-xhx9pzhj 1294 7 the the DT cord-005646-xhx9pzhj 1294 8 diagnostic diagnostic JJ cord-005646-xhx9pzhj 1294 9 categories category NNS cord-005646-xhx9pzhj 1294 10 used use VBN cord-005646-xhx9pzhj 1294 11 . . . cord-005646-xhx9pzhj 1295 1 A a DT cord-005646-xhx9pzhj 1295 2 28 28 CD cord-005646-xhx9pzhj 1295 3 % % NN cord-005646-xhx9pzhj 1295 4 incidence incidence NN cord-005646-xhx9pzhj 1295 5 of of IN cord-005646-xhx9pzhj 1295 6 disability disability NN cord-005646-xhx9pzhj 1295 7 and and CC cord-005646-xhx9pzhj 1295 8 impah impah NNP cord-005646-xhx9pzhj 1296 1 ~nent ~nent NNP cord-005646-xhx9pzhj 1296 2 has have VBZ cord-005646-xhx9pzhj 1296 3 been be VBN cord-005646-xhx9pzhj 1296 4 observed observe VBN cord-005646-xhx9pzhj 1296 5 amongst amongst IN cord-005646-xhx9pzhj 1296 6 survivors survivor NNS cord-005646-xhx9pzhj 1296 7 . . . cord-005646-xhx9pzhj 1297 1 This this DT cord-005646-xhx9pzhj 1297 2 rate rate NN cord-005646-xhx9pzhj 1297 3 is be VBZ cord-005646-xhx9pzhj 1297 4 similar similar JJ cord-005646-xhx9pzhj 1297 5 in in IN cord-005646-xhx9pzhj 1297 6 both both DT cord-005646-xhx9pzhj 1297 7 groups group NNS cord-005646-xhx9pzhj 1297 8 and and CC cord-005646-xhx9pzhj 1297 9 the the DT cord-005646-xhx9pzhj 1297 10 survival survival NN cord-005646-xhx9pzhj 1297 11 advantage advantage NN cord-005646-xhx9pzhj 1297 12 is be VBZ cord-005646-xhx9pzhj 1297 13 not not RB cord-005646-xhx9pzhj 1297 14 offset offset VBN cord-005646-xhx9pzhj 1297 15 by by IN cord-005646-xhx9pzhj 1297 16 an an DT cord-005646-xhx9pzhj 1297 17 increased increase VBN cord-005646-xhx9pzhj 1297 18 rate rate NN cord-005646-xhx9pzhj 1297 19 of of IN cord-005646-xhx9pzhj 1297 20 disability disability NN cord-005646-xhx9pzhj 1297 21 or or CC cord-005646-xhx9pzhj 1297 22 impairment impairment NN cord-005646-xhx9pzhj 1297 23 following follow VBG cord-005646-xhx9pzhj 1297 24 allocation allocation NN cord-005646-xhx9pzhj 1297 25 to to IN cord-005646-xhx9pzhj 1297 26 ECMO ECMO NNP cord-005646-xhx9pzhj 1297 27 . . . cord-005646-xhx9pzhj 1298 1 We -PRON- PRP cord-005646-xhx9pzhj 1298 2 consider consider VBP cord-005646-xhx9pzhj 1298 3 that that IN cord-005646-xhx9pzhj 1298 4 these these DT cord-005646-xhx9pzhj 1298 5 data datum NNS cord-005646-xhx9pzhj 1298 6 combined combine VBN cord-005646-xhx9pzhj 1298 7 with with IN cord-005646-xhx9pzhj 1298 8 those those DT cord-005646-xhx9pzhj 1298 9 available available JJ cord-005646-xhx9pzhj 1298 10 from from IN cord-005646-xhx9pzhj 1298 11 other other JJ cord-005646-xhx9pzhj 1298 12 studies study NNS cord-005646-xhx9pzhj 1298 13 provide provide VBP cord-005646-xhx9pzhj 1298 14 conclusive conclusive JJ cord-005646-xhx9pzhj 1298 15 evidence evidence NN cord-005646-xhx9pzhj 1298 16 that that IN cord-005646-xhx9pzhj 1298 17 the the DT cord-005646-xhx9pzhj 1298 18 survival survival NN cord-005646-xhx9pzhj 1298 19 to to TO cord-005646-xhx9pzhj 1298 20 discharge discharge VB cord-005646-xhx9pzhj 1298 21 from from IN cord-005646-xhx9pzhj 1298 22 hospital hospital NN cord-005646-xhx9pzhj 1298 23 is be VBZ cord-005646-xhx9pzhj 1298 24 substantially substantially RB cord-005646-xhx9pzhj 1298 25 higher high JJR cord-005646-xhx9pzhj 1298 26 in in IN cord-005646-xhx9pzhj 1298 27 patients patient NNS cord-005646-xhx9pzhj 1298 28 allocated allocate VBN cord-005646-xhx9pzhj 1298 29 to to IN cord-005646-xhx9pzhj 1298 30 ECMO ECMO NNP cord-005646-xhx9pzhj 1298 31 than than IN cord-005646-xhx9pzhj 1298 32 in in IN cord-005646-xhx9pzhj 1298 33 comparable comparable JJ cord-005646-xhx9pzhj 1298 34 infants infant NNS cord-005646-xhx9pzhj 1298 35 not not RB cord-005646-xhx9pzhj 1298 36 so so RB cord-005646-xhx9pzhj 1298 37 allocated allocate VBN cord-005646-xhx9pzhj 1298 38 . . . cord-005646-xhx9pzhj 1299 1 Therefore therefore RB cord-005646-xhx9pzhj 1299 2 recruitment recruitment VB cord-005646-xhx9pzhj 1299 3 to to IN cord-005646-xhx9pzhj 1299 4 this this DT cord-005646-xhx9pzhj 1299 5 trial trial NN cord-005646-xhx9pzhj 1299 6 has have VBZ cord-005646-xhx9pzhj 1299 7 been be VBN cord-005646-xhx9pzhj 1299 8 closed close VBN cord-005646-xhx9pzhj 1299 9 whist whist NN cord-005646-xhx9pzhj 1299 10 awaiting await VBG cord-005646-xhx9pzhj 1299 11 complete complete JJ cord-005646-xhx9pzhj 1299 12 one one CD cord-005646-xhx9pzhj 1299 13 year year NN cord-005646-xhx9pzhj 1299 14 outcome outcome NN cord-005646-xhx9pzhj 1299 15 data datum NNS cord-005646-xhx9pzhj 1299 16 . . . cord-005646-xhx9pzhj 1300 1 Sigston Sigston NNP cord-005646-xhx9pzhj 1300 2 PE PE NNP cord-005646-xhx9pzhj 1300 3 , , , cord-005646-xhx9pzhj 1300 4 Goldman Goldman NNP cord-005646-xhx9pzhj 1300 5 AP AP NNP cord-005646-xhx9pzhj 1300 6 . . . cord-005646-xhx9pzhj 1301 1 # # $ cord-005646-xhx9pzhj 1302 1 Keating Keating NNP cord-005646-xhx9pzhj 1302 2 J. J. NNP cord-005646-xhx9pzhj 1302 3 Crook Crook NNP cord-005646-xhx9pzhj 1302 4 R. R. NNP cord-005646-xhx9pzhj 1303 1 ~e ~e NNP cord-005646-xhx9pzhj 1304 1 DJ~. DJ~. NNP cord-005646-xhx9pzhj 1304 2 Great Great NNP cord-005646-xhx9pzhj 1304 3 Ormond Ormond NNP cord-005646-xhx9pzhj 1304 4 Street Street NNP cord-005646-xhx9pzhj 1304 5 Hospital Hospital NNP cord-005646-xhx9pzhj 1304 6 for for IN cord-005646-xhx9pzhj 1304 7 Children Children NNP cord-005646-xhx9pzhj 1304 8 NHS NHS NNP cord-005646-xhx9pzhj 1304 9 Trust Trust NNP cord-005646-xhx9pzhj 1304 10 , , , cord-005646-xhx9pzhj 1304 11 and and CC cord-005646-xhx9pzhj 1304 12 ~Biochemistry ~biochemistry ADD cord-005646-xhx9pzhj 1305 1 Department Department NNP cord-005646-xhx9pzhj 1305 2 , , , cord-005646-xhx9pzhj 1305 3 Kings Kings NNP cord-005646-xhx9pzhj 1305 4 College College NNP cord-005646-xhx9pzhj 1305 5 Hospital Hospital NNP cord-005646-xhx9pzhj 1305 6 , , , cord-005646-xhx9pzhj 1305 7 London London NNP cord-005646-xhx9pzhj 1305 8 , , , cord-005646-xhx9pzhj 1305 9 United United NNP cord-005646-xhx9pzhj 1305 10 Kingdom Kingdom NNP cord-005646-xhx9pzhj 1305 11 . . . cord-005646-xhx9pzhj 1306 1 Isoflurane Isoflurane NNP cord-005646-xhx9pzhj 1306 2 is be VBZ cord-005646-xhx9pzhj 1306 3 a a DT cord-005646-xhx9pzhj 1306 4 safe safe JJ cord-005646-xhx9pzhj 1306 5 and and CC cord-005646-xhx9pzhj 1306 6 effective effective JJ cord-005646-xhx9pzhj 1306 7 means mean NNS cord-005646-xhx9pzhj 1306 8 of of IN cord-005646-xhx9pzhj 1306 9 long long JJ cord-005646-xhx9pzhj 1306 10 term term NN cord-005646-xhx9pzhj 1306 11 sedation sedation NN cord-005646-xhx9pzhj 1306 12 in in IN cord-005646-xhx9pzhj 1306 13 both both DT cord-005646-xhx9pzhj 1306 14 children child NNS cord-005646-xhx9pzhj 1306 15 and and CC cord-005646-xhx9pzhj 1306 16 adults adult NNS cord-005646-xhx9pzhj 1306 17 in in IN cord-005646-xhx9pzhj 1306 18 the the DT cord-005646-xhx9pzhj 1306 19 intensive intensive JJ cord-005646-xhx9pzhj 1306 20 care care NN cord-005646-xhx9pzhj 1306 21 setting setting NN cord-005646-xhx9pzhj 1306 22 . . . cord-005646-xhx9pzhj 1307 1 The the DT cord-005646-xhx9pzhj 1307 2 use use NN cord-005646-xhx9pzhj 1307 3 of of IN cord-005646-xhx9pzhj 1307 4 isoflurane isoflurane NN cord-005646-xhx9pzhj 1307 5 , , , cord-005646-xhx9pzhj 1307 6 by by IN cord-005646-xhx9pzhj 1307 7 adding add VBG cord-005646-xhx9pzhj 1307 8 it -PRON- PRP cord-005646-xhx9pzhj 1307 9 to to IN cord-005646-xhx9pzhj 1307 10 the the DT cord-005646-xhx9pzhj 1307 11 sweep sweep NN cord-005646-xhx9pzhj 1307 12 gas gas NN cord-005646-xhx9pzhj 1307 13 allows allow VBZ cord-005646-xhx9pzhj 1307 14 the the DT cord-005646-xhx9pzhj 1307 15 use use NN cord-005646-xhx9pzhj 1307 16 of of IN cord-005646-xhx9pzhj 1307 17 this this DT cord-005646-xhx9pzhj 1307 18 volatile volatile JJ cord-005646-xhx9pzhj 1307 19 anaesthetic anaesthetic JJ cord-005646-xhx9pzhj 1307 20 agent agent NN cord-005646-xhx9pzhj 1307 21 in in IN cord-005646-xhx9pzhj 1307 22 patients patient NNS cord-005646-xhx9pzhj 1307 23 on on IN cord-005646-xhx9pzhj 1307 24 ECMO ECMO NNP cord-005646-xhx9pzhj 1307 25 , , , cord-005646-xhx9pzhj 1307 26 enabling enable VBG cord-005646-xhx9pzhj 1307 27 rapid rapid JJ cord-005646-xhx9pzhj 1307 28 control control NN cord-005646-xhx9pzhj 1307 29 and and CC cord-005646-xhx9pzhj 1307 30 weaning weaning NN cord-005646-xhx9pzhj 1307 31 of of IN cord-005646-xhx9pzhj 1307 32 sedation sedation NN cord-005646-xhx9pzhj 1307 33 . . . cord-005646-xhx9pzhj 1308 1 A a DT cord-005646-xhx9pzhj 1308 2 potential potential JJ cord-005646-xhx9pzhj 1308 3 problem problem NN cord-005646-xhx9pzhj 1308 4 with with IN cord-005646-xhx9pzhj 1308 5 the the DT cord-005646-xhx9pzhj 1308 6 long long JJ cord-005646-xhx9pzhj 1308 7 term term NN cord-005646-xhx9pzhj 1308 8 use use NN cord-005646-xhx9pzhj 1308 9 of of IN cord-005646-xhx9pzhj 1308 10 isoflurane isoflurane NN cord-005646-xhx9pzhj 1308 11 is be VBZ cord-005646-xhx9pzhj 1308 12 fluoride fluoride NN cord-005646-xhx9pzhj 1308 13 ion ion NN cord-005646-xhx9pzhj 1308 14 accumulation accumulation NN cord-005646-xhx9pzhj 1308 15 with with IN cord-005646-xhx9pzhj 1308 16 the the DT cord-005646-xhx9pzhj 1308 17 possibility possibility NN cord-005646-xhx9pzhj 1308 18 of of IN cord-005646-xhx9pzhj 1308 19 renal renal JJ cord-005646-xhx9pzhj 1308 20 toxicity toxicity NN cord-005646-xhx9pzhj 1308 21 , , , cord-005646-xhx9pzhj 1308 22 The the DT cord-005646-xhx9pzhj 1308 23 purpose purpose NN cord-005646-xhx9pzhj 1308 24 of of IN cord-005646-xhx9pzhj 1308 25 this this DT cord-005646-xhx9pzhj 1308 26 study study NN cord-005646-xhx9pzhj 1308 27 was be VBD cord-005646-xhx9pzhj 1308 28 to to TO cord-005646-xhx9pzhj 1308 29 assess assess VB cord-005646-xhx9pzhj 1308 30 plasma plasma NN cord-005646-xhx9pzhj 1308 31 fluoride fluoride NN cord-005646-xhx9pzhj 1308 32 levels level NNS cord-005646-xhx9pzhj 1308 33 in in IN cord-005646-xhx9pzhj 1308 34 patients patient NNS cord-005646-xhx9pzhj 1308 35 receiving receive VBG cord-005646-xhx9pzhj 1308 36 prolonged prolong VBN cord-005646-xhx9pzhj 1308 37 isoflurane isoflurane NN cord-005646-xhx9pzhj 1308 38 on on IN cord-005646-xhx9pzhj 1308 39 ECMO ECMO NNP cord-005646-xhx9pzhj 1308 40 . . . cord-005646-xhx9pzhj 1309 1 Method method NN cord-005646-xhx9pzhj 1309 2 : : : cord-005646-xhx9pzhj 1310 1 Fifteen fifteen CD cord-005646-xhx9pzhj 1310 2 infants infant NNS cord-005646-xhx9pzhj 1310 3 and and CC cord-005646-xhx9pzhj 1310 4 children child NNS cord-005646-xhx9pzhj 1310 5 ( ( -LRB- cord-005646-xhx9pzhj 1310 6 aged aged JJ cord-005646-xhx9pzhj 1310 7 1 1 CD cord-005646-xhx9pzhj 1310 8 day day NN cord-005646-xhx9pzhj 1310 9 -10 -10 NN cord-005646-xhx9pzhj 1310 10 years year NNS cord-005646-xhx9pzhj 1310 11 , , , cord-005646-xhx9pzhj 1310 12 median median JJ cord-005646-xhx9pzhj 1310 13 2 2 CD cord-005646-xhx9pzhj 1310 14 weeks week NNS cord-005646-xhx9pzhj 1310 15 ) ) -RRB- cord-005646-xhx9pzhj 1310 16 receiving receive VBG cord-005646-xhx9pzhj 1310 17 ECMO ecmo NN cord-005646-xhx9pzhj 1310 18 support support NN cord-005646-xhx9pzhj 1310 19 for for IN cord-005646-xhx9pzhj 1310 20 either either CC cord-005646-xhx9pzhj 1310 21 cardiac cardiac JJ cord-005646-xhx9pzhj 1310 22 or or CC cord-005646-xhx9pzhj 1310 23 respiratory respiratory JJ cord-005646-xhx9pzhj 1310 24 failure failure NN cord-005646-xhx9pzhj 1310 25 were be VBD cord-005646-xhx9pzhj 1310 26 recruited recruit VBN cord-005646-xhx9pzhj 1310 27 to to IN cord-005646-xhx9pzhj 1310 28 this this DT cord-005646-xhx9pzhj 1310 29 study study NN cord-005646-xhx9pzhj 1310 30 . . . cord-005646-xhx9pzhj 1311 1 The the DT cord-005646-xhx9pzhj 1311 2 patients patient NNS cord-005646-xhx9pzhj 1311 3 were be VBD cord-005646-xhx9pzhj 1311 4 sedated sedate VBN cord-005646-xhx9pzhj 1311 5 with with IN cord-005646-xhx9pzhj 1311 6 isoflurane isoflurane NNP cord-005646-xhx9pzhj 1311 7 as as RB cord-005646-xhx9pzhj 1311 8 well well RB cord-005646-xhx9pzhj 1311 9 as as IN cord-005646-xhx9pzhj 1311 10 intravenous intravenous JJ cord-005646-xhx9pzhj 1311 11 agents agent NNS cord-005646-xhx9pzhj 1311 12 ( ( -LRB- cord-005646-xhx9pzhj 1311 13 morphine morphine NN cord-005646-xhx9pzhj 1311 14 and and CC cord-005646-xhx9pzhj 1311 15 midazolam midazolam NN cord-005646-xhx9pzhj 1311 16 ) ) -RRB- cord-005646-xhx9pzhj 1311 17 . . . cord-005646-xhx9pzhj 1312 1 Isoflurane Isoflurane NNP cord-005646-xhx9pzhj 1312 2 was be VBD cord-005646-xhx9pzhj 1312 3 administered administer VBN cord-005646-xhx9pzhj 1312 4 ( ( -LRB- cord-005646-xhx9pzhj 1312 5 0 0 CD cord-005646-xhx9pzhj 1312 6 % % NN cord-005646-xhx9pzhj 1312 7 -3 -3 CD cord-005646-xhx9pzhj 1312 8 % % NN cord-005646-xhx9pzhj 1312 9 ) ) -RRB- cord-005646-xhx9pzhj 1312 10 via via IN cord-005646-xhx9pzhj 1312 11 a a DT cord-005646-xhx9pzhj 1312 12 calibrated calibrate VBN cord-005646-xhx9pzhj 1312 13 vaporiser vaporiser NN cord-005646-xhx9pzhj 1312 14 to to IN cord-005646-xhx9pzhj 1312 15 the the DT cord-005646-xhx9pzhj 1312 16 sweep sweep NN cord-005646-xhx9pzhj 1312 17 gas gas NN cord-005646-xhx9pzhj 1312 18 , , , cord-005646-xhx9pzhj 1312 19 adjusting adjust VBG cord-005646-xhx9pzhj 1312 20 the the DT cord-005646-xhx9pzhj 1312 21 level level NN cord-005646-xhx9pzhj 1312 22 to to TO cord-005646-xhx9pzhj 1312 23 maintain maintain VB cord-005646-xhx9pzhj 1312 24 adequate adequate JJ cord-005646-xhx9pzhj 1312 25 sedation sedation NN cord-005646-xhx9pzhj 1312 26 . . . cord-005646-xhx9pzhj 1313 1 Blood blood NN cord-005646-xhx9pzhj 1313 2 samples sample NNS cord-005646-xhx9pzhj 1313 3 were be VBD cord-005646-xhx9pzhj 1313 4 obtained obtain VBN cord-005646-xhx9pzhj 1313 5 on on IN cord-005646-xhx9pzhj 1313 6 a a DT cord-005646-xhx9pzhj 1313 7 daily daily JJ cord-005646-xhx9pzhj 1313 8 basis basis NN cord-005646-xhx9pzhj 1313 9 for for IN cord-005646-xhx9pzhj 1313 10 plasma plasma NN cord-005646-xhx9pzhj 1313 11 inorganic inorganic JJ cord-005646-xhx9pzhj 1313 12 fluoride fluoride NN cord-005646-xhx9pzhj 1313 13 assay assay NN cord-005646-xhx9pzhj 1313 14 . . . cord-005646-xhx9pzhj 1314 1 The the DT cord-005646-xhx9pzhj 1314 2 relationship relationship NN cord-005646-xhx9pzhj 1314 3 between between IN cord-005646-xhx9pzhj 1314 4 plasma plasma NN cord-005646-xhx9pzhj 1314 5 fluoride fluoride NN cord-005646-xhx9pzhj 1314 6 and and CC cord-005646-xhx9pzhj 1314 7 amount amount NN cord-005646-xhx9pzhj 1314 8 of of IN cord-005646-xhx9pzhj 1314 9 isoflurane isoflurane NN cord-005646-xhx9pzhj 1314 10 administered administer VBN cord-005646-xhx9pzhj 1314 11 , , , cord-005646-xhx9pzhj 1314 12 as as IN cord-005646-xhx9pzhj 1314 13 % % NN cord-005646-xhx9pzhj 1314 14 -hours -hours CD cord-005646-xhx9pzhj 1315 1 ( ( -LRB- cord-005646-xhx9pzhj 1315 2 vaporiser vaporiser NN cord-005646-xhx9pzhj 1315 3 setting set VBG cord-005646-xhx9pzhj 1315 4 in in IN cord-005646-xhx9pzhj 1315 5 % % NN cord-005646-xhx9pzhj 1315 6 x x SYM cord-005646-xhx9pzhj 1315 7 hours hour NNS cord-005646-xhx9pzhj 1315 8 ) ) -RRB- cord-005646-xhx9pzhj 1315 9 was be VBD cord-005646-xhx9pzhj 1315 10 calculated calculate VBN cord-005646-xhx9pzhj 1315 11 by by IN cord-005646-xhx9pzhj 1315 12 linear linear JJ cord-005646-xhx9pzhj 1315 13 regression regression NN cord-005646-xhx9pzhj 1315 14 . . . cord-005646-xhx9pzhj 1316 1 Results result NNS cord-005646-xhx9pzhj 1316 2 : : : cord-005646-xhx9pzhj 1317 1 The the DT cord-005646-xhx9pzhj 1317 2 duration duration NN cord-005646-xhx9pzhj 1317 3 of of IN cord-005646-xhx9pzhj 1317 4 ECMO ecmo NN cord-005646-xhx9pzhj 1317 5 ranged range VBD cord-005646-xhx9pzhj 1317 6 from from IN cord-005646-xhx9pzhj 1317 7 42 42 CD cord-005646-xhx9pzhj 1317 8 to to IN cord-005646-xhx9pzhj 1317 9 532 532 CD cord-005646-xhx9pzhj 1317 10 ( ( -LRB- cord-005646-xhx9pzhj 1317 11 mean mean VB cord-005646-xhx9pzhj 1317 12 207 207 CD cord-005646-xhx9pzhj 1317 13 ) ) -RRB- cord-005646-xhx9pzhj 1317 14 hours hour NNS cord-005646-xhx9pzhj 1317 15 , , , cord-005646-xhx9pzhj 1317 16 during during IN cord-005646-xhx9pzhj 1317 17 which which WDT cord-005646-xhx9pzhj 1317 18 the the DT cord-005646-xhx9pzhj 1317 19 amount amount NN cord-005646-xhx9pzhj 1317 20 of of IN cord-005646-xhx9pzhj 1317 21 isoflurane isoflurane NN cord-005646-xhx9pzhj 1317 22 administered administer VBN cord-005646-xhx9pzhj 1317 23 varied varied JJ cord-005646-xhx9pzhj 1317 24 from from IN cord-005646-xhx9pzhj 1317 25 7 7 CD cord-005646-xhx9pzhj 1317 26 to to IN cord-005646-xhx9pzhj 1317 27 418 418 CD cord-005646-xhx9pzhj 1317 28 ( ( -LRB- cord-005646-xhx9pzhj 1317 29 mean mean VB cord-005646-xhx9pzhj 1317 30 168 168 CD cord-005646-xhx9pzhj 1317 31 ) ) -RRB- cord-005646-xhx9pzhj 1317 32 % % NN cord-005646-xhx9pzhj 1318 1 -hours -hours : cord-005646-xhx9pzhj 1318 2 . . . cord-005646-xhx9pzhj 1319 1 75 75 CD cord-005646-xhx9pzhj 1319 2 blood blood NN cord-005646-xhx9pzhj 1319 3 samples sample NNS cord-005646-xhx9pzhj 1319 4 were be VBD cord-005646-xhx9pzhj 1319 5 anaiysed anaiyse VBN cord-005646-xhx9pzhj 1319 6 , , , cord-005646-xhx9pzhj 1319 7 demonstrating demonstrate VBG cord-005646-xhx9pzhj 1319 8 individual individual JJ cord-005646-xhx9pzhj 1319 9 peak peak NN cord-005646-xhx9pzhj 1319 10 plasma plasma NN cord-005646-xhx9pzhj 1319 11 fluoride fluoride NN cord-005646-xhx9pzhj 1319 12 levels level NNS cord-005646-xhx9pzhj 1319 13 of of IN cord-005646-xhx9pzhj 1319 14 2.7 2.7 CD cord-005646-xhx9pzhj 1319 15 to to IN cord-005646-xhx9pzhj 1319 16 16.5#mol/1 16.5#mol/1 CD cord-005646-xhx9pzhj 1319 17 , , , cord-005646-xhx9pzhj 1319 18 mean mean VB cord-005646-xhx9pzhj 1320 1 7,1p.mollI 7,1p.molli CD cord-005646-xhx9pzhj 1320 2 ( ( -LRB- cord-005646-xhx9pzhj 1320 3 toxic toxic JJ cord-005646-xhx9pzhj 1320 4 threshold threshold NN cord-005646-xhx9pzhj 1320 5 = = NFP cord-005646-xhx9pzhj 1321 1 50gruel 50gruel CD cord-005646-xhx9pzhj 1321 2 / / SYM cord-005646-xhx9pzhj 1321 3 f f NN cord-005646-xhx9pzhj 1321 4 ) ) -RRB- cord-005646-xhx9pzhj 1321 5 . . . cord-005646-xhx9pzhj 1322 1 The the DT cord-005646-xhx9pzhj 1322 2 plasma plasma NN cord-005646-xhx9pzhj 1322 3 fluoride fluoride NN cord-005646-xhx9pzhj 1322 4 positively positively RB cord-005646-xhx9pzhj 1322 5 co;related co;relate VBD cord-005646-xhx9pzhj 1322 6 with with IN cord-005646-xhx9pzhj 1322 7 the the DT cord-005646-xhx9pzhj 1322 8 % % NN cord-005646-xhx9pzhj 1322 9 -hours -hour NNS cord-005646-xhx9pzhj 1322 10 of of IN cord-005646-xhx9pzhj 1322 11 isoflurane isoflurane NNP cord-005646-xhx9pzhj 1322 12 ( ( -LRB- cord-005646-xhx9pzhj 1322 13 r r NN cord-005646-xhx9pzhj 1322 14 = = SYM cord-005646-xhx9pzhj 1322 15 0.65 0.65 CD cord-005646-xhx9pzhj 1322 16 , , , cord-005646-xhx9pzhj 1322 17 p p NN cord-005646-xhx9pzhj 1322 18 = = SYM cord-005646-xhx9pzhj 1322 19 < < XX cord-005646-xhx9pzhj 1322 20 0.001 0.001 CD cord-005646-xhx9pzhj 1322 21 ) ) -RRB- cord-005646-xhx9pzhj 1322 22 . . . cord-005646-xhx9pzhj 1323 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1323 2 : : : cord-005646-xhx9pzhj 1324 1 This this DT cord-005646-xhx9pzhj 1324 2 study study NN cord-005646-xhx9pzhj 1324 3 shows show VBZ cord-005646-xhx9pzhj 1324 4 that that IN cord-005646-xhx9pzhj 1324 5 although although IN cord-005646-xhx9pzhj 1324 6 there there EX cord-005646-xhx9pzhj 1324 7 is be VBZ cord-005646-xhx9pzhj 1324 8 a a DT cord-005646-xhx9pzhj 1324 9 dose dose NN cord-005646-xhx9pzhj 1324 10 related relate VBN cord-005646-xhx9pzhj 1324 11 accumulation accumulation NN cord-005646-xhx9pzhj 1324 12 of of IN cord-005646-xhx9pzhj 1324 13 inorganic inorganic JJ cord-005646-xhx9pzhj 1324 14 fluoride fluoride NN cord-005646-xhx9pzhj 1324 15 ions ion NNS cord-005646-xhx9pzhj 1324 16 in in IN cord-005646-xhx9pzhj 1324 17 patients patient NNS cord-005646-xhx9pzhj 1324 18 sedated sedate VBN cord-005646-xhx9pzhj 1324 19 with with IN cord-005646-xhx9pzhj 1324 20 isoflurane isoflurane NNS cord-005646-xhx9pzhj 1324 21 on on IN cord-005646-xhx9pzhj 1324 22 ECMQ ECMQ NNP cord-005646-xhx9pzhj 1324 23 , , , cord-005646-xhx9pzhj 1324 24 the the DT cord-005646-xhx9pzhj 1324 25 peak peak NN cord-005646-xhx9pzhj 1324 26 fluoride fluoride NN cord-005646-xhx9pzhj 1324 27 levels level NNS cord-005646-xhx9pzhj 1324 28 are be VBP cord-005646-xhx9pzhj 1324 29 well well RB cord-005646-xhx9pzhj 1324 30 below below IN cord-005646-xhx9pzhj 1324 31 the the DT cord-005646-xhx9pzhj 1324 32 suggested suggest VBN cord-005646-xhx9pzhj 1324 33 toxic toxic JJ cord-005646-xhx9pzhj 1324 34 threshold threshold NN cord-005646-xhx9pzhj 1324 35 . . . cord-005646-xhx9pzhj 1325 1 Merzel Merzel NNP cord-005646-xhx9pzhj 1325 2 Y Y NNP cord-005646-xhx9pzhj 1325 3 , , , cord-005646-xhx9pzhj 1325 4 Lev Lev NNP cord-005646-xhx9pzhj 1325 5 A A NNP cord-005646-xhx9pzhj 1325 6 , , , cord-005646-xhx9pzhj 1325 7 Bar Bar NNP cord-005646-xhx9pzhj 1325 8 Yosef Yosef NNP cord-005646-xhx9pzhj 1325 9 G G NNP cord-005646-xhx9pzhj 1325 10 , , , cord-005646-xhx9pzhj 1325 11 Halbertal Halbertal NNP cord-005646-xhx9pzhj 1325 12 M M NNP cord-005646-xhx9pzhj 1325 13 , , , cord-005646-xhx9pzhj 1325 14 Lorber Lorber NNP cord-005646-xhx9pzhj 1325 15 A A NNP cord-005646-xhx9pzhj 1325 16 ECMO ECMO NNP cord-005646-xhx9pzhj 1325 17 Center Center NNP cord-005646-xhx9pzhj 1325 18 , , , cord-005646-xhx9pzhj 1325 19 PICU PICU NNP cord-005646-xhx9pzhj 1325 20 , , , cord-005646-xhx9pzhj 1325 21 Emek Emek NNP cord-005646-xhx9pzhj 1325 22 Medical Medical NNP cord-005646-xhx9pzhj 1325 23 Center Center NNP cord-005646-xhx9pzhj 1325 24 , , , cord-005646-xhx9pzhj 1325 25 Israel Israel NNP cord-005646-xhx9pzhj 1325 26 . . . cord-005646-xhx9pzhj 1326 1 The the DT cord-005646-xhx9pzhj 1326 2 mortality mortality NN cord-005646-xhx9pzhj 1326 3 rate rate NN cord-005646-xhx9pzhj 1326 4 of of IN cord-005646-xhx9pzhj 1326 5 pediatric pediatric JJ cord-005646-xhx9pzhj 1326 6 patients patient NNS cord-005646-xhx9pzhj 1326 7 with with IN cord-005646-xhx9pzhj 1326 8 acute acute JJ cord-005646-xhx9pzhj 1326 9 myocarditis myocarditis NN cord-005646-xhx9pzhj 1326 10 is be VBZ cord-005646-xhx9pzhj 1326 11 20 20 CD cord-005646-xhx9pzhj 1326 12 - - SYM cord-005646-xhx9pzhj 1326 13 60 60 CD cord-005646-xhx9pzhj 1326 14 % % NN cord-005646-xhx9pzhj 1326 15 according accord VBG cord-005646-xhx9pzhj 1326 16 to to IN cord-005646-xhx9pzhj 1326 17 the the DT cord-005646-xhx9pzhj 1326 18 severity severity NN cord-005646-xhx9pzhj 1326 19 of of IN cord-005646-xhx9pzhj 1326 20 myocardial myocardial JJ cord-005646-xhx9pzhj 1326 21 damage damage NN cord-005646-xhx9pzhj 1326 22 . . . cord-005646-xhx9pzhj 1327 1 A a DT cord-005646-xhx9pzhj 1327 2 15 15 CD cord-005646-xhx9pzhj 1327 3 month month NN cord-005646-xhx9pzhj 1327 4 old old JJ cord-005646-xhx9pzhj 1327 5 gzrl gzrl NNP cord-005646-xhx9pzhj 1327 6 presented present VBN cord-005646-xhx9pzhj 1327 7 with with IN cord-005646-xhx9pzhj 1327 8 high high JJ cord-005646-xhx9pzhj 1327 9 fever fever NN cord-005646-xhx9pzhj 1327 10 , , , cord-005646-xhx9pzhj 1327 11 respiratory respiratory JJ cord-005646-xhx9pzhj 1327 12 and and CC cord-005646-xhx9pzhj 1327 13 cardiac cardiac JJ cord-005646-xhx9pzhj 1327 14 failure failure NN cord-005646-xhx9pzhj 1327 15 . . . cord-005646-xhx9pzhj 1328 1 Diagnosis diagnosis NN cord-005646-xhx9pzhj 1328 2 of of IN cord-005646-xhx9pzhj 1328 3 acute acute JJ cord-005646-xhx9pzhj 1328 4 myocarditis myocarditis NN cord-005646-xhx9pzhj 1328 5 was be VBD cord-005646-xhx9pzhj 1328 6 made make VBN cord-005646-xhx9pzhj 1328 7 and and CC cord-005646-xhx9pzhj 1328 8 the the DT cord-005646-xhx9pzhj 1328 9 patient patient NN cord-005646-xhx9pzhj 1328 10 was be VBD cord-005646-xhx9pzhj 1328 11 ventilated ventilate VBN cord-005646-xhx9pzhj 1328 12 with with IN cord-005646-xhx9pzhj 1328 13 high high JJ cord-005646-xhx9pzhj 1328 14 pressures pressure NNS cord-005646-xhx9pzhj 1328 15 and and CC cord-005646-xhx9pzhj 1328 16 FIO2 FIO2 NNP cord-005646-xhx9pzhj 1328 17 of of IN cord-005646-xhx9pzhj 1328 18 1.0 1.0 CD cord-005646-xhx9pzhj 1328 19 . . . cord-005646-xhx9pzhj 1329 1 She -PRON- PRP cord-005646-xhx9pzhj 1329 2 required require VBD cord-005646-xhx9pzhj 1329 3 high high JJ cord-005646-xhx9pzhj 1329 4 doses dose NNS cord-005646-xhx9pzhj 1329 5 of of IN cord-005646-xhx9pzhj 1329 6 inotropes inotrope NNS cord-005646-xhx9pzhj 1329 7 . . . cord-005646-xhx9pzhj 1330 1 Echocardiography echocardiography NN cord-005646-xhx9pzhj 1330 2 revealed reveal VBD cord-005646-xhx9pzhj 1330 3 a a DT cord-005646-xhx9pzhj 1330 4 dilated dilated JJ cord-005646-xhx9pzhj 1330 5 LA LA NNP cord-005646-xhx9pzhj 1330 6 and and CC cord-005646-xhx9pzhj 1330 7 LV LV NNP cord-005646-xhx9pzhj 1330 8 with with IN cord-005646-xhx9pzhj 1330 9 severe severe JJ cord-005646-xhx9pzhj 1330 10 MR MR NNP cord-005646-xhx9pzhj 1330 11 . . . cord-005646-xhx9pzhj 1331 1 LVEDD LVEDD NNP cord-005646-xhx9pzhj 1331 2 was be VBD cord-005646-xhx9pzhj 1331 3 41 41 CD cord-005646-xhx9pzhj 1331 4 mm mm NNS cord-005646-xhx9pzhj 1331 5 and and CC cord-005646-xhx9pzhj 1331 6 LVSF LVSF NNP cord-005646-xhx9pzhj 1331 7 9 9 CD cord-005646-xhx9pzhj 1331 8 % % NN cord-005646-xhx9pzhj 1331 9 . . . cord-005646-xhx9pzhj 1332 1 Calculated calculated JJ cord-005646-xhx9pzhj 1332 2 oxygenation oxygenation NN cord-005646-xhx9pzhj 1332 3 index index NN cord-005646-xhx9pzhj 1332 4 was be VBD cord-005646-xhx9pzhj 1332 5 55 55 CD cord-005646-xhx9pzhj 1332 6 . . . cord-005646-xhx9pzhj 1333 1 She -PRON- PRP cord-005646-xhx9pzhj 1333 2 was be VBD cord-005646-xhx9pzhj 1333 3 resuscitated resuscitate VBN cord-005646-xhx9pzhj 1333 4 after after IN cord-005646-xhx9pzhj 1333 5 a a DT cord-005646-xhx9pzhj 1333 6 cardiac cardiac JJ cord-005646-xhx9pzhj 1333 7 arrest arrest NN cord-005646-xhx9pzhj 1333 8 . . . cord-005646-xhx9pzhj 1334 1 She -PRON- PRP cord-005646-xhx9pzhj 1334 2 was be VBD cord-005646-xhx9pzhj 1334 3 commenced commence VBN cord-005646-xhx9pzhj 1334 4 on on IN cord-005646-xhx9pzhj 1334 5 ECMO ECMO NNP cord-005646-xhx9pzhj 1334 6 ( ( -LRB- cord-005646-xhx9pzhj 1334 7 using use VBG cord-005646-xhx9pzhj 1334 8 Biomedicus Biomedicus NNP cord-005646-xhx9pzhj 1334 9 centrifugal centrifugal JJ cord-005646-xhx9pzhj 1334 10 pump pump NN cord-005646-xhx9pzhj 1334 11 and and CC cord-005646-xhx9pzhj 1334 12 Avecor Avecor NNP cord-005646-xhx9pzhj 1334 13 800 800 CD cord-005646-xhx9pzhj 1334 14 oxygenator oxygenator NN cord-005646-xhx9pzhj 1334 15 ) ) -RRB- cord-005646-xhx9pzhj 1334 16 at at IN cord-005646-xhx9pzhj 1334 17 a a DT cord-005646-xhx9pzhj 1334 18 flow flow NN cord-005646-xhx9pzhj 1334 19 of of IN cord-005646-xhx9pzhj 1334 20 100 100 CD cord-005646-xhx9pzhj 1334 21 ml ml NNS cord-005646-xhx9pzhj 1334 22 / / SYM cord-005646-xhx9pzhj 1334 23 kg kg NNP cord-005646-xhx9pzhj 1334 24 / / SYM cord-005646-xhx9pzhj 1334 25 mm mm NN cord-005646-xhx9pzhj 1334 26 with with IN cord-005646-xhx9pzhj 1334 27 immediate immediate JJ cord-005646-xhx9pzhj 1334 28 improvement improvement NN cord-005646-xhx9pzhj 1334 29 of of IN cord-005646-xhx9pzhj 1334 30 hemodynamlcs hemodynamlcs NN cord-005646-xhx9pzhj 1334 31 , , , cord-005646-xhx9pzhj 1334 32 oxygenation oxygenation NN cord-005646-xhx9pzhj 1334 33 and and CC cord-005646-xhx9pzhj 1334 34 pC02 pc02 NN cord-005646-xhx9pzhj 1334 35 . . . cord-005646-xhx9pzhj 1335 1 Resptratory resptratory JJ cord-005646-xhx9pzhj 1335 2 assistance assistance NN cord-005646-xhx9pzhj 1335 3 and and CC cord-005646-xhx9pzhj 1335 4 vasoactive vasoactive JJ cord-005646-xhx9pzhj 1335 5 drugs drug NNS cord-005646-xhx9pzhj 1335 6 were be VBD cord-005646-xhx9pzhj 1335 7 reduced reduce VBN cord-005646-xhx9pzhj 1335 8 . . . cord-005646-xhx9pzhj 1336 1 The the DT cord-005646-xhx9pzhj 1336 2 patient patient NN cord-005646-xhx9pzhj 1336 3 was be VBD cord-005646-xhx9pzhj 1336 4 transported transport VBN cord-005646-xhx9pzhj 1336 5 by by IN cord-005646-xhx9pzhj 1336 6 air air NN cord-005646-xhx9pzhj 1336 7 , , , cord-005646-xhx9pzhj 1336 8 on on IN cord-005646-xhx9pzhj 1336 9 ECMO ECMO NNP cord-005646-xhx9pzhj 1336 10 , , , cord-005646-xhx9pzhj 1336 11 to to IN cord-005646-xhx9pzhj 1336 12 the the DT cord-005646-xhx9pzhj 1336 13 ECMO ECMO NNP cord-005646-xhx9pzhj 1336 14 cevter cevter NN cord-005646-xhx9pzhj 1336 15 . . . cord-005646-xhx9pzhj 1337 1 She -PRON- PRP cord-005646-xhx9pzhj 1337 2 developed develop VBD cord-005646-xhx9pzhj 1337 3 ARF arf NN cord-005646-xhx9pzhj 1337 4 and and CC cord-005646-xhx9pzhj 1337 5 CVVH CVVH NNP cord-005646-xhx9pzhj 1337 6 - - HYPH cord-005646-xhx9pzhj 1337 7 D D NNP cord-005646-xhx9pzhj 1337 8 was be VBD cord-005646-xhx9pzhj 1337 9 performed perform VBN cord-005646-xhx9pzhj 1337 10 . . . cord-005646-xhx9pzhj 1338 1 Cardiac cardiac JJ cord-005646-xhx9pzhj 1338 2 fimction fimction NN cord-005646-xhx9pzhj 1338 3 started start VBD cord-005646-xhx9pzhj 1338 4 to to TO cord-005646-xhx9pzhj 1338 5 improve improve VB cord-005646-xhx9pzhj 1338 6 after after IN cord-005646-xhx9pzhj 1338 7 12 12 CD cord-005646-xhx9pzhj 1338 8 days day NNS cord-005646-xhx9pzhj 1338 9 . . . cord-005646-xhx9pzhj 1339 1 ECMO ECMO NNP cord-005646-xhx9pzhj 1339 2 was be VBD cord-005646-xhx9pzhj 1339 3 discontinued discontinue VBN cord-005646-xhx9pzhj 1339 4 on on IN cord-005646-xhx9pzhj 1339 5 day day NN cord-005646-xhx9pzhj 1339 6 18 18 CD cord-005646-xhx9pzhj 1339 7 . . . cord-005646-xhx9pzhj 1340 1 Echo Echo NNP cord-005646-xhx9pzhj 1340 2 revealed reveal VBD cord-005646-xhx9pzhj 1340 3 LVEDD LVEDD NNP cord-005646-xhx9pzhj 1340 4 34 34 CD cord-005646-xhx9pzhj 1340 5 mm mm NNP cord-005646-xhx9pzhj 1340 6 and and CC cord-005646-xhx9pzhj 1340 7 LVSF LVSF NNP cord-005646-xhx9pzhj 1340 8 24 24 CD cord-005646-xhx9pzhj 1340 9 % % NN cord-005646-xhx9pzhj 1340 10 . . . cord-005646-xhx9pzhj 1341 1 IPPV IPPV NNP cord-005646-xhx9pzhj 1341 2 was be VBD cord-005646-xhx9pzhj 1341 3 discontinued discontinue VBN cord-005646-xhx9pzhj 1341 4 on on IN cord-005646-xhx9pzhj 1341 5 day day NN cord-005646-xhx9pzhj 1341 6 20 20 CD cord-005646-xhx9pzhj 1341 7 . . . cord-005646-xhx9pzhj 1342 1 On on IN cord-005646-xhx9pzhj 1342 2 discharge discharge NN cord-005646-xhx9pzhj 1342 3 , , , cord-005646-xhx9pzhj 1342 4 a a DT cord-005646-xhx9pzhj 1342 5 month month NN cord-005646-xhx9pzhj 1342 6 later later RB cord-005646-xhx9pzhj 1342 7 , , , cord-005646-xhx9pzhj 1342 8 her -PRON- PRP$ cord-005646-xhx9pzhj 1342 9 LVEDD LVEDD NNP cord-005646-xhx9pzhj 1342 10 was be VBD cord-005646-xhx9pzhj 1342 11 29 29 CD cord-005646-xhx9pzhj 1342 12 mm mm NNS cord-005646-xhx9pzhj 1342 13 and and CC cord-005646-xhx9pzhj 1342 14 LVSF LVSF NNP cord-005646-xhx9pzhj 1342 15 28 28 CD cord-005646-xhx9pzhj 1342 16 % % NN cord-005646-xhx9pzhj 1342 17 . . . cord-005646-xhx9pzhj 1343 1 She -PRON- PRP cord-005646-xhx9pzhj 1343 2 behaves behave VBZ cord-005646-xhx9pzhj 1343 3 normally normally RB cord-005646-xhx9pzhj 1343 4 for for IN cord-005646-xhx9pzhj 1343 5 age age NN cord-005646-xhx9pzhj 1343 6 without without IN cord-005646-xhx9pzhj 1343 7 neurologic neurologic JJ cord-005646-xhx9pzhj 1343 8 or or CC cord-005646-xhx9pzhj 1343 9 other other JJ cord-005646-xhx9pzhj 1343 10 medical medical JJ cord-005646-xhx9pzhj 1343 11 sequellae sequellae NNS cord-005646-xhx9pzhj 1343 12 . . . cord-005646-xhx9pzhj 1344 1 Literature literature NN cord-005646-xhx9pzhj 1344 2 search search NN cord-005646-xhx9pzhj 1344 3 revealed reveal VBD cord-005646-xhx9pzhj 1344 4 no no DT cord-005646-xhx9pzhj 1344 5 case case NN cord-005646-xhx9pzhj 1344 6 of of IN cord-005646-xhx9pzhj 1344 7 acute acute JJ cord-005646-xhx9pzhj 1344 8 myocarditis myocarditis NN cord-005646-xhx9pzhj 1344 9 , , , cord-005646-xhx9pzhj 1344 10 as as IN cord-005646-xhx9pzhj 1344 11 severe severe JJ cord-005646-xhx9pzhj 1344 12 , , , cord-005646-xhx9pzhj 1344 13 that that WDT cord-005646-xhx9pzhj 1344 14 was be VBD cord-005646-xhx9pzhj 1344 15 treated treat VBN cord-005646-xhx9pzhj 1344 16 successfully successfully RB cord-005646-xhx9pzhj 1344 17 . . . cord-005646-xhx9pzhj 1345 1 Survavors survavor NNS cord-005646-xhx9pzhj 1345 2 of of IN cord-005646-xhx9pzhj 1345 3 disease disease NN cord-005646-xhx9pzhj 1345 4 this this DT cord-005646-xhx9pzhj 1345 5 severe severe JJ cord-005646-xhx9pzhj 1345 6 usually usually RB cord-005646-xhx9pzhj 1345 7 suffer suffer VBP cord-005646-xhx9pzhj 1345 8 dilated dilated JJ cord-005646-xhx9pzhj 1345 9 cardiomyopathy cardiomyopathy NN cord-005646-xhx9pzhj 1345 10 and and CC cord-005646-xhx9pzhj 1345 11 permanent permanent JJ cord-005646-xhx9pzhj 1345 12 disability disability NN cord-005646-xhx9pzhj 1345 13 . . . cord-005646-xhx9pzhj 1346 1 The the DT cord-005646-xhx9pzhj 1346 2 use use NN cord-005646-xhx9pzhj 1346 3 of of IN cord-005646-xhx9pzhj 1346 4 ECMO ECMO NNP cord-005646-xhx9pzhj 1346 5 allows allow VBZ cord-005646-xhx9pzhj 1346 6 myocardial myocardial JJ cord-005646-xhx9pzhj 1346 7 rest rest NN cord-005646-xhx9pzhj 1346 8 which which WDT cord-005646-xhx9pzhj 1346 9 prevents prevent VBZ cord-005646-xhx9pzhj 1346 10 long long JJ cord-005646-xhx9pzhj 1346 11 term term NN cord-005646-xhx9pzhj 1346 12 myocardial myocardial JJ cord-005646-xhx9pzhj 1346 13 damage damage NN cord-005646-xhx9pzhj 1346 14 . . . cord-005646-xhx9pzhj 1347 1 Introduction introduction NN cord-005646-xhx9pzhj 1347 2 ECMO ECMO NNP cord-005646-xhx9pzhj 1347 3 is be VBZ cord-005646-xhx9pzhj 1347 4 increasingly increasingly RB cord-005646-xhx9pzhj 1347 5 used use VBN cord-005646-xhx9pzhj 1347 6 in in IN cord-005646-xhx9pzhj 1347 7 the the DT cord-005646-xhx9pzhj 1347 8 care care NN cord-005646-xhx9pzhj 1347 9 of of IN cord-005646-xhx9pzhj 1347 10 critically critically RB cord-005646-xhx9pzhj 1347 11 ill ill JJ cord-005646-xhx9pzhj 1347 12 newborns newborn NNS cord-005646-xhx9pzhj 1347 13 . . . cord-005646-xhx9pzhj 1348 1 Despite despite IN cord-005646-xhx9pzhj 1348 2 the the DT cord-005646-xhx9pzhj 1348 3 frequent frequent JJ cord-005646-xhx9pzhj 1348 4 use use NN cord-005646-xhx9pzhj 1348 5 of of IN cord-005646-xhx9pzhj 1348 6 betalactam betalactam NNP cord-005646-xhx9pzhj 1348 7 antibiotics antibiotic NNS cord-005646-xhx9pzhj 1348 8 in in IN cord-005646-xhx9pzhj 1348 9 the the DT cord-005646-xhx9pzhj 1348 10 treatment treatment NN cord-005646-xhx9pzhj 1348 11 of of IN cord-005646-xhx9pzhj 1348 12 these these DT cord-005646-xhx9pzhj 1348 13 infants infant NNS cord-005646-xhx9pzhj 1348 14 there there EX cord-005646-xhx9pzhj 1348 15 are be VBP cord-005646-xhx9pzhj 1348 16 no no DT cord-005646-xhx9pzhj 1348 17 data datum NNS cord-005646-xhx9pzhj 1348 18 available available JJ cord-005646-xhx9pzhj 1348 19 on on IN cord-005646-xhx9pzhj 1348 20 the the DT cord-005646-xhx9pzhj 1348 21 dispbsition dispbsition NN cord-005646-xhx9pzhj 1348 22 of of IN cord-005646-xhx9pzhj 1348 23 cefotaxime cefotaxime NNP cord-005646-xhx9pzhj 1348 24 ( ( -LRB- cord-005646-xhx9pzhj 1348 25 CTX CTX NNP cord-005646-xhx9pzhj 1348 26 ) ) -RRB- cord-005646-xhx9pzhj 1348 27 and and CC cord-005646-xhx9pzhj 1348 28 amoxicilfin amoxicilfin NNP cord-005646-xhx9pzhj 1348 29 ( ( -LRB- cord-005646-xhx9pzhj 1348 30 AM AM NNP cord-005646-xhx9pzhj 1348 31 ) ) -RRB- cord-005646-xhx9pzhj 1349 1 d0ring d0ring NNP cord-005646-xhx9pzhj 1349 2 ECMO ECMO NNP cord-005646-xhx9pzhj 1349 3 . . . cord-005646-xhx9pzhj 1350 1 The the DT cord-005646-xhx9pzhj 1350 2 purposes purpose NNS cord-005646-xhx9pzhj 1350 3 of of IN cord-005646-xhx9pzhj 1350 4 this this DT cord-005646-xhx9pzhj 1350 5 study study NN cord-005646-xhx9pzhj 1350 6 were be VBD cord-005646-xhx9pzhj 1350 7 to to TO cord-005646-xhx9pzhj 1350 8 determine determine VB cord-005646-xhx9pzhj 1350 9 the the DT cord-005646-xhx9pzhj 1350 10 pharmacokinetics pharmacokinetic NNS cord-005646-xhx9pzhj 1350 11 of of IN cord-005646-xhx9pzhj 1350 12 these these DT cord-005646-xhx9pzhj 1350 13 two two CD cord-005646-xhx9pzhj 1350 14 drugs drug NNS cord-005646-xhx9pzhj 1350 15 in in IN cord-005646-xhx9pzhj 1350 16 infants infant NNS cord-005646-xhx9pzhj 1350 17 on on IN cord-005646-xhx9pzhj 1350 18 ECMO ECMO NNP cord-005646-xhx9pzhj 1350 19 and and CC cord-005646-xhx9pzhj 1350 20 consequently consequently RB cord-005646-xhx9pzhj 1350 21 formulate formulate VB cord-005646-xhx9pzhj 1350 22 appropriate appropriate JJ cord-005646-xhx9pzhj 1350 23 dosing dose VBG cord-005646-xhx9pzhj 1350 24 regimens regimen NNS cord-005646-xhx9pzhj 1350 25 . . . cord-005646-xhx9pzhj 1351 1 We -PRON- PRP cord-005646-xhx9pzhj 1351 2 therefore therefore RB cord-005646-xhx9pzhj 1351 3 studied study VBD cord-005646-xhx9pzhj 1351 4 the the DT cord-005646-xhx9pzhj 1351 5 pharmacokinetics pharmacokinetic NNS cord-005646-xhx9pzhj 1351 6 of of IN cord-005646-xhx9pzhj 1351 7 CTX CTX NNP cord-005646-xhx9pzhj 1351 8 ( ( -LRB- cord-005646-xhx9pzhj 1351 9 100 100 CD cord-005646-xhx9pzhj 1351 10 mg mg NNP cord-005646-xhx9pzhj 1351 11 / / SYM cord-005646-xhx9pzhj 1351 12 kg kg NNP cord-005646-xhx9pzhj 1352 1 ql ql NNP cord-005646-xhx9pzhj 1352 2 2h 2h NNP cord-005646-xhx9pzhj 1352 3 ) ) -RRB- cord-005646-xhx9pzhj 1352 4 and and CC cord-005646-xhx9pzhj 1352 5 AM AM NNP cord-005646-xhx9pzhj 1352 6 ( ( -LRB- cord-005646-xhx9pzhj 1352 7 50 50 CD cord-005646-xhx9pzhj 1352 8 mg mg NNP cord-005646-xhx9pzhj 1352 9 / / SYM cord-005646-xhx9pzhj 1352 10 kg kg NNP cord-005646-xhx9pzhj 1352 11 q6h q6h NNP cord-005646-xhx9pzhj 1352 12 ) ) -RRB- cord-005646-xhx9pzhj 1352 13 in in IN cord-005646-xhx9pzhj 1352 14 8 8 CD cord-005646-xhx9pzhj 1352 15 term term NN cord-005646-xhx9pzhj 1352 16 infants infant NNS cord-005646-xhx9pzhj 1352 17 on on IN cord-005646-xhx9pzhj 1352 18 day day NN cord-005646-xhx9pzhj 1352 19 3 3 CD cord-005646-xhx9pzhj 1352 20 after after IN cord-005646-xhx9pzhj 1352 21 birth birth NN cord-005646-xhx9pzhj 1353 1 , , , cord-005646-xhx9pzhj 1353 2 Blood blood NN cord-005646-xhx9pzhj 1353 3 samples sample NNS cord-005646-xhx9pzhj 1353 4 were be VBD cord-005646-xhx9pzhj 1353 5 taken take VBN cord-005646-xhx9pzhj 1353 6 before before RB cord-005646-xhx9pzhj 1353 7 ( ( -LRB- cord-005646-xhx9pzhj 1353 8 t t NN cord-005646-xhx9pzhj 1353 9 - - HYPH cord-005646-xhx9pzhj 1353 10 O O NNP cord-005646-xhx9pzhj 1353 11 ) ) -RRB- cord-005646-xhx9pzhj 1353 12 and and CC cord-005646-xhx9pzhj 1353 13 0.5,1,2,4,6 0.5,1,2,4,6 LS cord-005646-xhx9pzhj 1353 14 ( ( -LRB- cord-005646-xhx9pzhj 1353 15 AM AM NNP cord-005646-xhx9pzhj 1353 16 ) ) -RRB- cord-005646-xhx9pzhj 1353 17 and and CC cord-005646-xhx9pzhj 1353 18 t2 t2 NNP cord-005646-xhx9pzhj 1353 19 h h NNP cord-005646-xhx9pzhj 1353 20 ( ( -LRB- cord-005646-xhx9pzhj 1353 21 CTX CTX NNP cord-005646-xhx9pzhj 1353 22 ) ) -RRB- cord-005646-xhx9pzhj 1353 23 after after IN cord-005646-xhx9pzhj 1353 24 the the DT cord-005646-xhx9pzhj 1353 25 intravenous intravenous JJ cord-005646-xhx9pzhj 1353 26 bolus bolus NN cord-005646-xhx9pzhj 1353 27 injection injection NN cord-005646-xhx9pzhj 1353 28 and and CC cord-005646-xhx9pzhj 1353 29 analyzed analyze VBN cord-005646-xhx9pzhj 1353 30 by by IN cord-005646-xhx9pzhj 1353 31 HPLC HPLC NNP cord-005646-xhx9pzhj 1353 32 - - HYPH cord-005646-xhx9pzhj 1353 33 assays assay NNS cord-005646-xhx9pzhj 1353 34 . . . cord-005646-xhx9pzhj 1354 1 2 2 LS cord-005646-xhx9pzhj 1354 2 . . . cord-005646-xhx9pzhj 1355 1 CTX CTX NNP cord-005646-xhx9pzhj 1355 2 100 100 CD cord-005646-xhx9pzhj 1356 1 mg mg NNP cord-005646-xhx9pzhj 1356 2 / / SYM cord-005646-xhx9pzhj 1356 3 kg kg NNP cord-005646-xhx9pzhj 1357 1 q12h q12h NFP cord-005646-xhx9pzhj 1357 2 results result NNS cord-005646-xhx9pzhj 1357 3 in in IN cord-005646-xhx9pzhj 1357 4 adequate adequate JJ cord-005646-xhx9pzhj 1357 5 serum serum NN cord-005646-xhx9pzhj 1357 6 levels level NNS cord-005646-xhx9pzhj 1357 7 of of IN cord-005646-xhx9pzhj 1357 8 CTX CTX NNP cord-005646-xhx9pzhj 1357 9 in in IN cord-005646-xhx9pzhj 1357 10 fullterm fullterm JJ cord-005646-xhx9pzhj 1357 11 infants infant NNS cord-005646-xhx9pzhj 1357 12 on on IN cord-005646-xhx9pzhj 1357 13 ECMO ECMO NNP cord-005646-xhx9pzhj 1358 1 , , , cord-005646-xhx9pzhj 1358 2 AM AM NNP cord-005646-xhx9pzhj 1358 3 50 50 CD cord-005646-xhx9pzhj 1359 1 mg mg NNP cord-005646-xhx9pzhj 1359 2 / / SYM cord-005646-xhx9pzhj 1359 3 kg kg NNP cord-005646-xhx9pzhj 1359 4 q6h q6h NNP cord-005646-xhx9pzhj 1359 5 results result NNS cord-005646-xhx9pzhj 1359 6 in in IN cord-005646-xhx9pzhj 1359 7 very very RB cord-005646-xhx9pzhj 1359 8 high high JJ cord-005646-xhx9pzhj 1359 9 serum serum NN cord-005646-xhx9pzhj 1359 10 trough trough NN cord-005646-xhx9pzhj 1359 11 levels level NNS cord-005646-xhx9pzhj 1359 12 . . . cord-005646-xhx9pzhj 1360 1 Recalculation recalculation NN cord-005646-xhx9pzhj 1360 2 based base VBN cord-005646-xhx9pzhj 1360 3 on on IN cord-005646-xhx9pzhj 1360 4 the the DT cord-005646-xhx9pzhj 1360 5 known know VBN cord-005646-xhx9pzhj 1360 6 volume volume NN cord-005646-xhx9pzhj 1360 7 of of IN cord-005646-xhx9pzhj 1360 8 distribution distribution NN cord-005646-xhx9pzhj 1360 9 and and CC cord-005646-xhx9pzhj 1360 10 elimination elimination NN cord-005646-xhx9pzhj 1360 11 serum serum NN cord-005646-xhx9pzhj 1360 12 half half JJ cord-005646-xhx9pzhj 1360 13 - - HYPH cord-005646-xhx9pzhj 1360 14 life life NN cord-005646-xhx9pzhj 1360 15 of of IN cord-005646-xhx9pzhj 1360 16 these these DT cord-005646-xhx9pzhj 1360 17 infants infant NNS cord-005646-xhx9pzhj 1360 18 resulted result VBD cord-005646-xhx9pzhj 1360 19 in in IN cord-005646-xhx9pzhj 1360 20 the the DT cord-005646-xhx9pzhj 1360 21 following follow VBG cord-005646-xhx9pzhj 1360 22 dosage dosage NN cord-005646-xhx9pzhj 1360 23 recommendation recommendation NN cord-005646-xhx9pzhj 1360 24 : : : cord-005646-xhx9pzhj 1360 25 50 50 CD cord-005646-xhx9pzhj 1360 26 mg mg NNP cord-005646-xhx9pzhj 1360 27 / / SYM cord-005646-xhx9pzhj 1360 28 kg kg NNP cord-005646-xhx9pzhj 1360 29 q12h q12h ADD cord-005646-xhx9pzhj 1360 30 . . . cord-005646-xhx9pzhj 1361 1 Persistent persistent JJ cord-005646-xhx9pzhj 1361 2 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1361 3 hypertension hypertension NN cord-005646-xhx9pzhj 1361 4 of of IN cord-005646-xhx9pzhj 1361 5 the the DT cord-005646-xhx9pzhj 1361 6 new new RB cord-005646-xhx9pzhj 1361 7 - - HYPH cord-005646-xhx9pzhj 1361 8 born bear VBN cord-005646-xhx9pzhj 1361 9 ( ( -LRB- cord-005646-xhx9pzhj 1361 10 PPHN PPHN NNP cord-005646-xhx9pzhj 1361 11 ) ) -RRB- cord-005646-xhx9pzhj 1361 12 is be VBZ cord-005646-xhx9pzhj 1361 13 characterised characterise VBN cord-005646-xhx9pzhj 1361 14 by by IN cord-005646-xhx9pzhj 1361 15 rapid rapid JJ cord-005646-xhx9pzhj 1361 16 fluctuations fluctuation NNS cord-005646-xhx9pzhj 1361 17 in in IN cord-005646-xhx9pzhj 1361 18 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1361 19 artery artery NN cord-005646-xhx9pzhj 1361 20 pressure pressure NN cord-005646-xhx9pzhj 1361 21 ( ( -LRB- cord-005646-xhx9pzhj 1361 22 PAP pap NN cord-005646-xhx9pzhj 1361 23 ) ) -RRB- cord-005646-xhx9pzhj 1361 24 and and CC cord-005646-xhx9pzhj 1361 25 a a DT cord-005646-xhx9pzhj 1361 26 clinical clinical JJ cord-005646-xhx9pzhj 1361 27 impression impression NN cord-005646-xhx9pzhj 1361 28 of of IN cord-005646-xhx9pzhj 1361 29 stifflungs stifflung NNS cord-005646-xhx9pzhj 1361 30 . . . cord-005646-xhx9pzhj 1362 1 Lung lung NN cord-005646-xhx9pzhj 1362 2 mechanics mechanic NNS cord-005646-xhx9pzhj 1362 3 were be VBD cord-005646-xhx9pzhj 1362 4 measured measure VBN cord-005646-xhx9pzhj 1362 5 in in IN cord-005646-xhx9pzhj 1362 6 35 35 CD cord-005646-xhx9pzhj 1362 7 term term NN cord-005646-xhx9pzhj 1362 8 infants infant NNS cord-005646-xhx9pzhj 1362 9 , , , cord-005646-xhx9pzhj 1362 10 mean mean VB cord-005646-xhx9pzhj 1362 11 age age NN cord-005646-xhx9pzhj 1362 12 1.5 1.5 CD cord-005646-xhx9pzhj 1363 1 + + CC cord-005646-xhx9pzhj 1363 2 _ _ NN cord-005646-xhx9pzhj 1363 3 0.7 0.7 CD cord-005646-xhx9pzhj 1363 4 days day NNS cord-005646-xhx9pzhj 1363 5 who who WP cord-005646-xhx9pzhj 1363 6 were be VBD cord-005646-xhx9pzhj 1363 7 paralysed paralyse VBN cord-005646-xhx9pzhj 1363 8 and and CC cord-005646-xhx9pzhj 1363 9 ventilated ventilate VBN cord-005646-xhx9pzhj 1363 10 within within IN cord-005646-xhx9pzhj 1363 11 the the DT cord-005646-xhx9pzhj 1363 12 first first JJ cord-005646-xhx9pzhj 1363 13 three three CD cord-005646-xhx9pzhj 1363 14 days day NNS cord-005646-xhx9pzhj 1363 15 of of IN cord-005646-xhx9pzhj 1363 16 life life NN cord-005646-xhx9pzhj 1363 17 . . . cord-005646-xhx9pzhj 1364 1 Fourteen fourteen CD cord-005646-xhx9pzhj 1364 2 infants infant NNS cord-005646-xhx9pzhj 1364 3 had have VBD cord-005646-xhx9pzhj 1364 4 PPHN PPHN NNS cord-005646-xhx9pzhj 1364 5 with with IN cord-005646-xhx9pzhj 1364 6 systemic systemic JJ cord-005646-xhx9pzhj 1364 7 or or CC cord-005646-xhx9pzhj 1364 8 suprasystemic suprasystemic JJ cord-005646-xhx9pzhj 1364 9 PAP pap NN cord-005646-xhx9pzhj 1364 10 measured measure VBN cord-005646-xhx9pzhj 1364 11 by by IN cord-005646-xhx9pzhj 1364 12 echocardiography echocardiography NN cord-005646-xhx9pzhj 1364 13 . . . cord-005646-xhx9pzhj 1365 1 In in IN cord-005646-xhx9pzhj 1365 2 these these DT cord-005646-xhx9pzhj 1365 3 patients patient NNS cord-005646-xhx9pzhj 1365 4 , , , cord-005646-xhx9pzhj 1365 5 the the DT cord-005646-xhx9pzhj 1365 6 respiratory respiratory JJ cord-005646-xhx9pzhj 1365 7 system system NN cord-005646-xhx9pzhj 1365 8 resistance resistance NN cord-005646-xhx9pzhj 1365 9 was be VBD cord-005646-xhx9pzhj 1365 10 29.4 29.4 CD cord-005646-xhx9pzhj 1365 11 % % NN cord-005646-xhx9pzhj 1365 12 higher high JJR cord-005646-xhx9pzhj 1365 13 ( ( -LRB- cord-005646-xhx9pzhj 1365 14 p p NN cord-005646-xhx9pzhj 1365 15 < < XX cord-005646-xhx9pzhj 1365 16 0.001 0.001 CD cord-005646-xhx9pzhj 1365 17 ) ) -RRB- cord-005646-xhx9pzhj 1365 18 and and CC cord-005646-xhx9pzhj 1365 19 compliance compliance NN cord-005646-xhx9pzhj 1365 20 22.4 22.4 CD cord-005646-xhx9pzhj 1365 21 % % NN cord-005646-xhx9pzhj 1365 22 lower low JJR cord-005646-xhx9pzhj 1366 1 ( ( -LRB- cord-005646-xhx9pzhj 1366 2 p p NN cord-005646-xhx9pzhj 1366 3 = = SYM cord-005646-xhx9pzhj 1366 4 0.03 0.03 CD cord-005646-xhx9pzhj 1366 5 ) ) -RRB- cord-005646-xhx9pzhj 1366 6 during during IN cord-005646-xhx9pzhj 1366 7 systemic systemic JJ cord-005646-xhx9pzhj 1366 8 or or CC cord-005646-xhx9pzhj 1366 9 suprasystemic suprasystemic JJ cord-005646-xhx9pzhj 1366 10 PAP pap NN cord-005646-xhx9pzhj 1366 11 compared compare VBN cord-005646-xhx9pzhj 1366 12 to to IN cord-005646-xhx9pzhj 1366 13 when when WRB cord-005646-xhx9pzhj 1366 14 the the DT cord-005646-xhx9pzhj 1366 15 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1366 16 hypertension hypertension NN cord-005646-xhx9pzhj 1366 17 had have VBD cord-005646-xhx9pzhj 1366 18 resolved resolve VBN cord-005646-xhx9pzhj 1366 19 . . . cord-005646-xhx9pzhj 1367 1 In in IN cord-005646-xhx9pzhj 1367 2 contrast contrast NN cord-005646-xhx9pzhj 1367 3 , , , cord-005646-xhx9pzhj 1367 4 there there EX cord-005646-xhx9pzhj 1367 5 were be VBD cord-005646-xhx9pzhj 1367 6 no no DT cord-005646-xhx9pzhj 1367 7 changes change NNS cord-005646-xhx9pzhj 1367 8 in in IN cord-005646-xhx9pzhj 1367 9 resistance resistance NN cord-005646-xhx9pzhj 1367 10 in in IN cord-005646-xhx9pzhj 1367 11 the the DT cord-005646-xhx9pzhj 1367 12 14 14 CD cord-005646-xhx9pzhj 1367 13 infants infant NNS cord-005646-xhx9pzhj 1367 14 with with IN cord-005646-xhx9pzhj 1367 15 respiratory respiratory JJ cord-005646-xhx9pzhj 1367 16 distress distress NN cord-005646-xhx9pzhj 1367 17 syndrome syndrome NN cord-005646-xhx9pzhj 1367 18 ( ( -LRB- cord-005646-xhx9pzhj 1367 19 RDS RDS NNP cord-005646-xhx9pzhj 1367 20 ) ) -RRB- cord-005646-xhx9pzhj 1367 21 and and CC cord-005646-xhx9pzhj 1367 22 no no DT cord-005646-xhx9pzhj 1367 23 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1367 24 hypertension hypertension NN cord-005646-xhx9pzhj 1367 25 or or CC cord-005646-xhx9pzhj 1367 26 in in IN cord-005646-xhx9pzhj 1367 27 the the DT cord-005646-xhx9pzhj 1367 28 seven seven CD cord-005646-xhx9pzhj 1367 29 infants infant NNS cord-005646-xhx9pzhj 1367 30 with with IN cord-005646-xhx9pzhj 1367 31 normal normal JJ cord-005646-xhx9pzhj 1367 32 lungs lung NNS cord-005646-xhx9pzhj 1367 33 , , , cord-005646-xhx9pzhj 1367 34 where where WRB cord-005646-xhx9pzhj 1367 35 two two CD cord-005646-xhx9pzhj 1367 36 readings reading NNS cord-005646-xhx9pzhj 1367 37 were be VBD cord-005646-xhx9pzhj 1367 38 taken take VBN cord-005646-xhx9pzhj 1367 39 24 24 CD cord-005646-xhx9pzhj 1367 40 hours hour NNS cord-005646-xhx9pzhj 1367 41 apart apart RB cord-005646-xhx9pzhj 1367 42 . . . cord-005646-xhx9pzhj 1368 1 The the DT cord-005646-xhx9pzhj 1368 2 changes change NNS cord-005646-xhx9pzhj 1368 3 in in IN cord-005646-xhx9pzhj 1368 4 lung lung NN cord-005646-xhx9pzhj 1368 5 mechanics mechanic NNS cord-005646-xhx9pzhj 1368 6 interfered interfere VBD cord-005646-xhx9pzhj 1368 7 with with IN cord-005646-xhx9pzhj 1368 8 mechanical mechanical JJ cord-005646-xhx9pzhj 1368 9 ventilation ventilation NN cord-005646-xhx9pzhj 1368 10 , , , cord-005646-xhx9pzhj 1368 11 resulting result VBG cord-005646-xhx9pzhj 1368 12 in in IN cord-005646-xhx9pzhj 1368 13 a a DT cord-005646-xhx9pzhj 1368 14 12.5 12.5 CD cord-005646-xhx9pzhj 1368 15 mmHg mmhg NN cord-005646-xhx9pzhj 1368 16 rise rise NN cord-005646-xhx9pzhj 1368 17 in in IN cord-005646-xhx9pzhj 1368 18 PaCO2 PaCO2 NNP cord-005646-xhx9pzhj 1368 19 ( ( -LRB- cord-005646-xhx9pzhj 1368 20 p=0.007 p=0.007 NNP cord-005646-xhx9pzhj 1368 21 ) ) -RRB- cord-005646-xhx9pzhj 1368 22 during during IN cord-005646-xhx9pzhj 1368 23 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1368 24 hypertension hypertension NN cord-005646-xhx9pzhj 1368 25 . . . cord-005646-xhx9pzhj 1369 1 Inhalation inhalation NN cord-005646-xhx9pzhj 1369 2 of of IN cord-005646-xhx9pzhj 1369 3 nitric nitric NN cord-005646-xhx9pzhj 1369 4 oxide oxide NN cord-005646-xhx9pzhj 1369 5 10 10 CD cord-005646-xhx9pzhj 1369 6 PPM ppm NN cord-005646-xhx9pzhj 1369 7 resulted result VBD cord-005646-xhx9pzhj 1369 8 in in IN cord-005646-xhx9pzhj 1369 9 a a DT cord-005646-xhx9pzhj 1369 10 16 16 CD cord-005646-xhx9pzhj 1369 11 % % NN cord-005646-xhx9pzhj 1369 12 decrease decrease NN cord-005646-xhx9pzhj 1369 13 in in IN cord-005646-xhx9pzhj 1369 14 respiratory respiratory JJ cord-005646-xhx9pzhj 1369 15 system system NN cord-005646-xhx9pzhj 1369 16 resistance resistance NN cord-005646-xhx9pzhj 1369 17 and and CC cord-005646-xhx9pzhj 1369 18 an an DT cord-005646-xhx9pzhj 1369 19 improvement improvement NN cord-005646-xhx9pzhj 1369 20 in in IN cord-005646-xhx9pzhj 1369 21 oxygenation oxygenation NN cord-005646-xhx9pzhj 1369 22 . . . cord-005646-xhx9pzhj 1370 1 The the DT cord-005646-xhx9pzhj 1370 2 bronchial bronchial JJ cord-005646-xhx9pzhj 1370 3 and and CC cord-005646-xhx9pzhj 1370 4 vascular vascular JJ cord-005646-xhx9pzhj 1370 5 smooth smooth JJ cord-005646-xhx9pzhj 1370 6 muscle muscle NN cord-005646-xhx9pzhj 1370 7 was be VBD cord-005646-xhx9pzhj 1370 8 increased increase VBN cord-005646-xhx9pzhj 1370 9 by by IN cord-005646-xhx9pzhj 1370 10 120 120 CD cord-005646-xhx9pzhj 1370 11 % % NN cord-005646-xhx9pzhj 1370 12 in in IN cord-005646-xhx9pzhj 1370 13 postmortem postmortem JJ cord-005646-xhx9pzhj 1370 14 lung lung NN cord-005646-xhx9pzhj 1370 15 samples sample NNS cord-005646-xhx9pzhj 1370 16 from from IN cord-005646-xhx9pzhj 1370 17 eight eight CD cord-005646-xhx9pzhj 1370 18 infants infant NNS cord-005646-xhx9pzhj 1370 19 with with IN cord-005646-xhx9pzhj 1370 20 PPHN PPHN NNS cord-005646-xhx9pzhj 1370 21 compared compare VBN cord-005646-xhx9pzhj 1370 22 to to IN cord-005646-xhx9pzhj 1370 23 six six CD cord-005646-xhx9pzhj 1370 24 age age NN cord-005646-xhx9pzhj 1370 25 matched match VBN cord-005646-xhx9pzhj 1370 26 post post JJ cord-005646-xhx9pzhj 1370 27 - - JJ cord-005646-xhx9pzhj 1370 28 mortem mortem JJ cord-005646-xhx9pzhj 1370 29 controls control NNS cord-005646-xhx9pzhj 1370 30 with with IN cord-005646-xhx9pzhj 1370 31 normal normal JJ cord-005646-xhx9pzhj 1370 32 lungs lung NNS cord-005646-xhx9pzhj 1370 33 ( ( -LRB- cord-005646-xhx9pzhj 1370 34 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 1370 35 ) ) -RRB- cord-005646-xhx9pzhj 1370 36 . . . cord-005646-xhx9pzhj 1371 1 These these DT cord-005646-xhx9pzhj 1371 2 findings finding NNS cord-005646-xhx9pzhj 1371 3 suggest suggest VBP cord-005646-xhx9pzhj 1371 4 a a DT cord-005646-xhx9pzhj 1371 5 co co NN cord-005646-xhx9pzhj 1371 6 - - NN cord-005646-xhx9pzhj 1371 7 constriction constriction NN cord-005646-xhx9pzhj 1371 8 and and CC cord-005646-xhx9pzhj 1371 9 co co NN cord-005646-xhx9pzhj 1371 10 - - NN cord-005646-xhx9pzhj 1371 11 hypertrophy hypertrophy NN cord-005646-xhx9pzhj 1371 12 of of IN cord-005646-xhx9pzhj 1371 13 bronchial bronchial JJ cord-005646-xhx9pzhj 1371 14 and and CC cord-005646-xhx9pzhj 1371 15 vascular vascular JJ cord-005646-xhx9pzhj 1371 16 smooth smooth JJ cord-005646-xhx9pzhj 1371 17 muscle muscle NN cord-005646-xhx9pzhj 1371 18 during during IN cord-005646-xhx9pzhj 1371 19 PPHN PPHN NNP cord-005646-xhx9pzhj 1371 20 . . . cord-005646-xhx9pzhj 1372 1 Anatomically anatomically RB cord-005646-xhx9pzhj 1372 2 the the DT cord-005646-xhx9pzhj 1372 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1372 4 vasculature vasculature NN cord-005646-xhx9pzhj 1372 5 and and CC cord-005646-xhx9pzhj 1372 6 bronchi bronchi NN cord-005646-xhx9pzhj 1372 7 lie lie NN cord-005646-xhx9pzhj 1372 8 in in IN cord-005646-xhx9pzhj 1372 9 close close JJ cord-005646-xhx9pzhj 1372 10 proximity proximity NN cord-005646-xhx9pzhj 1372 11 to to IN cord-005646-xhx9pzhj 1372 12 each each DT cord-005646-xhx9pzhj 1372 13 other other JJ cord-005646-xhx9pzhj 1372 14 . . . cord-005646-xhx9pzhj 1373 1 Thus thus RB cord-005646-xhx9pzhj 1373 2 mediators mediator NNS cord-005646-xhx9pzhj 1373 3 such such JJ cord-005646-xhx9pzhj 1373 4 as as IN cord-005646-xhx9pzhj 1373 5 Endothelin-1 Endothelin-1 NNP cord-005646-xhx9pzhj 1373 6 released release VBN cord-005646-xhx9pzhj 1373 7 locally locally RB cord-005646-xhx9pzhj 1373 8 may may MD cord-005646-xhx9pzhj 1373 9 act act VB cord-005646-xhx9pzhj 1373 10 on on IN cord-005646-xhx9pzhj 1373 11 both both CC cord-005646-xhx9pzhj 1373 12 vascular vascular JJ cord-005646-xhx9pzhj 1373 13 and and CC cord-005646-xhx9pzhj 1373 14 bronchial bronchial JJ cord-005646-xhx9pzhj 1373 15 smooth smooth JJ cord-005646-xhx9pzhj 1373 16 muscle muscle NN cord-005646-xhx9pzhj 1373 17 to to TO cord-005646-xhx9pzhj 1373 18 produce produce VB cord-005646-xhx9pzhj 1373 19 the the DT cord-005646-xhx9pzhj 1373 20 observed observed JJ cord-005646-xhx9pzhj 1373 21 vasoconstriction vasoconstriction NN cord-005646-xhx9pzhj 1373 22 , , , cord-005646-xhx9pzhj 1373 23 bronchoconstriction bronchoconstriction NN cord-005646-xhx9pzhj 1373 24 and and CC cord-005646-xhx9pzhj 1373 25 smooth smooth JJ cord-005646-xhx9pzhj 1373 26 muscle muscle NN cord-005646-xhx9pzhj 1373 27 hypertrophy hypertrophy NN cord-005646-xhx9pzhj 1373 28 . . . cord-005646-xhx9pzhj 1374 1 Prince Prince NNP cord-005646-xhx9pzhj 1374 2 of of IN cord-005646-xhx9pzhj 1374 3 Wales Wales NNP cord-005646-xhx9pzhj 1374 4 Children Children NNP cord-005646-xhx9pzhj 1374 5 's 's POS cord-005646-xhx9pzhj 1374 6 Hospital Hospital NNP cord-005646-xhx9pzhj 1374 7 University University NNP cord-005646-xhx9pzhj 1374 8 of of IN cord-005646-xhx9pzhj 1374 9 New New NNP cord-005646-xhx9pzhj 1374 10 South South NNP cord-005646-xhx9pzhj 1374 11 Wales Wales NNP cord-005646-xhx9pzhj 1374 12 , , , cord-005646-xhx9pzhj 1374 13 Randwick Randwick NNP cord-005646-xhx9pzhj 1374 14 , , , cord-005646-xhx9pzhj 1374 15 N.S.W. N.S.W. NNP cord-005646-xhx9pzhj 1374 16 Australia Australia NNP cord-005646-xhx9pzhj 1374 17 . . . cord-005646-xhx9pzhj 1375 1 INTRODUCTION INTRODUCTION NNP cord-005646-xhx9pzhj 1376 1 An an DT cord-005646-xhx9pzhj 1376 2 increasing increase VBG cord-005646-xhx9pzhj 1376 3 mortality mortality NN cord-005646-xhx9pzhj 1376 4 in in IN cord-005646-xhx9pzhj 1376 5 asthmatic asthmatic JJ cord-005646-xhx9pzhj 1376 6 children child NNS cord-005646-xhx9pzhj 1376 7 has have VBZ cord-005646-xhx9pzhj 1376 8 been be VBN cord-005646-xhx9pzhj 1376 9 reported report VBN cord-005646-xhx9pzhj 1376 10 . . . cord-005646-xhx9pzhj 1377 1 The the DT cord-005646-xhx9pzhj 1377 2 increased increase VBN cord-005646-xhx9pzhj 1377 3 severity severity NN cord-005646-xhx9pzhj 1377 4 of of IN cord-005646-xhx9pzhj 1377 5 asthmatic asthmatic JJ cord-005646-xhx9pzhj 1377 6 illness illness NN cord-005646-xhx9pzhj 1377 7 leads lead VBZ cord-005646-xhx9pzhj 1377 8 to to IN cord-005646-xhx9pzhj 1377 9 an an DT cord-005646-xhx9pzhj 1377 10 increased increase VBN cord-005646-xhx9pzhj 1377 11 demand demand NN cord-005646-xhx9pzhj 1377 12 for for IN cord-005646-xhx9pzhj 1377 13 ICU ICU NNP cord-005646-xhx9pzhj 1377 14 admission admission NN cord-005646-xhx9pzhj 1377 15 , , , cord-005646-xhx9pzhj 1377 16 and and CC cord-005646-xhx9pzhj 1377 17 a a DT cord-005646-xhx9pzhj 1377 18 corresponding corresponding JJ cord-005646-xhx9pzhj 1377 19 increased increase VBN cord-005646-xhx9pzhj 1377 20 need need NN cord-005646-xhx9pzhj 1377 21 for for IN cord-005646-xhx9pzhj 1377 22 mechanical mechanical JJ cord-005646-xhx9pzhj 1377 23 ventilation ventilation NN cord-005646-xhx9pzhj 1377 24 . . . cord-005646-xhx9pzhj 1378 1 Geographic geographic JJ cord-005646-xhx9pzhj 1378 2 end end VBP cord-005646-xhx9pzhj 1378 3 environmental environmental JJ cord-005646-xhx9pzhj 1378 4 factors factor NNS cord-005646-xhx9pzhj 1378 5 are be VBP cord-005646-xhx9pzhj 1378 6 thought think VBN cord-005646-xhx9pzhj 1378 7 to to TO cord-005646-xhx9pzhj 1378 8 be be VB cord-005646-xhx9pzhj 1378 9 partly partly RB cord-005646-xhx9pzhj 1378 10 responsible responsible JJ cord-005646-xhx9pzhj 1378 11 for for IN cord-005646-xhx9pzhj 1378 12 differences difference NNS cord-005646-xhx9pzhj 1378 13 in in IN cord-005646-xhx9pzhj 1378 14 disease disease NN cord-005646-xhx9pzhj 1378 15 sevedty sevedty NNP cord-005646-xhx9pzhj 1378 16 throughout throughout IN cord-005646-xhx9pzhj 1378 17 the the DT cord-005646-xhx9pzhj 1378 18 wodd wodd NNP cord-005646-xhx9pzhj 1378 19 . . . cord-005646-xhx9pzhj 1379 1 For for IN cord-005646-xhx9pzhj 1379 2 this this DT cord-005646-xhx9pzhj 1379 3 reason reason NN cord-005646-xhx9pzhj 1379 4 , , , cord-005646-xhx9pzhj 1379 5 epidemiological epidemiological JJ cord-005646-xhx9pzhj 1379 6 studies study NNS cord-005646-xhx9pzhj 1379 7 from from IN cord-005646-xhx9pzhj 1379 8 diverse diverse JJ cord-005646-xhx9pzhj 1379 9 areas area NNS cord-005646-xhx9pzhj 1379 10 are be VBP cord-005646-xhx9pzhj 1379 11 important important JJ cord-005646-xhx9pzhj 1379 12 , , , cord-005646-xhx9pzhj 1379 13 Risk risk NN cord-005646-xhx9pzhj 1379 14 factors factor NNS cord-005646-xhx9pzhj 1379 15 for for IN cord-005646-xhx9pzhj 1379 16 ICU ICU NNP cord-005646-xhx9pzhj 1379 17 admission admission NN cord-005646-xhx9pzhj 1379 18 , , , cord-005646-xhx9pzhj 1379 19 and and CC cord-005646-xhx9pzhj 1379 20 for for IN cord-005646-xhx9pzhj 1379 21 the the DT cord-005646-xhx9pzhj 1379 22 institution institution NN cord-005646-xhx9pzhj 1379 23 of of IN cord-005646-xhx9pzhj 1379 24 mechanical mechanical JJ cord-005646-xhx9pzhj 1379 25 ventilation ventilation NN cord-005646-xhx9pzhj 1379 26 should should MD cord-005646-xhx9pzhj 1379 27 be be VB cord-005646-xhx9pzhj 1379 28 identified identify VBN cord-005646-xhx9pzhj 1379 29 , , , cord-005646-xhx9pzhj 1379 30 to to TO cord-005646-xhx9pzhj 1379 31 optimise optimise VB cord-005646-xhx9pzhj 1379 32 ICU ICU NNP cord-005646-xhx9pzhj 1379 33 admission admission NN cord-005646-xhx9pzhj 1379 34 criteria criterion NNS cord-005646-xhx9pzhj 1379 35 and and CC cord-005646-xhx9pzhj 1379 36 to to TO cord-005646-xhx9pzhj 1379 37 avoid avoid VB cord-005646-xhx9pzhj 1379 38 unnecessary unnecessary JJ cord-005646-xhx9pzhj 1379 39 delays delay NNS cord-005646-xhx9pzhj 1379 40 in in IN cord-005646-xhx9pzhj 1379 41 admitting admit VBG cord-005646-xhx9pzhj 1379 42 at at IN cord-005646-xhx9pzhj 1379 43 - - HYPH cord-005646-xhx9pzhj 1379 44 risk risk NN cord-005646-xhx9pzhj 1379 45 patients patient NNS cord-005646-xhx9pzhj 1379 46 . . . cord-005646-xhx9pzhj 1380 1 AIM aim VB cord-005646-xhx9pzhj 1380 2 To to TO cord-005646-xhx9pzhj 1380 3 document document VB cord-005646-xhx9pzhj 1380 4 the the DT cord-005646-xhx9pzhj 1380 5 clinical clinical JJ cord-005646-xhx9pzhj 1380 6 characteristics characteristic NNS cord-005646-xhx9pzhj 1380 7 of of IN cord-005646-xhx9pzhj 1380 8 ventilated ventilate VBN cord-005646-xhx9pzhj 1380 9 and and CC cord-005646-xhx9pzhj 1380 10 non non JJ cord-005646-xhx9pzhj 1380 11 - - JJ cord-005646-xhx9pzhj 1380 12 ventilated ventilated JJ cord-005646-xhx9pzhj 1380 13 asthmatic asthmatic JJ cord-005646-xhx9pzhj 1380 14 patients patient NNS cord-005646-xhx9pzhj 1380 15 admitted admit VBN cord-005646-xhx9pzhj 1380 16 to to IN cord-005646-xhx9pzhj 1380 17 ICU ICU NNP cord-005646-xhx9pzhj 1380 18 . . . cord-005646-xhx9pzhj 1381 1 METHODS methods NN cord-005646-xhx9pzhj 1382 1 This this DT cord-005646-xhx9pzhj 1382 2 is be VBZ cord-005646-xhx9pzhj 1382 3 a a DT cord-005646-xhx9pzhj 1382 4 retrospective retrospective JJ cord-005646-xhx9pzhj 1382 5 study study NN cord-005646-xhx9pzhj 1382 6 of of IN cord-005646-xhx9pzhj 1382 7 all all DT cord-005646-xhx9pzhj 1382 8 paediatric paediatric JJ cord-005646-xhx9pzhj 1382 9 asthma asthma NN cord-005646-xhx9pzhj 1382 10 ICU ICU NNP cord-005646-xhx9pzhj 1382 11 admissions admission NNS cord-005646-xhx9pzhj 1382 12 from from IN cord-005646-xhx9pzhj 1382 13 January January NNP cord-005646-xhx9pzhj 1382 14 1990 1990 CD cord-005646-xhx9pzhj 1382 15 to to IN cord-005646-xhx9pzhj 1382 16 December December NNP cord-005646-xhx9pzhj 1382 17 1995 1995 CD cord-005646-xhx9pzhj 1382 18 . . . cord-005646-xhx9pzhj 1383 1 RESULTS result NNS cord-005646-xhx9pzhj 1384 1 There there EX cord-005646-xhx9pzhj 1384 2 were be VBD cord-005646-xhx9pzhj 1384 3 65 65 CD cord-005646-xhx9pzhj 1384 4 patients patient NNS cord-005646-xhx9pzhj 1384 5 admitted admit VBN cord-005646-xhx9pzhj 1384 6 to to IN cord-005646-xhx9pzhj 1384 7 the the DT cord-005646-xhx9pzhj 1384 8 ICU ICU NNP cord-005646-xhx9pzhj 1384 9 for for IN cord-005646-xhx9pzhj 1384 10 acute acute JJ cord-005646-xhx9pzhj 1384 11 severe severe JJ cord-005646-xhx9pzhj 1384 12 asthma asthma NN cord-005646-xhx9pzhj 1384 13 in in IN cord-005646-xhx9pzhj 1384 14 the the DT cord-005646-xhx9pzhj 1384 15 study study NN cord-005646-xhx9pzhj 1384 16 period period NN cord-005646-xhx9pzhj 1384 17 . . . cord-005646-xhx9pzhj 1385 1 The the DT cord-005646-xhx9pzhj 1385 2 male male JJ cord-005646-xhx9pzhj 1385 3 : : : cord-005646-xhx9pzhj 1385 4 female female JJ cord-005646-xhx9pzhj 1385 5 ratio ratio NN cord-005646-xhx9pzhj 1385 6 was be VBD cord-005646-xhx9pzhj 1385 7 33:32 33:32 CD cord-005646-xhx9pzhj 1385 8 , , , cord-005646-xhx9pzhj 1386 1 the the DT cord-005646-xhx9pzhj 1386 2 mean mean JJ cord-005646-xhx9pzhj 1386 3 age age NN cord-005646-xhx9pzhj 1386 4 76.1 76.1 CD cord-005646-xhx9pzhj 1386 5 • • XX cord-005646-xhx9pzhj 1387 1 57.3 57.3 CD cord-005646-xhx9pzhj 1387 2 months month NNS cord-005646-xhx9pzhj 1387 3 , , , cord-005646-xhx9pzhj 1387 4 the the DT cord-005646-xhx9pzhj 1387 5 mean mean JJ cord-005646-xhx9pzhj 1387 6 PRISM PRISM NNP cord-005646-xhx9pzhj 1387 7 8.5 8.5 CD cord-005646-xhx9pzhj 1387 8 4 4 CD cord-005646-xhx9pzhj 1387 9 - - SYM cord-005646-xhx9pzhj 1387 10 11.1 11.1 CD cord-005646-xhx9pzhj 1387 11 % % NN cord-005646-xhx9pzhj 1387 12 , , , cord-005646-xhx9pzhj 1387 13 and and CC cord-005646-xhx9pzhj 1387 14 the the DT cord-005646-xhx9pzhj 1387 15 mean mean JJ cord-005646-xhx9pzhj 1387 16 duration duration NN cord-005646-xhx9pzhj 1387 17 of of IN cord-005646-xhx9pzhj 1387 18 admission admission NN cord-005646-xhx9pzhj 1387 19 135 135 CD cord-005646-xhx9pzhj 1387 20 4 4 CD cord-005646-xhx9pzhj 1387 21 . . . cord-005646-xhx9pzhj 1388 1 129 129 CD cord-005646-xhx9pzhj 1388 2 hours hour NNS cord-005646-xhx9pzhj 1388 3 . . . cord-005646-xhx9pzhj 1389 1 There there EX cord-005646-xhx9pzhj 1389 2 was be VBD cord-005646-xhx9pzhj 1389 3 no no DT cord-005646-xhx9pzhj 1389 4 seasonal seasonal JJ cord-005646-xhx9pzhj 1389 5 variation variation NN cord-005646-xhx9pzhj 1389 6 in in IN cord-005646-xhx9pzhj 1389 7 admissions admission NNS cord-005646-xhx9pzhj 1389 8 . . . cord-005646-xhx9pzhj 1390 1 Only only RB cord-005646-xhx9pzhj 1390 2 40 40 CD cord-005646-xhx9pzhj 1390 3 % % NN cord-005646-xhx9pzhj 1390 4 ( ( -LRB- cord-005646-xhx9pzhj 1390 5 26/65 26/65 CD cord-005646-xhx9pzhj 1390 6 ) ) -RRB- cord-005646-xhx9pzhj 1391 1 patients patient NNS cord-005646-xhx9pzhj 1391 2 required require VBD cord-005646-xhx9pzhj 1391 3 mechanical mechanical JJ cord-005646-xhx9pzhj 1391 4 ventilation ventilation NN cord-005646-xhx9pzhj 1391 5 . . . cord-005646-xhx9pzhj 1392 1 In in IN cord-005646-xhx9pzhj 1392 2 22 22 CD cord-005646-xhx9pzhj 1392 3 % % NN cord-005646-xhx9pzhj 1392 4 of of IN cord-005646-xhx9pzhj 1392 5 all all DT cord-005646-xhx9pzhj 1392 6 patients patient NNS cord-005646-xhx9pzhj 1392 7 this this DT cord-005646-xhx9pzhj 1392 8 was be VBD cord-005646-xhx9pzhj 1392 9 the the DT cord-005646-xhx9pzhj 1392 10 first first JJ cord-005646-xhx9pzhj 1392 11 presentation presentation NN cord-005646-xhx9pzhj 1392 12 with with IN cord-005646-xhx9pzhj 1392 13 asthma asthma NN cord-005646-xhx9pzhj 1392 14 . . . cord-005646-xhx9pzhj 1393 1 There there EX cord-005646-xhx9pzhj 1393 2 were be VBD cord-005646-xhx9pzhj 1393 3 some some DT cord-005646-xhx9pzhj 1393 4 significant significant JJ cord-005646-xhx9pzhj 1393 5 differences difference NNS cord-005646-xhx9pzhj 1393 6 between between IN cord-005646-xhx9pzhj 1393 7 ventilated ventilated JJ cord-005646-xhx9pzhj 1393 8 and and CC cord-005646-xhx9pzhj 1393 9 non non JJ cord-005646-xhx9pzhj 1393 10 - - JJ cord-005646-xhx9pzhj 1393 11 ventilated ventilated JJ cord-005646-xhx9pzhj 1393 12 patients patient NNS cord-005646-xhx9pzhj 1393 13 ( ( -LRB- cord-005646-xhx9pzhj 1393 14 see see VB cord-005646-xhx9pzhj 1393 15 Table table NN cord-005646-xhx9pzhj 1393 16 ) ) -RRB- cord-005646-xhx9pzhj 1393 17 . . . cord-005646-xhx9pzhj 1394 1 There there EX cord-005646-xhx9pzhj 1394 2 was be VBD cord-005646-xhx9pzhj 1394 3 a a DT cord-005646-xhx9pzhj 1394 4 significantly significantly RB cord-005646-xhx9pzhj 1394 5 higher high JJR cord-005646-xhx9pzhj 1394 6 incidence incidence NN cord-005646-xhx9pzhj 1394 7 of of IN cord-005646-xhx9pzhj 1394 8 concomitant concomitant JJ cord-005646-xhx9pzhj 1394 9 and and CC cord-005646-xhx9pzhj 1394 10 nosocomial nosocomial JJ cord-005646-xhx9pzhj 1394 11 pneumonias pneumonia NNS cord-005646-xhx9pzhj 1394 12 in in IN cord-005646-xhx9pzhj 1394 13 the the DT cord-005646-xhx9pzhj 1394 14 ventilated ventilate VBN cord-005646-xhx9pzhj 1394 15 patients patient NNS cord-005646-xhx9pzhj 1394 16 ( ( -LRB- cord-005646-xhx9pzhj 1394 17 84.0 84.0 CD cord-005646-xhx9pzhj 1394 18 % % NN cord-005646-xhx9pzhj 1394 19 vs vs IN cord-005646-xhx9pzhj 1394 20 21.1 21.1 CD cord-005646-xhx9pzhj 1394 21 % % NN cord-005646-xhx9pzhj 1394 22 ) ) -RRB- cord-005646-xhx9pzhj 1394 23 as as RB cord-005646-xhx9pzhj 1394 24 well well RB cord-005646-xhx9pzhj 1394 25 as as IN cord-005646-xhx9pzhj 1394 26 segmental segmental JJ cord-005646-xhx9pzhj 1394 27 lung lung NN cord-005646-xhx9pzhj 1394 28 collapse collapse NN cord-005646-xhx9pzhj 1394 29 ( ( -LRB- cord-005646-xhx9pzhj 1394 30 68.0 68.0 CD cord-005646-xhx9pzhj 1394 31 % % NN cord-005646-xhx9pzhj 1394 32 vs vs IN cord-005646-xhx9pzhj 1394 33 26.3 26.3 CD cord-005646-xhx9pzhj 1394 34 % % NN cord-005646-xhx9pzhj 1394 35 ) ) -RRB- cord-005646-xhx9pzhj 1394 36 . . . cord-005646-xhx9pzhj 1395 1 There there EX cord-005646-xhx9pzhj 1395 2 were be VBD cord-005646-xhx9pzhj 1395 3 no no DT cord-005646-xhx9pzhj 1395 4 deaths death NNS cord-005646-xhx9pzhj 1395 5 . . . cord-005646-xhx9pzhj 1396 1 DISCUSSION discussion NN cord-005646-xhx9pzhj 1397 1 The the DT cord-005646-xhx9pzhj 1397 2 need need NN cord-005646-xhx9pzhj 1397 3 of of IN cord-005646-xhx9pzhj 1397 4 mechanical mechanical JJ cord-005646-xhx9pzhj 1397 5 ventilation ventilation NN cord-005646-xhx9pzhj 1397 6 significantly significantly RB cord-005646-xhx9pzhj 1397 7 increases increase VBZ cord-005646-xhx9pzhj 1397 8 the the DT cord-005646-xhx9pzhj 1397 9 morbidity morbidity NN cord-005646-xhx9pzhj 1397 10 of of IN cord-005646-xhx9pzhj 1397 11 and and CC cord-005646-xhx9pzhj 1397 12 duration duration NN cord-005646-xhx9pzhj 1397 13 of of IN cord-005646-xhx9pzhj 1397 14 ICU ICU NNP cord-005646-xhx9pzhj 1397 15 stay stay NN cord-005646-xhx9pzhj 1397 16 of of IN cord-005646-xhx9pzhj 1397 17 asthmatic asthmatic JJ cord-005646-xhx9pzhj 1397 18 patients patient NNS cord-005646-xhx9pzhj 1397 19 . . . cord-005646-xhx9pzhj 1398 1 Younger young JJR cord-005646-xhx9pzhj 1398 2 asthmatic asthmatic JJ cord-005646-xhx9pzhj 1398 3 paediatdc paediatdc NN cord-005646-xhx9pzhj 1398 4 patients patient NNS cord-005646-xhx9pzhj 1398 5 have have VBP cord-005646-xhx9pzhj 1398 6 a a DT cord-005646-xhx9pzhj 1398 7 significantly significantly RB cord-005646-xhx9pzhj 1398 8 higher high JJR cord-005646-xhx9pzhj 1398 9 risk risk NN cord-005646-xhx9pzhj 1398 10 of of IN cord-005646-xhx9pzhj 1398 11 ventilation ventilation NN cord-005646-xhx9pzhj 1398 12 . . . cord-005646-xhx9pzhj 1399 1 The the DT cord-005646-xhx9pzhj 1399 2 need need NN cord-005646-xhx9pzhj 1399 3 for for IN cord-005646-xhx9pzhj 1399 4 ventilation ventilation NN cord-005646-xhx9pzhj 1399 5 is be VBZ cord-005646-xhx9pzhj 1399 6 predicted predict VBN cord-005646-xhx9pzhj 1399 7 principally principally RB cord-005646-xhx9pzhj 1399 8 from from IN cord-005646-xhx9pzhj 1399 9 a a DT cord-005646-xhx9pzhj 1399 10 worsening worsen VBG cord-005646-xhx9pzhj 1399 11 pCO2 pCO2 NNP cord-005646-xhx9pzhj 1399 12 and and CC cord-005646-xhx9pzhj 1399 13 respiratory respiratory JJ cord-005646-xhx9pzhj 1399 14 acidaemia acidaemia NN cord-005646-xhx9pzhj 1399 15 , , , cord-005646-xhx9pzhj 1399 16 which which WDT cord-005646-xhx9pzhj 1399 17 is be VBZ cord-005646-xhx9pzhj 1399 18 often often RB cord-005646-xhx9pzhj 1399 19 independently independently RB cord-005646-xhx9pzhj 1399 20 interpreted interpret VBN cord-005646-xhx9pzhj 1399 21 by by IN cord-005646-xhx9pzhj 1399 22 the the DT cord-005646-xhx9pzhj 1399 23 clinician clinician NN cord-005646-xhx9pzhj 1399 24 as as IN cord-005646-xhx9pzhj 1399 25 respira4ory respira4ory JJ cord-005646-xhx9pzhj 1399 26 exhaustion exhaustion NN cord-005646-xhx9pzhj 1399 27 . . . cord-005646-xhx9pzhj 1400 1 This this DT cord-005646-xhx9pzhj 1400 2 study study NN cord-005646-xhx9pzhj 1400 3 has have VBZ cord-005646-xhx9pzhj 1400 4 shown show VBN cord-005646-xhx9pzhj 1400 5 that that IN cord-005646-xhx9pzhj 1400 6 ICU ICU NNP cord-005646-xhx9pzhj 1400 7 admission admission NN cord-005646-xhx9pzhj 1400 8 is be VBZ cord-005646-xhx9pzhj 1400 9 important important JJ cord-005646-xhx9pzhj 1400 10 in in IN cord-005646-xhx9pzhj 1400 11 the the DT cord-005646-xhx9pzhj 1400 12 management management NN cord-005646-xhx9pzhj 1400 13 of of IN cord-005646-xhx9pzhj 1400 14 young young JJ cord-005646-xhx9pzhj 1400 15 paediatdc paediatdc NN cord-005646-xhx9pzhj 1400 16 patients patient NNS cord-005646-xhx9pzhj 1400 17 with with IN cord-005646-xhx9pzhj 1400 18 acute acute JJ cord-005646-xhx9pzhj 1400 19 severe severe JJ cord-005646-xhx9pzhj 1400 20 asthma asthma NN cord-005646-xhx9pzhj 1400 21 and and CC cord-005646-xhx9pzhj 1400 22 respiratgry respiratgry NNP cord-005646-xhx9pzhj 1400 23 fa!!ure fa!!ure NNP cord-005646-xhx9pzhj 1400 24 . . . cord-005646-xhx9pzhj 1400 25 _SP cord-005646-xhx9pzhj 1401 1 Intravenous intravenous NN cord-005646-xhx9pzhj 1401 2 salbutamoi salbutamoi NNS cord-005646-xhx9pzhj 1401 3 in in IN cord-005646-xhx9pzhj 1401 4 the the DT cord-005646-xhx9pzhj 1401 5 emergency emergency NN cord-005646-xhx9pzhj 1401 6 , , , cord-005646-xhx9pzhj 1401 7 department department NN cord-005646-xhx9pzhj 1401 8 management management NN cord-005646-xhx9pzhj 1401 9 of of IN cord-005646-xhx9pzhj 1401 10 severe severe JJ cord-005646-xhx9pzhj 1401 11 asthma asthma NN cord-005646-xhx9pzhj 1401 12 in in IN cord-005646-xhx9pzhj 1401 13 children child NNS cord-005646-xhx9pzhj 1401 14 . . . cord-005646-xhx9pzhj 1402 1 G.J.Browne G.J.Browne NNP cord-005646-xhx9pzhj 1402 2 , , , cord-005646-xhx9pzhj 1402 3 A. A. NNP cord-005646-xhx9pzhj 1402 4 Perma Perma NNP cord-005646-xhx9pzhj 1402 5 , , , cord-005646-xhx9pzhj 1402 6 X. X. NNP cord-005646-xhx9pzhj 1402 7 Phung Phung NNP cord-005646-xhx9pzhj 1402 8 , , , cord-005646-xhx9pzhj 1402 9 M.Soo M.Soo NNP cord-005646-xhx9pzhj 1402 10 Westmead Westmead NNP cord-005646-xhx9pzhj 1402 11 Hospital Hospital NNP cord-005646-xhx9pzhj 1402 12 , , , cord-005646-xhx9pzhj 1402 13 Sydney Sydney NNP cord-005646-xhx9pzhj 1402 14 , , , cord-005646-xhx9pzhj 1402 15 Australia Australia NNP cord-005646-xhx9pzhj 1402 16 . . . cord-005646-xhx9pzhj 1403 1 It -PRON- PRP cord-005646-xhx9pzhj 1403 2 is be VBZ cord-005646-xhx9pzhj 1403 3 postulate postulate JJ cord-005646-xhx9pzhj 1403 4 that that IN cord-005646-xhx9pzhj 1403 5 if if IN cord-005646-xhx9pzhj 1403 6 an an DT cord-005646-xhx9pzhj 1403 7 initial initial JJ cord-005646-xhx9pzhj 1403 8 intravenous intravenous JJ cord-005646-xhx9pzhj 1403 9 loading loading NN cord-005646-xhx9pzhj 1403 10 dose dose NN cord-005646-xhx9pzhj 1403 11 of of IN cord-005646-xhx9pzhj 1403 12 salbutamol salbutamol NN cord-005646-xhx9pzhj 1403 13 is be VBZ cord-005646-xhx9pzhj 1403 14 given give VBN cord-005646-xhx9pzhj 1403 15 in in IN cord-005646-xhx9pzhj 1403 16 severe severe JJ cord-005646-xhx9pzhj 1403 17 asthma asthma NN cord-005646-xhx9pzhj 1403 18 , , , cord-005646-xhx9pzhj 1403 19 a a DT cord-005646-xhx9pzhj 1403 20 more more RBR cord-005646-xhx9pzhj 1403 21 rapid rapid JJ cord-005646-xhx9pzhj 1403 22 clinical clinical JJ cord-005646-xhx9pzhj 1403 23 response response NN cord-005646-xhx9pzhj 1403 24 will will MD cord-005646-xhx9pzhj 1403 25 occur occur VB cord-005646-xhx9pzhj 1403 26 , , , cord-005646-xhx9pzhj 1403 27 reducing reduce VBG cord-005646-xhx9pzhj 1403 28 requirements requirement NNS cord-005646-xhx9pzhj 1403 29 for for IN cord-005646-xhx9pzhj 1403 30 continued continued JJ cord-005646-xhx9pzhj 1403 31 high high JJ cord-005646-xhx9pzhj 1403 32 doses dose NNS cord-005646-xhx9pzhj 1403 33 of of IN cord-005646-xhx9pzhj 1403 34 nebulised nebulised NNP cord-005646-xhx9pzhj 1403 35 salbutamoi salbutamoi NNS cord-005646-xhx9pzhj 1403 36 with with IN cord-005646-xhx9pzhj 1403 37 fewer few JJR cord-005646-xhx9pzhj 1403 38 side side NN cord-005646-xhx9pzhj 1403 39 effects effect NNS cord-005646-xhx9pzhj 1403 40 . . . cord-005646-xhx9pzhj 1404 1 This this DT cord-005646-xhx9pzhj 1404 2 double double JJ cord-005646-xhx9pzhj 1404 3 blinded blinded JJ cord-005646-xhx9pzhj 1404 4 study study NN cord-005646-xhx9pzhj 1404 5 was be VBD cord-005646-xhx9pzhj 1404 6 conducted conduct VBN cord-005646-xhx9pzhj 1404 7 in in IN cord-005646-xhx9pzhj 1404 8 the the DT cord-005646-xhx9pzhj 1404 9 Emergency Emergency NNP cord-005646-xhx9pzhj 1404 10 department department NN cord-005646-xhx9pzhj 1404 11 of of IN cord-005646-xhx9pzhj 1404 12 Westmead Westmead NNP cord-005646-xhx9pzhj 1404 13 Hospital Hospital NNP cord-005646-xhx9pzhj 1404 14 a a DT cord-005646-xhx9pzhj 1404 15 university university NN cord-005646-xhx9pzhj 1404 16 hospital hospital NN cord-005646-xhx9pzhj 1404 17 in in IN cord-005646-xhx9pzhj 1404 18 Sydney Sydney NNP cord-005646-xhx9pzhj 1404 19 , , , cord-005646-xhx9pzhj 1404 20 Australia Australia NNP cord-005646-xhx9pzhj 1404 21 . . . cord-005646-xhx9pzhj 1405 1 All all DT cord-005646-xhx9pzhj 1405 2 children child NNS cord-005646-xhx9pzhj 1405 3 with with IN cord-005646-xhx9pzhj 1405 4 severe severe JJ cord-005646-xhx9pzhj 1405 5 asthma asthma NN cord-005646-xhx9pzhj 1405 6 had have VBD cord-005646-xhx9pzhj 1405 7 initial initial JJ cord-005646-xhx9pzhj 1405 8 nebuliser nebuliser NN cord-005646-xhx9pzhj 1405 9 therapy therapy NN cord-005646-xhx9pzhj 1405 10 ( ( -LRB- cord-005646-xhx9pzhj 1405 11 5rag 5rag CD cord-005646-xhx9pzhj 1405 12 of of IN cord-005646-xhx9pzhj 1405 13 salbutamol salbutamol NN cord-005646-xhx9pzhj 1405 14 with with IN cord-005646-xhx9pzhj 1405 15 4mL 4ml CD cord-005646-xhx9pzhj 1405 16 of of IN cord-005646-xhx9pzhj 1405 17 saline saline NN cord-005646-xhx9pzhj 1405 18 ) ) -RRB- cord-005646-xhx9pzhj 1405 19 . . . cord-005646-xhx9pzhj 1406 1 If if IN cord-005646-xhx9pzhj 1406 2 asthma asthma NN cord-005646-xhx9pzhj 1406 3 remained remain VBD cord-005646-xhx9pzhj 1406 4 severe severe JJ cord-005646-xhx9pzhj 1406 5 20 20 CD cord-005646-xhx9pzhj 1406 6 minutes minute NNS cord-005646-xhx9pzhj 1406 7 later later RB cord-005646-xhx9pzhj 1406 8 , , , cord-005646-xhx9pzhj 1406 9 they -PRON- PRP cord-005646-xhx9pzhj 1406 10 were be VBD cord-005646-xhx9pzhj 1406 11 given give VBN cord-005646-xhx9pzhj 1406 12 a a DT cord-005646-xhx9pzhj 1406 13 dose dose NN cord-005646-xhx9pzhj 1406 14 of of IN cord-005646-xhx9pzhj 1406 15 intravenous intravenous JJ cord-005646-xhx9pzhj 1406 16 hydrocortisone hydrocortisone NN cord-005646-xhx9pzhj 1406 17 ( ( -LRB- cord-005646-xhx9pzhj 1406 18 5mg 5mg NNP cord-005646-xhx9pzhj 1406 19 / / SYM cord-005646-xhx9pzhj 1406 20 kg kg NNP cord-005646-xhx9pzhj 1406 21 ) ) -RRB- cord-005646-xhx9pzhj 1406 22 and and CC cord-005646-xhx9pzhj 1406 23 either either CC cord-005646-xhx9pzhj 1406 24 normal normal JJ cord-005646-xhx9pzhj 1406 25 saline saline NN cord-005646-xhx9pzhj 1406 26 or or CC cord-005646-xhx9pzhj 1406 27 salbutamol salbutamol NN cord-005646-xhx9pzhj 1407 1 15microgm 15microgm LS cord-005646-xhx9pzhj 1407 2 / / SYM cord-005646-xhx9pzhj 1407 3 kg kg NNS cord-005646-xhx9pzhj 1407 4 intravenously intravenously RB cord-005646-xhx9pzhj 1407 5 . . . cord-005646-xhx9pzhj 1408 1 Frequent frequent JJ cord-005646-xhx9pzhj 1408 2 nebulised nebulised JJ cord-005646-xhx9pzhj 1408 3 salbutamoi salbutamoi NNP cord-005646-xhx9pzhj 1408 4 therapy therapy NNP cord-005646-xhx9pzhj 1408 5 continued continue VBD cord-005646-xhx9pzhj 1408 6 during during IN cord-005646-xhx9pzhj 1408 7 the the DT cord-005646-xhx9pzhj 1408 8 initial initial JJ cord-005646-xhx9pzhj 1408 9 first first JJ cord-005646-xhx9pzhj 1408 10 hour hour NN cord-005646-xhx9pzhj 1408 11 if if IN cord-005646-xhx9pzhj 1408 12 clinically clinically RB cord-005646-xhx9pzhj 1408 13 indicated indicate VBN cord-005646-xhx9pzhj 1408 14 . . . cord-005646-xhx9pzhj 1409 1 Continuous continuous JJ cord-005646-xhx9pzhj 1409 2 respiratory respiratory NN cord-005646-xhx9pzhj 1409 3 and and CC cord-005646-xhx9pzhj 1409 4 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 1409 5 monitoring monitoring NN cord-005646-xhx9pzhj 1409 6 occurred occur VBD cord-005646-xhx9pzhj 1409 7 in in IN cord-005646-xhx9pzhj 1409 8 the the DT cord-005646-xhx9pzhj 1409 9 first first JJ cord-005646-xhx9pzhj 1409 10 2 2 CD cord-005646-xhx9pzhj 1409 11 hours hour NNS cord-005646-xhx9pzhj 1409 12 . . . cord-005646-xhx9pzhj 1410 1 Serum serum NN cord-005646-xhx9pzhj 1410 2 potassium potassium NN cord-005646-xhx9pzhj 1410 3 and and CC cord-005646-xhx9pzhj 1410 4 glucose glucose NN cord-005646-xhx9pzhj 1410 5 determinations determination NNS cord-005646-xhx9pzhj 1410 6 were be VBD cord-005646-xhx9pzhj 1410 7 made make VBN cord-005646-xhx9pzhj 1410 8 at at IN cord-005646-xhx9pzhj 1410 9 study study NN cord-005646-xhx9pzhj 1410 10 commencement commencement NN cord-005646-xhx9pzhj 1410 11 and and CC cord-005646-xhx9pzhj 1410 12 1 1 CD cord-005646-xhx9pzhj 1410 13 hour hour NN cord-005646-xhx9pzhj 1410 14 after after IN cord-005646-xhx9pzhj 1410 15 intravenous intravenous JJ cord-005646-xhx9pzhj 1410 16 therapy therapy NN cord-005646-xhx9pzhj 1410 17 . . . cord-005646-xhx9pzhj 1411 1 Salbutamol salbutamol JJ cord-005646-xhx9pzhj 1411 2 determination determination NN cord-005646-xhx9pzhj 1411 3 was be VBD cord-005646-xhx9pzhj 1411 4 made make VBN cord-005646-xhx9pzhj 1411 5 at at IN cord-005646-xhx9pzhj 1411 6 study study NN cord-005646-xhx9pzhj 1411 7 commencement commencement NN cord-005646-xhx9pzhj 1411 8 . . . cord-005646-xhx9pzhj 1412 1 Children child NNS cord-005646-xhx9pzhj 1412 2 remained remain VBD cord-005646-xhx9pzhj 1412 3 clinically clinically RB cord-005646-xhx9pzhj 1412 4 monitored monitor VBN cord-005646-xhx9pzhj 1412 5 for for IN cord-005646-xhx9pzhj 1412 6 the the DT cord-005646-xhx9pzhj 1412 7 next next JJ cord-005646-xhx9pzhj 1412 8 22 22 CD cord-005646-xhx9pzhj 1412 9 hours hour NNS cord-005646-xhx9pzhj 1412 10 , , , cord-005646-xhx9pzhj 1412 11 with with IN cord-005646-xhx9pzhj 1412 12 their -PRON- PRP$ cord-005646-xhx9pzhj 1412 13 ongoing ongoing JJ cord-005646-xhx9pzhj 1412 14 treatment treatment NN cord-005646-xhx9pzhj 1412 15 determined determine VBN cord-005646-xhx9pzhj 1412 16 by by IN cord-005646-xhx9pzhj 1412 17 clinical clinical JJ cord-005646-xhx9pzhj 1412 18 response response NN cord-005646-xhx9pzhj 1412 19 . . . cord-005646-xhx9pzhj 1413 1 29 29 CD cord-005646-xhx9pzhj 1413 2 children child NNS cord-005646-xhx9pzhj 1413 3 with with IN cord-005646-xhx9pzhj 1413 4 severe severe JJ cord-005646-xhx9pzhj 1413 5 asthma asthma NN cord-005646-xhx9pzhj 1413 6 12 12 CD cord-005646-xhx9pzhj 1413 7 months month NNS cord-005646-xhx9pzhj 1413 8 to to IN cord-005646-xhx9pzhj 1413 9 12 12 CD cord-005646-xhx9pzhj 1413 10 years year NNS cord-005646-xhx9pzhj 1413 11 of of IN cord-005646-xhx9pzhj 1413 12 age age NN cord-005646-xhx9pzhj 1413 13 were be VBD cord-005646-xhx9pzhj 1413 14 studied study VBN cord-005646-xhx9pzhj 1413 15 , , , cord-005646-xhx9pzhj 1413 16 with with IN cord-005646-xhx9pzhj 1413 17 14 14 CD cord-005646-xhx9pzhj 1413 18 given give VBN cord-005646-xhx9pzhj 1413 19 intravenous intravenous JJ cord-005646-xhx9pzhj 1413 20 salbutamol salbutamol NN cord-005646-xhx9pzhj 1413 21 and and CC cord-005646-xhx9pzhj 1413 22 15 15 CD cord-005646-xhx9pzhj 1413 23 given give VBN cord-005646-xhx9pzhj 1413 24 intravenous intravenous JJ cord-005646-xhx9pzhj 1413 25 saline saline NN cord-005646-xhx9pzhj 1413 26 . . . cord-005646-xhx9pzhj 1414 1 The the DT cord-005646-xhx9pzhj 1414 2 intravenous intravenous JJ cord-005646-xhx9pzhj 1414 3 satbutamol satbutamol NN cord-005646-xhx9pzhj 1414 4 group group NN cord-005646-xhx9pzhj 1414 5 ( ( -LRB- cord-005646-xhx9pzhj 1414 6 IVSG IVSG NNP cord-005646-xhx9pzhj 1414 7 ) ) -RRB- cord-005646-xhx9pzhj 1414 8 showed show VBD cord-005646-xhx9pzhj 1414 9 rapid rapid JJ cord-005646-xhx9pzhj 1414 10 reduction reduction NN cord-005646-xhx9pzhj 1414 11 in in IN cord-005646-xhx9pzhj 1414 12 asthma asthma NN cord-005646-xhx9pzhj 1414 13 severity severity NN cord-005646-xhx9pzhj 1414 14 scale scale NN cord-005646-xhx9pzhj 1414 15 in in IN cord-005646-xhx9pzhj 1414 16 the the DT cord-005646-xhx9pzhj 1414 17 first first JJ cord-005646-xhx9pzhj 1414 18 2 2 CD cord-005646-xhx9pzhj 1414 19 hours hour NNS cord-005646-xhx9pzhj 1414 20 , , , cord-005646-xhx9pzhj 1414 21 with with IN cord-005646-xhx9pzhj 1414 22 reduced reduce VBN cord-005646-xhx9pzhj 1414 23 need need NN cord-005646-xhx9pzhj 1414 24 for for IN cord-005646-xhx9pzhj 1414 25 high high JJ cord-005646-xhx9pzhj 1414 26 frequency frequency NN cord-005646-xhx9pzhj 1414 27 nebuliser nebuliser NN cord-005646-xhx9pzhj 1414 28 therapy therapy NN cord-005646-xhx9pzhj 1414 29 ( ( -LRB- cord-005646-xhx9pzhj 1414 30 _ _ NN cord-005646-xhx9pzhj 1414 31 < < XX cord-005646-xhx9pzhj 1414 32 2 2 CD cord-005646-xhx9pzhj 1414 33 hourly hourly JJ cord-005646-xhx9pzhj 1414 34 ) ) -RRB- cord-005646-xhx9pzhj 1414 35 , , , cord-005646-xhx9pzhj 1414 36 occurring occur VBG cord-005646-xhx9pzhj 1414 37 8.78 8.78 CD cord-005646-xhx9pzhj 1414 38 hours.earlier hours.earlier NN cord-005646-xhx9pzhj 1414 39 . . . cord-005646-xhx9pzhj 1415 1 No no DT cord-005646-xhx9pzhj 1415 2 clinically clinically RB cord-005646-xhx9pzhj 1415 3 significant significant JJ cord-005646-xhx9pzhj 1415 4 side side NN cord-005646-xhx9pzhj 1415 5 - - HYPH cord-005646-xhx9pzhj 1415 6 effects effect NNS cord-005646-xhx9pzhj 1415 7 were be VBD cord-005646-xhx9pzhj 1415 8 found find VBN cord-005646-xhx9pzhj 1415 9 in in IN cord-005646-xhx9pzhj 1415 10 either either DT cord-005646-xhx9pzhj 1415 11 group group NN cord-005646-xhx9pzhj 1415 12 , , , cord-005646-xhx9pzhj 1415 13 although although IN cord-005646-xhx9pzhj 1415 14 , , , cord-005646-xhx9pzhj 1415 15 tremor tremor NN cord-005646-xhx9pzhj 1415 16 more more RBR cord-005646-xhx9pzhj 1415 17 frequent frequent JJ cord-005646-xhx9pzhj 1415 18 in in IN cord-005646-xhx9pzhj 1415 19 the the DT cord-005646-xhx9pzhj 1415 20 [ [ -LRB- cord-005646-xhx9pzhj 1415 21 VSG VSG NNP cord-005646-xhx9pzhj 1415 22 . . . cord-005646-xhx9pzhj 1416 1 Biochemistry biochemistry NN cord-005646-xhx9pzhj 1416 2 and and CC cord-005646-xhx9pzhj 1416 3 salbutamol salbutamol NN cord-005646-xhx9pzhj 1416 4 concentrations concentration NNS cord-005646-xhx9pzhj 1416 5 were be VBD cord-005646-xhx9pzhj 1416 6 similar similar JJ cord-005646-xhx9pzhj 1416 7 in in IN cord-005646-xhx9pzhj 1416 8 both both DT cord-005646-xhx9pzhj 1416 9 groups group NNS cord-005646-xhx9pzhj 1416 10 . . . cord-005646-xhx9pzhj 1417 1 The the DT cord-005646-xhx9pzhj 1417 2 use use NN cord-005646-xhx9pzhj 1417 3 of of IN cord-005646-xhx9pzhj 1417 4 intravenous intravenous JJ cord-005646-xhx9pzhj 1417 5 salbutamol salbutamol NN cord-005646-xhx9pzhj 1417 6 ( ( -LRB- cord-005646-xhx9pzhj 1417 7 I5 I5 NNP cord-005646-xhx9pzhj 1417 8 microgm microgm NNP cord-005646-xhx9pzhj 1417 9 / / SYM cord-005646-xhx9pzhj 1417 10 kg kg NNP cord-005646-xhx9pzhj 1417 11 ) ) -RRB- cord-005646-xhx9pzhj 1417 12 in in IN cord-005646-xhx9pzhj 1417 13 the the DT cord-005646-xhx9pzhj 1417 14 management management NN cord-005646-xhx9pzhj 1417 15 of of IN cord-005646-xhx9pzhj 1417 16 severe severe JJ cord-005646-xhx9pzhj 1417 17 childhood childhood NN cord-005646-xhx9pzhj 1417 18 asthma asthma NN cord-005646-xhx9pzhj 1417 19 is be VBZ cord-005646-xhx9pzhj 1417 20 a a DT cord-005646-xhx9pzhj 1417 21 safe safe JJ cord-005646-xhx9pzhj 1417 22 and and CC cord-005646-xhx9pzhj 1417 23 effective effective JJ cord-005646-xhx9pzhj 1417 24 therapy therapy NN cord-005646-xhx9pzhj 1417 25 with with IN cord-005646-xhx9pzhj 1417 26 no no DT cord-005646-xhx9pzhj 1417 27 significant significant JJ cord-005646-xhx9pzhj 1417 28 side side NN cord-005646-xhx9pzhj 1417 29 - - HYPH cord-005646-xhx9pzhj 1417 30 effects effect NNS cord-005646-xhx9pzhj 1417 31 and and CC cord-005646-xhx9pzhj 1417 32 the the DT cord-005646-xhx9pzhj 1417 33 potential potential NN cord-005646-xhx9pzhj 1417 34 to to TO cord-005646-xhx9pzhj 1417 35 abort abort VB cord-005646-xhx9pzhj 1417 36 severe severe JJ cord-005646-xhx9pzhj 1417 37 asthma asthma NN cord-005646-xhx9pzhj 1417 38 attacks attack NNS cord-005646-xhx9pzhj 1417 39 in in IN cord-005646-xhx9pzhj 1417 40 the the DT cord-005646-xhx9pzhj 1417 41 emergency emergency NN cord-005646-xhx9pzhj 1417 42 department department NN cord-005646-xhx9pzhj 1417 43 . . . cord-005646-xhx9pzhj 1418 1 INTRAVENOUS INTRAVENOUS NNP cord-005646-xhx9pzhj 1418 2 TERBUTALINE TERBUTALINE NNP cord-005646-xhx9pzhj 1418 3 IN in IN cord-005646-xhx9pzhj 1418 4 PICU PICU NNP cord-005646-xhx9pzhj 1419 1 Piva Piva NNP cord-005646-xhx9pzhj 1419 2 J. J. NNP cord-005646-xhx9pzhj 1419 3 , , , cord-005646-xhx9pzhj 1419 4 Amantra Amantra NNP cord-005646-xhx9pzhj 1419 5 S S NNP cord-005646-xhx9pzhj 1419 6 , , , cord-005646-xhx9pzhj 1419 7 Rosso Rosso NNP cord-005646-xhx9pzhj 1419 8 A. a. NN cord-005646-xhx9pzhj 1419 9 , , , cord-005646-xhx9pzhj 1419 10 Zambonato Zambonato NNP cord-005646-xhx9pzhj 1419 11 S S NNP cord-005646-xhx9pzhj 1419 12 , , , cord-005646-xhx9pzhj 1419 13 Giugno Giugno NNP cord-005646-xhx9pzhj 1419 14 K K NNP cord-005646-xhx9pzhj 1419 15 , , , cord-005646-xhx9pzhj 1420 1 Maia Maia NNP cord-005646-xhx9pzhj 1420 2 T. T. NNP cord-005646-xhx9pzhj 1420 3 Introduction introduction NN cord-005646-xhx9pzhj 1420 4 : : : cord-005646-xhx9pzhj 1421 1 The the DT cord-005646-xhx9pzhj 1421 2 admission admission NN cord-005646-xhx9pzhj 1421 3 to to IN cord-005646-xhx9pzhj 1421 4 a a DT cord-005646-xhx9pzhj 1421 5 PICU PICU NNP cord-005646-xhx9pzhj 1421 6 of of IN cord-005646-xhx9pzhj 1421 7 children child NNS cord-005646-xhx9pzhj 1421 8 with with IN cord-005646-xhx9pzhj 1421 9 respiratory respiratory JJ cord-005646-xhx9pzhj 1421 10 failure failure NN cord-005646-xhx9pzhj 1421 11 secondary secondary JJ cord-005646-xhx9pzhj 1421 12 to to IN cord-005646-xhx9pzhj 1421 13 an an DT cord-005646-xhx9pzhj 1421 14 acute acute JJ cord-005646-xhx9pzhj 1421 15 obstructive obstructive JJ cord-005646-xhx9pzhj 1421 16 lower low JJR cord-005646-xhx9pzhj 1421 17 airway airway NN cord-005646-xhx9pzhj 1421 18 disease disease NN cord-005646-xhx9pzhj 1421 19 is be VBZ cord-005646-xhx9pzhj 1421 20 a a DT cord-005646-xhx9pzhj 1421 21 common common JJ cord-005646-xhx9pzhj 1421 22 event event NN cord-005646-xhx9pzhj 1421 23 , , , cord-005646-xhx9pzhj 1421 24 especially especially RB cord-005646-xhx9pzhj 1421 25 during during IN cord-005646-xhx9pzhj 1421 26 winter winter NN cord-005646-xhx9pzhj 1421 27 seasons season NNS cord-005646-xhx9pzhj 1421 28 . . . cord-005646-xhx9pzhj 1422 1 These these DT cord-005646-xhx9pzhj 1422 2 diseases disease NNS cord-005646-xhx9pzhj 1422 3 have have VBP cord-005646-xhx9pzhj 1422 4 several several JJ cord-005646-xhx9pzhj 1422 5 causes cause NNS cord-005646-xhx9pzhj 1422 6 , , , cord-005646-xhx9pzhj 1422 7 but but CC cord-005646-xhx9pzhj 1422 8 most most JJS cord-005646-xhx9pzhj 1422 9 of of IN cord-005646-xhx9pzhj 1422 10 them -PRON- PRP cord-005646-xhx9pzhj 1422 11 ( ( -LRB- cord-005646-xhx9pzhj 1422 12 especially especially RB cord-005646-xhx9pzhj 1422 13 asthma asthma NN cord-005646-xhx9pzhj 1422 14 and and CC cord-005646-xhx9pzhj 1422 15 chronic chronic JJ cord-005646-xhx9pzhj 1422 16 airway airway NN cord-005646-xhx9pzhj 1422 17 disease disease NN cord-005646-xhx9pzhj 1422 18 ) ) -RRB- cord-005646-xhx9pzhj 1422 19 have have VBP cord-005646-xhx9pzhj 1422 20 a a DT cord-005646-xhx9pzhj 1422 21 good good JJ cord-005646-xhx9pzhj 1422 22 response response NN cord-005646-xhx9pzhj 1422 23 to to IN cord-005646-xhx9pzhj 1422 24 the the DT cord-005646-xhx9pzhj 1422 25 administration administration NN cord-005646-xhx9pzhj 1422 26 of of IN cord-005646-xhx9pzhj 1422 27 B2-adrenergic B2-adrenergic NNP cord-005646-xhx9pzhj 1422 28 drugs drug NNS cord-005646-xhx9pzhj 1422 29 . . . cord-005646-xhx9pzhj 1423 1 Objective objective NN cord-005646-xhx9pzhj 1423 2 : : : cord-005646-xhx9pzhj 1423 3 To to TO cord-005646-xhx9pzhj 1423 4 find find VB cord-005646-xhx9pzhj 1423 5 the the DT cord-005646-xhx9pzhj 1423 6 dosis dosis NN cord-005646-xhx9pzhj 1423 7 of of IN cord-005646-xhx9pzhj 1423 8 intravenous intravenous JJ cord-005646-xhx9pzhj 1423 9 terbutaline terbutaline NN cord-005646-xhx9pzhj 1423 10 that that WDT cord-005646-xhx9pzhj 1423 11 is be VBZ cord-005646-xhx9pzhj 1423 12 safe safe JJ cord-005646-xhx9pzhj 1423 13 , , , cord-005646-xhx9pzhj 1423 14 efficient efficient JJ cord-005646-xhx9pzhj 1423 15 and and CC cord-005646-xhx9pzhj 1423 16 with with IN cord-005646-xhx9pzhj 1423 17 minimal minimal JJ cord-005646-xhx9pzhj 1423 18 adverse adverse JJ cord-005646-xhx9pzhj 1423 19 effects effect NNS cord-005646-xhx9pzhj 1423 20 when when WRB cord-005646-xhx9pzhj 1423 21 used use VBN cord-005646-xhx9pzhj 1423 22 in in IN cord-005646-xhx9pzhj 1423 23 children child NNS cord-005646-xhx9pzhj 1423 24 admitted admit VBN cord-005646-xhx9pzhj 1423 25 to to IN cord-005646-xhx9pzhj 1423 26 a a DT cord-005646-xhx9pzhj 1423 27 PICU PICU NNP cord-005646-xhx9pzhj 1423 28 with with IN cord-005646-xhx9pzhj 1423 29 acute acute JJ cord-005646-xhx9pzhj 1423 30 obstructive obstructive JJ cord-005646-xhx9pzhj 1423 31 lower low JJR cord-005646-xhx9pzhj 1423 32 airway airway NN cord-005646-xhx9pzhj 1423 33 disease disease NN cord-005646-xhx9pzhj 1423 34 and and CC cord-005646-xhx9pzhj 1423 35 respiratory respiratory JJ cord-005646-xhx9pzhj 1423 36 failure failure NN cord-005646-xhx9pzhj 1423 37 . . . cord-005646-xhx9pzhj 1424 1 Material material NN cord-005646-xhx9pzhj 1424 2 and and CC cord-005646-xhx9pzhj 1424 3 Methods method NNS cord-005646-xhx9pzhj 1425 1 : : : cord-005646-xhx9pzhj 1425 2 We -PRON- PRP cord-005646-xhx9pzhj 1425 3 study study VBP cord-005646-xhx9pzhj 1425 4 the the DT cord-005646-xhx9pzhj 1425 5 records record NNS cord-005646-xhx9pzhj 1425 6 of of IN cord-005646-xhx9pzhj 1425 7 all all DT cord-005646-xhx9pzhj 1425 8 children child NNS cord-005646-xhx9pzhj 1425 9 that that WDT cord-005646-xhx9pzhj 1425 10 were be VBD cord-005646-xhx9pzhj 1425 11 admitted admit VBN cord-005646-xhx9pzhj 1425 12 to to IN cord-005646-xhx9pzhj 1425 13 our -PRON- PRP$ cord-005646-xhx9pzhj 1425 14 PICU PICU NNP cord-005646-xhx9pzhj 1425 15 during during IN cord-005646-xhx9pzhj 1425 16 the the DT cord-005646-xhx9pzhj 1425 17 winter winter NN cord-005646-xhx9pzhj 1425 18 of of IN cord-005646-xhx9pzhj 1425 19 1995 1995 CD cord-005646-xhx9pzhj 1425 20 . . . cord-005646-xhx9pzhj 1426 1 Only only RB cord-005646-xhx9pzhj 1426 2 the the DT cord-005646-xhx9pzhj 1426 3 patients patient NNS cord-005646-xhx9pzhj 1426 4 that that WDT cord-005646-xhx9pzhj 1426 5 had have VBD cord-005646-xhx9pzhj 1426 6 respiratory respiratory JJ cord-005646-xhx9pzhj 1426 7 failure failure NN cord-005646-xhx9pzhj 1426 8 and and CC cord-005646-xhx9pzhj 1426 9 acute acute JJ cord-005646-xhx9pzhj 1426 10 lower low JJR cord-005646-xhx9pzhj 1426 11 airway airway NN cord-005646-xhx9pzhj 1426 12 disease disease NN cord-005646-xhx9pzhj 1426 13 and and CC cord-005646-xhx9pzhj 1426 14 who who WP cord-005646-xhx9pzhj 1426 15 needed need VBD cord-005646-xhx9pzhj 1426 16 the the DT cord-005646-xhx9pzhj 1426 17 use use NN cord-005646-xhx9pzhj 1426 18 of of IN cord-005646-xhx9pzhj 1426 19 IV IV NNP cord-005646-xhx9pzhj 1426 20 terbutaline terbutaline NNP cord-005646-xhx9pzhj 1426 21 were be VBD cord-005646-xhx9pzhj 1426 22 selected select VBN cord-005646-xhx9pzhj 1426 23 . . . cord-005646-xhx9pzhj 1427 1 The the DT cord-005646-xhx9pzhj 1427 2 records record NNS cord-005646-xhx9pzhj 1427 3 were be VBD cord-005646-xhx9pzhj 1427 4 divided divide VBN cord-005646-xhx9pzhj 1427 5 in in IN cord-005646-xhx9pzhj 1427 6 two two CD cord-005646-xhx9pzhj 1427 7 groups group NNS cord-005646-xhx9pzhj 1427 8 : : : cord-005646-xhx9pzhj 1427 9 less less JJR cord-005646-xhx9pzhj 1427 10 than than IN cord-005646-xhx9pzhj 1427 11 12 12 CD cord-005646-xhx9pzhj 1427 12 months month NNS cord-005646-xhx9pzhj 1427 13 and and CC cord-005646-xhx9pzhj 1427 14 more more JJR cord-005646-xhx9pzhj 1427 15 than than IN cord-005646-xhx9pzhj 1427 16 a a DT cord-005646-xhx9pzhj 1427 17 year year NN cord-005646-xhx9pzhj 1427 18 old old JJ cord-005646-xhx9pzhj 1427 19 These these DT cord-005646-xhx9pzhj 1427 20 two two CD cord-005646-xhx9pzhj 1427 21 groups group NNS cord-005646-xhx9pzhj 1427 22 were be VBD cord-005646-xhx9pzhj 1427 23 compared compare VBN cord-005646-xhx9pzhj 1427 24 in in IN cord-005646-xhx9pzhj 1427 25 the the DT cord-005646-xhx9pzhj 1427 26 following follow VBG cord-005646-xhx9pzhj 1427 27 aspects aspect NNS cord-005646-xhx9pzhj 1427 28 : : : cord-005646-xhx9pzhj 1427 29 the the DT cord-005646-xhx9pzhj 1427 30 minimal minimal JJ cord-005646-xhx9pzhj 1427 31 and and CC cord-005646-xhx9pzhj 1427 32 maximal maximal JJ cord-005646-xhx9pzhj 1427 33 dosis dosis NN cord-005646-xhx9pzhj 1427 34 , , , cord-005646-xhx9pzhj 1427 35 and and CC cord-005646-xhx9pzhj 1427 36 the the DT cord-005646-xhx9pzhj 1427 37 length length NN cord-005646-xhx9pzhj 1427 38 of of IN cord-005646-xhx9pzhj 1427 39 time time NN cord-005646-xhx9pzhj 1427 40 of of IN cord-005646-xhx9pzhj 1427 41 use use NN cord-005646-xhx9pzhj 1427 42 of of IN cord-005646-xhx9pzhj 1427 43 IV IV NNP cord-005646-xhx9pzhj 1427 44 terbutaline terbutaline NN cord-005646-xhx9pzhj 1427 45 , , , cord-005646-xhx9pzhj 1427 46 frequency frequency NN cord-005646-xhx9pzhj 1427 47 of of IN cord-005646-xhx9pzhj 1427 48 tachycardia tachycardia NN cord-005646-xhx9pzhj 1427 49 , , , cord-005646-xhx9pzhj 1427 50 hypokalemia hypokalemia NN cord-005646-xhx9pzhj 1427 51 , , , cord-005646-xhx9pzhj 1427 52 and and CC cord-005646-xhx9pzhj 1427 53 mechanical mechanical JJ cord-005646-xhx9pzhj 1427 54 ventilation ventilation NN cord-005646-xhx9pzhj 1427 55 . . . cord-005646-xhx9pzhj 1428 1 To to TO cord-005646-xhx9pzhj 1428 2 establish establish VB cord-005646-xhx9pzhj 1428 3 any any DT cord-005646-xhx9pzhj 1428 4 difference difference NN cord-005646-xhx9pzhj 1428 5 in in IN cord-005646-xhx9pzhj 1428 6 the the DT cord-005646-xhx9pzhj 1428 7 two two CD cord-005646-xhx9pzhj 1428 8 groups group NNS cord-005646-xhx9pzhj 1428 9 we -PRON- PRP cord-005646-xhx9pzhj 1428 10 use use VBP cord-005646-xhx9pzhj 1428 11 the the DT cord-005646-xhx9pzhj 1428 12 T T NNP cord-005646-xhx9pzhj 1428 13 exact exact JJ cord-005646-xhx9pzhj 1428 14 test test NN cord-005646-xhx9pzhj 1428 15 of of IN cord-005646-xhx9pzhj 1428 16 Fisher Fisher NNP cord-005646-xhx9pzhj 1428 17 and and CC cord-005646-xhx9pzhj 1428 18 X2 X2 NNP cord-005646-xhx9pzhj 1428 19 , , , cord-005646-xhx9pzhj 1428 20 with with IN cord-005646-xhx9pzhj 1428 21 p p NN cord-005646-xhx9pzhj 1428 22 < < XX cord-005646-xhx9pzhj 1428 23 0.05 0.05 CD cord-005646-xhx9pzhj 1428 24 , , , cord-005646-xhx9pzhj 1428 25 Results result NNS cord-005646-xhx9pzhj 1428 26 : : : cord-005646-xhx9pzhj 1428 27 During during IN cord-005646-xhx9pzhj 1428 28 the the DT cord-005646-xhx9pzhj 1428 29 period period NN cord-005646-xhx9pzhj 1428 30 of of IN cord-005646-xhx9pzhj 1428 31 study study NN cord-005646-xhx9pzhj 1428 32 were be VBD cord-005646-xhx9pzhj 1428 33 admitted admit VBN cord-005646-xhx9pzhj 1428 34 367 367 CD cord-005646-xhx9pzhj 1428 35 patients patient NNS cord-005646-xhx9pzhj 1428 36 to to IN cord-005646-xhx9pzhj 1428 37 the the DT cord-005646-xhx9pzhj 1428 38 PICU PICU NNP cord-005646-xhx9pzhj 1428 39 , , , cord-005646-xhx9pzhj 1428 40 and and CC cord-005646-xhx9pzhj 1428 41 38 38 CD cord-005646-xhx9pzhj 1428 42 ( ( -LRB- cord-005646-xhx9pzhj 1428 43 10,3 10,3 CD cord-005646-xhx9pzhj 1428 44 % % NN cord-005646-xhx9pzhj 1428 45 ) ) -RRB- cord-005646-xhx9pzhj 1428 46 of of IN cord-005646-xhx9pzhj 1428 47 them -PRON- PRP cord-005646-xhx9pzhj 1428 48 used use VBN cord-005646-xhx9pzhj 1428 49 of of IN cord-005646-xhx9pzhj 1428 50 iv iv NNP cord-005646-xhx9pzhj 1428 51 terbutaline terbutaline NNP cord-005646-xhx9pzhj 1428 52 . . . cord-005646-xhx9pzhj 1429 1 The the DT cord-005646-xhx9pzhj 1429 2 mean mean JJ cord-005646-xhx9pzhj 1429 3 age age NN cord-005646-xhx9pzhj 1429 4 was be VBD cord-005646-xhx9pzhj 1429 5 14.2 14.2 CD cord-005646-xhx9pzhj 1429 6 +12.2 +12.2 CD cord-005646-xhx9pzhj 1429 7 month month NN cord-005646-xhx9pzhj 1429 8 , , , cord-005646-xhx9pzhj 1429 9 used use VBD cord-005646-xhx9pzhj 1429 10 iv iv NNP cord-005646-xhx9pzhj 1429 11 terbutaline terbutaline NN cord-005646-xhx9pzhj 1429 12 during during IN cord-005646-xhx9pzhj 1429 13 7.24 7.24 CD cord-005646-xhx9pzhj 1429 14 +3.75 +3.75 NNP cord-005646-xhx9pzhj 1429 15 days day NNS cord-005646-xhx9pzhj 1429 16 ( ( -LRB- cord-005646-xhx9pzhj 1429 17 0.5 0.5 CD cord-005646-xhx9pzhj 1429 18 to to TO cord-005646-xhx9pzhj 1429 19 17 17 CD cord-005646-xhx9pzhj 1429 20 days day NNS cord-005646-xhx9pzhj 1429 21 ) ) -RRB- cord-005646-xhx9pzhj 1429 22 , , , cord-005646-xhx9pzhj 1429 23 the the DT cord-005646-xhx9pzhj 1429 24 initial initial JJ cord-005646-xhx9pzhj 1429 25 rate rate NN cord-005646-xhx9pzhj 1429 26 was be VBD cord-005646-xhx9pzhj 1429 27 0.55 0.55 CD cord-005646-xhx9pzhj 1430 1 +0.26p +0.26p NNP cord-005646-xhx9pzhj 1431 1 ~g ~g NNP cord-005646-xhx9pzhj 1431 2 / / SYM cord-005646-xhx9pzhj 1431 3 kg kg NNP cord-005646-xhx9pzhj 1431 4 / / SYM cord-005646-xhx9pzhj 1431 5 min min NNP cord-005646-xhx9pzhj 1431 6 , , , cord-005646-xhx9pzhj 1431 7 and and CC cord-005646-xhx9pzhj 1431 8 the the DT cord-005646-xhx9pzhj 1431 9 means mean NNS cord-005646-xhx9pzhj 1431 10 of of IN cord-005646-xhx9pzhj 1431 11 therapeutic therapeutic JJ cord-005646-xhx9pzhj 1431 12 dosis dosis NNP cord-005646-xhx9pzhj 1431 13 was be VBD cord-005646-xhx9pzhj 1431 14 2.48 2.48 CD cord-005646-xhx9pzhj 1431 15 + + SYM cord-005646-xhx9pzhj 1431 16 l.181~g l.181~g NN cord-005646-xhx9pzhj 1432 1 /kg /kg NFP cord-005646-xhx9pzhj 1432 2 / / SYM cord-005646-xhx9pzhj 1432 3 min min NN cord-005646-xhx9pzhj 1432 4 ( ( -LRB- cord-005646-xhx9pzhj 1432 5 ranged range VBD cord-005646-xhx9pzhj 1432 6 from from IN cord-005646-xhx9pzhj 1432 7 0.5 0.5 CD cord-005646-xhx9pzhj 1432 8 to to IN cord-005646-xhx9pzhj 1432 9 4.4 4.4 CD cord-005646-xhx9pzhj 1432 10 ) ) -RRB- cord-005646-xhx9pzhj 1432 11 . . . cord-005646-xhx9pzhj 1433 1 Twelve twelve CD cord-005646-xhx9pzhj 1433 2 ( ( -LRB- cord-005646-xhx9pzhj 1433 3 31.5 31.5 CD cord-005646-xhx9pzhj 1433 4 % % NN cord-005646-xhx9pzhj 1433 5 ) ) -RRB- cord-005646-xhx9pzhj 1433 6 patients patient NNS cord-005646-xhx9pzhj 1433 7 had have VBD cord-005646-xhx9pzhj 1433 8 tachycardia tachycardia VBN cord-005646-xhx9pzhj 1433 9 art art NN cord-005646-xhx9pzhj 1433 10 obstacle obstacle NN cord-005646-xhx9pzhj 1433 11 to to IN cord-005646-xhx9pzhj 1433 12 the the DT cord-005646-xhx9pzhj 1433 13 increases increase NNS cord-005646-xhx9pzhj 1433 14 in in IN cord-005646-xhx9pzhj 1433 15 the the DT cord-005646-xhx9pzhj 1433 16 rate rate NN cord-005646-xhx9pzhj 1433 17 of of IN cord-005646-xhx9pzhj 1433 18 use use NN cord-005646-xhx9pzhj 1433 19 of of IN cord-005646-xhx9pzhj 1433 20 iv iv NNP cord-005646-xhx9pzhj 1433 21 terbutaline terbutaline NN cord-005646-xhx9pzhj 1433 22 during during IN cord-005646-xhx9pzhj 1433 23 any any DT cord-005646-xhx9pzhj 1433 24 time time NN cord-005646-xhx9pzhj 1433 25 . . . cord-005646-xhx9pzhj 1434 1 Mechanical mechanical JJ cord-005646-xhx9pzhj 1434 2 ventilation ventilation NN cord-005646-xhx9pzhj 1434 3 was be VBD cord-005646-xhx9pzhj 1434 4 necessary necessary JJ cord-005646-xhx9pzhj 1434 5 in in IN cord-005646-xhx9pzhj 1434 6 22 22 CD cord-005646-xhx9pzhj 1434 7 patients patient NNS cord-005646-xhx9pzhj 1434 8 ( ( -LRB- cord-005646-xhx9pzhj 1434 9 57.8 57.8 CD cord-005646-xhx9pzhj 1434 10 % % NN cord-005646-xhx9pzhj 1434 11 ) ) -RRB- cord-005646-xhx9pzhj 1434 12 and and CC cord-005646-xhx9pzhj 1434 13 11 11 CD cord-005646-xhx9pzhj 1434 14 ( ( -LRB- cord-005646-xhx9pzhj 1434 15 28.9 28.9 CD cord-005646-xhx9pzhj 1434 16 % % NN cord-005646-xhx9pzhj 1434 17 ) ) -RRB- cord-005646-xhx9pzhj 1434 18 patients patient NNS cord-005646-xhx9pzhj 1434 19 died die VBD cord-005646-xhx9pzhj 1434 20 . . . cord-005646-xhx9pzhj 1435 1 The the DT cord-005646-xhx9pzhj 1435 2 children child NNS cord-005646-xhx9pzhj 1435 3 under under IN cord-005646-xhx9pzhj 1435 4 1 1 CD cord-005646-xhx9pzhj 1435 5 year year NN cord-005646-xhx9pzhj 1435 6 of of IN cord-005646-xhx9pzhj 1435 7 age age NN cord-005646-xhx9pzhj 1435 8 used use VBD cord-005646-xhx9pzhj 1435 9 initial initial JJ cord-005646-xhx9pzhj 1435 10 dosis dosis NNP cord-005646-xhx9pzhj 1435 11 of of IN cord-005646-xhx9pzhj 1435 12 iv iv NNP cord-005646-xhx9pzhj 1435 13 terbutaline terbutaline NNP cord-005646-xhx9pzhj 1435 14 lower low JJR cord-005646-xhx9pzhj 1435 15 than than IN cord-005646-xhx9pzhj 1435 16 the the DT cord-005646-xhx9pzhj 1435 17 children child NNS cord-005646-xhx9pzhj 1435 18 up up IN cord-005646-xhx9pzhj 1435 19 of of IN cord-005646-xhx9pzhj 1435 20 1 1 CD cord-005646-xhx9pzhj 1435 21 year year NN cord-005646-xhx9pzhj 1435 22 old old JJ cord-005646-xhx9pzhj 1435 23 ( ( -LRB- cord-005646-xhx9pzhj 1435 24 0.45 0.45 CD cord-005646-xhx9pzhj 1435 25 p.g/ p.g/ NNP cord-005646-xhx9pzhj 1435 26 kghnin kghnin NNS cord-005646-xhx9pzhj 1436 1 x x SYM cord-005646-xhx9pzhj 1436 2 0.57 0.57 CD cord-005646-xhx9pzhj 1437 1 ~tg ~tg NNP cord-005646-xhx9pzhj 1437 2 & & CC cord-005646-xhx9pzhj 1437 3 g g NN cord-005646-xhx9pzhj 1437 4 / / SYM cord-005646-xhx9pzhj 1437 5 rain rain NN cord-005646-xhx9pzhj 1437 6 , , , cord-005646-xhx9pzhj 1437 7 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 1437 8 ) ) -RRB- cord-005646-xhx9pzhj 1437 9 , , . cord-005646-xhx9pzhj 1438 1 but but CC cord-005646-xhx9pzhj 1438 2 without without IN cord-005646-xhx9pzhj 1438 3 difference difference NN cord-005646-xhx9pzhj 1438 4 in in IN cord-005646-xhx9pzhj 1438 5 the the DT cord-005646-xhx9pzhj 1438 6 length length NN cord-005646-xhx9pzhj 1438 7 of of IN cord-005646-xhx9pzhj 1438 8 use use NN cord-005646-xhx9pzhj 1438 9 , , , cord-005646-xhx9pzhj 1438 10 the the DT cord-005646-xhx9pzhj 1438 11 maximal maximal JJ cord-005646-xhx9pzhj 1438 12 dosis dosis NNP cord-005646-xhx9pzhj 1438 13 , , , cord-005646-xhx9pzhj 1438 14 the the DT cord-005646-xhx9pzhj 1438 15 rate rate NN cord-005646-xhx9pzhj 1438 16 of of IN cord-005646-xhx9pzhj 1438 17 mechanical mechanical JJ cord-005646-xhx9pzhj 1438 18 ventilation ventilation NN cord-005646-xhx9pzhj 1438 19 and and CC cord-005646-xhx9pzhj 1438 20 tachycardia tachycardia NN cord-005646-xhx9pzhj 1438 21 . . . cord-005646-xhx9pzhj 1439 1 The the DT cord-005646-xhx9pzhj 1439 2 frequency frequency NN cord-005646-xhx9pzhj 1439 3 of of IN cord-005646-xhx9pzhj 1439 4 hypokalemia hypokalemia NN cord-005646-xhx9pzhj 1439 5 was be VBD cord-005646-xhx9pzhj 1439 6 most most RBS cord-005646-xhx9pzhj 1439 7 common common JJ cord-005646-xhx9pzhj 1439 8 in in IN cord-005646-xhx9pzhj 1439 9 the the DT cord-005646-xhx9pzhj 1439 10 group group NN cord-005646-xhx9pzhj 1439 11 of of IN cord-005646-xhx9pzhj 1439 12 children child NNS cord-005646-xhx9pzhj 1439 13 under under IN cord-005646-xhx9pzhj 1439 14 year year NN cord-005646-xhx9pzhj 1439 15 of of IN cord-005646-xhx9pzhj 1439 16 age age NN cord-005646-xhx9pzhj 1439 17 . . . cord-005646-xhx9pzhj 1440 1 Acute acute JJ cord-005646-xhx9pzhj 1440 2 respiratory respiratory JJ cord-005646-xhx9pzhj 1440 3 failure failure NN cord-005646-xhx9pzhj 1440 4 during during IN cord-005646-xhx9pzhj 1440 5 status status NN cord-005646-xhx9pzhj 1440 6 asthmaticus asthmaticus NN cord-005646-xhx9pzhj 1440 7 may may MD cord-005646-xhx9pzhj 1440 8 require require VB cord-005646-xhx9pzhj 1440 9 mechanical mechanical JJ cord-005646-xhx9pzhj 1440 10 ventilation ventilation NN cord-005646-xhx9pzhj 1440 11 . . . cord-005646-xhx9pzhj 1441 1 Current current JJ cord-005646-xhx9pzhj 1441 2 therapy therapy NN cord-005646-xhx9pzhj 1441 3 includes include VBZ cord-005646-xhx9pzhj 1441 4 paralysis paralysis NN cord-005646-xhx9pzhj 1441 5 , , , cord-005646-xhx9pzhj 1441 6 pressure pressure NN cord-005646-xhx9pzhj 1441 7 control control NN cord-005646-xhx9pzhj 1441 8 ventilation ventilation NN cord-005646-xhx9pzhj 1441 9 ( ( -LRB- cord-005646-xhx9pzhj 1441 10 PCV pcv NN cord-005646-xhx9pzhj 1441 11 ) ) -RRB- cord-005646-xhx9pzhj 1441 12 and and CC cord-005646-xhx9pzhj 1441 13 permissive permissive JJ cord-005646-xhx9pzhj 1441 14 hypercapnia hypercapnia NN cord-005646-xhx9pzhj 1441 15 to to TO cord-005646-xhx9pzhj 1441 16 limit limit VB cord-005646-xhx9pzhj 1441 17 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1441 18 barotranma barotranma NN cord-005646-xhx9pzhj 1441 19 and and CC cord-005646-xhx9pzhj 1441 20 its -PRON- PRP$ cord-005646-xhx9pzhj 1441 21 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 1441 22 consequences consequence NNS cord-005646-xhx9pzhj 1441 23 . . . cord-005646-xhx9pzhj 1442 1 Asthmatic asthmatic JJ cord-005646-xhx9pzhj 1442 2 children child NNS cord-005646-xhx9pzhj 1442 3 exert exert VBP cord-005646-xhx9pzhj 1442 4 a a DT cord-005646-xhx9pzhj 1442 5 significant significant JJ cord-005646-xhx9pzhj 1442 6 amount amount NN cord-005646-xhx9pzhj 1442 7 of of IN cord-005646-xhx9pzhj 1442 8 respiratory respiratory JJ cord-005646-xhx9pzhj 1442 9 effort effort NN cord-005646-xhx9pzhj 1442 10 during during IN cord-005646-xhx9pzhj 1442 11 exhalation exhalation NN cord-005646-xhx9pzhj 1442 12 . . . cord-005646-xhx9pzhj 1443 1 With with IN cord-005646-xhx9pzhj 1443 2 paralysis paralysis NN cord-005646-xhx9pzhj 1443 3 , , , cord-005646-xhx9pzhj 1443 4 this this DT cord-005646-xhx9pzhj 1443 5 expiratory expiratory JJ cord-005646-xhx9pzhj 1443 6 effort effort NN cord-005646-xhx9pzhj 1443 7 is be VBZ cord-005646-xhx9pzhj 1443 8 lost lose VBN cord-005646-xhx9pzhj 1443 9 . . . cord-005646-xhx9pzhj 1444 1 Unloading unload VBG cord-005646-xhx9pzhj 1444 2 the the DT cord-005646-xhx9pzhj 1444 3 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1444 4 work work NN cord-005646-xhx9pzhj 1444 5 of of IN cord-005646-xhx9pzhj 1444 6 breathing breathe VBG cord-005646-xhx9pzhj 1444 7 while while IN cord-005646-xhx9pzhj 1444 8 maintaining maintain VBG cord-005646-xhx9pzhj 1444 9 the the DT cord-005646-xhx9pzhj 1444 10 patient patient NN cord-005646-xhx9pzhj 1444 11 's 's POS cord-005646-xhx9pzhj 1444 12 expiratory expiratory JJ cord-005646-xhx9pzhj 1444 13 eftbrt eftbrt NN cord-005646-xhx9pzhj 1444 14 using use VBG cord-005646-xhx9pzhj 1444 15 pressure pressure NN cord-005646-xhx9pzhj 1444 16 support support NN cord-005646-xhx9pzhj 1444 17 ventilation ventilation NN cord-005646-xhx9pzhj 1444 18 ( ( -LRB- cord-005646-xhx9pzhj 1444 19 PSV PSV NNP cord-005646-xhx9pzhj 1444 20 ) ) -RRB- cord-005646-xhx9pzhj 1444 21 , , , cord-005646-xhx9pzhj 1444 22 may may MD cord-005646-xhx9pzhj 1444 23 be be VB cord-005646-xhx9pzhj 1444 24 beneficial beneficial JJ cord-005646-xhx9pzhj 1444 25 . . . cord-005646-xhx9pzhj 1445 1 Methods method NNS cord-005646-xhx9pzhj 1445 2 : : : cord-005646-xhx9pzhj 1445 3 Children child NNS cord-005646-xhx9pzhj 1445 4 receiving receive VBG cord-005646-xhx9pzhj 1445 5 PCV PCV NNP cord-005646-xhx9pzhj 1445 6 ( ( -LRB- cord-005646-xhx9pzhj 1445 7 peak peak JJ cord-005646-xhx9pzhj 1445 8 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1445 9 pressure pressure NN cord-005646-xhx9pzhj 1445 10 ( ( -LRB- cord-005646-xhx9pzhj 1445 11 PIP PIP NNP cord-005646-xhx9pzhj 1445 12 ) ) -RRB- cord-005646-xhx9pzhj 1445 13 = = NFP cord-005646-xhx9pzhj 1446 1 4 4 LS cord-005646-xhx9pzhj 1446 2 kPa kPa NNS cord-005646-xhx9pzhj 1446 3 . . . cord-005646-xhx9pzhj 1447 1 rate rate NN cord-005646-xhx9pzhj 1447 2 10 10 CD cord-005646-xhx9pzhj 1447 3 breaths breath NNS cord-005646-xhx9pzhj 1447 4 / / SYM cord-005646-xhx9pzhj 1447 5 min min NN cord-005646-xhx9pzhj 1447 6 ) ) -RRB- cord-005646-xhx9pzhj 1447 7 and and CC cord-005646-xhx9pzhj 1447 8 PCO2 PCO2 NNP cord-005646-xhx9pzhj 1447 9 > > XX cord-005646-xhx9pzhj 1448 1 8 8 CD cord-005646-xhx9pzhj 1448 2 kPa kPa NNS cord-005646-xhx9pzhj 1448 3 were be VBD cord-005646-xhx9pzhj 1448 4 switched switch VBN cord-005646-xhx9pzhj 1448 5 to to IN cord-005646-xhx9pzhj 1448 6 PSV PSV NNP cord-005646-xhx9pzhj 1448 7 . . . cord-005646-xhx9pzhj 1449 1 Children child NNS cord-005646-xhx9pzhj 1449 2 were be VBD cord-005646-xhx9pzhj 1449 3 initially initially RB cord-005646-xhx9pzhj 1449 4 ventilated ventilate VBN cord-005646-xhx9pzhj 1449 5 with with IN cord-005646-xhx9pzhj 1449 6 PSV PSV NNP cord-005646-xhx9pzhj 1449 7 3.7 3.7 CD cord-005646-xhx9pzhj 1449 8 kPa kPa NNS cord-005646-xhx9pzhj 1449 9 and and CC cord-005646-xhx9pzhj 1449 10 PEEP peep NN cord-005646-xhx9pzhj 1449 11 = = NFP cord-005646-xhx9pzhj 1450 1 0.3 0.3 CD cord-005646-xhx9pzhj 1450 2 kPa kPa NNP cord-005646-xhx9pzhj 1450 3 ( ( -LRB- cord-005646-xhx9pzhj 1450 4 Servo Servo NNP cord-005646-xhx9pzhj 1450 5 900C 900C NNP cord-005646-xhx9pzhj 1450 6 ) ) -RRB- cord-005646-xhx9pzhj 1450 7 . . . cord-005646-xhx9pzhj 1451 1 All all DT cord-005646-xhx9pzhj 1451 2 children child NNS cord-005646-xhx9pzhj 1451 3 received receive VBD cord-005646-xhx9pzhj 1451 4 beta beta JJ cord-005646-xhx9pzhj 1451 5 agonist agonist NN cord-005646-xhx9pzhj 1451 6 therapy therapy NN cord-005646-xhx9pzhj 1451 7 , , , cord-005646-xhx9pzhj 1451 8 ipratropium ipratropium NN cord-005646-xhx9pzhj 1451 9 and and CC cord-005646-xhx9pzhj 1451 10 anesthesia anesthesia NN cord-005646-xhx9pzhj 1451 11 with with IN cord-005646-xhx9pzhj 1451 12 ketamine ketamine NN cord-005646-xhx9pzhj 1451 13 or or CC cord-005646-xhx9pzhj 1451 14 inhalational inhalational JJ cord-005646-xhx9pzhj 1451 15 anesthesia anesthesia NN cord-005646-xhx9pzhj 1451 16 , , , cord-005646-xhx9pzhj 1451 17 and and CC cord-005646-xhx9pzhj 1451 18 were be VBD cord-005646-xhx9pzhj 1451 19 breathing breathe VBG cord-005646-xhx9pzhj 1451 20 spontaneously spontaneously RB cord-005646-xhx9pzhj 1451 21 . . . cord-005646-xhx9pzhj 1452 1 Respiratory respiratory JJ cord-005646-xhx9pzhj 1452 2 parameters parameter NNS cord-005646-xhx9pzhj 1452 3 and and CC cord-005646-xhx9pzhj 1452 4 blood blood NN cord-005646-xhx9pzhj 1452 5 gases gas NNS cord-005646-xhx9pzhj 1452 6 are be VBP cord-005646-xhx9pzhj 1452 7 shown show VBN cord-005646-xhx9pzhj 1452 8 be be VB cord-005646-xhx9pzhj 1452 9 ~ ~ NFP cord-005646-xhx9pzhj 1452 10 bre bre NNP cord-005646-xhx9pzhj 1452 11 PSV PSV NNP cord-005646-xhx9pzhj 1452 12 , , , cord-005646-xhx9pzhj 1452 13 within within IN cord-005646-xhx9pzhj 1452 14 30 30 CD cord-005646-xhx9pzhj 1452 15 minutes minute NNS cord-005646-xhx9pzhj 1452 16 ( ( -LRB- cord-005646-xhx9pzhj 1452 17 Start start VB cord-005646-xhx9pzhj 1452 18 ) ) -RRB- cord-005646-xhx9pzhj 1452 19 and and CC cord-005646-xhx9pzhj 1452 20 when when WRB cord-005646-xhx9pzhj 1452 21 the the DT cord-005646-xhx9pzhj 1452 22 pH pH NNP cord-005646-xhx9pzhj 1452 23 had have VBD cord-005646-xhx9pzhj 1452 24 normalized normalize VBN cord-005646-xhx9pzhj 1452 25 ( ( -LRB- cord-005646-xhx9pzhj 1452 26 During during IN cord-005646-xhx9pzhj 1452 27 ) ) -RRB- cord-005646-xhx9pzhj 1452 28 . . . cord-005646-xhx9pzhj 1453 1 Data datum NNS cord-005646-xhx9pzhj 1453 2 are be VBP cord-005646-xhx9pzhj 1453 3 presented present VBN cord-005646-xhx9pzhj 1453 4 as as IN cord-005646-xhx9pzhj 1453 5 median median NN cord-005646-xhx9pzhj 1453 6 and and CC cord-005646-xhx9pzhj 1453 7 range range NN cord-005646-xhx9pzhj 1453 8 , , , cord-005646-xhx9pzhj 1454 1 * * NFP cord-005646-xhx9pzhj 1454 2 p p XX cord-005646-xhx9pzhj 1454 3 < < XX cord-005646-xhx9pzhj 1454 4 0.03 0.03 CD cord-005646-xhx9pzhj 1454 5 compared compare VBN cord-005646-xhx9pzhj 1454 6 to to IN cord-005646-xhx9pzhj 1454 7 before before IN cord-005646-xhx9pzhj 1454 8 PSV PSV NNP cord-005646-xhx9pzhj 1454 9 . . . cord-005646-xhx9pzhj 1455 1 Results result NNS cord-005646-xhx9pzhj 1455 2 : : : cord-005646-xhx9pzhj 1456 1 Children child NNS cord-005646-xhx9pzhj 1456 2 with with IN cord-005646-xhx9pzhj 1456 3 hypercarbia hypercarbia NN cord-005646-xhx9pzhj 1456 4 during during IN cord-005646-xhx9pzhj 1456 5 PCV PCV NNP cord-005646-xhx9pzhj 1456 6 responded respond VBD cord-005646-xhx9pzhj 1456 7 to to IN cord-005646-xhx9pzhj 1456 8 PSV PSV NNP cord-005646-xhx9pzhj 1456 9 , , , cord-005646-xhx9pzhj 1456 10 normalizing normalize VBG cord-005646-xhx9pzhj 1456 11 PCOs pco NNS cord-005646-xhx9pzhj 1456 12 and and CC cord-005646-xhx9pzhj 1456 13 pH ph NN cord-005646-xhx9pzhj 1456 14 within within IN cord-005646-xhx9pzhj 1456 15 6 6 CD cord-005646-xhx9pzhj 1456 16 hours hour NNS cord-005646-xhx9pzhj 1456 17 . . . cord-005646-xhx9pzhj 1457 1 The the DT cord-005646-xhx9pzhj 1457 2 mean mean JJ cord-005646-xhx9pzhj 1457 3 respiratory respiratory JJ cord-005646-xhx9pzhj 1457 4 rate rate NN cord-005646-xhx9pzhj 1457 5 decreased decrease VBD cord-005646-xhx9pzhj 1457 6 from from IN cord-005646-xhx9pzhj 1457 7 a a DT cord-005646-xhx9pzhj 1457 8 median median NN cord-005646-xhx9pzhj 1457 9 of of IN cord-005646-xhx9pzhj 1457 10 45 45 CD cord-005646-xhx9pzhj 1457 11 ( ( -LRB- cord-005646-xhx9pzhj 1457 12 31 31 CD cord-005646-xhx9pzhj 1457 13 - - SYM cord-005646-xhx9pzhj 1457 14 46 46 CD cord-005646-xhx9pzhj 1457 15 ) ) -RRB- cord-005646-xhx9pzhj 1457 16 to to IN cord-005646-xhx9pzhj 1457 17 35 35 CD cord-005646-xhx9pzhj 1457 18 ( ( -LRB- cord-005646-xhx9pzhj 1457 19 22 22 CD cord-005646-xhx9pzhj 1457 20 - - SYM cord-005646-xhx9pzhj 1457 21 35 35 CD cord-005646-xhx9pzhj 1457 22 ) ) -RRB- cord-005646-xhx9pzhj 1457 23 while while IN cord-005646-xhx9pzhj 1457 24 the the DT cord-005646-xhx9pzhj 1457 25 PIP PIP NNP cord-005646-xhx9pzhj 1457 26 was be VBD cord-005646-xhx9pzhj 1457 27 decreased decrease VBN cord-005646-xhx9pzhj 1457 28 to to IN cord-005646-xhx9pzhj 1457 29 3.2 3.2 CD cord-005646-xhx9pzhj 1457 30 ( ( -LRB- cord-005646-xhx9pzhj 1457 31 2.5 2.5 CD cord-005646-xhx9pzhj 1457 32 - - SYM cord-005646-xhx9pzhj 1457 33 4.0 4.0 CD cord-005646-xhx9pzhj 1457 34 ) ) -RRB- cord-005646-xhx9pzhj 1457 35 kPa kPa NNS cord-005646-xhx9pzhj 1457 36 within within IN cord-005646-xhx9pzhj 1457 37 6 6 CD cord-005646-xhx9pzhj 1457 38 hours hour NNS cord-005646-xhx9pzhj 1457 39 . . . cord-005646-xhx9pzhj 1458 1 The the DT cord-005646-xhx9pzhj 1458 2 I i NN cord-005646-xhx9pzhj 1458 3 : : : cord-005646-xhx9pzhj 1458 4 E e NN cord-005646-xhx9pzhj 1458 5 ratio ratio NN cord-005646-xhx9pzhj 1458 6 also also RB cord-005646-xhx9pzhj 1458 7 significantly significantly RB cord-005646-xhx9pzhj 1458 8 decreased decrease VBD cord-005646-xhx9pzhj 1458 9 . . . cord-005646-xhx9pzhj 1459 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1459 2 : : : cord-005646-xhx9pzhj 1460 1 PSV PSV NNP cord-005646-xhx9pzhj 1460 2 permitted permit VBD cord-005646-xhx9pzhj 1460 3 patients patient NNS cord-005646-xhx9pzhj 1460 4 to to IN cord-005646-xhx9pzhj 1460 5 active active NNP cord-005646-xhx9pzhj 1460 6 / / SYM cord-005646-xhx9pzhj 1460 7 y y NN cord-005646-xhx9pzhj 1460 8 exhale exhale VBP cord-005646-xhx9pzhj 1460 9 while while IN cord-005646-xhx9pzhj 1460 10 unloading unload VBG cord-005646-xhx9pzhj 1460 11 the the DT cord-005646-xhx9pzhj 1460 12 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1460 13 work work NN cord-005646-xhx9pzhj 1460 14 of of IN cord-005646-xhx9pzhj 1460 15 breathing breathing NN cord-005646-xhx9pzhj 1460 16 . . . cord-005646-xhx9pzhj 1461 1 Perhaps perhaps RB cord-005646-xhx9pzhj 1461 2 this this DT cord-005646-xhx9pzhj 1461 3 strategy strategy NN cord-005646-xhx9pzhj 1461 4 shifts shift VBZ cord-005646-xhx9pzhj 1461 5 the the DT cord-005646-xhx9pzhj 1461 6 patient patient NN cord-005646-xhx9pzhj 1461 7 's 's POS cord-005646-xhx9pzhj 1461 8 respiratory respiratory JJ cord-005646-xhx9pzhj 1461 9 effort effort NN cord-005646-xhx9pzhj 1461 10 from from IN cord-005646-xhx9pzhj 1461 11 inspiration inspiration NN cord-005646-xhx9pzhj 1461 12 to to IN cord-005646-xhx9pzhj 1461 13 exhalation exhalation NN cord-005646-xhx9pzhj 1461 14 , , , cord-005646-xhx9pzhj 1461 15 thus thus RB cord-005646-xhx9pzhj 1461 16 permitting permit VBG cord-005646-xhx9pzhj 1461 17 the the DT cord-005646-xhx9pzhj 1461 18 child child NN cord-005646-xhx9pzhj 1461 19 to to TO cord-005646-xhx9pzhj 1461 20 meet meet VB cord-005646-xhx9pzhj 1461 21 the the DT cord-005646-xhx9pzhj 1461 22 excess excess JJ cord-005646-xhx9pzhj 1461 23 work work NN cord-005646-xhx9pzhj 1461 24 of of IN cord-005646-xhx9pzhj 1461 25 breathing breathing NN cord-005646-xhx9pzhj 1461 26 caused cause VBN cord-005646-xhx9pzhj 1461 27 by by IN cord-005646-xhx9pzhj 1461 28 bronchoconstriction bronchoconstriction NN cord-005646-xhx9pzhj 1461 29 . . . cord-005646-xhx9pzhj 1462 1 Maged Maged NNP cord-005646-xhx9pzhj 1462 2 Z. Z. NNP cord-005646-xhx9pzhj 1462 3 Youssef Youssef NNP cord-005646-xhx9pzhj 1462 4 , , , cord-005646-xhx9pzhj 1462 5 Peter Peter NNP cord-005646-xhx9pzhj 1462 6 Silver Silver NNP cord-005646-xhx9pzhj 1462 7 , , , cord-005646-xhx9pzhj 1462 8 Laura Laura NNP cord-005646-xhx9pzhj 1462 9 Nimkoff Nimkoff NNP cord-005646-xhx9pzhj 1462 10 , , , cord-005646-xhx9pzhj 1462 11 and and CC cord-005646-xhx9pzhj 1462 12 Mayer Mayer NNP cord-005646-xhx9pzhj 1462 13 Sagv Sagv NNP cord-005646-xhx9pzhj 1462 14 . . . cord-005646-xhx9pzhj 1463 1 Division division NN cord-005646-xhx9pzhj 1463 2 of of IN cord-005646-xhx9pzhj 1463 3 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1463 4 Critical Critical NNP cord-005646-xhx9pzhj 1463 5 Care Care NNP cord-005646-xhx9pzhj 1463 6 Medicine Medicine NNP cord-005646-xhx9pzhj 1463 7 , , , cord-005646-xhx9pzhj 1463 8 Schneider Schneider NNP cord-005646-xhx9pzhj 1463 9 Children Children NNP cord-005646-xhx9pzhj 1463 10 's 's POS cord-005646-xhx9pzhj 1463 11 Hospital Hospital NNP cord-005646-xhx9pzhj 1463 12 , , , cord-005646-xhx9pzhj 1463 13 New New NNP cord-005646-xhx9pzhj 1463 14 Hyde Hyde NNP cord-005646-xhx9pzhj 1463 15 Park Park NNP cord-005646-xhx9pzhj 1463 16 , , , cord-005646-xhx9pzhj 1463 17 NY NY NNP cord-005646-xhx9pzhj 1463 18 11040 11040 CD cord-005646-xhx9pzhj 1463 19 . . . cord-005646-xhx9pzhj 1464 1 Introduction introduction NN cord-005646-xhx9pzhj 1464 2 : : : cord-005646-xhx9pzhj 1465 1 Mechanical mechanical JJ cord-005646-xhx9pzhj 1465 2 vemiladon vemiladon NN cord-005646-xhx9pzhj 1465 3 of of IN cord-005646-xhx9pzhj 1465 4 patients patient NNS cord-005646-xhx9pzhj 1465 5 with with IN cord-005646-xhx9pzhj 1465 6 severe severe JJ cord-005646-xhx9pzhj 1465 7 bronchospasm bronchospasm NN cord-005646-xhx9pzhj 1465 8 can can MD cord-005646-xhx9pzhj 1465 9 be be VB cord-005646-xhx9pzhj 1465 10 difficult difficult JJ cord-005646-xhx9pzhj 1465 11 , , , cord-005646-xhx9pzhj 1465 12 due due IN cord-005646-xhx9pzhj 1465 13 to to IN cord-005646-xhx9pzhj 1465 14 poor poor JJ cord-005646-xhx9pzhj 1465 15 chest chest NN cord-005646-xhx9pzhj 1465 16 compliance compliance NN cord-005646-xhx9pzhj 1465 17 and and CC cord-005646-xhx9pzhj 1465 18 increased increase VBN cord-005646-xhx9pzhj 1465 19 airway airway NN cord-005646-xhx9pzhj 1465 20 resistance resistance NN cord-005646-xhx9pzhj 1465 21 . . . cord-005646-xhx9pzhj 1466 1 Ketarmne Ketarmne NNP cord-005646-xhx9pzhj 1466 2 is be VBZ cord-005646-xhx9pzhj 1466 3 a a DT cord-005646-xhx9pzhj 1466 4 cormnonly cormnonly RB cord-005646-xhx9pzhj 1466 5 used use VBN cord-005646-xhx9pzhj 1466 6 anesthetic anesthetic JJ cord-005646-xhx9pzhj 1466 7 agent agent NN cord-005646-xhx9pzhj 1466 8 that that WDT cord-005646-xhx9pzhj 1466 9 has have VBZ cord-005646-xhx9pzhj 1466 10 been be VBN cord-005646-xhx9pzhj 1466 11 shown show VBN cord-005646-xhx9pzhj 1466 12 to to TO cord-005646-xhx9pzhj 1466 13 have have VB cord-005646-xhx9pzhj 1466 14 bronchodilator bronchodilator NN cord-005646-xhx9pzhj 1466 15 properties property NNS cord-005646-xhx9pzhj 1466 16 . . . cord-005646-xhx9pzhj 1467 1 The the DT cord-005646-xhx9pzhj 1467 2 purpose purpose NN cord-005646-xhx9pzhj 1467 3 of of IN cord-005646-xhx9pzhj 1467 4 this this DT cord-005646-xhx9pzhj 1467 5 study study NN cord-005646-xhx9pzhj 1467 6 was be VBD cord-005646-xhx9pzhj 1467 7 to to TO cord-005646-xhx9pzhj 1467 8 determine determine VB cord-005646-xhx9pzhj 1467 9 ifa ifa NNP cord-005646-xhx9pzhj 1467 10 continuous continuous JJ cord-005646-xhx9pzhj 1467 11 infusion infusion NN cord-005646-xhx9pzhj 1467 12 of of IN cord-005646-xhx9pzhj 1467 13 ketamine ketamine NN cord-005646-xhx9pzhj 1467 14 had have VBD cord-005646-xhx9pzhj 1467 15 an an DT cord-005646-xhx9pzhj 1467 16 effect effect NN cord-005646-xhx9pzhj 1467 17 on on IN cord-005646-xhx9pzhj 1467 18 the the DT cord-005646-xhx9pzhj 1467 19 oxygenation oxygenation NN cord-005646-xhx9pzhj 1467 20 and and CC cord-005646-xhx9pzhj 1467 21 chest chest NN cord-005646-xhx9pzhj 1467 22 compliance compliance NN cord-005646-xhx9pzhj 1467 23 of of IN cord-005646-xhx9pzhj 1467 24 children child NNS cord-005646-xhx9pzhj 1467 25 with with IN cord-005646-xhx9pzhj 1467 26 severe severe JJ cord-005646-xhx9pzhj 1467 27 lironchospasm lironchospasm NN cord-005646-xhx9pzhj 1467 28 who who WP cord-005646-xhx9pzhj 1467 29 were be VBD cord-005646-xhx9pzhj 1467 30 mechanically mechanically RB cord-005646-xhx9pzhj 1467 31 ventilated ventilate VBN cord-005646-xhx9pzhj 1467 32 . . . cord-005646-xhx9pzhj 1468 1 Methods method NNS cord-005646-xhx9pzhj 1468 2 : : : cord-005646-xhx9pzhj 1469 1 A a DT cord-005646-xhx9pzhj 1469 2 retrospective retrospective JJ cord-005646-xhx9pzhj 1469 3 chart chart NN cord-005646-xhx9pzhj 1469 4 review review NN cord-005646-xhx9pzhj 1469 5 was be VBD cord-005646-xhx9pzhj 1469 6 conducted conduct VBN cord-005646-xhx9pzhj 1469 7 of of IN cord-005646-xhx9pzhj 1469 8 pediatric pediatric JJ cord-005646-xhx9pzhj 1469 9 patients patient NNS cord-005646-xhx9pzhj 1469 10 in in IN cord-005646-xhx9pzhj 1469 11 severe severe JJ cord-005646-xhx9pzhj 1469 12 bronchospasm bronchospasm NN cord-005646-xhx9pzhj 1469 13 who who WP cord-005646-xhx9pzhj 1469 14 were be VBD cord-005646-xhx9pzhj 1469 15 mechanically mechanically RB cord-005646-xhx9pzhj 1469 16 ventilated ventilate VBN cord-005646-xhx9pzhj 1469 17 in in IN cord-005646-xhx9pzhj 1469 18 our -PRON- PRP$ cord-005646-xhx9pzhj 1469 19 PICU PICU NNP cord-005646-xhx9pzhj 1469 20 and and CC cord-005646-xhx9pzhj 1469 21 treated treat VBN cord-005646-xhx9pzhj 1469 22 with with IN cord-005646-xhx9pzhj 1469 23 a a DT cord-005646-xhx9pzhj 1469 24 continuous continuous JJ cord-005646-xhx9pzhj 1469 25 ketamine ketamine NN cord-005646-xhx9pzhj 1469 26 infusion infusion NN cord-005646-xhx9pzhj 1469 27 . . . cord-005646-xhx9pzhj 1470 1 All all DT cord-005646-xhx9pzhj 1470 2 patients patient NNS cord-005646-xhx9pzhj 1470 3 were be VBD cord-005646-xhx9pzhj 1470 4 receiving receive VBG cord-005646-xhx9pzhj 1470 5 aggressive aggressive JJ cord-005646-xhx9pzhj 1470 6 bronchodilator bronchodilator NN cord-005646-xhx9pzhj 1470 7 therapy therapy NN cord-005646-xhx9pzhj 1470 8 and and CC cord-005646-xhx9pzhj 1470 9 adequate adequate JJ cord-005646-xhx9pzhj 1470 10 sedation sedation NN cord-005646-xhx9pzhj 1470 11 prior prior RB cord-005646-xhx9pzhj 1470 12 to to IN cord-005646-xhx9pzhj 1470 13 keramine keramine NNP cord-005646-xhx9pzhj 1470 14 . . . cord-005646-xhx9pzhj 1471 1 Patients patient NNS cord-005646-xhx9pzhj 1471 2 were be VBD cord-005646-xhx9pzhj 1471 3 excluded exclude VBN cord-005646-xhx9pzhj 1471 4 if if IN cord-005646-xhx9pzhj 1471 5 any any DT cord-005646-xhx9pzhj 1471 6 new new JJ cord-005646-xhx9pzhj 1471 7 bronchodilator bronchodilator NN cord-005646-xhx9pzhj 1471 8 or or CC cord-005646-xhx9pzhj 1471 9 sedative sedative JJ cord-005646-xhx9pzhj 1471 10 agents agent NNS cord-005646-xhx9pzhj 1471 11 were be VBD cord-005646-xhx9pzhj 1471 12 started start VBN cord-005646-xhx9pzhj 1471 13 within within IN cord-005646-xhx9pzhj 1471 14 24 24 CD cord-005646-xhx9pzhj 1471 15 hours hour NNS cord-005646-xhx9pzhj 1471 16 of of IN cord-005646-xhx9pzhj 1471 17 initiation initiation NN cord-005646-xhx9pzhj 1471 18 of of IN cord-005646-xhx9pzhj 1471 19 ketamine ketamine NN cord-005646-xhx9pzhj 1471 20 treatment treatment NN cord-005646-xhx9pzhj 1471 21 . . . cord-005646-xhx9pzhj 1472 1 All all DT cord-005646-xhx9pzhj 1472 2 patients patient NNS cord-005646-xhx9pzhj 1472 3 were be VBD cord-005646-xhx9pzhj 1472 4 simultaneously simultaneously RB cord-005646-xhx9pzhj 1472 5 treated treat VBN cord-005646-xhx9pzhj 1472 6 with with IN cord-005646-xhx9pzhj 1472 7 benzodiazepines benzodiazepine NNS cord-005646-xhx9pzhj 1472 8 . . . cord-005646-xhx9pzhj 1473 1 For for IN cord-005646-xhx9pzhj 1473 2 each each DT cord-005646-xhx9pzhj 1473 3 patient patient NN cord-005646-xhx9pzhj 1473 4 , , , cord-005646-xhx9pzhj 1473 5 the the DT cord-005646-xhx9pzhj 1473 6 PaO2 PaO2 NNPS cord-005646-xhx9pzhj 1473 7 / / SYM cord-005646-xhx9pzhj 1473 8 FiO FiO NNS cord-005646-xhx9pzhj 1473 9 ~ ~ CD cord-005646-xhx9pzhj 1473 10 ratio ratio NN cord-005646-xhx9pzhj 1473 11 and and CC cord-005646-xhx9pzhj 1473 12 dynamic dynamic JJ cord-005646-xhx9pzhj 1473 13 compliance compliance NN cord-005646-xhx9pzhj 1473 14 [ [ -LRB- cord-005646-xhx9pzhj 1473 15 tidal tidal JJ cord-005646-xhx9pzhj 1473 16 volume/(peak volume/(peak NNP cord-005646-xhx9pzhj 1473 17 imp imp NN cord-005646-xhx9pzhj 1473 18 . . . cord-005646-xhx9pzhj 1474 1 pressure pressure NN cord-005646-xhx9pzhj 1474 2 -PEEP -PEEP . cord-005646-xhx9pzhj 1474 3 ) ) -RRB- cord-005646-xhx9pzhj 1474 4 ] ] -RRB- cord-005646-xhx9pzhj 1474 5 was be VBD cord-005646-xhx9pzhj 1474 6 determined determine VBN cord-005646-xhx9pzhj 1474 7 immediately immediately RB cord-005646-xhx9pzhj 1474 8 prior prior RB cord-005646-xhx9pzhj 1474 9 to to IN cord-005646-xhx9pzhj 1474 10 ketamine ketamine NN cord-005646-xhx9pzhj 1474 11 , , , cord-005646-xhx9pzhj 1474 12 and and CC cord-005646-xhx9pzhj 1474 13 at at IN cord-005646-xhx9pzhj 1474 14 1 1 CD cord-005646-xhx9pzhj 1474 15 , , , cord-005646-xhx9pzhj 1474 16 8 8 CD cord-005646-xhx9pzhj 1474 17 , , , cord-005646-xhx9pzhj 1474 18 and and CC cord-005646-xhx9pzhj 1474 19 24 24 CD cord-005646-xhx9pzhj 1474 20 hours hour NNS cord-005646-xhx9pzhj 1474 21 post post VBP cord-005646-xhx9pzhj 1474 22 - - JJ cord-005646-xhx9pzhj 1474 23 ketsmine ketsmine JJ cord-005646-xhx9pzhj 1474 24 initiation initiation NN cord-005646-xhx9pzhj 1474 25 . . . cord-005646-xhx9pzhj 1475 1 Data datum NNS cord-005646-xhx9pzhj 1475 2 are be VBP cord-005646-xhx9pzhj 1475 3 presented present VBN cord-005646-xhx9pzhj 1475 4 as as IN cord-005646-xhx9pzhj 1475 5 mean mean NNP cord-005646-xhx9pzhj 1475 6 ± ± NNP cord-005646-xhx9pzhj 1475 7 S.D. S.D. NNP cord-005646-xhx9pzhj 1475 8 , , , cord-005646-xhx9pzhj 1475 9 and and CC cord-005646-xhx9pzhj 1475 10 were be VBD cord-005646-xhx9pzhj 1475 11 a~ a~ . cord-005646-xhx9pzhj 1476 1 yzed yzed NNP cord-005646-xhx9pzhj 1476 2 using use VBG cord-005646-xhx9pzhj 1476 3 one one CD cord-005646-xhx9pzhj 1476 4 way way NN cord-005646-xhx9pzhj 1476 5 ANOVA ANOVA NNP cord-005646-xhx9pzhj 1476 6 and and CC cord-005646-xhx9pzhj 1476 7 the the DT cord-005646-xhx9pzhj 1476 8 multiple multiple JJ cord-005646-xhx9pzhj 1476 9 comparison comparison NN cord-005646-xhx9pzhj 1476 10 method method NN cord-005646-xhx9pzhj 1476 11 of of IN cord-005646-xhx9pzhj 1476 12 Bonferroni Bonferroni NNP cord-005646-xhx9pzhj 1476 13 . . . cord-005646-xhx9pzhj 1477 1 patients patient NNS cord-005646-xhx9pzhj 1477 2 ( ( -LRB- cord-005646-xhx9pzhj 1477 3 age age NN cord-005646-xhx9pzhj 1477 4 6.0 6.0 CD cord-005646-xhx9pzhj 1477 5 ± ± CD cord-005646-xhx9pzhj 1477 6 5.7 5.7 CD cord-005646-xhx9pzhj 1477 7 yrs yr NNS cord-005646-xhx9pzhj 1477 8 . . . cord-005646-xhx9pzhj 1477 9 ) ) -RRB- cord-005646-xhx9pzhj 1477 10 received receive VBD cord-005646-xhx9pzhj 1477 11 * * NFP cord-005646-xhx9pzhj 1477 12 p<0.05 p<0.05 JJ cord-005646-xhx9pzhj 1477 13 ketamine ketamine NN cord-005646-xhx9pzhj 1477 14 for for IN cord-005646-xhx9pzhj 1477 15 severe severe JJ cord-005646-xhx9pzhj 1477 16 bronchospastu bronchospastu NNS cord-005646-xhx9pzhj 1477 17 during during IN cord-005646-xhx9pzhj 1477 18 mechanical mechanical JJ cord-005646-xhx9pzhj 1477 19 ventilation ventilation NN cord-005646-xhx9pzhj 1477 20 in in IN cord-005646-xhx9pzhj 1477 21 our -PRON- PRP$ cord-005646-xhx9pzhj 1477 22 PICU PICU NNP cord-005646-xhx9pzhj 1477 23 . . . cord-005646-xhx9pzhj 1478 1 Both both DT cord-005646-xhx9pzhj 1478 2 . . . cord-005646-xhx9pzhj 1479 1 .XTO- .XTO- NFP cord-005646-xhx9pzhj 1479 2 * * NFP cord-005646-xhx9pzhj 1479 3 * * NFP cord-005646-xhx9pzhj 1479 4 the the DT cord-005646-xhx9pzhj 1479 5 PaO2 PaO2 NNPS cord-005646-xhx9pzhj 1479 6 / / SYM cord-005646-xhx9pzhj 1479 7 FiO2 FiO2 NNS cord-005646-xhx9pzhj 1479 8 ratio ratio NN cord-005646-xhx9pzhj 1479 9 and and CC cord-005646-xhx9pzhj 1479 10 dynamic dynamic JJ cord-005646-xhx9pzhj 1479 11 . . . cord-005646-xhx9pzhj 1479 12 . . . cord-005646-xhx9pzhj 1480 1 - - : cord-005646-xhx9pzhj 1481 1 .... .... NFP cord-005646-xhx9pzhj 1481 2 . . . cord-005646-xhx9pzhj 1482 1 compliance compliance NN cord-005646-xhx9pzhj 1482 2 increased increase VBD cord-005646-xhx9pzhj 1482 3 significantly significantly RB cord-005646-xhx9pzhj 1482 4 following follow VBG cord-005646-xhx9pzhj 1482 5 initiation initiation NN cord-005646-xhx9pzhj 1482 6 of of IN cord-005646-xhx9pzhj 1482 7 the the DT cord-005646-xhx9pzhj 1482 8 ketamine ketamine NNP cord-005646-xhx9pzhj 1482 9 200infusion 200infusion NNP cord-005646-xhx9pzhj 1482 10 ( ( -LRB- cord-005646-xhx9pzhj 1482 11 see see VB cord-005646-xhx9pzhj 1482 12 figure figure NN cord-005646-xhx9pzhj 1482 13 ) ) -RRB- cord-005646-xhx9pzhj 1482 14 . . . cord-005646-xhx9pzhj 1483 1 The the DT cord-005646-xhx9pzhj 1483 2 mean mean JJ cord-005646-xhx9pzhj 1483 3 ketamine ketamine NN cord-005646-xhx9pzhj 1483 4 dose dose NN cord-005646-xhx9pzhj 1483 5 was be VBD cord-005646-xhx9pzhj 1483 6 32 32 CD cord-005646-xhx9pzhj 1483 7 ± ± NNP cord-005646-xhx9pzhj 1483 8 10 10 CD cord-005646-xhx9pzhj 1483 9 mcg mcg NNP cord-005646-xhx9pzhj 1483 10 / / SYM cord-005646-xhx9pzhj 1483 11 kg kg NNP cord-005646-xhx9pzhj 1483 12 / / SYM cord-005646-xhx9pzhj 1483 13 min min NNP cord-005646-xhx9pzhj 1483 14 , , , cord-005646-xhx9pzhj 1483 15 and and CC cord-005646-xhx9pzhj 1483 16 the the DT cord-005646-xhx9pzhj 1483 17 - - : cord-005646-xhx9pzhj 1483 18 , , , cord-005646-xhx9pzhj 1483 19 mean mean VB cord-005646-xhx9pzhj 1483 20 infusion infusion NN cord-005646-xhx9pzhj 1483 21 duration duration NN cord-005646-xhx9pzhj 1483 22 was be VBD cord-005646-xhx9pzhj 1483 23 40 40 CD cord-005646-xhx9pzhj 1483 24 ± ± NNP cord-005646-xhx9pzhj 1483 25 31 31 CD cord-005646-xhx9pzhj 1483 26 too-[/ too-[/ NNP cord-005646-xhx9pzhj 1483 27 hours hour NNS cord-005646-xhx9pzhj 1483 28 . . . cord-005646-xhx9pzhj 1484 1 One one CD cord-005646-xhx9pzhj 1484 2 patient patient NN cord-005646-xhx9pzhj 1484 3 required require VBD cord-005646-xhx9pzhj 1484 4 glycopyrrotate glycopyrrotate NNP cord-005646-xhx9pzhj 1484 5 6 6 CD cord-005646-xhx9pzhj 1484 6 ~ ~ NFP cord-005646-xhx9pzhj 1484 7 ' ' '' cord-005646-xhx9pzhj 1484 8 to to TO cord-005646-xhx9pzhj 1484 9 control control VB cord-005646-xhx9pzhj 1484 10 excessive excessive JJ cord-005646-xhx9pzhj 1484 11 airway airway NN cord-005646-xhx9pzhj 1484 12 secretions secretion NNS cord-005646-xhx9pzhj 1484 13 , , , cord-005646-xhx9pzhj 1484 14 and and CC cord-005646-xhx9pzhj 1484 15 " " `` cord-005646-xhx9pzhj 1484 16 one one CD cord-005646-xhx9pzhj 1484 17 patient patient NN cord-005646-xhx9pzhj 1484 18 required require VBD cord-005646-xhx9pzhj 1484 19 an an DT cord-005646-xhx9pzhj 1484 20 additional additional JJ cord-005646-xhx9pzhj 1484 21 dose dose NN cord-005646-xhx9pzhj 1484 22 of of IN cord-005646-xhx9pzhj 1484 23 O o NN cord-005646-xhx9pzhj 1484 24 -- -- : cord-005646-xhx9pzhj 1484 25 J J NNP cord-005646-xhx9pzhj 1484 26 I -PRON- PRP cord-005646-xhx9pzhj 1484 27 ~-~4 ~-~4 VBP cord-005646-xhx9pzhj 1485 1 ~/me ~/me NFP cord-005646-xhx9pzhj 1485 2 diazepam diazepam NN cord-005646-xhx9pzhj 1485 3 to to TO cord-005646-xhx9pzhj 1485 4 control control VB cord-005646-xhx9pzhj 1485 5 hallucinations hallucination NNS cord-005646-xhx9pzhj 1485 6 after after IN cord-005646-xhx9pzhj 1485 7 i i PRP cord-005646-xhx9pzhj 1485 8 8 8 CD cord-005646-xhx9pzhj 1485 9 cessation cessation NN cord-005646-xhx9pzhj 1485 10 of of IN cord-005646-xhx9pzhj 1485 11 ketamine ketamine NN cord-005646-xhx9pzhj 1485 12 . . . cord-005646-xhx9pzhj 1486 1 All all DT cord-005646-xhx9pzhj 1486 2 patients patient NNS cord-005646-xhx9pzhj 1486 3 were be VBD cord-005646-xhx9pzhj 1486 4 t~ t~ XX cord-005646-xhx9pzhj 1487 1 n~,mr~ n~,mr~ -LRB- cord-005646-xhx9pzhj 1488 1 * * NFP cord-005646-xhx9pzhj 1488 2 ~am~ ~am~ NFP cord-005646-xhx9pzhj 1488 3 successfully successfully RB cord-005646-xhx9pzhj 1488 4 weaned wean VBN cord-005646-xhx9pzhj 1488 5 off off RP cord-005646-xhx9pzhj 1488 6 mechanical mechanical JJ cord-005646-xhx9pzhj 1489 1 ~l ~l NNP cord-005646-xhx9pzhj 1490 1 ~s ~s NNP cord-005646-xhx9pzhj 1490 2 ~,~s ~,~s NFP cord-005646-xhx9pzhj 1490 3 ~ ~ NFP cord-005646-xhx9pzhj 1490 4 on on IN cord-005646-xhx9pzhj 1490 5 ventilation ventilation NN cord-005646-xhx9pzhj 1490 6 and and CC cord-005646-xhx9pzhj 1490 7 discharged discharge VBN cord-005646-xhx9pzhj 1490 8 from from IN cord-005646-xhx9pzhj 1490 9 the the DT cord-005646-xhx9pzhj 1490 10 PICU PICU NNP cord-005646-xhx9pzhj 1490 11 . . . cord-005646-xhx9pzhj 1491 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1491 2 : : : cord-005646-xhx9pzhj 1491 3 Continuous continuous JJ cord-005646-xhx9pzhj 1491 4 ketamine ketamine NN cord-005646-xhx9pzhj 1491 5 infusion infusion NN cord-005646-xhx9pzhj 1491 6 to to TO cord-005646-xhx9pzhj 1491 7 mechanically mechanically RB cord-005646-xhx9pzhj 1491 8 ventilated ventilate VBN cord-005646-xhx9pzhj 1491 9 pediatric pediatric JJ cord-005646-xhx9pzhj 1491 10 patients patient NNS cord-005646-xhx9pzhj 1491 11 with with IN cord-005646-xhx9pzhj 1491 12 refractory refractory JJ cord-005646-xhx9pzhj 1491 13 broncliospasm broncliospasm NN cord-005646-xhx9pzhj 1491 14 results result NNS cord-005646-xhx9pzhj 1491 15 in in IN cord-005646-xhx9pzhj 1491 16 a a DT cord-005646-xhx9pzhj 1491 17 significant significant JJ cord-005646-xhx9pzhj 1491 18 improvement improvement NN cord-005646-xhx9pzhj 1491 19 in in IN cord-005646-xhx9pzhj 1491 20 oxygenation oxygenation NN cord-005646-xhx9pzhj 1491 21 and and CC cord-005646-xhx9pzhj 1491 22 dynamic dynamic JJ cord-005646-xhx9pzhj 1491 23 compliance compliance NN cord-005646-xhx9pzhj 1491 24 of of IN cord-005646-xhx9pzhj 1491 25 the the DT cord-005646-xhx9pzhj 1491 26 chest chest NN cord-005646-xhx9pzhj 1491 27 . . . cord-005646-xhx9pzhj 1492 1 Reports report NNS cord-005646-xhx9pzhj 1492 2 of of IN cord-005646-xhx9pzhj 1492 3 adults adult NNS cord-005646-xhx9pzhj 1492 4 with with IN cord-005646-xhx9pzhj 1492 5 status status NN cord-005646-xhx9pzhj 1492 6 nsthraaticus nsthraaticus NNP cord-005646-xhx9pzhj 1492 7 document document NN cord-005646-xhx9pzhj 1492 8 significant significant JJ cord-005646-xhx9pzhj 1492 9 morbidity morbidity NN cord-005646-xhx9pzhj 1492 10 and and CC cord-005646-xhx9pzhj 1492 11 mortality mortality NN cord-005646-xhx9pzhj 1492 12 , , , cord-005646-xhx9pzhj 1492 13 whereas whereas IN cord-005646-xhx9pzhj 1492 14 studies study NNS cord-005646-xhx9pzhj 1492 15 in in IN cord-005646-xhx9pzhj 1492 16 children child NNS cord-005646-xhx9pzhj 1492 17 have have VBP cord-005646-xhx9pzhj 1492 18 had have VBN cord-005646-xhx9pzhj 1492 19 more more RBR cord-005646-xhx9pzhj 1492 20 varied varied JJ cord-005646-xhx9pzhj 1492 21 results result NNS cord-005646-xhx9pzhj 1492 22 . . . cord-005646-xhx9pzhj 1493 1 Different different JJ cord-005646-xhx9pzhj 1493 2 centers center NNS cord-005646-xhx9pzhj 1493 3 report report VBP cord-005646-xhx9pzhj 1493 4 mechanical mechanical JJ cord-005646-xhx9pzhj 1493 5 ventilation ventilation NN cord-005646-xhx9pzhj 1493 6 ( ( -LRB- cord-005646-xhx9pzhj 1493 7 MV MV NNP cord-005646-xhx9pzhj 1493 8 ) ) -RRB- cord-005646-xhx9pzhj 1493 9 in in IN cord-005646-xhx9pzhj 1493 10 10 10 CD cord-005646-xhx9pzhj 1493 11 to to TO cord-005646-xhx9pzhj 1493 12 33 33 CD cord-005646-xhx9pzhj 1493 13 % % NN cord-005646-xhx9pzhj 1493 14 of of IN cord-005646-xhx9pzhj 1493 15 admissions admission NNS cord-005646-xhx9pzhj 1493 16 , , , cord-005646-xhx9pzhj 1493 17 occurrence occurrence NN cord-005646-xhx9pzhj 1493 18 of of IN cord-005646-xhx9pzhj 1493 19 pneumothoraces pneumothorace NNS cord-005646-xhx9pzhj 1493 20 or or CC cord-005646-xhx9pzhj 1493 21 paeutuomediastinums paeutuomediastinum NNS cord-005646-xhx9pzhj 1493 22 in in IN cord-005646-xhx9pzhj 1493 23 2 2 CD cord-005646-xhx9pzhj 1493 24 to to TO cord-005646-xhx9pzhj 1493 25 11 11 CD cord-005646-xhx9pzhj 1493 26 % % NN cord-005646-xhx9pzhj 1493 27 , , , cord-005646-xhx9pzhj 1493 28 and and CC cord-005646-xhx9pzhj 1493 29 mortality mortality NN cord-005646-xhx9pzhj 1493 30 in in IN cord-005646-xhx9pzhj 1493 31 up up IN cord-005646-xhx9pzhj 1493 32 to to TO cord-005646-xhx9pzhj 1493 33 7 7 CD cord-005646-xhx9pzhj 1493 34 % % NN cord-005646-xhx9pzhj 1493 35 of of IN cord-005646-xhx9pzhj 1493 36 patients patient NNS cord-005646-xhx9pzhj 1493 37 ~'t3 ~'t3 ADD cord-005646-xhx9pzhj 1493 38 . . . cord-005646-xhx9pzhj 1494 1 We -PRON- PRP cord-005646-xhx9pzhj 1494 2 retrospectively retrospectively RB cord-005646-xhx9pzhj 1494 3 reviewed review VBD cord-005646-xhx9pzhj 1494 4 113 113 CD cord-005646-xhx9pzhj 1494 5 status status NN cord-005646-xhx9pzhj 1494 6 asthmaticus asthmaticus NNP cord-005646-xhx9pzhj 1494 7 admissions admission NNS cord-005646-xhx9pzhj 1494 8 to to IN cord-005646-xhx9pzhj 1494 9 the the DT cord-005646-xhx9pzhj 1494 10 pediatric pediatric JJ cord-005646-xhx9pzhj 1494 11 intensive intensive JJ cord-005646-xhx9pzhj 1494 12 care care NN cord-005646-xhx9pzhj 1494 13 unit unit NN cord-005646-xhx9pzhj 1494 14 ( ( -LRB- cord-005646-xhx9pzhj 1494 15 PICU PICU NNP cord-005646-xhx9pzhj 1494 16 ) ) -RRB- cord-005646-xhx9pzhj 1494 17 between between IN cord-005646-xhx9pzhj 1494 18 January January NNP cord-005646-xhx9pzhj 1494 19 1993 1993 CD cord-005646-xhx9pzhj 1494 20 and and CC cord-005646-xhx9pzhj 1494 21 December December NNP cord-005646-xhx9pzhj 1494 22 1995 1995 CD cord-005646-xhx9pzhj 1494 23 . . . cord-005646-xhx9pzhj 1495 1 Seventy seventy CD cord-005646-xhx9pzhj 1495 2 - - HYPH cord-005646-xhx9pzhj 1495 3 five five CD cord-005646-xhx9pzhj 1495 4 of of IN cord-005646-xhx9pzhj 1495 5 these these DT cord-005646-xhx9pzhj 1495 6 patients patient NNS cord-005646-xhx9pzhj 1495 7 were be VBD cord-005646-xhx9pzhj 1495 8 admitted admit VBN cord-005646-xhx9pzhj 1495 9 fr fr IN cord-005646-xhx9pzhj 1495 10 ~ ~ NNP cord-005646-xhx9pzhj 1495 11 an an DT cord-005646-xhx9pzhj 1495 12 the the DT cord-005646-xhx9pzhj 1495 13 emergency emergency NN cord-005646-xhx9pzhj 1495 14 department department NN cord-005646-xhx9pzhj 1495 15 of of IN cord-005646-xhx9pzhj 1495 16 CHLA CHLA NNP cord-005646-xhx9pzhj 1495 17 ( ( -LRB- cord-005646-xhx9pzhj 1495 18 ER ER NNP cord-005646-xhx9pzhj 1495 19 Admit Admit NNP cord-005646-xhx9pzhj 1495 20 ) ) -RRB- cord-005646-xhx9pzhj 1495 21 . . . cord-005646-xhx9pzhj 1496 1 The the DT cord-005646-xhx9pzhj 1496 2 mean mean JJ cord-005646-xhx9pzhj 1496 3 length length NN cord-005646-xhx9pzhj 1496 4 of of IN cord-005646-xhx9pzhj 1496 5 stay stay NN cord-005646-xhx9pzhj 1496 6 in in IN cord-005646-xhx9pzhj 1496 7 the the DT cord-005646-xhx9pzhj 1496 8 PICU PICU NNP cord-005646-xhx9pzhj 1496 9 was be VBD cord-005646-xhx9pzhj 1496 10 2.1 2.1 CD cord-005646-xhx9pzhj 1496 11 days day NNS cord-005646-xhx9pzhj 1496 12 and and CC cord-005646-xhx9pzhj 1496 13 the the DT cord-005646-xhx9pzhj 1496 14 mean mean JJ cord-005646-xhx9pzhj 1496 15 length length NN cord-005646-xhx9pzhj 1496 16 of of IN cord-005646-xhx9pzhj 1496 17 stay stay NN cord-005646-xhx9pzhj 1496 18 in in IN cord-005646-xhx9pzhj 1496 19 the the DT cord-005646-xhx9pzhj 1496 20 hospital hospital NN cord-005646-xhx9pzhj 1496 21 was be VBD cord-005646-xhx9pzhj 1496 22 4.6 4.6 CD cord-005646-xhx9pzhj 1496 23 days day NNS cord-005646-xhx9pzhj 1496 24 . . . cord-005646-xhx9pzhj 1497 1 Based base VBN cord-005646-xhx9pzhj 1497 2 on on IN cord-005646-xhx9pzhj 1497 3 95 95 CD cord-005646-xhx9pzhj 1497 4 patients patient NNS cord-005646-xhx9pzhj 1497 5 who who WP cord-005646-xhx9pzhj 1497 6 had have VBD cord-005646-xhx9pzhj 1497 7 arterial arterial JJ cord-005646-xhx9pzhj 1497 8 blood blood NN cord-005646-xhx9pzhj 1497 9 analyses analysis NNS cord-005646-xhx9pzhj 1497 10 , , , cord-005646-xhx9pzhj 1497 11 36 36 CD cord-005646-xhx9pzhj 1497 12 patients patient NNS cord-005646-xhx9pzhj 1497 13 had have VBD cord-005646-xhx9pzhj 1497 14 hyperoapnia hyperoapnia VBN cord-005646-xhx9pzhj 1497 15 ( ( -LRB- cord-005646-xhx9pzhj 1497 16 pCO2 pCO2 NNP cord-005646-xhx9pzhj 1497 17 > > XX cord-005646-xhx9pzhj 1497 18 45 45 CD cord-005646-xhx9pzhj 1497 19 ) ) -RRB- cord-005646-xhx9pzhj 1497 20 . . . cord-005646-xhx9pzhj 1498 1 All all DT cord-005646-xhx9pzhj 1498 2 patients patient NNS cord-005646-xhx9pzhj 1498 3 received receive VBD cord-005646-xhx9pzhj 1498 4 oxygen oxygen NN cord-005646-xhx9pzhj 1498 5 , , , cord-005646-xhx9pzhj 1498 6 inhaled inhale VBN cord-005646-xhx9pzhj 1498 7 albuterol albuterol NN cord-005646-xhx9pzhj 1498 8 ( ( -LRB- cord-005646-xhx9pzhj 1498 9 Alb Alb NNP cord-005646-xhx9pzhj 1498 10 ) ) -RRB- cord-005646-xhx9pzhj 1498 11 , , , cord-005646-xhx9pzhj 1498 12 and and CC cord-005646-xhx9pzhj 1498 13 cortieosteroid cortieosteroid NNP cord-005646-xhx9pzhj 1498 14 therapy therapy NN cord-005646-xhx9pzhj 1498 15 . . . cord-005646-xhx9pzhj 1499 1 Ninety ninety CD cord-005646-xhx9pzhj 1499 2 - - HYPH cord-005646-xhx9pzhj 1499 3 five five CD cord-005646-xhx9pzhj 1499 4 percent percent NN cord-005646-xhx9pzhj 1499 5 of of IN cord-005646-xhx9pzhj 1499 6 patients patient NNS cord-005646-xhx9pzhj 1499 7 also also RB cord-005646-xhx9pzhj 1499 8 received receive VBD cord-005646-xhx9pzhj 1499 9 methylxanthine methylxanthine NN cord-005646-xhx9pzhj 1499 10 ( ( -LRB- cord-005646-xhx9pzhj 1499 11 MX MX NNP cord-005646-xhx9pzhj 1499 12 ) ) -RRB- cord-005646-xhx9pzhj 1499 13 therapy therapy NN cord-005646-xhx9pzhj 1499 14 . . . cord-005646-xhx9pzhj 1500 1 Of of IN cord-005646-xhx9pzhj 1500 2 the the DT cord-005646-xhx9pzhj 1500 3 113 113 CD cord-005646-xhx9pzhj 1500 4 admissions admission NNS cord-005646-xhx9pzhj 1500 5 , , , cord-005646-xhx9pzhj 1500 6 12 12 CD cord-005646-xhx9pzhj 1500 7 patients patient NNS cord-005646-xhx9pzhj 1500 8 ( ( -LRB- cord-005646-xhx9pzhj 1500 9 11 11 CD cord-005646-xhx9pzhj 1500 10 % % NN cord-005646-xhx9pzhj 1500 11 ) ) -RRB- cord-005646-xhx9pzhj 1500 12 required require VBD cord-005646-xhx9pzhj 1500 13 MV MV NNP cord-005646-xhx9pzhj 1500 14 . . . cord-005646-xhx9pzhj 1501 1 Only only RB cord-005646-xhx9pzhj 1501 2 4 4 CD cord-005646-xhx9pzhj 1501 3 of of IN cord-005646-xhx9pzhj 1501 4 these these DT cord-005646-xhx9pzhj 1501 5 patients patient NNS cord-005646-xhx9pzhj 1501 6 were be VBD cord-005646-xhx9pzhj 1501 7 admitted admit VBN cord-005646-xhx9pzhj 1501 8 through through IN cord-005646-xhx9pzhj 1501 9 our -PRON- PRP$ cord-005646-xhx9pzhj 1501 10 emergency emergency NN cord-005646-xhx9pzhj 1501 11 department department NN cord-005646-xhx9pzhj 1501 12 , , , cord-005646-xhx9pzhj 1501 13 whereas whereas IN cord-005646-xhx9pzhj 1501 14 the the DT cord-005646-xhx9pzhj 1501 15 remaining remain VBG cord-005646-xhx9pzhj 1501 16 8 8 CD cord-005646-xhx9pzhj 1501 17 patients patient NNS cord-005646-xhx9pzhj 1501 18 were be VBD cord-005646-xhx9pzhj 1501 19 intuhated intuhate VBN cord-005646-xhx9pzhj 1501 20 at at IN cord-005646-xhx9pzhj 1501 21 outside outside JJ cord-005646-xhx9pzhj 1501 22 facilities facility NNS cord-005646-xhx9pzhj 1501 23 . . . cord-005646-xhx9pzhj 1502 1 Twenty twenty CD cord-005646-xhx9pzhj 1502 2 - - HYPH cord-005646-xhx9pzhj 1502 3 three three CD cord-005646-xhx9pzhj 1502 4 cases case NNS cord-005646-xhx9pzhj 1502 5 required require VBN cord-005646-xhx9pzhj 1502 6 intr intr NN cord-005646-xhx9pzhj 1502 7 : : : cord-005646-xhx9pzhj 1502 8 wenous wenous JJ cord-005646-xhx9pzhj 1502 9 beta beta NN cord-005646-xhx9pzhj 1502 10 - - HYPH cord-005646-xhx9pzhj 1502 11 agonist agonist NN cord-005646-xhx9pzhj 1502 12 therapy therapy NN cord-005646-xhx9pzhj 1502 13 , , , cord-005646-xhx9pzhj 1502 14 either either CC cord-005646-xhx9pzhj 1502 15 isoproterenol isoproterenol NNP cord-005646-xhx9pzhj 1502 16 Osop Osop NNP cord-005646-xhx9pzhj 1502 17 ) ) -RRB- cord-005646-xhx9pzhj 1502 18 or or CC cord-005646-xhx9pzhj 1502 19 terbutaline terbutaline NN cord-005646-xhx9pzhj 1502 20 ( ( -LRB- cord-005646-xhx9pzhj 1502 21 Terb Terb NNP cord-005646-xhx9pzhj 1502 22 ) ) -RRB- cord-005646-xhx9pzhj 1502 23 . . . cord-005646-xhx9pzhj 1503 1 H H NNP cord-005646-xhx9pzhj 1503 2 ~ ~ CD cord-005646-xhx9pzhj 1503 3 ff ff NN cord-005646-xhx9pzhj 1503 4 of of IN cord-005646-xhx9pzhj 1503 5 the the DT cord-005646-xhx9pzhj 1503 6 ea.~es ea.~es NNP cord-005646-xhx9pzhj 1503 7 re~%wed re~%wed CD cord-005646-xhx9pzhj 1503 8 were be VBD cord-005646-xhx9pzhj 1503 9 complicated complicate VBN cord-005646-xhx9pzhj 1503 10 with with IN cord-005646-xhx9pzhj 1503 11 hypokalemia hypokalemia NN cord-005646-xhx9pzhj 1503 12 ( ( -LRB- cord-005646-xhx9pzhj 1503 13 K+ K+ NNP cord-005646-xhx9pzhj 1503 14 < < XX cord-005646-xhx9pzhj 1503 15 3.5 3.5 CD cord-005646-xhx9pzhj 1503 16 ) ) -RRB- cord-005646-xhx9pzhj 1503 17 . . . cord-005646-xhx9pzhj 1504 1 C C NNP cord-005646-xhx9pzhj 1504 2 , , , cord-005646-xhx9pzhj 1504 3 ' ' '' cord-005646-xhx9pzhj 1504 4 , , , cord-005646-xhx9pzhj 1504 5 , , , cord-005646-xhx9pzhj 1504 6 ~lications ~lications NNP cord-005646-xhx9pzhj 1504 7 ofpoeumothoraces ofpoeumothorace NNS cord-005646-xhx9pzhj 1504 8 or or CC cord-005646-xhx9pzhj 1504 9 pneumomediastinums pneumomediastinum NNS cord-005646-xhx9pzhj 1504 10 were be VBD cord-005646-xhx9pzhj 1504 11 seen see VBN cord-005646-xhx9pzhj 1504 12 in in IN cord-005646-xhx9pzhj 1504 13 10 10 CD cord-005646-xhx9pzhj 1504 14 % % NN cord-005646-xhx9pzhj 1504 15 of of IN cord-005646-xhx9pzhj 1504 16 , , , cord-005646-xhx9pzhj 1504 17 ' ' '' cord-005646-xhx9pzhj 1504 18 r r NN cord-005646-xhx9pzhj 1504 19 : : : cord-005646-xhx9pzhj 1504 20 u u LS cord-005646-xhx9pzhj 1504 21 ~ ~ CD cord-005646-xhx9pzhj 1504 22 ported port VBD cord-005646-xhx9pzhj 1504 23 patients patient NNS cord-005646-xhx9pzhj 1504 24 , , , cord-005646-xhx9pzhj 1504 25 but but CC cord-005646-xhx9pzhj 1504 26 in in IN cord-005646-xhx9pzhj 1504 27 only only RB cord-005646-xhx9pzhj 1504 28 4 4 CD cord-005646-xhx9pzhj 1504 29 % % NN cord-005646-xhx9pzhj 1504 30 of of IN cord-005646-xhx9pzhj 1504 31 ER ER NNP cord-005646-xhx9pzhj 1504 32 Admit admit VBP cord-005646-xhx9pzhj 1504 33 patients patient NNS cord-005646-xhx9pzhj 1504 34 . . . cord-005646-xhx9pzhj 1505 1 Only only RB cord-005646-xhx9pzhj 1505 2 2 2 CD cord-005646-xhx9pzhj 1505 3 % % NN cord-005646-xhx9pzhj 1505 4 of of IN cord-005646-xhx9pzhj 1505 5 these these DT cord-005646-xhx9pzhj 1505 6 were be VBD cord-005646-xhx9pzhj 1505 7 in in IN cord-005646-xhx9pzhj 1505 8 mechanic.all mechanic.all ADD cord-005646-xhx9pzhj 1505 9 , , , cord-005646-xhx9pzhj 1505 10 ) ) -RRB- cord-005646-xhx9pzhj 1505 11 atients atient NNS cord-005646-xhx9pzhj 1505 12 . . . cord-005646-xhx9pzhj 1506 1 There there EX cord-005646-xhx9pzhj 1506 2 were be VBD cord-005646-xhx9pzhj 1506 3 no no DT cord-005646-xhx9pzhj 1506 4 deaths death NNS cord-005646-xhx9pzhj 1506 5 in in IN cord-005646-xhx9pzhj 1506 6 the the DT cord-005646-xhx9pzhj 1506 7 review review NN cord-005646-xhx9pzhj 1506 8 . . . cord-005646-xhx9pzhj 1507 1 Respiratory respiratory JJ cord-005646-xhx9pzhj 1507 2 mechanics mechanic NNS cord-005646-xhx9pzhj 1507 3 measurements measurement NNS cord-005646-xhx9pzhj 1507 4 ' ' '' cord-005646-xhx9pzhj 1507 5 are be VBP cord-005646-xhx9pzhj 1507 6 useful useful JJ cord-005646-xhx9pzhj 1507 7 in in IN cord-005646-xhx9pzhj 1507 8 mechanically mechanically RB cord-005646-xhx9pzhj 1507 9 ventilated ventilate VBN cord-005646-xhx9pzhj 1507 10 children child NNS cord-005646-xhx9pzhj 1507 11 to to TO cord-005646-xhx9pzhj 1507 12 optimize optimize VB cord-005646-xhx9pzhj 1507 13 ventilator ventilator NN cord-005646-xhx9pzhj 1507 14 settings setting NNS cord-005646-xhx9pzhj 1507 15 . . . cord-005646-xhx9pzhj 1508 1 Nevertheless nevertheless RB cord-005646-xhx9pzhj 1508 2 , , , cord-005646-xhx9pzhj 1508 3 the the DT cord-005646-xhx9pzhj 1508 4 transducers transducer NNS cord-005646-xhx9pzhj 1508 5 used use VBD cord-005646-xhx9pzhj 1508 6 to to TO cord-005646-xhx9pzhj 1508 7 measure measure VB cord-005646-xhx9pzhj 1508 8 flow flow NN cord-005646-xhx9pzhj 1508 9 ( ( -LRB- cord-005646-xhx9pzhj 1508 10 F F NNP cord-005646-xhx9pzhj 1508 11 ) ) -RRB- cord-005646-xhx9pzhj 1508 12 and and CC cord-005646-xhx9pzhj 1508 13 pressure pressure NN cord-005646-xhx9pzhj 1508 14 ( ( -LRB- cord-005646-xhx9pzhj 1508 15 P p NN cord-005646-xhx9pzhj 1508 16 ) ) -RRB- cord-005646-xhx9pzhj 1508 17 remain remain VBP cord-005646-xhx9pzhj 1508 18 expensive expensive JJ cord-005646-xhx9pzhj 1508 19 . . . cord-005646-xhx9pzhj 1509 1 Objective objective JJ cord-005646-xhx9pzhj 1509 2 . . . cord-005646-xhx9pzhj 1510 1 To to TO cord-005646-xhx9pzhj 1510 2 evaluate evaluate VB cord-005646-xhx9pzhj 1510 3 the the DT cord-005646-xhx9pzhj 1510 4 performances performance NNS cord-005646-xhx9pzhj 1510 5 of of IN cord-005646-xhx9pzhj 1510 6 piezoelectric piezoelectric JJ cord-005646-xhx9pzhj 1510 7 P p NN cord-005646-xhx9pzhj 1510 8 transducers transducer NNS cord-005646-xhx9pzhj 1510 9 ( ( -LRB- cord-005646-xhx9pzhj 1510 10 350 350 CD cord-005646-xhx9pzhj 1510 11 US US NNP cord-005646-xhx9pzhj 1510 12 Dollar Dollar NNP cord-005646-xhx9pzhj 1510 13 ) ) -RRB- cord-005646-xhx9pzhj 1510 14 in in IN cord-005646-xhx9pzhj 1510 15 measuring measure VBG cord-005646-xhx9pzhj 1510 16 F F NNP cord-005646-xhx9pzhj 1510 17 and and CC cord-005646-xhx9pzhj 1510 18 P. P. NNP cord-005646-xhx9pzhj 1510 19 Methods Methods NNPS cord-005646-xhx9pzhj 1510 20 . . . cord-005646-xhx9pzhj 1511 1 We -PRON- PRP cord-005646-xhx9pzhj 1511 2 used use VBD cord-005646-xhx9pzhj 1511 3 a a DT cord-005646-xhx9pzhj 1511 4 previously previously RB cord-005646-xhx9pzhj 1511 5 described describe VBN cord-005646-xhx9pzhj 1511 6 monitoring monitoring NN cord-005646-xhx9pzhj 1511 7 system system NN cord-005646-xhx9pzhj 1511 8 measuring measure VBG cord-005646-xhx9pzhj 1511 9 respiratory respiratory JJ cord-005646-xhx9pzhj 1511 10 parameters parameter NNS cord-005646-xhx9pzhj 1511 11 [ [ -LRB- cord-005646-xhx9pzhj 1511 12 1 1 CD cord-005646-xhx9pzhj 1511 13 ] ] -RRB- cord-005646-xhx9pzhj 1511 14 . . . cord-005646-xhx9pzhj 1512 1 In in IN cord-005646-xhx9pzhj 1512 2 this this DT cord-005646-xhx9pzhj 1512 3 study study NN cord-005646-xhx9pzhj 1512 4 F F NNP cord-005646-xhx9pzhj 1512 5 was be VBD cord-005646-xhx9pzhj 1512 6 obtained obtain VBN cord-005646-xhx9pzhj 1512 7 by by IN cord-005646-xhx9pzhj 1512 8 a a DT cord-005646-xhx9pzhj 1512 9 differential differential JJ cord-005646-xhx9pzhj 1512 10 piezoelectric piezoelectric NN cord-005646-xhx9pzhj 1512 11 P p NN cord-005646-xhx9pzhj 1512 12 transducer transducer NN cord-005646-xhx9pzhj 1512 13 ( ( -LRB- cord-005646-xhx9pzhj 1512 14 _ _ NN cord-005646-xhx9pzhj 1512 15 + + SYM cord-005646-xhx9pzhj 1512 16 12.7 12.7 CD cord-005646-xhx9pzhj 1512 17 cmI cmI NNS cord-005646-xhx9pzhj 1512 18 - - : cord-005646-xhx9pzhj 1512 19 I20 I20 NNP cord-005646-xhx9pzhj 1512 20 , , , cord-005646-xhx9pzhj 1512 21 Honeywell Honeywell NNP cord-005646-xhx9pzhj 1512 22 ) ) -RRB- cord-005646-xhx9pzhj 1512 23 whose whose WP$ cord-005646-xhx9pzhj 1512 24 sensitivity sensitivity NN cord-005646-xhx9pzhj 1512 25 has have VBZ cord-005646-xhx9pzhj 1512 26 been be VBN cord-005646-xhx9pzhj 1512 27 reduced reduce VBN cord-005646-xhx9pzhj 1512 28 to to IN cord-005646-xhx9pzhj 1512 29 + + CC cord-005646-xhx9pzhj 1512 30 _ _ NN cord-005646-xhx9pzhj 1512 31 2 2 CD cord-005646-xhx9pzhj 1512 32 cmH20 cmH20 NNP cord-005646-xhx9pzhj 1512 33 by by IN cord-005646-xhx9pzhj 1512 34 an an DT cord-005646-xhx9pzhj 1512 35 electronic electronic JJ cord-005646-xhx9pzhj 1512 36 amplification amplification NN cord-005646-xhx9pzhj 1512 37 equipment equipment NN cord-005646-xhx9pzhj 1512 38 and and CC cord-005646-xhx9pzhj 1512 39 P p NN cord-005646-xhx9pzhj 1512 40 by by IN cord-005646-xhx9pzhj 1512 41 a a DT cord-005646-xhx9pzhj 1512 42 piezoelectric piezoelectric JJ cord-005646-xhx9pzhj 1512 43 P p NN cord-005646-xhx9pzhj 1512 44 transducer transducer NN cord-005646-xhx9pzhj 1512 45 ( ( -LRB- cord-005646-xhx9pzhj 1512 46 _ _ NN cord-005646-xhx9pzhj 1512 47 + + CC cord-005646-xhx9pzhj 1512 48 7().3 7().3 NNP cord-005646-xhx9pzhj 1512 49 cmHzO cmHzO NNP cord-005646-xhx9pzhj 1512 50 , , , cord-005646-xhx9pzhj 1512 51 Honeywell Honeywell NNP cord-005646-xhx9pzhj 1512 52 ) ) -RRB- cord-005646-xhx9pzhj 1512 53 connected connect VBD cord-005646-xhx9pzhj 1512 54 to to IN cord-005646-xhx9pzhj 1512 55 a a DT cord-005646-xhx9pzhj 1512 56 grid grid NN cord-005646-xhx9pzhj 1512 57 pneumotachymeter pneumotachymeter NN cord-005646-xhx9pzhj 1512 58 & & CC cord-005646-xhx9pzhj 1512 59 NT NT NNP cord-005646-xhx9pzhj 1512 60 ) ) -RRB- cord-005646-xhx9pzhj 1512 61 ffleisch ffleisch JJ cord-005646-xhx9pzhj 1512 62 0 0 CD cord-005646-xhx9pzhj 1512 63 or or CC cord-005646-xhx9pzhj 1512 64 1 1 CD cord-005646-xhx9pzhj 1512 65 ) ) -RRB- cord-005646-xhx9pzhj 1512 66 . . . cord-005646-xhx9pzhj 1513 1 Volume volume NN cord-005646-xhx9pzhj 1513 2 ( ( -LRB- cord-005646-xhx9pzhj 1513 3 V v NN cord-005646-xhx9pzhj 1513 4 ) ) -RRB- cord-005646-xhx9pzhj 1513 5 ( ( -LRB- cord-005646-xhx9pzhj 1513 6 5 5 CD cord-005646-xhx9pzhj 1513 7 to to TO cord-005646-xhx9pzhj 1513 8 400 400 CD cord-005646-xhx9pzhj 1513 9 ml ml NNS cord-005646-xhx9pzhj 1513 10 ) ) -RRB- cord-005646-xhx9pzhj 1513 11 obtained obtain VBN cord-005646-xhx9pzhj 1513 12 by by IN cord-005646-xhx9pzhj 1513 13 numeric numeric JJ cord-005646-xhx9pzhj 1513 14 integration integration NN cord-005646-xhx9pzhj 1513 15 ofF ofF NNS cord-005646-xhx9pzhj 1513 16 ( ( -LRB- cord-005646-xhx9pzhj 1513 17 0.125 0.125 CD cord-005646-xhx9pzhj 1513 18 to to IN cord-005646-xhx9pzhj 1513 19 10 10 CD cord-005646-xhx9pzhj 1513 20 L l NN cord-005646-xhx9pzhj 1513 21 / / SYM cord-005646-xhx9pzhj 1513 22 rnin rnin NN cord-005646-xhx9pzhj 1513 23 ) ) -RRB- cord-005646-xhx9pzhj 1513 24 and and CC cord-005646-xhx9pzhj 1514 1 P p NN cord-005646-xhx9pzhj 1514 2 ( ( -LRB- cord-005646-xhx9pzhj 1514 3 2 2 CD cord-005646-xhx9pzhj 1514 4 to to IN cord-005646-xhx9pzhj 1514 5 70 70 CD cord-005646-xhx9pzhj 1514 6 cmH20 cmh20 CD cord-005646-xhx9pzhj 1514 7 ) ) -RRB- cord-005646-xhx9pzhj 1514 8 were be VBD cord-005646-xhx9pzhj 1514 9 respectively respectively RB cord-005646-xhx9pzhj 1514 10 delivered deliver VBN cord-005646-xhx9pzhj 1514 11 through through IN cord-005646-xhx9pzhj 1514 12 a a DT cord-005646-xhx9pzhj 1514 13 calibrated calibrate VBN cord-005646-xhx9pzhj 1514 14 seringe seringe NN cord-005646-xhx9pzhj 1514 15 and and CC cord-005646-xhx9pzhj 1514 16 an an DT cord-005646-xhx9pzhj 1514 17 electronical electronical JJ cord-005646-xhx9pzhj 1514 18 manometer manometer NN cord-005646-xhx9pzhj 1514 19 ( ( -LRB- cord-005646-xhx9pzhj 1514 20 Pic pic NN cord-005646-xhx9pzhj 1514 21 400 400 CD cord-005646-xhx9pzhj 1514 22 Premier Premier NNP cord-005646-xhx9pzhj 1514 23 ) ) -RRB- cord-005646-xhx9pzhj 1514 24 and and CC cord-005646-xhx9pzhj 1514 25 calculated calculate VBN cord-005646-xhx9pzhj 1514 26 by by IN cord-005646-xhx9pzhj 1514 27 the the DT cord-005646-xhx9pzhj 1514 28 computer computer NN cord-005646-xhx9pzhj 1514 29 . . . cord-005646-xhx9pzhj 1515 1 Bland Bland NNP cord-005646-xhx9pzhj 1515 2 and and CC cord-005646-xhx9pzhj 1515 3 Altman Altman NNP cord-005646-xhx9pzhj 1515 4 analysis analysis NN cord-005646-xhx9pzhj 1515 5 was be VBD cord-005646-xhx9pzhj 1515 6 used use VBN cord-005646-xhx9pzhj 1515 7 for for IN cord-005646-xhx9pzhj 1515 8 assessment assessment NN cord-005646-xhx9pzhj 1515 9 of of IN cord-005646-xhx9pzhj 1515 10 results result NNS cord-005646-xhx9pzhj 1515 11 bias bias NN cord-005646-xhx9pzhj 1515 12 . . . cord-005646-xhx9pzhj 1516 1 Coefficient coefficient NN cord-005646-xhx9pzhj 1516 2 of of IN cord-005646-xhx9pzhj 1516 3 repeatability repeatability NN cord-005646-xhx9pzhj 1516 4 ( ( -LRB- cord-005646-xhx9pzhj 1516 5 CR CR NNP cord-005646-xhx9pzhj 1516 6 ) ) -RRB- cord-005646-xhx9pzhj 1516 7 was be VBD cord-005646-xhx9pzhj 1516 8 estimated estimate VBN cord-005646-xhx9pzhj 1516 9 by by IN cord-005646-xhx9pzhj 1516 10 the the DT cord-005646-xhx9pzhj 1516 11 standard standard JJ cord-005646-xhx9pzhj 1516 12 deviation deviation NN cord-005646-xhx9pzhj 1516 13 of of IN cord-005646-xhx9pzhj 1516 14 repeated repeat VBN cord-005646-xhx9pzhj 1516 15 measurements measurement NNS cord-005646-xhx9pzhj 1516 16 of of IN cord-005646-xhx9pzhj 1516 17 the the DT cord-005646-xhx9pzhj 1516 18 parameters parameter NNS cord-005646-xhx9pzhj 1516 19 as as IN cord-005646-xhx9pzhj 1516 20 calculated calculate VBN cord-005646-xhx9pzhj 1516 21 in in IN cord-005646-xhx9pzhj 1516 22 a a DT cord-005646-xhx9pzhj 1516 23 oneway oneway NN cord-005646-xhx9pzhj 1516 24 analysis analysis NN cord-005646-xhx9pzhj 1516 25 of of IN cord-005646-xhx9pzhj 1516 26 variance variance NN cord-005646-xhx9pzhj 1516 27 . . . cord-005646-xhx9pzhj 1517 1 Results result NNS cord-005646-xhx9pzhj 1517 2 . . . cord-005646-xhx9pzhj 1518 1 Mean mean JJ cord-005646-xhx9pzhj 1518 2 difference difference NN cord-005646-xhx9pzhj 1518 3 ( ( -LRB- cord-005646-xhx9pzhj 1518 4 Mdi Mdi NNP cord-005646-xhx9pzhj 1518 5 0 0 CD cord-005646-xhx9pzhj 1518 6 between between IN cord-005646-xhx9pzhj 1518 7 injected inject VBN cord-005646-xhx9pzhj 1518 8 V v NN cord-005646-xhx9pzhj 1518 9 ( ( -LRB- cord-005646-xhx9pzhj 1518 10 5 5 CD cord-005646-xhx9pzhj 1518 11 to to TO cord-005646-xhx9pzhj 1518 12 50 50 CD cord-005646-xhx9pzhj 1518 13 ml ml NNS cord-005646-xhx9pzhj 1518 14 ) ) -RRB- cord-005646-xhx9pzhj 1518 15 and and CC cord-005646-xhx9pzhj 1519 1 measured measure VBN cord-005646-xhx9pzhj 1519 2 V V NNP cord-005646-xhx9pzhj 1519 3 using use VBG cord-005646-xhx9pzhj 1519 4 PNT PNT NNP cord-005646-xhx9pzhj 1519 5 0 0 CD cord-005646-xhx9pzhj 1519 6 was be VBD cord-005646-xhx9pzhj 1519 7 0.15 0.15 CD cord-005646-xhx9pzhj 1519 8 ml ml NNS cord-005646-xhx9pzhj 1519 9 , , , cord-005646-xhx9pzhj 1519 10 SD SD NNP cord-005646-xhx9pzhj 1519 11 = = SYM cord-005646-xhx9pzhj 1519 12 0.13 0.13 CD cord-005646-xhx9pzhj 1519 13 ml ml NN cord-005646-xhx9pzhj 1519 14 . . . cord-005646-xhx9pzhj 1520 1 Difference difference NN cord-005646-xhx9pzhj 1520 2 and and CC cord-005646-xhx9pzhj 1521 1 mean mean JJ cord-005646-xhx9pzhj 1521 2 V V NNP cord-005646-xhx9pzhj 1521 3 were be VBD cord-005646-xhx9pzhj 1521 4 not not RB cord-005646-xhx9pzhj 1521 5 correlated correlate VBN cord-005646-xhx9pzhj 1521 6 . . . cord-005646-xhx9pzhj 1522 1 SD SD NNP cord-005646-xhx9pzhj 1522 2 of of IN cord-005646-xhx9pzhj 1522 3 repeated repeat VBN cord-005646-xhx9pzhj 1522 4 V v NN cord-005646-xhx9pzhj 1522 5 measurements measurement NNS cord-005646-xhx9pzhj 1522 6 were be VBD cord-005646-xhx9pzhj 1522 7 not not RB cord-005646-xhx9pzhj 1522 8 correlated correlate VBN cord-005646-xhx9pzhj 1522 9 to to IN cord-005646-xhx9pzhj 1522 10 V. V. NNP cord-005646-xhx9pzhj 1522 11 CR CR NNP cord-005646-xhx9pzhj 1522 12 was be VBD cord-005646-xhx9pzhj 1522 13 0.4 0.4 CD cord-005646-xhx9pzhj 1522 14 ml ml NN cord-005646-xhx9pzhj 1522 15 . . . cord-005646-xhx9pzhj 1523 1 Mdif Mdif NNP cord-005646-xhx9pzhj 1523 2 between between IN cord-005646-xhx9pzhj 1523 3 injected inject VBN cord-005646-xhx9pzhj 1523 4 V v NN cord-005646-xhx9pzhj 1523 5 ( ( -LRB- cord-005646-xhx9pzhj 1523 6 25 25 CD cord-005646-xhx9pzhj 1523 7 to to TO cord-005646-xhx9pzhj 1523 8 400 400 CD cord-005646-xhx9pzhj 1523 9 ml ml NNS cord-005646-xhx9pzhj 1523 10 ) ) -RRB- cord-005646-xhx9pzhj 1523 11 and and CC cord-005646-xhx9pzhj 1523 12 measured measure VBN cord-005646-xhx9pzhj 1523 13 V V NNP cord-005646-xhx9pzhj 1523 14 using use VBG cord-005646-xhx9pzhj 1523 15 PNT PNT NNP cord-005646-xhx9pzhj 1523 16 1 1 CD cord-005646-xhx9pzhj 1523 17 was be VBD cord-005646-xhx9pzhj 1523 18 3 3 CD cord-005646-xhx9pzhj 1523 19 lrd lrd NNP cord-005646-xhx9pzhj 1523 20 , , , cord-005646-xhx9pzhj 1523 21 SD SD NNP cord-005646-xhx9pzhj 1523 22 = = SYM cord-005646-xhx9pzhj 1523 23 6 6 CD cord-005646-xhx9pzhj 1523 24 mL ml NN cord-005646-xhx9pzhj 1523 25 SD sd NN cord-005646-xhx9pzhj 1523 26 of of IN cord-005646-xhx9pzhj 1523 27 repeated repeat VBN cord-005646-xhx9pzhj 1523 28 V v NN cord-005646-xhx9pzhj 1523 29 measurements measurement NNS cord-005646-xhx9pzhj 1523 30 were be VBD cord-005646-xhx9pzhj 1523 31 not not RB cord-005646-xhx9pzhj 1523 32 correlated correlate VBN cord-005646-xhx9pzhj 1523 33 to to TO cord-005646-xhx9pzhj 1523 34 mean mean VB cord-005646-xhx9pzhj 1523 35 V. V. NNP cord-005646-xhx9pzhj 1523 36 CR CR NNP cord-005646-xhx9pzhj 1523 37 was be VBD cord-005646-xhx9pzhj 1523 38 6 6 CD cord-005646-xhx9pzhj 1523 39 ml ml NN cord-005646-xhx9pzhj 1523 40 . . . cord-005646-xhx9pzhj 1524 1 Mdif Mdif NNP cord-005646-xhx9pzhj 1524 2 between between IN cord-005646-xhx9pzhj 1524 3 injected inject VBN cord-005646-xhx9pzhj 1524 4 P p NN cord-005646-xhx9pzhj 1524 5 and and CC cord-005646-xhx9pzhj 1524 6 measured measure VBN cord-005646-xhx9pzhj 1524 7 P P NNP cord-005646-xhx9pzhj 1524 8 was be VBD cord-005646-xhx9pzhj 1524 9 0.3 0.3 CD cord-005646-xhx9pzhj 1524 10 cmI cmI NNP cord-005646-xhx9pzhj 1524 11 - - HYPH cord-005646-xhx9pzhj 1524 12 I20 I20 NNP cord-005646-xhx9pzhj 1524 13 , , , cord-005646-xhx9pzhj 1524 14 SD SD NNP cord-005646-xhx9pzhj 1524 15 0.4 0.4 CD cord-005646-xhx9pzhj 1524 16 cm cm NNS cord-005646-xhx9pzhj 1524 17 H20 H20 NNP cord-005646-xhx9pzhj 1524 18 SD SD NNP cord-005646-xhx9pzhj 1524 19 of of IN cord-005646-xhx9pzhj 1524 20 repeated repeat VBN cord-005646-xhx9pzhj 1524 21 P p NN cord-005646-xhx9pzhj 1524 22 measurements measurement NNS cord-005646-xhx9pzhj 1524 23 were be VBD cord-005646-xhx9pzhj 1524 24 not not RB cord-005646-xhx9pzhj 1524 25 correlated correlate VBN cord-005646-xhx9pzhj 1524 26 to to TO cord-005646-xhx9pzhj 1524 27 mean mean VB cord-005646-xhx9pzhj 1524 28 P. P. NNP cord-005646-xhx9pzhj 1524 29 CR CR NNP cord-005646-xhx9pzhj 1524 30 was be VBD cord-005646-xhx9pzhj 1524 31 0.3 0.3 CD cord-005646-xhx9pzhj 1524 32 cmH20 cmH20 NNP cord-005646-xhx9pzhj 1524 33 . . . cord-005646-xhx9pzhj 1525 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1525 2 . . . cord-005646-xhx9pzhj 1526 1 Inexpensive inexpensive JJ cord-005646-xhx9pzhj 1526 2 piezoelectrical piezoelectrical JJ cord-005646-xhx9pzhj 1526 3 transducers transducer NNS cord-005646-xhx9pzhj 1526 4 can can MD cord-005646-xhx9pzhj 1526 5 be be VB cord-005646-xhx9pzhj 1526 6 used use VBN cord-005646-xhx9pzhj 1526 7 to to TO cord-005646-xhx9pzhj 1526 8 measure measure VB cord-005646-xhx9pzhj 1526 9 F F NNP cord-005646-xhx9pzhj 1526 10 and and CC cord-005646-xhx9pzhj 1526 11 P P NNP cord-005646-xhx9pzhj 1526 12 and and CC cord-005646-xhx9pzhj 1526 13 evaluate evaluate VB cord-005646-xhx9pzhj 1526 14 respiratory respiratory JJ cord-005646-xhx9pzhj 1526 15 mechanics mechanic NNS cord-005646-xhx9pzhj 1526 16 in in IN cord-005646-xhx9pzhj 1526 17 ventilated ventilate VBN cord-005646-xhx9pzhj 1526 18 children child NNS cord-005646-xhx9pzhj 1526 19 . . . cord-005646-xhx9pzhj 1527 1 Previous previous JJ cord-005646-xhx9pzhj 1527 2 studies study NNS cord-005646-xhx9pzhj 1527 3 have have VBP cord-005646-xhx9pzhj 1527 4 already already RB cord-005646-xhx9pzhj 1527 5 shown show VBN cord-005646-xhx9pzhj 1527 6 the the DT cord-005646-xhx9pzhj 1527 7 problem problem NN cord-005646-xhx9pzhj 1527 8 of of IN cord-005646-xhx9pzhj 1527 9 the the DT cord-005646-xhx9pzhj 1527 10 reproducibility reproducibility NN cord-005646-xhx9pzhj 1527 11 of of IN cord-005646-xhx9pzhj 1527 12 PFT PFT NNP cord-005646-xhx9pzhj 1527 13 in in IN cord-005646-xhx9pzhj 1527 14 preterm preterm NNS cord-005646-xhx9pzhj 1527 15 ventilated ventilate VBN cord-005646-xhx9pzhj 1527 16 babies baby NNS cord-005646-xhx9pzhj 1527 17 . . . cord-005646-xhx9pzhj 1528 1 Were be VBD cord-005646-xhx9pzhj 1528 2 studied study VBN cord-005646-xhx9pzhj 1528 3 10 10 CD cord-005646-xhx9pzhj 1528 4 preterm preterm NNS cord-005646-xhx9pzhj 1528 5 ventilated ventilate VBN cord-005646-xhx9pzhj 1528 6 babies baby NNS cord-005646-xhx9pzhj 1528 7 { { -LRB- cord-005646-xhx9pzhj 1528 8 mean mean JJ cord-005646-xhx9pzhj 1528 9 weight weight NN cord-005646-xhx9pzhj 1528 10 1128 1128 CD cord-005646-xhx9pzhj 1528 11 gr gr NNP cord-005646-xhx9pzhj 1528 12 ) ) -RRB- cord-005646-xhx9pzhj 1528 13 in in IN cord-005646-xhx9pzhj 1528 14 the the DT cord-005646-xhx9pzhj 1528 15 first first JJ cord-005646-xhx9pzhj 1528 16 week week NN cord-005646-xhx9pzhj 1528 17 of of IN cord-005646-xhx9pzhj 1528 18 life life NN cord-005646-xhx9pzhj 1528 19 in in IN cord-005646-xhx9pzhj 1528 20 clinically clinically RB cord-005646-xhx9pzhj 1528 21 stable stable JJ cord-005646-xhx9pzhj 1528 22 condition condition NN cord-005646-xhx9pzhj 1528 23 , , , cord-005646-xhx9pzhj 1528 24 measuring measure VBG cord-005646-xhx9pzhj 1528 25 flow flow NN cord-005646-xhx9pzhj 1528 26 , , , cord-005646-xhx9pzhj 1528 27 airway airway NN cord-005646-xhx9pzhj 1528 28 pressure pressure NN cord-005646-xhx9pzhj 1528 29 and and CC cord-005646-xhx9pzhj 1528 30 esophageal esophageal JJ cord-005646-xhx9pzhj 1528 31 pressure pressure NN cord-005646-xhx9pzhj 1528 32 simultaneously simultaneously RB cord-005646-xhx9pzhj 1528 33 . . . cord-005646-xhx9pzhj 1529 1 Each each DT cord-005646-xhx9pzhj 1529 2 baby baby NN cord-005646-xhx9pzhj 1529 3 was be VBD cord-005646-xhx9pzhj 1529 4 studied study VBN cord-005646-xhx9pzhj 1529 5 twice twice RB cord-005646-xhx9pzhj 1529 6 with with IN cord-005646-xhx9pzhj 1529 7 an an DT cord-005646-xhx9pzhj 1529 8 interval interval NN cord-005646-xhx9pzhj 1529 9 of of IN cord-005646-xhx9pzhj 1529 10 one one CD cord-005646-xhx9pzhj 1529 11 hour hour NN cord-005646-xhx9pzhj 1529 12 and and CC cord-005646-xhx9pzhj 1529 13 each each DT cord-005646-xhx9pzhj 1529 14 study study NN cord-005646-xhx9pzhj 1529 15 was be VBD cord-005646-xhx9pzhj 1529 16 done do VBN cord-005646-xhx9pzhj 1529 17 increasing increase VBG cord-005646-xhx9pzhj 1529 18 the the DT cord-005646-xhx9pzhj 1529 19 rate rate NN cord-005646-xhx9pzhj 1529 20 till till IN cord-005646-xhx9pzhj 1529 21 60 60 CD cord-005646-xhx9pzhj 1529 22 to to TO cord-005646-xhx9pzhj 1529 23 inhibit inhibit VB cord-005646-xhx9pzhj 1529 24 spontaneous spontaneous JJ cord-005646-xhx9pzhj 1529 25 breaths breath NNS cord-005646-xhx9pzhj 1529 26 . . . cord-005646-xhx9pzhj 1530 1 None none NN cord-005646-xhx9pzhj 1530 2 sedative sedative NN cord-005646-xhx9pzhj 1530 3 has have VBZ cord-005646-xhx9pzhj 1530 4 been be VBN cord-005646-xhx9pzhj 1530 5 used use VBN cord-005646-xhx9pzhj 1530 6 . . . cord-005646-xhx9pzhj 1531 1 Only only JJ cord-005646-xhx9pzhj 1531 2 mechanical mechanical JJ cord-005646-xhx9pzhj 1531 3 breaths breath NNS cord-005646-xhx9pzhj 1531 4 were be VBD cord-005646-xhx9pzhj 1531 5 analyzed analyze VBN cord-005646-xhx9pzhj 1531 6 . . . cord-005646-xhx9pzhj 1532 1 Compliance compliance NN cord-005646-xhx9pzhj 1532 2 and and CC cord-005646-xhx9pzhj 1532 3 resistence resistence NN cord-005646-xhx9pzhj 1532 4 were be VBD cord-005646-xhx9pzhj 1532 5 calculated calculate VBN cord-005646-xhx9pzhj 1532 6 with with IN cord-005646-xhx9pzhj 1532 7 a a DT cord-005646-xhx9pzhj 1532 8 computer computer NN cord-005646-xhx9pzhj 1532 9 system system NN cord-005646-xhx9pzhj 1532 10 using use VBG cord-005646-xhx9pzhj 1532 11 the the DT cord-005646-xhx9pzhj 1532 12 linear linear JJ cord-005646-xhx9pzhj 1532 13 regression regression NN cord-005646-xhx9pzhj 1532 14 method method NN cord-005646-xhx9pzhj 1532 15 . . . cord-005646-xhx9pzhj 1533 1 We -PRON- PRP cord-005646-xhx9pzhj 1533 2 expressed express VBD cord-005646-xhx9pzhj 1533 3 quantitatively quantitatively RB cord-005646-xhx9pzhj 1533 4 the the DT cord-005646-xhx9pzhj 1533 5 intrapatient intrapatient JJ cord-005646-xhx9pzhj 1533 6 variability variability NN cord-005646-xhx9pzhj 1533 7 as as IN cord-005646-xhx9pzhj 1533 8 the the DT cord-005646-xhx9pzhj 1533 9 percentage percentage NN cord-005646-xhx9pzhj 1533 10 of of IN cord-005646-xhx9pzhj 1533 11 variation variation NN cord-005646-xhx9pzhj 1533 12 of of IN cord-005646-xhx9pzhj 1533 13 tidal tidal JJ cord-005646-xhx9pzhj 1533 14 volume volume NN cord-005646-xhx9pzhj 1533 15 , , , cord-005646-xhx9pzhj 1533 16 compliance compliance NN cord-005646-xhx9pzhj 1533 17 and and CC cord-005646-xhx9pzhj 1533 18 resistence resistence NN cord-005646-xhx9pzhj 1533 19 between between IN cord-005646-xhx9pzhj 1533 20 the the DT cord-005646-xhx9pzhj 1533 21 two two CD cord-005646-xhx9pzhj 1533 22 studies study NNS cord-005646-xhx9pzhj 1533 23 in in IN cord-005646-xhx9pzhj 1533 24 each each DT cord-005646-xhx9pzhj 1533 25 baby baby NN cord-005646-xhx9pzhj 1533 26 . . . cord-005646-xhx9pzhj 1534 1 Then then RB cord-005646-xhx9pzhj 1534 2 Intraclass Intraclass NNP cord-005646-xhx9pzhj 1534 3 correlation correlation NN cord-005646-xhx9pzhj 1534 4 coefficient coefficient NN cord-005646-xhx9pzhj 1534 5 test test NN cord-005646-xhx9pzhj 1534 6 ( ( -LRB- cord-005646-xhx9pzhj 1534 7 ICC ICC NNP cord-005646-xhx9pzhj 1534 8 ) ) -RRB- cord-005646-xhx9pzhj 1534 9 was be VBD cord-005646-xhx9pzhj 1534 10 applied apply VBN cord-005646-xhx9pzhj 1534 11 to to TO cord-005646-xhx9pzhj 1534 12 confirm confirm VB cord-005646-xhx9pzhj 1534 13 qualitatively qualitatively RB cord-005646-xhx9pzhj 1534 14 our -PRON- PRP$ cord-005646-xhx9pzhj 1534 15 results result NNS cord-005646-xhx9pzhj 1534 16 ( ( -LRB- cord-005646-xhx9pzhj 1534 17 total total JJ cord-005646-xhx9pzhj 1534 18 agreement agreement NN cord-005646-xhx9pzhj 1534 19 = = SYM cord-005646-xhx9pzhj 1534 20 1 1 CD cord-005646-xhx9pzhj 1534 21 , , , cord-005646-xhx9pzhj 1534 22 good good JJ cord-005646-xhx9pzhj 1534 23 reproducibJtity reproducibjtity NN cord-005646-xhx9pzhj 1534 24 > > XX cord-005646-xhx9pzhj 1534 25 0.75 0.75 CD cord-005646-xhx9pzhj 1534 26 ) ) -RRB- cord-005646-xhx9pzhj 1534 27 . . . cord-005646-xhx9pzhj 1535 1 We -PRON- PRP cord-005646-xhx9pzhj 1535 2 h~£ed h~£ed VBP cord-005646-xhx9pzhj 1535 3 , , , cord-005646-xhx9pzhj 1535 4 an an DT cord-005646-xhx9pzhj 1535 5 a6Eept a6Eept NNP cord-005646-xhx9pzhj 1535 6 ~ ~ NFP cord-005646-xhx9pzhj 1535 7 ble ble JJ cord-005646-xhx9pzhj 1535 8 ~Efiabirl¢ ~Efiabirl¢ NNP cord-005646-xhx9pzhj 1535 9 , , , cord-005646-xhx9pzhj 1535 10 ~-~r;= ~-~r;= XX cord-005646-xhx9pzhj 1535 11 ' ' '' cord-005646-xhx9pzhj 1535 12 ~ ~ NFP cord-005646-xhx9pzhj 1535 13 . . . cord-005646-xhx9pzhj 1536 1 During during IN cord-005646-xhx9pzhj 1536 2 mechanical mechanical JJ cord-005646-xhx9pzhj 1536 3 ventilation ventilation NN cord-005646-xhx9pzhj 1536 4 , , , cord-005646-xhx9pzhj 1536 5 an an DT cord-005646-xhx9pzhj 1536 6 air air NN cord-005646-xhx9pzhj 1536 7 leak leak NN cord-005646-xhx9pzhj 1536 8 ( ( -LRB- cord-005646-xhx9pzhj 1536 9 AL AL NNP cord-005646-xhx9pzhj 1536 10 ) ) -RRB- cord-005646-xhx9pzhj 1536 11 and and CC cord-005646-xhx9pzhj 1536 12 plateau plateau NN cord-005646-xhx9pzhj 1536 13 phase phase NN cord-005646-xhx9pzhj 1536 14 duration duration NN cord-005646-xhx9pzhj 1536 15 ( ( -LRB- cord-005646-xhx9pzhj 1536 16 PL pl NN cord-005646-xhx9pzhj 1536 17 ) ) -RRB- cord-005646-xhx9pzhj 1536 18 may may MD cord-005646-xhx9pzhj 1536 19 influence influence VB cord-005646-xhx9pzhj 1536 20 dynamic dynamic JJ cord-005646-xhx9pzhj 1536 21 and and CC cord-005646-xhx9pzhj 1536 22 static static JJ cord-005646-xhx9pzhj 1536 23 compliance compliance NN cord-005646-xhx9pzhj 1537 1 ( ( -LRB- cord-005646-xhx9pzhj 1537 2 Cdy Cdy NNP cord-005646-xhx9pzhj 1537 3 and and CC cord-005646-xhx9pzhj 1537 4 Cst Cst NNP cord-005646-xhx9pzhj 1537 5 , , , cord-005646-xhx9pzhj 1537 6 respectively respectively RB cord-005646-xhx9pzhj 1537 7 ) ) -RRB- cord-005646-xhx9pzhj 1537 8 . . . cord-005646-xhx9pzhj 1538 1 This this DT cord-005646-xhx9pzhj 1538 2 study study NN cord-005646-xhx9pzhj 1538 3 evaluated evaluate VBD cord-005646-xhx9pzhj 1538 4 the the DT cord-005646-xhx9pzhj 1538 5 effect effect NN cord-005646-xhx9pzhj 1538 6 of of IN cord-005646-xhx9pzhj 1538 7 AL AL NNP cord-005646-xhx9pzhj 1538 8 and and CC cord-005646-xhx9pzhj 1538 9 PL PL NNP cord-005646-xhx9pzhj 1538 10 on on IN cord-005646-xhx9pzhj 1538 11 two two CD cord-005646-xhx9pzhj 1538 12 methods method NNS cord-005646-xhx9pzhj 1538 13 of of IN cord-005646-xhx9pzhj 1538 14 measuring measure VBG cord-005646-xhx9pzhj 1538 15 C.dy C.dy NNP cord-005646-xhx9pzhj 1538 16 and and CC cord-005646-xhx9pzhj 1538 17 est est NN cord-005646-xhx9pzhj 1538 18 . . . cord-005646-xhx9pzhj 1539 1 Methods method NNS cord-005646-xhx9pzhj 1539 2 . . . cord-005646-xhx9pzhj 1540 1 13 13 CD cord-005646-xhx9pzhj 1540 2 intubated intubate VBN cord-005646-xhx9pzhj 1540 3 , , , cord-005646-xhx9pzhj 1540 4 ventilated ventilate VBN cord-005646-xhx9pzhj 1540 5 patients patient NNS cord-005646-xhx9pzhj 1540 6 in in IN cord-005646-xhx9pzhj 1540 7 a a DT cord-005646-xhx9pzhj 1540 8 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1540 9 Intensive Intensive NNP cord-005646-xhx9pzhj 1540 10 Care Care NNP cord-005646-xhx9pzhj 1540 11 Unit Unit NNP cord-005646-xhx9pzhj 1540 12 were be VBD cord-005646-xhx9pzhj 1540 13 evaluated evaluate VBN cord-005646-xhx9pzhj 1540 14 after after IN cord-005646-xhx9pzhj 1540 15 obtaining obtain VBG cord-005646-xhx9pzhj 1540 16 Informed Informed NNP cord-005646-xhx9pzhj 1540 17 consent consent NN cord-005646-xhx9pzhj 1540 18 . . . cord-005646-xhx9pzhj 1541 1 Patients patient NNS cord-005646-xhx9pzhj 1541 2 were be VBD cord-005646-xhx9pzhj 1541 3 intuhated intuhate VBN cord-005646-xhx9pzhj 1541 4 with with IN cord-005646-xhx9pzhj 1541 5 a a DT cord-005646-xhx9pzhj 1541 6 cuffed cuff VBN cord-005646-xhx9pzhj 1541 7 endotracheal endotracheal NN cord-005646-xhx9pzhj 1541 8 tube tube NN cord-005646-xhx9pzhj 1541 9 and and CC cord-005646-xhx9pzhj 1541 10 ventilated ventilate VBN cord-005646-xhx9pzhj 1541 11 with with IN cord-005646-xhx9pzhj 1541 12 a a DT cord-005646-xhx9pzhj 1541 13 Serve Serve NNP cord-005646-xhx9pzhj 1541 14 900(2 900(2 CD cord-005646-xhx9pzhj 1541 15 ventilator ventilator NN cord-005646-xhx9pzhj 1541 16 . . . cord-005646-xhx9pzhj 1542 1 Cdy Cdy NNP cord-005646-xhx9pzhj 1542 2 and and CC cord-005646-xhx9pzhj 1542 3 Cst Cst NNP cord-005646-xhx9pzhj 1542 4 were be VBD cord-005646-xhx9pzhj 1542 5 determined determine VBN cord-005646-xhx9pzhj 1542 6 using use VBG cord-005646-xhx9pzhj 1542 7 the the DT cord-005646-xhx9pzhj 1542 8 Serve Serve NNP cord-005646-xhx9pzhj 1542 9 andS andS -RRB- cord-005646-xhx9pzhj 1542 10 ~ ~ CD cord-005646-xhx9pzhj 1542 11 rMedics rmedic NNS cord-005646-xhx9pzhj 1542 12 2600 2600 CD cord-005646-xhx9pzhj 1542 13 . . . cord-005646-xhx9pzhj 1543 1 Objective objective NN cord-005646-xhx9pzhj 1543 2 : : : cord-005646-xhx9pzhj 1543 3 evaluate evaluate VB cord-005646-xhx9pzhj 1543 4 the the DT cord-005646-xhx9pzhj 1543 5 repercussion repercussion NN cord-005646-xhx9pzhj 1543 6 in in IN cord-005646-xhx9pzhj 1543 7 respiratory respiratory JJ cord-005646-xhx9pzhj 1543 8 mechanics mechanic NNS cord-005646-xhx9pzhj 1543 9 and and CC cord-005646-xhx9pzhj 1543 10 arterial arterial JJ cord-005646-xhx9pzhj 1543 11 blood blood NN cord-005646-xhx9pzhj 1543 12 gases gas NNS cord-005646-xhx9pzhj 1543 13 and and CC cord-005646-xhx9pzhj 1543 14 the the DT cord-005646-xhx9pzhj 1543 15 impact impact NN cord-005646-xhx9pzhj 1543 16 of of IN cord-005646-xhx9pzhj 1543 17 the the DT cord-005646-xhx9pzhj 1543 18 ventilator ventilator NN cord-005646-xhx9pzhj 1543 19 adjustments adjustment NNS cord-005646-xhx9pzhj 1543 20 on on IN cord-005646-xhx9pzhj 1543 21 the the DT cord-005646-xhx9pzhj 1543 22 auto auto NN cord-005646-xhx9pzhj 1543 23 - - HYPH cord-005646-xhx9pzhj 1543 24 PEEP peep NN cord-005646-xhx9pzhj 1543 25 magnitude magnitude NN cord-005646-xhx9pzhj 1543 26 . . . cord-005646-xhx9pzhj 1544 1 Material material NN cord-005646-xhx9pzhj 1544 2 and and CC cord-005646-xhx9pzhj 1544 3 Methods Methods NNPS cord-005646-xhx9pzhj 1544 4 : : : cord-005646-xhx9pzhj 1544 5 the the DT cord-005646-xhx9pzhj 1544 6 measurement measurement NN cord-005646-xhx9pzhj 1544 7 of of IN cord-005646-xhx9pzhj 1544 8 the the DT cord-005646-xhx9pzhj 1544 9 auto auto NN cord-005646-xhx9pzhj 1544 10 - - HYPH cord-005646-xhx9pzhj 1544 11 PEEP PEEP NNP cord-005646-xhx9pzhj 1544 12 was be VBD cord-005646-xhx9pzhj 1544 13 performed perform VBN cord-005646-xhx9pzhj 1544 14 using use VBG cord-005646-xhx9pzhj 1544 15 an an DT cord-005646-xhx9pzhj 1544 16 eletronic eletronic JJ cord-005646-xhx9pzhj 1544 17 - - HYPH cord-005646-xhx9pzhj 1544 18 pneumatic pneumatic JJ cord-005646-xhx9pzhj 1544 19 controlled control VBN cord-005646-xhx9pzhj 1544 20 device device NN cord-005646-xhx9pzhj 1544 21 with with IN cord-005646-xhx9pzhj 1544 22 a a DT cord-005646-xhx9pzhj 1544 23 oclasion oclasion NN cord-005646-xhx9pzhj 1544 24 valve valve NN cord-005646-xhx9pzhj 1544 25 installed instal VBN cord-005646-xhx9pzhj 1544 26 between between IN cord-005646-xhx9pzhj 1544 27 endotracheal endotracheal NN cord-005646-xhx9pzhj 1544 28 canutla canutla NNP cord-005646-xhx9pzhj 1544 29 and and CC cord-005646-xhx9pzhj 1544 30 the the DT cord-005646-xhx9pzhj 1544 31 ventilator ventilator NN cord-005646-xhx9pzhj 1544 32 circuit circuit NN cord-005646-xhx9pzhj 1544 33 . . . cord-005646-xhx9pzhj 1545 1 The the DT cord-005646-xhx9pzhj 1545 2 d~'ice d~'ice NNP cord-005646-xhx9pzhj 1545 3 was be VBD cord-005646-xhx9pzhj 1545 4 connected connect VBN cord-005646-xhx9pzhj 1545 5 to to IN cord-005646-xhx9pzhj 1545 6 a a DT cord-005646-xhx9pzhj 1545 7 solenoid solenoid NN cord-005646-xhx9pzhj 1545 8 to to TO cord-005646-xhx9pzhj 1545 9 detecte detecte VB cord-005646-xhx9pzhj 1545 10 the the DT cord-005646-xhx9pzhj 1545 11 end end NN cord-005646-xhx9pzhj 1545 12 of of IN cord-005646-xhx9pzhj 1545 13 inspiratuo inspiratuo JJ cord-005646-xhx9pzhj 1545 14 phase phase NN cord-005646-xhx9pzhj 1545 15 and and CC cord-005646-xhx9pzhj 1545 16 thus thus RB cord-005646-xhx9pzhj 1545 17 , , , cord-005646-xhx9pzhj 1545 18 the the DT cord-005646-xhx9pzhj 1545 19 activation activation NN cord-005646-xhx9pzhj 1545 20 of of IN cord-005646-xhx9pzhj 1545 21 the the DT cord-005646-xhx9pzhj 1545 22 oclusion oclusion NN cord-005646-xhx9pzhj 1545 23 valve valve NN cord-005646-xhx9pzhj 1545 24 . . . cord-005646-xhx9pzhj 1546 1 The the DT cord-005646-xhx9pzhj 1546 2 signs sign NNS cord-005646-xhx9pzhj 1546 3 of of IN cord-005646-xhx9pzhj 1546 4 pressure pressure NN cord-005646-xhx9pzhj 1546 5 and and CC cord-005646-xhx9pzhj 1546 6 flow flow NN cord-005646-xhx9pzhj 1546 7 were be VBD cord-005646-xhx9pzhj 1546 8 monitorized monitorize VBN cord-005646-xhx9pzhj 1546 9 using use VBG cord-005646-xhx9pzhj 1546 10 a a DT cord-005646-xhx9pzhj 1546 11 diferential diferential JJ cord-005646-xhx9pzhj 1546 12 transducer transducer NN cord-005646-xhx9pzhj 1546 13 and and CC cord-005646-xhx9pzhj 1546 14 it -PRON- PRP cord-005646-xhx9pzhj 1546 15 was be VBD cord-005646-xhx9pzhj 1546 16 processed process VBN cord-005646-xhx9pzhj 1546 17 using use VBG cord-005646-xhx9pzhj 1546 18 a a DT cord-005646-xhx9pzhj 1546 19 PC pc NN cord-005646-xhx9pzhj 1546 20 computer computer NN cord-005646-xhx9pzhj 1546 21 and and CC cord-005646-xhx9pzhj 1546 22 tMeumoview tMeumoview NNP cord-005646-xhx9pzhj 1547 1 ® ® LS cord-005646-xhx9pzhj 1547 2 software software NN cord-005646-xhx9pzhj 1547 3 . . . cord-005646-xhx9pzhj 1548 1 The the DT cord-005646-xhx9pzhj 1548 2 stud3 stud3 NN cord-005646-xhx9pzhj 1548 3 were be VBD cord-005646-xhx9pzhj 1548 4 divided divide VBN cord-005646-xhx9pzhj 1548 5 in in IN cord-005646-xhx9pzhj 1548 6 2 2 CD cord-005646-xhx9pzhj 1548 7 phases phase NNS cord-005646-xhx9pzhj 1548 8 : : : cord-005646-xhx9pzhj 1548 9 phase phase NN cord-005646-xhx9pzhj 1548 10 A. a. NN cord-005646-xhx9pzhj 1548 11 where where WRB cord-005646-xhx9pzhj 1548 12 the the DT cord-005646-xhx9pzhj 1548 13 ventilator ventilator NN cord-005646-xhx9pzhj 1548 14 adjustments adjustment NNS cord-005646-xhx9pzhj 1548 15 was be VBD cord-005646-xhx9pzhj 1548 16 performed perform VBN cord-005646-xhx9pzhj 1548 17 using use VBG cord-005646-xhx9pzhj 1548 18 the the DT cord-005646-xhx9pzhj 1548 19 routine routine NN cord-005646-xhx9pzhj 1548 20 of of IN cord-005646-xhx9pzhj 1548 21 the the DT cord-005646-xhx9pzhj 1548 22 unit unit NN cord-005646-xhx9pzhj 1548 23 and and CC cord-005646-xhx9pzhj 1548 24 phase phase NN cord-005646-xhx9pzhj 1548 25 B b NN cord-005646-xhx9pzhj 1548 26 , , , cord-005646-xhx9pzhj 1548 27 where where WRB cord-005646-xhx9pzhj 1548 28 the the DT cord-005646-xhx9pzhj 1548 29 targets target NNS cord-005646-xhx9pzhj 1548 30 of of IN cord-005646-xhx9pzhj 1548 31 mechanical mechanical JJ cord-005646-xhx9pzhj 1548 32 ventilation ventilation NN cord-005646-xhx9pzhj 1548 33 were be VBD cord-005646-xhx9pzhj 1548 34 to to TO cord-005646-xhx9pzhj 1548 35 minimize minimize VB cord-005646-xhx9pzhj 1548 36 the the DT cord-005646-xhx9pzhj 1548 37 auto auto NN cord-005646-xhx9pzhj 1548 38 - - HYPH cord-005646-xhx9pzhj 1548 39 PEEP peep NN cord-005646-xhx9pzhj 1548 40 . . . cord-005646-xhx9pzhj 1549 1 Static static JJ cord-005646-xhx9pzhj 1549 2 compliance compliance NN cord-005646-xhx9pzhj 1549 3 ( ( -LRB- cord-005646-xhx9pzhj 1549 4 Crs Crs NNP cord-005646-xhx9pzhj 1549 5 ) ) -RRB- cord-005646-xhx9pzhj 1549 6 was be VBD cord-005646-xhx9pzhj 1549 7 ineasured ineasure VBN cord-005646-xhx9pzhj 1549 8 by by IN cord-005646-xhx9pzhj 1549 9 the the DT cord-005646-xhx9pzhj 1549 10 single single JJ cord-005646-xhx9pzhj 1549 11 - - HYPH cord-005646-xhx9pzhj 1549 12 breath breath NN cord-005646-xhx9pzhj 1549 13 occlusion occlusion NN cord-005646-xhx9pzhj 1549 14 technique technique NN cord-005646-xhx9pzhj 1549 15 , , , cord-005646-xhx9pzhj 1549 16 using use VBG cord-005646-xhx9pzhj 1549 17 a a DT cord-005646-xhx9pzhj 1549 18 mean mean NN cord-005646-xhx9pzhj 1549 19 of of IN cord-005646-xhx9pzhj 1549 20 ten ten CD cord-005646-xhx9pzhj 1549 21 occlusions occlusion NNS cord-005646-xhx9pzhj 1549 22 for for IN cord-005646-xhx9pzhj 1549 23 analysis analysis NN cord-005646-xhx9pzhj 1549 24 . . . cord-005646-xhx9pzhj 1550 1 Passive passive JJ cord-005646-xhx9pzhj 1550 2 respiratory respiratory JJ cord-005646-xhx9pzhj 1550 3 resistance resistance NN cord-005646-xhx9pzhj 1550 4 measurements measurement NNS cord-005646-xhx9pzhj 1550 5 and and CC cord-005646-xhx9pzhj 1550 6 the the DT cord-005646-xhx9pzhj 1550 7 tidal tidal JJ cord-005646-xhx9pzhj 1550 8 breathing breathing NN cord-005646-xhx9pzhj 1550 9 flow flow NN cord-005646-xhx9pzhj 1550 10 - - HYPH cord-005646-xhx9pzhj 1550 11 volume volume NN cord-005646-xhx9pzhj 1550 12 loops loop NNS cord-005646-xhx9pzhj 1550 13 were be VBD cord-005646-xhx9pzhj 1550 14 also also RB cord-005646-xhx9pzhj 1550 15 obtained obtain VBN cord-005646-xhx9pzhj 1550 16 . . . cord-005646-xhx9pzhj 1551 1 , , , cord-005646-xhx9pzhj 1551 2 while while IN cord-005646-xhx9pzhj 1551 3 the the DT cord-005646-xhx9pzhj 1551 4 ventilatory ventilatory JJ cord-005646-xhx9pzhj 1551 5 settings setting NNS cord-005646-xhx9pzhj 1551 6 were be VBD cord-005646-xhx9pzhj 1551 7 siguificantly siguificantly RB cord-005646-xhx9pzhj 1551 8 reduced reduce VBN cord-005646-xhx9pzhj 1551 9 soon soon RB cord-005646-xhx9pzhj 1551 10 atier atier RBR cord-005646-xhx9pzhj 1551 11 ECMO ECMO NNP cord-005646-xhx9pzhj 1551 12 was be VBD cord-005646-xhx9pzhj 1551 13 started start VBN cord-005646-xhx9pzhj 1551 14 . . . cord-005646-xhx9pzhj 1552 1 Before before IN cord-005646-xhx9pzhj 1552 2 ECMO ECMO NNP cord-005646-xhx9pzhj 1552 3 Crs Crs NNP cord-005646-xhx9pzhj 1552 4 measured measure VBN cord-005646-xhx9pzhj 1552 5 in in IN cord-005646-xhx9pzhj 1552 6 all all DT cord-005646-xhx9pzhj 1552 7 patienls patienls NN cord-005646-xhx9pzhj 1552 8 was be VBD cord-005646-xhx9pzhj 1552 9 0.23_+t).03 0.23_+t).03 CD cord-005646-xhx9pzhj 1552 10 ml ml NN cord-005646-xhx9pzhj 1552 11 / / SYM cord-005646-xhx9pzhj 1552 12 cmH20 cmH20 NNP cord-005646-xhx9pzhj 1552 13 / / SYM cord-005646-xhx9pzhj 1552 14 kg kg NNP cord-005646-xhx9pzhj 1552 15 ( ( -LRB- cord-005646-xhx9pzhj 1552 16 mean_+SEM mean_+SEM NNP cord-005646-xhx9pzhj 1552 17 ) ) -RRB- cord-005646-xhx9pzhj 1552 18 . . . cord-005646-xhx9pzhj 1553 1 For for IN cord-005646-xhx9pzhj 1553 2 each each DT cord-005646-xhx9pzhj 1553 3 patient patient NN cord-005646-xhx9pzhj 1553 4 the the DT cord-005646-xhx9pzhj 1553 5 ECMO ECMO NNP cord-005646-xhx9pzhj 1553 6 course course NN cord-005646-xhx9pzhj 1553 7 was be VBD cord-005646-xhx9pzhj 1553 8 divided divide VBN cord-005646-xhx9pzhj 1553 9 into into IN cord-005646-xhx9pzhj 1553 10 four four CD cord-005646-xhx9pzhj 1553 11 periods period NNS cord-005646-xhx9pzhj 1553 12 , , , cord-005646-xhx9pzhj 1553 13 proportional proportional JJ cord-005646-xhx9pzhj 1553 14 to to IN cord-005646-xhx9pzhj 1553 15 the the DT cord-005646-xhx9pzhj 1553 16 duration duration NN cord-005646-xhx9pzhj 1553 17 of of IN cord-005646-xhx9pzhj 1553 18 the the DT cord-005646-xhx9pzhj 1553 19 treatment treatment NN cord-005646-xhx9pzhj 1553 20 , , , cord-005646-xhx9pzhj 1553 21 and and CC cord-005646-xhx9pzhj 1553 22 the the DT cord-005646-xhx9pzhj 1553 23 best good JJS cord-005646-xhx9pzhj 1553 24 ~alue ~alue NFP cord-005646-xhx9pzhj 1553 25 of of IN cord-005646-xhx9pzhj 1553 26 Crs Crs NNP cord-005646-xhx9pzhj 1553 27 in in IN cord-005646-xhx9pzhj 1553 28 each each DT cord-005646-xhx9pzhj 1553 29 period period NN cord-005646-xhx9pzhj 1553 30 was be VBD cord-005646-xhx9pzhj 1553 31 chosen choose VBN cord-005646-xhx9pzhj 1553 32 for for IN cord-005646-xhx9pzhj 1553 33 analysis analysis NN cord-005646-xhx9pzhj 1553 34 . . . cord-005646-xhx9pzhj 1554 1 As as IN cord-005646-xhx9pzhj 1554 2 shown show VBN cord-005646-xhx9pzhj 1554 3 on on IN cord-005646-xhx9pzhj 1554 4 the the DT cord-005646-xhx9pzhj 1554 5 figure figure NN cord-005646-xhx9pzhj 1554 6 . . . cord-005646-xhx9pzhj 1555 1 Crs Crs NNP cord-005646-xhx9pzhj 1555 2 significantly significantly RB cord-005646-xhx9pzhj 1555 3 improved improve VBD cord-005646-xhx9pzhj 1555 4 ( ( -LRB- cord-005646-xhx9pzhj 1555 5 * * NFP cord-005646-xhx9pzhj 1555 6 p<0,05 p<0,05 NNP cord-005646-xhx9pzhj 1555 7 ) ) -RRB- cord-005646-xhx9pzhj 1555 8 from from IN cord-005646-xhx9pzhj 1555 9 the the DT cord-005646-xhx9pzhj 1555 10 second second JJ cord-005646-xhx9pzhj 1555 11 half half NN cord-005646-xhx9pzhj 1555 12 of of IN cord-005646-xhx9pzhj 1555 13 the the DT cord-005646-xhx9pzhj 1555 14 ECMO ECMO NNP cord-005646-xhx9pzhj 1555 15 course course NN cord-005646-xhx9pzhj 1555 16 in in IN cord-005646-xhx9pzhj 1555 17 the the DT cord-005646-xhx9pzhj 1555 18 group group NN cord-005646-xhx9pzhj 1555 19 of of IN cord-005646-xhx9pzhj 1555 20 patient patient NN cord-005646-xhx9pzhj 1555 21 that that WDT cord-005646-xhx9pzhj 1555 22 finally finally RB cord-005646-xhx9pzhj 1555 23 were be VBD cord-005646-xhx9pzhj 1555 24 successfidly successfidly RB cord-005646-xhx9pzhj 1555 25 weaned wean VBN cord-005646-xhx9pzhj 1555 26 from from IN cord-005646-xhx9pzhj 1555 27 ECMO ECMO NNP cord-005646-xhx9pzhj 1555 28 . . . cord-005646-xhx9pzhj 1556 1 No no DT cord-005646-xhx9pzhj 1556 2 change change NN cord-005646-xhx9pzhj 1556 3 ill ill JJ cord-005646-xhx9pzhj 1556 4 compliance compliance NN cord-005646-xhx9pzhj 1556 5 was be VBD cord-005646-xhx9pzhj 1556 6 measured measure VBN cord-005646-xhx9pzhj 1556 7 in in IN cord-005646-xhx9pzhj 1556 8 the the DT cord-005646-xhx9pzhj 1556 9 group group NN cord-005646-xhx9pzhj 1556 10 of of IN cord-005646-xhx9pzhj 1556 11 patients patient NNS cord-005646-xhx9pzhj 1556 12 who who WP cord-005646-xhx9pzhj 1556 13 failed fail VBD cord-005646-xhx9pzhj 1556 14 to to TO cord-005646-xhx9pzhj 1556 15 respond respond VB cord-005646-xhx9pzhj 1556 16 to to IN cord-005646-xhx9pzhj 1556 17 the the DT cord-005646-xhx9pzhj 1556 18 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 1556 19 hmg hmg NNP cord-005646-xhx9pzhj 1556 20 support support VB cord-005646-xhx9pzhj 1556 21 Our -PRON- PRP$ cord-005646-xhx9pzhj 1556 22 data datum NNS cord-005646-xhx9pzhj 1556 23 suggest suggest VBP cord-005646-xhx9pzhj 1556 24 that that IN cord-005646-xhx9pzhj 1556 25 compliance compliance NN cord-005646-xhx9pzhj 1556 26 measurements measurement NNS cord-005646-xhx9pzhj 1556 27 during during IN cord-005646-xhx9pzhj 1556 28 ECMO ECMO NNP cord-005646-xhx9pzhj 1556 29 can can MD cord-005646-xhx9pzhj 1556 30 be be VB cord-005646-xhx9pzhj 1556 31 useful useful JJ cord-005646-xhx9pzhj 1556 32 togelher togelher NN cord-005646-xhx9pzhj 1556 33 with with IN cord-005646-xhx9pzhj 1556 34 overall overall JJ cord-005646-xhx9pzhj 1556 35 clinical clinical JJ cord-005646-xhx9pzhj 1556 36 evaluation evaluation NN cord-005646-xhx9pzhj 1556 37 to to TO cord-005646-xhx9pzhj 1556 38 predict predict VB cord-005646-xhx9pzhj 1556 39 both both DT cord-005646-xhx9pzhj 1556 40 outcome outcome NN cord-005646-xhx9pzhj 1556 41 and and CC cord-005646-xhx9pzhj 1556 42 duration duration NN cord-005646-xhx9pzhj 1556 43 of of IN cord-005646-xhx9pzhj 1556 44 cxtracorporeaI cxtracorporeai JJ cord-005646-xhx9pzhj 1556 45 support support NN cord-005646-xhx9pzhj 1556 46 in in IN cord-005646-xhx9pzhj 1556 47 the the DT cord-005646-xhx9pzhj 1556 48 neonatal neonatal JJ cord-005646-xhx9pzhj 1556 49 and and CC cord-005646-xhx9pzhj 1556 50 pediatric pediatric JJ cord-005646-xhx9pzhj 1556 51 population population NN cord-005646-xhx9pzhj 1556 52 . . . cord-005646-xhx9pzhj 1557 1 Objectives objective NNS cord-005646-xhx9pzhj 1557 2 : : : cord-005646-xhx9pzhj 1558 1 Brain brain NN cord-005646-xhx9pzhj 1558 2 temperature temperature NN cord-005646-xhx9pzhj 1558 3 determines determine VBZ cord-005646-xhx9pzhj 1558 4 the the DT cord-005646-xhx9pzhj 1558 5 amount amount NN cord-005646-xhx9pzhj 1558 6 of of IN cord-005646-xhx9pzhj 1558 7 neuronal neuronal JJ cord-005646-xhx9pzhj 1558 8 damage damage NN cord-005646-xhx9pzhj 1558 9 caused cause VBN cord-005646-xhx9pzhj 1558 10 by by IN cord-005646-xhx9pzhj 1558 11 hypoxic hypoxic JJ cord-005646-xhx9pzhj 1558 12 insults insult NNS cord-005646-xhx9pzhj 1558 13 . . . cord-005646-xhx9pzhj 1559 1 Thus thus RB cord-005646-xhx9pzhj 1559 2 measuring measure VBG cord-005646-xhx9pzhj 1559 3 brain brain NN cord-005646-xhx9pzhj 1559 4 temperature temperature NN cord-005646-xhx9pzhj 1559 5 at at IN cord-005646-xhx9pzhj 1559 6 standardised standardised JJ cord-005646-xhx9pzhj 1559 7 conditions condition NNS cord-005646-xhx9pzhj 1559 8 is be VBZ cord-005646-xhx9pzhj 1559 9 in in IN cord-005646-xhx9pzhj 1559 10 request request NN cord-005646-xhx9pzhj 1559 11 . . . cord-005646-xhx9pzhj 1560 1 We -PRON- PRP cord-005646-xhx9pzhj 1560 2 investigated investigate VBD cord-005646-xhx9pzhj 1560 3 whether whether IN cord-005646-xhx9pzhj 1560 4 brain brain NN cord-005646-xhx9pzhj 1560 5 temperature temperature NN cord-005646-xhx9pzhj 1560 6 of of IN cord-005646-xhx9pzhj 1560 7 neonates neonate NNS cord-005646-xhx9pzhj 1560 8 varies vary VBZ cord-005646-xhx9pzhj 1560 9 with with IN cord-005646-xhx9pzhj 1560 10 head head NN cord-005646-xhx9pzhj 1560 11 insulation insulation NN cord-005646-xhx9pzhj 1560 12 environmental environmental JJ cord-005646-xhx9pzhj 1560 13 temperature temperature NN cord-005646-xhx9pzhj 1560 14 , , , cord-005646-xhx9pzhj 1560 15 body body NN cord-005646-xhx9pzhj 1560 16 activity activity NN cord-005646-xhx9pzhj 1560 17 and and CC cord-005646-xhx9pzhj 1560 18 time time NN cord-005646-xhx9pzhj 1560 19 course course NN cord-005646-xhx9pzhj 1560 20 . . . cord-005646-xhx9pzhj 1561 1 Patients patient NNS cord-005646-xhx9pzhj 1561 2 and and CC cord-005646-xhx9pzhj 1561 3 Methods method NNS cord-005646-xhx9pzhj 1562 1 : : : cord-005646-xhx9pzhj 1562 2 We -PRON- PRP cord-005646-xhx9pzhj 1562 3 investigated investigate VBD cord-005646-xhx9pzhj 1562 4 non non JJ cord-005646-xhx9pzhj 1562 5 - - JJ cord-005646-xhx9pzhj 1562 6 invasive invasive JJ cord-005646-xhx9pzhj 1562 7 brain brain NN cord-005646-xhx9pzhj 1562 8 temperature temperature NN cord-005646-xhx9pzhj 1562 9 analogues analogue NNS cord-005646-xhx9pzhj 1562 10 in in IN cord-005646-xhx9pzhj 1562 11 19 19 CD cord-005646-xhx9pzhj 1562 12 healthy healthy JJ cord-005646-xhx9pzhj 1562 13 prematures premature NNS cord-005646-xhx9pzhj 1562 14 tess tess NNP cord-005646-xhx9pzhj 1562 15 than than IN cord-005646-xhx9pzhj 1562 16 two two CD cord-005646-xhx9pzhj 1562 17 weeks week NNS cord-005646-xhx9pzhj 1562 18 of of IN cord-005646-xhx9pzhj 1562 19 age age NN cord-005646-xhx9pzhj 1562 20 in in IN cord-005646-xhx9pzhj 1562 21 an an DT cord-005646-xhx9pzhj 1562 22 incubator incubator NN cord-005646-xhx9pzhj 1562 23 ( ( -LRB- cord-005646-xhx9pzhj 1562 24 gestational gestational JJ cord-005646-xhx9pzhj 1562 25 age age NN cord-005646-xhx9pzhj 1562 26 31.5 31.5 CD cord-005646-xhx9pzhj 1562 27 + + SYM cord-005646-xhx9pzhj 1562 28 2.1 2.1 CD cord-005646-xhx9pzhj 1562 29 wks wks NN cord-005646-xhx9pzhj 1562 30 ; ; . cord-005646-xhx9pzhj 1563 1 x x LS cord-005646-xhx9pzhj 1563 2 + + CC cord-005646-xhx9pzhj 1563 3 SD sd NN cord-005646-xhx9pzhj 1563 4 , , , cord-005646-xhx9pzhj 1563 5 weight weight NN cord-005646-xhx9pzhj 1563 6 1653 1653 CD cord-005646-xhx9pzhj 1563 7 + + SYM cord-005646-xhx9pzhj 1563 8 370 370 CD cord-005646-xhx9pzhj 1563 9 g g NN cord-005646-xhx9pzhj 1563 10 ) ) -RRB- cord-005646-xhx9pzhj 1563 11 . . . cord-005646-xhx9pzhj 1564 1 We -PRON- PRP cord-005646-xhx9pzhj 1564 2 measured measure VBD cord-005646-xhx9pzhj 1564 3 nasopharyngeal nasopharyngeal JJ cord-005646-xhx9pzhj 1564 4 temperature temperature NN cord-005646-xhx9pzhj 1564 5 ( ( -LRB- cord-005646-xhx9pzhj 1564 6 Tnasoph Tnasoph NNP cord-005646-xhx9pzhj 1564 7 ) ) -RRB- cord-005646-xhx9pzhj 1564 8 by by IN cord-005646-xhx9pzhj 1564 9 a a DT cord-005646-xhx9pzhj 1564 10 thermistor thermistor NN cord-005646-xhx9pzhj 1564 11 placed place VBN cord-005646-xhx9pzhj 1564 12 in in IN cord-005646-xhx9pzhj 1564 13 the the DT cord-005646-xhx9pzhj 1564 14 nasopharynx nasopharynx NN cord-005646-xhx9pzhj 1564 15 via via IN cord-005646-xhx9pzhj 1564 16 a a DT cord-005646-xhx9pzhj 1564 17 feeding feeding NN cord-005646-xhx9pzhj 1564 18 tube tube NN cord-005646-xhx9pzhj 1564 19 , , , cord-005646-xhx9pzhj 1564 20 zero zero CD cord-005646-xhx9pzhj 1564 21 - - HYPH cord-005646-xhx9pzhj 1564 22 Heatflux Heatflux NNP cord-005646-xhx9pzhj 1564 23 Temperature Temperature NNP cord-005646-xhx9pzhj 1564 24 ( ( -LRB- cord-005646-xhx9pzhj 1564 25 zHT zHT NNP cord-005646-xhx9pzhj 1564 26 ) ) -RRB- cord-005646-xhx9pzhj 1564 27 at at IN cord-005646-xhx9pzhj 1564 28 the the DT cord-005646-xhx9pzhj 1564 29 temple temple NN cord-005646-xhx9pzhj 1564 30 by by IN cord-005646-xhx9pzhj 1564 31 a a DT cord-005646-xhx9pzhj 1564 32 thermistor thermistor NN cord-005646-xhx9pzhj 1564 33 and and CC cord-005646-xhx9pzhj 1564 34 healflux healflux NN cord-005646-xhx9pzhj 1564 35 transducer transducer NN cord-005646-xhx9pzhj 1564 36 , , , cord-005646-xhx9pzhj 1564 37 insulated insulate VBN cord-005646-xhx9pzhj 1564 38 by by IN cord-005646-xhx9pzhj 1564 39 two two CD cord-005646-xhx9pzhj 1564 40 pads pad NNS cord-005646-xhx9pzhj 1564 41 , , , cord-005646-xhx9pzhj 1564 42 as as RB cord-005646-xhx9pzhj 1564 43 well well RB cord-005646-xhx9pzhj 1564 44 as as IN cord-005646-xhx9pzhj 1564 45 rectal rectal JJ cord-005646-xhx9pzhj 1564 46 and and CC cord-005646-xhx9pzhj 1564 47 incubator incubator NN cord-005646-xhx9pzhj 1564 48 temperatures temperature NNS cord-005646-xhx9pzhj 1564 49 . . . cord-005646-xhx9pzhj 1565 1 Patient patient JJ cord-005646-xhx9pzhj 1565 2 activity activity NN cord-005646-xhx9pzhj 1565 3 was be VBD cord-005646-xhx9pzhj 1565 4 documented document VBN cord-005646-xhx9pzhj 1565 5 by by IN cord-005646-xhx9pzhj 1565 6 video video NN cord-005646-xhx9pzhj 1565 7 taping taping NN cord-005646-xhx9pzhj 1565 8 . . . cord-005646-xhx9pzhj 1566 1 Measurements measurement NNS cord-005646-xhx9pzhj 1566 2 were be VBD cord-005646-xhx9pzhj 1566 3 performed perform VBN cord-005646-xhx9pzhj 1566 4 during during IN cord-005646-xhx9pzhj 1566 5 periods period NNS cord-005646-xhx9pzhj 1566 6 of of IN cord-005646-xhx9pzhj 1566 7 increased increase VBN cord-005646-xhx9pzhj 1566 8 insulation insulation NN cord-005646-xhx9pzhj 1566 9 1 1 CD cord-005646-xhx9pzhj 1566 10 ) ) -RRB- cord-005646-xhx9pzhj 1566 11 by by IN cord-005646-xhx9pzhj 1566 12 turning turn VBG cord-005646-xhx9pzhj 1566 13 the the DT cord-005646-xhx9pzhj 1566 14 head head NN cord-005646-xhx9pzhj 1566 15 with with IN cord-005646-xhx9pzhj 1566 16 its -PRON- PRP$ cord-005646-xhx9pzhj 1566 17 measuring measure VBG cord-005646-xhx9pzhj 1566 18 site site NN cord-005646-xhx9pzhj 1566 19 on on IN cord-005646-xhx9pzhj 1566 20 to to IN cord-005646-xhx9pzhj 1566 21 the the DT cord-005646-xhx9pzhj 1566 22 mattress mattress NN cord-005646-xhx9pzhj 1566 23 ( ( -LRB- cord-005646-xhx9pzhj 1566 24 ( ( -LRB- cord-005646-xhx9pzhj 1566 25 5 5 LS cord-005646-xhx9pzhj 1566 26 ) ) -RRB- cord-005646-xhx9pzhj 1566 27 3 3 CD cord-005646-xhx9pzhj 1566 28 ( ( -LRB- cord-005646-xhx9pzhj 1566 29 5 5 CD cord-005646-xhx9pzhj 1566 30 ) ) -RRB- cord-005646-xhx9pzhj 1566 31 -2 -2 CD cord-005646-xhx9pzhj 1566 32 ( ( -LRB- cord-005646-xhx9pzhj 1566 33 6 6 CD cord-005646-xhx9pzhj 1566 34 ) ) -RRB- cord-005646-xhx9pzhj 1566 35 4 4 CD cord-005646-xhx9pzhj 1566 36 ( ( -LRB- cord-005646-xhx9pzhj 1566 37 5 5 CD cord-005646-xhx9pzhj 1566 38 ) ) -RRB- cord-005646-xhx9pzhj 1566 39 0 0 NFP cord-005646-xhx9pzhj 1566 40 ( ( -LRB- cord-005646-xhx9pzhj 1566 41 6 6 CD cord-005646-xhx9pzhj 1566 42 ) ) -RRB- cord-005646-xhx9pzhj 1566 43 4 4 CD cord-005646-xhx9pzhj 1566 44 ( ( -LRB- cord-005646-xhx9pzhj 1566 45 3 3 CD cord-005646-xhx9pzhj 1566 46 ) ) -RRB- cord-005646-xhx9pzhj 1566 47 2.5 2.5 CD cord-005646-xhx9pzhj 1566 48 2 2 CD cord-005646-xhx9pzhj 1566 49 4(5 4(5 NNP cord-005646-xhx9pzhj 1566 50 ) ) -RRB- cord-005646-xhx9pzhj 1566 51 25(10 25(10 CD cord-005646-xhx9pzhj 1566 52 ) ) -RRB- cord-005646-xhx9pzhj 1566 53 20{12 20{12 CD cord-005646-xhx9pzhj 1566 54 ) ) -RRB- cord-005646-xhx9pzhj 1566 55 8(5 8(5 CD cord-005646-xhx9pzhj 1566 56 ) ) -RRB- cord-005646-xhx9pzhj 1566 57 5(10 5(10 CD cord-005646-xhx9pzhj 1566 58 ) ) -RRB- cord-005646-xhx9pzhj 1566 59 -2(7 -2(7 NNP cord-005646-xhx9pzhj 1566 60 ) ) -RRB- cord-005646-xhx9pzhj 1567 1 5 5 CD cord-005646-xhx9pzhj 1567 2 6 6 CD cord-005646-xhx9pzhj 1567 3 38 38 CD cord-005646-xhx9pzhj 1567 4 ( ( -LRB- cord-005646-xhx9pzhj 1567 5 22 22 CD cord-005646-xhx9pzhj 1567 6 ) ) -RRB- cord-005646-xhx9pzhj 1568 1 112(34)I70 112(34)i70 CD cord-005646-xhx9pzhj 1568 2 ( ( -LRB- cord-005646-xhx9pzhj 1568 3 48)51(27 48)51(27 CD cord-005646-xhx9pzhj 1568 4 ) ) -RRB- cord-005646-xhx9pzhj 1568 5 20 20 CD cord-005646-xhx9pzhj 1568 6 ( ( -LRB- cord-005646-xhx9pzhj 1568 7 18 18 CD cord-005646-xhx9pzhj 1568 8 ) ) -RRB- cord-005646-xhx9pzhj 1568 9 5(15 5(15 CD cord-005646-xhx9pzhj 1568 10 ) ) -RRB- cord-005646-xhx9pzhj 1569 1 7.5 7.5 CD cord-005646-xhx9pzhj 1569 2 3 3 CD cord-005646-xhx9pzhj 1569 3 38 38 CD cord-005646-xhx9pzhj 1569 4 ( ( -LRB- cord-005646-xhx9pzhj 1569 5 19 19 CD cord-005646-xhx9pzhj 1569 6 ) ) -RRB- cord-005646-xhx9pzhj 1570 1 125(21 125(21 LS cord-005646-xhx9pzhj 1570 2 ) ) -RRB- cord-005646-xhx9pzhj 1570 3 t85(29 t85(29 NN cord-005646-xhx9pzhj 1570 4 ) ) -RRB- cord-005646-xhx9pzhj 1571 1 120(30 120(30 LS cord-005646-xhx9pzhj 1571 2 ) ) -RRB- cord-005646-xhx9pzhj 1571 3 70(30 70(30 CD cord-005646-xhx9pzhj 1571 4 ) ) -RRB- cord-005646-xhx9pzhj 1571 5 30(20 30(20 CD cord-005646-xhx9pzhj 1571 6 ) ) -RRB- cord-005646-xhx9pzhj 1571 7 10 10 CD cord-005646-xhx9pzhj 1571 8 4 4 CD cord-005646-xhx9pzhj 1571 9 53 53 CD cord-005646-xhx9pzhj 1571 10 ( ( -LRB- cord-005646-xhx9pzhj 1571 11 30 30 CD cord-005646-xhx9pzhj 1571 12 ) ) -RRB- cord-005646-xhx9pzhj 1572 1 133(28 133(28 LS cord-005646-xhx9pzhj 1572 2 ) ) -RRB- cord-005646-xhx9pzhj 1573 1 182(33 182(33 LS cord-005646-xhx9pzhj 1573 2 ) ) -RRB- cord-005646-xhx9pzhj 1573 3 157(24 157(24 CD cord-005646-xhx9pzhj 1573 4 ) ) -RRB- cord-005646-xhx9pzhj 1574 1 154(34 154(34 CD cord-005646-xhx9pzhj 1574 2 ) ) -RRB- cord-005646-xhx9pzhj 1575 1 110(45 110(45 LS cord-005646-xhx9pzhj 1575 2 ) ) -RRB- cord-005646-xhx9pzhj 1576 1 WEB web NN cord-005646-xhx9pzhj 1576 2 2170 2170 CD cord-005646-xhx9pzhj 1577 1 ( ( -LRB- cord-005646-xhx9pzhj 1577 2 lmg lmg NNP cord-005646-xhx9pzhj 1577 3 / / SYM cord-005646-xhx9pzhj 1577 4 Kg Kg NNP cord-005646-xhx9pzhj 1577 5 ) ) -RRB- cord-005646-xhx9pzhj 1577 6 5 5 CD cord-005646-xhx9pzhj 1577 7 at at IN cord-005646-xhx9pzhj 1577 8 30 30 CD cord-005646-xhx9pzhj 1577 9 rain rain NN cord-005646-xhx9pzhj 1577 10 3 3 CD cord-005646-xhx9pzhj 1577 11 3 3 CD cord-005646-xhx9pzhj 1577 12 ( ( -LRB- cord-005646-xhx9pzhj 1577 13 5 5 CD cord-005646-xhx9pzhj 1577 14 ) ) -RRB- cord-005646-xhx9pzhj 1577 15 -4 -4 . cord-005646-xhx9pzhj 1578 1 ( ( -LRB- cord-005646-xhx9pzhj 1578 2 6 6 CD cord-005646-xhx9pzhj 1578 3 ) ) -RRB- cord-005646-xhx9pzhj 1578 4 5 5 CD cord-005646-xhx9pzhj 1578 5 ( ( -LRB- cord-005646-xhx9pzhj 1578 6 6 6 CD cord-005646-xhx9pzhj 1578 7 ) ) -RRB- cord-005646-xhx9pzhj 1578 8 4 4 CD cord-005646-xhx9pzhj 1578 9 ( ( -LRB- cord-005646-xhx9pzhj 1578 10 3 3 CD cord-005646-xhx9pzhj 1578 11 ) ) -RRB- cord-005646-xhx9pzhj 1578 12 5 5 CD cord-005646-xhx9pzhj 1578 13 ( ( -LRB- cord-005646-xhx9pzhj 1578 14 4 4 CD cord-005646-xhx9pzhj 1578 15 ) ) -RRB- cord-005646-xhx9pzhj 1578 16 -3 -3 . cord-005646-xhx9pzhj 1579 1 ( ( -LRB- cord-005646-xhx9pzhj 1579 2 6 6 CD cord-005646-xhx9pzhj 1579 3 ) ) -RRB- cord-005646-xhx9pzhj 1580 1 The the DT cord-005646-xhx9pzhj 1580 2 vehicle vehicle NN cord-005646-xhx9pzhj 1580 3 had have VBD cord-005646-xhx9pzhj 1580 4 no no DT cord-005646-xhx9pzhj 1580 5 effect effect NN cord-005646-xhx9pzhj 1580 6 . . . cord-005646-xhx9pzhj 1581 1 PAF PAF NNP cord-005646-xhx9pzhj 1581 2 caused cause VBD cord-005646-xhx9pzhj 1581 3 dose dose NN cord-005646-xhx9pzhj 1581 4 dependent dependent JJ cord-005646-xhx9pzhj 1581 5 rise rise NN cord-005646-xhx9pzhj 1581 6 in in IN cord-005646-xhx9pzhj 1581 7 AO AO NNP cord-005646-xhx9pzhj 1581 8 and and CC cord-005646-xhx9pzhj 1581 9 PA PA NNP cord-005646-xhx9pzhj 1581 10 pressure pressure NN cord-005646-xhx9pzhj 1581 11 and and CC cord-005646-xhx9pzhj 1581 12 reduction reduction NN cord-005646-xhx9pzhj 1581 13 in in IN cord-005646-xhx9pzhj 1581 14 flow flow NN cord-005646-xhx9pzhj 1581 15 to to IN cord-005646-xhx9pzhj 1581 16 LPA LPA NNP cord-005646-xhx9pzhj 1581 17 ( ( -LRB- cord-005646-xhx9pzhj 1581 18 up up IN cord-005646-xhx9pzhj 1581 19 to to TO cord-005646-xhx9pzhj 1581 20 80 80 CD cord-005646-xhx9pzhj 1581 21 % % NN cord-005646-xhx9pzhj 1582 1 Like like IN cord-005646-xhx9pzhj 1582 2 the the DT cord-005646-xhx9pzhj 1582 3 vascular vascular JJ cord-005646-xhx9pzhj 1582 4 endothelium endothelium NN cord-005646-xhx9pzhj 1582 5 , , , cord-005646-xhx9pzhj 1582 6 the the DT cord-005646-xhx9pzhj 1582 7 endocardial endocardial JJ cord-005646-xhx9pzhj 1582 8 endothelium endothelium NN cord-005646-xhx9pzhj 1582 9 ( ( -LRB- cord-005646-xhx9pzhj 1582 10 EE EE NNP cord-005646-xhx9pzhj 1582 11 ) ) -RRB- cord-005646-xhx9pzhj 1582 12 has have VBZ cord-005646-xhx9pzhj 1582 13 a a DT cord-005646-xhx9pzhj 1582 14 significant significant JJ cord-005646-xhx9pzhj 1582 15 impact impact NN cord-005646-xhx9pzhj 1582 16 on on IN cord-005646-xhx9pzhj 1582 17 adjacent adjacent JJ cord-005646-xhx9pzhj 1582 18 myocytes myocyte NNS cord-005646-xhx9pzhj 1582 19 , , , cord-005646-xhx9pzhj 1582 20 and and CC cord-005646-xhx9pzhj 1582 21 may may MD cord-005646-xhx9pzhj 1582 22 critically critically RB cord-005646-xhx9pzhj 1582 23 alter alter VB cord-005646-xhx9pzhj 1582 24 myocardial myocardial NN cord-005646-xhx9pzhj 1583 1 function.~ function.~ VBN cord-005646-xhx9pzhj 1584 1 We -PRON- PRP cord-005646-xhx9pzhj 1584 2 have have VBP cord-005646-xhx9pzhj 1584 3 previously previously RB cord-005646-xhx9pzhj 1584 4 shown show VBN cord-005646-xhx9pzhj 1584 5 that that IN cord-005646-xhx9pzhj 1584 6 EE EE NNP cord-005646-xhx9pzhj 1584 7 cells cell NNS cord-005646-xhx9pzhj 1584 8 are be VBP cord-005646-xhx9pzhj 1584 9 capable capable JJ cord-005646-xhx9pzhj 1584 10 of of IN cord-005646-xhx9pzhj 1584 11 sensing sense VBG cord-005646-xhx9pzhj 1584 12 and and CC cord-005646-xhx9pzhj 1584 13 responding respond VBG cord-005646-xhx9pzhj 1584 14 to to IN cord-005646-xhx9pzhj 1584 15 hypoxia hypoxia NN cord-005646-xhx9pzhj 1584 16 by by IN cord-005646-xhx9pzhj 1584 17 the the DT cord-005646-xhx9pzhj 1584 18 release release NN cord-005646-xhx9pzhj 1584 19 of of IN cord-005646-xhx9pzhj 1584 20 prostacyclin prostacyclin NNP cord-005646-xhx9pzhj 1584 21 ( ( -LRB- cord-005646-xhx9pzhj 1584 22 PGL PGL NNP cord-005646-xhx9pzhj 1584 23 ) ) -RRB- cord-005646-xhx9pzhj 1584 24 . . . cord-005646-xhx9pzhj 1585 1 2 2 CD cord-005646-xhx9pzhj 1585 2 Potassium potassium NN cord-005646-xhx9pzhj 1585 3 channels channel NNS cord-005646-xhx9pzhj 1585 4 in in IN cord-005646-xhx9pzhj 1585 5 other other JJ cord-005646-xhx9pzhj 1585 6 cell cell NN cord-005646-xhx9pzhj 1585 7 types type NNS cord-005646-xhx9pzhj 1585 8 have have VBP cord-005646-xhx9pzhj 1585 9 been be VBN cord-005646-xhx9pzhj 1585 10 reported report VBN cord-005646-xhx9pzhj 1585 11 to to TO cord-005646-xhx9pzhj 1585 12 be be VB cord-005646-xhx9pzhj 1585 13 oxygen oxygen NN cord-005646-xhx9pzhj 1585 14 sensitive sensitive JJ cord-005646-xhx9pzhj 1585 15 . . . cord-005646-xhx9pzhj 1586 1 To to TO cord-005646-xhx9pzhj 1586 2 determine determine VB cord-005646-xhx9pzhj 1586 3 whether whether IN cord-005646-xhx9pzhj 1586 4 potassium potassium NN cord-005646-xhx9pzhj 1586 5 channels channel NNS cord-005646-xhx9pzhj 1586 6 modulate modulate VBP cord-005646-xhx9pzhj 1586 7 the the DT cord-005646-xhx9pzhj 1586 8 EE EE NNP cord-005646-xhx9pzhj 1586 9 hypoxic hypoxic JJ cord-005646-xhx9pzhj 1586 10 response response NN cord-005646-xhx9pzhj 1586 11 , , , cord-005646-xhx9pzhj 1586 12 we -PRON- PRP cord-005646-xhx9pzhj 1586 13 investigated investigate VBD cord-005646-xhx9pzhj 1586 14 the the DT cord-005646-xhx9pzhj 1586 15 effects effect NNS cord-005646-xhx9pzhj 1586 16 of of IN cord-005646-xhx9pzhj 1586 17 three three CD cord-005646-xhx9pzhj 1586 18 potassium potassium NN cord-005646-xhx9pzhj 1586 19 channel channel NN cord-005646-xhx9pzhj 1586 20 inhibitors inhibitor NNS cord-005646-xhx9pzhj 1586 21 on on IN cord-005646-xhx9pzhj 1586 22 hypoxia hypoxia NN cord-005646-xhx9pzhj 1586 23 - - HYPH cord-005646-xhx9pzhj 1586 24 induced induce VBN cord-005646-xhx9pzhj 1586 25 PG PG NNP cord-005646-xhx9pzhj 1586 26 ] ] -RRB- cord-005646-xhx9pzhj 1586 27 2 2 CD cord-005646-xhx9pzhj 1586 28 release release NN cord-005646-xhx9pzhj 1586 29 from from IN cord-005646-xhx9pzhj 1586 30 EE EE NNP cord-005646-xhx9pzhj 1586 31 cells cell NNS cord-005646-xhx9pzhj 1586 32 . . . cord-005646-xhx9pzhj 1587 1 Methods method NNS cord-005646-xhx9pzhj 1587 2 : : : cord-005646-xhx9pzhj 1587 3 Ovine ovine JJ cord-005646-xhx9pzhj 1587 4 endothelial endothelial JJ cord-005646-xhx9pzhj 1587 5 cells cell NNS cord-005646-xhx9pzhj 1587 6 were be VBD cord-005646-xhx9pzhj 1587 7 harvested harvest VBN cord-005646-xhx9pzhj 1587 8 and and CC cord-005646-xhx9pzhj 1587 9 passaged passage VBN cord-005646-xhx9pzhj 1587 10 onto onto IN cord-005646-xhx9pzhj 1587 11 30 30 CD cord-005646-xhx9pzhj 1587 12 , , , cord-005646-xhx9pzhj 1587 13 ~ ~ CD cord-005646-xhx9pzhj 1587 14 microcarriers microcarrier NNS cord-005646-xhx9pzhj 1587 15 . . . cord-005646-xhx9pzhj 1588 1 Cells cell NNS cord-005646-xhx9pzhj 1588 2 were be VBD cord-005646-xhx9pzhj 1588 3 constantly constantly RB cord-005646-xhx9pzhj 1588 4 perfused perfuse VBN cord-005646-xhx9pzhj 1588 5 with with IN cord-005646-xhx9pzhj 1588 6 normoxic normoxic JJ cord-005646-xhx9pzhj 1588 7 and and CC cord-005646-xhx9pzhj 1588 8 hypoxic hypoxic JJ cord-005646-xhx9pzhj 1588 9 Kreb Kreb NNP cord-005646-xhx9pzhj 1588 10 's 's POS cord-005646-xhx9pzhj 1588 11 solution solution NN cord-005646-xhx9pzhj 1588 12 , , , cord-005646-xhx9pzhj 1588 13 and and CC cord-005646-xhx9pzhj 1588 14 with with IN cord-005646-xhx9pzhj 1588 15 three three CD cord-005646-xhx9pzhj 1588 16 potassium potassium NN cord-005646-xhx9pzhj 1588 17 channel channel NN cord-005646-xhx9pzhj 1588 18 blockers blocker NNS cord-005646-xhx9pzhj 1588 19 : : : cord-005646-xhx9pzhj 1588 20 glibenclamide glibenclamide NNP cord-005646-xhx9pzhj 1588 21 ( ( -LRB- cord-005646-xhx9pzhj 1588 22 GB GB NNP cord-005646-xhx9pzhj 1588 23 , , , cord-005646-xhx9pzhj 1588 24 3 3 CD cord-005646-xhx9pzhj 1588 25 # # NN cord-005646-xhx9pzhj 1588 26 g g NN cord-005646-xhx9pzhj 1588 27 / / SYM cord-005646-xhx9pzhj 1588 28 ml ml NN cord-005646-xhx9pzhj 1588 29 ) ) -RRB- cord-005646-xhx9pzhj 1588 30 , , , cord-005646-xhx9pzhj 1588 31 tetraethyl tetraethyl NN cord-005646-xhx9pzhj 1588 32 - - HYPH cord-005646-xhx9pzhj 1588 33 antmonium antmonium NN cord-005646-xhx9pzhj 1588 34 ( ( -LRB- cord-005646-xhx9pzhj 1588 35 TEA tea NN cord-005646-xhx9pzhj 1588 36 , , , cord-005646-xhx9pzhj 1588 37 10 10 CD cord-005646-xhx9pzhj 1588 38 raM ram NN cord-005646-xhx9pzhj 1588 39 ) ) -RRB- cord-005646-xhx9pzhj 1588 40 and and CC cord-005646-xhx9pzhj 1588 41 4 4 CD cord-005646-xhx9pzhj 1588 42 aminopyridine aminopyridine JJ cord-005646-xhx9pzhj 1588 43 ( ( -LRB- cord-005646-xhx9pzhj 1588 44 4AP 4ap CD cord-005646-xhx9pzhj 1588 45 , , , cord-005646-xhx9pzhj 1588 46 I0 I0 NNP cord-005646-xhx9pzhj 1588 47 mM mM NNP cord-005646-xhx9pzhj 1588 48 ) ) -RRB- cord-005646-xhx9pzhj 1588 49 , , , cord-005646-xhx9pzhj 1588 50 Perfusate Perfusate NNP cord-005646-xhx9pzhj 1588 51 was be VBD cord-005646-xhx9pzhj 1588 52 assayed assay VBN cord-005646-xhx9pzhj 1588 53 for for IN cord-005646-xhx9pzhj 1588 54 prostacyclin prostacyclin NNP cord-005646-xhx9pzhj 1588 55 ( ( -LRB- cord-005646-xhx9pzhj 1588 56 RIA RIA NNP cord-005646-xhx9pzhj 1588 57 ) ) -RRB- cord-005646-xhx9pzhj 1588 58 . . . cord-005646-xhx9pzhj 1589 1 Data datum NNS cord-005646-xhx9pzhj 1589 2 were be VBD cord-005646-xhx9pzhj 1589 3 compared compare VBN cord-005646-xhx9pzhj 1589 4 by by IN cord-005646-xhx9pzhj 1589 5 analysis analysis NN cord-005646-xhx9pzhj 1589 6 of of IN cord-005646-xhx9pzhj 1589 7 variance variance NN cord-005646-xhx9pzhj 1589 8 . . . cord-005646-xhx9pzhj 1590 1 * * NFP cord-005646-xhx9pzhj 1591 1 p<.05 p<.05 JJ cord-005646-xhx9pzhj 1592 1 compared compare VBN cord-005646-xhx9pzhj 1592 2 to to IN cord-005646-xhx9pzhj 1592 3 3normoxic 3normoxic CD cord-005646-xhx9pzhj 1592 4 control control NN cord-005646-xhx9pzhj 1592 5 ; ; : cord-005646-xhx9pzhj 1592 6 # # NN cord-005646-xhx9pzhj 1592 7 p p NN cord-005646-xhx9pzhj 1592 8 < < XX cord-005646-xhx9pzhj 1592 9 .05 .05 NNS cord-005646-xhx9pzhj 1592 10 compared compare VBN cord-005646-xhx9pzhj 1592 11 to to IN cord-005646-xhx9pzhj 1592 12 hypoxic hypoxic JJ cord-005646-xhx9pzhj 1592 13 control control NN cord-005646-xhx9pzhj 1592 14 . . . cord-005646-xhx9pzhj 1593 1 Adrenaline adrenaline NN cord-005646-xhx9pzhj 1593 2 is be VBZ cord-005646-xhx9pzhj 1593 3 extensively extensively RB cord-005646-xhx9pzhj 1593 4 used use VBN cord-005646-xhx9pzhj 1593 5 for for IN cord-005646-xhx9pzhj 1593 6 resuscitation resuscitation NN cord-005646-xhx9pzhj 1593 7 in in IN cord-005646-xhx9pzhj 1593 8 neonates neonate NNS cord-005646-xhx9pzhj 1593 9 with with IN cord-005646-xhx9pzhj 1593 10 RDS RDS NNP cord-005646-xhx9pzhj 1593 11 . . . cord-005646-xhx9pzhj 1594 1 However however RB cord-005646-xhx9pzhj 1594 2 , , , cord-005646-xhx9pzhj 1594 3 effects effect NNS cord-005646-xhx9pzhj 1594 4 of of IN cord-005646-xhx9pzhj 1594 5 adrenaline adrenaline NN cord-005646-xhx9pzhj 1594 6 on on IN cord-005646-xhx9pzhj 1594 7 systemic systemic JJ cord-005646-xhx9pzhj 1594 8 , , , cord-005646-xhx9pzhj 1594 9 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1594 10 and and CC cord-005646-xhx9pzhj 1594 11 cerebral cerebral JJ cord-005646-xhx9pzhj 1594 12 hemodynamics hemodynamic NNS cord-005646-xhx9pzhj 1594 13 have have VBP cord-005646-xhx9pzhj 1594 14 not not RB cord-005646-xhx9pzhj 1594 15 been be VBN cord-005646-xhx9pzhj 1594 16 defined define VBN cord-005646-xhx9pzhj 1594 17 in in IN cord-005646-xhx9pzhj 1594 18 newborns newborn NNS cord-005646-xhx9pzhj 1594 19 with with IN cord-005646-xhx9pzhj 1594 20 RDS RDS NNP cord-005646-xhx9pzhj 1594 21 . . . cord-005646-xhx9pzhj 1595 1 Thirteen thirteen CD cord-005646-xhx9pzhj 1595 2 anesthetized anesthetize VBN cord-005646-xhx9pzhj 1595 3 , , , cord-005646-xhx9pzhj 1595 4 and and CC cord-005646-xhx9pzhj 1595 5 ventilated ventilate VBN cord-005646-xhx9pzhj 1595 6 newborn newborn JJ cord-005646-xhx9pzhj 1595 7 piglets piglet NNS cord-005646-xhx9pzhj 1595 8 were be VBD cord-005646-xhx9pzhj 1595 9 subjected subject VBN cord-005646-xhx9pzhj 1595 10 to to IN cord-005646-xhx9pzhj 1595 11 repeated repeat VBN cord-005646-xhx9pzhj 1595 12 saline saline NN cord-005646-xhx9pzhj 1595 13 lung lung NN cord-005646-xhx9pzhj 1595 14 - - HYPH cord-005646-xhx9pzhj 1595 15 lavage lavage NN cord-005646-xhx9pzhj 1595 16 series series NN cord-005646-xhx9pzhj 1595 17 while while IN cord-005646-xhx9pzhj 1595 18 mean mean VBP cord-005646-xhx9pzhj 1595 19 systemic systemic JJ cord-005646-xhx9pzhj 1595 20 arterial arterial JJ cord-005646-xhx9pzhj 1595 21 pressure pressure NN cord-005646-xhx9pzhj 1595 22 ( ( -LRB- cord-005646-xhx9pzhj 1595 23 ABP ABP NNP cord-005646-xhx9pzhj 1595 24 ) ) -RRB- cord-005646-xhx9pzhj 1596 1 , , , cord-005646-xhx9pzhj 1596 2 mean mean VB cord-005646-xhx9pzhj 1596 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1596 4 arteriat arteriat NN cord-005646-xhx9pzhj 1596 5 pressure pressure NN cord-005646-xhx9pzhj 1596 6 ( ( -LRB- cord-005646-xhx9pzhj 1596 7 PAP PAP NNP cord-005646-xhx9pzhj 1596 8 ) ) -RRB- cord-005646-xhx9pzhj 1596 9 , , , cord-005646-xhx9pzhj 1596 10 mean mean VB cord-005646-xhx9pzhj 1596 11 left left JJ cord-005646-xhx9pzhj 1596 12 atrial atrial JJ cord-005646-xhx9pzhj 1596 13 pressure pressure NN cord-005646-xhx9pzhj 1596 14 ( ( -LRB- cord-005646-xhx9pzhj 1596 15 LAP lap NN cord-005646-xhx9pzhj 1596 16 ) ) -RRB- cord-005646-xhx9pzhj 1596 17 and and CC cord-005646-xhx9pzhj 1596 18 mean mean VB cord-005646-xhx9pzhj 1596 19 central central JJ cord-005646-xhx9pzhj 1596 20 venous venous JJ cord-005646-xhx9pzhj 1596 21 pressure pressure NN cord-005646-xhx9pzhj 1596 22 ( ( -LRB- cord-005646-xhx9pzhj 1596 23 CVP CVP NNP cord-005646-xhx9pzhj 1596 24 ) ) -RRB- cord-005646-xhx9pzhj 1596 25 , , , cord-005646-xhx9pzhj 1596 26 cardiac cardiac JJ cord-005646-xhx9pzhj 1596 27 output output NN cord-005646-xhx9pzhj 1596 28 and and CC cord-005646-xhx9pzhj 1596 29 blood blood NN cord-005646-xhx9pzhj 1596 30 flow flow NN cord-005646-xhx9pzhj 1596 31 in in IN cord-005646-xhx9pzhj 1596 32 the the DT cord-005646-xhx9pzhj 1596 33 internal internal JJ cord-005646-xhx9pzhj 1596 34 carotid carotid JJ cord-005646-xhx9pzhj 1596 35 artery artery NN cord-005646-xhx9pzhj 1596 36 ( ( -LRB- cord-005646-xhx9pzhj 1596 37 ICA ICA NNP cord-005646-xhx9pzhj 1596 38 ) ) -RRB- cord-005646-xhx9pzhj 1596 39 were be VBD cord-005646-xhx9pzhj 1596 40 measured measure VBN cord-005646-xhx9pzhj 1596 41 . . . cord-005646-xhx9pzhj 1597 1 Systemic systemic JJ cord-005646-xhx9pzhj 1597 2 vascular vascular JJ cord-005646-xhx9pzhj 1597 3 resistance resistance NN cord-005646-xhx9pzhj 1597 4 ( ( -LRB- cord-005646-xhx9pzhj 1597 5 S~ S~ NNP cord-005646-xhx9pzhj 1597 6 ) ) -RRB- cord-005646-xhx9pzhj 1597 7 , , , cord-005646-xhx9pzhj 1597 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1597 9 vascular vascular JJ cord-005646-xhx9pzhj 1597 10 resistance resistance NN cord-005646-xhx9pzhj 1597 11 ( ( -LRB- cord-005646-xhx9pzhj 1597 12 PVR PVR NNP cord-005646-xhx9pzhj 1597 13 ) ) -RRB- cord-005646-xhx9pzhj 1597 14 and and CC cord-005646-xhx9pzhj 1597 15 cardiac cardiac JJ cord-005646-xhx9pzhj 1597 16 index index NN cord-005646-xhx9pzhj 1597 17 ( ( -LRB- cord-005646-xhx9pzhj 1597 18 CI CI NNP cord-005646-xhx9pzhj 1597 19 ) ) -RRB- cord-005646-xhx9pzhj 1597 20 were be VBD cord-005646-xhx9pzhj 1597 21 calculated calculate VBN cord-005646-xhx9pzhj 1597 22 . . . cord-005646-xhx9pzhj 1598 1 Sixty sixty CD cord-005646-xhx9pzhj 1598 2 minutes minute NNS cord-005646-xhx9pzhj 1598 3 after after IN cord-005646-xhx9pzhj 1598 4 luug luug NN cord-005646-xhx9pzhj 1598 5 - - HYPH cord-005646-xhx9pzhj 1598 6 lavage lavage NN cord-005646-xhx9pzhj 1598 7 , , , cord-005646-xhx9pzhj 1598 8 the the DT cord-005646-xhx9pzhj 1598 9 adrenaline adrenaline NN cord-005646-xhx9pzhj 1598 10 group group NN cord-005646-xhx9pzhj 1598 11 ( ( -LRB- cord-005646-xhx9pzhj 1598 12 A a NN cord-005646-xhx9pzhj 1598 13 ) ) -RRB- cord-005646-xhx9pzhj 1598 14 ( ( -LRB- cord-005646-xhx9pzhj 1598 15 n=6 n=6 NNP cord-005646-xhx9pzhj 1598 16 ) ) -RRB- cord-005646-xhx9pzhj 1598 17 received receive VBN cord-005646-xhx9pzhj 1598 18 adrenaline adrenaline NN cord-005646-xhx9pzhj 1598 19 as as IN cord-005646-xhx9pzhj 1598 20 a a DT cord-005646-xhx9pzhj 1598 21 continuous continuous JJ cord-005646-xhx9pzhj 1598 22 infusion infusion NN cord-005646-xhx9pzhj 1598 23 of of IN cord-005646-xhx9pzhj 1598 24 1.2 1.2 CD cord-005646-xhx9pzhj 1598 25 lag lag NNS cord-005646-xhx9pzhj 1598 26 / / SYM cord-005646-xhx9pzhj 1598 27 kg kg NNP cord-005646-xhx9pzhj 1598 28 / / SYM cord-005646-xhx9pzhj 1598 29 mi mi NNP cord-005646-xhx9pzhj 1598 30 , , , cord-005646-xhx9pzhj 1598 31 while while IN cord-005646-xhx9pzhj 1598 32 the the DT cord-005646-xhx9pzhj 1598 33 control control NN cord-005646-xhx9pzhj 1598 34 group group NN cord-005646-xhx9pzhj 1598 35 ( ( -LRB- cord-005646-xhx9pzhj 1598 36 C C NNP cord-005646-xhx9pzhj 1598 37 ) ) -RRB- cord-005646-xhx9pzhj 1598 38 ( ( -LRB- cord-005646-xhx9pzhj 1598 39 n=7 n=7 NN cord-005646-xhx9pzhj 1598 40 ) ) -RRB- cord-005646-xhx9pzhj 1598 41 received receive VBD cord-005646-xhx9pzhj 1598 42 saline saline NN cord-005646-xhx9pzhj 1598 43 . . . cord-005646-xhx9pzhj 1599 1 None none NN cord-005646-xhx9pzhj 1599 2 of of IN cord-005646-xhx9pzhj 1599 3 the the DT cord-005646-xhx9pzhj 1599 4 varlables varlable NNS cord-005646-xhx9pzhj 1599 5 were be VBD cord-005646-xhx9pzhj 1599 6 changed change VBN cord-005646-xhx9pzhj 1599 7 by by IN cord-005646-xhx9pzhj 1599 8 saline saline NN cord-005646-xhx9pzhj 1599 9 . . . cord-005646-xhx9pzhj 1600 1 However however RB cord-005646-xhx9pzhj 1600 2 , , , cord-005646-xhx9pzhj 1600 3 significant significant JJ cord-005646-xhx9pzhj 1600 4 increases increase NNS cord-005646-xhx9pzhj 1600 5 in in IN cord-005646-xhx9pzhj 1600 6 ABP ABP NNP cord-005646-xhx9pzhj 1600 7 ( ( -LRB- cord-005646-xhx9pzhj 1600 8 p<0.0001 p<0.0001 NNP cord-005646-xhx9pzhj 1600 9 ) ) -RRB- cord-005646-xhx9pzhj 1600 10 , , , cord-005646-xhx9pzhj 1600 11 PAP pap NN cord-005646-xhx9pzhj 1600 12 ( ( -LRB- cord-005646-xhx9pzhj 1600 13 p<0.0001 p<0.0001 NNP cord-005646-xhx9pzhj 1600 14 ) ) -RRB- cord-005646-xhx9pzhj 1600 15 , , , cord-005646-xhx9pzhj 1600 16 CI CI NNP cord-005646-xhx9pzhj 1600 17 ( ( -LRB- cord-005646-xhx9pzhj 1600 18 p<0.001 p<0.001 JJ cord-005646-xhx9pzhj 1600 19 ) ) -RRB- cord-005646-xhx9pzhj 1600 20 and and CC cord-005646-xhx9pzhj 1600 21 SVR SVR NNP cord-005646-xhx9pzhj 1600 22 ( ( -LRB- cord-005646-xhx9pzhj 1600 23 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 1600 24 ) ) -RRB- cord-005646-xhx9pzhj 1600 25 were be VBD cord-005646-xhx9pzhj 1600 26 observed observe VBN cord-005646-xhx9pzhj 1600 27 after after IN cord-005646-xhx9pzhj 1600 28 administration administration NN cord-005646-xhx9pzhj 1600 29 of of IN cord-005646-xhx9pzhj 1600 30 adrenaline adrenaline NN cord-005646-xhx9pzhj 1600 31 , , , cord-005646-xhx9pzhj 1600 32 whiIe whiIe '' cord-005646-xhx9pzhj 1600 33 PVR PVR NNP cord-005646-xhx9pzhj 1600 34 and and CC cord-005646-xhx9pzhj 1600 35 ICA ICA NNP cord-005646-xhx9pzhj 1600 36 were be VBD cord-005646-xhx9pzhj 1600 37 not not RB cord-005646-xhx9pzhj 1600 38 modified modify VBN cord-005646-xhx9pzhj 1600 39 . . . cord-005646-xhx9pzhj 1601 1 Mean±SD Mean±SD NNP cord-005646-xhx9pzhj 1601 2 for for IN cord-005646-xhx9pzhj 1601 3 ABP ABP NNP cord-005646-xhx9pzhj 1601 4 / / SYM cord-005646-xhx9pzhj 1601 5 PAP pap NN cord-005646-xhx9pzhj 1601 6 ( ( -LRB- cord-005646-xhx9pzhj 1601 7 P p NN cord-005646-xhx9pzhj 1601 8 / / SYM cord-005646-xhx9pzhj 1601 9 A A NNP cord-005646-xhx9pzhj 1601 10 ) ) -RRB- cord-005646-xhx9pzhj 1601 11 , , , cord-005646-xhx9pzhj 1601 12 FVR FVR NNP cord-005646-xhx9pzhj 1601 13 / / SYM cord-005646-xhx9pzhj 1601 14 SVR SVR NNP cord-005646-xhx9pzhj 1601 15 ( ( -LRB- cord-005646-xhx9pzhj 1601 16 P p NN cord-005646-xhx9pzhj 1601 17 / / SYM cord-005646-xhx9pzhj 1601 18 S s NN cord-005646-xhx9pzhj 1601 19 ) ) -RRB- cord-005646-xhx9pzhj 1602 1 and and CC cord-005646-xhx9pzhj 1602 2 CI CI NNP cord-005646-xhx9pzhj 1602 3 ( ( -LRB- cord-005646-xhx9pzhj 1602 4 ml ml NN cord-005646-xhx9pzhj 1602 5 / / SYM cord-005646-xhx9pzhj 1602 6 mirdkg mirdkg NNP cord-005646-xhx9pzhj 1602 7 ) ) -RRB- cord-005646-xhx9pzhj 1602 8 were be VBD cord-005646-xhx9pzhj 1602 9 : : : cord-005646-xhx9pzhj 1602 10 Ratios ratio NNS cord-005646-xhx9pzhj 1602 11 of of IN cord-005646-xhx9pzhj 1602 12 PAP PAP NNP cord-005646-xhx9pzhj 1602 13 / / SYM cord-005646-xhx9pzhj 1602 14 ABP ABP NNP cord-005646-xhx9pzhj 1602 15 and and CC cord-005646-xhx9pzhj 1602 16 PVPJSVR PVPJSVR NNP cord-005646-xhx9pzhj 1602 17 significantly significantly RB cord-005646-xhx9pzhj 1602 18 increased increase VBD cord-005646-xhx9pzhj 1602 19 following follow VBG cord-005646-xhx9pzhj 1602 20 infusion infusion NN cord-005646-xhx9pzhj 1602 21 of of IN cord-005646-xhx9pzhj 1602 22 adrenaline adrenaline NN cord-005646-xhx9pzhj 1602 23 . . . cord-005646-xhx9pzhj 1603 1 These these DT cord-005646-xhx9pzhj 1603 2 data datum NNS cord-005646-xhx9pzhj 1603 3 suggest suggest VBP cord-005646-xhx9pzhj 1603 4 : : : cord-005646-xhx9pzhj 1603 5 1 1 LS cord-005646-xhx9pzhj 1603 6 ) ) -RRB- cord-005646-xhx9pzhj 1603 7 the the DT cord-005646-xhx9pzhj 1603 8 cerebral cerebral JJ cord-005646-xhx9pzhj 1603 9 perfusion perfusion NN cord-005646-xhx9pzhj 1603 10 is be VBZ cord-005646-xhx9pzhj 1603 11 preserved preserve VBN cord-005646-xhx9pzhj 1603 12 during during IN cord-005646-xhx9pzhj 1603 13 the the DT cord-005646-xhx9pzhj 1603 14 infusion infusion NN cord-005646-xhx9pzhj 1603 15 of of IN cord-005646-xhx9pzhj 1603 16 adrenaline adrenaline NN cord-005646-xhx9pzhj 1603 17 ; ; : cord-005646-xhx9pzhj 1603 18 2 2 LS cord-005646-xhx9pzhj 1603 19 ) ) -RRB- cord-005646-xhx9pzhj 1603 20 effect effect NN cord-005646-xhx9pzhj 1603 21 of of IN cord-005646-xhx9pzhj 1603 22 the the DT cord-005646-xhx9pzhj 1603 23 adrenaline adrenaline JJ cord-005646-xhx9pzhj 1603 24 infusion infusion NN cord-005646-xhx9pzhj 1603 25 on on IN cord-005646-xhx9pzhj 1603 26 the the DT cord-005646-xhx9pzhj 1603 27 systemic systemic JJ cord-005646-xhx9pzhj 1603 28 circulation circulation NN cord-005646-xhx9pzhj 1603 29 is be VBZ cord-005646-xhx9pzhj 1603 30 more more RBR cord-005646-xhx9pzhj 1603 31 pronounced pronounced JJ cord-005646-xhx9pzhj 1603 32 than than IN cord-005646-xhx9pzhj 1603 33 its -PRON- PRP$ cord-005646-xhx9pzhj 1603 34 effect effect NN cord-005646-xhx9pzhj 1603 35 on on IN cord-005646-xhx9pzhj 1603 36 the the DT cord-005646-xhx9pzhj 1603 37 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1603 38 circulation circulation NN cord-005646-xhx9pzhj 1603 39 in in IN cord-005646-xhx9pzhj 1603 40 newborn newborn JJ cord-005646-xhx9pzhj 1603 41 piglets piglet NNS cord-005646-xhx9pzhj 1603 42 with with IN cord-005646-xhx9pzhj 1603 43 surfactant surfactant NN cord-005646-xhx9pzhj 1603 44 deficiency deficiency NN cord-005646-xhx9pzhj 1603 45 . . . cord-005646-xhx9pzhj 1604 1 S S NNP cord-005646-xhx9pzhj 1604 2 Demirak Demirak NNP cord-005646-xhx9pzhj 1604 3 ~ ~ NFP cord-005646-xhx9pzhj 1604 4 a a LS cord-005646-xhx9pzhj 1604 5 , , , cord-005646-xhx9pzhj 1604 6 Ch Ch NNP cord-005646-xhx9pzhj 1604 7 Knothe Knothe NNP cord-005646-xhx9pzhj 1604 8 , , , cord-005646-xhx9pzhj 1604 9 KJ KJ NNP cord-005646-xhx9pzhj 1604 10 Hagel Hagel NNP cord-005646-xhx9pzhj 1604 11 , , , cord-005646-xhx9pzhj 1604 12 J J NNP cord-005646-xhx9pzhj 1604 13 Bauer Bauer NNP cord-005646-xhx9pzhj 1604 14 Department Department NNP cord-005646-xhx9pzhj 1604 15 of of IN cord-005646-xhx9pzhj 1604 16 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 1604 17 , , , cord-005646-xhx9pzhj 1604 18 Justus Justus NNP cord-005646-xhx9pzhj 1604 19 - - HYPH cord-005646-xhx9pzhj 1604 20 Liebig Liebig NNP cord-005646-xhx9pzhj 1604 21 - - HYPH cord-005646-xhx9pzhj 1604 22 University University NNP cord-005646-xhx9pzhj 1604 23 Giessen Giessen NNP cord-005646-xhx9pzhj 1604 24 , , , cord-005646-xhx9pzhj 1605 1 FRG FRG NNP cord-005646-xhx9pzhj 1605 2 Inhaled Inhaled NNP cord-005646-xhx9pzhj 1606 1 NO no UH cord-005646-xhx9pzhj 1606 2 is be VBZ cord-005646-xhx9pzhj 1606 3 a a DT cord-005646-xhx9pzhj 1606 4 short short JJ cord-005646-xhx9pzhj 1606 5 acting act VBG cord-005646-xhx9pzhj 1606 6 selective selective JJ cord-005646-xhx9pzhj 1606 7 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1606 8 vasodilator vasodilator NN cord-005646-xhx9pzhj 1606 9 . . . cord-005646-xhx9pzhj 1607 1 We -PRON- PRP cord-005646-xhx9pzhj 1607 2 studied study VBD cord-005646-xhx9pzhj 1607 3 the the DT cord-005646-xhx9pzhj 1607 4 effects effect NNS cord-005646-xhx9pzhj 1607 5 of of IN cord-005646-xhx9pzhj 1607 6 80 80 CD cord-005646-xhx9pzhj 1607 7 ppm ppm NN cord-005646-xhx9pzhj 1607 8 NO no NN cord-005646-xhx9pzhj 1607 9 and and CC cord-005646-xhx9pzhj 1607 10 100 100 CD cord-005646-xhx9pzhj 1607 11 % % NN cord-005646-xhx9pzhj 1607 12 oxygen oxygen NN cord-005646-xhx9pzhj 1607 13 during during IN cord-005646-xhx9pzhj 1607 14 heart heart NN cord-005646-xhx9pzhj 1607 15 catheterization catheterization NN cord-005646-xhx9pzhj 1607 16 in in IN cord-005646-xhx9pzhj 1607 17 16 16 CD cord-005646-xhx9pzhj 1607 18 children child NNS cord-005646-xhx9pzhj 1607 19 ( ( -LRB- cord-005646-xhx9pzhj 1607 20 age age NN cord-005646-xhx9pzhj 1607 21 1 1 CD cord-005646-xhx9pzhj 1607 22 -6 -6 CD cord-005646-xhx9pzhj 1607 23 years year NNS cord-005646-xhx9pzhj 1607 24 , , , cord-005646-xhx9pzhj 1607 25 median median NN cord-005646-xhx9pzhj 1607 26 9 9 CD cord-005646-xhx9pzhj 1607 27 years year NNS cord-005646-xhx9pzhj 1607 28 ) ) -RRB- cord-005646-xhx9pzhj 1607 29 with with IN cord-005646-xhx9pzhj 1607 30 heart heart NN cord-005646-xhx9pzhj 1607 31 defects defect NNS cord-005646-xhx9pzhj 1607 32 and and CC cord-005646-xhx9pzhj 1607 33 elevated elevated JJ cord-005646-xhx9pzhj 1607 34 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1607 35 vascular vascular JJ cord-005646-xhx9pzhj 1607 36 resistance resistance NN cord-005646-xhx9pzhj 1607 37 index index NN cord-005646-xhx9pzhj 1607 38 ( ( -LRB- cord-005646-xhx9pzhj 1607 39 PVRi PVRi NNP cord-005646-xhx9pzhj 1607 40 ) ) -RRB- cord-005646-xhx9pzhj 1607 41 in in IN cord-005646-xhx9pzhj 1607 42 order order NN cord-005646-xhx9pzhj 1607 43 to to IN cord-005646-xhx9pzhj 1607 44 asses ass NNS cord-005646-xhx9pzhj 1607 45 the the DT cord-005646-xhx9pzhj 1607 46 value value NN cord-005646-xhx9pzhj 1607 47 of of IN cord-005646-xhx9pzhj 1607 48 NO no NN cord-005646-xhx9pzhj 1607 49 as as IN cord-005646-xhx9pzhj 1607 50 a a DT cord-005646-xhx9pzhj 1607 51 tool tool NN cord-005646-xhx9pzhj 1607 52 of of IN cord-005646-xhx9pzhj 1607 53 decision decision NN cord-005646-xhx9pzhj 1607 54 making make VBG cord-005646-xhx9pzhj 1607 55 for for IN cord-005646-xhx9pzhj 1607 56 corrective corrective JJ cord-005646-xhx9pzhj 1607 57 cardiac cardiac JJ cord-005646-xhx9pzhj 1607 58 surgery surgery NN cord-005646-xhx9pzhj 1607 59 . . . cord-005646-xhx9pzhj 1608 1 Patients patient NNS cord-005646-xhx9pzhj 1608 2 were be VBD cord-005646-xhx9pzhj 1608 3 eligible eligible JJ cord-005646-xhx9pzhj 1608 4 for for IN cord-005646-xhx9pzhj 1608 5 testing testing NN cord-005646-xhx9pzhj 1608 6 when when WRB cord-005646-xhx9pzhj 1608 7 they -PRON- PRP cord-005646-xhx9pzhj 1608 8 were be VBD cord-005646-xhx9pzhj 1608 9 more more JJR cord-005646-xhx9pzhj 1608 10 than than IN cord-005646-xhx9pzhj 1608 11 one one CD cord-005646-xhx9pzhj 1608 12 year year NN cord-005646-xhx9pzhj 1608 13 old old JJ cord-005646-xhx9pzhj 1608 14 and and CC cord-005646-xhx9pzhj 1608 15 had have VBD cord-005646-xhx9pzhj 1608 16 a a DT cord-005646-xhx9pzhj 1608 17 pathologically pathologically RB cord-005646-xhx9pzhj 1608 18 elevated elevated JJ cord-005646-xhx9pzhj 1608 19 PVRi PVRi NNS cord-005646-xhx9pzhj 1608 20 in in IN cord-005646-xhx9pzhj 1608 21 a a DT cord-005646-xhx9pzhj 1608 22 previous previous JJ cord-005646-xhx9pzhj 1608 23 heart heart NN cord-005646-xhx9pzhj 1608 24 catheterization catheterization NN cord-005646-xhx9pzhj 1608 25 . . . cord-005646-xhx9pzhj 1609 1 Intubation intubation NN cord-005646-xhx9pzhj 1609 2 , , , cord-005646-xhx9pzhj 1609 3 ' ' '' cord-005646-xhx9pzhj 1609 4 anesthesia anesthesia NN cord-005646-xhx9pzhj 1609 5 and and CC cord-005646-xhx9pzhj 1609 6 muscle muscle NN cord-005646-xhx9pzhj 1609 7 paralysis paralysis NN cord-005646-xhx9pzhj 1609 8 were be VBD cord-005646-xhx9pzhj 1609 9 performed perform VBN cord-005646-xhx9pzhj 1609 10 in in IN cord-005646-xhx9pzhj 1609 11 all all DT cord-005646-xhx9pzhj 1609 12 patients patient NNS cord-005646-xhx9pzhj 1609 13 during during IN cord-005646-xhx9pzhj 1609 14 testing testing NN cord-005646-xhx9pzhj 1609 15 of of IN cord-005646-xhx9pzhj 1609 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1609 17 reagibility reagibility NN cord-005646-xhx9pzhj 1609 18 . . . cord-005646-xhx9pzhj 1610 1 Calculations calculation NNS cord-005646-xhx9pzhj 1610 2 of of IN cord-005646-xhx9pzhj 1610 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1610 4 vascular vascular JJ cord-005646-xhx9pzhj 1610 5 resistance resistance NN cord-005646-xhx9pzhj 1610 6 and and CC cord-005646-xhx9pzhj 1610 7 flow flow NN cord-005646-xhx9pzhj 1610 8 were be VBD cord-005646-xhx9pzhj 1610 9 based base VBN cord-005646-xhx9pzhj 1610 10 on on IN cord-005646-xhx9pzhj 1610 11 the the DT cord-005646-xhx9pzhj 1610 12 Fick Fick NNP cord-005646-xhx9pzhj 1610 13 method method NN cord-005646-xhx9pzhj 1610 14 . . . cord-005646-xhx9pzhj 1611 1 Response response NN cord-005646-xhx9pzhj 1611 2 to to IN cord-005646-xhx9pzhj 1611 3 NO no DT cord-005646-xhx9pzhj 1611 4 was be VBD cord-005646-xhx9pzhj 1611 5 assumed assume VBN cord-005646-xhx9pzhj 1611 6 when when WRB cord-005646-xhx9pzhj 1611 7 PVRi PVRi NNS cord-005646-xhx9pzhj 1611 8 declined decline VBD cord-005646-xhx9pzhj 1611 9 more more JJR cord-005646-xhx9pzhj 1611 10 than than IN cord-005646-xhx9pzhj 1611 11 30 30 CD cord-005646-xhx9pzhj 1611 12 % % NN cord-005646-xhx9pzhj 1611 13 , , , cord-005646-xhx9pzhj 1611 14 9 9 CD cord-005646-xhx9pzhj 1611 15 of of IN cord-005646-xhx9pzhj 1611 16 the the DT cord-005646-xhx9pzhj 1611 17 16 16 CD cord-005646-xhx9pzhj 1611 18 patients patient NNS cord-005646-xhx9pzhj 1611 19 were be VBD cord-005646-xhx9pzhj 1611 20 responders responder NNS cord-005646-xhx9pzhj 1611 21 to to IN cord-005646-xhx9pzhj 1611 22 NO no NN cord-005646-xhx9pzhj 1611 23 . . . cord-005646-xhx9pzhj 1612 1 Effects effect NNS cord-005646-xhx9pzhj 1612 2 of of IN cord-005646-xhx9pzhj 1612 3 NO no NN cord-005646-xhx9pzhj 1612 4 and and CC cord-005646-xhx9pzhj 1612 5 oxygen oxygen NN cord-005646-xhx9pzhj 1612 6 on on IN cord-005646-xhx9pzhj 1612 7 PVRi PVRi NNS cord-005646-xhx9pzhj 1612 8 , , , cord-005646-xhx9pzhj 1612 9 mean mean VBP cord-005646-xhx9pzhj 1612 10 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1612 11 arterial arterial JJ cord-005646-xhx9pzhj 1612 12 pressure pressure NN cord-005646-xhx9pzhj 1612 13 ( ( -LRB- cord-005646-xhx9pzhj 1612 14 mPAP mpap NN cord-005646-xhx9pzhj 1612 15 ) ) -RRB- cord-005646-xhx9pzhj 1612 16 and and CC cord-005646-xhx9pzhj 1612 17 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1612 18 vascular vascular JJ cord-005646-xhx9pzhj 1612 19 flow flow NN cord-005646-xhx9pzhj 1612 20 ( ( -LRB- cord-005646-xhx9pzhj 1612 21 Qp Qp NNP cord-005646-xhx9pzhj 1612 22 ) ) -RRB- cord-005646-xhx9pzhj 1612 23 in in IN cord-005646-xhx9pzhj 1612 24 all all DT cord-005646-xhx9pzhj 1612 25 responders responder NNS cord-005646-xhx9pzhj 1612 26 are be VBP cord-005646-xhx9pzhj 1612 27 described describe VBN cord-005646-xhx9pzhj 1612 28 in in IN cord-005646-xhx9pzhj 1612 29 the the DT cord-005646-xhx9pzhj 1612 30 table table NN cord-005646-xhx9pzhj 1612 31 below below RB cord-005646-xhx9pzhj 1612 32 . . . cord-005646-xhx9pzhj 1613 1 Cardiac cardiac JJ cord-005646-xhx9pzhj 1613 2 surgery surgery NN cord-005646-xhx9pzhj 1613 3 was be VBD cord-005646-xhx9pzhj 1613 4 offered offer VBN cord-005646-xhx9pzhj 1613 5 to to IN cord-005646-xhx9pzhj 1613 6 all all DT cord-005646-xhx9pzhj 1613 7 responders responder NNS cord-005646-xhx9pzhj 1613 8 , , , cord-005646-xhx9pzhj 1613 9 and and CC cord-005646-xhx9pzhj 1613 10 5 5 CD cord-005646-xhx9pzhj 1613 11 of of IN cord-005646-xhx9pzhj 1613 12 them -PRON- PRP cord-005646-xhx9pzhj 1613 13 were be VBD cord-005646-xhx9pzhj 1613 14 successfully successfully RB cord-005646-xhx9pzhj 1613 15 operated operate VBN cord-005646-xhx9pzhj 1613 16 . . . cord-005646-xhx9pzhj 1614 1 Surgery surgery NN cord-005646-xhx9pzhj 1614 2 is be VBZ cord-005646-xhx9pzhj 1614 3 planned plan VBN cord-005646-xhx9pzhj 1614 4 in in IN cord-005646-xhx9pzhj 1614 5 another another DT cord-005646-xhx9pzhj 1614 6 3 3 CD cord-005646-xhx9pzhj 1614 7 patients patient NNS cord-005646-xhx9pzhj 1614 8 and and CC cord-005646-xhx9pzhj 1614 9 parental parental JJ cord-005646-xhx9pzhj 1614 10 consent consent NN cord-005646-xhx9pzhj 1614 11 for for IN cord-005646-xhx9pzhj 1614 12 surgery surgery NN cord-005646-xhx9pzhj 1614 13 was be VBD cord-005646-xhx9pzhj 1614 14 not not RB cord-005646-xhx9pzhj 1614 15 given give VBN cord-005646-xhx9pzhj 1614 16 in in IN cord-005646-xhx9pzhj 1614 17 one one CD cord-005646-xhx9pzhj 1614 18 patient patient NN cord-005646-xhx9pzhj 1614 19 . . . cord-005646-xhx9pzhj 1615 1 In in IN cord-005646-xhx9pzhj 1615 2 Ebstein Ebstein NNP cord-005646-xhx9pzhj 1615 3 disease disease NN cord-005646-xhx9pzhj 1615 4 , , , cord-005646-xhx9pzhj 1615 5 during during IN cord-005646-xhx9pzhj 1615 6 the the DT cord-005646-xhx9pzhj 1615 7 first first JJ cord-005646-xhx9pzhj 1615 8 days day NNS cord-005646-xhx9pzhj 1615 9 of of IN cord-005646-xhx9pzhj 1615 10 life life NN cord-005646-xhx9pzhj 1615 11 , , , cord-005646-xhx9pzhj 1615 12 the the DT cord-005646-xhx9pzhj 1615 13 ability ability NN cord-005646-xhx9pzhj 1615 14 of of IN cord-005646-xhx9pzhj 1615 15 right right JJ cord-005646-xhx9pzhj 1615 16 ventricle ventricle NN cord-005646-xhx9pzhj 1615 17 to to TO cord-005646-xhx9pzhj 1615 18 propel propel VB cord-005646-xhx9pzhj 1615 19 blood blood NN cord-005646-xhx9pzhj 1615 20 to to IN cord-005646-xhx9pzhj 1615 21 the the DT cord-005646-xhx9pzhj 1615 22 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1615 23 artery artery NN cord-005646-xhx9pzhj 1615 24 is be VBZ cord-005646-xhx9pzhj 1615 25 impaired impair VBN cord-005646-xhx9pzhj 1615 26 due due IN cord-005646-xhx9pzhj 1615 27 to to IN cord-005646-xhx9pzhj 1615 28 high high JJ cord-005646-xhx9pzhj 1615 29 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1615 30 vascular vascular JJ cord-005646-xhx9pzhj 1615 31 resistances resistance NNS cord-005646-xhx9pzhj 1615 32 . . . cord-005646-xhx9pzhj 1616 1 The the DT cord-005646-xhx9pzhj 1616 2 flow flow NN cord-005646-xhx9pzhj 1616 3 is be VBZ cord-005646-xhx9pzhj 1616 4 mainly mainly RB cord-005646-xhx9pzhj 1616 5 directed direct VBN cord-005646-xhx9pzhj 1616 6 to to IN cord-005646-xhx9pzhj 1616 7 left leave VBN cord-005646-xhx9pzhj 1616 8 atrium atrium NN cord-005646-xhx9pzhj 1616 9 through through IN cord-005646-xhx9pzhj 1616 10 tricuspid tricuspid JJ cord-005646-xhx9pzhj 1616 11 insufficiency insufficiency NN cord-005646-xhx9pzhj 1616 12 , , , cord-005646-xhx9pzhj 1616 13 right right JJ cord-005646-xhx9pzhj 1616 14 atrium atrium NN cord-005646-xhx9pzhj 1616 15 and and CC cord-005646-xhx9pzhj 1616 16 foramen foramen NNP cord-005646-xhx9pzhj 1616 17 ovale ovale NN cord-005646-xhx9pzhj 1616 18 . . . cord-005646-xhx9pzhj 1617 1 To to TO cord-005646-xhx9pzhj 1617 2 decrease decrease VB cord-005646-xhx9pzhj 1617 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1617 4 resistances resistance NNS cord-005646-xhx9pzhj 1617 5 and and CC cord-005646-xhx9pzhj 1617 6 increase increase VB cord-005646-xhx9pzhj 1617 7 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1617 8 blood blood NN cord-005646-xhx9pzhj 1617 9 flow flow NN cord-005646-xhx9pzhj 1617 10 , , , cord-005646-xhx9pzhj 1617 11 high high JJ cord-005646-xhx9pzhj 1617 12 frequency frequency NN cord-005646-xhx9pzhj 1617 13 oscillations oscillation NNS cord-005646-xhx9pzhj 1617 14 , , , cord-005646-xhx9pzhj 1617 15 mechanical mechanical JJ cord-005646-xhx9pzhj 1617 16 ventilation ventilation NN cord-005646-xhx9pzhj 1617 17 , , , cord-005646-xhx9pzhj 1617 18 nitric nitric NN cord-005646-xhx9pzhj 1617 19 oxide oxide NN cord-005646-xhx9pzhj 1617 20 and and CC cord-005646-xhx9pzhj 1617 21 prostaglandin prostaglandin NN cord-005646-xhx9pzhj 1617 22 are be VBP cord-005646-xhx9pzhj 1617 23 required require VBN cord-005646-xhx9pzhj 1617 24 . . . cord-005646-xhx9pzhj 1618 1 After after IN cord-005646-xhx9pzhj 1618 2 few few JJ cord-005646-xhx9pzhj 1618 3 days day NNS cord-005646-xhx9pzhj 1618 4 , , , cord-005646-xhx9pzhj 1618 5 a a DT cord-005646-xhx9pzhj 1618 6 forward forward JJ cord-005646-xhx9pzhj 1618 7 circulation circulation NN cord-005646-xhx9pzhj 1618 8 is be VBZ cord-005646-xhx9pzhj 1618 9 normally normally RB cord-005646-xhx9pzhj 1618 10 established establish VBN cord-005646-xhx9pzhj 1618 11 . . . cord-005646-xhx9pzhj 1619 1 We -PRON- PRP cord-005646-xhx9pzhj 1619 2 cared care VBD cord-005646-xhx9pzhj 1619 3 two two CD cord-005646-xhx9pzhj 1619 4 newborns newborn NNS cord-005646-xhx9pzhj 1619 5 with with IN cord-005646-xhx9pzhj 1619 6 Ebstein Ebstein NNP cord-005646-xhx9pzhj 1619 7 disease disease NN cord-005646-xhx9pzhj 1619 8 where where WRB cord-005646-xhx9pzhj 1619 9 this this DT cord-005646-xhx9pzhj 1619 10 approach approach NN cord-005646-xhx9pzhj 1619 11 was be VBD cord-005646-xhx9pzhj 1619 12 hindered hinder VBN cord-005646-xhx9pzhj 1619 13 by by IN cord-005646-xhx9pzhj 1619 14 a a DT cord-005646-xhx9pzhj 1619 15 large large JJ cord-005646-xhx9pzhj 1619 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1619 17 valve valve NN cord-005646-xhx9pzhj 1619 18 insufficiency insufficiency NN cord-005646-xhx9pzhj 1619 19 . . . cord-005646-xhx9pzhj 1620 1 Both both DT cord-005646-xhx9pzhj 1620 2 of of IN cord-005646-xhx9pzhj 1620 3 them -PRON- PRP cord-005646-xhx9pzhj 1620 4 were be VBD cord-005646-xhx9pzhj 1620 5 diagnosed diagnose VBN cord-005646-xhx9pzhj 1620 6 in in IN cord-005646-xhx9pzhj 1620 7 utero utero NN cord-005646-xhx9pzhj 1620 8 , , , cord-005646-xhx9pzhj 1620 9 showing show VBG cord-005646-xhx9pzhj 1620 10 a a DT cord-005646-xhx9pzhj 1620 11 large large JJ cord-005646-xhx9pzhj 1620 12 tricuspid tricuspid JJ cord-005646-xhx9pzhj 1620 13 insufficiency insufficiency NN cord-005646-xhx9pzhj 1620 14 with with IN cord-005646-xhx9pzhj 1620 15 a a DT cord-005646-xhx9pzhj 1620 16 non non JJ cord-005646-xhx9pzhj 1620 17 opened open VBN cord-005646-xhx9pzhj 1620 18 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1620 19 valve valve NN cord-005646-xhx9pzhj 1620 20 and and CC cord-005646-xhx9pzhj 1620 21 a a DT cord-005646-xhx9pzhj 1620 22 ductal ductal JJ cord-005646-xhx9pzhj 1620 23 left left NN cord-005646-xhx9pzhj 1620 24 to to IN cord-005646-xhx9pzhj 1620 25 right right JJ cord-005646-xhx9pzhj 1620 26 shunt shunt NN cord-005646-xhx9pzhj 1620 27 . . . cord-005646-xhx9pzhj 1621 1 One one CD cord-005646-xhx9pzhj 1621 2 fetus fetus NN cord-005646-xhx9pzhj 1621 3 was be VBD cord-005646-xhx9pzhj 1621 4 hydropic hydropic NNP cord-005646-xhx9pzhj 1621 5 . . . cord-005646-xhx9pzhj 1622 1 At at IN cord-005646-xhx9pzhj 1622 2 birth birth NN cord-005646-xhx9pzhj 1622 3 , , , cord-005646-xhx9pzhj 1622 4 blood blood NN cord-005646-xhx9pzhj 1622 5 stream stream NN cord-005646-xhx9pzhj 1622 6 from from IN cord-005646-xhx9pzhj 1622 7 the the DT cord-005646-xhx9pzhj 1622 8 ductus ductus NN cord-005646-xhx9pzhj 1622 9 arteriosus arteriosus NN cord-005646-xhx9pzhj 1622 10 was be VBD cord-005646-xhx9pzhj 1622 11 directed direct VBN cord-005646-xhx9pzhj 1622 12 to to IN cord-005646-xhx9pzhj 1622 13 the the DT cord-005646-xhx9pzhj 1622 14 right right JJ cord-005646-xhx9pzhj 1622 15 ventricle ventricle NN cord-005646-xhx9pzhj 1622 16 through through IN cord-005646-xhx9pzhj 1622 17 the the DT cord-005646-xhx9pzhj 1622 18 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1622 19 valve valve NN cord-005646-xhx9pzhj 1622 20 insufficiency insufficiency NN cord-005646-xhx9pzhj 1622 21 then then RB cord-005646-xhx9pzhj 1622 22 to to IN cord-005646-xhx9pzhj 1622 23 right right JJ cord-005646-xhx9pzhj 1622 24 atrium atrium NN cord-005646-xhx9pzhj 1622 25 , , , cord-005646-xhx9pzhj 1622 26 left leave VBN cord-005646-xhx9pzhj 1622 27 atrium atrium NN cord-005646-xhx9pzhj 1622 28 and and CC cord-005646-xhx9pzhj 1622 29 ventricle ventricle NN cord-005646-xhx9pzhj 1622 30 , , , cord-005646-xhx9pzhj 1622 31 aorta aorta NN cord-005646-xhx9pzhj 1622 32 and and CC cord-005646-xhx9pzhj 1622 33 ductus ductus NN cord-005646-xhx9pzhj 1622 34 arteriosus arteriosus NN cord-005646-xhx9pzhj 1622 35 . . . cord-005646-xhx9pzhj 1623 1 A a DT cord-005646-xhx9pzhj 1623 2 low low JJ cord-005646-xhx9pzhj 1623 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1623 4 blood blood NN cord-005646-xhx9pzhj 1623 5 flow flow NN cord-005646-xhx9pzhj 1623 6 was be VBD cord-005646-xhx9pzhj 1623 7 demonstrated demonstrate VBN cord-005646-xhx9pzhj 1623 8 by by IN cord-005646-xhx9pzhj 1623 9 low low JJ cord-005646-xhx9pzhj 1623 10 mean mean JJ cord-005646-xhx9pzhj 1623 11 velocities velocity NNS cord-005646-xhx9pzhj 1623 12 ( ( -LRB- cord-005646-xhx9pzhj 1623 13 10cm 10cm NNP cord-005646-xhx9pzhj 1623 14 / / SYM cord-005646-xhx9pzhj 1623 15 sec sec NNP cord-005646-xhx9pzhj 1623 16 ) ) -RRB- cord-005646-xhx9pzhj 1623 17 . . . cord-005646-xhx9pzhj 1624 1 A a DT cord-005646-xhx9pzhj 1624 2 high high JJ cord-005646-xhx9pzhj 1624 3 reverse reverse JJ cord-005646-xhx9pzhj 1624 4 flow flow NN cord-005646-xhx9pzhj 1624 5 was be VBD cord-005646-xhx9pzhj 1624 6 seen see VBN cord-005646-xhx9pzhj 1624 7 in in IN cord-005646-xhx9pzhj 1624 8 descending descend VBG cord-005646-xhx9pzhj 1624 9 aorta aorta NN cord-005646-xhx9pzhj 1624 10 with with IN cord-005646-xhx9pzhj 1624 11 a a DT cord-005646-xhx9pzhj 1624 12 negative negative JJ cord-005646-xhx9pzhj 1624 13 flow flow NN cord-005646-xhx9pzhj 1624 14 in in IN cord-005646-xhx9pzhj 1624 15 the the DT cord-005646-xhx9pzhj 1624 16 renal renal JJ cord-005646-xhx9pzhj 1624 17 artery artery NN cord-005646-xhx9pzhj 1624 18 . . . cord-005646-xhx9pzhj 1625 1 Both both DT cord-005646-xhx9pzhj 1625 2 of of IN cord-005646-xhx9pzhj 1625 3 these these DT cord-005646-xhx9pzhj 1625 4 newborns newborn NNS cord-005646-xhx9pzhj 1625 5 were be VBD cord-005646-xhx9pzhj 1625 6 oliguric oliguric JJ cord-005646-xhx9pzhj 1625 7 because because IN cord-005646-xhx9pzhj 1625 8 of of IN cord-005646-xhx9pzhj 1625 9 ductus ductus NN cord-005646-xhx9pzhj 1625 10 arteriosus arteriosus NN cord-005646-xhx9pzhj 1625 11 steal steal NN cord-005646-xhx9pzhj 1625 12 . . . cord-005646-xhx9pzhj 1626 1 Pulmonary pulmonary JJ cord-005646-xhx9pzhj 1626 2 blood blood NN cord-005646-xhx9pzhj 1626 3 flow flow NN cord-005646-xhx9pzhj 1626 4 Doppler doppler NN cord-005646-xhx9pzhj 1626 5 evaluation evaluation NN cord-005646-xhx9pzhj 1626 6 allowed allow VBD cord-005646-xhx9pzhj 1626 7 different different JJ cord-005646-xhx9pzhj 1626 8 strategies strategy NNS cord-005646-xhx9pzhj 1626 9 of of IN cord-005646-xhx9pzhj 1626 10 ventilation ventilation NN cord-005646-xhx9pzhj 1626 11 , , , cord-005646-xhx9pzhj 1626 12 switching switch VBG cord-005646-xhx9pzhj 1626 13 between between IN cord-005646-xhx9pzhj 1626 14 HFO HFO NNP cord-005646-xhx9pzhj 1626 15 and and CC cord-005646-xhx9pzhj 1626 16 conventional conventional JJ cord-005646-xhx9pzhj 1626 17 ventilation ventilation NN cord-005646-xhx9pzhj 1626 18 , , , cord-005646-xhx9pzhj 1626 19 modulation modulation NN cord-005646-xhx9pzhj 1626 20 of of IN cord-005646-xhx9pzhj 1626 21 PGE1 PGE1 NNP cord-005646-xhx9pzhj 1626 22 doses dose NNS cord-005646-xhx9pzhj 1626 23 , , , cord-005646-xhx9pzhj 1626 24 inhaled inhale VBN cord-005646-xhx9pzhj 1626 25 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1626 26 vasodilators vasodilator NNS cord-005646-xhx9pzhj 1626 27 ( ( -LRB- cord-005646-xhx9pzhj 1626 28 nitric nitric JJ cord-005646-xhx9pzhj 1626 29 oxide oxide NN cord-005646-xhx9pzhj 1626 30 ) ) -RRB- cord-005646-xhx9pzhj 1626 31 and and CC cord-005646-xhx9pzhj 1626 32 surfactant surfactant NN cord-005646-xhx9pzhj 1626 33 . . . cord-005646-xhx9pzhj 1627 1 The the DT cord-005646-xhx9pzhj 1627 2 hydropic hydropic NN cord-005646-xhx9pzhj 1627 3 baby baby NN cord-005646-xhx9pzhj 1627 4 died die VBD cord-005646-xhx9pzhj 1627 5 , , , cord-005646-xhx9pzhj 1627 6 the the DT cord-005646-xhx9pzhj 1627 7 other other JJ cord-005646-xhx9pzhj 1627 8 survived survive VBD cord-005646-xhx9pzhj 1627 9 after after IN cord-005646-xhx9pzhj 1627 10 3 3 CD cord-005646-xhx9pzhj 1627 11 weeks week NNS cord-005646-xhx9pzhj 1627 12 of of IN cord-005646-xhx9pzhj 1627 13 intensive intensive JJ cord-005646-xhx9pzhj 1627 14 care care NN cord-005646-xhx9pzhj 1627 15 complicated complicate VBN cord-005646-xhx9pzhj 1627 16 by by IN cord-005646-xhx9pzhj 1627 17 supraventricular supraventricular JJ cord-005646-xhx9pzhj 1627 18 arythmia arythmia NN cord-005646-xhx9pzhj 1627 19 ( ( -LRB- cord-005646-xhx9pzhj 1627 20 WPW WPW NNP cord-005646-xhx9pzhj 1627 21 ) ) -RRB- cord-005646-xhx9pzhj 1627 22 . . . cord-005646-xhx9pzhj 1628 1 In in IN cord-005646-xhx9pzhj 1628 2 conclusion conclusion NN cord-005646-xhx9pzhj 1628 3 , , , cord-005646-xhx9pzhj 1628 4 during during IN cord-005646-xhx9pzhj 1628 5 neonatal neonatal JJ cord-005646-xhx9pzhj 1628 6 period period NN cord-005646-xhx9pzhj 1628 7 , , , cord-005646-xhx9pzhj 1628 8 in in IN cord-005646-xhx9pzhj 1628 9 Ebstein Ebstein NNP cord-005646-xhx9pzhj 1628 10 disease disease NN cord-005646-xhx9pzhj 1628 11 , , , cord-005646-xhx9pzhj 1628 12 a a DT cord-005646-xhx9pzhj 1628 13 large large JJ cord-005646-xhx9pzhj 1628 14 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1628 15 insufficiency insufficiency NN cord-005646-xhx9pzhj 1628 16 leads lead VBZ cord-005646-xhx9pzhj 1628 17 to to IN cord-005646-xhx9pzhj 1628 18 a a DT cord-005646-xhx9pzhj 1628 19 vicious vicious JJ cord-005646-xhx9pzhj 1628 20 circle circle NN cord-005646-xhx9pzhj 1628 21 where where WRB cord-005646-xhx9pzhj 1628 22 lungs lung NNS cord-005646-xhx9pzhj 1628 23 are be VBP cord-005646-xhx9pzhj 1628 24 excluded exclude VBN cord-005646-xhx9pzhj 1628 25 , , , cord-005646-xhx9pzhj 1628 26 inducing induce VBG cord-005646-xhx9pzhj 1628 27 severe severe JJ cord-005646-xhx9pzhj 1628 28 asphyxia asphyxia NN cord-005646-xhx9pzhj 1628 29 and and CC cord-005646-xhx9pzhj 1628 30 high high JJ cord-005646-xhx9pzhj 1628 31 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1628 32 resistances resistance NNS cord-005646-xhx9pzhj 1628 33 . . . cord-005646-xhx9pzhj 1629 1 The the DT cord-005646-xhx9pzhj 1629 2 blood blood NN cord-005646-xhx9pzhj 1629 3 is be VBZ cord-005646-xhx9pzhj 1629 4 backward backward RB cord-005646-xhx9pzhj 1629 5 propeled propeled JJ cord-005646-xhx9pzhj 1629 6 from from IN cord-005646-xhx9pzhj 1629 7 the the DT cord-005646-xhx9pzhj 1629 8 aorta aorta NN cord-005646-xhx9pzhj 1629 9 through through IN cord-005646-xhx9pzhj 1629 10 the the DT cord-005646-xhx9pzhj 1629 11 ductus ductus NN cord-005646-xhx9pzhj 1629 12 arteriosus arteriosus NN cord-005646-xhx9pzhj 1629 13 to to IN cord-005646-xhx9pzhj 1629 14 the the DT cord-005646-xhx9pzhj 1629 15 right right JJ cord-005646-xhx9pzhj 1629 16 ventricle ventricle NN cord-005646-xhx9pzhj 1629 17 and and CC cord-005646-xhx9pzhj 1629 18 atria atria NN cord-005646-xhx9pzhj 1629 19 , , , cord-005646-xhx9pzhj 1629 20 then then RB cord-005646-xhx9pzhj 1629 21 left leave VBD cord-005646-xhx9pzhj 1629 22 cavities cavity NNS cord-005646-xhx9pzhj 1629 23 to to IN cord-005646-xhx9pzhj 1629 24 aorta aorta NN cord-005646-xhx9pzhj 1629 25 . . . cord-005646-xhx9pzhj 1630 1 AREC AREC NNP cord-005646-xhx9pzhj 1630 2 must must MD cord-005646-xhx9pzhj 1630 3 be be VB cord-005646-xhx9pzhj 1630 4 considered consider VBN cord-005646-xhx9pzhj 1630 5 when when WRB cord-005646-xhx9pzhj 1630 6 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1630 7 blood blood NN cord-005646-xhx9pzhj 1630 8 flow flow NN cord-005646-xhx9pzhj 1630 9 does do VBZ cord-005646-xhx9pzhj 1630 10 not not RB cord-005646-xhx9pzhj 1630 11 increase increase VB cord-005646-xhx9pzhj 1630 12 despite despite IN cord-005646-xhx9pzhj 1630 13 optimal optimal JJ cord-005646-xhx9pzhj 1630 14 therapy therapy NN cord-005646-xhx9pzhj 1630 15 . . . cord-005646-xhx9pzhj 1631 1 Guti~ Guti~ NNP cord-005646-xhx9pzhj 1632 1 rrez rrez NNP cord-005646-xhx9pzhj 1632 2 - - HYPH cord-005646-xhx9pzhj 1632 3 Larraya Larraya NNP cord-005646-xhx9pzhj 1632 4 F F NNP cord-005646-xhx9pzhj 1632 5 * * NFP cord-005646-xhx9pzhj 1632 6 , , , cord-005646-xhx9pzhj 1632 7 Mandoza Mandoza NNP cord-005646-xhx9pzhj 1632 8 A A NNP cord-005646-xhx9pzhj 1632 9 * * NFP cord-005646-xhx9pzhj 1632 10 , , , cord-005646-xhx9pzhj 1632 11 Velasco Velasco NNP cord-005646-xhx9pzhj 1632 12 JM JM NNP cord-005646-xhx9pzhj 1632 13 * * NFP cord-005646-xhx9pzhj 1632 14 , , , cord-005646-xhx9pzhj 1632 15 ZavaneUa ZavaneUa NNP cord-005646-xhx9pzhj 1632 16 ( ( -LRB- cord-005646-xhx9pzhj 1632 17 3 3 CD cord-005646-xhx9pzhj 1633 1 * * NFP cord-005646-xhx9pzhj 1633 2 * * NFP cord-005646-xhx9pzhj 1633 3 , , , cord-005646-xhx9pzhj 1633 4 Gatindo Gatindo NNP cord-005646-xhx9pzhj 1633 5 A A NNP cord-005646-xhx9pzhj 1633 6 ~ ~ NFP cord-005646-xhx9pzhj 1634 1 , , , cord-005646-xhx9pzhj 1634 2 S&nchez S&nchez NNP cord-005646-xhx9pzhj 1634 3 - - HYPH cord-005646-xhx9pzhj 1634 4 Andrede Andrede NNP cord-005646-xhx9pzhj 1634 5 R r NN cord-005646-xhx9pzhj 1634 6 , , , cord-005646-xhx9pzhj 1634 7 S&nchez S&nchez NNP cord-005646-xhx9pzhj 1634 8 Jl Jl NNP cord-005646-xhx9pzhj 1635 1 * * NFP cord-005646-xhx9pzhj 1635 2 * * NFP cord-005646-xhx9pzhj 1635 3 * * NFP cord-005646-xhx9pzhj 1635 4 , , , cord-005646-xhx9pzhj 1635 5 MellOn MellOn NNP cord-005646-xhx9pzhj 1635 6 A a DT cord-005646-xhx9pzhj 1635 7 * * NFP cord-005646-xhx9pzhj 1635 8 * * NFP cord-005646-xhx9pzhj 1635 9 * * NFP cord-005646-xhx9pzhj 1635 10 , , , cord-005646-xhx9pzhj 1635 11 Mar Mar NNP cord-005646-xhx9pzhj 1635 12 F F NNP cord-005646-xhx9pzhj 1635 13 * * NFP cord-005646-xhx9pzhj 1635 14 * * NFP cord-005646-xhx9pzhj 1635 15 * * NFP cord-005646-xhx9pzhj 1635 16 . . . cord-005646-xhx9pzhj 1636 1 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1636 2 Cardiology Cardiology NNP cord-005646-xhx9pzhj 1637 1 * * NFP cord-005646-xhx9pzhj 1637 2 , , , cord-005646-xhx9pzhj 1637 3 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1637 4 Cardiac Cardiac NNP cord-005646-xhx9pzhj 1637 5 Surgery surgery NN cord-005646-xhx9pzhj 1638 1 * * NFP cord-005646-xhx9pzhj 1638 2 * * NFP cord-005646-xhx9pzhj 1638 3 , , , cord-005646-xhx9pzhj 1638 4 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1638 5 Intensive Intensive NNP cord-005646-xhx9pzhj 1638 6 Care Care NNP cord-005646-xhx9pzhj 1638 7 Unit Unit NNP cord-005646-xhx9pzhj 1639 1 * * NFP cord-005646-xhx9pzhj 1639 2 * * NFP cord-005646-xhx9pzhj 1639 3 * * NFP cord-005646-xhx9pzhj 1639 4 . . . cord-005646-xhx9pzhj 1640 1 Hospital hospital NN cord-005646-xhx9pzhj 1640 2 12 12 CD cord-005646-xhx9pzhj 1640 3 De De NNP cord-005646-xhx9pzhj 1640 4 Octubre Octubre NNP cord-005646-xhx9pzhj 1640 5 . . . cord-005646-xhx9pzhj 1641 1 Madrid Madrid NNP cord-005646-xhx9pzhj 1641 2 . . . cord-005646-xhx9pzhj 1642 1 BACKGROUND background NN cord-005646-xhx9pzhj 1642 2 : : : cord-005646-xhx9pzhj 1643 1 Transesophageal Transesophageal NNP cord-005646-xhx9pzhj 1643 2 pacing pacing NN cord-005646-xhx9pzhj 1643 3 ( ( -LRB- cord-005646-xhx9pzhj 1643 4 TP TP NNP cord-005646-xhx9pzhj 1643 5 ) ) -RRB- cord-005646-xhx9pzhj 1643 6 is be VBZ cord-005646-xhx9pzhj 1643 7 effective effective JJ cord-005646-xhx9pzhj 1643 8 and and CC cord-005646-xhx9pzhj 1643 9 sate sate JJ cord-005646-xhx9pzhj 1643 10 both both DT cord-005646-xhx9pzhj 1643 11 for for IN cord-005646-xhx9pzhj 1643 12 diagnosis diagnosis NN cord-005646-xhx9pzhj 1643 13 and and CC cord-005646-xhx9pzhj 1643 14 treatment treatment NN cord-005646-xhx9pzhj 1643 15 of of IN cord-005646-xhx9pzhj 1643 16 pediatric pediatric JJ cord-005646-xhx9pzhj 1643 17 arrhythmias arrhythmia NNS cord-005646-xhx9pzhj 1643 18 . . . cord-005646-xhx9pzhj 1644 1 MATERIAL material NN cord-005646-xhx9pzhj 1644 2 AND and CC cord-005646-xhx9pzhj 1644 3 METHODS method NNS cord-005646-xhx9pzhj 1644 4 . . . cord-005646-xhx9pzhj 1645 1 Eleven eleven CD cord-005646-xhx9pzhj 1645 2 consecutive consecutive JJ cord-005646-xhx9pzhj 1645 3 patients patient NNS cord-005646-xhx9pzhj 1645 4 are be VBP cord-005646-xhx9pzhj 1645 5 included include VBN cord-005646-xhx9pzhj 1645 6 . . . cord-005646-xhx9pzhj 1646 1 A a DT cord-005646-xhx9pzhj 1646 2 tri tri NN cord-005646-xhx9pzhj 1646 3 or or CC cord-005646-xhx9pzhj 1646 4 quaddpolar quaddpolar NNP cord-005646-xhx9pzhj 1646 5 6 6 CD cord-005646-xhx9pzhj 1646 6 or or CC cord-005646-xhx9pzhj 1646 7 7F 7f CD cord-005646-xhx9pzhj 1646 8 temporal temporal JJ cord-005646-xhx9pzhj 1646 9 transvenous transvenous JJ cord-005646-xhx9pzhj 1646 10 catheter catheter NN cord-005646-xhx9pzhj 1646 11 with with IN cord-005646-xhx9pzhj 1646 12 an an DT cord-005646-xhx9pzhj 1646 13 interpolar interpolar JJ cord-005646-xhx9pzhj 1646 14 distance distance NN cord-005646-xhx9pzhj 1646 15 of of IN cord-005646-xhx9pzhj 1646 16 13 13 CD cord-005646-xhx9pzhj 1646 17 to to TO cord-005646-xhx9pzhj 1646 18 22 22 CD cord-005646-xhx9pzhj 1646 19 mm mm NN cord-005646-xhx9pzhj 1646 20 was be VBD cord-005646-xhx9pzhj 1646 21 advanced advanced JJ cord-005646-xhx9pzhj 1646 22 through through IN cord-005646-xhx9pzhj 1646 23 the the DT cord-005646-xhx9pzhj 1646 24 nares naris NNS cord-005646-xhx9pzhj 1646 25 and and CC cord-005646-xhx9pzhj 1646 26 positioned position VBD cord-005646-xhx9pzhj 1646 27 to to IN cord-005646-xhx9pzhj 1646 28 the the DT cord-005646-xhx9pzhj 1646 29 point point NN cord-005646-xhx9pzhj 1646 30 with with IN cord-005646-xhx9pzhj 1646 31 the the DT cord-005646-xhx9pzhj 1646 32 largest large JJS cord-005646-xhx9pzhj 1646 33 amplitude amplitude NN cord-005646-xhx9pzhj 1646 34 of of IN cord-005646-xhx9pzhj 1646 35 atrial atrial JJ cord-005646-xhx9pzhj 1646 36 deflection deflection NN cord-005646-xhx9pzhj 1646 37 , , , cord-005646-xhx9pzhj 1646 38 Surface Surface NNP cord-005646-xhx9pzhj 1646 39 ECG ECG NNP cord-005646-xhx9pzhj 1646 40 and and CC cord-005646-xhx9pzhj 1646 41 a a DT cord-005646-xhx9pzhj 1646 42 bi bi JJ cord-005646-xhx9pzhj 1646 43 or or CC cord-005646-xhx9pzhj 1646 44 monopolar monopolar JJ cord-005646-xhx9pzhj 1646 45 electregram electregram NNP cord-005646-xhx9pzhj 1646 46 were be VBD cord-005646-xhx9pzhj 1646 47 recorded record VBN cord-005646-xhx9pzhj 1646 48 simultaneously simultaneously RB cord-005646-xhx9pzhj 1646 49 , , , cord-005646-xhx9pzhj 1646 50 selecting select VBG cord-005646-xhx9pzhj 1646 51 filters filter NNS cord-005646-xhx9pzhj 1646 52 when when WRB cord-005646-xhx9pzhj 1646 53 needed need VBN cord-005646-xhx9pzhj 1646 54 ( ( -LRB- cord-005646-xhx9pzhj 1646 55 5 5 CD cord-005646-xhx9pzhj 1646 56 to to TO cord-005646-xhx9pzhj 1646 57 100 100 CD cord-005646-xhx9pzhj 1646 58 MHz MHz NNPS cord-005646-xhx9pzhj 1646 59 ) ) -RRB- cord-005646-xhx9pzhj 1646 60 . . . cord-005646-xhx9pzhj 1647 1 Pacing pace VBG cord-005646-xhx9pzhj 1647 2 was be VBD cord-005646-xhx9pzhj 1647 3 performed perform VBN cord-005646-xhx9pzhj 1647 4 with with IN cord-005646-xhx9pzhj 1647 5 a a DT cord-005646-xhx9pzhj 1647 6 programmable programmable JJ cord-005646-xhx9pzhj 1647 7 stimulator stimulator NN cord-005646-xhx9pzhj 1647 8 ( ( -LRB- cord-005646-xhx9pzhj 1647 9 Medtronic Medtronic NNP cord-005646-xhx9pzhj 1647 10 5328 5328 CD cord-005646-xhx9pzhj 1647 11 ) ) -RRB- cord-005646-xhx9pzhj 1647 12 beginning begin VBG cord-005646-xhx9pzhj 1647 13 with with IN cord-005646-xhx9pzhj 1647 14 2 2 CD cord-005646-xhx9pzhj 1647 15 ms m NNS cord-005646-xhx9pzhj 1647 16 and and CC cord-005646-xhx9pzhj 1647 17 increasing increase VBG cord-005646-xhx9pzhj 1647 18 mA mA NNP cord-005646-xhx9pzhj 1647 19 to to IN cord-005646-xhx9pzhj 1647 20 10 10 CD cord-005646-xhx9pzhj 1647 21 and and CC cord-005646-xhx9pzhj 1647 22 then then RB cord-005646-xhx9pzhj 1647 23 increasing increase VBG cord-005646-xhx9pzhj 1647 24 up up RP cord-005646-xhx9pzhj 1647 25 to to IN cord-005646-xhx9pzhj 1647 26 9.9 9.9 CD cord-005646-xhx9pzhj 1647 27 ms m NNS cord-005646-xhx9pzhj 1647 28 . . . cord-005646-xhx9pzhj 1647 29 Narula Narula NNP cord-005646-xhx9pzhj 1647 30 method method NN cord-005646-xhx9pzhj 1647 31 was be VBD cord-005646-xhx9pzhj 1647 32 selected select VBN cord-005646-xhx9pzhj 1647 33 to to TO cord-005646-xhx9pzhj 1647 34 diagnose diagnose VB cord-005646-xhx9pzhj 1647 35 sinusal sinusal NN cord-005646-xhx9pzhj 1647 36 node node NN cord-005646-xhx9pzhj 1647 37 disfunction disfunction NN cord-005646-xhx9pzhj 1647 38 ( ( -LRB- cord-005646-xhx9pzhj 1647 39 SND SND NNP cord-005646-xhx9pzhj 1647 40 ) ) -RRB- cord-005646-xhx9pzhj 1647 41 and and CC cord-005646-xhx9pzhj 1647 42 overdrive overdrive NN cord-005646-xhx9pzhj 1647 43 pacing pacing NN cord-005646-xhx9pzhj 1647 44 to to TO cord-005646-xhx9pzhj 1647 45 treat treat VB cord-005646-xhx9pzhj 1647 46 tachyarrhythmias tachyarrhythmia NNS cord-005646-xhx9pzhj 1647 47 . . . cord-005646-xhx9pzhj 1648 1 RESULTS result NNS cord-005646-xhx9pzhj 1648 2 . . . cord-005646-xhx9pzhj 1649 1 TP TP NNP cord-005646-xhx9pzhj 1649 2 was be VBD cord-005646-xhx9pzhj 1649 3 useful useful JJ cord-005646-xhx9pzhj 1649 4 in in IN cord-005646-xhx9pzhj 1649 5 all all PDT cord-005646-xhx9pzhj 1649 6 the the DT cord-005646-xhx9pzhj 1649 7 11 11 CD cord-005646-xhx9pzhj 1649 8 patients patient NNS cord-005646-xhx9pzhj 1649 9 and and CC cord-005646-xhx9pzhj 1649 10 no no DT cord-005646-xhx9pzhj 1649 11 complications complication NNS cord-005646-xhx9pzhj 1649 12 were be VBD cord-005646-xhx9pzhj 1649 13 observed observe VBN cord-005646-xhx9pzhj 1649 14 : : : cord-005646-xhx9pzhj 1649 15 in in IN cord-005646-xhx9pzhj 1649 16 3 3 CD cord-005646-xhx9pzhj 1649 17 patients patient NNS cord-005646-xhx9pzhj 1649 18 a a DT cord-005646-xhx9pzhj 1649 19 SND SND NNP cord-005646-xhx9pzhj 1649 20 was be VBD cord-005646-xhx9pzhj 1649 21 diagnosed diagnose VBN cord-005646-xhx9pzhj 1649 22 ( ( -LRB- cord-005646-xhx9pzhj 1649 23 one one CD cord-005646-xhx9pzhj 1649 24 needing need VBG cord-005646-xhx9pzhj 1649 25 a a DT cord-005646-xhx9pzhj 1649 26 definitive definitive JJ cord-005646-xhx9pzhj 1649 27 pacemaker pacemaker NN cord-005646-xhx9pzhj 1649 28 ) ) -RRB- cord-005646-xhx9pzhj 1649 29 , , , cord-005646-xhx9pzhj 1649 30 in in IN cord-005646-xhx9pzhj 1649 31 two two CD cord-005646-xhx9pzhj 1649 32 patients patient NNS cord-005646-xhx9pzhj 1649 33 with with IN cord-005646-xhx9pzhj 1649 34 Atrial Atrial NNP cord-005646-xhx9pzhj 1649 35 Ratter Ratter NNP cord-005646-xhx9pzhj 1649 36 ( ( -LRB- cord-005646-xhx9pzhj 1649 37 ripe ripe JJ cord-005646-xhx9pzhj 1649 38 1 1 CD cord-005646-xhx9pzhj 1649 39 ) ) -RRB- cord-005646-xhx9pzhj 1649 40 sinus sinus NN cord-005646-xhx9pzhj 1649 41 rhythm rhythm NN cord-005646-xhx9pzhj 1649 42 was be VBD cord-005646-xhx9pzhj 1649 43 recovered recover VBN cord-005646-xhx9pzhj 1649 44 , , , cord-005646-xhx9pzhj 1649 45 in in IN cord-005646-xhx9pzhj 1649 46 one one CD cord-005646-xhx9pzhj 1649 47 patient patient NN cord-005646-xhx9pzhj 1649 48 with with IN cord-005646-xhx9pzhj 1649 49 a a DT cord-005646-xhx9pzhj 1649 50 postoperative postoperative JJ cord-005646-xhx9pzhj 1649 51 Junctional Junctional NNP cord-005646-xhx9pzhj 1649 52 Ectopic Ectopic NNP cord-005646-xhx9pzhj 1649 53 Tachycadia Tachycadia NNP cord-005646-xhx9pzhj 1649 54 we -PRON- PRP cord-005646-xhx9pzhj 1649 55 were be VBD cord-005646-xhx9pzhj 1649 56 able able JJ cord-005646-xhx9pzhj 1649 57 to to TO cord-005646-xhx9pzhj 1649 58 get get VB cord-005646-xhx9pzhj 1649 59 atrial atrial JJ cord-005646-xhx9pzhj 1649 60 synchrony synchrony NN cord-005646-xhx9pzhj 1649 61 with with IN cord-005646-xhx9pzhj 1649 62 marked marked JJ cord-005646-xhx9pzhj 1649 63 bemodinamic bemodinamic JJ cord-005646-xhx9pzhj 1649 64 improvement improvement NN cord-005646-xhx9pzhj 1649 65 , , , cord-005646-xhx9pzhj 1649 66 and and CC cord-005646-xhx9pzhj 1649 67 5 5 CD cord-005646-xhx9pzhj 1649 68 patients patient NNS cord-005646-xhx9pzhj 1649 69 with with IN cord-005646-xhx9pzhj 1649 70 Paroxysmal Paroxysmal NNP cord-005646-xhx9pzhj 1649 71 Supraventricular supraventricular JJ cord-005646-xhx9pzhj 1649 72 Tachycardia tachycardia JJ cord-005646-xhx9pzhj 1649 73 sinus sinus NN cord-005646-xhx9pzhj 1649 74 rhythm rhythm NN cord-005646-xhx9pzhj 1649 75 was be VBD cord-005646-xhx9pzhj 1649 76 easily easily RB cord-005646-xhx9pzhj 1649 77 and and CC cord-005646-xhx9pzhj 1649 78 quickly quickly RB cord-005646-xhx9pzhj 1649 79 restored restore VBD cord-005646-xhx9pzhj 1649 80 ( ( -LRB- cord-005646-xhx9pzhj 1649 81 2 2 CD cord-005646-xhx9pzhj 1649 82 of of IN cord-005646-xhx9pzhj 1649 83 them -PRON- PRP cord-005646-xhx9pzhj 1649 84 recquirad recquirad NNP cord-005646-xhx9pzhj 1649 85 repited repite VBD cord-005646-xhx9pzhj 1649 86 episodes episode NNS cord-005646-xhx9pzhj 1649 87 of of IN cord-005646-xhx9pzhj 1649 88 TP TP NNP cord-005646-xhx9pzhj 1649 89 until until IN cord-005646-xhx9pzhj 1649 90 pharmacelogycal pharmacelogycal JJ cord-005646-xhx9pzhj 1649 91 levels level NNS cord-005646-xhx9pzhj 1649 92 of of IN cord-005646-xhx9pzhj 1649 93 antiarrhythmic antiarrhythmic JJ cord-005646-xhx9pzhj 1649 94 drugs drug NNS cord-005646-xhx9pzhj 1649 95 were be VBD cord-005646-xhx9pzhj 1649 96 raised raise VBN cord-005646-xhx9pzhj 1649 97 ) ) -RRB- cord-005646-xhx9pzhj 1649 98 . . . cord-005646-xhx9pzhj 1650 1 Mean mean JJ cord-005646-xhx9pzhj 1650 2 age age NN cord-005646-xhx9pzhj 1650 3 and and CC cord-005646-xhx9pzhj 1650 4 weight weight NN cord-005646-xhx9pzhj 1650 5 were be VBD cord-005646-xhx9pzhj 1650 6 31 31 CD cord-005646-xhx9pzhj 1650 7 months month NNS cord-005646-xhx9pzhj 1650 8 and and CC cord-005646-xhx9pzhj 1650 9 12.7 12.7 CD cord-005646-xhx9pzhj 1650 10 kg kg NNS cord-005646-xhx9pzhj 1650 11 ( ( -LRB- cord-005646-xhx9pzhj 1650 12 one one CD cord-005646-xhx9pzhj 1650 13 patient patient NN cord-005646-xhx9pzhj 1650 14 had have VBD cord-005646-xhx9pzhj 1650 15 2.1 2.1 CD cord-005646-xhx9pzhj 1650 16 kg kg NNS cord-005646-xhx9pzhj 1650 17 ) ) -RRB- cord-005646-xhx9pzhj 1650 18 . . . cord-005646-xhx9pzhj 1651 1 There there EX cord-005646-xhx9pzhj 1651 2 was be VBD cord-005646-xhx9pzhj 1651 3 a a DT cord-005646-xhx9pzhj 1651 4 close close JJ cord-005646-xhx9pzhj 1651 5 relation relation NN cord-005646-xhx9pzhj 1651 6 between between IN cord-005646-xhx9pzhj 1651 7 height height NN cord-005646-xhx9pzhj 1651 8 and and CC cord-005646-xhx9pzhj 1651 9 depht depht NNP cord-005646-xhx9pzhj 1651 10 insertion insertion NN cord-005646-xhx9pzhj 1651 11 ( ( -LRB- cord-005646-xhx9pzhj 1651 12 r= r= NNP cord-005646-xhx9pzhj 1651 13 0.98 0.98 CD cord-005646-xhx9pzhj 1651 14 ) ) -RRB- cord-005646-xhx9pzhj 1651 15 . . . cord-005646-xhx9pzhj 1652 1 Mean mean JJ cord-005646-xhx9pzhj 1652 2 stimulation stimulation NN cord-005646-xhx9pzhj 1652 3 parameters parameter NNS cord-005646-xhx9pzhj 1652 4 were be VBD cord-005646-xhx9pzhj 1652 5 9,1 9,1 CD cord-005646-xhx9pzhj 1652 6 ms m NNS cord-005646-xhx9pzhj 1652 7 and and CC cord-005646-xhx9pzhj 1652 8 13.5 13.5 CD cord-005646-xhx9pzhj 1652 9 mA. mA. NNP cord-005646-xhx9pzhj 1652 10 DISCUSSION DISCUSSION NNP cord-005646-xhx9pzhj 1652 11 . . . cord-005646-xhx9pzhj 1653 1 In in IN cord-005646-xhx9pzhj 1653 2 experiencied experiencied JJ cord-005646-xhx9pzhj 1653 3 hands hand NNS cord-005646-xhx9pzhj 1653 4 TP TP NNP cord-005646-xhx9pzhj 1653 5 is be VBZ cord-005646-xhx9pzhj 1653 6 an an DT cord-005646-xhx9pzhj 1653 7 effective effective JJ cord-005646-xhx9pzhj 1653 8 and and CC cord-005646-xhx9pzhj 1653 9 safe safe JJ cord-005646-xhx9pzhj 1653 10 way way NN cord-005646-xhx9pzhj 1653 11 to to TO cord-005646-xhx9pzhj 1653 12 treat treat VB cord-005646-xhx9pzhj 1653 13 and and CC cord-005646-xhx9pzhj 1653 14 diagnose diagnose VB cord-005646-xhx9pzhj 1653 15 cardiac cardiac JJ cord-005646-xhx9pzhj 1653 16 arrhythmias arrhythmia NNS cord-005646-xhx9pzhj 1653 17 even even RB cord-005646-xhx9pzhj 1653 18 in in IN cord-005646-xhx9pzhj 1653 19 newborns newborn NNS cord-005646-xhx9pzhj 1653 20 . . . cord-005646-xhx9pzhj 1654 1 It -PRON- PRP cord-005646-xhx9pzhj 1654 2 should should MD cord-005646-xhx9pzhj 1654 3 be be VB cord-005646-xhx9pzhj 1654 4 tried try VBN cord-005646-xhx9pzhj 1654 5 before before IN cord-005646-xhx9pzhj 1654 6 endovenous endovenous JJ cord-005646-xhx9pzhj 1654 7 pacing pacing NN cord-005646-xhx9pzhj 1654 8 is be VBZ cord-005646-xhx9pzhj 1654 9 stablished stablishe VBN cord-005646-xhx9pzhj 1654 10 and and CC cord-005646-xhx9pzhj 1654 11 it -PRON- PRP cord-005646-xhx9pzhj 1654 12 is be VBZ cord-005646-xhx9pzhj 1654 13 faster fast JJR cord-005646-xhx9pzhj 1654 14 than than IN cord-005646-xhx9pzhj 1654 15 pharmacologycal pharmacologycal JJ cord-005646-xhx9pzhj 1654 16 treatment treatment NN cord-005646-xhx9pzhj 1654 17 . . . cord-005646-xhx9pzhj 1655 1 Bailing bail VBG cord-005646-xhx9pzhj 1655 2 G. G. NNP cord-005646-xhx9pzhj 1655 3 , , , cord-005646-xhx9pzhj 1655 4 Eicken Eicken NNP cord-005646-xhx9pzhj 1655 5 A. a. NN cord-005646-xhx9pzhj 1655 6 , , , cord-005646-xhx9pzhj 1655 7 Sebening Sebening NNP cord-005646-xhx9pzhj 1655 8 W. W. NNP cord-005646-xhx9pzhj 1655 9 , , , cord-005646-xhx9pzhj 1655 10 Vogt Vogt NNP cord-005646-xhx9pzhj 1655 11 M. M. NNP cord-005646-xhx9pzhj 1655 12 , , , cord-005646-xhx9pzhj 1655 13 Schumacher Schumacher NNP cord-005646-xhx9pzhj 1655 14 G. G. NNP cord-005646-xhx9pzhj 1655 15 , , , cord-005646-xhx9pzhj 1655 16 BL BL NNP cord-005646-xhx9pzhj 1655 17 ~ ~ NFP cord-005646-xhx9pzhj 1655 18 hlmeyer hlmeyer NNP cord-005646-xhx9pzhj 1655 19 K. K. NNP cord-005646-xhx9pzhj 1655 20 ; ; : cord-005646-xhx9pzhj 1655 21 Kinderkardiologie Kinderkardiologie NNP cord-005646-xhx9pzhj 1655 22 , , , cord-005646-xhx9pzhj 1655 23 Deutsches Deutsches NNP cord-005646-xhx9pzhj 1655 24 Herzzentrum Herzzentrum NNP cord-005646-xhx9pzhj 1656 1 M0nchen M0nchen NNP cord-005646-xhx9pzhj 1656 2 , , , cord-005646-xhx9pzhj 1656 3 Germany Germany NNP cord-005646-xhx9pzhj 1657 1 To to TO cord-005646-xhx9pzhj 1657 2 assess assess VB cord-005646-xhx9pzhj 1657 3 the the DT cord-005646-xhx9pzhj 1657 4 outcome outcome NN cord-005646-xhx9pzhj 1657 5 of of IN cord-005646-xhx9pzhj 1657 6 balloon balloon NN cord-005646-xhx9pzhj 1657 7 valvuloplasty valvuloplasty NN cord-005646-xhx9pzhj 1657 8 in in IN cord-005646-xhx9pzhj 1657 9 infants infant NNS cord-005646-xhx9pzhj 1657 10 with with IN cord-005646-xhx9pzhj 1657 11 cardiac cardiac JJ cord-005646-xhx9pzhj 1657 12 failure failure NN cord-005646-xhx9pzhj 1657 13 caused cause VBN cord-005646-xhx9pzhj 1657 14 by by IN cord-005646-xhx9pzhj 1657 15 critical critical JJ cord-005646-xhx9pzhj 1657 16 aortic aortic JJ cord-005646-xhx9pzhj 1657 17 stenosis stenosis NN cord-005646-xhx9pzhj 1657 18 a a DT cord-005646-xhx9pzhj 1657 19 retrospective retrospective JJ cord-005646-xhx9pzhj 1657 20 study study NN cord-005646-xhx9pzhj 1657 21 was be VBD cord-005646-xhx9pzhj 1657 22 performed perform VBN cord-005646-xhx9pzhj 1657 23 . . . cord-005646-xhx9pzhj 1658 1 Between between IN cord-005646-xhx9pzhj 1658 2 1986 1986 CD cord-005646-xhx9pzhj 1658 3 and and CC cord-005646-xhx9pzhj 1658 4 1995 1995 CD cord-005646-xhx9pzhj 1658 5 33 33 CD cord-005646-xhx9pzhj 1658 6 neonates neonate NNS cord-005646-xhx9pzhj 1658 7 , , , cord-005646-xhx9pzhj 1658 8 aged aged JJ cord-005646-xhx9pzhj 1658 9 1 1 CD cord-005646-xhx9pzhj 1658 10 -28 -28 NN cord-005646-xhx9pzhj 1658 11 days day NNS cord-005646-xhx9pzhj 1658 12 ( ( -LRB- cord-005646-xhx9pzhj 1658 13 median median JJ cord-005646-xhx9pzhj 1658 14 9 9 CD cord-005646-xhx9pzhj 1658 15 d d NN cord-005646-xhx9pzhj 1658 16 ) ) -RRB- cord-005646-xhx9pzhj 1658 17 , , , cord-005646-xhx9pzhj 1658 18 weight weight NN cord-005646-xhx9pzhj 1658 19 2.t 2.t CD cord-005646-xhx9pzhj 1658 20 -4,1 -4,1 HYPH cord-005646-xhx9pzhj 1658 21 kg kg NNP cord-005646-xhx9pzhj 1658 22 ( ( -LRB- cord-005646-xhx9pzhj 1658 23 median median NN cord-005646-xhx9pzhj 1658 24 3,3 3,3 CD cord-005646-xhx9pzhj 1658 25 kg kg NNP cord-005646-xhx9pzhj 1658 26 ) ) -RRB- cord-005646-xhx9pzhj 1658 27 with with IN cord-005646-xhx9pzhj 1658 28 critical critical JJ cord-005646-xhx9pzhj 1658 29 valvar valvar NNP cord-005646-xhx9pzhj 1658 30 aortic aortic JJ cord-005646-xhx9pzhj 1658 31 stenosis stenosis NN cord-005646-xhx9pzhj 1658 32 were be VBD cord-005646-xhx9pzhj 1658 33 dilated dilate VBN cord-005646-xhx9pzhj 1658 34 by by IN cord-005646-xhx9pzhj 1658 35 balloon balloon NN cord-005646-xhx9pzhj 1658 36 ( ( -LRB- cord-005646-xhx9pzhj 1658 37 AoVP AoVP NNP cord-005646-xhx9pzhj 1658 38 ) ) -RRB- cord-005646-xhx9pzhj 1658 39 as as IN cord-005646-xhx9pzhj 1658 40 the the DT cord-005646-xhx9pzhj 1658 41 first first JJ cord-005646-xhx9pzhj 1658 42 line line NN cord-005646-xhx9pzhj 1658 43 treatment treatment NN cord-005646-xhx9pzhj 1658 44 . . . cord-005646-xhx9pzhj 1659 1 21 21 CD cord-005646-xhx9pzhj 1659 2 patients patient NNS cord-005646-xhx9pzhj 1659 3 received receive VBD cord-005646-xhx9pzhj 1659 4 Prostaglandin Prostaglandin NNP cord-005646-xhx9pzhj 1659 5 El El NNP cord-005646-xhx9pzhj 1659 6 , , , cord-005646-xhx9pzhj 1659 7 18 18 CD cord-005646-xhx9pzhj 1659 8 needed need VBD cord-005646-xhx9pzhj 1659 9 inotropic inotropic NNP cord-005646-xhx9pzhj 1659 10 drugs drug NNS cord-005646-xhx9pzhj 1659 11 and and CC cord-005646-xhx9pzhj 1659 12 16 16 CD cord-005646-xhx9pzhj 1659 13 mechanical mechanical JJ cord-005646-xhx9pzhj 1659 14 ventilation ventilation NN cord-005646-xhx9pzhj 1659 15 . . . cord-005646-xhx9pzhj 1660 1 Associated associated JJ cord-005646-xhx9pzhj 1660 2 cardiac cardiac NN cord-005646-xhx9pzhj 1660 3 lesions lesion NNS cord-005646-xhx9pzhj 1660 4 : : : cord-005646-xhx9pzhj 1660 5 Persistent persistent JJ cord-005646-xhx9pzhj 1660 6 ductus ductus NN cord-005646-xhx9pzhj 1660 7 arteriosus arteriosus NN cord-005646-xhx9pzhj 1660 8 ( ( -LRB- cord-005646-xhx9pzhj 1660 9 PDA PDA NNP cord-005646-xhx9pzhj 1660 10 ) ) -RRB- cord-005646-xhx9pzhj 1660 11 in in IN cord-005646-xhx9pzhj 1660 12 27 27 CD cord-005646-xhx9pzhj 1660 13 patients patient NNS cord-005646-xhx9pzhj 1660 14 ( ( -LRB- cord-005646-xhx9pzhj 1660 15 restrictive restrictive JJ cord-005646-xhx9pzhj 1660 16 PDA pda NN cord-005646-xhx9pzhj 1660 17 in in IN cord-005646-xhx9pzhj 1660 18 8 8 CD cord-005646-xhx9pzhj 1660 19 cases case NNS cord-005646-xhx9pzhj 1660 20 ) ) -RRB- cord-005646-xhx9pzhj 1660 21 , , , cord-005646-xhx9pzhj 1660 22 a a DT cord-005646-xhx9pzhj 1660 23 mitral mitral JJ cord-005646-xhx9pzhj 1660 24 regurgitation regurgitation NN cord-005646-xhx9pzhj 1660 25 ( ( -LRB- cord-005646-xhx9pzhj 1660 26 MiVR MiVR NNP cord-005646-xhx9pzhj 1660 27 ) ) -RRB- cord-005646-xhx9pzhj 1660 28 in in IN cord-005646-xhx9pzhj 1660 29 27 27 CD cord-005646-xhx9pzhj 1660 30 cases case NNS cord-005646-xhx9pzhj 1660 31 ( ( -LRB- cord-005646-xhx9pzhj 1660 32 15 15 CD cord-005646-xhx9pzhj 1660 33 severe severe JJ cord-005646-xhx9pzhj 1660 34 and and CC cord-005646-xhx9pzhj 1660 35 12 12 CD cord-005646-xhx9pzhj 1660 36 moderate moderate JJ cord-005646-xhx9pzhj 1660 37 or or CC cord-005646-xhx9pzhj 1660 38 mild mild JJ cord-005646-xhx9pzhj 1660 39 MiVR MiVR NNP cord-005646-xhx9pzhj 1660 40 ) ) -RRB- cord-005646-xhx9pzhj 1660 41 , , , cord-005646-xhx9pzhj 1660 42 angiographic angiographic JJ cord-005646-xhx9pzhj 1660 43 findings finding NNS cord-005646-xhx9pzhj 1660 44 of of IN cord-005646-xhx9pzhj 1660 45 endocardial endocardial NNP cord-005646-xhx9pzhj 1660 46 fibroelastosis fibroelastosis NNP cord-005646-xhx9pzhj 1660 47 ( ( -LRB- cord-005646-xhx9pzhj 1660 48 EFE EFE NNP cord-005646-xhx9pzhj 1660 49 ) ) -RRB- cord-005646-xhx9pzhj 1660 50 in in IN cord-005646-xhx9pzhj 1660 51 12 12 CD cord-005646-xhx9pzhj 1660 52 patients patient NNS cord-005646-xhx9pzhj 1660 53 , , , cord-005646-xhx9pzhj 1660 54 mitral mitral JJ cord-005646-xhx9pzhj 1660 55 stenosis stenosis NN cord-005646-xhx9pzhj 1660 56 ( ( -LRB- cord-005646-xhx9pzhj 1660 57 MiVS MiVS NNP cord-005646-xhx9pzhj 1660 58 ) ) -RRB- cord-005646-xhx9pzhj 1660 59 in in IN cord-005646-xhx9pzhj 1660 60 8 8 CD cord-005646-xhx9pzhj 1660 61 , , , cord-005646-xhx9pzhj 1660 62 coarctation coarctation NN cord-005646-xhx9pzhj 1660 63 of of IN cord-005646-xhx9pzhj 1660 64 the the DT cord-005646-xhx9pzhj 1660 65 aorta aorta NNP cord-005646-xhx9pzhj 1660 66 ( ( -LRB- cord-005646-xhx9pzhj 1660 67 CoA CoA NNP cord-005646-xhx9pzhj 1660 68 ) ) -RRB- cord-005646-xhx9pzhj 1660 69 in in IN cord-005646-xhx9pzhj 1660 70 2 2 CD cord-005646-xhx9pzhj 1660 71 , , , cord-005646-xhx9pzhj 1660 72 and and CC cord-005646-xhx9pzhj 1660 73 finally finally RB cord-005646-xhx9pzhj 1660 74 a a DT cord-005646-xhx9pzhj 1660 75 small small JJ cord-005646-xhx9pzhj 1660 76 musculary musculary JJ cord-005646-xhx9pzhj 1660 77 ventricular ventricular JJ cord-005646-xhx9pzhj 1660 78 septum septum NN cord-005646-xhx9pzhj 1660 79 defect defect NN cord-005646-xhx9pzhj 1660 80 ( ( -LRB- cord-005646-xhx9pzhj 1660 81 VSD VSD NNP cord-005646-xhx9pzhj 1660 82 ) ) -RRB- cord-005646-xhx9pzhj 1660 83 in in IN cord-005646-xhx9pzhj 1660 84 I -PRON- PRP cord-005646-xhx9pzhj 1660 85 patient patient JJ cord-005646-xhx9pzhj 1660 86 . . . cord-005646-xhx9pzhj 1661 1 Vascular vascular JJ cord-005646-xhx9pzhj 1661 2 approach approach NN cord-005646-xhx9pzhj 1661 3 for for IN cord-005646-xhx9pzhj 1661 4 ballooning ballooning NN cord-005646-xhx9pzhj 1661 5 : : : cord-005646-xhx9pzhj 1662 1 A. a. LS cord-005646-xhx9pzhj 1662 2 axitfaris axitfaris NNP cord-005646-xhx9pzhj 1662 3 in in IN cord-005646-xhx9pzhj 1662 4 20 20 CD cord-005646-xhx9pzhj 1662 5 cases case NNS cord-005646-xhx9pzhj 1662 6 ( ( -LRB- cord-005646-xhx9pzhj 1662 7 61 61 CD cord-005646-xhx9pzhj 1662 8 % % NN cord-005646-xhx9pzhj 1662 9 ) ) -RRB- cord-005646-xhx9pzhj 1662 10 a. a. NN cord-005646-xhx9pzhj 1662 11 femoralis femoralis NNP cord-005646-xhx9pzhj 1662 12 in in IN cord-005646-xhx9pzhj 1662 13 t t NNP cord-005646-xhx9pzhj 1662 14 0 0 CD cord-005646-xhx9pzhj 1662 15 ( ( -LRB- cord-005646-xhx9pzhj 1662 16 30 30 CD cord-005646-xhx9pzhj 1662 17 % % NN cord-005646-xhx9pzhj 1662 18 ) ) -RRB- cord-005646-xhx9pzhj 1662 19 and and CC cord-005646-xhx9pzhj 1662 20 v. v. IN cord-005646-xhx9pzhj 1662 21 femoralis femoralis NNP cord-005646-xhx9pzhj 1662 22 in in IN cord-005646-xhx9pzhj 1662 23 3 3 CD cord-005646-xhx9pzhj 1662 24 cases case NNS cord-005646-xhx9pzhj 1662 25 ( ( -LRB- cord-005646-xhx9pzhj 1662 26 9 9 CD cord-005646-xhx9pzhj 1662 27 % % NN cord-005646-xhx9pzhj 1662 28 ) ) -RRB- cord-005646-xhx9pzhj 1662 29 . . . cord-005646-xhx9pzhj 1663 1 The the DT cord-005646-xhx9pzhj 1663 2 median median JJ cord-005646-xhx9pzhj 1663 3 ratio ratio NN cord-005646-xhx9pzhj 1663 4 between between IN cord-005646-xhx9pzhj 1663 5 inflated inflated JJ cord-005646-xhx9pzhj 1663 6 balloon balloon NN cord-005646-xhx9pzhj 1663 7 and and CC cord-005646-xhx9pzhj 1663 8 aortic aortic JJ cord-005646-xhx9pzhj 1663 9 valve valve NN cord-005646-xhx9pzhj 1663 10 diameter diameter NN cord-005646-xhx9pzhj 1663 11 was be VBD cord-005646-xhx9pzhj 1663 12 0,99 0,99 XX cord-005646-xhx9pzhj 1663 13 . . . cord-005646-xhx9pzhj 1664 1 Dilatation Dilatation NNP cord-005646-xhx9pzhj 1664 2 was be VBD cord-005646-xhx9pzhj 1664 3 achieved achieve VBN cord-005646-xhx9pzhj 1664 4 in in IN cord-005646-xhx9pzhj 1664 5 all all DT cord-005646-xhx9pzhj 1664 6 33 33 CD cord-005646-xhx9pzhj 1664 7 cases case NNS cord-005646-xhx9pzhj 1664 8 . . . cord-005646-xhx9pzhj 1665 1 The the DT cord-005646-xhx9pzhj 1665 2 peak peak JJ cord-005646-xhx9pzhj 1665 3 systolic systolic JJ cord-005646-xhx9pzhj 1665 4 gradient gradient NN cord-005646-xhx9pzhj 1665 5 across across IN cord-005646-xhx9pzhj 1665 6 the the DT cord-005646-xhx9pzhj 1665 7 aortic aortic JJ cord-005646-xhx9pzhj 1665 8 valve valve NN cord-005646-xhx9pzhj 1665 9 ( ( -LRB- cord-005646-xhx9pzhj 1665 10 pre pre JJ cord-005646-xhx9pzhj 1665 11 AoVP AoVP NNP cord-005646-xhx9pzhj 1665 12 ) ) -RRB- cord-005646-xhx9pzhj 1665 13 ranged range VBD cord-005646-xhx9pzhj 1665 14 from from IN cord-005646-xhx9pzhj 1665 15 0 0 CD cord-005646-xhx9pzhj 1665 16 to to IN cord-005646-xhx9pzhj 1665 17 137 137 CD cord-005646-xhx9pzhj 1665 18 mmHg mmHg NNS cord-005646-xhx9pzhj 1665 19 ( ( -LRB- cord-005646-xhx9pzhj 1665 20 median median NN cord-005646-xhx9pzhj 1665 21 50 50 CD cord-005646-xhx9pzhj 1665 22 mmHg mmHg NNS cord-005646-xhx9pzhj 1665 23 ) ) -RRB- cord-005646-xhx9pzhj 1665 24 and and CC cord-005646-xhx9pzhj 1665 25 was be VBD cord-005646-xhx9pzhj 1665 26 reduced reduce VBN cord-005646-xhx9pzhj 1665 27 to to IN cord-005646-xhx9pzhj 1665 28 0 0 CD cord-005646-xhx9pzhj 1665 29 to to IN cord-005646-xhx9pzhj 1665 30 55 55 CD cord-005646-xhx9pzhj 1665 31 mmHg mmHg NNS cord-005646-xhx9pzhj 1665 32 ( ( -LRB- cord-005646-xhx9pzhj 1665 33 median median NN cord-005646-xhx9pzhj 1665 34 15 15 CD cord-005646-xhx9pzhj 1665 35 ; ; : cord-005646-xhx9pzhj 1665 36 gradient gradient NN cord-005646-xhx9pzhj 1665 37 reduction reduction NN cord-005646-xhx9pzhj 1665 38 is be VBZ cord-005646-xhx9pzhj 1665 39 significant significant JJ cord-005646-xhx9pzhj 1665 40 ( ( -LRB- cord-005646-xhx9pzhj 1665 41 p p NN cord-005646-xhx9pzhj 1665 42 < < XX cord-005646-xhx9pzhj 1665 43 0,01 0,01 NN cord-005646-xhx9pzhj 1665 44 ) ) -RRB- cord-005646-xhx9pzhj 1665 45 ) ) -RRB- cord-005646-xhx9pzhj 1665 46 . . . cord-005646-xhx9pzhj 1666 1 Aortic aortic JJ cord-005646-xhx9pzhj 1666 2 regurgitation regurgitation NN cord-005646-xhx9pzhj 1666 3 ( ( -LRB- cord-005646-xhx9pzhj 1666 4 AoVR AoVR NNP cord-005646-xhx9pzhj 1666 5 ) ) -RRB- cord-005646-xhx9pzhj 1666 6 was be VBD cord-005646-xhx9pzhj 1666 7 absent absent JJ cord-005646-xhx9pzhj 1666 8 or or CC cord-005646-xhx9pzhj 1666 9 mild mild JJ cord-005646-xhx9pzhj 1666 10 in in IN cord-005646-xhx9pzhj 1666 11 30 30 CD cord-005646-xhx9pzhj 1666 12 , , , cord-005646-xhx9pzhj 1666 13 moderate moderate JJ cord-005646-xhx9pzhj 1666 14 in in IN cord-005646-xhx9pzhj 1666 15 2 2 CD cord-005646-xhx9pzhj 1666 16 and and CC cord-005646-xhx9pzhj 1666 17 severe severe JJ cord-005646-xhx9pzhj 1666 18 in in IN cord-005646-xhx9pzhj 1666 19 1 1 CD cord-005646-xhx9pzhj 1666 20 patient patient NN cord-005646-xhx9pzhj 1666 21 after after IN cord-005646-xhx9pzhj 1666 22 AoVP AoVP NNP cord-005646-xhx9pzhj 1666 23 . . . cord-005646-xhx9pzhj 1667 1 23 23 CD cord-005646-xhx9pzhj 1667 2 children child NNS cord-005646-xhx9pzhj 1667 3 survived survive VBD cord-005646-xhx9pzhj 1667 4 ( ( -LRB- cord-005646-xhx9pzhj 1667 5 actual actual JJ cord-005646-xhx9pzhj 1667 6 suwival suwival JJ cord-005646-xhx9pzhj 1667 7 rate rate NN cord-005646-xhx9pzhj 1667 8 : : : cord-005646-xhx9pzhj 1667 9 70 70 CD cord-005646-xhx9pzhj 1667 10 % % NN cord-005646-xhx9pzhj 1667 11 ; ; , cord-005646-xhx9pzhj 1667 12 early early JJ cord-005646-xhx9pzhj 1667 13 mortalffy mortalffy NNP cord-005646-xhx9pzhj 1667 14 : : : cord-005646-xhx9pzhj 1667 15 n n NN cord-005646-xhx9pzhj 1667 16 = = SYM cord-005646-xhx9pzhj 1667 17 3 3 CD cord-005646-xhx9pzhj 1667 18 ; ; , cord-005646-xhx9pzhj 1667 19 late late JJ cord-005646-xhx9pzhj 1667 20 mortality mortality NN cord-005646-xhx9pzhj 1667 21 : : : cord-005646-xhx9pzhj 1667 22 n n NN cord-005646-xhx9pzhj 1667 23 = = SYM cord-005646-xhx9pzhj 1667 24 7 7 CD cord-005646-xhx9pzhj 1667 25 ) ) -RRB- cord-005646-xhx9pzhj 1667 26 . . . cord-005646-xhx9pzhj 1668 1 Mid mid JJ cord-005646-xhx9pzhj 1668 2 term term NN cord-005646-xhx9pzhj 1668 3 follow follow VB cord-005646-xhx9pzhj 1668 4 up up RP cord-005646-xhx9pzhj 1668 5 ( ( -LRB- cord-005646-xhx9pzhj 1668 6 0 0 CD cord-005646-xhx9pzhj 1668 7 - - HYPH cord-005646-xhx9pzhj 1668 8 8,8 8,8 CD cord-005646-xhx9pzhj 1668 9 years year NNS cord-005646-xhx9pzhj 1668 10 ; ; : cord-005646-xhx9pzhj 1668 11 mean mean VB cord-005646-xhx9pzhj 1668 12 2,7 2,7 CD cord-005646-xhx9pzhj 1668 13 years year NNS cord-005646-xhx9pzhj 1668 14 ) ) -RRB- cord-005646-xhx9pzhj 1668 15 showed show VBD cord-005646-xhx9pzhj 1668 16 an an DT cord-005646-xhx9pzhj 1668 17 increase increase NN cord-005646-xhx9pzhj 1668 18 of of IN cord-005646-xhx9pzhj 1668 19 the the DT cord-005646-xhx9pzhj 1668 20 systolic systolic JJ cord-005646-xhx9pzhj 1668 21 peak peak NN cord-005646-xhx9pzhj 1668 22 doppler doppler NN cord-005646-xhx9pzhj 1668 23 gradient gradient NN cord-005646-xhx9pzhj 1668 24 across across IN cord-005646-xhx9pzhj 1668 25 the the DT cord-005646-xhx9pzhj 1668 26 aortic aortic JJ cord-005646-xhx9pzhj 1668 27 valve valve NN cord-005646-xhx9pzhj 1668 28 ( ( -LRB- cord-005646-xhx9pzhj 1668 29 median median NN cord-005646-xhx9pzhj 1668 30 41 41 CD cord-005646-xhx9pzhj 1668 31 mmHg mmHg NNS cord-005646-xhx9pzhj 1668 32 ) ) -RRB- cord-005646-xhx9pzhj 1668 33 but but CC cord-005646-xhx9pzhj 1668 34 no no DT cord-005646-xhx9pzhj 1668 35 increase increase NN cord-005646-xhx9pzhj 1668 36 of of IN cord-005646-xhx9pzhj 1668 37 AoVR aovr NN cord-005646-xhx9pzhj 1668 38 . . . cord-005646-xhx9pzhj 1669 1 10 10 CD cord-005646-xhx9pzhj 1669 2 re re NNS cord-005646-xhx9pzhj 1669 3 - - NNS cord-005646-xhx9pzhj 1669 4 interventions intervention NNS cord-005646-xhx9pzhj 1669 5 ( ( -LRB- cord-005646-xhx9pzhj 1669 6 Re re NN cord-005646-xhx9pzhj 1669 7 - - NN cord-005646-xhx9pzhj 1669 8 AoVP aovp NN cord-005646-xhx9pzhj 1669 9 : : : cord-005646-xhx9pzhj 1669 10 n n NN cord-005646-xhx9pzhj 1669 11 = = SYM cord-005646-xhx9pzhj 1669 12 3 3 CD cord-005646-xhx9pzhj 1669 13 , , , cord-005646-xhx9pzhj 1669 14 commissurotomy commissurotomy NNP cord-005646-xhx9pzhj 1669 15 : : : cord-005646-xhx9pzhj 1670 1 n n NN cord-005646-xhx9pzhj 1670 2 = = SYM cord-005646-xhx9pzhj 1670 3 2 2 CD cord-005646-xhx9pzhj 1670 4 , , , cord-005646-xhx9pzhj 1670 5 mitral mitral JJ cord-005646-xhx9pzhj 1670 6 valve valve NN cord-005646-xhx9pzhj 1670 7 replacement replacement NN cord-005646-xhx9pzhj 1670 8 n n NN cord-005646-xhx9pzhj 1670 9 = = SYM cord-005646-xhx9pzhj 1670 10 2 2 CD cord-005646-xhx9pzhj 1670 11 , , , cord-005646-xhx9pzhj 1670 12 resection resection NN cord-005646-xhx9pzhj 1670 13 of of IN cord-005646-xhx9pzhj 1670 14 subaortic subaortic JJ cord-005646-xhx9pzhj 1670 15 stenosis stenosis NN cord-005646-xhx9pzhj 1670 16 : : : cord-005646-xhx9pzhj 1670 17 n n NN cord-005646-xhx9pzhj 1670 18 = = SYM cord-005646-xhx9pzhj 1670 19 1 1 CD cord-005646-xhx9pzhj 1670 20 , , , cord-005646-xhx9pzhj 1670 21 resection resection NN cord-005646-xhx9pzhj 1670 22 of of IN cord-005646-xhx9pzhj 1670 23 coarctation coarctation NN cord-005646-xhx9pzhj 1671 1 : : : cord-005646-xhx9pzhj 1671 2 n n NN cord-005646-xhx9pzhj 1671 3 = = SYM cord-005646-xhx9pzhj 1671 4 2,VSD 2,vsd CD cord-005646-xhx9pzhj 1671 5 - - HYPH cord-005646-xhx9pzhj 1671 6 closura closura NNP cord-005646-xhx9pzhj 1671 7 : : : cord-005646-xhx9pzhj 1672 1 n n NN cord-005646-xhx9pzhj 1672 2 = = SYM cord-005646-xhx9pzhj 1672 3 1 1 CD cord-005646-xhx9pzhj 1672 4 ) ) -RRB- cord-005646-xhx9pzhj 1672 5 were be VBD cord-005646-xhx9pzhj 1672 6 performed perform VBN cord-005646-xhx9pzhj 1672 7 in in IN cord-005646-xhx9pzhj 1672 8 6 6 CD cord-005646-xhx9pzhj 1672 9 patients patient NNS cord-005646-xhx9pzhj 1672 10 . . . cord-005646-xhx9pzhj 1673 1 RV rv NN cord-005646-xhx9pzhj 1673 2 contractility contractility NN cord-005646-xhx9pzhj 1673 3 and and CC cord-005646-xhx9pzhj 1673 4 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1673 5 vascular vascular JJ cord-005646-xhx9pzhj 1673 6 mechanics(PVM mechanics(pvm NN cord-005646-xhx9pzhj 1673 7 ) ) -RRB- cord-005646-xhx9pzhj 1673 8 in in IN cord-005646-xhx9pzhj 1673 9 immature immature JJ cord-005646-xhx9pzhj 1673 10 animal animal NN cord-005646-xhx9pzhj 1673 11 models model NNS cord-005646-xhx9pzhj 1673 12 are be VBP cord-005646-xhx9pzhj 1673 13 poorly poorly RB cord-005646-xhx9pzhj 1673 14 underslood underslood JJ cord-005646-xhx9pzhj 1673 15 . . . cord-005646-xhx9pzhj 1674 1 We -PRON- PRP cord-005646-xhx9pzhj 1674 2 developed develop VBD cord-005646-xhx9pzhj 1674 3 an an DT cord-005646-xhx9pzhj 1674 4 acute acute JJ cord-005646-xhx9pzhj 1674 5 RV RV NNP cord-005646-xhx9pzhj 1674 6 injury injury NN cord-005646-xhx9pzhj 1674 7 model model NN cord-005646-xhx9pzhj 1674 8 to to TO cord-005646-xhx9pzhj 1674 9 measure measure VB cord-005646-xhx9pzhj 1674 10 RV rv NN cord-005646-xhx9pzhj 1674 11 contractility contractility NN cord-005646-xhx9pzhj 1674 12 and and CC cord-005646-xhx9pzhj 1674 13 PVM PVM NNP cord-005646-xhx9pzhj 1674 14 in in IN cord-005646-xhx9pzhj 1674 15 response response NN cord-005646-xhx9pzhj 1674 16 to to TO cord-005646-xhx9pzhj 1674 17 commonly commonly RB cord-005646-xhx9pzhj 1674 18 used use VBN cord-005646-xhx9pzhj 1674 19 cateehalamines cateehalamine NNS cord-005646-xhx9pzhj 1674 20 . . . cord-005646-xhx9pzhj 1675 1 Ten ten CD cord-005646-xhx9pzhj 1675 2 anesthetized anesthetized JJ cord-005646-xhx9pzhj 1675 3 piglets piglet NNS cord-005646-xhx9pzhj 1675 4 ( ( -LRB- cord-005646-xhx9pzhj 1675 5 9 9 CD cord-005646-xhx9pzhj 1675 6 - - SYM cord-005646-xhx9pzhj 1675 7 12 12 CD cord-005646-xhx9pzhj 1675 8 kg kg NNS cord-005646-xhx9pzhj 1675 9 ) ) -RRB- cord-005646-xhx9pzhj 1675 10 were be VBD cord-005646-xhx9pzhj 1675 11 instrumented instrument VBN cord-005646-xhx9pzhj 1675 12 with with IN cord-005646-xhx9pzhj 1675 13 micromanometers micromanometer NNS cord-005646-xhx9pzhj 1675 14 in in IN cord-005646-xhx9pzhj 1675 15 the the DT cord-005646-xhx9pzhj 1675 16 LV LV NNP cord-005646-xhx9pzhj 1675 17 , , , cord-005646-xhx9pzhj 1675 18 RV RV NNP cord-005646-xhx9pzhj 1675 19 , , , cord-005646-xhx9pzhj 1675 20 PA PA NNP cord-005646-xhx9pzhj 1675 21 , , , cord-005646-xhx9pzhj 1675 22 and and CC cord-005646-xhx9pzhj 1675 23 LA LA NNP cord-005646-xhx9pzhj 1675 24 . . . cord-005646-xhx9pzhj 1676 1 A a DT cord-005646-xhx9pzhj 1676 2 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1676 3 artery artery NN cord-005646-xhx9pzhj 1676 4 flow flow NN cord-005646-xhx9pzhj 1676 5 probe probe NN cord-005646-xhx9pzhj 1676 6 was be VBD cord-005646-xhx9pzhj 1676 7 placed place VBN cord-005646-xhx9pzhj 1676 8 to to TO cord-005646-xhx9pzhj 1676 9 measure measure VB cord-005646-xhx9pzhj 1676 10 cardiac cardiac JJ cord-005646-xhx9pzhj 1676 11 output(Qpa output(qpa NN cord-005646-xhx9pzhj 1676 12 ) ) -RRB- cord-005646-xhx9pzhj 1676 13 . . . cord-005646-xhx9pzhj 1677 1 Ultrasonic ultrasonic JJ cord-005646-xhx9pzhj 1677 2 dimension dimension NN cord-005646-xhx9pzhj 1677 3 crystals crystal NNS cord-005646-xhx9pzhj 1677 4 were be VBD cord-005646-xhx9pzhj 1677 5 sutured suture VBN cord-005646-xhx9pzhj 1677 6 to to IN cord-005646-xhx9pzhj 1677 7 the the DT cord-005646-xhx9pzhj 1677 8 myocardium myocardium NN cord-005646-xhx9pzhj 1677 9 and and CC cord-005646-xhx9pzhj 1677 10 dynamic dynamic JJ cord-005646-xhx9pzhj 1677 11 chamber chamber NN cord-005646-xhx9pzhj 1677 12 volumes volume NNS cord-005646-xhx9pzhj 1677 13 estimated estimate VBN cord-005646-xhx9pzhj 1677 14 using use VBG cord-005646-xhx9pzhj 1677 15 shell shell NN cord-005646-xhx9pzhj 1677 16 subtraction subtraction NN cord-005646-xhx9pzhj 1677 17 methodology methodology NN cord-005646-xhx9pzhj 1677 18 . . . cord-005646-xhx9pzhj 1678 1 RV RV NNP cord-005646-xhx9pzhj 1678 2 injury injury NN cord-005646-xhx9pzhj 1678 3 was be VBD cord-005646-xhx9pzhj 1678 4 induced induce VBN cord-005646-xhx9pzhj 1678 5 with with IN cord-005646-xhx9pzhj 1678 6 3 3 CD cord-005646-xhx9pzhj 1678 7 - - SYM cord-005646-xhx9pzhj 1678 8 7 7 CD cord-005646-xhx9pzhj 1678 9 cryoprobe cryoprobe NN cord-005646-xhx9pzhj 1678 10 injuries injury NNS cord-005646-xhx9pzhj 1678 11 at at IN cord-005646-xhx9pzhj 1678 12 -50 -50 NN cord-005646-xhx9pzhj 1678 13 to to IN cord-005646-xhx9pzhj 1678 14 -70 -70 NN cord-005646-xhx9pzhj 1678 15 ° ° NN cord-005646-xhx9pzhj 1678 16 C c NN cord-005646-xhx9pzhj 1678 17 for for IN cord-005646-xhx9pzhj 1678 18 3 3 CD cord-005646-xhx9pzhj 1678 19 - - SYM cord-005646-xhx9pzhj 1678 20 4 4 CD cord-005646-xhx9pzhj 1678 21 minmes minme NNS cord-005646-xhx9pzhj 1678 22 each each DT cord-005646-xhx9pzhj 1678 23 . . . cord-005646-xhx9pzhj 1679 1 DA DA NNP cord-005646-xhx9pzhj 1679 2 at at IN cord-005646-xhx9pzhj 1679 3 10mg 10mg NNP cord-005646-xhx9pzhj 1679 4 / / SYM cord-005646-xhx9pzhj 1679 5 kg kg NNP cord-005646-xhx9pzhj 1679 6 / / SYM cord-005646-xhx9pzhj 1679 7 min min NNP cord-005646-xhx9pzhj 1679 8 , , , cord-005646-xhx9pzhj 1679 9 DB DB NNP cord-005646-xhx9pzhj 1679 10 at at IN cord-005646-xhx9pzhj 1679 11 10mg 10mg NNP cord-005646-xhx9pzhj 1679 12 / / SYM cord-005646-xhx9pzhj 1679 13 kg kg NNP cord-005646-xhx9pzhj 1679 14 / / SYM cord-005646-xhx9pzhj 1679 15 min min NNP cord-005646-xhx9pzhj 1679 16 , , , cord-005646-xhx9pzhj 1679 17 and and CC cord-005646-xhx9pzhj 1679 18 EP EP NNP cord-005646-xhx9pzhj 1679 19 at at IN cord-005646-xhx9pzhj 1679 20 0.1 0.1 CD cord-005646-xhx9pzhj 1679 21 mg mg NNP cord-005646-xhx9pzhj 1679 22 / / SYM cord-005646-xhx9pzhj 1679 23 kg kg NNP cord-005646-xhx9pzhj 1679 24 / / SYM cord-005646-xhx9pzhj 1679 25 min min NNP cord-005646-xhx9pzhj 1679 26 were be VBD cord-005646-xhx9pzhj 1679 27 infused infuse VBN cord-005646-xhx9pzhj 1679 28 in in IN cord-005646-xhx9pzhj 1679 29 random random JJ cord-005646-xhx9pzhj 1679 30 order order NN cord-005646-xhx9pzhj 1679 31 . . . cord-005646-xhx9pzhj 1680 1 RV rv NN cord-005646-xhx9pzhj 1680 2 contractility contractility NN cord-005646-xhx9pzhj 1680 3 was be VBD cord-005646-xhx9pzhj 1680 4 evaluated evaluate VBN cord-005646-xhx9pzhj 1680 5 by by IN cord-005646-xhx9pzhj 1680 6 calculating calculate VBG cord-005646-xhx9pzhj 1680 7 a a DT cord-005646-xhx9pzhj 1680 8 load load NN cord-005646-xhx9pzhj 1680 9 independent independent JJ cord-005646-xhx9pzhj 1680 10 measure measure NN cord-005646-xhx9pzhj 1680 11 of of IN cord-005646-xhx9pzhj 1680 12 contractility contractility NN cord-005646-xhx9pzhj 1680 13 , , , cord-005646-xhx9pzhj 1680 14 the the DT cord-005646-xhx9pzhj 1680 15 preload preload NNP cord-005646-xhx9pzhj 1680 16 recmitable recmitable NNP cord-005646-xhx9pzhj 1680 17 stroke stroke NNP cord-005646-xhx9pzhj 1680 18 work(PRSW work(prsw ADD cord-005646-xhx9pzhj 1680 19 ) ) -RRB- cord-005646-xhx9pzhj 1680 20 , , , cord-005646-xhx9pzhj 1680 21 during during IN cord-005646-xhx9pzhj 1680 22 vena vena NNP cord-005646-xhx9pzhj 1680 23 caval caval NNP cord-005646-xhx9pzhj 1680 24 occlusions occlusion NNS cord-005646-xhx9pzhj 1680 25 . . . cord-005646-xhx9pzhj 1681 1 To to TO cord-005646-xhx9pzhj 1681 2 describe describe VB cord-005646-xhx9pzhj 1681 3 PVM PVM NNP cord-005646-xhx9pzhj 1681 4 , , , cord-005646-xhx9pzhj 1681 5 input input NN cord-005646-xhx9pzhj 1681 6 resistanceS resistanceS NNP cord-005646-xhx9pzhj 1681 7 ) ) -RRB- cord-005646-xhx9pzhj 1681 8 , , , cord-005646-xhx9pzhj 1681 9 characteristic characteristic JJ cord-005646-xhx9pzhj 1681 10 impedance(Z0 impedance(Z0 NNP cord-005646-xhx9pzhj 1681 11 ) ) -RRB- cord-005646-xhx9pzhj 1681 12 , , , cord-005646-xhx9pzhj 1681 13 total total JJ cord-005646-xhx9pzhj 1681 14 pewer(TP pewer(TP NNP cord-005646-xhx9pzhj 1681 15 ) ) -RRB- cord-005646-xhx9pzhj 1681 16 , , , cord-005646-xhx9pzhj 1681 17 and and CC cord-005646-xhx9pzhj 1681 18 efficieacy efficieacy NN cord-005646-xhx9pzhj 1681 19 03f 03f . cord-005646-xhx9pzhj 1682 1 = = NFP cord-005646-xhx9pzhj 1683 1 QimO"P QimO"P NNP cord-005646-xhx9pzhj 1683 2 ) ) -RRB- cord-005646-xhx9pzhj 1683 3 were be VBD cord-005646-xhx9pzhj 1683 4 measured measure VBN cord-005646-xhx9pzhj 1683 5 . . . cord-005646-xhx9pzhj 1684 1 Measurements measurement NNS cord-005646-xhx9pzhj 1684 2 were be VBD cord-005646-xhx9pzhj 1684 3 made make VBN cord-005646-xhx9pzhj 1684 4 pre pre JJ cord-005646-xhx9pzhj 1684 5 - - JJ cord-005646-xhx9pzhj 1684 6 and and CC cord-005646-xhx9pzhj 1684 7 post post JJ cord-005646-xhx9pzhj 1684 8 - - JJ cord-005646-xhx9pzhj 1684 9 injury injury NN cord-005646-xhx9pzhj 1684 10 , , , cord-005646-xhx9pzhj 1684 11 during during IN cord-005646-xhx9pzhj 1684 12 infusions infusion NNS cord-005646-xhx9pzhj 1684 13 , , , cord-005646-xhx9pzhj 1684 14 and and CC cord-005646-xhx9pzhj 1684 15 between between IN cord-005646-xhx9pzhj 1684 16 infusions infusion NNS cord-005646-xhx9pzhj 1684 17 . . . cord-005646-xhx9pzhj 1685 1 Clyoablation Clyoablation NNP cord-005646-xhx9pzhj 1685 2 decreased decrease VBD cord-005646-xhx9pzhj 1685 3 PRSW PRSW NNP cord-005646-xhx9pzhj 1685 4 ( ( -LRB- cord-005646-xhx9pzhj 1685 5 22.8_+7.8 22.8_+7.8 CD cord-005646-xhx9pzhj 1685 6 to to IN cord-005646-xhx9pzhj 1685 7 13.8 13.8 CD cord-005646-xhx9pzhj 1685 8 + + SYM cord-005646-xhx9pzhj 1685 9 4.1 4.1 CD cord-005646-xhx9pzhj 1685 10 , , , cord-005646-xhx9pzhj 1685 11 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 1685 12 ) ) -RRB- cord-005646-xhx9pzhj 1685 13 . . . cord-005646-xhx9pzhj 1686 1 At at IN cord-005646-xhx9pzhj 1686 2 the the DT cord-005646-xhx9pzhj 1686 3 end end NN cord-005646-xhx9pzhj 1686 4 of of IN cord-005646-xhx9pzhj 1686 5 the the DT cord-005646-xhx9pzhj 1686 6 experiment experiment NN cord-005646-xhx9pzhj 1686 7 , , , cord-005646-xhx9pzhj 1686 8 PRSW PRSW NNP cord-005646-xhx9pzhj 1686 9 remained remain VBD cord-005646-xhx9pzhj 1686 10 depressed depressed JJ cord-005646-xhx9pzhj 1686 11 to to IN cord-005646-xhx9pzhj 1686 12 this this DT cord-005646-xhx9pzhj 1686 13 level level NN cord-005646-xhx9pzhj 1686 14 indicating indicate VBG cord-005646-xhx9pzhj 1686 15 stability stability NN cord-005646-xhx9pzhj 1686 16 of of IN cord-005646-xhx9pzhj 1686 17 the the DT cord-005646-xhx9pzhj 1686 18 model model NN cord-005646-xhx9pzhj 1686 19 . . . cord-005646-xhx9pzhj 1687 1 One one CD cord-005646-xhx9pzhj 1687 2 factor factor NN cord-005646-xhx9pzhj 1687 3 contributing contribute VBG cord-005646-xhx9pzhj 1687 4 to to IN cord-005646-xhx9pzhj 1687 5 organ organ NN cord-005646-xhx9pzhj 1687 6 dysfunction dysfunction NN cord-005646-xhx9pzhj 1687 7 for for IN cord-005646-xhx9pzhj 1687 8 infants infant NNS cord-005646-xhx9pzhj 1687 9 undergoing undergo VBG cord-005646-xhx9pzhj 1687 10 repair repair NN cord-005646-xhx9pzhj 1687 11 of of IN cord-005646-xhx9pzhj 1687 12 congenital congenital JJ cord-005646-xhx9pzhj 1687 13 heart heart NN cord-005646-xhx9pzhj 1687 14 defects defect NNS cord-005646-xhx9pzhj 1687 15 ( ( -LRB- cord-005646-xhx9pzhj 1687 16 CHD CHD NNP cord-005646-xhx9pzhj 1687 17 ) ) -RRB- cord-005646-xhx9pzhj 1687 18 is be VBZ cord-005646-xhx9pzhj 1687 19 their -PRON- PRP$ cord-005646-xhx9pzhj 1687 20 " " `` cord-005646-xhx9pzhj 1687 21 inflammatory inflammatory JJ cord-005646-xhx9pzhj 1687 22 response response NN cord-005646-xhx9pzhj 1687 23 " " '' cord-005646-xhx9pzhj 1687 24 to to IN cord-005646-xhx9pzhj 1687 25 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 1687 26 bypass bypass NN cord-005646-xhx9pzhj 1687 27 ( ( -LRB- cord-005646-xhx9pzhj 1687 28 CPB CPB NNP cord-005646-xhx9pzhj 1687 29 ) ) -RRB- cord-005646-xhx9pzhj 1687 30 . . . cord-005646-xhx9pzhj 1688 1 This this DT cord-005646-xhx9pzhj 1688 2 response response NN cord-005646-xhx9pzhj 1688 3 is be VBZ cord-005646-xhx9pzhj 1688 4 characterized characterize VBN cord-005646-xhx9pzhj 1688 5 by by IN cord-005646-xhx9pzhj 1688 6 an an DT cord-005646-xhx9pzhj 1688 7 increase increase NN cord-005646-xhx9pzhj 1688 8 in in IN cord-005646-xhx9pzhj 1688 9 cytokine cytokine NN cord-005646-xhx9pzhj 1688 10 release release NN cord-005646-xhx9pzhj 1688 11 , , , cord-005646-xhx9pzhj 1688 12 complement complement JJ cord-005646-xhx9pzhj 1688 13 activation activation NN cord-005646-xhx9pzhj 1688 14 and and CC cord-005646-xhx9pzhj 1688 15 endothelial endothelial JJ cord-005646-xhx9pzhj 1688 16 injury injury NN cord-005646-xhx9pzhj 1688 17 . . . cord-005646-xhx9pzhj 1689 1 Modified modify VBN cord-005646-xhx9pzhj 1689 2 ultrafiltration ultrafiltration NN cord-005646-xhx9pzhj 1689 3 ( ( -LRB- cord-005646-xhx9pzhj 1689 4 MUF MUF NNP cord-005646-xhx9pzhj 1689 5 ) ) -RRB- cord-005646-xhx9pzhj 1689 6 is be VBZ cord-005646-xhx9pzhj 1689 7 a a DT cord-005646-xhx9pzhj 1689 8 method method NN cord-005646-xhx9pzhj 1689 9 for for IN cord-005646-xhx9pzhj 1689 10 removing remove VBG cord-005646-xhx9pzhj 1689 11 tissue tissue NN cord-005646-xhx9pzhj 1689 12 water water NN cord-005646-xhx9pzhj 1689 13 and and CC cord-005646-xhx9pzhj 1689 14 inflammatory inflammatory JJ cord-005646-xhx9pzhj 1689 15 mediators mediator NNS cord-005646-xhx9pzhj 1689 16 by by IN cord-005646-xhx9pzhj 1689 17 rapid rapid JJ cord-005646-xhx9pzhj 1689 18 ultrafiltration ultrafiltration NNP cord-005646-xhx9pzhj 1689 19 followin~ followin~ NNP cord-005646-xhx9pzhj 1689 20 CPB CPB NNP cord-005646-xhx9pzhj 1689 21 , , , cord-005646-xhx9pzhj 1689 22 MUF MUF NNP cord-005646-xhx9pzhj 1689 23 may may MD cord-005646-xhx9pzhj 1689 24 acutely acutely RB cord-005646-xhx9pzhj 1689 25 improve improve VB cord-005646-xhx9pzhj 1689 26 post post JJ cord-005646-xhx9pzhj 1689 27 - - JJ cord-005646-xhx9pzhj 1689 28 operative operative JJ cord-005646-xhx9pzhj 1689 29 end end NN cord-005646-xhx9pzhj 1689 30 organ organ NN cord-005646-xhx9pzhj 1689 31 function function NN cord-005646-xhx9pzhj 1689 32 . . . cord-005646-xhx9pzhj 1690 1 In in IN cord-005646-xhx9pzhj 1690 2 this this DT cord-005646-xhx9pzhj 1690 3 study study NN cord-005646-xhx9pzhj 1690 4 , , , cord-005646-xhx9pzhj 1690 5 we -PRON- PRP cord-005646-xhx9pzhj 1690 6 evaluated evaluate VBD cord-005646-xhx9pzhj 1690 7 the the DT cord-005646-xhx9pzhj 1690 8 effects effect NNS cord-005646-xhx9pzhj 1690 9 of of IN cord-005646-xhx9pzhj 1690 10 MUF MUF NNP cord-005646-xhx9pzhj 1690 11 on on IN cord-005646-xhx9pzhj 1690 12 the the DT cord-005646-xhx9pzhj 1690 13 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1690 14 and and CC cord-005646-xhx9pzhj 1690 15 cerebral cerebral JJ cord-005646-xhx9pzhj 1690 16 function function NN cord-005646-xhx9pzhj 1690 17 of of IN cord-005646-xhx9pzhj 1690 18 infants infant NNS cord-005646-xhx9pzhj 1690 19 undergoing undergo VBG cord-005646-xhx9pzhj 1690 20 CPB CPB NNP cord-005646-xhx9pzhj 1690 21 for for IN cord-005646-xhx9pzhj 1690 22 repair repair NN cord-005646-xhx9pzhj 1690 23 of of IN cord-005646-xhx9pzhj 1690 24 CHD CHD NNP cord-005646-xhx9pzhj 1690 25 . . . cord-005646-xhx9pzhj 1691 1 We -PRON- PRP cord-005646-xhx9pzhj 1691 2 prosnecrivety prosnecrivety NN cord-005646-xhx9pzhj 1691 3 randomized randomize VBD cord-005646-xhx9pzhj 1691 4 30 30 CD cord-005646-xhx9pzhj 1691 5 infants infant NNS cord-005646-xhx9pzhj 1691 6 ( ( -LRB- cord-005646-xhx9pzhj 1691 7 .~ .~ . cord-005646-xhx9pzhj 1691 8 5 5 CD cord-005646-xhx9pzhj 1691 9 mos mos NN cord-005646-xhx9pzhj 1691 10 ) ) -RRB- cord-005646-xhx9pzhj 1691 11 to to IN cord-005646-xhx9pzhj 1691 12 either either CC cord-005646-xhx9pzhj 1691 13 MUF MUF NNP cord-005646-xhx9pzhj 1691 14 ( ( -LRB- cord-005646-xhx9pzhj 1691 15 n=16 n=16 NNP cord-005646-xhx9pzhj 1691 16 ) ) -RRB- cord-005646-xhx9pzhj 1691 17 or or CC cord-005646-xhx9pzhj 1691 18 no no DT cord-005646-xhx9pzhj 1691 19 MUF MUF NNP cord-005646-xhx9pzhj 1691 20 ( ( -LRB- cord-005646-xhx9pzhj 1691 21 n=14)(Control n=14)(control NN cord-005646-xhx9pzhj 1691 22 ) ) -RRB- cord-005646-xhx9pzhj 1691 23 following follow VBG cord-005646-xhx9pzhj 1691 24 correction correction NN cord-005646-xhx9pzhj 1691 25 for for IN cord-005646-xhx9pzhj 1691 26 CHD CHD NNP cord-005646-xhx9pzhj 1691 27 . . . cord-005646-xhx9pzhj 1692 1 The the DT cord-005646-xhx9pzhj 1692 2 study study NN cord-005646-xhx9pzhj 1692 3 intervals interval NNS cord-005646-xhx9pzhj 1692 4 were be VBD cord-005646-xhx9pzhj 1692 5 1 1 CD cord-005646-xhx9pzhj 1692 6 ) ) -RRB- cord-005646-xhx9pzhj 1692 7 before before IN cord-005646-xhx9pzhj 1692 8 CPB CPB NNP cord-005646-xhx9pzhj 1692 9 , , , cord-005646-xhx9pzhj 1692 10 2 2 CD cord-005646-xhx9pzhj 1692 11 ) ) -RRB- cord-005646-xhx9pzhj 1692 12 immediately immediately RB cord-005646-xhx9pzhj 1692 13 after after IN cord-005646-xhx9pzhj 1692 14 CPB CPB NNP cord-005646-xhx9pzhj 1692 15 , , , cord-005646-xhx9pzhj 1692 16 and and CC cord-005646-xhx9pzhj 1692 17 3 3 CD cord-005646-xhx9pzhj 1692 18 ) ) -RRB- cord-005646-xhx9pzhj 1692 19 20minutes 20minute NNS cord-005646-xhx9pzhj 1692 20 after after IN cord-005646-xhx9pzhj 1692 21 CPB CPB NNP cord-005646-xhx9pzhj 1692 22 . . . cord-005646-xhx9pzhj 1693 1 Pulmonary pulmonary JJ cord-005646-xhx9pzhj 1693 2 function function NN cord-005646-xhx9pzhj 1693 3 was be VBD cord-005646-xhx9pzhj 1693 4 evaluated evaluate VBN cord-005646-xhx9pzhj 1693 5 by by IN cord-005646-xhx9pzhj 1693 6 measuring measure VBG cord-005646-xhx9pzhj 1693 7 dynamic dynamic JJ cord-005646-xhx9pzhj 1693 8 compliance compliance NN cord-005646-xhx9pzhj 1693 9 ( ( -LRB- cord-005646-xhx9pzhj 1693 10 Cdyn Cdyn NNP cord-005646-xhx9pzhj 1693 11 ) ) -RRB- cord-005646-xhx9pzhj 1693 12 and and CC cord-005646-xhx9pzhj 1693 13 airway airway NN cord-005646-xhx9pzhj 1693 14 resistance resistance NN cord-005646-xhx9pzhj 1693 15 ( ( -LRB- cord-005646-xhx9pzhj 1693 16 Raw Raw NNP cord-005646-xhx9pzhj 1693 17 ) ) -RRB- cord-005646-xhx9pzhj 1693 18 . . . cord-005646-xhx9pzhj 1694 1 For for IN cord-005646-xhx9pzhj 1694 2 13 13 CD cord-005646-xhx9pzhj 1694 3 pts pt NNS cord-005646-xhx9pzhj 1694 4 ( ( -LRB- cord-005646-xhx9pzhj 1694 5 MUE=6 MUE=6 NNP cord-005646-xhx9pzhj 1694 6 pts pts NNP cord-005646-xhx9pzhj 1694 7 ; ; : cord-005646-xhx9pzhj 1694 8 Control=7 Control=7 NNP cord-005646-xhx9pzhj 1694 9 pts pt NNS cord-005646-xhx9pzhj 1694 10 ) ) -RRB- cord-005646-xhx9pzhj 1694 11 exposed expose VBN cord-005646-xhx9pzhj 1694 12 to to IN cord-005646-xhx9pzhj 1694 13 a a DT cord-005646-xhx9pzhj 1694 14 period period NN cord-005646-xhx9pzhj 1694 15 of of IN cord-005646-xhx9pzhj 1694 16 deep deep JJ cord-005646-xhx9pzhj 1694 17 hypothermie hypothermie NNP cord-005646-xhx9pzhj 1694 18 circulatory circulatory JJ cord-005646-xhx9pzhj 1694 19 arrest arrest NN cord-005646-xhx9pzhj 1694 20 ( ( -LRB- cord-005646-xhx9pzhj 1694 21 DHCA DHCA NNP cord-005646-xhx9pzhj 1694 22 ) ) -RRB- cord-005646-xhx9pzhj 1694 23 , , , cord-005646-xhx9pzhj 1694 24 cerebral cerebral JJ cord-005646-xhx9pzhj 1694 25 metabolism metabolism NN cord-005646-xhx9pzhj 1694 26 ( ( -LRB- cord-005646-xhx9pzhj 1694 27 CMRO2 CMRO2 NNP cord-005646-xhx9pzhj 1694 28 ) ) -RRB- cord-005646-xhx9pzhj 1694 29 was be VBD cord-005646-xhx9pzhj 1694 30 calculated calculate VBN cord-005646-xhx9pzhj 1694 31 at at IN cord-005646-xhx9pzhj 1694 32 each each DT cord-005646-xhx9pzhj 1694 33 interval interval NN cord-005646-xhx9pzhj 1694 34 using use VBG cord-005646-xhx9pzhj 1694 35 the the DT cord-005646-xhx9pzhj 1694 36 Xe Xe NNP cord-005646-xhx9pzhj 1694 37 133 133 CD cord-005646-xhx9pzhj 1694 38 clearance clearance NN cord-005646-xhx9pzhj 1694 39 technique technique NN cord-005646-xhx9pzhj 1694 40 for for IN cord-005646-xhx9pzhj 1694 41 cerebral cerebral JJ cord-005646-xhx9pzhj 1694 42 blood blood NN cord-005646-xhx9pzhj 1694 43 flow flow NN cord-005646-xhx9pzhj 1694 44 measurements measurement NNS cord-005646-xhx9pzhj 1694 45 and and CC cord-005646-xhx9pzhj 1694 46 arterial arterial JJ cord-005646-xhx9pzhj 1694 47 and and CC cord-005646-xhx9pzhj 1694 48 jugular jugular NN cord-005646-xhx9pzhj 1694 49 bulb bulb NN cord-005646-xhx9pzhj 1694 50 saturation saturation NN cord-005646-xhx9pzhj 1694 51 measurements measurement NNS cord-005646-xhx9pzhj 1694 52 to to TO cord-005646-xhx9pzhj 1694 53 calculate calculate VB cord-005646-xhx9pzhj 1694 54 CMRO2 CMRO2 NNS cord-005646-xhx9pzhj 1694 55 . . . cord-005646-xhx9pzhj 1695 1 A a DT cord-005646-xhx9pzhj 1695 2 reduction reduction NN cord-005646-xhx9pzhj 1695 3 in in IN cord-005646-xhx9pzhj 1695 4 CMRO2 cmro2 NN cord-005646-xhx9pzhj 1695 5 has have VBZ cord-005646-xhx9pzhj 1695 6 been be VBN cord-005646-xhx9pzhj 1695 7 consistently consistently RB cord-005646-xhx9pzhj 1695 8 demonstrated demonstrate VBN cord-005646-xhx9pzhj 1695 9 after after IN cord-005646-xhx9pzhj 1695 10 DHCA DHCA NNP cord-005646-xhx9pzhj 1695 11 . . . cord-005646-xhx9pzhj 1696 1 The the DT cord-005646-xhx9pzhj 1696 2 effects effect NNS cord-005646-xhx9pzhj 1696 3 of of IN cord-005646-xhx9pzhj 1696 4 MUF MUF NNP cord-005646-xhx9pzhj 1696 5 on on IN cord-005646-xhx9pzhj 1696 6 Cdyn Cdyn NNP cord-005646-xhx9pzhj 1696 7 and and CC cord-005646-xhx9pzhj 1696 8 on on IN cord-005646-xhx9pzhj 1696 9 CMRO2 CMRO2 NNS cord-005646-xhx9pzhj 1696 10 are be VBP cord-005646-xhx9pzhj 1696 11 shown show VBN cord-005646-xhx9pzhj 1696 12 below below RB cord-005646-xhx9pzhj 1696 13 : : : cord-005646-xhx9pzhj 1696 14 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1697 1 vs vs IN cord-005646-xhx9pzhj 1697 2 pre pre NNP cord-005646-xhx9pzhj 1697 3 - - NNP cord-005646-xhx9pzhj 1697 4 CPB CPB NNP cord-005646-xhx9pzhj 1697 5 ; ; : cord-005646-xhx9pzhj 1698 1 # # $ cord-005646-xhx9pzhj 1698 2 p<0.05 p<0.05 NN cord-005646-xhx9pzhj 1698 3 vs vs IN cord-005646-xhx9pzhj 1698 4 post post JJ cord-005646-xhx9pzhj 1698 5 - - JJ cord-005646-xhx9pzhj 1698 6 CPB CPB NNP cord-005646-xhx9pzhj 1698 7 • • NNP cord-005646-xhx9pzhj 1698 8 p-- p-- . cord-005646-xhx9pzhj 1699 1 O.06 O.06 NNP cord-005646-xhx9pzhj 1699 2 vs. vs. IN cord-005646-xhx9pzhj 1700 1 post post NNP cord-005646-xhx9pzhj 1700 2 - - NNP cord-005646-xhx9pzhj 1700 3 CPB CPB NNP cord-005646-xhx9pzhj 1700 4 This this DT cord-005646-xhx9pzhj 1700 5 study study NN cord-005646-xhx9pzhj 1700 6 demonstrates demonstrate VBZ cord-005646-xhx9pzhj 1700 7 that that IN cord-005646-xhx9pzhj 1700 8 immediately immediately RB cord-005646-xhx9pzhj 1700 9 following follow VBG cord-005646-xhx9pzhj 1700 10 exposure exposure NN cord-005646-xhx9pzhj 1700 11 to to IN cord-005646-xhx9pzhj 1700 12 CPB CPB NNP cord-005646-xhx9pzhj 1700 13 , , , cord-005646-xhx9pzhj 1700 14 MUF MUF NNP cord-005646-xhx9pzhj 1700 15 will will MD cord-005646-xhx9pzhj 1700 16 improve improve VB cord-005646-xhx9pzhj 1700 17 pulmonary pulmonary JJ cord-005646-xhx9pzhj 1700 18 compliance compliance NN cord-005646-xhx9pzhj 1700 19 . . . cord-005646-xhx9pzhj 1701 1 Raw Raw NNP cord-005646-xhx9pzhj 1701 2 was be VBD cord-005646-xhx9pzhj 1701 3 not not RB cord-005646-xhx9pzhj 1701 4 different different JJ cord-005646-xhx9pzhj 1701 5 between between IN cord-005646-xhx9pzhj 1701 6 groups group NNS cord-005646-xhx9pzhj 1701 7 . . . cord-005646-xhx9pzhj 1702 1 There there EX cord-005646-xhx9pzhj 1702 2 was be VBD cord-005646-xhx9pzhj 1702 3 no no DT cord-005646-xhx9pzhj 1702 4 significant significant JJ cord-005646-xhx9pzhj 1702 5 difference difference NN cord-005646-xhx9pzhj 1702 6 in in IN cord-005646-xhx9pzhj 1702 7 hours hour NNS cord-005646-xhx9pzhj 1702 8 of of IN cord-005646-xhx9pzhj 1702 9 post post JJ cord-005646-xhx9pzhj 1702 10 - - JJ cord-005646-xhx9pzhj 1702 11 op op JJ cord-005646-xhx9pzhj 1702 12 ventilation ventilation NN cord-005646-xhx9pzhj 1702 13 for for IN cord-005646-xhx9pzhj 1702 14 either either DT cord-005646-xhx9pzhj 1702 15 group group NN cord-005646-xhx9pzhj 1702 16 . . . cord-005646-xhx9pzhj 1703 1 In in IN cord-005646-xhx9pzhj 1703 2 those those DT cord-005646-xhx9pzhj 1703 3 pts pt NNS cord-005646-xhx9pzhj 1703 4 exposed expose VBN cord-005646-xhx9pzhj 1703 5 to to IN cord-005646-xhx9pzhj 1703 6 DHCA DHCA NNP cord-005646-xhx9pzhj 1703 7 a a DT cord-005646-xhx9pzhj 1703 8 trend trend NN cord-005646-xhx9pzhj 1703 9 towards towards IN cord-005646-xhx9pzhj 1703 10 better well JJR cord-005646-xhx9pzhj 1703 11 cerebral cerebral JJ cord-005646-xhx9pzhj 1703 12 metabolic metabolic JJ cord-005646-xhx9pzhj 1703 13 recovery recovery NN cord-005646-xhx9pzhj 1703 14 compared compare VBN cord-005646-xhx9pzhj 1703 15 to to IN cord-005646-xhx9pzhj 1703 16 control control NN cord-005646-xhx9pzhj 1703 17 was be VBD cord-005646-xhx9pzhj 1703 18 demonstrated demonstrate VBN cord-005646-xhx9pzhj 1703 19 . . . cord-005646-xhx9pzhj 1704 1 This this DT cord-005646-xhx9pzhj 1704 2 is be VBZ cord-005646-xhx9pzhj 1704 3 the the DT cord-005646-xhx9pzhj 1704 4 first first JJ cord-005646-xhx9pzhj 1704 5 technique technique NN cord-005646-xhx9pzhj 1704 6 applied apply VBN cord-005646-xhx9pzhj 1704 7 to to IN cord-005646-xhx9pzhj 1704 8 infants infant NNS cord-005646-xhx9pzhj 1704 9 undergoing undergo VBG cord-005646-xhx9pzhj 1704 10 DHCA DHCA NNP cord-005646-xhx9pzhj 1704 11 where where WRB cord-005646-xhx9pzhj 1704 12 CMRO2 CMRO2 NNS cord-005646-xhx9pzhj 1705 1 after after IN cord-005646-xhx9pzhj 1705 2 CPB CPB NNP cord-005646-xhx9pzhj 1705 3 was be VBD cord-005646-xhx9pzhj 1705 4 greater great JJR cord-005646-xhx9pzhj 1705 5 than than IN cord-005646-xhx9pzhj 1705 6 preCPB preCPB NNP cord-005646-xhx9pzhj 1705 7 measm measm NNP cord-005646-xhx9pzhj 1706 1 ~s ~s NNP cord-005646-xhx9pzhj 1706 2 . . . cord-005646-xhx9pzhj 1707 1 Although although IN cord-005646-xhx9pzhj 1707 2 this this DT cord-005646-xhx9pzhj 1707 3 may may MD cord-005646-xhx9pzhj 1707 4 be be VB cord-005646-xhx9pzhj 1707 5 beneficial beneficial JJ cord-005646-xhx9pzhj 1707 6 to to IN cord-005646-xhx9pzhj 1707 7 postoperative postoperative JJ cord-005646-xhx9pzhj 1707 8 hemodynamics hemodynamic NNS cord-005646-xhx9pzhj 1707 9 , , , cord-005646-xhx9pzhj 1707 10 ventilatory ventilatory JJ cord-005646-xhx9pzhj 1707 11 management management NN cord-005646-xhx9pzhj 1707 12 and and CC cord-005646-xhx9pzhj 1707 13 long long JJ cord-005646-xhx9pzhj 1707 14 - - HYPH cord-005646-xhx9pzhj 1707 15 term term NN cord-005646-xhx9pzhj 1707 16 neurologic neurologic JJ cord-005646-xhx9pzhj 1707 17 recovery recovery NN cord-005646-xhx9pzhj 1707 18 , , , cord-005646-xhx9pzhj 1707 19 more more JJR cord-005646-xhx9pzhj 1707 20 patients patient NNS cord-005646-xhx9pzhj 1707 21 and and CC cord-005646-xhx9pzhj 1707 22 longer longer RB cord-005646-xhx9pzhj 1707 23 follow follow VB cord-005646-xhx9pzhj 1707 24 up up RP cord-005646-xhx9pzhj 1707 25 will will MD cord-005646-xhx9pzhj 1707 26 be be VB cord-005646-xhx9pzhj 1707 27 necessary necessary JJ cord-005646-xhx9pzhj 1707 28 to to TO cord-005646-xhx9pzhj 1707 29 verify verify VB cord-005646-xhx9pzhj 1707 30 such such PDT cord-005646-xhx9pzhj 1707 31 an an DT cord-005646-xhx9pzhj 1707 32 effect effect NN cord-005646-xhx9pzhj 1707 33 . . . cord-005646-xhx9pzhj 1708 1 The the DT cord-005646-xhx9pzhj 1708 2 effects effect NNS cord-005646-xhx9pzhj 1708 3 of of IN cord-005646-xhx9pzhj 1708 4 conventional conventional JJ cord-005646-xhx9pzhj 1708 5 mechanical mechanical JJ cord-005646-xhx9pzhj 1708 6 ventilation ventilation NN cord-005646-xhx9pzhj 1708 7 ( ( -LRB- cord-005646-xhx9pzhj 1708 8 CMV CMV NNP cord-005646-xhx9pzhj 1708 9 ) ) -RRB- cord-005646-xhx9pzhj 1708 10 on on IN cord-005646-xhx9pzhj 1708 11 left leave VBN cord-005646-xhx9pzhj 1708 12 ventricular ventricular JJ cord-005646-xhx9pzhj 1708 13 ( ( -LRB- cord-005646-xhx9pzhj 1708 14 LV LV NNP cord-005646-xhx9pzhj 1708 15 ) ) -RRB- cord-005646-xhx9pzhj 1708 16 . . . cord-005646-xhx9pzhj 1709 1 diastolic diastolic JJ cord-005646-xhx9pzhj 1709 2 filling filling NN cord-005646-xhx9pzhj 1709 3 in in RP cord-005646-xhx9pzhj 1709 4 neonates neonate NNS cord-005646-xhx9pzhj 1709 5 are be VBP cord-005646-xhx9pzhj 1709 6 not not RB cord-005646-xhx9pzhj 1709 7 well well RB cord-005646-xhx9pzhj 1709 8 established establish VBN cord-005646-xhx9pzhj 1709 9 . . . cord-005646-xhx9pzhj 1710 1 One one CD cord-005646-xhx9pzhj 1710 2 approach approach NN cord-005646-xhx9pzhj 1710 3 to to TO cord-005646-xhx9pzhj 1710 4 improve improve VB cord-005646-xhx9pzhj 1710 5 LV LV NNP cord-005646-xhx9pzhj 1710 6 filling filling NN cord-005646-xhx9pzhj 1710 7 is be VBZ cord-005646-xhx9pzhj 1710 8 the the DT cord-005646-xhx9pzhj 1710 9 use use NN cord-005646-xhx9pzhj 1710 10 of of IN cord-005646-xhx9pzhj 1710 11 CMV CMV NNP cord-005646-xhx9pzhj 1710 12 to to TO cord-005646-xhx9pzhj 1710 13 provide provide VB cord-005646-xhx9pzhj 1710 14 a a DT cord-005646-xhx9pzhj 1710 15 phasic phasic JJ cord-005646-xhx9pzhj 1710 16 increase increase NN cord-005646-xhx9pzhj 1710 17 in in IN cord-005646-xhx9pzhj 1710 18 airway airway NN cord-005646-xhx9pzhj 1710 19 pressure pressure NN cord-005646-xhx9pzhj 1710 20 { { -LRB- cord-005646-xhx9pzhj 1710 21 thoracic thoracic JJ cord-005646-xhx9pzhj 1710 22 augmentation augmentation NN cord-005646-xhx9pzhj 1710 23 ) ) -RRB- cord-005646-xhx9pzhj 1710 24 . . . cord-005646-xhx9pzhj 1711 1 This this DT cord-005646-xhx9pzhj 1711 2 phasic phasic JJ cord-005646-xhx9pzhj 1711 3 increase increase NN cord-005646-xhx9pzhj 1711 4 in in IN cord-005646-xhx9pzhj 1711 5 airway airway NN cord-005646-xhx9pzhj 1711 6 pressure pressure NN cord-005646-xhx9pzhj 1711 7 may may MD cord-005646-xhx9pzhj 1711 8 result result VB cord-005646-xhx9pzhj 1711 9 in in IN cord-005646-xhx9pzhj 1711 10 an an DT cord-005646-xhx9pzhj 1711 11 increase increase NN cord-005646-xhx9pzhj 1711 12 in in IN cord-005646-xhx9pzhj 1711 13 LV LV NNP cord-005646-xhx9pzhj 1711 14 filling fill VBG cord-005646-xhx9pzhj 1711 15 similar similar JJ cord-005646-xhx9pzhj 1711 16 to to IN cord-005646-xhx9pzhj 1711 17 that that DT cord-005646-xhx9pzhj 1711 18 which which WDT cord-005646-xhx9pzhj 1711 19 occurs occur VBZ cord-005646-xhx9pzhj 1711 20 with with IN cord-005646-xhx9pzhj 1711 21 CPR CPR NNP cord-005646-xhx9pzhj 1711 22 . . . cord-005646-xhx9pzhj 1712 1 Thoracic thoracic JJ cord-005646-xhx9pzhj 1712 2 augmentation augmentation NN cord-005646-xhx9pzhj 1712 3 has have VBZ cord-005646-xhx9pzhj 1712 4 not not RB cord-005646-xhx9pzhj 1712 5 been be VBN cord-005646-xhx9pzhj 1712 6 evaluated evaluate VBN cord-005646-xhx9pzhj 1712 7 in in IN cord-005646-xhx9pzhj 1712 8 neonates neonate NNS cord-005646-xhx9pzhj 1712 9 with with IN cord-005646-xhx9pzhj 1712 10 ventricular ventricular JJ cord-005646-xhx9pzhj 1712 11 dysfunction dysfunction NN cord-005646-xhx9pzhj 1712 12 who who WP cord-005646-xhx9pzhj 1712 13 frequently frequently RB cord-005646-xhx9pzhj 1712 14 demonstrate demonstrate VBP cord-005646-xhx9pzhj 1712 15 increased increase VBN cord-005646-xhx9pzhj 1712 16 heart heart NN cord-005646-xhx9pzhj 1712 17 rates rate NNS cord-005646-xhx9pzhj 1712 18 . . . cord-005646-xhx9pzhj 1713 1 Attempts attempt NNS cord-005646-xhx9pzhj 1713 2 to to TO cord-005646-xhx9pzhj 1713 3 maintain maintain VB cord-005646-xhx9pzhj 1713 4 low low JJ cord-005646-xhx9pzhj 1713 5 peak peak NN cord-005646-xhx9pzhj 1713 6 airway airway NN cord-005646-xhx9pzhj 1713 7 pressures pressure NNS cord-005646-xhx9pzhj 1713 8 during during IN cord-005646-xhx9pzhj 1713 9 CMV CMV NNP cord-005646-xhx9pzhj 1713 10 may may MD cord-005646-xhx9pzhj 1713 11 result result VB cord-005646-xhx9pzhj 1713 12 in in IN cord-005646-xhx9pzhj 1713 13 a a DT cord-005646-xhx9pzhj 1713 14 prolonged prolonged JJ cord-005646-xhx9pzhj 1713 15 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1713 16 time time NN cord-005646-xhx9pzhj 1713 17 that that WDT cord-005646-xhx9pzhj 1713 18 occurs occur VBZ cord-005646-xhx9pzhj 1713 19 over over IN cord-005646-xhx9pzhj 1713 20 multiple multiple JJ cord-005646-xhx9pzhj 1713 21 cardiac cardiac JJ cord-005646-xhx9pzhj 1713 22 cycles cycle NNS cord-005646-xhx9pzhj 1713 23 . . . cord-005646-xhx9pzhj 1714 1 This this DT cord-005646-xhx9pzhj 1714 2 may may MD cord-005646-xhx9pzhj 1714 3 alter alter VB cord-005646-xhx9pzhj 1714 4 LV LV NNP cord-005646-xhx9pzhj 1714 5 filling fill VBG cord-005646-xhx9pzhj 1714 6 in in RP cord-005646-xhx9pzhj 1714 7 the the DT cord-005646-xhx9pzhj 1714 8 later later JJ cord-005646-xhx9pzhj 1714 9 cardiac cardiac JJ cord-005646-xhx9pzhj 1714 10 cycles cycle NNS cord-005646-xhx9pzhj 1714 11 . . . cord-005646-xhx9pzhj 1715 1 To to TO cord-005646-xhx9pzhj 1715 2 determine determine VB cord-005646-xhx9pzhj 1715 3 the the DT cord-005646-xhx9pzhj 1715 4 effects effect NNS cord-005646-xhx9pzhj 1715 5 of of IN cord-005646-xhx9pzhj 1715 6 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1715 7 time time NN cord-005646-xhx9pzhj 1715 8 on on IN cord-005646-xhx9pzhj 1715 9 LV LV NNP cord-005646-xhx9pzhj 1715 10 diastolic diastolic JJ cord-005646-xhx9pzhj 1715 11 filling filling NN cord-005646-xhx9pzhj 1715 12 , , , cord-005646-xhx9pzhj 1715 13 10 10 CD cord-005646-xhx9pzhj 1715 14 infants infant NNS cord-005646-xhx9pzhj 1715 15 were be VBD cord-005646-xhx9pzhj 1715 16 examined examine VBN cord-005646-xhx9pzhj 1715 17 with with IN cord-005646-xhx9pzhj 1715 18 Doppler Doppler NNP cord-005646-xhx9pzhj 1715 19 echocardiography echocardiography NN cord-005646-xhx9pzhj 1715 20 less less JJR cord-005646-xhx9pzhj 1715 21 than than IN cord-005646-xhx9pzhj 1715 22 24 24 CD cord-005646-xhx9pzhj 1715 23 hrs hrs NN cord-005646-xhx9pzhj 1715 24 after after IN cord-005646-xhx9pzhj 1715 25 surgery surgery NN cord-005646-xhx9pzhj 1715 26 for for IN cord-005646-xhx9pzhj 1715 27 the the DT cord-005646-xhx9pzhj 1715 28 arterial arterial JJ cord-005646-xhx9pzhj 1715 29 switch switch NN cord-005646-xhx9pzhj 1715 30 procedtme procedtme NNP cord-005646-xhx9pzhj 1715 31 . . . cord-005646-xhx9pzhj 1716 1 Pulsed pulse VBN cord-005646-xhx9pzhj 1716 2 Doppler Doppler NNP cord-005646-xhx9pzhj 1716 3 recordings recording NNS cord-005646-xhx9pzhj 1716 4 of of IN cord-005646-xhx9pzhj 1716 5 the the DT cord-005646-xhx9pzhj 1716 6 millal millal NN cord-005646-xhx9pzhj 1716 7 valve valve NN cord-005646-xhx9pzhj 1716 8 ( ( -LRB- cord-005646-xhx9pzhj 1716 9 MV MV NNP cord-005646-xhx9pzhj 1716 10 ) ) -RRB- cord-005646-xhx9pzhj 1716 11 were be VBD cord-005646-xhx9pzhj 1716 12 obtained obtain VBN cord-005646-xhx9pzhj 1716 13 with with IN cord-005646-xhx9pzhj 1716 14 the the DT cord-005646-xhx9pzhj 1716 15 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1716 16 time time NN cord-005646-xhx9pzhj 1716 17 adjusted adjust VBN cord-005646-xhx9pzhj 1716 18 to to TO cord-005646-xhx9pzhj 1716 19 occur occur VB cord-005646-xhx9pzhj 1716 20 over over IN cord-005646-xhx9pzhj 1716 21 3 3 CD cord-005646-xhx9pzhj 1716 22 cardiac cardiac JJ cord-005646-xhx9pzhj 1716 23 cycles cycle NNS cord-005646-xhx9pzhj 1716 24 ( ( -LRB- cord-005646-xhx9pzhj 1716 25 21 21 CD cord-005646-xhx9pzhj 1716 26 sec sec NNP cord-005646-xhx9pzhj 1716 27 . . . cord-005646-xhx9pzhj 1716 28 ) ) -RRB- cord-005646-xhx9pzhj 1716 29 . . . cord-005646-xhx9pzhj 1717 1 A a DT cord-005646-xhx9pzhj 1717 2 pressure pressure NN cord-005646-xhx9pzhj 1717 3 transducer transducer NN cord-005646-xhx9pzhj 1717 4 was be VBD cord-005646-xhx9pzhj 1717 5 placed place VBN cord-005646-xhx9pzhj 1717 6 in in IN cord-005646-xhx9pzhj 1717 7 line line NN cord-005646-xhx9pzhj 1717 8 with with IN cord-005646-xhx9pzhj 1717 9 the the DT cord-005646-xhx9pzhj 1717 10 ventilator ventilator NN cord-005646-xhx9pzhj 1717 11 , , , cord-005646-xhx9pzhj 1717 12 and and CC cord-005646-xhx9pzhj 1717 13 the the DT cord-005646-xhx9pzhj 1717 14 respiratory respiratory JJ cord-005646-xhx9pzhj 1717 15 cycle cycle NN cord-005646-xhx9pzhj 1717 16 was be VBD cord-005646-xhx9pzhj 1717 17 recorded record VBN cord-005646-xhx9pzhj 1717 18 superimposed superimpose VBN cord-005646-xhx9pzhj 1717 19 on on IN cord-005646-xhx9pzhj 1717 20 the the DT cord-005646-xhx9pzhj 1717 21 Doppler doppler NN cord-005646-xhx9pzhj 1717 22 tracing tracing NN cord-005646-xhx9pzhj 1717 23 to to TO cord-005646-xhx9pzhj 1717 24 provide provide VB cord-005646-xhx9pzhj 1717 25 accurate accurate JJ cord-005646-xhx9pzhj 1717 26 determination determination NN cord-005646-xhx9pzhj 1717 27 of of IN cord-005646-xhx9pzhj 1717 28 inspiration inspiration NN cord-005646-xhx9pzhj 1717 29 and and CC cord-005646-xhx9pzhj 1717 30 expiration expiration NN cord-005646-xhx9pzhj 1717 31 . . . cord-005646-xhx9pzhj 1718 1 Doppler Doppler NNP cord-005646-xhx9pzhj 1718 2 recordings recording NNS cord-005646-xhx9pzhj 1718 3 were be VBD cord-005646-xhx9pzhj 1718 4 obtained obtain VBN cord-005646-xhx9pzhj 1718 5 from from IN cord-005646-xhx9pzhj 1718 6 the the DT cord-005646-xhx9pzhj 1718 7 apical apical JJ cord-005646-xhx9pzhj 1718 8 4-chamber 4-chamber CD cord-005646-xhx9pzhj 1718 9 view view NN cord-005646-xhx9pzhj 1718 10 and and CC cord-005646-xhx9pzhj 1718 11 the the DT cord-005646-xhx9pzhj 1718 12 following follow VBG cord-005646-xhx9pzhj 1718 13 measurements measurement NNS cord-005646-xhx9pzhj 1718 14 were be VBD cord-005646-xhx9pzhj 1718 15 made make VBN cord-005646-xhx9pzhj 1718 16 : : : cord-005646-xhx9pzhj 1718 17 peak peak NNP cord-005646-xhx9pzhj 1718 18 E E NNP cord-005646-xhx9pzhj 1718 19 and and CC cord-005646-xhx9pzhj 1718 20 peak peak VB cord-005646-xhx9pzhj 1718 21 A A NNP cord-005646-xhx9pzhj 1718 22 velocities velocity NNS cord-005646-xhx9pzhj 1718 23 , , , cord-005646-xhx9pzhj 1718 24 EIA EIA NNP cord-005646-xhx9pzhj 1718 25 ratio ratio NN cord-005646-xhx9pzhj 1718 26 , , , cord-005646-xhx9pzhj 1718 27 and and CC cord-005646-xhx9pzhj 1718 28 deceleration deceleration NN cord-005646-xhx9pzhj 1718 29 time time NN cord-005646-xhx9pzhj 1718 30 . . . cord-005646-xhx9pzhj 1719 1 Compared compare VBN cord-005646-xhx9pzhj 1719 2 to to IN cord-005646-xhx9pzhj 1719 3 the the DT cord-005646-xhx9pzhj 1719 4 expiratory expiratory JJ cord-005646-xhx9pzhj 1719 5 phase phase NN cord-005646-xhx9pzhj 1719 6 of of IN cord-005646-xhx9pzhj 1719 7 CMV CMV NNP cord-005646-xhx9pzhj 1719 8 , , , cord-005646-xhx9pzhj 1719 9 the the DT cord-005646-xhx9pzhj 1719 10 initial initial JJ cord-005646-xhx9pzhj 1719 11 beat beat NN cord-005646-xhx9pzhj 1719 12 during during IN cord-005646-xhx9pzhj 1719 13 the the DT cord-005646-xhx9pzhj 1719 14 iuspiratory iuspiratory JJ cord-005646-xhx9pzhj 1719 15 phase phase NN cord-005646-xhx9pzhj 1719 16 of of IN cord-005646-xhx9pzhj 1719 17 CMV CMV NNP cord-005646-xhx9pzhj 1719 18 resulted result VBD cord-005646-xhx9pzhj 1719 19 in in IN cord-005646-xhx9pzhj 1719 20 an an DT cord-005646-xhx9pzhj 1719 21 increase increase NN cord-005646-xhx9pzhj 1719 22 in in IN cord-005646-xhx9pzhj 1719 23 MV MV NNP cord-005646-xhx9pzhj 1719 24 peak peak NN cord-005646-xhx9pzhj 1719 25 E e NN cord-005646-xhx9pzhj 1719 26 ( ( -LRB- cord-005646-xhx9pzhj 1719 27 .53 .53 . cord-005646-xhx9pzhj 1720 1 + + CC cord-005646-xhx9pzhj 1720 2 -.06 -.06 . cord-005646-xhx9pzhj 1721 1 vs vs IN cord-005646-xhx9pzhj 1721 2 .65 .65 CD cord-005646-xhx9pzhj 1721 3 -+ -+ . cord-005646-xhx9pzhj 1722 1 .08 .08 NFP cord-005646-xhx9pzhj 1722 2 m m NNP cord-005646-xhx9pzhj 1722 3 / / SYM cord-005646-xhx9pzhj 1722 4 s s NNP cord-005646-xhx9pzhj 1722 5 , , , cord-005646-xhx9pzhj 1722 6 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1722 7 ) ) -RRB- cord-005646-xhx9pzhj 1723 1 and and CC cord-005646-xhx9pzhj 1723 2 peak peak VB cord-005646-xhx9pzhj 1723 3 A A NNP cord-005646-xhx9pzhj 1723 4 ( ( -LRB- cord-005646-xhx9pzhj 1723 5 .47 .47 CD cord-005646-xhx9pzhj 1723 6 + + CD cord-005646-xhx9pzhj 1723 7 .07 .07 . cord-005646-xhx9pzhj 1724 1 vs vs IN cord-005646-xhx9pzhj 1724 2 .63 .63 NFP cord-005646-xhx9pzhj 1725 1 -+ -+ NNP cord-005646-xhx9pzhj 1725 2 .09 .09 NFP cord-005646-xhx9pzhj 1725 3 m m NNP cord-005646-xhx9pzhj 1725 4 / / SYM cord-005646-xhx9pzhj 1725 5 s s NNP cord-005646-xhx9pzhj 1725 6 , , , cord-005646-xhx9pzhj 1725 7 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1725 8 ) ) -RRB- cord-005646-xhx9pzhj 1725 9 velocities velocity NNS cord-005646-xhx9pzhj 1725 10 with with IN cord-005646-xhx9pzhj 1725 11 no no DT cord-005646-xhx9pzhj 1725 12 change change NN cord-005646-xhx9pzhj 1725 13 in in IN cord-005646-xhx9pzhj 1725 14 MV MV NNP cord-005646-xhx9pzhj 1725 15 deceleration deceleration NN cord-005646-xhx9pzhj 1725 16 times time NNS cord-005646-xhx9pzhj 1725 17 ( ( -LRB- cord-005646-xhx9pzhj 1725 18 p<.01 p<.01 JJ cord-005646-xhx9pzhj 1725 19 ) ) -RRB- cord-005646-xhx9pzhj 1725 20 . . . cord-005646-xhx9pzhj 1726 1 Compared compare VBN cord-005646-xhx9pzhj 1726 2 to to IN cord-005646-xhx9pzhj 1726 3 the the DT cord-005646-xhx9pzhj 1726 4 initial initial JJ cord-005646-xhx9pzhj 1726 5 beat beat NN cord-005646-xhx9pzhj 1726 6 during during IN cord-005646-xhx9pzhj 1726 7 tile tile NN cord-005646-xhx9pzhj 1726 8 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1726 9 phase phase NN cord-005646-xhx9pzhj 1726 10 , , , cord-005646-xhx9pzhj 1726 11 the the DT cord-005646-xhx9pzhj 1726 12 third third JJ cord-005646-xhx9pzhj 1726 13 beat beat NN cord-005646-xhx9pzhj 1726 14 during during IN cord-005646-xhx9pzhj 1726 15 the the DT cord-005646-xhx9pzhj 1726 16 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1726 17 phase phase NN cord-005646-xhx9pzhj 1726 18 resulted result VBD cord-005646-xhx9pzhj 1726 19 in in IN cord-005646-xhx9pzhj 1726 20 decreased decrease VBN cord-005646-xhx9pzhj 1726 21 peak peak NN cord-005646-xhx9pzhj 1726 22 E e NN cord-005646-xhx9pzhj 1726 23 ( ( -LRB- cord-005646-xhx9pzhj 1726 24 .65 .65 NFP cord-005646-xhx9pzhj 1726 25 + + CC cord-005646-xhx9pzhj 1726 26 .08 .08 . cord-005646-xhx9pzhj 1727 1 vs vs IN cord-005646-xhx9pzhj 1727 2 .40 .40 NFP cord-005646-xhx9pzhj 1728 1 + + CC cord-005646-xhx9pzhj 1728 2 .05 .05 NN cord-005646-xhx9pzhj 1728 3 m m NN cord-005646-xhx9pzhj 1728 4 / / SYM cord-005646-xhx9pzhj 1728 5 s s NNP cord-005646-xhx9pzhj 1728 6 , , , cord-005646-xhx9pzhj 1728 7 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1728 8 ) ) -RRB- cord-005646-xhx9pzhj 1729 1 and and CC cord-005646-xhx9pzhj 1729 2 peak peak VB cord-005646-xhx9pzhj 1729 3 A A NNP cord-005646-xhx9pzhj 1729 4 ( ( -LRB- cord-005646-xhx9pzhj 1729 5 .63 .63 CD cord-005646-xhx9pzhj 1729 6 + + CC cord-005646-xhx9pzhj 1729 7 .09 .09 . cord-005646-xhx9pzhj 1730 1 vs vs IN cord-005646-xhx9pzhj 1730 2 .40 .40 NFP cord-005646-xhx9pzhj 1731 1 + + CC cord-005646-xhx9pzhj 1731 2 .05 .05 NN cord-005646-xhx9pzhj 1731 3 m m NN cord-005646-xhx9pzhj 1731 4 / / SYM cord-005646-xhx9pzhj 1731 5 s s NNP cord-005646-xhx9pzhj 1731 6 , , , cord-005646-xhx9pzhj 1731 7 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 1731 8 ) ) -RRB- cord-005646-xhx9pzhj 1731 9 velocities velocity NNS cord-005646-xhx9pzhj 1731 10 with with IN cord-005646-xhx9pzhj 1731 11 no no DT cord-005646-xhx9pzhj 1731 12 difference difference NN cord-005646-xhx9pzhj 1731 13 in in IN cord-005646-xhx9pzhj 1731 14 deceleration deceleration NN cord-005646-xhx9pzhj 1731 15 times time NNS cord-005646-xhx9pzhj 1731 16 . . . cord-005646-xhx9pzhj 1732 1 Thus thus RB cord-005646-xhx9pzhj 1732 2 , , , cord-005646-xhx9pzhj 1732 3 CMV CMV NNP cord-005646-xhx9pzhj 1732 4 augments augment VBZ cord-005646-xhx9pzhj 1732 5 LV LV NNP cord-005646-xhx9pzhj 1732 6 filling fill VBG cord-005646-xhx9pzhj 1732 7 during during IN cord-005646-xhx9pzhj 1732 8 the the DT cord-005646-xhx9pzhj 1732 9 initial initial JJ cord-005646-xhx9pzhj 1732 10 phase phase NN cord-005646-xhx9pzhj 1732 11 of of IN cord-005646-xhx9pzhj 1732 12 inspiration inspiration NN cord-005646-xhx9pzhj 1732 13 . . . cord-005646-xhx9pzhj 1733 1 However however RB cord-005646-xhx9pzhj 1733 2 , , , cord-005646-xhx9pzhj 1733 3 as as IN cord-005646-xhx9pzhj 1733 4 the the DT cord-005646-xhx9pzhj 1733 5 increase increase NN cord-005646-xhx9pzhj 1733 6 in in IN cord-005646-xhx9pzhj 1733 7 airway airway NN cord-005646-xhx9pzhj 1733 8 pressure pressure NN cord-005646-xhx9pzhj 1733 9 is be VBZ cord-005646-xhx9pzhj 1733 10 distributed distribute VBN cord-005646-xhx9pzhj 1733 11 over over IN cord-005646-xhx9pzhj 1733 12 multiple multiple JJ cord-005646-xhx9pzhj 1733 13 cardiac cardiac JJ cord-005646-xhx9pzhj 1733 14 cycles cycle NNS cord-005646-xhx9pzhj 1733 15 , , , cord-005646-xhx9pzhj 1733 16 LV LV NNP cord-005646-xhx9pzhj 1733 17 filling filling NN cord-005646-xhx9pzhj 1733 18 falls fall VBZ cord-005646-xhx9pzhj 1733 19 below below IN cord-005646-xhx9pzhj 1733 20 baseline baseline JJ cord-005646-xhx9pzhj 1733 21 levels level NNS cord-005646-xhx9pzhj 1733 22 . . . cord-005646-xhx9pzhj 1734 1 These these DT cord-005646-xhx9pzhj 1734 2 observations observation NNS cord-005646-xhx9pzhj 1734 3 indicate indicate VBP cord-005646-xhx9pzhj 1734 4 that that IN cord-005646-xhx9pzhj 1734 5 while while IN cord-005646-xhx9pzhj 1734 6 thoracic thoracic JJ cord-005646-xhx9pzhj 1734 7 augmentation augmentation NN cord-005646-xhx9pzhj 1734 8 may may MD cord-005646-xhx9pzhj 1734 9 be be VB cord-005646-xhx9pzhj 1734 10 beneficial beneficial JJ cord-005646-xhx9pzhj 1734 11 , , , cord-005646-xhx9pzhj 1734 12 to to TO cord-005646-xhx9pzhj 1734 13 optimize optimize VB cord-005646-xhx9pzhj 1734 14 LV LV NNP cord-005646-xhx9pzhj 1734 15 filling fill VBG cord-005646-xhx9pzhj 1734 16 the the DT cord-005646-xhx9pzhj 1734 17 inspiratory inspiratory JJ cord-005646-xhx9pzhj 1734 18 time time NN cord-005646-xhx9pzhj 1734 19 of of IN cord-005646-xhx9pzhj 1734 20 CMV CMV NNP cord-005646-xhx9pzhj 1734 21 must must MD cord-005646-xhx9pzhj 1734 22 be be VB cord-005646-xhx9pzhj 1734 23 < < NNP cord-005646-xhx9pzhj 1734 24 3 3 CD cord-005646-xhx9pzhj 1734 25 cardiac cardiac JJ cord-005646-xhx9pzhj 1734 26 cycles cycle NNS cord-005646-xhx9pzhj 1734 27 . . . cord-005646-xhx9pzhj 1735 1 Energy energy NN cord-005646-xhx9pzhj 1735 2 expenditure expenditure NN cord-005646-xhx9pzhj 1735 3 in in IN cord-005646-xhx9pzhj 1735 4 pediatric pediatric JJ cord-005646-xhx9pzhj 1735 5 orthotopic orthotopic NNP cord-005646-xhx9pzhj 1735 6 liver liver NNP cord-005646-xhx9pzhj 1735 7 tranaplantat tranaplantat NNP cord-005646-xhx9pzhj 1735 8 ~ ~ NFP cord-005646-xhx9pzhj 1735 9 on on IN cord-005646-xhx9pzhj 1735 10 , , , cord-005646-xhx9pzhj 1735 11 _SP cord-005646-xhx9pzhj 1736 1 To to TO cord-005646-xhx9pzhj 1736 2 determine determine VB cord-005646-xhx9pzhj 1736 3 the the DT cord-005646-xhx9pzhj 1736 4 actual actual JJ cord-005646-xhx9pzhj 1736 5 calorie calorie NN cord-005646-xhx9pzhj 1736 6 requirements requirement NNS cord-005646-xhx9pzhj 1736 7 of of IN cord-005646-xhx9pzhj 1736 8 critically critically RB cord-005646-xhx9pzhj 1736 9 ill ill JJ cord-005646-xhx9pzhj 1736 10 children child NNS cord-005646-xhx9pzhj 1736 11 and and CC cord-005646-xhx9pzhj 1736 12 evniuate evniuate VB cord-005646-xhx9pzhj 1736 13 the the DT cord-005646-xhx9pzhj 1736 14 correlations correlation NNS cord-005646-xhx9pzhj 1736 15 between between IN cord-005646-xhx9pzhj 1736 16 measured measure VBN cord-005646-xhx9pzhj 1736 17 , , , cord-005646-xhx9pzhj 1736 18 stress stress NN cord-005646-xhx9pzhj 1736 19 - - HYPH cord-005646-xhx9pzhj 1736 20 p p NN cord-005646-xhx9pzhj 1736 21 ~ ~ NFP cord-005646-xhx9pzhj 1736 22 lictod lictod NNP cord-005646-xhx9pzhj 1736 23 and and CC cord-005646-xhx9pzhj 1736 24 repleted repleted JJ cord-005646-xhx9pzhj 1736 25 energy energy NNP cord-005646-xhx9pzhj 1736 26 exponditttm exponditttm NNS cord-005646-xhx9pzhj 1736 27 and and CC cord-005646-xhx9pzhj 1736 28 the the DT cord-005646-xhx9pzhj 1736 29 severity severity NN cord-005646-xhx9pzhj 1736 30 of of IN cord-005646-xhx9pzhj 1736 31 illness illness NN cord-005646-xhx9pzhj 1736 32 . . . cord-005646-xhx9pzhj 1737 1 Des Des NNP cord-005646-xhx9pzhj 1737 2 / / SYM cord-005646-xhx9pzhj 1737 3 gn gn NNP cord-005646-xhx9pzhj 1737 4 : : : cord-005646-xhx9pzhj 1737 5 A a DT cord-005646-xhx9pzhj 1737 6 prospective prospective JJ cord-005646-xhx9pzhj 1737 7 , , , cord-005646-xhx9pzhj 1737 8 dinlcal dinlcal JJ cord-005646-xhx9pzhj 1737 9 study study NN cord-005646-xhx9pzhj 1737 10 . . . cord-005646-xhx9pzhj 1738 1 Se Se NNP cord-005646-xhx9pzhj 1738 2 ~ ~ NFP cord-005646-xhx9pzhj 1738 3 ng ng NN cord-005646-xhx9pzhj 1738 4 : : : cord-005646-xhx9pzhj 1738 5 Tertiary tertiary JJ cord-005646-xhx9pzhj 1738 6 care care NN cord-005646-xhx9pzhj 1738 7 pediatric pediatric JJ cord-005646-xhx9pzhj 1738 8 ICU ICU NNP cord-005646-xhx9pzhj 1738 9 in in IN cord-005646-xhx9pzhj 1738 10 a a DT cord-005646-xhx9pzhj 1738 11 university university NN cord-005646-xhx9pzhj 1738 12 hospital hospital NN cord-005646-xhx9pzhj 1738 13 . . . cord-005646-xhx9pzhj 1739 1 Patients patient NNS cord-005646-xhx9pzhj 1739 2 : : : cord-005646-xhx9pzhj 1740 1 Ten ten CD cord-005646-xhx9pzhj 1740 2 patients patient NNS cord-005646-xhx9pzhj 1740 3 aged age VBN cord-005646-xhx9pzhj 1740 4 6 6 CD cord-005646-xhx9pzhj 1740 5 to to IN cord-005646-xhx9pzhj 1740 6 210 210 CD cord-005646-xhx9pzhj 1740 7 months month NNS cord-005646-xhx9pzhj 1740 8 with with IN cord-005646-xhx9pzhj 1740 9 disorders disorder NNS cord-005646-xhx9pzhj 1740 10 prompting prompt VBG cord-005646-xhx9pzhj 1740 11 PICU PICU NNP cord-005646-xhx9pzhj 1740 12 admission admission NN cord-005646-xhx9pzhj 1740 13 , , , cord-005646-xhx9pzhj 1740 14 including include VBG cord-005646-xhx9pzhj 1740 15 sepsis sepsis NN cord-005646-xhx9pzhj 1740 16 , , , cord-005646-xhx9pzhj 1740 17 respiratory respiratory JJ cord-005646-xhx9pzhj 1740 18 failure failure NN cord-005646-xhx9pzhj 1740 19 , , , cord-005646-xhx9pzhj 1740 20 solid solid JJ cord-005646-xhx9pzhj 1740 21 organ organ NN cord-005646-xhx9pzhj 1740 22 transplantation transplantation NN cord-005646-xhx9pzhj 1740 23 , , , cord-005646-xhx9pzhj 1740 24 and and CC cord-005646-xhx9pzhj 1740 25 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 1740 26 surgery surgery NN cord-005646-xhx9pzhj 1740 27 . . . cord-005646-xhx9pzhj 1741 1 Inta Inta NNP cord-005646-xhx9pzhj 1741 2 ~ ~ CD cord-005646-xhx9pzhj 1741 3 entions ention NNS cord-005646-xhx9pzhj 1741 4 : : : cord-005646-xhx9pzhj 1741 5 All all DT cord-005646-xhx9pzhj 1741 6 patients patient NNS cord-005646-xhx9pzhj 1741 7 were be VBD cord-005646-xhx9pzhj 1741 8 studied study VBN cord-005646-xhx9pzhj 1741 9 within within IN cord-005646-xhx9pzhj 1741 10 24 24 CD cord-005646-xhx9pzhj 1741 11 hrs hrs NN cord-005646-xhx9pzhj 1741 12 of of IN cord-005646-xhx9pzhj 1741 13 major major JJ cord-005646-xhx9pzhj 1741 14 surgery surgery NN cord-005646-xhx9pzhj 1741 15 or or CC cord-005646-xhx9pzhj 1741 16 transplantation transplantation NN cord-005646-xhx9pzhj 1741 17 , , , cord-005646-xhx9pzhj 1741 18 or or CC cord-005646-xhx9pzhj 1741 19 following follow VBG cord-005646-xhx9pzhj 1741 20 acute acute JJ cord-005646-xhx9pzhj 1741 21 illness illness NN cord-005646-xhx9pzhj 1741 22 . . . cord-005646-xhx9pzhj 1742 1 All all DT cord-005646-xhx9pzhj 1742 2 patienls patienls NN cord-005646-xhx9pzhj 1742 3 were be VBD cord-005646-xhx9pzhj 1742 4 severely severely RB cord-005646-xhx9pzhj 1742 5 stressed stress VBN cord-005646-xhx9pzhj 1742 6 clinically clinically RB cord-005646-xhx9pzhj 1742 7 and and CC cord-005646-xhx9pzhj 1742 8 all all DT cord-005646-xhx9pzhj 1742 9 but but CC cord-005646-xhx9pzhj 1742 10 two two CD cord-005646-xhx9pzhj 1742 11 were be VBD cord-005646-xhx9pzhj 1742 12 intubated intubate VBN cord-005646-xhx9pzhj 1742 13 by by IN cord-005646-xhx9pzhj 1742 14 cuffed cuffed JJ cord-005646-xhx9pzhj 1742 15 tubes tube NNS cord-005646-xhx9pzhj 1742 16 , , , cord-005646-xhx9pzhj 1742 17 In in IN cord-005646-xhx9pzhj 1742 18 three three CD cord-005646-xhx9pzhj 1742 19 of of IN cord-005646-xhx9pzhj 1742 20 them -PRON- PRP cord-005646-xhx9pzhj 1742 21 , , , cord-005646-xhx9pzhj 1742 22 still still RB cord-005646-xhx9pzhj 1742 23 in in IN cord-005646-xhx9pzhj 1742 24 a a DT cord-005646-xhx9pzhj 1742 25 stress stress NN cord-005646-xhx9pzhj 1742 26 state state NN cord-005646-xhx9pzhj 1742 27 , , , cord-005646-xhx9pzhj 1742 28 the the DT cord-005646-xhx9pzhj 1742 29 study study NN cord-005646-xhx9pzhj 1742 30 repeated repeat VBD cord-005646-xhx9pzhj 1742 31 on on IN cord-005646-xhx9pzhj 1742 32 the the DT cord-005646-xhx9pzhj 1742 33 third third JJ cord-005646-xhx9pzhj 1742 34 day day NN cord-005646-xhx9pzhj 1742 35 of of IN cord-005646-xhx9pzhj 1742 36 the the DT cord-005646-xhx9pzhj 1742 37 disease disease NN cord-005646-xhx9pzhj 1742 38 , , , cord-005646-xhx9pzhj 1742 39 Energy Energy NNP cord-005646-xhx9pzhj 1742 40 expenditure expenditure NN cord-005646-xhx9pzhj 1742 41 mensurements mensurement NNS cord-005646-xhx9pzhj 1742 42 ( ( -LRB- cord-005646-xhx9pzhj 1742 43 MEE MEE NNP cord-005646-xhx9pzhj 1742 44 ) ) -RRB- cord-005646-xhx9pzhj 1742 45 , , , cord-005646-xhx9pzhj 1742 46 as as RB cord-005646-xhx9pzhj 1742 47 well well RB cord-005646-xhx9pzhj 1742 48 as as IN cord-005646-xhx9pzhj 1742 49 illness illness NN cord-005646-xhx9pzhj 1742 50 seventy seventy CD cord-005646-xhx9pzhj 1742 51 scoring scoring NN cord-005646-xhx9pzhj 1742 52 systems system NNS cord-005646-xhx9pzhj 1742 53 , , , cord-005646-xhx9pzhj 1742 54 mtfltisystern mtfltisystern NNP cord-005646-xhx9pzhj 1742 55 organ organ NN cord-005646-xhx9pzhj 1742 56 failure failure NN cord-005646-xhx9pzhj 1742 57 scores score NNS cord-005646-xhx9pzhj 1742 58 and and CC cord-005646-xhx9pzhj 1742 59 various various JJ cord-005646-xhx9pzhj 1742 60 anthropemetric anthropemetric JJ cord-005646-xhx9pzhj 1742 61 and and CC cord-005646-xhx9pzhj 1742 62 clinical clinical JJ cord-005646-xhx9pzhj 1742 63 indices index NNS cord-005646-xhx9pzhj 1742 64 of of IN cord-005646-xhx9pzhj 1742 65 nutritional nutritional JJ cord-005646-xhx9pzhj 1742 66 status status NN cord-005646-xhx9pzhj 1742 67 , , , cord-005646-xhx9pzhj 1742 68 the the DT cord-005646-xhx9pzhj 1742 69 stress stress NN cord-005646-xhx9pzhj 1742 70 - - HYPH cord-005646-xhx9pzhj 1742 71 predicted predict VBN cord-005646-xhx9pzhj 1742 72 energy energy NN cord-005646-xhx9pzhj 1742 73 expenditure expenditure NN cord-005646-xhx9pzhj 1742 74 ( ( -LRB- cord-005646-xhx9pzhj 1742 75 S S NNP cord-005646-xhx9pzhj 1742 76 - - HYPH cord-005646-xhx9pzhj 1742 77 PEE PEE NNP cord-005646-xhx9pzhj 1742 78 ) ) -RRB- cord-005646-xhx9pzhj 1742 79 , , , cord-005646-xhx9pzhj 1742 80 the the DT cord-005646-xhx9pzhj 1742 81 basal basal NN cord-005646-xhx9pzhj 1742 82 metabufie metabufie NN cord-005646-xhx9pzhj 1742 83 rote rote NN cord-005646-xhx9pzhj 1742 84 ( ( -LRB- cord-005646-xhx9pzhj 1742 85 PBMR PBMR NNP cord-005646-xhx9pzhj 1742 86 ) ) -RRB- cord-005646-xhx9pzhj 1742 87 , , , cord-005646-xhx9pzhj 1742 88 the the DT cord-005646-xhx9pzhj 1742 89 repleted replete VBN cord-005646-xhx9pzhj 1742 90 energy energy NN cord-005646-xhx9pzhj 1742 91 ( ( -LRB- cord-005646-xhx9pzhj 1742 92 RE RE NNP cord-005646-xhx9pzhj 1742 93 ) ) -RRB- cord-005646-xhx9pzhj 1742 94 and and CC cord-005646-xhx9pzhj 1742 95 the the DT cord-005646-xhx9pzhj 1742 96 recommended recommend VBN cord-005646-xhx9pzhj 1742 97 dietary dietary JJ cord-005646-xhx9pzhj 1742 98 allowances allowance NNS cord-005646-xhx9pzhj 1742 99 ( ( -LRB- cord-005646-xhx9pzhj 1742 100 RDA RDA NNP cord-005646-xhx9pzhj 1742 101 ) ) -RRB- cord-005646-xhx9pzhj 1742 102 were be VBD cord-005646-xhx9pzhj 1742 103 measured measure VBN cord-005646-xhx9pzhj 1742 104 or or CC cord-005646-xhx9pzhj 1742 105 calculated calculate VBN cord-005646-xhx9pzhj 1742 106 in in IN cord-005646-xhx9pzhj 1742 107 each each DT cord-005646-xhx9pzhj 1742 108 patient patient NN cord-005646-xhx9pzhj 1742 109 . . . cord-005646-xhx9pzhj 1743 1 Multiple multiple JJ cord-005646-xhx9pzhj 1743 2 regression regression NN cord-005646-xhx9pzhj 1743 3 analysis analysis NN cord-005646-xhx9pzhj 1743 4 was be VBD cord-005646-xhx9pzhj 1743 5 used use VBN cord-005646-xhx9pzhj 1743 6 to to TO cord-005646-xhx9pzhj 1743 7 analyze analyze VB cord-005646-xhx9pzhj 1743 8 the the DT cord-005646-xhx9pzhj 1743 9 data datum NNS cord-005646-xhx9pzhj 1743 10 . . . cord-005646-xhx9pzhj 1744 1 Measurements measurement NNS cord-005646-xhx9pzhj 1744 2 and and CC cord-005646-xhx9pzhj 1744 3 Main main JJ cord-005646-xhx9pzhj 1744 4 Results result NNS cord-005646-xhx9pzhj 1744 5 : : : cord-005646-xhx9pzhj 1744 6 Although although IN cord-005646-xhx9pzhj 1744 7 the the DT cord-005646-xhx9pzhj 1744 8 mean mean JJ cord-005646-xhx9pzhj 1744 9 MEE MEE NNP cord-005646-xhx9pzhj 1744 10 was be VBD cord-005646-xhx9pzhj 1744 11 significantly significantly RB cord-005646-xhx9pzhj 1744 12 lower low JJR cord-005646-xhx9pzhj 1744 13 than than IN cord-005646-xhx9pzhj 1744 14 the the DT cord-005646-xhx9pzhj 1744 15 mean mean NN cord-005646-xhx9pzhj 1744 16 S S NNP cord-005646-xhx9pzhj 1744 17 - - HYPH cord-005646-xhx9pzhj 1744 18 PEE PEE NNP cord-005646-xhx9pzhj 1744 19 ( ( -LRB- cord-005646-xhx9pzhj 1744 20 37.6 37.6 CD cord-005646-xhx9pzhj 1744 21 + + SYM cord-005646-xhx9pzhj 1744 22 11 11 CD cord-005646-xhx9pzhj 1744 23 kcal kcal NNP cord-005646-xhx9pzhj 1744 24 / / SYM cord-005646-xhx9pzhj 1744 25 kg kg NNP cord-005646-xhx9pzhj 1744 26 / / SYM cord-005646-xhx9pzhj 1744 27 day day NN cord-005646-xhx9pzhj 1744 28 vs. vs. IN cord-005646-xhx9pzhj 1744 29 50.35:16 50.35:16 CD cord-005646-xhx9pzhj 1744 30 kcal kcal NNP cord-005646-xhx9pzhj 1744 31 / / SYM cord-005646-xhx9pzhj 1744 32 kg kg NNP cord-005646-xhx9pzhj 1744 33 / / SYM cord-005646-xhx9pzhj 1744 34 day day NN cord-005646-xhx9pzhj 1744 35 , , , cord-005646-xhx9pzhj 1744 36 p<.002 p<.002 NNP cord-005646-xhx9pzhj 1744 37 ) ) -RRB- cord-005646-xhx9pzhj 1744 38 , , , cord-005646-xhx9pzhj 1744 39 it -PRON- PRP cord-005646-xhx9pzhj 1744 40 did do VBD cord-005646-xhx9pzhj 1744 41 not not RB cord-005646-xhx9pzhj 1744 42 differ differ VB cord-005646-xhx9pzhj 1744 43 significantly significantly RB cord-005646-xhx9pzhj 1744 44 from from IN cord-005646-xhx9pzhj 1744 45 the the DT cord-005646-xhx9pzhj 1744 46 PBMR PBMR NNP cord-005646-xhx9pzhj 1744 47 ( ( -LRB- cord-005646-xhx9pzhj 1744 48 mean mean VB cord-005646-xhx9pzhj 1744 49 difference difference NN cord-005646-xhx9pzhj 1744 50 -2.62 -2.62 CD cord-005646-xhx9pzhj 1745 1 kcal kcal NNP cord-005646-xhx9pzhj 1745 2 / / SYM cord-005646-xhx9pzhj 1745 3 kg kg NNP cord-005646-xhx9pzhj 1745 4 / / SYM cord-005646-xhx9pzhj 1745 5 day day NN cord-005646-xhx9pzhj 1745 6 , , , cord-005646-xhx9pzhj 1745 7 range range NN cord-005646-xhx9pzhj 1746 1 -10.07 -10.07 NNS cord-005646-xhx9pzhj 1746 2 to to IN cord-005646-xhx9pzhj 1746 3 +9.06 +9.06 NNP cord-005646-xhx9pzhj 1746 4 kcal kcal NNP cord-005646-xhx9pzhj 1746 5 / / SYM cord-005646-xhx9pzhj 1746 6 kg kg NNP cord-005646-xhx9pzhj 1746 7 / / SYM cord-005646-xhx9pzhj 1746 8 day day NN cord-005646-xhx9pzhj 1746 9 ) ) -RRB- cord-005646-xhx9pzhj 1746 10 . . . cord-005646-xhx9pzhj 1747 1 The the DT cord-005646-xhx9pzhj 1747 2 S S NNP cord-005646-xhx9pzhj 1747 3 - - HYPH cord-005646-xhx9pzhj 1747 4 PEE PEE NNP cord-005646-xhx9pzhj 1747 5 / / SYM cord-005646-xhx9pzhj 1747 6 MEE MEE NNP cord-005646-xhx9pzhj 1747 7 ratio ratio NN cord-005646-xhx9pzhj 1747 8 ranged range VBD cord-005646-xhx9pzhj 1747 9 from from IN cord-005646-xhx9pzhj 1747 10 1.04 1.04 CD cord-005646-xhx9pzhj 1747 11 to to IN cord-005646-xhx9pzhj 1747 12 2.07 2.07 CD cord-005646-xhx9pzhj 1747 13 , , , cord-005646-xhx9pzhj 1747 14 while while IN cord-005646-xhx9pzhj 1747 15 the the DT cord-005646-xhx9pzhj 1747 16 RE RE NNP cord-005646-xhx9pzhj 1747 17 / / SYM cord-005646-xhx9pzhj 1747 18 RDA RDA NNP cord-005646-xhx9pzhj 1747 19 ratio ratio NN cord-005646-xhx9pzhj 1747 20 ( ( -LRB- cord-005646-xhx9pzhj 1747 21 21.25:4 21.25:4 CD cord-005646-xhx9pzhj 1747 22 kcal kcal NNP cord-005646-xhx9pzhj 1747 23 / / SYM cord-005646-xhx9pzhj 1747 24 kg kg NNP cord-005646-xhx9pzhj 1747 25 / / SYM cord-005646-xhx9pzhj 1747 26 day)/(75.85:7 day)/(75.85:7 NNS cord-005646-xhx9pzhj 1747 27 kcal kcal NNP cord-005646-xhx9pzhj 1747 28 / / SYM cord-005646-xhx9pzhj 1747 29 kg kg NNP cord-005646-xhx9pzhj 1747 30 / / SYM cord-005646-xhx9pzhj 1747 31 dny dny NNP cord-005646-xhx9pzhj 1747 32 ) ) -RRB- cord-005646-xhx9pzhj 1747 33 ranged range VBD cord-005646-xhx9pzhj 1747 34 from from IN cord-005646-xhx9pzhj 1747 35 only only RB cord-005646-xhx9pzhj 1747 36 .1 .1 CD cord-005646-xhx9pzhj 1747 37 to to IN cord-005646-xhx9pzhj 1747 38 .5 .5 CD cord-005646-xhx9pzhj 1747 39 . . . cord-005646-xhx9pzhj 1748 1 The the DT cord-005646-xhx9pzhj 1748 2 PRISM PRISM NNP cord-005646-xhx9pzhj 1748 3 / / SYM cord-005646-xhx9pzhj 1748 4 TISS TISS NNP cord-005646-xhx9pzhj 1748 5 ratio ratio NN cord-005646-xhx9pzhj 1748 6 was be VBD cord-005646-xhx9pzhj 1748 7 not not RB cord-005646-xhx9pzhj 1748 8 correlated correlate VBN cord-005646-xhx9pzhj 1748 9 better well RBR cord-005646-xhx9pzhj 1748 10 with with IN cord-005646-xhx9pzhj 1748 11 MEE MEE NNP cord-005646-xhx9pzhj 1748 12 than than IN cord-005646-xhx9pzhj 1748 13 the the DT cord-005646-xhx9pzhj 1748 14 diagnostic diagnostic JJ cord-005646-xhx9pzhj 1748 15 category category NN cord-005646-xhx9pzhj 1748 16 ( ( -LRB- cord-005646-xhx9pzhj 1748 17 r~=.36 r~=.36 NN cord-005646-xhx9pzhj 1748 18 vs vs RB cord-005646-xhx9pzhj 1748 19 .. .. NFP cord-005646-xhx9pzhj 1748 20 38 38 CD cord-005646-xhx9pzhj 1748 21 , , , cord-005646-xhx9pzhj 1748 22 respectively respectively RB cord-005646-xhx9pzhj 1748 23 ) ) -RRB- cord-005646-xhx9pzhj 1748 24 . . . cord-005646-xhx9pzhj 1749 1 The the DT cord-005646-xhx9pzhj 1749 2 RE re NN cord-005646-xhx9pzhj 1749 3 was be VBD cord-005646-xhx9pzhj 1749 4 positively positively RB cord-005646-xhx9pzhj 1749 5 correlated correlate VBN cord-005646-xhx9pzhj 1749 6 withthe withthe DT cord-005646-xhx9pzhj 1749 7 MEE MEE NNP cord-005646-xhx9pzhj 1749 8 ( ( -LRB- cord-005646-xhx9pzhj 1749 9 rZ=.65 rz=.65 XX cord-005646-xhx9pzhj 1749 10 , , , cord-005646-xhx9pzhj 1749 11 I)=.07 i)=.07 NN cord-005646-xhx9pzhj 1749 12 ) ) -RRB- cord-005646-xhx9pzhj 1749 13 while while IN cord-005646-xhx9pzhj 1749 14 negative negative JJ cord-005646-xhx9pzhj 1749 15 oarrelatian oarrelatian NNP cord-005646-xhx9pzhj 1749 16 has have VBZ cord-005646-xhx9pzhj 1749 17 been be VBN cord-005646-xhx9pzhj 1749 18 found find VBN cord-005646-xhx9pzhj 1749 19 between between IN cord-005646-xhx9pzhj 1749 20 MEE MEE NNP cord-005646-xhx9pzhj 1749 21 and and CC cord-005646-xhx9pzhj 1749 22 age age NN cord-005646-xhx9pzhj 1749 23 , , , cord-005646-xhx9pzhj 1749 24 mid mid JJ cord-005646-xhx9pzhj 1749 25 - - JJ cord-005646-xhx9pzhj 1749 26 arm arm NN cord-005646-xhx9pzhj 1749 27 circumference circumference NN cord-005646-xhx9pzhj 1749 28 , , , cord-005646-xhx9pzhj 1749 29 triceps tricep NNS cord-005646-xhx9pzhj 1749 30 skinfotd skinfotd NN cord-005646-xhx9pzhj 1749 31 and and CC cord-005646-xhx9pzhj 1749 32 the the DT cord-005646-xhx9pzhj 1749 33 use use NN cord-005646-xhx9pzhj 1749 34 of of IN cord-005646-xhx9pzhj 1749 35 vaseactive vaseactive JJ cord-005646-xhx9pzhj 1749 36 agents agent NNS cord-005646-xhx9pzhj 1749 37 ( ( -LRB- cord-005646-xhx9pzhj 1749 38 r~.81 r~.81 UH cord-005646-xhx9pzhj 1749 39 , , , cord-005646-xhx9pzhj 1749 40 -88 -88 NN cord-005646-xhx9pzhj 1749 41 , , , cord-005646-xhx9pzhj 1749 42 -.67 -.67 NN cord-005646-xhx9pzhj 1749 43 , , , cord-005646-xhx9pzhj 1749 44 p<.005 p<.005 NN cord-005646-xhx9pzhj 1749 45 and and CC cord-005646-xhx9pzhj 1749 46 -.71 -.71 NN cord-005646-xhx9pzhj 1750 1 resp resp NNP cord-005646-xhx9pzhj 1750 2 ~ ~ NNP cord-005646-xhx9pzhj 1750 3 lively lively JJ cord-005646-xhx9pzhj 1750 4 ) ) -RRB- cord-005646-xhx9pzhj 1750 5 . . . cord-005646-xhx9pzhj 1751 1 Concl.m~ Concl.m~ NNP cord-005646-xhx9pzhj 1751 2 : : : cord-005646-xhx9pzhj 1751 3 If if IN cord-005646-xhx9pzhj 1751 4 S s NN cord-005646-xhx9pzhj 1751 5 - - HYPH cord-005646-xhx9pzhj 1751 6 PEE PEE NNP cord-005646-xhx9pzhj 1751 7 is be VBZ cord-005646-xhx9pzhj 1751 8 used use VBN cord-005646-xhx9pzhj 1751 9 for for IN cord-005646-xhx9pzhj 1751 10 caloric caloric JJ cord-005646-xhx9pzhj 1751 11 repletion repletion NN cord-005646-xhx9pzhj 1751 12 in in IN cord-005646-xhx9pzhj 1751 13 the the DT cord-005646-xhx9pzhj 1751 14 stressed stress VBN cord-005646-xhx9pzhj 1751 15 oritic oritic JJ cord-005646-xhx9pzhj 1751 16 ~ ~ NFP cord-005646-xhx9pzhj 1751 17 ly ly XX cord-005646-xhx9pzhj 1751 18 fll fll NNP cord-005646-xhx9pzhj 1751 19 el el NNP cord-005646-xhx9pzhj 1752 1 ~d ~d NFP cord-005646-xhx9pzhj 1752 2 , , , cord-005646-xhx9pzhj 1752 3 these these DT cord-005646-xhx9pzhj 1752 4 patients patient NNS cord-005646-xhx9pzhj 1752 5 will will MD cord-005646-xhx9pzhj 1752 6 be be VB cord-005646-xhx9pzhj 1752 7 substantially substantially RB cord-005646-xhx9pzhj 1752 8 overfed overfed JJ cord-005646-xhx9pzhj 1752 9 by by IN cord-005646-xhx9pzhj 1752 10 as as RB cord-005646-xhx9pzhj 1752 11 much much JJ cord-005646-xhx9pzhj 1752 12 as as IN cord-005646-xhx9pzhj 1752 13 100 100 CD cord-005646-xhx9pzhj 1752 14 % % NN cord-005646-xhx9pzhj 1752 15 . . . cord-005646-xhx9pzhj 1753 1 Although although IN cord-005646-xhx9pzhj 1753 2 PBMR PBMR NNP cord-005646-xhx9pzhj 1753 3 appears appear VBZ cord-005646-xhx9pzhj 1753 4 to to TO cord-005646-xhx9pzhj 1753 5 approximate approximate VB cord-005646-xhx9pzhj 1753 6 the the DT cord-005646-xhx9pzhj 1753 7 MEE MEE NNP cord-005646-xhx9pzhj 1753 8 by by IN cord-005646-xhx9pzhj 1753 9 ±10 ±10 NNP cord-005646-xhx9pzhj 1753 10 % % NN cord-005646-xhx9pzhj 1753 11 , , , cord-005646-xhx9pzhj 1753 12 other other JJ cord-005646-xhx9pzhj 1753 13 clinical clinical JJ cord-005646-xhx9pzhj 1753 14 and and CC cord-005646-xhx9pzhj 1753 15 nutritional nutritional JJ cord-005646-xhx9pzhj 1753 16 indices index NNS cord-005646-xhx9pzhj 1753 17 should should MD cord-005646-xhx9pzhj 1753 18 also also RB cord-005646-xhx9pzhj 1753 19 be be VB cord-005646-xhx9pzhj 1753 20 ennsidered ennsidere VBN cord-005646-xhx9pzhj 1753 21 . . . cord-005646-xhx9pzhj 1754 1 Objective objective NN cord-005646-xhx9pzhj 1754 2 : : : cord-005646-xhx9pzhj 1755 1 To to TO cord-005646-xhx9pzhj 1755 2 deter deter VB cord-005646-xhx9pzhj 1755 3 .mine .mine NFP cord-005646-xhx9pzhj 1755 4 .. .. . cord-005646-xhx9pzhj 1756 1 t.he t.he NNP cord-005646-xhx9pzhj 1757 1 metabpli.c metabpli.c NNP cord-005646-xhx9pzhj 1758 1 and.nutritional and.nutritional NNP cord-005646-xhx9pzhj 1758 2 state state NN cord-005646-xhx9pzhj 1758 3 of of IN cord-005646-xhx9pzhj 1758 4 mechanically mechanically RB cord-005646-xhx9pzhj 1758 5 ventilated ventilate VBN cord-005646-xhx9pzhj 1758 6 intants intant NNS cord-005646-xhx9pzhj 1758 7 and and CC cord-005646-xhx9pzhj 1758 8 children child NNS cord-005646-xhx9pzhj 1758 9 m m NNP cord-005646-xhx9pzhj 1758 10 relatmn relatmn NNP cord-005646-xhx9pzhj 1758 11 wlm wlm NNP cord-005646-xhx9pzhj 1758 12 severity severity NN cord-005646-xhx9pzhj 1758 13 or or CC cord-005646-xhx9pzhj 1758 14 msease msease NN cord-005646-xhx9pzhj 1758 15 . . . cord-005646-xhx9pzhj 1759 1 Patients patient NNS cord-005646-xhx9pzhj 1759 2 and and CC cord-005646-xhx9pzhj 1759 3 methods method NNS cord-005646-xhx9pzhj 1759 4 : : : cord-005646-xhx9pzhj 1759 5 37 37 CD cord-005646-xhx9pzhj 1759 6 Mechanically mechanically RB cord-005646-xhx9pzhj 1759 7 ventilated ventilate VBD cord-005646-xhx9pzhj 1759 8 infants infant NNS cord-005646-xhx9pzhj 1759 9 and and CC cord-005646-xhx9pzhj 1759 10 children child NNS cord-005646-xhx9pzhj 1759 11 , , , cord-005646-xhx9pzhj 1759 12 median median NN cord-005646-xhx9pzhj 1759 13 age age NN cord-005646-xhx9pzhj 1759 14 7 7 CD cord-005646-xhx9pzhj 1759 15 months month NNS cord-005646-xhx9pzhj 1759 16 ( ( -LRB- cord-005646-xhx9pzhj 1759 17 range range VBP cord-005646-xhx9pzhj 1759 18 3 3 CD cord-005646-xhx9pzhj 1759 19 days day NNS cord-005646-xhx9pzhj 1759 20 to to IN cord-005646-xhx9pzhj 1759 21 13years 13years CD cord-005646-xhx9pzhj 1759 22 ) ) -RRB- cord-005646-xhx9pzhj 1759 23 , , , cord-005646-xhx9pzhj 1759 24 were be VBD cord-005646-xhx9pzhj 1759 25 studied study VBN cord-005646-xhx9pzhj 1759 26 . . . cord-005646-xhx9pzhj 1760 1 Severity severity NN cord-005646-xhx9pzhj 1760 2 of of IN cord-005646-xhx9pzhj 1760 3 illness illness NN cord-005646-xhx9pzhj 1760 4 was be VBD cord-005646-xhx9pzhj 1760 5 assessed assess VBN cord-005646-xhx9pzhj 1760 6 using use VBG cord-005646-xhx9pzhj 1760 7 PRISM PRISM NNP cord-005646-xhx9pzhj 1760 8 , , , cord-005646-xhx9pzhj 1760 9 PRISM PRISM NNP cord-005646-xhx9pzhj 1760 10 - - HYPH cord-005646-xhx9pzhj 1760 11 II~ II~ NNP cord-005646-xhx9pzhj 1760 12 and and CC cord-005646-xhx9pzhj 1760 13 fISS fis NNS cord-005646-xhx9pzhj 1760 14 - - HYPH cord-005646-xhx9pzhj 1760 15 scores score NNS cord-005646-xhx9pzhj 1760 16 . . . cord-005646-xhx9pzhj 1761 1 Oxygen oxygen NN cord-005646-xhx9pzhj 1761 2 consumption consumption NN cord-005646-xhx9pzhj 1761 3 ( ( -LRB- cord-005646-xhx9pzhj 1761 4 VO2 VO2 NNP cord-005646-xhx9pzhj 1761 5 ) ) -RRB- cord-005646-xhx9pzhj 1761 6 , , , cord-005646-xhx9pzhj 1761 7 energy energy NN cord-005646-xhx9pzhj 1761 8 expenditure expenditure NN cord-005646-xhx9pzhj 1761 9 ( ( -LRB- cord-005646-xhx9pzhj 1761 10 MEE MEE NNP cord-005646-xhx9pzhj 1761 11 ) ) -RRB- cord-005646-xhx9pzhj 1761 12 and and CC cord-005646-xhx9pzhj 1761 13 respiratory respiratory JJ cord-005646-xhx9pzhj 1761 14 quotient quotient NN cord-005646-xhx9pzhj 1761 15 ( ( -LRB- cord-005646-xhx9pzhj 1761 16 RQ rq NN cord-005646-xhx9pzhj 1761 17 ) ) -RRB- cord-005646-xhx9pzhj 1761 18 were be VBD cord-005646-xhx9pzhj 1761 19 determmed determme VBN cord-005646-xhx9pzhj 1761 20 by by IN cord-005646-xhx9pzhj 1761 21 mdirect mdirect NN cord-005646-xhx9pzhj 1761 22 calorimetry calorimetry NN cord-005646-xhx9pzhj 1761 23 . . . cord-005646-xhx9pzhj 1762 1 Total total JJ cord-005646-xhx9pzhj 1762 2 urinary urinary JJ cord-005646-xhx9pzhj 1762 3 nitroger(TUN nitroger(tun CD cord-005646-xhx9pzhj 1762 4 ) ) -RRB- cord-005646-xhx9pzhj 1762 5 and and CC cord-005646-xhx9pzhj 1762 6 creatinine creatinine NN cord-005646-xhx9pzhj 1762 7 excretion excretion NN cord-005646-xhx9pzhj 1762 8 , , , cord-005646-xhx9pzhj 1762 9 levels level NNS cord-005646-xhx9pzhj 1762 10 of of IN cord-005646-xhx9pzhj 1762 11 albumin albumin NN cord-005646-xhx9pzhj 1762 12 and and CC cord-005646-xhx9pzhj 1762 13 CRP CRP NNP cord-005646-xhx9pzhj 1762 14 were be VBD cord-005646-xhx9pzhj 1762 15 aetermmed aetermme VBN cord-005646-xhx9pzhj 1762 16 in in IN cord-005646-xhx9pzhj 1762 17 16 16 CD cord-005646-xhx9pzhj 1762 18 patients patient NNS cord-005646-xhx9pzhj 1762 19 . . . cord-005646-xhx9pzhj 1763 1 In in IN cord-005646-xhx9pzhj 1763 2 these these DT cord-005646-xhx9pzhj 1763 3 patients patient NNS cord-005646-xhx9pzhj 1763 4 daily daily JJ cord-005646-xhx9pzhj 1763 5 caloric caloric JJ cord-005646-xhx9pzhj 1763 6 intake intake NN cord-005646-xhx9pzhj 1763 7 and and CC cord-005646-xhx9pzhj 1763 8 substrate substrate NN cord-005646-xhx9pzhj 1763 9 utilization utilization NN cord-005646-xhx9pzhj 1763 10 were be VBD cord-005646-xhx9pzhj 1763 11 assessed assess VBN cord-005646-xhx9pzhj 1763 12 . . . cord-005646-xhx9pzhj 1764 1 They -PRON- PRP cord-005646-xhx9pzhj 1764 2 were be VBD cord-005646-xhx9pzhj 1764 3 categorized categorize VBN cord-005646-xhx9pzhj 1764 4 in in IN cord-005646-xhx9pzhj 1764 5 subgroups subgroup NNS cord-005646-xhx9pzhj 1764 6 : : : cord-005646-xhx9pzhj 1764 7 A a DT cord-005646-xhx9pzhj 1764 8 partial partial JJ cord-005646-xhx9pzhj 1764 9 feeding feeding NN cord-005646-xhx9pzhj 1764 10 ( ( -LRB- cord-005646-xhx9pzhj 1764 11 recent recent JJ cord-005646-xhx9pzhj 1764 12 admission admission NN cord-005646-xhx9pzhj 1764 13 to to IN cord-005646-xhx9pzhj 1764 14 P1CU P1CU NNP cord-005646-xhx9pzhj 1764 15 ) ) -RRB- cord-005646-xhx9pzhj 1764 16 ; ; : cord-005646-xhx9pzhj 1764 17 B b LS cord-005646-xhx9pzhj 1764 18 complete complete JJ cord-005646-xhx9pzhj 1764 19 feeding feeding NN cord-005646-xhx9pzhj 1764 20 . . . cord-005646-xhx9pzhj 1765 1 Results result NNS cord-005646-xhx9pzhj 1765 2 : : : cord-005646-xhx9pzhj 1765 3 MEE MEE NNP cord-005646-xhx9pzhj 1765 4 of of IN cord-005646-xhx9pzhj 1765 5 the the DT cord-005646-xhx9pzhj 1765 6 total total JJ cord-005646-xhx9pzhj 1765 7 group group NN cord-005646-xhx9pzhj 1765 8 ( ( -LRB- cord-005646-xhx9pzhj 1765 9 n=37 n=37 NNP cord-005646-xhx9pzhj 1765 10 ) ) -RRB- cord-005646-xhx9pzhj 1765 11 _SP cord-005646-xhx9pzhj 1765 12 0A 0A NNP cord-005646-xhx9pzhj 1765 13 ) ) -RRB- cord-005646-xhx9pzhj 1766 1 I -PRON- PRP cord-005646-xhx9pzhj 1766 2 = = SYM cord-005646-xhx9pzhj 1766 3 intake intake NN cord-005646-xhx9pzhj 1766 4 g g NN cord-005646-xhx9pzhj 1766 5 / / SYM cord-005646-xhx9pzhj 1766 6 kg kg NNP cord-005646-xhx9pzhj 1766 7 / / SYM cord-005646-xhx9pzhj 1766 8 day day NN cord-005646-xhx9pzhj 1766 9 ( ( -LRB- cord-005646-xhx9pzhj 1766 10 % % NN cord-005646-xhx9pzhj 1766 11 total total JJ cord-005646-xhx9pzhj 1766 12 intake intake NN cord-005646-xhx9pzhj 1766 13 ) ) -RRB- cord-005646-xhx9pzhj 1766 14 ; ; : cord-005646-xhx9pzhj 1766 15 U u NN cord-005646-xhx9pzhj 1766 16 = = SYM cord-005646-xhx9pzhj 1766 17 utilization utilization NN cord-005646-xhx9pzhj 1766 18 g g NN cord-005646-xhx9pzhj 1766 19 / / SYM cord-005646-xhx9pzhj 1766 20 kg kg NNP cord-005646-xhx9pzhj 1766 21 / / SYM cord-005646-xhx9pzhj 1766 22 day day NN cord-005646-xhx9pzhj 1766 23 ( ( -LRB- cord-005646-xhx9pzhj 1766 24 % % NN cord-005646-xhx9pzhj 1766 25 total total JJ cord-005646-xhx9pzhj 1766 26 production production NN cord-005646-xhx9pzhj 1766 27 ) ) -RRB- cord-005646-xhx9pzhj 1766 28 . . . cord-005646-xhx9pzhj 1767 1 Nitrogenba]ance nitrogenba]ance NN cord-005646-xhx9pzhj 1767 2 was be VBD cord-005646-xhx9pzhj 1767 3 negative negative JJ cord-005646-xhx9pzhj 1767 4 in in IN cord-005646-xhx9pzhj 1767 5 all all DT cord-005646-xhx9pzhj 1767 6 patients patient NNS cord-005646-xhx9pzhj 1767 7 in in IN cord-005646-xhx9pzhj 1767 8 group group NN cord-005646-xhx9pzhj 1767 9 A A NNP cord-005646-xhx9pzhj 1767 10 ( ( -LRB- cord-005646-xhx9pzhj 1767 11 mean mean UH cord-005646-xhx9pzhj 1767 12 -227.7 -227.7 NFP cord-005646-xhx9pzhj 1767 13 --176:4 --176:4 NNP cord-005646-xhx9pzhj 1767 14 mffkg mffkg NNP cord-005646-xhx9pzhj 1767 15 / / SYM cord-005646-xhx9pzhj 1767 16 day day NN cord-005646-xhx9pzhj 1767 17 ) ) -RRB- cord-005646-xhx9pzhj 1767 18 and and CC cord-005646-xhx9pzhj 1767 19 positive positive JJ cord-005646-xhx9pzhj 1767 20 in in IN cord-005646-xhx9pzhj 1767 21 all all DT cord-005646-xhx9pzhj 1767 22 but but IN cord-005646-xhx9pzhj 1767 23 one one CD cord-005646-xhx9pzhj 1767 24 patient patient NN cord-005646-xhx9pzhj 1767 25 in in IN cord-005646-xhx9pzhj 1767 26 group group NN cord-005646-xhx9pzhj 1767 27 B B NNP cord-005646-xhx9pzhj 1768 1 ( ( -LRB- cord-005646-xhx9pzhj 1768 2 .mean .mean NNP cord-005646-xhx9pzhj 1768 3 84.9±109.D 84.9±109.d CD cord-005646-xhx9pzhj 1768 4 n n NN cord-005646-xhx9pzhj 1768 5 ~ ~ NFP cord-005646-xhx9pzhj 1768 6 g/ g/ NNP cord-005646-xhx9pzhj 1768 7 .. .. NFP cord-005646-xhx9pzhj 1768 8 kg kg NN cord-005646-xhx9pzhj 1768 9 / / SYM cord-005646-xhx9pzhj 1768 10 day;p=0.001 day;p=0.001 NNP cord-005646-xhx9pzhj 1768 11 ) ) -RRB- cord-005646-xhx9pzhj 1768 12 . . . cord-005646-xhx9pzhj 1769 1 No no DT cord-005646-xhx9pzhj 1769 2 significant significant JJ cord-005646-xhx9pzhj 1769 3 correlations correlation NNS cord-005646-xhx9pzhj 1769 4 were be VBD cord-005646-xhx9pzhj 1769 5 round round JJ cord-005646-xhx9pzhj 1769 6 between between IN cord-005646-xhx9pzhj 1769 7 creatinine creatinine NN cord-005646-xhx9pzhj 1769 8 height height NN cord-005646-xhx9pzhj 1769 9 index index NN cord-005646-xhx9pzhj 1769 10 , , , cord-005646-xhx9pzhj 1769 11 CRP CRP NNP cord-005646-xhx9pzhj 1769 12 , , , cord-005646-xhx9pzhj 1769 13 albumine albumine NN cord-005646-xhx9pzhj 1769 14 , , , cord-005646-xhx9pzhj 1769 15 JUN JUN NNP cord-005646-xhx9pzhj 1770 1 vs vs IN cord-005646-xhx9pzhj 1770 2 v v NNP cord-005646-xhx9pzhj 1771 1 u2 u2 NNP cord-005646-xhx9pzhj 1771 2 / / SYM cord-005646-xhx9pzhj 1771 3 Kg Kg NNP cord-005646-xhx9pzhj 1771 4 Conclusions Conclusions NNPS cord-005646-xhx9pzhj 1771 5 : : : cord-005646-xhx9pzhj 1772 1 The the DT cord-005646-xhx9pzhj 1772 2 mean mean NN cord-005646-xhx9pzhj 1772 3 measured measure VBN cord-005646-xhx9pzhj 1772 4 energy energy NN cord-005646-xhx9pzhj 1772 5 expenditure expenditure NN cord-005646-xhx9pzhj 1772 6 does do VBZ cord-005646-xhx9pzhj 1772 7 not not RB cord-005646-xhx9pzhj 1772 8 exceed exceed VB cord-005646-xhx9pzhj 1772 9 predicted predict VBN cord-005646-xhx9pzhj 1772 10 resting rest VBG cord-005646-xhx9pzhj 1772 11 energy energy NN cord-005646-xhx9pzhj 1772 12 expenditure expenditure NN cord-005646-xhx9pzhj 1772 13 , , , cord-005646-xhx9pzhj 1772 14 but but CC cord-005646-xhx9pzhj 1772 15 ~ere ~ere NNP cord-005646-xhx9pzhj 1772 16 is be VBZ cord-005646-xhx9pzhj 1772 17 a a DT cord-005646-xhx9pzhj 1772 18 wide wide JJ cord-005646-xhx9pzhj 1772 19 range range NN cord-005646-xhx9pzhj 1772 20 . . . cord-005646-xhx9pzhj 1773 1 In in IN cord-005646-xhx9pzhj 1773 2 a a DT cord-005646-xhx9pzhj 1773 3 majority majority NN cord-005646-xhx9pzhj 1773 4 ot ot IN cord-005646-xhx9pzhj 1773 5 patients patient NNS cord-005646-xhx9pzhj 1773 6 with with IN cord-005646-xhx9pzhj 1773 7 complete complete JJ cord-005646-xhx9pzhj 1773 8 feeding feeding NN cord-005646-xhx9pzhj 1773 9 h.igh h.igh NN cord-005646-xhx9pzhj 1773 10 carbohydrate carbohydrate NN cord-005646-xhx9pzhj 1773 11 intake intake NN cord-005646-xhx9pzhj 1773 12 resulted result VBD cord-005646-xhx9pzhj 1773 13 , , , cord-005646-xhx9pzhj 1773 14 in in IN cord-005646-xhx9pzhj 1773 15 High high JJ cord-005646-xhx9pzhj 1773 16 KQ KQ NNP cord-005646-xhx9pzhj 1773 17 and and CC cord-005646-xhx9pzhj 1773 18 lipogenesis lipogenesi NNS cord-005646-xhx9pzhj 1773 19 . . . cord-005646-xhx9pzhj 1774 1 In in IN cord-005646-xhx9pzhj 1774 2 patients patient NNS cord-005646-xhx9pzhj 1774 3 witla witla NNP cord-005646-xhx9pzhj 1774 4 partial partial JJ cord-005646-xhx9pzhj 1774 5 teeding teede VBG cord-005646-xhx9pzhj 1774 6 the the DT cord-005646-xhx9pzhj 1774 7 highly highly RB cord-005646-xhx9pzhj 1774 8 negatwe negatwe JJ cord-005646-xhx9pzhj 1775 1 nitrogen'balance nitrogen'balance NNP cord-005646-xhx9pzhj 1775 2 suggests suggest VBZ cord-005646-xhx9pzhj 1775 3 that that IN cord-005646-xhx9pzhj 1775 4 in in IN cord-005646-xhx9pzhj 1775 5 the the DT cord-005646-xhx9pzhj 1775 6 early early JJ cord-005646-xhx9pzhj 1775 7 phase phase NN cord-005646-xhx9pzhj 1775 8 of of IN cord-005646-xhx9pzhj 1775 9 diseasean diseasean JJ cord-005646-xhx9pzhj 1775 10 higher high JJR cord-005646-xhx9pzhj 1775 11 protein protein NN cord-005646-xhx9pzhj 1775 12 intake intake NN cord-005646-xhx9pzhj 1775 13 should should MD cord-005646-xhx9pzhj 1775 14 be be VB cord-005646-xhx9pzhj 1775 15 provided provide VBN cord-005646-xhx9pzhj 1775 16 . . . cord-005646-xhx9pzhj 1776 1 Severity severity NN cord-005646-xhx9pzhj 1776 2 of of IN cord-005646-xhx9pzhj 1776 3 illness illness NN cord-005646-xhx9pzhj 1776 4 scores score NNS cord-005646-xhx9pzhj 1776 5 ann ann NNP cord-005646-xhx9pzhj 1776 6 oiocnemicm oiocnemicm NNP cord-005646-xhx9pzhj 1776 7 markers marker NNS cord-005646-xhx9pzhj 1776 8 of of IN cord-005646-xhx9pzhj 1776 9 physiologic physiologic JJ cord-005646-xhx9pzhj 1776 10 stress stress NN cord-005646-xhx9pzhj 1776 11 correlatedpoorly correlatedpoorly RB cord-005646-xhx9pzhj 1776 12 with with IN cord-005646-xhx9pzhj 1776 13 oxygen oxygen NN cord-005646-xhx9pzhj 1776 14 consumption consumption NN cord-005646-xhx9pzhj 1776 15 . . . cord-005646-xhx9pzhj 1777 1 LEITE LEITE NNP cord-005646-xhx9pzhj 1777 2 , , , cord-005646-xhx9pzhj 1777 3 HP HP NNP cord-005646-xhx9pzhj 1777 4 ; ; : cord-005646-xhx9pzhj 1777 5 IGLESIAS IGLESIAS NNP cord-005646-xhx9pzhj 1777 6 , , , cord-005646-xhx9pzhj 1777 7 S S NNP cord-005646-xhx9pzhj 1777 8 ; ; : cord-005646-xhx9pzhj 1777 9 FARIA FARIA NNP cord-005646-xhx9pzhj 1777 10 , , , cord-005646-xhx9pzhj 1777 11 C C NNP cord-005646-xhx9pzhj 1777 12 ; ; : cord-005646-xhx9pzhj 1777 13 IKEDA IKEDA NNP cord-005646-xhx9pzhj 1777 14 , , , cord-005646-xhx9pzhj 1777 15 A A NNP cord-005646-xhx9pzhj 1777 16 ; ; : cord-005646-xhx9pzhj 1777 17 ALBUQUERQUE ALBUQUERQUE NNP cord-005646-xhx9pzhj 1777 18 , , , cord-005646-xhx9pzhj 1777 19 MP MP NNP cord-005646-xhx9pzhj 1777 20 ; ; : cord-005646-xhx9pzhj 1777 21 CARVALHO CARVALHO NNP cord-005646-xhx9pzhj 1777 22 , , , cord-005646-xhx9pzhj 1777 23 WB WB NNP cord-005646-xhx9pzhj 1777 24 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1777 25 ICU ICU NNP cord-005646-xhx9pzhj 1778 1 -S -S . cord-005646-xhx9pzhj 1779 1 ~o ~o NFP cord-005646-xhx9pzhj 1779 2 Paulo Paulo NNP cord-005646-xhx9pzhj 1779 3 Federal Federal NNP cord-005646-xhx9pzhj 1779 4 University University NNP cord-005646-xhx9pzhj 1780 1 -S -S . cord-005646-xhx9pzhj 1781 1 ~o ~o NFP cord-005646-xhx9pzhj 1781 2 Paulo Paulo NNP cord-005646-xhx9pzhj 1781 3 , , , cord-005646-xhx9pzhj 1781 4 Brazil Brazil NNP cord-005646-xhx9pzhj 1781 5 Objectives Objectives NNPS cord-005646-xhx9pzhj 1781 6 : : : cord-005646-xhx9pzhj 1781 7 1 1 CD cord-005646-xhx9pzhj 1781 8 ) ) -RRB- cord-005646-xhx9pzhj 1782 1 to to TO cord-005646-xhx9pzhj 1782 2 evaluate evaluate VB cord-005646-xhx9pzhj 1782 3 patterns pattern NNS cord-005646-xhx9pzhj 1782 4 of of IN cord-005646-xhx9pzhj 1782 5 use use NN cord-005646-xhx9pzhj 1782 6 and and CC cord-005646-xhx9pzhj 1782 7 monitoring monitoring NN cord-005646-xhx9pzhj 1782 8 of of IN cord-005646-xhx9pzhj 1782 9 nutritional nutritional JJ cord-005646-xhx9pzhj 1782 10 support support NN cord-005646-xhx9pzhj 1782 11 in in IN cord-005646-xhx9pzhj 1782 12 critically critically RB cord-005646-xhx9pzhj 1782 13 ill ill JJ cord-005646-xhx9pzhj 1782 14 children child NNS cord-005646-xhx9pzhj 1782 15 ; ; : cord-005646-xhx9pzhj 1782 16 2 2 LS cord-005646-xhx9pzhj 1782 17 ) ) -RRB- cord-005646-xhx9pzhj 1782 18 to to TO cord-005646-xhx9pzhj 1782 19 evaluate evaluate VB cord-005646-xhx9pzhj 1782 20 an an DT cord-005646-xhx9pzhj 1782 21 education education NN cord-005646-xhx9pzhj 1782 22 program program NN cord-005646-xhx9pzhj 1782 23 in in IN cord-005646-xhx9pzhj 1782 24 nutrition nutrition NN cord-005646-xhx9pzhj 1782 25 support support NN cord-005646-xhx9pzhj 1782 26 given give VBN cord-005646-xhx9pzhj 1782 27 throughout throughout IN cord-005646-xhx9pzhj 1782 28 the the DT cord-005646-xhx9pzhj 1782 29 resident resident JJ cord-005646-xhx9pzhj 1782 30 physician physician NN cord-005646-xhx9pzhj 1782 31 training training NN cord-005646-xhx9pzhj 1782 32 in in IN cord-005646-xhx9pzhj 1782 33 the the DT cord-005646-xhx9pzhj 1782 34 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1782 35 ICU ICU NNP cord-005646-xhx9pzhj 1782 36 . . . cord-005646-xhx9pzhj 1783 1 Patients patient NNS cord-005646-xhx9pzhj 1783 2 and and CC cord-005646-xhx9pzhj 1783 3 methods method NNS cord-005646-xhx9pzhj 1783 4 : : : cord-005646-xhx9pzhj 1783 5 records record NNS cord-005646-xhx9pzhj 1783 6 of of IN cord-005646-xhx9pzhj 1783 7 37 37 CD cord-005646-xhx9pzhj 1783 8 patients patient NNS cord-005646-xhx9pzhj 1783 9 receiving receive VBG cord-005646-xhx9pzhj 1783 10 nutritional nutritional JJ cord-005646-xhx9pzhj 1783 11 support support NN cord-005646-xhx9pzhj 1783 12 during during IN cord-005646-xhx9pzhj 1783 13 1993 1993 CD cord-005646-xhx9pzhj 1783 14 were be VBD cord-005646-xhx9pzhj 1783 15 reviewed review VBN cord-005646-xhx9pzhj 1783 16 . . . cord-005646-xhx9pzhj 1784 1 Aider Aider NNP cord-005646-xhx9pzhj 1784 2 this this DT cord-005646-xhx9pzhj 1784 3 first first JJ cord-005646-xhx9pzhj 1784 4 phase phase NN cord-005646-xhx9pzhj 1784 5 , , , cord-005646-xhx9pzhj 1784 6 knowledge knowledge NN cord-005646-xhx9pzhj 1784 7 and and CC cord-005646-xhx9pzhj 1784 8 understanding understanding NN cord-005646-xhx9pzhj 1784 9 of of IN cord-005646-xhx9pzhj 1784 10 the the DT cord-005646-xhx9pzhj 1784 11 role role NN cord-005646-xhx9pzhj 1784 12 of of IN cord-005646-xhx9pzhj 1784 13 nutrition nutrition NN cord-005646-xhx9pzhj 1784 14 support support NN cord-005646-xhx9pzhj 1784 15 was be VBD cord-005646-xhx9pzhj 1784 16 conveyed convey VBN cord-005646-xhx9pzhj 1784 17 to to IN cord-005646-xhx9pzhj 1784 18 the the DT cord-005646-xhx9pzhj 1784 19 residents resident NNS cord-005646-xhx9pzhj 1784 20 through through IN cord-005646-xhx9pzhj 1784 21 didactic didactic JJ cord-005646-xhx9pzhj 1784 22 lectures lecture NNS cord-005646-xhx9pzhj 1784 23 . . . cord-005646-xhx9pzhj 1785 1 In in IN cord-005646-xhx9pzhj 1785 2 a a DT cord-005646-xhx9pzhj 1785 3 second second JJ cord-005646-xhx9pzhj 1785 4 phase phase NN cord-005646-xhx9pzhj 1785 5 thedata thedata NNS cord-005646-xhx9pzhj 1785 6 were be VBD cord-005646-xhx9pzhj 1785 7 reevaluated reevaluate VBN cord-005646-xhx9pzhj 1785 8 in in IN cord-005646-xhx9pzhj 1785 9 35 35 CD cord-005646-xhx9pzhj 1785 10 children child NNS cord-005646-xhx9pzhj 1785 11 who who WP cord-005646-xhx9pzhj 1785 12 were be VBD cord-005646-xhx9pzhj 1785 13 given give VBN cord-005646-xhx9pzhj 1785 14 nutrition nutrition NN cord-005646-xhx9pzhj 1785 15 support support NN cord-005646-xhx9pzhj 1785 16 in in IN cord-005646-xhx9pzhj 1785 17 1995 1995 CD cord-005646-xhx9pzhj 1785 18 . . . cord-005646-xhx9pzhj 1786 1 Results result NNS cord-005646-xhx9pzhj 1786 2 : : : cord-005646-xhx9pzhj 1787 1 From from IN cord-005646-xhx9pzhj 1787 2 a a DT cord-005646-xhx9pzhj 1787 3 total total NN cord-005646-xhx9pzhj 1787 4 of of IN cord-005646-xhx9pzhj 1787 5 425 425 CD cord-005646-xhx9pzhj 1787 6 days day NNS cord-005646-xhx9pzhj 1787 7 ofthempy ofthempy NNP cord-005646-xhx9pzhj 1787 8 , , , cord-005646-xhx9pzhj 1787 9 the the DT cord-005646-xhx9pzhj 1787 10 single single JJ cord-005646-xhx9pzhj 1787 11 parenteral parenteral JJ cord-005646-xhx9pzhj 1787 12 route route NN cord-005646-xhx9pzhj 1787 13 was be VBD cord-005646-xhx9pzhj 1787 14 utilized utilize VBN cord-005646-xhx9pzhj 1787 15 in in IN cord-005646-xhx9pzhj 1787 16 80,5 80,5 CD cord-005646-xhx9pzhj 1787 17 % % NN cord-005646-xhx9pzhj 1787 18 , , , cord-005646-xhx9pzhj 1787 19 the the DT cord-005646-xhx9pzhj 1787 20 digestive digestive JJ cord-005646-xhx9pzhj 1787 21 route route NN cord-005646-xhx9pzhj 1787 22 ( ( -LRB- cord-005646-xhx9pzhj 1787 23 tube tube NN cord-005646-xhx9pzhj 1787 24 feeding feeding NN cord-005646-xhx9pzhj 1787 25 or or CC cord-005646-xhx9pzhj 1787 26 oral oral JJ cord-005646-xhx9pzhj 1787 27 route route NN cord-005646-xhx9pzhj 1787 28 ) ) -RRB- cord-005646-xhx9pzhj 1787 29 in in IN cord-005646-xhx9pzhj 1787 30 19,5 19,5 CD cord-005646-xhx9pzhj 1787 31 % % NN cord-005646-xhx9pzhj 1787 32 . . . cord-005646-xhx9pzhj 1788 1 of of IN cord-005646-xhx9pzhj 1788 2 this this DT cord-005646-xhx9pzhj 1788 3 time time NN cord-005646-xhx9pzhj 1788 4 . . . cord-005646-xhx9pzhj 1789 1 A a DT cord-005646-xhx9pzhj 1789 2 previous previous JJ cord-005646-xhx9pzhj 1789 3 nutr nutr NN cord-005646-xhx9pzhj 1789 4 ~ ~ NNP cord-005646-xhx9pzhj 1789 5 ional ional NNP cord-005646-xhx9pzhj 1789 6 assessment assessment NN cord-005646-xhx9pzhj 1789 7 was be VBD cord-005646-xhx9pzhj 1789 8 performed perform VBN cord-005646-xhx9pzhj 1789 9 in in IN cord-005646-xhx9pzhj 1789 10 3 3 CD cord-005646-xhx9pzhj 1789 11 children child NNS cord-005646-xhx9pzhj 1789 12 ; ; : cord-005646-xhx9pzhj 1789 13 no no DT cord-005646-xhx9pzhj 1789 14 patient patient NN cord-005646-xhx9pzhj 1789 15 had have VBD cord-005646-xhx9pzhj 1789 16 the the DT cord-005646-xhx9pzhj 1789 17 nutr nutr NNP cord-005646-xhx9pzhj 1789 18 ~ ~ NNP cord-005646-xhx9pzhj 1789 19 on on IN cord-005646-xhx9pzhj 1789 20 goals goal NNS cord-005646-xhx9pzhj 1789 21 set set VBN cord-005646-xhx9pzhj 1789 22 . . . cord-005646-xhx9pzhj 1790 1 The the DT cord-005646-xhx9pzhj 1790 2 nitrogen nitrogen NN cord-005646-xhx9pzhj 1790 3 to to IN cord-005646-xhx9pzhj 1790 4 nonprotein nonprotein NNP cord-005646-xhx9pzhj 1790 5 calories calorie NNS cord-005646-xhx9pzhj 1790 6 ratio ratio NN cord-005646-xhx9pzhj 1790 7 ranged range VBN cord-005646-xhx9pzhj 1790 8 among among IN cord-005646-xhx9pzhj 1790 9 1:80 1:80 CD cord-005646-xhx9pzhj 1790 10 and and CC cord-005646-xhx9pzhj 1790 11 1:250 1:250 CD cord-005646-xhx9pzhj 1790 12 . . . cord-005646-xhx9pzhj 1791 1 Only only RB cord-005646-xhx9pzhj 1791 2 29,7 29,7 CD cord-005646-xhx9pzhj 1791 3 % % NN cord-005646-xhx9pzhj 1791 4 of of IN cord-005646-xhx9pzhj 1791 5 the the DT cord-005646-xhx9pzhj 1791 6 patients patient NNS cord-005646-xhx9pzhj 1791 7 had have VBD cord-005646-xhx9pzhj 1791 8 their -PRON- PRP$ cord-005646-xhx9pzhj 1791 9 estimated estimate VBN cord-005646-xhx9pzhj 1791 10 caloric caloric JJ cord-005646-xhx9pzhj 1791 11 needs need NNS cord-005646-xhx9pzhj 1791 12 supplied supply VBN cord-005646-xhx9pzhj 1791 13 and and CC cord-005646-xhx9pzhj 1791 14 this this DT cord-005646-xhx9pzhj 1791 15 goal goal NN cord-005646-xhx9pzhj 1791 16 was be VBD cord-005646-xhx9pzhj 1791 17 achieved achieve VBN cord-005646-xhx9pzhj 1791 18 only only RB cord-005646-xhx9pzhj 1791 19 in in IN cord-005646-xhx9pzhj 1791 20 those those DT cord-005646-xhx9pzhj 1791 21 patients patient NNS cord-005646-xhx9pzhj 1791 22 who who WP cord-005646-xhx9pzhj 1791 23 were be VBD cord-005646-xhx9pzhj 1791 24 on on IN cord-005646-xhx9pzhj 1791 25 enteral enteral JJ cord-005646-xhx9pzhj 1791 26 tube tube NN cord-005646-xhx9pzhj 1791 27 feeding feeding NN cord-005646-xhx9pzhj 1791 28 . . . cord-005646-xhx9pzhj 1792 1 Patients patient NNS cord-005646-xhx9pzhj 1792 2 did do VBD cord-005646-xhx9pzhj 1792 3 not not RB cord-005646-xhx9pzhj 1792 4 achieved achieve VBN cord-005646-xhx9pzhj 1792 5 their -PRON- PRP$ cord-005646-xhx9pzhj 1792 6 goals goal NNS cord-005646-xhx9pzhj 1792 7 for for IN cord-005646-xhx9pzhj 1792 8 vitamins vitamin NNS cord-005646-xhx9pzhj 1792 9 . . . cord-005646-xhx9pzhj 1793 1 The the DT cord-005646-xhx9pzhj 1793 2 supply supply NN cord-005646-xhx9pzhj 1793 3 ofoligonleme ofoligonleme NN cord-005646-xhx9pzhj 1794 1 ~s ~s NNP cord-005646-xhx9pzhj 1794 2 was be VBD cord-005646-xhx9pzhj 1794 3 adequate adequate JJ cord-005646-xhx9pzhj 1794 4 except except IN cord-005646-xhx9pzhj 1794 5 the the DT cord-005646-xhx9pzhj 1794 6 zinc zinc NN cord-005646-xhx9pzhj 1794 7 . . . cord-005646-xhx9pzhj 1795 1 Nutritional nutritional JJ cord-005646-xhx9pzhj 1795 2 monitoring monitoring NN cord-005646-xhx9pzhj 1795 3 parameters parameter NNS cord-005646-xhx9pzhj 1795 4 including include VBG cord-005646-xhx9pzhj 1795 5 weight weight NN cord-005646-xhx9pzhj 1795 6 , , , cord-005646-xhx9pzhj 1795 7 serum serum NN cord-005646-xhx9pzhj 1795 8 albumin albumin NN cord-005646-xhx9pzhj 1795 9 and and CC cord-005646-xhx9pzhj 1795 10 serum serum NN cord-005646-xhx9pzhj 1795 11 triglycerides triglyceride NNS cord-005646-xhx9pzhj 1795 12 were be VBD cord-005646-xhx9pzhj 1795 13 performed perform VBN cord-005646-xhx9pzhj 1795 14 in in IN cord-005646-xhx9pzhj 1795 15 almost almost RB cord-005646-xhx9pzhj 1795 16 all all PDT cord-005646-xhx9pzhj 1795 17 the the DT cord-005646-xhx9pzhj 1795 18 patients patient NNS cord-005646-xhx9pzhj 1795 19 but but CC cord-005646-xhx9pzhj 1795 20 without without IN cord-005646-xhx9pzhj 1795 21 uniformity uniformity NN cord-005646-xhx9pzhj 1795 22 . . . cord-005646-xhx9pzhj 1796 1 The the DT cord-005646-xhx9pzhj 1796 2 reevaluation reevaluation NN cord-005646-xhx9pzhj 1796 3 ofthase ofthase IN cord-005646-xhx9pzhj 1796 4 parameters parameter NNS cord-005646-xhx9pzhj 1796 5 showed show VBD cord-005646-xhx9pzhj 1796 6 adequacy adequacy NN cord-005646-xhx9pzhj 1796 7 of of IN cord-005646-xhx9pzhj 1796 8 protein protein NN cord-005646-xhx9pzhj 1796 9 and and CC cord-005646-xhx9pzhj 1796 10 micronutrients micronutrient NNS cord-005646-xhx9pzhj 1796 11 supply supply NN cord-005646-xhx9pzhj 1796 12 ; ; : cord-005646-xhx9pzhj 1796 13 however however RB cord-005646-xhx9pzhj 1796 14 deficiency deficiency NN cord-005646-xhx9pzhj 1796 15 in in IN cord-005646-xhx9pzhj 1796 16 nutritional nutritional JJ cord-005646-xhx9pzhj 1796 17 monitoring monitoring NN cord-005646-xhx9pzhj 1796 18 and and CC cord-005646-xhx9pzhj 1796 19 infrequent infrequent JJ cord-005646-xhx9pzhj 1796 20 enteral enteral NN cord-005646-xhx9pzhj 1796 21 feeding feeding NN cord-005646-xhx9pzhj 1796 22 were be VBD cord-005646-xhx9pzhj 1796 23 still still RB cord-005646-xhx9pzhj 1796 24 detected detect VBN cord-005646-xhx9pzhj 1796 25 . . . cord-005646-xhx9pzhj 1797 1 Conclusion conclusion NN cord-005646-xhx9pzhj 1797 2 : : : cord-005646-xhx9pzhj 1798 1 There there EX cord-005646-xhx9pzhj 1798 2 were be VBD cord-005646-xhx9pzhj 1798 3 lacks lack NNS cord-005646-xhx9pzhj 1798 4 in in IN cord-005646-xhx9pzhj 1798 5 the the DT cord-005646-xhx9pzhj 1798 6 implementation implementation NN cord-005646-xhx9pzhj 1798 7 of of IN cord-005646-xhx9pzhj 1798 8 nutritional nutritional JJ cord-005646-xhx9pzhj 1798 9 support support NN cord-005646-xhx9pzhj 1798 10 , , , cord-005646-xhx9pzhj 1798 11 which which WDT cord-005646-xhx9pzhj 1798 12 were be VBD cord-005646-xhx9pzhj 1798 13 partially partially RB cord-005646-xhx9pzhj 1798 14 corrected correct VBN cord-005646-xhx9pzhj 1798 15 in in IN cord-005646-xhx9pzhj 1798 16 the the DT cord-005646-xhx9pzhj 1798 17 2rid 2rid CD cord-005646-xhx9pzhj 1798 18 phase phase NN cord-005646-xhx9pzhj 1798 19 of of IN cord-005646-xhx9pzhj 1798 20 the the DT cord-005646-xhx9pzhj 1798 21 study study NN cord-005646-xhx9pzhj 1798 22 , , , cord-005646-xhx9pzhj 1798 23 Although although IN cord-005646-xhx9pzhj 1798 24 the the DT cord-005646-xhx9pzhj 1798 25 training training NN cord-005646-xhx9pzhj 1798 26 of of IN cord-005646-xhx9pzhj 1798 27 residents resident NNS cord-005646-xhx9pzhj 1798 28 may may MD cord-005646-xhx9pzhj 1798 29 have have VB cord-005646-xhx9pzhj 1798 30 contributed contribute VBN cord-005646-xhx9pzhj 1798 31 to to TO cord-005646-xhx9pzhj 1798 32 give give VB cord-005646-xhx9pzhj 1798 33 them -PRON- PRP cord-005646-xhx9pzhj 1798 34 cognitive cognitive JJ cord-005646-xhx9pzhj 1798 35 skills skill NNS cord-005646-xhx9pzhj 1798 36 , , , cord-005646-xhx9pzhj 1798 37 it -PRON- PRP cord-005646-xhx9pzhj 1798 38 did do VBD cord-005646-xhx9pzhj 1798 39 n't not RB cord-005646-xhx9pzhj 1798 40 changed change VBN cord-005646-xhx9pzhj 1798 41 policies policy NNS cord-005646-xhx9pzhj 1798 42 and and CC cord-005646-xhx9pzhj 1798 43 procedures procedure NNS cord-005646-xhx9pzhj 1798 44 as as IN cord-005646-xhx9pzhj 1798 45 desired desire VBN cord-005646-xhx9pzhj 1798 46 . . . cord-005646-xhx9pzhj 1799 1 We -PRON- PRP cord-005646-xhx9pzhj 1799 2 recommend recommend VBP cord-005646-xhx9pzhj 1799 3 reinforcement reinforcement NN cord-005646-xhx9pzhj 1799 4 of of IN cord-005646-xhx9pzhj 1799 5 the the DT cord-005646-xhx9pzhj 1799 6 education education NN cord-005646-xhx9pzhj 1799 7 program program NN cord-005646-xhx9pzhj 1799 8 concerning concern VBG cord-005646-xhx9pzhj 1799 9 basic basic JJ cord-005646-xhx9pzhj 1799 10 nutritional nutritional JJ cord-005646-xhx9pzhj 1799 11 aspects aspect NNS cord-005646-xhx9pzhj 1799 12 , , , cord-005646-xhx9pzhj 1799 13 and and CC cord-005646-xhx9pzhj 1799 14 the the DT cord-005646-xhx9pzhj 1799 15 organization organization NN cord-005646-xhx9pzhj 1799 16 ofa ofa DT cord-005646-xhx9pzhj 1799 17 multidisciplinary multidisciplinary JJ cord-005646-xhx9pzhj 1799 18 team team NN cord-005646-xhx9pzhj 1799 19 in in IN cord-005646-xhx9pzhj 1799 20 charge charge NN cord-005646-xhx9pzhj 1799 21 of of IN cord-005646-xhx9pzhj 1799 22 coordinating coordinate VBG cord-005646-xhx9pzhj 1799 23 the the DT cord-005646-xhx9pzhj 1799 24 providing providing NN cord-005646-xhx9pzhj 1799 25 of of IN cord-005646-xhx9pzhj 1799 26 nutritional nutritional JJ cord-005646-xhx9pzhj 1799 27 support support NN cord-005646-xhx9pzhj 1799 28 . . . cord-005646-xhx9pzhj 1800 1 Plasme Plasme NNP cord-005646-xhx9pzhj 1800 2 free free JJ cord-005646-xhx9pzhj 1800 3 fatty fatty JJ cord-005646-xhx9pzhj 1800 4 acids acid NNS cord-005646-xhx9pzhj 1800 5 ( ( -LRB- cord-005646-xhx9pzhj 1800 6 FFA FFA NNP cord-005646-xhx9pzhj 1800 7 ) ) -RRB- cord-005646-xhx9pzhj 1801 1 are be VBP cord-005646-xhx9pzhj 1801 2 the the DT cord-005646-xhx9pzhj 1801 3 meier meier NNP cord-005646-xhx9pzhj 1801 4 energy energy NNP cord-005646-xhx9pzhj 1801 5 source source NN cord-005646-xhx9pzhj 1801 6 for for IN cord-005646-xhx9pzhj 1801 7 mast mast NN cord-005646-xhx9pzhj 1801 8 tissues tissue NNS cord-005646-xhx9pzhj 1801 9 . . . cord-005646-xhx9pzhj 1802 1 During during IN cord-005646-xhx9pzhj 1802 2 fasting fast VBG cord-005646-xhx9pzhj 1802 3 FFA FFA NNP cord-005646-xhx9pzhj 1802 4 are be VBP cord-005646-xhx9pzhj 1802 5 released release VBN cord-005646-xhx9pzhj 1802 6 from from IN cord-005646-xhx9pzhj 1802 7 the the DT cord-005646-xhx9pzhj 1802 8 breakdown breakdown NN cord-005646-xhx9pzhj 1802 9 af af NN cord-005646-xhx9pzhj 1802 10 triglycefides triglycefide VBZ cord-005646-xhx9pzhj 1802 11 in in IN cord-005646-xhx9pzhj 1802 12 edipose edipose NNP cord-005646-xhx9pzhj 1802 13 lissue lissue NNP cord-005646-xhx9pzhj 1802 14 ( ( -LRB- cord-005646-xhx9pzhj 1802 15 AT at NN cord-005646-xhx9pzhj 1802 16 ) ) -RRB- cord-005646-xhx9pzhj 1802 17 . . . cord-005646-xhx9pzhj 1803 1 Lipalysis Lipalysis NNP cord-005646-xhx9pzhj 1803 2 , , , cord-005646-xhx9pzhj 1803 3 Le Le NNP cord-005646-xhx9pzhj 1803 4 . . . cord-005646-xhx9pzhj 1804 1 the the DT cord-005646-xhx9pzhj 1804 2 rote rote NN cord-005646-xhx9pzhj 1804 3 of of IN cord-005646-xhx9pzhj 1804 4 release release NN cord-005646-xhx9pzhj 1804 5 o/ o/ NNP cord-005646-xhx9pzhj 1804 6 FFA FFA NNP cord-005646-xhx9pzhj 1804 7 , , , cord-005646-xhx9pzhj 1804 8 has have VBZ cord-005646-xhx9pzhj 1804 9 been be VBN cord-005646-xhx9pzhj 1804 10 meGsured megsure VBN cord-005646-xhx9pzhj 1804 11 in in IN cord-005646-xhx9pzhj 1804 12 humans human NNS cord-005646-xhx9pzhj 1804 13 by by IN cord-005646-xhx9pzhj 1804 14 means mean NNS cord-005646-xhx9pzhj 1804 15 of of IN cord-005646-xhx9pzhj 1804 16 stable stable JJ cord-005646-xhx9pzhj 1804 17 isotope isotope NN cord-005646-xhx9pzhj 1804 18 techniques technique NNS cord-005646-xhx9pzhj 1804 19 using use VBG cord-005646-xhx9pzhj 1804 20 labeled label VBN cord-005646-xhx9pzhj 1804 21 PA PA NNP cord-005646-xhx9pzhj 1804 22 or or CC cord-005646-xhx9pzhj 1804 23 glyeerd glyeerd NNP cord-005646-xhx9pzhj 1804 24 as as IN cord-005646-xhx9pzhj 1804 25 traces trace NNS cord-005646-xhx9pzhj 1804 26 . . . cord-005646-xhx9pzhj 1805 1 No no DT cord-005646-xhx9pzhj 1805 2 information information NN cord-005646-xhx9pzhj 1805 3 is be VBZ cord-005646-xhx9pzhj 1805 4 avoilob!e avoilob!e NNP cord-005646-xhx9pzhj 1806 1 Io Io NNP cord-005646-xhx9pzhj 1806 2 dale dale NNP cord-005646-xhx9pzhj 1806 3 on on IN cord-005646-xhx9pzhj 1806 4 the the DT cord-005646-xhx9pzhj 1806 5 Ro Ro NNP cord-005646-xhx9pzhj 1806 6 of of IN cord-005646-xhx9pzhj 1806 7 LA LA NNP cord-005646-xhx9pzhj 1806 8 . . . cord-005646-xhx9pzhj 1807 1 We -PRON- PRP cord-005646-xhx9pzhj 1807 2 infused infuse VBD cord-005646-xhx9pzhj 1807 3 albumin albumin NN cord-005646-xhx9pzhj 1807 4 hound hound NN cord-005646-xhx9pzhj 1807 5 U13C U13C NNP cord-005646-xhx9pzhj 1807 6 - - HYPH cord-005646-xhx9pzhj 1807 7 PA PA NNP cord-005646-xhx9pzhj 1807 8 and and CC cord-005646-xhx9pzhj 1807 9 U13C U13C NNP cord-005646-xhx9pzhj 1807 10 - - HYPH cord-005646-xhx9pzhj 1807 11 LA LA NNP cord-005646-xhx9pzhj 1807 12 in in IN cord-005646-xhx9pzhj 1807 13 7 7 CD cord-005646-xhx9pzhj 1807 14 critically critically RB cord-005646-xhx9pzhj 1807 15 ill ill JJ cord-005646-xhx9pzhj 1807 16 infants infant NNS cord-005646-xhx9pzhj 1807 17 , , , cord-005646-xhx9pzhj 1807 18 receiving receive VBG cord-005646-xhx9pzhj 1807 19 20 20 CD cord-005646-xhx9pzhj 1807 20 kcel kcel NNP cord-005646-xhx9pzhj 1807 21 / / SYM cord-005646-xhx9pzhj 1807 22 kg kg NNP cord-005646-xhx9pzhj 1807 23 / / SYM cord-005646-xhx9pzhj 1807 24 doy doy NNP cord-005646-xhx9pzhj 1807 25 of of IN cord-005646-xhx9pzhj 1807 26 IV IV NNP cord-005646-xhx9pzhj 1807 27 glucose glucose NN cord-005646-xhx9pzhj 1807 28 end end NN cord-005646-xhx9pzhj 1807 29 na na IN cord-005646-xhx9pzhj 1807 30 oral oral JJ cord-005646-xhx9pzhj 1807 31 feeding feeding NN cord-005646-xhx9pzhj 1807 32 ( ( -LRB- cord-005646-xhx9pzhj 1807 33 weight weight NN cord-005646-xhx9pzhj 1807 34 3.6,i 3.6,i CD cord-005646-xhx9pzhj 1807 35 . . . cord-005646-xhx9pzhj 1808 1 , , , cord-005646-xhx9pzhj 1808 2 3 3 CD cord-005646-xhx9pzhj 1809 1 kg kg NNS cord-005646-xhx9pzhj 1809 2 ; ; : cord-005646-xhx9pzhj 1809 3 , , , cord-005646-xhx9pzhj 1809 4 range range VBP cord-005646-xhx9pzhj 1809 5 1.9 1.9 CD cord-005646-xhx9pzhj 1809 6 - - HYPH cord-005646-xhx9pzhj 1809 7 5.8 5.8 CD cord-005646-xhx9pzhj 1809 8 ; ; : cord-005646-xhx9pzhj 1809 9 ego ego NN cord-005646-xhx9pzhj 1809 10 57:64 57:64 CD cord-005646-xhx9pzhj 1809 11 days day NNS cord-005646-xhx9pzhj 1809 12 , , , cord-005646-xhx9pzhj 1809 13 range range VBP cord-005646-xhx9pzhj 1809 14 1 1 CD cord-005646-xhx9pzhj 1809 15 149 149 CD cord-005646-xhx9pzhj 1809 16 ) ) -RRB- cord-005646-xhx9pzhj 1809 17 and and CC cord-005646-xhx9pzhj 1809 18 measured measure VBD cord-005646-xhx9pzhj 1809 19 simultaneously simultaneously RB cord-005646-xhx9pzhj 1809 20 the the DT cord-005646-xhx9pzhj 1809 21 Ra Ra NNP cord-005646-xhx9pzhj 1809 22 of of IN cord-005646-xhx9pzhj 1809 23 PA PA NNP cord-005646-xhx9pzhj 1809 24 and and CC cord-005646-xhx9pzhj 1809 25 LA LA NNP cord-005646-xhx9pzhj 1809 26 from from IN cord-005646-xhx9pzhj 1809 27 ( ( -LRB- cord-005646-xhx9pzhj 1809 28 he -PRON- PRP cord-005646-xhx9pzhj 1809 29 isotopic isotopic JJ cord-005646-xhx9pzhj 1809 30 enrichment enrichment NN cord-005646-xhx9pzhj 1809 31 of of IN cord-005646-xhx9pzhj 1809 32 plasma plasma NN cord-005646-xhx9pzhj 1809 33 FEA fea NN cord-005646-xhx9pzhj 1809 34 by by IN cord-005646-xhx9pzhj 1809 35 gas gas NN cord-005646-xhx9pzhj 1809 36 chromatography chromatography NN cord-005646-xhx9pzhj 1809 37 - - HYPH cord-005646-xhx9pzhj 1809 38 mass mass NN cord-005646-xhx9pzhj 1809 39 speclrome|ry speclrome|ry NN cord-005646-xhx9pzhj 1810 1 ai ai NNP cord-005646-xhx9pzhj 1811 1 1:50 1:50 CD cord-005646-xhx9pzhj 1811 2 , , , cord-005646-xhx9pzhj 1811 3 2:00 2:00 CD cord-005646-xhx9pzhj 1811 4 and and CC cord-005646-xhx9pzhj 1811 5 2:10 2:10 CD cord-005646-xhx9pzhj 1811 6 hours hour NNS cord-005646-xhx9pzhj 1811 7 from from IN cord-005646-xhx9pzhj 1811 8 tile tile NN cord-005646-xhx9pzhj 1811 9 shod shod NN cord-005646-xhx9pzhj 1811 10 of of IN cord-005646-xhx9pzhj 1811 11 the the DT cord-005646-xhx9pzhj 1811 12 infusion infusion NN cord-005646-xhx9pzhj 1811 13 . . . cord-005646-xhx9pzhj 1812 1 A a DT cord-005646-xhx9pzhj 1812 2 subcutaneous subcutaneous JJ cord-005646-xhx9pzhj 1812 3 gluted glut VBN cord-005646-xhx9pzhj 1812 4 AT at IN cord-005646-xhx9pzhj 1812 5 biopsy biopsy NN cord-005646-xhx9pzhj 1812 6 was be VBD cord-005646-xhx9pzhj 1812 7 obtained obtain VBN cord-005646-xhx9pzhj 1812 8 far far RB cord-005646-xhx9pzhj 1812 9 fatty fatty JJ cord-005646-xhx9pzhj 1812 10 acid acid NN cord-005646-xhx9pzhj 1812 11 ( ( -LRB- cord-005646-xhx9pzhj 1812 12 FA fa NN cord-005646-xhx9pzhj 1812 13 ) ) -RRB- cord-005646-xhx9pzhj 1812 14 composition composition NN cord-005646-xhx9pzhj 1812 15 . . . cord-005646-xhx9pzhj 1813 1 We -PRON- PRP cord-005646-xhx9pzhj 1813 2 intended intend VBD cord-005646-xhx9pzhj 1813 3 to to IN cord-005646-xhx9pzhj 1813 4 ( ( -LRB- cord-005646-xhx9pzhj 1813 5 1 1 CD cord-005646-xhx9pzhj 1813 6 ) ) -RRB- cord-005646-xhx9pzhj 1814 1 In in IN cord-005646-xhx9pzhj 1814 2 fie fie NNP cord-005646-xhx9pzhj 1814 3 infants infant NNS cord-005646-xhx9pzhj 1814 4 sbJdied sbjdie VBD cord-005646-xhx9pzhj 1814 5 ATIPA ATIPA NNP cord-005646-xhx9pzhj 1814 6 ~'os ~'os NFP cord-005646-xhx9pzhj 1814 7 hi9her hi9her NNP cord-005646-xhx9pzhj 1814 8 than than IN cord-005646-xhx9pzhj 1814 9 ATtLA ATtLA NNS cord-005646-xhx9pzhj 1815 1 ( ( -LRB- cord-005646-xhx9pzhj 1815 2 ~p ~p XX cord-005646-xhx9pzhj 1816 1 < < XX cord-005646-xhx9pzhj 1816 2 O.O01 O.O01 NNP cord-005646-xhx9pzhj 1816 3 ) ) -RRB- cord-005646-xhx9pzhj 1817 1 ' ' '' cord-005646-xhx9pzhj 1818 1 and and CC cord-005646-xhx9pzhj 1818 2 ihe ihe NNP cord-005646-xhx9pzhj 1818 3 Ra Ra NNP cord-005646-xhx9pzhj 1818 4 of of IN cord-005646-xhx9pzhj 1818 5 PA PA NNP cord-005646-xhx9pzhj 1818 6 was be VBD cord-005646-xhx9pzhj 1818 7 higher high JJR cord-005646-xhx9pzhj 1819 1 then then RB cord-005646-xhx9pzhj 1819 2 thai thai NNP cord-005646-xhx9pzhj 1819 3 of of IN cord-005646-xhx9pzhj 1819 4 LA LA NNP cord-005646-xhx9pzhj 1819 5 ( ( -LRB- cord-005646-xhx9pzhj 1819 6 ~p=0.00 ~p=0.00 NNP cord-005646-xhx9pzhj 1819 7 § § CD cord-005646-xhx9pzhj 1819 8 ) ) -RRB- cord-005646-xhx9pzhj 1819 9 . . . cord-005646-xhx9pzhj 1820 1 However however RB cord-005646-xhx9pzhj 1820 2 the the DT cord-005646-xhx9pzhj 1820 3 ratio ratio NN cord-005646-xhx9pzhj 1820 4 el el NNP cord-005646-xhx9pzhj 1820 5 the the DT cord-005646-xhx9pzhj 1820 6 Re Re NNP cord-005646-xhx9pzhj 1820 7 's 's POS cord-005646-xhx9pzhj 1820 8 to to IN cord-005646-xhx9pzhj 1820 9 the the DT cord-005646-xhx9pzhj 1820 10 respecLive respeclive JJ cord-005646-xhx9pzhj 1820 11 FA fa NN cord-005646-xhx9pzhj 1820 12 in in IN cord-005646-xhx9pzhj 1820 13 AT AT NNP cord-005646-xhx9pzhj 1820 14 was be VBD cord-005646-xhx9pzhj 1820 15 higher high JJR cord-005646-xhx9pzhj 1820 16 for for IN cord-005646-xhx9pzhj 1820 17 LA LA NNP cord-005646-xhx9pzhj 1820 18 than than IN cord-005646-xhx9pzhj 1820 19 far far RB cord-005646-xhx9pzhj 1820 20 PA PA NNP cord-005646-xhx9pzhj 1820 21 ( ( -LRB- cord-005646-xhx9pzhj 1820 22 * * NFP cord-005646-xhx9pzhj 1820 23 p=0.02 p=0.02 NN cord-005646-xhx9pzhj 1820 24 ) ) -RRB- cord-005646-xhx9pzhj 1820 25 . . . cord-005646-xhx9pzhj 1821 1 In in IN cord-005646-xhx9pzhj 1821 2 conclusion conclusion NN cord-005646-xhx9pzhj 1821 3 the the DT cord-005646-xhx9pzhj 1821 4 Ra Ra NNP cord-005646-xhx9pzhj 1821 5 af af NNP cord-005646-xhx9pzhj 1821 6 LA LA NNP cord-005646-xhx9pzhj 1821 7 was be VBD cord-005646-xhx9pzhj 1821 8 higher high JJR cord-005646-xhx9pzhj 1821 9 then then RB cord-005646-xhx9pzhj 1821 10 expected expect VBN cord-005646-xhx9pzhj 1821 11 from from IN cord-005646-xhx9pzhj 1821 12 ~he ~he JJ cord-005646-xhx9pzhj 1821 13 FA FA NNP cord-005646-xhx9pzhj 1821 14 composition composition NN cord-005646-xhx9pzhj 1821 15 of of IN cord-005646-xhx9pzhj 1821 16 AT AT NNP cord-005646-xhx9pzhj 1821 17 . . . cord-005646-xhx9pzhj 1822 1 We -PRON- PRP cord-005646-xhx9pzhj 1822 2 speculate speculate VBP cord-005646-xhx9pzhj 1822 3 [ [ -LRB- cord-005646-xhx9pzhj 1822 4 hat hat NN cord-005646-xhx9pzhj 1822 5 LA LA NNP cord-005646-xhx9pzhj 1822 6 is be VBZ cord-005646-xhx9pzhj 1822 7 preferentially preferentially RB cord-005646-xhx9pzhj 1822 8 released release VBN cord-005646-xhx9pzhj 1822 9 during during IN cord-005646-xhx9pzhj 1822 10 tipolysis tipolysis NNP cord-005646-xhx9pzhj 1822 11 and and CC cord-005646-xhx9pzhj 1822 12 its -PRON- PRP$ cord-005646-xhx9pzhj 1822 13 contributuion contributuion NN cord-005646-xhx9pzhj 1822 14 to to IN cord-005646-xhx9pzhj 1822 15 the the DT cord-005646-xhx9pzhj 1822 16 energy energy NN cord-005646-xhx9pzhj 1822 17 metnbolism metnbolism NN cord-005646-xhx9pzhj 1822 18 of of IN cord-005646-xhx9pzhj 1822 19 the the DT cord-005646-xhx9pzhj 1822 20 sick sick JJ cord-005646-xhx9pzhj 1822 21 infonl infonl NN cord-005646-xhx9pzhj 1822 22 could could MD cord-005646-xhx9pzhj 1822 23 Io Io NNP cord-005646-xhx9pzhj 1822 24 ! ! . cord-005646-xhx9pzhj 1823 1 orger orger NNP cord-005646-xhx9pzhj 1823 2 than than IN cord-005646-xhx9pzhj 1823 3 what what WP cord-005646-xhx9pzhj 1823 4 : : : cord-005646-xhx9pzhj 1823 5 is be VBZ cord-005646-xhx9pzhj 1823 6 normaI!y normaI!y NNP cord-005646-xhx9pzhj 1823 7 assumed assume VBN cord-005646-xhx9pzhj 1823 8 from from IN cord-005646-xhx9pzhj 1823 9 Ihe Ihe NNP cord-005646-xhx9pzhj 1823 10 FA FA NNP cord-005646-xhx9pzhj 1823 11 composilion composilion NN cord-005646-xhx9pzhj 1823 12 of of IN cord-005646-xhx9pzhj 1823 13 AT AT NNP cord-005646-xhx9pzhj 1823 14 and and CC cord-005646-xhx9pzhj 1823 15 of of IN cord-005646-xhx9pzhj 1823 16 plasma plasma NN cord-005646-xhx9pzhj 1823 17 FEA fea NN cord-005646-xhx9pzhj 1823 18 . . . cord-005646-xhx9pzhj 1824 1 Preoperative preoperative JJ cord-005646-xhx9pzhj 1824 2 starvation starvation NN cord-005646-xhx9pzhj 1824 3 can can MD cord-005646-xhx9pzhj 1824 4 be be VB cord-005646-xhx9pzhj 1824 5 prevented prevent VBN cord-005646-xhx9pzhj 1824 6 in in IN cord-005646-xhx9pzhj 1824 7 infants infant NNS cord-005646-xhx9pzhj 1824 8 undergoing undergo VBG cord-005646-xhx9pzhj 1824 9 non non JJ cord-005646-xhx9pzhj 1824 10 GI gi NN cord-005646-xhx9pzhj 1824 11 surgery surgery NN cord-005646-xhx9pzhj 1824 12 by by IN cord-005646-xhx9pzhj 1824 13 continuing continue VBG cord-005646-xhx9pzhj 1824 14 feeds feed NNS cord-005646-xhx9pzhj 1824 15 till till IN cord-005646-xhx9pzhj 1824 16 as as RB cord-005646-xhx9pzhj 1824 17 long long RB cord-005646-xhx9pzhj 1824 18 as as IN cord-005646-xhx9pzhj 1824 19 it -PRON- PRP cord-005646-xhx9pzhj 1824 20 is be VBZ cord-005646-xhx9pzhj 1824 21 safe safe JJ cord-005646-xhx9pzhj 1824 22 to to TO cord-005646-xhx9pzhj 1824 23 do do VB cord-005646-xhx9pzhj 1824 24 so so RB cord-005646-xhx9pzhj 1824 25 . . . cord-005646-xhx9pzhj 1825 1 Some some DT cord-005646-xhx9pzhj 1825 2 GI GI NNP cord-005646-xhx9pzhj 1825 3 disorders disorder NNS cord-005646-xhx9pzhj 1825 4 require require VBP cord-005646-xhx9pzhj 1825 5 withholding withholding NN cord-005646-xhx9pzhj 1825 6 of of IN cord-005646-xhx9pzhj 1825 7 feeds feed NNS cord-005646-xhx9pzhj 1825 8 for for IN cord-005646-xhx9pzhj 1825 9 a a DT cord-005646-xhx9pzhj 1825 10 long long JJ cord-005646-xhx9pzhj 1825 11 period period NN cord-005646-xhx9pzhj 1825 12 . . . cord-005646-xhx9pzhj 1826 1 For for IN cord-005646-xhx9pzhj 1826 2 these these DT cord-005646-xhx9pzhj 1826 3 and and CC cord-005646-xhx9pzhj 1826 4 for for IN cord-005646-xhx9pzhj 1826 5 infants infant NNS cord-005646-xhx9pzhj 1826 6 already already RB cord-005646-xhx9pzhj 1826 7 suffering suffer VBG cord-005646-xhx9pzhj 1826 8 from from IN cord-005646-xhx9pzhj 1826 9 PEM~ PEM~ NNP cord-005646-xhx9pzhj 1826 10 parenteral parenteral JJ cord-005646-xhx9pzhj 1826 11 feeds feed NNS cord-005646-xhx9pzhj 1826 12 are be VBP cord-005646-xhx9pzhj 1826 13 given give VBN cord-005646-xhx9pzhj 1826 14 preoperatively preoperatively NN cord-005646-xhx9pzhj 1826 15 . . . cord-005646-xhx9pzhj 1827 1 Peroperatively peroperatively JJ cord-005646-xhx9pzhj 1827 2 nutrition nutrition NN cord-005646-xhx9pzhj 1827 3 is be VBZ cord-005646-xhx9pzhj 1827 4 maintained maintain VBN cord-005646-xhx9pzhj 1827 5 by by IN cord-005646-xhx9pzhj 1827 6 ensuring ensure VBG cord-005646-xhx9pzhj 1827 7 adequate adequate JJ cord-005646-xhx9pzhj 1827 8 glucose glucose NN cord-005646-xhx9pzhj 1827 9 supply supply NN cord-005646-xhx9pzhj 1827 10 in in IN cord-005646-xhx9pzhj 1827 11 the the DT cord-005646-xhx9pzhj 1827 12 infusion infusion NN cord-005646-xhx9pzhj 1827 13 fluid fluid NN cord-005646-xhx9pzhj 1827 14 and and CC cord-005646-xhx9pzhj 1827 15 its -PRON- PRP$ cord-005646-xhx9pzhj 1827 16 smooth smooth JJ cord-005646-xhx9pzhj 1827 17 metabolism metabolism NN cord-005646-xhx9pzhj 1827 18 . . . cord-005646-xhx9pzhj 1828 1 Proper proper JJ cord-005646-xhx9pzhj 1828 2 placement placement NN cord-005646-xhx9pzhj 1828 3 of of IN cord-005646-xhx9pzhj 1828 4 feeding feed VBG cord-005646-xhx9pzhj 1828 5 tubes tube NNS cord-005646-xhx9pzhj 1828 6 are be VBP cord-005646-xhx9pzhj 1828 7 also also RB cord-005646-xhx9pzhj 1828 8 carried carry VBN cord-005646-xhx9pzhj 1828 9 out out RP cord-005646-xhx9pzhj 1828 10 peroperatively peroperatively RB cord-005646-xhx9pzhj 1828 11 . . . cord-005646-xhx9pzhj 1829 1 Postoperative postoperative JJ cord-005646-xhx9pzhj 1829 2 early early JJ cord-005646-xhx9pzhj 1829 3 resumption resumption NN cord-005646-xhx9pzhj 1829 4 of of IN cord-005646-xhx9pzhj 1829 5 oral oral JJ cord-005646-xhx9pzhj 1829 6 feeds feed NNS cord-005646-xhx9pzhj 1829 7 is be VBZ cord-005646-xhx9pzhj 1829 8 ensured ensure VBN cord-005646-xhx9pzhj 1829 9 by by IN cord-005646-xhx9pzhj 1829 10 new new JJ cord-005646-xhx9pzhj 1829 11 techniques technique NNS cord-005646-xhx9pzhj 1829 12 of of IN cord-005646-xhx9pzhj 1829 13 anaesthesia anaesthesia NN cord-005646-xhx9pzhj 1829 14 and and CC cord-005646-xhx9pzhj 1829 15 pain pain NN cord-005646-xhx9pzhj 1829 16 relief relief NN cord-005646-xhx9pzhj 1829 17 and and CC cord-005646-xhx9pzhj 1829 18 methods method NNS cord-005646-xhx9pzhj 1829 19 to to TO cord-005646-xhx9pzhj 1829 20 ensure ensure VB cord-005646-xhx9pzhj 1829 21 early early JJ cord-005646-xhx9pzhj 1829 22 return return NN cord-005646-xhx9pzhj 1829 23 of of IN cord-005646-xhx9pzhj 1829 24 peristalsis peristalsis NN cord-005646-xhx9pzhj 1829 25 . . . cord-005646-xhx9pzhj 1830 1 Enteral enteral NN cord-005646-xhx9pzhj 1830 2 feeds feed NNS cord-005646-xhx9pzhj 1830 3 of of IN cord-005646-xhx9pzhj 1830 4 pre pre JJ cord-005646-xhx9pzhj 1830 5 digested digested JJ cord-005646-xhx9pzhj 1830 6 substances substance NNS cord-005646-xhx9pzhj 1830 7 and and CC cord-005646-xhx9pzhj 1830 8 feeds feed VBZ cord-005646-xhx9pzhj 1830 9 through through IN cord-005646-xhx9pzhj 1830 10 transanastomotic transanastomotic JJ cord-005646-xhx9pzhj 1830 11 tubes tube NNS cord-005646-xhx9pzhj 1830 12 and and CC cord-005646-xhx9pzhj 1830 13 through through IN cord-005646-xhx9pzhj 1830 14 gastrostomies gastrostomy NNS cord-005646-xhx9pzhj 1830 15 and and CC cord-005646-xhx9pzhj 1830 16 jejunostomies jejunostomy NNS cord-005646-xhx9pzhj 1830 17 can can MD cord-005646-xhx9pzhj 1830 18 prevent prevent VB cord-005646-xhx9pzhj 1830 19 starvation starvation NN cord-005646-xhx9pzhj 1830 20 in in IN cord-005646-xhx9pzhj 1830 21 many many JJ cord-005646-xhx9pzhj 1830 22 situations situation NNS cord-005646-xhx9pzhj 1830 23 . . . cord-005646-xhx9pzhj 1831 1 Parenteral parenteral JJ cord-005646-xhx9pzhj 1831 2 feeding feeding NN cord-005646-xhx9pzhj 1831 3 is be VBZ cord-005646-xhx9pzhj 1831 4 carried carry VBN cord-005646-xhx9pzhj 1831 5 out out RP cord-005646-xhx9pzhj 1831 6 only only RB cord-005646-xhx9pzhj 1831 7 when when WRB cord-005646-xhx9pzhj 1831 8 enteral enteral JJ cord-005646-xhx9pzhj 1831 9 feeding feeding NN cord-005646-xhx9pzhj 1831 10 is be VBZ cord-005646-xhx9pzhj 1831 11 not not RB cord-005646-xhx9pzhj 1831 12 possible possible JJ cord-005646-xhx9pzhj 1831 13 , , , cord-005646-xhx9pzhj 1831 14 for for IN cord-005646-xhx9pzhj 1831 15 example example NN cord-005646-xhx9pzhj 1831 16 in in IN cord-005646-xhx9pzhj 1831 17 necrotising necrotising NNP cord-005646-xhx9pzhj 1832 1 enterocolitis~ enterocolitis~ NNP cord-005646-xhx9pzhj 1833 1 gastroschisis gastroschisis NNP cord-005646-xhx9pzhj 1833 2 , , , cord-005646-xhx9pzhj 1833 3 short short JJ cord-005646-xhx9pzhj 1833 4 gut gut NN cord-005646-xhx9pzhj 1833 5 syndrome syndrome NN cord-005646-xhx9pzhj 1833 6 , , , cord-005646-xhx9pzhj 1833 7 high high JJ cord-005646-xhx9pzhj 1833 8 enteric enteric JJ cord-005646-xhx9pzhj 1833 9 fistula fistula NN cord-005646-xhx9pzhj 1833 10 and and CC cord-005646-xhx9pzhj 1833 11 acute acute JJ cord-005646-xhx9pzhj 1833 12 pancreatltls pancreatltls NN cord-005646-xhx9pzhj 1833 13 . . . cord-005646-xhx9pzhj 1834 1 The the DT cord-005646-xhx9pzhj 1834 2 artedal artedal JJ cord-005646-xhx9pzhj 1834 3 ketone ketone NN cord-005646-xhx9pzhj 1834 4 body body NN cord-005646-xhx9pzhj 1834 5 ratio ratio NN cord-005646-xhx9pzhj 1834 6 ( ( -LRB- cord-005646-xhx9pzhj 1834 7 AKBR AKBR NNP cord-005646-xhx9pzhj 1834 8 ) ) -RRB- cord-005646-xhx9pzhj 1834 9 is be VBZ cord-005646-xhx9pzhj 1834 10 established establish VBN cord-005646-xhx9pzhj 1834 11 as as IN cord-005646-xhx9pzhj 1834 12 a a DT cord-005646-xhx9pzhj 1834 13 valuable valuable JJ cord-005646-xhx9pzhj 1834 14 tool tool NN cord-005646-xhx9pzhj 1834 15 in in IN cord-005646-xhx9pzhj 1834 16 the the DT cord-005646-xhx9pzhj 1834 17 management management NN cord-005646-xhx9pzhj 1834 18 of of IN cord-005646-xhx9pzhj 1834 19 adult adult NN cord-005646-xhx9pzhj 1834 20 patients patient NNS cord-005646-xhx9pzhj 1834 21 undergoing undergo VBG cord-005646-xhx9pzhj 1834 22 surgery surgery NN cord-005646-xhx9pzhj 1834 23 for for IN cord-005646-xhx9pzhj 1834 24 severe severe JJ cord-005646-xhx9pzhj 1834 25 liver liver NN cord-005646-xhx9pzhj 1834 26 disease disease NN cord-005646-xhx9pzhj 1834 27 . . . cord-005646-xhx9pzhj 1835 1 The the DT cord-005646-xhx9pzhj 1835 2 redox redox NN cord-005646-xhx9pzhj 1835 3 theory theory NN cord-005646-xhx9pzhj 1835 4 emphasises emphasise VBZ cord-005646-xhx9pzhj 1835 5 the the DT cord-005646-xhx9pzhj 1835 6 central central JJ cord-005646-xhx9pzhj 1835 7 role role NN cord-005646-xhx9pzhj 1835 8 of of IN cord-005646-xhx9pzhj 1835 9 the the DT cord-005646-xhx9pzhj 1835 10 liver liver NN cord-005646-xhx9pzhj 1835 11 in in IN cord-005646-xhx9pzhj 1835 12 preserving preserve VBG cord-005646-xhx9pzhj 1835 13 homeostasis homeostasis NN cord-005646-xhx9pzhj 1835 14 and and CC cord-005646-xhx9pzhj 1835 15 the the DT cord-005646-xhx9pzhj 1835 16 importance importance NN cord-005646-xhx9pzhj 1835 17 of of IN cord-005646-xhx9pzhj 1835 18 the the DT cord-005646-xhx9pzhj 1835 19 hepatic hepatic JJ cord-005646-xhx9pzhj 1835 20 mitochonddal mitochonddal JJ cord-005646-xhx9pzhj 1835 21 redox redox NN cord-005646-xhx9pzhj 1835 22 potential potential NN cord-005646-xhx9pzhj 1835 23 ( ( -LRB- cord-005646-xhx9pzhj 1835 24 NAD+/NADH NAD+/NADH NNP cord-005646-xhx9pzhj 1835 25 ) ) -RRB- cord-005646-xhx9pzhj 1835 26 in in IN cord-005646-xhx9pzhj 1835 27 monitoring monitor VBG cord-005646-xhx9pzhj 1835 28 liver liver NN cord-005646-xhx9pzhj 1835 29 function function NN cord-005646-xhx9pzhj 1835 30 and and CC cord-005646-xhx9pzhj 1835 31 integrity integrity NN cord-005646-xhx9pzhj 1835 32 . . . cord-005646-xhx9pzhj 1836 1 The the DT cord-005646-xhx9pzhj 1836 2 AKBR AKBR NNP cord-005646-xhx9pzhj 1836 3 ( ( -LRB- cord-005646-xhx9pzhj 1836 4 plasma plasma NN cord-005646-xhx9pzhj 1836 5 acetoacetate/3hydroxybutyrate acetoacetate/3hydroxybutyrate NN cord-005646-xhx9pzhj 1836 6 ) ) -RRB- cord-005646-xhx9pzhj 1836 7 is be VBZ cord-005646-xhx9pzhj 1836 8 a a DT cord-005646-xhx9pzhj 1836 9 measure measure NN cord-005646-xhx9pzhj 1836 10 of of IN cord-005646-xhx9pzhj 1836 11 hepatic hepatic JJ cord-005646-xhx9pzhj 1836 12 mitochonddal mitochonddal JJ cord-005646-xhx9pzhj 1836 13 redox redox JJ cord-005646-xhx9pzhj 1836 14 status status NN cord-005646-xhx9pzhj 1836 15 , , , cord-005646-xhx9pzhj 1836 16 reduced reduce VBN cord-005646-xhx9pzhj 1836 17 ratios ratio NNS cord-005646-xhx9pzhj 1836 18 associated associate VBN cord-005646-xhx9pzhj 1836 19 with with IN cord-005646-xhx9pzhj 1836 20 poorer poor JJR cord-005646-xhx9pzhj 1836 21 outcome outcome NN cord-005646-xhx9pzhj 1836 22 . . . cord-005646-xhx9pzhj 1837 1 The the DT cord-005646-xhx9pzhj 1837 2 venous venous JJ cord-005646-xhx9pzhj 1837 3 ketone ketone NN cord-005646-xhx9pzhj 1837 4 body body NN cord-005646-xhx9pzhj 1837 5 ratio ratio NN cord-005646-xhx9pzhj 1837 6 ( ( -LRB- cord-005646-xhx9pzhj 1837 7 VKBR VKBR NNP cord-005646-xhx9pzhj 1837 8 ) ) -RRB- cord-005646-xhx9pzhj 1837 9 is be VBZ cord-005646-xhx9pzhj 1837 10 influenced influence VBN cord-005646-xhx9pzhj 1837 11 by by IN cord-005646-xhx9pzhj 1837 12 peripheral peripheral JJ cord-005646-xhx9pzhj 1837 13 ketone ketone NN cord-005646-xhx9pzhj 1837 14 utilisation utilisation NN cord-005646-xhx9pzhj 1837 15 and and CC cord-005646-xhx9pzhj 1837 16 therefore therefore RB cord-005646-xhx9pzhj 1837 17 thought think VBD cord-005646-xhx9pzhj 1837 18 unreliable unreliable JJ cord-005646-xhx9pzhj 1837 19 in in IN cord-005646-xhx9pzhj 1837 20 assessing assess VBG cord-005646-xhx9pzhj 1837 21 hepatic hepatic JJ cord-005646-xhx9pzhj 1837 22 redox redox NN cord-005646-xhx9pzhj 1838 1 Its -PRON- PRP$ cord-005646-xhx9pzhj 1838 2 use use NN cord-005646-xhx9pzhj 1838 3 has have VBZ cord-005646-xhx9pzhj 1838 4 been be VBN cord-005646-xhx9pzhj 1838 5 dismissed dismiss VBN cord-005646-xhx9pzhj 1838 6 as as IN cord-005646-xhx9pzhj 1838 7 no no DT cord-005646-xhx9pzhj 1838 8 correlation correlation NN cord-005646-xhx9pzhj 1838 9 with with IN cord-005646-xhx9pzhj 1838 10 the the DT cord-005646-xhx9pzhj 1838 11 ratio ratio NN cord-005646-xhx9pzhj 1838 12 in in IN cord-005646-xhx9pzhj 1838 13 hepatic hepatic JJ cord-005646-xhx9pzhj 1838 14 venous venous JJ cord-005646-xhx9pzhj 1838 15 blood blood NN cord-005646-xhx9pzhj 1838 16 was be VBD cord-005646-xhx9pzhj 1838 17 found find VBN cord-005646-xhx9pzhj 1838 18 . . . cord-005646-xhx9pzhj 1839 1 Inspite inspite NN cord-005646-xhx9pzhj 1839 2 of of IN cord-005646-xhx9pzhj 1839 3 this this DT cord-005646-xhx9pzhj 1839 4 . . . cord-005646-xhx9pzhj 1840 1 VKBR VKBR NNP cord-005646-xhx9pzhj 1840 2 is be VBZ cord-005646-xhx9pzhj 1840 3 used use VBN cord-005646-xhx9pzhj 1840 4 in in IN cord-005646-xhx9pzhj 1840 5 the the DT cord-005646-xhx9pzhj 1840 6 diagnosis diagnosis NN cord-005646-xhx9pzhj 1840 7 of of IN cord-005646-xhx9pzhj 1840 8 lactic lactic JJ cord-005646-xhx9pzhj 1840 9 acidoses acidose NNS cord-005646-xhx9pzhj 1840 10 and and CC cord-005646-xhx9pzhj 1840 11 respiratory respiratory JJ cord-005646-xhx9pzhj 1840 12 chain chain NN cord-005646-xhx9pzhj 1840 13 defects defect NNS cord-005646-xhx9pzhj 1840 14 . . . cord-005646-xhx9pzhj 1841 1 The the DT cord-005646-xhx9pzhj 1841 2 objective objective NN cord-005646-xhx9pzhj 1841 3 of of IN cord-005646-xhx9pzhj 1841 4 this this DT cord-005646-xhx9pzhj 1841 5 study study NN cord-005646-xhx9pzhj 1841 6 was be VBD cord-005646-xhx9pzhj 1841 7 to to TO cord-005646-xhx9pzhj 1841 8 determine determine VB cord-005646-xhx9pzhj 1841 9 the the DT cord-005646-xhx9pzhj 1841 10 relationship relationship NN cord-005646-xhx9pzhj 1841 11 between between IN cord-005646-xhx9pzhj 1841 12 the the DT cord-005646-xhx9pzhj 1841 13 AKBR AKBR NNP cord-005646-xhx9pzhj 1841 14 and and CC cord-005646-xhx9pzhj 1841 15 VKBR VKBR NNP cord-005646-xhx9pzhj 1841 16 in in IN cord-005646-xhx9pzhj 1841 17 a a DT cord-005646-xhx9pzhj 1841 18 paediatnc paediatnc NN cord-005646-xhx9pzhj 1841 19 intensive intensive JJ cord-005646-xhx9pzhj 1841 20 care care NN cord-005646-xhx9pzhj 1841 21 population population NN cord-005646-xhx9pzhj 1841 22 . . . cord-005646-xhx9pzhj 1842 1 31 31 CD cord-005646-xhx9pzhj 1842 2 children child NNS cord-005646-xhx9pzhj 1842 3 admitted admit VBD cord-005646-xhx9pzhj 1842 4 to to IN cord-005646-xhx9pzhj 1842 5 the the DT cord-005646-xhx9pzhj 1842 6 paediatdc paediatdc NNP cord-005646-xhx9pzhj 1842 7 intensive intensive JJ cord-005646-xhx9pzhj 1842 8 care care NN cord-005646-xhx9pzhj 1842 9 unit unit NN cord-005646-xhx9pzhj 1842 10 , , , cord-005646-xhx9pzhj 1842 11 with with IN cord-005646-xhx9pzhj 1842 12 indwelling indwell VBG cord-005646-xhx9pzhj 1842 13 arterial arterial JJ cord-005646-xhx9pzhj 1842 14 and and CC cord-005646-xhx9pzhj 1842 15 central central JJ cord-005646-xhx9pzhj 1842 16 venous venous JJ cord-005646-xhx9pzhj 1842 17 lines line NNS cord-005646-xhx9pzhj 1842 18 as as IN cord-005646-xhx9pzhj 1842 19 part part NN cord-005646-xhx9pzhj 1842 20 of of IN cord-005646-xhx9pzhj 1842 21 their -PRON- PRP$ cord-005646-xhx9pzhj 1842 22 routine routine JJ cord-005646-xhx9pzhj 1842 23 care care NN cord-005646-xhx9pzhj 1842 24 , , , cord-005646-xhx9pzhj 1842 25 were be VBD cord-005646-xhx9pzhj 1842 26 recruited recruit VBN cord-005646-xhx9pzhj 1842 27 for for IN cord-005646-xhx9pzhj 1842 28 the the DT cord-005646-xhx9pzhj 1842 29 study study NN cord-005646-xhx9pzhj 1842 30 . . . cord-005646-xhx9pzhj 1843 1 The the DT cord-005646-xhx9pzhj 1843 2 median median NN cord-005646-xhx9pzhj 1843 3 ( ( -LRB- cord-005646-xhx9pzhj 1843 4 range range NN cord-005646-xhx9pzhj 1843 5 ) ) -RRB- cord-005646-xhx9pzhj 1843 6 age age NN cord-005646-xhx9pzhj 1843 7 was be VBD cord-005646-xhx9pzhj 1843 8 2.0 2.0 CD cord-005646-xhx9pzhj 1843 9 years year NNS cord-005646-xhx9pzhj 1843 10 ( ( -LRB- cord-005646-xhx9pzhj 1843 11 0 0 CD cord-005646-xhx9pzhj 1843 12 - - SYM cord-005646-xhx9pzhj 1843 13 16.6 16.6 CD cord-005646-xhx9pzhj 1843 14 years year NNS cord-005646-xhx9pzhj 1843 15 ) ) -RRB- cord-005646-xhx9pzhj 1843 16 with with IN cord-005646-xhx9pzhj 1843 17 PRISM PRISM NNP cord-005646-xhx9pzhj 1843 18 score score NN cord-005646-xhx9pzhj 1843 19 10 10 CD cord-005646-xhx9pzhj 1843 20 ( ( -LRB- cord-005646-xhx9pzhj 1843 21 0 0 CD cord-005646-xhx9pzhj 1843 22 - - SYM cord-005646-xhx9pzhj 1843 23 36 36 CD cord-005646-xhx9pzhj 1843 24 ) ) -RRB- cord-005646-xhx9pzhj 1843 25 , , , cord-005646-xhx9pzhj 1843 26 Simultaneous Simultaneous NNP cord-005646-xhx9pzhj 1843 27 AKBR AKBR NNP cord-005646-xhx9pzhj 1843 28 and and CC cord-005646-xhx9pzhj 1843 29 VKBR VKBR NNP cord-005646-xhx9pzhj 1843 30 were be VBD cord-005646-xhx9pzhj 1843 31 measured measure VBN cord-005646-xhx9pzhj 1843 32 . . . cord-005646-xhx9pzhj 1844 1 Suppression suppression NN cord-005646-xhx9pzhj 1844 2 of of IN cord-005646-xhx9pzhj 1844 3 ketogenesis ketogenesis NN cord-005646-xhx9pzhj 1844 4 was be VBD cord-005646-xhx9pzhj 1844 5 confirmed confirm VBN cord-005646-xhx9pzhj 1844 6 using use VBG cord-005646-xhx9pzhj 1844 7 a a DT cord-005646-xhx9pzhj 1844 8 rapid rapid JJ cord-005646-xhx9pzhj 1844 9 3-hydroxybutyrate 3-hydroxybutyrate CD cord-005646-xhx9pzhj 1844 10 strip strip NN cord-005646-xhx9pzhj 1844 11 test test NN cord-005646-xhx9pzhj 1844 12 ( ( -LRB- cord-005646-xhx9pzhj 1844 13 Ketofilm Ketofilm NNP cord-005646-xhx9pzhj 1844 14 , , , cord-005646-xhx9pzhj 1844 15 Genzyme Genzyme NNP cord-005646-xhx9pzhj 1844 16 Diagnostics Diagnostics NNPS cord-005646-xhx9pzhj 1844 17 ) ) -RRB- cord-005646-xhx9pzhj 1844 18 pdor pdor NNP cord-005646-xhx9pzhj 1844 19 to to IN cord-005646-xhx9pzhj 1844 20 sampling sampling NN cord-005646-xhx9pzhj 1844 21 . . . cord-005646-xhx9pzhj 1845 1 The the DT cord-005646-xhx9pzhj 1845 2 median median JJ cord-005646-xhx9pzhj 1845 3 VKBR VKBR NNP cord-005646-xhx9pzhj 1845 4 0.50 0.50 CD cord-005646-xhx9pzhj 1845 5 ( ( -LRB- cord-005646-xhx9pzhj 1845 6 range range NN cord-005646-xhx9pzhj 1845 7 0.13 0.13 CD cord-005646-xhx9pzhj 1845 8 - - SYM cord-005646-xhx9pzhj 1845 9 1.46 1.46 CD cord-005646-xhx9pzhj 1845 10 ) ) -RRB- cord-005646-xhx9pzhj 1845 11 was be VBD cord-005646-xhx9pzhj 1845 12 lower low JJR cord-005646-xhx9pzhj 1845 13 than than IN cord-005646-xhx9pzhj 1845 14 median median JJ cord-005646-xhx9pzhj 1845 15 AKBR AKBR NNP cord-005646-xhx9pzhj 1845 16 0.56 0.56 CD cord-005646-xhx9pzhj 1845 17 ( ( -LRB- cord-005646-xhx9pzhj 1845 18 range range NN cord-005646-xhx9pzhj 1845 19 0.11 0.11 CD cord-005646-xhx9pzhj 1845 20 - - HYPH cord-005646-xhx9pzhj 1845 21 1,33 1,33 CD cord-005646-xhx9pzhj 1845 22 ) ) -RRB- cord-005646-xhx9pzhj 1845 23 , , , cord-005646-xhx9pzhj 1845 24 There there EX cord-005646-xhx9pzhj 1845 25 was be VBD cord-005646-xhx9pzhj 1845 26 good good JJ cord-005646-xhx9pzhj 1845 27 agreement agreement NN cord-005646-xhx9pzhj 1845 28 between between IN cord-005646-xhx9pzhj 1845 29 artedal artedal JJ cord-005646-xhx9pzhj 1845 30 and and CC cord-005646-xhx9pzhj 1845 31 venous venous JJ cord-005646-xhx9pzhj 1845 32 ratios ratio NNS cord-005646-xhx9pzhj 1845 33 , , , cord-005646-xhx9pzhj 1845 34 Bland Bland NNP cord-005646-xhx9pzhj 1845 35 - - HYPH cord-005646-xhx9pzhj 1845 36 Altman Altman NNP cord-005646-xhx9pzhj 1845 37 analysis analysis NN cord-005646-xhx9pzhj 1845 38 giving give VBG cord-005646-xhx9pzhj 1845 39 a a DT cord-005646-xhx9pzhj 1845 40 95 95 CD cord-005646-xhx9pzhj 1845 41 % % NN cord-005646-xhx9pzhj 1845 42 confidence confidence NN cord-005646-xhx9pzhj 1845 43 interval interval NN cord-005646-xhx9pzhj 1845 44 for for IN cord-005646-xhx9pzhj 1845 45 relative relative JJ cord-005646-xhx9pzhj 1845 46 bias bias NN cord-005646-xhx9pzhj 1845 47 of of IN cord-005646-xhx9pzhj 1845 48 -0.13 -0.13 CD cord-005646-xhx9pzhj 1845 49 to to IN cord-005646-xhx9pzhj 1845 50 -0.03 -0.03 CD cord-005646-xhx9pzhj 1845 51 . . . cord-005646-xhx9pzhj 1846 1 There there EX cord-005646-xhx9pzhj 1846 2 was be VBD cord-005646-xhx9pzhj 1846 3 a a DT cord-005646-xhx9pzhj 1846 4 significant significant JJ cord-005646-xhx9pzhj 1846 5 correlation correlation NN cord-005646-xhx9pzhj 1846 6 between between IN cord-005646-xhx9pzhj 1846 7 VKBR VKBR NNP cord-005646-xhx9pzhj 1846 8 and and CC cord-005646-xhx9pzhj 1846 9 AKBR AKBR NNP cord-005646-xhx9pzhj 1846 10 r r NN cord-005646-xhx9pzhj 1846 11 2 2 CD cord-005646-xhx9pzhj 1846 12 0,8271 0,8271 CD cord-005646-xhx9pzhj 1846 13 , , , cord-005646-xhx9pzhj 1846 14 p,0.001 p,0.001 NNS cord-005646-xhx9pzhj 1846 15 ( ( -LRB- cord-005646-xhx9pzhj 1846 16 intercept intercept VB cord-005646-xhx9pzhj 1846 17 0.02 0.02 CD cord-005646-xhx9pzhj 1846 18 , , , cord-005646-xhx9pzhj 1846 19 slope slope NN cord-005646-xhx9pzhj 1846 20 0,85 0,85 CD cord-005646-xhx9pzhj 1846 21 ) ) -RRB- cord-005646-xhx9pzhj 1847 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 1847 2 ; ; : cord-005646-xhx9pzhj 1847 3 Values value NNS cord-005646-xhx9pzhj 1847 4 for for IN cord-005646-xhx9pzhj 1847 5 AKBR AKBR NNP cord-005646-xhx9pzhj 1847 6 tend tend VB cord-005646-xhx9pzhj 1847 7 to to TO cord-005646-xhx9pzhj 1847 8 be be VB cord-005646-xhx9pzhj 1847 9 higher high JJR cord-005646-xhx9pzhj 1847 10 than than IN cord-005646-xhx9pzhj 1847 11 VKBR VKBR NNP cord-005646-xhx9pzhj 1847 12 , , , cord-005646-xhx9pzhj 1847 13 however however WRB cord-005646-xhx9pzhj 1847 14 there there EX cord-005646-xhx9pzhj 1847 15 is be VBZ cord-005646-xhx9pzhj 1847 16 a a DT cord-005646-xhx9pzhj 1847 17 consistent consistent JJ cord-005646-xhx9pzhj 1847 18 relationship relationship NN cord-005646-xhx9pzhj 1847 19 in in IN cord-005646-xhx9pzhj 1847 20 critically critically RB cord-005646-xhx9pzhj 1847 21 ill ill JJ cord-005646-xhx9pzhj 1847 22 children child NNS cord-005646-xhx9pzhj 1847 23 . . . cord-005646-xhx9pzhj 1848 1 In in IN cord-005646-xhx9pzhj 1848 2 paediatdc paediatdc NN cord-005646-xhx9pzhj 1848 3 patients patient NNS cord-005646-xhx9pzhj 1848 4 in in IN cord-005646-xhx9pzhj 1848 5 whom whom WP cord-005646-xhx9pzhj 1848 6 ketogenesis ketogenesis NN cord-005646-xhx9pzhj 1848 7 is be VBZ cord-005646-xhx9pzhj 1848 8 suppressed suppress VBN cord-005646-xhx9pzhj 1848 9 , , , cord-005646-xhx9pzhj 1848 10 VKBR VKBR NNP cord-005646-xhx9pzhj 1848 11 may may MD cord-005646-xhx9pzhj 1848 12 be be VB cord-005646-xhx9pzhj 1848 13 considered consider VBN cord-005646-xhx9pzhj 1848 14 equivalent equivalent JJ cord-005646-xhx9pzhj 1848 15 to to IN cord-005646-xhx9pzhj 1848 16 AKBR AKBR NNP cord-005646-xhx9pzhj 1848 17 . . . cord-005646-xhx9pzhj 1849 1 This this DT cord-005646-xhx9pzhj 1849 2 simple simple JJ cord-005646-xhx9pzhj 1849 3 test test NN cord-005646-xhx9pzhj 1849 4 may may MD cord-005646-xhx9pzhj 1849 5 prove prove VB cord-005646-xhx9pzhj 1849 6 to to TO cord-005646-xhx9pzhj 1849 7 be be VB cord-005646-xhx9pzhj 1849 8 a a DT cord-005646-xhx9pzhj 1849 9 useful useful JJ cord-005646-xhx9pzhj 1849 10 adjunct adjunct NN cord-005646-xhx9pzhj 1849 11 in in IN cord-005646-xhx9pzhj 1849 12 predicting predict VBG cord-005646-xhx9pzhj 1849 13 mortality mortality NN cord-005646-xhx9pzhj 1849 14 in in IN cord-005646-xhx9pzhj 1849 15 cdt{cally cdt{cally RB cord-005646-xhx9pzhj 1849 16 ill ill JJ cord-005646-xhx9pzhj 1849 17 children child NNS cord-005646-xhx9pzhj 1849 18 . . . cord-005646-xhx9pzhj 1850 1 To to TO cord-005646-xhx9pzhj 1850 2 understand understand VB cord-005646-xhx9pzhj 1850 3 the the DT cord-005646-xhx9pzhj 1850 4 present present JJ cord-005646-xhx9pzhj 1850 5 status status NN cord-005646-xhx9pzhj 1850 6 of of IN cord-005646-xhx9pzhj 1850 7 pediatric pediatric JJ cord-005646-xhx9pzhj 1850 8 intensive intensive JJ cord-005646-xhx9pzhj 1850 9 care care NN cord-005646-xhx9pzhj 1850 10 in in IN cord-005646-xhx9pzhj 1850 11 China China NNP cord-005646-xhx9pzhj 1850 12 , , , cord-005646-xhx9pzhj 1850 13 we -PRON- PRP cord-005646-xhx9pzhj 1850 14 conducted conduct VBD cord-005646-xhx9pzhj 1850 15 a a DT cord-005646-xhx9pzhj 1850 16 survey survey NN cord-005646-xhx9pzhj 1850 17 between between IN cord-005646-xhx9pzhj 1850 18 October October NNP cord-005646-xhx9pzhj 1850 19 and and CC cord-005646-xhx9pzhj 1850 20 December December NNP cord-005646-xhx9pzhj 1850 21 , , , cord-005646-xhx9pzhj 1850 22 1993 1993 CD cord-005646-xhx9pzhj 1850 23 , , , cord-005646-xhx9pzhj 1850 24 involving involve VBG cord-005646-xhx9pzhj 1850 25 20 20 CD cord-005646-xhx9pzhj 1850 26 hospitals hospital NNS cord-005646-xhx9pzhj 1850 27 in in IN cord-005646-xhx9pzhj 1850 28 14 14 CD cord-005646-xhx9pzhj 1850 29 provinces province NNS cord-005646-xhx9pzhj 1850 30 and and CC cord-005646-xhx9pzhj 1850 31 municipalities municipality NNS cord-005646-xhx9pzhj 1850 32 . . . cord-005646-xhx9pzhj 1851 1 The the DT cord-005646-xhx9pzhj 1851 2 results result NNS cord-005646-xhx9pzhj 1851 3 showed show VBD cord-005646-xhx9pzhj 1851 4 that that IN cord-005646-xhx9pzhj 1851 5 there there EX cord-005646-xhx9pzhj 1851 6 were be VBD cord-005646-xhx9pzhj 1851 7 totally totally RB cord-005646-xhx9pzhj 1851 8 41 41 CD cord-005646-xhx9pzhj 1851 9 ICUs icu NNS cord-005646-xhx9pzhj 1851 10 for for IN cord-005646-xhx9pzhj 1851 11 pediatric pediatric JJ cord-005646-xhx9pzhj 1851 12 patients patient NNS cord-005646-xhx9pzhj 1851 13 , , , cord-005646-xhx9pzhj 1851 14 including include VBG cord-005646-xhx9pzhj 1851 15 19 19 CD cord-005646-xhx9pzhj 1851 16 pediatric pediatric JJ cord-005646-xhx9pzhj 1851 17 ICUs icu NNS cord-005646-xhx9pzhj 1851 18 ( ( -LRB- cord-005646-xhx9pzhj 1851 19 PICU PICU NNP cord-005646-xhx9pzhj 1851 20 ) ) -RRB- cord-005646-xhx9pzhj 1851 21 , , , cord-005646-xhx9pzhj 1851 22 18 18 CD cord-005646-xhx9pzhj 1851 23 neonatal neonatal JJ cord-005646-xhx9pzhj 1851 24 ICUs icu NNS cord-005646-xhx9pzhj 1851 25 ( ( -LRB- cord-005646-xhx9pzhj 1851 26 NICU NICU NNP cord-005646-xhx9pzhj 1851 27 ) ) -RRB- cord-005646-xhx9pzhj 1851 28 and and CC cord-005646-xhx9pzhj 1851 29 4 4 CD cord-005646-xhx9pzhj 1851 30 pediatric pediatric JJ cord-005646-xhx9pzhj 1851 31 surgical surgical JJ cord-005646-xhx9pzhj 1851 32 ICUs icus NN cord-005646-xhx9pzhj 1851 33 ( ( -LRB- cord-005646-xhx9pzhj 1851 34 SICU SICU NNP cord-005646-xhx9pzhj 1851 35 ) ) -RRB- cord-005646-xhx9pzhj 1851 36 , , , cord-005646-xhx9pzhj 1851 37 with with IN cord-005646-xhx9pzhj 1851 38 total total NN cord-005646-xhx9pzhj 1851 39 of of IN cord-005646-xhx9pzhj 1851 40 403 403 CD cord-005646-xhx9pzhj 1851 41 beds bed NNS cord-005646-xhx9pzhj 1851 42 . . . cord-005646-xhx9pzhj 1852 1 The the DT cord-005646-xhx9pzhj 1852 2 physicians physician NNS cord-005646-xhx9pzhj 1852 3 to to IN cord-005646-xhx9pzhj 1852 4 bed bed NN cord-005646-xhx9pzhj 1852 5 and and CC cord-005646-xhx9pzhj 1852 6 nurses nurse NNS cord-005646-xhx9pzhj 1852 7 to to IN cord-005646-xhx9pzhj 1852 8 bed bed NN cord-005646-xhx9pzhj 1852 9 ratios ratio NNS cord-005646-xhx9pzhj 1852 10 were be VBD cord-005646-xhx9pzhj 1852 11 1:1.5 1:1.5 CD cord-005646-xhx9pzhj 1852 12 and and CC cord-005646-xhx9pzhj 1852 13 1:0.91 1:0.91 CC cord-005646-xhx9pzhj 1852 14 respectively respectively RB cord-005646-xhx9pzhj 1852 15 . . . cord-005646-xhx9pzhj 1853 1 The the DT cord-005646-xhx9pzhj 1853 2 average average JJ cord-005646-xhx9pzhj 1853 3 number number NN cord-005646-xhx9pzhj 1853 4 of of IN cord-005646-xhx9pzhj 1853 5 equipment equipment NN cord-005646-xhx9pzhj 1853 6 per per IN cord-005646-xhx9pzhj 1853 7 bed bed NN cord-005646-xhx9pzhj 1853 8 was be VBD cord-005646-xhx9pzhj 1853 9 0.47 0.47 CD cord-005646-xhx9pzhj 1853 10 ventilator ventilator NN cord-005646-xhx9pzhj 1853 11 , , , cord-005646-xhx9pzhj 1853 12 0.34 0.34 CD cord-005646-xhx9pzhj 1853 13 multi multi JJ cord-005646-xhx9pzhj 1853 14 - - JJ cord-005646-xhx9pzhj 1853 15 fnnction fnnction JJ cord-005646-xhx9pzhj 1853 16 monitor monitor NN cord-005646-xhx9pzhj 1853 17 and and CC cord-005646-xhx9pzhj 1853 18 0.47 0.47 CD cord-005646-xhx9pzhj 1853 19 infusion infusion NN cord-005646-xhx9pzhj 1853 20 pump pump NN cord-005646-xhx9pzhj 1853 21 . . . cord-005646-xhx9pzhj 1854 1 Very very RB cord-005646-xhx9pzhj 1854 2 few few JJ cord-005646-xhx9pzhj 1854 3 of of IN cord-005646-xhx9pzhj 1854 4 the the DT cord-005646-xhx9pzhj 1854 5 ICUs icu NNS cord-005646-xhx9pzhj 1854 6 had have VBD cord-005646-xhx9pzhj 1854 7 portable portable JJ cord-005646-xhx9pzhj 1854 8 X x NN cord-005646-xhx9pzhj 1854 9 - - NN cord-005646-xhx9pzhj 1854 10 ray ray NN cord-005646-xhx9pzhj 1854 11 machine machine NN cord-005646-xhx9pzhj 1854 12 , , , cord-005646-xhx9pzhj 1854 13 biochemical biochemical JJ cord-005646-xhx9pzhj 1854 14 and and CC cord-005646-xhx9pzhj 1854 15 blood blood NN cord-005646-xhx9pzhj 1854 16 gas gas NN cord-005646-xhx9pzhj 1854 17 analyzers analyzer NNS cord-005646-xhx9pzhj 1854 18 , , , cord-005646-xhx9pzhj 1854 19 and and CC cord-005646-xhx9pzhj 1854 20 hemodialysis hemodialysis NN cord-005646-xhx9pzhj 1854 21 machines machine NNS cord-005646-xhx9pzhj 1854 22 . . . cord-005646-xhx9pzhj 1855 1 The the DT cord-005646-xhx9pzhj 1855 2 most most RBS cord-005646-xhx9pzhj 1855 3 frequently frequently RB cord-005646-xhx9pzhj 1855 4 treated treat VBN cord-005646-xhx9pzhj 1855 5 diseases disease NNS cord-005646-xhx9pzhj 1855 6 / / SYM cord-005646-xhx9pzhj 1855 7 conditions condition NNS cord-005646-xhx9pzhj 1855 8 were be VBD cord-005646-xhx9pzhj 1855 9 pneumonia pneumonia NN cord-005646-xhx9pzhj 1855 10 , , , cord-005646-xhx9pzhj 1855 11 intracraniat intracraniat NNP cord-005646-xhx9pzhj 1855 12 infections infection NNS cord-005646-xhx9pzhj 1855 13 , , , cord-005646-xhx9pzhj 1855 14 post post NN cord-005646-xhx9pzhj 1855 15 - - JJ cord-005646-xhx9pzhj 1855 16 operation operation NN cord-005646-xhx9pzhj 1855 17 and and CC cord-005646-xhx9pzhj 1855 18 sepsis sepsis NN cord-005646-xhx9pzhj 1855 19 in in IN cord-005646-xhx9pzhj 1855 20 PICUs picu NNS cord-005646-xhx9pzhj 1855 21 , , , cord-005646-xhx9pzhj 1855 22 and and CC cord-005646-xhx9pzhj 1855 23 neonatal neonatal JJ cord-005646-xhx9pzhj 1855 24 pneumonia pneumonia NN cord-005646-xhx9pzhj 1855 25 , , , cord-005646-xhx9pzhj 1855 26 hypoxic hypoxic JJ cord-005646-xhx9pzhj 1855 27 ischemic ischemic JJ cord-005646-xhx9pzhj 1855 28 encephalopathy encephalopathy NN cord-005646-xhx9pzhj 1855 29 and and CC cord-005646-xhx9pzhj 1855 30 sclerema sclerema NN cord-005646-xhx9pzhj 1855 31 in in IN cord-005646-xhx9pzhj 1855 32 NICUs NICUs NNP cord-005646-xhx9pzhj 1855 33 . . . cord-005646-xhx9pzhj 1856 1 Pneumonia pneumonia NN cord-005646-xhx9pzhj 1856 2 and and CC cord-005646-xhx9pzhj 1856 3 respiratory respiratory JJ cord-005646-xhx9pzhj 1856 4 failure failure NN cord-005646-xhx9pzhj 1856 5 accounted account VBD cord-005646-xhx9pzhj 1856 6 for for IN cord-005646-xhx9pzhj 1856 7 33.29 33.29 CD cord-005646-xhx9pzhj 1856 8 % % NN cord-005646-xhx9pzhj 1856 9 and and CC cord-005646-xhx9pzhj 1856 10 26.50 26.50 CD cord-005646-xhx9pzhj 1856 11 % % NN cord-005646-xhx9pzhj 1856 12 of of IN cord-005646-xhx9pzhj 1856 13 all all PDT cord-005646-xhx9pzhj 1856 14 the the DT cord-005646-xhx9pzhj 1856 15 diseases disease NNS cord-005646-xhx9pzhj 1856 16 / / SYM cord-005646-xhx9pzhj 1856 17 conditions condition NNS cord-005646-xhx9pzhj 1856 18 treated treat VBN cord-005646-xhx9pzhj 1856 19 in in IN cord-005646-xhx9pzhj 1856 20 the the DT cord-005646-xhx9pzhj 1856 21 ICUs ICUs NNP cord-005646-xhx9pzhj 1856 22 and and CC cord-005646-xhx9pzhj 1856 23 the the DT cord-005646-xhx9pzhj 1856 24 mean mean JJ cord-005646-xhx9pzhj 1856 25 case case NN cord-005646-xhx9pzhj 1856 26 fatality fatality NN cord-005646-xhx9pzhj 1856 27 rate rate NN cord-005646-xhx9pzhj 1856 28 of of IN cord-005646-xhx9pzhj 1856 29 respiratory respiratory JJ cord-005646-xhx9pzhj 1856 30 failure failure NN cord-005646-xhx9pzhj 1856 31 was be VBD cord-005646-xhx9pzhj 1856 32 24.50 24.50 CD cord-005646-xhx9pzhj 1856 33 % % NN cord-005646-xhx9pzhj 1856 34 . . . cord-005646-xhx9pzhj 1857 1 The the DT cord-005646-xhx9pzhj 1857 2 results result NNS cord-005646-xhx9pzhj 1857 3 of of IN cord-005646-xhx9pzhj 1857 4 the the DT cord-005646-xhx9pzhj 1857 5 survey survey NN cord-005646-xhx9pzhj 1857 6 suggest suggest VBP cord-005646-xhx9pzhj 1857 7 that that IN cord-005646-xhx9pzhj 1857 8 there there EX cord-005646-xhx9pzhj 1857 9 is be VBZ cord-005646-xhx9pzhj 1857 10 shortage shortage NN cord-005646-xhx9pzhj 1857 11 of of IN cord-005646-xhx9pzhj 1857 12 tCU tcu IN cord-005646-xhx9pzhj 1857 13 beds bed NNS cord-005646-xhx9pzhj 1857 14 and and CC cord-005646-xhx9pzhj 1857 15 modern modern JJ cord-005646-xhx9pzhj 1857 16 equipment equipment NN cord-005646-xhx9pzhj 1857 17 , , , cord-005646-xhx9pzhj 1857 18 and and CC cord-005646-xhx9pzhj 1857 19 treatment treatment NN cord-005646-xhx9pzhj 1857 20 is be VBZ cord-005646-xhx9pzhj 1857 21 often often RB cord-005646-xhx9pzhj 1857 22 delayed delay VBN cord-005646-xhx9pzhj 1857 23 due due IN cord-005646-xhx9pzhj 1857 24 to to IN cord-005646-xhx9pzhj 1857 25 excessively excessively RB cord-005646-xhx9pzhj 1857 26 strict strict JJ cord-005646-xhx9pzhj 1857 27 criteria criterion NNS cord-005646-xhx9pzhj 1857 28 for for IN cord-005646-xhx9pzhj 1857 29 mechanical mechanical JJ cord-005646-xhx9pzhj 1857 30 ventilation ventilation NN cord-005646-xhx9pzhj 1857 31 . . . cord-005646-xhx9pzhj 1858 1 A a DT cord-005646-xhx9pzhj 1858 2 set set NN cord-005646-xhx9pzhj 1858 3 of of IN cord-005646-xhx9pzhj 1858 4 simple simple JJ cord-005646-xhx9pzhj 1858 5 , , , cord-005646-xhx9pzhj 1858 6 and and CC cord-005646-xhx9pzhj 1858 7 nationally nationally RB cord-005646-xhx9pzhj 1858 8 acceptable acceptable JJ cord-005646-xhx9pzhj 1858 9 criteria criterion NNS cord-005646-xhx9pzhj 1858 10 for for IN cord-005646-xhx9pzhj 1858 11 evaluation evaluation NN cord-005646-xhx9pzhj 1858 12 of of IN cord-005646-xhx9pzhj 1858 13 severity severity NN cord-005646-xhx9pzhj 1858 14 and and CC cord-005646-xhx9pzhj 1858 15 cure cure NN cord-005646-xhx9pzhj 1858 16 of of IN cord-005646-xhx9pzhj 1858 17 the the DT cord-005646-xhx9pzhj 1858 18 diseases disease NNS cord-005646-xhx9pzhj 1858 19 / / SYM cord-005646-xhx9pzhj 1858 20 conditions condition NNS cord-005646-xhx9pzhj 1858 21 is be VBZ cord-005646-xhx9pzhj 1858 22 urgently urgently RB cord-005646-xhx9pzhj 1858 23 required require VBN cord-005646-xhx9pzhj 1858 24 . . . cord-005646-xhx9pzhj 1859 1 The the DT cord-005646-xhx9pzhj 1859 2 medical medical JJ cord-005646-xhx9pzhj 1859 3 reports report NNS cord-005646-xhx9pzhj 1859 4 of of IN cord-005646-xhx9pzhj 1859 5 286 286 CD cord-005646-xhx9pzhj 1859 6 children child NNS cord-005646-xhx9pzhj 1859 7 were be VBD cord-005646-xhx9pzhj 1859 8 reviewed review VBN cord-005646-xhx9pzhj 1859 9 and and CC cord-005646-xhx9pzhj 1859 10 each each DT cord-005646-xhx9pzhj 1859 11 admission admission NN cord-005646-xhx9pzhj 1859 12 was be VBD cord-005646-xhx9pzhj 1859 13 analysed analyse VBN cord-005646-xhx9pzhj 1859 14 in in IN cord-005646-xhx9pzhj 1859 15 terms term NNS cord-005646-xhx9pzhj 1859 16 of of IN cord-005646-xhx9pzhj 1859 17 age age NN cord-005646-xhx9pzhj 1859 18 , , , cord-005646-xhx9pzhj 1859 19 sex sex NN cord-005646-xhx9pzhj 1859 20 , , , cord-005646-xhx9pzhj 1859 21 diagnosis diagnosis NN cord-005646-xhx9pzhj 1859 22 , , , cord-005646-xhx9pzhj 1859 23 management management NN cord-005646-xhx9pzhj 1859 24 within within IN cord-005646-xhx9pzhj 1859 25 the the DT cord-005646-xhx9pzhj 1859 26 hosp hosp NNP cord-005646-xhx9pzhj 1859 27 ~ ~ NFP cord-005646-xhx9pzhj 1859 28 al al NNP cord-005646-xhx9pzhj 1859 29 , , , cord-005646-xhx9pzhj 1859 30 length length NN cord-005646-xhx9pzhj 1859 31 of of IN cord-005646-xhx9pzhj 1859 32 hospital hospital NN cord-005646-xhx9pzhj 1859 33 stay stay NN cord-005646-xhx9pzhj 1859 34 and and CC cord-005646-xhx9pzhj 1859 35 type type NN cord-005646-xhx9pzhj 1859 36 of of IN cord-005646-xhx9pzhj 1859 37 poisoning poisoning NN cord-005646-xhx9pzhj 1859 38 . . . cord-005646-xhx9pzhj 1860 1 The the DT cord-005646-xhx9pzhj 1860 2 youngest young JJS cord-005646-xhx9pzhj 1860 3 age age NN cord-005646-xhx9pzhj 1860 4 was be VBD cord-005646-xhx9pzhj 1860 5 23 23 CD cord-005646-xhx9pzhj 1860 6 days day NNS cord-005646-xhx9pzhj 1860 7 and and CC cord-005646-xhx9pzhj 1860 8 the the DT cord-005646-xhx9pzhj 1860 9 oldest old JJS cord-005646-xhx9pzhj 1860 10 was be VBD cord-005646-xhx9pzhj 1860 11 16 16 CD cord-005646-xhx9pzhj 1860 12 years year NNS cord-005646-xhx9pzhj 1860 13 . . . cord-005646-xhx9pzhj 1861 1 Hundred hundred CD cord-005646-xhx9pzhj 1861 2 and and CC cord-005646-xhx9pzhj 1861 3 twelve twelve CD cord-005646-xhx9pzhj 1861 4 ( ( -LRB- cord-005646-xhx9pzhj 1861 5 39.5 39.5 CD cord-005646-xhx9pzhj 1861 6 % % NN cord-005646-xhx9pzhj 1861 7 ) ) -RRB- cord-005646-xhx9pzhj 1861 8 of of IN cord-005646-xhx9pzhj 1861 9 the the DT cord-005646-xhx9pzhj 1861 10 children child NNS cord-005646-xhx9pzhj 1861 11 were be VBD cord-005646-xhx9pzhj 1861 12 girls girl NNS cord-005646-xhx9pzhj 1861 13 and and CC cord-005646-xhx9pzhj 1861 14 174 174 CD cord-005646-xhx9pzhj 1861 15 ( ( -LRB- cord-005646-xhx9pzhj 1861 16 60.5 60.5 CD cord-005646-xhx9pzhj 1861 17 % % NN cord-005646-xhx9pzhj 1861 18 ) ) -RRB- cord-005646-xhx9pzhj 1861 19 were be VBD cord-005646-xhx9pzhj 1861 20 boys boy NNS cord-005646-xhx9pzhj 1861 21 . . . cord-005646-xhx9pzhj 1862 1 The the DT cord-005646-xhx9pzhj 1862 2 most most RBS cord-005646-xhx9pzhj 1862 3 common common JJ cord-005646-xhx9pzhj 1862 4 ( ( -LRB- cord-005646-xhx9pzhj 1862 5 26.5 26.5 CD cord-005646-xhx9pzhj 1862 6 % % NN cord-005646-xhx9pzhj 1862 7 ) ) -RRB- cord-005646-xhx9pzhj 1862 8 reason reason NN cord-005646-xhx9pzhj 1862 9 of of IN cord-005646-xhx9pzhj 1862 10 admission admission NN cord-005646-xhx9pzhj 1862 11 was be VBD cord-005646-xhx9pzhj 1862 12 intoxication intoxication NN cord-005646-xhx9pzhj 1862 13 among among IN cord-005646-xhx9pzhj 1862 14 all all DT cord-005646-xhx9pzhj 1862 15 of of IN cord-005646-xhx9pzhj 1862 16 the the DT cord-005646-xhx9pzhj 1862 17 cases case NNS cord-005646-xhx9pzhj 1862 18 and and CC cord-005646-xhx9pzhj 1862 19 the the DT cord-005646-xhx9pzhj 1862 20 greatest great JJS cord-005646-xhx9pzhj 1862 21 group group NN cord-005646-xhx9pzhj 1862 22 ( ( -LRB- cord-005646-xhx9pzhj 1862 23 73.7 73.7 CD cord-005646-xhx9pzhj 1862 24 % % NN cord-005646-xhx9pzhj 1862 25 ) ) -RRB- cord-005646-xhx9pzhj 1862 26 of of IN cord-005646-xhx9pzhj 1862 27 the the DT cord-005646-xhx9pzhj 1862 28 poisoned poison VBN cord-005646-xhx9pzhj 1862 29 children child NNS cord-005646-xhx9pzhj 1862 30 had have VBD cord-005646-xhx9pzhj 1862 31 ingested ingest VBN cord-005646-xhx9pzhj 1862 32 medication medication NN cord-005646-xhx9pzhj 1862 33 which which WDT cord-005646-xhx9pzhj 1862 34 was be VBD cord-005646-xhx9pzhj 1862 35 followed follow VBN cord-005646-xhx9pzhj 1862 36 by by IN cord-005646-xhx9pzhj 1862 37 another another DT cord-005646-xhx9pzhj 1862 38 group group NN cord-005646-xhx9pzhj 1862 39 of of IN cord-005646-xhx9pzhj 1862 40 patients patient NNS cord-005646-xhx9pzhj 1862 41 ( ( -LRB- cord-005646-xhx9pzhj 1862 42 9.2 9.2 CD cord-005646-xhx9pzhj 1862 43 % % NN cord-005646-xhx9pzhj 1862 44 ) ) -RRB- cord-005646-xhx9pzhj 1862 45 who who WP cord-005646-xhx9pzhj 1862 46 had have VBD cord-005646-xhx9pzhj 1862 47 eaten eat VBN cord-005646-xhx9pzhj 1862 48 mushrooms mushroom NNS cord-005646-xhx9pzhj 1862 49 . . . cord-005646-xhx9pzhj 1863 1 The the DT cord-005646-xhx9pzhj 1863 2 peak peak NN cord-005646-xhx9pzhj 1863 3 incidence incidence NN cord-005646-xhx9pzhj 1863 4 of of IN cord-005646-xhx9pzhj 1863 5 drug drug NN cord-005646-xhx9pzhj 1863 6 ingestion ingestion NN cord-005646-xhx9pzhj 1863 7 was be VBD cord-005646-xhx9pzhj 1863 8 salicylate salicylate NN cord-005646-xhx9pzhj 1863 9 intoxication intoxication NN cord-005646-xhx9pzhj 1863 10 ( ( -LRB- cord-005646-xhx9pzhj 1863 11 20 20 CD cord-005646-xhx9pzhj 1863 12 % % NN cord-005646-xhx9pzhj 1863 13 ) ) -RRB- cord-005646-xhx9pzhj 1863 14 . . . cord-005646-xhx9pzhj 1864 1 Forty forty CD cord-005646-xhx9pzhj 1864 2 drug drug NN cord-005646-xhx9pzhj 1864 3 poisoninigs poisoninig NNS cord-005646-xhx9pzhj 1864 4 were be VBD cord-005646-xhx9pzhj 1864 5 accidental accidental JJ cord-005646-xhx9pzhj 1864 6 while while IN cord-005646-xhx9pzhj 1864 7 16 16 CD cord-005646-xhx9pzhj 1864 8 was be VBD cord-005646-xhx9pzhj 1864 9 intentional intentional JJ cord-005646-xhx9pzhj 1864 10 . . . cord-005646-xhx9pzhj 1865 1 The the DT cord-005646-xhx9pzhj 1865 2 majority majority NN cord-005646-xhx9pzhj 1865 3 ( ( -LRB- cord-005646-xhx9pzhj 1865 4 82.4 82.4 CD cord-005646-xhx9pzhj 1865 5 % % NN cord-005646-xhx9pzhj 1865 6 ) ) -RRB- cord-005646-xhx9pzhj 1865 7 of of IN cord-005646-xhx9pzhj 1865 8 the the DT cord-005646-xhx9pzhj 1865 9 cases case NNS cord-005646-xhx9pzhj 1865 10 that that WDT cord-005646-xhx9pzhj 1865 11 committed committed JJ cord-005646-xhx9pzhj 1865 12 suicide suicide NN cord-005646-xhx9pzhj 1865 13 was be VBD cord-005646-xhx9pzhj 1865 14 between between IN cord-005646-xhx9pzhj 1865 15 12 12 CD cord-005646-xhx9pzhj 1865 16 and and CC cord-005646-xhx9pzhj 1865 17 t7 t7 NNP cord-005646-xhx9pzhj 1865 18 years year NNS cord-005646-xhx9pzhj 1865 19 old old JJ cord-005646-xhx9pzhj 1865 20 , , , cord-005646-xhx9pzhj 1865 21 and and CC cord-005646-xhx9pzhj 1865 22 the the DT cord-005646-xhx9pzhj 1865 23 main main JJ cord-005646-xhx9pzhj 1865 24 cause cause NN cord-005646-xhx9pzhj 1865 25 of of IN cord-005646-xhx9pzhj 1865 26 suicide suicide NN cord-005646-xhx9pzhj 1865 27 was be VBD cord-005646-xhx9pzhj 1865 28 being be VBG cord-005646-xhx9pzhj 1865 29 unsuccessful unsuccessful JJ cord-005646-xhx9pzhj 1865 30 at at IN cord-005646-xhx9pzhj 1865 31 school school NN cord-005646-xhx9pzhj 1865 32 . . . cord-005646-xhx9pzhj 1866 1 We -PRON- PRP cord-005646-xhx9pzhj 1866 2 conclude conclude VBP cord-005646-xhx9pzhj 1866 3 that that IN cord-005646-xhx9pzhj 1866 4 poisoning poisoning NN cord-005646-xhx9pzhj 1866 5 -especially -especially HYPH cord-005646-xhx9pzhj 1866 6 salicylate salicylate NN cord-005646-xhx9pzhj 1866 7 intoxication intoxication NN cord-005646-xhx9pzhj 1866 8 -is -is : cord-005646-xhx9pzhj 1866 9 still still RB cord-005646-xhx9pzhj 1866 10 a a DT cord-005646-xhx9pzhj 1866 11 major major JJ cord-005646-xhx9pzhj 1866 12 problem problem NN cord-005646-xhx9pzhj 1866 13 in in IN cord-005646-xhx9pzhj 1866 14 Turkey Turkey NNP cord-005646-xhx9pzhj 1867 1 and and CC cord-005646-xhx9pzhj 1867 2 we -PRON- PRP cord-005646-xhx9pzhj 1867 3 believe believe VBP cord-005646-xhx9pzhj 1867 4 that that IN cord-005646-xhx9pzhj 1867 5 emphasis emphasis NN cord-005646-xhx9pzhj 1867 6 on on IN cord-005646-xhx9pzhj 1867 7 the the DT cord-005646-xhx9pzhj 1867 8 need need NN cord-005646-xhx9pzhj 1867 9 to to TO cord-005646-xhx9pzhj 1867 10 stere stere VB cord-005646-xhx9pzhj 1867 11 all all DT cord-005646-xhx9pzhj 1867 12 kinds kind NNS cord-005646-xhx9pzhj 1867 13 of of IN cord-005646-xhx9pzhj 1867 14 drugs drug NNS cord-005646-xhx9pzhj 1867 15 in in IN cord-005646-xhx9pzhj 1867 16 a a DT cord-005646-xhx9pzhj 1867 17 secure secure JJ cord-005646-xhx9pzhj 1867 18 place place NN cord-005646-xhx9pzhj 1867 19 and and CC cord-005646-xhx9pzhj 1867 20 re re NN cord-005646-xhx9pzhj 1867 21 - - NN cord-005646-xhx9pzhj 1867 22 examination examination NN cord-005646-xhx9pzhj 1867 23 of of IN cord-005646-xhx9pzhj 1867 24 a a DT cord-005646-xhx9pzhj 1867 25 chin chin NN cord-005646-xhx9pzhj 1867 26 resistant resistant JJ cord-005646-xhx9pzhj 1867 27 packaging packaging NN cord-005646-xhx9pzhj 1867 28 should should MD cord-005646-xhx9pzhj 1867 29 help help VB cord-005646-xhx9pzhj 1867 30 to to TO cord-005646-xhx9pzhj 1867 31 reduce reduce VB cord-005646-xhx9pzhj 1867 32 childhood childhood NN cord-005646-xhx9pzhj 1867 33 poisoning poisoning NN cord-005646-xhx9pzhj 1867 34 significantly significantly RB cord-005646-xhx9pzhj 1867 35 which which WDT cord-005646-xhx9pzhj 1867 36 is be VBZ cord-005646-xhx9pzhj 1867 37 a a DT cord-005646-xhx9pzhj 1867 38 preventable preventable JJ cord-005646-xhx9pzhj 1867 39 condition condition NN cord-005646-xhx9pzhj 1867 40 . . . cord-005646-xhx9pzhj 1868 1 Included include VBN cord-005646-xhx9pzhj 1868 2 were be VBD cord-005646-xhx9pzhj 1868 3 all all DT cord-005646-xhx9pzhj 1868 4 patients patient NNS cord-005646-xhx9pzhj 1868 5 who who WP cord-005646-xhx9pzhj 1868 6 died die VBD cord-005646-xhx9pzhj 1868 7 in in IN cord-005646-xhx9pzhj 1868 8 the the DT cord-005646-xhx9pzhj 1868 9 hospital hospital NN cord-005646-xhx9pzhj 1868 10 , , , cord-005646-xhx9pzhj 1868 11 except except IN cord-005646-xhx9pzhj 1868 12 those those DT cord-005646-xhx9pzhj 1868 13 treated treat VBN cord-005646-xhx9pzhj 1868 14 in in IN cord-005646-xhx9pzhj 1868 15 the the DT cord-005646-xhx9pzhj 1868 16 neonatal neonatal JJ cord-005646-xhx9pzhj 1868 17 ICU ICU NNP cord-005646-xhx9pzhj 1868 18 ( ( -LRB- cord-005646-xhx9pzhj 1868 19 predominantly predominantly RB cord-005646-xhx9pzhj 1868 20 premature premature JJ cord-005646-xhx9pzhj 1868 21 and and CC cord-005646-xhx9pzhj 1868 22 SGA SGA NNP cord-005646-xhx9pzhj 1868 23 newborns newborn NNS cord-005646-xhx9pzhj 1868 24 ) ) -RRB- cord-005646-xhx9pzhj 1868 25 and and CC cord-005646-xhx9pzhj 1868 26 those those DT cord-005646-xhx9pzhj 1868 27 who who WP cord-005646-xhx9pzhj 1868 28 died die VBD cord-005646-xhx9pzhj 1868 29 in in IN cord-005646-xhx9pzhj 1868 30 the the DT cord-005646-xhx9pzhj 1868 31 emergency emergency NN cord-005646-xhx9pzhj 1868 32 room room NN cord-005646-xhx9pzhj 1868 33 . . . cord-005646-xhx9pzhj 1869 1 Among among IN cord-005646-xhx9pzhj 1869 2 a a DT cord-005646-xhx9pzhj 1869 3 total total NN cord-005646-xhx9pzhj 1869 4 of of IN cord-005646-xhx9pzhj 1869 5 7179 7179 CD cord-005646-xhx9pzhj 1869 6 hospital hospital NN cord-005646-xhx9pzhj 1869 7 admissions admission NNS cord-005646-xhx9pzhj 1869 8 ( ( -LRB- cord-005646-xhx9pzhj 1869 9 excluding exclude VBG cord-005646-xhx9pzhj 1869 10 the the DT cord-005646-xhx9pzhj 1869 11 neonatal neonatal JJ cord-005646-xhx9pzhj 1869 12 ICU ICU NNP cord-005646-xhx9pzhj 1869 13 and and CC cord-005646-xhx9pzhj 1869 14 emergency emergency NN cord-005646-xhx9pzhj 1869 15 room room NN cord-005646-xhx9pzhj 1869 16 ) ) -RRB- cord-005646-xhx9pzhj 1869 17 , , , cord-005646-xhx9pzhj 1869 18 99 99 CD cord-005646-xhx9pzhj 1869 19 patients patient NNS cord-005646-xhx9pzhj 1869 20 died die VBD cord-005646-xhx9pzhj 1869 21 ( ( -LRB- cord-005646-xhx9pzhj 1869 22 1.4 1.4 CD cord-005646-xhx9pzhj 1869 23 % % NN cord-005646-xhx9pzhj 1869 24 ) ) -RRB- cord-005646-xhx9pzhj 1869 25 . . . cord-005646-xhx9pzhj 1870 1 Of of IN cord-005646-xhx9pzhj 1870 2 these these DT cord-005646-xhx9pzhj 1870 3 99 99 CD cord-005646-xhx9pzhj 1870 4 patients patient NNS cord-005646-xhx9pzhj 1870 5 73 73 CD cord-005646-xhx9pzhj 1870 6 ( ( -LRB- cord-005646-xhx9pzhj 1870 7 74 74 CD cord-005646-xhx9pzhj 1870 8 % % NN cord-005646-xhx9pzhj 1870 9 ) ) -RRB- cord-005646-xhx9pzhj 1870 10 died die VBD cord-005646-xhx9pzhj 1870 11 in in IN cord-005646-xhx9pzhj 1870 12 the the DT cord-005646-xhx9pzhj 1870 13 pediatric pediatric JJ cord-005646-xhx9pzhj 1870 14 ICU ICU NNP cord-005646-xhx9pzhj 1870 15 , , , cord-005646-xhx9pzhj 1870 16 18 18 CD cord-005646-xhx9pzhj 1870 17 ( ( -LRB- cord-005646-xhx9pzhj 1870 18 18 18 CD cord-005646-xhx9pzhj 1870 19 % % NN cord-005646-xhx9pzhj 1870 20 ) ) -RRB- cord-005646-xhx9pzhj 1870 21 in in IN cord-005646-xhx9pzhj 1870 22 the the DT cord-005646-xhx9pzhj 1870 23 ward ward NN cord-005646-xhx9pzhj 1870 24 and and CC cord-005646-xhx9pzhj 1870 25 8 8 CD cord-005646-xhx9pzhj 1870 26 ( ( -LRB- cord-005646-xhx9pzhj 1870 27 8 8 CD cord-005646-xhx9pzhj 1870 28 % % NN cord-005646-xhx9pzhj 1870 29 ) ) -RRB- cord-005646-xhx9pzhj 1870 30 in in IN cord-005646-xhx9pzhj 1870 31 the the DT cord-005646-xhx9pzhj 1870 32 operating operating NN cord-005646-xhx9pzhj 1870 33 room room NN cord-005646-xhx9pzhj 1870 34 . . . cord-005646-xhx9pzhj 1871 1 A a DT cord-005646-xhx9pzhj 1871 2 chronic chronic JJ cord-005646-xhx9pzhj 1871 3 underlying underlie VBG cord-005646-xhx9pzhj 1871 4 disease disease NN cord-005646-xhx9pzhj 1871 5 was be VBD cord-005646-xhx9pzhj 1871 6 present present JJ cord-005646-xhx9pzhj 1871 7 in in IN cord-005646-xhx9pzhj 1871 8 66 66 CD cord-005646-xhx9pzhj 1871 9 ( ( -LRB- cord-005646-xhx9pzhj 1871 10 67 67 CD cord-005646-xhx9pzhj 1871 11 % % NN cord-005646-xhx9pzhj 1871 12 ) ) -RRB- cord-005646-xhx9pzhj 1871 13 . . . cord-005646-xhx9pzhj 1872 1 Withholding withholding NN cord-005646-xhx9pzhj 1872 2 or or CC cord-005646-xhx9pzhj 1872 3 withdrawal withdrawal NN cord-005646-xhx9pzhj 1872 4 of of IN cord-005646-xhx9pzhj 1872 5 therapy therapy NN cord-005646-xhx9pzhj 1872 6 was be VBD cord-005646-xhx9pzhj 1872 7 implemented implement VBN cord-005646-xhx9pzhj 1872 8 in in IN cord-005646-xhx9pzhj 1872 9 48 48 CD cord-005646-xhx9pzhj 1872 10 ( ( -LRB- cord-005646-xhx9pzhj 1872 11 48 48 CD cord-005646-xhx9pzhj 1872 12 % % NN cord-005646-xhx9pzhj 1872 13 ) ) -RRB- cord-005646-xhx9pzhj 1872 14 children child NNS cord-005646-xhx9pzhj 1872 15 , , , cord-005646-xhx9pzhj 1872 16 27 27 CD cord-005646-xhx9pzhj 1872 17 ( ( -LRB- cord-005646-xhx9pzhj 1872 18 27 27 CD cord-005646-xhx9pzhj 1872 19 % % NN cord-005646-xhx9pzhj 1872 20 ) ) -RRB- cord-005646-xhx9pzhj 1872 21 died die VBD cord-005646-xhx9pzhj 1872 22 due due IN cord-005646-xhx9pzhj 1872 23 to to IN cord-005646-xhx9pzhj 1872 24 failed fail VBD cord-005646-xhx9pzhj 1872 25 CPR CPR NNP cord-005646-xhx9pzhj 1872 26 , , , cord-005646-xhx9pzhj 1872 27 20 20 CD cord-005646-xhx9pzhj 1872 28 ( ( -LRB- cord-005646-xhx9pzhj 1872 29 20 20 CD cord-005646-xhx9pzhj 1872 30 % % NN cord-005646-xhx9pzhj 1872 31 ) ) -RRB- cord-005646-xhx9pzhj 1872 32 were be VBD cord-005646-xhx9pzhj 1872 33 brain brain NN cord-005646-xhx9pzhj 1872 34 dead dead JJ cord-005646-xhx9pzhj 1872 35 and and CC cord-005646-xhx9pzhj 1872 36 4 4 CD cord-005646-xhx9pzhj 1872 37 ( ( -LRB- cord-005646-xhx9pzhj 1872 38 4 4 CD cord-005646-xhx9pzhj 1872 39 % % NN cord-005646-xhx9pzhj 1872 40 ) ) -RRB- cord-005646-xhx9pzhj 1872 41 died die VBD cord-005646-xhx9pzhj 1872 42 following follow VBG cord-005646-xhx9pzhj 1872 43 a a DT cord-005646-xhx9pzhj 1872 44 DNR DNR NNP cord-005646-xhx9pzhj 1872 45 order order NN cord-005646-xhx9pzhj 1872 46 . . . cord-005646-xhx9pzhj 1873 1 Justification justification NN cord-005646-xhx9pzhj 1873 2 for for IN cord-005646-xhx9pzhj 1873 3 therapeutic therapeutic JJ cord-005646-xhx9pzhj 1873 4 restrictions restriction NNS cord-005646-xhx9pzhj 1873 5 in in IN cord-005646-xhx9pzhj 1873 6 the the DT cord-005646-xhx9pzhj 1873 7 52 52 CD cord-005646-xhx9pzhj 1873 8 patients patient NNS cord-005646-xhx9pzhj 1873 9 of of IN cord-005646-xhx9pzhj 1873 10 the the DT cord-005646-xhx9pzhj 1873 11 DNR DNR NNP cord-005646-xhx9pzhj 1873 12 and and CC cord-005646-xhx9pzhj 1873 13 W W NNP cord-005646-xhx9pzhj 1873 14 / / SYM cord-005646-xhx9pzhj 1873 15 W W NNP cord-005646-xhx9pzhj 1873 16 groups group NNS cord-005646-xhx9pzhj 1873 17 was be VBD cord-005646-xhx9pzhj 1873 18 imminent imminent JJ cord-005646-xhx9pzhj 1873 19 death death NN cord-005646-xhx9pzhj 1873 20 in in IN cord-005646-xhx9pzhj 1873 21 32 32 CD cord-005646-xhx9pzhj 1873 22 ( ( -LRB- cord-005646-xhx9pzhj 1873 23 62 62 CD cord-005646-xhx9pzhj 1873 24 % % NN cord-005646-xhx9pzhj 1873 25 ) ) -RRB- cord-005646-xhx9pzhj 1873 26 , , , cord-005646-xhx9pzhj 1873 27 lack lack NN cord-005646-xhx9pzhj 1873 28 of of IN cord-005646-xhx9pzhj 1873 29 future future JJ cord-005646-xhx9pzhj 1873 30 relational relational JJ cord-005646-xhx9pzhj 1873 31 potential potential NN cord-005646-xhx9pzhj 1873 32 in in IN cord-005646-xhx9pzhj 1873 33 12 12 CD cord-005646-xhx9pzhj 1873 34 ( ( -LRB- cord-005646-xhx9pzhj 1873 35 23 23 CD cord-005646-xhx9pzhj 1873 36 % % NN cord-005646-xhx9pzhj 1873 37 ) ) -RRB- cord-005646-xhx9pzhj 1873 38 and and CC cord-005646-xhx9pzhj 1873 39 excessive excessive JJ cord-005646-xhx9pzhj 1873 40 health health NN cord-005646-xhx9pzhj 1873 41 burden burden NN cord-005646-xhx9pzhj 1873 42 in in IN cord-005646-xhx9pzhj 1873 43 8 8 CD cord-005646-xhx9pzhj 1873 44 ( ( -LRB- cord-005646-xhx9pzhj 1873 45 15 15 CD cord-005646-xhx9pzhj 1873 46 % % NN cord-005646-xhx9pzhj 1873 47 ) ) -RRB- cord-005646-xhx9pzhj 1873 48 . . . cord-005646-xhx9pzhj 1874 1 Withdrawal withdrawal NN cord-005646-xhx9pzhj 1874 2 or or CC cord-005646-xhx9pzhj 1874 3 withholding withholding NN cord-005646-xhx9pzhj 1874 4 of of IN cord-005646-xhx9pzhj 1874 5 therapy therapy NN cord-005646-xhx9pzhj 1874 6 was be VBD cord-005646-xhx9pzhj 1874 7 carried carry VBN cord-005646-xhx9pzhj 1874 8 out out RP cord-005646-xhx9pzhj 1874 9 by by IN cord-005646-xhx9pzhj 1874 10 extubation extubation NN cord-005646-xhx9pzhj 1874 11 in in IN cord-005646-xhx9pzhj 1874 12 46 46 CD cord-005646-xhx9pzhj 1874 13 % % NN cord-005646-xhx9pzhj 1874 14 , , , cord-005646-xhx9pzhj 1874 15 vasoactive vasoactive JJ cord-005646-xhx9pzhj 1874 16 drugs drug NNS cord-005646-xhx9pzhj 1874 17 were be VBD cord-005646-xhx9pzhj 1874 18 stopped stop VBN cord-005646-xhx9pzhj 1874 19 in in IN cord-005646-xhx9pzhj 1874 20 25 25 CD cord-005646-xhx9pzhj 1874 21 % % NN cord-005646-xhx9pzhj 1874 22 , , , cord-005646-xhx9pzhj 1874 23 and and CC cord-005646-xhx9pzhj 1874 24 mechanical mechanical JJ cord-005646-xhx9pzhj 1874 25 ventilation ventilation NN cord-005646-xhx9pzhj 1874 26 was be VBD cord-005646-xhx9pzhj 1874 27 withdrawn withdraw VBN cord-005646-xhx9pzhj 1874 28 in in IN cord-005646-xhx9pzhj 1874 29 21 21 CD cord-005646-xhx9pzhj 1874 30 % % NN cord-005646-xhx9pzhj 1874 31 , , , cord-005646-xhx9pzhj 1874 32 Analgetics Analgetics NNPS cord-005646-xhx9pzhj 1874 33 and and CC cord-005646-xhx9pzhj 1874 34 sedatives sedative NNS cord-005646-xhx9pzhj 1874 35 were be VBD cord-005646-xhx9pzhj 1874 36 frequently frequently RB cord-005646-xhx9pzhj 1874 37 used use VBN cord-005646-xhx9pzhj 1874 38 ( ( -LRB- cord-005646-xhx9pzhj 1874 39 in in IN cord-005646-xhx9pzhj 1874 40 73 73 CD cord-005646-xhx9pzhj 1874 41 % % NN cord-005646-xhx9pzhj 1874 42 and and CC cord-005646-xhx9pzhj 1874 43 79 79 CD cord-005646-xhx9pzhj 1874 44 % % NN cord-005646-xhx9pzhj 1874 45 , , , cord-005646-xhx9pzhj 1874 46 respectively respectively RB cord-005646-xhx9pzhj 1874 47 ) ) -RRB- cord-005646-xhx9pzhj 1874 48 . . . cord-005646-xhx9pzhj 1875 1 Hence hence RB cord-005646-xhx9pzhj 1875 2 decisions decision NNS cord-005646-xhx9pzhj 1875 3 concerning concern VBG cord-005646-xhx9pzhj 1875 4 restrictions restriction NNS cord-005646-xhx9pzhj 1875 5 of of IN cord-005646-xhx9pzhj 1875 6 treatment treatment NN cord-005646-xhx9pzhj 1875 7 are be VBP cord-005646-xhx9pzhj 1875 8 common common JJ cord-005646-xhx9pzhj 1875 9 in in IN cord-005646-xhx9pzhj 1875 10 pediatric pediatric JJ cord-005646-xhx9pzhj 1875 11 practice practice NN cord-005646-xhx9pzhj 1875 12 , , , cord-005646-xhx9pzhj 1875 13 mostly mostly RB cord-005646-xhx9pzhj 1875 14 due due JJ cord-005646-xhx9pzhj 1875 15 to to IN cord-005646-xhx9pzhj 1875 16 imminent imminent JJ cord-005646-xhx9pzhj 1875 17 death death NN cord-005646-xhx9pzhj 1875 18 . . . cord-005646-xhx9pzhj 1876 1 Patients patient NNS cord-005646-xhx9pzhj 1876 2 in in IN cord-005646-xhx9pzhj 1876 3 which which WDT cord-005646-xhx9pzhj 1876 4 treatment treatment NN cord-005646-xhx9pzhj 1876 5 was be VBD cord-005646-xhx9pzhj 1876 6 restricted restrict VBN cord-005646-xhx9pzhj 1876 7 were be VBD cord-005646-xhx9pzhj 1876 8 characterised characterise VBN cord-005646-xhx9pzhj 1876 9 by by IN cord-005646-xhx9pzhj 1876 10 a a DT cord-005646-xhx9pzhj 1876 11 longer long JJR cord-005646-xhx9pzhj 1876 12 hospital hospital NN cord-005646-xhx9pzhj 1876 13 stay stay NN cord-005646-xhx9pzhj 1876 14 , , , cord-005646-xhx9pzhj 1876 15 a a DT cord-005646-xhx9pzhj 1876 16 worse bad JJR cord-005646-xhx9pzhj 1876 17 prognosis prognosis NN cord-005646-xhx9pzhj 1876 18 , , , cord-005646-xhx9pzhj 1876 19 a a DT cord-005646-xhx9pzhj 1876 20 higher high JJR cord-005646-xhx9pzhj 1876 21 frequency frequency NN cord-005646-xhx9pzhj 1876 22 of of IN cord-005646-xhx9pzhj 1876 23 chronic chronic JJ cord-005646-xhx9pzhj 1876 24 underlying underlie VBG cord-005646-xhx9pzhj 1876 25 diseases disease NNS cord-005646-xhx9pzhj 1876 26 and and CC cord-005646-xhx9pzhj 1876 27 a a DT cord-005646-xhx9pzhj 1876 28 lower low JJR cord-005646-xhx9pzhj 1876 29 acute acute JJ cord-005646-xhx9pzhj 1876 30 mortality mortality NN cord-005646-xhx9pzhj 1876 31 risk risk NN cord-005646-xhx9pzhj 1876 32 . . . cord-005646-xhx9pzhj 1877 1 Despite despite IN cord-005646-xhx9pzhj 1877 2 restrictions restriction NNS cord-005646-xhx9pzhj 1877 3 of of IN cord-005646-xhx9pzhj 1877 4 intensive intensive JJ cord-005646-xhx9pzhj 1877 5 therapy therapy NN cord-005646-xhx9pzhj 1877 6 , , , cord-005646-xhx9pzhj 1877 7 most most JJS cord-005646-xhx9pzhj 1877 8 patients patient NNS cord-005646-xhx9pzhj 1877 9 were be VBD cord-005646-xhx9pzhj 1877 10 allowed allow VBN cord-005646-xhx9pzhj 1877 11 to to TO cord-005646-xhx9pzhj 1877 12 die die VB cord-005646-xhx9pzhj 1877 13 in in IN cord-005646-xhx9pzhj 1877 14 the the DT cord-005646-xhx9pzhj 1877 15 pediatric pediatric JJ cord-005646-xhx9pzhj 1877 16 ICU ICU NNP cord-005646-xhx9pzhj 1877 17 . . . cord-005646-xhx9pzhj 1878 1 Background Background NNP cord-005646-xhx9pzhj 1878 2 Microalbuminuria Microalbuminuria NNP cord-005646-xhx9pzhj 1878 3 ( ( -LRB- cord-005646-xhx9pzhj 1878 4 MCA MCA NNP cord-005646-xhx9pzhj 1878 5 ) ) -RRB- cord-005646-xhx9pzhj 1878 6 , , , cord-005646-xhx9pzhj 1878 7 a a DT cord-005646-xhx9pzhj 1878 8 subclinical subclinical JJ cord-005646-xhx9pzhj 1878 9 increase increase NN cord-005646-xhx9pzhj 1878 10 in in IN cord-005646-xhx9pzhj 1878 11 urinary urinary JJ cord-005646-xhx9pzhj 1878 12 albumin albumin NN cord-005646-xhx9pzhj 1878 13 , , , cord-005646-xhx9pzhj 1878 14 reflects reflect VBZ cord-005646-xhx9pzhj 1878 15 glomerular glomerular JJ cord-005646-xhx9pzhj 1878 16 and and CC cord-005646-xhx9pzhj 1878 17 overall overall JJ cord-005646-xhx9pzhj 1878 18 vascular vascular JJ cord-005646-xhx9pzhj 1878 19 permeability permeability NN cord-005646-xhx9pzhj 1878 20 1"2 1"2 CD cord-005646-xhx9pzhj 1878 21 . . . cord-005646-xhx9pzhj 1879 1 An an DT cord-005646-xhx9pzhj 1879 2 increase increase NN cord-005646-xhx9pzhj 1879 3 in in IN cord-005646-xhx9pzhj 1879 4 urinary urinary JJ cord-005646-xhx9pzhj 1879 5 excretion excretion NN cord-005646-xhx9pzhj 1879 6 of of IN cord-005646-xhx9pzhj 1879 7 albumin albumin NN cord-005646-xhx9pzhj 1879 8 occurs occur VBZ cord-005646-xhx9pzhj 1879 9 after after IN cord-005646-xhx9pzhj 1879 10 burns burn NNS cord-005646-xhx9pzhj 1879 11 and and CC cord-005646-xhx9pzhj 1879 12 trauma trauma NN cord-005646-xhx9pzhj 1879 13 . . . cord-005646-xhx9pzhj 1880 1 Transcanillary transcanillary JJ cord-005646-xhx9pzhj 1880 2 albumin albumin NN cord-005646-xhx9pzhj 1880 3 escape escape NN cord-005646-xhx9pzhj 1880 4 rate rate NN cord-005646-xhx9pzhj 1880 5 is be VBZ cord-005646-xhx9pzhj 1880 6 also also RB cord-005646-xhx9pzhj 1880 7 increased increase VBN cord-005646-xhx9pzhj 1880 8 in in IN cord-005646-xhx9pzhj 1880 9 response response NN cord-005646-xhx9pzhj 1880 10 to to IN cord-005646-xhx9pzhj 1880 11 elective elective JJ cord-005646-xhx9pzhj 1880 12 surgery surgery NN cord-005646-xhx9pzhj 1880 13 3 3 CD cord-005646-xhx9pzhj 1880 14 and and CC cord-005646-xhx9pzhj 1880 15 in in IN cord-005646-xhx9pzhj 1880 16 critically critically RB cord-005646-xhx9pzhj 1880 17 ill ill JJ cord-005646-xhx9pzhj 1880 18 adult adult NN cord-005646-xhx9pzhj 1880 19 patients patient NNS cord-005646-xhx9pzhj 1880 20 4 4 CD cord-005646-xhx9pzhj 1880 21 . . . cord-005646-xhx9pzhj 1881 1 We -PRON- PRP cord-005646-xhx9pzhj 1881 2 investigated investigate VBD cord-005646-xhx9pzhj 1881 3 a a DT cord-005646-xhx9pzhj 1881 4 possible possible JJ cord-005646-xhx9pzhj 1881 5 relationship relationship NN cord-005646-xhx9pzhj 1881 6 between between IN cord-005646-xhx9pzhj 1881 7 urinary urinary JJ cord-005646-xhx9pzhj 1881 8 albumin albumin NN cord-005646-xhx9pzhj 1881 9 levels level NNS cord-005646-xhx9pzhj 1881 10 and and CC cord-005646-xhx9pzhj 1881 11 clinical clinical JJ cord-005646-xhx9pzhj 1881 12 instability instability NN cord-005646-xhx9pzhj 1881 13 , , , cord-005646-xhx9pzhj 1881 14 as as IN cord-005646-xhx9pzhj 1881 15 measured measure VBN cord-005646-xhx9pzhj 1881 16 by by IN cord-005646-xhx9pzhj 1881 17 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1881 18 Risk Risk NNP cord-005646-xhx9pzhj 1881 19 of of IN cord-005646-xhx9pzhj 1881 20 Mortality Mortality NNP cord-005646-xhx9pzhj 1881 21 ( ( -LRB- cord-005646-xhx9pzhj 1881 22 PRISM PRISM NNP cord-005646-xhx9pzhj 1881 23 ) ) -RRB- cord-005646-xhx9pzhj 1881 24 scores score NNS cord-005646-xhx9pzhj 1881 25 . . . cord-005646-xhx9pzhj 1882 1 Method method NN cord-005646-xhx9pzhj 1882 2 We -PRON- PRP cord-005646-xhx9pzhj 1882 3 studied study VBD cord-005646-xhx9pzhj 1882 4 26 26 CD cord-005646-xhx9pzhj 1882 5 consecutive consecutive JJ cord-005646-xhx9pzhj 1882 6 patients patient NNS cord-005646-xhx9pzhj 1882 7 ( ( -LRB- cord-005646-xhx9pzhj 1882 8 median median JJ cord-005646-xhx9pzhj 1882 9 age age NN cord-005646-xhx9pzhj 1882 10 of of IN cord-005646-xhx9pzhj 1882 11 13 13 CD cord-005646-xhx9pzhj 1882 12 months month NNS cord-005646-xhx9pzhj 1882 13 , , , cord-005646-xhx9pzhj 1882 14 range range VBP cord-005646-xhx9pzhj 1882 15 2 2 CD cord-005646-xhx9pzhj 1882 16 - - SYM cord-005646-xhx9pzhj 1882 17 100 100 CD cord-005646-xhx9pzhj 1882 18 ) ) -RRB- cord-005646-xhx9pzhj 1882 19 . . . cord-005646-xhx9pzhj 1883 1 Patients patient NNS cord-005646-xhx9pzhj 1883 2 whith whith JJ cord-005646-xhx9pzhj 1883 3 nephropathies nephropathy NNS cord-005646-xhx9pzhj 1883 4 or or CC cord-005646-xhx9pzhj 1883 5 any any DT cord-005646-xhx9pzhj 1883 6 abnormality abnormality NN cord-005646-xhx9pzhj 1883 7 of of IN cord-005646-xhx9pzhj 1883 8 urine urine NN cord-005646-xhx9pzhj 1883 9 analysis analysis NN cord-005646-xhx9pzhj 1883 10 were be VBD cord-005646-xhx9pzhj 1883 11 excluded exclude VBN cord-005646-xhx9pzhj 1883 12 from from IN cord-005646-xhx9pzhj 1883 13 the the DT cord-005646-xhx9pzhj 1883 14 analysis analysis NN cord-005646-xhx9pzhj 1883 15 . . . cord-005646-xhx9pzhj 1884 1 PRISM prism NN cord-005646-xhx9pzhj 1884 2 scores score NNS cord-005646-xhx9pzhj 1884 3 , , , cord-005646-xhx9pzhj 1884 4 MCA MCA NNP cord-005646-xhx9pzhj 1884 5 ( ( -LRB- cord-005646-xhx9pzhj 1884 6 mg.1 mg.1 NNP cord-005646-xhx9pzhj 1884 7 - - HYPH cord-005646-xhx9pzhj 1884 8 1 1 CD cord-005646-xhx9pzhj 1884 9 ) ) -RRB- cord-005646-xhx9pzhj 1884 10 ( ( -LRB- cord-005646-xhx9pzhj 1884 11 immunonepbelometric immunonepbelometric NNP cord-005646-xhx9pzhj 1884 12 ) ) -RRB- cord-005646-xhx9pzhj 1884 13 and and CC cord-005646-xhx9pzhj 1884 14 urinary urinary JJ cord-005646-xhx9pzhj 1884 15 creatinine creatinine NN cord-005646-xhx9pzhj 1884 16 ( ( -LRB- cord-005646-xhx9pzhj 1884 17 Cu Cu NNP cord-005646-xhx9pzhj 1884 18 ) ) -RRB- cord-005646-xhx9pzhj 1885 1 ( ( -LRB- cord-005646-xhx9pzhj 1885 2 mmol.l mmol.l NNP cord-005646-xhx9pzhj 1885 3 - - HYPH cord-005646-xhx9pzhj 1885 4 ! ! . cord-005646-xhx9pzhj 1885 5 ) ) -RRB- cord-005646-xhx9pzhj 1886 1 ( ( -LRB- cord-005646-xhx9pzhj 1886 2 Jaffb Jaffb NNP cord-005646-xhx9pzhj 1886 3 ) ) -RRB- cord-005646-xhx9pzhj 1886 4 ( ( -LRB- cord-005646-xhx9pzhj 1886 5 48 48 CD cord-005646-xhx9pzhj 1886 6 hour hour NN cord-005646-xhx9pzhj 1886 7 collection collection NN cord-005646-xhx9pzhj 1886 8 sample sample NN cord-005646-xhx9pzhj 1886 9 ) ) -RRB- cord-005646-xhx9pzhj 1886 10 were be VBD cord-005646-xhx9pzhj 1886 11 determined determine VBN cord-005646-xhx9pzhj 1886 12 within within IN cord-005646-xhx9pzhj 1886 13 48 48 CD cord-005646-xhx9pzhj 1886 14 hours hour NNS cord-005646-xhx9pzhj 1886 15 from from IN cord-005646-xhx9pzhj 1886 16 admission admission NN cord-005646-xhx9pzhj 1886 17 to to IN cord-005646-xhx9pzhj 1886 18 the the DT cord-005646-xhx9pzhj 1886 19 PICU PICU NNP cord-005646-xhx9pzhj 1886 20 . . . cord-005646-xhx9pzhj 1887 1 The the DT cord-005646-xhx9pzhj 1887 2 MCA MCA NNP cord-005646-xhx9pzhj 1887 3 / / SYM cord-005646-xhx9pzhj 1887 4 Cu Cu NNP cord-005646-xhx9pzhj 1887 5 ratio ratio NN cord-005646-xhx9pzhj 1887 6 ( ( -LRB- cord-005646-xhx9pzhj 1887 7 mg.mmol.1 mg.mmol.1 NNP cord-005646-xhx9pzhj 1887 8 " " '' cord-005646-xhx9pzhj 1887 9 l l NN cord-005646-xhx9pzhj 1887 10 ) ) -RRB- cord-005646-xhx9pzhj 1887 11 was be VBD cord-005646-xhx9pzhj 1887 12 used use VBN cord-005646-xhx9pzhj 1887 13 to to TO cord-005646-xhx9pzhj 1887 14 correct correct VB cord-005646-xhx9pzhj 1887 15 for for IN cord-005646-xhx9pzhj 1887 16 urine urine NN cord-005646-xhx9pzhj 1887 17 output output NN cord-005646-xhx9pzhj 1887 18 variability variability NN cord-005646-xhx9pzhj 1887 19 . . . cord-005646-xhx9pzhj 1888 1 Diagnoses diagnosis NNS cord-005646-xhx9pzhj 1888 2 included include VBD cord-005646-xhx9pzhj 1888 3 respiratory respiratory JJ cord-005646-xhx9pzhj 1888 4 failure failure NN cord-005646-xhx9pzhj 1888 5 ( ( -LRB- cord-005646-xhx9pzhj 1888 6 6 6 CD cord-005646-xhx9pzhj 1888 7 ) ) -RRB- cord-005646-xhx9pzhj 1888 8 , , , cord-005646-xhx9pzhj 1888 9 postoperative postoperative JJ cord-005646-xhx9pzhj 1888 10 ( ( -LRB- cord-005646-xhx9pzhj 1888 11 5 5 CD cord-005646-xhx9pzhj 1888 12 ) ) -RRB- cord-005646-xhx9pzhj 1888 13 , , , cord-005646-xhx9pzhj 1888 14 neurologic neurologic JJ cord-005646-xhx9pzhj 1888 15 ( ( -LRB- cord-005646-xhx9pzhj 1888 16 5 5 CD cord-005646-xhx9pzhj 1888 17 ) ) -RRB- cord-005646-xhx9pzhj 1888 18 , , , cord-005646-xhx9pzhj 1888 19 sepsis sepsis NN cord-005646-xhx9pzhj 1888 20 ( ( -LRB- cord-005646-xhx9pzhj 1888 21 4 4 CD cord-005646-xhx9pzhj 1888 22 ) ) -RRB- cord-005646-xhx9pzhj 1888 23 , , , cord-005646-xhx9pzhj 1888 24 trauma trauma NN cord-005646-xhx9pzhj 1888 25 ( ( -LRB- cord-005646-xhx9pzhj 1888 26 3 3 CD cord-005646-xhx9pzhj 1888 27 ) ) -RRB- cord-005646-xhx9pzhj 1888 28 and and CC cord-005646-xhx9pzhj 1888 29 miscellaneous miscellaneous JJ cord-005646-xhx9pzhj 1888 30 cases case NNS cord-005646-xhx9pzhj 1888 31 ( ( -LRB- cord-005646-xhx9pzhj 1888 32 3 3 CD cord-005646-xhx9pzhj 1888 33 ) ) -RRB- cord-005646-xhx9pzhj 1888 34 . . . cord-005646-xhx9pzhj 1889 1 Pearson Pearson NNP cord-005646-xhx9pzhj 1889 2 's 's POS cord-005646-xhx9pzhj 1889 3 correlation correlation NN cord-005646-xhx9pzhj 1889 4 was be VBD cord-005646-xhx9pzhj 1889 5 performed perform VBN cord-005646-xhx9pzhj 1889 6 to to TO cord-005646-xhx9pzhj 1889 7 correlate correlate VB cord-005646-xhx9pzhj 1889 8 data datum NNS cord-005646-xhx9pzhj 1889 9 . . . cord-005646-xhx9pzhj 1890 1 Results result NNS cord-005646-xhx9pzhj 1890 2 and and CC cord-005646-xhx9pzhj 1890 3 Conclusions Conclusions NNPS cord-005646-xhx9pzhj 1890 4 . . . cord-005646-xhx9pzhj 1891 1 Mean mean JJ cord-005646-xhx9pzhj 1891 2 PRISM prism NN cord-005646-xhx9pzhj 1891 3 score score NN cord-005646-xhx9pzhj 1891 4 and and CC cord-005646-xhx9pzhj 1891 5 MCA MCA NNP cord-005646-xhx9pzhj 1891 6 / / SYM cord-005646-xhx9pzhj 1891 7 Cu Cu NNP cord-005646-xhx9pzhj 1891 8 were be VBD cord-005646-xhx9pzhj 1891 9 16.9 16.9 CD cord-005646-xhx9pzhj 1891 10 ± ± CD cord-005646-xhx9pzhj 1891 11 5.9 5.9 CD cord-005646-xhx9pzhj 1891 12 SD sd NN cord-005646-xhx9pzhj 1891 13 and and CC cord-005646-xhx9pzhj 1891 14 1004 1004 CD cord-005646-xhx9pzhj 1891 15 - - SYM cord-005646-xhx9pzhj 1891 16 39 39 CD cord-005646-xhx9pzhj 1891 17 SD sd NN cord-005646-xhx9pzhj 1891 18 , , , cord-005646-xhx9pzhj 1891 19 respectively respectively RB cord-005646-xhx9pzhj 1891 20 . . . cord-005646-xhx9pzhj 1892 1 A a DT cord-005646-xhx9pzhj 1892 2 significant significant JJ cord-005646-xhx9pzhj 1892 3 correlation correlation NN cord-005646-xhx9pzhj 1892 4 was be VBD cord-005646-xhx9pzhj 1892 5 found find VBN cord-005646-xhx9pzhj 1892 6 between between IN cord-005646-xhx9pzhj 1892 7 MCA MCA NNP cord-005646-xhx9pzhj 1892 8 / / SYM cord-005646-xhx9pzhj 1892 9 Cu Cu NNP cord-005646-xhx9pzhj 1892 10 and and CC cord-005646-xhx9pzhj 1892 11 PRISM PRISM NNP cord-005646-xhx9pzhj 1892 12 scores score NNS cord-005646-xhx9pzhj 1892 13 ( ( -LRB- cord-005646-xhx9pzhj 1892 14 R=0.80 r=0.80 NN cord-005646-xhx9pzhj 1892 15 , , , cord-005646-xhx9pzhj 1892 16 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 1892 17 ) ) -RRB- cord-005646-xhx9pzhj 1892 18 . . . cord-005646-xhx9pzhj 1893 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 1893 2 observations observation NNS cord-005646-xhx9pzhj 1893 3 show show VBP cord-005646-xhx9pzhj 1893 4 that that IN cord-005646-xhx9pzhj 1893 5 , , , cord-005646-xhx9pzhj 1893 6 independently independently RB cord-005646-xhx9pzhj 1893 7 of of IN cord-005646-xhx9pzhj 1893 8 the the DT cord-005646-xhx9pzhj 1893 9 initial initial JJ cord-005646-xhx9pzhj 1893 10 insult insult NN cord-005646-xhx9pzhj 1893 11 , , , cord-005646-xhx9pzhj 1893 12 the the DT cord-005646-xhx9pzhj 1893 13 paediatric paediatric JJ cord-005646-xhx9pzhj 1893 14 unstable unstable JJ cord-005646-xhx9pzhj 1893 15 patient patient NN cord-005646-xhx9pzhj 1893 16 may may MD cord-005646-xhx9pzhj 1893 17 have have VB cord-005646-xhx9pzhj 1893 18 increased increase VBN cord-005646-xhx9pzhj 1893 19 capillary capillary JJ cord-005646-xhx9pzhj 1893 20 permeability permeability NN cord-005646-xhx9pzhj 1893 21 , , , cord-005646-xhx9pzhj 1893 22 which which WDT cord-005646-xhx9pzhj 1893 23 is be VBZ cord-005646-xhx9pzhj 1893 24 correlated correlate VBN cord-005646-xhx9pzhj 1893 25 with with IN cord-005646-xhx9pzhj 1893 26 the the DT cord-005646-xhx9pzhj 1893 27 degree degree NN cord-005646-xhx9pzhj 1893 28 of of IN cord-005646-xhx9pzhj 1893 29 physiological physiological JJ cord-005646-xhx9pzhj 1893 30 derangement derangement NN cord-005646-xhx9pzhj 1893 31 , , , cord-005646-xhx9pzhj 1893 32 as as IN cord-005646-xhx9pzhj 1893 33 measured measure VBN cord-005646-xhx9pzhj 1893 34 by by IN cord-005646-xhx9pzhj 1893 35 PRISM PRISM NNP cord-005646-xhx9pzhj 1893 36 scores score NNS cord-005646-xhx9pzhj 1893 37 . . . cord-005646-xhx9pzhj 1894 1 Microalbuminuria Microalbuminuria NNP cord-005646-xhx9pzhj 1894 2 can can MD cord-005646-xhx9pzhj 1894 3 be be VB cord-005646-xhx9pzhj 1894 4 rapidly rapidly RB cord-005646-xhx9pzhj 1894 5 determined determine VBN cord-005646-xhx9pzhj 1894 6 since since IN cord-005646-xhx9pzhj 1894 7 it -PRON- PRP cord-005646-xhx9pzhj 1894 8 is be VBZ cord-005646-xhx9pzhj 1894 9 routinely routinely RB cord-005646-xhx9pzhj 1894 10 used use VBN cord-005646-xhx9pzhj 1894 11 in in IN cord-005646-xhx9pzhj 1894 12 the the DT cord-005646-xhx9pzhj 1894 13 management management NN cord-005646-xhx9pzhj 1894 14 of of IN cord-005646-xhx9pzhj 1894 15 diabetic diabetic JJ cord-005646-xhx9pzhj 1894 16 patients patient NNS cord-005646-xhx9pzhj 1894 17 , , , cord-005646-xhx9pzhj 1894 18 it -PRON- PRP cord-005646-xhx9pzhj 1894 19 is be VBZ cord-005646-xhx9pzhj 1894 20 inexpensive inexpensive JJ cord-005646-xhx9pzhj 1894 21 , , , cord-005646-xhx9pzhj 1894 22 simple simple JJ cord-005646-xhx9pzhj 1894 23 to to TO cord-005646-xhx9pzhj 1894 24 measure measure VB cord-005646-xhx9pzhj 1894 25 and and CC cord-005646-xhx9pzhj 1894 26 blood blood NN cord-005646-xhx9pzhj 1894 27 - - HYPH cord-005646-xhx9pzhj 1894 28 spearing spearing NN cord-005646-xhx9pzhj 1894 29 . . . cord-005646-xhx9pzhj 1895 1 Therefore therefore RB cord-005646-xhx9pzhj 1895 2 , , , cord-005646-xhx9pzhj 1895 3 it -PRON- PRP cord-005646-xhx9pzhj 1895 4 might may MD cord-005646-xhx9pzhj 1895 5 have have VB cord-005646-xhx9pzhj 1895 6 a a DT cord-005646-xhx9pzhj 1895 7 role role NN cord-005646-xhx9pzhj 1895 8 in in IN cord-005646-xhx9pzhj 1895 9 the the DT cord-005646-xhx9pzhj 1895 10 clinical clinical JJ cord-005646-xhx9pzhj 1895 11 assessment assessment NN cord-005646-xhx9pzhj 1895 12 of of IN cord-005646-xhx9pzhj 1895 13 capillary capillary JJ cord-005646-xhx9pzhj 1895 14 permeability permeability NN cord-005646-xhx9pzhj 1895 15 and and CC cord-005646-xhx9pzhj 1895 16 transcapillary transcapillary JJ cord-005646-xhx9pzhj 1895 17 albumin albumin NN cord-005646-xhx9pzhj 1895 18 escape escape NN cord-005646-xhx9pzhj 1896 1 Worldwide worldwide RB cord-005646-xhx9pzhj 1897 1 the the DT cord-005646-xhx9pzhj 1897 2 demand demand NN cord-005646-xhx9pzhj 1897 3 for for IN cord-005646-xhx9pzhj 1897 4 paediatric paediatric JJ cord-005646-xhx9pzhj 1897 5 intensive intensive JJ cord-005646-xhx9pzhj 1897 6 care care NN cord-005646-xhx9pzhj 1897 7 services service NNS cord-005646-xhx9pzhj 1897 8 exceeds exceed VBZ cord-005646-xhx9pzhj 1897 9 the the DT cord-005646-xhx9pzhj 1897 10 supply supply NN cord-005646-xhx9pzhj 1897 11 . . . cord-005646-xhx9pzhj 1898 1 In in IN cord-005646-xhx9pzhj 1898 2 developing develop VBG cord-005646-xhx9pzhj 1898 3 countries country NNS cord-005646-xhx9pzhj 1898 4 sporadic sporadic JJ cord-005646-xhx9pzhj 1898 5 access access NN cord-005646-xhx9pzhj 1898 6 to to IN cord-005646-xhx9pzhj 1898 7 such such JJ cord-005646-xhx9pzhj 1898 8 services service NNS cord-005646-xhx9pzhj 1898 9 alters alter VBZ cord-005646-xhx9pzhj 1898 10 expectation expectation NN cord-005646-xhx9pzhj 1898 11 of of IN cord-005646-xhx9pzhj 1898 12 care care NN cord-005646-xhx9pzhj 1898 13 and and CC cord-005646-xhx9pzhj 1898 14 can can MD cord-005646-xhx9pzhj 1898 15 lead lead VB cord-005646-xhx9pzhj 1898 16 to to IN cord-005646-xhx9pzhj 1898 17 children child NNS cord-005646-xhx9pzhj 1898 18 being be VBG cord-005646-xhx9pzhj 1898 19 either either CC cord-005646-xhx9pzhj 1898 20 mechanically mechanically RB cord-005646-xhx9pzhj 1898 21 or or CC cord-005646-xhx9pzhj 1898 22 handventilated handventilate VBN cord-005646-xhx9pzhj 1898 23 in in IN cord-005646-xhx9pzhj 1898 24 general general JJ cord-005646-xhx9pzhj 1898 25 paediatric paediatric JJ cord-005646-xhx9pzhj 1898 26 wards ward NNS cord-005646-xhx9pzhj 1898 27 . . . cord-005646-xhx9pzhj 1899 1 The the DT cord-005646-xhx9pzhj 1899 2 outcome outcome NN cord-005646-xhx9pzhj 1899 3 of of IN cord-005646-xhx9pzhj 1899 4 children child NNS cord-005646-xhx9pzhj 1899 5 requiring require VBG cord-005646-xhx9pzhj 1899 6 ventilation ventilation NN cord-005646-xhx9pzhj 1899 7 in in IN cord-005646-xhx9pzhj 1899 8 a a DT cord-005646-xhx9pzhj 1899 9 major major JJ cord-005646-xhx9pzhj 1899 10 teaching teaching NN cord-005646-xhx9pzhj 1899 11 hospital hospital NN cord-005646-xhx9pzhj 1899 12 in in IN cord-005646-xhx9pzhj 1899 13 India India NNP cord-005646-xhx9pzhj 1899 14 was be VBD cord-005646-xhx9pzhj 1899 15 reviewed review VBN cord-005646-xhx9pzhj 1899 16 . . . cord-005646-xhx9pzhj 1900 1 Children child NNS cord-005646-xhx9pzhj 1900 2 were be VBD cord-005646-xhx9pzhj 1900 3 ventilated ventilate VBN cord-005646-xhx9pzhj 1900 4 on on IN cord-005646-xhx9pzhj 1900 5 an an DT cord-005646-xhx9pzhj 1900 6 adult adult NN cord-005646-xhx9pzhj 1900 7 intensive intensive JJ cord-005646-xhx9pzhj 1900 8 care care NN cord-005646-xhx9pzhj 1900 9 unit unit NN cord-005646-xhx9pzhj 1900 10 ( ( -LRB- cord-005646-xhx9pzhj 1900 11 AICU AICU NNP cord-005646-xhx9pzhj 1900 12 ) ) -RRB- cord-005646-xhx9pzhj 1900 13 if if IN cord-005646-xhx9pzhj 1900 14 a a DT cord-005646-xhx9pzhj 1900 15 bed bed NN cord-005646-xhx9pzhj 1900 16 was be VBD cord-005646-xhx9pzhj 1900 17 available available JJ cord-005646-xhx9pzhj 1900 18 , , , cord-005646-xhx9pzhj 1900 19 otherwise otherwise RB cord-005646-xhx9pzhj 1900 20 in in IN cord-005646-xhx9pzhj 1900 21 the the DT cord-005646-xhx9pzhj 1900 22 general general JJ cord-005646-xhx9pzhj 1900 23 paediatric paediatric JJ cord-005646-xhx9pzhj 1900 24 wards ward NNS cord-005646-xhx9pzhj 1900 25 . . . cord-005646-xhx9pzhj 1901 1 Over over IN cord-005646-xhx9pzhj 1901 2 a a DT cord-005646-xhx9pzhj 1901 3 4 4 CD cord-005646-xhx9pzhj 1901 4 year year NN cord-005646-xhx9pzhj 1901 5 period period NN cord-005646-xhx9pzhj 1901 6 109 109 CD cord-005646-xhx9pzhj 1901 7 children child NNS cord-005646-xhx9pzhj 1901 8 were be VBD cord-005646-xhx9pzhj 1901 9 ventilated ventilate VBN cord-005646-xhx9pzhj 1901 10 on on IN cord-005646-xhx9pzhj 1901 11 AICU AICU NNP cord-005646-xhx9pzhj 1901 12 with with IN cord-005646-xhx9pzhj 1901 13 54 54 CD cord-005646-xhx9pzhj 1901 14 deaths death NNS cord-005646-xhx9pzhj 1901 15 . . . cord-005646-xhx9pzhj 1902 1 Yearly yearly JJ cord-005646-xhx9pzhj 1902 2 mortality mortality NN cord-005646-xhx9pzhj 1902 3 rates rate NNS cord-005646-xhx9pzhj 1902 4 varied vary VBN cord-005646-xhx9pzhj 1902 5 between between IN cord-005646-xhx9pzhj 1902 6 43 43 CD cord-005646-xhx9pzhj 1902 7 - - SYM cord-005646-xhx9pzhj 1902 8 58 58 CD cord-005646-xhx9pzhj 1902 9 % % NN cord-005646-xhx9pzhj 1902 10 . . . cord-005646-xhx9pzhj 1903 1 Over over IN cord-005646-xhx9pzhj 1903 2 a a DT cord-005646-xhx9pzhj 1903 3 3 3 CD cord-005646-xhx9pzhj 1903 4 month month NN cord-005646-xhx9pzhj 1903 5 period period NN cord-005646-xhx9pzhj 1903 6 37 37 CD cord-005646-xhx9pzhj 1903 7 patients patient NNS cord-005646-xhx9pzhj 1903 8 were be VBD cord-005646-xhx9pzhj 1903 9 ventilated ventilate VBN cord-005646-xhx9pzhj 1903 10 on on IN cord-005646-xhx9pzhj 1903 11 the the DT cord-005646-xhx9pzhj 1903 12 paediatric paediatric JJ cord-005646-xhx9pzhj 1903 13 wards ward NNS cord-005646-xhx9pzhj 1903 14 . . . cord-005646-xhx9pzhj 1904 1 Of of IN cord-005646-xhx9pzhj 1904 2 the the DT cord-005646-xhx9pzhj 1904 3 15 15 CD cord-005646-xhx9pzhj 1904 4 p p NN cord-005646-xhx9pzhj 1904 5 ~ ~ CD cord-005646-xhx9pzhj 1904 6 tients tient NNS cord-005646-xhx9pzhj 1904 7 over over IN cord-005646-xhx9pzhj 1904 8 4 4 CD cord-005646-xhx9pzhj 1904 9 weeks week NNS cord-005646-xhx9pzhj 1904 10 of of IN cord-005646-xhx9pzhj 1904 11 age age NN cord-005646-xhx9pzhj 1904 12 11 11 CD cord-005646-xhx9pzhj 1904 13 died die VBD cord-005646-xhx9pzhj 1905 1 ( ( -LRB- cord-005646-xhx9pzhj 1905 2 Chi Chi NNP cord-005646-xhx9pzhj 1905 3 squared square VBD cord-005646-xhx9pzhj 1905 4 0.t 0.t CD cord-005646-xhx9pzhj 1906 1 > > XX cord-005646-xhx9pzhj 1907 1 P>0.05 P>0.05 NNP cord-005646-xhx9pzhj 1907 2 ) ) -RRB- cord-005646-xhx9pzhj 1907 3 Reasons reason NNS cord-005646-xhx9pzhj 1907 4 for for IN cord-005646-xhx9pzhj 1907 5 the the DT cord-005646-xhx9pzhj 1907 6 higher high JJR cord-005646-xhx9pzhj 1907 7 mortality mortality NN cord-005646-xhx9pzhj 1907 8 rate rate NN cord-005646-xhx9pzhj 1907 9 on on IN cord-005646-xhx9pzhj 1907 10 the the DT cord-005646-xhx9pzhj 1907 11 paediatric paediatric JJ cord-005646-xhx9pzhj 1907 12 ward ward NN cord-005646-xhx9pzhj 1907 13 likely likely RB cord-005646-xhx9pzhj 1907 14 include include VBP cord-005646-xhx9pzhj 1907 15 the the DT cord-005646-xhx9pzhj 1907 16 higher high JJR cord-005646-xhx9pzhj 1907 17 patient patient NN cord-005646-xhx9pzhj 1907 18 : : : cord-005646-xhx9pzhj 1907 19 nurse nurse NN cord-005646-xhx9pzhj 1907 20 ratio ratio NN cord-005646-xhx9pzhj 1907 21 , , , cord-005646-xhx9pzhj 1907 22 and and CC cord-005646-xhx9pzhj 1907 23 more more RBR cord-005646-xhx9pzhj 1907 24 limited limited JJ cord-005646-xhx9pzhj 1907 25 resources resource NNS cord-005646-xhx9pzhj 1907 26 . . . cord-005646-xhx9pzhj 1908 1 A a DT cord-005646-xhx9pzhj 1908 2 predictor predictor NN cord-005646-xhx9pzhj 1908 3 of of IN cord-005646-xhx9pzhj 1908 4 mortality mortality NN cord-005646-xhx9pzhj 1908 5 based base VBN cord-005646-xhx9pzhj 1908 6 on on IN cord-005646-xhx9pzhj 1908 7 simple simple JJ cord-005646-xhx9pzhj 1908 8 physiological physiological JJ cord-005646-xhx9pzhj 1908 9 observations observation NNS cord-005646-xhx9pzhj 1908 10 without without IN cord-005646-xhx9pzhj 1908 11 the the DT cord-005646-xhx9pzhj 1908 12 need need NN cord-005646-xhx9pzhj 1908 13 for for IN cord-005646-xhx9pzhj 1908 14 expensive expensive JJ cord-005646-xhx9pzhj 1908 15 blood blood NN cord-005646-xhx9pzhj 1908 16 tests test NNS cord-005646-xhx9pzhj 1908 17 and and CC cord-005646-xhx9pzhj 1908 18 including include VBG cord-005646-xhx9pzhj 1908 19 chronic chronic JJ cord-005646-xhx9pzhj 1908 20 health health NN cord-005646-xhx9pzhj 1908 21 status status NN cord-005646-xhx9pzhj 1908 22 would would MD cord-005646-xhx9pzhj 1908 23 be be VB cord-005646-xhx9pzhj 1908 24 a a DT cord-005646-xhx9pzhj 1908 25 useful useful JJ cord-005646-xhx9pzhj 1908 26 tool tool NN cord-005646-xhx9pzhj 1908 27 . . . cord-005646-xhx9pzhj 1909 1 The the DT cord-005646-xhx9pzhj 1909 2 establishment establishment NN cord-005646-xhx9pzhj 1909 3 of of IN cord-005646-xhx9pzhj 1909 4 a a DT cord-005646-xhx9pzhj 1909 5 paediatric paediatric JJ cord-005646-xhx9pzhj 1909 6 intensive intensive JJ cord-005646-xhx9pzhj 1909 7 care care NN cord-005646-xhx9pzhj 1909 8 unit unit NN cord-005646-xhx9pzhj 1909 9 is be VBZ cord-005646-xhx9pzhj 1909 10 proposed propose VBN cord-005646-xhx9pzhj 1909 11 to to TO cord-005646-xhx9pzhj 1909 12 redress redress VB cord-005646-xhx9pzhj 1909 13 the the DT cord-005646-xhx9pzhj 1909 14 balance balance NN cord-005646-xhx9pzhj 1909 15 of of IN cord-005646-xhx9pzhj 1909 16 care care NN cord-005646-xhx9pzhj 1909 17 . . . cord-005646-xhx9pzhj 1910 1 To to TO cord-005646-xhx9pzhj 1910 2 assess assess VB cord-005646-xhx9pzhj 1910 3 the the DT cord-005646-xhx9pzhj 1910 4 performance performance NN cord-005646-xhx9pzhj 1910 5 of of IN cord-005646-xhx9pzhj 1910 6 the the DT cord-005646-xhx9pzhj 1910 7 Pediatric Pediatric NNP cord-005646-xhx9pzhj 1910 8 Intensive Intensive NNP cord-005646-xhx9pzhj 1910 9 Care Care NNP cord-005646-xhx9pzhj 1910 10 Unit Unit NNP cord-005646-xhx9pzhj 1910 11 of of IN cord-005646-xhx9pzhj 1910 12 Hospital Hospital NNP cord-005646-xhx9pzhj 1910 13 Dona Dona NNP cord-005646-xhx9pzhj 1910 14 Estef Estef NNP cord-005646-xhx9pzhj 1910 15 ~ ~ NFP cord-005646-xhx9pzhj 1910 16 nia nia NNP cord-005646-xhx9pzhj 1910 17 by by IN cord-005646-xhx9pzhj 1910 18 an an DT cord-005646-xhx9pzhj 1910 19 international international JJ cord-005646-xhx9pzhj 1910 20 standard standard JJ cord-005646-xhx9pzhj 1910 21 score score NN cord-005646-xhx9pzhj 1910 22 , , , cord-005646-xhx9pzhj 1910 23 the the DT cord-005646-xhx9pzhj 1910 24 authors author NNS cord-005646-xhx9pzhj 1910 25 did do VBD cord-005646-xhx9pzhj 1910 26 a a DT cord-005646-xhx9pzhj 1910 27 prospective prospective JJ cord-005646-xhx9pzhj 1910 28 study study NN cord-005646-xhx9pzhj 1910 29 of of IN cord-005646-xhx9pzhj 1910 30 1149 1149 CD cord-005646-xhx9pzhj 1910 31 consecutive consecutive JJ cord-005646-xhx9pzhj 1910 32 admissions admission NNS cord-005646-xhx9pzhj 1910 33 to to IN cord-005646-xhx9pzhj 1910 34 the the DT cord-005646-xhx9pzhj 1910 35 Unit Unit NNP cord-005646-xhx9pzhj 1910 36 during during IN cord-005646-xhx9pzhj 1910 37 a a DT cord-005646-xhx9pzhj 1910 38 period period NN cord-005646-xhx9pzhj 1910 39 of of IN cord-005646-xhx9pzhj 1910 40 29 29 CD cord-005646-xhx9pzhj 1910 41 months month NNS cord-005646-xhx9pzhj 1910 42 . . . cord-005646-xhx9pzhj 1911 1 Mean mean JJ cord-005646-xhx9pzhj 1911 2 age age NN cord-005646-xhx9pzhj 1911 3 was be VBD cord-005646-xhx9pzhj 1911 4 50.63 50.63 CD cord-005646-xhx9pzhj 1911 5 _ _ NN cord-005646-xhx9pzhj 1911 6 + + CC cord-005646-xhx9pzhj 1911 7 54.07 54.07 CD cord-005646-xhx9pzhj 1911 8 months month NNS cord-005646-xhx9pzhj 1911 9 ; ; : cord-005646-xhx9pzhj 1911 10 mean mean JJ cord-005646-xhx9pzhj 1911 11 lengh lengh NN cord-005646-xhx9pzhj 1911 12 of of IN cord-005646-xhx9pzhj 1911 13 stay stay NN cord-005646-xhx9pzhj 1911 14 was be VBD cord-005646-xhx9pzhj 1911 15 3.16 3.16 CD cord-005646-xhx9pzhj 1911 16 + + SYM cord-005646-xhx9pzhj 1911 17 5.59 5.59 CD cord-005646-xhx9pzhj 1911 18 days day NNS cord-005646-xhx9pzhj 1911 19 . . . cord-005646-xhx9pzhj 1912 1 The the DT cord-005646-xhx9pzhj 1912 2 effectiveness effectiveness NN cord-005646-xhx9pzhj 1912 3 and and CC cord-005646-xhx9pzhj 1912 4 efficiency efficiency NN cord-005646-xhx9pzhj 1912 5 were be VBD cord-005646-xhx9pzhj 1912 6 determined determine VBN cord-005646-xhx9pzhj 1912 7 by by IN cord-005646-xhx9pzhj 1912 8 the the DT cord-005646-xhx9pzhj 1912 9 admission admission NN cord-005646-xhx9pzhj 1912 10 PRISM prism NN cord-005646-xhx9pzhj 1912 11 . . . cord-005646-xhx9pzhj 1913 1 Admission admission NN cord-005646-xhx9pzhj 1913 2 efficiency efficiency NN cord-005646-xhx9pzhj 1913 3 was be VBD cord-005646-xhx9pzhj 1913 4 defined define VBN cord-005646-xhx9pzhj 1913 5 by by IN cord-005646-xhx9pzhj 1913 6 two two CD cord-005646-xhx9pzhj 1913 7 criteria criterion NNS cord-005646-xhx9pzhj 1913 8 : : : cord-005646-xhx9pzhj 1913 9 a a LS cord-005646-xhx9pzhj 1913 10 ) ) -RRB- cord-005646-xhx9pzhj 1913 11 mortality mortality NN cord-005646-xhx9pzhj 1913 12 risk risk NN cord-005646-xhx9pzhj 1913 13 > > XX cord-005646-xhx9pzhj 1913 14 1 1 CD cord-005646-xhx9pzhj 1913 15 % % NN cord-005646-xhx9pzhj 1913 16 or or CC cord-005646-xhx9pzhj 1913 17 b b NN cord-005646-xhx9pzhj 1913 18 ) ) -RRB- cord-005646-xhx9pzhj 1914 1 the the DT cord-005646-xhx9pzhj 1914 2 administration administration NN cord-005646-xhx9pzhj 1914 3 of of IN cord-005646-xhx9pzhj 1914 4 at at RB cord-005646-xhx9pzhj 1914 5 least least JJS cord-005646-xhx9pzhj 1914 6 one one CD cord-005646-xhx9pzhj 1914 7 Intensive Intensive NNP cord-005646-xhx9pzhj 1914 8 Care Care NNP cord-005646-xhx9pzhj 1914 9 Unit unit NN cord-005646-xhx9pzhj 1914 10 - - HYPH cord-005646-xhx9pzhj 1914 11 dependent dependent JJ cord-005646-xhx9pzhj 1914 12 therapy therapy NN cord-005646-xhx9pzhj 1914 13 . . . cord-005646-xhx9pzhj 1915 1 The the DT cord-005646-xhx9pzhj 1915 2 cumulative cumulative JJ cord-005646-xhx9pzhj 1915 3 observed observed JJ cord-005646-xhx9pzhj 1915 4 mortality mortality NN cord-005646-xhx9pzhj 1915 5 was be VBD cord-005646-xhx9pzhj 1915 6 5.57 5.57 CD cord-005646-xhx9pzhj 1915 7 % % NN cord-005646-xhx9pzhj 1915 8 and and CC cord-005646-xhx9pzhj 1915 9 the the DT cord-005646-xhx9pzhj 1915 10 expected expect VBN cord-005646-xhx9pzhj 1915 11 mortality mortality NN cord-005646-xhx9pzhj 1915 12 was be VBD cord-005646-xhx9pzhj 1915 13 5.97 5.97 CD cord-005646-xhx9pzhj 1915 14 % % NN cord-005646-xhx9pzhj 1915 15 , , , cord-005646-xhx9pzhj 1915 16 with with IN cord-005646-xhx9pzhj 1915 17 a a DT cord-005646-xhx9pzhj 1915 18 Standardized Standardized NNP cord-005646-xhx9pzhj 1915 19 Mortality Mortality NNP cord-005646-xhx9pzhj 1915 20 Ratio Ratio NNP cord-005646-xhx9pzhj 1915 21 ( ( -LRB- cord-005646-xhx9pzhj 1915 22 SMR SMR NNP cord-005646-xhx9pzhj 1915 23 ) ) -RRB- cord-005646-xhx9pzhj 1915 24 = = SYM cord-005646-xhx9pzhj 1915 25 0.933 0.933 CD cord-005646-xhx9pzhj 1915 26 . . . cord-005646-xhx9pzhj 1916 1 The the DT cord-005646-xhx9pzhj 1916 2 overall overall JJ cord-005646-xhx9pzhj 1916 3 performance performance NN cord-005646-xhx9pzhj 1916 4 of of IN cord-005646-xhx9pzhj 1916 5 the the DT cord-005646-xhx9pzhj 1916 6 PRISM PRISM NNP cord-005646-xhx9pzhj 1916 7 score score NN cord-005646-xhx9pzhj 1916 8 - - HYPH cord-005646-xhx9pzhj 1916 9 based base VBN cord-005646-xhx9pzhj 1916 10 predictive predictive JJ cord-005646-xhx9pzhj 1916 11 model model NN cord-005646-xhx9pzhj 1916 12 was be VBD cord-005646-xhx9pzhj 1916 13 found find VBN cord-005646-xhx9pzhj 1916 14 to to TO cord-005646-xhx9pzhj 1916 15 be be VB cord-005646-xhx9pzhj 1916 16 good good JJ cord-005646-xhx9pzhj 1917 1 ( ( -LRB- cord-005646-xhx9pzhj 1917 2 goodness goodness NN cord-005646-xhx9pzhj 1917 3 - - HYPH cord-005646-xhx9pzhj 1917 4 of of IN cord-005646-xhx9pzhj 1917 5 - - HYPH cord-005646-xhx9pzhj 1917 6 fit fit JJ cord-005646-xhx9pzhj 1917 7 test test NN cord-005646-xhx9pzhj 1917 8 x2 x2 NN cord-005646-xhx9pzhj 1917 9 [ [ -LRB- cord-005646-xhx9pzhj 1917 10 5 5 CD cord-005646-xhx9pzhj 1917 11 ] ] -RRB- cord-005646-xhx9pzhj 1917 12 = = SYM cord-005646-xhx9pzhj 1917 13 6.387;p=0.271 6.387;p=0.271 CD cord-005646-xhx9pzhj 1917 14 ) ) -RRB- cord-005646-xhx9pzhj 1917 15 . . . cord-005646-xhx9pzhj 1918 1 Of of IN cord-005646-xhx9pzhj 1918 2 1149 1149 CD cord-005646-xhx9pzhj 1918 3 patients patient NNS cord-005646-xhx9pzhj 1918 4 admitted admit VBN cord-005646-xhx9pzhj 1918 5 , , , cord-005646-xhx9pzhj 1918 6 combining combine VBG cord-005646-xhx9pzhj 1918 7 the the DT cord-005646-xhx9pzhj 1918 8 two two CD cord-005646-xhx9pzhj 1918 9 criteria criterion NNS cord-005646-xhx9pzhj 1918 10 ( ( -LRB- cord-005646-xhx9pzhj 1918 11 ICUdependent icudependent JJ cord-005646-xhx9pzhj 1918 12 therapy therapy NN cord-005646-xhx9pzhj 1918 13 and and CC cord-005646-xhx9pzhj 1918 14 mortality mortality NN cord-005646-xhx9pzhj 1918 15 risk risk NN cord-005646-xhx9pzhj 1918 16 ) ) -RRB- cord-005646-xhx9pzhj 1918 17 an an DT cord-005646-xhx9pzhj 1918 18 admission admission NN cord-005646-xhx9pzhj 1918 19 efficiency efficiency NN cord-005646-xhx9pzhj 1918 20 of of IN cord-005646-xhx9pzhj 1918 21 825 825 CD cord-005646-xhx9pzhj 1918 22 ( ( -LRB- cord-005646-xhx9pzhj 1918 23 71.8 71.8 CD cord-005646-xhx9pzhj 1918 24 % % NN cord-005646-xhx9pzhj 1918 25 ) ) -RRB- cord-005646-xhx9pzhj 1918 26 was be VBD cord-005646-xhx9pzhj 1918 27 found find VBN cord-005646-xhx9pzhj 1918 28 , , , cord-005646-xhx9pzhj 1918 29 equating equate VBG cord-005646-xhx9pzhj 1918 30 to to IN cord-005646-xhx9pzhj 1918 31 3263 3263 CD cord-005646-xhx9pzhj 1918 32 ( ( -LRB- cord-005646-xhx9pzhj 1918 33 89.94 89.94 CD cord-005646-xhx9pzhj 1918 34 % % NN cord-005646-xhx9pzhj 1918 35 ) ) -RRB- cord-005646-xhx9pzhj 1918 36 of of IN cord-005646-xhx9pzhj 1918 37 3628 3628 CD cord-005646-xhx9pzhj 1918 38 1CU 1cu CD cord-005646-xhx9pzhj 1918 39 days day NNS cord-005646-xhx9pzhj 1918 40 . . . cord-005646-xhx9pzhj 1919 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 1919 2 : : : cord-005646-xhx9pzhj 1920 1 In in IN cord-005646-xhx9pzhj 1920 2 our -PRON- PRP$ cord-005646-xhx9pzhj 1920 3 study study NN cord-005646-xhx9pzhj 1920 4 the the DT cord-005646-xhx9pzhj 1920 5 assessment assessment NN cord-005646-xhx9pzhj 1920 6 of of IN cord-005646-xhx9pzhj 1920 7 the the DT cord-005646-xhx9pzhj 1920 8 admission admission NN cord-005646-xhx9pzhj 1920 9 efficiency efficiency NN cord-005646-xhx9pzhj 1920 10 and and CC cord-005646-xhx9pzhj 1920 11 of of IN cord-005646-xhx9pzhj 1920 12 the the DT cord-005646-xhx9pzhj 1920 13 effectiveness effectiveness NN cord-005646-xhx9pzhj 1920 14 of of IN cord-005646-xhx9pzhj 1920 15 the the DT cord-005646-xhx9pzhj 1920 16 Unit Unit NNP cord-005646-xhx9pzhj 1920 17 was be VBD cord-005646-xhx9pzhj 1920 18 possible possible JJ cord-005646-xhx9pzhj 1920 19 by by IN cord-005646-xhx9pzhj 1920 20 using use VBG cord-005646-xhx9pzhj 1920 21 the the DT cord-005646-xhx9pzhj 1920 22 PRISM PRISM NNP cord-005646-xhx9pzhj 1920 23 score score NN cord-005646-xhx9pzhj 1920 24 of of IN cord-005646-xhx9pzhj 1920 25 admission admission NN cord-005646-xhx9pzhj 1920 26 . . . cord-005646-xhx9pzhj 1921 1 There there EX cord-005646-xhx9pzhj 1921 2 was be VBD cord-005646-xhx9pzhj 1921 3 no no DT cord-005646-xhx9pzhj 1921 4 significant significant JJ cord-005646-xhx9pzhj 1921 5 difference difference NN cord-005646-xhx9pzhj 1921 6 between between IN cord-005646-xhx9pzhj 1921 7 mean mean JJ cord-005646-xhx9pzhj 1921 8 values value NNS cord-005646-xhx9pzhj 1921 9 for for IN cord-005646-xhx9pzhj 1921 10 OTISS OTISS NNP cord-005646-xhx9pzhj 1921 11 and and CC cord-005646-xhx9pzhj 1921 12 NTISS)in ntiss)in NN cord-005646-xhx9pzhj 1922 1 Level level NN cord-005646-xhx9pzhj 1922 2 l l NN cord-005646-xhx9pzhj 1922 3 patients patient NNS cord-005646-xhx9pzhj 1922 4 ( ( -LRB- cord-005646-xhx9pzhj 1922 5 P=0.12 p=0.12 NN cord-005646-xhx9pzhj 1922 6 paired pair VBD cord-005646-xhx9pzhj 1922 7 t t NN cord-005646-xhx9pzhj 1922 8 - - HYPH cord-005646-xhx9pzhj 1922 9 test).For test).For NNP cord-005646-xhx9pzhj 1922 10 level level NN cord-005646-xhx9pzhj 1922 11 2 2 CD cord-005646-xhx9pzhj 1922 12 and and CC cord-005646-xhx9pzhj 1922 13 3 3 CD cord-005646-xhx9pzhj 1922 14 patients patient NNS cord-005646-xhx9pzhj 1923 1 mean mean JJ cord-005646-xhx9pzhj 1923 2 value value NN cord-005646-xhx9pzhj 1923 3 of of IN cord-005646-xhx9pzhj 1923 4 NTISS NTISS NNP cord-005646-xhx9pzhj 1923 5 was be VBD cord-005646-xhx9pzhj 1923 6 greater great JJR cord-005646-xhx9pzhj 1923 7 than than IN cord-005646-xhx9pzhj 1923 8 OTISS OTISS NNP cord-005646-xhx9pzhj 1924 1 ( ( -LRB- cord-005646-xhx9pzhj 1924 2 P<0.0001 p<0.0001 JJ cord-005646-xhx9pzhj 1924 3 ) ) -RRB- cord-005646-xhx9pzhj 1924 4 . . . cord-005646-xhx9pzhj 1925 1 There there EX cord-005646-xhx9pzhj 1925 2 was be VBD cord-005646-xhx9pzhj 1925 3 a a DT cord-005646-xhx9pzhj 1925 4 significant significant JJ cord-005646-xhx9pzhj 1925 5 correlation correlation NN cord-005646-xhx9pzhj 1925 6 between between IN cord-005646-xhx9pzhj 1925 7 levels level NNS cord-005646-xhx9pzhj 1925 8 using use VBG cord-005646-xhx9pzhj 1925 9 either either CC cord-005646-xhx9pzhj 1925 10 NTISS NTISS NNP cord-005646-xhx9pzhj 1925 11 or or CC cord-005646-xhx9pzhj 1925 12 OTISS OTISS NNP cord-005646-xhx9pzhj 1925 13 ( ( -LRB- cord-005646-xhx9pzhj 1925 14 mean mean VB cord-005646-xhx9pzhj 1925 15 difference difference NN cord-005646-xhx9pzhj 1925 16 Level level NN cord-005646-xhx9pzhj 1925 17 1 1 CD cord-005646-xhx9pzhj 1925 18 and and CC cord-005646-xhx9pzhj 1925 19 2 2 CD cord-005646-xhx9pzhj 1925 20 , , , cord-005646-xhx9pzhj 1925 21 Level level NN cord-005646-xhx9pzhj 1925 22 2 2 CD cord-005646-xhx9pzhj 1925 23 and and CC cord-005646-xhx9pzhj 1925 24 3 3 CD cord-005646-xhx9pzhj 1925 25 , , , cord-005646-xhx9pzhj 1925 26 ( ( -LRB- cord-005646-xhx9pzhj 1925 27 P p NN cord-005646-xhx9pzhj 1925 28 < < XX cord-005646-xhx9pzhj 1925 29 o.oool o.oool ADD cord-005646-xhx9pzhj 1925 30 ) ) -RRB- cord-005646-xhx9pzhj 1925 31 . . . cord-005646-xhx9pzhj 1926 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 1926 2 : : : cord-005646-xhx9pzhj 1927 1 A a DT cord-005646-xhx9pzhj 1927 2 new new JJ cord-005646-xhx9pzhj 1927 3 TISS TISS NNP cord-005646-xhx9pzhj 1927 4 has have VBZ cord-005646-xhx9pzhj 1927 5 been be VBN cord-005646-xhx9pzhj 1927 6 developed develop VBN cord-005646-xhx9pzhj 1927 7 and and CC cord-005646-xhx9pzhj 1927 8 used use VBN cord-005646-xhx9pzhj 1927 9 in in IN cord-005646-xhx9pzhj 1927 10 a a DT cord-005646-xhx9pzhj 1927 11 PICU PICU NNP cord-005646-xhx9pzhj 1927 12 . . . cord-005646-xhx9pzhj 1928 1 Nurses nurse NNS cord-005646-xhx9pzhj 1928 2 were be VBD cord-005646-xhx9pzhj 1928 3 able able JJ cord-005646-xhx9pzhj 1928 4 to to TO cord-005646-xhx9pzhj 1928 5 accurately accurately RB cord-005646-xhx9pzhj 1928 6 score score VB cord-005646-xhx9pzhj 1928 7 the the DT cord-005646-xhx9pzhj 1928 8 interventions intervention NNS cord-005646-xhx9pzhj 1928 9 on on IN cord-005646-xhx9pzhj 1928 10 their -PRON- PRP$ cord-005646-xhx9pzhj 1928 11 shift shift NN cord-005646-xhx9pzhj 1928 12 . . . cord-005646-xhx9pzhj 1929 1 The the DT cord-005646-xhx9pzhj 1929 2 assignment assignment NN cord-005646-xhx9pzhj 1929 3 of of IN cord-005646-xhx9pzhj 1929 4 patients patient NNS cord-005646-xhx9pzhj 1929 5 to to TO cord-005646-xhx9pzhj 1929 6 intensive intensive JJ cord-005646-xhx9pzhj 1929 7 care care NN cord-005646-xhx9pzhj 1929 8 levels level NNS cord-005646-xhx9pzhj 1929 9 correlates correlate VBZ cord-005646-xhx9pzhj 1929 10 with with IN cord-005646-xhx9pzhj 1929 11 TISS TISS NNP cord-005646-xhx9pzhj 1929 12 values value NNS cord-005646-xhx9pzhj 1929 13 allowing allow VBG cord-005646-xhx9pzhj 1929 14 a a DT cord-005646-xhx9pzhj 1929 15 quantitative quantitative JJ cord-005646-xhx9pzhj 1929 16 measure measure NN cord-005646-xhx9pzhj 1929 17 of of IN cord-005646-xhx9pzhj 1929 18 severity severity NN cord-005646-xhx9pzhj 1929 19 . . . cord-005646-xhx9pzhj 1930 1 Objective objective NN cord-005646-xhx9pzhj 1930 2 : : : cord-005646-xhx9pzhj 1930 3 to to TO cord-005646-xhx9pzhj 1930 4 compare compare VB cord-005646-xhx9pzhj 1930 5 the the DT cord-005646-xhx9pzhj 1930 6 rate rate NN cord-005646-xhx9pzhj 1930 7 of of IN cord-005646-xhx9pzhj 1930 8 cerebral cerebral JJ cord-005646-xhx9pzhj 1930 9 palsy palsy NN cord-005646-xhx9pzhj 1930 10 ( ( -LRB- cord-005646-xhx9pzhj 1930 11 CP CP NNP cord-005646-xhx9pzhj 1930 12 ) ) -RRB- cord-005646-xhx9pzhj 1930 13 between between IN cord-005646-xhx9pzhj 1930 14 monochorionic monochorionic JJ cord-005646-xhx9pzhj 1930 15 - - HYPH cord-005646-xhx9pzhj 1930 16 twins twin NNS cord-005646-xhx9pzhj 1930 17 , , , cord-005646-xhx9pzhj 1930 18 dichorionic dichorionic NN cord-005646-xhx9pzhj 1930 19 - - HYPH cord-005646-xhx9pzhj 1930 20 twins twin NNS cord-005646-xhx9pzhj 1930 21 and and CC cord-005646-xhx9pzhj 1930 22 singletons singleton NNS cord-005646-xhx9pzhj 1930 23 born bear VBN cord-005646-xhx9pzhj 1930 24 at at IN cord-005646-xhx9pzhj 1930 25 25 25 CD cord-005646-xhx9pzhj 1930 26 to to TO cord-005646-xhx9pzhj 1930 27 32 32 CD cord-005646-xhx9pzhj 1930 28 weeks week NNS cord-005646-xhx9pzhj 1930 29 ' ' POS cord-005646-xhx9pzhj 1930 30 gestation gestation NN cord-005646-xhx9pzhj 1930 31 . . . cord-005646-xhx9pzhj 1931 1 Design design NN cord-005646-xhx9pzhj 1931 2 : : : cord-005646-xhx9pzhj 1931 3 two two CD cord-005646-xhx9pzhj 1931 4 - - HYPH cord-005646-xhx9pzhj 1931 5 year year NN cord-005646-xhx9pzhj 1931 6 prospective prospective JJ cord-005646-xhx9pzhj 1931 7 cohort cohort NN cord-005646-xhx9pzhj 1931 8 study study NN cord-005646-xhx9pzhj 1931 9 . . . cord-005646-xhx9pzhj 1932 1 Setting set VBG cord-005646-xhx9pzhj 1932 2 : : : cord-005646-xhx9pzhj 1932 3 geographically geographically RB cord-005646-xhx9pzhj 1932 4 defined define VBN cord-005646-xhx9pzhj 1932 5 study study NN cord-005646-xhx9pzhj 1932 6 ( ( -LRB- cord-005646-xhx9pzhj 1932 7 region region NN cord-005646-xhx9pzhj 1932 8 of of IN cord-005646-xhx9pzhj 1932 9 Franche Franche NNP cord-005646-xhx9pzhj 1932 10 - - HYPH cord-005646-xhx9pzhj 1932 11 Comt~. Comt~. NNP cord-005646-xhx9pzhj 1932 12 , , , cord-005646-xhx9pzhj 1932 13 FRANCE FRANCE NNP cord-005646-xhx9pzhj 1932 14 ) ) -RRB- cord-005646-xhx9pzhj 1932 15 . . . cord-005646-xhx9pzhj 1933 1 Main main JJ cord-005646-xhx9pzhj 1933 2 outcome outcome NN cord-005646-xhx9pzhj 1933 3 measures measure NNS cord-005646-xhx9pzhj 1933 4 : : : cord-005646-xhx9pzhj 1933 5 type type NN cord-005646-xhx9pzhj 1933 6 of of IN cord-005646-xhx9pzhj 1933 7 plasentation plasentation NN cord-005646-xhx9pzhj 1933 8 was be VBD cord-005646-xhx9pzhj 1933 9 obtained obtain VBN cord-005646-xhx9pzhj 1933 10 by by IN cord-005646-xhx9pzhj 1933 11 anatomopathological anatomopathological NNP cord-005646-xhx9pzhj 1933 12 , , , cord-005646-xhx9pzhj 1933 13 or or CC cord-005646-xhx9pzhj 1933 14 macroscopic macroscopic JJ cord-005646-xhx9pzhj 1933 15 examination examination NN cord-005646-xhx9pzhj 1933 16 of of IN cord-005646-xhx9pzhj 1933 17 placenta placenta NN cord-005646-xhx9pzhj 1933 18 and and CC cord-005646-xhx9pzhj 1933 19 comparison comparison NN cord-005646-xhx9pzhj 1933 20 of of IN cord-005646-xhx9pzhj 1933 21 6 6 CD cord-005646-xhx9pzhj 1933 22 twins twin NNS cord-005646-xhx9pzhj 1933 23 ' ' POS cord-005646-xhx9pzhj 1933 24 blood blood NN cord-005646-xhx9pzhj 1933 25 - - HYPH cord-005646-xhx9pzhj 1933 26 groups group NNS cord-005646-xhx9pzhj 1933 27 . . . cord-005646-xhx9pzhj 1934 1 Neurological neurological JJ cord-005646-xhx9pzhj 1934 2 assessment assessment NN cord-005646-xhx9pzhj 1934 3 was be VBD cord-005646-xhx9pzhj 1934 4 performed perform VBN cord-005646-xhx9pzhj 1934 5 at at IN cord-005646-xhx9pzhj 1934 6 two two CD cord-005646-xhx9pzhj 1934 7 years year NNS cord-005646-xhx9pzhj 1934 8 of of IN cord-005646-xhx9pzhj 1934 9 age age NN cord-005646-xhx9pzhj 1934 10 ( ( -LRB- cord-005646-xhx9pzhj 1934 11 uncorrected uncorrected JJ cord-005646-xhx9pzhj 1934 12 for for IN cord-005646-xhx9pzhj 1934 13 gestational gestational JJ cord-005646-xhx9pzhj 1934 14 age age NN cord-005646-xhx9pzhj 1934 15 ) ) -RRB- cord-005646-xhx9pzhj 1934 16 by by IN cord-005646-xhx9pzhj 1934 17 family family NN cord-005646-xhx9pzhj 1934 18 doctor doctor NN cord-005646-xhx9pzhj 1934 19 ( ( -LRB- cord-005646-xhx9pzhj 1934 20 pediatrician pediatrician NN cord-005646-xhx9pzhj 1934 21 or or CC cord-005646-xhx9pzhj 1934 22 physician physician NN cord-005646-xhx9pzhj 1934 23 ) ) -RRB- cord-005646-xhx9pzhj 1934 24 , , , cord-005646-xhx9pzhj 1934 25 or or CC cord-005646-xhx9pzhj 1934 26 neonatologist neonatologist NN cord-005646-xhx9pzhj 1934 27 of of IN cord-005646-xhx9pzhj 1934 28 the the DT cord-005646-xhx9pzhj 1934 29 ICU ICU NNP cord-005646-xhx9pzhj 1934 30 at at IN cord-005646-xhx9pzhj 1934 31 tertiary tertiary JJ cord-005646-xhx9pzhj 1934 32 center center NN cord-005646-xhx9pzhj 1934 33 . . . cord-005646-xhx9pzhj 1935 1 Sample sample NN cord-005646-xhx9pzhj 1935 2 : : : cord-005646-xhx9pzhj 1935 3 167 167 CD cord-005646-xhx9pzhj 1935 4 of of IN cord-005646-xhx9pzhj 1935 5 17I 17i CD cord-005646-xhx9pzhj 1935 6 survivors survivor NNS cord-005646-xhx9pzhj 1935 7 aged age VBN cord-005646-xhx9pzhj 1935 8 of of IN cord-005646-xhx9pzhj 1935 9 two two CD cord-005646-xhx9pzhj 1935 10 years year NNS cord-005646-xhx9pzhj 1935 11 ( ( -LRB- cord-005646-xhx9pzhj 1935 12 98 98 CD cord-005646-xhx9pzhj 1935 13 % % NN cord-005646-xhx9pzhj 1935 14 follow follow NN cord-005646-xhx9pzhj 1935 15 - - HYPH cord-005646-xhx9pzhj 1935 16 up up NN cord-005646-xhx9pzhj 1935 17 rate rate NN cord-005646-xhx9pzhj 1935 18 ) ) -RRB- cord-005646-xhx9pzhj 1935 19 , , , cord-005646-xhx9pzhj 1935 20 born bear VBN cord-005646-xhx9pzhj 1935 21 between between IN cord-005646-xhx9pzhj 1935 22 09/30/90 09/30/90 CD cord-005646-xhx9pzhj 1935 23 and and CC cord-005646-xhx9pzhj 1935 24 10/01192 10/01192 CD cord-005646-xhx9pzhj 1935 25 . . . cord-005646-xhx9pzhj 1936 1 Triplets triplet NNS cord-005646-xhx9pzhj 1936 2 and and CC cord-005646-xhx9pzhj 1936 3 chromosomic chromosomic JJ cord-005646-xhx9pzhj 1936 4 malformation malformation NN cord-005646-xhx9pzhj 1936 5 were be VBD cord-005646-xhx9pzhj 1936 6 non non JJ cord-005646-xhx9pzhj 1936 7 included include VBN cord-005646-xhx9pzhj 1936 8 . . . cord-005646-xhx9pzhj 1937 1 Results result NNS cord-005646-xhx9pzhj 1937 2 : : : cord-005646-xhx9pzhj 1938 1 Thirteen thirteen CD cord-005646-xhx9pzhj 1938 2 ( ( -LRB- cord-005646-xhx9pzhj 1938 3 11 11 CD cord-005646-xhx9pzhj 1938 4 % % NN cord-005646-xhx9pzhj 1938 5 ) ) -RRB- cord-005646-xhx9pzhj 1938 6 of of IN cord-005646-xhx9pzhj 1938 7 the the DT cord-005646-xhx9pzhj 1938 8 119 119 CD cord-005646-xhx9pzhj 1938 9 singletons singleton NNS cord-005646-xhx9pzhj 1938 10 had have VBD cord-005646-xhx9pzhj 1938 11 CP.vs cp.v VBN cord-005646-xhx9pzhj 1939 1 3/29 3/29 CD cord-005646-xhx9pzhj 1939 2 ( ( -LRB- cord-005646-xhx9pzhj 1939 3 10 10 CD cord-005646-xhx9pzhj 1939 4 % % NN cord-005646-xhx9pzhj 1939 5 ) ) -RRB- cord-005646-xhx9pzhj 1939 6 of of IN cord-005646-xhx9pzhj 1939 7 dichorionic dichorionic JJ cord-005646-xhx9pzhj 1939 8 twins twin NNS cord-005646-xhx9pzhj 1939 9 and and CC cord-005646-xhx9pzhj 1939 10 6/19 6/19 CD cord-005646-xhx9pzhj 1939 11 ( ( -LRB- cord-005646-xhx9pzhj 1939 12 32 32 CD cord-005646-xhx9pzhj 1939 13 % % NN cord-005646-xhx9pzhj 1939 14 ) ) -RRB- cord-005646-xhx9pzhj 1939 15 of of IN cord-005646-xhx9pzhj 1939 16 monochorionic monochorionic JJ cord-005646-xhx9pzhj 1939 17 twins twin NNS cord-005646-xhx9pzhj 1939 18 ( ( -LRB- cord-005646-xhx9pzhj 1939 19 p=0.04 p=0.04 NNP cord-005646-xhx9pzhj 1939 20 ) ) -RRB- cord-005646-xhx9pzhj 1939 21 . . . cord-005646-xhx9pzhj 1940 1 Four four CD cord-005646-xhx9pzhj 1940 2 of of IN cord-005646-xhx9pzhj 1940 3 the the DT cord-005646-xhx9pzhj 1940 4 19 19 CD cord-005646-xhx9pzhj 1940 5 monochorionic monochorionic JJ cord-005646-xhx9pzhj 1940 6 twins twin NNS cord-005646-xhx9pzhj 1940 7 ( ( -LRB- cord-005646-xhx9pzhj 1940 8 21 21 CD cord-005646-xhx9pzhj 1940 9 % % NN cord-005646-xhx9pzhj 1940 10 ) ) -RRB- cord-005646-xhx9pzhj 1940 11 , , , cord-005646-xhx9pzhj 1940 12 2/29 2/29 CD cord-005646-xhx9pzhj 1940 13 dichorionic dichorionic JJ cord-005646-xhx9pzhj 1940 14 twins twin NNS cord-005646-xhx9pzhj 1940 15 ( ( -LRB- cord-005646-xhx9pzhj 1940 16 10 10 CD cord-005646-xhx9pzhj 1940 17 % % NN cord-005646-xhx9pzhj 1940 18 ) ) -RRB- cord-005646-xhx9pzhj 1940 19 and and CC cord-005646-xhx9pzhj 1940 20 4/119 4/119 CD cord-005646-xhx9pzhj 1940 21 ( ( -LRB- cord-005646-xhx9pzhj 1940 22 3 3 CD cord-005646-xhx9pzhj 1940 23 % % NN cord-005646-xhx9pzhj 1940 24 ) ) -RRB- cord-005646-xhx9pzhj 1941 1 Nngletons nngleton NNS cord-005646-xhx9pzhj 1941 2 suffer suffer VBP cord-005646-xhx9pzhj 1941 3 from from IN cord-005646-xhx9pzhj 1941 4 quadriplegia quadriplegia NNP cord-005646-xhx9pzhj 1941 5 ( ( -LRB- cord-005646-xhx9pzhj 1941 6 p<0.01).In p<0.01).in VB cord-005646-xhx9pzhj 1941 7 a a DT cord-005646-xhx9pzhj 1941 8 multivariate multivariate JJ cord-005646-xhx9pzhj 1941 9 approach approach NN cord-005646-xhx9pzhj 1941 10 , , , cord-005646-xhx9pzhj 1941 11 monochorionic monochorionic JJ cord-005646-xhx9pzhj 1941 12 twin twin JJ cord-005646-xhx9pzhj 1941 13 placentation placentation NN cord-005646-xhx9pzhj 1941 14 was be VBD cord-005646-xhx9pzhj 1941 15 the the DT cord-005646-xhx9pzhj 1941 16 strongest strong JJS cord-005646-xhx9pzhj 1941 17 risk risk NN cord-005646-xhx9pzhj 1941 18 - - HYPH cord-005646-xhx9pzhj 1941 19 factor factor NN cord-005646-xhx9pzhj 1941 20 of of IN cord-005646-xhx9pzhj 1941 21 cerebral cerebral JJ cord-005646-xhx9pzhj 1941 22 palsy palsy NN cord-005646-xhx9pzhj 1941 23 ( ( -LRB- cord-005646-xhx9pzhj 1941 24 OR=9.7 or=9.7 NN cord-005646-xhx9pzhj 1941 25 , , , cord-005646-xhx9pzhj 1941 26 IC IC NNP cord-005646-xhx9pzhj 1941 27 95 95 CD cord-005646-xhx9pzhj 1941 28 % % NN cord-005646-xhx9pzhj 1941 29 = = SYM cord-005646-xhx9pzhj 1941 30 2A-39 2a-39 CD cord-005646-xhx9pzhj 1941 31 , , , cord-005646-xhx9pzhj 1941 32 p<6.01 p<6.01 CD cord-005646-xhx9pzhj 1941 33 ) ) -RRB- cord-005646-xhx9pzhj 1941 34 . . . cord-005646-xhx9pzhj 1942 1 Others other NNS cord-005646-xhx9pzhj 1942 2 risk risk NN cord-005646-xhx9pzhj 1942 3 - - HYPH cord-005646-xhx9pzhj 1942 4 factors factor NNS cord-005646-xhx9pzhj 1942 5 of of IN cord-005646-xhx9pzhj 1942 6 CP CP NNP cord-005646-xhx9pzhj 1942 7 were be VBD cord-005646-xhx9pzhj 1942 8 : : : cord-005646-xhx9pzhj 1942 9 lack lack NN cord-005646-xhx9pzhj 1942 10 of of IN cord-005646-xhx9pzhj 1942 11 father father NN cord-005646-xhx9pzhj 1942 12 's 's POS cord-005646-xhx9pzhj 1942 13 profession profession NN cord-005646-xhx9pzhj 1942 14 ( ( -LRB- cord-005646-xhx9pzhj 1942 15 OR or CC cord-005646-xhx9pzhj 1942 16 11 11 CD cord-005646-xhx9pzhj 1942 17 , , , cord-005646-xhx9pzhj 1942 18 p<0 p<0 NNP cord-005646-xhx9pzhj 1942 19 .03 .03 NFP cord-005646-xhx9pzhj 1942 20 ) ) -RRB- cord-005646-xhx9pzhj 1942 21 , , , cord-005646-xhx9pzhj 1942 22 maternal maternal JJ cord-005646-xhx9pzhj 1942 23 antecedent antecedent NN cord-005646-xhx9pzhj 1942 24 of of IN cord-005646-xhx9pzhj 1942 25 abortion abortion NN cord-005646-xhx9pzhj 1942 26 ( ( -LRB- cord-005646-xhx9pzhj 1942 27 OR OR NNP cord-005646-xhx9pzhj 1942 28 3.2 3.2 CD cord-005646-xhx9pzhj 1942 29 , , , cord-005646-xhx9pzhj 1942 30 1 1 CD cord-005646-xhx9pzhj 1942 31 - - SYM cord-005646-xhx9pzhj 1942 32 10 10 CD cord-005646-xhx9pzhj 1942 33 , , , cord-005646-xhx9pzhj 1942 34 p<0.04 p<0.04 NN cord-005646-xhx9pzhj 1942 35 ) ) -RRB- cord-005646-xhx9pzhj 1942 36 , , , cord-005646-xhx9pzhj 1942 37 vaginal vaginal JJ cord-005646-xhx9pzhj 1942 38 delivery delivery NN cord-005646-xhx9pzhj 1942 39 ( ( -LRB- cord-005646-xhx9pzhj 1942 40 OR or CC cord-005646-xhx9pzhj 1942 41 3.4 3.4 CD cord-005646-xhx9pzhj 1942 42 , , , cord-005646-xhx9pzhj 1942 43 1 1 CD cord-005646-xhx9pzhj 1942 44 - - SYM cord-005646-xhx9pzhj 1942 45 11 11 CD cord-005646-xhx9pzhj 1942 46 , , , cord-005646-xhx9pzhj 1942 47 p<0.03 p<0.03 NNP cord-005646-xhx9pzhj 1942 48 ) ) -RRB- cord-005646-xhx9pzhj 1942 49 , , , cord-005646-xhx9pzhj 1942 50 hyaline hyaline JJ cord-005646-xhx9pzhj 1942 51 membrane membrane NN cord-005646-xhx9pzhj 1942 52 disease disease NN cord-005646-xhx9pzhj 1942 53 ( ( -LRB- cord-005646-xhx9pzhj 1942 54 OR or CC cord-005646-xhx9pzhj 1942 55 3.4 3.4 CD cord-005646-xhx9pzhj 1942 56 , , , cord-005646-xhx9pzhj 1942 57 1.2-t0 1.2-t0 CD cord-005646-xhx9pzhj 1942 58 , , , cord-005646-xhx9pzhj 1942 59 ~0.02 ~0.02 NFP cord-005646-xhx9pzhj 1942 60 ) ) -RRB- cord-005646-xhx9pzhj 1942 61 . . . cord-005646-xhx9pzhj 1943 1 Discussion discussion NN cord-005646-xhx9pzhj 1943 2 : : : cord-005646-xhx9pzhj 1944 1 this this DT cord-005646-xhx9pzhj 1944 2 is be VBZ cord-005646-xhx9pzhj 1944 3 the the DT cord-005646-xhx9pzhj 1944 4 first first JJ cord-005646-xhx9pzhj 1944 5 population population NN cord-005646-xhx9pzhj 1944 6 - - HYPH cord-005646-xhx9pzhj 1944 7 based base VBN cord-005646-xhx9pzhj 1944 8 study study NN cord-005646-xhx9pzhj 1944 9 to to IN cord-005646-xhx9pzhj 1944 10 uplight uplight VB cord-005646-xhx9pzhj 1944 11 the the DT cord-005646-xhx9pzhj 1944 12 role role NN cord-005646-xhx9pzhj 1944 13 of of IN cord-005646-xhx9pzhj 1944 14 monochorial monochorial JJ cord-005646-xhx9pzhj 1944 15 twin twin JJ cord-005646-xhx9pzhj 1944 16 - - HYPH cord-005646-xhx9pzhj 1944 17 placentation placentation NN cord-005646-xhx9pzhj 1944 18 as as IN cord-005646-xhx9pzhj 1944 19 a a DT cord-005646-xhx9pzhj 1944 20 strong strong JJ cord-005646-xhx9pzhj 1944 21 risk risk NN cord-005646-xhx9pzhj 1944 22 factor factor NN cord-005646-xhx9pzhj 1944 23 of of IN cord-005646-xhx9pzhj 1944 24 CP CP NNP cord-005646-xhx9pzhj 1944 25 for for IN cord-005646-xhx9pzhj 1944 26 premature premature JJ cord-005646-xhx9pzhj 1944 27 infants infant NNS cord-005646-xhx9pzhj 1944 28 . . . cord-005646-xhx9pzhj 1945 1 CP CP NNP cord-005646-xhx9pzhj 1945 2 is be VBZ cord-005646-xhx9pzhj 1945 3 more more RBR cord-005646-xhx9pzhj 1945 4 severe severe JJ cord-005646-xhx9pzhj 1945 5 in in IN cord-005646-xhx9pzhj 1945 6 monochodonic monochodonic JJ cord-005646-xhx9pzhj 1945 7 twins twin NNS cord-005646-xhx9pzhj 1945 8 than than IN cord-005646-xhx9pzhj 1945 9 in in IN cord-005646-xhx9pzhj 1945 10 other other JJ cord-005646-xhx9pzhj 1945 11 infants infant NNS cord-005646-xhx9pzhj 1945 12 . . . cord-005646-xhx9pzhj 1946 1 Mecanism mecanism NN cord-005646-xhx9pzhj 1946 2 of of IN cord-005646-xhx9pzhj 1946 3 cerebraT cerebraT NNP cord-005646-xhx9pzhj 1946 4 deficiency deficiency NN cord-005646-xhx9pzhj 1946 5 is be VBZ cord-005646-xhx9pzhj 1946 6 not not RB cord-005646-xhx9pzhj 1946 7 clear clear JJ cord-005646-xhx9pzhj 1946 8 since since IN cord-005646-xhx9pzhj 1946 9 none none NN cord-005646-xhx9pzhj 1946 10 of of IN cord-005646-xhx9pzhj 1946 11 our -PRON- PRP$ cord-005646-xhx9pzhj 1946 12 infants infant NNS cord-005646-xhx9pzhj 1946 13 with with IN cord-005646-xhx9pzhj 1946 14 CP CP NNP cord-005646-xhx9pzhj 1946 15 was be VBD cord-005646-xhx9pzhj 1946 16 survivor survivor NN cord-005646-xhx9pzhj 1946 17 of of IN cord-005646-xhx9pzhj 1946 18 an an DT cord-005646-xhx9pzhj 1946 19 in in IN cord-005646-xhx9pzhj 1946 20 utero utero NNP cord-005646-xhx9pzhj 1946 21 cotwin cotwin NNP cord-005646-xhx9pzhj 1946 22 's 's POS cord-005646-xhx9pzhj 1946 23 death death NN cord-005646-xhx9pzhj 1946 24 , , , cord-005646-xhx9pzhj 1946 25 and and CC cord-005646-xhx9pzhj 1946 26 none none NN cord-005646-xhx9pzhj 1946 27 of of IN cord-005646-xhx9pzhj 1946 28 these these DT cord-005646-xhx9pzhj 1946 29 infants infant NNS cord-005646-xhx9pzhj 1946 30 was be VBD cord-005646-xhx9pzhj 1946 31 exposed expose VBN cord-005646-xhx9pzhj 1946 32 to to IN cord-005646-xhx9pzhj 1946 33 twin twin NN cord-005646-xhx9pzhj 1946 34 to to IN cord-005646-xhx9pzhj 1946 35 twin twin JJ cord-005646-xhx9pzhj 1946 36 transfusion transfusion NN cord-005646-xhx9pzhj 1946 37 syndrome syndrome NN cord-005646-xhx9pzhj 1946 38 . . . cord-005646-xhx9pzhj 1947 1 Were be VBD cord-005646-xhx9pzhj 1947 2 these these DT cord-005646-xhx9pzhj 1947 3 monochorionic monochorionic JJ cord-005646-xhx9pzhj 1947 4 - - HYPH cord-005646-xhx9pzhj 1947 5 twins twin NNS cord-005646-xhx9pzhj 1947 6 affected affect VBN cord-005646-xhx9pzhj 1947 7 by by IN cord-005646-xhx9pzhj 1947 8 an an DT cord-005646-xhx9pzhj 1947 9 undiagnosed undiagnosed JJ cord-005646-xhx9pzhj 1947 10 neurological neurological JJ cord-005646-xhx9pzhj 1947 11 structural structural JJ cord-005646-xhx9pzhj 1947 12 defect defect NN cord-005646-xhx9pzhj 1947 13 that that WDT cord-005646-xhx9pzhj 1947 14 could could MD cord-005646-xhx9pzhj 1947 15 lead lead VB cord-005646-xhx9pzhj 1947 16 both both DT cord-005646-xhx9pzhj 1947 17 to to IN cord-005646-xhx9pzhj 1947 18 prematurity prematurity NN cord-005646-xhx9pzhj 1947 19 and and CC cord-005646-xhx9pzhj 1947 20 handicap handicap NN cord-005646-xhx9pzhj 1947 21 remains remain VBZ cord-005646-xhx9pzhj 1947 22 an an DT cord-005646-xhx9pzhj 1947 23 open open JJ cord-005646-xhx9pzhj 1947 24 question question NN cord-005646-xhx9pzhj 1947 25 , , , cord-005646-xhx9pzhj 1947 26 A a DT cord-005646-xhx9pzhj 1947 27 vital vital JJ cord-005646-xhx9pzhj 1947 28 role role NN cord-005646-xhx9pzhj 1947 29 of of IN cord-005646-xhx9pzhj 1947 30 the the DT cord-005646-xhx9pzhj 1947 31 intensivist intensivist NN cord-005646-xhx9pzhj 1947 32 is be VBZ cord-005646-xhx9pzhj 1947 33 to to TO cord-005646-xhx9pzhj 1947 34 ensure ensure VB cord-005646-xhx9pzhj 1947 35 that that IN cord-005646-xhx9pzhj 1947 36 knowledge knowledge NN cord-005646-xhx9pzhj 1947 37 and and CC cord-005646-xhx9pzhj 1947 38 practice practice NN cord-005646-xhx9pzhj 1947 39 are be VBP cord-005646-xhx9pzhj 1947 40 imparted impart VBN cord-005646-xhx9pzhj 1947 41 to to IN cord-005646-xhx9pzhj 1947 42 trainees trainee NNS cord-005646-xhx9pzhj 1947 43 in in IN cord-005646-xhx9pzhj 1947 44 the the DT cord-005646-xhx9pzhj 1947 45 ICU ICU NNP cord-005646-xhx9pzhj 1947 46 so so IN cord-005646-xhx9pzhj 1947 47 that that IN cord-005646-xhx9pzhj 1947 48 patients patient NNS cord-005646-xhx9pzhj 1947 49 receive receive VBP cord-005646-xhx9pzhj 1947 50 optimal optimal JJ cord-005646-xhx9pzhj 1947 51 care care NN cord-005646-xhx9pzhj 1947 52 . . . cord-005646-xhx9pzhj 1948 1 Teaching teach VBG cord-005646-xhx9pzhj 1948 2 effectiveness effectiveness NN cord-005646-xhx9pzhj 1948 3 varies vary VBZ cord-005646-xhx9pzhj 1948 4 widely widely RB cord-005646-xhx9pzhj 1948 5 leaving leave VBG cord-005646-xhx9pzhj 1948 6 gaps gap NNS cord-005646-xhx9pzhj 1948 7 in in IN cord-005646-xhx9pzhj 1948 8 knowledge knowledge NN cord-005646-xhx9pzhj 1948 9 and and CC cord-005646-xhx9pzhj 1948 10 practice practice NN cord-005646-xhx9pzhj 1948 11 in in IN cord-005646-xhx9pzhj 1948 12 the the DT cord-005646-xhx9pzhj 1948 13 trainee trainee NN cord-005646-xhx9pzhj 1948 14 . . . cord-005646-xhx9pzhj 1949 1 Being be VBG cord-005646-xhx9pzhj 1949 2 an an DT cord-005646-xhx9pzhj 1949 3 effective effective JJ cord-005646-xhx9pzhj 1949 4 teacher teacher NN cord-005646-xhx9pzhj 1949 5 should should MD cord-005646-xhx9pzhj 1949 6 not not RB cord-005646-xhx9pzhj 1949 7 be be VB cord-005646-xhx9pzhj 1949 8 a a DT cord-005646-xhx9pzhj 1949 9 " " `` cord-005646-xhx9pzhj 1949 10 gift gift NN cord-005646-xhx9pzhj 1949 11 " " '' cord-005646-xhx9pzhj 1949 12 of of IN cord-005646-xhx9pzhj 1949 13 a a DT cord-005646-xhx9pzhj 1949 14 privileged privileged JJ cord-005646-xhx9pzhj 1949 15 few few JJ cord-005646-xhx9pzhj 1949 16 . . . cord-005646-xhx9pzhj 1950 1 The the DT cord-005646-xhx9pzhj 1950 2 ICU ICU NNP cord-005646-xhx9pzhj 1950 3 provides provide VBZ cord-005646-xhx9pzhj 1950 4 a a DT cord-005646-xhx9pzhj 1950 5 fertile fertile JJ cord-005646-xhx9pzhj 1950 6 ground ground NN cord-005646-xhx9pzhj 1950 7 for for IN cord-005646-xhx9pzhj 1950 8 using use VBG cord-005646-xhx9pzhj 1950 9 a a DT cord-005646-xhx9pzhj 1950 10 variety variety NN cord-005646-xhx9pzhj 1950 11 of of IN cord-005646-xhx9pzhj 1950 12 methods method NNS cord-005646-xhx9pzhj 1950 13 for for IN cord-005646-xhx9pzhj 1950 14 teaching teaching NN cord-005646-xhx9pzhj 1950 15 , , , cord-005646-xhx9pzhj 1950 16 e.g. e.g. RB cord-005646-xhx9pzhj 1950 17 didactic didactic JJ cord-005646-xhx9pzhj 1950 18 , , , cord-005646-xhx9pzhj 1950 19 at at IN cord-005646-xhx9pzhj 1950 20 the the DT cord-005646-xhx9pzhj 1950 21 bedside bedside NN cord-005646-xhx9pzhj 1950 22 , , , cord-005646-xhx9pzhj 1950 23 emergencies emergency NNS cord-005646-xhx9pzhj 1950 24 , , , cord-005646-xhx9pzhj 1950 25 and and CC cord-005646-xhx9pzhj 1950 26 in in IN cord-005646-xhx9pzhj 1950 27 the the DT cord-005646-xhx9pzhj 1950 28 performance performance NN cord-005646-xhx9pzhj 1950 29 ofproeeAures ofproeeaure NNS cord-005646-xhx9pzhj 1950 30 . . . cord-005646-xhx9pzhj 1951 1 In in IN cord-005646-xhx9pzhj 1951 2 this this DT cord-005646-xhx9pzhj 1951 3 environment environment NN cord-005646-xhx9pzhj 1951 4 , , , cord-005646-xhx9pzhj 1951 5 much much JJ cord-005646-xhx9pzhj 1951 6 can can MD cord-005646-xhx9pzhj 1951 7 be be VB cord-005646-xhx9pzhj 1951 8 learned learn VBN cord-005646-xhx9pzhj 1951 9 . . . cord-005646-xhx9pzhj 1952 1 We -PRON- PRP cord-005646-xhx9pzhj 1952 2 have have VBP cord-005646-xhx9pzhj 1952 3 embarked embark VBN cord-005646-xhx9pzhj 1952 4 upon upon IN cord-005646-xhx9pzhj 1952 5 a a DT cord-005646-xhx9pzhj 1952 6 program program NN cord-005646-xhx9pzhj 1952 7 to to TO cord-005646-xhx9pzhj 1952 8 facilitate facilitate VB cord-005646-xhx9pzhj 1952 9 this this DT cord-005646-xhx9pzhj 1952 10 learning learning NN cord-005646-xhx9pzhj 1952 11 process process NN cord-005646-xhx9pzhj 1952 12 . . . cord-005646-xhx9pzhj 1953 1 I -PRON- PRP cord-005646-xhx9pzhj 1953 2 ) ) -RRB- cord-005646-xhx9pzhj 1954 1 Teaching teaching NN cord-005646-xhx9pzhj 1954 2 needs need VBZ cord-005646-xhx9pzhj 1954 3 to to TO cord-005646-xhx9pzhj 1954 4 be be VB cord-005646-xhx9pzhj 1954 5 recognized recognize VBN cord-005646-xhx9pzhj 1954 6 as as IN cord-005646-xhx9pzhj 1954 7 the the DT cord-005646-xhx9pzhj 1954 8 foundation foundation NN cord-005646-xhx9pzhj 1954 9 of of IN cord-005646-xhx9pzhj 1954 10 good good JJ cord-005646-xhx9pzhj 1954 11 clinical clinical JJ cord-005646-xhx9pzhj 1954 12 care care NN cord-005646-xhx9pzhj 1954 13 , , , cord-005646-xhx9pzhj 1954 14 i.e. i.e. FW cord-005646-xhx9pzhj 1954 15 , , , cord-005646-xhx9pzhj 1954 16 patient patient JJ cord-005646-xhx9pzhj 1954 17 related relate VBN cord-005646-xhx9pzhj 1954 18 , , , cord-005646-xhx9pzhj 1954 19 and and CC cord-005646-xhx9pzhj 1954 20 in in IN cord-005646-xhx9pzhj 1954 21 its -PRON- PRP$ cord-005646-xhx9pzhj 1954 22 ability ability NN cord-005646-xhx9pzhj 1954 23 to to TO cord-005646-xhx9pzhj 1954 24 generate generate VB cord-005646-xhx9pzhj 1954 25 discussion discussion NN cord-005646-xhx9pzhj 1954 26 and and CC cord-005646-xhx9pzhj 1954 27 research research NN cord-005646-xhx9pzhj 1954 28 investigation investigation NN cord-005646-xhx9pzhj 1954 29 . . . cord-005646-xhx9pzhj 1955 1 2 2 LS cord-005646-xhx9pzhj 1955 2 ) ) -RRB- cord-005646-xhx9pzhj 1956 1 Teaching teaching NN cord-005646-xhx9pzhj 1956 2 structurally structurally RB cord-005646-xhx9pzhj 1956 3 has have VBZ cord-005646-xhx9pzhj 1956 4 many many JJ cord-005646-xhx9pzhj 1956 5 components component NNS cord-005646-xhx9pzhj 1956 6 including include VBG cord-005646-xhx9pzhj 1956 7 the the DT cord-005646-xhx9pzhj 1956 8 speaker speaker NN cord-005646-xhx9pzhj 1956 9 , , , cord-005646-xhx9pzhj 1956 10 audience audience NN cord-005646-xhx9pzhj 1956 11 , , , cord-005646-xhx9pzhj 1956 12 varying vary VBG cord-005646-xhx9pzhj 1956 13 situations situation NNS cord-005646-xhx9pzhj 1956 14 , , , cord-005646-xhx9pzhj 1956 15 and and CC cord-005646-xhx9pzhj 1956 16 the the DT cord-005646-xhx9pzhj 1956 17 message message NN cord-005646-xhx9pzhj 1956 18 delivered deliver VBN cord-005646-xhx9pzhj 1956 19 . . . cord-005646-xhx9pzhj 1957 1 3 3 LS cord-005646-xhx9pzhj 1957 2 ) ) -RRB- cord-005646-xhx9pzhj 1957 3 Establishment Establishment NNP cord-005646-xhx9pzhj 1957 4 of of IN cord-005646-xhx9pzhj 1957 5 a a DT cord-005646-xhx9pzhj 1957 6 program program NN cord-005646-xhx9pzhj 1957 7 using use VBG cord-005646-xhx9pzhj 1957 8 these these DT cord-005646-xhx9pzhj 1957 9 components component NNS cord-005646-xhx9pzhj 1957 10 to to TO cord-005646-xhx9pzhj 1957 11 enhance enhance VB cord-005646-xhx9pzhj 1957 12 teaching teaching NN cord-005646-xhx9pzhj 1957 13 abilities ability NNS cord-005646-xhx9pzhj 1957 14 at at IN cord-005646-xhx9pzhj 1957 15 all all DT cord-005646-xhx9pzhj 1957 16 levels level NNS cord-005646-xhx9pzhj 1957 17 , , , cord-005646-xhx9pzhj 1957 18 a a LS cord-005646-xhx9pzhj 1957 19 ) ) -RRB- cord-005646-xhx9pzhj 1957 20 Evaluate evaluate VB cord-005646-xhx9pzhj 1957 21 base base NN cord-005646-xhx9pzhj 1957 22 - - HYPH cord-005646-xhx9pzhj 1957 23 line line NN cord-005646-xhx9pzhj 1957 24 teaching teaching NN cord-005646-xhx9pzhj 1957 25 skills skill NNS cord-005646-xhx9pzhj 1957 26 initially initially RB cord-005646-xhx9pzhj 1957 27 , , , cord-005646-xhx9pzhj 1957 28 b b LS cord-005646-xhx9pzhj 1957 29 ) ) -RRB- cord-005646-xhx9pzhj 1957 30 Individualize individualize VB cord-005646-xhx9pzhj 1957 31 interventions intervention NNS cord-005646-xhx9pzhj 1957 32 to to TO cord-005646-xhx9pzhj 1957 33 improve improve VB cord-005646-xhx9pzhj 1957 34 teaching teaching NN cord-005646-xhx9pzhj 1957 35 skills skill NNS cord-005646-xhx9pzhj 1957 36 , , , cord-005646-xhx9pzhj 1957 37 e e LS cord-005646-xhx9pzhj 1957 38 ) ) -RRB- cord-005646-xhx9pzhj 1957 39 Demonstration demonstration NN cord-005646-xhx9pzhj 1957 40 of of IN cord-005646-xhx9pzhj 1957 41 learned learn VBN cord-005646-xhx9pzhj 1957 42 skills skill NNS cord-005646-xhx9pzhj 1957 43 with with IN cord-005646-xhx9pzhj 1957 44 re re NN cord-005646-xhx9pzhj 1957 45 - - NN cord-005646-xhx9pzhj 1957 46 evaluation evaluation NN cord-005646-xhx9pzhj 1957 47 . . . cord-005646-xhx9pzhj 1958 1 This this DT cord-005646-xhx9pzhj 1958 2 process process NN cord-005646-xhx9pzhj 1958 3 is be VBZ cord-005646-xhx9pzhj 1958 4 analogous analogous JJ cord-005646-xhx9pzhj 1958 5 to to IN cord-005646-xhx9pzhj 1958 6 the the DT cord-005646-xhx9pzhj 1958 7 analysis analysis NN cord-005646-xhx9pzhj 1958 8 of of IN cord-005646-xhx9pzhj 1958 9 a a DT cord-005646-xhx9pzhj 1958 10 clinical clinical JJ cord-005646-xhx9pzhj 1958 11 disorder disorder NN cord-005646-xhx9pzhj 1958 12 in in IN cord-005646-xhx9pzhj 1958 13 a a DT cord-005646-xhx9pzhj 1958 14 patient patient NN cord-005646-xhx9pzhj 1958 15 which which WDT cord-005646-xhx9pzhj 1958 16 , , , cord-005646-xhx9pzhj 1958 17 once once RB cord-005646-xhx9pzhj 1958 18 recognized recognize VBN cord-005646-xhx9pzhj 1958 19 , , , cord-005646-xhx9pzhj 1958 20 interventions intervention NNS cord-005646-xhx9pzhj 1958 21 are be VBP cord-005646-xhx9pzhj 1958 22 then then RB cord-005646-xhx9pzhj 1958 23 instituted institute VBN cord-005646-xhx9pzhj 1958 24 and and CC cord-005646-xhx9pzhj 1958 25 then then RB cord-005646-xhx9pzhj 1958 26 re re VB cord-005646-xhx9pzhj 1958 27 - - VBN cord-005646-xhx9pzhj 1958 28 evaluated evaluate VBN cord-005646-xhx9pzhj 1958 29 . . . cord-005646-xhx9pzhj 1959 1 4 4 LS cord-005646-xhx9pzhj 1959 2 ) ) -RRB- cord-005646-xhx9pzhj 1959 3 Instill instill VB cord-005646-xhx9pzhj 1959 4 the the DT cord-005646-xhx9pzhj 1959 5 desire desire NN cord-005646-xhx9pzhj 1959 6 to to TO cord-005646-xhx9pzhj 1959 7 use use VB cord-005646-xhx9pzhj 1959 8 these these DT cord-005646-xhx9pzhj 1959 9 attained attain VBN cord-005646-xhx9pzhj 1959 10 skills skill NNS cord-005646-xhx9pzhj 1959 11 to to TO cord-005646-xhx9pzhj 1959 12 teach teach VB cord-005646-xhx9pzhj 1959 13 and and CC cord-005646-xhx9pzhj 1959 14 interest interest VB cord-005646-xhx9pzhj 1959 15 others other NNS cord-005646-xhx9pzhj 1959 16 to to TO cord-005646-xhx9pzhj 1959 17 teach teach VB cord-005646-xhx9pzhj 1959 18 . . . cord-005646-xhx9pzhj 1960 1 Teaching teach VBG cord-005646-xhx9pzhj 1960 2 excellence excellence NN cord-005646-xhx9pzhj 1960 3 should should MD cord-005646-xhx9pzhj 1960 4 be be VB cord-005646-xhx9pzhj 1960 5 recognized recognize VBN cord-005646-xhx9pzhj 1960 6 through through IN cord-005646-xhx9pzhj 1960 7 awards award NNS cord-005646-xhx9pzhj 1960 8 , , , cord-005646-xhx9pzhj 1960 9 honors honor NNS cord-005646-xhx9pzhj 1960 10 , , , cord-005646-xhx9pzhj 1960 11 and and CC cord-005646-xhx9pzhj 1960 12 academic academic JJ cord-005646-xhx9pzhj 1960 13 advancement advancement NN cord-005646-xhx9pzhj 1960 14 . . . cord-005646-xhx9pzhj 1961 1 A a DT cord-005646-xhx9pzhj 1961 2 major major JJ cord-005646-xhx9pzhj 1961 3 emphasis emphasis NN cord-005646-xhx9pzhj 1961 4 of of IN cord-005646-xhx9pzhj 1961 5 this this DT cord-005646-xhx9pzhj 1961 6 program program NN cord-005646-xhx9pzhj 1961 7 is be VBZ cord-005646-xhx9pzhj 1961 8 to to TO cord-005646-xhx9pzhj 1961 9 provide provide VB cord-005646-xhx9pzhj 1961 10 participants participant NNS cord-005646-xhx9pzhj 1961 11 with with IN cord-005646-xhx9pzhj 1961 12 skills skill NNS cord-005646-xhx9pzhj 1961 13 necessary necessary JJ cord-005646-xhx9pzhj 1961 14 to to TO cord-005646-xhx9pzhj 1961 15 teach teach VB cord-005646-xhx9pzhj 1961 16 thought thought NN cord-005646-xhx9pzhj 1961 17 processes process NNS cord-005646-xhx9pzhj 1961 18 , , , cord-005646-xhx9pzhj 1961 19 decision decision NN cord-005646-xhx9pzhj 1961 20 - - HYPH cord-005646-xhx9pzhj 1961 21 making make VBG cord-005646-xhx9pzhj 1961 22 skills skill NNS cord-005646-xhx9pzhj 1961 23 ( ( -LRB- cord-005646-xhx9pzhj 1961 24 what what WP cord-005646-xhx9pzhj 1961 25 to to TO cord-005646-xhx9pzhj 1961 26 do do VB cord-005646-xhx9pzhj 1961 27 , , , cord-005646-xhx9pzhj 1961 28 what what WP cord-005646-xhx9pzhj 1961 29 to to TO cord-005646-xhx9pzhj 1961 30 avoid avoid VB cord-005646-xhx9pzhj 1961 31 ) ) -RRB- cord-005646-xhx9pzhj 1961 32 and and CC cord-005646-xhx9pzhj 1961 33 implementing implement VBG cord-005646-xhx9pzhj 1961 34 appropriate appropriate JJ cord-005646-xhx9pzhj 1961 35 management management NN cord-005646-xhx9pzhj 1961 36 during during IN cord-005646-xhx9pzhj 1961 37 stressful stressful JJ cord-005646-xhx9pzhj 1961 38 emergency emergency NN cord-005646-xhx9pzhj 1961 39 situations situation NNS cord-005646-xhx9pzhj 1961 40 common common JJ cord-005646-xhx9pzhj 1961 41 to to IN cord-005646-xhx9pzhj 1961 42 the the DT cord-005646-xhx9pzhj 1961 43 PICU PICU NNP cord-005646-xhx9pzhj 1961 44 . . . cord-005646-xhx9pzhj 1962 1 Introduction introduction NN cord-005646-xhx9pzhj 1962 2 : : : cord-005646-xhx9pzhj 1963 1 Many many JJ cord-005646-xhx9pzhj 1963 2 " " `` cord-005646-xhx9pzhj 1963 3 e e NN cord-005646-xhx9pzhj 1963 4 - - NN cord-005646-xhx9pzhj 1963 5 mail mail NN cord-005646-xhx9pzhj 1963 6 based base VBN cord-005646-xhx9pzhj 1963 7 discussion discussion NN cord-005646-xhx9pzhj 1963 8 groups group NNS cord-005646-xhx9pzhj 1963 9 exist exist VBP cord-005646-xhx9pzhj 1963 10 on on IN cord-005646-xhx9pzhj 1963 11 the the DT cord-005646-xhx9pzhj 1963 12 Internet internet NN cord-005646-xhx9pzhj 1963 13 to to TO cord-005646-xhx9pzhj 1963 14 provide provide VB cord-005646-xhx9pzhj 1963 15 medical medical JJ cord-005646-xhx9pzhj 1963 16 professionals professional NNS cord-005646-xhx9pzhj 1963 17 with with IN cord-005646-xhx9pzhj 1963 18 a a DT cord-005646-xhx9pzhj 1963 19 rapidly rapidly RB cord-005646-xhx9pzhj 1963 20 responsive responsive JJ cord-005646-xhx9pzhj 1963 21 medium medium NN cord-005646-xhx9pzhj 1963 22 for for IN cord-005646-xhx9pzhj 1963 23 the the DT cord-005646-xhx9pzhj 1963 24 international international JJ cord-005646-xhx9pzhj 1963 25 exchange exchange NN cord-005646-xhx9pzhj 1963 26 of of IN cord-005646-xhx9pzhj 1963 27 ideas idea NNS cord-005646-xhx9pzhj 1963 28 relating relate VBG cord-005646-xhx9pzhj 1963 29 to to IN cord-005646-xhx9pzhj 1963 30 patient patient JJ cord-005646-xhx9pzhj 1963 31 care care NN cord-005646-xhx9pzhj 1963 32 . . . cord-005646-xhx9pzhj 1964 1 Several several JJ cord-005646-xhx9pzhj 1964 2 such such JJ cord-005646-xhx9pzhj 1964 3 lists list NNS cord-005646-xhx9pzhj 1964 4 each each DT cord-005646-xhx9pzhj 1964 5 serve serve VBP cord-005646-xhx9pzhj 1964 6 more more JJR cord-005646-xhx9pzhj 1964 7 than than IN cord-005646-xhx9pzhj 1964 8 a a DT cord-005646-xhx9pzhj 1964 9 thousand thousand CD cord-005646-xhx9pzhj 1964 10 professionals professional NNS cord-005646-xhx9pzhj 1964 11 in in IN cord-005646-xhx9pzhj 1964 12 more more JJR cord-005646-xhx9pzhj 1964 13 than than IN cord-005646-xhx9pzhj 1964 14 30 30 CD cord-005646-xhx9pzhj 1964 15 countries country NNS cord-005646-xhx9pzhj 1964 16 , , , cord-005646-xhx9pzhj 1964 17 each each DT cord-005646-xhx9pzhj 1964 18 distributing distribute VBG cord-005646-xhx9pzhj 1964 19 a a DT cord-005646-xhx9pzhj 1964 20 dozen dozen NN cord-005646-xhx9pzhj 1964 21 or or CC cord-005646-xhx9pzhj 1964 22 more more JJR cord-005646-xhx9pzhj 1964 23 messages message NNS cord-005646-xhx9pzhj 1964 24 each each DT cord-005646-xhx9pzhj 1964 25 day day NN cord-005646-xhx9pzhj 1964 26 to to IN cord-005646-xhx9pzhj 1964 27 every every DT cord-005646-xhx9pzhj 1964 28 subscriber subscriber NN cord-005646-xhx9pzhj 1964 29 . . . cord-005646-xhx9pzhj 1965 1 There there EX cord-005646-xhx9pzhj 1965 2 is be VBZ cord-005646-xhx9pzhj 1965 3 very very RB cord-005646-xhx9pzhj 1965 4 little little RB cord-005646-xhx9pzhj 1965 5 known known JJ cord-005646-xhx9pzhj 1965 6 about about IN cord-005646-xhx9pzhj 1965 7 the the DT cord-005646-xhx9pzhj 1965 8 time time NN cord-005646-xhx9pzhj 1965 9 being be VBG cord-005646-xhx9pzhj 1965 10 spent spend VBN cord-005646-xhx9pzhj 1965 11 by by IN cord-005646-xhx9pzhj 1965 12 professionals professional NNS cord-005646-xhx9pzhj 1965 13 interacting interact VBG cord-005646-xhx9pzhj 1965 14 with with IN cord-005646-xhx9pzhj 1965 15 these these DT cord-005646-xhx9pzhj 1965 16 lists list NNS cord-005646-xhx9pzhj 1965 17 , , , cord-005646-xhx9pzhj 1965 18 and and CC cord-005646-xhx9pzhj 1965 19 very very RB cord-005646-xhx9pzhj 1965 20 little little RB cord-005646-xhx9pzhj 1965 21 known known JJ cord-005646-xhx9pzhj 1965 22 about about IN cord-005646-xhx9pzhj 1965 23 the the DT cord-005646-xhx9pzhj 1965 24 impact impact NN cord-005646-xhx9pzhj 1965 25 of of IN cord-005646-xhx9pzhj 1965 26 the the DT cord-005646-xhx9pzhj 1965 27 discussions discussion NNS cord-005646-xhx9pzhj 1965 28 on on IN cord-005646-xhx9pzhj 1965 29 patient patient JJ cord-005646-xhx9pzhj 1965 30 care care NN cord-005646-xhx9pzhj 1965 31 . . . cord-005646-xhx9pzhj 1966 1 We -PRON- PRP cord-005646-xhx9pzhj 1966 2 wished wish VBD cord-005646-xhx9pzhj 1966 3 to to TO cord-005646-xhx9pzhj 1966 4 test test VB cord-005646-xhx9pzhj 1966 5 the the DT cord-005646-xhx9pzhj 1966 6 hypothesis hypothesis NN cord-005646-xhx9pzhj 1966 7 that that IN cord-005646-xhx9pzhj 1966 8 these these DT cord-005646-xhx9pzhj 1966 9 discussion discussion NN cord-005646-xhx9pzhj 1966 10 groups group NNS cord-005646-xhx9pzhj 1966 11 provide provide VBP cord-005646-xhx9pzhj 1966 12 infortuation infortuation NN cord-005646-xhx9pzhj 1966 13 which which WDT cord-005646-xhx9pzhj 1966 14 is be VBZ cord-005646-xhx9pzhj 1966 15 being be VBG cord-005646-xhx9pzhj 1966 16 used use VBN cord-005646-xhx9pzhj 1966 17 to to TO cord-005646-xhx9pzhj 1966 18 change change VB cord-005646-xhx9pzhj 1966 19 the the DT cord-005646-xhx9pzhj 1966 20 care care NN cord-005646-xhx9pzhj 1966 21 of of IN cord-005646-xhx9pzhj 1966 22 individual individual JJ cord-005646-xhx9pzhj 1966 23 patients patient NNS cord-005646-xhx9pzhj 1966 24 and and CC cord-005646-xhx9pzhj 1966 25 the the DT cord-005646-xhx9pzhj 1966 26 general general JJ cord-005646-xhx9pzhj 1966 27 approach approach NN cord-005646-xhx9pzhj 1966 28 to to IN cord-005646-xhx9pzhj 1966 29 patient patient JJ cord-005646-xhx9pzhj 1966 30 problems problem NNS cord-005646-xhx9pzhj 1966 31 . . . cord-005646-xhx9pzhj 1967 1 Methods method NNS cord-005646-xhx9pzhj 1967 2 : : : cord-005646-xhx9pzhj 1967 3 In in IN cord-005646-xhx9pzhj 1967 4 early early JJ cord-005646-xhx9pzhj 1967 5 January January NNP cord-005646-xhx9pzhj 1967 6 1996 1996 CD cord-005646-xhx9pzhj 1967 7 a a DT cord-005646-xhx9pzhj 1967 8 pilot pilot NN cord-005646-xhx9pzhj 1967 9 electronic electronic JJ cord-005646-xhx9pzhj 1967 10 survey survey NN cord-005646-xhx9pzhj 1967 11 was be VBD cord-005646-xhx9pzhj 1967 12 sent send VBN cord-005646-xhx9pzhj 1967 13 to to IN cord-005646-xhx9pzhj 1967 14 a a DT cord-005646-xhx9pzhj 1967 15 small small JJ cord-005646-xhx9pzhj 1967 16 fraction fraction NN cord-005646-xhx9pzhj 1967 17 ( ( -LRB- cord-005646-xhx9pzhj 1967 18 N=63 N=63 NNP cord-005646-xhx9pzhj 1967 19 ) ) -RRB- cord-005646-xhx9pzhj 1967 20 of of IN cord-005646-xhx9pzhj 1967 21 the the DT cord-005646-xhx9pzhj 1967 22 memberships membership NNS cord-005646-xhx9pzhj 1967 23 of of IN cord-005646-xhx9pzhj 1967 24 2 2 CD cord-005646-xhx9pzhj 1967 25 e e NN cord-005646-xhx9pzhj 1967 26 - - NN cord-005646-xhx9pzhj 1967 27 mail mail NN cord-005646-xhx9pzhj 1967 28 discussion discussion NN cord-005646-xhx9pzhj 1967 29 groups group NNS cord-005646-xhx9pzhj 1967 30 , , , cord-005646-xhx9pzhj 1967 31 PICU@its.mew.edu PICU@its.mew.edu NNPS cord-005646-xhx9pzhj 1967 32 , , , cord-005646-xhx9pzhj 1967 33 and and CC cord-005646-xhx9pzhj 1967 34 NICU-NET@u.washington.edu NICU-NET@u.washington.edu NNP cord-005646-xhx9pzhj 1968 1 ( ( -LRB- cord-005646-xhx9pzhj 1968 2 the the DT cord-005646-xhx9pzhj 1968 3 full full JJ cord-005646-xhx9pzhj 1968 4 memberships membership NNS cord-005646-xhx9pzhj 1968 5 of of IN cord-005646-xhx9pzhj 1968 6 both both DT cord-005646-xhx9pzhj 1968 7 . . . cord-005646-xhx9pzhj 1969 1 groups group NNS cord-005646-xhx9pzhj 1970 1 ( ( -LRB- cord-005646-xhx9pzhj 1970 2 N n NN cord-005646-xhx9pzhj 1970 3 = = SYM cord-005646-xhx9pzhj 1970 4 t439 t439 NNS cord-005646-xhx9pzhj 1970 5 for for IN cord-005646-xhx9pzhj 1970 6 NICU NICU NNP cord-005646-xhx9pzhj 1970 7 - - HYPH cord-005646-xhx9pzhj 1970 8 NET NET NNP cord-005646-xhx9pzhj 1970 9 , , , cord-005646-xhx9pzhj 1970 10 N=1045 N=1045 NNP cord-005646-xhx9pzhj 1970 11 for for IN cord-005646-xhx9pzhj 1970 12 PICU PICU NNP cord-005646-xhx9pzhj 1970 13 ) ) -RRB- cord-005646-xhx9pzhj 1970 14 will will MD cord-005646-xhx9pzhj 1970 15 be be VB cord-005646-xhx9pzhj 1970 16 surveyed survey VBN cord-005646-xhx9pzhj 1970 17 in in IN cord-005646-xhx9pzhj 1970 18 early early JJ cord-005646-xhx9pzhj 1970 19 February February NNP cord-005646-xhx9pzhj 1970 20 of of IN cord-005646-xhx9pzhj 1970 21 1996 1996 CD cord-005646-xhx9pzhj 1970 22 ) ) -RRB- cord-005646-xhx9pzhj 1970 23 . . . cord-005646-xhx9pzhj 1971 1 Participants participant NNS cord-005646-xhx9pzhj 1971 2 were be VBD cord-005646-xhx9pzhj 1971 3 asked ask VBN cord-005646-xhx9pzhj 1971 4 for for IN cord-005646-xhx9pzhj 1971 5 demographic demographic JJ cord-005646-xhx9pzhj 1971 6 information information NN cord-005646-xhx9pzhj 1971 7 , , , cord-005646-xhx9pzhj 1971 8 experience experience NN cord-005646-xhx9pzhj 1971 9 and and CC cord-005646-xhx9pzhj 1971 10 skill skill NN cord-005646-xhx9pzhj 1971 11 level level NN cord-005646-xhx9pzhj 1971 12 relating relate VBG cord-005646-xhx9pzhj 1971 13 to to IN cord-005646-xhx9pzhj 1971 14 e e NN cord-005646-xhx9pzhj 1971 15 - - NN cord-005646-xhx9pzhj 1971 16 mail mail NN cord-005646-xhx9pzhj 1971 17 , , , cord-005646-xhx9pzhj 1971 18 time time NN cord-005646-xhx9pzhj 1971 19 spent spend VBN cord-005646-xhx9pzhj 1971 20 with with IN cord-005646-xhx9pzhj 1971 21 the the DT cord-005646-xhx9pzhj 1971 22 discussion discussion NN cord-005646-xhx9pzhj 1971 23 groups group NNS cord-005646-xhx9pzhj 1971 24 , , , cord-005646-xhx9pzhj 1971 25 perceived perceive VBN cord-005646-xhx9pzhj 1971 26 usefulness usefulness NN cord-005646-xhx9pzhj 1971 27 of of IN cord-005646-xhx9pzhj 1971 28 different different JJ cord-005646-xhx9pzhj 1971 29 types type NNS cord-005646-xhx9pzhj 1971 30 of of IN cord-005646-xhx9pzhj 1971 31 discussions discussion NNS cord-005646-xhx9pzhj 1971 32 , , , cord-005646-xhx9pzhj 1971 33 and and CC cord-005646-xhx9pzhj 1971 34 the the DT cord-005646-xhx9pzhj 1971 35 ways way NNS cord-005646-xhx9pzhj 1971 36 in in IN cord-005646-xhx9pzhj 1971 37 which which WDT cord-005646-xhx9pzhj 1971 38 the the DT cord-005646-xhx9pzhj 1971 39 discussions discussion NNS cord-005646-xhx9pzhj 1971 40 were be VBD cord-005646-xhx9pzhj 1971 41 used use VBN cord-005646-xhx9pzhj 1971 42 clinically clinically RB cord-005646-xhx9pzhj 1971 43 . . . cord-005646-xhx9pzhj 1972 1 The the DT cord-005646-xhx9pzhj 1972 2 pilot pilot NN cord-005646-xhx9pzhj 1972 3 study study NN cord-005646-xhx9pzhj 1972 4 was be VBD cord-005646-xhx9pzhj 1972 5 analyzed analyze VBN cord-005646-xhx9pzhj 1972 6 for for IN cord-005646-xhx9pzhj 1972 7 construct construct VB cord-005646-xhx9pzhj 1972 8 validity validity NN cord-005646-xhx9pzhj 1972 9 by by IN cord-005646-xhx9pzhj 1972 10 correlating correlate VBG cord-005646-xhx9pzhj 1972 11 an an DT cord-005646-xhx9pzhj 1972 12 overall overall JJ cord-005646-xhx9pzhj 1972 13 assessment assessment NN cord-005646-xhx9pzhj 1972 14 question question NN cord-005646-xhx9pzhj 1972 15 with with IN cord-005646-xhx9pzhj 1972 16 a a DT cord-005646-xhx9pzhj 1972 17 summary summary NN cord-005646-xhx9pzhj 1972 18 of of IN cord-005646-xhx9pzhj 1972 19 the the DT cord-005646-xhx9pzhj 1972 20 specific specific JJ cord-005646-xhx9pzhj 1972 21 questions question NNS cord-005646-xhx9pzhj 1972 22 . . . cord-005646-xhx9pzhj 1973 1 Scale scale NN cord-005646-xhx9pzhj 1973 2 reliability reliability NN cord-005646-xhx9pzhj 1973 3 was be VBD cord-005646-xhx9pzhj 1973 4 measured measure VBN cord-005646-xhx9pzhj 1973 5 by by IN cord-005646-xhx9pzhj 1973 6 Cronbach Cronbach NNP cord-005646-xhx9pzhj 1973 7 's 's POS cord-005646-xhx9pzhj 1973 8 alpha alpha NN cord-005646-xhx9pzhj 1973 9 statistic statistic NN cord-005646-xhx9pzhj 1973 10 . . . cord-005646-xhx9pzhj 1974 1 Results result NNS cord-005646-xhx9pzhj 1974 2 : : : cord-005646-xhx9pzhj 1975 1 The the DT cord-005646-xhx9pzhj 1975 2 pilot pilot NN cord-005646-xhx9pzhj 1975 3 survey survey NN cord-005646-xhx9pzhj 1975 4 response response NN cord-005646-xhx9pzhj 1975 5 rate rate NN cord-005646-xhx9pzhj 1975 6 was be VBD cord-005646-xhx9pzhj 1975 7 30163 30163 CD cord-005646-xhx9pzhj 1975 8 ( ( -LRB- cord-005646-xhx9pzhj 1975 9 48 48 CD cord-005646-xhx9pzhj 1975 10 % % NN cord-005646-xhx9pzhj 1975 11 ) ) -RRB- cord-005646-xhx9pzhj 1975 12 . . . cord-005646-xhx9pzhj 1976 1 The the DT cord-005646-xhx9pzhj 1976 2 majority majority NN cord-005646-xhx9pzhj 1976 3 of of IN cord-005646-xhx9pzhj 1976 4 respondents respondent NNS cord-005646-xhx9pzhj 1976 5 were be VBD cord-005646-xhx9pzhj 1976 6 male male JJ cord-005646-xhx9pzhj 1976 7 physicians physician NNS cord-005646-xhx9pzhj 1976 8 , , , cord-005646-xhx9pzhj 1976 9 with with IN cord-005646-xhx9pzhj 1976 10 an an DT cord-005646-xhx9pzhj 1976 11 average average JJ cord-005646-xhx9pzhj 1976 12 age age NN cord-005646-xhx9pzhj 1976 13 of of IN cord-005646-xhx9pzhj 1976 14 39+_5 39+_5 CD cord-005646-xhx9pzhj 1976 15 years year NNS cord-005646-xhx9pzhj 1976 16 , , , cord-005646-xhx9pzhj 1976 17 who who WP cord-005646-xhx9pzhj 1976 18 had have VBD cord-005646-xhx9pzhj 1976 19 completed complete VBN cord-005646-xhx9pzhj 1976 20 subspecialty subspecialty JJ cord-005646-xhx9pzhj 1976 21 training training NN cord-005646-xhx9pzhj 1976 22 in in IN cord-005646-xhx9pzhj 1976 23 intensive intensive JJ cord-005646-xhx9pzhj 1976 24 care care NN cord-005646-xhx9pzhj 1976 25 , , , cord-005646-xhx9pzhj 1976 26 and and CC cord-005646-xhx9pzhj 1976 27 were be VBD cord-005646-xhx9pzhj 1976 28 working work VBG cord-005646-xhx9pzhj 1976 29 at at IN cord-005646-xhx9pzhj 1976 30 a a DT cord-005646-xhx9pzhj 1976 31 university university NN cord-005646-xhx9pzhj 1976 32 - - HYPH cord-005646-xhx9pzhj 1976 33 affiliated affiliate VBN cord-005646-xhx9pzhj 1976 34 hospital hospital NN cord-005646-xhx9pzhj 1976 35 . . . cord-005646-xhx9pzhj 1977 1 Most most RBS cord-005646-xhx9pzhj 1977 2 had have VBD cord-005646-xhx9pzhj 1977 3 been be VBN cord-005646-xhx9pzhj 1977 4 using use VBG cord-005646-xhx9pzhj 1977 5 e e NN cord-005646-xhx9pzhj 1977 6 - - NN cord-005646-xhx9pzhj 1977 7 malt malt NN cord-005646-xhx9pzhj 1977 8 for for IN cord-005646-xhx9pzhj 1977 9 more more JJR cord-005646-xhx9pzhj 1977 10 than than IN cord-005646-xhx9pzhj 1977 11 6 6 CD cord-005646-xhx9pzhj 1977 12 months month NNS cord-005646-xhx9pzhj 1977 13 , , , cord-005646-xhx9pzhj 1977 14 and and CC cord-005646-xhx9pzhj 1977 15 considered consider VBD cord-005646-xhx9pzhj 1977 16 themselves -PRON- PRP cord-005646-xhx9pzhj 1977 17 moderately moderately RB cord-005646-xhx9pzhj 1977 18 adept adept JJ cord-005646-xhx9pzhj 1977 19 in in IN cord-005646-xhx9pzhj 1977 20 that that DT cord-005646-xhx9pzhj 1977 21 use use NN cord-005646-xhx9pzhj 1977 22 . . . cord-005646-xhx9pzhj 1978 1 63 63 CD cord-005646-xhx9pzhj 1978 2 % % NN cord-005646-xhx9pzhj 1978 3 felt feel VBD cord-005646-xhx9pzhj 1978 4 that that IN cord-005646-xhx9pzhj 1978 5 the the DT cord-005646-xhx9pzhj 1978 6 list list NN cord-005646-xhx9pzhj 1978 7 helped help VBD cord-005646-xhx9pzhj 1978 8 weekly weekly RB cord-005646-xhx9pzhj 1978 9 to to TO cord-005646-xhx9pzhj 1978 10 keep keep VB cord-005646-xhx9pzhj 1978 11 them -PRON- PRP cord-005646-xhx9pzhj 1978 12 informed informed JJ cord-005646-xhx9pzhj 1978 13 about about IN cord-005646-xhx9pzhj 1978 14 current current JJ cord-005646-xhx9pzhj 1978 15 issues issue NNS cord-005646-xhx9pzhj 1978 16 and and CC cord-005646-xhx9pzhj 1978 17 practices practice NNS cord-005646-xhx9pzhj 1978 18 in in IN cord-005646-xhx9pzhj 1978 19 their -PRON- PRP$ cord-005646-xhx9pzhj 1978 20 field(s field(s NNP cord-005646-xhx9pzhj 1978 21 ) ) -RRB- cord-005646-xhx9pzhj 1978 22 , , , cord-005646-xhx9pzhj 1978 23 and and CC cord-005646-xhx9pzhj 1978 24 57 57 CD cord-005646-xhx9pzhj 1978 25 % % NN cord-005646-xhx9pzhj 1978 26 felt feel VBD cord-005646-xhx9pzhj 1978 27 that that IN cord-005646-xhx9pzhj 1978 28 , , , cord-005646-xhx9pzhj 1978 29 at at IN cord-005646-xhx9pzhj 1978 30 least least JJS cord-005646-xhx9pzhj 1978 31 monthly monthly RB cord-005646-xhx9pzhj 1978 32 , , , cord-005646-xhx9pzhj 1978 33 they -PRON- PRP cord-005646-xhx9pzhj 1978 34 used use VBD cord-005646-xhx9pzhj 1978 35 information information NN cord-005646-xhx9pzhj 1978 36 from from IN cord-005646-xhx9pzhj 1978 37 the the DT cord-005646-xhx9pzhj 1978 38 list(s list(s NNP cord-005646-xhx9pzhj 1978 39 ) ) -RRB- cord-005646-xhx9pzhj 1978 40 that that WDT cord-005646-xhx9pzhj 1978 41 was be VBD cord-005646-xhx9pzhj 1978 42 not not RB cord-005646-xhx9pzhj 1978 43 readily readily RB cord-005646-xhx9pzhj 1978 44 available available JJ cord-005646-xhx9pzhj 1978 45 in in IN cord-005646-xhx9pzhj 1978 46 medical medical JJ cord-005646-xhx9pzhj 1978 47 journals journal NNS cord-005646-xhx9pzhj 1978 48 . . . cord-005646-xhx9pzhj 1979 1 Overall overall RB cord-005646-xhx9pzhj 1979 2 , , , cord-005646-xhx9pzhj 1979 3 75 75 CD cord-005646-xhx9pzhj 1979 4 % % NN cord-005646-xhx9pzhj 1979 5 agreed agree VBD cord-005646-xhx9pzhj 1979 6 that that IN cord-005646-xhx9pzhj 1979 7 the the DT cord-005646-xhx9pzhj 1979 8 list list NN cord-005646-xhx9pzhj 1979 9 improved improve VBD cord-005646-xhx9pzhj 1979 10 their -PRON- PRP$ cord-005646-xhx9pzhj 1979 11 professional professional JJ cord-005646-xhx9pzhj 1979 12 competency competency NN cord-005646-xhx9pzhj 1979 13 . . . cord-005646-xhx9pzhj 1980 1 When when WRB cord-005646-xhx9pzhj 1980 2 asked ask VBN cord-005646-xhx9pzhj 1980 3 to to TO cord-005646-xhx9pzhj 1980 4 compare compare VB cord-005646-xhx9pzhj 1980 5 the the DT cord-005646-xhx9pzhj 1980 6 value value NN cord-005646-xhx9pzhj 1980 7 of of IN cord-005646-xhx9pzhj 1980 8 6 6 CD cord-005646-xhx9pzhj 1980 9 months month NNS cord-005646-xhx9pzhj 1980 10 of of IN cord-005646-xhx9pzhj 1980 11 membership membership NN cord-005646-xhx9pzhj 1980 12 on on IN cord-005646-xhx9pzhj 1980 13 an an DT cord-005646-xhx9pzhj 1980 14 e e NN cord-005646-xhx9pzhj 1980 15 - - NN cord-005646-xhx9pzhj 1980 16 mail mail NN cord-005646-xhx9pzhj 1980 17 discussion discussion NN cord-005646-xhx9pzhj 1980 18 group group NN cord-005646-xhx9pzhj 1980 19 with with IN cord-005646-xhx9pzhj 1980 20 more more JJR cord-005646-xhx9pzhj 1980 21 traditional traditional JJ cord-005646-xhx9pzhj 1980 22 educational educational JJ cord-005646-xhx9pzhj 1980 23 media medium NNS cord-005646-xhx9pzhj 1980 24 , , , cord-005646-xhx9pzhj 1980 25 34 34 CD cord-005646-xhx9pzhj 1980 26 % % NN cord-005646-xhx9pzhj 1980 27 compared compare VBD cord-005646-xhx9pzhj 1980 28 it -PRON- PRP cord-005646-xhx9pzhj 1980 29 with with IN cord-005646-xhx9pzhj 1980 30 attending attend VBG cord-005646-xhx9pzhj 1980 31 a a DT cord-005646-xhx9pzhj 1980 32 national national JJ cord-005646-xhx9pzhj 1980 33 conference conference NN cord-005646-xhx9pzhj 1980 34 , , , cord-005646-xhx9pzhj 1980 35 and and CC cord-005646-xhx9pzhj 1980 36 26 26 CD cord-005646-xhx9pzhj 1980 37 % % NN cord-005646-xhx9pzhj 1980 38 compared compare VBD cord-005646-xhx9pzhj 1980 39 it -PRON- PRP cord-005646-xhx9pzhj 1980 40 to to IN cord-005646-xhx9pzhj 1980 41 a a DT cord-005646-xhx9pzhj 1980 42 journal journal NN cord-005646-xhx9pzhj 1980 43 subscription subscription NN cord-005646-xhx9pzhj 1980 44 . . . cord-005646-xhx9pzhj 1981 1 Cronbach Cronbach NNP cord-005646-xhx9pzhj 1981 2 's 's POS cord-005646-xhx9pzhj 1981 3 alpha alpha NN cord-005646-xhx9pzhj 1981 4 was be VBD cord-005646-xhx9pzhj 1981 5 .76 .76 NFP cord-005646-xhx9pzhj 1981 6 , , , cord-005646-xhx9pzhj 1981 7 Construct construct VB cord-005646-xhx9pzhj 1981 8 validity validity NN cord-005646-xhx9pzhj 1981 9 testing test VBG cord-005646-xhx9pzhj 1982 1 yielded yield VBN cord-005646-xhx9pzhj 1982 2 coeff=.50 coeff=.50 NNP cord-005646-xhx9pzhj 1982 3 , , , cord-005646-xhx9pzhj 1983 1 p p LS cord-005646-xhx9pzhj 1983 2 < < XX cord-005646-xhx9pzhj 1983 3 .05 .05 NFP cord-005646-xhx9pzhj 1983 4 . . . cord-005646-xhx9pzhj 1984 1 Conclusior~ conclusior~ JJ cord-005646-xhx9pzhj 1984 2 : : : cord-005646-xhx9pzhj 1984 3 Internet internet NN cord-005646-xhx9pzhj 1984 4 - - HYPH cord-005646-xhx9pzhj 1984 5 based base VBN cord-005646-xhx9pzhj 1984 6 e e NN cord-005646-xhx9pzhj 1984 7 - - NN cord-005646-xhx9pzhj 1984 8 mail mail NN cord-005646-xhx9pzhj 1984 9 discussion discussion NN cord-005646-xhx9pzhj 1984 10 groups group NNS cord-005646-xhx9pzhj 1984 11 for for IN cord-005646-xhx9pzhj 1984 12 health health NN cord-005646-xhx9pzhj 1984 13 care care NN cord-005646-xhx9pzhj 1984 14 professionals professional NNS cord-005646-xhx9pzhj 1984 15 can can MD cord-005646-xhx9pzhj 1984 16 be be VB cord-005646-xhx9pzhj 1984 17 an an DT cord-005646-xhx9pzhj 1984 18 important important JJ cord-005646-xhx9pzhj 1984 19 part part NN cord-005646-xhx9pzhj 1984 20 of of IN cord-005646-xhx9pzhj 1984 21 a a DT cord-005646-xhx9pzhj 1984 22 strategy strategy NN cord-005646-xhx9pzhj 1984 23 for for IN cord-005646-xhx9pzhj 1984 24 maintaining maintain VBG cord-005646-xhx9pzhj 1984 25 professional professional JJ cord-005646-xhx9pzhj 1984 26 competency competency NN cord-005646-xhx9pzhj 1984 27 . . . cord-005646-xhx9pzhj 1985 1 Despite despite IN cord-005646-xhx9pzhj 1985 2 the the DT cord-005646-xhx9pzhj 1985 3 very very RB cord-005646-xhx9pzhj 1985 4 low low JJ cord-005646-xhx9pzhj 1985 5 cost cost NN cord-005646-xhx9pzhj 1985 6 of of IN cord-005646-xhx9pzhj 1985 7 this this DT cord-005646-xhx9pzhj 1985 8 medium medium NN cord-005646-xhx9pzhj 1985 9 for for IN cord-005646-xhx9pzhj 1985 10 most most JJS cord-005646-xhx9pzhj 1985 11 , , , cord-005646-xhx9pzhj 1985 12 the the DT cord-005646-xhx9pzhj 1985 13 value value NN cord-005646-xhx9pzhj 1985 14 is be VBZ cord-005646-xhx9pzhj 1985 15 felt feel VBN cord-005646-xhx9pzhj 1985 16 to to TO cord-005646-xhx9pzhj 1985 17 be be VB cord-005646-xhx9pzhj 1985 18 comparable comparable JJ cord-005646-xhx9pzhj 1985 19 to to IN cord-005646-xhx9pzhj 1985 20 that that DT cord-005646-xhx9pzhj 1985 21 of of IN cord-005646-xhx9pzhj 1985 22 t t NN cord-005646-xhx9pzhj 1986 1 ~r ~r XX cord-005646-xhx9pzhj 1986 2 more more RBR cord-005646-xhx9pzhj 1986 3 expensive expensive JJ cord-005646-xhx9pzhj 1986 4 forums forum NNS cord-005646-xhx9pzhj 1986 5 for for IN cord-005646-xhx9pzhj 1986 6 education education NN cord-005646-xhx9pzhj 1986 7 . . . cord-005646-xhx9pzhj 1987 1 Further further JJ cord-005646-xhx9pzhj 1987 2 study study NN cord-005646-xhx9pzhj 1987 3 will will MD cord-005646-xhx9pzhj 1987 4 include include VB cord-005646-xhx9pzhj 1987 5 distribution distribution NN cord-005646-xhx9pzhj 1987 6 of of IN cord-005646-xhx9pzhj 1987 7 the the DT cord-005646-xhx9pzhj 1987 8 full full JJ cord-005646-xhx9pzhj 1987 9 survey survey NN cord-005646-xhx9pzhj 1987 10 in in IN cord-005646-xhx9pzhj 1987 11 early early JJ cord-005646-xhx9pzhj 1987 12 February February NNP cord-005646-xhx9pzhj 1987 13 of of IN cord-005646-xhx9pzhj 1987 14 1996 1996 CD cord-005646-xhx9pzhj 1987 15 . . . cord-005646-xhx9pzhj 1988 1 Fronk Fronk NNP cord-005646-xhx9pzhj 1988 2 Shann Shann NNP cord-005646-xhx9pzhj 1988 3 , , , cord-005646-xhx9pzhj 1988 4 Tony Tony NNP cord-005646-xhx9pzhj 1988 5 Slater Slater NNP cord-005646-xhx9pzhj 1988 6 , , , cord-005646-xhx9pzhj 1988 7 Gale Gale NNP cord-005646-xhx9pzhj 1988 8 Pearson Pearson NNP cord-005646-xhx9pzhj 1988 9 and and CC cord-005646-xhx9pzhj 1988 10 the the DT cord-005646-xhx9pzhj 1988 11 PIM PIM NNP cord-005646-xhx9pzhj 1988 12 Study Study NNP cord-005646-xhx9pzhj 1988 13 Group Group NNP cord-005646-xhx9pzhj 1989 1 We -PRON- PRP cord-005646-xhx9pzhj 1989 2 have have VBP cord-005646-xhx9pzhj 1989 3 developed develop VBN cord-005646-xhx9pzhj 1989 4 a a DT cord-005646-xhx9pzhj 1989 5 new new JJ cord-005646-xhx9pzhj 1989 6 score score NN cord-005646-xhx9pzhj 1989 7 for for IN cord-005646-xhx9pzhj 1989 8 predicting predict VBG cord-005646-xhx9pzhj 1989 9 the the DT cord-005646-xhx9pzhj 1989 10 risk risk NN cord-005646-xhx9pzhj 1989 11 of of IN cord-005646-xhx9pzhj 1989 12 mortality mortality NN cord-005646-xhx9pzhj 1989 13 in in IN cord-005646-xhx9pzhj 1989 14 children child NNS cord-005646-xhx9pzhj 1989 15 admitted admit VBN cord-005646-xhx9pzhj 1989 16 to to IN cord-005646-xhx9pzhj 1989 17 intensive intensive JJ cord-005646-xhx9pzhj 1989 18 care care NN cord-005646-xhx9pzhj 1989 19 . . . cord-005646-xhx9pzhj 1990 1 The the DT cord-005646-xhx9pzhj 1990 2 score score NN cord-005646-xhx9pzhj 1990 3 is be VBZ cord-005646-xhx9pzhj 1990 4 calculated calculate VBN cord-005646-xhx9pzhj 1990 5 from from IN cord-005646-xhx9pzhj 1990 6 only only RB cord-005646-xhx9pzhj 1990 7 seven seven CD cord-005646-xhx9pzhj 1990 8 variables variable NNS cord-005646-xhx9pzhj 1990 9 collected collect VBN cord-005646-xhx9pzhj 1990 10 at at IN cord-005646-xhx9pzhj 1990 11 the the DT cord-005646-xhx9pzhj 1990 12 time time NN cord-005646-xhx9pzhj 1990 13 of of IN cord-005646-xhx9pzhj 1990 14 admission admission NN cord-005646-xhx9pzhj 1990 15 to to IN cord-005646-xhx9pzhj 1990 16 ICU ICU NNP cord-005646-xhx9pzhj 1990 17 : : : cord-005646-xhx9pzhj 1990 18 mechanical mechanical JJ cord-005646-xhx9pzhj 1990 19 ventilation ventilation NN cord-005646-xhx9pzhj 1990 20 ( ( -LRB- cord-005646-xhx9pzhj 1990 21 yes yes UH cord-005646-xhx9pzhj 1990 22 / / SYM cord-005646-xhx9pzhj 1990 23 no no UH cord-005646-xhx9pzhj 1990 24 ) ) -RRB- cord-005646-xhx9pzhj 1990 25 , , , cord-005646-xhx9pzhj 1990 26 booked book VBD cord-005646-xhx9pzhj 1990 27 admission admission NN cord-005646-xhx9pzhj 1990 28 after after IN cord-005646-xhx9pzhj 1990 29 elective elective JJ cord-005646-xhx9pzhj 1990 30 surgery surgery NN cord-005646-xhx9pzhj 1991 1 ( ( -LRB- cord-005646-xhx9pzhj 1991 2 yes yes UH cord-005646-xhx9pzhj 1991 3 / / SYM cord-005646-xhx9pzhj 1991 4 no no UH cord-005646-xhx9pzhj 1991 5 ) ) -RRB- cord-005646-xhx9pzhj 1991 6 , , , cord-005646-xhx9pzhj 1991 7 the the DT cord-005646-xhx9pzhj 1991 8 presence presence NN cord-005646-xhx9pzhj 1991 9 of of IN cord-005646-xhx9pzhj 1991 10 any any DT cord-005646-xhx9pzhj 1991 11 one one CD cord-005646-xhx9pzhj 1991 12 of of IN cord-005646-xhx9pzhj 1991 13 14 14 CD cord-005646-xhx9pzhj 1991 14 specified specify VBN cord-005646-xhx9pzhj 1991 15 underlying underlying JJ cord-005646-xhx9pzhj 1991 16 conditions condition NNS cord-005646-xhx9pzhj 1991 17 , , , cord-005646-xhx9pzhj 1991 18 both both DT cord-005646-xhx9pzhj 1991 19 pupils pupil NNS cord-005646-xhx9pzhj 1991 20 fixed fix VBN cord-005646-xhx9pzhj 1991 21 to to IN cord-005646-xhx9pzhj 1991 22 light light NN cord-005646-xhx9pzhj 1991 23 ( ( -LRB- cord-005646-xhx9pzhj 1991 24 yes yes UH cord-005646-xhx9pzhj 1991 25 / / SYM cord-005646-xhx9pzhj 1991 26 no no UH cord-005646-xhx9pzhj 1991 27 ) ) -RRB- cord-005646-xhx9pzhj 1991 28 , , , cord-005646-xhx9pzhj 1991 29 the the DT cord-005646-xhx9pzhj 1991 30 base base NN cord-005646-xhx9pzhj 1991 31 excess excess NN cord-005646-xhx9pzhj 1991 32 , , , cord-005646-xhx9pzhj 1991 33 the the DT cord-005646-xhx9pzhj 1991 34 PaO pao JJ cord-005646-xhx9pzhj 1991 35 2 2 CD cord-005646-xhx9pzhj 1991 36 divided divide VBN cord-005646-xhx9pzhj 1991 37 by by IN cord-005646-xhx9pzhj 1991 38 the the DT cord-005646-xhx9pzhj 1991 39 FiO2 FiO2 NNS cord-005646-xhx9pzhj 1991 40 , , , cord-005646-xhx9pzhj 1991 41 and and CC cord-005646-xhx9pzhj 1991 42 the the DT cord-005646-xhx9pzhj 1991 43 systolic systolic JJ cord-005646-xhx9pzhj 1991 44 blood blood NN cord-005646-xhx9pzhj 1991 45 pressure pressure NN cord-005646-xhx9pzhj 1991 46 . . . cord-005646-xhx9pzhj 1992 1 Most Most JJS cord-005646-xhx9pzhj 1992 2 scores score NNS cord-005646-xhx9pzhj 1992 3 used use VBD cord-005646-xhx9pzhj 1992 4 to to TO cord-005646-xhx9pzhj 1992 5 predict predict VB cord-005646-xhx9pzhj 1992 6 outcome outcome NN cord-005646-xhx9pzhj 1992 7 in in IN cord-005646-xhx9pzhj 1992 8 intensive intensive JJ cord-005646-xhx9pzhj 1992 9 care care NN cord-005646-xhx9pzhj 1992 10 require require VBP cord-005646-xhx9pzhj 1992 11 the the DT cord-005646-xhx9pzhj 1992 12 collection collection NN cord-005646-xhx9pzhj 1992 13 of of IN cord-005646-xhx9pzhj 1992 14 a a DT cord-005646-xhx9pzhj 1992 15 large large JJ cord-005646-xhx9pzhj 1992 16 number number NN cord-005646-xhx9pzhj 1992 17 of of IN cord-005646-xhx9pzhj 1992 18 variables variable NNS cord-005646-xhx9pzhj 1992 19 ( ( -LRB- cord-005646-xhx9pzhj 1992 20 so so RB cord-005646-xhx9pzhj 1992 21 many many JJ cord-005646-xhx9pzhj 1992 22 ICUs icu NNS cord-005646-xhx9pzhj 1992 23 do do VBP cord-005646-xhx9pzhj 1992 24 not not RB cord-005646-xhx9pzhj 1992 25 calculate calculate VB cord-005646-xhx9pzhj 1992 26 them -PRON- PRP cord-005646-xhx9pzhj 1992 27 routinely routinely RB cord-005646-xhx9pzhj 1992 28 ) ) -RRB- cord-005646-xhx9pzhj 1992 29 , , , cord-005646-xhx9pzhj 1992 30 and and CC cord-005646-xhx9pzhj 1992 31 they -PRON- PRP cord-005646-xhx9pzhj 1992 32 use use VBP cord-005646-xhx9pzhj 1992 33 the the DT cord-005646-xhx9pzhj 1992 34 worst bad JJS cord-005646-xhx9pzhj 1992 35 value value NN cord-005646-xhx9pzhj 1992 36 of of IN cord-005646-xhx9pzhj 1992 37 each each DT cord-005646-xhx9pzhj 1992 38 variable variable NN cord-005646-xhx9pzhj 1992 39 in in IN cord-005646-xhx9pzhj 1992 40 the the DT cord-005646-xhx9pzhj 1992 41 first first JJ cord-005646-xhx9pzhj 1992 42 24 24 CD cord-005646-xhx9pzhj 1992 43 hours hour NNS cord-005646-xhx9pzhj 1992 44 in in IN cord-005646-xhx9pzhj 1992 45 intensive intensive JJ cord-005646-xhx9pzhj 1992 46 care care NN cord-005646-xhx9pzhj 1992 47 . . . cord-005646-xhx9pzhj 1993 1 This this DT cord-005646-xhx9pzhj 1993 2 means mean VBZ cord-005646-xhx9pzhj 1993 3 they -PRON- PRP cord-005646-xhx9pzhj 1993 4 appear appear VBP cord-005646-xhx9pzhj 1993 5 to to TO cord-005646-xhx9pzhj 1993 6 be be VB cord-005646-xhx9pzhj 1993 7 more more RBR cord-005646-xhx9pzhj 1993 8 accurate accurate JJ cord-005646-xhx9pzhj 1993 9 than than IN cord-005646-xhx9pzhj 1993 10 they -PRON- PRP cord-005646-xhx9pzhj 1993 11 really really RB cord-005646-xhx9pzhj 1993 12 are be VBP cord-005646-xhx9pzhj 1993 13 ( ( -LRB- cord-005646-xhx9pzhj 1994 1 about about RB cord-005646-xhx9pzhj 1994 2 40 40 CD cord-005646-xhx9pzhj 1994 3 % % NN cord-005646-xhx9pzhj 1994 4 of of IN cord-005646-xhx9pzhj 1994 5 child child NN cord-005646-xhx9pzhj 1994 6 deaths death NNS cord-005646-xhx9pzhj 1994 7 in in IN cord-005646-xhx9pzhj 1994 8 ICU ICU NNP cord-005646-xhx9pzhj 1994 9 occur occur VBP cord-005646-xhx9pzhj 1994 10 in in IN cord-005646-xhx9pzhj 1994 11 the the DT cord-005646-xhx9pzhj 1994 12 first first JJ cord-005646-xhx9pzhj 1994 13 24 24 CD cord-005646-xhx9pzhj 1994 14 hours hour NNS cord-005646-xhx9pzhj 1994 15 -so -so . cord-005646-xhx9pzhj 1995 1 they -PRON- PRP cord-005646-xhx9pzhj 1995 2 are be VBP cord-005646-xhx9pzhj 1995 3 diagnosing diagnose VBG cord-005646-xhx9pzhj 1995 4 these these DT cord-005646-xhx9pzhj 1995 5 deaths death NNS cord-005646-xhx9pzhj 1995 6 rather rather RB cord-005646-xhx9pzhj 1995 7 than than IN cord-005646-xhx9pzhj 1995 8 predicting predict VBG cord-005646-xhx9pzhj 1995 9 them -PRON- PRP cord-005646-xhx9pzhj 1995 10 ) ) -RRB- cord-005646-xhx9pzhj 1995 11 , , , cord-005646-xhx9pzhj 1995 12 and and CC cord-005646-xhx9pzhj 1995 13 they -PRON- PRP cord-005646-xhx9pzhj 1995 14 blurr blurr VBP cord-005646-xhx9pzhj 1995 15 the the DT cord-005646-xhx9pzhj 1995 16 differences difference NNS cord-005646-xhx9pzhj 1995 17 between between IN cord-005646-xhx9pzhj 1995 18 traits trait NNS cord-005646-xhx9pzhj 1995 19 ( ( -LRB- cord-005646-xhx9pzhj 1995 20 a a DT cord-005646-xhx9pzhj 1995 21 child child NN cord-005646-xhx9pzhj 1995 22 admitted admit VBN cord-005646-xhx9pzhj 1995 23 to to IN cord-005646-xhx9pzhj 1995 24 a a DT cord-005646-xhx9pzhj 1995 25 good good JJ cord-005646-xhx9pzhj 1995 26 unit unit NN cord-005646-xhx9pzhj 1995 27 who who WP cord-005646-xhx9pzhj 1995 28 recovers recover VBZ cord-005646-xhx9pzhj 1995 29 will will MD cord-005646-xhx9pzhj 1995 30 have have VB cord-005646-xhx9pzhj 1995 31 a a DT cord-005646-xhx9pzhj 1995 32 low low JJ cord-005646-xhx9pzhj 1995 33 score score NN cord-005646-xhx9pzhj 1995 34 ; ; : cord-005646-xhx9pzhj 1995 35 but but CC cord-005646-xhx9pzhj 1995 36 the the DT cord-005646-xhx9pzhj 1995 37 same same JJ cord-005646-xhx9pzhj 1995 38 child child NN cord-005646-xhx9pzhj 1995 39 who who WP cord-005646-xhx9pzhj 1995 40 is be VBZ cord-005646-xhx9pzhj 1995 41 mismanaged mismanage VBN cord-005646-xhx9pzhj 1995 42 in in IN cord-005646-xhx9pzhj 1995 43 a a DT cord-005646-xhx9pzhj 1995 44 bad bad JJ cord-005646-xhx9pzhj 1995 45 unit unit NN cord-005646-xhx9pzhj 1995 46 will will MD cord-005646-xhx9pzhj 1995 47 have have VB cord-005646-xhx9pzhj 1995 48 a a DT cord-005646-xhx9pzhj 1995 49 high high JJ cord-005646-xhx9pzhj 1995 50 score score NN cord-005646-xhx9pzhj 1995 51 -the -the DT cord-005646-xhx9pzhj 1995 52 bad bad JJ cord-005646-xhx9pzhj 1995 53 unit unit NN cord-005646-xhx9pzhj 1995 54 's 's POS cord-005646-xhx9pzhj 1995 55 high high JJ cord-005646-xhx9pzhj 1995 56 mortality mortality NN cord-005646-xhx9pzhj 1995 57 rate rate NN cord-005646-xhx9pzhj 1995 58 will will MD cord-005646-xhx9pzhj 1995 59 be be VB cord-005646-xhx9pzhj 1995 60 incorrectly incorrectly RB cord-005646-xhx9pzhj 1995 61 attributed attribute VBN cord-005646-xhx9pzhj 1995 62 to to IN cord-005646-xhx9pzhj 1995 63 its -PRON- PRP$ cord-005646-xhx9pzhj 1995 64 having have VBG cord-005646-xhx9pzhj 1995 65 sicker sick JJR cord-005646-xhx9pzhj 1995 66 patients patient NNS cord-005646-xhx9pzhj 1995 67 ) ) -RRB- cord-005646-xhx9pzhj 1995 68 . . . cord-005646-xhx9pzhj 1996 1 PIM PIM NNP cord-005646-xhx9pzhj 1996 2 was be VBD cord-005646-xhx9pzhj 1996 3 developed develop VBN cord-005646-xhx9pzhj 1996 4 in in IN cord-005646-xhx9pzhj 1996 5 the the DT cord-005646-xhx9pzhj 1996 6 PICU PICU NNP cord-005646-xhx9pzhj 1996 7 at at IN cord-005646-xhx9pzhj 1996 8 the the DT cord-005646-xhx9pzhj 1996 9 Royal Royal NNP cord-005646-xhx9pzhj 1996 10 Children Children NNPS cord-005646-xhx9pzhj 1996 11 's 's POS cord-005646-xhx9pzhj 1996 12 Hospital Hospital NNP cord-005646-xhx9pzhj 1996 13 in in IN cord-005646-xhx9pzhj 1996 14 Melbourne Melbourne NNP cord-005646-xhx9pzhj 1996 15 , , , cord-005646-xhx9pzhj 1996 16 and and CC cord-005646-xhx9pzhj 1996 17 has have VBZ cord-005646-xhx9pzhj 1996 18 been be VBN cord-005646-xhx9pzhj 1996 19 tested test VBN cord-005646-xhx9pzhj 1996 20 in in IN cord-005646-xhx9pzhj 1996 21 six six CD cord-005646-xhx9pzhj 1996 22 other other JJ cord-005646-xhx9pzhj 1996 23 PICUs picu NNS cord-005646-xhx9pzhj 1996 24 in in IN cord-005646-xhx9pzhj 1996 25 Australia Australia NNP cord-005646-xhx9pzhj 1996 26 and and CC cord-005646-xhx9pzhj 1996 27 one one CD cord-005646-xhx9pzhj 1996 28 in in IN cord-005646-xhx9pzhj 1996 29 the the DT cord-005646-xhx9pzhj 1996 30 UK UK NNP cord-005646-xhx9pzhj 1996 31 . . . cord-005646-xhx9pzhj 1997 1 Objectives objective NNS cord-005646-xhx9pzhj 1997 2 : : : cord-005646-xhx9pzhj 1997 3 To to TO cord-005646-xhx9pzhj 1997 4 study study VB cord-005646-xhx9pzhj 1997 5 the the DT cord-005646-xhx9pzhj 1997 6 characteristics characteristic NNS cord-005646-xhx9pzhj 1997 7 of of IN cord-005646-xhx9pzhj 1997 8 the the DT cord-005646-xhx9pzhj 1997 9 muhiorgan muhiorgan NNP cord-005646-xhx9pzhj 1997 10 dysfunction dysfunction NNP cord-005646-xhx9pzhj 1997 11 syndrome syndrome NN cord-005646-xhx9pzhj 1997 12 ( ( -LRB- cord-005646-xhx9pzhj 1997 13 MDS MDS NNP cord-005646-xhx9pzhj 1997 14 ) ) -RRB- cord-005646-xhx9pzhj 1997 15 in in IN cord-005646-xhx9pzhj 1997 16 children child NNS cord-005646-xhx9pzhj 1997 17 . . . cord-005646-xhx9pzhj 1998 1 Methods method NNS cord-005646-xhx9pzhj 1998 2 : : : cord-005646-xhx9pzhj 1999 1 A a DT cord-005646-xhx9pzhj 1999 2 retrospective retrospective JJ cord-005646-xhx9pzhj 1999 3 study study NN cord-005646-xhx9pzhj 1999 4 with with IN cord-005646-xhx9pzhj 1999 5 all all PDT cord-005646-xhx9pzhj 1999 6 the the DT cord-005646-xhx9pzhj 1999 7 children child NNS cord-005646-xhx9pzhj 1999 8 with with IN cord-005646-xhx9pzhj 1999 9 MDS MDS NNP cord-005646-xhx9pzhj 1999 10 diagnosed diagnose VBN cord-005646-xhx9pzhj 1999 11 from from IN cord-005646-xhx9pzhj 1999 12 January January NNP cord-005646-xhx9pzhj 1999 13 1990 1990 CD cord-005646-xhx9pzhj 1999 14 to to IN cord-005646-xhx9pzhj 1999 15 June June NNP cord-005646-xhx9pzhj 1999 16 1995 1995 CD cord-005646-xhx9pzhj 1999 17 is be VBZ cord-005646-xhx9pzhj 1999 18 presented present VBN cord-005646-xhx9pzhj 1999 19 . . . cord-005646-xhx9pzhj 2000 1 173 173 CD cord-005646-xhx9pzhj 2000 2 children child NNS cord-005646-xhx9pzhj 2000 3 fulfilled fulfil VBD cord-005646-xhx9pzhj 2000 4 the the DT cord-005646-xhx9pzhj 2000 5 Wilkinson Wilkinson NNP cord-005646-xhx9pzhj 2000 6 criteria criterion NNS cord-005646-xhx9pzhj 2000 7 ( ( -LRB- cord-005646-xhx9pzhj 2000 8 I i NN cord-005646-xhx9pzhj 2000 9 ) ) -RRB- cord-005646-xhx9pzhj 2000 10 . . . cord-005646-xhx9pzhj 2001 1 In in IN cord-005646-xhx9pzhj 2001 2 all all DT cord-005646-xhx9pzhj 2001 3 of of IN cord-005646-xhx9pzhj 2001 4 them -PRON- PRP cord-005646-xhx9pzhj 2001 5 the the DT cord-005646-xhx9pzhj 2001 6 number number NN cord-005646-xhx9pzhj 2001 7 of of IN cord-005646-xhx9pzhj 2001 8 organs organ NNS cord-005646-xhx9pzhj 2001 9 affected affect VBN cord-005646-xhx9pzhj 2001 10 and and CC cord-005646-xhx9pzhj 2001 11 the the DT cord-005646-xhx9pzhj 2001 12 PRIMS PRIMS NNP cord-005646-xhx9pzhj 2001 13 score score NN cord-005646-xhx9pzhj 2001 14 were be VBD cord-005646-xhx9pzhj 2001 15 determined determine VBN cord-005646-xhx9pzhj 2001 16 during during IN cord-005646-xhx9pzhj 2001 17 the the DT cord-005646-xhx9pzhj 2001 18 first first JJ cord-005646-xhx9pzhj 2001 19 24 24 CD cord-005646-xhx9pzhj 2001 20 hours hour NNS cord-005646-xhx9pzhj 2001 21 . . . cord-005646-xhx9pzhj 2002 1 Several several JJ cord-005646-xhx9pzhj 2002 2 groups group NNS cord-005646-xhx9pzhj 2002 3 were be VBD cord-005646-xhx9pzhj 2002 4 performed perform VBN cord-005646-xhx9pzhj 2002 5 according accord VBG cord-005646-xhx9pzhj 2002 6 to to IN cord-005646-xhx9pzhj 2002 7 the the DT cord-005646-xhx9pzhj 2002 8 clinical clinical JJ cord-005646-xhx9pzhj 2002 9 diagnosis diagnosis NN cord-005646-xhx9pzhj 2002 10 , , , cord-005646-xhx9pzhj 2002 11 the the DT cord-005646-xhx9pzhj 2002 12 hospital hospital NN cord-005646-xhx9pzhj 2002 13 of of IN cord-005646-xhx9pzhj 2002 14 origin origin NN cord-005646-xhx9pzhj 2002 15 and and CC cord-005646-xhx9pzhj 2002 16 the the DT cord-005646-xhx9pzhj 2002 17 order order NN cord-005646-xhx9pzhj 2002 18 of of IN cord-005646-xhx9pzhj 2002 19 organs organ NNS cord-005646-xhx9pzhj 2002 20 affected affect VBN cord-005646-xhx9pzhj 2002 21 . . . cord-005646-xhx9pzhj 2003 1 Results result NNS cord-005646-xhx9pzhj 2003 2 : : : cord-005646-xhx9pzhj 2004 1 The the DT cord-005646-xhx9pzhj 2004 2 173 173 CD cord-005646-xhx9pzhj 2004 3 subjects subject NNS cord-005646-xhx9pzhj 2004 4 studied study VBN cord-005646-xhx9pzhj 2004 5 were be VBD cord-005646-xhx9pzhj 2004 6 an an DT cord-005646-xhx9pzhj 2004 7 8 8 CD cord-005646-xhx9pzhj 2004 8 % % NN cord-005646-xhx9pzhj 2004 9 of of IN cord-005646-xhx9pzhj 2004 10 the the DT cord-005646-xhx9pzhj 2004 11 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2004 12 Intensive Intensive NNP cord-005646-xhx9pzhj 2004 13 Care Care NNP cord-005646-xhx9pzhj 2004 14 Unit Unit NNP cord-005646-xhx9pzhj 2004 15 admissions admission NNS cord-005646-xhx9pzhj 2004 16 . . . cord-005646-xhx9pzhj 2005 1 100 100 CD cord-005646-xhx9pzhj 2005 2 of of IN cord-005646-xhx9pzhj 2005 3 them -PRON- PRP cord-005646-xhx9pzhj 2005 4 expired expire VBD cord-005646-xhx9pzhj 2005 5 ( ( -LRB- cord-005646-xhx9pzhj 2005 6 58 58 CD cord-005646-xhx9pzhj 2005 7 % % NN cord-005646-xhx9pzhj 2005 8 ) ) -RRB- cord-005646-xhx9pzhj 2005 9 . . . cord-005646-xhx9pzhj 2006 1 No no DT cord-005646-xhx9pzhj 2006 2 differences difference NNS cord-005646-xhx9pzhj 2006 3 in in IN cord-005646-xhx9pzhj 2006 4 age age NN cord-005646-xhx9pzhj 2006 5 , , , cord-005646-xhx9pzhj 2006 6 sex sex NN cord-005646-xhx9pzhj 2006 7 and and CC cord-005646-xhx9pzhj 2006 8 weight weight NN cord-005646-xhx9pzhj 2006 9 were be VBD cord-005646-xhx9pzhj 2006 10 observed observe VBN cord-005646-xhx9pzhj 2006 11 between between IN cord-005646-xhx9pzhj 2006 12 the the DT cord-005646-xhx9pzhj 2006 13 children child NNS cord-005646-xhx9pzhj 2006 14 dying die VBG cord-005646-xhx9pzhj 2006 15 and and CC cord-005646-xhx9pzhj 2006 16 the the DT cord-005646-xhx9pzhj 2006 17 survivals survival NNS cord-005646-xhx9pzhj 2006 18 . . . cord-005646-xhx9pzhj 2007 1 The the DT cord-005646-xhx9pzhj 2007 2 most most RBS cord-005646-xhx9pzhj 2007 3 common common JJ cord-005646-xhx9pzhj 2007 4 causes cause NNS cord-005646-xhx9pzhj 2007 5 of of IN cord-005646-xhx9pzhj 2007 6 MDS MDS NNP cord-005646-xhx9pzhj 2007 7 were be VBD cord-005646-xhx9pzhj 2007 8 sepsis sepsis NN cord-005646-xhx9pzhj 2007 9 , , , cord-005646-xhx9pzhj 2007 10 both both DT cord-005646-xhx9pzhj 2007 11 nosocomial nosocomial JJ cord-005646-xhx9pzhj 2007 12 ( ( -LRB- cord-005646-xhx9pzhj 2007 13 25 25 CD cord-005646-xhx9pzhj 2007 14 % % NN cord-005646-xhx9pzhj 2007 15 ) ) -RRB- cord-005646-xhx9pzhj 2007 16 and and CC cord-005646-xhx9pzhj 2007 17 medingococcal medingococcal JJ cord-005646-xhx9pzhj 2007 18 ( ( -LRB- cord-005646-xhx9pzhj 2007 19 I4 I4 NNP cord-005646-xhx9pzhj 2007 20 % % NN cord-005646-xhx9pzhj 2007 21 ) ) -RRB- cord-005646-xhx9pzhj 2007 22 and and CC cord-005646-xhx9pzhj 2007 23 acute acute JJ cord-005646-xhx9pzhj 2007 24 respiratory respiratory JJ cord-005646-xhx9pzhj 2007 25 failure failure NN cord-005646-xhx9pzhj 2007 26 . . . cord-005646-xhx9pzhj 2008 1 Sixty sixty JJ cord-005646-xhx9pzhj 2008 2 - - HYPH cord-005646-xhx9pzhj 2008 3 fivepercent fivepercent NN cord-005646-xhx9pzhj 2008 4 of of IN cord-005646-xhx9pzhj 2008 5 the the DT cord-005646-xhx9pzhj 2008 6 patients patient NNS cord-005646-xhx9pzhj 2008 7 were be VBD cord-005646-xhx9pzhj 2008 8 from from IN cord-005646-xhx9pzhj 2008 9 the the DT cord-005646-xhx9pzhj 2008 10 hospital hospital NN cord-005646-xhx9pzhj 2008 11 wards ward NNS cord-005646-xhx9pzhj 2008 12 and and CC cord-005646-xhx9pzhj 2008 13 the the DT cord-005646-xhx9pzhj 2008 14 remaining remain VBG cord-005646-xhx9pzhj 2008 15 were be VBD cord-005646-xhx9pzhj 2008 16 directly directly RB cord-005646-xhx9pzhj 2008 17 admitted admit VBN cord-005646-xhx9pzhj 2008 18 to to IN cord-005646-xhx9pzhj 2008 19 the the DT cord-005646-xhx9pzhj 2008 20 PIGU PIGU NNP cord-005646-xhx9pzhj 2008 21 from from IN cord-005646-xhx9pzhj 2008 22 the the DT cord-005646-xhx9pzhj 2008 23 Emergency Emergency NNP cord-005646-xhx9pzhj 2008 24 room room NN cord-005646-xhx9pzhj 2008 25 . . . cord-005646-xhx9pzhj 2009 1 The the DT cord-005646-xhx9pzhj 2009 2 systems system NNS cord-005646-xhx9pzhj 2009 3 affected affect VBN cord-005646-xhx9pzhj 2009 4 were be VBD cord-005646-xhx9pzhj 2009 5 : : : cord-005646-xhx9pzhj 2009 6 respiratory respiratory JJ cord-005646-xhx9pzhj 2009 7 ( ( -LRB- cord-005646-xhx9pzhj 2009 8 93 93 CD cord-005646-xhx9pzhj 2009 9 % % NN cord-005646-xhx9pzhj 2009 10 ) ) -RRB- cord-005646-xhx9pzhj 2009 11 , , , cord-005646-xhx9pzhj 2009 12 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 2009 13 ( ( -LRB- cord-005646-xhx9pzhj 2009 14 92 92 CD cord-005646-xhx9pzhj 2009 15 % % NN cord-005646-xhx9pzhj 2009 16 ) ) -RRB- cord-005646-xhx9pzhj 2009 17 , , , cord-005646-xhx9pzhj 2009 18 hematologic hematologic JJ cord-005646-xhx9pzhj 2009 19 ( ( -LRB- cord-005646-xhx9pzhj 2009 20 61 61 CD cord-005646-xhx9pzhj 2009 21 % % NN cord-005646-xhx9pzhj 2009 22 ) ) -RRB- cord-005646-xhx9pzhj 2009 23 , , , cord-005646-xhx9pzhj 2009 24 central central JJ cord-005646-xhx9pzhj 2009 25 nervous nervous JJ cord-005646-xhx9pzhj 2009 26 system system NN cord-005646-xhx9pzhj 2009 27 ( ( -LRB- cord-005646-xhx9pzhj 2009 28 52 52 CD cord-005646-xhx9pzhj 2009 29 % % NN cord-005646-xhx9pzhj 2009 30 ) ) -RRB- cord-005646-xhx9pzhj 2009 31 , , . cord-005646-xhx9pzhj 2010 1 renal renal JJ cord-005646-xhx9pzhj 2010 2 ( ( -LRB- cord-005646-xhx9pzhj 2010 3 43 43 CD cord-005646-xhx9pzhj 2010 4 % % NN cord-005646-xhx9pzhj 2010 5 ) ) -RRB- cord-005646-xhx9pzhj 2010 6 and and CC cord-005646-xhx9pzhj 2010 7 ( ( -LRB- cord-005646-xhx9pzhj 2010 8 hepatic hepatic JJ cord-005646-xhx9pzhj 2010 9 ) ) -RRB- cord-005646-xhx9pzhj 2010 10 liver liver NN cord-005646-xhx9pzhj 2010 11 ( ( -LRB- cord-005646-xhx9pzhj 2010 12 28 28 CD cord-005646-xhx9pzhj 2010 13 % % NN cord-005646-xhx9pzhj 2010 14 ) ) -RRB- cord-005646-xhx9pzhj 2010 15 . . . cord-005646-xhx9pzhj 2011 1 The the DT cord-005646-xhx9pzhj 2011 2 organs organ NNS cord-005646-xhx9pzhj 2011 3 initially initially RB cord-005646-xhx9pzhj 2011 4 failing fail VBG cord-005646-xhx9pzhj 2011 5 were be VBD cord-005646-xhx9pzhj 2011 6 : : : cord-005646-xhx9pzhj 2011 7 heart heart NN cord-005646-xhx9pzhj 2011 8 ( ( -LRB- cord-005646-xhx9pzhj 2011 9 39 39 CD cord-005646-xhx9pzhj 2011 10 % % NN cord-005646-xhx9pzhj 2011 11 ) ) -RRB- cord-005646-xhx9pzhj 2011 12 , , , cord-005646-xhx9pzhj 2011 13 tung tung NNP cord-005646-xhx9pzhj 2011 14 ( ( -LRB- cord-005646-xhx9pzhj 2011 15 28 28 CD cord-005646-xhx9pzhj 2011 16 % % NN cord-005646-xhx9pzhj 2011 17 ) ) -RRB- cord-005646-xhx9pzhj 2011 18 and and CC cord-005646-xhx9pzhj 2011 19 central central JJ cord-005646-xhx9pzhj 2011 20 nervous nervous JJ cord-005646-xhx9pzhj 2011 21 system system NN cord-005646-xhx9pzhj 2011 22 ( ( -LRB- cord-005646-xhx9pzhj 2011 23 18 18 CD cord-005646-xhx9pzhj 2011 24 % % NN cord-005646-xhx9pzhj 2011 25 ) ) -RRB- cord-005646-xhx9pzhj 2011 26 . . . cord-005646-xhx9pzhj 2012 1 The the DT cord-005646-xhx9pzhj 2012 2 children child NNS cord-005646-xhx9pzhj 2012 3 dying die VBG cord-005646-xhx9pzhj 2012 4 had have VBD cord-005646-xhx9pzhj 2012 5 a a DT cord-005646-xhx9pzhj 2012 6 larger large JJR cord-005646-xhx9pzhj 2012 7 number number NN cord-005646-xhx9pzhj 2012 8 of of IN cord-005646-xhx9pzhj 2012 9 organs organ NNS cord-005646-xhx9pzhj 2012 10 with with IN cord-005646-xhx9pzhj 2012 11 failure failure NN cord-005646-xhx9pzhj 2012 12 than than IN cord-005646-xhx9pzhj 2012 13 the the DT cord-005646-xhx9pzhj 2012 14 survivors survivor NNS cord-005646-xhx9pzhj 2012 15 ( ( -LRB- cord-005646-xhx9pzhj 2012 16 3.89 3.89 CD cord-005646-xhx9pzhj 2012 17 v v NN cord-005646-xhx9pzhj 2012 18 , , , cord-005646-xhx9pzhj 2012 19 s s NNP cord-005646-xhx9pzhj 2012 20 . . NNP cord-005646-xhx9pzhj 2012 21 3.34 3.34 CD cord-005646-xhx9pzhj 2012 22 , , , cord-005646-xhx9pzhj 2012 23 p<0.001).The p<0.001).The NNP cord-005646-xhx9pzhj 2012 24 PRMIS prmi NNS cord-005646-xhx9pzhj 2012 25 score score NN cord-005646-xhx9pzhj 2012 26 was be VBD cord-005646-xhx9pzhj 2012 27 higher high JJR cord-005646-xhx9pzhj 2012 28 in in IN cord-005646-xhx9pzhj 2012 29 the the DT cord-005646-xhx9pzhj 2012 30 children child NNS cord-005646-xhx9pzhj 2012 31 expiring expire VBG cord-005646-xhx9pzhj 2012 32 than than IN cord-005646-xhx9pzhj 2012 33 in in IN cord-005646-xhx9pzhj 2012 34 the the DT cord-005646-xhx9pzhj 2012 35 survivors survivor NNS cord-005646-xhx9pzhj 2012 36 ( ( -LRB- cord-005646-xhx9pzhj 2012 37 22.4 22.4 CD cord-005646-xhx9pzhj 2012 38 v.s. v.s. NNP cord-005646-xhx9pzhj 2012 39 17 17 CD cord-005646-xhx9pzhj 2012 40 , , , cord-005646-xhx9pzhj 2012 41 p p NN cord-005646-xhx9pzhj 2012 42 < < XX cord-005646-xhx9pzhj 2012 43 0.001 0.001 CD cord-005646-xhx9pzhj 2012 44 ) ) -RRB- cord-005646-xhx9pzhj 2012 45 . . . cord-005646-xhx9pzhj 2013 1 S.mmary S.mmary NNP cord-005646-xhx9pzhj 2013 2 : : : cord-005646-xhx9pzhj 2014 1 The the DT cord-005646-xhx9pzhj 2014 2 MDS MDS NNP cord-005646-xhx9pzhj 2014 3 is be VBZ cord-005646-xhx9pzhj 2014 4 a a DT cord-005646-xhx9pzhj 2014 5 common common JJ cord-005646-xhx9pzhj 2014 6 pathology pathology NN cord-005646-xhx9pzhj 2014 7 in in IN cord-005646-xhx9pzhj 2014 8 PICU PICU NNP cord-005646-xhx9pzhj 2014 9 , , , cord-005646-xhx9pzhj 2014 10 with with IN cord-005646-xhx9pzhj 2014 11 a a DT cord-005646-xhx9pzhj 2014 12 high high JJ cord-005646-xhx9pzhj 2014 13 mortality mortality NN cord-005646-xhx9pzhj 2014 14 , , , cord-005646-xhx9pzhj 2014 15 The the DT cord-005646-xhx9pzhj 2014 16 mortality mortality NN cord-005646-xhx9pzhj 2014 17 is be VBZ cord-005646-xhx9pzhj 2014 18 higher high JJR cord-005646-xhx9pzhj 2014 19 in in IN cord-005646-xhx9pzhj 2014 20 children child NNS cord-005646-xhx9pzhj 2014 21 with with IN cord-005646-xhx9pzhj 2014 22 a a DT cord-005646-xhx9pzhj 2014 23 larger large JJR cord-005646-xhx9pzhj 2014 24 number number NN cord-005646-xhx9pzhj 2014 25 of of IN cord-005646-xhx9pzhj 2014 26 organs organ NNS cord-005646-xhx9pzhj 2014 27 affected affect VBN cord-005646-xhx9pzhj 2014 28 and and CC cord-005646-xhx9pzhj 2014 29 a a DT cord-005646-xhx9pzhj 2014 30 higher high JJR cord-005646-xhx9pzhj 2014 31 PRISM prism NN cord-005646-xhx9pzhj 2014 32 score score NN cord-005646-xhx9pzhj 2014 33 . . . cord-005646-xhx9pzhj 2015 1 Sepsis sepsis NN cord-005646-xhx9pzhj 2015 2 is be VBZ cord-005646-xhx9pzhj 2015 3 the the DT cord-005646-xhx9pzhj 2015 4 most most RBS cord-005646-xhx9pzhj 2015 5 common common JJ cord-005646-xhx9pzhj 2015 6 etiulogy etiulogy NN cord-005646-xhx9pzhj 2015 7 . . . cord-005646-xhx9pzhj 2016 1 Methods method NNS cord-005646-xhx9pzhj 2016 2 : : : cord-005646-xhx9pzhj 2017 1 From from IN cord-005646-xhx9pzhj 2017 2 June June NNP cord-005646-xhx9pzhj 2017 3 Ist Ist NNP cord-005646-xhx9pzhj 2017 4 to to IN cord-005646-xhx9pzhj 2017 5 July July NNP cord-005646-xhx9pzhj 2017 6 15th 15th NN cord-005646-xhx9pzhj 2017 7 1995 1995 CD cord-005646-xhx9pzhj 2017 8 , , , cord-005646-xhx9pzhj 2017 9 all all DT cord-005646-xhx9pzhj 2017 10 patients patient NNS cord-005646-xhx9pzhj 2017 11 admitted admit VBD cord-005646-xhx9pzhj 2017 12 to to IN cord-005646-xhx9pzhj 2017 13 the the DT cord-005646-xhx9pzhj 2017 14 pediatric pediatric JJ cord-005646-xhx9pzhj 2017 15 ICU ICU NNP cord-005646-xhx9pzhj 2017 16 were be VBD cord-005646-xhx9pzhj 2017 17 included include VBN cord-005646-xhx9pzhj 2017 18 . . . cord-005646-xhx9pzhj 2018 1 The the DT cord-005646-xhx9pzhj 2018 2 score score NN cord-005646-xhx9pzhj 2018 3 was be VBD cord-005646-xhx9pzhj 2018 4 measured measure VBN cord-005646-xhx9pzhj 2018 5 at at IN cord-005646-xhx9pzhj 2018 6 day day NN cord-005646-xhx9pzhj 2018 7 1 1 CD cord-005646-xhx9pzhj 2018 8 ( ( -LRB- cord-005646-xhx9pzhj 2018 9 D1 D1 NNP cord-005646-xhx9pzhj 2018 10 ) ) -RRB- cord-005646-xhx9pzhj 2018 11 and and CC cord-005646-xhx9pzhj 2018 12 day day NN cord-005646-xhx9pzhj 2018 13 3 3 CD cord-005646-xhx9pzhj 2018 14 ( ( -LRB- cord-005646-xhx9pzhj 2018 15 D3 D3 NNP cord-005646-xhx9pzhj 2018 16 ) ) -RRB- cord-005646-xhx9pzhj 2019 1 and and CC cord-005646-xhx9pzhj 2019 2 we -PRON- PRP cord-005646-xhx9pzhj 2019 3 used use VBD cord-005646-xhx9pzhj 2019 4 10 10 CD cord-005646-xhx9pzhj 2019 5 variables variable NNS cord-005646-xhx9pzhj 2019 6 . . . cord-005646-xhx9pzhj 2020 1 For for IN cord-005646-xhx9pzhj 2020 2 each each DT cord-005646-xhx9pzhj 2020 3 organ organ NN cord-005646-xhx9pzhj 2020 4 system system NN cord-005646-xhx9pzhj 2020 5 , , , cord-005646-xhx9pzhj 2020 6 we -PRON- PRP cord-005646-xhx9pzhj 2020 7 defined define VBD cord-005646-xhx9pzhj 2020 8 2 2 CD cord-005646-xhx9pzhj 2020 9 categories category NNS cord-005646-xhx9pzhj 2020 10 : : : cord-005646-xhx9pzhj 2020 11 dysfunction dysfunction NN cord-005646-xhx9pzhj 2020 12 or or CC cord-005646-xhx9pzhj 2020 13 failure failure NN cord-005646-xhx9pzhj 2020 14 , , , cord-005646-xhx9pzhj 2020 15 which which WDT cord-005646-xhx9pzhj 2020 16 we -PRON- PRP cord-005646-xhx9pzhj 2020 17 respectively respectively RB cord-005646-xhx9pzhj 2020 18 confered confer VBD cord-005646-xhx9pzhj 2020 19 1 1 CD cord-005646-xhx9pzhj 2020 20 or or CC cord-005646-xhx9pzhj 2020 21 4 4 CD cord-005646-xhx9pzhj 2020 22 points point NNS cord-005646-xhx9pzhj 2020 23 . . . cord-005646-xhx9pzhj 2021 1 Results result NNS cord-005646-xhx9pzhj 2021 2 : : : cord-005646-xhx9pzhj 2021 3 56 56 CD cord-005646-xhx9pzhj 2021 4 patients patient NNS cord-005646-xhx9pzhj 2021 5 were be VBD cord-005646-xhx9pzhj 2021 6 admitted admit VBN cord-005646-xhx9pzhj 2021 7 : : : cord-005646-xhx9pzhj 2021 8 22 22 CD cord-005646-xhx9pzhj 2021 9 newborns newborn NNS cord-005646-xhx9pzhj 2021 10 , , , cord-005646-xhx9pzhj 2021 11 34 34 CD cord-005646-xhx9pzhj 2021 12 children child NNS cord-005646-xhx9pzhj 2021 13 . . . cord-005646-xhx9pzhj 2022 1 23 23 CD cord-005646-xhx9pzhj 2022 2 were be VBD cord-005646-xhx9pzhj 2022 3 medical medical JJ cord-005646-xhx9pzhj 2022 4 and and CC cord-005646-xhx9pzhj 2022 5 33 33 CD cord-005646-xhx9pzhj 2022 6 were be VBD cord-005646-xhx9pzhj 2022 7 surgical surgical JJ cord-005646-xhx9pzhj 2022 8 patients patient NNS cord-005646-xhx9pzhj 2022 9 . . . cord-005646-xhx9pzhj 2023 1 36 36 CD cord-005646-xhx9pzhj 2023 2 ( ( -LRB- cord-005646-xhx9pzhj 2023 3 64 64 CD cord-005646-xhx9pzhj 2023 4 % % NN cord-005646-xhx9pzhj 2023 5 ) ) -RRB- cord-005646-xhx9pzhj 2023 6 patients patient NNS cord-005646-xhx9pzhj 2023 7 had have VBD cord-005646-xhx9pzhj 2023 8 two two CD cord-005646-xhx9pzhj 2023 9 or or CC cord-005646-xhx9pzhj 2023 10 more more JJR cord-005646-xhx9pzhj 2023 11 organ organ NN cord-005646-xhx9pzhj 2023 12 failure failure NN cord-005646-xhx9pzhj 2023 13 at at IN cord-005646-xhx9pzhj 2023 14 the the DT cord-005646-xhx9pzhj 2023 15 admission admission NN cord-005646-xhx9pzhj 2023 16 , , , cord-005646-xhx9pzhj 2023 17 12 12 CD cord-005646-xhx9pzhj 2023 18 ( ( -LRB- cord-005646-xhx9pzhj 2023 19 21,4 21,4 CD cord-005646-xhx9pzhj 2023 20 % % NN cord-005646-xhx9pzhj 2023 21 ) ) -RRB- cord-005646-xhx9pzhj 2023 22 patients patient NNS cord-005646-xhx9pzhj 2023 23 died die VBD cord-005646-xhx9pzhj 2023 24 , , , cord-005646-xhx9pzhj 2023 25 which which WDT cord-005646-xhx9pzhj 2023 26 6 6 CD cord-005646-xhx9pzhj 2023 27 ( ( -LRB- cord-005646-xhx9pzhj 2023 28 50 50 CD cord-005646-xhx9pzhj 2023 29 % % NN cord-005646-xhx9pzhj 2023 30 ) ) -RRB- cord-005646-xhx9pzhj 2023 31 in in IN cord-005646-xhx9pzhj 2023 32 the the DT cord-005646-xhx9pzhj 2023 33 first first JJ cord-005646-xhx9pzhj 2023 34 48 48 CD cord-005646-xhx9pzhj 2023 35 hours hour NNS cord-005646-xhx9pzhj 2023 36 . . . cord-005646-xhx9pzhj 2024 1 The the DT cord-005646-xhx9pzhj 2024 2 mortality mortality NN cord-005646-xhx9pzhj 2024 3 rate rate NN cord-005646-xhx9pzhj 2024 4 was be VBD cord-005646-xhx9pzhj 2024 5 the the DT cord-005646-xhx9pzhj 2024 6 same same JJ cord-005646-xhx9pzhj 2024 7 for for IN cord-005646-xhx9pzhj 2024 8 children child NNS cord-005646-xhx9pzhj 2024 9 with with IN cord-005646-xhx9pzhj 2024 10 two two CD cord-005646-xhx9pzhj 2024 11 or or CC cord-005646-xhx9pzhj 2024 12 more more JJR cord-005646-xhx9pzhj 2024 13 organ organ NN cord-005646-xhx9pzhj 2025 1 faiIure faiiure NN cord-005646-xhx9pzhj 2025 2 at at IN cord-005646-xhx9pzhj 2025 3 D1 d1 NN cord-005646-xhx9pzhj 2025 4 and and CC cord-005646-xhx9pzhj 2025 5 D3 D3 NNP cord-005646-xhx9pzhj 2025 6 : : : cord-005646-xhx9pzhj 2025 7 6/36 6/36 NNP cord-005646-xhx9pzhj 2025 8 ( ( -LRB- cord-005646-xhx9pzhj 2025 9 16,6 16,6 CD cord-005646-xhx9pzhj 2025 10 % % NN cord-005646-xhx9pzhj 2025 11 ) ) -RRB- cord-005646-xhx9pzhj 2025 12 at at IN cord-005646-xhx9pzhj 2025 13 D1 d1 NN cord-005646-xhx9pzhj 2025 14 , , , cord-005646-xhx9pzhj 2025 15 4/22 4/22 CD cord-005646-xhx9pzhj 2025 16 ( ( -LRB- cord-005646-xhx9pzhj 2025 17 18,2 18,2 CD cord-005646-xhx9pzhj 2025 18 % % NN cord-005646-xhx9pzhj 2025 19 ) ) -RRB- cord-005646-xhx9pzhj 2025 20 at at IN cord-005646-xhx9pzhj 2025 21 D3 D3 NNP cord-005646-xhx9pzhj 2025 22 . . . cord-005646-xhx9pzhj 2026 1 The the DT cord-005646-xhx9pzhj 2026 2 mean mean JJ cord-005646-xhx9pzhj 2026 3 score score NN cord-005646-xhx9pzhj 2026 4 is be VBZ cord-005646-xhx9pzhj 2026 5 different different JJ cord-005646-xhx9pzhj 2026 6 for for IN cord-005646-xhx9pzhj 2026 7 children child NNS cord-005646-xhx9pzhj 2026 8 who who WP cord-005646-xhx9pzhj 2026 9 survived survive VBD cord-005646-xhx9pzhj 2026 10 or or CC cord-005646-xhx9pzhj 2026 11 who who WP cord-005646-xhx9pzhj 2026 12 died die VBD cord-005646-xhx9pzhj 2026 13 : : : cord-005646-xhx9pzhj 2026 14 8,6 8,6 CD cord-005646-xhx9pzhj 2026 15 versus versus IN cord-005646-xhx9pzhj 2026 16 17,9 17,9 CD cord-005646-xhx9pzhj 2026 17 at at IN cord-005646-xhx9pzhj 2026 18 D1 d1 NN cord-005646-xhx9pzhj 2026 19 ; ; : cord-005646-xhx9pzhj 2026 20 10,6 10,6 CD cord-005646-xhx9pzhj 2026 21 versus versus IN cord-005646-xhx9pzhj 2026 22 18,2 18,2 CD cord-005646-xhx9pzhj 2026 23 at at IN cord-005646-xhx9pzhj 2026 24 133 133 CD cord-005646-xhx9pzhj 2026 25 . . . cord-005646-xhx9pzhj 2027 1 When when WRB cord-005646-xhx9pzhj 2027 2 the the DT cord-005646-xhx9pzhj 2027 3 score score NN cord-005646-xhx9pzhj 2027 4 is be VBZ cord-005646-xhx9pzhj 2027 5 > > XX cord-005646-xhx9pzhj 2027 6 15 15 CD cord-005646-xhx9pzhj 2027 7 , , , cord-005646-xhx9pzhj 2027 8 the the DT cord-005646-xhx9pzhj 2027 9 mortality mortality NN cord-005646-xhx9pzhj 2027 10 rate rate NN cord-005646-xhx9pzhj 2027 11 is be VBZ cord-005646-xhx9pzhj 2027 12 significant significant JJ cord-005646-xhx9pzhj 2027 13 . . . cord-005646-xhx9pzhj 2027 14 _SP cord-005646-xhx9pzhj 2028 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2028 2 : : : cord-005646-xhx9pzhj 2028 3 In in IN cord-005646-xhx9pzhj 2028 4 this this DT cord-005646-xhx9pzhj 2028 5 study study NN cord-005646-xhx9pzhj 2028 6 , , , cord-005646-xhx9pzhj 2028 7 there there EX cord-005646-xhx9pzhj 2028 8 is be VBZ cord-005646-xhx9pzhj 2028 9 a a DT cord-005646-xhx9pzhj 2028 10 good good JJ cord-005646-xhx9pzhj 2028 11 correlation correlation NN cord-005646-xhx9pzhj 2028 12 between between IN cord-005646-xhx9pzhj 2028 13 the the DT cord-005646-xhx9pzhj 2028 14 score score NN cord-005646-xhx9pzhj 2028 15 of of IN cord-005646-xhx9pzhj 2028 16 severity severity NN cord-005646-xhx9pzhj 2028 17 and and CC cord-005646-xhx9pzhj 2028 18 the the DT cord-005646-xhx9pzhj 2028 19 mortality mortality NN cord-005646-xhx9pzhj 2028 20 rate rate NN cord-005646-xhx9pzhj 2028 21 but but CC cord-005646-xhx9pzhj 2028 22 we -PRON- PRP cord-005646-xhx9pzhj 2028 23 have have VBP cord-005646-xhx9pzhj 2028 24 few few JJ cord-005646-xhx9pzhj 2028 25 included include VBN cord-005646-xhx9pzhj 2028 26 patients patient NNS cord-005646-xhx9pzhj 2028 27 . . . cord-005646-xhx9pzhj 2029 1 We -PRON- PRP cord-005646-xhx9pzhj 2029 2 need need VBP cord-005646-xhx9pzhj 2029 3 a a DT cord-005646-xhx9pzhj 2029 4 prospective prospective JJ cord-005646-xhx9pzhj 2029 5 multicentric multicentric NN cord-005646-xhx9pzhj 2029 6 study study NN cord-005646-xhx9pzhj 2029 7 to to TO cord-005646-xhx9pzhj 2029 8 assess assess VB cord-005646-xhx9pzhj 2029 9 these these DT cord-005646-xhx9pzhj 2029 10 results result NNS cord-005646-xhx9pzhj 2029 11 and and CC cord-005646-xhx9pzhj 2029 12 we -PRON- PRP cord-005646-xhx9pzhj 2029 13 must must MD cord-005646-xhx9pzhj 2029 14 compare compare VB cord-005646-xhx9pzhj 2029 15 this this DT cord-005646-xhx9pzhj 2029 16 score score NN cord-005646-xhx9pzhj 2029 17 to to IN cord-005646-xhx9pzhj 2029 18 other other JJ cord-005646-xhx9pzhj 2029 19 scores score NNS cord-005646-xhx9pzhj 2029 20 of of IN cord-005646-xhx9pzhj 2029 21 severity severity NN cord-005646-xhx9pzhj 2029 22 used use VBN cord-005646-xhx9pzhj 2029 23 in in IN cord-005646-xhx9pzhj 2029 24 PICU PICU NNP cord-005646-xhx9pzhj 2029 25 . . . cord-005646-xhx9pzhj 2030 1 Back.qround back.qround RB cord-005646-xhx9pzhj 2030 2 : : : cord-005646-xhx9pzhj 2031 1 Injury injury NN cord-005646-xhx9pzhj 2031 2 to to IN cord-005646-xhx9pzhj 2031 3 the the DT cord-005646-xhx9pzhj 2031 4 Central central JJ cord-005646-xhx9pzhj 2031 5 nervous nervous JJ cord-005646-xhx9pzhj 2031 6 system system NN cord-005646-xhx9pzhj 2031 7 is be VBZ cord-005646-xhx9pzhj 2031 8 the the DT cord-005646-xhx9pzhj 2031 9 cause cause NN cord-005646-xhx9pzhj 2031 10 of of IN cord-005646-xhx9pzhj 2031 11 death death NN cord-005646-xhx9pzhj 2031 12 in in IN cord-005646-xhx9pzhj 2031 13 the the DT cord-005646-xhx9pzhj 2031 14 majority majority NN cord-005646-xhx9pzhj 2031 15 of of IN cord-005646-xhx9pzhj 2031 16 pediatric pediatric JJ cord-005646-xhx9pzhj 2031 17 trauma trauma NN cord-005646-xhx9pzhj 2031 18 victims victim NNS cord-005646-xhx9pzhj 2031 19 , , , cord-005646-xhx9pzhj 2031 20 Studies study NNS cord-005646-xhx9pzhj 2031 21 have have VBP cord-005646-xhx9pzhj 2031 22 identified identify VBN cord-005646-xhx9pzhj 2031 23 a a DT cord-005646-xhx9pzhj 2031 24 wide wide JJ cord-005646-xhx9pzhj 2031 25 range range NN cord-005646-xhx9pzhj 2031 26 of of IN cord-005646-xhx9pzhj 2031 27 factors factor NNS cord-005646-xhx9pzhj 2031 28 associated associate VBN cord-005646-xhx9pzhj 2031 29 with with IN cord-005646-xhx9pzhj 2031 30 poor poor JJ cord-005646-xhx9pzhj 2031 31 outcome outcome NN cord-005646-xhx9pzhj 2031 32 from from IN cord-005646-xhx9pzhj 2031 33 brain brain NN cord-005646-xhx9pzhj 2031 34 injury injury NN cord-005646-xhx9pzhj 2031 35 . . . cord-005646-xhx9pzhj 2032 1 However however RB cord-005646-xhx9pzhj 2032 2 , , , cord-005646-xhx9pzhj 2032 3 when when WRB cord-005646-xhx9pzhj 2032 4 single single JJ cord-005646-xhx9pzhj 2032 5 features feature NNS cord-005646-xhx9pzhj 2032 6 are be VBP cord-005646-xhx9pzhj 2032 7 analyzed analyze VBN cord-005646-xhx9pzhj 2032 8 , , , cord-005646-xhx9pzhj 2032 9 they -PRON- PRP cord-005646-xhx9pzhj 2032 10 are be VBP cord-005646-xhx9pzhj 2032 11 not not RB cord-005646-xhx9pzhj 2032 12 sufficiently sufficiently RB cord-005646-xhx9pzhj 2032 13 accurate accurate JJ cord-005646-xhx9pzhj 2032 14 predictors predictor NNS cord-005646-xhx9pzhj 2032 15 . . . cord-005646-xhx9pzhj 2033 1 Few few JJ cord-005646-xhx9pzhj 2033 2 studies study NNS cord-005646-xhx9pzhj 2033 3 have have VBP cord-005646-xhx9pzhj 2033 4 used use VBN cord-005646-xhx9pzhj 2033 5 a a DT cord-005646-xhx9pzhj 2033 6 multivariate multivariate JJ cord-005646-xhx9pzhj 2033 7 analysis analysis NN cord-005646-xhx9pzhj 2033 8 of of IN cord-005646-xhx9pzhj 2033 9 these these DT cord-005646-xhx9pzhj 2033 10 factors factor NNS cord-005646-xhx9pzhj 2033 11 and and CC cord-005646-xhx9pzhj 2033 12 pediatric pediatric JJ cord-005646-xhx9pzhj 2033 13 outcome outcome NN cord-005646-xhx9pzhj 2033 14 , , , cord-005646-xhx9pzhj 2033 15 Methods method NNS cord-005646-xhx9pzhj 2033 16 : : : cord-005646-xhx9pzhj 2033 17 Clinical clinical JJ cord-005646-xhx9pzhj 2033 18 and and CC cord-005646-xhx9pzhj 2033 19 radiographic radiographic JJ cord-005646-xhx9pzhj 2033 20 features feature NNS cord-005646-xhx9pzhj 2033 21 of of IN cord-005646-xhx9pzhj 2033 22 164 164 CD cord-005646-xhx9pzhj 2033 23 comatose comatose JJ cord-005646-xhx9pzhj 2033 24 children child NNS cord-005646-xhx9pzhj 2033 25 after after IN cord-005646-xhx9pzhj 2033 26 traumatic traumatic JJ cord-005646-xhx9pzhj 2033 27 brain brain NN cord-005646-xhx9pzhj 2033 28 injury injury NN cord-005646-xhx9pzhj 2033 29 were be VBD cord-005646-xhx9pzhj 2033 30 analyzed analyze VBN cord-005646-xhx9pzhj 2033 31 , , , cord-005646-xhx9pzhj 2033 32 Clinical clinical JJ cord-005646-xhx9pzhj 2033 33 parameters parameter NNS cord-005646-xhx9pzhj 2033 34 , , , cord-005646-xhx9pzhj 2033 35 the the DT cord-005646-xhx9pzhj 2033 36 initial initial JJ cord-005646-xhx9pzhj 2033 37 cranial cranial JJ cord-005646-xhx9pzhj 2033 38 CT CT NNP cord-005646-xhx9pzhj 2033 39 scan scan NN cord-005646-xhx9pzhj 2033 40 , , , cord-005646-xhx9pzhj 2033 41 and and CC cord-005646-xhx9pzhj 2033 42 demographic demographic JJ cord-005646-xhx9pzhj 2033 43 characteristics characteristic NNS cord-005646-xhx9pzhj 2033 44 were be VBD cord-005646-xhx9pzhj 2033 45 analyzed analyze VBN cord-005646-xhx9pzhj 2033 46 for for IN cord-005646-xhx9pzhj 2033 47 an an DT cord-005646-xhx9pzhj 2033 48 association association NN cord-005646-xhx9pzhj 2033 49 with with IN cord-005646-xhx9pzhj 2033 50 death death NN cord-005646-xhx9pzhj 2033 51 or or CC cord-005646-xhx9pzhj 2033 52 vegetative vegetative JJ cord-005646-xhx9pzhj 2033 53 survival survival NN cord-005646-xhx9pzhj 2033 54 at at IN cord-005646-xhx9pzhj 2033 55 6 6 CD cord-005646-xhx9pzhj 2033 56 months month NNS cord-005646-xhx9pzhj 2033 57 . . . cord-005646-xhx9pzhj 2034 1 A a DT cord-005646-xhx9pzhj 2034 2 tree tree NN cord-005646-xhx9pzhj 2034 3 diagram diagram NN cord-005646-xhx9pzhj 2034 4 in in IN cord-005646-xhx9pzhj 2034 5 which which WDT cord-005646-xhx9pzhj 2034 6 risk risk NN cord-005646-xhx9pzhj 2034 7 factors factor NNS cord-005646-xhx9pzhj 2034 8 may may MD cord-005646-xhx9pzhj 2034 9 differ differ VB cord-005646-xhx9pzhj 2034 10 within within IN cord-005646-xhx9pzhj 2034 11 the the DT cord-005646-xhx9pzhj 2034 12 study study NN cord-005646-xhx9pzhj 2034 13 subpopulations subpopulation NNS cord-005646-xhx9pzhj 2034 14 was be VBD cord-005646-xhx9pzhj 2034 15 constructed construct VBN cord-005646-xhx9pzhj 2034 16 using use VBG cord-005646-xhx9pzhj 2034 17 recursive recursive JJ cord-005646-xhx9pzhj 2034 18 partitioning partitioning NN cord-005646-xhx9pzhj 2034 19 . . . cord-005646-xhx9pzhj 2035 1 Results result NNS cord-005646-xhx9pzhj 2035 2 : : : cord-005646-xhx9pzhj 2036 1 Chitdren Chitdren NNP cord-005646-xhx9pzhj 2036 2 with with IN cord-005646-xhx9pzhj 2036 3 a a DT cord-005646-xhx9pzhj 2036 4 motor motor NN cord-005646-xhx9pzhj 2036 5 score score NN cord-005646-xhx9pzhj 2036 6 _ _ NN cord-005646-xhx9pzhj 2036 7 < < XX cord-005646-xhx9pzhj 2036 8 2 2 CD cord-005646-xhx9pzhj 2036 9 had have VBD cord-005646-xhx9pzhj 2036 10 an an DT cord-005646-xhx9pzhj 2036 11 11-fold 11-fold JJ cord-005646-xhx9pzhj 2036 12 increased increase VBN cord-005646-xhx9pzhj 2036 13 risk risk NN cord-005646-xhx9pzhj 2036 14 of of IN cord-005646-xhx9pzhj 2036 15 poor poor JJ cord-005646-xhx9pzhj 2036 16 outcome outcome NN cord-005646-xhx9pzhj 2036 17 compared compare VBN cord-005646-xhx9pzhj 2036 18 to to IN cord-005646-xhx9pzhj 2036 19 those those DT cord-005646-xhx9pzhj 2036 20 with with IN cord-005646-xhx9pzhj 2036 21 motor motor NN cord-005646-xhx9pzhj 2036 22 scores score NNS cord-005646-xhx9pzhj 2036 23 > > XX cord-005646-xhx9pzhj 2036 24 2 2 CD cord-005646-xhx9pzhj 2036 25 . . . cord-005646-xhx9pzhj 2037 1 Among among IN cord-005646-xhx9pzhj 2037 2 patients patient NNS cord-005646-xhx9pzhj 2037 3 with with IN cord-005646-xhx9pzhj 2037 4 scores score NNS cord-005646-xhx9pzhj 2037 5 of of IN cord-005646-xhx9pzhj 2037 6 _ _ NN cord-005646-xhx9pzhj 2037 7 < < XX cord-005646-xhx9pzhj 2037 8 2 2 CD cord-005646-xhx9pzhj 2037 9 , , , cord-005646-xhx9pzhj 2037 10 those those DT cord-005646-xhx9pzhj 2037 11 with with IN cord-005646-xhx9pzhj 2037 12 abnormal abnormal JJ cord-005646-xhx9pzhj 2037 13 pupillary pupillary JJ cord-005646-xhx9pzhj 2037 14 reflexes reflex NNS cord-005646-xhx9pzhj 2037 15 experienced experience VBD cord-005646-xhx9pzhj 2037 16 a a DT cord-005646-xhx9pzhj 2037 17 13-fold 13-fold JJ cord-005646-xhx9pzhj 2037 18 increased increase VBN cord-005646-xhx9pzhj 2037 19 risk risk NN cord-005646-xhx9pzhj 2037 20 of of IN cord-005646-xhx9pzhj 2037 21 death death NN cord-005646-xhx9pzhj 2037 22 compared compare VBN cord-005646-xhx9pzhj 2037 23 to to IN cord-005646-xhx9pzhj 2037 24 those those DT cord-005646-xhx9pzhj 2037 25 with with IN cord-005646-xhx9pzhj 2037 26 normal normal JJ cord-005646-xhx9pzhj 2037 27 pupillary pupillary JJ cord-005646-xhx9pzhj 2037 28 reflexes reflex NNS cord-005646-xhx9pzhj 2037 29 . . . cord-005646-xhx9pzhj 2038 1 Among among IN cord-005646-xhx9pzhj 2038 2 patients patient NNS cord-005646-xhx9pzhj 2038 3 with with IN cord-005646-xhx9pzhj 2038 4 a a DT cord-005646-xhx9pzhj 2038 5 motor motor NN cord-005646-xhx9pzhj 2038 6 score score NN cord-005646-xhx9pzhj 2038 7 > > XX cord-005646-xhx9pzhj 2038 8 2 2 CD cord-005646-xhx9pzhj 2038 9 , , , cord-005646-xhx9pzhj 2038 10 an an DT cord-005646-xhx9pzhj 2038 11 intracranial intracranial JJ cord-005646-xhx9pzhj 2038 12 diagnosis diagnosis NN cord-005646-xhx9pzhj 2038 13 code code NN cord-005646-xhx9pzhj 2038 14 ( ( -LRB- cord-005646-xhx9pzhj 2038 15 no no DT cord-005646-xhx9pzhj 2038 16 pathology pathology NN cord-005646-xhx9pzhj 2038 17 , , , cord-005646-xhx9pzhj 2038 18 mild mild JJ cord-005646-xhx9pzhj 2038 19 shift shift NN cord-005646-xhx9pzhj 2038 20 _ _ NN cord-005646-xhx9pzhj 2038 21 < < XX cord-005646-xhx9pzhj 2038 22 5 5 CD cord-005646-xhx9pzhj 2038 23 mm mm NN cord-005646-xhx9pzhj 2038 24 , , , cord-005646-xhx9pzhj 2038 25 swelling swelling NN cord-005646-xhx9pzhj 2038 26 , , , cord-005646-xhx9pzhj 2038 27 shift shift VB cord-005646-xhx9pzhj 2038 28 > > XX cord-005646-xhx9pzhj 2038 29 5 5 CD cord-005646-xhx9pzhj 2038 30 mm mm NN cord-005646-xhx9pzhj 2038 31 , , , cord-005646-xhx9pzhj 2038 32 surgical surgical JJ cord-005646-xhx9pzhj 2038 33 mass mass NN cord-005646-xhx9pzhj 2038 34 lesions lesion NNS cord-005646-xhx9pzhj 2038 35 , , , cord-005646-xhx9pzhj 2038 36 or or CC cord-005646-xhx9pzhj 2038 37 non non JJ cord-005646-xhx9pzhj 2038 38 - - JJ cord-005646-xhx9pzhj 2038 39 operative operative JJ cord-005646-xhx9pzhj 2038 40 mass mass NN cord-005646-xhx9pzhj 2038 41 lesions lesion NNS cord-005646-xhx9pzhj 2038 42 ) ) -RRB- cord-005646-xhx9pzhj 2038 43 was be VBD cord-005646-xhx9pzhj 2038 44 highly highly RB cord-005646-xhx9pzhj 2038 45 predicative predicative JJ cord-005646-xhx9pzhj 2038 46 of of IN cord-005646-xhx9pzhj 2038 47 poor poor JJ cord-005646-xhx9pzhj 2038 48 outcome outcome NN cord-005646-xhx9pzhj 2038 49 at at IN cord-005646-xhx9pzhj 2038 50 6 6 CD cord-005646-xhx9pzhj 2038 51 months month NNS cord-005646-xhx9pzhj 2038 52 . . . cord-005646-xhx9pzhj 2039 1 Children child NNS cord-005646-xhx9pzhj 2039 2 with with IN cord-005646-xhx9pzhj 2039 3 CT CT NNP cord-005646-xhx9pzhj 2039 4 findings finding NNS cord-005646-xhx9pzhj 2039 5 other other JJ cord-005646-xhx9pzhj 2039 6 than than IN cord-005646-xhx9pzhj 2039 7 normal normal JJ cord-005646-xhx9pzhj 2039 8 or or CC cord-005646-xhx9pzhj 2039 9 mild mild JJ cord-005646-xhx9pzhj 2039 10 swelling swelling NN cord-005646-xhx9pzhj 2039 11 had have VBD cord-005646-xhx9pzhj 2039 12 a a DT cord-005646-xhx9pzhj 2039 13 4-fold 4-fold JJ cord-005646-xhx9pzhj 2039 14 increased increased JJ cord-005646-xhx9pzhj 2039 15 risk risk NN cord-005646-xhx9pzhj 2039 16 of of IN cord-005646-xhx9pzhj 2039 17 poor poor JJ cord-005646-xhx9pzhj 2039 18 outcome outcome NN cord-005646-xhx9pzhj 2039 19 . . . cord-005646-xhx9pzhj 2040 1 Of of IN cord-005646-xhx9pzhj 2040 2 children child NNS cord-005646-xhx9pzhj 2040 3 with with IN cord-005646-xhx9pzhj 2040 4 swelling swelling NN cord-005646-xhx9pzhj 2040 5 , , , cord-005646-xhx9pzhj 2040 6 shift shift JJ cord-005646-xhx9pzhj 2040 7 or or CC cord-005646-xhx9pzhj 2040 8 mass mass JJ cord-005646-xhx9pzhj 2040 9 lesions lesion NNS cord-005646-xhx9pzhj 2040 10 , , , cord-005646-xhx9pzhj 2040 11 the the DT cord-005646-xhx9pzhj 2040 12 pupillary pupillary JJ cord-005646-xhx9pzhj 2040 13 light light JJ cord-005646-xhx9pzhj 2040 14 reflex reflex NN cord-005646-xhx9pzhj 2040 15 was be VBD cord-005646-xhx9pzhj 2040 16 associated associate VBN cord-005646-xhx9pzhj 2040 17 with with IN cord-005646-xhx9pzhj 2040 18 outcome outcome NN cord-005646-xhx9pzhj 2040 19 . . . cord-005646-xhx9pzhj 2041 1 Children child NNS cord-005646-xhx9pzhj 2041 2 with with IN cord-005646-xhx9pzhj 2041 3 abnormal abnormal JJ cord-005646-xhx9pzhj 2041 4 pupils pupil NNS cord-005646-xhx9pzhj 2041 5 had have VBD cord-005646-xhx9pzhj 2041 6 a a DT cord-005646-xhx9pzhj 2041 7 6-fold 6-fold CD cord-005646-xhx9pzhj 2041 8 increased increase VBN cord-005646-xhx9pzhj 2041 9 risk risk NN cord-005646-xhx9pzhj 2041 10 of of IN cord-005646-xhx9pzhj 2041 11 poor poor JJ cord-005646-xhx9pzhj 2041 12 outcome outcome NN cord-005646-xhx9pzhj 2041 13 . . . cord-005646-xhx9pzhj 2042 1 Discussion discussion NN cord-005646-xhx9pzhj 2042 2 : : : cord-005646-xhx9pzhj 2043 1 A a DT cord-005646-xhx9pzhj 2043 2 few few JJ cord-005646-xhx9pzhj 2043 3 clinical clinical JJ cord-005646-xhx9pzhj 2043 4 and and CC cord-005646-xhx9pzhj 2043 5 radiographic radiographic JJ cord-005646-xhx9pzhj 2043 6 features feature NNS cord-005646-xhx9pzhj 2043 7 stratified stratified JJ cord-005646-xhx9pzhj 2043 8 comatose comatose JJ cord-005646-xhx9pzhj 2043 9 children child NNS cord-005646-xhx9pzhj 2043 10 into into IN cord-005646-xhx9pzhj 2043 11 fairly fairly RB cord-005646-xhx9pzhj 2043 12 distinct distinct JJ cord-005646-xhx9pzhj 2043 13 risk risk NN cord-005646-xhx9pzhj 2043 14 groups group NNS cord-005646-xhx9pzhj 2043 15 . . . cord-005646-xhx9pzhj 2044 1 Information information NN cord-005646-xhx9pzhj 2044 2 available available JJ cord-005646-xhx9pzhj 2044 3 early early RB cord-005646-xhx9pzhj 2044 4 after after IN cord-005646-xhx9pzhj 2044 5 traumatic traumatic JJ cord-005646-xhx9pzhj 2044 6 brain brain NN cord-005646-xhx9pzhj 2044 7 injury injury NN cord-005646-xhx9pzhj 2044 8 in in IN cord-005646-xhx9pzhj 2044 9 comatose comatose JJ cord-005646-xhx9pzhj 2044 10 children child NNS cord-005646-xhx9pzhj 2044 11 provides provide VBZ cord-005646-xhx9pzhj 2044 12 useful useful JJ cord-005646-xhx9pzhj 2044 13 prognostic prognostic JJ cord-005646-xhx9pzhj 2044 14 information information NN cord-005646-xhx9pzhj 2044 15 on on IN cord-005646-xhx9pzhj 2044 16 the the DT cord-005646-xhx9pzhj 2044 17 likelihood likelihood NN cord-005646-xhx9pzhj 2044 18 of of IN cord-005646-xhx9pzhj 2044 19 death death NN cord-005646-xhx9pzhj 2044 20 or or CC cord-005646-xhx9pzhj 2044 21 devastating devastating JJ cord-005646-xhx9pzhj 2044 22 injury injury NN cord-005646-xhx9pzhj 2044 23 . . . cord-005646-xhx9pzhj 2045 1 A a DT cord-005646-xhx9pzhj 2045 2 retrospective retrospective JJ cord-005646-xhx9pzhj 2045 3 study study NN cord-005646-xhx9pzhj 2045 4 of of IN cord-005646-xhx9pzhj 2045 5 70 70 CD cord-005646-xhx9pzhj 2045 6 children child NNS cord-005646-xhx9pzhj 2045 7 with with IN cord-005646-xhx9pzhj 2045 8 the the DT cord-005646-xhx9pzhj 2045 9 diagnosis diagnosis NN cord-005646-xhx9pzhj 2045 10 of of IN cord-005646-xhx9pzhj 2045 11 epidural epidural NN cord-005646-xhx9pzhj 2045 12 hematoma hematoma NN cord-005646-xhx9pzhj 2045 13 was be VBD cord-005646-xhx9pzhj 2045 14 made make VBN cord-005646-xhx9pzhj 2045 15 during during IN cord-005646-xhx9pzhj 2045 16 1990 1990 CD cord-005646-xhx9pzhj 2045 17 - - SYM cord-005646-xhx9pzhj 2045 18 1995 1995 CD cord-005646-xhx9pzhj 2045 19 period period NN cord-005646-xhx9pzhj 2045 20 . . . cord-005646-xhx9pzhj 2046 1 Ages age NNS cord-005646-xhx9pzhj 2046 2 ranged range VBD cord-005646-xhx9pzhj 2046 3 between between IN cord-005646-xhx9pzhj 2046 4 7 7 CD cord-005646-xhx9pzhj 2046 5 days day NNS cord-005646-xhx9pzhj 2046 6 and and CC cord-005646-xhx9pzhj 2046 7 17 17 CD cord-005646-xhx9pzhj 2046 8 years year NNS cord-005646-xhx9pzhj 2046 9 ( ( -LRB- cord-005646-xhx9pzhj 2046 10 18 18 CD cord-005646-xhx9pzhj 2046 11 % % NN cord-005646-xhx9pzhj 2046 12 less less JJR cord-005646-xhx9pzhj 2046 13 than than IN cord-005646-xhx9pzhj 2046 14 1 1 CD cord-005646-xhx9pzhj 2046 15 year year NN cord-005646-xhx9pzhj 2046 16 , , , cord-005646-xhx9pzhj 2046 17 40 40 CD cord-005646-xhx9pzhj 2046 18 % % NN cord-005646-xhx9pzhj 2046 19 between between IN cord-005646-xhx9pzhj 2046 20 1 1 CD cord-005646-xhx9pzhj 2046 21 and and CC cord-005646-xhx9pzhj 2046 22 10 10 CD cord-005646-xhx9pzhj 2046 23 years year NNS cord-005646-xhx9pzhj 2046 24 , , , cord-005646-xhx9pzhj 2046 25 and and CC cord-005646-xhx9pzhj 2046 26 42 42 CD cord-005646-xhx9pzhj 2046 27 % % NN cord-005646-xhx9pzhj 2046 28 older old JJR cord-005646-xhx9pzhj 2046 29 than than IN cord-005646-xhx9pzhj 2046 30 10 10 CD cord-005646-xhx9pzhj 2046 31 years year NNS cord-005646-xhx9pzhj 2046 32 ) ) -RRB- cord-005646-xhx9pzhj 2046 33 , , , cord-005646-xhx9pzhj 2046 34 82 82 CD cord-005646-xhx9pzhj 2046 35 % % NN cord-005646-xhx9pzhj 2046 36 of of IN cord-005646-xhx9pzhj 2046 37 them -PRON- PRP cord-005646-xhx9pzhj 2046 38 were be VBD cord-005646-xhx9pzhj 2046 39 admitted admit VBN cord-005646-xhx9pzhj 2046 40 at at IN cord-005646-xhx9pzhj 2046 41 the the DT cord-005646-xhx9pzhj 2046 42 PICU PICU NNP cord-005646-xhx9pzhj 2046 43 . . . cord-005646-xhx9pzhj 2047 1 51 51 CD cord-005646-xhx9pzhj 2047 2 % % NN cord-005646-xhx9pzhj 2047 3 of of IN cord-005646-xhx9pzhj 2047 4 the the DT cord-005646-xhx9pzhj 2047 5 cases case NNS cord-005646-xhx9pzhj 2047 6 were be VBD cord-005646-xhx9pzhj 2047 7 due due JJ cord-005646-xhx9pzhj 2047 8 to to IN cord-005646-xhx9pzhj 2047 9 falls fall NNS cord-005646-xhx9pzhj 2047 10 , , , cord-005646-xhx9pzhj 2047 11 35 35 CD cord-005646-xhx9pzhj 2047 12 % % NN cord-005646-xhx9pzhj 2047 13 to to IN cord-005646-xhx9pzhj 2047 14 road road NN cord-005646-xhx9pzhj 2047 15 traffic traffic NN cord-005646-xhx9pzhj 2047 16 accident accident NN cord-005646-xhx9pzhj 2047 17 and and CC cord-005646-xhx9pzhj 2047 18 14 14 CD cord-005646-xhx9pzhj 2047 19 % % NN cord-005646-xhx9pzhj 2047 20 to to IN cord-005646-xhx9pzhj 2047 21 other other JJ cord-005646-xhx9pzhj 2047 22 causes cause NNS cord-005646-xhx9pzhj 2047 23 . . . cord-005646-xhx9pzhj 2048 1 On on IN cord-005646-xhx9pzhj 2048 2 admission admission NN cord-005646-xhx9pzhj 2048 3 GCS GCS NNP cord-005646-xhx9pzhj 2048 4 was be VBD cord-005646-xhx9pzhj 2048 5 less less JJR cord-005646-xhx9pzhj 2048 6 than than IN cord-005646-xhx9pzhj 2048 7 8 8 CD cord-005646-xhx9pzhj 2048 8 in in IN cord-005646-xhx9pzhj 2048 9 19 19 CD cord-005646-xhx9pzhj 2048 10 % % NN cord-005646-xhx9pzhj 2048 11 of of IN cord-005646-xhx9pzhj 2048 12 the the DT cord-005646-xhx9pzhj 2048 13 cases case NNS cord-005646-xhx9pzhj 2048 14 and and CC cord-005646-xhx9pzhj 2048 15 more more JJR cord-005646-xhx9pzhj 2048 16 than than IN cord-005646-xhx9pzhj 2048 17 14 14 CD cord-005646-xhx9pzhj 2048 18 in in IN cord-005646-xhx9pzhj 2048 19 53 53 CD cord-005646-xhx9pzhj 2048 20 % % NN cord-005646-xhx9pzhj 2048 21 . . . cord-005646-xhx9pzhj 2049 1 Diagnosis diagnosis NN cord-005646-xhx9pzhj 2049 2 was be VBD cord-005646-xhx9pzhj 2049 3 made make VBN cord-005646-xhx9pzhj 2049 4 during during IN cord-005646-xhx9pzhj 2049 5 first first JJ cord-005646-xhx9pzhj 2049 6 4 4 CD cord-005646-xhx9pzhj 2049 7 hours hour NNS cord-005646-xhx9pzhj 2049 8 in in IN cord-005646-xhx9pzhj 2049 9 63 63 CD cord-005646-xhx9pzhj 2049 10 % % NN cord-005646-xhx9pzhj 2049 11 of of IN cord-005646-xhx9pzhj 2049 12 patients patient NNS cord-005646-xhx9pzhj 2049 13 and and CC cord-005646-xhx9pzhj 2049 14 delayed delay VBN cord-005646-xhx9pzhj 2049 15 more more JJR cord-005646-xhx9pzhj 2049 16 than than IN cord-005646-xhx9pzhj 2049 17 12 12 CD cord-005646-xhx9pzhj 2049 18 hours hour NNS cord-005646-xhx9pzhj 2049 19 in in IN cord-005646-xhx9pzhj 2049 20 28 28 CD cord-005646-xhx9pzhj 2049 21 % % NN cord-005646-xhx9pzhj 2049 22 of of IN cord-005646-xhx9pzhj 2049 23 them -PRON- PRP cord-005646-xhx9pzhj 2049 24 . . . cord-005646-xhx9pzhj 2050 1 Neurologic neurologic JJ cord-005646-xhx9pzhj 2050 2 impairment impairment NN cord-005646-xhx9pzhj 2050 3 was be VBD cord-005646-xhx9pzhj 2050 4 present present JJ cord-005646-xhx9pzhj 2050 5 at at IN cord-005646-xhx9pzhj 2050 6 admission admission NN cord-005646-xhx9pzhj 2050 7 in in IN cord-005646-xhx9pzhj 2050 8 33 33 CD cord-005646-xhx9pzhj 2050 9 % % NN cord-005646-xhx9pzhj 2050 10 of of IN cord-005646-xhx9pzhj 2050 11 patients patient NNS cord-005646-xhx9pzhj 2050 12 , , , cord-005646-xhx9pzhj 2050 13 and and CC cord-005646-xhx9pzhj 2050 14 delayed delay VBN cord-005646-xhx9pzhj 2050 15 in in IN cord-005646-xhx9pzhj 2050 16 30 30 CD cord-005646-xhx9pzhj 2050 17 % % NN cord-005646-xhx9pzhj 2050 18 . . . cord-005646-xhx9pzhj 2051 1 Even even RB cord-005646-xhx9pzhj 2051 2 so,27 so,27 CD cord-005646-xhx9pzhj 2051 3 % % NN cord-005646-xhx9pzhj 2051 4 remained remain VBD cord-005646-xhx9pzhj 2051 5 without without IN cord-005646-xhx9pzhj 2051 6 impairment impairment NN cord-005646-xhx9pzhj 2051 7 . . . cord-005646-xhx9pzhj 2052 1 Radiological radiological JJ cord-005646-xhx9pzhj 2052 2 findings finding NNS cord-005646-xhx9pzhj 2052 3 at at IN cord-005646-xhx9pzhj 2052 4 first first JJ cord-005646-xhx9pzhj 2052 5 CT CT NNP cord-005646-xhx9pzhj 2052 6 were be VBD cord-005646-xhx9pzhj 2052 7 skull skull NN cord-005646-xhx9pzhj 2052 8 fracture fracture NN cord-005646-xhx9pzhj 2052 9 ( ( -LRB- cord-005646-xhx9pzhj 2052 10 68 68 CD cord-005646-xhx9pzhj 2052 11 % % NN cord-005646-xhx9pzhj 2052 12 ) ) -RRB- cord-005646-xhx9pzhj 2052 13 ; ; , cord-005646-xhx9pzhj 2052 14 epidural epidural NNP cord-005646-xhx9pzhj 2052 15 hematoma hematoma NN cord-005646-xhx9pzhj 2052 16 localization localization NN cord-005646-xhx9pzhj 2052 17 was be VBD cord-005646-xhx9pzhj 2052 18 : : : cord-005646-xhx9pzhj 2052 19 in in IN cord-005646-xhx9pzhj 2052 20 the the DT cord-005646-xhx9pzhj 2052 21 right right JJ cord-005646-xhx9pzhj 2052 22 side side NN cord-005646-xhx9pzhj 2052 23 ( ( -LRB- cord-005646-xhx9pzhj 2052 24 63 63 CD cord-005646-xhx9pzhj 2052 25 % % NN cord-005646-xhx9pzhj 2052 26 ) ) -RRB- cord-005646-xhx9pzhj 2052 27 , , , cord-005646-xhx9pzhj 2052 28 frontal frontal JJ cord-005646-xhx9pzhj 2052 29 area area NN cord-005646-xhx9pzhj 2052 30 ( ( -LRB- cord-005646-xhx9pzhj 2052 31 24 24 CD cord-005646-xhx9pzhj 2052 32 % % NN cord-005646-xhx9pzhj 2052 33 ) ) -RRB- cord-005646-xhx9pzhj 2052 34 , , , cord-005646-xhx9pzhj 2052 35 temporoparietal temporoparietal NNP cord-005646-xhx9pzhj 2052 36 ( ( -LRB- cord-005646-xhx9pzhj 2052 37 66 66 CD cord-005646-xhx9pzhj 2052 38 % % NN cord-005646-xhx9pzhj 2052 39 ) ) -RRB- cord-005646-xhx9pzhj 2052 40 and and CC cord-005646-xhx9pzhj 2052 41 occipital occipital JJ cord-005646-xhx9pzhj 2052 42 ( ( -LRB- cord-005646-xhx9pzhj 2052 43 t0 t0 NNP cord-005646-xhx9pzhj 2052 44 % % NN cord-005646-xhx9pzhj 2052 45 ) ) -RRB- cord-005646-xhx9pzhj 2052 46 . . . cord-005646-xhx9pzhj 2053 1 Associated associated JJ cord-005646-xhx9pzhj 2053 2 lesions lesion NNS cord-005646-xhx9pzhj 2053 3 were be VBD cord-005646-xhx9pzhj 2053 4 : : : cord-005646-xhx9pzhj 2053 5 several several JJ cord-005646-xhx9pzhj 2053 6 ( ( -LRB- cord-005646-xhx9pzhj 2053 7 13 13 CD cord-005646-xhx9pzhj 2053 8 % % NN cord-005646-xhx9pzhj 2053 9 ) ) -RRB- cord-005646-xhx9pzhj 2053 10 or or CC cord-005646-xhx9pzhj 2053 11 unilateral unilateral JJ cord-005646-xhx9pzhj 2053 12 ( ( -LRB- cord-005646-xhx9pzhj 2053 13 51 51 CD cord-005646-xhx9pzhj 2053 14 % % NN cord-005646-xhx9pzhj 2053 15 ) ) -RRB- cord-005646-xhx9pzhj 2053 16 cerebral cerebral JJ cord-005646-xhx9pzhj 2053 17 contusions contusion NNS cord-005646-xhx9pzhj 2053 18 , , , cord-005646-xhx9pzhj 2053 19 diffuse diffuse VB cord-005646-xhx9pzhj 2053 20 brain brain NN cord-005646-xhx9pzhj 2053 21 oedema oedema NN cord-005646-xhx9pzhj 2053 22 ( ( -LRB- cord-005646-xhx9pzhj 2053 23 10 10 CD cord-005646-xhx9pzhj 2053 24 % % NN cord-005646-xhx9pzhj 2053 25 ) ) -RRB- cord-005646-xhx9pzhj 2053 26 , , , cord-005646-xhx9pzhj 2053 27 unilateral unilateral JJ cord-005646-xhx9pzhj 2053 28 hemispheric hemispheric JJ cord-005646-xhx9pzhj 2053 29 oedema oedema NN cord-005646-xhx9pzhj 2053 30 ( ( -LRB- cord-005646-xhx9pzhj 2053 31 14 14 CD cord-005646-xhx9pzhj 2053 32 % % NN cord-005646-xhx9pzhj 2053 33 ) ) -RRB- cord-005646-xhx9pzhj 2053 34 and and CC cord-005646-xhx9pzhj 2053 35 38 38 CD cord-005646-xhx9pzhj 2053 36 % % NN cord-005646-xhx9pzhj 2053 37 showed show VBD cord-005646-xhx9pzhj 2053 38 shifted shift VBN cord-005646-xhx9pzhj 2053 39 middle middle JJ cord-005646-xhx9pzhj 2053 40 line line NN cord-005646-xhx9pzhj 2053 41 . . . cord-005646-xhx9pzhj 2054 1 Four four CD cord-005646-xhx9pzhj 2054 2 patients patient NNS cord-005646-xhx9pzhj 2054 3 died die VBD cord-005646-xhx9pzhj 2054 4 , , , cord-005646-xhx9pzhj 2054 5 half half NN cord-005646-xhx9pzhj 2054 6 of of IN cord-005646-xhx9pzhj 2054 7 them -PRON- PRP cord-005646-xhx9pzhj 2054 8 during during IN cord-005646-xhx9pzhj 2054 9 the the DT cord-005646-xhx9pzhj 2054 10 first first JJ cord-005646-xhx9pzhj 2054 11 24 24 CD cord-005646-xhx9pzhj 2054 12 hours hour NNS cord-005646-xhx9pzhj 2054 13 . . . cord-005646-xhx9pzhj 2055 1 41 41 CD cord-005646-xhx9pzhj 2055 2 fully fully RB cord-005646-xhx9pzhj 2055 3 recovered recover VBD cord-005646-xhx9pzhj 2055 4 ( ( -LRB- cord-005646-xhx9pzhj 2055 5 58.6 58.6 CD cord-005646-xhx9pzhj 2055 6 % % NN cord-005646-xhx9pzhj 2055 7 ) ) -RRB- cord-005646-xhx9pzhj 2055 8 and and CC cord-005646-xhx9pzhj 2055 9 25 25 CD cord-005646-xhx9pzhj 2055 10 have have VBP cord-005646-xhx9pzhj 2055 11 sequelae sequela NNS cord-005646-xhx9pzhj 2055 12 of of IN cord-005646-xhx9pzhj 2055 13 different different JJ cord-005646-xhx9pzhj 2055 14 nature nature NN cord-005646-xhx9pzhj 2055 15 : : : cord-005646-xhx9pzhj 2055 16 7 7 CD cord-005646-xhx9pzhj 2055 17 were be VBD cord-005646-xhx9pzhj 2055 18 left leave VBN cord-005646-xhx9pzhj 2055 19 with with IN cord-005646-xhx9pzhj 2055 20 severe severe JJ cord-005646-xhx9pzhj 2055 21 motor motor NN cord-005646-xhx9pzhj 2055 22 disability disability NN cord-005646-xhx9pzhj 2055 23 ( ( -LRB- cord-005646-xhx9pzhj 2055 24 10 10 CD cord-005646-xhx9pzhj 2055 25 % % NN cord-005646-xhx9pzhj 2055 26 ) ) -RRB- cord-005646-xhx9pzhj 2055 27 ; ; : cord-005646-xhx9pzhj 2055 28 at at IN cord-005646-xhx9pzhj 2055 29 the the DT cord-005646-xhx9pzhj 2055 30 follow follow NN cord-005646-xhx9pzhj 2055 31 - - HYPH cord-005646-xhx9pzhj 2055 32 up up NN cord-005646-xhx9pzhj 2055 33 t3 t3 NNP cord-005646-xhx9pzhj 2055 34 have have VBP cord-005646-xhx9pzhj 2055 35 some some DT cord-005646-xhx9pzhj 2055 36 degree degree NN cord-005646-xhx9pzhj 2055 37 of of IN cord-005646-xhx9pzhj 2055 38 neurodisability neurodisability NN cord-005646-xhx9pzhj 2055 39 . . . cord-005646-xhx9pzhj 2056 1 Next next JJ cord-005646-xhx9pzhj 2056 2 datas data NNS cord-005646-xhx9pzhj 2056 3 keep keep VBP cord-005646-xhx9pzhj 2056 4 correlation correlation NN cord-005646-xhx9pzhj 2056 5 with with IN cord-005646-xhx9pzhj 2056 6 death death NN cord-005646-xhx9pzhj 2056 7 or or CC cord-005646-xhx9pzhj 2056 8 neurosurgical neurosurgical JJ cord-005646-xhx9pzhj 2056 9 impairment impairment NN cord-005646-xhx9pzhj 2056 10 : : : cord-005646-xhx9pzhj 2056 11 only only RB cord-005646-xhx9pzhj 2056 12 were be VBD cord-005646-xhx9pzhj 2056 13 significative significative JJ cord-005646-xhx9pzhj 2056 14 multiple multiple JJ cord-005646-xhx9pzhj 2056 15 cerebral cerebral JJ cord-005646-xhx9pzhj 2056 16 contusion contusion NN cord-005646-xhx9pzhj 2056 17 ( ( -LRB- cord-005646-xhx9pzhj 2056 18 p=0.002 p=0.002 NNP cord-005646-xhx9pzhj 2056 19 ) ) -RRB- cord-005646-xhx9pzhj 2056 20 and and CC cord-005646-xhx9pzhj 2056 21 brain brain NN cord-005646-xhx9pzhj 2056 22 oedema oedema NN cord-005646-xhx9pzhj 2056 23 ( ( -LRB- cord-005646-xhx9pzhj 2056 24 p=0.05 p=0.05 NNP cord-005646-xhx9pzhj 2056 25 ) ) -RRB- cord-005646-xhx9pzhj 2056 26 , , , cord-005646-xhx9pzhj 2056 27 GCS GCS NNP cord-005646-xhx9pzhj 2057 1 less less JJR cord-005646-xhx9pzhj 2057 2 than than IN cord-005646-xhx9pzhj 2057 3 8 8 CD cord-005646-xhx9pzhj 2057 4 at at IN cord-005646-xhx9pzhj 2057 5 the the DT cord-005646-xhx9pzhj 2057 6 admission admission NN cord-005646-xhx9pzhj 2057 7 ( ( -LRB- cord-005646-xhx9pzhj 2057 8 p--0.002 p--0.002 ADD cord-005646-xhx9pzhj 2057 9 ) ) -RRB- cord-005646-xhx9pzhj 2057 10 , , , cord-005646-xhx9pzhj 2057 11 shock shock NN cord-005646-xhx9pzhj 2057 12 ( ( -LRB- cord-005646-xhx9pzhj 2057 13 p=0.003 p=0.003 NNP cord-005646-xhx9pzhj 2057 14 ) ) -RRB- cord-005646-xhx9pzhj 2057 15 and and CC cord-005646-xhx9pzhj 2057 16 remaining remain VBG cord-005646-xhx9pzhj 2057 17 cerebral cerebral JJ cord-005646-xhx9pzhj 2057 18 contusion contusion NN cord-005646-xhx9pzhj 2057 19 in in IN cord-005646-xhx9pzhj 2057 20 control control NN cord-005646-xhx9pzhj 2057 21 CT CT NNP cord-005646-xhx9pzhj 2057 22 correlated correlate VBD cord-005646-xhx9pzhj 2057 23 with with IN cord-005646-xhx9pzhj 2057 24 death death NN cord-005646-xhx9pzhj 2057 25 or or CC cord-005646-xhx9pzhj 2057 26 diasability diasability NN cord-005646-xhx9pzhj 2057 27 at at IN cord-005646-xhx9pzhj 2057 28 discharge discharge NN cord-005646-xhx9pzhj 2057 29 . . . cord-005646-xhx9pzhj 2058 1 On on IN cord-005646-xhx9pzhj 2058 2 the the DT cord-005646-xhx9pzhj 2058 3 other other JJ cord-005646-xhx9pzhj 2058 4 hand hand NN cord-005646-xhx9pzhj 2058 5 , , , cord-005646-xhx9pzhj 2058 6 neither neither CC cord-005646-xhx9pzhj 2058 7 surgical surgical JJ cord-005646-xhx9pzhj 2058 8 drainage drainage NN cord-005646-xhx9pzhj 2058 9 volume volume NN cord-005646-xhx9pzhj 2058 10 nor nor CC cord-005646-xhx9pzhj 2058 11 first first JJ cord-005646-xhx9pzhj 2058 12 or or CC cord-005646-xhx9pzhj 2058 13 highest high JJS cord-005646-xhx9pzhj 2058 14 levels level NNS cord-005646-xhx9pzhj 2058 15 of of IN cord-005646-xhx9pzhj 2058 16 ICP ICP NNP cord-005646-xhx9pzhj 2058 17 ( ( -LRB- cord-005646-xhx9pzhj 2058 18 12 12 CD cord-005646-xhx9pzhj 2058 19 cases),nor cases),nor NN cord-005646-xhx9pzhj 2058 20 pupillary pupillary JJ cord-005646-xhx9pzhj 2058 21 abnormalities abnormality NNS cord-005646-xhx9pzhj 2058 22 ( ( -LRB- cord-005646-xhx9pzhj 2058 23 10 10 CD cord-005646-xhx9pzhj 2058 24 cases case NNS cord-005646-xhx9pzhj 2058 25 ) ) -RRB- cord-005646-xhx9pzhj 2058 26 correlated correlate VBD cord-005646-xhx9pzhj 2058 27 with with IN cord-005646-xhx9pzhj 2058 28 worse bad JJR cord-005646-xhx9pzhj 2058 29 prognosis prognosis NN cord-005646-xhx9pzhj 2058 30 . . . cord-005646-xhx9pzhj 2059 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2059 2 : : : cord-005646-xhx9pzhj 2060 1 GCS GCS NNP cord-005646-xhx9pzhj 2060 2 equal equal JJ cord-005646-xhx9pzhj 2060 3 or or CC cord-005646-xhx9pzhj 2060 4 less less JJR cord-005646-xhx9pzhj 2060 5 than than IN cord-005646-xhx9pzhj 2060 6 8 8 CD cord-005646-xhx9pzhj 2060 7 an an DT cord-005646-xhx9pzhj 2060 8 shock shock NN cord-005646-xhx9pzhj 2060 9 are be VBP cord-005646-xhx9pzhj 2060 10 main main JJ cord-005646-xhx9pzhj 2060 11 factors factor NNS cord-005646-xhx9pzhj 2060 12 related relate VBN cord-005646-xhx9pzhj 2060 13 to to IN cord-005646-xhx9pzhj 2060 14 worse bad JJR cord-005646-xhx9pzhj 2060 15 prognosis prognosis NN cord-005646-xhx9pzhj 2060 16 , , , cord-005646-xhx9pzhj 2060 17 also also RB cord-005646-xhx9pzhj 2060 18 multiple multiple JJ cord-005646-xhx9pzhj 2060 19 cerebral cerebral JJ cord-005646-xhx9pzhj 2060 20 contusions contusion NNS cord-005646-xhx9pzhj 2060 21 in in IN cord-005646-xhx9pzhj 2060 22 CT CT NNP cord-005646-xhx9pzhj 2060 23 and and CC cord-005646-xhx9pzhj 2060 24 diffuse diffuse VB cord-005646-xhx9pzhj 2060 25 brain brain NN cord-005646-xhx9pzhj 2060 26 oedema oedema NN cord-005646-xhx9pzhj 2060 27 . . . cord-005646-xhx9pzhj 2061 1 The the DT cord-005646-xhx9pzhj 2061 2 results result NNS cord-005646-xhx9pzhj 2061 3 of of IN cord-005646-xhx9pzhj 2061 4 a a DT cord-005646-xhx9pzhj 2061 5 modified modify VBN cord-005646-xhx9pzhj 2061 6 GCS GCS NNP cord-005646-xhx9pzhj 2061 7 were be VBD cord-005646-xhx9pzhj 2061 8 compared compare VBN cord-005646-xhx9pzhj 2061 9 to to TO cord-005646-xhx9pzhj 2061 10 outcome outcome VB cord-005646-xhx9pzhj 2061 11 and and CC cord-005646-xhx9pzhj 2061 12 intensive intensive JJ cord-005646-xhx9pzhj 2061 13 therapy therapy NN cord-005646-xhx9pzhj 2061 14 in in IN cord-005646-xhx9pzhj 2061 15 78 78 CD cord-005646-xhx9pzhj 2061 16 children child NNS cord-005646-xhx9pzhj 2061 17 ( ( -LRB- cord-005646-xhx9pzhj 2061 18 mean mean VB cord-005646-xhx9pzhj 2061 19 age age NN cord-005646-xhx9pzhj 2061 20 8,5t4,7 8,5t4,7 CD cord-005646-xhx9pzhj 2061 21 years year NNS cord-005646-xhx9pzhj 2061 22 ) ) -RRB- cord-005646-xhx9pzhj 2061 23 with with IN cord-005646-xhx9pzhj 2061 24 head head NN cord-005646-xhx9pzhj 2061 25 and and CC cord-005646-xhx9pzhj 2061 26 associated associated JJ cord-005646-xhx9pzhj 2061 27 injuries injury NNS cord-005646-xhx9pzhj 2061 28 ( ( -LRB- cord-005646-xhx9pzhj 2061 29 53,6 53,6 CD cord-005646-xhx9pzhj 2061 30 % % NN cord-005646-xhx9pzhj 2061 31 of of IN cord-005646-xhx9pzhj 2061 32 all all DT cord-005646-xhx9pzhj 2061 33 cases case NNS cord-005646-xhx9pzhj 2061 34 ) ) -RRB- cord-005646-xhx9pzhj 2061 35 of of IN cord-005646-xhx9pzhj 2061 36 different different JJ cord-005646-xhx9pzhj 2061 37 causes cause NNS cord-005646-xhx9pzhj 2061 38 ( ( -LRB- cord-005646-xhx9pzhj 2061 39 traffic traffic NN cord-005646-xhx9pzhj 2061 40 accidents accident NNS cord-005646-xhx9pzhj 2061 41 , , , cord-005646-xhx9pzhj 2061 42 falls fall VBZ cord-005646-xhx9pzhj 2061 43 ) ) -RRB- cord-005646-xhx9pzhj 2061 44 . . . cord-005646-xhx9pzhj 2062 1 The the DT cord-005646-xhx9pzhj 2062 2 GCS GCS NNP cord-005646-xhx9pzhj 2062 3 was be VBD cord-005646-xhx9pzhj 2062 4 regularly regularly RB cord-005646-xhx9pzhj 2062 5 used use VBN cord-005646-xhx9pzhj 2062 6 inn inn NNP cord-005646-xhx9pzhj 2062 7 the the DT cord-005646-xhx9pzhj 2062 8 course course NN cord-005646-xhx9pzhj 2062 9 of of IN cord-005646-xhx9pzhj 2062 10 intensive intensive JJ cord-005646-xhx9pzhj 2062 11 therapy therapy NN cord-005646-xhx9pzhj 2062 12 . . . cord-005646-xhx9pzhj 2063 1 According accord VBG cord-005646-xhx9pzhj 2063 2 to to IN cord-005646-xhx9pzhj 2063 3 our -PRON- PRP$ cord-005646-xhx9pzhj 2063 4 own own JJ cord-005646-xhx9pzhj 2063 5 and and CC cord-005646-xhx9pzhj 2063 6 other other JJ cord-005646-xhx9pzhj 2063 7 experiences experience NNS cord-005646-xhx9pzhj 2063 8 the the DT cord-005646-xhx9pzhj 2063 9 GCS GCS NNP cord-005646-xhx9pzhj 2063 10 was be VBD cord-005646-xhx9pzhj 2063 11 divided divide VBN cord-005646-xhx9pzhj 2063 12 in in IN cord-005646-xhx9pzhj 2063 13 3 3 CD cord-005646-xhx9pzhj 2063 14 stages stage NNS cord-005646-xhx9pzhj 2063 15 : : : cord-005646-xhx9pzhj 2063 16 stage stage NN cord-005646-xhx9pzhj 2063 17 1 1 CD cord-005646-xhx9pzhj 2063 18 ( ( -LRB- cord-005646-xhx9pzhj 2063 19 4 4 CD cord-005646-xhx9pzhj 2063 20 - - SYM cord-005646-xhx9pzhj 2063 21 8 8 CD cord-005646-xhx9pzhj 2063 22 points point NNS cord-005646-xhx9pzhj 2063 23 ) ) -RRB- cord-005646-xhx9pzhj 2063 24 , , , cord-005646-xhx9pzhj 2063 25 stage stage NN cord-005646-xhx9pzhj 2063 26 2 2 CD cord-005646-xhx9pzhj 2063 27 ( ( -LRB- cord-005646-xhx9pzhj 2063 28 9 9 CD cord-005646-xhx9pzhj 2063 29 - - SYM cord-005646-xhx9pzhj 2063 30 12 12 CD cord-005646-xhx9pzhj 2063 31 points point NNS cord-005646-xhx9pzhj 2063 32 ) ) -RRB- cord-005646-xhx9pzhj 2063 33 und und CC cord-005646-xhx9pzhj 2063 34 stage stage NN cord-005646-xhx9pzhj 2063 35 3 3 CD cord-005646-xhx9pzhj 2063 36 ( ( -LRB- cord-005646-xhx9pzhj 2063 37 13 13 CD cord-005646-xhx9pzhj 2063 38 - - SYM cord-005646-xhx9pzhj 2063 39 19 19 CD cord-005646-xhx9pzhj 2063 40 points point NNS cord-005646-xhx9pzhj 2063 41 ) ) -RRB- cord-005646-xhx9pzhj 2063 42 palhuiugy palhuiugy NNP cord-005646-xhx9pzhj 2063 43 wile wile NNP cord-005646-xhx9pzhj 2063 44 sP sP NNP cord-005646-xhx9pzhj 2063 45 , , , cord-005646-xhx9pzhj 2063 46 tdhlg tdhlg NNP cord-005646-xhx9pzhj 2063 47 c~'lcb1al c~'lcb1al NN cord-005646-xhx9pzhj 2063 48 blood blood NN cord-005646-xhx9pzhj 2063 49 ~0w ~0w NFP cord-005646-xhx9pzhj 2063 50 . . . cord-005646-xhx9pzhj 2064 1 Sabgcqucntl Sabgcqucntl NNP cord-005646-xhx9pzhj 2064 2 } } -RRB- cord-005646-xhx9pzhj 2064 3 . . . cord-005646-xhx9pzhj 2065 1 rhc rhc NNP cord-005646-xhx9pzhj 2065 2 slat slat NNP cord-005646-xhx9pzhj 2065 3 , , , cord-005646-xhx9pzhj 2065 4 : : : cord-005646-xhx9pzhj 2065 5 reRltncd reRltncd NNP cord-005646-xhx9pzhj 2065 6 to to IN cord-005646-xhx9pzhj 2065 7 t1011tl,91 t1011tl,91 NNP cord-005646-xhx9pzhj 2065 8 Iiltlils Iiltlils NNP cord-005646-xhx9pzhj 2065 9 . . . cord-005646-xhx9pzhj 2066 1 the the DT cord-005646-xhx9pzhj 2066 2 p0st,~pem p0st,~pem NNP cord-005646-xhx9pzhj 2066 3 ~ ~ CD cord-005646-xhx9pzhj 2066 4 v~ v~ . cord-005646-xhx9pzhj 2066 5 b}i b}i NNS cord-005646-xhx9pzhj 2066 6 ~ ~ NFP cord-005646-xhx9pzhj 2066 7 g g NNP cord-005646-xhx9pzhj 2066 8 wiJ!!,:q1 wiJ!!,:q1 NNP cord-005646-xhx9pzhj 2066 9 ! ! , cord-005646-xhx9pzhj 2066 10 , , , cord-005646-xhx9pzhj 2066 11 : : : cord-005646-xhx9pzhj 2067 1 _ _ NNP cord-005646-xhx9pzhj 2067 2 a!~p!ica!J0n~ a!~p!ica!J0n~ NNP cord-005646-xhx9pzhj 2067 3 : : : cord-005646-xhx9pzhj 2067 4 . . . cord-005646-xhx9pzhj 2068 1 4 4 CD cord-005646-xhx9pzhj 2068 2 ri~;¢ ri~;¢ NN cord-005646-xhx9pzhj 2069 1 ill ill JJ cord-005646-xhx9pzhj 2070 1 the the DT cord-005646-xhx9pzhj 2070 2 level level NN cord-005646-xhx9pzhj 2070 3 of of IN cord-005646-xhx9pzhj 2070 4 sensibflizatJou sensibflizatJou NNP cord-005646-xhx9pzhj 2070 5 lo lo NNP cord-005646-xhx9pzhj 2070 6 tile tile NNP cord-005646-xhx9pzhj 2070 7 cerebn~ cerebn~ NNP cord-005646-xhx9pzhj 2071 1 anhgrns anhgrns NNP cord-005646-xhx9pzhj 2071 2 up up IN cord-005646-xhx9pzhj 2071 3 to to IN cord-005646-xhx9pzhj 2071 4 1t.4-o7 1t.4-o7 CD cord-005646-xhx9pzhj 2072 1 was be VBD cord-005646-xhx9pzhj 2072 2 flofcd flofcd NNS cord-005646-xhx9pzhj 2073 1 iu iu IN cord-005646-xhx9pzhj 2073 2 9 9 CD cord-005646-xhx9pzhj 2074 1 I -PRON- PRP cord-005646-xhx9pzhj 2074 2 , , , cord-005646-xhx9pzhj 2074 3 alicnts alicnt NNS cord-005646-xhx9pzhj 2074 4 . . . cord-005646-xhx9pzhj 2075 1 There there RB cord-005646-xhx9pzhj 2075 2 wa.~ wa.~ NNP cord-005646-xhx9pzhj 2075 3 al~ al~ NNP cord-005646-xhx9pzhj 2075 4 iuclt iuclt NNP cord-005646-xhx9pzhj 2075 5 ~ ~ NFP cord-005646-xhx9pzhj 2075 6 a a LS cord-005646-xhx9pzhj 2075 7 ~ ~ NFP cord-005646-xhx9pzhj 2075 8 e e NFP cord-005646-xhx9pzhj 2075 9 ill ill NNP cord-005646-xhx9pzhj 2075 10 cerebral cerebral JJ cord-005646-xhx9pzhj 2075 11 vdociiJ vdociiJ NNP cord-005646-xhx9pzhj 2075 12 , , , cord-005646-xhx9pzhj 2075 13 . . . cord-005646-xhx9pzhj 2076 1 ~m ~m JJ cord-005646-xhx9pzhj 2077 1 d~;'ati0a d~;'ati0a NNP cord-005646-xhx9pzhj 2077 2 il~ il~ NN cord-005646-xhx9pzhj 2077 3 p¢fiphc p¢fiphc XX cord-005646-xhx9pzhj 2078 1 ~ai ~ai NNP cord-005646-xhx9pzhj 2078 2 re re IN cord-005646-xhx9pzhj 2078 3 ~ ~ NNP cord-005646-xhx9pzhj 2078 4 ista ista NNP cord-005646-xhx9pzhj 2078 5 / / SYM cord-005646-xhx9pzhj 2078 6 isc isc NNP cord-005646-xhx9pzhj 2078 7 of of IN cord-005646-xhx9pzhj 2078 8 the the DT cord-005646-xhx9pzhj 2078 9 large large JJ cord-005646-xhx9pzhj 2078 10 ce~'bral ce~'bral CD cord-005646-xhx9pzhj 2078 11 ve ve NN cord-005646-xhx9pzhj 2078 12 ~ ~ CD cord-005646-xhx9pzhj 2078 13 ds ds NNP cord-005646-xhx9pzhj 2078 14 . . . cord-005646-xhx9pzhj 2079 1 Neur0h;~c neur0h;~c JJ cord-005646-xhx9pzhj 2080 1 ~:yn'.pt ~:yn'.pt NNP cord-005646-xhx9pzhj 2080 2 , , , cord-005646-xhx9pzhj 2080 3 m m NNP cord-005646-xhx9pzhj 2080 4 ~ ~ NNP cord-005646-xhx9pzhj 2080 5 at0!a~ at0!a~ NNP cord-005646-xhx9pzhj 2080 6 , , , cord-005646-xhx9pzhj 2080 7 ( ( -LRB- cord-005646-xhx9pzhj 2080 8 s::mno!en~ s::mno!en~ NNP cord-005646-xhx9pzhj 2080 9 ' ' '' cord-005646-xhx9pzhj 2080 10 , , , cord-005646-xhx9pzhj 2080 11 _ _ NNP cord-005646-xhx9pzhj 2080 12 r_uscu!~r r_uscu!~r CD cord-005646-xhx9pzhj 2080 13 l~:pot0ni l~:pot0ni NNP cord-005646-xhx9pzhj 2080 14 & & CC cord-005646-xhx9pzhj 2080 15 ! ! . cord-005646-xhx9pzhj 2081 1 ryper*'flema ryper*'flema NNP cord-005646-xhx9pzhj 2081 2 ) ) -RRB- cord-005646-xhx9pzhj 2081 3 was be VBD cord-005646-xhx9pzhj 2081 4 nbserwed nbserwed NNP cord-005646-xhx9pzhj 2081 5 tu tu NNP cord-005646-xhx9pzhj 2081 6 lt lt NNP cord-005646-xhx9pzhj 2081 7 ~ ~ NNP cord-005646-xhx9pzhj 2081 8 ese ese NNP cord-005646-xhx9pzhj 2081 9 pal pal NN cord-005646-xhx9pzhj 2081 10 ~ ~ NFP cord-005646-xhx9pzhj 2081 11 enls enls NNP cord-005646-xhx9pzhj 2081 12 o. o. NNP cord-005646-xhx9pzhj 2081 13 cbruc cbruc NNP cord-005646-xhx9pzhj 2082 1 ~l ~l NNP cord-005646-xhx9pzhj 2082 2 ~0nnds ~0nnds NNP cord-005646-xhx9pzhj 2082 3 . . . cord-005646-xhx9pzhj 2083 1 rile rile VB cord-005646-xhx9pzhj 2083 2 ple ple NNP cord-005646-xhx9pzhj 2083 3 ~ ~ NFP cord-005646-xhx9pzhj 2083 4 c.ut c.ut NNP cord-005646-xhx9pzhj 2083 5 abse abse NNP cord-005646-xhx9pzhj 2084 1 ~vafion~ ~vafion~ NFP cord-005646-xhx9pzhj 2084 2 suggesl suggesl NNP cord-005646-xhx9pzhj 2084 3 ihal ihal NNP cord-005646-xhx9pzhj 2084 4 die die VBP cord-005646-xhx9pzhj 2085 1 ~tttdy ~tttdy XX cord-005646-xhx9pzhj 2085 2 at at IN cord-005646-xhx9pzhj 2085 3 " " `` cord-005646-xhx9pzhj 2085 4 Ihe Ihe NNP cord-005646-xhx9pzhj 2085 5 stale stale JJ cord-005646-xhx9pzhj 2085 6 ~f ~f NNP cord-005646-xhx9pzhj 2085 7 hematocr hematocr NNP cord-005646-xhx9pzhj 2085 8 ~ ~ NFP cord-005646-xhx9pzhj 2085 9 chcplm chcplm NNP cord-005646-xhx9pzhj 2085 10 / / SYM cord-005646-xhx9pzhj 2085 11 itic itic JJ cord-005646-xhx9pzhj 2085 12 bm bm NNP cord-005646-xhx9pzhj 2085 13 ~ ~ NNP cord-005646-xhx9pzhj 2085 14 ic~ ic~ NN cord-005646-xhx9pzhj 2085 15 in in IN cord-005646-xhx9pzhj 2085 16 ckil&en ckil&en NNP cord-005646-xhx9pzhj 2085 17 with with IN cord-005646-xhx9pzhj 2085 18 31110oN 31110on CD cord-005646-xhx9pzhj 2085 19 emergensy emergensy NN cord-005646-xhx9pzhj 2085 20 is be VBZ cord-005646-xhx9pzhj 2085 21 of of IN cord-005646-xhx9pzhj 2085 22 abviou.~ abviou.~ NN cord-005646-xhx9pzhj 2085 23 ! ! . cord-005646-xhx9pzhj 2085 24 ? ? . cord-005646-xhx9pzhj 2086 1 ece ece NNP cord-005646-xhx9pzhj 2086 2 ~ ~ NFP cord-005646-xhx9pzhj 2086 3 siB siB NNP cord-005646-xhx9pzhj 2086 4 ; ; : cord-005646-xhx9pzhj 2086 5 in in IN cord-005646-xhx9pzhj 2086 6 cO~.Te co~.te CD cord-005646-xhx9pzhj 2086 7 ctin ctin NNP cord-005646-xhx9pzhj 2086 8 g g NNP cord-005646-xhx9pzhj 2086 9 severe severe JJ cord-005646-xhx9pzhj 2086 10 pa~0lo2~-i pa~0lo2~-i NNP cord-005646-xhx9pzhj 2087 1 ~mnediately ~mnediately NNP cord-005646-xhx9pzhj 2087 2 f0U0wing f0u0we VBG cord-005646-xhx9pzhj 2087 3 Ne Ne NNP cord-005646-xhx9pzhj 2087 4 , , , cord-005646-xhx9pzhj 2087 5 : : : cord-005646-xhx9pzhj 2087 6 ~per,'~fion ~per,'~fion NN cord-005646-xhx9pzhj 2087 7 . . . cord-005646-xhx9pzhj 2088 1 Background background NN cord-005646-xhx9pzhj 2088 2 : : : cord-005646-xhx9pzhj 2089 1 Reconstruction reconstruction NN cord-005646-xhx9pzhj 2089 2 of of IN cord-005646-xhx9pzhj 2089 3 the the DT cord-005646-xhx9pzhj 2089 4 heart heart NN cord-005646-xhx9pzhj 2089 5 by by IN cord-005646-xhx9pzhj 2089 6 three three CD cord-005646-xhx9pzhj 2089 7 - - HYPH cord-005646-xhx9pzhj 2089 8 dimensional dimensional JJ cord-005646-xhx9pzhj 2089 9 ( ( -LRB- cord-005646-xhx9pzhj 2089 10 3D 3D NNP cord-005646-xhx9pzhj 2089 11 ) ) -RRB- cord-005646-xhx9pzhj 2089 12 echocardiography echocardiography NN cord-005646-xhx9pzhj 2089 13 provided provide VBD cord-005646-xhx9pzhj 2089 14 new new JJ cord-005646-xhx9pzhj 2089 15 information information NN cord-005646-xhx9pzhj 2089 16 on on IN cord-005646-xhx9pzhj 2089 17 anatomy anatomy NN cord-005646-xhx9pzhj 2089 18 of of IN cord-005646-xhx9pzhj 2089 19 complex complex JJ cord-005646-xhx9pzhj 2089 20 congenital congenital JJ cord-005646-xhx9pzhj 2089 21 heart heart NN cord-005646-xhx9pzhj 2089 22 defects defect NNS cord-005646-xhx9pzhj 2089 23 , , , cord-005646-xhx9pzhj 2089 24 We -PRON- PRP cord-005646-xhx9pzhj 2089 25 assessed assess VBD cord-005646-xhx9pzhj 2089 26 the the DT cord-005646-xhx9pzhj 2089 27 utility utility NN cord-005646-xhx9pzhj 2089 28 of of IN cord-005646-xhx9pzhj 2089 29 3D 3D NNP cord-005646-xhx9pzhj 2089 30 ultrasound ultrasound NN cord-005646-xhx9pzhj 2089 31 in in IN cord-005646-xhx9pzhj 2089 32 detecting detect VBG cord-005646-xhx9pzhj 2089 33 morphological morphological JJ cord-005646-xhx9pzhj 2089 34 changes change NNS cord-005646-xhx9pzhj 2089 35 in in IN cord-005646-xhx9pzhj 2089 36 cerebral cerebral JJ cord-005646-xhx9pzhj 2089 37 anatomy anatomy NN cord-005646-xhx9pzhj 2089 38 in in IN cord-005646-xhx9pzhj 2089 39 newborns newborn NNS cord-005646-xhx9pzhj 2089 40 before before IN cord-005646-xhx9pzhj 2089 41 and and CC cord-005646-xhx9pzhj 2089 42 after after IN cord-005646-xhx9pzhj 2089 43 cardiac cardiac JJ cord-005646-xhx9pzhj 2089 44 surgery surgery NN cord-005646-xhx9pzhj 2089 45 . . . cord-005646-xhx9pzhj 2090 1 Methods method NNS cord-005646-xhx9pzhj 2090 2 : : : cord-005646-xhx9pzhj 2091 1 Transfontanel Transfontanel NNP cord-005646-xhx9pzhj 2091 2 cross cross JJ cord-005646-xhx9pzhj 2091 3 - - JJ cord-005646-xhx9pzhj 2091 4 sectional sectional JJ cord-005646-xhx9pzhj 2091 5 ultrasound ultrasound NN cord-005646-xhx9pzhj 2091 6 , , , cord-005646-xhx9pzhj 2091 7 scans scan NNS cord-005646-xhx9pzhj 2091 8 were be VBD cord-005646-xhx9pzhj 2091 9 obtained obtain VBN cord-005646-xhx9pzhj 2091 10 in in IN cord-005646-xhx9pzhj 2091 11 standardized standardized JJ cord-005646-xhx9pzhj 2091 12 coronal coronal JJ cord-005646-xhx9pzhj 2091 13 and and CC cord-005646-xhx9pzhj 2091 14 median median JJ cord-005646-xhx9pzhj 2091 15 sagittal sagittal JJ cord-005646-xhx9pzhj 2091 16 planes plane NNS cord-005646-xhx9pzhj 2091 17 . . . cord-005646-xhx9pzhj 2092 1 Subsequently subsequently RB cord-005646-xhx9pzhj 2092 2 , , , cord-005646-xhx9pzhj 2092 3 rotational rotational JJ cord-005646-xhx9pzhj 2092 4 scanning scanning NN cord-005646-xhx9pzhj 2092 5 was be VBD cord-005646-xhx9pzhj 2092 6 used use VBN cord-005646-xhx9pzhj 2092 7 to to TO cord-005646-xhx9pzhj 2092 8 acquire acquire VB cord-005646-xhx9pzhj 2092 9 the the DT cord-005646-xhx9pzhj 2092 10 multiple multiple JJ cord-005646-xhx9pzhj 2092 11 sequential sequential JJ cord-005646-xhx9pzhj 2092 12 crosssections crosssection NNS cord-005646-xhx9pzhj 2092 13 of of IN cord-005646-xhx9pzhj 2092 14 the the DT cord-005646-xhx9pzhj 2092 15 brain brain NN cord-005646-xhx9pzhj 2092 16 . . . cord-005646-xhx9pzhj 2093 1 For for IN cord-005646-xhx9pzhj 2093 2 rotational rotational JJ cord-005646-xhx9pzhj 2093 3 scanning scanning NN cord-005646-xhx9pzhj 2093 4 , , , cord-005646-xhx9pzhj 2093 5 a a DT cord-005646-xhx9pzhj 2093 6 conventional conventional JJ cord-005646-xhx9pzhj 2093 7 5 5 CD cord-005646-xhx9pzhj 2093 8 MHz MHz NNS cord-005646-xhx9pzhj 2093 9 transducer transducer NN cord-005646-xhx9pzhj 2093 10 was be VBD cord-005646-xhx9pzhj 2093 11 rotated rotate VBN cord-005646-xhx9pzhj 2093 12 180 180 CD cord-005646-xhx9pzhj 2093 13 degrees degree NNS cord-005646-xhx9pzhj 2093 14 . . . cord-005646-xhx9pzhj 2094 1 Scanning scanning NN cord-005646-xhx9pzhj 2094 2 took take VBD cord-005646-xhx9pzhj 2094 3 less less JJR cord-005646-xhx9pzhj 2094 4 than than IN cord-005646-xhx9pzhj 2094 5 one one CD cord-005646-xhx9pzhj 2094 6 minute minute NN cord-005646-xhx9pzhj 2094 7 and and CC cord-005646-xhx9pzhj 2094 8 required require VBD cord-005646-xhx9pzhj 2094 9 no no DT cord-005646-xhx9pzhj 2094 10 sedation sedation NN cord-005646-xhx9pzhj 2094 11 , , , cord-005646-xhx9pzhj 2094 12 Data Data NNP cord-005646-xhx9pzhj 2094 13 was be VBD cord-005646-xhx9pzhj 2094 14 stored store VBN cord-005646-xhx9pzhj 2094 15 in in IN cord-005646-xhx9pzhj 2094 16 the the DT cord-005646-xhx9pzhj 2094 17 image image NN cord-005646-xhx9pzhj 2094 18 processing processing NN cord-005646-xhx9pzhj 2094 19 computer computer NN cord-005646-xhx9pzhj 2094 20 which which WDT cord-005646-xhx9pzhj 2094 21 allowed allow VBD cord-005646-xhx9pzhj 2094 22 for for IN cord-005646-xhx9pzhj 2094 23 off off IN cord-005646-xhx9pzhj 2094 24 - - HYPH cord-005646-xhx9pzhj 2094 25 line line NN cord-005646-xhx9pzhj 2094 26 three three CD cord-005646-xhx9pzhj 2094 27 dimensional dimensional JJ cord-005646-xhx9pzhj 2094 28 reconstruction reconstruction NN cord-005646-xhx9pzhj 2094 29 of of IN cord-005646-xhx9pzhj 2094 30 different different JJ cord-005646-xhx9pzhj 2094 31 brain brain NN cord-005646-xhx9pzhj 2094 32 regions region NNS cord-005646-xhx9pzhj 2094 33 . . . cord-005646-xhx9pzhj 2095 1 Twelve twelve CD cord-005646-xhx9pzhj 2095 2 infants infant NNS cord-005646-xhx9pzhj 2095 3 aged age VBN cord-005646-xhx9pzhj 2095 4 3 3 CD cord-005646-xhx9pzhj 2095 5 -21 -21 NN cord-005646-xhx9pzhj 2095 6 ( ( -LRB- cord-005646-xhx9pzhj 2095 7 median median JJ cord-005646-xhx9pzhj 2095 8 7 7 CD cord-005646-xhx9pzhj 2095 9 ) ) -RRB- cord-005646-xhx9pzhj 2095 10 days day NNS cord-005646-xhx9pzhj 2095 11 were be VBD cord-005646-xhx9pzhj 2095 12 assessed assess VBN cord-005646-xhx9pzhj 2095 13 before before IN cord-005646-xhx9pzhj 2095 14 and and CC cord-005646-xhx9pzhj 2095 15 after after IN cord-005646-xhx9pzhj 2095 16 cardiac cardiac JJ cord-005646-xhx9pzhj 2095 17 surgery surgery NN cord-005646-xhx9pzhj 2095 18 , , , cord-005646-xhx9pzhj 2095 19 Results result NNS cord-005646-xhx9pzhj 2095 20 : : : cord-005646-xhx9pzhj 2095 21 Cavity cavity NN cord-005646-xhx9pzhj 2095 22 of of IN cord-005646-xhx9pzhj 2095 23 lateral lateral JJ cord-005646-xhx9pzhj 2095 24 ventricle ventricle NN cord-005646-xhx9pzhj 2095 25 , , , cord-005646-xhx9pzhj 2095 26 choroid choroid NN cord-005646-xhx9pzhj 2095 27 plexus plexus NN cord-005646-xhx9pzhj 2095 28 and and CC cord-005646-xhx9pzhj 2095 29 the the DT cord-005646-xhx9pzhj 2095 30 periventricular periventricular NNP cord-005646-xhx9pzhj 2095 31 brain brain NN cord-005646-xhx9pzhj 2095 32 parenchyma parenchyma NN cord-005646-xhx9pzhj 2095 33 could could MD cord-005646-xhx9pzhj 2095 34 be be VB cord-005646-xhx9pzhj 2095 35 reconstructed reconstruct VBN cord-005646-xhx9pzhj 2095 36 in in IN cord-005646-xhx9pzhj 2095 37 all all DT cord-005646-xhx9pzhj 2095 38 . . . cord-005646-xhx9pzhj 2096 1 Accurate accurate JJ cord-005646-xhx9pzhj 2096 2 estimation estimation NN cord-005646-xhx9pzhj 2096 3 of of IN cord-005646-xhx9pzhj 2096 4 size size NN cord-005646-xhx9pzhj 2096 5 and and CC cord-005646-xhx9pzhj 2096 6 volume volume NN cord-005646-xhx9pzhj 2096 7 of of IN cord-005646-xhx9pzhj 2096 8 lateral lateral JJ cord-005646-xhx9pzhj 2096 9 ventricle ventricle NN cord-005646-xhx9pzhj 2096 10 , , , cord-005646-xhx9pzhj 2096 11 aqueduct aqueduct NN cord-005646-xhx9pzhj 2096 12 , , , cord-005646-xhx9pzhj 2096 13 and and CC cord-005646-xhx9pzhj 2096 14 other other JJ cord-005646-xhx9pzhj 2096 15 ultrasonographic ultrasonographic JJ cord-005646-xhx9pzhj 2096 16 visible visible JJ cord-005646-xhx9pzhj 2096 17 pathological pathological JJ cord-005646-xhx9pzhj 2096 18 brain brain NN cord-005646-xhx9pzhj 2096 19 lesions lesion NNS cord-005646-xhx9pzhj 2096 20 could could MD cord-005646-xhx9pzhj 2096 21 be be VB cord-005646-xhx9pzhj 2096 22 performed perform VBN cord-005646-xhx9pzhj 2096 23 . . . cord-005646-xhx9pzhj 2097 1 Reconstruction reconstruction NN cord-005646-xhx9pzhj 2097 2 of of IN cord-005646-xhx9pzhj 2097 3 various various JJ cord-005646-xhx9pzhj 2097 4 brain brain NN cord-005646-xhx9pzhj 2097 5 areas area NNS cord-005646-xhx9pzhj 2097 6 was be VBD cord-005646-xhx9pzhj 2097 7 accomplished accomplish VBN cord-005646-xhx9pzhj 2097 8 in in IN cord-005646-xhx9pzhj 2097 9 3 3 CD cord-005646-xhx9pzhj 2097 10 - - SYM cord-005646-xhx9pzhj 2097 11 10 10 CD cord-005646-xhx9pzhj 2097 12 minutes minute NNS cord-005646-xhx9pzhj 2097 13 . . . cord-005646-xhx9pzhj 2098 1 The the DT cord-005646-xhx9pzhj 2098 2 localisation localisation NN cord-005646-xhx9pzhj 2098 3 and and CC cord-005646-xhx9pzhj 2098 4 extension extension NN cord-005646-xhx9pzhj 2098 5 of of IN cord-005646-xhx9pzhj 2098 6 severe severe JJ cord-005646-xhx9pzhj 2098 7 periventricular periventricular JJ cord-005646-xhx9pzhj 2098 8 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 2098 9 which which WDT cord-005646-xhx9pzhj 2098 10 was be VBD cord-005646-xhx9pzhj 2098 11 detected detect VBN cord-005646-xhx9pzhj 2098 12 preoperatively preoperatively RB cord-005646-xhx9pzhj 2098 13 in in IN cord-005646-xhx9pzhj 2098 14 one one CD cord-005646-xhx9pzhj 2098 15 infants infant NNS cord-005646-xhx9pzhj 2098 16 was be VBD cord-005646-xhx9pzhj 2098 17 better well RBR cord-005646-xhx9pzhj 2098 18 visualized visualize VBN cord-005646-xhx9pzhj 2098 19 than than IN cord-005646-xhx9pzhj 2098 20 in in IN cord-005646-xhx9pzhj 2098 21 conventional conventional JJ cord-005646-xhx9pzhj 2098 22 ultrasonography ultrasonography NN cord-005646-xhx9pzhj 2098 23 . . . cord-005646-xhx9pzhj 2099 1 Epicortical Epicortical NNP cord-005646-xhx9pzhj 2099 2 and and CC cord-005646-xhx9pzhj 2099 3 subarachnoidal subarachnoidal JJ cord-005646-xhx9pzhj 2099 4 space space NN cord-005646-xhx9pzhj 2099 5 could could MD cord-005646-xhx9pzhj 2099 6 be be VB cord-005646-xhx9pzhj 2099 7 reconstructed reconstruct VBN cord-005646-xhx9pzhj 2099 8 in in IN cord-005646-xhx9pzhj 2099 9 all all DT cord-005646-xhx9pzhj 2099 10 and and CC cord-005646-xhx9pzhj 2099 11 allowed allow VBN cord-005646-xhx9pzhj 2099 12 detection detection NN cord-005646-xhx9pzhj 2099 13 of of IN cord-005646-xhx9pzhj 2099 14 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 2099 15 in in IN cord-005646-xhx9pzhj 2099 16 one one CD cord-005646-xhx9pzhj 2099 17 case case NN cord-005646-xhx9pzhj 2099 18 which which WDT cord-005646-xhx9pzhj 2099 19 was be VBD cord-005646-xhx9pzhj 2099 20 not not RB cord-005646-xhx9pzhj 2099 21 detected detect VBN cord-005646-xhx9pzhj 2099 22 by by IN cord-005646-xhx9pzhj 2099 23 conventional conventional JJ cord-005646-xhx9pzhj 2099 24 ultrasound ultrasound NN cord-005646-xhx9pzhj 2099 25 . . . cord-005646-xhx9pzhj 2100 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2100 2 : : : cord-005646-xhx9pzhj 2101 1 3D 3d JJ cord-005646-xhx9pzhj 2101 2 reconstruction reconstruction NN cord-005646-xhx9pzhj 2101 3 of of IN cord-005646-xhx9pzhj 2101 4 different different JJ cord-005646-xhx9pzhj 2101 5 areas area NNS cord-005646-xhx9pzhj 2101 6 of of IN cord-005646-xhx9pzhj 2101 7 the the DT cord-005646-xhx9pzhj 2101 8 brain brain NN cord-005646-xhx9pzhj 2101 9 may may MD cord-005646-xhx9pzhj 2101 10 provide provide VB cord-005646-xhx9pzhj 2101 11 additional additional JJ cord-005646-xhx9pzhj 2101 12 quantitative quantitative JJ cord-005646-xhx9pzhj 2101 13 information information NN cord-005646-xhx9pzhj 2101 14 on on IN cord-005646-xhx9pzhj 2101 15 size size NN cord-005646-xhx9pzhj 2101 16 and and CC cord-005646-xhx9pzhj 2101 17 volume volume NN cord-005646-xhx9pzhj 2101 18 of of IN cord-005646-xhx9pzhj 2101 19 the the DT cord-005646-xhx9pzhj 2101 20 internal internal JJ cord-005646-xhx9pzhj 2101 21 ventricle ventricle NN cord-005646-xhx9pzhj 2101 22 and and CC cord-005646-xhx9pzhj 2101 23 choroid choroid NN cord-005646-xhx9pzhj 2101 24 plexus plexus NN cord-005646-xhx9pzhj 2101 25 , , , cord-005646-xhx9pzhj 2101 26 and and CC cord-005646-xhx9pzhj 2101 27 better well JJR cord-005646-xhx9pzhj 2101 28 understanding understanding NN cord-005646-xhx9pzhj 2101 29 of of IN cord-005646-xhx9pzhj 2101 30 the the DT cord-005646-xhx9pzhj 2101 31 topographical topographical JJ cord-005646-xhx9pzhj 2101 32 aspects aspect NNS cord-005646-xhx9pzhj 2101 33 and and CC cord-005646-xhx9pzhj 2101 34 the the DT cord-005646-xhx9pzhj 2101 35 extension extension NN cord-005646-xhx9pzhj 2101 36 of of IN cord-005646-xhx9pzhj 2101 37 intra intra NNP cord-005646-xhx9pzhj 2101 38 - - : cord-005646-xhx9pzhj 2101 39 and and CC cord-005646-xhx9pzhj 2101 40 periventricular periventricular JJ cord-005646-xhx9pzhj 2101 41 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 2101 42 than than IN cord-005646-xhx9pzhj 2101 43 conventional conventional JJ cord-005646-xhx9pzhj 2101 44 cross cross JJ cord-005646-xhx9pzhj 2101 45 - - JJ cord-005646-xhx9pzhj 2101 46 sectional sectional JJ cord-005646-xhx9pzhj 2101 47 ultrasound ultrasound NN cord-005646-xhx9pzhj 2101 48 . . . cord-005646-xhx9pzhj 2102 1 Introduction introduction NN cord-005646-xhx9pzhj 2102 2 : : : cord-005646-xhx9pzhj 2103 1 Intracranial intracranial JJ cord-005646-xhx9pzhj 2103 2 cerebral cerebral JJ cord-005646-xhx9pzhj 2103 3 blood blood NN cord-005646-xhx9pzhj 2103 4 has have VBZ cord-005646-xhx9pzhj 2103 5 been be VBN cord-005646-xhx9pzhj 2103 6 estimated estimate VBN cord-005646-xhx9pzhj 2103 7 to to TO cord-005646-xhx9pzhj 2103 8 be be VB cord-005646-xhx9pzhj 2103 9 70 70 CD cord-005646-xhx9pzhj 2103 10 % % NN cord-005646-xhx9pzhj 2103 11 venous venous JJ cord-005646-xhx9pzhj 2103 12 , , , cord-005646-xhx9pzhj 2103 13 The the DT cord-005646-xhx9pzhj 2103 14 invasive invasive JJ cord-005646-xhx9pzhj 2103 15 measurment measurment NN cord-005646-xhx9pzhj 2103 16 of of IN cord-005646-xhx9pzhj 2103 17 venous venous JJ cord-005646-xhx9pzhj 2103 18 blood blood NN cord-005646-xhx9pzhj 2103 19 saturation saturation NN cord-005646-xhx9pzhj 2103 20 in in IN cord-005646-xhx9pzhj 2103 21 the the DT cord-005646-xhx9pzhj 2103 22 jugular jugular NN cord-005646-xhx9pzhj 2103 23 bulb bulb NN cord-005646-xhx9pzhj 2103 24 provides provide VBZ cord-005646-xhx9pzhj 2103 25 quantitative quantitative JJ cord-005646-xhx9pzhj 2103 26 information information NN cord-005646-xhx9pzhj 2103 27 on on IN cord-005646-xhx9pzhj 2103 28 cerebral cerebral JJ cord-005646-xhx9pzhj 2103 29 oxygen oxygen NN cord-005646-xhx9pzhj 2103 30 supply supply NN cord-005646-xhx9pzhj 2103 31 and and CC cord-005646-xhx9pzhj 2103 32 consumption consumption NN cord-005646-xhx9pzhj 2103 33 . . . cord-005646-xhx9pzhj 2104 1 However however RB cord-005646-xhx9pzhj 2104 2 , , , cord-005646-xhx9pzhj 2104 3 routine routine JJ cord-005646-xhx9pzhj 2104 4 oxymetric oxymetric JJ cord-005646-xhx9pzhj 2104 5 measurement measurement NN cord-005646-xhx9pzhj 2104 6 of of IN cord-005646-xhx9pzhj 2104 7 blood blood NN cord-005646-xhx9pzhj 2104 8 saturation saturation NN cord-005646-xhx9pzhj 2104 9 in in IN cord-005646-xhx9pzhj 2104 10 the the DT cord-005646-xhx9pzhj 2104 11 jugular jugular NN cord-005646-xhx9pzhj 2104 12 bulb bulb NN cord-005646-xhx9pzhj 2104 13 by by IN cord-005646-xhx9pzhj 2104 14 insertion insertion NN cord-005646-xhx9pzhj 2104 15 of of IN cord-005646-xhx9pzhj 2104 16 a a DT cord-005646-xhx9pzhj 2104 17 catheter catheter NN cord-005646-xhx9pzhj 2104 18 line line NN cord-005646-xhx9pzhj 2104 19 into into IN cord-005646-xhx9pzhj 2104 20 the the DT cord-005646-xhx9pzhj 2104 21 internal internal JJ cord-005646-xhx9pzhj 2104 22 jugtdar jugtdar NNP cord-005646-xhx9pzhj 2104 23 vein vein NN cord-005646-xhx9pzhj 2104 24 is be VBZ cord-005646-xhx9pzhj 2104 25 an an DT cord-005646-xhx9pzhj 2104 26 invasive invasive JJ cord-005646-xhx9pzhj 2104 27 procedure procedure NN cord-005646-xhx9pzhj 2104 28 which which WDT cord-005646-xhx9pzhj 2104 29 has have VBZ cord-005646-xhx9pzhj 2104 30 limited limit VBN cord-005646-xhx9pzhj 2104 31 use use NN cord-005646-xhx9pzhj 2104 32 especially especially RB cord-005646-xhx9pzhj 2104 33 in in IN cord-005646-xhx9pzhj 2104 34 infants infant NNS cord-005646-xhx9pzhj 2104 35 and and CC cord-005646-xhx9pzhj 2104 36 young young JJ cord-005646-xhx9pzhj 2104 37 children child NNS cord-005646-xhx9pzhj 2104 38 . . . cord-005646-xhx9pzhj 2105 1 Thus thus RB cord-005646-xhx9pzhj 2105 2 the the DT cord-005646-xhx9pzhj 2105 3 aim aim NN cord-005646-xhx9pzhj 2105 4 of of IN cord-005646-xhx9pzhj 2105 5 this this DT cord-005646-xhx9pzhj 2105 6 study study NN cord-005646-xhx9pzhj 2105 7 was be VBD cord-005646-xhx9pzhj 2105 8 to to TO cord-005646-xhx9pzhj 2105 9 investigate investigate VB cord-005646-xhx9pzhj 2105 10 the the DT cord-005646-xhx9pzhj 2105 11 correlation correlation NN cord-005646-xhx9pzhj 2105 12 between between IN cord-005646-xhx9pzhj 2105 13 the the DT cord-005646-xhx9pzhj 2105 14 non non JJ cord-005646-xhx9pzhj 2105 15 - - JJ cord-005646-xhx9pzhj 2105 16 invasive invasive JJ cord-005646-xhx9pzhj 2105 17 spectroscopic spectroscopic JJ cord-005646-xhx9pzhj 2105 18 measurement measurement NN cord-005646-xhx9pzhj 2105 19 of of IN cord-005646-xhx9pzhj 2105 20 rSO2 rSO2 NNP cord-005646-xhx9pzhj 2105 21 and and CC cord-005646-xhx9pzhj 2105 22 the the DT cord-005646-xhx9pzhj 2105 23 oxymetric oxymetric JJ cord-005646-xhx9pzhj 2105 24 determination determination NN cord-005646-xhx9pzhj 2105 25 of of IN cord-005646-xhx9pzhj 2105 26 the the DT cord-005646-xhx9pzhj 2105 27 blood blood NN cord-005646-xhx9pzhj 2105 28 saturation saturation NN cord-005646-xhx9pzhj 2105 29 in in IN cord-005646-xhx9pzhj 2105 30 the the DT cord-005646-xhx9pzhj 2105 31 jugular jugular NN cord-005646-xhx9pzhj 2105 32 bulb bulb NN cord-005646-xhx9pzhj 2105 33 in in IN cord-005646-xhx9pzhj 2105 34 infants infant NNS cord-005646-xhx9pzhj 2105 35 and and CC cord-005646-xhx9pzhj 2105 36 children child NNS cord-005646-xhx9pzhj 2105 37 undergoing undergo VBG cord-005646-xhx9pzhj 2105 38 routine routine JJ cord-005646-xhx9pzhj 2105 39 cardiac cardiac JJ cord-005646-xhx9pzhj 2105 40 catheterization catheterization NN cord-005646-xhx9pzhj 2105 41 .. .. . cord-005646-xhx9pzhj 2106 1 Methods method NNS cord-005646-xhx9pzhj 2106 2 : : : cord-005646-xhx9pzhj 2106 3 During during IN cord-005646-xhx9pzhj 2106 4 routine routine JJ cord-005646-xhx9pzhj 2106 5 cardiac cardiac JJ cord-005646-xhx9pzhj 2106 6 catheterization catheterization NN cord-005646-xhx9pzhj 2106 7 30 30 CD cord-005646-xhx9pzhj 2106 8 infants infant NNS cord-005646-xhx9pzhj 2106 9 and and CC cord-005646-xhx9pzhj 2106 10 children child NNS cord-005646-xhx9pzhj 2106 11 ( ( -LRB- cord-005646-xhx9pzhj 2106 12 age age NN cord-005646-xhx9pzhj 2106 13 5 5 CD cord-005646-xhx9pzhj 2106 14 day-16 day-16 NNP cord-005646-xhx9pzhj 2106 15 year year NN cord-005646-xhx9pzhj 2106 16 , , , cord-005646-xhx9pzhj 2106 17 median median NN cord-005646-xhx9pzhj 2106 18 4,5 4,5 CD cord-005646-xhx9pzhj 2106 19 year year NN cord-005646-xhx9pzhj 2106 20 ) ) -RRB- cord-005646-xhx9pzhj 2107 1 the the DT cord-005646-xhx9pzhj 2107 2 rSO2 rSO2 NNP cord-005646-xhx9pzhj 2107 3 was be VBD cord-005646-xhx9pzhj 2107 4 measured measure VBN cord-005646-xhx9pzhj 2107 5 continuously continuously RB cord-005646-xhx9pzhj 2107 6 using use VBG cord-005646-xhx9pzhj 2107 7 a a DT cord-005646-xhx9pzhj 2107 8 two two CD cord-005646-xhx9pzhj 2107 9 chanel chanel NNP cord-005646-xhx9pzhj 2107 10 cerebral cerebral NNP cord-005646-xhx9pzhj 2107 11 oxymeter oxymeter NNP cord-005646-xhx9pzhj 2107 12 ( ( -LRB- cord-005646-xhx9pzhj 2107 13 INVOS INVOS NNP cord-005646-xhx9pzhj 2107 14 3100A 3100A NNP cord-005646-xhx9pzhj 2107 15 ) ) -RRB- cord-005646-xhx9pzhj 2107 16 . . . cord-005646-xhx9pzhj 2108 1 The the DT cord-005646-xhx9pzhj 2108 2 sensor sensor NN cord-005646-xhx9pzhj 2108 3 was be VBD cord-005646-xhx9pzhj 2108 4 placed place VBN cord-005646-xhx9pzhj 2108 5 in in IN cord-005646-xhx9pzhj 2108 6 standardized standardized JJ cord-005646-xhx9pzhj 2108 7 location location NN cord-005646-xhx9pzhj 2108 8 at at IN cord-005646-xhx9pzhj 2108 9 the the DT cord-005646-xhx9pzhj 2108 10 left left JJ cord-005646-xhx9pzhj 2108 11 temporal temporal JJ cord-005646-xhx9pzhj 2108 12 head head NN cord-005646-xhx9pzhj 2108 13 side side NN cord-005646-xhx9pzhj 2108 14 . . . cord-005646-xhx9pzhj 2109 1 After after IN cord-005646-xhx9pzhj 2109 2 the the DT cord-005646-xhx9pzhj 2109 3 routine routine JJ cord-005646-xhx9pzhj 2109 4 oxymetric oxymetric JJ cord-005646-xhx9pzhj 2109 5 blood blood NN cord-005646-xhx9pzhj 2109 6 sampling sampling NN cord-005646-xhx9pzhj 2109 7 in in IN cord-005646-xhx9pzhj 2109 8 the the DT cord-005646-xhx9pzhj 2109 9 superior superior JJ cord-005646-xhx9pzhj 2109 10 vena vena FW cord-005646-xhx9pzhj 2109 11 cava cava FW cord-005646-xhx9pzhj 2109 12 the the DT cord-005646-xhx9pzhj 2109 13 oxymetric oxymetric JJ cord-005646-xhx9pzhj 2109 14 catheter catheter NN cord-005646-xhx9pzhj 2109 15 was be VBD cord-005646-xhx9pzhj 2109 16 manupilated manupilate VBN cord-005646-xhx9pzhj 2109 17 into into IN cord-005646-xhx9pzhj 2109 18 the the DT cord-005646-xhx9pzhj 2109 19 left left JJ cord-005646-xhx9pzhj 2109 20 jugular jugular NN cord-005646-xhx9pzhj 2109 21 bulb bulb NN cord-005646-xhx9pzhj 2109 22 . . . cord-005646-xhx9pzhj 2110 1 After after IN cord-005646-xhx9pzhj 2110 2 control control NN cord-005646-xhx9pzhj 2110 3 of of IN cord-005646-xhx9pzhj 2110 4 the the DT cord-005646-xhx9pzhj 2110 5 catheter catheter NN cord-005646-xhx9pzhj 2110 6 position position NN cord-005646-xhx9pzhj 2110 7 simultenuous simultenuous JJ cord-005646-xhx9pzhj 2110 8 values value NNS cord-005646-xhx9pzhj 2110 9 of of IN cord-005646-xhx9pzhj 2110 10 the the DT cord-005646-xhx9pzhj 2110 11 rSO2 rSO2 NNP cord-005646-xhx9pzhj 2110 12 were be VBD cord-005646-xhx9pzhj 2110 13 documented document VBN cord-005646-xhx9pzhj 2110 14 . . . cord-005646-xhx9pzhj 2111 1 Results result NNS cord-005646-xhx9pzhj 2111 2 : : : cord-005646-xhx9pzhj 2111 3 Over over IN cord-005646-xhx9pzhj 2111 4 a a DT cord-005646-xhx9pzhj 2111 5 range range NN cord-005646-xhx9pzhj 2111 6 of of IN cord-005646-xhx9pzhj 2111 7 ( ( -LRB- cord-005646-xhx9pzhj 2111 8 33 33 CD cord-005646-xhx9pzhj 2111 9 - - SYM cord-005646-xhx9pzhj 2111 10 87 87 CD cord-005646-xhx9pzhj 2111 11 % % NN cord-005646-xhx9pzhj 2111 12 ) ) -RRB- cord-005646-xhx9pzhj 2111 13 SjO2 sjo2 NN cord-005646-xhx9pzhj 2111 14 , , , cord-005646-xhx9pzhj 2111 15 a a DT cord-005646-xhx9pzhj 2111 16 significant significant JJ cord-005646-xhx9pzhj 2111 17 linear linear JJ cord-005646-xhx9pzhj 2111 18 correlation correlation NN cord-005646-xhx9pzhj 2111 19 was be VBD cord-005646-xhx9pzhj 2111 20 found find VBN cord-005646-xhx9pzhj 2111 21 between between IN cord-005646-xhx9pzhj 2111 22 the the DT cord-005646-xhx9pzhj 2111 23 spectroscopic spectroscopic JJ cord-005646-xhx9pzhj 2111 24 measurement measurement NN cord-005646-xhx9pzhj 2111 25 of of IN cord-005646-xhx9pzhj 2111 26 rSO2 rSO2 NNP cord-005646-xhx9pzhj 2111 27 and and CC cord-005646-xhx9pzhj 2111 28 the the DT cord-005646-xhx9pzhj 2111 29 oxymetric oxymetric JJ cord-005646-xhx9pzhj 2111 30 determination determination NN cord-005646-xhx9pzhj 2111 31 of of IN cord-005646-xhx9pzhj 2111 32 venous venous JJ cord-005646-xhx9pzhj 2111 33 blood blood NN cord-005646-xhx9pzhj 2111 34 saturation saturation NN cord-005646-xhx9pzhj 2111 35 in in IN cord-005646-xhx9pzhj 2111 36 the the DT cord-005646-xhx9pzhj 2111 37 jugular jugular NN cord-005646-xhx9pzhj 2111 38 bulb bulb NN cord-005646-xhx9pzhj 2111 39 ( ( -LRB- cord-005646-xhx9pzhj 2111 40 r=0,83 r=0,83 NNP cord-005646-xhx9pzhj 2111 41 , , , cord-005646-xhx9pzhj 2111 42 p<0,001 p<0,001 NNP cord-005646-xhx9pzhj 2111 43 ) ) -RRB- cord-005646-xhx9pzhj 2111 44 and and CC cord-005646-xhx9pzhj 2111 45 the the DT cord-005646-xhx9pzhj 2111 46 superior superior JJ cord-005646-xhx9pzhj 2111 47 vena vena FW cord-005646-xhx9pzhj 2111 48 cava cava FW cord-005646-xhx9pzhj 2111 49 ( ( -LRB- cord-005646-xhx9pzhj 2111 50 r=0,65 r=0,65 NNP cord-005646-xhx9pzhj 2111 51 , , , cord-005646-xhx9pzhj 2111 52 p<0,05 p<0,05 NNP cord-005646-xhx9pzhj 2111 53 ) ) -RRB- cord-005646-xhx9pzhj 2111 54 . . . cord-005646-xhx9pzhj 2112 1 No no DT cord-005646-xhx9pzhj 2112 2 significant significant JJ cord-005646-xhx9pzhj 2112 3 correlation correlation NN cord-005646-xhx9pzhj 2112 4 was be VBD cord-005646-xhx9pzhj 2112 5 found find VBN cord-005646-xhx9pzhj 2112 6 between between IN cord-005646-xhx9pzhj 2112 7 rSO2 rSO2 NNP cord-005646-xhx9pzhj 2112 8 and and CC cord-005646-xhx9pzhj 2112 9 the the DT cord-005646-xhx9pzhj 2112 10 arterial arterial JJ cord-005646-xhx9pzhj 2112 11 blood blood NN cord-005646-xhx9pzhj 2112 12 saturation saturation NN cord-005646-xhx9pzhj 2112 13 in in IN cord-005646-xhx9pzhj 2112 14 the the DT cord-005646-xhx9pzhj 2112 15 descending descend VBG cord-005646-xhx9pzhj 2112 16 aorta aorta NN cord-005646-xhx9pzhj 2112 17 and and CC cord-005646-xhx9pzhj 2112 18 as as RB cord-005646-xhx9pzhj 2112 19 well well RB cord-005646-xhx9pzhj 2112 20 as as IN cord-005646-xhx9pzhj 2112 21 to to IN cord-005646-xhx9pzhj 2112 22 the the DT cord-005646-xhx9pzhj 2112 23 standared standare VBN cord-005646-xhx9pzhj 2112 24 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 2112 25 parameters parameter NNS cord-005646-xhx9pzhj 2112 26 . . . cord-005646-xhx9pzhj 2113 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2113 2 : : : cord-005646-xhx9pzhj 2113 3 Meusurement Meusurement NNP cord-005646-xhx9pzhj 2113 4 of of IN cord-005646-xhx9pzhj 2114 1 rSO2 rSO2 NNP cord-005646-xhx9pzhj 2114 2 by by IN cord-005646-xhx9pzhj 2114 3 MRS MRS NNP cord-005646-xhx9pzhj 2114 4 may may MD cord-005646-xhx9pzhj 2114 5 provide provide VB cord-005646-xhx9pzhj 2114 6 continuous continuous JJ cord-005646-xhx9pzhj 2114 7 non non JJ cord-005646-xhx9pzhj 2114 8 - - JJ cord-005646-xhx9pzhj 2114 9 invasive invasive JJ cord-005646-xhx9pzhj 2114 10 information information NN cord-005646-xhx9pzhj 2114 11 on on IN cord-005646-xhx9pzhj 2114 12 cerebral cerebral JJ cord-005646-xhx9pzhj 2114 13 venous venous JJ cord-005646-xhx9pzhj 2114 14 blood blood NN cord-005646-xhx9pzhj 2114 15 saturation saturation NN cord-005646-xhx9pzhj 2114 16 and and CC cord-005646-xhx9pzhj 2114 17 thereby thereby RB cord-005646-xhx9pzhj 2114 18 possibly possibly RB cord-005646-xhx9pzhj 2114 19 on on IN cord-005646-xhx9pzhj 2114 20 cerebral cerebral JJ cord-005646-xhx9pzhj 2114 21 oxygen oxygen NN cord-005646-xhx9pzhj 2114 22 supply supply NN cord-005646-xhx9pzhj 2114 23 and and CC cord-005646-xhx9pzhj 2114 24 consumption consumption NN cord-005646-xhx9pzhj 2114 25 in in IN cord-005646-xhx9pzhj 2114 26 infants infant NNS cord-005646-xhx9pzhj 2114 27 and and CC cord-005646-xhx9pzhj 2114 28 children child NNS cord-005646-xhx9pzhj 2114 29 . . . cord-005646-xhx9pzhj 2115 1 These these DT cord-005646-xhx9pzhj 2115 2 may may MD cord-005646-xhx9pzhj 2115 3 be be VB cord-005646-xhx9pzhj 2115 4 of of IN cord-005646-xhx9pzhj 2115 5 clinical clinical JJ cord-005646-xhx9pzhj 2115 6 value value NN cord-005646-xhx9pzhj 2115 7 particulary particulary JJ cord-005646-xhx9pzhj 2115 8 during during IN cord-005646-xhx9pzhj 2115 9 and and CC cord-005646-xhx9pzhj 2115 10 immediately immediately RB cord-005646-xhx9pzhj 2115 11 after after IN cord-005646-xhx9pzhj 2115 12 heart heart NN cord-005646-xhx9pzhj 2115 13 surgery surgery NN cord-005646-xhx9pzhj 2115 14 by by IN cord-005646-xhx9pzhj 2115 15 means mean NNS cord-005646-xhx9pzhj 2115 16 of of IN cord-005646-xhx9pzhj 2115 17 non non JJ cord-005646-xhx9pzhj 2115 18 - - JJ cord-005646-xhx9pzhj 2115 19 pulsatile pulsatile JJ cord-005646-xhx9pzhj 2115 20 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 2115 21 bypass bypass NN cord-005646-xhx9pzhj 2115 22 . . . cord-005646-xhx9pzhj 2115 23 _SP cord-005646-xhx9pzhj 2116 1 Information information NN cord-005646-xhx9pzhj 2116 2 on on IN cord-005646-xhx9pzhj 2116 3 refractory refractory JJ cord-005646-xhx9pzhj 2116 4 status status NN cord-005646-xhx9pzhj 2116 5 epilepticus epilepticus NN cord-005646-xhx9pzhj 2116 6 ( ( -LRB- cord-005646-xhx9pzhj 2116 7 RSE RSE NNP cord-005646-xhx9pzhj 2116 8 ) ) -RRB- cord-005646-xhx9pzhj 2116 9 from from IN cord-005646-xhx9pzhj 2116 10 developing develop VBG cord-005646-xhx9pzhj 2116 11 countries country NNS cord-005646-xhx9pzhj 2116 12 is be VBZ cord-005646-xhx9pzhj 2116 13 scarce scarce JJ cord-005646-xhx9pzhj 2116 14 . . . cord-005646-xhx9pzhj 2117 1 We -PRON- PRP cord-005646-xhx9pzhj 2117 2 analysed analyse VBD cord-005646-xhx9pzhj 2117 3 43 43 CD cord-005646-xhx9pzhj 2117 4 cases case NNS cord-005646-xhx9pzhj 2117 5 of of IN cord-005646-xhx9pzhj 2117 6 RSE RSE NNP cord-005646-xhx9pzhj 2117 7 admitted admit VBN cord-005646-xhx9pzhj 2117 8 over over IN cord-005646-xhx9pzhj 2117 9 last last JJ cord-005646-xhx9pzhj 2117 10 2 2 CD cord-005646-xhx9pzhj 2117 11 yrs yrs NN cord-005646-xhx9pzhj 2117 12 . . . cord-005646-xhx9pzhj 2118 1 The the DT cord-005646-xhx9pzhj 2118 2 objective objective NN cord-005646-xhx9pzhj 2118 3 was be VBD cord-005646-xhx9pzhj 2118 4 to to TO cord-005646-xhx9pzhj 2118 5 study study VB cord-005646-xhx9pzhj 2118 6 etiology etiology NN cord-005646-xhx9pzhj 2118 7 end end NN cord-005646-xhx9pzhj 2118 8 evaluate evaluate VB cord-005646-xhx9pzhj 2118 9 efficacy efficacy NN cord-005646-xhx9pzhj 2118 10 of of IN cord-005646-xhx9pzhj 2118 11 diezepam diezepam NN cord-005646-xhx9pzhj 2118 12 infusion infusion NN cord-005646-xhx9pzhj 2118 13 . . . cord-005646-xhx9pzhj 2119 1 Median median JJ cord-005646-xhx9pzhj 2119 2 age age NN cord-005646-xhx9pzhj 2119 3 of of IN cord-005646-xhx9pzhj 2119 4 the the DT cord-005646-xhx9pzhj 2119 5 patients patient NNS cord-005646-xhx9pzhj 2119 6 was be VBD cord-005646-xhx9pzhj 2120 1 1.25 1.25 CD cord-005646-xhx9pzhj 2120 2 years year NNS cord-005646-xhx9pzhj 2120 3 Irange Irange NNP cord-005646-xhx9pzhj 2120 4 1.5 1.5 CD cord-005646-xhx9pzhj 2120 5 months month NNS cord-005646-xhx9pzhj 2120 6 to to IN cord-005646-xhx9pzhj 2120 7 t t NNP cord-005646-xhx9pzhj 2120 8 1.5 1.5 CD cord-005646-xhx9pzhj 2120 9 yrs yr NNS cord-005646-xhx9pzhj 2120 10 ) ) -RRB- cord-005646-xhx9pzhj 2120 11 ; ; : cord-005646-xhx9pzhj 2120 12 70 70 CD cord-005646-xhx9pzhj 2120 13 % % NN cord-005646-xhx9pzhj 2120 14 were be VBD cord-005646-xhx9pzhj 2120 15 boys boy NNS cord-005646-xhx9pzhj 2120 16 . . . cord-005646-xhx9pzhj 2121 1 Onset onset NN cord-005646-xhx9pzhj 2121 2 of of IN cord-005646-xhx9pzhj 2121 3 seizures seizure NNS cord-005646-xhx9pzhj 2121 4 was be VBD cord-005646-xhx9pzhj 2121 5 1-t44 1-t44 CD cord-005646-xhx9pzhj 2121 6 hours hour NNS cord-005646-xhx9pzhj 2121 7 ( ( -LRB- cord-005646-xhx9pzhj 2121 8 median median JJ cord-005646-xhx9pzhj 2121 9 24 24 CD cord-005646-xhx9pzhj 2121 10 hours hour NNS cord-005646-xhx9pzhj 2121 11 ) ) -RRB- cord-005646-xhx9pzhj 2121 12 prior prior RB cord-005646-xhx9pzhj 2121 13 to to IN cord-005646-xhx9pzhj 2121 14 hespitalisation hespitalisation NN cord-005646-xhx9pzhj 2121 15 . . . cord-005646-xhx9pzhj 2122 1 The the DT cord-005646-xhx9pzhj 2122 2 Glasgow Glasgow NNP cord-005646-xhx9pzhj 2122 3 Coma Coma NNP cord-005646-xhx9pzhj 2122 4 Scale Scale NNP cord-005646-xhx9pzhj 2122 5 score score NN cord-005646-xhx9pzhj 2122 6 ranged range VBD cord-005646-xhx9pzhj 2122 7 from from IN cord-005646-xhx9pzhj 2122 8 3.11 3.11 CD cord-005646-xhx9pzhj 2122 9 ( ( -LRB- cord-005646-xhx9pzhj 2123 1 mean+SD mean+SD NNP cord-005646-xhx9pzhj 2123 2 5 5 CD cord-005646-xhx9pzhj 2123 3 + + SYM cord-005646-xhx9pzhj 2123 4 2 2 CD cord-005646-xhx9pzhj 2123 5 ) ) -RRB- cord-005646-xhx9pzhj 2123 6 . . . cord-005646-xhx9pzhj 2124 1 The the DT cord-005646-xhx9pzhj 2124 2 commonest common JJS cord-005646-xhx9pzhj 2124 3 underlying underlying JJ cord-005646-xhx9pzhj 2124 4 causes cause NNS cord-005646-xhx9pzhj 2124 5 were be VBD cord-005646-xhx9pzhj 2124 6 acute acute JJ cord-005646-xhx9pzhj 2124 7 CNS CNS NNP cord-005646-xhx9pzhj 2124 8 infections infection NNS cord-005646-xhx9pzhj 2124 9 ( ( -LRB- cord-005646-xhx9pzhj 2124 10 26/43 26/43 CD cord-005646-xhx9pzhj 2124 11 , , , cord-005646-xhx9pzhj 2124 12 60 60 CD cord-005646-xhx9pzhj 2124 13 % % NN cord-005646-xhx9pzhj 2124 14 ; ; , cord-005646-xhx9pzhj 2124 15 bacterial bacterial JJ cord-005646-xhx9pzhj 2124 16 meningitis meningitis NN cord-005646-xhx9pzhj 2124 17 , , , cord-005646-xhx9pzhj 2124 18 16 16 CD cord-005646-xhx9pzhj 2124 19 , , , cord-005646-xhx9pzhj 2124 20 encephalitis encephalitis RB cord-005646-xhx9pzhj 2124 21 , , , cord-005646-xhx9pzhj 2124 22 10 10 CD cord-005646-xhx9pzhj 2124 23 ) ) -RRB- cord-005646-xhx9pzhj 2124 24 and and CC cord-005646-xhx9pzhj 2124 25 epilepsy epilepsy NN cord-005646-xhx9pzhj 2124 26 ( ( -LRB- cord-005646-xhx9pzhj 2124 27 8/43 8/43 CD cord-005646-xhx9pzhj 2124 28 , , , cord-005646-xhx9pzhj 2124 29 10 10 CD cord-005646-xhx9pzhj 2124 30 % % NN cord-005646-xhx9pzhj 2124 31 ) ) -RRB- cord-005646-xhx9pzhj 2124 32 . . . cord-005646-xhx9pzhj 2125 1 Oiazepam oiazepam NN cord-005646-xhx9pzhj 2125 2 infusion infusion NN cord-005646-xhx9pzhj 2125 3 in in IN cord-005646-xhx9pzhj 2125 4 incremental incremental JJ cord-005646-xhx9pzhj 2125 5 dose dose NN cord-005646-xhx9pzhj 2126 1 ( ( -LRB- cord-005646-xhx9pzhj 2126 2 range range VBP cord-005646-xhx9pzhj 2126 3 0.01 0.01 CD cord-005646-xhx9pzhj 2126 4 - - SYM cord-005646-xhx9pzhj 2126 5 0.025 0.025 CD cord-005646-xhx9pzhj 2126 6 mg mg NNP cord-005646-xhx9pzhj 2126 7 / / SYM cord-005646-xhx9pzhj 2126 8 kg kg NNP cord-005646-xhx9pzhj 2126 9 / / SYM cord-005646-xhx9pzhj 2126 10 min min NNP cord-005646-xhx9pzhj 2126 11 ) ) -RRB- cord-005646-xhx9pzhj 2126 12 was be VBD cord-005646-xhx9pzhj 2126 13 used use VBN cord-005646-xhx9pzhj 2126 14 in in IN cord-005646-xhx9pzhj 2126 15 38 38 CD cord-005646-xhx9pzhj 2126 16 patients patient NNS cord-005646-xhx9pzhj 2126 17 over over IN cord-005646-xhx9pzhj 2126 18 3.4_+2.1 3.4_+2.1 CD cord-005646-xhx9pzhj 2126 19 days day NNS cord-005646-xhx9pzhj 2126 20 . . . cord-005646-xhx9pzhj 2127 1 Seizures seizure NNS cord-005646-xhx9pzhj 2127 2 were be VBD cord-005646-xhx9pzhj 2127 3 controlled control VBN cord-005646-xhx9pzhj 2127 4 n n NN cord-005646-xhx9pzhj 2127 5 31 31 CD cord-005646-xhx9pzhj 2127 6 ( ( -LRB- cord-005646-xhx9pzhj 2127 7 82 82 CD cord-005646-xhx9pzhj 2127 8 % % NN cord-005646-xhx9pzhj 2127 9 ) ) -RRB- cord-005646-xhx9pzhj 2127 10 , , , cord-005646-xhx9pzhj 2127 11 Mechanical mechanical JJ cord-005646-xhx9pzhj 2127 12 ventilation ventilation NN cord-005646-xhx9pzhj 2127 13 was be VBD cord-005646-xhx9pzhj 2127 14 required require VBN cord-005646-xhx9pzhj 2127 15 in in IN cord-005646-xhx9pzhj 2127 16 10 10 CD cord-005646-xhx9pzhj 2127 17 ( ( -LRB- cord-005646-xhx9pzhj 2127 18 26%)only 26%)only NNP cord-005646-xhx9pzhj 2127 19 , , , cord-005646-xhx9pzhj 2127 20 while while IN cord-005646-xhx9pzhj 2127 21 none none NN cord-005646-xhx9pzhj 2127 22 had have VBD cord-005646-xhx9pzhj 2127 23 hypotension hypotension NN cord-005646-xhx9pzhj 2127 24 ; ; : cord-005646-xhx9pzhj 2127 25 84 84 CD cord-005646-xhx9pzhj 2127 26 % % NN cord-005646-xhx9pzhj 2127 27 patients patient NNS cord-005646-xhx9pzhj 2127 28 survived survive VBD cord-005646-xhx9pzhj 2127 29 . . . cord-005646-xhx9pzhj 2128 1 Thiopental thiopental JJ cord-005646-xhx9pzhj 2128 2 infusion infusion NN cord-005646-xhx9pzhj 2128 3 ( ( -LRB- cord-005646-xhx9pzhj 2128 4 holus holus NNP cord-005646-xhx9pzhj 2128 5 5 5 CD cord-005646-xhx9pzhj 2128 6 mg mg NNP cord-005646-xhx9pzhj 2128 7 / / SYM cord-005646-xhx9pzhj 2128 8 kg kg NNS cord-005646-xhx9pzhj 2128 9 followed follow VBD cord-005646-xhx9pzhj 2128 10 by by IN cord-005646-xhx9pzhj 2128 11 0.2 0.2 CD cord-005646-xhx9pzhj 2128 12 mglkg mglkg NN cord-005646-xhx9pzhj 2128 13 / / SYM cord-005646-xhx9pzhj 2128 14 min min NNP cord-005646-xhx9pzhj 2128 15 , , , cord-005646-xhx9pzhj 2128 16 and and CC cord-005646-xhx9pzhj 2128 17 increments increment NNS cord-005646-xhx9pzhj 2128 18 of of IN cord-005646-xhx9pzhj 2128 19 0.1 0.1 CD cord-005646-xhx9pzhj 2128 20 mg mg NNP cord-005646-xhx9pzhj 2128 21 / / SYM cord-005646-xhx9pzhj 2128 22 kg kg NNP cord-005646-xhx9pzhj 2128 23 / / SYM cord-005646-xhx9pzhj 2128 24 min min NN cord-005646-xhx9pzhj 2128 25 till till IN cord-005646-xhx9pzhj 2128 26 seizure seizure NN cord-005646-xhx9pzhj 2128 27 control control NN cord-005646-xhx9pzhj 2128 28 ) ) -RRB- cord-005646-xhx9pzhj 2128 29 was be VBD cord-005646-xhx9pzhj 2128 30 used use VBN cord-005646-xhx9pzhj 2128 31 in in IN cord-005646-xhx9pzhj 2128 32 8 8 CD cord-005646-xhx9pzhj 2128 33 patients patient NNS cord-005646-xhx9pzhj 2128 34 over over IN cord-005646-xhx9pzhj 2128 35 1.7_+0.7 1.7_+0.7 CD cord-005646-xhx9pzhj 2128 36 days day NNS cord-005646-xhx9pzhj 2128 37 ; ; : cord-005646-xhx9pzhj 2128 38 seizure seizure NN cord-005646-xhx9pzhj 2128 39 were be VBD cord-005646-xhx9pzhj 2128 40 controlled control VBN cord-005646-xhx9pzhj 2128 41 in in IN cord-005646-xhx9pzhj 2128 42 all all DT cord-005646-xhx9pzhj 2128 43 , , , cord-005646-xhx9pzhj 2128 44 but but CC cord-005646-xhx9pzhj 2128 45 five five CD cord-005646-xhx9pzhj 2128 46 patients patient NNS cord-005646-xhx9pzhj 2128 47 needed need VBD cord-005646-xhx9pzhj 2128 48 mechanical mechanical JJ cord-005646-xhx9pzhj 2128 49 ventilation ventilation NN cord-005646-xhx9pzhj 2129 1 , , , cord-005646-xhx9pzhj 2129 2 six six CD cord-005646-xhx9pzhj 2129 3 developed develop VBN cord-005646-xhx9pzhj 2129 4 hypotension hypotension NN cord-005646-xhx9pzhj 2129 5 needing need VBG cord-005646-xhx9pzhj 2129 6 infusion infusion NN cord-005646-xhx9pzhj 2129 7 of of IN cord-005646-xhx9pzhj 2129 8 vasopressoi vasopressoi NNP cord-005646-xhx9pzhj 2129 9 drugs drug NNS cord-005646-xhx9pzhj 2129 10 , , , cord-005646-xhx9pzhj 2129 11 3 3 CD cord-005646-xhx9pzhj 2129 12 out out IN cord-005646-xhx9pzhj 2129 13 of of IN cord-005646-xhx9pzhj 2129 14 8 8 CD cord-005646-xhx9pzhj 2129 15 ( ( -LRB- cord-005646-xhx9pzhj 2129 16 38 38 CD cord-005646-xhx9pzhj 2129 17 % % NN cord-005646-xhx9pzhj 2129 18 ) ) -RRB- cord-005646-xhx9pzhj 2129 19 died die VBD cord-005646-xhx9pzhj 2129 20 , , , cord-005646-xhx9pzhj 2129 21 Overall overall JJ cord-005646-xhx9pzhj 2129 22 mortality mortality NN cord-005646-xhx9pzhj 2129 23 was be VBD cord-005646-xhx9pzhj 2129 24 26 26 CD cord-005646-xhx9pzhj 2129 25 % % NN cord-005646-xhx9pzhj 2129 26 , , , cord-005646-xhx9pzhj 2129 27 mainly mainly RB cord-005646-xhx9pzhj 2129 28 due due JJ cord-005646-xhx9pzhj 2129 29 to to IN cord-005646-xhx9pzhj 2129 30 acute acute JJ cord-005646-xhx9pzhj 2129 31 CNS CNS NNP cord-005646-xhx9pzhj 2129 32 infections infection NNS cord-005646-xhx9pzhj 2129 33 ( ( -LRB- cord-005646-xhx9pzhj 2129 34 n-6 n-6 NNP cord-005646-xhx9pzhj 2129 35 ) ) -RRB- cord-005646-xhx9pzhj 2129 36 and and CC cord-005646-xhx9pzhj 2129 37 prolonged prolong VBN cord-005646-xhx9pzhj 2129 38 SE SE NNP cord-005646-xhx9pzhj 2129 39 . . . cord-005646-xhx9pzhj 2130 1 The the DT cord-005646-xhx9pzhj 2130 2 patient patient NN cord-005646-xhx9pzhj 2130 3 was be VBD cord-005646-xhx9pzhj 2130 4 a a DT cord-005646-xhx9pzhj 2130 5 2-year 2-year CD cord-005646-xhx9pzhj 2130 6 - - HYPH cord-005646-xhx9pzhj 2130 7 old old JJ cord-005646-xhx9pzhj 2130 8 gift gift NN cord-005646-xhx9pzhj 2130 9 di di NN cord-005646-xhx9pzhj 2130 10 ~ ~ CD cord-005646-xhx9pzhj 2130 11 aosed aose VBN cord-005646-xhx9pzhj 2130 12 of of IN cord-005646-xhx9pzhj 2130 13 Dov,~ Dov,~ NNP cord-005646-xhx9pzhj 2130 14 's 's POS cord-005646-xhx9pzhj 2130 15 s s NN cord-005646-xhx9pzhj 2130 16 ~ ~ NNP cord-005646-xhx9pzhj 2130 17 drom¢ drom¢ NN cord-005646-xhx9pzhj 2130 18 , , , cord-005646-xhx9pzhj 2130 19 Tetralogy Tetralogy NNP cord-005646-xhx9pzhj 2130 20 of of IN cord-005646-xhx9pzhj 2130 21 Fallot Fallot NNP cord-005646-xhx9pzhj 2130 22 . . . cord-005646-xhx9pzhj 2131 1 ( ( -LRB- cord-005646-xhx9pzhj 2131 2 T.F. T.F. NNP cord-005646-xhx9pzhj 2131 3 ) ) -RRB- cord-005646-xhx9pzhj 2132 1 Before before IN cord-005646-xhx9pzhj 2132 2 admission admission NN cord-005646-xhx9pzhj 2132 3 a a DT cord-005646-xhx9pzhj 2132 4 vasovagal vasovagal JJ cord-005646-xhx9pzhj 2132 5 crisis crisis NN cord-005646-xhx9pzhj 2132 6 after after IN cord-005646-xhx9pzhj 2132 7 coughing cough VBG cord-005646-xhx9pzhj 2132 8 and and CC cord-005646-xhx9pzhj 2132 9 vomiting vomiting NN cord-005646-xhx9pzhj 2132 10 was be VBD cord-005646-xhx9pzhj 2132 11 seen see VBN cord-005646-xhx9pzhj 2132 12 , , , cord-005646-xhx9pzhj 2132 13 and and CC cord-005646-xhx9pzhj 2132 14 she -PRON- PRP cord-005646-xhx9pzhj 2132 15 was be VBD cord-005646-xhx9pzhj 2132 16 taken take VBN cord-005646-xhx9pzhj 2132 17 to to IN cord-005646-xhx9pzhj 2132 18 the the DT cord-005646-xhx9pzhj 2132 19 emergency emergency NN cord-005646-xhx9pzhj 2132 20 room room NN cord-005646-xhx9pzhj 2132 21 . . . cord-005646-xhx9pzhj 2133 1 Mother mother NN cord-005646-xhx9pzhj 2133 2 said say VBD cord-005646-xhx9pzhj 2133 3 she -PRON- PRP cord-005646-xhx9pzhj 2133 4 had have VBD cord-005646-xhx9pzhj 2133 5 eyanosis eyanosis NN cord-005646-xhx9pzhj 2133 6 in in IN cord-005646-xhx9pzhj 2133 7 the the DT cord-005646-xhx9pzhj 2133 8 mucous mucous JJ cord-005646-xhx9pzhj 2133 9 membranes membrane NNS cord-005646-xhx9pzhj 2133 10 of of IN cord-005646-xhx9pzhj 2133 11 the the DT cord-005646-xhx9pzhj 2133 12 mouth mouth NN cord-005646-xhx9pzhj 2133 13 with with IN cord-005646-xhx9pzhj 2133 14 exercise exercise NN cord-005646-xhx9pzhj 2133 15 . . . cord-005646-xhx9pzhj 2134 1 On on IN cord-005646-xhx9pzhj 2134 2 physical physical JJ cord-005646-xhx9pzhj 2134 3 examination examination NN cord-005646-xhx9pzhj 2134 4 , , , cord-005646-xhx9pzhj 2134 5 she -PRON- PRP cord-005646-xhx9pzhj 2134 6 ~as ~a VBZ cord-005646-xhx9pzhj 2134 7 afebrile afebrile NNP cord-005646-xhx9pzhj 2134 8 , , , cord-005646-xhx9pzhj 2134 9 normal normal JJ cord-005646-xhx9pzhj 2134 10 fundi fundus NNS cord-005646-xhx9pzhj 2134 11 and and CC cord-005646-xhx9pzhj 2134 12 neurologic neurologic JJ cord-005646-xhx9pzhj 2134 13 examination examination NN cord-005646-xhx9pzhj 2134 14 was be VBD cord-005646-xhx9pzhj 2134 15 normal normal JJ cord-005646-xhx9pzhj 2134 16 . . . cord-005646-xhx9pzhj 2135 1 A a DT cord-005646-xhx9pzhj 2135 2 harsh harsh JJ cord-005646-xhx9pzhj 2135 3 systolic systolic JJ cord-005646-xhx9pzhj 2135 4 murmur murmur NN cord-005646-xhx9pzhj 2135 5 was be VBD cord-005646-xhx9pzhj 2135 6 hear~ hear~ VBN cord-005646-xhx9pzhj 2135 7 with with IN cord-005646-xhx9pzhj 2135 8 decrased decrased JJ cord-005646-xhx9pzhj 2135 9 intensity intensity NN cord-005646-xhx9pzhj 2135 10 during during IN cord-005646-xhx9pzhj 2135 11 bradycardia bradycardia NN cord-005646-xhx9pzhj 2135 12 . . . cord-005646-xhx9pzhj 2136 1 Chest Chest NNP cord-005646-xhx9pzhj 2136 2 RX RX NNP cord-005646-xhx9pzhj 2136 3 disclosed disclose VBD cord-005646-xhx9pzhj 2136 4 a a DT cord-005646-xhx9pzhj 2136 5 decreased decrease VBN cord-005646-xhx9pzhj 2136 6 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2136 7 vascular vascular JJ cord-005646-xhx9pzhj 2136 8 markings marking NNS cord-005646-xhx9pzhj 2136 9 . . . cord-005646-xhx9pzhj 2137 1 ECG ECG NNP cord-005646-xhx9pzhj 2137 2 : : : cord-005646-xhx9pzhj 2137 3 synus synus NN cord-005646-xhx9pzhj 2137 4 rhythm rhythm NN cord-005646-xhx9pzhj 2137 5 , , , cord-005646-xhx9pzhj 2137 6 with with IN cord-005646-xhx9pzhj 2137 7 bradycardia bradycardia NN cord-005646-xhx9pzhj 2137 8 and and CC cord-005646-xhx9pzhj 2137 9 nodal nodal JJ cord-005646-xhx9pzhj 2137 10 escape escape NN cord-005646-xhx9pzhj 2137 11 rhyflmas rhyflmas NNP cord-005646-xhx9pzhj 2137 12 . . . cord-005646-xhx9pzhj 2138 1 She -PRON- PRP cord-005646-xhx9pzhj 2138 2 was be VBD cord-005646-xhx9pzhj 2138 3 transferred transfer VBN cord-005646-xhx9pzhj 2138 4 to to IN cord-005646-xhx9pzhj 2138 5 our -PRON- PRP$ cord-005646-xhx9pzhj 2138 6 PICU PICU NNP cord-005646-xhx9pzhj 2138 7 because because IN cord-005646-xhx9pzhj 2138 8 of of IN cord-005646-xhx9pzhj 2138 9 severe severe JJ cord-005646-xhx9pzhj 2138 10 h3,pertomc h3,pertomc NN cord-005646-xhx9pzhj 2138 11 seizure seizure NN cord-005646-xhx9pzhj 2138 12 , , , cord-005646-xhx9pzhj 2138 13 lost lose VBD cord-005646-xhx9pzhj 2138 14 conciousness conciousness NN cord-005646-xhx9pzhj 2138 15 , , , cord-005646-xhx9pzhj 2138 16 and and CC cord-005646-xhx9pzhj 2138 17 deeembrate deeembrate NNP cord-005646-xhx9pzhj 2138 18 poslamng~ poslamng~ NNP cord-005646-xhx9pzhj 2139 1 ~t ~t IN cord-005646-xhx9pzhj 2139 2 cyancx cyancx NNP cord-005646-xhx9pzhj 2139 3 ~ ~ NFP cord-005646-xhx9pzhj 2139 4 is be VBZ cord-005646-xhx9pzhj 2139 5 . . . cord-005646-xhx9pzhj 2140 1 The the DT cord-005646-xhx9pzhj 2140 2 episode episode NN cord-005646-xhx9pzhj 2140 3 lasted last VBD cord-005646-xhx9pzhj 2140 4 for for IN cord-005646-xhx9pzhj 2140 5 ~weral ~weral JJ cord-005646-xhx9pzhj 2140 6 seconds second NNS cord-005646-xhx9pzhj 2140 7 , , , cord-005646-xhx9pzhj 2140 8 and and CC cord-005646-xhx9pzhj 2140 9 ceased cease VBD cord-005646-xhx9pzhj 2140 10 v v NN cord-005646-xhx9pzhj 2140 11 ~ ~ NFP cord-005646-xhx9pzhj 2140 12 th th XX cord-005646-xhx9pzhj 2140 13 diazepam diazepam NN cord-005646-xhx9pzhj 2140 14 . . . cord-005646-xhx9pzhj 2141 1 On on IN cord-005646-xhx9pzhj 2141 2 admission admission NN cord-005646-xhx9pzhj 2141 3 she -PRON- PRP cord-005646-xhx9pzhj 2141 4 was be VBD cord-005646-xhx9pzhj 2141 5 lethargy lethargy NN cord-005646-xhx9pzhj 2141 6 , , , cord-005646-xhx9pzhj 2141 7 and and CC cord-005646-xhx9pzhj 2141 8 neurologlc neurologlc JJ cord-005646-xhx9pzhj 2141 9 exammation exammation NN cord-005646-xhx9pzhj 2141 10 showed show VBD cord-005646-xhx9pzhj 2141 11 weakness weakness NN cord-005646-xhx9pzhj 2141 12 of of IN cord-005646-xhx9pzhj 2141 13 left left JJ cord-005646-xhx9pzhj 2141 14 leg leg NN cord-005646-xhx9pzhj 2141 15 without without IN cord-005646-xhx9pzhj 2141 16 Babinski Babinski NNP cord-005646-xhx9pzhj 2141 17 , , , cord-005646-xhx9pzhj 2141 18 and and CC cord-005646-xhx9pzhj 2141 19 normal normal JJ cord-005646-xhx9pzhj 2141 20 funduscopic funduscopic NN cord-005646-xhx9pzhj 2141 21 . . . cord-005646-xhx9pzhj 2142 1 The the DT cord-005646-xhx9pzhj 2142 2 patient patient NN cord-005646-xhx9pzhj 2142 3 had have VBD cord-005646-xhx9pzhj 2142 4 two two CD cord-005646-xhx9pzhj 2142 5 episodes episode NNS cord-005646-xhx9pzhj 2142 6 of of IN cord-005646-xhx9pzhj 2142 7 bradycardia bradycardia NN cord-005646-xhx9pzhj 2142 8 and and CC cord-005646-xhx9pzhj 2142 9 isoproterenol isoproterenol NNP cord-005646-xhx9pzhj 2142 10 was be VBD cord-005646-xhx9pzhj 2142 11 begun begin VBN cord-005646-xhx9pzhj 2142 12 . . . cord-005646-xhx9pzhj 2143 1 During during IN cord-005646-xhx9pzhj 2143 2 those those DT cord-005646-xhx9pzhj 2143 3 episodes episode NNS cord-005646-xhx9pzhj 2143 4 the the DT cord-005646-xhx9pzhj 2143 5 patient patient NN cord-005646-xhx9pzhj 2143 6 was be VBD cord-005646-xhx9pzhj 2143 7 cyanotic cyanotic JJ cord-005646-xhx9pzhj 2143 8 , , , cord-005646-xhx9pzhj 2143 9 and and CC cord-005646-xhx9pzhj 2143 10 the the DT cord-005646-xhx9pzhj 2143 11 murmur murmur NN cord-005646-xhx9pzhj 2143 12 was be VBD cord-005646-xhx9pzhj 2143 13 heard hear VBN cord-005646-xhx9pzhj 2143 14 with with IN cord-005646-xhx9pzhj 2143 15 the the DT cord-005646-xhx9pzhj 2143 16 same same JJ cord-005646-xhx9pzhj 2143 17 intensity intensity NN cord-005646-xhx9pzhj 2143 18 . . . cord-005646-xhx9pzhj 2144 1 ACT ACT NNP cord-005646-xhx9pzhj 2144 2 scan scan NNP cord-005646-xhx9pzhj 2144 3 disclosed disclose VBD cord-005646-xhx9pzhj 2144 4 a a DT cord-005646-xhx9pzhj 2144 5 tight tight JJ cord-005646-xhx9pzhj 2144 6 parieto parieto NN cord-005646-xhx9pzhj 2144 7 - - HYPH cord-005646-xhx9pzhj 2144 8 temporai temporai NNP cord-005646-xhx9pzhj 2144 9 abscess abscess NN cord-005646-xhx9pzhj 2144 10 with with IN cord-005646-xhx9pzhj 2144 11 midline midline JJ cord-005646-xhx9pzhj 2144 12 shift shift NN cord-005646-xhx9pzhj 2144 13 , , , cord-005646-xhx9pzhj 2144 14 lnmediately lnmediately RB cord-005646-xhx9pzhj 2144 15 after after IN cord-005646-xhx9pzhj 2144 16 the the DT cord-005646-xhx9pzhj 2144 17 diagnostic diagnostic JJ cord-005646-xhx9pzhj 2144 18 CT CT NNP cord-005646-xhx9pzhj 2144 19 , , , cord-005646-xhx9pzhj 2144 20 we -PRON- PRP cord-005646-xhx9pzhj 2144 21 administered administer VBD cord-005646-xhx9pzhj 2144 22 antibiotics antibiotic NNS cord-005646-xhx9pzhj 2144 23 , , , cord-005646-xhx9pzhj 2144 24 antiedema antiedema NN cord-005646-xhx9pzhj 2144 25 treatment treatment NN cord-005646-xhx9pzhj 2145 1 and and CC cord-005646-xhx9pzhj 2145 2 it -PRON- PRP cord-005646-xhx9pzhj 2145 3 was be VBD cord-005646-xhx9pzhj 2145 4 drained drain VBN cord-005646-xhx9pzhj 2145 5 . . . cord-005646-xhx9pzhj 2146 1 The the DT cord-005646-xhx9pzhj 2146 2 abscess abscess NN cord-005646-xhx9pzhj 2146 3 culture culture NN cord-005646-xhx9pzhj 2146 4 was be VBD cord-005646-xhx9pzhj 2146 5 negative negative JJ cord-005646-xhx9pzhj 2146 6 . . . cord-005646-xhx9pzhj 2147 1 A a DT cord-005646-xhx9pzhj 2147 2 CT CT NNP cord-005646-xhx9pzhj 2147 3 control control NN cord-005646-xhx9pzhj 2147 4 disclosed disclose VBD cord-005646-xhx9pzhj 2147 5 air air NN cord-005646-xhx9pzhj 2147 6 and and CC cord-005646-xhx9pzhj 2147 7 midlme midlme NNP cord-005646-xhx9pzhj 2147 8 shift shift NN cord-005646-xhx9pzhj 2147 9 . . . cord-005646-xhx9pzhj 2148 1 ~ ~ NFP cord-005646-xhx9pzhj 2148 2 the the DT cord-005646-xhx9pzhj 2148 3 next next JJ cord-005646-xhx9pzhj 2148 4 two two CD cord-005646-xhx9pzhj 2148 5 days day NNS cord-005646-xhx9pzhj 2148 6 she -PRON- PRP cord-005646-xhx9pzhj 2148 7 had have VBD cord-005646-xhx9pzhj 2148 8 three three CD cord-005646-xhx9pzhj 2148 9 episodes episode NNS cord-005646-xhx9pzhj 2148 10 of of IN cord-005646-xhx9pzhj 2148 11 h39oxia h39oxia NNP cord-005646-xhx9pzhj 2148 12 and and CC cord-005646-xhx9pzhj 2148 13 c'yauosis c'yauosis NNP cord-005646-xhx9pzhj 2148 14 ceased cease VBD cord-005646-xhx9pzhj 2148 15 with with IN cord-005646-xhx9pzhj 2148 16 o@gen o@gen NNP cord-005646-xhx9pzhj 2148 17 , , , cord-005646-xhx9pzhj 2148 18 morphine morphine NN cord-005646-xhx9pzhj 2148 19 and and CC cord-005646-xhx9pzhj 2148 20 propanoloL propanoloL NNP cord-005646-xhx9pzhj 2149 1 The the DT cord-005646-xhx9pzhj 2149 2 patient patient NN cord-005646-xhx9pzhj 2149 3 died die VBD cord-005646-xhx9pzhj 2149 4 during during IN cord-005646-xhx9pzhj 2149 5 a a DT cord-005646-xhx9pzhj 2149 6 fourth fourth JJ cord-005646-xhx9pzhj 2149 7 episode episode NN cord-005646-xhx9pzhj 2149 8 . . . cord-005646-xhx9pzhj 2150 1 DISCUSSION discussion NN cord-005646-xhx9pzhj 2150 2 : : : cord-005646-xhx9pzhj 2151 1 Arrhytmias Arrhytmias NNP cord-005646-xhx9pzhj 2151 2 are be VBP cord-005646-xhx9pzhj 2151 3 uncommon uncommon JJ cord-005646-xhx9pzhj 2151 4 in in IN cord-005646-xhx9pzhj 2151 5 patients patient NNS cord-005646-xhx9pzhj 2151 6 with with IN cord-005646-xhx9pzhj 2151 7 Tetralogy Tetralogy NNP cord-005646-xhx9pzhj 2151 8 of of IN cord-005646-xhx9pzhj 2151 9 Fallot Fallot NNP cord-005646-xhx9pzhj 2151 10 before before IN cord-005646-xhx9pzhj 2151 11 surgery surgery NN cord-005646-xhx9pzhj 2151 12 . . . cord-005646-xhx9pzhj 2152 1 In in IN cord-005646-xhx9pzhj 2152 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2152 3 case case NN cord-005646-xhx9pzhj 2152 4 the the DT cord-005646-xhx9pzhj 2152 5 first first JJ cord-005646-xhx9pzhj 2152 6 diagnosis diagnosis NN cord-005646-xhx9pzhj 2152 7 was be VBD cord-005646-xhx9pzhj 2152 8 sick sick JJ cord-005646-xhx9pzhj 2152 9 sinus sinus NN cord-005646-xhx9pzhj 2152 10 syndrome syndrome NN cord-005646-xhx9pzhj 2152 11 vs vs IN cord-005646-xhx9pzhj 2152 12 bradycardia bradycardia JJ cord-005646-xhx9pzhj 2152 13 secondary secondary JJ cord-005646-xhx9pzhj 2152 14 to to IN cord-005646-xhx9pzhj 2152 15 cyanotic cyanotic JJ cord-005646-xhx9pzhj 2152 16 episodes episode NNS cord-005646-xhx9pzhj 2152 17 . . . cord-005646-xhx9pzhj 2153 1 The the DT cord-005646-xhx9pzhj 2153 2 incidence incidence NN cord-005646-xhx9pzhj 2153 3 of of IN cord-005646-xhx9pzhj 2153 4 cerebral cerebral JJ cord-005646-xhx9pzhj 2153 5 abscess abscess NN cord-005646-xhx9pzhj 2153 6 in in IN cord-005646-xhx9pzhj 2153 7 children child NNS cord-005646-xhx9pzhj 2153 8 with with IN cord-005646-xhx9pzhj 2153 9 congenital congenital JJ cord-005646-xhx9pzhj 2153 10 heart heart NN cord-005646-xhx9pzhj 2153 11 disease disease NN cord-005646-xhx9pzhj 2153 12 ( ( -LRB- cord-005646-xhx9pzhj 2153 13 CHD CHD NNP cord-005646-xhx9pzhj 2153 14 ) ) -RRB- cord-005646-xhx9pzhj 2153 15 is be VBZ cord-005646-xhx9pzhj 2153 16 approximately approximately RB cord-005646-xhx9pzhj 2153 17 5 5 CD cord-005646-xhx9pzhj 2153 18 % % NN cord-005646-xhx9pzhj 2153 19 . . . cord-005646-xhx9pzhj 2154 1 Tetralogy tetralogy NN cord-005646-xhx9pzhj 2154 2 of of IN cord-005646-xhx9pzhj 2154 3 Fallot Fallot NNP cord-005646-xhx9pzhj 2154 4 is be VBZ cord-005646-xhx9pzhj 2154 5 the the DT cord-005646-xhx9pzhj 2154 6 most most RBS cord-005646-xhx9pzhj 2154 7 common common JJ cord-005646-xhx9pzhj 2154 8 associated associate VBN cord-005646-xhx9pzhj 2154 9 lesion lesion NN cord-005646-xhx9pzhj 2154 10 , , , cord-005646-xhx9pzhj 2154 11 and and CC cord-005646-xhx9pzhj 2154 12 is be VBZ cord-005646-xhx9pzhj 2154 13 unusual unusual JJ cord-005646-xhx9pzhj 2154 14 in in IN cord-005646-xhx9pzhj 2154 15 children child NNS cord-005646-xhx9pzhj 2154 16 under under IN cord-005646-xhx9pzhj 2154 17 2 2 CD cord-005646-xhx9pzhj 2154 18 years year NNS cord-005646-xhx9pzhj 2154 19 of of IN cord-005646-xhx9pzhj 2154 20 age age NN cord-005646-xhx9pzhj 2154 21 . . . cord-005646-xhx9pzhj 2155 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 2155 2 : : : cord-005646-xhx9pzhj 2155 3 1 1 LS cord-005646-xhx9pzhj 2155 4 ) ) -RRB- cord-005646-xhx9pzhj 2156 1 Brain brain NN cord-005646-xhx9pzhj 2156 2 abscess abscess NN cord-005646-xhx9pzhj 2156 3 is be VBZ cord-005646-xhx9pzhj 2156 4 a a DT cord-005646-xhx9pzhj 2156 5 rare rare JJ cord-005646-xhx9pzhj 2156 6 complication complication NN cord-005646-xhx9pzhj 2156 7 of of IN cord-005646-xhx9pzhj 2156 8 patients patient NNS cord-005646-xhx9pzhj 2156 9 with with IN cord-005646-xhx9pzhj 2156 10 cyanotic cyanotic JJ cord-005646-xhx9pzhj 2156 11 CHD chd NN cord-005646-xhx9pzhj 2156 12 , , , cord-005646-xhx9pzhj 2156 13 but but CC cord-005646-xhx9pzhj 2156 14 should should MD cord-005646-xhx9pzhj 2156 15 be be VB cord-005646-xhx9pzhj 2156 16 suggested suggest VBN cord-005646-xhx9pzhj 2156 17 in in IN cord-005646-xhx9pzhj 2156 18 patients patient NNS cord-005646-xhx9pzhj 2156 19 with with IN cord-005646-xhx9pzhj 2156 20 ° ° NN cord-005646-xhx9pzhj 2156 21 ' ' POS cord-005646-xhx9pzhj 2156 22 apparent apparent JJ cord-005646-xhx9pzhj 2156 23 " " `` cord-005646-xhx9pzhj 2156 24 sick sick JJ cord-005646-xhx9pzhj 2156 25 sinus sinus NN cord-005646-xhx9pzhj 2156 26 syndrome syndrome NN cord-005646-xhx9pzhj 2156 27 . . . cord-005646-xhx9pzhj 2157 1 In in IN cord-005646-xhx9pzhj 2157 2 patients patient NNS cord-005646-xhx9pzhj 2157 3 with with IN cord-005646-xhx9pzhj 2157 4 Down Down NNP cord-005646-xhx9pzhj 2157 5 's 's POS cord-005646-xhx9pzhj 2157 6 syndrome syndrome NN cord-005646-xhx9pzhj 2157 7 , , , cord-005646-xhx9pzhj 2157 8 T.F.,with T.F.,with NNP cord-005646-xhx9pzhj 2157 9 cyanotic cyanotic JJ cord-005646-xhx9pzhj 2157 10 episodes episode NNS cord-005646-xhx9pzhj 2157 11 , , , cord-005646-xhx9pzhj 2157 12 and and CC cord-005646-xhx9pzhj 2157 13 difficult difficult JJ cord-005646-xhx9pzhj 2157 14 neurologic neurologic JJ cord-005646-xhx9pzhj 2157 15 exploration exploration NN cord-005646-xhx9pzhj 2157 16 , , , cord-005646-xhx9pzhj 2157 17 a a DT cord-005646-xhx9pzhj 2157 18 brain brain NN cord-005646-xhx9pzhj 2157 19 CT CT NNP cord-005646-xhx9pzhj 2157 20 scan scan NN cord-005646-xhx9pzhj 2157 21 is be VBZ cord-005646-xhx9pzhj 2157 22 recommended recommend VBN cord-005646-xhx9pzhj 2157 23 . . . cord-005646-xhx9pzhj 2158 1 Guillain Guillain NNP cord-005646-xhx9pzhj 2158 2 - - HYPH cord-005646-xhx9pzhj 2158 3 Ba Ba NNP cord-005646-xhx9pzhj 2159 1 ~re ~re NNP cord-005646-xhx9pzhj 2159 2 syndrome syndrome NN cord-005646-xhx9pzhj 2159 3 ( ( -LRB- cord-005646-xhx9pzhj 2159 4 GBS GBS NNP cord-005646-xhx9pzhj 2159 5 ) ) -RRB- cord-005646-xhx9pzhj 2159 6 is be VBZ cord-005646-xhx9pzhj 2159 7 an an DT cord-005646-xhx9pzhj 2159 8 acute acute JJ cord-005646-xhx9pzhj 2159 9 autoimmune autoimmune JJ cord-005646-xhx9pzhj 2159 10 reaction reaction NN cord-005646-xhx9pzhj 2159 11 , , , cord-005646-xhx9pzhj 2159 12 directed direct VBD cord-005646-xhx9pzhj 2159 13 primarily primarily RB cord-005646-xhx9pzhj 2159 14 toward toward IN cord-005646-xhx9pzhj 2159 15 the the DT cord-005646-xhx9pzhj 2159 16 myelin myelin NN cord-005646-xhx9pzhj 2159 17 encasing encase VBG cord-005646-xhx9pzhj 2159 18 the the DT cord-005646-xhx9pzhj 2159 19 peripheral peripheral JJ cord-005646-xhx9pzhj 2159 20 motor motor NN cord-005646-xhx9pzhj 2159 21 nerves= nerves= NNP cord-005646-xhx9pzhj 2160 1 This this DT cord-005646-xhx9pzhj 2160 2 reaction reaction NN cord-005646-xhx9pzhj 2160 3 causes cause VBZ cord-005646-xhx9pzhj 2160 4 a a DT cord-005646-xhx9pzhj 2160 5 delay delay NN cord-005646-xhx9pzhj 2160 6 or or CC cord-005646-xhx9pzhj 2160 7 block block VB cord-005646-xhx9pzhj 2160 8 in in IN cord-005646-xhx9pzhj 2160 9 nerve nerve NN cord-005646-xhx9pzhj 2160 10 conduction conduction NN cord-005646-xhx9pzhj 2160 11 . . . cord-005646-xhx9pzhj 2161 1 The the DT cord-005646-xhx9pzhj 2161 2 presentation presentation NN cord-005646-xhx9pzhj 2161 3 often often RB cord-005646-xhx9pzhj 2161 4 can can MD cord-005646-xhx9pzhj 2161 5 be be VB cord-005646-xhx9pzhj 2161 6 very very RB cord-005646-xhx9pzhj 2161 7 subtle subtle JJ cord-005646-xhx9pzhj 2161 8 but but CC cord-005646-xhx9pzhj 2161 9 is be VBZ cord-005646-xhx9pzhj 2161 10 followed follow VBN cord-005646-xhx9pzhj 2161 11 by by IN cord-005646-xhx9pzhj 2161 12 rapid rapid JJ cord-005646-xhx9pzhj 2161 13 loss loss NN cord-005646-xhx9pzhj 2161 14 of of IN cord-005646-xhx9pzhj 2161 15 neuromuscular neuromuscular JJ cord-005646-xhx9pzhj 2161 16 power power NN cord-005646-xhx9pzhj 2161 17 , , , cord-005646-xhx9pzhj 2161 18 leading lead VBG cord-005646-xhx9pzhj 2161 19 to to IN cord-005646-xhx9pzhj 2161 20 acute acute JJ cord-005646-xhx9pzhj 2161 21 respiratory respiratory JJ cord-005646-xhx9pzhj 2161 22 distress distress NN cord-005646-xhx9pzhj 2161 23 , , , cord-005646-xhx9pzhj 2161 24 resulting result VBG cord-005646-xhx9pzhj 2161 25 from from IN cord-005646-xhx9pzhj 2161 26 weakness weakness NN cord-005646-xhx9pzhj 2161 27 of of IN cord-005646-xhx9pzhj 2161 28 muscles muscle NNS cord-005646-xhx9pzhj 2161 29 and and CC cord-005646-xhx9pzhj 2161 30 aspiration aspiration NN cord-005646-xhx9pzhj 2161 31 pneumonia pneumonia NN cord-005646-xhx9pzhj 2161 32 . . . cord-005646-xhx9pzhj 2162 1 There there EX cord-005646-xhx9pzhj 2162 2 were be VBD cord-005646-xhx9pzhj 2162 3 3 3 CD cord-005646-xhx9pzhj 2162 4 boys boy NNS cord-005646-xhx9pzhj 2162 5 -4 -4 NNP cord-005646-xhx9pzhj 2162 6 , , , cord-005646-xhx9pzhj 2162 7 8 8 CD cord-005646-xhx9pzhj 2162 8 , , , cord-005646-xhx9pzhj 2162 9 and and CC cord-005646-xhx9pzhj 2162 10 I -PRON- PRP cord-005646-xhx9pzhj 2162 11 I -PRON- PRP cord-005646-xhx9pzhj 2162 12 years year VBZ cord-005646-xhx9pzhj 2162 13 old old JJ cord-005646-xhx9pzhj 2162 14 with with IN cord-005646-xhx9pzhj 2162 15 GBS GBS NNP cord-005646-xhx9pzhj 2162 16 , , , cord-005646-xhx9pzhj 2162 17 treated treat VBN cord-005646-xhx9pzhj 2162 18 in in IN cord-005646-xhx9pzhj 2162 19 our -PRON- PRP$ cord-005646-xhx9pzhj 2162 20 ICU ICU NNP cord-005646-xhx9pzhj 2162 21 . . . cord-005646-xhx9pzhj 2163 1 Two two CD cord-005646-xhx9pzhj 2163 2 of of IN cord-005646-xhx9pzhj 2163 3 them -PRON- PRP cord-005646-xhx9pzhj 2163 4 due due JJ cord-005646-xhx9pzhj 2163 5 to to IN cord-005646-xhx9pzhj 2163 6 the the DT cord-005646-xhx9pzhj 2163 7 respiratory respiratory JJ cord-005646-xhx9pzhj 2163 8 distress distress NN cord-005646-xhx9pzhj 2163 9 were be VBD cord-005646-xhx9pzhj 2163 10 intubated intubate VBN cord-005646-xhx9pzhj 2163 11 nasotracheally nasotracheally RB cord-005646-xhx9pzhj 2163 12 and and CC cord-005646-xhx9pzhj 2163 13 ventilated ventilate VBN cord-005646-xhx9pzhj 2163 14 mechanically mechanically RB cord-005646-xhx9pzhj 2163 15 with with IN cord-005646-xhx9pzhj 2163 16 SERVO-9OOC SERVO-9OOC NNS cord-005646-xhx9pzhj 2164 1 ( ( -LRB- cord-005646-xhx9pzhj 2164 2 Siemens Siemens NNP cord-005646-xhx9pzhj 2164 3 - - HYPH cord-005646-xhx9pzhj 2164 4 Elema Elema NNP cord-005646-xhx9pzhj 2164 5 , , , cord-005646-xhx9pzhj 2164 6 Sweden Sweden NNP cord-005646-xhx9pzhj 2164 7 ) ) -RRB- cord-005646-xhx9pzhj 2164 8 ventilator ventilator NN cord-005646-xhx9pzhj 2164 9 . . . cord-005646-xhx9pzhj 2165 1 Duration duration NN cord-005646-xhx9pzhj 2165 2 of of IN cord-005646-xhx9pzhj 2165 3 ventilation ventilation NN cord-005646-xhx9pzhj 2165 4 was be VBD cord-005646-xhx9pzhj 2165 5 I -PRON- PRP cord-005646-xhx9pzhj 2165 6 I i NN cord-005646-xhx9pzhj 2165 7 and and CC cord-005646-xhx9pzhj 2165 8 34 34 CD cord-005646-xhx9pzhj 2165 9 days day NNS cord-005646-xhx9pzhj 2165 10 , , , cord-005646-xhx9pzhj 2165 11 respectively respectively RB cord-005646-xhx9pzhj 2165 12 . . . cord-005646-xhx9pzhj 2166 1 Plasma plasma NN cord-005646-xhx9pzhj 2166 2 exchange exchange NN cord-005646-xhx9pzhj 2166 3 was be VBD cord-005646-xhx9pzhj 2166 4 performed perform VBN cord-005646-xhx9pzhj 2166 5 in in IN cord-005646-xhx9pzhj 2166 6 all all DT cord-005646-xhx9pzhj 2166 7 cases case NNS cord-005646-xhx9pzhj 2166 8 . . . cord-005646-xhx9pzhj 2167 1 The the DT cord-005646-xhx9pzhj 2167 2 numbers number NNS cord-005646-xhx9pzhj 2167 3 of of IN cord-005646-xhx9pzhj 2167 4 plasma plasma NN cord-005646-xhx9pzhj 2167 5 exchange exchange NN cord-005646-xhx9pzhj 2167 6 sessions session NNS cord-005646-xhx9pzhj 2167 7 were be VBD cord-005646-xhx9pzhj 2167 8 2 2 CD cord-005646-xhx9pzhj 2167 9 - - SYM cord-005646-xhx9pzhj 2167 10 4 4 CD cord-005646-xhx9pzhj 2167 11 in in IN cord-005646-xhx9pzhj 2167 12 each each DT cord-005646-xhx9pzhj 2167 13 case case NN cord-005646-xhx9pzhj 2167 14 . . . cord-005646-xhx9pzhj 2168 1 Mean mean JJ cord-005646-xhx9pzhj 2168 2 amount amount NN cord-005646-xhx9pzhj 2168 3 of of IN cord-005646-xhx9pzhj 2168 4 plasma plasma NN cord-005646-xhx9pzhj 2168 5 exchanged exchange VBN cord-005646-xhx9pzhj 2168 6 per per IN cord-005646-xhx9pzhj 2168 7 session session NN cord-005646-xhx9pzhj 2168 8 was be VBD cord-005646-xhx9pzhj 2168 9 28,24 28,24 CD cord-005646-xhx9pzhj 2168 10 ml ml NN cord-005646-xhx9pzhj 2168 11 / / SYM cord-005646-xhx9pzhj 2168 12 kg kg NN cord-005646-xhx9pzhj 2168 13 . . . cord-005646-xhx9pzhj 2169 1 Plasma plasma NN cord-005646-xhx9pzhj 2169 2 was be VBD cord-005646-xhx9pzhj 2169 3 substituted substitute VBN cord-005646-xhx9pzhj 2169 4 with with IN cord-005646-xhx9pzhj 2169 5 albumin albumin NN cord-005646-xhx9pzhj 2169 6 , , , cord-005646-xhx9pzhj 2169 7 plasma plasma NN cord-005646-xhx9pzhj 2169 8 or or CC cord-005646-xhx9pzhj 2169 9 saline saline NN cord-005646-xhx9pzhj 2169 10 . . . cord-005646-xhx9pzhj 2170 1 The the DT cord-005646-xhx9pzhj 2170 2 most most RBS cord-005646-xhx9pzhj 2170 3 important important JJ cord-005646-xhx9pzhj 2170 4 aspect aspect NN cord-005646-xhx9pzhj 2170 5 of of IN cord-005646-xhx9pzhj 2170 6 the the DT cord-005646-xhx9pzhj 2170 7 management management NN cord-005646-xhx9pzhj 2170 8 of of IN cord-005646-xhx9pzhj 2170 9 patients patient NNS cord-005646-xhx9pzhj 2170 10 with with IN cord-005646-xhx9pzhj 2170 11 GBS GBS NNP cord-005646-xhx9pzhj 2170 12 in in IN cord-005646-xhx9pzhj 2170 13 the the DT cord-005646-xhx9pzhj 2170 14 ICU ICU NNP cord-005646-xhx9pzhj 2170 15 involves involve VBZ cord-005646-xhx9pzhj 2170 16 the the DT cord-005646-xhx9pzhj 2170 17 airway airway NN cord-005646-xhx9pzhj 2170 18 care care NN cord-005646-xhx9pzhj 2170 19 , , , cord-005646-xhx9pzhj 2170 20 prevention prevention NN cord-005646-xhx9pzhj 2170 21 and and CC cord-005646-xhx9pzhj 2170 22 treatment treatment NN cord-005646-xhx9pzhj 2170 23 of of IN cord-005646-xhx9pzhj 2170 24 aspiration aspiration NN cord-005646-xhx9pzhj 2170 25 pneumonia pneumonia NN cord-005646-xhx9pzhj 2170 26 and and CC cord-005646-xhx9pzhj 2170 27 the the DT cord-005646-xhx9pzhj 2170 28 mechanical mechanical JJ cord-005646-xhx9pzhj 2170 29 ventilation ventilation NN cord-005646-xhx9pzhj 2170 30 if if IN cord-005646-xhx9pzhj 2170 31 respiratory respiratory JJ cord-005646-xhx9pzhj 2170 32 distress distress NN cord-005646-xhx9pzhj 2170 33 presents present NNS cord-005646-xhx9pzhj 2170 34 . . . cord-005646-xhx9pzhj 2171 1 Endotracheal endotracheal JJ cord-005646-xhx9pzhj 2171 2 intubation intubation NN cord-005646-xhx9pzhj 2171 3 should should MD cord-005646-xhx9pzhj 2171 4 be be VB cord-005646-xhx9pzhj 2171 5 performed perform VBN cord-005646-xhx9pzhj 2171 6 whenever whenever WRB cord-005646-xhx9pzhj 2171 7 there there EX cord-005646-xhx9pzhj 2171 8 is be VBZ cord-005646-xhx9pzhj 2171 9 evidence evidence NN cord-005646-xhx9pzhj 2171 10 of of IN cord-005646-xhx9pzhj 2171 11 retention retention NN cord-005646-xhx9pzhj 2171 12 of of IN cord-005646-xhx9pzhj 2171 13 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2171 14 secretions secretion NNS cord-005646-xhx9pzhj 2171 15 , , , cord-005646-xhx9pzhj 2171 16 refractory refractory JJ cord-005646-xhx9pzhj 2171 17 to to IN cord-005646-xhx9pzhj 2171 18 chest chest NN cord-005646-xhx9pzhj 2171 19 physical physical JJ cord-005646-xhx9pzhj 2171 20 therapy therapy NN cord-005646-xhx9pzhj 2171 21 , , , cord-005646-xhx9pzhj 2171 22 weakness weakness NN cord-005646-xhx9pzhj 2171 23 of of IN cord-005646-xhx9pzhj 2171 24 protective protective JJ cord-005646-xhx9pzhj 2171 25 reflexes reflex NNS cord-005646-xhx9pzhj 2171 26 of of IN cord-005646-xhx9pzhj 2171 27 the the DT cord-005646-xhx9pzhj 2171 28 airway airway NN cord-005646-xhx9pzhj 2171 29 , , , cord-005646-xhx9pzhj 2171 30 leading lead VBG cord-005646-xhx9pzhj 2171 31 to to IN cord-005646-xhx9pzhj 2171 32 aspiration aspiration NN cord-005646-xhx9pzhj 2171 33 pneumonia pneumonia NN cord-005646-xhx9pzhj 2171 34 and and CC cord-005646-xhx9pzhj 2171 35 ( ( -LRB- cord-005646-xhx9pzhj 2171 36 or or CC cord-005646-xhx9pzhj 2171 37 ) ) -RRB- cord-005646-xhx9pzhj 2171 38 atelecr atelecr NNP cord-005646-xhx9pzhj 2171 39 ~ ~ NFP cord-005646-xhx9pzhj 2171 40 sis sis NN cord-005646-xhx9pzhj 2171 41 . . . cord-005646-xhx9pzhj 2172 1 Cardiac cardiac JJ cord-005646-xhx9pzhj 2172 2 arrhithmias arrhithmias NN cord-005646-xhx9pzhj 2172 3 too too RB cord-005646-xhx9pzhj 2172 4 , , , cord-005646-xhx9pzhj 2172 5 is be VBZ cord-005646-xhx9pzhj 2172 6 a a DT cord-005646-xhx9pzhj 2172 7 main main JJ cord-005646-xhx9pzhj 2172 8 threat threat NN cord-005646-xhx9pzhj 2172 9 to to IN cord-005646-xhx9pzhj 2172 10 the the DT cord-005646-xhx9pzhj 2172 11 circulatory circulatory JJ cord-005646-xhx9pzhj 2172 12 stability stability NN cord-005646-xhx9pzhj 2172 13 in in IN cord-005646-xhx9pzhj 2172 14 GBS GBS NNP cord-005646-xhx9pzhj 2172 15 . . . cord-005646-xhx9pzhj 2173 1 Therapeutic therapeutic JJ cord-005646-xhx9pzhj 2173 2 plasmapharesis plasmapharesis NN cord-005646-xhx9pzhj 2173 3 has have VBZ cord-005646-xhx9pzhj 2173 4 been be VBN cord-005646-xhx9pzhj 2173 5 shown show VBN cord-005646-xhx9pzhj 2173 6 to to TO cord-005646-xhx9pzhj 2173 7 be be VB cord-005646-xhx9pzhj 2173 8 beneficial beneficial JJ cord-005646-xhx9pzhj 2173 9 , , , cord-005646-xhx9pzhj 2173 10 reducing reduce VBG cord-005646-xhx9pzhj 2173 11 the the DT cord-005646-xhx9pzhj 2173 12 time time NN cord-005646-xhx9pzhj 2173 13 for for IN cord-005646-xhx9pzhj 2173 14 weaning wean VBG cord-005646-xhx9pzhj 2173 15 from from IN cord-005646-xhx9pzhj 2173 16 the the DT cord-005646-xhx9pzhj 2173 17 ventilator ventilator NN cord-005646-xhx9pzhj 2173 18 and and CC cord-005646-xhx9pzhj 2173 19 for for IN cord-005646-xhx9pzhj 2173 20 achieving achieve VBG cord-005646-xhx9pzhj 2173 21 independent independent JJ cord-005646-xhx9pzhj 2173 22 ambulation ambulation NN cord-005646-xhx9pzhj 2173 23 . . . cord-005646-xhx9pzhj 2174 1 However however RB cord-005646-xhx9pzhj 2174 2 , , , cord-005646-xhx9pzhj 2174 3 plasma plasma NN cord-005646-xhx9pzhj 2174 4 exchange exchange NN cord-005646-xhx9pzhj 2174 5 is be VBZ cord-005646-xhx9pzhj 2174 6 expensive expensive JJ cord-005646-xhx9pzhj 2174 7 and and CC cord-005646-xhx9pzhj 2174 8 not not RB cord-005646-xhx9pzhj 2174 9 without without IN cord-005646-xhx9pzhj 2174 10 significant significant JJ cord-005646-xhx9pzhj 2174 11 risks risk NNS cord-005646-xhx9pzhj 2174 12 for for IN cord-005646-xhx9pzhj 2174 13 the the DT cord-005646-xhx9pzhj 2174 14 patient patient NN cord-005646-xhx9pzhj 2174 15 . . . cord-005646-xhx9pzhj 2175 1 Some some DT cord-005646-xhx9pzhj 2175 2 authors author NNS cord-005646-xhx9pzhj 2175 3 find find VBP cord-005646-xhx9pzhj 2175 4 that that IN cord-005646-xhx9pzhj 2175 5 plasmapheresis plasmapheresis NN cord-005646-xhx9pzhj 2175 6 is be VBZ cord-005646-xhx9pzhj 2175 7 not not RB cord-005646-xhx9pzhj 2175 8 effective effective JJ cord-005646-xhx9pzhj 2175 9 for for IN cord-005646-xhx9pzhj 2175 10 patients patient NNS cord-005646-xhx9pzhj 2175 11 with with IN cord-005646-xhx9pzhj 2175 12 fulminant fulminant JJ cord-005646-xhx9pzhj 2175 13 course course NN cord-005646-xhx9pzhj 2175 14 of of IN cord-005646-xhx9pzhj 2175 15 GBS GBS NNP cord-005646-xhx9pzhj 2175 16 and and CC cord-005646-xhx9pzhj 2175 17 blocking blocking NN cord-005646-xhx9pzhj 2175 18 of of IN cord-005646-xhx9pzhj 2175 19 nerve nerve NN cord-005646-xhx9pzhj 2175 20 conduction conduction NN cord-005646-xhx9pzhj 2175 21 . . . cord-005646-xhx9pzhj 2176 1 Recent recent JJ cord-005646-xhx9pzhj 2176 2 studies study NNS cord-005646-xhx9pzhj 2176 3 have have VBP cord-005646-xhx9pzhj 2176 4 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2176 5 that that IN cord-005646-xhx9pzhj 2176 6 intravenous intravenous JJ cord-005646-xhx9pzhj 2176 7 high high JJ cord-005646-xhx9pzhj 2176 8 - - HYPH cord-005646-xhx9pzhj 2176 9 dose dose NN cord-005646-xhx9pzhj 2176 10 immunoglobulin immunoglobulin NN cord-005646-xhx9pzhj 2176 11 can can MD cord-005646-xhx9pzhj 2176 12 be be VB cord-005646-xhx9pzhj 2176 13 equally equally RB cord-005646-xhx9pzhj 2176 14 effective effective JJ cord-005646-xhx9pzhj 2176 15 . . . cord-005646-xhx9pzhj 2177 1 There there EX cord-005646-xhx9pzhj 2177 2 were be VBD cord-005646-xhx9pzhj 2177 3 no no DT cord-005646-xhx9pzhj 2177 4 significant significant JJ cord-005646-xhx9pzhj 2177 5 complications complication NNS cord-005646-xhx9pzhj 2177 6 associated associate VBN cord-005646-xhx9pzhj 2177 7 with with IN cord-005646-xhx9pzhj 2177 8 plasma plasma NN cord-005646-xhx9pzhj 2177 9 exchange exchange NN cord-005646-xhx9pzhj 2177 10 . . . cord-005646-xhx9pzhj 2178 1 All all DT cord-005646-xhx9pzhj 2178 2 presented present VBN cord-005646-xhx9pzhj 2178 3 patients patient NNS cord-005646-xhx9pzhj 2178 4 survived survive VBD cord-005646-xhx9pzhj 2178 5 without without IN cord-005646-xhx9pzhj 2178 6 residual residual JJ cord-005646-xhx9pzhj 2178 7 disability disability NN cord-005646-xhx9pzhj 2178 8 . . . cord-005646-xhx9pzhj 2179 1 Tetraparesis tetraparesis NN cord-005646-xhx9pzhj 2179 2 associated associate VBN cord-005646-xhx9pzhj 2179 3 with with IN cord-005646-xhx9pzhj 2179 4 long long JJ cord-005646-xhx9pzhj 2179 5 - - HYPH cord-005646-xhx9pzhj 2179 6 term term NN cord-005646-xhx9pzhj 2179 7 Paneuronium Paneuronium NNP cord-005646-xhx9pzhj 2179 8 use use NN cord-005646-xhx9pzhj 2179 9 in in IN cord-005646-xhx9pzhj 2179 10 an an DT cord-005646-xhx9pzhj 2179 11 infant infant NN cord-005646-xhx9pzhj 2179 12 . . . cord-005646-xhx9pzhj 2180 1 Paneuronium Paneuronium NNP cord-005646-xhx9pzhj 2180 2 is be VBZ cord-005646-xhx9pzhj 2180 3 a a DT cord-005646-xhx9pzhj 2180 4 muscle muscle NN cord-005646-xhx9pzhj 2180 5 relaxant relaxant NN cord-005646-xhx9pzhj 2180 6 used use VBN cord-005646-xhx9pzhj 2180 7 in in IN cord-005646-xhx9pzhj 2180 8 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2180 9 management management NN cord-005646-xhx9pzhj 2180 10 of of IN cord-005646-xhx9pzhj 2180 11 patients patient NNS cord-005646-xhx9pzhj 2180 12 with with IN cord-005646-xhx9pzhj 2180 13 respiratory respiratory JJ cord-005646-xhx9pzhj 2180 14 distress distress NN cord-005646-xhx9pzhj 2180 15 in in IN cord-005646-xhx9pzhj 2180 16 intensive intensive JJ cord-005646-xhx9pzhj 2180 17 care care NN cord-005646-xhx9pzhj 2180 18 unit unit NN cord-005646-xhx9pzhj 2180 19 . . . cord-005646-xhx9pzhj 2181 1 After after IN cord-005646-xhx9pzhj 2181 2 the the DT cord-005646-xhx9pzhj 2181 3 end end NN cord-005646-xhx9pzhj 2181 4 of of IN cord-005646-xhx9pzhj 2181 5 sedation sedation NN cord-005646-xhx9pzhj 2181 6 some some DT cord-005646-xhx9pzhj 2181 7 patients patient NNS cord-005646-xhx9pzhj 2181 8 were be VBD cord-005646-xhx9pzhj 2181 9 found find VBN cord-005646-xhx9pzhj 2181 10 to to TO cord-005646-xhx9pzhj 2181 11 have have VB cord-005646-xhx9pzhj 2181 12 severe severe JJ cord-005646-xhx9pzhj 2181 13 tetraparesis tetraparesis NN cord-005646-xhx9pzhj 2181 14 . . . cord-005646-xhx9pzhj 2182 1 Paresis Paresis NNP cord-005646-xhx9pzhj 2182 2 was be VBD cord-005646-xhx9pzhj 2182 3 accompanied accompany VBN cord-005646-xhx9pzhj 2182 4 by by IN cord-005646-xhx9pzhj 2182 5 complete complete JJ cord-005646-xhx9pzhj 2182 6 areflexia areflexia NN cord-005646-xhx9pzhj 2182 7 and and CC cord-005646-xhx9pzhj 2182 8 diffuse diffuse JJ cord-005646-xhx9pzhj 2182 9 atrophy atrophy NN cord-005646-xhx9pzhj 2182 10 of of IN cord-005646-xhx9pzhj 2182 11 alt alt JJ cord-005646-xhx9pzhj 2182 12 extremity extremity NN cord-005646-xhx9pzhj 2182 13 muscles muscle NNS cord-005646-xhx9pzhj 2182 14 . . . cord-005646-xhx9pzhj 2183 1 This this DT cord-005646-xhx9pzhj 2183 2 neuromuscular neuromuscular JJ cord-005646-xhx9pzhj 2183 3 complication complication NN cord-005646-xhx9pzhj 2183 4 is be VBZ cord-005646-xhx9pzhj 2183 5 caused cause VBN cord-005646-xhx9pzhj 2183 6 by by IN cord-005646-xhx9pzhj 2183 7 prolonged prolong VBN cord-005646-xhx9pzhj 2183 8 high high JJ cord-005646-xhx9pzhj 2183 9 - - HYPH cord-005646-xhx9pzhj 2183 10 dosage dosage NN cord-005646-xhx9pzhj 2183 11 pancuronium pancuronium NN cord-005646-xhx9pzhj 2183 12 treatment treatment NN cord-005646-xhx9pzhj 2183 13 . . . cord-005646-xhx9pzhj 2184 1 In in IN cord-005646-xhx9pzhj 2184 2 the the DT cord-005646-xhx9pzhj 2184 3 last last JJ cord-005646-xhx9pzhj 2184 4 5 5 CD cord-005646-xhx9pzhj 2184 5 years year NNS cord-005646-xhx9pzhj 2184 6 , , , cord-005646-xhx9pzhj 2184 7 numerous numerous JJ cord-005646-xhx9pzhj 2184 8 reports report NNS cord-005646-xhx9pzhj 2184 9 have have VBP cord-005646-xhx9pzhj 2184 10 linked link VBN cord-005646-xhx9pzhj 2184 11 the the DT cord-005646-xhx9pzhj 2184 12 use use NN cord-005646-xhx9pzhj 2184 13 of of IN cord-005646-xhx9pzhj 2184 14 pancuronium pancuronium NN cord-005646-xhx9pzhj 2184 15 bromide bromide NN cord-005646-xhx9pzhj 2184 16 with with IN cord-005646-xhx9pzhj 2184 17 prolonged prolong VBN cord-005646-xhx9pzhj 2184 18 paralysis paralysis NN cord-005646-xhx9pzhj 2184 19 , , , cord-005646-xhx9pzhj 2184 20 disuse disuse NN cord-005646-xhx9pzhj 2184 21 atrophy atrophy NN cord-005646-xhx9pzhj 2184 22 and and CC cord-005646-xhx9pzhj 2184 23 areflexia areflexia NN cord-005646-xhx9pzhj 2184 24 . . . cord-005646-xhx9pzhj 2185 1 This this DT cord-005646-xhx9pzhj 2185 2 side side NN cord-005646-xhx9pzhj 2185 3 - - HYPH cord-005646-xhx9pzhj 2185 4 effect effect NN cord-005646-xhx9pzhj 2185 5 is be VBZ cord-005646-xhx9pzhj 2185 6 well well RB cord-005646-xhx9pzhj 2185 7 known know VBN cord-005646-xhx9pzhj 2185 8 in in IN cord-005646-xhx9pzhj 2185 9 adults adult NNS cord-005646-xhx9pzhj 2185 10 patients patient NNS cord-005646-xhx9pzhj 2185 11 but but CC cord-005646-xhx9pzhj 2185 12 rare rare JJ cord-005646-xhx9pzhj 2185 13 in in IN cord-005646-xhx9pzhj 2185 14 a a DT cord-005646-xhx9pzhj 2185 15 pediatric pediatric JJ cord-005646-xhx9pzhj 2185 16 intensive intensive JJ cord-005646-xhx9pzhj 2185 17 care care NN cord-005646-xhx9pzhj 2185 18 unit unit NN cord-005646-xhx9pzhj 2185 19 . . . cord-005646-xhx9pzhj 2186 1 We -PRON- PRP cord-005646-xhx9pzhj 2186 2 describe describe VBP cord-005646-xhx9pzhj 2186 3 one one CD cord-005646-xhx9pzhj 2186 4 pediatric pediatric JJ cord-005646-xhx9pzhj 2186 5 observation observation NN cord-005646-xhx9pzhj 2186 6 of of IN cord-005646-xhx9pzhj 2186 7 tetraparesis tetraparesis NN cord-005646-xhx9pzhj 2186 8 after after IN cord-005646-xhx9pzhj 2186 9 prolonged prolong VBN cord-005646-xhx9pzhj 2186 10 pancuronium pancuronium NN cord-005646-xhx9pzhj 2186 11 treatment treatment NN cord-005646-xhx9pzhj 2186 12 in in IN cord-005646-xhx9pzhj 2186 13 a a DT cord-005646-xhx9pzhj 2186 14 9-month 9-month JJ cord-005646-xhx9pzhj 2186 15 - - HYPH cord-005646-xhx9pzhj 2186 16 old old JJ cord-005646-xhx9pzhj 2186 17 girl girl NN cord-005646-xhx9pzhj 2186 18 , , , cord-005646-xhx9pzhj 2186 19 This this DT cord-005646-xhx9pzhj 2186 20 female female JJ cord-005646-xhx9pzhj 2186 21 infant infant NN cord-005646-xhx9pzhj 2186 22 developed develop VBD cord-005646-xhx9pzhj 2186 23 respiratory respiratory JJ cord-005646-xhx9pzhj 2186 24 distress distress NN cord-005646-xhx9pzhj 2186 25 syndrome syndrome NN cord-005646-xhx9pzhj 2186 26 and and CC cord-005646-xhx9pzhj 2186 27 was be VBD cord-005646-xhx9pzhj 2186 28 intubated intubate VBN cord-005646-xhx9pzhj 2186 29 and and CC cord-005646-xhx9pzhj 2186 30 mechanically mechanically RB cord-005646-xhx9pzhj 2186 31 ventilated ventilate VBN cord-005646-xhx9pzhj 2186 32 . . . cord-005646-xhx9pzhj 2187 1 To to TO cord-005646-xhx9pzhj 2187 2 decrease decrease VB cord-005646-xhx9pzhj 2187 3 chest chest NN cord-005646-xhx9pzhj 2187 4 wall wall NN cord-005646-xhx9pzhj 2187 5 rigidity rigidity NN cord-005646-xhx9pzhj 2187 6 pancuronium pancuronium VBZ cord-005646-xhx9pzhj 2187 7 bromide bromide NN cord-005646-xhx9pzhj 2187 8 was be VBD cord-005646-xhx9pzhj 2187 9 administered administer VBN cord-005646-xhx9pzhj 2187 10 during during IN cord-005646-xhx9pzhj 2187 11 11 11 CD cord-005646-xhx9pzhj 2187 12 days day NNS cord-005646-xhx9pzhj 2187 13 . . . cord-005646-xhx9pzhj 2188 1 ( ( -LRB- cord-005646-xhx9pzhj 2188 2 she -PRON- PRP cord-005646-xhx9pzhj 2188 3 received receive VBD cord-005646-xhx9pzhj 2188 4 approximately approximately RB cord-005646-xhx9pzhj 2188 5 120 120 CD cord-005646-xhx9pzhj 2188 6 mg mg NNS cord-005646-xhx9pzhj 2188 7 of of IN cord-005646-xhx9pzhj 2188 8 pancuronium pancuronium NN cord-005646-xhx9pzhj 2188 9 bromide bromide NN cord-005646-xhx9pzhj 2188 10 ) ) -RRB- cord-005646-xhx9pzhj 2188 11 . . . cord-005646-xhx9pzhj 2189 1 On on IN cord-005646-xhx9pzhj 2189 2 day day NN cord-005646-xhx9pzhj 2189 3 12 12 CD cord-005646-xhx9pzhj 2189 4 the the DT cord-005646-xhx9pzhj 2189 5 drug drug NN cord-005646-xhx9pzhj 2189 6 was be VBD cord-005646-xhx9pzhj 2189 7 discontinued discontinue VBN cord-005646-xhx9pzhj 2189 8 and and CC cord-005646-xhx9pzhj 2189 9 the the DT cord-005646-xhx9pzhj 2189 10 patient patient NN cord-005646-xhx9pzhj 2189 11 had have VBD cord-005646-xhx9pzhj 2189 12 severe severe JJ cord-005646-xhx9pzhj 2189 13 tetraplegia tetraplegia NNP cord-005646-xhx9pzhj 2189 14 and and CC cord-005646-xhx9pzhj 2189 15 areflexia areflexia NNP cord-005646-xhx9pzhj 2189 16 with with IN cord-005646-xhx9pzhj 2189 17 normal normal JJ cord-005646-xhx9pzhj 2189 18 head head NN cord-005646-xhx9pzhj 2189 19 movements movement NNS cord-005646-xhx9pzhj 2189 20 . . . cord-005646-xhx9pzhj 2190 1 Electromyograpliy Electromyograpliy NNP cord-005646-xhx9pzhj 2190 2 showed show VBD cord-005646-xhx9pzhj 2190 3 absence absence NN cord-005646-xhx9pzhj 2190 4 of of IN cord-005646-xhx9pzhj 2190 5 any any DT cord-005646-xhx9pzhj 2190 6 disorder disorder NN cord-005646-xhx9pzhj 2190 7 of of IN cord-005646-xhx9pzhj 2190 8 neuromuscular neuromuscular JJ cord-005646-xhx9pzhj 2190 9 transmission transmission NN cord-005646-xhx9pzhj 2190 10 . . . cord-005646-xhx9pzhj 2191 1 This this DT cord-005646-xhx9pzhj 2191 2 infant infant NN cord-005646-xhx9pzhj 2191 3 showed show VBD cord-005646-xhx9pzhj 2191 4 a a DT cord-005646-xhx9pzhj 2191 5 recoveLy recovely NN cord-005646-xhx9pzhj 2191 6 of of IN cord-005646-xhx9pzhj 2191 7 muscles muscle NNS cord-005646-xhx9pzhj 2191 8 after after IN cord-005646-xhx9pzhj 2191 9 3 3 CD cord-005646-xhx9pzhj 2191 10 months month NNS cord-005646-xhx9pzhj 2191 11 . . . cord-005646-xhx9pzhj 2192 1 The the DT cord-005646-xhx9pzhj 2192 2 other other JJ cord-005646-xhx9pzhj 2192 3 causes cause NNS cord-005646-xhx9pzhj 2192 4 of of IN cord-005646-xhx9pzhj 2192 5 peripheral peripheral JJ cord-005646-xhx9pzhj 2192 6 neuropathies neuropathy NNS cord-005646-xhx9pzhj 2192 7 were be VBD cord-005646-xhx9pzhj 2192 8 eliminated eliminate VBN cord-005646-xhx9pzhj 2192 9 . . . cord-005646-xhx9pzhj 2193 1 Electroencephalograms Electroencephalograms NNP cord-005646-xhx9pzhj 2193 2 and and CC cord-005646-xhx9pzhj 2193 3 head head NN cord-005646-xhx9pzhj 2193 4 scans scan NNS cord-005646-xhx9pzhj 2193 5 were be VBD cord-005646-xhx9pzhj 2193 6 normal normal JJ cord-005646-xhx9pzhj 2193 7 . . . cord-005646-xhx9pzhj 2194 1 The the DT cord-005646-xhx9pzhj 2194 2 recovery recovery NN cord-005646-xhx9pzhj 2194 3 pattern pattern NN cord-005646-xhx9pzhj 2194 4 observed observe VBN cord-005646-xhx9pzhj 2194 5 in in IN cord-005646-xhx9pzhj 2194 6 our -PRON- PRP$ cord-005646-xhx9pzhj 2194 7 patient patient NN cord-005646-xhx9pzhj 2194 8 correspond correspond VB cord-005646-xhx9pzhj 2194 9 to to IN cord-005646-xhx9pzhj 2194 10 the the DT cord-005646-xhx9pzhj 2194 11 process process NN cord-005646-xhx9pzhj 2194 12 of of IN cord-005646-xhx9pzhj 2194 13 regeneration regeneration NN cord-005646-xhx9pzhj 2194 14 after after IN cord-005646-xhx9pzhj 2194 15 axonal axonal JJ cord-005646-xhx9pzhj 2194 16 degeneration degeneration NN cord-005646-xhx9pzhj 2194 17 . . . cord-005646-xhx9pzhj 2195 1 It -PRON- PRP cord-005646-xhx9pzhj 2195 2 is be VBZ cord-005646-xhx9pzhj 2195 3 suggested suggest VBN cord-005646-xhx9pzhj 2195 4 that that IN cord-005646-xhx9pzhj 2195 5 these these DT cord-005646-xhx9pzhj 2195 6 neuromuscular neuromuscular JJ cord-005646-xhx9pzhj 2195 7 complications complication NNS cord-005646-xhx9pzhj 2195 8 were be VBD cord-005646-xhx9pzhj 2195 9 caused cause VBN cord-005646-xhx9pzhj 2195 10 by by IN cord-005646-xhx9pzhj 2195 11 prolonged prolong VBN cord-005646-xhx9pzhj 2195 12 high high JJ cord-005646-xhx9pzhj 2195 13 - - HYPH cord-005646-xhx9pzhj 2195 14 dosage dosage NN cord-005646-xhx9pzhj 2195 15 pancuronium pancuronium NN cord-005646-xhx9pzhj 2195 16 treatment treatment NN cord-005646-xhx9pzhj 2195 17 ( ( -LRB- cord-005646-xhx9pzhj 2195 18 associated associate VBN cord-005646-xhx9pzhj 2195 19 with with IN cord-005646-xhx9pzhj 2195 20 cortieoid cortieoid NNP cord-005646-xhx9pzhj 2195 21 and and CC cord-005646-xhx9pzhj 2195 22 aminoglucosides aminoglucosides NNP cord-005646-xhx9pzhj 2195 23 ) ) -RRB- cord-005646-xhx9pzhj 2195 24 . . . cord-005646-xhx9pzhj 2195 25 _SP cord-005646-xhx9pzhj 2196 1 Polyneuropathy Polyneuropathy NNP cord-005646-xhx9pzhj 2196 2 syndrome syndrome NN cord-005646-xhx9pzhj 2196 3 in in IN cord-005646-xhx9pzhj 2196 4 adult adult NN cord-005646-xhx9pzhj 2196 5 LC.U. LC.U. NNP cord-005646-xhx9pzhj 2196 6 appeared appear VBD cord-005646-xhx9pzhj 2196 7 in in IN cord-005646-xhx9pzhj 2196 8 literature literature NN cord-005646-xhx9pzhj 2196 9 in in IN cord-005646-xhx9pzhj 2196 10 1984 1984 CD cord-005646-xhx9pzhj 2196 11 and and CC cord-005646-xhx9pzhj 2196 12 is be VBZ cord-005646-xhx9pzhj 2196 13 extremely extremely RB cord-005646-xhx9pzhj 2196 14 common common JJ cord-005646-xhx9pzhj 2196 15 in in IN cord-005646-xhx9pzhj 2196 16 long long JJ cord-005646-xhx9pzhj 2196 17 stay stay NN cord-005646-xhx9pzhj 2196 18 cases case NNS cord-005646-xhx9pzhj 2196 19 . . . cord-005646-xhx9pzhj 2197 1 The the DT cord-005646-xhx9pzhj 2197 2 etiology etiology NN cord-005646-xhx9pzhj 2197 3 of of IN cord-005646-xhx9pzhj 2197 4 these these DT cord-005646-xhx9pzhj 2197 5 disorders disorder NNS cord-005646-xhx9pzhj 2197 6 remains remain VBZ cord-005646-xhx9pzhj 2197 7 elusive elusive JJ cord-005646-xhx9pzhj 2197 8 . . . cord-005646-xhx9pzhj 2198 1 It -PRON- PRP cord-005646-xhx9pzhj 2198 2 is be VBZ cord-005646-xhx9pzhj 2198 3 tempting tempt VBG cord-005646-xhx9pzhj 2198 4 to to TO cord-005646-xhx9pzhj 2198 5 ascribe ascribe VB cord-005646-xhx9pzhj 2198 6 them -PRON- PRP cord-005646-xhx9pzhj 2198 7 to to IN cord-005646-xhx9pzhj 2198 8 administration administration NN cord-005646-xhx9pzhj 2198 9 of of IN cord-005646-xhx9pzhj 2198 10 drugs drug NNS cord-005646-xhx9pzhj 2198 11 ( ( -LRB- cord-005646-xhx9pzhj 2198 12 muscle muscle NN cord-005646-xhx9pzhj 2198 13 relaxants relaxant NNS cord-005646-xhx9pzhj 2198 14 , , , cord-005646-xhx9pzhj 2198 15 steroids steroid NNS cord-005646-xhx9pzhj 2198 16 , , , cord-005646-xhx9pzhj 2198 17 aminoglycosidea aminoglycosidea NNP cord-005646-xhx9pzhj 2198 18 ) ) -RRB- cord-005646-xhx9pzhj 2198 19 , , , cord-005646-xhx9pzhj 2198 20 plolonged plolonge VBN cord-005646-xhx9pzhj 2198 21 immobility immobility NN cord-005646-xhx9pzhj 2198 22 , , , cord-005646-xhx9pzhj 2198 23 malutrition malutrition NN cord-005646-xhx9pzhj 2198 24 , , , cord-005646-xhx9pzhj 2198 25 sepsis sepsis NN cord-005646-xhx9pzhj 2198 26 and and CC cord-005646-xhx9pzhj 2198 27 ischemia ischemia NN cord-005646-xhx9pzhj 2198 28 associated associate VBN cord-005646-xhx9pzhj 2198 29 with with IN cord-005646-xhx9pzhj 2198 30 reperfusion reperfusion NN cord-005646-xhx9pzhj 2198 31 injury injury NN cord-005646-xhx9pzhj 2198 32 . . . cord-005646-xhx9pzhj 2199 1 To to IN cord-005646-xhx9pzhj 2199 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2199 3 knowledge knowledge NN cord-005646-xhx9pzhj 2199 4 there there EX cord-005646-xhx9pzhj 2199 5 is be VBZ cord-005646-xhx9pzhj 2199 6 only only RB cord-005646-xhx9pzhj 2199 7 one one CD cord-005646-xhx9pzhj 2199 8 case case NN cord-005646-xhx9pzhj 2199 9 report report NN cord-005646-xhx9pzhj 2199 10 of of IN cord-005646-xhx9pzhj 2199 11 similar similar JJ cord-005646-xhx9pzhj 2199 12 condition condition NN cord-005646-xhx9pzhj 2199 13 in in IN cord-005646-xhx9pzhj 2199 14 a a DT cord-005646-xhx9pzhj 2199 15 children child NNS cord-005646-xhx9pzhj 2199 16 I.C.U. i.c.u. NN cord-005646-xhx9pzhj 2199 17 ( ( -LRB- cord-005646-xhx9pzhj 2199 18 Pascucci Pascucci NNP cord-005646-xhx9pzhj 2199 19 1990 1990 CD cord-005646-xhx9pzhj 2199 20 ) ) -RRB- cord-005646-xhx9pzhj 2200 1 We -PRON- PRP cord-005646-xhx9pzhj 2200 2 present present VBP cord-005646-xhx9pzhj 2200 3 a a DT cord-005646-xhx9pzhj 2200 4 serie serie NN cord-005646-xhx9pzhj 2200 5 of of IN cord-005646-xhx9pzhj 2200 6 16 16 CD cord-005646-xhx9pzhj 2200 7 previously previously RB cord-005646-xhx9pzhj 2200 8 healthy healthy JJ cord-005646-xhx9pzhj 2200 9 children child NNS cord-005646-xhx9pzhj 2200 10 , , , cord-005646-xhx9pzhj 2200 11 aged age VBN cord-005646-xhx9pzhj 2200 12 9 9 CD cord-005646-xhx9pzhj 2200 13 months month NNS cord-005646-xhx9pzhj 2200 14 to to IN cord-005646-xhx9pzhj 2200 15 13 13 CD cord-005646-xhx9pzhj 2200 16 years year NNS cord-005646-xhx9pzhj 2200 17 , , , cord-005646-xhx9pzhj 2200 18 who who WP cord-005646-xhx9pzhj 2200 19 admitted admit VBD cord-005646-xhx9pzhj 2200 20 in in IN cord-005646-xhx9pzhj 2200 21 I.C.U I.C.U NNP cord-005646-xhx9pzhj 2200 22 with with IN cord-005646-xhx9pzhj 2200 23 respiratory respiratory JJ cord-005646-xhx9pzhj 2200 24 failure failure NN cord-005646-xhx9pzhj 2200 25 and and CC cord-005646-xhx9pzhj 2200 26 who who WP cord-005646-xhx9pzhj 2200 27 following follow VBG cord-005646-xhx9pzhj 2200 28 weaning wean VBG cord-005646-xhx9pzhj 2200 29 from from IN cord-005646-xhx9pzhj 2200 30 M.V M.V NNP cord-005646-xhx9pzhj 2200 31 , , , cord-005646-xhx9pzhj 2200 32 remained remain VBD cord-005646-xhx9pzhj 2200 33 in in IN cord-005646-xhx9pzhj 2200 34 profound profound JJ cord-005646-xhx9pzhj 2200 35 diffuse diffuse JJ cord-005646-xhx9pzhj 2200 36 hypotonia hypotonia NNS cord-005646-xhx9pzhj 2200 37 with with IN cord-005646-xhx9pzhj 2200 38 proximal proximal JJ cord-005646-xhx9pzhj 2200 39 and and CC cord-005646-xhx9pzhj 2200 40 distal distal JJ cord-005646-xhx9pzhj 2200 41 muscle muscle NN cord-005646-xhx9pzhj 2200 42 weakness weakness NN cord-005646-xhx9pzhj 2200 43 for for IN cord-005646-xhx9pzhj 2200 44 various various JJ cord-005646-xhx9pzhj 2200 45 length length NN cord-005646-xhx9pzhj 2200 46 of of IN cord-005646-xhx9pzhj 2200 47 time time NN cord-005646-xhx9pzhj 2200 48 , , , cord-005646-xhx9pzhj 2200 49 Recovery recovery NN cord-005646-xhx9pzhj 2200 50 of of IN cord-005646-xhx9pzhj 2200 51 muscle muscle NN cord-005646-xhx9pzhj 2200 52 strength strength NN cord-005646-xhx9pzhj 2200 53 occured occur VBD cord-005646-xhx9pzhj 2200 54 in in IN cord-005646-xhx9pzhj 2200 55 a a DT cord-005646-xhx9pzhj 2200 56 week week NN cord-005646-xhx9pzhj 2200 57 or or CC cord-005646-xhx9pzhj 2200 58 months month NNS cord-005646-xhx9pzhj 2200 59 { { -LRB- cord-005646-xhx9pzhj 2200 60 the the DT cord-005646-xhx9pzhj 2200 61 longest long JJS cord-005646-xhx9pzhj 2200 62 I0 i0 NN cord-005646-xhx9pzhj 2200 63 months month NNS cord-005646-xhx9pzhj 2200 64 ) ) -RRB- cord-005646-xhx9pzhj 2200 65 , , , cord-005646-xhx9pzhj 2200 66 All all DT cord-005646-xhx9pzhj 2200 67 children child NNS cord-005646-xhx9pzhj 2200 68 , , , cord-005646-xhx9pzhj 2200 69 except except IN cord-005646-xhx9pzhj 2200 70 one one CD cord-005646-xhx9pzhj 2200 71 , , , cord-005646-xhx9pzhj 2200 72 3 3 CD cord-005646-xhx9pzhj 2200 73 - - SYM cord-005646-xhx9pzhj 2200 74 4 4 CD cord-005646-xhx9pzhj 2200 75 days day NNS cord-005646-xhx9pzhj 2200 76 before before IN cord-005646-xhx9pzhj 2200 77 admission admission NN cord-005646-xhx9pzhj 2200 78 developed develop VBD cord-005646-xhx9pzhj 2200 79 symptoms symptom NNS cord-005646-xhx9pzhj 2200 80 of of IN cord-005646-xhx9pzhj 2200 81 either either CC cord-005646-xhx9pzhj 2200 82 respiratory respiratory JJ cord-005646-xhx9pzhj 2200 83 or or CC cord-005646-xhx9pzhj 2200 84 upper upper JJ cord-005646-xhx9pzhj 2200 85 airway airway NN cord-005646-xhx9pzhj 2200 86 infection infection NN cord-005646-xhx9pzhj 2200 87 with with IN cord-005646-xhx9pzhj 2200 88 fever fever NN cord-005646-xhx9pzhj 2200 89 . . . cord-005646-xhx9pzhj 2201 1 On on IN cord-005646-xhx9pzhj 2201 2 admission admission NN cord-005646-xhx9pzhj 2201 3 viral viral JJ cord-005646-xhx9pzhj 2201 4 and and CC cord-005646-xhx9pzhj 2201 5 bacterial bacterial JJ cord-005646-xhx9pzhj 2201 6 cultures culture NNS cord-005646-xhx9pzhj 2201 7 were be VBD cord-005646-xhx9pzhj 2201 8 positive positive JJ cord-005646-xhx9pzhj 2201 9 in in IN cord-005646-xhx9pzhj 2201 10 2 2 CD cord-005646-xhx9pzhj 2201 11 cases case NNS cord-005646-xhx9pzhj 2201 12 ( ( -LRB- cord-005646-xhx9pzhj 2201 13 Haemophilus haemophilus JJ cord-005646-xhx9pzhj 2201 14 influenze influenze NN cord-005646-xhx9pzhj 2201 15 , , , cord-005646-xhx9pzhj 2201 16 Herpes Herpes NNP cord-005646-xhx9pzhj 2201 17 virus virus NN cord-005646-xhx9pzhj 2201 18 ) ) -RRB- cord-005646-xhx9pzhj 2201 19 . . . cord-005646-xhx9pzhj 2202 1 During during IN cord-005646-xhx9pzhj 2202 2 treatment treatment NN cord-005646-xhx9pzhj 2202 3 9 9 CD cord-005646-xhx9pzhj 2202 4 patients patient NNS cord-005646-xhx9pzhj 2202 5 became become VBD cord-005646-xhx9pzhj 2202 6 septic septic JJ cord-005646-xhx9pzhj 2202 7 . . . cord-005646-xhx9pzhj 2203 1 Muscle muscle NN cord-005646-xhx9pzhj 2203 2 histological histological JJ cord-005646-xhx9pzhj 2203 3 and and CC cord-005646-xhx9pzhj 2203 4 Neurophusiological Neurophusiological NNP cord-005646-xhx9pzhj 2203 5 investigations investigation NNS cord-005646-xhx9pzhj 2203 6 have have VBP cord-005646-xhx9pzhj 2203 7 not not RB cord-005646-xhx9pzhj 2203 8 been be VBN cord-005646-xhx9pzhj 2203 9 done do VBN cord-005646-xhx9pzhj 2203 10 . . . cord-005646-xhx9pzhj 2204 1 Considering consider VBG cord-005646-xhx9pzhj 2204 2 the the DT cord-005646-xhx9pzhj 2204 3 multifactorial multifactorial JJ cord-005646-xhx9pzhj 2204 4 nature nature NN cord-005646-xhx9pzhj 2204 5 of of IN cord-005646-xhx9pzhj 2204 6 the the DT cord-005646-xhx9pzhj 2204 7 aquired aquire VBN cord-005646-xhx9pzhj 2204 8 NMD NMD NNP cord-005646-xhx9pzhj 2204 9 in in IN cord-005646-xhx9pzhj 2204 10 adult adult NN cord-005646-xhx9pzhj 2204 11 critically critically RB cord-005646-xhx9pzhj 2204 12 ill ill JJ cord-005646-xhx9pzhj 2204 13 pts pts NN cord-005646-xhx9pzhj 2204 14 , , , cord-005646-xhx9pzhj 2204 15 is be VBZ cord-005646-xhx9pzhj 2204 16 impossible impossible JJ cord-005646-xhx9pzhj 2204 17 to to TO cord-005646-xhx9pzhj 2204 18 attribute attribute VB cord-005646-xhx9pzhj 2204 19 the the DT cord-005646-xhx9pzhj 2204 20 muscle muscle NN cord-005646-xhx9pzhj 2204 21 weakness weakness NN cord-005646-xhx9pzhj 2204 22 of of IN cord-005646-xhx9pzhj 2204 23 our -PRON- PRP$ cord-005646-xhx9pzhj 2204 24 pts pt NNS cord-005646-xhx9pzhj 2204 25 to to IN cord-005646-xhx9pzhj 2204 26 any any DT cord-005646-xhx9pzhj 2204 27 specific specific JJ cord-005646-xhx9pzhj 2204 28 cause cause NN cord-005646-xhx9pzhj 2204 29 , , . cord-005646-xhx9pzhj 2205 1 In in IN cord-005646-xhx9pzhj 2205 2 conclusion conclusion NN cord-005646-xhx9pzhj 2205 3 , , , cord-005646-xhx9pzhj 2205 4 our -PRON- PRP$ cord-005646-xhx9pzhj 2205 5 findings finding NNS cord-005646-xhx9pzhj 2205 6 suggest suggest VBP cord-005646-xhx9pzhj 2205 7 the the DT cord-005646-xhx9pzhj 2205 8 need need NN cord-005646-xhx9pzhj 2205 9 for for IN cord-005646-xhx9pzhj 2205 10 further further JJ cord-005646-xhx9pzhj 2205 11 investigation investigation NN cord-005646-xhx9pzhj 2205 12 of of IN cord-005646-xhx9pzhj 2205 13 NMD NMD NNP cord-005646-xhx9pzhj 2205 14 in in IN cord-005646-xhx9pzhj 2205 15 critically critically RB cord-005646-xhx9pzhj 2205 16 ill ill JJ cord-005646-xhx9pzhj 2205 17 children child NNS cord-005646-xhx9pzhj 2205 18 treated treat VBN cord-005646-xhx9pzhj 2205 19 in in IN cord-005646-xhx9pzhj 2205 20 I.C.U. I.C.U. NNP cord-005646-xhx9pzhj 2205 21 A A NNP cord-005646-xhx9pzhj 2205 22 van van NNP cord-005646-xhx9pzhj 2205 23 Esch Esch NNP cord-005646-xhx9pzhj 2205 24 , , , cord-005646-xhx9pzhj 2205 25 HA HA NNP cord-005646-xhx9pzhj 2205 26 van van NNP cord-005646-xhx9pzhj 2205 27 Steen Steen NNP cord-005646-xhx9pzhj 2205 28 ~ ~ NNP cord-005646-xhx9pzhj 2205 29 l l NNP cord-005646-xhx9pzhj 2205 30 - - HYPH cord-005646-xhx9pzhj 2205 31 M011 M011 NNP cord-005646-xhx9pzhj 2205 32 , , , cord-005646-xhx9pzhj 2205 33 IR IR NNP cord-005646-xhx9pzhj 2205 34 Ramtal Ramtal NNP cord-005646-xhx9pzhj 2205 35 , , , cord-005646-xhx9pzhj 2205 36 G G NNP cord-005646-xhx9pzhj 2205 37 Derksen Derksen NNP cord-005646-xhx9pzhj 2205 38 - - HYPH cord-005646-xhx9pzhj 2205 39 Lubsen Lubsen NNP cord-005646-xhx9pzhj 2205 40 , , , cord-005646-xhx9pzhj 2205 41 IDF IDF NNP cord-005646-xhx9pzhj 2205 42 Habbema Habbema NNP cord-005646-xhx9pzhj 2205 43 . . . cord-005646-xhx9pzhj 2206 1 Febrile febrile JJ cord-005646-xhx9pzhj 2206 2 Status status NN cord-005646-xhx9pzhj 2206 3 Epilepticus epilepticus NN cord-005646-xhx9pzhj 2206 4 ( ( -LRB- cord-005646-xhx9pzhj 2206 5 FSE FSE NNP cord-005646-xhx9pzhj 2206 6 ) ) -RRB- cord-005646-xhx9pzhj 2206 7 is be VBZ cord-005646-xhx9pzhj 2206 8 a a DT cord-005646-xhx9pzhj 2206 9 prolonged prolonged JJ cord-005646-xhx9pzhj 2206 10 and and CC cord-005646-xhx9pzhj 2206 11 serious serious JJ cord-005646-xhx9pzhj 2206 12 febrile febrile JJ cord-005646-xhx9pzhj 2206 13 seizure seizure NN cord-005646-xhx9pzhj 2206 14 . . . cord-005646-xhx9pzhj 2207 1 Little little JJ cord-005646-xhx9pzhj 2207 2 is be VBZ cord-005646-xhx9pzhj 2207 3 known know VBN cord-005646-xhx9pzhj 2207 4 about about IN cord-005646-xhx9pzhj 2207 5 the the DT cord-005646-xhx9pzhj 2207 6 outcome outcome NN cord-005646-xhx9pzhj 2207 7 of of IN cord-005646-xhx9pzhj 2207 8 FSE FSE NNP cord-005646-xhx9pzhj 2207 9 in in IN cord-005646-xhx9pzhj 2207 10 neurologically neurologically RB cord-005646-xhx9pzhj 2207 11 normal normal JJ cord-005646-xhx9pzhj 2207 12 children child NNS cord-005646-xhx9pzhj 2207 13 . . . cord-005646-xhx9pzhj 2208 1 This this DT cord-005646-xhx9pzhj 2208 2 survey survey NN cord-005646-xhx9pzhj 2208 3 involved involve VBD cord-005646-xhx9pzhj 2208 4 patients patient NNS cord-005646-xhx9pzhj 2208 5 between between IN cord-005646-xhx9pzhj 2208 6 6 6 CD cord-005646-xhx9pzhj 2208 7 months month NNS cord-005646-xhx9pzhj 2208 8 and and CC cord-005646-xhx9pzhj 2208 9 6 6 CD cord-005646-xhx9pzhj 2208 10 years year NNS cord-005646-xhx9pzhj 2208 11 of of IN cord-005646-xhx9pzhj 2208 12 age age NN cord-005646-xhx9pzhj 2208 13 who who WP cord-005646-xhx9pzhj 2208 14 had have VBD cord-005646-xhx9pzhj 2208 15 visited visit VBN cord-005646-xhx9pzhj 2208 16 due due IN cord-005646-xhx9pzhj 2208 17 to to IN cord-005646-xhx9pzhj 2208 18 their -PRON- PRP$ cord-005646-xhx9pzhj 2208 19 first first JJ cord-005646-xhx9pzhj 2208 20 FSE FSE NNP cord-005646-xhx9pzhj 2208 21 , , , cord-005646-xhx9pzhj 2208 22 the the DT cord-005646-xhx9pzhj 2208 23 Sophia Sophia NNP cord-005646-xhx9pzhj 2208 24 Children Children NNPS cord-005646-xhx9pzhj 2208 25 's 's POS cord-005646-xhx9pzhj 2208 26 Hospital Hospital NNP cord-005646-xhx9pzhj 2208 27 during during IN cord-005646-xhx9pzhj 2208 28 the the DT cord-005646-xhx9pzhj 2208 29 period period NN cord-005646-xhx9pzhj 2208 30 of of IN cord-005646-xhx9pzhj 2208 31 january january NNP cord-005646-xhx9pzhj 2208 32 1981 1981 CD cord-005646-xhx9pzhj 2208 33 till till IN cord-005646-xhx9pzhj 2208 34 december december NNP cord-005646-xhx9pzhj 2208 35 1991 1991 CD cord-005646-xhx9pzhj 2208 36 . . . cord-005646-xhx9pzhj 2209 1 Patients patient NNS cord-005646-xhx9pzhj 2209 2 with with IN cord-005646-xhx9pzhj 2209 3 a a DT cord-005646-xhx9pzhj 2209 4 history history NN cord-005646-xhx9pzhj 2209 5 of of IN cord-005646-xhx9pzhj 2209 6 neurologic neurologic JJ cord-005646-xhx9pzhj 2209 7 disorders disorder NNS cord-005646-xhx9pzhj 2209 8 were be VBD cord-005646-xhx9pzhj 2209 9 excluded exclude VBN cord-005646-xhx9pzhj 2209 10 . . . cord-005646-xhx9pzhj 2210 1 57 57 CD cord-005646-xhx9pzhj 2210 2 Patients patient NNS cord-005646-xhx9pzhj 2210 3 were be VBD cord-005646-xhx9pzhj 2210 4 identified identify VBN cord-005646-xhx9pzhj 2210 5 , , , cord-005646-xhx9pzhj 2210 6 65 65 CD cord-005646-xhx9pzhj 2210 7 % % NN cord-005646-xhx9pzhj 2210 8 were be VBD cord-005646-xhx9pzhj 2210 9 male male JJ cord-005646-xhx9pzhj 2210 10 . . . cord-005646-xhx9pzhj 2211 1 The the DT cord-005646-xhx9pzhj 2211 2 cause cause NN cord-005646-xhx9pzhj 2211 3 of of IN cord-005646-xhx9pzhj 2211 4 the the DT cord-005646-xhx9pzhj 2211 5 fever fever NN cord-005646-xhx9pzhj 2211 6 remained remain VBD cord-005646-xhx9pzhj 2211 7 unknown unknown JJ cord-005646-xhx9pzhj 2211 8 in in IN cord-005646-xhx9pzhj 2211 9 51 51 CD cord-005646-xhx9pzhj 2211 10 % % NN cord-005646-xhx9pzhj 2211 11 of of IN cord-005646-xhx9pzhj 2211 12 the the DT cord-005646-xhx9pzhj 2211 13 cases case NNS cord-005646-xhx9pzhj 2211 14 . . . cord-005646-xhx9pzhj 2212 1 In in IN cord-005646-xhx9pzhj 2212 2 all all DT cord-005646-xhx9pzhj 2212 3 case case NN cord-005646-xhx9pzhj 2212 4 the the DT cord-005646-xhx9pzhj 2212 5 FSE FSE NNP cord-005646-xhx9pzhj 2212 6 was be VBD cord-005646-xhx9pzhj 2212 7 generalized generalize VBN cord-005646-xhx9pzhj 2212 8 and and CC cord-005646-xhx9pzhj 2212 9 it -PRON- PRP cord-005646-xhx9pzhj 2212 10 most most RBS cord-005646-xhx9pzhj 2212 11 frequently frequently RB cord-005646-xhx9pzhj 2212 12 occurred occur VBD cord-005646-xhx9pzhj 2212 13 at at IN cord-005646-xhx9pzhj 2212 14 night night NN cord-005646-xhx9pzhj 2212 15 ( ( -LRB- cord-005646-xhx9pzhj 2212 16 47 47 CD cord-005646-xhx9pzhj 2212 17 % % NN cord-005646-xhx9pzhj 2212 18 ) ) -RRB- cord-005646-xhx9pzhj 2212 19 . . . cord-005646-xhx9pzhj 2213 1 The the DT cord-005646-xhx9pzhj 2213 2 mean mean JJ cord-005646-xhx9pzhj 2213 3 age age NN cord-005646-xhx9pzhj 2213 4 at at IN cord-005646-xhx9pzhj 2213 5 FSE FSE NNP cord-005646-xhx9pzhj 2213 6 was be VBD cord-005646-xhx9pzhj 2213 7 t.6 t.6 CD cord-005646-xhx9pzhj 2213 8 years year NNS cord-005646-xhx9pzhj 2213 9 ( ( -LRB- cord-005646-xhx9pzhj 2213 10 0.5 0.5 CD cord-005646-xhx9pzhj 2213 11 - - SYM cord-005646-xhx9pzhj 2213 12 4.7 4.7 CD cord-005646-xhx9pzhj 2213 13 ) ) -RRB- cord-005646-xhx9pzhj 2213 14 , , , cord-005646-xhx9pzhj 2213 15 the the DT cord-005646-xhx9pzhj 2213 16 mean mean JJ cord-005646-xhx9pzhj 2213 17 temperature temperature NN cord-005646-xhx9pzhj 2213 18 39.6 39.6 CD cord-005646-xhx9pzhj 2213 19 ° ° NN cord-005646-xhx9pzhj 2214 1 C C NNP cord-005646-xhx9pzhj 2214 2 ( ( -LRB- cord-005646-xhx9pzhj 2214 3 38.5 38.5 CD cord-005646-xhx9pzhj 2214 4 - - SYM cord-005646-xhx9pzhj 2214 5 40 40 CD cord-005646-xhx9pzhj 2214 6 ° ° NN cord-005646-xhx9pzhj 2214 7 C c NN cord-005646-xhx9pzhj 2214 8 ) ) -RRB- cord-005646-xhx9pzhj 2214 9 . . . cord-005646-xhx9pzhj 2215 1 The the DT cord-005646-xhx9pzhj 2215 2 mean mean JJ cord-005646-xhx9pzhj 2215 3 follow follow VBP cord-005646-xhx9pzhj 2215 4 up up RP cord-005646-xhx9pzhj 2215 5 time time NN cord-005646-xhx9pzhj 2215 6 was be VBD cord-005646-xhx9pzhj 2215 7 1.7 1.7 CD cord-005646-xhx9pzhj 2215 8 year year NN cord-005646-xhx9pzhj 2215 9 . . . cord-005646-xhx9pzhj 2216 1 Twelve twelve CD cord-005646-xhx9pzhj 2216 2 children child NNS cord-005646-xhx9pzhj 2216 3 ( ( -LRB- cord-005646-xhx9pzhj 2216 4 21 21 CD cord-005646-xhx9pzhj 2216 5 % % NN cord-005646-xhx9pzhj 2216 6 ) ) -RRB- cord-005646-xhx9pzhj 2216 7 had have VBD cord-005646-xhx9pzhj 2216 8 neurologic neurologic JJ cord-005646-xhx9pzhj 2216 9 sequelea sequelea NN cord-005646-xhx9pzhj 2216 10 . . . cord-005646-xhx9pzhj 2217 1 The the DT cord-005646-xhx9pzhj 2217 2 neurologic neurologic JJ cord-005646-xhx9pzhj 2217 3 sequelae sequela NNS cord-005646-xhx9pzhj 2217 4 varied varied JJ cord-005646-xhx9pzhj 2217 5 from from IN cord-005646-xhx9pzhj 2217 6 speech speech NN cord-005646-xhx9pzhj 2217 7 deficit deficit NN cord-005646-xhx9pzhj 2217 8 ( ( -LRB- cord-005646-xhx9pzhj 2217 9 4 4 CD cord-005646-xhx9pzhj 2217 10 case case NN cord-005646-xhx9pzhj 2217 11 mild mild JJ cord-005646-xhx9pzhj 2217 12 , , , cord-005646-xhx9pzhj 2217 13 V2 V2 NNP cord-005646-xhx9pzhj 2217 14 -1 -1 NN cord-005646-xhx9pzhj 2217 15 year year NN cord-005646-xhx9pzhj 2217 16 delayed delay VBN cord-005646-xhx9pzhj 2217 17 ; ; : cord-005646-xhx9pzhj 2217 18 4 4 CD cord-005646-xhx9pzhj 2217 19 case case NN cord-005646-xhx9pzhj 2217 20 moderate moderate JJ cord-005646-xhx9pzhj 2217 21 > > XX cord-005646-xhx9pzhj 2217 22 1 1 CD cord-005646-xhx9pzhj 2217 23 year year NN cord-005646-xhx9pzhj 2217 24 delayed delay VBN cord-005646-xhx9pzhj 2217 25 ) ) -RRB- cord-005646-xhx9pzhj 2217 26 to to IN cord-005646-xhx9pzhj 2217 27 severe severe JJ cord-005646-xhx9pzhj 2217 28 retardation retardation NN cord-005646-xhx9pzhj 2217 29 and and CC cord-005646-xhx9pzhj 2217 30 epilepsy epilepsy NN cord-005646-xhx9pzhj 2217 31 ( ( -LRB- cord-005646-xhx9pzhj 2217 32 4 4 CD cord-005646-xhx9pzhj 2217 33 cases case NNS cord-005646-xhx9pzhj 2217 34 ) ) -RRB- cord-005646-xhx9pzhj 2217 35 . . . cord-005646-xhx9pzhj 2218 1 Speech speech NN cord-005646-xhx9pzhj 2218 2 deficit deficit NN cord-005646-xhx9pzhj 2218 3 was be VBD cord-005646-xhx9pzhj 2218 4 detected detect VBN cord-005646-xhx9pzhj 2218 5 after after IN cord-005646-xhx9pzhj 2218 6 a a DT cord-005646-xhx9pzhj 2218 7 mean mean JJ cord-005646-xhx9pzhj 2218 8 period period NN cord-005646-xhx9pzhj 2218 9 of of IN cord-005646-xhx9pzhj 2218 10 6 6 CD cord-005646-xhx9pzhj 2218 11 months month NNS cord-005646-xhx9pzhj 2218 12 ( ( -LRB- cord-005646-xhx9pzhj 2218 13 range range VBP cord-005646-xhx9pzhj 2218 14 0 0 CD cord-005646-xhx9pzhj 2218 15 - - SYM cord-005646-xhx9pzhj 2218 16 18 18 CD cord-005646-xhx9pzhj 2218 17 ) ) -RRB- cord-005646-xhx9pzhj 2218 18 , , , cord-005646-xhx9pzhj 2218 19 Age age NN cord-005646-xhx9pzhj 2218 20 , , , cord-005646-xhx9pzhj 2218 21 gender gender NN cord-005646-xhx9pzhj 2218 22 , , , cord-005646-xhx9pzhj 2218 23 temperature temperature NN cord-005646-xhx9pzhj 2218 24 , , , cord-005646-xhx9pzhj 2218 25 family family NN cord-005646-xhx9pzhj 2218 26 history history NN cord-005646-xhx9pzhj 2218 27 and and CC cord-005646-xhx9pzhj 2218 28 time time NN cord-005646-xhx9pzhj 2218 29 of of IN cord-005646-xhx9pzhj 2218 30 onset onset NN cord-005646-xhx9pzhj 2218 31 were be VBD cord-005646-xhx9pzhj 2218 32 no no DT cord-005646-xhx9pzhj 2218 33 significant significant JJ cord-005646-xhx9pzhj 2218 34 risk risk NN cord-005646-xhx9pzhj 2218 35 factors factor NNS cord-005646-xhx9pzhj 2218 36 for for IN cord-005646-xhx9pzhj 2218 37 neurologic neurologic JJ cord-005646-xhx9pzhj 2218 38 sequelae sequela NNS cord-005646-xhx9pzhj 2218 39 . . . cord-005646-xhx9pzhj 2219 1 Duration duration NN cord-005646-xhx9pzhj 2219 2 of of IN cord-005646-xhx9pzhj 2219 3 seizure seizure NN cord-005646-xhx9pzhj 2219 4 [ [ -LRB- cord-005646-xhx9pzhj 2219 5 RR RR NNP cord-005646-xhx9pzhj 2219 6 3.0 3.0 CD cord-005646-xhx9pzhj 2219 7 ( ( -LRB- cord-005646-xhx9pzhj 2219 8 0.8 0.8 CD cord-005646-xhx9pzhj 2219 9 - - SYM cord-005646-xhx9pzhj 2219 10 11.3 11.3 CD cord-005646-xhx9pzhj 2219 11 ) ) -RRB- cord-005646-xhx9pzhj 2219 12 ] ] -RRB- cord-005646-xhx9pzhj 2219 13 and and CC cord-005646-xhx9pzhj 2219 14 more more JJR cord-005646-xhx9pzhj 2219 15 than than IN cord-005646-xhx9pzhj 2219 16 two two CD cord-005646-xhx9pzhj 2219 17 drugs drug NNS cord-005646-xhx9pzhj 2219 18 to to TO cord-005646-xhx9pzhj 2219 19 treat treat VB cord-005646-xhx9pzhj 2219 20 FSE FSE NNP cord-005646-xhx9pzhj 2219 21 ( ( -LRB- cord-005646-xhx9pzhj 2219 22 RR RR NNP cord-005646-xhx9pzhj 2219 23 5.2 5.2 CD cord-005646-xhx9pzhj 2220 1 ( ( -LRB- cord-005646-xhx9pzhj 2220 2 t.5 t.5 NNP cord-005646-xhx9pzhj 2220 3 - - HYPH cord-005646-xhx9pzhj 2220 4 18.1 18.1 CD cord-005646-xhx9pzhj 2220 5 ) ) -RRB- cord-005646-xhx9pzhj 2220 6 were be VBD cord-005646-xhx9pzhj 2220 7 related relate VBN cord-005646-xhx9pzhj 2220 8 to to IN cord-005646-xhx9pzhj 2220 9 neurologic neurologic JJ cord-005646-xhx9pzhj 2220 10 sequelae sequela NNS cord-005646-xhx9pzhj 2220 11 . . . cord-005646-xhx9pzhj 2221 1 We -PRON- PRP cord-005646-xhx9pzhj 2221 2 recommend recommend VBP cord-005646-xhx9pzhj 2221 3 that that IN cord-005646-xhx9pzhj 2221 4 FSE FSE NNP cord-005646-xhx9pzhj 2221 5 children child NNS cord-005646-xhx9pzhj 2221 6 should should MD cord-005646-xhx9pzhj 2221 7 be be VB cord-005646-xhx9pzhj 2221 8 followed follow VBN cord-005646-xhx9pzhj 2221 9 for for IN cord-005646-xhx9pzhj 2221 10 at at RB cord-005646-xhx9pzhj 2221 11 least least RBS cord-005646-xhx9pzhj 2221 12 a a DT cord-005646-xhx9pzhj 2221 13 year year NN cord-005646-xhx9pzhj 2221 14 to to TO cord-005646-xhx9pzhj 2221 15 detect detect VB cord-005646-xhx9pzhj 2221 16 possible possible JJ cord-005646-xhx9pzhj 2221 17 speech speech NN cord-005646-xhx9pzhj 2221 18 disorders disorder NNS cord-005646-xhx9pzhj 2221 19 properly properly RB cord-005646-xhx9pzhj 2221 20 and and CC cord-005646-xhx9pzhj 2221 21 start start VB cord-005646-xhx9pzhj 2221 22 early early JJ cord-005646-xhx9pzhj 2221 23 intervention intervention NN cord-005646-xhx9pzhj 2221 24 . . . cord-005646-xhx9pzhj 2222 1 UNUSUAL unusual JJ cord-005646-xhx9pzhj 2222 2 PRESENTATION presentation NN cord-005646-xhx9pzhj 2222 3 OF of IN cord-005646-xhx9pzhj 2222 4 MYASTHENLg MYASTHENLg NNS cord-005646-xhx9pzhj 2222 5 GRA%qS GRA%qS NNP cord-005646-xhx9pzhj 2222 6 IBtZA IBtZA NNP cord-005646-xhx9pzhj 2222 7 E. E. NNP cord-005646-xhx9pzhj 2222 8 MODESTO MODESTO NNP cord-005646-xhx9pzhj 2222 9 , , , cord-005646-xhx9pzhj 2222 10 V~ V~ NNP cord-005646-xhx9pzhj 2222 11 ABE ABE NNP cord-005646-xhx9pzhj 2222 12 ~ ~ NFP cord-005646-xhx9pzhj 2222 13 GOCHEA GOCHEA NNP cord-005646-xhx9pzhj 2222 14 A A NNP cord-005646-xhx9pzhj 2222 15 , , , cord-005646-xhx9pzhj 2222 16 SANCH]S SANCH]S NNP cord-005646-xhx9pzhj 2222 17 1L 1l CD cord-005646-xhx9pzhj 2222 18 AlL all DT cord-005646-xhx9pzhj 2222 19 , , , cord-005646-xhx9pzhj 2222 20 GO GO NNP cord-005646-xhx9pzhj 2222 21 L L NNP cord-005646-xhx9pzhj 2222 22 VARAS VARAS NNP cord-005646-xhx9pzhj 2223 1 K K NNP cord-005646-xhx9pzhj 2223 2 FOLGADO FOLGADO NNP cord-005646-xhx9pzhj 2223 3 S S NNP cord-005646-xhx9pzhj 2223 4 , , , cord-005646-xhx9pzhj 2223 5 GARCIA GARCIA NNP cord-005646-xhx9pzhj 2223 6 E. E. NNP cord-005646-xhx9pzhj 2223 7 P.1.C.U. P.1.C.U. NNP cord-005646-xhx9pzhj 2223 8 LA LA NNP cord-005646-xhx9pzhj 2223 9 FE FE NNP cord-005646-xhx9pzhj 2223 10 , , , cord-005646-xhx9pzhj 2223 11 Valencia Valencia NNP cord-005646-xhx9pzhj 2223 12 . . . cord-005646-xhx9pzhj 2224 1 Spain Spain NNP cord-005646-xhx9pzhj 2224 2 CASE CASE NNP cord-005646-xhx9pzhj 2224 3 REPORT REPORT NNP cord-005646-xhx9pzhj 2224 4 : : : cord-005646-xhx9pzhj 2225 1 The the DT cord-005646-xhx9pzhj 2225 2 patient patient NN cord-005646-xhx9pzhj 2225 3 was be VBD cord-005646-xhx9pzhj 2225 4 a a DT cord-005646-xhx9pzhj 2225 5 2-year 2-year CD cord-005646-xhx9pzhj 2225 6 - - HYPH cord-005646-xhx9pzhj 2225 7 o!d o!d JJ cord-005646-xhx9pzhj 2225 8 gift gift NN cord-005646-xhx9pzhj 2225 9 transferred transfer VBN cord-005646-xhx9pzhj 2225 10 to to IN cord-005646-xhx9pzhj 2225 11 our -PRON- PRP$ cord-005646-xhx9pzhj 2225 12 PIC pic NN cord-005646-xhx9pzhj 2225 13 because because IN cord-005646-xhx9pzhj 2225 14 of of IN cord-005646-xhx9pzhj 2225 15 severe severe JJ cord-005646-xhx9pzhj 2225 16 respiratory respiratory JJ cord-005646-xhx9pzhj 2225 17 failure failure NN cord-005646-xhx9pzhj 2225 18 . . . cord-005646-xhx9pzhj 2226 1 The the DT cord-005646-xhx9pzhj 2226 2 patient patient NN cord-005646-xhx9pzhj 2226 3 , , , cord-005646-xhx9pzhj 2226 4 convaleseem convaleseem NNP cord-005646-xhx9pzhj 2226 5 of of IN cord-005646-xhx9pzhj 2226 6 ehiekenpox ehiekenpox NNP cord-005646-xhx9pzhj 2226 7 , , , cord-005646-xhx9pzhj 2226 8 came come VBD cord-005646-xhx9pzhj 2226 9 into into IN cord-005646-xhx9pzhj 2226 10 contact contact NN cord-005646-xhx9pzhj 2226 11 with with IN cord-005646-xhx9pzhj 2226 12 horse horse NN cord-005646-xhx9pzhj 2226 13 manure manure NN cord-005646-xhx9pzhj 2226 14 previous previous JJ cord-005646-xhx9pzhj 2226 15 afternoon afternoon NN cord-005646-xhx9pzhj 2226 16 . . . cord-005646-xhx9pzhj 2227 1 In in IN cord-005646-xhx9pzhj 2227 2 the the DT cord-005646-xhx9pzhj 2227 3 morning morning NN cord-005646-xhx9pzhj 2227 4 , , , cord-005646-xhx9pzhj 2227 5 she -PRON- PRP cord-005646-xhx9pzhj 2227 6 was be VBD cord-005646-xhx9pzhj 2227 7 lethargy lethargy NN cord-005646-xhx9pzhj 2227 8 , , , cord-005646-xhx9pzhj 2227 9 and and CC cord-005646-xhx9pzhj 2227 10 irritability irritability NN cord-005646-xhx9pzhj 2227 11 , , , cord-005646-xhx9pzhj 2227 12 with with IN cord-005646-xhx9pzhj 2227 13 poor poor JJ cord-005646-xhx9pzhj 2227 14 finding finding NN cord-005646-xhx9pzhj 2227 15 , , , cord-005646-xhx9pzhj 2227 16 and and CC cord-005646-xhx9pzhj 2227 17 ~ ~ NFP cord-005646-xhx9pzhj 2227 18 an an DT cord-005646-xhx9pzhj 2227 19 episode episode NN cord-005646-xhx9pzhj 2227 20 of of IN cord-005646-xhx9pzhj 2227 21 coughing coughing NN cord-005646-xhx9pzhj 2227 22 , , , cord-005646-xhx9pzhj 2227 23 cyanosis cyanosis NN cord-005646-xhx9pzhj 2227 24 and and CC cord-005646-xhx9pzhj 2227 25 acute acute JJ cord-005646-xhx9pzhj 2227 26 respiratory respiratory JJ cord-005646-xhx9pzhj 2227 27 failure failure NN cord-005646-xhx9pzhj 2227 28 after after IN cord-005646-xhx9pzhj 2227 29 mucous mucous JJ cord-005646-xhx9pzhj 2227 30 vomiting vomiting NN cord-005646-xhx9pzhj 2227 31 when when WRB cord-005646-xhx9pzhj 2227 32 she -PRON- PRP cord-005646-xhx9pzhj 2227 33 was be VBD cord-005646-xhx9pzhj 2227 34 drinking drink VBG cord-005646-xhx9pzhj 2227 35 milk milk NN cord-005646-xhx9pzhj 2227 36 . . . cord-005646-xhx9pzhj 2228 1 On on IN cord-005646-xhx9pzhj 2228 2 admission admission NN cord-005646-xhx9pzhj 2228 3 she -PRON- PRP cord-005646-xhx9pzhj 2228 4 had have VBD cord-005646-xhx9pzhj 2228 5 severe severe JJ cord-005646-xhx9pzhj 2228 6 respiratory respiratory JJ cord-005646-xhx9pzhj 2228 7 distress distress NN cord-005646-xhx9pzhj 2228 8 , , , cord-005646-xhx9pzhj 2228 9 respiratory respiratory JJ cord-005646-xhx9pzhj 2228 10 acidosis acidosis NN cord-005646-xhx9pzhj 2228 11 , , , cord-005646-xhx9pzhj 2228 12 and and CC cord-005646-xhx9pzhj 2228 13 the the DT cord-005646-xhx9pzhj 2228 14 Sat Sat NNP cord-005646-xhx9pzhj 2229 1 02 02 CD cord-005646-xhx9pzhj 2229 2 was be VBD cord-005646-xhx9pzhj 2229 3 86 86 CD cord-005646-xhx9pzhj 2229 4 % % NN cord-005646-xhx9pzhj 2229 5 . . . cord-005646-xhx9pzhj 2230 1 She -PRON- PRP cord-005646-xhx9pzhj 2230 2 was be VBD cord-005646-xhx9pzhj 2230 3 mtubated mtubate VBN cord-005646-xhx9pzhj 2230 4 without without IN cord-005646-xhx9pzhj 2230 5 difficulty difficulty NN cord-005646-xhx9pzhj 2230 6 , , , cord-005646-xhx9pzhj 2230 7 and and CC cord-005646-xhx9pzhj 2230 8 was be VBD cord-005646-xhx9pzhj 2230 9 transferred transfer VBN cord-005646-xhx9pzhj 2230 10 to to IN cord-005646-xhx9pzhj 2230 11 our -PRON- PRP$ cord-005646-xhx9pzhj 2230 12 P.I.C.U. P.I.C.U. NNP cord-005646-xhx9pzhj 2230 13 Physical Physical NNP cord-005646-xhx9pzhj 2230 14 examination examination NN cord-005646-xhx9pzhj 2230 15 reveals reveal VBZ cord-005646-xhx9pzhj 2230 16 stable stable JJ cord-005646-xhx9pzhj 2230 17 hemodynamies hemodynamie NNS cord-005646-xhx9pzhj 2230 18 , , , cord-005646-xhx9pzhj 2230 19 pupils pupil NNS cord-005646-xhx9pzhj 2230 20 equal equal JJ cord-005646-xhx9pzhj 2230 21 , , , cord-005646-xhx9pzhj 2230 22 round round JJ cord-005646-xhx9pzhj 2230 23 , , , cord-005646-xhx9pzhj 2230 24 reactive reactive JJ cord-005646-xhx9pzhj 2230 25 to to IN cord-005646-xhx9pzhj 2230 26 light light JJ cord-005646-xhx9pzhj 2230 27 , , , cord-005646-xhx9pzhj 2230 28 normal normal JJ cord-005646-xhx9pzhj 2230 29 fandi fandi NN cord-005646-xhx9pzhj 2230 30 , , , cord-005646-xhx9pzhj 2230 31 and and CC cord-005646-xhx9pzhj 2230 32 muscle muscle NN cord-005646-xhx9pzhj 2230 33 relaxation relaxation NN cord-005646-xhx9pzhj 2230 34 . . . cord-005646-xhx9pzhj 2231 1 Crusted crusted JJ cord-005646-xhx9pzhj 2231 2 vesicles vesicle NNS cord-005646-xhx9pzhj 2231 3 diseminats diseminat NNS cord-005646-xhx9pzhj 2232 1 ~d ~d ADD cord-005646-xhx9pzhj 2232 2 . . . cord-005646-xhx9pzhj 2233 1 Rhonehi Rhonehi NNP cord-005646-xhx9pzhj 2233 2 over over IN cord-005646-xhx9pzhj 2233 3 both both DT cord-005646-xhx9pzhj 2233 4 lungs lung NNS cord-005646-xhx9pzhj 2233 5 . . . cord-005646-xhx9pzhj 2234 1 Hepatomegaly Hepatomegaly NNP cord-005646-xhx9pzhj 2234 2 ( ( -LRB- cord-005646-xhx9pzhj 2234 3 + + NN cord-005646-xhx9pzhj 2234 4 ) ) -RRB- cord-005646-xhx9pzhj 2234 5 and and CC cord-005646-xhx9pzhj 2234 6 splenomegaly splenomegaly NN cord-005646-xhx9pzhj 2234 7 ( ( -LRB- cord-005646-xhx9pzhj 2234 8 + + CD cord-005646-xhx9pzhj 2234 9 ) ) -RRB- cord-005646-xhx9pzhj 2234 10 . . . cord-005646-xhx9pzhj 2235 1 ~lhe ~lhe NNP cord-005646-xhx9pzhj 2235 2 urine urine NN cord-005646-xhx9pzhj 2235 3 , , , cord-005646-xhx9pzhj 2235 4 hematologic hematologic JJ cord-005646-xhx9pzhj 2235 5 , , , cord-005646-xhx9pzhj 2235 6 and and CC cord-005646-xhx9pzhj 2235 7 C.S.F. C.S.F. NNP cord-005646-xhx9pzhj 2235 8 laboratory laboratory NN cord-005646-xhx9pzhj 2235 9 findings finding NNS cord-005646-xhx9pzhj 2235 10 were be VBD cord-005646-xhx9pzhj 2235 11 normal normal JJ cord-005646-xhx9pzhj 2235 12 . . . cord-005646-xhx9pzhj 2236 1 C.T. C.T. NNP cord-005646-xhx9pzhj 2236 2 scan scan NN cord-005646-xhx9pzhj 2236 3 of of IN cord-005646-xhx9pzhj 2236 4 the the DT cord-005646-xhx9pzhj 2236 5 brain brain NN cord-005646-xhx9pzhj 2236 6 , , , cord-005646-xhx9pzhj 2236 7 E.E.G. E.E.G. NNP cord-005646-xhx9pzhj 2236 8 , , , cord-005646-xhx9pzhj 2236 9 and and CC cord-005646-xhx9pzhj 2236 10 EKG EKG NNP cord-005646-xhx9pzhj 2236 11 . . . cord-005646-xhx9pzhj 2237 1 revealed reveal VBN cord-005646-xhx9pzhj 2237 2 no'abnormalities no'abnormalities NNPS cord-005646-xhx9pzhj 2237 3 . . . cord-005646-xhx9pzhj 2238 1 Rx Rx NNP cord-005646-xhx9pzhj 2238 2 chest chest NN cord-005646-xhx9pzhj 2238 3 disclosed disclose VBD cord-005646-xhx9pzhj 2238 4 a a DT cord-005646-xhx9pzhj 2238 5 retrocardiac retrocardiac NNP cord-005646-xhx9pzhj 2238 6 atelectasis atelectasis NN cord-005646-xhx9pzhj 2238 7 . . . cord-005646-xhx9pzhj 2239 1 Speci Speci NNP cord-005646-xhx9pzhj 2239 2 ~ ~ NFP cord-005646-xhx9pzhj 2239 3 ts ts NN cord-005646-xhx9pzhj 2239 4 of of IN cord-005646-xhx9pzhj 2239 5 stool stool NN cord-005646-xhx9pzhj 2239 6 and and CC cord-005646-xhx9pzhj 2239 7 blood blood NN cord-005646-xhx9pzhj 2239 8 were be VBD cord-005646-xhx9pzhj 2239 9 obtained obtain VBN cord-005646-xhx9pzhj 2239 10 for for IN cord-005646-xhx9pzhj 2239 11 cultures culture NNS cord-005646-xhx9pzhj 2239 12 and and CC cord-005646-xhx9pzhj 2239 13 study study NN cord-005646-xhx9pzhj 2239 14 of of IN cord-005646-xhx9pzhj 2239 15 C. C. NNP cord-005646-xhx9pzhj 2239 16 botul#num botul#num IN cord-005646-xhx9pzhj 2239 17 toxins toxin NNS cord-005646-xhx9pzhj 2239 18 . . . cord-005646-xhx9pzhj 2240 1 Pending pende VBG cord-005646-xhx9pzhj 2240 2 receipt receipt NN cord-005646-xhx9pzhj 2240 3 of of IN cord-005646-xhx9pzhj 2240 4 these these DT cord-005646-xhx9pzhj 2240 5 results result NNS cord-005646-xhx9pzhj 2240 6 , , , cord-005646-xhx9pzhj 2240 7 a a DT cord-005646-xhx9pzhj 2240 8 broad broad RB cord-005646-xhx9pzhj 2240 9 - - HYPH cord-005646-xhx9pzhj 2240 10 speotmm speotmm NN cord-005646-xhx9pzhj 2240 11 antibiotic antibiotic NN cord-005646-xhx9pzhj 2240 12 and and CC cord-005646-xhx9pzhj 2240 13 acyctovir acyctovir NNP cord-005646-xhx9pzhj 2240 14 was be VBD cord-005646-xhx9pzhj 2240 15 begun begin VBN cord-005646-xhx9pzhj 2240 16 . . . cord-005646-xhx9pzhj 2241 1 The the DT cord-005646-xhx9pzhj 2241 2 initial initial JJ cord-005646-xhx9pzhj 2241 3 differennal differennal JJ cord-005646-xhx9pzhj 2241 4 diagnosis diagnosis NN cord-005646-xhx9pzhj 2241 5 consisted consist VBD cord-005646-xhx9pzhj 2241 6 of of IN cord-005646-xhx9pzhj 2241 7 LARYNGOSPASM LARYNGOSPASM NNP cord-005646-xhx9pzhj 2241 8 ASSOCIATED ASSOCIATED NNP cord-005646-xhx9pzhj 2241 9 WITH with IN cord-005646-xhx9pzhj 2241 10 ASPIRAqlON aspiraqlon NN cord-005646-xhx9pzhj 2241 11 , , , cord-005646-xhx9pzhj 2241 12 botulism botulism NN cord-005646-xhx9pzhj 2241 13 , , , cord-005646-xhx9pzhj 2241 14 and and CC cord-005646-xhx9pzhj 2241 15 postmfecfious postmfecfious JJ cord-005646-xhx9pzhj 2241 16 varicella varicella NNP cord-005646-xhx9pzhj 2241 17 encephalitis encephalitis RB cord-005646-xhx9pzhj 2241 18 . . . cord-005646-xhx9pzhj 2242 1 After after IN cord-005646-xhx9pzhj 2242 2 15 15 CD cord-005646-xhx9pzhj 2242 3 hours hour NNS cord-005646-xhx9pzhj 2242 4 , , , cord-005646-xhx9pzhj 2242 5 weatm~ weatm~ NNP cord-005646-xhx9pzhj 2242 6 was be VBD cord-005646-xhx9pzhj 2242 7 begun begin VBN cord-005646-xhx9pzhj 2242 8 . . . cord-005646-xhx9pzhj 2243 1 The the DT cord-005646-xhx9pzhj 2243 2 neurologic neurologic JJ cord-005646-xhx9pzhj 2243 3 examination examination NN cord-005646-xhx9pzhj 2243 4 showed show VBD cord-005646-xhx9pzhj 2243 5 a a DT cord-005646-xhx9pzhj 2243 6 low low JJ cord-005646-xhx9pzhj 2243 7 Modified modify VBN cord-005646-xhx9pzhj 2243 8 Glasgow Glasgow NNP cord-005646-xhx9pzhj 2243 9 Coma Coma NNP cord-005646-xhx9pzhj 2244 1 ~ale ~ale NNP cord-005646-xhx9pzhj 2244 2 ( ( -LRB- cord-005646-xhx9pzhj 2244 3 MGCS MGCS NNP cord-005646-xhx9pzhj 2244 4 ) ) -RRB- cord-005646-xhx9pzhj 2244 5 , , , cord-005646-xhx9pzhj 2244 6 generalized generalize VBN cord-005646-xhx9pzhj 2244 7 hypotouia hypotouia NN cord-005646-xhx9pzhj 2244 8 and and CC cord-005646-xhx9pzhj 2244 9 muscle muscle NN cord-005646-xhx9pzhj 2244 10 weakness weakness NN cord-005646-xhx9pzhj 2244 11 . . . cord-005646-xhx9pzhj 2245 1 These these DT cord-005646-xhx9pzhj 2245 2 data datum NNS cord-005646-xhx9pzhj 2245 3 suggested suggest VBD cord-005646-xhx9pzhj 2245 4 three three CD cord-005646-xhx9pzhj 2245 5 diagnoses diagnosis NNS cord-005646-xhx9pzhj 2245 6 , , , cord-005646-xhx9pzhj 2245 7 posfnfecfious posfnfecfious JJ cord-005646-xhx9pzhj 2245 8 encephalitis encephalitis NN cord-005646-xhx9pzhj 2245 9 , , , cord-005646-xhx9pzhj 2245 10 residual residual JJ cord-005646-xhx9pzhj 2245 11 neuroumsoAar neuroumsoAar NNP cord-005646-xhx9pzhj 2245 12 blockade blockade NN cord-005646-xhx9pzhj 2245 13 , , , cord-005646-xhx9pzhj 2245 14 and and CC cord-005646-xhx9pzhj 2245 15 excessive excessive JJ cord-005646-xhx9pzhj 2245 16 doses dose NNS cord-005646-xhx9pzhj 2245 17 of of IN cord-005646-xhx9pzhj 2245 18 sedative sedative JJ cord-005646-xhx9pzhj 2245 19 and and CC cord-005646-xhx9pzhj 2245 20 analgesic analgesic JJ cord-005646-xhx9pzhj 2245 21 drugs drug NNS cord-005646-xhx9pzhj 2245 22 . . . cord-005646-xhx9pzhj 2246 1 After after IN cord-005646-xhx9pzhj 2246 2 20 20 CD cord-005646-xhx9pzhj 2246 3 hours hour NNS cord-005646-xhx9pzhj 2246 4 she -PRON- PRP cord-005646-xhx9pzhj 2246 5 regained regain VBD cord-005646-xhx9pzhj 2246 6 skeletal skeletal JJ cord-005646-xhx9pzhj 2246 7 muscle muscle NN cord-005646-xhx9pzhj 2246 8 poxver poxver NN cord-005646-xhx9pzhj 2246 9 and and CC cord-005646-xhx9pzhj 2246 10 ufltlcient ufltlcient JJ cord-005646-xhx9pzhj 2246 11 respiratory respiratory JJ cord-005646-xhx9pzhj 2246 12 effort effort NN cord-005646-xhx9pzhj 2246 13 , , , cord-005646-xhx9pzhj 2246 14 the the DT cord-005646-xhx9pzhj 2246 15 MCGS MCGS NNP cord-005646-xhx9pzhj 2246 16 was be VBD cord-005646-xhx9pzhj 2246 17 acceptable acceptable JJ cord-005646-xhx9pzhj 2246 18 , , , cord-005646-xhx9pzhj 2246 19 and and CC cord-005646-xhx9pzhj 2246 20 blood blood NN cord-005646-xhx9pzhj 2246 21 gases gas NNS cord-005646-xhx9pzhj 2246 22 were be VBD cord-005646-xhx9pzhj 2246 23 normal normal JJ cord-005646-xhx9pzhj 2246 24 . . . cord-005646-xhx9pzhj 2247 1 She -PRON- PRP cord-005646-xhx9pzhj 2247 2 was be VBD cord-005646-xhx9pzhj 2247 3 given give VBN cord-005646-xhx9pzhj 2247 4 n~-tigmine n~-tigmine JJ cord-005646-xhx9pzhj 2247 5 and and CC cord-005646-xhx9pzhj 2247 6 atropine atropine NN cord-005646-xhx9pzhj 2247 7 , , , cord-005646-xhx9pzhj 2247 8 and and CC cord-005646-xhx9pzhj 2247 9 her -PRON- PRP$ cord-005646-xhx9pzhj 2247 10 tr tr NNP cord-005646-xhx9pzhj 2247 11 ~ ~ NNP cord-005646-xhx9pzhj 2247 12 ma ma NNP cord-005646-xhx9pzhj 2247 13 was be VBD cord-005646-xhx9pzhj 2247 14 extubated extubate VBN cord-005646-xhx9pzhj 2247 15 . . . cord-005646-xhx9pzhj 2248 1 An an DT cord-005646-xhx9pzhj 2248 2 acute acute JJ cord-005646-xhx9pzhj 2248 3 respiratory respiratory JJ cord-005646-xhx9pzhj 2248 4 failure failure NN cord-005646-xhx9pzhj 2248 5 ocurrs ocurrs NNP cord-005646-xhx9pzhj 2248 6 120 120 CD cord-005646-xhx9pzhj 2248 7 ram ram NN cord-005646-xhx9pzhj 2248 8 . . . cord-005646-xhx9pzhj 2249 1 after after RB cord-005646-xhx9pzhj 2249 2 . . . cord-005646-xhx9pzhj 2250 1 Chest chest NN cord-005646-xhx9pzhj 2250 2 radioga'aph radioga'aph , cord-005646-xhx9pzhj 2250 3 disclosed disclose VBD cord-005646-xhx9pzhj 2250 4 a a DT cord-005646-xhx9pzhj 2250 5 left left JJ cord-005646-xhx9pzhj 2250 6 inferior inferior JJ cord-005646-xhx9pzhj 2250 7 lobe lobe NN cord-005646-xhx9pzhj 2250 8 atelectasis atelectasis NN cord-005646-xhx9pzhj 2250 9 . . . cord-005646-xhx9pzhj 2251 1 After after IN cord-005646-xhx9pzhj 2251 2 20 20 CD cord-005646-xhx9pzhj 2251 3 hours hour NNS cord-005646-xhx9pzhj 2251 4 weaning weaning NN cord-005646-xhx9pzhj 2251 5 begun begin VBN cord-005646-xhx9pzhj 2251 6 ~ ~ NFP cord-005646-xhx9pzhj 2251 7 and and CC cord-005646-xhx9pzhj 2251 8 the the DT cord-005646-xhx9pzhj 2251 9 same same JJ cord-005646-xhx9pzhj 2251 10 episode episode NN cord-005646-xhx9pzhj 2251 11 w w NNP cord-005646-xhx9pzhj 2251 12 ~ ~ NFP cord-005646-xhx9pzhj 2251 13 as as IN cord-005646-xhx9pzhj 2251 14 seen see VBN cord-005646-xhx9pzhj 2251 15 . . . cord-005646-xhx9pzhj 2252 1 At at IN cord-005646-xhx9pzhj 2252 2 this this DT cord-005646-xhx9pzhj 2252 3 point point NN cord-005646-xhx9pzhj 2252 4 her -PRON- PRP$ cord-005646-xhx9pzhj 2252 5 mother mother NN cord-005646-xhx9pzhj 2252 6 stated state VBD cord-005646-xhx9pzhj 2252 7 that that IN cord-005646-xhx9pzhj 2252 8 the the DT cord-005646-xhx9pzhj 2252 9 girl girl NN cord-005646-xhx9pzhj 2252 10 showed show VBD cord-005646-xhx9pzhj 2252 11 weakness weakness NN cord-005646-xhx9pzhj 2252 12 of of IN cord-005646-xhx9pzhj 2252 13 the the DT cord-005646-xhx9pzhj 2252 14 eyelids eyelid NNS cord-005646-xhx9pzhj 2252 15 or or CC cord-005646-xhx9pzhj 2252 16 extraneular extraneular JJ cord-005646-xhx9pzhj 2252 17 muscles muscle NNS cord-005646-xhx9pzhj 2252 18 . . . cord-005646-xhx9pzhj 2253 1 It -PRON- PRP cord-005646-xhx9pzhj 2253 2 suggested suggest VBD cord-005646-xhx9pzhj 2253 3 myasthenic myasthenic JJ cord-005646-xhx9pzhj 2253 4 syndrome syndrome NN cord-005646-xhx9pzhj 2253 5 vs vs IN cord-005646-xhx9pzhj 2253 6 ~-Barr6 ~-barr6 CD cord-005646-xhx9pzhj 2253 7 syndrome syndrome NN cord-005646-xhx9pzhj 2253 8 . . . cord-005646-xhx9pzhj 2254 1 C. C. NNP cord-005646-xhx9pzhj 2254 2 botul#num botul#num IN cord-005646-xhx9pzhj 2254 3 toxins toxin NNS cord-005646-xhx9pzhj 2254 4 were be VBD cord-005646-xhx9pzhj 2254 5 negative negative JJ cord-005646-xhx9pzhj 2254 6 , , , cord-005646-xhx9pzhj 2254 7 chotinesterase chotinesterase NN cord-005646-xhx9pzhj 2254 8 level level NN cord-005646-xhx9pzhj 2254 9 ~as ~as NNP cord-005646-xhx9pzhj 2254 10 normal normal JJ cord-005646-xhx9pzhj 2254 11 . . . cord-005646-xhx9pzhj 2255 1 Edrofoinum Edrofoinum NNP cord-005646-xhx9pzhj 2255 2 test test NN cord-005646-xhx9pzhj 2255 3 ~as ~as NNP cord-005646-xhx9pzhj 2255 4 positive positive JJ cord-005646-xhx9pzhj 2255 5 . . . cord-005646-xhx9pzhj 2256 1 Anti anti JJ cord-005646-xhx9pzhj 2256 2 - - JJ cord-005646-xhx9pzhj 2256 3 acetyleholine acetyleholine JJ cord-005646-xhx9pzhj 2256 4 receptor receptor NN cord-005646-xhx9pzhj 2256 5 antibodies antibody NNS cord-005646-xhx9pzhj 2256 6 were be VBD cord-005646-xhx9pzhj 2256 7 negatives negative NNS cord-005646-xhx9pzhj 2256 8 . . . cord-005646-xhx9pzhj 2257 1 E.M.G. E.M.G. NNP cord-005646-xhx9pzhj 2257 2 confirmed confirm VBD cord-005646-xhx9pzhj 2257 3 MYASTHENIA MYASTHENIA NNP cord-005646-xhx9pzhj 2257 4 GRAVIS GRAVIS NNP cord-005646-xhx9pzhj 2257 5 ( ( -LRB- cord-005646-xhx9pzhj 2257 6 CONGENITAL CONGENITAL NNP cord-005646-xhx9pzhj 2257 7 vs vs IN cord-005646-xhx9pzhj 2257 8 JUVENILE juvenile JJ cord-005646-xhx9pzhj 2257 9 serenegative serenegative NN cord-005646-xhx9pzhj 2257 10 ) ) -RRB- cord-005646-xhx9pzhj 2257 11 . . . cord-005646-xhx9pzhj 2258 1 Pyridostigmine Pyridostigmine NNP cord-005646-xhx9pzhj 2258 2 was be VBD cord-005646-xhx9pzhj 2258 3 begun begin VBN cord-005646-xhx9pzhj 2258 4 and and CC cord-005646-xhx9pzhj 2258 5 the the DT cord-005646-xhx9pzhj 2258 6 trachea trachea NN cord-005646-xhx9pzhj 2258 7 was be VBD cord-005646-xhx9pzhj 2258 8 extubated extubate VBN cord-005646-xhx9pzhj 2258 9 without without IN cord-005646-xhx9pzhj 2258 10 complications complication NNS cord-005646-xhx9pzhj 2258 11 . . . cord-005646-xhx9pzhj 2259 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 2259 2 : : : cord-005646-xhx9pzhj 2260 1 Din Din NNP cord-005646-xhx9pzhj 2260 2 the the DT cord-005646-xhx9pzhj 2260 3 differential differential JJ cord-005646-xhx9pzhj 2260 4 diagnosis diagnosis NN cord-005646-xhx9pzhj 2260 5 of of IN cord-005646-xhx9pzhj 2260 6 weamng weamng NNP cord-005646-xhx9pzhj 2260 7 failure failure NN cord-005646-xhx9pzhj 2261 1 we -PRON- PRP cord-005646-xhx9pzhj 2261 2 must must MD cord-005646-xhx9pzhj 2261 3 consider consider VB cord-005646-xhx9pzhj 2262 1 ~c ~c NFP cord-005646-xhx9pzhj 2262 2 gravis~ gravis~ NNP cord-005646-xhx9pzhj 2263 1 2)Myasthenia 2)myasthenia CD cord-005646-xhx9pzhj 2264 1 Gravis Gravis NNP cord-005646-xhx9pzhj 2264 2 could could MD cord-005646-xhx9pzhj 2264 3 resemble resemble VB cord-005646-xhx9pzhj 2264 4 encephalitis encephalitis RB cord-005646-xhx9pzhj 2264 5 , , , cord-005646-xhx9pzhj 2264 6 because because IN cord-005646-xhx9pzhj 2264 7 of of IN cord-005646-xhx9pzhj 2264 8 low low JJ cord-005646-xhx9pzhj 2264 9 OCS OCS NNP cord-005646-xhx9pzhj 2264 10 , , , cord-005646-xhx9pzhj 2264 11 overall overall JJ cord-005646-xhx9pzhj 2264 12 if if IN cord-005646-xhx9pzhj 2264 13 is be VBZ cord-005646-xhx9pzhj 2264 14 triggered trigger VBN cord-005646-xhx9pzhj 2264 15 by by IN cord-005646-xhx9pzhj 2264 16 viral viral JJ cord-005646-xhx9pzhj 2264 17 infection infection NN cord-005646-xhx9pzhj 2264 18 . . . cord-005646-xhx9pzhj 2265 1 3)In 3)in CD cord-005646-xhx9pzhj 2265 2 some some DT cord-005646-xhx9pzhj 2265 3 diseases disease NNS cord-005646-xhx9pzhj 2265 4 ( ( -LRB- cord-005646-xhx9pzhj 2265 5 this this DT cord-005646-xhx9pzhj 2265 6 case case NN cord-005646-xhx9pzhj 2265 7 ) ) -RRB- cord-005646-xhx9pzhj 2265 8 GCS GCS NNP cord-005646-xhx9pzhj 2266 1 could could MD cord-005646-xhx9pzhj 2266 2 not not RB cord-005646-xhx9pzhj 2266 3 he -PRON- PRP cord-005646-xhx9pzhj 2266 4 an an DT cord-005646-xhx9pzhj 2266 5 aemuate aemuate NNP cord-005646-xhx9pzhj 2266 6 index index NN cord-005646-xhx9pzhj 2266 7 of of IN cord-005646-xhx9pzhj 2266 8 mental mental JJ cord-005646-xhx9pzhj 2266 9 state state NN cord-005646-xhx9pzhj 2266 10 . . . cord-005646-xhx9pzhj 2267 1 A a DT cord-005646-xhx9pzhj 2267 2 BURGUET BURGUET NNP cord-005646-xhx9pzhj 2267 3 * * NFP cord-005646-xhx9pzhj 2267 4 , , , cord-005646-xhx9pzhj 2267 5 A a DT cord-005646-xhx9pzhj 2267 6 MENGET MENGET NNP cord-005646-xhx9pzhj 2267 7 * * NFP cord-005646-xhx9pzhj 2267 8 , , , cord-005646-xhx9pzhj 2267 9 E e NN cord-005646-xhx9pzhj 2267 10 MONNET MONNET NNS cord-005646-xhx9pzhj 2268 1 * * NFP cord-005646-xhx9pzhj 2268 2 * * NFP cord-005646-xhx9pzhj 2268 3 , , , cord-005646-xhx9pzhj 2268 4 A a DT cord-005646-xhx9pzhj 2268 5 GASCA GASCA NNP cord-005646-xhx9pzhj 2268 6 - - HYPH cord-005646-xhx9pzhj 2268 7 AVANZI AVANZI NNP cord-005646-xhx9pzhj 2269 1 * * NFP cord-005646-xhx9pzhj 2269 2 , , , cord-005646-xhx9pzhj 2269 3 C C NNP cord-005646-xhx9pzhj 2269 4 FROMENTIN FROMENTIN NNP cord-005646-xhx9pzhj 2270 1 * * NFP cord-005646-xhx9pzhj 2270 2 , , , cord-005646-xhx9pzhj 2270 3 H H NNP cord-005646-xhx9pzhj 2270 4 ALLEMAND ALLEMAND NNP cord-005646-xhx9pzhj 2271 1 * * NFP cord-005646-xhx9pzhj 2271 2 * * NFP cord-005646-xhx9pzhj 2271 3 , , , cord-005646-xhx9pzhj 2271 4 JY JY NNP cord-005646-xhx9pzhj 2271 5 PAUCHARD PAUCHARD NNP cord-005646-xhx9pzhj 2272 1 * * NFP cord-005646-xhx9pzhj 2272 2 , , , cord-005646-xhx9pzhj 2272 3 ML ML NNP cord-005646-xhx9pzhj 2272 4 DALPHIN DALPHIN NNP cord-005646-xhx9pzhj 2273 1 * * NFP cord-005646-xhx9pzhj 2273 2 . . . cord-005646-xhx9pzhj 2274 1 * * NFP cord-005646-xhx9pzhj 2274 2 R4animation R4animation . cord-005646-xhx9pzhj 2275 1 Infantile infantile JJ cord-005646-xhx9pzhj 2275 2 Potyvaiente Potyvaiente NNP cord-005646-xhx9pzhj 2275 3 CHU CHU NNP cord-005646-xhx9pzhj 2276 1 St St NNP cord-005646-xhx9pzhj 2276 2 JACQUES JACQUES NNP cord-005646-xhx9pzhj 2276 3 25030 25030 CD cord-005646-xhx9pzhj 2276 4 BESANCON BESANCON NNP cord-005646-xhx9pzhj 2276 5 Cedex Cedex NNP cord-005646-xhx9pzhj 2276 6 . . . cord-005646-xhx9pzhj 2277 1 * * NFP cord-005646-xhx9pzhj 2277 2 * * NFP cord-005646-xhx9pzhj 2277 3 D D NNP cord-005646-xhx9pzhj 2277 4 ~ ~ NNP cord-005646-xhx9pzhj 2277 5 padement padement NN cord-005646-xhx9pzhj 2277 6 de de FW cord-005646-xhx9pzhj 2277 7 Sant6 Sant6 NNP cord-005646-xhx9pzhj 2277 8 Publique Publique NNP cord-005646-xhx9pzhj 2277 9 25030 25030 CD cord-005646-xhx9pzhj 2277 10 BESANCON BESANCON NNP cord-005646-xhx9pzhj 2277 11 Cedex Cedex NNP cord-005646-xhx9pzhj 2277 12 , , , cord-005646-xhx9pzhj 2277 13 FRANCE FRANCE NNP cord-005646-xhx9pzhj 2277 14 , , , cord-005646-xhx9pzhj 2277 15 Objective Objective NNP cord-005646-xhx9pzhj 2277 16 : : : cord-005646-xhx9pzhj 2278 1 to to TO cord-005646-xhx9pzhj 2278 2 point point VB cord-005646-xhx9pzhj 2278 3 out out RP cord-005646-xhx9pzhj 2278 4 that that IN cord-005646-xhx9pzhj 2278 5 strabism strabism NN cord-005646-xhx9pzhj 2278 6 iS be VBZ cord-005646-xhx9pzhj 2278 7 ) ) -RRB- cord-005646-xhx9pzhj 2278 8 of of IN cord-005646-xhx9pzhj 2278 9 one one CD cord-005646-xhx9pzhj 2278 10 - - HYPH cord-005646-xhx9pzhj 2278 11 year year NN cord-005646-xhx9pzhj 2278 12 - - HYPH cord-005646-xhx9pzhj 2278 13 old old JJ cord-005646-xhx9pzhj 2278 14 premature premature JJ cord-005646-xhx9pzhj 2278 15 is be VBZ cord-005646-xhx9pzhj 2278 16 a a DT cord-005646-xhx9pzhj 2278 17 good good JJ cord-005646-xhx9pzhj 2278 18 predictor predictor NN cord-005646-xhx9pzhj 2278 19 of of IN cord-005646-xhx9pzhj 2278 20 a a DT cord-005646-xhx9pzhj 2278 21 poor poor JJ cord-005646-xhx9pzhj 2278 22 neurological neurological JJ cord-005646-xhx9pzhj 2278 23 outcome outcome NN cord-005646-xhx9pzhj 2278 24 at at IN cord-005646-xhx9pzhj 2278 25 two two CD cord-005646-xhx9pzhj 2278 26 years year NNS cord-005646-xhx9pzhj 2278 27 of of IN cord-005646-xhx9pzhj 2278 28 age age NN cord-005646-xhx9pzhj 2278 29 . . . cord-005646-xhx9pzhj 2279 1 Design design NN cord-005646-xhx9pzhj 2279 2 and and CC cord-005646-xhx9pzhj 2279 3 setting setting NN cord-005646-xhx9pzhj 2279 4 : : : cord-005646-xhx9pzhj 2279 5 two two CD cord-005646-xhx9pzhj 2279 6 - - HYPH cord-005646-xhx9pzhj 2279 7 year year NN cord-005646-xhx9pzhj 2279 8 prospective prospective JJ cord-005646-xhx9pzhj 2279 9 cohort cohort NN cord-005646-xhx9pzhj 2279 10 study study NN cord-005646-xhx9pzhj 2279 11 and and CC cord-005646-xhx9pzhj 2279 12 geographically geographically RB cord-005646-xhx9pzhj 2279 13 defined define VBN cord-005646-xhx9pzhj 2279 14 study study NN cord-005646-xhx9pzhj 2279 15 ( ( -LRB- cord-005646-xhx9pzhj 2279 16 region region NN cord-005646-xhx9pzhj 2279 17 of of IN cord-005646-xhx9pzhj 2279 18 Franche Franche NNP cord-005646-xhx9pzhj 2279 19 - - HYPH cord-005646-xhx9pzhj 2279 20 Comte Comte NNP cord-005646-xhx9pzhj 2279 21 , , , cord-005646-xhx9pzhj 2279 22 FRANCE FRANCE NNP cord-005646-xhx9pzhj 2279 23 ) ) -RRB- cord-005646-xhx9pzhj 2279 24 . . . cord-005646-xhx9pzhj 2280 1 Main main JJ cord-005646-xhx9pzhj 2280 2 outcome outcome NN cord-005646-xhx9pzhj 2280 3 measures measure NNS cord-005646-xhx9pzhj 2280 4 : : : cord-005646-xhx9pzhj 2281 1 neurological neurological JJ cord-005646-xhx9pzhj 2281 2 assessment assessment NN cord-005646-xhx9pzhj 2281 3 was be VBD cord-005646-xhx9pzhj 2281 4 performed perform VBN cord-005646-xhx9pzhj 2281 5 at at IN cord-005646-xhx9pzhj 2281 6 one one CD cord-005646-xhx9pzhj 2281 7 and and CC cord-005646-xhx9pzhj 2281 8 two two CD cord-005646-xhx9pzhj 2281 9 years year NNS cord-005646-xhx9pzhj 2281 10 of of IN cord-005646-xhx9pzhj 2281 11 age age NN cord-005646-xhx9pzhj 2281 12 ( ( -LRB- cord-005646-xhx9pzhj 2281 13 uncorrected uncorrecte VBN cord-005646-xhx9pzhj 2281 14 for for IN cord-005646-xhx9pzhj 2281 15 gestationnal gestationnal JJ cord-005646-xhx9pzhj 2281 16 age age NNP cord-005646-xhx9pzhj 2281 17 ) ) -RRB- cord-005646-xhx9pzhj 2281 18 . . . cord-005646-xhx9pzhj 2282 1 A a DT cord-005646-xhx9pzhj 2282 2 mailing mailing NN cord-005646-xhx9pzhj 2282 3 questionnaire questionnaire NN cord-005646-xhx9pzhj 2282 4 was be VBD cord-005646-xhx9pzhj 2282 5 sent send VBN cord-005646-xhx9pzhj 2282 6 to to IN cord-005646-xhx9pzhj 2282 7 the the DT cord-005646-xhx9pzhj 2282 8 famity famity NN cord-005646-xhx9pzhj 2282 9 and and CC cord-005646-xhx9pzhj 2282 10 fuU fuu NN cord-005646-xhx9pzhj 2282 11 - - HYPH cord-005646-xhx9pzhj 2282 12 filled fill VBN cord-005646-xhx9pzhj 2282 13 by by IN cord-005646-xhx9pzhj 2282 14 thefamily thefamily NNP cord-005646-xhx9pzhj 2282 15 doctor doctor NNP cord-005646-xhx9pzhj 2282 16 ( ( -LRB- cord-005646-xhx9pzhj 2282 17 pediatrician pediatrician NN cord-005646-xhx9pzhj 2282 18 or or CC cord-005646-xhx9pzhj 2282 19 physician physician NN cord-005646-xhx9pzhj 2282 20 ) ) -RRB- cord-005646-xhx9pzhj 2282 21 , , , cord-005646-xhx9pzhj 2282 22 or or CC cord-005646-xhx9pzhj 2282 23 neonatologist neonatologist NN cord-005646-xhx9pzhj 2282 24 of of IN cord-005646-xhx9pzhj 2282 25 the the DT cord-005646-xhx9pzhj 2282 26 ICU ICU NNP cord-005646-xhx9pzhj 2282 27 at at IN cord-005646-xhx9pzhj 2282 28 tertiary tertiary JJ cord-005646-xhx9pzhj 2282 29 center center NN cord-005646-xhx9pzhj 2282 30 , , , cord-005646-xhx9pzhj 2282 31 S S NNP cord-005646-xhx9pzhj 2282 32 was be VBD cord-005646-xhx9pzhj 2282 33 diagnosed diagnose VBN cord-005646-xhx9pzhj 2282 34 at at IN cord-005646-xhx9pzhj 2282 35 one one CD cord-005646-xhx9pzhj 2282 36 year year NN cord-005646-xhx9pzhj 2282 37 of of IN cord-005646-xhx9pzhj 2282 38 age age NN cord-005646-xhx9pzhj 2282 39 by by IN cord-005646-xhx9pzhj 2282 40 the the DT cord-005646-xhx9pzhj 2282 41 examinator examinator NN cord-005646-xhx9pzhj 2283 1 but but CC cord-005646-xhx9pzhj 2283 2 S S NNP cord-005646-xhx9pzhj 2283 3 was be VBD cord-005646-xhx9pzhj 2283 4 not not RB cord-005646-xhx9pzhj 2283 5 used use VBN cord-005646-xhx9pzhj 2283 6 to to TO cord-005646-xhx9pzhj 2283 7 diagnose diagnose VB cord-005646-xhx9pzhj 2283 8 cerebral cerebral JJ cord-005646-xhx9pzhj 2283 9 palsy palsy NN cord-005646-xhx9pzhj 2283 10 ( ( -LRB- cord-005646-xhx9pzhj 2283 11 CP CP NNP cord-005646-xhx9pzhj 2283 12 ) ) -RRB- cord-005646-xhx9pzhj 2283 13 . . . cord-005646-xhx9pzhj 2284 1 Sample sample NN cord-005646-xhx9pzhj 2284 2 : : : cord-005646-xhx9pzhj 2284 3 161 161 CD cord-005646-xhx9pzhj 2284 4 of of IN cord-005646-xhx9pzhj 2284 5 171 171 CD cord-005646-xhx9pzhj 2284 6 survivors survivor NNS cord-005646-xhx9pzhj 2284 7 ( ( -LRB- cord-005646-xhx9pzhj 2284 8 94 94 CD cord-005646-xhx9pzhj 2284 9 % % NN cord-005646-xhx9pzhj 2284 10 ) ) -RRB- cord-005646-xhx9pzhj 2284 11 evaluated evaluate VBN cord-005646-xhx9pzhj 2284 12 at at IN cord-005646-xhx9pzhj 2284 13 one one CD cord-005646-xhx9pzhj 2284 14 and and CC cord-005646-xhx9pzhj 2284 15 two two CD cord-005646-xhx9pzhj 2284 16 years year NNS cord-005646-xhx9pzhj 2284 17 of of IN cord-005646-xhx9pzhj 2284 18 age age NN cord-005646-xhx9pzhj 2284 19 . . . cord-005646-xhx9pzhj 2285 1 Results result NNS cord-005646-xhx9pzhj 2285 2 : : : cord-005646-xhx9pzhj 2285 3 correlation correlation NN cord-005646-xhx9pzhj 2285 4 of of IN cord-005646-xhx9pzhj 2285 5 one one CD cord-005646-xhx9pzhj 2285 6 and and CC cord-005646-xhx9pzhj 2285 7 two two CD cord-005646-xhx9pzhj 2285 8 years year NNS cord-005646-xhx9pzhj 2286 1 neurological neurological JJ cord-005646-xhx9pzhj 2286 2 evaluation evaluation NN cord-005646-xhx9pzhj 2286 3 is be VBZ cord-005646-xhx9pzhj 2286 4 weak weak JJ cord-005646-xhx9pzhj 2286 5 ( ( -LRB- cord-005646-xhx9pzhj 2286 6 kappa=0.5 kappa=0.5 NNP cord-005646-xhx9pzhj 2286 7 ) ) -RRB- cord-005646-xhx9pzhj 2286 8 . . . cord-005646-xhx9pzhj 2287 1 Correlation correlation NN cord-005646-xhx9pzhj 2287 2 of of IN cord-005646-xhx9pzhj 2287 3 S S NNP cord-005646-xhx9pzhj 2287 4 at at IN cord-005646-xhx9pzhj 2287 5 one one CD cord-005646-xhx9pzhj 2287 6 year year NN cord-005646-xhx9pzhj 2287 7 and and CC cord-005646-xhx9pzhj 2287 8 CP cp NN cord-005646-xhx9pzhj 2287 9 at at IN cord-005646-xhx9pzhj 2287 10 two two CD cord-005646-xhx9pzhj 2287 11 year year NN cord-005646-xhx9pzhj 2287 12 is be VBZ cord-005646-xhx9pzhj 2287 13 fair fair JJ cord-005646-xhx9pzhj 2287 14 ( ( -LRB- cord-005646-xhx9pzhj 2287 15 kappa=0,72 kappa=0,72 NNP cord-005646-xhx9pzhj 2287 16 ) ) -RRB- cord-005646-xhx9pzhj 2287 17 . . . cord-005646-xhx9pzhj 2288 1 The the DT cord-005646-xhx9pzhj 2288 2 goal goal NN cord-005646-xhx9pzhj 2288 3 of of IN cord-005646-xhx9pzhj 2288 4 this this DT cord-005646-xhx9pzhj 2288 5 paper paper NN cord-005646-xhx9pzhj 2288 6 is be VBZ cord-005646-xhx9pzhj 2288 7 to to TO cord-005646-xhx9pzhj 2288 8 review review VB cord-005646-xhx9pzhj 2288 9 evidence evidence NN cord-005646-xhx9pzhj 2288 10 related relate VBN cord-005646-xhx9pzhj 2288 11 to to IN cord-005646-xhx9pzhj 2288 12 hypothesis hypothesis NN cord-005646-xhx9pzhj 2288 13 that that IN cord-005646-xhx9pzhj 2288 14 the the DT cord-005646-xhx9pzhj 2288 15 " " `` cord-005646-xhx9pzhj 2288 16 waiting wait VBG cord-005646-xhx9pzhj 2288 17 " " '' cord-005646-xhx9pzhj 2288 18 axons axon NNS cord-005646-xhx9pzhj 2288 19 and and CC cord-005646-xhx9pzhj 2288 20 cells cell NNS cord-005646-xhx9pzhj 2288 21 of of IN cord-005646-xhx9pzhj 2288 22 the the DT cord-005646-xhx9pzhj 2288 23 transient transient JJ cord-005646-xhx9pzhj 2288 24 subplate subplate NN cord-005646-xhx9pzhj 2288 25 zone zone NN cord-005646-xhx9pzhj 2288 26 may may MD cord-005646-xhx9pzhj 2288 27 participate participate VB cord-005646-xhx9pzhj 2288 28 in in IN cord-005646-xhx9pzhj 2288 29 the the DT cord-005646-xhx9pzhj 2288 30 structural structural JJ cord-005646-xhx9pzhj 2288 31 plasticity plasticity NN cord-005646-xhx9pzhj 2288 32 of of IN cord-005646-xhx9pzhj 2288 33 the the DT cord-005646-xhx9pzhj 2288 34 human human JJ cord-005646-xhx9pzhj 2288 35 cerebral cerebral JJ cord-005646-xhx9pzhj 2288 36 cortex cortex NN cord-005646-xhx9pzhj 2288 37 after after IN cord-005646-xhx9pzhj 2288 38 perinataI perinataI NNP cord-005646-xhx9pzhj 2288 39 brain brain NN cord-005646-xhx9pzhj 2288 40 damage damage NN cord-005646-xhx9pzhj 2288 41 ( ( -LRB- cord-005646-xhx9pzhj 2288 42 Kostovic Kostovic NNP cord-005646-xhx9pzhj 2288 43 et et NNP cord-005646-xhx9pzhj 2288 44 aL aL NNP cord-005646-xhx9pzhj 2288 45 , , , cord-005646-xhx9pzhj 2288 46 Metabot Metabot NNP cord-005646-xhx9pzhj 2288 47 Brain Brain NNP cord-005646-xhx9pzhj 2288 48 Res4:17 Res4:17 NNP cord-005646-xhx9pzhj 2288 49 , , , cord-005646-xhx9pzhj 2288 50 t989 t989 NNP cord-005646-xhx9pzhj 2288 51 ) ) -RRB- cord-005646-xhx9pzhj 2288 52 and and CC cord-005646-xhx9pzhj 2288 53 to to TO cord-005646-xhx9pzhj 2288 54 correlate correlate VB cord-005646-xhx9pzhj 2288 55 this this DT cord-005646-xhx9pzhj 2288 56 phenomenon phenomenon NN cord-005646-xhx9pzhj 2288 57 with with IN cord-005646-xhx9pzhj 2288 58 different different JJ cord-005646-xhx9pzhj 2288 59 forms form NNS cord-005646-xhx9pzhj 2288 60 and and CC cord-005646-xhx9pzhj 2288 61 mechanisms mechanism NNS cord-005646-xhx9pzhj 2288 62 of of IN cord-005646-xhx9pzhj 2288 63 structural structural JJ cord-005646-xhx9pzhj 2288 64 plasticity plasticity NN cord-005646-xhx9pzhj 2288 65 . . . cord-005646-xhx9pzhj 2289 1 It -PRON- PRP cord-005646-xhx9pzhj 2289 2 is be VBZ cord-005646-xhx9pzhj 2289 3 our -PRON- PRP$ cord-005646-xhx9pzhj 2289 4 basic basic JJ cord-005646-xhx9pzhj 2289 5 assumption assumption NN cord-005646-xhx9pzhj 2289 6 that that IN cord-005646-xhx9pzhj 2289 7 all all DT cord-005646-xhx9pzhj 2289 8 lesions lesion NNS cord-005646-xhx9pzhj 2289 9 occuring occur VBG cord-005646-xhx9pzhj 2289 10 during during IN cord-005646-xhx9pzhj 2289 11 cortical cortical JJ cord-005646-xhx9pzhj 2289 12 histogenesis histogenesis NN cord-005646-xhx9pzhj 2289 13 will will MD cord-005646-xhx9pzhj 2289 14 lead lead VB cord-005646-xhx9pzhj 2289 15 to to IN cord-005646-xhx9pzhj 2289 16 more more JJR cord-005646-xhx9pzhj 2289 17 or or CC cord-005646-xhx9pzhj 2289 18 less less RBR cord-005646-xhx9pzhj 2289 19 pronounced pronounce VBN cord-005646-xhx9pzhj 2289 20 structural structural JJ cord-005646-xhx9pzhj 2289 21 reorganization reorganization NN cord-005646-xhx9pzhj 2289 22 . . . cord-005646-xhx9pzhj 2290 1 Here here RB cord-005646-xhx9pzhj 2290 2 we -PRON- PRP cord-005646-xhx9pzhj 2290 3 show show VBP cord-005646-xhx9pzhj 2290 4 that that IN cord-005646-xhx9pzhj 2290 5 various various JJ cord-005646-xhx9pzhj 2290 6 components component NNS cord-005646-xhx9pzhj 2290 7 of of IN cord-005646-xhx9pzhj 2290 8 the the DT cord-005646-xhx9pzhj 2290 9 subplate subplate NNP cord-005646-xhx9pzhj 2290 10 zone zone NN cord-005646-xhx9pzhj 2290 11 participate participate VB cord-005646-xhx9pzhj 2290 12 in in IN cord-005646-xhx9pzhj 2290 13 several several JJ cord-005646-xhx9pzhj 2290 14 forms form NNS cord-005646-xhx9pzhj 2290 15 of of IN cord-005646-xhx9pzhj 2290 16 the the DT cord-005646-xhx9pzhj 2290 17 structural structural JJ cord-005646-xhx9pzhj 2290 18 " " `` cord-005646-xhx9pzhj 2290 19 plastic plastic JJ cord-005646-xhx9pzhj 2290 20 " " '' cord-005646-xhx9pzhj 2290 21 responses response NNS cord-005646-xhx9pzhj 2290 22 in in IN cord-005646-xhx9pzhj 2290 23 the the DT cord-005646-xhx9pzhj 2290 24 human human JJ cord-005646-xhx9pzhj 2290 25 cortex cortex NN cord-005646-xhx9pzhj 2290 26 : : : cord-005646-xhx9pzhj 2290 27 modification modification NN cord-005646-xhx9pzhj 2290 28 of of IN cord-005646-xhx9pzhj 2290 29 convolutional convolutional NN cord-005646-xhx9pzhj 2290 30 pattern pattern NN cord-005646-xhx9pzhj 2290 31 , , , cord-005646-xhx9pzhj 2290 32 changes change NNS cord-005646-xhx9pzhj 2290 33 in in IN cord-005646-xhx9pzhj 2290 34 size size NN cord-005646-xhx9pzhj 2290 35 of of IN cord-005646-xhx9pzhj 2290 36 cytoarchitecturat cytoarchitecturat NNP cord-005646-xhx9pzhj 2290 37 areas~ areas~ NNP cord-005646-xhx9pzhj 2290 38 columnar columnar JJ cord-005646-xhx9pzhj 2290 39 reorganization reorganization NN cord-005646-xhx9pzhj 2290 40 , , , cord-005646-xhx9pzhj 2290 41 dendritic dendritic JJ cord-005646-xhx9pzhj 2290 42 and and CC cord-005646-xhx9pzhj 2290 43 synaptic synaptic JJ cord-005646-xhx9pzhj 2290 44 plasticity plasticity NN cord-005646-xhx9pzhj 2290 45 . . . cord-005646-xhx9pzhj 2291 1 The the DT cord-005646-xhx9pzhj 2291 2 etiological etiological JJ cord-005646-xhx9pzhj 2291 3 factors factor NNS cord-005646-xhx9pzhj 2291 4 which which WDT cord-005646-xhx9pzhj 2291 5 induce induce VBP cord-005646-xhx9pzhj 2291 6 lesions lesion NNS cord-005646-xhx9pzhj 2291 7 and and CC cord-005646-xhx9pzhj 2291 8 subsequent subsequent JJ cord-005646-xhx9pzhj 2291 9 plastic plastic NN cord-005646-xhx9pzhj 2291 10 changes change NNS cord-005646-xhx9pzhj 2291 11 act act VBP cord-005646-xhx9pzhj 2291 12 via via IN cord-005646-xhx9pzhj 2291 13 the the DT cord-005646-xhx9pzhj 2291 14 following follow VBG cord-005646-xhx9pzhj 2291 15 pathogenetic pathogenetic JJ cord-005646-xhx9pzhj 2291 16 mechanisms mechanism NNS cord-005646-xhx9pzhj 2291 17 : : : cord-005646-xhx9pzhj 2292 1 * * NFP cord-005646-xhx9pzhj 2292 2 disturbances disturbance NNS cord-005646-xhx9pzhj 2292 3 of of IN cord-005646-xhx9pzhj 2292 4 radial radial JJ cord-005646-xhx9pzhj 2292 5 unit unit NN cord-005646-xhx9pzhj 2292 6 formation formation NN cord-005646-xhx9pzhj 2292 7 ( ( -LRB- cord-005646-xhx9pzhj 2292 8 Rakic Rakic NNP cord-005646-xhx9pzhj 2292 9 ) ) -RRB- cord-005646-xhx9pzhj 2292 10 ; ; : cord-005646-xhx9pzhj 2293 1 * * NFP cord-005646-xhx9pzhj 2293 2 changes change VBZ cord-005646-xhx9pzhj 2293 3 in in IN cord-005646-xhx9pzhj 2293 4 ingrowth ingrowth NN cord-005646-xhx9pzhj 2293 5 of of IN cord-005646-xhx9pzhj 2293 6 afferent afferent JJ cord-005646-xhx9pzhj 2293 7 fibres fibre NNS cord-005646-xhx9pzhj 2293 8 ; ; : cord-005646-xhx9pzhj 2294 1 * * NFP cord-005646-xhx9pzhj 2294 2 changes change VBZ cord-005646-xhx9pzhj 2294 3 in in IN cord-005646-xhx9pzhj 2294 4 the the DT cord-005646-xhx9pzhj 2294 5 rate rate NN cord-005646-xhx9pzhj 2294 6 of of IN cord-005646-xhx9pzhj 2294 7 normally normally RB cord-005646-xhx9pzhj 2294 8 occuring occur VBG cord-005646-xhx9pzhj 2294 9 reorganisational reorganisational JJ cord-005646-xhx9pzhj 2294 10 events event NNS cord-005646-xhx9pzhj 2294 11 , , , cord-005646-xhx9pzhj 2294 12 depending depend VBG cord-005646-xhx9pzhj 2294 13 on on IN cord-005646-xhx9pzhj 2294 14 the the DT cord-005646-xhx9pzhj 2294 15 critical critical JJ cord-005646-xhx9pzhj 2294 16 period period NN cord-005646-xhx9pzhj 2294 17 for for IN cord-005646-xhx9pzhj 2294 18 a a DT cord-005646-xhx9pzhj 2294 19 given give VBN cord-005646-xhx9pzhj 2294 20 histogenetic histogenetic JJ cord-005646-xhx9pzhj 2294 21 event event NN cord-005646-xhx9pzhj 2294 22 . . . cord-005646-xhx9pzhj 2295 1 In in IN cord-005646-xhx9pzhj 2295 2 the the DT cord-005646-xhx9pzhj 2295 3 present present JJ cord-005646-xhx9pzhj 2295 4 study study NN cord-005646-xhx9pzhj 2295 5 developmental developmental JJ cord-005646-xhx9pzhj 2295 6 lesions lesion NNS cord-005646-xhx9pzhj 2295 7 ( ( -LRB- cord-005646-xhx9pzhj 2295 8 localized localize VBN cord-005646-xhx9pzhj 2295 9 perlventricular perlventricular JJ cord-005646-xhx9pzhj 2295 10 leukomalacia leukomalacia NNS cord-005646-xhx9pzhj 2295 11 and and CC cord-005646-xhx9pzhj 2295 12 haemorrhages haemorrhage NNS cord-005646-xhx9pzhj 2295 13 ) ) -RRB- cord-005646-xhx9pzhj 2295 14 were be VBD cord-005646-xhx9pzhj 2295 15 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2295 16 by by IN cord-005646-xhx9pzhj 2295 17 ultrasound ultrasound NN cord-005646-xhx9pzhj 2295 18 in in IN cord-005646-xhx9pzhj 2295 19 live live NN cord-005646-xhx9pzhj 2295 20 - - HYPH cord-005646-xhx9pzhj 2295 21 born bear VBN cord-005646-xhx9pzhj 2295 22 infants infant NNS cord-005646-xhx9pzhj 2295 23 ranging range VBG cord-005646-xhx9pzhj 2295 24 between between IN cord-005646-xhx9pzhj 2295 25 26 26 CD cord-005646-xhx9pzhj 2295 26 to to TO cord-005646-xhx9pzhj 2295 27 40 40 CD cord-005646-xhx9pzhj 2295 28 weeks week NNS cord-005646-xhx9pzhj 2295 29 of of IN cord-005646-xhx9pzhj 2295 30 gestation gestation NN cord-005646-xhx9pzhj 2295 31 . . . cord-005646-xhx9pzhj 2296 1 In in IN cord-005646-xhx9pzhj 2296 2 younger young JJR cord-005646-xhx9pzhj 2296 3 infants infant NNS cord-005646-xhx9pzhj 2296 4 ( ( -LRB- cord-005646-xhx9pzhj 2296 5 24 24 CD cord-005646-xhx9pzhj 2296 6 - - SYM cord-005646-xhx9pzhj 2296 7 34 34 CD cord-005646-xhx9pzhj 2296 8 w w NN cord-005646-xhx9pzhj 2296 9 ) ) -RRB- cord-005646-xhx9pzhj 2296 10 who who WP cord-005646-xhx9pzhj 2296 11 died die VBD cord-005646-xhx9pzhj 2296 12 shortly shortly RB cord-005646-xhx9pzhj 2296 13 after after IN cord-005646-xhx9pzhj 2296 14 birth birth NN cord-005646-xhx9pzhj 2296 15 , , , cord-005646-xhx9pzhj 2296 16 examination examination NN cord-005646-xhx9pzhj 2296 17 revealed reveal VBD cord-005646-xhx9pzhj 2296 18 lesions lesion NNS cord-005646-xhx9pzhj 2296 19 of of IN cord-005646-xhx9pzhj 2296 20 the the DT cord-005646-xhx9pzhj 2296 21 white white JJ cord-005646-xhx9pzhj 2296 22 matter matter NN cord-005646-xhx9pzhj 2296 23 with with IN cord-005646-xhx9pzhj 2296 24 the the DT cord-005646-xhx9pzhj 2296 25 preservation preservation NN cord-005646-xhx9pzhj 2296 26 of of IN cord-005646-xhx9pzhj 2296 27 the the DT cord-005646-xhx9pzhj 2296 28 subplate subplate NNP cord-005646-xhx9pzhj 2296 29 zone zone NN cord-005646-xhx9pzhj 2296 30 . . . cord-005646-xhx9pzhj 2297 1 In in IN cord-005646-xhx9pzhj 2297 2 infants infant NNS cord-005646-xhx9pzhj 2297 3 who who WP cord-005646-xhx9pzhj 2297 4 died die VBD cord-005646-xhx9pzhj 2297 5 one one CD cord-005646-xhx9pzhj 2297 6 week week NN cord-005646-xhx9pzhj 2297 7 of of IN cord-005646-xhx9pzhj 2297 8 more more JJR cord-005646-xhx9pzhj 2297 9 after after IN cord-005646-xhx9pzhj 2297 10 the the DT cord-005646-xhx9pzhj 2297 11 lesion lesion NN cord-005646-xhx9pzhj 2297 12 , , , cord-005646-xhx9pzhj 2297 13 we -PRON- PRP cord-005646-xhx9pzhj 2297 14 have have VBP cord-005646-xhx9pzhj 2297 15 observed observe VBN cord-005646-xhx9pzhj 2297 16 localized localize VBN cord-005646-xhx9pzhj 2297 17 micropolygyria micropolygyria NN cord-005646-xhx9pzhj 2297 18 , , , cord-005646-xhx9pzhj 2297 19 cavities cavity NNS cord-005646-xhx9pzhj 2297 20 , , , cord-005646-xhx9pzhj 2297 21 condensed condense VBN cord-005646-xhx9pzhj 2297 22 layer layer NN cord-005646-xhx9pzhj 2297 23 VI VI NNP cord-005646-xhx9pzhj 2297 24 -subplate -subplate HYPH cord-005646-xhx9pzhj 2297 25 zone zone NNP cord-005646-xhx9pzhj 2297 26 , , , cord-005646-xhx9pzhj 2297 27 and and CC cord-005646-xhx9pzhj 2297 28 columnations columnation NNS cord-005646-xhx9pzhj 2297 29 of of IN cord-005646-xhx9pzhj 2297 30 the the DT cord-005646-xhx9pzhj 2297 31 cortical cortical JJ cord-005646-xhx9pzhj 2297 32 plate plate NN cord-005646-xhx9pzhj 2297 33 . . . cord-005646-xhx9pzhj 2298 1 These these DT cord-005646-xhx9pzhj 2298 2 changes change NNS cord-005646-xhx9pzhj 2298 3 are be VBP cord-005646-xhx9pzhj 2298 4 less less RBR cord-005646-xhx9pzhj 2298 5 prominent prominent JJ cord-005646-xhx9pzhj 2298 6 if if IN cord-005646-xhx9pzhj 2298 7 the the DT cord-005646-xhx9pzhj 2298 8 lesion lesion NN cord-005646-xhx9pzhj 2298 9 occurs occur VBZ cord-005646-xhx9pzhj 2298 10 after after IN cord-005646-xhx9pzhj 2298 11 diminishment diminishment NN cord-005646-xhx9pzhj 2298 12 of of IN cord-005646-xhx9pzhj 2298 13 the the DT cord-005646-xhx9pzhj 2298 14 subplate subplate NNP cord-005646-xhx9pzhj 2298 15 zone zone NN cord-005646-xhx9pzhj 2298 16 ( ( -LRB- cord-005646-xhx9pzhj 2298 17 after after IN cord-005646-xhx9pzhj 2298 18 34 34 CD cord-005646-xhx9pzhj 2298 19 w w NN cord-005646-xhx9pzhj 2298 20 ) ) -RRB- cord-005646-xhx9pzhj 2298 21 . . . cord-005646-xhx9pzhj 2299 1 Since since IN cord-005646-xhx9pzhj 2299 2 in in IN cord-005646-xhx9pzhj 2299 3 the the DT cord-005646-xhx9pzhj 2299 4 fetal fetal JJ cord-005646-xhx9pzhj 2299 5 cortex cortex NN cord-005646-xhx9pzhj 2299 6 the the DT cord-005646-xhx9pzhj 2299 7 subplate subplate NNP cord-005646-xhx9pzhj 2299 8 zone zone NN cord-005646-xhx9pzhj 2299 9 serves serve VBZ cord-005646-xhx9pzhj 2299 10 as as IN cord-005646-xhx9pzhj 2299 11 predominant predominant JJ cord-005646-xhx9pzhj 2299 12 source source NN cord-005646-xhx9pzhj 2299 13 of of IN cord-005646-xhx9pzhj 2299 14 growing grow VBG cord-005646-xhx9pzhj 2299 15 fibers fiber NNS cord-005646-xhx9pzhj 2299 16 , , , cord-005646-xhx9pzhj 2299 17 transient transient JJ cord-005646-xhx9pzhj 2299 18 neurons neuron NNS cord-005646-xhx9pzhj 2299 19 , , , cord-005646-xhx9pzhj 2299 20 trophic trophic NN cord-005646-xhx9pzhj 2299 21 factors factor NNS cord-005646-xhx9pzhj 2299 22 and and CC cord-005646-xhx9pzhj 2299 23 contains contain VBZ cord-005646-xhx9pzhj 2299 24 cellular cellular JJ cord-005646-xhx9pzhj 2299 25 substrata substrata NNS cord-005646-xhx9pzhj 2299 26 for for IN cord-005646-xhx9pzhj 2299 27 migration migration NN cord-005646-xhx9pzhj 2299 28 , , , cord-005646-xhx9pzhj 2299 29 this this DT cord-005646-xhx9pzhj 2299 30 zone zone NN cord-005646-xhx9pzhj 2299 31 is be VBZ cord-005646-xhx9pzhj 2299 32 the the DT cord-005646-xhx9pzhj 2299 33 most most RBS cord-005646-xhx9pzhj 2299 34 likely likely JJ cord-005646-xhx9pzhj 2299 35 candidate candidate NN cord-005646-xhx9pzhj 2299 36 for for IN cord-005646-xhx9pzhj 2299 37 major major JJ cord-005646-xhx9pzhj 2299 38 types type NNS cord-005646-xhx9pzhj 2299 39 of of IN cord-005646-xhx9pzhj 2299 40 structural structural JJ cord-005646-xhx9pzhj 2299 41 plasticity plasticity NN cord-005646-xhx9pzhj 2299 42 . . . cord-005646-xhx9pzhj 2300 1 In in IN cord-005646-xhx9pzhj 2300 2 conclusion conclusion NN cord-005646-xhx9pzhj 2300 3 , , , cord-005646-xhx9pzhj 2300 4 cerebral cerebral JJ cord-005646-xhx9pzhj 2300 5 cortex cortex NN cord-005646-xhx9pzhj 2300 6 of of IN cord-005646-xhx9pzhj 2300 7 the the DT cord-005646-xhx9pzhj 2300 8 low low JJ cord-005646-xhx9pzhj 2300 9 -birthweight -birthweight HYPH cord-005646-xhx9pzhj 2300 10 infants infant NNS cord-005646-xhx9pzhj 2300 11 is be VBZ cord-005646-xhx9pzhj 2300 12 more more RBR cord-005646-xhx9pzhj 2300 13 susceptible susceptible JJ cord-005646-xhx9pzhj 2300 14 to to IN cord-005646-xhx9pzhj 2300 15 the the DT cord-005646-xhx9pzhj 2300 16 various various JJ cord-005646-xhx9pzhj 2300 17 lesions lesion NNS cord-005646-xhx9pzhj 2300 18 but but CC cord-005646-xhx9pzhj 2300 19 shows show VBZ cord-005646-xhx9pzhj 2300 20 vigorous vigorous JJ cord-005646-xhx9pzhj 2300 21 structural structural JJ cord-005646-xhx9pzhj 2300 22 plasticity plasticity NN cord-005646-xhx9pzhj 2300 23 and and CC cord-005646-xhx9pzhj 2300 24 conspicuous conspicuous JJ cord-005646-xhx9pzhj 2300 25 functional functional JJ cord-005646-xhx9pzhj 2300 26 recovery recovery NN cord-005646-xhx9pzhj 2300 27 due due IN cord-005646-xhx9pzhj 2300 28 to to IN cord-005646-xhx9pzhj 2300 29 the the DT cord-005646-xhx9pzhj 2300 30 growing growing NN cord-005646-xhx9pzhj 2300 31 , , , cord-005646-xhx9pzhj 2300 32 transiently transiently RB cord-005646-xhx9pzhj 2300 33 located locate VBN cord-005646-xhx9pzhj 2300 34 neuron neuron NN cord-005646-xhx9pzhj 2300 35 at at IN cord-005646-xhx9pzhj 2300 36 elements element NNS cord-005646-xhx9pzhj 2300 37 . . . cord-005646-xhx9pzhj 2301 1 The the DT cord-005646-xhx9pzhj 2301 2 mortality mortality NN cord-005646-xhx9pzhj 2301 3 due due JJ cord-005646-xhx9pzhj 2301 4 to to IN cord-005646-xhx9pzhj 2301 5 meningoccocal meningoccocal JJ cord-005646-xhx9pzhj 2301 6 sepsis sepsis NN cord-005646-xhx9pzhj 2301 7 is be VBZ cord-005646-xhx9pzhj 2301 8 high high JJ cord-005646-xhx9pzhj 2301 9 in in IN cord-005646-xhx9pzhj 2301 10 spite spite NN cord-005646-xhx9pzhj 2301 11 of of IN cord-005646-xhx9pzhj 2301 12 important important JJ cord-005646-xhx9pzhj 2301 13 progress progress NN cord-005646-xhx9pzhj 2301 14 in in IN cord-005646-xhx9pzhj 2301 15 emergency emergency NN cord-005646-xhx9pzhj 2301 16 and and CC cord-005646-xhx9pzhj 2301 17 intensive intensive JJ cord-005646-xhx9pzhj 2301 18 care care NN cord-005646-xhx9pzhj 2301 19 medicine medicine NN cord-005646-xhx9pzhj 2301 20 . . . cord-005646-xhx9pzhj 2302 1 During during IN cord-005646-xhx9pzhj 2302 2 the the DT cord-005646-xhx9pzhj 2302 3 last last JJ cord-005646-xhx9pzhj 2302 4 decade decade NN cord-005646-xhx9pzhj 2302 5 multiple multiple JJ cord-005646-xhx9pzhj 2302 6 scoring scoring NN cord-005646-xhx9pzhj 2302 7 - - HYPH cord-005646-xhx9pzhj 2302 8 systems system NNS cord-005646-xhx9pzhj 2302 9 have have VBP cord-005646-xhx9pzhj 2302 10 been be VBN cord-005646-xhx9pzhj 2302 11 developed develop VBN cord-005646-xhx9pzhj 2302 12 in in IN cord-005646-xhx9pzhj 2302 13 order order NN cord-005646-xhx9pzhj 2302 14 to to TO cord-005646-xhx9pzhj 2302 15 establish establish VB cord-005646-xhx9pzhj 2302 16 a a DT cord-005646-xhx9pzhj 2302 17 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2302 18 approach approach NN cord-005646-xhx9pzhj 2302 19 and and CC cord-005646-xhx9pzhj 2302 20 to to TO cord-005646-xhx9pzhj 2302 21 evaluate evaluate VB cord-005646-xhx9pzhj 2302 22 the the DT cord-005646-xhx9pzhj 2302 23 final final JJ cord-005646-xhx9pzhj 2302 24 outcome outcome NN cord-005646-xhx9pzhj 2302 25 of of IN cord-005646-xhx9pzhj 2302 26 a a DT cord-005646-xhx9pzhj 2302 27 meningococcal meningococcal JJ cord-005646-xhx9pzhj 2302 28 infection infection NN cord-005646-xhx9pzhj 2302 29 . . . cord-005646-xhx9pzhj 2303 1 Different different JJ cord-005646-xhx9pzhj 2303 2 clinical clinical JJ cord-005646-xhx9pzhj 2303 3 and and CC cord-005646-xhx9pzhj 2303 4 biological biological JJ cord-005646-xhx9pzhj 2303 5 data datum NNS cord-005646-xhx9pzhj 2303 6 ( ( -LRB- cord-005646-xhx9pzhj 2303 7 shock shock NN cord-005646-xhx9pzhj 2303 8 , , , cord-005646-xhx9pzhj 2303 9 ecchymosis ecchymosis NN cord-005646-xhx9pzhj 2303 10 , , , cord-005646-xhx9pzhj 2303 11 peripheral peripheral JJ cord-005646-xhx9pzhj 2303 12 WBC WBC NNP cord-005646-xhx9pzhj 2303 13 and and CC cord-005646-xhx9pzhj 2303 14 platelet platelet NN cord-005646-xhx9pzhj 2303 15 count count NN cord-005646-xhx9pzhj 2303 16 , , , cord-005646-xhx9pzhj 2303 17 coagulopathy coagulopathy NN cord-005646-xhx9pzhj 2303 18 , , , cord-005646-xhx9pzhj 2303 19 acidosis acidosis NN cord-005646-xhx9pzhj 2303 20 , , , cord-005646-xhx9pzhj 2303 21 meningism meningism NN cord-005646-xhx9pzhj 2303 22 , , , cord-005646-xhx9pzhj 2303 23 etc etc FW cord-005646-xhx9pzhj 2303 24 ) ) -RRB- cord-005646-xhx9pzhj 2303 25 are be VBP cord-005646-xhx9pzhj 2303 26 taken take VBN cord-005646-xhx9pzhj 2303 27 into into IN cord-005646-xhx9pzhj 2303 28 consideration consideration NN cord-005646-xhx9pzhj 2303 29 and and CC cord-005646-xhx9pzhj 2303 30 the the DT cord-005646-xhx9pzhj 2303 31 importance importance NN cord-005646-xhx9pzhj 2303 32 given give VBN cord-005646-xhx9pzhj 2303 33 to to IN cord-005646-xhx9pzhj 2303 34 these these DT cord-005646-xhx9pzhj 2303 35 data datum NNS cord-005646-xhx9pzhj 2303 36 depends depend VBZ cord-005646-xhx9pzhj 2303 37 on on IN cord-005646-xhx9pzhj 2303 38 the the DT cord-005646-xhx9pzhj 2303 39 scoring scoring NN cord-005646-xhx9pzhj 2303 40 - - HYPH cord-005646-xhx9pzhj 2303 41 system system NN cord-005646-xhx9pzhj 2303 42 used use VBN cord-005646-xhx9pzhj 2303 43 . . . cord-005646-xhx9pzhj 2304 1 A a DT cord-005646-xhx9pzhj 2304 2 review review NN cord-005646-xhx9pzhj 2304 3 of of IN cord-005646-xhx9pzhj 2304 4 the the DT cord-005646-xhx9pzhj 2304 5 different different JJ cord-005646-xhx9pzhj 2304 6 scoring scoring NN cord-005646-xhx9pzhj 2304 7 - - HYPH cord-005646-xhx9pzhj 2304 8 systems system NNS cord-005646-xhx9pzhj 2304 9 is be VBZ cord-005646-xhx9pzhj 2304 10 given give VBN cord-005646-xhx9pzhj 2304 11 and and CC cord-005646-xhx9pzhj 2304 12 a a DT cord-005646-xhx9pzhj 2304 13 clinical clinical JJ cord-005646-xhx9pzhj 2304 14 case case NN cord-005646-xhx9pzhj 2304 15 is be VBZ cord-005646-xhx9pzhj 2304 16 presented present VBN cord-005646-xhx9pzhj 2304 17 . . . cord-005646-xhx9pzhj 2305 1 We -PRON- PRP cord-005646-xhx9pzhj 2305 2 report report VBP cord-005646-xhx9pzhj 2305 3 the the DT cord-005646-xhx9pzhj 2305 4 case case NN cord-005646-xhx9pzhj 2305 5 of of IN cord-005646-xhx9pzhj 2305 6 a a DT cord-005646-xhx9pzhj 2305 7 4 4 CD cord-005646-xhx9pzhj 2305 8 year year NN cord-005646-xhx9pzhj 2305 9 old old JJ cord-005646-xhx9pzhj 2305 10 male male NN cord-005646-xhx9pzhj 2305 11 , , , cord-005646-xhx9pzhj 2305 12 who who WP cord-005646-xhx9pzhj 2305 13 was be VBD cord-005646-xhx9pzhj 2305 14 transfered transfer VBN cord-005646-xhx9pzhj 2305 15 to to IN cord-005646-xhx9pzhj 2305 16 our -PRON- PRP$ cord-005646-xhx9pzhj 2305 17 ICU ICU NNP cord-005646-xhx9pzhj 2305 18 12 12 CD cord-005646-xhx9pzhj 2305 19 hours hour NNS cord-005646-xhx9pzhj 2305 20 after after IN cord-005646-xhx9pzhj 2305 21 onset onset NN cord-005646-xhx9pzhj 2305 22 of of IN cord-005646-xhx9pzhj 2305 23 temperature temperature NN cord-005646-xhx9pzhj 2305 24 and and CC cord-005646-xhx9pzhj 2305 25 skin skin NN cord-005646-xhx9pzhj 2305 26 rash rash NN cord-005646-xhx9pzhj 2305 27 . . . cord-005646-xhx9pzhj 2306 1 The the DT cord-005646-xhx9pzhj 2306 2 parents parent NNS cord-005646-xhx9pzhj 2306 3 described describe VBD cord-005646-xhx9pzhj 2306 4 a a DT cord-005646-xhx9pzhj 2306 5 fast fast JJ cord-005646-xhx9pzhj 2306 6 deterioration deterioration NN cord-005646-xhx9pzhj 2306 7 of of IN cord-005646-xhx9pzhj 2306 8 his -PRON- PRP$ cord-005646-xhx9pzhj 2306 9 condition condition NN cord-005646-xhx9pzhj 2306 10 . . . cord-005646-xhx9pzhj 2307 1 The the DT cord-005646-xhx9pzhj 2307 2 boy boy NN cord-005646-xhx9pzhj 2307 3 presented present VBD cord-005646-xhx9pzhj 2307 4 wide wide JJ cord-005646-xhx9pzhj 2307 5 spread spread NN cord-005646-xhx9pzhj 2307 6 ecchymosis ecchymosis NN cord-005646-xhx9pzhj 2307 7 , , , cord-005646-xhx9pzhj 2307 8 high high JJ cord-005646-xhx9pzhj 2307 9 temperature temperature NN cord-005646-xhx9pzhj 2307 10 , , , cord-005646-xhx9pzhj 2308 1 no no DT cord-005646-xhx9pzhj 2308 2 signs sign NNS cord-005646-xhx9pzhj 2308 3 of of IN cord-005646-xhx9pzhj 2308 4 meningism meningism NN cord-005646-xhx9pzhj 2308 5 , , , cord-005646-xhx9pzhj 2308 6 circulatory circulatory JJ cord-005646-xhx9pzhj 2308 7 insufficiency insufficiency NN cord-005646-xhx9pzhj 2308 8 and and CC cord-005646-xhx9pzhj 2308 9 shock shock NN cord-005646-xhx9pzhj 2308 10 , , , cord-005646-xhx9pzhj 2308 11 coagulopathy coagulopathy NN cord-005646-xhx9pzhj 2308 12 and and CC cord-005646-xhx9pzhj 2308 13 low low JJ cord-005646-xhx9pzhj 2308 14 peripheral peripheral JJ cord-005646-xhx9pzhj 2308 15 WBC WBC NNP cord-005646-xhx9pzhj 2308 16 and and CC cord-005646-xhx9pzhj 2308 17 platetet platetet NNP cord-005646-xhx9pzhj 2308 18 count count NNP cord-005646-xhx9pzhj 2308 19 . . . cord-005646-xhx9pzhj 2309 1 Disseminated disseminate VBN cord-005646-xhx9pzhj 2309 2 intravascular intravascular JJ cord-005646-xhx9pzhj 2309 3 coagulopathy coagulopathy NN cord-005646-xhx9pzhj 2309 4 developed develop VBD cord-005646-xhx9pzhj 2309 5 promptly promptly RB cord-005646-xhx9pzhj 2309 6 . . . cord-005646-xhx9pzhj 2310 1 The the DT cord-005646-xhx9pzhj 2310 2 Glasgow Glasgow NNP cord-005646-xhx9pzhj 2310 3 Meningococcal Meningococcal NNP cord-005646-xhx9pzhj 2310 4 Septicemia septicemia NN cord-005646-xhx9pzhj 2310 5 Prognostic prognostic JJ cord-005646-xhx9pzhj 2310 6 Score score NN cord-005646-xhx9pzhj 2310 7 ( ( -LRB- cord-005646-xhx9pzhj 2310 8 GMSS GMSS NNP cord-005646-xhx9pzhj 2310 9 ) ) -RRB- cord-005646-xhx9pzhj 2310 10 was be VBD cord-005646-xhx9pzhj 2310 11 used use VBN cord-005646-xhx9pzhj 2310 12 and and CC cord-005646-xhx9pzhj 2310 13 the the DT cord-005646-xhx9pzhj 2310 14 obtained obtain VBN cord-005646-xhx9pzhj 2310 15 score score NN cord-005646-xhx9pzhj 2310 16 reached reach VBD cord-005646-xhx9pzhj 2310 17 the the DT cord-005646-xhx9pzhj 2310 18 highest high JJS cord-005646-xhx9pzhj 2310 19 level level NN cord-005646-xhx9pzhj 2310 20 ( ( -LRB- cord-005646-xhx9pzhj 2310 21 15/15 15/15 CD cord-005646-xhx9pzhj 2310 22 ) ) -RRB- cord-005646-xhx9pzhj 2310 23 . . . cord-005646-xhx9pzhj 2311 1 This this DT cord-005646-xhx9pzhj 2311 2 corresponds correspond VBZ cord-005646-xhx9pzhj 2311 3 to to IN cord-005646-xhx9pzhj 2311 4 a a DT cord-005646-xhx9pzhj 2311 5 100 100 CD cord-005646-xhx9pzhj 2311 6 % % NN cord-005646-xhx9pzhj 2311 7 mortality mortality NN cord-005646-xhx9pzhj 2311 8 . . . cord-005646-xhx9pzhj 2312 1 The the DT cord-005646-xhx9pzhj 2312 2 patient patient NN cord-005646-xhx9pzhj 2312 3 required require VBD cord-005646-xhx9pzhj 2312 4 mechanical mechanical JJ cord-005646-xhx9pzhj 2312 5 ventilation ventilation NN cord-005646-xhx9pzhj 2312 6 for for IN cord-005646-xhx9pzhj 2312 7 5 5 CD cord-005646-xhx9pzhj 2312 8 days day NNS cord-005646-xhx9pzhj 2312 9 . . . cord-005646-xhx9pzhj 2313 1 At at IN cord-005646-xhx9pzhj 2313 2 admission admission NN cord-005646-xhx9pzhj 2313 3 he -PRON- PRP cord-005646-xhx9pzhj 2313 4 received receive VBD cord-005646-xhx9pzhj 2313 5 human human JJ cord-005646-xhx9pzhj 2313 6 albumine albumine NN cord-005646-xhx9pzhj 2313 7 , , , cord-005646-xhx9pzhj 2313 8 fresh fresh JJ cord-005646-xhx9pzhj 2313 9 frozen frozen JJ cord-005646-xhx9pzhj 2313 10 plasma plasma NN cord-005646-xhx9pzhj 2313 11 , , , cord-005646-xhx9pzhj 2313 12 dexamethason dexamethason NNP cord-005646-xhx9pzhj 2313 13 , , , cord-005646-xhx9pzhj 2313 14 dopamine dopamine NN cord-005646-xhx9pzhj 2313 15 , , , cord-005646-xhx9pzhj 2313 16 dobutamine dobutamine NN cord-005646-xhx9pzhj 2313 17 and and CC cord-005646-xhx9pzhj 2313 18 a a DT cord-005646-xhx9pzhj 2313 19 continuous continuous JJ cord-005646-xhx9pzhj 2313 20 infusion infusion NN cord-005646-xhx9pzhj 2313 21 of of IN cord-005646-xhx9pzhj 2313 22 adrenaline adrenaline NN cord-005646-xhx9pzhj 2313 23 . . . cord-005646-xhx9pzhj 2314 1 Antibiotical antibiotical JJ cord-005646-xhx9pzhj 2314 2 treatment treatment NN cord-005646-xhx9pzhj 2314 3 consisted consist VBD cord-005646-xhx9pzhj 2314 4 of of IN cord-005646-xhx9pzhj 2314 5 ceftdaxone ceftdaxone NN cord-005646-xhx9pzhj 2314 6 . . . cord-005646-xhx9pzhj 2315 1 The the DT cord-005646-xhx9pzhj 2315 2 evolution evolution NN cord-005646-xhx9pzhj 2315 3 was be VBD cord-005646-xhx9pzhj 2315 4 favorable favorable JJ cord-005646-xhx9pzhj 2315 5 and and CC cord-005646-xhx9pzhj 2315 6 the the DT cord-005646-xhx9pzhj 2315 7 infant infant NN cord-005646-xhx9pzhj 2315 8 fully fully RB cord-005646-xhx9pzhj 2315 9 recovered recover VBD cord-005646-xhx9pzhj 2315 10 . . . cord-005646-xhx9pzhj 2316 1 Retrospectively retrospectively RB cord-005646-xhx9pzhj 2316 2 the the DT cord-005646-xhx9pzhj 2316 3 GMSS GMSS NNP cord-005646-xhx9pzhj 2316 4 was be VBD cord-005646-xhx9pzhj 2316 5 compared compare VBN cord-005646-xhx9pzhj 2316 6 to to IN cord-005646-xhx9pzhj 2316 7 other other JJ cord-005646-xhx9pzhj 2316 8 meningococcal meningococcal JJ cord-005646-xhx9pzhj 2316 9 scoring scoring NN cord-005646-xhx9pzhj 2316 10 scales scale NNS cord-005646-xhx9pzhj 2316 11 which which WDT cord-005646-xhx9pzhj 2316 12 gave give VBD cord-005646-xhx9pzhj 2316 13 the the DT cord-005646-xhx9pzhj 2316 14 same same JJ cord-005646-xhx9pzhj 2316 15 mortality mortality NN cord-005646-xhx9pzhj 2316 16 ( ( -LRB- cord-005646-xhx9pzhj 2316 17 100 100 CD cord-005646-xhx9pzhj 2316 18 % % NN cord-005646-xhx9pzhj 2316 19 ) ) -RRB- cord-005646-xhx9pzhj 2316 20 . . . cord-005646-xhx9pzhj 2317 1 We -PRON- PRP cord-005646-xhx9pzhj 2317 2 conclude conclude VBP cord-005646-xhx9pzhj 2317 3 that that IN cord-005646-xhx9pzhj 2317 4 the the DT cord-005646-xhx9pzhj 2317 5 scoring scoring NN cord-005646-xhx9pzhj 2317 6 - - HYPH cord-005646-xhx9pzhj 2317 7 systems system NNS cord-005646-xhx9pzhj 2317 8 are be VBP cord-005646-xhx9pzhj 2317 9 important important JJ cord-005646-xhx9pzhj 2317 10 to to TO cord-005646-xhx9pzhj 2317 11 evaluate evaluate VB cord-005646-xhx9pzhj 2317 12 the the DT cord-005646-xhx9pzhj 2317 13 seriousness seriousness NN cord-005646-xhx9pzhj 2317 14 and and CC cord-005646-xhx9pzhj 2317 15 to to TO cord-005646-xhx9pzhj 2317 16 assess assess VB cord-005646-xhx9pzhj 2317 17 the the DT cord-005646-xhx9pzhj 2317 18 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2317 19 approach approach NN cord-005646-xhx9pzhj 2317 20 , , , cord-005646-xhx9pzhj 2317 21 but but CC cord-005646-xhx9pzhj 2317 22 they -PRON- PRP cord-005646-xhx9pzhj 2317 23 should should MD cord-005646-xhx9pzhj 2317 24 be be VB cord-005646-xhx9pzhj 2317 25 used use VBN cord-005646-xhx9pzhj 2317 26 cautiously cautiously RB cord-005646-xhx9pzhj 2317 27 even even RB cord-005646-xhx9pzhj 2317 28 when when WRB cord-005646-xhx9pzhj 2317 29 100 100 CD cord-005646-xhx9pzhj 2317 30 % % NN cord-005646-xhx9pzhj 2317 31 mortality mortality NN cord-005646-xhx9pzhj 2317 32 is be VBZ cord-005646-xhx9pzhj 2317 33 predicted predict VBN cord-005646-xhx9pzhj 2317 34 by by IN cord-005646-xhx9pzhj 2317 35 several several JJ cord-005646-xhx9pzhj 2317 36 risk risk NN cord-005646-xhx9pzhj 2317 37 evaluations evaluation NNS cord-005646-xhx9pzhj 2317 38 scoring score VBG cord-005646-xhx9pzhj 2317 39 - - HYPH cord-005646-xhx9pzhj 2317 40 systems system NNS cord-005646-xhx9pzhj 2317 41 . . . cord-005646-xhx9pzhj 2318 1 The the DT cord-005646-xhx9pzhj 2318 2 aim aim NN cord-005646-xhx9pzhj 2318 3 of of IN cord-005646-xhx9pzhj 2318 4 this this DT cord-005646-xhx9pzhj 2318 5 study study NN cord-005646-xhx9pzhj 2318 6 was be VBD cord-005646-xhx9pzhj 2318 7 to to TO cord-005646-xhx9pzhj 2318 8 assess assess VB cord-005646-xhx9pzhj 2318 9 the the DT cord-005646-xhx9pzhj 2318 10 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 2318 11 status status NN cord-005646-xhx9pzhj 2318 12 on on IN cord-005646-xhx9pzhj 2318 13 admission admission NN cord-005646-xhx9pzhj 2318 14 and and CC cord-005646-xhx9pzhj 2318 15 the the DT cord-005646-xhx9pzhj 2318 16 critical critical JJ cord-005646-xhx9pzhj 2318 17 care care NN cord-005646-xhx9pzhj 2318 18 management management NN cord-005646-xhx9pzhj 2318 19 of of IN cord-005646-xhx9pzhj 2318 20 children child NNS cord-005646-xhx9pzhj 2318 21 presenting present VBG cord-005646-xhx9pzhj 2318 22 with with IN cord-005646-xhx9pzhj 2318 23 meningococcat meningococcat NN cord-005646-xhx9pzhj 2318 24 infection infection NN cord-005646-xhx9pzhj 2318 25 . . . cord-005646-xhx9pzhj 2319 1 This this DT cord-005646-xhx9pzhj 2319 2 was be VBD cord-005646-xhx9pzhj 2319 3 a a DT cord-005646-xhx9pzhj 2319 4 retrospective retrospective JJ cord-005646-xhx9pzhj 2319 5 study study NN cord-005646-xhx9pzhj 2319 6 of of IN cord-005646-xhx9pzhj 2319 7 the the DT cord-005646-xhx9pzhj 2319 8 charts chart NNS cord-005646-xhx9pzhj 2319 9 of of IN cord-005646-xhx9pzhj 2319 10 46 46 CD cord-005646-xhx9pzhj 2319 11 consecutive consecutive JJ cord-005646-xhx9pzhj 2319 12 admissions admission NNS cord-005646-xhx9pzhj 2319 13 . . . cord-005646-xhx9pzhj 2320 1 Mean mean JJ cord-005646-xhx9pzhj 2320 2 age age NN cord-005646-xhx9pzhj 2320 3 was be VBD cord-005646-xhx9pzhj 2320 4 3.43 3.43 CD cord-005646-xhx9pzhj 2320 5 years year NNS cord-005646-xhx9pzhj 2320 6 ( ( -LRB- cord-005646-xhx9pzhj 2320 7 + + CC cord-005646-xhx9pzhj 2320 8 /-3.46 /-3.46 NFP cord-005646-xhx9pzhj 2320 9 ) ) -RRB- cord-005646-xhx9pzhj 2320 10 . . . cord-005646-xhx9pzhj 2321 1 The the DT cord-005646-xhx9pzhj 2321 2 average average JJ cord-005646-xhx9pzhj 2321 3 duration duration NN cord-005646-xhx9pzhj 2321 4 of of IN cord-005646-xhx9pzhj 2321 5 symptoms symptom NNS cord-005646-xhx9pzhj 2321 6 prior prior RB cord-005646-xhx9pzhj 2321 7 to to IN cord-005646-xhx9pzhj 2321 8 admission admission NN cord-005646-xhx9pzhj 2321 9 was be VBD cord-005646-xhx9pzhj 2321 10 20.4 20.4 CD cord-005646-xhx9pzhj 2321 11 hours hour NNS cord-005646-xhx9pzhj 2321 12 ( ( -LRB- cord-005646-xhx9pzhj 2321 13 + + CC cord-005646-xhx9pzhj 2321 14 /-14.09 /-14.09 . cord-005646-xhx9pzhj 2321 15 ) ) -RRB- cord-005646-xhx9pzhj 2321 16 . . . cord-005646-xhx9pzhj 2322 1 On on IN cord-005646-xhx9pzhj 2322 2 admission admission NN cord-005646-xhx9pzhj 2322 3 17.4 17.4 CD cord-005646-xhx9pzhj 2322 4 % % NN cord-005646-xhx9pzhj 2322 5 were be VBD cord-005646-xhx9pzhj 2322 6 hypotensive hypotensive JJ cord-005646-xhx9pzhj 2322 7 , , , cord-005646-xhx9pzhj 2322 8 45.6 45.6 CD cord-005646-xhx9pzhj 2322 9 % % NN cord-005646-xhx9pzhj 2322 10 had have VBD cord-005646-xhx9pzhj 2322 11 clinical clinical JJ cord-005646-xhx9pzhj 2322 12 signs sign NNS cord-005646-xhx9pzhj 2322 13 of of IN cord-005646-xhx9pzhj 2322 14 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 2322 15 instability instability NN cord-005646-xhx9pzhj 2322 16 and and CC cord-005646-xhx9pzhj 2322 17 54.8 54.8 CD cord-005646-xhx9pzhj 2322 18 % % NN cord-005646-xhx9pzhj 2322 19 of of IN cord-005646-xhx9pzhj 2322 20 cases case NNS cord-005646-xhx9pzhj 2322 21 that that WDT cord-005646-xhx9pzhj 2322 22 had have VBD cord-005646-xhx9pzhj 2322 23 a a DT cord-005646-xhx9pzhj 2322 24 blood blood NN cord-005646-xhx9pzhj 2322 25 gas gas NN cord-005646-xhx9pzhj 2322 26 analysis analysis NN cord-005646-xhx9pzhj 2322 27 on on IN cord-005646-xhx9pzhj 2322 28 admission admission NN cord-005646-xhx9pzhj 2322 29 had have VBD cord-005646-xhx9pzhj 2322 30 a a DT cord-005646-xhx9pzhj 2322 31 metabolic metabolic JJ cord-005646-xhx9pzhj 2322 32 acidosis acidosis NN cord-005646-xhx9pzhj 2323 1 ( ( -LRB- cord-005646-xhx9pzhj 2323 2 Bases basis NNS cord-005646-xhx9pzhj 2323 3 excess excess JJ cord-005646-xhx9pzhj 2323 4 < < XX cord-005646-xhx9pzhj 2323 5 -5.Q -5.Q NNS cord-005646-xhx9pzhj 2323 6 ) ) -RRB- cord-005646-xhx9pzhj 2324 1 : : : cord-005646-xhx9pzhj 2324 2 The the DT cord-005646-xhx9pzhj 2324 3 mortality mortality NN cord-005646-xhx9pzhj 2324 4 rate rate NN cord-005646-xhx9pzhj 2324 5 was be VBD cord-005646-xhx9pzhj 2324 6 10.9 10.9 CD cord-005646-xhx9pzhj 2324 7 % % NN cord-005646-xhx9pzhj 2324 8 . . . cord-005646-xhx9pzhj 2325 1 80 80 CD cord-005646-xhx9pzhj 2325 2 % % NN cord-005646-xhx9pzhj 2325 3 of of IN cord-005646-xhx9pzhj 2325 4 patients patient NNS cord-005646-xhx9pzhj 2325 5 that that WDT cord-005646-xhx9pzhj 2325 6 died die VBD cord-005646-xhx9pzhj 2325 7 were be VBD cord-005646-xhx9pzhj 2325 8 hypotensive hypotensive JJ cord-005646-xhx9pzhj 2325 9 on on IN cord-005646-xhx9pzhj 2325 10 admission admission NN cord-005646-xhx9pzhj 2325 11 and and CC cord-005646-xhx9pzhj 2325 12 all all DT cord-005646-xhx9pzhj 2325 13 had have VBD cord-005646-xhx9pzhj 2325 14 a a DT cord-005646-xhx9pzhj 2325 15 metabolic metabolic JJ cord-005646-xhx9pzhj 2325 16 acidosis acidosis NN cord-005646-xhx9pzhj 2325 17 . . . cord-005646-xhx9pzhj 2326 1 Of of IN cord-005646-xhx9pzhj 2326 2 the the DT cord-005646-xhx9pzhj 2326 3 41 41 CD cord-005646-xhx9pzhj 2326 4 survivors survivor NNS cord-005646-xhx9pzhj 2326 5 9.7 9.7 CD cord-005646-xhx9pzhj 2326 6 % % NN cord-005646-xhx9pzhj 2326 7 were be VBD cord-005646-xhx9pzhj 2326 8 hypotensive hypotensive JJ cord-005646-xhx9pzhj 2326 9 on on IN cord-005646-xhx9pzhj 2326 10 admission admission NN cord-005646-xhx9pzhj 2326 11 , , , cord-005646-xhx9pzhj 2326 12 39 39 CD cord-005646-xhx9pzhj 2326 13 % % NN cord-005646-xhx9pzhj 2326 14 had have VBD cord-005646-xhx9pzhj 2326 15 clinical clinical JJ cord-005646-xhx9pzhj 2326 16 signs sign NNS cord-005646-xhx9pzhj 2326 17 of of IN cord-005646-xhx9pzhj 2326 18 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 2326 19 instability instability NN cord-005646-xhx9pzhj 2326 20 , , , cord-005646-xhx9pzhj 2326 21 25 25 CD cord-005646-xhx9pzhj 2326 22 % % NN cord-005646-xhx9pzhj 2326 23 required require VBD cord-005646-xhx9pzhj 2326 24 invasive invasive JJ cord-005646-xhx9pzhj 2326 25 pressure pressure NN cord-005646-xhx9pzhj 2326 26 monitoring monitoring NN cord-005646-xhx9pzhj 2326 27 and and CC cord-005646-xhx9pzhj 2326 28 7.3 7.3 CD cord-005646-xhx9pzhj 2326 29 % % NN cord-005646-xhx9pzhj 2326 30 were be VBD cord-005646-xhx9pzhj 2326 31 ventilated ventilate VBN cord-005646-xhx9pzhj 2326 32 and and CC cord-005646-xhx9pzhj 2326 33 received receive VBD cord-005646-xhx9pzhj 2326 34 inotropic inotropic NNP cord-005646-xhx9pzhj 2326 35 support support NN cord-005646-xhx9pzhj 2326 36 . . . cord-005646-xhx9pzhj 2327 1 This this DT cord-005646-xhx9pzhj 2327 2 study study NN cord-005646-xhx9pzhj 2327 3 demonstrates demonstrate VBZ cord-005646-xhx9pzhj 2327 4 that that IN cord-005646-xhx9pzhj 2327 5 at at IN cord-005646-xhx9pzhj 2327 6 the the DT cord-005646-xhx9pzhj 2327 7 time time NN cord-005646-xhx9pzhj 2327 8 of of IN cord-005646-xhx9pzhj 2327 9 presentation presentation NN cord-005646-xhx9pzhj 2327 10 with with IN cord-005646-xhx9pzhj 2327 11 meningococcal meningococcal JJ cord-005646-xhx9pzhj 2327 12 infection infection NN cord-005646-xhx9pzhj 2327 13 children child NNS cord-005646-xhx9pzhj 2327 14 had have VBD cord-005646-xhx9pzhj 2327 15 a a DT cord-005646-xhx9pzhj 2327 16 high high JJ cord-005646-xhx9pzhj 2327 17 incidence incidence NN cord-005646-xhx9pzhj 2327 18 of of IN cord-005646-xhx9pzhj 2327 19 established establish VBN cord-005646-xhx9pzhj 2327 20 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 2327 21 instability instability NN cord-005646-xhx9pzhj 2327 22 . . . cord-005646-xhx9pzhj 2328 1 Successful successful JJ cord-005646-xhx9pzhj 2328 2 management management NN cord-005646-xhx9pzhj 2328 3 of of IN cord-005646-xhx9pzhj 2328 4 this this DT cord-005646-xhx9pzhj 2328 5 infection infection NN cord-005646-xhx9pzhj 2328 6 is be VBZ cord-005646-xhx9pzhj 2328 7 dependent dependent JJ cord-005646-xhx9pzhj 2328 8 on on IN cord-005646-xhx9pzhj 2328 9 early early JJ cord-005646-xhx9pzhj 2328 10 presentation presentation NN cord-005646-xhx9pzhj 2328 11 and and CC cord-005646-xhx9pzhj 2328 12 initiation initiation NN cord-005646-xhx9pzhj 2328 13 of of IN cord-005646-xhx9pzhj 2328 14 therapy therapy NN cord-005646-xhx9pzhj 2328 15 and and CC cord-005646-xhx9pzhj 2328 16 on on IN cord-005646-xhx9pzhj 2328 17 aggressive aggressive JJ cord-005646-xhx9pzhj 2328 18 support support NN cord-005646-xhx9pzhj 2328 19 of of IN cord-005646-xhx9pzhj 2328 20 the the DT cord-005646-xhx9pzhj 2328 21 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 2328 22 and and CC cord-005646-xhx9pzhj 2328 23 vital vital JJ cord-005646-xhx9pzhj 2328 24 organ organ NN cord-005646-xhx9pzhj 2328 25 systems system NNS cord-005646-xhx9pzhj 2328 26 . . . cord-005646-xhx9pzhj 2329 1 Dept Dept NNP cord-005646-xhx9pzhj 2329 2 . . NNP cord-005646-xhx9pzhj 2329 3 of of IN cord-005646-xhx9pzhj 2329 4 Intensive Intensive NNP cord-005646-xhx9pzhj 2329 5 Care Care NNP cord-005646-xhx9pzhj 2329 6 Medicine Medicine NNP cord-005646-xhx9pzhj 2329 7 and and CC cord-005646-xhx9pzhj 2329 8 Dept Dept NNP cord-005646-xhx9pzhj 2329 9 of of IN cord-005646-xhx9pzhj 2329 10 Infectious Infectious NNP cord-005646-xhx9pzhj 2329 11 Diseases Diseases NNPS cord-005646-xhx9pzhj 2329 12 , , , cord-005646-xhx9pzhj 2329 13 Our -PRON- PRP$ cord-005646-xhx9pzhj 2329 14 Lady Lady NNP cord-005646-xhx9pzhj 2329 15 's 's POS cord-005646-xhx9pzhj 2329 16 Hospital Hospital NNP cord-005646-xhx9pzhj 2329 17 for for IN cord-005646-xhx9pzhj 2329 18 Sick Sick NNP cord-005646-xhx9pzhj 2329 19 Children Children NNPS cord-005646-xhx9pzhj 2329 20 , , , cord-005646-xhx9pzhj 2329 21 Crumlin Crumlin NNP cord-005646-xhx9pzhj 2329 22 , , , cord-005646-xhx9pzhj 2329 23 Dublinl2 Dublinl2 NNP cord-005646-xhx9pzhj 2329 24 , , , cord-005646-xhx9pzhj 2329 25 Ireland Ireland NNP cord-005646-xhx9pzhj 2329 26 . . . cord-005646-xhx9pzhj 2330 1 Jude Jude NNP cord-005646-xhx9pzhj 2330 2 . . . cord-005646-xhx9pzhj 2331 1 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2331 2 Intensive Intensive NNP cord-005646-xhx9pzhj 2331 3 Care Care NNP cord-005646-xhx9pzhj 2331 4 Unit Unit NNP cord-005646-xhx9pzhj 2331 5 , , , cord-005646-xhx9pzhj 2331 6 CH&U CH&U NNP cord-005646-xhx9pzhj 2331 7 , , , cord-005646-xhx9pzhj 2331 8 59037 59037 CD cord-005646-xhx9pzhj 2331 9 LILLE LILLE NNP cord-005646-xhx9pzhj 2331 10 - - HYPH cord-005646-xhx9pzhj 2331 11 France France NNP cord-005646-xhx9pzhj 2331 12 . . . cord-005646-xhx9pzhj 2332 1 More More JJR cord-005646-xhx9pzhj 2332 2 than than IN cord-005646-xhx9pzhj 2332 3 10 10 CD cord-005646-xhx9pzhj 2332 4 % % NN cord-005646-xhx9pzhj 2332 5 of of IN cord-005646-xhx9pzhj 2332 6 children child NNS cord-005646-xhx9pzhj 2332 7 surviving survive VBG cord-005646-xhx9pzhj 2332 8 SIP sip NN cord-005646-xhx9pzhj 2332 9 ( ( -LRB- cord-005646-xhx9pzhj 2332 10 defined define VBN cord-005646-xhx9pzhj 2332 11 as as IN cord-005646-xhx9pzhj 2332 12 purpura purpura NN cord-005646-xhx9pzhj 2332 13 with with IN cord-005646-xhx9pzhj 2332 14 shock shock NN cord-005646-xhx9pzhj 2332 15 ) ) -RRB- cord-005646-xhx9pzhj 2332 16 have have VBP cord-005646-xhx9pzhj 2332 17 SNLI SNLI NNP cord-005646-xhx9pzhj 2332 18 . . . cord-005646-xhx9pzhj 2333 1 Objective objective JJ cord-005646-xhx9pzhj 2333 2 . . . cord-005646-xhx9pzhj 2334 1 To to TO cord-005646-xhx9pzhj 2334 2 search search VB cord-005646-xhx9pzhj 2334 3 for for IN cord-005646-xhx9pzhj 2334 4 a a DT cord-005646-xhx9pzhj 2334 5 specific specific JJ cord-005646-xhx9pzhj 2334 6 hemostatic hemostatic JJ cord-005646-xhx9pzhj 2334 7 profile profile NN cord-005646-xhx9pzhj 2334 8 in in IN cord-005646-xhx9pzhj 2334 9 children child NNS cord-005646-xhx9pzhj 2334 10 with with IN cord-005646-xhx9pzhj 2334 11 SNLI SNLI NNP cord-005646-xhx9pzhj 2334 12 . . . cord-005646-xhx9pzhj 2335 1 Patients patient NNS cord-005646-xhx9pzhj 2335 2 and and CC cord-005646-xhx9pzhj 2335 3 methods method NNS cord-005646-xhx9pzhj 2335 4 . . . cord-005646-xhx9pzhj 2336 1 Between between IN cord-005646-xhx9pzhj 2336 2 May May NNP cord-005646-xhx9pzhj 2336 3 1989 1989 CD cord-005646-xhx9pzhj 2336 4 and and CC cord-005646-xhx9pzhj 2336 5 March March NNP cord-005646-xhx9pzhj 2336 6 1995 1995 CD cord-005646-xhx9pzhj 2336 7 , , , cord-005646-xhx9pzhj 2336 8 34 34 CD cord-005646-xhx9pzhj 2336 9 children child NNS cord-005646-xhx9pzhj 2336 10 with with IN cord-005646-xhx9pzhj 2336 11 SIP SIP NNP cord-005646-xhx9pzhj 2336 12 were be VBD cord-005646-xhx9pzhj 2336 13 admitted admit VBN cord-005646-xhx9pzhj 2336 14 to to IN cord-005646-xhx9pzhj 2336 15 our -PRON- PRP$ cord-005646-xhx9pzhj 2336 16 PICU PICU NNP cord-005646-xhx9pzhj 2336 17 : : : cord-005646-xhx9pzhj 2336 18 6 6 CD cord-005646-xhx9pzhj 2336 19 ( ( -LRB- cord-005646-xhx9pzhj 2336 20 17.6 17.6 CD cord-005646-xhx9pzhj 2336 21 % % NN cord-005646-xhx9pzhj 2336 22 ) ) -RRB- cord-005646-xhx9pzhj 2336 23 died die VBD cord-005646-xhx9pzhj 2336 24 and and CC cord-005646-xhx9pzhj 2336 25 28 28 CD cord-005646-xhx9pzhj 2336 26 ( ( -LRB- cord-005646-xhx9pzhj 2336 27 82.4 82.4 CD cord-005646-xhx9pzhj 2336 28 % % NN cord-005646-xhx9pzhj 2336 29 ) ) -RRB- cord-005646-xhx9pzhj 2336 30 ranged range VBD cord-005646-xhx9pzhj 2336 31 in in IN cord-005646-xhx9pzhj 2336 32 age age NN cord-005646-xhx9pzhj 2336 33 from from IN cord-005646-xhx9pzhj 2336 34 1 1 CD cord-005646-xhx9pzhj 2336 35 to to IN cord-005646-xhx9pzhj 2336 36 185 185 CD cord-005646-xhx9pzhj 2336 37 months month NNS cord-005646-xhx9pzhj 2336 38 ( ( -LRB- cord-005646-xhx9pzhj 2336 39 mean mean VB cord-005646-xhx9pzhj 2336 40 : : : cord-005646-xhx9pzhj 2336 41 29 29 CD cord-005646-xhx9pzhj 2336 42 ) ) -RRB- cord-005646-xhx9pzhj 2336 43 survived survive VBD cord-005646-xhx9pzhj 2336 44 , , , cord-005646-xhx9pzhj 2336 45 5 5 CD cord-005646-xhx9pzhj 2336 46 of of IN cord-005646-xhx9pzhj 2336 47 them -PRON- PRP cord-005646-xhx9pzhj 2336 48 ( ( -LRB- cord-005646-xhx9pzhj 2336 49 17.8 17.8 CD cord-005646-xhx9pzhj 2336 50 % % NN cord-005646-xhx9pzhj 2336 51 ) ) -RRB- cord-005646-xhx9pzhj 2336 52 with with IN cord-005646-xhx9pzhj 2336 53 SNLI SNLI NNP cord-005646-xhx9pzhj 2336 54 ( ( -LRB- cord-005646-xhx9pzhj 2336 55 defined define VBN cord-005646-xhx9pzhj 2336 56 as as IN cord-005646-xhx9pzhj 2336 57 the the DT cord-005646-xhx9pzhj 2336 58 need need NN cord-005646-xhx9pzhj 2336 59 of of IN cord-005646-xhx9pzhj 2336 60 a a DT cord-005646-xhx9pzhj 2336 61 surgical surgical JJ cord-005646-xhx9pzhj 2336 62 procedure procedure NN cord-005646-xhx9pzhj 2336 63 ) ) -RRB- cord-005646-xhx9pzhj 2336 64 . . . cord-005646-xhx9pzhj 2337 1 In in IN cord-005646-xhx9pzhj 2337 2 survivors survivor NNS cord-005646-xhx9pzhj 2337 3 , , , cord-005646-xhx9pzhj 2337 4 two two CD cord-005646-xhx9pzhj 2337 5 hemostasis hemostasis NN cord-005646-xhx9pzhj 2337 6 studies study NNS cord-005646-xhx9pzhj 2337 7 ( ( -LRB- cord-005646-xhx9pzhj 2337 8 between between IN cord-005646-xhx9pzhj 2337 9 H0 H0 NNP cord-005646-xhx9pzhj 2337 10 and and CC cord-005646-xhx9pzhj 2337 11 H12 H12 NNP cord-005646-xhx9pzhj 2337 12 , , , cord-005646-xhx9pzhj 2337 13 and and CC cord-005646-xhx9pzhj 2337 14 24 24 CD cord-005646-xhx9pzhj 2337 15 H h NN cord-005646-xhx9pzhj 2337 16 later later RB cord-005646-xhx9pzhj 2337 17 ) ) -RRB- cord-005646-xhx9pzhj 2337 18 included include VBD cord-005646-xhx9pzhj 2337 19 the the DT cord-005646-xhx9pzhj 2337 20 determination determination NN cord-005646-xhx9pzhj 2337 21 of of IN cord-005646-xhx9pzhj 2337 22 coagulation coagulation NN cord-005646-xhx9pzhj 2337 23 factors factor NNS cord-005646-xhx9pzhj 2337 24 ( ( -LRB- cord-005646-xhx9pzhj 2337 25 routine routine JJ cord-005646-xhx9pzhj 2337 26 tests test NNS cord-005646-xhx9pzhj 2337 27 ) ) -RRB- cord-005646-xhx9pzhj 2337 28 , , , cord-005646-xhx9pzhj 2337 29 protein protein NN cord-005646-xhx9pzhj 2337 30 C C NNP cord-005646-xhx9pzhj 2337 31 ( ( -LRB- cord-005646-xhx9pzhj 2337 32 PC pc NN cord-005646-xhx9pzhj 2337 33 : : : cord-005646-xhx9pzhj 2337 34 amidolytic amidolytic JJ cord-005646-xhx9pzhj 2337 35 activity activity NN cord-005646-xhx9pzhj 2337 36 , , , cord-005646-xhx9pzhj 2337 37 Biogenic Biogenic NNP cord-005646-xhx9pzhj 2337 38 ) ) -RRB- cord-005646-xhx9pzhj 2337 39 , , , cord-005646-xhx9pzhj 2337 40 total total JJ cord-005646-xhx9pzhj 2337 41 protein protein NN cord-005646-xhx9pzhj 2337 42 S S NNP cord-005646-xhx9pzhj 2337 43 ( ( -LRB- cord-005646-xhx9pzhj 2337 44 PS PS NNP cord-005646-xhx9pzhj 2337 45 : : : cord-005646-xhx9pzhj 2337 46 ELISA ELISA NNP cord-005646-xhx9pzhj 2337 47 , , , cord-005646-xhx9pzhj 2337 48 Stago Stago NNP cord-005646-xhx9pzhj 2337 49 ) ) -RRB- cord-005646-xhx9pzhj 2337 50 , , , cord-005646-xhx9pzhj 2337 51 C4b c4b NN cord-005646-xhx9pzhj 2337 52 binding bind VBG cord-005646-xhx9pzhj 2337 53 protein protein NN cord-005646-xhx9pzhj 2337 54 ( ( -LRB- cord-005646-xhx9pzhj 2337 55 C4bBP C4bBP NNP cord-005646-xhx9pzhj 2337 56 : : : cord-005646-xhx9pzhj 2338 1 Laurell Laurell NNP cord-005646-xhx9pzhj 2338 2 's 's POS cord-005646-xhx9pzhj 2338 3 technique technique NN cord-005646-xhx9pzhj 2338 4 , , , cord-005646-xhx9pzhj 2338 5 Stago Stago NNP cord-005646-xhx9pzhj 2338 6 ) ) -RRB- cord-005646-xhx9pzhj 2338 7 , , , cord-005646-xhx9pzhj 2338 8 antithrombin3 antithrombin3 NN cord-005646-xhx9pzhj 2338 9 ( ( -LRB- cord-005646-xhx9pzhj 2338 10 AT3 at3 NN cord-005646-xhx9pzhj 2338 11 : : : cord-005646-xhx9pzhj 2338 12 chomogenic chomogenic NNP cord-005646-xhx9pzhj 2338 13 test test NN cord-005646-xhx9pzhj 2338 14 , , , cord-005646-xhx9pzhj 2338 15 Stago Stago NNP cord-005646-xhx9pzhj 2338 16 ) ) -RRB- cord-005646-xhx9pzhj 2338 17 , , , cord-005646-xhx9pzhj 2338 18 and and CC cord-005646-xhx9pzhj 2338 19 plasminogen plasminogen NN cord-005646-xhx9pzhj 2338 20 activator activator NN cord-005646-xhx9pzhj 2338 21 inhibitorl inhibitorl NNP cord-005646-xhx9pzhj 2338 22 ( ( -LRB- cord-005646-xhx9pzhj 2338 23 PAIl PAIl NNP cord-005646-xhx9pzhj 2338 24 : : : cord-005646-xhx9pzhj 2338 25 chromogenic chromogenic NNP cord-005646-xhx9pzhj 2338 26 test test NN cord-005646-xhx9pzhj 2338 27 , , , cord-005646-xhx9pzhj 2338 28 Biopool Biopool NNP cord-005646-xhx9pzhj 2338 29 ) ) -RRB- cord-005646-xhx9pzhj 2338 30 . . . cord-005646-xhx9pzhj 2339 1 Three three CD cord-005646-xhx9pzhj 2339 2 severity severity NN cord-005646-xhx9pzhj 2339 3 scores score NNS cord-005646-xhx9pzhj 2339 4 were be VBD cord-005646-xhx9pzhj 2339 5 determined determine VBN cord-005646-xhx9pzhj 2339 6 at at IN cord-005646-xhx9pzhj 2339 7 admission admission NN cord-005646-xhx9pzhj 2339 8 : : : cord-005646-xhx9pzhj 2340 1 French French NNP cord-005646-xhx9pzhj 2340 2 Group Group NNP cord-005646-xhx9pzhj 2340 3 of of IN cord-005646-xhx9pzhj 2340 4 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2340 5 Intensive Intensive NNP cord-005646-xhx9pzhj 2340 6 Care Care NNP cord-005646-xhx9pzhj 2340 7 , , , cord-005646-xhx9pzhj 2340 8 Gedde Gedde NNP cord-005646-xhx9pzhj 2340 9 - - HYPH cord-005646-xhx9pzhj 2340 10 Dahl Dahl NNP cord-005646-xhx9pzhj 2340 11 , , , cord-005646-xhx9pzhj 2340 12 and and CC cord-005646-xhx9pzhj 2340 13 CRP CRP NNP cord-005646-xhx9pzhj 2340 14 . . . cord-005646-xhx9pzhj 2341 1 Statistical statistical JJ cord-005646-xhx9pzhj 2341 2 analysis analysis NN cord-005646-xhx9pzhj 2341 3 used use VBD cord-005646-xhx9pzhj 2341 4 the the DT cord-005646-xhx9pzhj 2341 5 Wilcoxon Wilcoxon NNP cord-005646-xhx9pzhj 2341 6 's 's POS cord-005646-xhx9pzhj 2341 7 test test NN cord-005646-xhx9pzhj 2341 8 . . . cord-005646-xhx9pzhj 2342 1 Results result NNS cord-005646-xhx9pzhj 2342 2 . . . cord-005646-xhx9pzhj 2343 1 At at IN cord-005646-xhx9pzhj 2343 2 admission admission NN cord-005646-xhx9pzhj 2343 3 ( ( -LRB- cord-005646-xhx9pzhj 2343 4 lst lst NNP cord-005646-xhx9pzhj 2343 5 sample sample NN cord-005646-xhx9pzhj 2343 6 ) ) -RRB- cord-005646-xhx9pzhj 2343 7 severity severity NN cord-005646-xhx9pzhj 2343 8 scores score NNS cord-005646-xhx9pzhj 2343 9 and and CC cord-005646-xhx9pzhj 2343 10 AT3 at3 NN cord-005646-xhx9pzhj 2343 11 , , , cord-005646-xhx9pzhj 2343 12 PC PC NNP cord-005646-xhx9pzhj 2343 13 , , , cord-005646-xhx9pzhj 2343 14 PS PS NNP cord-005646-xhx9pzhj 2343 15 , , , cord-005646-xhx9pzhj 2343 16 C4bBP C4bBP NNP cord-005646-xhx9pzhj 2343 17 levels level NNS cord-005646-xhx9pzhj 2343 18 were be VBD cord-005646-xhx9pzhj 2343 19 not not RB cord-005646-xhx9pzhj 2343 20 different different JJ cord-005646-xhx9pzhj 2343 21 between between IN cord-005646-xhx9pzhj 2343 22 the the DT cord-005646-xhx9pzhj 2343 23 group group NN cord-005646-xhx9pzhj 2343 24 with with IN cord-005646-xhx9pzhj 2343 25 SNLI SNLI NNP cord-005646-xhx9pzhj 2343 26 and and CC cord-005646-xhx9pzhj 2343 27 the the DT cord-005646-xhx9pzhj 2343 28 group group NN cord-005646-xhx9pzhj 2343 29 without without IN cord-005646-xhx9pzhj 2343 30 SNLI SNLI NNP cord-005646-xhx9pzhj 2343 31 ; ; : cord-005646-xhx9pzhj 2343 32 Quick quick JJ cord-005646-xhx9pzhj 2343 33 time time NN cord-005646-xhx9pzhj 2343 34 ( ( -LRB- cord-005646-xhx9pzhj 2343 35 22 22 CD cord-005646-xhx9pzhj 2343 36 4 4 CD cord-005646-xhx9pzhj 2343 37 - - SYM cord-005646-xhx9pzhj 2343 38 5 5 CD cord-005646-xhx9pzhj 2343 39 % % NN cord-005646-xhx9pzhj 2343 40 vs vs IN cord-005646-xhx9pzhj 2343 41 35 35 CD cord-005646-xhx9pzhj 2343 42 ± ± CD cord-005646-xhx9pzhj 2343 43 14 14 CD cord-005646-xhx9pzhj 2343 44 % % NN cord-005646-xhx9pzhj 2343 45 ; ; : cord-005646-xhx9pzhj 2343 46 p p NN cord-005646-xhx9pzhj 2343 47 = = SYM cord-005646-xhx9pzhj 2343 48 .025 .025 CD cord-005646-xhx9pzhj 2343 49 ) ) -RRB- cord-005646-xhx9pzhj 2343 50 , , , cord-005646-xhx9pzhj 2343 51 VtI+X VtI+X NNP cord-005646-xhx9pzhj 2343 52 ( ( -LRB- cord-005646-xhx9pzhj 2344 1 20 20 CD cord-005646-xhx9pzhj 2344 2 4 4 CD cord-005646-xhx9pzhj 2344 3 . . . cord-005646-xhx9pzhj 2345 1 3 3 CD cord-005646-xhx9pzhj 2345 2 % % NN cord-005646-xhx9pzhj 2345 3 vs vs IN cord-005646-xhx9pzhj 2345 4 30 30 CD cord-005646-xhx9pzhj 2345 5 4 4 CD cord-005646-xhx9pzhj 2345 6 - - SYM cord-005646-xhx9pzhj 2345 7 10 10 CD cord-005646-xhx9pzhj 2345 8 % % NN cord-005646-xhx9pzhj 2345 9 ; ; : cord-005646-xhx9pzhj 2345 10 p p NN cord-005646-xhx9pzhj 2345 11 = = SYM cord-005646-xhx9pzhj 2345 12 .04I .04I NFP cord-005646-xhx9pzhj 2345 13 ) ) -RRB- cord-005646-xhx9pzhj 2346 1 and and CC cord-005646-xhx9pzhj 2346 2 PAll PAll NNP cord-005646-xhx9pzhj 2346 3 ( ( -LRB- cord-005646-xhx9pzhj 2346 4 105 105 CD cord-005646-xhx9pzhj 2346 5 4 4 CD cord-005646-xhx9pzhj 2346 6 - - SYM cord-005646-xhx9pzhj 2346 7 157 157 CD cord-005646-xhx9pzhj 2346 8 UI UI NNP cord-005646-xhx9pzhj 2346 9 / / SYM cord-005646-xhx9pzhj 2346 10 m m NN cord-005646-xhx9pzhj 2346 11 ! ! . cord-005646-xhx9pzhj 2346 12 vs vs IN cord-005646-xhx9pzhj 2346 13 580 580 CD cord-005646-xhx9pzhj 2346 14 4 4 CD cord-005646-xhx9pzhj 2346 15 . . . cord-005646-xhx9pzhj 2347 1 570 570 CD cord-005646-xhx9pzhj 2347 2 UI UI NNP cord-005646-xhx9pzhj 2347 3 / / SYM cord-005646-xhx9pzhj 2347 4 ml ml NN cord-005646-xhx9pzhj 2347 5 ; ; : cord-005646-xhx9pzhj 2347 6 p p NN cord-005646-xhx9pzhj 2347 7 = = SYM cord-005646-xhx9pzhj 2347 8 .028 .028 CD cord-005646-xhx9pzhj 2347 9 ) ) -RRB- cord-005646-xhx9pzhj 2347 10 were be VBD cord-005646-xhx9pzhj 2347 11 lower low JJR cord-005646-xhx9pzhj 2347 12 in in IN cord-005646-xhx9pzhj 2347 13 the the DT cord-005646-xhx9pzhj 2347 14 group group NN cord-005646-xhx9pzhj 2347 15 with with IN cord-005646-xhx9pzhj 2347 16 SNLI SNLI NNP cord-005646-xhx9pzhj 2347 17 . . . cord-005646-xhx9pzhj 2348 1 On on IN cord-005646-xhx9pzhj 2348 2 the the DT cord-005646-xhx9pzhj 2348 3 2nd 2nd JJ cord-005646-xhx9pzhj 2348 4 sample sample NN cord-005646-xhx9pzhj 2348 5 there there EX cord-005646-xhx9pzhj 2348 6 was be VBD cord-005646-xhx9pzhj 2348 7 no no DT cord-005646-xhx9pzhj 2348 8 difference difference NN cord-005646-xhx9pzhj 2348 9 between between IN cord-005646-xhx9pzhj 2348 10 the the DT cord-005646-xhx9pzhj 2348 11 two two CD cord-005646-xhx9pzhj 2348 12 groups group NNS cord-005646-xhx9pzhj 2348 13 . . . cord-005646-xhx9pzhj 2349 1 Kinetics kinetic NNS cord-005646-xhx9pzhj 2349 2 of of IN cord-005646-xhx9pzhj 2349 3 hemostatic hemostatic JJ cord-005646-xhx9pzhj 2349 4 abnormalities abnormality NNS cord-005646-xhx9pzhj 2349 5 was be VBD cord-005646-xhx9pzhj 2349 6 not not RB cord-005646-xhx9pzhj 2349 7 different different JJ cord-005646-xhx9pzhj 2349 8 between between IN cord-005646-xhx9pzhj 2349 9 the the DT cord-005646-xhx9pzhj 2349 10 two two CD cord-005646-xhx9pzhj 2349 11 groups group NNS cord-005646-xhx9pzhj 2349 12 . . . cord-005646-xhx9pzhj 2350 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2350 2 . . . cord-005646-xhx9pzhj 2351 1 In in IN cord-005646-xhx9pzhj 2351 2 the the DT cord-005646-xhx9pzhj 2351 3 literature literature NN cord-005646-xhx9pzhj 2351 4 , , , cord-005646-xhx9pzhj 2351 5 intravascular intravascular JJ cord-005646-xhx9pzhj 2351 6 coagulation coagulation NN cord-005646-xhx9pzhj 2351 7 ( ( -LRB- cord-005646-xhx9pzhj 2351 8 DIC DIC NNP cord-005646-xhx9pzhj 2351 9 ) ) -RRB- cord-005646-xhx9pzhj 2351 10 , , , cord-005646-xhx9pzhj 2351 11 low low JJ cord-005646-xhx9pzhj 2351 12 fibronectin fibronectin NN cord-005646-xhx9pzhj 2351 13 and and CC cord-005646-xhx9pzhj 2351 14 AT3 at3 NN cord-005646-xhx9pzhj 2351 15 were be VBD cord-005646-xhx9pzhj 2351 16 identified identify VBN cord-005646-xhx9pzhj 2351 17 as as IN cord-005646-xhx9pzhj 2351 18 predictors predictor NNS cord-005646-xhx9pzhj 2351 19 of of IN cord-005646-xhx9pzhj 2351 20 SNLI SNLI NNP cord-005646-xhx9pzhj 2351 21 , , , cord-005646-xhx9pzhj 2351 22 and and CC cord-005646-xhx9pzhj 2351 23 a a DT cord-005646-xhx9pzhj 2351 24 negative negative JJ cord-005646-xhx9pzhj 2351 25 correlation correlation NN cord-005646-xhx9pzhj 2351 26 was be VBD cord-005646-xhx9pzhj 2351 27 found find VBN cord-005646-xhx9pzhj 2351 28 between between IN cord-005646-xhx9pzhj 2351 29 the the DT cord-005646-xhx9pzhj 2351 30 mean mean JJ cord-005646-xhx9pzhj 2351 31 size size NN cord-005646-xhx9pzhj 2351 32 of of IN cord-005646-xhx9pzhj 2351 33 the the DT cord-005646-xhx9pzhj 2351 34 skin skin NN cord-005646-xhx9pzhj 2351 35 lesions lesion NNS cord-005646-xhx9pzhj 2351 36 and and CC cord-005646-xhx9pzhj 2351 37 PC pc NN cord-005646-xhx9pzhj 2351 38 activity activity NN cord-005646-xhx9pzhj 2351 39 , , , cord-005646-xhx9pzhj 2351 40 AT3 at3 NN cord-005646-xhx9pzhj 2351 41 , , , cord-005646-xhx9pzhj 2351 42 and and CC cord-005646-xhx9pzhj 2351 43 total total JJ cord-005646-xhx9pzhj 2351 44 PS PS NNP cord-005646-xhx9pzhj 2351 45 . . . cord-005646-xhx9pzhj 2352 1 In in IN cord-005646-xhx9pzhj 2352 2 this this DT cord-005646-xhx9pzhj 2352 3 series series NN cord-005646-xhx9pzhj 2352 4 , , , cord-005646-xhx9pzhj 2352 5 apart apart RB cord-005646-xhx9pzhj 2352 6 from from IN cord-005646-xhx9pzhj 2352 7 DIC DIC NNP cord-005646-xhx9pzhj 2352 8 , , , cord-005646-xhx9pzhj 2352 9 there there EX cord-005646-xhx9pzhj 2352 10 were be VBD cord-005646-xhx9pzhj 2352 11 no no DT cord-005646-xhx9pzhj 2352 12 specific specific JJ cord-005646-xhx9pzhj 2352 13 hemostatic hemostatic JJ cord-005646-xhx9pzhj 2352 14 abnormalities abnormality NNS cord-005646-xhx9pzhj 2352 15 that that WDT cord-005646-xhx9pzhj 2352 16 support support VBP cord-005646-xhx9pzhj 2352 17 the the DT cord-005646-xhx9pzhj 2352 18 use use NN cord-005646-xhx9pzhj 2352 19 of of IN cord-005646-xhx9pzhj 2352 20 treatments treatment NNS cord-005646-xhx9pzhj 2352 21 such such JJ cord-005646-xhx9pzhj 2352 22 as as IN cord-005646-xhx9pzhj 2352 23 PC pc NN cord-005646-xhx9pzhj 2352 24 , , , cord-005646-xhx9pzhj 2352 25 AT3 at3 NN cord-005646-xhx9pzhj 2352 26 , , , cord-005646-xhx9pzhj 2352 27 and and CC cord-005646-xhx9pzhj 2352 28 PAIl PAIl NNP cord-005646-xhx9pzhj 2352 29 antibodies antibody NNS cord-005646-xhx9pzhj 2352 30 administration administration NN cord-005646-xhx9pzhj 2352 31 to to TO cord-005646-xhx9pzhj 2352 32 prevent prevent VB cord-005646-xhx9pzhj 2352 33 SNLI SNLI NNP cord-005646-xhx9pzhj 2352 34 . . . cord-005646-xhx9pzhj 2353 1 Further further JJ cord-005646-xhx9pzhj 2353 2 studies study NNS cord-005646-xhx9pzhj 2353 3 including include VBG cord-005646-xhx9pzhj 2353 4 more more JJR cord-005646-xhx9pzhj 2353 5 children child NNS cord-005646-xhx9pzhj 2353 6 are be VBP cord-005646-xhx9pzhj 2353 7 needed need VBN cord-005646-xhx9pzhj 2353 8 . . . cord-005646-xhx9pzhj 2354 1 The the DT cord-005646-xhx9pzhj 2354 2 aim aim NN cord-005646-xhx9pzhj 2354 3 of of IN cord-005646-xhx9pzhj 2354 4 study study NN cord-005646-xhx9pzhj 2354 5 was be VBD cord-005646-xhx9pzhj 2354 6 to to TO cord-005646-xhx9pzhj 2354 7 investigate investigate VB cord-005646-xhx9pzhj 2354 8 the the DT cord-005646-xhx9pzhj 2354 9 efficacy efficacy NN cord-005646-xhx9pzhj 2354 10 of of IN cord-005646-xhx9pzhj 2354 11 intravenous intravenous JJ cord-005646-xhx9pzhj 2354 12 immunglobulin immunglobulin NN cord-005646-xhx9pzhj 2354 13 with with IN cord-005646-xhx9pzhj 2354 14 enriched enrich VBN cord-005646-xhx9pzhj 2354 15 IgM IgM NNP cord-005646-xhx9pzhj 2354 16 content content NN cord-005646-xhx9pzhj 2355 1 Pentaglob Pentaglob NNP cord-005646-xhx9pzhj 2355 2 / / SYM cord-005646-xhx9pzhj 2355 3 n n NN cord-005646-xhx9pzhj 2355 4 /Biotest/. /Biotest/. NNP cord-005646-xhx9pzhj 2356 1 In in IN cord-005646-xhx9pzhj 2356 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2356 3 pediatric pediatric JJ cord-005646-xhx9pzhj 2356 4 intensive intensive JJ cord-005646-xhx9pzhj 2356 5 care care NN cord-005646-xhx9pzhj 2356 6 unit unit NN cord-005646-xhx9pzhj 2356 7 ten ten CD cord-005646-xhx9pzhj 2356 8 septic septic JJ cord-005646-xhx9pzhj 2356 9 children child NNS cord-005646-xhx9pzhj 2356 10 /group /group . cord-005646-xhx9pzhj 2357 1 I/-their i/-their JJ cord-005646-xhx9pzhj 2357 2 average average JJ cord-005646-xhx9pzhj 2357 3 age age NN cord-005646-xhx9pzhj 2357 4 2,6 2,6 CD cord-005646-xhx9pzhj 2357 5 years year NNS cord-005646-xhx9pzhj 2358 1 /SD /SD NFP cord-005646-xhx9pzhj 2358 2 : : : cord-005646-xhx9pzhj 2358 3 O,6/ O,6/ NNS cord-005646-xhx9pzhj 2358 4 , , , cord-005646-xhx9pzhj 2358 5 7 7 CD cord-005646-xhx9pzhj 2358 6 of of IN cord-005646-xhx9pzhj 2358 7 them -PRON- PRP cord-005646-xhx9pzhj 2358 8 with with IN cord-005646-xhx9pzhj 2358 9 Gramm Gramm NNP cord-005646-xhx9pzhj 2359 1 negative negative JJ cord-005646-xhx9pzhj 2359 2 and and CC cord-005646-xhx9pzhj 2359 3 one one CD cord-005646-xhx9pzhj 2359 4 with with IN cord-005646-xhx9pzhj 2359 5 Gramm Gramm NNP cord-005646-xhx9pzhj 2359 6 positive positive JJ cord-005646-xhx9pzhj 2359 7 blood blood NN cord-005646-xhx9pzhj 2359 8 cultures culture NNS cord-005646-xhx9pzhj 2359 9 , , , cord-005646-xhx9pzhj 2359 10 and and CC cord-005646-xhx9pzhj 2359 11 two two CD cord-005646-xhx9pzhj 2359 12 with with IN cord-005646-xhx9pzhj 2359 13 unindentified unindentified JJ cord-005646-xhx9pzhj 2359 14 bacteria bacteria NNS cord-005646-xhx9pzhj 2359 15 - - , cord-005646-xhx9pzhj 2359 16 were be VBD cord-005646-xhx9pzhj 2359 17 treated treat VBN cord-005646-xhx9pzhj 2359 18 with with IN cord-005646-xhx9pzhj 2359 19 basis basis NN cord-005646-xhx9pzhj 2359 20 sepsis sepsis NN cord-005646-xhx9pzhj 2359 21 therapy therapy NN cord-005646-xhx9pzhj 2359 22 and and CC cord-005646-xhx9pzhj 2359 23 Pentaglobin Pentaglobin NNP cord-005646-xhx9pzhj 2359 24 . . . cord-005646-xhx9pzhj 2360 1 The the DT cord-005646-xhx9pzhj 2360 2 application application NN cord-005646-xhx9pzhj 2360 3 of of IN cord-005646-xhx9pzhj 2360 4 Pentaglobin Pentaglobin NNP cord-005646-xhx9pzhj 2360 5 was be VBD cord-005646-xhx9pzhj 2360 6 as as IN cord-005646-xhx9pzhj 2360 7 follows follow VBZ cord-005646-xhx9pzhj 2360 8 : : : cord-005646-xhx9pzhj 2360 9 1,5 1,5 CD cord-005646-xhx9pzhj 2360 10 ml ml NN cord-005646-xhx9pzhj 2360 11 / / SYM cord-005646-xhx9pzhj 2360 12 kg kg NN cord-005646-xhx9pzhj 2360 13 loading loading NN cord-005646-xhx9pzhj 2360 14 dose dose NN cord-005646-xhx9pzhj 2360 15 for for IN cord-005646-xhx9pzhj 2360 16 one one CD cord-005646-xhx9pzhj 2360 17 hour hour NN cord-005646-xhx9pzhj 2360 18 , , , cord-005646-xhx9pzhj 2360 19 followed follow VBN cord-005646-xhx9pzhj 2360 20 by by IN cord-005646-xhx9pzhj 2360 21 a a DT cord-005646-xhx9pzhj 2360 22 continuous continuous JJ cord-005646-xhx9pzhj 2360 23 intravenous intravenous JJ cord-005646-xhx9pzhj 2360 24 infusion infusion NN cord-005646-xhx9pzhj 2360 25 0,1 0,1 CD cord-005646-xhx9pzhj 2360 26 - - HYPH cord-005646-xhx9pzhj 2360 27 0,4 0,4 CD cord-005646-xhx9pzhj 2361 1 ml ml NNP cord-005646-xhx9pzhj 2361 2 / / SYM cord-005646-xhx9pzhj 2361 3 kg kg NN cord-005646-xhx9pzhj 2361 4 / / SYM cord-005646-xhx9pzhj 2361 5 hour hour NN cord-005646-xhx9pzhj 2361 6 depending depend VBG cord-005646-xhx9pzhj 2361 7 on on IN cord-005646-xhx9pzhj 2361 8 body body NN cord-005646-xhx9pzhj 2361 9 temperatura temperatura NNP cord-005646-xhx9pzhj 2361 10 /Lanser /Lanser . cord-005646-xhx9pzhj 2361 11 scheme/ scheme/ NNS cord-005646-xhx9pzhj 2361 12 for for IN cord-005646-xhx9pzhj 2361 13 72 72 CD cord-005646-xhx9pzhj 2361 14 - - SYM cord-005646-xhx9pzhj 2361 15 96 96 CD cord-005646-xhx9pzhj 2361 16 hours hour NNS cord-005646-xhx9pzhj 2361 17 . . . cord-005646-xhx9pzhj 2362 1 Another another DT cord-005646-xhx9pzhj 2362 2 ten ten CD cord-005646-xhx9pzhj 2362 3 septic septic JJ cord-005646-xhx9pzhj 2362 4 patients patient NNS cord-005646-xhx9pzhj 2362 5 /control /control . cord-005646-xhx9pzhj 2362 6 - - HYPH cord-005646-xhx9pzhj 2362 7 group group NN cord-005646-xhx9pzhj 2362 8 II/ ii/ NN cord-005646-xhx9pzhj 2363 1 the the DT cord-005646-xhx9pzhj 2363 2 mean mean JJ cord-005646-xhx9pzhj 2363 3 age age NN cord-005646-xhx9pzhj 2364 1 2,5 2,5 CD cord-005646-xhx9pzhj 2364 2 years year NNS cord-005646-xhx9pzhj 2364 3 / / SYM cord-005646-xhx9pzhj 2364 4 SD sd NN cord-005646-xhx9pzhj 2364 5 : : : cord-005646-xhx9pzhj 2364 6 O,65/ o,65/ UH cord-005646-xhx9pzhj 2364 7 , , , cord-005646-xhx9pzhj 2364 8 their -PRON- PRP$ cord-005646-xhx9pzhj 2364 9 blood blood NN cord-005646-xhx9pzhj 2364 10 cultures culture NNS cord-005646-xhx9pzhj 2364 11 were be VBD cord-005646-xhx9pzhj 2364 12 Gramm Gramm NNP cord-005646-xhx9pzhj 2364 13 negative negative JJ cord-005646-xhx9pzhj 2364 14 bacteria bacteria NNS cord-005646-xhx9pzhj 2364 15 6 6 CD cord-005646-xhx9pzhj 2364 16 , , , cord-005646-xhx9pzhj 2364 17 positive positive JJ cord-005646-xhx9pzhj 2364 18 2 2 CD cord-005646-xhx9pzhj 2364 19 , , , cord-005646-xhx9pzhj 2364 20 and and CC cord-005646-xhx9pzhj 2364 21 the the DT cord-005646-xhx9pzhj 2364 22 bacteria bacteria NNS cord-005646-xhx9pzhj 2364 23 was be VBD cord-005646-xhx9pzhj 2364 24 not not RB cord-005646-xhx9pzhj 2364 25 indentified indentifie VBN cord-005646-xhx9pzhj 2364 26 in in IN cord-005646-xhx9pzhj 2364 27 two two CD cord-005646-xhx9pzhj 2364 28 cases case NNS cord-005646-xhx9pzhj 2364 29 -were -were RBR cord-005646-xhx9pzhj 2364 30 treated treat VBN cord-005646-xhx9pzhj 2364 31 with with IN cord-005646-xhx9pzhj 2364 32 only only RB cord-005646-xhx9pzhj 2364 33 the the DT cord-005646-xhx9pzhj 2364 34 basis basis NN cord-005646-xhx9pzhj 2364 35 therapy therapy NN cord-005646-xhx9pzhj 2364 36 . . . cord-005646-xhx9pzhj 2365 1 Results result NNS cord-005646-xhx9pzhj 2365 2 : : : cord-005646-xhx9pzhj 2365 3 the the DT cord-005646-xhx9pzhj 2365 4 duration duration NN cord-005646-xhx9pzhj 2365 5 of of IN cord-005646-xhx9pzhj 2365 6 intensive intensive JJ cord-005646-xhx9pzhj 2365 7 treatment treatment NN cord-005646-xhx9pzhj 2365 8 decreased decrease VBD cord-005646-xhx9pzhj 2365 9 from from IN cord-005646-xhx9pzhj 2365 10 an an DT cord-005646-xhx9pzhj 2365 11 average average JJ cord-005646-xhx9pzhj 2365 12 22,7 22,7 CD cord-005646-xhx9pzhj 2365 13 days day NNS cord-005646-xhx9pzhj 2366 1 /SD:8 /SD:8 NNP cord-005646-xhx9pzhj 2366 2 , , , cord-005646-xhx9pzhj 2367 1 min min NNP cord-005646-xhx9pzhj 2367 2 12-max 12-max CD cord-005646-xhx9pzhj 2367 3 38 38 CD cord-005646-xhx9pzhj 2367 4 days/ days/ CD cord-005646-xhx9pzhj 2367 5 to to IN cord-005646-xhx9pzhj 2367 6 19,5 19,5 CD cord-005646-xhx9pzhj 2367 7 days day NNS cord-005646-xhx9pzhj 2368 1 /SD:5,2 /sd:5,2 NN cord-005646-xhx9pzhj 2368 2 min min NNP cord-005646-xhx9pzhj 2368 3 9-max 9-max VBD cord-005646-xhx9pzhj 2368 4 25 25 CD cord-005646-xhx9pzhj 2369 1 days/ days/ CD cord-005646-xhx9pzhj 2369 2 in in IN cord-005646-xhx9pzhj 2369 3 the the DT cord-005646-xhx9pzhj 2369 4 group group NN cord-005646-xhx9pzhj 2369 5 treated treat VBD cord-005646-xhx9pzhj 2369 6 wit wit NN cord-005646-xhx9pzhj 2369 7 Pentaglobin Pentaglobin NNP cord-005646-xhx9pzhj 2369 8 . . . cord-005646-xhx9pzhj 2370 1 The the DT cord-005646-xhx9pzhj 2370 2 difference difference NN cord-005646-xhx9pzhj 2370 3 was be VBD cord-005646-xhx9pzhj 2370 4 significant significant JJ cord-005646-xhx9pzhj 2370 5 /X /x NN cord-005646-xhx9pzhj 2370 6 2 2 CD cord-005646-xhx9pzhj 2370 7 p<0,01/. p<0,01/. NN cord-005646-xhx9pzhj 2371 1 In in IN cord-005646-xhx9pzhj 2371 2 the the DT cord-005646-xhx9pzhj 2371 3 group group NN cord-005646-xhx9pzhj 2371 4 I -PRON- PRP cord-005646-xhx9pzhj 2371 5 nobody nobody NN cord-005646-xhx9pzhj 2371 6 died die VBD cord-005646-xhx9pzhj 2371 7 , , , cord-005646-xhx9pzhj 2371 8 but but CC cord-005646-xhx9pzhj 2371 9 three three CD cord-005646-xhx9pzhj 2371 10 in in IN cord-005646-xhx9pzhj 2371 11 the the DT cord-005646-xhx9pzhj 2371 12 group group NN cord-005646-xhx9pzhj 2371 13 II II NNP cord-005646-xhx9pzhj 2371 14 . . . cord-005646-xhx9pzhj 2372 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2372 2 : : : cord-005646-xhx9pzhj 2372 3 the the DT cord-005646-xhx9pzhj 2372 4 Pentaglobin Pentaglobin NNP cord-005646-xhx9pzhj 2372 5 therapy therapy NN cord-005646-xhx9pzhj 2372 6 can can MD cord-005646-xhx9pzhj 2372 7 improve improve VB cord-005646-xhx9pzhj 2372 8 the the DT cord-005646-xhx9pzhj 2372 9 efficacy efficacy NN cord-005646-xhx9pzhj 2372 10 of of IN cord-005646-xhx9pzhj 2372 11 the the DT cord-005646-xhx9pzhj 2372 12 basis basis NN cord-005646-xhx9pzhj 2372 13 therapy therapy NN cord-005646-xhx9pzhj 2372 14 of of IN cord-005646-xhx9pzhj 2372 15 sepsis sepsis NN cord-005646-xhx9pzhj 2372 16 . . . cord-005646-xhx9pzhj 2373 1 Sinus sinus NN cord-005646-xhx9pzhj 2373 2 bradycardia bradycardia NN cord-005646-xhx9pzhj 2373 3 after after IN cord-005646-xhx9pzhj 2373 4 an an DT cord-005646-xhx9pzhj 2373 5 episode episode NN cord-005646-xhx9pzhj 2373 6 of of IN cord-005646-xhx9pzhj 2373 7 sepsis sepsis NN cord-005646-xhx9pzhj 2373 8 is be VBZ cord-005646-xhx9pzhj 2373 9 a a DT cord-005646-xhx9pzhj 2373 10 rare rare JJ cord-005646-xhx9pzhj 2373 11 symptom symptom NN cord-005646-xhx9pzhj 2373 12 complex complex NN cord-005646-xhx9pzhj 2373 13 decribed decribe VBD cord-005646-xhx9pzhj 2373 14 in in IN cord-005646-xhx9pzhj 2373 15 children child NNS cord-005646-xhx9pzhj 2373 16 with with IN cord-005646-xhx9pzhj 2373 17 hematologic hematologic JJ cord-005646-xhx9pzhj 2373 18 malignancies malignancy NNS cord-005646-xhx9pzhj 2373 19 . . . cord-005646-xhx9pzhj 2374 1 We -PRON- PRP cord-005646-xhx9pzhj 2374 2 present present VBP cord-005646-xhx9pzhj 2374 3 a a DT cord-005646-xhx9pzhj 2374 4 case case NN cord-005646-xhx9pzhj 2374 5 of of IN cord-005646-xhx9pzhj 2374 6 postsepsis postsepsis NN cord-005646-xhx9pzhj 2374 7 bradycardia bradycardia NN cord-005646-xhx9pzhj 2374 8 following follow VBG cord-005646-xhx9pzhj 2374 9 severe severe JJ cord-005646-xhx9pzhj 2374 10 typhlitis typhlitis JJ cord-005646-xhx9pzhj 2374 11 and and CC cord-005646-xhx9pzhj 2374 12 septic septic JJ cord-005646-xhx9pzhj 2374 13 shock shock NN cord-005646-xhx9pzhj 2374 14 in in IN cord-005646-xhx9pzhj 2374 15 a a DT cord-005646-xhx9pzhj 2374 16 12 12 CD cord-005646-xhx9pzhj 2374 17 year year NN cord-005646-xhx9pzhj 2374 18 old old JJ cord-005646-xhx9pzhj 2374 19 boy boy NN cord-005646-xhx9pzhj 2374 20 with with IN cord-005646-xhx9pzhj 2374 21 relapse relapse NN cord-005646-xhx9pzhj 2374 22 common common JJ cord-005646-xhx9pzhj 2374 23 ALL all DT cord-005646-xhx9pzhj 2374 24 . . . cord-005646-xhx9pzhj 2375 1 Blood blood NN cord-005646-xhx9pzhj 2375 2 and and CC cord-005646-xhx9pzhj 2375 3 ascitic ascitic JJ cord-005646-xhx9pzhj 2375 4 fluid fluid NN cord-005646-xhx9pzhj 2375 5 specimen specimen NN cord-005646-xhx9pzhj 2375 6 grew grow VBD cord-005646-xhx9pzhj 2375 7 Clostridium clostridium NN cord-005646-xhx9pzhj 2375 8 species specie NNS cord-005646-xhx9pzhj 2375 9 and and CC cord-005646-xhx9pzhj 2375 10 Pseudomonas Pseudomonas NNP cord-005646-xhx9pzhj 2375 11 aeruginosa aeruginosa NN cord-005646-xhx9pzhj 2375 12 . . . cord-005646-xhx9pzhj 2376 1 At at IN cord-005646-xhx9pzhj 2376 2 surgery surgery NN cord-005646-xhx9pzhj 2376 3 there there EX cord-005646-xhx9pzhj 2376 4 was be VBD cord-005646-xhx9pzhj 2376 5 a a DT cord-005646-xhx9pzhj 2376 6 necrotic necrotic JJ cord-005646-xhx9pzhj 2376 7 gangrenous gangrenous JJ cord-005646-xhx9pzhj 2376 8 terminal terminal JJ cord-005646-xhx9pzhj 2376 9 ileum ileum NN cord-005646-xhx9pzhj 2376 10 and and CC cord-005646-xhx9pzhj 2376 11 cecum cecum NN cord-005646-xhx9pzhj 2376 12 , , , cord-005646-xhx9pzhj 2376 13 requiring require VBG cord-005646-xhx9pzhj 2376 14 ileocecal ileocecal JJ cord-005646-xhx9pzhj 2376 15 bowel bowel NN cord-005646-xhx9pzhj 2376 16 resection resection NN cord-005646-xhx9pzhj 2376 17 with with IN cord-005646-xhx9pzhj 2376 18 ileostoma ileostoma NNP cord-005646-xhx9pzhj 2376 19 . . . cord-005646-xhx9pzhj 2377 1 While while IN cord-005646-xhx9pzhj 2377 2 clinically clinically RB cord-005646-xhx9pzhj 2377 3 recovering recover VBG cord-005646-xhx9pzhj 2377 4 from from IN cord-005646-xhx9pzhj 2377 5 sepsis sepsis NN cord-005646-xhx9pzhj 2377 6 he -PRON- PRP cord-005646-xhx9pzhj 2377 7 developed develop VBD cord-005646-xhx9pzhj 2377 8 bradycardia bradycardia NN cord-005646-xhx9pzhj 2377 9 for for IN cord-005646-xhx9pzhj 2377 10 120 120 CD cord-005646-xhx9pzhj 2377 11 hours hour NNS cord-005646-xhx9pzhj 2377 12 . . . cord-005646-xhx9pzhj 2378 1 Extensive extensive JJ cord-005646-xhx9pzhj 2378 2 diagnositic diagnositic JJ cord-005646-xhx9pzhj 2378 3 procedures procedure NNS cord-005646-xhx9pzhj 2378 4 was be VBD cord-005646-xhx9pzhj 2378 5 given give VBN cord-005646-xhx9pzhj 2378 6 and and CC cord-005646-xhx9pzhj 2378 7 the the DT cord-005646-xhx9pzhj 2378 8 heart heart NN cord-005646-xhx9pzhj 2378 9 rate rate NN cord-005646-xhx9pzhj 2378 10 slowly slowly RB cord-005646-xhx9pzhj 2378 11 increased increase VBD cord-005646-xhx9pzhj 2378 12 to to IN cord-005646-xhx9pzhj 2378 13 normal normal JJ cord-005646-xhx9pzhj 2378 14 range range NN cord-005646-xhx9pzhj 2378 15 of of IN cord-005646-xhx9pzhj 2378 16 age age NN cord-005646-xhx9pzhj 2378 17 . . . cord-005646-xhx9pzhj 2379 1 Postsepsis postsepsis NN cord-005646-xhx9pzhj 2379 2 bradycardia bradycardia NN cord-005646-xhx9pzhj 2379 3 in in IN cord-005646-xhx9pzhj 2379 4 children child NNS cord-005646-xhx9pzhj 2379 5 with with IN cord-005646-xhx9pzhj 2379 6 hematologic hematologic JJ cord-005646-xhx9pzhj 2379 7 malignancies malignancy NNS cord-005646-xhx9pzhj 2379 8 after after IN cord-005646-xhx9pzhj 2379 9 an an DT cord-005646-xhx9pzhj 2379 10 episode episode NN cord-005646-xhx9pzhj 2379 11 of of IN cord-005646-xhx9pzhj 2379 12 sepsis sepsis NN cord-005646-xhx9pzhj 2379 13 is be VBZ cord-005646-xhx9pzhj 2379 14 self self NN cord-005646-xhx9pzhj 2379 15 - - HYPH cord-005646-xhx9pzhj 2379 16 limiting limit VBG cord-005646-xhx9pzhj 2379 17 and and CC cord-005646-xhx9pzhj 2379 18 after after IN cord-005646-xhx9pzhj 2379 19 careful careful JJ cord-005646-xhx9pzhj 2379 20 differential differential JJ cord-005646-xhx9pzhj 2379 21 diagnostics diagnostic NNS cord-005646-xhx9pzhj 2379 22 warrants warrant NNS cord-005646-xhx9pzhj 2379 23 an an DT cord-005646-xhx9pzhj 2379 24 expectative expectative JJ cord-005646-xhx9pzhj 2379 25 attitude attitude NN cord-005646-xhx9pzhj 2379 26 . . . cord-005646-xhx9pzhj 2380 1 Nitrate nitrate NN cord-005646-xhx9pzhj 2380 2 level level NN cord-005646-xhx9pzhj 2380 3 is be VBZ cord-005646-xhx9pzhj 2380 4 known know VBN cord-005646-xhx9pzhj 2380 5 to to TO cord-005646-xhx9pzhj 2380 6 be be VB cord-005646-xhx9pzhj 2380 7 enhanced enhance VBN cord-005646-xhx9pzhj 2380 8 during during IN cord-005646-xhx9pzhj 2380 9 sepsis sepsis NN cord-005646-xhx9pzhj 2380 10 . . . cord-005646-xhx9pzhj 2381 1 Serum serum NN cord-005646-xhx9pzhj 2381 2 nitrate nitrate NN cord-005646-xhx9pzhj 2381 3 is be VBZ cord-005646-xhx9pzhj 2381 4 the the DT cord-005646-xhx9pzhj 2381 5 stable stable JJ cord-005646-xhx9pzhj 2381 6 metabolic metabolic JJ cord-005646-xhx9pzhj 2381 7 end end NN cord-005646-xhx9pzhj 2381 8 - - HYPH cord-005646-xhx9pzhj 2381 9 product product NN cord-005646-xhx9pzhj 2381 10 of of IN cord-005646-xhx9pzhj 2381 11 endogenous endogenous JJ cord-005646-xhx9pzhj 2381 12 nitric nitric NN cord-005646-xhx9pzhj 2381 13 oxide oxide NN cord-005646-xhx9pzhj 2381 14 generation generation NN cord-005646-xhx9pzhj 2381 15 . . . cord-005646-xhx9pzhj 2382 1 Nitric nitric NN cord-005646-xhx9pzhj 2382 2 oxide oxide NN cord-005646-xhx9pzhj 2382 3 has have VBZ cord-005646-xhx9pzhj 2382 4 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2382 5 to to TO cord-005646-xhx9pzhj 2382 6 be be VB cord-005646-xhx9pzhj 2382 7 a a DT cord-005646-xhx9pzhj 2382 8 powerful powerful JJ cord-005646-xhx9pzhj 2382 9 anti anti AFX cord-005646-xhx9pzhj 2382 10 microbial microbial JJ cord-005646-xhx9pzhj 2382 11 final final JJ cord-005646-xhx9pzhj 2382 12 mediator mediator NN cord-005646-xhx9pzhj 2382 13 and and CC cord-005646-xhx9pzhj 2382 14 also also RB cord-005646-xhx9pzhj 2382 15 a a DT cord-005646-xhx9pzhj 2382 16 key key JJ cord-005646-xhx9pzhj 2382 17 molecule molecule NN cord-005646-xhx9pzhj 2382 18 driving drive VBG cord-005646-xhx9pzhj 2382 19 to to IN cord-005646-xhx9pzhj 2382 20 the the DT cord-005646-xhx9pzhj 2382 21 lethality lethality NN cord-005646-xhx9pzhj 2382 22 of of IN cord-005646-xhx9pzhj 2382 23 one one CD cord-005646-xhx9pzhj 2382 24 of of IN cord-005646-xhx9pzhj 2382 25 the the DT cord-005646-xhx9pzhj 2382 26 most most RBS cord-005646-xhx9pzhj 2382 27 common common JJ cord-005646-xhx9pzhj 2382 28 complication complication NN cord-005646-xhx9pzhj 2382 29 of of IN cord-005646-xhx9pzhj 2382 30 sepsis sepsis NN cord-005646-xhx9pzhj 2382 31 ; ; : cord-005646-xhx9pzhj 2382 32 the the DT cord-005646-xhx9pzhj 2382 33 endotoxic endotoxic JJ cord-005646-xhx9pzhj 2382 34 shock shock NN cord-005646-xhx9pzhj 2382 35 . . . cord-005646-xhx9pzhj 2383 1 Such such JJ cord-005646-xhx9pzhj 2383 2 facts fact NNS cord-005646-xhx9pzhj 2383 3 prompted prompt VBD cord-005646-xhx9pzhj 2383 4 us -PRON- PRP cord-005646-xhx9pzhj 2383 5 to to TO cord-005646-xhx9pzhj 2383 6 investigate investigate VB cord-005646-xhx9pzhj 2383 7 the the DT cord-005646-xhx9pzhj 2383 8 possible possible JJ cord-005646-xhx9pzhj 2383 9 diagnostic diagnostic JJ cord-005646-xhx9pzhj 2383 10 and/or and/or CC cord-005646-xhx9pzhj 2383 11 prognostic prognostic JJ cord-005646-xhx9pzhj 2383 12 value value NN cord-005646-xhx9pzhj 2383 13 of of IN cord-005646-xhx9pzhj 2383 14 monitoring monitor VBG cord-005646-xhx9pzhj 2383 15 serum serum NN cord-005646-xhx9pzhj 2383 16 level level NN cord-005646-xhx9pzhj 2383 17 in in IN cord-005646-xhx9pzhj 2383 18 high high JJ cord-005646-xhx9pzhj 2383 19 risk risk NN cord-005646-xhx9pzhj 2383 20 , , , cord-005646-xhx9pzhj 2383 21 presumptive presumptive JJ cord-005646-xhx9pzhj 2383 22 and and CC cord-005646-xhx9pzhj 2383 23 confirmed confirm VBD cord-005646-xhx9pzhj 2383 24 sepsis sepsis NN cord-005646-xhx9pzhj 2383 25 patients patient NNS cord-005646-xhx9pzhj 2383 26 . . . cord-005646-xhx9pzhj 2384 1 Additionally additionally RB cord-005646-xhx9pzhj 2384 2 we -PRON- PRP cord-005646-xhx9pzhj 2384 3 have have VBP cord-005646-xhx9pzhj 2384 4 explored explore VBN cord-005646-xhx9pzhj 2384 5 the the DT cord-005646-xhx9pzhj 2384 6 usefulness usefulness NN cord-005646-xhx9pzhj 2384 7 of of IN cord-005646-xhx9pzhj 2384 8 this this DT cord-005646-xhx9pzhj 2384 9 mediator mediator NN cord-005646-xhx9pzhj 2384 10 as as IN cord-005646-xhx9pzhj 2384 11 index index NN cord-005646-xhx9pzhj 2384 12 of of IN cord-005646-xhx9pzhj 2384 13 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2384 14 response response NN cord-005646-xhx9pzhj 2384 15 . . . cord-005646-xhx9pzhj 2385 1 In in IN cord-005646-xhx9pzhj 2385 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2385 3 study study NN cord-005646-xhx9pzhj 2385 4 it -PRON- PRP cord-005646-xhx9pzhj 2385 5 is be VBZ cord-005646-xhx9pzhj 2385 6 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2385 7 that that IN cord-005646-xhx9pzhj 2385 8 there there EX cord-005646-xhx9pzhj 2385 9 is be VBZ cord-005646-xhx9pzhj 2385 10 an an DT cord-005646-xhx9pzhj 2385 11 important important JJ cord-005646-xhx9pzhj 2385 12 relationship relationship NN cord-005646-xhx9pzhj 2385 13 between between IN cord-005646-xhx9pzhj 2385 14 nitrate nitrate NN cord-005646-xhx9pzhj 2385 15 level level NN cord-005646-xhx9pzhj 2385 16 and and CC cord-005646-xhx9pzhj 2385 17 the the DT cord-005646-xhx9pzhj 2385 18 occurrence occurrence NN cord-005646-xhx9pzhj 2385 19 of of IN cord-005646-xhx9pzhj 2385 20 neonatal neonatal JJ cord-005646-xhx9pzhj 2385 21 sepsis sepsis NN cord-005646-xhx9pzhj 2385 22 . . . cord-005646-xhx9pzhj 2386 1 Septic septic JJ cord-005646-xhx9pzhj 2386 2 newborn newborn JJ cord-005646-xhx9pzhj 2386 3 group group NN cord-005646-xhx9pzhj 2386 4 showed show VBD cord-005646-xhx9pzhj 2386 5 6 6 CD cord-005646-xhx9pzhj 2386 6 fold fold VB cord-005646-xhx9pzhj 2386 7 higher high JJR cord-005646-xhx9pzhj 2386 8 nitrate nitrate NN cord-005646-xhx9pzhj 2386 9 level level NN cord-005646-xhx9pzhj 2386 10 than than IN cord-005646-xhx9pzhj 2386 11 that that DT cord-005646-xhx9pzhj 2386 12 of of IN cord-005646-xhx9pzhj 2386 13 healthy healthy JJ cord-005646-xhx9pzhj 2386 14 control control NN cord-005646-xhx9pzhj 2386 15 group group NN cord-005646-xhx9pzhj 2386 16 . . . cord-005646-xhx9pzhj 2387 1 In in IN cord-005646-xhx9pzhj 2387 2 addition addition NN cord-005646-xhx9pzhj 2387 3 , , , cord-005646-xhx9pzhj 2387 4 the the DT cord-005646-xhx9pzhj 2387 5 group group NN cord-005646-xhx9pzhj 2387 6 of of IN cord-005646-xhx9pzhj 2387 7 patients patient NNS cord-005646-xhx9pzhj 2387 8 with with IN cord-005646-xhx9pzhj 2387 9 high high JJ cord-005646-xhx9pzhj 2387 10 risk risk NN cord-005646-xhx9pzhj 2387 11 of of IN cord-005646-xhx9pzhj 2387 12 sepsis sepsis NN cord-005646-xhx9pzhj 2387 13 which which WDT cord-005646-xhx9pzhj 2387 14 finally finally RB cord-005646-xhx9pzhj 2387 15 became become VBD cord-005646-xhx9pzhj 2387 16 septics septic NNS cord-005646-xhx9pzhj 2387 17 , , , cord-005646-xhx9pzhj 2387 18 exhibited exhibit VBD cord-005646-xhx9pzhj 2387 19 3 3 CD cord-005646-xhx9pzhj 2387 20 fold fold VBP cord-005646-xhx9pzhj 2387 21 higher high JJR cord-005646-xhx9pzhj 2387 22 nitrate nitrate NN cord-005646-xhx9pzhj 2387 23 level level NN cord-005646-xhx9pzhj 2387 24 at at IN cord-005646-xhx9pzhj 2387 25 24 24 CD cord-005646-xhx9pzhj 2387 26 - - SYM cord-005646-xhx9pzhj 2387 27 72 72 CD cord-005646-xhx9pzhj 2387 28 hours hour NNS cord-005646-xhx9pzhj 2387 29 before before IN cord-005646-xhx9pzhj 2387 30 the the DT cord-005646-xhx9pzhj 2387 31 first first JJ cord-005646-xhx9pzhj 2387 32 symptoms symptom NNS cord-005646-xhx9pzhj 2387 33 appeared appear VBD cord-005646-xhx9pzhj 2387 34 , , , cord-005646-xhx9pzhj 2387 35 when when WRB cord-005646-xhx9pzhj 2387 36 compare compare VBP cord-005646-xhx9pzhj 2387 37 with with IN cord-005646-xhx9pzhj 2387 38 those those DT cord-005646-xhx9pzhj 2387 39 who who WP cord-005646-xhx9pzhj 2387 40 did do VBD cord-005646-xhx9pzhj 2387 41 not not RB cord-005646-xhx9pzhj 2387 42 develop develop VB cord-005646-xhx9pzhj 2387 43 sepsis sepsis NN cord-005646-xhx9pzhj 2387 44 . . . cord-005646-xhx9pzhj 2388 1 However however RB cord-005646-xhx9pzhj 2388 2 in in IN cord-005646-xhx9pzhj 2388 3 the the DT cord-005646-xhx9pzhj 2388 4 presumptive presumptive JJ cord-005646-xhx9pzhj 2388 5 sepsis sepsis NN cord-005646-xhx9pzhj 2388 6 group group NN cord-005646-xhx9pzhj 2388 7 , , , cord-005646-xhx9pzhj 2388 8 there there EX cord-005646-xhx9pzhj 2388 9 was be VBD cord-005646-xhx9pzhj 2388 10 no no DT cord-005646-xhx9pzhj 2388 11 difference difference NN cord-005646-xhx9pzhj 2388 12 between between IN cord-005646-xhx9pzhj 2388 13 the the DT cord-005646-xhx9pzhj 2388 14 patients patient NNS cord-005646-xhx9pzhj 2388 15 which which WDT cord-005646-xhx9pzhj 2388 16 finalIy finalIy NNP cord-005646-xhx9pzhj 2388 17 , , , cord-005646-xhx9pzhj 2388 18 & & CC cord-005646-xhx9pzhj 2388 19 ' ' `` cord-005646-xhx9pzhj 2388 20 ere ere VBP cord-005646-xhx9pzhj 2388 21 considered consider VBN cord-005646-xhx9pzhj 2388 22 septics septic NNS cord-005646-xhx9pzhj 2388 23 and and CC cord-005646-xhx9pzhj 2388 24 those those DT cord-005646-xhx9pzhj 2388 25 which which WDT cord-005646-xhx9pzhj 2388 26 not not RB cord-005646-xhx9pzhj 2388 27 . . . cord-005646-xhx9pzhj 2389 1 In in IN cord-005646-xhx9pzhj 2389 2 all all DT cord-005646-xhx9pzhj 2389 3 septic septic JJ cord-005646-xhx9pzhj 2389 4 cases case NNS cord-005646-xhx9pzhj 2389 5 , , , cord-005646-xhx9pzhj 2389 6 after after IN cord-005646-xhx9pzhj 2389 7 7 7 CD cord-005646-xhx9pzhj 2389 8 days day NNS cord-005646-xhx9pzhj 2389 9 of of IN cord-005646-xhx9pzhj 2389 10 a a DT cord-005646-xhx9pzhj 2389 11 successful successful JJ cord-005646-xhx9pzhj 2389 12 therapy therapy NN cord-005646-xhx9pzhj 2389 13 with with IN cord-005646-xhx9pzhj 2389 14 antibiotics antibiotic NNS cord-005646-xhx9pzhj 2389 15 , , , cord-005646-xhx9pzhj 2389 16 the the DT cord-005646-xhx9pzhj 2389 17 level level NN cord-005646-xhx9pzhj 2389 18 of of IN cord-005646-xhx9pzhj 2389 19 nitrate nitrate NN cord-005646-xhx9pzhj 2389 20 diminish diminish NN cord-005646-xhx9pzhj 2389 21 3 3 CD cord-005646-xhx9pzhj 2389 22 fold fold NN cord-005646-xhx9pzhj 2389 23 . . . cord-005646-xhx9pzhj 2390 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 2390 2 results result NNS cord-005646-xhx9pzhj 2390 3 suggest suggest VBP cord-005646-xhx9pzhj 2390 4 the the DT cord-005646-xhx9pzhj 2390 5 utility utility NN cord-005646-xhx9pzhj 2390 6 of of IN cord-005646-xhx9pzhj 2390 7 monitoring monitor VBG cord-005646-xhx9pzhj 2390 8 nitrate nitrate NN cord-005646-xhx9pzhj 2390 9 as as IN cord-005646-xhx9pzhj 2390 10 index index NN cord-005646-xhx9pzhj 2390 11 for for IN cord-005646-xhx9pzhj 2390 12 the the DT cord-005646-xhx9pzhj 2390 13 diagnosis diagnosis NN cord-005646-xhx9pzhj 2390 14 of of IN cord-005646-xhx9pzhj 2390 15 neonatal neonatal JJ cord-005646-xhx9pzhj 2390 16 sepsis sepsis NN cord-005646-xhx9pzhj 2390 17 . . . cord-005646-xhx9pzhj 2391 1 The the DT cord-005646-xhx9pzhj 2391 2 potential potential JJ cord-005646-xhx9pzhj 2391 3 benefits benefit NNS cord-005646-xhx9pzhj 2391 4 of of IN cord-005646-xhx9pzhj 2391 5 exchange exchange NN cord-005646-xhx9pzhj 2391 6 transfusion transfusion NN cord-005646-xhx9pzhj 2391 7 , , , cord-005646-xhx9pzhj 2391 8 plasma plasma NN cord-005646-xhx9pzhj 2391 9 exchange exchange NN cord-005646-xhx9pzhj 2391 10 , , , cord-005646-xhx9pzhj 2391 11 and and CC cord-005646-xhx9pzhj 2391 12 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 2391 13 have have VBP cord-005646-xhx9pzhj 2391 14 all all DT cord-005646-xhx9pzhj 2391 15 been be VBN cord-005646-xhx9pzhj 2391 16 described describe VBN cord-005646-xhx9pzhj 2391 17 in in IN cord-005646-xhx9pzhj 2391 18 children child NNS cord-005646-xhx9pzhj 2391 19 with with IN cord-005646-xhx9pzhj 2391 20 overwhelming overwhelming JJ cord-005646-xhx9pzhj 2391 21 sepsis sepsis NN cord-005646-xhx9pzhj 2391 22 . . . cord-005646-xhx9pzhj 2392 1 However however RB cord-005646-xhx9pzhj 2392 2 , , , cord-005646-xhx9pzhj 2392 3 little little JJ cord-005646-xhx9pzhj 2392 4 hard hard JJ cord-005646-xhx9pzhj 2392 5 evidence evidence NN cord-005646-xhx9pzhj 2392 6 exists exist VBZ cord-005646-xhx9pzhj 2392 7 to to TO cord-005646-xhx9pzhj 2392 8 prove prove VB cord-005646-xhx9pzhj 2392 9 the the DT cord-005646-xhx9pzhj 2392 10 benefits benefit NNS cord-005646-xhx9pzhj 2392 11 of of IN cord-005646-xhx9pzhj 2392 12 any any DT cord-005646-xhx9pzhj 2392 13 of of IN cord-005646-xhx9pzhj 2392 14 these these DT cord-005646-xhx9pzhj 2392 15 techniques technique NNS cord-005646-xhx9pzhj 2392 16 . . . cord-005646-xhx9pzhj 2393 1 I -PRON- PRP cord-005646-xhx9pzhj 2393 2 have have VBP cord-005646-xhx9pzhj 2393 3 treated treat VBN cord-005646-xhx9pzhj 2393 4 five five CD cord-005646-xhx9pzhj 2393 5 patients patient NNS cord-005646-xhx9pzhj 2393 6 with with IN cord-005646-xhx9pzhj 2393 7 plasma plasma NN cord-005646-xhx9pzhj 2393 8 exchange exchange NN cord-005646-xhx9pzhj 2393 9 ( ( -LRB- cord-005646-xhx9pzhj 2393 10 PE PE NNP cord-005646-xhx9pzhj 2393 11 ) ) -RRB- cord-005646-xhx9pzhj 2393 12 , , , cord-005646-xhx9pzhj 2393 13 having have VBG cord-005646-xhx9pzhj 2393 14 been be VBN cord-005646-xhx9pzhj 2393 15 asked ask VBN cord-005646-xhx9pzhj 2393 16 to to TO cord-005646-xhx9pzhj 2393 17 see see VB cord-005646-xhx9pzhj 2393 18 all all PDT cord-005646-xhx9pzhj 2393 19 these these DT cord-005646-xhx9pzhj 2393 20 patients patient NNS cord-005646-xhx9pzhj 2393 21 at at IN cord-005646-xhx9pzhj 2393 22 a a DT cord-005646-xhx9pzhj 2393 23 point point NN cord-005646-xhx9pzhj 2393 24 when when WRB cord-005646-xhx9pzhj 2393 25 it -PRON- PRP cord-005646-xhx9pzhj 2393 26 was be VBD cord-005646-xhx9pzhj 2393 27 felt feel VBN cord-005646-xhx9pzhj 2393 28 death death NN cord-005646-xhx9pzhj 2393 29 was be VBD cord-005646-xhx9pzhj 2393 30 inevitable inevitable JJ cord-005646-xhx9pzhj 2393 31 . . . cord-005646-xhx9pzhj 2394 1 Two two CD cord-005646-xhx9pzhj 2394 2 of of IN cord-005646-xhx9pzhj 2394 3 the the DT cord-005646-xhx9pzhj 2394 4 patients patient NNS cord-005646-xhx9pzhj 2394 5 had have VBD cord-005646-xhx9pzhj 2394 6 staphylococcal staphylococcal JJ cord-005646-xhx9pzhj 2394 7 , , , cord-005646-xhx9pzhj 2394 8 two two CD cord-005646-xhx9pzhj 2394 9 meningococcal meningococcal JJ cord-005646-xhx9pzhj 2394 10 and and CC cord-005646-xhx9pzhj 2394 11 one one CD cord-005646-xhx9pzhj 2394 12 enterococcal enterococcal JJ cord-005646-xhx9pzhj 2394 13 septicaemia septicaemia NN cord-005646-xhx9pzhj 2394 14 . . . cord-005646-xhx9pzhj 2395 1 All all DT cord-005646-xhx9pzhj 2395 2 patients patient NNS cord-005646-xhx9pzhj 2395 3 showed show VBD cord-005646-xhx9pzhj 2395 4 a a DT cord-005646-xhx9pzhj 2395 5 dramatic dramatic JJ cord-005646-xhx9pzhj 2395 6 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 2395 7 improvement improvement NN cord-005646-xhx9pzhj 2395 8 following follow VBG cord-005646-xhx9pzhj 2395 9 PE PE NNP cord-005646-xhx9pzhj 2395 10 with with IN cord-005646-xhx9pzhj 2395 11 improvement improvement NN cord-005646-xhx9pzhj 2395 12 in in IN cord-005646-xhx9pzhj 2395 13 blood blood NN cord-005646-xhx9pzhj 2395 14 pressure pressure NN cord-005646-xhx9pzhj 2395 15 , , , cord-005646-xhx9pzhj 2395 16 reduction reduction NN cord-005646-xhx9pzhj 2395 17 in in IN cord-005646-xhx9pzhj 2395 18 inotrope inotrope NN cord-005646-xhx9pzhj 2395 19 requirement requirement NN cord-005646-xhx9pzhj 2395 20 and and CC cord-005646-xhx9pzhj 2395 21 improvement improvement NN cord-005646-xhx9pzhj 2395 22 in in IN cord-005646-xhx9pzhj 2395 23 tissue tissue NN cord-005646-xhx9pzhj 2395 24 perfusion perfusion NN cord-005646-xhx9pzhj 2395 25 . . . cord-005646-xhx9pzhj 2396 1 Three three CD cord-005646-xhx9pzhj 2396 2 patients patient NNS cord-005646-xhx9pzhj 2396 3 survived survive VBD cord-005646-xhx9pzhj 2396 4 . . . cord-005646-xhx9pzhj 2397 1 One one CD cord-005646-xhx9pzhj 2397 2 of of IN cord-005646-xhx9pzhj 2397 3 the the DT cord-005646-xhx9pzhj 2397 4 patients patient NNS cord-005646-xhx9pzhj 2397 5 with with IN cord-005646-xhx9pzhj 2397 6 staphylococcal staphylococcal JJ cord-005646-xhx9pzhj 2397 7 sepsis sepsis NN cord-005646-xhx9pzhj 2397 8 and and CC cord-005646-xhx9pzhj 2397 9 both both DT cord-005646-xhx9pzhj 2397 10 of of IN cord-005646-xhx9pzhj 2397 11 the the DT cord-005646-xhx9pzhj 2397 12 patients patient NNS cord-005646-xhx9pzhj 2397 13 with with IN cord-005646-xhx9pzhj 2397 14 meningococeal meningococeal JJ cord-005646-xhx9pzhj 2397 15 sepsis sepsis NN cord-005646-xhx9pzhj 2397 16 had have VBD cord-005646-xhx9pzhj 2397 17 developing develop VBG cord-005646-xhx9pzhj 2397 18 gangrene gangrene NN cord-005646-xhx9pzhj 2397 19 of of IN cord-005646-xhx9pzhj 2397 20 the the DT cord-005646-xhx9pzhj 2397 21 limbs limb NNS cord-005646-xhx9pzhj 2397 22 which which WDT cord-005646-xhx9pzhj 2397 23 showed show VBD cord-005646-xhx9pzhj 2397 24 remarkable remarkable JJ cord-005646-xhx9pzhj 2397 25 reperfusion reperfusion NN cord-005646-xhx9pzhj 2397 26 with with IN cord-005646-xhx9pzhj 2397 27 PE PE NNP cord-005646-xhx9pzhj 2397 28 . . . cord-005646-xhx9pzhj 2398 1 In in IN cord-005646-xhx9pzhj 2398 2 two two CD cord-005646-xhx9pzhj 2398 3 of of IN cord-005646-xhx9pzhj 2398 4 the the DT cord-005646-xhx9pzhj 2398 5 patients patient NNS cord-005646-xhx9pzhj 2398 6 measurements measurement NNS cord-005646-xhx9pzhj 2398 7 of of IN cord-005646-xhx9pzhj 2398 8 cardiac cardiac JJ cord-005646-xhx9pzhj 2398 9 output output NN cord-005646-xhx9pzhj 2398 10 ( ( -LRB- cord-005646-xhx9pzhj 2398 11 CO co NN cord-005646-xhx9pzhj 2398 12 ) ) -RRB- cord-005646-xhx9pzhj 2398 13 and and CC cord-005646-xhx9pzhj 2398 14 systemic systemic JJ cord-005646-xhx9pzhj 2398 15 vascular vascular JJ cord-005646-xhx9pzhj 2398 16 resistance resistance NN cord-005646-xhx9pzhj 2398 17 ( ( -LRB- cord-005646-xhx9pzhj 2398 18 SVR SVR NNP cord-005646-xhx9pzhj 2398 19 ) ) -RRB- cord-005646-xhx9pzhj 2398 20 showed show VBD cord-005646-xhx9pzhj 2398 21 ~a ~a NNP cord-005646-xhx9pzhj 2398 22 reduction reduction NN cord-005646-xhx9pzhj 2398 23 in in IN cord-005646-xhx9pzhj 2398 24 CO CO NNP cord-005646-xhx9pzhj 2398 25 and and CC cord-005646-xhx9pzhj 2398 26 a a DT cord-005646-xhx9pzhj 2398 27 rise rise NN cord-005646-xhx9pzhj 2398 28 in in IN cord-005646-xhx9pzhj 2398 29 SVR SVR NNP cord-005646-xhx9pzhj 2398 30 over over IN cord-005646-xhx9pzhj 2398 31 the the DT cord-005646-xhx9pzhj 2398 32 course course NN cord-005646-xhx9pzhj 2398 33 of of IN cord-005646-xhx9pzhj 2398 34 a a DT cord-005646-xhx9pzhj 2398 35 PE PE NNP cord-005646-xhx9pzhj 2398 36 despite despite IN cord-005646-xhx9pzhj 2398 37 the the DT cord-005646-xhx9pzhj 2398 38 reduction reduction NN cord-005646-xhx9pzhj 2398 39 or or CC cord-005646-xhx9pzhj 2398 40 cessation cessation NN cord-005646-xhx9pzhj 2398 41 of of IN cord-005646-xhx9pzhj 2398 42 vasoconstricting vasoconstricting NNP cord-005646-xhx9pzhj 2398 43 inotropes inotropes NNP cord-005646-xhx9pzhj 2398 44 . . . cord-005646-xhx9pzhj 2399 1 Many many JJ cord-005646-xhx9pzhj 2399 2 believe believe VBP cord-005646-xhx9pzhj 2399 3 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 2399 4 is be VBZ cord-005646-xhx9pzhj 2399 5 of of IN cord-005646-xhx9pzhj 2399 6 value value NN cord-005646-xhx9pzhj 2399 7 in in IN cord-005646-xhx9pzhj 2399 8 septic septic JJ cord-005646-xhx9pzhj 2399 9 shock shock NN cord-005646-xhx9pzhj 2399 10 . . . cord-005646-xhx9pzhj 2400 1 A a DT cord-005646-xhx9pzhj 2400 2 trial trial NN cord-005646-xhx9pzhj 2400 3 with with IN cord-005646-xhx9pzhj 2400 4 a a DT cord-005646-xhx9pzhj 2400 5 no no DT cord-005646-xhx9pzhj 2400 6 treatment treatment NN cord-005646-xhx9pzhj 2400 7 limb limb NN cord-005646-xhx9pzhj 2400 8 is be VBZ cord-005646-xhx9pzhj 2400 9 difficult difficult JJ cord-005646-xhx9pzhj 2400 10 to to TO cord-005646-xhx9pzhj 2400 11 achieve achieve VB cord-005646-xhx9pzhj 2400 12 . . . cord-005646-xhx9pzhj 2401 1 I -PRON- PRP cord-005646-xhx9pzhj 2401 2 believe believe VBP cord-005646-xhx9pzhj 2401 3 we -PRON- PRP cord-005646-xhx9pzhj 2401 4 now now RB cord-005646-xhx9pzhj 2401 5 have have VBP cord-005646-xhx9pzhj 2401 6 enough enough JJ cord-005646-xhx9pzhj 2401 7 evidence evidence NN cord-005646-xhx9pzhj 2401 8 to to TO cord-005646-xhx9pzhj 2401 9 justify justify VB cord-005646-xhx9pzhj 2401 10 a a DT cord-005646-xhx9pzhj 2401 11 controlled control VBN cord-005646-xhx9pzhj 2401 12 trial trial NN cord-005646-xhx9pzhj 2401 13 of of IN cord-005646-xhx9pzhj 2401 14 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 2401 15 versus versus IN cord-005646-xhx9pzhj 2401 16 plasma plasma NNP cord-005646-xhx9pzhj 2401 17 exchange exchange NN cord-005646-xhx9pzhj 2401 18 in in IN cord-005646-xhx9pzhj 2401 19 patients patient NNS cord-005646-xhx9pzhj 2401 20 with with IN cord-005646-xhx9pzhj 2401 21 septic septic JJ cord-005646-xhx9pzhj 2401 22 shock shock NN cord-005646-xhx9pzhj 2401 23 and and CC cord-005646-xhx9pzhj 2401 24 unstable unstable JJ cord-005646-xhx9pzhj 2401 25 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 2401 26 status status NN cord-005646-xhx9pzhj 2401 27 whilst whilst IN cord-005646-xhx9pzhj 2401 28 on on IN cord-005646-xhx9pzhj 2401 29 inotropic inotropic NNP cord-005646-xhx9pzhj 2401 30 support support NN cord-005646-xhx9pzhj 2401 31 . . . cord-005646-xhx9pzhj 2401 32 _SP cord-005646-xhx9pzhj 2402 1 During during IN cord-005646-xhx9pzhj 2402 2 the the DT cord-005646-xhx9pzhj 2402 3 next next JJ cord-005646-xhx9pzhj 2402 4 several several JJ cord-005646-xhx9pzhj 2402 5 days day NNS cord-005646-xhx9pzhj 2402 6 , , , cord-005646-xhx9pzhj 2402 7 cough cough NN cord-005646-xhx9pzhj 2402 8 and and CC cord-005646-xhx9pzhj 2402 9 chest chest NN cord-005646-xhx9pzhj 2402 10 pain pain NN cord-005646-xhx9pzhj 2402 11 suggested suggest VBD cord-005646-xhx9pzhj 2402 12 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2402 13 embolism embolism NN cord-005646-xhx9pzhj 2402 14 confirmed confirm VBN cord-005646-xhx9pzhj 2402 15 by by IN cord-005646-xhx9pzhj 2402 16 radiologic radiologic JJ cord-005646-xhx9pzhj 2402 17 evaluation evaluation NN cord-005646-xhx9pzhj 2402 18 . . . cord-005646-xhx9pzhj 2403 1 Echocardiographic echocardiographic JJ cord-005646-xhx9pzhj 2403 2 examination examination NN cord-005646-xhx9pzhj 2403 3 showed show VBD cord-005646-xhx9pzhj 2403 4 multiple multiple JJ cord-005646-xhx9pzhj 2403 5 thrombosis thrombosis NN cord-005646-xhx9pzhj 2403 6 of of IN cord-005646-xhx9pzhj 2403 7 the the DT cord-005646-xhx9pzhj 2403 8 superior superior JJ cord-005646-xhx9pzhj 2403 9 vena vena FW cord-005646-xhx9pzhj 2403 10 cava cava NNP cord-005646-xhx9pzhj 2403 11 , , , cord-005646-xhx9pzhj 2403 12 right right JJ cord-005646-xhx9pzhj 2403 13 atrium atrium NN cord-005646-xhx9pzhj 2403 14 and and CC cord-005646-xhx9pzhj 2403 15 ventricle ventricle NN cord-005646-xhx9pzhj 2403 16 and and CC cord-005646-xhx9pzhj 2403 17 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2403 18 artery artery NN cord-005646-xhx9pzhj 2403 19 . . . cord-005646-xhx9pzhj 2404 1 Estimated estimate VBN cord-005646-xhx9pzhj 2404 2 protein protein NN cord-005646-xhx9pzhj 2404 3 C c NN cord-005646-xhx9pzhj 2404 4 level level NN cord-005646-xhx9pzhj 2404 5 was be VBD cord-005646-xhx9pzhj 2404 6 50.7 50.7 CD cord-005646-xhx9pzhj 2404 7 % % NN cord-005646-xhx9pzhj 2404 8 ( ( -LRB- cord-005646-xhx9pzhj 2404 9 nOrmal nOrmal NNP cord-005646-xhx9pzhj 2404 10 range range VBP cord-005646-xhx9pzhj 2404 11 70 70 CD cord-005646-xhx9pzhj 2404 12 - - SYM cord-005646-xhx9pzhj 2404 13 140 140 CD cord-005646-xhx9pzhj 2404 14 % % NN cord-005646-xhx9pzhj 2404 15 ) ) -RRB- cord-005646-xhx9pzhj 2404 16 ; ; , cord-005646-xhx9pzhj 2404 17 identical identical JJ cord-005646-xhx9pzhj 2404 18 deficiency deficiency NN cord-005646-xhx9pzhj 2404 19 was be VBD cord-005646-xhx9pzhj 2404 20 found find VBN cord-005646-xhx9pzhj 2404 21 in in IN cord-005646-xhx9pzhj 2404 22 patient patient NN cord-005646-xhx9pzhj 2404 23 's 's POS cord-005646-xhx9pzhj 2404 24 mother mother NN cord-005646-xhx9pzhj 2404 25 and and CC cord-005646-xhx9pzhj 2404 26 elder eld JJR cord-005646-xhx9pzhj 2404 27 sister sister NN cord-005646-xhx9pzhj 2404 28 . . . cord-005646-xhx9pzhj 2405 1 CVC CVC NNP cord-005646-xhx9pzhj 2405 2 was be VBD cord-005646-xhx9pzhj 2405 3 removed remove VBN cord-005646-xhx9pzhj 2405 4 , , , cord-005646-xhx9pzhj 2405 5 and and CC cord-005646-xhx9pzhj 2405 6 alter alter VB cord-005646-xhx9pzhj 2405 7 2-month 2-month JJ cord-005646-xhx9pzhj 2405 8 Heparin Heparin NNP cord-005646-xhx9pzhj 2405 9 therapy therapy NN cord-005646-xhx9pzhj 2405 10 and and CC cord-005646-xhx9pzhj 2405 11 supstitution supstitution NN cord-005646-xhx9pzhj 2405 12 OF of IN cord-005646-xhx9pzhj 2405 13 protein protein NN cord-005646-xhx9pzhj 2405 14 C c NN cord-005646-xhx9pzhj 2405 15 with with IN cord-005646-xhx9pzhj 2405 16 fresh fresh JJ cord-005646-xhx9pzhj 2405 17 frozen frozen JJ cord-005646-xhx9pzhj 2405 18 plasma plasma NN cord-005646-xhx9pzhj 2405 19 , , , cord-005646-xhx9pzhj 2405 20 there there EX cord-005646-xhx9pzhj 2405 21 was be VBD cord-005646-xhx9pzhj 2405 22 almost almost RB cord-005646-xhx9pzhj 2405 23 complete complete JJ cord-005646-xhx9pzhj 2405 24 thrombolysis thrombolysis NN cord-005646-xhx9pzhj 2405 25 of of IN cord-005646-xhx9pzhj 2405 26 the the DT cord-005646-xhx9pzhj 2405 27 great great JJ cord-005646-xhx9pzhj 2405 28 vessels vessel NNS cord-005646-xhx9pzhj 2405 29 and and CC cord-005646-xhx9pzhj 2405 30 cardiac cardiac JJ cord-005646-xhx9pzhj 2405 31 chambers chamber NNS cord-005646-xhx9pzhj 2405 32 . . . cord-005646-xhx9pzhj 2406 1 We -PRON- PRP cord-005646-xhx9pzhj 2406 2 conclude conclude VBP cord-005646-xhx9pzhj 2406 3 that that IN cord-005646-xhx9pzhj 2406 4 invasive invasive JJ cord-005646-xhx9pzhj 2406 5 diagnostic diagnostic JJ cord-005646-xhx9pzhj 2406 6 and and CC cord-005646-xhx9pzhj 2406 7 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2406 8 procedures procedure NNS cord-005646-xhx9pzhj 2406 9 in in IN cord-005646-xhx9pzhj 2406 10 such such JJ cord-005646-xhx9pzhj 2406 11 patients patient NNS cord-005646-xhx9pzhj 2406 12 may may MD cord-005646-xhx9pzhj 2406 13 result result VB cord-005646-xhx9pzhj 2406 14 in in IN cord-005646-xhx9pzhj 2406 15 higher high JJR cord-005646-xhx9pzhj 2406 16 risk risk NN cord-005646-xhx9pzhj 2406 17 for for IN cord-005646-xhx9pzhj 2406 18 severe severe JJ cord-005646-xhx9pzhj 2406 19 thrombosis thrombosis NN cord-005646-xhx9pzhj 2406 20 at at IN cord-005646-xhx9pzhj 2406 21 unusual unusual JJ cord-005646-xhx9pzhj 2406 22 sites site NNS cord-005646-xhx9pzhj 2406 23 , , , cord-005646-xhx9pzhj 2406 24 and and CC cord-005646-xhx9pzhj 2406 25 numeuos numeuos NN cord-005646-xhx9pzhj 2406 26 further further JJ cord-005646-xhx9pzhj 2406 27 complications complication NNS cord-005646-xhx9pzhj 2406 28 Bronchopulmonary Bronchopulmonary NNP cord-005646-xhx9pzhj 2406 29 dysptasia dysptasia NN cord-005646-xhx9pzhj 2406 30 ( ( -LRB- cord-005646-xhx9pzhj 2406 31 BDP BDP NNP cord-005646-xhx9pzhj 2406 32 ) ) -RRB- cord-005646-xhx9pzhj 2406 33 is be VBZ cord-005646-xhx9pzhj 2406 34 a a DT cord-005646-xhx9pzhj 2406 35 chronic chronic JJ cord-005646-xhx9pzhj 2406 36 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2406 37 disease disease NN cord-005646-xhx9pzhj 2406 38 of of IN cord-005646-xhx9pzhj 2406 39 preterm preterm NNS cord-005646-xhx9pzhj 2406 40 and and CC cord-005646-xhx9pzhj 2406 41 term term NN cord-005646-xhx9pzhj 2406 42 babies baby NNS cord-005646-xhx9pzhj 2406 43 treated treat VBN cord-005646-xhx9pzhj 2406 44 with with IN cord-005646-xhx9pzhj 2406 45 mechanical mechanical JJ cord-005646-xhx9pzhj 2406 46 ventilation ventilation NN cord-005646-xhx9pzhj 2406 47 for for IN cord-005646-xhx9pzhj 2406 48 respiratory respiratory JJ cord-005646-xhx9pzhj 2406 49 problems problem NNS cord-005646-xhx9pzhj 2406 50 of of IN cord-005646-xhx9pzhj 2406 51 different different JJ cord-005646-xhx9pzhj 2406 52 origin origin NN cord-005646-xhx9pzhj 2406 53 and and CC cord-005646-xhx9pzhj 2406 54 requiring require VBG cord-005646-xhx9pzhj 2406 55 oxygen oxygen NN cord-005646-xhx9pzhj 2406 56 therapy therapy NN cord-005646-xhx9pzhj 2406 57 28 28 CD cord-005646-xhx9pzhj 2406 58 days day NNS cord-005646-xhx9pzhj 2406 59 after after IN cord-005646-xhx9pzhj 2406 60 birth birth NN cord-005646-xhx9pzhj 2406 61 . . . cord-005646-xhx9pzhj 2407 1 BPD BPD NNP cord-005646-xhx9pzhj 2407 2 is be VBZ cord-005646-xhx9pzhj 2407 3 a a DT cord-005646-xhx9pzhj 2407 4 disease disease NN cord-005646-xhx9pzhj 2407 5 affecting affect VBG cord-005646-xhx9pzhj 2407 6 the the DT cord-005646-xhx9pzhj 2407 7 growth growth NN cord-005646-xhx9pzhj 2407 8 and and CC cord-005646-xhx9pzhj 2407 9 development development NN cord-005646-xhx9pzhj 2407 10 of of IN cord-005646-xhx9pzhj 2407 11 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2407 12 tissue tissue NN cord-005646-xhx9pzhj 2407 13 . . . cord-005646-xhx9pzhj 2408 1 Such such JJ cord-005646-xhx9pzhj 2408 2 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2408 3 } } -RRB- cord-005646-xhx9pzhj 2408 4 esions esion NNS cord-005646-xhx9pzhj 2408 5 heal heal VBP cord-005646-xhx9pzhj 2408 6 by by IN cord-005646-xhx9pzhj 2408 7 squamous squamous JJ cord-005646-xhx9pzhj 2408 8 metaplasia metaplasia NN cord-005646-xhx9pzhj 2408 9 leading lead VBG cord-005646-xhx9pzhj 2408 10 to to IN cord-005646-xhx9pzhj 2408 11 scar scar NN cord-005646-xhx9pzhj 2408 12 formation formation NN cord-005646-xhx9pzhj 2408 13 and and CC cord-005646-xhx9pzhj 2408 14 fibrous fibrous JJ cord-005646-xhx9pzhj 2408 15 tkssue tkssue NNP cord-005646-xhx9pzhj 2409 1 r r LS cord-005646-xhx9pzhj 2410 1 ~growth ~growth NNP cord-005646-xhx9pzhj 2411 1 , , , cord-005646-xhx9pzhj 2411 2 The the DT cord-005646-xhx9pzhj 2411 3 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2411 4 Intensive Intensive NNP cord-005646-xhx9pzhj 2411 5 Care Care NNP cord-005646-xhx9pzhj 2411 6 Unit Unit NNP cord-005646-xhx9pzhj 2411 7 makes make VBZ cord-005646-xhx9pzhj 2411 8 the the DT cord-005646-xhx9pzhj 2411 9 survival survival NN cord-005646-xhx9pzhj 2411 10 of of IN cord-005646-xhx9pzhj 2411 11 babies baby NNS cord-005646-xhx9pzhj 2412 1 w w NNP cord-005646-xhx9pzhj 2412 2 ~ ~ NFP cord-005646-xhx9pzhj 2412 3 h h NNP cord-005646-xhx9pzhj 2412 4 very very RB cord-005646-xhx9pzhj 2412 5 low low JJ cord-005646-xhx9pzhj 2412 6 birth birth NN cord-005646-xhx9pzhj 2412 7 weight weight NN cord-005646-xhx9pzhj 2412 8 ( ( -LRB- cord-005646-xhx9pzhj 2412 9 500 500 CD cord-005646-xhx9pzhj 2412 10 -999 -999 NN cord-005646-xhx9pzhj 2412 11 g g NN cord-005646-xhx9pzhj 2412 12 ) ) -RRB- cord-005646-xhx9pzhj 2412 13 possible possible JJ cord-005646-xhx9pzhj 2412 14 . . . cord-005646-xhx9pzhj 2413 1 With with IN cord-005646-xhx9pzhj 2413 2 the the DT cord-005646-xhx9pzhj 2413 3 increase increase NN cord-005646-xhx9pzhj 2413 4 in in IN cord-005646-xhx9pzhj 2413 5 their -PRON- PRP$ cord-005646-xhx9pzhj 2413 6 aulyival aulyival NN cord-005646-xhx9pzhj 2413 7 , , , cord-005646-xhx9pzhj 2413 8 the the DT cord-005646-xhx9pzhj 2413 9 number number NN cord-005646-xhx9pzhj 2413 10 of of IN cord-005646-xhx9pzhj 2413 11 complications complication NNS cord-005646-xhx9pzhj 2413 12 in in IN cord-005646-xhx9pzhj 2413 13 low low JJ cord-005646-xhx9pzhj 2413 14 birth birth NN cord-005646-xhx9pzhj 2413 15 weight weight NN cord-005646-xhx9pzhj 2413 16 babies baby NNS cord-005646-xhx9pzhj 2413 17 increases increase VBZ cord-005646-xhx9pzhj 2413 18 as as RB cord-005646-xhx9pzhj 2413 19 well well RB cord-005646-xhx9pzhj 2413 20 . . . cord-005646-xhx9pzhj 2414 1 BDP BDP NNP cord-005646-xhx9pzhj 2414 2 is be VBZ cord-005646-xhx9pzhj 2414 3 a a DT cord-005646-xhx9pzhj 2414 4 very very RB cord-005646-xhx9pzhj 2414 5 serious serious JJ cord-005646-xhx9pzhj 2414 6 complication complication NN cord-005646-xhx9pzhj 2414 7 . . . cord-005646-xhx9pzhj 2415 1 Therefore therefore RB cord-005646-xhx9pzhj 2415 2 the the DT cord-005646-xhx9pzhj 2415 3 importance importance NN cord-005646-xhx9pzhj 2415 4 of of IN cord-005646-xhx9pzhj 2415 5 early early JJ cord-005646-xhx9pzhj 2415 6 diagnosis diagnosis NN cord-005646-xhx9pzhj 2415 7 and and CC cord-005646-xhx9pzhj 2415 8 treatment treatment NN cord-005646-xhx9pzhj 2415 9 of of IN cord-005646-xhx9pzhj 2415 10 BDP BDP NNP cord-005646-xhx9pzhj 2415 11 must must MD cord-005646-xhx9pzhj 2415 12 be be VB cord-005646-xhx9pzhj 2415 13 stressed stress VBN cord-005646-xhx9pzhj 2415 14 in in IN cord-005646-xhx9pzhj 2415 15 order order NN cord-005646-xhx9pzhj 2415 16 to to TO cord-005646-xhx9pzhj 2415 17 reduce reduce VB cord-005646-xhx9pzhj 2415 18 the the DT cord-005646-xhx9pzhj 2415 19 consequences consequence NNS cord-005646-xhx9pzhj 2415 20 . . . cord-005646-xhx9pzhj 2416 1 Babies baby NNS cord-005646-xhx9pzhj 2416 2 with with IN cord-005646-xhx9pzhj 2416 3 BDP BDP NNP cord-005646-xhx9pzhj 2416 4 must must MD cord-005646-xhx9pzhj 2416 5 be be VB cord-005646-xhx9pzhj 2416 6 under under IN cord-005646-xhx9pzhj 2416 7 medical medical JJ cord-005646-xhx9pzhj 2416 8 suveillance suveillance NN cord-005646-xhx9pzhj 2416 9 for for IN cord-005646-xhx9pzhj 2416 10 at at RB cord-005646-xhx9pzhj 2416 11 least least JJS cord-005646-xhx9pzhj 2416 12 3 3 CD cord-005646-xhx9pzhj 2416 13 years year NNS cord-005646-xhx9pzhj 2416 14 as as IN cord-005646-xhx9pzhj 2416 15 the the DT cord-005646-xhx9pzhj 2416 16 disease disease NN cord-005646-xhx9pzhj 2416 17 needs need VBZ cord-005646-xhx9pzhj 2416 18 at at IN cord-005646-xhx9pzhj 2416 19 least least JJS cord-005646-xhx9pzhj 2416 20 that that RB cord-005646-xhx9pzhj 2416 21 long long RB cord-005646-xhx9pzhj 2416 22 for for IN cord-005646-xhx9pzhj 2416 23 complete complete JJ cord-005646-xhx9pzhj 2416 24 resolution resolution NN cord-005646-xhx9pzhj 2416 25 . . . cord-005646-xhx9pzhj 2417 1 tn tn NNP cord-005646-xhx9pzhj 2417 2 the the DT cord-005646-xhx9pzhj 2417 3 ICU ICU NNP cord-005646-xhx9pzhj 2417 4 of of IN cord-005646-xhx9pzhj 2417 5 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2417 6 Department Department NNP cord-005646-xhx9pzhj 2417 7 at at IN cord-005646-xhx9pzhj 2417 8 Madbor Madbor NNP cord-005646-xhx9pzhj 2417 9 Teaching Teaching NNP cord-005646-xhx9pzhj 2417 10 Hospital Hospital NNP cord-005646-xhx9pzhj 2417 11 : : : cord-005646-xhx9pzhj 2417 12 during during IN cord-005646-xhx9pzhj 2417 13 the the DT cord-005646-xhx9pzhj 2417 14 past past JJ cord-005646-xhx9pzhj 2417 15 two two CD cord-005646-xhx9pzhj 2417 16 years year NNS cord-005646-xhx9pzhj 2417 17 ( ( -LRB- cord-005646-xhx9pzhj 2417 18 1994 1994 CD cord-005646-xhx9pzhj 2417 19 - - SYM cord-005646-xhx9pzhj 2417 20 95 95 CD cord-005646-xhx9pzhj 2417 21 ) ) -RRB- cord-005646-xhx9pzhj 2417 22 154 154 CD cord-005646-xhx9pzhj 2417 23 newborns newborn NNS cord-005646-xhx9pzhj 2417 24 were be VBD cord-005646-xhx9pzhj 2417 25 treated treat VBN cord-005646-xhx9pzhj 2417 26 with with IN cord-005646-xhx9pzhj 2417 27 mechanical mechanical JJ cord-005646-xhx9pzhj 2417 28 ventilation ventilation NN cord-005646-xhx9pzhj 2417 29 . . . cord-005646-xhx9pzhj 2418 1 The the DT cord-005646-xhx9pzhj 2418 2 neonatal neonatal JJ cord-005646-xhx9pzhj 2418 3 and and CC cord-005646-xhx9pzhj 2418 4 postnatal postnatal JJ cord-005646-xhx9pzhj 2418 5 death death NN cord-005646-xhx9pzhj 2418 6 rate rate NN cord-005646-xhx9pzhj 2418 7 of of IN cord-005646-xhx9pzhj 2418 8 all all DT cord-005646-xhx9pzhj 2418 9 newborns newborn NNS cord-005646-xhx9pzhj 2418 10 admitted admit VBN cord-005646-xhx9pzhj 2418 11 to to IN cord-005646-xhx9pzhj 2418 12 our -PRON- PRP$ cord-005646-xhx9pzhj 2418 13 ICU ICU NNP cord-005646-xhx9pzhj 2418 14 was be VBD cord-005646-xhx9pzhj 2418 15 7,1%o.ln 7,1%o.ln CD cord-005646-xhx9pzhj 2419 1 the the DT cord-005646-xhx9pzhj 2419 2 two two CD cord-005646-xhx9pzhj 2419 3 years year NNS cord-005646-xhx9pzhj 2419 4 from from IN cord-005646-xhx9pzhj 2419 5 1994 1994 CD cord-005646-xhx9pzhj 2419 6 to to IN cord-005646-xhx9pzhj 2419 7 1995 1995 CD cord-005646-xhx9pzhj 2419 8 , , , cord-005646-xhx9pzhj 2419 9 16 16 CD cord-005646-xhx9pzhj 2419 10 newborns newborn NNS cord-005646-xhx9pzhj 2419 11 were be VBD cord-005646-xhx9pzhj 2419 12 admitted admit VBN cord-005646-xhx9pzhj 2419 13 to to IN cord-005646-xhx9pzhj 2419 14 our -PRON- PRP$ cord-005646-xhx9pzhj 2419 15 ICU ICU NNP cord-005646-xhx9pzhj 2419 16 ( ( -LRB- cord-005646-xhx9pzhj 2419 17 2 2 CD cord-005646-xhx9pzhj 2419 18 % % NN cord-005646-xhx9pzhj 2419 19 ~ ~ NFP cord-005646-xhx9pzhj 2419 20 of of IN cord-005646-xhx9pzhj 2419 21 all all DT cord-005646-xhx9pzhj 2419 22 newborn newborn JJ cord-005646-xhx9pzhj 2419 23 babies baby NNS cord-005646-xhx9pzhj 2419 24 at at IN cord-005646-xhx9pzhj 2419 25 Maribor Maribor NNP cord-005646-xhx9pzhj 2419 26 Teaching Teaching NNP cord-005646-xhx9pzhj 2419 27 Hospital Hospital NNP cord-005646-xhx9pzhj 2419 28 ) ) -RRB- cord-005646-xhx9pzhj 2419 29 , , , cord-005646-xhx9pzhj 2419 30 with with IN cord-005646-xhx9pzhj 2419 31 birth birth NN cord-005646-xhx9pzhj 2419 32 weight weight NN cord-005646-xhx9pzhj 2419 33 500 500 CD cord-005646-xhx9pzhj 2419 34 - - SYM cord-005646-xhx9pzhj 2419 35 999 999 CD cord-005646-xhx9pzhj 2419 36 g. g. NN cord-005646-xhx9pzhj 2420 1 In in IN cord-005646-xhx9pzhj 2420 2 the the DT cord-005646-xhx9pzhj 2420 3 ICU ICU NNP cord-005646-xhx9pzhj 2420 4 , , , cord-005646-xhx9pzhj 2420 5 the the DT cord-005646-xhx9pzhj 2420 6 survival survival NN cord-005646-xhx9pzhj 2420 7 of of IN cord-005646-xhx9pzhj 2420 8 these these DT cord-005646-xhx9pzhj 2420 9 babies baby NNS cord-005646-xhx9pzhj 2420 10 and and CC cord-005646-xhx9pzhj 2420 11 parallel parallel JJ cord-005646-xhx9pzhj 2420 12 to to IN cord-005646-xhx9pzhj 2420 13 it -PRON- PRP cord-005646-xhx9pzhj 2420 14 the the DT cord-005646-xhx9pzhj 2420 15 number number NN cord-005646-xhx9pzhj 2420 16 of of IN cord-005646-xhx9pzhj 2420 17 complications complication NNS cord-005646-xhx9pzhj 2420 18 is be VBZ cord-005646-xhx9pzhj 2420 19 increasing increase VBG cord-005646-xhx9pzhj 2420 20 . . . cord-005646-xhx9pzhj 2421 1 During during IN cord-005646-xhx9pzhj 2421 2 the the DT cord-005646-xhx9pzhj 2421 3 mentioned mention VBN cord-005646-xhx9pzhj 2421 4 2-year 2-year CD cord-005646-xhx9pzhj 2421 5 period period NN cord-005646-xhx9pzhj 2421 6 , , , cord-005646-xhx9pzhj 2421 7 8 8 CD cord-005646-xhx9pzhj 2421 8 babies baby NNS cord-005646-xhx9pzhj 2421 9 with with IN cord-005646-xhx9pzhj 2421 10 very very RB cord-005646-xhx9pzhj 2421 11 low low JJ cord-005646-xhx9pzhj 2421 12 birth birth NN cord-005646-xhx9pzhj 2421 13 weight weight NN cord-005646-xhx9pzhj 2421 14 ( ( -LRB- cord-005646-xhx9pzhj 2421 15 500 500 CD cord-005646-xhx9pzhj 2421 16 - - SYM cord-005646-xhx9pzhj 2421 17 999 999 CD cord-005646-xhx9pzhj 2421 18 g g NN cord-005646-xhx9pzhj 2421 19 ) ) -RRB- cord-005646-xhx9pzhj 2421 20 survived survive VBD cord-005646-xhx9pzhj 2421 21 : : : cord-005646-xhx9pzhj 2421 22 5 5 CD cord-005646-xhx9pzhj 2421 23 in in IN cord-005646-xhx9pzhj 2421 24 1994 1994 CD cord-005646-xhx9pzhj 2421 25 and and CC cord-005646-xhx9pzhj 2421 26 3 3 CD cord-005646-xhx9pzhj 2421 27 in in IN cord-005646-xhx9pzhj 2421 28 t995 t995 NNP cord-005646-xhx9pzhj 2421 29 . . . cord-005646-xhx9pzhj 2422 1 In in IN cord-005646-xhx9pzhj 2422 2 45 45 CD cord-005646-xhx9pzhj 2422 3 - - SYM cord-005646-xhx9pzhj 2422 4 50 50 CD cord-005646-xhx9pzhj 2422 5 % % NN cord-005646-xhx9pzhj 2422 6 , , , cord-005646-xhx9pzhj 2422 7 first first JJ cord-005646-xhx9pzhj 2422 8 or or CC cord-005646-xhx9pzhj 2422 9 second second JJ cord-005646-xhx9pzhj 2422 10 stage stage NN cord-005646-xhx9pzhj 2422 11 BDP BDP NNP cord-005646-xhx9pzhj 2422 12 was be VBD cord-005646-xhx9pzhj 2422 13 treated treat VBN cord-005646-xhx9pzhj 2422 14 , , , cord-005646-xhx9pzhj 2422 15 there there EX cord-005646-xhx9pzhj 2422 16 was be VBD cord-005646-xhx9pzhj 2422 17 no no DT cord-005646-xhx9pzhj 2422 18 case case NN cord-005646-xhx9pzhj 2422 19 of of IN cord-005646-xhx9pzhj 2422 20 third third JJ cord-005646-xhx9pzhj 2422 21 of of IN cord-005646-xhx9pzhj 2422 22 fourth fourth JJ cord-005646-xhx9pzhj 2422 23 stage stage NN cord-005646-xhx9pzhj 2422 24 BDP BDP NNP cord-005646-xhx9pzhj 2422 25 . . . cord-005646-xhx9pzhj 2423 1 The the DT cord-005646-xhx9pzhj 2423 2 treatment treatment NN cord-005646-xhx9pzhj 2423 3 consisted consist VBD cord-005646-xhx9pzhj 2423 4 of of IN cord-005646-xhx9pzhj 2423 5 eary eary JJ cord-005646-xhx9pzhj 2423 6 removal removal NN cord-005646-xhx9pzhj 2423 7 from from IN cord-005646-xhx9pzhj 2423 8 mechanical mechanical JJ cord-005646-xhx9pzhj 2423 9 ventilation ventilation NN cord-005646-xhx9pzhj 2423 10 , , , cord-005646-xhx9pzhj 2423 11 oxygen oxygen NN cord-005646-xhx9pzhj 2423 12 therapy~ therapy~ NNP cord-005646-xhx9pzhj 2423 13 intensive intensive JJ cord-005646-xhx9pzhj 2423 14 treatment treatment NN cord-005646-xhx9pzhj 2423 15 of of IN cord-005646-xhx9pzhj 2423 16 infection infection NN cord-005646-xhx9pzhj 2423 17 , , , cord-005646-xhx9pzhj 2423 18 volume volume NN cord-005646-xhx9pzhj 2423 19 and and CC cord-005646-xhx9pzhj 2423 20 caloric caloric JJ cord-005646-xhx9pzhj 2423 21 intake intake NN cord-005646-xhx9pzhj 2423 22 contro contro NNP cord-005646-xhx9pzhj 2423 23 } } -RRB- cord-005646-xhx9pzhj 2423 24 , , , cord-005646-xhx9pzhj 2423 25 corticosteroid corticosteroid NN cord-005646-xhx9pzhj 2423 26 treatment treatment NN cord-005646-xhx9pzhj 2423 27 throught throught IN cord-005646-xhx9pzhj 2423 28 6 6 CD cord-005646-xhx9pzhj 2423 29 weeks week NNS cord-005646-xhx9pzhj 2423 30 with with IN cord-005646-xhx9pzhj 2423 31 decreasing decrease VBG cord-005646-xhx9pzhj 2423 32 doses dose NNS cord-005646-xhx9pzhj 2423 33 , , , cord-005646-xhx9pzhj 2423 34 diuretic diuretic JJ cord-005646-xhx9pzhj 2423 35 end end NN cord-005646-xhx9pzhj 2423 36 antioxydant antioxydant JJ cord-005646-xhx9pzhj 2423 37 therapy therapy NN cord-005646-xhx9pzhj 2423 38 . . . cord-005646-xhx9pzhj 2424 1 The the DT cord-005646-xhx9pzhj 2424 2 children child NNS cord-005646-xhx9pzhj 2424 3 are be VBP cord-005646-xhx9pzhj 2424 4 to to TO cord-005646-xhx9pzhj 2424 5 be be VB cord-005646-xhx9pzhj 2424 6 reevaluated reevaluate VBN cord-005646-xhx9pzhj 2424 7 at at IN cord-005646-xhx9pzhj 2424 8 the the DT cord-005646-xhx9pzhj 2424 9 age age NN cord-005646-xhx9pzhj 2424 10 of of IN cord-005646-xhx9pzhj 2424 11 3 3 CD cord-005646-xhx9pzhj 2424 12 and and CC cord-005646-xhx9pzhj 2424 13 6 6 CD cord-005646-xhx9pzhj 2424 14 months month NNS cord-005646-xhx9pzhj 2424 15 and and CC cord-005646-xhx9pzhj 2424 16 again again RB cord-005646-xhx9pzhj 2424 17 at at IN cord-005646-xhx9pzhj 2424 18 I -PRON- PRP cord-005646-xhx9pzhj 2424 19 and and CC cord-005646-xhx9pzhj 2424 20 3 3 CD cord-005646-xhx9pzhj 2424 21 years year NNS cord-005646-xhx9pzhj 2424 22 . . . cord-005646-xhx9pzhj 2425 1 oeure oeure NNP cord-005646-xhx9pzhj 2425 2 J J NNP cord-005646-xhx9pzhj 2425 3 van van NNP cord-005646-xhx9pzhj 2425 4 der der NNP cord-005646-xhx9pzhj 2425 5 , , , cord-005646-xhx9pzhj 2425 6 Markhorst Markhorst NNP cord-005646-xhx9pzhj 2425 7 DO DO NNP cord-005646-xhx9pzhj 2425 8 , , , cord-005646-xhx9pzhj 2425 9 Haasnoot Haasnoot NNP cord-005646-xhx9pzhj 2425 10 K K NNP cord-005646-xhx9pzhj 2425 11 Department Department NNP cord-005646-xhx9pzhj 2425 12 Of of IN cord-005646-xhx9pzhj 2425 13 pediatrics pediatric NNS cord-005646-xhx9pzhj 2425 14 , , , cord-005646-xhx9pzhj 2425 15 pediatric pediatric JJ cord-005646-xhx9pzhj 2425 16 intensive intensive JJ cord-005646-xhx9pzhj 2425 17 care care NN cord-005646-xhx9pzhj 2425 18 unit unit NN cord-005646-xhx9pzhj 2425 19 , , , cord-005646-xhx9pzhj 2425 20 Free Free NNP cord-005646-xhx9pzhj 2425 21 University University NNP cord-005646-xhx9pzhj 2425 22 Hospital Hospital NNP cord-005646-xhx9pzhj 2425 23 , , , cord-005646-xhx9pzhj 2425 24 Amsterdam Amsterdam NNP cord-005646-xhx9pzhj 2425 25 , , , cord-005646-xhx9pzhj 2425 26 the the DT cord-005646-xhx9pzhj 2425 27 Netherlands Netherlands NNP cord-005646-xhx9pzhj 2425 28 . . . cord-005646-xhx9pzhj 2426 1 Case Case NNP cord-005646-xhx9pzhj 2426 2 Summary Summary NNP cord-005646-xhx9pzhj 2426 3 A A NNP cord-005646-xhx9pzhj 2426 4 4%-month 4%-month CD cord-005646-xhx9pzhj 2426 5 6.5 6.5 CD cord-005646-xhx9pzhj 2426 6 Kg Kg NNP cord-005646-xhx9pzhj 2426 7 girl girl NN cord-005646-xhx9pzhj 2426 8 of of IN cord-005646-xhx9pzhj 2426 9 African african JJ cord-005646-xhx9pzhj 2426 10 origin origin NN cord-005646-xhx9pzhj 2426 11 was be VBD cord-005646-xhx9pzhj 2426 12 admitted admit VBN cord-005646-xhx9pzhj 2426 13 to to IN cord-005646-xhx9pzhj 2426 14 the the DT cord-005646-xhx9pzhj 2426 15 Pedfatric Pedfatric NNP cord-005646-xhx9pzhj 2426 16 IRtensive IRtensive NNP cord-005646-xhx9pzhj 2426 17 Care Care NNP cord-005646-xhx9pzhj 2426 18 Unit Unit NNP cord-005646-xhx9pzhj 2426 19 with with IN cord-005646-xhx9pzhj 2426 20 pneumonia pneumonia NN cord-005646-xhx9pzhj 2426 21 and and CC cord-005646-xhx9pzhj 2426 22 progressive progressive JJ cord-005646-xhx9pzhj 2426 23 respiratory respiratory JJ cord-005646-xhx9pzhj 2426 24 irlsuffJdeRey irlsuffjderey NN cord-005646-xhx9pzhj 2426 25 . . . cord-005646-xhx9pzhj 2427 1 She -PRON- PRP cord-005646-xhx9pzhj 2427 2 was be VBD cord-005646-xhx9pzhj 2427 3 intubated intubate VBN cord-005646-xhx9pzhj 2427 4 and and CC cord-005646-xhx9pzhj 2427 5 ventilated ventilate VBN cord-005646-xhx9pzhj 2427 6 by by IN cord-005646-xhx9pzhj 2427 7 pressure pressure NN cord-005646-xhx9pzhj 2427 8 regulated regulate VBN cord-005646-xhx9pzhj 2427 9 volume volume NN cord-005646-xhx9pzhj 2427 10 controiJed controiJed NNP cord-005646-xhx9pzhj 2427 11 ventilation ventilation NN cord-005646-xhx9pzhj 2427 12 ( ( -LRB- cord-005646-xhx9pzhj 2427 13 Servo Servo NNP cord-005646-xhx9pzhj 2427 14 300C 300C NNP cord-005646-xhx9pzhj 2427 15 , , , cord-005646-xhx9pzhj 2427 16 siemens siemens NNP cord-005646-xhx9pzhj 2427 17 , , , cord-005646-xhx9pzhj 2427 18 Soma Soma NNP cord-005646-xhx9pzhj 2427 19 , , , cord-005646-xhx9pzhj 2427 20 Sweden Sweden NNP cord-005646-xhx9pzhj 2427 21 ) ) -RRB- cord-005646-xhx9pzhj 2427 22 . . . cord-005646-xhx9pzhj 2428 1 Maximum maximum JJ cord-005646-xhx9pzhj 2428 2 conditions condition NNS cord-005646-xhx9pzhj 2428 3 were be VBD cord-005646-xhx9pzhj 2428 4 InspiratorY inspiratory RB cord-005646-xhx9pzhj 2428 5 Minute Minute NNP cord-005646-xhx9pzhj 2428 6 volume volume NN cord-005646-xhx9pzhj 2428 7 3.2 3.2 CD cord-005646-xhx9pzhj 2428 8 l l NN cord-005646-xhx9pzhj 2428 9 , , , cord-005646-xhx9pzhj 2428 10 PEEP PEEP NNP cord-005646-xhx9pzhj 2428 11 10 10 CD cord-005646-xhx9pzhj 2428 12 cm cm NN cord-005646-xhx9pzhj 2428 13 H~ H~ NNS cord-005646-xhx9pzhj 2429 1 O o UH cord-005646-xhx9pzhj 2429 2 ahd ahd NNP cord-005646-xhx9pzhj 2429 3 100 100 CD cord-005646-xhx9pzhj 2429 4 % % NN cord-005646-xhx9pzhj 2429 5 0~. 0~. CD cord-005646-xhx9pzhj 2430 1 Chest chest NN cord-005646-xhx9pzhj 2430 2 X x NN cord-005646-xhx9pzhj 2430 3 - - NN cord-005646-xhx9pzhj 2430 4 ray ray NN cord-005646-xhx9pzhj 2430 5 ShOwed showed VBP cord-005646-xhx9pzhj 2430 6 bilateral bilateral JJ cord-005646-xhx9pzhj 2430 7 interstitial interstitial JJ cord-005646-xhx9pzhj 2430 8 consolidation consolidation NN cord-005646-xhx9pzhj 2430 9 . . . cord-005646-xhx9pzhj 2431 1 Material material NN cord-005646-xhx9pzhj 2431 2 obtained obtain VBN cord-005646-xhx9pzhj 2431 3 by by IN cord-005646-xhx9pzhj 2431 4 broncho broncho JJ cord-005646-xhx9pzhj 2431 5 - - HYPH cord-005646-xhx9pzhj 2431 6 alveolar alveolar NN cord-005646-xhx9pzhj 2431 7 lavage lavage NN cord-005646-xhx9pzhj 2431 8 showed show VBD cord-005646-xhx9pzhj 2431 9 PReumocystis preumocystis JJ cord-005646-xhx9pzhj 2431 10 Car}niL car}nil NN cord-005646-xhx9pzhj 2431 11 Htv Htv NNP cord-005646-xhx9pzhj 2431 12 - - HYPH cord-005646-xhx9pzhj 2431 13 serology serology NN cord-005646-xhx9pzhj 2431 14 ( ( -LRB- cord-005646-xhx9pzhj 2431 15 Elisa Elisa NNP cord-005646-xhx9pzhj 2431 16 and and CC cord-005646-xhx9pzhj 2431 17 Westerll Westerll NNP cord-005646-xhx9pzhj 2431 18 blott blott NNP cord-005646-xhx9pzhj 2431 19 ) ) -RRB- cord-005646-xhx9pzhj 2431 20 and and CC cord-005646-xhx9pzhj 2431 21 p24-antigerl p24-antigerl NNP cord-005646-xhx9pzhj 2431 22 were be VBD cord-005646-xhx9pzhj 2431 23 positive positive JJ cord-005646-xhx9pzhj 2431 24 , , , cord-005646-xhx9pzhj 2431 25 confirming confirm VBG cord-005646-xhx9pzhj 2431 26 the the DT cord-005646-xhx9pzhj 2431 27 diagnosis diagnosis NN cord-005646-xhx9pzhj 2431 28 Of of IN cord-005646-xhx9pzhj 2431 29 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2431 30 AIDS AIDS NNP cord-005646-xhx9pzhj 2431 31 . . . cord-005646-xhx9pzhj 2432 1 She -PRON- PRP cord-005646-xhx9pzhj 2432 2 was be VBD cord-005646-xhx9pzhj 2432 3 then then RB cord-005646-xhx9pzhj 2432 4 treated treat VBN cord-005646-xhx9pzhj 2432 5 with with IN cord-005646-xhx9pzhj 2432 6 high high JJ cord-005646-xhx9pzhj 2432 7 dose dose NN cord-005646-xhx9pzhj 2432 8 Co co NN cord-005646-xhx9pzhj 2432 9 - - NN cord-005646-xhx9pzhj 2432 10 tllmoxazoie tllmoxazoie NNP cord-005646-xhx9pzhj 2432 11 , , , cord-005646-xhx9pzhj 2432 12 Penthamldine Penthamldine NNP cord-005646-xhx9pzhj 2432 13 , , , cord-005646-xhx9pzhj 2432 14 Z{(~ovudiRe Z{(~ovudiRe NNS cord-005646-xhx9pzhj 2432 15 and and CC cord-005646-xhx9pzhj 2432 16 steroids steroid NNS cord-005646-xhx9pzhj 2432 17 iv iv NNP cord-005646-xhx9pzhj 2432 18 . . . cord-005646-xhx9pzhj 2433 1 Because because IN cord-005646-xhx9pzhj 2433 2 of of IN cord-005646-xhx9pzhj 2433 3 thee thee NN cord-005646-xhx9pzhj 2433 4 x x NN cord-005646-xhx9pzhj 2433 5 - - NN cord-005646-xhx9pzhj 2433 6 ray ray NN cord-005646-xhx9pzhj 2433 7 features feature NNS cord-005646-xhx9pzhj 2433 8 , , , cord-005646-xhx9pzhj 2433 9 high high JJ cord-005646-xhx9pzhj 2433 10 need need NN cord-005646-xhx9pzhj 2433 11 for for IN cord-005646-xhx9pzhj 2433 12 O o NN cord-005646-xhx9pzhj 2433 13 2 2 CD cord-005646-xhx9pzhj 2433 14 ( ( -LRB- cord-005646-xhx9pzhj 2433 15 100 100 CD cord-005646-xhx9pzhj 2433 16 % % NN cord-005646-xhx9pzhj 2433 17 , , , cord-005646-xhx9pzhj 2433 18 pad pad NN cord-005646-xhx9pzhj 2433 19 2 2 CD cord-005646-xhx9pzhj 2433 20 56 56 CD cord-005646-xhx9pzhj 2433 21 mm mm CD cord-005646-xhx9pzhj 2433 22 Hg Hg NNP cord-005646-xhx9pzhj 2433 23 ) ) -RRB- cord-005646-xhx9pzhj 2433 24 , , , cord-005646-xhx9pzhj 2433 25 not not RB cord-005646-xhx9pzhj 2433 26 responding respond VBG cord-005646-xhx9pzhj 2433 27 to to IN cord-005646-xhx9pzhj 2433 28 elevatiofi elevatiofi NN cord-005646-xhx9pzhj 2433 29 of of IN cord-005646-xhx9pzhj 2433 30 PEEP peep NN cord-005646-xhx9pzhj 2434 1 ( ( -LRB- cord-005646-xhx9pzhj 2434 2 max max NNP cord-005646-xhx9pzhj 2435 1 10 10 CD cord-005646-xhx9pzhj 2435 2 cm cm NN cord-005646-xhx9pzhj 2435 3 H h NN cord-005646-xhx9pzhj 2435 4 = = SYM cord-005646-xhx9pzhj 2435 5 O o NN cord-005646-xhx9pzhj 2435 6 ) ) -RRB- cord-005646-xhx9pzhj 2436 1 and and CC cord-005646-xhx9pzhj 2436 2 PaO2 PaO2 NNS cord-005646-xhx9pzhj 2436 3 / / SYM cord-005646-xhx9pzhj 2436 4 FiO FiO NNS cord-005646-xhx9pzhj 2436 5 = = NFP cord-005646-xhx9pzhj 2437 1 < < XX cord-005646-xhx9pzhj 2437 2 200 200 CD cord-005646-xhx9pzhj 2437 3 ( ( -LRB- cord-005646-xhx9pzhj 2437 4 S6 S6 NNP cord-005646-xhx9pzhj 2437 5 ) ) -RRB- cord-005646-xhx9pzhj 2437 6 . . . cord-005646-xhx9pzhj 2438 1 m m LS cord-005646-xhx9pzhj 2438 2 Acute Acute NNP cord-005646-xhx9pzhj 2438 3 Respiratory respiratory JJ cord-005646-xhx9pzhj 2438 4 Distress distress NN cord-005646-xhx9pzhj 2438 5 Syhdrome Syhdrome NNP cord-005646-xhx9pzhj 2438 6 ( ( -LRB- cord-005646-xhx9pzhj 2438 7 ARDS ARDS NNP cord-005646-xhx9pzhj 2438 8 ) ) -RRB- cord-005646-xhx9pzhj 2438 9 was be VBD cord-005646-xhx9pzhj 2438 10 diagnosed diagnose VBN cord-005646-xhx9pzhj 2438 11 . . . cord-005646-xhx9pzhj 2439 1 Because because IN cord-005646-xhx9pzhj 2439 2 conventional conventional JJ cord-005646-xhx9pzhj 2439 3 ventilation ventilation NN cord-005646-xhx9pzhj 2439 4 ( ( -LRB- cord-005646-xhx9pzhj 2439 5 cv cv NN cord-005646-xhx9pzhj 2439 6 ) ) -RRB- cord-005646-xhx9pzhj 2439 7 failure failure NN cord-005646-xhx9pzhj 2439 8 , , , cord-005646-xhx9pzhj 2439 9 HFO HFO NNP cord-005646-xhx9pzhj 2439 10 - - HYPH cord-005646-xhx9pzhj 2439 11 V V NNP cord-005646-xhx9pzhj 2439 12 ( ( -LRB- cord-005646-xhx9pzhj 2439 13 31OOA 31OOA NNS cord-005646-xhx9pzhj 2439 14 , , , cord-005646-xhx9pzhj 2439 15 Serisor Serisor NNP cord-005646-xhx9pzhj 2439 16 Medics Medics NNPS cord-005646-xhx9pzhj 2439 17 , , , cord-005646-xhx9pzhj 2439 18 Yorba Yorba NNP cord-005646-xhx9pzhj 2439 19 Linda Linda NNP cord-005646-xhx9pzhj 2439 20 , , , cord-005646-xhx9pzhj 2439 21 Ca Ca NNP cord-005646-xhx9pzhj 2439 22 ) ) -RRB- cord-005646-xhx9pzhj 2439 23 was be VBD cord-005646-xhx9pzhj 2439 24 initiated initiate VBN cord-005646-xhx9pzhj 2439 25 . . . cord-005646-xhx9pzhj 2440 1 Starting start VBG cord-005646-xhx9pzhj 2440 2 Mean mean JJ cord-005646-xhx9pzhj 2440 3 Airway Airway NNP cord-005646-xhx9pzhj 2440 4 Pressure Pressure NNP cord-005646-xhx9pzhj 2440 5 ( ( -LRB- cord-005646-xhx9pzhj 2440 6 MAP MAP NNP cord-005646-xhx9pzhj 2440 7 ) ) -RRB- cord-005646-xhx9pzhj 2440 8 of of IN cord-005646-xhx9pzhj 2440 9 19 19 CD cord-005646-xhx9pzhj 2440 10 cm cm NNS cord-005646-xhx9pzhj 2440 11 H h NN cord-005646-xhx9pzhj 2441 1 ~O ~O NNP cord-005646-xhx9pzhj 2441 2 was be VBD cord-005646-xhx9pzhj 2441 3 based base VBN cord-005646-xhx9pzhj 2441 4 OR or CC cord-005646-xhx9pzhj 2441 5 MAP MAP NNP cord-005646-xhx9pzhj 2441 6 of of IN cord-005646-xhx9pzhj 2441 7 the the DT cord-005646-xhx9pzhj 2441 8 CV cv NN cord-005646-xhx9pzhj 2442 1 , , , cord-005646-xhx9pzhj 2442 2 Oscillatory oscillatory JJ cord-005646-xhx9pzhj 2442 3 pressure pressure NN cord-005646-xhx9pzhj 2442 4 amplitude amplitude NN cord-005646-xhx9pzhj 2442 5 ( ( -LRB- cord-005646-xhx9pzhj 2442 6 dP dP NNP cord-005646-xhx9pzhj 2442 7 ) ) -RRB- cord-005646-xhx9pzhj 2443 1 Of of IN cord-005646-xhx9pzhj 2443 2 47 47 CD cord-005646-xhx9pzhj 2443 3 was be VBD cord-005646-xhx9pzhj 2443 4 , , , cord-005646-xhx9pzhj 2443 5 at at IN cord-005646-xhx9pzhj 2443 6 ii ii NNP cord-005646-xhx9pzhj 2443 7 ~ ~ CD cord-005646-xhx9pzhj 2443 8 itial itial JJ cord-005646-xhx9pzhj 2443 9 frequency frequency NN cord-005646-xhx9pzhj 2443 10 of of IN cord-005646-xhx9pzhj 2443 11 7.5 7.5 CD cord-005646-xhx9pzhj 2443 12 Hz Hz NNP cord-005646-xhx9pzhj 2443 13 , , , cord-005646-xhx9pzhj 2443 14 adjusted adjust VBD cord-005646-xhx9pzhj 2443 15 ur ur UH cord-005646-xhx9pzhj 2443 16 ~ ~ NFP cord-005646-xhx9pzhj 2443 17 til til CC cord-005646-xhx9pzhj 2443 18 chest chest NN cord-005646-xhx9pzhj 2443 19 wall wall NN cord-005646-xhx9pzhj 2443 20 vibrations vibration NNS cord-005646-xhx9pzhj 2443 21 were be VBD cord-005646-xhx9pzhj 2443 22 visible visible JJ cord-005646-xhx9pzhj 2443 23 , , , cord-005646-xhx9pzhj 2443 24 it -PRON- PRP cord-005646-xhx9pzhj 2443 25 was be VBD cord-005646-xhx9pzhj 2443 26 required require VBN cord-005646-xhx9pzhj 2443 27 to to TO cord-005646-xhx9pzhj 2443 28 raise raise VB cord-005646-xhx9pzhj 2443 29 MAP MAP NNP cord-005646-xhx9pzhj 2443 30 to to IN cord-005646-xhx9pzhj 2443 31 26 26 CD cord-005646-xhx9pzhj 2443 32 cm cm NN cord-005646-xhx9pzhj 2443 33 H20 H20 NNP cord-005646-xhx9pzhj 2443 34 and and CC cord-005646-xhx9pzhj 2443 35 dP dP NNP cord-005646-xhx9pzhj 2443 36 to to IN cord-005646-xhx9pzhj 2443 37 66 66 CD cord-005646-xhx9pzhj 2443 38 before before IN cord-005646-xhx9pzhj 2443 39 optimal optimal JJ cord-005646-xhx9pzhj 2443 40 lung lung NN cord-005646-xhx9pzhj 2443 41 volume volume NN cord-005646-xhx9pzhj 2443 42 and and CC cord-005646-xhx9pzhj 2443 43 ventilation ventilation NN cord-005646-xhx9pzhj 2443 44 were be VBD cord-005646-xhx9pzhj 2443 45 achieved achieve VBN cord-005646-xhx9pzhj 2443 46 and and CC cord-005646-xhx9pzhj 2443 47 need need VBP cord-005646-xhx9pzhj 2443 48 for for IN cord-005646-xhx9pzhj 2443 49 O o NN cord-005646-xhx9pzhj 2443 50 2 2 CD cord-005646-xhx9pzhj 2443 51 reduced reduce VBN cord-005646-xhx9pzhj 2443 52 within within IN cord-005646-xhx9pzhj 2443 53 hours hour NNS cord-005646-xhx9pzhj 2443 54 , , , cord-005646-xhx9pzhj 2443 55 This this DT cord-005646-xhx9pzhj 2443 56 was be VBD cord-005646-xhx9pzhj 2443 57 monitored monitor VBN cord-005646-xhx9pzhj 2443 58 by by IN cord-005646-xhx9pzhj 2443 59 frequent frequent JJ cord-005646-xhx9pzhj 2443 60 blood blood NN cord-005646-xhx9pzhj 2443 61 - - HYPH cord-005646-xhx9pzhj 2443 62 gas gas NN cord-005646-xhx9pzhj 2443 63 analysis analysis NN cord-005646-xhx9pzhj 2443 64 and and CC cord-005646-xhx9pzhj 2443 65 chest chest NN cord-005646-xhx9pzhj 2443 66 x x NNS cord-005646-xhx9pzhj 2443 67 - - NNS cord-005646-xhx9pzhj 2443 68 rays ray NNS cord-005646-xhx9pzhj 2443 69 . . . cord-005646-xhx9pzhj 2444 1 MAP MAP NNP cord-005646-xhx9pzhj 2444 2 and and CC cord-005646-xhx9pzhj 2444 3 dP dP NNP cord-005646-xhx9pzhj 2444 4 could could MD cord-005646-xhx9pzhj 2444 5 slowly slowly RB cord-005646-xhx9pzhj 2444 6 be be VB cord-005646-xhx9pzhj 2444 7 reduced reduce VBN cord-005646-xhx9pzhj 2444 8 , , , cord-005646-xhx9pzhj 2444 9 After after IN cord-005646-xhx9pzhj 2444 10 a a DT cord-005646-xhx9pzhj 2444 11 good good JJ cord-005646-xhx9pzhj 2444 12 response response NN cord-005646-xhx9pzhj 2444 13 the the DT cord-005646-xhx9pzhj 2444 14 first first JJ cord-005646-xhx9pzhj 2444 15 day day NN cord-005646-xhx9pzhj 2444 16 , , , cord-005646-xhx9pzhj 2444 17 gradually gradually RB cord-005646-xhx9pzhj 2444 18 02demand 02demand CD cord-005646-xhx9pzhj 2444 19 reduced reduce VBN cord-005646-xhx9pzhj 2444 20 and and CC cord-005646-xhx9pzhj 2444 21 the the DT cord-005646-xhx9pzhj 2444 22 patient patient NN cord-005646-xhx9pzhj 2444 23 could could MD cord-005646-xhx9pzhj 2444 24 be be VB cord-005646-xhx9pzhj 2444 25 weaned wean VBN cord-005646-xhx9pzhj 2444 26 from from IN cord-005646-xhx9pzhj 2444 27 the the DT cord-005646-xhx9pzhj 2444 28 ventilation ventilation NN cord-005646-xhx9pzhj 2444 29 . . . cord-005646-xhx9pzhj 2445 1 MAP MAP NNP cord-005646-xhx9pzhj 2445 2 , , , cord-005646-xhx9pzhj 2445 3 dP dP NNP cord-005646-xhx9pzhj 2445 4 , , , cord-005646-xhx9pzhj 2445 5 Fi02 Fi02 NNP cord-005646-xhx9pzhj 2445 6 and and CC cord-005646-xhx9pzhj 2445 7 Oxygenation Oxygenation NNP cord-005646-xhx9pzhj 2445 8 index index NN cord-005646-xhx9pzhj 2445 9 ( ( -LRB- cord-005646-xhx9pzhj 2445 10 MAP map NN cord-005646-xhx9pzhj 2445 11 X x NN cord-005646-xhx9pzhj 2445 12 Pa0~JFiO Pa0~JFiO NNS cord-005646-xhx9pzhj 2445 13 2 2 CD cord-005646-xhx9pzhj 2445 14 ) ) -RRB- cord-005646-xhx9pzhj 2445 15 are be VBP cord-005646-xhx9pzhj 2445 16 shown show VBN cord-005646-xhx9pzhj 2445 17 in in IN cord-005646-xhx9pzhj 2445 18 table table NN cord-005646-xhx9pzhj 2445 19 I. I. NNP cord-005646-xhx9pzhj 2445 20 Chest Chest NNP cord-005646-xhx9pzhj 2445 21 X x NN cord-005646-xhx9pzhj 2445 22 - - NN cord-005646-xhx9pzhj 2445 23 ray ray NN cord-005646-xhx9pzhj 2445 24 follow follow NN cord-005646-xhx9pzhj 2445 25 - - HYPH cord-005646-xhx9pzhj 2445 26 up up NN cord-005646-xhx9pzhj 2445 27 showed show VBD cord-005646-xhx9pzhj 2445 28 gradually gradually RB cord-005646-xhx9pzhj 2445 29 improving improve VBG cord-005646-xhx9pzhj 2445 30 lung lung NN cord-005646-xhx9pzhj 2445 31 features feature NNS cord-005646-xhx9pzhj 2445 32 , , , cord-005646-xhx9pzhj 2445 33 with with IN cord-005646-xhx9pzhj 2445 34 marked marked JJ cord-005646-xhx9pzhj 2445 35 improvement improvement NN cord-005646-xhx9pzhj 2445 36 of of IN cord-005646-xhx9pzhj 2445 37 aereation aereation NN cord-005646-xhx9pzhj 2445 38 . . . cord-005646-xhx9pzhj 2446 1 After after IN cord-005646-xhx9pzhj 2446 2 10 10 CD cord-005646-xhx9pzhj 2446 3 days day NNS cord-005646-xhx9pzhj 2446 4 HF0-V HF0-V NNP cord-005646-xhx9pzhj 2446 5 she -PRON- PRP cord-005646-xhx9pzhj 2446 6 could could MD cord-005646-xhx9pzhj 2446 7 be be VB cord-005646-xhx9pzhj 2446 8 succesfully succesfully RB cord-005646-xhx9pzhj 2446 9 detubated detubate VBN cord-005646-xhx9pzhj 2446 10 when when WRB cord-005646-xhx9pzhj 2446 11 a a DT cord-005646-xhx9pzhj 2446 12 MAP MAP NNP cord-005646-xhx9pzhj 2446 13 of of IN cord-005646-xhx9pzhj 2446 14 10 10 CD cord-005646-xhx9pzhj 2446 15 cm cm NNS cord-005646-xhx9pzhj 2446 16 H20 H20 NNP cord-005646-xhx9pzhj 2446 17 was be VBD cord-005646-xhx9pzhj 2446 18 acmeved acmeved JJ cord-005646-xhx9pzhj 2446 19 . . . cord-005646-xhx9pzhj 2447 1 Results result NNS cord-005646-xhx9pzhj 2447 2 : : : cord-005646-xhx9pzhj 2448 1 Sianificant sianificant JJ cord-005646-xhx9pzhj 2448 2 increase increase NN cord-005646-xhx9pzhj 2448 3 in in IN cord-005646-xhx9pzhj 2448 4 ventilato~ ventilato~ NN cord-005646-xhx9pzhj 2448 5 rate rate NN cord-005646-xhx9pzhj 2448 6 and and CC cord-005646-xhx9pzhj 2448 7 mean mean VB cord-005646-xhx9pzhj 2448 8 airway airway NN cord-005646-xhx9pzhj 2448 9 pressure pressure NN cord-005646-xhx9pzhj 2448 10 was be VBD cord-005646-xhx9pzhj 2448 11 noticed notice VBN cord-005646-xhx9pzhj 2448 12 after after IN cord-005646-xhx9pzhj 2448 13 the the DT cord-005646-xhx9pzhj 2448 14 change change NN cord-005646-xhx9pzhj 2448 15 to to IN cord-005646-xhx9pzhj 2448 16 SAVI SAVI NNP cord-005646-xhx9pzhj 2448 17 . . . cord-005646-xhx9pzhj 2449 1 No no DT cord-005646-xhx9pzhj 2449 2 differences difference NNS cord-005646-xhx9pzhj 2449 3 in in IN cord-005646-xhx9pzhj 2449 4 oxygenation oxygenation NN cord-005646-xhx9pzhj 2449 5 , , , cord-005646-xhx9pzhj 2449 6 CO co NN cord-005646-xhx9pzhj 2449 7 2 2 CD cord-005646-xhx9pzhj 2449 8 partial partial JJ cord-005646-xhx9pzhj 2449 9 pressure pressure NN cord-005646-xhx9pzhj 2449 10 and and CC cord-005646-xhx9pzhj 2449 11 systolic systolic JJ cord-005646-xhx9pzhj 2449 12 , , , cord-005646-xhx9pzhj 2449 13 diastolic diastolic JJ cord-005646-xhx9pzhj 2449 14 or or CC cord-005646-xhx9pzhj 2449 15 mean mean VB cord-005646-xhx9pzhj 2449 16 blood blood NN cord-005646-xhx9pzhj 2449 17 pressure pressure NN cord-005646-xhx9pzhj 2449 18 between between IN cord-005646-xhx9pzhj 2449 19 IMV IMV NNP cord-005646-xhx9pzhj 2449 20 and and CC cord-005646-xhx9pzhj 2449 21 SAVI SAVI NNP cord-005646-xhx9pzhj 2449 22 periods period NNS cord-005646-xhx9pzhj 2449 23 were be VBD cord-005646-xhx9pzhj 2449 24 noted note VBN cord-005646-xhx9pzhj 2449 25 . . . cord-005646-xhx9pzhj 2450 1 In in IN cord-005646-xhx9pzhj 2450 2 6 6 CD cord-005646-xhx9pzhj 2450 3 infants infant NNS cord-005646-xhx9pzhj 2450 4 however however RB cord-005646-xhx9pzhj 2450 5 an an DT cord-005646-xhx9pzhj 2450 6 improvement improvement NN cord-005646-xhx9pzhj 2450 7 in in IN cord-005646-xhx9pzhj 2450 8 PaO2 PaO2 NNS cord-005646-xhx9pzhj 2450 9 / / SYM cord-005646-xhx9pzhj 2450 10 P43.Ol/ p43.ol/ NN cord-005646-xhx9pzhj 2450 11 and and CC cord-005646-xhx9pzhj 2450 12 decrease decrease NN cord-005646-xhx9pzhj 2450 13 in in IN cord-005646-xhx9pzhj 2450 14 PaCO paco NN cord-005646-xhx9pzhj 2450 15 2 2 CD cord-005646-xhx9pzhj 2450 16 was be VBD cord-005646-xhx9pzhj 2450 17 observed observe VBN cord-005646-xhx9pzhj 2450 18 after after IN cord-005646-xhx9pzhj 2450 19 the the DT cord-005646-xhx9pzhj 2450 20 switch switch NN cord-005646-xhx9pzhj 2450 21 to to IN cord-005646-xhx9pzhj 2450 22 SAVI SAVI NNP cord-005646-xhx9pzhj 2450 23 . . . cord-005646-xhx9pzhj 2451 1 These these DT cord-005646-xhx9pzhj 2451 2 babies baby NNS cord-005646-xhx9pzhj 2451 3 had have VBD cord-005646-xhx9pzhj 2451 4 a a DT cord-005646-xhx9pzhj 2451 5 lower low JJR cord-005646-xhx9pzhj 2451 6 initial initial JJ cord-005646-xhx9pzhj 2451 7 a a DT cord-005646-xhx9pzhj 2451 8 / / SYM cord-005646-xhx9pzhj 2451 9 A a DT cord-005646-xhx9pzhj 2451 10 oxygen oxygen NN cord-005646-xhx9pzhj 2451 11 tension tension NN cord-005646-xhx9pzhj 2451 12 ratio ratio NN cord-005646-xhx9pzhj 2451 13 and and CC cord-005646-xhx9pzhj 2451 14 required require VBN cord-005646-xhx9pzhj 2451 15 higher high JJR cord-005646-xhx9pzhj 2451 16 initial initial JJ cord-005646-xhx9pzhj 2451 17 ventilator ventilator NN cord-005646-xhx9pzhj 2451 18 rate rate NN cord-005646-xhx9pzhj 2451 19 /p /p NNP cord-005646-xhx9pzhj 2451 20 < < XX cord-005646-xhx9pzhj 2451 21 O.05/ O.05/ VBD cord-005646-xhx9pzhj 2451 22 in in IN cord-005646-xhx9pzhj 2451 23 comparison comparison NN cord-005646-xhx9pzhj 2451 24 to to IN cord-005646-xhx9pzhj 2451 25 the the DT cord-005646-xhx9pzhj 2451 26 rest rest NN cord-005646-xhx9pzhj 2451 27 of of IN cord-005646-xhx9pzhj 2451 28 the the DT cord-005646-xhx9pzhj 2451 29 studied study VBN cord-005646-xhx9pzhj 2451 30 patients patient NNS cord-005646-xhx9pzhj 2451 31 . . . cord-005646-xhx9pzhj 2452 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2452 2 : : : cord-005646-xhx9pzhj 2452 3 Infants infant NNS cord-005646-xhx9pzhj 2452 4 with with IN cord-005646-xhx9pzhj 2452 5 low low JJ cord-005646-xhx9pzhj 2452 6 a/ a/ NNP cord-005646-xhx9pzhj 2453 1 A a DT cord-005646-xhx9pzhj 2453 2 PO2ratio PO2ratio NNP cord-005646-xhx9pzhj 2453 3 who who WP cord-005646-xhx9pzhj 2453 4 need need VBP cord-005646-xhx9pzhj 2453 5 high high JJ cord-005646-xhx9pzhj 2453 6 initial initial JJ cord-005646-xhx9pzhj 2453 7 ventilator ventilator NN cord-005646-xhx9pzhj 2453 8 rate rate NN cord-005646-xhx9pzhj 2453 9 are be VBP cord-005646-xhx9pzhj 2453 10 likely likely JJ cord-005646-xhx9pzhj 2453 11 to to TO cord-005646-xhx9pzhj 2453 12 obtain obtain VB cord-005646-xhx9pzhj 2453 13 benefit benefit NN cord-005646-xhx9pzhj 2453 14 from from IN cord-005646-xhx9pzhj 2453 15 SAVI SAVI NNP cord-005646-xhx9pzhj 2453 16 .. .. . cord-005646-xhx9pzhj 2454 1 Fumimare fumimare NN cord-005646-xhx9pzhj 2454 2 HATORI HATORI NNP cord-005646-xhx9pzhj 2454 3 , , , cord-005646-xhx9pzhj 2454 4 Haruo Haruo NNP cord-005646-xhx9pzhj 2454 5 UCHIDA UCHIDA NNP cord-005646-xhx9pzhj 2454 6 , , , cord-005646-xhx9pzhj 2454 7 Masao Masao NNP cord-005646-xhx9pzhj 2454 8 KATAYAMA KATAYAMA NNP cord-005646-xhx9pzhj 2454 9 , , , cord-005646-xhx9pzhj 2454 10 and and CC cord-005646-xhx9pzhj 2454 11 Rika Rika NNP cord-005646-xhx9pzhj 2454 12 MUTO MUTO NNP cord-005646-xhx9pzhj 2454 13 Department Department NNP cord-005646-xhx9pzhj 2454 14 of of IN cord-005646-xhx9pzhj 2454 15 Anesthesia Anesthesia NNP cord-005646-xhx9pzhj 2454 16 and and CC cord-005646-xhx9pzhj 2454 17 Critical Critical NNP cord-005646-xhx9pzhj 2454 18 Care Care NNP cord-005646-xhx9pzhj 2454 19 Medicine Medicine NNP cord-005646-xhx9pzhj 2455 1 Chiba Chiba NNP cord-005646-xhx9pzhj 2455 2 Children Children NNP cord-005646-xhx9pzhj 2455 3 's 's POS cord-005646-xhx9pzhj 2455 4 Hospital Hospital NNP cord-005646-xhx9pzhj 2455 5 , , , cord-005646-xhx9pzhj 2455 6 Chiba Chiba NNP cord-005646-xhx9pzhj 2455 7 City City NNP cord-005646-xhx9pzhj 2455 8 , , , cord-005646-xhx9pzhj 2455 9 Japan Japan NNP cord-005646-xhx9pzhj 2455 10 . . . cord-005646-xhx9pzhj 2456 1 Purpose purpose NN cord-005646-xhx9pzhj 2456 2 : : : cord-005646-xhx9pzhj 2457 1 This this DT cord-005646-xhx9pzhj 2457 2 study study NN cord-005646-xhx9pzhj 2457 3 was be VBD cord-005646-xhx9pzhj 2457 4 made make VBN cord-005646-xhx9pzhj 2457 5 to to TO cord-005646-xhx9pzhj 2457 6 find find VB cord-005646-xhx9pzhj 2457 7 out out RP cord-005646-xhx9pzhj 2457 8 whether whether IN cord-005646-xhx9pzhj 2457 9 the the DT cord-005646-xhx9pzhj 2457 10 heat heat NN cord-005646-xhx9pzhj 2457 11 and and CC cord-005646-xhx9pzhj 2457 12 moisture moisture NN cord-005646-xhx9pzhj 2457 13 exchangers exchanger NNS cord-005646-xhx9pzhj 2457 14 ( ( -LRB- cord-005646-xhx9pzhj 2457 15 HME HME NNP cord-005646-xhx9pzhj 2457 16 ) ) -RRB- cord-005646-xhx9pzhj 2457 17 was be VBD cord-005646-xhx9pzhj 2457 18 effective effective JJ cord-005646-xhx9pzhj 2457 19 enough enough RB cord-005646-xhx9pzhj 2457 20 to to TO cord-005646-xhx9pzhj 2457 21 humidify humidify VB cord-005646-xhx9pzhj 2457 22 in in IN cord-005646-xhx9pzhj 2457 23 the the DT cord-005646-xhx9pzhj 2457 24 respiratory respiratory JJ cord-005646-xhx9pzhj 2457 25 management management NN cord-005646-xhx9pzhj 2457 26 for for IN cord-005646-xhx9pzhj 2457 27 children child NNS cord-005646-xhx9pzhj 2457 28 . . . cord-005646-xhx9pzhj 2458 1 Patients patient NNS cord-005646-xhx9pzhj 2458 2 : : : cord-005646-xhx9pzhj 2459 1 The the DT cord-005646-xhx9pzhj 2459 2 study study NN cord-005646-xhx9pzhj 2459 3 population population NN cord-005646-xhx9pzhj 2459 4 consisted consist VBD cord-005646-xhx9pzhj 2459 5 of of IN cord-005646-xhx9pzhj 2459 6 21 21 CD cord-005646-xhx9pzhj 2459 7 patients patient NNS cord-005646-xhx9pzhj 2459 8 who who WP cord-005646-xhx9pzhj 2459 9 were be VBD cord-005646-xhx9pzhj 2459 10 provided provide VBN cord-005646-xhx9pzhj 2459 11 with with IN cord-005646-xhx9pzhj 2459 12 artificial artificial JJ cord-005646-xhx9pzhj 2459 13 airway airway NN cord-005646-xhx9pzhj 2459 14 . . . cord-005646-xhx9pzhj 2460 1 They -PRON- PRP cord-005646-xhx9pzhj 2460 2 were be VBD cord-005646-xhx9pzhj 2460 3 divided divide VBN cord-005646-xhx9pzhj 2460 4 into into IN cord-005646-xhx9pzhj 2460 5 the the DT cord-005646-xhx9pzhj 2460 6 two two CD cord-005646-xhx9pzhj 2460 7 groups group NNS cord-005646-xhx9pzhj 2460 8 : : : cord-005646-xhx9pzhj 2460 9 ii ii LS cord-005646-xhx9pzhj 2460 10 with with IN cord-005646-xhx9pzhj 2460 11 heated heated JJ cord-005646-xhx9pzhj 2460 12 humidifier humidifier NN cord-005646-xhx9pzhj 2460 13 ( ( -LRB- cord-005646-xhx9pzhj 2460 14 A a NN cord-005646-xhx9pzhj 2460 15 ) ) -RRB- cord-005646-xhx9pzhj 2460 16 and and CC cord-005646-xhx9pzhj 2460 17 i0 i0 NN cord-005646-xhx9pzhj 2460 18 with with IN cord-005646-xhx9pzhj 2460 19 HME HME NNP cord-005646-xhx9pzhj 2460 20 ( ( -LRB- cord-005646-xhx9pzhj 2460 21 B b NN cord-005646-xhx9pzhj 2460 22 ) ) -RRB- cord-005646-xhx9pzhj 2460 23 . . . cord-005646-xhx9pzhj 2461 1 Methods method NNS cord-005646-xhx9pzhj 2461 2 : : : cord-005646-xhx9pzhj 2461 3 HME HME NNP cord-005646-xhx9pzhj 2461 4 could could MD cord-005646-xhx9pzhj 2461 5 be be VB cord-005646-xhx9pzhj 2461 6 used use VBN cord-005646-xhx9pzhj 2461 7 for for IN cord-005646-xhx9pzhj 2461 8 those those DT cord-005646-xhx9pzhj 2461 9 without without IN cord-005646-xhx9pzhj 2461 10 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2461 11 complication complication NN cord-005646-xhx9pzhj 2461 12 and and CC cord-005646-xhx9pzhj 2461 13 with with IN cord-005646-xhx9pzhj 2461 14 less less JJR cord-005646-xhx9pzhj 2461 15 leakage leakage NN cord-005646-xhx9pzhj 2461 16 around around IN cord-005646-xhx9pzhj 2461 17 the the DT cord-005646-xhx9pzhj 2461 18 endotracheal endotracheal NN cord-005646-xhx9pzhj 2461 19 tube tube NN cord-005646-xhx9pzhj 2461 20 . . . cord-005646-xhx9pzhj 2462 1 In in IN cord-005646-xhx9pzhj 2462 2 both both CC cord-005646-xhx9pzhj 2462 3 A a NN cord-005646-xhx9pzhj 2462 4 and and CC cord-005646-xhx9pzhj 2462 5 B b NN cord-005646-xhx9pzhj 2462 6 groups group NNS cord-005646-xhx9pzhj 2462 7 , , , cord-005646-xhx9pzhj 2462 8 ( ( -LRB- cord-005646-xhx9pzhj 2462 9 i i NN cord-005646-xhx9pzhj 2462 10 ) ) -RRB- cord-005646-xhx9pzhj 2462 11 we -PRON- PRP cord-005646-xhx9pzhj 2462 12 have have VBP cord-005646-xhx9pzhj 2462 13 measured measure VBN cord-005646-xhx9pzhj 2462 14 relative relative JJ cord-005646-xhx9pzhj 2462 15 humidity humidity NN cord-005646-xhx9pzhj 2462 16 , , , cord-005646-xhx9pzhj 2462 17 temperature temperature NN cord-005646-xhx9pzhj 2462 18 , , , cord-005646-xhx9pzhj 2462 19 and and CC cord-005646-xhx9pzhj 2462 20 absolute absolute JJ cord-005646-xhx9pzhj 2462 21 humidity humidity NN cord-005646-xhx9pzhj 2462 22 at at IN cord-005646-xhx9pzhj 2462 23 the the DT cord-005646-xhx9pzhj 2462 24 endotracheal endotracheal NN cord-005646-xhx9pzhj 2462 25 tube tube NN cord-005646-xhx9pzhj 2462 26 connector connector NN cord-005646-xhx9pzhj 2462 27 . . . cord-005646-xhx9pzhj 2463 1 For for IN cord-005646-xhx9pzhj 2463 2 these these DT cord-005646-xhx9pzhj 2463 3 measurements measurement NNS cord-005646-xhx9pzhj 2463 4 , , , cord-005646-xhx9pzhj 2463 5 Humidity Humidity NNP cord-005646-xhx9pzhj 2463 6 Sensor Sensor NNP cord-005646-xhx9pzhj 2463 7 System System NNP cord-005646-xhx9pzhj 2463 8 was be VBD cord-005646-xhx9pzhj 2463 9 utilized utilize VBN cord-005646-xhx9pzhj 2463 10 . . . cord-005646-xhx9pzhj 2464 1 ( ( -LRB- cord-005646-xhx9pzhj 2464 2 2 2 LS cord-005646-xhx9pzhj 2464 3 ) ) -RRB- cord-005646-xhx9pzhj 2465 1 Any any DT cord-005646-xhx9pzhj 2465 2 troubles trouble NNS cord-005646-xhx9pzhj 2465 3 and and CC cord-005646-xhx9pzhj 2465 4 complications complication NNS cord-005646-xhx9pzhj 2465 5 caused cause VBN cord-005646-xhx9pzhj 2465 6 by by IN cord-005646-xhx9pzhj 2465 7 the the DT cord-005646-xhx9pzhj 2465 8 artificial artificial JJ cord-005646-xhx9pzhj 2465 9 airway airway NN cord-005646-xhx9pzhj 2465 10 were be VBD cord-005646-xhx9pzhj 2465 11 investigated investigate VBN cord-005646-xhx9pzhj 2465 12 . . . cord-005646-xhx9pzhj 2466 1 Results result NNS cord-005646-xhx9pzhj 2466 2 : : : cord-005646-xhx9pzhj 2466 3 ( ( -LRB- cord-005646-xhx9pzhj 2466 4 i i NN cord-005646-xhx9pzhj 2466 5 ) ) -RRB- cord-005646-xhx9pzhj 2467 1 In in IN cord-005646-xhx9pzhj 2467 2 Group Group NNP cord-005646-xhx9pzhj 2467 3 A A NNP cord-005646-xhx9pzhj 2467 4 , , , cord-005646-xhx9pzhj 2467 5 we -PRON- PRP cord-005646-xhx9pzhj 2467 6 confirmed confirm VBD cord-005646-xhx9pzhj 2467 7 the the DT cord-005646-xhx9pzhj 2467 8 mean mean JJ cord-005646-xhx9pzhj 2467 9 values value NNS cord-005646-xhx9pzhj 2467 10 as as IN cord-005646-xhx9pzhj 2467 11 the the DT cord-005646-xhx9pzhj 2467 12 relative relative JJ cord-005646-xhx9pzhj 2467 13 humidity humidity NN cord-005646-xhx9pzhj 2467 14 of of IN cord-005646-xhx9pzhj 2467 15 96.5 96.5 CD cord-005646-xhx9pzhj 2467 16 % % NN cord-005646-xhx9pzhj 2467 17 , , , cord-005646-xhx9pzhj 2467 18 the the DT cord-005646-xhx9pzhj 2467 19 temperature temperature NN cord-005646-xhx9pzhj 2467 20 of of IN cord-005646-xhx9pzhj 2467 21 32.8~C 32.8~C NNP cord-005646-xhx9pzhj 2467 22 , , , cord-005646-xhx9pzhj 2467 23 and and CC cord-005646-xhx9pzhj 2467 24 the the DT cord-005646-xhx9pzhj 2467 25 absolute absolute JJ cord-005646-xhx9pzhj 2467 26 humidity humidity NN cord-005646-xhx9pzhj 2467 27 of of IN cord-005646-xhx9pzhj 2467 28 34.0mg 34.0mg CD cord-005646-xhx9pzhj 2467 29 / / SYM cord-005646-xhx9pzhj 2467 30 L. L. NNP cord-005646-xhx9pzhj 2467 31 In in IN cord-005646-xhx9pzhj 2467 32 Group Group NNP cord-005646-xhx9pzhj 2467 33 B B NNP cord-005646-xhx9pzhj 2467 34 , , , cord-005646-xhx9pzhj 2467 35 they -PRON- PRP cord-005646-xhx9pzhj 2467 36 were be VBD cord-005646-xhx9pzhj 2467 37 92.7 92.7 CD cord-005646-xhx9pzhj 2467 38 % % NN cord-005646-xhx9pzhj 2467 39 , , , cord-005646-xhx9pzhj 2467 40 29.5 29.5 CD cord-005646-xhx9pzhj 2467 41 ° ° NN cord-005646-xhx9pzhj 2467 42 C c NN cord-005646-xhx9pzhj 2467 43 , , , cord-005646-xhx9pzhj 2467 44 and and CC cord-005646-xhx9pzhj 2467 45 28.7mg 28.7mg CD cord-005646-xhx9pzhj 2467 46 / / SYM cord-005646-xhx9pzhj 2467 47 L l NN cord-005646-xhx9pzhj 2467 48 respectively respectively RB cord-005646-xhx9pzhj 2467 49 . . . cord-005646-xhx9pzhj 2468 1 No no DT cord-005646-xhx9pzhj 2468 2 difference difference NN cord-005646-xhx9pzhj 2468 3 was be VBD cord-005646-xhx9pzhj 2468 4 noted note VBN cord-005646-xhx9pzhj 2468 5 between between IN cord-005646-xhx9pzhj 2468 6 the the DT cord-005646-xhx9pzhj 2468 7 two two CD cord-005646-xhx9pzhj 2468 8 groups group NNS cord-005646-xhx9pzhj 2468 9 as as IN cord-005646-xhx9pzhj 2468 10 to to IN cord-005646-xhx9pzhj 2468 11 the the DT cord-005646-xhx9pzhj 2468 12 relative relative JJ cord-005646-xhx9pzhj 2468 13 humidity humidity NN cord-005646-xhx9pzhj 2468 14 , , , cord-005646-xhx9pzhj 2468 15 but but CC cord-005646-xhx9pzhj 2468 16 the the DT cord-005646-xhx9pzhj 2468 17 temperature temperature NN cord-005646-xhx9pzhj 2468 18 and and CC cord-005646-xhx9pzhj 2468 19 absolute absolute JJ cord-005646-xhx9pzhj 2468 20 humidity humidity NN cord-005646-xhx9pzhj 2468 21 were be VBD cord-005646-xhx9pzhj 2468 22 lower low JJR cord-005646-xhx9pzhj 2468 23 in in IN cord-005646-xhx9pzhj 2468 24 Group Group NNP cord-005646-xhx9pzhj 2468 25 B B NNP cord-005646-xhx9pzhj 2468 26 with with IN cord-005646-xhx9pzhj 2468 27 a a DT cord-005646-xhx9pzhj 2468 28 significant significant JJ cord-005646-xhx9pzhj 2468 29 difference difference NN cord-005646-xhx9pzhj 2468 30 ( ( -LRB- cord-005646-xhx9pzhj 2468 31 p<0.0001 p<0.0001 NNP cord-005646-xhx9pzhj 2468 32 ) ) -RRB- cord-005646-xhx9pzhj 2468 33 . . . cord-005646-xhx9pzhj 2469 1 ( ( -LRB- cord-005646-xhx9pzhj 2469 2 2 2 LS cord-005646-xhx9pzhj 2469 3 ) ) -RRB- cord-005646-xhx9pzhj 2470 1 In in IN cord-005646-xhx9pzhj 2470 2 neither neither DT cord-005646-xhx9pzhj 2470 3 of of IN cord-005646-xhx9pzhj 2470 4 the the DT cord-005646-xhx9pzhj 2470 5 groups group NNS cord-005646-xhx9pzhj 2470 6 , , , cord-005646-xhx9pzhj 2470 7 any any DT cord-005646-xhx9pzhj 2470 8 respiratory respiratory JJ cord-005646-xhx9pzhj 2470 9 complications complication NNS cord-005646-xhx9pzhj 2470 10 such such JJ cord-005646-xhx9pzhj 2470 11 as as IN cord-005646-xhx9pzhj 2470 12 obstruction obstruction NN cord-005646-xhx9pzhj 2470 13 or or CC cord-005646-xhx9pzhj 2470 14 stenosis stenosis NN cord-005646-xhx9pzhj 2470 15 of of IN cord-005646-xhx9pzhj 2470 16 the the DT cord-005646-xhx9pzhj 2470 17 artificial artificial JJ cord-005646-xhx9pzhj 2470 18 airway airway NN cord-005646-xhx9pzhj 2470 19 were be VBD cord-005646-xhx9pzhj 2470 20 noted note VBN cord-005646-xhx9pzhj 2470 21 . . . cord-005646-xhx9pzhj 2471 1 In in IN cord-005646-xhx9pzhj 2471 2 pediatric pediatric JJ cord-005646-xhx9pzhj 2471 3 ICU ICU NNP cord-005646-xhx9pzhj 2471 4 , , , cord-005646-xhx9pzhj 2471 5 HME HME NNP cord-005646-xhx9pzhj 2471 6 can can MD cord-005646-xhx9pzhj 2471 7 be be VB cord-005646-xhx9pzhj 2471 8 used use VBN cord-005646-xhx9pzhj 2471 9 without without IN cord-005646-xhx9pzhj 2471 10 any any DT cord-005646-xhx9pzhj 2471 11 problems problem NNS cord-005646-xhx9pzhj 2471 12 under under IN cord-005646-xhx9pzhj 2471 13 given give VBN cord-005646-xhx9pzhj 2471 14 conditions condition NNS cord-005646-xhx9pzhj 2471 15 . . . cord-005646-xhx9pzhj 2472 1 Titei Titei NNP cord-005646-xhx9pzhj 2472 2 : : : cord-005646-xhx9pzhj 2473 1 Objective objective NN cord-005646-xhx9pzhj 2473 2 : : : cord-005646-xhx9pzhj 2473 3 evaluate evaluate VB cord-005646-xhx9pzhj 2473 4 the the DT cord-005646-xhx9pzhj 2473 5 precision precision NN cord-005646-xhx9pzhj 2473 6 , , , cord-005646-xhx9pzhj 2473 7 reproductibility reproductibility NN cord-005646-xhx9pzhj 2473 8 and and CC cord-005646-xhx9pzhj 2473 9 aplicability aplicability NN cord-005646-xhx9pzhj 2473 10 of of IN cord-005646-xhx9pzhj 2473 11 a a DT cord-005646-xhx9pzhj 2473 12 new new JJ cord-005646-xhx9pzhj 2473 13 device device NN cord-005646-xhx9pzhj 2473 14 to to TO cord-005646-xhx9pzhj 2473 15 measure measure VB cord-005646-xhx9pzhj 2473 16 auto auto NN cord-005646-xhx9pzhj 2473 17 - - HYPH cord-005646-xhx9pzhj 2473 18 PEEP peep NN cord-005646-xhx9pzhj 2473 19 in in IN cord-005646-xhx9pzhj 2473 20 pediatric pediatric JJ cord-005646-xhx9pzhj 2473 21 patients patient NNS cord-005646-xhx9pzhj 2473 22 during during IN cord-005646-xhx9pzhj 2473 23 mechanical mechanical JJ cord-005646-xhx9pzhj 2473 24 ventilation ventilation NN cord-005646-xhx9pzhj 2473 25 . . . cord-005646-xhx9pzhj 2474 1 Material material NN cord-005646-xhx9pzhj 2474 2 and and CC cord-005646-xhx9pzhj 2474 3 Methods method NNS cord-005646-xhx9pzhj 2474 4 : : : cord-005646-xhx9pzhj 2474 5 it -PRON- PRP cord-005646-xhx9pzhj 2474 6 's be VBZ cord-005646-xhx9pzhj 2474 7 an an DT cord-005646-xhx9pzhj 2474 8 electromc electromc JJ cord-005646-xhx9pzhj 2474 9 - - HYPH cord-005646-xhx9pzhj 2474 10 pneumatic pneumatic JJ cord-005646-xhx9pzhj 2474 11 eontolled eontolled JJ cord-005646-xhx9pzhj 2474 12 device device NN cord-005646-xhx9pzhj 2474 13 with with IN cord-005646-xhx9pzhj 2474 14 an an DT cord-005646-xhx9pzhj 2474 15 oclusion oclusion NN cord-005646-xhx9pzhj 2474 16 valve valve NN cord-005646-xhx9pzhj 2474 17 and and CC cord-005646-xhx9pzhj 2474 18 a a DT cord-005646-xhx9pzhj 2474 19 pressure pressure NN cord-005646-xhx9pzhj 2474 20 monitor monitor NN cord-005646-xhx9pzhj 2474 21 installed instal VBN cord-005646-xhx9pzhj 2474 22 between between IN cord-005646-xhx9pzhj 2474 23 endotracheal endotracheal NN cord-005646-xhx9pzhj 2474 24 canulla canulla NNP cord-005646-xhx9pzhj 2474 25 and and CC cord-005646-xhx9pzhj 2474 26 the the DT cord-005646-xhx9pzhj 2474 27 ventilator ventilator NN cord-005646-xhx9pzhj 2474 28 circuit circuit NN cord-005646-xhx9pzhj 2474 29 . . . cord-005646-xhx9pzhj 2475 1 The the DT cord-005646-xhx9pzhj 2475 2 measurements measurement NNS cord-005646-xhx9pzhj 2475 3 were be VBD cord-005646-xhx9pzhj 2475 4 performed perform VBN cord-005646-xhx9pzhj 2475 5 with with IN cord-005646-xhx9pzhj 2475 6 a a DT cord-005646-xhx9pzhj 2475 7 sollenoid sollenoid JJ cord-005646-xhx9pzhj 2475 8 conected conecte VBN cord-005646-xhx9pzhj 2475 9 with with IN cord-005646-xhx9pzhj 2475 10 to to IN cord-005646-xhx9pzhj 2475 11 the the DT cord-005646-xhx9pzhj 2475 12 ventilator ventilator NN cord-005646-xhx9pzhj 2475 13 to to TO cord-005646-xhx9pzhj 2475 14 detect detect VB cord-005646-xhx9pzhj 2475 15 the the DT cord-005646-xhx9pzhj 2475 16 end end NN cord-005646-xhx9pzhj 2475 17 of of IN cord-005646-xhx9pzhj 2475 18 inspiration inspiration NN cord-005646-xhx9pzhj 2475 19 phase phase NN cord-005646-xhx9pzhj 2475 20 and and CC cord-005646-xhx9pzhj 2475 21 the the DT cord-005646-xhx9pzhj 2475 22 actwation actwation NN cord-005646-xhx9pzhj 2475 23 of of IN cord-005646-xhx9pzhj 2475 24 the the DT cord-005646-xhx9pzhj 2475 25 oclusion oclusion NN cord-005646-xhx9pzhj 2475 26 valve valve NN cord-005646-xhx9pzhj 2475 27 . . . cord-005646-xhx9pzhj 2476 1 The the DT cord-005646-xhx9pzhj 2476 2 signs sign NNS cord-005646-xhx9pzhj 2476 3 of of IN cord-005646-xhx9pzhj 2476 4 pressure pressure NN cord-005646-xhx9pzhj 2476 5 and and CC cord-005646-xhx9pzhj 2476 6 flow flow NN cord-005646-xhx9pzhj 2476 7 were be VBD cord-005646-xhx9pzhj 2476 8 moniturized moniturize VBN cord-005646-xhx9pzhj 2476 9 using use VBG cord-005646-xhx9pzhj 2476 10 a a DT cord-005646-xhx9pzhj 2476 11 difere difere JJ cord-005646-xhx9pzhj 2476 12 ~ ~ CD cord-005646-xhx9pzhj 2476 13 rtial rtial JJ cord-005646-xhx9pzhj 2476 14 transducer transducer NN cord-005646-xhx9pzhj 2476 15 and and CC cord-005646-xhx9pzhj 2476 16 it -PRON- PRP cord-005646-xhx9pzhj 2476 17 was be VBD cord-005646-xhx9pzhj 2476 18 processed process VBN cord-005646-xhx9pzhj 2476 19 using use VBG cord-005646-xhx9pzhj 2476 20 a a DT cord-005646-xhx9pzhj 2476 21 PC pc NN cord-005646-xhx9pzhj 2476 22 computer computer NN cord-005646-xhx9pzhj 2476 23 and and CC cord-005646-xhx9pzhj 2476 24 a a DT cord-005646-xhx9pzhj 2476 25 Pneumoviaw Pneumoviaw NNP cord-005646-xhx9pzhj 2476 26 ® ® NN cord-005646-xhx9pzhj 2476 27 software software NN cord-005646-xhx9pzhj 2476 28 . . . cord-005646-xhx9pzhj 2477 1 The the DT cord-005646-xhx9pzhj 2477 2 auto auto NN cord-005646-xhx9pzhj 2477 3 - - HYPH cord-005646-xhx9pzhj 2477 4 PEEP PEEP NNP cord-005646-xhx9pzhj 2477 5 also also RB cord-005646-xhx9pzhj 2477 6 displayed display VBD cord-005646-xhx9pzhj 2477 7 in in IN cord-005646-xhx9pzhj 2477 8 the the DT cord-005646-xhx9pzhj 2477 9 ventilator ventilator NN cord-005646-xhx9pzhj 2477 10 pressure pressure NN cord-005646-xhx9pzhj 2477 11 monitor monitor NN cord-005646-xhx9pzhj 2477 12 . . . cord-005646-xhx9pzhj 2478 1 Results result NNS cord-005646-xhx9pzhj 2478 2 : : : cord-005646-xhx9pzhj 2478 3 we -PRON- PRP cord-005646-xhx9pzhj 2478 4 submitted submit VBD cord-005646-xhx9pzhj 2478 5 17 17 CD cord-005646-xhx9pzhj 2478 6 children child NNS cord-005646-xhx9pzhj 2478 7 with with IN cord-005646-xhx9pzhj 2478 8 neuromuscular neuromuscular JJ cord-005646-xhx9pzhj 2478 9 disease disease NN cord-005646-xhx9pzhj 2478 10 or or CC cord-005646-xhx9pzhj 2478 11 respiratory respiratory JJ cord-005646-xhx9pzhj 2478 12 distress distress NN cord-005646-xhx9pzhj 2478 13 in in IN cord-005646-xhx9pzhj 2478 14 this this DT cord-005646-xhx9pzhj 2478 15 study study NN cord-005646-xhx9pzhj 2478 16 . . . cord-005646-xhx9pzhj 2479 1 The the DT cord-005646-xhx9pzhj 2479 2 incidence incidence NN cord-005646-xhx9pzhj 2479 3 of of IN cord-005646-xhx9pzhj 2479 4 auto auto NN cord-005646-xhx9pzhj 2479 5 - - HYPH cord-005646-xhx9pzhj 2479 6 PEEP PEEP NNP cord-005646-xhx9pzhj 2479 7 was be VBD cord-005646-xhx9pzhj 2479 8 76 76 CD cord-005646-xhx9pzhj 2479 9 % % NN cord-005646-xhx9pzhj 2479 10 , , , cord-005646-xhx9pzhj 2479 11 with with IN cord-005646-xhx9pzhj 2479 12 variability variability NN cord-005646-xhx9pzhj 2479 13 between between IN cord-005646-xhx9pzhj 2479 14 1,5 1,5 CD cord-005646-xhx9pzhj 2479 15 to to IN cord-005646-xhx9pzhj 2479 16 13 13 CD cord-005646-xhx9pzhj 2479 17 cmH20 cmH20 NNP cord-005646-xhx9pzhj 2479 18 . . . cord-005646-xhx9pzhj 2480 1 All all PDT cord-005646-xhx9pzhj 2480 2 the the DT cord-005646-xhx9pzhj 2480 3 measurements measurement NNS cord-005646-xhx9pzhj 2480 4 were be VBD cord-005646-xhx9pzhj 2480 5 performed perform VBN cord-005646-xhx9pzhj 2480 6 3 3 CD cord-005646-xhx9pzhj 2480 7 times time NNS cord-005646-xhx9pzhj 2480 8 to to TO cord-005646-xhx9pzhj 2480 9 verify verify VB cord-005646-xhx9pzhj 2480 10 the the DT cord-005646-xhx9pzhj 2480 11 precision precision NN cord-005646-xhx9pzhj 2480 12 and and CC cord-005646-xhx9pzhj 2480 13 the the DT cord-005646-xhx9pzhj 2480 14 reproduetibility reproduetibility NN cord-005646-xhx9pzhj 2480 15 and and CC cord-005646-xhx9pzhj 2480 16 evaluation evaluation NN cord-005646-xhx9pzhj 2480 17 of of IN cord-005646-xhx9pzhj 2480 18 the the DT cord-005646-xhx9pzhj 2480 19 pressure pressure NN cord-005646-xhx9pzhj 2480 20 and and CC cord-005646-xhx9pzhj 2480 21 flow flow NN cord-005646-xhx9pzhj 2480 22 curves curve NNS cord-005646-xhx9pzhj 2480 23 . . . cord-005646-xhx9pzhj 2481 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2481 2 : : : cord-005646-xhx9pzhj 2481 3 the the DT cord-005646-xhx9pzhj 2481 4 device device NN cord-005646-xhx9pzhj 2481 5 is be VBZ cord-005646-xhx9pzhj 2481 6 low low JJ cord-005646-xhx9pzhj 2481 7 cost cost NN cord-005646-xhx9pzhj 2481 8 , , , cord-005646-xhx9pzhj 2481 9 easy easy JJ cord-005646-xhx9pzhj 2481 10 to to TO cord-005646-xhx9pzhj 2481 11 use use VB cord-005646-xhx9pzhj 2481 12 and and CC cord-005646-xhx9pzhj 2481 13 can can MD cord-005646-xhx9pzhj 2481 14 be be VB cord-005646-xhx9pzhj 2481 15 used use VBN cord-005646-xhx9pzhj 2481 16 without without IN cord-005646-xhx9pzhj 2481 17 the the DT cord-005646-xhx9pzhj 2481 18 pneumotacograph pneumotacograph NN cord-005646-xhx9pzhj 2481 19 . . . cord-005646-xhx9pzhj 2482 1 The the DT cord-005646-xhx9pzhj 2482 2 auto auto NN cord-005646-xhx9pzhj 2482 3 - - HYPH cord-005646-xhx9pzhj 2482 4 PEEP peep NN cord-005646-xhx9pzhj 2482 5 measurement measurement NN cord-005646-xhx9pzhj 2482 6 can can MD cord-005646-xhx9pzhj 2482 7 be be VB cord-005646-xhx9pzhj 2482 8 done do VBN cord-005646-xhx9pzhj 2482 9 during during IN cord-005646-xhx9pzhj 2482 10 mechanical mechanical JJ cord-005646-xhx9pzhj 2482 11 ventilation ventilation NN cord-005646-xhx9pzhj 2482 12 with with IN cord-005646-xhx9pzhj 2482 13 time time NN cord-005646-xhx9pzhj 2482 14 cycled cycle VBN cord-005646-xhx9pzhj 2482 15 , , , cord-005646-xhx9pzhj 2482 16 pressure pressure NN cord-005646-xhx9pzhj 2482 17 limited limited JJ cord-005646-xhx9pzhj 2482 18 and and CC cord-005646-xhx9pzhj 2482 19 continuous continuous JJ cord-005646-xhx9pzhj 2482 20 flow flow NN cord-005646-xhx9pzhj 2482 21 , , , cord-005646-xhx9pzhj 2482 22 the the DT cord-005646-xhx9pzhj 2482 23 most most RBS cord-005646-xhx9pzhj 2482 24 commom commom JJ cord-005646-xhx9pzhj 2482 25 ventilator ventilator NN cord-005646-xhx9pzhj 2482 26 used use VBN cord-005646-xhx9pzhj 2482 27 in in IN cord-005646-xhx9pzhj 2482 28 pediatric pediatric JJ cord-005646-xhx9pzhj 2482 29 patient patient NN cord-005646-xhx9pzhj 2482 30 . . . cord-005646-xhx9pzhj 2482 31 _SP cord-005646-xhx9pzhj 2483 1 Resistance resistance NN cord-005646-xhx9pzhj 2483 2 was be VBD cord-005646-xhx9pzhj 2483 3 modeled model VBN cord-005646-xhx9pzhj 2483 4 by by IN cord-005646-xhx9pzhj 2483 5 3 3 CD cord-005646-xhx9pzhj 2483 6 endotracheal endotracheal NN cord-005646-xhx9pzhj 2483 7 tube tube NN cord-005646-xhx9pzhj 2483 8 ( ( -LRB- cord-005646-xhx9pzhj 2483 9 ETT ETT NNP cord-005646-xhx9pzhj 2483 10 ) ) -RRB- cord-005646-xhx9pzhj 2483 11 sizes size NNS cord-005646-xhx9pzhj 2483 12 ( ( -LRB- cord-005646-xhx9pzhj 2483 13 2.5 2.5 CD cord-005646-xhx9pzhj 2483 14 , , , cord-005646-xhx9pzhj 2483 15 3 3 CD cord-005646-xhx9pzhj 2483 16 , , , cord-005646-xhx9pzhj 2483 17 3,5 3,5 CD cord-005646-xhx9pzhj 2483 18 ) ) -RRB- cord-005646-xhx9pzhj 2483 19 , , , cord-005646-xhx9pzhj 2483 20 and and CC cord-005646-xhx9pzhj 2483 21 compliance compliance NN cord-005646-xhx9pzhj 2483 22 by by IN cord-005646-xhx9pzhj 2483 23 2 2 CD cord-005646-xhx9pzhj 2483 24 test test NN cord-005646-xhx9pzhj 2483 25 lungs lung NNS cord-005646-xhx9pzhj 2483 26 ( ( -LRB- cord-005646-xhx9pzhj 2483 27 1 1 CD cord-005646-xhx9pzhj 2483 28 and and CC cord-005646-xhx9pzhj 2483 29 5 5 CD cord-005646-xhx9pzhj 2483 30 ml ml NN cord-005646-xhx9pzhj 2483 31 / / SYM cord-005646-xhx9pzhj 2483 32 crnH20 crnh20 NN cord-005646-xhx9pzhj 2483 33 ) ) -RRB- cord-005646-xhx9pzhj 2483 34 , , . cord-005646-xhx9pzhj 2484 1 For for IN cord-005646-xhx9pzhj 2484 2 each each DT cord-005646-xhx9pzhj 2484 3 resistance resistance NN cord-005646-xhx9pzhj 2484 4 -compliance -compliance NN cord-005646-xhx9pzhj 2484 5 arrangement arrangement NN cord-005646-xhx9pzhj 2484 6 , , , cord-005646-xhx9pzhj 2484 7 we -PRON- PRP cord-005646-xhx9pzhj 2484 8 measured measure VBD cord-005646-xhx9pzhj 2484 9 tidal tidal JJ cord-005646-xhx9pzhj 2484 10 volume volume NN cord-005646-xhx9pzhj 2484 11 ( ( -LRB- cord-005646-xhx9pzhj 2484 12 Vt Vt NNP cord-005646-xhx9pzhj 2484 13 ) ) -RRB- cord-005646-xhx9pzhj 2484 14 at at IN cord-005646-xhx9pzhj 2484 15 various various JJ cord-005646-xhx9pzhj 2484 16 frequencies frequency NNS cord-005646-xhx9pzhj 2484 17 , , , cord-005646-xhx9pzhj 2484 18 peak peak NN cord-005646-xhx9pzhj 2484 19 to to IN cord-005646-xhx9pzhj 2484 20 peak peak NN cord-005646-xhx9pzhj 2484 21 ( ( -LRB- cord-005646-xhx9pzhj 2484 22 P p NN cord-005646-xhx9pzhj 2484 23 - - HYPH cord-005646-xhx9pzhj 2484 24 P p NN cord-005646-xhx9pzhj 2484 25 ) ) -RRB- cord-005646-xhx9pzhj 2484 26 and and CC cord-005646-xhx9pzhj 2484 27 mean mean VB cord-005646-xhx9pzhj 2484 28 airway airway NN cord-005646-xhx9pzhj 2484 29 pressures pressure NNS cord-005646-xhx9pzhj 2484 30 . . . cord-005646-xhx9pzhj 2485 1 Results Results NNP cord-005646-xhx9pzhj 2485 2 Vt Vt NNP cord-005646-xhx9pzhj 2485 3 increased increase VBD cord-005646-xhx9pzhj 2485 4 when when WRB cord-005646-xhx9pzhj 2485 5 ETT ETT NNP cord-005646-xhx9pzhj 2485 6 size size NN cord-005646-xhx9pzhj 2485 7 increased increase VBD cord-005646-xhx9pzhj 2485 8 with with IN cord-005646-xhx9pzhj 2485 9 all all DT cord-005646-xhx9pzhj 2485 10 3 3 CD cord-005646-xhx9pzhj 2485 11 ventilators ventilator NNS cord-005646-xhx9pzhj 2485 12 in in IN cord-005646-xhx9pzhj 2485 13 accordance accordance NN cord-005646-xhx9pzhj 2485 14 with with IN cord-005646-xhx9pzhj 2485 15 Fredberg Fredberg NNP cord-005646-xhx9pzhj 2485 16 results result NNS cord-005646-xhx9pzhj 2485 17 ( ( -LRB- cord-005646-xhx9pzhj 2485 18 JAP JAP NNP cord-005646-xhx9pzhj 2485 19 , , , cord-005646-xhx9pzhj 2485 20 1987 1987 CD cord-005646-xhx9pzhj 2485 21 ; ; : cord-005646-xhx9pzhj 2485 22 62 62 CD cord-005646-xhx9pzhj 2485 23 : : SYM cord-005646-xhx9pzhj 2485 24 2485 2485 CD cord-005646-xhx9pzhj 2485 25 - - SYM cord-005646-xhx9pzhj 2485 26 90 90 CD cord-005646-xhx9pzhj 2485 27 ) ) -RRB- cord-005646-xhx9pzhj 2485 28 . . . cord-005646-xhx9pzhj 2486 1 The the DT cord-005646-xhx9pzhj 2486 2 maximum maximum JJ cord-005646-xhx9pzhj 2486 3 Vt Vt NNP cord-005646-xhx9pzhj 2486 4 delivered deliver VBD cord-005646-xhx9pzhj 2486 5 was be VBD cord-005646-xhx9pzhj 2486 6 smaller small JJR cord-005646-xhx9pzhj 2486 7 with with IN cord-005646-xhx9pzhj 2486 8 the the DT cord-005646-xhx9pzhj 2486 9 HFV hfv NN cord-005646-xhx9pzhj 2486 10 - - HYPH cord-005646-xhx9pzhj 2486 11 Babyiog Babyiog NNP cord-005646-xhx9pzhj 2486 12 8000 8000 CD cord-005646-xhx9pzhj 2486 13 than than IN cord-005646-xhx9pzhj 2486 14 with with IN cord-005646-xhx9pzhj 2486 15 the the DT cord-005646-xhx9pzhj 2486 16 OHF OHF NNP cord-005646-xhx9pzhj 2486 17 1 1 CD cord-005646-xhx9pzhj 2486 18 or or CC cord-005646-xhx9pzhj 2486 19 the the DT cord-005646-xhx9pzhj 2486 20 SM SM NNP cord-005646-xhx9pzhj 2486 21 3100A 3100A NNS cord-005646-xhx9pzhj 2486 22 at at IN cord-005646-xhx9pzhj 2486 23 a a DT cord-005646-xhx9pzhj 2486 24 given give VBN cord-005646-xhx9pzhj 2486 25 frequency frequency NN cord-005646-xhx9pzhj 2486 26 ( ( -LRB- cord-005646-xhx9pzhj 2486 27 figure figure NN cord-005646-xhx9pzhj 2486 28 on on IN cord-005646-xhx9pzhj 2486 29 the the DT cord-005646-xhx9pzhj 2486 30 left left NN cord-005646-xhx9pzhj 2486 31 ) ) -RRB- cord-005646-xhx9pzhj 2486 32 . . . cord-005646-xhx9pzhj 2487 1 Increasing increase VBG cord-005646-xhx9pzhj 2487 2 P p NN cord-005646-xhx9pzhj 2487 3 - - HYPH cord-005646-xhx9pzhj 2487 4 P p NN cord-005646-xhx9pzhj 2487 5 resulted result VBD cord-005646-xhx9pzhj 2487 6 in in IN cord-005646-xhx9pzhj 2487 7 a a DT cord-005646-xhx9pzhj 2487 8 linear linear JJ cord-005646-xhx9pzhj 2487 9 increase increase NN cord-005646-xhx9pzhj 2487 10 in in IN cord-005646-xhx9pzhj 2487 11 Vt Vt NNP cord-005646-xhx9pzhj 2487 12 delivery delivery NN cord-005646-xhx9pzhj 2487 13 in in IN cord-005646-xhx9pzhj 2487 14 the the DT cord-005646-xhx9pzhj 2487 15 0 0 CD cord-005646-xhx9pzhj 2487 16 - - SYM cord-005646-xhx9pzhj 2487 17 30 30 CD cord-005646-xhx9pzhj 2487 18 % % NN cord-005646-xhx9pzhj 2487 19 range range NN cord-005646-xhx9pzhj 2487 20 of of IN cord-005646-xhx9pzhj 2487 21 maximum maximum JJ cord-005646-xhx9pzhj 2487 22 P p NN cord-005646-xhx9pzhj 2487 23 - - HYPH cord-005646-xhx9pzhj 2487 24 P p NN cord-005646-xhx9pzhj 2487 25 ( ( -LRB- cord-005646-xhx9pzhj 2487 26 figure figure NN cord-005646-xhx9pzhj 2487 27 on on IN cord-005646-xhx9pzhj 2487 28 the the DT cord-005646-xhx9pzhj 2487 29 right right NN cord-005646-xhx9pzhj 2487 30 ) ) -RRB- cord-005646-xhx9pzhj 2487 31 . . . cord-005646-xhx9pzhj 2488 1 HFV HFV NNP cord-005646-xhx9pzhj 2488 2 - - HYPH cord-005646-xhx9pzhj 2488 3 Babylog Babylog NNP cord-005646-xhx9pzhj 2488 4 8000 8000 CD cord-005646-xhx9pzhj 2488 5 did do VBD cord-005646-xhx9pzhj 2488 6 n't not RB cord-005646-xhx9pzhj 2488 7 provide provide VB cord-005646-xhx9pzhj 2488 8 significant significant JJ cord-005646-xhx9pzhj 2488 9 Vt Vt NNP cord-005646-xhx9pzhj 2488 10 increase increase NN cord-005646-xhx9pzhj 2488 11 when when WRB cord-005646-xhx9pzhj 2488 12 P p NN cord-005646-xhx9pzhj 2488 13 - - HYPH cord-005646-xhx9pzhj 2488 14 P p NN cord-005646-xhx9pzhj 2488 15 was be VBD cord-005646-xhx9pzhj 2488 16 set set VBN cord-005646-xhx9pzhj 2488 17 above above IN cord-005646-xhx9pzhj 2488 18 50 50 CD cord-005646-xhx9pzhj 2488 19 % % NN cord-005646-xhx9pzhj 2488 20 and and CC cord-005646-xhx9pzhj 2488 21 Vt Vt NNP cord-005646-xhx9pzhj 2488 22 deliven deliven NNP cord-005646-xhx9pzhj 2488 23 / / SYM cord-005646-xhx9pzhj 2488 24 decreased decrease VBD cord-005646-xhx9pzhj 2489 1 when when WRB cord-005646-xhx9pzhj 2489 2 mean mean JJ cord-005646-xhx9pzhj 2489 3 airway airway NN cord-005646-xhx9pzhj 2489 4 pressure pressure NN cord-005646-xhx9pzhj 2489 5 decreased decrease VBD cord-005646-xhx9pzhj 2489 6 . . . cord-005646-xhx9pzhj 2490 1 --i --i : cord-005646-xhx9pzhj 2491 1 5~ 5~ CD cord-005646-xhx9pzhj 2491 2 SM SM NNP cord-005646-xhx9pzhj 2491 3 3100A 3100A NNS cord-005646-xhx9pzhj 2492 1 A a DT cord-005646-xhx9pzhj 2492 2 number number NN cord-005646-xhx9pzhj 2492 3 of of IN cord-005646-xhx9pzhj 2492 4 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2492 5 parameters parameter NNS cord-005646-xhx9pzhj 2492 6 had have VBD cord-005646-xhx9pzhj 2492 7 been be VBN cord-005646-xhx9pzhj 2492 8 analyzed analyze VBN cord-005646-xhx9pzhj 2492 9 with with IN cord-005646-xhx9pzhj 2492 10 Russia Russia NNP cord-005646-xhx9pzhj 2492 11 - - HYPH cord-005646-xhx9pzhj 2492 12 produced produce VBN cord-005646-xhx9pzhj 2492 13 monitor monitor NN cord-005646-xhx9pzhj 2492 14 Humitemp Humitemp NNP cord-005646-xhx9pzhj 2492 15 HTM HTM NNP cord-005646-xhx9pzhj 2492 16 902 902 CD cord-005646-xhx9pzhj 2493 1 ( ( -LRB- cord-005646-xhx9pzhj 2493 2 Servisinstrument Servisinstrument NNP cord-005646-xhx9pzhj 2493 3 J,-S. J,-S. NNP cord-005646-xhx9pzhj 2493 4 Co Co NNP cord-005646-xhx9pzhj 2493 5 ) ) -RRB- cord-005646-xhx9pzhj 2493 6 in in IN cord-005646-xhx9pzhj 2493 7 24 24 CD cord-005646-xhx9pzhj 2493 8 newborn newborn JJ cord-005646-xhx9pzhj 2493 9 infants infant NNS cord-005646-xhx9pzhj 2493 10 with with IN cord-005646-xhx9pzhj 2493 11 RDSN RDSN NNP cord-005646-xhx9pzhj 2493 12 of of IN cord-005646-xhx9pzhj 2493 13 t t NNP cord-005646-xhx9pzhj 2493 14 - - HYPH cord-005646-xhx9pzhj 2493 15 IV IV NNP cord-005646-xhx9pzhj 2493 16 stages stage NNS cord-005646-xhx9pzhj 2493 17 on on IN cord-005646-xhx9pzhj 2493 18 CMV CMV NNP cord-005646-xhx9pzhj 2493 19 , , , cord-005646-xhx9pzhj 2493 20 CPPV CPPV NNP cord-005646-xhx9pzhj 2493 21 , , , cord-005646-xhx9pzhj 2493 22 IMV IMV NNP cord-005646-xhx9pzhj 2493 23 , , , cord-005646-xhx9pzhj 2493 24 and and CC cord-005646-xhx9pzhj 2493 25 CPAP CPAP NNP cord-005646-xhx9pzhj 2493 26 steps step NNS cord-005646-xhx9pzhj 2493 27 using use VBG cord-005646-xhx9pzhj 2493 28 respirators respirator NNS cord-005646-xhx9pzhj 2493 29 of of IN cord-005646-xhx9pzhj 2493 30 various various JJ cord-005646-xhx9pzhj 2493 31 kinds kind NNS cord-005646-xhx9pzhj 2493 32 ( ( -LRB- cord-005646-xhx9pzhj 2493 33 Stephan Stephan NNP cord-005646-xhx9pzhj 2493 34 - - HYPH cord-005646-xhx9pzhj 2493 35 Staxel Staxel NNP cord-005646-xhx9pzhj 2493 36 , , , cord-005646-xhx9pzhj 2493 37 Bear-2001 bear-2001 PRP cord-005646-xhx9pzhj 2493 38 , , , cord-005646-xhx9pzhj 2493 39 Newport Newport NNP cord-005646-xhx9pzhj 2493 40 8rezee 8rezee CD cord-005646-xhx9pzhj 2493 41 , , , cord-005646-xhx9pzhj 2493 42 Sechrist Sechrist NNP cord-005646-xhx9pzhj 2493 43 ) ) -RRB- cord-005646-xhx9pzhj 2493 44 . . . cord-005646-xhx9pzhj 2494 1 Parameters parameter NNS cord-005646-xhx9pzhj 2494 2 investigated investigate VBN cord-005646-xhx9pzhj 2494 3 were be VBD cord-005646-xhx9pzhj 2494 4 : : : cord-005646-xhx9pzhj 2494 5 temperature temperature NN cord-005646-xhx9pzhj 2494 6 of of IN cord-005646-xhx9pzhj 2494 7 inspired inspire VBN cord-005646-xhx9pzhj 2494 8 mixture mixture NN cord-005646-xhx9pzhj 2494 9 ( ( -LRB- cord-005646-xhx9pzhj 2494 10 T T NNP cord-005646-xhx9pzhj 2494 11 ) ) -RRB- cord-005646-xhx9pzhj 2494 12 , , , cord-005646-xhx9pzhj 2494 13 relative relative JJ cord-005646-xhx9pzhj 2494 14 and and CC cord-005646-xhx9pzhj 2494 15 absolute absolute JJ cord-005646-xhx9pzhj 2494 16 humidity humidity NN cord-005646-xhx9pzhj 2494 17 ( ( -LRB- cord-005646-xhx9pzhj 2494 18 RH RH NNP cord-005646-xhx9pzhj 2494 19 and and CC cord-005646-xhx9pzhj 2494 20 AH AH NNP cord-005646-xhx9pzhj 2494 21 , , , cord-005646-xhx9pzhj 2494 22 respectively respectively RB cord-005646-xhx9pzhj 2494 23 ) ) -RRB- cord-005646-xhx9pzhj 2494 24 , , , cord-005646-xhx9pzhj 2494 25 static static JJ cord-005646-xhx9pzhj 2494 26 compliance compliance NN cord-005646-xhx9pzhj 2494 27 ( ( -LRB- cord-005646-xhx9pzhj 2494 28 C C NNP cord-005646-xhx9pzhj 2494 29 ) ) -RRB- cord-005646-xhx9pzhj 2494 30 , , , cord-005646-xhx9pzhj 2494 31 expired expire VBD cord-005646-xhx9pzhj 2494 32 tidital tidital JJ cord-005646-xhx9pzhj 2494 33 volume volume NN cord-005646-xhx9pzhj 2494 34 ( ( -LRB- cord-005646-xhx9pzhj 2494 35 Vte Vte NNP cord-005646-xhx9pzhj 2494 36 ) ) -RRB- cord-005646-xhx9pzhj 2494 37 , , , cord-005646-xhx9pzhj 2494 38 expired expire VBD cord-005646-xhx9pzhj 2494 39 minute minute NN cord-005646-xhx9pzhj 2494 40 volume volume NN cord-005646-xhx9pzhj 2494 41 of of IN cord-005646-xhx9pzhj 2494 42 ventilation ventilation NN cord-005646-xhx9pzhj 2494 43 ( ( -LRB- cord-005646-xhx9pzhj 2494 44 MVe MVe NNS cord-005646-xhx9pzhj 2494 45 ) ) -RRB- cord-005646-xhx9pzhj 2494 46 . . . cord-005646-xhx9pzhj 2495 1 The the DT cord-005646-xhx9pzhj 2495 2 monitor monitor NN cord-005646-xhx9pzhj 2495 3 read read VBD cord-005646-xhx9pzhj 2495 4 these these DT cord-005646-xhx9pzhj 2495 5 parameters parameter NNS cord-005646-xhx9pzhj 2495 6 in in IN cord-005646-xhx9pzhj 2495 7 following follow VBG cord-005646-xhx9pzhj 2495 8 ranges range NNS cord-005646-xhx9pzhj 2495 9 ; ; : cord-005646-xhx9pzhj 2495 10 RH RH NNP cord-005646-xhx9pzhj 2495 11 - - : cord-005646-xhx9pzhj 2495 12 from from IN cord-005646-xhx9pzhj 2495 13 10 10 CD cord-005646-xhx9pzhj 2495 14 to to TO cord-005646-xhx9pzhj 2495 15 100 100 CD cord-005646-xhx9pzhj 2495 16 % % NN cord-005646-xhx9pzhj 2495 17 ; ; : cord-005646-xhx9pzhj 2495 18 AH ah NN cord-005646-xhx9pzhj 2495 19 - - HYPH cord-005646-xhx9pzhj 2495 20 up up NN cord-005646-xhx9pzhj 2495 21 to to IN cord-005646-xhx9pzhj 2495 22 55mg/ 55mg/ CD cord-005646-xhx9pzhj 2496 1 I -PRON- PRP cord-005646-xhx9pzhj 2496 2 ; ; : cord-005646-xhx9pzhj 2496 3 MVe MVe NNS cord-005646-xhx9pzhj 2496 4 - - HYPH cord-005646-xhx9pzhj 2496 5 up up NN cord-005646-xhx9pzhj 2497 1 to to IN cord-005646-xhx9pzhj 2497 2 3.0 3.0 CD cord-005646-xhx9pzhj 2498 1 I -PRON- PRP cord-005646-xhx9pzhj 2498 2 / / SYM cord-005646-xhx9pzhj 2498 3 mini mini JJ cord-005646-xhx9pzhj 2498 4 Vte Vte NNP cord-005646-xhx9pzhj 2498 5 - - : cord-005646-xhx9pzhj 2498 6 from from IN cord-005646-xhx9pzhj 2498 7 3 3 CD cord-005646-xhx9pzhj 2498 8 to to IN cord-005646-xhx9pzhj 2498 9 130 130 CD cord-005646-xhx9pzhj 2498 10 ml ml NNS cord-005646-xhx9pzhj 2498 11 ; ; : cord-005646-xhx9pzhj 2498 12 T t NN cord-005646-xhx9pzhj 2498 13 - - HYPH cord-005646-xhx9pzhj 2498 14 accurate accurate JJ cord-005646-xhx9pzhj 2498 15 to to IN cord-005646-xhx9pzhj 2498 16 3 3 CD cord-005646-xhx9pzhj 2498 17 % % NN cord-005646-xhx9pzhj 2498 18 ; ; : cord-005646-xhx9pzhj 2498 19 C c NN cord-005646-xhx9pzhj 2498 20 - - : cord-005646-xhx9pzhj 2498 21 from from IN cord-005646-xhx9pzhj 2498 22 0.1 0.1 CD cord-005646-xhx9pzhj 2498 23 to to TO cord-005646-xhx9pzhj 2498 24 t0 t0 VB cord-005646-xhx9pzhj 2498 25 ml ml NNP cord-005646-xhx9pzhj 2498 26 / / SYM cord-005646-xhx9pzhj 2498 27 cm cm NNP cord-005646-xhx9pzhj 2498 28 H20 H20 NNP cord-005646-xhx9pzhj 2498 29 . . . cord-005646-xhx9pzhj 2499 1 Continuous continuous JJ cord-005646-xhx9pzhj 2499 2 monitoring monitoring NN cord-005646-xhx9pzhj 2499 3 time time NN cord-005646-xhx9pzhj 2499 4 ranged range VBD cord-005646-xhx9pzhj 2499 5 from from IN cord-005646-xhx9pzhj 2499 6 2 2 CD cord-005646-xhx9pzhj 2499 7 to to TO cord-005646-xhx9pzhj 2499 8 96 96 CD cord-005646-xhx9pzhj 2499 9 hours hour NNS cord-005646-xhx9pzhj 2499 10 , , , cord-005646-xhx9pzhj 2499 11 it -PRON- PRP cord-005646-xhx9pzhj 2499 12 was be VBD cord-005646-xhx9pzhj 2499 13 noted note VBN cord-005646-xhx9pzhj 2499 14 , , , cord-005646-xhx9pzhj 2499 15 that that IN cord-005646-xhx9pzhj 2499 16 during during IN cord-005646-xhx9pzhj 2499 17 this this DT cord-005646-xhx9pzhj 2499 18 time time NN cord-005646-xhx9pzhj 2499 19 the the DT cord-005646-xhx9pzhj 2499 20 monitor monitor NN cord-005646-xhx9pzhj 2499 21 and and CC cord-005646-xhx9pzhj 2499 22 transducers transducer NNS cord-005646-xhx9pzhj 2499 23 had have VBD cord-005646-xhx9pzhj 2499 24 no no DT cord-005646-xhx9pzhj 2499 25 malfunctions malfunction NNS cord-005646-xhx9pzhj 2499 26 , , , cord-005646-xhx9pzhj 2499 27 and and CC cord-005646-xhx9pzhj 2499 28 it -PRON- PRP cord-005646-xhx9pzhj 2499 29 's be VBZ cord-005646-xhx9pzhj 2499 30 using use VBG cord-005646-xhx9pzhj 2499 31 did do VBD cord-005646-xhx9pzhj 2499 32 n't not RB cord-005646-xhx9pzhj 2499 33 require require VB cord-005646-xhx9pzhj 2499 34 additional additional JJ cord-005646-xhx9pzhj 2499 35 calibration calibration NN cord-005646-xhx9pzhj 2499 36 , , , cord-005646-xhx9pzhj 2499 37 it -PRON- PRP cord-005646-xhx9pzhj 2499 38 was be VBD cord-005646-xhx9pzhj 2499 39 found find VBN cord-005646-xhx9pzhj 2499 40 , , , cord-005646-xhx9pzhj 2499 41 that that IN cord-005646-xhx9pzhj 2499 42 humidifiers humidifier NNS cord-005646-xhx9pzhj 2499 43 MR MR NNP cord-005646-xhx9pzhj 2499 44 498 498 CD cord-005646-xhx9pzhj 2499 45 and and CC cord-005646-xhx9pzhj 2499 46 MR MR NNP cord-005646-xhx9pzhj 2499 47 410 410 CD cord-005646-xhx9pzhj 2500 1 ( ( -LRB- cord-005646-xhx9pzhj 2500 2 Fisher Fisher NNP cord-005646-xhx9pzhj 2500 3 , , , cord-005646-xhx9pzhj 2500 4 Paykel Paykel NNP cord-005646-xhx9pzhj 2500 5 ) ) -RRB- cord-005646-xhx9pzhj 2500 6 could could MD cord-005646-xhx9pzhj 2500 7 n't not RB cord-005646-xhx9pzhj 2500 8 maintain maintain VB cord-005646-xhx9pzhj 2500 9 parameters parameter NNS cord-005646-xhx9pzhj 2500 10 T t NN cord-005646-xhx9pzhj 2500 11 and and CC cord-005646-xhx9pzhj 2500 12 AH AH NNP cord-005646-xhx9pzhj 2500 13 continuously continuously RB cord-005646-xhx9pzhj 2500 14 ( ( -LRB- cord-005646-xhx9pzhj 2500 15 these these DT cord-005646-xhx9pzhj 2500 16 values value NNS cord-005646-xhx9pzhj 2500 17 varied varied JJ cord-005646-xhx9pzhj 2500 18 from from IN cord-005646-xhx9pzhj 2500 19 34,3 34,3 CD cord-005646-xhx9pzhj 2500 20 to to IN cord-005646-xhx9pzhj 2500 21 38.2 38.2 CD cord-005646-xhx9pzhj 2500 22 C C NNP cord-005646-xhx9pzhj 2500 23 and and CC cord-005646-xhx9pzhj 2500 24 from from IN cord-005646-xhx9pzhj 2500 25 37,5 37,5 CD cord-005646-xhx9pzhj 2500 26 to to IN cord-005646-xhx9pzhj 2500 27 47.1 47.1 CD cord-005646-xhx9pzhj 2500 28 mg mg NNP cord-005646-xhx9pzhj 2500 29 / / SYM cord-005646-xhx9pzhj 2500 30 I -PRON- PRP cord-005646-xhx9pzhj 2500 31 , , , cord-005646-xhx9pzhj 2500 32 respectively respectively RB cord-005646-xhx9pzhj 2500 33 , , , cord-005646-xhx9pzhj 2500 34 when when WRB cord-005646-xhx9pzhj 2500 35 heating heating NN cord-005646-xhx9pzhj 2500 36 regulator regulator NN cord-005646-xhx9pzhj 2500 37 position position NN cord-005646-xhx9pzhj 2500 38 was be VBD cord-005646-xhx9pzhj 2500 39 unchanged unchanged JJ cord-005646-xhx9pzhj 2500 40 ) ) -RRB- cord-005646-xhx9pzhj 2500 41 . . . cord-005646-xhx9pzhj 2501 1 Changes change NNS cord-005646-xhx9pzhj 2501 2 of of IN cord-005646-xhx9pzhj 2501 3 parameters parameter NNS cord-005646-xhx9pzhj 2501 4 C c NN cord-005646-xhx9pzhj 2501 5 depended depend VBD cord-005646-xhx9pzhj 2501 6 clearly clearly RB cord-005646-xhx9pzhj 2501 7 on on IN cord-005646-xhx9pzhj 2501 8 CPPV CPPV NNP cord-005646-xhx9pzhj 2501 9 conditions condition NNS cord-005646-xhx9pzhj 2501 10 and and CC cord-005646-xhx9pzhj 2501 11 RDSN RDSN NNP cord-005646-xhx9pzhj 2501 12 severity severity NN cord-005646-xhx9pzhj 2501 13 ( ( -LRB- cord-005646-xhx9pzhj 2501 14 with with IN cord-005646-xhx9pzhj 2501 15 RDSN RDSN NNP cord-005646-xhx9pzhj 2501 16 of of IN cord-005646-xhx9pzhj 2501 17 stages stage NNS cord-005646-xhx9pzhj 2502 1 I -PRON- PRP cord-005646-xhx9pzhj 2502 2 - - HYPH cord-005646-xhx9pzhj 2502 3 II II NNP cord-005646-xhx9pzhj 2502 4 C c NN cord-005646-xhx9pzhj 2502 5 value value NN cord-005646-xhx9pzhj 2502 6 ranged range VBD cord-005646-xhx9pzhj 2502 7 from from IN cord-005646-xhx9pzhj 2502 8 2.4 2.4 CD cord-005646-xhx9pzhj 2502 9 to to TO cord-005646-xhx9pzhj 2502 10 1.2 1.2 CD cord-005646-xhx9pzhj 2502 11 ml ml NNS cord-005646-xhx9pzhj 2502 12 / / SYM cord-005646-xhx9pzhj 2502 13 cm cm NN cord-005646-xhx9pzhj 2502 14 H20 H20 NNP cord-005646-xhx9pzhj 2502 15 ; ; : cord-005646-xhx9pzhj 2502 16 and and CC cord-005646-xhx9pzhj 2502 17 with with IN cord-005646-xhx9pzhj 2502 18 stages stage NNS cord-005646-xhx9pzhj 2502 19 IIt IIt NNP cord-005646-xhx9pzhj 2502 20 - - HYPH cord-005646-xhx9pzhj 2502 21 tV tV NNP cord-005646-xhx9pzhj 2502 22 - - : cord-005646-xhx9pzhj 2502 23 from from IN cord-005646-xhx9pzhj 2502 24 0.3 0.3 CD cord-005646-xhx9pzhj 2502 25 to to IN cord-005646-xhx9pzhj 2502 26 1.1 1.1 CD cord-005646-xhx9pzhj 2502 27 ) ) -RRB- cord-005646-xhx9pzhj 2502 28 . . . cord-005646-xhx9pzhj 2503 1 tn tn NNP cord-005646-xhx9pzhj 2503 2 6 6 CD cord-005646-xhx9pzhj 2503 3 newborn newborn JJ cord-005646-xhx9pzhj 2503 4 suffering suffering NN cord-005646-xhx9pzhj 2503 5 from from IN cord-005646-xhx9pzhj 2503 6 RDSN RDSN NNP cord-005646-xhx9pzhj 2503 7 of of IN cord-005646-xhx9pzhj 2503 8 stages stage NNS cord-005646-xhx9pzhj 2503 9 II II NNP cord-005646-xhx9pzhj 2503 10 - - HYPH cord-005646-xhx9pzhj 2503 11 ltl ltl NN cord-005646-xhx9pzhj 2503 12 and and CC cord-005646-xhx9pzhj 2503 13 Ill Ill NNP cord-005646-xhx9pzhj 2503 14 - - HYPH cord-005646-xhx9pzhj 2503 15 lV lV NNP cord-005646-xhx9pzhj 2503 16 with with IN cord-005646-xhx9pzhj 2503 17 PIP>25 pip>25 JJ cord-005646-xhx9pzhj 2503 18 mbar mbar NN cord-005646-xhx9pzhj 2503 19 , , , cord-005646-xhx9pzhj 2503 20 Fi02>0,7 fi02>0,7 NN cord-005646-xhx9pzhj 2503 21 , , , cord-005646-xhx9pzhj 2503 22 PEEP=4 peep=4 JJ cord-005646-xhx9pzhj 2503 23 - - HYPH cord-005646-xhx9pzhj 2503 24 7 7 CD cord-005646-xhx9pzhj 2503 25 mber mber NN cord-005646-xhx9pzhj 2503 26 , , , cord-005646-xhx9pzhj 2503 27 C C NNP cord-005646-xhx9pzhj 2503 28 - - : cord-005646-xhx9pzhj 2503 29 from from IN cord-005646-xhx9pzhj 2503 30 0.3 0.3 CD cord-005646-xhx9pzhj 2503 31 to to IN cord-005646-xhx9pzhj 2503 32 1.2 1.2 CD cord-005646-xhx9pzhj 2503 33 ml ml NNS cord-005646-xhx9pzhj 2503 34 / / SYM cord-005646-xhx9pzhj 2503 35 cm cm NNP cord-005646-xhx9pzhj 2503 36 H20 H20 NNP cord-005646-xhx9pzhj 2503 37 , , , cord-005646-xhx9pzhj 2503 38 effectivity effectivity NN cord-005646-xhx9pzhj 2503 39 of of IN cord-005646-xhx9pzhj 2503 40 Exosurf Exosurf NNP cord-005646-xhx9pzhj 2503 41 Therapy Therapy NNP cord-005646-xhx9pzhj 2503 42 was be VBD cord-005646-xhx9pzhj 2503 43 studied study VBN cord-005646-xhx9pzhj 2503 44 . . . cord-005646-xhx9pzhj 2504 1 In in IN cord-005646-xhx9pzhj 2504 2 4 4 CD cord-005646-xhx9pzhj 2504 3 newborns newborn NNS cord-005646-xhx9pzhj 2504 4 in in IN cord-005646-xhx9pzhj 2504 5 4 4 CD cord-005646-xhx9pzhj 2504 6 - - SYM cord-005646-xhx9pzhj 2504 7 12 12 CD cord-005646-xhx9pzhj 2504 8 hours hour NNS cord-005646-xhx9pzhj 2504 9 of of IN cord-005646-xhx9pzhj 2504 10 therapy therapy NN cord-005646-xhx9pzhj 2504 11 PIP PIP NNP cord-005646-xhx9pzhj 2504 12 decreased decrease VBD cord-005646-xhx9pzhj 2504 13 to to IN cord-005646-xhx9pzhj 2504 14 0.3 0.3 CD cord-005646-xhx9pzhj 2504 15 - - SYM cord-005646-xhx9pzhj 2504 16 0.4 0.4 CD cord-005646-xhx9pzhj 2504 17 , , , cord-005646-xhx9pzhj 2504 18 and and CC cord-005646-xhx9pzhj 2504 19 C C NNP cord-005646-xhx9pzhj 2504 20 increased increase VBD cord-005646-xhx9pzhj 2504 21 to to IN cord-005646-xhx9pzhj 2504 22 1,7 1,7 CD cord-005646-xhx9pzhj 2504 23 - - HYPH cord-005646-xhx9pzhj 2504 24 2.4 2.4 CD cord-005646-xhx9pzhj 2504 25 ml ml NN cord-005646-xhx9pzhj 2504 26 / / SYM cord-005646-xhx9pzhj 2504 27 cm cm NNP cord-005646-xhx9pzhj 2504 28 H20 H20 NNP cord-005646-xhx9pzhj 2504 29 . . . cord-005646-xhx9pzhj 2505 1 in in IN cord-005646-xhx9pzhj 2505 2 2 2 CD cord-005646-xhx9pzhj 2505 3 newborn newborn JJ cord-005646-xhx9pzhj 2505 4 infants infant NNS cord-005646-xhx9pzhj 2505 5 with with IN cord-005646-xhx9pzhj 2505 6 AaD02>500 AaD02>500 NNP cord-005646-xhx9pzhj 2505 7 mmHg mmHg NNP cord-005646-xhx9pzhj 2505 8 and and CC cord-005646-xhx9pzhj 2505 9 C c NN cord-005646-xhx9pzhj 2505 10 from from IN cord-005646-xhx9pzhj 2505 11 0,3 0,3 CD cord-005646-xhx9pzhj 2505 12 to to IN cord-005646-xhx9pzhj 2505 13 0.8 0.8 CD cord-005646-xhx9pzhj 2505 14 mltcm mltcm NN cord-005646-xhx9pzhj 2505 15 H20 H20 NNP cord-005646-xhx9pzhj 2505 16 positive positive JJ cord-005646-xhx9pzhj 2505 17 effects effect NNS cord-005646-xhx9pzhj 2505 18 of of IN cord-005646-xhx9pzhj 2505 19 Exosurf Exosurf NNP cord-005646-xhx9pzhj 2505 20 on on IN cord-005646-xhx9pzhj 2505 21 lung lung NN cord-005646-xhx9pzhj 2505 22 compliance compliance NN cord-005646-xhx9pzhj 2505 23 were be VBD cord-005646-xhx9pzhj 2505 24 not not RB cord-005646-xhx9pzhj 2505 25 observed observe VBN cord-005646-xhx9pzhj 2505 26 . . . cord-005646-xhx9pzhj 2506 1 In in IN cord-005646-xhx9pzhj 2506 2 3 3 CD cord-005646-xhx9pzhj 2506 3 newborns newborn NNS cord-005646-xhx9pzhj 2506 4 the the DT cord-005646-xhx9pzhj 2506 5 monitor monitor NN cord-005646-xhx9pzhj 2506 6 had have VBD cord-005646-xhx9pzhj 2506 7 revealed reveal VBN cord-005646-xhx9pzhj 2506 8 decreased decrease VBN cord-005646-xhx9pzhj 2506 9 of of IN cord-005646-xhx9pzhj 2506 10 C C NNP cord-005646-xhx9pzhj 2506 11 ( ( -LRB- cord-005646-xhx9pzhj 2506 12 from from IN cord-005646-xhx9pzhj 2506 13 3.4 3.4 CD cord-005646-xhx9pzhj 2506 14 - - SYM cord-005646-xhx9pzhj 2506 15 2.9 2.9 CD cord-005646-xhx9pzhj 2506 16 to to IN cord-005646-xhx9pzhj 2506 17 1,8 1,8 CD cord-005646-xhx9pzhj 2506 18 - - SYM cord-005646-xhx9pzhj 2506 19 1.3 1.3 CD cord-005646-xhx9pzhj 2506 20 ml ml NNS cord-005646-xhx9pzhj 2506 21 / / SYM cord-005646-xhx9pzhj 2506 22 cm cm NNP cord-005646-xhx9pzhj 2506 23 H20 H20 NNP cord-005646-xhx9pzhj 2506 24 ) ) -RRB- cord-005646-xhx9pzhj 2506 25 , , , cord-005646-xhx9pzhj 2506 26 manifested manifest VBN cord-005646-xhx9pzhj 2506 27 clinically clinically RB cord-005646-xhx9pzhj 2506 28 by by IN cord-005646-xhx9pzhj 2506 29 pneumothorax pneumothorax NN cord-005646-xhx9pzhj 2506 30 . . . cord-005646-xhx9pzhj 2507 1 In in IN cord-005646-xhx9pzhj 2507 2 general general JJ cord-005646-xhx9pzhj 2507 3 , , , cord-005646-xhx9pzhj 2507 4 monitor monitor VB cord-005646-xhx9pzhj 2507 5 HTM HTM NNP cord-005646-xhx9pzhj 2507 6 902 902 CD cord-005646-xhx9pzhj 2507 7 made make VBD cord-005646-xhx9pzhj 2507 8 possible possible JJ cord-005646-xhx9pzhj 2507 9 ; ; : cord-005646-xhx9pzhj 2507 10 1 1 LS cord-005646-xhx9pzhj 2507 11 ) ) -RRB- cord-005646-xhx9pzhj 2507 12 , , , cord-005646-xhx9pzhj 2507 13 to to TO cord-005646-xhx9pzhj 2507 14 estimate estimate VB cord-005646-xhx9pzhj 2507 15 the the DT cord-005646-xhx9pzhj 2507 16 adequacy adequacy NN cord-005646-xhx9pzhj 2507 17 of of IN cord-005646-xhx9pzhj 2507 18 CMV CMV NNP cord-005646-xhx9pzhj 2507 19 - - HYPH cord-005646-xhx9pzhj 2507 20 parameters parameter NNS cord-005646-xhx9pzhj 2507 21 and and CC cord-005646-xhx9pzhj 2507 22 regimes regime NNS cord-005646-xhx9pzhj 2507 23 in in IN cord-005646-xhx9pzhj 2507 24 newborn newborn JJ cord-005646-xhx9pzhj 2507 25 infants infant NNS cord-005646-xhx9pzhj 2507 26 ; ; : cord-005646-xhx9pzhj 2507 27 2 2 CD cord-005646-xhx9pzhj 2507 28 ) ) -RRB- cord-005646-xhx9pzhj 2507 29 . . . cord-005646-xhx9pzhj 2508 1 to to TO cord-005646-xhx9pzhj 2508 2 select select VB cord-005646-xhx9pzhj 2508 3 optimal optimal JJ cord-005646-xhx9pzhj 2508 4 T t NN cord-005646-xhx9pzhj 2508 5 and and CC cord-005646-xhx9pzhj 2508 6 AH AH NNP cord-005646-xhx9pzhj 2508 7 values value NNS cord-005646-xhx9pzhj 2508 8 in in IN cord-005646-xhx9pzhj 2508 9 the the DT cord-005646-xhx9pzhj 2508 10 respiratory respiratory JJ cord-005646-xhx9pzhj 2508 11 outline outline NN cord-005646-xhx9pzhj 2508 12 in in IN cord-005646-xhx9pzhj 2508 13 dependence dependence NN cord-005646-xhx9pzhj 2508 14 on on IN cord-005646-xhx9pzhj 2508 15 lung lung NN cord-005646-xhx9pzhj 2508 16 damage damage NN cord-005646-xhx9pzhj 2508 17 severity severity NN cord-005646-xhx9pzhj 2508 18 and and CC cord-005646-xhx9pzhj 2508 19 infused infuse VBN cord-005646-xhx9pzhj 2508 20 volume volume NN cord-005646-xhx9pzhj 2508 21 ; ; : cord-005646-xhx9pzhj 2508 22 3 3 CD cord-005646-xhx9pzhj 2508 23 ) ) -RRB- cord-005646-xhx9pzhj 2508 24 . . . cord-005646-xhx9pzhj 2509 1 to to TO cord-005646-xhx9pzhj 2509 2 reveal reveal VB cord-005646-xhx9pzhj 2509 3 RDSN RDSN NNP cord-005646-xhx9pzhj 2509 4 severity severity NN cord-005646-xhx9pzhj 2509 5 ; ; : cord-005646-xhx9pzhj 2509 6 4 4 LS cord-005646-xhx9pzhj 2509 7 ) ) -RRB- cord-005646-xhx9pzhj 2509 8 , , , cord-005646-xhx9pzhj 2509 9 to to TO cord-005646-xhx9pzhj 2509 10 optimize optimize VB cord-005646-xhx9pzhj 2509 11 indications indication NNS cord-005646-xhx9pzhj 2509 12 and and CC cord-005646-xhx9pzhj 2509 13 adequacy adequacy NN cord-005646-xhx9pzhj 2509 14 of of IN cord-005646-xhx9pzhj 2509 15 surfactaot surfactaot NNP cord-005646-xhx9pzhj 2509 16 therapy therapy NNP cord-005646-xhx9pzhj 2509 17 ; ; : cord-005646-xhx9pzhj 2509 18 5 5 CD cord-005646-xhx9pzhj 2509 19 ) ) -RRB- cord-005646-xhx9pzhj 2509 20 . . . cord-005646-xhx9pzhj 2510 1 to to TO cord-005646-xhx9pzhj 2510 2 diagnostieate diagnostieate VB cord-005646-xhx9pzhj 2510 3 the the DT cord-005646-xhx9pzhj 2510 4 air air NN cord-005646-xhx9pzhj 2510 5 leakage leakage NN cord-005646-xhx9pzhj 2510 6 syndrome syndrome NN cord-005646-xhx9pzhj 2510 7 ; ; : cord-005646-xhx9pzhj 2510 8 6 6 CD cord-005646-xhx9pzhj 2510 9 ) ) -RRB- cord-005646-xhx9pzhj 2510 10 . . . cord-005646-xhx9pzhj 2511 1 to to IN cord-005646-xhx9pzhj 2511 2 effects effect NNS cord-005646-xhx9pzhj 2511 3 to to IN cord-005646-xhx9pzhj 2511 4 some some DT cord-005646-xhx9pzhj 2511 5 agents agent NNS cord-005646-xhx9pzhj 2511 6 ( ( -LRB- cord-005646-xhx9pzhj 2511 7 broncholytics broncholytics NNP cord-005646-xhx9pzhj 2511 8 , , , cord-005646-xhx9pzhj 2511 9 spasmolytics spasmolytics NNP cord-005646-xhx9pzhj 2511 10 ) ) -RRB- cord-005646-xhx9pzhj 2511 11 ; ; : cord-005646-xhx9pzhj 2511 12 7 7 CD cord-005646-xhx9pzhj 2511 13 ) ) -RRB- cord-005646-xhx9pzhj 2511 14 . . . cord-005646-xhx9pzhj 2512 1 to to TO cord-005646-xhx9pzhj 2512 2 obtain obtain VB cord-005646-xhx9pzhj 2512 3 objective objective JJ cord-005646-xhx9pzhj 2512 4 indications indication NNS cord-005646-xhx9pzhj 2512 5 for for IN cord-005646-xhx9pzhj 2512 6 IMV IMV NNP cord-005646-xhx9pzhj 2512 7 / / SYM cord-005646-xhx9pzhj 2512 8 SIMV SIMV NNP cord-005646-xhx9pzhj 2512 9 and and CC cord-005646-xhx9pzhj 2512 10 CPAP CPAP NNP cord-005646-xhx9pzhj 2512 11 regimes regime NNS cord-005646-xhx9pzhj 2512 12 . . . cord-005646-xhx9pzhj 2513 1 Albano Albano NNP cord-005646-xhx9pzhj 2513 2 Communication Communication NNP cord-005646-xhx9pzhj 2513 3 is be VBZ cord-005646-xhx9pzhj 2513 4 an an DT cord-005646-xhx9pzhj 2513 5 important important JJ cord-005646-xhx9pzhj 2513 6 aspect aspect NN cord-005646-xhx9pzhj 2513 7 of of IN cord-005646-xhx9pzhj 2513 8 human human JJ cord-005646-xhx9pzhj 2513 9 development development NN cord-005646-xhx9pzhj 2513 10 and and CC cord-005646-xhx9pzhj 2513 11 existence existence NN cord-005646-xhx9pzhj 2513 12 , , , cord-005646-xhx9pzhj 2513 13 and and CC cord-005646-xhx9pzhj 2513 14 an an DT cord-005646-xhx9pzhj 2513 15 inability inability NN cord-005646-xhx9pzhj 2513 16 to to TO cord-005646-xhx9pzhj 2513 17 vocalise vocalise VB cord-005646-xhx9pzhj 2513 18 can can MD cord-005646-xhx9pzhj 2513 19 be be VB cord-005646-xhx9pzhj 2513 20 a a DT cord-005646-xhx9pzhj 2513 21 problem problem NN cord-005646-xhx9pzhj 2513 22 in in IN cord-005646-xhx9pzhj 2513 23 ventilatordependent ventilatordependent NN cord-005646-xhx9pzhj 2513 24 patients patient NNS cord-005646-xhx9pzhj 2513 25 . . . cord-005646-xhx9pzhj 2514 1 We -PRON- PRP cord-005646-xhx9pzhj 2514 2 present present VBP cord-005646-xhx9pzhj 2514 3 our -PRON- PRP$ cord-005646-xhx9pzhj 2514 4 experience experience NN cord-005646-xhx9pzhj 2514 5 with with IN cord-005646-xhx9pzhj 2514 6 speaking speak VBG cord-005646-xhx9pzhj 2514 7 aids aids NNP cord-005646-xhx9pzhj 2514 8 as as IN cord-005646-xhx9pzhj 2514 9 a a DT cord-005646-xhx9pzhj 2514 10 means means NN cord-005646-xhx9pzhj 2514 11 of of IN cord-005646-xhx9pzhj 2514 12 enhancing enhance VBG cord-005646-xhx9pzhj 2514 13 verbal verbal JJ cord-005646-xhx9pzhj 2514 14 communication communication NN cord-005646-xhx9pzhj 2514 15 in in IN cord-005646-xhx9pzhj 2514 16 four four CD cord-005646-xhx9pzhj 2514 17 ventilatordependent ventilatordependent NN cord-005646-xhx9pzhj 2514 18 children child NNS cord-005646-xhx9pzhj 2514 19 in in IN cord-005646-xhx9pzhj 2514 20 our -PRON- PRP$ cord-005646-xhx9pzhj 2514 21 Paediatric Paediatric NNP cord-005646-xhx9pzhj 2514 22 Intensive Intensive NNP cord-005646-xhx9pzhj 2514 23 Care Care NNP cord-005646-xhx9pzhj 2514 24 Unit Unit NNP cord-005646-xhx9pzhj 2514 25 . . . cord-005646-xhx9pzhj 2515 1 The the DT cord-005646-xhx9pzhj 2515 2 age age NN cord-005646-xhx9pzhj 2515 3 of of IN cord-005646-xhx9pzhj 2515 4 the the DT cord-005646-xhx9pzhj 2515 5 children child NNS cord-005646-xhx9pzhj 2515 6 ranged range VBD cord-005646-xhx9pzhj 2515 7 from from IN cord-005646-xhx9pzhj 2515 8 7 7 CD cord-005646-xhx9pzhj 2515 9 months month NNS cord-005646-xhx9pzhj 2515 10 to to IN cord-005646-xhx9pzhj 2515 11 5 5 CD cord-005646-xhx9pzhj 2515 12 years year NNS cord-005646-xhx9pzhj 2515 13 , , , cord-005646-xhx9pzhj 2515 14 and and CC cord-005646-xhx9pzhj 2515 15 the the DT cord-005646-xhx9pzhj 2515 16 period period NN cord-005646-xhx9pzhj 2515 17 of of IN cord-005646-xhx9pzhj 2515 18 ventilation ventilation NN cord-005646-xhx9pzhj 2515 19 ranged range VBD cord-005646-xhx9pzhj 2515 20 from from IN cord-005646-xhx9pzhj 2515 21 3 3 CD cord-005646-xhx9pzhj 2515 22 months month NNS cord-005646-xhx9pzhj 2515 23 to to IN cord-005646-xhx9pzhj 2515 24 21 21 CD cord-005646-xhx9pzhj 2515 25 months month NNS cord-005646-xhx9pzhj 2515 26 via via IN cord-005646-xhx9pzhj 2515 27 a a DT cord-005646-xhx9pzhj 2515 28 tracheostnmy tracheostnmy NN cord-005646-xhx9pzhj 2515 29 . . . cord-005646-xhx9pzhj 2516 1 They -PRON- PRP cord-005646-xhx9pzhj 2516 2 require require VBP cord-005646-xhx9pzhj 2516 3 continuous continuous JJ cord-005646-xhx9pzhj 2516 4 flow flow NN cord-005646-xhx9pzhj 2516 5 generated generate VBD cord-005646-xhx9pzhj 2516 6 pressure pressure NN cord-005646-xhx9pzhj 2516 7 limited limit VBN cord-005646-xhx9pzhj 2516 8 or or CC cord-005646-xhx9pzhj 2516 9 control control NN cord-005646-xhx9pzhj 2516 10 ventilation ventilation NN cord-005646-xhx9pzhj 2516 11 at at IN cord-005646-xhx9pzhj 2516 12 rates rate NNS cord-005646-xhx9pzhj 2516 13 of of IN cord-005646-xhx9pzhj 2516 14 13 13 CD cord-005646-xhx9pzhj 2516 15 - - SYM cord-005646-xhx9pzhj 2516 16 20 20 CD cord-005646-xhx9pzhj 2516 17 bpm bpm NN cord-005646-xhx9pzhj 2516 18 . . . cord-005646-xhx9pzhj 2517 1 The the DT cord-005646-xhx9pzhj 2517 2 reasons reason NNS cord-005646-xhx9pzhj 2517 3 for for IN cord-005646-xhx9pzhj 2517 4 ventilation ventilation NN cord-005646-xhx9pzhj 2517 5 include include VBP cord-005646-xhx9pzhj 2517 6 tetraptegia tetraptegia NN cord-005646-xhx9pzhj 2517 7 following follow VBG cord-005646-xhx9pzhj 2517 8 a a DT cord-005646-xhx9pzhj 2517 9 shrapnel shrapnel NN cord-005646-xhx9pzhj 2517 10 injury injury NN cord-005646-xhx9pzhj 2517 11 ; ; : cord-005646-xhx9pzhj 2517 12 tetraplegia tetraplegia NN cord-005646-xhx9pzhj 2517 13 following follow VBG cord-005646-xhx9pzhj 2517 14 congenital congenital JJ cord-005646-xhx9pzhj 2517 15 cervical cervical JJ cord-005646-xhx9pzhj 2517 16 spine spine NN cord-005646-xhx9pzhj 2517 17 damage damage NN cord-005646-xhx9pzhj 2517 18 ; ; : cord-005646-xhx9pzhj 2517 19 tetraplegia tetraplegia NNP cord-005646-xhx9pzhj 2517 20 following follow VBG cord-005646-xhx9pzhj 2517 21 atlanto atlanto NNP cord-005646-xhx9pzhj 2517 22 - - HYPH cord-005646-xhx9pzhj 2517 23 axial axial NN cord-005646-xhx9pzhj 2517 24 subluxation subluxation NN cord-005646-xhx9pzhj 2517 25 ; ; , cord-005646-xhx9pzhj 2517 26 and and CC cord-005646-xhx9pzhj 2517 27 critical critical JJ cord-005646-xhx9pzhj 2517 28 illness illness NN cord-005646-xhx9pzhj 2517 29 polyneuropathy polyneuropathy NN cord-005646-xhx9pzhj 2517 30 following follow VBG cord-005646-xhx9pzhj 2517 31 adult adult NN cord-005646-xhx9pzhj 2517 32 respiratory respiratory JJ cord-005646-xhx9pzhj 2517 33 distress distress NN cord-005646-xhx9pzhj 2517 34 syndrome syndrome NN cord-005646-xhx9pzhj 2517 35 from from IN cord-005646-xhx9pzhj 2517 36 prolonged prolong VBN cord-005646-xhx9pzhj 2517 37 ventilation ventilation NN cord-005646-xhx9pzhj 2517 38 for for IN cord-005646-xhx9pzhj 2517 39 a a DT cord-005646-xhx9pzhj 2517 40 severe severe JJ cord-005646-xhx9pzhj 2517 41 head head NN cord-005646-xhx9pzhj 2517 42 injury injury NN cord-005646-xhx9pzhj 2517 43 . . . cord-005646-xhx9pzhj 2518 1 The the DT cord-005646-xhx9pzhj 2518 2 first first JJ cord-005646-xhx9pzhj 2518 3 three three CD cord-005646-xhx9pzhj 2518 4 patients patient NNS cord-005646-xhx9pzhj 2518 5 have have VBP cord-005646-xhx9pzhj 2518 6 Passy Passy NNP cord-005646-xhx9pzhj 2518 7 - - HYPH cord-005646-xhx9pzhj 2518 8 Mnir Mnir NNP cord-005646-xhx9pzhj 2518 9 one one CD cord-005646-xhx9pzhj 2518 10 - - HYPH cord-005646-xhx9pzhj 2518 11 way way NN cord-005646-xhx9pzhj 2518 12 speaking speak VBG cord-005646-xhx9pzhj 2518 13 valves valve NNS cord-005646-xhx9pzhj 2518 14 and and CC cord-005646-xhx9pzhj 2518 15 the the DT cord-005646-xhx9pzhj 2518 16 final final JJ cord-005646-xhx9pzhj 2518 17 patient patient NN cord-005646-xhx9pzhj 2518 18 has have VBZ cord-005646-xhx9pzhj 2518 19 a a DT cord-005646-xhx9pzhj 2518 20 Bivona Bivona NNP cord-005646-xhx9pzhj 2518 21 foam foam NN cord-005646-xhx9pzhj 2518 22 cuffed cuff VBN cord-005646-xhx9pzhj 2518 23 tmcheostomy tmcheostomy NN cord-005646-xhx9pzhj 2518 24 tube tube NN cord-005646-xhx9pzhj 2518 25 with with IN cord-005646-xhx9pzhj 2518 26 a a DT cord-005646-xhx9pzhj 2518 27 talk talk NN cord-005646-xhx9pzhj 2518 28 attachment attachment NN cord-005646-xhx9pzhj 2518 29 in in IN cord-005646-xhx9pzhj 2518 30 view view NN cord-005646-xhx9pzhj 2518 31 of of IN cord-005646-xhx9pzhj 2518 32 recurrent recurrent JJ cord-005646-xhx9pzhj 2518 33 aspiration aspiration NN cord-005646-xhx9pzhj 2518 34 . . . cord-005646-xhx9pzhj 2519 1 An an DT cord-005646-xhx9pzhj 2519 2 improvement improvement NN cord-005646-xhx9pzhj 2519 3 in in IN cord-005646-xhx9pzhj 2519 4 quaIity quaiity NN cord-005646-xhx9pzhj 2519 5 of of IN cord-005646-xhx9pzhj 2519 6 speech speech NN cord-005646-xhx9pzhj 2519 7 has have VBZ cord-005646-xhx9pzhj 2519 8 been be VBN cord-005646-xhx9pzhj 2519 9 shown show VBN cord-005646-xhx9pzhj 2519 10 by by IN cord-005646-xhx9pzhj 2519 11 independent independent JJ cord-005646-xhx9pzhj 2519 12 assessment assessment NN cord-005646-xhx9pzhj 2519 13 . . . cord-005646-xhx9pzhj 2520 1 We -PRON- PRP cord-005646-xhx9pzhj 2520 2 will will MD cord-005646-xhx9pzhj 2520 3 review review VB cord-005646-xhx9pzhj 2520 4 the the DT cord-005646-xhx9pzhj 2520 5 present present JJ cord-005646-xhx9pzhj 2520 6 literature literature NN cord-005646-xhx9pzhj 2520 7 on on IN cord-005646-xhx9pzhj 2520 8 this this DT cord-005646-xhx9pzhj 2520 9 subject subject NN cord-005646-xhx9pzhj 2520 10 and and CC cord-005646-xhx9pzhj 2520 11 discuss discuss VB cord-005646-xhx9pzhj 2520 12 the the DT cord-005646-xhx9pzhj 2520 13 advantages advantage NNS cord-005646-xhx9pzhj 2520 14 and and CC cord-005646-xhx9pzhj 2520 15 disadvantages disadvantage NNS cord-005646-xhx9pzhj 2520 16 of of IN cord-005646-xhx9pzhj 2520 17 these these DT cord-005646-xhx9pzhj 2520 18 two two CD cord-005646-xhx9pzhj 2520 19 types type NNS cord-005646-xhx9pzhj 2520 20 of of IN cord-005646-xhx9pzhj 2520 21 speaking speak VBG cord-005646-xhx9pzhj 2520 22 aids aids NNP cord-005646-xhx9pzhj 2520 23 in in IN cord-005646-xhx9pzhj 2520 24 the the DT cord-005646-xhx9pzhj 2520 25 light light NN cord-005646-xhx9pzhj 2520 26 of of IN cord-005646-xhx9pzhj 2520 27 our -PRON- PRP$ cord-005646-xhx9pzhj 2520 28 experience experience NN cord-005646-xhx9pzhj 2520 29 . . . cord-005646-xhx9pzhj 2521 1 The the DT cord-005646-xhx9pzhj 2521 2 prognosis prognosis NN cord-005646-xhx9pzhj 2521 3 of of IN cord-005646-xhx9pzhj 2521 4 antenatally antenatally RB cord-005646-xhx9pzhj 2521 5 diagnosed diagnose VBN cord-005646-xhx9pzhj 2521 6 CDH CDH NNP cord-005646-xhx9pzhj 2521 7 is be VBZ cord-005646-xhx9pzhj 2521 8 closely closely RB cord-005646-xhx9pzhj 2521 9 related related JJ cord-005646-xhx9pzhj 2521 10 to to IN cord-005646-xhx9pzhj 2521 11 the the DT cord-005646-xhx9pzhj 2521 12 degree degree NN cord-005646-xhx9pzhj 2521 13 of of IN cord-005646-xhx9pzhj 2521 14 PH PH NNP cord-005646-xhx9pzhj 2521 15 . . . cord-005646-xhx9pzhj 2522 1 There there EX cord-005646-xhx9pzhj 2522 2 have have VBP cord-005646-xhx9pzhj 2522 3 been be VBN cord-005646-xhx9pzhj 2522 4 attempts attempt NNS cord-005646-xhx9pzhj 2522 5 to to TO cord-005646-xhx9pzhj 2522 6 correlate correlate VB cord-005646-xhx9pzhj 2522 7 antenatal antenatal JJ cord-005646-xhx9pzhj 2522 8 or or CC cord-005646-xhx9pzhj 2522 9 postnatal postnatal JJ cord-005646-xhx9pzhj 2522 10 criteria criterion NNS cord-005646-xhx9pzhj 2522 11 to to IN cord-005646-xhx9pzhj 2522 12 mortality mortality NN cord-005646-xhx9pzhj 2522 13 : : : cord-005646-xhx9pzhj 2522 14 none none NN cord-005646-xhx9pzhj 2522 15 have have VBP cord-005646-xhx9pzhj 2522 16 been be VBN cord-005646-xhx9pzhj 2522 17 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2522 18 to to TO cord-005646-xhx9pzhj 2522 19 be be VB cord-005646-xhx9pzhj 2522 20 predictive predictive JJ cord-005646-xhx9pzhj 2522 21 of of IN cord-005646-xhx9pzhj 2522 22 lethal lethal JJ cord-005646-xhx9pzhj 2522 23 PH PH NNP cord-005646-xhx9pzhj 2522 24 . . . cord-005646-xhx9pzhj 2523 1 The the DT cord-005646-xhx9pzhj 2523 2 aim aim NN cord-005646-xhx9pzhj 2523 3 of of IN cord-005646-xhx9pzhj 2523 4 this this DT cord-005646-xhx9pzhj 2523 5 retrospective retrospective JJ cord-005646-xhx9pzhj 2523 6 study study NN cord-005646-xhx9pzhj 2523 7 was be VBD cord-005646-xhx9pzhj 2523 8 to to TO cord-005646-xhx9pzhj 2523 9 determine determine VB cord-005646-xhx9pzhj 2523 10 whether whether IN cord-005646-xhx9pzhj 2523 11 antenatal antenatal JJ cord-005646-xhx9pzhj 2523 12 or or CC cord-005646-xhx9pzhj 2523 13 early early JJ cord-005646-xhx9pzhj 2523 14 postnatal postnatal JJ cord-005646-xhx9pzhj 2523 15 data datum NNS cord-005646-xhx9pzhj 2523 16 could could MD cord-005646-xhx9pzhj 2523 17 correlate correlate VB cord-005646-xhx9pzhj 2523 18 with with IN cord-005646-xhx9pzhj 2523 19 the the DT cord-005646-xhx9pzhj 2523 20 findings finding NNS cord-005646-xhx9pzhj 2523 21 of of IN cord-005646-xhx9pzhj 2523 22 post post JJ cord-005646-xhx9pzhj 2523 23 - - JJ cord-005646-xhx9pzhj 2523 24 mortem mortem JJ cord-005646-xhx9pzhj 2523 25 examinations examination NNS cord-005646-xhx9pzhj 2523 26 . . . cord-005646-xhx9pzhj 2524 1 Patients patient NNS cord-005646-xhx9pzhj 2524 2 and and CC cord-005646-xhx9pzhj 2524 3 methods method NNS cord-005646-xhx9pzhj 2524 4 : : : cord-005646-xhx9pzhj 2524 5 Between between IN cord-005646-xhx9pzhj 2524 6 July July NNP cord-005646-xhx9pzhj 2524 7 1990 1990 CD cord-005646-xhx9pzhj 2524 8 and and CC cord-005646-xhx9pzhj 2524 9 July July NNP cord-005646-xhx9pzhj 2524 10 1994 1994 CD cord-005646-xhx9pzhj 2524 11 , , , cord-005646-xhx9pzhj 2524 12 32 32 CD cord-005646-xhx9pzhj 2524 13 CDH CDH NNP cord-005646-xhx9pzhj 2524 14 patients patient NNS cord-005646-xhx9pzhj 2524 15 have have VBP cord-005646-xhx9pzhj 2524 16 been be VBN cord-005646-xhx9pzhj 2524 17 antenatally antenatally RB cord-005646-xhx9pzhj 2524 18 and and CC cord-005646-xhx9pzhj 2524 19 postnatally postnatally RB cord-005646-xhx9pzhj 2524 20 managed manage VBD cord-005646-xhx9pzhj 2524 21 at at IN cord-005646-xhx9pzhj 2524 22 our -PRON- PRP$ cord-005646-xhx9pzhj 2524 23 institution institution NN cord-005646-xhx9pzhj 2524 24 . . . cord-005646-xhx9pzhj 2525 1 Twentythree Twentythree NNP cord-005646-xhx9pzhj 2525 2 infants infant NNS cord-005646-xhx9pzhj 2525 3 underwent undergo VBD cord-005646-xhx9pzhj 2525 4 a a DT cord-005646-xhx9pzhj 2525 5 post post JJ cord-005646-xhx9pzhj 2525 6 - - JJ cord-005646-xhx9pzhj 2525 7 mortem mortem JJ cord-005646-xhx9pzhj 2525 8 examination examination NN cord-005646-xhx9pzhj 2525 9 . . . cord-005646-xhx9pzhj 2526 1 PH PH NNP cord-005646-xhx9pzhj 2526 2 was be VBD cord-005646-xhx9pzhj 2526 3 assessed assess VBN cord-005646-xhx9pzhj 2526 4 by by IN cord-005646-xhx9pzhj 2526 5 using use VBG cord-005646-xhx9pzhj 2526 6 the the DT cord-005646-xhx9pzhj 2526 7 lung lung NN cord-005646-xhx9pzhj 2526 8 weight weight NN cord-005646-xhx9pzhj 2526 9 to to IN cord-005646-xhx9pzhj 2526 10 body body NN cord-005646-xhx9pzhj 2526 11 weight weight NN cord-005646-xhx9pzhj 2526 12 ratio ratio NN cord-005646-xhx9pzhj 2526 13 ( ( -LRB- cord-005646-xhx9pzhj 2526 14 LW LW NNP cord-005646-xhx9pzhj 2526 15 / / SYM cord-005646-xhx9pzhj 2526 16 BW BW NNP cord-005646-xhx9pzhj 2526 17 ) ) -RRB- cord-005646-xhx9pzhj 2526 18 and and CC cord-005646-xhx9pzhj 2526 19 the the DT cord-005646-xhx9pzhj 2526 20 radial radial JJ cord-005646-xhx9pzhj 2526 21 alveolar alveolar NN cord-005646-xhx9pzhj 2526 22 count count NN cord-005646-xhx9pzhj 2526 23 ( ( -LRB- cord-005646-xhx9pzhj 2526 24 RAC RAC NNP cord-005646-xhx9pzhj 2526 25 ) ) -RRB- cord-005646-xhx9pzhj 2526 26 . . . cord-005646-xhx9pzhj 2527 1 Antenatal Antenatal NNP cord-005646-xhx9pzhj 2527 2 results result VBZ cord-005646-xhx9pzhj 2527 3 : : : cord-005646-xhx9pzhj 2527 4 CDH CDH NNP cord-005646-xhx9pzhj 2527 5 diagnosis diagnosis NN cord-005646-xhx9pzhj 2527 6 was be VBD cord-005646-xhx9pzhj 2527 7 made make VBN cord-005646-xhx9pzhj 2527 8 at at IN cord-005646-xhx9pzhj 2527 9 24 24 CD cord-005646-xhx9pzhj 2527 10 weeks week NNS cord-005646-xhx9pzhj 2527 11 of of IN cord-005646-xhx9pzhj 2527 12 gestation gestation NN cord-005646-xhx9pzhj 2527 13 ( ( -LRB- cord-005646-xhx9pzhj 2527 14 wg wg NNP cord-005646-xhx9pzhj 2527 15 ) ) -RRB- cord-005646-xhx9pzhj 2527 16 ( ( -LRB- cord-005646-xhx9pzhj 2527 17 15 15 CD cord-005646-xhx9pzhj 2527 18 - - SYM cord-005646-xhx9pzhj 2527 19 37 37 CD cord-005646-xhx9pzhj 2527 20 ) ) -RRB- cord-005646-xhx9pzhj 2527 21 . . . cord-005646-xhx9pzhj 2528 1 Twenty twenty CD cord-005646-xhx9pzhj 2528 2 - - HYPH cord-005646-xhx9pzhj 2528 3 eight eight CD cord-005646-xhx9pzhj 2528 4 patients patient NNS cord-005646-xhx9pzhj 2528 5 had have VBD cord-005646-xhx9pzhj 2528 6 a a DT cord-005646-xhx9pzhj 2528 7 left left JJ cord-005646-xhx9pzhj 2528 8 sided sided JJ cord-005646-xhx9pzhj 2528 9 CDH CDH NNP cord-005646-xhx9pzhj 2528 10 , , , cord-005646-xhx9pzhj 2528 11 3 3 CD cord-005646-xhx9pzhj 2528 12 had have VBD cord-005646-xhx9pzhj 2528 13 a a DT cord-005646-xhx9pzhj 2528 14 right right JJ cord-005646-xhx9pzhj 2528 15 sided sided JJ cord-005646-xhx9pzhj 2528 16 CDH CDH NNP cord-005646-xhx9pzhj 2528 17 , , , cord-005646-xhx9pzhj 2528 18 and and CC cord-005646-xhx9pzhj 2528 19 one one CD cord-005646-xhx9pzhj 2528 20 had have VBD cord-005646-xhx9pzhj 2528 21 a a DT cord-005646-xhx9pzhj 2528 22 bilateral bilateral JJ cord-005646-xhx9pzhj 2528 23 CDH cdh NN cord-005646-xhx9pzhj 2528 24 . . . cord-005646-xhx9pzhj 2529 1 Herniated herniated JJ cord-005646-xhx9pzhj 2529 2 organs organ NNS cord-005646-xhx9pzhj 2529 3 were be VBD cord-005646-xhx9pzhj 2529 4 stomach stomach NN cord-005646-xhx9pzhj 2530 1 None none NN cord-005646-xhx9pzhj 2530 2 ( ( -LRB- cord-005646-xhx9pzhj 2530 3 n=21 n=21 NNP cord-005646-xhx9pzhj 2530 4 ) ) -RRB- cord-005646-xhx9pzhj 2530 5 , , , cord-005646-xhx9pzhj 2530 6 or or CC cord-005646-xhx9pzhj 2530 7 liver liver NN cord-005646-xhx9pzhj 2530 8 alone alone RB cord-005646-xhx9pzhj 2530 9 ( ( -LRB- cord-005646-xhx9pzhj 2530 10 n=4 n=4 NNP cord-005646-xhx9pzhj 2530 11 ) ) -RRB- cord-005646-xhx9pzhj 2530 12 , , , cord-005646-xhx9pzhj 2530 13 or or CC cord-005646-xhx9pzhj 2530 14 both both DT cord-005646-xhx9pzhj 2530 15 stomach stomach NN cord-005646-xhx9pzhj 2530 16 and and CC cord-005646-xhx9pzhj 2530 17 liver liver NN cord-005646-xhx9pzhj 2531 1 ( ( -LRB- cord-005646-xhx9pzhj 2531 2 n=5 n=5 JJ cord-005646-xhx9pzhj 2532 1 The the DT cord-005646-xhx9pzhj 2532 2 patient patient NN cord-005646-xhx9pzhj 2532 3 was be VBD cord-005646-xhx9pzhj 2532 4 a a DT cord-005646-xhx9pzhj 2532 5 3-yenr 3-yenr CD cord-005646-xhx9pzhj 2532 6 - - HYPH cord-005646-xhx9pzhj 2532 7 old old JJ cord-005646-xhx9pzhj 2532 8 girl girl NN cord-005646-xhx9pzhj 2532 9 with with IN cord-005646-xhx9pzhj 2532 10 chronic chronic JJ cord-005646-xhx9pzhj 2532 11 renal renal JJ cord-005646-xhx9pzhj 2532 12 insufficiency insufficiency NN cord-005646-xhx9pzhj 2532 13 see~ see~ CD cord-005646-xhx9pzhj 2532 14 to to IN cord-005646-xhx9pzhj 2532 15 renal renal JJ cord-005646-xhx9pzhj 2532 16 dysptasm dysptasm NN cord-005646-xhx9pzhj 2532 17 , , , cord-005646-xhx9pzhj 2532 18 Two two CD cord-005646-xhx9pzhj 2532 19 months month NNS cord-005646-xhx9pzhj 2532 20 before before IN cord-005646-xhx9pzhj 2532 21 admission admission NN cord-005646-xhx9pzhj 2532 22 a a DT cord-005646-xhx9pzhj 2532 23 kidney kidney NN cord-005646-xhx9pzhj 2532 24 trar trar NNP cord-005646-xhx9pzhj 2532 25 ~ ~ NFP cord-005646-xhx9pzhj 2532 26 ptant ptant NNP cord-005646-xhx9pzhj 2532 27 was be VBD cord-005646-xhx9pzhj 2532 28 performed perform VBN cord-005646-xhx9pzhj 2532 29 . . . cord-005646-xhx9pzhj 2533 1 One one CD cord-005646-xhx9pzhj 2533 2 morah morah NN cord-005646-xhx9pzhj 2533 3 later later RBR cord-005646-xhx9pzhj 2533 4 she -PRON- PRP cord-005646-xhx9pzhj 2533 5 showed show VBD cord-005646-xhx9pzhj 2533 6 acute acute JJ cord-005646-xhx9pzhj 2533 7 graft graft NN cord-005646-xhx9pzhj 2533 8 rejection rejection NN cord-005646-xhx9pzhj 2533 9 with with IN cord-005646-xhx9pzhj 2533 10 serum serum NN cord-005646-xhx9pzhj 2533 11 ereafinine ereafinine NN cord-005646-xhx9pzhj 2533 12 ( ( -LRB- cord-005646-xhx9pzhj 2533 13 Cr cr NN cord-005646-xhx9pzhj 2533 14 ) ) -RRB- cord-005646-xhx9pzhj 2533 15 level level NN cord-005646-xhx9pzhj 2533 16 of of IN cord-005646-xhx9pzhj 2533 17 0.7 0.7 CD cord-005646-xhx9pzhj 2533 18 mg% mg% CD cord-005646-xhx9pzhj 2533 19 . . . cord-005646-xhx9pzhj 2534 1 The the DT cord-005646-xhx9pzhj 2534 2 rejection rejection NN cord-005646-xhx9pzhj 2534 3 was be VBD cord-005646-xhx9pzhj 2534 4 unreslxmsive unreslxmsive JJ cord-005646-xhx9pzhj 2534 5 to to IN cord-005646-xhx9pzhj 2534 6 an an DT cord-005646-xhx9pzhj 2534 7 increased increase VBN cord-005646-xhx9pzhj 2534 8 steroid steroid NN cord-005646-xhx9pzhj 2534 9 dosage dosage NN cord-005646-xhx9pzhj 2534 10 , , , cord-005646-xhx9pzhj 2534 11 and and CC cord-005646-xhx9pzhj 2534 12 OKT3 OKT3 NNP cord-005646-xhx9pzhj 2534 13 was be VBD cord-005646-xhx9pzhj 2534 14 begun begin VBN cord-005646-xhx9pzhj 2534 15 with with IN cord-005646-xhx9pzhj 2534 16 resolution resolution NN cord-005646-xhx9pzhj 2534 17 of of IN cord-005646-xhx9pzhj 2534 18 the the DT cord-005646-xhx9pzhj 2534 19 rejection rejection NN cord-005646-xhx9pzhj 2534 20 . . . cord-005646-xhx9pzhj 2535 1 One one CD cord-005646-xhx9pzhj 2535 2 week week NN cord-005646-xhx9pzhj 2535 3 aRer aRer NNP cord-005646-xhx9pzhj 2535 4 , , , cord-005646-xhx9pzhj 2535 5 new new JJ cord-005646-xhx9pzhj 2535 6 rejection rejection NN cord-005646-xhx9pzhj 2535 7 episode episode NN cord-005646-xhx9pzhj 2535 8 was be VBD cord-005646-xhx9pzhj 2535 9 seen see VBN cord-005646-xhx9pzhj 2535 10 marestxmsive marestxmsive NNP cord-005646-xhx9pzhj 2535 11 to to IN cord-005646-xhx9pzhj 2535 12 an an DT cord-005646-xhx9pzhj 2535 13 increased increase VBN cord-005646-xhx9pzhj 2535 14 steroid steroid NN cord-005646-xhx9pzhj 2535 15 dosage dosage NN cord-005646-xhx9pzhj 2535 16 , , , cord-005646-xhx9pzhj 2535 17 and and CC cord-005646-xhx9pzhj 2535 18 transp~ transp~ NNP cord-005646-xhx9pzhj 2536 1 ~s ~s NNP cord-005646-xhx9pzhj 2536 2 performed perform VBD cord-005646-xhx9pzhj 2536 3 five five CD cord-005646-xhx9pzhj 2536 4 days day NNS cord-005646-xhx9pzhj 2536 5 before before IN cord-005646-xhx9pzhj 2536 6 admission admission NN cord-005646-xhx9pzhj 2536 7 to to IN cord-005646-xhx9pzhj 2536 8 our -PRON- PRP$ cord-005646-xhx9pzhj 2536 9 PtC. PtC. NNP cord-005646-xhx9pzhj 2536 10 Hemedialysis Hemedialysis NNP cord-005646-xhx9pzhj 2536 11 and and CC cord-005646-xhx9pzhj 2536 12 Peritoneal Peritoneal NNP cord-005646-xhx9pzhj 2536 13 dialysis dialysis NN cord-005646-xhx9pzhj 2536 14 ( ( -LRB- cord-005646-xhx9pzhj 2536 15 P.D. P.D. NNP cord-005646-xhx9pzhj 2536 16 ) ) -RRB- cord-005646-xhx9pzhj 2536 17 each each DT cord-005646-xhx9pzhj 2536 18 other other JJ cord-005646-xhx9pzhj 2536 19 day day NN cord-005646-xhx9pzhj 2536 20 , , , cord-005646-xhx9pzhj 2536 21 was be VBD cord-005646-xhx9pzhj 2536 22 indicated indicate VBN cord-005646-xhx9pzhj 2536 23 ( ( -LRB- cord-005646-xhx9pzhj 2536 24 G.R.F. G.R.F. NNP cord-005646-xhx9pzhj 2536 25 < < XX cord-005646-xhx9pzhj 2536 26 10 10 CD cord-005646-xhx9pzhj 2536 27 ml ml NN cord-005646-xhx9pzhj 2536 28 / / SYM cord-005646-xhx9pzhj 2536 29 rnin rnin NN cord-005646-xhx9pzhj 2536 30 ) ) -RRB- cord-005646-xhx9pzhj 2536 31 . . . cord-005646-xhx9pzhj 2537 1 Four four CD cord-005646-xhx9pzhj 2537 2 days day NNS cord-005646-xhx9pzhj 2537 3 before before IN cord-005646-xhx9pzhj 2537 4 admission admission NN cord-005646-xhx9pzhj 2537 5 T T NNP cord-005646-xhx9pzhj 2537 6 ~ ~ NFP cord-005646-xhx9pzhj 2537 7 rose rise VBD cord-005646-xhx9pzhj 2537 8 to to IN cord-005646-xhx9pzhj 2537 9 38 38 CD cord-005646-xhx9pzhj 2537 10 ° ° NN cord-005646-xhx9pzhj 2537 11 C c NN cord-005646-xhx9pzhj 2537 12 . . . cord-005646-xhx9pzhj 2538 1 " " `` cord-005646-xhx9pzhj 2538 2 lhe lhe JJ cord-005646-xhx9pzhj 2538 3 diagnosis diagnosis NN cord-005646-xhx9pzhj 2538 4 of of IN cord-005646-xhx9pzhj 2538 5 opporttmistic opporttmistic NNP cord-005646-xhx9pzhj 2538 6 pneumoma pneumoma NNP cord-005646-xhx9pzhj 2538 7 was be VBD cord-005646-xhx9pzhj 2538 8 made make VBN cord-005646-xhx9pzhj 2538 9 on on IN cord-005646-xhx9pzhj 2538 10 the the DT cord-005646-xhx9pzhj 2538 11 basis basis NN cord-005646-xhx9pzhj 2538 12 of of IN cord-005646-xhx9pzhj 2538 13 tach3,pr',e~ tach3,pr',e~ NN cord-005646-xhx9pzhj 2538 14 hypoxi~ hypoxi~ NNP cord-005646-xhx9pzhj 2538 15 and and CC cord-005646-xhx9pzhj 2538 16 diffuse diffuse VB cord-005646-xhx9pzhj 2538 17 interstitial interstitial JJ cord-005646-xhx9pzhj 2538 18 infiltrates infiltrate NNS cord-005646-xhx9pzhj 2538 19 . . . cord-005646-xhx9pzhj 2539 1 Senma Senma NNP cord-005646-xhx9pzhj 2539 2 ~ ~ NFP cord-005646-xhx9pzhj 2539 3 was be VBD cord-005646-xhx9pzhj 2539 4 positive positive JJ cord-005646-xhx9pzhj 2539 5 for for IN cord-005646-xhx9pzhj 2539 6 cytomegaloviras cytomegaloviras NNP cord-005646-xhx9pzhj 2539 7 ( ( -LRB- cord-005646-xhx9pzhj 2539 8 CMV CMV NNP cord-005646-xhx9pzhj 2539 9 ) ) -RRB- cord-005646-xhx9pzhj 2539 10 , , , cord-005646-xhx9pzhj 2539 11 and and CC cord-005646-xhx9pzhj 2539 12 stool stool NN cord-005646-xhx9pzhj 2539 13 culture culture NN cord-005646-xhx9pzhj 2539 14 for for IN cord-005646-xhx9pzhj 2539 15 C C NNP cord-005646-xhx9pzhj 2539 16 ALbicans ALbicans NNPS cord-005646-xhx9pzhj 2539 17 . . . cord-005646-xhx9pzhj 2540 1 Pentamidine Pentamidine NNP cord-005646-xhx9pzhj 2540 2 , , , cord-005646-xhx9pzhj 2540 3 ganciclovir ganciclovir FW cord-005646-xhx9pzhj 2540 4 ( ( -LRB- cord-005646-xhx9pzhj 2540 5 DHPG DHPG NNP cord-005646-xhx9pzhj 2540 6 ) ) -RRB- cord-005646-xhx9pzhj 2540 7 , , , cord-005646-xhx9pzhj 2540 8 arai arai NNP cord-005646-xhx9pzhj 2540 9 - - HYPH cord-005646-xhx9pzhj 2540 10 CMV CMV NNP cord-005646-xhx9pzhj 2540 11 gamma gamma NN cord-005646-xhx9pzhj 2540 12 globulin globulin NN cord-005646-xhx9pzhj 2540 13 , , , cord-005646-xhx9pzhj 2540 14 eritromicine eritromicine NN cord-005646-xhx9pzhj 2540 15 and and CC cord-005646-xhx9pzhj 2540 16 amphotericin amphotericin NNS cord-005646-xhx9pzhj 2540 17 B B NNP cord-005646-xhx9pzhj 2540 18 was be VBD cord-005646-xhx9pzhj 2540 19 administered administer VBN cord-005646-xhx9pzhj 2540 20 . . . cord-005646-xhx9pzhj 2541 1 On on IN cord-005646-xhx9pzhj 2541 2 admission admission NN cord-005646-xhx9pzhj 2541 3 in in IN cord-005646-xhx9pzhj 2541 4 our -PRON- PRP$ cord-005646-xhx9pzhj 2541 5 PICU PICU NNP cord-005646-xhx9pzhj 2541 6 , , , cord-005646-xhx9pzhj 2541 7 trachea trachea NN cord-005646-xhx9pzhj 2541 8 was be VBD cord-005646-xhx9pzhj 2541 9 mmbated mmbate VBN cord-005646-xhx9pzhj 2541 10 , , , cord-005646-xhx9pzhj 2541 11 ( ( -LRB- cord-005646-xhx9pzhj 2541 12 A A NNP cord-005646-xhx9pzhj 2541 13 - - HYPH cord-005646-xhx9pzhj 2541 14 a a DT cord-005646-xhx9pzhj 2541 15 ) ) -RRB- cord-005646-xhx9pzhj 2541 16 O2 o2 NN cord-005646-xhx9pzhj 2541 17 gradient gradient NN cord-005646-xhx9pzhj 2541 18 was be VBD cord-005646-xhx9pzhj 2541 19 600 600 CD cord-005646-xhx9pzhj 2541 20 , , , cord-005646-xhx9pzhj 2541 21 PaOffFiO~ PaOffFiO~ NNP cord-005646-xhx9pzhj 2541 22 : : : cord-005646-xhx9pzhj 2541 23 65 65 CD cord-005646-xhx9pzhj 2542 1 , , , cord-005646-xhx9pzhj 2542 2 Lung Lung NNP cord-005646-xhx9pzhj 2542 3 Injury injury NN cord-005646-xhx9pzhj 2542 4 Score score NN cord-005646-xhx9pzhj 2542 5 > > XX cord-005646-xhx9pzhj 2543 1 3 3 CD cord-005646-xhx9pzhj 2543 2 with with IN cord-005646-xhx9pzhj 2543 3 PEEP peep NN cord-005646-xhx9pzhj 2543 4 level level NN cord-005646-xhx9pzhj 2543 5 of of IN cord-005646-xhx9pzhj 2543 6 8 8 CD cord-005646-xhx9pzhj 2543 7 cm cm NNS cord-005646-xhx9pzhj 2544 1 HzO. HzO. NNP cord-005646-xhx9pzhj 2545 1 She -PRON- PRP cord-005646-xhx9pzhj 2545 2 had have VBD cord-005646-xhx9pzhj 2545 3 normal normal JJ cord-005646-xhx9pzhj 2545 4 fiver fiver NN cord-005646-xhx9pzhj 2545 5 function function NN cord-005646-xhx9pzhj 2545 6 . . . cord-005646-xhx9pzhj 2546 1 During during IN cord-005646-xhx9pzhj 2546 2 te te NNP cord-005646-xhx9pzhj 2546 3 next next JJ cord-005646-xhx9pzhj 2546 4 days day NNS cord-005646-xhx9pzhj 2546 5 she -PRON- PRP cord-005646-xhx9pzhj 2546 6 had have VBD cord-005646-xhx9pzhj 2546 7 fever fever NN cord-005646-xhx9pzhj 2546 8 and and CC cord-005646-xhx9pzhj 2546 9 developed develop VBD cord-005646-xhx9pzhj 2546 10 ARDS ARDS NNP cord-005646-xhx9pzhj 2546 11 . . . cord-005646-xhx9pzhj 2547 1 BAL BAL NNP cord-005646-xhx9pzhj 2547 2 was be VBD cord-005646-xhx9pzhj 2547 3 negative negative JJ cord-005646-xhx9pzhj 2547 4 . . . cord-005646-xhx9pzhj 2548 1 P.D. P.D. NNP cord-005646-xhx9pzhj 2548 2 was be VBD cord-005646-xhx9pzhj 2548 3 of of IN cord-005646-xhx9pzhj 2548 4 little little JJ cord-005646-xhx9pzhj 2548 5 efficiency efficiency NN cord-005646-xhx9pzhj 2548 6 . . . cord-005646-xhx9pzhj 2549 1 We -PRON- PRP cord-005646-xhx9pzhj 2549 2 adjusted adjust VBD cord-005646-xhx9pzhj 2549 3 pentanfdine pentanfdine NN cord-005646-xhx9pzhj 2549 4 , , , cord-005646-xhx9pzhj 2549 5 and and CC cord-005646-xhx9pzhj 2549 6 DHPG dhpg JJ cord-005646-xhx9pzhj 2549 7 doses dose NNS cord-005646-xhx9pzhj 2549 8 for for IN cord-005646-xhx9pzhj 2549 9 severe severe JJ cord-005646-xhx9pzhj 2549 10 renal renal JJ cord-005646-xhx9pzhj 2549 11 failure failure NN cord-005646-xhx9pzhj 2549 12 , , , cord-005646-xhx9pzhj 2549 13 with with IN cord-005646-xhx9pzhj 2549 14 supplements supplement NNS cord-005646-xhx9pzhj 2549 15 after after IN cord-005646-xhx9pzhj 2549 16 herO hero NN cord-005646-xhx9pzhj 2549 17 , , , cord-005646-xhx9pzhj 2549 18 sis sis NNP cord-005646-xhx9pzhj 2549 19 , , , cord-005646-xhx9pzhj 2549 20 and and CC cord-005646-xhx9pzhj 2549 21 at at IN cord-005646-xhx9pzhj 2549 22 ~ ~ NFP cord-005646-xhx9pzhj 2549 23 rP.D rp.d VB cord-005646-xhx9pzhj 2549 24 .. .. . cord-005646-xhx9pzhj 2550 1 During during IN cord-005646-xhx9pzhj 2550 2 ~ ~ NFP cord-005646-xhx9pzhj 2550 3 next next JJ cord-005646-xhx9pzhj 2550 4 days day NNS cord-005646-xhx9pzhj 2550 5 she -PRON- PRP cord-005646-xhx9pzhj 2550 6 was be VBD cord-005646-xhx9pzhj 2550 7 afebrile afebrile JJ cord-005646-xhx9pzhj 2550 8 , , , cord-005646-xhx9pzhj 2550 9 and and CC cord-005646-xhx9pzhj 2550 10 the the DT cord-005646-xhx9pzhj 2550 11 chest chest NN cord-005646-xhx9pzhj 2550 12 became become VBD cord-005646-xhx9pzhj 2550 13 radiologlcally radiologlcally RB cord-005646-xhx9pzhj 2550 14 normal normal JJ cord-005646-xhx9pzhj 2550 15 . . . cord-005646-xhx9pzhj 2551 1 After after IN cord-005646-xhx9pzhj 2551 2 ten ten CD cord-005646-xhx9pzhj 2551 3 days day NNS cord-005646-xhx9pzhj 2551 4 on on IN cord-005646-xhx9pzhj 2551 5 Menhani Menhani NNP cord-005646-xhx9pzhj 2551 6 ~ ~ NFP cord-005646-xhx9pzhj 2551 7 al al NNP cord-005646-xhx9pzhj 2551 8 Ventilation Ventilation NNP cord-005646-xhx9pzhj 2551 9 ( ( -LRB- cord-005646-xhx9pzhj 2551 10 MV MV NNP cord-005646-xhx9pzhj 2551 11 . . . cord-005646-xhx9pzhj 2551 12 ) ) -RRB- cord-005646-xhx9pzhj 2551 13 , , , cord-005646-xhx9pzhj 2551 14 the the DT cord-005646-xhx9pzhj 2551 15 patient patient NN cord-005646-xhx9pzhj 2551 16 was be VBD cord-005646-xhx9pzhj 2551 17 extubated extubate VBN cord-005646-xhx9pzhj 2551 18 . . . cord-005646-xhx9pzhj 2552 1 Cr cr NN cord-005646-xhx9pzhj 2552 2 . . NNP cord-005646-xhx9pzhj 2552 3 level level NN cord-005646-xhx9pzhj 2552 4 was be VBD cord-005646-xhx9pzhj 2552 5 3.2 3.2 CD cord-005646-xhx9pzhj 2552 6 rag% rag% NNS cord-005646-xhx9pzhj 2552 7 , , , cord-005646-xhx9pzhj 2552 8 ( ( -LRB- cord-005646-xhx9pzhj 2552 9 A a NN cord-005646-xhx9pzhj 2552 10 - - HYPH cord-005646-xhx9pzhj 2552 11 a a NN cord-005646-xhx9pzhj 2552 12 ) ) -RRB- cord-005646-xhx9pzhj 2552 13 Oz Oz NNP cord-005646-xhx9pzhj 2552 14 gradient gradient NN cord-005646-xhx9pzhj 2552 15 was be VBD cord-005646-xhx9pzhj 2552 16 20 20 CD cord-005646-xhx9pzhj 2552 17 , , , cord-005646-xhx9pzhj 2552 18 and and CC cord-005646-xhx9pzhj 2552 19 PaOyFiOz paoyfioz NN cord-005646-xhx9pzhj 2552 20 was be VBD cord-005646-xhx9pzhj 2552 21 375 375 CD cord-005646-xhx9pzhj 2552 22 , , , cord-005646-xhx9pzhj 2552 23 The the DT cord-005646-xhx9pzhj 2552 24 patiem patiem NN cord-005646-xhx9pzhj 2552 25 was be VBD cord-005646-xhx9pzhj 2552 26 discharged discharge VBN cord-005646-xhx9pzhj 2552 27 with with IN cord-005646-xhx9pzhj 2552 28 chronic chronic JJ cord-005646-xhx9pzhj 2552 29 ambulatory ambulatory JJ cord-005646-xhx9pzhj 2552 30 P.D. P.D. NNP cord-005646-xhx9pzhj 2552 31 DISCUSSION discussion NN cord-005646-xhx9pzhj 2552 32 : : : cord-005646-xhx9pzhj 2553 1 OPPORTUNISTIC opportunistic JJ cord-005646-xhx9pzhj 2553 2 PNEUMONIA pneumonia NN cord-005646-xhx9pzhj 2553 3 is be VBZ cord-005646-xhx9pzhj 2553 4 a a DT cord-005646-xhx9pzhj 2553 5 major major JJ cord-005646-xhx9pzhj 2553 6 complicalaou complicalaou NNS cord-005646-xhx9pzhj 2553 7 in in IN cord-005646-xhx9pzhj 2553 8 imm imm NNP cord-005646-xhx9pzhj 2553 9 ~ ~ NFP cord-005646-xhx9pzhj 2553 10 romised romise VBN cord-005646-xhx9pzhj 2553 11 children child NNS cord-005646-xhx9pzhj 2553 12 , , , cord-005646-xhx9pzhj 2553 13 specially specially RB cord-005646-xhx9pzhj 2553 14 after after IN cord-005646-xhx9pzhj 2553 15 kidney kidney NN cord-005646-xhx9pzhj 2553 16 tvansplaraafion tvansplaraafion NN cord-005646-xhx9pzhj 2553 17 . . . cord-005646-xhx9pzhj 2554 1 C C NNP cord-005646-xhx9pzhj 2554 2 M.V. M.V. NNP cord-005646-xhx9pzhj 2554 3 infection infection NN cord-005646-xhx9pzhj 2554 4 can can MD cord-005646-xhx9pzhj 2554 5 result result VB cord-005646-xhx9pzhj 2554 6 at at IN cord-005646-xhx9pzhj 2554 7 ~ ~ CD cord-005646-xhx9pzhj 2554 8 r r NNP cord-005646-xhx9pzhj 2554 9 OKT3 OKT3 NNP cord-005646-xhx9pzhj 2554 10 administration administration NN cord-005646-xhx9pzhj 2554 11 . . . cord-005646-xhx9pzhj 2555 1 In in IN cord-005646-xhx9pzhj 2555 2 the the DT cord-005646-xhx9pzhj 2555 3 treatment treatment NN cord-005646-xhx9pzhj 2555 4 DHIK DHIK NNP cord-005646-xhx9pzhj 2555 5 } } -RRB- cord-005646-xhx9pzhj 2555 6 dose dose NN cord-005646-xhx9pzhj 2555 7 muSt muSt MD cord-005646-xhx9pzhj 2555 8 be be VB cord-005646-xhx9pzhj 2555 9 adapted adapt VBN cord-005646-xhx9pzhj 2555 10 to to IN cord-005646-xhx9pzhj 2555 11 the the DT cord-005646-xhx9pzhj 2555 12 degree degree NN cord-005646-xhx9pzhj 2555 13 of of IN cord-005646-xhx9pzhj 2555 14 renal renal JJ cord-005646-xhx9pzhj 2555 15 insu insu NNS cord-005646-xhx9pzhj 2555 16 ~ ~ NFP cord-005646-xhx9pzhj 2555 17 cieney cieney NN cord-005646-xhx9pzhj 2555 18 , , , cord-005646-xhx9pzhj 2555 19 with with IN cord-005646-xhx9pzhj 2555 20 supplements supplement NNS cord-005646-xhx9pzhj 2555 21 after after IN cord-005646-xhx9pzhj 2555 22 hemedialysis hemedialysis NN cord-005646-xhx9pzhj 2555 23 , , , cord-005646-xhx9pzhj 2555 24 and and CC cord-005646-xhx9pzhj 2555 25 after after IN cord-005646-xhx9pzhj 2555 26 PD PD NNP cord-005646-xhx9pzhj 2555 27 . . . cord-005646-xhx9pzhj 2556 1 Pneu Pneu NNP cord-005646-xhx9pzhj 2556 2 ~ ~ NFP cord-005646-xhx9pzhj 2556 3 y y NN cord-005646-xhx9pzhj 2556 4 ~ ~ NFP cord-005646-xhx9pzhj 2556 5 tis tis NNP cord-005646-xhx9pzhj 2556 6 cann cann NNP cord-005646-xhx9pzhj 2556 7 # # NN cord-005646-xhx9pzhj 2556 8 tmeumov~ tmeumov~ NN cord-005646-xhx9pzhj 2556 9 is be VBZ cord-005646-xhx9pzhj 2556 10 ehemeterized ehemeterize VBN cord-005646-xhx9pzhj 2556 11 by by IN cord-005646-xhx9pzhj 2556 12 ventilafion ventilafion NN cord-005646-xhx9pzhj 2556 13 - - HYPH cord-005646-xhx9pzhj 2556 14 perfusion perfusion NN cord-005646-xhx9pzhj 2556 15 mistmaeh mistmaeh NNS cord-005646-xhx9pzhj 2556 16 , , , cord-005646-xhx9pzhj 2556 17 decreased decrease VBD cord-005646-xhx9pzhj 2556 18 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2556 19 compliance compliance NN cord-005646-xhx9pzhj 2556 20 , , , cord-005646-xhx9pzhj 2556 21 hypoxia hypoxia NN cord-005646-xhx9pzhj 2556 22 arld arld NN cord-005646-xhx9pzhj 2556 23 elevated elevate VBD cord-005646-xhx9pzhj 2556 24 ( ( -LRB- cord-005646-xhx9pzhj 2556 25 A a NN cord-005646-xhx9pzhj 2556 26 - - HYPH cord-005646-xhx9pzhj 2556 27 a a NN cord-005646-xhx9pzhj 2556 28 ) ) -RRB- cord-005646-xhx9pzhj 2556 29 Oz Oz NNP cord-005646-xhx9pzhj 2556 30 gradient gradient NN cord-005646-xhx9pzhj 2556 31 , , , cord-005646-xhx9pzhj 2556 32 with with IN cord-005646-xhx9pzhj 2556 33 diffuse diffuse JJ cord-005646-xhx9pzhj 2556 34 interstitial interstitial JJ cord-005646-xhx9pzhj 2556 35 infiltrates infiltrate NNS cord-005646-xhx9pzhj 2556 36 . . . cord-005646-xhx9pzhj 2557 1 In in IN cord-005646-xhx9pzhj 2557 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2557 3 ease ease NN cord-005646-xhx9pzhj 2557 4 BAL BAL NNP cord-005646-xhx9pzhj 2557 5 was be VBD cord-005646-xhx9pzhj 2557 6 negative negative JJ cord-005646-xhx9pzhj 2557 7 . . . cord-005646-xhx9pzhj 2558 1 Although although IN cord-005646-xhx9pzhj 2558 2 we -PRON- PRP cord-005646-xhx9pzhj 2558 3 did do VBD cord-005646-xhx9pzhj 2558 4 not not RB cord-005646-xhx9pzhj 2558 5 find find VB cord-005646-xhx9pzhj 2558 6 the the DT cord-005646-xhx9pzhj 2558 7 etiology etiology NN cord-005646-xhx9pzhj 2558 8 the the DT cord-005646-xhx9pzhj 2558 9 prevoclons prevoclon NNS cord-005646-xhx9pzhj 2558 10 eombh eombh NNP cord-005646-xhx9pzhj 2559 1 ~ation ~ation NNP cord-005646-xhx9pzhj 2559 2 of of IN cord-005646-xhx9pzhj 2559 3 arairmcrobiat arairmcrobiat NNP cord-005646-xhx9pzhj 2559 4 therapy therapy NN cord-005646-xhx9pzhj 2559 5 , , , cord-005646-xhx9pzhj 2559 6 along along IN cord-005646-xhx9pzhj 2559 7 with with IN cord-005646-xhx9pzhj 2559 8 M.V. M.V. NNP cord-005646-xhx9pzhj 2559 9 , , , cord-005646-xhx9pzhj 2559 10 and and CC cord-005646-xhx9pzhj 2559 11 supportive supportive JJ cord-005646-xhx9pzhj 2559 12 measures measure NNS cord-005646-xhx9pzhj 2559 13 were be VBD cord-005646-xhx9pzhj 2559 14 the the DT cord-005646-xhx9pzhj 2559 15 most most RBS cord-005646-xhx9pzhj 2559 16 effective effective JJ cord-005646-xhx9pzhj 2559 17 trealme~. trealme~. JJ cord-005646-xhx9pzhj 2559 18 CONCLUSION conclusion NN cord-005646-xhx9pzhj 2559 19 : : : cord-005646-xhx9pzhj 2559 20 1 1 LS cord-005646-xhx9pzhj 2559 21 ) ) -RRB- cord-005646-xhx9pzhj 2560 1 In in IN cord-005646-xhx9pzhj 2560 2 patients patient NNS cord-005646-xhx9pzhj 2560 3 with with IN cord-005646-xhx9pzhj 2560 4 severe severe JJ cord-005646-xhx9pzhj 2560 5 renal renal JJ cord-005646-xhx9pzhj 2560 6 failure failure NN cord-005646-xhx9pzhj 2560 7 and and CC cord-005646-xhx9pzhj 2560 8 life life NN cord-005646-xhx9pzhj 2560 9 - - HYPH cord-005646-xhx9pzhj 2560 10 threatening threaten VBG cord-005646-xhx9pzhj 2560 11 infections infection NNS cord-005646-xhx9pzhj 2560 12 , , , cord-005646-xhx9pzhj 2560 13 we -PRON- PRP cord-005646-xhx9pzhj 2560 14 must must MD cord-005646-xhx9pzhj 2560 15 co co VB cord-005646-xhx9pzhj 2560 16 ~ ~ NNP cord-005646-xhx9pzhj 2560 17 ider ider NNP cord-005646-xhx9pzhj 2560 18 drug drug NN cord-005646-xhx9pzhj 2560 19 adjuslments adjuslments NNP cord-005646-xhx9pzhj 2560 20 . . . cord-005646-xhx9pzhj 2561 1 2 2 LS cord-005646-xhx9pzhj 2561 2 ) ) -RRB- cord-005646-xhx9pzhj 2562 1 In in IN cord-005646-xhx9pzhj 2562 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2562 3 patient patient NN cord-005646-xhx9pzhj 2562 4 we -PRON- PRP cord-005646-xhx9pzhj 2562 5 gave give VBD cord-005646-xhx9pzhj 2562 6 DHPG dhpg JJ cord-005646-xhx9pzhj 2562 7 supplements supplement NNS cord-005646-xhx9pzhj 2562 8 at at IN cord-005646-xhx9pzhj 2562 9 ~ ~ CD cord-005646-xhx9pzhj 2562 10 r r NN cord-005646-xhx9pzhj 2562 11 PD PD NNP cord-005646-xhx9pzhj 2562 12 . . . cord-005646-xhx9pzhj 2563 1 with with IN cord-005646-xhx9pzhj 2563 2 excett excett NNP cord-005646-xhx9pzhj 2563 3 ~ ~ NFP cord-005646-xhx9pzhj 2563 4 at at IN cord-005646-xhx9pzhj 2563 5 results result NNS cord-005646-xhx9pzhj 2563 6 , , , cord-005646-xhx9pzhj 2563 7 although although IN cord-005646-xhx9pzhj 2563 8 P.D. P.D. NNP cord-005646-xhx9pzhj 2563 9 was be VBD cord-005646-xhx9pzhj 2563 10 of of IN cord-005646-xhx9pzhj 2563 11 little little JJ cord-005646-xhx9pzhj 2563 12 effiele~. effiele~. NN cord-005646-xhx9pzhj 2563 13 _SP cord-005646-xhx9pzhj 2563 14 Introduction introduction NN cord-005646-xhx9pzhj 2563 15 : : : cord-005646-xhx9pzhj 2563 16 Endotracheal endotracheal JJ cord-005646-xhx9pzhj 2563 17 intubation intubation NN cord-005646-xhx9pzhj 2563 18 and and CC cord-005646-xhx9pzhj 2563 19 mechanical mechanical JJ cord-005646-xhx9pzhj 2563 20 ventilation ventilation NN cord-005646-xhx9pzhj 2563 21 have have VBP cord-005646-xhx9pzhj 2563 22 become become VBN cord-005646-xhx9pzhj 2563 23 an an DT cord-005646-xhx9pzhj 2563 24 important important JJ cord-005646-xhx9pzhj 2563 25 treatmem treatmem NN cord-005646-xhx9pzhj 2563 26 for for IN cord-005646-xhx9pzhj 2563 27 many many JJ cord-005646-xhx9pzhj 2563 28 diseases disease NNS cord-005646-xhx9pzhj 2563 29 accompanied accompany VBN cord-005646-xhx9pzhj 2563 30 by by IN cord-005646-xhx9pzhj 2563 31 respiratory respiratory JJ cord-005646-xhx9pzhj 2563 32 failure failure NN cord-005646-xhx9pzhj 2563 33 . . . cord-005646-xhx9pzhj 2564 1 With with IN cord-005646-xhx9pzhj 2564 2 the the DT cord-005646-xhx9pzhj 2564 3 frequent frequent JJ cord-005646-xhx9pzhj 2564 4 use use NN cord-005646-xhx9pzhj 2564 5 of of IN cord-005646-xhx9pzhj 2564 6 this this DT cord-005646-xhx9pzhj 2564 7 treatment treatment NN cord-005646-xhx9pzhj 2564 8 modality modality NN cord-005646-xhx9pzhj 2564 9 , , , cord-005646-xhx9pzhj 2564 10 an an DT cord-005646-xhx9pzhj 2564 11 increasing increase VBG cord-005646-xhx9pzhj 2564 12 number number NN cord-005646-xhx9pzhj 2564 13 of of IN cord-005646-xhx9pzhj 2564 14 complications complication NNS cord-005646-xhx9pzhj 2564 15 associated associate VBN cord-005646-xhx9pzhj 2564 16 with with IN cord-005646-xhx9pzhj 2564 17 endotracheal endotracheal JJ cord-005646-xhx9pzhj 2564 18 intubation intubation NN cord-005646-xhx9pzhj 2564 19 have have VBP cord-005646-xhx9pzhj 2564 20 gained gain VBN cord-005646-xhx9pzhj 2564 21 clinical clinical JJ cord-005646-xhx9pzhj 2564 22 significance significance NN cord-005646-xhx9pzhj 2564 23 . . . cord-005646-xhx9pzhj 2565 1 Material material NN cord-005646-xhx9pzhj 2565 2 and and CC cord-005646-xhx9pzhj 2565 3 Methods Methods NNPS cord-005646-xhx9pzhj 2565 4 : : : cord-005646-xhx9pzhj 2565 5 A a DT cord-005646-xhx9pzhj 2565 6 transversal transversal JJ cord-005646-xhx9pzhj 2565 7 study study NN cord-005646-xhx9pzhj 2565 8 was be VBD cord-005646-xhx9pzhj 2565 9 realized realize VBN cord-005646-xhx9pzhj 2565 10 to to TO cord-005646-xhx9pzhj 2565 11 find find VB cord-005646-xhx9pzhj 2565 12 the the DT cord-005646-xhx9pzhj 2565 13 prevalence prevalence NN cord-005646-xhx9pzhj 2565 14 of of IN cord-005646-xhx9pzhj 2565 15 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2565 16 aspiration aspiration NN cord-005646-xhx9pzhj 2565 17 with with IN cord-005646-xhx9pzhj 2565 18 endotracheat endotracheat NNP cord-005646-xhx9pzhj 2565 19 tubes tube NNS cord-005646-xhx9pzhj 2565 20 in in IN cord-005646-xhx9pzhj 2565 21 36 36 CD cord-005646-xhx9pzhj 2565 22 infants infant NNS cord-005646-xhx9pzhj 2565 23 and and CC cord-005646-xhx9pzhj 2565 24 children child NNS cord-005646-xhx9pzhj 2565 25 . . . cord-005646-xhx9pzhj 2566 1 Aspiration aspiration NN cord-005646-xhx9pzhj 2566 2 was be VBD cord-005646-xhx9pzhj 2566 3 assessed assess VBN cord-005646-xhx9pzhj 2566 4 by by IN cord-005646-xhx9pzhj 2566 5 applying apply VBG cord-005646-xhx9pzhj 2566 6 two two CD cord-005646-xhx9pzhj 2566 7 dyes dye NNS cord-005646-xhx9pzhj 2566 8 ( ( -LRB- cord-005646-xhx9pzhj 2566 9 Evans Evans NNP cord-005646-xhx9pzhj 2566 10 Blue Blue NNP cord-005646-xhx9pzhj 2566 11 , , , cord-005646-xhx9pzhj 2566 12 Er)¢rosine Er)¢rosine NNP cord-005646-xhx9pzhj 2566 13 Sodic Sodic NNP cord-005646-xhx9pzhj 2566 14 ) ) -RRB- cord-005646-xhx9pzhj 2566 15 on on IN cord-005646-xhx9pzhj 2566 16 the the DT cord-005646-xhx9pzhj 2566 17 tongue tongue NN cord-005646-xhx9pzhj 2566 18 and and CC cord-005646-xhx9pzhj 2566 19 searching search VBG cord-005646-xhx9pzhj 2566 20 for for IN cord-005646-xhx9pzhj 2566 21 the the DT cord-005646-xhx9pzhj 2566 22 dye dye NN cord-005646-xhx9pzhj 2566 23 during during IN cord-005646-xhx9pzhj 2566 24 suctioning suctioning NN cord-005646-xhx9pzhj 2566 25 in in IN cord-005646-xhx9pzhj 2566 26 the the DT cord-005646-xhx9pzhj 2566 27 endotracheal endotracheal NN cord-005646-xhx9pzhj 2566 28 aspirate aspirate NN cord-005646-xhx9pzhj 2566 29 . . . cord-005646-xhx9pzhj 2567 1 The the DT cord-005646-xhx9pzhj 2567 2 factors factor NNS cord-005646-xhx9pzhj 2567 3 , , , cord-005646-xhx9pzhj 2567 4 that that WDT cord-005646-xhx9pzhj 2567 5 potentially potentially RB cord-005646-xhx9pzhj 2567 6 have have VBP cord-005646-xhx9pzhj 2567 7 influenced influence VBN cord-005646-xhx9pzhj 2567 8 the the DT cord-005646-xhx9pzhj 2567 9 aspiration aspiration NN cord-005646-xhx9pzhj 2567 10 , , , cord-005646-xhx9pzhj 2567 11 including include VBG cord-005646-xhx9pzhj 2567 12 weight weight NN cord-005646-xhx9pzhj 2567 13 , , , cord-005646-xhx9pzhj 2567 14 age age NN cord-005646-xhx9pzhj 2567 15 , , , cord-005646-xhx9pzhj 2567 16 sex sex NN cord-005646-xhx9pzhj 2567 17 , , , cord-005646-xhx9pzhj 2567 18 cause cause NN cord-005646-xhx9pzhj 2567 19 of of IN cord-005646-xhx9pzhj 2567 20 respiratory respiratory JJ cord-005646-xhx9pzhj 2567 21 failure failure NN cord-005646-xhx9pzhj 2567 22 , , , cord-005646-xhx9pzhj 2567 23 main main JJ cord-005646-xhx9pzhj 2567 24 pressure pressure NN cord-005646-xhx9pzhj 2567 25 airway airway NN cord-005646-xhx9pzhj 2567 26 ( ( -LRB- cord-005646-xhx9pzhj 2567 27 MAP MAP NNP cord-005646-xhx9pzhj 2567 28 ) ) -RRB- cord-005646-xhx9pzhj 2567 29 , , , cord-005646-xhx9pzhj 2567 30 level level NN cord-005646-xhx9pzhj 2567 31 of of IN cord-005646-xhx9pzhj 2567 32 consciousness consciousness NN cord-005646-xhx9pzhj 2567 33 , , , cord-005646-xhx9pzhj 2567 34 presence presence NN cord-005646-xhx9pzhj 2567 35 of of IN cord-005646-xhx9pzhj 2567 36 swallowing swallow VBG cord-005646-xhx9pzhj 2567 37 and and CC cord-005646-xhx9pzhj 2567 38 body body NN cord-005646-xhx9pzhj 2567 39 position position NN cord-005646-xhx9pzhj 2567 40 were be VBD cord-005646-xhx9pzhj 2567 41 evaluated evaluate VBN cord-005646-xhx9pzhj 2567 42 . . . cord-005646-xhx9pzhj 2568 1 All all PDT cord-005646-xhx9pzhj 2568 2 the the DT cord-005646-xhx9pzhj 2568 3 variables variable NNS cord-005646-xhx9pzhj 2568 4 studied study VBN cord-005646-xhx9pzhj 2568 5 had have VBD cord-005646-xhx9pzhj 2568 6 their -PRON- PRP$ cord-005646-xhx9pzhj 2568 7 association association NN cord-005646-xhx9pzhj 2568 8 with with IN cord-005646-xhx9pzhj 2568 9 aspiration aspiration NN cord-005646-xhx9pzhj 2568 10 tested test VBN cord-005646-xhx9pzhj 2568 11 by by IN cord-005646-xhx9pzhj 2568 12 chi chi NNP cord-005646-xhx9pzhj 2568 13 - - HYPH cord-005646-xhx9pzhj 2568 14 square square JJ cord-005646-xhx9pzhj 2568 15 Method Method NNP cord-005646-xhx9pzhj 2568 16 with with IN cord-005646-xhx9pzhj 2568 17 Relative Relative NNP cord-005646-xhx9pzhj 2568 18 Risk Risk NNP cord-005646-xhx9pzhj 2568 19 considering consider VBG cord-005646-xhx9pzhj 2568 20 a a DT cord-005646-xhx9pzhj 2568 21 Confidence confidence NN cord-005646-xhx9pzhj 2568 22 Interval interval NN cord-005646-xhx9pzhj 2568 23 of of IN cord-005646-xhx9pzhj 2568 24 95 95 CD cord-005646-xhx9pzhj 2568 25 % % NN cord-005646-xhx9pzhj 2568 26 . . . cord-005646-xhx9pzhj 2569 1 The the DT cord-005646-xhx9pzhj 2569 2 results result NNS cord-005646-xhx9pzhj 2569 3 were be VBD cord-005646-xhx9pzhj 2569 4 adjusted adjust VBN cord-005646-xhx9pzhj 2569 5 by by IN cord-005646-xhx9pzhj 2569 6 multivariate multivariate JJ cord-005646-xhx9pzhj 2569 7 analysis analysis NN cord-005646-xhx9pzhj 2569 8 . . . cord-005646-xhx9pzhj 2570 1 Results result NNS cord-005646-xhx9pzhj 2570 2 : : : cord-005646-xhx9pzhj 2571 1 The the DT cord-005646-xhx9pzhj 2571 2 overall overall JJ cord-005646-xhx9pzhj 2571 3 prevalence prevalence NN cord-005646-xhx9pzhj 2571 4 of of IN cord-005646-xhx9pzhj 2571 5 aspiration aspiration NN cord-005646-xhx9pzhj 2571 6 was be VBD cord-005646-xhx9pzhj 2571 7 36.1 36.1 CD cord-005646-xhx9pzhj 2571 8 % % NN cord-005646-xhx9pzhj 2571 9 . . . cord-005646-xhx9pzhj 2572 1 Among among IN cord-005646-xhx9pzhj 2572 2 all all DT cord-005646-xhx9pzhj 2572 3 children child NNS cord-005646-xhx9pzhj 2572 4 who who WP cord-005646-xhx9pzhj 2572 5 aspirated aspirate VBD cord-005646-xhx9pzhj 2572 6 , , , cord-005646-xhx9pzhj 2572 7 compared compare VBN cord-005646-xhx9pzhj 2572 8 to to IN cord-005646-xhx9pzhj 2572 9 those those DT cord-005646-xhx9pzhj 2572 10 who who WP cord-005646-xhx9pzhj 2572 11 did do VBD cord-005646-xhx9pzhj 2572 12 not not RB cord-005646-xhx9pzhj 2572 13 , , , cord-005646-xhx9pzhj 2572 14 there there EX cord-005646-xhx9pzhj 2572 15 was be VBD cord-005646-xhx9pzhj 2572 16 a a DT cord-005646-xhx9pzhj 2572 17 statistically statistically RB cord-005646-xhx9pzhj 2572 18 significant significant JJ cord-005646-xhx9pzhj 2572 19 difference difference NN cord-005646-xhx9pzhj 2572 20 in in IN cord-005646-xhx9pzhj 2572 21 the the DT cord-005646-xhx9pzhj 2572 22 presence presence NN cord-005646-xhx9pzhj 2572 23 of of IN cord-005646-xhx9pzhj 2572 24 swallowing swallow VBG cord-005646-xhx9pzhj 2572 25 ( ( -LRB- cord-005646-xhx9pzhj 2572 26 p=0.005 p=0.005 NNP cord-005646-xhx9pzhj 2572 27 ) ) -RRB- cord-005646-xhx9pzhj 2572 28 . . . cord-005646-xhx9pzhj 2573 1 The the DT cord-005646-xhx9pzhj 2573 2 odds odd NNS cord-005646-xhx9pzhj 2573 3 ratio ratio NN cord-005646-xhx9pzhj 2573 4 to to IN cord-005646-xhx9pzhj 2573 5 aspiration aspiration NN cord-005646-xhx9pzhj 2573 6 in in IN cord-005646-xhx9pzhj 2573 7 the the DT cord-005646-xhx9pzhj 2573 8 presence presence NN cord-005646-xhx9pzhj 2573 9 of of IN cord-005646-xhx9pzhj 2573 10 swallowing swallowing NN cord-005646-xhx9pzhj 2573 11 was be VBD cord-005646-xhx9pzhj 2573 12 38.4 38.4 CD cord-005646-xhx9pzhj 2573 13 ( ( -LRB- cord-005646-xhx9pzhj 2573 14 t.75 t.75 NNP cord-005646-xhx9pzhj 2573 15 -100 -100 NNP cord-005646-xhx9pzhj 2573 16 C.I.95 C.I.95 NNP cord-005646-xhx9pzhj 2573 17 % % NN cord-005646-xhx9pzhj 2573 18 ) ) -RRB- cord-005646-xhx9pzhj 2573 19 and and CC cord-005646-xhx9pzhj 2573 20 the the DT cord-005646-xhx9pzhj 2573 21 relative relative JJ cord-005646-xhx9pzhj 2573 22 risk risk NN cord-005646-xhx9pzhj 2573 23 55.5 55.5 CD cord-005646-xhx9pzhj 2573 24 . . . cord-005646-xhx9pzhj 2574 1 Aspiration aspiration NN cord-005646-xhx9pzhj 2574 2 was be VBD cord-005646-xhx9pzhj 2574 3 not not RB cord-005646-xhx9pzhj 2574 4 significantly significantly RB cord-005646-xhx9pzhj 2574 5 affected affect VBN cord-005646-xhx9pzhj 2574 6 by by IN cord-005646-xhx9pzhj 2574 7 sex sex NN cord-005646-xhx9pzhj 2574 8 , , , cord-005646-xhx9pzhj 2574 9 weight weight NN cord-005646-xhx9pzhj 2574 10 , , , cord-005646-xhx9pzhj 2574 11 age age NN cord-005646-xhx9pzhj 2574 12 , , , cord-005646-xhx9pzhj 2574 13 cause cause NN cord-005646-xhx9pzhj 2574 14 of of IN cord-005646-xhx9pzhj 2574 15 respiratory respiratory JJ cord-005646-xhx9pzhj 2574 16 failure failure NN cord-005646-xhx9pzhj 2574 17 , , , cord-005646-xhx9pzhj 2574 18 MAP map NN cord-005646-xhx9pzhj 2574 19 , , , cord-005646-xhx9pzhj 2574 20 level level NN cord-005646-xhx9pzhj 2574 21 of of IN cord-005646-xhx9pzhj 2574 22 consciousness consciousness NN cord-005646-xhx9pzhj 2574 23 and and CC cord-005646-xhx9pzhj 2574 24 position position NN cord-005646-xhx9pzhj 2574 25 of of IN cord-005646-xhx9pzhj 2574 26 the the DT cord-005646-xhx9pzhj 2574 27 body body NN cord-005646-xhx9pzhj 2574 28 during during IN cord-005646-xhx9pzhj 2574 29 the the DT cord-005646-xhx9pzhj 2574 30 ventilation ventilation NN cord-005646-xhx9pzhj 2574 31 . . . cord-005646-xhx9pzhj 2575 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2575 2 : : : cord-005646-xhx9pzhj 2576 1 The the DT cord-005646-xhx9pzhj 2576 2 endotracheal endotracheal NN cord-005646-xhx9pzhj 2576 3 intubated intubate VBD cord-005646-xhx9pzhj 2576 4 children child NNS cord-005646-xhx9pzhj 2576 5 frequently frequently RB cord-005646-xhx9pzhj 2576 6 aspirate aspirate VBP cord-005646-xhx9pzhj 2576 7 as as IN cord-005646-xhx9pzhj 2576 8 intubated intubate VBN cord-005646-xhx9pzhj 2576 9 adults adult NNS cord-005646-xhx9pzhj 2576 10 and and CC cord-005646-xhx9pzhj 2576 11 that that IN cord-005646-xhx9pzhj 2576 12 preventive preventive JJ cord-005646-xhx9pzhj 2576 13 measures measure NNS cord-005646-xhx9pzhj 2576 14 are be VBP cord-005646-xhx9pzhj 2576 15 ineffective ineffective JJ cord-005646-xhx9pzhj 2576 16 . . . cord-005646-xhx9pzhj 2577 1 The the DT cord-005646-xhx9pzhj 2577 2 presence presence NN cord-005646-xhx9pzhj 2577 3 of of IN cord-005646-xhx9pzhj 2577 4 swallowing swallow VBG cord-005646-xhx9pzhj 2577 5 movements movement NNS cord-005646-xhx9pzhj 2577 6 is be VBZ cord-005646-xhx9pzhj 2577 7 the the DT cord-005646-xhx9pzhj 2577 8 main main JJ cord-005646-xhx9pzhj 2577 9 risk risk NN cord-005646-xhx9pzhj 2577 10 factor factor NN cord-005646-xhx9pzhj 2577 11 to to IN cord-005646-xhx9pzhj 2577 12 aspiration aspiration NN cord-005646-xhx9pzhj 2577 13 of of IN cord-005646-xhx9pzhj 2577 14 oropharingeal oropharingeal JJ cord-005646-xhx9pzhj 2577 15 content content NN cord-005646-xhx9pzhj 2577 16 in in IN cord-005646-xhx9pzhj 2577 17 intubated intubate VBN cord-005646-xhx9pzhj 2577 18 patients patient NNS cord-005646-xhx9pzhj 2577 19 . . . cord-005646-xhx9pzhj 2578 1 CLINICAL clinical JJ cord-005646-xhx9pzhj 2578 2 FEATURES features NN cord-005646-xhx9pzhj 2578 3 AND and CC cord-005646-xhx9pzhj 2578 4 SHORTTERM shortterm JJ cord-005646-xhx9pzhj 2578 5 OUTCOME outcome NN cord-005646-xhx9pzhj 2578 6 SKling skle VBG cord-005646-xhx9pzhj 2578 7 , , , cord-005646-xhx9pzhj 2578 8 RP RP NNP cord-005646-xhx9pzhj 2578 9 Gie Gie NNP cord-005646-xhx9pzhj 2578 10 Pneumonia Pneumonia NNP cord-005646-xhx9pzhj 2578 11 is be VBZ cord-005646-xhx9pzhj 2578 12 the the DT cord-005646-xhx9pzhj 2578 13 second second JJ cord-005646-xhx9pzhj 2578 14 most most RBS cord-005646-xhx9pzhj 2578 15 important important JJ cord-005646-xhx9pzhj 2578 16 cause cause NN cord-005646-xhx9pzhj 2578 17 of of IN cord-005646-xhx9pzhj 2578 18 death death NN cord-005646-xhx9pzhj 2578 19 in in IN cord-005646-xhx9pzhj 2578 20 young young JJ cord-005646-xhx9pzhj 2578 21 South south JJ cord-005646-xhx9pzhj 2578 22 African african JJ cord-005646-xhx9pzhj 2578 23 children child NNS cord-005646-xhx9pzhj 2578 24 . . . cord-005646-xhx9pzhj 2579 1 The the DT cord-005646-xhx9pzhj 2579 2 clinical clinical JJ cord-005646-xhx9pzhj 2579 3 features feature NNS cord-005646-xhx9pzhj 2579 4 , , , cord-005646-xhx9pzhj 2579 5 intensive intensive JJ cord-005646-xhx9pzhj 2579 6 care care NN cord-005646-xhx9pzhj 2579 7 course course NN cord-005646-xhx9pzhj 2579 8 and and CC cord-005646-xhx9pzhj 2579 9 outcome outcome NN cord-005646-xhx9pzhj 2579 10 of of IN cord-005646-xhx9pzhj 2579 11 children child NNS cord-005646-xhx9pzhj 2579 12 being be VBG cord-005646-xhx9pzhj 2579 13 ventilated ventilate VBN cord-005646-xhx9pzhj 2579 14 for for IN cord-005646-xhx9pzhj 2579 15 pneumonia pneumonia NN cord-005646-xhx9pzhj 2579 16 in in IN cord-005646-xhx9pzhj 2579 17 the the DT cord-005646-xhx9pzhj 2579 18 developing develop VBG cord-005646-xhx9pzhj 2579 19 world world NN cord-005646-xhx9pzhj 2579 20 is be VBZ cord-005646-xhx9pzhj 2579 21 unreported unreported JJ cord-005646-xhx9pzhj 2579 22 . . . cord-005646-xhx9pzhj 2580 1 AIM aim VB cord-005646-xhx9pzhj 2580 2 : : : cord-005646-xhx9pzhj 2581 1 To to TO cord-005646-xhx9pzhj 2581 2 describe describe VB cord-005646-xhx9pzhj 2581 3 the the DT cord-005646-xhx9pzhj 2581 4 clinical clinical JJ cord-005646-xhx9pzhj 2581 5 findings finding NNS cord-005646-xhx9pzhj 2581 6 , , , cord-005646-xhx9pzhj 2581 7 aetiology aetiology NN cord-005646-xhx9pzhj 2581 8 and and CC cord-005646-xhx9pzhj 2581 9 shortterm shortterm JJ cord-005646-xhx9pzhj 2581 10 outcome outcome NN cord-005646-xhx9pzhj 2581 11 of of IN cord-005646-xhx9pzhj 2581 12 children child NNS cord-005646-xhx9pzhj 2581 13 younger young JJR cord-005646-xhx9pzhj 2581 14 than than IN cord-005646-xhx9pzhj 2581 15 6 6 CD cord-005646-xhx9pzhj 2581 16 months month NNS cord-005646-xhx9pzhj 2581 17 with with IN cord-005646-xhx9pzhj 2581 18 pneumonia pneumonia NN cord-005646-xhx9pzhj 2581 19 requiring require VBG cord-005646-xhx9pzhj 2581 20 ventilation ventilation NN cord-005646-xhx9pzhj 2581 21 . . . cord-005646-xhx9pzhj 2582 1 The the DT cord-005646-xhx9pzhj 2582 2 data datum NNS cord-005646-xhx9pzhj 2582 3 of of IN cord-005646-xhx9pzhj 2582 4 all all DT cord-005646-xhx9pzhj 2582 5 babies baby NNS cord-005646-xhx9pzhj 2582 6 under under IN cord-005646-xhx9pzhj 2582 7 the the DT cord-005646-xhx9pzhj 2582 8 age age NN cord-005646-xhx9pzhj 2582 9 of of IN cord-005646-xhx9pzhj 2582 10 six six CD cord-005646-xhx9pzhj 2582 11 months month NNS cord-005646-xhx9pzhj 2582 12 with with IN cord-005646-xhx9pzhj 2582 13 a a DT cord-005646-xhx9pzhj 2582 14 lower low JJR cord-005646-xhx9pzhj 2582 15 respiratory respiratory JJ cord-005646-xhx9pzhj 2582 16 tract tract NN cord-005646-xhx9pzhj 2582 17 infection infection NN cord-005646-xhx9pzhj 2582 18 admitted admit VBD cord-005646-xhx9pzhj 2582 19 to to IN cord-005646-xhx9pzhj 2582 20 the the DT cord-005646-xhx9pzhj 2582 21 Paediatric Paediatric NNP cord-005646-xhx9pzhj 2582 22 ICU ICU NNP cord-005646-xhx9pzhj 2582 23 for for IN cord-005646-xhx9pzhj 2582 24 ventilation ventilation NN cord-005646-xhx9pzhj 2582 25 were be VBD cord-005646-xhx9pzhj 2582 26 prospectively prospectively RB cord-005646-xhx9pzhj 2582 27 collected collect VBN cord-005646-xhx9pzhj 2582 28 over over IN cord-005646-xhx9pzhj 2582 29 a a DT cord-005646-xhx9pzhj 2582 30 period period NN cord-005646-xhx9pzhj 2582 31 of of IN cord-005646-xhx9pzhj 2582 32 14 14 CD cord-005646-xhx9pzhj 2582 33 months month NNS cord-005646-xhx9pzhj 2582 34 . . . cord-005646-xhx9pzhj 2583 1 Tracheal Tracheal NNP cord-005646-xhx9pzhj 2583 2 aspirates aspirate NNS cord-005646-xhx9pzhj 2583 3 and and CC cord-005646-xhx9pzhj 2583 4 blood blood NN cord-005646-xhx9pzhj 2583 5 specimens specimen NNS cord-005646-xhx9pzhj 2583 6 were be VBD cord-005646-xhx9pzhj 2583 7 submitted submit VBN cord-005646-xhx9pzhj 2583 8 for for IN cord-005646-xhx9pzhj 2583 9 viral viral JJ cord-005646-xhx9pzhj 2583 10 and and CC cord-005646-xhx9pzhj 2583 11 bacterial bacterial JJ cord-005646-xhx9pzhj 2583 12 cultures culture NNS cord-005646-xhx9pzhj 2583 13 . . . cord-005646-xhx9pzhj 2584 1 RESULTS result NNS cord-005646-xhx9pzhj 2584 2 : : : cord-005646-xhx9pzhj 2585 1 Forty forty CD cord-005646-xhx9pzhj 2585 2 - - HYPH cord-005646-xhx9pzhj 2585 3 seven seven CD cord-005646-xhx9pzhj 2585 4 babies baby NNS cord-005646-xhx9pzhj 2585 5 aged age VBN cord-005646-xhx9pzhj 2585 6 14 14 CD cord-005646-xhx9pzhj 2585 7 to to TO cord-005646-xhx9pzhj 2585 8 174 174 CD cord-005646-xhx9pzhj 2585 9 days day NNS cord-005646-xhx9pzhj 2585 10 were be VBD cord-005646-xhx9pzhj 2585 11 ventilated ventilate VBN cord-005646-xhx9pzhj 2585 12 for for IN cord-005646-xhx9pzhj 2585 13 pneumonia pneumonia NN cord-005646-xhx9pzhj 2585 14 . . . cord-005646-xhx9pzhj 2586 1 Twenty twenty CD cord-005646-xhx9pzhj 2586 2 - - HYPH cord-005646-xhx9pzhj 2586 3 six six CD cord-005646-xhx9pzhj 2586 4 infants infant NNS cord-005646-xhx9pzhj 2586 5 had have VBD cord-005646-xhx9pzhj 2586 6 been be VBN cord-005646-xhx9pzhj 2586 7 born bear VBN cord-005646-xhx9pzhj 2586 8 prematurely prematurely RB cord-005646-xhx9pzhj 2586 9 ; ; : cord-005646-xhx9pzhj 2586 10 t2 t2 NNP cord-005646-xhx9pzhj 2586 11 had have VBD cord-005646-xhx9pzhj 2586 12 been be VBN cord-005646-xhx9pzhj 2586 13 ventilated ventilate VBN cord-005646-xhx9pzhj 2586 14 during during IN cord-005646-xhx9pzhj 2586 15 the the DT cord-005646-xhx9pzhj 2586 16 neonatal neonatal JJ cord-005646-xhx9pzhj 2586 17 period period NN cord-005646-xhx9pzhj 2586 18 and and CC cord-005646-xhx9pzhj 2586 19 4 4 CD cord-005646-xhx9pzhj 2586 20 had have VBD cord-005646-xhx9pzhj 2586 21 BPD BPD NNS cord-005646-xhx9pzhj 2586 22 . . . cord-005646-xhx9pzhj 2587 1 The the DT cord-005646-xhx9pzhj 2587 2 median median JJ cord-005646-xhx9pzhj 2587 3 duration duration NN cord-005646-xhx9pzhj 2587 4 of of IN cord-005646-xhx9pzhj 2587 5 symptoms symptom NNS cord-005646-xhx9pzhj 2587 6 was be VBD cord-005646-xhx9pzhj 2587 7 1 1 CD cord-005646-xhx9pzhj 2587 8 day day NN cord-005646-xhx9pzhj 2587 9 , , , cord-005646-xhx9pzhj 2587 10 the the DT cord-005646-xhx9pzhj 2587 11 most most RBS cord-005646-xhx9pzhj 2587 12 common common JJ cord-005646-xhx9pzhj 2587 13 being being NN cord-005646-xhx9pzhj 2587 14 cough cough NN cord-005646-xhx9pzhj 2587 15 , , , cord-005646-xhx9pzhj 2587 16 tachypnoea tachypnoea NNS cord-005646-xhx9pzhj 2587 17 , , , cord-005646-xhx9pzhj 2587 18 apnoea apnoea NN cord-005646-xhx9pzhj 2587 19 and and CC cord-005646-xhx9pzhj 2587 20 cyanosis cyanosis NN cord-005646-xhx9pzhj 2587 21 . . . cord-005646-xhx9pzhj 2588 1 Five five CD cord-005646-xhx9pzhj 2588 2 babies baby NNS cord-005646-xhx9pzhj 2588 3 ( ( -LRB- cord-005646-xhx9pzhj 2588 4 10 10 CD cord-005646-xhx9pzhj 2588 5 % % NN cord-005646-xhx9pzhj 2588 6 ) ) -RRB- cord-005646-xhx9pzhj 2588 7 died die VBD cord-005646-xhx9pzhj 2588 8 . . . cord-005646-xhx9pzhj 2589 1 The the DT cord-005646-xhx9pzhj 2589 2 mean mean JJ cord-005646-xhx9pzhj 2589 3 duration duration NN cord-005646-xhx9pzhj 2589 4 of of IN cord-005646-xhx9pzhj 2589 5 ventilation ventilation NN cord-005646-xhx9pzhj 2589 6 was be VBD cord-005646-xhx9pzhj 2589 7 8 8 CD cord-005646-xhx9pzhj 2589 8 days day NNS cord-005646-xhx9pzhj 2589 9 ( ( -LRB- cord-005646-xhx9pzhj 2589 10 range range VB cord-005646-xhx9pzhj 2589 11 1 1 CD cord-005646-xhx9pzhj 2589 12 - - SYM cord-005646-xhx9pzhj 2589 13 85 85 CD cord-005646-xhx9pzhj 2589 14 days day NNS cord-005646-xhx9pzhj 2589 15 ) ) -RRB- cord-005646-xhx9pzhj 2589 16 and and CC cord-005646-xhx9pzhj 2589 17 of of IN cord-005646-xhx9pzhj 2589 18 ward ward NN cord-005646-xhx9pzhj 2589 19 stay stay NN cord-005646-xhx9pzhj 2589 20 after after IN cord-005646-xhx9pzhj 2589 21 ICU ICU NNP cord-005646-xhx9pzhj 2589 22 discharge discharge NN cord-005646-xhx9pzhj 2589 23 19 19 CD cord-005646-xhx9pzhj 2589 24 days day NNS cord-005646-xhx9pzhj 2590 1 ( ( -LRB- cord-005646-xhx9pzhj 2590 2 range range NNP cord-005646-xhx9pzhj 2590 3 1 1 CD cord-005646-xhx9pzhj 2590 4 - - SYM cord-005646-xhx9pzhj 2590 5 161 161 CD cord-005646-xhx9pzhj 2590 6 days day NNS cord-005646-xhx9pzhj 2590 7 ) ) -RRB- cord-005646-xhx9pzhj 2590 8 , , , cord-005646-xhx9pzhj 2590 9 Blood blood NN cord-005646-xhx9pzhj 2590 10 euttures euttures NNPS cord-005646-xhx9pzhj 2590 11 were be VBD cord-005646-xhx9pzhj 2590 12 positive positive JJ cord-005646-xhx9pzhj 2590 13 in in IN cord-005646-xhx9pzhj 2590 14 7 7 CD cord-005646-xhx9pzhj 2590 15 children child NNS cord-005646-xhx9pzhj 2590 16 ( ( -LRB- cord-005646-xhx9pzhj 2590 17 15 15 CD cord-005646-xhx9pzhj 2590 18 % % NN cord-005646-xhx9pzhj 2590 19 ) ) -RRB- cord-005646-xhx9pzhj 2590 20 . . . cord-005646-xhx9pzhj 2591 1 Viruses virus NNS cord-005646-xhx9pzhj 2591 2 were be VBD cord-005646-xhx9pzhj 2591 3 cultured culture VBN cord-005646-xhx9pzhj 2591 4 in in IN cord-005646-xhx9pzhj 2591 5 14 14 CD cord-005646-xhx9pzhj 2591 6 children child NNS cord-005646-xhx9pzhj 2591 7 ( ( -LRB- cord-005646-xhx9pzhj 2591 8 30 30 CD cord-005646-xhx9pzhj 2591 9 % % NN cord-005646-xhx9pzhj 2591 10 ) ) -RRB- cord-005646-xhx9pzhj 2591 11 . . . cord-005646-xhx9pzhj 2592 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 2592 2 : : : cord-005646-xhx9pzhj 2592 3 1 1 LS cord-005646-xhx9pzhj 2592 4 ) ) -RRB- cord-005646-xhx9pzhj 2593 1 Fifty fifty CD cord-005646-xhx9pzhj 2593 2 - - HYPH cord-005646-xhx9pzhj 2593 3 five five CD cord-005646-xhx9pzhj 2593 4 percent percent NN cord-005646-xhx9pzhj 2593 5 of of IN cord-005646-xhx9pzhj 2593 6 children child NNS cord-005646-xhx9pzhj 2593 7 below below IN cord-005646-xhx9pzhj 2593 8 6 6 CD cord-005646-xhx9pzhj 2593 9 months month NNS cord-005646-xhx9pzhj 2593 10 requiring require VBG cord-005646-xhx9pzhj 2593 11 ventilation ventilation NN cord-005646-xhx9pzhj 2593 12 for for IN cord-005646-xhx9pzhj 2593 13 pneumonia pneumonia NN cord-005646-xhx9pzhj 2593 14 were be VBD cord-005646-xhx9pzhj 2593 15 premature premature JJ cord-005646-xhx9pzhj 2593 16 infants infant NNS cord-005646-xhx9pzhj 2593 17 , , , cord-005646-xhx9pzhj 2593 18 of of IN cord-005646-xhx9pzhj 2593 19 whom whom WP cord-005646-xhx9pzhj 2593 20 46 46 CD cord-005646-xhx9pzhj 2593 21 % % NN cord-005646-xhx9pzhj 2593 22 had have VBD cord-005646-xhx9pzhj 2593 23 been be VBN cord-005646-xhx9pzhj 2593 24 ventilated ventilate VBN cord-005646-xhx9pzhj 2593 25 during during IN cord-005646-xhx9pzhj 2593 26 the the DT cord-005646-xhx9pzhj 2593 27 neonatal neonatal JJ cord-005646-xhx9pzhj 2593 28 period period NN cord-005646-xhx9pzhj 2593 29 . . . cord-005646-xhx9pzhj 2594 1 2 2 LS cord-005646-xhx9pzhj 2594 2 ) ) -RRB- cord-005646-xhx9pzhj 2595 1 The the DT cord-005646-xhx9pzhj 2595 2 median median JJ cord-005646-xhx9pzhj 2595 3 duration duration NN cord-005646-xhx9pzhj 2595 4 of of IN cord-005646-xhx9pzhj 2595 5 symptoms symptom NNS cord-005646-xhx9pzhj 2595 6 prior prior RB cord-005646-xhx9pzhj 2595 7 to to IN cord-005646-xhx9pzhj 2595 8 admission admission NN cord-005646-xhx9pzhj 2595 9 was be VBD cord-005646-xhx9pzhj 2595 10 1 1 CD cord-005646-xhx9pzhj 2595 11 day day NN cord-005646-xhx9pzhj 2595 12 . . . cord-005646-xhx9pzhj 2596 1 3 3 LS cord-005646-xhx9pzhj 2596 2 ) ) -RRB- cord-005646-xhx9pzhj 2597 1 Ninety ninety CD cord-005646-xhx9pzhj 2597 2 percent percent NN cord-005646-xhx9pzhj 2597 3 of of IN cord-005646-xhx9pzhj 2597 4 the the DT cord-005646-xhx9pzhj 2597 5 children child NNS cord-005646-xhx9pzhj 2597 6 survived survive VBD cord-005646-xhx9pzhj 2597 7 and and CC cord-005646-xhx9pzhj 2597 8 were be VBD cord-005646-xhx9pzhj 2597 9 discharged discharge VBN cord-005646-xhx9pzhj 2597 10 from from IN cord-005646-xhx9pzhj 2597 11 hospital hospital NN cord-005646-xhx9pzhj 2597 12 . . . cord-005646-xhx9pzhj 2598 1 4 4 LS cord-005646-xhx9pzhj 2598 2 ) ) -RRB- cord-005646-xhx9pzhj 2599 1 Viral viral JJ cord-005646-xhx9pzhj 2599 2 pneumonia pneumonia NN cord-005646-xhx9pzhj 2599 3 was be VBD cord-005646-xhx9pzhj 2599 4 responsible responsible JJ cord-005646-xhx9pzhj 2599 5 for for IN cord-005646-xhx9pzhj 2599 6 30 30 CD cord-005646-xhx9pzhj 2599 7 % % NN cord-005646-xhx9pzhj 2599 8 of of IN cord-005646-xhx9pzhj 2599 9 the the DT cord-005646-xhx9pzhj 2599 10 admissions admission NNS cord-005646-xhx9pzhj 2599 11 . . . cord-005646-xhx9pzhj 2600 1 MECHANICAL mechanical JJ cord-005646-xhx9pzhj 2600 2 VENTILATION VENTILATION NNP cord-005646-xhx9pzhj 2600 3 AND and CC cord-005646-xhx9pzhj 2600 4 ATRIAL ATRIAL NNP cord-005646-xhx9pzhj 2600 5 NATRIURETIC NATRIURETIC NNP cord-005646-xhx9pzhj 2600 6 FACTOR factor NN cord-005646-xhx9pzhj 2601 1 RELEASE RELEASE VBD cord-005646-xhx9pzhj 2601 2 Ulloa Ulloa NNP cord-005646-xhx9pzhj 2601 3 Santamarfa Santamarfa NNP cord-005646-xhx9pzhj 2601 4 , , , cord-005646-xhx9pzhj 2601 5 E E NNP cord-005646-xhx9pzhj 2601 6 , , , cord-005646-xhx9pzhj 2601 7 p6rez p6rez NNP cord-005646-xhx9pzhj 2601 8 Navero Navero NNP cord-005646-xhx9pzhj 2601 9 JL JL NNP cord-005646-xhx9pzhj 2601 10 , , , cord-005646-xhx9pzhj 2601 11 Ibarra Ibarra NNP cord-005646-xhx9pzhj 2601 12 de de NNP cord-005646-xhx9pzhj 2601 13 la la NNP cord-005646-xhx9pzhj 2601 14 Rosa Rosa NNP cord-005646-xhx9pzhj 2602 1 I -PRON- PRP cord-005646-xhx9pzhj 2602 2 , , , cord-005646-xhx9pzhj 2602 3 Espino Espino NNP cord-005646-xhx9pzhj 2602 4 HernLadez HernLadez NNP cord-005646-xhx9pzhj 2602 5 M M NNP cord-005646-xhx9pzhj 2602 6 , , , cord-005646-xhx9pzhj 2602 7 Velasco Velasco NNP cord-005646-xhx9pzhj 2602 8 Jabalquinto Jabalquinto NNP cord-005646-xhx9pzhj 2602 9 MJ MJ NNP cord-005646-xhx9pzhj 2602 10 , , , cord-005646-xhx9pzhj 2602 11 Frfas Frfas NNP cord-005646-xhx9pzhj 2602 12 P6rez P6rez NNP cord-005646-xhx9pzhj 2602 13 M. M. NNP cord-005646-xhx9pzhj 2602 14 PICU PICU NNP cord-005646-xhx9pzhj 2602 15 . . . cord-005646-xhx9pzhj 2603 1 Reina Reina NNP cord-005646-xhx9pzhj 2603 2 Sofia Sofia NNP cord-005646-xhx9pzhj 2603 3 Children Children NNP cord-005646-xhx9pzhj 2603 4 's 's POS cord-005646-xhx9pzhj 2603 5 llospital llospital NNP cord-005646-xhx9pzhj 2603 6 . . . cord-005646-xhx9pzhj 2604 1 C6rdoba C6rdoba NNP cord-005646-xhx9pzhj 2604 2 . . . cord-005646-xhx9pzhj 2605 1 Spain Spain NNP cord-005646-xhx9pzhj 2605 2 . . . cord-005646-xhx9pzhj 2606 1 Mechanical mechanical JJ cord-005646-xhx9pzhj 2606 2 ventilation ventilation NN cord-005646-xhx9pzhj 2606 3 effects effect NNS cord-005646-xhx9pzhj 2606 4 on on IN cord-005646-xhx9pzhj 2606 5 renal renal JJ cord-005646-xhx9pzhj 2606 6 function function NN cord-005646-xhx9pzhj 2606 7 decreased decrease VBD cord-005646-xhx9pzhj 2606 8 diuresis diuresis NN cord-005646-xhx9pzhj 2606 9 and and CC cord-005646-xhx9pzhj 2606 10 natriuresis natriuresis NN cord-005646-xhx9pzhj 2606 11 due due JJ cord-005646-xhx9pzhj 2606 12 several several JJ cord-005646-xhx9pzhj 2606 13 factors factor NNS cord-005646-xhx9pzhj 2606 14 including include VBG cord-005646-xhx9pzhj 2606 15 ANF ANF NNP cord-005646-xhx9pzhj 2606 16 . . . cord-005646-xhx9pzhj 2607 1 Several several JJ cord-005646-xhx9pzhj 2607 2 studies study NNS cord-005646-xhx9pzhj 2607 3 have have VBP cord-005646-xhx9pzhj 2607 4 demostrated demostrate VBN cord-005646-xhx9pzhj 2607 5 ANF ANF NNP cord-005646-xhx9pzhj 2607 6 released release VBD cord-005646-xhx9pzhj 2607 7 due due JJ cord-005646-xhx9pzhj 2607 8 increaasing increaase VBG cord-005646-xhx9pzhj 2607 9 pressure pressure NN cord-005646-xhx9pzhj 2607 10 in in IN cord-005646-xhx9pzhj 2607 11 right right JJ cord-005646-xhx9pzhj 2607 12 atrium atrium NN cord-005646-xhx9pzhj 2607 13 . . . cord-005646-xhx9pzhj 2608 1 On on IN cord-005646-xhx9pzhj 2608 2 the the DT cord-005646-xhx9pzhj 2608 3 other other JJ cord-005646-xhx9pzhj 2608 4 hand hand NN cord-005646-xhx9pzhj 2608 5 , , , cord-005646-xhx9pzhj 2608 6 mechanical mechanical JJ cord-005646-xhx9pzhj 2608 7 ventilation ventilation NN cord-005646-xhx9pzhj 2608 8 , , , cord-005646-xhx9pzhj 2608 9 overall overall JJ cord-005646-xhx9pzhj 2608 10 PEEP peep NN cord-005646-xhx9pzhj 2608 11 modality modality NN cord-005646-xhx9pzhj 2608 12 , , , cord-005646-xhx9pzhj 2608 13 inhibits inhibit VBZ cord-005646-xhx9pzhj 2608 14 peptide peptide NN cord-005646-xhx9pzhj 2608 15 release release NN cord-005646-xhx9pzhj 2608 16 althougt althougt NNP cord-005646-xhx9pzhj 2608 17 CVP CVP NNP cord-005646-xhx9pzhj 2608 18 increased increase VBD cord-005646-xhx9pzhj 2608 19 is be VBZ cord-005646-xhx9pzhj 2608 20 found find VBN cord-005646-xhx9pzhj 2608 21 . . . cord-005646-xhx9pzhj 2609 1 This this DT cord-005646-xhx9pzhj 2609 2 study study NN cord-005646-xhx9pzhj 2609 3 was be VBD cord-005646-xhx9pzhj 2609 4 designed design VBN cord-005646-xhx9pzhj 2609 5 to to TO cord-005646-xhx9pzhj 2609 6 demostrate demostrate VB cord-005646-xhx9pzhj 2609 7 ANF ANF NNP cord-005646-xhx9pzhj 2609 8 stimulation stimulation NN cord-005646-xhx9pzhj 2609 9 is be VBZ cord-005646-xhx9pzhj 2609 10 due due JJ cord-005646-xhx9pzhj 2609 11 rigth rigth NNP cord-005646-xhx9pzhj 2609 12 atrium atrium NNP cord-005646-xhx9pzhj 2609 13 stretch stretch NN cord-005646-xhx9pzhj 2609 14 which which WDT cord-005646-xhx9pzhj 2609 15 be be VB cord-005646-xhx9pzhj 2609 16 higher high JJR cord-005646-xhx9pzhj 2609 17 during during IN cord-005646-xhx9pzhj 2609 18 mechanical mechanical JJ cord-005646-xhx9pzhj 2609 19 ventilation ventilation NN cord-005646-xhx9pzhj 2609 20 instead instead RB cord-005646-xhx9pzhj 2609 21 of of IN cord-005646-xhx9pzhj 2609 22 atrium atrium NN cord-005646-xhx9pzhj 2609 23 pressure pressure NN cord-005646-xhx9pzhj 2609 24 . . . cord-005646-xhx9pzhj 2610 1 We -PRON- PRP cord-005646-xhx9pzhj 2610 2 desing dese VBD cord-005646-xhx9pzhj 2610 3 a a DT cord-005646-xhx9pzhj 2610 4 prospective prospective JJ cord-005646-xhx9pzhj 2610 5 study study NN cord-005646-xhx9pzhj 2610 6 including include VBG cord-005646-xhx9pzhj 2610 7 14 14 CD cord-005646-xhx9pzhj 2610 8 patients patient NNS cord-005646-xhx9pzhj 2610 9 , , , cord-005646-xhx9pzhj 2610 10 age age NN cord-005646-xhx9pzhj 2610 11 range range NN cord-005646-xhx9pzhj 2610 12 16 16 CD cord-005646-xhx9pzhj 2610 13 months-13 months-13 CD cord-005646-xhx9pzhj 2610 14 years year NNS cord-005646-xhx9pzhj 2610 15 with with IN cord-005646-xhx9pzhj 2610 16 congenital congenital JJ cord-005646-xhx9pzhj 2610 17 heart heart NN cord-005646-xhx9pzhj 2610 18 disease disease NN cord-005646-xhx9pzhj 2610 19 . . . cord-005646-xhx9pzhj 2611 1 All all DT cord-005646-xhx9pzhj 2611 2 of of IN cord-005646-xhx9pzhj 2611 3 them -PRON- PRP cord-005646-xhx9pzhj 2611 4 were be VBD cord-005646-xhx9pzhj 2611 5 admitted admit VBN cord-005646-xhx9pzhj 2611 6 at at IN cord-005646-xhx9pzhj 2611 7 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2611 8 Intensive Intensive NNP cord-005646-xhx9pzhj 2611 9 Care Care NNP cord-005646-xhx9pzhj 2611 10 Unit Unit NNP cord-005646-xhx9pzhj 2611 11 after after IN cord-005646-xhx9pzhj 2611 12 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 2611 13 surgery surgery NN cord-005646-xhx9pzhj 2611 14 and and CC cord-005646-xhx9pzhj 2611 15 were be VBD cord-005646-xhx9pzhj 2611 16 assisted assist VBN cord-005646-xhx9pzhj 2611 17 by by IN cord-005646-xhx9pzhj 2611 18 mechanical mechanical JJ cord-005646-xhx9pzhj 2611 19 ventilation ventilation NN cord-005646-xhx9pzhj 2611 20 . . . cord-005646-xhx9pzhj 2612 1 Hemodinamic Hemodinamic NNP cord-005646-xhx9pzhj 2612 2 state state NN cord-005646-xhx9pzhj 2612 3 was be VBD cord-005646-xhx9pzhj 2612 4 stabilized stabilize VBN cord-005646-xhx9pzhj 2612 5 in in IN cord-005646-xhx9pzhj 2612 6 all all DT cord-005646-xhx9pzhj 2612 7 patients patient NNS cord-005646-xhx9pzhj 2612 8 and and CC cord-005646-xhx9pzhj 2612 9 nor nor CC cord-005646-xhx9pzhj 2612 10 renal renal JJ cord-005646-xhx9pzhj 2612 11 neither neither CC cord-005646-xhx9pzhj 2612 12 neurological neurological JJ cord-005646-xhx9pzhj 2612 13 diseases disease NNS cord-005646-xhx9pzhj 2612 14 were be VBD cord-005646-xhx9pzhj 2612 15 found find VBN cord-005646-xhx9pzhj 2612 16 . . . cord-005646-xhx9pzhj 2613 1 After after IN cord-005646-xhx9pzhj 2613 2 24 24 CD cord-005646-xhx9pzhj 2613 3 hours hour NNS cord-005646-xhx9pzhj 2613 4 with with IN cord-005646-xhx9pzhj 2613 5 mechanical mechanical JJ cord-005646-xhx9pzhj 2613 6 ventilation ventilation NN cord-005646-xhx9pzhj 2613 7 , , , cord-005646-xhx9pzhj 2613 8 plasmatic plasmatic JJ cord-005646-xhx9pzhj 2613 9 levels level NNS cord-005646-xhx9pzhj 2613 10 of of IN cord-005646-xhx9pzhj 2613 11 ANF ANF NNP cord-005646-xhx9pzhj 2613 12 were be VBD cord-005646-xhx9pzhj 2613 13 measurement measurement NN cord-005646-xhx9pzhj 2613 14 , , , cord-005646-xhx9pzhj 2613 15 PVC PVC NNP cord-005646-xhx9pzhj 2613 16 , , , cord-005646-xhx9pzhj 2613 17 pericardical pericardical JJ cord-005646-xhx9pzhj 2613 18 pressure pressure NN cord-005646-xhx9pzhj 2613 19 were be VBD cord-005646-xhx9pzhj 2613 20 assessment assessment NN cord-005646-xhx9pzhj 2613 21 ; ; : cord-005646-xhx9pzhj 2613 22 all all DT cord-005646-xhx9pzhj 2613 23 patient patient JJ cord-005646-xhx9pzhj 2613 24 were be VBD cord-005646-xhx9pzhj 2613 25 sedated sedate VBN cord-005646-xhx9pzhj 2613 26 with with IN cord-005646-xhx9pzhj 2613 27 midazolan midazolan NNP cord-005646-xhx9pzhj 2613 28 and and CC cord-005646-xhx9pzhj 2613 29 paralized paralize VBN cord-005646-xhx9pzhj 2613 30 with with IN cord-005646-xhx9pzhj 2613 31 neuromuscular neuromuscular NN cord-005646-xhx9pzhj 2613 32 blocking block VBG cord-005646-xhx9pzhj 2613 33 agent agent NN cord-005646-xhx9pzhj 2613 34 ; ; : cord-005646-xhx9pzhj 2613 35 mechanical mechanical JJ cord-005646-xhx9pzhj 2613 36 ventilation ventilation NN cord-005646-xhx9pzhj 2613 37 technique technique NN cord-005646-xhx9pzhj 2613 38 was be VBD cord-005646-xhx9pzhj 2613 39 as as IN cord-005646-xhx9pzhj 2613 40 follow follow NN cord-005646-xhx9pzhj 2613 41 : : : cord-005646-xhx9pzhj 2613 42 IMV IMV NNP cord-005646-xhx9pzhj 2613 43 between between IN cord-005646-xhx9pzhj 2613 44 20 20 CD cord-005646-xhx9pzhj 2613 45 and and CC cord-005646-xhx9pzhj 2613 46 30 30 CD cord-005646-xhx9pzhj 2613 47 , , , cord-005646-xhx9pzhj 2613 48 tidal tidal JJ cord-005646-xhx9pzhj 2613 49 volume volume NN cord-005646-xhx9pzhj 2613 50 and and CC cord-005646-xhx9pzhj 2613 51 Fi Fi NNP cord-005646-xhx9pzhj 2613 52 O2 O2 NNP cord-005646-xhx9pzhj 2613 53 enough enough RB cord-005646-xhx9pzhj 2613 54 to to TO cord-005646-xhx9pzhj 2613 55 mantain mantain VB cord-005646-xhx9pzhj 2613 56 respiratory respiratory JJ cord-005646-xhx9pzhj 2613 57 parameters parameter NNS cord-005646-xhx9pzhj 2613 58 in in IN cord-005646-xhx9pzhj 2613 59 normal normal JJ cord-005646-xhx9pzhj 2613 60 range range NN cord-005646-xhx9pzhj 2613 61 . . . cord-005646-xhx9pzhj 2614 1 Afterwards afterwards RB cord-005646-xhx9pzhj 2614 2 , , , cord-005646-xhx9pzhj 2614 3 at at IN cord-005646-xhx9pzhj 2614 4 least least JJS cord-005646-xhx9pzhj 2614 5 twentyfour twentyfour NN cord-005646-xhx9pzhj 2614 6 hours hour NNS cord-005646-xhx9pzhj 2614 7 in in IN cord-005646-xhx9pzhj 2614 8 spontaneous spontaneous JJ cord-005646-xhx9pzhj 2614 9 breathing breathing NN cord-005646-xhx9pzhj 2614 10 , , , cord-005646-xhx9pzhj 2614 11 the the DT cord-005646-xhx9pzhj 2614 12 study study NN cord-005646-xhx9pzhj 2614 13 was be VBD cord-005646-xhx9pzhj 2614 14 made make VBN cord-005646-xhx9pzhj 2614 15 again again RB cord-005646-xhx9pzhj 2614 16 in in IN cord-005646-xhx9pzhj 2614 17 each each DT cord-005646-xhx9pzhj 2614 18 patient patient NN cord-005646-xhx9pzhj 2614 19 . . . cord-005646-xhx9pzhj 2615 1 Atrial atrial JJ cord-005646-xhx9pzhj 2615 2 stretch stretch NN cord-005646-xhx9pzhj 2615 3 was be VBD cord-005646-xhx9pzhj 2615 4 assesssment assesssment NN cord-005646-xhx9pzhj 2615 5 according accord VBG cord-005646-xhx9pzhj 2615 6 to to IN cord-005646-xhx9pzhj 2615 7 following follow VBG cord-005646-xhx9pzhj 2615 8 equation equation NN cord-005646-xhx9pzhj 2615 9 : : : cord-005646-xhx9pzhj 2616 1 Transmural Transmural NNP cord-005646-xhx9pzhj 2616 2 pressure= pressure= NN cord-005646-xhx9pzhj 2616 3 CVP CVP NNP cord-005646-xhx9pzhj 2616 4 -Pericardial -pericardial JJ cord-005646-xhx9pzhj 2616 5 pressure pressure NN cord-005646-xhx9pzhj 2616 6 . . . cord-005646-xhx9pzhj 2617 1 CVP CVP NNP cord-005646-xhx9pzhj 2617 2 were be VBD cord-005646-xhx9pzhj 2617 3 significantly significantly RB cord-005646-xhx9pzhj 2617 4 higher high JJR cord-005646-xhx9pzhj 2617 5 with with IN cord-005646-xhx9pzhj 2617 6 mechanical mechanical JJ cord-005646-xhx9pzhj 2617 7 ventilation ventilation NN cord-005646-xhx9pzhj 2617 8 than than IN cord-005646-xhx9pzhj 2617 9 when when WRB cord-005646-xhx9pzhj 2617 10 the the DT cord-005646-xhx9pzhj 2617 11 patient patient NN cord-005646-xhx9pzhj 2617 12 was be VBD cord-005646-xhx9pzhj 2617 13 breathing breathe VBG cord-005646-xhx9pzhj 2617 14 by by IN cord-005646-xhx9pzhj 2617 15 himself -PRON- PRP cord-005646-xhx9pzhj 2617 16 . . . cord-005646-xhx9pzhj 2618 1 ( ( -LRB- cord-005646-xhx9pzhj 2618 2 5.4 5.4 CD cord-005646-xhx9pzhj 2618 3 + + CC cord-005646-xhx9pzhj 2618 4 _ _ NN cord-005646-xhx9pzhj 2618 5 _ _ NN cord-005646-xhx9pzhj 2618 6 2.2 2.2 CD cord-005646-xhx9pzhj 2618 7 vs vs IN cord-005646-xhx9pzhj 2618 8 3.8 3.8 CD cord-005646-xhx9pzhj 2618 9 + + SYM cord-005646-xhx9pzhj 2618 10 1.8 1.8 CD cord-005646-xhx9pzhj 2618 11 mm mm NN cord-005646-xhx9pzhj 2618 12 Hg hg NN cord-005646-xhx9pzhj 2618 13 ; ; : cord-005646-xhx9pzhj 2618 14 p<0.01 p<0.01 NN cord-005646-xhx9pzhj 2618 15 ) ) -RRB- cord-005646-xhx9pzhj 2618 16 . . . cord-005646-xhx9pzhj 2619 1 However however RB cord-005646-xhx9pzhj 2619 2 , , , cord-005646-xhx9pzhj 2619 3 transmural transmural JJ cord-005646-xhx9pzhj 2619 4 pressure pressure NN cord-005646-xhx9pzhj 2619 5 during during IN cord-005646-xhx9pzhj 2619 6 mechanical mechanical JJ cord-005646-xhx9pzhj 2619 7 ventilation ventilation NN cord-005646-xhx9pzhj 2619 8 were be VBD cord-005646-xhx9pzhj 2619 9 lower low JJR cord-005646-xhx9pzhj 2619 10 than than IN cord-005646-xhx9pzhj 2619 11 during during IN cord-005646-xhx9pzhj 2619 12 spontaneous spontaneous JJ cord-005646-xhx9pzhj 2619 13 breathing breathing NN cord-005646-xhx9pzhj 2619 14 ( ( -LRB- cord-005646-xhx9pzhj 2619 15 8.92 8.92 CD cord-005646-xhx9pzhj 2619 16 + + CC cord-005646-xhx9pzhj 2619 17 _ _ NN cord-005646-xhx9pzhj 2619 18 _ _ NNP cord-005646-xhx9pzhj 2619 19 3.86 3.86 CD cord-005646-xhx9pzhj 2619 20 vs vs IN cord-005646-xhx9pzhj 2619 21 11.76 11.76 CD cord-005646-xhx9pzhj 2619 22 + + CC cord-005646-xhx9pzhj 2619 23 _ _ NN cord-005646-xhx9pzhj 2619 24 _ _ NN cord-005646-xhx9pzhj 2619 25 3.32 3.32 CD cord-005646-xhx9pzhj 2619 26 mm mm NNP cord-005646-xhx9pzhj 2619 27 Hg hg NN cord-005646-xhx9pzhj 2619 28 ; ; : cord-005646-xhx9pzhj 2619 29 p p NN cord-005646-xhx9pzhj 2619 30 < < XX cord-005646-xhx9pzhj 2619 31 0.01 0.01 CD cord-005646-xhx9pzhj 2619 32 ) ) -RRB- cord-005646-xhx9pzhj 2620 1 Equal equal JJ cord-005646-xhx9pzhj 2620 2 , , , cord-005646-xhx9pzhj 2620 3 plasmatic plasmatic JJ cord-005646-xhx9pzhj 2620 4 ANF ANF NNP cord-005646-xhx9pzhj 2620 5 levels level NNS cord-005646-xhx9pzhj 2620 6 were be VBD cord-005646-xhx9pzhj 2620 7 lower low JJR cord-005646-xhx9pzhj 2620 8 during during IN cord-005646-xhx9pzhj 2620 9 mechanical mechanical JJ cord-005646-xhx9pzhj 2620 10 ventilation ventilation NN cord-005646-xhx9pzhj 2620 11 ( ( -LRB- cord-005646-xhx9pzhj 2620 12 87.77 87.77 CD cord-005646-xhx9pzhj 2620 13 + + SYM cord-005646-xhx9pzhj 2620 14 46.55 46.55 CD cord-005646-xhx9pzhj 2620 15 vs vs IN cord-005646-xhx9pzhj 2620 16 108.92 108.92 CD cord-005646-xhx9pzhj 2620 17 + + SYM cord-005646-xhx9pzhj 2620 18 49.06 49.06 CD cord-005646-xhx9pzhj 2620 19 pg pg NNP cord-005646-xhx9pzhj 2620 20 / / SYM cord-005646-xhx9pzhj 2620 21 rnl rnl NNP cord-005646-xhx9pzhj 2620 22 ; ; : cord-005646-xhx9pzhj 2620 23 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 2620 24 ) ) -RRB- cord-005646-xhx9pzhj 2620 25 . . . cord-005646-xhx9pzhj 2621 1 In in IN cord-005646-xhx9pzhj 2621 2 conclusion conclusion NN cord-005646-xhx9pzhj 2621 3 , , , cord-005646-xhx9pzhj 2621 4 ANF ANF NNP cord-005646-xhx9pzhj 2621 5 secretion secretion NN cord-005646-xhx9pzhj 2621 6 decreases decrease VBZ cord-005646-xhx9pzhj 2621 7 during during IN cord-005646-xhx9pzhj 2621 8 mechanical mechanical JJ cord-005646-xhx9pzhj 2621 9 ventilation ventilation NN cord-005646-xhx9pzhj 2621 10 , , , cord-005646-xhx9pzhj 2621 11 even even RB cord-005646-xhx9pzhj 2621 12 with with IN cord-005646-xhx9pzhj 2621 13 CVP CVP NNP cord-005646-xhx9pzhj 2621 14 higher higher RBR cord-005646-xhx9pzhj 2621 15 . . . cord-005646-xhx9pzhj 2622 1 ANF ANF NNP cord-005646-xhx9pzhj 2622 2 release release NN cord-005646-xhx9pzhj 2622 3 would would MD cord-005646-xhx9pzhj 2622 4 depend depend VB cord-005646-xhx9pzhj 2622 5 on on IN cord-005646-xhx9pzhj 2622 6 atrial atrial JJ cord-005646-xhx9pzhj 2622 7 stretch stretch NN cord-005646-xhx9pzhj 2622 8 meassured meassure VBN cord-005646-xhx9pzhj 2622 9 by by IN cord-005646-xhx9pzhj 2622 10 transmural transmural NNP cord-005646-xhx9pzhj 2622 11 pressure pressure NN cord-005646-xhx9pzhj 2622 12 , , , cord-005646-xhx9pzhj 2622 13 lower low JJR cord-005646-xhx9pzhj 2622 14 in in IN cord-005646-xhx9pzhj 2622 15 patients patient NNS cord-005646-xhx9pzhj 2622 16 with with IN cord-005646-xhx9pzhj 2622 17 mechanical mechanical JJ cord-005646-xhx9pzhj 2622 18 ventilation ventilation NN cord-005646-xhx9pzhj 2622 19 and and CC cord-005646-xhx9pzhj 2622 20 it -PRON- PRP cord-005646-xhx9pzhj 2622 21 would would MD cord-005646-xhx9pzhj 2622 22 not not RB cord-005646-xhx9pzhj 2622 23 depend depend VB cord-005646-xhx9pzhj 2622 24 on on IN cord-005646-xhx9pzhj 2622 25 atrial atrial JJ cord-005646-xhx9pzhj 2622 26 pressure pressure NN cord-005646-xhx9pzhj 2622 27 . . . cord-005646-xhx9pzhj 2623 1 The the DT cord-005646-xhx9pzhj 2623 2 Paediatric paediatric JJ cord-005646-xhx9pzhj 2623 3 intensive intensive JJ cord-005646-xhx9pzhj 2623 4 care care NN cord-005646-xhx9pzhj 2623 5 unit unit NN cord-005646-xhx9pzhj 2623 6 Shaikh Shaikh NNP cord-005646-xhx9pzhj 2623 7 Zayed Zayed NNP cord-005646-xhx9pzhj 2623 8 Hospital Hospital NNP cord-005646-xhx9pzhj 2623 9 , , , cord-005646-xhx9pzhj 2623 10 Lahore Lahore NNP cord-005646-xhx9pzhj 2623 11 is be VBZ cord-005646-xhx9pzhj 2623 12 an an DT cord-005646-xhx9pzhj 2623 13 acute acute JJ cord-005646-xhx9pzhj 2623 14 care care NN cord-005646-xhx9pzhj 2623 15 area area NN cord-005646-xhx9pzhj 2623 16 devoted devote VBN cord-005646-xhx9pzhj 2623 17 to to IN cord-005646-xhx9pzhj 2623 18 the the DT cord-005646-xhx9pzhj 2623 19 care care NN cord-005646-xhx9pzhj 2623 20 of of IN cord-005646-xhx9pzhj 2623 21 critically critically RB cord-005646-xhx9pzhj 2623 22 sick sick JJ cord-005646-xhx9pzhj 2623 23 children child NNS cord-005646-xhx9pzhj 2623 24 upto upto IN cord-005646-xhx9pzhj 2623 25 the the DT cord-005646-xhx9pzhj 2623 26 age age NN cord-005646-xhx9pzhj 2623 27 of of IN cord-005646-xhx9pzhj 2623 28 13 13 CD cord-005646-xhx9pzhj 2623 29 years year NNS cord-005646-xhx9pzhj 2623 30 . . . cord-005646-xhx9pzhj 2624 1 In in IN cord-005646-xhx9pzhj 2624 2 a a DT cord-005646-xhx9pzhj 2624 3 6 6 CD cord-005646-xhx9pzhj 2624 4 bedded bedded JJ cord-005646-xhx9pzhj 2624 5 unit unit NN cord-005646-xhx9pzhj 2624 6 with with IN cord-005646-xhx9pzhj 2624 7 limited limited JJ cord-005646-xhx9pzhj 2624 8 equipment equipment NN cord-005646-xhx9pzhj 2624 9 , , , cord-005646-xhx9pzhj 2624 10 constant constant JJ cord-005646-xhx9pzhj 2624 11 care care NN cord-005646-xhx9pzhj 2624 12 is be VBZ cord-005646-xhx9pzhj 2624 13 ensured ensure VBN cord-005646-xhx9pzhj 2624 14 by by IN cord-005646-xhx9pzhj 2624 15 the the DT cord-005646-xhx9pzhj 2624 16 presence presence NN cord-005646-xhx9pzhj 2624 17 of of IN cord-005646-xhx9pzhj 2624 18 at at RB cord-005646-xhx9pzhj 2624 19 least least RBS cord-005646-xhx9pzhj 2624 20 one one CD cord-005646-xhx9pzhj 2624 21 nurse nurse NN cord-005646-xhx9pzhj 2624 22 aed aed NNP cord-005646-xhx9pzhj 2624 23 one one CD cord-005646-xhx9pzhj 2624 24 doctor doctor NN cord-005646-xhx9pzhj 2624 25 round round IN cord-005646-xhx9pzhj 2624 26 the the DT cord-005646-xhx9pzhj 2624 27 clock clock NN cord-005646-xhx9pzhj 2624 28 . . . cord-005646-xhx9pzhj 2625 1 In in IN cord-005646-xhx9pzhj 2625 2 this this DT cord-005646-xhx9pzhj 2625 3 setup setup NN cord-005646-xhx9pzhj 2625 4 we -PRON- PRP cord-005646-xhx9pzhj 2625 5 have have VBP cord-005646-xhx9pzhj 2625 6 the the DT cord-005646-xhx9pzhj 2625 7 facility facility NN cord-005646-xhx9pzhj 2625 8 to to TO cord-005646-xhx9pzhj 2625 9 ventilate ventilate VB cord-005646-xhx9pzhj 2625 10 2 2 CD cord-005646-xhx9pzhj 2625 11 - - SYM cord-005646-xhx9pzhj 2625 12 3 3 CD cord-005646-xhx9pzhj 2625 13 children child NNS cord-005646-xhx9pzhj 2625 14 at at IN cord-005646-xhx9pzhj 2625 15 one one CD cord-005646-xhx9pzhj 2625 16 time time NN cord-005646-xhx9pzhj 2625 17 , , , cord-005646-xhx9pzhj 2625 18 Between between IN cord-005646-xhx9pzhj 2625 19 Sep. September NNP cord-005646-xhx9pzhj 2625 20 93 93 CD cord-005646-xhx9pzhj 2625 21 and and CC cord-005646-xhx9pzhj 2625 22 Dec. December NNP cord-005646-xhx9pzhj 2625 23 95 95 CD cord-005646-xhx9pzhj 2625 24 , , , cord-005646-xhx9pzhj 2625 25 out out IN cord-005646-xhx9pzhj 2625 26 of of IN cord-005646-xhx9pzhj 2625 27 885 885 CD cord-005646-xhx9pzhj 2625 28 patients patient NNS cord-005646-xhx9pzhj 2625 29 admitted admit VBN cord-005646-xhx9pzhj 2625 30 to to IN cord-005646-xhx9pzhj 2625 31 ICU ICU NNP cord-005646-xhx9pzhj 2625 32 , , , cord-005646-xhx9pzhj 2625 33 171 171 CD cord-005646-xhx9pzhj 2625 34 ( ( -LRB- cord-005646-xhx9pzhj 2625 35 19.32 19.32 CD cord-005646-xhx9pzhj 2625 36 % % NN cord-005646-xhx9pzhj 2625 37 ) ) -RRB- cord-005646-xhx9pzhj 2625 38 were be VBD cord-005646-xhx9pzhj 2625 39 below below IN cord-005646-xhx9pzhj 2625 40 1 1 CD cord-005646-xhx9pzhj 2625 41 yr yr NN cord-005646-xhx9pzhj 2625 42 of of IN cord-005646-xhx9pzhj 2625 43 age age NN cord-005646-xhx9pzhj 2625 44 , , , cord-005646-xhx9pzhj 2625 45 while while IN cord-005646-xhx9pzhj 2625 46 48 48 CD cord-005646-xhx9pzhj 2625 47 ( ( -LRB- cord-005646-xhx9pzhj 2625 48 28 28 CD cord-005646-xhx9pzhj 2625 49 % % NN cord-005646-xhx9pzhj 2625 50 ) ) -RRB- cord-005646-xhx9pzhj 2625 51 were be VBD cord-005646-xhx9pzhj 2625 52 below below IN cord-005646-xhx9pzhj 2625 53 1 1 CD cord-005646-xhx9pzhj 2625 54 month month NN cord-005646-xhx9pzhj 2625 55 of of IN cord-005646-xhx9pzhj 2625 56 age age NN cord-005646-xhx9pzhj 2625 57 . . . cord-005646-xhx9pzhj 2626 1 Life life NN cord-005646-xhx9pzhj 2626 2 support support NN cord-005646-xhx9pzhj 2626 3 was be VBD cord-005646-xhx9pzhj 2626 4 discontinued discontinue VBN cord-005646-xhx9pzhj 2626 5 in in IN cord-005646-xhx9pzhj 2626 6 17 17 CD cord-005646-xhx9pzhj 2626 7 ( ( -LRB- cord-005646-xhx9pzhj 2626 8 9.9 9.9 CD cord-005646-xhx9pzhj 2626 9 % % NN cord-005646-xhx9pzhj 2626 10 ) ) -RRB- cord-005646-xhx9pzhj 2626 11 . . . cord-005646-xhx9pzhj 2627 1 Total total JJ cord-005646-xhx9pzhj 2627 2 mortality mortality NN cord-005646-xhx9pzhj 2627 3 was be VBD cord-005646-xhx9pzhj 2627 4 56 56 CD cord-005646-xhx9pzhj 2627 5 ( ( -LRB- cord-005646-xhx9pzhj 2627 6 32.7 32.7 CD cord-005646-xhx9pzhj 2627 7 % % NN cord-005646-xhx9pzhj 2627 8 ) ) -RRB- cord-005646-xhx9pzhj 2627 9 , , , cord-005646-xhx9pzhj 2627 10 Major major JJ cord-005646-xhx9pzhj 2627 11 mortality mortality NN cord-005646-xhx9pzhj 2627 12 was be VBD cord-005646-xhx9pzhj 2627 13 in in IN cord-005646-xhx9pzhj 2627 14 0 0 CD cord-005646-xhx9pzhj 2627 15 - - SYM cord-005646-xhx9pzhj 2627 16 1 1 CD cord-005646-xhx9pzhj 2627 17 month month NN cord-005646-xhx9pzhj 2627 18 age age NN cord-005646-xhx9pzhj 2627 19 group group NN cord-005646-xhx9pzhj 2627 20 22 22 CD cord-005646-xhx9pzhj 2627 21 ( ( -LRB- cord-005646-xhx9pzhj 2627 22 12.8 12.8 CD cord-005646-xhx9pzhj 2627 23 % % NN cord-005646-xhx9pzhj 2627 24 ) ) -RRB- cord-005646-xhx9pzhj 2627 25 , , , cord-005646-xhx9pzhj 2627 26 and and CC cord-005646-xhx9pzhj 2627 27 1 1 CD cord-005646-xhx9pzhj 2627 28 month month NN cord-005646-xhx9pzhj 2627 29 to to IN cord-005646-xhx9pzhj 2627 30 6 6 CD cord-005646-xhx9pzhj 2627 31 month month NN cord-005646-xhx9pzhj 2627 32 15 15 CD cord-005646-xhx9pzhj 2627 33 ( ( -LRB- cord-005646-xhx9pzhj 2627 34 8.7 8.7 CD cord-005646-xhx9pzhj 2627 35 % % NN cord-005646-xhx9pzhj 2627 36 ) ) -RRB- cord-005646-xhx9pzhj 2627 37 . . . cord-005646-xhx9pzhj 2628 1 Majority majority NN cord-005646-xhx9pzhj 2628 2 of of IN cord-005646-xhx9pzhj 2628 3 the the DT cord-005646-xhx9pzhj 2628 4 patients patient NNS cord-005646-xhx9pzhj 2628 5 were be VBD cord-005646-xhx9pzhj 2628 6 of of IN cord-005646-xhx9pzhj 2628 7 sepsis sepsis NN cord-005646-xhx9pzhj 2628 8 ( ( -LRB- cord-005646-xhx9pzhj 2628 9 36.2 36.2 CD cord-005646-xhx9pzhj 2628 10 % % NN cord-005646-xhx9pzhj 2628 11 ) ) -RRB- cord-005646-xhx9pzhj 2628 12 , , , cord-005646-xhx9pzhj 2628 13 CNS CNS NNP cord-005646-xhx9pzhj 2628 14 disorder disorder NN cord-005646-xhx9pzhj 2628 15 ( ( -LRB- cord-005646-xhx9pzhj 2628 16 22,2 22,2 CD cord-005646-xhx9pzhj 2628 17 % % NN cord-005646-xhx9pzhj 2628 18 ) ) -RRB- cord-005646-xhx9pzhj 2628 19 followed follow VBN cord-005646-xhx9pzhj 2628 20 by by IN cord-005646-xhx9pzhj 2628 21 respiratory respiratory JJ cord-005646-xhx9pzhj 2628 22 problems problem NNS cord-005646-xhx9pzhj 2628 23 ( ( -LRB- cord-005646-xhx9pzhj 2628 24 14.6 14.6 CD cord-005646-xhx9pzhj 2628 25 % % NN cord-005646-xhx9pzhj 2628 26 ) ) -RRB- cord-005646-xhx9pzhj 2628 27 . . . cord-005646-xhx9pzhj 2629 1 It -PRON- PRP cord-005646-xhx9pzhj 2629 2 seems seem VBZ cord-005646-xhx9pzhj 2629 3 therefore therefore RB cord-005646-xhx9pzhj 2629 4 that that IN cord-005646-xhx9pzhj 2629 5 the the DT cord-005646-xhx9pzhj 2629 6 major major JJ cord-005646-xhx9pzhj 2629 7 indicatiou indicatiou NN cord-005646-xhx9pzhj 2629 8 for for IN cord-005646-xhx9pzhj 2629 9 ventilation ventilation NN cord-005646-xhx9pzhj 2629 10 was be VBD cord-005646-xhx9pzhj 2629 11 overwhelming overwhelming JJ cord-005646-xhx9pzhj 2629 12 septicemia septicemia NN cord-005646-xhx9pzhj 2629 13 leading lead VBG cord-005646-xhx9pzhj 2629 14 to to IN cord-005646-xhx9pzhj 2629 15 multiple multiple JJ cord-005646-xhx9pzhj 2629 16 organ organ NN cord-005646-xhx9pzhj 2629 17 failure failure NN cord-005646-xhx9pzhj 2629 18 , , , cord-005646-xhx9pzhj 2629 19 rather rather RB cord-005646-xhx9pzhj 2629 20 than than IN cord-005646-xhx9pzhj 2629 21 purely purely RB cord-005646-xhx9pzhj 2629 22 respiratory respiratory JJ cord-005646-xhx9pzhj 2629 23 problems problem NNS cord-005646-xhx9pzhj 2629 24 . . . cord-005646-xhx9pzhj 2630 1 High high JJ cord-005646-xhx9pzhj 2630 2 frequency frequency NN cord-005646-xhx9pzhj 2630 3 oscillation oscillation NN cord-005646-xhx9pzhj 2630 4 ( ( -LRB- cord-005646-xhx9pzhj 2630 5 HFO HFO NNP cord-005646-xhx9pzhj 2630 6 ) ) -RRB- cord-005646-xhx9pzhj 2630 7 in in IN cord-005646-xhx9pzhj 2630 8 the the DT cord-005646-xhx9pzhj 2630 9 therapy therapy NN cord-005646-xhx9pzhj 2630 10 for for IN cord-005646-xhx9pzhj 2630 11 ARDS ARDS NNP cord-005646-xhx9pzhj 2630 12 in in IN cord-005646-xhx9pzhj 2630 13 pediatric pediatric JJ cord-005646-xhx9pzhj 2630 14 patients patient NNS cord-005646-xhx9pzhj 2630 15 requiring require VBG cord-005646-xhx9pzhj 2630 16 aggressive aggressive JJ cord-005646-xhx9pzhj 2630 17 conventional conventional JJ cord-005646-xhx9pzhj 2630 18 mechanical mechanical JJ cord-005646-xhx9pzhj 2630 19 ventilation ventilation NN cord-005646-xhx9pzhj 2630 20 ( ( -LRB- cord-005646-xhx9pzhj 2630 21 CMV CMV NNP cord-005646-xhx9pzhj 2630 22 ) ) -RRB- cord-005646-xhx9pzhj 2630 23 -routine -routine NN cord-005646-xhx9pzhj 2630 24 or or CC cord-005646-xhx9pzhj 2630 25 experimental experimental JJ cord-005646-xhx9pzhj 2630 26 mode mode NN cord-005646-xhx9pzhj 2630 27 ef ef NNP cord-005646-xhx9pzhj 2630 28 pre pre JJ cord-005646-xhx9pzhj 2630 29 ECMO ECMO NNP cord-005646-xhx9pzhj 2630 30 therapy therapy NN cord-005646-xhx9pzhj 2630 31 . . . cord-005646-xhx9pzhj 2631 1 Fedora Fedora NNP cord-005646-xhx9pzhj 2631 2 M. M. NNP cord-005646-xhx9pzhj 2631 3 , , , cord-005646-xhx9pzhj 2631 4 Nekvasi~ Nekvasi~ NNP cord-005646-xhx9pzhj 2631 5 R r NN cord-005646-xhx9pzhj 2631 6 , , , cord-005646-xhx9pzhj 2631 7 Vobruba Vobruba NNP cord-005646-xhx9pzhj 2631 8 V. V. NNP cord-005646-xhx9pzhj 2631 9 , , , cord-005646-xhx9pzhj 2631 10 Srnsky Srnsky NNP cord-005646-xhx9pzhj 2631 11 P P NNP cord-005646-xhx9pzhj 2631 12 , , , cord-005646-xhx9pzhj 2631 13 , , , cord-005646-xhx9pzhj 2631 14 Zapadlo Zapadlo NNP cord-005646-xhx9pzhj 2631 15 M. M. NNP cord-005646-xhx9pzhj 2631 16 Dpt Dpt NNP cord-005646-xhx9pzhj 2631 17 . . . cord-005646-xhx9pzhj 2632 1 Critical Critical NNP cord-005646-xhx9pzhj 2632 2 Care Care NNP cord-005646-xhx9pzhj 2632 3 Medicine Medicine NNP cord-005646-xhx9pzhj 2632 4 , , , cord-005646-xhx9pzhj 2632 5 NICU NICU NNP cord-005646-xhx9pzhj 2632 6 and and CC cord-005646-xhx9pzhj 2632 7 ECMO ECMO NNP cord-005646-xhx9pzhj 2632 8 Center Center NNP cord-005646-xhx9pzhj 2632 9 , , , cord-005646-xhx9pzhj 2632 10 University University NNP cord-005646-xhx9pzhj 2632 11 Children Children NNPS cord-005646-xhx9pzhj 2632 12 's 's POS cord-005646-xhx9pzhj 2632 13 Hospita Hospita NNP cord-005646-xhx9pzhj 2632 14 ! ! . cord-005646-xhx9pzhj 2633 1 Brne Brne NNP cord-005646-xhx9pzhj 2633 2 , , , cord-005646-xhx9pzhj 2633 3 NICU NICU NNP cord-005646-xhx9pzhj 2633 4 of of IN cord-005646-xhx9pzhj 2633 5 University University NNP cord-005646-xhx9pzhj 2633 6 Hospital Hospital NNP cord-005646-xhx9pzhj 2633 7 Prague Prague NNP cord-005646-xhx9pzhj 2633 8 , , , cord-005646-xhx9pzhj 2633 9 Czech Czech NNP cord-005646-xhx9pzhj 2633 10 Republic Republic NNP cord-005646-xhx9pzhj 2633 11 . . . cord-005646-xhx9pzhj 2634 1 Introduction introduction NN cord-005646-xhx9pzhj 2634 2 : : : cord-005646-xhx9pzhj 2634 3 9 9 CD cord-005646-xhx9pzhj 2634 4 pediatric pediatric JJ cord-005646-xhx9pzhj 2634 5 patients patient NNS cord-005646-xhx9pzhj 2634 6 ( ( -LRB- cord-005646-xhx9pzhj 2634 7 8 8 CD cord-005646-xhx9pzhj 2634 8 males male NNS cord-005646-xhx9pzhj 2634 9 , , , cord-005646-xhx9pzhj 2634 10 1 1 CD cord-005646-xhx9pzhj 2634 11 female female JJ cord-005646-xhx9pzhj 2634 12 , , , cord-005646-xhx9pzhj 2634 13 average average JJ cord-005646-xhx9pzhj 2634 14 age age NN cord-005646-xhx9pzhj 2634 15 4.7 4.7 CD cord-005646-xhx9pzhj 2634 16 months month NNS cord-005646-xhx9pzhj 2634 17 , , , cord-005646-xhx9pzhj 2634 18 average average JJ cord-005646-xhx9pzhj 2634 19 body body NN cord-005646-xhx9pzhj 2634 20 weight weight NN cord-005646-xhx9pzhj 2634 21 5,8 5,8 CD cord-005646-xhx9pzhj 2634 22 kg kg NNP cord-005646-xhx9pzhj 2634 23 ) ) -RRB- cord-005646-xhx9pzhj 2634 24 with with IN cord-005646-xhx9pzhj 2634 25 severe severe JJ cord-005646-xhx9pzhj 2634 26 ARDS ARDS NNP cord-005646-xhx9pzhj 2634 27 ventilated ventilate VBN cord-005646-xhx9pzhj 2634 28 with with IN cord-005646-xhx9pzhj 2634 29 aggressive aggressive JJ cord-005646-xhx9pzhj 2634 30 regimen regimen NN cord-005646-xhx9pzhj 2634 31 of of IN cord-005646-xhx9pzhj 2634 32 PCV PCV NNP cord-005646-xhx9pzhj 2634 33 or or CC cord-005646-xhx9pzhj 2634 34 PRVC PRVC NNP cord-005646-xhx9pzhj 2634 35 were be VBD cord-005646-xhx9pzhj 2634 36 connected connect VBN cord-005646-xhx9pzhj 2634 37 to to IN cord-005646-xhx9pzhj 2634 38 HFO HFO NNP cord-005646-xhx9pzhj 2634 39 ( ( -LRB- cord-005646-xhx9pzhj 2634 40 Sensormedics sensormedic NNS cord-005646-xhx9pzhj 2634 41 3100 3100 CD cord-005646-xhx9pzhj 2634 42 ) ) -RRB- cord-005646-xhx9pzhj 2634 43 as as IN cord-005646-xhx9pzhj 2634 44 the the DT cord-005646-xhx9pzhj 2634 45 last last JJ cord-005646-xhx9pzhj 2634 46 " " `` cord-005646-xhx9pzhj 2634 47 rescue rescue NN cord-005646-xhx9pzhj 2634 48 " " '' cord-005646-xhx9pzhj 2634 49 therapy therapy NN cord-005646-xhx9pzhj 2634 50 due due IN cord-005646-xhx9pzhj 2634 51 to to IN cord-005646-xhx9pzhj 2634 52 uncontrollable uncontrollable JJ cord-005646-xhx9pzhj 2634 53 respiratory respiratory JJ cord-005646-xhx9pzhj 2634 54 failure failure NN cord-005646-xhx9pzhj 2634 55 before before IN cord-005646-xhx9pzhj 2634 56 intended intend VBN cord-005646-xhx9pzhj 2634 57 ECMO ECMO NNP cord-005646-xhx9pzhj 2634 58 . . . cord-005646-xhx9pzhj 2635 1 In in IN cord-005646-xhx9pzhj 2635 2 the the DT cord-005646-xhx9pzhj 2635 3 course course NN cord-005646-xhx9pzhj 2635 4 of of IN cord-005646-xhx9pzhj 2635 5 HFO HFO NNP cord-005646-xhx9pzhj 2635 6 2 2 CD cord-005646-xhx9pzhj 2635 7 of of IN cord-005646-xhx9pzhj 2635 8 them -PRON- PRP cord-005646-xhx9pzhj 2635 9 were be VBD cord-005646-xhx9pzhj 2635 10 given give VBN cord-005646-xhx9pzhj 2635 11 NO no RB cord-005646-xhx9pzhj 2635 12 in in IN cord-005646-xhx9pzhj 2635 13 the the DT cord-005646-xhx9pzhj 2635 14 concentrations concentration NNS cord-005646-xhx9pzhj 2635 15 of of IN cord-005646-xhx9pzhj 2635 16 5 5 CD cord-005646-xhx9pzhj 2635 17 - - SYM cord-005646-xhx9pzhj 2635 18 80 80 CD cord-005646-xhx9pzhj 2635 19 p.p.m p.p.m NN cord-005646-xhx9pzhj 2635 20 . . NN cord-005646-xhx9pzhj 2635 21 , , , cord-005646-xhx9pzhj 2635 22 3 3 CD cord-005646-xhx9pzhj 2635 23 were be VBD cord-005646-xhx9pzhj 2635 24 subjected subject VBN cord-005646-xhx9pzhj 2635 25 repeatedly repeatedly RB cord-005646-xhx9pzhj 2635 26 to to IN cord-005646-xhx9pzhj 2635 27 surfactant surfactant NN cord-005646-xhx9pzhj 2635 28 replacement replacement NN cord-005646-xhx9pzhj 2635 29 therapy therapy NN cord-005646-xhx9pzhj 2635 30 ( ( -LRB- cord-005646-xhx9pzhj 2635 31 Alveofact Alveofact NNP cord-005646-xhx9pzhj 2635 32 ) ) -RRB- cord-005646-xhx9pzhj 2635 33 . . . cord-005646-xhx9pzhj 2636 1 Results result NNS cord-005646-xhx9pzhj 2636 2 : : : cord-005646-xhx9pzhj 2637 1 ECMO ECMO NNP cord-005646-xhx9pzhj 2637 2 was be VBD cord-005646-xhx9pzhj 2637 3 needed need VBN cord-005646-xhx9pzhj 2637 4 in in IN cord-005646-xhx9pzhj 2637 5 no no DT cord-005646-xhx9pzhj 2637 6 patient patient NN cord-005646-xhx9pzhj 2637 7 , , , cord-005646-xhx9pzhj 2637 8 8 8 CD cord-005646-xhx9pzhj 2637 9 patients patient NNS cord-005646-xhx9pzhj 2637 10 survived survive VBD cord-005646-xhx9pzhj 2637 11 , , , cord-005646-xhx9pzhj 2637 12 1 1 CD cord-005646-xhx9pzhj 2637 13 patient patient NN cord-005646-xhx9pzhj 2637 14 was be VBD cord-005646-xhx9pzhj 2637 15 disconnected disconnect VBN cord-005646-xhx9pzhj 2637 16 from from IN cord-005646-xhx9pzhj 2637 17 the the DT cord-005646-xhx9pzhj 2637 18 ventilator ventilator NN cord-005646-xhx9pzhj 2637 19 because because IN cord-005646-xhx9pzhj 2637 20 of of IN cord-005646-xhx9pzhj 2637 21 brain brain NN cord-005646-xhx9pzhj 2637 22 death death NN cord-005646-xhx9pzhj 2637 23 in in IN cord-005646-xhx9pzhj 2637 24 spite spite NN cord-005646-xhx9pzhj 2637 25 of of IN cord-005646-xhx9pzhj 2637 26 conspicuous conspicuous JJ cord-005646-xhx9pzhj 2637 27 improvement improvement NN cord-005646-xhx9pzhj 2637 28 of of IN cord-005646-xhx9pzhj 2637 29 oxygenation oxygenation NN cord-005646-xhx9pzhj 2637 30 and and CC cord-005646-xhx9pzhj 2637 31 other other JJ cord-005646-xhx9pzhj 2637 32 parameters parameter NNS cord-005646-xhx9pzhj 2637 33 , , , cord-005646-xhx9pzhj 2637 34 Some some DT cord-005646-xhx9pzhj 2637 35 relevant relevant JJ cord-005646-xhx9pzhj 2637 36 parameters parameter NNS cord-005646-xhx9pzhj 2637 37 48 48 CD cord-005646-xhx9pzhj 2637 38 hours hour NNS cord-005646-xhx9pzhj 2637 39 before before RB cord-005646-xhx9pzhj 2637 40 and and CC cord-005646-xhx9pzhj 2637 41 48 48 CD cord-005646-xhx9pzhj 2637 42 hours hour NNS cord-005646-xhx9pzhj 2637 43 after after IN cord-005646-xhx9pzhj 2637 44 starting start VBG cord-005646-xhx9pzhj 2637 45 HFO HFO NNP cord-005646-xhx9pzhj 2637 46 are be VBP cord-005646-xhx9pzhj 2637 47 given give VBN cord-005646-xhx9pzhj 2637 48 in in IN cord-005646-xhx9pzhj 2637 49 table table NN cord-005646-xhx9pzhj 2637 50 1~ 1~ CD cord-005646-xhx9pzhj 2638 1 In in IN cord-005646-xhx9pzhj 2638 2 all all PDT cord-005646-xhx9pzhj 2638 3 the the DT cord-005646-xhx9pzhj 2638 4 cases case NNS cord-005646-xhx9pzhj 2638 5 , , , cord-005646-xhx9pzhj 2638 6 the the DT cord-005646-xhx9pzhj 2638 7 disconnection disconnection NN cord-005646-xhx9pzhj 2638 8 from from IN cord-005646-xhx9pzhj 2638 9 HFO HFO NNP cord-005646-xhx9pzhj 2638 10 was be VBD cord-005646-xhx9pzhj 2638 11 carried carry VBN cord-005646-xhx9pzhj 2638 12 out out RP cord-005646-xhx9pzhj 2638 13 through through IN cord-005646-xhx9pzhj 2638 14 the the DT cord-005646-xhx9pzhj 2638 15 SIMV SIMV NNP cord-005646-xhx9pzhj 2638 16 regimen regimen NN cord-005646-xhx9pzhj 2638 17 , , , cord-005646-xhx9pzhj 2638 18 never never RB cord-005646-xhx9pzhj 2638 19 directly directly RB cord-005646-xhx9pzhj 2638 20 to to IN cord-005646-xhx9pzhj 2638 21 CPAP CPAP NNP cord-005646-xhx9pzhj 2638 22 . . . cord-005646-xhx9pzhj 2639 1 Table table NN cord-005646-xhx9pzhj 2639 2 1 1 CD cord-005646-xhx9pzhj 2639 3 : : : cord-005646-xhx9pzhj 2640 1 The the DT cord-005646-xhx9pzhj 2640 2 levels level NNS cord-005646-xhx9pzhj 2640 3 of of IN cord-005646-xhx9pzhj 2640 4 blood blood NN cord-005646-xhx9pzhj 2640 5 gases gas NNS cord-005646-xhx9pzhj 2640 6 , , , cord-005646-xhx9pzhj 2640 7 oxygenation oxygenation NN cord-005646-xhx9pzhj 2640 8 index index NN cord-005646-xhx9pzhj 2640 9 ( ( -LRB- cord-005646-xhx9pzhj 2640 10 OI OI NNP cord-005646-xhx9pzhj 2640 11 ) ) -RRB- cord-005646-xhx9pzhj 2640 12 , , , cord-005646-xhx9pzhj 2640 13 AaDO2,MAP aado2,map JJ cord-005646-xhx9pzhj 2640 14 , , , cord-005646-xhx9pzhj 2640 15 FiO2 FiO2 NNS cord-005646-xhx9pzhj 2640 16 and and CC cord-005646-xhx9pzhj 2640 17 PaO2 PaO2 NNS cord-005646-xhx9pzhj 2640 18 / / SYM cord-005646-xhx9pzhj 2640 19 FiO2 FiO2 NNS cord-005646-xhx9pzhj 2640 20 ratio ratio NN cord-005646-xhx9pzhj 2640 21 48 48 CD cord-005646-xhx9pzhj 2640 22 hours hour NNS cord-005646-xhx9pzhj 2640 23 before before RB cord-005646-xhx9pzhj 2640 24 and and CC cord-005646-xhx9pzhj 2640 25 48 48 CD cord-005646-xhx9pzhj 2640 26 hours hour NNS cord-005646-xhx9pzhj 2640 27 after after IN cord-005646-xhx9pzhj 2640 28 starting start VBG cord-005646-xhx9pzhj 2640 29 HFO HFO NNP cord-005646-xhx9pzhj 2640 30 . . . cord-005646-xhx9pzhj 2641 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2641 2 : : : cord-005646-xhx9pzhj 2642 1 Although although IN cord-005646-xhx9pzhj 2642 2 none none NN cord-005646-xhx9pzhj 2642 3 of of IN cord-005646-xhx9pzhj 2642 4 the the DT cord-005646-xhx9pzhj 2642 5 patient patient NN cord-005646-xhx9pzhj 2642 6 had have VBD cord-005646-xhx9pzhj 2642 7 to to TO cord-005646-xhx9pzhj 2642 8 be be VB cord-005646-xhx9pzhj 2642 9 subjected subject VBN cord-005646-xhx9pzhj 2642 10 to to IN cord-005646-xhx9pzhj 2642 11 pediatric pediatric JJ cord-005646-xhx9pzhj 2642 12 ECMO ECMO NNP cord-005646-xhx9pzhj 2642 13 , , , cord-005646-xhx9pzhj 2642 14 HFO HFO NNP cord-005646-xhx9pzhj 2642 15 should should MD cord-005646-xhx9pzhj 2642 16 be be VB cord-005646-xhx9pzhj 2642 17 carried carry VBN cord-005646-xhx9pzhj 2642 18 out out RP cord-005646-xhx9pzhj 2642 19 only only RB cord-005646-xhx9pzhj 2642 20 in in IN cord-005646-xhx9pzhj 2642 21 workplaces workplace NNS cord-005646-xhx9pzhj 2642 22 having have VBG cord-005646-xhx9pzhj 2642 23 the the DT cord-005646-xhx9pzhj 2642 24 immediate immediate JJ cord-005646-xhx9pzhj 2642 25 possibility possibility NN cord-005646-xhx9pzhj 2642 26 of of IN cord-005646-xhx9pzhj 2642 27 using use VBG cord-005646-xhx9pzhj 2642 28 this this DT cord-005646-xhx9pzhj 2642 29 method method NN cord-005646-xhx9pzhj 2642 30 in in IN cord-005646-xhx9pzhj 2642 31 the the DT cord-005646-xhx9pzhj 2642 32 case case NN cord-005646-xhx9pzhj 2642 33 of of IN cord-005646-xhx9pzhj 2642 34 HFO HFO NNP cord-005646-xhx9pzhj 2642 35 failure failure NN cord-005646-xhx9pzhj 2642 36 . . . cord-005646-xhx9pzhj 2643 1 Speculation speculation NN cord-005646-xhx9pzhj 2643 2 : : : cord-005646-xhx9pzhj 2643 3 Should Should MD cord-005646-xhx9pzhj 2643 4 not not RB cord-005646-xhx9pzhj 2643 5 HFO HFO NNP cord-005646-xhx9pzhj 2643 6 be be VB cord-005646-xhx9pzhj 2643 7 used use VBN cord-005646-xhx9pzhj 2643 8 ir ir NNP cord-005646-xhx9pzhj 2643 9 pediatric pediatric JJ cord-005646-xhx9pzhj 2643 10 patients patient NNS cord-005646-xhx9pzhj 2643 11 with with IN cord-005646-xhx9pzhj 2643 12 ARDS ARDS NNP cord-005646-xhx9pzhj 2643 13 earlier early RBR cord-005646-xhx9pzhj 2643 14 than than IN cord-005646-xhx9pzhj 2643 15 aggressive aggressive JJ cord-005646-xhx9pzhj 2643 16 CMV CMV NNP cord-005646-xhx9pzhj 2643 17 ? ? . cord-005646-xhx9pzhj 2644 1 Can Can MD cord-005646-xhx9pzhj 2644 2 HFO HFO NNP cord-005646-xhx9pzhj 2644 3 ce ce NNP cord-005646-xhx9pzhj 2644 4 considered consider VBN cord-005646-xhx9pzhj 2644 5 standard standard NN cord-005646-xhx9pzhj 2644 6 , , , cord-005646-xhx9pzhj 2644 7 not not RB cord-005646-xhx9pzhj 2644 8 experimental experimental JJ cord-005646-xhx9pzhj 2644 9 method method NN cord-005646-xhx9pzhj 2644 10 of of IN cord-005646-xhx9pzhj 2644 11 therapy therapy NN cord-005646-xhx9pzhj 2644 12 ? ? . cord-005646-xhx9pzhj 2645 1 Refractory refractory JJ cord-005646-xhx9pzhj 2645 2 hypoxemia hypoxemia NN cord-005646-xhx9pzhj 2645 3 in in IN cord-005646-xhx9pzhj 2645 4 premature premature JJ cord-005646-xhx9pzhj 2645 5 patients patient NNS cord-005646-xhx9pzhj 2645 6 is be VBZ cord-005646-xhx9pzhj 2645 7 characterized characterize VBN cord-005646-xhx9pzhj 2645 8 in in IN cord-005646-xhx9pzhj 2645 9 a a DT cord-005646-xhx9pzhj 2645 10 persistent persistent JJ cord-005646-xhx9pzhj 2645 11 elevation elevation NN cord-005646-xhx9pzhj 2645 12 of of IN cord-005646-xhx9pzhj 2645 13 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2645 14 vascular vascular JJ cord-005646-xhx9pzhj 2645 15 resistance resistance NN cord-005646-xhx9pzhj 2645 16 , , , cord-005646-xhx9pzhj 2645 17 with with IN cord-005646-xhx9pzhj 2645 18 right right NN cord-005646-xhx9pzhj 2645 19 to to IN cord-005646-xhx9pzhj 2645 20 left left JJ cord-005646-xhx9pzhj 2645 21 shunt shunt NN cord-005646-xhx9pzhj 2645 22 through through IN cord-005646-xhx9pzhj 2645 23 the the DT cord-005646-xhx9pzhj 2645 24 ductus ductus NN cord-005646-xhx9pzhj 2645 25 arteriosus arteriosus NN cord-005646-xhx9pzhj 2645 26 and and CC cord-005646-xhx9pzhj 2645 27 or or CC cord-005646-xhx9pzhj 2645 28 foramen foramen NN cord-005646-xhx9pzhj 2645 29 oval oval NN cord-005646-xhx9pzhj 2645 30 . . . cord-005646-xhx9pzhj 2646 1 We -PRON- PRP cord-005646-xhx9pzhj 2646 2 report report VBP cord-005646-xhx9pzhj 2646 3 the the DT cord-005646-xhx9pzhj 2646 4 case case NN cord-005646-xhx9pzhj 2646 5 of of IN cord-005646-xhx9pzhj 2646 6 a a DT cord-005646-xhx9pzhj 2646 7 VLBW VLBW NNP cord-005646-xhx9pzhj 2646 8 patient patient NN cord-005646-xhx9pzhj 2646 9 ( ( -LRB- cord-005646-xhx9pzhj 2646 10 GA GA NNP cord-005646-xhx9pzhj 2646 11 27W 27W NNP cord-005646-xhx9pzhj 2646 12 , , , cord-005646-xhx9pzhj 2646 13 BW BW NNP cord-005646-xhx9pzhj 2646 14 1010 1010 CD cord-005646-xhx9pzhj 2646 15 g g NNP cord-005646-xhx9pzhj 2646 16 ) ) -RRB- cord-005646-xhx9pzhj 2646 17 who who WP cord-005646-xhx9pzhj 2646 18 present present VBP cord-005646-xhx9pzhj 2646 19 a a DT cord-005646-xhx9pzhj 2646 20 severe severe JJ cord-005646-xhx9pzhj 2646 21 hypoxemia hypoxemia NN cord-005646-xhx9pzhj 2646 22 related relate VBN cord-005646-xhx9pzhj 2646 23 to to IN cord-005646-xhx9pzhj 2646 24 hyaline hyaline JJ cord-005646-xhx9pzhj 2646 25 membrane membrane NN cord-005646-xhx9pzhj 2646 26 disease disease NN cord-005646-xhx9pzhj 2646 27 and and CC cord-005646-xhx9pzhj 2646 28 a a DT cord-005646-xhx9pzhj 2646 29 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2646 30 and and CC cord-005646-xhx9pzhj 2646 31 systemic systemic JJ cord-005646-xhx9pzhj 2646 32 infection infection NN cord-005646-xhx9pzhj 2646 33 to to IN cord-005646-xhx9pzhj 2646 34 group group NN cord-005646-xhx9pzhj 2646 35 B b NN cord-005646-xhx9pzhj 2646 36 streptococcus streptococcus NN cord-005646-xhx9pzhj 2646 37 , , , cord-005646-xhx9pzhj 2646 38 refractory refractory JJ cord-005646-xhx9pzhj 2646 39 to to IN cord-005646-xhx9pzhj 2646 40 conventional conventional JJ cord-005646-xhx9pzhj 2646 41 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2646 42 support support NN cord-005646-xhx9pzhj 2646 43 and and CC cord-005646-xhx9pzhj 2646 44 surfactant surfactant NN cord-005646-xhx9pzhj 2646 45 therapy therapy NN cord-005646-xhx9pzhj 2646 46 , , , cord-005646-xhx9pzhj 2646 47 associated associate VBN cord-005646-xhx9pzhj 2646 48 to to IN cord-005646-xhx9pzhj 2646 49 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 2646 50 failure failure NN cord-005646-xhx9pzhj 2646 51 falling fall VBG cord-005646-xhx9pzhj 2646 52 in in IN cord-005646-xhx9pzhj 2646 53 ECMO ECMO NNP cord-005646-xhx9pzhj 2646 54 criteria criterion NNS cord-005646-xhx9pzhj 2646 55 used use VBN cord-005646-xhx9pzhj 2646 56 for for IN cord-005646-xhx9pzhj 2646 57 term term NN cord-005646-xhx9pzhj 2646 58 infants infant NNS cord-005646-xhx9pzhj 2646 59 . . . cord-005646-xhx9pzhj 2647 1 A a DT cord-005646-xhx9pzhj 2647 2 rescue rescue NN cord-005646-xhx9pzhj 2647 3 therapy therapy NN cord-005646-xhx9pzhj 2647 4 with with IN cord-005646-xhx9pzhj 2647 5 HFOV HFOV NNP cord-005646-xhx9pzhj 2648 1 ( ( -LRB- cord-005646-xhx9pzhj 2648 2 Sensor Sensor NNP cord-005646-xhx9pzhj 2648 3 Medics Medics NNPS cord-005646-xhx9pzhj 2648 4 3100A 3100a CD cord-005646-xhx9pzhj 2648 5 ) ) -RRB- cord-005646-xhx9pzhj 2648 6 is be VBZ cord-005646-xhx9pzhj 2648 7 decided decide VBN cord-005646-xhx9pzhj 2648 8 at at IN cord-005646-xhx9pzhj 2648 9 5 5 CD cord-005646-xhx9pzhj 2648 10 h h NN cord-005646-xhx9pzhj 2648 11 of of IN cord-005646-xhx9pzhj 2648 12 live live NN cord-005646-xhx9pzhj 2648 13 , , , cord-005646-xhx9pzhj 2648 14 The the DT cord-005646-xhx9pzhj 2648 15 table table NN cord-005646-xhx9pzhj 2648 16 resume resume VBP cord-005646-xhx9pzhj 2648 17 the the DT cord-005646-xhx9pzhj 2648 18 patient patient NN cord-005646-xhx9pzhj 2648 19 's 's POS cord-005646-xhx9pzhj 2648 20 evolution evolution NN cord-005646-xhx9pzhj 2648 21 before before RB cord-005646-xhx9pzhj 2648 22 and and CC cord-005646-xhx9pzhj 2648 23 after after IN cord-005646-xhx9pzhj 2648 24 HFOV HFOV NNP cord-005646-xhx9pzhj 2648 25 . . . cord-005646-xhx9pzhj 2649 1 At at IN cord-005646-xhx9pzhj 2649 2 36W 36w CD cord-005646-xhx9pzhj 2649 3 of of IN cord-005646-xhx9pzhj 2649 4 postgestational postgestational NNP cord-005646-xhx9pzhj 2649 5 age age NN cord-005646-xhx9pzhj 2649 6 the the DT cord-005646-xhx9pzhj 2649 7 patient patient NN cord-005646-xhx9pzhj 2649 8 present present VBP cord-005646-xhx9pzhj 2649 9 a a DT cord-005646-xhx9pzhj 2649 10 FiO2 FiO2 NNS cord-005646-xhx9pzhj 2649 11 of of IN cord-005646-xhx9pzhj 2649 12 0.23 0.23 CD cord-005646-xhx9pzhj 2649 13 with with IN cord-005646-xhx9pzhj 2649 14 a a DT cord-005646-xhx9pzhj 2649 15 chest chest NN cord-005646-xhx9pzhj 2649 16 X x NN cord-005646-xhx9pzhj 2649 17 ray ray NN cord-005646-xhx9pzhj 2649 18 compatible compatible JJ cord-005646-xhx9pzhj 2649 19 with with IN cord-005646-xhx9pzhj 2649 20 a a DT cord-005646-xhx9pzhj 2649 21 CLD CLD NNP cord-005646-xhx9pzhj 2649 22 type type NN cord-005646-xhx9pzhj 2649 23 L l NN cord-005646-xhx9pzhj 2650 1 At at IN cord-005646-xhx9pzhj 2650 2 discharge discharge NN cord-005646-xhx9pzhj 2650 3 no no DT cord-005646-xhx9pzhj 2650 4 oxygen oxygen NN cord-005646-xhx9pzhj 2650 5 requirements requirement NNS cord-005646-xhx9pzhj 2650 6 was be VBD cord-005646-xhx9pzhj 2650 7 needed need VBN cord-005646-xhx9pzhj 2650 8 and and CC cord-005646-xhx9pzhj 2650 9 actually actually RB cord-005646-xhx9pzhj 2650 10 he -PRON- PRP cord-005646-xhx9pzhj 2650 11 's be VBZ cord-005646-xhx9pzhj 2650 12 doing do VBG cord-005646-xhx9pzhj 2650 13 well well RB cord-005646-xhx9pzhj 2650 14 . . . cord-005646-xhx9pzhj 2651 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 2651 2 : : : cord-005646-xhx9pzhj 2651 3 HFOV HFOV NNP cord-005646-xhx9pzhj 2651 4 , , , cord-005646-xhx9pzhj 2652 1 using use VBG cord-005646-xhx9pzhj 2652 2 an an DT cord-005646-xhx9pzhj 2652 3 adequate adequate JJ cord-005646-xhx9pzhj 2652 4 alveolar alveolar NN cord-005646-xhx9pzhj 2652 5 recruitment recruitment NN cord-005646-xhx9pzhj 2652 6 strategy strategy NN cord-005646-xhx9pzhj 2652 7 , , , cord-005646-xhx9pzhj 2652 8 was be VBD cord-005646-xhx9pzhj 2652 9 effective effective JJ cord-005646-xhx9pzhj 2652 10 in in IN cord-005646-xhx9pzhj 2652 11 the the DT cord-005646-xhx9pzhj 2652 12 rescue rescue NN cord-005646-xhx9pzhj 2652 13 of of IN cord-005646-xhx9pzhj 2652 14 a a DT cord-005646-xhx9pzhj 2652 15 severe severe JJ cord-005646-xhx9pzhj 2652 16 hypoxemic hypoxemic JJ cord-005646-xhx9pzhj 2652 17 respiratory respiratory JJ cord-005646-xhx9pzhj 2652 18 failure failure NN cord-005646-xhx9pzhj 2652 19 with with IN cord-005646-xhx9pzhj 2652 20 a a DT cord-005646-xhx9pzhj 2652 21 rapid rapid JJ cord-005646-xhx9pzhj 2652 22 off off IN cord-005646-xhx9pzhj 2652 23 of of IN cord-005646-xhx9pzhj 2652 24 ECMO ECMO NNP cord-005646-xhx9pzhj 2652 25 criteria criterion NNS cord-005646-xhx9pzhj 2652 26 entry entry NN cord-005646-xhx9pzhj 2652 27 in in IN cord-005646-xhx9pzhj 2652 28 our -PRON- PRP$ cord-005646-xhx9pzhj 2652 29 VLBW VLBW NNP cord-005646-xhx9pzhj 2652 30 premature premature JJ cord-005646-xhx9pzhj 2652 31 patient patient NN cord-005646-xhx9pzhj 2652 32 , , , cord-005646-xhx9pzhj 2652 33 During during IN cord-005646-xhx9pzhj 2652 34 the the DT cord-005646-xhx9pzhj 2652 35 United United NNP cord-005646-xhx9pzhj 2652 36 Nmioffs Nmioffs NNP cord-005646-xhx9pzhj 2652 37 embargo embargo NN cord-005646-xhx9pzhj 2652 38 ~nst ~nst NNP cord-005646-xhx9pzhj 2653 1 Yugoslavia Yugoslavia NNP cord-005646-xhx9pzhj 2653 2 the the DT cord-005646-xhx9pzhj 2653 3 prevalence prevalence NN cord-005646-xhx9pzhj 2653 4 of of IN cord-005646-xhx9pzhj 2653 5 the the DT cord-005646-xhx9pzhj 2653 6 ast}nnafic ast}nnafic NNP cord-005646-xhx9pzhj 2653 7 ~acks ~acks NNP cord-005646-xhx9pzhj 2653 8 in in IN cord-005646-xhx9pzhj 2653 9 c c NN cord-005646-xhx9pzhj 2654 1 ~dldren ~dldren NNP cord-005646-xhx9pzhj 2654 2 aratsed aratse VBD cord-005646-xhx9pzhj 2654 3 . . . cord-005646-xhx9pzhj 2655 1 The the DT cord-005646-xhx9pzhj 2655 2 mo mo NNP cord-005646-xhx9pzhj 2655 3 ~ ~ NFP cord-005646-xhx9pzhj 2655 4 t t XX cord-005646-xhx9pzhj 2655 5 common common JJ cord-005646-xhx9pzhj 2655 6 causes cause NNS cord-005646-xhx9pzhj 2655 7 have have VBP cord-005646-xhx9pzhj 2655 8 beem beem VBN cord-005646-xhx9pzhj 2655 9 dramm dramm NNP cord-005646-xhx9pzhj 2655 10 ~ ~ NFP cord-005646-xhx9pzhj 2655 11 e e LS cord-005646-xhx9pzhj 2655 12 worsening worsening NN cord-005646-xhx9pzhj 2655 13 of of IN cord-005646-xhx9pzhj 2655 14 life life NN cord-005646-xhx9pzhj 2655 15 standard standard NN cord-005646-xhx9pzhj 2655 16 , , , cord-005646-xhx9pzhj 2655 17 ecom ecom NNP cord-005646-xhx9pzhj 2655 18 ~ ~ NFP cord-005646-xhx9pzhj 2655 19 c c NNP cord-005646-xhx9pzhj 2655 20 disaster disaster NN cord-005646-xhx9pzhj 2655 21 in in IN cord-005646-xhx9pzhj 2655 22 global global JJ cord-005646-xhx9pzhj 2655 23 community community NN cord-005646-xhx9pzhj 2655 24 , , , cord-005646-xhx9pzhj 2655 25 gr~ gr~ NN cord-005646-xhx9pzhj 2655 26 number number NN cord-005646-xhx9pzhj 2655 27 of of IN cord-005646-xhx9pzhj 2655 28 refugees refugee NNS cord-005646-xhx9pzhj 2655 29 from from IN cord-005646-xhx9pzhj 2655 30 the the DT cord-005646-xhx9pzhj 2655 31 other other JJ cord-005646-xhx9pzhj 2655 32 parts part NNS cord-005646-xhx9pzhj 2655 33 of of IN cord-005646-xhx9pzhj 2655 34 former former JJ cord-005646-xhx9pzhj 2655 35 Yugodavia Yugodavia NNP cord-005646-xhx9pzhj 2655 36 . . . cord-005646-xhx9pzhj 2656 1 It -PRON- PRP cord-005646-xhx9pzhj 2657 1 wm wm NNP cord-005646-xhx9pzhj 2657 2 obviom obviom NNP cord-005646-xhx9pzhj 2657 3 that that IN cord-005646-xhx9pzhj 2657 4 mcio mcio NNP cord-005646-xhx9pzhj 2657 5 - - HYPH cord-005646-xhx9pzhj 2657 6 ecoumnical ecoumnical JJ cord-005646-xhx9pzhj 2657 7 conditions condition NNS cord-005646-xhx9pzhj 2657 8 took take VBD cord-005646-xhx9pzhj 2657 9 a a DT cord-005646-xhx9pzhj 2657 10 part part NN cord-005646-xhx9pzhj 2657 11 in in IN cord-005646-xhx9pzhj 2657 12 the the DT cord-005646-xhx9pzhj 2657 13 exacerbations exacerbation NNS cord-005646-xhx9pzhj 2657 14 of of IN cord-005646-xhx9pzhj 2657 15 previously previously RB cord-005646-xhx9pzhj 2657 16 known know VBN cord-005646-xhx9pzhj 2657 17 cldldhood cldldhood NN cord-005646-xhx9pzhj 2657 18 asthra~ asthra~ NNP cord-005646-xhx9pzhj 2657 19 , , , cord-005646-xhx9pzhj 2658 1 ~av~ ~av~ NFP cord-005646-xhx9pzhj 2658 2 of of IN cord-005646-xhx9pzhj 2658 3 micro micro NNP cord-005646-xhx9pzhj 2658 4 - - : cord-005646-xhx9pzhj 2658 5 and and CC cord-005646-xhx9pzhj 2658 6 m m NNP cord-005646-xhx9pzhj 2658 7 ~ ~ NNP cord-005646-xhx9pzhj 2658 8 mclimaflc mclimaflc NNP cord-005646-xhx9pzhj 2658 9 changes change NNS cord-005646-xhx9pzhj 2658 10 , , , cord-005646-xhx9pzhj 2658 11 psychosocis psychosocis NNP cord-005646-xhx9pzhj 2658 12 ] ] -RRB- cord-005646-xhx9pzhj 2658 13 and and CC cord-005646-xhx9pzhj 2658 14 emotional emotional JJ cord-005646-xhx9pzhj 2658 15 cryses cryse NNS cord-005646-xhx9pzhj 2658 16 , , , cord-005646-xhx9pzhj 2659 1 lack lack NN cord-005646-xhx9pzhj 2659 2 of of IN cord-005646-xhx9pzhj 2659 3 medics medic NNS cord-005646-xhx9pzhj 2659 4 - - HYPH cord-005646-xhx9pzhj 2659 5 m m NNP cord-005646-xhx9pzhj 2659 6 ~ ~ NFP cord-005646-xhx9pzhj 2659 7 nts nt NNS cord-005646-xhx9pzhj 2659 8 for for IN cord-005646-xhx9pzhj 2659 9 p p NN cord-005646-xhx9pzhj 2659 10 ~ ~ NFP cord-005646-xhx9pzhj 2659 11 ve ve NNP cord-005646-xhx9pzhj 2659 12 ~ ~ NFP cord-005646-xhx9pzhj 2659 13 on on RB cord-005646-xhx9pzhj 2659 14 and and CC cord-005646-xhx9pzhj 2659 15 tl tl NNP cord-005646-xhx9pzhj 2659 16 ~ ~ NNP cord-005646-xhx9pzhj 2659 17 rspy rspy NNP cord-005646-xhx9pzhj 2659 18 of of IN cord-005646-xhx9pzhj 2659 19 acute acute JJ cord-005646-xhx9pzhj 2659 20 asflanatic asflanatic JJ cord-005646-xhx9pzhj 2659 21 attacks attack NNS cord-005646-xhx9pzhj 2659 22 . . . cord-005646-xhx9pzhj 2660 1 About about RB cord-005646-xhx9pzhj 2660 2 10 10 CD cord-005646-xhx9pzhj 2660 3 % % NN cord-005646-xhx9pzhj 2660 4 of of IN cord-005646-xhx9pzhj 2660 5 d d JJ cord-005646-xhx9pzhj 2660 6 - - : cord-005646-xhx9pzhj 2660 7 dldv~ dldv~ NNP cord-005646-xhx9pzhj 2660 8 tmslod tmslod NNP cord-005646-xhx9pzhj 2660 9 in in IN cord-005646-xhx9pzhj 2660 10 our -PRON- PRP$ cord-005646-xhx9pzhj 2660 11 PICU PICU NNP cord-005646-xhx9pzhj 2660 12 for for IN cord-005646-xhx9pzhj 2660 13 these these DT cord-005646-xhx9pzhj 2660 14 year~ year~ NNP cord-005646-xhx9pzhj 2660 15 exp exp NNP cord-005646-xhx9pzhj 2660 16 ~ ~ NNP cord-005646-xhx9pzhj 2660 17 dvncod dvncod NNP cord-005646-xhx9pzhj 2660 18 ~vcr~ ~vcr~ NNP cord-005646-xhx9pzhj 2660 19 attack attack NN cord-005646-xhx9pzhj 2660 20 for for IN cord-005646-xhx9pzhj 2660 21 the the DT cord-005646-xhx9pzhj 2660 22 flint flint NNP cord-005646-xhx9pzhj 2660 23 time time NN cord-005646-xhx9pzhj 2661 1 iu iu UH cord-005646-xhx9pzhj 2661 2 ~Jzeir ~Jzeir NNP cord-005646-xhx9pzhj 2661 3 lifts lift VBZ cord-005646-xhx9pzhj 2661 4 . . . cord-005646-xhx9pzhj 2662 1 It -PRON- PRP cord-005646-xhx9pzhj 2662 2 has have VBZ cord-005646-xhx9pzhj 2662 3 been be VBN cord-005646-xhx9pzhj 2662 4 cu~ cu~ VBN cord-005646-xhx9pzhj 2662 5 1~%~ 1~%~ CD cord-005646-xhx9pzhj 2662 6 children child NNS cord-005646-xhx9pzhj 2662 7 in in IN cord-005646-xhx9pzhj 2662 8 mspir mspir NNP cord-005646-xhx9pzhj 2662 9 ~ ~ NFP cord-005646-xhx9pzhj 2662 10 ry ry NNP cord-005646-xhx9pzhj 2662 11 PICU PICU NNP cord-005646-xhx9pzhj 2662 12 of of IN cord-005646-xhx9pzhj 2662 13 our -PRON- PRP$ cord-005646-xhx9pzhj 2662 14 Hos Hos NNP cord-005646-xhx9pzhj 2662 15 ~ ~ NNP cord-005646-xhx9pzhj 2662 16 mt mt NNP cord-005646-xhx9pzhj 2662 17 . . . cord-005646-xhx9pzhj 2663 1 The the DT cord-005646-xhx9pzhj 2663 2 scut~ scut~ NNP cord-005646-xhx9pzhj 2663 3 revere revere JJ cord-005646-xhx9pzhj 2663 4 attack attack NN cord-005646-xhx9pzhj 2663 5 ( ( -LRB- cord-005646-xhx9pzhj 2663 6 more more RBR cord-005646-xhx9pzhj 2663 7 ~asn ~asn NNP cord-005646-xhx9pzhj 2663 8 ~/o ~/o NFP cord-005646-xhx9pzhj 2663 9 of of IN cord-005646-xhx9pzhj 2663 10 hight hight JJ cord-005646-xhx9pzhj 2663 11 clinical clinical JJ cord-005646-xhx9pzhj 2663 12 score score NN cord-005646-xhx9pzhj 2663 13 ) ) -RRB- cord-005646-xhx9pzhj 2663 14 was be VBD cord-005646-xhx9pzhj 2663 15 detected detect VBN cord-005646-xhx9pzhj 2663 16 in in IN cord-005646-xhx9pzhj 2663 17 62 62 CD cord-005646-xhx9pzhj 2663 18 % % NN cord-005646-xhx9pzhj 2663 19 of of IN cord-005646-xhx9pzhj 2663 20 all all DT cord-005646-xhx9pzhj 2663 21 children child NNS cord-005646-xhx9pzhj 2663 22 admitted admit VBN cord-005646-xhx9pzhj 2663 23 with with IN cord-005646-xhx9pzhj 2663 24 respirak~ respirak~ NNP cord-005646-xhx9pzhj 2663 25 problems problem NNS cord-005646-xhx9pzhj 2663 26 . . . cord-005646-xhx9pzhj 2664 1 From from IN cord-005646-xhx9pzhj 2664 2 tl~ tl~ NNP cord-005646-xhx9pzhj 2664 3 mmlysss mmlysss NNP cord-005646-xhx9pzhj 2664 4 we -PRON- PRP cord-005646-xhx9pzhj 2664 5 exclu&d exclu&d CD cord-005646-xhx9pzhj 2664 6 : : : cord-005646-xhx9pzhj 2665 1 bmncldolifis bmncldolifis NNP cord-005646-xhx9pzhj 2665 2 , , , cord-005646-xhx9pzhj 2665 3 ~I ~I JJS cord-005646-xhx9pzhj 2665 4 anomalies anomaly NNS cord-005646-xhx9pzhj 2665 5 , , , cord-005646-xhx9pzhj 2665 6 ~eve~ ~eve~ NNP cord-005646-xhx9pzhj 2665 7 i i PRP cord-005646-xhx9pzhj 2665 8 ~ ~ CD cord-005646-xhx9pzhj 2665 9 ccqions ccqion NNS cord-005646-xhx9pzhj 2665 10 . . . cord-005646-xhx9pzhj 2666 1 Concerning concern VBG cord-005646-xhx9pzhj 2666 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2666 3 drug drug NN cord-005646-xhx9pzhj 2666 4 supplies supply NNS cord-005646-xhx9pzhj 2666 5 ( ( -LRB- cord-005646-xhx9pzhj 2666 6 which which WDT cord-005646-xhx9pzhj 2666 7 wc wc NNP cord-005646-xhx9pzhj 2666 8 ~ ~ NNP cord-005646-xhx9pzhj 2666 9 e e NN cord-005646-xhx9pzhj 2666 10 reduced reduce VBN cord-005646-xhx9pzhj 2666 11 ) ) -RRB- cord-005646-xhx9pzhj 2666 12 , , , cord-005646-xhx9pzhj 2666 13 we -PRON- PRP cord-005646-xhx9pzhj 2666 14 started start VBD cord-005646-xhx9pzhj 2666 15 our -PRON- PRP$ cord-005646-xhx9pzhj 2666 16 therapy therapy NN cord-005646-xhx9pzhj 2666 17 by by IN cord-005646-xhx9pzhj 2666 18 administration administration NN cord-005646-xhx9pzhj 2666 19 of of IN cord-005646-xhx9pzhj 2666 20 oxygen oxygen NN cord-005646-xhx9pzhj 2666 21 , , , cord-005646-xhx9pzhj 2666 22 ~ta2-ago ~ta2-ago NNP cord-005646-xhx9pzhj 2666 23 ~ ~ NFP cord-005646-xhx9pzhj 2666 24 dst dst IN cord-005646-xhx9pzhj 2666 25 inhalations inhalation NNS cord-005646-xhx9pzhj 2666 26 ( ( -LRB- cord-005646-xhx9pzhj 2667 1 but but CC cord-005646-xhx9pzhj 2667 2 sometimes sometimes RB cord-005646-xhx9pzhj 2667 3 we -PRON- PRP cord-005646-xhx9pzhj 2667 4 had have VBD cord-005646-xhx9pzhj 2667 5 the the DT cord-005646-xhx9pzhj 2667 6 solution solution NN cord-005646-xhx9pzhj 2667 7 for for IN cord-005646-xhx9pzhj 2667 8 jet jet NN cord-005646-xhx9pzhj 2667 9 nebulizcm nebulizcm NN cord-005646-xhx9pzhj 2667 10 only only RB cord-005646-xhx9pzhj 2667 11 for for IN cord-005646-xhx9pzhj 2667 12 o o NN cord-005646-xhx9pzhj 2667 13 ~ ~ NFP cord-005646-xhx9pzhj 2667 14 e e NN cord-005646-xhx9pzhj 2667 15 inhalation inhalation NN cord-005646-xhx9pzhj 2667 16 per per IN cord-005646-xhx9pzhj 2667 17 p p NN cord-005646-xhx9pzhj 2667 18 ~ ~ CD cord-005646-xhx9pzhj 2667 19 cnt cnt NNP cord-005646-xhx9pzhj 2667 20 ) ) -RRB- cord-005646-xhx9pzhj 2667 21 , , , cord-005646-xhx9pzhj 2667 22 mwinophyllin mwinophyllin NNP cord-005646-xhx9pzhj 2667 23 and and CC cord-005646-xhx9pzhj 2667 24 mefl mefl NNP cord-005646-xhx9pzhj 2668 1 ~ylpr ~ylpr NNP cord-005646-xhx9pzhj 2668 2 ~ ~ NFP cord-005646-xhx9pzhj 2668 3 Ini ini NN cord-005646-xhx9pzhj 2668 4 ~ ~ NFP cord-005646-xhx9pzhj 2668 5 done do VBN cord-005646-xhx9pzhj 2668 6 in in IN cord-005646-xhx9pzhj 2668 7 / / SYM cord-005646-xhx9pzhj 2668 8 ravenously ravenously RB cord-005646-xhx9pzhj 2668 9 . . . cord-005646-xhx9pzhj 2669 1 48 48 CD cord-005646-xhx9pzhj 2669 2 % % NN cord-005646-xhx9pzhj 2669 3 of of IN cord-005646-xhx9pzhj 2669 4 ih~ ih~ NN cord-005646-xhx9pzhj 2669 5 asthmatics asthmatic NNS cord-005646-xhx9pzhj 2669 6 needed need VBD cord-005646-xhx9pzhj 2669 7 repea~ repea~ NNP cord-005646-xhx9pzhj 2669 8 doses dose NNS cord-005646-xhx9pzhj 2669 9 of of IN cord-005646-xhx9pzhj 2669 10 muinophyl muinophyl NNP cord-005646-xhx9pzhj 2669 11 ~ ~ NFP cord-005646-xhx9pzhj 2669 12 n n CC cord-005646-xhx9pzhj 2669 13 pinch.ally pinch.ally NNP cord-005646-xhx9pzhj 2669 14 , , , cord-005646-xhx9pzhj 2669 15 tnch tnch NNP cord-005646-xhx9pzhj 2669 16 . . . cord-005646-xhx9pzhj 2670 1 , , , cord-005646-xhx9pzhj 2670 2 ding ding VB cord-005646-xhx9pzhj 2670 3 the the DT cord-005646-xhx9pzhj 2670 4 fluids fluid NNS cord-005646-xhx9pzhj 2670 5 . . . cord-005646-xhx9pzhj 2671 1 The the DT cord-005646-xhx9pzhj 2671 2 bronchodilak)r bronchodilak)r CD cord-005646-xhx9pzhj 2671 3 msponm msponm NNP cord-005646-xhx9pzhj 2671 4 was be VBD cord-005646-xhx9pzhj 2671 5 poor poor JJ cord-005646-xhx9pzhj 2672 1 ~r ~r XX cord-005646-xhx9pzhj 2673 1 ~cl ~cl NNP cord-005646-xhx9pzhj 2673 2 slow slow JJ cord-005646-xhx9pzhj 2673 3 , , , cord-005646-xhx9pzhj 2673 4 hospital hospital NN cord-005646-xhx9pzhj 2673 5 stay stay NN cord-005646-xhx9pzhj 2673 6 in in IN cord-005646-xhx9pzhj 2673 7 PICU PICU NNP cord-005646-xhx9pzhj 2673 8 was be VBD cord-005646-xhx9pzhj 2673 9 for for IN cord-005646-xhx9pzhj 2673 10 4 4 CD cord-005646-xhx9pzhj 2673 11 days day NNS cord-005646-xhx9pzhj 2673 12 and and CC cord-005646-xhx9pzhj 2673 13 for for IN cord-005646-xhx9pzhj 2673 14 14 14 CD cord-005646-xhx9pzhj 2673 15 days day NNS cord-005646-xhx9pzhj 2673 16 in in IN cord-005646-xhx9pzhj 2673 17 other other JJ cord-005646-xhx9pzhj 2673 18 units unit NNS cord-005646-xhx9pzhj 2673 19 sl sl NNP cord-005646-xhx9pzhj 2673 20 ~ ~ CD cord-005646-xhx9pzhj 2673 21 rwsvds rwsvds NNP cord-005646-xhx9pzhj 2673 22 . . . cord-005646-xhx9pzhj 2674 1 Tim Tim NNP cord-005646-xhx9pzhj 2674 2 ~ ~ NFP cord-005646-xhx9pzhj 2674 3 of of IN cord-005646-xhx9pzhj 2674 4 their -PRON- PRP$ cord-005646-xhx9pzhj 2674 5 stable stable JJ cord-005646-xhx9pzhj 2674 6 condifio~ condifio~ NNS cord-005646-xhx9pzhj 2674 7 was be VBD cord-005646-xhx9pzhj 2674 8 hard hard JJ cord-005646-xhx9pzhj 2674 9 at at IN cord-005646-xhx9pzhj 2674 10 borne bear VBN cord-005646-xhx9pzhj 2674 11 ( ( -LRB- cord-005646-xhx9pzhj 2674 12 or or CC cord-005646-xhx9pzhj 2674 13 refugees refugee NNS cord-005646-xhx9pzhj 2674 14 camps camp NNS cord-005646-xhx9pzhj 2674 15 ) ) -RRB- cord-005646-xhx9pzhj 2674 16 , , , cord-005646-xhx9pzhj 2674 17 without without IN cord-005646-xhx9pzhj 2674 18 p~ p~ XX cord-005646-xhx9pzhj 2675 1 ventkm ventkm NNP cord-005646-xhx9pzhj 2675 2 , , , cord-005646-xhx9pzhj 2675 3 so so RB cord-005646-xhx9pzhj 2675 4 they -PRON- PRP cord-005646-xhx9pzhj 2675 5 came come VBD cord-005646-xhx9pzhj 2675 6 bsvk bsvk NNP cord-005646-xhx9pzhj 2675 7 to to IN cord-005646-xhx9pzhj 2675 8 hospital hospital NN cord-005646-xhx9pzhj 2675 9 for for IN cord-005646-xhx9pzhj 2675 10 morn morn NN cord-005646-xhx9pzhj 2675 11 than than IN cord-005646-xhx9pzhj 2675 12 3 3 CD cord-005646-xhx9pzhj 2675 13 times time NNS cord-005646-xhx9pzhj 2675 14 in in IN cord-005646-xhx9pzhj 2675 15 27 27 CD cord-005646-xhx9pzhj 2675 16 % % NN cord-005646-xhx9pzhj 2675 17 of of IN cord-005646-xhx9pzhj 2675 18 cases case NNS cord-005646-xhx9pzhj 2675 19 , , , cord-005646-xhx9pzhj 2675 20 Dtrdng Dtrdng NNP cord-005646-xhx9pzhj 2675 21 ~e4Je ~e4je CD cord-005646-xhx9pzhj 2675 22 last last JJ cord-005646-xhx9pzhj 2675 23 motlfl motlfl NN cord-005646-xhx9pzhj 2675 24 ~ ~ NFP cord-005646-xhx9pzhj 2675 25 s s POS cord-005646-xhx9pzhj 2675 26 file file NN cord-005646-xhx9pzhj 2675 27 dtustion dtustion NN cord-005646-xhx9pzhj 2675 28 improved improve VBD cord-005646-xhx9pzhj 2675 29 , , , cord-005646-xhx9pzhj 2675 30 concerning concern VBG cord-005646-xhx9pzhj 2675 31 tim tim NNP cord-005646-xhx9pzhj 2675 32 drugs drug NNS cord-005646-xhx9pzhj 2675 33 supply supply VBP cord-005646-xhx9pzhj 2675 34 for for IN cord-005646-xhx9pzhj 2675 35 prevention prevention NN cord-005646-xhx9pzhj 2675 36 , , , cord-005646-xhx9pzhj 2675 37 and and CC cord-005646-xhx9pzhj 2675 38 we -PRON- PRP cord-005646-xhx9pzhj 2675 39 hope hope VBP cord-005646-xhx9pzhj 2675 40 that that IN cord-005646-xhx9pzhj 2675 41 these these DT cord-005646-xhx9pzhj 2675 42 lifc lifc NNP cord-005646-xhx9pzhj 2675 43 ~ ~ CD cord-005646-xhx9pzhj 2675 44 restening restening NN cord-005646-xhx9pzhj 2675 45 conditions condition NNS cord-005646-xhx9pzhj 2676 1 wouldd~ wouldd~ NNP cord-005646-xhx9pzhj 2677 1 Introduction introduction NN cord-005646-xhx9pzhj 2677 2 : : : cord-005646-xhx9pzhj 2677 3 The the DT cord-005646-xhx9pzhj 2677 4 incidence incidence NN cord-005646-xhx9pzhj 2677 5 of of IN cord-005646-xhx9pzhj 2677 6 ARDS ARDS NNP cord-005646-xhx9pzhj 2677 7 is be VBZ cord-005646-xhx9pzhj 2677 8 increasing increase VBG cord-005646-xhx9pzhj 2677 9 as as IN cord-005646-xhx9pzhj 2677 10 survival survival NN cord-005646-xhx9pzhj 2677 11 of of IN cord-005646-xhx9pzhj 2677 12 critically critically RB cord-005646-xhx9pzhj 2677 13 ill ill JJ cord-005646-xhx9pzhj 2677 14 patients patient NNS cord-005646-xhx9pzhj 2677 15 is be VBZ cord-005646-xhx9pzhj 2677 16 higher high JJR cord-005646-xhx9pzhj 2677 17 . . . cord-005646-xhx9pzhj 2678 1 The the DT cord-005646-xhx9pzhj 2678 2 application application NN cord-005646-xhx9pzhj 2678 3 of of IN cord-005646-xhx9pzhj 2678 4 new new JJ cord-005646-xhx9pzhj 2678 5 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2678 6 modalities modality NNS cord-005646-xhx9pzhj 2678 7 have have VBP cord-005646-xhx9pzhj 2678 8 increased increase VBN cord-005646-xhx9pzhj 2678 9 the the DT cord-005646-xhx9pzhj 2678 10 survival survival NN cord-005646-xhx9pzhj 2678 11 rates rate NNS cord-005646-xhx9pzhj 2678 12 in in IN cord-005646-xhx9pzhj 2678 13 ( ( -LRB- cord-005646-xhx9pzhj 2678 14 ARDS ARDS NNP cord-005646-xhx9pzhj 2678 15 ) ) -RRB- cord-005646-xhx9pzhj 2678 16 adult adult NN cord-005646-xhx9pzhj 2678 17 patients patient NNS cord-005646-xhx9pzhj 2678 18 . . . cord-005646-xhx9pzhj 2679 1 Objective objective NN cord-005646-xhx9pzhj 2679 2 : : : cord-005646-xhx9pzhj 2680 1 To to TO cord-005646-xhx9pzhj 2680 2 study study VB cord-005646-xhx9pzhj 2680 3 the the DT cord-005646-xhx9pzhj 2680 4 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2680 5 efficacy efficacy NN cord-005646-xhx9pzhj 2680 6 of of IN cord-005646-xhx9pzhj 2680 7 new new JJ cord-005646-xhx9pzhj 2680 8 tleamlents tleamlent NNS cord-005646-xhx9pzhj 2680 9 in in IN cord-005646-xhx9pzhj 2680 10 children child NNS cord-005646-xhx9pzhj 2680 11 with with IN cord-005646-xhx9pzhj 2680 12 ARDS ARDS NNP cord-005646-xhx9pzhj 2680 13 Material Material NNP cord-005646-xhx9pzhj 2680 14 and and CC cord-005646-xhx9pzhj 2680 15 methods method NNS cord-005646-xhx9pzhj 2680 16 : : : cord-005646-xhx9pzhj 2680 17 A a DT cord-005646-xhx9pzhj 2680 18 retros retro NNS cord-005646-xhx9pzhj 2680 19 ~ ~ NFP cord-005646-xhx9pzhj 2680 20 ctive ctive JJ cord-005646-xhx9pzhj 2680 21 study study NN cord-005646-xhx9pzhj 2680 22 was be VBD cord-005646-xhx9pzhj 2680 23 conducted conduct VBN cord-005646-xhx9pzhj 2680 24 from from IN cord-005646-xhx9pzhj 2680 25 1990 1990 CD cord-005646-xhx9pzhj 2680 26 to to IN cord-005646-xhx9pzhj 2680 27 1995 1995 CD cord-005646-xhx9pzhj 2680 28 . . . cord-005646-xhx9pzhj 2681 1 17 17 CD cord-005646-xhx9pzhj 2681 2 children child NNS cord-005646-xhx9pzhj 2681 3 with with IN cord-005646-xhx9pzhj 2681 4 severe severe JJ cord-005646-xhx9pzhj 2681 5 ARDS ARDS NNP cord-005646-xhx9pzhj 2681 6 , , , cord-005646-xhx9pzhj 2681 7 ( ( -LRB- cord-005646-xhx9pzhj 2681 8 lung lung NN cord-005646-xhx9pzhj 2681 9 severity severity NN cord-005646-xhx9pzhj 2681 10 score score NN cord-005646-xhx9pzhj 2681 11 > > XX cord-005646-xhx9pzhj 2682 1 2,5 2,5 LS cord-005646-xhx9pzhj 2682 2 ) ) -RRB- cord-005646-xhx9pzhj 2683 1 ( ( -LRB- cord-005646-xhx9pzhj 2683 2 R R NNP cord-005646-xhx9pzhj 2683 3 ) ) -RRB- cord-005646-xhx9pzhj 2683 4 , , , cord-005646-xhx9pzhj 2683 5 aged age VBN cord-005646-xhx9pzhj 2683 6 15 15 CD cord-005646-xhx9pzhj 2683 7 days day NNS cord-005646-xhx9pzhj 2683 8 to to IN cord-005646-xhx9pzhj 2683 9 16 16 CD cord-005646-xhx9pzhj 2683 10 years year NNS cord-005646-xhx9pzhj 2683 11 , , , cord-005646-xhx9pzhj 2683 12 were be VBD cord-005646-xhx9pzhj 2683 13 included include VBN cord-005646-xhx9pzhj 2683 14 . . . cord-005646-xhx9pzhj 2684 1 The the DT cord-005646-xhx9pzhj 2684 2 diagnosis diagnosis NN cord-005646-xhx9pzhj 2684 3 were be VBD cord-005646-xhx9pzhj 2684 4 as as IN cord-005646-xhx9pzhj 2684 5 follows follow VBZ cord-005646-xhx9pzhj 2684 6 : : : cord-005646-xhx9pzhj 2684 7 9 9 CD cord-005646-xhx9pzhj 2684 8 interstitial interstitial JJ cord-005646-xhx9pzhj 2684 9 pneumonitis pneumonitis NN cord-005646-xhx9pzhj 2684 10 , , , cord-005646-xhx9pzhj 2684 11 5 5 CD cord-005646-xhx9pzhj 2684 12 non non JJ cord-005646-xhx9pzhj 2684 13 interstitial interstitial JJ cord-005646-xhx9pzhj 2684 14 lung lung NN cord-005646-xhx9pzhj 2684 15 infection infection NN cord-005646-xhx9pzhj 2684 16 , , , cord-005646-xhx9pzhj 2684 17 2 2 CD cord-005646-xhx9pzhj 2684 18 with with IN cord-005646-xhx9pzhj 2684 19 lung lung NN cord-005646-xhx9pzhj 2684 20 aspiration aspiration NN cord-005646-xhx9pzhj 2684 21 and and CC cord-005646-xhx9pzhj 2684 22 1 1 CD cord-005646-xhx9pzhj 2684 23 with with IN cord-005646-xhx9pzhj 2684 24 clinical clinical JJ cord-005646-xhx9pzhj 2684 25 sepsis sepsis NN cord-005646-xhx9pzhj 2684 26 . . . cord-005646-xhx9pzhj 2685 1 5 5 CD cord-005646-xhx9pzhj 2685 2 patients patient NNS cord-005646-xhx9pzhj 2685 3 had have VBD cord-005646-xhx9pzhj 2685 4 different different JJ cord-005646-xhx9pzhj 2685 5 tipes tipe NNS cord-005646-xhx9pzhj 2685 6 of of IN cord-005646-xhx9pzhj 2685 7 cancer cancer NN cord-005646-xhx9pzhj 2685 8 and and CC cord-005646-xhx9pzhj 2685 9 4 4 CD cord-005646-xhx9pzhj 2685 10 to to TO cord-005646-xhx9pzhj 2685 11 suffer suffer VB cord-005646-xhx9pzhj 2685 12 inmunodeficiency inmunodeficiency NN cord-005646-xhx9pzhj 2685 13 disease disease NN cord-005646-xhx9pzhj 2685 14 , , , cord-005646-xhx9pzhj 2685 15 The the DT cord-005646-xhx9pzhj 2685 16 first first JJ cord-005646-xhx9pzhj 2685 17 8 8 CD cord-005646-xhx9pzhj 2685 18 subjects subject NNS cord-005646-xhx9pzhj 2685 19 ( ( -LRB- cord-005646-xhx9pzhj 2685 20 Group Group NNP cord-005646-xhx9pzhj 2685 21 t t NN cord-005646-xhx9pzhj 2685 22 ) ) -RRB- cord-005646-xhx9pzhj 2685 23 were be VBD cord-005646-xhx9pzhj 2685 24 treated treat VBN cord-005646-xhx9pzhj 2685 25 with with IN cord-005646-xhx9pzhj 2685 26 conventional conventional JJ cord-005646-xhx9pzhj 2685 27 measures measure NNS cord-005646-xhx9pzhj 2685 28 . . . cord-005646-xhx9pzhj 2686 1 From from IN cord-005646-xhx9pzhj 2686 2 October October NNP cord-005646-xhx9pzhj 2686 3 of of IN cord-005646-xhx9pzhj 2686 4 1994new 1994new CD cord-005646-xhx9pzhj 2686 5 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2686 6 modalities modality NNS cord-005646-xhx9pzhj 2686 7 were be VBD cord-005646-xhx9pzhj 2686 8 introduced introduce VBN cord-005646-xhx9pzhj 2686 9 , , , cord-005646-xhx9pzhj 2686 10 including include VBG cord-005646-xhx9pzhj 2686 11 : : : cord-005646-xhx9pzhj 2686 12 less less RBR cord-005646-xhx9pzhj 2686 13 agressive agressive JJ cord-005646-xhx9pzhj 2686 14 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2686 15 support support NN cord-005646-xhx9pzhj 2686 16 , , , cord-005646-xhx9pzhj 2686 17 postural postural JJ cord-005646-xhx9pzhj 2686 18 changes change NNS cord-005646-xhx9pzhj 2686 19 ( ( -LRB- cord-005646-xhx9pzhj 2686 20 prone prone JJ cord-005646-xhx9pzhj 2686 21 to to IN cord-005646-xhx9pzhj 2686 22 supine supine JJ cord-005646-xhx9pzhj 2686 23 ) ) -RRB- cord-005646-xhx9pzhj 2686 24 in in IN cord-005646-xhx9pzhj 2686 25 9 9 CD cord-005646-xhx9pzhj 2686 26 subjects subject NNS cord-005646-xhx9pzhj 2686 27 , , , cord-005646-xhx9pzhj 2686 28 administration administration NN cord-005646-xhx9pzhj 2686 29 of of IN cord-005646-xhx9pzhj 2686 30 corticosteroids corticosteroid NNS cord-005646-xhx9pzhj 2686 31 in in IN cord-005646-xhx9pzhj 2686 32 8 8 CD cord-005646-xhx9pzhj 2686 33 patients patient NNS cord-005646-xhx9pzhj 2686 34 , , , cord-005646-xhx9pzhj 2686 35 rfitric rfitric NN cord-005646-xhx9pzhj 2686 36 oxide oxide NN cord-005646-xhx9pzhj 2686 37 in in IN cord-005646-xhx9pzhj 2686 38 3 3 CD cord-005646-xhx9pzhj 2686 39 , , , cord-005646-xhx9pzhj 2686 40 pe pe NNP cord-005646-xhx9pzhj 2686 41 ~ ~ NFP cord-005646-xhx9pzhj 2686 42 ssive ssive NNP cord-005646-xhx9pzhj 2686 43 hypercapnia hypercapnia NNP cord-005646-xhx9pzhj 2686 44 and and CC cord-005646-xhx9pzhj 2686 45 administration administration NNP cord-005646-xhx9pzhj 2686 46 of of IN cord-005646-xhx9pzhj 2686 47 exogeans exogeans NNP cord-005646-xhx9pzhj 2686 48 sarfactant sarfactant NNP cord-005646-xhx9pzhj 2686 49 in in IN cord-005646-xhx9pzhj 2686 50 one one CD cord-005646-xhx9pzhj 2686 51 , , , cord-005646-xhx9pzhj 2686 52 PaO2 PaO2 NNS cord-005646-xhx9pzhj 2686 53 / / SYM cord-005646-xhx9pzhj 2686 54 FiO2 FiO2 NNS cord-005646-xhx9pzhj 2686 55 , , , cord-005646-xhx9pzhj 2686 56 D(A D(A NNP cord-005646-xhx9pzhj 2686 57 - - HYPH cord-005646-xhx9pzhj 2686 58 a)O2 a)O2 NNS cord-005646-xhx9pzhj 2686 59 , , , cord-005646-xhx9pzhj 2686 60 oxigenation oxigenation NN cord-005646-xhx9pzhj 2686 61 index index NN cord-005646-xhx9pzhj 2686 62 ( ( -LRB- cord-005646-xhx9pzhj 2686 63 OI OI NNP cord-005646-xhx9pzhj 2686 64 ) ) -RRB- cord-005646-xhx9pzhj 2686 65 and and CC cord-005646-xhx9pzhj 2686 66 the the DT cord-005646-xhx9pzhj 2686 67 score score NN cord-005646-xhx9pzhj 2686 68 of of IN cord-005646-xhx9pzhj 2686 69 respirator respirator NN cord-005646-xhx9pzhj 2686 70 ) ) -RRB- cord-005646-xhx9pzhj 2686 71 , , , cord-005646-xhx9pzhj 2686 72 severity severity NN cord-005646-xhx9pzhj 2686 73 disease disease NN cord-005646-xhx9pzhj 2686 74 were be VBD cord-005646-xhx9pzhj 2686 75 similar similar JJ cord-005646-xhx9pzhj 2686 76 in in IN cord-005646-xhx9pzhj 2686 77 both both DT cord-005646-xhx9pzhj 2686 78 groups group NNS cord-005646-xhx9pzhj 2686 79 . . . cord-005646-xhx9pzhj 2687 1 The the DT cord-005646-xhx9pzhj 2687 2 two two CD cord-005646-xhx9pzhj 2687 3 groups group NNS cord-005646-xhx9pzhj 2687 4 evolntiou evolntiou NNP cord-005646-xhx9pzhj 2687 5 was be VBD cord-005646-xhx9pzhj 2687 6 compared compare VBN cord-005646-xhx9pzhj 2687 7 . . . cord-005646-xhx9pzhj 2688 1 Results result NNS cord-005646-xhx9pzhj 2688 2 : : : cord-005646-xhx9pzhj 2689 1 -Ten -ten PRP$ cord-005646-xhx9pzhj 2689 2 patients patient NNS cord-005646-xhx9pzhj 2689 3 died die VBD cord-005646-xhx9pzhj 2689 4 , , , cord-005646-xhx9pzhj 2689 5 6 6 CD cord-005646-xhx9pzhj 2689 6 from from IN cord-005646-xhx9pzhj 2689 7 group group NN cord-005646-xhx9pzhj 2689 8 I I NNP cord-005646-xhx9pzhj 2689 9 and and CC cord-005646-xhx9pzhj 2689 10 4 4 CD cord-005646-xhx9pzhj 2689 11 from from IN cord-005646-xhx9pzhj 2689 12 group group NN cord-005646-xhx9pzhj 2689 13 II II NNP cord-005646-xhx9pzhj 2689 14 ( ( -LRB- cord-005646-xhx9pzhj 2689 15 75 75 CD cord-005646-xhx9pzhj 2689 16 % % NN cord-005646-xhx9pzhj 2689 17 v.s.44:4%,NS v.s.44:4%,NS NNP cord-005646-xhx9pzhj 2689 18 ) ) -RRB- cord-005646-xhx9pzhj 2689 19 . . . cord-005646-xhx9pzhj 2690 1 -The -The : cord-005646-xhx9pzhj 2690 2 evolution evolution NN cord-005646-xhx9pzhj 2690 3 time time NN cord-005646-xhx9pzhj 2690 4 , , , cord-005646-xhx9pzhj 2690 5 either either CC cord-005646-xhx9pzhj 2690 6 to to TO cord-005646-xhx9pzhj 2690 7 exitus exitus VB cord-005646-xhx9pzhj 2690 8 or or CC cord-005646-xhx9pzhj 2690 9 weaning wean VBG cord-005646-xhx9pzhj 2690 10 from from IN cord-005646-xhx9pzhj 2690 11 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2690 12 support support NN cord-005646-xhx9pzhj 2690 13 was be VBD cord-005646-xhx9pzhj 2690 14 higher high JJR cord-005646-xhx9pzhj 2690 15 in in IN cord-005646-xhx9pzhj 2690 16 group group NN cord-005646-xhx9pzhj 2690 17 II II NNP cord-005646-xhx9pzhj 2690 18 ( ( -LRB- cord-005646-xhx9pzhj 2690 19 22.9 22.9 CD cord-005646-xhx9pzhj 2690 20 v.s. v.s. NNP cord-005646-xhx9pzhj 2690 21 13.6days 13.6days CD cord-005646-xhx9pzhj 2690 22 in in IN cord-005646-xhx9pzhj 2690 23 group group NN cord-005646-xhx9pzhj 2691 1 I -PRON- PRP cord-005646-xhx9pzhj 2691 2 , , , cord-005646-xhx9pzhj 2691 3 NS NS NNP cord-005646-xhx9pzhj 2691 4 ) ) -RRB- cord-005646-xhx9pzhj 2691 5 , , , cord-005646-xhx9pzhj 2691 6 -The -the WDT cord-005646-xhx9pzhj 2691 7 incidence incidence NN cord-005646-xhx9pzhj 2691 8 of of IN cord-005646-xhx9pzhj 2691 9 barotrauma barotrauma NN cord-005646-xhx9pzhj 2691 10 was be VBD cord-005646-xhx9pzhj 2691 11 observed observe VBN cord-005646-xhx9pzhj 2691 12 in in IN cord-005646-xhx9pzhj 2691 13 12 12 CD cord-005646-xhx9pzhj 2691 14 subjects subject NNS cord-005646-xhx9pzhj 2691 15 ( ( -LRB- cord-005646-xhx9pzhj 2691 16 70.6 70.6 CD cord-005646-xhx9pzhj 2691 17 % % NN cord-005646-xhx9pzhj 2691 18 ) ) -RRB- cord-005646-xhx9pzhj 2691 19 , , , cord-005646-xhx9pzhj 2691 20 6 6 CD cord-005646-xhx9pzhj 2691 21 from from IN cord-005646-xhx9pzhj 2691 22 group group NN cord-005646-xhx9pzhj 2691 23 I I NNP cord-005646-xhx9pzhj 2691 24 and and CC cord-005646-xhx9pzhj 2691 25 6 6 CD cord-005646-xhx9pzhj 2691 26 from from IN cord-005646-xhx9pzhj 2691 27 II II NNP cord-005646-xhx9pzhj 2691 28 . . . cord-005646-xhx9pzhj 2692 1 Of of IN cord-005646-xhx9pzhj 2692 2 these these DT cord-005646-xhx9pzhj 2692 3 patients patient NNS cord-005646-xhx9pzhj 2692 4 75 75 CD cord-005646-xhx9pzhj 2692 5 % % NN cord-005646-xhx9pzhj 2692 6 expired expire VBD cord-005646-xhx9pzhj 2692 7 . . . cord-005646-xhx9pzhj 2693 1 -During -dure VBG cord-005646-xhx9pzhj 2693 2 the the DT cord-005646-xhx9pzhj 2693 3 course course NN cord-005646-xhx9pzhj 2693 4 of of IN cord-005646-xhx9pzhj 2693 5 the the DT cord-005646-xhx9pzhj 2693 6 disease disease NN cord-005646-xhx9pzhj 2693 7 , , , cord-005646-xhx9pzhj 2693 8 15 15 CD cord-005646-xhx9pzhj 2693 9 ( ( -LRB- cord-005646-xhx9pzhj 2693 10 88 88 CD cord-005646-xhx9pzhj 2693 11 % % NN cord-005646-xhx9pzhj 2693 12 ) ) -RRB- cord-005646-xhx9pzhj 2693 13 patients patient NNS cord-005646-xhx9pzhj 2693 14 had have VBD cord-005646-xhx9pzhj 2693 15 more more JJR cord-005646-xhx9pzhj 2693 16 than than IN cord-005646-xhx9pzhj 2693 17 one one CD cord-005646-xhx9pzhj 2693 18 damaged damage VBN cord-005646-xhx9pzhj 2693 19 organ organ NN cord-005646-xhx9pzhj 2693 20 . . . cord-005646-xhx9pzhj 2694 1 Only only RB cord-005646-xhx9pzhj 2694 2 in in IN cord-005646-xhx9pzhj 2694 3 one one CD cord-005646-xhx9pzhj 2694 4 subjet subjet NN cord-005646-xhx9pzhj 2694 5 MOF MOF NNP cord-005646-xhx9pzhj 2694 6 was be VBD cord-005646-xhx9pzhj 2694 7 considered consider VBN cord-005646-xhx9pzhj 2694 8 to to TO cord-005646-xhx9pzhj 2694 9 be be VB cord-005646-xhx9pzhj 2694 10 the the DT cord-005646-xhx9pzhj 2694 11 main main JJ cord-005646-xhx9pzhj 2694 12 cause cause NN cord-005646-xhx9pzhj 2694 13 of of IN cord-005646-xhx9pzhj 2694 14 death death NN cord-005646-xhx9pzhj 2694 15 . . . cord-005646-xhx9pzhj 2695 1 The the DT cord-005646-xhx9pzhj 2695 2 majority majority NN cord-005646-xhx9pzhj 2695 3 of of IN cord-005646-xhx9pzhj 2695 4 the the DT cord-005646-xhx9pzhj 2695 5 patients patient NNS cord-005646-xhx9pzhj 2695 6 expired expire VBD cord-005646-xhx9pzhj 2695 7 because because IN cord-005646-xhx9pzhj 2695 8 of of IN cord-005646-xhx9pzhj 2695 9 their -PRON- PRP$ cord-005646-xhx9pzhj 2695 10 respiratory respiratory JJ cord-005646-xhx9pzhj 2695 11 disease disease NN cord-005646-xhx9pzhj 2695 12 , , , cord-005646-xhx9pzhj 2695 13 although although RB cord-005646-xhx9pzhj 2695 14 , , , cord-005646-xhx9pzhj 2695 15 80 80 CD cord-005646-xhx9pzhj 2695 16 % % NN cord-005646-xhx9pzhj 2695 17 of of IN cord-005646-xhx9pzhj 2695 18 them -PRON- PRP cord-005646-xhx9pzhj 2695 19 met meet VBD cord-005646-xhx9pzhj 2695 20 criteria criterion NNS cord-005646-xhx9pzhj 2695 21 of of IN cord-005646-xhx9pzhj 2695 22 MOF MOF NNP cord-005646-xhx9pzhj 2695 23 . . . cord-005646-xhx9pzhj 2696 1 -Fifty -Fifty NNP cord-005646-xhx9pzhj 2696 2 percent percent NN cord-005646-xhx9pzhj 2696 3 of of IN cord-005646-xhx9pzhj 2696 4 the the DT cord-005646-xhx9pzhj 2696 5 subjects subject NNS cord-005646-xhx9pzhj 2696 6 were be VBD cord-005646-xhx9pzhj 2696 7 infected infect VBN cord-005646-xhx9pzhj 2696 8 at at IN cord-005646-xhx9pzhj 2696 9 the the DT cord-005646-xhx9pzhj 2696 10 time time NN cord-005646-xhx9pzhj 2696 11 of of IN cord-005646-xhx9pzhj 2696 12 death death NN cord-005646-xhx9pzhj 2696 13 . . . cord-005646-xhx9pzhj 2697 1 Stmmry Stmmry NNS cord-005646-xhx9pzhj 2697 2 : : : cord-005646-xhx9pzhj 2698 1 a a DT cord-005646-xhx9pzhj 2698 2 trend trend NN cord-005646-xhx9pzhj 2698 3 toward toward IN cord-005646-xhx9pzhj 2698 4 a a DT cord-005646-xhx9pzhj 2698 5 higher high JJR cord-005646-xhx9pzhj 2698 6 survival survival NN cord-005646-xhx9pzhj 2698 7 rate rate NN cord-005646-xhx9pzhj 2698 8 is be VBZ cord-005646-xhx9pzhj 2698 9 observed observe VBN cord-005646-xhx9pzhj 2698 10 in in IN cord-005646-xhx9pzhj 2698 11 the the DT cord-005646-xhx9pzhj 2698 12 subjects subject NNS cord-005646-xhx9pzhj 2698 13 receiving receive VBG cord-005646-xhx9pzhj 2698 14 the the DT cord-005646-xhx9pzhj 2698 15 new new JJ cord-005646-xhx9pzhj 2698 16 modalifies modalifie NNS cord-005646-xhx9pzhj 2698 17 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2698 18 intervention intervention NN cord-005646-xhx9pzhj 2698 19 ( ( -LRB- cord-005646-xhx9pzhj 2698 20 corticosteroides corticosteroide NNS cord-005646-xhx9pzhj 2698 21 , , , cord-005646-xhx9pzhj 2698 22 postural postural JJ cord-005646-xhx9pzhj 2698 23 changes change NNS cord-005646-xhx9pzhj 2698 24 and and CC cord-005646-xhx9pzhj 2698 25 permissive permissive JJ cord-005646-xhx9pzhj 2698 26 hypercapnia hypercapnia NN cord-005646-xhx9pzhj 2698 27 ) ) -RRB- cord-005646-xhx9pzhj 2698 28 . . . cord-005646-xhx9pzhj 2699 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 2699 2 results result NNS cord-005646-xhx9pzhj 2699 3 are be VBP cord-005646-xhx9pzhj 2699 4 not not RB cord-005646-xhx9pzhj 2699 5 significative significative JJ cord-005646-xhx9pzhj 2699 6 , , , cord-005646-xhx9pzhj 2699 7 probably probably RB cord-005646-xhx9pzhj 2699 8 because because IN cord-005646-xhx9pzhj 2699 9 of of IN cord-005646-xhx9pzhj 2699 10 the the DT cord-005646-xhx9pzhj 2699 11 small small JJ cord-005646-xhx9pzhj 2699 12 number number NN cord-005646-xhx9pzhj 2699 13 of of IN cord-005646-xhx9pzhj 2699 14 subjects subject NNS cord-005646-xhx9pzhj 2699 15 studied study VBN cord-005646-xhx9pzhj 2699 16 . . . cord-005646-xhx9pzhj 2700 1 A a DT cord-005646-xhx9pzhj 2700 2 new new JJ cord-005646-xhx9pzhj 2700 3 doubleAurae~ doubleaurae~ NN cord-005646-xhx9pzhj 2701 1 t t NNP cord-005646-xhx9pzhj 2701 2 two two CD cord-005646-xhx9pzhj 2701 3 - - HYPH cord-005646-xhx9pzhj 2701 4 stage stage NN cord-005646-xhx9pzhj 2701 5 ET et NN cord-005646-xhx9pzhj 2701 6 - - HYPH cord-005646-xhx9pzhj 2701 7 tube tube NN cord-005646-xhx9pzhj 2701 8 ( ( -LRB- cord-005646-xhx9pzhj 2701 9 DL dl NN cord-005646-xhx9pzhj 2701 10 - - HYPH cord-005646-xhx9pzhj 2701 11 ETT ETT NNP cord-005646-xhx9pzhj 2701 12 ) ) -RRB- cord-005646-xhx9pzhj 2701 13 was be VBD cord-005646-xhx9pzhj 2701 14 desig desig NNS cord-005646-xhx9pzhj 2701 15 ~ ~ NFP cord-005646-xhx9pzhj 2701 16 aed aed NNP cord-005646-xhx9pzhj 2701 17 and and CC cord-005646-xhx9pzhj 2701 18 tested test VBN cord-005646-xhx9pzhj 2701 19 in in IN cord-005646-xhx9pzhj 2701 20 the the DT cord-005646-xhx9pzhj 2701 21 rabbits rabbit NNS cord-005646-xhx9pzhj 2701 22 with with IN cord-005646-xhx9pzhj 2701 23 acute acute JJ cord-005646-xhx9pzhj 2701 24 king king NN cord-005646-xhx9pzhj 2701 25 injury injury NN cord-005646-xhx9pzhj 2701 26 under under IN cord-005646-xhx9pzhj 2701 27 conventional conventional JJ cord-005646-xhx9pzhj 2701 28 mechanical mechanical JJ cord-005646-xhx9pzhj 2701 29 ~entilation ~entilation NNP cord-005646-xhx9pzhj 2701 30 _ _ NN cord-005646-xhx9pzhj 2701 31 Ventilation ventilation NN cord-005646-xhx9pzhj 2701 32 efficiency efficiency NN cord-005646-xhx9pzhj 2701 33 of of IN cord-005646-xhx9pzhj 2701 34 DL dl NN cord-005646-xhx9pzhj 2701 35 - - HYPH cord-005646-xhx9pzhj 2701 36 ETT ETT NNP cord-005646-xhx9pzhj 2701 37 was be VBD cord-005646-xhx9pzhj 2701 38 emrrpared emrrpare VBN cord-005646-xhx9pzhj 2701 39 with with IN cord-005646-xhx9pzhj 2701 40 that that DT cord-005646-xhx9pzhj 2701 41 of of IN cord-005646-xhx9pzhj 2701 42 canveniionally canveniionally RB cord-005646-xhx9pzhj 2701 43 t t XX cord-005646-xhx9pzhj 2701 44 ~ ~ CD cord-005646-xhx9pzhj 2701 45 sed sed NNP cord-005646-xhx9pzhj 2701 46 single single JJ cord-005646-xhx9pzhj 2701 47 lumen lumen NN cord-005646-xhx9pzhj 2701 48 ET et NN cord-005646-xhx9pzhj 2701 49 - - HYPH cord-005646-xhx9pzhj 2701 50 tube tube NN cord-005646-xhx9pzhj 2701 51 ( ( -LRB- cord-005646-xhx9pzhj 2701 52 SL SL NNP cord-005646-xhx9pzhj 2701 53 - - HYPH cord-005646-xhx9pzhj 2701 54 ETT ETT NNP cord-005646-xhx9pzhj 2701 55 ) ) -RRB- cord-005646-xhx9pzhj 2701 56 . . . cord-005646-xhx9pzhj 2702 1 Meth Meth NNP cord-005646-xhx9pzhj 2702 2 ~ ~ NFP cord-005646-xhx9pzhj 2702 3 s s NN cord-005646-xhx9pzhj 2702 4 : : : cord-005646-xhx9pzhj 2703 1 DL DL NNP cord-005646-xhx9pzhj 2703 2 - - HYPH cord-005646-xhx9pzhj 2703 3 ETT ETT NNP cord-005646-xhx9pzhj 2703 4 was be VBD cord-005646-xhx9pzhj 2703 5 specially specially RB cord-005646-xhx9pzhj 2703 6 made make VBN cord-005646-xhx9pzhj 2703 7 out out IN cord-005646-xhx9pzhj 2703 8 of of IN cord-005646-xhx9pzhj 2703 9 two two CD cord-005646-xhx9pzhj 2703 10 SL SL NNP cord-005646-xhx9pzhj 2703 11 - - HYPH cord-005646-xhx9pzhj 2703 12 ETT ETT NNP cord-005646-xhx9pzhj 2703 13 . . . cord-005646-xhx9pzhj 2704 1 Vertical vertical JJ cord-005646-xhx9pzhj 2704 2 crosssections crosssection NNS cord-005646-xhx9pzhj 2704 3 at at IN cord-005646-xhx9pzhj 2704 4 the the DT cord-005646-xhx9pzhj 2704 5 distal distal JJ cord-005646-xhx9pzhj 2704 6 end end NN cord-005646-xhx9pzhj 2704 7 of of IN cord-005646-xhx9pzhj 2704 8 two two CD cord-005646-xhx9pzhj 2704 9 ET et NN cord-005646-xhx9pzhj 2704 10 - - HYPH cord-005646-xhx9pzhj 2704 11 tube tube NN cord-005646-xhx9pzhj 2704 12 ( ( -LRB- cord-005646-xhx9pzhj 2704 13 tD td NN cord-005646-xhx9pzhj 2704 14 3_0 3_0 CD cord-005646-xhx9pzhj 2704 15 rmn rmn NNP cord-005646-xhx9pzhj 2704 16 Portax Portax NNP cord-005646-xhx9pzhj 2704 17 ) ) -RRB- cord-005646-xhx9pzhj 2704 18 were be VBD cord-005646-xhx9pzhj 2704 19 adhered adhere VBN cord-005646-xhx9pzhj 2704 20 with with IN cord-005646-xhx9pzhj 2704 21 each each DT cord-005646-xhx9pzhj 2704 22 other other JJ cord-005646-xhx9pzhj 2704 23 to to TO cord-005646-xhx9pzhj 2704 24 form form VB cord-005646-xhx9pzhj 2704 25 a a DT cord-005646-xhx9pzhj 2704 26 tracheal tracheal JJ cord-005646-xhx9pzhj 2704 27 stage stage NN cord-005646-xhx9pzhj 2704 28 lumen lumen NN cord-005646-xhx9pzhj 2704 29 wifu wifu NN cord-005646-xhx9pzhj 2704 30 ID ID NNP cord-005646-xhx9pzhj 2704 31 3.0 3.0 CD cord-005646-xhx9pzhj 2704 32 mm mm NN cord-005646-xhx9pzhj 2705 1 The the DT cord-005646-xhx9pzhj 2705 2 two two CD cord-005646-xhx9pzhj 2705 3 remained remain VBD cord-005646-xhx9pzhj 2705 4 uncut uncut JJ cord-005646-xhx9pzhj 2705 5 parts part NNS cord-005646-xhx9pzhj 2705 6 of of IN cord-005646-xhx9pzhj 2705 7 the the DT cord-005646-xhx9pzhj 2705 8 tubes tube NNS cord-005646-xhx9pzhj 2705 9 corLntithted corlntithte VBD cord-005646-xhx9pzhj 2705 10 the the DT cord-005646-xhx9pzhj 2705 11 oval oval NN cord-005646-xhx9pzhj 2705 12 s s NNP cord-005646-xhx9pzhj 2705 13 ~ ~ NFP cord-005646-xhx9pzhj 2705 14 ge ge NNP cord-005646-xhx9pzhj 2705 15 with with IN cord-005646-xhx9pzhj 2705 16 two two CD cord-005646-xhx9pzhj 2705 17 separate separate JJ cord-005646-xhx9pzhj 2705 18 Imnens Imnens NNPS cord-005646-xhx9pzhj 2705 19 . . . cord-005646-xhx9pzhj 2706 1 DL DL NNP cord-005646-xhx9pzhj 2706 2 - - HYPH cord-005646-xhx9pzhj 2706 3 ETT ETT NNP cord-005646-xhx9pzhj 2706 4 and and CC cord-005646-xhx9pzhj 2706 5 SL SL NNP cord-005646-xhx9pzhj 2706 6 - - HYPH cord-005646-xhx9pzhj 2706 7 ETT ETT NNP cord-005646-xhx9pzhj 2706 8 were be VBD cord-005646-xhx9pzhj 2706 9 randomly randomly RB cord-005646-xhx9pzhj 2706 10 applied apply VBN cord-005646-xhx9pzhj 2706 11 to to IN cord-005646-xhx9pzhj 2706 12 five five CD cord-005646-xhx9pzhj 2706 13 adult adult NN cord-005646-xhx9pzhj 2706 14 paralyzed paralyzed JJ cord-005646-xhx9pzhj 2706 15 rabbits rabbit NNS cord-005646-xhx9pzhj 2706 16 with with IN cord-005646-xhx9pzhj 2706 17 acute acute JJ cord-005646-xhx9pzhj 2706 18 lung lung NN cord-005646-xhx9pzhj 2706 19 injury injury NN cord-005646-xhx9pzhj 2706 20 ( ( -LRB- cord-005646-xhx9pzhj 2706 21 by by IN cord-005646-xhx9pzhj 2706 22 0.1 0.1 CD cord-005646-xhx9pzhj 2706 23 nffkg nffkg NN cord-005646-xhx9pzhj 2706 24 oleic oleic NN cord-005646-xhx9pzhj 2706 25 acid acid NN cord-005646-xhx9pzhj 2706 26 . . . cord-005646-xhx9pzhj 2707 1 iv iv LS cord-005646-xhx9pzhj 2707 2 ) ) -RRB- cord-005646-xhx9pzhj 2707 3 . . . cord-005646-xhx9pzhj 2708 1 A a DT cord-005646-xhx9pzhj 2708 2 Bird Bird NNP cord-005646-xhx9pzhj 2708 3 inter inter NN cord-005646-xhx9pzhj 2708 4 3 3 CD cord-005646-xhx9pzhj 2708 5 vetffttator vetffttator NN cord-005646-xhx9pzhj 2708 6 ( ( -LRB- cord-005646-xhx9pzhj 2708 7 Bird Bird NNP cord-005646-xhx9pzhj 2708 8 products product NNS cord-005646-xhx9pzhj 2708 9 corporation corporation NN cord-005646-xhx9pzhj 2708 10 ) ) -RRB- cord-005646-xhx9pzhj 2708 11 was be VBD cord-005646-xhx9pzhj 2708 12 used use VBN cord-005646-xhx9pzhj 2708 13 for for IN cord-005646-xhx9pzhj 2708 14 time time NN cord-005646-xhx9pzhj 2708 15 - - HYPH cord-005646-xhx9pzhj 2708 16 cycled cycle VBN cord-005646-xhx9pzhj 2708 17 pressure pressure NN cord-005646-xhx9pzhj 2708 18 - - HYPH cord-005646-xhx9pzhj 2708 19 limited limit VBN cord-005646-xhx9pzhj 2708 20 ventilation ventilation NN cord-005646-xhx9pzhj 2708 21 at at IN cord-005646-xhx9pzhj 2708 22 40 40 CD cord-005646-xhx9pzhj 2708 23 / / SYM cord-005646-xhx9pzhj 2708 24 min min NN cord-005646-xhx9pzhj 2708 25 of of IN cord-005646-xhx9pzhj 2708 26 respiratory respiratory JJ cord-005646-xhx9pzhj 2708 27 rate rate NN cord-005646-xhx9pzhj 2708 28 , , , cord-005646-xhx9pzhj 2708 29 10 10 CD cord-005646-xhx9pzhj 2708 30 ern ern NNP cord-005646-xhx9pzhj 2708 31 H20 H20 NNP cord-005646-xhx9pzhj 2708 32 of of IN cord-005646-xhx9pzhj 2708 33 peak peak NN cord-005646-xhx9pzhj 2708 34 i_~piratory i_~piratory NNP cord-005646-xhx9pzhj 2708 35 pressure pressure NN cord-005646-xhx9pzhj 2708 36 , , , cord-005646-xhx9pzhj 2708 37 l l NN cord-005646-xhx9pzhj 2708 38 : : : cord-005646-xhx9pzhj 2708 39 1 1 CD cord-005646-xhx9pzhj 2708 40 of of IN cord-005646-xhx9pzhj 2708 41 IrE IrE NNP cord-005646-xhx9pzhj 2708 42 ratio ratio NN cord-005646-xhx9pzhj 2708 43 , , , cord-005646-xhx9pzhj 2708 44 6 6 CD cord-005646-xhx9pzhj 2708 45 LJmin LJmin NNP cord-005646-xhx9pzhj 2708 46 . . . cord-005646-xhx9pzhj 2709 1 of of IN cord-005646-xhx9pzhj 2709 2 flow flow NN cord-005646-xhx9pzhj 2709 3 rate rate NN cord-005646-xhx9pzhj 2709 4 and and CC cord-005646-xhx9pzhj 2709 5 0.21 0.21 CD cord-005646-xhx9pzhj 2709 6 of of IN cord-005646-xhx9pzhj 2709 7 FiCh FiCh NNP cord-005646-xhx9pzhj 2709 8 . . . cord-005646-xhx9pzhj 2710 1 Peak Peak NNP cord-005646-xhx9pzhj 2710 2 inspirntory inspirntory JJ cord-005646-xhx9pzhj 2710 3 pressure pressure NN cord-005646-xhx9pzhj 2710 4 , , , cord-005646-xhx9pzhj 2710 5 mean mean VB cord-005646-xhx9pzhj 2710 6 mrway mrway JJ cord-005646-xhx9pzhj 2710 7 pressure pressure NN cord-005646-xhx9pzhj 2710 8 , , , cord-005646-xhx9pzhj 2710 9 posi6ve posi6ve NNP cord-005646-xhx9pzhj 2710 10 end end NN cord-005646-xhx9pzhj 2710 11 - - HYPH cord-005646-xhx9pzhj 2710 12 expiratory expiratory NN cord-005646-xhx9pzhj 2710 13 pressure pressure NN cord-005646-xhx9pzhj 2710 14 at at IN cord-005646-xhx9pzhj 2710 15 tip tip NN cord-005646-xhx9pzhj 2710 16 of of IN cord-005646-xhx9pzhj 2710 17 ET ET NNP cord-005646-xhx9pzhj 2710 18 - - HYPH cord-005646-xhx9pzhj 2710 19 mbe mbe NNP cord-005646-xhx9pzhj 2710 20 and and CC cord-005646-xhx9pzhj 2710 21 bemodynamics bemodynamics NNP cord-005646-xhx9pzhj 2710 22 were be VBD cord-005646-xhx9pzhj 2710 23 measured measure VBN cord-005646-xhx9pzhj 2710 24 and and CC cord-005646-xhx9pzhj 2710 25 recorded record VBD cord-005646-xhx9pzhj 2710 26 continuously continuously RB cord-005646-xhx9pzhj 2710 27 . . . cord-005646-xhx9pzhj 2711 1 Arterial arterial JJ cord-005646-xhx9pzhj 2711 2 blood blood NN cord-005646-xhx9pzhj 2711 3 and and CC cord-005646-xhx9pzhj 2711 4 expired expire VBN cord-005646-xhx9pzhj 2711 5 gas gas NN cord-005646-xhx9pzhj 2711 6 were be VBD cord-005646-xhx9pzhj 2711 7 measured measure VBN cord-005646-xhx9pzhj 2712 1 ~by ~by NNP cord-005646-xhx9pzhj 2713 1 AVL AVL NNP cord-005646-xhx9pzhj 2713 2 993 993 CD cord-005646-xhx9pzhj 2713 3 blood blood NN cord-005646-xhx9pzhj 2713 4 gas gas NN cord-005646-xhx9pzhj 2713 5 analyzer analyzer NN cord-005646-xhx9pzhj 2713 6 ) ) -RRB- cord-005646-xhx9pzhj 2713 7 after after IN cord-005646-xhx9pzhj 2713 8 each each DT cord-005646-xhx9pzhj 2713 9 stabilization stabilization NN cord-005646-xhx9pzhj 2713 10 t.~iod t.~iod NNP cord-005646-xhx9pzhj 2713 11 of of IN cord-005646-xhx9pzhj 2713 12 30 30 CD cord-005646-xhx9pzhj 2713 13 minntes minnte NNS cord-005646-xhx9pzhj 2713 14 . . . cord-005646-xhx9pzhj 2714 1 _ _ NNP cord-005646-xhx9pzhj 2714 2 Analysis Analysis NNP cord-005646-xhx9pzhj 2714 3 w w NNP cord-005646-xhx9pzhj 2714 4 ~ ~ NFP cord-005646-xhx9pzhj 2714 5 as as IN cord-005646-xhx9pzhj 2714 6 by by IN cord-005646-xhx9pzhj 2714 7 prated prated NNP cord-005646-xhx9pzhj 2714 8 t t NNP cord-005646-xhx9pzhj 2714 9 test test NN cord-005646-xhx9pzhj 2714 10 . . . cord-005646-xhx9pzhj 2715 1 Result result NN cord-005646-xhx9pzhj 2715 2 : : : cord-005646-xhx9pzhj 2716 1 DL DL NNP cord-005646-xhx9pzhj 2716 2 - - HYPH cord-005646-xhx9pzhj 2716 3 ETT ett NN cord-005646-xhx9pzhj 2716 4 acaltety acaltety NN cord-005646-xhx9pzhj 2716 5 improve improve VB cord-005646-xhx9pzhj 2716 6 COs COs NNP cord-005646-xhx9pzhj 2716 7 removal removal NN cord-005646-xhx9pzhj 2716 8 at at IN cord-005646-xhx9pzhj 2716 9 all all RB cord-005646-xhx9pzhj 2716 10 ammaN. ammaN. NNP cord-005646-xhx9pzhj 2716 11 Pa(?Oz Pa(?Oz NNP cord-005646-xhx9pzhj 2716 12 was be VBD cord-005646-xhx9pzhj 2716 13 decreased decrease VBN cord-005646-xhx9pzhj 2716 14 by by IN cord-005646-xhx9pzhj 2716 15 t0.6+_t.5 t0.6+_t.5 ADD cord-005646-xhx9pzhj 2716 16 ( ( -LRB- cord-005646-xhx9pzhj 2716 17 p<0.0l p<0.0l NNP cord-005646-xhx9pzhj 2716 18 ) ) -RRB- cord-005646-xhx9pzhj 2716 19 and and CC cord-005646-xhx9pzhj 2716 20 physiologic physiologic JJ cord-005646-xhx9pzhj 2716 21 dead dead JJ cord-005646-xhx9pzhj 2716 22 space space NN cord-005646-xhx9pzhj 2716 23 fraction fraction NN cord-005646-xhx9pzhj 2717 1 ( ( -LRB- cord-005646-xhx9pzhj 2717 2 V V NNP cord-005646-xhx9pzhj 2717 3 ~ ~ CD cord-005646-xhx9pzhj 2717 4 zVT zVT '' cord-005646-xhx9pzhj 2717 5 ) ) -RRB- cord-005646-xhx9pzhj 2717 6 reduced reduce VBN cord-005646-xhx9pzhj 2717 7 by by IN cord-005646-xhx9pzhj 2717 8 22 22 CD cord-005646-xhx9pzhj 2717 9 % % NN cord-005646-xhx9pzhj 2717 10 + + CC cord-005646-xhx9pzhj 2717 11 -1.8 -1.8 CD cord-005646-xhx9pzhj 2717 12 % % NN cord-005646-xhx9pzhj 2717 13 ( ( -LRB- cord-005646-xhx9pzhj 2717 14 p<0.0 p<0.0 NNP cord-005646-xhx9pzhj 2717 15 t t NN cord-005646-xhx9pzhj 2717 16 ) ) -RRB- cord-005646-xhx9pzhj 2717 17 , , , cord-005646-xhx9pzhj 2717 18 compared compare VBN cord-005646-xhx9pzhj 2717 19 with with IN cord-005646-xhx9pzhj 2717 20 DL DL NNP cord-005646-xhx9pzhj 2717 21 - - HYPH cord-005646-xhx9pzhj 2717 22 ETT ett NN cord-005646-xhx9pzhj 2717 23 . . . cord-005646-xhx9pzhj 2718 1 There there EX cord-005646-xhx9pzhj 2718 2 were be VBD cord-005646-xhx9pzhj 2718 3 no no DT cord-005646-xhx9pzhj 2718 4 significant significant JJ cord-005646-xhx9pzhj 2718 5 change change NN cord-005646-xhx9pzhj 2718 6 in in IN cord-005646-xhx9pzhj 2718 7 arterial arterial JJ cord-005646-xhx9pzhj 2718 8 oxygenation oxygenation NN cord-005646-xhx9pzhj 2718 9 . . . cord-005646-xhx9pzhj 2719 1 Conelus|on Conelus|on NNP cord-005646-xhx9pzhj 2720 1 : : : cord-005646-xhx9pzhj 2721 1 The the DT cord-005646-xhx9pzhj 2721 2 double double JJ cord-005646-xhx9pzhj 2721 3 - - HYPH cord-005646-xhx9pzhj 2721 4 lumen lumen NN cord-005646-xhx9pzhj 2721 5 two two CD cord-005646-xhx9pzhj 2721 6 - - HYPH cord-005646-xhx9pzhj 2721 7 stage stage NN cord-005646-xhx9pzhj 2721 8 ET ET NNP cord-005646-xhx9pzhj 2721 9 - - HYPH cord-005646-xhx9pzhj 2721 10 tabe tabe NNP cord-005646-xhx9pzhj 2721 11 significantly significantly RB cord-005646-xhx9pzhj 2721 12 increases increase VBZ cord-005646-xhx9pzhj 2721 13 ventilation ventilation NN cord-005646-xhx9pzhj 2721 14 effmiency effmiency NN cord-005646-xhx9pzhj 2721 15 with with IN cord-005646-xhx9pzhj 2721 16 simple simple JJ cord-005646-xhx9pzhj 2721 17 operation operation NN cord-005646-xhx9pzhj 2721 18 in in IN cord-005646-xhx9pzhj 2721 19 rabbits rabbit NNS cord-005646-xhx9pzhj 2721 20 v v LS cord-005646-xhx9pzhj 2721 21 , , , cord-005646-xhx9pzhj 2721 22 ith ith IN cord-005646-xhx9pzhj 2721 23 acute acute JJ cord-005646-xhx9pzhj 2721 24 hmg hmg NNP cord-005646-xhx9pzhj 2721 25 injury injury NN cord-005646-xhx9pzhj 2721 26 , , , cord-005646-xhx9pzhj 2721 27 lts lts NNP cord-005646-xhx9pzhj 2721 28 availability availability NN cord-005646-xhx9pzhj 2721 29 may may MD cord-005646-xhx9pzhj 2721 30 influence influence VB cord-005646-xhx9pzhj 2721 31 future future JJ cord-005646-xhx9pzhj 2721 32 clinical clinical JJ cord-005646-xhx9pzhj 2721 33 management management NN cord-005646-xhx9pzhj 2721 34 of of IN cord-005646-xhx9pzhj 2721 35 ~enNated ~enNated NNP cord-005646-xhx9pzhj 2721 36 patient~. patient~. NNP cord-005646-xhx9pzhj 2722 1 This this DT cord-005646-xhx9pzhj 2722 2 ~muly ~muly NNP cord-005646-xhx9pzhj 2722 3 was be VBD cord-005646-xhx9pzhj 2722 4 fimded fimde VBN cord-005646-xhx9pzhj 2722 5 by by IN cord-005646-xhx9pzhj 2722 6 the the DT cord-005646-xhx9pzhj 2722 7 Science Science NNP cord-005646-xhx9pzhj 2722 8 and and CC cord-005646-xhx9pzhj 2722 9 Technology Technology NNP cord-005646-xhx9pzhj 2722 10 . . . cord-005646-xhx9pzhj 2723 1 CommiUee CommiUee NNP cord-005646-xhx9pzhj 2723 2 of of IN cord-005646-xhx9pzhj 2723 3 Beijing Beijing NNP cord-005646-xhx9pzhj 2723 4 Municipality Municipality NNP cord-005646-xhx9pzhj 2723 5 . . . cord-005646-xhx9pzhj 2724 1 Analis Analis NNP cord-005646-xhx9pzhj 2724 2 of of IN cord-005646-xhx9pzhj 2724 3 hemostasis hemostasis NN cord-005646-xhx9pzhj 2724 4 alterations alteration NNS cord-005646-xhx9pzhj 2724 5 on on IN cord-005646-xhx9pzhj 2724 6 different different JJ cord-005646-xhx9pzhj 2724 7 coagulation coagulation NN cord-005646-xhx9pzhj 2724 8 cascades cascade VBZ cord-005646-xhx9pzhj 2724 9 in in IN cord-005646-xhx9pzhj 2724 10 46 46 CD cord-005646-xhx9pzhj 2724 11 children child NNS cord-005646-xhx9pzhj 2724 12 with with IN cord-005646-xhx9pzhj 2724 13 septic septic JJ cord-005646-xhx9pzhj 2724 14 shock shock NN cord-005646-xhx9pzhj 2725 1 has have VBZ cord-005646-xhx9pzhj 2725 2 shown show VBN cord-005646-xhx9pzhj 2725 3 that that IN cord-005646-xhx9pzhj 2725 4 coagulation coagulation NN cord-005646-xhx9pzhj 2725 5 disorder disorder NN cord-005646-xhx9pzhj 2725 6 character character NN cord-005646-xhx9pzhj 2725 7 is be VBZ cord-005646-xhx9pzhj 2725 8 dependent dependent JJ cord-005646-xhx9pzhj 2725 9 on on IN cord-005646-xhx9pzhj 2725 10 lung lung NN cord-005646-xhx9pzhj 2725 11 affection affection NN cord-005646-xhx9pzhj 2725 12 rate rate NN cord-005646-xhx9pzhj 2725 13 . . . cord-005646-xhx9pzhj 2726 1 The the DT cord-005646-xhx9pzhj 2726 2 initial initial JJ cord-005646-xhx9pzhj 2726 3 manifestation manifestation NN cord-005646-xhx9pzhj 2726 4 of of IN cord-005646-xhx9pzhj 2726 5 the the DT cord-005646-xhx9pzhj 2726 6 respiratory respiratory JJ cord-005646-xhx9pzhj 2726 7 distress distress NN cord-005646-xhx9pzhj 2726 8 - - HYPH cord-005646-xhx9pzhj 2726 9 syndrome syndrome NN cord-005646-xhx9pzhj 2726 10 ( ( -LRB- cord-005646-xhx9pzhj 2726 11 RDS RDS NNP cord-005646-xhx9pzhj 2726 12 ) ) -RRB- cord-005646-xhx9pzhj 2726 13 are be VBP cord-005646-xhx9pzhj 2726 14 characterized characterize VBN cord-005646-xhx9pzhj 2726 15 by by IN cord-005646-xhx9pzhj 2726 16 the the DT cord-005646-xhx9pzhj 2726 17 obvious obvious JJ cord-005646-xhx9pzhj 2726 18 activation activation NN cord-005646-xhx9pzhj 2726 19 of of IN cord-005646-xhx9pzhj 2726 20 blood blood NN cord-005646-xhx9pzhj 2726 21 thrombin thrombin NN cord-005646-xhx9pzhj 2726 22 potential potential NN cord-005646-xhx9pzhj 2726 23 , , , cord-005646-xhx9pzhj 2726 24 moderate moderate JJ cord-005646-xhx9pzhj 2726 25 coagulopathy coagulopathy NN cord-005646-xhx9pzhj 2726 26 and and CC cord-005646-xhx9pzhj 2726 27 not not RB cord-005646-xhx9pzhj 2726 28 sharply sharply RB cord-005646-xhx9pzhj 2726 29 marked mark VBN cord-005646-xhx9pzhj 2726 30 endoteliosis endoteliosis NN cord-005646-xhx9pzhj 2726 31 , , , cord-005646-xhx9pzhj 2726 32 the the DT cord-005646-xhx9pzhj 2726 33 Witlebrand Witlebrand NNP cord-005646-xhx9pzhj 2726 34 's 's POS cord-005646-xhx9pzhj 2726 35 factor factor NN cord-005646-xhx9pzhj 2726 36 ( ( -LRB- cord-005646-xhx9pzhj 2726 37 WF WF NNP cord-005646-xhx9pzhj 2726 38 ) ) -RRB- cord-005646-xhx9pzhj 2726 39 increase increase NN cord-005646-xhx9pzhj 2726 40 tot tot NNP cord-005646-xhx9pzhj 2726 41 140 140 CD cord-005646-xhx9pzhj 2726 42 - - SYM cord-005646-xhx9pzhj 2726 43 220 220 CD cord-005646-xhx9pzhj 2726 44 % % NN cord-005646-xhx9pzhj 2726 45 . . . cord-005646-xhx9pzhj 2727 1 Progress progress VB cord-005646-xhx9pzhj 2727 2 in in IN cord-005646-xhx9pzhj 2727 3 the the DT cord-005646-xhx9pzhj 2727 4 clinical clinical JJ cord-005646-xhx9pzhj 2727 5 picture picture NN cord-005646-xhx9pzhj 2727 6 of of IN cord-005646-xhx9pzhj 2727 7 " " `` cord-005646-xhx9pzhj 2727 8 shock shock NN cord-005646-xhx9pzhj 2727 9 lung lung NN cord-005646-xhx9pzhj 2727 10 " " '' cord-005646-xhx9pzhj 2727 11 leads lead VBZ cord-005646-xhx9pzhj 2727 12 to to IN cord-005646-xhx9pzhj 2727 13 chronometric chronometric NN cord-005646-xhx9pzhj 2727 14 and and CC cord-005646-xhx9pzhj 2727 15 structural structural JJ cord-005646-xhx9pzhj 2727 16 hypocoagulation hypocoagulation NN cord-005646-xhx9pzhj 2727 17 with with IN cord-005646-xhx9pzhj 2727 18 potential potential JJ cord-005646-xhx9pzhj 2727 19 hypercoagulation hypercoagulation NN cord-005646-xhx9pzhj 2727 20 in in IN cord-005646-xhx9pzhj 2727 21 " " `` cord-005646-xhx9pzhj 2727 22 mix mix NN cord-005646-xhx9pzhj 2727 23 - - HYPH cord-005646-xhx9pzhj 2727 24 test test NN cord-005646-xhx9pzhj 2727 25 " " '' cord-005646-xhx9pzhj 2727 26 , , , cord-005646-xhx9pzhj 2727 27 high high JJ cord-005646-xhx9pzhj 2727 28 level level NN cord-005646-xhx9pzhj 2727 29 of of IN cord-005646-xhx9pzhj 2727 30 firbin firbin NNP cord-005646-xhx9pzhj 2727 31 derivative derivative JJ cord-005646-xhx9pzhj 2727 32 , , , cord-005646-xhx9pzhj 2727 33 thrombocytopenia thrombocytopenia JJ cord-005646-xhx9pzhj 2727 34 with with IN cord-005646-xhx9pzhj 2727 35 thrombocytopaty thrombocytopaty NNS cord-005646-xhx9pzhj 2727 36 and and CC cord-005646-xhx9pzhj 2727 37 the the DT cord-005646-xhx9pzhj 2727 38 WF WF NNP cord-005646-xhx9pzhj 2727 39 increase increase NN cord-005646-xhx9pzhj 2727 40 to to IN cord-005646-xhx9pzhj 2727 41 210~315 210~315 CD cord-005646-xhx9pzhj 2727 42 % % NN cord-005646-xhx9pzhj 2727 43 , , , cord-005646-xhx9pzhj 2727 44 Terminal Terminal NNP cord-005646-xhx9pzhj 2727 45 stages stage NNS cord-005646-xhx9pzhj 2727 46 of of IN cord-005646-xhx9pzhj 2727 47 the the DT cord-005646-xhx9pzhj 2727 48 RDS RDS NNP cord-005646-xhx9pzhj 2727 49 , , , cord-005646-xhx9pzhj 2727 50 as as IN cord-005646-xhx9pzhj 2727 51 a a DT cord-005646-xhx9pzhj 2727 52 rule rule NN cord-005646-xhx9pzhj 2727 53 , , , cord-005646-xhx9pzhj 2727 54 are be VBP cord-005646-xhx9pzhj 2727 55 characterized characterize VBN cord-005646-xhx9pzhj 2727 56 by by IN cord-005646-xhx9pzhj 2727 57 potential potential JJ cord-005646-xhx9pzhj 2727 58 hypercoaguletion hypercoaguletion NN cord-005646-xhx9pzhj 2727 59 absense absense NN cord-005646-xhx9pzhj 2727 60 , , , cord-005646-xhx9pzhj 2727 61 depletion depletion NN cord-005646-xhx9pzhj 2727 62 of of IN cord-005646-xhx9pzhj 2727 63 AT at NN cord-005646-xhx9pzhj 2727 64 - - HYPH cord-005646-xhx9pzhj 2727 65 lit light VBN cord-005646-xhx9pzhj 2727 66 and and CC cord-005646-xhx9pzhj 2727 67 plasminogen plasminogen NN cord-005646-xhx9pzhj 2727 68 , , , cord-005646-xhx9pzhj 2727 69 prevalence prevalence NN cord-005646-xhx9pzhj 2727 70 of of IN cord-005646-xhx9pzhj 2727 71 antithrombin antithrombin NN cord-005646-xhx9pzhj 2727 72 and and CC cord-005646-xhx9pzhj 2727 73 antiaggregating antiaggregating NN cord-005646-xhx9pzhj 2727 74 activity activity NN cord-005646-xhx9pzhj 2727 75 , , , cord-005646-xhx9pzhj 2727 76 obvious obvious JJ cord-005646-xhx9pzhj 2727 77 endoteliosis endoteliosis NN cord-005646-xhx9pzhj 2727 78 ( ( -LRB- cord-005646-xhx9pzhj 2727 79 the the DT cord-005646-xhx9pzhj 2727 80 WF WF NNP cord-005646-xhx9pzhj 2727 81 to to IN cord-005646-xhx9pzhj 2727 82 increase250 increase250 NNP cord-005646-xhx9pzhj 2727 83 - - HYPH cord-005646-xhx9pzhj 2727 84 540 540 CD cord-005646-xhx9pzhj 2727 85 % % NN cord-005646-xhx9pzhj 2727 86 ) ) -RRB- cord-005646-xhx9pzhj 2727 87 . . . cord-005646-xhx9pzhj 2728 1 The the DT cord-005646-xhx9pzhj 2728 2 arteriowenous arteriowenous JJ cord-005646-xhx9pzhj 2728 3 difference difference NN cord-005646-xhx9pzhj 2728 4 according accord VBG cord-005646-xhx9pzhj 2728 5 to to IN cord-005646-xhx9pzhj 2728 6 index index NN cord-005646-xhx9pzhj 2728 7 of of IN cord-005646-xhx9pzhj 2728 8 the the DT cord-005646-xhx9pzhj 2728 9 thromboelastography thromboelastography NNP cord-005646-xhx9pzhj 2728 10 ( ( -LRB- cord-005646-xhx9pzhj 2728 11 TEG TEG NNP cord-005646-xhx9pzhj 2728 12 ) ) -RRB- cord-005646-xhx9pzhj 2728 13 in in IN cord-005646-xhx9pzhj 2728 14 the the DT cord-005646-xhx9pzhj 2728 15 RDS RDS NNP cord-005646-xhx9pzhj 2728 16 Ill Ill NNP cord-005646-xhx9pzhj 2728 17 - - HYPH cord-005646-xhx9pzhj 2728 18 IV IV NNP cord-005646-xhx9pzhj 2728 19 rates rate NNS cord-005646-xhx9pzhj 2728 20 was be VBD cord-005646-xhx9pzhj 2728 21 69,8 69,8 CD cord-005646-xhx9pzhj 2728 22 % % NN cord-005646-xhx9pzhj 2728 23 less less JJR cord-005646-xhx9pzhj 2728 24 than than IN cord-005646-xhx9pzhj 2728 25 in in IN cord-005646-xhx9pzhj 2728 26 the the DT cord-005646-xhx9pzhj 2728 27 1 1 CD cord-005646-xhx9pzhj 2728 28 - - SYM cord-005646-xhx9pzhj 2728 29 11 11 CD cord-005646-xhx9pzhj 2728 30 rates rate NNS cord-005646-xhx9pzhj 2728 31 , , , cord-005646-xhx9pzhj 2728 32 Disorder disorder NN cord-005646-xhx9pzhj 2728 33 of of IN cord-005646-xhx9pzhj 2728 34 lung lung NN cord-005646-xhx9pzhj 2728 35 filtering filtering NN cord-005646-xhx9pzhj 2728 36 ability ability NN cord-005646-xhx9pzhj 2728 37 in in IN cord-005646-xhx9pzhj 2728 38 severe severe JJ cord-005646-xhx9pzhj 2728 39 RDS RDS NNP cord-005646-xhx9pzhj 2728 40 is be VBZ cord-005646-xhx9pzhj 2728 41 confimed confime VBN cord-005646-xhx9pzhj 2728 42 also also RB cord-005646-xhx9pzhj 2728 43 by by IN cord-005646-xhx9pzhj 2728 44 minimal minimal JJ cord-005646-xhx9pzhj 2728 45 arterio arterio NN cord-005646-xhx9pzhj 2728 46 - - HYPH cord-005646-xhx9pzhj 2728 47 venous venous JJ cord-005646-xhx9pzhj 2728 48 difference difference NN cord-005646-xhx9pzhj 2728 49 of of IN cord-005646-xhx9pzhj 2728 50 activated activate VBN cord-005646-xhx9pzhj 2728 51 euglobulin euglobulin NNP cord-005646-xhx9pzhj 2728 52 lyses lyse VBZ cord-005646-xhx9pzhj 2728 53 ( ( -LRB- cord-005646-xhx9pzhj 2728 54 AEL AEL NNP cord-005646-xhx9pzhj 2728 55 ) ) -RRB- cord-005646-xhx9pzhj 2728 56 in in IN cord-005646-xhx9pzhj 2728 57 children child NNS cord-005646-xhx9pzhj 2728 58 with with IN cord-005646-xhx9pzhj 2728 59 the the DT cord-005646-xhx9pzhj 2728 60 RDS RDS NNP cord-005646-xhx9pzhj 2728 61 Ill Ill NNP cord-005646-xhx9pzhj 2728 62 - - HYPH cord-005646-xhx9pzhj 2728 63 IV IV NNP cord-005646-xhx9pzhj 2728 64 rates rate NNS cord-005646-xhx9pzhj 2728 65 is be VBZ cord-005646-xhx9pzhj 2728 66 only only RB cord-005646-xhx9pzhj 2728 67 11,4 11,4 CD cord-005646-xhx9pzhj 2728 68 % % NN cord-005646-xhx9pzhj 2728 69 , , , cord-005646-xhx9pzhj 2728 70 while while IN cord-005646-xhx9pzhj 2728 71 the the DT cord-005646-xhx9pzhj 2728 72 patients patient NNS cord-005646-xhx9pzhj 2728 73 whit whit NNP cord-005646-xhx9pzhj 2729 1 RDS RDS NNP cord-005646-xhx9pzhj 2729 2 I I NNP cord-005646-xhx9pzhj 2729 3 - - HYPH cord-005646-xhx9pzhj 2729 4 I1 i1 NN cord-005646-xhx9pzhj 2729 5 rates rate NNS cord-005646-xhx9pzhj 2729 6 have have VBP cord-005646-xhx9pzhj 2729 7 the the DT cord-005646-xhx9pzhj 2729 8 AEL AEL NNP cord-005646-xhx9pzhj 2729 9 - - HYPH cord-005646-xhx9pzhj 2729 10 activity activity NN cord-005646-xhx9pzhj 2729 11 in in IN cord-005646-xhx9pzhj 2729 12 arterial arterial JJ cord-005646-xhx9pzhj 2729 13 blood blood NN cord-005646-xhx9pzhj 2729 14 2,1 2,1 CD cord-005646-xhx9pzhj 2729 15 times time NNS cord-005646-xhx9pzhj 2729 16 as as RB cord-005646-xhx9pzhj 2729 17 much much JJ cord-005646-xhx9pzhj 2729 18 than than IN cord-005646-xhx9pzhj 2729 19 in in IN cord-005646-xhx9pzhj 2729 20 venous venous JJ cord-005646-xhx9pzhj 2729 21 blood blood NN cord-005646-xhx9pzhj 2729 22 . . . cord-005646-xhx9pzhj 2730 1 The the DT cord-005646-xhx9pzhj 2730 2 use use NN cord-005646-xhx9pzhj 2730 3 of of IN cord-005646-xhx9pzhj 2730 4 then then RB cord-005646-xhx9pzhj 2730 5 allows allow VBZ cord-005646-xhx9pzhj 2730 6 to to TO cord-005646-xhx9pzhj 2730 7 determine determine VB cord-005646-xhx9pzhj 2730 8 the the DT cord-005646-xhx9pzhj 2730 9 potential potential JJ cord-005646-xhx9pzhj 2730 10 hypercoagulation hypercoagulation NN cord-005646-xhx9pzhj 2730 11 rate rate NN cord-005646-xhx9pzhj 2730 12 , , , cord-005646-xhx9pzhj 2730 13 the the DT cord-005646-xhx9pzhj 2730 14 AT AT NNP cord-005646-xhx9pzhj 2730 15 - - HYPH cord-005646-xhx9pzhj 2730 16 Ill Ill NNP cord-005646-xhx9pzhj 2730 17 level level NN cord-005646-xhx9pzhj 2730 18 and and CC cord-005646-xhx9pzhj 2730 19 fibrinogen fibrinogen NN cord-005646-xhx9pzhj 2730 20 quantity quantity NN cord-005646-xhx9pzhj 2730 21 during during IN cord-005646-xhx9pzhj 2730 22 the the DT cord-005646-xhx9pzhj 2730 23 anticoagulant anticoagulant JJ cord-005646-xhx9pzhj 2730 24 therapy therapy NN cord-005646-xhx9pzhj 2730 25 and and CC cord-005646-xhx9pzhj 2730 26 also also RB cord-005646-xhx9pzhj 2730 27 the the DT cord-005646-xhx9pzhj 2730 28 character character NN cord-005646-xhx9pzhj 2730 29 of of IN cord-005646-xhx9pzhj 2730 30 the the DT cord-005646-xhx9pzhj 2730 31 X x NN cord-005646-xhx9pzhj 2730 32 - - NN cord-005646-xhx9pzhj 2730 33 factor factor NN cord-005646-xhx9pzhj 2730 34 activation activation NN cord-005646-xhx9pzhj 2730 35 and and CC cord-005646-xhx9pzhj 2730 36 thrombocytic thrombocytic JJ cord-005646-xhx9pzhj 2730 37 hemostasis hemostasis NN cord-005646-xhx9pzhj 2730 38 . . . cord-005646-xhx9pzhj 2731 1 The the DT cord-005646-xhx9pzhj 2731 2 effective effective JJ cord-005646-xhx9pzhj 2731 3 therapy therapy NN cord-005646-xhx9pzhj 2731 4 component component NN cord-005646-xhx9pzhj 2731 5 of of IN cord-005646-xhx9pzhj 2731 6 septic septic JJ cord-005646-xhx9pzhj 2731 7 genesis genesis NN cord-005646-xhx9pzhj 2731 8 RDS RDS NNP cord-005646-xhx9pzhj 2731 9 in in IN cord-005646-xhx9pzhj 2731 10 children child NNS cord-005646-xhx9pzhj 2731 11 is be VBZ cord-005646-xhx9pzhj 2731 12 the the DT cord-005646-xhx9pzhj 2731 13 controled control VBN cord-005646-xhx9pzhj 2731 14 coagulation coagulation NN cord-005646-xhx9pzhj 2731 15 method method NN cord-005646-xhx9pzhj 2731 16 with with IN cord-005646-xhx9pzhj 2731 17 the the DT cord-005646-xhx9pzhj 2731 18 use use NN cord-005646-xhx9pzhj 2731 19 of of IN cord-005646-xhx9pzhj 2731 20 the the DT cord-005646-xhx9pzhj 2731 21 individual individual JJ cord-005646-xhx9pzhj 2731 22 selected select VBN cord-005646-xhx9pzhj 2731 23 heparin heparin JJ cord-005646-xhx9pzhj 2731 24 doses dose NNS cord-005646-xhx9pzhj 2731 25 in in IN cord-005646-xhx9pzhj 2731 26 according accord VBG cord-005646-xhx9pzhj 2731 27 to to IN cord-005646-xhx9pzhj 2731 28 desagregants desagregants NNP cord-005646-xhx9pzhj 2731 29 , , , cord-005646-xhx9pzhj 2731 30 kryoplasma kryoplasma NNP cord-005646-xhx9pzhj 2731 31 , , , cord-005646-xhx9pzhj 2731 32 proteolisis proteolisis NNP cord-005646-xhx9pzhj 2731 33 inhibitors inhibitor NNS cord-005646-xhx9pzhj 2731 34 and and CC cord-005646-xhx9pzhj 2731 35 trombolytics trombolytic NNS cord-005646-xhx9pzhj 2731 36 . . . cord-005646-xhx9pzhj 2732 1 It -PRON- PRP cord-005646-xhx9pzhj 2732 2 is be VBZ cord-005646-xhx9pzhj 2732 3 necessary necessary JJ cord-005646-xhx9pzhj 2732 4 to to TO cord-005646-xhx9pzhj 2732 5 avoid avoid VB cord-005646-xhx9pzhj 2732 6 the the DT cord-005646-xhx9pzhj 2732 7 heparintherapy heparintherapy NN cord-005646-xhx9pzhj 2732 8 for for IN cord-005646-xhx9pzhj 2732 9 children child NNS cord-005646-xhx9pzhj 2732 10 with with IN cord-005646-xhx9pzhj 2732 11 the the DT cord-005646-xhx9pzhj 2732 12 RDS RDS NNP cord-005646-xhx9pzhj 2732 13 complicated complicate VBN cord-005646-xhx9pzhj 2732 14 with with IN cord-005646-xhx9pzhj 2732 15 producting producte VBG cord-005646-xhx9pzhj 2732 16 coagulopaties coagulopatie NNS cord-005646-xhx9pzhj 2732 17 and and CC cord-005646-xhx9pzhj 2732 18 termal termal NN cord-005646-xhx9pzhj 2732 19 phases phase NNS cord-005646-xhx9pzhj 2732 20 of of IN cord-005646-xhx9pzhj 2732 21 blood blood NN cord-005646-xhx9pzhj 2732 22 disseminated disseminate VBN cord-005646-xhx9pzhj 2732 23 intravascular intravascular JJ cord-005646-xhx9pzhj 2732 24 coagulation coagulation NN cord-005646-xhx9pzhj 2732 25 ( ( -LRB- cord-005646-xhx9pzhj 2732 26 DIC DIC NNP cord-005646-xhx9pzhj 2732 27 ) ) -RRB- cord-005646-xhx9pzhj 2732 28 . . . cord-005646-xhx9pzhj 2733 1 Bronchoseopy Bronchoseopy NNP cord-005646-xhx9pzhj 2733 2 has have VBZ cord-005646-xhx9pzhj 2733 3 been be VBN cord-005646-xhx9pzhj 2733 4 used use VBN cord-005646-xhx9pzhj 2733 5 for for IN cord-005646-xhx9pzhj 2733 6 evaluation evaluation NN cord-005646-xhx9pzhj 2733 7 of of IN cord-005646-xhx9pzhj 2733 8 the the DT cord-005646-xhx9pzhj 2733 9 potential potential JJ cord-005646-xhx9pzhj 2733 10 problems problem NNS cord-005646-xhx9pzhj 2733 11 of of IN cord-005646-xhx9pzhj 2733 12 the the DT cord-005646-xhx9pzhj 2733 13 airways airway NNS cord-005646-xhx9pzhj 2733 14 and and CC cord-005646-xhx9pzhj 2733 15 for for IN cord-005646-xhx9pzhj 2733 16 investigation investigation NN cord-005646-xhx9pzhj 2733 17 the the DT cord-005646-xhx9pzhj 2733 18 bronchial bronchial JJ cord-005646-xhx9pzhj 2733 19 specimens specimen NNS cord-005646-xhx9pzhj 2733 20 for for IN cord-005646-xhx9pzhj 2733 21 diagnostic diagnostic JJ cord-005646-xhx9pzhj 2733 22 purposes purpose NNS cord-005646-xhx9pzhj 2733 23 . . . cord-005646-xhx9pzhj 2734 1 Regent Regent NNP cord-005646-xhx9pzhj 2734 2 technical technical JJ cord-005646-xhx9pzhj 2734 3 advances advance NNS cord-005646-xhx9pzhj 2734 4 result result VBP cord-005646-xhx9pzhj 2734 5 in in IN cord-005646-xhx9pzhj 2734 6 performing perform VBG cord-005646-xhx9pzhj 2734 7 this this DT cord-005646-xhx9pzhj 2734 8 procedure procedure NN cord-005646-xhx9pzhj 2734 9 at at IN cord-005646-xhx9pzhj 2734 10 the the DT cord-005646-xhx9pzhj 2734 11 bedside bedside NN cord-005646-xhx9pzhj 2734 12 manner manner NN cord-005646-xhx9pzhj 2734 13 and and CC cord-005646-xhx9pzhj 2734 14 in in IN cord-005646-xhx9pzhj 2734 15 critically critically RB cord-005646-xhx9pzhj 2734 16 ill ill JJ cord-005646-xhx9pzhj 2734 17 patients patient NNS cord-005646-xhx9pzhj 2734 18 . . . cord-005646-xhx9pzhj 2735 1 We -PRON- PRP cord-005646-xhx9pzhj 2735 2 have have VBP cord-005646-xhx9pzhj 2735 3 performed perform VBN cord-005646-xhx9pzhj 2735 4 150 150 CD cord-005646-xhx9pzhj 2735 5 hronehoaeopy hronehoaeopy NN cord-005646-xhx9pzhj 2735 6 during during IN cord-005646-xhx9pzhj 2735 7 last last JJ cord-005646-xhx9pzhj 2735 8 three three CD cord-005646-xhx9pzhj 2735 9 years year NNS cord-005646-xhx9pzhj 2735 10 on on IN cord-005646-xhx9pzhj 2735 11 1362 1362 CD cord-005646-xhx9pzhj 2735 12 pediatric pediatric JJ cord-005646-xhx9pzhj 2735 13 patients patient NNS cord-005646-xhx9pzhj 2735 14 with with IN cord-005646-xhx9pzhj 2735 15 respiratory respiratory JJ cord-005646-xhx9pzhj 2735 16 problems problem NNS cord-005646-xhx9pzhj 2735 17 , , , cord-005646-xhx9pzhj 2735 18 In in IN cord-005646-xhx9pzhj 2735 19 90 90 CD cord-005646-xhx9pzhj 2735 20 % % NN cord-005646-xhx9pzhj 2735 21 of of IN cord-005646-xhx9pzhj 2735 22 cases case NNS cord-005646-xhx9pzhj 2735 23 the the DT cord-005646-xhx9pzhj 2735 24 opentube opentube NN cord-005646-xhx9pzhj 2735 25 hroneh0seopy hroneh0seopy NNP cord-005646-xhx9pzhj 2735 26 was be VBD cord-005646-xhx9pzhj 2735 27 performed perform VBN cord-005646-xhx9pzhj 2735 28 ( ( -LRB- cord-005646-xhx9pzhj 2735 29 for for IN cord-005646-xhx9pzhj 2735 30 diagnostic diagnostic JJ cord-005646-xhx9pzhj 2735 31 as as RB cord-005646-xhx9pzhj 2735 32 well well RB cord-005646-xhx9pzhj 2735 33 as as IN cord-005646-xhx9pzhj 2735 34 for for IN cord-005646-xhx9pzhj 2735 35 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2735 36 reasons reason NNS cord-005646-xhx9pzhj 2735 37 ) ) -RRB- cord-005646-xhx9pzhj 2735 38 and and CC cord-005646-xhx9pzhj 2735 39 collected collect VBD cord-005646-xhx9pzhj 2735 40 secretions secretion NNS cord-005646-xhx9pzhj 2735 41 or or CC cord-005646-xhx9pzhj 2735 42 bioptic bioptic JJ cord-005646-xhx9pzhj 2735 43 material material NN cord-005646-xhx9pzhj 2735 44 were be VBD cord-005646-xhx9pzhj 2735 45 examined examine VBN cord-005646-xhx9pzhj 2735 46 . . . cord-005646-xhx9pzhj 2736 1 The the DT cord-005646-xhx9pzhj 2736 2 indieatiuns indieatiun NNS cord-005646-xhx9pzhj 2736 3 were be VBD cord-005646-xhx9pzhj 2736 4 : : : cord-005646-xhx9pzhj 2736 5 acute acute JJ cord-005646-xhx9pzhj 2736 6 upper upper JJ cord-005646-xhx9pzhj 2736 7 respiratory respiratory JJ cord-005646-xhx9pzhj 2736 8 problems problem NNS cord-005646-xhx9pzhj 2736 9 , , , cord-005646-xhx9pzhj 2736 10 chronic chronic JJ cord-005646-xhx9pzhj 2736 11 wheezing wheezing NN cord-005646-xhx9pzhj 2736 12 , , , cord-005646-xhx9pzhj 2736 13 inspiratory inspiratory JJ cord-005646-xhx9pzhj 2736 14 strider strider NN cord-005646-xhx9pzhj 2736 15 , , , cord-005646-xhx9pzhj 2736 16 tracheal tracheal JJ cord-005646-xhx9pzhj 2736 17 or or CC cord-005646-xhx9pzhj 2736 18 bronchial bronchial JJ cord-005646-xhx9pzhj 2736 19 bleeding bleeding NN cord-005646-xhx9pzhj 2736 20 , , , cord-005646-xhx9pzhj 2736 21 chronic chronic JJ cord-005646-xhx9pzhj 2736 22 eongh eongh NN cord-005646-xhx9pzhj 2736 23 , , , cord-005646-xhx9pzhj 2736 24 retractable retractable JJ cord-005646-xhx9pzhj 2736 25 atelectssis atelectssis NN cord-005646-xhx9pzhj 2736 26 , , , cord-005646-xhx9pzhj 2736 27 severe severe JJ cord-005646-xhx9pzhj 2736 28 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2736 29 infections infection NNS cord-005646-xhx9pzhj 2736 30 , , , cord-005646-xhx9pzhj 2736 31 lymph lymph NN cord-005646-xhx9pzhj 2736 32 node node NN cord-005646-xhx9pzhj 2736 33 perforation perforation NN cord-005646-xhx9pzhj 2736 34 in in IN cord-005646-xhx9pzhj 2736 35 lung lung NN cord-005646-xhx9pzhj 2736 36 tuberculosis tuberculosis NN cord-005646-xhx9pzhj 2736 37 and and CC cord-005646-xhx9pzhj 2736 38 soquells soquell NNS cord-005646-xhx9pzhj 2736 39 like like IN cord-005646-xhx9pzhj 2736 40 bronehiectssis bronehiectssis NNP cord-005646-xhx9pzhj 2736 41 and and CC cord-005646-xhx9pzhj 2736 42 fibrosis fibrosis NN cord-005646-xhx9pzhj 2736 43 . . . cord-005646-xhx9pzhj 2737 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 2737 2 results result NNS cord-005646-xhx9pzhj 2737 3 were be VBD cord-005646-xhx9pzhj 2737 4 : : : cord-005646-xhx9pzhj 2737 5 anatomical anatomical JJ cord-005646-xhx9pzhj 2737 6 malformations malformation NNS cord-005646-xhx9pzhj 2737 7 in in IN cord-005646-xhx9pzhj 2737 8 10 10 CD cord-005646-xhx9pzhj 2737 9 % % NN cord-005646-xhx9pzhj 2737 10 , , , cord-005646-xhx9pzhj 2737 11 mueosal mueosal NN cord-005646-xhx9pzhj 2737 12 oedema oedema NN cord-005646-xhx9pzhj 2737 13 with with IN cord-005646-xhx9pzhj 2737 14 chronic chronic JJ cord-005646-xhx9pzhj 2737 15 inflammation inflammation NN cord-005646-xhx9pzhj 2737 16 and and CC cord-005646-xhx9pzhj 2737 17 thick thick JJ cord-005646-xhx9pzhj 2737 18 secretions secretion NNS cord-005646-xhx9pzhj 2737 19 in in IN cord-005646-xhx9pzhj 2737 20 56 56 CD cord-005646-xhx9pzhj 2737 21 % % NN cord-005646-xhx9pzhj 2737 22 , , , cord-005646-xhx9pzhj 2737 23 easuos easuos NN cord-005646-xhx9pzhj 2737 24 masses masse NNS cord-005646-xhx9pzhj 2737 25 in in IN cord-005646-xhx9pzhj 2737 26 11 11 CD cord-005646-xhx9pzhj 2737 27 % % NN cord-005646-xhx9pzhj 2737 28 , , , cord-005646-xhx9pzhj 2737 29 granulation granulation NN cord-005646-xhx9pzhj 2737 30 tissue tissue NN cord-005646-xhx9pzhj 2737 31 and and CC cord-005646-xhx9pzhj 2737 32 purulent purulent JJ cord-005646-xhx9pzhj 2737 33 secretions secretion NNS cord-005646-xhx9pzhj 2737 34 in in IN cord-005646-xhx9pzhj 2737 35 foreign foreign JJ cord-005646-xhx9pzhj 2737 36 bodies body NNS cord-005646-xhx9pzhj 2737 37 and and CC cord-005646-xhx9pzhj 2737 38 bronehieetasis bronehieetasis NN cord-005646-xhx9pzhj 2737 39 in in IN cord-005646-xhx9pzhj 2737 40 16 16 CD cord-005646-xhx9pzhj 2737 41 % % NN cord-005646-xhx9pzhj 2737 42 , , , cord-005646-xhx9pzhj 2737 43 and and CC cord-005646-xhx9pzhj 2737 44 only only RB cord-005646-xhx9pzhj 2737 45 7 7 CD cord-005646-xhx9pzhj 2737 46 % % NN cord-005646-xhx9pzhj 2737 47 of of IN cord-005646-xhx9pzhj 2737 48 eases ease NNS cord-005646-xhx9pzhj 2737 49 were be VBD cord-005646-xhx9pzhj 2737 50 normal normal JJ cord-005646-xhx9pzhj 2737 51 finding finding NN cord-005646-xhx9pzhj 2737 52 . . . cord-005646-xhx9pzhj 2738 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 2738 2 eXlXdenees eXlXdenees NNP cord-005646-xhx9pzhj 2738 3 pointed point VBD cord-005646-xhx9pzhj 2738 4 that that IN cord-005646-xhx9pzhj 2738 5 this this DT cord-005646-xhx9pzhj 2738 6 invasive invasive JJ cord-005646-xhx9pzhj 2738 7 procedure procedure NN cord-005646-xhx9pzhj 2738 8 in in IN cord-005646-xhx9pzhj 2738 9 carefully carefully RB cord-005646-xhx9pzhj 2738 10 selected select VBN cord-005646-xhx9pzhj 2738 11 patients patient NNS cord-005646-xhx9pzhj 2738 12 has have VBZ cord-005646-xhx9pzhj 2738 13 important important JJ cord-005646-xhx9pzhj 2738 14 role role NN cord-005646-xhx9pzhj 2738 15 in in IN cord-005646-xhx9pzhj 2738 16 establishing establish VBG cord-005646-xhx9pzhj 2738 17 the the DT cord-005646-xhx9pzhj 2738 18 diagnosis diagnosis NN cord-005646-xhx9pzhj 2738 19 and and CC cord-005646-xhx9pzhj 2738 20 in in IN cord-005646-xhx9pzhj 2738 21 the- the- DT cord-005646-xhx9pzhj 2738 22 Introduction introduction NN cord-005646-xhx9pzhj 2738 23 : : : cord-005646-xhx9pzhj 2738 24 TBG TBG NNP cord-005646-xhx9pzhj 2738 25 has have VBZ cord-005646-xhx9pzhj 2738 26 been be VBN cord-005646-xhx9pzhj 2738 27 a a DT cord-005646-xhx9pzhj 2738 28 useful useful JJ cord-005646-xhx9pzhj 2738 29 investigation investigation NN cord-005646-xhx9pzhj 2738 30 in in IN cord-005646-xhx9pzhj 2738 31 the the DT cord-005646-xhx9pzhj 2738 32 management management NN cord-005646-xhx9pzhj 2738 33 of of IN cord-005646-xhx9pzhj 2738 34 ventilator ventilator NN cord-005646-xhx9pzhj 2738 35 - - HYPH cord-005646-xhx9pzhj 2738 36 dependent dependent JJ cord-005646-xhx9pzhj 2738 37 infants infant NNS cord-005646-xhx9pzhj 2738 38 in in IN cord-005646-xhx9pzhj 2738 39 our -PRON- PRP$ cord-005646-xhx9pzhj 2738 40 experience experience NN cord-005646-xhx9pzhj 2738 41 . . . cord-005646-xhx9pzhj 2739 1 One one CD cord-005646-xhx9pzhj 2739 2 ml ml NN cord-005646-xhx9pzhj 2739 3 of of IN cord-005646-xhx9pzhj 2739 4 contrast contrast NN cord-005646-xhx9pzhj 2739 5 was be VBD cord-005646-xhx9pzhj 2739 6 hand hand NN cord-005646-xhx9pzhj 2739 7 ventilated ventilate VBN cord-005646-xhx9pzhj 2739 8 into into IN cord-005646-xhx9pzhj 2739 9 the the DT cord-005646-xhx9pzhj 2739 10 respiratory respiratory JJ cord-005646-xhx9pzhj 2739 11 tree tree NN cord-005646-xhx9pzhj 2739 12 via via IN cord-005646-xhx9pzhj 2739 13 their -PRON- PRP$ cord-005646-xhx9pzhj 2739 14 nasotracheal nasotracheal JJ cord-005646-xhx9pzhj 2739 15 tubes tube NNS cord-005646-xhx9pzhj 2739 16 and and CC cord-005646-xhx9pzhj 2739 17 their -PRON- PRP$ cord-005646-xhx9pzhj 2739 18 anatomy anatomy NN cord-005646-xhx9pzhj 2739 19 and and CC cord-005646-xhx9pzhj 2739 20 dynamics dynamic NNS cord-005646-xhx9pzhj 2739 21 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2739 22 on on IN cord-005646-xhx9pzhj 2739 23 radiological radiological JJ cord-005646-xhx9pzhj 2739 24 screening screening NN cord-005646-xhx9pzhj 2739 25 . . . cord-005646-xhx9pzhj 2740 1 Case case NN cord-005646-xhx9pzhj 2740 2 Descriptions description NNS cord-005646-xhx9pzhj 2740 3 : : : cord-005646-xhx9pzhj 2741 1 Three three CD cord-005646-xhx9pzhj 2741 2 infants infant NNS cord-005646-xhx9pzhj 2741 3 who who WP cord-005646-xhx9pzhj 2741 4 were be VBD cord-005646-xhx9pzhj 2741 5 difficult difficult JJ cord-005646-xhx9pzhj 2741 6 to to TO cord-005646-xhx9pzhj 2741 7 ventilate ventilate VB cord-005646-xhx9pzhj 2741 8 requiring require VBG cord-005646-xhx9pzhj 2741 9 high high JJ cord-005646-xhx9pzhj 2741 10 airway airway NN cord-005646-xhx9pzhj 2741 11 pressures pressure NNS cord-005646-xhx9pzhj 2741 12 , , , cord-005646-xhx9pzhj 2741 13 high high JJ cord-005646-xhx9pzhj 2741 14 PEEP peep NN cord-005646-xhx9pzhj 2741 15 and and CC cord-005646-xhx9pzhj 2741 16 a a DT cord-005646-xhx9pzhj 2741 17 significant significant JJ cord-005646-xhx9pzhj 2741 18 oxygen oxygen NN cord-005646-xhx9pzhj 2741 19 requirement requirement NN cord-005646-xhx9pzhj 2741 20 had have VBD cord-005646-xhx9pzhj 2741 21 TBGs tbg NNS cord-005646-xhx9pzhj 2741 22 . . . cord-005646-xhx9pzhj 2742 1 The the DT cord-005646-xhx9pzhj 2742 2 ages age NNS cord-005646-xhx9pzhj 2742 3 ranged range VBD cord-005646-xhx9pzhj 2742 4 from from IN cord-005646-xhx9pzhj 2742 5 3 3 CD cord-005646-xhx9pzhj 2742 6 to to TO cord-005646-xhx9pzhj 2742 7 9 9 CD cord-005646-xhx9pzhj 2742 8 months month NNS cord-005646-xhx9pzhj 2742 9 . . . cord-005646-xhx9pzhj 2743 1 Two two CD cord-005646-xhx9pzhj 2743 2 cases case NNS cord-005646-xhx9pzhj 2743 3 were be VBD cord-005646-xhx9pzhj 2743 4 complicated complicate VBN cord-005646-xhx9pzhj 2743 5 by by IN cord-005646-xhx9pzhj 2743 6 complex complex JJ cord-005646-xhx9pzhj 2743 7 cardiac cardiac JJ cord-005646-xhx9pzhj 2743 8 lesions lesion NNS cord-005646-xhx9pzhj 2743 9 . . . cord-005646-xhx9pzhj 2744 1 In in IN cord-005646-xhx9pzhj 2744 2 all all DT cord-005646-xhx9pzhj 2744 3 cases case NNS cord-005646-xhx9pzhj 2744 4 there there EX cord-005646-xhx9pzhj 2744 5 were be VBD cord-005646-xhx9pzhj 2744 6 frequent frequent JJ cord-005646-xhx9pzhj 2744 7 episodes episode NNS cord-005646-xhx9pzhj 2744 8 of of IN cord-005646-xhx9pzhj 2744 9 desaturation desaturation NN cord-005646-xhx9pzhj 2744 10 , , , cord-005646-xhx9pzhj 2744 11 where where WRB cord-005646-xhx9pzhj 2744 12 hand hand NN cord-005646-xhx9pzhj 2744 13 ventilation ventilation NN cord-005646-xhx9pzhj 2744 14 proved prove VBD cord-005646-xhx9pzhj 2744 15 difficult difficult JJ cord-005646-xhx9pzhj 2744 16 and and CC cord-005646-xhx9pzhj 2744 17 various various JJ cord-005646-xhx9pzhj 2744 18 intermittent intermittent JJ cord-005646-xhx9pzhj 2744 19 lobar lobar NN cord-005646-xhx9pzhj 2744 20 collapses collapse NNS cord-005646-xhx9pzhj 2744 21 occurred occur VBD cord-005646-xhx9pzhj 2744 22 . . . cord-005646-xhx9pzhj 2745 1 Microlaryngobronchoscopies Microlaryngobronchoscopies NNP cord-005646-xhx9pzhj 2745 2 ( ( -LRB- cord-005646-xhx9pzhj 2745 3 MLB MLB NNP cord-005646-xhx9pzhj 2745 4 ) ) -RRB- cord-005646-xhx9pzhj 2745 5 performed perform VBN cord-005646-xhx9pzhj 2745 6 on on IN cord-005646-xhx9pzhj 2745 7 the the DT cord-005646-xhx9pzhj 2745 8 infants infant NNS cord-005646-xhx9pzhj 2745 9 by by IN cord-005646-xhx9pzhj 2745 10 experienced experienced JJ cord-005646-xhx9pzhj 2745 11 paediatric paediatric JJ cord-005646-xhx9pzhj 2745 12 ENT ENT NNP cord-005646-xhx9pzhj 2745 13 surgeons surgeon NNS cord-005646-xhx9pzhj 2745 14 failed fail VBD cord-005646-xhx9pzhj 2745 15 to to TO cord-005646-xhx9pzhj 2745 16 identify identify VB cord-005646-xhx9pzhj 2745 17 the the DT cord-005646-xhx9pzhj 2745 18 airway airway NN cord-005646-xhx9pzhj 2745 19 problems problem NNS cord-005646-xhx9pzhj 2745 20 . . . cord-005646-xhx9pzhj 2746 1 More More JJR cord-005646-xhx9pzhj 2746 2 than than IN cord-005646-xhx9pzhj 2746 3 one one CD cord-005646-xhx9pzhj 2746 4 MLB MLB NNP cord-005646-xhx9pzhj 2746 5 was be VBD cord-005646-xhx9pzhj 2746 6 frequently frequently RB cord-005646-xhx9pzhj 2746 7 done do VBN cord-005646-xhx9pzhj 2746 8 . . . cord-005646-xhx9pzhj 2747 1 Concern concern NN cord-005646-xhx9pzhj 2747 2 about about IN cord-005646-xhx9pzhj 2747 3 introducing introduce VBG cord-005646-xhx9pzhj 2747 4 contrast contrast NN cord-005646-xhx9pzhj 2747 5 into into IN cord-005646-xhx9pzhj 2747 6 the the DT cord-005646-xhx9pzhj 2747 7 airways airway NNS cord-005646-xhx9pzhj 2747 8 of of IN cord-005646-xhx9pzhj 2747 9 infants infant NNS cord-005646-xhx9pzhj 2747 10 with with IN cord-005646-xhx9pzhj 2747 11 limited limited JJ cord-005646-xhx9pzhj 2747 12 cardiorespiratory cardiorespiratory JJ cord-005646-xhx9pzhj 2747 13 reserve reserve NN cord-005646-xhx9pzhj 2747 14 combined combine VBN cord-005646-xhx9pzhj 2747 15 with with IN cord-005646-xhx9pzhj 2747 16 an an DT cord-005646-xhx9pzhj 2747 17 uncertainty uncertainty NN cord-005646-xhx9pzhj 2747 18 about about IN cord-005646-xhx9pzhj 2747 19 how how WRB cord-005646-xhx9pzhj 2747 20 much much JJ cord-005646-xhx9pzhj 2747 21 extra extra JJ cord-005646-xhx9pzhj 2747 22 intbrmafion intbrmafion NN cord-005646-xhx9pzhj 2747 23 would would MD cord-005646-xhx9pzhj 2747 24 be be VB cord-005646-xhx9pzhj 2747 25 gained gain VBN cord-005646-xhx9pzhj 2747 26 often often RB cord-005646-xhx9pzhj 2747 27 led lead VBN cord-005646-xhx9pzhj 2747 28 to to IN cord-005646-xhx9pzhj 2747 29 a a DT cord-005646-xhx9pzhj 2747 30 delay delay NN cord-005646-xhx9pzhj 2747 31 in in IN cord-005646-xhx9pzhj 2747 32 investigation investigation NN cord-005646-xhx9pzhj 2747 33 . . . cord-005646-xhx9pzhj 2748 1 When when WRB cord-005646-xhx9pzhj 2748 2 performed perform VBN cord-005646-xhx9pzhj 2748 3 these these DT cord-005646-xhx9pzhj 2748 4 fears fear NNS cord-005646-xhx9pzhj 2748 5 proved prove VBD cord-005646-xhx9pzhj 2748 6 groundless groundless JJ cord-005646-xhx9pzhj 2748 7 , , , cord-005646-xhx9pzhj 2748 8 the the DT cord-005646-xhx9pzhj 2748 9 anatomy anatomy NN cord-005646-xhx9pzhj 2748 10 and and CC cord-005646-xhx9pzhj 2748 11 pathology pathology NN cord-005646-xhx9pzhj 2748 12 of of IN cord-005646-xhx9pzhj 2748 13 the the DT cord-005646-xhx9pzhj 2748 14 airways airways NNPS cord-005646-xhx9pzhj 2748 15 were be VBD cord-005646-xhx9pzhj 2748 16 demonstrated demonstrate VBN cord-005646-xhx9pzhj 2748 17 in in IN cord-005646-xhx9pzhj 2748 18 full full JJ cord-005646-xhx9pzhj 2748 19 and and CC cord-005646-xhx9pzhj 2748 20 the the DT cord-005646-xhx9pzhj 2748 21 correct correct JJ cord-005646-xhx9pzhj 2748 22 therapeutic therapeutic JJ cord-005646-xhx9pzhj 2748 23 plan plan NN cord-005646-xhx9pzhj 2748 24 started start VBD cord-005646-xhx9pzhj 2748 25 . . . cord-005646-xhx9pzhj 2749 1 In in IN cord-005646-xhx9pzhj 2749 2 two two CD cord-005646-xhx9pzhj 2749 3 cases case NNS cord-005646-xhx9pzhj 2749 4 tracheostomy tracheostomy NN cord-005646-xhx9pzhj 2749 5 and and CC cord-005646-xhx9pzhj 2749 6 PEEP peep NN cord-005646-xhx9pzhj 2749 7 producing produce VBG cord-005646-xhx9pzhj 2749 8 patency patency NN cord-005646-xhx9pzhj 2749 9 of of IN cord-005646-xhx9pzhj 2749 10 bronchomalacic bronchomalacic NN cord-005646-xhx9pzhj 2749 11 segments segment NNS cord-005646-xhx9pzhj 2749 12 allowed allow VBD cord-005646-xhx9pzhj 2749 13 weaning wean VBG cord-005646-xhx9pzhj 2749 14 to to IN cord-005646-xhx9pzhj 2749 15 low low JJ cord-005646-xhx9pzhj 2749 16 levels level NNS cord-005646-xhx9pzhj 2749 17 of of IN cord-005646-xhx9pzhj 2749 18 ventitatory ventitatory NN cord-005646-xhx9pzhj 2749 19 support support NN cord-005646-xhx9pzhj 2749 20 . . . cord-005646-xhx9pzhj 2750 1 In in IN cord-005646-xhx9pzhj 2750 2 one one CD cord-005646-xhx9pzhj 2750 3 case case NN cord-005646-xhx9pzhj 2750 4 tracheal tracheal JJ cord-005646-xhx9pzhj 2750 5 reconstruction reconstruction NN cord-005646-xhx9pzhj 2750 6 was be VBD cord-005646-xhx9pzhj 2750 7 undertaken undertake VBN cord-005646-xhx9pzhj 2750 8 and and CC cord-005646-xhx9pzhj 2750 9 in in IN cord-005646-xhx9pzhj 2750 10 the the DT cord-005646-xhx9pzhj 2750 11 cardiac cardiac NN cord-005646-xhx9pzhj 2750 12 cases case NNS cord-005646-xhx9pzhj 2750 13 the the DT cord-005646-xhx9pzhj 2750 14 respiratory respiratory JJ cord-005646-xhx9pzhj 2750 15 component component NN cord-005646-xhx9pzhj 2750 16 of of IN cord-005646-xhx9pzhj 2750 17 the the DT cord-005646-xhx9pzhj 2750 18 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2750 19 dependence dependence NN cord-005646-xhx9pzhj 2750 20 was be VBD cord-005646-xhx9pzhj 2750 21 fully fully RB cord-005646-xhx9pzhj 2750 22 assessed assess VBN cord-005646-xhx9pzhj 2750 23 . . . cord-005646-xhx9pzhj 2751 1 At at IN cord-005646-xhx9pzhj 2751 2 the the DT cord-005646-xhx9pzhj 2751 3 age age NN cord-005646-xhx9pzhj 2751 4 of of IN cord-005646-xhx9pzhj 2751 5 4 4 CD cord-005646-xhx9pzhj 2751 6 months month NNS cord-005646-xhx9pzhj 2751 7 , , , cord-005646-xhx9pzhj 2751 8 a a DT cord-005646-xhx9pzhj 2751 9 baby baby NN cord-005646-xhx9pzhj 2751 10 boy boy NN cord-005646-xhx9pzhj 2751 11 with with IN cord-005646-xhx9pzhj 2751 12 a a DT cord-005646-xhx9pzhj 2751 13 history history NN cord-005646-xhx9pzhj 2751 14 of of IN cord-005646-xhx9pzhj 2751 15 minor minor JJ cord-005646-xhx9pzhj 2751 16 respiratory respiratory JJ cord-005646-xhx9pzhj 2751 17 problems problem NNS cord-005646-xhx9pzhj 2751 18 , , , cord-005646-xhx9pzhj 2751 19 was be VBD cord-005646-xhx9pzhj 2751 20 admitted admit VBN cord-005646-xhx9pzhj 2751 21 to to IN cord-005646-xhx9pzhj 2751 22 hospital hospital NN cord-005646-xhx9pzhj 2751 23 with with IN cord-005646-xhx9pzhj 2751 24 an an DT cord-005646-xhx9pzhj 2751 25 upper upper JJ cord-005646-xhx9pzhj 2751 26 airway airway NN cord-005646-xhx9pzhj 2751 27 infection infection NN cord-005646-xhx9pzhj 2751 28 and and CC cord-005646-xhx9pzhj 2751 29 severe severe JJ cord-005646-xhx9pzhj 2751 30 dyspnoea dyspnoea NNS cord-005646-xhx9pzhj 2751 31 . . . cord-005646-xhx9pzhj 2752 1 Shortly shortly RB cord-005646-xhx9pzhj 2752 2 after after IN cord-005646-xhx9pzhj 2752 3 arrival arrival NN cord-005646-xhx9pzhj 2752 4 at at IN cord-005646-xhx9pzhj 2752 5 the the DT cord-005646-xhx9pzhj 2752 6 ICU ICU NNP cord-005646-xhx9pzhj 2752 7 he -PRON- PRP cord-005646-xhx9pzhj 2752 8 had have VBD cord-005646-xhx9pzhj 2752 9 a a DT cord-005646-xhx9pzhj 2752 10 total total JJ cord-005646-xhx9pzhj 2752 11 airway airway NN cord-005646-xhx9pzhj 2752 12 obstruction obstruction NN cord-005646-xhx9pzhj 2752 13 . . . cord-005646-xhx9pzhj 2753 1 After after IN cord-005646-xhx9pzhj 2753 2 intubation intubation NN cord-005646-xhx9pzhj 2753 3 there there EX cord-005646-xhx9pzhj 2753 4 were be VBD cord-005646-xhx9pzhj 2753 5 still still RB cord-005646-xhx9pzhj 2753 6 difficulties difficulty NNS cord-005646-xhx9pzhj 2753 7 to to TO cord-005646-xhx9pzhj 2753 8 establish establish VB cord-005646-xhx9pzhj 2753 9 a a DT cord-005646-xhx9pzhj 2753 10 normal normal JJ cord-005646-xhx9pzhj 2753 11 gas gas NN cord-005646-xhx9pzhj 2753 12 exchange exchange NN cord-005646-xhx9pzhj 2753 13 , , , cord-005646-xhx9pzhj 2753 14 and and CC cord-005646-xhx9pzhj 2753 15 he -PRON- PRP cord-005646-xhx9pzhj 2753 16 was be VBD cord-005646-xhx9pzhj 2753 17 tranferred tranferre VBN cord-005646-xhx9pzhj 2753 18 to to IN cord-005646-xhx9pzhj 2753 19 the the DT cord-005646-xhx9pzhj 2753 20 regional regional JJ cord-005646-xhx9pzhj 2753 21 PICU PICU NNP cord-005646-xhx9pzhj 2753 22 . . . cord-005646-xhx9pzhj 2754 1 CT CT NNP cord-005646-xhx9pzhj 2754 2 scan scan NN cord-005646-xhx9pzhj 2754 3 and and CC cord-005646-xhx9pzhj 2754 4 bronchoscopy bronchoscopy NN cord-005646-xhx9pzhj 2754 5 verified verify VBD cord-005646-xhx9pzhj 2754 6 a a DT cord-005646-xhx9pzhj 2754 7 congenital congenital JJ cord-005646-xhx9pzhj 2754 8 tracheal tracheal NN cord-005646-xhx9pzhj 2754 9 stenosis stenosis NN cord-005646-xhx9pzhj 2754 10 affecting affect VBG cord-005646-xhx9pzhj 2754 11 the the DT cord-005646-xhx9pzhj 2754 12 whole whole JJ cord-005646-xhx9pzhj 2754 13 trachea trachea NN cord-005646-xhx9pzhj 2754 14 except except IN cord-005646-xhx9pzhj 2754 15 the the DT cord-005646-xhx9pzhj 2754 16 upper upper JJ cord-005646-xhx9pzhj 2754 17 15 15 CD cord-005646-xhx9pzhj 2754 18 mm mm NN cord-005646-xhx9pzhj 2754 19 below below IN cord-005646-xhx9pzhj 2754 20 the the DT cord-005646-xhx9pzhj 2754 21 vocal vocal JJ cord-005646-xhx9pzhj 2754 22 cords cord NNS cord-005646-xhx9pzhj 2754 23 . . . cord-005646-xhx9pzhj 2755 1 The the DT cord-005646-xhx9pzhj 2755 2 diameter diameter NN cord-005646-xhx9pzhj 2755 3 was be VBD cord-005646-xhx9pzhj 2755 4 estimated estimate VBN cord-005646-xhx9pzhj 2755 5 to to IN cord-005646-xhx9pzhj 2755 6 less less JJR cord-005646-xhx9pzhj 2755 7 than than IN cord-005646-xhx9pzhj 2755 8 2 2 CD cord-005646-xhx9pzhj 2755 9 ram ram NN cord-005646-xhx9pzhj 2755 10 . . . cord-005646-xhx9pzhj 2756 1 An an DT cord-005646-xhx9pzhj 2756 2 unsuccessful unsuccessful JJ cord-005646-xhx9pzhj 2756 3 attempt attempt NN cord-005646-xhx9pzhj 2756 4 was be VBD cord-005646-xhx9pzhj 2756 5 made make VBN cord-005646-xhx9pzhj 2756 6 to to TO cord-005646-xhx9pzhj 2756 7 dilate dilate VB cord-005646-xhx9pzhj 2756 8 the the DT cord-005646-xhx9pzhj 2756 9 extremely extremely RB cord-005646-xhx9pzhj 2756 10 rigid rigid JJ cord-005646-xhx9pzhj 2756 11 stenosis stenosis NN cord-005646-xhx9pzhj 2756 12 with with IN cord-005646-xhx9pzhj 2756 13 a a DT cord-005646-xhx9pzhj 2756 14 balloon balloon NN cord-005646-xhx9pzhj 2756 15 . . . cord-005646-xhx9pzhj 2757 1 After after IN cord-005646-xhx9pzhj 2757 2 the the DT cord-005646-xhx9pzhj 2757 3 procedure procedure NN cord-005646-xhx9pzhj 2757 4 he -PRON- PRP cord-005646-xhx9pzhj 2757 5 had have VBD cord-005646-xhx9pzhj 2757 6 a a DT cord-005646-xhx9pzhj 2757 7 respiratory respiratory JJ cord-005646-xhx9pzhj 2757 8 and and CC cord-005646-xhx9pzhj 2757 9 circulatory circulatory JJ cord-005646-xhx9pzhj 2757 10 arrest arrest NN cord-005646-xhx9pzhj 2757 11 , , , cord-005646-xhx9pzhj 2757 12 and and CC cord-005646-xhx9pzhj 2757 13 he -PRON- PRP cord-005646-xhx9pzhj 2757 14 was be VBD cord-005646-xhx9pzhj 2757 15 put put VBN cord-005646-xhx9pzhj 2757 16 on on IN cord-005646-xhx9pzhj 2757 17 ECMO ECMO NNP cord-005646-xhx9pzhj 2757 18 as as IN cord-005646-xhx9pzhj 2757 19 a a DT cord-005646-xhx9pzhj 2757 20 bridge bridge NN cord-005646-xhx9pzhj 2757 21 to to IN cord-005646-xhx9pzhj 2757 22 surgical surgical JJ cord-005646-xhx9pzhj 2757 23 correction correction NN cord-005646-xhx9pzhj 2757 24 . . . cord-005646-xhx9pzhj 2758 1 After after IN cord-005646-xhx9pzhj 2758 2 4 4 CD cord-005646-xhx9pzhj 2758 3 stable stable JJ cord-005646-xhx9pzhj 2758 4 days day NNS cord-005646-xhx9pzhj 2758 5 on on IN cord-005646-xhx9pzhj 2758 6 ECMO ECMO NNP cord-005646-xhx9pzhj 2758 7 , , , cord-005646-xhx9pzhj 2758 8 surgery surgery NN cord-005646-xhx9pzhj 2758 9 was be VBD cord-005646-xhx9pzhj 2758 10 performed perform VBN cord-005646-xhx9pzhj 2758 11 during during IN cord-005646-xhx9pzhj 2758 12 ECMO ECMO NNP cord-005646-xhx9pzhj 2758 13 with with IN cord-005646-xhx9pzhj 2758 14 a a DT cord-005646-xhx9pzhj 2758 15 tracheal tracheal JJ cord-005646-xhx9pzhj 2758 16 homograft homograft NN cord-005646-xhx9pzhj 2758 17 transplantation transplantation NN cord-005646-xhx9pzhj 2758 18 . . . cord-005646-xhx9pzhj 2759 1 Immediately immediately RB cord-005646-xhx9pzhj 2759 2 after after IN cord-005646-xhx9pzhj 2759 3 surgery surgery NN cord-005646-xhx9pzhj 2759 4 , , , cord-005646-xhx9pzhj 2759 5 ECMO ECMO NNP cord-005646-xhx9pzhj 2759 6 was be VBD cord-005646-xhx9pzhj 2759 7 discontinued discontinue VBN cord-005646-xhx9pzhj 2759 8 . . . cord-005646-xhx9pzhj 2760 1 A a DT cord-005646-xhx9pzhj 2760 2 silastic silastic JJ cord-005646-xhx9pzhj 2760 3 Dumont Dumont NNP cord-005646-xhx9pzhj 2760 4 type type NN cord-005646-xhx9pzhj 2760 5 stcnt stcnt NNP cord-005646-xhx9pzhj 2760 6 was be VBD cord-005646-xhx9pzhj 2760 7 inserted insert VBN cord-005646-xhx9pzhj 2760 8 inside inside IN cord-005646-xhx9pzhj 2760 9 the the DT cord-005646-xhx9pzhj 2760 10 homogra~ homogra~ NNP cord-005646-xhx9pzhj 2760 11 , , , cord-005646-xhx9pzhj 2760 12 and and CC cord-005646-xhx9pzhj 2760 13 a a DT cord-005646-xhx9pzhj 2760 14 nasotracheal nasotracheal JJ cord-005646-xhx9pzhj 2760 15 tube tube NN cord-005646-xhx9pzhj 2760 16 was be VBD cord-005646-xhx9pzhj 2760 17 placed place VBN cord-005646-xhx9pzhj 2760 18 inside inside IN cord-005646-xhx9pzhj 2760 19 the the DT cord-005646-xhx9pzhj 2760 20 stent stent NN cord-005646-xhx9pzhj 2760 21 for for IN cord-005646-xhx9pzhj 2760 22 assisted assist VBN cord-005646-xhx9pzhj 2760 23 intermittent intermittent JJ cord-005646-xhx9pzhj 2760 24 mechanical mechanical JJ cord-005646-xhx9pzhj 2760 25 ventilation ventilation NN cord-005646-xhx9pzhj 2760 26 . . . cord-005646-xhx9pzhj 2761 1 Repeated repeat VBN cord-005646-xhx9pzhj 2761 2 bronchoscopies bronchoscopie NNS cord-005646-xhx9pzhj 2761 3 were be VBD cord-005646-xhx9pzhj 2761 4 performed perform VBN cord-005646-xhx9pzhj 2761 5 to to TO cord-005646-xhx9pzhj 2761 6 remove remove VB cord-005646-xhx9pzhj 2761 7 granulation granulation NN cord-005646-xhx9pzhj 2761 8 tissue tissue NN cord-005646-xhx9pzhj 2761 9 and and CC cord-005646-xhx9pzhj 2761 10 secretions secretion NNS cord-005646-xhx9pzhj 2761 11 . . . cord-005646-xhx9pzhj 2762 1 At at IN cord-005646-xhx9pzhj 2762 2 9 9 CD cord-005646-xhx9pzhj 2762 3 months month NNS cord-005646-xhx9pzhj 2762 4 of of IN cord-005646-xhx9pzhj 2762 5 age age NN cord-005646-xhx9pzhj 2762 6 , , , cord-005646-xhx9pzhj 2762 7 the the DT cord-005646-xhx9pzhj 2762 8 stem stem NN cord-005646-xhx9pzhj 2762 9 was be VBD cord-005646-xhx9pzhj 2762 10 removed remove VBN cord-005646-xhx9pzhj 2762 11 with with IN cord-005646-xhx9pzhj 2762 12 an an DT cord-005646-xhx9pzhj 2762 13 endoscopic endoscopic JJ cord-005646-xhx9pzhj 2762 14 procedure procedure NN cord-005646-xhx9pzhj 2762 15 . . . cord-005646-xhx9pzhj 2763 1 However however RB cord-005646-xhx9pzhj 2763 2 , , , cord-005646-xhx9pzhj 2763 3 the the DT cord-005646-xhx9pzhj 2763 4 trachea trachea NN cord-005646-xhx9pzhj 2763 5 was be VBD cord-005646-xhx9pzhj 2763 6 still still RB cord-005646-xhx9pzhj 2763 7 soft soft JJ cord-005646-xhx9pzhj 2763 8 and and CC cord-005646-xhx9pzhj 2763 9 collapsable collapsable JJ cord-005646-xhx9pzhj 2763 10 , , , cord-005646-xhx9pzhj 2763 11 and and CC cord-005646-xhx9pzhj 2763 12 another another DT cord-005646-xhx9pzhj 2763 13 silicon silicon NN cord-005646-xhx9pzhj 2763 14 stent stent NN cord-005646-xhx9pzhj 2763 15 was be VBD cord-005646-xhx9pzhj 2763 16 placed place VBN cord-005646-xhx9pzhj 2763 17 inside inside IN cord-005646-xhx9pzhj 2763 18 the the DT cord-005646-xhx9pzhj 2763 19 trachea trachea NN cord-005646-xhx9pzhj 2763 20 for for IN cord-005646-xhx9pzhj 2763 21 another another DT cord-005646-xhx9pzhj 2763 22 4 4 CD cord-005646-xhx9pzhj 2763 23 months month NNS cord-005646-xhx9pzhj 2763 24 period period NN cord-005646-xhx9pzhj 2763 25 , , , cord-005646-xhx9pzhj 2763 26 After after IN cord-005646-xhx9pzhj 2763 27 removal removal NN cord-005646-xhx9pzhj 2763 28 he -PRON- PRP cord-005646-xhx9pzhj 2763 29 had have VBD cord-005646-xhx9pzhj 2763 30 some some DT cord-005646-xhx9pzhj 2763 31 respiratory respiratory JJ cord-005646-xhx9pzhj 2763 32 problems problem NNS cord-005646-xhx9pzhj 2763 33 and and CC cord-005646-xhx9pzhj 2763 34 he -PRON- PRP cord-005646-xhx9pzhj 2763 35 was be VBD cord-005646-xhx9pzhj 2763 36 treated treat VBN cord-005646-xhx9pzhj 2763 37 with with IN cord-005646-xhx9pzhj 2763 38 nebulized nebulize VBN cord-005646-xhx9pzhj 2763 39 salbutamol salbutamol NN cord-005646-xhx9pzhj 2763 40 , , , cord-005646-xhx9pzhj 2763 41 mcemic mcemic JJ cord-005646-xhx9pzhj 2763 42 epinephrine epinephrine NN cord-005646-xhx9pzhj 2763 43 and and CC cord-005646-xhx9pzhj 2763 44 steroids steroid NNS cord-005646-xhx9pzhj 2763 45 . . . cord-005646-xhx9pzhj 2764 1 He -PRON- PRP cord-005646-xhx9pzhj 2764 2 was be VBD cord-005646-xhx9pzhj 2764 3 discharged discharge VBN cord-005646-xhx9pzhj 2764 4 from from IN cord-005646-xhx9pzhj 2764 5 the the DT cord-005646-xhx9pzhj 2764 6 hospital hospital NN cord-005646-xhx9pzhj 2764 7 at at IN cord-005646-xhx9pzhj 2764 8 14 14 CD cord-005646-xhx9pzhj 2764 9 months month NNS cord-005646-xhx9pzhj 2764 10 of of IN cord-005646-xhx9pzhj 2764 11 age age NN cord-005646-xhx9pzhj 2764 12 and and CC cord-005646-xhx9pzhj 2764 13 his -PRON- PRP$ cord-005646-xhx9pzhj 2764 14 condition condition NN cord-005646-xhx9pzhj 2764 15 is be VBZ cord-005646-xhx9pzhj 2764 16 now now RB cord-005646-xhx9pzhj 2764 17 stable stable JJ cord-005646-xhx9pzhj 2764 18 . . . cord-005646-xhx9pzhj 2765 1 This this DT cord-005646-xhx9pzhj 2765 2 is be VBZ cord-005646-xhx9pzhj 2765 3 the the DT cord-005646-xhx9pzhj 2765 4 first first JJ cord-005646-xhx9pzhj 2765 5 procedure procedure NN cord-005646-xhx9pzhj 2765 6 of of IN cord-005646-xhx9pzhj 2765 7 its -PRON- PRP$ cord-005646-xhx9pzhj 2765 8 kind kind NN cord-005646-xhx9pzhj 2765 9 in in IN cord-005646-xhx9pzhj 2765 10 Sweden Sweden NNP cord-005646-xhx9pzhj 2765 11 . . . cord-005646-xhx9pzhj 2766 1 It -PRON- PRP cord-005646-xhx9pzhj 2766 2 was be VBD cord-005646-xhx9pzhj 2766 3 accomplished accomplish VBN cord-005646-xhx9pzhj 2766 4 by by IN cord-005646-xhx9pzhj 2766 5 international international JJ cord-005646-xhx9pzhj 2766 6 and and CC cord-005646-xhx9pzhj 2766 7 multidisciplinary multidisciplinary JJ cord-005646-xhx9pzhj 2766 8 collaboration collaboration NN cord-005646-xhx9pzhj 2766 9 . . . cord-005646-xhx9pzhj 2767 1 ECMO ECMO NNP cord-005646-xhx9pzhj 2767 2 may may MD cord-005646-xhx9pzhj 2767 3 be be VB cord-005646-xhx9pzhj 2767 4 a a DT cord-005646-xhx9pzhj 2767 5 bridge bridge NN cord-005646-xhx9pzhj 2767 6 to to IN cord-005646-xhx9pzhj 2767 7 corrective corrective JJ cord-005646-xhx9pzhj 2767 8 surgery surgery NN cord-005646-xhx9pzhj 2767 9 and and CC cord-005646-xhx9pzhj 2767 10 long long JJ cord-005646-xhx9pzhj 2767 11 time time NN cord-005646-xhx9pzhj 2767 12 stenting stente VBG cord-005646-xhx9pzhj 2767 13 may may MD cord-005646-xhx9pzhj 2767 14 be be VB cord-005646-xhx9pzhj 2767 15 necessary necessary JJ cord-005646-xhx9pzhj 2767 16 in in IN cord-005646-xhx9pzhj 2767 17 the the DT cord-005646-xhx9pzhj 2767 18 postoperative postoperative JJ cord-005646-xhx9pzhj 2767 19 period period NN cord-005646-xhx9pzhj 2767 20 . . . cord-005646-xhx9pzhj 2768 1 Post post JJ cord-005646-xhx9pzhj 2768 2 mtubation mtubation NN cord-005646-xhx9pzhj 2768 3 Laryngitis Laryngitis NNP cord-005646-xhx9pzhj 2768 4 ( ( -LRB- cord-005646-xhx9pzhj 2768 5 PIL PIL NNP cord-005646-xhx9pzhj 2768 6 ) ) -RRB- cord-005646-xhx9pzhj 2768 7 is be VBZ cord-005646-xhx9pzhj 2768 8 still still RB cord-005646-xhx9pzhj 2768 9 a a DT cord-005646-xhx9pzhj 2768 10 frequent frequent JJ cord-005646-xhx9pzhj 2768 11 complication complication NN cord-005646-xhx9pzhj 2768 12 , , , cord-005646-xhx9pzhj 2768 13 occurmg occurmg NNP cord-005646-xhx9pzhj 2768 14 in in IN cord-005646-xhx9pzhj 2768 15 l l NNP cord-005646-xhx9pzhj 2768 16 -6 -6 NNP cord-005646-xhx9pzhj 2768 17 % % NN cord-005646-xhx9pzhj 2768 18 of of IN cord-005646-xhx9pzhj 2768 19 intubated intubate VBN cord-005646-xhx9pzhj 2768 20 patients patient NNS cord-005646-xhx9pzhj 2768 21 . . . cord-005646-xhx9pzhj 2769 1 Inhaled inhale VBN cord-005646-xhx9pzhj 2769 2 racemic racemic JJ cord-005646-xhx9pzhj 2769 3 epinephrine epinephrine NN cord-005646-xhx9pzhj 2769 4 has have VBZ cord-005646-xhx9pzhj 2769 5 for for IN cord-005646-xhx9pzhj 2769 6 long long RB cord-005646-xhx9pzhj 2769 7 been be VBN cord-005646-xhx9pzhj 2769 8 used use VBN cord-005646-xhx9pzhj 2769 9 as as IN cord-005646-xhx9pzhj 2769 10 an an DT cord-005646-xhx9pzhj 2769 11 accepted accept VBN cord-005646-xhx9pzhj 2769 12 therapy therapy NN cord-005646-xhx9pzhj 2769 13 , , , cord-005646-xhx9pzhj 2769 14 but but CC cord-005646-xhx9pzhj 2769 15 this this DT cord-005646-xhx9pzhj 2769 16 drug drug NN cord-005646-xhx9pzhj 2769 17 is be VBZ cord-005646-xhx9pzhj 2769 18 not not RB cord-005646-xhx9pzhj 2769 19 always always RB cord-005646-xhx9pzhj 2769 20 available available JJ cord-005646-xhx9pzhj 2769 21 . . . cord-005646-xhx9pzhj 2770 1 The the DT cord-005646-xhx9pzhj 2770 2 authors author NNS cord-005646-xhx9pzhj 2770 3 undertook undertake VBD cord-005646-xhx9pzhj 2770 4 a a DT cord-005646-xhx9pzhj 2770 5 randomized randomized JJ cord-005646-xhx9pzhj 2770 6 , , , cord-005646-xhx9pzhj 2770 7 double double JJ cord-005646-xhx9pzhj 2770 8 - - HYPH cord-005646-xhx9pzhj 2770 9 blind blind JJ cord-005646-xhx9pzhj 2770 10 , , , cord-005646-xhx9pzhj 2770 11 placebo placebo NN cord-005646-xhx9pzhj 2770 12 - - HYPH cord-005646-xhx9pzhj 2770 13 controlled control VBN cord-005646-xhx9pzhj 2770 14 trial trial NN cord-005646-xhx9pzhj 2770 15 to to TO cord-005646-xhx9pzhj 2770 16 determine determine VB cord-005646-xhx9pzhj 2770 17 the the DT cord-005646-xhx9pzhj 2770 18 efficacy efficacy NN cord-005646-xhx9pzhj 2770 19 of of IN cord-005646-xhx9pzhj 2770 20 inhaled inhale VBN cord-005646-xhx9pzhj 2770 21 L l NN cord-005646-xhx9pzhj 2770 22 - - HYPH cord-005646-xhx9pzhj 2770 23 epinephrine(LE epinephrine(LE NNP cord-005646-xhx9pzhj 2770 24 ) ) -RRB- cord-005646-xhx9pzhj 2771 1 in in IN cord-005646-xhx9pzhj 2771 2 the the DT cord-005646-xhx9pzhj 2771 3 treatment treatment NN cord-005646-xhx9pzhj 2771 4 of of IN cord-005646-xhx9pzhj 2771 5 PlU plu NN cord-005646-xhx9pzhj 2772 1 In in IN cord-005646-xhx9pzhj 2772 2 the the DT cord-005646-xhx9pzhj 2772 3 period period NN cord-005646-xhx9pzhj 2772 4 between between IN cord-005646-xhx9pzhj 2772 5 july/93 july/93 NNP cord-005646-xhx9pzhj 2772 6 and and CC cord-005646-xhx9pzhj 2772 7 may/95 may/95 NNP cord-005646-xhx9pzhj 2772 8 , , , cord-005646-xhx9pzhj 2772 9 289 289 CD cord-005646-xhx9pzhj 2772 10 patients patient NNS cord-005646-xhx9pzhj 2772 11 were be VBD cord-005646-xhx9pzhj 2772 12 submitted submit VBN cord-005646-xhx9pzhj 2772 13 to to TO cord-005646-xhx9pzhj 2772 14 endotracheal endotracheal VB cord-005646-xhx9pzhj 2772 15 intubation intubation NN cord-005646-xhx9pzhj 2772 16 for for IN cord-005646-xhx9pzhj 2772 17 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2772 18 support support NN cord-005646-xhx9pzhj 2772 19 . . . cord-005646-xhx9pzhj 2773 1 Atter Atter NNP cord-005646-xhx9pzhj 2773 2 the the DT cord-005646-xhx9pzhj 2773 3 extubation extubation NN cord-005646-xhx9pzhj 2773 4 procedure procedure NN cord-005646-xhx9pzhj 2773 5 patients patient NNS cord-005646-xhx9pzhj 2773 6 were be VBD cord-005646-xhx9pzhj 2773 7 considered consider VBN cord-005646-xhx9pzhj 2773 8 for for IN cord-005646-xhx9pzhj 2773 9 enrollement enrollement NN cord-005646-xhx9pzhj 2773 10 if if IN cord-005646-xhx9pzhj 2773 11 they -PRON- PRP cord-005646-xhx9pzhj 2773 12 met meet VBD cord-005646-xhx9pzhj 2773 13 the the DT cord-005646-xhx9pzhj 2773 14 following follow VBG cord-005646-xhx9pzhj 2773 15 criteria criterion NNS cord-005646-xhx9pzhj 2773 16 : : : cord-005646-xhx9pzhj 2774 1 clinical clinical JJ cord-005646-xhx9pzhj 2774 2 signs sign NNS cord-005646-xhx9pzhj 2774 3 of of IN cord-005646-xhx9pzhj 2774 4 laryngeal laryngeal NN cord-005646-xhx9pzhj 2774 5 estridor estridor NNP cord-005646-xhx9pzhj 2774 6 and and CC cord-005646-xhx9pzhj 2774 7 a a DT cord-005646-xhx9pzhj 2774 8 Downes Downes NNP cord-005646-xhx9pzhj 2774 9 and and CC cord-005646-xhx9pzhj 2774 10 Rafaelly Rafaelly NNP cord-005646-xhx9pzhj 2774 11 score score NN cord-005646-xhx9pzhj 2774 12 for for IN cord-005646-xhx9pzhj 2774 13 upper upper JJ cord-005646-xhx9pzhj 2774 14 respiratory respiratory JJ cord-005646-xhx9pzhj 2774 15 obstruction obstruction NN cord-005646-xhx9pzhj 2774 16 equal equal JJ cord-005646-xhx9pzhj 2774 17 to to IN cord-005646-xhx9pzhj 2774 18 or or CC cord-005646-xhx9pzhj 2774 19 higher high JJR cord-005646-xhx9pzhj 2774 20 than than IN cord-005646-xhx9pzhj 2774 21 4 4 CD cord-005646-xhx9pzhj 2774 22 Patients patient NNS cord-005646-xhx9pzhj 2774 23 with with IN cord-005646-xhx9pzhj 2774 24 primary primary JJ cord-005646-xhx9pzhj 2774 25 upper upper JJ cord-005646-xhx9pzhj 2774 26 respiratory respiratory JJ cord-005646-xhx9pzhj 2774 27 disease disease NN cord-005646-xhx9pzhj 2774 28 were be VBD cord-005646-xhx9pzhj 2774 29 excluded exclude VBN cord-005646-xhx9pzhj 2774 30 All all DT cord-005646-xhx9pzhj 2774 31 patients patient NNS cord-005646-xhx9pzhj 2774 32 enrolled enrol VBD cord-005646-xhx9pzhj 2774 33 reeieved reeieve VBN cord-005646-xhx9pzhj 2774 34 either either CC cord-005646-xhx9pzhj 2774 35 inhaled inhale VBN cord-005646-xhx9pzhj 2774 36 L l NN cord-005646-xhx9pzhj 2774 37 - - HYPH cord-005646-xhx9pzhj 2774 38 epinephrine epinephrine NN cord-005646-xhx9pzhj 2774 39 1 1 CD cord-005646-xhx9pzhj 2774 40 % % NN cord-005646-xhx9pzhj 2774 41 or or CC cord-005646-xhx9pzhj 2774 42 normal normal JJ cord-005646-xhx9pzhj 2774 43 saline saline NN cord-005646-xhx9pzhj 2774 44 . . . cord-005646-xhx9pzhj 2775 1 Dexametasene Dexametasene NNP cord-005646-xhx9pzhj 2775 2 ( ( -LRB- cord-005646-xhx9pzhj 2775 3 0,6 0,6 CD cord-005646-xhx9pzhj 2775 4 mg mg NNP cord-005646-xhx9pzhj 2775 5 / / SYM cord-005646-xhx9pzhj 2775 6 Kg Kg NNP cord-005646-xhx9pzhj 2775 7 / / SYM cord-005646-xhx9pzhj 2775 8 day day NN cord-005646-xhx9pzhj 2775 9 ) ) -RRB- cord-005646-xhx9pzhj 2775 10 was be VBD cord-005646-xhx9pzhj 2775 11 given give VBN cord-005646-xhx9pzhj 2775 12 to to IN cord-005646-xhx9pzhj 2775 13 all all DT cord-005646-xhx9pzhj 2775 14 patients patient NNS cord-005646-xhx9pzhj 2775 15 in in IN cord-005646-xhx9pzhj 2775 16 both both DT cord-005646-xhx9pzhj 2775 17 groups group NNS cord-005646-xhx9pzhj 2775 18 . . . cord-005646-xhx9pzhj 2776 1 After after IN cord-005646-xhx9pzhj 2776 2 2 2 CD cord-005646-xhx9pzhj 2776 3 inhalations inhalation NNS cord-005646-xhx9pzhj 2776 4 , , , cord-005646-xhx9pzhj 2776 5 aU au CD cord-005646-xhx9pzhj 2776 6 patients patient NNS cord-005646-xhx9pzhj 2776 7 were be VBD cord-005646-xhx9pzhj 2776 8 monitored monitor VBN cord-005646-xhx9pzhj 2776 9 for for IN cord-005646-xhx9pzhj 2776 10 a a DT cord-005646-xhx9pzhj 2776 11 period period NN cord-005646-xhx9pzhj 2776 12 of of IN cord-005646-xhx9pzhj 2776 13 1 1 CD cord-005646-xhx9pzhj 2776 14 - - SYM cord-005646-xhx9pzhj 2776 15 20 20 CD cord-005646-xhx9pzhj 2776 16 minutes minute NNS cord-005646-xhx9pzhj 2776 17 and and CC cord-005646-xhx9pzhj 2776 18 monitoring monitoring NN cord-005646-xhx9pzhj 2776 19 included include VBD cord-005646-xhx9pzhj 2776 20 cardiac cardiac JJ cord-005646-xhx9pzhj 2776 21 and and CC cord-005646-xhx9pzhj 2776 22 respiratory respiratory JJ cord-005646-xhx9pzhj 2776 23 rate rate NN cord-005646-xhx9pzhj 2776 24 , , , cord-005646-xhx9pzhj 2776 25 mean mean VBP cord-005646-xhx9pzhj 2776 26 arterial arterial JJ cord-005646-xhx9pzhj 2776 27 blood blood NN cord-005646-xhx9pzhj 2776 28 pressure pressure NN cord-005646-xhx9pzhj 2776 29 , , , cord-005646-xhx9pzhj 2776 30 arterial arterial JJ cord-005646-xhx9pzhj 2776 31 blood blood NN cord-005646-xhx9pzhj 2776 32 gases gas NNS cord-005646-xhx9pzhj 2776 33 and and CC cord-005646-xhx9pzhj 2776 34 the the DT cord-005646-xhx9pzhj 2776 35 Dowries Dowries NNPS cord-005646-xhx9pzhj 2776 36 and and CC cord-005646-xhx9pzhj 2776 37 Rafaelly Rafaelly NNP cord-005646-xhx9pzhj 2776 38 score score NN cord-005646-xhx9pzhj 2776 39 . . . cord-005646-xhx9pzhj 2777 1 Statistical statistical JJ cord-005646-xhx9pzhj 2777 2 analysis analysis NN cord-005646-xhx9pzhj 2777 3 included include VBD cord-005646-xhx9pzhj 2777 4 , , , cord-005646-xhx9pzhj 2777 5 Qui Qui NNP cord-005646-xhx9pzhj 2777 6 - - HYPH cord-005646-xhx9pzhj 2777 7 square square NNP cord-005646-xhx9pzhj 2777 8 with with IN cord-005646-xhx9pzhj 2777 9 the the DT cord-005646-xhx9pzhj 2777 10 Fisher Fisher NNP cord-005646-xhx9pzhj 2777 11 correction correction NN cord-005646-xhx9pzhj 2777 12 test test NN cord-005646-xhx9pzhj 2777 13 and and CC cord-005646-xhx9pzhj 2777 14 the the DT cord-005646-xhx9pzhj 2777 15 Z z NN cord-005646-xhx9pzhj 2777 16 - - HYPH cord-005646-xhx9pzhj 2777 17 test test NN cord-005646-xhx9pzhj 2777 18 for for IN cord-005646-xhx9pzhj 2777 19 paired pair VBN cord-005646-xhx9pzhj 2777 20 variables variable NNS cord-005646-xhx9pzhj 2777 21 . . . cord-005646-xhx9pzhj 2778 1 Thirty thirty CD cord-005646-xhx9pzhj 2778 2 eight eight CD cord-005646-xhx9pzhj 2778 3 patients patient NNS cord-005646-xhx9pzhj 2778 4 ( ( -LRB- cord-005646-xhx9pzhj 2778 5 13,1 13,1 CD cord-005646-xhx9pzhj 2778 6 % % NN cord-005646-xhx9pzhj 2778 7 ) ) -RRB- cord-005646-xhx9pzhj 2778 8 met meet VBD cord-005646-xhx9pzhj 2778 9 the the DT cord-005646-xhx9pzhj 2778 10 criteria criterion NNS cord-005646-xhx9pzhj 2778 11 for for IN cord-005646-xhx9pzhj 2778 12 enrollment enrollment NN cord-005646-xhx9pzhj 2778 13 , , , cord-005646-xhx9pzhj 2778 14 18 18 CD cord-005646-xhx9pzhj 2778 15 to to IN cord-005646-xhx9pzhj 2778 16 the the DT cord-005646-xhx9pzhj 2778 17 LE LE NNP cord-005646-xhx9pzhj 2778 18 group group NN cord-005646-xhx9pzhj 2778 19 and and CC cord-005646-xhx9pzhj 2778 20 20 20 CD cord-005646-xhx9pzhj 2778 21 to to IN cord-005646-xhx9pzhj 2778 22 the the DT cord-005646-xhx9pzhj 2778 23 placebo placebo NN cord-005646-xhx9pzhj 2778 24 group group NN cord-005646-xhx9pzhj 2778 25 . . . cord-005646-xhx9pzhj 2779 1 There there EX cord-005646-xhx9pzhj 2779 2 were be VBD cord-005646-xhx9pzhj 2779 3 no no DT cord-005646-xhx9pzhj 2779 4 significant significant JJ cord-005646-xhx9pzhj 2779 5 differences difference NNS cord-005646-xhx9pzhj 2779 6 in in IN cord-005646-xhx9pzhj 2779 7 both both DT cord-005646-xhx9pzhj 2779 8 groups group NNS cord-005646-xhx9pzhj 2779 9 in in IN cord-005646-xhx9pzhj 2779 10 regard regard NN cord-005646-xhx9pzhj 2779 11 to to IN cord-005646-xhx9pzhj 2779 12 age age NN cord-005646-xhx9pzhj 2779 13 , , , cord-005646-xhx9pzhj 2779 14 sex sex NN cord-005646-xhx9pzhj 2779 15 , , , cord-005646-xhx9pzhj 2779 16 initial initial JJ cord-005646-xhx9pzhj 2779 17 score score NN cord-005646-xhx9pzhj 2779 18 ( ( -LRB- cord-005646-xhx9pzhj 2779 19 5,05 5,05 CD cord-005646-xhx9pzhj 2779 20 x x SYM cord-005646-xhx9pzhj 2779 21 5,1 5,1 CD cord-005646-xhx9pzhj 2779 22 ) ) -RRB- cord-005646-xhx9pzhj 2779 23 and and CC cord-005646-xhx9pzhj 2779 24 endotracheal endotracheal NN cord-005646-xhx9pzhj 2779 25 tube tube NN cord-005646-xhx9pzhj 2779 26 diameter diameter NN cord-005646-xhx9pzhj 2779 27 . . . cord-005646-xhx9pzhj 2780 1 The the DT cord-005646-xhx9pzhj 2780 2 period period NN cord-005646-xhx9pzhj 2780 3 of of IN cord-005646-xhx9pzhj 2780 4 ventilatory ventilatory JJ cord-005646-xhx9pzhj 2780 5 support support NN cord-005646-xhx9pzhj 2780 6 and and CC cord-005646-xhx9pzhj 2780 7 tracheal tracheal JJ cord-005646-xhx9pzhj 2780 8 intubation intubation NN cord-005646-xhx9pzhj 2780 9 was be VBD cord-005646-xhx9pzhj 2780 10 significantly significantly RB cord-005646-xhx9pzhj 2780 11 higher high JJR cord-005646-xhx9pzhj 2780 12 in in IN cord-005646-xhx9pzhj 2780 13 the the DT cord-005646-xhx9pzhj 2780 14 LE LE NNP cord-005646-xhx9pzhj 2780 15 group group NN cord-005646-xhx9pzhj 2780 16 ( ( -LRB- cord-005646-xhx9pzhj 2780 17 8,06 8,06 CD cord-005646-xhx9pzhj 2780 18 x x SYM cord-005646-xhx9pzhj 2780 19 4,54 4,54 CD cord-005646-xhx9pzhj 2780 20 , , , cord-005646-xhx9pzhj 2780 21 p p NN cord-005646-xhx9pzhj 2780 22 = = SYM cord-005646-xhx9pzhj 2780 23 0,01 0,01 NN cord-005646-xhx9pzhj 2780 24 ) ) -RRB- cord-005646-xhx9pzhj 2780 25 . . . cord-005646-xhx9pzhj 2781 1 The the DT cord-005646-xhx9pzhj 2781 2 follow follow VB cord-005646-xhx9pzhj 2781 3 - - HYPH cord-005646-xhx9pzhj 2781 4 up up NN cord-005646-xhx9pzhj 2781 5 score score NN cord-005646-xhx9pzhj 2781 6 showed show VBD cord-005646-xhx9pzhj 2781 7 a a DT cord-005646-xhx9pzhj 2781 8 significant significant JJ cord-005646-xhx9pzhj 2781 9 drop drop NN cord-005646-xhx9pzhj 2781 10 only only RB cord-005646-xhx9pzhj 2781 11 at at IN cord-005646-xhx9pzhj 2781 12 30 30 CD cord-005646-xhx9pzhj 2781 13 minutes minute NNS cord-005646-xhx9pzhj 2781 14 after after IN cord-005646-xhx9pzhj 2781 15 the the DT cord-005646-xhx9pzhj 2781 16 inhalations inhalation NNS cord-005646-xhx9pzhj 2781 17 ( ( -LRB- cord-005646-xhx9pzhj 2781 18 p p NN cord-005646-xhx9pzhj 2781 19 = = SYM cord-005646-xhx9pzhj 2781 20 0,03 0,03 CD cord-005646-xhx9pzhj 2781 21 ) ) -RRB- cord-005646-xhx9pzhj 2781 22 . . . cord-005646-xhx9pzhj 2782 1 Re Re VBG cord-005646-xhx9pzhj 2782 2 - - NN cord-005646-xhx9pzhj 2782 3 intubation intubation NN cord-005646-xhx9pzhj 2782 4 due due IN cord-005646-xhx9pzhj 2782 5 to to IN cord-005646-xhx9pzhj 2782 6 laryngitis laryngitis NN cord-005646-xhx9pzhj 2782 7 , , , cord-005646-xhx9pzhj 2782 8 occured occur VBD cord-005646-xhx9pzhj 2782 9 in in IN cord-005646-xhx9pzhj 2782 10 1 1 CD cord-005646-xhx9pzhj 2782 11 patient patient NN cord-005646-xhx9pzhj 2782 12 of of IN cord-005646-xhx9pzhj 2782 13 the the DT cord-005646-xhx9pzhj 2782 14 LE LE NNP cord-005646-xhx9pzhj 2782 15 group group NN cord-005646-xhx9pzhj 2782 16 and and CC cord-005646-xhx9pzhj 2782 17 in in IN cord-005646-xhx9pzhj 2782 18 4 4 CD cord-005646-xhx9pzhj 2782 19 of of IN cord-005646-xhx9pzhj 2782 20 the the DT cord-005646-xhx9pzhj 2782 21 placebo placebo NN cord-005646-xhx9pzhj 2782 22 group group NN cord-005646-xhx9pzhj 2782 23 with with IN cord-005646-xhx9pzhj 2782 24 no no DT cord-005646-xhx9pzhj 2782 25 statistical statistical JJ cord-005646-xhx9pzhj 2782 26 sxgnificance sxgnificance NN cord-005646-xhx9pzhj 2782 27 ( ( -LRB- cord-005646-xhx9pzhj 2782 28 p p NN cord-005646-xhx9pzhj 2782 29 = = SYM cord-005646-xhx9pzhj 2782 30 0,2 0,2 CD cord-005646-xhx9pzhj 2782 31 ) ) -RRB- cord-005646-xhx9pzhj 2782 32 . . . cord-005646-xhx9pzhj 2783 1 No no DT cord-005646-xhx9pzhj 2783 2 difference difference NN cord-005646-xhx9pzhj 2783 3 was be VBD cord-005646-xhx9pzhj 2783 4 observed observe VBN cord-005646-xhx9pzhj 2783 5 on on IN cord-005646-xhx9pzhj 2783 6 the the DT cord-005646-xhx9pzhj 2783 7 monitored monitor VBN cord-005646-xhx9pzhj 2783 8 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 2783 9 variables variable NNS cord-005646-xhx9pzhj 2783 10 during during IN cord-005646-xhx9pzhj 2783 11 the the DT cord-005646-xhx9pzhj 2783 12 120 120 CD cord-005646-xhx9pzhj 2783 13 minutes minute NNS cord-005646-xhx9pzhj 2783 14 , , , cord-005646-xhx9pzhj 2783 15 except except IN cord-005646-xhx9pzhj 2783 16 for for IN cord-005646-xhx9pzhj 2783 17 the the DT cord-005646-xhx9pzhj 2783 18 mean mean JJ cord-005646-xhx9pzhj 2783 19 arterial arterial JJ cord-005646-xhx9pzhj 2783 20 pressure pressure NN cord-005646-xhx9pzhj 2783 21 at at IN cord-005646-xhx9pzhj 2783 22 60 60 CD cord-005646-xhx9pzhj 2783 23 minutes minute NNS cord-005646-xhx9pzhj 2783 24 , , , cord-005646-xhx9pzhj 2783 25 being be VBG cord-005646-xhx9pzhj 2783 26 heighar heighar NN cord-005646-xhx9pzhj 2783 27 on on IN cord-005646-xhx9pzhj 2783 28 the the DT cord-005646-xhx9pzhj 2783 29 placebo placebo NN cord-005646-xhx9pzhj 2783 30 group group NN cord-005646-xhx9pzhj 2783 31 ( ( -LRB- cord-005646-xhx9pzhj 2783 32 p p NN cord-005646-xhx9pzhj 2783 33 = = SYM cord-005646-xhx9pzhj 2783 34 0,05 0,05 NN cord-005646-xhx9pzhj 2783 35 ) ) -RRB- cord-005646-xhx9pzhj 2783 36 . . . cord-005646-xhx9pzhj 2784 1 We -PRON- PRP cord-005646-xhx9pzhj 2784 2 concluded conclude VBD cord-005646-xhx9pzhj 2784 3 that that IN cord-005646-xhx9pzhj 2784 4 , , , cord-005646-xhx9pzhj 2784 5 although although IN cord-005646-xhx9pzhj 2784 6 the the DT cord-005646-xhx9pzhj 2784 7 L l NN cord-005646-xhx9pzhj 2784 8 - - HYPH cord-005646-xhx9pzhj 2784 9 epinephrine epinephrine NN cord-005646-xhx9pzhj 2784 10 group group NN cord-005646-xhx9pzhj 2784 11 showed show VBD cord-005646-xhx9pzhj 2784 12 a a DT cord-005646-xhx9pzhj 2784 13 trend trend NN cord-005646-xhx9pzhj 2784 14 in in IN cord-005646-xhx9pzhj 2784 15 better well JJR cord-005646-xhx9pzhj 2784 16 scores score NNS cord-005646-xhx9pzhj 2784 17 post post NN cord-005646-xhx9pzhj 2784 18 - - JJ cord-005646-xhx9pzhj 2784 19 inhalation inhalation NN cord-005646-xhx9pzhj 2784 20 and and CC cord-005646-xhx9pzhj 2784 21 fewer few JJR cord-005646-xhx9pzhj 2784 22 re re NNS cord-005646-xhx9pzhj 2784 23 - - NNS cord-005646-xhx9pzhj 2784 24 intubations intubation NNS cord-005646-xhx9pzhj 2784 25 due due JJ cord-005646-xhx9pzhj 2784 26 to to IN cord-005646-xhx9pzhj 2784 27 laryngitis laryngitis NN cord-005646-xhx9pzhj 2784 28 , , , cord-005646-xhx9pzhj 2784 29 the the DT cord-005646-xhx9pzhj 2784 30 results result NNS cord-005646-xhx9pzhj 2784 31 were be VBD cord-005646-xhx9pzhj 2784 32 not not RB cord-005646-xhx9pzhj 2784 33 statistically statistically RB cord-005646-xhx9pzhj 2784 34 significant significant JJ cord-005646-xhx9pzhj 2784 35 . . . cord-005646-xhx9pzhj 2785 1 We -PRON- PRP cord-005646-xhx9pzhj 2785 2 especulate especulate VBP cord-005646-xhx9pzhj 2785 3 that that IN cord-005646-xhx9pzhj 2785 4 the the DT cord-005646-xhx9pzhj 2785 5 period period NN cord-005646-xhx9pzhj 2785 6 of of IN cord-005646-xhx9pzhj 2785 7 intubation intubation NN cord-005646-xhx9pzhj 2785 8 may may MD cord-005646-xhx9pzhj 2785 9 have have VB cord-005646-xhx9pzhj 2785 10 affected affect VBN cord-005646-xhx9pzhj 2785 11 our -PRON- PRP$ cord-005646-xhx9pzhj 2785 12 results result NNS cord-005646-xhx9pzhj 2785 13 . . . cord-005646-xhx9pzhj 2786 1 Similarlly similarlly RB cord-005646-xhx9pzhj 2786 2 there there EX cord-005646-xhx9pzhj 2786 3 were be VBD cord-005646-xhx9pzhj 2786 4 no no DT cord-005646-xhx9pzhj 2786 5 differences difference NNS cord-005646-xhx9pzhj 2786 6 in in IN cord-005646-xhx9pzhj 2786 7 the the DT cord-005646-xhx9pzhj 2786 8 incidence incidence NN cord-005646-xhx9pzhj 2786 9 of of IN cord-005646-xhx9pzhj 2786 10 adverse adverse JJ cord-005646-xhx9pzhj 2786 11 effects effect NNS cord-005646-xhx9pzhj 2786 12 between between IN cord-005646-xhx9pzhj 2786 13 both both DT cord-005646-xhx9pzhj 2786 14 groups group NNS cord-005646-xhx9pzhj 2786 15 . . . cord-005646-xhx9pzhj 2787 1 Objectives objective NNS cord-005646-xhx9pzhj 2787 2 : : : cord-005646-xhx9pzhj 2787 3 To to TO cord-005646-xhx9pzhj 2787 4 evaluate evaluate VB cord-005646-xhx9pzhj 2787 5 the the DT cord-005646-xhx9pzhj 2787 6 complications complication NNS cord-005646-xhx9pzhj 2787 7 of of IN cord-005646-xhx9pzhj 2787 8 endotracheal endotracheal JJ cord-005646-xhx9pzhj 2787 9 intubation intubation NN cord-005646-xhx9pzhj 2787 10 in in IN cord-005646-xhx9pzhj 2787 11 children child NNS cord-005646-xhx9pzhj 2787 12 with with IN cord-005646-xhx9pzhj 2787 13 upper upper JJ cord-005646-xhx9pzhj 2787 14 airway airway NN cord-005646-xhx9pzhj 2787 15 obstruction obstruction NN cord-005646-xhx9pzhj 2787 16 due due JJ cord-005646-xhx9pzhj 2787 17 to to IN cord-005646-xhx9pzhj 2787 18 epiglottitis epiglottitis NN cord-005646-xhx9pzhj 2787 19 or or CC cord-005646-xhx9pzhj 2787 20 croup croup NN cord-005646-xhx9pzhj 2787 21 . . . cord-005646-xhx9pzhj 2788 1 Methodes methode NNS cord-005646-xhx9pzhj 2788 2 : : : cord-005646-xhx9pzhj 2788 3 During during IN cord-005646-xhx9pzhj 2788 4 a a DT cord-005646-xhx9pzhj 2788 5 5 5 CD cord-005646-xhx9pzhj 2788 6 year year NN cord-005646-xhx9pzhj 2788 7 period period NN cord-005646-xhx9pzhj 2788 8 ( ( -LRB- cord-005646-xhx9pzhj 2788 9 1991 1991 CD cord-005646-xhx9pzhj 2788 10 -1995 -1995 WP cord-005646-xhx9pzhj 2788 11 ) ) -RRB- cord-005646-xhx9pzhj 2788 12 all all DT cord-005646-xhx9pzhj 2788 13 patients patient NNS cord-005646-xhx9pzhj 2788 14 with with IN cord-005646-xhx9pzhj 2788 15 epiglottifis epiglottifi NNS cord-005646-xhx9pzhj 2788 16 or or CC cord-005646-xhx9pzhj 2788 17 croup croup NN cord-005646-xhx9pzhj 2788 18 were be VBD cord-005646-xhx9pzhj 2788 19 reviewed review VBN cord-005646-xhx9pzhj 2788 20 to to TO cord-005646-xhx9pzhj 2788 21 determine determine VB cord-005646-xhx9pzhj 2788 22 the the DT cord-005646-xhx9pzhj 2788 23 complications complication NNS cord-005646-xhx9pzhj 2788 24 of of IN cord-005646-xhx9pzhj 2788 25 endotracheal endotracheal NN cord-005646-xhx9pzhj 2788 26 intubation intubation NN cord-005646-xhx9pzhj 2788 27 , , , cord-005646-xhx9pzhj 2788 28 especially especially RB cord-005646-xhx9pzhj 2788 29 upper upper JJ cord-005646-xhx9pzhj 2788 30 airway airway NN cord-005646-xhx9pzhj 2788 31 obstruction obstruction NN cord-005646-xhx9pzhj 2788 32 due due JJ cord-005646-xhx9pzhj 2788 33 to to IN cord-005646-xhx9pzhj 2788 34 granulomas granuloma NNS cord-005646-xhx9pzhj 2788 35 . . . cord-005646-xhx9pzhj 2789 1 Results result NNS cord-005646-xhx9pzhj 2789 2 : : : cord-005646-xhx9pzhj 2789 3 33 33 CD cord-005646-xhx9pzhj 2789 4 Patients patient NNS cord-005646-xhx9pzhj 2789 5 were be VBD cord-005646-xhx9pzhj 2789 6 reviewed review VBN cord-005646-xhx9pzhj 2789 7 . . . cord-005646-xhx9pzhj 2790 1 In in IN cord-005646-xhx9pzhj 2790 2 17 17 CD cord-005646-xhx9pzhj 2790 3 children child NNS cord-005646-xhx9pzhj 2790 4 ( ( -LRB- cord-005646-xhx9pzhj 2790 5 mean mean VB cord-005646-xhx9pzhj 2790 6 age age NN cord-005646-xhx9pzhj 2790 7 2.5 2.5 CD cord-005646-xhx9pzhj 2790 8 years year NNS cord-005646-xhx9pzhj 2790 9 ) ) -RRB- cord-005646-xhx9pzhj 2790 10 with with IN cord-005646-xhx9pzhj 2790 11 epiglottitis epiglottitis NNP cord-005646-xhx9pzhj 2790 12 the the DT cord-005646-xhx9pzhj 2790 13 mean mean JJ cord-005646-xhx9pzhj 2790 14 duration duration NN cord-005646-xhx9pzhj 2790 15 of of IN cord-005646-xhx9pzhj 2790 16 intubation intubation NN cord-005646-xhx9pzhj 2790 17 was be VBD cord-005646-xhx9pzhj 2790 18 4.0 4.0 CD cord-005646-xhx9pzhj 2790 19 days day NNS cord-005646-xhx9pzhj 2790 20 ( ( -LRB- cord-005646-xhx9pzhj 2790 21 3 3 CD cord-005646-xhx9pzhj 2790 22 -5 -5 CD cord-005646-xhx9pzhj 2790 23 ) ) -RRB- cord-005646-xhx9pzhj 2790 24 . . . cord-005646-xhx9pzhj 2791 1 No no DT cord-005646-xhx9pzhj 2791 2 complications complication NNS cord-005646-xhx9pzhj 2791 3 were be VBD cord-005646-xhx9pzhj 2791 4 seen see VBN cord-005646-xhx9pzhj 2791 5 . . . cord-005646-xhx9pzhj 2792 1 In in IN cord-005646-xhx9pzhj 2792 2 16 16 CD cord-005646-xhx9pzhj 2792 3 patients patient NNS cord-005646-xhx9pzhj 2792 4 ( ( -LRB- cord-005646-xhx9pzhj 2792 5 mean mean VB cord-005646-xhx9pzhj 2792 6 age age NN cord-005646-xhx9pzhj 2792 7 2.3 2.3 CD cord-005646-xhx9pzhj 2792 8 years year NNS cord-005646-xhx9pzhj 2792 9 ) ) -RRB- cord-005646-xhx9pzhj 2792 10 with with IN cord-005646-xhx9pzhj 2792 11 croup croup NN cord-005646-xhx9pzhj 2792 12 the the DT cord-005646-xhx9pzhj 2792 13 mean mean JJ cord-005646-xhx9pzhj 2792 14 duration duration NN cord-005646-xhx9pzhj 2792 15 of of IN cord-005646-xhx9pzhj 2792 16 intubation intubation NN cord-005646-xhx9pzhj 2792 17 until until IN cord-005646-xhx9pzhj 2792 18 the the DT cord-005646-xhx9pzhj 2792 19 first first JJ cord-005646-xhx9pzhj 2792 20 extubation extubation NN cord-005646-xhx9pzhj 2792 21 was be VBD cord-005646-xhx9pzhj 2792 22 8.1 8.1 CD cord-005646-xhx9pzhj 2792 23 days day NNS cord-005646-xhx9pzhj 2792 24 ( ( -LRB- cord-005646-xhx9pzhj 2792 25 1 1 CD cord-005646-xhx9pzhj 2792 26 -15 -15 CD cord-005646-xhx9pzhj 2792 27 days day NNS cord-005646-xhx9pzhj 2792 28 ) ) -RRB- cord-005646-xhx9pzhj 2792 29 . . . cord-005646-xhx9pzhj 2793 1 Elective elective JJ cord-005646-xhx9pzhj 2793 2 extubation extubation NN cord-005646-xhx9pzhj 2793 3 was be VBD cord-005646-xhx9pzhj 2793 4 performed perform VBN cord-005646-xhx9pzhj 2793 5 if if IN cord-005646-xhx9pzhj 2793 6 an an DT cord-005646-xhx9pzhj 2793 7 airleak airleak NN cord-005646-xhx9pzhj 2793 8 was be VBD cord-005646-xhx9pzhj 2793 9 present present JJ cord-005646-xhx9pzhj 2793 10 or or CC cord-005646-xhx9pzhj 2793 11 after after IN cord-005646-xhx9pzhj 2793 12 7 7 CD cord-005646-xhx9pzhj 2793 13 days day NNS cord-005646-xhx9pzhj 2793 14 without without IN cord-005646-xhx9pzhj 2793 15 airleak airleak NNP cord-005646-xhx9pzhj 2793 16 but but CC cord-005646-xhx9pzhj 2793 17 in in IN cord-005646-xhx9pzhj 2793 18 the the DT cord-005646-xhx9pzhj 2793 19 absence absence NN cord-005646-xhx9pzhj 2793 20 of of IN cord-005646-xhx9pzhj 2793 21 fever fever NN cord-005646-xhx9pzhj 2793 22 and and CC cord-005646-xhx9pzhj 2793 23 obvious obvious JJ cord-005646-xhx9pzhj 2793 24 secretion secretion NN cord-005646-xhx9pzhj 2793 25 . . . cord-005646-xhx9pzhj 2794 1 Reintubation Reintubation NNP cord-005646-xhx9pzhj 2794 2 was be VBD cord-005646-xhx9pzhj 2794 3 not not RB cord-005646-xhx9pzhj 2794 4 necessary necessary JJ cord-005646-xhx9pzhj 2794 5 in in IN cord-005646-xhx9pzhj 2794 6 10 10 CD cord-005646-xhx9pzhj 2794 7 children child NNS cord-005646-xhx9pzhj 2794 8 ( ( -LRB- cord-005646-xhx9pzhj 2794 9 62.5 62.5 CD cord-005646-xhx9pzhj 2794 10 % % NN cord-005646-xhx9pzhj 2794 11 ) ) -RRB- cord-005646-xhx9pzhj 2794 12 . . . cord-005646-xhx9pzhj 2795 1 In in IN cord-005646-xhx9pzhj 2795 2 this this DT cord-005646-xhx9pzhj 2795 3 group group NN cord-005646-xhx9pzhj 2795 4 the the DT cord-005646-xhx9pzhj 2795 5 mean mean JJ cord-005646-xhx9pzhj 2795 6 duration duration NN cord-005646-xhx9pzhj 2795 7 of of IN cord-005646-xhx9pzhj 2795 8 intubation intubation NN cord-005646-xhx9pzhj 2795 9 was be VBD cord-005646-xhx9pzhj 2795 10 6.4 6.4 CD cord-005646-xhx9pzhj 2795 11 days day NNS cord-005646-xhx9pzhj 2795 12 ( ( -LRB- cord-005646-xhx9pzhj 2795 13 1 1 CD cord-005646-xhx9pzhj 2795 14 -12 -12 CD cord-005646-xhx9pzhj 2795 15 ) ) -RRB- cord-005646-xhx9pzhj 2795 16 . . . cord-005646-xhx9pzhj 2796 1 In in IN cord-005646-xhx9pzhj 2796 2 6 6 CD cord-005646-xhx9pzhj 2796 3 patients patient NNS cord-005646-xhx9pzhj 2796 4 ( ( -LRB- cord-005646-xhx9pzhj 2796 5 37.5 37.5 CD cord-005646-xhx9pzhj 2796 6 % % NN cord-005646-xhx9pzhj 2796 7 ) ) -RRB- cord-005646-xhx9pzhj 2796 8 reintubation reintubation NN cord-005646-xhx9pzhj 2796 9 was be VBD cord-005646-xhx9pzhj 2796 10 necessary necessary JJ cord-005646-xhx9pzhj 2796 11 because because IN cord-005646-xhx9pzhj 2796 12 of of IN cord-005646-xhx9pzhj 2796 13 severe severe JJ cord-005646-xhx9pzhj 2796 14 upper upper JJ cord-005646-xhx9pzhj 2796 15 airway airway NN cord-005646-xhx9pzhj 2796 16 obstruction obstruction NN cord-005646-xhx9pzhj 2796 17 due due JJ cord-005646-xhx9pzhj 2796 18 to to IN cord-005646-xhx9pzhj 2796 19 granulomas granuloma NNS cord-005646-xhx9pzhj 2796 20 . . . cord-005646-xhx9pzhj 2797 1 Mean mean JJ cord-005646-xhx9pzhj 2797 2 duration duration NN cord-005646-xhx9pzhj 2797 3 of of IN cord-005646-xhx9pzhj 2797 4 intubation intubation NN cord-005646-xhx9pzhj 2797 5 until until IN cord-005646-xhx9pzhj 2797 6 the the DT cord-005646-xhx9pzhj 2797 7 first first JJ cord-005646-xhx9pzhj 2797 8 extubation extubation NN cord-005646-xhx9pzhj 2797 9 was be VBD cord-005646-xhx9pzhj 2797 10 10.8 10.8 CD cord-005646-xhx9pzhj 2797 11 days day NNS cord-005646-xhx9pzhj 2797 12 ( ( -LRB- cord-005646-xhx9pzhj 2797 13 6 6 CD cord-005646-xhx9pzhj 2797 14 ) ) -RRB- cord-005646-xhx9pzhj 2797 15 ( ( -LRB- cord-005646-xhx9pzhj 2797 16 7 7 LS cord-005646-xhx9pzhj 2797 17 ) ) -RRB- cord-005646-xhx9pzhj 2797 18 ( ( -LRB- cord-005646-xhx9pzhj 2797 19 8) 8) NNP cord-005646-xhx9pzhj 2797 20 ( ( -LRB- cord-005646-xhx9pzhj 2797 21 9 9 CD cord-005646-xhx9pzhj 2797 22 ) ) -RRB- cord-005646-xhx9pzhj 2797 23 ( ( -LRB- cord-005646-xhx9pzhj 2797 24 10 10 CD cord-005646-xhx9pzhj 2797 25 ) ) -RRB- cord-005646-xhx9pzhj 2797 26 ( ( -LRB- cord-005646-xhx9pzhj 2797 27 11 11 CD cord-005646-xhx9pzhj 2797 28 ) ) -RRB- cord-005646-xhx9pzhj 2797 29 ( ( -LRB- cord-005646-xhx9pzhj 2797 30 12 12 CD cord-005646-xhx9pzhj 2797 31 ) ) -RRB- cord-005646-xhx9pzhj 2797 32 ( ( -LRB- cord-005646-xhx9pzhj 2797 33 13 13 CD cord-005646-xhx9pzhj 2797 34 ) ) -RRB- cord-005646-xhx9pzhj 2797 35 ( ( -LRB- cord-005646-xhx9pzhj 2797 36 14 14 CD cord-005646-xhx9pzhj 2797 37 ) ) -RRB- cord-005646-xhx9pzhj 2797 38 ( ( -LRB- cord-005646-xhx9pzhj 2797 39 15 15 CD cord-005646-xhx9pzhj 2797 40 ) ) -RRB- cord-005646-xhx9pzhj 2797 41 ( ( -LRB- cord-005646-xhx9pzhj 2797 42 16 16 CD cord-005646-xhx9pzhj 2797 43 ) ) -RRB- cord-005646-xhx9pzhj 2797 44 ( ( -LRB- cord-005646-xhx9pzhj 2797 45 17 17 CD cord-005646-xhx9pzhj 2797 46 ) ) -RRB- cord-005646-xhx9pzhj 2797 47 ( ( -LRB- cord-005646-xhx9pzhj 2797 48 18 18 CD cord-005646-xhx9pzhj 2797 49 ) ) -RRB- cord-005646-xhx9pzhj 2797 50 ( ( -LRB- cord-005646-xhx9pzhj 2797 51 19 19 CD cord-005646-xhx9pzhj 2797 52 ) ) -RRB- cord-005646-xhx9pzhj 2797 53 . . . cord-005646-xhx9pzhj 2798 1 There there EX cord-005646-xhx9pzhj 2798 2 seems seem VBZ cord-005646-xhx9pzhj 2798 3 to to TO cord-005646-xhx9pzhj 2798 4 be be VB cord-005646-xhx9pzhj 2798 5 a a DT cord-005646-xhx9pzhj 2798 6 difference difference NN cord-005646-xhx9pzhj 2798 7 in in IN cord-005646-xhx9pzhj 2798 8 duration duration NN cord-005646-xhx9pzhj 2798 9 of of IN cord-005646-xhx9pzhj 2798 10 intubation intubation NN cord-005646-xhx9pzhj 2798 11 between between IN cord-005646-xhx9pzhj 2798 12 these these DT cord-005646-xhx9pzhj 2798 13 two two CD cord-005646-xhx9pzhj 2798 14 groups group NNS cord-005646-xhx9pzhj 2798 15 with with IN cord-005646-xhx9pzhj 2798 16 croup croup NN cord-005646-xhx9pzhj 2798 17 , , , cord-005646-xhx9pzhj 2798 18 however however RB cord-005646-xhx9pzhj 2798 19 it -PRON- PRP cord-005646-xhx9pzhj 2798 20 is be VBZ cord-005646-xhx9pzhj 2798 21 not not RB cord-005646-xhx9pzhj 2798 22 significant significant JJ cord-005646-xhx9pzhj 2798 23 ( ( -LRB- cord-005646-xhx9pzhj 2798 24 p p NN cord-005646-xhx9pzhj 2798 25 > > XX cord-005646-xhx9pzhj 2798 26 0.1 0.1 CD cord-005646-xhx9pzhj 2798 27 ) ) -RRB- cord-005646-xhx9pzhj 2798 28 . . . cord-005646-xhx9pzhj 2799 1 All all PDT cord-005646-xhx9pzhj 2799 2 the the DT cord-005646-xhx9pzhj 2799 3 patients patient NNS cord-005646-xhx9pzhj 2799 4 with with IN cord-005646-xhx9pzhj 2799 5 granulomas granuloma NNS cord-005646-xhx9pzhj 2799 6 could could MD cord-005646-xhx9pzhj 2799 7 be be VB cord-005646-xhx9pzhj 2799 8 successfully successfully RB cord-005646-xhx9pzhj 2799 9 extubated extubate VBN cord-005646-xhx9pzhj 2799 10 after after IN cord-005646-xhx9pzhj 2799 11 microlaryngeal microlaryngeal NN cord-005646-xhx9pzhj 2799 12 surgery surgery NN cord-005646-xhx9pzhj 2799 13 , , , cord-005646-xhx9pzhj 2799 14 with with IN cord-005646-xhx9pzhj 2799 15 a a DT cord-005646-xhx9pzhj 2799 16 mean mean JJ cord-005646-xhx9pzhj 2799 17 intubation intubation NN cord-005646-xhx9pzhj 2799 18 period period NN cord-005646-xhx9pzhj 2799 19 of of IN cord-005646-xhx9pzhj 2799 20 35.3 35.3 CD cord-005646-xhx9pzhj 2799 21 days day NNS cord-005646-xhx9pzhj 2799 22 ( ( -LRB- cord-005646-xhx9pzhj 2799 23 21 21 CD cord-005646-xhx9pzhj 2799 24 -47 -47 CD cord-005646-xhx9pzhj 2799 25 ) ) -RRB- cord-005646-xhx9pzhj 2799 26 . . . cord-005646-xhx9pzhj 2800 1 revealed reveal VBD cord-005646-xhx9pzhj 2800 2 no no DT cord-005646-xhx9pzhj 2800 3 complications complication NNS cord-005646-xhx9pzhj 2800 4 , , , cord-005646-xhx9pzhj 2800 5 where where WRB cord-005646-xhx9pzhj 2800 6 as as IN cord-005646-xhx9pzhj 2800 7 endotracheal endotracheal JJ cord-005646-xhx9pzhj 2800 8 intubation intubation NN cord-005646-xhx9pzhj 2800 9 in in IN cord-005646-xhx9pzhj 2800 10 children child NNS cord-005646-xhx9pzhj 2800 11 suffering suffer VBG cord-005646-xhx9pzhj 2800 12 from from IN cord-005646-xhx9pzhj 2800 13 croup croup NN cord-005646-xhx9pzhj 2800 14 showed show VBD cord-005646-xhx9pzhj 2800 15 a a DT cord-005646-xhx9pzhj 2800 16 high high JJ cord-005646-xhx9pzhj 2800 17 incidence incidence NN cord-005646-xhx9pzhj 2800 18 ( ( -LRB- cord-005646-xhx9pzhj 2800 19 37.5 37.5 CD cord-005646-xhx9pzhj 2800 20 % % NN cord-005646-xhx9pzhj 2800 21 ) ) -RRB- cord-005646-xhx9pzhj 2800 22 of of IN cord-005646-xhx9pzhj 2800 23 granulomas granuloma NNS cord-005646-xhx9pzhj 2800 24 . . . cord-005646-xhx9pzhj 2801 1 However1 However1 NNP cord-005646-xhx9pzhj 2801 2 laryngeal laryngeal NN cord-005646-xhx9pzhj 2801 3 steepsis steepsi NNS cord-005646-xhx9pzhj 2801 4 and and CC cord-005646-xhx9pzhj 2801 5 other other JJ cord-005646-xhx9pzhj 2801 6 serious serious JJ cord-005646-xhx9pzhj 2801 7 complications complication NNS cord-005646-xhx9pzhj 2801 8 were be VBD cord-005646-xhx9pzhj 2801 9 not not RB cord-005646-xhx9pzhj 2801 10 sesn~ sesn~ NNS cord-005646-xhx9pzhj 2801 11 3 3 CD cord-005646-xhx9pzhj 2801 12 patients patient NNS cord-005646-xhx9pzhj 2801 13 ( ( -LRB- cord-005646-xhx9pzhj 2801 14 42 42 CD cord-005646-xhx9pzhj 2801 15 days day NNS cord-005646-xhx9pzhj 2801 16 averagely averagely RB cord-005646-xhx9pzhj 2801 17 ] ] -RRB- cord-005646-xhx9pzhj 2801 18 was be VBD cord-005646-xhx9pzhj 2801 19 obviously obviously RB cord-005646-xhx9pzhj 2801 20 seen see VBN cord-005646-xhx9pzhj 2801 21 in in IN cord-005646-xhx9pzhj 2801 22 ~he ~he NNP cord-005646-xhx9pzhj 2801 23 peak peak NNP cord-005646-xhx9pzhj 2801 24 = = SYM cord-005646-xhx9pzhj 2801 25 one one CD cord-005646-xhx9pzhj 2801 26 of of IN cord-005646-xhx9pzhj 2801 27 fl fl NNP cord-005646-xhx9pzhj 2801 28 , , , cord-005646-xhx9pzhj 2801 29 f2 f2 NNP cord-005646-xhx9pzhj 2801 30 resonance resonance NN cord-005646-xhx9pzhj 2801 31 and and CC cord-005646-xhx9pzhj 2801 32 in in IN cord-005646-xhx9pzhj 2801 33 the the DT cord-005646-xhx9pzhj 2801 34 zone zone NN cord-005646-xhx9pzhj 2801 35 of of IN cord-005646-xhx9pzhj 2801 36 high high JJ cord-005646-xhx9pzhj 2801 37 freq,-~ncy freq,-~ncy NN cord-005646-xhx9pzhj 2801 38 : : : cord-005646-xhx9pzhj 2802 1 r r LS cord-005646-xhx9pzhj 2802 2 , , , cord-005646-xhx9pzhj 2802 3 ~;~e ~;~e DT cord-005646-xhx9pzhj 2802 4 composition composition NN cord-005646-xhx9pzhj 2802 5 while while IN cord-005646-xhx9pzhj 2802 6 12 12 CD cord-005646-xhx9pzhj 2802 7 cases(3 cases(3 VBD cord-005646-xhx9pzhj 2802 8 day~ day~ CD cord-005646-xhx9pzhj 2803 1 average;y average;y NNP cord-005646-xhx9pzhj 2803 2 ] ] -RRB- cord-005646-xhx9pzhj 2804 1 : : : cord-005646-xhx9pzhj 2804 2 ~bowed ~bowed NFP cord-005646-xhx9pzhj 2804 3 no no DT cord-005646-xhx9pzhj 2804 4 abnormality abnormality NN cord-005646-xhx9pzhj 2804 5 both both CC cord-005646-xhx9pzhj 2804 6 clinically clinically RB cord-005646-xhx9pzhj 2804 7 and and CC cord-005646-xhx9pzhj 2804 8 Isryngoscopica!~y isryngoscopica!~y CD cord-005646-xhx9pzhj 2804 9 . . . cord-005646-xhx9pzhj 2804 10 7/10 7/10 CD cord-005646-xhx9pzhj 2804 11 patients patient NNS cord-005646-xhx9pzhj 2804 12 with with IN cord-005646-xhx9pzhj 2804 13 catheter catheter NN cord-005646-xhx9pzhj 2804 14 placement placement NN cord-005646-xhx9pzhj 2804 15 for for IN cord-005646-xhx9pzhj 2804 16 more more JJR cord-005646-xhx9pzhj 2804 17 than than IN cord-005646-xhx9pzhj 2804 18 6 6 CD cord-005646-xhx9pzhj 2804 19 week~ week~ NNP cord-005646-xhx9pzhj 2804 20 end end NN cord-005646-xhx9pzhj 2804 21 1126 1126 CD cord-005646-xhx9pzhj 2804 22 p p NN cord-005646-xhx9pzhj 2804 23 ~ ~ NFP cord-005646-xhx9pzhj 2804 24 tie,~ts tie,~ts NNP cord-005646-xhx9pzhj 2804 25 for for IN cord-005646-xhx9pzhj 2804 26 less less JJR cord-005646-xhx9pzhj 2804 27 than than IN cord-005646-xhx9pzhj 2804 28 5 5 CD cord-005646-xhx9pzhj 2804 29 weeks week NNS cord-005646-xhx9pzhj 2804 30 had have VBD cord-005646-xhx9pzhj 2804 31 t;~ryngeal t;~ryngeal DT cord-005646-xhx9pzhj 2804 32 abnormal abnormal JJ cord-005646-xhx9pzhj 2804 33 change change NN cord-005646-xhx9pzhj 2804 34 in in IN cord-005646-xhx9pzhj 2804 35 their -PRON- PRP$ cord-005646-xhx9pzhj 2804 36 larynges larynx NNS cord-005646-xhx9pzhj 2804 37 , , , cord-005646-xhx9pzhj 2804 38 Abnormal abnormal JJ cord-005646-xhx9pzhj 2804 39 changes change NNS cord-005646-xhx9pzhj 2804 40 of of IN cord-005646-xhx9pzhj 2804 41 sound sound JJ cord-005646-xhx9pzhj 2804 42 spectrogram spectrogram NN cord-005646-xhx9pzhj 2804 43 were be VBD cord-005646-xhx9pzhj 2804 44 all all DT cord-005646-xhx9pzhj 2804 45 seen see VBN cord-005646-xhx9pzhj 2804 46 in in IN cord-005646-xhx9pzhj 2804 47 3 3 CD cord-005646-xhx9pzhj 2804 48 patients patient NNS cord-005646-xhx9pzhj 2804 49 with with IN cord-005646-xhx9pzhj 2804 50 placement placement NN cord-005646-xhx9pzhj 2804 51 for for IN cord-005646-xhx9pzhj 2804 52 mope mope NN cord-005646-xhx9pzhj 2804 53 than than IN cord-005646-xhx9pzhj 2804 54 5 5 CD cord-005646-xhx9pzhj 2804 55 weeks week NNS cord-005646-xhx9pzhj 2804 56 . . . cord-005646-xhx9pzhj 2805 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 2805 2 data data NN cord-005646-xhx9pzhj 2805 3 suggest= suggest= NN cord-005646-xhx9pzhj 2806 1 Ca ca RB cord-005646-xhx9pzhj 2806 2 ] ] -RRB- cord-005646-xhx9pzhj 2806 3 the the DT cord-005646-xhx9pzhj 2806 4 complication complication NN cord-005646-xhx9pzhj 2806 5 of of IN cord-005646-xhx9pzhj 2806 6 endotracheal endotracheal JJ cord-005646-xhx9pzhj 2806 7 intubation intubation NN cord-005646-xhx9pzhj 2806 8 was be VBD cord-005646-xhx9pzhj 2806 9 increases increase NNS cord-005646-xhx9pzhj 2806 10 with with IN cord-005646-xhx9pzhj 2806 11 increasing increase VBG cord-005646-xhx9pzhj 2806 12 length length NN cord-005646-xhx9pzhj 2806 13 of of IN cord-005646-xhx9pzhj 2806 14 time time NN cord-005646-xhx9pzhj 2806 15 of of IN cord-005646-xhx9pzhj 2806 16 catheter catheter NN cord-005646-xhx9pzhj 2806 17 placsm placsm NNP cord-005646-xhx9pzhj 2806 18 . . . cord-005646-xhx9pzhj 2807 1 entjbut entjbut NNP cord-005646-xhx9pzhj 2807 2 aeriuoa aeriuoa NNP cord-005646-xhx9pzhj 2807 3 complication complication NN cord-005646-xhx9pzhj 2807 4 is be VBZ cord-005646-xhx9pzhj 2807 5 rare rare JJ cord-005646-xhx9pzhj 2807 6 i i PRP cord-005646-xhx9pzhj 2808 1 ( ( -LRB- cord-005646-xhx9pzhj 2808 2 b b LS cord-005646-xhx9pzhj 2808 3 ] ] -RRB- cord-005646-xhx9pzhj 2808 4 the the DT cord-005646-xhx9pzhj 2808 5 time time NN cord-005646-xhx9pzhj 2808 6 limit limit NN cord-005646-xhx9pzhj 2808 7 of of IN cord-005646-xhx9pzhj 2808 8 pernasal pernasal NNP cord-005646-xhx9pzhj 2808 9 endotraoheal endotraoheal NNP cord-005646-xhx9pzhj 2808 10 catheter catheter NN cord-005646-xhx9pzhj 2808 11 placement placement NN cord-005646-xhx9pzhj 2808 12 is be VBZ cord-005646-xhx9pzhj 2808 13 5 5 CD cord-005646-xhx9pzhj 2808 14 weeks week NNS cord-005646-xhx9pzhj 2808 15 within within IN cord-005646-xhx9pzhj 2808 16 which which WDT cord-005646-xhx9pzhj 2808 17 the the DT cord-005646-xhx9pzhj 2808 18 procedure procedure NN cord-005646-xhx9pzhj 2808 19 is be VBZ cord-005646-xhx9pzhj 2808 20 • • NNP cord-005646-xhx9pzhj 2808 21 comparatively comparatively RB cord-005646-xhx9pzhj 2808 22 safe safe JJ cord-005646-xhx9pzhj 2808 23 and and CC cord-005646-xhx9pzhj 2808 24 effective effective JJ cord-005646-xhx9pzhj 2808 25 means mean NNS cord-005646-xhx9pzhj 2808 26 for for IN cord-005646-xhx9pzhj 2808 27 maintaining maintain VBG cord-005646-xhx9pzhj 2808 28 e e NNP cord-005646-xhx9pzhj 2808 29 tong tong NNP cord-005646-xhx9pzhj 2808 30 term term NN cord-005646-xhx9pzhj 2808 31 artificial artificial JJ cord-005646-xhx9pzhj 2808 32 airway airway NN cord-005646-xhx9pzhj 2808 33 . . . cord-005646-xhx9pzhj 2809 1 In in IN cord-005646-xhx9pzhj 2809 2 a a DT cord-005646-xhx9pzhj 2809 3 6-year 6-year JJ cord-005646-xhx9pzhj 2809 4 period period NN cord-005646-xhx9pzhj 2809 5 ( ( -LRB- cord-005646-xhx9pzhj 2809 6 1986 1986 CD cord-005646-xhx9pzhj 2809 7 ) ) -RRB- cord-005646-xhx9pzhj 2809 8 ( ( -LRB- cord-005646-xhx9pzhj 2809 9 1987 1987 CD cord-005646-xhx9pzhj 2809 10 ) ) -RRB- cord-005646-xhx9pzhj 2809 11 ( ( -LRB- cord-005646-xhx9pzhj 2809 12 1988 1988 CD cord-005646-xhx9pzhj 2809 13 ) ) -RRB- cord-005646-xhx9pzhj 2809 14 ( ( -LRB- cord-005646-xhx9pzhj 2809 15 1989 1989 CD cord-005646-xhx9pzhj 2809 16 ) ) -RRB- cord-005646-xhx9pzhj 2809 17 ( ( -LRB- cord-005646-xhx9pzhj 2809 18 1990 1990 CD cord-005646-xhx9pzhj 2809 19 ) ) -RRB- cord-005646-xhx9pzhj 2809 20 ( ( -LRB- cord-005646-xhx9pzhj 2809 21 1991 1991 CD cord-005646-xhx9pzhj 2809 22 ) ) -RRB- cord-005646-xhx9pzhj 2809 23 ( ( -LRB- cord-005646-xhx9pzhj 2809 24 1992 1992 CD cord-005646-xhx9pzhj 2809 25 ) ) -RRB- cord-005646-xhx9pzhj 2809 26 we -PRON- PRP cord-005646-xhx9pzhj 2809 27 diagnosed diagnose VBD cord-005646-xhx9pzhj 2809 28 TBM TBM NNP cord-005646-xhx9pzhj 2809 29 as as IN cord-005646-xhx9pzhj 2809 30 an an DT cord-005646-xhx9pzhj 2809 31 apparent apparent JJ cord-005646-xhx9pzhj 2809 32 dilatation dilatation NN cord-005646-xhx9pzhj 2809 33 of of IN cord-005646-xhx9pzhj 2809 34 the the DT cord-005646-xhx9pzhj 2809 35 trachea trachea NN cord-005646-xhx9pzhj 2809 36 and and CC cord-005646-xhx9pzhj 2809 37 main main JJ cord-005646-xhx9pzhj 2809 38 bronchi bronchi NN cord-005646-xhx9pzhj 2810 1 ih ih NNP cord-005646-xhx9pzhj 2810 2 four four CD cord-005646-xhx9pzhj 2810 3 premature premature JJ cord-005646-xhx9pzhj 2810 4 infants infant NNS cord-005646-xhx9pzhj 2810 5 on on IN cord-005646-xhx9pzhj 2810 6 continued continue VBN cord-005646-xhx9pzhj 2810 7 MV MV NNP cord-005646-xhx9pzhj 2810 8 for for IN cord-005646-xhx9pzhj 2810 9 respiratory respiratory JJ cord-005646-xhx9pzhj 2810 10 distress distress NN cord-005646-xhx9pzhj 2810 11 syndrome syndrome NN cord-005646-xhx9pzhj 2810 12 ( ( -LRB- cord-005646-xhx9pzhj 2810 13 RDS RDS NNP cord-005646-xhx9pzhj 2810 14 ) ) -RRB- cord-005646-xhx9pzhj 2810 15 . . . cord-005646-xhx9pzhj 2811 1 The the DT cord-005646-xhx9pzhj 2811 2 infants infant NNS cord-005646-xhx9pzhj 2811 3 were be VBD cord-005646-xhx9pzhj 2811 4 three three CD cord-005646-xhx9pzhj 2811 5 boys boy NNS cord-005646-xhx9pzhj 2811 6 and and CC cord-005646-xhx9pzhj 2811 7 one one CD cord-005646-xhx9pzhj 2811 8 girl girl NN cord-005646-xhx9pzhj 2811 9 with with IN cord-005646-xhx9pzhj 2811 10 gestational gestational JJ cord-005646-xhx9pzhj 2811 11 age age NN cord-005646-xhx9pzhj 2811 12 ( ( -LRB- cord-005646-xhx9pzhj 2811 13 GA GA NNP cord-005646-xhx9pzhj 2811 14 ) ) -RRB- cord-005646-xhx9pzhj 2811 15 26 26 CD cord-005646-xhx9pzhj 2811 16 - - SYM cord-005646-xhx9pzhj 2811 17 33 33 CD cord-005646-xhx9pzhj 2811 18 weeks week NNS cord-005646-xhx9pzhj 2811 19 and and CC cord-005646-xhx9pzhj 2811 20 body body NN cord-005646-xhx9pzhj 2811 21 weight weight NN cord-005646-xhx9pzhj 2811 22 ( ( -LRB- cord-005646-xhx9pzhj 2811 23 BW BW NNP cord-005646-xhx9pzhj 2811 24 ) ) -RRB- cord-005646-xhx9pzhj 2811 25 1100 1100 CD cord-005646-xhx9pzhj 2811 26 - - SYM cord-005646-xhx9pzhj 2811 27 1965 1965 CD cord-005646-xhx9pzhj 2811 28 g. g. NNP cord-005646-xhx9pzhj 2811 29 MV MV NNP cord-005646-xhx9pzhj 2811 30 was be VBD cord-005646-xhx9pzhj 2811 31 provided provide VBN cord-005646-xhx9pzhj 2811 32 by by IN cord-005646-xhx9pzhj 2811 33 Bourns Bourns NNP cord-005646-xhx9pzhj 2811 34 2001 2001 CD cord-005646-xhx9pzhj 2811 35 CUB CUB NNP cord-005646-xhx9pzhj 2811 36 time time NN cord-005646-xhx9pzhj 2811 37 - - HYPH cord-005646-xhx9pzhj 2811 38 cycled cycle VBN cord-005646-xhx9pzhj 2811 39 and and CC cord-005646-xhx9pzhj 2811 40 pressure pressure NN cord-005646-xhx9pzhj 2811 41 - - HYPH cord-005646-xhx9pzhj 2811 42 limited limit VBN cord-005646-xhx9pzhj 2811 43 ventilator ventilator NN cord-005646-xhx9pzhj 2811 44 to to TO cord-005646-xhx9pzhj 2811 45 attain attain VB cord-005646-xhx9pzhj 2811 46 normal normal JJ cord-005646-xhx9pzhj 2811 47 gas gas NN cord-005646-xhx9pzhj 2811 48 tensions tension NNS cord-005646-xhx9pzhj 2811 49 . . . cord-005646-xhx9pzhj 2812 1 No no DT cord-005646-xhx9pzhj 2812 2 jet jet NN cord-005646-xhx9pzhj 2812 3 ventilation ventilation NN cord-005646-xhx9pzhj 2812 4 was be VBD cord-005646-xhx9pzhj 2812 5 used use VBN cord-005646-xhx9pzhj 2812 6 . . . cord-005646-xhx9pzhj 2813 1 Chest chest NN cord-005646-xhx9pzhj 2813 2 radiographs radiograph NNS cord-005646-xhx9pzhj 2813 3 were be VBD cord-005646-xhx9pzhj 2813 4 reviewed review VBN cord-005646-xhx9pzhj 2813 5 for for IN cord-005646-xhx9pzhj 2813 6 a a DT cord-005646-xhx9pzhj 2813 7 complete complete JJ cord-005646-xhx9pzhj 2813 8 evaluation evaluation NN cord-005646-xhx9pzhj 2813 9 , , , cord-005646-xhx9pzhj 2813 10 and and CC cord-005646-xhx9pzhj 2813 11 for for IN cord-005646-xhx9pzhj 2813 12 the the DT cord-005646-xhx9pzhj 2813 13 evaluation evaluation NN cord-005646-xhx9pzhj 2813 14 of of IN cord-005646-xhx9pzhj 2813 15 the the DT cord-005646-xhx9pzhj 2813 16 airway airway NN cord-005646-xhx9pzhj 2813 17 . . . cord-005646-xhx9pzhj 2814 1 After after IN cord-005646-xhx9pzhj 2814 2 the the DT cord-005646-xhx9pzhj 2814 3 intial intial JJ cord-005646-xhx9pzhj 2814 4 subjective subjective JJ cord-005646-xhx9pzhj 2814 5 diagnosis diagnosis NN cord-005646-xhx9pzhj 2814 6 of of IN cord-005646-xhx9pzhj 2814 7 TBM TBM NNP cord-005646-xhx9pzhj 2814 8 , , , cord-005646-xhx9pzhj 2814 9 the the DT cord-005646-xhx9pzhj 2814 10 width width NN cord-005646-xhx9pzhj 2814 11 of of IN cord-005646-xhx9pzhj 2814 12 the the DT cord-005646-xhx9pzhj 2814 13 tracheal tracheal JJ cord-005646-xhx9pzhj 2814 14 and and CC cord-005646-xhx9pzhj 2814 15 main main JJ cord-005646-xhx9pzhj 2814 16 bronchial bronchial JJ cord-005646-xhx9pzhj 2814 17 air air NN cord-005646-xhx9pzhj 2814 18 column column NN cord-005646-xhx9pzhj 2814 19 was be VBD cord-005646-xhx9pzhj 2814 20 measured measure VBN cord-005646-xhx9pzhj 2814 21 at at IN cord-005646-xhx9pzhj 2814 22 the the DT cord-005646-xhx9pzhj 2814 23 lower low JJR cord-005646-xhx9pzhj 2814 24 level level NN cord-005646-xhx9pzhj 2814 25 of of IN cord-005646-xhx9pzhj 2814 26 the the DT cord-005646-xhx9pzhj 2814 27 first first JJ cord-005646-xhx9pzhj 2814 28 and and CC cord-005646-xhx9pzhj 2814 29 the the DT cord-005646-xhx9pzhj 2814 30 third third JJ cord-005646-xhx9pzhj 2814 31 thoracic thoracic JJ cord-005646-xhx9pzhj 2814 32 vertebal vertebal NNP cord-005646-xhx9pzhj 2814 33 body body NN cord-005646-xhx9pzhj 2814 34 iT1 iT1 NNP cord-005646-xhx9pzhj 2814 35 , , , cord-005646-xhx9pzhj 2814 36 T3 T3 NNP cord-005646-xhx9pzhj 2814 37 ) ) -RRB- cord-005646-xhx9pzhj 2814 38 and and CC cord-005646-xhx9pzhj 2814 39 near near IN cord-005646-xhx9pzhj 2814 40 the the DT cord-005646-xhx9pzhj 2814 41 carina carina NNP cord-005646-xhx9pzhj 2814 42 ; ; : cord-005646-xhx9pzhj 2814 43 the the DT cord-005646-xhx9pzhj 2814 44 width width NN cord-005646-xhx9pzhj 2814 45 of of IN cord-005646-xhx9pzhj 2814 46 the the DT cord-005646-xhx9pzhj 2814 47 main main JJ cord-005646-xhx9pzhj 2814 48 bronchi bronchi NN cord-005646-xhx9pzhj 2814 49 below below IN cord-005646-xhx9pzhj 2814 50 the the DT cord-005646-xhx9pzhj 2814 51 carina carina NNP cord-005646-xhx9pzhj 2814 52 was be VBD cord-005646-xhx9pzhj 2814 53 also also RB cord-005646-xhx9pzhj 2814 54 measured measure VBN cord-005646-xhx9pzhj 2814 55 . . . cord-005646-xhx9pzhj 2815 1 In in IN cord-005646-xhx9pzhj 2815 2 all all DT cord-005646-xhx9pzhj 2815 3 infants infant NNS cord-005646-xhx9pzhj 2815 4 , , , cord-005646-xhx9pzhj 2815 5 TBM TBM NNP cord-005646-xhx9pzhj 2815 6 became become VBD cord-005646-xhx9pzhj 2815 7 apparent apparent JJ cord-005646-xhx9pzhj 2815 8 close close RB cord-005646-xhx9pzhj 2815 9 to to IN cord-005646-xhx9pzhj 2815 10 the the DT cord-005646-xhx9pzhj 2815 11 20lh 20lh JJ cord-005646-xhx9pzhj 2815 12 day day NN cord-005646-xhx9pzhj 2815 13 , , , cord-005646-xhx9pzhj 2815 14 that that RB cord-005646-xhx9pzhj 2815 15 is is RB cord-005646-xhx9pzhj 2815 16 , , , cord-005646-xhx9pzhj 2815 17 after after IN cord-005646-xhx9pzhj 2815 18 2 2 CD cord-005646-xhx9pzhj 2815 19 - - SYM cord-005646-xhx9pzhj 2815 20 3 3 CD cord-005646-xhx9pzhj 2815 21 weeks week NNS cord-005646-xhx9pzhj 2815 22 of of IN cord-005646-xhx9pzhj 2815 23 MV MV NNP cord-005646-xhx9pzhj 2815 24 . . . cord-005646-xhx9pzhj 2816 1 Therefore therefore RB cord-005646-xhx9pzhj 2816 2 , , , cord-005646-xhx9pzhj 2816 3 for for IN cord-005646-xhx9pzhj 2816 4 the the DT cord-005646-xhx9pzhj 2816 5 time time NN cord-005646-xhx9pzhj 2816 6 period period NN cord-005646-xhx9pzhj 2816 7 from from IN cord-005646-xhx9pzhj 2816 8 birth birth NN cord-005646-xhx9pzhj 2816 9 to to IN cord-005646-xhx9pzhj 2816 10 the the DT cord-005646-xhx9pzhj 2816 11 20th 20th JJ cord-005646-xhx9pzhj 2816 12 day day NN cord-005646-xhx9pzhj 2816 13 the the DT cord-005646-xhx9pzhj 2816 14 following follow VBG cord-005646-xhx9pzhj 2816 15 ventilatory ventilatory NN cord-005646-xhx9pzhj 2816 16 parameters parameter NNS cord-005646-xhx9pzhj 2816 17 were be VBD cord-005646-xhx9pzhj 2816 18 reviewed review VBN cord-005646-xhx9pzhj 2816 19 and and CC cord-005646-xhx9pzhj 2816 20 analyzed analyze VBN cord-005646-xhx9pzhj 2816 21 : : : cord-005646-xhx9pzhj 2816 22 ( ( -LRB- cord-005646-xhx9pzhj 2816 23 1 1 LS cord-005646-xhx9pzhj 2816 24 ) ) -RRB- cord-005646-xhx9pzhj 2816 25 the the DT cord-005646-xhx9pzhj 2816 26 percentage percentage NN cord-005646-xhx9pzhj 2816 27 of of IN cord-005646-xhx9pzhj 2816 28 total total JJ cord-005646-xhx9pzhj 2816 29 ventilation ventilation NN cord-005646-xhx9pzhj 2816 30 time time NN cord-005646-xhx9pzhj 2816 31 when when WRB cord-005646-xhx9pzhj 2816 32 more more JJR cord-005646-xhx9pzhj 2816 33 than than IN cord-005646-xhx9pzhj 2816 34 40 40 CD cord-005646-xhx9pzhj 2816 35 % % NN cord-005646-xhx9pzhj 2816 36 O2 o2 NN cord-005646-xhx9pzhj 2816 37 concentration concentration NN cord-005646-xhx9pzhj 2816 38 was be VBD cord-005646-xhx9pzhj 2816 39 required require VBN cord-005646-xhx9pzhj 2816 40 , , , cord-005646-xhx9pzhj 2816 41 ( ( -LRB- cord-005646-xhx9pzhj 2816 42 2 2 LS cord-005646-xhx9pzhj 2816 43 ) ) -RRB- cord-005646-xhx9pzhj 2816 44 the the DT cord-005646-xhx9pzhj 2816 45 peak peak JJ cord-005646-xhx9pzhj 2816 46 inspiratory inspiratory JJ cord-005646-xhx9pzhj 2816 47 pressure pressure NN cord-005646-xhx9pzhj 2816 48 , , , cord-005646-xhx9pzhj 2816 49 ( ( -LRB- cord-005646-xhx9pzhj 2816 50 3 3 LS cord-005646-xhx9pzhj 2816 51 ) ) -RRB- cord-005646-xhx9pzhj 2816 52 the the DT cord-005646-xhx9pzhj 2816 53 positive positive JJ cord-005646-xhx9pzhj 2816 54 end end NN cord-005646-xhx9pzhj 2816 55 - - HYPH cord-005646-xhx9pzhj 2816 56 expiratory expiratory NN cord-005646-xhx9pzhj 2816 57 pressure pressure NN cord-005646-xhx9pzhj 2816 58 , , , cord-005646-xhx9pzhj 2816 59 and and CC cord-005646-xhx9pzhj 2816 60 ( ( -LRB- cord-005646-xhx9pzhj 2816 61 4 4 LS cord-005646-xhx9pzhj 2816 62 ) ) -RRB- cord-005646-xhx9pzhj 2816 63 the the DT cord-005646-xhx9pzhj 2816 64 duration duration NN cord-005646-xhx9pzhj 2816 65 of of IN cord-005646-xhx9pzhj 2816 66 high high JJ cord-005646-xhx9pzhj 2816 67 frequency frequency NN cord-005646-xhx9pzhj 2816 68 ventilation ventilation NN cord-005646-xhx9pzhj 2816 69 ( ( -LRB- cord-005646-xhx9pzhj 2816 70 80 80 CD cord-005646-xhx9pzhj 2816 71 - - SYM cord-005646-xhx9pzhj 2816 72 160 160 CD cord-005646-xhx9pzhj 2816 73 breaths breath NNS cord-005646-xhx9pzhj 2816 74 per per IN cord-005646-xhx9pzhj 2816 75 minute minute NN cord-005646-xhx9pzhj 2816 76 ) ) -RRB- cord-005646-xhx9pzhj 2816 77 . . . cord-005646-xhx9pzhj 2817 1 Also also RB cord-005646-xhx9pzhj 2817 2 noted note VBN cord-005646-xhx9pzhj 2817 3 were be VBD cord-005646-xhx9pzhj 2817 4 the the DT cord-005646-xhx9pzhj 2817 5 Apgar Apgar NNP cord-005646-xhx9pzhj 2817 6 scores score NNS cord-005646-xhx9pzhj 2817 7 ( ( -LRB- cord-005646-xhx9pzhj 2817 8 1 1 CD cord-005646-xhx9pzhj 2817 9 and and CC cord-005646-xhx9pzhj 2817 10 5 5 CD cord-005646-xhx9pzhj 2817 11 min min NN cord-005646-xhx9pzhj 2817 12 after after IN cord-005646-xhx9pzhj 2817 13 birth birth NN cord-005646-xhx9pzhj 2817 14 ) ) -RRB- cord-005646-xhx9pzhj 2817 15 , , , cord-005646-xhx9pzhj 2817 16 the the DT cord-005646-xhx9pzhj 2817 17 duration duration NN cord-005646-xhx9pzhj 2817 18 of of IN cord-005646-xhx9pzhj 2817 19 hypotension hypotension NN cord-005646-xhx9pzhj 2817 20 ( ( -LRB- cord-005646-xhx9pzhj 2817 21 systolic systolic JJ cord-005646-xhx9pzhj 2817 22 BP BP NNP cord-005646-xhx9pzhj 2817 23 below below IN cord-005646-xhx9pzhj 2817 24 40 40 CD cord-005646-xhx9pzhj 2817 25 mmHg mmHg NNS cord-005646-xhx9pzhj 2817 26 ) ) -RRB- cord-005646-xhx9pzhj 2817 27 and and CC cord-005646-xhx9pzhj 2817 28 circulatory circulatory JJ cord-005646-xhx9pzhj 2817 29 instability instability NN cord-005646-xhx9pzhj 2817 30 , , , cord-005646-xhx9pzhj 2817 31 the the DT cord-005646-xhx9pzhj 2817 32 presence presence NN cord-005646-xhx9pzhj 2817 33 of of IN cord-005646-xhx9pzhj 2817 34 systemic systemic JJ cord-005646-xhx9pzhj 2817 35 or or CC cord-005646-xhx9pzhj 2817 36 tracheal tracheal JJ cord-005646-xhx9pzhj 2817 37 conatal conatal JJ cord-005646-xhx9pzhj 2817 38 or or CC cord-005646-xhx9pzhj 2817 39 later later JJ cord-005646-xhx9pzhj 2817 40 infection infection NN cord-005646-xhx9pzhj 2817 41 , , , cord-005646-xhx9pzhj 2817 42 the the DT cord-005646-xhx9pzhj 2817 43 duration duration NN cord-005646-xhx9pzhj 2817 44 of of IN cord-005646-xhx9pzhj 2817 45 MV MV NNP cord-005646-xhx9pzhj 2817 46 , , , cord-005646-xhx9pzhj 2817 47 and and CC cord-005646-xhx9pzhj 2817 48 the the DT cord-005646-xhx9pzhj 2817 49 final final JJ cord-005646-xhx9pzhj 2817 50 clinical clinical JJ cord-005646-xhx9pzhj 2817 51 outcome outcome NN cord-005646-xhx9pzhj 2817 52 . . . cord-005646-xhx9pzhj 2818 1 The the DT cord-005646-xhx9pzhj 2818 2 records record NNS cord-005646-xhx9pzhj 2818 3 were be VBD cord-005646-xhx9pzhj 2818 4 also also RB cord-005646-xhx9pzhj 2818 5 reviewed review VBN cord-005646-xhx9pzhj 2818 6 for for IN cord-005646-xhx9pzhj 2818 7 other other JJ cord-005646-xhx9pzhj 2818 8 possible possible JJ cord-005646-xhx9pzhj 2818 9 pertinent pertinent JJ cord-005646-xhx9pzhj 2818 10 data datum NNS cord-005646-xhx9pzhj 2818 11 . . . cord-005646-xhx9pzhj 2819 1 RIGID rigid JJ cord-005646-xhx9pzhj 2819 2 RESPIRATORY respiratory JJ cord-005646-xhx9pzhj 2819 3 ENDOSCOPY endoscopy NN cord-005646-xhx9pzhj 2819 4 IN in IN cord-005646-xhx9pzhj 2819 5 CHILDREN child NNS cord-005646-xhx9pzhj 2819 6 Fraga Fraga NNP cord-005646-xhx9pzhj 2819 7 J J NNP cord-005646-xhx9pzhj 2819 8 , , , cord-005646-xhx9pzhj 2819 9 Amant6a Amant6a NNP cord-005646-xhx9pzhj 2819 10 S S NNP cord-005646-xhx9pzhj 2819 11 , , , cord-005646-xhx9pzhj 2819 12 Piva Piva NNP cord-005646-xhx9pzhj 2819 13 J J NNP cord-005646-xhx9pzhj 2819 14 , , , cord-005646-xhx9pzhj 2819 15 Nogueira Nogueira NNP cord-005646-xhx9pzhj 2819 16 A A NNP cord-005646-xhx9pzhj 2819 17 , , , cord-005646-xhx9pzhj 2820 1 Palombini Palombini NNP cord-005646-xhx9pzhj 2820 2 B. B. NNP cord-005646-xhx9pzhj 2820 3 Introduction introduction NN cord-005646-xhx9pzhj 2820 4 : : : cord-005646-xhx9pzhj 2821 1 The the DT cord-005646-xhx9pzhj 2821 2 respiratory respiratory JJ cord-005646-xhx9pzhj 2821 3 endoscopy endoscopy NN cord-005646-xhx9pzhj 2821 4 is be VBZ cord-005646-xhx9pzhj 2821 5 an an DT cord-005646-xhx9pzhj 2821 6 important important JJ cord-005646-xhx9pzhj 2821 7 procedure procedure NN cord-005646-xhx9pzhj 2821 8 to to TO cord-005646-xhx9pzhj 2821 9 diagnose diagnose VB cord-005646-xhx9pzhj 2821 10 and and CC cord-005646-xhx9pzhj 2821 11 treat treat VB cord-005646-xhx9pzhj 2821 12 many many JJ cord-005646-xhx9pzhj 2821 13 airway airway NN cord-005646-xhx9pzhj 2821 14 's 's POS cord-005646-xhx9pzhj 2821 15 diseases disease NNS cord-005646-xhx9pzhj 2821 16 in in IN cord-005646-xhx9pzhj 2821 17 children child NNS cord-005646-xhx9pzhj 2821 18 . . . cord-005646-xhx9pzhj 2822 1 Although although IN cord-005646-xhx9pzhj 2822 2 have have VBP cord-005646-xhx9pzhj 2822 3 had have VBN cord-005646-xhx9pzhj 2822 4 advances advance NNS cord-005646-xhx9pzhj 2822 5 in in IN cord-005646-xhx9pzhj 2822 6 radiologic radiologic JJ cord-005646-xhx9pzhj 2822 7 investigation investigation NN cord-005646-xhx9pzhj 2822 8 exams exam NNS cord-005646-xhx9pzhj 2822 9 and and CC cord-005646-xhx9pzhj 2822 10 pulmonary pulmonary JJ cord-005646-xhx9pzhj 2822 11 function function NN cord-005646-xhx9pzhj 2822 12 tests test NNS cord-005646-xhx9pzhj 2822 13 , , , cord-005646-xhx9pzhj 2822 14 the the DT cord-005646-xhx9pzhj 2822 15 direct direct JJ cord-005646-xhx9pzhj 2822 16 anatomic anatomic JJ cord-005646-xhx9pzhj 2822 17 visualization visualization NN cord-005646-xhx9pzhj 2822 18 of of IN cord-005646-xhx9pzhj 2822 19 airway airway NN cord-005646-xhx9pzhj 2822 20 is be VBZ cord-005646-xhx9pzhj 2822 21 important important JJ cord-005646-xhx9pzhj 2822 22 to to IN cord-005646-xhx9pzhj 2822 23 the the DT cord-005646-xhx9pzhj 2822 24 management management NN cord-005646-xhx9pzhj 2822 25 of of IN cord-005646-xhx9pzhj 2822 26 many many JJ cord-005646-xhx9pzhj 2822 27 respiratory respiratory JJ cord-005646-xhx9pzhj 2822 28 problems problem NNS cord-005646-xhx9pzhj 2822 29 . . . cord-005646-xhx9pzhj 2823 1 Objective objective NN cord-005646-xhx9pzhj 2823 2 : : : cord-005646-xhx9pzhj 2824 1 Evaluation evaluation VB cord-005646-xhx9pzhj 2824 2 the the DT cord-005646-xhx9pzhj 2824 3 respiratory respiratory JJ cord-005646-xhx9pzhj 2824 4 endoscopies endoscopy NNS cord-005646-xhx9pzhj 2824 5 performed perform VBN cord-005646-xhx9pzhj 2824 6 with with IN cord-005646-xhx9pzhj 2824 7 a a DT cord-005646-xhx9pzhj 2824 8 rigid rigid JJ cord-005646-xhx9pzhj 2824 9 bronchoscope bronchoscope NN cord-005646-xhx9pzhj 2824 10 in in IN cord-005646-xhx9pzhj 2824 11 a a DT cord-005646-xhx9pzhj 2824 12 pediatric pediatric JJ cord-005646-xhx9pzhj 2824 13 reference reference NN cord-005646-xhx9pzhj 2824 14 hospital hospital NN cord-005646-xhx9pzhj 2824 15 . . . cord-005646-xhx9pzhj 2825 1 Material material NN cord-005646-xhx9pzhj 2825 2 and and CC cord-005646-xhx9pzhj 2825 3 Methods method NNS cord-005646-xhx9pzhj 2826 1 : : : cord-005646-xhx9pzhj 2826 2 We -PRON- PRP cord-005646-xhx9pzhj 2826 3 study study VBP cord-005646-xhx9pzhj 2826 4 the the DT cord-005646-xhx9pzhj 2826 5 records record NNS cord-005646-xhx9pzhj 2826 6 of of IN cord-005646-xhx9pzhj 2826 7 all all DT cord-005646-xhx9pzhj 2826 8 children child NNS cord-005646-xhx9pzhj 2826 9 that that WDT cord-005646-xhx9pzhj 2826 10 were be VBD cord-005646-xhx9pzhj 2826 11 submitted submit VBN cord-005646-xhx9pzhj 2826 12 to to IN cord-005646-xhx9pzhj 2826 13 respiratory respiratory JJ cord-005646-xhx9pzhj 2826 14 endoscopy endoscopy NN cord-005646-xhx9pzhj 2826 15 under under IN cord-005646-xhx9pzhj 2826 16 general general JJ cord-005646-xhx9pzhj 2826 17 anesthesia anesthesia NN cord-005646-xhx9pzhj 2826 18 from from IN cord-005646-xhx9pzhj 2826 19 march march NNP cord-005646-xhx9pzhj 2826 20 1989 1989 CD cord-005646-xhx9pzhj 2826 21 to to IN cord-005646-xhx9pzhj 2826 22 march march NNP cord-005646-xhx9pzhj 2826 23 1992 1992 CD cord-005646-xhx9pzhj 2826 24 . . . cord-005646-xhx9pzhj 2827 1 Age age NN cord-005646-xhx9pzhj 2827 2 , , , cord-005646-xhx9pzhj 2827 3 sex sex NN cord-005646-xhx9pzhj 2827 4 , , , cord-005646-xhx9pzhj 2827 5 clinical clinical JJ cord-005646-xhx9pzhj 2827 6 to to TO cord-005646-xhx9pzhj 2827 7 indicate indicate VB cord-005646-xhx9pzhj 2827 8 the the DT cord-005646-xhx9pzhj 2827 9 procedure procedure NN cord-005646-xhx9pzhj 2827 10 , , , cord-005646-xhx9pzhj 2827 11 diagnosis diagnosis NN cord-005646-xhx9pzhj 2827 12 and and CC cord-005646-xhx9pzhj 2827 13 complications complication NNS cord-005646-xhx9pzhj 2827 14 of of IN cord-005646-xhx9pzhj 2827 15 endoscopy endoscopy NN cord-005646-xhx9pzhj 2827 16 were be VBD cord-005646-xhx9pzhj 2827 17 registered register VBN cord-005646-xhx9pzhj 2827 18 . . . cord-005646-xhx9pzhj 2828 1 Results result NNS cord-005646-xhx9pzhj 2828 2 : : : cord-005646-xhx9pzhj 2829 1 Three three CD cord-005646-xhx9pzhj 2829 2 hundred hundred CD cord-005646-xhx9pzhj 2829 3 and and CC cord-005646-xhx9pzhj 2829 4 fifty fifty CD cord-005646-xhx9pzhj 2829 5 six six CD cord-005646-xhx9pzhj 2829 6 respiratory respiratory JJ cord-005646-xhx9pzhj 2829 7 endoscopies endoscopy NNS cord-005646-xhx9pzhj 2829 8 were be VBD cord-005646-xhx9pzhj 2829 9 performed perform VBN cord-005646-xhx9pzhj 2829 10 . . . cord-005646-xhx9pzhj 2830 1 The the DT cord-005646-xhx9pzhj 2830 2 most most RBS cord-005646-xhx9pzhj 2830 3 common common JJ cord-005646-xhx9pzhj 2830 4 indications indication NNS cord-005646-xhx9pzhj 2830 5 for for IN cord-005646-xhx9pzhj 2830 6 endoscopy endoscopy NN cord-005646-xhx9pzhj 2830 7 were be VBD cord-005646-xhx9pzhj 2830 8 strider strider NN cord-005646-xhx9pzhj 2830 9 ( ( -LRB- cord-005646-xhx9pzhj 2830 10 52 52 CD cord-005646-xhx9pzhj 2830 11 % % NN cord-005646-xhx9pzhj 2830 12 ) ) -RRB- cord-005646-xhx9pzhj 2830 13 , , , cord-005646-xhx9pzhj 2830 14 suspected suspect VBN cord-005646-xhx9pzhj 2830 15 foreign foreign JJ cord-005646-xhx9pzhj 2830 16 body body NN cord-005646-xhx9pzhj 2830 17 ( ( -LRB- cord-005646-xhx9pzhj 2830 18 16 16 CD cord-005646-xhx9pzhj 2830 19 % % NN cord-005646-xhx9pzhj 2830 20 ) ) -RRB- cord-005646-xhx9pzhj 2830 21 , , , cord-005646-xhx9pzhj 2830 22 atelectasis atelectasis NN cord-005646-xhx9pzhj 2830 23 ( ( -LRB- cord-005646-xhx9pzhj 2830 24 16 16 CD cord-005646-xhx9pzhj 2830 25 % % NN cord-005646-xhx9pzhj 2830 26 ) ) -RRB- cord-005646-xhx9pzhj 2830 27 and and CC cord-005646-xhx9pzhj 2830 28 difficult difficult JJ cord-005646-xhx9pzhj 2830 29 tracheal tracheal NN cord-005646-xhx9pzhj 2830 30 extubation extubation NN cord-005646-xhx9pzhj 2830 31 ( ( -LRB- cord-005646-xhx9pzhj 2830 32 8 8 CD cord-005646-xhx9pzhj 2830 33 % % NN cord-005646-xhx9pzhj 2830 34 ) ) -RRB- cord-005646-xhx9pzhj 2830 35 . . . cord-005646-xhx9pzhj 2831 1 The the DT cord-005646-xhx9pzhj 2831 2 most most RBS cord-005646-xhx9pzhj 2831 3 frequent frequent JJ cord-005646-xhx9pzhj 2831 4 diagnosis diagnosis NN cord-005646-xhx9pzhj 2831 5 were be VBD cord-005646-xhx9pzhj 2831 6 laryngomalacia laryngomalacia NNS cord-005646-xhx9pzhj 2831 7 ( ( -LRB- cord-005646-xhx9pzhj 2831 8 36 36 CD cord-005646-xhx9pzhj 2831 9 % % NN cord-005646-xhx9pzhj 2831 10 ) ) -RRB- cord-005646-xhx9pzhj 2831 11 and and CC cord-005646-xhx9pzhj 2831 12 subglottic subglottic JJ cord-005646-xhx9pzhj 2831 13 stenosis stenosis NN cord-005646-xhx9pzhj 2831 14 ( ( -LRB- cord-005646-xhx9pzhj 2831 15 6 6 CD cord-005646-xhx9pzhj 2831 16 % % NN cord-005646-xhx9pzhj 2831 17 ) ) -RRB- cord-005646-xhx9pzhj 2831 18 in in IN cord-005646-xhx9pzhj 2831 19 the the DT cord-005646-xhx9pzhj 2831 20 glottic glottic JJ cord-005646-xhx9pzhj 2831 21 and and CC cord-005646-xhx9pzhj 2831 22 subglottic subglottic JJ cord-005646-xhx9pzhj 2831 23 areas area NNS cord-005646-xhx9pzhj 2831 24 , , , cord-005646-xhx9pzhj 2831 25 and and CC cord-005646-xhx9pzhj 2831 26 foreign foreign JJ cord-005646-xhx9pzhj 2831 27 body body NN cord-005646-xhx9pzhj 2831 28 ( ( -LRB- cord-005646-xhx9pzhj 2831 29 9 9 CD cord-005646-xhx9pzhj 2831 30 % % NN cord-005646-xhx9pzhj 2831 31 ) ) -RRB- cord-005646-xhx9pzhj 2831 32 and and CC cord-005646-xhx9pzhj 2831 33 tracheomalacia tracheomalacia NNS cord-005646-xhx9pzhj 2831 34 ( ( -LRB- cord-005646-xhx9pzhj 2831 35 7 7 CD cord-005646-xhx9pzhj 2831 36 % % NN cord-005646-xhx9pzhj 2831 37 ) ) -RRB- cord-005646-xhx9pzhj 2831 38 in in IN cord-005646-xhx9pzhj 2831 39 the the DT cord-005646-xhx9pzhj 2831 40 tracheobronchial tracheobronchial JJ cord-005646-xhx9pzhj 2831 41 area area NN cord-005646-xhx9pzhj 2831 42 . . . cord-005646-xhx9pzhj 2832 1 Normal normal JJ cord-005646-xhx9pzhj 2832 2 endoscopy endoscopy NN cord-005646-xhx9pzhj 2832 3 was be VBD cord-005646-xhx9pzhj 2832 4 performed perform VBN cord-005646-xhx9pzhj 2832 5 in in IN cord-005646-xhx9pzhj 2832 6 54 54 CD cord-005646-xhx9pzhj 2832 7 ( ( -LRB- cord-005646-xhx9pzhj 2832 8 21 21 CD cord-005646-xhx9pzhj 2832 9 % % NN cord-005646-xhx9pzhj 2832 10 ) ) -RRB- cord-005646-xhx9pzhj 2832 11 of of IN cord-005646-xhx9pzhj 2832 12 the the DT cord-005646-xhx9pzhj 2832 13 children child NNS cord-005646-xhx9pzhj 2832 14 . . . cord-005646-xhx9pzhj 2833 1 Only only RB cord-005646-xhx9pzhj 2833 2 three three CD cord-005646-xhx9pzhj 2833 3 slight slight JJ cord-005646-xhx9pzhj 2833 4 complications complication NNS cord-005646-xhx9pzhj 2833 5 of of IN cord-005646-xhx9pzhj 2833 6 the the DT cord-005646-xhx9pzhj 2833 7 endoscopy endoscopy NN cord-005646-xhx9pzhj 2833 8 were be VBD cord-005646-xhx9pzhj 2833 9 observed observe VBN cord-005646-xhx9pzhj 2833 10 . . . cord-005646-xhx9pzhj 2834 1 Two two CD cord-005646-xhx9pzhj 2834 2 patients patient NNS cord-005646-xhx9pzhj 2834 3 presented present VBD cord-005646-xhx9pzhj 2834 4 bradycardia bradycardia NN cord-005646-xhx9pzhj 2834 5 during during IN cord-005646-xhx9pzhj 2834 6 the the DT cord-005646-xhx9pzhj 2834 7 exam exam NN cord-005646-xhx9pzhj 2834 8 , , , cord-005646-xhx9pzhj 2834 9 and and CC cord-005646-xhx9pzhj 2834 10 the the DT cord-005646-xhx9pzhj 2834 11 third third JJ cord-005646-xhx9pzhj 2834 12 need need VB cord-005646-xhx9pzhj 2834 13 tracheal tracheal NN cord-005646-xhx9pzhj 2834 14 intubation intubation NN cord-005646-xhx9pzhj 2834 15 due due IN cord-005646-xhx9pzhj 2834 16 to to IN cord-005646-xhx9pzhj 2834 17 post post JJ cord-005646-xhx9pzhj 2834 18 - - JJ cord-005646-xhx9pzhj 2834 19 endoscopic endoscopic JJ cord-005646-xhx9pzhj 2834 20 subglottic subglottic JJ cord-005646-xhx9pzhj 2834 21 edema edema NN cord-005646-xhx9pzhj 2834 22 . . . cord-005646-xhx9pzhj 2835 1 Conclusion conclusion NN cord-005646-xhx9pzhj 2835 2 : : : cord-005646-xhx9pzhj 2836 1 The the DT cord-005646-xhx9pzhj 2836 2 rigid rigid JJ cord-005646-xhx9pzhj 2836 3 endoscopy endoscopy NN cord-005646-xhx9pzhj 2836 4 in in IN cord-005646-xhx9pzhj 2836 5 children child NNS cord-005646-xhx9pzhj 2836 6 is be VBZ cord-005646-xhx9pzhj 2836 7 efficient efficient JJ cord-005646-xhx9pzhj 2836 8 and and CC cord-005646-xhx9pzhj 2836 9 has have VBZ cord-005646-xhx9pzhj 2836 10 no no DT cord-005646-xhx9pzhj 2836 11 serious serious JJ cord-005646-xhx9pzhj 2836 12 complications complication NNS cord-005646-xhx9pzhj 2836 13 . . . cord-005646-xhx9pzhj 2837 1 Near near IN cord-005646-xhx9pzhj 2837 2 drowning drowning NN cord-005646-xhx9pzhj 2837 3 ; ; : cord-005646-xhx9pzhj 2837 4 Indicators indicator NNS cord-005646-xhx9pzhj 2837 5 of of IN cord-005646-xhx9pzhj 2837 6 acute acute JJ cord-005646-xhx9pzhj 2837 7 and and CC cord-005646-xhx9pzhj 2837 8 long long JJ cord-005646-xhx9pzhj 2837 9 term term NN cord-005646-xhx9pzhj 2837 10 prognosis prognosis NN cord-005646-xhx9pzhj 2838 1 Bernardien Bernardien NNP cord-005646-xhx9pzhj 2838 2 T.MJ T.MJ NNP cord-005646-xhx9pzhj 2838 3 . . . cord-005646-xhx9pzhj 2839 1 Thunnissen Thunnissen NNP cord-005646-xhx9pzhj 2839 2 t t NN cord-005646-xhx9pzhj 2839 3 , , , cord-005646-xhx9pzhj 2839 4 Reinoud Reinoud NNP cord-005646-xhx9pzhj 2839 5 J.B.J. J.B.J. NNP cord-005646-xhx9pzhj 2839 6 Gemke Gemke NNP cord-005646-xhx9pzhj 2839 7 1 1 CD cord-005646-xhx9pzhj 2839 8 , , , cord-005646-xhx9pzhj 2839 9 Loes Loes NNP cord-005646-xhx9pzhj 2839 10 Veenhuizer Veenhuizer NNP cord-005646-xhx9pzhj 2839 11 ? ? . cord-005646-xhx9pzhj 2839 12 , , , cord-005646-xhx9pzhj 2839 13 Krijn Krijn NNP cord-005646-xhx9pzhj 2839 14 Haasnoot Haasnoot NNP cord-005646-xhx9pzhj 2839 15 3 3 CD cord-005646-xhx9pzhj 2839 16 , , , cord-005646-xhx9pzhj 2839 17 A.Johannes A.Johannes NNP cord-005646-xhx9pzhj 2839 18 van van NNP cord-005646-xhx9pzhj 2839 19 Vugh0 Vugh0 NNP cord-005646-xhx9pzhj 2839 20 Department Department NNP cord-005646-xhx9pzhj 2839 21 of of IN cord-005646-xhx9pzhj 2839 22 pediatrics pediatric NNS cord-005646-xhx9pzhj 2839 23 , , , cord-005646-xhx9pzhj 2839 24 ~Wilhelmina ~wilhelmina ADD cord-005646-xhx9pzhj 2840 1 Children child NNS cord-005646-xhx9pzhj 2840 2 's 's POS cord-005646-xhx9pzhj 2840 3 Hospital Hospital NNP cord-005646-xhx9pzhj 2840 4 , , , cord-005646-xhx9pzhj 2840 5 Utrecht Utrecht NNP cord-005646-xhx9pzhj 2840 6 , , , cord-005646-xhx9pzhj 2840 7 2Sophia 2Sophia NNP cord-005646-xhx9pzhj 2840 8 Hospital Hospital NNP cord-005646-xhx9pzhj 2840 9 , , , cord-005646-xhx9pzhj 2840 10 Zwolle Zwolle NNP cord-005646-xhx9pzhj 2840 11 , , , cord-005646-xhx9pzhj 2840 12 and and CC cord-005646-xhx9pzhj 2840 13 ~Free ~Free NNP cord-005646-xhx9pzhj 2840 14 University University NNP cord-005646-xhx9pzhj 2840 15 Hospital Hospital NNP cord-005646-xhx9pzhj 2840 16 , , , cord-005646-xhx9pzhj 2840 17 Amsterdam Amsterdam NNP cord-005646-xhx9pzhj 2840 18 , , , cord-005646-xhx9pzhj 2840 19 The the DT cord-005646-xhx9pzhj 2840 20 Netherlands Netherlands NNP cord-005646-xhx9pzhj 2840 21 . . . cord-005646-xhx9pzhj 2841 1 In in IN cord-005646-xhx9pzhj 2841 2 this this DT cord-005646-xhx9pzhj 2841 3 retrospective retrospective JJ cord-005646-xhx9pzhj 2841 4 study study NN cord-005646-xhx9pzhj 2841 5 factors factor NNS cord-005646-xhx9pzhj 2841 6 that that WDT cord-005646-xhx9pzhj 2841 7 affect affect VBP cord-005646-xhx9pzhj 2841 8 short short JJ cord-005646-xhx9pzhj 2841 9 and and CC cord-005646-xhx9pzhj 2841 10 long long JJ cord-005646-xhx9pzhj 2841 11 term term NN cord-005646-xhx9pzhj 2841 12 prognosis prognosis NN cord-005646-xhx9pzhj 2841 13 after after IN cord-005646-xhx9pzhj 2841 14 submersion submersion NN cord-005646-xhx9pzhj 2841 15 were be VBD cord-005646-xhx9pzhj 2841 16 analysed analyse VBN cord-005646-xhx9pzhj 2841 17 . . . cord-005646-xhx9pzhj 2842 1 All all DT cord-005646-xhx9pzhj 2842 2 patients patient NNS cord-005646-xhx9pzhj 2842 3 that that WDT cord-005646-xhx9pzhj 2842 4 were be VBD cord-005646-xhx9pzhj 2842 5 admitted admit VBN cord-005646-xhx9pzhj 2842 6 to to IN cord-005646-xhx9pzhj 2842 7 a a DT cord-005646-xhx9pzhj 2842 8 tertiary tertiary JJ cord-005646-xhx9pzhj 2842 9 pediatric pediatric JJ cord-005646-xhx9pzhj 2842 10 ICU ICU NNP cord-005646-xhx9pzhj 2842 11 between between IN cord-005646-xhx9pzhj 2842 12 january january NNP cord-005646-xhx9pzhj 2842 13 I I NNP cord-005646-xhx9pzhj 2842 14 , , , cord-005646-xhx9pzhj 2842 15 1986 1986 CD cord-005646-xhx9pzhj 2842 16 and and CC cord-005646-xhx9pzhj 2842 17 january january NNP cord-005646-xhx9pzhj 2842 18 I I NNP cord-005646-xhx9pzhj 2842 19 , , , cord-005646-xhx9pzhj 2842 20 1992 1992 CD cord-005646-xhx9pzhj 2842 21 were be VBD cord-005646-xhx9pzhj 2842 22 included include VBN cord-005646-xhx9pzhj 2842 23 . . . cord-005646-xhx9pzhj 2843 1 Of of IN cord-005646-xhx9pzhj 2843 2 34 34 CD cord-005646-xhx9pzhj 2843 3 patients patient NNS cord-005646-xhx9pzhj 2843 4 , , , cord-005646-xhx9pzhj 2843 5 aged aged JJ cord-005646-xhx9pzhj 2843 6 0 0 CD cord-005646-xhx9pzhj 2843 7 - - SYM cord-005646-xhx9pzhj 2843 8 13 13 CD cord-005646-xhx9pzhj 2843 9 years year NNS cord-005646-xhx9pzhj 2843 10 , , , cord-005646-xhx9pzhj 2843 11 8 8 CD cord-005646-xhx9pzhj 2843 12 died die VBD cord-005646-xhx9pzhj 2843 13 in in IN cord-005646-xhx9pzhj 2843 14 the the DT cord-005646-xhx9pzhj 2843 15 ICU ICU NNP cord-005646-xhx9pzhj 2843 16 , , , cord-005646-xhx9pzhj 2843 17 one one CD cord-005646-xhx9pzhj 2843 18 after after IN cord-005646-xhx9pzhj 2843 19 hospital hospital NN cord-005646-xhx9pzhj 2843 20 discharge discharge NN cord-005646-xhx9pzhj 2843 21 . . . cord-005646-xhx9pzhj 2844 1 Survivors survivor NNS cord-005646-xhx9pzhj 2844 2 and and CC cord-005646-xhx9pzhj 2844 3 non non NNS cord-005646-xhx9pzhj 2844 4 - - NNS cord-005646-xhx9pzhj 2844 5 survivors survivor NNS cord-005646-xhx9pzhj 2844 6 showed show VBD cord-005646-xhx9pzhj 2844 7 significant significant JJ cord-005646-xhx9pzhj 2844 8 differences difference NNS cord-005646-xhx9pzhj 2844 9 with with IN cord-005646-xhx9pzhj 2844 10 respect respect NN cord-005646-xhx9pzhj 2844 11 to to IN cord-005646-xhx9pzhj 2844 12 central central JJ cord-005646-xhx9pzhj 2844 13 temperature temperature NN cord-005646-xhx9pzhj 2844 14 , , , cord-005646-xhx9pzhj 2844 15 pupillary pupillary JJ cord-005646-xhx9pzhj 2844 16 reactions reaction NNS cord-005646-xhx9pzhj 2844 17 , , , cord-005646-xhx9pzhj 2844 18 arterial arterial JJ cord-005646-xhx9pzhj 2844 19 pH ph NN cord-005646-xhx9pzhj 2844 20 , , , cord-005646-xhx9pzhj 2844 21 Pediatric Pediatric NNP cord-005646-xhx9pzhj 2844 22 Risk Risk NNP cord-005646-xhx9pzhj 2844 23 of of IN cord-005646-xhx9pzhj 2844 24 Mortality Mortality NNP cord-005646-xhx9pzhj 2844 25 ( ( -LRB- cord-005646-xhx9pzhj 2844 26 PRISM PRISM NNP cord-005646-xhx9pzhj 2844 27 ) ) -RRB- cord-005646-xhx9pzhj 2844 28 score score NN cord-005646-xhx9pzhj 2844 29 and and CC cord-005646-xhx9pzhj 2844 30 Therapeutic Therapeutic NNP cord-005646-xhx9pzhj 2844 31 Intervention Intervention NNP cord-005646-xhx9pzhj 2844 32 Scoring Scoring NNP cord-005646-xhx9pzhj 2844 33 System System NNP cord-005646-xhx9pzhj 2844 34 ( ( -LRB- cord-005646-xhx9pzhj 2844 35 TISS TISS NNP cord-005646-xhx9pzhj 2844 36 ) ) -RRB- cord-005646-xhx9pzhj 2844 37 upon upon IN cord-005646-xhx9pzhj 2844 38 admission admission NN cord-005646-xhx9pzhj 2844 39 ( ( -LRB- cord-005646-xhx9pzhj 2844 40 p p NN cord-005646-xhx9pzhj 2844 41 < < XX cord-005646-xhx9pzhj 2844 42 0.05 0.05 CD cord-005646-xhx9pzhj 2844 43 ) ) -RRB- cord-005646-xhx9pzhj 2844 44 . . . cord-005646-xhx9pzhj 2845 1 Non Non NNS cord-005646-xhx9pzhj 2845 2 - - NNS cord-005646-xhx9pzhj 2845 3 survivors survivor NNS cord-005646-xhx9pzhj 2845 4 more more RBR cord-005646-xhx9pzhj 2845 5 frequently frequently RB cord-005646-xhx9pzhj 2845 6 required require VBN cord-005646-xhx9pzhj 2845 7 mechanical mechanical JJ cord-005646-xhx9pzhj 2845 8 ventilation ventilation NN cord-005646-xhx9pzhj 2845 9 , , , cord-005646-xhx9pzhj 2845 10 bicarbonate bicarbonate NN cord-005646-xhx9pzhj 2845 11 administration administration NN cord-005646-xhx9pzhj 2845 12 and and CC cord-005646-xhx9pzhj 2845 13 active active JJ cord-005646-xhx9pzhj 2845 14 reheating reheating NN cord-005646-xhx9pzhj 2845 15 . . . cord-005646-xhx9pzhj 2846 1 ARDS ARDS NNP cord-005646-xhx9pzhj 2846 2 was be VBD cord-005646-xhx9pzhj 2846 3 seen see VBN cord-005646-xhx9pzhj 2846 4 in in IN cord-005646-xhx9pzhj 2846 5 22 22 CD cord-005646-xhx9pzhj 2846 6 patients patient NNS cord-005646-xhx9pzhj 2846 7 ( ( -LRB- cord-005646-xhx9pzhj 2846 8 65 65 CD cord-005646-xhx9pzhj 2846 9 % % NN cord-005646-xhx9pzhj 2846 10 ) ) -RRB- cord-005646-xhx9pzhj 2846 11 , , , cord-005646-xhx9pzhj 2846 12 invariably invariably RB cord-005646-xhx9pzhj 2846 13 within within IN cord-005646-xhx9pzhj 2846 14 6 6 CD cord-005646-xhx9pzhj 2846 15 hours hour NNS cord-005646-xhx9pzhj 2846 16 after after IN cord-005646-xhx9pzhj 2846 17 admission admission NN cord-005646-xhx9pzhj 2846 18 . . . cord-005646-xhx9pzhj 2847 1 No no DT cord-005646-xhx9pzhj 2847 2 patients patient NNS cord-005646-xhx9pzhj 2847 3 with with IN cord-005646-xhx9pzhj 2847 4 cardiac cardiac JJ cord-005646-xhx9pzhj 2847 5 arrest arrest NN cord-005646-xhx9pzhj 2847 6 on on IN cord-005646-xhx9pzhj 2847 7 " " `` cord-005646-xhx9pzhj 2847 8 admission admission NN cord-005646-xhx9pzhj 2847 9 snrvived snrvive VBN cord-005646-xhx9pzhj 2847 10 without without IN cord-005646-xhx9pzhj 2847 11 sequelae sequela NNS cord-005646-xhx9pzhj 2847 12 . . . cord-005646-xhx9pzhj 2848 1 Hypothermia hypothermia NN cord-005646-xhx9pzhj 2848 2 appeared appear VBD cord-005646-xhx9pzhj 2848 3 to to TO cord-005646-xhx9pzhj 2848 4 have have VB cord-005646-xhx9pzhj 2848 5 no no DT cord-005646-xhx9pzhj 2848 6 protective protective JJ cord-005646-xhx9pzhj 2848 7 effect effect NN cord-005646-xhx9pzhj 2848 8 on on IN cord-005646-xhx9pzhj 2848 9 hypoxic hypoxic JJ cord-005646-xhx9pzhj 2848 10 damage damage NN cord-005646-xhx9pzhj 2848 11 . . . cord-005646-xhx9pzhj 2849 1 Survivors survivor NNS cord-005646-xhx9pzhj 2849 2 with with IN cord-005646-xhx9pzhj 2849 3 persistent persistent JJ cord-005646-xhx9pzhj 2849 4 sequelae sequela NNS cord-005646-xhx9pzhj 2849 5 _ _ NN cord-005646-xhx9pzhj 2849 6 > > SYM cord-005646-xhx9pzhj 2849 7 6 6 CD cord-005646-xhx9pzhj 2849 8 months month NNS cord-005646-xhx9pzhj 2849 9 after after IN cord-005646-xhx9pzhj 2849 10 discharge discharge NN cord-005646-xhx9pzhj 2849 11 had have VBD cord-005646-xhx9pzhj 2849 12 significantly significantly RB cord-005646-xhx9pzhj 2849 13 higher high JJR cord-005646-xhx9pzhj 2849 14 PRISM prism NN cord-005646-xhx9pzhj 2849 15 and and CC cord-005646-xhx9pzhj 2849 16 T1SS T1SS NNP cord-005646-xhx9pzhj 2849 17 scores score NNS cord-005646-xhx9pzhj 2849 18 ( ( -LRB- cord-005646-xhx9pzhj 2849 19 mean mean VBP cord-005646-xhx9pzhj 2849 20 27 27 CD cord-005646-xhx9pzhj 2849 21 and and CC cord-005646-xhx9pzhj 2849 22 34 34 CD cord-005646-xhx9pzhj 2849 23 , , , cord-005646-xhx9pzhj 2849 24 respectively respectively RB cord-005646-xhx9pzhj 2849 25 ) ) -RRB- cord-005646-xhx9pzhj 2849 26 than than IN cord-005646-xhx9pzhj 2849 27 those those DT cord-005646-xhx9pzhj 2849 28 with with IN cord-005646-xhx9pzhj 2849 29 complete complete JJ cord-005646-xhx9pzhj 2849 30 recovery recovery NN cord-005646-xhx9pzhj 2849 31 ( ( -LRB- cord-005646-xhx9pzhj 2849 32 mean mean VB cord-005646-xhx9pzhj 2849 33 14 14 CD cord-005646-xhx9pzhj 2849 34 and and CC cord-005646-xhx9pzhj 2849 35 23 23 CD cord-005646-xhx9pzhj 2849 36 , , , cord-005646-xhx9pzhj 2849 37 respectively respectively RB cord-005646-xhx9pzhj 2849 38 ) ) -RRB- cord-005646-xhx9pzhj 2849 39 . . . cord-005646-xhx9pzhj 2850 1 Long long JJ cord-005646-xhx9pzhj 2850 2 term term NN cord-005646-xhx9pzhj 2850 3 cognitive cognitive JJ cord-005646-xhx9pzhj 2850 4 problems problem NNS cord-005646-xhx9pzhj 2850 5 were be VBD cord-005646-xhx9pzhj 2850 6 present present JJ cord-005646-xhx9pzhj 2850 7 in in IN cord-005646-xhx9pzhj 2850 8 7/25 7/25 CD cord-005646-xhx9pzhj 2850 9 survivors survivor NNS cord-005646-xhx9pzhj 2850 10 ( ( -LRB- cord-005646-xhx9pzhj 2850 11 28 28 CD cord-005646-xhx9pzhj 2850 12 % % NN cord-005646-xhx9pzhj 2850 13 ) ) -RRB- cord-005646-xhx9pzhj 2850 14 and and CC cord-005646-xhx9pzhj 2850 15 emotional emotional JJ cord-005646-xhx9pzhj 2850 16 disturbances disturbance NNS cord-005646-xhx9pzhj 2850 17 in in IN cord-005646-xhx9pzhj 2850 18 5/25 5/25 CD cord-005646-xhx9pzhj 2850 19 ( ( -LRB- cord-005646-xhx9pzhj 2850 20 20 20 CD cord-005646-xhx9pzhj 2850 21 % % NN cord-005646-xhx9pzhj 2850 22 ) ) -RRB- cord-005646-xhx9pzhj 2850 23 . . . cord-005646-xhx9pzhj 2851 1 In in IN cord-005646-xhx9pzhj 2851 2 conclusion conclusion NN cord-005646-xhx9pzhj 2851 3 , , , cord-005646-xhx9pzhj 2851 4 a a DT cord-005646-xhx9pzhj 2851 5 concise concise JJ cord-005646-xhx9pzhj 2851 6 number number NN cord-005646-xhx9pzhj 2851 7 of of IN cord-005646-xhx9pzhj 2851 8 clinical clinical JJ cord-005646-xhx9pzhj 2851 9 and and CC cord-005646-xhx9pzhj 2851 10 laboratory laboratory NN cord-005646-xhx9pzhj 2851 11 parameters parameter NNS cord-005646-xhx9pzhj 2851 12 , , , cord-005646-xhx9pzhj 2851 13 representing represent VBG cord-005646-xhx9pzhj 2851 14 acute acute JJ cord-005646-xhx9pzhj 2851 15 severity severity NN cord-005646-xhx9pzhj 2851 16 of of IN cord-005646-xhx9pzhj 2851 17 illness illness NN cord-005646-xhx9pzhj 2851 18 , , , cord-005646-xhx9pzhj 2851 19 are be VBP cord-005646-xhx9pzhj 2851 20 important important JJ cord-005646-xhx9pzhj 2851 21 prognostic prognostic JJ cord-005646-xhx9pzhj 2851 22 indicators indicator NNS cord-005646-xhx9pzhj 2851 23 for for IN cord-005646-xhx9pzhj 2851 24 survival survival NN cord-005646-xhx9pzhj 2851 25 and and CC cord-005646-xhx9pzhj 2851 26 health health NN cord-005646-xhx9pzhj 2851 27 status status NN cord-005646-xhx9pzhj 2851 28 of of IN cord-005646-xhx9pzhj 2851 29 children child NNS cord-005646-xhx9pzhj 2851 30 after after IN cord-005646-xhx9pzhj 2851 31 submersion submersion NN cord-005646-xhx9pzhj 2851 32 . . . cord-005646-xhx9pzhj 2852 1 There there EX cord-005646-xhx9pzhj 2852 2 were be VBD cord-005646-xhx9pzhj 2853 1 59 59 CD cord-005646-xhx9pzhj 2853 2 ( ( -LRB- cord-005646-xhx9pzhj 2853 3 91 91 CD cord-005646-xhx9pzhj 2853 4 % % NN cord-005646-xhx9pzhj 2853 5 ) ) -RRB- cord-005646-xhx9pzhj 2853 6 bronchoscopies bronchoscopie NNS cord-005646-xhx9pzhj 2853 7 , , , cord-005646-xhx9pzhj 2853 8 and and CC cord-005646-xhx9pzhj 2853 9 6 6 CD cord-005646-xhx9pzhj 2853 10 ( ( -LRB- cord-005646-xhx9pzhj 2853 11 9 9 CD cord-005646-xhx9pzhj 2853 12 % % NN cord-005646-xhx9pzhj 2853 13 ) ) -RRB- cord-005646-xhx9pzhj 2853 14 were be VBD cord-005646-xhx9pzhj 2853 15 oesophagoscopies oesophagoscopie NNS cord-005646-xhx9pzhj 2853 16 . . . cord-005646-xhx9pzhj 2854 1 The the DT cord-005646-xhx9pzhj 2854 2 average average JJ cord-005646-xhx9pzhj 2854 3 age age NN cord-005646-xhx9pzhj 2854 4 was be VBD cord-005646-xhx9pzhj 2854 5 2,8 2,8 CD cord-005646-xhx9pzhj 2854 6 years year NNS cord-005646-xhx9pzhj 2854 7 for for IN cord-005646-xhx9pzhj 2854 8 bronchoscopies bronchoscopie NNS cord-005646-xhx9pzhj 2854 9 , , , cord-005646-xhx9pzhj 2854 10 and and CC cord-005646-xhx9pzhj 2854 11 4 4 CD cord-005646-xhx9pzhj 2854 12 years year NNS cord-005646-xhx9pzhj 2854 13 for for IN cord-005646-xhx9pzhj 2854 14 oesophagoscopies oesophagoscopie NNS cord-005646-xhx9pzhj 2854 15 . . . cord-005646-xhx9pzhj 2855 1 The the DT cord-005646-xhx9pzhj 2855 2 outcome outcome NN cord-005646-xhx9pzhj 2855 3 of of IN cord-005646-xhx9pzhj 2855 4 the the DT cord-005646-xhx9pzhj 2855 5 patients patient NNS cord-005646-xhx9pzhj 2855 6 was be VBD cord-005646-xhx9pzhj 2855 7 good good JJ cord-005646-xhx9pzhj 2855 8 . . . cord-005646-xhx9pzhj 2856 1 No no DT cord-005646-xhx9pzhj 2856 2 complications complication NNS cord-005646-xhx9pzhj 2856 3 were be VBD cord-005646-xhx9pzhj 2856 4 observed observe VBN cord-005646-xhx9pzhj 2856 5 . . . cord-005646-xhx9pzhj 2857 1 Extraction extraction NN cord-005646-xhx9pzhj 2857 2 is be VBZ cord-005646-xhx9pzhj 2857 3 recomended recomende VBN cord-005646-xhx9pzhj 2857 4 in in IN cord-005646-xhx9pzhj 2857 5 every every DT cord-005646-xhx9pzhj 2857 6 symptomatic symptomatic JJ cord-005646-xhx9pzhj 2857 7 patient patient NN cord-005646-xhx9pzhj 2857 8 . . . cord-005646-xhx9pzhj 2858 1 Orphenadrine Orphenadrine NNP cord-005646-xhx9pzhj 2858 2 is be VBZ cord-005646-xhx9pzhj 2858 3 an an DT cord-005646-xhx9pzhj 2858 4 anticholinergic anticholinergic JJ cord-005646-xhx9pzhj 2858 5 drug drug NN cord-005646-xhx9pzhj 2858 6 mainly mainly RB cord-005646-xhx9pzhj 2858 7 used use VBN cord-005646-xhx9pzhj 2858 8 to to TO cord-005646-xhx9pzhj 2858 9 decrease decrease VB cord-005646-xhx9pzhj 2858 10 symptoms symptom NNS cord-005646-xhx9pzhj 2858 11 of of IN cord-005646-xhx9pzhj 2858 12 Parkinson Parkinson NNP cord-005646-xhx9pzhj 2858 13 disease disease NN cord-005646-xhx9pzhj 2858 14 . . . cord-005646-xhx9pzhj 2859 1 Orphenadrine Orphenadrine NNP cord-005646-xhx9pzhj 2859 2 has have VBZ cord-005646-xhx9pzhj 2859 3 a a DT cord-005646-xhx9pzhj 2859 4 peripheral peripheral JJ cord-005646-xhx9pzhj 2859 5 and and CC cord-005646-xhx9pzhj 2859 6 central central JJ cord-005646-xhx9pzhj 2859 7 effect effect NN cord-005646-xhx9pzhj 2859 8 and and CC cord-005646-xhx9pzhj 2859 9 overdose overdose NN cord-005646-xhx9pzhj 2859 10 can can MD cord-005646-xhx9pzhj 2859 11 result result VB cord-005646-xhx9pzhj 2859 12 in in IN cord-005646-xhx9pzhj 2859 13 athetoid athetoid JJ cord-005646-xhx9pzhj 2859 14 movements movement NNS cord-005646-xhx9pzhj 2859 15 , , , cord-005646-xhx9pzhj 2859 16 convulsions convulsion NNS cord-005646-xhx9pzhj 2859 17 , , , cord-005646-xhx9pzhj 2859 18 cyanosis cyanosis NN cord-005646-xhx9pzhj 2859 19 , , , cord-005646-xhx9pzhj 2859 20 coma coma NN cord-005646-xhx9pzhj 2859 21 , , , cord-005646-xhx9pzhj 2859 22 arrhythmias arrhythmias RB cord-005646-xhx9pzhj 2859 23 , , , cord-005646-xhx9pzhj 2859 24 shock shock NN cord-005646-xhx9pzhj 2859 25 and and CC cord-005646-xhx9pzhj 2859 26 cardiac cardiac JJ cord-005646-xhx9pzhj 2859 27 arrest arrest NN cord-005646-xhx9pzhj 2859 28 . . . cord-005646-xhx9pzhj 2860 1 Physostigmine Physostigmine NNP cord-005646-xhx9pzhj 2860 2 is be VBZ cord-005646-xhx9pzhj 2860 3 a a DT cord-005646-xhx9pzhj 2860 4 specific specific JJ cord-005646-xhx9pzhj 2860 5 antagonist antagonist NN cord-005646-xhx9pzhj 2860 6 of of IN cord-005646-xhx9pzhj 2860 7 the the DT cord-005646-xhx9pzhj 2860 8 peripheral peripheral JJ cord-005646-xhx9pzhj 2860 9 and and CC cord-005646-xhx9pzhj 2860 10 central central JJ cord-005646-xhx9pzhj 2860 11 effects effect NNS cord-005646-xhx9pzhj 2860 12 and and CC cord-005646-xhx9pzhj 2860 13 can can MD cord-005646-xhx9pzhj 2860 14 be be VB cord-005646-xhx9pzhj 2860 15 a a DT cord-005646-xhx9pzhj 2860 16 useful useful JJ cord-005646-xhx9pzhj 2860 17 antidote antidote NN cord-005646-xhx9pzhj 2860 18 . . . cord-005646-xhx9pzhj 2861 1 We -PRON- PRP cord-005646-xhx9pzhj 2861 2 report report VBP cord-005646-xhx9pzhj 2861 3 the the DT cord-005646-xhx9pzhj 2861 4 case case NN cord-005646-xhx9pzhj 2861 5 of of IN cord-005646-xhx9pzhj 2861 6 a a DT cord-005646-xhx9pzhj 2861 7 two two CD cord-005646-xhx9pzhj 2861 8 and and CC cord-005646-xhx9pzhj 2861 9 a a DT cord-005646-xhx9pzhj 2861 10 half half JJ cord-005646-xhx9pzhj 2861 11 year year NN cord-005646-xhx9pzhj 2861 12 old old JJ cord-005646-xhx9pzhj 2861 13 female female NN cord-005646-xhx9pzhj 2861 14 who who WP cord-005646-xhx9pzhj 2861 15 was be VBD cord-005646-xhx9pzhj 2861 16 transfered transfer VBN cord-005646-xhx9pzhj 2861 17 to to IN cord-005646-xhx9pzhj 2861 18 our -PRON- PRP$ cord-005646-xhx9pzhj 2861 19 ICU ICU NNP cord-005646-xhx9pzhj 2861 20 for for IN cord-005646-xhx9pzhj 2861 21 general general JJ cord-005646-xhx9pzhj 2861 22 convulsions convulsion NNS cord-005646-xhx9pzhj 2861 23 . . . cord-005646-xhx9pzhj 2862 1 The the DT cord-005646-xhx9pzhj 2862 2 little little JJ cord-005646-xhx9pzhj 2862 3 girl girl NN cord-005646-xhx9pzhj 2862 4 had have VBD cord-005646-xhx9pzhj 2862 5 , , , cord-005646-xhx9pzhj 2862 6 three three CD cord-005646-xhx9pzhj 2862 7 hours hour NNS cord-005646-xhx9pzhj 2862 8 before before IN cord-005646-xhx9pzhj 2862 9 admission admission NN cord-005646-xhx9pzhj 2862 10 , , , cord-005646-xhx9pzhj 2862 11 accidently accidently RB cord-005646-xhx9pzhj 2862 12 ingested ingest VBD cord-005646-xhx9pzhj 2862 13 400rag 400rag CD cord-005646-xhx9pzhj 2862 14 of of IN cord-005646-xhx9pzhj 2862 15 orphenadrinehydrochlodde orphenadrinehydrochlodde NNP cord-005646-xhx9pzhj 2863 1 ( ( -LRB- cord-005646-xhx9pzhj 2863 2 Disipal Disipal NNP cord-005646-xhx9pzhj 2863 3 ® ® NNP cord-005646-xhx9pzhj 2863 4 ) ) -RRB- cord-005646-xhx9pzhj 2863 5 , , , cord-005646-xhx9pzhj 2863 6 which which WDT cord-005646-xhx9pzhj 2863 7 was be VBD cord-005646-xhx9pzhj 2863 8 her -PRON- PRP$ cord-005646-xhx9pzhj 2863 9 grandmothers grandmother NNS cord-005646-xhx9pzhj 2863 10 anti anti JJ cord-005646-xhx9pzhj 2863 11 - - JJ cord-005646-xhx9pzhj 2863 12 parkinson parkinson JJ cord-005646-xhx9pzhj 2863 13 medication medication NN cord-005646-xhx9pzhj 2863 14 . . . cord-005646-xhx9pzhj 2864 1 Three three CD cord-005646-xhx9pzhj 2864 2 hours hour NNS cord-005646-xhx9pzhj 2864 3 after after IN cord-005646-xhx9pzhj 2864 4 ingestion ingestion NN cord-005646-xhx9pzhj 2864 5 she -PRON- PRP cord-005646-xhx9pzhj 2864 6 presented present VBD cord-005646-xhx9pzhj 2864 7 neurological neurological JJ cord-005646-xhx9pzhj 2864 8 signs sign NNS cord-005646-xhx9pzhj 2864 9 : : : cord-005646-xhx9pzhj 2864 10 confusion confusion NN cord-005646-xhx9pzhj 2864 11 , , , cord-005646-xhx9pzhj 2864 12 unstable unstable JJ cord-005646-xhx9pzhj 2864 13 walking walking NN cord-005646-xhx9pzhj 2864 14 , , , cord-005646-xhx9pzhj 2864 15 and and CC cord-005646-xhx9pzhj 2864 16 periods period NNS cord-005646-xhx9pzhj 2864 17 of of IN cord-005646-xhx9pzhj 2864 18 aggression aggression NN cord-005646-xhx9pzhj 2864 19 . . . cord-005646-xhx9pzhj 2865 1 Generalized generalized JJ cord-005646-xhx9pzhj 2865 2 tonic tonic JJ cord-005646-xhx9pzhj 2865 3 - - HYPH cord-005646-xhx9pzhj 2865 4 clonic clonic JJ cord-005646-xhx9pzhj 2865 5 seizures seizure NNS cord-005646-xhx9pzhj 2865 6 appeared appear VBD cord-005646-xhx9pzhj 2865 7 who who WP cord-005646-xhx9pzhj 2865 8 were be VBD cord-005646-xhx9pzhj 2865 9 rebel rebel JJ cord-005646-xhx9pzhj 2865 10 to to IN cord-005646-xhx9pzhj 2865 11 administration administration NN cord-005646-xhx9pzhj 2865 12 of of IN cord-005646-xhx9pzhj 2865 13 multiple multiple NNP cord-005646-xhx9pzhj 2865 14 anti anti NNP cord-005646-xhx9pzhj 2865 15 epileptica epileptica NN cord-005646-xhx9pzhj 2865 16 but but CC cord-005646-xhx9pzhj 2865 17 ceased cease VBD cord-005646-xhx9pzhj 2865 18 after after IN cord-005646-xhx9pzhj 2865 19 IV IV NNP cord-005646-xhx9pzhj 2865 20 administration administration NN cord-005646-xhx9pzhj 2865 21 of of IN cord-005646-xhx9pzhj 2865 22 diazepam diazepam NNP cord-005646-xhx9pzhj 2865 23 and and CC cord-005646-xhx9pzhj 2865 24 endotracheal endotracheal JJ cord-005646-xhx9pzhj 2865 25 intubation intubation NN cord-005646-xhx9pzhj 2865 26 and and CC cord-005646-xhx9pzhj 2865 27 ventilation ventilation NN cord-005646-xhx9pzhj 2865 28 . . . cord-005646-xhx9pzhj 2866 1 An an DT cord-005646-xhx9pzhj 2866 2 episode episode NN cord-005646-xhx9pzhj 2866 3 of of IN cord-005646-xhx9pzhj 2866 4 ventdcular ventdcular NNP cord-005646-xhx9pzhj 2866 5 tachycardia tachycardia NN cord-005646-xhx9pzhj 2866 6 responded respond VBD cord-005646-xhx9pzhj 2866 7 well well RB cord-005646-xhx9pzhj 2866 8 to to IN cord-005646-xhx9pzhj 2866 9 the the DT cord-005646-xhx9pzhj 2866 10 IV IV NNP cord-005646-xhx9pzhj 2866 11 administration administration NN cord-005646-xhx9pzhj 2866 12 of of IN cord-005646-xhx9pzhj 2866 13 tidocaine tidocaine NNP cord-005646-xhx9pzhj 2866 14 . . . cord-005646-xhx9pzhj 2867 1 The the DT cord-005646-xhx9pzhj 2867 2 levels level NNS cord-005646-xhx9pzhj 2867 3 of of IN cord-005646-xhx9pzhj 2867 4 orphenaddne orphenaddne NNP cord-005646-xhx9pzhj 2867 5 in in IN cord-005646-xhx9pzhj 2867 6 the the DT cord-005646-xhx9pzhj 2867 7 serum serum NN cord-005646-xhx9pzhj 2867 8 were be VBD cord-005646-xhx9pzhj 2867 9 high high JJ cord-005646-xhx9pzhj 2867 10 at at IN cord-005646-xhx9pzhj 2867 11 admission admission NN cord-005646-xhx9pzhj 2867 12 ( ( -LRB- cord-005646-xhx9pzhj 2867 13 3550pg 3550pg NNP cord-005646-xhx9pzhj 2867 14 / / SYM cord-005646-xhx9pzhj 2867 15 L L NNP cord-005646-xhx9pzhj 2867 16 ) ) -RRB- cord-005646-xhx9pzhj 2867 17 and and CC cord-005646-xhx9pzhj 2867 18 were be VBD cord-005646-xhx9pzhj 2867 19 present present JJ cord-005646-xhx9pzhj 2867 20 in in IN cord-005646-xhx9pzhj 2867 21 the the DT cord-005646-xhx9pzhj 2867 22 blood blood NN cord-005646-xhx9pzhj 2867 23 up up IN cord-005646-xhx9pzhj 2867 24 to to TO cord-005646-xhx9pzhj 2867 25 96 96 CD cord-005646-xhx9pzhj 2867 26 hours hour NNS cord-005646-xhx9pzhj 2867 27 after after IN cord-005646-xhx9pzhj 2867 28 ingestion ingestion NN cord-005646-xhx9pzhj 2867 29 . . . cord-005646-xhx9pzhj 2868 1 High high JJ cord-005646-xhx9pzhj 2868 2 serum serum NN cord-005646-xhx9pzhj 2868 3 levels level NNS cord-005646-xhx9pzhj 2868 4 are be VBP cord-005646-xhx9pzhj 2868 5 , , , cord-005646-xhx9pzhj 2868 6 in in IN cord-005646-xhx9pzhj 2868 7 the the DT cord-005646-xhx9pzhj 2868 8 literature literature NN cord-005646-xhx9pzhj 2868 9 , , , cord-005646-xhx9pzhj 2868 10 associated associate VBN cord-005646-xhx9pzhj 2868 11 to to IN cord-005646-xhx9pzhj 2868 12 a a DT cord-005646-xhx9pzhj 2868 13 high high JJ cord-005646-xhx9pzhj 2868 14 mortality mortality NN cord-005646-xhx9pzhj 2868 15 rate rate NN cord-005646-xhx9pzhj 2868 16 . . . cord-005646-xhx9pzhj 2869 1 Physostigmine Physostigmine NNP cord-005646-xhx9pzhj 2869 2 was be VBD cord-005646-xhx9pzhj 2869 3 administered administer VBN cord-005646-xhx9pzhj 2869 4 three three CD cord-005646-xhx9pzhj 2869 5 times time NNS cord-005646-xhx9pzhj 2869 6 at at IN cord-005646-xhx9pzhj 2869 7 a a DT cord-005646-xhx9pzhj 2869 8 0.02mg 0.02mg CD cord-005646-xhx9pzhj 2869 9 / / SYM cord-005646-xhx9pzhj 2869 10 kg kg NNS cord-005646-xhx9pzhj 2869 11 dose dose NN cord-005646-xhx9pzhj 2869 12 in in IN cord-005646-xhx9pzhj 2869 13 the the DT cord-005646-xhx9pzhj 2869 14 first first JJ cord-005646-xhx9pzhj 2869 15 24 24 CD cord-005646-xhx9pzhj 2869 16 hours hour NNS cord-005646-xhx9pzhj 2869 17 . . . cord-005646-xhx9pzhj 2870 1 We -PRON- PRP cord-005646-xhx9pzhj 2870 2 decribe decribe VBP cord-005646-xhx9pzhj 2870 3 the the DT cord-005646-xhx9pzhj 2870 4 noted note VBN cord-005646-xhx9pzhj 2870 5 effects effect NNS cord-005646-xhx9pzhj 2870 6 of of IN cord-005646-xhx9pzhj 2870 7 physostigmine physostigmine NN cord-005646-xhx9pzhj 2870 8 on on IN cord-005646-xhx9pzhj 2870 9 the the DT cord-005646-xhx9pzhj 2870 10 different different JJ cord-005646-xhx9pzhj 2870 11 symptoms symptom NNS cord-005646-xhx9pzhj 2870 12 . . . cord-005646-xhx9pzhj 2871 1 The the DT cord-005646-xhx9pzhj 2871 2 patient patient NN cord-005646-xhx9pzhj 2871 3 survived survive VBD cord-005646-xhx9pzhj 2871 4 and and CC cord-005646-xhx9pzhj 2871 5 could could MD cord-005646-xhx9pzhj 2871 6 leave leave VB cord-005646-xhx9pzhj 2871 7 the the DT cord-005646-xhx9pzhj 2871 8 ICU ICU NNP cord-005646-xhx9pzhj 2871 9 after after IN cord-005646-xhx9pzhj 2871 10 one one CD cord-005646-xhx9pzhj 2871 11 week week NN cord-005646-xhx9pzhj 2871 12 . . . cord-005646-xhx9pzhj 2872 1 In in IN cord-005646-xhx9pzhj 2872 2 conclusion conclusion NN cord-005646-xhx9pzhj 2872 3 : : : cord-005646-xhx9pzhj 2872 4 orphenadrine orphenadrine NNP cord-005646-xhx9pzhj 2872 5 poisoning poisoning NN cord-005646-xhx9pzhj 2872 6 is be VBZ cord-005646-xhx9pzhj 2872 7 a a DT cord-005646-xhx9pzhj 2872 8 very very RB cord-005646-xhx9pzhj 2872 9 complicated complicated JJ cord-005646-xhx9pzhj 2872 10 medical medical JJ cord-005646-xhx9pzhj 2872 11 problem problem NN cord-005646-xhx9pzhj 2872 12 associated associate VBN cord-005646-xhx9pzhj 2872 13 with with IN cord-005646-xhx9pzhj 2872 14 high high JJ cord-005646-xhx9pzhj 2872 15 mortality mortality NN cord-005646-xhx9pzhj 2872 16 . . . cord-005646-xhx9pzhj 2873 1 In in IN cord-005646-xhx9pzhj 2873 2 severe severe JJ cord-005646-xhx9pzhj 2873 3 intoxication intoxication NN cord-005646-xhx9pzhj 2873 4 , , , cord-005646-xhx9pzhj 2873 5 the the DT cord-005646-xhx9pzhj 2873 6 benefit benefit NN cord-005646-xhx9pzhj 2873 7 of of IN cord-005646-xhx9pzhj 2873 8 physostigmine physostigmine NN cord-005646-xhx9pzhj 2873 9 more more RBR cord-005646-xhx9pzhj 2873 10 than than IN cord-005646-xhx9pzhj 2873 11 counterbalances counterbalance VBZ cord-005646-xhx9pzhj 2873 12 its -PRON- PRP$ cord-005646-xhx9pzhj 2873 13 side side NN cord-005646-xhx9pzhj 2873 14 effects effect NNS cord-005646-xhx9pzhj 2873 15 . . . cord-005646-xhx9pzhj 2874 1 Objective objective NN cord-005646-xhx9pzhj 2874 2 : : : cord-005646-xhx9pzhj 2875 1 To to TO cord-005646-xhx9pzhj 2875 2 define define VB cord-005646-xhx9pzhj 2875 3 the the DT cord-005646-xhx9pzhj 2875 4 optimal optimal JJ cord-005646-xhx9pzhj 2875 5 volume volume NN cord-005646-xhx9pzhj 2875 6 of of IN cord-005646-xhx9pzhj 2875 7 dilution dilution NN cord-005646-xhx9pzhj 2875 8 for for IN cord-005646-xhx9pzhj 2875 9 endotracheal endotracheal NN cord-005646-xhx9pzhj 2875 10 ( ( -LRB- cord-005646-xhx9pzhj 2875 11 ET ET NNP cord-005646-xhx9pzhj 2875 12 ) ) -RRB- cord-005646-xhx9pzhj 2875 13 administration administration NN cord-005646-xhx9pzhj 2875 14 of of IN cord-005646-xhx9pzhj 2875 15 epinephrine epinephrine NNP cord-005646-xhx9pzhj 2876 1 ( ( -LRB- cord-005646-xhx9pzhj 2876 2 EPI EPI NNP cord-005646-xhx9pzhj 2876 3 ) ) -RRB- cord-005646-xhx9pzhj 2876 4 Design design NN cord-005646-xhx9pzhj 2876 5 : : : cord-005646-xhx9pzhj 2876 6 Prospective prospective JJ cord-005646-xhx9pzhj 2876 7 , , , cord-005646-xhx9pzhj 2876 8 randomized randomized JJ cord-005646-xhx9pzhj 2876 9 , , , cord-005646-xhx9pzhj 2876 10 laboratory laboratory NN cord-005646-xhx9pzhj 2876 11 comparison comparison NN cord-005646-xhx9pzhj 2876 12 of of IN cord-005646-xhx9pzhj 2876 13 four four CD cord-005646-xhx9pzhj 2876 14 different different JJ cord-005646-xhx9pzhj 2876 15 volumes volume NNS cord-005646-xhx9pzhj 2876 16 of of IN cord-005646-xhx9pzhj 2876 17 dilution dilution NN cord-005646-xhx9pzhj 2876 18 of of IN cord-005646-xhx9pzhj 2876 19 endotracheal endotracheal NN cord-005646-xhx9pzhj 2876 20 epinephrine epinephrine NN cord-005646-xhx9pzhj 2876 21 ( ( -LRB- cord-005646-xhx9pzhj 2876 22 1.2 1.2 CD cord-005646-xhx9pzhj 2876 23 , , , cord-005646-xhx9pzhj 2876 24 5 5 CD cord-005646-xhx9pzhj 2876 25 , , , cord-005646-xhx9pzhj 2876 26 and and CC cord-005646-xhx9pzhj 2876 27 10 10 CD cord-005646-xhx9pzhj 2876 28 ml ml NNS cord-005646-xhx9pzhj 2876 29 of of IN cord-005646-xhx9pzhj 2876 30 saline saline NN cord-005646-xhx9pzhj 2876 31 ) ) -RRB- cord-005646-xhx9pzhj 2876 32 Setting set VBG cord-005646-xhx9pzhj 2876 33 Large large JJ cord-005646-xhx9pzhj 2876 34 animal animal NN cord-005646-xhx9pzhj 2876 35 research research NN cord-005646-xhx9pzhj 2876 36 facility facility NN cord-005646-xhx9pzhj 2877 1 ofa ofa NNP cord-005646-xhx9pzhj 2877 2 universi~ universi~ NNP cord-005646-xhx9pzhj 2877 3 medical medical JJ cord-005646-xhx9pzhj 2877 4 center center NN cord-005646-xhx9pzhj 2877 5 Subjects subject NNS cord-005646-xhx9pzhj 2877 6 and and CC cord-005646-xhx9pzhj 2877 7 interventions intervention NNS cord-005646-xhx9pzhj 2877 8 : : : cord-005646-xhx9pzhj 2877 9 Epinephrine epinephrine NN cord-005646-xhx9pzhj 2877 10 ( ( -LRB- cord-005646-xhx9pzhj 2877 11 0.02 0.02 CD cord-005646-xhx9pzhj 2877 12 mg mg NNP cord-005646-xhx9pzhj 2877 13 / / SYM cord-005646-xhx9pzhj 2877 14 kg kg NNP cord-005646-xhx9pzhj 2877 15 ) ) -RRB- cord-005646-xhx9pzhj 2877 16 diluted dilute VBD cord-005646-xhx9pzhj 2877 17 with with IN cord-005646-xhx9pzhj 2877 18 four four CD cord-005646-xhx9pzhj 2877 19 different different JJ cord-005646-xhx9pzhj 2877 20 volumes volume NNS cord-005646-xhx9pzhj 2877 21 ( ( -LRB- cord-005646-xhx9pzhj 2877 22 1 1 CD cord-005646-xhx9pzhj 2877 23 , , , cord-005646-xhx9pzhj 2877 24 2.5 2.5 CD cord-005646-xhx9pzhj 2877 25 . . . cord-005646-xhx9pzhj 2878 1 and and CC cord-005646-xhx9pzhj 2878 2 I -PRON- PRP cord-005646-xhx9pzhj 2878 3 0 0 CD cord-005646-xhx9pzhj 2878 4 rot rot VB cord-005646-xhx9pzhj 2878 5 ) ) -RRB- cord-005646-xhx9pzhj 2878 6 of of IN cord-005646-xhx9pzhj 2878 7 normal normal JJ cord-005646-xhx9pzhj 2878 8 saline saline NN cord-005646-xhx9pzhj 2878 9 was be VBD cord-005646-xhx9pzhj 2878 10 injected inject VBN cord-005646-xhx9pzhj 2878 11 into into IN cord-005646-xhx9pzhj 2878 12 the the DT cord-005646-xhx9pzhj 2878 13 ET ET NNP cord-005646-xhx9pzhj 2878 14 tube tube NN cord-005646-xhx9pzhj 2878 15 of of IN cord-005646-xhx9pzhj 2878 16 five five CD cord-005646-xhx9pzhj 2878 17 anesthehzed anesthehze VBN cord-005646-xhx9pzhj 2878 18 dogs dog NNS cord-005646-xhx9pzhj 2878 19 . . . cord-005646-xhx9pzhj 2879 1 Each each DT cord-005646-xhx9pzhj 2879 2 dog dog NN cord-005646-xhx9pzhj 2879 3 served serve VBD cord-005646-xhx9pzhj 2879 4 as as IN cord-005646-xhx9pzhj 2879 5 its -PRON- PRP$ cord-005646-xhx9pzhj 2879 6 own own JJ cord-005646-xhx9pzhj 2879 7 control control NN cord-005646-xhx9pzhj 2879 8 and and CC cord-005646-xhx9pzhj 2879 9 received receive VBD cord-005646-xhx9pzhj 2879 10 all all DT cord-005646-xhx9pzhj 2879 11 four four CD cord-005646-xhx9pzhj 2879 12 volumes volume NNS cord-005646-xhx9pzhj 2879 13 in in IN cord-005646-xhx9pzhj 2879 14 different different JJ cord-005646-xhx9pzhj 2879 15 sequences sequence NNS cord-005646-xhx9pzhj 2879 16 at at IN cord-005646-xhx9pzhj 2879 17 Ieast Ieast NNP cord-005646-xhx9pzhj 2879 18 one one CD cord-005646-xhx9pzhj 2879 19 week week NN cord-005646-xhx9pzhj 2879 20 apart apart RB cord-005646-xhx9pzhj 2879 21 . . . cord-005646-xhx9pzhj 2880 1 Arterial arterial JJ cord-005646-xhx9pzhj 2880 2 blood blood NN cord-005646-xhx9pzhj 2880 3 samples sample NNS cord-005646-xhx9pzhj 2880 4 for for IN cord-005646-xhx9pzhj 2880 5 plasma plasma NN cord-005646-xhx9pzhj 2880 6 epinephrine epinephrine NN cord-005646-xhx9pzhj 2880 7 concentration concentration NN cord-005646-xhx9pzhj 2880 8 and and CC cord-005646-xhx9pzhj 2880 9 blood blood NN cord-005646-xhx9pzhj 2880 10 gases.were gases.were RB cord-005646-xhx9pzhj 2880 11 collected collect VBN cord-005646-xhx9pzhj 2880 12 before before RB cord-005646-xhx9pzhj 2880 13 and and CC cord-005646-xhx9pzhj 2880 14 0.25 0.25 CD cord-005646-xhx9pzhj 2880 15 , , , cord-005646-xhx9pzhj 2880 16 0.5 0.5 CD cord-005646-xhx9pzhj 2880 17 . . . cord-005646-xhx9pzhj 2881 1 0.75 0.75 CD cord-005646-xhx9pzhj 2881 2 _ _ NNP cord-005646-xhx9pzhj 2881 3 1.2.3 1.2.3 NNP cord-005646-xhx9pzhj 2881 4 , , , cord-005646-xhx9pzhj 2881 5 4 4 CD cord-005646-xhx9pzhj 2881 6 . . CD cord-005646-xhx9pzhj 2881 7 5 5 CD cord-005646-xhx9pzhj 2881 8 . . . cord-005646-xhx9pzhj 2881 9 10 10 CD cord-005646-xhx9pzhj 2881 10 , , , cord-005646-xhx9pzhj 2881 11 15.20 15.20 CD cord-005646-xhx9pzhj 2881 12 , , , cord-005646-xhx9pzhj 2881 13 25.30 25.30 CD cord-005646-xhx9pzhj 2881 14 , , , cord-005646-xhx9pzhj 2881 15 and and CC cord-005646-xhx9pzhj 2881 16 60 60 CD cord-005646-xhx9pzhj 2881 17 minutes minute NNS cord-005646-xhx9pzhj 2881 18 after after IN cord-005646-xhx9pzhj 2881 19 drug drug NN cord-005646-xhx9pzhj 2881 20 administration administration NN cord-005646-xhx9pzhj 2881 21 . . . cord-005646-xhx9pzhj 2882 1 Heart heart NN cord-005646-xhx9pzhj 2882 2 rate rate NN cord-005646-xhx9pzhj 2882 3 and and CC cord-005646-xhx9pzhj 2882 4 arterial arterial JJ cord-005646-xhx9pzhj 2882 5 blood blood NN cord-005646-xhx9pzhj 2882 6 pressure pressure NN cord-005646-xhx9pzhj 2882 7 were be VBD cord-005646-xhx9pzhj 2882 8 continuously continuously RB cord-005646-xhx9pzhj 2882 9 monitored monitor VBN cord-005646-xhx9pzhj 2882 10 . . . cord-005646-xhx9pzhj 2883 1 Measurements measurement NNS cord-005646-xhx9pzhj 2883 2 and and CC cord-005646-xhx9pzhj 2883 3 Main main JJ cord-005646-xhx9pzhj 2883 4 Results result NNS cord-005646-xhx9pzhj 2883 5 : : : cord-005646-xhx9pzhj 2883 6 Higher high JJR cord-005646-xhx9pzhj 2883 7 volumes volume NNS cord-005646-xhx9pzhj 2883 8 of of IN cord-005646-xhx9pzhj 2883 9 diluent diluent NN cord-005646-xhx9pzhj 2883 10 ( ( -LRB- cord-005646-xhx9pzhj 2883 11 5 5 CD cord-005646-xhx9pzhj 2883 12 and and CC cord-005646-xhx9pzhj 2883 13 I0 I0 NNP cord-005646-xhx9pzhj 2883 14 ml ml NNP cord-005646-xhx9pzhj 2883 15 ) ) -RRB- cord-005646-xhx9pzhj 2883 16 caused cause VBD cord-005646-xhx9pzhj 2883 17 a a DT cord-005646-xhx9pzhj 2883 18 significant significant JJ cord-005646-xhx9pzhj 2883 19 decrease decrease NN cord-005646-xhx9pzhj 2883 20 of of IN cord-005646-xhx9pzhj 2883 21 PaO2 PaO2 NNS cord-005646-xhx9pzhj 2883 22 , , , cord-005646-xhx9pzhj 2883 23 from from IN cord-005646-xhx9pzhj 2883 24 147:!:8 147:!:8 CD cord-005646-xhx9pzhj 2883 25 tort tort NN cord-005646-xhx9pzhj 2883 26 to to IN cord-005646-xhx9pzhj 2883 27 106±I0 106±i0 CD cord-005646-xhx9pzhj 2883 28 torr torr NNS cord-005646-xhx9pzhj 2883 29 , , , cord-005646-xhx9pzhj 2883 30 compared compare VBN cord-005646-xhx9pzhj 2883 31 to to IN cord-005646-xhx9pzhj 2883 32 the the DT cord-005646-xhx9pzhj 2883 33 tower tower NN cord-005646-xhx9pzhj 2883 34 volumes volume NNS cord-005646-xhx9pzhj 2883 35 of of IN cord-005646-xhx9pzhj 2883 36 diluent diluent NN cord-005646-xhx9pzhj 2883 37 ( ( -LRB- cord-005646-xhx9pzhj 2883 38 1 1 CD cord-005646-xhx9pzhj 2883 39 and and CC cord-005646-xhx9pzhj 2883 40 2 2 CD cord-005646-xhx9pzhj 2883 41 ml ml NNS cord-005646-xhx9pzhj 2883 42 ) ) -RRB- cord-005646-xhx9pzhj 2883 43 , , , cord-005646-xhx9pzhj 2883 44 from from IN cord-005646-xhx9pzhj 2883 45 136±10 136±10 CD cord-005646-xhx9pzhj 2883 46 torr torr NNP cord-005646-xhx9pzhj 2883 47 tu135+_7 tu135+_7 NNP cord-005646-xhx9pzhj 2883 48 torr torr NNP cord-005646-xhx9pzhj 2883 49 ( ( -LRB- cord-005646-xhx9pzhj 2883 50 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 2883 51 ) ) -RRB- cord-005646-xhx9pzhj 2883 52 . . . cord-005646-xhx9pzhj 2884 1 These these DT cord-005646-xhx9pzhj 2884 2 effects effect NNS cord-005646-xhx9pzhj 2884 3 persisted persist VBD cord-005646-xhx9pzhj 2884 4 for for IN cord-005646-xhx9pzhj 2884 5 over over IN cord-005646-xhx9pzhj 2884 6 30 30 CD cord-005646-xhx9pzhj 2884 7 minutes minute NNS cord-005646-xhx9pzhj 2884 8 . . . cord-005646-xhx9pzhj 2885 1 Mean mean JJ cord-005646-xhx9pzhj 2885 2 plasma plasma NN cord-005646-xhx9pzhj 2885 3 epinephrine epinephrine NN cord-005646-xhx9pzhj 2885 4 concentrations concentration NNS cord-005646-xhx9pzhj 2885 5 significantly significantly RB cord-005646-xhx9pzhj 2885 6 increased increase VBD cord-005646-xhx9pzhj 2885 7 within within IN cord-005646-xhx9pzhj 2885 8 15 15 CD cord-005646-xhx9pzhj 2885 9 seconds second NNS cord-005646-xhx9pzhj 2885 10 following follow VBG cord-005646-xhx9pzhj 2885 11 administration administration NN cord-005646-xhx9pzhj 2885 12 for for IN cord-005646-xhx9pzhj 2885 13 all all PDT cord-005646-xhx9pzhj 2885 14 the the DT cord-005646-xhx9pzhj 2885 15 volumes volume NNS cord-005646-xhx9pzhj 2885 16 of of IN cord-005646-xhx9pzhj 2885 17 diluent diluent NN cord-005646-xhx9pzhj 2885 18 . . . cord-005646-xhx9pzhj 2886 1 Mean mean JJ cord-005646-xhx9pzhj 2886 2 plasma plasma NN cord-005646-xhx9pzhj 2886 3 epinephrine epinephrine NN cord-005646-xhx9pzhj 2886 4 concentrations concentration NNS cord-005646-xhx9pzhj 2886 5 , , , cord-005646-xhx9pzhj 2886 6 maximal maximal JJ cord-005646-xhx9pzhj 2886 7 epinephrine epinephrine NN cord-005646-xhx9pzhj 2886 8 concentration concentration NN cord-005646-xhx9pzhj 2886 9 ( ( -LRB- cord-005646-xhx9pzhj 2886 10 Cmax Cmax NNP cord-005646-xhx9pzhj 2886 11 ) ) -RRB- cord-005646-xhx9pzhj 2886 12 , , , cord-005646-xhx9pzhj 2886 13 and and CC cord-005646-xhx9pzhj 2886 14 the the DT cord-005646-xhx9pzhj 2886 15 coefficient coefficient NN cord-005646-xhx9pzhj 2886 16 of of IN cord-005646-xhx9pzhj 2886 17 absorption absorption NN cord-005646-xhx9pzhj 2886 18 ( ( -LRB- cord-005646-xhx9pzhj 2886 19 Ka Ka NNP cord-005646-xhx9pzhj 2886 20 ) ) -RRB- cord-005646-xhx9pzhj 2886 21 were be VBD cord-005646-xhx9pzhj 2886 22 higher high JJR cord-005646-xhx9pzhj 2886 23 in in IN cord-005646-xhx9pzhj 2886 24 the the DT cord-005646-xhx9pzhj 2886 25 5 5 CD cord-005646-xhx9pzhj 2886 26 ml ml NN cord-005646-xhx9pzhj 2886 27 and and CC cord-005646-xhx9pzhj 2886 28 10 10 CD cord-005646-xhx9pzhj 2886 29 ml ml NN cord-005646-xhx9pzhj 2886 30 groups group NNS cord-005646-xhx9pzhj 2886 31 . . . cord-005646-xhx9pzhj 2887 1 The the DT cord-005646-xhx9pzhj 2887 2 time time NN cord-005646-xhx9pzhj 2887 3 interval interval NN cord-005646-xhx9pzhj 2887 4 to to TO cord-005646-xhx9pzhj 2887 5 reach reach VB cord-005646-xhx9pzhj 2887 6 maximal maximal JJ cord-005646-xhx9pzhj 2887 7 concentration concentration NN cord-005646-xhx9pzhj 2887 8 ( ( -LRB- cord-005646-xhx9pzhj 2887 9 Tmax Tmax NNP cord-005646-xhx9pzhj 2887 10 ) ) -RRB- cord-005646-xhx9pzhj 2887 11 was be VBD cord-005646-xhx9pzhj 2887 12 shorter short JJR cord-005646-xhx9pzhj 2887 13 in in IN cord-005646-xhx9pzhj 2887 14 the the DT cord-005646-xhx9pzhj 2887 15 5 5 CD cord-005646-xhx9pzhj 2887 16 ml ml NN cord-005646-xhx9pzhj 2887 17 and and CC cord-005646-xhx9pzhj 2887 18 10 10 CD cord-005646-xhx9pzhj 2887 19 ml ml NN cord-005646-xhx9pzhj 2887 20 groups group NNS cord-005646-xhx9pzhj 2887 21 . . . cord-005646-xhx9pzhj 2888 1 Yet yet CC cord-005646-xhx9pzhj 2888 2 these these DT cord-005646-xhx9pzhj 2888 3 results result NNS cord-005646-xhx9pzhj 2888 4 were be VBD cord-005646-xhx9pzhj 2888 5 not not RB cord-005646-xhx9pzhj 2888 6 significantly significantly RB cord-005646-xhx9pzhj 2888 7 different different JJ cord-005646-xhx9pzhj 2888 8 . . . cord-005646-xhx9pzhj 2889 1 Heart heart NN cord-005646-xhx9pzhj 2889 2 rate rate NN cord-005646-xhx9pzhj 2889 3 . . . cord-005646-xhx9pzhj 2890 1 systolic systolic JJ cord-005646-xhx9pzhj 2890 2 and and CC cord-005646-xhx9pzhj 2890 3 diastolic diastolic JJ cord-005646-xhx9pzhj 2890 4 blood blood NN cord-005646-xhx9pzhj 2890 5 pressures pressure NNS cord-005646-xhx9pzhj 2890 6 did do VBD cord-005646-xhx9pzhj 2890 7 not not RB cord-005646-xhx9pzhj 2890 8 differ differ VB cord-005646-xhx9pzhj 2890 9 significantly significantly RB cord-005646-xhx9pzhj 2890 10 between between IN cord-005646-xhx9pzhj 2890 11 the the DT cord-005646-xhx9pzhj 2890 12 groups group NNS cord-005646-xhx9pzhj 2890 13 throughout throughout IN cord-005646-xhx9pzhj 2890 14 the the DT cord-005646-xhx9pzhj 2890 15 study study NN cord-005646-xhx9pzhj 2890 16 . . . cord-005646-xhx9pzhj 2891 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 2891 2 : : : cord-005646-xhx9pzhj 2892 1 Dilution dilution NN cord-005646-xhx9pzhj 2892 2 of of IN cord-005646-xhx9pzhj 2892 3 endotracheal endotracheal NN cord-005646-xhx9pzhj 2892 4 epinephrine epinephrine NN cord-005646-xhx9pzhj 2892 5 into into IN cord-005646-xhx9pzhj 2892 6 a a DT cord-005646-xhx9pzhj 2892 7 5 5 CD cord-005646-xhx9pzhj 2892 8 ml ml NN cord-005646-xhx9pzhj 2892 9 volume volume NN cord-005646-xhx9pzhj 2892 10 with with IN cord-005646-xhx9pzhj 2892 11 saline saline NN cord-005646-xhx9pzhj 2892 12 optimizes optimize VBZ cord-005646-xhx9pzhj 2892 13 drug drug NN cord-005646-xhx9pzhj 2892 14 uptake uptake NN cord-005646-xhx9pzhj 2892 15 and and CC cord-005646-xhx9pzhj 2892 16 delivery delivery NN cord-005646-xhx9pzhj 2892 17 , , , cord-005646-xhx9pzhj 2892 18 without without IN cord-005646-xhx9pzhj 2892 19 adversely adversely RB cord-005646-xhx9pzhj 2892 20 affecting affect VBG cord-005646-xhx9pzhj 2892 21 oxygenation oxygenation NN cord-005646-xhx9pzhj 2892 22 and and CC cord-005646-xhx9pzhj 2892 23 ventilation ventilation NN cord-005646-xhx9pzhj 2892 24 . . . cord-005646-xhx9pzhj 2893 1 The the DT cord-005646-xhx9pzhj 2893 2 aetiology aetiology NN cord-005646-xhx9pzhj 2893 3 and and CC cord-005646-xhx9pzhj 2893 4 outcome outcome NN cord-005646-xhx9pzhj 2893 5 of of IN cord-005646-xhx9pzhj 2893 6 paediatric paediatric JJ cord-005646-xhx9pzhj 2893 7 out out JJ cord-005646-xhx9pzhj 2893 8 - - HYPH cord-005646-xhx9pzhj 2893 9 of of IN cord-005646-xhx9pzhj 2893 10 - - HYPH cord-005646-xhx9pzhj 2893 11 hospital hospital NN cord-005646-xhx9pzhj 2893 12 cardiac cardiac JJ cord-005646-xhx9pzhj 2893 13 arrest arrest NN cord-005646-xhx9pzhj 2893 14 was be VBD cord-005646-xhx9pzhj 2893 15 studied study VBN cord-005646-xhx9pzhj 2893 16 during during IN cord-005646-xhx9pzhj 2893 17 a a DT cord-005646-xhx9pzhj 2893 18 10-year 10-year CD cord-005646-xhx9pzhj 2893 19 period period NN cord-005646-xhx9pzhj 2893 20 in in IN cord-005646-xhx9pzhj 2893 21 Southern Southern NNP cord-005646-xhx9pzhj 2893 22 Finland Finland NNP cord-005646-xhx9pzhj 2893 23 served serve VBD cord-005646-xhx9pzhj 2893 24 by by IN cord-005646-xhx9pzhj 2893 25 physician physician NN cord-005646-xhx9pzhj 2893 26 staffed staffed JJ cord-005646-xhx9pzhj 2893 27 emergency emergency NN cord-005646-xhx9pzhj 2893 28 care care NN cord-005646-xhx9pzhj 2893 29 units unit NNS cord-005646-xhx9pzhj 2893 30 . . . cord-005646-xhx9pzhj 2894 1 The the DT cord-005646-xhx9pzhj 2894 2 files file NNS cord-005646-xhx9pzhj 2894 3 of of IN cord-005646-xhx9pzhj 2894 4 100 100 CD cord-005646-xhx9pzhj 2894 5 prehospital prehospital JJ cord-005646-xhx9pzhj 2894 6 patients patient NNS cord-005646-xhx9pzhj 2894 7 less less JJR cord-005646-xhx9pzhj 2894 8 than than IN cord-005646-xhx9pzhj 2894 9 16 16 CD cord-005646-xhx9pzhj 2894 10 years year NNS cord-005646-xhx9pzhj 2894 11 old old JJ cord-005646-xhx9pzhj 2894 12 without without IN cord-005646-xhx9pzhj 2894 13 palpable palpable JJ cord-005646-xhx9pzhj 2894 14 pulse pulse NN cord-005646-xhx9pzhj 2894 15 and and CC cord-005646-xhx9pzhj 2894 16 spontaneous spontaneous JJ cord-005646-xhx9pzhj 2894 17 respiration respiration NN cord-005646-xhx9pzhj 2894 18 were be VBD cord-005646-xhx9pzhj 2894 19 analysed analyse VBN cord-005646-xhx9pzhj 2894 20 retrospectively retrospectively RB cord-005646-xhx9pzhj 2894 21 . . . cord-005646-xhx9pzhj 2895 1 Fifty fifty CD cord-005646-xhx9pzhj 2895 2 patients patient NNS cord-005646-xhx9pzhj 2895 3 were be VBD cord-005646-xhx9pzhj 2895 4 declared declare VBN cord-005646-xhx9pzhj 2895 5 dead dead JJ cord-005646-xhx9pzhj 2895 6 on on IN cord-005646-xhx9pzhj 2895 7 the the DT cord-005646-xhx9pzhj 2895 8 scene scene NN cord-005646-xhx9pzhj 2895 9 ( ( -LRB- cord-005646-xhx9pzhj 2895 10 DOS DOS NNP cord-005646-xhx9pzhj 2895 11 ) ) -RRB- cord-005646-xhx9pzhj 2895 12 and and CC cord-005646-xhx9pzhj 2895 13 resuscitation resuscitation NN cord-005646-xhx9pzhj 2895 14 ( ( -LRB- cord-005646-xhx9pzhj 2895 15 CPR CPR NNP cord-005646-xhx9pzhj 2895 16 ) ) -RRB- cord-005646-xhx9pzhj 2895 17 was be VBD cord-005646-xhx9pzhj 2895 18 initiated initiate VBN cord-005646-xhx9pzhj 2895 19 in in IN cord-005646-xhx9pzhj 2895 20 50 50 CD cord-005646-xhx9pzhj 2895 21 patients patient NNS cord-005646-xhx9pzhj 2895 22 . . . cord-005646-xhx9pzhj 2896 1 The the DT cord-005646-xhx9pzhj 2896 2 sudden sudden JJ cord-005646-xhx9pzhj 2896 3 infant infant NN cord-005646-xhx9pzhj 2896 4 death death NN cord-005646-xhx9pzhj 2896 5 syndrome syndrome NN cord-005646-xhx9pzhj 2896 6 was be VBD cord-005646-xhx9pzhj 2896 7 the the DT cord-005646-xhx9pzhj 2896 8 most most RBS cord-005646-xhx9pzhj 2896 9 common common JJ cord-005646-xhx9pzhj 2896 10 cause cause NN cord-005646-xhx9pzhj 2896 11 of of IN cord-005646-xhx9pzhj 2896 12 arrest arrest NN cord-005646-xhx9pzhj 2896 13 ( ( -LRB- cord-005646-xhx9pzhj 2896 14 68 68 CD cord-005646-xhx9pzhj 2896 15 % % NN cord-005646-xhx9pzhj 2896 16 ) ) -RRB- cord-005646-xhx9pzhj 2896 17 in in IN cord-005646-xhx9pzhj 2896 18 the the DT cord-005646-xhx9pzhj 2896 19 DOS DOS NNP cord-005646-xhx9pzhj 2896 20 patients patient NNS cord-005646-xhx9pzhj 2896 21 as as RB cord-005646-xhx9pzhj 2896 22 well well RB cord-005646-xhx9pzhj 2896 23 as as IN cord-005646-xhx9pzhj 2896 24 in in IN cord-005646-xhx9pzhj 2896 25 patients patient NNS cord-005646-xhx9pzhj 2896 26 receiving receive VBG cord-005646-xhx9pzhj 2896 27 CPR CPR NNP cord-005646-xhx9pzhj 2896 28 ( ( -LRB- cord-005646-xhx9pzhj 2896 29 36 36 CD cord-005646-xhx9pzhj 2896 30 % % NN cord-005646-xhx9pzhj 2896 31 ) ) -RRB- cord-005646-xhx9pzhj 2896 32 . . . cord-005646-xhx9pzhj 2897 1 Asystole asystole NN cord-005646-xhx9pzhj 2897 2 was be VBD cord-005646-xhx9pzhj 2897 3 the the DT cord-005646-xhx9pzhj 2897 4 initial initial JJ cord-005646-xhx9pzhj 2897 5 cardiac cardiac JJ cord-005646-xhx9pzhj 2897 6 rhythm rhythm NN cord-005646-xhx9pzhj 2897 7 in in IN cord-005646-xhx9pzhj 2897 8 70 70 CD cord-005646-xhx9pzhj 2897 9 % % NN cord-005646-xhx9pzhj 2897 10 of of IN cord-005646-xhx9pzhj 2897 11 the the DT cord-005646-xhx9pzhj 2897 12 patients patient NNS cord-005646-xhx9pzhj 2897 13 in in IN cord-005646-xhx9pzhj 2897 14 whom whom WP cord-005646-xhx9pzhj 2897 15 CPR CPR NNP cord-005646-xhx9pzhj 2897 16 was be VBD cord-005646-xhx9pzhj 2897 17 attempted attempt VBN cord-005646-xhx9pzhj 2897 18 . . . cord-005646-xhx9pzhj 2898 1 Eight eight CD cord-005646-xhx9pzhj 2898 2 of of IN cord-005646-xhx9pzhj 2898 3 the the DT cord-005646-xhx9pzhj 2898 4 13 13 CD cord-005646-xhx9pzhj 2898 5 hospitalised hospitalise VBN cord-005646-xhx9pzhj 2898 6 patients patient NNS cord-005646-xhx9pzhj 2898 7 were be VBD cord-005646-xhx9pzhj 2898 8 discharged discharge VBN cord-005646-xhx9pzhj 2898 9 , , , cord-005646-xhx9pzhj 2898 10 6 6 CD cord-005646-xhx9pzhj 2898 11 of of IN cord-005646-xhx9pzhj 2898 12 them -PRON- PRP cord-005646-xhx9pzhj 2898 13 with with IN cord-005646-xhx9pzhj 2898 14 mild mild JJ cord-005646-xhx9pzhj 2898 15 or or CC cord-005646-xhx9pzhj 2898 16 no no DT cord-005646-xhx9pzhj 2898 17 disability disability NN cord-005646-xhx9pzhj 2898 18 , , , cord-005646-xhx9pzhj 2898 19 1 1 CD cord-005646-xhx9pzhj 2898 20 with with IN cord-005646-xhx9pzhj 2898 21 moderate moderate JJ cord-005646-xhx9pzhj 2898 22 disability disability NN cord-005646-xhx9pzhj 2898 23 and and CC cord-005646-xhx9pzhj 2898 24 one one CD cord-005646-xhx9pzhj 2898 25 in in IN cord-005646-xhx9pzhj 2898 26 vegetative vegetative JJ cord-005646-xhx9pzhj 2898 27 state state NN cord-005646-xhx9pzhj 2898 28 . . . cord-005646-xhx9pzhj 2899 1 In in IN cord-005646-xhx9pzhj 2899 2 multivariate multivariate JJ cord-005646-xhx9pzhj 2899 3 analysis analysis NN cord-005646-xhx9pzhj 2899 4 the the DT cord-005646-xhx9pzhj 2899 5 short short JJ cord-005646-xhx9pzhj 2899 6 duration duration NN cord-005646-xhx9pzhj 2899 7 of of IN cord-005646-xhx9pzhj 2899 8 CPR CPR NNP cord-005646-xhx9pzhj 2899 9 ( ( -LRB- cord-005646-xhx9pzhj 2899 10 < < NNP cord-005646-xhx9pzhj 2899 11 16 16 CD cord-005646-xhx9pzhj 2899 12 minutes minute NNS cord-005646-xhx9pzhj 2899 13 ) ) -RRB- cord-005646-xhx9pzhj 2899 14 was be VBD cord-005646-xhx9pzhj 2899 15 the the DT cord-005646-xhx9pzhj 2899 16 only only JJ cord-005646-xhx9pzhj 2899 17 factor factor NN cord-005646-xhx9pzhj 2899 18 significantly significantly RB cord-005646-xhx9pzhj 2899 19 associated associate VBN cord-005646-xhx9pzhj 2899 20 with with IN cord-005646-xhx9pzhj 2899 21 better well JJR cord-005646-xhx9pzhj 2899 22 survival survival NN cord-005646-xhx9pzhj 2899 23 . . . cord-005646-xhx9pzhj 2900 1 Due due IN cord-005646-xhx9pzhj 2900 2 to to IN cord-005646-xhx9pzhj 2900 3 various various JJ cord-005646-xhx9pzhj 2900 4 aetiologies aetiology NNS cord-005646-xhx9pzhj 2900 5 the the DT cord-005646-xhx9pzhj 2900 6 survival survival NN cord-005646-xhx9pzhj 2900 7 rate rate NN cord-005646-xhx9pzhj 2900 8 from from IN cord-005646-xhx9pzhj 2900 9 prehospital prehospital JJ cord-005646-xhx9pzhj 2900 10 paediatric paediatric JJ cord-005646-xhx9pzhj 2900 11 cardiac cardiac JJ cord-005646-xhx9pzhj 2900 12 arrest arrest NN cord-005646-xhx9pzhj 2900 13 is be VBZ cord-005646-xhx9pzhj 2900 14 quite quite RB cord-005646-xhx9pzhj 2900 15 low low JJ cord-005646-xhx9pzhj 2900 16 . . . cord-005646-xhx9pzhj 2901 1 On on IN cord-005646-xhx9pzhj 2901 2 the the DT cord-005646-xhx9pzhj 2901 3 other other JJ cord-005646-xhx9pzhj 2901 4 hand hand NN cord-005646-xhx9pzhj 2901 5 , , , cord-005646-xhx9pzhj 2901 6 hypothermic hypothermic JJ cord-005646-xhx9pzhj 2901 7 near near RB cord-005646-xhx9pzhj 2901 8 - - HYPH cord-005646-xhx9pzhj 2901 9 drowning drown VBG cord-005646-xhx9pzhj 2901 10 victims victim NNS cord-005646-xhx9pzhj 2901 11 seem seem VBP cord-005646-xhx9pzhj 2901 12 to to TO cord-005646-xhx9pzhj 2901 13 have have VB cord-005646-xhx9pzhj 2901 14 a a DT cord-005646-xhx9pzhj 2901 15 relatively relatively RB cord-005646-xhx9pzhj 2901 16 good good JJ cord-005646-xhx9pzhj 2901 17 prognosis prognosis NN cord-005646-xhx9pzhj 2901 18 . . . cord-005646-xhx9pzhj 2902 1 Duration duration NN cord-005646-xhx9pzhj 2902 2 of of IN cord-005646-xhx9pzhj 2902 3 CPR CPR NNP cord-005646-xhx9pzhj 2902 4 less less JJR cord-005646-xhx9pzhj 2902 5 than than IN cord-005646-xhx9pzhj 2902 6 16 16 CD cord-005646-xhx9pzhj 2902 7 minutes minute NNS cord-005646-xhx9pzhj 2902 8 was be VBD cord-005646-xhx9pzhj 2902 9 the the DT cord-005646-xhx9pzhj 2902 10 best good JJS cord-005646-xhx9pzhj 2902 11 predictor predictor NN cord-005646-xhx9pzhj 2902 12 of of IN cord-005646-xhx9pzhj 2902 13 intact intact JJ cord-005646-xhx9pzhj 2902 14 survival survival NN cord-005646-xhx9pzhj 2902 15 , , , cord-005646-xhx9pzhj 2902 16 Our -PRON- PRP$ cord-005646-xhx9pzhj 2902 17 study study NN cord-005646-xhx9pzhj 2902 18 supports support VBZ cord-005646-xhx9pzhj 2902 19 the the DT cord-005646-xhx9pzhj 2902 20 previous previous JJ cord-005646-xhx9pzhj 2902 21 findings finding NNS cord-005646-xhx9pzhj 2902 22 of of IN cord-005646-xhx9pzhj 2902 23 the the DT cord-005646-xhx9pzhj 2902 24 importance importance NN cord-005646-xhx9pzhj 2902 25 of of IN cord-005646-xhx9pzhj 2902 26 early early JJ cord-005646-xhx9pzhj 2902 27 and and CC cord-005646-xhx9pzhj 2902 28 effective effective JJ cord-005646-xhx9pzhj 2902 29 resuscitation resuscitation NN cord-005646-xhx9pzhj 2902 30 efforts effort NNS cord-005646-xhx9pzhj 2902 31 for for IN cord-005646-xhx9pzhj 2902 32 establishing establish VBG cord-005646-xhx9pzhj 2902 33 ventilation ventilation NN cord-005646-xhx9pzhj 2902 34 and and CC cord-005646-xhx9pzhj 2902 35 perfusion perfusion NN cord-005646-xhx9pzhj 2902 36 on on IN cord-005646-xhx9pzhj 2902 37 the the DT cord-005646-xhx9pzhj 2902 38 scene scene NN cord-005646-xhx9pzhj 2902 39 . . . cord-005646-xhx9pzhj 2903 1 In in IN cord-005646-xhx9pzhj 2903 2 our -PRON- PRP$ cord-005646-xhx9pzhj 2903 3 system system NN cord-005646-xhx9pzhj 2903 4 well well RB cord-005646-xhx9pzhj 2903 5 trained train VBN cord-005646-xhx9pzhj 2903 6 physician physician NN cord-005646-xhx9pzhj 2903 7 staffed staffed JJ cord-005646-xhx9pzhj 2903 8 emergency emergency NN cord-005646-xhx9pzhj 2903 9 care care NN cord-005646-xhx9pzhj 2903 10 units unit NNS cord-005646-xhx9pzhj 2903 11 are be VBP cord-005646-xhx9pzhj 2903 12 able able JJ cord-005646-xhx9pzhj 2903 13 to to TO cord-005646-xhx9pzhj 2903 14 provide provide VB cord-005646-xhx9pzhj 2903 15 immediate immediate JJ cord-005646-xhx9pzhj 2903 16 and and CC cord-005646-xhx9pzhj 2903 17 effective effective JJ cord-005646-xhx9pzhj 2903 18 ALS als NN cord-005646-xhx9pzhj 2903 19 on on IN cord-005646-xhx9pzhj 2903 20 the the DT cord-005646-xhx9pzhj 2903 21 scene scene NN cord-005646-xhx9pzhj 2903 22 . . . cord-005646-xhx9pzhj 2904 1 On on IN cord-005646-xhx9pzhj 2904 2 the the DT cord-005646-xhx9pzhj 2904 3 other other JJ cord-005646-xhx9pzhj 2904 4 hand hand NN cord-005646-xhx9pzhj 2904 5 , , , cord-005646-xhx9pzhj 2904 6 these these DT cord-005646-xhx9pzhj 2904 7 units unit NNS cord-005646-xhx9pzhj 2904 8 also also RB cord-005646-xhx9pzhj 2904 9 appear appear VBP cord-005646-xhx9pzhj 2904 10 to to TO cord-005646-xhx9pzhj 2904 11 be be VB cord-005646-xhx9pzhj 2904 12 able able JJ cord-005646-xhx9pzhj 2904 13 to to TO cord-005646-xhx9pzhj 2904 14 refrain refrain VB cord-005646-xhx9pzhj 2904 15 from from IN cord-005646-xhx9pzhj 2904 16 resuscitation resuscitation NN cord-005646-xhx9pzhj 2904 17 when when WRB cord-005646-xhx9pzhj 2904 18 the the DT cord-005646-xhx9pzhj 2904 19 prognosis prognosis NN cord-005646-xhx9pzhj 2904 20 is be VBZ cord-005646-xhx9pzhj 2904 21 pessimistic pessimistic JJ cord-005646-xhx9pzhj 2904 22 . . . cord-005646-xhx9pzhj 2905 1 Objective objective NN cord-005646-xhx9pzhj 2905 2 : : : cord-005646-xhx9pzhj 2905 3 To to TO cord-005646-xhx9pzhj 2905 4 assess assess VB cord-005646-xhx9pzhj 2905 5 the the DT cord-005646-xhx9pzhj 2905 6 normal normal JJ cord-005646-xhx9pzhj 2905 7 , , , cord-005646-xhx9pzhj 2905 8 gastric gastric JJ cord-005646-xhx9pzhj 2905 9 intramucosal intramucosal NN cord-005646-xhx9pzhj 2905 10 pH pH NNP cord-005646-xhx9pzhj 2905 11 ~Hi ~Hi NNP cord-005646-xhx9pzhj 2905 12 ) ) -RRB- cord-005646-xhx9pzhj 2905 13 by by IN cord-005646-xhx9pzhj 2905 14 tonometry tonometry NNP cord-005646-xhx9pzhj 2905 15 in in IN cord-005646-xhx9pzhj 2905 16 healthy healthy JJ cord-005646-xhx9pzhj 2905 17 children child NNS cord-005646-xhx9pzhj 2905 18 Patients patient NNS cord-005646-xhx9pzhj 2905 19 and and CC cord-005646-xhx9pzhj 2905 20 methods method NNS cord-005646-xhx9pzhj 2905 21 : : : cord-005646-xhx9pzhj 2905 22 Twelve twelve CD cord-005646-xhx9pzhj 2905 23 healthy healthy JJ cord-005646-xhx9pzhj 2905 24 children child NNS cord-005646-xhx9pzhj 2905 25 ( ( -LRB- cord-005646-xhx9pzhj 2905 26 6 6 CD cord-005646-xhx9pzhj 2905 27 males male NNS cord-005646-xhx9pzhj 2905 28 and and CC cord-005646-xhx9pzhj 2905 29 6 6 CD cord-005646-xhx9pzhj 2905 30 females female NNS cord-005646-xhx9pzhj 2905 31 ) ) -RRB- cord-005646-xhx9pzhj 2905 32 with with IN cord-005646-xhx9pzhj 2905 33 age age NN cord-005646-xhx9pzhj 2905 34 rmaged rmage VBN cord-005646-xhx9pzhj 2905 35 from from IN cord-005646-xhx9pzhj 2905 36 6 6 CD cord-005646-xhx9pzhj 2905 37 months month NNS cord-005646-xhx9pzhj 2905 38 to to IN cord-005646-xhx9pzhj 2905 39 12 12 CD cord-005646-xhx9pzhj 2905 40 years year NNS cord-005646-xhx9pzhj 2905 41 scheduled schedule VBN cord-005646-xhx9pzhj 2905 42 for for IN cord-005646-xhx9pzhj 2905 43 minor minor JJ cord-005646-xhx9pzhj 2905 44 plastic plastic NN cord-005646-xhx9pzhj 2905 45 or or CC cord-005646-xhx9pzhj 2905 46 urologic urologic JJ cord-005646-xhx9pzhj 2905 47 surgery surgery NN cord-005646-xhx9pzhj 2905 48 . . . cord-005646-xhx9pzhj 2906 1 Children child NNS cord-005646-xhx9pzhj 2906 2 were be VBD cord-005646-xhx9pzhj 2906 3 previously previously RB cord-005646-xhx9pzhj 2906 4 medicated medicate VBN cord-005646-xhx9pzhj 2906 5 with with IN cord-005646-xhx9pzhj 2906 6 midazolam midazolam NNP cord-005646-xhx9pzhj 2906 7 ( ( -LRB- cord-005646-xhx9pzhj 2906 8 0.25 0.25 CD cord-005646-xhx9pzhj 2906 9 mg mg NNP cord-005646-xhx9pzhj 2906 10 / / SYM cord-005646-xhx9pzhj 2906 11 kg kg NNP cord-005646-xhx9pzhj 2906 12 ) ) -RRB- cord-005646-xhx9pzhj 2906 13 and and CC cord-005646-xhx9pzhj 2906 14 atropine atropine NN cord-005646-xhx9pzhj 2906 15 ( ( -LRB- cord-005646-xhx9pzhj 2906 16 0.02 0.02 CD cord-005646-xhx9pzhj 2906 17 mg~ mg~ NNP cord-005646-xhx9pzhj 2906 18 ) ) -RRB- cord-005646-xhx9pzhj 2907 1 both both DT cord-005646-xhx9pzhj 2908 1 i.m i.m NNP cord-005646-xhx9pzhj 2908 2 .. .. . cord-005646-xhx9pzhj 2909 1 Anaesthetic anaesthetic JJ cord-005646-xhx9pzhj 2909 2 induction induction NN cord-005646-xhx9pzhj 2909 3 was be VBD cord-005646-xhx9pzhj 2909 4 standardized standardize VBN cord-005646-xhx9pzhj 2909 5 with with IN cord-005646-xhx9pzhj 2909 6 02 02 CD cord-005646-xhx9pzhj 2909 7 -N20 -N20 : cord-005646-xhx9pzhj 2909 8 ( ( -LRB- cord-005646-xhx9pzhj 2909 9 75 75 CD cord-005646-xhx9pzhj 2909 10 % % NN cord-005646-xhx9pzhj 2909 11 ) ) -RRB- cord-005646-xhx9pzhj 2909 12 administered administer VBN cord-005646-xhx9pzhj 2909 13 via via IN cord-005646-xhx9pzhj 2909 14 facial facial JJ cord-005646-xhx9pzhj 2909 15 mask mask NN cord-005646-xhx9pzhj 2909 16 and and CC cord-005646-xhx9pzhj 2909 17 increased increase VBN cord-005646-xhx9pzhj 2909 18 halotane halotane NNP cord-005646-xhx9pzhj 2909 19 concentrations concentration NNS cord-005646-xhx9pzhj 2909 20 ( ( -LRB- cord-005646-xhx9pzhj 2909 21 up up IN cord-005646-xhx9pzhj 2909 22 to to TO cord-005646-xhx9pzhj 2909 23 2 2 CD cord-005646-xhx9pzhj 2909 24 % % NN cord-005646-xhx9pzhj 2909 25 ) ) -RRB- cord-005646-xhx9pzhj 2909 26 . . . cord-005646-xhx9pzhj 2910 1 All all DT cord-005646-xhx9pzhj 2910 2 patients patient NNS cord-005646-xhx9pzhj 2910 3 got get VBD cord-005646-xhx9pzhj 2910 4 an an DT cord-005646-xhx9pzhj 2910 5 endotraeheal endotraeheal NN cord-005646-xhx9pzhj 2910 6 tube tube NN cord-005646-xhx9pzhj 2910 7 after after IN cord-005646-xhx9pzhj 2910 8 iv iv NNP cord-005646-xhx9pzhj 2910 9 . . . cord-005646-xhx9pzhj 2911 1 administration administration NNP cord-005646-xhx9pzhj 2911 2 of of IN cord-005646-xhx9pzhj 2911 3 femanile femanile NNP cord-005646-xhx9pzhj 2911 4 ( ( -LRB- cord-005646-xhx9pzhj 2911 5 2 2 CD cord-005646-xhx9pzhj 2911 6 mcg mcg NN cord-005646-xhx9pzhj 2911 7 : : : cord-005646-xhx9pzhj 2911 8 Jkg Jkg NNP cord-005646-xhx9pzhj 2911 9 ) ) -RRB- cord-005646-xhx9pzhj 2911 10 and and CC cord-005646-xhx9pzhj 2911 11 vecuronium vecuronium NNP cord-005646-xhx9pzhj 2911 12 ( ( -LRB- cord-005646-xhx9pzhj 2911 13 0.1 0.1 CD cord-005646-xhx9pzhj 2911 14 mg mg NNP cord-005646-xhx9pzhj 2911 15 / / SYM cord-005646-xhx9pzhj 2911 16 kg kg NNP cord-005646-xhx9pzhj 2911 17 ) ) -RRB- cord-005646-xhx9pzhj 2911 18 or or CC cord-005646-xhx9pzhj 2911 19 suxametonio suxametonio NNP cord-005646-xhx9pzhj 2911 20 ( ( -LRB- cord-005646-xhx9pzhj 2911 21 1 1 CD cord-005646-xhx9pzhj 2911 22 mg mg NNP cord-005646-xhx9pzhj 2911 23 / / SYM cord-005646-xhx9pzhj 2911 24 kg kg NNP cord-005646-xhx9pzhj 2911 25 ) ) -RRB- cord-005646-xhx9pzhj 2911 26 , , , cord-005646-xhx9pzhj 2911 27 Pmaesthesia Pmaesthesia NNP cord-005646-xhx9pzhj 2911 28 was be VBD cord-005646-xhx9pzhj 2911 29 maintained maintain VBN cord-005646-xhx9pzhj 2911 30 with with IN cord-005646-xhx9pzhj 2911 31 O o NN cord-005646-xhx9pzhj 2911 32 2 2 CD cord-005646-xhx9pzhj 2911 33 -N20 -N20 : cord-005646-xhx9pzhj 2911 34 ( ( -LRB- cord-005646-xhx9pzhj 2911 35 60 60 CD cord-005646-xhx9pzhj 2911 36 - - SYM cord-005646-xhx9pzhj 2911 37 75 75 CD cord-005646-xhx9pzhj 2911 38 % % NN cord-005646-xhx9pzhj 2911 39 ) ) -RRB- cord-005646-xhx9pzhj 2911 40 and and CC cord-005646-xhx9pzhj 2911 41 isofluorane isofluorane NNP cord-005646-xhx9pzhj 2911 42 ( ( -LRB- cord-005646-xhx9pzhj 2911 43 0.5 0.5 CD cord-005646-xhx9pzhj 2911 44 - - SYM cord-005646-xhx9pzhj 2911 45 1 1 CD cord-005646-xhx9pzhj 2911 46 % % NN cord-005646-xhx9pzhj 2911 47 ) ) -RRB- cord-005646-xhx9pzhj 2911 48 . . . cord-005646-xhx9pzhj 2912 1 During during IN cord-005646-xhx9pzhj 2912 2 surgery surgery NN cord-005646-xhx9pzhj 2912 3 , , , cord-005646-xhx9pzhj 2912 4 8 8 CD cord-005646-xhx9pzhj 2912 5 children child NNS cord-005646-xhx9pzhj 2912 6 needed need VBD cord-005646-xhx9pzhj 2912 7 mechanical mechanical JJ cord-005646-xhx9pzhj 2912 8 ventilation ventilation NN cord-005646-xhx9pzhj 2912 9 and and CC cord-005646-xhx9pzhj 2912 10 the the DT cord-005646-xhx9pzhj 2912 11 others other NNS cord-005646-xhx9pzhj 2912 12 maintained maintain VBD cord-005646-xhx9pzhj 2912 13 spontaneous spontaneous JJ cord-005646-xhx9pzhj 2912 14 breathing breathing NN cord-005646-xhx9pzhj 2912 15 . . . cord-005646-xhx9pzhj 2913 1 EKG EKG NNP cord-005646-xhx9pzhj 2913 2 , , , cord-005646-xhx9pzhj 2913 3 heart heart NN cord-005646-xhx9pzhj 2913 4 rate rate NN cord-005646-xhx9pzhj 2913 5 , , , cord-005646-xhx9pzhj 2913 6 blood blood NN cord-005646-xhx9pzhj 2913 7 pressure pressure NN cord-005646-xhx9pzhj 2913 8 , , , cord-005646-xhx9pzhj 2913 9 and and CC cord-005646-xhx9pzhj 2913 10 pulse pulse NN cord-005646-xhx9pzhj 2913 11 oximetry oximetry NN cord-005646-xhx9pzhj 2913 12 were be VBD cord-005646-xhx9pzhj 2913 13 moniterized moniterize VBN cord-005646-xhx9pzhj 2913 14 . . . cord-005646-xhx9pzhj 2914 1 After after IN cord-005646-xhx9pzhj 2914 2 anaesthesia anaesthesia NN cord-005646-xhx9pzhj 2914 3 , , , cord-005646-xhx9pzhj 2914 4 a a DT cord-005646-xhx9pzhj 2914 5 sigmoid sigmoid JJ cord-005646-xhx9pzhj 2914 6 tenometry tenometry NN cord-005646-xhx9pzhj 2914 7 catheter catheter NN cord-005646-xhx9pzhj 2914 8 ( ( -LRB- cord-005646-xhx9pzhj 2914 9 Tonometrics Tonometrics NNP cord-005646-xhx9pzhj 2914 10 , , , cord-005646-xhx9pzhj 2914 11 Inc. Inc. NNP cord-005646-xhx9pzhj 2914 12 ) ) -RRB- cord-005646-xhx9pzhj 2914 13 was be VBD cord-005646-xhx9pzhj 2914 14 inserted insert VBN cord-005646-xhx9pzhj 2914 15 in in IN cord-005646-xhx9pzhj 2914 16 the the DT cord-005646-xhx9pzhj 2914 17 stomach stomach NN cord-005646-xhx9pzhj 2914 18 of of IN cord-005646-xhx9pzhj 2914 19 the the DT cord-005646-xhx9pzhj 2914 20 patients patient NNS cord-005646-xhx9pzhj 2914 21 by by IN cord-005646-xhx9pzhj 2914 22 direct direct JJ cord-005646-xhx9pzhj 2914 23 visualization visualization NN cord-005646-xhx9pzhj 2914 24 with with IN cord-005646-xhx9pzhj 2914 25 laryngoscope laryngoscope NN cord-005646-xhx9pzhj 2914 26 and and CC cord-005646-xhx9pzhj 2914 27 Magyll Magyll NNP cord-005646-xhx9pzhj 2914 28 clamps clamp NNS cord-005646-xhx9pzhj 2914 29 . . . cord-005646-xhx9pzhj 2915 1 Children child NNS cord-005646-xhx9pzhj 2915 2 were be VBD cord-005646-xhx9pzhj 2915 3 all all DT cord-005646-xhx9pzhj 2915 4 maintained maintain VBN cord-005646-xhx9pzhj 2915 5 normoventilated normoventilated JJ cord-005646-xhx9pzhj 2915 6 and and CC cord-005646-xhx9pzhj 2915 7 with with IN cord-005646-xhx9pzhj 2915 8 normal normal JJ cord-005646-xhx9pzhj 2915 9 cardiorespiratery cardiorespiratery NN cord-005646-xhx9pzhj 2915 10 variables variable NNS cord-005646-xhx9pzhj 2915 11 . . . cord-005646-xhx9pzhj 2916 1 Cadet Cadet NNP cord-005646-xhx9pzhj 2916 2 's 's POS cord-005646-xhx9pzhj 2916 3 balloon balloon NN cord-005646-xhx9pzhj 2916 4 was be VBD cord-005646-xhx9pzhj 2916 5 £ £ $ cord-005646-xhx9pzhj 2916 6 ~led ~le VBN cord-005646-xhx9pzhj 2916 7 with with IN cord-005646-xhx9pzhj 2916 8 2.5 2.5 CD cord-005646-xhx9pzhj 2916 9 ml ml NNS cord-005646-xhx9pzhj 2916 10 of of IN cord-005646-xhx9pzhj 2916 11 saline saline NN cord-005646-xhx9pzhj 2916 12 . . . cord-005646-xhx9pzhj 2917 1 Thirty thirty CD cord-005646-xhx9pzhj 2917 2 minutes minute NNS cord-005646-xhx9pzhj 2917 3 after after IN cord-005646-xhx9pzhj 2917 4 the the DT cord-005646-xhx9pzhj 2917 5 insertion insertion NN cord-005646-xhx9pzhj 2917 6 1 1 CD cord-005646-xhx9pzhj 2917 7 rrd rrd NN cord-005646-xhx9pzhj 2917 8 was be VBD cord-005646-xhx9pzhj 2917 9 extracted extract VBN cord-005646-xhx9pzhj 2917 10 and and CC cord-005646-xhx9pzhj 2917 11 rejected reject VBN cord-005646-xhx9pzhj 2917 12 , , , cord-005646-xhx9pzhj 2917 13 just just RB cord-005646-xhx9pzhj 2917 14 afterwards afterwards RB cord-005646-xhx9pzhj 2917 15 the the DT cord-005646-xhx9pzhj 2917 16 remanent remanent JJ cord-005646-xhx9pzhj 2917 17 1.5 1.5 CD cord-005646-xhx9pzhj 2917 18 ml ml NNS cord-005646-xhx9pzhj 2917 19 was be VBD cord-005646-xhx9pzhj 2917 20 extracted extract VBN cord-005646-xhx9pzhj 2917 21 and and CC cord-005646-xhx9pzhj 2917 22 immediately immediately RB cord-005646-xhx9pzhj 2917 23 analyzed analyze VBN cord-005646-xhx9pzhj 2917 24 . . . cord-005646-xhx9pzhj 2918 1 Simultaneously simultaneously RB cord-005646-xhx9pzhj 2918 2 an an DT cord-005646-xhx9pzhj 2918 3 arterial arterial JJ cord-005646-xhx9pzhj 2918 4 gasometry gasometry NN cord-005646-xhx9pzhj 2918 5 by by IN cord-005646-xhx9pzhj 2918 6 puncture puncture NN cord-005646-xhx9pzhj 2918 7 was be VBD cord-005646-xhx9pzhj 2918 8 performed perform VBN cord-005646-xhx9pzhj 2918 9 . . . cord-005646-xhx9pzhj 2919 1 Gastric gastric JJ cord-005646-xhx9pzhj 2919 2 pHi pHi NNS cord-005646-xhx9pzhj 2919 3 was be VBD cord-005646-xhx9pzhj 2919 4 calculated calculate VBN cord-005646-xhx9pzhj 2919 5 by by IN cord-005646-xhx9pzhj 2919 6 the the DT cord-005646-xhx9pzhj 2919 7 Henderson Henderson NNP cord-005646-xhx9pzhj 2919 8 - - HYPH cord-005646-xhx9pzhj 2919 9 Hasselbalch Hasselbalch NNP cord-005646-xhx9pzhj 2919 10 's 's POS cord-005646-xhx9pzhj 2919 11 equation equation NN cord-005646-xhx9pzhj 2919 12 using use VBG cord-005646-xhx9pzhj 2919 13 the the DT cord-005646-xhx9pzhj 2919 14 pCO pco CD cord-005646-xhx9pzhj 2919 15 2 2 CD cord-005646-xhx9pzhj 2919 16 obtained obtain VBN cord-005646-xhx9pzhj 2919 17 from from IN cord-005646-xhx9pzhj 2919 18 the the DT cord-005646-xhx9pzhj 2919 19 tenometry tenometry NN cord-005646-xhx9pzhj 2919 20 catheter catheter NN cord-005646-xhx9pzhj 2919 21 and and CC cord-005646-xhx9pzhj 2919 22 the the DT cord-005646-xhx9pzhj 2919 23 bicarbonate bicarbonate NN cord-005646-xhx9pzhj 2919 24 value value NN cord-005646-xhx9pzhj 2919 25 obtained obtain VBN cord-005646-xhx9pzhj 2919 26 from from IN cord-005646-xhx9pzhj 2919 27 the the DT cord-005646-xhx9pzhj 2919 28 arterial arterial JJ cord-005646-xhx9pzhj 2919 29 gasometry gasometry NN cord-005646-xhx9pzhj 2919 30 . . . cord-005646-xhx9pzhj 2920 1 Results result NNS cord-005646-xhx9pzhj 2920 2 : : : cord-005646-xhx9pzhj 2921 1 Average average JJ cord-005646-xhx9pzhj 2921 2 gastric gastric JJ cord-005646-xhx9pzhj 2921 3 phi phi NN cord-005646-xhx9pzhj 2921 4 was be VBD cord-005646-xhx9pzhj 2921 5 7.34 7.34 CD cord-005646-xhx9pzhj 2921 6 -I-0.027 -i-0.027 NN cord-005646-xhx9pzhj 2921 7 , , , cord-005646-xhx9pzhj 2921 8 range range NNP cord-005646-xhx9pzhj 2921 9 ( ( -LRB- cord-005646-xhx9pzhj 2921 10 7.29 7.29 CD cord-005646-xhx9pzhj 2921 11 - - HYPH cord-005646-xhx9pzhj 2921 12 7.46 7.46 CD cord-005646-xhx9pzhj 2921 13 ) ) -RRB- cord-005646-xhx9pzhj 2921 14 . . . cord-005646-xhx9pzhj 2922 1 Objective objective JJ cord-005646-xhx9pzhj 2922 2 : : : cord-005646-xhx9pzhj 2922 3 Demons demon NNS cord-005646-xhx9pzhj 2922 4 ~ ~ NFP cord-005646-xhx9pzhj 2922 5 ating ate VBG cord-005646-xhx9pzhj 2922 6 intramucesaI intramucesaI NNP cord-005646-xhx9pzhj 2922 7 pH pH NNP cord-005646-xhx9pzhj 2922 8 ( ( -LRB- cord-005646-xhx9pzhj 2922 9 pHi pHi NNP cord-005646-xhx9pzhj 2922 10 ) ) -RRB- cord-005646-xhx9pzhj 2922 11 alterations alteration NNS cord-005646-xhx9pzhj 2922 12 during during IN cord-005646-xhx9pzhj 2922 13 transport transport NN cord-005646-xhx9pzhj 2922 14 of of IN cord-005646-xhx9pzhj 2922 15 patients patient NNS cord-005646-xhx9pzhj 2922 16 from from IN cord-005646-xhx9pzhj 2922 17 operative operative JJ cord-005646-xhx9pzhj 2922 18 room room NN cord-005646-xhx9pzhj 2922 19 to to IN cord-005646-xhx9pzhj 2922 20 pediatric pediatric JJ cord-005646-xhx9pzhj 2922 21 intensive intensive JJ cord-005646-xhx9pzhj 2922 22 care care NN cord-005646-xhx9pzhj 2922 23 unit unit NN cord-005646-xhx9pzhj 2922 24 ( ( -LRB- cord-005646-xhx9pzhj 2922 25 PICU PICU NNP cord-005646-xhx9pzhj 2922 26 ) ) -RRB- cord-005646-xhx9pzhj 2922 27 , , , cord-005646-xhx9pzhj 2922 28 Material material NN cord-005646-xhx9pzhj 2922 29 and and CC cord-005646-xhx9pzhj 2922 30 methods method NNS cord-005646-xhx9pzhj 2922 31 : : : cord-005646-xhx9pzhj 2922 32 pHi phi JJ cord-005646-xhx9pzhj 2922 33 measurements measurement NNS cord-005646-xhx9pzhj 2922 34 were be VBD cord-005646-xhx9pzhj 2922 35 performed perform VBN cord-005646-xhx9pzhj 2922 36 with with IN cord-005646-xhx9pzhj 2922 37 gastric gastric JJ cord-005646-xhx9pzhj 2922 38 tonometer tonometer NN cord-005646-xhx9pzhj 2922 39 catheter catheter NN cord-005646-xhx9pzhj 2922 40 in in IN cord-005646-xhx9pzhj 2922 41 t4 t4 NNP cord-005646-xhx9pzhj 2922 42 patients patient NNS cord-005646-xhx9pzhj 2922 43 undergoing undergo VBG cord-005646-xhx9pzhj 2922 44 cardiac cardiac JJ cord-005646-xhx9pzhj 2922 45 surgery surgery NN cord-005646-xhx9pzhj 2922 46 with with IN cord-005646-xhx9pzhj 2922 47 cardiopulmona cardiopulmona NNP cord-005646-xhx9pzhj 2922 48 D D NNP cord-005646-xhx9pzhj 2922 49 " " '' cord-005646-xhx9pzhj 2922 50 bypass bypass NN cord-005646-xhx9pzhj 2922 51 ( ( -LRB- cord-005646-xhx9pzhj 2922 52 CPB CPB NNP cord-005646-xhx9pzhj 2922 53 ) ) -RRB- cord-005646-xhx9pzhj 2922 54 , , , cord-005646-xhx9pzhj 2922 55 There there EX cord-005646-xhx9pzhj 2922 56 was be VBD cord-005646-xhx9pzhj 2922 57 9 9 CD cord-005646-xhx9pzhj 2922 58 mate mate NN cord-005646-xhx9pzhj 2922 59 and and CC cord-005646-xhx9pzhj 2922 60 5 5 CD cord-005646-xhx9pzhj 2922 61 female female NN cord-005646-xhx9pzhj 2922 62 , , , cord-005646-xhx9pzhj 2922 63 the the DT cord-005646-xhx9pzhj 2922 64 average average JJ cord-005646-xhx9pzhj 2922 65 age age NN cord-005646-xhx9pzhj 2922 66 = = SYM cord-005646-xhx9pzhj 2922 67 3yl0ra 3yl0ra CD cord-005646-xhx9pzhj 2922 68 , , , cord-005646-xhx9pzhj 2922 69 average average JJ cord-005646-xhx9pzhj 2922 70 weight weight NN cord-005646-xhx9pzhj 2922 71 = = SYM cord-005646-xhx9pzhj 2922 72 12,5 12,5 CD cord-005646-xhx9pzhj 2922 73 kg kg NN cord-005646-xhx9pzhj 2922 74 , , , cord-005646-xhx9pzhj 2922 75 average average JJ cord-005646-xhx9pzhj 2922 76 time time NN cord-005646-xhx9pzhj 2922 77 of of IN cord-005646-xhx9pzhj 2922 78 CPB CPB NNP cord-005646-xhx9pzhj 2922 79 = = SYM cord-005646-xhx9pzhj 2922 80 70 70 CD cord-005646-xhx9pzhj 2922 81 rain rain NN cord-005646-xhx9pzhj 2922 82 . . . cord-005646-xhx9pzhj 2923 1 The the DT cord-005646-xhx9pzhj 2923 2 measurements measurement NNS cord-005646-xhx9pzhj 2923 3 were be VBD cord-005646-xhx9pzhj 2923 4 made make VBN cord-005646-xhx9pzhj 2923 5 at at IN cord-005646-xhx9pzhj 2923 6 the the DT cord-005646-xhx9pzhj 2923 7 end end NN cord-005646-xhx9pzhj 2923 8 of of IN cord-005646-xhx9pzhj 2923 9 the the DT cord-005646-xhx9pzhj 2923 10 surgeD surgeD NNP cord-005646-xhx9pzhj 2923 11 ' ' '' cord-005646-xhx9pzhj 2923 12 and and CC cord-005646-xhx9pzhj 2923 13 when when WRB cord-005646-xhx9pzhj 2923 14 the the DT cord-005646-xhx9pzhj 2923 15 patients patient NNS cord-005646-xhx9pzhj 2923 16 had have VBD cord-005646-xhx9pzhj 2923 17 arrived arrive VBN cord-005646-xhx9pzhj 2923 18 in in IN cord-005646-xhx9pzhj 2923 19 the the DT cord-005646-xhx9pzhj 2923 20 PICU PICU NNP cord-005646-xhx9pzhj 2923 21 Statistical Statistical NNP cord-005646-xhx9pzhj 2923 22 aualysis aualysis NN cord-005646-xhx9pzhj 2923 23 : : : cord-005646-xhx9pzhj 2924 1 Average average JJ cord-005646-xhx9pzhj 2924 2 and and CC cord-005646-xhx9pzhj 2924 3 ~andart ~andart NNP cord-005646-xhx9pzhj 2924 4 deviation deviation NN cord-005646-xhx9pzhj 2924 5 and and CC cord-005646-xhx9pzhj 2924 6 test test NN cord-005646-xhx9pzhj 2924 7 " " `` cord-005646-xhx9pzhj 2924 8 t t NN cord-005646-xhx9pzhj 2924 9 " " '' cord-005646-xhx9pzhj 2924 10 Student Student NNP cord-005646-xhx9pzhj 2924 11 . . . cord-005646-xhx9pzhj 2925 1 Objetive Objetive NNP cord-005646-xhx9pzhj 2925 2 : : : cord-005646-xhx9pzhj 2926 1 To to IN cord-005646-xhx9pzhj 2926 2 asses ass NNS cord-005646-xhx9pzhj 2926 3 the the DT cord-005646-xhx9pzhj 2926 4 efficacy efficacy NN cord-005646-xhx9pzhj 2926 5 of of IN cord-005646-xhx9pzhj 2926 6 gastric gastric JJ cord-005646-xhx9pzhj 2926 7 iatramucosad iatramucosad NNP cord-005646-xhx9pzhj 2926 8 ptt ptt NNP cord-005646-xhx9pzhj 2926 9 ( ( -LRB- cord-005646-xhx9pzhj 2926 10 pHi pHi NNP cord-005646-xhx9pzhj 2926 11 ) ) -RRB- cord-005646-xhx9pzhj 2926 12 and and CC cord-005646-xhx9pzhj 2926 13 arterial arterial JJ cord-005646-xhx9pzhj 2926 14 lactate lactate NN cord-005646-xhx9pzhj 2926 15 levels level NNS cord-005646-xhx9pzhj 2926 16 to to TO cord-005646-xhx9pzhj 2926 17 evaluate evaluate VB cord-005646-xhx9pzhj 2926 18 splacalc splacalc NNP cord-005646-xhx9pzhj 2926 19 tissular tissular JJ cord-005646-xhx9pzhj 2926 20 perfusion perfusion NN cord-005646-xhx9pzhj 2926 21 in in IN cord-005646-xhx9pzhj 2926 22 an an DT cord-005646-xhx9pzhj 2926 23 experimental experimental JJ cord-005646-xhx9pzhj 2926 24 model model NN cord-005646-xhx9pzhj 2926 25 of of IN cord-005646-xhx9pzhj 2926 26 intestinal intestinal JJ cord-005646-xhx9pzhj 2926 27 ischemia ischemia NN cord-005646-xhx9pzhj 2926 28 . . . cord-005646-xhx9pzhj 2927 1 SuNeets SuNeets NNP cord-005646-xhx9pzhj 2928 1 ~nd ~nd NNP cord-005646-xhx9pzhj 2929 1 methods method NNS cord-005646-xhx9pzhj 2929 2 : : : cord-005646-xhx9pzhj 2930 1 twelve twelve CD cord-005646-xhx9pzhj 2930 2 piglets piglet NNS cord-005646-xhx9pzhj 2930 3 weights weight VBZ cord-005646-xhx9pzhj 2930 4 t3 t3 NNP cord-005646-xhx9pzhj 2930 5 - - HYPH cord-005646-xhx9pzhj 2930 6 20 20 CD cord-005646-xhx9pzhj 2930 7 Kgs kg NNS cord-005646-xhx9pzhj 2930 8 . . . cord-005646-xhx9pzhj 2931 1 undergoing undergo VBG cord-005646-xhx9pzhj 2931 2 orthot orthot NNP cord-005646-xhx9pzhj 2931 3 ~ ~ CD cord-005646-xhx9pzhj 2931 4 ie ie NNP cord-005646-xhx9pzhj 2931 5 liver liver NNP cord-005646-xhx9pzhj 2931 6 trasplantation trasplantation NNP cord-005646-xhx9pzhj 2931 7 . . . cord-005646-xhx9pzhj 2932 1 The the DT cord-005646-xhx9pzhj 2932 2 intestinal intestinal JJ cord-005646-xhx9pzhj 2932 3 ischemia ischemia NN cord-005646-xhx9pzhj 2932 4 was be VBD cord-005646-xhx9pzhj 2932 5 induced induce VBN cord-005646-xhx9pzhj 2932 6 by by IN cord-005646-xhx9pzhj 2932 7 aortic aortic JJ cord-005646-xhx9pzhj 2932 8 damping damping NN cord-005646-xhx9pzhj 2932 9 . . . cord-005646-xhx9pzhj 2933 1 Tonometry Tonometry NNP cord-005646-xhx9pzhj 2933 2 catheter catheter NN cord-005646-xhx9pzhj 2933 3 ( ( -LRB- cord-005646-xhx9pzhj 2933 4 Tonometrics Tonometrics NNP cord-005646-xhx9pzhj 2933 5 Inc. Inc. NNP cord-005646-xhx9pzhj 2933 6 ) ) -RRB- cord-005646-xhx9pzhj 2934 1 w~ w~ : cord-005646-xhx9pzhj 2935 1 s s NNP cord-005646-xhx9pzhj 2935 2 placed place VBD cord-005646-xhx9pzhj 2935 3 in in IN cord-005646-xhx9pzhj 2935 4 the the DT cord-005646-xhx9pzhj 2935 5 stomach stomach NN cord-005646-xhx9pzhj 2935 6 after after IN cord-005646-xhx9pzhj 2935 7 artaesthesia artaesthesia NNP cord-005646-xhx9pzhj 2935 8 and and CC cord-005646-xhx9pzhj 2935 9 OT OT NNP cord-005646-xhx9pzhj 2935 10 intubation intubation NN cord-005646-xhx9pzhj 2935 11 . . . cord-005646-xhx9pzhj 2936 1 PHi PHi NNP cord-005646-xhx9pzhj 2937 1 ~s ~s NNP cord-005646-xhx9pzhj 2937 2 determined determine VBD cord-005646-xhx9pzhj 2937 3 7 7 CD cord-005646-xhx9pzhj 2937 4 times time NNS cord-005646-xhx9pzhj 2937 5 and and CC cord-005646-xhx9pzhj 2937 6 lactate lactate NN cord-005646-xhx9pzhj 2937 7 levels level NNS cord-005646-xhx9pzhj 2937 8 was be VBD cord-005646-xhx9pzhj 2937 9 determined determine VBN cord-005646-xhx9pzhj 2937 10 fi fi NNP cord-005646-xhx9pzhj 2937 11 times time NNS cord-005646-xhx9pzhj 2937 12 in in IN cord-005646-xhx9pzhj 2937 13 3 3 CD cord-005646-xhx9pzhj 2937 14 stages stage NNS cord-005646-xhx9pzhj 2937 15 : : : cord-005646-xhx9pzhj 2937 16 I i NN cord-005646-xhx9pzhj 2937 17 ) ) -RRB- cord-005646-xhx9pzhj 2938 1 Pre Pre NNP cord-005646-xhx9pzhj 2938 2 - - NN cord-005646-xhx9pzhj 2938 3 AE AE NNP cord-005646-xhx9pzhj 2938 4 ~ ~ NFP cord-005646-xhx9pzhj 2938 5 hepatic hepatic JJ cord-005646-xhx9pzhj 2938 6 stage stage NN cord-005646-xhx9pzhj 2938 7 ( ( -LRB- cord-005646-xhx9pzhj 2938 8 twice twice RB cord-005646-xhx9pzhj 2938 9 : : : cord-005646-xhx9pzhj 2938 10 before before IN cord-005646-xhx9pzhj 2938 11 surgery surgery NN cord-005646-xhx9pzhj 2938 12 and and CC cord-005646-xhx9pzhj 2938 13 before before IN cord-005646-xhx9pzhj 2938 14 aortic aortic JJ cord-005646-xhx9pzhj 2938 15 clamping clamping NN cord-005646-xhx9pzhj 2938 16 ) ) -RRB- cord-005646-xhx9pzhj 2938 17 ; ; : cord-005646-xhx9pzhj 2938 18 II ii LS cord-005646-xhx9pzhj 2938 19 ) ) -RRB- cord-005646-xhx9pzhj 2939 1 End end VB cord-005646-xhx9pzhj 2939 2 anhepatic anhepatic JJ cord-005646-xhx9pzhj 2939 3 stage stage NN cord-005646-xhx9pzhj 2939 4 ( ( -LRB- cord-005646-xhx9pzhj 2939 5 only only RB cord-005646-xhx9pzhj 2939 6 phi phi NN cord-005646-xhx9pzhj 2939 7 ) ) -RRB- cord-005646-xhx9pzhj 2939 8 : : : cord-005646-xhx9pzhj 2939 9 III iii CD cord-005646-xhx9pzhj 2939 10 ) ) -RRB- cord-005646-xhx9pzhj 2940 1 Reperfusion reperfusion NN cord-005646-xhx9pzhj 2940 2 stage stage NN cord-005646-xhx9pzhj 2940 3 ( ( -LRB- cord-005646-xhx9pzhj 2940 4 a a DT cord-005646-xhx9pzhj 2940 5 30 30 CD cord-005646-xhx9pzhj 2940 6 , , , cord-005646-xhx9pzhj 2940 7 90 90 CD cord-005646-xhx9pzhj 2940 8 , , , cord-005646-xhx9pzhj 2940 9 120 120 CD cord-005646-xhx9pzhj 2940 10 and and CC cord-005646-xhx9pzhj 2940 11 180 180 CD cord-005646-xhx9pzhj 2940 12 minutes minute NNS cord-005646-xhx9pzhj 2940 13 ) ) -RRB- cord-005646-xhx9pzhj 2940 14 . . . cord-005646-xhx9pzhj 2941 1 The the DT cord-005646-xhx9pzhj 2941 2 phi phi NN cord-005646-xhx9pzhj 2941 3 was be VBD cord-005646-xhx9pzhj 2941 4 derived derive VBN cord-005646-xhx9pzhj 2941 5 from from IN cord-005646-xhx9pzhj 2941 6 application application NN cord-005646-xhx9pzhj 2941 7 of of IN cord-005646-xhx9pzhj 2941 8 the the DT cord-005646-xhx9pzhj 2941 9 Henderson Henderson NNP cord-005646-xhx9pzhj 2941 10 - - HYPH cord-005646-xhx9pzhj 2941 11 Hassdbach Hassdbach NNP cord-005646-xhx9pzhj 2941 12 formula formula NN cord-005646-xhx9pzhj 2941 13 using use VBG cord-005646-xhx9pzhj 2941 14 the the DT cord-005646-xhx9pzhj 2941 15 pCO2 pCO2 NNP cord-005646-xhx9pzhj 2941 16 value value NN cord-005646-xhx9pzhj 2941 17 from from IN cord-005646-xhx9pzhj 2941 18 the the DT cord-005646-xhx9pzhj 2941 19 tonometer tonometer NN cord-005646-xhx9pzhj 2941 20 and and CC cord-005646-xhx9pzhj 2941 21 the the DT cord-005646-xhx9pzhj 2941 22 arterial arterial JJ cord-005646-xhx9pzhj 2941 23 bic bic NNP cord-005646-xhx9pzhj 2941 24 ~ ~ NNP cord-005646-xhx9pzhj 2941 25 rbonate rbonate NNP cord-005646-xhx9pzhj 2941 26 . . . cord-005646-xhx9pzhj 2942 1 All all DT cord-005646-xhx9pzhj 2942 2 pipets pipet NNS cord-005646-xhx9pzhj 2942 3 received receive VBD cord-005646-xhx9pzhj 2942 4 raaitidiila raaitidiila NN cord-005646-xhx9pzhj 2942 5 before before IN cord-005646-xhx9pzhj 2942 6 sttrgery sttrgery NN cord-005646-xhx9pzhj 2942 7 . . . cord-005646-xhx9pzhj 2943 1 Values value NNS cord-005646-xhx9pzhj 2943 2 of of IN cord-005646-xhx9pzhj 2943 3 pHi pHi NNS cord-005646-xhx9pzhj 2943 4 above above IN cord-005646-xhx9pzhj 2943 5 7,35 7,35 CD cord-005646-xhx9pzhj 2943 6 and and CC cord-005646-xhx9pzhj 2943 7 lactate lactate NN cord-005646-xhx9pzhj 2943 8 levels level NNS cord-005646-xhx9pzhj 2943 9 between between IN cord-005646-xhx9pzhj 2944 1 6 6 CD cord-005646-xhx9pzhj 2944 2 and and CC cord-005646-xhx9pzhj 2944 3 15 15 CD cord-005646-xhx9pzhj 2944 4 mg mg NNP cord-005646-xhx9pzhj 2944 5 / / SYM cord-005646-xhx9pzhj 2944 6 dl dl NNP cord-005646-xhx9pzhj 2944 7 were be VBD cord-005646-xhx9pzhj 2944 8 considered consider VBN cord-005646-xhx9pzhj 2944 9 nortrM. nortrM. NNS cord-005646-xhx9pzhj 2945 1 The the DT cord-005646-xhx9pzhj 2945 2 results result NNS cord-005646-xhx9pzhj 2945 3 were be VBD cord-005646-xhx9pzhj 2945 4 statistically statistically RB cord-005646-xhx9pzhj 2945 5 anaJ.izated anaj.izate VBN cord-005646-xhx9pzhj 2945 6 with with IN cord-005646-xhx9pzhj 2945 7 ANOVA ANOVA NNP cord-005646-xhx9pzhj 2945 8 and and CC cord-005646-xhx9pzhj 2945 9 Bonferroni Bonferroni NNP cord-005646-xhx9pzhj 2945 10 tests test VBZ cord-005646-xhx9pzhj 2945 11 . . . cord-005646-xhx9pzhj 2946 1 Results result NNS cord-005646-xhx9pzhj 2946 2 : : : cord-005646-xhx9pzhj 2947 1 The the DT cord-005646-xhx9pzhj 2947 2 phi phi NN cord-005646-xhx9pzhj 2947 3 was be VBD cord-005646-xhx9pzhj 2947 4 normal normal JJ cord-005646-xhx9pzhj 2947 5 on on IN cord-005646-xhx9pzhj 2947 6 pre pre JJ cord-005646-xhx9pzhj 2947 7 anhepatic anhepatic JJ cord-005646-xhx9pzhj 2947 8 stage stage NN cord-005646-xhx9pzhj 2947 9 ( ( -LRB- cord-005646-xhx9pzhj 2947 10 > > NFP cord-005646-xhx9pzhj 2947 11 7,35 7,35 CD cord-005646-xhx9pzhj 2947 12 ) ) -RRB- cord-005646-xhx9pzhj 2947 13 and and CC cord-005646-xhx9pzhj 2947 14 lactate lactate NN cord-005646-xhx9pzhj 2947 15 levels level NNS cord-005646-xhx9pzhj 2947 16 were be VBD cord-005646-xhx9pzhj 2947 17 slightly slightly RB cord-005646-xhx9pzhj 2947 18 increased increase VBN cord-005646-xhx9pzhj 2947 19 ( ( -LRB- cord-005646-xhx9pzhj 2947 20 21 21 CD cord-005646-xhx9pzhj 2947 21 , , , cord-005646-xhx9pzhj 2947 22 5 5 CD cord-005646-xhx9pzhj 2947 23 + + CC cord-005646-xhx9pzhj 2947 24 _ _ NN cord-005646-xhx9pzhj 2947 25 8 8 CD cord-005646-xhx9pzhj 2947 26 , , , cord-005646-xhx9pzhj 2947 27 9 9 CD cord-005646-xhx9pzhj 2947 28 and and CC cord-005646-xhx9pzhj 2947 29 19 19 CD cord-005646-xhx9pzhj 2947 30 , , , cord-005646-xhx9pzhj 2947 31 5 5 CD cord-005646-xhx9pzhj 2947 32 ±5 ±5 NNS cord-005646-xhx9pzhj 2947 33 , , , cord-005646-xhx9pzhj 2947 34 9mg 9mg NN cord-005646-xhx9pzhj 2947 35 / / SYM cord-005646-xhx9pzhj 2947 36 dL dl NN cord-005646-xhx9pzhj 2947 37 NS NS NNP cord-005646-xhx9pzhj 2947 38 ) ) -RRB- cord-005646-xhx9pzhj 2947 39 . . . cord-005646-xhx9pzhj 2948 1 In in IN cord-005646-xhx9pzhj 2948 2 relalion relalion NN cord-005646-xhx9pzhj 2948 3 to to IN cord-005646-xhx9pzhj 2948 4 we -PRON- PRP cord-005646-xhx9pzhj 2948 5 - - HYPH cord-005646-xhx9pzhj 2948 6 anhepatics anhepatic NNS cord-005646-xhx9pzhj 2948 7 values value NNS cord-005646-xhx9pzhj 2948 8 , , , cord-005646-xhx9pzhj 2948 9 pHi pHi NNS cord-005646-xhx9pzhj 2948 10 decreased decrease VBD cord-005646-xhx9pzhj 2948 11 signNcatly signncatly RB cord-005646-xhx9pzhj 2948 12 at at IN cord-005646-xhx9pzhj 2948 13 the the DT cord-005646-xhx9pzhj 2948 14 mid mid NN cord-005646-xhx9pzhj 2948 15 of of IN cord-005646-xhx9pzhj 2948 16 anhevatic anhevatic JJ cord-005646-xhx9pzhj 2948 17 stage stage NN cord-005646-xhx9pzhj 2949 1 ( ( -LRB- cord-005646-xhx9pzhj 2949 2 7,39_+0,14 7,39_+0,14 NNP cord-005646-xhx9pzhj 2949 3 vs vs IN cord-005646-xhx9pzhj 2949 4 6,94_+0,1 6,94_+0,1 CD cord-005646-xhx9pzhj 2949 5 p<0,001 p<0,001 NNP cord-005646-xhx9pzhj 2949 6 ) ) -RRB- cord-005646-xhx9pzhj 2949 7 , , , cord-005646-xhx9pzhj 2949 8 phi phi NNP cord-005646-xhx9pzhj 2949 9 remain remain VBP cord-005646-xhx9pzhj 2949 10 low low JJ cord-005646-xhx9pzhj 2949 11 in in IN cord-005646-xhx9pzhj 2949 12 stage stage NN cord-005646-xhx9pzhj 2949 13 III III NNP cord-005646-xhx9pzhj 2949 14 , , , cord-005646-xhx9pzhj 2949 15 at at IN cord-005646-xhx9pzhj 2949 16 30 30 CD cord-005646-xhx9pzhj 2949 17 rain rain NN cord-005646-xhx9pzhj 2949 18 ( ( -LRB- cord-005646-xhx9pzhj 2949 19 6,86 6,86 NN cord-005646-xhx9pzhj 2949 20 + + SYM cord-005646-xhx9pzhj 2949 21 0,12 0,12 CD cord-005646-xhx9pzhj 2949 22 p p NN cord-005646-xhx9pzhj 2949 23 < < XX cord-005646-xhx9pzhj 2949 24 0,001 0,001 CD cord-005646-xhx9pzhj 2949 25 ) ) -RRB- cord-005646-xhx9pzhj 2949 26 and and CC cord-005646-xhx9pzhj 2949 27 90 90 CD cord-005646-xhx9pzhj 2949 28 min(G94-+O min(G94-+O NNP cord-005646-xhx9pzhj 2949 29 , , , cord-005646-xhx9pzhj 2949 30 12 12 CD cord-005646-xhx9pzhj 2949 31 p p NN cord-005646-xhx9pzhj 2949 32 < < XX cord-005646-xhx9pzhj 2949 33 0,001 0,001 CD cord-005646-xhx9pzhj 2949 34 ) ) -RRB- cord-005646-xhx9pzhj 2949 35 . . . cord-005646-xhx9pzhj 2950 1 Arterial arterial JJ cord-005646-xhx9pzhj 2950 2 lactate lactate NN cord-005646-xhx9pzhj 2950 3 levels level NNS cord-005646-xhx9pzhj 2950 4 increased increase VBD cord-005646-xhx9pzhj 2950 5 significatly significatly RB cord-005646-xhx9pzhj 2950 6 in in IN cord-005646-xhx9pzhj 2950 7 relation relation NN cord-005646-xhx9pzhj 2950 8 to to IN cord-005646-xhx9pzhj 2950 9 levels level NNS cord-005646-xhx9pzhj 2950 10 in in IN cord-005646-xhx9pzhj 2950 11 stage stage NN cord-005646-xhx9pzhj 2951 1 I -PRON- PRP cord-005646-xhx9pzhj 2951 2 , , , cord-005646-xhx9pzhj 2951 3 at at IN cord-005646-xhx9pzhj 2951 4 30 30 CD cord-005646-xhx9pzhj 2951 5 rain rain NN cord-005646-xhx9pzhj 2951 6 ( ( -LRB- cord-005646-xhx9pzhj 2951 7 63,6_+9,7 63,6_+9,7 CD cord-005646-xhx9pzhj 2951 8 p<0,O01 p<0,o01 JJ cord-005646-xhx9pzhj 2951 9 ) ) -RRB- cord-005646-xhx9pzhj 2951 10 arid arid JJ cord-005646-xhx9pzhj 2951 11 90 90 CD cord-005646-xhx9pzhj 2951 12 rain rain NN cord-005646-xhx9pzhj 2951 13 ( ( -LRB- cord-005646-xhx9pzhj 2951 14 65,8±9,9 65,8±9,9 NNP cord-005646-xhx9pzhj 2951 15 p<0,001 p<0,001 NNP cord-005646-xhx9pzhj 2951 16 ) ) -RRB- cord-005646-xhx9pzhj 2951 17 of of IN cord-005646-xhx9pzhj 2951 18 reperfusion reperfusion NN cord-005646-xhx9pzhj 2951 19 stage stage NN cord-005646-xhx9pzhj 2951 20 . . . cord-005646-xhx9pzhj 2952 1 There there EX cord-005646-xhx9pzhj 2952 2 is be VBZ cord-005646-xhx9pzhj 2952 3 a a DT cord-005646-xhx9pzhj 2952 4 slight slight JJ cord-005646-xhx9pzhj 2952 5 improvement improvement NN cord-005646-xhx9pzhj 2952 6 on on IN cord-005646-xhx9pzhj 2952 7 phi phi NNP cord-005646-xhx9pzhj 2952 8 and and CC cord-005646-xhx9pzhj 2952 9 lactate lactate NNP cord-005646-xhx9pzhj 2952 10 Ievels Ievels NNP cord-005646-xhx9pzhj 2952 11 at at IN cord-005646-xhx9pzhj 2952 12 120 120 CD cord-005646-xhx9pzhj 2952 13 and and CC cord-005646-xhx9pzhj 2952 14 t80 t80 NN cord-005646-xhx9pzhj 2952 15 rain rain NN cord-005646-xhx9pzhj 2952 16 althought althought VBP cord-005646-xhx9pzhj 2952 17 the the DT cord-005646-xhx9pzhj 2952 18 differences difference NNS cord-005646-xhx9pzhj 2952 19 did do VBD cord-005646-xhx9pzhj 2952 20 not not RB cord-005646-xhx9pzhj 2952 21 reach reach VB cord-005646-xhx9pzhj 2952 22 significance significance NN cord-005646-xhx9pzhj 2952 23 . . . cord-005646-xhx9pzhj 2953 1 Cnmments cnmment NNS cord-005646-xhx9pzhj 2953 2 : : : cord-005646-xhx9pzhj 2953 3 phi phi NN cord-005646-xhx9pzhj 2953 4 and and CC cord-005646-xhx9pzhj 2953 5 arterial arterial JJ cord-005646-xhx9pzhj 2953 6 lactate lactate NN cord-005646-xhx9pzhj 2953 7 levels level NNS cord-005646-xhx9pzhj 2953 8 propperly propperly RB cord-005646-xhx9pzhj 2953 9 reflect reflect VBP cord-005646-xhx9pzhj 2953 10 hypoperfusion hypoperfusion NN cord-005646-xhx9pzhj 2953 11 on on IN cord-005646-xhx9pzhj 2953 12 the the DT cord-005646-xhx9pzhj 2953 13 experimental experimental JJ cord-005646-xhx9pzhj 2953 14 model model NN cord-005646-xhx9pzhj 2953 15 of of IN cord-005646-xhx9pzhj 2953 16 acute acute JJ cord-005646-xhx9pzhj 2953 17 intestinal intestinal JJ cord-005646-xhx9pzhj 2953 18 isdlemia isdlemia NN cord-005646-xhx9pzhj 2953 19 . . . cord-005646-xhx9pzhj 2954 1 B B NNP cord-005646-xhx9pzhj 2954 2 ~ ~ NFP cord-005646-xhx9pzhj 2954 3 kground kground NN cord-005646-xhx9pzhj 2954 4 : : : cord-005646-xhx9pzhj 2955 1 The the DT cord-005646-xhx9pzhj 2955 2 paediatrie paediatrie NN cord-005646-xhx9pzhj 2955 3 gallbladder gallbladder NN cord-005646-xhx9pzhj 2955 4 diseases disease NNS cord-005646-xhx9pzhj 2955 5 generally generally RB cord-005646-xhx9pzhj 2955 6 described describe VBN cord-005646-xhx9pzhj 2955 7 are be VBP cord-005646-xhx9pzhj 2955 8 calculous calculous JJ cord-005646-xhx9pzhj 2955 9 ¢hol ¢hol VBN cord-005646-xhx9pzhj 2955 10 ~ ~ NFP cord-005646-xhx9pzhj 2955 11 Tstitis Tstitis NNP cord-005646-xhx9pzhj 2955 12 , , , cord-005646-xhx9pzhj 2955 13 cystic cystic JJ cord-005646-xhx9pzhj 2955 14 duct duct NN cord-005646-xhx9pzhj 2955 15 obstruction obstruction NN cord-005646-xhx9pzhj 2955 16 , , , cord-005646-xhx9pzhj 2955 17 congenital congenital JJ cord-005646-xhx9pzhj 2955 18 anomaly anomaly NN cord-005646-xhx9pzhj 2955 19 of of IN cord-005646-xhx9pzhj 2955 20 the the DT cord-005646-xhx9pzhj 2955 21 biliary biliary JJ cord-005646-xhx9pzhj 2955 22 tract tract NN cord-005646-xhx9pzhj 2955 23 , , , cord-005646-xhx9pzhj 2955 24 and and CC cord-005646-xhx9pzhj 2955 25 inflammation inflammation NN cord-005646-xhx9pzhj 2955 26 . . . cord-005646-xhx9pzhj 2956 1 In in IN cord-005646-xhx9pzhj 2956 2 the the DT cord-005646-xhx9pzhj 2956 3 neonatal neonatal JJ cord-005646-xhx9pzhj 2956 4 period period NN cord-005646-xhx9pzhj 2956 5 , , , cord-005646-xhx9pzhj 2956 6 noulithogenie noulithogenie NNP cord-005646-xhx9pzhj 2956 7 gallbladder gallbladder NN cord-005646-xhx9pzhj 2956 8 disease disease NN cord-005646-xhx9pzhj 2956 9 could could MD cord-005646-xhx9pzhj 2956 10 be be VB cord-005646-xhx9pzhj 2956 11 also also RB cord-005646-xhx9pzhj 2956 12 due due JJ cord-005646-xhx9pzhj 2956 13 to to IN cord-005646-xhx9pzhj 2956 14 erythroblastosis erythroblastosis NN cord-005646-xhx9pzhj 2956 15 or or CC cord-005646-xhx9pzhj 2956 16 hyperalimentation hyperalimentation NN cord-005646-xhx9pzhj 2956 17 . . . cord-005646-xhx9pzhj 2957 1 Obieetive Obieetive NNP cord-005646-xhx9pzhj 2958 1 : : : cord-005646-xhx9pzhj 2958 2 We -PRON- PRP cord-005646-xhx9pzhj 2958 3 describe describe VBP cord-005646-xhx9pzhj 2958 4 an an DT cord-005646-xhx9pzhj 2958 5 other other JJ cord-005646-xhx9pzhj 2958 6 type type NN cord-005646-xhx9pzhj 2958 7 of of IN cord-005646-xhx9pzhj 2958 8 disease disease NN cord-005646-xhx9pzhj 2958 9 affecting affect VBG cord-005646-xhx9pzhj 2958 10 the the DT cord-005646-xhx9pzhj 2958 11 gallbladder gallbladder NN cord-005646-xhx9pzhj 2958 12 in in IN cord-005646-xhx9pzhj 2958 13 neonates neonate NNS cord-005646-xhx9pzhj 2958 14 thought think VBN cord-005646-xhx9pzhj 2958 15 to to TO cord-005646-xhx9pzhj 2958 16 be be VB cord-005646-xhx9pzhj 2958 17 related relate VBN cord-005646-xhx9pzhj 2958 18 to to IN cord-005646-xhx9pzhj 2958 19 their -PRON- PRP$ cord-005646-xhx9pzhj 2958 20 vascular vascular JJ cord-005646-xhx9pzhj 2958 21 vulnerability vulnerability NN cord-005646-xhx9pzhj 2958 22 . . . cord-005646-xhx9pzhj 2959 1 Methods method NNS cord-005646-xhx9pzhj 2959 2 : : : cord-005646-xhx9pzhj 2959 3 Four four CD cord-005646-xhx9pzhj 2959 4 patients patient NNS cord-005646-xhx9pzhj 2959 5 with with IN cord-005646-xhx9pzhj 2959 6 abnormal abnormal JJ cord-005646-xhx9pzhj 2959 7 gallbladder gallbladder NN cord-005646-xhx9pzhj 2959 8 ultrasound ultrasound NN cord-005646-xhx9pzhj 2959 9 not not RB cord-005646-xhx9pzhj 2959 10 related relate VBN cord-005646-xhx9pzhj 2959 11 to to IN cord-005646-xhx9pzhj 2959 12 classical classical JJ cord-005646-xhx9pzhj 2959 13 observations observation NNS cord-005646-xhx9pzhj 2959 14 were be VBD cord-005646-xhx9pzhj 2959 15 included include VBN cord-005646-xhx9pzhj 2959 16 . . . cord-005646-xhx9pzhj 2960 1 We -PRON- PRP cord-005646-xhx9pzhj 2960 2 have have VBP cord-005646-xhx9pzhj 2960 3 studied study VBN cord-005646-xhx9pzhj 2960 4 and and CC cord-005646-xhx9pzhj 2960 5 reviewed review VBD cord-005646-xhx9pzhj 2960 6 the the DT cord-005646-xhx9pzhj 2960 7 biological biological JJ cord-005646-xhx9pzhj 2960 8 and and CC cord-005646-xhx9pzhj 2960 9 clinical clinical JJ cord-005646-xhx9pzhj 2960 10 data datum NNS cord-005646-xhx9pzhj 2960 11 , , , cord-005646-xhx9pzhj 2960 12 the the DT cord-005646-xhx9pzhj 2960 13 ultrasound ultrasound NN cord-005646-xhx9pzhj 2960 14 findings finding NNS cord-005646-xhx9pzhj 2960 15 and and CC cord-005646-xhx9pzhj 2960 16 their -PRON- PRP$ cord-005646-xhx9pzhj 2960 17 evolutions evolution NNS cord-005646-xhx9pzhj 2960 18 . . . cord-005646-xhx9pzhj 2961 1 Results result NNS cord-005646-xhx9pzhj 2961 2 : : : cord-005646-xhx9pzhj 2962 1 Four four CD cord-005646-xhx9pzhj 2962 2 patients patient NNS cord-005646-xhx9pzhj 2962 3 , , , cord-005646-xhx9pzhj 2962 4 30 30 CD cord-005646-xhx9pzhj 2962 5 to to TO cord-005646-xhx9pzhj 2962 6 32 32 CD cord-005646-xhx9pzhj 2962 7 ~.k ~.k NNP cord-005646-xhx9pzhj 2962 8 - - HYPH cord-005646-xhx9pzhj 2962 9 old old JJ cord-005646-xhx9pzhj 2962 10 neonates neonate NNS cord-005646-xhx9pzhj 2962 11 ~ffth ~ffth NFP cord-005646-xhx9pzhj 2962 12 a a DT cord-005646-xhx9pzhj 2962 13 birthweight birthweight JJ cord-005646-xhx9pzhj 2962 14 be~,een be~,een NNP cord-005646-xhx9pzhj 2962 15 1,3 1,3 CD cord-005646-xhx9pzhj 2962 16 and and CC cord-005646-xhx9pzhj 2962 17 1,9 1,9 CD cord-005646-xhx9pzhj 2962 18 kg kg NNS cord-005646-xhx9pzhj 2962 19 , , , cord-005646-xhx9pzhj 2962 20 were be VBD cord-005646-xhx9pzhj 2962 21 intubated intubate VBN cord-005646-xhx9pzhj 2962 22 and and CC cord-005646-xhx9pzhj 2962 23 under under IN cord-005646-xhx9pzhj 2962 24 total total JJ cord-005646-xhx9pzhj 2962 25 parenteral parenteral JJ cord-005646-xhx9pzhj 2962 26 nutrition nutrition NN cord-005646-xhx9pzhj 2962 27 for for IN cord-005646-xhx9pzhj 2962 28 10 10 CD cord-005646-xhx9pzhj 2962 29 to to TO cord-005646-xhx9pzhj 2962 30 35 35 CD cord-005646-xhx9pzhj 2962 31 days day NNS cord-005646-xhx9pzhj 2962 32 . . . cord-005646-xhx9pzhj 2963 1 None none NN cord-005646-xhx9pzhj 2963 2 of of IN cord-005646-xhx9pzhj 2963 3 them -PRON- PRP cord-005646-xhx9pzhj 2963 4 were be VBD cord-005646-xhx9pzhj 2963 5 symptomatic symptomatic JJ cord-005646-xhx9pzhj 2963 6 on on IN cord-005646-xhx9pzhj 2963 7 repeated repeat VBN cord-005646-xhx9pzhj 2963 8 clinical clinical JJ cord-005646-xhx9pzhj 2963 9 evaluations evaluation NNS cord-005646-xhx9pzhj 2963 10 . . . cord-005646-xhx9pzhj 2964 1 One one CD cord-005646-xhx9pzhj 2964 2 newborn newborn NN cord-005646-xhx9pzhj 2964 3 developped developpe VBD cord-005646-xhx9pzhj 2964 4 hypotensien hypotensien NNP cord-005646-xhx9pzhj 2964 5 on on IN cord-005646-xhx9pzhj 2964 6 umbilical umbilical JJ cord-005646-xhx9pzhj 2964 7 bleeding bleeding NN cord-005646-xhx9pzhj 2964 8 at at IN cord-005646-xhx9pzhj 2964 9 3 3 CD cord-005646-xhx9pzhj 2964 10 hours hour NNS cord-005646-xhx9pzhj 2964 11 of of IN cord-005646-xhx9pzhj 2964 12 life life NN cord-005646-xhx9pzhj 2964 13 . . . cord-005646-xhx9pzhj 2965 1 In in IN cord-005646-xhx9pzhj 2965 2 two two CD cord-005646-xhx9pzhj 2965 3 cases case NNS cord-005646-xhx9pzhj 2965 4 , , , cord-005646-xhx9pzhj 2965 5 signs sign NNS cord-005646-xhx9pzhj 2965 6 of of IN cord-005646-xhx9pzhj 2965 7 cholestasis cholestasis NN cord-005646-xhx9pzhj 2965 8 were be VBD cord-005646-xhx9pzhj 2965 9 discovered discover VBN cord-005646-xhx9pzhj 2965 10 : : : cord-005646-xhx9pzhj 2965 11 the the DT cord-005646-xhx9pzhj 2965 12 total total JJ cord-005646-xhx9pzhj 2965 13 bilirubin bilirubin JJ cord-005646-xhx9pzhj 2965 14 level level NN cord-005646-xhx9pzhj 2965 15 has have VBZ cord-005646-xhx9pzhj 2965 16 risen rise VBN cord-005646-xhx9pzhj 2965 17 to to IN cord-005646-xhx9pzhj 2965 18 5 5 CD cord-005646-xhx9pzhj 2965 19 mg mg NNP cord-005646-xhx9pzhj 2965 20 / / SYM cord-005646-xhx9pzhj 2965 21 dl dl NNP cord-005646-xhx9pzhj 2965 22 ; ; : cord-005646-xhx9pzhj 2965 23 the the DT cord-005646-xhx9pzhj 2965 24 direct direct JJ cord-005646-xhx9pzhj 2965 25 bilirubin bilirubin NN cord-005646-xhx9pzhj 2965 26 level level NN cord-005646-xhx9pzhj 2965 27 was be VBD cord-005646-xhx9pzhj 2965 28 1,5 1,5 CD cord-005646-xhx9pzhj 2965 29 mg mg NNP cord-005646-xhx9pzhj 2965 30 / / SYM cord-005646-xhx9pzhj 2965 31 dl dl NNP cord-005646-xhx9pzhj 2965 32 while while IN cord-005646-xhx9pzhj 2965 33 the the DT cord-005646-xhx9pzhj 2965 34 urina urina NN cord-005646-xhx9pzhj 2965 35 were be VBD cord-005646-xhx9pzhj 2965 36 dark dark JJ cord-005646-xhx9pzhj 2965 37 and and CC cord-005646-xhx9pzhj 2965 38 the the DT cord-005646-xhx9pzhj 2965 39 ~o~,ls ~o~,ls JJ cord-005646-xhx9pzhj 2965 40 : : : cord-005646-xhx9pzhj 2965 41 mcolour~. mcolour~. NNP cord-005646-xhx9pzhj 2966 1 The the DT cord-005646-xhx9pzhj 2966 2 c c NN cord-005646-xhx9pzhj 2967 1 ~mplct~ ~mplct~ NNP cord-005646-xhx9pzhj 2967 2 ~crology ~crology NFP cord-005646-xhx9pzhj 2967 3 as as IN cord-005646-xhx9pzhj 2967 4 a a DT cord-005646-xhx9pzhj 2967 5 ! ! . cord-005646-xhx9pzhj 2967 6 ! ! . cord-005646-xhx9pzhj 2968 1 the the DT cord-005646-xhx9pzhj 2968 2 culVare~ culvare~ NN cord-005646-xhx9pzhj 2968 3 remained remain VBD cord-005646-xhx9pzhj 2968 4 negative negative JJ cord-005646-xhx9pzhj 2968 5 . . . cord-005646-xhx9pzhj 2969 1 The the DT cord-005646-xhx9pzhj 2969 2 ultrasound ultrasound NN cord-005646-xhx9pzhj 2969 3 explorations exploration NNS cord-005646-xhx9pzhj 2969 4 were be VBD cord-005646-xhx9pzhj 2969 5 atypical atypical JJ cord-005646-xhx9pzhj 2969 6 : : : cord-005646-xhx9pzhj 2969 7 in in IN cord-005646-xhx9pzhj 2969 8 the the DT cord-005646-xhx9pzhj 2969 9 four four CD cord-005646-xhx9pzhj 2969 10 eases ease VBZ cord-005646-xhx9pzhj 2969 11 , , , cord-005646-xhx9pzhj 2969 12 an an DT cord-005646-xhx9pzhj 2969 13 initial initial JJ cord-005646-xhx9pzhj 2969 14 increasing increase VBG cord-005646-xhx9pzhj 2969 15 broad broad JJ cord-005646-xhx9pzhj 2969 16 and and CC cord-005646-xhx9pzhj 2969 17 thickness thickness NN cord-005646-xhx9pzhj 2969 18 of of IN cord-005646-xhx9pzhj 2969 19 the the DT cord-005646-xhx9pzhj 2969 20 wall wall NN cord-005646-xhx9pzhj 2969 21 of of IN cord-005646-xhx9pzhj 2969 22 the the DT cord-005646-xhx9pzhj 2969 23 gallbladder gallbladder NN cord-005646-xhx9pzhj 2969 24 with with IN cord-005646-xhx9pzhj 2969 25 an an DT cord-005646-xhx9pzhj 2969 26 hyperecbogenie hyperecbogenie NN cord-005646-xhx9pzhj 2969 27 inside inside IN cord-005646-xhx9pzhj 2969 28 content content NN cord-005646-xhx9pzhj 2969 29 , , , cord-005646-xhx9pzhj 2969 30 which which WDT cord-005646-xhx9pzhj 2969 31 was be VBD cord-005646-xhx9pzhj 2969 32 not not RB cord-005646-xhx9pzhj 2969 33 sludge sludge NN cord-005646-xhx9pzhj 2969 34 , , , cord-005646-xhx9pzhj 2969 35 was be VBD cord-005646-xhx9pzhj 2969 36 discovered discover VBN cord-005646-xhx9pzhj 2969 37 . . . cord-005646-xhx9pzhj 2970 1 In in IN cord-005646-xhx9pzhj 2970 2 three three CD cord-005646-xhx9pzhj 2970 3 eases ease VBZ cord-005646-xhx9pzhj 2970 4 the the DT cord-005646-xhx9pzhj 2970 5 images image NNS cord-005646-xhx9pzhj 2970 6 resolved resolve VBN cord-005646-xhx9pzhj 2970 7 in in IN cord-005646-xhx9pzhj 2970 8 ten ten CD cord-005646-xhx9pzhj 2970 9 to to TO cord-005646-xhx9pzhj 2970 10 fifteen fifteen CD cord-005646-xhx9pzhj 2970 11 days day NNS cord-005646-xhx9pzhj 2970 12 . . . cord-005646-xhx9pzhj 2971 1 In in IN cord-005646-xhx9pzhj 2971 2 one one CD cord-005646-xhx9pzhj 2971 3 ease ease NN cord-005646-xhx9pzhj 2971 4 , , , cord-005646-xhx9pzhj 2971 5 an an DT cord-005646-xhx9pzhj 2971 6 asymptomatie asymptomatie NN cord-005646-xhx9pzhj 2971 7 thrombosis thrombosis NN cord-005646-xhx9pzhj 2971 8 of of IN cord-005646-xhx9pzhj 2971 9 the the DT cord-005646-xhx9pzhj 2971 10 vena vena NNP cord-005646-xhx9pzhj 2971 11 portu portu NNP cord-005646-xhx9pzhj 2971 12 which which WDT cord-005646-xhx9pzhj 2971 13 remained remain VBD cord-005646-xhx9pzhj 2971 14 patent patent NN cord-005646-xhx9pzhj 2971 15 was be VBD cord-005646-xhx9pzhj 2971 16 discovered discover VBN cord-005646-xhx9pzhj 2971 17 . . . cord-005646-xhx9pzhj 2972 1 In in IN cord-005646-xhx9pzhj 2972 2 this this DT cord-005646-xhx9pzhj 2972 3 case case NN cord-005646-xhx9pzhj 2972 4 , , , cord-005646-xhx9pzhj 2972 5 at at IN cord-005646-xhx9pzhj 2972 6 one one CD cord-005646-xhx9pzhj 2972 7 month month NN cord-005646-xhx9pzhj 2972 8 , , , cord-005646-xhx9pzhj 2972 9 the the DT cord-005646-xhx9pzhj 2972 10 ultrasound ultrasound NN cord-005646-xhx9pzhj 2972 11 showed show VBD cord-005646-xhx9pzhj 2972 12 images image NNS cord-005646-xhx9pzhj 2972 13 encountered encounter VBN cord-005646-xhx9pzhj 2972 14 in in IN cord-005646-xhx9pzhj 2972 15 chronic chronic JJ cord-005646-xhx9pzhj 2972 16 ebolecystitis ebolecystitis NN cord-005646-xhx9pzhj 2972 17 and and CC cord-005646-xhx9pzhj 2972 18 , , , cord-005646-xhx9pzhj 2972 19 at at IN cord-005646-xhx9pzhj 2972 20 one one CD cord-005646-xhx9pzhj 2972 21 year year NN cord-005646-xhx9pzhj 2972 22 , , , cord-005646-xhx9pzhj 2972 23 the the DT cord-005646-xhx9pzhj 2972 24 gallbladder gallbladder NN cord-005646-xhx9pzhj 2972 25 appeared appear VBD cord-005646-xhx9pzhj 2972 26 atrophic atrophic JJ cord-005646-xhx9pzhj 2972 27 . . . cord-005646-xhx9pzhj 2973 1 None none NN cord-005646-xhx9pzhj 2973 2 of of IN cord-005646-xhx9pzhj 2973 3 them -PRON- PRP cord-005646-xhx9pzhj 2973 4 underwent undergo VBD cord-005646-xhx9pzhj 2973 5 surgery surgery NN cord-005646-xhx9pzhj 2973 6 . . . cord-005646-xhx9pzhj 2974 1 Conelusiou Conelusiou NNP cord-005646-xhx9pzhj 2974 2 : : : cord-005646-xhx9pzhj 2975 1 The the DT cord-005646-xhx9pzhj 2975 2 gallbladder gallbladder NN cord-005646-xhx9pzhj 2975 3 diseases disease NNS cord-005646-xhx9pzhj 2975 4 are be VBP cord-005646-xhx9pzhj 2975 5 multifactorial multifactorial JJ cord-005646-xhx9pzhj 2975 6 . . . cord-005646-xhx9pzhj 2976 1 Besides besides IN cord-005646-xhx9pzhj 2976 2 the the DT cord-005646-xhx9pzhj 2976 3 prematurity prematurity NN cord-005646-xhx9pzhj 2976 4 , , , cord-005646-xhx9pzhj 2976 5 the the DT cord-005646-xhx9pzhj 2976 6 infections infection NNS cord-005646-xhx9pzhj 2976 7 , , , cord-005646-xhx9pzhj 2976 8 the the DT cord-005646-xhx9pzhj 2976 9 total total JJ cord-005646-xhx9pzhj 2976 10 parenteral parenteral JJ cord-005646-xhx9pzhj 2976 11 nutrition nutrition NN cord-005646-xhx9pzhj 2976 12 , , , cord-005646-xhx9pzhj 2976 13 the the DT cord-005646-xhx9pzhj 2976 14 premature premature JJ cord-005646-xhx9pzhj 2976 15 neonate neonate NN cord-005646-xhx9pzhj 2976 16 is be VBZ cord-005646-xhx9pzhj 2976 17 exposed expose VBN cord-005646-xhx9pzhj 2976 18 to to IN cord-005646-xhx9pzhj 2976 19 vascular vascular JJ cord-005646-xhx9pzhj 2976 20 vulnerability vulnerability NN cord-005646-xhx9pzhj 2976 21 affecting affect VBG cord-005646-xhx9pzhj 2976 22 also also RB cord-005646-xhx9pzhj 2976 23 the the DT cord-005646-xhx9pzhj 2976 24 gallbladder gallbladder NN cord-005646-xhx9pzhj 2976 25 and and CC cord-005646-xhx9pzhj 2976 26 this this DT cord-005646-xhx9pzhj 2976 27 may may MD cord-005646-xhx9pzhj 2976 28 explain explain VB cord-005646-xhx9pzhj 2976 29 our -PRON- PRP$ cord-005646-xhx9pzhj 2976 30 findings finding NNS cord-005646-xhx9pzhj 2976 31 . . . cord-005646-xhx9pzhj 2977 1 Progress progress VB cord-005646-xhx9pzhj 2977 2 in in IN cord-005646-xhx9pzhj 2977 3 prognosis prognosis NN cord-005646-xhx9pzhj 2977 4 of of IN cord-005646-xhx9pzhj 2977 5 pts pts NN cord-005646-xhx9pzhj 2977 6 with with IN cord-005646-xhx9pzhj 2977 7 B B NNP cord-005646-xhx9pzhj 2977 8 - - HYPH cord-005646-xhx9pzhj 2977 9 NHL NHL NNP cord-005646-xhx9pzhj 2977 10 had have VBD cord-005646-xhx9pzhj 2977 11 followed follow VBN cord-005646-xhx9pzhj 2977 12 the the DT cord-005646-xhx9pzhj 2977 13 use use NN cord-005646-xhx9pzhj 2977 14 of of IN cord-005646-xhx9pzhj 2977 15 multimodality multimodality NN cord-005646-xhx9pzhj 2977 16 chemotherapy chemotherapy NN cord-005646-xhx9pzhj 2977 17 ( ( -LRB- cord-005646-xhx9pzhj 2977 18 CT CT NNP cord-005646-xhx9pzhj 2977 19 ) ) -RRB- cord-005646-xhx9pzhj 2977 20 . . . cord-005646-xhx9pzhj 2978 1 With with IN cord-005646-xhx9pzhj 2978 2 the the DT cord-005646-xhx9pzhj 2978 3 prolonged prolong VBN cord-005646-xhx9pzhj 2978 4 survival survival NN cord-005646-xhx9pzhj 2978 5 , , , cord-005646-xhx9pzhj 2978 6 there there EX cord-005646-xhx9pzhj 2978 7 are be VBP cord-005646-xhx9pzhj 2978 8 comlications comlication NNS cord-005646-xhx9pzhj 2978 9 due due JJ cord-005646-xhx9pzhj 2978 10 to to IN cord-005646-xhx9pzhj 2978 11 myetosupression myetosupression NNP cord-005646-xhx9pzhj 2978 12 & & CC cord-005646-xhx9pzhj 2978 13 desease desease NNP cord-005646-xhx9pzhj 2978 14 process process NN cord-005646-xhx9pzhj 2978 15 . . . cord-005646-xhx9pzhj 2979 1 The the DT cord-005646-xhx9pzhj 2979 2 syndrome syndrome NN cord-005646-xhx9pzhj 2979 3 of of IN cord-005646-xhx9pzhj 2979 4 Neutropenic Neutropenic NNP cord-005646-xhx9pzhj 2979 5 Enterocolitis Enterocolitis NNP cord-005646-xhx9pzhj 2979 6 ( ( -LRB- cord-005646-xhx9pzhj 2979 7 NE NE NNP cord-005646-xhx9pzhj 2979 8 ) ) -RRB- cord-005646-xhx9pzhj 2979 9 is be VBZ cord-005646-xhx9pzhj 2979 10 one one CD cord-005646-xhx9pzhj 2979 11 of of IN cord-005646-xhx9pzhj 2979 12 the the DT cord-005646-xhx9pzhj 2979 13 ominous ominous JJ cord-005646-xhx9pzhj 2979 14 problems problem NNS cord-005646-xhx9pzhj 2979 15 because because IN cord-005646-xhx9pzhj 2979 16 ofpts ofpts JJ cord-005646-xhx9pzhj 2979 17 increased increase VBN cord-005646-xhx9pzhj 2979 18 susceptibility susceptibility NN cord-005646-xhx9pzhj 2979 19 to to IN cord-005646-xhx9pzhj 2979 20 infection infection NN cord-005646-xhx9pzhj 2979 21 & & CC cord-005646-xhx9pzhj 2979 22 overwhelming overwhelming JJ cord-005646-xhx9pzhj 2979 23 sepsis sepsis NN cord-005646-xhx9pzhj 2979 24 . . . cord-005646-xhx9pzhj 2980 1 This this DT cord-005646-xhx9pzhj 2980 2 material material NN cord-005646-xhx9pzhj 2980 3 included include VBD cord-005646-xhx9pzhj 2980 4 25 25 CD cord-005646-xhx9pzhj 2980 5 neutropenic neutropenic JJ cord-005646-xhx9pzhj 2980 6 pts pt NNS cord-005646-xhx9pzhj 2980 7 ( ( -LRB- cord-005646-xhx9pzhj 2980 8 4 4 CD cord-005646-xhx9pzhj 2980 9 - - SYM cord-005646-xhx9pzhj 2980 10 14 14 CD cord-005646-xhx9pzhj 2980 11 years year NNS cord-005646-xhx9pzhj 2980 12 ) ) -RRB- cord-005646-xhx9pzhj 2980 13 with with IN cord-005646-xhx9pzhj 2980 14 the the DT cord-005646-xhx9pzhj 2980 15 stages stage NNS cord-005646-xhx9pzhj 2980 16 IIl IIl NNPS cord-005646-xhx9pzhj 2980 17 & & CC cord-005646-xhx9pzhj 2980 18 IV IV NNP cord-005646-xhx9pzhj 2980 19 of of IN cord-005646-xhx9pzhj 2980 20 B B NNP cord-005646-xhx9pzhj 2980 21 - - HYPH cord-005646-xhx9pzhj 2980 22 NHL NHL NNP cord-005646-xhx9pzhj 2980 23 who who WP cord-005646-xhx9pzhj 2980 24 were be VBD cord-005646-xhx9pzhj 2980 25 treated treat VBN cord-005646-xhx9pzhj 2980 26 with with IN cord-005646-xhx9pzhj 2980 27 the the DT cord-005646-xhx9pzhj 2980 28 modifired modifired JJ cord-005646-xhx9pzhj 2980 29 BFM-90 BFM-90 NNP cord-005646-xhx9pzhj 2981 1 ( ( -LRB- cord-005646-xhx9pzhj 2981 2 MTX MTX NNP cord-005646-xhx9pzhj 2981 3 1 1 CD cord-005646-xhx9pzhj 2981 4 g g NNP cord-005646-xhx9pzhj 2981 5 / / SYM cord-005646-xhx9pzhj 2981 6 m m NNP cord-005646-xhx9pzhj 2981 7 2 2 CD cord-005646-xhx9pzhj 2981 8 in in IN cord-005646-xhx9pzhj 2981 9 24-h 24-h JJ cord-005646-xhx9pzhj 2981 10 inf inf NN cord-005646-xhx9pzhj 2981 11 . . . cord-005646-xhx9pzhj 2981 12 ) ) -RRB- cord-005646-xhx9pzhj 2981 13 ; ; : cord-005646-xhx9pzhj 2981 14 22 22 CD cord-005646-xhx9pzhj 2981 15 males male NNS cord-005646-xhx9pzhj 2981 16 , , , cord-005646-xhx9pzhj 2981 17 3 3 CD cord-005646-xhx9pzhj 2981 18 females female NNS cord-005646-xhx9pzhj 2981 19 . . . cord-005646-xhx9pzhj 2982 1 Seventeen seventeen CD cord-005646-xhx9pzhj 2982 2 episodes episode NNS cord-005646-xhx9pzhj 2982 3 of of IN cord-005646-xhx9pzhj 2982 4 NE NE NNP cord-005646-xhx9pzhj 2982 5 were be VBD cord-005646-xhx9pzhj 2982 6 observed observe VBN cord-005646-xhx9pzhj 2982 7 & & CC cord-005646-xhx9pzhj 2982 8 only only RB cord-005646-xhx9pzhj 2982 9 after after IN cord-005646-xhx9pzhj 2982 10 the the DT cord-005646-xhx9pzhj 2982 11 first first JJ cord-005646-xhx9pzhj 2982 12 2 2 CD cord-005646-xhx9pzhj 2982 13 courses course NNS cord-005646-xhx9pzhj 2982 14 of of IN cord-005646-xhx9pzhj 2982 15 CT CT NNP cord-005646-xhx9pzhj 2982 16 ( ( -LRB- cord-005646-xhx9pzhj 2982 17 13 13 CD cord-005646-xhx9pzhj 2982 18 of of IN cord-005646-xhx9pzhj 2982 19 25 25 CD cord-005646-xhx9pzhj 2982 20 after after IN cord-005646-xhx9pzhj 2982 21 tst tst NNP cord-005646-xhx9pzhj 2982 22 , , , cord-005646-xhx9pzhj 2982 23 53 53 CD cord-005646-xhx9pzhj 2982 24 % % NN cord-005646-xhx9pzhj 2982 25 ; ; : cord-005646-xhx9pzhj 2982 26 4 4 CD cord-005646-xhx9pzhj 2982 27 of of IN cord-005646-xhx9pzhj 2982 28 24 24 CD cord-005646-xhx9pzhj 2982 29 after after IN cord-005646-xhx9pzhj 2982 30 2nd 2nd JJ cord-005646-xhx9pzhj 2982 31 , , , cord-005646-xhx9pzhj 2982 32 17 17 CD cord-005646-xhx9pzhj 2982 33 % % NN cord-005646-xhx9pzhj 2982 34 ) ) -RRB- cord-005646-xhx9pzhj 2982 35 . . . cord-005646-xhx9pzhj 2983 1 The the DT cord-005646-xhx9pzhj 2983 2 symptoms symptom NNS cord-005646-xhx9pzhj 2983 3 existed exist VBD cord-005646-xhx9pzhj 2983 4 3 3 CD cord-005646-xhx9pzhj 2983 5 to to TO cord-005646-xhx9pzhj 2983 6 14 14 CD cord-005646-xhx9pzhj 2983 7 days day NNS cord-005646-xhx9pzhj 2983 8 . . . cord-005646-xhx9pzhj 2984 1 WBC WBC NNP cord-005646-xhx9pzhj 2984 2 ranged range VBD cord-005646-xhx9pzhj 2984 3 from from IN cord-005646-xhx9pzhj 2984 4 50 50 CD cord-005646-xhx9pzhj 2984 5 to to IN cord-005646-xhx9pzhj 2984 6 600 600 CD cord-005646-xhx9pzhj 2984 7 in in IN cord-005646-xhx9pzhj 2984 8 l l NNP cord-005646-xhx9pzhj 2984 9 ~ ~ NFP cord-005646-xhx9pzhj 2984 10 tl tl NNP cord-005646-xhx9pzhj 2984 11 ( ( -LRB- cord-005646-xhx9pzhj 2984 12 median median NN cord-005646-xhx9pzhj 2984 13 , , , cord-005646-xhx9pzhj 2984 14 100 100 CD cord-005646-xhx9pzhj 2984 15 ) ) -RRB- cord-005646-xhx9pzhj 2984 16 . . . cord-005646-xhx9pzhj 2985 1 The the DT cord-005646-xhx9pzhj 2985 2 first first JJ cord-005646-xhx9pzhj 2985 3 signs sign NNS cord-005646-xhx9pzhj 2985 4 of of IN cord-005646-xhx9pzhj 2985 5 NE NE NNP cord-005646-xhx9pzhj 2985 6 were be VBD cord-005646-xhx9pzhj 2985 7 directly directly RB cord-005646-xhx9pzhj 2985 8 correlated correlate VBN cord-005646-xhx9pzhj 2985 9 to to IN cord-005646-xhx9pzhj 2985 10 the the DT cord-005646-xhx9pzhj 2985 11 beginning beginning NN cord-005646-xhx9pzhj 2985 12 of of IN cord-005646-xhx9pzhj 2985 13 the the DT cord-005646-xhx9pzhj 2985 14 neutropenia neutropenia NN cord-005646-xhx9pzhj 2985 15 & & CC cord-005646-xhx9pzhj 2985 16 the the DT cord-005646-xhx9pzhj 2985 17 recovery recovery NN cord-005646-xhx9pzhj 2985 18 of of IN cord-005646-xhx9pzhj 2985 19 neutrophils neutrophil NNS cord-005646-xhx9pzhj 2985 20 led lead VBD cord-005646-xhx9pzhj 2985 21 to to IN cord-005646-xhx9pzhj 2985 22 the the DT cord-005646-xhx9pzhj 2985 23 disappearance disappearance NN cord-005646-xhx9pzhj 2985 24 of of IN cord-005646-xhx9pzhj 2985 25 abdominal abdominal JJ cord-005646-xhx9pzhj 2985 26 recovery recovery NN cord-005646-xhx9pzhj 2985 27 of of IN cord-005646-xhx9pzhj 2985 28 neutrophils neutrophil NNS cord-005646-xhx9pzhj 2985 29 led lead VBD cord-005646-xhx9pzhj 2985 30 to to IN cord-005646-xhx9pzhj 2985 31 the the DT cord-005646-xhx9pzhj 2985 32 disappearance disappearance NN cord-005646-xhx9pzhj 2985 33 of of IN cord-005646-xhx9pzhj 2985 34 abdominal abdominal JJ cord-005646-xhx9pzhj 2985 35 pain pain NN cord-005646-xhx9pzhj 2985 36 . . . cord-005646-xhx9pzhj 2986 1 The the DT cord-005646-xhx9pzhj 2986 2 conservative conservative JJ cord-005646-xhx9pzhj 2986 3 treatment treatment NN cord-005646-xhx9pzhj 2986 4 included include VBD cord-005646-xhx9pzhj 2986 5 gastrointestinal gastrointestinal JJ cord-005646-xhx9pzhj 2986 6 tract tract NN cord-005646-xhx9pzhj 2986 7 decompression decompression NN cord-005646-xhx9pzhj 2986 8 , , , cord-005646-xhx9pzhj 2986 9 broad broad JJ cord-005646-xhx9pzhj 2986 10 spectrum spectrum NN cord-005646-xhx9pzhj 2986 11 antibiotics antibiotic NNS cord-005646-xhx9pzhj 2986 12 initially initially RB cord-005646-xhx9pzhj 2986 13 , , , cord-005646-xhx9pzhj 2986 14 volume volume NN cord-005646-xhx9pzhj 2986 15 & & CC cord-005646-xhx9pzhj 2986 16 electrolyte electrolyte NN cord-005646-xhx9pzhj 2986 17 substitution substitution NN cord-005646-xhx9pzhj 2986 18 , , , cord-005646-xhx9pzhj 2986 19 nutritional nutritional JJ cord-005646-xhx9pzhj 2986 20 support support NN cord-005646-xhx9pzhj 2986 21 , , , cord-005646-xhx9pzhj 2986 22 correction correction NN cord-005646-xhx9pzhj 2986 23 of of IN cord-005646-xhx9pzhj 2986 24 acid acid NN cord-005646-xhx9pzhj 2986 25 - - HYPH cord-005646-xhx9pzhj 2986 26 base base NN cord-005646-xhx9pzhj 2986 27 balance balance NN cord-005646-xhx9pzhj 2986 28 , , , cord-005646-xhx9pzhj 2986 29 symptomatic symptomatic JJ cord-005646-xhx9pzhj 2986 30 treatment treatment NN cord-005646-xhx9pzhj 2986 31 . . . cord-005646-xhx9pzhj 2987 1 Sixteen sixteen CD cord-005646-xhx9pzhj 2987 2 pts pt NNS cord-005646-xhx9pzhj 2987 3 were be VBD cord-005646-xhx9pzhj 2987 4 treated treat VBN cord-005646-xhx9pzhj 2987 5 nonoperatively nonoperatively RB cord-005646-xhx9pzhj 2987 6 , , , cord-005646-xhx9pzhj 2987 7 1 1 CD cord-005646-xhx9pzhj 2987 8 died die VBD cord-005646-xhx9pzhj 2987 9 . . . cord-005646-xhx9pzhj 2988 1 On on IN cord-005646-xhx9pzhj 2988 2 autopsy autopsy JJ cord-005646-xhx9pzhj 2988 3 the the DT cord-005646-xhx9pzhj 2988 4 transmural transmural JJ cord-005646-xhx9pzhj 2988 5 bowel bowel NN cord-005646-xhx9pzhj 2988 6 necrosis necrosis NN cord-005646-xhx9pzhj 2988 7 due due IN cord-005646-xhx9pzhj 2988 8 to to IN cord-005646-xhx9pzhj 2988 9 thrombosis thrombosis NN cord-005646-xhx9pzhj 2988 10 of of IN cord-005646-xhx9pzhj 2988 11 branches branch NNS cord-005646-xhx9pzhj 2988 12 of of IN cord-005646-xhx9pzhj 2988 13 a.mes.sup a.mes.sup NNP cord-005646-xhx9pzhj 2988 14 , , , cord-005646-xhx9pzhj 2988 15 was be VBD cord-005646-xhx9pzhj 2988 16 found find VBN cord-005646-xhx9pzhj 2988 17 . . . cord-005646-xhx9pzhj 2989 1 The the DT cord-005646-xhx9pzhj 2989 2 bowel bowel NN cord-005646-xhx9pzhj 2989 3 perforation perforation NN cord-005646-xhx9pzhj 2989 4 occurred occur VBD cord-005646-xhx9pzhj 2989 5 in in IN cord-005646-xhx9pzhj 2989 6 one one CD cord-005646-xhx9pzhj 2989 7 patient patient NN cord-005646-xhx9pzhj 2989 8 , , , cord-005646-xhx9pzhj 2989 9 he -PRON- PRP cord-005646-xhx9pzhj 2989 10 was be VBD cord-005646-xhx9pzhj 2989 11 undergone undergo VBN cord-005646-xhx9pzhj 2989 12 laparotomy laparotomy NNP cord-005646-xhx9pzhj 2989 13 & & CC cord-005646-xhx9pzhj 2989 14 hemicolonectomy hemicolonectomy NNP cord-005646-xhx9pzhj 2989 15 & & CC cord-005646-xhx9pzhj 2989 16 survived survive VBD cord-005646-xhx9pzhj 2989 17 . . . cord-005646-xhx9pzhj 2990 1 We -PRON- PRP cord-005646-xhx9pzhj 2990 2 conclude conclude VBP cord-005646-xhx9pzhj 2990 3 that that IN cord-005646-xhx9pzhj 2990 4 NE NE NNP cord-005646-xhx9pzhj 2990 5 is be VBZ cord-005646-xhx9pzhj 2990 6 a a DT cord-005646-xhx9pzhj 2990 7 frequent frequent JJ cord-005646-xhx9pzhj 2990 8 complication complication NN cord-005646-xhx9pzhj 2990 9 in in IN cord-005646-xhx9pzhj 2990 10 neutropenic neutropenic JJ cord-005646-xhx9pzhj 2990 11 pts pt NNS cord-005646-xhx9pzhj 2990 12 with with IN cord-005646-xhx9pzhj 2990 13 the the DT cord-005646-xhx9pzhj 2990 14 st st NNP cord-005646-xhx9pzhj 2990 15 . . NNP cord-005646-xhx9pzhj 2990 16 lII lII NNP cord-005646-xhx9pzhj 2990 17 & & CC cord-005646-xhx9pzhj 2990 18 IV IV NNP cord-005646-xhx9pzhj 2990 19 of of IN cord-005646-xhx9pzhj 2990 20 B B NNP cord-005646-xhx9pzhj 2990 21 - - HYPH cord-005646-xhx9pzhj 2990 22 NHL NHL NNP cord-005646-xhx9pzhj 2990 23 . . . cord-005646-xhx9pzhj 2991 1 It -PRON- PRP cord-005646-xhx9pzhj 2991 2 occurs occur VBZ cord-005646-xhx9pzhj 2991 3 after after IN cord-005646-xhx9pzhj 2991 4 the the DT cord-005646-xhx9pzhj 2991 5 induction induction NN cord-005646-xhx9pzhj 2991 6 courses course NNS cord-005646-xhx9pzhj 2991 7 of of IN cord-005646-xhx9pzhj 2991 8 CT CT NNP cord-005646-xhx9pzhj 2991 9 . . . cord-005646-xhx9pzhj 2992 1 Close close JJ cord-005646-xhx9pzhj 2992 2 observation observation NN cord-005646-xhx9pzhj 2992 3 by by IN cord-005646-xhx9pzhj 2992 4 surgeons surgeon NNS cord-005646-xhx9pzhj 2992 5 , , , cord-005646-xhx9pzhj 2992 6 oncologists oncologist NNS cord-005646-xhx9pzhj 2992 7 & & CC cord-005646-xhx9pzhj 2992 8 pediatric pediatric JJ cord-005646-xhx9pzhj 2992 9 intensivists intensivists NNP cord-005646-xhx9pzhj 2992 10 is be VBZ cord-005646-xhx9pzhj 2992 11 mandatory mandatory JJ cord-005646-xhx9pzhj 2992 12 . . . cord-005646-xhx9pzhj 2993 1 Conservative conservative JJ cord-005646-xhx9pzhj 2993 2 treatment treatment NN cord-005646-xhx9pzhj 2993 3 is be VBZ cord-005646-xhx9pzhj 2993 4 effective effective JJ cord-005646-xhx9pzhj 2993 5 & & CC cord-005646-xhx9pzhj 2993 6 more more RBR cord-005646-xhx9pzhj 2993 7 preferable preferable JJ cord-005646-xhx9pzhj 2993 8 until until IN cord-005646-xhx9pzhj 2993 9 leucopenia leucopenia NNP cord-005646-xhx9pzhj 2993 10 resolves resolve VBZ cord-005646-xhx9pzhj 2993 11 . . . cord-005646-xhx9pzhj 2994 1 Operation operation NN cord-005646-xhx9pzhj 2994 2 is be VBZ cord-005646-xhx9pzhj 2994 3 necessary necessary JJ cord-005646-xhx9pzhj 2994 4 only only RB cord-005646-xhx9pzhj 2994 5 for for IN cord-005646-xhx9pzhj 2994 6 those.with those.with JJ cord-005646-xhx9pzhj 2994 7 perforation perforation NN cord-005646-xhx9pzhj 2994 8 . . . cord-005646-xhx9pzhj 2995 1 Near Near NNP cord-005646-xhx9pzhj 2995 2 Infrared Infrared NNP cord-005646-xhx9pzhj 2995 3 Spectroscopy Spectroscopy NNP cord-005646-xhx9pzhj 2995 4 as as IN cord-005646-xhx9pzhj 2995 5 a a DT cord-005646-xhx9pzhj 2995 6 tool tool NN cord-005646-xhx9pzhj 2995 7 for for IN cord-005646-xhx9pzhj 2995 8 evaluation evaluation NN cord-005646-xhx9pzhj 2995 9 of of IN cord-005646-xhx9pzhj 2995 10 intestinal intestinal JJ cord-005646-xhx9pzhj 2995 11 perfusionpresentation perfusionpresentation NN cord-005646-xhx9pzhj 2995 12 of of IN cord-005646-xhx9pzhj 2995 13 an an DT cord-005646-xhx9pzhj 2995 14 animal animal NN cord-005646-xhx9pzhj 2995 15 model model NN cord-005646-xhx9pzhj 2995 16 . . . cord-005646-xhx9pzhj 2996 1 C. C. NNP cord-005646-xhx9pzhj 2996 2 Scheibenpflug Scheibenpflug NNP cord-005646-xhx9pzhj 2996 3 , , , cord-005646-xhx9pzhj 2996 4 P. P. NNP cord-005646-xhx9pzhj 2996 5 Buxbaum Buxbaum NNP cord-005646-xhx9pzhj 2996 6 and and CC cord-005646-xhx9pzhj 2997 1 A.M. A.M. NNP cord-005646-xhx9pzhj 2997 2 Rokitansky Rokitansky NNP cord-005646-xhx9pzhj 2998 1 The the DT cord-005646-xhx9pzhj 2998 2 recent recent JJ cord-005646-xhx9pzhj 2998 3 development development NN cord-005646-xhx9pzhj 2998 4 of of IN cord-005646-xhx9pzhj 2998 5 and and CC cord-005646-xhx9pzhj 2998 6 investigations investigation NNS cord-005646-xhx9pzhj 2998 7 in in IN cord-005646-xhx9pzhj 2998 8 the the DT cord-005646-xhx9pzhj 2998 9 so so RB cord-005646-xhx9pzhj 2998 10 called call VBN cord-005646-xhx9pzhj 2998 11 Near Near NNP cord-005646-xhx9pzhj 2998 12 Infrared Infrared NNP cord-005646-xhx9pzhj 2998 13 Spectroscopy Spectroscopy NNP cord-005646-xhx9pzhj 2998 14 ( ( -LRB- cord-005646-xhx9pzhj 2998 15 NIRS NIRS NNP cord-005646-xhx9pzhj 2998 16 --transcutanous --transcutanous VBP cord-005646-xhx9pzhj 2998 17 emission emission NN cord-005646-xhx9pzhj 2998 18 and and CC cord-005646-xhx9pzhj 2998 19 simultaneous simultaneous JJ cord-005646-xhx9pzhj 2998 20 registration registration NN cord-005646-xhx9pzhj 2998 21 of of IN cord-005646-xhx9pzhj 2998 22 intensity intensity NN cord-005646-xhx9pzhj 2998 23 of of IN cord-005646-xhx9pzhj 2998 24 spectralcolours spectralcolour NNS cord-005646-xhx9pzhj 2998 25 depending depend VBG cord-005646-xhx9pzhj 2998 26 upon upon IN cord-005646-xhx9pzhj 2998 27 modulations modulation NNS cord-005646-xhx9pzhj 2998 28 of of IN cord-005646-xhx9pzhj 2998 29 tissue tissue NN cord-005646-xhx9pzhj 2998 30 perfusion perfusion NN cord-005646-xhx9pzhj 2998 31 ) ) -RRB- cord-005646-xhx9pzhj 2998 32 enable enable VB cord-005646-xhx9pzhj 2998 33 physicians physician NNS cord-005646-xhx9pzhj 2998 34 to to TO cord-005646-xhx9pzhj 2998 35 measure measure VB cord-005646-xhx9pzhj 2998 36 and and CC cord-005646-xhx9pzhj 2998 37 qualify qualify VB cord-005646-xhx9pzhj 2998 38 organ organ NN cord-005646-xhx9pzhj 2998 39 perfusion perfusion NN cord-005646-xhx9pzhj 2998 40 and and CC cord-005646-xhx9pzhj 2998 41 nowadays nowadays RB cord-005646-xhx9pzhj 2998 42 is be VBZ cord-005646-xhx9pzhj 2998 43 mainly mainly RB cord-005646-xhx9pzhj 2998 44 used use VBN cord-005646-xhx9pzhj 2998 45 to to TO cord-005646-xhx9pzhj 2998 46 control control VB cord-005646-xhx9pzhj 2998 47 cerebral cerebral JJ cord-005646-xhx9pzhj 2998 48 as as RB cord-005646-xhx9pzhj 2998 49 well well RB cord-005646-xhx9pzhj 2998 50 as as IN cord-005646-xhx9pzhj 2998 51 skeleton skeleton NN cord-005646-xhx9pzhj 2998 52 muscular muscular JJ cord-005646-xhx9pzhj 2998 53 blood blood NN cord-005646-xhx9pzhj 2998 54 flow flow NN cord-005646-xhx9pzhj 2998 55 in in IN cord-005646-xhx9pzhj 2998 56 trauma trauma NN cord-005646-xhx9pzhj 2998 57 patients patient NNS cord-005646-xhx9pzhj 2998 58 at at IN cord-005646-xhx9pzhj 2998 59 intensive intensive JJ cord-005646-xhx9pzhj 2998 60 care care NN cord-005646-xhx9pzhj 2998 61 units unit NNS cord-005646-xhx9pzhj 2998 62 ( ( -LRB- cord-005646-xhx9pzhj 2998 63 ICU ICU NNP cord-005646-xhx9pzhj 2998 64 ) ) -RRB- cord-005646-xhx9pzhj 2998 65 . . . cord-005646-xhx9pzhj 2999 1 Today today NN cord-005646-xhx9pzhj 2999 2 intestinal intestinal JJ cord-005646-xhx9pzhj 2999 3 perfusion perfusion NN cord-005646-xhx9pzhj 2999 4 , , , cord-005646-xhx9pzhj 2999 5 hypoperfusion hypoperfusion NN cord-005646-xhx9pzhj 2999 6 , , , cord-005646-xhx9pzhj 2999 7 cell cell NN cord-005646-xhx9pzhj 2999 8 damage damage NN cord-005646-xhx9pzhj 2999 9 caused cause VBN cord-005646-xhx9pzhj 2999 10 by by IN cord-005646-xhx9pzhj 2999 11 reperfusion reperfusion NN cord-005646-xhx9pzhj 2999 12 injury injury NN cord-005646-xhx9pzhj 2999 13 , , , cord-005646-xhx9pzhj 2999 14 bacterial bacterial JJ cord-005646-xhx9pzhj 2999 15 and and CC cord-005646-xhx9pzhj 2999 16 toxin toxin NN cord-005646-xhx9pzhj 2999 17 translocation translocation NN cord-005646-xhx9pzhj 2999 18 are be VBP cord-005646-xhx9pzhj 2999 19 serious serious JJ cord-005646-xhx9pzhj 2999 20 problems problem NNS cord-005646-xhx9pzhj 2999 21 in in IN cord-005646-xhx9pzhj 2999 22 critically critically RB cord-005646-xhx9pzhj 2999 23 ill ill JJ cord-005646-xhx9pzhj 2999 24 patients patient NNS cord-005646-xhx9pzhj 2999 25 at at IN cord-005646-xhx9pzhj 2999 26 an an DT cord-005646-xhx9pzhj 2999 27 ICU ICU NNP cord-005646-xhx9pzhj 2999 28 . . . cord-005646-xhx9pzhj 3000 1 Paediatric paediatric JJ cord-005646-xhx9pzhj 3000 2 intensive intensive JJ cord-005646-xhx9pzhj 3000 3 care care NN cord-005646-xhx9pzhj 3000 4 physicians physician NNS cord-005646-xhx9pzhj 3000 5 put put VBP cord-005646-xhx9pzhj 3000 6 major major JJ cord-005646-xhx9pzhj 3000 7 concern concern NN cord-005646-xhx9pzhj 3000 8 on on IN cord-005646-xhx9pzhj 3000 9 intestinal intestinal JJ cord-005646-xhx9pzhj 3000 10 perfusion perfusion NN cord-005646-xhx9pzhj 3000 11 , , , cord-005646-xhx9pzhj 3000 12 which which WDT cord-005646-xhx9pzhj 3000 13 for for IN cord-005646-xhx9pzhj 3000 14 . . . cord-005646-xhx9pzhj 3001 1 instance instance NN cord-005646-xhx9pzhj 3001 2 gains gain VBZ cord-005646-xhx9pzhj 3001 3 more more RBR cord-005646-xhx9pzhj 3001 4 and and CC cord-005646-xhx9pzhj 3001 5 more more JJR cord-005646-xhx9pzhj 3001 6 importance importance NN cord-005646-xhx9pzhj 3001 7 , , , cord-005646-xhx9pzhj 3001 8 especially especially RB cord-005646-xhx9pzhj 3001 9 in in IN cord-005646-xhx9pzhj 3001 10 the the DT cord-005646-xhx9pzhj 3001 11 neonatal neonatal JJ cord-005646-xhx9pzhj 3001 12 period period NN cord-005646-xhx9pzhj 3001 13 for for IN cord-005646-xhx9pzhj 3001 14 example example NN cord-005646-xhx9pzhj 3001 15 as as IN cord-005646-xhx9pzhj 3001 16 an an DT cord-005646-xhx9pzhj 3001 17 etiologic etiologic JJ cord-005646-xhx9pzhj 3001 18 factor factor NN cord-005646-xhx9pzhj 3001 19 for for IN cord-005646-xhx9pzhj 3001 20 necrotizing necrotize VBG cord-005646-xhx9pzhj 3001 21 enterocolitis enterocolitis NN cord-005646-xhx9pzhj 3001 22 . . . cord-005646-xhx9pzhj 3002 1 We -PRON- PRP cord-005646-xhx9pzhj 3002 2 established establish VBD cord-005646-xhx9pzhj 3002 3 an an DT cord-005646-xhx9pzhj 3002 4 animal animal NN cord-005646-xhx9pzhj 3002 5 model model NN cord-005646-xhx9pzhj 3002 6 , , , cord-005646-xhx9pzhj 3002 7 in in IN cord-005646-xhx9pzhj 3002 8 which which WDT cord-005646-xhx9pzhj 3002 9 we -PRON- PRP cord-005646-xhx9pzhj 3002 10 measured measure VBD cord-005646-xhx9pzhj 3002 11 intestinal intestinal JJ cord-005646-xhx9pzhj 3002 12 perfusion perfusion NN cord-005646-xhx9pzhj 3002 13 by by IN cord-005646-xhx9pzhj 3002 14 NIRS NIRS NNP cord-005646-xhx9pzhj 3002 15 under under IN cord-005646-xhx9pzhj 3002 16 various various JJ cord-005646-xhx9pzhj 3002 17 invasive invasive JJ cord-005646-xhx9pzhj 3002 18 and and CC cord-005646-xhx9pzhj 3002 19 noninvasive noninvasive JJ cord-005646-xhx9pzhj 3002 20 conditions condition NNS cord-005646-xhx9pzhj 3002 21 . . . cord-005646-xhx9pzhj 3003 1 Methods method NNS cord-005646-xhx9pzhj 3003 2 and and CC cord-005646-xhx9pzhj 3003 3 results result NNS cord-005646-xhx9pzhj 3003 4 will will MD cord-005646-xhx9pzhj 3003 5 be be VB cord-005646-xhx9pzhj 3003 6 referred refer VBN cord-005646-xhx9pzhj 3003 7 . . . cord-005646-xhx9pzhj 3004 1 For for IN cord-005646-xhx9pzhj 3004 2 preliminary preliminary JJ cord-005646-xhx9pzhj 3004 3 conclusion conclusion NN cord-005646-xhx9pzhj 3004 4 we -PRON- PRP cord-005646-xhx9pzhj 3004 5 propose propose VBP cord-005646-xhx9pzhj 3004 6 Near near IN cord-005646-xhx9pzhj 3004 7 Infrared Infrared NNP cord-005646-xhx9pzhj 3004 8 Spectroscopy Spectroscopy NNP cord-005646-xhx9pzhj 3004 9 ( ( -LRB- cord-005646-xhx9pzhj 3004 10 NIRS NIRS NNP cord-005646-xhx9pzhj 3004 11 ) ) -RRB- cord-005646-xhx9pzhj 3004 12 also also RB cord-005646-xhx9pzhj 3004 13 as as IN cord-005646-xhx9pzhj 3004 14 a a DT cord-005646-xhx9pzhj 3004 15 potent potent JJ cord-005646-xhx9pzhj 3004 16 diagnostic diagnostic JJ cord-005646-xhx9pzhj 3004 17 tool tool NN cord-005646-xhx9pzhj 3004 18 to to TO cord-005646-xhx9pzhj 3004 19 determine determine VB cord-005646-xhx9pzhj 3004 20 early early JJ cord-005646-xhx9pzhj 3004 21 intestinal intestinal JJ cord-005646-xhx9pzhj 3004 22 malperfusion malperfusion NN cord-005646-xhx9pzhj 3004 23 in in IN cord-005646-xhx9pzhj 3004 24 order order NN cord-005646-xhx9pzhj 3004 25 to to TO cord-005646-xhx9pzhj 3004 26 prevent prevent VB cord-005646-xhx9pzhj 3004 27 lethal lethal JJ cord-005646-xhx9pzhj 3004 28 outcome outcome NN cord-005646-xhx9pzhj 3004 29 . . . cord-005646-xhx9pzhj 3005 1 Fm'ther fm'ther JJ cord-005646-xhx9pzhj 3005 2 investigations investigation NNS cord-005646-xhx9pzhj 3005 3 in in IN cord-005646-xhx9pzhj 3005 4 animals animal NNS cord-005646-xhx9pzhj 3005 5 as as RB cord-005646-xhx9pzhj 3005 6 well well RB cord-005646-xhx9pzhj 3005 7 in in IN cord-005646-xhx9pzhj 3005 8 paediatric paediatric JJ cord-005646-xhx9pzhj 3005 9 iritensive iritensive NN cord-005646-xhx9pzhj 3005 10 care care NN cord-005646-xhx9pzhj 3005 11 patients patient NNS cord-005646-xhx9pzhj 3005 12 should should MD cord-005646-xhx9pzhj 3005 13 be be VB cord-005646-xhx9pzhj 3005 14 done do VBN cord-005646-xhx9pzhj 3005 15 to to TO cord-005646-xhx9pzhj 3005 16 estimate estimate VB cord-005646-xhx9pzhj 3005 17 our -PRON- PRP$ cord-005646-xhx9pzhj 3005 18 efforts effort NNS cord-005646-xhx9pzhj 3005 19 . . . cord-005646-xhx9pzhj 3006 1 Introduction introduction NN cord-005646-xhx9pzhj 3006 2 : : : cord-005646-xhx9pzhj 3007 1 Following follow VBG cord-005646-xhx9pzhj 3007 2 the the DT cord-005646-xhx9pzhj 3007 3 acute acute JJ cord-005646-xhx9pzhj 3007 4 phase phase NN cord-005646-xhx9pzhj 3007 5 of of IN cord-005646-xhx9pzhj 3007 6 necrotising necrotise VBG cord-005646-xhx9pzhj 3007 7 enterocolitis enterocolitis NN cord-005646-xhx9pzhj 3007 8 ( ( -LRB- cord-005646-xhx9pzhj 3007 9 NEC NEC NNP cord-005646-xhx9pzhj 3007 10 ) ) -RRB- cord-005646-xhx9pzhj 3007 11 starvation starvation NN cord-005646-xhx9pzhj 3007 12 of of IN cord-005646-xhx9pzhj 3007 13 the the DT cord-005646-xhx9pzhj 3007 14 gut gut NN cord-005646-xhx9pzhj 3007 15 for for IN cord-005646-xhx9pzhj 3007 16 a a DT cord-005646-xhx9pzhj 3007 17 period period NN cord-005646-xhx9pzhj 3007 18 up up IN cord-005646-xhx9pzhj 3007 19 to to TO cord-005646-xhx9pzhj 3007 20 3 3 CD cord-005646-xhx9pzhj 3007 21 weeks week NNS cord-005646-xhx9pzhj 3007 22 is be VBZ cord-005646-xhx9pzhj 3007 23 a a DT cord-005646-xhx9pzhj 3007 24 generally generally RB cord-005646-xhx9pzhj 3007 25 accepted accept VBN cord-005646-xhx9pzhj 3007 26 treatment treatment NN cord-005646-xhx9pzhj 3007 27 modality modality NN cord-005646-xhx9pzhj 3007 28 in in IN cord-005646-xhx9pzhj 3007 29 many many JJ cord-005646-xhx9pzhj 3007 30 centres centre NNS cord-005646-xhx9pzhj 3007 31 . . . cord-005646-xhx9pzhj 3008 1 Objective objective JJ cord-005646-xhx9pzhj 3008 2 criteria criterion NNS cord-005646-xhx9pzhj 3008 3 to to TO cord-005646-xhx9pzhj 3008 4 refeed refeed VB cord-005646-xhx9pzhj 3008 5 these these DT cord-005646-xhx9pzhj 3008 6 patients patient NNS cord-005646-xhx9pzhj 3008 7 are be VBP cord-005646-xhx9pzhj 3008 8 hardly hardly RB cord-005646-xhx9pzhj 3008 9 available available JJ cord-005646-xhx9pzhj 3008 10 . . . cord-005646-xhx9pzhj 3009 1 Recently recently RB cord-005646-xhx9pzhj 3009 2 the the DT cord-005646-xhx9pzhj 3009 3 double double JJ cord-005646-xhx9pzhj 3009 4 sugar sugar NN cord-005646-xhx9pzhj 3009 5 test test NN cord-005646-xhx9pzhj 3009 6 has have VBZ cord-005646-xhx9pzhj 3009 7 become become VBN cord-005646-xhx9pzhj 3009 8 available available JJ cord-005646-xhx9pzhj 3009 9 as as IN cord-005646-xhx9pzhj 3009 10 a a DT cord-005646-xhx9pzhj 3009 11 parameter parameter NN cord-005646-xhx9pzhj 3009 12 for for IN cord-005646-xhx9pzhj 3009 13 ( ( -LRB- cord-005646-xhx9pzhj 3009 14 ab)normal ab)normal NNP cord-005646-xhx9pzhj 3009 15 gut gut NN cord-005646-xhx9pzhj 3009 16 permeability permeability NN cord-005646-xhx9pzhj 3009 17 ~'2 ~'2 NFP cord-005646-xhx9pzhj 3009 18 . . . cord-005646-xhx9pzhj 3010 1 Aim Aim NNP cord-005646-xhx9pzhj 3010 2 of of IN cord-005646-xhx9pzhj 3010 3 the the DT cord-005646-xhx9pzhj 3010 4 study study NN cord-005646-xhx9pzhj 3010 5 : : : cord-005646-xhx9pzhj 3010 6 To to TO cord-005646-xhx9pzhj 3010 7 evaluate evaluate VB cord-005646-xhx9pzhj 3010 8 the the DT cord-005646-xhx9pzhj 3010 9 changes change NNS cord-005646-xhx9pzhj 3010 10 in in IN cord-005646-xhx9pzhj 3010 11 permeability permeability NN cord-005646-xhx9pzhj 3010 12 of of IN cord-005646-xhx9pzhj 3010 13 the the DT cord-005646-xhx9pzhj 3010 14 small small JJ cord-005646-xhx9pzhj 3010 15 bowel bowel NN cord-005646-xhx9pzhj 3010 16 in in IN cord-005646-xhx9pzhj 3010 17 patients patient NNS cord-005646-xhx9pzhj 3010 18 with with IN cord-005646-xhx9pzhj 3010 19 NEC NEC NNP cord-005646-xhx9pzhj 3010 20 and and CC cord-005646-xhx9pzhj 3010 21 controls control NNS cord-005646-xhx9pzhj 3010 22 before before IN cord-005646-xhx9pzhj 3010 23 introduction introduction NN cord-005646-xhx9pzhj 3010 24 of of IN cord-005646-xhx9pzhj 3010 25 enteral enteral JJ cord-005646-xhx9pzhj 3010 26 feeding feeding NN cord-005646-xhx9pzhj 3010 27 . . . cord-005646-xhx9pzhj 3011 1 Methods method NNS cord-005646-xhx9pzhj 3011 2 : : : cord-005646-xhx9pzhj 3012 1 A a DT cord-005646-xhx9pzhj 3012 2 lactulose lactulose NN cord-005646-xhx9pzhj 3012 3 ! ! . cord-005646-xhx9pzhj 3013 1 rbarrmose rbarrmose NNP cord-005646-xhx9pzhj 3014 1 ( ( -LRB- cord-005646-xhx9pzhj 3014 2 I i NN cord-005646-xhx9pzhj 3014 3 / / SYM cord-005646-xhx9pzhj 3014 4 r r NN cord-005646-xhx9pzhj 3014 5 ) ) -RRB- cord-005646-xhx9pzhj 3014 6 test test NN cord-005646-xhx9pzhj 3014 7 was be VBD cord-005646-xhx9pzhj 3014 8 performed perform VBN cord-005646-xhx9pzhj 3014 9 in in IN cord-005646-xhx9pzhj 3014 10 two two CD cord-005646-xhx9pzhj 3014 11 groups group NNS cord-005646-xhx9pzhj 3014 12 . . . cord-005646-xhx9pzhj 3015 1 Group group NN cord-005646-xhx9pzhj 3015 2 1 1 CD cord-005646-xhx9pzhj 3015 3 was be VBD cord-005646-xhx9pzhj 3015 4 studied study VBN cord-005646-xhx9pzhj 3015 5 2 2 CD cord-005646-xhx9pzhj 3015 6 - - SYM cord-005646-xhx9pzhj 3015 7 3 3 CD cord-005646-xhx9pzhj 3015 8 times time NNS cord-005646-xhx9pzhj 3015 9 within within IN cord-005646-xhx9pzhj 3015 10 a a DT cord-005646-xhx9pzhj 3015 11 5-week 5-week CD cord-005646-xhx9pzhj 3015 12 period period NN cord-005646-xhx9pzhj 3015 13 of of IN cord-005646-xhx9pzhj 3015 14 starvation starvation NN cord-005646-xhx9pzhj 3015 15 ( ( -LRB- cord-005646-xhx9pzhj 3015 16 n=5 n=5 JJ cord-005646-xhx9pzhj 3015 17 , , , cord-005646-xhx9pzhj 3015 18 mean mean NNP cord-005646-xhx9pzhj 3015 19 gest gest NNP cord-005646-xhx9pzhj 3015 20 . . . cord-005646-xhx9pzhj 3016 1 age age NN cord-005646-xhx9pzhj 3016 2 35 35 CD cord-005646-xhx9pzhj 3016 3 , , , cord-005646-xhx9pzhj 3016 4 range range VBP cord-005646-xhx9pzhj 3016 5 31 31 CD cord-005646-xhx9pzhj 3016 6 - - SYM cord-005646-xhx9pzhj 3016 7 40 40 CD cord-005646-xhx9pzhj 3016 8 weeks week NNS cord-005646-xhx9pzhj 3016 9 ) ) -RRB- cord-005646-xhx9pzhj 3016 10 . . . cord-005646-xhx9pzhj 3017 1 In in IN cord-005646-xhx9pzhj 3017 2 group group NN cord-005646-xhx9pzhj 3017 3 2 2 CD cord-005646-xhx9pzhj 3017 4 seven seven CD cord-005646-xhx9pzhj 3017 5 different different JJ cord-005646-xhx9pzhj 3017 6 control control NN cord-005646-xhx9pzhj 3017 7 patients patient NNS cord-005646-xhx9pzhj 3017 8 were be VBD cord-005646-xhx9pzhj 3017 9 studied study VBN cord-005646-xhx9pzhj 3017 10 ( ( -LRB- cord-005646-xhx9pzhj 3017 11 mean mean VB cord-005646-xhx9pzhj 3017 12 gest.age gest.age NNP cord-005646-xhx9pzhj 3017 13 33 33 CD cord-005646-xhx9pzhj 3017 14 , , , cord-005646-xhx9pzhj 3017 15 range range VBP cord-005646-xhx9pzhj 3017 16 28 28 CD cord-005646-xhx9pzhj 3017 17 - - SYM cord-005646-xhx9pzhj 3017 18 38 38 CD cord-005646-xhx9pzhj 3017 19 weeks week NNS cord-005646-xhx9pzhj 3017 20 ) ) -RRB- cord-005646-xhx9pzhj 3017 21 . . . cord-005646-xhx9pzhj 3018 1 The the DT cord-005646-xhx9pzhj 3018 2 test test NN cord-005646-xhx9pzhj 3018 3 was be VBD cord-005646-xhx9pzhj 3018 4 performed perform VBN cord-005646-xhx9pzhj 3018 5 by by IN cord-005646-xhx9pzhj 3018 6 giving give VBG cord-005646-xhx9pzhj 3018 7 a a DT cord-005646-xhx9pzhj 3018 8 patient patient NN cord-005646-xhx9pzhj 3018 9 after after IN cord-005646-xhx9pzhj 3018 10 at at RB cord-005646-xhx9pzhj 3018 11 least least JJS cord-005646-xhx9pzhj 3018 12 a a DT cord-005646-xhx9pzhj 3018 13 4 4 CD cord-005646-xhx9pzhj 3018 14 hour hour NN cord-005646-xhx9pzhj 3018 15 fast fast JJ cord-005646-xhx9pzhj 3018 16 1 1 CD cord-005646-xhx9pzhj 3018 17 ml ml NNS cord-005646-xhx9pzhj 3018 18 / / SYM cord-005646-xhx9pzhj 3018 19 kg kg NNP cord-005646-xhx9pzhj 3018 20 bodyweight bodyweight NN cord-005646-xhx9pzhj 3018 21 l l NNP cord-005646-xhx9pzhj 3018 22 / / SYM cord-005646-xhx9pzhj 3018 23 r r NN cord-005646-xhx9pzhj 3018 24 solution solution NN cord-005646-xhx9pzhj 3018 25 and and CC cord-005646-xhx9pzhj 3018 26 determination determination NN cord-005646-xhx9pzhj 3018 27 of of IN cord-005646-xhx9pzhj 3018 28 the the DT cord-005646-xhx9pzhj 3018 29 1 1 CD cord-005646-xhx9pzhj 3018 30 / / SYM cord-005646-xhx9pzhj 3018 31 r r NN cord-005646-xhx9pzhj 3018 32 ratio ratio NN cord-005646-xhx9pzhj 3018 33 in in IN cord-005646-xhx9pzhj 3018 34 a a DT cord-005646-xhx9pzhj 3018 35 4-hour 4-hour CD cord-005646-xhx9pzhj 3018 36 urine urine NN cord-005646-xhx9pzhj 3018 37 sample sample NN cord-005646-xhx9pzhj 3018 38 by by IN cord-005646-xhx9pzhj 3018 39 chromatography chromatography NN cord-005646-xhx9pzhj 3018 40 . . . cord-005646-xhx9pzhj 3019 1 Results result NNS cord-005646-xhx9pzhj 3019 2 : : : cord-005646-xhx9pzhj 3020 1 Objective objective NN cord-005646-xhx9pzhj 3020 2 : : : cord-005646-xhx9pzhj 3021 1 To to TO cord-005646-xhx9pzhj 3021 2 evaluate evaluate VB cord-005646-xhx9pzhj 3021 3 the the DT cord-005646-xhx9pzhj 3021 4 prognostic prognostic JJ cord-005646-xhx9pzhj 3021 5 factors factor NNS cord-005646-xhx9pzhj 3021 6 in in IN cord-005646-xhx9pzhj 3021 7 the the DT cord-005646-xhx9pzhj 3021 8 response response NN cord-005646-xhx9pzhj 3021 9 to to IN cord-005646-xhx9pzhj 3021 10 nitric nitric NN cord-005646-xhx9pzhj 3021 11 oxide oxide NN cord-005646-xhx9pzhj 3021 12 ( ( -LRB- cord-005646-xhx9pzhj 3021 13 NO no UH cord-005646-xhx9pzhj 3021 14 ) ) -RRB- cord-005646-xhx9pzhj 3021 15 in in IN cord-005646-xhx9pzhj 3021 16 children child NNS cord-005646-xhx9pzhj 3021 17 with with IN cord-005646-xhx9pzhj 3021 18 Acute Acute NNP cord-005646-xhx9pzhj 3021 19 Respirator/ Respirator/ NNP cord-005646-xhx9pzhj 3021 20 Distress Distress NNP cord-005646-xhx9pzhj 3021 21 Syndrome Syndrome NNP cord-005646-xhx9pzhj 3021 22 ( ( -LRB- cord-005646-xhx9pzhj 3021 23 ARDS ARDS NNP cord-005646-xhx9pzhj 3021 24 ) ) -RRB- cord-005646-xhx9pzhj 3021 25 and/or and/or CC cord-005646-xhx9pzhj 3021 26 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3021 27 hypertension hypertension NN cord-005646-xhx9pzhj 3021 28 ( ( -LRB- cord-005646-xhx9pzhj 3021 29 PHT PHT NNP cord-005646-xhx9pzhj 3021 30 ) ) -RRB- cord-005646-xhx9pzhj 3021 31 . . . cord-005646-xhx9pzhj 3022 1 Patients patient NNS cord-005646-xhx9pzhj 3022 2 and and CC cord-005646-xhx9pzhj 3022 3 methods method NNS cord-005646-xhx9pzhj 3022 4 : : : cord-005646-xhx9pzhj 3022 5 23 23 CD cord-005646-xhx9pzhj 3022 6 critically critically RB cord-005646-xhx9pzhj 3022 7 ill ill JJ cord-005646-xhx9pzhj 3022 8 children child NNS cord-005646-xhx9pzhj 3022 9 received receive VBD cord-005646-xhx9pzhj 3022 10 NO no RB cord-005646-xhx9pzhj 3022 11 inhaled inhale VBN cord-005646-xhx9pzhj 3022 12 for for IN cord-005646-xhx9pzhj 3022 13 AnDS AnDS NNP cord-005646-xhx9pzhj 3022 14 and/or and/or CC cord-005646-xhx9pzhj 3022 15 PHT PHT NNP cord-005646-xhx9pzhj 3022 16 treatment treatment NN cord-005646-xhx9pzhj 3022 17 . . . cord-005646-xhx9pzhj 3023 1 14 14 CD cord-005646-xhx9pzhj 3023 2 patient patient NN cord-005646-xhx9pzhj 3023 3 before before IN cord-005646-xhx9pzhj 3023 4 and and CC cord-005646-xhx9pzhj 3023 5 after after IN cord-005646-xhx9pzhj 3023 6 cardiac cardiac JJ cord-005646-xhx9pzhj 3023 7 surgery surgery NN cord-005646-xhx9pzhj 3023 8 ( ( -LRB- cord-005646-xhx9pzhj 3023 9 2 2 CD cord-005646-xhx9pzhj 3023 10 cardiac cardiac JJ cord-005646-xhx9pzhj 3023 11 transplants transplant NNS cord-005646-xhx9pzhj 3023 12 ) ) -RRB- cord-005646-xhx9pzhj 3023 13 , , , cord-005646-xhx9pzhj 3023 14 5 5 CD cord-005646-xhx9pzhj 3023 15 with with IN cord-005646-xhx9pzhj 3023 16 bronchopneu bronchopneu NN cord-005646-xhx9pzhj 3023 17 ~ ~ NFP cord-005646-xhx9pzhj 3023 18 onia onia NNP cord-005646-xhx9pzhj 3023 19 , , , cord-005646-xhx9pzhj 3023 20 2 2 CD cord-005646-xhx9pzhj 3023 21 multiple multiple JJ cord-005646-xhx9pzhj 3023 22 trauma trauma NN cord-005646-xhx9pzhj 3023 23 , , , cord-005646-xhx9pzhj 3023 24 1 1 CD cord-005646-xhx9pzhj 3023 25 sepsis sepsis NN cord-005646-xhx9pzhj 3023 26 and and CC cord-005646-xhx9pzhj 3023 27 1 1 CD cord-005646-xhx9pzhj 3023 28 cardiorespiratory cardiorespiratory JJ cord-005646-xhx9pzhj 3023 29 arrest arrest NN cord-005646-xhx9pzhj 3023 30 . . . cord-005646-xhx9pzhj 3024 1 15 15 CD cord-005646-xhx9pzhj 3024 2 patients patient NNS cord-005646-xhx9pzhj 3024 3 showed show VBD cord-005646-xhx9pzhj 3024 4 /J /j NN cord-005646-xhx9pzhj 3024 5 ~ ~ NFP cord-005646-xhx9pzhj 3024 6 DS DS NNP cord-005646-xhx9pzhj 3024 7 and and CC cord-005646-xhx9pzhj 3024 8 8 8 CD cord-005646-xhx9pzhj 3024 9 PHT PHT NNP cord-005646-xhx9pzhj 3024 10 , , , cord-005646-xhx9pzhj 3024 11 in in IN cord-005646-xhx9pzhj 3024 12 4 4 CD cord-005646-xhx9pzhj 3024 13 with with IN cord-005646-xhx9pzhj 3024 14 associated associated JJ cord-005646-xhx9pzhj 3024 15 ARDS ARDS NNP cord-005646-xhx9pzhj 3024 16 . . . cord-005646-xhx9pzhj 3025 1 We -PRON- PRP cord-005646-xhx9pzhj 3025 2 analyzed analyze VBD cord-005646-xhx9pzhj 3025 3 age age NN cord-005646-xhx9pzhj 3025 4 , , , cord-005646-xhx9pzhj 3025 5 sex sex NN cord-005646-xhx9pzhj 3025 6 , , , cord-005646-xhx9pzhj 3025 7 diagnosis diagnosis NN cord-005646-xhx9pzhj 3025 8 , , , cord-005646-xhx9pzhj 3025 9 PaO2 PaO2 NNS cord-005646-xhx9pzhj 3025 10 , , , cord-005646-xhx9pzhj 3025 11 Pa02 Pa02 NNP cord-005646-xhx9pzhj 3025 12 / / SYM cord-005646-xhx9pzhj 3025 13 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3025 14 , , , cord-005646-xhx9pzhj 3025 15 Oxygenation Oxygenation NNP cord-005646-xhx9pzhj 3025 16 Index Index NNP cord-005646-xhx9pzhj 3025 17 , , , cord-005646-xhx9pzhj 3025 18 PHT PHT NNP cord-005646-xhx9pzhj 3025 19 , , , cord-005646-xhx9pzhj 3025 20 shock shock NN cord-005646-xhx9pzhj 3025 21 , , , cord-005646-xhx9pzhj 3025 22 and and CC cord-005646-xhx9pzhj 3025 23 sepsis sepsis NN cord-005646-xhx9pzhj 3025 24 as as IN cord-005646-xhx9pzhj 3025 25 prognostic prognostic JJ cord-005646-xhx9pzhj 3025 26 factors factor NNS cord-005646-xhx9pzhj 3025 27 and and CC cord-005646-xhx9pzhj 3025 28 response response NN cord-005646-xhx9pzhj 3025 29 factors factor NNS cord-005646-xhx9pzhj 3025 30 to to IN cord-005646-xhx9pzhj 3025 31 N0 N0 NNP cord-005646-xhx9pzhj 3025 32 . . . cord-005646-xhx9pzhj 3026 1 Results result NNS cord-005646-xhx9pzhj 3026 2 : : : cord-005646-xhx9pzhj 3027 1 After after IN cord-005646-xhx9pzhj 3027 2 NO no DT cord-005646-xhx9pzhj 3027 3 administration administration NN cord-005646-xhx9pzhj 3027 4 oxygenation oxygenation NN cord-005646-xhx9pzhj 3027 5 did do VBD cord-005646-xhx9pzhj 3027 6 not not RB cord-005646-xhx9pzhj 3027 7 improve improve VB cord-005646-xhx9pzhj 3027 8 in in IN cord-005646-xhx9pzhj 3027 9 2 2 CD cord-005646-xhx9pzhj 3027 10 patients patient NNS cord-005646-xhx9pzhj 3027 11 ( ( -LRB- cord-005646-xhx9pzhj 3027 12 8.6 8.6 CD cord-005646-xhx9pzhj 3027 13 % % NN cord-005646-xhx9pzhj 3027 14 ) ) -RRB- cord-005646-xhx9pzhj 3027 15 and and CC cord-005646-xhx9pzhj 3027 16 PHT PHT NNP cord-005646-xhx9pzhj 3027 17 did do VBD cord-005646-xhx9pzhj 3027 18 not not RB cord-005646-xhx9pzhj 3027 19 diminishe diminishe VB cord-005646-xhx9pzhj 3027 20 in in IN cord-005646-xhx9pzhj 3027 21 one one CD cord-005646-xhx9pzhj 3027 22 children child NNS cord-005646-xhx9pzhj 3027 23 ( ( -LRB- cord-005646-xhx9pzhj 3027 24 12 12 CD cord-005646-xhx9pzhj 3027 25 % % NN cord-005646-xhx9pzhj 3027 26 ) ) -RRB- cord-005646-xhx9pzhj 3027 27 . . . cord-005646-xhx9pzhj 3028 1 12 12 CD cord-005646-xhx9pzhj 3028 2 patients patient NNS cord-005646-xhx9pzhj 3028 3 survived survive VBD cord-005646-xhx9pzhj 3028 4 ( ( -LRB- cord-005646-xhx9pzhj 3028 5 52 52 CD cord-005646-xhx9pzhj 3028 6 % % NN cord-005646-xhx9pzhj 3028 7 ) ) -RRB- cord-005646-xhx9pzhj 3028 8 , , , cord-005646-xhx9pzhj 3028 9 8/15 8/15 CD cord-005646-xhx9pzhj 3028 10 ( ( -LRB- cord-005646-xhx9pzhj 3028 11 53.3 53.3 CD cord-005646-xhx9pzhj 3028 12 % % NN cord-005646-xhx9pzhj 3028 13 with with IN cord-005646-xhx9pzhj 3028 14 /d%DS /d%DS NNP cord-005646-xhx9pzhj 3028 15 ) ) -RRB- cord-005646-xhx9pzhj 3028 16 and and CC cord-005646-xhx9pzhj 3028 17 4 4 CD cord-005646-xhx9pzhj 3028 18 /8 /8 . cord-005646-xhx9pzhj 3029 1 ( ( -LRB- cord-005646-xhx9pzhj 3029 2 50 50 CD cord-005646-xhx9pzhj 3029 3 % % NN cord-005646-xhx9pzhj 3029 4 ) ) -RRB- cord-005646-xhx9pzhj 3029 5 with with IN cord-005646-xhx9pzhj 3029 6 PHT PHT NNP cord-005646-xhx9pzhj 3029 7 . . . cord-005646-xhx9pzhj 3030 1 The the DT cord-005646-xhx9pzhj 3030 2 four four CD cord-005646-xhx9pzhj 3030 3 patients patient NNS cord-005646-xhx9pzhj 3030 4 with with IN cord-005646-xhx9pzhj 3030 5 isolated isolate VBN cord-005646-xhx9pzhj 3030 6 PHT PHT NNP cord-005646-xhx9pzhj 3030 7 survived survive VBD cord-005646-xhx9pzhj 3030 8 , , , cord-005646-xhx9pzhj 3030 9 and and CC cord-005646-xhx9pzhj 3030 10 the the DT cord-005646-xhx9pzhj 3030 11 4 4 CD cord-005646-xhx9pzhj 3030 12 patients patient NNS cord-005646-xhx9pzhj 3030 13 with with IN cord-005646-xhx9pzhj 3030 14 PHT PHT NNP cord-005646-xhx9pzhj 3030 15 and and CC cord-005646-xhx9pzhj 3030 16 ARDS ARDS NNP cord-005646-xhx9pzhj 3030 17 dead dead JJ cord-005646-xhx9pzhj 3030 18 . . . cord-005646-xhx9pzhj 3031 1 Patients patient NNS cord-005646-xhx9pzhj 3031 2 after after IN cord-005646-xhx9pzhj 3031 3 cardiac cardiac JJ cord-005646-xhx9pzhj 3031 4 surgery surgery NN cord-005646-xhx9pzhj 3031 5 presented present VBD cord-005646-xhx9pzhj 3031 6 less less JJR cord-005646-xhx9pzhj 3031 7 mortality mortality NN cord-005646-xhx9pzhj 3031 8 ( ( -LRB- cord-005646-xhx9pzhj 3031 9 35.7 35.7 CD cord-005646-xhx9pzhj 3031 10 % % NN cord-005646-xhx9pzhj 3031 11 ) ) -RRB- cord-005646-xhx9pzhj 3031 12 than than IN cord-005646-xhx9pzhj 3031 13 the the DT cord-005646-xhx9pzhj 3031 14 rest rest NN cord-005646-xhx9pzhj 3031 15 of of IN cord-005646-xhx9pzhj 3031 16 patients patient NNS cord-005646-xhx9pzhj 3031 17 ( ( -LRB- cord-005646-xhx9pzhj 3031 18 66.6 66.6 CD cord-005646-xhx9pzhj 3031 19 % % NN cord-005646-xhx9pzhj 3031 20 ) ) -RRB- cord-005646-xhx9pzhj 3031 21 . . . cord-005646-xhx9pzhj 3032 1 Patients patient NNS cord-005646-xhx9pzhj 3032 2 with with IN cord-005646-xhx9pzhj 3032 3 shock shock NN cord-005646-xhx9pzhj 3032 4 presented present VBD cord-005646-xhx9pzhj 3032 5 higher high JJR cord-005646-xhx9pzhj 3032 6 mortality mortality NN cord-005646-xhx9pzhj 3032 7 ( ( -LRB- cord-005646-xhx9pzhj 3032 8 64.2 64.2 CD cord-005646-xhx9pzhj 3032 9 % % NN cord-005646-xhx9pzhj 3032 10 ) ) -RRB- cord-005646-xhx9pzhj 3032 11 than than IN cord-005646-xhx9pzhj 3032 12 the the DT cord-005646-xhx9pzhj 3032 13 rest rest NN cord-005646-xhx9pzhj 3032 14 of of IN cord-005646-xhx9pzhj 3032 15 patients patient NNS cord-005646-xhx9pzhj 3032 16 ( ( -LRB- cord-005646-xhx9pzhj 3032 17 22.2 22.2 CD cord-005646-xhx9pzhj 3032 18 % % NN cord-005646-xhx9pzhj 3032 19 ) ) -RRB- cord-005646-xhx9pzhj 3032 20 . . . cord-005646-xhx9pzhj 3033 1 There there EX cord-005646-xhx9pzhj 3033 2 are be VBP cord-005646-xhx9pzhj 3033 3 no no DT cord-005646-xhx9pzhj 3033 4 differences difference NNS cord-005646-xhx9pzhj 3033 5 in in IN cord-005646-xhx9pzhj 3033 6 response response NN cord-005646-xhx9pzhj 3033 7 to to IN cord-005646-xhx9pzhj 3033 8 NO no RB cord-005646-xhx9pzhj 3033 9 in in IN cord-005646-xhx9pzhj 3033 10 respect respect NN cord-005646-xhx9pzhj 3033 11 of of IN cord-005646-xhx9pzhj 3033 12 sex sex NN cord-005646-xhx9pzhj 3033 13 , , , cord-005646-xhx9pzhj 3033 14 age age NN cord-005646-xhx9pzhj 3033 15 , , , cord-005646-xhx9pzhj 3033 16 diagnosis diagnosis NN cord-005646-xhx9pzhj 3033 17 , , , cord-005646-xhx9pzhj 3033 18 shock shock NN cord-005646-xhx9pzhj 3033 19 , , , cord-005646-xhx9pzhj 3033 20 and and CC cord-005646-xhx9pzhj 3033 21 sepsis sepsis NN cord-005646-xhx9pzhj 3033 22 . . . cord-005646-xhx9pzhj 3034 1 Survivors survivor NNS cord-005646-xhx9pzhj 3034 2 showed show VBD cord-005646-xhx9pzhj 3034 3 higher high JJR cord-005646-xhx9pzhj 3034 4 increase increase NN cord-005646-xhx9pzhj 3034 5 of of IN cord-005646-xhx9pzhj 3034 6 PaO2/ PaO2/ NNP cord-005646-xhx9pzhj 3035 1 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3036 1 64.3 64.3 CD cord-005646-xhx9pzhj 3036 2 ± ± CD cord-005646-xhx9pzhj 3036 3 58.4 58.4 CD cord-005646-xhx9pzhj 3036 4 to to IN cord-005646-xhx9pzhj 3036 5 NO no RB cord-005646-xhx9pzhj 3036 6 than than IN cord-005646-xhx9pzhj 3036 7 non non NNS cord-005646-xhx9pzhj 3036 8 - - NNS cord-005646-xhx9pzhj 3036 9 survivors survivor NNS cord-005646-xhx9pzhj 3036 10 48.4 48.4 CD cord-005646-xhx9pzhj 3036 11 ± ± CD cord-005646-xhx9pzhj 3036 12 51.1 51.1 CD cord-005646-xhx9pzhj 3036 13 ( ( -LRB- cord-005646-xhx9pzhj 3036 14 N.S N.S NNP cord-005646-xhx9pzhj 3036 15 ) ) -RRB- cord-005646-xhx9pzhj 3036 16 . . . cord-005646-xhx9pzhj 3037 1 Patients patient NNS cord-005646-xhx9pzhj 3037 2 with with IN cord-005646-xhx9pzhj 3037 3 PHT PHT NNP cord-005646-xhx9pzhj 3037 4 showed show VBD cord-005646-xhx9pzhj 3037 5 higher high JJR cord-005646-xhx9pzhj 3037 6 increase increase NN cord-005646-xhx9pzhj 3037 7 in in IN cord-005646-xhx9pzhj 3037 8 Pa02/ pa02/ NN cord-005646-xhx9pzhj 3038 1 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3039 1 to to IN cord-005646-xhx9pzhj 3039 2 NO no DT cord-005646-xhx9pzhj 3039 3 administration administration NN cord-005646-xhx9pzhj 3039 4 ( ( -LRB- cord-005646-xhx9pzhj 3039 5 88 88 CD cord-005646-xhx9pzhj 3039 6 ± ± CD cord-005646-xhx9pzhj 3039 7 47.1 47.1 CD cord-005646-xhx9pzhj 3039 8 ) ) -RRB- cord-005646-xhx9pzhj 3039 9 than than IN cord-005646-xhx9pzhj 3039 10 patients patient NNS cord-005646-xhx9pzhj 3039 11 with with IN cord-005646-xhx9pzhj 3039 12 ARDS ARDS NNP cord-005646-xhx9pzhj 3039 13 ( ( -LRB- cord-005646-xhx9pzhj 3039 14 43.4 43.4 CD cord-005646-xhx9pzhj 3039 15 ± ± CD cord-005646-xhx9pzhj 3039 16 50.8 50.8 CD cord-005646-xhx9pzhj 3039 17 ) ) -RRB- cord-005646-xhx9pzhj 3039 18 , , , cord-005646-xhx9pzhj 3039 19 ( ( -LRB- cord-005646-xhx9pzhj 3039 20 N.S N.S NNP cord-005646-xhx9pzhj 3039 21 ) ) -RRB- cord-005646-xhx9pzhj 3039 22 , , , cord-005646-xhx9pzhj 3039 23 but but CC cord-005646-xhx9pzhj 3039 24 patients patient NNS cord-005646-xhx9pzhj 3039 25 with with IN cord-005646-xhx9pzhj 3039 26 ARDS ARDS NNP cord-005646-xhx9pzhj 3039 27 showed show VBD cord-005646-xhx9pzhj 3039 28 a a DT cord-005646-xhx9pzhj 3039 29 higher high JJR cord-005646-xhx9pzhj 3039 30 increase increase NN cord-005646-xhx9pzhj 3039 31 in in IN cord-005646-xhx9pzhj 3039 32 0 0 CD cord-005646-xhx9pzhj 3039 33 ! ! . cord-005646-xhx9pzhj 3039 34 , , , cord-005646-xhx9pzhj 3039 35 15 15 CD cord-005646-xhx9pzhj 3039 36 ± ± CD cord-005646-xhx9pzhj 3039 37 6.7 6.7 CD cord-005646-xhx9pzhj 3039 38 , , , cord-005646-xhx9pzhj 3039 39 than than IN cord-005646-xhx9pzhj 3039 40 patients patient NNS cord-005646-xhx9pzhj 3039 41 with with IN cord-005646-xhx9pzhj 3039 42 PHT PHT NNP cord-005646-xhx9pzhj 3039 43 4.8 4.8 CD cord-005646-xhx9pzhj 3039 44 ± ± CD cord-005646-xhx9pzhj 3039 45 4 4 CD cord-005646-xhx9pzhj 3040 1 ( ( -LRB- cord-005646-xhx9pzhj 3040 2 p p NN cord-005646-xhx9pzhj 3040 3 < < XX cord-005646-xhx9pzhj 3040 4 0.05 0.05 CD cord-005646-xhx9pzhj 3040 5 ) ) -RRB- cord-005646-xhx9pzhj 3040 6 . . . cord-005646-xhx9pzhj 3041 1 Patients patient NNS cord-005646-xhx9pzhj 3041 2 with with IN cord-005646-xhx9pzhj 3041 3 Pa02 Pa02 NNP cord-005646-xhx9pzhj 3041 4 / / SYM cord-005646-xhx9pzhj 3041 5 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3041 6 < < XX cord-005646-xhx9pzhj 3041 7 I00 I00 NNP cord-005646-xhx9pzhj 3041 8 showed show VBD cord-005646-xhx9pzhj 3041 9 less less JJR cord-005646-xhx9pzhj 3041 10 increase increase NN cord-005646-xhx9pzhj 3041 11 in in IN cord-005646-xhx9pzhj 3041 12 Pa02 Pa02 NNP cord-005646-xhx9pzhj 3041 13 / / SYM cord-005646-xhx9pzhj 3041 14 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3041 15 , , , cord-005646-xhx9pzhj 3041 16 47.8 47.8 CD cord-005646-xhx9pzhj 3041 17 ± ± CD cord-005646-xhx9pzhj 3041 18 46.3 46.3 CD cord-005646-xhx9pzhj 3041 19 , , , cord-005646-xhx9pzhj 3041 20 than than IN cord-005646-xhx9pzhj 3041 21 the the DT cord-005646-xhx9pzhj 3041 22 rest rest NN cord-005646-xhx9pzhj 3041 23 of of IN cord-005646-xhx9pzhj 3041 24 patients patient NNS cord-005646-xhx9pzhj 3041 25 82.8 82.8 CD cord-005646-xhx9pzhj 3041 26 ± ± NNP cord-005646-xhx9pzhj 3041 27 65.5 65.5 CD cord-005646-xhx9pzhj 3041 28 ( ( -LRB- cord-005646-xhx9pzhj 3041 29 N.S N.S NNP cord-005646-xhx9pzhj 3041 30 ) ) -RRB- cord-005646-xhx9pzhj 3042 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3042 2 : : : cord-005646-xhx9pzhj 3043 1 i. i. LS cord-005646-xhx9pzhj 3043 2 Mortality mortality NN cord-005646-xhx9pzhj 3043 3 of of IN cord-005646-xhx9pzhj 3043 4 isolated isolate VBN cord-005646-xhx9pzhj 3043 5 PHT PHT NNP cord-005646-xhx9pzhj 3043 6 treated treat VBN cord-005646-xhx9pzhj 3043 7 with with IN cord-005646-xhx9pzhj 3043 8 NO no DT cord-005646-xhx9pzhj 3043 9 is be VBZ cord-005646-xhx9pzhj 3043 10 less less JJR cord-005646-xhx9pzhj 3043 11 than than IN cord-005646-xhx9pzhj 3043 12 patients patient NNS cord-005646-xhx9pzhj 3043 13 with with IN cord-005646-xhx9pzhj 3043 14 AP AP NNP cord-005646-xhx9pzhj 3043 15 ~ ~ NFP cord-005646-xhx9pzhj 3043 16 S. S. NNP cord-005646-xhx9pzhj 3043 17 Patients patient NNS cord-005646-xhx9pzhj 3043 18 with with IN cord-005646-xhx9pzhj 3043 19 shock shock NN cord-005646-xhx9pzhj 3043 20 and and CC cord-005646-xhx9pzhj 3043 21 those those DT cord-005646-xhx9pzhj 3043 22 with with IN cord-005646-xhx9pzhj 3043 23 PHT PHT NNP cord-005646-xhx9pzhj 3043 24 and and CC cord-005646-xhx9pzhj 3043 25 ARDS ARDS NNP cord-005646-xhx9pzhj 3043 26 showed show VBD cord-005646-xhx9pzhj 3043 27 higher high JJR cord-005646-xhx9pzhj 3043 28 mortality mortality NN cord-005646-xhx9pzhj 3043 29 . . . cord-005646-xhx9pzhj 3044 1 2 2 LS cord-005646-xhx9pzhj 3044 2 . . . cord-005646-xhx9pzhj 3045 1 We -PRON- PRP cord-005646-xhx9pzhj 3045 2 have have VBP cord-005646-xhx9pzhj 3045 3 not not RB cord-005646-xhx9pzhj 3045 4 found find VBN cord-005646-xhx9pzhj 3045 5 any any DT cord-005646-xhx9pzhj 3045 6 clinical clinical JJ cord-005646-xhx9pzhj 3045 7 or or CC cord-005646-xhx9pzhj 3045 8 analytical analytical JJ cord-005646-xhx9pzhj 3045 9 factor factor NN cord-005646-xhx9pzhj 3045 10 to to TO cord-005646-xhx9pzhj 3045 11 predict predict VB cord-005646-xhx9pzhj 3045 12 clinical clinical JJ cord-005646-xhx9pzhj 3045 13 response response NN cord-005646-xhx9pzhj 3045 14 to to IN cord-005646-xhx9pzhj 3045 15 NO no DT cord-005646-xhx9pzhj 3045 16 administration administration NN cord-005646-xhx9pzhj 3045 17 . . . cord-005646-xhx9pzhj 3046 1 14 14 CD cord-005646-xhx9pzhj 3046 2 patients patient NNS cord-005646-xhx9pzhj 3046 3 showed show VBD cord-005646-xhx9pzhj 3046 4 ARDS ARDS NNP cord-005646-xhx9pzhj 3046 5 , , , cord-005646-xhx9pzhj 3046 6 and and CC cord-005646-xhx9pzhj 3046 7 9 9 CD cord-005646-xhx9pzhj 3046 8 severe severe JJ cord-005646-xhx9pzhj 3046 9 PHT PHT NNP cord-005646-xhx9pzhj 3046 10 after after IN cord-005646-xhx9pzhj 3046 11 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 3046 12 surgery surgery NN cord-005646-xhx9pzhj 3046 13 , , , cord-005646-xhx9pzhj 3046 14 in in IN cord-005646-xhx9pzhj 3046 15 5 5 CD cord-005646-xhx9pzhj 3046 16 with with IN cord-005646-xhx9pzhj 3046 17 associated associate VBN cord-005646-xhx9pzhj 3046 18 ARDS ARDS NNP cord-005646-xhx9pzhj 3046 19 . . . cord-005646-xhx9pzhj 3047 1 We -PRON- PRP cord-005646-xhx9pzhj 3047 2 registered register VBD cord-005646-xhx9pzhj 3047 3 respiratory respiratory JJ cord-005646-xhx9pzhj 3047 4 assistance assistance NN cord-005646-xhx9pzhj 3047 5 , , , cord-005646-xhx9pzhj 3047 6 blood blood NN cord-005646-xhx9pzhj 3047 7 gases gas NNS cord-005646-xhx9pzhj 3047 8 , , , cord-005646-xhx9pzhj 3047 9 PaO2 PaO2 NNS cord-005646-xhx9pzhj 3047 10 / / SYM cord-005646-xhx9pzhj 3047 11 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3047 12 , , , cord-005646-xhx9pzhj 3047 13 the the DT cord-005646-xhx9pzhj 3047 14 oxygenation oxygenation NN cord-005646-xhx9pzhj 3047 15 index index NN cord-005646-xhx9pzhj 3047 16 ( ( -LRB- cord-005646-xhx9pzhj 3047 17 Oil oil NN cord-005646-xhx9pzhj 3047 18 , , , cord-005646-xhx9pzhj 3047 19 and and CC cord-005646-xhx9pzhj 3047 20 mean mean VB cord-005646-xhx9pzhj 3047 21 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3048 1 pressure/ pressure/ CD cord-005646-xhx9pzhj 3048 2 mean mean VBP cord-005646-xhx9pzhj 3048 3 systemic systemic JJ cord-005646-xhx9pzhj 3048 4 pressure pressure NN cord-005646-xhx9pzhj 3049 1 ( ( -LRB- cord-005646-xhx9pzhj 3049 2 PAP PAP NNP cord-005646-xhx9pzhj 3049 3 / / SYM cord-005646-xhx9pzhj 3049 4 SAP SAP NNP cord-005646-xhx9pzhj 3049 5 ) ) -RRB- cord-005646-xhx9pzhj 3049 6 before before IN cord-005646-xhx9pzhj 3049 7 and and CC cord-005646-xhx9pzhj 3049 8 after after IN cord-005646-xhx9pzhj 3049 9 NO no DT cord-005646-xhx9pzhj 3049 10 inhalation inhalation NN cord-005646-xhx9pzhj 3049 11 . . . cord-005646-xhx9pzhj 3050 1 We -PRON- PRP cord-005646-xhx9pzhj 3050 2 measured measure VBD cord-005646-xhx9pzhj 3050 3 continuous continuous JJ cord-005646-xhx9pzhj 3050 4 concentration concentration NN cord-005646-xhx9pzhj 3050 5 of of IN cord-005646-xhx9pzhj 3050 6 NO NO NNP cord-005646-xhx9pzhj 3050 7 and and CC cord-005646-xhx9pzhj 3050 8 NO2 NO2 NNP cord-005646-xhx9pzhj 3050 9 by by IN cord-005646-xhx9pzhj 3050 10 electrochemical electrochemical JJ cord-005646-xhx9pzhj 3050 11 method method NN cord-005646-xhx9pzhj 3050 12 ( ( -LRB- cord-005646-xhx9pzhj 3050 13 NoxBOX NoxBOX NNP cord-005646-xhx9pzhj 3050 14 , , , cord-005646-xhx9pzhj 3050 15 Bedfont Bedfont NNP cord-005646-xhx9pzhj 3050 16 , , , cord-005646-xhx9pzhj 3050 17 Airliquide Airliquide NNP cord-005646-xhx9pzhj 3050 18 ) ) -RRB- cord-005646-xhx9pzhj 3050 19 . . . cord-005646-xhx9pzhj 3051 1 Results result NNS cord-005646-xhx9pzhj 3051 2 : : : cord-005646-xhx9pzhj 3052 1 NO no DT cord-005646-xhx9pzhj 3052 2 administration administration NN cord-005646-xhx9pzhj 3052 3 improved improve VBD cord-005646-xhx9pzhj 3052 4 oxygenation oxygenation NN cord-005646-xhx9pzhj 3052 5 mean mean VBP cord-005646-xhx9pzhj 3052 6 PaO2 PaO2 NNS cord-005646-xhx9pzhj 3052 7 from from IN cord-005646-xhx9pzhj 3052 8 74 74 CD cord-005646-xhx9pzhj 3053 1 ± ± NNP cord-005646-xhx9pzhj 3053 2 17 17 CD cord-005646-xhx9pzhj 3054 1 Tm Tm NNP cord-005646-xhx9pzhj 3055 1 ~g ~g NNP cord-005646-xhx9pzhj 3055 2 to to IN cord-005646-xhx9pzhj 3055 3 i19 i19 NN cord-005646-xhx9pzhj 3055 4 ± ± CD cord-005646-xhx9pzhj 3055 5 54 54 CD cord-005646-xhx9pzhj 3056 1 ~g ~g NNP cord-005646-xhx9pzhj 3057 1 ( ( -LRB- cord-005646-xhx9pzhj 3057 2 p p NN cord-005646-xhx9pzhj 3057 3 < < XX cord-005646-xhx9pzhj 3057 4 0.01 0.01 CD cord-005646-xhx9pzhj 3057 5 ) ) -RRB- cord-005646-xhx9pzhj 3058 1 , , , cord-005646-xhx9pzhj 3058 2 mean mean VB cord-005646-xhx9pzhj 3058 3 Pa02/ pa02/ NN cord-005646-xhx9pzhj 3059 1 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3060 1 fr fr NNP cord-005646-xhx9pzhj 3060 2 < < NNP cord-005646-xhx9pzhj 3060 3 xa xa NNP cord-005646-xhx9pzhj 3060 4 83 83 CD cord-005646-xhx9pzhj 3060 5 ~ ~ CD cord-005646-xhx9pzhj 3060 6 30 30 CD cord-005646-xhx9pzhj 3060 7 to to TO cord-005646-xhx9pzhj 3060 8 13£± 13£± CD cord-005646-xhx9pzhj 3060 9 72 72 CD cord-005646-xhx9pzhj 3061 1 ( ( -LRB- cord-005646-xhx9pzhj 3061 2 p p NN cord-005646-xhx9pzhj 3061 3 < < XX cord-005646-xhx9pzhj 3061 4 0.01)and 0.01)and CD cord-005646-xhx9pzhj 3061 5 0i 0i CD cord-005646-xhx9pzhj 3061 6 from from IN cord-005646-xhx9pzhj 3061 7 28 28 CD cord-005646-xhx9pzhj 3061 8 ± ± CD cord-005646-xhx9pzhj 3061 9 14 14 CD cord-005646-xhx9pzhj 3061 10 to to TO cord-005646-xhx9pzhj 3061 11 20 20 CD cord-005646-xhx9pzhj 3061 12 ± ± CD cord-005646-xhx9pzhj 3061 13 12 12 CD cord-005646-xhx9pzhj 3062 1 ( ( -LRB- cord-005646-xhx9pzhj 3062 2 p p NN cord-005646-xhx9pzhj 3062 3 < < XX cord-005646-xhx9pzhj 3062 4 0.01 0.01 CD cord-005646-xhx9pzhj 3062 5 ) ) -RRB- cord-005646-xhx9pzhj 3062 6 . . . cord-005646-xhx9pzhj 3063 1 2 2 CD cord-005646-xhx9pzhj 3063 2 patients patient NNS cord-005646-xhx9pzhj 3063 3 did do VBD cord-005646-xhx9pzhj 3063 4 not not RB cord-005646-xhx9pzhj 3063 5 improved improve VBN cord-005646-xhx9pzhj 3063 6 with with IN cord-005646-xhx9pzhj 3063 7 NO no DT cord-005646-xhx9pzhj 3063 8 administration administration NN cord-005646-xhx9pzhj 3063 9 . . . cord-005646-xhx9pzhj 3064 1 The the DT cord-005646-xhx9pzhj 3064 2 Oxygenation oxygenation NN cord-005646-xhx9pzhj 3064 3 improved improve VBD cord-005646-xhx9pzhj 3064 4 in in IN cord-005646-xhx9pzhj 3064 5 the the DT cord-005646-xhx9pzhj 3064 6 first first JJ cord-005646-xhx9pzhj 3064 7 five five CD cord-005646-xhx9pzhj 3064 8 minutes minute NNS cord-005646-xhx9pzhj 3064 9 and and CC cord-005646-xhx9pzhj 3064 10 the the DT cord-005646-xhx9pzhj 3064 11 best good JJS cord-005646-xhx9pzhj 3064 12 oxygenation oxygenation NN cord-005646-xhx9pzhj 3064 13 was be VBD cord-005646-xhx9pzhj 3064 14 achieved achieve VBN cord-005646-xhx9pzhj 3064 15 with with IN cord-005646-xhx9pzhj 3064 16 5 5 CD cord-005646-xhx9pzhj 3064 17 -15 -15 CD cord-005646-xhx9pzhj 3064 18 ppm ppm NN cord-005646-xhx9pzhj 3064 19 . . . cord-005646-xhx9pzhj 3065 1 There there EX cord-005646-xhx9pzhj 3065 2 is be VBZ cord-005646-xhx9pzhj 3065 3 no no DT cord-005646-xhx9pzhj 3065 4 significant significant JJ cord-005646-xhx9pzhj 3065 5 change change NN cord-005646-xhx9pzhj 3065 6 in in IN cord-005646-xhx9pzhj 3065 7 PaC02 PaC02 NNP cord-005646-xhx9pzhj 3065 8 . . . cord-005646-xhx9pzhj 3066 1 PAP PAP NNP cord-005646-xhx9pzhj 3066 2 / / SYM cord-005646-xhx9pzhj 3066 3 SAP SAP NNP cord-005646-xhx9pzhj 3066 4 diminished diminish VBD cord-005646-xhx9pzhj 3066 5 from from IN cord-005646-xhx9pzhj 3066 6 62 62 CD cord-005646-xhx9pzhj 3066 7 ± ± CD cord-005646-xhx9pzhj 3066 8 17 17 CD cord-005646-xhx9pzhj 3066 9 % % NN cord-005646-xhx9pzhj 3066 10 to to IN cord-005646-xhx9pzhj 3066 11 42 42 CD cord-005646-xhx9pzhj 3066 12 ± ± CD cord-005646-xhx9pzhj 3066 13 9 9 CD cord-005646-xhx9pzhj 3066 14 % % NN cord-005646-xhx9pzhj 3066 15 ( ( -LRB- cord-005646-xhx9pzhj 3066 16 p p NN cord-005646-xhx9pzhj 3066 17 < < XX cord-005646-xhx9pzhj 3066 18 0.05 0.05 CD cord-005646-xhx9pzhj 3066 19 ) ) -RRB- cord-005646-xhx9pzhj 3066 20 , , , cord-005646-xhx9pzhj 3066 21 In in IN cord-005646-xhx9pzhj 3066 22 one one CD cord-005646-xhx9pzhj 3066 23 patient patient NN cord-005646-xhx9pzhj 3066 24 there there EX cord-005646-xhx9pzhj 3066 25 is be VBZ cord-005646-xhx9pzhj 3066 26 no no DT cord-005646-xhx9pzhj 3066 27 response response NN cord-005646-xhx9pzhj 3066 28 . . . cord-005646-xhx9pzhj 3067 1 The the DT cord-005646-xhx9pzhj 3067 2 NO NO NNP cord-005646-xhx9pzhj 3067 3 administration administration NN cord-005646-xhx9pzhj 3067 4 was be VBD cord-005646-xhx9pzhj 3067 5 maintained maintain VBN cord-005646-xhx9pzhj 3067 6 between between IN cord-005646-xhx9pzhj 3067 7 ~5 ~5 CD cord-005646-xhx9pzhj 3067 8 minutes minute NNS cord-005646-xhx9pzhj 3067 9 to to IN cord-005646-xhx9pzhj 3067 10 47 47 CD cord-005646-xhx9pzhj 3067 11 days day NNS cord-005646-xhx9pzhj 3067 12 . . . cord-005646-xhx9pzhj 3068 1 The the DT cord-005646-xhx9pzhj 3068 2 effect effect NN cord-005646-xhx9pzhj 3068 3 of of IN cord-005646-xhx9pzhj 3068 4 NO no DT cord-005646-xhx9pzhj 3068 5 on on IN cord-005646-xhx9pzhj 3068 6 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3068 7 pressure pressure NN cord-005646-xhx9pzhj 3068 8 and and CC cord-005646-xhx9pzhj 3068 9 oxygenation oxygenation NN cord-005646-xhx9pzhj 3068 10 was be VBD cord-005646-xhx9pzhj 3068 11 maintained maintain VBN cord-005646-xhx9pzhj 3068 12 without without IN cord-005646-xhx9pzhj 3068 13 change change NN cord-005646-xhx9pzhj 3068 14 during during IN cord-005646-xhx9pzhj 3068 15 all all PDT cord-005646-xhx9pzhj 3068 16 the the DT cord-005646-xhx9pzhj 3068 17 time time NN cord-005646-xhx9pzhj 3068 18 it -PRON- PRP cord-005646-xhx9pzhj 3068 19 was be VBD cord-005646-xhx9pzhj 3068 20 administrated administrate VBN cord-005646-xhx9pzhj 3068 21 . . . cord-005646-xhx9pzhj 3069 1 N02 n02 JJ cord-005646-xhx9pzhj 3069 2 concentration concentration NN cord-005646-xhx9pzhj 3069 3 were be VBD cord-005646-xhx9pzhj 3069 4 always always RB cord-005646-xhx9pzhj 3069 5 less less JJR cord-005646-xhx9pzhj 3069 6 than than IN cord-005646-xhx9pzhj 3069 7 2 2 CD cord-005646-xhx9pzhj 3069 8 ppm ppm NN cord-005646-xhx9pzhj 3070 1 y y NNP cord-005646-xhx9pzhj 3070 2 metahemoglobinaemia metahemoglobinaemia NNP cord-005646-xhx9pzhj 3070 3 less less JJR cord-005646-xhx9pzhj 3070 4 than than IN cord-005646-xhx9pzhj 3070 5 3.5 3.5 CD cord-005646-xhx9pzhj 3070 6 % % NN cord-005646-xhx9pzhj 3070 7 . . . cord-005646-xhx9pzhj 3071 1 There there EX cord-005646-xhx9pzhj 3071 2 are be VBP cord-005646-xhx9pzhj 3071 3 no no DT cord-005646-xhx9pzhj 3071 4 side side NN cord-005646-xhx9pzhj 3071 5 effects effect NNS cord-005646-xhx9pzhj 3071 6 secondary secondary JJ cord-005646-xhx9pzhj 3071 7 to to IN cord-005646-xhx9pzhj 3071 8 NO no DT cord-005646-xhx9pzhj 3071 9 administration administration NN cord-005646-xhx9pzhj 3071 10 . . . cord-005646-xhx9pzhj 3072 1 12 12 CD cord-005646-xhx9pzhj 3072 2 patients patient NNS cord-005646-xhx9pzhj 3072 3 survived survive VBD cord-005646-xhx9pzhj 3072 4 ( ( -LRB- cord-005646-xhx9pzhj 3072 5 52 52 CD cord-005646-xhx9pzhj 3072 6 % % NN cord-005646-xhx9pzhj 3072 7 ) ) -RRB- cord-005646-xhx9pzhj 3072 8 . . . cord-005646-xhx9pzhj 3073 1 Concluaions concluaion NNS cord-005646-xhx9pzhj 3073 2 : : : cord-005646-xhx9pzhj 3074 1 l. l. NNP cord-005646-xhx9pzhj 3075 1 Administration administration NN cord-005646-xhx9pzhj 3075 2 of of IN cord-005646-xhx9pzhj 3075 3 NO no DT cord-005646-xhx9pzhj 3075 4 improves improve VBZ cord-005646-xhx9pzhj 3075 5 oxygenation oxygenation NN cord-005646-xhx9pzhj 3075 6 in in IN cord-005646-xhx9pzhj 3075 7 children child NNS cord-005646-xhx9pzhj 3075 8 with with IN cord-005646-xhx9pzhj 3075 9 ~/EDS ~/eds NN cord-005646-xhx9pzhj 3075 10 and and CC cord-005646-xhx9pzhj 3075 11 diminishes diminish VBZ cord-005646-xhx9pzhj 3075 12 PHT PHT NNP cord-005646-xhx9pzhj 3075 13 after after IN cord-005646-xhx9pzhj 3075 14 cardiac cardiac JJ cord-005646-xhx9pzhj 3075 15 surgery surgery NN cord-005646-xhx9pzhj 3075 16 . . . cord-005646-xhx9pzhj 3076 1 2.NO 2.no CD cord-005646-xhx9pzhj 3076 2 effect effect NN cord-005646-xhx9pzhj 3076 3 is be VBZ cord-005646-xhx9pzhj 3076 4 fast fast JJ cord-005646-xhx9pzhj 3076 5 and and CC cord-005646-xhx9pzhj 3076 6 maintained maintain VBN cord-005646-xhx9pzhj 3076 7 during during IN cord-005646-xhx9pzhj 3076 8 the the DT cord-005646-xhx9pzhj 3076 9 evolution evolution NN cord-005646-xhx9pzhj 3076 10 . . . cord-005646-xhx9pzhj 3077 1 High high JJ cord-005646-xhx9pzhj 3077 2 Frequency Frequency NNP cord-005646-xhx9pzhj 3077 3 Oscillatory Oscillatory NNP cord-005646-xhx9pzhj 3077 4 Ventilation Ventilation NNP cord-005646-xhx9pzhj 3077 5 in in IN cord-005646-xhx9pzhj 3077 6 Combination combination NN cord-005646-xhx9pzhj 3077 7 with with IN cord-005646-xhx9pzhj 3077 8 Inhaled Inhaled NNP cord-005646-xhx9pzhj 3077 9 Nitric nitric NN cord-005646-xhx9pzhj 3077 10 Oxide oxide NN cord-005646-xhx9pzhj 3077 11 G g NN cord-005646-xhx9pzhj 3077 12 ~ ~ NFP cord-005646-xhx9pzhj 3077 13 thberg thberg NNP cord-005646-xhx9pzhj 3077 14 Sylvia Sylvia NNP cord-005646-xhx9pzhj 3077 15 , , , cord-005646-xhx9pzhj 3077 16 MD MD NNP cord-005646-xhx9pzhj 3077 17 , , , cord-005646-xhx9pzhj 3077 18 Edberg Edberg NNP cord-005646-xhx9pzhj 3077 19 K K NNP cord-005646-xhx9pzhj 3077 20 E E NNP cord-005646-xhx9pzhj 3077 21 MD MD NNP cord-005646-xhx9pzhj 3077 22 , , , cord-005646-xhx9pzhj 3077 23 Phi Phi NNP cord-005646-xhx9pzhj 3077 24 ) ) -RRB- cord-005646-xhx9pzhj 3077 25 , , , cord-005646-xhx9pzhj 3077 26 Dept Dept NNP cord-005646-xhx9pzhj 3077 27 of of IN cord-005646-xhx9pzhj 3077 28 Paediatric Paediatric NNP cord-005646-xhx9pzhj 3077 29 Intensive Intensive NNP cord-005646-xhx9pzhj 3077 30 Care Care NNP cord-005646-xhx9pzhj 3077 31 , , , cord-005646-xhx9pzhj 3077 32 Children Children NNP cord-005646-xhx9pzhj 3077 33 's 's POS cord-005646-xhx9pzhj 3077 34 Hospital Hospital NNP cord-005646-xhx9pzhj 3077 35 , , , cord-005646-xhx9pzhj 3078 1 S-416 S-416 NNP cord-005646-xhx9pzhj 3078 2 85 85 CD cord-005646-xhx9pzhj 3078 3 G6teborg g6teborg NN cord-005646-xhx9pzhj 3078 4 , , , cord-005646-xhx9pzhj 3078 5 Sweden Sweden NNP cord-005646-xhx9pzhj 3078 6 Background Background NNP cord-005646-xhx9pzhj 3078 7 : : : cord-005646-xhx9pzhj 3079 1 For for IN cord-005646-xhx9pzhj 3079 2 man man NN cord-005646-xhx9pzhj 3079 3 ) ) -RRB- cord-005646-xhx9pzhj 3079 4 , , , cord-005646-xhx9pzhj 3079 5 years year NNS cord-005646-xhx9pzhj 3079 6 severely severely RB cord-005646-xhx9pzhj 3079 7 sick sick JJ cord-005646-xhx9pzhj 3079 8 infants infant NNS cord-005646-xhx9pzhj 3079 9 with with IN cord-005646-xhx9pzhj 3079 10 congenital congenital JJ cord-005646-xhx9pzhj 3079 11 heart heart NN cord-005646-xhx9pzhj 3079 12 malformations malformation NNS cord-005646-xhx9pzhj 3079 13 or or CC cord-005646-xhx9pzhj 3079 14 acute acute JJ cord-005646-xhx9pzhj 3079 15 lung lung NN cord-005646-xhx9pzhj 3079 16 disorders disorder NNS cord-005646-xhx9pzhj 3079 17 have have VBP cord-005646-xhx9pzhj 3079 18 died die VBN cord-005646-xhx9pzhj 3079 19 due due IN cord-005646-xhx9pzhj 3079 20 to to IN cord-005646-xhx9pzhj 3079 21 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3079 22 hypertension hypertension NN cord-005646-xhx9pzhj 3079 23 , , , cord-005646-xhx9pzhj 3079 24 hypoxia hypoxia NN cord-005646-xhx9pzhj 3079 25 and and CC cord-005646-xhx9pzhj 3079 26 multiple multiple JJ cord-005646-xhx9pzhj 3079 27 organ organ NN cord-005646-xhx9pzhj 3079 28 failure failure NN cord-005646-xhx9pzhj 3079 29 . . . cord-005646-xhx9pzhj 3080 1 Today today NN cord-005646-xhx9pzhj 3080 2 there there EX cord-005646-xhx9pzhj 3080 3 are be VBP cord-005646-xhx9pzhj 3080 4 several several JJ cord-005646-xhx9pzhj 3080 5 therapeutic therapeutic JJ cord-005646-xhx9pzhj 3080 6 facilities facility NNS cord-005646-xhx9pzhj 3080 7 coming come VBG cord-005646-xhx9pzhj 3080 8 up up RP cord-005646-xhx9pzhj 3080 9 for for IN cord-005646-xhx9pzhj 3080 10 these these DT cord-005646-xhx9pzhj 3080 11 infants infant NNS cord-005646-xhx9pzhj 3080 12 . . . cord-005646-xhx9pzhj 3081 1 ECMO ECMO NNP cord-005646-xhx9pzhj 3081 2 progranunes progranune NNS cord-005646-xhx9pzhj 3081 3 have have VBP cord-005646-xhx9pzhj 3081 4 been be VBN cord-005646-xhx9pzhj 3081 5 introduced introduce VBN cord-005646-xhx9pzhj 3081 6 in in IN cord-005646-xhx9pzhj 3081 7 severul severul NNP cord-005646-xhx9pzhj 3081 8 centres centre NNS cord-005646-xhx9pzhj 3081 9 as as RB cord-005646-xhx9pzhj 3081 10 well well RB cord-005646-xhx9pzhj 3081 11 as as IN cord-005646-xhx9pzhj 3081 12 improved improve VBN cord-005646-xhx9pzhj 3081 13 venlllatory venlllatory NN cord-005646-xhx9pzhj 3081 14 techniques technique NNS cord-005646-xhx9pzhj 3081 15 , , , cord-005646-xhx9pzhj 3081 16 as as IN cord-005646-xhx9pzhj 3081 17 high high JJ cord-005646-xhx9pzhj 3081 18 frequency frequency NN cord-005646-xhx9pzhj 3081 19 oscillatory oscillatory JJ cord-005646-xhx9pzhj 3081 20 ventilatior~ ventilatior~ NN cord-005646-xhx9pzhj 3081 21 ( ( -LRB- cord-005646-xhx9pzhj 3081 22 HFOV HFOV NNP cord-005646-xhx9pzhj 3081 23 ) ) -RRB- cord-005646-xhx9pzhj 3081 24 , , , cord-005646-xhx9pzhj 3081 25 which which WDT cord-005646-xhx9pzhj 3081 26 provides provide VBZ cord-005646-xhx9pzhj 3081 27 adequate adequate JJ cord-005646-xhx9pzhj 3081 28 ventilation ventilation NN cord-005646-xhx9pzhj 3081 29 with with IN cord-005646-xhx9pzhj 3081 30 less less JJR cord-005646-xhx9pzhj 3081 31 risk risk NN cord-005646-xhx9pzhj 3081 32 for for IN cord-005646-xhx9pzhj 3081 33 hmg hmg NNP cord-005646-xhx9pzhj 3081 34 injury injury NN cord-005646-xhx9pzhj 3081 35 .. .. . cord-005646-xhx9pzhj 3082 1 In in IN cord-005646-xhx9pzhj 3082 2 1987 1987 CD cord-005646-xhx9pzhj 3082 3 , , , cord-005646-xhx9pzhj 3082 4 the the DT cord-005646-xhx9pzhj 3082 5 endothelium endothelium NN cord-005646-xhx9pzhj 3082 6 derived derive VBN cord-005646-xhx9pzhj 3082 7 relaxing relax VBG cord-005646-xhx9pzhj 3082 8 factor factor NN cord-005646-xhx9pzhj 3082 9 was be VBD cord-005646-xhx9pzhj 3082 10 identified identify VBN cord-005646-xhx9pzhj 3082 11 as as IN cord-005646-xhx9pzhj 3082 12 nitric nitric JJ cord-005646-xhx9pzhj 3082 13 oxide oxide NN cord-005646-xhx9pzhj 3082 14 ( ( -LRB- cord-005646-xhx9pzhj 3082 15 NO no UH cord-005646-xhx9pzhj 3082 16 ) ) -RRB- cord-005646-xhx9pzhj 3082 17 , , , cord-005646-xhx9pzhj 3082 18 and and CC cord-005646-xhx9pzhj 3082 19 extensive extensive JJ cord-005646-xhx9pzhj 3082 20 studies study NNS cord-005646-xhx9pzhj 3082 21 have have VBP cord-005646-xhx9pzhj 3082 22 sho~-a sho~-a CD cord-005646-xhx9pzhj 3082 23 that that WDT cord-005646-xhx9pzhj 3082 24 inhaled inhale VBD cord-005646-xhx9pzhj 3082 25 NO no DT cord-005646-xhx9pzhj 3082 26 reduces reduce VBZ cord-005646-xhx9pzhj 3083 1 pnimonm3 pnimonm3 NNP cord-005646-xhx9pzhj 3083 2 o o NNP cord-005646-xhx9pzhj 3083 3 vascular vascular JJ cord-005646-xhx9pzhj 3083 4 resistance resistance NN cord-005646-xhx9pzhj 3083 5 and and CC cord-005646-xhx9pzhj 3083 6 improves improve VBZ cord-005646-xhx9pzhj 3083 7 oxygenation oxygenation NN cord-005646-xhx9pzhj 3083 8 in in IN cord-005646-xhx9pzhj 3083 9 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3083 10 infants infant NNS cord-005646-xhx9pzhj 3083 11 with with IN cord-005646-xhx9pzhj 3083 12 pulmona~ pulmona~ NNS cord-005646-xhx9pzhj 3083 13 hypertension hypertension NN cord-005646-xhx9pzhj 3083 14 . . . cord-005646-xhx9pzhj 3084 1 Material material NN cord-005646-xhx9pzhj 3084 2 .. .. . cord-005646-xhx9pzhj 3085 1 From from IN cord-005646-xhx9pzhj 3085 2 July July NNP cord-005646-xhx9pzhj 3085 3 1994 1994 CD cord-005646-xhx9pzhj 3085 4 to to IN cord-005646-xhx9pzhj 3085 5 January January NNP cord-005646-xhx9pzhj 3085 6 1996 1996 CD cord-005646-xhx9pzhj 3085 7 , , , cord-005646-xhx9pzhj 3085 8 we -PRON- PRP cord-005646-xhx9pzhj 3085 9 have have VBP cord-005646-xhx9pzhj 3085 10 treated treat VBN cord-005646-xhx9pzhj 3085 11 13 13 CD cord-005646-xhx9pzhj 3085 12 severely severely RB cord-005646-xhx9pzhj 3085 13 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3085 14 children child NNS cord-005646-xhx9pzhj 3085 15 with with IN cord-005646-xhx9pzhj 3085 16 combined combine VBN cord-005646-xhx9pzhj 3085 17 ttFOV ttfov CD cord-005646-xhx9pzhj 3086 1 -NO -NO NNP cord-005646-xhx9pzhj 3086 2 . . . cord-005646-xhx9pzhj 3087 1 Seven seven CD cord-005646-xhx9pzhj 3087 2 were be VBD cord-005646-xhx9pzhj 3087 3 newborn newborn JJ cord-005646-xhx9pzhj 3087 4 , , , cord-005646-xhx9pzhj 3087 5 3 3 CD cord-005646-xhx9pzhj 3087 6 with with IN cord-005646-xhx9pzhj 3087 7 CDH CDH NNP cord-005646-xhx9pzhj 3087 8 , , , cord-005646-xhx9pzhj 3087 9 one one CD cord-005646-xhx9pzhj 3087 10 with with IN cord-005646-xhx9pzhj 3087 11 MAS MAS NNP cord-005646-xhx9pzhj 3087 12 , , , cord-005646-xhx9pzhj 3087 13 one one CD cord-005646-xhx9pzhj 3087 14 with with IN cord-005646-xhx9pzhj 3087 15 IRDS IRDS NNP cord-005646-xhx9pzhj 3087 16 , , , cord-005646-xhx9pzhj 3087 17 one one CD cord-005646-xhx9pzhj 3087 18 with with IN cord-005646-xhx9pzhj 3087 19 paediatric paediatric JJ cord-005646-xhx9pzhj 3087 20 ARDS ARDS NNP cord-005646-xhx9pzhj 3087 21 due due IN cord-005646-xhx9pzhj 3087 22 to to IN cord-005646-xhx9pzhj 3087 23 RSV RSV NNP cord-005646-xhx9pzhj 3087 24 infection infection NN cord-005646-xhx9pzhj 3087 25 and and CC cord-005646-xhx9pzhj 3087 26 one one CD cord-005646-xhx9pzhj 3087 27 with with IN cord-005646-xhx9pzhj 3087 28 poor poor JJ cord-005646-xhx9pzhj 3087 29 oxygenation oxygenation NN cord-005646-xhx9pzhj 3087 30 atler atler NN cord-005646-xhx9pzhj 3087 31 open open JJ cord-005646-xhx9pzhj 3087 32 heart heart NN cord-005646-xhx9pzhj 3087 33 surgery surgery NN cord-005646-xhx9pzhj 3087 34 . . . cord-005646-xhx9pzhj 3088 1 6 6 CD cord-005646-xhx9pzhj 3088 2 were be VBD cord-005646-xhx9pzhj 3088 3 between between IN cord-005646-xhx9pzhj 3088 4 1 1 CD cord-005646-xhx9pzhj 3088 5 month month NN cord-005646-xhx9pzhj 3088 6 and and CC cord-005646-xhx9pzhj 3088 7 9 9 CD cord-005646-xhx9pzhj 3088 8 years year NNS cord-005646-xhx9pzhj 3088 9 and and CC cord-005646-xhx9pzhj 3088 10 all all DT cord-005646-xhx9pzhj 3088 11 had have VBD cord-005646-xhx9pzhj 3088 12 ARDS ARDS NNP cord-005646-xhx9pzhj 3088 13 of of IN cord-005646-xhx9pzhj 3088 14 differentorigin differentorigin NNP cord-005646-xhx9pzhj 3088 15 but but CC cord-005646-xhx9pzhj 3088 16 one one CD cord-005646-xhx9pzhj 3088 17 who who WP cord-005646-xhx9pzhj 3088 18 was be VBD cord-005646-xhx9pzhj 3088 19 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3088 20 after after IN cord-005646-xhx9pzhj 3088 21 open open JJ cord-005646-xhx9pzhj 3088 22 heart heart NN cord-005646-xhx9pzhj 3088 23 surgery surgery NN cord-005646-xhx9pzhj 3088 24 . . . cord-005646-xhx9pzhj 3089 1 Method method NN cord-005646-xhx9pzhj 3089 2 : : : cord-005646-xhx9pzhj 3089 3 HFOV HFOV NNP cord-005646-xhx9pzhj 3089 4 was be VBD cord-005646-xhx9pzhj 3089 5 given give VBN cord-005646-xhx9pzhj 3089 6 by by IN cord-005646-xhx9pzhj 3089 7 means mean NNS cord-005646-xhx9pzhj 3089 8 of of IN cord-005646-xhx9pzhj 3089 9 SensorMedics SensorMedics NNP cord-005646-xhx9pzhj 3089 10 3100A 3100A NNP cord-005646-xhx9pzhj 3089 11 oscillatory oscillatory JJ cord-005646-xhx9pzhj 3089 12 ventilator ventilator NN cord-005646-xhx9pzhj 3089 13 to to IN cord-005646-xhx9pzhj 3089 14 12 12 CD cord-005646-xhx9pzhj 3089 15 patients patient NNS cord-005646-xhx9pzhj 3089 16 , , , cord-005646-xhx9pzhj 3089 17 and and CC cord-005646-xhx9pzhj 3089 18 Dr Dr NNP cord-005646-xhx9pzhj 3089 19 ~ ~ NFP cord-005646-xhx9pzhj 3089 20 ger ger NNP cord-005646-xhx9pzhj 3089 21 Babylog Babylog NNP cord-005646-xhx9pzhj 3089 22 8000 8000 CD cord-005646-xhx9pzhj 3089 23 was be VBD cord-005646-xhx9pzhj 3089 24 used use VBN cord-005646-xhx9pzhj 3089 25 in in IN cord-005646-xhx9pzhj 3089 26 one one CD cord-005646-xhx9pzhj 3089 27 case case NN cord-005646-xhx9pzhj 3089 28 . . . cord-005646-xhx9pzhj 3090 1 Mean mean JJ cord-005646-xhx9pzhj 3090 2 airway airway NN cord-005646-xhx9pzhj 3090 3 pwssures pwssure NNS cord-005646-xhx9pzhj 3090 4 varied vary VBN cord-005646-xhx9pzhj 3090 5 from from IN cord-005646-xhx9pzhj 3090 6 10 10 CD cord-005646-xhx9pzhj 3090 7 - - SYM cord-005646-xhx9pzhj 3090 8 34 34 CD cord-005646-xhx9pzhj 3090 9 cm cm NN cord-005646-xhx9pzhj 3090 10 H20 h20 NN cord-005646-xhx9pzhj 3090 11 . . . cord-005646-xhx9pzhj 3091 1 Oscillatory oscillatory JJ cord-005646-xhx9pzhj 3091 2 pressures pressure NNS cord-005646-xhx9pzhj 3091 3 varied vary VBN cord-005646-xhx9pzhj 3091 4 from from IN cord-005646-xhx9pzhj 3091 5 25 25 CD cord-005646-xhx9pzhj 3091 6 - - SYM cord-005646-xhx9pzhj 3091 7 85 85 CD cord-005646-xhx9pzhj 3091 8 cm cm NN cord-005646-xhx9pzhj 3091 9 H20 h20 NN cord-005646-xhx9pzhj 3091 10 and and CC cord-005646-xhx9pzhj 3091 11 ventilatory ventilatory JJ cord-005646-xhx9pzhj 3091 12 rates rate NNS cord-005646-xhx9pzhj 3091 13 from from IN cord-005646-xhx9pzhj 3091 14 6 6 CD cord-005646-xhx9pzhj 3091 15 - - SYM cord-005646-xhx9pzhj 3091 16 15 15 CD cord-005646-xhx9pzhj 3091 17 Hz Hz NNS cord-005646-xhx9pzhj 3091 18 . . . cord-005646-xhx9pzhj 3092 1 Fi Fi NNP cord-005646-xhx9pzhj 3092 2 O2 O2 NNP cord-005646-xhx9pzhj 3092 3 varied vary VBN cord-005646-xhx9pzhj 3092 4 from from IN cord-005646-xhx9pzhj 3092 5 0,21 0,21 CD cord-005646-xhx9pzhj 3092 6 -1,0 -1,0 NN cord-005646-xhx9pzhj 3092 7 . . . cord-005646-xhx9pzhj 3093 1 NO no UH cord-005646-xhx9pzhj 3093 2 was be VBD cord-005646-xhx9pzhj 3093 3 administered administer VBN cord-005646-xhx9pzhj 3093 4 by by IN cord-005646-xhx9pzhj 3093 5 NOMIUS NOMIUS NNP cord-005646-xhx9pzhj 3093 6 classic classic JJ cord-005646-xhx9pzhj 3093 7 . . . cord-005646-xhx9pzhj 3094 1 NO NO NNP cord-005646-xhx9pzhj 3094 2 and and CC cord-005646-xhx9pzhj 3094 3 NO2 NO2 NNP cord-005646-xhx9pzhj 3094 4 was be VBD cord-005646-xhx9pzhj 3094 5 measured measure VBN cord-005646-xhx9pzhj 3094 6 in in IN cord-005646-xhx9pzhj 3094 7 the the DT cord-005646-xhx9pzhj 3094 8 inspiratory inspiratory JJ cord-005646-xhx9pzhj 3094 9 limb limb NN cord-005646-xhx9pzhj 3094 10 with with IN cord-005646-xhx9pzhj 3094 11 an an DT cord-005646-xhx9pzhj 3094 12 electrcchemieal electrcchemieal NN cord-005646-xhx9pzhj 3094 13 device device NN cord-005646-xhx9pzhj 3094 14 . . . cord-005646-xhx9pzhj 3095 1 NOconcentration noconcentration NN cord-005646-xhx9pzhj 3095 2 varied varied JJ cord-005646-xhx9pzhj 3095 3 from from IN cord-005646-xhx9pzhj 3095 4 2 2 CD cord-005646-xhx9pzhj 3095 5 to to TO cord-005646-xhx9pzhj 3095 6 20 20 CD cord-005646-xhx9pzhj 3095 7 ppm ppm NN cord-005646-xhx9pzhj 3095 8 and and CC cord-005646-xhx9pzhj 3095 9 the the DT cord-005646-xhx9pzhj 3095 10 NO2 NO2 NNP cord-005646-xhx9pzhj 3095 11 -concentration -concentration NN cord-005646-xhx9pzhj 3095 12 between between IN cord-005646-xhx9pzhj 3095 13 0 0 CD cord-005646-xhx9pzhj 3095 14 - - HYPH cord-005646-xhx9pzhj 3095 15 0,2 0,2 CD cord-005646-xhx9pzhj 3095 16 ppm ppm NN cord-005646-xhx9pzhj 3095 17 . . . cord-005646-xhx9pzhj 3096 1 Methemoglobin Methemoglobin NNP cord-005646-xhx9pzhj 3096 2 was be VBD cord-005646-xhx9pzhj 3096 3 never never RB cord-005646-xhx9pzhj 3096 4 more more JJR cord-005646-xhx9pzhj 3096 5 than than IN cord-005646-xhx9pzhj 3096 6 3,7 3,7 CD cord-005646-xhx9pzhj 3096 7 % % NN cord-005646-xhx9pzhj 3096 8 ( ( -LRB- cord-005646-xhx9pzhj 3096 9 average average JJ cord-005646-xhx9pzhj 3096 10 1,7 1,7 CD cord-005646-xhx9pzhj 3096 11 ) ) -RRB- cord-005646-xhx9pzhj 3096 12 . . . cord-005646-xhx9pzhj 3097 1 Duration duration NN cord-005646-xhx9pzhj 3097 2 of of IN cord-005646-xhx9pzhj 3097 3 treatment treatment NN cord-005646-xhx9pzhj 3097 4 varied vary VBN cord-005646-xhx9pzhj 3097 5 from from IN cord-005646-xhx9pzhj 3097 6 1 1 CD cord-005646-xhx9pzhj 3097 7 to to TO cord-005646-xhx9pzhj 3097 8 20 20 CD cord-005646-xhx9pzhj 3097 9 days day NNS cord-005646-xhx9pzhj 3097 10 . . . cord-005646-xhx9pzhj 3098 1 Combined combine VBN cord-005646-xhx9pzhj 3098 2 trealment trealment NN cord-005646-xhx9pzhj 3098 3 with with IN cord-005646-xhx9pzhj 3098 4 HFOV HFOV NNP cord-005646-xhx9pzhj 3098 5 and and CC cord-005646-xhx9pzhj 3098 6 inhaled inhale VBN cord-005646-xhx9pzhj 3098 7 NO no DT cord-005646-xhx9pzhj 3098 8 improved improve VBN cord-005646-xhx9pzhj 3098 9 oxygenation oxygenation NN cord-005646-xhx9pzhj 3098 10 and and CC cord-005646-xhx9pzhj 3098 11 carbon carbon NN cord-005646-xhx9pzhj 3098 12 dioxide dioxide NN cord-005646-xhx9pzhj 3098 13 elimination elimination NN cord-005646-xhx9pzhj 3098 14 in in IN cord-005646-xhx9pzhj 3098 15 12 12 CD cord-005646-xhx9pzhj 3098 16 out out IN cord-005646-xhx9pzhj 3098 17 of of IN cord-005646-xhx9pzhj 3098 18 13 13 CD cord-005646-xhx9pzhj 3098 19 treated treat VBN cord-005646-xhx9pzhj 3098 20 childretL childretL NNP cord-005646-xhx9pzhj 3098 21 5 5 CD cord-005646-xhx9pzhj 3098 22 patients patient NNS cord-005646-xhx9pzhj 3098 23 died die VBD cord-005646-xhx9pzhj 3098 24 , , , cord-005646-xhx9pzhj 3098 25 3 3 CD cord-005646-xhx9pzhj 3098 26 due due IN cord-005646-xhx9pzhj 3098 27 to to IN cord-005646-xhx9pzhj 3098 28 their -PRON- PRP$ cord-005646-xhx9pzhj 3098 29 underlying underlying JJ cord-005646-xhx9pzhj 3098 30 congenital congenital JJ cord-005646-xhx9pzhj 3098 31 heart heart NN cord-005646-xhx9pzhj 3098 32 disease disease NN cord-005646-xhx9pzhj 3098 33 , , , cord-005646-xhx9pzhj 3098 34 one one CD cord-005646-xhx9pzhj 3098 35 of of IN cord-005646-xhx9pzhj 3098 36 asphyxia asphyxia NN cord-005646-xhx9pzhj 3098 37 due due IN cord-005646-xhx9pzhj 3098 38 to to IN cord-005646-xhx9pzhj 3098 39 RSV rsv NN cord-005646-xhx9pzhj 3098 40 - - HYPH cord-005646-xhx9pzhj 3098 41 infection infection NN cord-005646-xhx9pzhj 3098 42 and and CC cord-005646-xhx9pzhj 3098 43 one one CD cord-005646-xhx9pzhj 3098 44 of of IN cord-005646-xhx9pzhj 3098 45 CDH CDH NNP cord-005646-xhx9pzhj 3098 46 with with IN cord-005646-xhx9pzhj 3098 47 progressive progressive JJ cord-005646-xhx9pzhj 3098 48 hypoxia hypoxia NN cord-005646-xhx9pzhj 3098 49 and and CC cord-005646-xhx9pzhj 3098 50 multiple multiple JJ cord-005646-xhx9pzhj 3098 51 organ organ NN cord-005646-xhx9pzhj 3098 52 failure failure NN cord-005646-xhx9pzhj 3098 53 . . . cord-005646-xhx9pzhj 3099 1 Combined combine VBN cord-005646-xhx9pzhj 3099 2 treatment treatment NN cord-005646-xhx9pzhj 3099 3 with with IN cord-005646-xhx9pzhj 3099 4 HFOV HFOV NNP cord-005646-xhx9pzhj 3099 5 and and CC cord-005646-xhx9pzhj 3099 6 inhaled inhale VBN cord-005646-xhx9pzhj 3099 7 NO no DT cord-005646-xhx9pzhj 3099 8 improves improve VBZ cord-005646-xhx9pzhj 3099 9 oxygenation oxygenation NN cord-005646-xhx9pzhj 3099 10 in in IN cord-005646-xhx9pzhj 3099 11 severely severely RB cord-005646-xhx9pzhj 3099 12 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3099 13 children child NNS cord-005646-xhx9pzhj 3099 14 . . . cord-005646-xhx9pzhj 3100 1 Treatment treatment NN cord-005646-xhx9pzhj 3100 2 should should MD cord-005646-xhx9pzhj 3100 3 be be VB cord-005646-xhx9pzhj 3100 4 slarted slarte VBN cord-005646-xhx9pzhj 3100 5 early early RB cord-005646-xhx9pzhj 3100 6 to to TO cord-005646-xhx9pzhj 3100 7 reduce reduce VB cord-005646-xhx9pzhj 3100 8 the the DT cord-005646-xhx9pzhj 3100 9 risk risk NN cord-005646-xhx9pzhj 3100 10 for for IN cord-005646-xhx9pzhj 3100 11 chronic chronic JJ cord-005646-xhx9pzhj 3100 12 lung lung NN cord-005646-xhx9pzhj 3100 13 injury injury NN cord-005646-xhx9pzhj 3100 14 following follow VBG cord-005646-xhx9pzhj 3100 15 barotranma barotranma NN cord-005646-xhx9pzhj 3100 16 and and CC cord-005646-xhx9pzhj 3100 17 high high JJ cord-005646-xhx9pzhj 3100 18 oxygen oxygen NN cord-005646-xhx9pzhj 3100 19 concentrations concentration NNS cord-005646-xhx9pzhj 3100 20 . . . cord-005646-xhx9pzhj 3101 1 We -PRON- PRP cord-005646-xhx9pzhj 3101 2 speculate speculate VBP cord-005646-xhx9pzhj 3101 3 that that IN cord-005646-xhx9pzhj 3101 4 the the DT cord-005646-xhx9pzhj 3101 5 combined combine VBN cord-005646-xhx9pzhj 3101 6 HFOV HFOV NNP cord-005646-xhx9pzhj 3101 7 - - HYPH cord-005646-xhx9pzhj 3101 8 NO NO NNP cord-005646-xhx9pzhj 3101 9 may may MD cord-005646-xhx9pzhj 3101 10 reduce reduce VB cord-005646-xhx9pzhj 3101 11 the the DT cord-005646-xhx9pzhj 3101 12 use use NN cord-005646-xhx9pzhj 3101 13 of of IN cord-005646-xhx9pzhj 3101 14 ECMO ECMO NNP cord-005646-xhx9pzhj 3101 15 , , , cord-005646-xhx9pzhj 3101 16 and and CC cord-005646-xhx9pzhj 3101 17 that that IN cord-005646-xhx9pzhj 3101 18 it -PRON- PRP cord-005646-xhx9pzhj 3101 19 may may MD cord-005646-xhx9pzhj 3101 20 improve improve VB cord-005646-xhx9pzhj 3101 21 outcome outcome NN cord-005646-xhx9pzhj 3101 22 in in IN cord-005646-xhx9pzhj 3101 23 ceotres ceotre NNS cord-005646-xhx9pzhj 3101 24 where where WRB cord-005646-xhx9pzhj 3101 25 ECMO ECMO NNP cord-005646-xhx9pzhj 3101 26 programmes programme NNS cord-005646-xhx9pzhj 3101 27 are be VBP cord-005646-xhx9pzhj 3101 28 not not RB cord-005646-xhx9pzhj 3101 29 introduced introduce VBN cord-005646-xhx9pzhj 3101 30 . . . cord-005646-xhx9pzhj 3102 1 Apart apart RB cord-005646-xhx9pzhj 3102 2 from from IN cord-005646-xhx9pzhj 3102 3 its -PRON- PRP$ cord-005646-xhx9pzhj 3102 4 vasodilative vasodilative JJ cord-005646-xhx9pzhj 3102 5 properties property NNS cord-005646-xhx9pzhj 3102 6 nitric nitric NN cord-005646-xhx9pzhj 3102 7 oxide oxide NN cord-005646-xhx9pzhj 3102 8 appears appear VBZ cord-005646-xhx9pzhj 3102 9 to to TO cord-005646-xhx9pzhj 3102 10 act act VB cord-005646-xhx9pzhj 3102 11 also also RB cord-005646-xhx9pzhj 3102 12 in in IN cord-005646-xhx9pzhj 3102 13 physiologic physiologic JJ cord-005646-xhx9pzhj 3102 14 immune immune JJ cord-005646-xhx9pzhj 3102 15 defense defense NN cord-005646-xhx9pzhj 3102 16 . . . cord-005646-xhx9pzhj 3103 1 Intracetlular intracetlular JJ cord-005646-xhx9pzhj 3103 2 concentrations concentration NNS cord-005646-xhx9pzhj 3103 3 of of IN cord-005646-xhx9pzhj 3103 4 NO no DT cord-005646-xhx9pzhj 3103 5 synthesized synthesize VBN cord-005646-xhx9pzhj 3103 6 by by IN cord-005646-xhx9pzhj 3103 7 macrophages macrophage NNS cord-005646-xhx9pzhj 3103 8 are be VBP cord-005646-xhx9pzhj 3103 9 in in IN cord-005646-xhx9pzhj 3103 10 the the DT cord-005646-xhx9pzhj 3103 11 range range NN cord-005646-xhx9pzhj 3103 12 of of IN cord-005646-xhx9pzhj 3103 13 103 103 CD cord-005646-xhx9pzhj 3103 14 above above IN cord-005646-xhx9pzhj 3103 15 those those DT cord-005646-xhx9pzhj 3103 16 produced produce VBN cord-005646-xhx9pzhj 3103 17 by by IN cord-005646-xhx9pzhj 3103 18 vascular vascular JJ cord-005646-xhx9pzhj 3103 19 endothelium endothelium NN cord-005646-xhx9pzhj 3103 20 . . . cord-005646-xhx9pzhj 3104 1 We -PRON- PRP cord-005646-xhx9pzhj 3104 2 investigated investigate VBD cord-005646-xhx9pzhj 3104 3 the the DT cord-005646-xhx9pzhj 3104 4 bacteriostatic bacteriostatic JJ cord-005646-xhx9pzhj 3104 5 effect effect NN cord-005646-xhx9pzhj 3104 6 of of IN cord-005646-xhx9pzhj 3104 7 nitric nitric JJ cord-005646-xhx9pzhj 3104 8 oxide oxide NN cord-005646-xhx9pzhj 3104 9 at at IN cord-005646-xhx9pzhj 3104 10 concentrations concentration NNS cord-005646-xhx9pzhj 3104 11 used use VBN cord-005646-xhx9pzhj 3104 12 during during IN cord-005646-xhx9pzhj 3104 13 inhaled inhale VBN cord-005646-xhx9pzhj 3104 14 therapy therapy NN cord-005646-xhx9pzhj 3104 15 for for IN cord-005646-xhx9pzhj 3104 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3104 17 vasodilation vasodilation NN cord-005646-xhx9pzhj 3104 18 in in IN cord-005646-xhx9pzhj 3104 19 neonates neonate NNS cord-005646-xhx9pzhj 3104 20 . . . cord-005646-xhx9pzhj 3105 1 Ten ten CD cord-005646-xhx9pzhj 3105 2 different different JJ cord-005646-xhx9pzhj 3105 3 strains strain NNS cord-005646-xhx9pzhj 3105 4 of of IN cord-005646-xhx9pzhj 3105 5 five five CD cord-005646-xhx9pzhj 3105 6 species specie NNS cord-005646-xhx9pzhj 3105 7 were be VBD cord-005646-xhx9pzhj 3105 8 used use VBN cord-005646-xhx9pzhj 3105 9 ( ( -LRB- cord-005646-xhx9pzhj 3105 10 Staph Staph NNP cord-005646-xhx9pzhj 3105 11 . . . cord-005646-xhx9pzhj 3106 1 anrens anrens NNP cord-005646-xhx9pzhj 3106 2 , , , cord-005646-xhx9pzhj 3106 3 Staph Staph NNP cord-005646-xhx9pzhj 3106 4 . . . cord-005646-xhx9pzhj 3107 1 epidermidis epidermidis NNP cord-005646-xhx9pzhj 3107 2 , , , cord-005646-xhx9pzhj 3107 3 Strop Strop NNP cord-005646-xhx9pzhj 3107 4 . . . cord-005646-xhx9pzhj 3108 1 group group NN cord-005646-xhx9pzhj 3108 2 B B NNP cord-005646-xhx9pzhj 3108 3 [ [ -LRB- cord-005646-xhx9pzhj 3108 4 GBS GBS NNP cord-005646-xhx9pzhj 3108 5 ] ] -RRB- cord-005646-xhx9pzhj 3108 6 , , , cord-005646-xhx9pzhj 3108 7 E. E. NNP cord-005646-xhx9pzhj 3108 8 coil coil NN cord-005646-xhx9pzhj 3108 9 and and CC cord-005646-xhx9pzhj 3108 10 Pseudomenas Pseudomenas NNP cord-005646-xhx9pzhj 3108 11 aeruginosa aeruginosa NN cord-005646-xhx9pzhj 3108 12 ) ) -RRB- cord-005646-xhx9pzhj 3108 13 , , , cord-005646-xhx9pzhj 3108 14 which which WDT cord-005646-xhx9pzhj 3108 15 are be VBP cord-005646-xhx9pzhj 3108 16 ~e ~e WRB cord-005646-xhx9pzhj 3108 17 most most RBS cord-005646-xhx9pzhj 3108 18 often often RB cord-005646-xhx9pzhj 3108 19 tracheally tracheally RB cord-005646-xhx9pzhj 3108 20 isolated isolate VBN cord-005646-xhx9pzhj 3108 21 bacteria bacteria NNS cord-005646-xhx9pzhj 3108 22 in in IN cord-005646-xhx9pzhj 3108 23 mechanically mechanically RB cord-005646-xhx9pzhj 3108 24 ventilated ventilate VBN cord-005646-xhx9pzhj 3108 25 premature premature JJ cord-005646-xhx9pzhj 3108 26 infants infant NNS cord-005646-xhx9pzhj 3108 27 and and CC cord-005646-xhx9pzhj 3108 28 neonates neonate NNS cord-005646-xhx9pzhj 3108 29 . . . cord-005646-xhx9pzhj 3109 1 We -PRON- PRP cord-005646-xhx9pzhj 3109 2 compared compare VBD cord-005646-xhx9pzhj 3109 3 bacterial bacterial JJ cord-005646-xhx9pzhj 3109 4 growth growth NN cord-005646-xhx9pzhj 3109 5 of of IN cord-005646-xhx9pzhj 3109 6 cultures culture NNS cord-005646-xhx9pzhj 3109 7 applying apply VBG cord-005646-xhx9pzhj 3109 8 three three CD cord-005646-xhx9pzhj 3109 9 different different JJ cord-005646-xhx9pzhj 3109 10 concentrations concentration NNS cord-005646-xhx9pzhj 3109 11 of of IN cord-005646-xhx9pzhj 3109 12 nitric nitric NN cord-005646-xhx9pzhj 3109 13 oxide oxide NN cord-005646-xhx9pzhj 3109 14 ( ( -LRB- cord-005646-xhx9pzhj 3109 15 40 40 CD cord-005646-xhx9pzhj 3109 16 ppm ppm NN cord-005646-xhx9pzhj 3109 17 . . . cord-005646-xhx9pzhj 3110 1 80 80 CD cord-005646-xhx9pzhj 3110 2 ppm ppm NN cord-005646-xhx9pzhj 3110 3 , , , cord-005646-xhx9pzhj 3110 4 120 120 CD cord-005646-xhx9pzhj 3110 5 ppm ppm NN cord-005646-xhx9pzhj 3110 6 ) ) -RRB- cord-005646-xhx9pzhj 3110 7 m m NFP cord-005646-xhx9pzhj 3110 8 the the DT cord-005646-xhx9pzhj 3110 9 growth growth NN cord-005646-xhx9pzhj 3110 10 of of IN cord-005646-xhx9pzhj 3110 11 the the DT cord-005646-xhx9pzhj 3110 12 same same JJ cord-005646-xhx9pzhj 3110 13 strains strain NNS cord-005646-xhx9pzhj 3110 14 in in IN cord-005646-xhx9pzhj 3110 15 room room NN cord-005646-xhx9pzhj 3110 16 air air NN cord-005646-xhx9pzhj 3110 17 for for IN cord-005646-xhx9pzhj 3110 18 a a DT cord-005646-xhx9pzhj 3110 19 duration duration NN cord-005646-xhx9pzhj 3110 20 of of IN cord-005646-xhx9pzhj 3110 21 24 24 CD cord-005646-xhx9pzhj 3110 22 hours hour NNS cord-005646-xhx9pzhj 3110 23 . . . cord-005646-xhx9pzhj 3111 1 No no DT cord-005646-xhx9pzhj 3111 2 bacteriostatic bacteriostatic JJ cord-005646-xhx9pzhj 3111 3 effect effect NN cord-005646-xhx9pzhj 3111 4 was be VBD cord-005646-xhx9pzhj 3111 5 demonstrable demonstrable JJ cord-005646-xhx9pzhj 3111 6 at at IN cord-005646-xhx9pzhj 3111 7 NO no DT cord-005646-xhx9pzhj 3111 8 concentratioes concentratioe NNS cord-005646-xhx9pzhj 3111 9 of of IN cord-005646-xhx9pzhj 3111 10 40 40 CD cord-005646-xhx9pzhj 3111 11 ppm ppm NN cord-005646-xhx9pzhj 3111 12 . . . cord-005646-xhx9pzhj 3112 1 E. E. NNP cord-005646-xhx9pzhj 3112 2 coil coil NN cord-005646-xhx9pzhj 3112 3 showed show VBD cord-005646-xhx9pzhj 3112 4 decreased decrease VBN cord-005646-xhx9pzhj 3112 5 bacterial bacterial JJ cord-005646-xhx9pzhj 3112 6 growth growth NN cord-005646-xhx9pzhj 3112 7 at at IN cord-005646-xhx9pzhj 3112 8 80 80 CD cord-005646-xhx9pzhj 3112 9 ppm ppm NN cord-005646-xhx9pzhj 3112 10 and and CC cord-005646-xhx9pzhj 3112 11 120 120 CD cord-005646-xhx9pzhj 3112 12 ppm ppm NN cord-005646-xhx9pzhj 3112 13 , , , cord-005646-xhx9pzhj 3112 14 however however RB cord-005646-xhx9pzhj 3112 15 without without IN cord-005646-xhx9pzhj 3112 16 reaching reach VBG cord-005646-xhx9pzhj 3112 17 statistical statistical JJ cord-005646-xhx9pzhj 3112 18 significance significance NN cord-005646-xhx9pzhj 3112 19 ( ( -LRB- cord-005646-xhx9pzhj 3112 20 p=0.058 p=0.058 NNP cord-005646-xhx9pzhj 3112 21 ) ) -RRB- cord-005646-xhx9pzhj 3112 22 . . . cord-005646-xhx9pzhj 3113 1 At at IN cord-005646-xhx9pzhj 3113 2 nitric nitric NN cord-005646-xhx9pzhj 3113 3 oxide oxide NN cord-005646-xhx9pzhj 3113 4 concentrations concentration NNS cord-005646-xhx9pzhj 3113 5 of of IN cord-005646-xhx9pzhj 3113 6 i20 i20 NNP cord-005646-xhx9pzhj 3113 7 ppm ppm NN cord-005646-xhx9pzhj 3113 8 Staph staph NN cord-005646-xhx9pzhj 3113 9 . . . cord-005646-xhx9pzhj 3114 1 epidermidis epidermidis NNP cord-005646-xhx9pzhj 3114 2 and and CC cord-005646-xhx9pzhj 3114 3 GBS GBS NNP cord-005646-xhx9pzhj 3114 4 grew grow VBD cord-005646-xhx9pzhj 3114 5 significantly significantly RB cord-005646-xhx9pzhj 3114 6 less less RBR cord-005646-xhx9pzhj 3114 7 as as IN cord-005646-xhx9pzhj 3114 8 compared compare VBN cord-005646-xhx9pzhj 3114 9 to to IN cord-005646-xhx9pzhj 3114 10 colonies colony NNS cord-005646-xhx9pzhj 3114 11 of of IN cord-005646-xhx9pzhj 3114 12 the the DT cord-005646-xhx9pzhj 3114 13 same same JJ cord-005646-xhx9pzhj 3114 14 strains strain NNS cord-005646-xhx9pzhj 3114 15 in in IN cord-005646-xhx9pzhj 3114 16 room room NN cord-005646-xhx9pzhj 3114 17 air air NN cord-005646-xhx9pzhj 3114 18 . . . cord-005646-xhx9pzhj 3115 1 No no DT cord-005646-xhx9pzhj 3115 2 effects effect NNS cord-005646-xhx9pzhj 3115 3 were be VBD cord-005646-xhx9pzhj 3115 4 found find VBN cord-005646-xhx9pzhj 3115 5 regarding regard VBG cord-005646-xhx9pzhj 3115 6 the the DT cord-005646-xhx9pzhj 3115 7 growth growth NN cord-005646-xhx9pzhj 3115 8 of of IN cord-005646-xhx9pzhj 3115 9 Staph Staph NNP cord-005646-xhx9pzhj 3115 10 . . . cord-005646-xhx9pzhj 3116 1 aureus aureus NN cord-005646-xhx9pzhj 3116 2 and and CC cord-005646-xhx9pzhj 3116 3 Pseudomonas Pseudomonas NNP cord-005646-xhx9pzhj 3116 4 aneruginosa aneruginosa RB cord-005646-xhx9pzhj 3116 5 . . . cord-005646-xhx9pzhj 3117 1 We -PRON- PRP cord-005646-xhx9pzhj 3117 2 conclude conclude VBP cord-005646-xhx9pzhj 3117 3 that that IN cord-005646-xhx9pzhj 3117 4 nitric nitric NN cord-005646-xhx9pzhj 3117 5 oxide oxide NN cord-005646-xhx9pzhj 3117 6 has have VBZ cord-005646-xhx9pzhj 3117 7 a a DT cord-005646-xhx9pzhj 3117 8 selective selective JJ cord-005646-xhx9pzhj 3117 9 bacteriostatic bacteriostatic JJ cord-005646-xhx9pzhj 3117 10 effect effect NN cord-005646-xhx9pzhj 3117 11 on on IN cord-005646-xhx9pzhj 3117 12 some some DT cord-005646-xhx9pzhj 3117 13 of of IN cord-005646-xhx9pzhj 3117 14 the the DT cord-005646-xhx9pzhj 3117 15 most most RBS cord-005646-xhx9pzhj 3117 16 often often RB cord-005646-xhx9pzhj 3117 17 trachealb trachealb JJ cord-005646-xhx9pzhj 3117 18 , , , cord-005646-xhx9pzhj 3117 19 isolated isolate VBN cord-005646-xhx9pzhj 3117 20 bacteria bacteria NNS cord-005646-xhx9pzhj 3117 21 in in IN cord-005646-xhx9pzhj 3117 22 premature premature JJ cord-005646-xhx9pzhj 3117 23 infants infant NNS cord-005646-xhx9pzhj 3117 24 and and CC cord-005646-xhx9pzhj 3117 25 neonates neonate NNS cord-005646-xhx9pzhj 3117 26 . . . cord-005646-xhx9pzhj 3118 1 This this DT cord-005646-xhx9pzhj 3118 2 effect effect NN cord-005646-xhx9pzhj 3118 3 appears appear VBZ cord-005646-xhx9pzhj 3118 4 to to TO cord-005646-xhx9pzhj 3118 5 be be VB cord-005646-xhx9pzhj 3118 6 dose dose NN cord-005646-xhx9pzhj 3118 7 - - HYPH cord-005646-xhx9pzhj 3118 8 dependant dependant JJ cord-005646-xhx9pzhj 3118 9 and and CC cord-005646-xhx9pzhj 3118 10 occurs occur VBZ cord-005646-xhx9pzhj 3118 11 in in IN cord-005646-xhx9pzhj 3118 12 the the DT cord-005646-xhx9pzhj 3118 13 upper upper JJ cord-005646-xhx9pzhj 3118 14 range range NN cord-005646-xhx9pzhj 3118 15 of of IN cord-005646-xhx9pzhj 3118 16 dosages dosage NNS cord-005646-xhx9pzhj 3118 17 used use VBN cord-005646-xhx9pzhj 3118 18 with with IN cord-005646-xhx9pzhj 3118 19 inhaled inhale VBN cord-005646-xhx9pzhj 3118 20 NO no DT cord-005646-xhx9pzhj 3118 21 therapy therapy NN cord-005646-xhx9pzhj 3118 22 . . . cord-005646-xhx9pzhj 3119 1 Further further JJ cord-005646-xhx9pzhj 3119 2 research research NN cord-005646-xhx9pzhj 3119 3 is be VBZ cord-005646-xhx9pzhj 3119 4 required require VBN cord-005646-xhx9pzhj 3119 5 in in IN cord-005646-xhx9pzhj 3119 6 order order NN cord-005646-xhx9pzhj 3119 7 to to TO cord-005646-xhx9pzhj 3119 8 examine examine VB cord-005646-xhx9pzhj 3119 9 the the DT cord-005646-xhx9pzhj 3119 10 mechanisms mechanism NNS cord-005646-xhx9pzhj 3119 11 of of IN cord-005646-xhx9pzhj 3119 12 action action NN cord-005646-xhx9pzhj 3119 13 as as RB cord-005646-xhx9pzhj 3119 14 well well RB cord-005646-xhx9pzhj 3119 15 as as IN cord-005646-xhx9pzhj 3119 16 specific specific JJ cord-005646-xhx9pzhj 3119 17 interactions interaction NNS cord-005646-xhx9pzhj 3119 18 between between IN cord-005646-xhx9pzhj 3119 19 different different JJ cord-005646-xhx9pzhj 3119 20 strains strain NNS cord-005646-xhx9pzhj 3119 21 of of IN cord-005646-xhx9pzhj 3119 22 bacteria bacteria NNS cord-005646-xhx9pzhj 3119 23 and and CC cord-005646-xhx9pzhj 3119 24 nitric nitric NN cord-005646-xhx9pzhj 3119 25 oxide oxide NN cord-005646-xhx9pzhj 3119 26 . . . cord-005646-xhx9pzhj 3120 1 The the DT cord-005646-xhx9pzhj 3120 2 No no NN cord-005646-xhx9pzhj 3120 3 , , , cord-005646-xhx9pzhj 3120 4 Box Box NNP cord-005646-xhx9pzhj 3120 5 monitor monitor NN cord-005646-xhx9pzhj 3120 6 ( ( -LRB- cord-005646-xhx9pzhj 3120 7 Bedfont Bedfont NNP cord-005646-xhx9pzhj 3120 8 , , , cord-005646-xhx9pzhj 3120 9 Kent Kent NNP cord-005646-xhx9pzhj 3120 10 , , , cord-005646-xhx9pzhj 3120 11 UK UK NNP cord-005646-xhx9pzhj 3120 12 ) ) -RRB- cord-005646-xhx9pzhj 3120 13 is be VBZ cord-005646-xhx9pzhj 3120 14 used use VBN cord-005646-xhx9pzhj 3120 15 to to TO cord-005646-xhx9pzhj 3120 16 monitor monitor VB cord-005646-xhx9pzhj 3120 17 nitric nitric NN cord-005646-xhx9pzhj 3120 18 oxide oxide NN cord-005646-xhx9pzhj 3120 19 ( ( -LRB- cord-005646-xhx9pzhj 3120 20 NO no UH cord-005646-xhx9pzhj 3120 21 ) ) -RRB- cord-005646-xhx9pzhj 3120 22 and and CC cord-005646-xhx9pzhj 3120 23 nitdc nitdc NN cord-005646-xhx9pzhj 3120 24 dioxide dioxide NN cord-005646-xhx9pzhj 3120 25 ( ( -LRB- cord-005646-xhx9pzhj 3120 26 NO no DT cord-005646-xhx9pzhj 3120 27 2 2 CD cord-005646-xhx9pzhj 3120 28 ) ) -RRB- cord-005646-xhx9pzhj 3120 29 during during IN cord-005646-xhx9pzhj 3120 30 NO no DT cord-005646-xhx9pzhj 3120 31 administration administration NN cord-005646-xhx9pzhj 3120 32 in in IN cord-005646-xhx9pzhj 3120 33 ventilated ventilate VBN cord-005646-xhx9pzhj 3120 34 neonates neonate NNS cord-005646-xhx9pzhj 3120 35 . . . cord-005646-xhx9pzhj 3121 1 According accord VBG cord-005646-xhx9pzhj 3121 2 to to IN cord-005646-xhx9pzhj 3121 3 the the DT cord-005646-xhx9pzhj 3121 4 manufacturers manufacturer NNS cord-005646-xhx9pzhj 3121 5 specifications specification VBZ cord-005646-xhx9pzhj 3121 6 the the DT cord-005646-xhx9pzhj 3121 7 monitor monitor NN cord-005646-xhx9pzhj 3121 8 can can MD cord-005646-xhx9pzhj 3121 9 be be VB cord-005646-xhx9pzhj 3121 10 applied apply VBN cord-005646-xhx9pzhj 3121 11 in in IN cord-005646-xhx9pzhj 3121 12 cases case NNS cord-005646-xhx9pzhj 3121 13 where where WRB cord-005646-xhx9pzhj 3121 14 airway airway NN cord-005646-xhx9pzhj 3121 15 pressures pressure NNS cord-005646-xhx9pzhj 3121 16 range range VBP cord-005646-xhx9pzhj 3121 17 from from IN cord-005646-xhx9pzhj 3121 18 5 5 CD cord-005646-xhx9pzhj 3121 19 to to TO cord-005646-xhx9pzhj 3121 20 50 50 CD cord-005646-xhx9pzhj 3121 21 mbar mbar NNS cord-005646-xhx9pzhj 3121 22 . . . cord-005646-xhx9pzhj 3122 1 We -PRON- PRP cord-005646-xhx9pzhj 3122 2 investigated investigate VBD cord-005646-xhx9pzhj 3122 3 in in IN cord-005646-xhx9pzhj 3122 4 - - HYPH cord-005646-xhx9pzhj 3122 5 vitro vitro FW cord-005646-xhx9pzhj 3122 6 the the DT cord-005646-xhx9pzhj 3122 7 accuracy accuracy NN cord-005646-xhx9pzhj 3122 8 of of IN cord-005646-xhx9pzhj 3122 9 the the DT cord-005646-xhx9pzhj 3122 10 NO no JJ cord-005646-xhx9pzhj 3122 11 monitor monitor NN cord-005646-xhx9pzhj 3122 12 in in IN cord-005646-xhx9pzhj 3122 13 a a DT cord-005646-xhx9pzhj 3122 14 range range NN cord-005646-xhx9pzhj 3122 15 of of IN cord-005646-xhx9pzhj 3122 16 ventilatory ventilatory JJ cord-005646-xhx9pzhj 3122 17 conditions condition NNS cord-005646-xhx9pzhj 3122 18 . . . cord-005646-xhx9pzhj 3123 1 Using use VBG cord-005646-xhx9pzhj 3123 2 a a DT cord-005646-xhx9pzhj 3123 3 Dr Dr NNP cord-005646-xhx9pzhj 3123 4 ~ ~ NNP cord-005646-xhx9pzhj 3123 5 ger ger NNP cord-005646-xhx9pzhj 3123 6 Babylog Babylog NNP cord-005646-xhx9pzhj 3123 7 8000 8000 CD cord-005646-xhx9pzhj 3123 8 we -PRON- PRP cord-005646-xhx9pzhj 3123 9 ventilated ventilate VBD cord-005646-xhx9pzhj 3123 10 an an DT cord-005646-xhx9pzhj 3123 11 artificial artificial JJ cord-005646-xhx9pzhj 3123 12 lung lung NN cord-005646-xhx9pzhj 3123 13 . . . cord-005646-xhx9pzhj 3124 1 NO no UH cord-005646-xhx9pzhj 3124 2 was be VBD cord-005646-xhx9pzhj 3124 3 administered administer VBN cord-005646-xhx9pzhj 3124 4 { { -LRB- cord-005646-xhx9pzhj 3124 5 800 800 CD cord-005646-xhx9pzhj 3124 6 ppm ppm NN cord-005646-xhx9pzhj 3125 1 NO no RB cord-005646-xhx9pzhj 3125 2 in in IN cord-005646-xhx9pzhj 3125 3 100 100 CD cord-005646-xhx9pzhj 3125 4 % % NN cord-005646-xhx9pzhj 3125 5 nitrogen nitrogen NN cord-005646-xhx9pzhj 3125 6 ) ) -RRB- cord-005646-xhx9pzhj 3125 7 with with IN cord-005646-xhx9pzhj 3125 8 a a DT cord-005646-xhx9pzhj 3125 9 mass mass JJ cord-005646-xhx9pzhj 3125 10 flow flow NN cord-005646-xhx9pzhj 3125 11 controller controller NN cord-005646-xhx9pzhj 3125 12 to to IN cord-005646-xhx9pzhj 3125 13 the the DT cord-005646-xhx9pzhj 3125 14 inspiratory inspiratory JJ cord-005646-xhx9pzhj 3125 15 tube tube NN cord-005646-xhx9pzhj 3125 16 , , , cord-005646-xhx9pzhj 3125 17 at at IN cord-005646-xhx9pzhj 3125 18 a a DT cord-005646-xhx9pzhj 3125 19 distance distance NN cord-005646-xhx9pzhj 3125 20 of of IN cord-005646-xhx9pzhj 3125 21 20 20 CD cord-005646-xhx9pzhj 3125 22 cm cm NNS cord-005646-xhx9pzhj 3125 23 from from IN cord-005646-xhx9pzhj 3125 24 the the DT cord-005646-xhx9pzhj 3125 25 Y Y NNP cord-005646-xhx9pzhj 3125 26 - - HYPH cord-005646-xhx9pzhj 3125 27 piece piece NN cord-005646-xhx9pzhj 3125 28 . . . cord-005646-xhx9pzhj 3126 1 The the DT cord-005646-xhx9pzhj 3126 2 NO no DT cord-005646-xhx9pzhj 3126 3 target target NN cord-005646-xhx9pzhj 3126 4 value value NN cord-005646-xhx9pzhj 3126 5 was be VBD cord-005646-xhx9pzhj 3126 6 set set VBN cord-005646-xhx9pzhj 3126 7 to to IN cord-005646-xhx9pzhj 3126 8 10 10 CD cord-005646-xhx9pzhj 3126 9 ppm ppm NN cord-005646-xhx9pzhj 3126 10 . . . cord-005646-xhx9pzhj 3127 1 The the DT cord-005646-xhx9pzhj 3127 2 ventilator ventilator NN cord-005646-xhx9pzhj 3127 3 was be VBD cord-005646-xhx9pzhj 3127 4 operated operate VBN cord-005646-xhx9pzhj 3127 5 in in IN cord-005646-xhx9pzhj 3127 6 both both CC cord-005646-xhx9pzhj 3127 7 CPAP CPAP NNP cord-005646-xhx9pzhj 3127 8 and and CC cord-005646-xhx9pzhj 3127 9 IPPV IPPV NNP cord-005646-xhx9pzhj 3127 10 modes mode NNS cord-005646-xhx9pzhj 3127 11 at at IN cord-005646-xhx9pzhj 3127 12 different different JJ cord-005646-xhx9pzhj 3127 13 settings setting NNS cord-005646-xhx9pzhj 3127 14 . . . cord-005646-xhx9pzhj 3128 1 The the DT cord-005646-xhx9pzhj 3128 2 NO no DT cord-005646-xhx9pzhj 3128 3 sampling sampling NN cord-005646-xhx9pzhj 3128 4 tube tube NN cord-005646-xhx9pzhj 3128 5 was be VBD cord-005646-xhx9pzhj 3128 6 placed place VBN cord-005646-xhx9pzhj 3128 7 on on IN cord-005646-xhx9pzhj 3128 8 two two CD cord-005646-xhx9pzhj 3128 9 different different JJ cord-005646-xhx9pzhj 3128 10 locations location NNS cord-005646-xhx9pzhj 3128 11 ; ; : cord-005646-xhx9pzhj 3128 12 in in IN cord-005646-xhx9pzhj 3128 13 the the DT cord-005646-xhx9pzhj 3128 14 inspiratory inspiratory JJ cord-005646-xhx9pzhj 3128 15 tube tube NN cord-005646-xhx9pzhj 3128 16 dose dose NN cord-005646-xhx9pzhj 3128 17 to to IN cord-005646-xhx9pzhj 3128 18 the the DT cord-005646-xhx9pzhj 3128 19 Y Y NNP cord-005646-xhx9pzhj 3128 20 - - HYPH cord-005646-xhx9pzhj 3128 21 piece piece NN cord-005646-xhx9pzhj 3128 22 ; ; : cord-005646-xhx9pzhj 3128 23 in in IN cord-005646-xhx9pzhj 3128 24 the the DT cord-005646-xhx9pzhj 3128 25 expiratory expiratory JJ cord-005646-xhx9pzhj 3128 26 tube tube NN cord-005646-xhx9pzhj 3128 27 haft haft NN cord-005646-xhx9pzhj 3128 28 way way NN cord-005646-xhx9pzhj 3128 29 between between IN cord-005646-xhx9pzhj 3128 30 the the DT cord-005646-xhx9pzhj 3128 31 Y Y NNP cord-005646-xhx9pzhj 3128 32 - - HYPH cord-005646-xhx9pzhj 3128 33 piece piece NN cord-005646-xhx9pzhj 3128 34 and and CC cord-005646-xhx9pzhj 3128 35 the the DT cord-005646-xhx9pzhj 3128 36 ventilator ventilator NN cord-005646-xhx9pzhj 3128 37 . . . cord-005646-xhx9pzhj 3129 1 The the DT cord-005646-xhx9pzhj 3129 2 NO no JJ cord-005646-xhx9pzhj 3129 3 - - HYPH cord-005646-xhx9pzhj 3129 4 monitor monitor NN cord-005646-xhx9pzhj 3129 5 was be VBD cord-005646-xhx9pzhj 3129 6 ca)ibrated ca)ibrate VBN cord-005646-xhx9pzhj 3129 7 with with IN cord-005646-xhx9pzhj 3129 8 84 84 CD cord-005646-xhx9pzhj 3129 9 ppm ppm NN cord-005646-xhx9pzhj 3129 10 NO no NN cord-005646-xhx9pzhj 3129 11 at at IN cord-005646-xhx9pzhj 3129 12 30 30 CD cord-005646-xhx9pzhj 3129 13 mbar mbar NN cord-005646-xhx9pzhj 3129 14 . . . cord-005646-xhx9pzhj 3130 1 Fig Fig NNP cord-005646-xhx9pzhj 3130 2 . . . cord-005646-xhx9pzhj 3131 1 1 1 CD cord-005646-xhx9pzhj 3131 2 and and CC cord-005646-xhx9pzhj 3131 3 2 2 CD cord-005646-xhx9pzhj 3131 4 show show VBP cord-005646-xhx9pzhj 3131 5 the the DT cord-005646-xhx9pzhj 3131 6 sensitivity sensitivity NN cord-005646-xhx9pzhj 3131 7 of of IN cord-005646-xhx9pzhj 3131 8 the the DT cord-005646-xhx9pzhj 3131 9 NO no JJ cord-005646-xhx9pzhj 3131 10 - - HYPH cord-005646-xhx9pzhj 3131 11 monitor monitor NN cord-005646-xhx9pzhj 3131 12 for for IN cord-005646-xhx9pzhj 3131 13 respectively respectively RB cord-005646-xhx9pzhj 3131 14 static static JJ cord-005646-xhx9pzhj 3131 15 pressure pressure NN cord-005646-xhx9pzhj 3131 16 ( ( -LRB- cord-005646-xhx9pzhj 3131 17 CPAP CPAP NNP cord-005646-xhx9pzhj 3131 18 ) ) -RRB- cord-005646-xhx9pzhj 3131 19 and and CC cord-005646-xhx9pzhj 3131 20 pulsatile pulsatile JJ cord-005646-xhx9pzhj 3131 21 pressure pressure NN cord-005646-xhx9pzhj 3131 22 ( ( -LRB- cord-005646-xhx9pzhj 3131 23 IPPV IPPV NNP cord-005646-xhx9pzhj 3131 24 ) ) -RRB- cord-005646-xhx9pzhj 3131 25 with with IN cord-005646-xhx9pzhj 3131 26 the the DT cord-005646-xhx9pzhj 3131 27 sampling sampling NN cord-005646-xhx9pzhj 3131 28 tube tube NN cord-005646-xhx9pzhj 3131 29 located locate VBN cord-005646-xhx9pzhj 3131 30 in in IN cord-005646-xhx9pzhj 3131 31 the the DT cord-005646-xhx9pzhj 3131 32 inspiratory inspiratory JJ cord-005646-xhx9pzhj 3131 33 tube tube NN cord-005646-xhx9pzhj 3131 34 . . . cord-005646-xhx9pzhj 3132 1 Fig Fig NNP cord-005646-xhx9pzhj 3132 2 . . . cord-005646-xhx9pzhj 3133 1 3 3 CD cord-005646-xhx9pzhj 3133 2 shows show VBZ cord-005646-xhx9pzhj 3133 3 the the DT cord-005646-xhx9pzhj 3133 4 resuR resuR NNP cord-005646-xhx9pzhj 3133 5 for for IN cord-005646-xhx9pzhj 3133 6 pulsatile pulsatile JJ cord-005646-xhx9pzhj 3133 7 pressure pressure NN cord-005646-xhx9pzhj 3133 8 with with IN cord-005646-xhx9pzhj 3133 9 sampling sampling NN cord-005646-xhx9pzhj 3133 10 in in IN cord-005646-xhx9pzhj 3133 11 the the DT cord-005646-xhx9pzhj 3133 12 expiratory expiratory JJ cord-005646-xhx9pzhj 3133 13 tube tube NN cord-005646-xhx9pzhj 3133 14 . . . cord-005646-xhx9pzhj 3134 1 We -PRON- PRP cord-005646-xhx9pzhj 3134 2 conclude conclude VBP cord-005646-xhx9pzhj 3134 3 that that IN cord-005646-xhx9pzhj 3134 4 the the DT cord-005646-xhx9pzhj 3134 5 accuracy accuracy NN cord-005646-xhx9pzhj 3134 6 of of IN cord-005646-xhx9pzhj 3134 7 the the DT cord-005646-xhx9pzhj 3134 8 Bedfont Bedfont NNP cord-005646-xhx9pzhj 3134 9 NO NO NNP cord-005646-xhx9pzhj 3134 10 - - HYPH cord-005646-xhx9pzhj 3134 11 monitor monitor NN cord-005646-xhx9pzhj 3134 12 is be VBZ cord-005646-xhx9pzhj 3134 13 dependent dependent JJ cord-005646-xhx9pzhj 3134 14 upon upon IN cord-005646-xhx9pzhj 3134 15 airway airway NN cord-005646-xhx9pzhj 3134 16 pressure pressure NN cord-005646-xhx9pzhj 3134 17 and and CC cord-005646-xhx9pzhj 3134 18 sampling sampling NN cord-005646-xhx9pzhj 3134 19 site site NN cord-005646-xhx9pzhj 3134 20 , , , cord-005646-xhx9pzhj 3134 21 the the DT cord-005646-xhx9pzhj 3134 22 latter latter JJ cord-005646-xhx9pzhj 3134 23 possibly possibly RB cord-005646-xhx9pzhj 3134 24 caused cause VBN cord-005646-xhx9pzhj 3134 25 by by IN cord-005646-xhx9pzhj 3134 26 incomplete incomplete JJ cord-005646-xhx9pzhj 3134 27 mixing mixing NN cord-005646-xhx9pzhj 3134 28 , , , cord-005646-xhx9pzhj 3134 29 Pressure pressure NN cord-005646-xhx9pzhj 3134 30 and and CC cord-005646-xhx9pzhj 3134 31 NO no UH cord-005646-xhx9pzhj 3134 32 are be VBP cord-005646-xhx9pzhj 3134 33 linearly linearly RB cord-005646-xhx9pzhj 3134 34 related relate VBN cord-005646-xhx9pzhj 3134 35 when when WRB cord-005646-xhx9pzhj 3134 36 sampling sampling NN cord-005646-xhx9pzhj 3134 37 occured occur VBD cord-005646-xhx9pzhj 3134 38 further far RBR cord-005646-xhx9pzhj 3134 39 away away RB cord-005646-xhx9pzhj 3134 40 from from IN cord-005646-xhx9pzhj 3134 41 the the DT cord-005646-xhx9pzhj 3134 42 administration administration NN cord-005646-xhx9pzhj 3134 43 site site NN cord-005646-xhx9pzhj 3134 44 . . . cord-005646-xhx9pzhj 3135 1 Based base VBN cord-005646-xhx9pzhj 3135 2 on on IN cord-005646-xhx9pzhj 3135 3 this this DT cord-005646-xhx9pzhj 3135 4 study study NN cord-005646-xhx9pzhj 3135 5 we -PRON- PRP cord-005646-xhx9pzhj 3135 6 suggest suggest VBP cord-005646-xhx9pzhj 3135 7 to to TO cord-005646-xhx9pzhj 3135 8 place place VB cord-005646-xhx9pzhj 3135 9 the the DT cord-005646-xhx9pzhj 3135 10 sampling sampling NN cord-005646-xhx9pzhj 3135 11 tube tube NN cord-005646-xhx9pzhj 3135 12 in in IN cord-005646-xhx9pzhj 3135 13 the the DT cord-005646-xhx9pzhj 3135 14 expiratory expiratory JJ cord-005646-xhx9pzhj 3135 15 tube tube NN cord-005646-xhx9pzhj 3135 16 . . . cord-005646-xhx9pzhj 3136 1 During during IN cord-005646-xhx9pzhj 3136 2 neonatal neonatal JJ cord-005646-xhx9pzhj 3136 3 care care NN cord-005646-xhx9pzhj 3136 4 the the DT cord-005646-xhx9pzhj 3136 5 clinician clinician NN cord-005646-xhx9pzhj 3136 6 should should MD cord-005646-xhx9pzhj 3136 7 be be VB cord-005646-xhx9pzhj 3136 8 aware aware JJ cord-005646-xhx9pzhj 3136 9 of of IN cord-005646-xhx9pzhj 3136 10 varying vary VBG cord-005646-xhx9pzhj 3136 11 inaccuracies inaccuracy NNS cord-005646-xhx9pzhj 3136 12 depending depend VBG cord-005646-xhx9pzhj 3136 13 on on IN cord-005646-xhx9pzhj 3136 14 the the DT cord-005646-xhx9pzhj 3136 15 respiratory respiratory JJ cord-005646-xhx9pzhj 3136 16 pressures pressure NNS cord-005646-xhx9pzhj 3136 17 . . . cord-005646-xhx9pzhj 3137 1 Hypothesis hypothesis NN cord-005646-xhx9pzhj 3137 2 : : : cord-005646-xhx9pzhj 3138 1 Availability availability NN cord-005646-xhx9pzhj 3138 2 of of IN cord-005646-xhx9pzhj 3138 3 therapy therapy NN cord-005646-xhx9pzhj 3138 4 with with IN cord-005646-xhx9pzhj 3138 5 inhaled inhale VBN cord-005646-xhx9pzhj 3138 6 nitric nitric NN cord-005646-xhx9pzhj 3138 7 oxide oxide NN cord-005646-xhx9pzhj 3138 8 ( ( -LRB- cord-005646-xhx9pzhj 3138 9 iNO iNO NNS cord-005646-xhx9pzhj 3138 10 ) ) -RRB- cord-005646-xhx9pzhj 3138 11 decreases decrease VBZ cord-005646-xhx9pzhj 3138 12 ECMO ecmo NN cord-005646-xhx9pzhj 3138 13 use use NN cord-005646-xhx9pzhj 3138 14 in in IN cord-005646-xhx9pzhj 3138 15 patients patient NNS cord-005646-xhx9pzhj 3138 16 referred refer VBN cord-005646-xhx9pzhj 3138 17 .to .to . cord-005646-xhx9pzhj 3139 1 a a DT cord-005646-xhx9pzhj 3139 2 tertiary tertiary JJ cord-005646-xhx9pzhj 3139 3 care care NN cord-005646-xhx9pzhj 3139 4 hospital hospital NN cord-005646-xhx9pzhj 3139 5 for for IN cord-005646-xhx9pzhj 3139 6 treatment treatment NN cord-005646-xhx9pzhj 3139 7 of of IN cord-005646-xhx9pzhj 3139 8 respiratory respiratory NN cord-005646-xhx9pzhj 3139 9 , , , cord-005646-xhx9pzhj 3139 10 failure failure NN cord-005646-xhx9pzhj 3139 11 unresponsive unresponsive JJ cord-005646-xhx9pzhj 3139 12 to to IN cord-005646-xhx9pzhj 3139 13 conventional conventional JJ cord-005646-xhx9pzhj 3139 14 therapies therapy NNS cord-005646-xhx9pzhj 3139 15 . . . cord-005646-xhx9pzhj 3140 1 Background background NN cord-005646-xhx9pzhj 3140 2 : : : cord-005646-xhx9pzhj 3141 1 At at IN cord-005646-xhx9pzhj 3141 2 Children Children NNP cord-005646-xhx9pzhj 3141 3 's 's POS cord-005646-xhx9pzhj 3141 4 Hospital Hospital NNP cord-005646-xhx9pzhj 3141 5 of of IN cord-005646-xhx9pzhj 3141 6 Wisconsin Wisconsin NNP cord-005646-xhx9pzhj 3141 7 ( ( -LRB- cord-005646-xhx9pzhj 3141 8 CHW CHW NNP cord-005646-xhx9pzhj 3141 9 ) ) -RRB- cord-005646-xhx9pzhj 3141 10 treatment treatment NN cord-005646-xhx9pzhj 3141 11 for for IN cord-005646-xhx9pzhj 3141 12 patients patient NNS cord-005646-xhx9pzhj 3141 13 who who WP cord-005646-xhx9pzhj 3141 14 have have VBP cord-005646-xhx9pzhj 3141 15 failed fail VBN cord-005646-xhx9pzhj 3141 16 conventional conventional JJ cord-005646-xhx9pzhj 3141 17 treatment treatment NN cord-005646-xhx9pzhj 3141 18 for for IN cord-005646-xhx9pzhj 3141 19 respiratory respiratory JJ cord-005646-xhx9pzhj 3141 20 failure failure NN cord-005646-xhx9pzhj 3141 21 , , , cord-005646-xhx9pzhj 3141 22 sometimes sometimes RB cord-005646-xhx9pzhj 3141 23 called call VBN cord-005646-xhx9pzhj 3141 24 " " `` cord-005646-xhx9pzhj 3141 25 rescue rescue NN cord-005646-xhx9pzhj 3141 26 " " '' cord-005646-xhx9pzhj 3141 27 therapy therapy NN cord-005646-xhx9pzhj 3141 28 , , , cord-005646-xhx9pzhj 3141 29 has have VBZ cord-005646-xhx9pzhj 3141 30 included include VBN cord-005646-xhx9pzhj 3141 31 ECMO ECMO NNP cord-005646-xhx9pzhj 3141 32 since since IN cord-005646-xhx9pzhj 3141 33 1986 1986 CD cord-005646-xhx9pzhj 3141 34 and and CC cord-005646-xhx9pzhj 3141 35 high high JJ cord-005646-xhx9pzhj 3141 36 frequency frequency NN cord-005646-xhx9pzhj 3141 37 oscillatory oscillatory JJ cord-005646-xhx9pzhj 3141 38 ventilation ventilation NN cord-005646-xhx9pzhj 3141 39 since since IN cord-005646-xhx9pzhj 3141 40 1992 1992 CD cord-005646-xhx9pzhj 3141 41 . . . cord-005646-xhx9pzhj 3142 1 iNO iNO NNP cord-005646-xhx9pzhj 3142 2 has have VBZ cord-005646-xhx9pzhj 3142 3 been be VBN cord-005646-xhx9pzhj 3142 4 in in IN cord-005646-xhx9pzhj 3142 5 experimental experimental JJ cord-005646-xhx9pzhj 3142 6 use use NN cord-005646-xhx9pzhj 3142 7 at at IN cord-005646-xhx9pzhj 3142 8 CHW CHW NNP cord-005646-xhx9pzhj 3142 9 since since IN cord-005646-xhx9pzhj 3142 10 May May NNP cord-005646-xhx9pzhj 3142 11 of of IN cord-005646-xhx9pzhj 3142 12 I994 I994 NNP cord-005646-xhx9pzhj 3142 13 and and CC cord-005646-xhx9pzhj 3142 14 has have VBZ cord-005646-xhx9pzhj 3142 15 resulted result VBN cord-005646-xhx9pzhj 3142 16 in in IN cord-005646-xhx9pzhj 3142 17 the the DT cord-005646-xhx9pzhj 3142 18 perception perception NN cord-005646-xhx9pzhj 3142 19 of of IN cord-005646-xhx9pzhj 3142 20 a a DT cord-005646-xhx9pzhj 3142 21 decreased decreased JJ cord-005646-xhx9pzhj 3142 22 need need NN cord-005646-xhx9pzhj 3142 23 for for IN cord-005646-xhx9pzhj 3142 24 ECMO ecmo NN cord-005646-xhx9pzhj 3142 25 therapy therapy NN cord-005646-xhx9pzhj 3142 26 in in IN cord-005646-xhx9pzhj 3142 27 those those DT cord-005646-xhx9pzhj 3142 28 patients patient NNS cord-005646-xhx9pzhj 3142 29 referred refer VBD cord-005646-xhx9pzhj 3142 30 for for IN cord-005646-xhx9pzhj 3142 31 rescue rescue NN cord-005646-xhx9pzhj 3142 32 therapy therapy NN cord-005646-xhx9pzhj 3142 33 . . . cord-005646-xhx9pzhj 3143 1 This this DT cord-005646-xhx9pzhj 3143 2 study study NN cord-005646-xhx9pzhj 3143 3 was be VBD cord-005646-xhx9pzhj 3143 4 designed design VBN cord-005646-xhx9pzhj 3143 5 to to TO cord-005646-xhx9pzhj 3143 6 tbst tbst VB cord-005646-xhx9pzhj 3143 7 the the DT cord-005646-xhx9pzhj 3143 8 validity validity NN cord-005646-xhx9pzhj 3143 9 of of IN cord-005646-xhx9pzhj 3143 10 that that DT cord-005646-xhx9pzhj 3143 11 perception perception NN cord-005646-xhx9pzhj 3143 12 . . . cord-005646-xhx9pzhj 3144 1 Study study NN cord-005646-xhx9pzhj 3144 2 Type type NN cord-005646-xhx9pzhj 3144 3 : : : cord-005646-xhx9pzhj 3144 4 Retrospective retrospective JJ cord-005646-xhx9pzhj 3144 5 cohort cohort NN cord-005646-xhx9pzhj 3144 6 . . . cord-005646-xhx9pzhj 3145 1 Methods method NNS cord-005646-xhx9pzhj 3145 2 : : : cord-005646-xhx9pzhj 3146 1 The the DT cord-005646-xhx9pzhj 3146 2 medical medical JJ cord-005646-xhx9pzhj 3146 3 records record NNS cord-005646-xhx9pzhj 3146 4 of of IN cord-005646-xhx9pzhj 3146 5 all all DT cord-005646-xhx9pzhj 3146 6 105 105 CD cord-005646-xhx9pzhj 3146 7 patients patient NNS cord-005646-xhx9pzhj 3146 8 referred refer VBN cord-005646-xhx9pzhj 3146 9 to to IN cord-005646-xhx9pzhj 3146 10 CHW CHW NNP cord-005646-xhx9pzhj 3146 11 from from IN cord-005646-xhx9pzhj 3146 12 1 1 CD cord-005646-xhx9pzhj 3146 13 / / SYM cord-005646-xhx9pzhj 3146 14 lj93 lj93 NNS cord-005646-xhx9pzhj 3146 15 to to IN cord-005646-xhx9pzhj 3146 16 4/1/95 4/1/95 CD cord-005646-xhx9pzhj 3146 17 for for IN cord-005646-xhx9pzhj 3146 18 rescue rescue NN cord-005646-xhx9pzhj 3146 19 therapy therapy NN cord-005646-xhx9pzhj 3146 20 for for IN cord-005646-xhx9pzhj 3146 21 severe severe JJ cord-005646-xhx9pzhj 3146 22 respiratory respiratory JJ cord-005646-xhx9pzhj 3146 23 failure failure NN cord-005646-xhx9pzhj 3146 24 were be VBD cord-005646-xhx9pzhj 3146 25 included include VBN cord-005646-xhx9pzhj 3146 26 in in IN cord-005646-xhx9pzhj 3146 27 the the DT cord-005646-xhx9pzhj 3146 28 chart chart NN cord-005646-xhx9pzhj 3146 29 review review NN cord-005646-xhx9pzhj 3146 30 . . . cord-005646-xhx9pzhj 3147 1 Data datum NNS cord-005646-xhx9pzhj 3147 2 were be VBD cord-005646-xhx9pzhj 3147 3 collected collect VBN cord-005646-xhx9pzhj 3147 4 regarding regard VBG cord-005646-xhx9pzhj 3147 5 diagnoses diagnosis NNS cord-005646-xhx9pzhj 3147 6 , , , cord-005646-xhx9pzhj 3147 7 illness illness NN cord-005646-xhx9pzhj 3147 8 severity severity NN cord-005646-xhx9pzhj 3147 9 , , , cord-005646-xhx9pzhj 3147 10 hospital hospital NN cord-005646-xhx9pzhj 3147 11 course course NN cord-005646-xhx9pzhj 3147 12 including include VBG cord-005646-xhx9pzhj 3147 13 interventions intervention NNS cord-005646-xhx9pzhj 3147 14 and and CC cord-005646-xhx9pzhj 3147 15 complications complication NNS cord-005646-xhx9pzhj 3147 16 , , , cord-005646-xhx9pzhj 3147 17 and and CC cord-005646-xhx9pzhj 3147 18 outcomes outcome NNS cord-005646-xhx9pzhj 3147 19 . . . cord-005646-xhx9pzhj 3148 1 Exclusion exclusion NN cord-005646-xhx9pzhj 3148 2 criteria criterion NNS cord-005646-xhx9pzhj 3149 1 w w NNP cord-005646-xhx9pzhj 3150 1 ~ere ~ere NNP cord-005646-xhx9pzhj 3150 2 the the DT cord-005646-xhx9pzhj 3150 3 finding finding NN cord-005646-xhx9pzhj 3150 4 of of IN cord-005646-xhx9pzhj 3150 5 structural structural JJ cord-005646-xhx9pzhj 3150 6 heart heart NN cord-005646-xhx9pzhj 3150 7 disease disease NN cord-005646-xhx9pzhj 3150 8 or or CC cord-005646-xhx9pzhj 3150 9 congenital congenital JJ cord-005646-xhx9pzhj 3150 10 diaphragmatic diaphragmatic JJ cord-005646-xhx9pzhj 3150 11 hernia hernia NN cord-005646-xhx9pzhj 3150 12 as as IN cord-005646-xhx9pzhj 3150 13 the the DT cord-005646-xhx9pzhj 3150 14 basis basis NN cord-005646-xhx9pzhj 3150 15 for for IN cord-005646-xhx9pzhj 3150 16 hypoxemia hypoxemia NN cord-005646-xhx9pzhj 3150 17 . . . cord-005646-xhx9pzhj 3151 1 Qualification qualification NN cord-005646-xhx9pzhj 3151 2 for for IN cord-005646-xhx9pzhj 3151 3 iNO iNO NNS cord-005646-xhx9pzhj 3151 4 treatment treatment NN cord-005646-xhx9pzhj 3151 5 included include VBD cord-005646-xhx9pzhj 3151 6 an an DT cord-005646-xhx9pzhj 3151 7 A A NNP cord-005646-xhx9pzhj 3151 8 - - HYPH cord-005646-xhx9pzhj 3151 9 aDO2 ado2 NN cord-005646-xhx9pzhj 3151 10 -600 -600 NN cord-005646-xhx9pzhj 3151 11 or or CC cord-005646-xhx9pzhj 3151 12 OI OI NNP cord-005646-xhx9pzhj 3151 13 ~-40 ~-40 CD cord-005646-xhx9pzhj 3151 14 for for IN cord-005646-xhx9pzhj 3151 15 two two CD cord-005646-xhx9pzhj 3151 16 hours hour NNS cord-005646-xhx9pzhj 3151 17 or or CC cord-005646-xhx9pzhj 3151 18 - - : cord-005646-xhx9pzhj 3151 19 > > SYM cord-005646-xhx9pzhj 3151 20 25 25 CD cord-005646-xhx9pzhj 3151 21 for for IN cord-005646-xhx9pzhj 3151 22 twelve twelve CD cord-005646-xhx9pzhj 3151 23 hours hour NNS cord-005646-xhx9pzhj 3151 24 and and CC cord-005646-xhx9pzhj 3151 25 echocardiographic echocardiographic JJ cord-005646-xhx9pzhj 3151 26 demonstration demonstration NN cord-005646-xhx9pzhj 3151 27 of of IN cord-005646-xhx9pzhj 3151 28 persistent persistent JJ cord-005646-xhx9pzhj 3151 29 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3151 30 hypertension hypertension NN cord-005646-xhx9pzhj 3151 31 of of IN cord-005646-xhx9pzhj 3151 32 the the DT cord-005646-xhx9pzhj 3151 33 newborn newborn NN cord-005646-xhx9pzhj 3151 34 . . . cord-005646-xhx9pzhj 3152 1 Patients patient NNS cord-005646-xhx9pzhj 3152 2 were be VBD cord-005646-xhx9pzhj 3152 3 classified classify VBN cord-005646-xhx9pzhj 3152 4 into into IN cord-005646-xhx9pzhj 3152 5 two two CD cord-005646-xhx9pzhj 3152 6 groups group NNS cord-005646-xhx9pzhj 3152 7 based base VBN cord-005646-xhx9pzhj 3152 8 on on IN cord-005646-xhx9pzhj 3152 9 the the DT cord-005646-xhx9pzhj 3152 10 availability availability NN cord-005646-xhx9pzhj 3152 11 of of IN cord-005646-xhx9pzhj 3152 12 iNO iNO NNS cord-005646-xhx9pzhj 3152 13 at at IN cord-005646-xhx9pzhj 3152 14 the the DT cord-005646-xhx9pzhj 3152 15 time time NN cord-005646-xhx9pzhj 3152 16 of of IN cord-005646-xhx9pzhj 3152 17 their -PRON- PRP$ cord-005646-xhx9pzhj 3152 18 hospitalization hospitalization NN cord-005646-xhx9pzhj 3152 19 . . . cord-005646-xhx9pzhj 3153 1 Results result NNS cord-005646-xhx9pzhj 3153 2 : : : cord-005646-xhx9pzhj 3154 1 In in IN cord-005646-xhx9pzhj 3154 2 the the DT cord-005646-xhx9pzhj 3154 3 time time NN cord-005646-xhx9pzhj 3154 4 period period NN cord-005646-xhx9pzhj 3154 5 of of IN cord-005646-xhx9pzhj 3154 6 the the DT cord-005646-xhx9pzhj 3154 7 study study NN cord-005646-xhx9pzhj 3154 8 , , , cord-005646-xhx9pzhj 3154 9 105 105 CD cord-005646-xhx9pzhj 3154 10 patients patient NNS cord-005646-xhx9pzhj 3154 11 were be VBD cord-005646-xhx9pzhj 3154 12 referred refer VBN cord-005646-xhx9pzhj 3154 13 for for IN cord-005646-xhx9pzhj 3154 14 possible possible JJ cord-005646-xhx9pzhj 3154 15 ECMO ecmo NN cord-005646-xhx9pzhj 3154 16 therapy therapy NN cord-005646-xhx9pzhj 3154 17 . . . cord-005646-xhx9pzhj 3155 1 Twelve twelve CD cord-005646-xhx9pzhj 3155 2 patients patient NNS cord-005646-xhx9pzhj 3155 3 greater great JJR cord-005646-xhx9pzhj 3155 4 than than IN cord-005646-xhx9pzhj 3155 5 4 4 CD cord-005646-xhx9pzhj 3155 6 weeks week NNS cord-005646-xhx9pzhj 3155 7 old old JJ cord-005646-xhx9pzhj 3155 8 , , , cord-005646-xhx9pzhj 3155 9 31 31 CD cord-005646-xhx9pzhj 3155 10 with with IN cord-005646-xhx9pzhj 3155 11 congenital congenital JJ cord-005646-xhx9pzhj 3155 12 diaphragmatic diaphragmatic JJ cord-005646-xhx9pzhj 3155 13 hernia hernia NN cord-005646-xhx9pzhj 3155 14 and and CC cord-005646-xhx9pzhj 3155 15 12 12 CD cord-005646-xhx9pzhj 3155 16 with with IN cord-005646-xhx9pzhj 3155 17 congenital congenital JJ cord-005646-xhx9pzhj 3155 18 heart heart NN cord-005646-xhx9pzhj 3155 19 disease disease NN cord-005646-xhx9pzhj 3155 20 were be VBD cord-005646-xhx9pzhj 3155 21 excluded exclude VBN cord-005646-xhx9pzhj 3155 22 from from IN cord-005646-xhx9pzhj 3155 23 this this DT cord-005646-xhx9pzhj 3155 24 analysis analysis NN cord-005646-xhx9pzhj 3155 25 , , , cord-005646-xhx9pzhj 3155 26 leaving leave VBG cord-005646-xhx9pzhj 3155 27 50 50 CD cord-005646-xhx9pzhj 3155 28 patients patient NNS cord-005646-xhx9pzhj 3155 29 for for IN cord-005646-xhx9pzhj 3155 30 study study NN cord-005646-xhx9pzhj 3155 31 , , , cord-005646-xhx9pzhj 3155 32 iNO iNO NNS cord-005646-xhx9pzhj 3155 33 availability availability NN cord-005646-xhx9pzhj 3155 34 reduced reduce VBN cord-005646-xhx9pzhj 3155 35 ECMO ECMO NNP cord-005646-xhx9pzhj 3155 36 use use NN cord-005646-xhx9pzhj 3155 37 from from IN cord-005646-xhx9pzhj 3155 38 16 16 CD cord-005646-xhx9pzhj 3155 39 of of IN cord-005646-xhx9pzhj 3155 40 34 34 CD cord-005646-xhx9pzhj 3155 41 ( ( -LRB- cord-005646-xhx9pzhj 3155 42 47 47 CD cord-005646-xhx9pzhj 3155 43 % % NN cord-005646-xhx9pzhj 3155 44 ) ) -RRB- cord-005646-xhx9pzhj 3155 45 patients patient NNS cord-005646-xhx9pzhj 3155 46 in in IN cord-005646-xhx9pzhj 3155 47 the the DT cord-005646-xhx9pzhj 3155 48 ~iNO ~iNO NNP cord-005646-xhx9pzhj 3155 49 unavailable unavailable JJ cord-005646-xhx9pzhj 3155 50 " " `` cord-005646-xhx9pzhj 3155 51 group group NN cord-005646-xhx9pzhj 3155 52 to to IN cord-005646-xhx9pzhj 3155 53 2 2 CD cord-005646-xhx9pzhj 3155 54 out out IN cord-005646-xhx9pzhj 3155 55 of of IN cord-005646-xhx9pzhj 3155 56 16 16 CD cord-005646-xhx9pzhj 3155 57 ( ( -LRB- cord-005646-xhx9pzhj 3155 58 12.5 12.5 CD cord-005646-xhx9pzhj 3155 59 % % NN cord-005646-xhx9pzhj 3155 60 ) ) -RRB- cord-005646-xhx9pzhj 3155 61 patients patient NNS cord-005646-xhx9pzhj 3155 62 in in IN cord-005646-xhx9pzhj 3155 63 the the DT cord-005646-xhx9pzhj 3155 64 " " `` cord-005646-xhx9pzhj 3155 65 iNO iNO NNS cord-005646-xhx9pzhj 3155 66 available available JJ cord-005646-xhx9pzhj 3155 67 " " '' cord-005646-xhx9pzhj 3155 68 group group NN cord-005646-xhx9pzhj 3155 69 , , , cord-005646-xhx9pzhj 3155 70 p=&026 p=&026 NN cord-005646-xhx9pzhj 3155 71 by by IN cord-005646-xhx9pzhj 3155 72 Fisher Fisher NNP cord-005646-xhx9pzhj 3155 73 's 's POS cord-005646-xhx9pzhj 3155 74 exact exact JJ cord-005646-xhx9pzhj 3155 75 test test NN cord-005646-xhx9pzhj 3155 76 . . . cord-005646-xhx9pzhj 3156 1 The the DT cord-005646-xhx9pzhj 3156 2 fact fact NN cord-005646-xhx9pzhj 3156 3 that that IN cord-005646-xhx9pzhj 3156 4 the the DT cord-005646-xhx9pzhj 3156 5 two two CD cord-005646-xhx9pzhj 3156 6 groups group NNS cord-005646-xhx9pzhj 3156 7 were be VBD cord-005646-xhx9pzhj 3156 8 composed compose VBN cord-005646-xhx9pzhj 3156 9 of of IN cord-005646-xhx9pzhj 3156 10 patients patient NNS cord-005646-xhx9pzhj 3156 11 of of IN cord-005646-xhx9pzhj 3156 12 similar similar JJ cord-005646-xhx9pzhj 3156 13 severity severity NN cord-005646-xhx9pzhj 3156 14 of of IN cord-005646-xhx9pzhj 3156 15 illness illness NN cord-005646-xhx9pzhj 3156 16 is be VBZ cord-005646-xhx9pzhj 3156 17 reflected reflect VBN cord-005646-xhx9pzhj 3156 18 by by IN cord-005646-xhx9pzhj 3156 19 comparable comparable JJ cord-005646-xhx9pzhj 3156 20 rates rate NNS cord-005646-xhx9pzhj 3156 21 of of IN cord-005646-xhx9pzhj 3156 22 ECMO ECMO NNP cord-005646-xhx9pzhj 3156 23 and and CC cord-005646-xhx9pzhj 3156 24 iNO iNO NNP cord-005646-xhx9pzhj 3156 25 rescue rescue NN cord-005646-xhx9pzhj 3156 26 therapy therapy NN cord-005646-xhx9pzhj 3156 27 ( ( -LRB- cord-005646-xhx9pzhj 3156 28 47 47 CD cord-005646-xhx9pzhj 3156 29 % % NN cord-005646-xhx9pzhj 3156 30 vs. vs. NN cord-005646-xhx9pzhj 3156 31 56 56 CD cord-005646-xhx9pzhj 3156 32 % % NN cord-005646-xhx9pzhj 3156 33 ) ) -RRB- cord-005646-xhx9pzhj 3156 34 . . . cord-005646-xhx9pzhj 3157 1 Conclusion conclusion NN cord-005646-xhx9pzhj 3157 2 : : : cord-005646-xhx9pzhj 3157 3 By by IN cord-005646-xhx9pzhj 3157 4 providing provide VBG cord-005646-xhx9pzhj 3157 5 an an DT cord-005646-xhx9pzhj 3157 6 alternative alternative JJ cord-005646-xhx9pzhj 3157 7 rescue rescue NN cord-005646-xhx9pzhj 3157 8 therapy therapy NN cord-005646-xhx9pzhj 3157 9 , , , cord-005646-xhx9pzhj 3157 10 iNO iNO NNP cord-005646-xhx9pzhj 3157 11 has have VBZ cord-005646-xhx9pzhj 3157 12 reduced reduce VBN cord-005646-xhx9pzhj 3157 13 the the DT cord-005646-xhx9pzhj 3157 14 need need NN cord-005646-xhx9pzhj 3157 15 for for IN cord-005646-xhx9pzhj 3157 16 ECMO ECMO NNP cord-005646-xhx9pzhj 3157 17 in in IN cord-005646-xhx9pzhj 3157 18 this this DT cord-005646-xhx9pzhj 3157 19 group group NN cord-005646-xhx9pzhj 3157 20 of of IN cord-005646-xhx9pzhj 3157 21 neonates neonate NNS cord-005646-xhx9pzhj 3157 22 referred refer VBN cord-005646-xhx9pzhj 3157 23 for for IN cord-005646-xhx9pzhj 3157 24 respiratory respiratory JJ cord-005646-xhx9pzhj 3157 25 failure failure NN cord-005646-xhx9pzhj 3157 26 . . . cord-005646-xhx9pzhj 3158 1 Introduction introduction NN cord-005646-xhx9pzhj 3158 2 : : : cord-005646-xhx9pzhj 3158 3 true true JJ cord-005646-xhx9pzhj 3158 4 hepatnrenal hepatnrenal JJ cord-005646-xhx9pzhj 3158 5 syndrome syndrome NN cord-005646-xhx9pzhj 3158 6 ( ( -LRB- cord-005646-xhx9pzhj 3158 7 HIS HIS NNP cord-005646-xhx9pzhj 3158 8 ) ) -RRB- cord-005646-xhx9pzhj 3159 1 is be VBZ cord-005646-xhx9pzhj 3159 2 defined define VBN cord-005646-xhx9pzhj 3159 3 an an DT cord-005646-xhx9pzhj 3159 4 acute acute JJ cord-005646-xhx9pzhj 3159 5 renal renal JJ cord-005646-xhx9pzhj 3159 6 failure failure NN cord-005646-xhx9pzhj 3159 7 { { -LRB- cord-005646-xhx9pzhj 3159 8 ARF ARF NNP cord-005646-xhx9pzhj 3159 9 ) ) -RRB- cord-005646-xhx9pzhj 3159 10 in in IN cord-005646-xhx9pzhj 3159 11 the the DT cord-005646-xhx9pzhj 3159 12 presence presence NN cord-005646-xhx9pzhj 3159 13 of of IN cord-005646-xhx9pzhj 3159 14 severe severe JJ cord-005646-xhx9pzhj 3159 15 liver liver NN cord-005646-xhx9pzhj 3159 16 disease disease NN cord-005646-xhx9pzhj 3159 17 without without IN cord-005646-xhx9pzhj 3159 18 other other JJ cord-005646-xhx9pzhj 3159 19 known know VBN cord-005646-xhx9pzhj 3159 20 causes cause NNS cord-005646-xhx9pzhj 3159 21 of of IN cord-005646-xhx9pzhj 3159 22 renal renal JJ cord-005646-xhx9pzhj 3159 23 failure failure NN cord-005646-xhx9pzhj 3159 24 . . . cord-005646-xhx9pzhj 3160 1 HRS hrs NN cord-005646-xhx9pzhj 3160 2 is be VBZ cord-005646-xhx9pzhj 3160 3 frequently frequently RB cord-005646-xhx9pzhj 3160 4 seen see VBN cord-005646-xhx9pzhj 3160 5 in in IN cord-005646-xhx9pzhj 3160 6 the the DT cord-005646-xhx9pzhj 3160 7 course course NN cord-005646-xhx9pzhj 3160 8 of of IN cord-005646-xhx9pzhj 3160 9 hepatic hepatic JJ cord-005646-xhx9pzhj 3160 10 cirrhosis• cirrhosis• NN cord-005646-xhx9pzhj 3161 1 In in IN cord-005646-xhx9pzhj 3161 2 children child NNS cord-005646-xhx9pzhj 3161 3 , , , cord-005646-xhx9pzhj 3161 4 cirrhosis cirrhosis NN cord-005646-xhx9pzhj 3161 5 is be VBZ cord-005646-xhx9pzhj 3161 6 rare rare JJ cord-005646-xhx9pzhj 3161 7 ; ; : cord-005646-xhx9pzhj 3161 8 however however RB cord-005646-xhx9pzhj 3161 9 , , , cord-005646-xhx9pzhj 3161 10 ARF ARF NNP cord-005646-xhx9pzhj 3161 11 can can MD cord-005646-xhx9pzhj 3161 12 be be VB cord-005646-xhx9pzhj 3161 13 seen see VBN cord-005646-xhx9pzhj 3161 14 in in IN cord-005646-xhx9pzhj 3161 15 combination combination NN cord-005646-xhx9pzhj 3161 16 with with IN cord-005646-xhx9pzhj 3161 17 aseites aseite NNS cord-005646-xhx9pzhj 3161 18 and and CC cord-005646-xhx9pzhj 3161 19 liver liver NN cord-005646-xhx9pzhj 3162 1 dysfunction• dysfunction• NNP cord-005646-xhx9pzhj 3163 1 We -PRON- PRP cord-005646-xhx9pzhj 3163 2 describe describe VBP cord-005646-xhx9pzhj 3163 3 3 3 CD cord-005646-xhx9pzhj 3163 4 patients patient NNS cord-005646-xhx9pzhj 3163 5 with with IN cord-005646-xhx9pzhj 3163 6 hepatic hepatic JJ cord-005646-xhx9pzhj 3163 7 dysfunction dysfunction NN cord-005646-xhx9pzhj 3163 8 and and CC cord-005646-xhx9pzhj 3163 9 aseites aseite NNS cord-005646-xhx9pzhj 3163 10 in in IN cord-005646-xhx9pzhj 3163 11 combination combination NN cord-005646-xhx9pzhj 3163 12 with with IN cord-005646-xhx9pzhj 3163 13 AR~ AR~ NNP cord-005646-xhx9pzhj 3163 14 and and CC cord-005646-xhx9pzhj 3163 15 abnormal abnormal JJ cord-005646-xhx9pzhj 3163 16 sodium sodium NN cord-005646-xhx9pzhj 3163 17 - - HYPH cord-005646-xhx9pzhj 3163 18 water water NN cord-005646-xhx9pzhj 3163 19 handling handling NN cord-005646-xhx9pzhj 3163 20 , , , cord-005646-xhx9pzhj 3163 21 leading lead VBG cord-005646-xhx9pzhj 3163 22 to to IN cord-005646-xhx9pzhj 3163 23 the the DT cord-005646-xhx9pzhj 3163 24 diagnosis diagnosis NN cord-005646-xhx9pzhj 3163 25 of of IN cord-005646-xhx9pzhj 3163 26 HRS HRS NNP cord-005646-xhx9pzhj 3163 27 . . . cord-005646-xhx9pzhj 3164 1 Pathophysiology pathophysiology NN cord-005646-xhx9pzhj 3164 2 : : : cord-005646-xhx9pzhj 3165 1 three three CD cord-005646-xhx9pzhj 3165 2 factors factor NNS cord-005646-xhx9pzhj 3165 3 are be VBP cord-005646-xhx9pzhj 3165 4 considered consider VBN cord-005646-xhx9pzhj 3165 5 in in IN cord-005646-xhx9pzhj 3165 6 the the DT cord-005646-xhx9pzhj 3165 7 pathogenesis pathogenesis NN cord-005646-xhx9pzhj 3165 8 of of IN cord-005646-xhx9pzhj 3165 9 HR~ HR~ NNP cord-005646-xhx9pzhj 3165 10 : : : cord-005646-xhx9pzhj 3166 1 I -PRON- PRP cord-005646-xhx9pzhj 3166 2 ) ) -RRB- cord-005646-xhx9pzhj 3166 3 hepatic hepatic JJ cord-005646-xhx9pzhj 3166 4 dysfunction dysfunction NN cord-005646-xhx9pzhj 3166 5 , , , cord-005646-xhx9pzhj 3166 6 2 2 CD cord-005646-xhx9pzhj 3166 7 ) ) -RRB- cord-005646-xhx9pzhj 3166 8 deranged deranged JJ cord-005646-xhx9pzhj 3166 9 hemodynamics hemodynamic NNS cord-005646-xhx9pzhj 3166 10 , , , cord-005646-xhx9pzhj 3166 11 including include VBG cord-005646-xhx9pzhj 3166 12 abnormal abnormal JJ cord-005646-xhx9pzhj 3166 13 blood blood NN cord-005646-xhx9pzhj 3166 14 pressure pressure NN cord-005646-xhx9pzhj 3166 15 , , , cord-005646-xhx9pzhj 3166 16 reduced reduce VBN cord-005646-xhx9pzhj 3166 17 effective effective JJ cord-005646-xhx9pzhj 3166 18 arterial arterial JJ cord-005646-xhx9pzhj 3166 19 blood blood NN cord-005646-xhx9pzhj 3166 20 volume volume NN cord-005646-xhx9pzhj 3166 21 and and CC cord-005646-xhx9pzhj 3166 22 abnormal abnormal JJ cord-005646-xhx9pzhj 3166 23 blood blood NN cord-005646-xhx9pzhj 3166 24 flew fly VBD cord-005646-xhx9pzhj 3166 25 distribution distribution NN cord-005646-xhx9pzhj 3166 26 , , , cord-005646-xhx9pzhj 3166 27 and and CC cord-005646-xhx9pzhj 3166 28 3 3 LS cord-005646-xhx9pzhj 3166 29 ) ) -RRB- cord-005646-xhx9pzhj 3166 30 neuro neuro JJ cord-005646-xhx9pzhj 3166 31 - - HYPH cord-005646-xhx9pzhj 3166 32 humoral humoral JJ cord-005646-xhx9pzhj 3166 33 dysrsgulatiom dysrsgulatiom NNP cord-005646-xhx9pzhj 3166 34 , , , cord-005646-xhx9pzhj 3166 35 including include VBG cord-005646-xhx9pzhj 3166 36 elevated elevated JJ cord-005646-xhx9pzhj 3166 37 levels level NNS cord-005646-xhx9pzhj 3166 38 of of IN cord-005646-xhx9pzhj 3166 39 aldosteron aldosteron NNP cord-005646-xhx9pzhj 3166 40 , , , cord-005646-xhx9pzhj 3166 41 renin renin NN cord-005646-xhx9pzhj 3166 42 , , , cord-005646-xhx9pzhj 3166 43 angiotensin angiotensin NN cord-005646-xhx9pzhj 3166 44 - - HYPH cord-005646-xhx9pzhj 3166 45 ll ll NN cord-005646-xhx9pzhj 3166 46 , , , cord-005646-xhx9pzhj 3166 47 ADE ADE NNP cord-005646-xhx9pzhj 3166 48 , , , cord-005646-xhx9pzhj 3166 49 vasodilatim vasodilatim NNP cord-005646-xhx9pzhj 3166 50 9 9 CD cord-005646-xhx9pzhj 3166 51 nitric nitric NN cord-005646-xhx9pzhj 3166 52 oxide oxide NN cord-005646-xhx9pzhj 3166 53 and and CC cord-005646-xhx9pzhj 3166 54 vasoconstrictor vasoconstrictor NN cord-005646-xhx9pzhj 3166 55 peptide peptide NN cord-005646-xhx9pzhj 3166 56 endothelin endothelin NNP cord-005646-xhx9pzhj 3166 57 - - HYPH cord-005646-xhx9pzhj 3166 58 l l NN cord-005646-xhx9pzhj 3166 59 . . . cord-005646-xhx9pzhj 3167 1 The the DT cord-005646-xhx9pzhj 3167 2 main main JJ cord-005646-xhx9pzhj 3167 3 pathogenetic pathogenetic JJ cord-005646-xhx9pzhj 3167 4 feature feature NN cord-005646-xhx9pzhj 3167 5 is be VBZ cord-005646-xhx9pzhj 3167 6 decreased decrease VBN cord-005646-xhx9pzhj 3167 7 cortical cortical JJ cord-005646-xhx9pzhj 3167 8 renal renal JJ cord-005646-xhx9pzhj 3167 9 blood blood NN cord-005646-xhx9pzhj 3167 10 flow flow NN cord-005646-xhx9pzhj 3167 11 , , , cord-005646-xhx9pzhj 3167 12 decrease decrease NN cord-005646-xhx9pzhj 3167 13 of of IN cord-005646-xhx9pzhj 3167 14 glomerulur glomerulur NN cord-005646-xhx9pzhj 3167 15 filtration filtration NN cord-005646-xhx9pzhj 3167 16 rate rate NN cord-005646-xhx9pzhj 3167 17 ( ( -LRB- cord-005646-xhx9pzhj 3167 18 GFR GFR NNP cord-005646-xhx9pzhj 3167 19 ) ) -RRB- cord-005646-xhx9pzhj 3167 20 , , , cord-005646-xhx9pzhj 3167 21 vastly vastly RB cord-005646-xhx9pzhj 3167 22 increased increase VBN cord-005646-xhx9pzhj 3167 23 sodium sodium NN cord-005646-xhx9pzhj 3167 24 retention retention NN cord-005646-xhx9pzhj 3167 25 , , , cord-005646-xhx9pzhj 3167 26 uliguria uliguria NNP cord-005646-xhx9pzhj 3167 27 , , , cord-005646-xhx9pzhj 3167 28 and and CC cord-005646-xhx9pzhj 3167 29 azotemia azotemia NN cord-005646-xhx9pzhj 3167 30 . . . cord-005646-xhx9pzhj 3168 1 Treatment treatment NN cord-005646-xhx9pzhj 3168 2 : : : cord-005646-xhx9pzhj 3168 3 therapy therapy NN cord-005646-xhx9pzhj 3168 4 is be VBZ cord-005646-xhx9pzhj 3168 5 based base VBN cord-005646-xhx9pzhj 3168 6 on on IN cord-005646-xhx9pzhj 3168 7 counteracting counteract VBG cord-005646-xhx9pzhj 3168 8 sodium sodium NN cord-005646-xhx9pzhj 3168 9 and and CC cord-005646-xhx9pzhj 3168 10 fluid fluid JJ cord-005646-xhx9pzhj 3168 11 retention retention NN cord-005646-xhx9pzhj 3168 12 by by IN cord-005646-xhx9pzhj 3168 13 highdose highdose NNP cord-005646-xhx9pzhj 3168 14 aldosteron aldosteron NNP cord-005646-xhx9pzhj 3168 15 antagonists antagonist NNS cord-005646-xhx9pzhj 3168 16 and and CC cord-005646-xhx9pzhj 3168 17 loop loop NN cord-005646-xhx9pzhj 3168 18 diuretics diuretic NNS cord-005646-xhx9pzhj 3168 19 , , , cord-005646-xhx9pzhj 3168 20 improving improve VBG cord-005646-xhx9pzhj 3168 21 renal renal JJ cord-005646-xhx9pzhj 3168 22 perfusion perfusion NN cord-005646-xhx9pzhj 3168 23 by by IN cord-005646-xhx9pzhj 3168 24 lowdose lowdose NNP cord-005646-xhx9pzhj 3168 25 dopamin dopamin NNP cord-005646-xhx9pzhj 3168 26 , , , cord-005646-xhx9pzhj 3168 27 and and CC cord-005646-xhx9pzhj 3168 28 strict strict JJ cord-005646-xhx9pzhj 3168 29 restriction restriction NN cord-005646-xhx9pzhj 3168 30 of of IN cord-005646-xhx9pzhj 3168 31 fluid fluid NN cord-005646-xhx9pzhj 3168 32 and and CC cord-005646-xhx9pzhj 3168 33 sodium sodium NN cord-005646-xhx9pzhj 3168 34 . . . cord-005646-xhx9pzhj 3169 1 Interventions intervention NNS cord-005646-xhx9pzhj 3169 2 as as IN cord-005646-xhx9pzhj 3169 3 paracenteals paracenteal NNS cord-005646-xhx9pzhj 3169 4 of of IN cord-005646-xhx9pzhj 3169 5 aacites aacite NNS cord-005646-xhx9pzhj 3169 6 or or CC cord-005646-xhx9pzhj 3169 7 n n NNP cord-005646-xhx9pzhj 3169 8 peritoneo- peritoneo- NN cord-005646-xhx9pzhj 3170 1 systemic systemic JJ cord-005646-xhx9pzhj 3170 2 shunt shunt NN cord-005646-xhx9pzhj 3170 3 are be VBP cord-005646-xhx9pzhj 3170 4 associated associate VBN cord-005646-xhx9pzhj 3170 5 with with IN cord-005646-xhx9pzhj 3170 6 high high JJ cord-005646-xhx9pzhj 3170 7 morbidity morbidity NN cord-005646-xhx9pzhj 3170 8 and and CC cord-005646-xhx9pzhj 3170 9 poor poor JJ cord-005646-xhx9pzhj 3170 10 outcome outcome NN cord-005646-xhx9pzhj 3170 11 in in IN cord-005646-xhx9pzhj 3170 12 children child NNS cord-005646-xhx9pzhj 3170 13 . . . cord-005646-xhx9pzhj 3171 1 Reversal reversal NN cord-005646-xhx9pzhj 3171 2 of of IN cord-005646-xhx9pzhj 3171 3 HEm HEm NNS cord-005646-xhx9pzhj 3171 4 by by IN cord-005646-xhx9pzhj 3171 5 conservative conservative JJ cord-005646-xhx9pzhj 3171 6 measures measure NNS cord-005646-xhx9pzhj 3171 7 can can MD cord-005646-xhx9pzhj 3171 8 only only RB cord-005646-xhx9pzhj 3171 9 be be VB cord-005646-xhx9pzhj 3171 10 attained attain VBN cord-005646-xhx9pzhj 3171 11 at at IN cord-005646-xhx9pzhj 3171 12 early early JJ cord-005646-xhx9pzhj 3171 13 stages stage NNS cord-005646-xhx9pzhj 3171 14 of of IN cord-005646-xhx9pzhj 3171 15 HRL HRL NNP cord-005646-xhx9pzhj 3171 16 Liver Liver NNP cord-005646-xhx9pzhj 3171 17 transplantation transplantation NN cord-005646-xhx9pzhj 3171 18 is be VBZ cord-005646-xhx9pzhj 3171 19 the the DT cord-005646-xhx9pzhj 3171 20 only only JJ cord-005646-xhx9pzhj 3171 21 definitive definitive JJ cord-005646-xhx9pzhj 3171 22 treatment treatment NN cord-005646-xhx9pzhj 3171 23 that that WDT cord-005646-xhx9pzhj 3171 24 can can MD cord-005646-xhx9pzhj 3171 25 reverse reverse VB cord-005646-xhx9pzhj 3171 26 ERE ERE NNP cord-005646-xhx9pzhj 3171 27 at at IN cord-005646-xhx9pzhj 3171 28 advanced advanced JJ cord-005646-xhx9pzhj 3171 29 stages stage NNS cord-005646-xhx9pzhj 3171 30 . . . cord-005646-xhx9pzhj 3172 1 Patients patient NNS cord-005646-xhx9pzhj 3172 2 : : : cord-005646-xhx9pzhj 3172 3 the the DT cord-005646-xhx9pzhj 3172 4 described describe VBN cord-005646-xhx9pzhj 3172 5 patients patient NNS cord-005646-xhx9pzhj 3172 6 developed develop VBD cord-005646-xhx9pzhj 3172 7 severe severe JJ cord-005646-xhx9pzhj 3172 8 ascites ascites NN cord-005646-xhx9pzhj 3172 9 with with IN cord-005646-xhx9pzhj 3172 10 insidious insidious JJ cord-005646-xhx9pzhj 3172 11 renal renal JJ cord-005646-xhx9pzhj 3172 12 dysfunction dysfunction NN cord-005646-xhx9pzhj 3172 13 and and CC cord-005646-xhx9pzhj 3172 14 abnormal abnormal JJ cord-005646-xhx9pzhj 3172 15 sodium sodium NN cord-005646-xhx9pzhj 3172 16 - - HYPH cord-005646-xhx9pzhj 3172 17 water water NN cord-005646-xhx9pzhj 3172 18 handling handling NN cord-005646-xhx9pzhj 3172 19 during during IN cord-005646-xhx9pzhj 3172 20 admission admission NN cord-005646-xhx9pzhj 3172 21 at at IN cord-005646-xhx9pzhj 3172 22 PICU PICU NNP cord-005646-xhx9pzhj 3172 23 and and CC cord-005646-xhx9pzhj 3172 24 fullfilled fullfille VBD cord-005646-xhx9pzhj 3172 25 clinical clinical JJ cord-005646-xhx9pzhj 3172 26 criteria criterion NNS cord-005646-xhx9pzhj 3172 27 fur fur NN cord-005646-xhx9pzhj 3172 28 HRS hrs CD cord-005646-xhx9pzhj 3172 29 . . . cord-005646-xhx9pzhj 3173 1 Treated treat VBN cord-005646-xhx9pzhj 3173 2 according accord VBG cord-005646-xhx9pzhj 3173 3 to to IN cord-005646-xhx9pzhj 3173 4 the the DT cord-005646-xhx9pzhj 3173 5 cited cite VBN cord-005646-xhx9pzhj 3173 6 principles principle NNS cord-005646-xhx9pzhj 3173 7 , , , cord-005646-xhx9pzhj 3173 8 all all DT cord-005646-xhx9pzhj 3173 9 patients patient NNS cord-005646-xhx9pzhj 3173 10 showed show VBD cord-005646-xhx9pzhj 3173 11 improvement improvement NN cord-005646-xhx9pzhj 3173 12 of of IN cord-005646-xhx9pzhj 3173 13 GFR GFR NNP cord-005646-xhx9pzhj 3173 14 , , , cord-005646-xhx9pzhj 3173 15 with with IN cord-005646-xhx9pzhj 3173 16 increased increase VBN cord-005646-xhx9pzhj 3173 17 natriuresis natriuresis JJ cord-005646-xhx9pzhj 3173 18 and and CC cord-005646-xhx9pzhj 3173 19 gradual gradual JJ cord-005646-xhx9pzhj 3173 20 decrease decrease NN cord-005646-xhx9pzhj 3173 21 of of IN cord-005646-xhx9pzhj 3173 22 ascites ascites NN cord-005646-xhx9pzhj 3173 23 . . . cord-005646-xhx9pzhj 3174 1 Eventually eventually RB cord-005646-xhx9pzhj 3174 2 , , , cord-005646-xhx9pzhj 3174 3 renal renal JJ cord-005646-xhx9pzhj 3174 4 function function NN cord-005646-xhx9pzhj 3174 5 normalised normalise VBN cord-005646-xhx9pzhj 3174 6 completly completly RB cord-005646-xhx9pzhj 3174 7 . . . cord-005646-xhx9pzhj 3175 1 Conclusion conclusion NN cord-005646-xhx9pzhj 3175 2 : : : cord-005646-xhx9pzhj 3175 3 ERE ERE NNP cord-005646-xhx9pzhj 3175 4 deserves deserve VBZ cord-005646-xhx9pzhj 3175 5 greater great JJR cord-005646-xhx9pzhj 3175 6 recogmitimn recogmitimn NN cord-005646-xhx9pzhj 3175 7 in in IN cord-005646-xhx9pzhj 3175 8 the the DT cord-005646-xhx9pzhj 3175 9 PICU PICU NNP cord-005646-xhx9pzhj 3175 10 population population NN cord-005646-xhx9pzhj 3175 11 ; ; : cord-005646-xhx9pzhj 3175 12 diagnosis diagnosis NN cord-005646-xhx9pzhj 3175 13 can can MD cord-005646-xhx9pzhj 3175 14 be be VB cord-005646-xhx9pzhj 3175 15 suspected suspect VBN cord-005646-xhx9pzhj 3175 16 on on IN cord-005646-xhx9pzhj 3175 17 clinical clinical JJ cord-005646-xhx9pzhj 3175 18 criteria criterion NNS cord-005646-xhx9pzhj 3175 19 . . . cord-005646-xhx9pzhj 3176 1 With with IN cord-005646-xhx9pzhj 3176 2 this this DT cord-005646-xhx9pzhj 3176 3 increased increase VBN cord-005646-xhx9pzhj 3176 4 awareness awareness NN cord-005646-xhx9pzhj 3176 5 , , , cord-005646-xhx9pzhj 3176 6 therapy therapy NN cord-005646-xhx9pzhj 3176 7 tun tun NN cord-005646-xhx9pzhj 3176 8 be be VB cord-005646-xhx9pzhj 3176 9 instituted institute VBN cord-005646-xhx9pzhj 3176 10 at at IN cord-005646-xhx9pzhj 3176 11 an an DT cord-005646-xhx9pzhj 3176 12 early early JJ cord-005646-xhx9pzhj 3176 13 phase phase NN cord-005646-xhx9pzhj 3176 14 , , , cord-005646-xhx9pzhj 3176 15 with with IN cord-005646-xhx9pzhj 3176 16 better well JJR cord-005646-xhx9pzhj 3176 17 prospects prospect NNS cord-005646-xhx9pzhj 3176 18 for for IN cord-005646-xhx9pzhj 3176 19 recovery recovery NN cord-005646-xhx9pzhj 3176 20 . . . cord-005646-xhx9pzhj 3177 1 Positive positive JJ cord-005646-xhx9pzhj 3177 2 outcome outcome NN cord-005646-xhx9pzhj 3177 3 of of IN cord-005646-xhx9pzhj 3177 4 HEm HEm NNS cord-005646-xhx9pzhj 3177 5 depends depend VBZ cord-005646-xhx9pzhj 3177 6 on on IN cord-005646-xhx9pzhj 3177 7 early early JJ cord-005646-xhx9pzhj 3177 8 recognition recognition NN cord-005646-xhx9pzhj 3177 9 of of IN cord-005646-xhx9pzhj 3177 10 the the DT cord-005646-xhx9pzhj 3177 11 clinical clinical JJ cord-005646-xhx9pzhj 3177 12 picture picture NN cord-005646-xhx9pzhj 3177 13 , , , cord-005646-xhx9pzhj 3177 14 understanding understanding NN cord-005646-xhx9pzhj 3177 15 of of IN cord-005646-xhx9pzhj 3177 16 the the DT cord-005646-xhx9pzhj 3177 17 pathophysiology pathophysiology NN cord-005646-xhx9pzhj 3177 18 , , , cord-005646-xhx9pzhj 3177 19 and and CC cord-005646-xhx9pzhj 3177 20 early early JJ cord-005646-xhx9pzhj 3177 21 institution institution NN cord-005646-xhx9pzhj 3177 22 of of IN cord-005646-xhx9pzhj 3177 23 consistent consistent JJ cord-005646-xhx9pzhj 3177 24 treatment treatment NN cord-005646-xhx9pzhj 3177 25 . . . cord-005646-xhx9pzhj 3178 1 MTX MTX NNP cord-005646-xhx9pzhj 3178 2 is be VBZ cord-005646-xhx9pzhj 3178 3 an an DT cord-005646-xhx9pzhj 3178 4 antimetatxflite antimetatxflite NNP cord-005646-xhx9pzhj 3178 5 widely widely RB cord-005646-xhx9pzhj 3178 6 used use VBN cord-005646-xhx9pzhj 3178 7 as as IN cord-005646-xhx9pzhj 3178 8 chemotherapeutic chemotherapeutic JJ cord-005646-xhx9pzhj 3178 9 agents agent NNS cord-005646-xhx9pzhj 3178 10 . . . cord-005646-xhx9pzhj 3179 1 High high JJ cord-005646-xhx9pzhj 3179 2 dose dose NN cord-005646-xhx9pzhj 3179 3 iVITX iVITX NNP cord-005646-xhx9pzhj 3180 1 ( ( -LRB- cord-005646-xhx9pzhj 3180 2 I -PRON- PRP cord-005646-xhx9pzhj 3180 3 to to IN cord-005646-xhx9pzhj 3180 4 30~m2 30~m2 LS cord-005646-xhx9pzhj 3180 5 ) ) -RRB- cord-005646-xhx9pzhj 3181 1 administered administer VBN cord-005646-xhx9pzhj 3181 2 as as IN cord-005646-xhx9pzhj 3181 3 a a DT cord-005646-xhx9pzhj 3181 4 prolonged prolong VBN cord-005646-xhx9pzhj 3181 5 intravenous intravenous JJ cord-005646-xhx9pzhj 3181 6 infusion infusion NN cord-005646-xhx9pzhj 3181 7 ( ( -LRB- cord-005646-xhx9pzhj 3181 8 over over IN cord-005646-xhx9pzhj 3181 9 4 4 CD cord-005646-xhx9pzhj 3181 10 - - SYM cord-005646-xhx9pzhj 3181 11 42 42 CD cord-005646-xhx9pzhj 3181 12 hours hour NNS cord-005646-xhx9pzhj 3181 13 ) ) -RRB- cord-005646-xhx9pzhj 3181 14 , , , cord-005646-xhx9pzhj 3181 15 is be VBZ cord-005646-xhx9pzhj 3181 16 often often RB cord-005646-xhx9pzhj 3181 17 used use VBN cord-005646-xhx9pzhj 3181 18 to to TO cord-005646-xhx9pzhj 3181 19 treat treat VB cord-005646-xhx9pzhj 3181 20 malignant malignant JJ cord-005646-xhx9pzhj 3181 21 paediatric paediatric JJ cord-005646-xhx9pzhj 3181 22 diseases disease NNS cord-005646-xhx9pzhj 3181 23 . . . cord-005646-xhx9pzhj 3182 1 Major major JJ cord-005646-xhx9pzhj 3182 2 complications complication NNS cord-005646-xhx9pzhj 3182 3 of of IN cord-005646-xhx9pzhj 3182 4 this this DT cord-005646-xhx9pzhj 3182 5 treatment treatment NN cord-005646-xhx9pzhj 3182 6 are be VBP cord-005646-xhx9pzhj 3182 7 myelosuppression myelosuppression NNP cord-005646-xhx9pzhj 3182 8 , , , cord-005646-xhx9pzhj 3182 9 orointestinal orointestinal NNP cord-005646-xhx9pzhj 3182 10 mucositis mucositis NNP cord-005646-xhx9pzhj 3182 11 , , , cord-005646-xhx9pzhj 3182 12 dermatitis dermatitis NN cord-005646-xhx9pzhj 3182 13 and and CC cord-005646-xhx9pzhj 3182 14 impairment impairment NN cord-005646-xhx9pzhj 3182 15 of of IN cord-005646-xhx9pzhj 3182 16 anal anal JJ cord-005646-xhx9pzhj 3182 17 function function NN cord-005646-xhx9pzhj 3182 18 . . . cord-005646-xhx9pzhj 3183 1 We -PRON- PRP cord-005646-xhx9pzhj 3183 2 report report VBP cord-005646-xhx9pzhj 3183 3 two two CD cord-005646-xhx9pzhj 3183 4 cases case NNS cord-005646-xhx9pzhj 3183 5 of of IN cord-005646-xhx9pzhj 3183 6 MTX MTX NNP cord-005646-xhx9pzhj 3183 7 overd overd NNS cord-005646-xhx9pzhj 3183 8 ~ ~ NFP cord-005646-xhx9pzhj 3183 9 age age NN cord-005646-xhx9pzhj 3183 10 occurred occur VBD cord-005646-xhx9pzhj 3183 11 in in IN cord-005646-xhx9pzhj 3183 12 two two CD cord-005646-xhx9pzhj 3183 13 children child NNS cord-005646-xhx9pzhj 3183 14 ( ( -LRB- cord-005646-xhx9pzhj 3183 15 5-year 5-year CD cord-005646-xhx9pzhj 3183 16 - - HYPH cord-005646-xhx9pzhj 3183 17 old old JJ cord-005646-xhx9pzhj 3183 18 . . . cord-005646-xhx9pzhj 3184 1 14 14 CD cord-005646-xhx9pzhj 3184 2 month month NN cord-005646-xhx9pzhj 3184 3 - - HYPH cord-005646-xhx9pzhj 3184 4 old old JJ cord-005646-xhx9pzhj 3184 5 ) ) -RRB- cord-005646-xhx9pzhj 3184 6 t t NN cord-005646-xhx9pzhj 3184 7 ~ ~ CD cord-005646-xhx9pzhj 3184 8 ted ted NNP cord-005646-xhx9pzhj 3184 9 for for IN cord-005646-xhx9pzhj 3184 10 acute acute JJ cord-005646-xhx9pzhj 3184 11 lymphoblastic lymphoblastic JJ cord-005646-xhx9pzhj 3184 12 leukaemia leukaemia NN cord-005646-xhx9pzhj 3184 13 . . . cord-005646-xhx9pzhj 3185 1 They -PRON- PRP cord-005646-xhx9pzhj 3185 2 were be VBD cord-005646-xhx9pzhj 3185 3 treated treat VBN cord-005646-xhx9pzhj 3185 4 by by IN cord-005646-xhx9pzhj 3185 5 CAVH CAVH NNP cord-005646-xhx9pzhj 3185 6 and and CC cord-005646-xhx9pzhj 3185 7 the the DT cord-005646-xhx9pzhj 3185 8 MTX MTX NNP cord-005646-xhx9pzhj 3185 9 bhK bhK NNP cord-005646-xhx9pzhj 3186 1 ~d ~d JJ cord-005646-xhx9pzhj 3186 2 levels level NNS cord-005646-xhx9pzhj 3186 3 rapidly rapidly RB cord-005646-xhx9pzhj 3186 4 decreasedavoiding decreasedavoide VBG cord-005646-xhx9pzhj 3186 5 multisystemic multisystemic JJ cord-005646-xhx9pzhj 3186 6 involvement involvement NN cord-005646-xhx9pzhj 3186 7 . . . cord-005646-xhx9pzhj 3187 1 Establishment establishment NN cord-005646-xhx9pzhj 3187 2 of of IN cord-005646-xhx9pzhj 3187 3 alkaline alkaline JJ cord-005646-xhx9pzhj 3187 4 diuresis diuresis NN cord-005646-xhx9pzhj 3187 5 and and CC cord-005646-xhx9pzhj 3187 6 monitoring monitoring NN cord-005646-xhx9pzhj 3187 7 of of IN cord-005646-xhx9pzhj 3187 8 plasma plasma NN cord-005646-xhx9pzhj 3187 9 MTX mtx NN cord-005646-xhx9pzhj 3187 10 levels level NNS cord-005646-xhx9pzhj 3187 11 during during IN cord-005646-xhx9pzhj 3187 12 treatment treatment NN cord-005646-xhx9pzhj 3187 13 is be VBZ cord-005646-xhx9pzhj 3187 14 essential essential JJ cord-005646-xhx9pzhj 3187 15 to to TO cord-005646-xhx9pzhj 3187 16 prevent prevent VB cord-005646-xhx9pzhj 3187 17 nephrotoxicity nephrotoxicity NN cord-005646-xhx9pzhj 3187 18 . . . cord-005646-xhx9pzhj 3188 1 However however RB cord-005646-xhx9pzhj 3188 2 . . . cord-005646-xhx9pzhj 3189 1 leuco',cnn leuco',cnn JJ cord-005646-xhx9pzhj 3189 2 rescue rescue NN cord-005646-xhx9pzhj 3189 3 may may MD cord-005646-xhx9pzhj 3189 4 not not RB cord-005646-xhx9pzhj 3189 5 prevent prevent VB cord-005646-xhx9pzhj 3189 6 the the DT cord-005646-xhx9pzhj 3189 7 development development NN cord-005646-xhx9pzhj 3189 8 of of IN cord-005646-xhx9pzhj 3189 9 potentially potentially RB cord-005646-xhx9pzhj 3189 10 lethal lethal JJ cord-005646-xhx9pzhj 3189 11 toxicities toxicity NNS cord-005646-xhx9pzhj 3189 12 in in IN cord-005646-xhx9pzhj 3189 13 patients patient NNS cord-005646-xhx9pzhj 3189 14 with with IN cord-005646-xhx9pzhj 3189 15 MTX MTX NNP cord-005646-xhx9pzhj 3189 16 concentrations concentration NNS cord-005646-xhx9pzhj 3189 17 persistantl persistantl JJ cord-005646-xhx9pzhj 3189 18 } } -RRB- cord-005646-xhx9pzhj 3189 19 exceeding exceed VBG cord-005646-xhx9pzhj 3189 20 t0mM. t0mM. NNP cord-005646-xhx9pzhj 3190 1 In in IN cord-005646-xhx9pzhj 3190 2 these these DT cord-005646-xhx9pzhj 3190 3 s s NNS cord-005646-xhx9pzhj 3190 4 cases case NNS cord-005646-xhx9pzhj 3190 5 , , , cord-005646-xhx9pzhj 3190 6 em'ly em'ly NN cord-005646-xhx9pzhj 3190 7 treatment treatment NN cord-005646-xhx9pzhj 3190 8 of of IN cord-005646-xhx9pzhj 3190 9 MTX MTX NNP cord-005646-xhx9pzhj 3190 10 intoxication intoxication NN cord-005646-xhx9pzhj 3190 11 may may MD cord-005646-xhx9pzhj 3190 12 pm pm VB cord-005646-xhx9pzhj 3190 13 ~ ~ NFP cord-005646-xhx9pzhj 3190 14 cnt cnt NNP cord-005646-xhx9pzhj 3190 15 myelosuppression myelosuppression NNP cord-005646-xhx9pzhj 3190 16 and and CC cord-005646-xhx9pzhj 3190 17 reducerenal reducerenal JJ cord-005646-xhx9pzhj 3190 18 damage damage NN cord-005646-xhx9pzhj 3190 19 . . . cord-005646-xhx9pzhj 3191 1 The the DT cord-005646-xhx9pzhj 3191 2 goal goal NN cord-005646-xhx9pzhj 3191 3 is be VBZ cord-005646-xhx9pzhj 3191 4 to to TO cord-005646-xhx9pzhj 3191 5 lower lower VB cord-005646-xhx9pzhj 3191 6 the the DT cord-005646-xhx9pzhj 3191 7 concentration concentration NN cord-005646-xhx9pzhj 3191 8 to to IN cord-005646-xhx9pzhj 3191 9 below below IN cord-005646-xhx9pzhj 3191 10 10 10 CD cord-005646-xhx9pzhj 3191 11 mmoLL mmoll NN cord-005646-xhx9pzhj 3191 12 , , , cord-005646-xhx9pzhj 3191 13 at at IN cord-005646-xhx9pzhj 3191 14 which which WDT cord-005646-xhx9pzhj 3191 15 time time NN cord-005646-xhx9pzhj 3191 16 rescue rescue NN cord-005646-xhx9pzhj 3191 17 agents agent NNS cord-005646-xhx9pzhj 3191 18 aleme aleme NNP cord-005646-xhx9pzhj 3191 19 would would MD cord-005646-xhx9pzhj 3191 20 be be VB cord-005646-xhx9pzhj 3191 21 expected expect VBN cord-005646-xhx9pzhj 3191 22 to to TO cord-005646-xhx9pzhj 3191 23 be be VB cord-005646-xhx9pzhj 3191 24 cllcctive cllcctive JJ cord-005646-xhx9pzhj 3191 25 . . . cord-005646-xhx9pzhj 3192 1 Respective respective JJ cord-005646-xhx9pzhj 3192 2 indications indication NNS cord-005646-xhx9pzhj 3192 3 of of IN cord-005646-xhx9pzhj 3192 4 these these DT cord-005646-xhx9pzhj 3192 5 remo',at remo',at JJ cord-005646-xhx9pzhj 3192 6 mctNy.:is mctNy.:is NNP cord-005646-xhx9pzhj 3192 7 are be VBP cord-005646-xhx9pzhj 3192 8 still still RB cord-005646-xhx9pzhj 3192 9 discussed discuss VBN cord-005646-xhx9pzhj 3192 10 : : : cord-005646-xhx9pzhj 3193 1 Hacmt Hacmt NNP cord-005646-xhx9pzhj 3194 1 ~ialysis ~ialysis NFP cord-005646-xhx9pzhj 3195 1 t~ t~ ADD cord-005646-xhx9pzhj 3196 1 eharc(~l eharc(~l DT cord-005646-xhx9pzhj 3196 2 haemoperfusion haemoperfusion NN cord-005646-xhx9pzhj 3196 3 should should MD cord-005646-xhx9pzhj 3196 4 be be VB cord-005646-xhx9pzhj 3196 5 prolx',sed prolx',se VBN cord-005646-xhx9pzhj 3196 6 for for IN cord-005646-xhx9pzhj 3196 7 massive massive JJ cord-005646-xhx9pzhj 3196 8 and and CC cord-005646-xhx9pzhj 3196 9 acute acute JJ cord-005646-xhx9pzhj 3196 10 intoxication intoxication NN cord-005646-xhx9pzhj 3196 11 . . . cord-005646-xhx9pzhj 3197 1 However however RB cord-005646-xhx9pzhj 3197 2 , , , cord-005646-xhx9pzhj 3197 3 rebound rebound NN cord-005646-xhx9pzhj 3197 4 has have VBZ cord-005646-xhx9pzhj 3197 5 been be VBN cord-005646-xhx9pzhj 3197 6 reported report VBN cord-005646-xhx9pzhj 3197 7 after after IN cord-005646-xhx9pzhj 3197 8 combined combine VBN cord-005646-xhx9pzhj 3197 9 hcmodialysis hcmodialysis NN cord-005646-xhx9pzhj 3197 10 and and CC cord-005646-xhx9pzhj 3197 11 hemoperfusion hemoperfusion NN cord-005646-xhx9pzhj 3197 12 . . . cord-005646-xhx9pzhj 3198 1 Exchange exchange NN cord-005646-xhx9pzhj 3198 2 transfusion transfusion NN cord-005646-xhx9pzhj 3198 3 may may MD cord-005646-xhx9pzhj 3198 4 be be VB cord-005646-xhx9pzhj 3198 5 proposed propose VBN cord-005646-xhx9pzhj 3198 6 as as IN cord-005646-xhx9pzhj 3198 7 a a DT cord-005646-xhx9pzhj 3198 8 treatment treatment NN cord-005646-xhx9pzhj 3198 9 for for IN cord-005646-xhx9pzhj 3198 10 prolonged prolonged JJ cord-005646-xhx9pzhj 3198 11 and and CC cord-005646-xhx9pzhj 3198 12 moderate moderate JJ cord-005646-xhx9pzhj 3198 13 intoxication intoxication NN cord-005646-xhx9pzhj 3198 14 . . . cord-005646-xhx9pzhj 3199 1 Peritoneal peritoneal JJ cord-005646-xhx9pzhj 3199 2 dialysis dialysis NN cord-005646-xhx9pzhj 3199 3 is be VBZ cord-005646-xhx9pzhj 3199 4 an an DT cord-005646-xhx9pzhj 3199 5 incflbedve incflbedve JJ cord-005646-xhx9pzhj 3199 6 method method NN cord-005646-xhx9pzhj 3199 7 for for IN cord-005646-xhx9pzhj 3199 8 remo~ remo~ NNP cord-005646-xhx9pzhj 3199 9 al al NNP cord-005646-xhx9pzhj 3199 10 of of IN cord-005646-xhx9pzhj 3199 11 MTX MTX NNP cord-005646-xhx9pzhj 3199 12 . . . cord-005646-xhx9pzhj 3200 1 CAVH CAVH NNP cord-005646-xhx9pzhj 3200 2 was be VBD cord-005646-xhx9pzhj 3200 3 used use VBN cord-005646-xhx9pzhj 3200 4 in in IN cord-005646-xhx9pzhj 3200 5 our -PRON- PRP$ cord-005646-xhx9pzhj 3200 6 ICU ICU NNP cord-005646-xhx9pzhj 3200 7 . . . cord-005646-xhx9pzhj 3201 1 CAVH CAVH NNP cord-005646-xhx9pzhj 3201 2 is be VBZ cord-005646-xhx9pzhj 3201 3 a a DT cord-005646-xhx9pzhj 3201 4 simple simple JJ cord-005646-xhx9pzhj 3201 5 method method NN cord-005646-xhx9pzhj 3201 6 for for IN cord-005646-xhx9pzhj 3201 7 blood blood NN cord-005646-xhx9pzhj 3201 8 purification purification NN cord-005646-xhx9pzhj 3201 9 and and CC cord-005646-xhx9pzhj 3201 10 N':dy N':dy NNP cord-005646-xhx9pzhj 3201 11 iluid iluid JJ cord-005646-xhx9pzhj 3201 12 control control NN cord-005646-xhx9pzhj 3201 13 . . . cord-005646-xhx9pzhj 3202 1 Use Use NNP cord-005646-xhx9pzhj 3202 2 of of IN cord-005646-xhx9pzhj 3202 3 CAVH CAVH NNP cord-005646-xhx9pzhj 3202 4 was be VBD cord-005646-xhx9pzhj 3202 5 never never RB cord-005646-xhx9pzhj 3202 6 be be VB cord-005646-xhx9pzhj 3202 7 reported report VBN cord-005646-xhx9pzhj 3202 8 in in IN cord-005646-xhx9pzhj 3202 9 this this DT cord-005646-xhx9pzhj 3202 10 indication indication NN cord-005646-xhx9pzhj 3202 11 to to IN cord-005646-xhx9pzhj 3202 12 our -PRON- PRP$ cord-005646-xhx9pzhj 3202 13 knowledge knowledge NN cord-005646-xhx9pzhj 3202 14 . . . cord-005646-xhx9pzhj 3203 1 Simplicity simplicity NN cord-005646-xhx9pzhj 3203 2 , , , cord-005646-xhx9pzhj 3203 3 rap rap NN cord-005646-xhx9pzhj 3203 4 ~ ~ NN cord-005646-xhx9pzhj 3203 5 d d NN cord-005646-xhx9pzhj 3203 6 application application NN cord-005646-xhx9pzhj 3203 7 and and CC cord-005646-xhx9pzhj 3203 8 gco.l gco.l CD cord-005646-xhx9pzhj 3203 9 clinical clinical JJ cord-005646-xhx9pzhj 3203 10 tolerance tolerance NN cord-005646-xhx9pzhj 3203 11 are be VBP cord-005646-xhx9pzhj 3203 12 the the DT cord-005646-xhx9pzhj 3203 13 main main JJ cord-005646-xhx9pzhj 3203 14 advantages advantage NNS cord-005646-xhx9pzhj 3203 15 of of IN cord-005646-xhx9pzhj 3203 16 this this DT cord-005646-xhx9pzhj 3203 17 technique technique NN cord-005646-xhx9pzhj 3203 18 . . . cord-005646-xhx9pzhj 3204 1 The the DT cord-005646-xhx9pzhj 3204 2 technique technique NN cord-005646-xhx9pzhj 3204 3 presents present VBZ cord-005646-xhx9pzhj 3204 4 ~peclal ~peclal CD cord-005646-xhx9pzhj 3204 5 advantages advantage NNS cord-005646-xhx9pzhj 3204 6 in in IN cord-005646-xhx9pzhj 3204 7 terms term NNS cord-005646-xhx9pzhj 3204 8 of of IN cord-005646-xhx9pzhj 3204 9 low low JJ cord-005646-xhx9pzhj 3204 10 priming priming NN cord-005646-xhx9pzhj 3204 11 volume volume NN cord-005646-xhx9pzhj 3204 12 of of IN cord-005646-xhx9pzhj 3204 13 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 3204 14 circuit circuit NN cord-005646-xhx9pzhj 3204 15 , , , cord-005646-xhx9pzhj 3204 16 low low JJ cord-005646-xhx9pzhj 3204 17 blood blood NN cord-005646-xhx9pzhj 3204 18 flow flow NN cord-005646-xhx9pzhj 3204 19 , , , cord-005646-xhx9pzhj 3204 20 low low JJ cord-005646-xhx9pzhj 3204 21 rate rate NN cord-005646-xhx9pzhj 3204 22 heparinisation heparinisation NN cord-005646-xhx9pzhj 3204 23 . . . cord-005646-xhx9pzhj 3205 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 3205 2 results result NNS cord-005646-xhx9pzhj 3205 3 show show VBP cord-005646-xhx9pzhj 3205 4 a a DT cord-005646-xhx9pzhj 3205 5 decreaseof decreaseof NNP cord-005646-xhx9pzhj 3205 6 plasma plasma NN cord-005646-xhx9pzhj 3205 7 MTX MTX NNP cord-005646-xhx9pzhj 3205 8 concentration concentration NN cord-005646-xhx9pzhj 3205 9 and and CC cord-005646-xhx9pzhj 3205 10 a a DT cord-005646-xhx9pzhj 3205 11 rapid rapid JJ cord-005646-xhx9pzhj 3205 12 reduction reduction NN cord-005646-xhx9pzhj 3205 13 of of IN cord-005646-xhx9pzhj 3205 14 halfqite halfqite NN cord-005646-xhx9pzhj 3205 15 of of IN cord-005646-xhx9pzhj 3205 16 elimination elimination NN cord-005646-xhx9pzhj 3205 17 ( ( -LRB- cord-005646-xhx9pzhj 3205 18 t5 t5 NNP cord-005646-xhx9pzhj 3205 19 hours hour NNS cord-005646-xhx9pzhj 3205 20 over over IN cord-005646-xhx9pzhj 3205 21 the the DT cord-005646-xhx9pzhj 3205 22 period period NN cord-005646-xhx9pzhj 3205 23 of of IN cord-005646-xhx9pzhj 3205 24 CAVH CAVH NNP cord-005646-xhx9pzhj 3205 25 ) ) -RRB- cord-005646-xhx9pzhj 3205 26 . . . cord-005646-xhx9pzhj 3206 1 Moreover moreover RB cord-005646-xhx9pzhj 3206 2 , , , cord-005646-xhx9pzhj 3206 3 we -PRON- PRP cord-005646-xhx9pzhj 3206 4 did do VBD cord-005646-xhx9pzhj 3206 5 n't not RB cord-005646-xhx9pzhj 3206 6 delec~ delec~ VB cord-005646-xhx9pzhj 3207 1 d d NN cord-005646-xhx9pzhj 3207 2 rebound rebound NN cord-005646-xhx9pzhj 3207 3 after after IN cord-005646-xhx9pzhj 3207 4 stopping stop VBG cord-005646-xhx9pzhj 3207 5 prc prc NNP cord-005646-xhx9pzhj 3207 6 , , , cord-005646-xhx9pzhj 3207 7 xedure xedure NNP cord-005646-xhx9pzhj 3207 8 . . . cord-005646-xhx9pzhj 3208 1 Small small JJ cord-005646-xhx9pzhj 3208 2 size size NN cord-005646-xhx9pzhj 3208 3 of of IN cord-005646-xhx9pzhj 3208 4 the the DT cord-005646-xhx9pzhj 3208 5 I i NN cord-005646-xhx9pzhj 3208 6 : : : cord-005646-xhx9pzhj 3208 7 ratients ratient NNS cord-005646-xhx9pzhj 3208 8 may may MD cord-005646-xhx9pzhj 3208 9 present present VB cord-005646-xhx9pzhj 3208 10 sometime sometime RB cord-005646-xhx9pzhj 3208 11 special special JJ cord-005646-xhx9pzhj 3208 12 problems problem NNS cord-005646-xhx9pzhj 3208 13 , , , cord-005646-xhx9pzhj 3208 14 but but CC cord-005646-xhx9pzhj 3208 15 these these DT cord-005646-xhx9pzhj 3208 16 technical technical JJ cord-005646-xhx9pzhj 3208 17 problems problem NNS cord-005646-xhx9pzhj 3208 18 can can MD cord-005646-xhx9pzhj 3208 19 be be VB cord-005646-xhx9pzhj 3208 20 overcome overcome VBN cord-005646-xhx9pzhj 3208 21 , , , cord-005646-xhx9pzhj 3208 22 No no DT cord-005646-xhx9pzhj 3208 23 severe severe JJ cord-005646-xhx9pzhj 3208 24 complication complication NN cord-005646-xhx9pzhj 3208 25 ( ( -LRB- cord-005646-xhx9pzhj 3208 26 Needing need VBG cord-005646-xhx9pzhj 3208 27 , , , cord-005646-xhx9pzhj 3208 28 inlection inlection NN cord-005646-xhx9pzhj 3208 29 ) ) -RRB- cord-005646-xhx9pzhj 3208 30 were be VBD cord-005646-xhx9pzhj 3208 31 observed observe VBN cord-005646-xhx9pzhj 3208 32 during during IN cord-005646-xhx9pzhj 3208 33 filtration filtration NN cord-005646-xhx9pzhj 3208 34 , , , cord-005646-xhx9pzhj 3209 1 In in IN cord-005646-xhx9pzhj 3209 2 summary summary NN cord-005646-xhx9pzhj 3209 3 , , , cord-005646-xhx9pzhj 3209 4 aggressive aggressive JJ cord-005646-xhx9pzhj 3209 5 intravenous intravenous JJ cord-005646-xhx9pzhj 3209 6 fluid fluid JJ cord-005646-xhx9pzhj 3209 7 hydration hydration NN cord-005646-xhx9pzhj 3209 8 and and CC cord-005646-xhx9pzhj 3209 9 alkaliniaation alkaliniaation NN cord-005646-xhx9pzhj 3209 10 of of IN cord-005646-xhx9pzhj 3209 11 the the DT cord-005646-xhx9pzhj 3209 12 urine urine NN cord-005646-xhx9pzhj 3209 13 coupled couple VBN cord-005646-xhx9pzhj 3209 14 with with IN cord-005646-xhx9pzhj 3209 15 careful careful JJ cord-005646-xhx9pzhj 3209 16 monitoring monitoring NN cord-005646-xhx9pzhj 3209 17 of of IN cord-005646-xhx9pzhj 3209 18 renal renal JJ cord-005646-xhx9pzhj 3209 19 function function NN cord-005646-xhx9pzhj 3209 20 and and CC cord-005646-xhx9pzhj 3209 21 plasma plasma NN cord-005646-xhx9pzhj 3209 22 MTX MTX NNP cord-005646-xhx9pzhj 3209 23 concentrations concentration NNS cord-005646-xhx9pzhj 3209 24 during during IN cord-005646-xhx9pzhj 3209 25 and and CC cord-005646-xhx9pzhj 3209 26 al'tcr al'tcr NN cord-005646-xhx9pzhj 3209 27 infusion infusion NN cord-005646-xhx9pzhj 3209 28 along along IN cord-005646-xhx9pzhj 3209 29 with with IN cord-005646-xhx9pzhj 3209 30 lem lem NNP cord-005646-xhx9pzhj 3209 31 ~ ~ NFP cord-005646-xhx9pzhj 3209 32 overin overin NNP cord-005646-xhx9pzhj 3209 33 rescue rescue NNP cord-005646-xhx9pzhj 3209 34 has have VBZ cord-005646-xhx9pzhj 3209 35 reduced reduce VBN cord-005646-xhx9pzhj 3209 36 the the DT cord-005646-xhx9pzhj 3209 37 inNdcace inNdcace NNP cord-005646-xhx9pzhj 3209 38 of of IN cord-005646-xhx9pzhj 3209 39 life life NN cord-005646-xhx9pzhj 3209 40 - - HYPH cord-005646-xhx9pzhj 3209 41 threatening threaten VBG cord-005646-xhx9pzhj 3209 42 toxicity toxicity NN cord-005646-xhx9pzhj 3209 43 after after IN cord-005646-xhx9pzhj 3209 44 highdose highdose NN cord-005646-xhx9pzhj 3209 45 MTX MTX NNP cord-005646-xhx9pzhj 3209 46 . . . cord-005646-xhx9pzhj 3210 1 However however RB cord-005646-xhx9pzhj 3210 2 , , , cord-005646-xhx9pzhj 3210 3 some some DT cord-005646-xhx9pzhj 3210 4 MTX MTX NNP cord-005646-xhx9pzhj 3210 5 inu inu NNP cord-005646-xhx9pzhj 3210 6 > > XX cord-005646-xhx9pzhj 3210 7 xication xication NNP cord-005646-xhx9pzhj 3210 8 still still RB cord-005646-xhx9pzhj 3210 9 occurred occur VBD cord-005646-xhx9pzhj 3210 10 , , , cord-005646-xhx9pzhj 3210 11 leading lead VBG cord-005646-xhx9pzhj 3210 12 to to IN cord-005646-xhx9pzhj 3210 13 se se NNP cord-005646-xhx9pzhj 3210 14 ~ ~ NFP cord-005646-xhx9pzhj 3210 15 em em IN cord-005646-xhx9pzhj 3210 16 toxicity toxicity NN cord-005646-xhx9pzhj 3210 17 , , , cord-005646-xhx9pzhj 3210 18 particularly particularly RB cord-005646-xhx9pzhj 3210 19 nephrotoxicity nephrotoxicity NNP cord-005646-xhx9pzhj 3210 20 . . . cord-005646-xhx9pzhj 3211 1 In in IN cord-005646-xhx9pzhj 3211 2 these these DT cord-005646-xhx9pzhj 3211 3 cases case NNS cord-005646-xhx9pzhj 3211 4 , , , cord-005646-xhx9pzhj 3211 5 we -PRON- PRP cord-005646-xhx9pzhj 3211 6 think think VBP cord-005646-xhx9pzhj 3211 7 that that IN cord-005646-xhx9pzhj 3211 8 CAVH CAVH NNP cord-005646-xhx9pzhj 3211 9 ( ( -LRB- cord-005646-xhx9pzhj 3211 10 or or CC cord-005646-xhx9pzhj 3211 11 CAVHD CAVHD NNP cord-005646-xhx9pzhj 3211 12 ) ) -RRB- cord-005646-xhx9pzhj 3211 13 is be VBZ cord-005646-xhx9pzhj 3211 14 a a DT cord-005646-xhx9pzhj 3211 15 reliable reliable JJ cord-005646-xhx9pzhj 3211 16 , , , cord-005646-xhx9pzhj 3211 17 rapid rapid JJ cord-005646-xhx9pzhj 3211 18 method method NN cord-005646-xhx9pzhj 3211 19 without without IN cord-005646-xhx9pzhj 3211 20 rcIx rcix NN cord-005646-xhx9pzhj 3211 21 ~ ~ NFP cord-005646-xhx9pzhj 3211 22 und und CC cord-005646-xhx9pzhj 3211 23 increase increase NN cord-005646-xhx9pzhj 3211 24 in in IN cord-005646-xhx9pzhj 3211 25 plasma plasma NN cord-005646-xhx9pzhj 3211 26 MTX mtx NN cord-005646-xhx9pzhj 3211 27 concentration concentration NN cord-005646-xhx9pzhj 3211 28 or or CC cord-005646-xhx9pzhj 3211 29 important important JJ cord-005646-xhx9pzhj 3211 30 adverses adverse NNS cord-005646-xhx9pzhj 3211 31 effects effect NNS cord-005646-xhx9pzhj 3211 32 compared compare VBN cord-005646-xhx9pzhj 3211 33 to to IN cord-005646-xhx9pzhj 3211 34 other other JJ cord-005646-xhx9pzhj 3211 35 procedure procedure NN cord-005646-xhx9pzhj 3211 36 removal removal NN cord-005646-xhx9pzhj 3211 37 . . . cord-005646-xhx9pzhj 3212 1 Gouyon Gouyon NNP cord-005646-xhx9pzhj 3212 2 JB JB NNP cord-005646-xhx9pzhj 3212 3 , , , cord-005646-xhx9pzhj 3212 4 Germain Germain NNP cord-005646-xhx9pzhj 3212 5 JF JF NNP cord-005646-xhx9pzhj 3212 6 , , , cord-005646-xhx9pzhj 3212 7 Semama Semama NNP cord-005646-xhx9pzhj 3212 8 D D NNP cord-005646-xhx9pzhj 3212 9 , , , cord-005646-xhx9pzhj 3212 10 Pr6vot Pr6vot NNP cord-005646-xhx9pzhj 3212 11 A A NNP cord-005646-xhx9pzhj 3212 12 , , , cord-005646-xhx9pzhj 3212 13 Desgres Desgres NNP cord-005646-xhx9pzhj 3212 14 J J NNP cord-005646-xhx9pzhj 3212 15 Preliminary Preliminary NNP cord-005646-xhx9pzhj 3212 16 limited limited JJ cord-005646-xhx9pzhj 3212 17 data datum NNS cord-005646-xhx9pzhj 3212 18 suggested suggest VBD cord-005646-xhx9pzhj 3212 19 that that IN cord-005646-xhx9pzhj 3212 20 hemofiltration hemofiltration NN cord-005646-xhx9pzhj 3212 21 and and CC cord-005646-xhx9pzhj 3212 22 hemodiafiltration hemodiafiltration NN cord-005646-xhx9pzhj 3212 23 may may MD cord-005646-xhx9pzhj 3212 24 be be VB cord-005646-xhx9pzhj 3212 25 valuable valuable JJ cord-005646-xhx9pzhj 3212 26 in in IN cord-005646-xhx9pzhj 3212 27 some some DT cord-005646-xhx9pzhj 3212 28 neonates neonate NNS cord-005646-xhx9pzhj 3212 29 with with IN cord-005646-xhx9pzhj 3212 30 decompensation decompensation NN cord-005646-xhx9pzhj 3212 31 of of IN cord-005646-xhx9pzhj 3212 32 maple maple NN cord-005646-xhx9pzhj 3212 33 syrup syrup NN cord-005646-xhx9pzhj 3212 34 urine urine NN cord-005646-xhx9pzhj 3212 35 disease disease NN cord-005646-xhx9pzhj 3212 36 ( ( -LRB- cord-005646-xhx9pzhj 3212 37 MSUD MSUD NNP cord-005646-xhx9pzhj 3212 38 ) ) -RRB- cord-005646-xhx9pzhj 3212 39 . . . cord-005646-xhx9pzhj 3213 1 Venovenous Venovenous NNP cord-005646-xhx9pzhj 3213 2 hemofiltration hemofiltration NN cord-005646-xhx9pzhj 3213 3 ( ( -LRB- cord-005646-xhx9pzhj 3213 4 VVHF VVHF NNP cord-005646-xhx9pzhj 3213 5 ) ) -RRB- cord-005646-xhx9pzhj 3213 6 and and CC cord-005646-xhx9pzhj 3213 7 hemodiafiltration hemodiafiltration NN cord-005646-xhx9pzhj 3213 8 ( ( -LRB- cord-005646-xhx9pzhj 3213 9 VVHDF VVHDF NNP cord-005646-xhx9pzhj 3213 10 ) ) -RRB- cord-005646-xhx9pzhj 3213 11 were be VBD cord-005646-xhx9pzhj 3213 12 performed perform VBN cord-005646-xhx9pzhj 3213 13 with with IN cord-005646-xhx9pzhj 3213 14 a a DT cord-005646-xhx9pzhj 3213 15 new new JJ cord-005646-xhx9pzhj 3213 16 neonatal neonatal JJ cord-005646-xhx9pzhj 3213 17 hemo(dia)filter hemo(dia)filter NN cord-005646-xhx9pzhj 3213 18 ( ( -LRB- cord-005646-xhx9pzhj 3213 19 Miniflow Miniflow NNP cord-005646-xhx9pzhj 3213 20 10 10 CD cord-005646-xhx9pzhj 3213 21 , , , cord-005646-xhx9pzhj 3213 22 Hospal Hospal NNP cord-005646-xhx9pzhj 3213 23 ) ) -RRB- cord-005646-xhx9pzhj 3213 24 on on IN cord-005646-xhx9pzhj 3213 25 8 8 CD cord-005646-xhx9pzhj 3213 26 anesthetized anesthetized JJ cord-005646-xhx9pzhj 3213 27 rabbits rabbit NNS cord-005646-xhx9pzhj 3213 28 infused infuse VBN cord-005646-xhx9pzhj 3213 29 with with IN cord-005646-xhx9pzhj 3213 30 branched branch VBN cord-005646-xhx9pzhj 3213 31 - - HYPH cord-005646-xhx9pzhj 3213 32 chain chain NN cord-005646-xhx9pzhj 3213 33 amino amino NN cord-005646-xhx9pzhj 3213 34 acids acid NNS cord-005646-xhx9pzhj 3213 35 ( ( -LRB- cord-005646-xhx9pzhj 3213 36 leucine leucine NN cord-005646-xhx9pzhj 3213 37 , , , cord-005646-xhx9pzhj 3213 38 isoleucine isoleucine NN cord-005646-xhx9pzhj 3213 39 and and CC cord-005646-xhx9pzhj 3213 40 valine valine NN cord-005646-xhx9pzhj 3213 41 ) ) -RRB- cord-005646-xhx9pzhj 3213 42 and and CC cord-005646-xhx9pzhj 3213 43 c~-keto c~-keto NN cord-005646-xhx9pzhj 3213 44 - - HYPH cord-005646-xhx9pzhj 3213 45 isocaproate isocaproate JJ cord-005646-xhx9pzhj 3213 46 . . . cord-005646-xhx9pzhj 3214 1 The the DT cord-005646-xhx9pzhj 3214 2 BCAA BCAA NNP cord-005646-xhx9pzhj 3214 3 and and CC cord-005646-xhx9pzhj 3214 4 aketo aketo NN cord-005646-xhx9pzhj 3214 5 - - HYPH cord-005646-xhx9pzhj 3214 6 isocaproate isocaproate VBG cord-005646-xhx9pzhj 3214 7 blood blood NN cord-005646-xhx9pzhj 3214 8 levels level NNS cord-005646-xhx9pzhj 3214 9 were be VBD cord-005646-xhx9pzhj 3214 10 close close JJ cord-005646-xhx9pzhj 3214 11 to to IN cord-005646-xhx9pzhj 3214 12 those those DT cord-005646-xhx9pzhj 3214 13 previously previously RB cord-005646-xhx9pzhj 3214 14 observed observe VBN cord-005646-xhx9pzhj 3214 15 in in IN cord-005646-xhx9pzhj 3214 16 neonates neonate NNS cord-005646-xhx9pzhj 3214 17 with with IN cord-005646-xhx9pzhj 3214 18 MSUD MSUD NNP cord-005646-xhx9pzhj 3214 19 when when WRB cord-005646-xhx9pzhj 3214 20 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 3214 21 blood blood NN cord-005646-xhx9pzhj 3214 22 purification purification NN cord-005646-xhx9pzhj 3214 23 was be VBD cord-005646-xhx9pzhj 3214 24 required require VBN cord-005646-xhx9pzhj 3214 25 . . . cord-005646-xhx9pzhj 3215 1 VVHF VVHF NNP cord-005646-xhx9pzhj 3215 2 and and CC cord-005646-xhx9pzhj 3215 3 VVHDF VVHDF NNP cord-005646-xhx9pzhj 3215 4 performances performance NNS cord-005646-xhx9pzhj 3215 5 were be VBD cord-005646-xhx9pzhj 3215 6 assessed assess VBN cord-005646-xhx9pzhj 3215 7 with with IN cord-005646-xhx9pzhj 3215 8 two two CD cord-005646-xhx9pzhj 3215 9 different different JJ cord-005646-xhx9pzhj 3215 10 blood blood NN cord-005646-xhx9pzhj 3215 11 flows flow NNS cord-005646-xhx9pzhj 3215 12 ( ( -LRB- cord-005646-xhx9pzhj 3215 13 Qb Qb NNP cord-005646-xhx9pzhj 3215 14 = = SYM cord-005646-xhx9pzhj 3215 15 8.3 8.3 CD cord-005646-xhx9pzhj 3215 16 and and CC cord-005646-xhx9pzhj 3215 17 16.6 16.6 CD cord-005646-xhx9pzhj 3215 18 mL ml NN cord-005646-xhx9pzhj 3215 19 / / SYM cord-005646-xhx9pzhj 3215 20 min min NN cord-005646-xhx9pzhj 3215 21 ) ) -RRB- cord-005646-xhx9pzhj 3215 22 . . . cord-005646-xhx9pzhj 3216 1 VVHDF VVHDF NNP cord-005646-xhx9pzhj 3216 2 was be VBD cord-005646-xhx9pzhj 3216 3 performed perform VBN cord-005646-xhx9pzhj 3216 4 with with IN cord-005646-xhx9pzhj 3216 5 4 4 CD cord-005646-xhx9pzhj 3216 6 dialysate dialysate NN cord-005646-xhx9pzhj 3216 7 flow flow NN cord-005646-xhx9pzhj 3216 8 rates rate NNS cord-005646-xhx9pzhj 3216 9 ( ( -LRB- cord-005646-xhx9pzhj 3216 10 Qd qd NN cord-005646-xhx9pzhj 3216 11 = = SYM cord-005646-xhx9pzhj 3216 12 0,5 0,5 CD cord-005646-xhx9pzhj 3216 13 , , , cord-005646-xhx9pzhj 3216 14 1.0 1.0 CD cord-005646-xhx9pzhj 3216 15 , , , cord-005646-xhx9pzhj 3216 16 2.0 2.0 CD cord-005646-xhx9pzhj 3216 17 and and CC cord-005646-xhx9pzhj 3216 18 3.0 3.0 CD cord-005646-xhx9pzhj 3216 19 L L NNP cord-005646-xhx9pzhj 3216 20 / / SYM cord-005646-xhx9pzhj 3216 21 h h NN cord-005646-xhx9pzhj 3216 22 ) ) -RRB- cord-005646-xhx9pzhj 3216 23 . . . cord-005646-xhx9pzhj 3217 1 Thus thus RB cord-005646-xhx9pzhj 3217 2 , , , cord-005646-xhx9pzhj 3217 3 each each DT cord-005646-xhx9pzhj 3217 4 animal animal NN cord-005646-xhx9pzhj 3217 5 was be VBD cord-005646-xhx9pzhj 3217 6 submitted submit VBN cord-005646-xhx9pzhj 3217 7 to to IN cord-005646-xhx9pzhj 3217 8 10 10 CD cord-005646-xhx9pzhj 3217 9 successive successive JJ cord-005646-xhx9pzhj 3217 10 procedures procedure NNS cord-005646-xhx9pzhj 3217 11 . . . cord-005646-xhx9pzhj 3218 1 Within within IN cord-005646-xhx9pzhj 3218 2 each each DT cord-005646-xhx9pzhj 3218 3 studied study VBN cord-005646-xhx9pzhj 3218 4 period period NN cord-005646-xhx9pzhj 3218 5 , , , cord-005646-xhx9pzhj 3218 6 clearances clearance NNS cord-005646-xhx9pzhj 3218 7 of of IN cord-005646-xhx9pzhj 3218 8 the the DT cord-005646-xhx9pzhj 3218 9 3 3 CD cord-005646-xhx9pzhj 3218 10 BCAA BCAA NNP cord-005646-xhx9pzhj 3218 11 were be VBD cord-005646-xhx9pzhj 3218 12 strictly strictly RB cord-005646-xhx9pzhj 3218 13 similar similar JJ cord-005646-xhx9pzhj 3218 14 . . . cord-005646-xhx9pzhj 3219 1 BCAA BCAA NNP cord-005646-xhx9pzhj 3219 2 clearances clearance NNS cord-005646-xhx9pzhj 3219 3 obtained obtain VBN cord-005646-xhx9pzhj 3219 4 by by IN cord-005646-xhx9pzhj 3219 5 VVHF VVHF NNP cord-005646-xhx9pzhj 3219 6 were be VBD cord-005646-xhx9pzhj 3219 7 similar similar JJ cord-005646-xhx9pzhj 3219 8 to to IN cord-005646-xhx9pzhj 3219 9 ultrafiltrate ultrafiltrate JJ cord-005646-xhx9pzhj 3219 10 rates rate NNS cord-005646-xhx9pzhj 3219 11 ( ( -LRB- cord-005646-xhx9pzhj 3219 12 respectively respectively RB cord-005646-xhx9pzhj 3219 13 , , , cord-005646-xhx9pzhj 3219 14 0.78 0.78 CD cord-005646-xhx9pzhj 3219 15 4 4 CD cord-005646-xhx9pzhj 3219 16 - - SYM cord-005646-xhx9pzhj 3219 17 0.14 0.14 CD cord-005646-xhx9pzhj 3219 18 and and CC cord-005646-xhx9pzhj 3219 19 1.79 1.79 CD cord-005646-xhx9pzhj 3219 20 4 4 CD cord-005646-xhx9pzhj 3219 21 - - SYM cord-005646-xhx9pzhj 3219 22 0.28 0.28 CD cord-005646-xhx9pzhj 3219 23 mL ml NN cord-005646-xhx9pzhj 3219 24 / / SYM cord-005646-xhx9pzhj 3219 25 min min NN cord-005646-xhx9pzhj 3219 26 at at IN cord-005646-xhx9pzhj 3219 27 high high JJ cord-005646-xhx9pzhj 3219 28 and and CC cord-005646-xhx9pzhj 3219 29 low low JJ cord-005646-xhx9pzhj 3219 30 Qb Qb NNP cord-005646-xhx9pzhj 3219 31 ; ; : cord-005646-xhx9pzhj 3219 32 p p NN cord-005646-xhx9pzhj 3219 33 < < XX cord-005646-xhx9pzhj 3219 34 0.05 0.05 CD cord-005646-xhx9pzhj 3219 35 ) ) -RRB- cord-005646-xhx9pzhj 3219 36 . . . cord-005646-xhx9pzhj 3220 1 The the DT cord-005646-xhx9pzhj 3220 2 ~x ~x NNP cord-005646-xhx9pzhj 3220 3 - - HYPH cord-005646-xhx9pzhj 3220 4 keto keto NNP cord-005646-xhx9pzhj 3220 5 - - HYPH cord-005646-xhx9pzhj 3220 6 isocaproate isocaproate JJ cord-005646-xhx9pzhj 3220 7 clearances clearance NNS cord-005646-xhx9pzhj 3220 8 obtained obtain VBN cord-005646-xhx9pzhj 3220 9 by by IN cord-005646-xhx9pzhj 3220 10 VVHF VVHF NNP cord-005646-xhx9pzhj 3220 11 were be VBD cord-005646-xhx9pzhj 3220 12 0.39 0.39 CD cord-005646-xhx9pzhj 3220 13 4 4 CD cord-005646-xhx9pzhj 3220 14 - - SYM cord-005646-xhx9pzhj 3220 15 0.17 0.17 CD cord-005646-xhx9pzhj 3220 16 and and CC cord-005646-xhx9pzhj 3220 17 0.92 0.92 CD cord-005646-xhx9pzhj 3220 18 4 4 CD cord-005646-xhx9pzhj 3220 19 - - SYM cord-005646-xhx9pzhj 3220 20 0.43 0.43 CD cord-005646-xhx9pzhj 3220 21 mL ml NN cord-005646-xhx9pzhj 3220 22 / / SYM cord-005646-xhx9pzhj 3220 23 min min NN cord-005646-xhx9pzhj 3220 24 at at IN cord-005646-xhx9pzhj 3220 25 low low JJ cord-005646-xhx9pzhj 3220 26 and and CC cord-005646-xhx9pzhj 3220 27 high high JJ cord-005646-xhx9pzhj 3220 28 Qb Qb NNP cord-005646-xhx9pzhj 3220 29 ( ( -LRB- cord-005646-xhx9pzhj 3220 30 not not RB cord-005646-xhx9pzhj 3220 31 significantly significantly RB cord-005646-xhx9pzhj 3220 32 different different JJ cord-005646-xhx9pzhj 3220 33 ) ) -RRB- cord-005646-xhx9pzhj 3220 34 . . . cord-005646-xhx9pzhj 3221 1 Whatever whatever WDT cord-005646-xhx9pzhj 3221 2 Qd Qd NNP cord-005646-xhx9pzhj 3221 3 value value NN cord-005646-xhx9pzhj 3221 4 , , , cord-005646-xhx9pzhj 3221 5 the the DT cord-005646-xhx9pzhj 3221 6 VVHDF VVHDF NNP cord-005646-xhx9pzhj 3221 7 procedures procedure NNS cord-005646-xhx9pzhj 3221 8 always always RB cord-005646-xhx9pzhj 3221 9 allowed allow VBD cord-005646-xhx9pzhj 3221 10 higher high JJR cord-005646-xhx9pzhj 3221 11 BCAA BCAA NNP cord-005646-xhx9pzhj 3221 12 and and CC cord-005646-xhx9pzhj 3221 13 c~-keto c~-keto NN cord-005646-xhx9pzhj 3221 14 - - HYPH cord-005646-xhx9pzhj 3221 15 isocaproate isocaproate JJ cord-005646-xhx9pzhj 3221 16 clearances clearance NNS cord-005646-xhx9pzhj 3221 17 as as IN cord-005646-xhx9pzhj 3221 18 compared compare VBN cord-005646-xhx9pzhj 3221 19 with with IN cord-005646-xhx9pzhj 3221 20 the the DT cord-005646-xhx9pzhj 3221 21 corresponding corresponding JJ cord-005646-xhx9pzhj 3221 22 V'~HF V'~HF NNP cord-005646-xhx9pzhj 3221 23 period period NN cord-005646-xhx9pzhj 3221 24 with with IN cord-005646-xhx9pzhj 3221 25 similar similar JJ cord-005646-xhx9pzhj 3221 26 Qb Qb NNP cord-005646-xhx9pzhj 3221 27 . . . cord-005646-xhx9pzhj 3222 1 BCAA BCAA NNP cord-005646-xhx9pzhj 3222 2 clearances clearance NNS cord-005646-xhx9pzhj 3222 3 obtained obtain VBN cord-005646-xhx9pzhj 3222 4 by by IN cord-005646-xhx9pzhj 3222 5 VVHDF VVHDF NNP cord-005646-xhx9pzhj 3222 6 with with IN cord-005646-xhx9pzhj 3222 7 a a DT cord-005646-xhx9pzhj 3222 8 0.5 0.5 CD cord-005646-xhx9pzhj 3222 9 L l NN cord-005646-xhx9pzhj 3222 10 / / SYM cord-005646-xhx9pzhj 3222 11 h h NN cord-005646-xhx9pzhj 3222 12 dialysate dialysate NN cord-005646-xhx9pzhj 3222 13 flow flow NN cord-005646-xhx9pzhj 3222 14 , , , cord-005646-xhx9pzhj 3222 15 were be VBD cord-005646-xhx9pzhj 3222 16 4.1 4.1 CD cord-005646-xhx9pzhj 3222 17 4 4 CD cord-005646-xhx9pzhj 3222 18 - - SYM cord-005646-xhx9pzhj 3222 19 0.5 0.5 CD cord-005646-xhx9pzhj 3222 20 mlJmin mljmin CD cord-005646-xhx9pzhj 3222 21 and and CC cord-005646-xhx9pzhj 3222 22 5.4 5.4 CD cord-005646-xhx9pzhj 3222 23 4 4 CD cord-005646-xhx9pzhj 3222 24 - - SYM cord-005646-xhx9pzhj 3222 25 0.5 0.5 CD cord-005646-xhx9pzhj 3222 26 mL ml NN cord-005646-xhx9pzhj 3222 27 / / SYM cord-005646-xhx9pzhj 3222 28 min min NN cord-005646-xhx9pzhj 3222 29 at at IN cord-005646-xhx9pzhj 3222 30 Iow Iow NNP cord-005646-xhx9pzhj 3222 31 and and CC cord-005646-xhx9pzhj 3222 32 high high JJ cord-005646-xhx9pzhj 3222 33 Qb Qb NNP cord-005646-xhx9pzhj 3222 34 , , , cord-005646-xhx9pzhj 3222 35 respectively respectively RB cord-005646-xhx9pzhj 3222 36 . . . cord-005646-xhx9pzhj 3223 1 The the DT cord-005646-xhx9pzhj 3223 2 concurrent concurrent JJ cord-005646-xhx9pzhj 3223 3 a a DT cord-005646-xhx9pzhj 3223 4 - - HYPH cord-005646-xhx9pzhj 3223 5 keto keto NN cord-005646-xhx9pzhj 3223 6 - - HYPH cord-005646-xhx9pzhj 3223 7 isocaproate isocaproate JJ cord-005646-xhx9pzhj 3223 8 clearances clearance NNS cord-005646-xhx9pzhj 3223 9 were be VBD cord-005646-xhx9pzhj 3223 10 2.5 2.5 CD cord-005646-xhx9pzhj 3223 11 4- 4- CD cord-005646-xhx9pzhj 3223 12 , , , cord-005646-xhx9pzhj 3223 13 . . . cord-005646-xhx9pzhj 3224 1 0,8 0,8 NFP cord-005646-xhx9pzhj 3224 2 mL mL NNP cord-005646-xhx9pzhj 3224 3 / / SYM cord-005646-xhx9pzhj 3224 4 min min NN cord-005646-xhx9pzhj 3224 5 and and CC cord-005646-xhx9pzhj 3224 6 2.9 2.9 CD cord-005646-xhx9pzhj 3225 1 _ _ NNP cord-005646-xhx9pzhj 3225 2 + + CC cord-005646-xhx9pzhj 3226 1 1,0 1,0 CD cord-005646-xhx9pzhj 3226 2 mL ml NN cord-005646-xhx9pzhj 3226 3 / / SYM cord-005646-xhx9pzhj 3226 4 min min NN cord-005646-xhx9pzhj 3226 5 . . . cord-005646-xhx9pzhj 3227 1 At at IN cord-005646-xhx9pzhj 3227 2 both both CC cord-005646-xhx9pzhj 3227 3 Qb Qb NNP cord-005646-xhx9pzhj 3227 4 regimens regimen NNS cord-005646-xhx9pzhj 3227 5 , , , cord-005646-xhx9pzhj 3227 6 BCAA BCAA NNP cord-005646-xhx9pzhj 3227 7 clearances clearance NNS cord-005646-xhx9pzhj 3227 8 provided provide VBN cord-005646-xhx9pzhj 3227 9 by by IN cord-005646-xhx9pzhj 3227 10 VVHDF VVHDF NNP cord-005646-xhx9pzhj 3227 11 were be VBD cord-005646-xhx9pzhj 3227 12 markedly markedly RB cord-005646-xhx9pzhj 3227 13 higher high JJR cord-005646-xhx9pzhj 3227 14 than than IN cord-005646-xhx9pzhj 3227 15 values value NNS cord-005646-xhx9pzhj 3227 16 previously previously RB cord-005646-xhx9pzhj 3227 17 obtained obtain VBN cord-005646-xhx9pzhj 3227 18 with with IN cord-005646-xhx9pzhj 3227 19 peritoneal peritoneal JJ cord-005646-xhx9pzhj 3227 20 dialysis dialysis NN cord-005646-xhx9pzhj 3227 21 in in IN cord-005646-xhx9pzhj 3227 22 human human JJ cord-005646-xhx9pzhj 3227 23 neonates neonate NNS cord-005646-xhx9pzhj 3227 24 with with IN cord-005646-xhx9pzhj 3227 25 MSUD MSUD NNP cord-005646-xhx9pzhj 3227 26 . . . cord-005646-xhx9pzhj 3228 1 The the DT cord-005646-xhx9pzhj 3228 2 management management NN cord-005646-xhx9pzhj 3228 3 of of IN cord-005646-xhx9pzhj 3228 4 renal renal JJ cord-005646-xhx9pzhj 3228 5 failure failure NN cord-005646-xhx9pzhj 3228 6 in in IN cord-005646-xhx9pzhj 3228 7 the the DT cord-005646-xhx9pzhj 3228 8 newborn newborn NN cord-005646-xhx9pzhj 3228 9 is be VBZ cord-005646-xhx9pzhj 3228 10 difficult difficult JJ cord-005646-xhx9pzhj 3228 11 . . . cord-005646-xhx9pzhj 3229 1 When when WRB cord-005646-xhx9pzhj 3229 2 dialysis dialysis NN cord-005646-xhx9pzhj 3229 3 is be VBZ cord-005646-xhx9pzhj 3229 4 instituted institute VBN cord-005646-xhx9pzhj 3229 5 peritoneal peritoneal JJ cord-005646-xhx9pzhj 3229 6 dialysis dialysis NN cord-005646-xhx9pzhj 3229 7 ( ( -LRB- cord-005646-xhx9pzhj 3229 8 PD PD NNP cord-005646-xhx9pzhj 3229 9 ) ) -RRB- cord-005646-xhx9pzhj 3229 10 is be VBZ cord-005646-xhx9pzhj 3229 11 usually usually RB cord-005646-xhx9pzhj 3229 12 the the DT cord-005646-xhx9pzhj 3229 13 technique technique NN cord-005646-xhx9pzhj 3229 14 of of IN cord-005646-xhx9pzhj 3229 15 choice choice NN cord-005646-xhx9pzhj 3229 16 . . . cord-005646-xhx9pzhj 3230 1 This this DT cord-005646-xhx9pzhj 3230 2 is be VBZ cord-005646-xhx9pzhj 3230 3 can can MD cord-005646-xhx9pzhj 3230 4 be be VB cord-005646-xhx9pzhj 3230 5 problematic problematic JJ cord-005646-xhx9pzhj 3230 6 and and CC cord-005646-xhx9pzhj 3230 7 impossible impossible JJ cord-005646-xhx9pzhj 3230 8 in in IN cord-005646-xhx9pzhj 3230 9 some some DT cord-005646-xhx9pzhj 3230 10 patients patient NNS cord-005646-xhx9pzhj 3230 11 with with IN cord-005646-xhx9pzhj 3230 12 pre pre JJ cord-005646-xhx9pzhj 3230 13 - - JJ cord-005646-xhx9pzhj 3230 14 existing existing JJ cord-005646-xhx9pzhj 3230 15 intra intra JJ cord-005646-xhx9pzhj 3230 16 - - JJ cord-005646-xhx9pzhj 3230 17 abdominal abdominal JJ cord-005646-xhx9pzhj 3230 18 pathology pathology NN cord-005646-xhx9pzhj 3230 19 . . . cord-005646-xhx9pzhj 3231 1 Continuous continuous JJ cord-005646-xhx9pzhj 3231 2 arterio arterio NN cord-005646-xhx9pzhj 3231 3 - - HYPH cord-005646-xhx9pzhj 3231 4 venous venous JJ cord-005646-xhx9pzhj 3231 5 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 3231 6 ( ( -LRB- cord-005646-xhx9pzhj 3231 7 CAVH CAVH NNP cord-005646-xhx9pzhj 3231 8 ) ) -RRB- cord-005646-xhx9pzhj 3231 9 has have VBZ cord-005646-xhx9pzhj 3231 10 been be VBN cord-005646-xhx9pzhj 3231 11 described describe VBN cord-005646-xhx9pzhj 3231 12 in in IN cord-005646-xhx9pzhj 3231 13 infants infant NNS cord-005646-xhx9pzhj 3231 14 but but CC cord-005646-xhx9pzhj 3231 15 sick sick JJ cord-005646-xhx9pzhj 3231 16 preterm preterm JJ cord-005646-xhx9pzhj 3231 17 infants infant NNS cord-005646-xhx9pzhj 3231 18 are be VBP cord-005646-xhx9pzhj 3231 19 not not RB cord-005646-xhx9pzhj 3231 20 able able JJ cord-005646-xhx9pzhj 3231 21 to to TO cord-005646-xhx9pzhj 3231 22 support support VB cord-005646-xhx9pzhj 3231 23 the the DT cord-005646-xhx9pzhj 3231 24 circuit circuit NN cord-005646-xhx9pzhj 3231 25 . . . cord-005646-xhx9pzhj 3232 1 I -PRON- PRP cord-005646-xhx9pzhj 3232 2 have have VBP cord-005646-xhx9pzhj 3232 3 devised devise VBN cord-005646-xhx9pzhj 3232 4 a a DT cord-005646-xhx9pzhj 3232 5 means means NN cord-005646-xhx9pzhj 3232 6 of of IN cord-005646-xhx9pzhj 3232 7 having have VBG cord-005646-xhx9pzhj 3232 8 pumped pump VBN cord-005646-xhx9pzhj 3232 9 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 3232 10 in in IN cord-005646-xhx9pzhj 3232 11 small small JJ cord-005646-xhx9pzhj 3232 12 / / SYM cord-005646-xhx9pzhj 3232 13 preterm preterm JJ cord-005646-xhx9pzhj 3232 14 infants infant NNS cord-005646-xhx9pzhj 3232 15 ( ( -LRB- cord-005646-xhx9pzhj 3232 16 PHIS PHIS NNP cord-005646-xhx9pzhj 3232 17 / / SYM cord-005646-xhx9pzhj 3232 18 PI PI NNP cord-005646-xhx9pzhj 3232 19 ) ) -RRB- cord-005646-xhx9pzhj 3232 20 and and CC cord-005646-xhx9pzhj 3232 21 describe describe VB cord-005646-xhx9pzhj 3232 22 its -PRON- PRP$ cord-005646-xhx9pzhj 3232 23 use use NN cord-005646-xhx9pzhj 3232 24 in in IN cord-005646-xhx9pzhj 3232 25 nine nine CD cord-005646-xhx9pzhj 3232 26 patients patient NNS cord-005646-xhx9pzhj 3232 27 ranging range VBG cord-005646-xhx9pzhj 3232 28 in in IN cord-005646-xhx9pzhj 3232 29 size size NN cord-005646-xhx9pzhj 3232 30 from from IN cord-005646-xhx9pzhj 3232 31 750 750 CD cord-005646-xhx9pzhj 3232 32 to to IN cord-005646-xhx9pzhj 3232 33 3000gms 3000gms CD cord-005646-xhx9pzhj 3232 34 for for IN cord-005646-xhx9pzhj 3232 35 periods period NNS cord-005646-xhx9pzhj 3232 36 of of IN cord-005646-xhx9pzhj 3232 37 1 1 CD cord-005646-xhx9pzhj 3232 38 to to TO cord-005646-xhx9pzhj 3232 39 7 7 CD cord-005646-xhx9pzhj 3232 40 days day NNS cord-005646-xhx9pzhj 3232 41 . . . cord-005646-xhx9pzhj 3233 1 Vascular vascular JJ cord-005646-xhx9pzhj 3233 2 access access NN cord-005646-xhx9pzhj 3233 3 was be VBD cord-005646-xhx9pzhj 3233 4 achieved achieve VBN cord-005646-xhx9pzhj 3233 5 through through IN cord-005646-xhx9pzhj 3233 6 24 24 CD cord-005646-xhx9pzhj 3233 7 or or CC cord-005646-xhx9pzhj 3233 8 22 22 CD cord-005646-xhx9pzhj 3233 9 guage guage NN cord-005646-xhx9pzhj 3233 10 cannulae cannulae NNS cord-005646-xhx9pzhj 3233 11 in in IN cord-005646-xhx9pzhj 3233 12 either either CC cord-005646-xhx9pzhj 3233 13 a a DT cord-005646-xhx9pzhj 3233 14 peripheral peripheral JJ cord-005646-xhx9pzhj 3233 15 artery artery NN cord-005646-xhx9pzhj 3233 16 and and CC cord-005646-xhx9pzhj 3233 17 a a DT cord-005646-xhx9pzhj 3233 18 central central JJ cord-005646-xhx9pzhj 3233 19 vein vein NN cord-005646-xhx9pzhj 3233 20 or or CC cord-005646-xhx9pzhj 3233 21 through through IN cord-005646-xhx9pzhj 3233 22 two two CD cord-005646-xhx9pzhj 3233 23 central central JJ cord-005646-xhx9pzhj 3233 24 veins vein NNS cord-005646-xhx9pzhj 3233 25 . . . cord-005646-xhx9pzhj 3234 1 Blood blood NN cord-005646-xhx9pzhj 3234 2 was be VBD cord-005646-xhx9pzhj 3234 3 pumped pump VBN cord-005646-xhx9pzhj 3234 4 out out RP cord-005646-xhx9pzhj 3234 5 using use VBG cord-005646-xhx9pzhj 3234 6 an an DT cord-005646-xhx9pzhj 3234 7 IVAC IVAC NNP cord-005646-xhx9pzhj 3234 8 572 572 CD cord-005646-xhx9pzhj 3234 9 infusion infusion NN cord-005646-xhx9pzhj 3234 10 pump pump NN cord-005646-xhx9pzhj 3234 11 and and CC cord-005646-xhx9pzhj 3234 12 through through IN cord-005646-xhx9pzhj 3234 13 a a DT cord-005646-xhx9pzhj 3234 14 Gambro Gambro NNP cord-005646-xhx9pzhj 3234 15 FH22 FH22 NNP cord-005646-xhx9pzhj 3234 16 haemofilter haemofilter NN cord-005646-xhx9pzhj 3234 17 . . . cord-005646-xhx9pzhj 3235 1 A a DT cord-005646-xhx9pzhj 3235 2 second second JJ cord-005646-xhx9pzhj 3235 3 IVAC IVAC NNP cord-005646-xhx9pzhj 3235 4 pump pump NN cord-005646-xhx9pzhj 3235 5 was be VBD cord-005646-xhx9pzhj 3235 6 used use VBN cord-005646-xhx9pzhj 3235 7 to to TO cord-005646-xhx9pzhj 3235 8 remove remove VB cord-005646-xhx9pzhj 3235 9 haemofiltrate haemofiltrate NN cord-005646-xhx9pzhj 3235 10 from from IN cord-005646-xhx9pzhj 3235 11 the the DT cord-005646-xhx9pzhj 3235 12 filter filter NN cord-005646-xhx9pzhj 3235 13 and and CC cord-005646-xhx9pzhj 3235 14 a a DT cord-005646-xhx9pzhj 3235 15 third third NN cord-005646-xhx9pzhj 3235 16 to to TO cord-005646-xhx9pzhj 3235 17 infuse infuse VB cord-005646-xhx9pzhj 3235 18 replacement replacement NN cord-005646-xhx9pzhj 3235 19 solution solution NN cord-005646-xhx9pzhj 3235 20 . . . cord-005646-xhx9pzhj 3236 1 Removal removal JJ cord-005646-xhx9pzhj 3236 2 rate rate NN cord-005646-xhx9pzhj 3236 3 was be VBD cord-005646-xhx9pzhj 3236 4 set set VBN cord-005646-xhx9pzhj 3236 5 to to TO cord-005646-xhx9pzhj 3236 6 give give VB cord-005646-xhx9pzhj 3236 7 a a DT cord-005646-xhx9pzhj 3236 8 clearance clearance NN cord-005646-xhx9pzhj 3236 9 of of IN cord-005646-xhx9pzhj 3236 10 15mls 15mls NN cord-005646-xhx9pzhj 3236 11 / / SYM cord-005646-xhx9pzhj 3236 12 min/1.73sq.m min/1.73sq.m NN cord-005646-xhx9pzhj 3236 13 and and CC cord-005646-xhx9pzhj 3236 14 blood blood NN cord-005646-xhx9pzhj 3236 15 flow flow NN cord-005646-xhx9pzhj 3236 16 rate rate NN cord-005646-xhx9pzhj 3236 17 set set VBN cord-005646-xhx9pzhj 3236 18 to to IN cord-005646-xhx9pzhj 3236 19 between between IN cord-005646-xhx9pzhj 3236 20 5 5 CD cord-005646-xhx9pzhj 3236 21 and and CC cord-005646-xhx9pzhj 3236 22 10 10 CD cord-005646-xhx9pzhj 3236 23 times time NNS cord-005646-xhx9pzhj 3236 24 the the DT cord-005646-xhx9pzhj 3236 25 removal removal NN cord-005646-xhx9pzhj 3236 26 rate rate NN cord-005646-xhx9pzhj 3236 27 . . . cord-005646-xhx9pzhj 3237 1 Heparin Heparin NNP cord-005646-xhx9pzhj 3237 2 was be VBD cord-005646-xhx9pzhj 3237 3 infused infuse VBN cord-005646-xhx9pzhj 3237 4 into into IN cord-005646-xhx9pzhj 3237 5 the the DT cord-005646-xhx9pzhj 3237 6 circuit circuit NN cord-005646-xhx9pzhj 3237 7 to to TO cord-005646-xhx9pzhj 3237 8 prevent prevent VB cord-005646-xhx9pzhj 3237 9 clotting clotting NN cord-005646-xhx9pzhj 3237 10 of of IN cord-005646-xhx9pzhj 3237 11 the the DT cord-005646-xhx9pzhj 3237 12 filter filter NN cord-005646-xhx9pzhj 3237 13 . . . cord-005646-xhx9pzhj 3238 1 Biochemical biochemical JJ cord-005646-xhx9pzhj 3238 2 and and CC cord-005646-xhx9pzhj 3238 3 fluid fluid JJ cord-005646-xhx9pzhj 3238 4 balance balance NN cord-005646-xhx9pzhj 3238 5 control control NN cord-005646-xhx9pzhj 3238 6 was be VBD cord-005646-xhx9pzhj 3238 7 achieved achieve VBN cord-005646-xhx9pzhj 3238 8 in in IN cord-005646-xhx9pzhj 3238 9 all all DT cord-005646-xhx9pzhj 3238 10 infants infant NNS cord-005646-xhx9pzhj 3238 11 . . . cord-005646-xhx9pzhj 3239 1 Guaranteed guarantee VBN cord-005646-xhx9pzhj 3239 2 fluid fluid JJ cord-005646-xhx9pzhj 3239 3 removal removal NN cord-005646-xhx9pzhj 3239 4 allowed allow VBD cord-005646-xhx9pzhj 3239 5 the the DT cord-005646-xhx9pzhj 3239 6 administration administration NN cord-005646-xhx9pzhj 3239 7 of of IN cord-005646-xhx9pzhj 3239 8 full full JJ cord-005646-xhx9pzhj 3239 9 nutritional nutritional JJ cord-005646-xhx9pzhj 3239 10 support support NN cord-005646-xhx9pzhj 3239 11 . . . cord-005646-xhx9pzhj 3240 1 Four four CD cord-005646-xhx9pzhj 3240 2 patients patient NNS cord-005646-xhx9pzhj 3240 3 died die VBD cord-005646-xhx9pzhj 3240 4 when when WRB cord-005646-xhx9pzhj 3240 5 treatment treatment NN cord-005646-xhx9pzhj 3240 6 was be VBD cord-005646-xhx9pzhj 3240 7 withdrawn withdraw VBN cord-005646-xhx9pzhj 3240 8 because because IN cord-005646-xhx9pzhj 3240 9 of of IN cord-005646-xhx9pzhj 3240 10 an an DT cord-005646-xhx9pzhj 3240 11 untreatable untreatable JJ cord-005646-xhx9pzhj 3240 12 underlying underlying JJ cord-005646-xhx9pzhj 3240 13 problem problem NN cord-005646-xhx9pzhj 3240 14 . . . cord-005646-xhx9pzhj 3241 1 One one CD cord-005646-xhx9pzhj 3241 2 recovered recover VBD cord-005646-xhx9pzhj 3241 3 renal renal JJ cord-005646-xhx9pzhj 3241 4 function function NN cord-005646-xhx9pzhj 3241 5 but but CC cord-005646-xhx9pzhj 3241 6 died die VBD cord-005646-xhx9pzhj 3241 7 some some DT cord-005646-xhx9pzhj 3241 8 weeks week NNS cord-005646-xhx9pzhj 3241 9 later later RB cord-005646-xhx9pzhj 3241 10 from from IN cord-005646-xhx9pzhj 3241 11 unrelated unrelated JJ cord-005646-xhx9pzhj 3241 12 problems problem NNS cord-005646-xhx9pzhj 3241 13 , , , cord-005646-xhx9pzhj 3241 14 three three CD cord-005646-xhx9pzhj 3241 15 survived survive VBD cord-005646-xhx9pzhj 3241 16 and and CC cord-005646-xhx9pzhj 3241 17 recovered recover VBD cord-005646-xhx9pzhj 3241 18 renal renal JJ cord-005646-xhx9pzhj 3241 19 function function NN cord-005646-xhx9pzhj 3241 20 and and CC cord-005646-xhx9pzhj 3241 21 one one CD cord-005646-xhx9pzhj 3241 22 patient patient NN cord-005646-xhx9pzhj 3241 23 is be VBZ cord-005646-xhx9pzhj 3241 24 still still RB cord-005646-xhx9pzhj 3241 25 on on IN cord-005646-xhx9pzhj 3241 26 treatment treatment NN cord-005646-xhx9pzhj 3241 27 . . . cord-005646-xhx9pzhj 3242 1 This this DT cord-005646-xhx9pzhj 3242 2 system system NN cord-005646-xhx9pzhj 3242 3 allows allow VBZ cord-005646-xhx9pzhj 3242 4 a a DT cord-005646-xhx9pzhj 3242 5 secure secure JJ cord-005646-xhx9pzhj 3242 6 means mean NNS cord-005646-xhx9pzhj 3242 7 of of IN cord-005646-xhx9pzhj 3242 8 achieving achieve VBG cord-005646-xhx9pzhj 3242 9 fluid fluid NN cord-005646-xhx9pzhj 3242 10 and and CC cord-005646-xhx9pzhj 3242 11 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3242 12 control control NN cord-005646-xhx9pzhj 3242 13 in in IN cord-005646-xhx9pzhj 3242 14 the the DT cord-005646-xhx9pzhj 3242 15 preterm preterm JJ cord-005646-xhx9pzhj 3242 16 infant infant NN cord-005646-xhx9pzhj 3242 17 . . . cord-005646-xhx9pzhj 3243 1 The the DT cord-005646-xhx9pzhj 3243 2 use use NN cord-005646-xhx9pzhj 3243 3 of of IN cord-005646-xhx9pzhj 3243 4 this this DT cord-005646-xhx9pzhj 3243 5 technique technique NN cord-005646-xhx9pzhj 3243 6 may may MD cord-005646-xhx9pzhj 3243 7 allow allow VB cord-005646-xhx9pzhj 3243 8 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 3243 9 to to TO cord-005646-xhx9pzhj 3243 10 become become VB cord-005646-xhx9pzhj 3243 11 as as IN cord-005646-xhx9pzhj 3243 12 applicable applicable JJ cord-005646-xhx9pzhj 3243 13 to to IN cord-005646-xhx9pzhj 3243 14 preterm preterm JJR cord-005646-xhx9pzhj 3243 15 infants infant NNS cord-005646-xhx9pzhj 3243 16 as as IN cord-005646-xhx9pzhj 3243 17 it -PRON- PRP cord-005646-xhx9pzhj 3243 18 is be VBZ cord-005646-xhx9pzhj 3243 19 to to IN cord-005646-xhx9pzhj 3243 20 older old JJR cord-005646-xhx9pzhj 3243 21 children child NNS cord-005646-xhx9pzhj 3243 22 and and CC cord-005646-xhx9pzhj 3243 23 adults adult NNS cord-005646-xhx9pzhj 3243 24 . . . cord-005646-xhx9pzhj 3244 1 Unibrtunately unibrtunately RB cord-005646-xhx9pzhj 3244 2 , , , cord-005646-xhx9pzhj 3244 3 children child NNS cord-005646-xhx9pzhj 3244 4 often often RB cord-005646-xhx9pzhj 3244 5 receive receive VBP cord-005646-xhx9pzhj 3244 6 no no DT cord-005646-xhx9pzhj 3244 7 treatment treatment NN cord-005646-xhx9pzhj 3244 8 , , , cord-005646-xhx9pzhj 3244 9 or or CC cord-005646-xhx9pzhj 3244 10 inadequate inadequate JJ cord-005646-xhx9pzhj 3244 11 treatment treatment NN cord-005646-xhx9pzhj 3244 12 for for IN cord-005646-xhx9pzhj 3244 13 pain pain NN cord-005646-xhx9pzhj 3244 14 and and CC cord-005646-xhx9pzhj 3244 15 painful painful JJ cord-005646-xhx9pzhj 3244 16 procedures procedure NNS cord-005646-xhx9pzhj 3244 17 . . . cord-005646-xhx9pzhj 3245 1 This this DT cord-005646-xhx9pzhj 3245 2 prospective prospective NN cord-005646-xhx9pzhj 3245 3 , , , cord-005646-xhx9pzhj 3245 4 multicentric multicentric JJ cord-005646-xhx9pzhj 3245 5 study study NN cord-005646-xhx9pzhj 3245 6 focuses focus VBZ cord-005646-xhx9pzhj 3245 7 on on IN cord-005646-xhx9pzhj 3245 8 the the DT cord-005646-xhx9pzhj 3245 9 efficacy efficacy NN cord-005646-xhx9pzhj 3245 10 , , , cord-005646-xhx9pzhj 3245 11 safety safety NN cord-005646-xhx9pzhj 3245 12 and and CC cord-005646-xhx9pzhj 3245 13 side side NN cord-005646-xhx9pzhj 3245 14 effects effect NNS cord-005646-xhx9pzhj 3245 15 of of IN cord-005646-xhx9pzhj 3245 16 Novalgin Novalgin NNP cord-005646-xhx9pzhj 3245 17 ( ( -LRB- cord-005646-xhx9pzhj 3245 18 Metamizol Metamizol NNP cord-005646-xhx9pzhj 3245 19 sodium sodium NN cord-005646-xhx9pzhj 3245 20 ) ) -RRB- cord-005646-xhx9pzhj 3245 21 for for IN cord-005646-xhx9pzhj 3245 22 this this DT cord-005646-xhx9pzhj 3245 23 indication indication NN cord-005646-xhx9pzhj 3245 24 . . . cord-005646-xhx9pzhj 3246 1 PATIENTS patient NNS cord-005646-xhx9pzhj 3246 2 AND and CC cord-005646-xhx9pzhj 3246 3 METHOD method NN cord-005646-xhx9pzhj 3246 4 : : : cord-005646-xhx9pzhj 3247 1 Novalgin Novalgin NNP cord-005646-xhx9pzhj 3247 2 was be VBD cord-005646-xhx9pzhj 3247 3 administered administer VBN cord-005646-xhx9pzhj 3247 4 to to IN cord-005646-xhx9pzhj 3247 5 56 56 CD cord-005646-xhx9pzhj 3247 6 children child NNS cord-005646-xhx9pzhj 3247 7 , , , cord-005646-xhx9pzhj 3247 8 aged age VBN cord-005646-xhx9pzhj 3247 9 between between IN cord-005646-xhx9pzhj 3247 10 6 6 CD cord-005646-xhx9pzhj 3247 11 - - SYM cord-005646-xhx9pzhj 3247 12 16 16 CD cord-005646-xhx9pzhj 3247 13 years year NNS cord-005646-xhx9pzhj 3247 14 , , , cord-005646-xhx9pzhj 3247 15 with with IN cord-005646-xhx9pzhj 3247 16 acute acute JJ cord-005646-xhx9pzhj 3247 17 , , , cord-005646-xhx9pzhj 3247 18 postoperative postoperative JJ cord-005646-xhx9pzhj 3247 19 or or CC cord-005646-xhx9pzhj 3247 20 procedural procedural JJ cord-005646-xhx9pzhj 3247 21 pain pain NN cord-005646-xhx9pzhj 3247 22 . . . cord-005646-xhx9pzhj 3248 1 Novalgin Novalgin NNP cord-005646-xhx9pzhj 3248 2 ( ( -LRB- cord-005646-xhx9pzhj 3248 3 10 10 CD cord-005646-xhx9pzhj 3248 4 - - SYM cord-005646-xhx9pzhj 3248 5 15 15 CD cord-005646-xhx9pzhj 3248 6 mg mg NNP cord-005646-xhx9pzhj 3248 7 / / SYM cord-005646-xhx9pzhj 3248 8 kg kg NNP cord-005646-xhx9pzhj 3248 9 ) ) -RRB- cord-005646-xhx9pzhj 3248 10 was be VBD cord-005646-xhx9pzhj 3248 11 given give VBN cord-005646-xhx9pzhj 3248 12 6 6 CD cord-005646-xhx9pzhj 3248 13 - - SYM cord-005646-xhx9pzhj 3248 14 8 8 CD cord-005646-xhx9pzhj 3248 15 hourly hourly JJ cord-005646-xhx9pzhj 3248 16 IV IV NNP cord-005646-xhx9pzhj 3248 17 or or CC cord-005646-xhx9pzhj 3248 18 IM IM NNP cord-005646-xhx9pzhj 3248 19 respectively respectively RB cord-005646-xhx9pzhj 3248 20 , , , cord-005646-xhx9pzhj 3248 21 in in IN cord-005646-xhx9pzhj 3248 22 some some DT cord-005646-xhx9pzhj 3248 23 cases case NNS cord-005646-xhx9pzhj 3248 24 ( ( -LRB- cord-005646-xhx9pzhj 3248 25 15 15 CD cord-005646-xhx9pzhj 3248 26 ) ) -RRB- cord-005646-xhx9pzhj 3248 27 in in IN cord-005646-xhx9pzhj 3248 28 combination combination NN cord-005646-xhx9pzhj 3248 29 with with IN cord-005646-xhx9pzhj 3248 30 opioids opioid NNS cord-005646-xhx9pzhj 3248 31 ( ( -LRB- cord-005646-xhx9pzhj 3248 32 Tramadol Tramadol NNP cord-005646-xhx9pzhj 3248 33 10 10 CD cord-005646-xhx9pzhj 3248 34 , , , cord-005646-xhx9pzhj 3248 35 Piritramid Piritramid NNP cord-005646-xhx9pzhj 3248 36 3 3 CD cord-005646-xhx9pzhj 3248 37 , , , cord-005646-xhx9pzhj 3248 38 Butorphanol Butorphanol NNP cord-005646-xhx9pzhj 3248 39 2 2 CD cord-005646-xhx9pzhj 3248 40 ) ) -RRB- cord-005646-xhx9pzhj 3248 41 . . . cord-005646-xhx9pzhj 3249 1 The the DT cord-005646-xhx9pzhj 3249 2 pain pain NN cord-005646-xhx9pzhj 3249 3 relief relief NN cord-005646-xhx9pzhj 3249 4 was be VBD cord-005646-xhx9pzhj 3249 5 assessed assess VBN cord-005646-xhx9pzhj 3249 6 by by IN cord-005646-xhx9pzhj 3249 7 six six CD cord-005646-xhx9pzhj 3249 8 - - HYPH cord-005646-xhx9pzhj 3249 9 step step NN cord-005646-xhx9pzhj 3249 10 Verbal verbal JJ cord-005646-xhx9pzhj 3249 11 Rating rating NN cord-005646-xhx9pzhj 3249 12 Scale scale NN cord-005646-xhx9pzhj 3249 13 ( ( -LRB- cord-005646-xhx9pzhj 3249 14 VRS VRS NNP cord-005646-xhx9pzhj 3249 15 ) ) -RRB- cord-005646-xhx9pzhj 3249 16 from from IN cord-005646-xhx9pzhj 3249 17 0 0 CD cord-005646-xhx9pzhj 3249 18 to to IN cord-005646-xhx9pzhj 3249 19 5 5 CD cord-005646-xhx9pzhj 3249 20 , , , cord-005646-xhx9pzhj 3249 21 Vital vital JJ cord-005646-xhx9pzhj 3249 22 signs sign NNS cord-005646-xhx9pzhj 3249 23 were be VBD cord-005646-xhx9pzhj 3249 24 monitored monitor VBN cord-005646-xhx9pzhj 3249 25 , , , cord-005646-xhx9pzhj 3249 26 the the DT cord-005646-xhx9pzhj 3249 27 side side NN cord-005646-xhx9pzhj 3249 28 effects effect NNS cord-005646-xhx9pzhj 3249 29 , , , cord-005646-xhx9pzhj 3249 30 that that WDT cord-005646-xhx9pzhj 3249 31 occured occur VBD cord-005646-xhx9pzhj 3249 32 were be VBD cord-005646-xhx9pzhj 3249 33 recorded record VBN cord-005646-xhx9pzhj 3249 34 . . . cord-005646-xhx9pzhj 3250 1 RESULTS result NNS cord-005646-xhx9pzhj 3250 2 : : : cord-005646-xhx9pzhj 3251 1 Pain pain NN cord-005646-xhx9pzhj 3251 2 relief relief NN cord-005646-xhx9pzhj 3251 3 was be VBD cord-005646-xhx9pzhj 3251 4 good good JJ cord-005646-xhx9pzhj 3252 1 ( ( -LRB- cord-005646-xhx9pzhj 3252 2 VRS VRS NNP cord-005646-xhx9pzhj 3252 3 less less RBR cord-005646-xhx9pzhj 3252 4 2 2 CD cord-005646-xhx9pzhj 3252 5 ) ) -RRB- cord-005646-xhx9pzhj 3252 6 in in IN cord-005646-xhx9pzhj 3252 7 53 53 CD cord-005646-xhx9pzhj 3252 8 children child NNS cord-005646-xhx9pzhj 3252 9 -94.6 -94.6 : cord-005646-xhx9pzhj 3252 10 % % NN cord-005646-xhx9pzhj 3252 11 of of IN cord-005646-xhx9pzhj 3252 12 study study NN cord-005646-xhx9pzhj 3252 13 patients patient NNS cord-005646-xhx9pzhj 3252 14 . . . cord-005646-xhx9pzhj 3253 1 Novalgin Novalgin NNP cord-005646-xhx9pzhj 3253 2 was be VBD cord-005646-xhx9pzhj 3253 3 very very RB cord-005646-xhx9pzhj 3253 4 well well RB cord-005646-xhx9pzhj 3253 5 tolerated tolerate VBN cord-005646-xhx9pzhj 3253 6 , , , cord-005646-xhx9pzhj 3253 7 only only RB cord-005646-xhx9pzhj 3253 8 one one CD cord-005646-xhx9pzhj 3253 9 patient patient NN cord-005646-xhx9pzhj 3253 10 had have VBD cord-005646-xhx9pzhj 3253 11 adverse adverse JJ cord-005646-xhx9pzhj 3253 12 reaction reaction NN cord-005646-xhx9pzhj 3253 13 -hyperpyrexia -hyperpyrexia : cord-005646-xhx9pzhj 3254 1 following follow VBG cord-005646-xhx9pzhj 3254 2 intravenous intravenous JJ cord-005646-xhx9pzhj 3254 3 application application NN cord-005646-xhx9pzhj 3254 4 of of IN cord-005646-xhx9pzhj 3254 5 the the DT cord-005646-xhx9pzhj 3254 6 drug drug NN cord-005646-xhx9pzhj 3254 7 . . . cord-005646-xhx9pzhj 3255 1 DISCUSSION discussion NN cord-005646-xhx9pzhj 3255 2 : : : cord-005646-xhx9pzhj 3256 1 Novalgin Novalgin NNP cord-005646-xhx9pzhj 3256 2 ( ( -LRB- cord-005646-xhx9pzhj 3256 3 Metamizol metamizol JJ cord-005646-xhx9pzhj 3256 4 sodium sodium NN cord-005646-xhx9pzhj 3256 5 ) ) -RRB- cord-005646-xhx9pzhj 3256 6 is be VBZ cord-005646-xhx9pzhj 3256 7 safe safe JJ cord-005646-xhx9pzhj 3256 8 and and CC cord-005646-xhx9pzhj 3256 9 effective effective JJ cord-005646-xhx9pzhj 3256 10 drug drug NN cord-005646-xhx9pzhj 3256 11 in in IN cord-005646-xhx9pzhj 3256 12 the the DT cord-005646-xhx9pzhj 3256 13 management management NN cord-005646-xhx9pzhj 3256 14 of of IN cord-005646-xhx9pzhj 3256 15 acute acute JJ cord-005646-xhx9pzhj 3256 16 pain pain NN cord-005646-xhx9pzhj 3256 17 in in IN cord-005646-xhx9pzhj 3256 18 children child NNS cord-005646-xhx9pzhj 3256 19 with with IN cord-005646-xhx9pzhj 3256 20 low low JJ cord-005646-xhx9pzhj 3256 21 incidence incidence NN cord-005646-xhx9pzhj 3256 22 of of IN cord-005646-xhx9pzhj 3256 23 side side NN cord-005646-xhx9pzhj 3256 24 effects effect NNS cord-005646-xhx9pzhj 3256 25 . . . cord-005646-xhx9pzhj 3257 1 Obie Obie NNP cord-005646-xhx9pzhj 3257 2 ~ ~ NFP cord-005646-xhx9pzhj 3257 3 qve qve NN cord-005646-xhx9pzhj 3257 4 : : : cord-005646-xhx9pzhj 3257 5 a a DT cord-005646-xhx9pzhj 3257 6 prostx prostx NNP cord-005646-xhx9pzhj 3257 7 ~ ~ NFP cord-005646-xhx9pzhj 3257 8 tive tive JJ cord-005646-xhx9pzhj 3257 9 study study NN cord-005646-xhx9pzhj 3257 10 comparing compare VBG cord-005646-xhx9pzhj 3257 11 simultaneous simultaneous JJ cord-005646-xhx9pzhj 3257 12 , , , cord-005646-xhx9pzhj 3257 13 indepeadent indepeadent JJ cord-005646-xhx9pzhj 3257 14 ratings rating NNS cord-005646-xhx9pzhj 3257 15 conducted conduct VBN cord-005646-xhx9pzhj 3257 16 by by IN cord-005646-xhx9pzhj 3257 17 intensi~4sts intensi~4st NNS cord-005646-xhx9pzhj 3257 18 using use VBG cord-005646-xhx9pzhj 3257 19 an an DT cord-005646-xhx9pzhj 3257 20 american american JJ cord-005646-xhx9pzhj 3257 21 ( ( -LRB- cord-005646-xhx9pzhj 3257 22 COMFORT COMFORT NNP cord-005646-xhx9pzhj 3257 23 ) ) -RRB- cord-005646-xhx9pzhj 3257 24 and and CC cord-005646-xhx9pzhj 3257 25 an an DT cord-005646-xhx9pzhj 3257 26 european european JJ cord-005646-xhx9pzhj 3257 27 CHARTWIG CHARTWIG NNP cord-005646-xhx9pzhj 3257 28 ) ) -RRB- cord-005646-xhx9pzhj 3257 29 sedation sedation NN cord-005646-xhx9pzhj 3257 30 scale scale NN cord-005646-xhx9pzhj 3257 31 for for IN cord-005646-xhx9pzhj 3257 32 mechanically mechanically RB cord-005646-xhx9pzhj 3257 33 ventilated ventilate VBN cord-005646-xhx9pzhj 3257 34 pediatric pediatric JJ cord-005646-xhx9pzhj 3257 35 patients patient NNS cord-005646-xhx9pzhj 3257 36 . . . cord-005646-xhx9pzhj 3258 1 Measurements measurement NNS cord-005646-xhx9pzhj 3258 2 and and CC cord-005646-xhx9pzhj 3258 3 results result NNS cord-005646-xhx9pzhj 3259 1 : : : cord-005646-xhx9pzhj 3259 2 the the DT cord-005646-xhx9pzhj 3259 3 study study NN cord-005646-xhx9pzhj 3259 4 comprised comprise VBD cord-005646-xhx9pzhj 3259 5 30 30 CD cord-005646-xhx9pzhj 3259 6 observations observation NNS cord-005646-xhx9pzhj 3259 7 in in IN cord-005646-xhx9pzhj 3259 8 18 18 CD cord-005646-xhx9pzhj 3259 9 mechanically mechanically RB cord-005646-xhx9pzhj 3259 10 ventilated ventilate VBN cord-005646-xhx9pzhj 3259 11 pediatric pediatric JJ cord-005646-xhx9pzhj 3259 12 patients patient NNS cord-005646-xhx9pzhj 3259 13 ( ( -LRB- cord-005646-xhx9pzhj 3259 14 aged age VBN cord-005646-xhx9pzhj 3259 15 16 16 CD cord-005646-xhx9pzhj 3259 16 days day NNS cord-005646-xhx9pzhj 3259 17 to to IN cord-005646-xhx9pzhj 3259 18 5 5 CD cord-005646-xhx9pzhj 3259 19 years year NNS cord-005646-xhx9pzhj 3259 20 ) ) -RRB- cord-005646-xhx9pzhj 3259 21 in in IN cord-005646-xhx9pzhj 3259 22 a a DT cord-005646-xhx9pzhj 3259 23 pediatric pediatric JJ cord-005646-xhx9pzhj 3259 24 intensive intensive JJ cord-005646-xhx9pzhj 3259 25 care care NN cord-005646-xhx9pzhj 3259 26 unit unit NN cord-005646-xhx9pzhj 3259 27 ( ( -LRB- cord-005646-xhx9pzhj 3259 28 from from IN cord-005646-xhx9pzhj 3259 29 March March NNP cord-005646-xhx9pzhj 3259 30 1995 1995 CD cord-005646-xhx9pzhj 3259 31 to to IN cord-005646-xhx9pzhj 3259 32 January January NNP cord-005646-xhx9pzhj 3259 33 1996 1996 CD cord-005646-xhx9pzhj 3259 34 . . . cord-005646-xhx9pzhj 3260 1 Each each DT cord-005646-xhx9pzhj 3260 2 patient patient NN cord-005646-xhx9pzhj 3260 3 was be VBD cord-005646-xhx9pzhj 3260 4 sedated sedate VBN cord-005646-xhx9pzhj 3260 5 by by IN cord-005646-xhx9pzhj 3260 6 his -PRON- PRP$ cord-005646-xhx9pzhj 3260 7 / / SYM cord-005646-xhx9pzhj 3260 8 her -PRON- PRP$ cord-005646-xhx9pzhj 3260 9 managing manage VBG cord-005646-xhx9pzhj 3260 10 physician physician NN cord-005646-xhx9pzhj 3260 11 with with IN cord-005646-xhx9pzhj 3260 12 opiates opiate NNS cord-005646-xhx9pzhj 3260 13 , , , cord-005646-xhx9pzhj 3260 14 benzodiazepines benzodiazepine NNS cord-005646-xhx9pzhj 3260 15 , , , cord-005646-xhx9pzhj 3260 16 barbiturates barbiturate NNS cord-005646-xhx9pzhj 3260 17 , , , cord-005646-xhx9pzhj 3260 18 used use VBD cord-005646-xhx9pzhj 3260 19 isolated isolate VBN cord-005646-xhx9pzhj 3260 20 or or CC cord-005646-xhx9pzhj 3260 21 in in IN cord-005646-xhx9pzhj 3260 22 combination combination NN cord-005646-xhx9pzhj 3260 23 . . . cord-005646-xhx9pzhj 3261 1 Each each DT cord-005646-xhx9pzhj 3261 2 observation observation NN cord-005646-xhx9pzhj 3261 3 consisted consist VBD cord-005646-xhx9pzhj 3261 4 of of IN cord-005646-xhx9pzhj 3261 5 a a DT cord-005646-xhx9pzhj 3261 6 3-miD 3-mid CD cord-005646-xhx9pzhj 3261 7 period period NN cord-005646-xhx9pzhj 3261 8 of of IN cord-005646-xhx9pzhj 3261 9 oly oly NNP cord-005646-xhx9pzhj 3261 10 ~ ~ NNP cord-005646-xhx9pzhj 3261 11 ervatien ervatien NNP cord-005646-xhx9pzhj 3261 12 of of IN cord-005646-xhx9pzhj 3261 13 the the DT cord-005646-xhx9pzhj 3261 14 patient patient NN cord-005646-xhx9pzhj 3261 15 in in IN cord-005646-xhx9pzhj 3261 16 his -PRON- PRP$ cord-005646-xhx9pzhj 3261 17 or or CC cord-005646-xhx9pzhj 3261 18 her -PRON- PRP$ cord-005646-xhx9pzhj 3261 19 pediatric pediatric JJ cord-005646-xhx9pzhj 3261 20 ICU ICU NNP cord-005646-xhx9pzhj 3261 21 bed bed NN cord-005646-xhx9pzhj 3261 22 , , , cord-005646-xhx9pzhj 3261 23 After after IN cord-005646-xhx9pzhj 3261 24 each each DT cord-005646-xhx9pzhj 3261 25 observation observation NN cord-005646-xhx9pzhj 3261 26 , , , cord-005646-xhx9pzhj 3261 27 the the DT cord-005646-xhx9pzhj 3261 28 COMFORT COMFORT NNP cord-005646-xhx9pzhj 3261 29 ( ( -LRB- cord-005646-xhx9pzhj 3261 30 analyses analyse VBZ cord-005646-xhx9pzhj 3261 31 8 8 CD cord-005646-xhx9pzhj 3261 32 dimensional dimensional JJ cord-005646-xhx9pzhj 3261 33 physiologic physiologic JJ cord-005646-xhx9pzhj 3261 34 and and CC cord-005646-xhx9pzhj 3261 35 behavioral behavioral JJ cord-005646-xhx9pzhj 3261 36 subscores subscore NNS cord-005646-xhx9pzhj 3261 37 -range -range VBD cord-005646-xhx9pzhj 3261 38 8 8 CD cord-005646-xhx9pzhj 3261 39 to to TO cord-005646-xhx9pzhj 3261 40 40 40 CD cord-005646-xhx9pzhj 3261 41 paints paint NNS cord-005646-xhx9pzhj 3261 42 ) ) -RRB- cord-005646-xhx9pzhj 3261 43 and and CC cord-005646-xhx9pzhj 3261 44 HARTWIG HARTWIG NNP cord-005646-xhx9pzhj 3261 45 ( ( -LRB- cord-005646-xhx9pzhj 3261 46 analyses analyse VBZ cord-005646-xhx9pzhj 3261 47 4 4 CD cord-005646-xhx9pzhj 3261 48 dimensional dimensional JJ cord-005646-xhx9pzhj 3261 49 behavioral behavioral JJ cord-005646-xhx9pzhj 3261 50 subsenres subsenre NNS cord-005646-xhx9pzhj 3261 51 -range -range : cord-005646-xhx9pzhj 3261 52 8 8 CD cord-005646-xhx9pzhj 3261 53 to to TO cord-005646-xhx9pzhj 3261 54 25 25 CD cord-005646-xhx9pzhj 3261 55 points point NNS cord-005646-xhx9pzhj 3261 56 ) ) -RRB- cord-005646-xhx9pzhj 3261 57 were be VBD cord-005646-xhx9pzhj 3261 58 performed perform VBN cord-005646-xhx9pzhj 3261 59 by by IN cord-005646-xhx9pzhj 3261 60 the the DT cord-005646-xhx9pzhj 3261 61 intensivist intensivist NN cord-005646-xhx9pzhj 3261 62 . . . cord-005646-xhx9pzhj 3262 1 We -PRON- PRP cord-005646-xhx9pzhj 3262 2 established establish VBD cord-005646-xhx9pzhj 3262 3 the the DT cord-005646-xhx9pzhj 3262 4 COMFORT comfort NN cord-005646-xhx9pzhj 3262 5 scores score NNS cord-005646-xhx9pzhj 3262 6 ~ ~ NFP cord-005646-xhx9pzhj 3262 7 correspanding correspande VBG cord-005646-xhx9pzhj 3262 8 to to TO cord-005646-xhx9pzhj 3262 9 adequate adequate JJ cord-005646-xhx9pzhj 3262 10 ( ( -LRB- cord-005646-xhx9pzhj 3262 11 range range NN cord-005646-xhx9pzhj 3262 12 17 17 CD cord-005646-xhx9pzhj 3262 13 to to IN cord-005646-xhx9pzhj 3262 14 26 26 CD cord-005646-xhx9pzhj 3262 15 ) ) -RRB- cord-005646-xhx9pzhj 3262 16 , , , cord-005646-xhx9pzhj 3262 17 excessive excessive JJ cord-005646-xhx9pzhj 3262 18 ( ( -LRB- cord-005646-xhx9pzhj 3262 19 range range NN cord-005646-xhx9pzhj 3262 20 8 8 CD cord-005646-xhx9pzhj 3262 21 to to IN cord-005646-xhx9pzhj 3262 22 16 16 CD cord-005646-xhx9pzhj 3262 23 ) ) -RRB- cord-005646-xhx9pzhj 3262 24 , , , cord-005646-xhx9pzhj 3262 25 and and CC cord-005646-xhx9pzhj 3262 26 inadequate inadequate JJ cord-005646-xhx9pzhj 3262 27 ( ( -LRB- cord-005646-xhx9pzhj 3262 28 range range VBP cord-005646-xhx9pzhj 3262 29 27 27 CD cord-005646-xhx9pzhj 3262 30 to to IN cord-005646-xhx9pzhj 3262 31 40 40 CD cord-005646-xhx9pzhj 3262 32 ) ) -RRB- cord-005646-xhx9pzhj 3262 33 sedation sedation NN cord-005646-xhx9pzhj 3262 34 ; ; : cord-005646-xhx9pzhj 3262 35 and and CC cord-005646-xhx9pzhj 3262 36 , , , cord-005646-xhx9pzhj 3262 37 HARTWlG HARTWlG NNP cord-005646-xhx9pzhj 3262 38 scores score NNS cord-005646-xhx9pzhj 3262 39 z z NNP cord-005646-xhx9pzhj 3262 40 correslxmding correslxmde VBG cord-005646-xhx9pzhj 3262 41 to to TO cord-005646-xhx9pzhj 3262 42 adequate adequate JJ cord-005646-xhx9pzhj 3262 43 ( ( -LRB- cord-005646-xhx9pzhj 3262 44 range range VB cord-005646-xhx9pzhj 3262 45 15 15 CD cord-005646-xhx9pzhj 3262 46 to to IN cord-005646-xhx9pzhj 3262 47 t8 t8 NNP cord-005646-xhx9pzhj 3262 48 ) ) -RRB- cord-005646-xhx9pzhj 3262 49 , , , cord-005646-xhx9pzhj 3262 50 excessive excessive JJ cord-005646-xhx9pzhj 3262 51 ( ( -LRB- cord-005646-xhx9pzhj 3262 52 range range NN cord-005646-xhx9pzhj 3262 53 8 8 CD cord-005646-xhx9pzhj 3262 54 to to IN cord-005646-xhx9pzhj 3262 55 141 141 CD cord-005646-xhx9pzhj 3262 56 , , , cord-005646-xhx9pzhj 3262 57 and and CC cord-005646-xhx9pzhj 3262 58 inadequate inadequate JJ cord-005646-xhx9pzhj 3262 59 ( ( -LRB- cord-005646-xhx9pzhj 3262 60 range range VB cord-005646-xhx9pzhj 3262 61 19 19 CD cord-005646-xhx9pzhj 3262 62 to to IN cord-005646-xhx9pzhj 3262 63 25 25 CD cord-005646-xhx9pzhj 3262 64 ) ) -RRB- cord-005646-xhx9pzhj 3262 65 . . . cord-005646-xhx9pzhj 3263 1 Statistical statistical JJ cord-005646-xhx9pzhj 3263 2 mmlysisJ mmlysisJ NNP cord-005646-xhx9pzhj 3263 3 : : : cord-005646-xhx9pzhj 3263 4 agreement agreement NN cord-005646-xhx9pzhj 3263 5 rate rate NN cord-005646-xhx9pzhj 3263 6 ( ( -LRB- cord-005646-xhx9pzhj 3263 7 kappa kappa NNP cord-005646-xhx9pzhj 3263 8 ) ) -RRB- cord-005646-xhx9pzhj 3263 9 and and CC cord-005646-xhx9pzhj 3263 10 p p NN cord-005646-xhx9pzhj 3263 11 < < XX cord-005646-xhx9pzhj 3263 12 .01 .01 . cord-005646-xhx9pzhj 3264 1 was be VBD cord-005646-xhx9pzhj 3264 2 considere considere JJ cord-005646-xhx9pzhj 3265 1 d d NNP cord-005646-xhx9pzhj 3265 2 s!l~ s!l~ NNP cord-005646-xhx9pzhj 3266 1 nificant nificant JJ cord-005646-xhx9pzhj 3266 2 . . . cord-005646-xhx9pzhj 3267 1 COMFORT COMFORT NNP cord-005646-xhx9pzhj 3267 2 18 18 CD cord-005646-xhx9pzhj 3267 3 ( ( -LRB- cord-005646-xhx9pzhj 3267 4 60.9 60.9 CD cord-005646-xhx9pzhj 3267 5 % % NN cord-005646-xhx9pzhj 3267 6 ) ) -RRB- cord-005646-xhx9pzhj 3267 7 2 2 CD cord-005646-xhx9pzhj 3267 8 ( ( -LRB- cord-005646-xhx9pzhj 3267 9 6,6%/ 6,6%/ CD cord-005646-xhx9pzhj 3267 10 10 10 CD cord-005646-xhx9pzhj 3267 11 ( ( -LRB- cord-005646-xhx9pzhj 3267 12 33.4 33.4 CD cord-005646-xhx9pzhj 3267 13 % % NN cord-005646-xhx9pzhj 3267 14 ) ) -RRB- cord-005646-xhx9pzhj 3268 1 HAP HAP NNP cord-005646-xhx9pzhj 3268 2 , , , cord-005646-xhx9pzhj 3268 3 TWIG twig NN cord-005646-xhx9pzhj 3268 4 , , , cord-005646-xhx9pzhj 3268 5 17 17 CD cord-005646-xhx9pzhj 3268 6 ( ( -LRB- cord-005646-xhx9pzhj 3268 7 56.6 56.6 CD cord-005646-xhx9pzhj 3268 8 % % NN cord-005646-xhx9pzhj 3268 9 ) ) -RRB- cord-005646-xhx9pzhj 3268 10 7 7 CD cord-005646-xhx9pzhj 3268 11 ( ( -LRB- cord-005646-xhx9pzhj 3268 12 23.4 23.4 CD cord-005646-xhx9pzhj 3268 13 % % NN cord-005646-xhx9pzhj 3268 14 ) ) -RRB- cord-005646-xhx9pzhj 3268 15 6 6 CD cord-005646-xhx9pzhj 3268 16 ( ( -LRB- cord-005646-xhx9pzhj 3268 17 20.0 20.0 CD cord-005646-xhx9pzhj 3268 18 % % NN cord-005646-xhx9pzhj 3268 19 ) ) -RRB- cord-005646-xhx9pzhj 3269 1 To to IN cord-005646-xhx9pzhj 3269 2 the the DT cord-005646-xhx9pzhj 3269 3 COMFORT comfort NN cord-005646-xhx9pzhj 3269 4 score score NN cord-005646-xhx9pzhj 3269 5 , , , cord-005646-xhx9pzhj 3269 6 the the DT cord-005646-xhx9pzhj 3269 7 average average NN cord-005646-xhx9pzhj 3269 8 for for IN cord-005646-xhx9pzhj 3269 9 adequately adequately RB cord-005646-xhx9pzhj 3269 10 sedated sedate VBN cord-005646-xhx9pzhj 3269 11 , , , cord-005646-xhx9pzhj 3269 12 inadequately inadequately RB cord-005646-xhx9pzhj 3269 13 sedated sedate VBN cord-005646-xhx9pzhj 3269 14 , , , cord-005646-xhx9pzhj 3269 15 and and CC cord-005646-xhx9pzhj 3269 16 too too RB cord-005646-xhx9pzhj 3269 17 sedated sedated JJ cord-005646-xhx9pzhj 3269 18 was be VBD cord-005646-xhx9pzhj 3269 19 20.28 20.28 CD cord-005646-xhx9pzhj 3269 20 + + SYM cord-005646-xhx9pzhj 3269 21 -2.78 -2.78 CD cord-005646-xhx9pzhj 3269 22 , , , cord-005646-xhx9pzhj 3269 23 2Z5_+0.70 2z5_+0.70 CD cord-005646-xhx9pzhj 3269 24 , , , cord-005646-xhx9pzhj 3269 25 and and CC cord-005646-xhx9pzhj 3269 26 15A.+_L10 15a.+_l10 CD cord-005646-xhx9pzhj 3269 27 , , , cord-005646-xhx9pzhj 3269 28 respectively respectively RB cord-005646-xhx9pzhj 3269 29 . . . cord-005646-xhx9pzhj 3270 1 And and CC cord-005646-xhx9pzhj 3270 2 to to IN cord-005646-xhx9pzhj 3270 3 the the DT cord-005646-xhx9pzhj 3270 4 HA HA NNP cord-005646-xhx9pzhj 3270 5 ~ ~ NFP cord-005646-xhx9pzhj 3270 6 TWIG twig NN cord-005646-xhx9pzhj 3270 7 scorn scorn NN cord-005646-xhx9pzhj 3270 8 , , , cord-005646-xhx9pzhj 3270 9 the the DT cord-005646-xhx9pzhj 3270 10 average average NN cord-005646-xhx9pzhj 3270 11 for for IN cord-005646-xhx9pzhj 3270 12 adequately adequately RB cord-005646-xhx9pzhj 3270 13 sedated sedate VBN cord-005646-xhx9pzhj 3270 14 , , , cord-005646-xhx9pzhj 3270 15 inadequately inadequately RB cord-005646-xhx9pzhj 3270 16 sedated sedate VBN cord-005646-xhx9pzhj 3270 17 , , , cord-005646-xhx9pzhj 3270 18 and and CC cord-005646-xhx9pzhj 3270 19 too too RB cord-005646-xhx9pzhj 3270 20 sedated sedated JJ cord-005646-xhx9pzhj 3270 21 was be VBD cord-005646-xhx9pzhj 3270 22 16.35 16.35 CD cord-005646-xhx9pzhj 3270 23 : : : cord-005646-xhx9pzhj 3270 24 k-'0.77 k-'0.77 NNP cord-005646-xhx9pzhj 3270 25 , , , cord-005646-xhx9pzhj 3270 26 20.85-&L57 20.85-&l57 CD cord-005646-xhx9pzhj 3270 27 , , , cord-005646-xhx9pzhj 3270 28 and and CC cord-005646-xhx9pzhj 3270 29 13.0L-0.89 13.0l-0.89 CD cord-005646-xhx9pzhj 3270 30 , , , cord-005646-xhx9pzhj 3270 31 respectively respectively RB cord-005646-xhx9pzhj 3270 32 . . . cord-005646-xhx9pzhj 3271 1 Conclnsion Conclnsion NNP cord-005646-xhx9pzhj 3271 2 : : : cord-005646-xhx9pzhj 3271 3 in in IN cord-005646-xhx9pzhj 3271 4 our -PRON- PRP$ cord-005646-xhx9pzhj 3271 5 study study NN cord-005646-xhx9pzhj 3271 6 there there EX cord-005646-xhx9pzhj 3271 7 were be VBD cord-005646-xhx9pzhj 3271 8 no no DT cord-005646-xhx9pzhj 3271 9 significantly significantly RB cord-005646-xhx9pzhj 3271 10 statistical statistical JJ cord-005646-xhx9pzhj 3271 11 difference difference NN cord-005646-xhx9pzhj 3271 12 when when WRB cord-005646-xhx9pzhj 3271 13 you -PRON- PRP cord-005646-xhx9pzhj 3271 14 apply apply VBP cord-005646-xhx9pzhj 3271 15 a a DT cord-005646-xhx9pzhj 3271 16 more more RBR cord-005646-xhx9pzhj 3271 17 complex complex JJ cord-005646-xhx9pzhj 3271 18 scale scale NN cord-005646-xhx9pzhj 3271 19 ( ( -LRB- cord-005646-xhx9pzhj 3271 20 CONff'ORT CONff'ORT NNP cord-005646-xhx9pzhj 3271 21 ) ) -RRB- cord-005646-xhx9pzhj 3271 22 or or CC cord-005646-xhx9pzhj 3271 23 a a DT cord-005646-xhx9pzhj 3271 24 less less RBR cord-005646-xhx9pzhj 3271 25 complex complex JJ cord-005646-xhx9pzhj 3271 26 scale scale NN cord-005646-xhx9pzhj 3271 27 ( ( -LRB- cord-005646-xhx9pzhj 3271 28 HARTWIG HARTWIG NNP cord-005646-xhx9pzhj 3271 29 ) ) -RRB- cord-005646-xhx9pzhj 3271 30 to to TO cord-005646-xhx9pzhj 3271 31 assess assess VB cord-005646-xhx9pzhj 3271 32 the the DT cord-005646-xhx9pzhj 3271 33 sedation sedation NN cord-005646-xhx9pzhj 3271 34 of of IN cord-005646-xhx9pzhj 3271 35 mechanically mechanically RB cord-005646-xhx9pzhj 3271 36 vemilated vemilate VBN cord-005646-xhx9pzhj 3271 37 pediatric pediatric JJ cord-005646-xhx9pzhj 3271 38 patients patient NNS cord-005646-xhx9pzhj 3271 39 . . . cord-005646-xhx9pzhj 3271 40 _SP cord-005646-xhx9pzhj 3272 1 The the DT cord-005646-xhx9pzhj 3272 2 application application NN cord-005646-xhx9pzhj 3272 3 of of IN cord-005646-xhx9pzhj 3272 4 local local JJ cord-005646-xhx9pzhj 3272 5 and and CC cord-005646-xhx9pzhj 3272 6 intravenous intravenous JJ cord-005646-xhx9pzhj 3272 7 morphine morphine NN cord-005646-xhx9pzhj 3272 8 infusion infusion NN cord-005646-xhx9pzhj 3272 9 after after IN cord-005646-xhx9pzhj 3272 10 surgery surgery NN cord-005646-xhx9pzhj 3272 11 of of IN cord-005646-xhx9pzhj 3272 12 urinary urinary JJ cord-005646-xhx9pzhj 3272 13 tract tract NN cord-005646-xhx9pzhj 3272 14 Eva Eva NNP cord-005646-xhx9pzhj 3272 15 Nemeth Nemeth NNP cord-005646-xhx9pzhj 3272 16 , , , cord-005646-xhx9pzhj 3272 17 M.D. M.D. NNP cord-005646-xhx9pzhj 3272 18 Semmelweis Semmelweis NNP cord-005646-xhx9pzhj 3272 19 Medical Medical NNP cord-005646-xhx9pzhj 3272 20 University University NNP cord-005646-xhx9pzhj 3272 21 , , , cord-005646-xhx9pzhj 3272 22 First First NNP cord-005646-xhx9pzhj 3272 23 Oepartment Oepartment NNP cord-005646-xhx9pzhj 3272 24 of of IN cord-005646-xhx9pzhj 3272 25 Paediatrics Paediatrics NNP cord-005646-xhx9pzhj 3272 26 , , , cord-005646-xhx9pzhj 3272 27 Budapest Budapest NNP cord-005646-xhx9pzhj 3272 28 , , , cord-005646-xhx9pzhj 3272 29 Hungary Hungary NNP cord-005646-xhx9pzhj 3272 30 In±roduction In±roduction NNP cord-005646-xhx9pzhj 3272 31 : : : cord-005646-xhx9pzhj 3273 1 Continuous continuous JJ cord-005646-xhx9pzhj 3273 2 analgesia analgesia NN cord-005646-xhx9pzhj 3273 3 with with IN cord-005646-xhx9pzhj 3273 4 morphine morphine NN cord-005646-xhx9pzhj 3273 5 may may MD cord-005646-xhx9pzhj 3273 6 be be VB cord-005646-xhx9pzhj 3273 7 ~egarOed ~egarOed NNP cord-005646-xhx9pzhj 3273 8 as as IN cord-005646-xhx9pzhj 3273 9 a a DT cord-005646-xhx9pzhj 3273 10 safe safe JJ cord-005646-xhx9pzhj 3273 11 and and CC cord-005646-xhx9pzhj 3273 12 effective effective JJ cord-005646-xhx9pzhj 3273 13 method method NN cord-005646-xhx9pzhj 3273 14 of of IN cord-005646-xhx9pzhj 3273 15 pain pain NN cord-005646-xhx9pzhj 3273 16 relief relief NN cord-005646-xhx9pzhj 3273 17 during during IN cord-005646-xhx9pzhj 3273 18 postoperative postoperative JJ cord-005646-xhx9pzhj 3273 19 period period NN cord-005646-xhx9pzhj 3273 20 . . . cord-005646-xhx9pzhj 3274 1 Subjects subject NNS cord-005646-xhx9pzhj 3274 2 and and CC cord-005646-xhx9pzhj 3274 3 methods method NNS cord-005646-xhx9pzhj 3274 4 : : : cord-005646-xhx9pzhj 3274 5 24 24 CD cord-005646-xhx9pzhj 3274 6 children child NNS cord-005646-xhx9pzhj 3274 7 /mean /mean . cord-005646-xhx9pzhj 3274 8 age age NN cord-005646-xhx9pzhj 3274 9 2.3 2.3 CD cord-005646-xhx9pzhj 3274 10 years/ years/ CD cord-005646-xhx9pzhj 3274 11 underwent undergo VBD cord-005646-xhx9pzhj 3274 12 elective elective JJ cord-005646-xhx9pzhj 3274 13 ureteroneoimplanta±ion ureteroneoimplanta±ion NNP cord-005646-xhx9pzhj 3274 14 were be VBD cord-005646-xhx9pzhj 3274 15 randomly randomly RB cord-005646-xhx9pzhj 3274 16 selected select VBN cord-005646-xhx9pzhj 3274 17 to to TO cord-005646-xhx9pzhj 3274 18 receive receive VB cord-005646-xhx9pzhj 3274 19 either either CC cord-005646-xhx9pzhj 3274 20 morphin morphin NNP cord-005646-xhx9pzhj 3274 21 intravenously intravenously RB cord-005646-xhx9pzhj 3274 22 of of IN cord-005646-xhx9pzhj 3275 1 lo lo NNP cord-005646-xhx9pzhj 3275 2 ug ug NNP cord-005646-xhx9pzhj 3275 3 / / SYM cord-005646-xhx9pzhj 3275 4 kg kg NNP cord-005646-xhx9pzhj 3275 5 / / SYM cord-005646-xhx9pzhj 3275 6 h h NN cord-005646-xhx9pzhj 3275 7 /Group /Group . cord-005646-xhx9pzhj 3276 1 One/ One/ NNS cord-005646-xhx9pzhj 3276 2 or or CC cord-005646-xhx9pzhj 3276 3 bladder bladder NN cord-005646-xhx9pzhj 3276 4 morphineinfusion morphineinfusion NN cord-005646-xhx9pzhj 3277 1 50 50 CD cord-005646-xhx9pzhj 3278 1 ug ug NNP cord-005646-xhx9pzhj 3278 2 / / SYM cord-005646-xhx9pzhj 3278 3 kg kg NNP cord-005646-xhx9pzhj 3278 4 / / SYM cord-005646-xhx9pzhj 3278 5 h h NN cord-005646-xhx9pzhj 3278 6 /Group /Group . cord-005646-xhx9pzhj 3279 1 Two/ Two/ VBN cord-005646-xhx9pzhj 3279 2 after after IN cord-005646-xhx9pzhj 3279 3 surgery surgery NN cord-005646-xhx9pzhj 3279 4 . . . cord-005646-xhx9pzhj 3280 1 All all DT cord-005646-xhx9pzhj 3280 2 patients patient NNS cord-005646-xhx9pzhj 3280 3 were be VBD cord-005646-xhx9pzhj 3280 4 prospectively prospectively RB cord-005646-xhx9pzhj 3280 5 evaluated evaluate VBN cord-005646-xhx9pzhj 3280 6 during during IN cord-005646-xhx9pzhj 3280 7 their -PRON- PRP$ cord-005646-xhx9pzhj 3280 8 s±ay s±ay NNS cord-005646-xhx9pzhj 3280 9 in in IN cord-005646-xhx9pzhj 3280 10 the the DT cord-005646-xhx9pzhj 3280 11 postanaesthetic postanaesthetic JJ cord-005646-xhx9pzhj 3280 12 care care NN cord-005646-xhx9pzhj 3280 13 unit unit NN cord-005646-xhx9pzhj 3280 14 . . . cord-005646-xhx9pzhj 3281 1 Cardiac Cardiac NNP cord-005646-xhx9pzhj 3281 2 and and CC cord-005646-xhx9pzhj 3281 3 respirafory respirafory JJ cord-005646-xhx9pzhj 3281 4 rates rate NNS cord-005646-xhx9pzhj 3281 5 , , , cord-005646-xhx9pzhj 3281 6 blood blood NN cord-005646-xhx9pzhj 3281 7 pressure pressure NN cord-005646-xhx9pzhj 3281 8 , , , cord-005646-xhx9pzhj 3281 9 Sa Sa NNP cord-005646-xhx9pzhj 3281 10 02 02 CD cord-005646-xhx9pzhj 3281 11 ~,degree ~,degree NN cord-005646-xhx9pzhj 3281 12 of of IN cord-005646-xhx9pzhj 3281 13 alertness alertness NN cord-005646-xhx9pzhj 3281 14 , , , cord-005646-xhx9pzhj 3281 15 pain pain NN cord-005646-xhx9pzhj 3281 16 perception perception NN cord-005646-xhx9pzhj 3281 17 and and CC cord-005646-xhx9pzhj 3281 18 complaints complaint NNS cord-005646-xhx9pzhj 3281 19 of of IN cord-005646-xhx9pzhj 3281 20 the the DT cord-005646-xhx9pzhj 3281 21 paticnto paticnto NNP cord-005646-xhx9pzhj 3281 22 ~cr~ ~cr~ NNP cord-005646-xhx9pzhj 3281 23 recorded record VBD cord-005646-xhx9pzhj 3281 24 hourly hourly RB cord-005646-xhx9pzhj 3281 25 . . . cord-005646-xhx9pzhj 3282 1 Pruritus Pruritus NNP cord-005646-xhx9pzhj 3282 2 , , , cord-005646-xhx9pzhj 3282 3 nausea nausea NN cord-005646-xhx9pzhj 3282 4 and and CC cord-005646-xhx9pzhj 3282 5 vomiting vomiting NN cord-005646-xhx9pzhj 3282 6 , , , cord-005646-xhx9pzhj 3282 7 voiding void VBG cord-005646-xhx9pzhj 3282 8 difficul-±ies difficul-±ies NN cord-005646-xhx9pzhj 3282 9 , , , cord-005646-xhx9pzhj 3282 10 sedation sedation NN cord-005646-xhx9pzhj 3282 11 , , , cord-005646-xhx9pzhj 3282 12 dysphoria dysphoria NN cord-005646-xhx9pzhj 3282 13 were be VBD cord-005646-xhx9pzhj 3282 14 systematically systematically RB cord-005646-xhx9pzhj 3282 15 sough sough VBN cord-005646-xhx9pzhj 3282 16 and and CC cord-005646-xhx9pzhj 3282 17 quoted quote VBN cord-005646-xhx9pzhj 3282 18 . . . cord-005646-xhx9pzhj 3283 1 Statistical statistical JJ cord-005646-xhx9pzhj 3283 2 analysis analysis NN cord-005646-xhx9pzhj 3283 3 was be VBD cord-005646-xhx9pzhj 3283 4 performed perform VBN cord-005646-xhx9pzhj 3283 5 by by IN cord-005646-xhx9pzhj 3283 6 chi chi NNP cord-005646-xhx9pzhj 3283 7 square square NNP cord-005646-xhx9pzhj 3283 8 test test NN cord-005646-xhx9pzhj 3283 9 . . . cord-005646-xhx9pzhj 3284 1 Results result NNS cord-005646-xhx9pzhj 3284 2 : : : cord-005646-xhx9pzhj 3285 1 Postoperative postoperative JJ cord-005646-xhx9pzhj 3285 2 analgesia analgesia NN cord-005646-xhx9pzhj 3285 3 was be VBD cord-005646-xhx9pzhj 3285 4 the the DT cord-005646-xhx9pzhj 3285 5 same same JJ cord-005646-xhx9pzhj 3285 6 in in IN cord-005646-xhx9pzhj 3285 7 the the DT cord-005646-xhx9pzhj 3285 8 two two CD cord-005646-xhx9pzhj 3285 9 groups group NNS cord-005646-xhx9pzhj 3285 10 , , , cord-005646-xhx9pzhj 3285 11 but but CC cord-005646-xhx9pzhj 3285 12 side side NN cord-005646-xhx9pzhj 3285 13 effects effect NNS cord-005646-xhx9pzhj 3285 14 were be VBD cord-005646-xhx9pzhj 3285 15 less less JJR cord-005646-xhx9pzhj 3285 16 in in IN cord-005646-xhx9pzhj 3285 17 the the DT cord-005646-xhx9pzhj 3285 18 bladder bladder NN cord-005646-xhx9pzhj 3285 19 morphine morphine NN cord-005646-xhx9pzhj 3285 20 group group NN cord-005646-xhx9pzhj 3285 21 , , , cord-005646-xhx9pzhj 3285 22 because because IN cord-005646-xhx9pzhj 3285 23 of of IN cord-005646-xhx9pzhj 3285 24 the the DT cord-005646-xhx9pzhj 3285 25 lower low JJR cord-005646-xhx9pzhj 3285 26 Se Se NNP cord-005646-xhx9pzhj 3285 27 morphine morphine NN cord-005646-xhx9pzhj 3285 28 concentration concentration NN cord-005646-xhx9pzhj 3285 29 . . . cord-005646-xhx9pzhj 3286 1 The the DT cord-005646-xhx9pzhj 3286 2 differentes differente NNS cord-005646-xhx9pzhj 3286 3 were be VBD cord-005646-xhx9pzhj 3286 4 n't not RB cord-005646-xhx9pzhj 3286 5 significant significant JJ cord-005646-xhx9pzhj 3286 6 in in IN cord-005646-xhx9pzhj 3286 7 two two CD cord-005646-xhx9pzhj 3286 8 groups group NNS cord-005646-xhx9pzhj 3286 9 . . . cord-005646-xhx9pzhj 3287 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3287 2 : : : cord-005646-xhx9pzhj 3288 1 The the DT cord-005646-xhx9pzhj 3288 2 administration administration NN cord-005646-xhx9pzhj 3288 3 of of IN cord-005646-xhx9pzhj 3288 4 bladder bladder NN cord-005646-xhx9pzhj 3288 5 morphine morphine NN cord-005646-xhx9pzhj 3288 6 infusion infusion NN cord-005646-xhx9pzhj 3288 7 is be VBZ cord-005646-xhx9pzhj 3288 8 a a DT cord-005646-xhx9pzhj 3288 9 safe safe JJ cord-005646-xhx9pzhj 3288 10 and and CC cord-005646-xhx9pzhj 3288 11 effective effective JJ cord-005646-xhx9pzhj 3288 12 method method NN cord-005646-xhx9pzhj 3288 13 in in IN cord-005646-xhx9pzhj 3288 14 children child NNS cord-005646-xhx9pzhj 3288 15 . . . cord-005646-xhx9pzhj 3289 1 Objetive Objetive NNP cord-005646-xhx9pzhj 3290 1 : : : cord-005646-xhx9pzhj 3290 2 compare compare VB cord-005646-xhx9pzhj 3290 3 the the DT cord-005646-xhx9pzhj 3290 4 evaluations evaluation NNS cord-005646-xhx9pzhj 3290 5 of of IN cord-005646-xhx9pzhj 3290 6 sedation sedation NN cord-005646-xhx9pzhj 3290 7 level level NN cord-005646-xhx9pzhj 3290 8 made make VBN cord-005646-xhx9pzhj 3290 9 by by IN cord-005646-xhx9pzhj 3290 10 physicians physician NNS cord-005646-xhx9pzhj 3290 11 and and CC cord-005646-xhx9pzhj 3290 12 nurses nurse NNS cord-005646-xhx9pzhj 3290 13 with with IN cord-005646-xhx9pzhj 3290 14 the the DT cord-005646-xhx9pzhj 3290 15 Visual Visual NNP cord-005646-xhx9pzhj 3290 16 Analog Analog NNP cord-005646-xhx9pzhj 3290 17 Scale Scale NNP cord-005646-xhx9pzhj 3290 18 ( ( -LRB- cord-005646-xhx9pzhj 3290 19 VAS VAS NNP cord-005646-xhx9pzhj 3290 20 ) ) -RRB- cord-005646-xhx9pzhj 3290 21 and and CC cord-005646-xhx9pzhj 3290 22 the the DT cord-005646-xhx9pzhj 3290 23 COMFORT COMFORT NNP cord-005646-xhx9pzhj 3290 24 Scale Scale NNP cord-005646-xhx9pzhj 3290 25 ( ( -LRB- cord-005646-xhx9pzhj 3290 26 CS CS NNP cord-005646-xhx9pzhj 3290 27 ) ) -RRB- cord-005646-xhx9pzhj 3290 28 in in IN cord-005646-xhx9pzhj 3290 29 pediatrics pediatric NNS cord-005646-xhx9pzhj 3290 30 patients patient NNS cord-005646-xhx9pzhj 3290 31 receiving receive VBG cord-005646-xhx9pzhj 3290 32 difforents difforent NNS cord-005646-xhx9pzhj 3290 33 modes mode NNS cord-005646-xhx9pzhj 3290 34 of of IN cord-005646-xhx9pzhj 3290 35 intravenous intravenous JJ cord-005646-xhx9pzhj 3290 36 sedation sedation NN cord-005646-xhx9pzhj 3290 37 . . . cord-005646-xhx9pzhj 3291 1 Material material NN cord-005646-xhx9pzhj 3291 2 ~ ~ NFP cord-005646-xhx9pzhj 3291 3 Method method NN cord-005646-xhx9pzhj 3291 4 . . . cord-005646-xhx9pzhj 3291 5 " " '' cord-005646-xhx9pzhj 3292 1 file file NN cord-005646-xhx9pzhj 3292 2 evaluations evaluation NNS cord-005646-xhx9pzhj 3292 3 were be VBD cord-005646-xhx9pzhj 3292 4 made make VBN cord-005646-xhx9pzhj 3292 5 by by IN cord-005646-xhx9pzhj 3292 6 an an DT cord-005646-xhx9pzhj 3292 7 attending attend VBG cord-005646-xhx9pzhj 3292 8 physician physician NN cord-005646-xhx9pzhj 3292 9 and and CC cord-005646-xhx9pzhj 3292 10 nurse nurse NN cord-005646-xhx9pzhj 3292 11 with with IN cord-005646-xhx9pzhj 3292 12 the the DT cord-005646-xhx9pzhj 3292 13 VAS VAS NNP cord-005646-xhx9pzhj 3292 14 and and CC cord-005646-xhx9pzhj 3292 15 by by IN cord-005646-xhx9pzhj 3292 16 another another DT cord-005646-xhx9pzhj 3292 17 physician physician NN cord-005646-xhx9pzhj 3292 18 ( ( -LRB- cord-005646-xhx9pzhj 3292 19 always always RB cord-005646-xhx9pzhj 3292 20 the the DT cord-005646-xhx9pzhj 3292 21 same same JJ cord-005646-xhx9pzhj 3292 22 ) ) -RRB- cord-005646-xhx9pzhj 3292 23 using use VBG cord-005646-xhx9pzhj 3292 24 the the DT cord-005646-xhx9pzhj 3292 25 CS CS NNP cord-005646-xhx9pzhj 3292 26 . . . cord-005646-xhx9pzhj 3293 1 The the DT cord-005646-xhx9pzhj 3293 2 observations observation NNS cord-005646-xhx9pzhj 3293 3 were be VBD cord-005646-xhx9pzhj 3293 4 divided divide VBN cord-005646-xhx9pzhj 3293 5 following follow VBG cord-005646-xhx9pzhj 3293 6 the the DT cord-005646-xhx9pzhj 3293 7 sedation sedation NN cord-005646-xhx9pzhj 3293 8 mode mode NN cord-005646-xhx9pzhj 3293 9 : : : cord-005646-xhx9pzhj 3293 10 one one CD cord-005646-xhx9pzhj 3293 11 drug drug NN cord-005646-xhx9pzhj 3293 12 ( ( -LRB- cord-005646-xhx9pzhj 3293 13 Fentanyl Fentanyl NNP cord-005646-xhx9pzhj 3293 14 or or CC cord-005646-xhx9pzhj 3293 15 Midazolan Midazolan NNP cord-005646-xhx9pzhj 3293 16 ) ) -RRB- cord-005646-xhx9pzhj 3293 17 , , , cord-005646-xhx9pzhj 3293 18 two two CD cord-005646-xhx9pzhj 3293 19 continuous continuous JJ cord-005646-xhx9pzhj 3293 20 drugs drug NNS cord-005646-xhx9pzhj 3293 21 , , , cord-005646-xhx9pzhj 3293 22 one one CD cord-005646-xhx9pzhj 3293 23 continuous continuous JJ cord-005646-xhx9pzhj 3293 24 and and CC cord-005646-xhx9pzhj 3293 25 one one CD cord-005646-xhx9pzhj 3293 26 intermi intermi NN cord-005646-xhx9pzhj 3293 27 ~ ~ NFP cord-005646-xhx9pzhj 3293 28 ent ent NNP cord-005646-xhx9pzhj 3293 29 drug drug NNP cord-005646-xhx9pzhj 3293 30 and and CC cord-005646-xhx9pzhj 3293 31 two two CD cord-005646-xhx9pzhj 3293 32 intermittent intermittent JJ cord-005646-xhx9pzhj 3293 33 drug drug NN cord-005646-xhx9pzhj 3293 34 ( ( -LRB- cord-005646-xhx9pzhj 3293 35 Fentanyl Fentanyl NNP cord-005646-xhx9pzhj 3293 36 and and CC cord-005646-xhx9pzhj 3293 37 Midazolan Midazolan NNP cord-005646-xhx9pzhj 3293 38 ) ) -RRB- cord-005646-xhx9pzhj 3293 39 . . . cord-005646-xhx9pzhj 3294 1 The the DT cord-005646-xhx9pzhj 3294 2 groups group NNS cord-005646-xhx9pzhj 3294 3 were be VBD cord-005646-xhx9pzhj 3294 4 compared compare VBN cord-005646-xhx9pzhj 3294 5 using use VBG cord-005646-xhx9pzhj 3294 6 the the DT cord-005646-xhx9pzhj 3294 7 t t NNP cord-005646-xhx9pzhj 3294 8 - - HYPH cord-005646-xhx9pzhj 3294 9 Student Student NNP cord-005646-xhx9pzhj 3294 10 test test NN cord-005646-xhx9pzhj 3294 11 . . . cord-005646-xhx9pzhj 3295 1 The the DT cord-005646-xhx9pzhj 3295 2 groups group NNS cord-005646-xhx9pzhj 3295 3 also also RB cord-005646-xhx9pzhj 3295 4 were be VBD cord-005646-xhx9pzhj 3295 5 compared compare VBN cord-005646-xhx9pzhj 3295 6 between between IN cord-005646-xhx9pzhj 3295 7 the the DT cord-005646-xhx9pzhj 3295 8 percentual percentual NN cord-005646-xhx9pzhj 3295 9 of of IN cord-005646-xhx9pzhj 3295 10 agreement agreement NN cord-005646-xhx9pzhj 3295 11 of of IN cord-005646-xhx9pzhj 3295 12 the the DT cord-005646-xhx9pzhj 3295 13 evaluations evaluation NNS cord-005646-xhx9pzhj 3295 14 of of IN cord-005646-xhx9pzhj 3295 15 sedation sedation NN cord-005646-xhx9pzhj 3295 16 level level NN cord-005646-xhx9pzhj 3295 17 made make VBN cord-005646-xhx9pzhj 3295 18 by by IN cord-005646-xhx9pzhj 3295 19 physicians physician NNS cord-005646-xhx9pzhj 3295 20 and and CC cord-005646-xhx9pzhj 3295 21 nurses nurse NNS cord-005646-xhx9pzhj 3295 22 with with IN cord-005646-xhx9pzhj 3295 23 the the DT cord-005646-xhx9pzhj 3295 24 CS CS NNP cord-005646-xhx9pzhj 3295 25 and and CC cord-005646-xhx9pzhj 3295 26 VAS VAS NNP cord-005646-xhx9pzhj 3295 27 using use VBG cord-005646-xhx9pzhj 3295 28 the the DT cord-005646-xhx9pzhj 3295 29 X x NN cord-005646-xhx9pzhj 3295 30 2 2 CD cord-005646-xhx9pzhj 3295 31 . . . cord-005646-xhx9pzhj 3296 1 Results result NNS cord-005646-xhx9pzhj 3296 2 : : : cord-005646-xhx9pzhj 3297 1 we -PRON- PRP cord-005646-xhx9pzhj 3297 2 didnk didnk NNS cord-005646-xhx9pzhj 3297 3 find find VBP cord-005646-xhx9pzhj 3297 4 any any DT cord-005646-xhx9pzhj 3297 5 statistical statistical JJ cord-005646-xhx9pzhj 3297 6 difference difference NN cord-005646-xhx9pzhj 3297 7 between between IN cord-005646-xhx9pzhj 3297 8 the the DT cord-005646-xhx9pzhj 3297 9 observations observation NNS cord-005646-xhx9pzhj 3297 10 made make VBN cord-005646-xhx9pzhj 3297 11 by by IN cord-005646-xhx9pzhj 3297 12 physicians physician NNS cord-005646-xhx9pzhj 3297 13 and and CC cord-005646-xhx9pzhj 3297 14 nurses nurse NNS cord-005646-xhx9pzhj 3297 15 with with IN cord-005646-xhx9pzhj 3297 16 the the DT cord-005646-xhx9pzhj 3297 17 VAS VAS NNP cord-005646-xhx9pzhj 3297 18 in in IN cord-005646-xhx9pzhj 3297 19 the the DT cord-005646-xhx9pzhj 3297 20 differmts differmts NNP cord-005646-xhx9pzhj 3297 21 modes mode NNS cord-005646-xhx9pzhj 3297 22 of of IN cord-005646-xhx9pzhj 3297 23 intravenous intravenous JJ cord-005646-xhx9pzhj 3297 24 sedation sedation NN cord-005646-xhx9pzhj 3297 25 , , , cord-005646-xhx9pzhj 3297 26 The the DT cord-005646-xhx9pzhj 3297 27 average average NN cord-005646-xhx9pzhj 3297 28 of of IN cord-005646-xhx9pzhj 3297 29 the the DT cord-005646-xhx9pzhj 3297 30 observations observation NNS cord-005646-xhx9pzhj 3297 31 using use VBG cord-005646-xhx9pzhj 3297 32 the the DT cord-005646-xhx9pzhj 3297 33 CS CS NNP cord-005646-xhx9pzhj 3297 34 betwom betwom RB cord-005646-xhx9pzhj 3297 35 one one CD cord-005646-xhx9pzhj 3297 36 drug drug NN cord-005646-xhx9pzhj 3297 37 and and CC cord-005646-xhx9pzhj 3297 38 two two CD cord-005646-xhx9pzhj 3297 39 drugs drug NNS cord-005646-xhx9pzhj 3297 40 modes modes NNPS cord-005646-xhx9pzhj 3297 41 didnk didnk NNP cord-005646-xhx9pzhj 3297 42 exhibit exhibit VBP cord-005646-xhx9pzhj 3297 43 also also RB cord-005646-xhx9pzhj 3297 44 statistical statistical JJ cord-005646-xhx9pzhj 3297 45 difference difference NN cord-005646-xhx9pzhj 3297 46 . . . cord-005646-xhx9pzhj 3298 1 The the DT cord-005646-xhx9pzhj 3298 2 observations observation NNS cord-005646-xhx9pzhj 3298 3 made make VBN cord-005646-xhx9pzhj 3298 4 by by IN cord-005646-xhx9pzhj 3298 5 physicians physician NNS cord-005646-xhx9pzhj 3298 6 mad mad JJ cord-005646-xhx9pzhj 3298 7 nurses nurse NNS cord-005646-xhx9pzhj 3298 8 using use VBG cord-005646-xhx9pzhj 3298 9 the the DT cord-005646-xhx9pzhj 3298 10 the the DT cord-005646-xhx9pzhj 3298 11 VAS VAS NNP cord-005646-xhx9pzhj 3298 12 when when WRB cord-005646-xhx9pzhj 3298 13 compared compare VBN cord-005646-xhx9pzhj 3298 14 with with IN cord-005646-xhx9pzhj 3298 15 the the DT cord-005646-xhx9pzhj 3298 16 CS CS NNP cord-005646-xhx9pzhj 3298 17 did do VBD cord-005646-xhx9pzhj 3298 18 n't not RB cord-005646-xhx9pzhj 3298 19 show show VB cord-005646-xhx9pzhj 3298 20 statistical statistical JJ cord-005646-xhx9pzhj 3298 21 difference difference NN cord-005646-xhx9pzhj 3298 22 between between IN cord-005646-xhx9pzhj 3298 23 the the DT cord-005646-xhx9pzhj 3298 24 sedation sedation NN cord-005646-xhx9pzhj 3298 25 level level NN cord-005646-xhx9pzhj 3298 26 . . . cord-005646-xhx9pzhj 3299 1 We -PRON- PRP cord-005646-xhx9pzhj 3299 2 found find VBD cord-005646-xhx9pzhj 3299 3 statistical statistical JJ cord-005646-xhx9pzhj 3299 4 difference difference NN cord-005646-xhx9pzhj 3299 5 only only RB cord-005646-xhx9pzhj 3299 6 in in IN cord-005646-xhx9pzhj 3299 7 percentual percentual NN cord-005646-xhx9pzhj 3299 8 of of IN cord-005646-xhx9pzhj 3299 9 concordance concordance NN cord-005646-xhx9pzhj 3299 10 of of IN cord-005646-xhx9pzhj 3299 11 sedation sedation NN cord-005646-xhx9pzhj 3299 12 level level NN cord-005646-xhx9pzhj 3299 13 between between IN cord-005646-xhx9pzhj 3299 14 physicians physician NNS cord-005646-xhx9pzhj 3299 15 and and CC cord-005646-xhx9pzhj 3299 16 nurses nurse NNS cord-005646-xhx9pzhj 3299 17 when when WRB cord-005646-xhx9pzhj 3299 18 compared compare VBD cord-005646-xhx9pzhj 3299 19 the the DT cord-005646-xhx9pzhj 3299 20 one one CD cord-005646-xhx9pzhj 3299 21 and and CC cord-005646-xhx9pzhj 3299 22 two two CD cord-005646-xhx9pzhj 3299 23 drugs drug NNS cord-005646-xhx9pzhj 3299 24 modes mode NNS cord-005646-xhx9pzhj 3299 25 of of IN cord-005646-xhx9pzhj 3299 26 sedation sedation NN cord-005646-xhx9pzhj 3299 27 . . . cord-005646-xhx9pzhj 3300 1 Conclusion conclusion NN cord-005646-xhx9pzhj 3300 2 : : : cord-005646-xhx9pzhj 3300 3 we -PRON- PRP cord-005646-xhx9pzhj 3300 4 did do VBD cord-005646-xhx9pzhj 3300 5 n't not RB cord-005646-xhx9pzhj 3300 6 find find VB cord-005646-xhx9pzhj 3300 7 differences difference NNS cord-005646-xhx9pzhj 3300 8 in in IN cord-005646-xhx9pzhj 3300 9 the the DT cord-005646-xhx9pzhj 3300 10 observations observation NNS cord-005646-xhx9pzhj 3300 11 made make VBN cord-005646-xhx9pzhj 3300 12 by by IN cord-005646-xhx9pzhj 3300 13 physicians physician NNS cord-005646-xhx9pzhj 3300 14 and and CC cord-005646-xhx9pzhj 3300 15 nurses nurse NNS cord-005646-xhx9pzhj 3300 16 in in IN cord-005646-xhx9pzhj 3300 17 the the DT cord-005646-xhx9pzhj 3300 18 sedation sedation NN cord-005646-xhx9pzhj 3300 19 level level NN cord-005646-xhx9pzhj 3300 20 , , , cord-005646-xhx9pzhj 3300 21 only only RB cord-005646-xhx9pzhj 3300 22 in in IN cord-005646-xhx9pzhj 3300 23 concordance concordance NN cord-005646-xhx9pzhj 3300 24 pereentua/ pereentua/ CD cord-005646-xhx9pzhj 3300 25 of of IN cord-005646-xhx9pzhj 3300 26 observations observation NNS cord-005646-xhx9pzhj 3300 27 when when WRB cord-005646-xhx9pzhj 3300 28 compared compare VBN cord-005646-xhx9pzhj 3300 29 two two CD cord-005646-xhx9pzhj 3300 30 modes mode NNS cord-005646-xhx9pzhj 3300 31 of of IN cord-005646-xhx9pzhj 3300 32 sedation sedation NN cord-005646-xhx9pzhj 3300 33 . . . cord-005646-xhx9pzhj 3301 1 The the DT cord-005646-xhx9pzhj 3301 2 observations observation NNS cord-005646-xhx9pzhj 3301 3 using use VBG cord-005646-xhx9pzhj 3301 4 the the DT cord-005646-xhx9pzhj 3301 5 CS CS NNP cord-005646-xhx9pzhj 3301 6 ( ( -LRB- cord-005646-xhx9pzhj 3301 7 more more RBR cord-005646-xhx9pzhj 3301 8 complex complex JJ cord-005646-xhx9pzhj 3301 9 ) ) -RRB- cord-005646-xhx9pzhj 3301 10 didnk didnk NNS cord-005646-xhx9pzhj 3301 11 show show VBP cord-005646-xhx9pzhj 3301 12 differences difference NNS cord-005646-xhx9pzhj 3301 13 when when WRB cord-005646-xhx9pzhj 3301 14 compared compare VBN cord-005646-xhx9pzhj 3301 15 with with IN cord-005646-xhx9pzhj 3301 16 the the DT cord-005646-xhx9pzhj 3301 17 VAS VAS NNP cord-005646-xhx9pzhj 3301 18 . . . cord-005646-xhx9pzhj 3302 1 Effects effect NNS cord-005646-xhx9pzhj 3302 2 of of IN cord-005646-xhx9pzhj 3302 3 age age NN cord-005646-xhx9pzhj 3302 4 , , , cord-005646-xhx9pzhj 3302 5 concurrent concurrent JJ cord-005646-xhx9pzhj 3302 6 administration administration NN cord-005646-xhx9pzhj 3302 7 of of IN cord-005646-xhx9pzhj 3302 8 other other JJ cord-005646-xhx9pzhj 3302 9 pharmacologic pharmacologic JJ cord-005646-xhx9pzhj 3302 10 agents agent NNS cord-005646-xhx9pzhj 3302 11 , , , cord-005646-xhx9pzhj 3302 12 and and CC cord-005646-xhx9pzhj 3302 13 disease disease NN cord-005646-xhx9pzhj 3302 14 [ [ -LRB- cord-005646-xhx9pzhj 3302 15 cardiac(n=31 cardiac(n=31 NNP cord-005646-xhx9pzhj 3302 16 ) ) -RRB- cord-005646-xhx9pzhj 3302 17 & & CC cord-005646-xhx9pzhj 3302 18 pulmonary(n=22 pulmonary(n=22 NNP cord-005646-xhx9pzhj 3302 19 ) ) -RRB- cord-005646-xhx9pzhj 3302 20 ] ] -RRB- cord-005646-xhx9pzhj 3302 21 on on IN cord-005646-xhx9pzhj 3302 22 the the DT cord-005646-xhx9pzhj 3302 23 PK PK NNP cord-005646-xhx9pzhj 3302 24 & & CC cord-005646-xhx9pzhj 3302 25 PD PD NNP cord-005646-xhx9pzhj 3302 26 of of IN cord-005646-xhx9pzhj 3302 27 B B NNP cord-005646-xhx9pzhj 3302 28 were be VBD cord-005646-xhx9pzhj 3302 29 evaluated evaluate VBN cord-005646-xhx9pzhj 3302 30 in in IN cord-005646-xhx9pzhj 3302 31 volume volume NN cord-005646-xhx9pzhj 3302 32 overloaded overload VBN cord-005646-xhx9pzhj 3302 33 infants infant NNS cord-005646-xhx9pzhj 3302 34 aged age VBN cord-005646-xhx9pzhj 3302 35 4 4 CD cord-005646-xhx9pzhj 3302 36 days-6 days-6 NNP cord-005646-xhx9pzhj 3302 37 mo mo NNP cord-005646-xhx9pzhj 3302 38 ( ( -LRB- cord-005646-xhx9pzhj 3302 39 n=53 n=53 NNP cord-005646-xhx9pzhj 3302 40 ) ) -RRB- cord-005646-xhx9pzhj 3302 41 . . . cord-005646-xhx9pzhj 3303 1 Single single JJ cord-005646-xhx9pzhj 3303 2 doses dose NNS cord-005646-xhx9pzhj 3303 3 of of IN cord-005646-xhx9pzhj 3303 4 0.005,0.01,0.015,0.02,0.025 0.005,0.01,0.015,0.02,0.025 NNP cord-005646-xhx9pzhj 3303 5 , , , cord-005646-xhx9pzhj 3303 6 0,03 0,03 CD cord-005646-xhx9pzhj 3303 7 , , , cord-005646-xhx9pzhj 3303 8 0.035,0.05 0.035,0.05 CD cord-005646-xhx9pzhj 3303 9 & & CC cord-005646-xhx9pzhj 3303 10 0.10 0.10 CD cord-005646-xhx9pzhj 3303 11 mg mg NNP cord-005646-xhx9pzhj 3303 12 / / SYM cord-005646-xhx9pzhj 3303 13 kg kg NNP cord-005646-xhx9pzhj 3303 14 IV IV NNP cord-005646-xhx9pzhj 3303 15 were be VBD cord-005646-xhx9pzhj 3303 16 given give VBN cord-005646-xhx9pzhj 3303 17 over over IN cord-005646-xhx9pzhj 3303 18 1 1 CD cord-005646-xhx9pzhj 3303 19 - - SYM cord-005646-xhx9pzhj 3303 20 2 2 CD cord-005646-xhx9pzhj 3303 21 min min NN cord-005646-xhx9pzhj 3303 22 after after IN cord-005646-xhx9pzhj 3303 23 baseline baseline JJ cord-005646-xhx9pzhj 3303 24 evaluation evaluation NN cord-005646-xhx9pzhj 3303 25 . . . cord-005646-xhx9pzhj 3304 1 Age age NN cord-005646-xhx9pzhj 3304 2 was be VBD cord-005646-xhx9pzhj 3304 3 used use VBN cord-005646-xhx9pzhj 3304 4 as as IN cord-005646-xhx9pzhj 3304 5 a a DT cord-005646-xhx9pzhj 3304 6 continuous continuous JJ cord-005646-xhx9pzhj 3304 7 vadable vadable NN cord-005646-xhx9pzhj 3304 8 to to TO cord-005646-xhx9pzhj 3304 9 determine determine VB cord-005646-xhx9pzhj 3304 10 its -PRON- PRP$ cord-005646-xhx9pzhj 3304 11 effects effect NNS cord-005646-xhx9pzhj 3304 12 on on IN cord-005646-xhx9pzhj 3304 13 the the DT cord-005646-xhx9pzhj 3304 14 variability variability NN cord-005646-xhx9pzhj 3304 15 in in IN cord-005646-xhx9pzhj 3304 16 the the DT cord-005646-xhx9pzhj 3304 17 PK PK NNP cord-005646-xhx9pzhj 3304 18 & & CC cord-005646-xhx9pzhj 3304 19 PD PD NNP cord-005646-xhx9pzhj 3304 20 of of IN cord-005646-xhx9pzhj 3304 21 B. B. NNP cord-005646-xhx9pzhj 3304 22 Values Values NNP cord-005646-xhx9pzhj 3304 23 for for IN cord-005646-xhx9pzhj 3304 24 PK PK NNP cord-005646-xhx9pzhj 3304 25 parameters parameter NNS cord-005646-xhx9pzhj 3304 26 were be VBD cord-005646-xhx9pzhj 3304 27 compared compare VBN cord-005646-xhx9pzhj 3304 28 between between IN cord-005646-xhx9pzhj 3304 29 patients patient NNS cord-005646-xhx9pzhj 3304 30 in in IN cord-005646-xhx9pzhj 3304 31 cardiac cardiac JJ cord-005646-xhx9pzhj 3304 32 and and CC cord-005646-xhx9pzhj 3304 33 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3304 34 disease disease NN cord-005646-xhx9pzhj 3304 35 groups group NNS cord-005646-xhx9pzhj 3304 36 . . . cord-005646-xhx9pzhj 3305 1 Hierarchical hierarchical JJ cord-005646-xhx9pzhj 3305 2 multiple multiple JJ cord-005646-xhx9pzhj 3305 3 regression regression NN cord-005646-xhx9pzhj 3305 4 analyses analysis NNS cord-005646-xhx9pzhj 3305 5 were be VBD cord-005646-xhx9pzhj 3305 6 used use VBN cord-005646-xhx9pzhj 3305 7 to to TO cord-005646-xhx9pzhj 3305 8 determine determine VB cord-005646-xhx9pzhj 3305 9 the the DT cord-005646-xhx9pzhj 3305 10 effects effect NNS cord-005646-xhx9pzhj 3305 11 of of IN cord-005646-xhx9pzhj 3305 12 age age NN cord-005646-xhx9pzhj 3305 13 , , , cord-005646-xhx9pzhj 3305 14 disease disease NN cord-005646-xhx9pzhj 3305 15 and and CC cord-005646-xhx9pzhj 3305 16 other other JJ cord-005646-xhx9pzhj 3305 17 pharmacologic pharmacologic JJ cord-005646-xhx9pzhj 3305 18 agents agent NNS cord-005646-xhx9pzhj 3305 19 on on IN cord-005646-xhx9pzhj 3305 20 the the DT cord-005646-xhx9pzhj 3305 21 variability variability NN cord-005646-xhx9pzhj 3305 22 of of IN cord-005646-xhx9pzhj 3305 23 bumetanide bumetanide NN cord-005646-xhx9pzhj 3305 24 excretion excretion NN cord-005646-xhx9pzhj 3305 25 rate rate NN cord-005646-xhx9pzhj 3305 26 ( ( -LRB- cord-005646-xhx9pzhj 3305 27 BER BER NNP cord-005646-xhx9pzhj 3305 28 ) ) -RRB- cord-005646-xhx9pzhj 3305 29 and and CC cord-005646-xhx9pzhj 3305 30 PD PD NNP cord-005646-xhx9pzhj 3305 31 responses response NNS cord-005646-xhx9pzhj 3305 32 , , , cord-005646-xhx9pzhj 3305 33 e.g. e.g. RB cord-005646-xhx9pzhj 3305 34 urine urine NN cord-005646-xhx9pzhj 3305 35 flow flow NN cord-005646-xhx9pzhj 3305 36 rate rate NN cord-005646-xhx9pzhj 3305 37 ( ( -LRB- cord-005646-xhx9pzhj 3305 38 UFR UFR NNP cord-005646-xhx9pzhj 3305 39 ) ) -RRB- cord-005646-xhx9pzhj 3305 40 & & CC cord-005646-xhx9pzhj 3305 41 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3305 42 excretion excretion NN cord-005646-xhx9pzhj 3305 43 . . . cord-005646-xhx9pzhj 3306 1 CIT CIT NNP cord-005646-xhx9pzhj 3306 2 , , , cord-005646-xhx9pzhj 3306 3 CIR CIR NNP cord-005646-xhx9pzhj 3306 4 & & CC cord-005646-xhx9pzhj 3306 5 CINR CINR NNP cord-005646-xhx9pzhj 3306 6 increased increase VBD cord-005646-xhx9pzhj 3306 7 with with IN cord-005646-xhx9pzhj 3306 8 age age NN cord-005646-xhx9pzhj 3306 9 ( ( -LRB- cord-005646-xhx9pzhj 3306 10 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 3306 11 ) ) -RRB- cord-005646-xhx9pzhj 3306 12 while while IN cord-005646-xhx9pzhj 3306 13 t,2decreased t,2decrease VBN cord-005646-xhx9pzhj 3306 14 markedly markedly RB cord-005646-xhx9pzhj 3306 15 in in IN cord-005646-xhx9pzhj 3306 16 the the DT cord-005646-xhx9pzhj 3306 17 first first JJ cord-005646-xhx9pzhj 3306 18 monthe monthe DT cord-005646-xhx9pzhj 3306 19 of of IN cord-005646-xhx9pzhj 3306 20 life life NN cord-005646-xhx9pzhj 3306 21 ( ( -LRB- cord-005646-xhx9pzhj 3306 22 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 3306 23 ) ) -RRB- cord-005646-xhx9pzhj 3306 24 . . . cord-005646-xhx9pzhj 3307 1 BER BER NNP cord-005646-xhx9pzhj 3307 2 normalized normalize VBD cord-005646-xhx9pzhj 3307 3 for for IN cord-005646-xhx9pzhj 3307 4 dose dose NN cord-005646-xhx9pzhj 3307 5 increased increase VBN cord-005646-xhx9pzhj 3307 6 with with IN cord-005646-xhx9pzhj 3307 7 increasing increase VBG cord-005646-xhx9pzhj 3307 8 age age NN cord-005646-xhx9pzhj 3307 9 . . . cord-005646-xhx9pzhj 3308 1 Patients patient NNS cord-005646-xhx9pzhj 3308 2 with with IN cord-005646-xhx9pzhj 3308 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3308 4 disease disease NN cord-005646-xhx9pzhj 3308 5 exhibited exhibit VBD cord-005646-xhx9pzhj 3308 6 significantly significantly RB cord-005646-xhx9pzhj 3308 7 greater great JJR cord-005646-xhx9pzhj 3308 8 clearance clearance NN cord-005646-xhx9pzhj 3308 9 and and CC cord-005646-xhx9pzhj 3308 10 shorter short JJR cord-005646-xhx9pzhj 3308 11 t~= t~= NNP cord-005646-xhx9pzhj 3308 12 ( ( -LRB- cord-005646-xhx9pzhj 3308 13 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 3308 14 ) ) -RRB- cord-005646-xhx9pzhj 3308 15 than than IN cord-005646-xhx9pzhj 3308 16 those those DT cord-005646-xhx9pzhj 3308 17 with with IN cord-005646-xhx9pzhj 3308 18 cardiac cardiac JJ cord-005646-xhx9pzhj 3308 19 disease disease NN cord-005646-xhx9pzhj 3308 20 whereas whereas IN cord-005646-xhx9pzhj 3308 21 Vd~ Vd~ NNP cord-005646-xhx9pzhj 3308 22 was be VBD cord-005646-xhx9pzhj 3308 23 similar similar JJ cord-005646-xhx9pzhj 3308 24 in in IN cord-005646-xhx9pzhj 3308 25 both both DT cord-005646-xhx9pzhj 3308 26 groups group NNS cord-005646-xhx9pzhj 3308 27 . . . cord-005646-xhx9pzhj 3309 1 The the DT cord-005646-xhx9pzhj 3309 2 administered administer VBN cord-005646-xhx9pzhj 3309 3 dose dose NN cord-005646-xhx9pzhj 3309 4 of of IN cord-005646-xhx9pzhj 3309 5 B B NNP cord-005646-xhx9pzhj 3309 6 was be VBD cord-005646-xhx9pzhj 3309 7 the the DT cord-005646-xhx9pzhj 3309 8 primary primary JJ cord-005646-xhx9pzhj 3309 9 determinant determinant NN cord-005646-xhx9pzhj 3309 10 of of IN cord-005646-xhx9pzhj 3309 11 BER ber NN cord-005646-xhx9pzhj 3309 12 but but CC cord-005646-xhx9pzhj 3309 13 increasing increase VBG cord-005646-xhx9pzhj 3309 14 age age NN cord-005646-xhx9pzhj 3309 15 also also RB cord-005646-xhx9pzhj 3309 16 contributed contribute VBD cord-005646-xhx9pzhj 3309 17 . . . cord-005646-xhx9pzhj 3310 1 Penicillin penicillin JJ cord-005646-xhx9pzhj 3310 2 antibiotics antibiotic NNS cord-005646-xhx9pzhj 3310 3 decreased decrease VBD cord-005646-xhx9pzhj 3310 4 BER BER NNP cord-005646-xhx9pzhj 3310 5 . . . cord-005646-xhx9pzhj 3311 1 Dose dose JJ cord-005646-xhx9pzhj 3311 2 response response NN cord-005646-xhx9pzhj 3311 3 curves curve NNS cord-005646-xhx9pzhj 3311 4 for for IN cord-005646-xhx9pzhj 3311 5 UFR UFR NNP cord-005646-xhx9pzhj 3311 6 and and CC cord-005646-xhx9pzhj 3311 7 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3311 8 excretion excretion NN cord-005646-xhx9pzhj 3311 9 were be VBD cord-005646-xhx9pzhj 3311 10 similar similar JJ cord-005646-xhx9pzhj 3311 11 between between IN cord-005646-xhx9pzhj 3311 12 disease disease NN cord-005646-xhx9pzhj 3311 13 groups group NNS cord-005646-xhx9pzhj 3311 14 . . . cord-005646-xhx9pzhj 3312 1 More More JJR cord-005646-xhx9pzhj 3312 2 of of IN cord-005646-xhx9pzhj 3312 3 the the DT cord-005646-xhx9pzhj 3312 4 variability variability NN cord-005646-xhx9pzhj 3312 5 in in IN cord-005646-xhx9pzhj 3312 6 BER BER NNP cord-005646-xhx9pzhj 3312 7 and and CC cord-005646-xhx9pzhj 3312 8 PD PD NNP cord-005646-xhx9pzhj 3312 9 responses response NNS cord-005646-xhx9pzhj 3312 10 could could MD cord-005646-xhx9pzhj 3312 11 be be VB cord-005646-xhx9pzhj 3312 12 accounted account VBN cord-005646-xhx9pzhj 3312 13 for for IN cord-005646-xhx9pzhj 3312 14 in in IN cord-005646-xhx9pzhj 3312 15 the the DT cord-005646-xhx9pzhj 3312 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3312 17 group group NN cord-005646-xhx9pzhj 3312 18 than than IN cord-005646-xhx9pzhj 3312 19 the the DT cord-005646-xhx9pzhj 3312 20 cardiac cardiac JJ cord-005646-xhx9pzhj 3312 21 group group NN cord-005646-xhx9pzhj 3312 22 but but CC cord-005646-xhx9pzhj 3312 23 this this DT cord-005646-xhx9pzhj 3312 24 was be VBD cord-005646-xhx9pzhj 3312 25 not not RB cord-005646-xhx9pzhj 3312 26 statistically statistically RB cord-005646-xhx9pzhj 3312 27 significant significant JJ cord-005646-xhx9pzhj 3312 28 . . . cord-005646-xhx9pzhj 3313 1 Conclusion conclusion NN cord-005646-xhx9pzhj 3313 2 : : : cord-005646-xhx9pzhj 3314 1 The the DT cord-005646-xhx9pzhj 3314 2 PK PK NNP cord-005646-xhx9pzhj 3314 3 of of IN cord-005646-xhx9pzhj 3314 4 bumetanide bumetanide NN cord-005646-xhx9pzhj 3314 5 were be VBD cord-005646-xhx9pzhj 3314 6 influenced influence VBN cord-005646-xhx9pzhj 3314 7 significantly significantly RB cord-005646-xhx9pzhj 3314 8 by by IN cord-005646-xhx9pzhj 3314 9 age age NN cord-005646-xhx9pzhj 3314 10 and and CC cord-005646-xhx9pzhj 3314 11 disease disease NN cord-005646-xhx9pzhj 3314 12 . . . cord-005646-xhx9pzhj 3315 1 Differences difference NNS cord-005646-xhx9pzhj 3315 2 in in IN cord-005646-xhx9pzhj 3315 3 PK PK NNP cord-005646-xhx9pzhj 3315 4 between between IN cord-005646-xhx9pzhj 3315 5 patients patient NNS cord-005646-xhx9pzhj 3315 6 with with IN cord-005646-xhx9pzhj 3315 7 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3315 8 and and CC cord-005646-xhx9pzhj 3315 9 cardiac cardiac JJ cord-005646-xhx9pzhj 3315 10 disease disease NN cord-005646-xhx9pzhj 3315 11 were be VBD cord-005646-xhx9pzhj 3315 12 primarily primarily RB cord-005646-xhx9pzhj 3315 13 due due JJ cord-005646-xhx9pzhj 3315 14 to to IN cord-005646-xhx9pzhj 3315 15 differences difference NNS cord-005646-xhx9pzhj 3315 16 in in IN cord-005646-xhx9pzhj 3315 17 total total JJ cord-005646-xhx9pzhj 3315 18 clearance clearance NN cord-005646-xhx9pzhj 3315 19 . . . cord-005646-xhx9pzhj 3316 1 Age age NN cord-005646-xhx9pzhj 3316 2 and and CC cord-005646-xhx9pzhj 3316 3 the the DT cord-005646-xhx9pzhj 3316 4 administered administer VBN cord-005646-xhx9pzhj 3316 5 dose dose NN cord-005646-xhx9pzhj 3316 6 of of IN cord-005646-xhx9pzhj 3316 7 B B NNP cord-005646-xhx9pzhj 3316 8 were be VBD cord-005646-xhx9pzhj 3316 9 positive positive JJ cord-005646-xhx9pzhj 3316 10 determinants determinant NNS cord-005646-xhx9pzhj 3316 11 of of IN cord-005646-xhx9pzhj 3316 12 BER BER NNP cord-005646-xhx9pzhj 3316 13 and and CC cord-005646-xhx9pzhj 3316 14 PD PD NNP cord-005646-xhx9pzhj 3316 15 responses response NNS cord-005646-xhx9pzhj 3316 16 while while IN cord-005646-xhx9pzhj 3316 17 penicillin penicillin NN cord-005646-xhx9pzhj 3316 18 antibiotics antibiotic NNS cord-005646-xhx9pzhj 3316 19 had have VBD cord-005646-xhx9pzhj 3316 20 a a DT cord-005646-xhx9pzhj 3316 21 negative negative JJ cord-005646-xhx9pzhj 3316 22 impact impact NN cord-005646-xhx9pzhj 3316 23 on on IN cord-005646-xhx9pzhj 3316 24 both both DT cord-005646-xhx9pzhj 3316 25 , , , cord-005646-xhx9pzhj 3316 26 Once once RB cord-005646-xhx9pzhj 3316 27 B B NNP cord-005646-xhx9pzhj 3316 28 reached reach VBD cord-005646-xhx9pzhj 3316 29 its -PRON- PRP$ cord-005646-xhx9pzhj 3316 30 site site NN cord-005646-xhx9pzhj 3316 31 of of IN cord-005646-xhx9pzhj 3316 32 action action NN cord-005646-xhx9pzhj 3316 33 , , , cord-005646-xhx9pzhj 3316 34 no no DT cord-005646-xhx9pzhj 3316 35 differences difference NNS cord-005646-xhx9pzhj 3316 36 in in IN cord-005646-xhx9pzhj 3316 37 PD PD NNP cord-005646-xhx9pzhj 3316 38 responses response NNS cord-005646-xhx9pzhj 3316 39 were be VBD cord-005646-xhx9pzhj 3316 40 detected detect VBN cord-005646-xhx9pzhj 3316 41 between between IN cord-005646-xhx9pzhj 3316 42 disease disease NN cord-005646-xhx9pzhj 3316 43 groups group NNS cord-005646-xhx9pzhj 3316 44 . . . cord-005646-xhx9pzhj 3317 1 The the DT cord-005646-xhx9pzhj 3317 2 pharmacodynamic pharmacodynamic JJ cord-005646-xhx9pzhj 3317 3 effects effect NNS cord-005646-xhx9pzhj 3317 4 of of IN cord-005646-xhx9pzhj 3317 5 bumetanide bumetanide NN cord-005646-xhx9pzhj 3317 6 were be VBD cord-005646-xhx9pzhj 3317 7 evaluated evaluate VBN cord-005646-xhx9pzhj 3317 8 in in IN cord-005646-xhx9pzhj 3317 9 volume volume NN cord-005646-xhx9pzhj 3317 10 overloaded overload VBN cord-005646-xhx9pzhj 3317 11 infants infant NNS cord-005646-xhx9pzhj 3317 12 ( ( -LRB- cord-005646-xhx9pzhj 3317 13 n=56 n=56 NN cord-005646-xhx9pzhj 3317 14 ) ) -RRB- cord-005646-xhx9pzhj 3317 15 aged age VBN cord-005646-xhx9pzhj 3317 16 4 4 CD cord-005646-xhx9pzhj 3317 17 days-6 days-6 NNP cord-005646-xhx9pzhj 3317 18 months month NNS cord-005646-xhx9pzhj 3317 19 . . . cord-005646-xhx9pzhj 3318 1 Single single JJ cord-005646-xhx9pzhj 3318 2 doses dose NNS cord-005646-xhx9pzhj 3318 3 of of IN cord-005646-xhx9pzhj 3318 4 0.005 0.005 CD cord-005646-xhx9pzhj 3318 5 , , , cord-005646-xhx9pzhj 3318 6 0.01,0.015 0.01,0.015 CD cord-005646-xhx9pzhj 3318 7 , , , cord-005646-xhx9pzhj 3318 8 0.02 0.02 CD cord-005646-xhx9pzhj 3318 9 , , , cord-005646-xhx9pzhj 3318 10 0,025 0,025 CD cord-005646-xhx9pzhj 3318 11 , , , cord-005646-xhx9pzhj 3318 12 0.03 0.03 CD cord-005646-xhx9pzhj 3318 13 , , , cord-005646-xhx9pzhj 3318 14 0.035 0.035 CD cord-005646-xhx9pzhj 3318 15 , , , cord-005646-xhx9pzhj 3318 16 0.05 0.05 CD cord-005646-xhx9pzhj 3318 17 & & CC cord-005646-xhx9pzhj 3318 18 0.10 0.10 CD cord-005646-xhx9pzhj 3318 19 mg mg NNP cord-005646-xhx9pzhj 3319 1 /kg /kg NFP cord-005646-xhx9pzhj 3319 2 IV IV NNP cord-005646-xhx9pzhj 3319 3 were be VBD cord-005646-xhx9pzhj 3319 4 given give VBN cord-005646-xhx9pzhj 3319 5 over over IN cord-005646-xhx9pzhj 3319 6 1 1 CD cord-005646-xhx9pzhj 3319 7 - - SYM cord-005646-xhx9pzhj 3319 8 2 2 CD cord-005646-xhx9pzhj 3319 9 rain rain NN cord-005646-xhx9pzhj 3319 10 . . . cord-005646-xhx9pzhj 3320 1 Bumetanide bumetanide JJ cord-005646-xhx9pzhj 3320 2 concentration concentration NN cord-005646-xhx9pzhj 3320 3 in in IN cord-005646-xhx9pzhj 3320 4 blood blood NN cord-005646-xhx9pzhj 3320 5 ( ( -LRB- cord-005646-xhx9pzhj 3320 6 n n NN cord-005646-xhx9pzhj 3320 7 = = NN cord-005646-xhx9pzhj 3320 8 l l NN cord-005646-xhx9pzhj 3320 9 0 0 CD cord-005646-xhx9pzhj 3320 10 ) ) -RRB- cord-005646-xhx9pzhj 3320 11 & & CC cord-005646-xhx9pzhj 3320 12 urine urine NN cord-005646-xhx9pzhj 3320 13 ( ( -LRB- cord-005646-xhx9pzhj 3321 1 n=6 n=6 NNP cord-005646-xhx9pzhj 3321 2 ) ) -RRB- cord-005646-xhx9pzhj 3321 3 samples sample NNS cord-005646-xhx9pzhj 3321 4 were be VBD cord-005646-xhx9pzhj 3321 5 quantified quantify VBN cord-005646-xhx9pzhj 3321 6 by by IN cord-005646-xhx9pzhj 3321 7 HPLC HPLC NNP cord-005646-xhx9pzhj 3321 8 . . . cord-005646-xhx9pzhj 3322 1 Baseline baseline JJ cord-005646-xhx9pzhj 3322 2 urine urine NN cord-005646-xhx9pzhj 3322 3 samples sample NNS cord-005646-xhx9pzhj 3322 4 were be VBD cord-005646-xhx9pzhj 3322 5 collected collect VBN cord-005646-xhx9pzhj 3322 6 over over IN cord-005646-xhx9pzhj 3322 7 2 2 CD cord-005646-xhx9pzhj 3322 8 - - SYM cord-005646-xhx9pzhj 3322 9 4 4 CD cord-005646-xhx9pzhj 3322 10 hours hour NNS cord-005646-xhx9pzhj 3322 11 prior prior RB cord-005646-xhx9pzhj 3322 12 to to IN cord-005646-xhx9pzhj 3322 13 drug drug NN cord-005646-xhx9pzhj 3322 14 administration administration NN cord-005646-xhx9pzhj 3322 15 . . . cord-005646-xhx9pzhj 3323 1 Determinations determination NNS cord-005646-xhx9pzhj 3323 2 of of IN cord-005646-xhx9pzhj 3323 3 urine urine NN cord-005646-xhx9pzhj 3323 4 volume volume NN cord-005646-xhx9pzhj 3323 5 , , , cord-005646-xhx9pzhj 3323 6 electrolytes electrolyte NNS cord-005646-xhx9pzhj 3323 7 ( ( -LRB- cord-005646-xhx9pzhj 3323 8 Na Na NNP cord-005646-xhx9pzhj 3323 9 " " '' cord-005646-xhx9pzhj 3323 10 , , , cord-005646-xhx9pzhj 3323 11 K K NNP cord-005646-xhx9pzhj 3323 12 + + XX cord-005646-xhx9pzhj 3323 13 , , , cord-005646-xhx9pzhj 3323 14 CI CI NNP cord-005646-xhx9pzhj 3323 15 , , , cord-005646-xhx9pzhj 3324 1 Ca ca NN cord-005646-xhx9pzhj 3324 2 + + CC cord-005646-xhx9pzhj 3324 3 + + CC cord-005646-xhx9pzhj 3324 4 and and CC cord-005646-xhx9pzhj 3324 5 Mg++ Mg++ NNP cord-005646-xhx9pzhj 3324 6 ) ) -RRB- cord-005646-xhx9pzhj 3324 7 , , , cord-005646-xhx9pzhj 3324 8 creatinine creatinine NN cord-005646-xhx9pzhj 3324 9 and and CC cord-005646-xhx9pzhj 3324 10 osmolality osmolality NN cord-005646-xhx9pzhj 3324 11 were be VBD cord-005646-xhx9pzhj 3324 12 performed perform VBN cord-005646-xhx9pzhj 3324 13 before before IN cord-005646-xhx9pzhj 3324 14 and and CC cord-005646-xhx9pzhj 3324 15 at at IN cord-005646-xhx9pzhj 3324 16 0 0 CD cord-005646-xhx9pzhj 3324 17 - - SYM cord-005646-xhx9pzhj 3324 18 1 1 CD cord-005646-xhx9pzhj 3324 19 , , , cord-005646-xhx9pzhj 3324 20 1 1 CD cord-005646-xhx9pzhj 3324 21 - - SYM cord-005646-xhx9pzhj 3324 22 2 2 CD cord-005646-xhx9pzhj 3324 23 , , , cord-005646-xhx9pzhj 3324 24 2 2 CD cord-005646-xhx9pzhj 3324 25 - - SYM cord-005646-xhx9pzhj 3324 26 3 3 CD cord-005646-xhx9pzhj 3324 27 , , , cord-005646-xhx9pzhj 3324 28 3 3 CD cord-005646-xhx9pzhj 3324 29 - - SYM cord-005646-xhx9pzhj 3324 30 4 4 CD cord-005646-xhx9pzhj 3324 31 , , , cord-005646-xhx9pzhj 3324 32 4 4 CD cord-005646-xhx9pzhj 3324 33 - - SYM cord-005646-xhx9pzhj 3324 34 6 6 CD cord-005646-xhx9pzhj 3324 35 and and CC cord-005646-xhx9pzhj 3324 36 6 6 CD cord-005646-xhx9pzhj 3324 37 - - SYM cord-005646-xhx9pzhj 3324 38 12 12 CD cord-005646-xhx9pzhj 3324 39 hours hour NNS cord-005646-xhx9pzhj 3324 40 after after IN cord-005646-xhx9pzhj 3324 41 bumetanide bumetanide NN cord-005646-xhx9pzhj 3324 42 dosing dosing NN cord-005646-xhx9pzhj 3324 43 . . . cord-005646-xhx9pzhj 3325 1 Changes change NNS cord-005646-xhx9pzhj 3325 2 in in IN cord-005646-xhx9pzhj 3325 3 urine urine NN cord-005646-xhx9pzhj 3325 4 flow flow NN cord-005646-xhx9pzhj 3325 5 rate rate NN cord-005646-xhx9pzhj 3325 6 and and CC cord-005646-xhx9pzhj 3325 7 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3325 8 excretion excretion NN cord-005646-xhx9pzhj 3325 9 were be VBD cord-005646-xhx9pzhj 3325 10 plotted plot VBN cord-005646-xhx9pzhj 3325 11 as as IN cord-005646-xhx9pzhj 3325 12 a a DT cord-005646-xhx9pzhj 3325 13 function function NN cord-005646-xhx9pzhj 3325 14 of of IN cord-005646-xhx9pzhj 3325 15 bumetanide bumetanide NN cord-005646-xhx9pzhj 3325 16 excretion excretion NN cord-005646-xhx9pzhj 3325 17 rate rate NN cord-005646-xhx9pzhj 3325 18 which which WDT cord-005646-xhx9pzhj 3325 19 was be VBD cord-005646-xhx9pzhj 3325 20 considered consider VBN cord-005646-xhx9pzhj 3325 21 the the DT cord-005646-xhx9pzhj 3325 22 effective effective JJ cord-005646-xhx9pzhj 3325 23 dose dose NN cord-005646-xhx9pzhj 3325 24 of of IN cord-005646-xhx9pzhj 3325 25 the the DT cord-005646-xhx9pzhj 3325 26 drug drug NN cord-005646-xhx9pzhj 3325 27 . . . cord-005646-xhx9pzhj 3326 1 Peak peak JJ cord-005646-xhx9pzhj 3326 2 bumetanide bumetanide NN cord-005646-xhx9pzhj 3326 3 excretion excretion NN cord-005646-xhx9pzhj 3326 4 rate rate NN cord-005646-xhx9pzhj 3326 5 increased increase VBD cord-005646-xhx9pzhj 3326 6 linearly linearly RB cord-005646-xhx9pzhj 3326 7 with with IN cord-005646-xhx9pzhj 3326 8 increasing increase VBG cord-005646-xhx9pzhj 3326 9 doses dose NNS cord-005646-xhx9pzhj 3326 10 of of IN cord-005646-xhx9pzhj 3326 11 drug drug NN cord-005646-xhx9pzhj 3326 12 and and CC cord-005646-xhx9pzhj 3326 13 showed show VBD cord-005646-xhx9pzhj 3326 14 no no DT cord-005646-xhx9pzhj 3326 15 evidence evidence NN cord-005646-xhx9pzhj 3326 16 of of IN cord-005646-xhx9pzhj 3326 17 approaching approach VBG cord-005646-xhx9pzhj 3326 18 a a DT cord-005646-xhx9pzhj 3326 19 maximum maximum NN cord-005646-xhx9pzhj 3326 20 . . . cord-005646-xhx9pzhj 3327 1 Time time NN cord-005646-xhx9pzhj 3327 2 course course NN cord-005646-xhx9pzhj 3327 3 patterns pattern NNS cord-005646-xhx9pzhj 3327 4 for for IN cord-005646-xhx9pzhj 3327 5 urine urine NN cord-005646-xhx9pzhj 3327 6 flow flow NN cord-005646-xhx9pzhj 3327 7 rate rate NN cord-005646-xhx9pzhj 3327 8 and and CC cord-005646-xhx9pzhj 3327 9 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3327 10 excretion excretion NN cord-005646-xhx9pzhj 3327 11 were be VBD cord-005646-xhx9pzhj 3327 12 similar similar JJ cord-005646-xhx9pzhj 3327 13 for for IN cord-005646-xhx9pzhj 3327 14 all all DT cord-005646-xhx9pzhj 3327 15 dosage dosage NN cord-005646-xhx9pzhj 3327 16 groups group NNS cord-005646-xhx9pzhj 3327 17 . . . cord-005646-xhx9pzhj 3328 1 Urine urine NN cord-005646-xhx9pzhj 3328 2 flow flow NN cord-005646-xhx9pzhj 3328 3 rate rate NN cord-005646-xhx9pzhj 3328 4 and and CC cord-005646-xhx9pzhj 3328 5 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3328 6 excretion excretion NN cord-005646-xhx9pzhj 3328 7 increased increase VBD cord-005646-xhx9pzhj 3328 8 lineady lineady NNP cord-005646-xhx9pzhj 3328 9 up up IN cord-005646-xhx9pzhj 3328 10 to to IN cord-005646-xhx9pzhj 3328 11 a a DT cord-005646-xhx9pzhj 3328 12 bumetanide bumetanide NN cord-005646-xhx9pzhj 3328 13 excretion excretion NN cord-005646-xhx9pzhj 3328 14 rate rate NN cord-005646-xhx9pzhj 3328 15 of of IN cord-005646-xhx9pzhj 3328 16 approximately approximately RB cord-005646-xhx9pzhj 3328 17 7 7 CD cord-005646-xhx9pzhj 3328 18 # # NN cord-005646-xhx9pzhj 3328 19 g g NN cord-005646-xhx9pzhj 3328 20 / / SYM cord-005646-xhx9pzhj 3328 21 kg kg NNP cord-005646-xhx9pzhj 3328 22 / / SYM cord-005646-xhx9pzhj 3328 23 hr hr NN cord-005646-xhx9pzhj 3328 24 and and CC cord-005646-xhx9pzhj 3328 25 either either RB cord-005646-xhx9pzhj 3328 26 plateaued plateaue VBN cord-005646-xhx9pzhj 3328 27 ( ( -LRB- cord-005646-xhx9pzhj 3328 28 urine urine NN cord-005646-xhx9pzhj 3328 29 flow flow NN cord-005646-xhx9pzhj 3328 30 rate rate NN cord-005646-xhx9pzhj 3328 31 ) ) -RRB- cord-005646-xhx9pzhj 3328 32 or or CC cord-005646-xhx9pzhj 3328 33 declined decline VBD cord-005646-xhx9pzhj 3328 34 at at IN cord-005646-xhx9pzhj 3328 35 bumetanide bumetanide NN cord-005646-xhx9pzhj 3328 36 excretion excretion NN cord-005646-xhx9pzhj 3328 37 rates rate NNS cord-005646-xhx9pzhj 3328 38 > > XX cord-005646-xhx9pzhj 3329 1 10 10 CD cord-005646-xhx9pzhj 3329 2 # # $ cord-005646-xhx9pzhj 3329 3 g g NN cord-005646-xhx9pzhj 3329 4 / / SYM cord-005646-xhx9pzhj 3329 5 kg kg NNP cord-005646-xhx9pzhj 3329 6 / / SYM cord-005646-xhx9pzhj 3329 7 hr hr NN cord-005646-xhx9pzhj 3329 8 . . . cord-005646-xhx9pzhj 3330 1 Bumetanide Bumetanide NNP cord-005646-xhx9pzhj 3330 2 had have VBD cord-005646-xhx9pzhj 3330 3 no no DT cord-005646-xhx9pzhj 3330 4 detectable detectable JJ cord-005646-xhx9pzhj 3330 5 effect effect NN cord-005646-xhx9pzhj 3330 6 on on IN cord-005646-xhx9pzhj 3330 7 serum serum NN cord-005646-xhx9pzhj 3330 8 electrolyte electrolyte JJ cord-005646-xhx9pzhj 3330 9 concentrations concentration NNS cord-005646-xhx9pzhj 3330 10 , , , cord-005646-xhx9pzhj 3330 11 Conclusion conclusion NN cord-005646-xhx9pzhj 3330 12 : : : cord-005646-xhx9pzhj 3330 13 Maximal maximal JJ cord-005646-xhx9pzhj 3330 14 diuretic diuretic JJ cord-005646-xhx9pzhj 3330 15 responses response NNS cord-005646-xhx9pzhj 3330 16 occurred occur VBD cord-005646-xhx9pzhj 3330 17 at at IN cord-005646-xhx9pzhj 3330 18 a a DT cord-005646-xhx9pzhj 3330 19 bumetanide bumetanide NN cord-005646-xhx9pzhj 3330 20 excretion excretion NN cord-005646-xhx9pzhj 3330 21 rate rate NN cord-005646-xhx9pzhj 3330 22 of of IN cord-005646-xhx9pzhj 3330 23 about about RB cord-005646-xhx9pzhj 3330 24 7 7 CD cord-005646-xhx9pzhj 3330 25 ; ; . cord-005646-xhx9pzhj 3331 1 ~g ~g NNP cord-005646-xhx9pzhj 3331 2 / / SYM cord-005646-xhx9pzhj 3331 3 kg kg NNP cord-005646-xhx9pzhj 3331 4 / / SYM cord-005646-xhx9pzhj 3331 5 hr hr NN cord-005646-xhx9pzhj 3331 6 . . . cord-005646-xhx9pzhj 3332 1 Higher high JJR cord-005646-xhx9pzhj 3332 2 bumetanide bumetanide NN cord-005646-xhx9pzhj 3332 3 excretion excretion NN cord-005646-xhx9pzhj 3332 4 rates rate NNS cord-005646-xhx9pzhj 3332 5 produced produce VBD cord-005646-xhx9pzhj 3332 6 no no DT cord-005646-xhx9pzhj 3332 7 increased increase VBN cord-005646-xhx9pzhj 3332 8 diuretic diuretic JJ cord-005646-xhx9pzhj 3332 9 effect effect NN cord-005646-xhx9pzhj 3332 10 . . . cord-005646-xhx9pzhj 3333 1 Peak peak JJ cord-005646-xhx9pzhj 3333 2 bumetanide bumetanide NN cord-005646-xhx9pzhj 3333 3 excretion excretion NN cord-005646-xhx9pzhj 3333 4 rate rate NN cord-005646-xhx9pzhj 3333 5 of of IN cord-005646-xhx9pzhj 3333 6 about about RB cord-005646-xhx9pzhj 3333 7 7 7 CD cord-005646-xhx9pzhj 3333 8 # # NN cord-005646-xhx9pzhj 3333 9 g g NN cord-005646-xhx9pzhj 3333 10 / / SYM cord-005646-xhx9pzhj 3333 11 kg kg NNP cord-005646-xhx9pzhj 3333 12 / / SYM cord-005646-xhx9pzhj 3333 13 hr hr NNP cord-005646-xhx9pzhj 3333 14 corresponded correspond VBD cord-005646-xhx9pzhj 3333 15 to to IN cord-005646-xhx9pzhj 3333 16 bumetanide bumetanide JJ cord-005646-xhx9pzhj 3333 17 doses dose NNS cord-005646-xhx9pzhj 3333 18 of of IN cord-005646-xhx9pzhj 3333 19 0.035 0.035 CD cord-005646-xhx9pzhj 3333 20 - - SYM cord-005646-xhx9pzhj 3333 21 0.050 0.050 CD cord-005646-xhx9pzhj 3333 22 mg mg NNP cord-005646-xhx9pzhj 3333 23 / / SYM cord-005646-xhx9pzhj 3333 24 kg kg NN cord-005646-xhx9pzhj 3333 25 . . . cord-005646-xhx9pzhj 3334 1 Neonates neonate NNS cord-005646-xhx9pzhj 3334 2 Using use VBG cord-005646-xhx9pzhj 3334 3 An an DT cord-005646-xhx9pzhj 3334 4 Electrical Electrical NNP cord-005646-xhx9pzhj 3334 5 Syringe Syringe NNP cord-005646-xhx9pzhj 3334 6 - - HYPH cord-005646-xhx9pzhj 3334 7 Pump Pump NNP cord-005646-xhx9pzhj 3334 8 . . . cord-005646-xhx9pzhj 3335 1 authors author NNS cord-005646-xhx9pzhj 3335 2 : : : cord-005646-xhx9pzhj 3335 3 Tr Tr NNP cord-005646-xhx9pzhj 3335 4 ~ ~ CD cord-005646-xhx9pzhj 3335 5 luyer luyer NNP cord-005646-xhx9pzhj 3335 6 J.M. J.M. NNP cord-005646-xhx9pzhj 3335 7 , , , cord-005646-xhx9pzhj 3335 8 Sertin Sertin NNP cord-005646-xhx9pzhj 3335 9 A. A. NNP cord-005646-xhx9pzhj 3335 10 , , , cord-005646-xhx9pzhj 3335 11 Bastard Bastard NNP cord-005646-xhx9pzhj 3335 12 V. V. NNP cord-005646-xhx9pzhj 3335 13 , , , cord-005646-xhx9pzhj 3335 14 Settegrana Settegrana NNP cord-005646-xhx9pzhj 3335 15 , , , cord-005646-xhx9pzhj 3335 16 C. C. NNP cord-005646-xhx9pzhj 3335 17 , , , cord-005646-xhx9pzhj 3335 18 Bourget Bourget NNP cord-005646-xhx9pzhj 3335 19 P. P. NNP cord-005646-xhx9pzhj 3335 20 , , , cord-005646-xhx9pzhj 3335 21 Hubert Hubert NNP cord-005646-xhx9pzhj 3335 22 P. P. NNP cord-005646-xhx9pzhj 3335 23 Background Background NNP cord-005646-xhx9pzhj 3335 24 and and CC cord-005646-xhx9pzhj 3335 25 objective objective NN cord-005646-xhx9pzhj 3335 26 : : : cord-005646-xhx9pzhj 3336 1 many many JJ cord-005646-xhx9pzhj 3336 2 problems problem NNS cord-005646-xhx9pzhj 3336 3 can can MD cord-005646-xhx9pzhj 3336 4 be be VB cord-005646-xhx9pzhj 3336 5 observed observe VBN cord-005646-xhx9pzhj 3336 6 with with IN cord-005646-xhx9pzhj 3336 7 drug drug NN cord-005646-xhx9pzhj 3336 8 administration administration NN cord-005646-xhx9pzhj 3336 9 by by IN cord-005646-xhx9pzhj 3336 10 i.v i.v NNP cord-005646-xhx9pzhj 3336 11 . . NNP cord-005646-xhx9pzhj 3336 12 route route NNP cord-005646-xhx9pzhj 3336 13 , , , cord-005646-xhx9pzhj 3336 14 especially especially RB cord-005646-xhx9pzhj 3336 15 in in IN cord-005646-xhx9pzhj 3336 16 neonates neonate NNS cord-005646-xhx9pzhj 3336 17 . . . cord-005646-xhx9pzhj 3337 1 So so RB cord-005646-xhx9pzhj 3337 2 we -PRON- PRP cord-005646-xhx9pzhj 3337 3 evaluate evaluate VBP cord-005646-xhx9pzhj 3337 4 different different JJ cord-005646-xhx9pzhj 3337 5 protocols protocol NNS cord-005646-xhx9pzhj 3337 6 of of IN cord-005646-xhx9pzhj 3337 7 Teico Teico NNP cord-005646-xhx9pzhj 3337 8 delivery delivery NN cord-005646-xhx9pzhj 3337 9 using use VBG cord-005646-xhx9pzhj 3337 10 an an DT cord-005646-xhx9pzhj 3337 11 electrical electrical JJ cord-005646-xhx9pzhj 3337 12 syringe syringe NN cord-005646-xhx9pzhj 3337 13 - - HYPH cord-005646-xhx9pzhj 3337 14 pump pump NN cord-005646-xhx9pzhj 3337 15 . . . cord-005646-xhx9pzhj 3338 1 Methods method NNS cord-005646-xhx9pzhj 3338 2 : : : cord-005646-xhx9pzhj 3338 3 we -PRON- PRP cord-005646-xhx9pzhj 3338 4 simulate simulate VBP cord-005646-xhx9pzhj 3338 5 infusion infusion NN cord-005646-xhx9pzhj 3338 6 of of IN cord-005646-xhx9pzhj 3338 7 Teico Teico NNP cord-005646-xhx9pzhj 3338 8 with with IN cord-005646-xhx9pzhj 3338 9 a a DT cord-005646-xhx9pzhj 3338 10 syrlnge syrlnge NN cord-005646-xhx9pzhj 3338 11 - - NN cord-005646-xhx9pzhj 3338 12 pump pump NN cord-005646-xhx9pzhj 3338 13 ( ( -LRB- cord-005646-xhx9pzhj 3338 14 Pilot Pilot NNP cord-005646-xhx9pzhj 3338 15 C C NNP cord-005646-xhx9pzhj 3338 16 , , , cord-005646-xhx9pzhj 3338 17 Becton Becton NNP cord-005646-xhx9pzhj 3338 18 & & CC cord-005646-xhx9pzhj 3338 19 Dickinson Dickinson NNP cord-005646-xhx9pzhj 3338 20 Lab Lab NNP cord-005646-xhx9pzhj 3338 21 . . . cord-005646-xhx9pzhj 3338 22 ) ) -RRB- cord-005646-xhx9pzhj 3339 1 trough trough NNP cord-005646-xhx9pzhj 3339 2 d d NNP cord-005646-xhx9pzhj 3339 3 standart standart NNP cord-005646-xhx9pzhj 3339 4 neonatal neonatal JJ cord-005646-xhx9pzhj 3339 5 I.V. I.V. NNP cord-005646-xhx9pzhj 3339 6 system system NN cord-005646-xhx9pzhj 3339 7 . . . cord-005646-xhx9pzhj 3340 1 For for IN cord-005646-xhx9pzhj 3340 2 2 2 CD cord-005646-xhx9pzhj 3340 3 weights weight NNS cord-005646-xhx9pzhj 3340 4 ( ( -LRB- cord-005646-xhx9pzhj 3340 5 1 1 CD cord-005646-xhx9pzhj 3340 6 or or CC cord-005646-xhx9pzhj 3340 7 3 3 CD cord-005646-xhx9pzhj 3340 8 kg kg NNS cord-005646-xhx9pzhj 3340 9 ) ) -RRB- cord-005646-xhx9pzhj 3340 10 we -PRON- PRP cord-005646-xhx9pzhj 3340 11 used use VBD cord-005646-xhx9pzhj 3340 12 2 2 CD cord-005646-xhx9pzhj 3340 13 doses dose NNS cord-005646-xhx9pzhj 3340 14 of of IN cord-005646-xhx9pzhj 3340 15 Teico Teico NNP cord-005646-xhx9pzhj 3340 16 ( ( -LRB- cord-005646-xhx9pzhj 3340 17 8 8 CD cord-005646-xhx9pzhj 3340 18 mg mg NN cord-005646-xhx9pzhj 3340 19 and and CC cord-005646-xhx9pzhj 3340 20 16 16 CD cord-005646-xhx9pzhj 3340 21 mg mg NNP cord-005646-xhx9pzhj 3340 22 / / SYM cord-005646-xhx9pzhj 3340 23 kg kg NNP cord-005646-xhx9pzhj 3340 24 ) ) -RRB- cord-005646-xhx9pzhj 3340 25 and and CC cord-005646-xhx9pzhj 3340 26 a a DT cord-005646-xhx9pzhj 3340 27 dose dose JJ cord-005646-xhx9pzhj 3340 28 volume volume NN cord-005646-xhx9pzhj 3340 29 _ _ NN cord-005646-xhx9pzhj 3340 30 < < XX cord-005646-xhx9pzhj 3340 31 4.2 4.2 CD cord-005646-xhx9pzhj 3340 32 ml ml NNS cord-005646-xhx9pzhj 3340 33 . . . cord-005646-xhx9pzhj 3341 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 3341 2 goal goal NN cord-005646-xhx9pzhj 3341 3 was be VBD cord-005646-xhx9pzhj 3341 4 to to TO cord-005646-xhx9pzhj 3341 5 perform perform VB cord-005646-xhx9pzhj 3341 6 a a DT cord-005646-xhx9pzhj 3341 7 complete complete JJ cord-005646-xhx9pzhj 3341 8 infusion infusion NN cord-005646-xhx9pzhj 3341 9 in in IN cord-005646-xhx9pzhj 3341 10 10 10 CD cord-005646-xhx9pzhj 3341 11 minutes minute NNS cord-005646-xhx9pzhj 3341 12 . . . cord-005646-xhx9pzhj 3342 1 The the DT cord-005646-xhx9pzhj 3342 2 infusion infusion NN cord-005646-xhx9pzhj 3342 3 system system NN cord-005646-xhx9pzhj 3342 4 consisted consist VBD cord-005646-xhx9pzhj 3342 5 of of IN cord-005646-xhx9pzhj 3342 6 an an DT cord-005646-xhx9pzhj 3342 7 Life Life NNP cord-005646-xhx9pzhj 3342 8 Care Care NNP cord-005646-xhx9pzhj 3342 9 4 4 CD cord-005646-xhx9pzhj 3342 10 infusion infusion NN cord-005646-xhx9pzhj 3342 11 pump pump NN cord-005646-xhx9pzhj 3342 12 ( ( -LRB- cord-005646-xhx9pzhj 3342 13 ABBOTT ABBOTT NNP cord-005646-xhx9pzhj 3342 14 Lab Lab NNP cord-005646-xhx9pzhj 3342 15 . . . cord-005646-xhx9pzhj 3342 16 ) ) -RRB- cord-005646-xhx9pzhj 3342 17 with with IN cord-005646-xhx9pzhj 3342 18 its -PRON- PRP$ cord-005646-xhx9pzhj 3342 19 LV LV NNP cord-005646-xhx9pzhj 3342 20 . . . cord-005646-xhx9pzhj 3343 1 set set VBN cord-005646-xhx9pzhj 3343 2 for for IN cord-005646-xhx9pzhj 3343 3 maintenance maintenance NN cord-005646-xhx9pzhj 3343 4 intravenous intravenous JJ cord-005646-xhx9pzhj 3343 5 fluid fluid NN cord-005646-xhx9pzhj 3343 6 ( ( -LRB- cord-005646-xhx9pzhj 3343 7 flow flow NN cord-005646-xhx9pzhj 3343 8 _ _ NN cord-005646-xhx9pzhj 3343 9 < < XX cord-005646-xhx9pzhj 3343 10 6 6 CD cord-005646-xhx9pzhj 3343 11 ml ml NN cord-005646-xhx9pzhj 3343 12 / / SYM cord-005646-xhx9pzhj 3343 13 h h NN cord-005646-xhx9pzhj 3343 14 ) ) -RRB- cord-005646-xhx9pzhj 3343 15 connected connect VBN cord-005646-xhx9pzhj 3343 16 to to IN cord-005646-xhx9pzhj 3343 17 a a DT cord-005646-xhx9pzhj 3343 18 3-way 3-way JJ cord-005646-xhx9pzhj 3343 19 stopcock stopcock NN cord-005646-xhx9pzhj 3343 20 . . . cord-005646-xhx9pzhj 3344 1 An an DT cord-005646-xhx9pzhj 3344 2 1 1 CD cord-005646-xhx9pzhj 3344 3 meter meter NN cord-005646-xhx9pzhj 3344 4 extension extension NN cord-005646-xhx9pzhj 3344 5 tubing tubing NN cord-005646-xhx9pzhj 3344 6 was be VBD cord-005646-xhx9pzhj 3344 7 placed place VBN cord-005646-xhx9pzhj 3344 8 between between IN cord-005646-xhx9pzhj 3344 9 the the DT cord-005646-xhx9pzhj 3344 10 stopcock stopcock NN cord-005646-xhx9pzhj 3344 11 and and CC cord-005646-xhx9pzhj 3344 12 a a DT cord-005646-xhx9pzhj 3344 13 neonatal neonatal JJ cord-005646-xhx9pzhj 3344 14 catheter catheter NN cord-005646-xhx9pzhj 3344 15 . . . cord-005646-xhx9pzhj 3345 1 An an DT cord-005646-xhx9pzhj 3345 2 another another DT cord-005646-xhx9pzhj 3345 3 1 1 CD cord-005646-xhx9pzhj 3345 4 meter meter NN cord-005646-xhx9pzhj 3345 5 tubing tubing NN cord-005646-xhx9pzhj 3345 6 ( ( -LRB- cord-005646-xhx9pzhj 3345 7 injection injection NN cord-005646-xhx9pzhj 3345 8 tubing tubing NN cord-005646-xhx9pzhj 3345 9 ) ) -RRB- cord-005646-xhx9pzhj 3345 10 connected connect VBD cord-005646-xhx9pzhj 3345 11 the the DT cord-005646-xhx9pzhj 3345 12 Teicoplanine Teicoplanine NNP cord-005646-xhx9pzhj 3345 13 syringe syringe NN cord-005646-xhx9pzhj 3345 14 to to IN cord-005646-xhx9pzhj 3345 15 the the DT cord-005646-xhx9pzhj 3345 16 stopc stopc NNP cord-005646-xhx9pzhj 3345 17 , , , cord-005646-xhx9pzhj 3345 18 ock ock NNP cord-005646-xhx9pzhj 3345 19 . . . cord-005646-xhx9pzhj 3346 1 The the DT cord-005646-xhx9pzhj 3346 2 volume volume NN cord-005646-xhx9pzhj 3346 3 of of IN cord-005646-xhx9pzhj 3346 4 the the DT cord-005646-xhx9pzhj 3346 5 injection injection NN cord-005646-xhx9pzhj 3346 6 circuit circuit NN cord-005646-xhx9pzhj 3346 7 ( ( -LRB- cord-005646-xhx9pzhj 3346 8 from from IN cord-005646-xhx9pzhj 3346 9 the the DT cord-005646-xhx9pzhj 3346 10 syringe syringe NN cord-005646-xhx9pzhj 3346 11 to to IN cord-005646-xhx9pzhj 3346 12 the the DT cord-005646-xhx9pzhj 3346 13 distal distal JJ cord-005646-xhx9pzhj 3346 14 part part NN cord-005646-xhx9pzhj 3346 15 of of IN cord-005646-xhx9pzhj 3346 16 the the DT cord-005646-xhx9pzhj 3346 17 catheter catheter NN cord-005646-xhx9pzhj 3346 18 was be VBD cord-005646-xhx9pzhj 3346 19 2.6 2.6 CD cord-005646-xhx9pzhj 3346 20 mL ml NN cord-005646-xhx9pzhj 3346 21 4 4 CD cord-005646-xhx9pzhj 3346 22 methods method NNS cord-005646-xhx9pzhj 3346 23 of of IN cord-005646-xhx9pzhj 3346 24 injections injection NNS cord-005646-xhx9pzhj 3346 25 were be VBD cord-005646-xhx9pzhj 3346 26 assessed assess VBN cord-005646-xhx9pzhj 3346 27 : : : cord-005646-xhx9pzhj 3347 1 A a LS cord-005646-xhx9pzhj 3347 2 : : : cord-005646-xhx9pzhj 3347 3 Injection injection NN cord-005646-xhx9pzhj 3347 4 of of IN cord-005646-xhx9pzhj 3347 5 the the DT cord-005646-xhx9pzhj 3347 6 predetermined predetermined JJ cord-005646-xhx9pzhj 3347 7 volume volume NN cord-005646-xhx9pzhj 3347 8 of of IN cord-005646-xhx9pzhj 3347 9 Teico Teico NNP cord-005646-xhx9pzhj 3347 10 in in IN cord-005646-xhx9pzhj 3347 11 10 10 CD cord-005646-xhx9pzhj 3347 12 minutes minute NNS cord-005646-xhx9pzhj 3347 13 with with IN cord-005646-xhx9pzhj 3347 14 no no DT cord-005646-xhx9pzhj 3347 15 wash wash NN cord-005646-xhx9pzhj 3347 16 out out RP cord-005646-xhx9pzhj 3347 17 . . . cord-005646-xhx9pzhj 3348 1 B b NN cord-005646-xhx9pzhj 3348 2 : : : cord-005646-xhx9pzhj 3349 1 Idem Idem NNP cord-005646-xhx9pzhj 3349 2 as as IN cord-005646-xhx9pzhj 3349 3 A a NN cord-005646-xhx9pzhj 3350 1 but but CC cord-005646-xhx9pzhj 3350 2 the the DT cord-005646-xhx9pzhj 3350 3 Teico Teico NNP cord-005646-xhx9pzhj 3350 4 was be VBD cord-005646-xhx9pzhj 3350 5 injected inject VBN cord-005646-xhx9pzhj 3350 6 in in IN cord-005646-xhx9pzhj 3350 7 5 5 CD cord-005646-xhx9pzhj 3350 8 minutes minute NNS cord-005646-xhx9pzhj 3350 9 , , , cord-005646-xhx9pzhj 3350 10 followed follow VBN cord-005646-xhx9pzhj 3350 11 by by IN cord-005646-xhx9pzhj 3350 12 a a DT cord-005646-xhx9pzhj 3350 13 wash wash NN cord-005646-xhx9pzhj 3350 14 out out RP cord-005646-xhx9pzhj 3350 15 ( ( -LRB- cord-005646-xhx9pzhj 3350 16 5 5 CD cord-005646-xhx9pzhj 3350 17 ml ml NN cord-005646-xhx9pzhj 3350 18 / / SYM cord-005646-xhx9pzhj 3350 19 5 5 CD cord-005646-xhx9pzhj 3350 20 minutes minute NNS cord-005646-xhx9pzhj 3350 21 ) ) -RRB- cord-005646-xhx9pzhj 3350 22 . . . cord-005646-xhx9pzhj 3351 1 C C NNP cord-005646-xhx9pzhj 3351 2 : : : cord-005646-xhx9pzhj 3352 1 Twice twice PDT cord-005646-xhx9pzhj 3352 2 the the DT cord-005646-xhx9pzhj 3352 3 required required JJ cord-005646-xhx9pzhj 3352 4 volume volume NN cord-005646-xhx9pzhj 3352 5 was be VBD cord-005646-xhx9pzhj 3352 6 introduced introduce VBN cord-005646-xhx9pzhj 3352 7 in in IN cord-005646-xhx9pzhj 3352 8 the the DT cord-005646-xhx9pzhj 3352 9 syringe syringe NN cord-005646-xhx9pzhj 3352 10 and and CC cord-005646-xhx9pzhj 3352 11 the the DT cord-005646-xhx9pzhj 3352 12 volume volume NN cord-005646-xhx9pzhj 3352 13 to to TO cord-005646-xhx9pzhj 3352 14 infuse infuse VB cord-005646-xhx9pzhj 3352 15 was be VBD cord-005646-xhx9pzhj 3352 16 programed program VBN cord-005646-xhx9pzhj 3352 17 in in IN cord-005646-xhx9pzhj 3352 18 5 5 CD cord-005646-xhx9pzhj 3352 19 minutes minute NNS cord-005646-xhx9pzhj 3352 20 , , , cord-005646-xhx9pzhj 3352 21 followed follow VBN cord-005646-xhx9pzhj 3352 22 by by IN cord-005646-xhx9pzhj 3352 23 a a DT cord-005646-xhx9pzhj 3352 24 wash wash NN cord-005646-xhx9pzhj 3352 25 out out RP cord-005646-xhx9pzhj 3352 26 ( ( -LRB- cord-005646-xhx9pzhj 3352 27 5 5 CD cord-005646-xhx9pzhj 3352 28 ml/5 ml/5 NN cord-005646-xhx9pzhj 3352 29 minutes minute NNS cord-005646-xhx9pzhj 3352 30 ) ) -RRB- cord-005646-xhx9pzhj 3352 31 . . . cord-005646-xhx9pzhj 3353 1 D D NNP cord-005646-xhx9pzhj 3353 2 : : : cord-005646-xhx9pzhj 3353 3 ] ] -RRB- cord-005646-xhx9pzhj 3353 4 dem dem VBP cord-005646-xhx9pzhj 3353 5 as as IN cord-005646-xhx9pzhj 3353 6 C C NNP cord-005646-xhx9pzhj 3353 7 but but CC cord-005646-xhx9pzhj 3353 8 a a DT cord-005646-xhx9pzhj 3353 9 priming priming NN cord-005646-xhx9pzhj 3353 10 was be VBD cord-005646-xhx9pzhj 3353 11 performed perform VBN cord-005646-xhx9pzhj 3353 12 before before IN cord-005646-xhx9pzhj 3353 13 connecting connect VBG cord-005646-xhx9pzhj 3353 14 theTeico theTeico NNP cord-005646-xhx9pzhj 3353 15 syringe syringe NN cord-005646-xhx9pzhj 3353 16 to to IN cord-005646-xhx9pzhj 3353 17 the the DT cord-005646-xhx9pzhj 3353 18 tubing tubing NN cord-005646-xhx9pzhj 3353 19 . . . cord-005646-xhx9pzhj 3354 1 During during IN cord-005646-xhx9pzhj 3354 2 each each DT cord-005646-xhx9pzhj 3354 3 run run NN cord-005646-xhx9pzhj 3354 4 , , , cord-005646-xhx9pzhj 3354 5 serial serial JJ cord-005646-xhx9pzhj 3354 6 samples sample NNS cord-005646-xhx9pzhj 3354 7 were be VBD cord-005646-xhx9pzhj 3354 8 collected collect VBN cord-005646-xhx9pzhj 3354 9 every every DT cord-005646-xhx9pzhj 3354 10 ten ten CD cord-005646-xhx9pzhj 3354 11 minutes minute NNS cord-005646-xhx9pzhj 3354 12 over over IN cord-005646-xhx9pzhj 3354 13 a a DT cord-005646-xhx9pzhj 3354 14 one one CD cord-005646-xhx9pzhj 3354 15 hour hour NN cord-005646-xhx9pzhj 3354 16 period period NN cord-005646-xhx9pzhj 3354 17 . . . cord-005646-xhx9pzhj 3355 1 The the DT cord-005646-xhx9pzhj 3355 2 samples sample NNS cord-005646-xhx9pzhj 3355 3 were be VBD cord-005646-xhx9pzhj 3355 4 assessed assess VBN cord-005646-xhx9pzhj 3355 5 using use VBG cord-005646-xhx9pzhj 3355 6 HPLC HPLC NNP cord-005646-xhx9pzhj 3355 7 method method NN cord-005646-xhx9pzhj 3355 8 . . . cord-005646-xhx9pzhj 3356 1 Results result NNS cord-005646-xhx9pzhj 3356 2 : : : cord-005646-xhx9pzhj 3356 3 the the DT cord-005646-xhx9pzhj 3356 4 amount amount NN cord-005646-xhx9pzhj 3356 5 of of IN cord-005646-xhx9pzhj 3356 6 drug drug NN cord-005646-xhx9pzhj 3356 7 delivred delivre VBN cord-005646-xhx9pzhj 3356 8 at at IN cord-005646-xhx9pzhj 3356 9 10 10 CD cord-005646-xhx9pzhj 3356 10 minutes minute NNS cord-005646-xhx9pzhj 3356 11 were be VBD cord-005646-xhx9pzhj 3356 12 calculated calculate VBN cord-005646-xhx9pzhj 3356 13 . . . cord-005646-xhx9pzhj 3357 1 The the DT cord-005646-xhx9pzhj 3357 2 results result NNS cord-005646-xhx9pzhj 3357 3 are be VBP cord-005646-xhx9pzhj 3357 4 a a DT cord-005646-xhx9pzhj 3357 5 mean mean NN cord-005646-xhx9pzhj 3357 6 of of IN cord-005646-xhx9pzhj 3357 7 2 2 CD cord-005646-xhx9pzhj 3357 8 to to TO cord-005646-xhx9pzhj 3357 9 6 6 CD cord-005646-xhx9pzhj 3357 10 runs run NNS cord-005646-xhx9pzhj 3357 11 and and CC cord-005646-xhx9pzhj 3357 12 expressed express VBD cord-005646-xhx9pzhj 3357 13 as as IN cord-005646-xhx9pzhj 3357 14 the the DT cord-005646-xhx9pzhj 3357 15 percentage percentage NN cord-005646-xhx9pzhj 3357 16 of of IN cord-005646-xhx9pzhj 3357 17 the the DT cord-005646-xhx9pzhj 3357 18 total total JJ cord-005646-xhx9pzhj 3357 19 amount amount NN cord-005646-xhx9pzhj 3357 20 of of IN cord-005646-xhx9pzhj 3357 21 Teico Teico NNP cord-005646-xhx9pzhj 3357 22 prescribed prescribe VBN cord-005646-xhx9pzhj 3357 23 . . . cord-005646-xhx9pzhj 3358 1 A a DT cord-005646-xhx9pzhj 3358 2 2,8 2,8 CD cord-005646-xhx9pzhj 3358 3 % % NN cord-005646-xhx9pzhj 3358 4 6,4 6,4 CD cord-005646-xhx9pzhj 3358 5 % % NN cord-005646-xhx9pzhj 3358 6 B b NN cord-005646-xhx9pzhj 3358 7 47 47 CD cord-005646-xhx9pzhj 3358 8 % % NN cord-005646-xhx9pzhj 3358 9 62,3 62,3 CD cord-005646-xhx9pzhj 3358 10 % % NN cord-005646-xhx9pzhj 3358 11 C c NN cord-005646-xhx9pzhj 3358 12 82A 82a NN cord-005646-xhx9pzhj 3358 13 % % NN cord-005646-xhx9pzhj 3359 1 86,8 86,8 CD cord-005646-xhx9pzhj 3359 2 % % NN cord-005646-xhx9pzhj 3359 3 D d NN cord-005646-xhx9pzhj 3359 4 94,2 94,2 CD cord-005646-xhx9pzhj 3360 1 % % NN cord-005646-xhx9pzhj 3360 2 95 95 CD cord-005646-xhx9pzhj 3360 3 % % NN cord-005646-xhx9pzhj 3360 4 Conclusiom Conclusiom NNP cord-005646-xhx9pzhj 3360 5 for for IN cord-005646-xhx9pzhj 3360 6 accurate accurate JJ cord-005646-xhx9pzhj 3360 7 and and CC cord-005646-xhx9pzhj 3360 8 reliable reliable JJ cord-005646-xhx9pzhj 3360 9 intermittent intermittent JJ cord-005646-xhx9pzhj 3360 10 drug drug NN cord-005646-xhx9pzhj 3360 11 infusion infusion NN cord-005646-xhx9pzhj 3360 12 with with IN cord-005646-xhx9pzhj 3360 13 a a DT cord-005646-xhx9pzhj 3360 14 syringe syringe NN cord-005646-xhx9pzhj 3360 15 pump pump NN cord-005646-xhx9pzhj 3361 1 it -PRON- PRP cord-005646-xhx9pzhj 3361 2 is be VBZ cord-005646-xhx9pzhj 3361 3 mandatory mandatory JJ cord-005646-xhx9pzhj 3361 4 to to TO cord-005646-xhx9pzhj 3361 5 use use VB cord-005646-xhx9pzhj 3361 6 a a DT cord-005646-xhx9pzhj 3361 7 precise precise JJ cord-005646-xhx9pzhj 3361 8 protocol protocol NN cord-005646-xhx9pzhj 3361 9 of of IN cord-005646-xhx9pzhj 3361 10 administration administration NN cord-005646-xhx9pzhj 3361 11 and and CC cord-005646-xhx9pzhj 3361 12 to to TO cord-005646-xhx9pzhj 3361 13 take take VB cord-005646-xhx9pzhj 3361 14 in in IN cord-005646-xhx9pzhj 3361 15 account account NN cord-005646-xhx9pzhj 3361 16 1 1 CD cord-005646-xhx9pzhj 3361 17 ) ) -RRB- cord-005646-xhx9pzhj 3361 18 a a DT cord-005646-xhx9pzhj 3361 19 priming priming NN cord-005646-xhx9pzhj 3361 20 ( ( -LRB- cord-005646-xhx9pzhj 3361 21 for for IN cord-005646-xhx9pzhj 3361 22 immediate immediate JJ cord-005646-xhx9pzhj 3361 23 starting starting NN cord-005646-xhx9pzhj 3361 24 of of IN cord-005646-xhx9pzhj 3361 25 infusion infusion NN cord-005646-xhx9pzhj 3361 26 ) ) -RRB- cord-005646-xhx9pzhj 3361 27 , , , cord-005646-xhx9pzhj 3361 28 2 2 LS cord-005646-xhx9pzhj 3361 29 ) ) -RRB- cord-005646-xhx9pzhj 3361 30 a a DT cord-005646-xhx9pzhj 3361 31 drug drug NN cord-005646-xhx9pzhj 3361 32 volume volume NN cord-005646-xhx9pzhj 3361 33 greater great JJR cord-005646-xhx9pzhj 3361 34 than than IN cord-005646-xhx9pzhj 3361 35 the the DT cord-005646-xhx9pzhj 3361 36 dose dose NN cord-005646-xhx9pzhj 3361 37 prescribed prescribe VBN cord-005646-xhx9pzhj 3361 38 and and CC cord-005646-xhx9pzhj 3361 39 a a DT cord-005646-xhx9pzhj 3361 40 programmed program VBN cord-005646-xhx9pzhj 3361 41 volume volume NN cord-005646-xhx9pzhj 3361 42 injected inject VBN cord-005646-xhx9pzhj 3361 43 , , , cord-005646-xhx9pzhj 3361 44 3 3 CD cord-005646-xhx9pzhj 3361 45 ) ) -RRB- cord-005646-xhx9pzhj 3361 46 a a DT cord-005646-xhx9pzhj 3361 47 wash wash NN cord-005646-xhx9pzhj 3361 48 out out IN cord-005646-xhx9pzhj 3361 49 of of IN cord-005646-xhx9pzhj 3361 50 the the DT cord-005646-xhx9pzhj 3361 51 tubing tubing NN cord-005646-xhx9pzhj 3361 52 ( ( -LRB- cord-005646-xhx9pzhj 3361 53 with with IN cord-005646-xhx9pzhj 3361 54 a a DT cord-005646-xhx9pzhj 3361 55 volume volume NN cord-005646-xhx9pzhj 3361 56 ~ ~ NFP cord-005646-xhx9pzhj 3361 57 1,5 1,5 CD cord-005646-xhx9pzhj 3361 58 x x NN cord-005646-xhx9pzhj 3361 59 volume volume NN cord-005646-xhx9pzhj 3361 60 of of IN cord-005646-xhx9pzhj 3361 61 tubing tube VBG cord-005646-xhx9pzhj 3361 62 injection injection NN cord-005646-xhx9pzhj 3361 63 ) ) -RRB- cord-005646-xhx9pzhj 3362 1 CAZ CAZ NNP cord-005646-xhx9pzhj 3362 2 is be VBZ cord-005646-xhx9pzhj 3362 3 an an DT cord-005646-xhx9pzhj 3362 4 antibiotic antibiotic NN cord-005646-xhx9pzhj 3362 5 with with IN cord-005646-xhx9pzhj 3362 6 activity activity NN cord-005646-xhx9pzhj 3362 7 against against IN cord-005646-xhx9pzhj 3362 8 the the DT cord-005646-xhx9pzhj 3362 9 major major JJ cord-005646-xhx9pzhj 3362 10 pathogens pathogen NNS cord-005646-xhx9pzhj 3362 11 responsible responsible JJ cord-005646-xhx9pzhj 3362 12 for for IN cord-005646-xhx9pzhj 3362 13 neonatal neonatal JJ cord-005646-xhx9pzhj 3362 14 bacterial bacterial JJ cord-005646-xhx9pzhj 3362 15 infections infection NNS cord-005646-xhx9pzhj 3362 16 . . . cord-005646-xhx9pzhj 3363 1 We -PRON- PRP cord-005646-xhx9pzhj 3363 2 previously previously RB cord-005646-xhx9pzhj 3363 3 reported report VBD cord-005646-xhx9pzhj 3363 4 the the DT cord-005646-xhx9pzhj 3363 5 pharmacokinetics pharmacokinetic NNS cord-005646-xhx9pzhj 3363 6 of of IN cord-005646-xhx9pzhj 3363 7 CAZ CAZ NNP cord-005646-xhx9pzhj 3363 8 in in IN cord-005646-xhx9pzhj 3363 9 136 136 CD cord-005646-xhx9pzhj 3363 10 preterm preterm JJ cord-005646-xhx9pzhj 3363 11 infants infant NNS cord-005646-xhx9pzhj 3363 12 on on IN cord-005646-xhx9pzhj 3363 13 day day NN cord-005646-xhx9pzhj 3363 14 3 3 CD cord-005646-xhx9pzhj 3363 15 of of IN cord-005646-xhx9pzhj 3363 16 life life NN cord-005646-xhx9pzhj 3363 17 which which WDT cord-005646-xhx9pzhj 3363 18 showed show VBD cord-005646-xhx9pzhj 3363 19 that that IN cord-005646-xhx9pzhj 3363 20 the the DT cord-005646-xhx9pzhj 3363 21 clearance clearance NN cord-005646-xhx9pzhj 3363 22 of of IN cord-005646-xhx9pzhj 3363 23 CAZ CAZ NNP cord-005646-xhx9pzhj 3363 24 increased increase VBD cord-005646-xhx9pzhj 3363 25 with with IN cord-005646-xhx9pzhj 3363 26 increasing increase VBG cord-005646-xhx9pzhj 3363 27 gestationat gestationat NNP cord-005646-xhx9pzhj 3363 28 age age NN cord-005646-xhx9pzhj 3363 29 ( ( -LRB- cord-005646-xhx9pzhj 3363 30 GA GA NNP cord-005646-xhx9pzhj 3363 31 ) ) -RRB- cord-005646-xhx9pzhj 3363 32 . . . cord-005646-xhx9pzhj 3364 1 Mean mean JJ cord-005646-xhx9pzhj 3364 2 serum serum NN cord-005646-xhx9pzhj 3365 1 half half JJ cord-005646-xhx9pzhj 3365 2 - - HYPH cord-005646-xhx9pzhj 3365 3 life life NN cord-005646-xhx9pzhj 3365 4 of of IN cord-005646-xhx9pzhj 3365 5 infants infant NNS cord-005646-xhx9pzhj 3365 6 with with IN cord-005646-xhx9pzhj 3365 7 GAs gas NNS cord-005646-xhx9pzhj 3365 8 < < XX cord-005646-xhx9pzhj 3365 9 32 32 CD cord-005646-xhx9pzhj 3365 10 wks wks NN cord-005646-xhx9pzhj 3365 11 was be VBD cord-005646-xhx9pzhj 3365 12 8.7 8.7 CD cord-005646-xhx9pzhj 3365 13 h. h. NN cord-005646-xhx9pzhj 3366 1 We -PRON- PRP cord-005646-xhx9pzhj 3366 2 wanted want VBD cord-005646-xhx9pzhj 3366 3 to to TO cord-005646-xhx9pzhj 3366 4 investigate investigate VB cord-005646-xhx9pzhj 3366 5 the the DT cord-005646-xhx9pzhj 3366 6 effect effect NN cord-005646-xhx9pzhj 3366 7 of of IN cord-005646-xhx9pzhj 3366 8 postnatal postnatal JJ cord-005646-xhx9pzhj 3366 9 age age NN cord-005646-xhx9pzhj 3366 10 on on IN cord-005646-xhx9pzhj 3366 11 CAZ CAZ NNP cord-005646-xhx9pzhj 3366 12 pharmacokinetics pharmacokinetic NNS cord-005646-xhx9pzhj 3366 13 , , , cord-005646-xhx9pzhj 3366 14 We -PRON- PRP cord-005646-xhx9pzhj 3366 15 therefore therefore RB cord-005646-xhx9pzhj 3366 16 studied study VBD cord-005646-xhx9pzhj 3366 17 CAZ CAZ NNP cord-005646-xhx9pzhj 3366 18 pharmacokinetics pharmacokinetic NNS cord-005646-xhx9pzhj 3366 19 on on IN cord-005646-xhx9pzhj 3366 20 day day NN cord-005646-xhx9pzhj 3366 21 19 19 CD cord-005646-xhx9pzhj 3366 22 - - SYM cord-005646-xhx9pzhj 3366 23 21 21 CD cord-005646-xhx9pzhj 3366 24 of of IN cord-005646-xhx9pzhj 3366 25 life life NN cord-005646-xhx9pzhj 3366 26 in in IN cord-005646-xhx9pzhj 3366 27 10 10 CD cord-005646-xhx9pzhj 3366 28 preterm preterm JJ cord-005646-xhx9pzhj 3366 29 infants infant NNS cord-005646-xhx9pzhj 3366 30 with with IN cord-005646-xhx9pzhj 3366 31 GAs gas NNS cord-005646-xhx9pzhj 3366 32 < < XX cord-005646-xhx9pzhj 3366 33 32 32 CD cord-005646-xhx9pzhj 3366 34 wks wks NN cord-005646-xhx9pzhj 3366 35 . . . cord-005646-xhx9pzhj 3367 1 CAZ CAZ NNP cord-005646-xhx9pzhj 3367 2 ( ( -LRB- cord-005646-xhx9pzhj 3367 3 25 25 CD cord-005646-xhx9pzhj 3367 4 mg mg NNP cord-005646-xhx9pzhj 3367 5 / / SYM cord-005646-xhx9pzhj 3367 6 kg kg NNP cord-005646-xhx9pzhj 3367 7 ) ) -RRB- cord-005646-xhx9pzhj 3367 8 was be VBD cord-005646-xhx9pzhj 3367 9 administered administer VBN cord-005646-xhx9pzhj 3367 10 as as IN cord-005646-xhx9pzhj 3367 11 an an DT cord-005646-xhx9pzhj 3367 12 intravenous intravenous JJ cord-005646-xhx9pzhj 3367 13 bolus bolus NN cord-005646-xhx9pzhj 3367 14 injection injection NN cord-005646-xhx9pzhj 3367 15 . . . cord-005646-xhx9pzhj 3368 1 Blood blood NN cord-005646-xhx9pzhj 3368 2 samples sample NNS cord-005646-xhx9pzhj 3368 3 were be VBD cord-005646-xhx9pzhj 3368 4 coIlected coilecte VBN cord-005646-xhx9pzhj 3368 5 before before RB cord-005646-xhx9pzhj 3368 6 ( ( -LRB- cord-005646-xhx9pzhj 3368 7 t t NN cord-005646-xhx9pzhj 3368 8 = = SYM cord-005646-xhx9pzhj 3368 9 0 0 CD cord-005646-xhx9pzhj 3368 10 ) ) -RRB- cord-005646-xhx9pzhj 3368 11 , , , cord-005646-xhx9pzhj 3368 12 and and CC cord-005646-xhx9pzhj 3368 13 0.5,1,2,4,8 0.5,1,2,4,8 CD cord-005646-xhx9pzhj 3368 14 and and CC cord-005646-xhx9pzhj 3368 15 12 12 CD cord-005646-xhx9pzhj 3368 16 h h NN cord-005646-xhx9pzhj 3368 17 after after IN cord-005646-xhx9pzhj 3368 18 the the DT cord-005646-xhx9pzhj 3368 19 CAZ CAZ NNP cord-005646-xhx9pzhj 3368 20 dose dose NN cord-005646-xhx9pzhj 3368 21 and and CC cord-005646-xhx9pzhj 3368 22 analyzed analyze VBN cord-005646-xhx9pzhj 3368 23 by by IN cord-005646-xhx9pzhj 3368 24 HPLCassay HPLCassay NNP cord-005646-xhx9pzhj 3368 25 , , , cord-005646-xhx9pzhj 3368 26 The the DT cord-005646-xhx9pzhj 3368 27 pharmacokinetics pharmacokinetic NNS cord-005646-xhx9pzhj 3368 28 of of IN cord-005646-xhx9pzhj 3368 29 CAZ CAZ NNP cord-005646-xhx9pzhj 3368 30 followed follow VBD cord-005646-xhx9pzhj 3368 31 a a DT cord-005646-xhx9pzhj 3368 32 one one CD cord-005646-xhx9pzhj 3368 33 - - HYPH cord-005646-xhx9pzhj 3368 34 compartment compartment NN cord-005646-xhx9pzhj 3368 35 open open JJ cord-005646-xhx9pzhj 3368 36 model model NN cord-005646-xhx9pzhj 3368 37 . . . cord-005646-xhx9pzhj 3369 1 During during IN cord-005646-xhx9pzhj 3369 2 1995 1995 CD cord-005646-xhx9pzhj 3369 3 11 11 CD cord-005646-xhx9pzhj 3369 4 newborns newborn NNS cord-005646-xhx9pzhj 3369 5 with with IN cord-005646-xhx9pzhj 3369 6 complex complex JJ cord-005646-xhx9pzhj 3369 7 congenital congenital JJ cord-005646-xhx9pzhj 3369 8 heart heart NN cord-005646-xhx9pzhj 3369 9 defects defect NNS cord-005646-xhx9pzhj 3369 10 requiering requiere VBG cord-005646-xhx9pzhj 3369 11 either either CC cord-005646-xhx9pzhj 3369 12 HTX HTX NNP cord-005646-xhx9pzhj 3369 13 or or CC cord-005646-xhx9pzhj 3369 14 palliative palliative NN cord-005646-xhx9pzhj 3369 15 staged stage VBD cord-005646-xhx9pzhj 3369 16 single single JJ cord-005646-xhx9pzhj 3369 17 ventricle ventricle NN cord-005646-xhx9pzhj 3369 18 repair repair NN cord-005646-xhx9pzhj 3369 19 were be VBD cord-005646-xhx9pzhj 3369 20 admitted admit VBN cord-005646-xhx9pzhj 3369 21 to to IN cord-005646-xhx9pzhj 3369 22 our -PRON- PRP$ cord-005646-xhx9pzhj 3369 23 hospital hospital NN cord-005646-xhx9pzhj 3369 24 : : : cord-005646-xhx9pzhj 3369 25 HLH HLH NNP cord-005646-xhx9pzhj 3369 26 n=8 n=8 NN cord-005646-xhx9pzhj 3369 27 , , , cord-005646-xhx9pzhj 3369 28 unbalanced unbalanced JJ cord-005646-xhx9pzhj 3369 29 CAVSD CAVSD NNP cord-005646-xhx9pzhj 3369 30 , , , cord-005646-xhx9pzhj 3369 31 TGA TGA NNP cord-005646-xhx9pzhj 3369 32 with with IN cord-005646-xhx9pzhj 3369 33 hypopl hypopl NN cord-005646-xhx9pzhj 3369 34 . . . cord-005646-xhx9pzhj 3370 1 RV rv NN cord-005646-xhx9pzhj 3370 2 and and CC cord-005646-xhx9pzhj 3370 3 hypoplastic hypoplastic JJ cord-005646-xhx9pzhj 3370 4 AOA AOA NNP cord-005646-xhx9pzhj 3370 5 . . . cord-005646-xhx9pzhj 3371 1 TGA TGA NNP cord-005646-xhx9pzhj 3371 2 with with IN cord-005646-xhx9pzhj 3371 3 hypopl hypopl NN cord-005646-xhx9pzhj 3371 4 . . . cord-005646-xhx9pzhj 3372 1 RV RV NNP cord-005646-xhx9pzhj 3372 2 , , , cord-005646-xhx9pzhj 3372 3 SAS SAS NNP cord-005646-xhx9pzhj 3372 4 and and CC cord-005646-xhx9pzhj 3372 5 dextrocardia dextrocardia NNS cord-005646-xhx9pzhj 3372 6 . . . cord-005646-xhx9pzhj 3373 1 8/ 8/ CD cord-005646-xhx9pzhj 3374 1 I -PRON- PRP cord-005646-xhx9pzhj 3374 2 1 1 CD cord-005646-xhx9pzhj 3374 3 children child NNS cord-005646-xhx9pzhj 3374 4 had have VBD cord-005646-xhx9pzhj 3374 5 been be VBN cord-005646-xhx9pzhj 3374 6 admitted admit VBN cord-005646-xhx9pzhj 3374 7 with with IN cord-005646-xhx9pzhj 3374 8 cardiogenic cardiogenic JJ cord-005646-xhx9pzhj 3374 9 shuck shuck NN cord-005646-xhx9pzhj 3374 10 and and CC cord-005646-xhx9pzhj 3374 11 mukiorgan mukiorgan NN cord-005646-xhx9pzhj 3374 12 failure failure NN cord-005646-xhx9pzhj 3374 13 due due IN cord-005646-xhx9pzhj 3374 14 to to IN cord-005646-xhx9pzhj 3374 15 intermittend intermittend JJ cord-005646-xhx9pzhj 3374 16 closure closure NN cord-005646-xhx9pzhj 3374 17 ofDuctus ofDuctus NNP cord-005646-xhx9pzhj 3374 18 arteriosus arteriosus NN cord-005646-xhx9pzhj 3374 19 ; ; : cord-005646-xhx9pzhj 3374 20 in in IN cord-005646-xhx9pzhj 3374 21 3/8 3/8 CD cord-005646-xhx9pzhj 3374 22 stabilization stabilization NN cord-005646-xhx9pzhj 3374 23 failed fail VBD cord-005646-xhx9pzhj 3374 24 . . . cord-005646-xhx9pzhj 3375 1 Parents parent NNS cord-005646-xhx9pzhj 3375 2 were be VBD cord-005646-xhx9pzhj 3375 3 informed inform VBN cord-005646-xhx9pzhj 3375 4 about about IN cord-005646-xhx9pzhj 3375 5 the the DT cord-005646-xhx9pzhj 3375 6 known known JJ cord-005646-xhx9pzhj 3375 7 and and CC cord-005646-xhx9pzhj 3375 8 unknown unknown JJ cord-005646-xhx9pzhj 3375 9 risks risk NNS cord-005646-xhx9pzhj 3375 10 of of IN cord-005646-xhx9pzhj 3375 11 the the DT cord-005646-xhx9pzhj 3375 12 always always RB cord-005646-xhx9pzhj 3375 13 palliative palliative JJ cord-005646-xhx9pzhj 3375 14 surgery surgery NN cord-005646-xhx9pzhj 3375 15 ; ; : cord-005646-xhx9pzhj 3375 16 in in IN cord-005646-xhx9pzhj 3375 17 2 2 CD cord-005646-xhx9pzhj 3375 18 cases case NNS cord-005646-xhx9pzhj 3375 19 parents parent NNS cord-005646-xhx9pzhj 3375 20 denied deny VBD cord-005646-xhx9pzhj 3375 21 further further JJ cord-005646-xhx9pzhj 3375 22 therapy therapy NN cord-005646-xhx9pzhj 3375 23 . . . cord-005646-xhx9pzhj 3376 1 One one CD cord-005646-xhx9pzhj 3376 2 pafiem pafiem NN cord-005646-xhx9pzhj 3376 3 with with IN cord-005646-xhx9pzhj 3376 4 HLH HLH NNP cord-005646-xhx9pzhj 3376 5 underwent undergo VBD cord-005646-xhx9pzhj 3376 6 orthotopic orthotopic NNP cord-005646-xhx9pzhj 3376 7 HTX HTX NNP cord-005646-xhx9pzhj 3376 8 at at IN cord-005646-xhx9pzhj 3376 9 the the DT cord-005646-xhx9pzhj 3376 10 age age NN cord-005646-xhx9pzhj 3376 11 of of IN cord-005646-xhx9pzhj 3376 12 5 5 CD cord-005646-xhx9pzhj 3376 13 month month NN cord-005646-xhx9pzhj 3376 14 after after IN cord-005646-xhx9pzhj 3376 15 the the DT cord-005646-xhx9pzhj 3376 16 Ducms Ducms NNP cord-005646-xhx9pzhj 3376 17 art art NN cord-005646-xhx9pzhj 3376 18 . . . cord-005646-xhx9pzhj 3377 1 had have VBD cord-005646-xhx9pzhj 3377 2 been be VBN cord-005646-xhx9pzhj 3377 3 stunted stunt VBN cord-005646-xhx9pzhj 3377 4 in in IN cord-005646-xhx9pzhj 3377 5 the the DT cord-005646-xhx9pzhj 3377 6 newborn newborn JJ cord-005646-xhx9pzhj 3377 7 period period NN cord-005646-xhx9pzhj 3377 8 . . . cord-005646-xhx9pzhj 3378 1 9 9 CD cord-005646-xhx9pzhj 3378 2 month month NN cord-005646-xhx9pzhj 3378 3 later later RBR cord-005646-xhx9pzhj 3378 4 he -PRON- PRP cord-005646-xhx9pzhj 3378 5 is be VBZ cord-005646-xhx9pzhj 3378 6 still still RB cord-005646-xhx9pzhj 3378 7 in in IN cord-005646-xhx9pzhj 3378 8 favourable favourable JJ cord-005646-xhx9pzhj 3378 9 condition condition NN cord-005646-xhx9pzhj 3378 10 and and CC cord-005646-xhx9pzhj 3378 11 without without IN cord-005646-xhx9pzhj 3378 12 any any DT cord-005646-xhx9pzhj 3378 13 sign sign NN cord-005646-xhx9pzhj 3378 14 of of IN cord-005646-xhx9pzhj 3378 15 acute acute JJ cord-005646-xhx9pzhj 3378 16 organ organ NN cord-005646-xhx9pzhj 3378 17 rejection rejection NN cord-005646-xhx9pzhj 3378 18 . . . cord-005646-xhx9pzhj 3379 1 5/11 5/11 CD cord-005646-xhx9pzhj 3379 2 underwent undergo VBD cord-005646-xhx9pzhj 3379 3 first first JJ cord-005646-xhx9pzhj 3379 4 stage stage NN cord-005646-xhx9pzhj 3379 5 of of IN cord-005646-xhx9pzhj 3379 6 paLliative paLliative NNP cord-005646-xhx9pzhj 3379 7 single single JJ cord-005646-xhx9pzhj 3379 8 ventricle ventricle NN cord-005646-xhx9pzhj 3379 9 repair repair NN cord-005646-xhx9pzhj 3379 10 : : : cord-005646-xhx9pzhj 3380 1 Norwood Norwood NNP cord-005646-xhx9pzhj 3380 2 -Op -op IN cord-005646-xhx9pzhj 3380 3 . . . cord-005646-xhx9pzhj 3381 1 ( ( -LRB- cord-005646-xhx9pzhj 3381 2 3 3 LS cord-005646-xhx9pzhj 3381 3 ) ) -RRB- cord-005646-xhx9pzhj 3381 4 ( ( -LRB- cord-005646-xhx9pzhj 3381 5 n=3 n=3 NN cord-005646-xhx9pzhj 3381 6 ) ) -RRB- cord-005646-xhx9pzhj 3381 7 , , , cord-005646-xhx9pzhj 3381 8 Damus Damus NNP cord-005646-xhx9pzhj 3381 9 - - HYPH cord-005646-xhx9pzhj 3381 10 Kaye Kaye NNP cord-005646-xhx9pzhj 3381 11 - - HYPH cord-005646-xhx9pzhj 3381 12 Stansel Stansel NNP cord-005646-xhx9pzhj 3382 1 -Procedure -Procedure NFP cord-005646-xhx9pzhj 3382 2 ( ( -LRB- cord-005646-xhx9pzhj 3382 3 2 2 CD cord-005646-xhx9pzhj 3382 4 ) ) -RRB- cord-005646-xhx9pzhj 3382 5 . . . cord-005646-xhx9pzhj 3383 1 The the DT cord-005646-xhx9pzhj 3383 2 clue clue NN cord-005646-xhx9pzhj 3383 3 to to TO cord-005646-xhx9pzhj 3383 4 adequate adequate VB cord-005646-xhx9pzhj 3383 5 postoperative postoperative JJ cord-005646-xhx9pzhj 3383 6 management management NN cord-005646-xhx9pzhj 3383 7 was be VBD cord-005646-xhx9pzhj 3383 8 to to TO cord-005646-xhx9pzhj 3383 9 archieve archieve VB cord-005646-xhx9pzhj 3383 10 a a DT cord-005646-xhx9pzhj 3383 11 balanced balanced JJ cord-005646-xhx9pzhj 3383 12 distribution distribution NN cord-005646-xhx9pzhj 3383 13 of of IN cord-005646-xhx9pzhj 3383 14 flow flow NN cord-005646-xhx9pzhj 3383 15 to to IN cord-005646-xhx9pzhj 3383 16 systemic systemic JJ cord-005646-xhx9pzhj 3383 17 and and CC cord-005646-xhx9pzhj 3383 18 pulm pulm NN cord-005646-xhx9pzhj 3383 19 circulation circulation NN cord-005646-xhx9pzhj 3383 20 , , , cord-005646-xhx9pzhj 3383 21 that that DT cord-005646-xhx9pzhj 3383 22 is be VBZ cord-005646-xhx9pzhj 3383 23 to to TO cord-005646-xhx9pzhj 3383 24 protect protect VB cord-005646-xhx9pzhj 3383 25 the the DT cord-005646-xhx9pzhj 3383 26 single single JJ cord-005646-xhx9pzhj 3383 27 ventricle ventricle NN cord-005646-xhx9pzhj 3383 28 from from IN cord-005646-xhx9pzhj 3383 29 volume volume NN cord-005646-xhx9pzhj 3383 30 overload overload NN cord-005646-xhx9pzhj 3383 31 and and CC cord-005646-xhx9pzhj 3383 32 to to TO cord-005646-xhx9pzhj 3383 33 guarantee guarantee VB cord-005646-xhx9pzhj 3383 34 sufficient sufficient JJ cord-005646-xhx9pzhj 3383 35 oxygenation oxygenation NN cord-005646-xhx9pzhj 3383 36 and and CC cord-005646-xhx9pzhj 3383 37 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3383 38 development development NN cord-005646-xhx9pzhj 3383 39 as as RB cord-005646-xhx9pzhj 3383 40 well well RB cord-005646-xhx9pzhj 3383 41 . . . cord-005646-xhx9pzhj 3384 1 With with IN cord-005646-xhx9pzhj 3384 2 the the DT cord-005646-xhx9pzhj 3384 3 centralvenous centralvenous JJ cord-005646-xhx9pzhj 3384 4 SatO2 SatO2 NNP cord-005646-xhx9pzhj 3384 5 at at IN cord-005646-xhx9pzhj 3384 6 about about RB cord-005646-xhx9pzhj 3384 7 50 50 CD cord-005646-xhx9pzhj 3384 8 % % NN cord-005646-xhx9pzhj 3384 9 provided provide VBN cord-005646-xhx9pzhj 3384 10 maintaining maintain VBG cord-005646-xhx9pzhj 3384 11 the the DT cord-005646-xhx9pzhj 3384 12 arterial arterial JJ cord-005646-xhx9pzhj 3384 13 SatO2 SatO2 NNP cord-005646-xhx9pzhj 3384 14 at at IN cord-005646-xhx9pzhj 3384 15 about about IN cord-005646-xhx9pzhj 3384 16 75_+5 75_+5 CD cord-005646-xhx9pzhj 3384 17 % % NN cord-005646-xhx9pzhj 3384 18 is be VBZ cord-005646-xhx9pzhj 3384 19 corresponding correspond VBG cord-005646-xhx9pzhj 3384 20 with with IN cord-005646-xhx9pzhj 3384 21 a a DT cord-005646-xhx9pzhj 3384 22 Qp Qp NNP cord-005646-xhx9pzhj 3384 23 / / SYM cord-005646-xhx9pzhj 3384 24 Qs Qs NNP cord-005646-xhx9pzhj 3384 25 of of IN cord-005646-xhx9pzhj 3384 26 1:1 1:1 CD cord-005646-xhx9pzhj 3384 27 . . . cord-005646-xhx9pzhj 3385 1 Using use VBG cord-005646-xhx9pzhj 3385 2 modified modify VBN cord-005646-xhx9pzhj 3385 3 BT BT NNP cord-005646-xhx9pzhj 3385 4 - - HYPH cord-005646-xhx9pzhj 3385 5 shunts shunt NNS cord-005646-xhx9pzhj 3385 6 of3.5 of3.5 NN cord-005646-xhx9pzhj 3385 7 mm mm NN cord-005646-xhx9pzhj 3385 8 resp resp NNP cord-005646-xhx9pzhj 3385 9 . . . cord-005646-xhx9pzhj 3386 1 a a DT cord-005646-xhx9pzhj 3386 2 central central JJ cord-005646-xhx9pzhj 3386 3 anrtopulm anrtopulm NNS cord-005646-xhx9pzhj 3386 4 , , , cord-005646-xhx9pzhj 3386 5 shunt shunt NN cord-005646-xhx9pzhj 3386 6 of of IN cord-005646-xhx9pzhj 3386 7 4 4 CD cord-005646-xhx9pzhj 3386 8 mm mm NNS cord-005646-xhx9pzhj 3386 9 in in IN cord-005646-xhx9pzhj 3386 10 one one CD cord-005646-xhx9pzhj 3386 11 case case NN cord-005646-xhx9pzhj 3386 12 l l NN cord-005646-xhx9pzhj 3386 13 severe severe JJ cord-005646-xhx9pzhj 3386 14 puim puim NNP cord-005646-xhx9pzhj 3386 15 . . . cord-005646-xhx9pzhj 3387 1 hypertension hypertension NN cord-005646-xhx9pzhj 3387 2 , , , cord-005646-xhx9pzhj 3387 3 surgery surgery NN cord-005646-xhx9pzhj 3387 4 at at IN cord-005646-xhx9pzhj 3387 5 6 6 CD cord-005646-xhx9pzhj 3387 6 weeks week NNS cord-005646-xhx9pzhj 3387 7 of of IN cord-005646-xhx9pzhj 3387 8 age age NN cord-005646-xhx9pzhj 3387 9 ) ) -RRB- cord-005646-xhx9pzhj 3387 10 there there EX cord-005646-xhx9pzhj 3387 11 was be VBD cord-005646-xhx9pzhj 3387 12 no no DT cord-005646-xhx9pzhj 3387 13 excessive excessive JJ cord-005646-xhx9pzhj 3387 14 pulm pulm NN cord-005646-xhx9pzhj 3387 15 . . . cord-005646-xhx9pzhj 3388 1 blood blood NN cord-005646-xhx9pzhj 3388 2 flow flow NN cord-005646-xhx9pzhj 3388 3 and and CC cord-005646-xhx9pzhj 3388 4 no no DT cord-005646-xhx9pzhj 3388 5 need need NN cord-005646-xhx9pzhj 3388 6 to to TO cord-005646-xhx9pzhj 3388 7 increase increase VB cord-005646-xhx9pzhj 3388 8 PVR PVR NNP cord-005646-xhx9pzhj 3388 9 with with IN cord-005646-xhx9pzhj 3388 10 inspired inspire VBN cord-005646-xhx9pzhj 3388 11 CO2 CO2 NNP cord-005646-xhx9pzhj 3388 12 . . . cord-005646-xhx9pzhj 3389 1 One one CD cord-005646-xhx9pzhj 3389 2 child child NN cord-005646-xhx9pzhj 3389 3 ( ( -LRB- cord-005646-xhx9pzhj 3389 4 Norwood Norwood NNP cord-005646-xhx9pzhj 3389 5 at at IN cord-005646-xhx9pzhj 3389 6 5 5 CD cord-005646-xhx9pzhj 3389 7 weeks week NNS cord-005646-xhx9pzhj 3389 8 , , , cord-005646-xhx9pzhj 3389 9 preexisting preexist VBG cord-005646-xhx9pzhj 3389 10 pnim pnim NNS cord-005646-xhx9pzhj 3389 11 _ _ NNP cord-005646-xhx9pzhj 3389 12 edema edema NN cord-005646-xhx9pzhj 3389 13 ) ) -RRB- cord-005646-xhx9pzhj 3389 14 developed develop VBD cord-005646-xhx9pzhj 3389 15 severe severe JJ cord-005646-xhx9pzhj 3389 16 pulur pulur NN cord-005646-xhx9pzhj 3389 17 hypertension hypertension NN cord-005646-xhx9pzhj 3389 18 and and CC cord-005646-xhx9pzhj 3389 19 parenchymal parenchymal NNP cord-005646-xhx9pzhj 3389 20 pulm pulm NN cord-005646-xhx9pzhj 3389 21 . . . cord-005646-xhx9pzhj 3390 1 dysfunction dysfunction NN cord-005646-xhx9pzhj 3390 2 after after IN cord-005646-xhx9pzhj 3390 3 prolonged prolong VBN cord-005646-xhx9pzhj 3390 4 bypass bypass NN cord-005646-xhx9pzhj 3390 5 and and CC cord-005646-xhx9pzhj 3390 6 multiple multiple JJ cord-005646-xhx9pzhj 3390 7 transfusions transfusion NNS cord-005646-xhx9pzhj 3390 8 due due JJ cord-005646-xhx9pzhj 3390 9 to to IN cord-005646-xhx9pzhj 3390 10 intraoperative intraoperative JJ cord-005646-xhx9pzhj 3390 11 bleeding bleeding NN cord-005646-xhx9pzhj 3390 12 : : : cord-005646-xhx9pzhj 3390 13 hypoxemia hypoxemia NN cord-005646-xhx9pzhj 3390 14 could could MD cord-005646-xhx9pzhj 3390 15 be be VB cord-005646-xhx9pzhj 3390 16 managed manage VBN cord-005646-xhx9pzhj 3390 17 successfully successfully RB cord-005646-xhx9pzhj 3390 18 by by IN cord-005646-xhx9pzhj 3390 19 implanting implant VBG cord-005646-xhx9pzhj 3390 20 a a DT cord-005646-xhx9pzhj 3390 21 second second JJ cord-005646-xhx9pzhj 3390 22 shunt shunt NN cord-005646-xhx9pzhj 3390 23 of4 of4 NNS cord-005646-xhx9pzhj 3390 24 mm mm NNP cord-005646-xhx9pzhj 3390 25 18hh 18hh NN cord-005646-xhx9pzhj 3390 26 later later RB cord-005646-xhx9pzhj 3390 27 and and CC cord-005646-xhx9pzhj 3390 28 temporarily temporarily RB cord-005646-xhx9pzhj 3390 29 using use VBG cord-005646-xhx9pzhj 3390 30 Prostacyclin Prostacyclin NNP cord-005646-xhx9pzhj 3390 31 and and CC cord-005646-xhx9pzhj 3390 32 NO NO NNP cord-005646-xhx9pzhj 3390 33 ; ; : cord-005646-xhx9pzhj 3390 34 at at IN cord-005646-xhx9pzhj 3390 35 sternum sternum NN cord-005646-xhx9pzhj 3390 36 closure closure NN cord-005646-xhx9pzhj 3390 37 6 6 CD cord-005646-xhx9pzhj 3390 38 dd dd NN cord-005646-xhx9pzhj 3390 39 later later RB cord-005646-xhx9pzhj 3390 40 the the DT cord-005646-xhx9pzhj 3390 41 second second JJ cord-005646-xhx9pzhj 3390 42 shtmt shtmt NNP cord-005646-xhx9pzhj 3390 43 was be VBD cord-005646-xhx9pzhj 3390 44 banded band VBN cord-005646-xhx9pzhj 3390 45 to to IN cord-005646-xhx9pzhj 3390 46 3ram 3ram CD cord-005646-xhx9pzhj 3390 47 . . . cord-005646-xhx9pzhj 3391 1 Follow follow VB cord-005646-xhx9pzhj 3391 2 - - HYPH cord-005646-xhx9pzhj 3391 3 up up NN cord-005646-xhx9pzhj 3391 4 ranges range VBZ cord-005646-xhx9pzhj 3391 5 5 5 CD cord-005646-xhx9pzhj 3391 6 - - SYM cord-005646-xhx9pzhj 3391 7 5 5 CD cord-005646-xhx9pzhj 3391 8 month month NN cord-005646-xhx9pzhj 3392 1 : : : cord-005646-xhx9pzhj 3392 2 all all DT cord-005646-xhx9pzhj 3392 3 5 5 CD cord-005646-xhx9pzhj 3392 4 children child NNS cord-005646-xhx9pzhj 3392 5 are be VBP cord-005646-xhx9pzhj 3392 6 at at IN cord-005646-xhx9pzhj 3392 7 home home NN cord-005646-xhx9pzhj 3392 8 being be VBG cord-005646-xhx9pzhj 3392 9 assigned assign VBN cord-005646-xhx9pzhj 3392 10 for for IN cord-005646-xhx9pzhj 3392 11 second second JJ cord-005646-xhx9pzhj 3392 12 stage stage NN cord-005646-xhx9pzhj 3392 13 operation operation NN cord-005646-xhx9pzhj 3392 14 at at IN cord-005646-xhx9pzhj 3392 15 about about RB cord-005646-xhx9pzhj 3392 16 6 6 CD cord-005646-xhx9pzhj 3392 17 month month NN cord-005646-xhx9pzhj 3392 18 of of IN cord-005646-xhx9pzhj 3392 19 age age NN cord-005646-xhx9pzhj 3392 20 . . . cord-005646-xhx9pzhj 3393 1 Establishing establish VBG cord-005646-xhx9pzhj 3393 2 clinical clinical JJ cord-005646-xhx9pzhj 3393 3 practice practice NN cord-005646-xhx9pzhj 3393 4 guidelines guideline NNS cord-005646-xhx9pzhj 3393 5 has have VBZ cord-005646-xhx9pzhj 3393 6 become become VBN cord-005646-xhx9pzhj 3393 7 increasingly increasingly RB cord-005646-xhx9pzhj 3393 8 important important JJ cord-005646-xhx9pzhj 3393 9 in in IN cord-005646-xhx9pzhj 3393 10 the the DT cord-005646-xhx9pzhj 3393 11 current current JJ cord-005646-xhx9pzhj 3393 12 health health NN cord-005646-xhx9pzhj 3393 13 care care NN cord-005646-xhx9pzhj 3393 14 environment environment NN cord-005646-xhx9pzhj 3393 15 . . . cord-005646-xhx9pzhj 3394 1 Significant significant JJ cord-005646-xhx9pzhj 3394 2 effort effort NN cord-005646-xhx9pzhj 3394 3 has have VBZ cord-005646-xhx9pzhj 3394 4 been be VBN cord-005646-xhx9pzhj 3394 5 focused focus VBN cord-005646-xhx9pzhj 3394 6 upon upon IN cord-005646-xhx9pzhj 3394 7 development development NN cord-005646-xhx9pzhj 3394 8 of of IN cord-005646-xhx9pzhj 3394 9 post post JJ cord-005646-xhx9pzhj 3394 10 - - JJ cord-005646-xhx9pzhj 3394 11 operetive operetive JJ cord-005646-xhx9pzhj 3394 12 critical critical JJ cord-005646-xhx9pzhj 3394 13 care care NN cord-005646-xhx9pzhj 3394 14 pathways pathway NNS cord-005646-xhx9pzhj 3394 15 . . . cord-005646-xhx9pzhj 3395 1 However however RB cord-005646-xhx9pzhj 3395 2 , , , cord-005646-xhx9pzhj 3395 3 benchmark benchmark JJ cord-005646-xhx9pzhj 3395 4 data datum NNS cord-005646-xhx9pzhj 3395 5 upon upon IN cord-005646-xhx9pzhj 3395 6 which which WDT cord-005646-xhx9pzhj 3395 7 such such JJ cord-005646-xhx9pzhj 3395 8 pathways pathway NNS cord-005646-xhx9pzhj 3395 9 should should MD cord-005646-xhx9pzhj 3395 10 be be VB cord-005646-xhx9pzhj 3395 11 based base VBN cord-005646-xhx9pzhj 3395 12 has have VBZ cord-005646-xhx9pzhj 3395 13 not not RB cord-005646-xhx9pzhj 3395 14 been be VBN cord-005646-xhx9pzhj 3395 15 well well RB cord-005646-xhx9pzhj 3395 16 reported report VBN cord-005646-xhx9pzhj 3395 17 . . . cord-005646-xhx9pzhj 3396 1 Length length NN cord-005646-xhx9pzhj 3396 2 of of IN cord-005646-xhx9pzhj 3396 3 mechanical mechanical JJ cord-005646-xhx9pzhj 3396 4 ventilation ventilation NN cord-005646-xhx9pzhj 3396 5 ( ( -LRB- cord-005646-xhx9pzhj 3396 6 LMV LMV NNP cord-005646-xhx9pzhj 3396 7 ) ) -RRB- cord-005646-xhx9pzhj 3396 8 and and CC cord-005646-xhx9pzhj 3396 9 length length NN cord-005646-xhx9pzhj 3396 10 of of IN cord-005646-xhx9pzhj 3396 11 stay stay NN cord-005646-xhx9pzhj 3396 12 ( ( -LRB- cord-005646-xhx9pzhj 3396 13 LOS LOS NNP cord-005646-xhx9pzhj 3396 14 ) ) -RRB- cord-005646-xhx9pzhj 3396 15 for for IN cord-005646-xhx9pzhj 3396 16 children child NNS cord-005646-xhx9pzhj 3396 17 following follow VBG cord-005646-xhx9pzhj 3396 18 cardiac cardiac JJ cord-005646-xhx9pzhj 3396 19 surgery surgery NN cord-005646-xhx9pzhj 3396 20 , , , cord-005646-xhx9pzhj 3396 21 for for IN cord-005646-xhx9pzhj 3396 22 example example NN cord-005646-xhx9pzhj 3396 23 , , , cord-005646-xhx9pzhj 3396 24 is be VBZ cord-005646-xhx9pzhj 3396 25 poorly poorly RB cord-005646-xhx9pzhj 3396 26 described describe VBN cord-005646-xhx9pzhj 3396 27 . . . cord-005646-xhx9pzhj 3397 1 We -PRON- PRP cord-005646-xhx9pzhj 3397 2 prospectively prospectively RB cord-005646-xhx9pzhj 3397 3 recorded record VBD cord-005646-xhx9pzhj 3397 4 the the DT cord-005646-xhx9pzhj 3397 5 LMV LMV NNP cord-005646-xhx9pzhj 3397 6 and and CC cord-005646-xhx9pzhj 3397 7 LOS LOS NNP cord-005646-xhx9pzhj 3397 8 in in IN cord-005646-xhx9pzhj 3397 9 168 168 CD cord-005646-xhx9pzhj 3397 10 patients patient NNS cord-005646-xhx9pzhj 3397 11 who who WP cord-005646-xhx9pzhj 3397 12 underwent undergo VBD cord-005646-xhx9pzhj 3397 13 cardiothoracic cardiothoracic JJ cord-005646-xhx9pzhj 3397 14 surgery surgery NN cord-005646-xhx9pzhj 3397 15 between between IN cord-005646-xhx9pzhj 3397 16 9/1/93 9/1/93 CD cord-005646-xhx9pzhj 3397 17 to to IN cord-005646-xhx9pzhj 3397 18 6/30/95 6/30/95 CD cord-005646-xhx9pzhj 3397 19 . . . cord-005646-xhx9pzhj 3398 1 Only only RB cord-005646-xhx9pzhj 3398 2 patients patient NNS cord-005646-xhx9pzhj 3398 3 who who WP cord-005646-xhx9pzhj 3398 4 belonged belong VBD cord-005646-xhx9pzhj 3398 5 in in IN cord-005646-xhx9pzhj 3398 6 any any DT cord-005646-xhx9pzhj 3398 7 one one CD cord-005646-xhx9pzhj 3398 8 of of IN cord-005646-xhx9pzhj 3398 9 five five CD cord-005646-xhx9pzhj 3398 10 categories category NNS cord-005646-xhx9pzhj 3398 11 of of IN cord-005646-xhx9pzhj 3398 12 congenital congenital JJ cord-005646-xhx9pzhj 3398 13 heart heart NN cord-005646-xhx9pzhj 3398 14 disease disease NN cord-005646-xhx9pzhj 3398 15 ( ( -LRB- cord-005646-xhx9pzhj 3398 16 ventricular ventricular JJ cord-005646-xhx9pzhj 3398 17 septal septal JJ cord-005646-xhx9pzhj 3398 18 defect defect NN cord-005646-xhx9pzhj 3399 1 _ _ NNP cord-005646-xhx9pzhj 3400 1 + + CC cord-005646-xhx9pzhj 3400 2 other other JJ cord-005646-xhx9pzhj 3400 3 septal septal JJ cord-005646-xhx9pzhj 3400 4 defects defect NNS cord-005646-xhx9pzhj 3400 5 ( ( -LRB- cord-005646-xhx9pzhj 3400 6 VSD VSD NNP cord-005646-xhx9pzhj 3400 7 ) ) -RRB- cord-005646-xhx9pzhj 3400 8 , , , cord-005646-xhx9pzhj 3400 9 atrioventricular atrioventricular JJ cord-005646-xhx9pzhj 3400 10 ( ( -LRB- cord-005646-xhx9pzhj 3400 11 AV AV NNP cord-005646-xhx9pzhj 3400 12 ) ) -RRB- cord-005646-xhx9pzhj 3400 13 canal canal NN cord-005646-xhx9pzhj 3400 14 , , , cord-005646-xhx9pzhj 3400 15 Tetralogy Tetralogy NNP cord-005646-xhx9pzhj 3400 16 of of IN cord-005646-xhx9pzhj 3400 17 Fallot Fallot NNP cord-005646-xhx9pzhj 3400 18 ( ( -LRB- cord-005646-xhx9pzhj 3400 19 TOF TOF NNP cord-005646-xhx9pzhj 3400 20 ) ) -RRB- cord-005646-xhx9pzhj 3400 21 , , , cord-005646-xhx9pzhj 3400 22 transposition transposition NN cord-005646-xhx9pzhj 3400 23 of of IN cord-005646-xhx9pzhj 3400 24 great great JJ cord-005646-xhx9pzhj 3400 25 arteries artery NNS cord-005646-xhx9pzhj 3400 26 ( ( -LRB- cord-005646-xhx9pzhj 3400 27 TGA TGA NNP cord-005646-xhx9pzhj 3400 28 ) ) -RRB- cord-005646-xhx9pzhj 3400 29 , , , cord-005646-xhx9pzhj 3400 30 and and CC cord-005646-xhx9pzhj 3400 31 single single JJ cord-005646-xhx9pzhj 3400 32 ventricle ventricle NN cord-005646-xhx9pzhj 3400 33 physiology physiology NN cord-005646-xhx9pzhj 3400 34 ( ( -LRB- cord-005646-xhx9pzhj 3400 35 Fontan Fontan NNP cord-005646-xhx9pzhj 3400 36 ) ) -RRB- cord-005646-xhx9pzhj 3400 37 ) ) -RRB- cord-005646-xhx9pzhj 3400 38 were be VBD cord-005646-xhx9pzhj 3400 39 included include VBN cord-005646-xhx9pzhj 3400 40 . . . cord-005646-xhx9pzhj 3401 1 Eight eight CD cord-005646-xhx9pzhj 3401 2 non non JJ cord-005646-xhx9pzhj 3401 3 - - NNS cord-005646-xhx9pzhj 3401 4 survivors survivor NNS cord-005646-xhx9pzhj 3401 5 were be VBD cord-005646-xhx9pzhj 3401 6 excluded exclude VBN cord-005646-xhx9pzhj 3401 7 from from IN cord-005646-xhx9pzhj 3401 8 the the DT cord-005646-xhx9pzhj 3401 9 analysis analysis NN cord-005646-xhx9pzhj 3401 10 . . . cord-005646-xhx9pzhj 3402 1 All all DT cord-005646-xhx9pzhj 3402 2 patients patient NNS cord-005646-xhx9pzhj 3402 3 were be VBD cord-005646-xhx9pzhj 3402 4 admitted admit VBN cord-005646-xhx9pzhj 3402 5 to to IN cord-005646-xhx9pzhj 3402 6 an an DT cord-005646-xhx9pzhj 3402 7 Intensive Intensive NNP cord-005646-xhx9pzhj 3402 8 Care Care NNP cord-005646-xhx9pzhj 3402 9 Unit Unit NNP cord-005646-xhx9pzhj 3402 10 0CU 0cu CD cord-005646-xhx9pzhj 3402 11 ) ) -RRB- cord-005646-xhx9pzhj 3403 1 post post VB cord-005646-xhx9pzhj 3403 2 - - JJ cord-005646-xhx9pzhj 3403 3 operatively operatively RB cord-005646-xhx9pzhj 3403 4 where where WRB cord-005646-xhx9pzhj 3403 5 mechanical mechanical JJ cord-005646-xhx9pzhj 3403 6 ventilation ventilation NN cord-005646-xhx9pzhj 3403 7 was be VBD cord-005646-xhx9pzhj 3403 8 managed manage VBN cord-005646-xhx9pzhj 3403 9 by by IN cord-005646-xhx9pzhj 3403 10 4 4 CD cord-005646-xhx9pzhj 3403 11 pediatric pediatric JJ cord-005646-xhx9pzhj 3403 12 intensivists intensivist NNS cord-005646-xhx9pzhj 3403 13 . . . cord-005646-xhx9pzhj 3404 1 LMV LMV NNP cord-005646-xhx9pzhj 3404 2 was be VBD cord-005646-xhx9pzhj 3404 3 defined define VBN cord-005646-xhx9pzhj 3404 4 as as IN cord-005646-xhx9pzhj 3404 5 the the DT cord-005646-xhx9pzhj 3404 6 period period NN cord-005646-xhx9pzhj 3404 7 from from IN cord-005646-xhx9pzhj 3404 8 post post JJ cord-005646-xhx9pzhj 3404 9 - - JJ cord-005646-xhx9pzhj 3404 10 operative operative JJ cord-005646-xhx9pzhj 3404 11 admission admission NN cord-005646-xhx9pzhj 3404 12 to to IN cord-005646-xhx9pzhj 3404 13 planned plan VBN cord-005646-xhx9pzhj 3404 14 extubation extubation NN cord-005646-xhx9pzhj 3404 15 . . . cord-005646-xhx9pzhj 3405 1 Length length NN cord-005646-xhx9pzhj 3405 2 of of IN cord-005646-xhx9pzhj 3405 3 stay stay NN cord-005646-xhx9pzhj 3405 4 ( ( -LRB- cord-005646-xhx9pzhj 3405 5 LOS LOS NNP cord-005646-xhx9pzhj 3405 6 ) ) -RRB- cord-005646-xhx9pzhj 3405 7 was be VBD cord-005646-xhx9pzhj 3405 8 defined define VBN cord-005646-xhx9pzhj 3405 9 to to TO cord-005646-xhx9pzhj 3405 10 be be VB cord-005646-xhx9pzhj 3405 11 from from IN cord-005646-xhx9pzhj 3405 12 le le NNP cord-005646-xhx9pzhj 3405 13 from from IN cord-005646-xhx9pzhj 3405 14 the the DT cord-005646-xhx9pzhj 3405 15 ICU ICU NNP cord-005646-xhx9pzhj 3405 16 . . . cord-005646-xhx9pzhj 3405 17 _SP cord-005646-xhx9pzhj 3406 1 Cytokine cytokine NN cord-005646-xhx9pzhj 3406 2 patterns pattern NNS cord-005646-xhx9pzhj 3406 3 during during IN cord-005646-xhx9pzhj 3406 4 and and CC cord-005646-xhx9pzhj 3406 5 after after IN cord-005646-xhx9pzhj 3406 6 cardiac cardiac JJ cord-005646-xhx9pzhj 3406 7 surgery surgery NN cord-005646-xhx9pzhj 3406 8 in in IN cord-005646-xhx9pzhj 3406 9 young young JJ cord-005646-xhx9pzhj 3406 10 children child NNS cord-005646-xhx9pzhj 3406 11 . . . cord-005646-xhx9pzhj 3407 1 Especially especially RB cord-005646-xhx9pzhj 3407 2 in in IN cord-005646-xhx9pzhj 3407 3 children child NNS cord-005646-xhx9pzhj 3407 4 , , , cord-005646-xhx9pzhj 3407 5 cardiac cardiac JJ cord-005646-xhx9pzhj 3407 6 surgery surgery NN cord-005646-xhx9pzhj 3407 7 with with IN cord-005646-xhx9pzhj 3407 8 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 3407 9 bypass bypass NN cord-005646-xhx9pzhj 3407 10 ( ( -LRB- cord-005646-xhx9pzhj 3407 11 CPB CPB NNP cord-005646-xhx9pzhj 3407 12 ) ) -RRB- cord-005646-xhx9pzhj 3407 13 can can MD cord-005646-xhx9pzhj 3407 14 cause cause VB cord-005646-xhx9pzhj 3407 15 a a DT cord-005646-xhx9pzhj 3407 16 systemic systemic JJ cord-005646-xhx9pzhj 3407 17 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3407 18 response response NN cord-005646-xhx9pzhj 3407 19 . . . cord-005646-xhx9pzhj 3408 1 This this DT cord-005646-xhx9pzhj 3408 2 process process NN cord-005646-xhx9pzhj 3408 3 is be VBZ cord-005646-xhx9pzhj 3408 4 thought think VBN cord-005646-xhx9pzhj 3408 5 to to TO cord-005646-xhx9pzhj 3408 6 be be VB cord-005646-xhx9pzhj 3408 7 mainly mainly RB cord-005646-xhx9pzhj 3408 8 a a DT cord-005646-xhx9pzhj 3408 9 result result NN cord-005646-xhx9pzhj 3408 10 of of IN cord-005646-xhx9pzhj 3408 11 inflammation inflammation NN cord-005646-xhx9pzhj 3408 12 induced induce VBN cord-005646-xhx9pzhj 3408 13 by by IN cord-005646-xhx9pzhj 3408 14 surgery surgery NN cord-005646-xhx9pzhj 3408 15 and and CC cord-005646-xhx9pzhj 3408 16 exposure exposure NN cord-005646-xhx9pzhj 3408 17 of of IN cord-005646-xhx9pzhj 3408 18 blood blood NN cord-005646-xhx9pzhj 3408 19 to to IN cord-005646-xhx9pzhj 3408 20 an an DT cord-005646-xhx9pzhj 3408 21 artificial artificial JJ cord-005646-xhx9pzhj 3408 22 surface surface NN cord-005646-xhx9pzhj 3408 23 , , , cord-005646-xhx9pzhj 3408 24 and and CC cord-005646-xhx9pzhj 3408 25 of of IN cord-005646-xhx9pzhj 3408 26 reperfusion reperfusion NN cord-005646-xhx9pzhj 3408 27 injury injury NN cord-005646-xhx9pzhj 3408 28 during during IN cord-005646-xhx9pzhj 3408 29 weaning weaning NN cord-005646-xhx9pzhj 3408 30 of of IN cord-005646-xhx9pzhj 3408 31 bypass bypass NN cord-005646-xhx9pzhj 3408 32 . . . cord-005646-xhx9pzhj 3409 1 Complement complement JJ cord-005646-xhx9pzhj 3409 2 activation activation NN cord-005646-xhx9pzhj 3409 3 , , , cord-005646-xhx9pzhj 3409 4 degranulation degranulation NN cord-005646-xhx9pzhj 3409 5 of of IN cord-005646-xhx9pzhj 3409 6 granulocytes granulocyte NNS cord-005646-xhx9pzhj 3409 7 , , , cord-005646-xhx9pzhj 3409 8 induction induction NN cord-005646-xhx9pzhj 3409 9 of of IN cord-005646-xhx9pzhj 3409 10 free free JJ cord-005646-xhx9pzhj 3409 11 oxygen oxygen NN cord-005646-xhx9pzhj 3409 12 radicals radical NNS cord-005646-xhx9pzhj 3409 13 , , , cord-005646-xhx9pzhj 3409 14 endotoxemia endotoxemia NN cord-005646-xhx9pzhj 3409 15 and and CC cord-005646-xhx9pzhj 3409 16 release release NN cord-005646-xhx9pzhj 3409 17 of of IN cord-005646-xhx9pzhj 3409 18 cytokines cytokine NNS cord-005646-xhx9pzhj 3409 19 , , , cord-005646-xhx9pzhj 3409 20 are be VBP cord-005646-xhx9pzhj 3409 21 important important JJ cord-005646-xhx9pzhj 3409 22 contributing contribute VBG cord-005646-xhx9pzhj 3409 23 factors factor NNS cord-005646-xhx9pzhj 3409 24 . . . cord-005646-xhx9pzhj 3410 1 We -PRON- PRP cord-005646-xhx9pzhj 3410 2 studied study VBD cord-005646-xhx9pzhj 3410 3 cytokine cytokine JJ cord-005646-xhx9pzhj 3410 4 patterns pattern NNS cord-005646-xhx9pzhj 3410 5 before before RB cord-005646-xhx9pzhj 3410 6 , , , cord-005646-xhx9pzhj 3410 7 during during IN cord-005646-xhx9pzhj 3410 8 and and CC cord-005646-xhx9pzhj 3410 9 after after IN cord-005646-xhx9pzhj 3410 10 CPB CPB NNP cord-005646-xhx9pzhj 3410 11 in in IN cord-005646-xhx9pzhj 3410 12 young young JJ cord-005646-xhx9pzhj 3410 13 children child NNS cord-005646-xhx9pzhj 3410 14 admitted admit VBN cord-005646-xhx9pzhj 3410 15 for for IN cord-005646-xhx9pzhj 3410 16 complex complex JJ cord-005646-xhx9pzhj 3410 17 surgery surgery NN cord-005646-xhx9pzhj 3410 18 or or CC cord-005646-xhx9pzhj 3410 19 for for IN cord-005646-xhx9pzhj 3410 20 septal septal JJ cord-005646-xhx9pzhj 3410 21 defect defect NN cord-005646-xhx9pzhj 3410 22 correction correction NN cord-005646-xhx9pzhj 3410 23 . . . cord-005646-xhx9pzhj 3411 1 In in IN cord-005646-xhx9pzhj 3411 2 the the DT cord-005646-xhx9pzhj 3411 3 first first JJ cord-005646-xhx9pzhj 3411 4 group group NN cord-005646-xhx9pzhj 3411 5 , , , cord-005646-xhx9pzhj 3411 6 significant significant JJ cord-005646-xhx9pzhj 3411 7 amounts amount NNS cord-005646-xhx9pzhj 3411 8 of of IN cord-005646-xhx9pzhj 3411 9 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3411 10 and and CC cord-005646-xhx9pzhj 3411 11 IL IL NNP cord-005646-xhx9pzhj 3411 12 - - HYPH cord-005646-xhx9pzhj 3411 13 lra lra NNP cord-005646-xhx9pzhj 3411 14 could could MD cord-005646-xhx9pzhj 3411 15 be be VB cord-005646-xhx9pzhj 3411 16 detected detect VBN cord-005646-xhx9pzhj 3411 17 preoperatively preoperatively RB cord-005646-xhx9pzhj 3411 18 . . . cord-005646-xhx9pzhj 3412 1 These these DT cord-005646-xhx9pzhj 3412 2 findings finding NNS cord-005646-xhx9pzhj 3412 3 could could MD cord-005646-xhx9pzhj 3412 4 reflect reflect VB cord-005646-xhx9pzhj 3412 5 the the DT cord-005646-xhx9pzhj 3412 6 already already RB cord-005646-xhx9pzhj 3412 7 existing exist VBG cord-005646-xhx9pzhj 3412 8 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 3412 9 dysregutation dysregutation NN cord-005646-xhx9pzhj 3412 10 . . . cord-005646-xhx9pzhj 3413 1 In in IN cord-005646-xhx9pzhj 3413 2 both both DT cord-005646-xhx9pzhj 3413 3 groups group NNS cord-005646-xhx9pzhj 3413 4 , , , cord-005646-xhx9pzhj 3413 5 CPB CPB NNP cord-005646-xhx9pzhj 3413 6 procedure procedure NN cord-005646-xhx9pzhj 3413 7 upregulated upregulate VBD cord-005646-xhx9pzhj 3413 8 the the DT cord-005646-xhx9pzhj 3413 9 circulating circulate VBG cord-005646-xhx9pzhj 3413 10 pro pro JJ cord-005646-xhx9pzhj 3413 11 - - JJ cord-005646-xhx9pzhj 3413 12 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3413 13 cytokines cytokine NNS cord-005646-xhx9pzhj 3413 14 IL-6/8 IL-6/8 NNP cord-005646-xhx9pzhj 3413 15 , , , cord-005646-xhx9pzhj 3413 16 but but CC cord-005646-xhx9pzhj 3413 17 not not RB cord-005646-xhx9pzhj 3413 18 IL-1B. IL-1B. . cord-005646-xhx9pzhj 3414 1 At at IN cord-005646-xhx9pzhj 3414 2 the the DT cord-005646-xhx9pzhj 3414 3 same same JJ cord-005646-xhx9pzhj 3414 4 time time NN cord-005646-xhx9pzhj 3414 5 , , , cord-005646-xhx9pzhj 3414 6 IL IL NNP cord-005646-xhx9pzhj 3414 7 - - HYPH cord-005646-xhx9pzhj 3414 8 lra lra NNP cord-005646-xhx9pzhj 3414 9 became become VBD cord-005646-xhx9pzhj 3414 10 detectable detectable JJ cord-005646-xhx9pzhj 3414 11 . . . cord-005646-xhx9pzhj 3415 1 Therefore therefore RB cord-005646-xhx9pzhj 3415 2 , , , cord-005646-xhx9pzhj 3415 3 we -PRON- PRP cord-005646-xhx9pzhj 3415 4 suggest suggest VBP cord-005646-xhx9pzhj 3415 5 that that IN cord-005646-xhx9pzhj 3415 6 in in IN cord-005646-xhx9pzhj 3415 7 these these DT cord-005646-xhx9pzhj 3415 8 patients patient NNS cord-005646-xhx9pzhj 3415 9 the the DT cord-005646-xhx9pzhj 3415 10 production production NN cord-005646-xhx9pzhj 3415 11 of of IN cord-005646-xhx9pzhj 3415 12 the the DT cord-005646-xhx9pzhj 3415 13 anti anti JJ cord-005646-xhx9pzhj 3415 14 - - JJ cord-005646-xhx9pzhj 3415 15 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3415 16 cytokine cytokine NN cord-005646-xhx9pzhj 3415 17 IL IL NNP cord-005646-xhx9pzhj 3415 18 - - HYPH cord-005646-xhx9pzhj 3415 19 ira ira NNP cord-005646-xhx9pzhj 3415 20 was be VBD cord-005646-xhx9pzhj 3415 21 not not RB cord-005646-xhx9pzhj 3415 22 induced induce VBN cord-005646-xhx9pzhj 3415 23 by by IN cord-005646-xhx9pzhj 3415 24 the the DT cord-005646-xhx9pzhj 3415 25 preceding precede VBG cord-005646-xhx9pzhj 3415 26 acnvity acnvity NN cord-005646-xhx9pzhj 3415 27 ot ot IN cord-005646-xhx9pzhj 3415 28 pro pro JJ cord-005646-xhx9pzhj 3415 29 - - JJ cord-005646-xhx9pzhj 3415 30 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3415 31 cytoidnes cytoidne NNS cord-005646-xhx9pzhj 3415 32 . . . cord-005646-xhx9pzhj 3416 1 During during IN cord-005646-xhx9pzhj 3416 2 CPB CPB NNP cord-005646-xhx9pzhj 3416 3 , , , cord-005646-xhx9pzhj 3416 4 we -PRON- PRP cord-005646-xhx9pzhj 3416 5 noticed notice VBD cord-005646-xhx9pzhj 3416 6 a a DT cord-005646-xhx9pzhj 3416 7 sharp sharp JJ cord-005646-xhx9pzhj 3416 8 decline decline NN cord-005646-xhx9pzhj 3416 9 in in IN cord-005646-xhx9pzhj 3416 10 the the DT cord-005646-xhx9pzhj 3416 11 capacity capacity NN cord-005646-xhx9pzhj 3416 12 of of IN cord-005646-xhx9pzhj 3416 13 the the DT cord-005646-xhx9pzhj 3416 14 leucocytes leucocyte NNS cord-005646-xhx9pzhj 3416 15 to to TO cord-005646-xhx9pzhj 3416 16 secrete secrete VB cord-005646-xhx9pzhj 3416 17 IL-6/8 IL-6/8 NNP cord-005646-xhx9pzhj 3416 18 . . . cord-005646-xhx9pzhj 3417 1 The the DT cord-005646-xhx9pzhj 3417 2 ex ex JJ cord-005646-xhx9pzhj 3417 3 - - JJ cord-005646-xhx9pzhj 3417 4 vivo vivo JJ cord-005646-xhx9pzhj 3417 5 production production NN cord-005646-xhx9pzhj 3417 6 of of IN cord-005646-xhx9pzhj 3417 7 IL IL NNP cord-005646-xhx9pzhj 3417 8 - - HYPH cord-005646-xhx9pzhj 3417 9 lra lra NNP cord-005646-xhx9pzhj 3417 10 however however RB cord-005646-xhx9pzhj 3417 11 , , , cord-005646-xhx9pzhj 3417 12 was be VBD cord-005646-xhx9pzhj 3417 13 only only RB cord-005646-xhx9pzhj 3417 14 slightly slightly RB cord-005646-xhx9pzhj 3417 15 attenuated attenuated JJ cord-005646-xhx9pzhj 3417 16 . . . cord-005646-xhx9pzhj 3418 1 We -PRON- PRP cord-005646-xhx9pzhj 3418 2 conclude conclude VBP cord-005646-xhx9pzhj 3418 3 that that IN cord-005646-xhx9pzhj 3418 4 there there EX cord-005646-xhx9pzhj 3418 5 is be VBZ cord-005646-xhx9pzhj 3418 6 a a DT cord-005646-xhx9pzhj 3418 7 differential differential JJ cord-005646-xhx9pzhj 3418 8 regulatory regulatory JJ cord-005646-xhx9pzhj 3418 9 pathway pathway NN cord-005646-xhx9pzhj 3418 10 for for IN cord-005646-xhx9pzhj 3418 11 the the DT cord-005646-xhx9pzhj 3418 12 induction induction NN cord-005646-xhx9pzhj 3418 13 of of IN cord-005646-xhx9pzhj 3418 14 IL-6/8 IL-6/8 NNP cord-005646-xhx9pzhj 3418 15 and and CC cord-005646-xhx9pzhj 3418 16 IL IL NNP cord-005646-xhx9pzhj 3418 17 - - HYPH cord-005646-xhx9pzhj 3418 18 lra lra NNP cord-005646-xhx9pzhj 3418 19 . . . cord-005646-xhx9pzhj 3419 1 In in IN cord-005646-xhx9pzhj 3419 2 addition addition NN cord-005646-xhx9pzhj 3419 3 , , , cord-005646-xhx9pzhj 3419 4 we -PRON- PRP cord-005646-xhx9pzhj 3419 5 studied study VBD cord-005646-xhx9pzhj 3419 6 the the DT cord-005646-xhx9pzhj 3419 7 influence influence NN cord-005646-xhx9pzhj 3419 8 of of IN cord-005646-xhx9pzhj 3419 9 dexamethasone dexamethasone NNP cord-005646-xhx9pzhj 3419 10 administration administration NN cord-005646-xhx9pzhj 3419 11 on on IN cord-005646-xhx9pzhj 3419 12 the the DT cord-005646-xhx9pzhj 3419 13 cytokine cytokine NN cord-005646-xhx9pzhj 3419 14 pattern pattern NN cord-005646-xhx9pzhj 3419 15 . . . cord-005646-xhx9pzhj 3420 1 Administration administration NN cord-005646-xhx9pzhj 3420 2 delayed delay VBD cord-005646-xhx9pzhj 3420 3 the the DT cord-005646-xhx9pzhj 3420 4 appearance appearance NN cord-005646-xhx9pzhj 3420 5 of of IN cord-005646-xhx9pzhj 3420 6 IL-6/8 IL-6/8 NNP cord-005646-xhx9pzhj 3420 7 and and CC cord-005646-xhx9pzhj 3420 8 IL IL NNP cord-005646-xhx9pzhj 3420 9 - - HYPH cord-005646-xhx9pzhj 3420 10 Ira Ira NNP cord-005646-xhx9pzhj 3420 11 in in IN cord-005646-xhx9pzhj 3420 12 the the DT cord-005646-xhx9pzhj 3420 13 plasma plasma NN cord-005646-xhx9pzhj 3420 14 , , , cord-005646-xhx9pzhj 3420 15 Interestingly interestingly RB cord-005646-xhx9pzhj 3420 16 , , , cord-005646-xhx9pzhj 3420 17 it -PRON- PRP cord-005646-xhx9pzhj 3420 18 did do VBD cord-005646-xhx9pzhj 3420 19 only only RB cord-005646-xhx9pzhj 3420 20 interfere interfere VB cord-005646-xhx9pzhj 3420 21 with with IN cord-005646-xhx9pzhj 3420 22 the the DT cord-005646-xhx9pzhj 3420 23 ex ex JJ cord-005646-xhx9pzhj 3420 24 - - JJ cord-005646-xhx9pzhj 3420 25 vivo vivo JJ cord-005646-xhx9pzhj 3420 26 production production NN cord-005646-xhx9pzhj 3420 27 of of IN cord-005646-xhx9pzhj 3420 28 pro pro JJ cord-005646-xhx9pzhj 3420 29 - - JJ cord-005646-xhx9pzhj 3420 30 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3420 31 cytokines cytokine NNS cord-005646-xhx9pzhj 3420 32 . . . cord-005646-xhx9pzhj 3421 1 The the DT cord-005646-xhx9pzhj 3421 2 latter latter JJ cord-005646-xhx9pzhj 3421 3 supports support VBZ cord-005646-xhx9pzhj 3421 4 our -PRON- PRP$ cord-005646-xhx9pzhj 3421 5 hypothesis hypothesis NN cord-005646-xhx9pzhj 3421 6 that that IN cord-005646-xhx9pzhj 3421 7 production production NN cord-005646-xhx9pzhj 3421 8 of of IN cord-005646-xhx9pzhj 3421 9 IL-6/8 IL-6/8 NNP cord-005646-xhx9pzhj 3421 10 and and CC cord-005646-xhx9pzhj 3421 11 of of IN cord-005646-xhx9pzhj 3421 12 IL IL NNP cord-005646-xhx9pzhj 3421 13 - - HYPH cord-005646-xhx9pzhj 3421 14 lra lra NNP cord-005646-xhx9pzhj 3421 15 is be VBZ cord-005646-xhx9pzhj 3421 16 regulated regulate VBN cord-005646-xhx9pzhj 3421 17 by by IN cord-005646-xhx9pzhj 3421 18 two two CD cord-005646-xhx9pzhj 3421 19 independent independent JJ cord-005646-xhx9pzhj 3421 20 pathways pathway NNS cord-005646-xhx9pzhj 3421 21 , , , cord-005646-xhx9pzhj 3421 22 ( ( -LRB- cord-005646-xhx9pzhj 3421 23 60 60 CD cord-005646-xhx9pzhj 3421 24 % % NN cord-005646-xhx9pzhj 3421 25 ) ) -RRB- cord-005646-xhx9pzhj 3421 26 of of IN cord-005646-xhx9pzhj 3421 27 43 43 CD cord-005646-xhx9pzhj 3421 28 pts pt NNS cord-005646-xhx9pzhj 3421 29 . . . cord-005646-xhx9pzhj 3422 1 82 82 CD cord-005646-xhx9pzhj 3422 2 % % NN cord-005646-xhx9pzhj 3422 3 ofpts ofpts NN cord-005646-xhx9pzhj 3423 1 < < NNP cord-005646-xhx9pzhj 3423 2 12 12 CD cord-005646-xhx9pzhj 3423 3 months month NNS cord-005646-xhx9pzhj 3423 4 of of IN cord-005646-xhx9pzhj 3423 5 age age NN cord-005646-xhx9pzhj 3423 6 developed develop VBD cord-005646-xhx9pzhj 3423 7 metabolic metabolic JJ cord-005646-xhx9pzhj 3423 8 alkalosis alkalosis NN cord-005646-xhx9pzhj 3423 9 as as IN cord-005646-xhx9pzhj 3423 10 compared compare VBN cord-005646-xhx9pzhj 3423 11 with with IN cord-005646-xhx9pzhj 3423 12 38 38 CD cord-005646-xhx9pzhj 3423 13 % % NN cord-005646-xhx9pzhj 3423 14 ofpts ofpt NNS cord-005646-xhx9pzhj 3423 15 > > XX cord-005646-xhx9pzhj 3423 16 12 12 CD cord-005646-xhx9pzhj 3423 17 months month NNS cord-005646-xhx9pzhj 3423 18 of of IN cord-005646-xhx9pzhj 3423 19 age age NN cord-005646-xhx9pzhj 3423 20 . . . cord-005646-xhx9pzhj 3424 1 The the DT cord-005646-xhx9pzhj 3424 2 infants infant NNS cord-005646-xhx9pzhj 3424 3 with with IN cord-005646-xhx9pzhj 3424 4 metabolic metabolic JJ cord-005646-xhx9pzhj 3424 5 alkalosis alkalosis NN cord-005646-xhx9pzhj 3424 6 received receive VBD cord-005646-xhx9pzhj 3424 7 more more RBR cord-005646-xhx9pzhj 3424 8 citrated citrate VBN cord-005646-xhx9pzhj 3424 9 blood blood NN cord-005646-xhx9pzhj 3424 10 products product NNS cord-005646-xhx9pzhj 3424 11 and and CC cord-005646-xhx9pzhj 3424 12 furosemide furosemide NN cord-005646-xhx9pzhj 3424 13 . . . cord-005646-xhx9pzhj 3425 1 Following follow VBG cord-005646-xhx9pzhj 3425 2 cardiac cardiac JJ cord-005646-xhx9pzhj 3425 3 pulmonary pulmonary NN cord-005646-xhx9pzhj 3425 4 bypass bypass NN cord-005646-xhx9pzhj 3425 5 the the DT cord-005646-xhx9pzhj 3425 6 highest high JJS cord-005646-xhx9pzhj 3425 7 pH ph NN cord-005646-xhx9pzhj 3425 8 - - HYPH cord-005646-xhx9pzhj 3425 9 values value NNS cord-005646-xhx9pzhj 3425 10 and and CC cord-005646-xhx9pzhj 3425 11 BE be NN cord-005646-xhx9pzhj 3425 12 - - HYPH cord-005646-xhx9pzhj 3425 13 values value NNS cord-005646-xhx9pzhj 3426 1 were be VBD cord-005646-xhx9pzhj 3426 2 observed observe VBN cord-005646-xhx9pzhj 3426 3 24 24 CD cord-005646-xhx9pzhj 3426 4 - - SYM cord-005646-xhx9pzhj 3426 5 48 48 CD cord-005646-xhx9pzhj 3426 6 hours hour NNS cord-005646-xhx9pzhj 3426 7 and and CC cord-005646-xhx9pzhj 3426 8 48 48 CD cord-005646-xhx9pzhj 3426 9 - - SYM cord-005646-xhx9pzhj 3426 10 72 72 CD cord-005646-xhx9pzhj 3426 11 hours hour NNS cord-005646-xhx9pzhj 3426 12 , , , cord-005646-xhx9pzhj 3426 13 respectively respectively RB cord-005646-xhx9pzhj 3426 14 . . . cord-005646-xhx9pzhj 3427 1 II II NNP cord-005646-xhx9pzhj 3427 2 . . . cord-005646-xhx9pzhj 3428 1 prospective prospective JJ cord-005646-xhx9pzhj 3428 2 study study NN cord-005646-xhx9pzhj 3428 3 : : : cord-005646-xhx9pzhj 3428 4 Metabolic metabolic JJ cord-005646-xhx9pzhj 3428 5 alkalosis alkalosis NN cord-005646-xhx9pzhj 3428 6 was be VBD cord-005646-xhx9pzhj 3428 7 registerd registerd VBN cord-005646-xhx9pzhj 3428 8 in in IN cord-005646-xhx9pzhj 3428 9 2 2 CD cord-005646-xhx9pzhj 3428 10 t t NN cord-005646-xhx9pzhj 3428 11 children child NNS cord-005646-xhx9pzhj 3428 12 ( ( -LRB- cord-005646-xhx9pzhj 3428 13 70 70 CD cord-005646-xhx9pzhj 3428 14 % % NN cord-005646-xhx9pzhj 3428 15 ) ) -RRB- cord-005646-xhx9pzhj 3428 16 , , , cord-005646-xhx9pzhj 3428 17 8 8 CD cord-005646-xhx9pzhj 3428 18 of of IN cord-005646-xhx9pzhj 3428 19 those those DT cord-005646-xhx9pzhj 3428 20 < < XX cord-005646-xhx9pzhj 3428 21 12 12 CD cord-005646-xhx9pzhj 3428 22 month month NN cord-005646-xhx9pzhj 3428 23 ( ( -LRB- cord-005646-xhx9pzhj 3428 24 75 75 CD cord-005646-xhx9pzhj 3428 25 % % NN cord-005646-xhx9pzhj 3428 26 ) ) -RRB- cord-005646-xhx9pzhj 3428 27 developed develop VBN cord-005646-xhx9pzhj 3428 28 metabolic metabolic JJ cord-005646-xhx9pzhj 3428 29 alkalosis alkalosis NN cord-005646-xhx9pzhj 3428 30 and and CC cord-005646-xhx9pzhj 3428 31 67 67 CD cord-005646-xhx9pzhj 3428 32 % % NN cord-005646-xhx9pzhj 3428 33 of of IN cord-005646-xhx9pzhj 3428 34 those those DT cord-005646-xhx9pzhj 3428 35 elder eld JJR cord-005646-xhx9pzhj 3428 36 than than IN cord-005646-xhx9pzhj 3428 37 12 12 CD cord-005646-xhx9pzhj 3428 38 monms monms NNP cord-005646-xhx9pzhj 3428 39 . . . cord-005646-xhx9pzhj 3429 1 Durmg Durmg NNP cord-005646-xhx9pzhj 3429 2 the the DT cord-005646-xhx9pzhj 3429 3 postoperative postoperative JJ cord-005646-xhx9pzhj 3429 4 course course NN cord-005646-xhx9pzhj 3429 5 patients patient NNS cord-005646-xhx9pzhj 3429 6 younger young JJR cord-005646-xhx9pzhj 3429 7 than than IN cord-005646-xhx9pzhj 3429 8 12 12 CD cord-005646-xhx9pzhj 3429 9 months month NNS cord-005646-xhx9pzhj 3429 10 developed develop VBD cord-005646-xhx9pzhj 3429 11 the the DT cord-005646-xhx9pzhj 3429 12 highest high JJS cord-005646-xhx9pzhj 3429 13 pH ph NN cord-005646-xhx9pzhj 3429 14 - - : cord-005646-xhx9pzhj 3429 15 and and CC cord-005646-xhx9pzhj 3429 16 base base VB cord-005646-xhx9pzhj 3429 17 excess excess JJ cord-005646-xhx9pzhj 3429 18 values value NNS cord-005646-xhx9pzhj 3429 19 after after IN cord-005646-xhx9pzhj 3429 20 102 102 CD cord-005646-xhx9pzhj 3429 21 and and CC cord-005646-xhx9pzhj 3429 22 t05 t05 CD cord-005646-xhx9pzhj 3429 23 hours hour NNS cord-005646-xhx9pzhj 3429 24 , , , cord-005646-xhx9pzhj 3429 25 in in IN cord-005646-xhx9pzhj 3429 26 the the DT cord-005646-xhx9pzhj 3429 27 subset subset NN cord-005646-xhx9pzhj 3429 28 of of IN cord-005646-xhx9pzhj 3429 29 the the DT cord-005646-xhx9pzhj 3429 30 older old JJR cord-005646-xhx9pzhj 3429 31 patients patient NNS cord-005646-xhx9pzhj 3429 32 maximum maximum JJ cord-005646-xhx9pzhj 3430 1 pH pH NNP cord-005646-xhx9pzhj 3430 2 and and CC cord-005646-xhx9pzhj 3430 3 base base NN cord-005646-xhx9pzhj 3430 4 excess excess NN cord-005646-xhx9pzhj 3430 5 was be VBD cord-005646-xhx9pzhj 3430 6 found find VBN cord-005646-xhx9pzhj 3430 7 after after IN cord-005646-xhx9pzhj 3430 8 48 48 CD cord-005646-xhx9pzhj 3430 9 and and CC cord-005646-xhx9pzhj 3430 10 81 81 CD cord-005646-xhx9pzhj 3430 11 hours hour NNS cord-005646-xhx9pzhj 3430 12 , , , cord-005646-xhx9pzhj 3430 13 respectively respectively RB cord-005646-xhx9pzhj 3430 14 . . . cord-005646-xhx9pzhj 3431 1 In in IN cord-005646-xhx9pzhj 3431 2 one one CD cord-005646-xhx9pzhj 3431 3 case case NN cord-005646-xhx9pzhj 3431 4 the the DT cord-005646-xhx9pzhj 3431 5 top top JJ cord-005646-xhx9pzhj 3431 6 level level NN cord-005646-xhx9pzhj 3431 7 ofpH ofph JJ cord-005646-xhx9pzhj 3431 8 - - HYPH cord-005646-xhx9pzhj 3431 9 value value NN cord-005646-xhx9pzhj 3431 10 exceeded exceed VBD cord-005646-xhx9pzhj 3431 11 7.6 7.6 CD cord-005646-xhx9pzhj 3431 12 , , , cord-005646-xhx9pzhj 3431 13 the the DT cord-005646-xhx9pzhj 3431 14 base base NN cord-005646-xhx9pzhj 3431 15 excess excess NN cord-005646-xhx9pzhj 3431 16 +20 +20 CD cord-005646-xhx9pzhj 3431 17 mvalB. mvalb. NN cord-005646-xhx9pzhj 3431 18 Conclusion conclusion NN cord-005646-xhx9pzhj 3431 19 : : : cord-005646-xhx9pzhj 3431 20 Children child NNS cord-005646-xhx9pzhj 3431 21 undergoing undergo VBG cord-005646-xhx9pzhj 3431 22 cardiac cardiac JJ cord-005646-xhx9pzhj 3431 23 surgery surgery NN cord-005646-xhx9pzhj 3431 24 with with IN cord-005646-xhx9pzhj 3431 25 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 3431 26 bypass bypass NN cord-005646-xhx9pzhj 3431 27 often often RB cord-005646-xhx9pzhj 3431 28 develop develop VBP cord-005646-xhx9pzhj 3431 29 metabolic metabolic JJ cord-005646-xhx9pzhj 3431 30 alkalosis alkalosis NN cord-005646-xhx9pzhj 3431 31 . . . cord-005646-xhx9pzhj 3432 1 In in IN cord-005646-xhx9pzhj 3432 2 contrast contrast NN cord-005646-xhx9pzhj 3432 3 to to IN cord-005646-xhx9pzhj 3432 4 previous previous JJ cord-005646-xhx9pzhj 3432 5 reports report NNS cord-005646-xhx9pzhj 3432 6 , , , cord-005646-xhx9pzhj 3432 7 we -PRON- PRP cord-005646-xhx9pzhj 3432 8 did do VBD cord-005646-xhx9pzhj 3432 9 not not RB cord-005646-xhx9pzhj 3432 10 observe observe VB cord-005646-xhx9pzhj 3432 11 an an DT cord-005646-xhx9pzhj 3432 12 association association NN cord-005646-xhx9pzhj 3432 13 between between IN cord-005646-xhx9pzhj 3432 14 metabolic metabolic JJ cord-005646-xhx9pzhj 3432 15 alkalosis alkalosis NN cord-005646-xhx9pzhj 3432 16 and and CC cord-005646-xhx9pzhj 3432 17 mortality mortality NN cord-005646-xhx9pzhj 3432 18 , , , cord-005646-xhx9pzhj 3432 19 nor nor CC cord-005646-xhx9pzhj 3432 20 greater great JJR cord-005646-xhx9pzhj 3432 21 frequency frequency NN cord-005646-xhx9pzhj 3432 22 of of IN cord-005646-xhx9pzhj 3432 23 cardiac cardiac JJ cord-005646-xhx9pzhj 3432 24 arrythmias arrythmia NNS cord-005646-xhx9pzhj 3432 25 or or CC cord-005646-xhx9pzhj 3432 26 prolonged prolong VBN cord-005646-xhx9pzhj 3432 27 mechanical mechanical JJ cord-005646-xhx9pzhj 3432 28 ventilation ventilation NN cord-005646-xhx9pzhj 3432 29 . . . cord-005646-xhx9pzhj 3433 1 In in IN cord-005646-xhx9pzhj 3433 2 context context NN cord-005646-xhx9pzhj 3433 3 with with IN cord-005646-xhx9pzhj 3433 4 decreasing decrease VBG cord-005646-xhx9pzhj 3433 5 serum serum NN cord-005646-xhx9pzhj 3433 6 lactate lactate NN cord-005646-xhx9pzhj 3433 7 levels level NNS cord-005646-xhx9pzhj 3433 8 , , , cord-005646-xhx9pzhj 3433 9 our -PRON- PRP$ cord-005646-xhx9pzhj 3433 10 data datum NNS cord-005646-xhx9pzhj 3433 11 show show VBP cord-005646-xhx9pzhj 3433 12 positive positive JJ cord-005646-xhx9pzhj 3433 13 correlation correlation NN cord-005646-xhx9pzhj 3433 14 of of IN cord-005646-xhx9pzhj 3433 15 metabolic metabolic JJ cord-005646-xhx9pzhj 3433 16 alkalosis alkalosis NN cord-005646-xhx9pzhj 3433 17 with with IN cord-005646-xhx9pzhj 3433 18 postoperative postoperative JJ cord-005646-xhx9pzhj 3433 19 improvement improvement NN cord-005646-xhx9pzhj 3433 20 of of IN cord-005646-xhx9pzhj 3433 21 liver liver NN cord-005646-xhx9pzhj 3433 22 function function NN cord-005646-xhx9pzhj 3433 23 . . . cord-005646-xhx9pzhj 3434 1 Respirator respirator NN cord-005646-xhx9pzhj 3434 2 , , , cord-005646-xhx9pzhj 3434 3 mechanics mechanic NNS cord-005646-xhx9pzhj 3434 4 and and CC cord-005646-xhx9pzhj 3434 5 weaning weaning NN cord-005646-xhx9pzhj 3434 6 outcome outcome NN cord-005646-xhx9pzhj 3434 7 in in IN cord-005646-xhx9pzhj 3434 8 children child NNS cord-005646-xhx9pzhj 3434 9 undergoing undergo VBG cord-005646-xhx9pzhj 3434 10 cardipvascular cardipvascular JJ cord-005646-xhx9pzhj 3434 11 surgery surgery NN cord-005646-xhx9pzhj 3434 12 . . . cord-005646-xhx9pzhj 3435 1 Vassallo Vassallo NNP cord-005646-xhx9pzhj 3435 2 J. J. NNP cord-005646-xhx9pzhj 3435 3 , , , cord-005646-xhx9pzhj 3435 4 Cernadas Cernadas NNP cord-005646-xhx9pzhj 3435 5 C. C. NNP cord-005646-xhx9pzhj 3435 6 , , , cord-005646-xhx9pzhj 3435 7 Saporiti Saporiti NNP cord-005646-xhx9pzhj 3435 8 A. A. NNP cord-005646-xhx9pzhj 3435 9 , , , cord-005646-xhx9pzhj 3435 10 Landry Landry NNP cord-005646-xhx9pzhj 3435 11 L. L. NNP cord-005646-xhx9pzhj 3435 12 , , , cord-005646-xhx9pzhj 3435 13 Rivello Rivello NNP cord-005646-xhx9pzhj 3435 14 G. G. NNP cord-005646-xhx9pzhj 3435 15 , , , cord-005646-xhx9pzhj 3435 16 Buamsha Buamsha NNP cord-005646-xhx9pzhj 3435 17 D. D. NNP cord-005646-xhx9pzhj 3435 18 , , , cord-005646-xhx9pzhj 3435 19 Rufach Rufach NNP cord-005646-xhx9pzhj 3435 20 D. D. NNP cord-005646-xhx9pzhj 3435 21 , , , cord-005646-xhx9pzhj 3435 22 Magliola Magliola NNP cord-005646-xhx9pzhj 3435 23 R. R. NNP cord-005646-xhx9pzhj 3435 24 Mechanical Mechanical NNP cord-005646-xhx9pzhj 3435 25 ventilation ventilation NN cord-005646-xhx9pzhj 3435 26 ( ( -LRB- cord-005646-xhx9pzhj 3435 27 MV MV NNP cord-005646-xhx9pzhj 3435 28 ) ) -RRB- cord-005646-xhx9pzhj 3435 29 and and CC cord-005646-xhx9pzhj 3435 30 acute acute JJ cord-005646-xhx9pzhj 3435 31 respiratory respiratory JJ cord-005646-xhx9pzhj 3435 32 failure failure NN cord-005646-xhx9pzhj 3435 33 are be VBP cord-005646-xhx9pzhj 3435 34 common common JJ cord-005646-xhx9pzhj 3435 35 events event NNS cord-005646-xhx9pzhj 3435 36 in in IN cord-005646-xhx9pzhj 3435 37 children child NNS cord-005646-xhx9pzhj 3435 38 unergolg unergolg VBP cord-005646-xhx9pzhj 3435 39 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 3435 40 surgery surgery NN cord-005646-xhx9pzhj 3435 41 ( ( -LRB- cord-005646-xhx9pzhj 3435 42 CVS CVS NNP cord-005646-xhx9pzhj 3435 43 ) ) -RRB- cord-005646-xhx9pzhj 3435 44 , , , cord-005646-xhx9pzhj 3435 45 The the DT cord-005646-xhx9pzhj 3435 46 development development NN cord-005646-xhx9pzhj 3435 47 of of IN cord-005646-xhx9pzhj 3435 48 new new JJ cord-005646-xhx9pzhj 3435 49 techniques technique NNS cord-005646-xhx9pzhj 3435 50 helped help VBD cord-005646-xhx9pzhj 3435 51 to to TO cord-005646-xhx9pzhj 3435 52 measure measure VB cord-005646-xhx9pzhj 3435 53 some some DT cord-005646-xhx9pzhj 3435 54 of of IN cord-005646-xhx9pzhj 3435 55 the the DT cord-005646-xhx9pzhj 3435 56 main main JJ cord-005646-xhx9pzhj 3435 57 respiratory respiratory JJ cord-005646-xhx9pzhj 3435 58 mechanics mechanic NNS cord-005646-xhx9pzhj 3435 59 ( ( -LRB- cord-005646-xhx9pzhj 3435 60 RM RM NNP cord-005646-xhx9pzhj 3435 61 ) ) -RRB- cord-005646-xhx9pzhj 3435 62 in in IN cord-005646-xhx9pzhj 3435 63 a a DT cord-005646-xhx9pzhj 3435 64 non non JJ cord-005646-xhx9pzhj 3435 65 invasive invasive JJ cord-005646-xhx9pzhj 3435 66 fashion fashion NN cord-005646-xhx9pzhj 3435 67 . . . cord-005646-xhx9pzhj 3436 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 3436 2 goal goal NN cord-005646-xhx9pzhj 3436 3 was be VBD cord-005646-xhx9pzhj 3436 4 to to TO cord-005646-xhx9pzhj 3436 5 evaluate evaluate VB cord-005646-xhx9pzhj 3436 6 the the DT cord-005646-xhx9pzhj 3436 7 predictive predictive JJ cord-005646-xhx9pzhj 3436 8 value value NN cord-005646-xhx9pzhj 3436 9 of of IN cord-005646-xhx9pzhj 3436 10 these these DT cord-005646-xhx9pzhj 3436 11 measurements measurement NNS cord-005646-xhx9pzhj 3436 12 in in IN cord-005646-xhx9pzhj 3436 13 weaning weaning NN cord-005646-xhx9pzhj 3436 14 ( ( -LRB- cord-005646-xhx9pzhj 3436 15 W w NN cord-005646-xhx9pzhj 3436 16 ) ) -RRB- cord-005646-xhx9pzhj 3436 17 outcome outcome NN cord-005646-xhx9pzhj 3436 18 in in IN cord-005646-xhx9pzhj 3436 19 these these DT cord-005646-xhx9pzhj 3436 20 patients patient NNS cord-005646-xhx9pzhj 3436 21 , , , cord-005646-xhx9pzhj 3436 22 Patients patient NNS cord-005646-xhx9pzhj 3436 23 and and CC cord-005646-xhx9pzhj 3436 24 methods method NNS cord-005646-xhx9pzhj 3436 25 : : : cord-005646-xhx9pzhj 3436 26 we -PRON- PRP cord-005646-xhx9pzhj 3436 27 prospectively prospectively RB cord-005646-xhx9pzhj 3436 28 evaluated evaluate VBD cord-005646-xhx9pzhj 3436 29 children child NNS cord-005646-xhx9pzhj 3436 30 considered consider VBN cord-005646-xhx9pzhj 3436 31 clinically clinically RB cord-005646-xhx9pzhj 3436 32 to to TO cord-005646-xhx9pzhj 3436 33 be be VB cord-005646-xhx9pzhj 3436 34 ready ready JJ cord-005646-xhx9pzhj 3436 35 for for IN cord-005646-xhx9pzhj 3436 36 W W NNP cord-005646-xhx9pzhj 3436 37 with with IN cord-005646-xhx9pzhj 3436 38 < < XX cord-005646-xhx9pzhj 3436 39 20 20 CD cord-005646-xhx9pzhj 3436 40 kg kg NNS cord-005646-xhx9pzhj 3437 1 and and CC cord-005646-xhx9pzhj 3437 2 > > XX cord-005646-xhx9pzhj 3437 3 24 24 CD cord-005646-xhx9pzhj 3437 4 hs hs NNP cord-005646-xhx9pzhj 3437 5 MV MV NNP cord-005646-xhx9pzhj 3437 6 . . . cord-005646-xhx9pzhj 3438 1 Patients patient NNS cord-005646-xhx9pzhj 3438 2 with with IN cord-005646-xhx9pzhj 3438 3 diaphragm diaphragm NN cord-005646-xhx9pzhj 3438 4 paralysis paralysis NN cord-005646-xhx9pzhj 3438 5 and and CC cord-005646-xhx9pzhj 3438 6 those those DT cord-005646-xhx9pzhj 3438 7 who who WP cord-005646-xhx9pzhj 3438 8 failed fail VBD cord-005646-xhx9pzhj 3438 9 W w NN cord-005646-xhx9pzhj 3438 10 because because IN cord-005646-xhx9pzhj 3438 11 of of IN cord-005646-xhx9pzhj 3438 12 upper upper JJ cord-005646-xhx9pzhj 3438 13 airway airway NN cord-005646-xhx9pzhj 3438 14 obstruction obstruction NN cord-005646-xhx9pzhj 3438 15 were be VBD cord-005646-xhx9pzhj 3438 16 excluded exclude VBN cord-005646-xhx9pzhj 3438 17 . . . cord-005646-xhx9pzhj 3439 1 Before before IN cord-005646-xhx9pzhj 3439 2 patient patient NN cord-005646-xhx9pzhj 3439 3 extubation extubation NN cord-005646-xhx9pzhj 3439 4 the the DT cord-005646-xhx9pzhj 3439 5 following follow VBG cord-005646-xhx9pzhj 3439 6 measurements measurement NNS cord-005646-xhx9pzhj 3439 7 were be VBD cord-005646-xhx9pzhj 3439 8 recorded record VBN cord-005646-xhx9pzhj 3439 9 during during IN cord-005646-xhx9pzhj 3439 10 spontaneous spontaneous JJ cord-005646-xhx9pzhj 3439 11 ventilation ventilation NN cord-005646-xhx9pzhj 3439 12 ( ( -LRB- cord-005646-xhx9pzhj 3439 13 CPAP CPAP NNP cord-005646-xhx9pzhj 3439 14 / / SYM cord-005646-xhx9pzhj 3439 15 T T NNP cord-005646-xhx9pzhj 3439 16 piece piece NN cord-005646-xhx9pzhj 3439 17 ) ) -RRB- cord-005646-xhx9pzhj 3439 18 using use VBG cord-005646-xhx9pzhj 3439 19 the the DT cord-005646-xhx9pzhj 3439 20 CP CP NNP cord-005646-xhx9pzhj 3439 21 100 100 CD cord-005646-xhx9pzhj 3439 22 Neonatal neonatal JJ cord-005646-xhx9pzhj 3439 23 Pulmonary Pulmonary NNP cord-005646-xhx9pzhj 3439 24 Monitor Monitor NNP cord-005646-xhx9pzhj 3439 25 BICORE BICORE NNP cord-005646-xhx9pzhj 3439 26 ( ( -LRB- cord-005646-xhx9pzhj 3439 27 lrvine lrvine NNP cord-005646-xhx9pzhj 3439 28 , , , cord-005646-xhx9pzhj 3439 29 CA CA NNP cord-005646-xhx9pzhj 3439 30 ) ) -RRB- cord-005646-xhx9pzhj 3439 31 : : : cord-005646-xhx9pzhj 3439 32 total total JJ cord-005646-xhx9pzhj 3439 33 respiratory respiratory JJ cord-005646-xhx9pzhj 3439 34 system system NN cord-005646-xhx9pzhj 3439 35 static static JJ cord-005646-xhx9pzhj 3439 36 compliance compliance NN cord-005646-xhx9pzhj 3439 37 ( ( -LRB- cord-005646-xhx9pzhj 3439 38 CSSR CSSR NNP cord-005646-xhx9pzhj 3439 39 ) ) -RRB- cord-005646-xhx9pzhj 3439 40 and and CC cord-005646-xhx9pzhj 3439 41 resistance resistance NN cord-005646-xhx9pzhj 3439 42 ( ( -LRB- cord-005646-xhx9pzhj 3439 43 RTS RTS NNP cord-005646-xhx9pzhj 3439 44 ) ) -RRB- cord-005646-xhx9pzhj 3439 45 , , , cord-005646-xhx9pzhj 3439 46 rapid rapid JJ cord-005646-xhx9pzhj 3439 47 shallow shallow JJ cord-005646-xhx9pzhj 3439 48 breathing breathing NN cord-005646-xhx9pzhj 3439 49 index index NN cord-005646-xhx9pzhj 3439 50 ( ( -LRB- cord-005646-xhx9pzhj 3439 51 RSBI RSBI NNP cord-005646-xhx9pzhj 3439 52 ) ) -RRB- cord-005646-xhx9pzhj 3439 53 . . . cord-005646-xhx9pzhj 3440 1 Maximal maximal JJ cord-005646-xhx9pzhj 3440 2 inspiratory inspiratory JJ cord-005646-xhx9pzhj 3440 3 negative negative JJ cord-005646-xhx9pzhj 3440 4 pressure pressure NN cord-005646-xhx9pzhj 3440 5 ( ( -LRB- cord-005646-xhx9pzhj 3440 6 Pi Pi NNP cord-005646-xhx9pzhj 3440 7 max max NNP cord-005646-xhx9pzhj 3440 8 ) ) -RRB- cord-005646-xhx9pzhj 3440 9 was be VBD cord-005646-xhx9pzhj 3440 10 measured measure VBN cord-005646-xhx9pzhj 3440 11 using use VBG cord-005646-xhx9pzhj 3440 12 an an DT cord-005646-xhx9pzhj 3440 13 unidirectional unidirectional JJ cord-005646-xhx9pzhj 3440 14 expiratory expiratory JJ cord-005646-xhx9pzhj 3440 15 valve valve NN cord-005646-xhx9pzhj 3440 16 . . . cord-005646-xhx9pzhj 3441 1 Threshold threshold NN cord-005646-xhx9pzhj 3441 2 values value NNS cord-005646-xhx9pzhj 3441 3 predicting predict VBG cord-005646-xhx9pzhj 3441 4 W w IN cord-005646-xhx9pzhj 3441 5 success success NN cord-005646-xhx9pzhj 3441 6 ( ( -LRB- cord-005646-xhx9pzhj 3441 7 Ws Ws NNP cord-005646-xhx9pzhj 3441 8 ) ) -RRB- cord-005646-xhx9pzhj 3441 9 were be VBD cord-005646-xhx9pzhj 3441 10 : : : cord-005646-xhx9pzhj 3441 11 CSSR CSSR NNP cord-005646-xhx9pzhj 3441 12 > > XX cord-005646-xhx9pzhj 3442 1 0.5 0.5 CD cord-005646-xhx9pzhj 3442 2 ml ml NN cord-005646-xhx9pzhj 3442 3 / / SYM cord-005646-xhx9pzhj 3442 4 cm cm NNP cord-005646-xhx9pzhj 3442 5 H20 H20 NNP cord-005646-xhx9pzhj 3442 6 , , , cord-005646-xhx9pzhj 3442 7 RTS RTS NNP cord-005646-xhx9pzhj 3442 8 < < XX cord-005646-xhx9pzhj 3442 9 75 75 CD cord-005646-xhx9pzhj 3442 10 cm cm NNS cord-005646-xhx9pzhj 3442 11 H20 h20 NN cord-005646-xhx9pzhj 3442 12 /L /L , cord-005646-xhx9pzhj 3442 13 / / SYM cord-005646-xhx9pzhj 3442 14 sec sec NNP cord-005646-xhx9pzhj 3442 15 , , , cord-005646-xhx9pzhj 3442 16 RSBI RSBI NNPS cord-005646-xhx9pzhj 3442 17 160 160 CD cord-005646-xhx9pzhj 3442 18 and and CC cord-005646-xhx9pzhj 3442 19 Pi pi NN cord-005646-xhx9pzhj 3442 20 max max NN cord-005646-xhx9pzhj 3443 1 > > XX cord-005646-xhx9pzhj 3444 1 -30 -30 NNP cord-005646-xhx9pzhj 3444 2 cm cm NNP cord-005646-xhx9pzhj 3444 3 t120 t120 NNP cord-005646-xhx9pzhj 3444 4 . . . cord-005646-xhx9pzhj 3445 1 W w NN cord-005646-xhx9pzhj 3445 2 failures failure NNS cord-005646-xhx9pzhj 3445 3 ( ( -LRB- cord-005646-xhx9pzhj 3446 1 Wf Wf NNP cord-005646-xhx9pzhj 3446 2 ) ) -RRB- cord-005646-xhx9pzhj 3446 3 -patient -patient : cord-005646-xhx9pzhj 3446 4 reintubation reintubation NN cord-005646-xhx9pzhj 3446 5 within within IN cord-005646-xhx9pzhj 3446 6 the the DT cord-005646-xhx9pzhj 3446 7 following follow VBG cord-005646-xhx9pzhj 3446 8 48 48 CD cord-005646-xhx9pzhj 3446 9 hs hs NNP cord-005646-xhx9pzhj 3446 10 , , , cord-005646-xhx9pzhj 3446 11 These these DT cord-005646-xhx9pzhj 3446 12 values value NNS cord-005646-xhx9pzhj 3446 13 were be VBD cord-005646-xhx9pzhj 3446 14 compared compare VBN cord-005646-xhx9pzhj 3446 15 between between IN cord-005646-xhx9pzhj 3446 16 W w NN cord-005646-xhx9pzhj 3446 17 success success NN cord-005646-xhx9pzhj 3446 18 and and CC cord-005646-xhx9pzhj 3446 19 failures failure NNS cord-005646-xhx9pzhj 3446 20 using use VBG cord-005646-xhx9pzhj 3446 21 Fisher Fisher NNP cord-005646-xhx9pzhj 3446 22 exact exact JJ cord-005646-xhx9pzhj 3446 23 test test NN cord-005646-xhx9pzhj 3446 24 . . . cord-005646-xhx9pzhj 3447 1 An an DT cord-005646-xhx9pzhj 3447 2 apriori apriori JJ cord-005646-xhx9pzhj 3447 3 level level NN cord-005646-xhx9pzhj 3447 4 of of IN cord-005646-xhx9pzhj 3447 5 statistical statistical JJ cord-005646-xhx9pzhj 3447 6 significance significance NN cord-005646-xhx9pzhj 3447 7 was be VBD cord-005646-xhx9pzhj 3447 8 chosen choose VBN cord-005646-xhx9pzhj 3447 9 at at IN cord-005646-xhx9pzhj 3447 10 p p NN cord-005646-xhx9pzhj 3447 11 < < XX cord-005646-xhx9pzhj 3447 12 0.05 0.05 CD cord-005646-xhx9pzhj 3447 13 . . . cord-005646-xhx9pzhj 3448 1 4 4 LS cord-005646-xhx9pzhj 3448 2 considered consider VBN cord-005646-xhx9pzhj 3448 3 , , , cord-005646-xhx9pzhj 3448 4 an an DT cord-005646-xhx9pzhj 3448 5 increase increase NN cord-005646-xhx9pzhj 3448 6 in in IN cord-005646-xhx9pzhj 3448 7 TNF TNF NNP cord-005646-xhx9pzhj 3448 8 - - : cord-005646-xhx9pzhj 3448 9 a a DT cord-005646-xhx9pzhj 3448 10 levels level NNS cord-005646-xhx9pzhj 3448 11 is be VBZ cord-005646-xhx9pzhj 3448 12 observed observe VBN cord-005646-xhx9pzhj 3448 13 after after IN cord-005646-xhx9pzhj 3448 14 cardiac cardiac JJ cord-005646-xhx9pzhj 3448 15 surgery surgery NN cord-005646-xhx9pzhj 3448 16 ( ( -LRB- cord-005646-xhx9pzhj 3448 17 p<0.001 p<0.001 CD cord-005646-xhx9pzhj 3448 18 ) ) -RRB- cord-005646-xhx9pzhj 3448 19 with with IN cord-005646-xhx9pzhj 3448 20 a a DT cord-005646-xhx9pzhj 3448 21 return return NN cord-005646-xhx9pzhj 3448 22 to to IN cord-005646-xhx9pzhj 3448 23 previous previous JJ cord-005646-xhx9pzhj 3448 24 values value NNS cord-005646-xhx9pzhj 3448 25 after after IN cord-005646-xhx9pzhj 3448 26 24 24 CD cord-005646-xhx9pzhj 3448 27 hours hour NNS cord-005646-xhx9pzhj 3448 28 ( ( -LRB- cord-005646-xhx9pzhj 3448 29 p<0.005 p<0.005 CD cord-005646-xhx9pzhj 3448 30 ) ) -RRB- cord-005646-xhx9pzhj 3448 31 . . . cord-005646-xhx9pzhj 3449 1 72 72 CD cord-005646-xhx9pzhj 3449 2 hours hour NNS cord-005646-xhx9pzhj 3449 3 after after IN cord-005646-xhx9pzhj 3449 4 CPB CPB NNP cord-005646-xhx9pzhj 3449 5 , , , cord-005646-xhx9pzhj 3449 6 similar similar JJ cord-005646-xhx9pzhj 3449 7 values value NNS cord-005646-xhx9pzhj 3449 8 are be VBP cord-005646-xhx9pzhj 3449 9 observed observe VBN cord-005646-xhx9pzhj 3449 10 in in IN cord-005646-xhx9pzhj 3449 11 groups group NNS cord-005646-xhx9pzhj 3449 12 II II NNP cord-005646-xhx9pzhj 3449 13 and and CC cord-005646-xhx9pzhj 3449 14 Ill Ill NNP cord-005646-xhx9pzhj 3449 15 , , , cord-005646-xhx9pzhj 3449 16 but but CC cord-005646-xhx9pzhj 3449 17 there there EX cord-005646-xhx9pzhj 3449 18 is be VBZ cord-005646-xhx9pzhj 3449 19 a a DT cord-005646-xhx9pzhj 3449 20 further further JJ cord-005646-xhx9pzhj 3449 21 increase increase NN cord-005646-xhx9pzhj 3449 22 in in IN cord-005646-xhx9pzhj 3449 23 serum serum NN cord-005646-xhx9pzhj 3449 24 TNF tnf NN cord-005646-xhx9pzhj 3449 25 - - : cord-005646-xhx9pzhj 3449 26 a a DT cord-005646-xhx9pzhj 3449 27 levels level NNS cord-005646-xhx9pzhj 3449 28 in in IN cord-005646-xhx9pzhj 3449 29 group group NN cord-005646-xhx9pzhj 3450 1 I -PRON- PRP cord-005646-xhx9pzhj 3450 2 when when WRB cord-005646-xhx9pzhj 3450 3 compared compare VBN cord-005646-xhx9pzhj 3450 4 with with IN cord-005646-xhx9pzhj 3450 5 both both DT cord-005646-xhx9pzhj 3450 6 other other JJ cord-005646-xhx9pzhj 3450 7 groups group NNS cord-005646-xhx9pzhj 3450 8 ( ( -LRB- cord-005646-xhx9pzhj 3450 9 p<0.03 p<0.03 NN cord-005646-xhx9pzhj 3450 10 ) ) -RRB- cord-005646-xhx9pzhj 3450 11 . . . cord-005646-xhx9pzhj 3451 1 We -PRON- PRP cord-005646-xhx9pzhj 3451 2 found find VBD cord-005646-xhx9pzhj 3451 3 no no DT cord-005646-xhx9pzhj 3451 4 statistically statistically RB cord-005646-xhx9pzhj 3451 5 differences difference NNS cord-005646-xhx9pzhj 3451 6 in in IN cord-005646-xhx9pzhj 3451 7 any any DT cord-005646-xhx9pzhj 3451 8 other other JJ cord-005646-xhx9pzhj 3451 9 moment moment NN cord-005646-xhx9pzhj 3451 10 . . . cord-005646-xhx9pzhj 3452 1 There there EX cord-005646-xhx9pzhj 3452 2 was be VBD cord-005646-xhx9pzhj 3452 3 a a DT cord-005646-xhx9pzhj 3452 4 significant significant JJ cord-005646-xhx9pzhj 3452 5 correlation correlation NN cord-005646-xhx9pzhj 3452 6 between between IN cord-005646-xhx9pzhj 3452 7 serum serum NN cord-005646-xhx9pzhj 3452 8 TNF TNF NNP cord-005646-xhx9pzhj 3452 9 - - HYPH cord-005646-xhx9pzhj 3452 10 o o NN cord-005646-xhx9pzhj 3452 11 levels level NNS cord-005646-xhx9pzhj 3452 12 determined determine VBD cord-005646-xhx9pzhj 3452 13 72 72 CD cord-005646-xhx9pzhj 3452 14 hours hour NNS cord-005646-xhx9pzhj 3452 15 after after IN cord-005646-xhx9pzhj 3452 16 surgery surgery NN cord-005646-xhx9pzhj 3452 17 and and CC cord-005646-xhx9pzhj 3452 18 CPB CPB NNP cord-005646-xhx9pzhj 3452 19 duration duration NN cord-005646-xhx9pzhj 3452 20 ( ( -LRB- cord-005646-xhx9pzhj 3452 21 p<0,003 p<0,003 NN cord-005646-xhx9pzhj 3452 22 ) ) -RRB- cord-005646-xhx9pzhj 3452 23 . . . cord-005646-xhx9pzhj 3453 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3453 2 : : : cord-005646-xhx9pzhj 3454 1 CPB CPB NNP cord-005646-xhx9pzhj 3454 2 in in IN cord-005646-xhx9pzhj 3454 3 childhood childhood NN cord-005646-xhx9pzhj 3454 4 provokes provoke VBZ cord-005646-xhx9pzhj 3454 5 a a DT cord-005646-xhx9pzhj 3454 6 significant significant JJ cord-005646-xhx9pzhj 3454 7 increase increase NN cord-005646-xhx9pzhj 3454 8 in in IN cord-005646-xhx9pzhj 3454 9 serum serum NN cord-005646-xhx9pzhj 3454 10 TNFa TNFa NNS cord-005646-xhx9pzhj 3454 11 levels level NNS cord-005646-xhx9pzhj 3454 12 , , , cord-005646-xhx9pzhj 3454 13 In in IN cord-005646-xhx9pzhj 3454 14 newborns newborn NNS cord-005646-xhx9pzhj 3454 15 the the DT cord-005646-xhx9pzhj 3454 16 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3454 17 response response NN cord-005646-xhx9pzhj 3454 18 is be VBZ cord-005646-xhx9pzhj 3454 19 maintained maintain VBN cord-005646-xhx9pzhj 3454 20 72 72 CD cord-005646-xhx9pzhj 3454 21 hours hour NNS cord-005646-xhx9pzhj 3454 22 after after IN cord-005646-xhx9pzhj 3454 23 surgery surgery NN cord-005646-xhx9pzhj 3454 24 . . . cord-005646-xhx9pzhj 3455 1 This this DT cord-005646-xhx9pzhj 3455 2 enhancement enhancement NN cord-005646-xhx9pzhj 3455 3 of of IN cord-005646-xhx9pzhj 3455 4 serum serum NN cord-005646-xhx9pzhj 3455 5 TNF tnf NN cord-005646-xhx9pzhj 3455 6 - - HYPH cord-005646-xhx9pzhj 3455 7 e e NNP cord-005646-xhx9pzhj 3455 8 levels level NNS cord-005646-xhx9pzhj 3455 9 indicates indicate VBZ cord-005646-xhx9pzhj 3455 10 the the DT cord-005646-xhx9pzhj 3455 11 existence existence NN cord-005646-xhx9pzhj 3455 12 of of IN cord-005646-xhx9pzhj 3455 13 a a DT cord-005646-xhx9pzhj 3455 14 relevant relevant JJ cord-005646-xhx9pzhj 3455 15 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3455 16 response response NN cord-005646-xhx9pzhj 3455 17 in in IN cord-005646-xhx9pzhj 3455 18 these these DT cord-005646-xhx9pzhj 3455 19 patients patient NNS cord-005646-xhx9pzhj 3455 20 . . . cord-005646-xhx9pzhj 3456 1 Introduction introduction NN cord-005646-xhx9pzhj 3456 2 : : : cord-005646-xhx9pzhj 3457 1 Cardiac cardiac JJ cord-005646-xhx9pzhj 3457 2 surgery surgery NN cord-005646-xhx9pzhj 3457 3 appears appear VBZ cord-005646-xhx9pzhj 3457 4 to to TO cord-005646-xhx9pzhj 3457 5 induce induce VB cord-005646-xhx9pzhj 3457 6 a a DT cord-005646-xhx9pzhj 3457 7 systemic systemic JJ cord-005646-xhx9pzhj 3457 8 inflammatory inflammatory JJ cord-005646-xhx9pzhj 3457 9 response response NN cord-005646-xhx9pzhj 3457 10 . . . cord-005646-xhx9pzhj 3458 1 We -PRON- PRP cord-005646-xhx9pzhj 3458 2 have have VBP cord-005646-xhx9pzhj 3458 3 investigated investigate VBN cord-005646-xhx9pzhj 3458 4 the the DT cord-005646-xhx9pzhj 3458 5 behaviour behaviour NN cord-005646-xhx9pzhj 3458 6 of of IN cord-005646-xhx9pzhj 3458 7 IL-1 IL-1 NNP cord-005646-xhx9pzhj 3458 8 I~ I~ NNP cord-005646-xhx9pzhj 3458 9 and and CC cord-005646-xhx9pzhj 3458 10 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3458 11 before before IN cord-005646-xhx9pzhj 3458 12 and and CC cord-005646-xhx9pzhj 3458 13 after after IN cord-005646-xhx9pzhj 3458 14 cardiac cardiac JJ cord-005646-xhx9pzhj 3458 15 surgery surgery NN cord-005646-xhx9pzhj 3458 16 . . . cord-005646-xhx9pzhj 3459 1 Patients patient NNS cord-005646-xhx9pzhj 3459 2 and and CC cord-005646-xhx9pzhj 3459 3 methods method NNS cord-005646-xhx9pzhj 3459 4 : : : cord-005646-xhx9pzhj 3459 5 We -PRON- PRP cord-005646-xhx9pzhj 3459 6 studied study VBD cord-005646-xhx9pzhj 3459 7 serum serum NN cord-005646-xhx9pzhj 3459 8 IL-1 IL-1 NNP cord-005646-xhx9pzhj 3459 9 6 6 CD cord-005646-xhx9pzhj 3459 10 and and CC cord-005646-xhx9pzhj 3459 11 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3459 12 levels level NNS cord-005646-xhx9pzhj 3459 13 from from IN cord-005646-xhx9pzhj 3459 14 20 20 CD cord-005646-xhx9pzhj 3459 15 children child NNS cord-005646-xhx9pzhj 3459 16 with with IN cord-005646-xhx9pzhj 3459 17 congenital congenital JJ cord-005646-xhx9pzhj 3459 18 heart heart NN cord-005646-xhx9pzhj 3459 19 disease disease NN cord-005646-xhx9pzhj 3459 20 ( ( -LRB- cord-005646-xhx9pzhj 3459 21 10 10 CD cord-005646-xhx9pzhj 3459 22 boys boy NNS cord-005646-xhx9pzhj 3459 23 and and CC cord-005646-xhx9pzhj 3459 24 10 10 CD cord-005646-xhx9pzhj 3459 25 girls girl NNS cord-005646-xhx9pzhj 3459 26 ) ) -RRB- cord-005646-xhx9pzhj 3459 27 , , , cord-005646-xhx9pzhj 3459 28 aged age VBN cord-005646-xhx9pzhj 3459 29 from from IN cord-005646-xhx9pzhj 3459 30 7 7 CD cord-005646-xhx9pzhj 3459 31 days day NNS cord-005646-xhx9pzhj 3459 32 to to IN cord-005646-xhx9pzhj 3459 33 14 14 CD cord-005646-xhx9pzhj 3459 34 years year NNS cord-005646-xhx9pzhj 3459 35 , , , cord-005646-xhx9pzhj 3459 36 undergoing undergo VBG cord-005646-xhx9pzhj 3459 37 open open JJ cord-005646-xhx9pzhj 3459 38 heart heart NN cord-005646-xhx9pzhj 3459 39 surgery surgery NN cord-005646-xhx9pzhj 3459 40 , , , cord-005646-xhx9pzhj 3459 41 before before IN cord-005646-xhx9pzhj 3459 42 CPB CPB NNP cord-005646-xhx9pzhj 3459 43 ( ( -LRB- cord-005646-xhx9pzhj 3459 44 D D NNP cord-005646-xhx9pzhj 3459 45 We -PRON- PRP cord-005646-xhx9pzhj 3459 46 found find VBD cord-005646-xhx9pzhj 3459 47 no no DT cord-005646-xhx9pzhj 3459 48 statistically statistically RB cord-005646-xhx9pzhj 3459 49 differences difference NNS cord-005646-xhx9pzhj 3459 50 in in IN cord-005646-xhx9pzhj 3459 51 the the DT cord-005646-xhx9pzhj 3459 52 IL IL NNP cord-005646-xhx9pzhj 3459 53 - - HYPH cord-005646-xhx9pzhj 3459 54 I -PRON- PRP cord-005646-xhx9pzhj 3459 55 levels level NNS cord-005646-xhx9pzhj 3459 56 in in IN cord-005646-xhx9pzhj 3459 57 the the DT cord-005646-xhx9pzhj 3459 58 different different JJ cord-005646-xhx9pzhj 3459 59 groups group NNS cord-005646-xhx9pzhj 3459 60 and and CC cord-005646-xhx9pzhj 3459 61 moments moment NNS cord-005646-xhx9pzhj 3459 62 . . . cord-005646-xhx9pzhj 3460 1 There there EX cord-005646-xhx9pzhj 3460 2 is be VBZ cord-005646-xhx9pzhj 3460 3 a a DT cord-005646-xhx9pzhj 3460 4 significant significant JJ cord-005646-xhx9pzhj 3460 5 increase increase NN cord-005646-xhx9pzhj 3460 6 in in IN cord-005646-xhx9pzhj 3460 7 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3460 8 immediately immediately RB cord-005646-xhx9pzhj 3460 9 after after IN cord-005646-xhx9pzhj 3460 10 surgery surgery NN cord-005646-xhx9pzhj 3460 11 ( ( -LRB- cord-005646-xhx9pzhj 3460 12 p<0,01 p<0,01 NN cord-005646-xhx9pzhj 3460 13 ) ) -RRB- cord-005646-xhx9pzhj 3460 14 with with IN cord-005646-xhx9pzhj 3460 15 similar similar JJ cord-005646-xhx9pzhj 3460 16 levels level NNS cord-005646-xhx9pzhj 3460 17 24 24 CD cord-005646-xhx9pzhj 3460 18 hours hour NNS cord-005646-xhx9pzhj 3460 19 after after IN cord-005646-xhx9pzhj 3460 20 CPB CPB NNP cord-005646-xhx9pzhj 3460 21 and and CC cord-005646-xhx9pzhj 3460 22 a a DT cord-005646-xhx9pzhj 3460 23 significant significant JJ cord-005646-xhx9pzhj 3460 24 decrease decrease NN cord-005646-xhx9pzhj 3460 25 ( ( -LRB- cord-005646-xhx9pzhj 3460 26 p<0.01 p<0.01 NN cord-005646-xhx9pzhj 3460 27 ) ) -RRB- cord-005646-xhx9pzhj 3460 28 72 72 CD cord-005646-xhx9pzhj 3460 29 hours hour NNS cord-005646-xhx9pzhj 3460 30 after after IN cord-005646-xhx9pzhj 3460 31 CPB CPB NNP cord-005646-xhx9pzhj 3460 32 . . . cord-005646-xhx9pzhj 3461 1 Preoperatory Preoperatory NNP cord-005646-xhx9pzhj 3461 2 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3461 3 levels level NNS cord-005646-xhx9pzhj 3461 4 were be VBD cord-005646-xhx9pzhj 3461 5 higher high JJR cord-005646-xhx9pzhj 3461 6 in in IN cord-005646-xhx9pzhj 3461 7 the the DT cord-005646-xhx9pzhj 3461 8 groups group NNS cord-005646-xhx9pzhj 3461 9 I -PRON- PRP cord-005646-xhx9pzhj 3461 10 and and CC cord-005646-xhx9pzhj 3461 11 tl tl VBP cord-005646-xhx9pzhj 3461 12 than than IN cord-005646-xhx9pzhj 3461 13 in in IN cord-005646-xhx9pzhj 3461 14 group group NN cord-005646-xhx9pzhj 3461 15 I11 I11 NNP cord-005646-xhx9pzhj 3461 16 ( ( -LRB- cord-005646-xhx9pzhj 3461 17 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 3461 18 ) ) -RRB- cord-005646-xhx9pzhj 3461 19 . . . cord-005646-xhx9pzhj 3462 1 24 24 CD cord-005646-xhx9pzhj 3462 2 hours hour NNS cord-005646-xhx9pzhj 3462 3 after after IN cord-005646-xhx9pzhj 3462 4 CPB CPB NNP cord-005646-xhx9pzhj 3462 5 serum serum NN cord-005646-xhx9pzhj 3462 6 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3462 7 levels level NNS cord-005646-xhx9pzhj 3462 8 in in IN cord-005646-xhx9pzhj 3462 9 group group NN cord-005646-xhx9pzhj 3462 10 1 1 CD cord-005646-xhx9pzhj 3462 11 were be VBD cord-005646-xhx9pzhj 3462 12 significantly significantly RB cord-005646-xhx9pzhj 3462 13 higher high JJR cord-005646-xhx9pzhj 3462 14 when when WRB cord-005646-xhx9pzhj 3462 15 compared compare VBN cord-005646-xhx9pzhj 3462 16 with with IN cord-005646-xhx9pzhj 3462 17 group group NN cord-005646-xhx9pzhj 3462 18 111 111 CD cord-005646-xhx9pzhj 3462 19 ( ( -LRB- cord-005646-xhx9pzhj 3462 20 p<0.05 p<0.05 CD cord-005646-xhx9pzhj 3462 21 ) ) -RRB- cord-005646-xhx9pzhj 3462 22 . . . cord-005646-xhx9pzhj 3463 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3463 2 : : : cord-005646-xhx9pzhj 3464 1 CPB CPB NNP cord-005646-xhx9pzhj 3464 2 in in IN cord-005646-xhx9pzhj 3464 3 childhood childhood NN cord-005646-xhx9pzhj 3464 4 induces induce VBZ cord-005646-xhx9pzhj 3464 5 a a DT cord-005646-xhx9pzhj 3464 6 significant significant JJ cord-005646-xhx9pzhj 3464 7 transient transient JJ cord-005646-xhx9pzhj 3464 8 increase increase NN cord-005646-xhx9pzhj 3464 9 in in IN cord-005646-xhx9pzhj 3464 10 serum serum NN cord-005646-xhx9pzhj 3464 11 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3464 12 levels level NNS cord-005646-xhx9pzhj 3464 13 , , , cord-005646-xhx9pzhj 3464 14 strongly strongly RB cord-005646-xhx9pzhj 3464 15 relevant relevant JJ cord-005646-xhx9pzhj 3464 16 in in IN cord-005646-xhx9pzhj 3464 17 newborns newborn NNS cord-005646-xhx9pzhj 3464 18 . . . cord-005646-xhx9pzhj 3465 1 CPB CPB NNP cord-005646-xhx9pzhj 3465 2 was be VBD cord-005646-xhx9pzhj 3465 3 not not RB cord-005646-xhx9pzhj 3465 4 associated associate VBN cord-005646-xhx9pzhj 3465 5 to to IN cord-005646-xhx9pzhj 3465 6 a a DT cord-005646-xhx9pzhj 3465 7 significant significant JJ cord-005646-xhx9pzhj 3465 8 modification modification NN cord-005646-xhx9pzhj 3465 9 in in IN cord-005646-xhx9pzhj 3465 10 serum serum NN cord-005646-xhx9pzhj 3465 11 IL-1 IL-1 NNP cord-005646-xhx9pzhj 3465 12 6 6 CD cord-005646-xhx9pzhj 3465 13 levels level NNS cord-005646-xhx9pzhj 3465 14 . . . cord-005646-xhx9pzhj 3466 1 Thus thus RB cord-005646-xhx9pzhj 3466 2 , , , cord-005646-xhx9pzhj 3466 3 CPB CPB NNP cord-005646-xhx9pzhj 3466 4 in in IN cord-005646-xhx9pzhj 3466 5 childhood childhood NN cord-005646-xhx9pzhj 3466 6 induces induce VBZ cord-005646-xhx9pzhj 3466 7 a a DT cord-005646-xhx9pzhj 3466 8 dissociated dissociated JJ cord-005646-xhx9pzhj 3466 9 behaviour behaviour NN cord-005646-xhx9pzhj 3466 10 in in IN cord-005646-xhx9pzhj 3466 11 the the DT cord-005646-xhx9pzhj 3466 12 proinflammatory proinflammatory JJ cord-005646-xhx9pzhj 3466 13 IL-6 IL-6 NNP cord-005646-xhx9pzhj 3466 14 and and CC cord-005646-xhx9pzhj 3466 15 IL-1 IL-1 NNP cord-005646-xhx9pzhj 3466 16 & & CC cord-005646-xhx9pzhj 3466 17 pathways pathway NNS cord-005646-xhx9pzhj 3466 18 . . . cord-005646-xhx9pzhj 3467 1 Obiective obiective JJ cord-005646-xhx9pzhj 3467 2 , , , cord-005646-xhx9pzhj 3468 1 To to TO cord-005646-xhx9pzhj 3468 2 evaluate evaluate VB cord-005646-xhx9pzhj 3468 3 the the DT cord-005646-xhx9pzhj 3468 4 effects effect NNS cord-005646-xhx9pzhj 3468 5 of of IN cord-005646-xhx9pzhj 3468 6 AMG AMG NNP cord-005646-xhx9pzhj 3468 7 receipt receipt NN cord-005646-xhx9pzhj 3468 8 on on IN cord-005646-xhx9pzhj 3468 9 the the DT cord-005646-xhx9pzhj 3468 10 clinical clinical JJ cord-005646-xhx9pzhj 3468 11 condition condition NN cord-005646-xhx9pzhj 3468 12 during during IN cord-005646-xhx9pzhj 3468 13 the the DT cord-005646-xhx9pzhj 3468 14 first first JJ cord-005646-xhx9pzhj 3468 15 12 12 CD cord-005646-xhx9pzhj 3468 16 hours hour NNS cord-005646-xhx9pzhj 3468 17 after after IN cord-005646-xhx9pzhj 3468 18 birth birth NN cord-005646-xhx9pzhj 3468 19 ( ( -LRB- cord-005646-xhx9pzhj 3468 20 t2 t2 NNP cord-005646-xhx9pzhj 3468 21 ) ) -RRB- cord-005646-xhx9pzhj 3468 22 , , , cord-005646-xhx9pzhj 3468 23 the the DT cord-005646-xhx9pzhj 3468 24 morbidity morbidity NN cord-005646-xhx9pzhj 3468 25 and and CC cord-005646-xhx9pzhj 3468 26 mortality mortality NN cord-005646-xhx9pzhj 3468 27 in in IN cord-005646-xhx9pzhj 3468 28 immature immature JJ cord-005646-xhx9pzhj 3468 29 outborn outborn VBN cord-005646-xhx9pzhj 3468 30 neonates neonate NNS cord-005646-xhx9pzhj 3468 31 . . . cord-005646-xhx9pzhj 3469 1 Methods method NNS cord-005646-xhx9pzhj 3469 2 . . . cord-005646-xhx9pzhj 3470 1 We -PRON- PRP cord-005646-xhx9pzhj 3470 2 studied study VBD cord-005646-xhx9pzhj 3470 3 44 44 CD cord-005646-xhx9pzhj 3470 4 outborn outborn VBN cord-005646-xhx9pzhj 3470 5 neonates neonate NNS cord-005646-xhx9pzhj 3470 6 with with IN cord-005646-xhx9pzhj 3470 7 GA GA NNP cord-005646-xhx9pzhj 3470 8 26 26 CD cord-005646-xhx9pzhj 3470 9 to to IN cord-005646-xhx9pzhj 3470 10 29 29 CD cord-005646-xhx9pzhj 3470 11 wks wk NNS cord-005646-xhx9pzhj 3470 12 , , , cord-005646-xhx9pzhj 3470 13 admitted admit VBN cord-005646-xhx9pzhj 3470 14 during during IN cord-005646-xhx9pzhj 3470 15 the the DT cord-005646-xhx9pzhj 3470 16 years year NNS cord-005646-xhx9pzhj 3470 17 1993 1993 CD cord-005646-xhx9pzhj 3470 18 to to IN cord-005646-xhx9pzhj 3470 19 1995 1995 CD cord-005646-xhx9pzhj 3470 20 . . . cord-005646-xhx9pzhj 3471 1 Eighteen eighteen CD cord-005646-xhx9pzhj 3471 2 neonates neonate NNS cord-005646-xhx9pzhj 3471 3 exposed expose VBN cord-005646-xhx9pzhj 3471 4 to to IN cord-005646-xhx9pzhj 3471 5 AMG AMG NNP cord-005646-xhx9pzhj 3471 6 ( ( -LRB- cord-005646-xhx9pzhj 3471 7 GA:27,6+lwks GA:27,6+lwks NNP cord-005646-xhx9pzhj 3471 8 , , , cord-005646-xhx9pzhj 3471 9 BW BW NNP cord-005646-xhx9pzhj 3471 10 : : : cord-005646-xhx9pzhj 3471 11 1066_+195 1066_+195 CD cord-005646-xhx9pzhj 3471 12 g g NN cord-005646-xhx9pzhj 3471 13 ) ) -RRB- cord-005646-xhx9pzhj 3471 14 and and CC cord-005646-xhx9pzhj 3471 15 26 26 CD cord-005646-xhx9pzhj 3471 16 neonates neonate NNS cord-005646-xhx9pzhj 3471 17 did do VBD cord-005646-xhx9pzhj 3471 18 not not RB cord-005646-xhx9pzhj 3471 19 ( ( -LRB- cord-005646-xhx9pzhj 3471 20 GA GA NNP cord-005646-xhx9pzhj 3471 21 : : : cord-005646-xhx9pzhj 3471 22 27,7_+1wks 27,7_+1wks CD cord-005646-xhx9pzhj 3471 23 , , , cord-005646-xhx9pzhj 3471 24 BW BW NNP cord-005646-xhx9pzhj 3471 25 : : : cord-005646-xhx9pzhj 3471 26 1042_+187 1042_+187 CD cord-005646-xhx9pzhj 3471 27 g g NN cord-005646-xhx9pzhj 3471 28 ) ) -RRB- cord-005646-xhx9pzhj 3471 29 . . . cord-005646-xhx9pzhj 3472 1 Results result NNS cord-005646-xhx9pzhj 3472 2 . . . cord-005646-xhx9pzhj 3473 1 AMG AMG NNP cord-005646-xhx9pzhj 3473 2 - - HYPH cord-005646-xhx9pzhj 3473 3 exposed expose VBN cord-005646-xhx9pzhj 3473 4 neonates neonate NNS cord-005646-xhx9pzhj 3473 5 compared compare VBN cord-005646-xhx9pzhj 3473 6 to to IN cord-005646-xhx9pzhj 3473 7 those those DT cord-005646-xhx9pzhj 3473 8 not not RB cord-005646-xhx9pzhj 3473 9 exposed expose VBN cord-005646-xhx9pzhj 3473 10 had have VBD cord-005646-xhx9pzhj 3473 11 lower low JJR cord-005646-xhx9pzhj 3473 12 incidence incidence NN cord-005646-xhx9pzhj 3473 13 of of IN cord-005646-xhx9pzhj 3473 14 Apgar Apgar NNP cord-005646-xhx9pzhj 3473 15 score score NN cord-005646-xhx9pzhj 3473 16 at at IN cord-005646-xhx9pzhj 3473 17 5 5 CD cord-005646-xhx9pzhj 3473 18 min min NN cord-005646-xhx9pzhj 3473 19 _ _ NN cord-005646-xhx9pzhj 3473 20 < < XX cord-005646-xhx9pzhj 3473 21 3 3 CD cord-005646-xhx9pzhj 3473 22 ( ( -LRB- cord-005646-xhx9pzhj 3473 23 6 6 CD cord-005646-xhx9pzhj 3473 24 % % NN cord-005646-xhx9pzhj 3473 25 vs vs IN cord-005646-xhx9pzhj 3473 26 35 35 CD cord-005646-xhx9pzhj 3473 27 % % NN cord-005646-xhx9pzhj 3473 28 , , , cord-005646-xhx9pzhj 3473 29 p<.05 p<.05 NNP cord-005646-xhx9pzhj 3473 30 ) ) -RRB- cord-005646-xhx9pzhj 3473 31 , , , cord-005646-xhx9pzhj 3473 32 lower low JJR cord-005646-xhx9pzhj 3473 33 incidence incidence NN cord-005646-xhx9pzhj 3473 34 of of IN cord-005646-xhx9pzhj 3473 35 PH PH NNP cord-005646-xhx9pzhj 3473 36 t2 t2 NNP cord-005646-xhx9pzhj 3473 37 < < XX cord-005646-xhx9pzhj 3473 38 7.20 7.20 CD cord-005646-xhx9pzhj 3473 39 ( ( -LRB- cord-005646-xhx9pzhj 3473 40 11 11 CD cord-005646-xhx9pzhj 3473 41 % % NN cord-005646-xhx9pzhj 3473 42 vs vs IN cord-005646-xhx9pzhj 3473 43 48 48 CD cord-005646-xhx9pzhj 3473 44 % % NN cord-005646-xhx9pzhj 3473 45 , , , cord-005646-xhx9pzhj 3473 46 p<.05 p<.05 NNP cord-005646-xhx9pzhj 3473 47 ) ) -RRB- cord-005646-xhx9pzhj 3473 48 , , , cord-005646-xhx9pzhj 3473 49 decrease decrease VB cord-005646-xhx9pzhj 3473 50 need need NN cord-005646-xhx9pzhj 3473 51 of of IN cord-005646-xhx9pzhj 3473 52 bicarbonate bicarbonate NN cord-005646-xhx9pzhj 3473 53 12 12 CD cord-005646-xhx9pzhj 3473 54 ( ( -LRB- cord-005646-xhx9pzhj 3473 55 22 22 CD cord-005646-xhx9pzhj 3473 56 % % NN cord-005646-xhx9pzhj 3473 57 vs vs IN cord-005646-xhx9pzhj 3473 58 54 54 CD cord-005646-xhx9pzhj 3473 59 % % NN cord-005646-xhx9pzhj 3473 60 , , , cord-005646-xhx9pzhj 3473 61 p<.05 p<.05 NNP cord-005646-xhx9pzhj 3473 62 ) ) -RRB- cord-005646-xhx9pzhj 3473 63 , , , cord-005646-xhx9pzhj 3473 64 lower lower VB cord-005646-xhx9pzhj 3473 65 FIO212 FIO212 NNP cord-005646-xhx9pzhj 3473 66 ( ( -LRB- cord-005646-xhx9pzhj 3473 67 FiO212min>40 FiO212min>40 NNS cord-005646-xhx9pzhj 3473 68 : : : cord-005646-xhx9pzhj 3473 69 17 17 CD cord-005646-xhx9pzhj 3473 70 % % NN cord-005646-xhx9pzhj 3473 71 vs vs IN cord-005646-xhx9pzhj 3473 72 48 48 CD cord-005646-xhx9pzhj 3473 73 % % NN cord-005646-xhx9pzhj 3473 74 , , , cord-005646-xhx9pzhj 3473 75 p<.05 p<.05 JJ cord-005646-xhx9pzhj 3474 1 and and CC cord-005646-xhx9pzhj 3474 2 FiO212max fio212max VB cord-005646-xhx9pzhj 3474 3 > > XX cord-005646-xhx9pzhj 3475 1 80 80 CD cord-005646-xhx9pzhj 3475 2 : : : cord-005646-xhx9pzhj 3476 1 17 17 CD cord-005646-xhx9pzhj 3476 2 % % NN cord-005646-xhx9pzhj 3476 3 vs vs IN cord-005646-xhx9pzhj 3476 4 52 52 CD cord-005646-xhx9pzhj 3476 5 % % NN cord-005646-xhx9pzhj 3476 6 , , , cord-005646-xhx9pzhj 3476 7 p<.05 p<.05 NNP cord-005646-xhx9pzhj 3476 8 ) ) -RRB- cord-005646-xhx9pzhj 3476 9 , , , cord-005646-xhx9pzhj 3476 10 lower low JJR cord-005646-xhx9pzhj 3476 11 incidence incidence NN cord-005646-xhx9pzhj 3476 12 of of IN cord-005646-xhx9pzhj 3476 13 intubation intubation NN cord-005646-xhx9pzhj 3476 14 ( ( -LRB- cord-005646-xhx9pzhj 3476 15 67 67 CD cord-005646-xhx9pzhj 3476 16 % % NN cord-005646-xhx9pzhj 3476 17 vs vs IN cord-005646-xhx9pzhj 3476 18 92 92 CD cord-005646-xhx9pzhj 3476 19 % % NN cord-005646-xhx9pzhj 3476 20 , , , cord-005646-xhx9pzhj 3476 21 p<.05 p<.05 NNP cord-005646-xhx9pzhj 3476 22 ) ) -RRB- cord-005646-xhx9pzhj 3476 23 , , , cord-005646-xhx9pzhj 3476 24 lower low JJR cord-005646-xhx9pzhj 3476 25 requirements requirement NNS cord-005646-xhx9pzhj 3476 26 of of IN cord-005646-xhx9pzhj 3476 27 surfactant surfactant NN cord-005646-xhx9pzhj 3476 28 ( ( -LRB- cord-005646-xhx9pzhj 3476 29 50 50 CD cord-005646-xhx9pzhj 3476 30 % % NN cord-005646-xhx9pzhj 3476 31 vs vs IN cord-005646-xhx9pzhj 3476 32 79 79 CD cord-005646-xhx9pzhj 3476 33 % % NN cord-005646-xhx9pzhj 3476 34 , , , cord-005646-xhx9pzhj 3476 35 p<.05 p<.05 NNP cord-005646-xhx9pzhj 3476 36 ) ) -RRB- cord-005646-xhx9pzhj 3476 37 and and CC cord-005646-xhx9pzhj 3476 38 lower low JJR cord-005646-xhx9pzhj 3476 39 mortality mortality NN cord-005646-xhx9pzhj 3476 40 ( ( -LRB- cord-005646-xhx9pzhj 3476 41 11 11 CD cord-005646-xhx9pzhj 3476 42 % % NN cord-005646-xhx9pzhj 3476 43 vs vs IN cord-005646-xhx9pzhj 3476 44 50 50 CD cord-005646-xhx9pzhj 3476 45 % % NN cord-005646-xhx9pzhj 3476 46 p<.01 p<.01 JJ cord-005646-xhx9pzhj 3476 47 ) ) -RRB- cord-005646-xhx9pzhj 3476 48 . . . cord-005646-xhx9pzhj 3477 1 There there EX cord-005646-xhx9pzhj 3477 2 were be VBD cord-005646-xhx9pzhj 3477 3 no no DT cord-005646-xhx9pzhj 3477 4 differences difference NNS cord-005646-xhx9pzhj 3477 5 between between IN cord-005646-xhx9pzhj 3477 6 the the DT cord-005646-xhx9pzhj 3477 7 two two CD cord-005646-xhx9pzhj 3477 8 groups group NNS cord-005646-xhx9pzhj 3477 9 for for IN cord-005646-xhx9pzhj 3477 10 the the DT cord-005646-xhx9pzhj 3477 11 following follow VBG cord-005646-xhx9pzhj 3477 12 parameters parameter NNS cord-005646-xhx9pzhj 3477 13 : : : cord-005646-xhx9pzhj 3477 14 type type NN cord-005646-xhx9pzhj 3477 15 of of IN cord-005646-xhx9pzhj 3477 16 delivery delivery NN cord-005646-xhx9pzhj 3477 17 , , , cord-005646-xhx9pzhj 3477 18 hypothermia hypothermia NN cord-005646-xhx9pzhj 3477 19 hypoglycemia hypoglycemia NN cord-005646-xhx9pzhj 3477 20 and and CC cord-005646-xhx9pzhj 3477 21 anemia anemia NN cord-005646-xhx9pzhj 3477 22 during during IN cord-005646-xhx9pzhj 3477 23 admission admission NN cord-005646-xhx9pzhj 3477 24 , , , cord-005646-xhx9pzhj 3477 25 hypernatremia hypernatremia NN cord-005646-xhx9pzhj 3477 26 , , , cord-005646-xhx9pzhj 3477 27 hypotension hypotension NN cord-005646-xhx9pzhj 3477 28 12 12 CD cord-005646-xhx9pzhj 3477 29 ( ( -LRB- cord-005646-xhx9pzhj 3477 30 MAP<30mmHg MAP<30mmHg NNP cord-005646-xhx9pzhj 3477 31 ) ) -RRB- cord-005646-xhx9pzhj 3477 32 , , , cord-005646-xhx9pzhj 3477 33 need need NN cord-005646-xhx9pzhj 3477 34 of of IN cord-005646-xhx9pzhj 3477 35 dopamine dopamine NN cord-005646-xhx9pzhj 3477 36 and and CC cord-005646-xhx9pzhj 3477 37 or or CC cord-005646-xhx9pzhj 3477 38 plasma plasma NN cord-005646-xhx9pzhj 3477 39 12 12 CD cord-005646-xhx9pzhj 3477 40 , , , cord-005646-xhx9pzhj 3477 41 incidences incidence NNS cord-005646-xhx9pzhj 3477 42 of of IN cord-005646-xhx9pzhj 3477 43 PTX PTX NNP cord-005646-xhx9pzhj 3477 44 PDA PDA NNP cord-005646-xhx9pzhj 3477 45 sepsis sepsis NN cord-005646-xhx9pzhj 3477 46 NEC NEC NNP cord-005646-xhx9pzhj 3477 47 severe severe JJ cord-005646-xhx9pzhj 3477 48 ROP rop NN cord-005646-xhx9pzhj 3477 49 major major JJ cord-005646-xhx9pzhj 3477 50 IVH IVH NNP cord-005646-xhx9pzhj 3477 51 ( ( -LRB- cord-005646-xhx9pzhj 3477 52 plus plus CC cord-005646-xhx9pzhj 3477 53 PVL PVL NNP cord-005646-xhx9pzhj 3477 54 ) ) -RRB- cord-005646-xhx9pzhj 3477 55 and and CC cord-005646-xhx9pzhj 3477 56 BPD bpd NN cord-005646-xhx9pzhj 3477 57 and and CC cord-005646-xhx9pzhj 3477 58 duration duration NN cord-005646-xhx9pzhj 3477 59 of of IN cord-005646-xhx9pzhj 3477 60 intubation intubation NN cord-005646-xhx9pzhj 3477 61 . . . cord-005646-xhx9pzhj 3478 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3478 2 . . . cord-005646-xhx9pzhj 3479 1 The the DT cord-005646-xhx9pzhj 3479 2 main main JJ cord-005646-xhx9pzhj 3479 3 beneficial beneficial JJ cord-005646-xhx9pzhj 3479 4 effects effect NNS cord-005646-xhx9pzhj 3479 5 of of IN cord-005646-xhx9pzhj 3479 6 AMG AMG NNP cord-005646-xhx9pzhj 3479 7 receipt receipt NN cord-005646-xhx9pzhj 3479 8 on on IN cord-005646-xhx9pzhj 3479 9 the the DT cord-005646-xhx9pzhj 3479 10 immature immature JJ cord-005646-xhx9pzhj 3479 11 outborn outborn VBN cord-005646-xhx9pzhj 3479 12 neonates neonate NNS cord-005646-xhx9pzhj 3479 13 were be VBD cord-005646-xhx9pzhj 3479 14 the the DT cord-005646-xhx9pzhj 3479 15 decrease decrease NN cord-005646-xhx9pzhj 3479 16 of of IN cord-005646-xhx9pzhj 3479 17 mortality mortality NN cord-005646-xhx9pzhj 3479 18 and and CC cord-005646-xhx9pzhj 3479 19 the the DT cord-005646-xhx9pzhj 3479 20 decrease decrease NN cord-005646-xhx9pzhj 3479 21 of of IN cord-005646-xhx9pzhj 3479 22 surfactant surfactant NN cord-005646-xhx9pzhj 3479 23 need need NN cord-005646-xhx9pzhj 3479 24 . . . cord-005646-xhx9pzhj 3480 1 There there EX cord-005646-xhx9pzhj 3480 2 was be VBD cord-005646-xhx9pzhj 3480 3 no no DT cord-005646-xhx9pzhj 3480 4 effect effect NN cord-005646-xhx9pzhj 3480 5 of of IN cord-005646-xhx9pzhj 3480 6 AMG AMG NNP cord-005646-xhx9pzhj 3480 7 receipt receipt NN cord-005646-xhx9pzhj 3480 8 upon upon IN cord-005646-xhx9pzhj 3480 9 other other JJ cord-005646-xhx9pzhj 3480 10 severe severe JJ cord-005646-xhx9pzhj 3480 11 morbidity morbidity NN cord-005646-xhx9pzhj 3480 12 in in IN cord-005646-xhx9pzhj 3480 13 this this DT cord-005646-xhx9pzhj 3480 14 high high JJ cord-005646-xhx9pzhj 3480 15 risk risk NN cord-005646-xhx9pzhj 3480 16 group group NN cord-005646-xhx9pzhj 3480 17 of of IN cord-005646-xhx9pzhj 3480 18 neonates neonate NNS cord-005646-xhx9pzhj 3480 19 . . . cord-005646-xhx9pzhj 3481 1 Premature premature JJ cord-005646-xhx9pzhj 3481 2 babies baby NNS cord-005646-xhx9pzhj 3481 3 are be VBP cord-005646-xhx9pzhj 3481 4 very very RB cord-005646-xhx9pzhj 3481 5 sensitive sensitive JJ cord-005646-xhx9pzhj 3481 6 on on IN cord-005646-xhx9pzhj 3481 7 homeostatic homeostatic JJ cord-005646-xhx9pzhj 3481 8 disturbances disturbance NNS cord-005646-xhx9pzhj 3481 9 , , , cord-005646-xhx9pzhj 3481 10 and and CC cord-005646-xhx9pzhj 3481 11 often often RB cord-005646-xhx9pzhj 3481 12 develope develope VBP cord-005646-xhx9pzhj 3481 13 intracranial intracranial JJ cord-005646-xhx9pzhj 3481 14 haemorrhage haemorrhage NN cord-005646-xhx9pzhj 3481 15 ( ( -LRB- cord-005646-xhx9pzhj 3481 16 ICH ICH NNP cord-005646-xhx9pzhj 3481 17 ) ) -RRB- cord-005646-xhx9pzhj 3481 18 . . . cord-005646-xhx9pzhj 3482 1 Ultrasound ultrasound NN cord-005646-xhx9pzhj 3482 2 scan scan NN cord-005646-xhx9pzhj 3482 3 of of IN cord-005646-xhx9pzhj 3482 4 the the DT cord-005646-xhx9pzhj 3482 5 bram bram NNP cord-005646-xhx9pzhj 3482 6 shows show VBZ cord-005646-xhx9pzhj 3482 7 four four CD cord-005646-xhx9pzhj 3482 8 grades grade NNS cord-005646-xhx9pzhj 3482 9 of of IN cord-005646-xhx9pzhj 3482 10 ICH ICH NNP cord-005646-xhx9pzhj 3482 11 : : : cord-005646-xhx9pzhj 3483 1 -Grade -Grade NNP cord-005646-xhx9pzhj 3483 2 I -PRON- PRP cord-005646-xhx9pzhj 3483 3 -only -only RB cord-005646-xhx9pzhj 3484 1 periventricular periventricular NNP cord-005646-xhx9pzhj 3484 2 hyperechogenic hyperechogenic NNP cord-005646-xhx9pzhj 3484 3 areas area NNS cord-005646-xhx9pzhj 3484 4 -Grade -grade ADD cord-005646-xhx9pzhj 3485 1 II II NNP cord-005646-xhx9pzhj 3485 2 -haemorrhage -haemorrhage HYPH cord-005646-xhx9pzhj 3485 3 ham ham NNP cord-005646-xhx9pzhj 3486 1 the the DT cord-005646-xhx9pzhj 3486 2 lateral lateral JJ cord-005646-xhx9pzhj 3486 3 ventricles ventricles NNPS cord-005646-xhx9pzhj 3486 4 -Grade -Grade NNP cord-005646-xhx9pzhj 3486 5 IlI ili NN cord-005646-xhx9pzhj 3486 6 - - HYPH cord-005646-xhx9pzhj 3486 7 dilated dilate VBN cord-005646-xhx9pzhj 3486 8 lateral lateral JJ cord-005646-xhx9pzhj 3486 9 ventricles ventricle NNS cord-005646-xhx9pzhj 3487 1 -Gtrade -Gtrade . cord-005646-xhx9pzhj 3488 1 IV IV NNP cord-005646-xhx9pzhj 3488 2 -intracerebral -intracerebral JJ cord-005646-xhx9pzhj 3488 3 haemorrhage haemorrhage NN cord-005646-xhx9pzhj 3488 4 . . . cord-005646-xhx9pzhj 3489 1 The the DT cord-005646-xhx9pzhj 3489 2 purposes purpose NNS cord-005646-xhx9pzhj 3489 3 of of IN cord-005646-xhx9pzhj 3489 4 this this DT cord-005646-xhx9pzhj 3489 5 study study NN cord-005646-xhx9pzhj 3489 6 were be VBD cord-005646-xhx9pzhj 3489 7 : : : cord-005646-xhx9pzhj 3489 8 1 1 CD cord-005646-xhx9pzhj 3489 9 To to TO cord-005646-xhx9pzhj 3489 10 show show VB cord-005646-xhx9pzhj 3489 11 the the DT cord-005646-xhx9pzhj 3489 12 incidence incidence NN cord-005646-xhx9pzhj 3489 13 of of IN cord-005646-xhx9pzhj 3489 14 ICH ICH NNP cord-005646-xhx9pzhj 3489 15 in in IN cord-005646-xhx9pzhj 3489 16 premature premature JJ cord-005646-xhx9pzhj 3489 17 babies baby NNS cord-005646-xhx9pzhj 3489 18 and and CC cord-005646-xhx9pzhj 3489 19 its -PRON- PRP$ cord-005646-xhx9pzhj 3489 20 correlation correlation NN cord-005646-xhx9pzhj 3489 21 with with IN cord-005646-xhx9pzhj 3489 22 the the DT cord-005646-xhx9pzhj 3489 23 gestational gestational JJ cord-005646-xhx9pzhj 3489 24 age age NN cord-005646-xhx9pzhj 3489 25 , , , cord-005646-xhx9pzhj 3489 26 2 2 CD cord-005646-xhx9pzhj 3489 27 . . . cord-005646-xhx9pzhj 3490 1 To to TO cord-005646-xhx9pzhj 3490 2 determine determine VB cord-005646-xhx9pzhj 3490 3 the the DT cord-005646-xhx9pzhj 3490 4 severity severity NN cord-005646-xhx9pzhj 3490 5 of of IN cord-005646-xhx9pzhj 3490 6 ICH ICH NNP cord-005646-xhx9pzhj 3490 7 3 3 CD cord-005646-xhx9pzhj 3490 8 . . . cord-005646-xhx9pzhj 3491 1 To to TO cord-005646-xhx9pzhj 3491 2 present present VB cord-005646-xhx9pzhj 3491 3 the the DT cord-005646-xhx9pzhj 3491 4 outcome outcome NN cord-005646-xhx9pzhj 3491 5 & & CC cord-005646-xhx9pzhj 3491 6 those those DT cord-005646-xhx9pzhj 3491 7 babies baby NNS cord-005646-xhx9pzhj 3491 8 . . . cord-005646-xhx9pzhj 3492 1 In in IN cord-005646-xhx9pzhj 3492 2 the the DT cord-005646-xhx9pzhj 3492 3 study study NN cord-005646-xhx9pzhj 3492 4 were be VBD cord-005646-xhx9pzhj 3492 5 included include VBN cord-005646-xhx9pzhj 3492 6 393 393 CD cord-005646-xhx9pzhj 3492 7 premature premature JJ cord-005646-xhx9pzhj 3492 8 babies baby NNS cord-005646-xhx9pzhj 3492 9 successively successively RB cord-005646-xhx9pzhj 3492 10 - - HYPH cord-005646-xhx9pzhj 3492 11 born bear VBN cord-005646-xhx9pzhj 3492 12 at at IN cord-005646-xhx9pzhj 3492 13 the the DT cord-005646-xhx9pzhj 3492 14 Department Department NNP cord-005646-xhx9pzhj 3492 15 of of IN cord-005646-xhx9pzhj 3492 16 Gynecology Gynecology NNP cord-005646-xhx9pzhj 3492 17 and and CC cord-005646-xhx9pzhj 3492 18 Obstetrics Obstetrics NNP cord-005646-xhx9pzhj 3492 19 before before IN cord-005646-xhx9pzhj 3492 20 37 37 CD cord-005646-xhx9pzhj 3492 21 gestational gestational JJ cord-005646-xhx9pzhj 3492 22 week week NN cord-005646-xhx9pzhj 3492 23 ( ( -LRB- cord-005646-xhx9pzhj 3492 24 g.w g.w NNP cord-005646-xhx9pzhj 3492 25 . . NNP cord-005646-xhx9pzhj 3492 26 ) ) -RRB- cord-005646-xhx9pzhj 3492 27 and and CC cord-005646-xhx9pzhj 3492 28 grouped group VBN cord-005646-xhx9pzhj 3492 29 in in IN cord-005646-xhx9pzhj 3492 30 three three CD cord-005646-xhx9pzhj 3492 31 groups group NNS cord-005646-xhx9pzhj 3492 32 : : : cord-005646-xhx9pzhj 3492 33 less less JJR cord-005646-xhx9pzhj 3492 34 than than IN cord-005646-xhx9pzhj 3492 35 28 28 CD cord-005646-xhx9pzhj 3492 36 g.w g.w NNP cord-005646-xhx9pzhj 3492 37 . . NNP cord-005646-xhx9pzhj 3492 38 , , , cord-005646-xhx9pzhj 3492 39 28 28 CD cord-005646-xhx9pzhj 3492 40 - - SYM cord-005646-xhx9pzhj 3492 41 32 32 CD cord-005646-xhx9pzhj 3492 42 g.w g.w NNP cord-005646-xhx9pzhj 3492 43 . . NNP cord-005646-xhx9pzhj 3492 44 , , , cord-005646-xhx9pzhj 3492 45 33 33 CD cord-005646-xhx9pzhj 3492 46 - - SYM cord-005646-xhx9pzhj 3492 47 36 36 CD cord-005646-xhx9pzhj 3492 48 g.w g.w NN cord-005646-xhx9pzhj 3492 49 . . . cord-005646-xhx9pzhj 3493 1 To to IN cord-005646-xhx9pzhj 3493 2 all all DT cord-005646-xhx9pzhj 3493 3 of of IN cord-005646-xhx9pzhj 3493 4 them -PRON- PRP cord-005646-xhx9pzhj 3493 5 was be VBD cord-005646-xhx9pzhj 3493 6 performed perform VBN cord-005646-xhx9pzhj 3493 7 ultrasound ultrasound NN cord-005646-xhx9pzhj 3493 8 scan scan NN cord-005646-xhx9pzhj 3493 9 of of IN cord-005646-xhx9pzhj 3493 10 the the DT cord-005646-xhx9pzhj 3493 11 brain brain NN cord-005646-xhx9pzhj 3493 12 . . . cord-005646-xhx9pzhj 3494 1 Results result NNS cord-005646-xhx9pzhj 3494 2 : : : cord-005646-xhx9pzhj 3494 3 1 1 CD cord-005646-xhx9pzhj 3494 4 . . . cord-005646-xhx9pzhj 3495 1 The the DT cord-005646-xhx9pzhj 3495 2 incidence incidence NN cord-005646-xhx9pzhj 3495 3 of of IN cord-005646-xhx9pzhj 3495 4 ICH ICH NNP cord-005646-xhx9pzhj 3495 5 hi hi UH cord-005646-xhx9pzhj 3495 6 premature premature JJ cord-005646-xhx9pzhj 3495 7 babies baby NNS cord-005646-xhx9pzhj 3495 8 is be VBZ cord-005646-xhx9pzhj 3495 9 49 49 CD cord-005646-xhx9pzhj 3495 10 % % NN cord-005646-xhx9pzhj 3495 11 and and CC cord-005646-xhx9pzhj 3495 12 there there EX cord-005646-xhx9pzhj 3495 13 is be VBZ cord-005646-xhx9pzhj 3495 14 ingh ingh JJ cord-005646-xhx9pzhj 3495 15 level level NN cord-005646-xhx9pzhj 3495 16 of of IN cord-005646-xhx9pzhj 3495 17 correlation correlation NN cord-005646-xhx9pzhj 3495 18 with with IN cord-005646-xhx9pzhj 3495 19 the the DT cord-005646-xhx9pzhj 3495 20 gestational gestational JJ cord-005646-xhx9pzhj 3495 21 age age NN cord-005646-xhx9pzhj 3495 22 : : : cord-005646-xhx9pzhj 3496 1 -Babies -Babies NNPS cord-005646-xhx9pzhj 3497 1 born bear VBN cord-005646-xhx9pzhj 3497 2 before before IN cord-005646-xhx9pzhj 3497 3 28 28 CD cord-005646-xhx9pzhj 3497 4 t~ t~ CD cord-005646-xhx9pzhj 3497 5 g.w g.w NNP cord-005646-xhx9pzhj 3497 6 . . NNP cord-005646-xhx9pzhj 3497 7 have have VBP cord-005646-xhx9pzhj 3497 8 100 100 CD cord-005646-xhx9pzhj 3497 9 % % NN cord-005646-xhx9pzhj 3497 10 incidence incidence NN cord-005646-xhx9pzhj 3497 11 of of IN cord-005646-xhx9pzhj 3497 12 ICH ICH NNP cord-005646-xhx9pzhj 3497 13 and and CC cord-005646-xhx9pzhj 3497 14 graduated graduate VBD cord-005646-xhx9pzhj 3497 15 : : : cord-005646-xhx9pzhj 3498 1 I -PRON- PRP cord-005646-xhx9pzhj 3498 2 grade grade VBP cord-005646-xhx9pzhj 3498 3 -5 -5 NNP cord-005646-xhx9pzhj 3498 4 % % NN cord-005646-xhx9pzhj 3498 5 , , , cord-005646-xhx9pzhj 3498 6 II ii CD cord-005646-xhx9pzhj 3498 7 grade grade NN cord-005646-xhx9pzhj 3498 8 -65 -65 NNP cord-005646-xhx9pzhj 3498 9 % % NN cord-005646-xhx9pzhj 3498 10 , , , cord-005646-xhx9pzhj 3498 11 III iii CD cord-005646-xhx9pzhj 3498 12 grade grade NN cord-005646-xhx9pzhj 3498 13 -25 -25 NN cord-005646-xhx9pzhj 3498 14 % % NN cord-005646-xhx9pzhj 3498 15 , , , cord-005646-xhx9pzhj 3498 16 IV IV NNP cord-005646-xhx9pzhj 3498 17 grade grade NN cord-005646-xhx9pzhj 3498 18 -5 -5 NNP cord-005646-xhx9pzhj 3498 19 % % NN cord-005646-xhx9pzhj 3499 1 -Babies -babie VBZ cord-005646-xhx9pzhj 3499 2 old old JJ cord-005646-xhx9pzhj 3499 3 between between IN cord-005646-xhx9pzhj 3499 4 28 28 CD cord-005646-xhx9pzhj 3499 5 - - SYM cord-005646-xhx9pzhj 3499 6 32 32 CD cord-005646-xhx9pzhj 3499 7 g.w g.w NN cord-005646-xhx9pzhj 3499 8 . . . cord-005646-xhx9pzhj 3500 1 have have VBP cord-005646-xhx9pzhj 3500 2 incidence incidence NN cord-005646-xhx9pzhj 3500 3 of of IN cord-005646-xhx9pzhj 3500 4 61 61 CD cord-005646-xhx9pzhj 3500 5 % % NN cord-005646-xhx9pzhj 3501 1 : : : cord-005646-xhx9pzhj 3501 2 I -PRON- PRP cord-005646-xhx9pzhj 3501 3 grade grade NN cord-005646-xhx9pzhj 3501 4 -24 -24 DT cord-005646-xhx9pzhj 3501 5 % % NN cord-005646-xhx9pzhj 3501 6 , , , cord-005646-xhx9pzhj 3502 1 I -PRON- PRP cord-005646-xhx9pzhj 3502 2 [ [ -LRB- cord-005646-xhx9pzhj 3502 3 grade grade NN cord-005646-xhx9pzhj 3503 1 -62 -62 NN cord-005646-xhx9pzhj 3503 2 % % NN cord-005646-xhx9pzhj 3503 3 , , , cord-005646-xhx9pzhj 3503 4 III iii CD cord-005646-xhx9pzhj 3503 5 grade grade NN cord-005646-xhx9pzhj 3503 6 -14 -14 NNP cord-005646-xhx9pzhj 3503 7 % % NN cord-005646-xhx9pzhj 3503 8 . . . cord-005646-xhx9pzhj 3504 1 -Babies -babie VBZ cord-005646-xhx9pzhj 3504 2 older old JJR cord-005646-xhx9pzhj 3504 3 than than IN cord-005646-xhx9pzhj 3504 4 32 32 CD cord-005646-xhx9pzhj 3504 5 g.w g.w NNP cord-005646-xhx9pzhj 3504 6 . . NNP cord-005646-xhx9pzhj 3504 7 have have VBP cord-005646-xhx9pzhj 3504 8 incidence incidence NN cord-005646-xhx9pzhj 3504 9 of of IN cord-005646-xhx9pzhj 3504 10 33 33 CD cord-005646-xhx9pzhj 3504 11 % % NN cord-005646-xhx9pzhj 3504 12 : : : cord-005646-xhx9pzhj 3504 13 I -PRON- PRP cord-005646-xhx9pzhj 3504 14 grade grade NN cord-005646-xhx9pzhj 3504 15 -46 -46 NNP cord-005646-xhx9pzhj 3504 16 % % NN cord-005646-xhx9pzhj 3504 17 , , , cord-005646-xhx9pzhj 3504 18 Ii ii CD cord-005646-xhx9pzhj 3504 19 grade grade NN cord-005646-xhx9pzhj 3504 20 48 48 CD cord-005646-xhx9pzhj 3504 21 % % NN cord-005646-xhx9pzhj 3504 22 , , , cord-005646-xhx9pzhj 3504 23 III iii CD cord-005646-xhx9pzhj 3504 24 grade grade NN cord-005646-xhx9pzhj 3504 25 -6 -6 NNP cord-005646-xhx9pzhj 3504 26 % % NN cord-005646-xhx9pzhj 3504 27 2 2 CD cord-005646-xhx9pzhj 3504 28 . . . cord-005646-xhx9pzhj 3505 1 Sixty sixty CD cord-005646-xhx9pzhj 3505 2 of of IN cord-005646-xhx9pzhj 3505 3 393 393 CD cord-005646-xhx9pzhj 3505 4 premature premature JJ cord-005646-xhx9pzhj 3505 5 babies baby NNS cord-005646-xhx9pzhj 3505 6 have have VBP cord-005646-xhx9pzhj 3505 7 died die VBN cord-005646-xhx9pzhj 3505 8 and and CC cord-005646-xhx9pzhj 3505 9 it -PRON- PRP cord-005646-xhx9pzhj 3505 10 is be VBZ cord-005646-xhx9pzhj 3505 11 15.2 15.2 CD cord-005646-xhx9pzhj 3505 12 % % NN cord-005646-xhx9pzhj 3505 13 lethality lethality NN cord-005646-xhx9pzhj 3505 14 . . . cord-005646-xhx9pzhj 3506 1 In in IN cord-005646-xhx9pzhj 3506 2 all all DT cord-005646-xhx9pzhj 3506 3 died die VBN cord-005646-xhx9pzhj 3506 4 ilffant ilffant JJ cord-005646-xhx9pzhj 3506 5 was be VBD cord-005646-xhx9pzhj 3506 6 confirmed confirm VBN cord-005646-xhx9pzhj 3506 7 the the DT cord-005646-xhx9pzhj 3506 8 grade grade NN cord-005646-xhx9pzhj 3506 9 of of IN cord-005646-xhx9pzhj 3506 10 ICH ICH NNP cord-005646-xhx9pzhj 3506 11 diagnosed diagnose VBN cord-005646-xhx9pzhj 3506 12 by by IN cord-005646-xhx9pzhj 3506 13 ultrasotmd ultrasotmd NNP cord-005646-xhx9pzhj 3506 14 scan scan NN cord-005646-xhx9pzhj 3506 15 of of IN cord-005646-xhx9pzhj 3506 16 the the DT cord-005646-xhx9pzhj 3506 17 brain brain NN cord-005646-xhx9pzhj 3506 18 . . . cord-005646-xhx9pzhj 3507 1 D. D. NNP cord-005646-xhx9pzhj 3507 2 Maksimo~5c Maksimo~5c NNP cord-005646-xhx9pzhj 3507 3 . . . cord-005646-xhx9pzhj 3508 1 Z.Braiko Z.Braiko NNP cord-005646-xhx9pzhj 3508 2 ~ ~ CD cord-005646-xhx9pzhj 3508 3 ic ic XX cord-005646-xhx9pzhj 3509 1 , , , cord-005646-xhx9pzhj 3509 2 N.Vunjak N.Vunjak NNP cord-005646-xhx9pzhj 3509 3 . . . cord-005646-xhx9pzhj 3510 1 P. P. NNP cord-005646-xhx9pzhj 3510 2 Ivanovski Ivanovski NNP cord-005646-xhx9pzhj 3510 3 ( ( -LRB- cord-005646-xhx9pzhj 3510 4 5~iversi~ 5~iversi~ NNP cord-005646-xhx9pzhj 3510 5 , , , cord-005646-xhx9pzhj 3510 6 Children Children NNP cord-005646-xhx9pzhj 3510 7 's 's POS cord-005646-xhx9pzhj 3510 8 hospital hospital NN cord-005646-xhx9pzhj 3510 9 . . . cord-005646-xhx9pzhj 3511 1 Belgrade Belgrade NNP cord-005646-xhx9pzhj 3511 2 , , , cord-005646-xhx9pzhj 3511 3 Yugosla~ Yugosla~ NNP cord-005646-xhx9pzhj 3511 4 , , , cord-005646-xhx9pzhj 3511 5 ia ia NNP cord-005646-xhx9pzhj 3511 6 Infantile infantile JJ cord-005646-xhx9pzhj 3511 7 intracranial intracranial JJ cord-005646-xhx9pzhj 3511 8 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 3511 9 is be VBZ cord-005646-xhx9pzhj 3511 10 the the DT cord-005646-xhx9pzhj 3511 11 most most RBS cord-005646-xhx9pzhj 3511 12 frequent frequent JJ cord-005646-xhx9pzhj 3511 13 and and CC cord-005646-xhx9pzhj 3511 14 serious serious JJ cord-005646-xhx9pzhj 3511 15 manifestation manifestation NN cord-005646-xhx9pzhj 3511 16 of of IN cord-005646-xhx9pzhj 3511 17 late late JJ cord-005646-xhx9pzhj 3511 18 hemorrhagic hemorrhagic JJ cord-005646-xhx9pzhj 3511 19 disease disease NN cord-005646-xhx9pzhj 3511 20 of of IN cord-005646-xhx9pzhj 3511 21 the the DT cord-005646-xhx9pzhj 3511 22 newborn newborn NN cord-005646-xhx9pzhj 3511 23 caused cause VBN cord-005646-xhx9pzhj 3511 24 by by IN cord-005646-xhx9pzhj 3511 25 , , , cord-005646-xhx9pzhj 3511 26 , , , cord-005646-xhx9pzhj 3511 27 ~tamm ~tamm XX cord-005646-xhx9pzhj 3512 1 K K NNP cord-005646-xhx9pzhj 3512 2 deficiency deficiency NN cord-005646-xhx9pzhj 3512 3 in in IN cord-005646-xhx9pzhj 3512 4 earl earl NNP cord-005646-xhx9pzhj 3512 5 ? ? . cord-005646-xhx9pzhj 3513 1 , , , cord-005646-xhx9pzhj 3513 2 , , , cord-005646-xhx9pzhj 3513 3 ti ti NNP cord-005646-xhx9pzhj 3513 4 ~ ~ NFP cord-005646-xhx9pzhj 3513 5 fancy fancy NN cord-005646-xhx9pzhj 3513 6 . . . cord-005646-xhx9pzhj 3514 1 In in IN cord-005646-xhx9pzhj 3514 2 the the DT cord-005646-xhx9pzhj 3514 3 last last JJ cord-005646-xhx9pzhj 3514 4 two two CD cord-005646-xhx9pzhj 3514 5 years year NNS cord-005646-xhx9pzhj 3514 6 , , , cord-005646-xhx9pzhj 3514 7 we -PRON- PRP cord-005646-xhx9pzhj 3514 8 recorded record VBD cord-005646-xhx9pzhj 3514 9 five five CD cord-005646-xhx9pzhj 3514 10 cases case NNS cord-005646-xhx9pzhj 3514 11 of of IN cord-005646-xhx9pzhj 3514 12 infantile infantile JJ cord-005646-xhx9pzhj 3514 13 intracranial intracranial JJ cord-005646-xhx9pzhj 3514 14 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 3514 15 due due IN cord-005646-xhx9pzhj 3514 16 to to IN cord-005646-xhx9pzhj 3514 17 " " `` cord-005646-xhx9pzhj 3514 18 dtamin dtamin NNP cord-005646-xhx9pzhj 3514 19 K K NNP cord-005646-xhx9pzhj 3514 20 deficiency deficiency NN cord-005646-xhx9pzhj 3514 21 , , , cord-005646-xhx9pzhj 3514 22 despite despite IN cord-005646-xhx9pzhj 3515 1 routine routine JJ cord-005646-xhx9pzhj 3515 2 prophylax prophylax NNP cord-005646-xhx9pzhj 3515 3 ~ ~ NFP cord-005646-xhx9pzhj 3515 4 s s NNP cord-005646-xhx9pzhj 3515 5 ( ( -LRB- cord-005646-xhx9pzhj 3515 6 intramuscular intramuscular JJ cord-005646-xhx9pzhj 3515 7 Vitamin vitamin NN cord-005646-xhx9pzhj 3515 8 K K NNP cord-005646-xhx9pzhj 3515 9 , , , cord-005646-xhx9pzhj 3515 10 1 1 CD cord-005646-xhx9pzhj 3515 11 mg mg CD cord-005646-xhx9pzhj 3515 12 ) ) -RRB- cord-005646-xhx9pzhj 3515 13 , , , cord-005646-xhx9pzhj 3515 14 with with IN cord-005646-xhx9pzhj 3515 15 Bpieal Bpieal NNP cord-005646-xhx9pzhj 3515 16 clinical clinical JJ cord-005646-xhx9pzhj 3515 17 presentation presentation NN cord-005646-xhx9pzhj 3515 18 : : : cord-005646-xhx9pzhj 3515 19 age age NN cord-005646-xhx9pzhj 3515 20 was be VBD cord-005646-xhx9pzhj 3515 21 18 18 CD cord-005646-xhx9pzhj 3515 22 -65 -65 NN cord-005646-xhx9pzhj 3515 23 days day NNS cord-005646-xhx9pzhj 3515 24 ( ( -LRB- cord-005646-xhx9pzhj 3515 25 average average JJ cord-005646-xhx9pzhj 3515 26 40 40 CD cord-005646-xhx9pzhj 3515 27 days day NNS cord-005646-xhx9pzhj 3515 28 ) ) -RRB- cord-005646-xhx9pzhj 3515 29 : : : cord-005646-xhx9pzhj 3515 30 vomiting vomit VBG cord-005646-xhx9pzhj 3515 31 , , , cord-005646-xhx9pzhj 3515 32 poor poor JJ cord-005646-xhx9pzhj 3515 33 feeding feeding NN cord-005646-xhx9pzhj 3515 34 , , , cord-005646-xhx9pzhj 3515 35 lethar~'irritabilJty lethar~'irritabilJty NNS cord-005646-xhx9pzhj 3515 36 , , , cord-005646-xhx9pzhj 3515 37 palor palor NNP cord-005646-xhx9pzhj 3515 38 , , , cord-005646-xhx9pzhj 3515 39 bulging bulge VBG cord-005646-xhx9pzhj 3515 40 t0ntanelle t0ntanelle NNP cord-005646-xhx9pzhj 3515 41 and and CC cord-005646-xhx9pzhj 3515 42 convatsiones convatsione NNS cord-005646-xhx9pzhj 3515 43 were be VBD cord-005646-xhx9pzhj 3515 44 present present JJ cord-005646-xhx9pzhj 3515 45 in in IN cord-005646-xhx9pzhj 3515 46 most most JJS cord-005646-xhx9pzhj 3515 47 cases case NNS cord-005646-xhx9pzhj 3515 48 . . . cord-005646-xhx9pzhj 3516 1 Two two CD cord-005646-xhx9pzhj 3516 2 patients patient NNS cord-005646-xhx9pzhj 3516 3 developed develop VBD cord-005646-xhx9pzhj 3516 4 signs sign NNS cord-005646-xhx9pzhj 3516 5 of of IN cord-005646-xhx9pzhj 3516 6 hemorrhagic hemorrhagic JJ cord-005646-xhx9pzhj 3516 7 shock shock NN cord-005646-xhx9pzhj 3516 8 , , , cord-005646-xhx9pzhj 3516 9 with with IN cord-005646-xhx9pzhj 3516 10 hemoglobin hemoglobin NN cord-005646-xhx9pzhj 3516 11 level level NN cord-005646-xhx9pzhj 3516 12 less less JJR cord-005646-xhx9pzhj 3516 13 than than IN cord-005646-xhx9pzhj 3516 14 70 70 CD cord-005646-xhx9pzhj 3516 15 g.1 g.1 CD cord-005646-xhx9pzhj 3516 16 . . . cord-005646-xhx9pzhj 3517 1 In in IN cord-005646-xhx9pzhj 3517 2 3~5 3~5 CD cord-005646-xhx9pzhj 3517 3 F F NNP cord-005646-xhx9pzhj 3517 4 \qI \qi JJ cord-005646-xhx9pzhj 3517 5 level level NN cord-005646-xhx9pzhj 3517 6 was be VBD cord-005646-xhx9pzhj 3517 7 less less JJR cord-005646-xhx9pzhj 3517 8 than than IN cord-005646-xhx9pzhj 3517 9 30 30 CD cord-005646-xhx9pzhj 3517 10 % % NN cord-005646-xhx9pzhj 3517 11 of of IN cord-005646-xhx9pzhj 3517 12 predicted predict VBN cord-005646-xhx9pzhj 3517 13 value value NN cord-005646-xhx9pzhj 3517 14 . . . cord-005646-xhx9pzhj 3518 1 There there EX cord-005646-xhx9pzhj 3518 2 was be VBD cord-005646-xhx9pzhj 3518 3 no no DT cord-005646-xhx9pzhj 3518 4 evidence evidence NN cord-005646-xhx9pzhj 3518 5 of of IN cord-005646-xhx9pzhj 3518 6 head head NN cord-005646-xhx9pzhj 3518 7 trauma trauma NN cord-005646-xhx9pzhj 3518 8 or or CC cord-005646-xhx9pzhj 3518 9 liver liver NN cord-005646-xhx9pzhj 3518 10 disease disease NN cord-005646-xhx9pzhj 3518 11 in in IN cord-005646-xhx9pzhj 3518 12 none none NN cord-005646-xhx9pzhj 3518 13 of of IN cord-005646-xhx9pzhj 3518 14 patients patient NNS cord-005646-xhx9pzhj 3518 15 . . . cord-005646-xhx9pzhj 3519 1 Four four CD cord-005646-xhx9pzhj 3519 2 inlants inlant NNS cord-005646-xhx9pzhj 3519 3 were be VBD cord-005646-xhx9pzhj 3519 4 breast breast NN cord-005646-xhx9pzhj 3519 5 fed feed VBN cord-005646-xhx9pzhj 3519 6 , , , cord-005646-xhx9pzhj 3519 7 while while IN cord-005646-xhx9pzhj 3519 8 one one CD cord-005646-xhx9pzhj 3519 9 , , , cord-005646-xhx9pzhj 3519 10 who who WP cord-005646-xhx9pzhj 3519 11 had have VBD cord-005646-xhx9pzhj 3519 12 diarrheal diarrheal JJ cord-005646-xhx9pzhj 3519 13 disea.se disea.se CD cord-005646-xhx9pzhj 3519 14 , , , cord-005646-xhx9pzhj 3519 15 was be VBD cord-005646-xhx9pzhj 3519 16 on on IN cord-005646-xhx9pzhj 3519 17 adapted adapt VBN cord-005646-xhx9pzhj 3519 18 milk milk NN cord-005646-xhx9pzhj 3519 19 formula formula NN cord-005646-xhx9pzhj 3519 20 . . . cord-005646-xhx9pzhj 3520 1 Routine routine JJ cord-005646-xhx9pzhj 3520 2 therapy therapy NN cord-005646-xhx9pzhj 3520 3 wa.s wa.s NN cord-005646-xhx9pzhj 3520 4 given give VBN cord-005646-xhx9pzhj 3520 5 ( ( -LRB- cord-005646-xhx9pzhj 3520 6 including include VBG cord-005646-xhx9pzhj 3520 7 Vitamin vitamin NN cord-005646-xhx9pzhj 3520 8 K K NNP cord-005646-xhx9pzhj 3520 9 and and CC cord-005646-xhx9pzhj 3520 10 fresh fresh JJ cord-005646-xhx9pzhj 3520 11 frozen frozen JJ cord-005646-xhx9pzhj 3520 12 plasma plasma NN cord-005646-xhx9pzhj 3520 13 ) ) -RRB- cord-005646-xhx9pzhj 3520 14 . . . cord-005646-xhx9pzhj 3521 1 Two two CD cord-005646-xhx9pzhj 3521 2 patients patient NNS cord-005646-xhx9pzhj 3521 3 were be VBD cord-005646-xhx9pzhj 3521 4 discharged discharge VBN cord-005646-xhx9pzhj 3521 5 with with IN cord-005646-xhx9pzhj 3521 6 no no DT cord-005646-xhx9pzhj 3521 7 sequellae sequellae NNS cord-005646-xhx9pzhj 3521 8 , , , cord-005646-xhx9pzhj 3521 9 one one CD cord-005646-xhx9pzhj 3521 10 developed develop VBN cord-005646-xhx9pzhj 3521 11 posthemon'hagic posthemon'hagic NN cord-005646-xhx9pzhj 3521 12 hydrocephalus hydrocephalus NN cord-005646-xhx9pzhj 3521 13 as as IN cord-005646-xhx9pzhj 3521 14 a a DT cord-005646-xhx9pzhj 3521 15 complication complication NN cord-005646-xhx9pzhj 3521 16 and and CC cord-005646-xhx9pzhj 3521 17 two two CD cord-005646-xhx9pzhj 3521 18 patients patient NNS cord-005646-xhx9pzhj 3521 19 died die VBD cord-005646-xhx9pzhj 3521 20 . . . cord-005646-xhx9pzhj 3522 1 Late late JJ cord-005646-xhx9pzhj 3522 2 hemorrhagic hemorrhagic JJ cord-005646-xhx9pzhj 3522 3 diseo.se diseo.se NN cord-005646-xhx9pzhj 3522 4 of of IN cord-005646-xhx9pzhj 3522 5 the the DT cord-005646-xhx9pzhj 3522 6 newborn newborn NN cord-005646-xhx9pzhj 3522 7 is be VBZ cord-005646-xhx9pzhj 3522 8 sill/ sill/ NNS cord-005646-xhx9pzhj 3522 9 a a DT cord-005646-xhx9pzhj 3522 10 significant significant JJ cord-005646-xhx9pzhj 3522 11 cause cause NN cord-005646-xhx9pzhj 3522 12 of of IN cord-005646-xhx9pzhj 3522 13 morbidiB morbidiB NNP cord-005646-xhx9pzhj 3522 14 ' ' '' cord-005646-xhx9pzhj 3522 15 and and CC cord-005646-xhx9pzhj 3522 16 mortality mortality NN cord-005646-xhx9pzhj 3522 17 in in IN cord-005646-xhx9pzhj 3522 18 earl3 earl3 NN cord-005646-xhx9pzhj 3522 19 ' ' '' cord-005646-xhx9pzhj 3522 20 infancy infancy NN cord-005646-xhx9pzhj 3522 21 , , , cord-005646-xhx9pzhj 3522 22 despite despite IN cord-005646-xhx9pzhj 3522 23 different different JJ cord-005646-xhx9pzhj 3522 24 approaches approach NNS cord-005646-xhx9pzhj 3522 25 to to IN cord-005646-xhx9pzhj 3522 26 prophylaxis prophylaxis NN cord-005646-xhx9pzhj 3522 27 developed develop VBN cord-005646-xhx9pzhj 3522 28 in in IN cord-005646-xhx9pzhj 3522 29 recent recent JJ cord-005646-xhx9pzhj 3522 30 years year NNS cord-005646-xhx9pzhj 3522 31 . . . cord-005646-xhx9pzhj 3523 1 Background background NN cord-005646-xhx9pzhj 3523 2 : : : cord-005646-xhx9pzhj 3524 1 Neonatal neonatal JJ cord-005646-xhx9pzhj 3524 2 hearing hearing NN cord-005646-xhx9pzhj 3524 3 screening screening NN cord-005646-xhx9pzhj 3524 4 in in RP cord-005646-xhx9pzhj 3524 5 at at IN cord-005646-xhx9pzhj 3524 6 risk risk NN cord-005646-xhx9pzhj 3524 7 newborns newborn NNS cord-005646-xhx9pzhj 3524 8 can can MD cord-005646-xhx9pzhj 3524 9 detect detect VB cord-005646-xhx9pzhj 3524 10 50 50 CD cord-005646-xhx9pzhj 3524 11 % % NN cord-005646-xhx9pzhj 3524 12 of of IN cord-005646-xhx9pzhj 3524 13 the the DT cord-005646-xhx9pzhj 3524 14 children child NNS cord-005646-xhx9pzhj 3524 15 with with IN cord-005646-xhx9pzhj 3524 16 a a DT cord-005646-xhx9pzhj 3524 17 congenital congenital JJ cord-005646-xhx9pzhj 3524 18 hearing hearing NN cord-005646-xhx9pzhj 3524 19 loss loss NN cord-005646-xhx9pzhj 3524 20 . . . cord-005646-xhx9pzhj 3525 1 Automated automated JJ cord-005646-xhx9pzhj 3525 2 ABR ABR NNP cord-005646-xhx9pzhj 3525 3 hearing hearing NN cord-005646-xhx9pzhj 3525 4 screening screening NN cord-005646-xhx9pzhj 3525 5 ( ( -LRB- cord-005646-xhx9pzhj 3525 6 ALGO-1 ALGO-1 NNP cord-005646-xhx9pzhj 3525 7 ) ) -RRB- cord-005646-xhx9pzhj 3525 8 has have VBZ cord-005646-xhx9pzhj 3525 9 been be VBN cord-005646-xhx9pzhj 3525 10 introduced introduce VBN cord-005646-xhx9pzhj 3525 11 for for IN cord-005646-xhx9pzhj 3525 12 healthy healthy JJ cord-005646-xhx9pzhj 3525 13 newborns newborn NNS cord-005646-xhx9pzhj 3525 14 . . . cord-005646-xhx9pzhj 3526 1 The the DT cord-005646-xhx9pzhj 3526 2 aim aim NN cord-005646-xhx9pzhj 3526 3 of of IN cord-005646-xhx9pzhj 3526 4 this this DT cord-005646-xhx9pzhj 3526 5 study study NN cord-005646-xhx9pzhj 3526 6 is be VBZ cord-005646-xhx9pzhj 3526 7 to to TO cord-005646-xhx9pzhj 3526 8 test test VB cord-005646-xhx9pzhj 3526 9 the the DT cord-005646-xhx9pzhj 3526 10 validity validity NN cord-005646-xhx9pzhj 3526 11 of of IN cord-005646-xhx9pzhj 3526 12 this this DT cord-005646-xhx9pzhj 3526 13 ALGO-1 algo-1 JJ cord-005646-xhx9pzhj 3526 14 screener screener NN cord-005646-xhx9pzhj 3526 15 in in IN cord-005646-xhx9pzhj 3526 16 at at IN cord-005646-xhx9pzhj 3526 17 risk risk NN cord-005646-xhx9pzhj 3526 18 newborns newborn NNS cord-005646-xhx9pzhj 3526 19 in in IN cord-005646-xhx9pzhj 3526 20 a a DT cord-005646-xhx9pzhj 3526 21 neonatal neonatal JJ cord-005646-xhx9pzhj 3526 22 intensive intensive JJ cord-005646-xhx9pzhj 3526 23 care care NN cord-005646-xhx9pzhj 3526 24 unit unit NN cord-005646-xhx9pzhj 3526 25 . . . cord-005646-xhx9pzhj 3527 1 Subjects subject NNS cord-005646-xhx9pzhj 3527 2 : : : cord-005646-xhx9pzhj 3527 3 250 250 CD cord-005646-xhx9pzhj 3527 4 at at IN cord-005646-xhx9pzhj 3527 5 risk risk NN cord-005646-xhx9pzhj 3527 6 newborns newborn NNS cord-005646-xhx9pzhj 3527 7 ( ( -LRB- cord-005646-xhx9pzhj 3527 8 median median JJ cord-005646-xhx9pzhj 3527 9 gest.age gest.age NN cord-005646-xhx9pzhj 3527 10 : : : cord-005646-xhx9pzhj 3527 11 30.0 30.0 CD cord-005646-xhx9pzhj 3527 12 wks wks NN cord-005646-xhx9pzhj 3527 13 , , , cord-005646-xhx9pzhj 3527 14 median median JJ cord-005646-xhx9pzhj 3527 15 birthweight birthweight JJ cord-005646-xhx9pzhj 3527 16 1350 1350 CD cord-005646-xhx9pzhj 3527 17 g g NN cord-005646-xhx9pzhj 3527 18 ) ) -RRB- cord-005646-xhx9pzhj 3527 19 selected select VBN cord-005646-xhx9pzhj 3527 20 according accord VBG cord-005646-xhx9pzhj 3527 21 to to IN cord-005646-xhx9pzhj 3527 22 the the DT cord-005646-xhx9pzhj 3527 23 criteria criterion NNS cord-005646-xhx9pzhj 3527 24 of of IN cord-005646-xhx9pzhj 3527 25 the the DT cord-005646-xhx9pzhj 3527 26 American American NNP cord-005646-xhx9pzhj 3527 27 Joint Joint NNP cord-005646-xhx9pzhj 3527 28 Committee Committee NNP cord-005646-xhx9pzhj 3527 29 on on IN cord-005646-xhx9pzhj 3527 30 Infant Infant NNP cord-005646-xhx9pzhj 3527 31 Hearing hearing NN cord-005646-xhx9pzhj 3527 32 . . . cord-005646-xhx9pzhj 3528 1 Interventions intervention NNS cord-005646-xhx9pzhj 3528 2 : : : cord-005646-xhx9pzhj 3529 1 ALGO- ALGO- NNP cord-005646-xhx9pzhj 3530 1 I -PRON- PRP cord-005646-xhx9pzhj 3530 2 automated automate VBD cord-005646-xhx9pzhj 3530 3 ABR ABR NNP cord-005646-xhx9pzhj 3530 4 - - HYPH cord-005646-xhx9pzhj 3530 5 hearing hearing NN cord-005646-xhx9pzhj 3530 6 screening screening NN cord-005646-xhx9pzhj 3530 7 at at IN cord-005646-xhx9pzhj 3530 8 a a DT cord-005646-xhx9pzhj 3530 9 level level NN cord-005646-xhx9pzhj 3530 10 of of IN cord-005646-xhx9pzhj 3530 11 35 35 CD cord-005646-xhx9pzhj 3530 12 dB dB NNS cord-005646-xhx9pzhj 3530 13 was be VBD cord-005646-xhx9pzhj 3530 14 performed perform VBN cord-005646-xhx9pzhj 3530 15 in in IN cord-005646-xhx9pzhj 3530 16 the the DT cord-005646-xhx9pzhj 3530 17 neonatal neonatal JJ cord-005646-xhx9pzhj 3530 18 intensive intensive JJ cord-005646-xhx9pzhj 3530 19 care care NN cord-005646-xhx9pzhj 3530 20 unit unit NN cord-005646-xhx9pzhj 3530 21 . . . cord-005646-xhx9pzhj 3531 1 When when WRB cord-005646-xhx9pzhj 3531 2 bilaterally bilaterally RB cord-005646-xhx9pzhj 3531 3 referred refer VBN cord-005646-xhx9pzhj 3531 4 , , , cord-005646-xhx9pzhj 3531 5 further further JJ cord-005646-xhx9pzhj 3531 6 audiologic audiologic NN cord-005646-xhx9pzhj 3531 7 screening screening NN cord-005646-xhx9pzhj 3531 8 and/or and/or CC cord-005646-xhx9pzhj 3531 9 therapeutic therapeutic JJ cord-005646-xhx9pzhj 3531 10 intervention intervention NN cord-005646-xhx9pzhj 3531 11 took take VBD cord-005646-xhx9pzhj 3531 12 place place NN cord-005646-xhx9pzhj 3531 13 . . . cord-005646-xhx9pzhj 3532 1 When when WRB cord-005646-xhx9pzhj 3532 2 passed pass VBN cord-005646-xhx9pzhj 3532 3 uni uni NN cord-005646-xhx9pzhj 3532 4 - - : cord-005646-xhx9pzhj 3532 5 or or CC cord-005646-xhx9pzhj 3532 6 bilaterally bilaterally RB cord-005646-xhx9pzhj 3532 7 , , , cord-005646-xhx9pzhj 3532 8 children child NNS cord-005646-xhx9pzhj 3532 9 enrolled enrol VBD cord-005646-xhx9pzhj 3532 10 in in IN cord-005646-xhx9pzhj 3532 11 a a DT cord-005646-xhx9pzhj 3532 12 ) ) -RRB- cord-005646-xhx9pzhj 3532 13 a a DT cord-005646-xhx9pzhj 3532 14 nation nation NN cord-005646-xhx9pzhj 3532 15 wide wide JJ cord-005646-xhx9pzhj 3532 16 screening screening NN cord-005646-xhx9pzhj 3532 17 programme programme NN cord-005646-xhx9pzhj 3532 18 ( ( -LRB- cord-005646-xhx9pzhj 3532 19 EWlNG ewlng NN cord-005646-xhx9pzhj 3532 20 ) ) -RRB- cord-005646-xhx9pzhj 3532 21 at at IN cord-005646-xhx9pzhj 3532 22 the the DT cord-005646-xhx9pzhj 3532 23 age age NN cord-005646-xhx9pzhj 3532 24 of of IN cord-005646-xhx9pzhj 3532 25 9 9 CD cord-005646-xhx9pzhj 3532 26 months month NNS cord-005646-xhx9pzhj 3532 27 and and CC cord-005646-xhx9pzhj 3532 28 b b LS cord-005646-xhx9pzhj 3532 29 ) ) -RRB- cord-005646-xhx9pzhj 3532 30 in in IN cord-005646-xhx9pzhj 3532 31 a a DT cord-005646-xhx9pzhj 3532 32 half half NN cord-005646-xhx9pzhj 3532 33 yearly yearly JJ cord-005646-xhx9pzhj 3532 34 follow follow NN cord-005646-xhx9pzhj 3532 35 - - HYPH cord-005646-xhx9pzhj 3532 36 up up NN cord-005646-xhx9pzhj 3532 37 programme programme NN cord-005646-xhx9pzhj 3532 38 in in IN cord-005646-xhx9pzhj 3532 39 which which WDT cord-005646-xhx9pzhj 3532 40 hearing hearing NN cord-005646-xhx9pzhj 3532 41 and and CC cord-005646-xhx9pzhj 3532 42 speech speech NN cord-005646-xhx9pzhj 3532 43 - - HYPH cord-005646-xhx9pzhj 3532 44 and and CC cord-005646-xhx9pzhj 3532 45 language language NN cord-005646-xhx9pzhj 3532 46 development development NN cord-005646-xhx9pzhj 3532 47 were be VBD cord-005646-xhx9pzhj 3532 48 observed observe VBN cord-005646-xhx9pzhj 3532 49 according accord VBG cord-005646-xhx9pzhj 3532 50 to to IN cord-005646-xhx9pzhj 3532 51 Egan Egan NNP cord-005646-xhx9pzhj 3532 52 an an DT cord-005646-xhx9pzhj 3532 53 Illingworth Illingworth NNP cord-005646-xhx9pzhj 3532 54 . . . cord-005646-xhx9pzhj 3533 1 Results result NNS cord-005646-xhx9pzhj 3533 2 : : : cord-005646-xhx9pzhj 3534 1 Screening screen VBG cord-005646-xhx9pzhj 3534 2 without without IN cord-005646-xhx9pzhj 3534 3 disturbance disturbance NN cord-005646-xhx9pzhj 3534 4 from from IN cord-005646-xhx9pzhj 3534 5 ambient ambient JJ cord-005646-xhx9pzhj 3534 6 noise noise NN cord-005646-xhx9pzhj 3534 7 or or CC cord-005646-xhx9pzhj 3534 8 from from IN cord-005646-xhx9pzhj 3534 9 routine routine JJ cord-005646-xhx9pzhj 3534 10 technical technical JJ cord-005646-xhx9pzhj 3534 11 equipment equipment NN cord-005646-xhx9pzhj 3534 12 was be VBD cord-005646-xhx9pzhj 3534 13 possible possible JJ cord-005646-xhx9pzhj 3534 14 in in IN cord-005646-xhx9pzhj 3534 15 the the DT cord-005646-xhx9pzhj 3534 16 incubator incubator NN cord-005646-xhx9pzhj 3534 17 , , , cord-005646-xhx9pzhj 3534 18 even even RB cord-005646-xhx9pzhj 3534 19 during during IN cord-005646-xhx9pzhj 3534 20 nasal nasal JJ cord-005646-xhx9pzhj 3534 21 CPAP cpap NN cord-005646-xhx9pzhj 3534 22 therapy therapy NN cord-005646-xhx9pzhj 3534 23 . . . cord-005646-xhx9pzhj 3535 1 245 245 CD cord-005646-xhx9pzhj 3535 2 ( ( -LRB- cord-005646-xhx9pzhj 3535 3 98 98 CD cord-005646-xhx9pzhj 3535 4 % % NN cord-005646-xhx9pzhj 3535 5 ) ) -RRB- cord-005646-xhx9pzhj 3536 1 Newborns newborn NNS cord-005646-xhx9pzhj 3536 2 passed pass VBD cord-005646-xhx9pzhj 3536 3 ALGO-1 ALGO-1 NNP cord-005646-xhx9pzhj 3536 4 screening screening NN cord-005646-xhx9pzhj 3536 5 . . . cord-005646-xhx9pzhj 3537 1 5 5 LS cord-005646-xhx9pzhj 3537 2 ( ( -LRB- cord-005646-xhx9pzhj 3537 3 2 2 CD cord-005646-xhx9pzhj 3537 4 % % NN cord-005646-xhx9pzhj 3537 5 ) ) -RRB- cord-005646-xhx9pzhj 3537 6 did do VBD cord-005646-xhx9pzhj 3537 7 not not RB cord-005646-xhx9pzhj 3537 8 pass pass VB cord-005646-xhx9pzhj 3537 9 bilaterally bilaterally RB cord-005646-xhx9pzhj 3537 10 . . . cord-005646-xhx9pzhj 3538 1 1 1 CD cord-005646-xhx9pzhj 3538 2 of of IN cord-005646-xhx9pzhj 3538 3 5 5 CD cord-005646-xhx9pzhj 3538 4 with with IN cord-005646-xhx9pzhj 3538 5 a a DT cord-005646-xhx9pzhj 3538 6 congenital congenital JJ cord-005646-xhx9pzhj 3538 7 rubella rubella NN cord-005646-xhx9pzhj 3538 8 died die VBD cord-005646-xhx9pzhj 3538 9 shortly shortly RB cord-005646-xhx9pzhj 3538 10 after after IN cord-005646-xhx9pzhj 3538 11 screening screen VBG cord-005646-xhx9pzhj 3538 12 . . . cord-005646-xhx9pzhj 3539 1 In in IN cord-005646-xhx9pzhj 3539 2 4 4 CD cord-005646-xhx9pzhj 3539 3 of of IN cord-005646-xhx9pzhj 3539 4 5 5 CD cord-005646-xhx9pzhj 3539 5 bilateral bilateral JJ cord-005646-xhx9pzhj 3539 6 congenital congenital JJ cord-005646-xhx9pzhj 3539 7 hearing hearing NN cord-005646-xhx9pzhj 3539 8 loss loss NN cord-005646-xhx9pzhj 3539 9 of of IN cord-005646-xhx9pzhj 3539 10 ->35 ->35 CD cord-005646-xhx9pzhj 3539 11 dB db NN cord-005646-xhx9pzhj 3539 12 was be VBD cord-005646-xhx9pzhj 3539 13 confirmed confirm VBN cord-005646-xhx9pzhj 3539 14 . . . cord-005646-xhx9pzhj 3540 1 235 235 CD cord-005646-xhx9pzhj 3540 2 of of IN cord-005646-xhx9pzhj 3540 3 the the DT cord-005646-xhx9pzhj 3540 4 newborns newborn NNS cord-005646-xhx9pzhj 3540 5 passed pass VBN cord-005646-xhx9pzhj 3540 6 were be VBD cord-005646-xhx9pzhj 3540 7 still still RB cord-005646-xhx9pzhj 3540 8 alive alive JJ cord-005646-xhx9pzhj 3540 9 at at IN cord-005646-xhx9pzhj 3540 10 the the DT cord-005646-xhx9pzhj 3540 11 age age NN cord-005646-xhx9pzhj 3540 12 of of IN cord-005646-xhx9pzhj 3540 13 1 1 CD cord-005646-xhx9pzhj 3540 14 year year NN cord-005646-xhx9pzhj 3540 15 . . . cord-005646-xhx9pzhj 3541 1 Ewing Ewing NNP cord-005646-xhx9pzhj 3541 2 screening screening NN cord-005646-xhx9pzhj 3541 3 was be VBD cord-005646-xhx9pzhj 3541 4 performed perform VBN cord-005646-xhx9pzhj 3541 5 in in IN cord-005646-xhx9pzhj 3541 6 183 183 CD cord-005646-xhx9pzhj 3541 7 of of IN cord-005646-xhx9pzhj 3541 8 235 235 CD cord-005646-xhx9pzhj 3541 9 ( ( -LRB- cord-005646-xhx9pzhj 3541 10 77,9 77,9 CD cord-005646-xhx9pzhj 3541 11 % % NN cord-005646-xhx9pzhj 3541 12 ) ) -RRB- cord-005646-xhx9pzhj 3541 13 . . . cord-005646-xhx9pzhj 3542 1 161/183 161/183 CD cord-005646-xhx9pzhj 3542 2 passed pass VBD cord-005646-xhx9pzhj 3542 3 , , , cord-005646-xhx9pzhj 3542 4 15 15 CD cord-005646-xhx9pzhj 3542 5 of of IN cord-005646-xhx9pzhj 3542 6 183 183 CD cord-005646-xhx9pzhj 3542 7 had have VBD cord-005646-xhx9pzhj 3542 8 passagere passagere FW cord-005646-xhx9pzhj 3542 9 conductive conductive JJ cord-005646-xhx9pzhj 3542 10 hearing hearing NN cord-005646-xhx9pzhj 3542 11 loss loss NN cord-005646-xhx9pzhj 3542 12 , , , cord-005646-xhx9pzhj 3542 13 in in IN cord-005646-xhx9pzhj 3542 14 7/183 7/183 CD cord-005646-xhx9pzhj 3543 1 no no DT cord-005646-xhx9pzhj 3543 2 further further JJ cord-005646-xhx9pzhj 3543 3 investigation investigation NN cord-005646-xhx9pzhj 3543 4 was be VBD cord-005646-xhx9pzhj 3543 5 performed perform VBN cord-005646-xhx9pzhj 3543 6 . . . cord-005646-xhx9pzhj 3544 1 All all DT cord-005646-xhx9pzhj 3544 2 235 235 CD cord-005646-xhx9pzhj 3544 3 children child NNS cord-005646-xhx9pzhj 3544 4 enrolled enrol VBN cord-005646-xhx9pzhj 3544 5 in in IN cord-005646-xhx9pzhj 3544 6 the the DT cord-005646-xhx9pzhj 3544 7 I/2 I/2 NNP cord-005646-xhx9pzhj 3544 8 yearly yearly JJ cord-005646-xhx9pzhj 3544 9 follow follow NN cord-005646-xhx9pzhj 3544 10 - - HYPH cord-005646-xhx9pzhj 3544 11 up up NN cord-005646-xhx9pzhj 3544 12 programme programme NN cord-005646-xhx9pzhj 3544 13 had have VBD cord-005646-xhx9pzhj 3544 14 normal normal JJ cord-005646-xhx9pzhj 3544 15 speech speech NN cord-005646-xhx9pzhj 3544 16 - - HYPH cord-005646-xhx9pzhj 3544 17 and and CC cord-005646-xhx9pzhj 3544 18 language language NN cord-005646-xhx9pzhj 3544 19 development development NN cord-005646-xhx9pzhj 3544 20 . . . cord-005646-xhx9pzhj 3545 1 In in IN cord-005646-xhx9pzhj 3545 2 this this DT cord-005646-xhx9pzhj 3545 3 study study NN cord-005646-xhx9pzhj 3545 4 all all DT cord-005646-xhx9pzhj 3545 5 4 4 CD cord-005646-xhx9pzhj 3545 6 at at IN cord-005646-xhx9pzhj 3545 7 risk risk NN cord-005646-xhx9pzhj 3545 8 newborns newborn NNS cord-005646-xhx9pzhj 3545 9 with with IN cord-005646-xhx9pzhj 3545 10 bilateral bilateral JJ cord-005646-xhx9pzhj 3545 11 congeni congeni NNP cord-005646-xhx9pzhj 3545 12 " " '' cord-005646-xhx9pzhj 3545 13 tai tai NNP cord-005646-xhx9pzhj 3545 14 hearing hearing NN cord-005646-xhx9pzhj 3545 15 loss loss NN cord-005646-xhx9pzhj 3545 16 were be VBD cord-005646-xhx9pzhj 3545 17 detected detect VBN cord-005646-xhx9pzhj 3545 18 with with IN cord-005646-xhx9pzhj 3545 19 ALGO-1 ALGO-1 NNP cord-005646-xhx9pzhj 3545 20 screening screening NN cord-005646-xhx9pzhj 3545 21 . . . cord-005646-xhx9pzhj 3546 1 Screening screening NN cord-005646-xhx9pzhj 3546 2 results result NNS cord-005646-xhx9pzhj 3546 3 showed show VBD cord-005646-xhx9pzhj 3546 4 no no DT cord-005646-xhx9pzhj 3546 5 false false JJ cord-005646-xhx9pzhj 3546 6 negatives negative NNS cord-005646-xhx9pzhj 3546 7 at at IN cord-005646-xhx9pzhj 3546 8 follow follow NN cord-005646-xhx9pzhj 3546 9 - - HYPH cord-005646-xhx9pzhj 3546 10 up up NN cord-005646-xhx9pzhj 3546 11 . . . cord-005646-xhx9pzhj 3547 1 The the DT cord-005646-xhx9pzhj 3547 2 ALGO-1 ALGO-1 NNP cord-005646-xhx9pzhj 3547 3 infant infant NN cord-005646-xhx9pzhj 3547 4 hearing hearing NN cord-005646-xhx9pzhj 3547 5 screener screener NN cord-005646-xhx9pzhj 3547 6 can can MD cord-005646-xhx9pzhj 3547 7 be be VB cord-005646-xhx9pzhj 3547 8 used use VBN cord-005646-xhx9pzhj 3547 9 as as IN cord-005646-xhx9pzhj 3547 10 an an DT cord-005646-xhx9pzhj 3547 11 valid valid JJ cord-005646-xhx9pzhj 3547 12 automated automate VBN cord-005646-xhx9pzhj 3547 13 ABR ABR NNP cord-005646-xhx9pzhj 3547 14 - - HYPH cord-005646-xhx9pzhj 3547 15 screener screener NN cord-005646-xhx9pzhj 3547 16 to to TO cord-005646-xhx9pzhj 3547 17 detect detect VB cord-005646-xhx9pzhj 3547 18 hearing hearing NN cord-005646-xhx9pzhj 3547 19 loss loss NN cord-005646-xhx9pzhj 3547 20 in in RP cord-005646-xhx9pzhj 3547 21 at at IN cord-005646-xhx9pzhj 3547 22 risk risk NN cord-005646-xhx9pzhj 3547 23 newborns newborn NNS cord-005646-xhx9pzhj 3547 24 in in IN cord-005646-xhx9pzhj 3547 25 a a DT cord-005646-xhx9pzhj 3547 26 neonatal neonatal JJ cord-005646-xhx9pzhj 3547 27 intensive intensive JJ cord-005646-xhx9pzhj 3547 28 care care NN cord-005646-xhx9pzhj 3547 29 unit unit NN cord-005646-xhx9pzhj 3547 30 . . . cord-005646-xhx9pzhj 3547 31 _SP cord-005646-xhx9pzhj 3548 1 Gancia Gancia NNP cord-005646-xhx9pzhj 3548 2 GP GP NNP cord-005646-xhx9pzhj 3548 3 , , , cord-005646-xhx9pzhj 3548 4 Bruschi Bruschi NNP cord-005646-xhx9pzhj 3548 5 L L NNP cord-005646-xhx9pzhj 3548 6 Pnlito Pnlito NNP cord-005646-xhx9pzhj 3548 7 E E NNP cord-005646-xhx9pzhj 3548 8 , , , cord-005646-xhx9pzhj 3548 9 Ferrari Ferrari NNP cord-005646-xhx9pzhj 3548 10 G G NNP cord-005646-xhx9pzhj 3548 11 , , , cord-005646-xhx9pzhj 3548 12 Rondini Rondini NNP cord-005646-xhx9pzhj 3548 13 G g NN cord-005646-xhx9pzhj 3548 14 -Divisione -divisione NN cord-005646-xhx9pzhj 3548 15 di di NNP cord-005646-xhx9pzhj 3548 16 Patologia Patologia NNP cord-005646-xhx9pzhj 3548 17 Nc Nc NNP cord-005646-xhx9pzhj 3549 1 ~matate ~matate NFP cord-005646-xhx9pzhj 3549 2 e e NN cord-005646-xhx9pzhj 3549 3 Turapia Turapia NNP cord-005646-xhx9pzhj 3549 4 Intensiva Intensiva NNP cord-005646-xhx9pzhj 3549 5 -IRCCS -IRCCS NNP cord-005646-xhx9pzhj 3550 1 Policlinico Policlinico NNP cord-005646-xhx9pzhj 3550 2 S. S. NNP cord-005646-xhx9pzhj 3550 3 Mattco Mattco NNP cord-005646-xhx9pzhj 3551 1 -Pavia -Pavia . cord-005646-xhx9pzhj 3552 1 , , , cord-005646-xhx9pzhj 3552 2 Italy Italy NNP cord-005646-xhx9pzhj 3552 3 latrogenic latrogenic NNP cord-005646-xhx9pzhj 3552 4 esophageal esophageal JJ cord-005646-xhx9pzhj 3552 5 perforations perforation NNS cord-005646-xhx9pzhj 3552 6 ( ( -LRB- cord-005646-xhx9pzhj 3552 7 IEP IEP NNP cord-005646-xhx9pzhj 3552 8 ) ) -RRB- cord-005646-xhx9pzhj 3552 9 in in IN cord-005646-xhx9pzhj 3552 10 preterm preterm NNS cord-005646-xhx9pzhj 3552 11 and and CC cord-005646-xhx9pzhj 3552 12 term term NN cord-005646-xhx9pzhj 3552 13 infants infant NNS cord-005646-xhx9pzhj 3552 14 are be VBP cord-005646-xhx9pzhj 3552 15 seldom seldom RB cord-005646-xhx9pzhj 3552 16 reported report VBN cord-005646-xhx9pzhj 3552 17 in in IN cord-005646-xhx9pzhj 3552 18 litteraturc litteraturc NNP cord-005646-xhx9pzhj 3552 19 , , , cord-005646-xhx9pzhj 3552 20 in in IN cord-005646-xhx9pzhj 3552 21 association association NN cord-005646-xhx9pzhj 3552 22 with with IN cord-005646-xhx9pzhj 3552 23 difficult difficult JJ cord-005646-xhx9pzhj 3552 24 endotracheal endotracheal NN cord-005646-xhx9pzhj 3552 25 ( ( -LRB- cord-005646-xhx9pzhj 3552 26 ET et NN cord-005646-xhx9pzhj 3552 27 ) ) -RRB- cord-005646-xhx9pzhj 3552 28 intubation intubation NN cord-005646-xhx9pzhj 3552 29 ( ( -LRB- cord-005646-xhx9pzhj 3552 30 with with IN cord-005646-xhx9pzhj 3552 31 or or CC cord-005646-xhx9pzhj 3552 32 without without IN cord-005646-xhx9pzhj 3552 33 stylets stylet NNS cord-005646-xhx9pzhj 3552 34 ) ) -RRB- cord-005646-xhx9pzhj 3552 35 , , , cord-005646-xhx9pzhj 3552 36 insertion insertion NN cord-005646-xhx9pzhj 3552 37 of of IN cord-005646-xhx9pzhj 3552 38 gastric gastric JJ cord-005646-xhx9pzhj 3552 39 tube tube NN cord-005646-xhx9pzhj 3552 40 , , , cord-005646-xhx9pzhj 3552 41 and and CC cord-005646-xhx9pzhj 3552 42 pharyngeal pharyngeal JJ cord-005646-xhx9pzhj 3552 43 suctioning suctioning NN cord-005646-xhx9pzhj 3552 44 with with IN cord-005646-xhx9pzhj 3552 45 stiff stiff JJ cord-005646-xhx9pzhj 3552 46 catheters catheter NNS cord-005646-xhx9pzhj 3552 47 . . . cord-005646-xhx9pzhj 3553 1 Crieopharyngeal crieopharyngeal NN cord-005646-xhx9pzhj 3553 2 muscle muscle NN cord-005646-xhx9pzhj 3553 3 spasm spasm NN cord-005646-xhx9pzhj 3553 4 caused cause VBN cord-005646-xhx9pzhj 3553 5 by by IN cord-005646-xhx9pzhj 3553 6 instrumentation instrumentation NN cord-005646-xhx9pzhj 3553 7 may may MD cord-005646-xhx9pzhj 3553 8 also also RB cord-005646-xhx9pzhj 3553 9 lead lead VB cord-005646-xhx9pzhj 3553 10 m m NNP cord-005646-xhx9pzhj 3553 11 a a DT cord-005646-xhx9pzhj 3553 12 narrowing narrowing NN cord-005646-xhx9pzhj 3553 13 of of IN cord-005646-xhx9pzhj 3553 14 lumen lumen NN cord-005646-xhx9pzhj 3553 15 , , , cord-005646-xhx9pzhj 3553 16 with with IN cord-005646-xhx9pzhj 3553 17 increased increase VBN cord-005646-xhx9pzhj 3553 18 risk risk NN cord-005646-xhx9pzhj 3553 19 of of IN cord-005646-xhx9pzhj 3553 20 local local JJ cord-005646-xhx9pzhj 3553 21 injury injury NN cord-005646-xhx9pzhj 3553 22 . . . cord-005646-xhx9pzhj 3554 1 We -PRON- PRP cord-005646-xhx9pzhj 3554 2 report report VBP cord-005646-xhx9pzhj 3554 3 4 4 CD cord-005646-xhx9pzhj 3554 4 IEP IEP NNP cord-005646-xhx9pzhj 3554 5 observed observe VBD cord-005646-xhx9pzhj 3554 6 in in IN cord-005646-xhx9pzhj 3554 7 intubatcd intubatcd NNP cord-005646-xhx9pzhj 3554 8 , , , cord-005646-xhx9pzhj 3554 9 mechanically mechanically RB cord-005646-xhx9pzhj 3554 10 ventilated ventilate VBN cord-005646-xhx9pzhj 3554 11 newborn newborn JJ cord-005646-xhx9pzhj 3554 12 infants infant NNS cord-005646-xhx9pzhj 3554 13 ( ( -LRB- cord-005646-xhx9pzhj 3554 14 2 2 CD cord-005646-xhx9pzhj 3554 15 male male NN cord-005646-xhx9pzhj 3554 16 , , , cord-005646-xhx9pzhj 3554 17 2 2 CD cord-005646-xhx9pzhj 3554 18 female female NN cord-005646-xhx9pzhj 3554 19 , , , cord-005646-xhx9pzhj 3554 20 all all DT cord-005646-xhx9pzhj 3554 21 outborn outborn JJ cord-005646-xhx9pzhj 3554 22 ) ) -RRB- cord-005646-xhx9pzhj 3554 23 . . . cord-005646-xhx9pzhj 3555 1 A a DT cord-005646-xhx9pzhj 3555 2 common common JJ cord-005646-xhx9pzhj 3555 3 feature feature NN cord-005646-xhx9pzhj 3555 4 of of IN cord-005646-xhx9pzhj 3555 5 IEP IEP NNP cord-005646-xhx9pzhj 3555 6 was be VBD cord-005646-xhx9pzhj 3555 7 inability inability NN cord-005646-xhx9pzhj 3555 8 to to TO cord-005646-xhx9pzhj 3555 9 pass pass VB cord-005646-xhx9pzhj 3555 10 a a DT cord-005646-xhx9pzhj 3555 11 nasogastric nasogastric NN cord-005646-xhx9pzhj 3555 12 ( ( -LRB- cord-005646-xhx9pzhj 3555 13 NG ng NN cord-005646-xhx9pzhj 3555 14 ) ) -RRB- cord-005646-xhx9pzhj 3555 15 tube tube NN cord-005646-xhx9pzhj 3555 16 into into IN cord-005646-xhx9pzhj 3555 17 the the DT cord-005646-xhx9pzhj 3555 18 stomach stomach NN cord-005646-xhx9pzhj 3555 19 , , , cord-005646-xhx9pzhj 3555 20 mimicking mimic VBG cord-005646-xhx9pzhj 3555 21 e~)phageal e~)phageal JJ cord-005646-xhx9pzhj 3555 22 atresia.~se atresia.~se JJ cord-005646-xhx9pzhj 3555 23 1 1 CD cord-005646-xhx9pzhj 3555 24 : : : cord-005646-xhx9pzhj 3555 25 birth birth NN cord-005646-xhx9pzhj 3555 26 weight weight NN cord-005646-xhx9pzhj 3555 27 ( ( -LRB- cord-005646-xhx9pzhj 3555 28 BW BW NNP cord-005646-xhx9pzhj 3555 29 ) ) -RRB- cord-005646-xhx9pzhj 3556 1 185(I 185(i LS cord-005646-xhx9pzhj 3556 2 g g NN cord-005646-xhx9pzhj 3556 3 , , , cord-005646-xhx9pzhj 3556 4 gestational gestational JJ cord-005646-xhx9pzhj 3556 5 age age NN cord-005646-xhx9pzhj 3556 6 ( ( -LRB- cord-005646-xhx9pzhj 3556 7 GA GA NNP cord-005646-xhx9pzhj 3556 8 ) ) -RRB- cord-005646-xhx9pzhj 3556 9 37 37 CD cord-005646-xhx9pzhj 3556 10 wk wk NN cord-005646-xhx9pzhj 3556 11 , , , cord-005646-xhx9pzhj 3556 12 sepsis sepsis NN cord-005646-xhx9pzhj 3556 13 . . . cord-005646-xhx9pzhj 3557 1 Before before IN cord-005646-xhx9pzhj 3557 2 admission admission NN cord-005646-xhx9pzhj 3557 3 to to IN cord-005646-xhx9pzhj 3557 4 N1CU N1CU NNP cord-005646-xhx9pzhj 3557 5 , , , cord-005646-xhx9pzhj 3557 6 the the DT cord-005646-xhx9pzhj 3557 7 baby baby NN cord-005646-xhx9pzhj 3557 8 underwent undergo VBD cord-005646-xhx9pzhj 3557 9 multiple multiple JJ cord-005646-xhx9pzhj 3557 10 ET ET NNP cord-005646-xhx9pzhj 3557 11 inmbations inmbation NNS cord-005646-xhx9pzhj 3557 12 , , , cord-005646-xhx9pzhj 3557 13 because because IN cord-005646-xhx9pzhj 3557 14 of of IN cord-005646-xhx9pzhj 3557 15 inappropriate inappropriate JJ cord-005646-xhx9pzhj 3557 16 securing securing NN cord-005646-xhx9pzhj 3557 17 of of IN cord-005646-xhx9pzhj 3557 18 ET ET NNP cord-005646-xhx9pzhj 3557 19 robe robe NN cord-005646-xhx9pzhj 3557 20 . . . cord-005646-xhx9pzhj 3558 1 Bloody bloody JJ cord-005646-xhx9pzhj 3558 2 secretions secretion NNS cord-005646-xhx9pzhj 3558 3 in in IN cord-005646-xhx9pzhj 3558 4 pharynx pharynx NN cord-005646-xhx9pzhj 3558 5 were be VBD cord-005646-xhx9pzhj 3558 6 observed observe VBN cord-005646-xhx9pzhj 3558 7 . . . cord-005646-xhx9pzhj 3559 1 The the DT cord-005646-xhx9pzhj 3559 2 endoscopy endoscopy NN cord-005646-xhx9pzhj 3559 3 showed show VBD cord-005646-xhx9pzhj 3559 4 a a DT cord-005646-xhx9pzhj 3559 5 large large JJ cord-005646-xhx9pzhj 3559 6 lesion lesion NN cord-005646-xhx9pzhj 3559 7 at at IN cord-005646-xhx9pzhj 3559 8 the the DT cord-005646-xhx9pzhj 3559 9 end end NN cord-005646-xhx9pzhj 3559 10 of of IN cord-005646-xhx9pzhj 3559 11 proximal proximal JJ cord-005646-xhx9pzhj 3559 12 third third RB cord-005646-xhx9pzhj 3559 13 of of IN cord-005646-xhx9pzhj 3559 14 the the DT cord-005646-xhx9pzhj 3559 15 esophagus esophagus NN cord-005646-xhx9pzhj 3559 16 , , , cord-005646-xhx9pzhj 3559 17 Case case NN cord-005646-xhx9pzhj 3559 18 2 2 CD cord-005646-xhx9pzhj 3559 19 : : : cord-005646-xhx9pzhj 3559 20 BW BW NNP cord-005646-xhx9pzhj 3559 21 1080 1080 CD cord-005646-xhx9pzhj 3559 22 g g NNP cord-005646-xhx9pzhj 3559 23 , , , cord-005646-xhx9pzhj 3559 24 GA GA NNP cord-005646-xhx9pzhj 3559 25 32 32 CD cord-005646-xhx9pzhj 3559 26 wk wk NNS cord-005646-xhx9pzhj 3559 27 , , , cord-005646-xhx9pzhj 3559 28 RDS RDS NNP cord-005646-xhx9pzhj 3559 29 . . . cord-005646-xhx9pzhj 3560 1 Chest chest NN cord-005646-xhx9pzhj 3560 2 X x NN cord-005646-xhx9pzhj 3560 3 - - NN cord-005646-xhx9pzhj 3560 4 ray ray NN cord-005646-xhx9pzhj 3560 5 ( ( -LRB- cord-005646-xhx9pzhj 3560 6 CXR CXR NNP cord-005646-xhx9pzhj 3560 7 ) ) -RRB- cord-005646-xhx9pzhj 3560 8 showed show VBD cord-005646-xhx9pzhj 3560 9 a a DT cord-005646-xhx9pzhj 3560 10 retrostcrnal retrostcrnal JJ cord-005646-xhx9pzhj 3560 11 air air NN cord-005646-xhx9pzhj 3560 12 leak leak NN cord-005646-xhx9pzhj 3560 13 : : : cord-005646-xhx9pzhj 3560 14 the the DT cord-005646-xhx9pzhj 3560 15 NG NG NNP cord-005646-xhx9pzhj 3560 16 tube tube NN cord-005646-xhx9pzhj 3560 17 was be VBD cord-005646-xhx9pzhj 3560 18 stopped stop VBN cord-005646-xhx9pzhj 3560 19 } } -RRB- cord-005646-xhx9pzhj 3561 1 ~etwcen ~etwcen NFP cord-005646-xhx9pzhj 3561 2 D8 D8 NNP cord-005646-xhx9pzhj 3561 3 and and CC cord-005646-xhx9pzhj 3561 4 D9 D9 NNP cord-005646-xhx9pzhj 3561 5 and and CC cord-005646-xhx9pzhj 3561 6 soluble soluble JJ cord-005646-xhx9pzhj 3561 7 contrast contrast NN cord-005646-xhx9pzhj 3561 8 was be VBD cord-005646-xhx9pzhj 3561 9 seen see VBN cord-005646-xhx9pzhj 3561 10 in in IN cord-005646-xhx9pzhj 3561 11 upper upper JJ cord-005646-xhx9pzhj 3561 12 mediastinum mediastinum NNS cord-005646-xhx9pzhj 3561 13 . . . cord-005646-xhx9pzhj 3562 1 Case case NN cord-005646-xhx9pzhj 3562 2 3 3 CD cord-005646-xhx9pzhj 3562 3 : : : cord-005646-xhx9pzhj 3562 4 BW BW NNP cord-005646-xhx9pzhj 3562 5 76(/g 76(/g NNP cord-005646-xhx9pzhj 3562 6 , , , cord-005646-xhx9pzhj 3562 7 GA GA NNP cord-005646-xhx9pzhj 3562 8 26 26 CD cord-005646-xhx9pzhj 3562 9 wk wk NNS cord-005646-xhx9pzhj 3562 10 , , , cord-005646-xhx9pzhj 3562 11 RDS RDS NNP cord-005646-xhx9pzhj 3562 12 . . . cord-005646-xhx9pzhj 3563 1 The the DT cord-005646-xhx9pzhj 3563 2 endo endo NN cord-005646-xhx9pzhj 3563 3 ~ ~ NFP cord-005646-xhx9pzhj 3563 4 opy opy NN cord-005646-xhx9pzhj 3563 5 showed show VBD cord-005646-xhx9pzhj 3563 6 an an DT cord-005646-xhx9pzhj 3563 7 esophageal esophageal JJ cord-005646-xhx9pzhj 3563 8 lesion lesion NN cord-005646-xhx9pzhj 3563 9 . . . cord-005646-xhx9pzhj 3564 1 CXR CXR NNP cord-005646-xhx9pzhj 3564 2 showed show VBD cord-005646-xhx9pzhj 3564 3 a a DT cord-005646-xhx9pzhj 3564 4 paravertebral paravertebral JJ cord-005646-xhx9pzhj 3564 5 route route NN cord-005646-xhx9pzhj 3564 6 of of IN cord-005646-xhx9pzhj 3564 7 NG NG NNP cord-005646-xhx9pzhj 3564 8 tube tube NN cord-005646-xhx9pzhj 3564 9 and and CC cord-005646-xhx9pzhj 3564 10 a a DT cord-005646-xhx9pzhj 3564 11 right right JJ cord-005646-xhx9pzhj 3564 12 pneumothorax pneumothorax NN cord-005646-xhx9pzhj 3564 13 . . . cord-005646-xhx9pzhj 3565 1 Case case NN cord-005646-xhx9pzhj 3565 2 4 4 CD cord-005646-xhx9pzhj 3565 3 : : : cord-005646-xhx9pzhj 3565 4 BW BW NNP cord-005646-xhx9pzhj 3565 5 102(I 102(i CD cord-005646-xhx9pzhj 3565 6 g g NNP cord-005646-xhx9pzhj 3565 7 , , , cord-005646-xhx9pzhj 3565 8 CZ CZ NNP cord-005646-xhx9pzhj 3565 9 22 22 CD cord-005646-xhx9pzhj 3565 10 , , , cord-005646-xhx9pzhj 3565 11 .v .v NFP cord-005646-xhx9pzhj 3565 12 ! ! . cord-005646-xhx9pzhj 3565 13 : : : cord-005646-xhx9pzhj 3565 14 . . . cord-005646-xhx9pzhj 3566 1 RD RD NNP cord-005646-xhx9pzhj 3566 2 c. c. NNP cord-005646-xhx9pzhj 3566 3 ~ ~ NFP cord-005646-xhx9pzhj 3566 4 ! ! . cord-005646-xhx9pzhj 3566 5 , , , cord-005646-xhx9pzhj 3566 6 ' ' '' cord-005646-xhx9pzhj 3566 7 . . . cord-005646-xhx9pzhj 3567 1 : : : cord-005646-xhx9pzhj 3567 2 : : : cord-005646-xhx9pzhj 3567 3 ; ; : cord-005646-xhx9pzhj 3567 4 ; ; : cord-005646-xhx9pzhj 3567 5 : : : cord-005646-xhx9pzhj 3567 6 : : : cord-005646-xhx9pzhj 3567 7 : : : cord-005646-xhx9pzhj 3567 8 ' ' '' cord-005646-xhx9pzhj 3567 9 : : : cord-005646-xhx9pzhj 3567 10 ' ' '' cord-005646-xhx9pzhj 3567 11 _ _ NN cord-005646-xhx9pzhj 3567 12 ' ' '' cord-005646-xhx9pzhj 3567 13 rvt!~'2s rvt!~'2s UH cord-005646-xhx9pzhj 3567 14 L l NN cord-005646-xhx9pzhj 3567 15 " " '' cord-005646-xhx9pzhj 3567 16 ~k':.rvRx ~k':.rvRx NNP cord-005646-xhx9pzhj 3567 17 . . . cord-005646-xhx9pzhj 3568 1 cwr cwr NNP cord-005646-xhx9pzhj 3568 2 , , , cord-005646-xhx9pzhj 3568 3 d,,,,vs d,,,,vs XX cord-005646-xhx9pzhj 3569 1 ~,,mr ~,,mr NFP cord-005646-xhx9pzhj 3570 1 ~e ~e NNP cord-005646-xhx9pzhj 3570 2 , , , cord-005646-xhx9pzhj 3570 3 ~n ~n NNP cord-005646-xhx9pzhj 3570 4 rhe rhe JJ cord-005646-xhx9pzhj 3570 5 upper upper JJ cord-005646-xhx9pzhj 3570 6 mediastinum mediastinum NN cord-005646-xhx9pzhj 3570 7 and and CC cord-005646-xhx9pzhj 3570 8 abnormal abnormal JJ cord-005646-xhx9pzhj 3570 9 route route NN cord-005646-xhx9pzhj 3570 10 of of IN cord-005646-xhx9pzhj 3570 11 NG NG NNP cord-005646-xhx9pzhj 3570 12 tube tube NN cord-005646-xhx9pzhj 3570 13 through through IN cord-005646-xhx9pzhj 3570 14 a a DT cord-005646-xhx9pzhj 3570 15 false false JJ cord-005646-xhx9pzhj 3570 16 passage passage NN cord-005646-xhx9pzhj 3570 17 . . . cord-005646-xhx9pzhj 3571 1 Surgical surgical JJ cord-005646-xhx9pzhj 3571 2 intervention intervention NN cord-005646-xhx9pzhj 3571 3 is be VBZ cord-005646-xhx9pzhj 3571 4 needed need VBN cord-005646-xhx9pzhj 3571 5 in in IN cord-005646-xhx9pzhj 3571 6 case case NN cord-005646-xhx9pzhj 3571 7 of of IN cord-005646-xhx9pzhj 3571 8 mediastinitis mediastinitis NN cord-005646-xhx9pzhj 3571 9 or or CC cord-005646-xhx9pzhj 3571 10 mediastinal mediastinal JJ cord-005646-xhx9pzhj 3571 11 abscess abscess NN cord-005646-xhx9pzhj 3571 12 : : : cord-005646-xhx9pzhj 3571 13 conservative conservative JJ cord-005646-xhx9pzhj 3571 14 management management NN cord-005646-xhx9pzhj 3571 15 included include VBD cord-005646-xhx9pzhj 3571 16 broad broad JJ cord-005646-xhx9pzhj 3571 17 spectrum spectrum NN cord-005646-xhx9pzhj 3571 18 antibiotics antibiotic NNS cord-005646-xhx9pzhj 3571 19 , , , cord-005646-xhx9pzhj 3571 20 total total JJ cord-005646-xhx9pzhj 3571 21 parenteral parenteral JJ cord-005646-xhx9pzhj 3571 22 nutrition nutrition NN cord-005646-xhx9pzhj 3571 23 , , , cord-005646-xhx9pzhj 3571 24 antireflux antireflux NNP cord-005646-xhx9pzhj 3571 25 therapy therapy NN cord-005646-xhx9pzhj 3571 26 and and CC cord-005646-xhx9pzhj 3571 27 , , , cord-005646-xhx9pzhj 3571 28 if if IN cord-005646-xhx9pzhj 3571 29 necessary necessary JJ cord-005646-xhx9pzhj 3571 30 , , , cord-005646-xhx9pzhj 3571 31 drainage drainage NN cord-005646-xhx9pzhj 3571 32 of of IN cord-005646-xhx9pzhj 3571 33 air air NN cord-005646-xhx9pzhj 3571 34 leaks leak NNS cord-005646-xhx9pzhj 3571 35 . . . cord-005646-xhx9pzhj 3572 1 Enteral enteral NN cord-005646-xhx9pzhj 3572 2 feeding feeding NN cord-005646-xhx9pzhj 3572 3 has have VBZ cord-005646-xhx9pzhj 3572 4 been be VBN cord-005646-xhx9pzhj 3572 5 stopped stop VBN cord-005646-xhx9pzhj 3572 6 lor lor NNP cord-005646-xhx9pzhj 3572 7 15 15 CD cord-005646-xhx9pzhj 3572 8 days day NNS cord-005646-xhx9pzhj 3572 9 and and CC cord-005646-xhx9pzhj 3572 10 cautiously cautiously RB cord-005646-xhx9pzhj 3572 11 resumed resume VBD cord-005646-xhx9pzhj 3572 12 after after IN cord-005646-xhx9pzhj 3572 13 radiographic radiographic JJ cord-005646-xhx9pzhj 3572 14 study study NN cord-005646-xhx9pzhj 3572 15 . . . cord-005646-xhx9pzhj 3573 1 [ [ -LRB- cord-005646-xhx9pzhj 3573 2 x x SYM cord-005646-xhx9pzhj 3573 3 ~ ~ NFP cord-005646-xhx9pzhj 3573 4 cal cal NNP cord-005646-xhx9pzhj 3573 5 sequelae sequela NNS cord-005646-xhx9pzhj 3573 6 and and CC cord-005646-xhx9pzhj 3573 7 death death NN cord-005646-xhx9pzhj 3573 8 are be VBP cord-005646-xhx9pzhj 3573 9 uncommon uncommon JJ cord-005646-xhx9pzhj 3573 10 , , , cord-005646-xhx9pzhj 3573 11 but but CC cord-005646-xhx9pzhj 3573 12 IEP IEP NNP cord-005646-xhx9pzhj 3573 13 occur occur VBP cord-005646-xhx9pzhj 3573 14 in in IN cord-005646-xhx9pzhj 3573 15 newborns newborn NNS cord-005646-xhx9pzhj 3573 16 with with IN cord-005646-xhx9pzhj 3573 17 high high JJ cord-005646-xhx9pzhj 3573 18 risk risk NN cord-005646-xhx9pzhj 3573 19 of of IN cord-005646-xhx9pzhj 3573 20 death death NN cord-005646-xhx9pzhj 3573 21 due due IN cord-005646-xhx9pzhj 3573 22 to to IN cord-005646-xhx9pzhj 3573 23 prematurity prematurity NN cord-005646-xhx9pzhj 3573 24 and and CC cord-005646-xhx9pzhj 3573 25 other other JJ cord-005646-xhx9pzhj 3573 26 diseases disease NNS cord-005646-xhx9pzhj 3573 27 . . . cord-005646-xhx9pzhj 3574 1 In in IN cord-005646-xhx9pzhj 3574 2 our -PRON- PRP$ cord-005646-xhx9pzhj 3574 3 patients patient NNS cord-005646-xhx9pzhj 3574 4 , , , cord-005646-xhx9pzhj 3574 5 ET ET NNP cord-005646-xhx9pzhj 3574 6 intubation intubation NN cord-005646-xhx9pzhj 3574 7 has have VBZ cord-005646-xhx9pzhj 3574 8 been be VBN cord-005646-xhx9pzhj 3574 9 performed perform VBN cord-005646-xhx9pzhj 3574 10 by by IN cord-005646-xhx9pzhj 3574 11 experienced experienced JJ cord-005646-xhx9pzhj 3574 12 personnel personnel NNS cord-005646-xhx9pzhj 3574 13 : : : cord-005646-xhx9pzhj 3574 14 therefore therefore RB cord-005646-xhx9pzhj 3574 15 the the DT cord-005646-xhx9pzhj 3574 16 lack lack NN cord-005646-xhx9pzhj 3574 17 of of IN cord-005646-xhx9pzhj 3574 18 skills skill NNS cord-005646-xhx9pzhj 3574 19 in in IN cord-005646-xhx9pzhj 3574 20 resu resu NN cord-005646-xhx9pzhj 3574 21 ~ ~ NFP cord-005646-xhx9pzhj 3574 22 itative itative NNP cord-005646-xhx9pzhj 3574 23 procedures procedure NNS cord-005646-xhx9pzhj 3574 24 is be VBZ cord-005646-xhx9pzhj 3574 25 not not RB cord-005646-xhx9pzhj 3574 26 always always RB cord-005646-xhx9pzhj 3574 27 the the DT cord-005646-xhx9pzhj 3574 28 main main JJ cord-005646-xhx9pzhj 3574 29 factor factor NN cord-005646-xhx9pzhj 3574 30 of of IN cord-005646-xhx9pzhj 3574 31 IEP IEP NNP cord-005646-xhx9pzhj 3574 32 . . . cord-005646-xhx9pzhj 3575 1 Prevention Prevention NNP cord-005646-xhx9pzhj 3575 2 of of IN cord-005646-xhx9pzhj 3575 3 IEP IEP NNP cord-005646-xhx9pzhj 3575 4 requires require VBZ cord-005646-xhx9pzhj 3575 5 appropriate appropriate JJ cord-005646-xhx9pzhj 3575 6 materials material NNS cord-005646-xhx9pzhj 3575 7 ( ( -LRB- cord-005646-xhx9pzhj 3575 8 ET ET NNP cord-005646-xhx9pzhj 3575 9 tubes tube NNS cord-005646-xhx9pzhj 3575 10 , , , cord-005646-xhx9pzhj 3575 11 laryngoscope laryngoscope NN cord-005646-xhx9pzhj 3575 12 blades blade NNS cord-005646-xhx9pzhj 3575 13 , , , cord-005646-xhx9pzhj 3575 14 suction suction NN cord-005646-xhx9pzhj 3575 15 catheters catheter NNS cord-005646-xhx9pzhj 3575 16 ) ) -RRB- cord-005646-xhx9pzhj 3575 17 , , , cord-005646-xhx9pzhj 3575 18 and and CC cord-005646-xhx9pzhj 3575 19 procedures procedure NNS cord-005646-xhx9pzhj 3575 20 ( ( -LRB- cord-005646-xhx9pzhj 3575 21 positioning positioning NN cord-005646-xhx9pzhj 3575 22 of of IN cord-005646-xhx9pzhj 3575 23 the the DT cord-005646-xhx9pzhj 3575 24 infant infant NN cord-005646-xhx9pzhj 3575 25 with with IN cord-005646-xhx9pzhj 3575 26 correct correct JJ cord-005646-xhx9pzhj 3575 27 neck neck NN cord-005646-xhx9pzhj 3575 28 estension estension NN cord-005646-xhx9pzhj 3575 29 , , , cord-005646-xhx9pzhj 3575 30 firm firm NN cord-005646-xhx9pzhj 3575 31 ET ET NNP cord-005646-xhx9pzhj 3575 32 placement placement NN cord-005646-xhx9pzhj 3575 33 ) ) -RRB- cord-005646-xhx9pzhj 3575 34 . . . cord-005646-xhx9pzhj 3576 1 Sedation sedation NN cord-005646-xhx9pzhj 3576 2 and and CC cord-005646-xhx9pzhj 3576 3 pain pain NN cord-005646-xhx9pzhj 3576 4 control control NN cord-005646-xhx9pzhj 3576 5 may may MD cord-005646-xhx9pzhj 3576 6 help help VB cord-005646-xhx9pzhj 3576 7 to to TO cord-005646-xhx9pzhj 3576 8 prevent prevent VB cord-005646-xhx9pzhj 3576 9 the the DT cord-005646-xhx9pzhj 3576 10 muscle muscle NN cord-005646-xhx9pzhj 3576 11 spasm spasm NN cord-005646-xhx9pzhj 3576 12 . . . cord-005646-xhx9pzhj 3577 1 Aggressive aggressive JJ cord-005646-xhx9pzhj 3577 2 treatment treatment NN cord-005646-xhx9pzhj 3577 3 has have VBZ cord-005646-xhx9pzhj 3577 4 improved improve VBN cord-005646-xhx9pzhj 3577 5 the the DT cord-005646-xhx9pzhj 3577 6 tong tong NNP cord-005646-xhx9pzhj 3577 7 - - HYPH cord-005646-xhx9pzhj 3577 8 term term NN cord-005646-xhx9pzhj 3577 9 outcome outcome NN cord-005646-xhx9pzhj 3577 10 of of IN cord-005646-xhx9pzhj 3577 11 extremely extremely RB cord-005646-xhx9pzhj 3577 12 low low JJ cord-005646-xhx9pzhj 3577 13 birth birth NN cord-005646-xhx9pzhj 3577 14 weight weight NN cord-005646-xhx9pzhj 3577 15 neonates neonate NNS cord-005646-xhx9pzhj 3577 16 ( ( -LRB- cord-005646-xhx9pzhj 3577 17 ELBW ELBW NNP cord-005646-xhx9pzhj 3577 18 ) ) -RRB- cord-005646-xhx9pzhj 3577 19 but but CC cord-005646-xhx9pzhj 3577 20 it -PRON- PRP cord-005646-xhx9pzhj 3577 21 has have VBZ cord-005646-xhx9pzhj 3577 22 also also RB cord-005646-xhx9pzhj 3577 23 increased increase VBN cord-005646-xhx9pzhj 3577 24 the the DT cord-005646-xhx9pzhj 3577 25 chances chance NNS cord-005646-xhx9pzhj 3577 26 of of IN cord-005646-xhx9pzhj 3577 27 iatrogenic iatrogenic JJ cord-005646-xhx9pzhj 3577 28 lesions lesion NNS cord-005646-xhx9pzhj 3577 29 . . . cord-005646-xhx9pzhj 3578 1 Reviewing review VBG cord-005646-xhx9pzhj 3578 2 the the DT cord-005646-xhx9pzhj 3578 3 charts chart NNS cord-005646-xhx9pzhj 3578 4 of of IN cord-005646-xhx9pzhj 3578 5 our -PRON- PRP$ cord-005646-xhx9pzhj 3578 6 neonates neonate NNS cord-005646-xhx9pzhj 3578 7 we -PRON- PRP cord-005646-xhx9pzhj 3578 8 observed observe VBD cord-005646-xhx9pzhj 3578 9 a a DT cord-005646-xhx9pzhj 3578 10 high high JJ cord-005646-xhx9pzhj 3578 11 number number NN cord-005646-xhx9pzhj 3578 12 of of IN cord-005646-xhx9pzhj 3578 13 vascular vascular JJ cord-005646-xhx9pzhj 3578 14 injuries injury NNS cord-005646-xhx9pzhj 3578 15 . . . cord-005646-xhx9pzhj 3579 1 From from IN cord-005646-xhx9pzhj 3579 2 1987 1987 CD cord-005646-xhx9pzhj 3579 3 to to IN cord-005646-xhx9pzhj 3579 4 1994 1994 CD cord-005646-xhx9pzhj 3579 5 , , , cord-005646-xhx9pzhj 3579 6 2898 2898 CD cord-005646-xhx9pzhj 3579 7 neonates neonate NNS cord-005646-xhx9pzhj 3579 8 were be VBD cord-005646-xhx9pzhj 3579 9 admitted admit VBN cord-005646-xhx9pzhj 3579 10 to to IN cord-005646-xhx9pzhj 3579 11 the the DT cord-005646-xhx9pzhj 3579 12 neonatal neonatal JJ cord-005646-xhx9pzhj 3579 13 intensive intensive JJ cord-005646-xhx9pzhj 3579 14 care care NN cord-005646-xhx9pzhj 3579 15 unit unit NN cord-005646-xhx9pzhj 3579 16 ( ( -LRB- cord-005646-xhx9pzhj 3579 17 NICU NICU NNP cord-005646-xhx9pzhj 3579 18 ) ) -RRB- cord-005646-xhx9pzhj 3579 19 ; ; : cord-005646-xhx9pzhj 3579 20 335 335 CD cord-005646-xhx9pzhj 3579 21 of of IN cord-005646-xhx9pzhj 3579 22 them -PRON- PRP cord-005646-xhx9pzhj 3579 23 were be VBD cord-005646-xhx9pzhj 3579 24 ELBW ELBW NNP cord-005646-xhx9pzhj 3579 25 ( ( -LRB- cord-005646-xhx9pzhj 3579 26 11.5 11.5 CD cord-005646-xhx9pzhj 3579 27 % % NN cord-005646-xhx9pzhj 3579 28 ) ) -RRB- cord-005646-xhx9pzhj 3579 29 . . . cord-005646-xhx9pzhj 3580 1 Studying study VBG cord-005646-xhx9pzhj 3580 2 the the DT cord-005646-xhx9pzhj 3580 3 charts chart NNS cord-005646-xhx9pzhj 3580 4 of of IN cord-005646-xhx9pzhj 3580 5 these these DT cord-005646-xhx9pzhj 3580 6 ELBW ELBW NNP cord-005646-xhx9pzhj 3580 7 we -PRON- PRP cord-005646-xhx9pzhj 3580 8 observed observe VBD cord-005646-xhx9pzhj 3580 9 9 9 CD cord-005646-xhx9pzhj 3580 10 cases case NNS cord-005646-xhx9pzhj 3580 11 ( ( -LRB- cord-005646-xhx9pzhj 3580 12 4 4 CD cord-005646-xhx9pzhj 3580 13 M M NNP cord-005646-xhx9pzhj 3580 14 -5 -5 NNP cord-005646-xhx9pzhj 3580 15 F F NNP cord-005646-xhx9pzhj 3580 16 ) ) -RRB- cord-005646-xhx9pzhj 3580 17 with with IN cord-005646-xhx9pzhj 3580 18 vascular vascular JJ cord-005646-xhx9pzhj 3580 19 lesions lesion NNS cord-005646-xhx9pzhj 3580 20 ( ( -LRB- cord-005646-xhx9pzhj 3580 21 2.6 2.6 CD cord-005646-xhx9pzhj 3580 22 % % NN cord-005646-xhx9pzhj 3580 23 ) ) -RRB- cord-005646-xhx9pzhj 3580 24 . . . cord-005646-xhx9pzhj 3581 1 Mean mean JJ cord-005646-xhx9pzhj 3581 2 gestational gestational JJ cord-005646-xhx9pzhj 3581 3 age age NN cord-005646-xhx9pzhj 3581 4 of of IN cord-005646-xhx9pzhj 3581 5 these these DT cord-005646-xhx9pzhj 3581 6 patients patient NNS cord-005646-xhx9pzhj 3581 7 was be VBD cord-005646-xhx9pzhj 3581 8 28.7 28.7 CD cord-005646-xhx9pzhj 3581 9 weeks week NNS cord-005646-xhx9pzhj 3581 10 ( ( -LRB- cord-005646-xhx9pzhj 3581 11 rain rain NN cord-005646-xhx9pzhj 3581 12 24-max33 24-max33 CD cord-005646-xhx9pzhj 3581 13 ) ) -RRB- cord-005646-xhx9pzhj 3581 14 . . . cord-005646-xhx9pzhj 3582 1 Mean mean JJ cord-005646-xhx9pzhj 3582 2 weight weight NN cord-005646-xhx9pzhj 3582 3 at at IN cord-005646-xhx9pzhj 3582 4 birth birth NN cord-005646-xhx9pzhj 3582 5 was be VBD cord-005646-xhx9pzhj 3582 6 880 880 CD cord-005646-xhx9pzhj 3582 7 g g NN cord-005646-xhx9pzhj 3582 8 . . . cord-005646-xhx9pzhj 3583 1 Mean mean JJ cord-005646-xhx9pzhj 3583 2 weight weight NN cord-005646-xhx9pzhj 3583 3 at at IN cord-005646-xhx9pzhj 3583 4 diagnosis diagnosis NN cord-005646-xhx9pzhj 3583 5 was be VBD cord-005646-xhx9pzhj 3583 6 1825 1825 CD cord-005646-xhx9pzhj 3583 7 g g NN cord-005646-xhx9pzhj 3583 8 ( ( -LRB- cord-005646-xhx9pzhj 3583 9 1230 1230 CD cord-005646-xhx9pzhj 3583 10 - - SYM cord-005646-xhx9pzhj 3583 11 2700 2700 CD cord-005646-xhx9pzhj 3583 12 ) ) -RRB- cord-005646-xhx9pzhj 3583 13 . . . cord-005646-xhx9pzhj 3584 1 In in IN cord-005646-xhx9pzhj 3584 2 the the DT cord-005646-xhx9pzhj 3584 3 same same JJ cord-005646-xhx9pzhj 3584 4 period period NN cord-005646-xhx9pzhj 3584 5 10 10 CD cord-005646-xhx9pzhj 3584 6 patients patient NNS cord-005646-xhx9pzhj 3584 7 with with IN cord-005646-xhx9pzhj 3584 8 vascular vascular JJ cord-005646-xhx9pzhj 3584 9 injuries injury NNS cord-005646-xhx9pzhj 3584 10 were be VBD cord-005646-xhx9pzhj 3584 11 reported report VBN cord-005646-xhx9pzhj 3584 12 in in IN cord-005646-xhx9pzhj 3584 13 the the DT cord-005646-xhx9pzhj 3584 14 2563 2563 CD cord-005646-xhx9pzhj 3584 15 neonates neonate NNS cord-005646-xhx9pzhj 3584 16 over over IN cord-005646-xhx9pzhj 3584 17 1500 1500 CD cord-005646-xhx9pzhj 3584 18 g g NN cord-005646-xhx9pzhj 3584 19 ( ( -LRB- cord-005646-xhx9pzhj 3584 20 0.3 0.3 CD cord-005646-xhx9pzhj 3584 21 % % NN cord-005646-xhx9pzhj 3584 22 ) ) -RRB- cord-005646-xhx9pzhj 3584 23 . . . cord-005646-xhx9pzhj 3585 1 The the DT cord-005646-xhx9pzhj 3585 2 injuries injury NNS cord-005646-xhx9pzhj 3585 3 observed observe VBN cord-005646-xhx9pzhj 3585 4 in in IN cord-005646-xhx9pzhj 3585 5 ELBW ELBW NNP cord-005646-xhx9pzhj 3585 6 group group NN cord-005646-xhx9pzhj 3585 7 were be VBD cord-005646-xhx9pzhj 3585 8 : : : cord-005646-xhx9pzhj 3585 9 6 6 CD cord-005646-xhx9pzhj 3585 10 arteriovenous arteriovenous JJ cord-005646-xhx9pzhj 3585 11 fistula fistula NN cord-005646-xhx9pzhj 3585 12 ( ( -LRB- cord-005646-xhx9pzhj 3585 13 2 2 CD cord-005646-xhx9pzhj 3585 14 bilateral bilateral JJ cord-005646-xhx9pzhj 3585 15 ) ) -RRB- cord-005646-xhx9pzhj 3585 16 at at IN cord-005646-xhx9pzhj 3585 17 femoral femoral JJ cord-005646-xhx9pzhj 3585 18 , , , cord-005646-xhx9pzhj 3585 19 level level NN cord-005646-xhx9pzhj 3585 20 , , , cord-005646-xhx9pzhj 3585 21 1 1 CD cord-005646-xhx9pzhj 3585 22 carotid carotid NN cord-005646-xhx9pzhj 3585 23 lesion lesion NN cord-005646-xhx9pzhj 3585 24 and and CC cord-005646-xhx9pzhj 3585 25 2 2 CD cord-005646-xhx9pzhj 3585 26 limb limb NN cord-005646-xhx9pzhj 3585 27 ischemic ischemic JJ cord-005646-xhx9pzhj 3585 28 lesions lesion NNS cord-005646-xhx9pzhj 3585 29 . . . cord-005646-xhx9pzhj 3586 1 Aetiology Aetiology NNP cord-005646-xhx9pzhj 3586 2 was be VBD cord-005646-xhx9pzhj 3586 3 in in IN cord-005646-xhx9pzhj 3586 4 7 7 CD cord-005646-xhx9pzhj 3586 5 cases case NNS cord-005646-xhx9pzhj 3586 6 by by IN cord-005646-xhx9pzhj 3586 7 venipuncture venipuncture NN cord-005646-xhx9pzhj 3586 8 , , , cord-005646-xhx9pzhj 3586 9 in in IN cord-005646-xhx9pzhj 3586 10 one one CD cord-005646-xhx9pzhj 3586 11 case case NN cord-005646-xhx9pzhj 3586 12 umbilical umbilical JJ cord-005646-xhx9pzhj 3586 13 catheter catheter NN cord-005646-xhx9pzhj 3586 14 and and CC cord-005646-xhx9pzhj 3586 15 in in IN cord-005646-xhx9pzhj 3586 16 the the DT cord-005646-xhx9pzhj 3586 17 case case NN cord-005646-xhx9pzhj 3586 18 of of IN cord-005646-xhx9pzhj 3586 19 carotid carotid JJ cord-005646-xhx9pzhj 3586 20 lesion lesion NN cord-005646-xhx9pzhj 3586 21 a a DT cord-005646-xhx9pzhj 3586 22 wrong wrong JJ cord-005646-xhx9pzhj 3586 23 surgical surgical JJ cord-005646-xhx9pzhj 3586 24 maneuver maneuver NN cord-005646-xhx9pzhj 3586 25 . . . cord-005646-xhx9pzhj 3587 1 No no DT cord-005646-xhx9pzhj 3587 2 general general JJ cord-005646-xhx9pzhj 3587 3 simptoms simptom NNS cord-005646-xhx9pzhj 3587 4 were be VBD cord-005646-xhx9pzhj 3587 5 observed observe VBN cord-005646-xhx9pzhj 3587 6 . . . cord-005646-xhx9pzhj 3588 1 The the DT cord-005646-xhx9pzhj 3588 2 vessels vessel NNS cord-005646-xhx9pzhj 3588 3 were be VBD cord-005646-xhx9pzhj 3588 4 repaired repair VBN cord-005646-xhx9pzhj 3588 5 with with IN cord-005646-xhx9pzhj 3588 6 microsurgical microsurgical JJ cord-005646-xhx9pzhj 3588 7 technique technique NN cord-005646-xhx9pzhj 3588 8 in in IN cord-005646-xhx9pzhj 3588 9 six six CD cord-005646-xhx9pzhj 3588 10 cases case NNS cord-005646-xhx9pzhj 3588 11 : : : cord-005646-xhx9pzhj 3588 12 the the DT cord-005646-xhx9pzhj 3588 13 carotid carotid JJ cord-005646-xhx9pzhj 3588 14 lesion lesion NN cord-005646-xhx9pzhj 3588 15 and and CC cord-005646-xhx9pzhj 3588 16 five five CD cord-005646-xhx9pzhj 3588 17 arteriovenous arteriovenous JJ cord-005646-xhx9pzhj 3588 18 fistula fistula NN cord-005646-xhx9pzhj 3588 19 ; ; : cord-005646-xhx9pzhj 3588 20 one one CD cord-005646-xhx9pzhj 3588 21 case case NN cord-005646-xhx9pzhj 3588 22 was be VBD cord-005646-xhx9pzhj 3588 23 solved solve VBN cord-005646-xhx9pzhj 3588 24 with with IN cord-005646-xhx9pzhj 3588 25 thrombolitic thrombolitic JJ cord-005646-xhx9pzhj 3588 26 drugs drug NNS cord-005646-xhx9pzhj 3588 27 ; ; : cord-005646-xhx9pzhj 3588 28 an an DT cord-005646-xhx9pzhj 3588 29 amputation amputation NN cord-005646-xhx9pzhj 3588 30 at at IN cord-005646-xhx9pzhj 3588 31 knee knee NN cord-005646-xhx9pzhj 3588 32 level level NN cord-005646-xhx9pzhj 3588 33 was be VBD cord-005646-xhx9pzhj 3588 34 required require VBN cord-005646-xhx9pzhj 3588 35 in in IN cord-005646-xhx9pzhj 3588 36 one one CD cord-005646-xhx9pzhj 3588 37 case case NN cord-005646-xhx9pzhj 3588 38 after after IN cord-005646-xhx9pzhj 3588 39 a a DT cord-005646-xhx9pzhj 3588 40 long long JJ cord-005646-xhx9pzhj 3588 41 period period NN cord-005646-xhx9pzhj 3588 42 of of IN cord-005646-xhx9pzhj 3588 43 medical medical JJ cord-005646-xhx9pzhj 3588 44 treatment treatment NN cord-005646-xhx9pzhj 3588 45 . . . cord-005646-xhx9pzhj 3589 1 The the DT cord-005646-xhx9pzhj 3589 2 last last JJ cord-005646-xhx9pzhj 3589 3 neonate neonate NN cord-005646-xhx9pzhj 3589 4 with with IN cord-005646-xhx9pzhj 3589 5 an an DT cord-005646-xhx9pzhj 3589 6 arteriovenous arteriovenous JJ cord-005646-xhx9pzhj 3589 7 fistula fistula NN cord-005646-xhx9pzhj 3589 8 was be VBD cord-005646-xhx9pzhj 3589 9 only only RB cord-005646-xhx9pzhj 3589 10 observed observe VBN cord-005646-xhx9pzhj 3589 11 for for IN cord-005646-xhx9pzhj 3589 12 parent parent NN cord-005646-xhx9pzhj 3589 13 's 's POS cord-005646-xhx9pzhj 3589 14 will will NN cord-005646-xhx9pzhj 3589 15 . . . cord-005646-xhx9pzhj 3590 1 At at IN cord-005646-xhx9pzhj 3590 2 follow follow NN cord-005646-xhx9pzhj 3590 3 - - HYPH cord-005646-xhx9pzhj 3590 4 up up NN cord-005646-xhx9pzhj 3590 5 ( ( -LRB- cord-005646-xhx9pzhj 3590 6 clinical clinical JJ cord-005646-xhx9pzhj 3590 7 and and CC cord-005646-xhx9pzhj 3590 8 by by IN cord-005646-xhx9pzhj 3590 9 ecodoppler ecodoppler NNP cord-005646-xhx9pzhj 3590 10 ) ) -RRB- cord-005646-xhx9pzhj 3590 11 7 7 CD cord-005646-xhx9pzhj 3590 12 out out IN cord-005646-xhx9pzhj 3590 13 of of IN cord-005646-xhx9pzhj 3590 14 9 9 CD cord-005646-xhx9pzhj 3590 15 neonates neonate NNS cord-005646-xhx9pzhj 3590 16 presented present VBD cord-005646-xhx9pzhj 3590 17 normal normal JJ cord-005646-xhx9pzhj 3590 18 vascular vascular JJ cord-005646-xhx9pzhj 3590 19 function function NN cord-005646-xhx9pzhj 3590 20 without without IN cord-005646-xhx9pzhj 3590 21 sequelae sequela NNS cord-005646-xhx9pzhj 3590 22 . . . cord-005646-xhx9pzhj 3591 1 From from IN cord-005646-xhx9pzhj 3591 2 our -PRON- PRP$ cord-005646-xhx9pzhj 3591 3 experience experience NN cord-005646-xhx9pzhj 3591 4 ELBW ELBW NNP cord-005646-xhx9pzhj 3591 5 neonates neonate NNS cord-005646-xhx9pzhj 3591 6 have have VBP cord-005646-xhx9pzhj 3591 7 more more JJR cord-005646-xhx9pzhj 3591 8 chances chance NNS cord-005646-xhx9pzhj 3591 9 than than IN cord-005646-xhx9pzhj 3591 10 older old JJR cord-005646-xhx9pzhj 3591 11 neonates neonate NNS cord-005646-xhx9pzhj 3591 12 to to TO cord-005646-xhx9pzhj 3591 13 develop develop VB cord-005646-xhx9pzhj 3591 14 iatrogenic iatrogenic JJ cord-005646-xhx9pzhj 3591 15 vascular vascular JJ cord-005646-xhx9pzhj 3591 16 lesions lesion NNS cord-005646-xhx9pzhj 3591 17 . . . cord-005646-xhx9pzhj 3592 1 We -PRON- PRP cord-005646-xhx9pzhj 3592 2 advocate advocate VBP cord-005646-xhx9pzhj 3592 3 an an DT cord-005646-xhx9pzhj 3592 4 aggressive aggressive JJ cord-005646-xhx9pzhj 3592 5 microsurgery microsurgery NN cord-005646-xhx9pzhj 3592 6 and/or and/or CC cord-005646-xhx9pzhj 3592 7 medical medical JJ cord-005646-xhx9pzhj 3592 8 treatment treatment NN cord-005646-xhx9pzhj 3592 9 to to TO cord-005646-xhx9pzhj 3592 10 obtain obtain VB cord-005646-xhx9pzhj 3592 11 good good JJ cord-005646-xhx9pzhj 3592 12 results result NNS cord-005646-xhx9pzhj 3592 13 and and CC cord-005646-xhx9pzhj 3592 14 prevent prevent VBP cord-005646-xhx9pzhj 3592 15 late late JJ cord-005646-xhx9pzhj 3592 16 sequelae sequela NNS cord-005646-xhx9pzhj 3592 17 . . . cord-005646-xhx9pzhj 3593 1 A a DT cord-005646-xhx9pzhj 3593 2 RETROSPECTIVE retrospective JJ cord-005646-xhx9pzhj 3593 3 COMPARISON comparison NN cord-005646-xhx9pzhj 3593 4 BETWEEN between IN cord-005646-xhx9pzhj 3593 5 2 2 CD cord-005646-xhx9pzhj 3593 6 NATURAL natural JJ cord-005646-xhx9pzhj 3593 7 SURFACTANTS surfactant NNS cord-005646-xhx9pzhj 3593 8 L.J.I.ZimmermanG L.J.I.ZimmermanG NNP cord-005646-xhx9pzhj 3593 9 M.C.M M.C.M NNP cord-005646-xhx9pzhj 3593 10 , , , cord-005646-xhx9pzhj 3593 11 van van NNP cord-005646-xhx9pzhj 3593 12 Oosten Oosten NNP cord-005646-xhx9pzhj 3593 13 . . . cord-005646-xhx9pzhj 3594 1 Dept Dept NNP cord-005646-xhx9pzhj 3594 2 . . . cord-005646-xhx9pzhj 3594 3 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 3594 4 , , , cord-005646-xhx9pzhj 3594 5 Div Div NNP cord-005646-xhx9pzhj 3594 6 . . . cord-005646-xhx9pzhj 3595 1 Neonatofogy Neonatofogy NNP cord-005646-xhx9pzhj 3595 2 , , , cord-005646-xhx9pzhj 3595 3 Sophia Sophia NNP cord-005646-xhx9pzhj 3595 4 Children Children NNP cord-005646-xhx9pzhj 3595 5 's 's POS cord-005646-xhx9pzhj 3595 6 Hospital Hospital NNP cord-005646-xhx9pzhj 3595 7 / / SYM cord-005646-xhx9pzhj 3595 8 Erasmus Erasmus NNP cord-005646-xhx9pzhj 3595 9 University University NNP cord-005646-xhx9pzhj 3595 10 , , , cord-005646-xhx9pzhj 3595 11 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 3595 12 , , , cord-005646-xhx9pzhj 3595 13 The the DT cord-005646-xhx9pzhj 3595 14 Netherlands Netherlands NNP cord-005646-xhx9pzhj 3595 15 . . . cord-005646-xhx9pzhj 3596 1 Aim aim VB cord-005646-xhx9pzhj 3596 2 : : : cord-005646-xhx9pzhj 3596 3 Retrospective retrospective JJ cord-005646-xhx9pzhj 3596 4 comparison comparison NN cord-005646-xhx9pzhj 3596 5 of of IN cord-005646-xhx9pzhj 3596 6 Alvofact Alvofact NNP cord-005646-xhx9pzhj 3596 7 ( ( -LRB- cord-005646-xhx9pzhj 3596 8 in in IN cord-005646-xhx9pzhj 3596 9 1993 1993 CD cord-005646-xhx9pzhj 3596 10 ) ) -RRB- cord-005646-xhx9pzhj 3596 11 versus versus IN cord-005646-xhx9pzhj 3596 12 Survanta Survanta NNP cord-005646-xhx9pzhj 3596 13 ( ( -LRB- cord-005646-xhx9pzhj 3596 14 in in IN cord-005646-xhx9pzhj 3596 15 1994 1994 CD cord-005646-xhx9pzhj 3596 16 ) ) -RRB- cord-005646-xhx9pzhj 3596 17 as as IN cord-005646-xhx9pzhj 3596 18 rescue rescue NN cord-005646-xhx9pzhj 3596 19 treatment treatment NN cord-005646-xhx9pzhj 3596 20 for for IN cord-005646-xhx9pzhj 3596 21 neonatal neonatal JJ cord-005646-xhx9pzhj 3596 22 respiratory respiratory JJ cord-005646-xhx9pzhj 3596 23 distress distress NN cord-005646-xhx9pzhj 3596 24 syndrome syndrome NN cord-005646-xhx9pzhj 3596 25 ( ( -LRB- cord-005646-xhx9pzhj 3596 26 RDS RDS NNP cord-005646-xhx9pzhj 3596 27 ) ) -RRB- cord-005646-xhx9pzhj 3596 28 . . . cord-005646-xhx9pzhj 3597 1 Methods method NNS cord-005646-xhx9pzhj 3597 2 : : : cord-005646-xhx9pzhj 3598 1 Both both DT cord-005646-xhx9pzhj 3598 2 surfactants surfactant NNS cord-005646-xhx9pzhj 3598 3 were be VBD cord-005646-xhx9pzhj 3598 4 given give VBN cord-005646-xhx9pzhj 3598 5 at at IN cord-005646-xhx9pzhj 3598 6 an an DT cord-005646-xhx9pzhj 3598 7 initial initial JJ cord-005646-xhx9pzhj 3598 8 dose dose NN cord-005646-xhx9pzhj 3598 9 of of IN cord-005646-xhx9pzhj 3598 10 100 100 CD cord-005646-xhx9pzhj 3598 11 mg mg NNP cord-005646-xhx9pzhj 3598 12 / / SYM cord-005646-xhx9pzhj 3598 13 kg kg NNP cord-005646-xhx9pzhj 3598 14 ( ( -LRB- cord-005646-xhx9pzhj 3598 15 except except IN cord-005646-xhx9pzhj 3598 16 for for IN cord-005646-xhx9pzhj 3598 17 Alvofact Alvofact NNP cord-005646-xhx9pzhj 3598 18 50 50 CD cord-005646-xhx9pzhj 3598 19 mg mg NNP cord-005646-xhx9pzhj 3598 20 / / SYM cord-005646-xhx9pzhj 3598 21 kg kg NNS cord-005646-xhx9pzhj 3598 22 for for IN cord-005646-xhx9pzhj 3598 23 mild mild JJ cord-005646-xhx9pzhj 3598 24 RDS RDS NNP cord-005646-xhx9pzhj 3598 25 grade grade NN cord-005646-xhx9pzhj 3598 26 MI MI NNP cord-005646-xhx9pzhj 3598 27 ) ) -RRB- cord-005646-xhx9pzhj 3598 28 . . . cord-005646-xhx9pzhj 3599 1 Repeat repeat NN cord-005646-xhx9pzhj 3599 2 doses dose NNS cord-005646-xhx9pzhj 3599 3 were be VBD cord-005646-xhx9pzhj 3599 4 attowed attowe VBN cord-005646-xhx9pzhj 3599 5 ( ( -LRB- cord-005646-xhx9pzhj 3599 6 Survanta Survanta NNP cord-005646-xhx9pzhj 3599 7 100 100 CD cord-005646-xhx9pzhj 3599 8 mg mg NNP cord-005646-xhx9pzhj 3599 9 / / SYM cord-005646-xhx9pzhj 3599 10 kg kg NNP cord-005646-xhx9pzhj 3599 11 , , , cord-005646-xhx9pzhj 3600 1 Alvofact Alvofact NNP cord-005646-xhx9pzhj 3600 2 50 50 CD cord-005646-xhx9pzhj 3600 3 mg mg NNP cord-005646-xhx9pzhj 3600 4 / / SYM cord-005646-xhx9pzhj 3600 5 kg kg NNP cord-005646-xhx9pzhj 3600 6 ) ) -RRB- cord-005646-xhx9pzhj 3600 7 up up IN cord-005646-xhx9pzhj 3600 8 to to IN cord-005646-xhx9pzhj 3600 9 a a DT cord-005646-xhx9pzhj 3600 10 maximum maximum NN cord-005646-xhx9pzhj 3600 11 of of IN cord-005646-xhx9pzhj 3600 12 200 200 CD cord-005646-xhx9pzhj 3600 13 mg mg NNP cord-005646-xhx9pzhj 3600 14 / / SYM cord-005646-xhx9pzhj 3600 15 kg kg NNS cord-005646-xhx9pzhj 3600 16 , , , cord-005646-xhx9pzhj 3600 17 All all DT cord-005646-xhx9pzhj 3600 18 parameters parameter NNS cord-005646-xhx9pzhj 3600 19 and and CC cord-005646-xhx9pzhj 3600 20 outcome outcome NN cord-005646-xhx9pzhj 3600 21 criteria criterion NNS cord-005646-xhx9pzhj 3600 22 were be VBD cord-005646-xhx9pzhj 3600 23 strictly strictly RB cord-005646-xhx9pzhj 3600 24 defined define VBN cord-005646-xhx9pzhj 3600 25 beforehand beforehand RB cord-005646-xhx9pzhj 3600 26 . . . cord-005646-xhx9pzhj 3601 1 The the DT cord-005646-xhx9pzhj 3601 2 initial initial JJ cord-005646-xhx9pzhj 3601 3 response response NN cord-005646-xhx9pzhj 3601 4 ( ( -LRB- cord-005646-xhx9pzhj 3601 5 good good JJ cord-005646-xhx9pzhj 3601 6 , , , cord-005646-xhx9pzhj 3601 7 mild mild JJ cord-005646-xhx9pzhj 3601 8 , , , cord-005646-xhx9pzhj 3601 9 no no DT cord-005646-xhx9pzhj 3601 10 response response NN cord-005646-xhx9pzhj 3601 11 , , , cord-005646-xhx9pzhj 3601 12 relapse relapse NN cord-005646-xhx9pzhj 3601 13 ) ) -RRB- cord-005646-xhx9pzhj 3601 14 to to IN cord-005646-xhx9pzhj 3601 15 surfactam surfactam NNP cord-005646-xhx9pzhj 3601 16 therapy therapy NNP cord-005646-xhx9pzhj 3601 17 was be VBD cord-005646-xhx9pzhj 3601 18 defined define VBN cord-005646-xhx9pzhj 3601 19 on on IN cord-005646-xhx9pzhj 3601 20 the the DT cord-005646-xhx9pzhj 3601 21 basis basis NN cord-005646-xhx9pzhj 3601 22 of of IN cord-005646-xhx9pzhj 3601 23 the the DT cord-005646-xhx9pzhj 3601 24 decrease decrease NN cord-005646-xhx9pzhj 3601 25 in in IN cord-005646-xhx9pzhj 3601 26 FiO fio NN cord-005646-xhx9pzhj 3601 27 2 2 CD cord-005646-xhx9pzhj 3601 28 . . . cord-005646-xhx9pzhj 3602 1 Results result NNS cord-005646-xhx9pzhj 3602 2 : : : cord-005646-xhx9pzhj 3603 1 There there EX cord-005646-xhx9pzhj 3603 2 were be VBD cord-005646-xhx9pzhj 3603 3 no no DT cord-005646-xhx9pzhj 3603 4 signif signif NN cord-005646-xhx9pzhj 3603 5 . . . cord-005646-xhx9pzhj 3604 1 differences difference NNS cord-005646-xhx9pzhj 3604 2 in in IN cord-005646-xhx9pzhj 3604 3 patient patient JJ cord-005646-xhx9pzhj 3604 4 population population NN cord-005646-xhx9pzhj 3604 5 and and CC cord-005646-xhx9pzhj 3604 6 initial initial JJ cord-005646-xhx9pzhj 3604 7 parameters parameter NNS cord-005646-xhx9pzhj 3604 8 : : : cord-005646-xhx9pzhj 3604 9 GA GA NNP cord-005646-xhx9pzhj 3604 10 ( ( -LRB- cord-005646-xhx9pzhj 3604 11 29.9+_2.2 29.9+_2.2 CD cord-005646-xhx9pzhj 3604 12 vs vs IN cord-005646-xhx9pzhj 3604 13 29A 29A NNS cord-005646-xhx9pzhj 3604 14 _ _ NNP cord-005646-xhx9pzhj 3604 15 +2,6 +2,6 NNP cord-005646-xhx9pzhj 3604 16 wks wks NN cord-005646-xhx9pzhj 3604 17 ) ) -RRB- cord-005646-xhx9pzhj 3604 18 , , , cord-005646-xhx9pzhj 3604 19 birth birth NN cord-005646-xhx9pzhj 3604 20 weight weight NN cord-005646-xhx9pzhj 3604 21 ( ( -LRB- cord-005646-xhx9pzhj 3604 22 t332_+431 t332_+431 NNP cord-005646-xhx9pzhj 3604 23 vs vs IN cord-005646-xhx9pzhj 3604 24 1227-+444 1227-+444 CD cord-005646-xhx9pzhj 3604 25 g g NNP cord-005646-xhx9pzhj 3604 26 ) ) -RRB- cord-005646-xhx9pzhj 3604 27 , , , cord-005646-xhx9pzhj 3604 28 severity severity NN cord-005646-xhx9pzhj 3604 29 of of IN cord-005646-xhx9pzhj 3604 30 RDS RDS NNP cord-005646-xhx9pzhj 3604 31 ( ( -LRB- cord-005646-xhx9pzhj 3604 32 grade grade NN cord-005646-xhx9pzhj 3604 33 Ill Ill NNP cord-005646-xhx9pzhj 3604 34 - - HYPH cord-005646-xhx9pzhj 3604 35 IV IV NNP cord-005646-xhx9pzhj 3604 36 : : : cord-005646-xhx9pzhj 3604 37 78.6 78.6 CD cord-005646-xhx9pzhj 3604 38 % % NN cord-005646-xhx9pzhj 3604 39 vs vs IN cord-005646-xhx9pzhj 3604 40 80.3 80.3 CD cord-005646-xhx9pzhj 3604 41 % % NN cord-005646-xhx9pzhj 3604 42 ) ) -RRB- cord-005646-xhx9pzhj 3604 43 , , , cord-005646-xhx9pzhj 3604 44 Apgar Apgar NNP cord-005646-xhx9pzhj 3604 45 scores score NNS cord-005646-xhx9pzhj 3604 46 , , , cord-005646-xhx9pzhj 3604 47 cord cord NN cord-005646-xhx9pzhj 3604 48 blood blood NN cord-005646-xhx9pzhj 3604 49 gases gas NNS cord-005646-xhx9pzhj 3604 50 , , , cord-005646-xhx9pzhj 3604 51 initial initial JJ cord-005646-xhx9pzhj 3604 52 ventilatory ventilatory JJ cord-005646-xhx9pzhj 3604 53 settings setting NNS cord-005646-xhx9pzhj 3604 54 . . . cord-005646-xhx9pzhj 3605 1 In in IN cord-005646-xhx9pzhj 3605 2 ' ' CD cord-005646-xhx9pzhj 3605 3 93 93 CD cord-005646-xhx9pzhj 3605 4 however however RB cord-005646-xhx9pzhj 3605 5 , , , cord-005646-xhx9pzhj 3605 6 the the DT cord-005646-xhx9pzhj 3605 7 initial initial JJ cord-005646-xhx9pzhj 3605 8 surfactant surfactant NN cord-005646-xhx9pzhj 3605 9 dose dose NN cord-005646-xhx9pzhj 3605 10 was be VBD cord-005646-xhx9pzhj 3605 11 administered administer VBN cord-005646-xhx9pzhj 3605 12 earlier early RBR cord-005646-xhx9pzhj 3605 13 than than IN cord-005646-xhx9pzhj 3605 14 in in IN cord-005646-xhx9pzhj 3605 15 ' ' CD cord-005646-xhx9pzhj 3605 16 94 94 CD cord-005646-xhx9pzhj 3606 1 ( ( -LRB- cord-005646-xhx9pzhj 3606 2 14.4-+ 14.4-+ CD cord-005646-xhx9pzhj 3606 3 17.4 17.4 CD cord-005646-xhx9pzhj 3606 4 vs vs IN cord-005646-xhx9pzhj 3606 5 6.5_+7.8 6.5_+7.8 CD cord-005646-xhx9pzhj 3606 6 hrs hrs NN cord-005646-xhx9pzhj 3606 7 postpartum postpartum NN cord-005646-xhx9pzhj 3606 8 , , , cord-005646-xhx9pzhj 3606 9 p= p= NNP cord-005646-xhx9pzhj 3606 10 0.025 0.025 CD cord-005646-xhx9pzhj 3606 11 ) ) -RRB- cord-005646-xhx9pzhj 3606 12 . . . cord-005646-xhx9pzhj 3607 1 Although although IN cord-005646-xhx9pzhj 3607 2 the the DT cord-005646-xhx9pzhj 3607 3 average average JJ cord-005646-xhx9pzhj 3607 4 total total JJ cord-005646-xhx9pzhj 3607 5 cumulative cumulative JJ cord-005646-xhx9pzhj 3607 6 dose dose NN cord-005646-xhx9pzhj 3607 7 was be VBD cord-005646-xhx9pzhj 3607 8 equal equal JJ cord-005646-xhx9pzhj 3607 9 in in IN cord-005646-xhx9pzhj 3607 10 ' ' CD cord-005646-xhx9pzhj 3607 11 93 93 CD cord-005646-xhx9pzhj 3607 12 and and CC cord-005646-xhx9pzhj 3607 13 ' ' CD cord-005646-xhx9pzhj 3607 14 94 94 CD cord-005646-xhx9pzhj 3608 1 ( ( -LRB- cord-005646-xhx9pzhj 3608 2 169.3-+65,8 169.3-+65,8 CD cord-005646-xhx9pzhj 3608 3 vs vs IN cord-005646-xhx9pzhj 3608 4 167.4_+69 167.4_+69 CD cord-005646-xhx9pzhj 3608 5 .4 .4 . cord-005646-xhx9pzhj 3609 1 mg mg NNP cord-005646-xhx9pzhj 3609 2 / / SYM cord-005646-xhx9pzhj 3609 3 kg kg NNP cord-005646-xhx9pzhj 3609 4 ) ) -RRB- cord-005646-xhx9pzhj 3609 5 , , , cord-005646-xhx9pzhj 3609 6 more more JJR cord-005646-xhx9pzhj 3609 7 doses dose NNS cord-005646-xhx9pzhj 3609 8 of of IN cord-005646-xhx9pzhj 3609 9 Alvofact Alvofact NNP cord-005646-xhx9pzhj 3609 10 were be VBD cord-005646-xhx9pzhj 3609 11 given give VBN cord-005646-xhx9pzhj 3609 12 compared compare VBN cord-005646-xhx9pzhj 3609 13 to to IN cord-005646-xhx9pzhj 3609 14 Survanta Survanta NNP cord-005646-xhx9pzhj 3609 15 { { -LRB- cord-005646-xhx9pzhj 3609 16 2.3_+1.1 2.3_+1.1 CD cord-005646-xhx9pzhj 3610 1 vs vs IN cord-005646-xhx9pzhj 3610 2 1.7_+0.6 1.7_+0.6 CD cord-005646-xhx9pzhj 3610 3 , , , cord-005646-xhx9pzhj 3610 4 p p NN cord-005646-xhx9pzhj 3610 5 = = SYM cord-005646-xhx9pzhj 3610 6 O.O01 o.o01 NN cord-005646-xhx9pzhj 3610 7 ) ) -RRB- cord-005646-xhx9pzhj 3610 8 and and CC cord-005646-xhx9pzhj 3610 9 more more JJR cord-005646-xhx9pzhj 3610 10 patients patient NNS cord-005646-xhx9pzhj 3610 11 in in IN cord-005646-xhx9pzhj 3610 12 ' ' CD cord-005646-xhx9pzhj 3610 13 93 93 CD cord-005646-xhx9pzhj 3610 14 received receive VBD cord-005646-xhx9pzhj 3610 15 more more JJR cord-005646-xhx9pzhj 3610 16 than than IN cord-005646-xhx9pzhj 3610 17 two two CD cord-005646-xhx9pzhj 3610 18 doses dose NNS cord-005646-xhx9pzhj 3610 19 than than IN cord-005646-xhx9pzhj 3610 20 in in IN cord-005646-xhx9pzhj 3610 21 ' ' CD cord-005646-xhx9pzhj 3610 22 94 94 CD cord-005646-xhx9pzhj 3610 23 ( ( -LRB- cord-005646-xhx9pzhj 3610 24 46 46 CD cord-005646-xhx9pzhj 3610 25 % % NN cord-005646-xhx9pzhj 3610 26 vs vs IN cord-005646-xhx9pzhj 3610 27 18 18 CD cord-005646-xhx9pzhj 3610 28 % % NN cord-005646-xhx9pzhj 3610 29 of of IN cord-005646-xhx9pzhj 3610 30 patients patient NNS cord-005646-xhx9pzhj 3610 31 ) ) -RRB- cord-005646-xhx9pzhj 3610 32 . . . cord-005646-xhx9pzhj 3611 1 There there EX cord-005646-xhx9pzhj 3611 2 was be VBD cord-005646-xhx9pzhj 3611 3 no no DT cord-005646-xhx9pzhj 3611 4 difference difference NN cord-005646-xhx9pzhj 3611 5 in in IN cord-005646-xhx9pzhj 3611 6 the the DT cord-005646-xhx9pzhj 3611 7 incidence incidence NN cord-005646-xhx9pzhj 3611 8 of of IN cord-005646-xhx9pzhj 3611 9 non non JJ cord-005646-xhx9pzhj 3611 10 - - NNS cord-005646-xhx9pzhj 3611 11 putmonarycomplications putmonarycomplication NNS cord-005646-xhx9pzhj 3611 12 . . . cord-005646-xhx9pzhj 3612 1 AIvofact AIvofact NNP cord-005646-xhx9pzhj 3613 1 ( ( -LRB- cord-005646-xhx9pzhj 3613 2 There there EX cord-005646-xhx9pzhj 3613 3 was be VBD cord-005646-xhx9pzhj 3613 4 a a DT cord-005646-xhx9pzhj 3613 5 better well JJR cord-005646-xhx9pzhj 3613 6 initial initial JJ cord-005646-xhx9pzhj 3613 7 response response NN cord-005646-xhx9pzhj 3613 8 to to IN cord-005646-xhx9pzhj 3613 9 Survanta Survanta NNP cord-005646-xhx9pzhj 3613 10 and and CC cord-005646-xhx9pzhj 3613 11 a a DT cord-005646-xhx9pzhj 3613 12 better well JJR cord-005646-xhx9pzhj 3613 13 respiratory respiratory JJ cord-005646-xhx9pzhj 3613 14 outcome outcome NN cord-005646-xhx9pzhj 3613 15 in in IN cord-005646-xhx9pzhj 3613 16 1994 1994 CD cord-005646-xhx9pzhj 3613 17 : : : cord-005646-xhx9pzhj 3613 18 in in IN cord-005646-xhx9pzhj 3613 19 the the DT cord-005646-xhx9pzhj 3613 20 group group NN cord-005646-xhx9pzhj 3614 1 < < NNP cord-005646-xhx9pzhj 3614 2 1250 1250 CD cord-005646-xhx9pzhj 3614 3 g g NNP cord-005646-xhx9pzhj 3614 4 the the DT cord-005646-xhx9pzhj 3614 5 duration duration NN cord-005646-xhx9pzhj 3614 6 of of IN cord-005646-xhx9pzhj 3614 7 ventilation ventilation NN cord-005646-xhx9pzhj 3614 8 was be VBD cord-005646-xhx9pzhj 3614 9 half half NN cord-005646-xhx9pzhj 3614 10 in in IN cord-005646-xhx9pzhj 3614 11 1994 1994 CD cord-005646-xhx9pzhj 3614 12 , , , cord-005646-xhx9pzhj 3614 13 and and CC cord-005646-xhx9pzhj 3614 14 in in IN cord-005646-xhx9pzhj 3614 15 the the DT cord-005646-xhx9pzhj 3614 16 group group NN cord-005646-xhx9pzhj 3615 1 > > XX cord-005646-xhx9pzhj 3615 2 ~125Og ~125Og NFP cord-005646-xhx9pzhj 3616 1 the the DT cord-005646-xhx9pzhj 3616 2 duration duration NN cord-005646-xhx9pzhj 3616 3 of of IN cord-005646-xhx9pzhj 3616 4 extra extra JJ cord-005646-xhx9pzhj 3616 5 O o NN cord-005646-xhx9pzhj 3616 6 2 2 CD cord-005646-xhx9pzhj 3616 7 need need NN cord-005646-xhx9pzhj 3616 8 was be VBD cord-005646-xhx9pzhj 3616 9 half half NN cord-005646-xhx9pzhj 3616 10 in in IN cord-005646-xhx9pzhj 3616 11 1994 1994 CD cord-005646-xhx9pzhj 3616 12 as as IN cord-005646-xhx9pzhj 3616 13 compared compare VBN cord-005646-xhx9pzhj 3616 14 to to IN cord-005646-xhx9pzhj 3616 15 1993 1993 CD cord-005646-xhx9pzhj 3616 16 . . . cord-005646-xhx9pzhj 3617 1 We -PRON- PRP cord-005646-xhx9pzhj 3617 2 speculate speculate VBP cord-005646-xhx9pzhj 3617 3 that that IN cord-005646-xhx9pzhj 3617 4 the the DT cord-005646-xhx9pzhj 3617 5 main main JJ cord-005646-xhx9pzhj 3617 6 reason reason NN cord-005646-xhx9pzhj 3617 7 for for IN cord-005646-xhx9pzhj 3617 8 this this DT cord-005646-xhx9pzhj 3617 9 difference difference NN cord-005646-xhx9pzhj 3617 10 is be VBZ cord-005646-xhx9pzhj 3617 11 the the DT cord-005646-xhx9pzhj 3617 12 earlier early RBR cord-005646-xhx9pzhj 3617 13 and and CC cord-005646-xhx9pzhj 3617 14 initially initially RB cord-005646-xhx9pzhj 3617 15 higher high JJR cord-005646-xhx9pzhj 3617 16 dosing dosing NN cord-005646-xhx9pzhj 3617 17 used use VBN cord-005646-xhx9pzhj 3617 18 with with IN cord-005646-xhx9pzhj 3617 19 Survanta Survanta NNP cord-005646-xhx9pzhj 3617 20 compared compare VBN cord-005646-xhx9pzhj 3617 21 to to IN cord-005646-xhx9pzhj 3617 22 that that DT cord-005646-xhx9pzhj 3617 23 used use VBN cord-005646-xhx9pzhj 3617 24 with with IN cord-005646-xhx9pzhj 3617 25 Alvofact Alvofact NNP cord-005646-xhx9pzhj 3617 26 which which WDT cord-005646-xhx9pzhj 3617 27 was be VBD cord-005646-xhx9pzhj 3617 28 given give VBN cord-005646-xhx9pzhj 3617 29 in in IN cord-005646-xhx9pzhj 3617 30 the the DT cord-005646-xhx9pzhj 3617 31 same same JJ cord-005646-xhx9pzhj 3617 32 total total JJ cord-005646-xhx9pzhj 3617 33 cumulative cumulative JJ cord-005646-xhx9pzhj 3617 34 dose dose NN cord-005646-xhx9pzhj 3617 35 but but CC cord-005646-xhx9pzhj 3617 36 over over IN cord-005646-xhx9pzhj 3617 37 a a DT cord-005646-xhx9pzhj 3617 38 larger large JJR cord-005646-xhx9pzhj 3617 39 time time NN cord-005646-xhx9pzhj 3617 40 span span NN cord-005646-xhx9pzhj 3617 41 . . . cord-005646-xhx9pzhj 3618 1 Background background NN cord-005646-xhx9pzhj 3618 2 : : : cord-005646-xhx9pzhj 3619 1 E×ogerlous e×ogerlous JJ cord-005646-xhx9pzhj 3620 1 sur&ct sur&ct LS cord-005646-xhx9pzhj 3620 2 ~ ~ NFP cord-005646-xhx9pzhj 3620 3 t t XX cord-005646-xhx9pzhj 3620 4 raplacem raplacem NNP cord-005646-xhx9pzhj 3621 1 ~t ~t NNP cord-005646-xhx9pzhj 3621 2 treatmem treatmem NNP cord-005646-xhx9pzhj 3621 3 has have VBZ cord-005646-xhx9pzhj 3621 4 become become VBN cord-005646-xhx9pzhj 3621 5 rou rou NNP cord-005646-xhx9pzhj 3622 1 ~ne ~ne NNP cord-005646-xhx9pzhj 3622 2 k~ k~ XX cord-005646-xhx9pzhj 3623 1 the the DT cord-005646-xhx9pzhj 3623 2 t~ t~ XX cord-005646-xhx9pzhj 3624 1 eatme~ eatme~ NNP cord-005646-xhx9pzhj 3625 1 t t NNP cord-005646-xhx9pzhj 3625 2 of of IN cord-005646-xhx9pzhj 3625 3 respira~"¢ respira~"¢ NNP cord-005646-xhx9pzhj 3625 4 dim'~ dim'~ NNP cord-005646-xhx9pzhj 3625 5 syndrome syndrome NN cord-005646-xhx9pzhj 3626 1 ( ( -LRB- cord-005646-xhx9pzhj 3626 2 I i NN cord-005646-xhx9pzhj 3626 3 ~ ~ CD cord-005646-xhx9pzhj 3626 4 DS DS NNP cord-005646-xhx9pzhj 3626 5 ) ) -RRB- cord-005646-xhx9pzhj 3626 6 of of IN cord-005646-xhx9pzhj 3626 7 pr pr NNP cord-005646-xhx9pzhj 3626 8 ~ ~ NNP cord-005646-xhx9pzhj 3626 9 e e NN cord-005646-xhx9pzhj 3626 10 ~ ~ NNP cord-005646-xhx9pzhj 3626 11 tur~ tur~ CD cord-005646-xhx9pzhj 3626 12 , , , cord-005646-xhx9pzhj 3626 13 wh wh NNP cord-005646-xhx9pzhj 3626 14 ~ ~ NFP cord-005646-xhx9pzhj 3626 15 eas eas NNP cord-005646-xhx9pzhj 3626 16 its -PRON- PRP$ cord-005646-xhx9pzhj 3626 17 effica effica NNP cord-005646-xhx9pzhj 3627 1 W w NN cord-005646-xhx9pzhj 3627 2 th th DT cord-005646-xhx9pzhj 3627 3 odi~ odi~ CD cord-005646-xhx9pzhj 3627 4 respiratory respiratory JJ cord-005646-xhx9pzhj 3627 5 diseoses diseose NNS cord-005646-xhx9pzhj 3627 6 is be VBZ cord-005646-xhx9pzhj 3627 7 sdi1 sdi1 NN cord-005646-xhx9pzhj 3627 8 being be VBG cord-005646-xhx9pzhj 3627 9 wader wader NN cord-005646-xhx9pzhj 3627 10 mvesUgatio~. mvesUgatio~. NNP cord-005646-xhx9pzhj 3627 11 Objective objective NN cord-005646-xhx9pzhj 3627 12 : : : cord-005646-xhx9pzhj 3627 13 " " `` cord-005646-xhx9pzhj 3627 14 Eac~ Eac~ NNP cord-005646-xhx9pzhj 3627 15 mt mt NNP cord-005646-xhx9pzhj 3627 16 ereat ereat NNP cord-005646-xhx9pzhj 3627 17 isto isto NNP cord-005646-xhx9pzhj 3627 18 report report NNP cord-005646-xhx9pzhj 3627 19 ottr ottr NN cord-005646-xhx9pzhj 3627 20 results result NNS cord-005646-xhx9pzhj 3627 21 of of IN cord-005646-xhx9pzhj 3627 22 prospect prospect NN cord-005646-xhx9pzhj 3627 23 / / SYM cord-005646-xhx9pzhj 3627 24 re re IN cord-005646-xhx9pzhj 3627 25 , , , cord-005646-xhx9pzhj 3627 26 non non JJ cord-005646-xhx9pzhj 3627 27 - - JJ cord-005646-xhx9pzhj 3627 28 randomized randomized JJ cord-005646-xhx9pzhj 3627 29 " " '' cord-005646-xhx9pzhj 3627 30 re~-o.e re~-o.e NNP cord-005646-xhx9pzhj 3627 31 " " '' cord-005646-xhx9pzhj 3627 32 study study NN cord-005646-xhx9pzhj 3627 33 oE oe CD cord-005646-xhx9pzhj 3627 34 suffact suffact JJ cord-005646-xhx9pzhj 3627 35 ~ ~ NFP cord-005646-xhx9pzhj 3627 36 t t XX cord-005646-xhx9pzhj 3627 37 replacement replacement NN cord-005646-xhx9pzhj 3627 38 in in IN cord-005646-xhx9pzhj 3627 39 outhom outhom JJ cord-005646-xhx9pzhj 3627 40 premamae premamae NNP cord-005646-xhx9pzhj 3627 41 infa~ infa~ NNP cord-005646-xhx9pzhj 3628 1 t~ t~ ADD cord-005646-xhx9pzhj 3629 1 with with IN cord-005646-xhx9pzhj 3629 2 RDS RDS NNP cord-005646-xhx9pzhj 3629 3 reRuirmg reRuirmg NNP cord-005646-xhx9pzhj 3629 4 me -PRON- PRP cord-005646-xhx9pzhj 3629 5 ~ ~ NFP cord-005646-xhx9pzhj 3629 6 aical aical NNP cord-005646-xhx9pzhj 3629 7 ventilatioa ventilatioa NNP cord-005646-xhx9pzhj 3629 8 ( ( -LRB- cord-005646-xhx9pzhj 3629 9 NfV nfv NN cord-005646-xhx9pzhj 3629 10 ) ) -RRB- cord-005646-xhx9pzhj 3629 11 . . . cord-005646-xhx9pzhj 3630 1 P~ p~ DT cord-005646-xhx9pzhj 3631 1 tien~ tien~ NNP cord-005646-xhx9pzhj 3632 1 and and CC cord-005646-xhx9pzhj 3632 2 metho0.s metho0. VBN cord-005646-xhx9pzhj 3632 3 : : : cord-005646-xhx9pzhj 3632 4 From from IN cord-005646-xhx9pzhj 3632 5 J J NNP cord-005646-xhx9pzhj 3632 6 - - HYPH cord-005646-xhx9pzhj 3632 7 aly aly NNP cord-005646-xhx9pzhj 3632 8 1993 1993 CD cord-005646-xhx9pzhj 3632 9 tO to IN cord-005646-xhx9pzhj 3632 10 June June NNP cord-005646-xhx9pzhj 3632 11 1995 1995 CD cord-005646-xhx9pzhj 3632 12 , , , cord-005646-xhx9pzhj 3632 13 18/58 18/58 CD cord-005646-xhx9pzhj 3632 14 ; ; : cord-005646-xhx9pzhj 3632 15 ( ( -LRB- cord-005646-xhx9pzhj 3632 16 31 31 CD cord-005646-xhx9pzhj 3632 17 % % NN cord-005646-xhx9pzhj 3632 18 ) ) -RRB- cord-005646-xhx9pzhj 3632 19 out~ out~ CD cord-005646-xhx9pzhj 3633 1 ~¢ ~¢ NFP cord-005646-xhx9pzhj 3633 2 infaats infaats NNP cord-005646-xhx9pzhj 3633 3 , , , cord-005646-xhx9pzhj 3633 4 at at IN cord-005646-xhx9pzhj 3633 5 a a DT cord-005646-xhx9pzhj 3633 6 mesa mesa NNP cord-005646-xhx9pzhj 3633 7 age age NN cord-005646-xhx9pzhj 3633 8 of of IN cord-005646-xhx9pzhj 3633 9 22 22 CD cord-005646-xhx9pzhj 3633 10 z z NN cord-005646-xhx9pzhj 3633 11 2,7 2,7 CD cord-005646-xhx9pzhj 3633 12 horn horn NN cord-005646-xhx9pzhj 3633 13 's 's POS cord-005646-xhx9pzhj 3633 14 ( ( -LRB- cord-005646-xhx9pzhj 3633 15 13 13 CD cord-005646-xhx9pzhj 3633 16 boys boy NNS cord-005646-xhx9pzhj 3633 17 , , , cord-005646-xhx9pzhj 3633 18 5 5 CD cord-005646-xhx9pzhj 3633 19 ~rls ~rl NNS cord-005646-xhx9pzhj 3633 20 ; ; : cord-005646-xhx9pzhj 3633 21 ~ ~ NFP cord-005646-xhx9pzhj 3634 1 gestafioaN gestafioan CD cord-005646-xhx9pzhj 3634 2 age age NN cord-005646-xhx9pzhj 3634 3 32-+2.8 32-+2.8 CD cord-005646-xhx9pzhj 3634 4 weeks week NNS cord-005646-xhx9pzhj 3634 5 , , , cord-005646-xhx9pzhj 3634 6 mera~ mera~ NN cord-005646-xhx9pzhj 3634 7 birth birth NN cord-005646-xhx9pzhj 3634 8 weight weight NN cord-005646-xhx9pzhj 3634 9 1846 1846 CD cord-005646-xhx9pzhj 3635 1 _ _ NNP cord-005646-xhx9pzhj 3635 2 + + CC cord-005646-xhx9pzhj 3636 1 544 544 CD cord-005646-xhx9pzhj 3636 2 g g NN cord-005646-xhx9pzhj 3636 3 , , , cord-005646-xhx9pzhj 3636 4 ~ ~ NFP cord-005646-xhx9pzhj 3636 5 7.2 7.2 CD cord-005646-xhx9pzhj 3636 6 i i NNP cord-005646-xhx9pzhj 3636 7 " " '' cord-005646-xhx9pzhj 3636 8 17 17 CD cord-005646-xhx9pzhj 3636 9 at at IN cord-005646-xhx9pzhj 3636 10 5 5 CD cord-005646-xhx9pzhj 3636 11 minutes minute NNS cord-005646-xhx9pzhj 3636 12 ) ) -RRB- cord-005646-xhx9pzhj 3636 13 with with IN cord-005646-xhx9pzhj 3636 14 RDS RDS NNP cord-005646-xhx9pzhj 3636 15 , , , cord-005646-xhx9pzhj 3636 16 requiring require VBG cord-005646-xhx9pzhj 3636 17 MV MV NNP cord-005646-xhx9pzhj 3636 18 , , , cord-005646-xhx9pzhj 3636 19 received receive VBD cord-005646-xhx9pzhj 3636 20 bov bov NNP cord-005646-xhx9pzhj 3636 21 ~ ~ NNP cord-005646-xhx9pzhj 3636 22 e e NNP cord-005646-xhx9pzhj 3636 23 - - NN cord-005646-xhx9pzhj 3636 24 suff suff NNP cord-005646-xhx9pzhj 3636 25 ~ ~ NFP cord-005646-xhx9pzhj 3636 26 amt amt NNP cord-005646-xhx9pzhj 3636 27 ( ( -LRB- cord-005646-xhx9pzhj 3636 28 Survanta Survanta NNP cord-005646-xhx9pzhj 3636 29 , , , cord-005646-xhx9pzhj 3636 30 Ros~/AbotI Ros~/AbotI NNP cord-005646-xhx9pzhj 3636 31 , , , cord-005646-xhx9pzhj 3637 1 Laboratotie~ laboratotie~ DT cord-005646-xhx9pzhj 3637 2 Columbus Columbus NNP cord-005646-xhx9pzhj 3637 3 , , , cord-005646-xhx9pzhj 3637 4 Ohio Ohio NNP cord-005646-xhx9pzhj 3637 5 ) ) -RRB- cord-005646-xhx9pzhj 3638 1 eadotracheally eadotracheally RB cord-005646-xhx9pzhj 3638 2 , , , cord-005646-xhx9pzhj 3638 3 as as IN cord-005646-xhx9pzhj 3638 4 was be VBD cord-005646-xhx9pzhj 3638 5 recomm recomm NNP cord-005646-xhx9pzhj 3638 6 ~ ~ NFP cord-005646-xhx9pzhj 3638 7 aded ade VBN cord-005646-xhx9pzhj 3638 8 by by IN cord-005646-xhx9pzhj 3638 9 maaufacturer maaufacturer NNP cord-005646-xhx9pzhj 3638 10 . . . cord-005646-xhx9pzhj 3639 1 As as IN cord-005646-xhx9pzhj 3639 2 the the DT cord-005646-xhx9pzhj 3639 3 c,~:ttrol c,~:ttrol NNP cord-005646-xhx9pzhj 3639 4 group group NN cord-005646-xhx9pzhj 3639 5 19 19 CD cord-005646-xhx9pzhj 3639 6 o o NN cord-005646-xhx9pzhj 3639 7 ~ ~ NFP cord-005646-xhx9pzhj 3639 8 bom bom NNP cord-005646-xhx9pzhj 3639 9 premature premature JJ cord-005646-xhx9pzhj 3639 10 infants infant NNS cord-005646-xhx9pzhj 3639 11 ( ( -LRB- cord-005646-xhx9pzhj 3639 12 ot~ ot~ NN cord-005646-xhx9pzhj 3639 13 of of IN cord-005646-xhx9pzhj 3639 14 49 49 CD cord-005646-xhx9pzhj 3639 15 ; ; : cord-005646-xhx9pzhj 3639 16 39 39 CD cord-005646-xhx9pzhj 3639 17 % % NN cord-005646-xhx9pzhj 3639 18 , , , cord-005646-xhx9pzhj 3639 19 admitted admit VBN cord-005646-xhx9pzhj 3639 20 with with IN cord-005646-xhx9pzhj 3639 21 RDS RDS NNP cord-005646-xhx9pzhj 3639 22 from from IN cord-005646-xhx9pzhj 3639 23 Euiy Euiy NNP cord-005646-xhx9pzhj 3639 24 1991 1991 CD cord-005646-xhx9pzhj 3639 25 to to IN cord-005646-xhx9pzhj 3639 26 Eune Eune NNP cord-005646-xhx9pzhj 3639 27 1991 1991 CD cord-005646-xhx9pzhj 3639 28 ) ) -RRB- cord-005646-xhx9pzhj 3639 29 were be VBD cord-005646-xhx9pzhj 3639 30 saelected saelecte VBN cord-005646-xhx9pzhj 3639 31 ~d ~d ADD cord-005646-xhx9pzhj 3639 32 who who WP cord-005646-xhx9pzhj 3639 33 did do VBD cord-005646-xhx9pzhj 3639 34 not not RB cord-005646-xhx9pzhj 3639 35 receive receive VB cord-005646-xhx9pzhj 3639 36 surfaaam surfaaam JJ cord-005646-xhx9pzhj 3639 37 , , , cord-005646-xhx9pzhj 3639 38 Compared compare VBN cord-005646-xhx9pzhj 3639 39 with with IN cord-005646-xhx9pzhj 3639 40 ~hctant ~hctant CD cord-005646-xhx9pzhj 3640 1 ~'oup ~'oup NFP cord-005646-xhx9pzhj 3640 2 they -PRON- PRP cord-005646-xhx9pzhj 3640 3 were be VBD cord-005646-xhx9pzhj 3640 4 admitted admit VBN cord-005646-xhx9pzhj 3640 5 for for IN cord-005646-xhx9pzhj 3640 6 treatmeat treatmeat NNP cord-005646-xhx9pzhj 3640 7 e~'li~ e~'li~ : cord-005646-xhx9pzhj 3640 8 " " `` cord-005646-xhx9pzhj 3640 9 aft~ aft~ NNP cord-005646-xhx9pzhj 3640 10 " " '' cord-005646-xhx9pzhj 3640 11 daliv~:y daliv~:y NNP cord-005646-xhx9pzhj 3640 12 ( ( -LRB- cord-005646-xhx9pzhj 3640 13 at at IN cord-005646-xhx9pzhj 3640 14 the the DT cord-005646-xhx9pzhj 3640 15 age age NN cord-005646-xhx9pzhj 3641 1 6.4::2.2 6.4::2.2 CD cord-005646-xhx9pzhj 3641 2 hours hour NNS cord-005646-xhx9pzhj 3641 3 vs. vs. CC cord-005646-xhx9pzhj 3641 4 11.7 11.7 CD cord-005646-xhx9pzhj 3641 5 + + SYM cord-005646-xhx9pzhj 3641 6 -13 -13 CD cord-005646-xhx9pzhj 3641 7 hours hour NNS cord-005646-xhx9pzhj 3641 8 ) ) -RRB- cord-005646-xhx9pzhj 3641 9 , , , cord-005646-xhx9pzhj 3641 10 but but CC cord-005646-xhx9pzhj 3641 11 they -PRON- PRP cord-005646-xhx9pzhj 3641 12 did do VBD cord-005646-xhx9pzhj 3641 13 not not RB cord-005646-xhx9pzhj 3641 14 diff~ diff~ RB cord-005646-xhx9pzhj 3641 15 in in IN cord-005646-xhx9pzhj 3641 16 othe~ othe~ NN cord-005646-xhx9pzhj 3642 1 baseline baseline NNP cord-005646-xhx9pzhj 3642 2 dam'a dam'a NNS cord-005646-xhx9pzhj 3642 3 ~ ~ NFP cord-005646-xhx9pzhj 3642 4 eri eri NNP cord-005646-xhx9pzhj 3642 5 ~ ~ NNP cord-005646-xhx9pzhj 3642 6 cs cs NNP cord-005646-xhx9pzhj 3642 7 at at IN cord-005646-xhx9pzhj 3642 8 ~ti ~ti NNP cord-005646-xhx9pzhj 3643 1 ~ion ~ion NNP cord-005646-xhx9pzhj 3643 2 . . . cord-005646-xhx9pzhj 3644 1 Entry entry NN cord-005646-xhx9pzhj 3644 2 crkeda crkeda NN cord-005646-xhx9pzhj 3644 3 for for IN cord-005646-xhx9pzhj 3644 4 ~¢fa ~¢fa ADD cord-005646-xhx9pzhj 3645 1 ~ ~ NFP cord-005646-xhx9pzhj 3646 1 aut aut NNP cord-005646-xhx9pzhj 3647 1 ~hcadou ~hcadou NNP cord-005646-xhx9pzhj 3647 2 were be VBD cord-005646-xhx9pzhj 3647 3 fractional fractional JJ cord-005646-xhx9pzhj 3647 4 i i NN cord-005646-xhx9pzhj 3647 5 ~ ~ NFP cord-005646-xhx9pzhj 3647 6 firat firat NNP cord-005646-xhx9pzhj 3648 1 o~ o~ LS cord-005646-xhx9pzhj 3648 2 oxTgem oxtgem CD cord-005646-xhx9pzhj 3648 3 r r NN cord-005646-xhx9pzhj 3649 1 ~emeats ~emeats NFP cord-005646-xhx9pzhj 3649 2 -FiO2 -fio2 XX cord-005646-xhx9pzhj 3649 3 > > XX cord-005646-xhx9pzhj 3649 4 0.50 0.50 CD cord-005646-xhx9pzhj 3649 5 -0.60 -0.60 CD cord-005646-xhx9pzhj 3649 6 , , , cord-005646-xhx9pzhj 3649 7 ratio ratio NN cord-005646-xhx9pzhj 3649 8 au au NN cord-005646-xhx9pzhj 3649 9 - - HYPH cord-005646-xhx9pzhj 3649 10 lerlal lerlal NN cord-005646-xhx9pzhj 3649 11 to to IN cord-005646-xhx9pzhj 3649 12 alveolar alveolar NN cord-005646-xhx9pzhj 3649 13 oxygea oxygea NNS cord-005646-xhx9pzhj 3650 1 pre pre JJ cord-005646-xhx9pzhj 3650 2 ~ ~ NFP cord-005646-xhx9pzhj 3650 3 are~ are~ NN cord-005646-xhx9pzhj 3651 1 aO2~AO2 aO2~AO2 NNP cord-005646-xhx9pzhj 3651 2 < < XX cord-005646-xhx9pzhj 3651 3 0,20 0,20 XX cord-005646-xhx9pzhj 3652 1 ~ad ~ad NNP cord-005646-xhx9pzhj 3652 2 oxyge~ oxyge~ NNP cord-005646-xhx9pzhj 3653 1 at,~ at,~ NNP cord-005646-xhx9pzhj 3653 2 i~.dex i~.dex '' cord-005646-xhx9pzhj 3653 3 -Ol -ol IN cord-005646-xhx9pzhj 3653 4 > > XX cord-005646-xhx9pzhj 3654 1 10 10 CD cord-005646-xhx9pzhj 3654 2 . . . cord-005646-xhx9pzhj 3655 1 Primary primary JJ cord-005646-xhx9pzhj 3655 2 o o NN cord-005646-xhx9pzhj 3656 1 ~comes ~comes NNP cord-005646-xhx9pzhj 3656 2 were be VBD cord-005646-xhx9pzhj 3656 3 deter deter VB cord-005646-xhx9pzhj 3656 4 ~ ~ NFP cord-005646-xhx9pzhj 3656 5 caned cane VBN cord-005646-xhx9pzhj 3656 6 by by IN cord-005646-xhx9pzhj 3656 7 ~hanges ~hanges NNP cord-005646-xhx9pzhj 3656 8 m m NNP cord-005646-xhx9pzhj 3656 9 exs'ge exs'ge CD cord-005646-xhx9pzhj 3657 1 ~ab ~ab NNP cord-005646-xhx9pzhj 3657 2 , , , cord-005646-xhx9pzhj 3658 1 c~ c~ XX cord-005646-xhx9pzhj 3659 1 ~r ~r XX cord-005646-xhx9pzhj 3660 1 ~d ~d NFP cord-005646-xhx9pzhj 3660 2 vmtilatic~ vmtilatic~ NNP cord-005646-xhx9pzhj 3660 3 ~ ~ NFP cord-005646-xhx9pzhj 3660 4 the the DT cord-005646-xhx9pzhj 3660 5 following follow VBG cord-005646-xhx9pzhj 3660 6 variable~ variable~ NNP cord-005646-xhx9pzhj 3660 7 ; ; : cord-005646-xhx9pzhj 3660 8 ( ( -LRB- cord-005646-xhx9pzhj 3660 9 1 1 LS cord-005646-xhx9pzhj 3660 10 ) ) -RRB- cord-005646-xhx9pzhj 3660 11 fi'aaic~ fi'aaic~ NN cord-005646-xhx9pzhj 3660 12 of of IN cord-005646-xhx9pzhj 3660 13 i i NNP cord-005646-xhx9pzhj 3660 14 ~ ~ NFP cord-005646-xhx9pzhj 3660 15 spired spired NNP cord-005646-xhx9pzhj 3660 16 oxTge~ oxTge~ NNP cord-005646-xhx9pzhj 3660 17 ( ( -LRB- cord-005646-xhx9pzhj 3660 18 FiO2 FiO2 NNP cord-005646-xhx9pzhj 3660 19 ) ) -RRB- cord-005646-xhx9pzhj 3660 20 ; ; : cord-005646-xhx9pzhj 3660 21 ( ( -LRB- cord-005646-xhx9pzhj 3660 22 2 2 LS cord-005646-xhx9pzhj 3660 23 ) ) -RRB- cord-005646-xhx9pzhj 3660 24 mesa mesa NNP cord-005646-xhx9pzhj 3660 25 Nnvay Nnvay NNP cord-005646-xhx9pzhj 3660 26 presmzre presmzre NNS cord-005646-xhx9pzhj 3660 27 ( ( -LRB- cord-005646-xhx9pzhj 3660 28 MAP MAP NNP cord-005646-xhx9pzhj 3660 29 ) ) -RRB- cord-005646-xhx9pzhj 3661 1 ( ( -LRB- cord-005646-xhx9pzhj 3661 2 3 3 LS cord-005646-xhx9pzhj 3661 3 ) ) -RRB- cord-005646-xhx9pzhj 3661 4 paG2 paG2 VBZ cord-005646-xhx9pzhj 3661 5 ~AO2 ~ao2 CD cord-005646-xhx9pzhj 3661 6 ratio ratio NN cord-005646-xhx9pzhj 3661 7 , , , cord-005646-xhx9pzhj 3661 8 ( ( -LRB- cord-005646-xhx9pzhj 3661 9 4 4 LS cord-005646-xhx9pzhj 3661 10 ) ) -RRB- cord-005646-xhx9pzhj 3661 11 oxyge oxyge NNPS cord-005646-xhx9pzhj 3661 12 ~ ~ NFP cord-005646-xhx9pzhj 3661 13 ion ion NN cord-005646-xhx9pzhj 3661 14 index index NN cord-005646-xhx9pzhj 3661 15 ( ( -LRB- cord-005646-xhx9pzhj 3661 16 OI OI NNP cord-005646-xhx9pzhj 3661 17 ) ) -RRB- cord-005646-xhx9pzhj 3661 18 . . . cord-005646-xhx9pzhj 3662 1 Commo~ commo~ JJ cord-005646-xhx9pzhj 3663 1 compHcadces comphcadce NNS cord-005646-xhx9pzhj 3663 2 of of IN cord-005646-xhx9pzhj 3663 3 prem prem NNP cord-005646-xhx9pzhj 3663 4 , , , cord-005646-xhx9pzhj 3663 5 muSty muSty NNP cord-005646-xhx9pzhj 3664 1 ~d ~d NNP cord-005646-xhx9pzhj 3664 2 con con NNP cord-005646-xhx9pzhj 3664 3 ~ ~ NFP cord-005646-xhx9pzhj 3664 4 ol ol NNP cord-005646-xhx9pzhj 3664 5 mechamcal mechamcal NNP cord-005646-xhx9pzhj 3664 6 v v NNP cord-005646-xhx9pzhj 3664 7 ~ ~ NFP cord-005646-xhx9pzhj 3664 8 ati]al ati]al NNP cord-005646-xhx9pzhj 3664 9 ~ ~ NFP cord-005646-xhx9pzhj 3664 10 on on IN cord-005646-xhx9pzhj 3664 11 ( ( -LRB- cord-005646-xhx9pzhj 3664 12 pater pater NNP cord-005646-xhx9pzhj 3664 13 dumas dumas NNP cord-005646-xhx9pzhj 3664 14 merios.s merios.s NNP cord-005646-xhx9pzhj 3664 15 , , , cord-005646-xhx9pzhj 3665 1 intracr intracr NNP cord-005646-xhx9pzhj 3666 1 ~nlal ~nlal NFP cord-005646-xhx9pzhj 3666 2 haemcrn haemcrn NNS cord-005646-xhx9pzhj 3666 3 : : : cord-005646-xhx9pzhj 3666 4 hage hage NNP cord-005646-xhx9pzhj 3666 5 , , , cord-005646-xhx9pzhj 3666 6 air air NN cord-005646-xhx9pzhj 3666 7 leak leak NN cord-005646-xhx9pzhj 3666 8 , , , cord-005646-xhx9pzhj 3666 9 br br NNP cord-005646-xhx9pzhj 3666 10 onchop onchop NNP cord-005646-xhx9pzhj 3667 1 ulmrmm'y ulmrmm'y NNP cord-005646-xhx9pzhj 3667 2 dy dy NNP cord-005646-xhx9pzhj 3667 3 ~ ~ NNP cord-005646-xhx9pzhj 3667 4 pl pl NNP cord-005646-xhx9pzhj 3667 5 ~ ~ NFP cord-005646-xhx9pzhj 3667 6 a a DT cord-005646-xhx9pzhj 3667 7 ~d ~d NNP cord-005646-xhx9pzhj 3667 8 death death NN cord-005646-xhx9pzhj 3667 9 ) ) -RRB- cord-005646-xhx9pzhj 3667 10 were be VBD cord-005646-xhx9pzhj 3667 11 reg~ reg~ CD cord-005646-xhx9pzhj 3668 1 ded ded NNP cord-005646-xhx9pzhj 3668 2 as as IN cord-005646-xhx9pzhj 3668 3 sec sec NNP cord-005646-xhx9pzhj 3668 4 ~ ~ NFP cord-005646-xhx9pzhj 3668 5 d,~y d,~y CD cord-005646-xhx9pzhj 3668 6 outcomes outcome NNS cord-005646-xhx9pzhj 3668 7 . . . cord-005646-xhx9pzhj 3669 1 R R NNP cord-005646-xhx9pzhj 3669 2 ~ ~ CD cord-005646-xhx9pzhj 3669 3 suas suas XX cord-005646-xhx9pzhj 3669 4 : : : cord-005646-xhx9pzhj 3670 1 In in IN cord-005646-xhx9pzhj 3670 2 warfactaat warfactaat NNP cord-005646-xhx9pzhj 3670 3 group group NN cord-005646-xhx9pzhj 3670 4 we -PRON- PRP cord-005646-xhx9pzhj 3670 5 observed observe VBD cord-005646-xhx9pzhj 3670 6 slg~5.c slg~5.c NNP cord-005646-xhx9pzhj 3670 7 ~ ~ NFP cord-005646-xhx9pzhj 3670 8 t t XX cord-005646-xhx9pzhj 3670 9 improve improve VB cord-005646-xhx9pzhj 3670 10 ~ ~ CD cord-005646-xhx9pzhj 3670 11 aeat aeat NNP cord-005646-xhx9pzhj 3670 12 ( ( -LRB- cord-005646-xhx9pzhj 3670 13 p<0.05 p<0.05 NNP cord-005646-xhx9pzhj 3670 14 ) ) -RRB- cord-005646-xhx9pzhj 3670 15 in in IN cord-005646-xhx9pzhj 3670 16 oxygea oxygea NNP cord-005646-xhx9pzhj 3670 17 ~ ~ NFP cord-005646-xhx9pzhj 3670 18 thia thia NNP cord-005646-xhx9pzhj 3670 19 md md NNP cord-005646-xhx9pzhj 3670 20 veaatilation veaatilation NN cord-005646-xhx9pzhj 3670 21 at at IN cord-005646-xhx9pzhj 3670 22 24 24 CD cord-005646-xhx9pzhj 3670 23 hours hour NNS cord-005646-xhx9pzhj 3670 24 all~ all~ CD cord-005646-xhx9pzhj 3670 25 e e NN cord-005646-xhx9pzhj 3671 1 ~try ~try NNP cord-005646-xhx9pzhj 3671 2 k k XX cord-005646-xhx9pzhj 3671 3 ~ ~ NFP cord-005646-xhx9pzhj 3671 4 tO to IN cord-005646-xhx9pzhj 3671 5 the the DT cord-005646-xhx9pzhj 3671 6 m m NNP cord-005646-xhx9pzhj 3671 7 ~ ~ NNP cord-005646-xhx9pzhj 3671 8 dy dy NNP cord-005646-xhx9pzhj 3671 9 in in IN cord-005646-xhx9pzhj 3671 10 compari compari NNP cord-005646-xhx9pzhj 3671 11 ~ ~ NFP cord-005646-xhx9pzhj 3671 12 ion ion NN cord-005646-xhx9pzhj 3671 13 to to IN cord-005646-xhx9pzhj 3671 14 nons non NNS cord-005646-xhx9pzhj 3671 15 ~ ~ NFP cord-005646-xhx9pzhj 3671 16 fa fa NN cord-005646-xhx9pzhj 3671 17 ~ ~ NN cord-005646-xhx9pzhj 3671 18 m m NN cord-005646-xhx9pzhj 3671 19 " " '' cord-005646-xhx9pzhj 3671 20 group group NN cord-005646-xhx9pzhj 3671 21 . . . cord-005646-xhx9pzhj 3672 1 Compa Compa NNP cord-005646-xhx9pzhj 3672 2 ~ ~ NFP cord-005646-xhx9pzhj 3672 3 on on IN cord-005646-xhx9pzhj 3672 4 of of IN cord-005646-xhx9pzhj 3672 5 secondao secondao NN cord-005646-xhx9pzhj 3672 6 ' ' '' cord-005646-xhx9pzhj 3672 7 outcomes outcome NNS cord-005646-xhx9pzhj 3672 8 in in IN cord-005646-xhx9pzhj 3672 9 ~ts ~ts NN cord-005646-xhx9pzhj 3672 10 with with IN cord-005646-xhx9pzhj 3672 11 P p NN cord-005646-xhx9pzhj 3672 12 , , , cord-005646-xhx9pzhj 3672 13 . . . cord-005646-xhx9pzhj 3673 1 DS DS NNP cord-005646-xhx9pzhj 3673 2 showes showes NNP cord-005646-xhx9pzhj 3674 1 Table table NN cord-005646-xhx9pzhj 3674 2 l l NN cord-005646-xhx9pzhj 3675 1 We -PRON- PRP cord-005646-xhx9pzhj 3675 2 did do VBD cord-005646-xhx9pzhj 3675 3 not not RB cord-005646-xhx9pzhj 3675 4 observe observe VB cord-005646-xhx9pzhj 3675 5 ~y ~y NNP cord-005646-xhx9pzhj 3675 6 major major JJ cord-005646-xhx9pzhj 3675 7 acute acute JJ cord-005646-xhx9pzhj 3675 8 hfe hfe NNP cord-005646-xhx9pzhj 3675 9 fl fl NNP cord-005646-xhx9pzhj 3675 10 : : : cord-005646-xhx9pzhj 3675 11 u u NNP cord-005646-xhx9pzhj 3675 12 - - HYPH cord-005646-xhx9pzhj 3675 13 eattming eattme VBG cord-005646-xhx9pzhj 3675 14 complicatlola complicatlola NNP cord-005646-xhx9pzhj 3675 15 , , , cord-005646-xhx9pzhj 3675 16 s s NNP cord-005646-xhx9pzhj 3675 17 m m NNP cord-005646-xhx9pzhj 3675 18 sxlrlhct sxlrlhct NNP cord-005646-xhx9pzhj 3676 1 ~mt ~mt JJ cord-005646-xhx9pzhj 3676 2 grou~ grou~ NN cord-005646-xhx9pzhj 3676 3 tr tr NNP cord-005646-xhx9pzhj 3676 4 / / SYM cord-005646-xhx9pzhj 3676 5 lmediately lmediately RB cord-005646-xhx9pzhj 3676 6 after after IN cord-005646-xhx9pzhj 3676 7 stu'~actsmt stu'~actsmt NNP cord-005646-xhx9pzhj 3676 8 rcplacemev_t rcplacemev_t NNP cord-005646-xhx9pzhj 3676 9 therapy therapy NN cord-005646-xhx9pzhj 3676 10 . . . cord-005646-xhx9pzhj 3677 1 The the DT cord-005646-xhx9pzhj 3677 2 duramm duramm NNS cord-005646-xhx9pzhj 3677 3 of of IN cord-005646-xhx9pzhj 3677 4 mechmucal mechmucal FW cord-005646-xhx9pzhj 3677 5 ven ven FW cord-005646-xhx9pzhj 3677 6 ~ ~ NFP cord-005646-xhx9pzhj 3677 7 ation ation NN cord-005646-xhx9pzhj 3678 1 ~ad ~ad NNP cord-005646-xhx9pzhj 3679 1 oxygen oxygen NNP cord-005646-xhx9pzhj 3679 2 Lreau Lreau NNP cord-005646-xhx9pzhj 3679 3 ~ ~ NFP cord-005646-xhx9pzhj 3679 4 ent ent NNP cord-005646-xhx9pzhj 3679 5 m m NNP cord-005646-xhx9pzhj 3679 6 survivals survival NNS cord-005646-xhx9pzhj 3679 7 of of IN cord-005646-xhx9pzhj 3679 8 both both DT cord-005646-xhx9pzhj 3679 9 groups group NNS cord-005646-xhx9pzhj 3680 1 did do VBD cord-005646-xhx9pzhj 3680 2 not not RB cord-005646-xhx9pzhj 3680 3 dafter daft JJR cord-005646-xhx9pzhj 3680 4 51gmficautl 51gmficautl XX cord-005646-xhx9pzhj 3680 5 y y NNP cord-005646-xhx9pzhj 3680 6 a a DT cord-005646-xhx9pzhj 3680 7 - - HYPH cord-005646-xhx9pzhj 3680 8 ore ore NN cord-005646-xhx9pzhj 3680 9 ead~ ead~ CD cord-005646-xhx9pzhj 3680 10 other other JJ cord-005646-xhx9pzhj 3680 11 . . . cord-005646-xhx9pzhj 3681 1 Condusion condusion NN cord-005646-xhx9pzhj 3681 2 : : : cord-005646-xhx9pzhj 3682 1 L!a L!a NNP cord-005646-xhx9pzhj 3682 2 premature premature JJ cord-005646-xhx9pzhj 3682 3 mthats mthat NNS cord-005646-xhx9pzhj 3682 4 with with IN cord-005646-xhx9pzhj 3682 5 RDS RDS NNP cord-005646-xhx9pzhj 3682 6 treated treat VBN cord-005646-xhx9pzhj 3682 7 with with IN cord-005646-xhx9pzhj 3682 8 surfaaaat surfaaaat NN cord-005646-xhx9pzhj 3682 9 replacemeaat replacemeaat NN cord-005646-xhx9pzhj 3682 10 therapy therapy NN cord-005646-xhx9pzhj 3682 11 we -PRON- PRP cord-005646-xhx9pzhj 3682 12 observed observe VBD cord-005646-xhx9pzhj 3682 13 decrease decrease VBP cord-005646-xhx9pzhj 3682 14 m m NNP cord-005646-xhx9pzhj 3682 15 mc mc NNP cord-005646-xhx9pzhj 3682 16 ~ ~ NNP cord-005646-xhx9pzhj 3682 17 de de NNP cord-005646-xhx9pzhj 3682 18 ~ ~ NNP cord-005646-xhx9pzhj 3682 19 ce ce NNP cord-005646-xhx9pzhj 3682 20 of of IN cord-005646-xhx9pzhj 3682 21 tme'~m tme'~m NNP cord-005646-xhx9pzhj 3683 1 ~o ~o NNP cord-005646-xhx9pzhj 3683 2 ~ ~ NFP cord-005646-xhx9pzhj 3683 3 oraces orace NNS cord-005646-xhx9pzhj 3683 4 add add VBP cord-005646-xhx9pzhj 3683 5 de de NNP cord-005646-xhx9pzhj 3683 6 ~ ~ NFP cord-005646-xhx9pzhj 3683 7 th th XX cord-005646-xhx9pzhj 3683 8 ( ( -LRB- cord-005646-xhx9pzhj 3683 9 p<0.01 p<0.01 NNP cord-005646-xhx9pzhj 3683 10 and and CC cord-005646-xhx9pzhj 3683 11 p<0.05 p<0.05 NNP cord-005646-xhx9pzhj 3683 12 ) ) -RRB- cord-005646-xhx9pzhj 3683 13 , , , cord-005646-xhx9pzhj 3683 14 whe whe RB cord-005646-xhx9pzhj 3684 1 ~e ~e NNP cord-005646-xhx9pzhj 3685 1 ~s ~s NNP cord-005646-xhx9pzhj 3685 2 m m NNP cord-005646-xhx9pzhj 3685 3 othe~ othe~ NNP cord-005646-xhx9pzhj 3685 4 observed observe VBN cord-005646-xhx9pzhj 3685 5 variables variable NNS cord-005646-xhx9pzhj 3685 6 thee thee PRP cord-005646-xhx9pzhj 3685 7 was be VBD cord-005646-xhx9pzhj 3685 8 uo uo UH cord-005646-xhx9pzhj 3685 9 , , , cord-005646-xhx9pzhj 3685 10 igmfi igmfi NNP cord-005646-xhx9pzhj 3685 11 ~ ~ NFP cord-005646-xhx9pzhj 3685 12 t t NNP cord-005646-xhx9pzhj 3685 13 d~=ecce d~=ecce NNP cord-005646-xhx9pzhj 3685 14 Infectious infectious JJ cord-005646-xhx9pzhj 3685 15 complications complication NNS cord-005646-xhx9pzhj 3685 16 during during IN cord-005646-xhx9pzhj 3685 17 the the DT cord-005646-xhx9pzhj 3685 18 therapy therapy NN cord-005646-xhx9pzhj 3685 19 of of IN cord-005646-xhx9pzhj 3685 20 respiratory respiratory JJ cord-005646-xhx9pzhj 3685 21 insufficiency insufficiency NN cord-005646-xhx9pzhj 3685 22 in in IN cord-005646-xhx9pzhj 3685 23 neonates neonate NNS cord-005646-xhx9pzhj 3685 24 with with IN cord-005646-xhx9pzhj 3685 25 birth birth NN cord-005646-xhx9pzhj 3685 26 weight weight NN cord-005646-xhx9pzhj 3685 27 less less JJR cord-005646-xhx9pzhj 3685 28 than than IN cord-005646-xhx9pzhj 3685 29 1500 1500 CD cord-005646-xhx9pzhj 3685 30 g g NN cord-005646-xhx9pzhj 3685 31 in in IN cord-005646-xhx9pzhj 3685 32 the the DT cord-005646-xhx9pzhj 3685 33 course course NN cord-005646-xhx9pzhj 3685 34 of of IN cord-005646-xhx9pzhj 3685 35 3 3 CD cord-005646-xhx9pzhj 3685 36 yearsretrospective yearsretrospective NN cord-005646-xhx9pzhj 3685 37 study study NN cord-005646-xhx9pzhj 3685 38 . . . cord-005646-xhx9pzhj 3686 1 Zitek Zitek NNP cord-005646-xhx9pzhj 3686 2 Infants Infants NNP cord-005646-xhx9pzhj 3686 3 on on IN cord-005646-xhx9pzhj 3686 4 CMV CMV NNP cord-005646-xhx9pzhj 3686 5 , , , cord-005646-xhx9pzhj 3686 6 CPPV CPPV NNP cord-005646-xhx9pzhj 3686 7 , , , cord-005646-xhx9pzhj 3686 8 and and CC cord-005646-xhx9pzhj 3686 9 IMV IMV NNP cord-005646-xhx9pzhj 3686 10 were be VBD cord-005646-xhx9pzhj 3686 11 administered administer VBN cord-005646-xhx9pzhj 3686 12 EXOSURF EXOSURF NNP cord-005646-xhx9pzhj 3686 13 in in IN cord-005646-xhx9pzhj 3686 14 dose dose NN cord-005646-xhx9pzhj 3686 15 of of IN cord-005646-xhx9pzhj 3686 16 50 50 CD cord-005646-xhx9pzhj 3686 17 - - SYM cord-005646-xhx9pzhj 3686 18 60 60 CD cord-005646-xhx9pzhj 3686 19 mg mg NNP cord-005646-xhx9pzhj 3686 20 / / SYM cord-005646-xhx9pzhj 3686 21 kg kg NNS cord-005646-xhx9pzhj 3686 22 twice twice RB cord-005646-xhx9pzhj 3686 23 endotracheally endotracheally RB cord-005646-xhx9pzhj 3686 24 ( ( -LRB- cord-005646-xhx9pzhj 3686 25 see see VB cord-005646-xhx9pzhj 3686 26 Table table NN cord-005646-xhx9pzhj 3686 27 ) ) -RRB- cord-005646-xhx9pzhj 3686 28 . . . cord-005646-xhx9pzhj 3687 1 In in IN cord-005646-xhx9pzhj 3687 2 32 32 CD cord-005646-xhx9pzhj 3687 3 newborns newborn NNS cord-005646-xhx9pzhj 3687 4 ( ( -LRB- cord-005646-xhx9pzhj 3687 5 86.4 86.4 CD cord-005646-xhx9pzhj 3687 6 % % NN cord-005646-xhx9pzhj 3687 7 ) ) -RRB- cord-005646-xhx9pzhj 3687 8 2 2 CD cord-005646-xhx9pzhj 3687 9 hours hour NNS cord-005646-xhx9pzhj 3687 10 after after IN cord-005646-xhx9pzhj 3687 11 surfactant surfactant NN cord-005646-xhx9pzhj 3687 12 admin admin NN cord-005646-xhx9pzhj 3687 13 Fi02 Fi02 NNP cord-005646-xhx9pzhj 3687 14 value value NN cord-005646-xhx9pzhj 3687 15 decreased decrease VBN cord-005646-xhx9pzhj 3687 16 by by IN cord-005646-xhx9pzhj 3687 17 20.8 20.8 CD cord-005646-xhx9pzhj 3687 18 % % NN cord-005646-xhx9pzhj 3687 19 , , , cord-005646-xhx9pzhj 3687 20 and and CC cord-005646-xhx9pzhj 3687 21 after after IN cord-005646-xhx9pzhj 3687 22 6 6 CD cord-005646-xhx9pzhj 3687 23 hours hour NNS cord-005646-xhx9pzhj 3687 24 -by -by CD cord-005646-xhx9pzhj 3687 25 28.1 28.1 CD cord-005646-xhx9pzhj 3687 26 % % NN cord-005646-xhx9pzhj 3687 27 compared compare VBN cord-005646-xhx9pzhj 3687 28 with with IN cord-005646-xhx9pzhj 3687 29 initial initial JJ cord-005646-xhx9pzhj 3687 30 value value NN cord-005646-xhx9pzhj 3687 31 ; ; : cord-005646-xhx9pzhj 3687 32 PIP PIP NNP cord-005646-xhx9pzhj 3687 33 and and CC cord-005646-xhx9pzhj 3687 34 PEEP peep NN cord-005646-xhx9pzhj 3687 35 values value NNS cord-005646-xhx9pzhj 3687 36 decreased decrease VBD cord-005646-xhx9pzhj 3687 37 by by IN cord-005646-xhx9pzhj 3687 38 3 3 CD cord-005646-xhx9pzhj 3687 39 - - SYM cord-005646-xhx9pzhj 3687 40 5 5 CD cord-005646-xhx9pzhj 3687 41 cm cm NN cord-005646-xhx9pzhj 3687 42 H20 h20 NN cord-005646-xhx9pzhj 3687 43 and and CC cord-005646-xhx9pzhj 3687 44 1 1 CD cord-005646-xhx9pzhj 3687 45 - - SYM cord-005646-xhx9pzhj 3687 46 2 2 CD cord-005646-xhx9pzhj 3687 47 cm cm NN cord-005646-xhx9pzhj 3687 48 H20 h20 NN cord-005646-xhx9pzhj 3687 49 after after IN cord-005646-xhx9pzhj 3687 50 6 6 CD cord-005646-xhx9pzhj 3687 51 hours hour NNS cord-005646-xhx9pzhj 3687 52 , , , cord-005646-xhx9pzhj 3687 53 and and CC cord-005646-xhx9pzhj 3687 54 by by IN cord-005646-xhx9pzhj 3687 55 4 4 CD cord-005646-xhx9pzhj 3687 56 - - SYM cord-005646-xhx9pzhj 3687 57 7 7 CD cord-005646-xhx9pzhj 3687 58 cm cm NN cord-005646-xhx9pzhj 3687 59 H20 h20 NN cord-005646-xhx9pzhj 3687 60 and and CC cord-005646-xhx9pzhj 3687 61 2 2 CD cord-005646-xhx9pzhj 3687 62 - - SYM cord-005646-xhx9pzhj 3687 63 3 3 CD cord-005646-xhx9pzhj 3687 64 cm cm NN cord-005646-xhx9pzhj 3687 65 H20 h20 NN cord-005646-xhx9pzhj 3687 66 after after IN cord-005646-xhx9pzhj 3687 67 1 1 CD cord-005646-xhx9pzhj 3687 68 day day NN cord-005646-xhx9pzhj 3687 69 , , , cord-005646-xhx9pzhj 3687 70 respectively respectively RB cord-005646-xhx9pzhj 3687 71 accompanied accompany VBN cord-005646-xhx9pzhj 3687 72 by by IN cord-005646-xhx9pzhj 3687 73 mean mean JJ cord-005646-xhx9pzhj 3687 74 decrease decrease NN cord-005646-xhx9pzhj 3687 75 of of IN cord-005646-xhx9pzhj 3687 76 AaDO2 aado2 NN cord-005646-xhx9pzhj 3687 77 from from IN cord-005646-xhx9pzhj 3687 78 486,2 486,2 CD cord-005646-xhx9pzhj 3687 79 to to IN cord-005646-xhx9pzhj 3687 80 240.2 240.2 CD cord-005646-xhx9pzhj 3687 81 mmHg mmHg NNS cord-005646-xhx9pzhj 3687 82 , , , cord-005646-xhx9pzhj 3687 83 Qs Qs NNP cord-005646-xhx9pzhj 3687 84 / / SYM cord-005646-xhx9pzhj 3687 85 Qt Qt NNP cord-005646-xhx9pzhj 3687 86 decrease decrease NN cord-005646-xhx9pzhj 3687 87 from from IN cord-005646-xhx9pzhj 3687 88 24.9 24.9 CD cord-005646-xhx9pzhj 3687 89 to to IN cord-005646-xhx9pzhj 3687 90 13.2 13.2 CD cord-005646-xhx9pzhj 3687 91 % % NN cord-005646-xhx9pzhj 3687 92 ( ( -LRB- cord-005646-xhx9pzhj 3687 93 see see VB cord-005646-xhx9pzhj 3687 94 Table table NN cord-005646-xhx9pzhj 3687 95 ) ) -RRB- cord-005646-xhx9pzhj 3687 96 . . . cord-005646-xhx9pzhj 3688 1 Mean mean JJ cord-005646-xhx9pzhj 3688 2 time time NN cord-005646-xhx9pzhj 3688 3 of of IN cord-005646-xhx9pzhj 3688 4 CMV CMV NNP cord-005646-xhx9pzhj 3688 5 , , , cord-005646-xhx9pzhj 3688 6 CPPV CPPV NNP cord-005646-xhx9pzhj 3688 7 was be VBD cord-005646-xhx9pzhj 3688 8 7.8 7.8 CD cord-005646-xhx9pzhj 3688 9 days day NNS cord-005646-xhx9pzhj 3688 10 , , , cord-005646-xhx9pzhj 3688 11 IMV-14 IMV-14 NNP cord-005646-xhx9pzhj 3688 12 - - HYPH cord-005646-xhx9pzhj 3688 13 36 36 CD cord-005646-xhx9pzhj 3688 14 hours hour NNS cord-005646-xhx9pzhj 3688 15 , , , cord-005646-xhx9pzhj 3688 16 CPAP CPAP NNP cord-005646-xhx9pzhj 3688 17 -10 -10 NNP cord-005646-xhx9pzhj 3688 18 - - HYPH cord-005646-xhx9pzhj 3688 19 24 24 CD cord-005646-xhx9pzhj 3688 20 hours hour NNS cord-005646-xhx9pzhj 3688 21 . . . cord-005646-xhx9pzhj 3689 1 Respiratory respiratory JJ cord-005646-xhx9pzhj 3689 2 therapy therapy NN cord-005646-xhx9pzhj 3689 3 in in IN cord-005646-xhx9pzhj 3689 4 5 5 CD cord-005646-xhx9pzhj 3689 5 newborns newborn NNS cord-005646-xhx9pzhj 3689 6 ( ( -LRB- cord-005646-xhx9pzhj 3689 7 13.5 13.5 CD cord-005646-xhx9pzhj 3689 8 % % NN cord-005646-xhx9pzhj 3689 9 ) ) -RRB- cord-005646-xhx9pzhj 3689 10 was be VBD cord-005646-xhx9pzhj 3689 11 complicated complicate VBN cord-005646-xhx9pzhj 3689 12 by by IN cord-005646-xhx9pzhj 3689 13 pneumothorax pneumothorax NN cord-005646-xhx9pzhj 3689 14 ( ( -LRB- cord-005646-xhx9pzhj 3689 15 bilateral bilateral JJ cord-005646-xhx9pzhj 3689 16 -in -in SYM cord-005646-xhx9pzhj 3689 17 2 2 CD cord-005646-xhx9pzhj 3689 18 infants infant NNS cord-005646-xhx9pzhj 3690 1 Chorioangioma Chorioangioma NNP cord-005646-xhx9pzhj 3690 2 is be VBZ cord-005646-xhx9pzhj 3690 3 a a DT cord-005646-xhx9pzhj 3690 4 rela rela NNP cord-005646-xhx9pzhj 3690 5 ~ ~ NFP cord-005646-xhx9pzhj 3690 6 ively ively RB cord-005646-xhx9pzhj 3690 7 rare rare JJ cord-005646-xhx9pzhj 3690 8 placentaI placentaI NNP cord-005646-xhx9pzhj 3690 9 malformation malformation NN cord-005646-xhx9pzhj 3690 10 associated associate VBN cord-005646-xhx9pzhj 3690 11 with with IN cord-005646-xhx9pzhj 3690 12 considerable considerable JJ cord-005646-xhx9pzhj 3690 13 mortality mortality NN cord-005646-xhx9pzhj 3690 14 and and CC cord-005646-xhx9pzhj 3690 15 morbidity morbidity NN cord-005646-xhx9pzhj 3690 16 . . . cord-005646-xhx9pzhj 3691 1 A a DT cord-005646-xhx9pzhj 3691 2 chorioangioma chorioangioma NN cord-005646-xhx9pzhj 3691 3 can can MD cord-005646-xhx9pzhj 3691 4 be be VB cord-005646-xhx9pzhj 3691 5 regarded regard VBN cord-005646-xhx9pzhj 3691 6 as as IN cord-005646-xhx9pzhj 3691 7 an an DT cord-005646-xhx9pzhj 3691 8 arterio arterio NN cord-005646-xhx9pzhj 3691 9 - - HYPH cord-005646-xhx9pzhj 3691 10 venous venous JJ cord-005646-xhx9pzhj 3691 11 shunt shunt NN cord-005646-xhx9pzhj 3691 12 in in IN cord-005646-xhx9pzhj 3691 13 the the DT cord-005646-xhx9pzhj 3691 14 circulatory circulatory JJ cord-005646-xhx9pzhj 3691 15 system system NN cord-005646-xhx9pzhj 3691 16 of of IN cord-005646-xhx9pzhj 3691 17 the the DT cord-005646-xhx9pzhj 3691 18 fetus fetus NN cord-005646-xhx9pzhj 3691 19 . . . cord-005646-xhx9pzhj 3692 1 This this DT cord-005646-xhx9pzhj 3692 2 causes cause VBZ cord-005646-xhx9pzhj 3692 3 volume volume NN cord-005646-xhx9pzhj 3692 4 loading loading NN cord-005646-xhx9pzhj 3692 5 eventually eventually RB cord-005646-xhx9pzhj 3692 6 resulting result VBG cord-005646-xhx9pzhj 3692 7 in in IN cord-005646-xhx9pzhj 3692 8 cardiomegaly cardiomegaly JJ cord-005646-xhx9pzhj 3692 9 and and CC cord-005646-xhx9pzhj 3692 10 high high JJ cord-005646-xhx9pzhj 3692 11 output output NN cord-005646-xhx9pzhj 3692 12 cardiac cardiac NN cord-005646-xhx9pzhj 3692 13 failure failure NN cord-005646-xhx9pzhj 3692 14 . . . cord-005646-xhx9pzhj 3693 1 A a DT cord-005646-xhx9pzhj 3693 2 female female JJ cord-005646-xhx9pzhj 3693 3 neonate neonate NN cord-005646-xhx9pzhj 3693 4 ( ( -LRB- cord-005646-xhx9pzhj 3693 5 gest gest NNP cord-005646-xhx9pzhj 3693 6 age age NN cord-005646-xhx9pzhj 3693 7 40 40 CD cord-005646-xhx9pzhj 3693 8 wk wk NN cord-005646-xhx9pzhj 3693 9 , , , cord-005646-xhx9pzhj 3693 10 birth birth NN cord-005646-xhx9pzhj 3693 11 weight weight NN cord-005646-xhx9pzhj 3693 12 2290 2290 CD cord-005646-xhx9pzhj 3693 13 g g NN cord-005646-xhx9pzhj 3693 14 , , , cord-005646-xhx9pzhj 3693 15 -2.6 -2.6 NNP cord-005646-xhx9pzhj 3693 16 SD SD NNP cord-005646-xhx9pzhj 3693 17 ) ) -RRB- cord-005646-xhx9pzhj 3693 18 was be VBD cord-005646-xhx9pzhj 3693 19 born bear VBN cord-005646-xhx9pzhj 3693 20 with with IN cord-005646-xhx9pzhj 3693 21 an an DT cord-005646-xhx9pzhj 3693 22 apgar apgar JJ cord-005646-xhx9pzhj 3693 23 score score NN cord-005646-xhx9pzhj 3693 24 of of IN cord-005646-xhx9pzhj 3693 25 4 4 CD cord-005646-xhx9pzhj 3693 26 and and CC cord-005646-xhx9pzhj 3693 27 7 7 CD cord-005646-xhx9pzhj 3693 28 after after IN cord-005646-xhx9pzhj 3693 29 1 1 CD cord-005646-xhx9pzhj 3693 30 and and CC cord-005646-xhx9pzhj 3693 31 5 5 CD cord-005646-xhx9pzhj 3693 32 rain rain NN cord-005646-xhx9pzhj 3693 33 respectively respectively RB cord-005646-xhx9pzhj 3693 34 . . . cord-005646-xhx9pzhj 3694 1 The the DT cord-005646-xhx9pzhj 3694 2 placenta placenta NN cord-005646-xhx9pzhj 3694 3 showed show VBD cord-005646-xhx9pzhj 3694 4 multiple multiple JJ cord-005646-xhx9pzhj 3694 5 chorioangioma chorioangioma NN cord-005646-xhx9pzhj 3694 6 . . . cord-005646-xhx9pzhj 3695 1 Ultrasound ultrasound NN cord-005646-xhx9pzhj 3695 2 of of IN cord-005646-xhx9pzhj 3695 3 the the DT cord-005646-xhx9pzhj 3695 4 heart heart NN cord-005646-xhx9pzhj 3695 5 showed show VBD cord-005646-xhx9pzhj 3695 6 a a DT cord-005646-xhx9pzhj 3695 7 hypertrophic hypertrophic JJ cord-005646-xhx9pzhj 3695 8 cardiomyopathy cardiomyopathy NN cord-005646-xhx9pzhj 3695 9 . . . cord-005646-xhx9pzhj 3696 1 She -PRON- PRP cord-005646-xhx9pzhj 3696 2 developed develop VBD cord-005646-xhx9pzhj 3696 3 severe severe JJ cord-005646-xhx9pzhj 3696 4 hypertension hypertension NN cord-005646-xhx9pzhj 3696 5 ( ( -LRB- cord-005646-xhx9pzhj 3696 6 100/70 100/70 CD cord-005646-xhx9pzhj 3696 7 mm mm CD cord-005646-xhx9pzhj 3696 8 Hg Hg NNP cord-005646-xhx9pzhj 3696 9 ) ) -RRB- cord-005646-xhx9pzhj 3696 10 , , , cord-005646-xhx9pzhj 3696 11 treated treat VBN cord-005646-xhx9pzhj 3696 12 with with IN cord-005646-xhx9pzhj 3696 13 nitroglycerine nitroglycerine NN cord-005646-xhx9pzhj 3696 14 and and CC cord-005646-xhx9pzhj 3696 15 nitropruside nitropruside NN cord-005646-xhx9pzhj 3696 16 . . . cord-005646-xhx9pzhj 3697 1 Finally finally RB cord-005646-xhx9pzhj 3697 2 blood blood NN cord-005646-xhx9pzhj 3697 3 pressure pressure NN cord-005646-xhx9pzhj 3697 4 decreased decrease VBD cord-005646-xhx9pzhj 3697 5 when when WRB cord-005646-xhx9pzhj 3697 6 enalaprillic enalaprillic JJ cord-005646-xhx9pzhj 3697 7 acid acid NN cord-005646-xhx9pzhj 3697 8 was be VBD cord-005646-xhx9pzhj 3697 9 given give VBN cord-005646-xhx9pzhj 3697 10 ( ( -LRB- cord-005646-xhx9pzhj 3697 11 0.15 0.15 CD cord-005646-xhx9pzhj 3697 12 mg.kg4 mg.kg4 NNS cord-005646-xhx9pzhj 3697 13 ) ) -RRB- cord-005646-xhx9pzhj 3697 14 . . . cord-005646-xhx9pzhj 3698 1 We -PRON- PRP cord-005646-xhx9pzhj 3698 2 measuered measuere VBD cord-005646-xhx9pzhj 3698 3 the the DT cord-005646-xhx9pzhj 3698 4 activity activity NN cord-005646-xhx9pzhj 3698 5 of of IN cord-005646-xhx9pzhj 3698 6 the the DT cord-005646-xhx9pzhj 3698 7 renin renin NN cord-005646-xhx9pzhj 3698 8 - - HYPH cord-005646-xhx9pzhj 3698 9 angiotensinsystem angiotensinsystem NNP cord-005646-xhx9pzhj 3698 10 . . . cord-005646-xhx9pzhj 3699 1 An an DT cord-005646-xhx9pzhj 3699 2 elevation elevation NN cord-005646-xhx9pzhj 3699 3 in in IN cord-005646-xhx9pzhj 3699 4 renin renin NN cord-005646-xhx9pzhj 3699 5 - - HYPH cord-005646-xhx9pzhj 3699 6 angiotensin angiotensin NN cord-005646-xhx9pzhj 3699 7 system system NN cord-005646-xhx9pzhj 3699 8 is be VBZ cord-005646-xhx9pzhj 3699 9 shown show VBN cord-005646-xhx9pzhj 3699 10 probably probably RB cord-005646-xhx9pzhj 3699 11 to to TO cord-005646-xhx9pzhj 3699 12 compensate compensate VB cord-005646-xhx9pzhj 3699 13 for for IN cord-005646-xhx9pzhj 3699 14 the the DT cord-005646-xhx9pzhj 3699 15 low low JJ cord-005646-xhx9pzhj 3699 16 resistance resistance NN cord-005646-xhx9pzhj 3699 17 circulation circulation NN cord-005646-xhx9pzhj 3699 18 before before IN cord-005646-xhx9pzhj 3699 19 birth birth NN cord-005646-xhx9pzhj 3699 20 , , , cord-005646-xhx9pzhj 3699 21 Hypothesis hypothesis NN cord-005646-xhx9pzhj 3699 22 : : : cord-005646-xhx9pzhj 3699 23 The the DT cord-005646-xhx9pzhj 3699 24 instantaneous instantaneous JJ cord-005646-xhx9pzhj 3699 25 cut cut NN cord-005646-xhx9pzhj 3699 26 off off RP cord-005646-xhx9pzhj 3699 27 of of IN cord-005646-xhx9pzhj 3699 28 a a DT cord-005646-xhx9pzhj 3699 29 large large JJ cord-005646-xhx9pzhj 3699 30 arteriovenous arteriovenous JJ cord-005646-xhx9pzhj 3699 31 shunt shunt NN cord-005646-xhx9pzhj 3699 32 did do VBD cord-005646-xhx9pzhj 3699 33 not not RB cord-005646-xhx9pzhj 3699 34 result result VB cord-005646-xhx9pzhj 3699 35 in in IN cord-005646-xhx9pzhj 3699 36 a a DT cord-005646-xhx9pzhj 3699 37 fast fast JJ cord-005646-xhx9pzhj 3699 38 downregulation downregulation NN cord-005646-xhx9pzhj 3699 39 of of IN cord-005646-xhx9pzhj 3699 40 the the DT cord-005646-xhx9pzhj 3699 41 renin renin NN cord-005646-xhx9pzhj 3699 42 - - HYPH cord-005646-xhx9pzhj 3699 43 angiotensin angiotensin NN cord-005646-xhx9pzhj 3699 44 system system NN cord-005646-xhx9pzhj 3699 45 resulting result VBG cord-005646-xhx9pzhj 3699 46 in in IN cord-005646-xhx9pzhj 3699 47 hypertension hypertension NN cord-005646-xhx9pzhj 3699 48 . . . cord-005646-xhx9pzhj 3700 1 Hypertension hypertension NN cord-005646-xhx9pzhj 3700 2 should should MD cord-005646-xhx9pzhj 3700 3 be be VB cord-005646-xhx9pzhj 3700 4 added add VBN cord-005646-xhx9pzhj 3700 5 to to IN cord-005646-xhx9pzhj 3700 6 the the DT cord-005646-xhx9pzhj 3700 7 list list NN cord-005646-xhx9pzhj 3700 8 of of IN cord-005646-xhx9pzhj 3700 9 complications complication NNS cord-005646-xhx9pzhj 3700 10 of of IN cord-005646-xhx9pzhj 3700 11 chorioangioma chorioangioma NN cord-005646-xhx9pzhj 3700 12 of of IN cord-005646-xhx9pzhj 3700 13 the the DT cord-005646-xhx9pzhj 3700 14 placenta placenta NN cord-005646-xhx9pzhj 3700 15 . . . cord-005646-xhx9pzhj 3701 1 The the DT cord-005646-xhx9pzhj 3701 2 authors author NNS cord-005646-xhx9pzhj 3701 3 studied study VBD cord-005646-xhx9pzhj 3701 4 75 75 CD cord-005646-xhx9pzhj 3701 5 cases case NNS cord-005646-xhx9pzhj 3701 6 of of IN cord-005646-xhx9pzhj 3701 7 children child NNS cord-005646-xhx9pzhj 3701 8 's 's POS cord-005646-xhx9pzhj 3701 9 septicemia septicemia NN cord-005646-xhx9pzhj 3701 10 with with IN cord-005646-xhx9pzhj 3701 11 blood blood NN cord-005646-xhx9pzhj 3701 12 culture culture NN cord-005646-xhx9pzhj 3701 13 yielding yield VBG cord-005646-xhx9pzhj 3701 14 Staphylocucetts Staphylocucetts NNP cord-005646-xhx9pzhj 3701 15 aurens auren NNS cord-005646-xhx9pzhj 3701 16 . . . cord-005646-xhx9pzhj 3702 1 The the DT cord-005646-xhx9pzhj 3702 2 age age NN cord-005646-xhx9pzhj 3702 3 of of IN cord-005646-xhx9pzhj 3702 4 patients patient NNS cord-005646-xhx9pzhj 3702 5 varied varied JJ cord-005646-xhx9pzhj 3702 6 from from IN cord-005646-xhx9pzhj 3702 7 2 2 CD cord-005646-xhx9pzhj 3702 8 months month NNS cord-005646-xhx9pzhj 3702 9 to to IN cord-005646-xhx9pzhj 3702 10 15 15 CD cord-005646-xhx9pzhj 3702 11 years year NNS cord-005646-xhx9pzhj 3702 12 ( ( -LRB- cord-005646-xhx9pzhj 3702 13 51,3 51,3 CD cord-005646-xhx9pzhj 3702 14 % % NN cord-005646-xhx9pzhj 3702 15 from from IN cord-005646-xhx9pzhj 3702 16 3 3 CD cord-005646-xhx9pzhj 3702 17 years year NNS cord-005646-xhx9pzhj 3702 18 downward downward RB cord-005646-xhx9pzhj 3702 19 ) ) -RRB- cord-005646-xhx9pzhj 3702 20 , , , cord-005646-xhx9pzhj 3702 21 74 74 CD cord-005646-xhx9pzhj 3702 22 % % NN cord-005646-xhx9pzhj 3702 23 of of IN cord-005646-xhx9pzhj 3702 24 the the DT cord-005646-xhx9pzhj 3702 25 children child NNS cord-005646-xhx9pzhj 3702 26 caught catch VBD cord-005646-xhx9pzhj 3702 27 their -PRON- PRP$ cord-005646-xhx9pzhj 3702 28 disease disease NN cord-005646-xhx9pzhj 3702 29 in in IN cord-005646-xhx9pzhj 3702 30 the the DT cord-005646-xhx9pzhj 3702 31 hot hot JJ cord-005646-xhx9pzhj 3702 32 season season NN cord-005646-xhx9pzhj 3702 33 ( ( -LRB- cord-005646-xhx9pzhj 3702 34 May May NNP cord-005646-xhx9pzhj 3702 35 to to IN cord-005646-xhx9pzhj 3702 36 October October NNP cord-005646-xhx9pzhj 3702 37 ) ) -RRB- cord-005646-xhx9pzhj 3702 38 . . . cord-005646-xhx9pzhj 3703 1 The the DT cord-005646-xhx9pzhj 3703 2 deaths death NNS cord-005646-xhx9pzhj 3703 3 also also RB cord-005646-xhx9pzhj 3703 4 occured occur VBD cord-005646-xhx9pzhj 3703 5 in in IN cord-005646-xhx9pzhj 3703 6 this this DT cord-005646-xhx9pzhj 3703 7 season season NN cord-005646-xhx9pzhj 3703 8 : : : cord-005646-xhx9pzhj 3703 9 87,5 87,5 CD cord-005646-xhx9pzhj 3703 10 % % NN cord-005646-xhx9pzhj 3703 11 ( ( -LRB- cord-005646-xhx9pzhj 3703 12 21/24 21/24 CD cord-005646-xhx9pzhj 3703 13 ) ) -RRB- cord-005646-xhx9pzhj 3703 14 . . . cord-005646-xhx9pzhj 3704 1 Following follow VBG cord-005646-xhx9pzhj 3704 2 were be VBD cord-005646-xhx9pzhj 3704 3 the the DT cord-005646-xhx9pzhj 3704 4 anatomo anatomo JJ cord-005646-xhx9pzhj 3704 5 - - HYPH cord-005646-xhx9pzhj 3704 6 dinical dinical JJ cord-005646-xhx9pzhj 3704 7 lesions lesion NNS cord-005646-xhx9pzhj 3704 8 . . . cord-005646-xhx9pzhj 3705 1 -Skin -Skin NFP cord-005646-xhx9pzhj 3706 1 42 42 CD cord-005646-xhx9pzhj 3706 2 % % NN cord-005646-xhx9pzhj 3706 3 , , , cord-005646-xhx9pzhj 3706 4 muscle muscle NN cord-005646-xhx9pzhj 3706 5 60,0 60,0 CD cord-005646-xhx9pzhj 3706 6 % % NN cord-005646-xhx9pzhj 3706 7 , , , cord-005646-xhx9pzhj 3706 8 bone bone NN cord-005646-xhx9pzhj 3706 9 21,3 21,3 CD cord-005646-xhx9pzhj 3706 10 % % NN cord-005646-xhx9pzhj 3706 11 , , , cord-005646-xhx9pzhj 3706 12 Joint Joint NNP cord-005646-xhx9pzhj 3706 13 9.3 9.3 CD cord-005646-xhx9pzhj 3706 14 % % NN cord-005646-xhx9pzhj 3706 15 . . . cord-005646-xhx9pzhj 3707 1 -Viscera -viscera NN cord-005646-xhx9pzhj 3707 2 : : : cord-005646-xhx9pzhj 3708 1 lung lung NN cord-005646-xhx9pzhj 3708 2 50 50 CD cord-005646-xhx9pzhj 3708 3 % % NN cord-005646-xhx9pzhj 3708 4 , , , cord-005646-xhx9pzhj 3708 5 heart heart NN cord-005646-xhx9pzhj 3708 6 33.3 33.3 CD cord-005646-xhx9pzhj 3708 7 % % NN cord-005646-xhx9pzhj 3708 8 , , , cord-005646-xhx9pzhj 3708 9 cerebrum cerebrum NN cord-005646-xhx9pzhj 3708 10 22.6 22.6 CD cord-005646-xhx9pzhj 3708 11 % % NN cord-005646-xhx9pzhj 3708 12 , , , cord-005646-xhx9pzhj 3708 13 kidney kidney NN cord-005646-xhx9pzhj 3708 14 60.6 60.6 CD cord-005646-xhx9pzhj 3708 15 % % NN cord-005646-xhx9pzhj 3708 16 , , , cord-005646-xhx9pzhj 3708 17 fiver fiver NN cord-005646-xhx9pzhj 3708 18 17,3 17,3 CD cord-005646-xhx9pzhj 3708 19 % % NN cord-005646-xhx9pzhj 3708 20 . . . cord-005646-xhx9pzhj 3709 1 -Simple -Simple . cord-005646-xhx9pzhj 3710 1 lesion lesion NN cord-005646-xhx9pzhj 3710 2 skin skin NN cord-005646-xhx9pzhj 3710 3 - - HYPH cord-005646-xhx9pzhj 3710 4 muscle muscle NN cord-005646-xhx9pzhj 3710 5 - - HYPH cord-005646-xhx9pzhj 3710 6 bone bone NN cord-005646-xhx9pzhj 3710 7 joint joint NN cord-005646-xhx9pzhj 3710 8 : : : cord-005646-xhx9pzhj 3710 9 12 12 CD cord-005646-xhx9pzhj 3710 10 % % NN cord-005646-xhx9pzhj 3710 11 , , , cord-005646-xhx9pzhj 3710 12 no no DT cord-005646-xhx9pzhj 3710 13 death death NN cord-005646-xhx9pzhj 3710 14 in in IN cord-005646-xhx9pzhj 3710 15 this this DT cord-005646-xhx9pzhj 3710 16 group group NN cord-005646-xhx9pzhj 3710 17 . . . cord-005646-xhx9pzhj 3711 1 The the DT cord-005646-xhx9pzhj 3711 2 concomitant concomitant JJ cord-005646-xhx9pzhj 3711 3 lesions lesion NNS cord-005646-xhx9pzhj 3711 4 of of IN cord-005646-xhx9pzhj 3711 5 the the DT cord-005646-xhx9pzhj 3711 6 soft soft JJ cord-005646-xhx9pzhj 3711 7 tissue tissue NN cord-005646-xhx9pzhj 3711 8 , , , cord-005646-xhx9pzhj 3711 9 bone bone NN cord-005646-xhx9pzhj 3711 10 - - HYPH cord-005646-xhx9pzhj 3711 11 joint joint NN cord-005646-xhx9pzhj 3711 12 and and CC cord-005646-xhx9pzhj 3711 13 viscera viscera NNS cord-005646-xhx9pzhj 3711 14 : : : cord-005646-xhx9pzhj 3711 15 34 34 CD cord-005646-xhx9pzhj 3711 16 % % NN cord-005646-xhx9pzhj 3711 17 with with IN cord-005646-xhx9pzhj 3711 18 one one CD cord-005646-xhx9pzhj 3711 19 viscera viscera NN cord-005646-xhx9pzhj 3711 20 , , , cord-005646-xhx9pzhj 3711 21 26 26 CD cord-005646-xhx9pzhj 3711 22 % % NN cord-005646-xhx9pzhj 3711 23 with with IN cord-005646-xhx9pzhj 3711 24 two two CD cord-005646-xhx9pzhj 3711 25 viscera viscera NNS cord-005646-xhx9pzhj 3711 26 , , , cord-005646-xhx9pzhj 3711 27 18 18 CD cord-005646-xhx9pzhj 3711 28 % % NN cord-005646-xhx9pzhj 3711 29 with with IN cord-005646-xhx9pzhj 3711 30 three three CD cord-005646-xhx9pzhj 3711 31 viscera viscera NNS cord-005646-xhx9pzhj 3711 32 and and CC cord-005646-xhx9pzhj 3711 33 9 9 CD cord-005646-xhx9pzhj 3711 34 % % NN cord-005646-xhx9pzhj 3711 35 with with IN cord-005646-xhx9pzhj 3711 36 four four CD cord-005646-xhx9pzhj 3711 37 viscera viscera NNS cord-005646-xhx9pzhj 3711 38 . . . cord-005646-xhx9pzhj 3712 1 -Bone -bone NN cord-005646-xhx9pzhj 3713 1 lesion lesion NN cord-005646-xhx9pzhj 3713 2 : : : cord-005646-xhx9pzhj 3713 3 Mainly mainly RB cord-005646-xhx9pzhj 3713 4 on on IN cord-005646-xhx9pzhj 3713 5 the the DT cord-005646-xhx9pzhj 3713 6 long long JJ cord-005646-xhx9pzhj 3713 7 bones bone NNS cord-005646-xhx9pzhj 3713 8 ( ( -LRB- cord-005646-xhx9pzhj 3713 9 50 50 CD cord-005646-xhx9pzhj 3713 10 % % NN cord-005646-xhx9pzhj 3713 11 on on IN cord-005646-xhx9pzhj 3713 12 the the DT cord-005646-xhx9pzhj 3713 13 tibia tibia NN cord-005646-xhx9pzhj 3713 14 , , , cord-005646-xhx9pzhj 3713 15 25 25 CD cord-005646-xhx9pzhj 3713 16 % % NN cord-005646-xhx9pzhj 3713 17 on on IN cord-005646-xhx9pzhj 3713 18 the the DT cord-005646-xhx9pzhj 3713 19 femur femur NN cord-005646-xhx9pzhj 3713 20 , , , cord-005646-xhx9pzhj 3713 21 the the DT cord-005646-xhx9pzhj 3713 22 remainder remainder NN cord-005646-xhx9pzhj 3713 23 being be VBG cord-005646-xhx9pzhj 3713 24 the the DT cord-005646-xhx9pzhj 3713 25 mandible mandible NN cord-005646-xhx9pzhj 3713 26 ( ( -LRB- cord-005646-xhx9pzhj 3713 27 3 3 CD cord-005646-xhx9pzhj 3713 28 ) ) -RRB- cord-005646-xhx9pzhj 3713 29 and and CC cord-005646-xhx9pzhj 3713 30 the the DT cord-005646-xhx9pzhj 3713 31 humerus humerus NNP cord-005646-xhx9pzhj 3713 32 ) ) -RRB- cord-005646-xhx9pzhj 3713 33 , , . cord-005646-xhx9pzhj 3714 1 inflammation inflammation NN cord-005646-xhx9pzhj 3714 2 of of IN cord-005646-xhx9pzhj 3714 3 ' ' '' cord-005646-xhx9pzhj 3714 4 the the DT cord-005646-xhx9pzhj 3714 5 hip hip NN cord-005646-xhx9pzhj 3714 6 joint joint NN cord-005646-xhx9pzhj 3714 7 was be VBD cord-005646-xhx9pzhj 3714 8 the the DT cord-005646-xhx9pzhj 3714 9 main main JJ cord-005646-xhx9pzhj 3714 10 one one NN cord-005646-xhx9pzhj 3714 11 . . . cord-005646-xhx9pzhj 3715 1 -I -I NNP cord-005646-xhx9pzhj 3715 2 , , , cord-005646-xhx9pzhj 3715 3 ung ung NN cord-005646-xhx9pzhj 3715 4 lesion lesion NN cord-005646-xhx9pzhj 3715 5 had have VBD cord-005646-xhx9pzhj 3715 6 forms form NNS cord-005646-xhx9pzhj 3715 7 pneumatocele pneumatocele NNP cord-005646-xhx9pzhj 3715 8 ( ( -LRB- cord-005646-xhx9pzhj 3715 9 4 4 CD cord-005646-xhx9pzhj 3715 10 cases case NNS cord-005646-xhx9pzhj 3715 11 ) ) -RRB- cord-005646-xhx9pzhj 3715 12 , , , cord-005646-xhx9pzhj 3715 13 bronchopneumonia bronchopneumonia NN cord-005646-xhx9pzhj 3715 14 ( ( -LRB- cord-005646-xhx9pzhj 3715 15 6 6 CD cord-005646-xhx9pzhj 3715 16 cases case NNS cord-005646-xhx9pzhj 3715 17 ) ) -RRB- cord-005646-xhx9pzhj 3715 18 , , , cord-005646-xhx9pzhj 3715 19 pleural pleural JJ cord-005646-xhx9pzhj 3715 20 effusion effusion NN cord-005646-xhx9pzhj 3715 21 ( ( -LRB- cord-005646-xhx9pzhj 3715 22 7 7 CD cord-005646-xhx9pzhj 3715 23 cases case NNS cord-005646-xhx9pzhj 3715 24 ) ) -RRB- cord-005646-xhx9pzhj 3715 25 , , , cord-005646-xhx9pzhj 3715 26 multimicroabcess multimicroabcess NN cord-005646-xhx9pzhj 3715 27 bursting burst VBG cord-005646-xhx9pzhj 3715 28 into into IN cord-005646-xhx9pzhj 3715 29 the the DT cord-005646-xhx9pzhj 3715 30 pleura pleura NN cord-005646-xhx9pzhj 3715 31 ( ( -LRB- cord-005646-xhx9pzhj 3715 32 8 8 CD cord-005646-xhx9pzhj 3715 33 cases case NNS cord-005646-xhx9pzhj 3715 34 ) ) -RRB- cord-005646-xhx9pzhj 3715 35 , , , cord-005646-xhx9pzhj 3715 36 most most JJS cord-005646-xhx9pzhj 3715 37 multimicroabcesses multimicroabcesse NNS cord-005646-xhx9pzhj 3715 38 were be VBD cord-005646-xhx9pzhj 3715 39 lethal lethal JJ cord-005646-xhx9pzhj 3715 40 : : : cord-005646-xhx9pzhj 3715 41 20/22 20/22 CD cord-005646-xhx9pzhj 3715 42 ( ( -LRB- cord-005646-xhx9pzhj 3715 43 90,9 90,9 CD cord-005646-xhx9pzhj 3715 44 % % NN cord-005646-xhx9pzhj 3715 45 ) ) -RRB- cord-005646-xhx9pzhj 3715 46 , , . cord-005646-xhx9pzhj 3716 1 -Heart -Heart NNS cord-005646-xhx9pzhj 3716 2 : : : cord-005646-xhx9pzhj 3716 3 all all DT cord-005646-xhx9pzhj 3716 4 thethreelay thethreelay NNP cord-005646-xhx9pzhj 3716 5 ~ ~ NFP cord-005646-xhx9pzhj 3716 6 rs rs NN cord-005646-xhx9pzhj 3716 7 got get VBD cord-005646-xhx9pzhj 3716 8 le@~r~ le@~r~ NNS cord-005646-xhx9pzhj 3716 9 , , , cord-005646-xhx9pzhj 3716 10 20 20 CD cord-005646-xhx9pzhj 3716 11 % % NN cord-005646-xhx9pzhj 3716 12 had have VBD cord-005646-xhx9pzhj 3716 13 2 2 CD cord-005646-xhx9pzhj 3716 14 or or CC cord-005646-xhx9pzhj 3716 15 3 3 CD cord-005646-xhx9pzhj 3716 16 layers layer NNS cord-005646-xhx9pzhj 3716 17 aLrected aLrected NNP cord-005646-xhx9pzhj 3716 18 and and CC cord-005646-xhx9pzhj 3716 19 death death NN cord-005646-xhx9pzhj 3716 20 ensued ensue VBD cord-005646-xhx9pzhj 3716 21 . . . cord-005646-xhx9pzhj 3717 1 -Cerebrum -Cerebrum VBZ cord-005646-xhx9pzhj 3717 2 : : : cord-005646-xhx9pzhj 3717 3 the the DT cord-005646-xhx9pzhj 3717 4 meninges meninge NNS cord-005646-xhx9pzhj 3717 5 had have VBD cord-005646-xhx9pzhj 3717 6 three three CD cord-005646-xhx9pzhj 3717 7 forms form NNS cord-005646-xhx9pzhj 3717 8 of of IN cord-005646-xhx9pzhj 3717 9 lesions lesion NNS cord-005646-xhx9pzhj 3717 10 purulent purulent JJ cord-005646-xhx9pzhj 3717 11 meningitis meningitis NN cord-005646-xhx9pzhj 3717 12 ( ( -LRB- cord-005646-xhx9pzhj 3717 13 13 13 CD cord-005646-xhx9pzhj 3717 14 cases case NNS cord-005646-xhx9pzhj 3717 15 ) ) -RRB- cord-005646-xhx9pzhj 3717 16 , , , cord-005646-xhx9pzhj 3717 17 obturafing obturafing NNP cord-005646-xhx9pzhj 3717 18 embolns emboln NNS cord-005646-xhx9pzhj 3717 19 of of IN cord-005646-xhx9pzhj 3717 20 brain brain NN cord-005646-xhx9pzhj 3717 21 vessels vessel NNS cord-005646-xhx9pzhj 3717 22 ( ( -LRB- cord-005646-xhx9pzhj 3717 23 2 2 CD cord-005646-xhx9pzhj 3717 24 cases case NNS cord-005646-xhx9pzhj 3717 25 ) ) -RRB- cord-005646-xhx9pzhj 3717 26 and and CC cord-005646-xhx9pzhj 3717 27 cerebral cerebral JJ cord-005646-xhx9pzhj 3717 28 abcess abcess NN cord-005646-xhx9pzhj 3717 29 ( ( -LRB- cord-005646-xhx9pzhj 3717 30 one one CD cord-005646-xhx9pzhj 3717 31 case case NN cord-005646-xhx9pzhj 3717 32 ) ) -RRB- cord-005646-xhx9pzhj 3717 33 . . . cord-005646-xhx9pzhj 3718 1 The the DT cord-005646-xhx9pzhj 3718 2 characteristic characteristic JJ cord-005646-xhx9pzhj 3718 3 clinical clinical JJ cord-005646-xhx9pzhj 3718 4 sign sign NN cord-005646-xhx9pzhj 3718 5 was be VBD cord-005646-xhx9pzhj 3718 6 paralysis paralysis NN cord-005646-xhx9pzhj 3718 7 and and CC cord-005646-xhx9pzhj 3718 8 meningismus meningismus NNP cord-005646-xhx9pzhj 3718 9 , , , cord-005646-xhx9pzhj 3718 10 phlebothrombosis phlebothrombosis NNP cord-005646-xhx9pzhj 3718 11 of of IN cord-005646-xhx9pzhj 3718 12 eavcrnous eavcrnous NNP cord-005646-xhx9pzhj 3718 13 finus finus NNP cord-005646-xhx9pzhj 3718 14 ( ( -LRB- cord-005646-xhx9pzhj 3718 15 13 13 CD cord-005646-xhx9pzhj 3718 16 cases)was cases)was NNP cord-005646-xhx9pzhj 3719 1 mually mually RB cord-005646-xhx9pzhj 3719 2 ther ther NNP cord-005646-xhx9pzhj 3719 3 ~ ~ NFP cord-005646-xhx9pzhj 3719 4 sultofalxil sultofalxil NNP cord-005646-xhx9pzhj 3719 5 vdfi vdfi NNP cord-005646-xhx9pzhj 3719 6 : : : cord-005646-xhx9pzhj 3720 1 h h NNP cord-005646-xhx9pzhj 3720 2 burst burst VBD cord-005646-xhx9pzhj 3721 1 There there EX cord-005646-xhx9pzhj 3721 2 were be VBD cord-005646-xhx9pzhj 3721 3 6 6 CD cord-005646-xhx9pzhj 3721 4 cases case NNS cord-005646-xhx9pzhj 3721 5 of of IN cord-005646-xhx9pzhj 3721 6 death death NN cord-005646-xhx9pzhj 3721 7 with with IN cord-005646-xhx9pzhj 3721 8 lesion lesion NN cord-005646-xhx9pzhj 3721 9 of of IN cord-005646-xhx9pzhj 3721 10 the the DT cord-005646-xhx9pzhj 3721 11 meninges meninge NNS cord-005646-xhx9pzhj 3721 12 and and CC cord-005646-xhx9pzhj 3721 13 2 2 CD cord-005646-xhx9pzhj 3721 14 cases case NNS cord-005646-xhx9pzhj 3721 15 of of IN cord-005646-xhx9pzhj 3721 16 obturating obturating NN cord-005646-xhx9pzhj 3721 17 embolns emboln NNS cord-005646-xhx9pzhj 3721 18 of of IN cord-005646-xhx9pzhj 3721 19 brain brain NN cord-005646-xhx9pzhj 3721 20 vessels vessel NNS cord-005646-xhx9pzhj 3721 21 . . . cord-005646-xhx9pzhj 3722 1 -The -the DT cord-005646-xhx9pzhj 3722 2 main main JJ cord-005646-xhx9pzhj 3722 3 sign sign NN cord-005646-xhx9pzhj 3722 4 of of IN cord-005646-xhx9pzhj 3722 5 lesion lesion NN cord-005646-xhx9pzhj 3722 6 of of IN cord-005646-xhx9pzhj 3722 7 the the DT cord-005646-xhx9pzhj 3722 8 kidney kidney NN cord-005646-xhx9pzhj 3722 9 was be VBD cord-005646-xhx9pzhj 3722 10 a a DT cord-005646-xhx9pzhj 3722 11 change change NN cord-005646-xhx9pzhj 3722 12 in in IN cord-005646-xhx9pzhj 3722 13 the the DT cord-005646-xhx9pzhj 3722 14 components component NNS cord-005646-xhx9pzhj 3722 15 of of IN cord-005646-xhx9pzhj 3722 16 urine urine NN cord-005646-xhx9pzhj 3722 17 : : : cord-005646-xhx9pzhj 3722 18 60 60 CD cord-005646-xhx9pzhj 3722 19 % % NN cord-005646-xhx9pzhj 3722 20 got get VBD cord-005646-xhx9pzhj 3722 21 proteinuria proteinuria NN cord-005646-xhx9pzhj 3722 22 , , , cord-005646-xhx9pzhj 3722 23 75 75 CD cord-005646-xhx9pzhj 3722 24 % % NN cord-005646-xhx9pzhj 3722 25 had have VBD cord-005646-xhx9pzhj 3722 26 leucocytes leucocyte NNS cord-005646-xhx9pzhj 3722 27 in in IN cord-005646-xhx9pzhj 3722 28 their -PRON- PRP$ cord-005646-xhx9pzhj 3722 29 urine urine NN cord-005646-xhx9pzhj 3722 30 , , , cord-005646-xhx9pzhj 3722 31 42 42 CD cord-005646-xhx9pzhj 3722 32 % % NN cord-005646-xhx9pzhj 3722 33 had have VBD cord-005646-xhx9pzhj 3722 34 erythrocytes erythrocyte NNS cord-005646-xhx9pzhj 3722 35 in in IN cord-005646-xhx9pzhj 3722 36 their -PRON- PRP$ cord-005646-xhx9pzhj 3722 37 urine urine NN cord-005646-xhx9pzhj 3722 38 , , , cord-005646-xhx9pzhj 3722 39 the the DT cord-005646-xhx9pzhj 3722 40 urea urea NN cord-005646-xhx9pzhj 3722 41 in in IN cord-005646-xhx9pzhj 3722 42 their -PRON- PRP$ cord-005646-xhx9pzhj 3722 43 blood blood NN cord-005646-xhx9pzhj 3722 44 increased increase VBD cord-005646-xhx9pzhj 3722 45 ( ( -LRB- cord-005646-xhx9pzhj 3722 46 over over IN cord-005646-xhx9pzhj 3722 47 60rag% 60rag% CD cord-005646-xhx9pzhj 3722 48 ) ) -RRB- cord-005646-xhx9pzhj 3722 49 in in IN cord-005646-xhx9pzhj 3722 50 21.4 21.4 CD cord-005646-xhx9pzhj 3722 51 % % NN cord-005646-xhx9pzhj 3722 52 of of IN cord-005646-xhx9pzhj 3722 53 cases case NNS cord-005646-xhx9pzhj 3722 54 . . . cord-005646-xhx9pzhj 3723 1 The the DT cord-005646-xhx9pzhj 3723 2 lesion lesion NN cord-005646-xhx9pzhj 3723 3 of of IN cord-005646-xhx9pzhj 3723 4 the the DT cord-005646-xhx9pzhj 3723 5 kidney kidney NN cord-005646-xhx9pzhj 3723 6 seemingly seemingly RB cord-005646-xhx9pzhj 3723 7 had have VBD cord-005646-xhx9pzhj 3723 8 little little JJ cord-005646-xhx9pzhj 3723 9 relation relation NN cord-005646-xhx9pzhj 3723 10 to to IN cord-005646-xhx9pzhj 3723 11 death death NN cord-005646-xhx9pzhj 3723 12 . . . cord-005646-xhx9pzhj 3724 1 Seven seven CD cord-005646-xhx9pzhj 3724 2 cases case NNS cord-005646-xhx9pzhj 3724 3 of of IN cord-005646-xhx9pzhj 3724 4 ictertts ictertt NNS cord-005646-xhx9pzhj 3724 5 due due IN cord-005646-xhx9pzhj 3724 6 to to IN cord-005646-xhx9pzhj 3724 7 an an DT cord-005646-xhx9pzhj 3724 8 increase increase NN cord-005646-xhx9pzhj 3724 9 of of IN cord-005646-xhx9pzhj 3724 10 direct direct JJ cord-005646-xhx9pzhj 3724 11 bilirubinemia bilirubinemia NN cord-005646-xhx9pzhj 3724 12 and and CC cord-005646-xhx9pzhj 3724 13 a a DT cord-005646-xhx9pzhj 3724 14 decrease decrease NN cord-005646-xhx9pzhj 3724 15 of of IN cord-005646-xhx9pzhj 3724 16 blood blood NN cord-005646-xhx9pzhj 3724 17 - - HYPH cord-005646-xhx9pzhj 3724 18 albumin albumin NN cord-005646-xhx9pzhj 3724 19 . . . cord-005646-xhx9pzhj 3725 1 -The -The : cord-005646-xhx9pzhj 3725 2 biological biological JJ cord-005646-xhx9pzhj 3725 3 characteristics characteristic NNS cord-005646-xhx9pzhj 3725 4 of of IN cord-005646-xhx9pzhj 3725 5 the the DT cord-005646-xhx9pzhj 3725 6 pathogen pathogen NN cord-005646-xhx9pzhj 3725 7 staphylococci staphylococcus NNS cord-005646-xhx9pzhj 3725 8 showed show VBD cord-005646-xhx9pzhj 3725 9 that that IN cord-005646-xhx9pzhj 3725 10 all all PDT cord-005646-xhx9pzhj 3725 11 the the DT cord-005646-xhx9pzhj 3725 12 75 75 CD cord-005646-xhx9pzhj 3725 13 isolated isolate VBN cord-005646-xhx9pzhj 3725 14 specimens specimen NNS cord-005646-xhx9pzhj 3725 15 had have VBD cord-005646-xhx9pzhj 3725 16 positive positive JJ cord-005646-xhx9pzhj 3725 17 coagulaza coagulaza NN cord-005646-xhx9pzhj 3725 18 ; ; : cord-005646-xhx9pzhj 3725 19 the the DT cord-005646-xhx9pzhj 3725 20 specimens specimen NNS cord-005646-xhx9pzhj 3725 21 from from IN cord-005646-xhx9pzhj 3725 22 the the DT cord-005646-xhx9pzhj 3725 23 dead dead JJ cord-005646-xhx9pzhj 3725 24 patients patient NNS cord-005646-xhx9pzhj 3725 25 were be VBD cord-005646-xhx9pzhj 3725 26 less less RBR cord-005646-xhx9pzhj 3725 27 semiti semiti NNP cord-005646-xhx9pzhj 3725 28 ~ ~ NFP cord-005646-xhx9pzhj 3725 29 e e XX cord-005646-xhx9pzhj 3725 30 to to IN cord-005646-xhx9pzhj 3725 31 , , , cord-005646-xhx9pzhj 3725 32 mad mad JJ cord-005646-xhx9pzhj 3726 1 ~t ~t . cord-005646-xhx9pzhj 3727 1 to to IN cord-005646-xhx9pzhj 3727 2 mali~ mali~ NNP cord-005646-xhx9pzhj 3727 3 Overag Overag NNP cord-005646-xhx9pzhj 3727 4 death death NN cord-005646-xhx9pzhj 3727 5 rate rate NN cord-005646-xhx9pzhj 3727 6 was be VBD cord-005646-xhx9pzhj 3727 7 34.7 34.7 CD cord-005646-xhx9pzhj 3727 8 % % NN cord-005646-xhx9pzhj 3727 9 ( ( -LRB- cord-005646-xhx9pzhj 3727 10 24/75 24/75 CD cord-005646-xhx9pzhj 3727 11 ) ) -RRB- cord-005646-xhx9pzhj 3727 12 . . . cord-005646-xhx9pzhj 3728 1 The the DT cord-005646-xhx9pzhj 3728 2 fungal fungal JJ cord-005646-xhx9pzhj 3728 3 infection infection NN cord-005646-xhx9pzhj 3728 4 to to IN cord-005646-xhx9pzhj 3728 5 fusariun fusariun NNP cord-005646-xhx9pzhj 3728 6 species specie NNS cord-005646-xhx9pzhj 3728 7 in in IN cord-005646-xhx9pzhj 3728 8 immunocompromissed immunocompromissed JJ cord-005646-xhx9pzhj 3728 9 child child NN cord-005646-xhx9pzhj 3728 10 have have VBP cord-005646-xhx9pzhj 3728 11 been be VBN cord-005646-xhx9pzhj 3728 12 reported report VBN cord-005646-xhx9pzhj 3728 13 in in IN cord-005646-xhx9pzhj 3728 14 the the DT cord-005646-xhx9pzhj 3728 15 literature literature NN cord-005646-xhx9pzhj 3728 16 with with IN cord-005646-xhx9pzhj 3728 17 a a DT cord-005646-xhx9pzhj 3728 18 rare rare JJ cord-005646-xhx9pzhj 3728 19 , , , cord-005646-xhx9pzhj 3728 20 severe severe JJ cord-005646-xhx9pzhj 3728 21 and and CC cord-005646-xhx9pzhj 3728 22 high high JJ cord-005646-xhx9pzhj 3728 23 , , , cord-005646-xhx9pzhj 3728 24 mortality mortality NN cord-005646-xhx9pzhj 3728 25 rate rate NN cord-005646-xhx9pzhj 3728 26 in in IN cord-005646-xhx9pzhj 3728 27 spite.of spite.of VBG cord-005646-xhx9pzhj 3728 28 the the DT cord-005646-xhx9pzhj 3728 29 use use NN cord-005646-xhx9pzhj 3728 30 of of IN cord-005646-xhx9pzhj 3728 31 antifungal antifungal JJ cord-005646-xhx9pzhj 3728 32 drugs drug NNS cord-005646-xhx9pzhj 3728 33 . . . cord-005646-xhx9pzhj 3729 1 We -PRON- PRP cord-005646-xhx9pzhj 3729 2 report report VBP cord-005646-xhx9pzhj 3729 3 a a DT cord-005646-xhx9pzhj 3729 4 case case NN cord-005646-xhx9pzhj 3729 5 of of IN cord-005646-xhx9pzhj 3729 6 successful successful JJ cord-005646-xhx9pzhj 3729 7 treatment treatment NN cord-005646-xhx9pzhj 3729 8 of of IN cord-005646-xhx9pzhj 3729 9 a a DT cord-005646-xhx9pzhj 3729 10 severe severe JJ cord-005646-xhx9pzhj 3729 11 disseminated disseminate VBN cord-005646-xhx9pzhj 3729 12 fusariun fusariun JJ cord-005646-xhx9pzhj 3729 13 infection infection NN cord-005646-xhx9pzhj 3729 14 in in IN cord-005646-xhx9pzhj 3729 15 a a DT cord-005646-xhx9pzhj 3729 16 ll ll JJ cord-005646-xhx9pzhj 3729 17 - - HYPH cord-005646-xhx9pzhj 3729 18 year year NN cord-005646-xhx9pzhj 3729 19 - - HYPH cord-005646-xhx9pzhj 3729 20 old old JJ cord-005646-xhx9pzhj 3729 21 boy boy NN cord-005646-xhx9pzhj 3729 22 with with IN cord-005646-xhx9pzhj 3729 23 acute acute JJ cord-005646-xhx9pzhj 3729 24 lymphocytic lymphocytic JJ cord-005646-xhx9pzhj 3729 25 leukemia leukemia NN cord-005646-xhx9pzhj 3729 26 ( ( -LRB- cord-005646-xhx9pzhj 3729 27 LLA LLA NNP cord-005646-xhx9pzhj 3729 28 - - HYPH cord-005646-xhx9pzhj 3729 29 L3 L3 NNP cord-005646-xhx9pzhj 3729 30 ) ) -RRB- cord-005646-xhx9pzhj 3729 31 , , , cord-005646-xhx9pzhj 3729 32 after after IN cord-005646-xhx9pzhj 3729 33 use use VB cord-005646-xhx9pzhj 3729 34 a a DT cord-005646-xhx9pzhj 3729 35 chemotherapy chemotherapy NN cord-005646-xhx9pzhj 3729 36 followed follow VBN cord-005646-xhx9pzhj 3729 37 by by IN cord-005646-xhx9pzhj 3729 38 absolute absolute JJ cord-005646-xhx9pzhj 3729 39 granuloeytopenia granuloeytopenia NNP cord-005646-xhx9pzhj 3729 40 . . . cord-005646-xhx9pzhj 3730 1 The the DT cord-005646-xhx9pzhj 3730 2 patient patient NN cord-005646-xhx9pzhj 3730 3 developed develop VBD cord-005646-xhx9pzhj 3730 4 fever fever NN cord-005646-xhx9pzhj 3730 5 , , , cord-005646-xhx9pzhj 3730 6 skin skin NN cord-005646-xhx9pzhj 3730 7 lesions lesion NNS cord-005646-xhx9pzhj 3730 8 , , , cord-005646-xhx9pzhj 3730 9 pneumonia pneumonia NN cord-005646-xhx9pzhj 3730 10 and and CC cord-005646-xhx9pzhj 3730 11 fungaemia fungaemia NN cord-005646-xhx9pzhj 3730 12 . . . cord-005646-xhx9pzhj 3731 1 Fusariun Fusariun NNP cord-005646-xhx9pzhj 3731 2 species specie NNS cord-005646-xhx9pzhj 3731 3 was be VBD cord-005646-xhx9pzhj 3731 4 cultured culture VBN cord-005646-xhx9pzhj 3731 5 from from IN cord-005646-xhx9pzhj 3731 6 the the DT cord-005646-xhx9pzhj 3731 7 blood blood NN cord-005646-xhx9pzhj 3731 8 , , , cord-005646-xhx9pzhj 3731 9 necrotic necrotic JJ cord-005646-xhx9pzhj 3731 10 skin skin NN cord-005646-xhx9pzhj 3731 11 lesions lesion NNS cord-005646-xhx9pzhj 3731 12 and and CC cord-005646-xhx9pzhj 3731 13 lung lung NN cord-005646-xhx9pzhj 3731 14 secretion secretion NN cord-005646-xhx9pzhj 3731 15 . . . cord-005646-xhx9pzhj 3732 1 The the DT cord-005646-xhx9pzhj 3732 2 child child NN cord-005646-xhx9pzhj 3732 3 developed develop VBD cord-005646-xhx9pzhj 3732 4 multiple multiple JJ cord-005646-xhx9pzhj 3732 5 organ organ NN cord-005646-xhx9pzhj 3732 6 system system NN cord-005646-xhx9pzhj 3732 7 disfunctiou disfunctiou VBN cord-005646-xhx9pzhj 3732 8 in in IN cord-005646-xhx9pzhj 3732 9 spite spite NN cord-005646-xhx9pzhj 3732 10 of of IN cord-005646-xhx9pzhj 3732 11 use use NN cord-005646-xhx9pzhj 3732 12 broad broad JJ cord-005646-xhx9pzhj 3732 13 spectrum spectrum NN cord-005646-xhx9pzhj 3732 14 antibiotcs antibiotc NNS cord-005646-xhx9pzhj 3732 15 and and CC cord-005646-xhx9pzhj 3732 16 antimycotic antimycotic JJ cord-005646-xhx9pzhj 3732 17 therapy therapy NN cord-005646-xhx9pzhj 3732 18 needing need VBG cord-005646-xhx9pzhj 3732 19 . . . cord-005646-xhx9pzhj 3733 1 UCI UCI NNP cord-005646-xhx9pzhj 3733 2 during during IN cord-005646-xhx9pzhj 3733 3 18 18 CD cord-005646-xhx9pzhj 3733 4 days day NNS cord-005646-xhx9pzhj 3733 5 . . . cord-005646-xhx9pzhj 3734 1 The the DT cord-005646-xhx9pzhj 3734 2 patient patient NN cord-005646-xhx9pzhj 3734 3 receive receive VBP cord-005646-xhx9pzhj 3734 4 suport suport NN cord-005646-xhx9pzhj 3734 5 treatment treatment NN cord-005646-xhx9pzhj 3734 6 ( ( -LRB- cord-005646-xhx9pzhj 3734 7 mechanical mechanical JJ cord-005646-xhx9pzhj 3734 8 ventilation ventilation NN cord-005646-xhx9pzhj 3734 9 , , , cord-005646-xhx9pzhj 3734 10 Inotropie Inotropie NNP cord-005646-xhx9pzhj 3734 11 d~.ugs d~.ugs NNP cord-005646-xhx9pzhj 3734 12 , , , cord-005646-xhx9pzhj 3734 13 Diuretics Diuretics NNPS cord-005646-xhx9pzhj 3734 14 , , , cord-005646-xhx9pzhj 3734 15 Imunestimulants Imunestimulants NNP cord-005646-xhx9pzhj 3734 16 , , , cord-005646-xhx9pzhj 3734 17 Blood Blood NNP cord-005646-xhx9pzhj 3734 18 Components Components NNP cord-005646-xhx9pzhj 3734 19 , , , cord-005646-xhx9pzhj 3734 20 a a DT cord-005646-xhx9pzhj 3734 21 broad broad JJ cord-005646-xhx9pzhj 3734 22 spectrum spectrum NN cord-005646-xhx9pzhj 3734 23 antibiotes antibiote NNS cord-005646-xhx9pzhj 3734 24 and and CC cord-005646-xhx9pzhj 3734 25 antifungal antifungal JJ cord-005646-xhx9pzhj 3734 26 agents agent NNS cord-005646-xhx9pzhj 3734 27 ) ) -RRB- cord-005646-xhx9pzhj 3734 28 . . . cord-005646-xhx9pzhj 3735 1 We -PRON- PRP cord-005646-xhx9pzhj 3735 2 absorved absorve VBD cord-005646-xhx9pzhj 3735 3 a a DT cord-005646-xhx9pzhj 3735 4 gradual gradual JJ cord-005646-xhx9pzhj 3735 5 recovery recovery NN cord-005646-xhx9pzhj 3735 6 in in IN cord-005646-xhx9pzhj 3735 7 the the DT cord-005646-xhx9pzhj 3735 8 white white JJ cord-005646-xhx9pzhj 3735 9 blood blood NN cord-005646-xhx9pzhj 3735 10 cell cell NN cord-005646-xhx9pzhj 3735 11 count count NN cord-005646-xhx9pzhj 3735 12 and and CC cord-005646-xhx9pzhj 3735 13 regression regression NN cord-005646-xhx9pzhj 3735 14 on on IN cord-005646-xhx9pzhj 3735 15 the the DT cord-005646-xhx9pzhj 3735 16 sites site NNS cord-005646-xhx9pzhj 3735 17 of of IN cord-005646-xhx9pzhj 3735 18 infection infection NN cord-005646-xhx9pzhj 3735 19 . . . cord-005646-xhx9pzhj 3736 1 The the DT cord-005646-xhx9pzhj 3736 2 association association NN cord-005646-xhx9pzhj 3736 3 of of IN cord-005646-xhx9pzhj 3736 4 preeoce preeoce NNP cord-005646-xhx9pzhj 3736 5 diagnostic diagnostic NNP cord-005646-xhx9pzhj 3736 6 and and CC cord-005646-xhx9pzhj 3736 7 the the DT cord-005646-xhx9pzhj 3736 8 terapentic terapentic JJ cord-005646-xhx9pzhj 3736 9 with with IN cord-005646-xhx9pzhj 3736 10 increase increase NN cord-005646-xhx9pzhj 3736 11 in in IN cord-005646-xhx9pzhj 3736 12 the the DT cord-005646-xhx9pzhj 3736 13 white white JJ cord-005646-xhx9pzhj 3736 14 blood blood NN cord-005646-xhx9pzhj 3736 15 cell cell NN cord-005646-xhx9pzhj 3736 16 count count NN cord-005646-xhx9pzhj 3736 17 was be VBD cord-005646-xhx9pzhj 3736 18 the the DT cord-005646-xhx9pzhj 3736 19 most most RBS cord-005646-xhx9pzhj 3736 20 important important JJ cord-005646-xhx9pzhj 3736 21 in in IN cord-005646-xhx9pzhj 3736 22 a a DT cord-005646-xhx9pzhj 3736 23 successful successful JJ cord-005646-xhx9pzhj 3736 24 treatment treatment NN cord-005646-xhx9pzhj 3736 25 . . . cord-005646-xhx9pzhj 3737 1 A a DT cord-005646-xhx9pzhj 3737 2 5 5 CD cord-005646-xhx9pzhj 3737 3 year year NN cord-005646-xhx9pzhj 3737 4 old old JJ cord-005646-xhx9pzhj 3737 5 African african JJ cord-005646-xhx9pzhj 3737 6 - - HYPH cord-005646-xhx9pzhj 3737 7 American american JJ cord-005646-xhx9pzhj 3737 8 child child NN cord-005646-xhx9pzhj 3737 9 suffered suffer VBD cord-005646-xhx9pzhj 3737 10 a a DT cord-005646-xhx9pzhj 3737 11 severe severe JJ cord-005646-xhx9pzhj 3737 12 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3737 13 injury injury NN cord-005646-xhx9pzhj 3737 14 in in IN cord-005646-xhx9pzhj 3737 15 a a DT cord-005646-xhx9pzhj 3737 16 house house NN cord-005646-xhx9pzhj 3737 17 fire fire NN cord-005646-xhx9pzhj 3737 18 . . . cord-005646-xhx9pzhj 3738 1 Initial initial JJ cord-005646-xhx9pzhj 3738 2 survey survey NN cord-005646-xhx9pzhj 3738 3 revealed reveal VBD cord-005646-xhx9pzhj 3738 4 1 1 CD cord-005646-xhx9pzhj 3738 5 % % NN cord-005646-xhx9pzhj 3738 6 total total JJ cord-005646-xhx9pzhj 3738 7 body body NN cord-005646-xhx9pzhj 3738 8 surface surface NN cord-005646-xhx9pzhj 3738 9 burns burn NNS cord-005646-xhx9pzhj 3738 10 , , , cord-005646-xhx9pzhj 3738 11 soot soot NN cord-005646-xhx9pzhj 3738 12 on on IN cord-005646-xhx9pzhj 3738 13 the the DT cord-005646-xhx9pzhj 3738 14 face face NN cord-005646-xhx9pzhj 3738 15 , , , cord-005646-xhx9pzhj 3738 16 and and CC cord-005646-xhx9pzhj 3738 17 bloody bloody JJ cord-005646-xhx9pzhj 3738 18 endotracheal endotracheal NN cord-005646-xhx9pzhj 3738 19 secretions secretion NNS cord-005646-xhx9pzhj 3738 20 . . . cord-005646-xhx9pzhj 3739 1 Initial initial JJ cord-005646-xhx9pzhj 3739 2 chest chest NN cord-005646-xhx9pzhj 3739 3 radiograph radiograph NN cord-005646-xhx9pzhj 3739 4 revealed reveal VBD cord-005646-xhx9pzhj 3739 5 diffuse diffuse JJ cord-005646-xhx9pzhj 3739 6 , , , cord-005646-xhx9pzhj 3739 7 bilateral bilateral JJ cord-005646-xhx9pzhj 3739 8 infiltrates infiltrate NNS cord-005646-xhx9pzhj 3739 9 . . . cord-005646-xhx9pzhj 3740 1 Severe severe JJ cord-005646-xhx9pzhj 3740 2 respiratory respiratory JJ cord-005646-xhx9pzhj 3740 3 failure failure NN cord-005646-xhx9pzhj 3740 4 with with IN cord-005646-xhx9pzhj 3740 5 an an DT cord-005646-xhx9pzhj 3740 6 oxygenation oxygenation NN cord-005646-xhx9pzhj 3740 7 ratio ratio NN cord-005646-xhx9pzhj 3740 8 of of IN cord-005646-xhx9pzhj 3740 9 73 73 CD cord-005646-xhx9pzhj 3740 10 rapidly rapidly RB cord-005646-xhx9pzhj 3740 11 developed develop VBN cord-005646-xhx9pzhj 3740 12 . . . cord-005646-xhx9pzhj 3741 1 He -PRON- PRP cord-005646-xhx9pzhj 3741 2 developed develop VBD cord-005646-xhx9pzhj 3741 3 a a DT cord-005646-xhx9pzhj 3741 4 pneumomediastinum pneumomediastinum NN cord-005646-xhx9pzhj 3741 5 and and CC cord-005646-xhx9pzhj 3741 6 subcutaneous subcutaneous JJ cord-005646-xhx9pzhj 3741 7 emphysema emphysema NN cord-005646-xhx9pzhj 3741 8 . . . cord-005646-xhx9pzhj 3742 1 Although although IN cord-005646-xhx9pzhj 3742 2 transient transient JJ cord-005646-xhx9pzhj 3742 3 improvement improvement NN cord-005646-xhx9pzhj 3742 4 occurred occur VBD cord-005646-xhx9pzhj 3742 5 with with IN cord-005646-xhx9pzhj 3742 6 inverse inverse NN cord-005646-xhx9pzhj 3742 7 I -PRON- PRP cord-005646-xhx9pzhj 3742 8 : : : cord-005646-xhx9pzhj 3742 9 E e NN cord-005646-xhx9pzhj 3742 10 ventilation ventilation NN cord-005646-xhx9pzhj 3742 11 and and CC cord-005646-xhx9pzhj 3742 12 surfactant surfactant NN cord-005646-xhx9pzhj 3742 13 , , , cord-005646-xhx9pzhj 3742 14 he -PRON- PRP cord-005646-xhx9pzhj 3742 15 became become VBD cord-005646-xhx9pzhj 3742 16 more more RBR cord-005646-xhx9pzhj 3742 17 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3742 18 ( ( -LRB- cord-005646-xhx9pzhj 3742 19 SAC2 SAC2 NNP cord-005646-xhx9pzhj 3742 20 as as RB cord-005646-xhx9pzhj 3742 21 low low JJ cord-005646-xhx9pzhj 3742 22 as as IN cord-005646-xhx9pzhj 3742 23 47 47 CD cord-005646-xhx9pzhj 3742 24 % % NN cord-005646-xhx9pzhj 3742 25 ) ) -RRB- cord-005646-xhx9pzhj 3742 26 and and CC cord-005646-xhx9pzhj 3742 27 acidotic acidotic JJ cord-005646-xhx9pzhj 3742 28 . . . cord-005646-xhx9pzhj 3743 1 On on IN cord-005646-xhx9pzhj 3743 2 day day NN cord-005646-xhx9pzhj 3743 3 2 2 CD cord-005646-xhx9pzhj 3743 4 post post NN cord-005646-xhx9pzhj 3743 5 injury injury NN cord-005646-xhx9pzhj 3743 6 , , , cord-005646-xhx9pzhj 3743 7 he -PRON- PRP cord-005646-xhx9pzhj 3743 8 was be VBD cord-005646-xhx9pzhj 3743 9 placed place VBN cord-005646-xhx9pzhj 3743 10 on on IN cord-005646-xhx9pzhj 3743 11 venc venc NN cord-005646-xhx9pzhj 3743 12 ~ ~ NFP cord-005646-xhx9pzhj 3743 13 venous venous JJ cord-005646-xhx9pzhj 3743 14 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 3743 15 life life NN cord-005646-xhx9pzhj 3743 16 support support NN cord-005646-xhx9pzhj 3743 17 ( ( -LRB- cord-005646-xhx9pzhj 3743 18 ECLS ECLS NNP cord-005646-xhx9pzhj 3743 19 ) ) -RRB- cord-005646-xhx9pzhj 3743 20 . . . cord-005646-xhx9pzhj 3744 1 On on IN cord-005646-xhx9pzhj 3744 2 ECLS ECLS NNP cord-005646-xhx9pzhj 3744 3 day day NN cord-005646-xhx9pzhj 3744 4 30 30 CD cord-005646-xhx9pzhj 3744 5 he -PRON- PRP cord-005646-xhx9pzhj 3744 6 was be VBD cord-005646-xhx9pzhj 3744 7 decannulated decannulate VBN cord-005646-xhx9pzhj 3744 8 . . . cord-005646-xhx9pzhj 3745 1 Chest chest NN cord-005646-xhx9pzhj 3745 2 radiograph radiograph NN cord-005646-xhx9pzhj 3745 3 on on IN cord-005646-xhx9pzhj 3745 4 ECLS ECLS NNP cord-005646-xhx9pzhj 3745 5 day day NN cord-005646-xhx9pzhj 3745 6 15 15 CD cord-005646-xhx9pzhj 3745 7 showed show VBD cord-005646-xhx9pzhj 3745 8 an an DT cord-005646-xhx9pzhj 3745 9 opacity opacity NN cord-005646-xhx9pzhj 3745 10 in in IN cord-005646-xhx9pzhj 3745 11 the the DT cord-005646-xhx9pzhj 3745 12 left left JJ cord-005646-xhx9pzhj 3745 13 chest chest NN cord-005646-xhx9pzhj 3745 14 . . . cord-005646-xhx9pzhj 3746 1 Ultrasound ultrasound NN cord-005646-xhx9pzhj 3746 2 of of IN cord-005646-xhx9pzhj 3746 3 the the DT cord-005646-xhx9pzhj 3746 4 left left JJ cord-005646-xhx9pzhj 3746 5 chest chest NN cord-005646-xhx9pzhj 3746 6 was be VBD cord-005646-xhx9pzhj 3746 7 consistent consistent JJ cord-005646-xhx9pzhj 3746 8 with with IN cord-005646-xhx9pzhj 3746 9 atelectasis atelectasis NN cord-005646-xhx9pzhj 3746 10 rather rather RB cord-005646-xhx9pzhj 3746 11 than than IN cord-005646-xhx9pzhj 3746 12 pleural pleural JJ cord-005646-xhx9pzhj 3746 13 fluid fluid NN cord-005646-xhx9pzhj 3746 14 . . . cord-005646-xhx9pzhj 3747 1 Flexible flexible JJ cord-005646-xhx9pzhj 3747 2 bronchoseopy bronchoseopy NNS cord-005646-xhx9pzhj 3747 3 failed fail VBD cord-005646-xhx9pzhj 3747 4 to to TO cord-005646-xhx9pzhj 3747 5 reveal reveal VB cord-005646-xhx9pzhj 3747 6 any any DT cord-005646-xhx9pzhj 3747 7 obstruction obstruction NN cord-005646-xhx9pzhj 3747 8 in in IN cord-005646-xhx9pzhj 3747 9 the the DT cord-005646-xhx9pzhj 3747 10 left left JJ cord-005646-xhx9pzhj 3747 11 lung lung NN cord-005646-xhx9pzhj 3747 12 . . . cord-005646-xhx9pzhj 3748 1 A a DT cord-005646-xhx9pzhj 3748 2 computed compute VBN cord-005646-xhx9pzhj 3748 3 tomography tomography NN cord-005646-xhx9pzhj 3748 4 ( ( -LRB- cord-005646-xhx9pzhj 3748 5 CT CT NNP cord-005646-xhx9pzhj 3748 6 ) ) -RRB- cord-005646-xhx9pzhj 3748 7 seen see VBN cord-005646-xhx9pzhj 3748 8 of of IN cord-005646-xhx9pzhj 3748 9 the the DT cord-005646-xhx9pzhj 3748 10 chest chest NN cord-005646-xhx9pzhj 3748 11 , , , cord-005646-xhx9pzhj 3748 12 which which WDT cord-005646-xhx9pzhj 3748 13 was be VBD cord-005646-xhx9pzhj 3748 14 performed perform VBN cord-005646-xhx9pzhj 3748 15 after after IN cord-005646-xhx9pzhj 3748 16 decannulation decannulation NN cord-005646-xhx9pzhj 3748 17 , , , cord-005646-xhx9pzhj 3748 18 revealed reveal VBD cord-005646-xhx9pzhj 3748 19 a a DT cord-005646-xhx9pzhj 3748 20 large large JJ cord-005646-xhx9pzhj 3748 21 loculated loculate VBN cord-005646-xhx9pzhj 3748 22 collection collection NN cord-005646-xhx9pzhj 3748 23 of of IN cord-005646-xhx9pzhj 3748 24 fluid fluid NN cord-005646-xhx9pzhj 3748 25 in in IN cord-005646-xhx9pzhj 3748 26 the the DT cord-005646-xhx9pzhj 3748 27 left left JJ cord-005646-xhx9pzhj 3748 28 , , , cord-005646-xhx9pzhj 3748 29 anterior anterior JJ cord-005646-xhx9pzhj 3748 30 chest chest NN cord-005646-xhx9pzhj 3748 31 . . . cord-005646-xhx9pzhj 3749 1 Under under IN cord-005646-xhx9pzhj 3749 2 CT CT NNP cord-005646-xhx9pzhj 3749 3 guidance guidance NN cord-005646-xhx9pzhj 3749 4 , , , cord-005646-xhx9pzhj 3749 5 a a DT cord-005646-xhx9pzhj 3749 6 14 14 CD cord-005646-xhx9pzhj 3749 7 F F NNP cord-005646-xhx9pzhj 3749 8 cope cope VBP cord-005646-xhx9pzhj 3749 9 loop loop NN cord-005646-xhx9pzhj 3749 10 catheter catheter NN cord-005646-xhx9pzhj 3749 11 was be VBD cord-005646-xhx9pzhj 3749 12 inserted insert VBN cord-005646-xhx9pzhj 3749 13 and and CC cord-005646-xhx9pzhj 3749 14 40 40 CD cord-005646-xhx9pzhj 3749 15 cc cc NNS cord-005646-xhx9pzhj 3749 16 of of IN cord-005646-xhx9pzhj 3749 17 thick thick JJ cord-005646-xhx9pzhj 3749 18 blood blood NN cord-005646-xhx9pzhj 3749 19 was be VBD cord-005646-xhx9pzhj 3749 20 removed remove VBN cord-005646-xhx9pzhj 3749 21 , , , cord-005646-xhx9pzhj 3749 22 Follow Follow NNP cord-005646-xhx9pzhj 3749 23 - - HYPH cord-005646-xhx9pzhj 3749 24 up up RP cord-005646-xhx9pzhj 3749 25 CT CT NNP cord-005646-xhx9pzhj 3749 26 performed perform VBN cord-005646-xhx9pzhj 3749 27 immediately immediately RB cord-005646-xhx9pzhj 3749 28 after after IN cord-005646-xhx9pzhj 3749 29 this this DT cord-005646-xhx9pzhj 3749 30 procedure procedure NN cord-005646-xhx9pzhj 3749 31 revealed reveal VBD cord-005646-xhx9pzhj 3749 32 minimal minimal JJ cord-005646-xhx9pzhj 3749 33 change change NN cord-005646-xhx9pzhj 3749 34 in in IN cord-005646-xhx9pzhj 3749 35 the the DT cord-005646-xhx9pzhj 3749 36 size size NN cord-005646-xhx9pzhj 3749 37 of of IN cord-005646-xhx9pzhj 3749 38 the the DT cord-005646-xhx9pzhj 3749 39 fluid fluid JJ cord-005646-xhx9pzhj 3749 40 cavity cavity NN cord-005646-xhx9pzhj 3749 41 . . . cord-005646-xhx9pzhj 3750 1 Over over IN cord-005646-xhx9pzhj 3750 2 the the DT cord-005646-xhx9pzhj 3750 3 next next JJ cord-005646-xhx9pzhj 3750 4 48 48 CD cord-005646-xhx9pzhj 3750 5 hr hr NN cord-005646-xhx9pzhj 3750 6 , , , cord-005646-xhx9pzhj 3750 7 we -PRON- PRP cord-005646-xhx9pzhj 3750 8 instilled instill VBD cord-005646-xhx9pzhj 3750 9 urokinase urokinase NN cord-005646-xhx9pzhj 3750 10 20,000 20,000 CD cord-005646-xhx9pzhj 3750 11 units unit NNS cord-005646-xhx9pzhj 3750 12 over over IN cord-005646-xhx9pzhj 3750 13 20 20 CD cord-005646-xhx9pzhj 3750 14 minutes minute NNS cord-005646-xhx9pzhj 3750 15 every every DT cord-005646-xhx9pzhj 3750 16 two two CD cord-005646-xhx9pzhj 3750 17 hours hour NNS cord-005646-xhx9pzhj 3750 18 . . . cord-005646-xhx9pzhj 3751 1 A a DT cord-005646-xhx9pzhj 3751 2 30 30 CD cord-005646-xhx9pzhj 3751 3 minute minute NN cord-005646-xhx9pzhj 3751 4 dwell dwell NN cord-005646-xhx9pzhj 3751 5 time time NN cord-005646-xhx9pzhj 3751 6 was be VBD cord-005646-xhx9pzhj 3751 7 allowed allow VBN cord-005646-xhx9pzhj 3751 8 before before IN cord-005646-xhx9pzhj 3751 9 draining drain VBG cord-005646-xhx9pzhj 3751 10 the the DT cord-005646-xhx9pzhj 3751 11 fluid fluid NN cord-005646-xhx9pzhj 3751 12 . . . cord-005646-xhx9pzhj 3752 1 Repeat repeat NN cord-005646-xhx9pzhj 3752 2 CT CT NNP cord-005646-xhx9pzhj 3752 3 scan scan NN cord-005646-xhx9pzhj 3752 4 done do VBN cord-005646-xhx9pzhj 3752 5 at at IN cord-005646-xhx9pzhj 3752 6 the the DT cord-005646-xhx9pzhj 3752 7 end end NN cord-005646-xhx9pzhj 3752 8 of of IN cord-005646-xhx9pzhj 3752 9 the the DT cord-005646-xhx9pzhj 3752 10 urokinase urokinase NN cord-005646-xhx9pzhj 3752 11 infusion infusion NN cord-005646-xhx9pzhj 3752 12 showed show VBD cord-005646-xhx9pzhj 3752 13 a a DT cord-005646-xhx9pzhj 3752 14 marked marked JJ cord-005646-xhx9pzhj 3752 15 decrease decrease NN cord-005646-xhx9pzhj 3752 16 in in IN cord-005646-xhx9pzhj 3752 17 the the DT cord-005646-xhx9pzhj 3752 18 size size NN cord-005646-xhx9pzhj 3752 19 of of IN cord-005646-xhx9pzhj 3752 20 the the DT cord-005646-xhx9pzhj 3752 21 fluid fluid JJ cord-005646-xhx9pzhj 3752 22 cavity cavity NN cord-005646-xhx9pzhj 3752 23 . . . cord-005646-xhx9pzhj 3753 1 ACT ACT NNP cord-005646-xhx9pzhj 3753 2 scan scan NNP cord-005646-xhx9pzhj 3753 3 was be VBD cord-005646-xhx9pzhj 3753 4 not not RB cord-005646-xhx9pzhj 3753 5 performed perform VBN cord-005646-xhx9pzhj 3753 6 prior prior RB cord-005646-xhx9pzhj 3753 7 to to IN cord-005646-xhx9pzhj 3753 8 decarmulation decarmulation NN cord-005646-xhx9pzhj 3753 9 because because IN cord-005646-xhx9pzhj 3753 10 the the DT cord-005646-xhx9pzhj 3753 11 ECLS ECLS NNP cord-005646-xhx9pzhj 3753 12 circuit circuit NN cord-005646-xhx9pzhj 3753 13 tubing tubing NN cord-005646-xhx9pzhj 3753 14 was be VBD cord-005646-xhx9pzhj 3753 15 too too RB cord-005646-xhx9pzhj 3753 16 short short JJ cord-005646-xhx9pzhj 3753 17 to to TO cord-005646-xhx9pzhj 3753 18 allow allow VB cord-005646-xhx9pzhj 3753 19 appropriate appropriate JJ cord-005646-xhx9pzhj 3753 20 positioning positioning NN cord-005646-xhx9pzhj 3753 21 of of IN cord-005646-xhx9pzhj 3753 22 the the DT cord-005646-xhx9pzhj 3753 23 child child NN cord-005646-xhx9pzhj 3753 24 in in IN cord-005646-xhx9pzhj 3753 25 the the DT cord-005646-xhx9pzhj 3753 26 CT CT NNP cord-005646-xhx9pzhj 3753 27 scanner scanner NN cord-005646-xhx9pzhj 3753 28 . . . cord-005646-xhx9pzhj 3754 1 After after IN cord-005646-xhx9pzhj 3754 2 a a DT cord-005646-xhx9pzhj 3754 3 CT CT NNP cord-005646-xhx9pzhj 3754 4 scan scan NN cord-005646-xhx9pzhj 3754 5 revealed reveal VBN cord-005646-xhx9pzhj 3754 6 loculated loculate VBN cord-005646-xhx9pzhj 3754 7 pleural pleural JJ cord-005646-xhx9pzhj 3754 8 fluid fluid NN cord-005646-xhx9pzhj 3754 9 , , , cord-005646-xhx9pzhj 3754 10 a a DT cord-005646-xhx9pzhj 3754 11 simple simple JJ cord-005646-xhx9pzhj 3754 12 drainage drainage NN cord-005646-xhx9pzhj 3754 13 procedure procedure NN cord-005646-xhx9pzhj 3754 14 was be VBD cord-005646-xhx9pzhj 3754 15 diagnostic diagnostic JJ cord-005646-xhx9pzhj 3754 16 but but CC cord-005646-xhx9pzhj 3754 17 inadequate inadequate JJ cord-005646-xhx9pzhj 3754 18 treatment treatment NN cord-005646-xhx9pzhj 3754 19 . . . cord-005646-xhx9pzhj 3755 1 We -PRON- PRP cord-005646-xhx9pzhj 3755 2 were be VBD cord-005646-xhx9pzhj 3755 3 able able JJ cord-005646-xhx9pzhj 3755 4 to to TO cord-005646-xhx9pzhj 3755 5 successfully successfully RB cord-005646-xhx9pzhj 3755 6 dissolve dissolve VB cord-005646-xhx9pzhj 3755 7 the the DT cord-005646-xhx9pzhj 3755 8 thrombus thrombus NN cord-005646-xhx9pzhj 3755 9 after after IN cord-005646-xhx9pzhj 3755 10 48 48 CD cord-005646-xhx9pzhj 3755 11 hr hr NN cord-005646-xhx9pzhj 3755 12 of of IN cord-005646-xhx9pzhj 3755 13 urokinase urokinase NN cord-005646-xhx9pzhj 3755 14 therapy therapy NN cord-005646-xhx9pzhj 3755 15 even even RB cord-005646-xhx9pzhj 3755 16 though though IN cord-005646-xhx9pzhj 3755 17 the the DT cord-005646-xhx9pzhj 3755 18 thrombus thrombus NN cord-005646-xhx9pzhj 3755 19 was be VBD cord-005646-xhx9pzhj 3755 20 > > NFP cord-005646-xhx9pzhj 3755 21 14 14 CD cord-005646-xhx9pzhj 3755 22 days day NNS cord-005646-xhx9pzhj 3755 23 old old JJ cord-005646-xhx9pzhj 3755 24 . . . cord-005646-xhx9pzhj 3756 1 We -PRON- PRP cord-005646-xhx9pzhj 3756 2 suggest suggest VBP cord-005646-xhx9pzhj 3756 3 that that IN cord-005646-xhx9pzhj 3756 4 large large JJ cord-005646-xhx9pzhj 3756 5 loculated loculate VBN cord-005646-xhx9pzhj 3756 6 plenral plenral JJ cord-005646-xhx9pzhj 3756 7 thrombi thrombi NNP cord-005646-xhx9pzhj 3756 8 which which WDT cord-005646-xhx9pzhj 3756 9 develop develop VBP cord-005646-xhx9pzhj 3756 10 as as IN cord-005646-xhx9pzhj 3756 11 a a DT cord-005646-xhx9pzhj 3756 12 complication complication NN cord-005646-xhx9pzhj 3756 13 of of IN cord-005646-xhx9pzhj 3756 14 ECLS ECLS NNP cord-005646-xhx9pzhj 3756 15 therapy therapy NN cord-005646-xhx9pzhj 3756 16 may may MD cord-005646-xhx9pzhj 3756 17 be be VB cord-005646-xhx9pzhj 3756 18 successfully successfully RB cord-005646-xhx9pzhj 3756 19 managed manage VBN cord-005646-xhx9pzhj 3756 20 with with IN cord-005646-xhx9pzhj 3756 21 urokinase urokinase NN cord-005646-xhx9pzhj 3756 22 infusion infusion NN cord-005646-xhx9pzhj 3756 23 . . . cord-005646-xhx9pzhj 3757 1 Introduction introduction NN cord-005646-xhx9pzhj 3757 2 : : : cord-005646-xhx9pzhj 3757 3 Haemorrhages Haemorrhages NNP cord-005646-xhx9pzhj 3757 4 , , , cord-005646-xhx9pzhj 3757 5 particularly particularly RB cord-005646-xhx9pzhj 3757 6 intracranial intracranial JJ cord-005646-xhx9pzhj 3757 7 , , , cord-005646-xhx9pzhj 3757 8 are be VBP cord-005646-xhx9pzhj 3757 9 major major JJ cord-005646-xhx9pzhj 3757 10 complications complication NNS cord-005646-xhx9pzhj 3757 11 experienced experience VBN cord-005646-xhx9pzhj 3757 12 in in IN cord-005646-xhx9pzhj 3757 13 10 10 CD cord-005646-xhx9pzhj 3757 14 - - SYM cord-005646-xhx9pzhj 3757 15 35 35 CD cord-005646-xhx9pzhj 3757 16 % % NN cord-005646-xhx9pzhj 3757 17 of of IN cord-005646-xhx9pzhj 3757 18 neonates neonate NNS cord-005646-xhx9pzhj 3757 19 treated treat VBN cord-005646-xhx9pzhj 3757 20 with with IN cord-005646-xhx9pzhj 3757 21 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 3757 22 circulation circulation NN cord-005646-xhx9pzhj 3757 23 . . . cord-005646-xhx9pzhj 3758 1 An an DT cord-005646-xhx9pzhj 3758 2 induced induce VBN cord-005646-xhx9pzhj 3758 3 thrombocytopenia thrombocytopenia NN cord-005646-xhx9pzhj 3758 4 and and CC cord-005646-xhx9pzhj 3758 5 impaired impaired JJ cord-005646-xhx9pzhj 3758 6 platelet platelet NN cord-005646-xhx9pzhj 3758 7 function function NN cord-005646-xhx9pzhj 3758 8 play play VB cord-005646-xhx9pzhj 3758 9 a a DT cord-005646-xhx9pzhj 3758 10 key key JJ cord-005646-xhx9pzhj 3758 11 role role NN cord-005646-xhx9pzhj 3758 12 in in IN cord-005646-xhx9pzhj 3758 13 the the DT cord-005646-xhx9pzhj 3758 14 increased increase VBN cord-005646-xhx9pzhj 3758 15 bleeding bleeding NN cord-005646-xhx9pzhj 3758 16 tendency tendency NN cord-005646-xhx9pzhj 3758 17 observed observe VBD cord-005646-xhx9pzhj 3758 18 in in IN cord-005646-xhx9pzhj 3758 19 these these DT cord-005646-xhx9pzhj 3758 20 patients patient NNS cord-005646-xhx9pzhj 3758 21 . . . cord-005646-xhx9pzhj 3759 1 The the DT cord-005646-xhx9pzhj 3759 2 aim aim NN cord-005646-xhx9pzhj 3759 3 of of IN cord-005646-xhx9pzhj 3759 4 the the DT cord-005646-xhx9pzhj 3759 5 present present JJ cord-005646-xhx9pzhj 3759 6 study study NN cord-005646-xhx9pzhj 3759 7 was be VBD cord-005646-xhx9pzhj 3759 8 to to TO cord-005646-xhx9pzhj 3759 9 establish establish VB cord-005646-xhx9pzhj 3759 10 a a DT cord-005646-xhx9pzhj 3759 11 dose dose NN cord-005646-xhx9pzhj 3759 12 - - HYPH cord-005646-xhx9pzhj 3759 13 respons respons NN cord-005646-xhx9pzhj 3759 14 curve curve NN cord-005646-xhx9pzhj 3759 15 for for IN cord-005646-xhx9pzhj 3759 16 the the DT cord-005646-xhx9pzhj 3759 17 effect effect NN cord-005646-xhx9pzhj 3759 18 of of IN cord-005646-xhx9pzhj 3759 19 a a DT cord-005646-xhx9pzhj 3759 20 synthetic synthetic JJ cord-005646-xhx9pzhj 3759 21 protease protease NN cord-005646-xhx9pzhj 3759 22 inhibiting inhibit VBG cord-005646-xhx9pzhj 3759 23 agent agent NN cord-005646-xhx9pzhj 3759 24 , , , cord-005646-xhx9pzhj 3759 25 Nafamostat Nafamostat NNP cord-005646-xhx9pzhj 3759 26 Mesilate Mesilate NNP cord-005646-xhx9pzhj 3759 27 ( ( -LRB- cord-005646-xhx9pzhj 3759 28 FUT-175 FUT-175 NNP cord-005646-xhx9pzhj 3759 29 ) ) -RRB- cord-005646-xhx9pzhj 3759 30 , , , cord-005646-xhx9pzhj 3759 31 on on IN cord-005646-xhx9pzhj 3759 32 platelet platelet NN cord-005646-xhx9pzhj 3759 33 membrane membrane NN cord-005646-xhx9pzhj 3759 34 glycoprotein glycoprotein NN cord-005646-xhx9pzhj 3759 35 density density NN cord-005646-xhx9pzhj 3759 36 and and CC cord-005646-xhx9pzhj 3759 37 platelet platelet NN cord-005646-xhx9pzhj 3759 38 activation activation NN cord-005646-xhx9pzhj 3759 39 during during IN cord-005646-xhx9pzhj 3759 40 experimental experimental JJ cord-005646-xhx9pzhj 3759 41 perfusion perfusion NN cord-005646-xhx9pzhj 3759 42 . . . cord-005646-xhx9pzhj 3760 1 Methods method NNS cord-005646-xhx9pzhj 3760 2 : : : cord-005646-xhx9pzhj 3761 1 Two two CD cord-005646-xhx9pzhj 3761 2 identical identical JJ cord-005646-xhx9pzhj 3761 3 Extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 3761 4 Life life NN cord-005646-xhx9pzhj 3761 5 Support support NN cord-005646-xhx9pzhj 3761 6 ( ( -LRB- cord-005646-xhx9pzhj 3761 7 ECLS ECLS NNP cord-005646-xhx9pzhj 3761 8 ) ) -RRB- cord-005646-xhx9pzhj 3761 9 circuits circuit NNS cord-005646-xhx9pzhj 3761 10 were be VBD cord-005646-xhx9pzhj 3761 11 primed prime VBN cord-005646-xhx9pzhj 3761 12 with with IN cord-005646-xhx9pzhj 3761 13 fresh fresh JJ cord-005646-xhx9pzhj 3761 14 , , , cord-005646-xhx9pzhj 3761 15 heparinized heparinized JJ cord-005646-xhx9pzhj 3761 16 human human JJ cord-005646-xhx9pzhj 3761 17 blood blood NN cord-005646-xhx9pzhj 3761 18 and and CC cord-005646-xhx9pzhj 3761 19 circulated circulate VBD cord-005646-xhx9pzhj 3761 20 for for IN cord-005646-xhx9pzhj 3761 21 24 24 CD cord-005646-xhx9pzhj 3761 22 h. h. NNP cord-005646-xhx9pzhj 3761 23 Four four CD cord-005646-xhx9pzhj 3761 24 different different JJ cord-005646-xhx9pzhj 3761 25 concentrations concentration NNS cord-005646-xhx9pzhj 3761 26 of of IN cord-005646-xhx9pzhj 3761 27 FUT-175 FUT-175 NNP cord-005646-xhx9pzhj 3761 28 ( ( -LRB- cord-005646-xhx9pzhj 3761 29 7.12 7.12 CD cord-005646-xhx9pzhj 3761 30 mg mg NNP cord-005646-xhx9pzhj 3761 31 / / SYM cord-005646-xhx9pzhj 3761 32 L L NNP cord-005646-xhx9pzhj 3761 33 blood blood NN cord-005646-xhx9pzhj 3761 34 / / SYM cord-005646-xhx9pzhj 3761 35 h h NN cord-005646-xhx9pzhj 3761 36 ; ; : cord-005646-xhx9pzhj 3761 37 14.25 14.25 CD cord-005646-xhx9pzhj 3761 38 mg mg NNP cord-005646-xhx9pzhj 3761 39 / / SYM cord-005646-xhx9pzhj 3761 40 L L NNP cord-005646-xhx9pzhj 3761 41 / / SYM cord-005646-xhx9pzhj 3761 42 h h NN cord-005646-xhx9pzhj 3761 43 ; ; : cord-005646-xhx9pzhj 3761 44 14.25 14.25 CD cord-005646-xhx9pzhj 3761 45 mg mg NNP cord-005646-xhx9pzhj 3761 46 / / SYM cord-005646-xhx9pzhj 3761 47 L L NNP cord-005646-xhx9pzhj 3761 48 / / SYM cord-005646-xhx9pzhj 3761 49 h+25 h+25 ADD cord-005646-xhx9pzhj 3761 50 % % NN cord-005646-xhx9pzhj 3761 51 bolus bolus NN cord-005646-xhx9pzhj 3761 52 at at IN cord-005646-xhx9pzhj 3761 53 the the DT cord-005646-xhx9pzhj 3761 54 start start NN cord-005646-xhx9pzhj 3761 55 of of IN cord-005646-xhx9pzhj 3761 56 the the DT cord-005646-xhx9pzhj 3761 57 perfusion perfusion NN cord-005646-xhx9pzhj 3761 58 and and CC cord-005646-xhx9pzhj 3761 59 2&5mg 2&5mg CD cord-005646-xhx9pzhj 3761 60 / / SYM cord-005646-xhx9pzhj 3761 61 L L NNP cord-005646-xhx9pzhj 3761 62 / / SYM cord-005646-xhx9pzhj 3761 63 h+25 h+25 ADD cord-005646-xhx9pzhj 3761 64 % % NN cord-005646-xhx9pzhj 3761 65 bolus bolus NN cord-005646-xhx9pzhj 3761 66 ) ) -RRB- cord-005646-xhx9pzhj 3761 67 were be VBD cord-005646-xhx9pzhj 3761 68 used use VBN cord-005646-xhx9pzhj 3761 69 in in IN cord-005646-xhx9pzhj 3761 70 different different JJ cord-005646-xhx9pzhj 3761 71 perfusion perfusion NN cord-005646-xhx9pzhj 3761 72 experiments experiment NNS cord-005646-xhx9pzhj 3761 73 . . . cord-005646-xhx9pzhj 3762 1 A a DT cord-005646-xhx9pzhj 3762 2 total total NN cord-005646-xhx9pzhj 3762 3 of of IN cord-005646-xhx9pzhj 3762 4 eight eight CD cord-005646-xhx9pzhj 3762 5 paired pair VBN cord-005646-xhx9pzhj 3762 6 experiments experiment NNS cord-005646-xhx9pzhj 3762 7 were be VBD cord-005646-xhx9pzhj 3762 8 performed perform VBN cord-005646-xhx9pzhj 3762 9 . . . cord-005646-xhx9pzhj 3763 1 Platelet platelet NN cord-005646-xhx9pzhj 3763 2 count count NN cord-005646-xhx9pzhj 3763 3 , , , cord-005646-xhx9pzhj 3763 4 plasma plasma NN cord-005646-xhx9pzhj 3763 5 betathromboglobulin betathromboglobulin NN cord-005646-xhx9pzhj 3763 6 levels level NNS cord-005646-xhx9pzhj 3763 7 and and CC cord-005646-xhx9pzhj 3763 8 platelet platelet NN cord-005646-xhx9pzhj 3763 9 membrane membrane NN cord-005646-xhx9pzhj 3763 10 density density NN cord-005646-xhx9pzhj 3763 11 of of IN cord-005646-xhx9pzhj 3763 12 glycoprotein glycoprotein NN cord-005646-xhx9pzhj 3763 13 Ib Ib NNP cord-005646-xhx9pzhj 3763 14 and and CC cord-005646-xhx9pzhj 3763 15 lib/ lib/ ADD cord-005646-xhx9pzhj 3764 1 Ilia Ilia NNP cord-005646-xhx9pzhj 3764 2 were be VBD cord-005646-xhx9pzhj 3764 3 followed follow VBN cord-005646-xhx9pzhj 3764 4 as as RB cord-005646-xhx9pzhj 3764 5 well well RB cord-005646-xhx9pzhj 3764 6 as as IN cord-005646-xhx9pzhj 3764 7 plasma plasma NN cord-005646-xhx9pzhj 3764 8 concentration concentration NN cord-005646-xhx9pzhj 3764 9 of of IN cord-005646-xhx9pzhj 3764 10 haemoglobin haemoglobin NN cord-005646-xhx9pzhj 3764 11 . . . cord-005646-xhx9pzhj 3765 1 Results result NNS cord-005646-xhx9pzhj 3765 2 : : : cord-005646-xhx9pzhj 3766 1 A a DT cord-005646-xhx9pzhj 3766 2 protective protective JJ cord-005646-xhx9pzhj 3766 3 effect effect NN cord-005646-xhx9pzhj 3766 4 of of IN cord-005646-xhx9pzhj 3766 5 the the DT cord-005646-xhx9pzhj 3766 6 agent agent NN cord-005646-xhx9pzhj 3766 7 on on IN cord-005646-xhx9pzhj 3766 8 platelet platelet NN cord-005646-xhx9pzhj 3766 9 count count NN cord-005646-xhx9pzhj 3766 10 , , , cord-005646-xhx9pzhj 3766 11 plasma plasma NN cord-005646-xhx9pzhj 3766 12 concentration concentration NN cord-005646-xhx9pzhj 3766 13 of of IN cord-005646-xhx9pzhj 3766 14 BTG BTG NNP cord-005646-xhx9pzhj 3766 15 and and CC cord-005646-xhx9pzhj 3766 16 platelet platelet NN cord-005646-xhx9pzhj 3766 17 membrane membrane NN cord-005646-xhx9pzhj 3766 18 GPIb GPIb NNS cord-005646-xhx9pzhj 3766 19 could could MD cord-005646-xhx9pzhj 3766 20 be be VB cord-005646-xhx9pzhj 3766 21 observed observe VBN cord-005646-xhx9pzhj 3766 22 during during IN cord-005646-xhx9pzhj 3766 23 the the DT cord-005646-xhx9pzhj 3766 24 first first JJ cord-005646-xhx9pzhj 3766 25 3 3 CD cord-005646-xhx9pzhj 3766 26 hours hour NNS cord-005646-xhx9pzhj 3766 27 of of IN cord-005646-xhx9pzhj 3766 28 the the DT cord-005646-xhx9pzhj 3766 29 perfusion perfusion NN cord-005646-xhx9pzhj 3766 30 when when WRB cord-005646-xhx9pzhj 3766 31 a a DT cord-005646-xhx9pzhj 3766 32 bolus bolus NN cord-005646-xhx9pzhj 3766 33 dose dose NN cord-005646-xhx9pzhj 3766 34 was be VBD cord-005646-xhx9pzhj 3766 35 added add VBN cord-005646-xhx9pzhj 3766 36 . . . cord-005646-xhx9pzhj 3767 1 No no DT cord-005646-xhx9pzhj 3767 2 positive positive JJ cord-005646-xhx9pzhj 3767 3 effect effect NN cord-005646-xhx9pzhj 3767 4 could could MD cord-005646-xhx9pzhj 3767 5 be be VB cord-005646-xhx9pzhj 3767 6 recorded record VBN cord-005646-xhx9pzhj 3767 7 with with IN cord-005646-xhx9pzhj 3767 8 the the DT cord-005646-xhx9pzhj 3767 9 two two CD cord-005646-xhx9pzhj 3767 10 lower low JJR cord-005646-xhx9pzhj 3767 11 doses dose NNS cord-005646-xhx9pzhj 3767 12 used use VBN cord-005646-xhx9pzhj 3767 13 . . . cord-005646-xhx9pzhj 3768 1 Plasma plasma NN cord-005646-xhx9pzhj 3768 2 concentration concentration NN cord-005646-xhx9pzhj 3768 3 of of IN cord-005646-xhx9pzhj 3768 4 haemoglobin haemoglobin NN cord-005646-xhx9pzhj 3768 5 was be VBD cord-005646-xhx9pzhj 3768 6 higher high JJR cord-005646-xhx9pzhj 3768 7 in in IN cord-005646-xhx9pzhj 3768 8 all all PDT cord-005646-xhx9pzhj 3768 9 the the DT cord-005646-xhx9pzhj 3768 10 FUT fut NN cord-005646-xhx9pzhj 3768 11 - - HYPH cord-005646-xhx9pzhj 3768 12 circuits circuit NNS cord-005646-xhx9pzhj 3768 13 compared compare VBN cord-005646-xhx9pzhj 3768 14 to to IN cord-005646-xhx9pzhj 3768 15 the the DT cord-005646-xhx9pzhj 3768 16 control control NN cord-005646-xhx9pzhj 3768 17 circuits circuit NNS cord-005646-xhx9pzhj 3768 18 . . . cord-005646-xhx9pzhj 3769 1 Conclusion conclusion NN cord-005646-xhx9pzhj 3769 2 : : : cord-005646-xhx9pzhj 3770 1 The the DT cord-005646-xhx9pzhj 3770 2 addition addition NN cord-005646-xhx9pzhj 3770 3 of of IN cord-005646-xhx9pzhj 3770 4 a a DT cord-005646-xhx9pzhj 3770 5 bolus bolus NN cord-005646-xhx9pzhj 3770 6 dose dose NN cord-005646-xhx9pzhj 3770 7 of of IN cord-005646-xhx9pzhj 3770 8 FUT-175 fut-175 XX cord-005646-xhx9pzhj 3770 9 at at IN cord-005646-xhx9pzhj 3770 10 the the DT cord-005646-xhx9pzhj 3770 11 start start NN cord-005646-xhx9pzhj 3770 12 of of IN cord-005646-xhx9pzhj 3770 13 the the DT cord-005646-xhx9pzhj 3770 14 perfusion perfusion NN cord-005646-xhx9pzhj 3770 15 seem seem VBP cord-005646-xhx9pzhj 3770 16 to to TO cord-005646-xhx9pzhj 3770 17 induce induce VB cord-005646-xhx9pzhj 3770 18 a a DT cord-005646-xhx9pzhj 3770 19 protective protective JJ cord-005646-xhx9pzhj 3770 20 effect effect NN cord-005646-xhx9pzhj 3770 21 on on IN cord-005646-xhx9pzhj 3770 22 platelets platelet NNS cord-005646-xhx9pzhj 3770 23 during during IN cord-005646-xhx9pzhj 3770 24 the the DT cord-005646-xhx9pzhj 3770 25 first first JJ cord-005646-xhx9pzhj 3770 26 hours hour NNS cord-005646-xhx9pzhj 3770 27 of of IN cord-005646-xhx9pzhj 3770 28 perfusion perfusion NN cord-005646-xhx9pzhj 3770 29 . . . cord-005646-xhx9pzhj 3771 1 Extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 3771 2 membrane membrane NN cord-005646-xhx9pzhj 3771 3 oxygenation oxygenation NN cord-005646-xhx9pzhj 3771 4 ( ( -LRB- cord-005646-xhx9pzhj 3771 5 EMCO EMCO NNP cord-005646-xhx9pzhj 3771 6 ) ) -RRB- cord-005646-xhx9pzhj 3771 7 is be VBZ cord-005646-xhx9pzhj 3771 8 a a DT cord-005646-xhx9pzhj 3771 9 form form NN cord-005646-xhx9pzhj 3771 10 of of IN cord-005646-xhx9pzhj 3771 11 invasive invasive JJ cord-005646-xhx9pzhj 3771 12 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 3771 13 support support NN cord-005646-xhx9pzhj 3771 14 that that WDT cord-005646-xhx9pzhj 3771 15 can can MD cord-005646-xhx9pzhj 3771 16 provide provide VB cord-005646-xhx9pzhj 3771 17 imporary imporary JJ cord-005646-xhx9pzhj 3771 18 physiologic physiologic JJ cord-005646-xhx9pzhj 3771 19 stabilisation stabilisation NN cord-005646-xhx9pzhj 3771 20 in in IN cord-005646-xhx9pzhj 3771 21 reversible reversible JJ cord-005646-xhx9pzhj 3771 22 circulatory circulatory JJ cord-005646-xhx9pzhj 3771 23 failure failure NN cord-005646-xhx9pzhj 3771 24 and and CC cord-005646-xhx9pzhj 3771 25 or or CC cord-005646-xhx9pzhj 3771 26 respiratory respiratory JJ cord-005646-xhx9pzhj 3771 27 failure failure NN cord-005646-xhx9pzhj 3771 28 . . . cord-005646-xhx9pzhj 3772 1 We -PRON- PRP cord-005646-xhx9pzhj 3772 2 reviewed review VBD cord-005646-xhx9pzhj 3772 3 our -PRON- PRP$ cord-005646-xhx9pzhj 3772 4 expierence expierence NN cord-005646-xhx9pzhj 3772 5 with with IN cord-005646-xhx9pzhj 3772 6 extra extra JJ cord-005646-xhx9pzhj 3772 7 corporeal corporeal JJ cord-005646-xhx9pzhj 3772 8 membrane membrane NN cord-005646-xhx9pzhj 3772 9 oxygenetion oxygenetion NN cord-005646-xhx9pzhj 3772 10 in in IN cord-005646-xhx9pzhj 3772 11 4 4 CD cord-005646-xhx9pzhj 3772 12 children child NNS cord-005646-xhx9pzhj 3772 13 aged age VBN cord-005646-xhx9pzhj 3772 14 1 1 CD cord-005646-xhx9pzhj 3772 15 day day NN cord-005646-xhx9pzhj 3772 16 to to IN cord-005646-xhx9pzhj 3772 17 4 4 CD cord-005646-xhx9pzhj 3772 18 year year NN cord-005646-xhx9pzhj 3772 19 between between IN cord-005646-xhx9pzhj 3772 20 1991 1991 CD cord-005646-xhx9pzhj 3772 21 and and CC cord-005646-xhx9pzhj 3772 22 1995 1995 CD cord-005646-xhx9pzhj 3772 23 . . . cord-005646-xhx9pzhj 3773 1 Two two CD cord-005646-xhx9pzhj 3773 2 neonates neonate NNS cord-005646-xhx9pzhj 3773 3 was be VBD cord-005646-xhx9pzhj 3773 4 succesfully succesfully RB cord-005646-xhx9pzhj 3773 5 decanulated decanulate VBN cord-005646-xhx9pzhj 3773 6 , , , cord-005646-xhx9pzhj 3773 7 but but CC cord-005646-xhx9pzhj 3773 8 died die VBD cord-005646-xhx9pzhj 3773 9 1 1 CD cord-005646-xhx9pzhj 3773 10 - - SYM cord-005646-xhx9pzhj 3773 11 2 2 CD cord-005646-xhx9pzhj 3773 12 well well RB cord-005646-xhx9pzhj 3773 13 after after IN cord-005646-xhx9pzhj 3773 14 decanulation decanulation NN cord-005646-xhx9pzhj 3773 15 due due IN cord-005646-xhx9pzhj 3773 16 to to IN cord-005646-xhx9pzhj 3773 17 septic septic JJ cord-005646-xhx9pzhj 3773 18 complictions compliction NNS cord-005646-xhx9pzhj 3773 19 . . . cord-005646-xhx9pzhj 3774 1 One one CD cord-005646-xhx9pzhj 3774 2 child child NN cord-005646-xhx9pzhj 3774 3 4 4 CD cord-005646-xhx9pzhj 3774 4 years year NNS cord-005646-xhx9pzhj 3774 5 old old JJ cord-005646-xhx9pzhj 3774 6 , , , cord-005646-xhx9pzhj 3774 7 one one CD cord-005646-xhx9pzhj 3774 8 neonates neonate NNS cord-005646-xhx9pzhj 3774 9 died die VBD cord-005646-xhx9pzhj 3774 10 on on IN cord-005646-xhx9pzhj 3774 11 day day NN cord-005646-xhx9pzhj 3774 12 5 5 CD cord-005646-xhx9pzhj 3774 13 and and CC cord-005646-xhx9pzhj 3774 14 day day NN cord-005646-xhx9pzhj 3774 15 " " '' cord-005646-xhx9pzhj 3774 16 7 7 CD cord-005646-xhx9pzhj 3774 17 respectively respectively RB cord-005646-xhx9pzhj 3774 18 while while IN cord-005646-xhx9pzhj 3774 19 still still RB cord-005646-xhx9pzhj 3774 20 on on IN cord-005646-xhx9pzhj 3774 21 EMCO EMCO NNP cord-005646-xhx9pzhj 3774 22 . . . cord-005646-xhx9pzhj 3775 1 Complication complication NN cord-005646-xhx9pzhj 3775 2 which which WDT cord-005646-xhx9pzhj 3775 3 were be VBD cord-005646-xhx9pzhj 3775 4 and and CC cord-005646-xhx9pzhj 3775 5 encountered encounter VBN cord-005646-xhx9pzhj 3775 6 were be VBD cord-005646-xhx9pzhj 3775 7 heavy heavy JJ cord-005646-xhx9pzhj 3775 8 bleeding bleeding NN cord-005646-xhx9pzhj 3775 9 in in IN cord-005646-xhx9pzhj 3775 10 case case NN cord-005646-xhx9pzhj 3775 11 1 1 CD cord-005646-xhx9pzhj 3775 12 ( ( -LRB- cord-005646-xhx9pzhj 3775 13 child child NN cord-005646-xhx9pzhj 3775 14 ) ) -RRB- cord-005646-xhx9pzhj 3775 15 , , , cord-005646-xhx9pzhj 3775 16 4 4 CD cord-005646-xhx9pzhj 3775 17 ( ( -LRB- cord-005646-xhx9pzhj 3775 18 neonate neonate NN cord-005646-xhx9pzhj 3775 19 ) ) -RRB- cord-005646-xhx9pzhj 3775 20 and and CC cord-005646-xhx9pzhj 3775 21 raceway raceway NN cord-005646-xhx9pzhj 3775 22 rupture rupture NN cord-005646-xhx9pzhj 3775 23 in in IN cord-005646-xhx9pzhj 3775 24 case case NN cord-005646-xhx9pzhj 3775 25 2 2 CD cord-005646-xhx9pzhj 3775 26 ( ( -LRB- cord-005646-xhx9pzhj 3775 27 neonate neonate NN cord-005646-xhx9pzhj 3775 28 ) ) -RRB- cord-005646-xhx9pzhj 3775 29 . . . cord-005646-xhx9pzhj 3776 1 Problems problem NNS cord-005646-xhx9pzhj 3776 2 which which WDT cord-005646-xhx9pzhj 3776 3 are be VBP cord-005646-xhx9pzhj 3776 4 specific specific JJ cord-005646-xhx9pzhj 3776 5 developing develop VBG cord-005646-xhx9pzhj 3776 6 countries country NNS cord-005646-xhx9pzhj 3776 7 like like IN cord-005646-xhx9pzhj 3776 8 Indonisia Indonisia NNS cord-005646-xhx9pzhj 3776 9 are be VBP cord-005646-xhx9pzhj 3776 10 : : : cord-005646-xhx9pzhj 3776 11 high high JJ cord-005646-xhx9pzhj 3776 12 cost cost NN cord-005646-xhx9pzhj 3776 13 ( ( -LRB- cord-005646-xhx9pzhj 3776 14 20.000 20.000 CD cord-005646-xhx9pzhj 3776 15 US US NNP cord-005646-xhx9pzhj 3776 16 for for IN cord-005646-xhx9pzhj 3776 17 7 7 CD cord-005646-xhx9pzhj 3776 18 days day NNS cord-005646-xhx9pzhj 3776 19 ) ) -RRB- cord-005646-xhx9pzhj 3776 20 difficulty difficulty NN cord-005646-xhx9pzhj 3776 21 in in IN cord-005646-xhx9pzhj 3776 22 transportation transportation NN cord-005646-xhx9pzhj 3776 23 ( ( -LRB- cord-005646-xhx9pzhj 3776 24 transporting transport VBG cord-005646-xhx9pzhj 3776 25 intubated intubate VBN cord-005646-xhx9pzhj 3776 26 baby baby NN cord-005646-xhx9pzhj 3776 27 ) ) -RRB- cord-005646-xhx9pzhj 3776 28 from from IN cord-005646-xhx9pzhj 3776 29 the the DT cord-005646-xhx9pzhj 3776 30 orgin orgin NNP cord-005646-xhx9pzhj 3776 31 hospital hospital NN cord-005646-xhx9pzhj 3776 32 , , , cord-005646-xhx9pzhj 3776 33 lack lack NN cord-005646-xhx9pzhj 3776 34 of of IN cord-005646-xhx9pzhj 3776 35 knowledge knowledge NN cord-005646-xhx9pzhj 3776 36 and and CC cord-005646-xhx9pzhj 3776 37 understanding understanding NN cord-005646-xhx9pzhj 3776 38 of of IN cord-005646-xhx9pzhj 3776 39 the the DT cord-005646-xhx9pzhj 3776 40 primary primary JJ cord-005646-xhx9pzhj 3776 41 physician physician NN cord-005646-xhx9pzhj 3776 42 and and CC cord-005646-xhx9pzhj 3776 43 nm nm NN cord-005646-xhx9pzhj 3776 44 - - HYPH cord-005646-xhx9pzhj 3776 45 ses se NNS cord-005646-xhx9pzhj 3776 46 and and CC cord-005646-xhx9pzhj 3776 47 difficulty difficulty NN cord-005646-xhx9pzhj 3776 48 organizing organize VBG cord-005646-xhx9pzhj 3776 49 in in IN cord-005646-xhx9pzhj 3776 50 24 24 CD cord-005646-xhx9pzhj 3776 51 hours hour NNS cord-005646-xhx9pzhj 3776 52 EMCO EMCO NNP cord-005646-xhx9pzhj 3776 53 team team NN cord-005646-xhx9pzhj 3776 54 . . . cord-005646-xhx9pzhj 3777 1 RESNRATORY RESNRATORY NNP cord-005646-xhx9pzhj 3777 2 MON1TOR MON1TOR NNP cord-005646-xhx9pzhj 3777 3 / / SYM cord-005646-xhx9pzhj 3777 4 NG NG NNP cord-005646-xhx9pzhj 3777 5 IN in IN cord-005646-xhx9pzhj 3777 6 PICU PICU NNP cord-005646-xhx9pzhj 3777 7 Z Z NNP cord-005646-xhx9pzhj 3777 8 , , , cord-005646-xhx9pzhj 3777 9 ZJVKOVIC ZJVKOVIC NNP cord-005646-xhx9pzhj 3777 10 , , , cord-005646-xhx9pzhj 3777 11 S. S. NNP cord-005646-xhx9pzhj 3777 12 MIHAILOVIC MIHAILOVIC NNP cord-005646-xhx9pzhj 3777 13 , , , cord-005646-xhx9pzhj 3777 14 O o UH cord-005646-xhx9pzhj 3777 15 , , , cord-005646-xhx9pzhj 3778 1 TOSEV TOSEV NNP cord-005646-xhx9pzhj 3778 2 Respiratory respiratory JJ cord-005646-xhx9pzhj 3778 3 monitoring monitoring NN cord-005646-xhx9pzhj 3778 4 in in IN cord-005646-xhx9pzhj 3778 5 Pediatric Pediatric NNP cord-005646-xhx9pzhj 3778 6 Intensive Intensive NNP cord-005646-xhx9pzhj 3778 7 Care Care NNP cord-005646-xhx9pzhj 3778 8 Unit Unit NNP cord-005646-xhx9pzhj 3778 9 0PICU 0PICU . cord-005646-xhx9pzhj 3778 10 ) ) -RRB- cord-005646-xhx9pzhj 3778 11 provide provide VB cord-005646-xhx9pzhj 3778 12 the the DT cord-005646-xhx9pzhj 3778 13 importartt importartt NNP cord-005646-xhx9pzhj 3778 14 informations information NNS cord-005646-xhx9pzhj 3778 15 for for IN cord-005646-xhx9pzhj 3778 16 understanding understanding NN cord-005646-xhx9pzhj 3778 17 of of IN cord-005646-xhx9pzhj 3778 18 the the DT cord-005646-xhx9pzhj 3778 19 pathophysiology pathophysiology NN cord-005646-xhx9pzhj 3778 20 of of IN cord-005646-xhx9pzhj 3778 21 the the DT cord-005646-xhx9pzhj 3778 22 clinical clinical JJ cord-005646-xhx9pzhj 3778 23 signs sign NNS cord-005646-xhx9pzhj 3778 24 , , , cord-005646-xhx9pzhj 3778 25 aid aid VB cord-005646-xhx9pzhj 3778 26 with with IN cord-005646-xhx9pzhj 3778 27 the the DT cord-005646-xhx9pzhj 3778 28 diagnosis diagnosis NN cord-005646-xhx9pzhj 3778 29 , , , cord-005646-xhx9pzhj 3778 30 and and CC cord-005646-xhx9pzhj 3778 31 assist assist VB cord-005646-xhx9pzhj 3778 32 in in IN cord-005646-xhx9pzhj 3778 33 therapeutic therapeutic JJ cord-005646-xhx9pzhj 3778 34 management management NN cord-005646-xhx9pzhj 3778 35 and and CC cord-005646-xhx9pzhj 3778 36 predicting predict VBG cord-005646-xhx9pzhj 3778 37 prognosis prognosis NN cord-005646-xhx9pzhj 3778 38 . . . cord-005646-xhx9pzhj 3779 1 Pien Pien NNP cord-005646-xhx9pzhj 3779 2 in in IN cord-005646-xhx9pzhj 3779 3 Children Children NNP cord-005646-xhx9pzhj 3779 4 's 's POS cord-005646-xhx9pzhj 3779 5 Hospital Hospital NNP cord-005646-xhx9pzhj 3779 6 for for IN cord-005646-xhx9pzhj 3779 7 ~flmonary ~flmonary NNP cord-005646-xhx9pzhj 3779 8 Diseases Diseases NNPS cord-005646-xhx9pzhj 3779 9 and and CC cord-005646-xhx9pzhj 3779 10 Tuberentosis Tuberentosis NNP cord-005646-xhx9pzhj 3779 11 remained remain VBD cord-005646-xhx9pzhj 3779 12 for for IN cord-005646-xhx9pzhj 3779 13 the the DT cord-005646-xhx9pzhj 3779 14 t t NN cord-005646-xhx9pzhj 3780 1 ~s't ~s't NFP cord-005646-xhx9pzhj 3780 2 two two CD cord-005646-xhx9pzhj 3780 3 end end NN cord-005646-xhx9pzhj 3781 1 a a DT cord-005646-xhx9pzhj 3781 2 half half NN cord-005646-xhx9pzhj 3781 3 years year NNS cord-005646-xhx9pzhj 3781 4 relatively relatively RB cord-005646-xhx9pzhj 3781 5 limited limited JJ cord-005646-xhx9pzhj 3781 6 for for IN cord-005646-xhx9pzhj 3781 7 diagnoMic diagnomic JJ cord-005646-xhx9pzhj 3781 8 tools tool NNS cord-005646-xhx9pzhj 3781 9 and and CC cord-005646-xhx9pzhj 3781 10 therapeutic therapeutic JJ cord-005646-xhx9pzhj 3781 11 regimens regimen NNS cord-005646-xhx9pzhj 3781 12 , , , cord-005646-xhx9pzhj 3781 13 mostly mostly RB cord-005646-xhx9pzhj 3781 14 because because IN cord-005646-xhx9pzhj 3781 15 of of IN cord-005646-xhx9pzhj 3781 16 the the DT cord-005646-xhx9pzhj 3781 17 poor poor JJ cord-005646-xhx9pzhj 3781 18 fmnaeial fmnaeial NNP cord-005646-xhx9pzhj 3781 19 suptx suptx NNP cord-005646-xhx9pzhj 3781 20 ~ ~ NFP cord-005646-xhx9pzhj 3781 21 rt rt NNP cord-005646-xhx9pzhj 3781 22 . . . cord-005646-xhx9pzhj 3782 1 The the DT cord-005646-xhx9pzhj 3782 2 number number NN cord-005646-xhx9pzhj 3782 3 of of IN cord-005646-xhx9pzhj 3782 4 children child NNS cord-005646-xhx9pzhj 3782 5 admitted admit VBN cord-005646-xhx9pzhj 3782 6 for for IN cord-005646-xhx9pzhj 3782 7 aurae aurae NNP cord-005646-xhx9pzhj 3782 8 asthmatic asthmatic JJ cord-005646-xhx9pzhj 3782 9 at.lzek~ at.lzek~ NNP cord-005646-xhx9pzhj 3782 10 severe severe JJ cord-005646-xhx9pzhj 3782 11 pneumonias pneumonia NNS cord-005646-xhx9pzhj 3782 12 , , , cord-005646-xhx9pzhj 3782 13 bronehiolitis bronehiolitis NNP cord-005646-xhx9pzhj 3782 14 , , , cord-005646-xhx9pzhj 3782 15 complicated complicated JJ cord-005646-xhx9pzhj 3782 16 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3782 17 tuberculosis tuberculosis NN cord-005646-xhx9pzhj 3782 18 , , , cord-005646-xhx9pzhj 3782 19 foreign foreign JJ cord-005646-xhx9pzhj 3782 20 bodies body NNS cord-005646-xhx9pzhj 3782 21 and and CC cord-005646-xhx9pzhj 3782 22 exacerbations exacerbation NNS cord-005646-xhx9pzhj 3782 23 of of IN cord-005646-xhx9pzhj 3782 24 ehronit ehronit NNP cord-005646-xhx9pzhj 3782 25 ' ' '' cord-005646-xhx9pzhj 3782 26 . . . cord-005646-xhx9pzhj 3783 1 pulatonary pulatonary NNP cord-005646-xhx9pzhj 3783 2 diseases diseases NNPS cord-005646-xhx9pzhj 3783 3 was be VBD cord-005646-xhx9pzhj 3783 4 t362 t362 JJ cord-005646-xhx9pzhj 3783 5 . . . cord-005646-xhx9pzhj 3784 1 For for IN cord-005646-xhx9pzhj 3784 2 all all DT cord-005646-xhx9pzhj 3784 3 patients patient NNS cord-005646-xhx9pzhj 3784 4 the the DT cord-005646-xhx9pzhj 3784 5 respirator respirator NN cord-005646-xhx9pzhj 3784 6 ' ' POS cord-005646-xhx9pzhj 3784 7 monitoring monitoring NN cord-005646-xhx9pzhj 3784 8 system system NN cord-005646-xhx9pzhj 3784 9 means mean VBZ cord-005646-xhx9pzhj 3784 10 : : : cord-005646-xhx9pzhj 3784 11 physie physie NNP cord-005646-xhx9pzhj 3784 12 ~ ~ NFP cord-005646-xhx9pzhj 3784 13 d d NNP cord-005646-xhx9pzhj 3784 14 examination examination NN cord-005646-xhx9pzhj 3784 15 , , , cord-005646-xhx9pzhj 3784 16 ehe~ ehe~ NNP cord-005646-xhx9pzhj 3784 17 X X NNP cord-005646-xhx9pzhj 3784 18 rays ray NNS cord-005646-xhx9pzhj 3784 19 , , , cord-005646-xhx9pzhj 3784 20 capillary capillary JJ cord-005646-xhx9pzhj 3784 21 bltxxl bltxxl NNP cord-005646-xhx9pzhj 3784 22 gas gas NNP cord-005646-xhx9pzhj 3784 23 mmlyses mmlyses NNPS cord-005646-xhx9pzhj 3784 24 ( ( -LRB- cord-005646-xhx9pzhj 3784 25 vevv vevv NNP cord-005646-xhx9pzhj 3784 26 few few JJ cord-005646-xhx9pzhj 3784 27 ehiktren ehiktren NNP cord-005646-xhx9pzhj 3784 28 experienced experience VBD cord-005646-xhx9pzhj 3784 29 itwasive itwasive JJ cord-005646-xhx9pzhj 3784 30 arterial arterial JJ cord-005646-xhx9pzhj 3784 31 blt~.~'i blt~.~'i NNP cord-005646-xhx9pzhj 3784 32 gases gas NNS cord-005646-xhx9pzhj 3784 33 ) ) -RRB- cord-005646-xhx9pzhj 3784 34 , , , cord-005646-xhx9pzhj 3784 35 noninvasive noninvasive JJ cord-005646-xhx9pzhj 3784 36 oxyntctry oxyntctry NN cord-005646-xhx9pzhj 3784 37 , , , cord-005646-xhx9pzhj 3784 38 measuring measure VBG cord-005646-xhx9pzhj 3784 39 of of IN cord-005646-xhx9pzhj 3784 40 the the DT cord-005646-xhx9pzhj 3784 41 vital vital JJ cord-005646-xhx9pzhj 3784 42 capacity capacity NN cord-005646-xhx9pzhj 3784 43 in in IN cord-005646-xhx9pzhj 3784 44 coopo coopo NN cord-005646-xhx9pzhj 3784 45 - - HYPH cord-005646-xhx9pzhj 3784 46 able able JJ cord-005646-xhx9pzhj 3784 47 patients patient NNS cord-005646-xhx9pzhj 3784 48 , , , cord-005646-xhx9pzhj 3784 49 as as IN cord-005646-xhx9pzhj 3784 50 ~ ~ CD cord-005646-xhx9pzhj 3784 51 d d XX cord-005646-xhx9pzhj 3784 52 capnography capnography NN cord-005646-xhx9pzhj 3784 53 . . . cord-005646-xhx9pzhj 3785 1 Later later RB cord-005646-xhx9pzhj 3785 2 on on RB cord-005646-xhx9pzhj 3785 3 , , , cord-005646-xhx9pzhj 3785 4 after after IN cord-005646-xhx9pzhj 3785 5 the the DT cord-005646-xhx9pzhj 3785 6 imtial imtial JJ cord-005646-xhx9pzhj 3785 7 critical critical JJ cord-005646-xhx9pzhj 3785 8 illness illness NN cord-005646-xhx9pzhj 3785 9 , , , cord-005646-xhx9pzhj 3785 10 a a DT cord-005646-xhx9pzhj 3785 11 complete complete JJ cord-005646-xhx9pzhj 3785 12 hmg hmg NNP cord-005646-xhx9pzhj 3785 13 fimction fimction NN cord-005646-xhx9pzhj 3785 14 tests test NNS cord-005646-xhx9pzhj 3785 15 was be VBD cord-005646-xhx9pzhj 3785 16 performed perform VBN cord-005646-xhx9pzhj 3785 17 , , , cord-005646-xhx9pzhj 3785 18 as as RB cord-005646-xhx9pzhj 3785 19 well well RB cord-005646-xhx9pzhj 3785 20 , , . cord-005646-xhx9pzhj 3786 1 ~s ~s NNP cord-005646-xhx9pzhj 3786 2 bronehoscopy bronehoscopy NNP cord-005646-xhx9pzhj 3786 3 in in IN cord-005646-xhx9pzhj 3786 4 selected select VBN cord-005646-xhx9pzhj 3786 5 eases ease VBZ cord-005646-xhx9pzhj 3787 1 , , , cord-005646-xhx9pzhj 3787 2 ( ( -LRB- cord-005646-xhx9pzhj 3787 3 ~lr ~lr NNP cord-005646-xhx9pzhj 3787 4 experience experience NN cord-005646-xhx9pzhj 3787 5 revealed reveal VBD cord-005646-xhx9pzhj 3787 6 that that IN cord-005646-xhx9pzhj 3787 7 abotrt abotrt NN cord-005646-xhx9pzhj 3787 8 60 60 CD cord-005646-xhx9pzhj 3787 9 % % NN cord-005646-xhx9pzhj 3787 10 of of IN cord-005646-xhx9pzhj 3787 11 ehil&en ehil&en NNP cord-005646-xhx9pzhj 3787 12 heos heos NNP cord-005646-xhx9pzhj 3787 13 suecessthl suecessthl NNP cord-005646-xhx9pzhj 3787 14 outcome outcome NN cord-005646-xhx9pzhj 3787 15 , , , cord-005646-xhx9pzhj 3787 16 without without IN cord-005646-xhx9pzhj 3787 17 S S NNP cord-005646-xhx9pzhj 3787 18 ~ ~ CD cord-005646-xhx9pzhj 3787 19 lllens lllen NNS cord-005646-xhx9pzhj 3787 20 , , , cord-005646-xhx9pzhj 3787 21 instead instead RB cord-005646-xhx9pzhj 3787 22 they -PRON- PRP cord-005646-xhx9pzhj 3787 23 had have VBD cord-005646-xhx9pzhj 3787 24 been be VBN cord-005646-xhx9pzhj 3787 25 tremted tremte VBN cord-005646-xhx9pzhj 3787 26 in in IN cord-005646-xhx9pzhj 3787 27 limited limited JJ cord-005646-xhx9pzhj 3787 28 conditions condition NNS cord-005646-xhx9pzhj 3787 29 . . . cord-005646-xhx9pzhj 3787 30 ' ' '' cord-005646-xhx9pzhj 3787 31 ] ] -RRB- cord-005646-xhx9pzhj 3787 32 ' ' '' cord-005646-xhx9pzhj 3788 1 he -PRON- PRP cord-005646-xhx9pzhj 3788 2 rest rest NN cord-005646-xhx9pzhj 3788 3 of of IN cord-005646-xhx9pzhj 3788 4 our -PRON- PRP$ cord-005646-xhx9pzhj 3788 5 patients patient NNS cord-005646-xhx9pzhj 3788 6 were be VBD cord-005646-xhx9pzhj 3788 7 previously previously RB cord-005646-xhx9pzhj 3788 8 diagnosed diagnose VBN cord-005646-xhx9pzhj 3788 9 ~s ~s NNP cord-005646-xhx9pzhj 3788 10 ettronie ettronie NNP cord-005646-xhx9pzhj 3788 11 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3788 12 patients patient NNS cord-005646-xhx9pzhj 3788 13 , , , cord-005646-xhx9pzhj 3788 14 with with IN cord-005646-xhx9pzhj 3788 15 high high JJ cord-005646-xhx9pzhj 3788 16 risk risk NN cord-005646-xhx9pzhj 3788 17 score score NN cord-005646-xhx9pzhj 3788 18 system system NN cord-005646-xhx9pzhj 3788 19 ibr ibr NN cord-005646-xhx9pzhj 3788 20 having have VBG cord-005646-xhx9pzhj 3788 21 seqnells seqnell NNS cord-005646-xhx9pzhj 3788 22 ' ' POS cord-005646-xhx9pzhj 3788 23 llae llae NNS cord-005646-xhx9pzhj 3788 24 mortality mortality NN cord-005646-xhx9pzhj 3788 25 rate rate NN cord-005646-xhx9pzhj 3788 26 were be VBD cord-005646-xhx9pzhj 3788 27 0,5 0,5 CD cord-005646-xhx9pzhj 3788 28 % % NN cord-005646-xhx9pzhj 3788 29 . . . cord-005646-xhx9pzhj 3789 1 The the DT cord-005646-xhx9pzhj 3789 2 continuous continuous JJ cord-005646-xhx9pzhj 3789 3 blood blood NN cord-005646-xhx9pzhj 3789 4 gas gas NN cord-005646-xhx9pzhj 3789 5 monitor monitor NN cord-005646-xhx9pzhj 3789 6 , , , cord-005646-xhx9pzhj 3789 7 Pasatrend Pasatrend NNP cord-005646-xhx9pzhj 3789 8 7 7 CD cord-005646-xhx9pzhj 3790 1 ( ( -LRB- cord-005646-xhx9pzhj 3790 2 Biomedical Biomedical NNP cord-005646-xhx9pzhj 3790 3 Sensors Sensors NNPS cord-005646-xhx9pzhj 3790 4 , , , cord-005646-xhx9pzhj 3790 5 Ltd. Ltd. NNP cord-005646-xhx9pzhj 3790 6 , , , cord-005646-xhx9pzhj 3790 7 High High NNP cord-005646-xhx9pzhj 3790 8 Wycombe Wycombe NNP cord-005646-xhx9pzhj 3790 9 , , , cord-005646-xhx9pzhj 3790 10 Bucks Bucks NNP cord-005646-xhx9pzhj 3790 11 , , , cord-005646-xhx9pzhj 3790 12 England England NNP cord-005646-xhx9pzhj 3790 13 ) ) -RRB- cord-005646-xhx9pzhj 3790 14 has have VBZ cord-005646-xhx9pzhj 3790 15 the the DT cord-005646-xhx9pzhj 3790 16 capability capability NN cord-005646-xhx9pzhj 3790 17 of of IN cord-005646-xhx9pzhj 3790 18 measuring measure VBG cord-005646-xhx9pzhj 3790 19 pH pH NNP cord-005646-xhx9pzhj 3790 20 , , , cord-005646-xhx9pzhj 3790 21 pCO2 pCO2 NNP cord-005646-xhx9pzhj 3790 22 , , , cord-005646-xhx9pzhj 3790 23 and and CC cord-005646-xhx9pzhj 3790 24 pO2 pO2 NNP cord-005646-xhx9pzhj 3790 25 via via IN cord-005646-xhx9pzhj 3790 26 an an DT cord-005646-xhx9pzhj 3790 27 indwelling indwell VBG cord-005646-xhx9pzhj 3790 28 optical optical JJ cord-005646-xhx9pzhj 3790 29 absorption absorption NN cord-005646-xhx9pzhj 3790 30 optodelClark optodelclark NN cord-005646-xhx9pzhj 3790 31 electrode electrode NN cord-005646-xhx9pzhj 3790 32 sensor sensor NN cord-005646-xhx9pzhj 3790 33 that that WDT cord-005646-xhx9pzhj 3790 34 is be VBZ cord-005646-xhx9pzhj 3790 35 placed place VBN cord-005646-xhx9pzhj 3790 36 through through IN cord-005646-xhx9pzhj 3790 37 an an DT cord-005646-xhx9pzhj 3790 38 intra intra JJ cord-005646-xhx9pzhj 3790 39 - - JJ cord-005646-xhx9pzhj 3790 40 arterial arterial JJ cord-005646-xhx9pzhj 3790 41 catheter catheter NN cord-005646-xhx9pzhj 3790 42 . . . cord-005646-xhx9pzhj 3791 1 We -PRON- PRP cord-005646-xhx9pzhj 3791 2 evaluated evaluate VBD cord-005646-xhx9pzhj 3791 3 the the DT cord-005646-xhx9pzhj 3791 4 accuracy accuracy NN cord-005646-xhx9pzhj 3791 5 of of IN cord-005646-xhx9pzhj 3791 6 the the DT cord-005646-xhx9pzhj 3791 7 sensor sensor NN cord-005646-xhx9pzhj 3791 8 in in IN cord-005646-xhx9pzhj 3791 9 radial radial JJ cord-005646-xhx9pzhj 3791 10 and and CC cord-005646-xhx9pzhj 3791 11 femoral femoral JJ cord-005646-xhx9pzhj 3791 12 locations location NNS cord-005646-xhx9pzhj 3791 13 in in IN cord-005646-xhx9pzhj 3791 14 critically critically RB cord-005646-xhx9pzhj 3791 15 ill ill JJ cord-005646-xhx9pzhj 3791 16 pediatric pediatric JJ cord-005646-xhx9pzhj 3791 17 patients patient NNS cord-005646-xhx9pzhj 3791 18 . . . cord-005646-xhx9pzhj 3792 1 Methods method NNS cord-005646-xhx9pzhj 3792 2 : : : cord-005646-xhx9pzhj 3793 1 The the DT cord-005646-xhx9pzhj 3793 2 simultaneous simultaneous JJ cord-005646-xhx9pzhj 3793 3 values value NNS cord-005646-xhx9pzhj 3793 4 of of IN cord-005646-xhx9pzhj 3793 5 pH pH NNP cord-005646-xhx9pzhj 3793 6 , , , cord-005646-xhx9pzhj 3793 7 pCOz pcoz XX cord-005646-xhx9pzhj 3793 8 , , , cord-005646-xhx9pzhj 3793 9 and and CC cord-005646-xhx9pzhj 3793 10 pO2 pO2 NNP cord-005646-xhx9pzhj 3793 11 recorded record VBN cord-005646-xhx9pzhj 3793 12 from from IN cord-005646-xhx9pzhj 3793 13 the the DT cord-005646-xhx9pzhj 3793 14 Paratrend Paratrend NNP cord-005646-xhx9pzhj 3793 15 7 7 CD cord-005646-xhx9pzhj 3793 16 monitor monitor NN cord-005646-xhx9pzhj 3793 17 were be VBD cord-005646-xhx9pzhj 3793 18 compared compare VBN cord-005646-xhx9pzhj 3793 19 to to IN cord-005646-xhx9pzhj 3793 20 values value NNS cord-005646-xhx9pzhj 3793 21 measured measure VBN cord-005646-xhx9pzhj 3793 22 by by IN cord-005646-xhx9pzhj 3793 23 standard standard JJ cord-005646-xhx9pzhj 3793 24 arterial arterial JJ cord-005646-xhx9pzhj 3793 25 blood blood NN cord-005646-xhx9pzhj 3793 26 gas gas NN cord-005646-xhx9pzhj 3793 27 analyzer analyzer NN cord-005646-xhx9pzhj 3793 28 ( ( -LRB- cord-005646-xhx9pzhj 3793 29 Coming come VBG cord-005646-xhx9pzhj 3793 30 278 278 CD cord-005646-xhx9pzhj 3793 31 , , , cord-005646-xhx9pzhj 3793 32 Ciba Ciba NNP cord-005646-xhx9pzhj 3793 33 - - HYPH cord-005646-xhx9pzhj 3793 34 Corning Corning NNP cord-005646-xhx9pzhj 3793 35 Diagnostics Diagnostics NNPS cord-005646-xhx9pzhj 3793 36 , , , cord-005646-xhx9pzhj 3793 37 Medfield Medfield NNP cord-005646-xhx9pzhj 3793 38 , , , cord-005646-xhx9pzhj 3793 39 MA MA NNP cord-005646-xhx9pzhj 3793 40 ) ) -RRB- cord-005646-xhx9pzhj 3793 41 . . . cord-005646-xhx9pzhj 3794 1 Criteria criterion NNS cord-005646-xhx9pzhj 3794 2 for for IN cord-005646-xhx9pzhj 3794 3 the the DT cord-005646-xhx9pzhj 3794 4 elimination elimination NN cord-005646-xhx9pzhj 3794 5 of of IN cord-005646-xhx9pzhj 3794 6 data datum NNS cord-005646-xhx9pzhj 3794 7 points point NNS cord-005646-xhx9pzhj 3794 8 included include VBD cord-005646-xhx9pzhj 3794 9 a a DT cord-005646-xhx9pzhj 3794 10 core core NN cord-005646-xhx9pzhj 3794 11 vs. vs. IN cord-005646-xhx9pzhj 3794 12 sensor sensor NN cord-005646-xhx9pzhj 3794 13 temp temp NN cord-005646-xhx9pzhj 3794 14 . . . cord-005646-xhx9pzhj 3795 1 gradient gradient NN cord-005646-xhx9pzhj 3795 2 , , , cord-005646-xhx9pzhj 3795 3 and and CC cord-005646-xhx9pzhj 3795 4 sensor sensor NN cord-005646-xhx9pzhj 3795 5 pulled pull VBD cord-005646-xhx9pzhj 3795 6 back back RB cord-005646-xhx9pzhj 3795 7 beyond beyond IN cord-005646-xhx9pzhj 3795 8 accepted accepted JJ cord-005646-xhx9pzhj 3795 9 insertion insertion NN cord-005646-xhx9pzhj 3795 10 distance distance NN cord-005646-xhx9pzhj 3795 11 . . . cord-005646-xhx9pzhj 3796 1 Mean mean JJ cord-005646-xhx9pzhj 3796 2 time time NN cord-005646-xhx9pzhj 3796 3 of of IN cord-005646-xhx9pzhj 3796 4 monitoring monitoring NN cord-005646-xhx9pzhj 3796 5 per per IN cord-005646-xhx9pzhj 3796 6 sensor sensor NN cord-005646-xhx9pzhj 3796 7 was be VBD cord-005646-xhx9pzhj 3796 8 108 108 CD cord-005646-xhx9pzhj 3796 9 hours hour NNS cord-005646-xhx9pzhj 3797 1 ( ( -LRB- cord-005646-xhx9pzhj 3797 2 range range VBP cord-005646-xhx9pzhj 3797 3 0.75 0.75 CD cord-005646-xhx9pzhj 3797 4 - - HYPH cord-005646-xhx9pzhj 3797 5 403.7 403.7 CD cord-005646-xhx9pzhj 3797 6 hrs hrs NN cord-005646-xhx9pzhj 3797 7 ) ) -RRB- cord-005646-xhx9pzhj 3797 8 . . . cord-005646-xhx9pzhj 3798 1 Mean mean JJ cord-005646-xhx9pzhj 3798 2 time time NN cord-005646-xhx9pzhj 3798 3 of of IN cord-005646-xhx9pzhj 3798 4 radial radial JJ cord-005646-xhx9pzhj 3798 5 monitoring monitoring NN cord-005646-xhx9pzhj 3798 6 was be VBD cord-005646-xhx9pzhj 3798 7 35 35 CD cord-005646-xhx9pzhj 3798 8 hrs hrs NN cord-005646-xhx9pzhj 3798 9 ( ( -LRB- cord-005646-xhx9pzhj 3798 10 range range VBP cord-005646-xhx9pzhj 3798 11 0.75 0.75 CD cord-005646-xhx9pzhj 3798 12 - - HYPH cord-005646-xhx9pzhj 3798 13 160.5hrs 160.5hrs CD cord-005646-xhx9pzhj 3798 14 ) ) -RRB- cord-005646-xhx9pzhj 3798 15 and and CC cord-005646-xhx9pzhj 3798 16 of of IN cord-005646-xhx9pzhj 3798 17 femoral femoral JJ cord-005646-xhx9pzhj 3798 18 monitoring monitoring NN cord-005646-xhx9pzhj 3798 19 was be VBD cord-005646-xhx9pzhj 3798 20 137.2 137.2 CD cord-005646-xhx9pzhj 3798 21 hrs hrs NN cord-005646-xhx9pzhj 3798 22 ( ( -LRB- cord-005646-xhx9pzhj 3798 23 range range VBP cord-005646-xhx9pzhj 3798 24 12.8 12.8 CD cord-005646-xhx9pzhj 3798 25 - - HYPH cord-005646-xhx9pzhj 3798 26 403.7 403.7 CD cord-005646-xhx9pzhj 3798 27 hrs hrs NN cord-005646-xhx9pzhj 3798 28 . . . cord-005646-xhx9pzhj 3798 29 ) ) -RRB- cord-005646-xhx9pzhj 3798 30 . . . cord-005646-xhx9pzhj 3799 1 Linear linear JJ cord-005646-xhx9pzhj 3799 2 regression regression NN cord-005646-xhx9pzhj 3799 3 and and CC cord-005646-xhx9pzhj 3799 4 Bland Bland NNP cord-005646-xhx9pzhj 3799 5 - - HYPH cord-005646-xhx9pzhj 3799 6 Altman Altman NNP cord-005646-xhx9pzhj 3800 1 analysis analysis NN cord-005646-xhx9pzhj 3800 2 for for IN cord-005646-xhx9pzhj 3800 3 bias bias NN cord-005646-xhx9pzhj 3800 4 and and CC cord-005646-xhx9pzhj 3800 5 precision precision NN cord-005646-xhx9pzhj 3800 6 for for IN cord-005646-xhx9pzhj 3800 7 each each DT cord-005646-xhx9pzhj 3800 8 parameter parameter NN cord-005646-xhx9pzhj 3800 9 were be VBD cord-005646-xhx9pzhj 3800 10 calculated calculate VBN cord-005646-xhx9pzhj 3800 11 . . . cord-005646-xhx9pzhj 3801 1 Results result NNS cord-005646-xhx9pzhj 3801 2 : : : cord-005646-xhx9pzhj 3802 1 A a DT cord-005646-xhx9pzhj 3802 2 total total NN cord-005646-xhx9pzhj 3802 3 of of IN cord-005646-xhx9pzhj 3802 4 49 49 CD cord-005646-xhx9pzhj 3802 5 patients patient NNS cord-005646-xhx9pzhj 3802 6 ( ( -LRB- cord-005646-xhx9pzhj 3802 7 age age NN cord-005646-xhx9pzhj 3802 8 range range NN cord-005646-xhx9pzhj 3802 9 2 2 CD cord-005646-xhx9pzhj 3802 10 weeks week NNS cord-005646-xhx9pzhj 3802 11 to to IN cord-005646-xhx9pzhj 3802 12 18 18 CD cord-005646-xhx9pzhj 3802 13 years year NNS cord-005646-xhx9pzhj 3802 14 ) ) -RRB- cord-005646-xhx9pzhj 3802 15 had have VBD cord-005646-xhx9pzhj 3802 16 paired pair VBN cord-005646-xhx9pzhj 3802 17 samples sample NNS cord-005646-xhx9pzhj 3802 18 of of IN cord-005646-xhx9pzhj 3802 19 pH ph NN cord-005646-xhx9pzhj 3802 20 , , , cord-005646-xhx9pzhj 3802 21 pens pen NNS cord-005646-xhx9pzhj 3802 22 , , , cord-005646-xhx9pzhj 3802 23 and and CC cord-005646-xhx9pzhj 3802 24 pOz poz NN cord-005646-xhx9pzhj 3802 25 made make VBN cord-005646-xhx9pzhj 3802 26 by by IN cord-005646-xhx9pzhj 3802 27 the the DT cord-005646-xhx9pzhj 3802 28 sensor sensor NN cord-005646-xhx9pzhj 3802 29 and and CC cord-005646-xhx9pzhj 3802 30 blood blood NN cord-005646-xhx9pzhj 3802 31 g&s g&s NNP cord-005646-xhx9pzhj 3802 32 analyzer analyzer NN cord-005646-xhx9pzhj 3802 33 . . . cord-005646-xhx9pzhj 3803 1 The the DT cord-005646-xhx9pzhj 3803 2 range range NN cord-005646-xhx9pzhj 3803 3 of of IN cord-005646-xhx9pzhj 3803 4 measurements measurement NNS cord-005646-xhx9pzhj 3803 5 were be VBD cord-005646-xhx9pzhj 3803 6 pH pH NNP cord-005646-xhx9pzhj 3803 7 6.99 6.99 CD cord-005646-xhx9pzhj 3803 8 - - HYPH cord-005646-xhx9pzhj 3803 9 7.66 7.66 CD cord-005646-xhx9pzhj 3803 10 , , , cord-005646-xhx9pzhj 3803 11 pCO pco CD cord-005646-xhx9pzhj 3803 12 , , , cord-005646-xhx9pzhj 3803 13 16.0-I14.2 16.0-i14.2 CD cord-005646-xhx9pzhj 3803 14 t(n t(n NNP cord-005646-xhx9pzhj 3803 15 r r NN cord-005646-xhx9pzhj 3803 16 , , , cord-005646-xhx9pzhj 3803 17 and and CC cord-005646-xhx9pzhj 3803 18 pO2 pO2 NNP cord-005646-xhx9pzhj 3803 19 34 34 CD cord-005646-xhx9pzhj 3803 20 - - SYM cord-005646-xhx9pzhj 3803 21 480 480 CD cord-005646-xhx9pzhj 3803 22 torr torr NN cord-005646-xhx9pzhj 3803 23 . . . cord-005646-xhx9pzhj 3803 24 _SP cord-005646-xhx9pzhj 3804 1 The the DT cord-005646-xhx9pzhj 3804 2 Paratrend Paratrend NNP cord-005646-xhx9pzhj 3804 3 7 7 CD cord-005646-xhx9pzhj 3804 4 monitor monitor NN cord-005646-xhx9pzhj 3804 5 demonstrated demonstrate VBD cord-005646-xhx9pzhj 3804 6 accuracy accuracy NN cord-005646-xhx9pzhj 3804 7 that that WDT cord-005646-xhx9pzhj 3804 8 is be VBZ cord-005646-xhx9pzhj 3804 9 comparable comparable JJ cord-005646-xhx9pzhj 3804 10 to to IN cord-005646-xhx9pzhj 3804 11 the the DT cord-005646-xhx9pzhj 3804 12 accepted accept VBN cord-005646-xhx9pzhj 3804 13 standard standard NN cord-005646-xhx9pzhj 3804 14 of of IN cord-005646-xhx9pzhj 3804 15 blood blood NN cord-005646-xhx9pzhj 3804 16 gas gas NN cord-005646-xhx9pzhj 3804 17 analysis analysis NN cord-005646-xhx9pzhj 3804 18 in in IN cord-005646-xhx9pzhj 3804 19 a a DT cord-005646-xhx9pzhj 3804 20 group group NN cord-005646-xhx9pzhj 3804 21 of of IN cord-005646-xhx9pzhj 3804 22 critically critically RB cord-005646-xhx9pzhj 3804 23 ill ill JJ cord-005646-xhx9pzhj 3804 24 pediatric pediatric JJ cord-005646-xhx9pzhj 3804 25 patients patient NNS cord-005646-xhx9pzhj 3804 26 manifesting manifest VBG cord-005646-xhx9pzhj 3804 27 wide wide JJ cord-005646-xhx9pzhj 3804 28 variation variation NN cord-005646-xhx9pzhj 3804 29 in in IN cord-005646-xhx9pzhj 3804 30 pH pH NNP cord-005646-xhx9pzhj 3804 31 , , , cord-005646-xhx9pzhj 3804 32 pen2 pen2 XX cord-005646-xhx9pzhj 3804 33 , , , cord-005646-xhx9pzhj 3804 34 and and CC cord-005646-xhx9pzhj 3804 35 pOz poz NN cord-005646-xhx9pzhj 3804 36 .. .. . cord-005646-xhx9pzhj 3805 1 This this DT cord-005646-xhx9pzhj 3805 2 technique technique NN cord-005646-xhx9pzhj 3805 3 appears appear VBZ cord-005646-xhx9pzhj 3805 4 m m PRP cord-005646-xhx9pzhj 3805 5 be be VB cord-005646-xhx9pzhj 3805 6 very very RB cord-005646-xhx9pzhj 3805 7 useful useful JJ cord-005646-xhx9pzhj 3805 8 especially especially RB cord-005646-xhx9pzhj 3805 9 in in IN cord-005646-xhx9pzhj 3805 10 the the DT cord-005646-xhx9pzhj 3805 11 extreme extreme JJ cord-005646-xhx9pzhj 3805 12 values value NNS cord-005646-xhx9pzhj 3805 13 of of IN cord-005646-xhx9pzhj 3805 14 the the DT cord-005646-xhx9pzhj 3805 15 parameters parameter NNS cord-005646-xhx9pzhj 3805 16 measured measure VBN cord-005646-xhx9pzhj 3805 17 . . . cord-005646-xhx9pzhj 3806 1 Funding funding NN cord-005646-xhx9pzhj 3806 2 provided provide VBN cord-005646-xhx9pzhj 3806 3 by by IN cord-005646-xhx9pzhj 3806 4 Biomedical Biomedical NNP cord-005646-xhx9pzhj 3806 5 Sensors Sensors NNPS cord-005646-xhx9pzhj 3806 6 . . . cord-005646-xhx9pzhj 3807 1 UNDERSTANDING understanding NN cord-005646-xhx9pzhj 3807 2 OF of IN cord-005646-xhx9pzhj 3807 3 PULSE PULSE NNP cord-005646-xhx9pzhj 3807 4 OXIMETRY OXIMETRY NNP cord-005646-xhx9pzhj 3807 5 D.SEMPLE D.SEMPLE NNP cord-005646-xhx9pzhj 3807 6 , , , cord-005646-xhx9pzhj 3807 7 L.E.WILSON l.e.wilson NN cord-005646-xhx9pzhj 3807 8 . . . cord-005646-xhx9pzhj 3808 1 Royal Royal NNP cord-005646-xhx9pzhj 3808 2 Hospital Hospital NNP cord-005646-xhx9pzhj 3808 3 for for IN cord-005646-xhx9pzhj 3808 4 Sick Sick NNP cord-005646-xhx9pzhj 3808 5 Children Children NNPS cord-005646-xhx9pzhj 3808 6 , , , cord-005646-xhx9pzhj 3808 7 Edinburgh Edinburgh NNP cord-005646-xhx9pzhj 3808 8 , , , cord-005646-xhx9pzhj 3808 9 EH9 EH9 NNP cord-005646-xhx9pzhj 3808 10 1LF 1lf CD cord-005646-xhx9pzhj 3808 11 , , , cord-005646-xhx9pzhj 3808 12 Scotland Scotland NNP cord-005646-xhx9pzhj 3808 13 , , , cord-005646-xhx9pzhj 3808 14 UK UK NNP cord-005646-xhx9pzhj 3808 15 . . . cord-005646-xhx9pzhj 3809 1 Pulse pulse NN cord-005646-xhx9pzhj 3809 2 oximetry oximetry NN cord-005646-xhx9pzhj 3809 3 is be VBZ cord-005646-xhx9pzhj 3809 4 a a DT cord-005646-xhx9pzhj 3809 5 useful useful JJ cord-005646-xhx9pzhj 3809 6 , , , cord-005646-xhx9pzhj 3809 7 non non JJ cord-005646-xhx9pzhj 3809 8 - - JJ cord-005646-xhx9pzhj 3809 9 invasive invasive JJ cord-005646-xhx9pzhj 3809 10 monitor monitor NN cord-005646-xhx9pzhj 3809 11 , , , cord-005646-xhx9pzhj 3809 12 routinely routinely RB cord-005646-xhx9pzhj 3809 13 used use VBN cord-005646-xhx9pzhj 3809 14 on on IN cord-005646-xhx9pzhj 3809 15 the the DT cord-005646-xhx9pzhj 3809 16 ITU ITU NNP cord-005646-xhx9pzhj 3809 17 and and CC cord-005646-xhx9pzhj 3809 18 increasingly increasingly RB cord-005646-xhx9pzhj 3809 19 often often RB cord-005646-xhx9pzhj 3809 20 on on IN cord-005646-xhx9pzhj 3809 21 the the DT cord-005646-xhx9pzhj 3809 22 general general JJ cord-005646-xhx9pzhj 3809 23 wards ward NNS cord-005646-xhx9pzhj 3809 24 . . . cord-005646-xhx9pzhj 3810 1 We -PRON- PRP cord-005646-xhx9pzhj 3810 2 used use VBD cord-005646-xhx9pzhj 3810 3 a a DT cord-005646-xhx9pzhj 3810 4 questionnaire questionnaire NN cord-005646-xhx9pzhj 3810 5 incorporating incorporate VBG cord-005646-xhx9pzhj 3810 6 questions question NNS cord-005646-xhx9pzhj 3810 7 on on IN cord-005646-xhx9pzhj 3810 8 the the DT cord-005646-xhx9pzhj 3810 9 theory theory NN cord-005646-xhx9pzhj 3810 10 and and CC cord-005646-xhx9pzhj 3810 11 clinical clinical JJ cord-005646-xhx9pzhj 3810 12 uses use NNS cord-005646-xhx9pzhj 3810 13 of of IN cord-005646-xhx9pzhj 3810 14 the the DT cord-005646-xhx9pzhj 3810 15 pulse pulse NN cord-005646-xhx9pzhj 3810 16 oximeter oximeter NN cord-005646-xhx9pzhj 3810 17 to to TO cord-005646-xhx9pzhj 3810 18 assess assess VB cord-005646-xhx9pzhj 3810 19 understanding understanding NN cord-005646-xhx9pzhj 3810 20 of of IN cord-005646-xhx9pzhj 3810 21 pulse pulse NN cord-005646-xhx9pzhj 3810 22 oximetry oximetry NN cord-005646-xhx9pzhj 3810 23 in in IN cord-005646-xhx9pzhj 3811 1 medical medical JJ cord-005646-xhx9pzhj 3811 2 and and CC cord-005646-xhx9pzhj 3811 3 paramedical paramedical JJ cord-005646-xhx9pzhj 3811 4 staff staff NN cord-005646-xhx9pzhj 3811 5 Doctors doctor NNS cord-005646-xhx9pzhj 3811 6 indicated indicate VBD cord-005646-xhx9pzhj 3811 7 grade grade NN cord-005646-xhx9pzhj 3811 8 , , , cord-005646-xhx9pzhj 3811 9 speciality speciality NN cord-005646-xhx9pzhj 3811 10 , , , cord-005646-xhx9pzhj 3811 11 pulse pulse NN cord-005646-xhx9pzhj 3811 12 oximetry oximetry NN cord-005646-xhx9pzhj 3811 13 tuition tuition NN cord-005646-xhx9pzhj 3811 14 and and CC cord-005646-xhx9pzhj 3811 15 neonatology neonatology NN cord-005646-xhx9pzhj 3811 16 experience experience NN cord-005646-xhx9pzhj 3811 17 . . . cord-005646-xhx9pzhj 3812 1 45 45 CD cord-005646-xhx9pzhj 3812 2 doctors doctor NNS cord-005646-xhx9pzhj 3812 3 , , , cord-005646-xhx9pzhj 3812 4 15 15 CD cord-005646-xhx9pzhj 3812 5 ITU ITU NNP cord-005646-xhx9pzhj 3812 6 nurses nurse NNS cord-005646-xhx9pzhj 3812 7 , , , cord-005646-xhx9pzhj 3812 8 t9 t9 VB cord-005646-xhx9pzhj 3812 9 medical medical JJ cord-005646-xhx9pzhj 3812 10 students student NNS cord-005646-xhx9pzhj 3812 11 and and CC cord-005646-xhx9pzhj 3812 12 4 4 CD cord-005646-xhx9pzhj 3812 13 physiotherapists physiotherapist NNS cord-005646-xhx9pzhj 3812 14 completed complete VBD cord-005646-xhx9pzhj 3812 15 the the DT cord-005646-xhx9pzhj 3812 16 questionnaire questionnaire NN cord-005646-xhx9pzhj 3812 17 . . . cord-005646-xhx9pzhj 3813 1 Some some DT cord-005646-xhx9pzhj 3813 2 confusion confusion NN cord-005646-xhx9pzhj 3813 3 existed exist VBD cord-005646-xhx9pzhj 3813 4 between between IN cord-005646-xhx9pzhj 3813 5 the the DT cord-005646-xhx9pzhj 3813 6 principles principle NNS cord-005646-xhx9pzhj 3813 7 of of IN cord-005646-xhx9pzhj 3813 8 pulse pulse NN cord-005646-xhx9pzhj 3813 9 oximetry oximetry NN cord-005646-xhx9pzhj 3813 10 and and CC cord-005646-xhx9pzhj 3813 11 transcutaneous transcutaneous JJ cord-005646-xhx9pzhj 3813 12 oxygen oxygen NN cord-005646-xhx9pzhj 3813 13 measurement measurement NN cord-005646-xhx9pzhj 3813 14 . . . cord-005646-xhx9pzhj 3814 1 Wide wide JJ cord-005646-xhx9pzhj 3814 2 variations variation NNS cord-005646-xhx9pzhj 3814 3 in in IN cord-005646-xhx9pzhj 3814 4 the the DT cord-005646-xhx9pzhj 3814 5 lowest low JJS cord-005646-xhx9pzhj 3814 6 acceptable acceptable JJ cord-005646-xhx9pzhj 3814 7 saturation saturation NN cord-005646-xhx9pzhj 3814 8 in in IN cord-005646-xhx9pzhj 3814 9 fit fit JJ cord-005646-xhx9pzhj 3814 10 children child NNS cord-005646-xhx9pzhj 3814 11 were be VBD cord-005646-xhx9pzhj 3814 12 seen see VBN cord-005646-xhx9pzhj 3814 13 ( ( -LRB- cord-005646-xhx9pzhj 3814 14 80 80 CD cord-005646-xhx9pzhj 3814 15 - - SYM cord-005646-xhx9pzhj 3814 16 95 95 CD cord-005646-xhx9pzhj 3814 17 % % NN cord-005646-xhx9pzhj 3814 18 ) ) -RRB- cord-005646-xhx9pzhj 3814 19 , , , cord-005646-xhx9pzhj 3814 20 with with IN cord-005646-xhx9pzhj 3814 21 around around RB cord-005646-xhx9pzhj 3814 22 20 20 CD cord-005646-xhx9pzhj 3814 23 % % NN cord-005646-xhx9pzhj 3814 24 of of IN cord-005646-xhx9pzhj 3814 25 respondents respondent NNS cord-005646-xhx9pzhj 3814 26 in in IN cord-005646-xhx9pzhj 3814 27 all all DT cord-005646-xhx9pzhj 3814 28 groups group NNS cord-005646-xhx9pzhj 3814 29 accepting accept VBG cord-005646-xhx9pzhj 3814 30 values value NNS cord-005646-xhx9pzhj 3814 31 of of IN cord-005646-xhx9pzhj 3814 32 90 90 CD cord-005646-xhx9pzhj 3814 33 % % NN cord-005646-xhx9pzhj 3814 34 or or CC cord-005646-xhx9pzhj 3814 35 less less JJR cord-005646-xhx9pzhj 3814 36 . . . cord-005646-xhx9pzhj 3815 1 Some some DT cord-005646-xhx9pzhj 3815 2 potentially potentially RB cord-005646-xhx9pzhj 3815 3 serious serious JJ cord-005646-xhx9pzhj 3815 4 mistakes mistake NNS cord-005646-xhx9pzhj 3815 5 were be VBD cord-005646-xhx9pzhj 3815 6 made make VBN cord-005646-xhx9pzhj 3815 7 in in IN cord-005646-xhx9pzhj 3815 8 the the DT cord-005646-xhx9pzhj 3815 9 evaluation evaluation NN cord-005646-xhx9pzhj 3815 10 of of IN cord-005646-xhx9pzhj 3815 11 oxygen oxygen NN cord-005646-xhx9pzhj 3815 12 saturations saturation NNS cord-005646-xhx9pzhj 3815 13 in in IN cord-005646-xhx9pzhj 3815 14 the the DT cord-005646-xhx9pzhj 3815 15 clinical clinical JJ cord-005646-xhx9pzhj 3815 16 scenarios scenario NNS cord-005646-xhx9pzhj 3815 17 . . . cord-005646-xhx9pzhj 3816 1 There there EX cord-005646-xhx9pzhj 3816 2 were be VBD cord-005646-xhx9pzhj 3816 3 widespread widespread JJ cord-005646-xhx9pzhj 3816 4 variations variation NNS cord-005646-xhx9pzhj 3816 5 in in IN cord-005646-xhx9pzhj 3816 6 correct correct JJ cord-005646-xhx9pzhj 3816 7 responses response NNS cord-005646-xhx9pzhj 3816 8 at at IN cord-005646-xhx9pzhj 3816 9 all all DT cord-005646-xhx9pzhj 3816 10 grades grade NNS cord-005646-xhx9pzhj 3816 11 of of IN cord-005646-xhx9pzhj 3816 12 medical medical JJ cord-005646-xhx9pzhj 3816 13 staffing staffing NN cord-005646-xhx9pzhj 3816 14 . . . cord-005646-xhx9pzhj 3817 1 Nurses nurse NNS cord-005646-xhx9pzhj 3817 2 scored score VBD cord-005646-xhx9pzhj 3817 3 well well RB cord-005646-xhx9pzhj 3817 4 on on IN cord-005646-xhx9pzhj 3817 5 more more RBR cord-005646-xhx9pzhj 3817 6 clinically clinically RB cord-005646-xhx9pzhj 3817 7 - - HYPH cord-005646-xhx9pzhj 3817 8 orientated orientated JJ cord-005646-xhx9pzhj 3817 9 questions question NNS cord-005646-xhx9pzhj 3817 10 but but CC cord-005646-xhx9pzhj 3817 11 relatively relatively RB cord-005646-xhx9pzhj 3817 12 poorly poorly RB cord-005646-xhx9pzhj 3817 13 on on IN cord-005646-xhx9pzhj 3817 14 theory theory NN cord-005646-xhx9pzhj 3817 15 . . . cord-005646-xhx9pzhj 3818 1 Only only RB cord-005646-xhx9pzhj 3818 2 15 15 CD cord-005646-xhx9pzhj 3818 3 % % NN cord-005646-xhx9pzhj 3818 4 of of IN cord-005646-xhx9pzhj 3818 5 doctors doctor NNS cord-005646-xhx9pzhj 3818 6 ( ( -LRB- cord-005646-xhx9pzhj 3818 7 mostly mostly RB cord-005646-xhx9pzhj 3818 8 senior senior JJ cord-005646-xhx9pzhj 3818 9 grades grade NNS cord-005646-xhx9pzhj 3818 10 ) ) -RRB- cord-005646-xhx9pzhj 3818 11 had have VBD cord-005646-xhx9pzhj 3818 12 received receive VBN cord-005646-xhx9pzhj 3818 13 tuition tuition NN cord-005646-xhx9pzhj 3818 14 in in IN cord-005646-xhx9pzhj 3818 15 putse putse NN cord-005646-xhx9pzhj 3818 16 oximetry oximetry NN cord-005646-xhx9pzhj 3818 17 . . . cord-005646-xhx9pzhj 3819 1 Neonatology Neonatology NNP cord-005646-xhx9pzhj 3819 2 rotations rotation NNS cord-005646-xhx9pzhj 3819 3 appeared appear VBD cord-005646-xhx9pzhj 3819 4 to to TO cord-005646-xhx9pzhj 3819 5 confer confer VB cord-005646-xhx9pzhj 3819 6 little little JJ cord-005646-xhx9pzhj 3819 7 additional additional JJ cord-005646-xhx9pzhj 3819 8 knowledge knowledge NN cord-005646-xhx9pzhj 3819 9 on on IN cord-005646-xhx9pzhj 3819 10 pulse pulse NN cord-005646-xhx9pzhj 3819 11 oximetry oximetry NN cord-005646-xhx9pzhj 3819 12 . . . cord-005646-xhx9pzhj 3820 1 Few few JJ cord-005646-xhx9pzhj 3820 2 doctors doctor NNS cord-005646-xhx9pzhj 3820 3 and and CC cord-005646-xhx9pzhj 3820 4 nurses nurse NNS cord-005646-xhx9pzhj 3820 5 receive receive VBP cord-005646-xhx9pzhj 3820 6 tuition tuition NN cord-005646-xhx9pzhj 3820 7 in in IN cord-005646-xhx9pzhj 3820 8 the the DT cord-005646-xhx9pzhj 3820 9 use use NN cord-005646-xhx9pzhj 3820 10 of of IN cord-005646-xhx9pzhj 3820 11 pulse pulse NN cord-005646-xhx9pzhj 3820 12 oximetry oximetry NN cord-005646-xhx9pzhj 3821 1 A a DT cord-005646-xhx9pzhj 3821 2 significant significant JJ cord-005646-xhx9pzhj 3821 3 proportion proportion NN cord-005646-xhx9pzhj 3821 4 of of IN cord-005646-xhx9pzhj 3821 5 nurses nurse NNS cord-005646-xhx9pzhj 3821 6 and and CC cord-005646-xhx9pzhj 3821 7 doctors doctor NNS cord-005646-xhx9pzhj 3821 8 , , , cord-005646-xhx9pzhj 3821 9 of of IN cord-005646-xhx9pzhj 3821 10 all all DT cord-005646-xhx9pzhj 3821 11 grades grade NNS cord-005646-xhx9pzhj 3821 12 , , , cord-005646-xhx9pzhj 3821 13 exhibited exhibit VBD cord-005646-xhx9pzhj 3821 14 a a DT cord-005646-xhx9pzhj 3821 15 lack lack NN cord-005646-xhx9pzhj 3821 16 o o NN cord-005646-xhx9pzhj 3821 17 { { -LRB- cord-005646-xhx9pzhj 3821 18 " " `` cord-005646-xhx9pzhj 3821 19 understanding understanding NN cord-005646-xhx9pzhj 3821 20 of of IN cord-005646-xhx9pzhj 3821 21 the the DT cord-005646-xhx9pzhj 3821 22 principles principle NNS cord-005646-xhx9pzhj 3821 23 of of IN cord-005646-xhx9pzhj 3821 24 pulse pulse NN cord-005646-xhx9pzhj 3821 25 oximetry oximetry NN cord-005646-xhx9pzhj 3821 26 . . . cord-005646-xhx9pzhj 3822 1 This this DT cord-005646-xhx9pzhj 3822 2 may may MD cord-005646-xhx9pzhj 3822 3 result result VB cord-005646-xhx9pzhj 3822 4 in in IN cord-005646-xhx9pzhj 3822 5 unsafe unsafe JJ cord-005646-xhx9pzhj 3822 6 use use NN cord-005646-xhx9pzhj 3822 7 of of IN cord-005646-xhx9pzhj 3822 8 the the DT cord-005646-xhx9pzhj 3822 9 equipment equipment NN cord-005646-xhx9pzhj 3822 10 and and CC cord-005646-xhx9pzhj 3822 11 put put VB cord-005646-xhx9pzhj 3822 12 patients patient NNS cord-005646-xhx9pzhj 3822 13 at at IN cord-005646-xhx9pzhj 3822 14 risk risk NN cord-005646-xhx9pzhj 3822 15 . . . cord-005646-xhx9pzhj 3823 1 One one PRP cord-005646-xhx9pzhj 3823 2 can can MD cord-005646-xhx9pzhj 3823 3 see see VB cord-005646-xhx9pzhj 3823 4 from from IN cord-005646-xhx9pzhj 3823 5 the the DT cord-005646-xhx9pzhj 3823 6 table table NN cord-005646-xhx9pzhj 3823 7 that that DT cord-005646-xhx9pzhj 3823 8 blood blood NN cord-005646-xhx9pzhj 3823 9 composition composition NN cord-005646-xhx9pzhj 3823 10 in in IN cord-005646-xhx9pzhj 3823 11 Uv Uv NNP cord-005646-xhx9pzhj 3823 12 and and CC cord-005646-xhx9pzhj 3823 13 Ua Ua NNP cord-005646-xhx9pzhj 3823 14 differens differen NNS cord-005646-xhx9pzhj 3823 15 in in IN cord-005646-xhx9pzhj 3823 16 some some DT cord-005646-xhx9pzhj 3823 17 characteristics characteristic NNS cord-005646-xhx9pzhj 3823 18 , , , cord-005646-xhx9pzhj 3823 19 and and CC cord-005646-xhx9pzhj 3823 20 similar similar JJ cord-005646-xhx9pzhj 3823 21 in in IN cord-005646-xhx9pzhj 3823 22 SGP SGP NNP cord-005646-xhx9pzhj 3823 23 magnitude magnitude NN cord-005646-xhx9pzhj 3823 24 . . . cord-005646-xhx9pzhj 3824 1 Venous venous JJ cord-005646-xhx9pzhj 3824 2 - - HYPH cord-005646-xhx9pzhj 3824 3 asterlal asterlal NN cord-005646-xhx9pzhj 3824 4 gradients gradient NNS cord-005646-xhx9pzhj 3824 5 " " '' cord-005646-xhx9pzhj 3824 6 gas gas NN cord-005646-xhx9pzhj 3824 7 functiomals functiomal NNS cord-005646-xhx9pzhj 3824 8 " " '' cord-005646-xhx9pzhj 3824 9 between between IN cord-005646-xhx9pzhj 3824 10 Uv Uv NNP cord-005646-xhx9pzhj 3824 11 and and CC cord-005646-xhx9pzhj 3824 12 Ua Ua NNP cord-005646-xhx9pzhj 3824 13 represent represent VBP cord-005646-xhx9pzhj 3824 14 the the DT cord-005646-xhx9pzhj 3824 15 measure measure NN cord-005646-xhx9pzhj 3824 16 of of IN cord-005646-xhx9pzhj 3824 17 difference difference NN cord-005646-xhx9pzhj 3824 18 in in IN cord-005646-xhx9pzhj 3824 19 this this DT cord-005646-xhx9pzhj 3824 20 characteristics characteristic NNS cord-005646-xhx9pzhj 3824 21 . . . cord-005646-xhx9pzhj 3825 1 The the DT cord-005646-xhx9pzhj 3825 2 gradient gradient NN cord-005646-xhx9pzhj 3825 3 cari cari NNP cord-005646-xhx9pzhj 3825 4 be be VB cord-005646-xhx9pzhj 3825 5 positive positive JJ cord-005646-xhx9pzhj 3825 6 , , , cord-005646-xhx9pzhj 3825 7 zero zero CD cord-005646-xhx9pzhj 3825 8 -order -order NN cord-005646-xhx9pzhj 3825 9 or or CC cord-005646-xhx9pzhj 3825 10 negative negative JJ cord-005646-xhx9pzhj 3825 11 and and CC cord-005646-xhx9pzhj 3825 12 change change VBP cord-005646-xhx9pzhj 3825 13 both both CC cord-005646-xhx9pzhj 3825 14 in in IN cord-005646-xhx9pzhj 3825 15 value value NN cord-005646-xhx9pzhj 3825 16 and and CC cord-005646-xhx9pzhj 3825 17 in in IN cord-005646-xhx9pzhj 3825 18 sign sign NN cord-005646-xhx9pzhj 3825 19 but but CC cord-005646-xhx9pzhj 3825 20 not not RB cord-005646-xhx9pzhj 3825 21 reach reach VB cord-005646-xhx9pzhj 3825 22 APO2 APO2 NNP cord-005646-xhx9pzhj 3825 23 ( ( -LRB- cord-005646-xhx9pzhj 3825 24 positive positive JJ cord-005646-xhx9pzhj 3825 25 ) ) -RRB- cord-005646-xhx9pzhj 3825 26 and and CC cord-005646-xhx9pzhj 3826 1 APCO2 apco2 JJ cord-005646-xhx9pzhj 3826 2 ( ( -LRB- cord-005646-xhx9pzhj 3826 3 negative negative JJ cord-005646-xhx9pzhj 3826 4 ) ) -RRB- cord-005646-xhx9pzhj 3826 5 in in IN cord-005646-xhx9pzhj 3826 6 absolute absolute JJ cord-005646-xhx9pzhj 3826 7 significance significance NN cord-005646-xhx9pzhj 3826 8 . . . cord-005646-xhx9pzhj 3827 1 Minimization minimization NN cord-005646-xhx9pzhj 3827 2 of of IN cord-005646-xhx9pzhj 3827 3 " " `` cord-005646-xhx9pzhj 3827 4 gas gas NN cord-005646-xhx9pzhj 3827 5 functionals functional NNS cord-005646-xhx9pzhj 3827 6 " " '' cord-005646-xhx9pzhj 3827 7 deviations deviation NNS cord-005646-xhx9pzhj 3827 8 atom atom VBP cord-005646-xhx9pzhj 3827 9 the the DT cord-005646-xhx9pzhj 3827 10 zero zero CD cord-005646-xhx9pzhj 3827 11 is be VBZ cord-005646-xhx9pzhj 3827 12 achieved achieve VBN cord-005646-xhx9pzhj 3827 13 due due JJ cord-005646-xhx9pzhj 3827 14 to"mutual to"mutual JJ cord-005646-xhx9pzhj 3827 15 replacement replacement NN cord-005646-xhx9pzhj 3827 16 acts act NNS cord-005646-xhx9pzhj 3827 17 " " '' cord-005646-xhx9pzhj 3827 18 between between IN cord-005646-xhx9pzhj 3827 19 PO2 PO2 NNP cord-005646-xhx9pzhj 3827 20 and and CC cord-005646-xhx9pzhj 3827 21 PCO2 PCO2 NNP cord-005646-xhx9pzhj 3827 22 in in IN cord-005646-xhx9pzhj 3827 23 Uv Uv NNP cord-005646-xhx9pzhj 3827 24 and and CC cord-005646-xhx9pzhj 3827 25 Ua Ua NNP cord-005646-xhx9pzhj 3827 26 blood blood NN cord-005646-xhx9pzhj 3827 27 . . . cord-005646-xhx9pzhj 3828 1 We -PRON- PRP cord-005646-xhx9pzhj 3828 2 suggest suggest VBP cord-005646-xhx9pzhj 3828 3 that that IN cord-005646-xhx9pzhj 3828 4 presented present VBN cord-005646-xhx9pzhj 3828 5 tests test NNS cord-005646-xhx9pzhj 3828 6 can can MD cord-005646-xhx9pzhj 3828 7 be be VB cord-005646-xhx9pzhj 3828 8 useful useful JJ cord-005646-xhx9pzhj 3828 9 in in IN cord-005646-xhx9pzhj 3828 10 full full JJ cord-005646-xhx9pzhj 3828 11 evaluation evaluation NN cord-005646-xhx9pzhj 3828 12 of of IN cord-005646-xhx9pzhj 3828 13 gas gas NN cord-005646-xhx9pzhj 3828 14 exchange exchange NN cord-005646-xhx9pzhj 3828 15 in in IN cord-005646-xhx9pzhj 3828 16 newborns newborn NNS cord-005646-xhx9pzhj 3828 17 . . . cord-005646-xhx9pzhj 3829 1 ( ( -LRB- cord-005646-xhx9pzhj 3829 2 PAP pap NN cord-005646-xhx9pzhj 3829 3 ) ) -RRB- cord-005646-xhx9pzhj 3829 4 in in IN cord-005646-xhx9pzhj 3829 5 the the DT cord-005646-xhx9pzhj 3829 6 context context NN cord-005646-xhx9pzhj 3829 7 of of IN cord-005646-xhx9pzhj 3829 8 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3829 9 hypertension hypertension NN cord-005646-xhx9pzhj 3829 10 is be VBZ cord-005646-xhx9pzhj 3829 11 oft oft RB cord-005646-xhx9pzhj 3829 12 desired desire VBN cord-005646-xhx9pzhj 3829 13 but but CC cord-005646-xhx9pzhj 3829 14 rarely rarely RB cord-005646-xhx9pzhj 3829 15 achieved achieve VBN cord-005646-xhx9pzhj 3829 16 . . . cord-005646-xhx9pzhj 3830 1 inhaled inhale VBN cord-005646-xhx9pzhj 3830 2 nitric nitric NN cord-005646-xhx9pzhj 3830 3 oxide oxide NN cord-005646-xhx9pzhj 3830 4 ( ( -LRB- cord-005646-xhx9pzhj 3830 5 NO no UH cord-005646-xhx9pzhj 3830 6 ) ) -RRB- cord-005646-xhx9pzhj 3830 7 has have VBZ cord-005646-xhx9pzhj 3830 8 been be VBN cord-005646-xhx9pzhj 3830 9 shown show VBN cord-005646-xhx9pzhj 3830 10 to to TO cord-005646-xhx9pzhj 3830 11 produce produce VB cord-005646-xhx9pzhj 3830 12 this this DT cord-005646-xhx9pzhj 3830 13 desirable desirable JJ cord-005646-xhx9pzhj 3830 14 effect effect NN cord-005646-xhx9pzhj 3830 15 , , , cord-005646-xhx9pzhj 3830 16 but but CC cord-005646-xhx9pzhj 3830 17 is be VBZ cord-005646-xhx9pzhj 3830 18 relatively relatively RB cord-005646-xhx9pzhj 3830 19 difficult difficult JJ cord-005646-xhx9pzhj 3830 20 to to TO cord-005646-xhx9pzhj 3830 21 administer administer VB cord-005646-xhx9pzhj 3830 22 or or CC cord-005646-xhx9pzhj 3830 23 monitor monitor VB cord-005646-xhx9pzhj 3830 24 . . . cord-005646-xhx9pzhj 3831 1 We -PRON- PRP cord-005646-xhx9pzhj 3831 2 wondered wonder VBD cord-005646-xhx9pzhj 3831 3 whether whether IN cord-005646-xhx9pzhj 3831 4 NP NP NNP cord-005646-xhx9pzhj 3831 5 , , , cord-005646-xhx9pzhj 3831 6 chemicaIly chemicaIly NNS cord-005646-xhx9pzhj 3831 7 related relate VBN cord-005646-xhx9pzhj 3831 8 to to IN cord-005646-xhx9pzhj 3831 9 NO no RB cord-005646-xhx9pzhj 3831 10 but but CC cord-005646-xhx9pzhj 3831 11 more more RBR cord-005646-xhx9pzhj 3831 12 stable stable JJ cord-005646-xhx9pzhj 3831 13 in in IN cord-005646-xhx9pzhj 3831 14 solution solution NN cord-005646-xhx9pzhj 3831 15 , , , cord-005646-xhx9pzhj 3831 16 would would MD cord-005646-xhx9pzhj 3831 17 produce produce VB cord-005646-xhx9pzhj 3831 18 similar similar JJ cord-005646-xhx9pzhj 3831 19 physiologic physiologic JJ cord-005646-xhx9pzhj 3831 20 effects effect NNS cord-005646-xhx9pzhj 3831 21 when when WRB cord-005646-xhx9pzhj 3831 22 administered administer VBN cord-005646-xhx9pzhj 3831 23 in in IN cord-005646-xhx9pzhj 3831 24 the the DT cord-005646-xhx9pzhj 3831 25 convenient convenient JJ cord-005646-xhx9pzhj 3831 26 modality modality NN cord-005646-xhx9pzhj 3831 27 of of IN cord-005646-xhx9pzhj 3831 28 nebulization nebulization NN cord-005646-xhx9pzhj 3831 29 . . . cord-005646-xhx9pzhj 3832 1 Methods method NNS cord-005646-xhx9pzhj 3832 2 : : : cord-005646-xhx9pzhj 3832 3 9 9 CD cord-005646-xhx9pzhj 3832 4 piglets piglet NNS cord-005646-xhx9pzhj 3832 5 were be VBD cord-005646-xhx9pzhj 3832 6 anesthetized anesthetize VBN cord-005646-xhx9pzhj 3832 7 , , , cord-005646-xhx9pzhj 3832 8 mechanically mechanically RB cord-005646-xhx9pzhj 3832 9 ventilated ventilate VBN cord-005646-xhx9pzhj 3832 10 , , , cord-005646-xhx9pzhj 3832 11 and and CC cord-005646-xhx9pzhj 3832 12 surgically surgically RB cord-005646-xhx9pzhj 3832 13 instrumented instrument VBN cord-005646-xhx9pzhj 3832 14 . . . cord-005646-xhx9pzhj 3833 1 Systemic systemic JJ cord-005646-xhx9pzhj 3833 2 blood blood NN cord-005646-xhx9pzhj 3833 3 pressure pressure NN cord-005646-xhx9pzhj 3833 4 ( ( -LRB- cord-005646-xhx9pzhj 3833 5 BP BP NNP cord-005646-xhx9pzhj 3833 6 ) ) -RRB- cord-005646-xhx9pzhj 3833 7 , , , cord-005646-xhx9pzhj 3833 8 PAP pap NN cord-005646-xhx9pzhj 3833 9 , , , cord-005646-xhx9pzhj 3833 10 and and CC cord-005646-xhx9pzhj 3833 11 cardiac cardiac JJ cord-005646-xhx9pzhj 3833 12 output output NN cord-005646-xhx9pzhj 3833 13 ( ( -LRB- cord-005646-xhx9pzhj 3833 14 CO CO NNP cord-005646-xhx9pzhj 3833 15 ) ) -RRB- cord-005646-xhx9pzhj 3833 16 were be VBD cord-005646-xhx9pzhj 3833 17 monitored monitor VBN cord-005646-xhx9pzhj 3833 18 continuously continuously RB cord-005646-xhx9pzhj 3833 19 . . . cord-005646-xhx9pzhj 3834 1 After after IN cord-005646-xhx9pzhj 3834 2 postoperative postoperative JJ cord-005646-xhx9pzhj 3834 3 stabilization stabilization NN cord-005646-xhx9pzhj 3834 4 , , , cord-005646-xhx9pzhj 3834 5 0.9 0.9 CD cord-005646-xhx9pzhj 3834 6 % % NN cord-005646-xhx9pzhj 3834 7 NaC nac NN cord-005646-xhx9pzhj 3834 8 } } -RRB- cord-005646-xhx9pzhj 3834 9 nebulization nebulization NN cord-005646-xhx9pzhj 3834 10 was be VBD cord-005646-xhx9pzhj 3834 11 begun begin VBN cord-005646-xhx9pzhj 3834 12 , , , cord-005646-xhx9pzhj 3834 13 and and CC cord-005646-xhx9pzhj 3834 14 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3834 15 hypertensiorr hypertensiorr NNP cord-005646-xhx9pzhj 3834 16 was be VBD cord-005646-xhx9pzhj 3834 17 induced induce VBN cord-005646-xhx9pzhj 3834 18 by by IN cord-005646-xhx9pzhj 3834 19 reducing reduce VBG cord-005646-xhx9pzhj 3834 20 FiO2 FiO2 NNS cord-005646-xhx9pzhj 3834 21 from from IN cord-005646-xhx9pzhj 3834 22 0.30 0.30 CD cord-005646-xhx9pzhj 3834 23 to to IN cord-005646-xhx9pzhj 3834 24 0.07 0.07 CD cord-005646-xhx9pzhj 3834 25 . . . cord-005646-xhx9pzhj 3835 1 The the DT cord-005646-xhx9pzhj 3835 2 piglets piglet NNS cord-005646-xhx9pzhj 3835 3 were be VBD cord-005646-xhx9pzhj 3835 4 monitored monitor VBN cord-005646-xhx9pzhj 3835 5 for for IN cord-005646-xhx9pzhj 3835 6 15 15 CD cord-005646-xhx9pzhj 3835 7 minutes minute NNS cord-005646-xhx9pzhj 3835 8 during during IN cord-005646-xhx9pzhj 3835 9 this this DT cord-005646-xhx9pzhj 3835 10 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3835 11 phase phase NN cord-005646-xhx9pzhj 3835 12 , , , cord-005646-xhx9pzhj 3835 13 Next Next NNP cord-005646-xhx9pzhj 3835 14 , , , cord-005646-xhx9pzhj 3835 15 without without IN cord-005646-xhx9pzhj 3835 16 altering alter VBG cord-005646-xhx9pzhj 3835 17 FiO2 FiO2 NNS cord-005646-xhx9pzhj 3835 18 or or CC cord-005646-xhx9pzhj 3835 19 ventilator ventilator NN cord-005646-xhx9pzhj 3835 20 settings setting NNS cord-005646-xhx9pzhj 3835 21 , , , cord-005646-xhx9pzhj 3835 22 NP NP NNP cord-005646-xhx9pzhj 3835 23 ( ( -LRB- cord-005646-xhx9pzhj 3835 24 10 10 CD cord-005646-xhx9pzhj 3835 25 mg mg NNP cord-005646-xhx9pzhj 3835 26 / / SYM cord-005646-xhx9pzhj 3835 27 ml ml NNP cord-005646-xhx9pzhj 3835 28 , , , cord-005646-xhx9pzhj 3835 29 dissolved dissolve VBN cord-005646-xhx9pzhj 3835 30 in in IN cord-005646-xhx9pzhj 3835 31 0.9 0.9 CD cord-005646-xhx9pzhj 3835 32 % % NN cord-005646-xhx9pzhj 3835 33 NaCl nacl NN cord-005646-xhx9pzhj 3835 34 , , , cord-005646-xhx9pzhj 3835 35 flow flow NN cord-005646-xhx9pzhj 3835 36 4 4 CD cord-005646-xhx9pzhj 3835 37 Ipm Ipm NNP cord-005646-xhx9pzhj 3835 38 ) ) -RRB- cord-005646-xhx9pzhj 3835 39 was be VBD cord-005646-xhx9pzhj 3835 40 substitued substitue VBN cord-005646-xhx9pzhj 3835 41 for for IN cord-005646-xhx9pzhj 3835 42 0.9 0.9 CD cord-005646-xhx9pzhj 3835 43 % % NN cord-005646-xhx9pzhj 3835 44 NaCl nacl NN cord-005646-xhx9pzhj 3835 45 in in IN cord-005646-xhx9pzhj 3835 46 the the DT cord-005646-xhx9pzhj 3835 47 nebulizer nebulizer NN cord-005646-xhx9pzhj 3835 48 circuit circuit NN cord-005646-xhx9pzhj 3835 49 . . . cord-005646-xhx9pzhj 3836 1 NP NP NNP cord-005646-xhx9pzhj 3836 2 was be VBD cord-005646-xhx9pzhj 3836 3 nebulized nebulize VBN cord-005646-xhx9pzhj 3836 4 for for IN cord-005646-xhx9pzhj 3836 5 15 15 CD cord-005646-xhx9pzhj 3836 6 mins min NNS cord-005646-xhx9pzhj 3836 7 . . . cord-005646-xhx9pzhj 3837 1 Results result NNS cord-005646-xhx9pzhj 3837 2 : : : cord-005646-xhx9pzhj 3838 1 During during IN cord-005646-xhx9pzhj 3838 2 hypoxia hypoxia NN cord-005646-xhx9pzhj 3838 3 , , , cord-005646-xhx9pzhj 3838 4 PaO2 PaO2 NNS cord-005646-xhx9pzhj 3838 5 fell fall VBD cord-005646-xhx9pzhj 3838 6 from from IN cord-005646-xhx9pzhj 3838 7 159 159 CD cord-005646-xhx9pzhj 3838 8 to to TO cord-005646-xhx9pzhj 3838 9 29 29 CD cord-005646-xhx9pzhj 3838 10 mm mm CD cord-005646-xhx9pzhj 3838 11 Hg Hg NNS cord-005646-xhx9pzhj 3838 12 . . . cord-005646-xhx9pzhj 3839 1 PAP pap NN cord-005646-xhx9pzhj 3839 2 rose rise VBD cord-005646-xhx9pzhj 3839 3 during during IN cord-005646-xhx9pzhj 3839 4 hypoxia hypoxia NN cord-005646-xhx9pzhj 3839 5 from from IN cord-005646-xhx9pzhj 3839 6 14 14 CD cord-005646-xhx9pzhj 3839 7 to to TO cord-005646-xhx9pzhj 3839 8 31 31 CD cord-005646-xhx9pzhj 3839 9 torr torr NNS cord-005646-xhx9pzhj 3839 10 ( ( -LRB- cord-005646-xhx9pzhj 3839 11 p p NN cord-005646-xhx9pzhj 3839 12 < < XX cord-005646-xhx9pzhj 3839 13 0.01 0.01 CD cord-005646-xhx9pzhj 3839 14 ) ) -RRB- cord-005646-xhx9pzhj 3839 15 . . . cord-005646-xhx9pzhj 3840 1 , , , cord-005646-xhx9pzhj 3840 2 ^fhile ^fhile : cord-005646-xhx9pzhj 3840 3 BP BP NNP cord-005646-xhx9pzhj 3840 4 and and CC cord-005646-xhx9pzhj 3840 5 CO CO NNP cord-005646-xhx9pzhj 3840 6 did do VBD cord-005646-xhx9pzhj 3840 7 not not RB cord-005646-xhx9pzhj 3840 8 change change VB cord-005646-xhx9pzhj 3840 9 significantly significantly RB cord-005646-xhx9pzhj 3840 10 . . . cord-005646-xhx9pzhj 3841 1 PAP pap NN cord-005646-xhx9pzhj 3841 2 fell fall VBD cord-005646-xhx9pzhj 3841 3 during during IN cord-005646-xhx9pzhj 3841 4 nebulized nebulize VBN cord-005646-xhx9pzhj 3841 5 NP NP NNP cord-005646-xhx9pzhj 3841 6 in in IN cord-005646-xhx9pzhj 3841 7 each each DT cord-005646-xhx9pzhj 3841 8 piglet piglet NN cord-005646-xhx9pzhj 3841 9 , , , cord-005646-xhx9pzhj 3841 10 ( ( -LRB- cord-005646-xhx9pzhj 3841 11 mean mean VB cord-005646-xhx9pzhj 3841 12 APAP APAP NNP cord-005646-xhx9pzhj 3841 13 = = SYM cord-005646-xhx9pzhj 3841 14 31 31 CD cord-005646-xhx9pzhj 3841 15 to to TO cord-005646-xhx9pzhj 3841 16 21 21 CD cord-005646-xhx9pzhj 3841 17 torr torr NNS cord-005646-xhx9pzhj 3841 18 ; ; : cord-005646-xhx9pzhj 3841 19 p p NN cord-005646-xhx9pzhj 3841 20 < < XX cord-005646-xhx9pzhj 3841 21 0.01 0.01 CD cord-005646-xhx9pzhj 3841 22 ; ; : cord-005646-xhx9pzhj 3841 23 mean mean JJ cord-005646-xhx9pzhj 3841 24 reduction reduction NN cord-005646-xhx9pzhj 3841 25 of of IN cord-005646-xhx9pzhj 3841 26 hypoxia hypoxia NN cord-005646-xhx9pzhj 3841 27 - - HYPH cord-005646-xhx9pzhj 3841 28 induced induce VBN cord-005646-xhx9pzhj 3841 29 rise rise NN cord-005646-xhx9pzhj 3841 30 in in IN cord-005646-xhx9pzhj 3841 31 PAP pap NN cord-005646-xhx9pzhj 3841 32 = = SYM cord-005646-xhx9pzhj 3841 33 61 61 CD cord-005646-xhx9pzhj 3841 34 % % NN cord-005646-xhx9pzhj 3841 35 ; ; : cord-005646-xhx9pzhj 3841 36 range range NN cord-005646-xhx9pzhj 3841 37 : : : cord-005646-xhx9pzhj 3841 38 36 36 CD cord-005646-xhx9pzhj 3841 39 to to TO cord-005646-xhx9pzhj 3841 40 78 78 CD cord-005646-xhx9pzhj 3841 41 % % NN cord-005646-xhx9pzhj 3841 42 ; ; : cord-005646-xhx9pzhj 3841 43 p p NN cord-005646-xhx9pzhj 3841 44 < < XX cord-005646-xhx9pzhj 3841 45 0.01 0.01 CD cord-005646-xhx9pzhj 3841 46 ) ) -RRB- cord-005646-xhx9pzhj 3841 47 . . . cord-005646-xhx9pzhj 3842 1 PVR PVR NNP cord-005646-xhx9pzhj 3842 2 / / SYM cord-005646-xhx9pzhj 3842 3 SVR SVR NNP cord-005646-xhx9pzhj 3842 4 fell fall VBD cord-005646-xhx9pzhj 3842 5 by by IN cord-005646-xhx9pzhj 3842 6 28 28 CD cord-005646-xhx9pzhj 3842 7 % % NN cord-005646-xhx9pzhj 3842 8 during during IN cord-005646-xhx9pzhj 3842 9 NP NP NNP cord-005646-xhx9pzhj 3842 10 nebulization nebulization NN cord-005646-xhx9pzhj 3843 1 ( ( -LRB- cord-005646-xhx9pzhj 3843 2 p p NN cord-005646-xhx9pzhj 3843 3 < < XX cord-005646-xhx9pzhj 3843 4 0.01 0.01 CD cord-005646-xhx9pzhj 3843 5 ) ) -RRB- cord-005646-xhx9pzhj 3843 6 , , , cord-005646-xhx9pzhj 3843 7 while while IN cord-005646-xhx9pzhj 3843 8 BP BP NNP cord-005646-xhx9pzhj 3843 9 and and CC cord-005646-xhx9pzhj 3843 10 CO CO NNP cord-005646-xhx9pzhj 3843 11 did do VBD cord-005646-xhx9pzhj 3843 12 not not RB cord-005646-xhx9pzhj 3843 13 fall fall VB cord-005646-xhx9pzhj 3843 14 significantly significantly RB cord-005646-xhx9pzhj 3843 15 ( ( -LRB- cord-005646-xhx9pzhj 3843 16 90 90 CD cord-005646-xhx9pzhj 3843 17 to to TO cord-005646-xhx9pzhj 3843 18 86 86 CD cord-005646-xhx9pzhj 3843 19 tort tort NN cord-005646-xhx9pzhj 3843 20 ; ; : cord-005646-xhx9pzhj 3843 21 653 653 CD cord-005646-xhx9pzhj 3843 22 to to IN cord-005646-xhx9pzhj 3843 23 636 636 CD cord-005646-xhx9pzhj 3843 24 mLlkg mLlkg NNP cord-005646-xhx9pzhj 3843 25 - - HYPH cord-005646-xhx9pzhj 3843 26 min min NNP cord-005646-xhx9pzhj 3843 27 ) ) -RRB- cord-005646-xhx9pzhj 3843 28 , , , cord-005646-xhx9pzhj 3843 29 The the DT cord-005646-xhx9pzhj 3843 30 reduction reduction NN cord-005646-xhx9pzhj 3843 31 in in IN cord-005646-xhx9pzhj 3843 32 PAP pap NN cord-005646-xhx9pzhj 3843 33 began begin VBD cord-005646-xhx9pzhj 3843 34 within within IN cord-005646-xhx9pzhj 3843 35 2 2 CD cord-005646-xhx9pzhj 3843 36 minutes minute NNS cord-005646-xhx9pzhj 3843 37 of of IN cord-005646-xhx9pzhj 3843 38 the the DT cord-005646-xhx9pzhj 3843 39 onset onset NN cord-005646-xhx9pzhj 3843 40 of of IN cord-005646-xhx9pzhj 3843 41 nebulized nebulize VBN cord-005646-xhx9pzhj 3843 42 NP NP NNP cord-005646-xhx9pzhj 3843 43 , , , cord-005646-xhx9pzhj 3843 44 and and CC cord-005646-xhx9pzhj 3843 45 appeared appear VBD cord-005646-xhx9pzhj 3843 46 to to TO cord-005646-xhx9pzhj 3843 47 reach reach VB cord-005646-xhx9pzhj 3843 48 a a DT cord-005646-xhx9pzhj 3843 49 plateau plateau NN cord-005646-xhx9pzhj 3843 50 by by IN cord-005646-xhx9pzhj 3843 51 15 15 CD cord-005646-xhx9pzhj 3843 52 minutes minute NNS cord-005646-xhx9pzhj 3843 53 . . . cord-005646-xhx9pzhj 3844 1 No no DT cord-005646-xhx9pzhj 3844 2 tachyphylaxis tachyphylaxis NNP cord-005646-xhx9pzhj 3844 3 to to IN cord-005646-xhx9pzhj 3844 4 nebulized nebulize VBN cord-005646-xhx9pzhj 3844 5 NP NP NNP cord-005646-xhx9pzhj 3844 6 was be VBD cord-005646-xhx9pzhj 3844 7 noted note VBN cord-005646-xhx9pzhj 3844 8 . . . cord-005646-xhx9pzhj 3845 1 Nebulized Nebulized NNP cord-005646-xhx9pzhj 3845 2 NP NP NNP cord-005646-xhx9pzhj 3845 3 did do VBD cord-005646-xhx9pzhj 3845 4 not not RB cord-005646-xhx9pzhj 3845 5 significantly significantly RB cord-005646-xhx9pzhj 3845 6 affect affect VB cord-005646-xhx9pzhj 3845 7 PAP pap NN cord-005646-xhx9pzhj 3845 8 , , , cord-005646-xhx9pzhj 3845 9 BP BP NNP cord-005646-xhx9pzhj 3845 10 , , , cord-005646-xhx9pzhj 3845 11 or or CC cord-005646-xhx9pzhj 3845 12 CO CO NNP cord-005646-xhx9pzhj 3845 13 under under IN cord-005646-xhx9pzhj 3845 14 normoxic normoxic JJ cord-005646-xhx9pzhj 3845 15 conditions condition NNS cord-005646-xhx9pzhj 3845 16 . . . cord-005646-xhx9pzhj 3846 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3846 2 : : : cord-005646-xhx9pzhj 3847 1 1 1 LS cord-005646-xhx9pzhj 3847 2 ) ) -RRB- cord-005646-xhx9pzhj 3847 3 Like like UH cord-005646-xhx9pzhj 3847 4 NO no UH cord-005646-xhx9pzhj 3847 5 , , , cord-005646-xhx9pzhj 3847 6 NP NP NNP cord-005646-xhx9pzhj 3847 7 selectively selectively RB cord-005646-xhx9pzhj 3847 8 reduced reduce VBN cord-005646-xhx9pzhj 3847 9 hypoxia hypoxia NN cord-005646-xhx9pzhj 3847 10 - - HYPH cord-005646-xhx9pzhj 3847 11 induced induce VBN cord-005646-xhx9pzhj 3847 12 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3847 13 hypertension hypertension NN cord-005646-xhx9pzhj 3847 14 without without IN cord-005646-xhx9pzhj 3847 15 altering alter VBG cord-005646-xhx9pzhj 3847 16 systemic systemic JJ cord-005646-xhx9pzhj 3847 17 BP BP NNP cord-005646-xhx9pzhj 3847 18 , , , cord-005646-xhx9pzhj 3847 19 2 2 CD cord-005646-xhx9pzhj 3847 20 ) ) -RRB- cord-005646-xhx9pzhj 3848 1 Unlike unlike IN cord-005646-xhx9pzhj 3848 2 NO no RB cord-005646-xhx9pzhj 3848 3 , , , cord-005646-xhx9pzhj 3848 4 NP NP NNP cord-005646-xhx9pzhj 3848 5 can can MD cord-005646-xhx9pzhj 3848 6 be be VB cord-005646-xhx9pzhj 3848 7 administered administer VBN cord-005646-xhx9pzhj 3848 8 by by IN cord-005646-xhx9pzhj 3848 9 nebulizer nebulizer NN cord-005646-xhx9pzhj 3848 10 , , , cord-005646-xhx9pzhj 3848 11 a a DT cord-005646-xhx9pzhj 3848 12 technique technique NN cord-005646-xhx9pzhj 3848 13 familiar familiar JJ cord-005646-xhx9pzhj 3848 14 to to IN cord-005646-xhx9pzhj 3848 15 virtually virtually RB cord-005646-xhx9pzhj 3848 16 all all DT cord-005646-xhx9pzhj 3848 17 health health NN cord-005646-xhx9pzhj 3848 18 - - HYPH cord-005646-xhx9pzhj 3848 19 care care NN cord-005646-xhx9pzhj 3848 20 providers provider NNS cord-005646-xhx9pzhj 3848 21 , , , cord-005646-xhx9pzhj 3848 22 and and CC cord-005646-xhx9pzhj 3848 23 potentially potentially RB cord-005646-xhx9pzhj 3848 24 adaptable adaptable JJ cord-005646-xhx9pzhj 3848 25 to to IN cord-005646-xhx9pzhj 3848 26 both both CC cord-005646-xhx9pzhj 3848 27 intubated intubate VBN cord-005646-xhx9pzhj 3848 28 and and CC cord-005646-xhx9pzhj 3848 29 non non JJ cord-005646-xhx9pzhj 3848 30 - - JJ cord-005646-xhx9pzhj 3848 31 intubated intubate VBN cord-005646-xhx9pzhj 3848 32 patients patient NNS cord-005646-xhx9pzhj 3848 33 . . . cord-005646-xhx9pzhj 3849 1 3 3 LS cord-005646-xhx9pzhj 3849 2 } } -RRB- cord-005646-xhx9pzhj 3850 1 Nebulized Nebulized NNP cord-005646-xhx9pzhj 3850 2 NP NP NNP cord-005646-xhx9pzhj 3850 3 may may MD cord-005646-xhx9pzhj 3850 4 be be VB cord-005646-xhx9pzhj 3850 5 beneficial beneficial JJ cord-005646-xhx9pzhj 3850 6 in in IN cord-005646-xhx9pzhj 3850 7 clinical clinical JJ cord-005646-xhx9pzhj 3850 8 contexts context NNS cord-005646-xhx9pzhj 3850 9 where where WRB cord-005646-xhx9pzhj 3850 10 inhaled inhale VBN cord-005646-xhx9pzhj 3850 11 NO no DT cord-005646-xhx9pzhj 3850 12 is be VBZ cord-005646-xhx9pzhj 3850 13 impractical impractical JJ cord-005646-xhx9pzhj 3850 14 . . . cord-005646-xhx9pzhj 3851 1 Dang Dang NNP cord-005646-xhx9pzhj 3851 2 Phuong Phuong NNP cord-005646-xhx9pzhj 3851 3 Kiet Kiet NNP cord-005646-xhx9pzhj 3851 4 and and CC cord-005646-xhx9pzhj 3851 5 Nguyen Nguyen NNP cord-005646-xhx9pzhj 3851 6 Xuan Xuan NNP cord-005646-xhx9pzhj 3851 7 Thu Thu NNP cord-005646-xhx9pzhj 3851 8 Examining examine VBG cord-005646-xhx9pzhj 3851 9 6 6 CD cord-005646-xhx9pzhj 3851 10 cases case NNS cord-005646-xhx9pzhj 3851 11 of of IN cord-005646-xhx9pzhj 3851 12 purulent purulent JJ cord-005646-xhx9pzhj 3851 13 pericarditis pericarditis NN cord-005646-xhx9pzhj 3851 14 with with IN cord-005646-xhx9pzhj 3851 15 various various JJ cord-005646-xhx9pzhj 3851 16 clinical clinical JJ cord-005646-xhx9pzhj 3851 17 forms form NNS cord-005646-xhx9pzhj 3851 18 treated treat VBN cord-005646-xhx9pzhj 3851 19 by by IN cord-005646-xhx9pzhj 3851 20 surgery surgery NN cord-005646-xhx9pzhj 3851 21 , , , cord-005646-xhx9pzhj 3851 22 the the DT cord-005646-xhx9pzhj 3851 23 authors author NNS cord-005646-xhx9pzhj 3851 24 drew draw VBD cord-005646-xhx9pzhj 3851 25 the the DT cord-005646-xhx9pzhj 3851 26 following follow VBG cord-005646-xhx9pzhj 3851 27 experiences experience NNS cord-005646-xhx9pzhj 3851 28 for for IN cord-005646-xhx9pzhj 3851 29 their -PRON- PRP$ cord-005646-xhx9pzhj 3851 30 diagnosis diagnosis NN cord-005646-xhx9pzhj 3851 31 . . . cord-005646-xhx9pzhj 3852 1 t. t. NNP cord-005646-xhx9pzhj 3852 2 Clinical clinical JJ cord-005646-xhx9pzhj 3852 3 factors factor NNS cord-005646-xhx9pzhj 3852 4 . . . cord-005646-xhx9pzhj 3853 1 Purulent purulent JJ cord-005646-xhx9pzhj 3853 2 pericarditis pericarditis NN cord-005646-xhx9pzhj 3853 3 appeared appear VBD cord-005646-xhx9pzhj 3853 4 like like IN cord-005646-xhx9pzhj 3853 5 a a DT cord-005646-xhx9pzhj 3853 6 cardiac cardiac JJ cord-005646-xhx9pzhj 3853 7 tamponade tamponade NN cord-005646-xhx9pzhj 3853 8 in in IN cord-005646-xhx9pzhj 3853 9 a a DT cord-005646-xhx9pzhj 3853 10 septicemia septicemia NN cord-005646-xhx9pzhj 3853 11 due due IN cord-005646-xhx9pzhj 3853 12 to to IN cord-005646-xhx9pzhj 3853 13 staphylococci staphylococcus NNS cord-005646-xhx9pzhj 3853 14 with with IN cord-005646-xhx9pzhj 3853 15 dassieal dassieal NN cord-005646-xhx9pzhj 3853 16 symptoms symptom NNS cord-005646-xhx9pzhj 3853 17 : : : cord-005646-xhx9pzhj 3853 18 severe severe JJ cord-005646-xhx9pzhj 3853 19 dyspnea dyspnea NN cord-005646-xhx9pzhj 3853 20 , , , cord-005646-xhx9pzhj 3853 21 tachycardia tachycardia NN cord-005646-xhx9pzhj 3853 22 , , , cord-005646-xhx9pzhj 3853 23 faint faint JJ cord-005646-xhx9pzhj 3853 24 heartsound heartsound NNP cord-005646-xhx9pzhj 3853 25 , , , cord-005646-xhx9pzhj 3853 26 big big JJ cord-005646-xhx9pzhj 3853 27 liver liver NN cord-005646-xhx9pzhj 3853 28 , , , cord-005646-xhx9pzhj 3853 29 prominent prominent JJ cord-005646-xhx9pzhj 3853 30 cervical cervical JJ cord-005646-xhx9pzhj 3853 31 vein vein NN cord-005646-xhx9pzhj 3853 32 ; ; : cord-005646-xhx9pzhj 3853 33 rentgenography rentgenography NN cord-005646-xhx9pzhj 3853 34 of of IN cord-005646-xhx9pzhj 3853 35 the the DT cord-005646-xhx9pzhj 3853 36 chest chest NN cord-005646-xhx9pzhj 3853 37 showing show VBG cord-005646-xhx9pzhj 3853 38 enlargement enlargement NN cord-005646-xhx9pzhj 3853 39 of of IN cord-005646-xhx9pzhj 3853 40 the the DT cord-005646-xhx9pzhj 3853 41 cardiac cardiac JJ cord-005646-xhx9pzhj 3853 42 silhouette silhouette NN cord-005646-xhx9pzhj 3853 43 , , , cord-005646-xhx9pzhj 3853 44 a a DT cord-005646-xhx9pzhj 3853 45 diminution diminution NN cord-005646-xhx9pzhj 3853 46 of of IN cord-005646-xhx9pzhj 3853 47 ventricular ventricular JJ cord-005646-xhx9pzhj 3853 48 pulsations pulsation NNS cord-005646-xhx9pzhj 3853 49 , , , cord-005646-xhx9pzhj 3854 1 ~i ~i NNP cord-005646-xhx9pzhj 3854 2 clear clear JJ cord-005646-xhx9pzhj 3854 3 lung lung NN cord-005646-xhx9pzhj 3854 4 field field NN cord-005646-xhx9pzhj 3854 5 . . . cord-005646-xhx9pzhj 3855 1 By by IN cord-005646-xhx9pzhj 3855 2 an an DT cord-005646-xhx9pzhj 3855 3 emergency emergency NN cord-005646-xhx9pzhj 3855 4 operation operation NN cord-005646-xhx9pzhj 3855 5 , , , cord-005646-xhx9pzhj 3855 6 500ml 500ml RB cord-005646-xhx9pzhj 3855 7 of of IN cord-005646-xhx9pzhj 3855 8 diluted diluted JJ cord-005646-xhx9pzhj 3855 9 blood blood NN cord-005646-xhx9pzhj 3855 10 were be VBD cord-005646-xhx9pzhj 3855 11 drained drain VBN cord-005646-xhx9pzhj 3855 12 . . . cord-005646-xhx9pzhj 3856 1 Purulent purulent JJ cord-005646-xhx9pzhj 3856 2 pericarditis pericarditis NN cord-005646-xhx9pzhj 3856 3 and and CC cord-005646-xhx9pzhj 3856 4 pleural pleural JJ cord-005646-xhx9pzhj 3856 5 effusion effusion NN cord-005646-xhx9pzhj 3856 6 appeared appear VBD cord-005646-xhx9pzhj 3856 7 at at IN cord-005646-xhx9pzhj 3856 8 the the DT cord-005646-xhx9pzhj 3856 9 same same JJ cord-005646-xhx9pzhj 3856 10 time time NN cord-005646-xhx9pzhj 3856 11 but but CC cord-005646-xhx9pzhj 3856 12 at at IN cord-005646-xhx9pzhj 3856 13 first first JJ cord-005646-xhx9pzhj 3856 14 tile tile NN cord-005646-xhx9pzhj 3856 15 symptoms symptom NNS cord-005646-xhx9pzhj 3856 16 of of IN cord-005646-xhx9pzhj 3856 17 purulent purulent JJ cord-005646-xhx9pzhj 3856 18 pericarditis pericarditis NN cord-005646-xhx9pzhj 3856 19 were be VBD cord-005646-xhx9pzhj 3856 20 masked mask VBN cord-005646-xhx9pzhj 3856 21 by by IN cord-005646-xhx9pzhj 3856 22 the the DT cord-005646-xhx9pzhj 3856 23 predominant predominant JJ cord-005646-xhx9pzhj 3856 24 symptoms symptom NNS cord-005646-xhx9pzhj 3856 25 of of IN cord-005646-xhx9pzhj 3856 26 plearal plearal JJ cord-005646-xhx9pzhj 3856 27 efihsion efihsion NN cord-005646-xhx9pzhj 3856 28 . . . cord-005646-xhx9pzhj 3857 1 After after IN cord-005646-xhx9pzhj 3857 2 the the DT cord-005646-xhx9pzhj 3857 3 pleura pleura NN cord-005646-xhx9pzhj 3857 4 was be VBD cord-005646-xhx9pzhj 3857 5 drained drain VBN cord-005646-xhx9pzhj 3857 6 , , , cord-005646-xhx9pzhj 3857 7 its -PRON- PRP$ cord-005646-xhx9pzhj 3857 8 pus pus NN cord-005646-xhx9pzhj 3857 9 was be VBD cord-005646-xhx9pzhj 3857 10 no no RB cord-005646-xhx9pzhj 3857 11 more more JJR cord-005646-xhx9pzhj 3857 12 , , , cord-005646-xhx9pzhj 3857 13 the the DT cord-005646-xhx9pzhj 3857 14 general general JJ cord-005646-xhx9pzhj 3857 15 state state NN cord-005646-xhx9pzhj 3857 16 was be VBD cord-005646-xhx9pzhj 3857 17 relatively relatively RB cord-005646-xhx9pzhj 3857 18 stabilized stabilize VBN cord-005646-xhx9pzhj 3857 19 but but CC cord-005646-xhx9pzhj 3857 20 there there EX cord-005646-xhx9pzhj 3857 21 still still RB cord-005646-xhx9pzhj 3857 22 were be VBD cord-005646-xhx9pzhj 3857 23 big big JJ cord-005646-xhx9pzhj 3857 24 liver liver NN cord-005646-xhx9pzhj 3857 25 , , , cord-005646-xhx9pzhj 3857 26 dyspnea dyspnea NN cord-005646-xhx9pzhj 3857 27 , , , cord-005646-xhx9pzhj 3857 28 enlargement enlargement NN cord-005646-xhx9pzhj 3857 29 of of IN cord-005646-xhx9pzhj 3857 30 the the DT cord-005646-xhx9pzhj 3857 31 cardiac cardiac JJ cord-005646-xhx9pzhj 3857 32 silhouette silhouette NN cord-005646-xhx9pzhj 3857 33 while while IN cord-005646-xhx9pzhj 3857 34 central central JJ cord-005646-xhx9pzhj 3857 35 venous venous JJ cord-005646-xhx9pzhj 3857 36 pressure pressure NN cord-005646-xhx9pzhj 3857 37 increased increase VBD cord-005646-xhx9pzhj 3857 38 . . . cord-005646-xhx9pzhj 3858 1 Purulent purulent JJ cord-005646-xhx9pzhj 3858 2 pericarditis pericarditis NN cord-005646-xhx9pzhj 3858 3 appeared appear VBD cord-005646-xhx9pzhj 3858 4 late late RB cord-005646-xhx9pzhj 3858 5 . . . cord-005646-xhx9pzhj 3859 1 In in IN cord-005646-xhx9pzhj 3859 2 the the DT cord-005646-xhx9pzhj 3859 3 first first JJ cord-005646-xhx9pzhj 3859 4 stage stage NN cord-005646-xhx9pzhj 3859 5 ( ( -LRB- cord-005646-xhx9pzhj 3859 6 about about RB cord-005646-xhx9pzhj 3859 7 2 2 CD cord-005646-xhx9pzhj 3859 8 weeks week NNS cord-005646-xhx9pzhj 3859 9 ) ) -RRB- cord-005646-xhx9pzhj 3859 10 there there EX cord-005646-xhx9pzhj 3859 11 was be VBD cord-005646-xhx9pzhj 3859 12 no no DT cord-005646-xhx9pzhj 3859 13 suspected suspect VBN cord-005646-xhx9pzhj 3859 14 sign sign NN cord-005646-xhx9pzhj 3859 15 . . . cord-005646-xhx9pzhj 3860 1 Later later RB cord-005646-xhx9pzhj 3860 2 on on RB cord-005646-xhx9pzhj 3860 3 gradually gradually RB cord-005646-xhx9pzhj 3860 4 appeared appear VBD cord-005646-xhx9pzhj 3860 5 such such JJ cord-005646-xhx9pzhj 3860 6 symptoms symptom NNS cord-005646-xhx9pzhj 3860 7 as as IN cord-005646-xhx9pzhj 3860 8 dyspnea dyspnea NN cord-005646-xhx9pzhj 3860 9 ( ( -LRB- cord-005646-xhx9pzhj 3860 10 during during IN cord-005646-xhx9pzhj 3860 11 serum serum NN cord-005646-xhx9pzhj 3860 12 transfusion transfusion NN cord-005646-xhx9pzhj 3860 13 for for IN cord-005646-xhx9pzhj 3860 14 instance instance NN cord-005646-xhx9pzhj 3860 15 ) ) -RRB- cord-005646-xhx9pzhj 3860 16 . . . cord-005646-xhx9pzhj 3861 1 Central central JJ cord-005646-xhx9pzhj 3861 2 veinous veinous JJ cord-005646-xhx9pzhj 3861 3 pressure pressure NN cord-005646-xhx9pzhj 3861 4 also also RB cord-005646-xhx9pzhj 3861 5 raised raise VBD cord-005646-xhx9pzhj 3861 6 . . . cord-005646-xhx9pzhj 3862 1 The the DT cord-005646-xhx9pzhj 3862 2 heart heart NN cord-005646-xhx9pzhj 3862 3 chest chest NN cord-005646-xhx9pzhj 3862 4 diametre diametre NN cord-005646-xhx9pzhj 3862 5 increased increase VBD cord-005646-xhx9pzhj 3862 6 at at IN cord-005646-xhx9pzhj 3862 7 first first RB cord-005646-xhx9pzhj 3862 8 ( ( -LRB- cord-005646-xhx9pzhj 3862 9 up up IN cord-005646-xhx9pzhj 3862 10 to to TO cord-005646-xhx9pzhj 3862 11 60 60 CD cord-005646-xhx9pzhj 3862 12 - - SYM cord-005646-xhx9pzhj 3862 13 65 65 CD cord-005646-xhx9pzhj 3862 14 % % NN cord-005646-xhx9pzhj 3862 15 ) ) -RRB- cord-005646-xhx9pzhj 3862 16 then then RB cord-005646-xhx9pzhj 3862 17 decreased decrease VBD cord-005646-xhx9pzhj 3862 18 ( ( -LRB- cord-005646-xhx9pzhj 3862 19 down down IN cord-005646-xhx9pzhj 3862 20 to to IN cord-005646-xhx9pzhj 3862 21 below below IN cord-005646-xhx9pzhj 3862 22 50 50 CD cord-005646-xhx9pzhj 3862 23 % % NN cord-005646-xhx9pzhj 3862 24 ) ) -RRB- cord-005646-xhx9pzhj 3862 25 but but CC cord-005646-xhx9pzhj 3862 26 the the DT cord-005646-xhx9pzhj 3862 27 liver liver NN cord-005646-xhx9pzhj 3862 28 kept keep VBD cord-005646-xhx9pzhj 3862 29 on on IN cord-005646-xhx9pzhj 3862 30 swelling swell VBG cord-005646-xhx9pzhj 3862 31 together together RB cord-005646-xhx9pzhj 3862 32 with with IN cord-005646-xhx9pzhj 3862 33 the the DT cord-005646-xhx9pzhj 3862 34 particular particular JJ cord-005646-xhx9pzhj 3862 35 changes change NNS cord-005646-xhx9pzhj 3862 36 of of IN cord-005646-xhx9pzhj 3862 37 electroeaediegramme electroeaediegramme NN cord-005646-xhx9pzhj 3862 38 . . . cord-005646-xhx9pzhj 3863 1 Now now RB cord-005646-xhx9pzhj 3863 2 the the DT cord-005646-xhx9pzhj 3863 3 pericardium pericardium NN cord-005646-xhx9pzhj 3863 4 had have VBD cord-005646-xhx9pzhj 3863 5 no no DT cord-005646-xhx9pzhj 3863 6 more more JJR cord-005646-xhx9pzhj 3863 7 pus pus NN cord-005646-xhx9pzhj 3863 8 but but CC cord-005646-xhx9pzhj 3863 9 get get VB cord-005646-xhx9pzhj 3863 10 fibrous fibrous JJ cord-005646-xhx9pzhj 3863 11 ( ( -LRB- cord-005646-xhx9pzhj 3863 12 up up IN cord-005646-xhx9pzhj 3863 13 to to IN cord-005646-xhx9pzhj 3863 14 3ram 3ram CD cord-005646-xhx9pzhj 3863 15 ) ) -RRB- cord-005646-xhx9pzhj 3863 16 thus thus RB cord-005646-xhx9pzhj 3863 17 constricting constrict VBG cord-005646-xhx9pzhj 3863 18 the the DT cord-005646-xhx9pzhj 3863 19 heart heart NN cord-005646-xhx9pzhj 3863 20 and and CC cord-005646-xhx9pzhj 3863 21 its -PRON- PRP$ cord-005646-xhx9pzhj 3863 22 main main JJ cord-005646-xhx9pzhj 3863 23 arteries artery NNS cord-005646-xhx9pzhj 3863 24 0ike 0ike CD cord-005646-xhx9pzhj 3863 25 Pick Pick NNP cord-005646-xhx9pzhj 3863 26 syndrome syndrome NN cord-005646-xhx9pzhj 3863 27 ) ) -RRB- cord-005646-xhx9pzhj 3863 28 . . . cord-005646-xhx9pzhj 3864 1 2 2 LS cord-005646-xhx9pzhj 3864 2 . . . cord-005646-xhx9pzhj 3865 1 Diagnostic diagnostic JJ cord-005646-xhx9pzhj 3865 2 values value NNS cord-005646-xhx9pzhj 3865 3 of of IN cord-005646-xhx9pzhj 3865 4 electrocardiograms electrocardiogram NNS cord-005646-xhx9pzhj 3865 5 : : : cord-005646-xhx9pzhj 3865 6 Common common JJ cord-005646-xhx9pzhj 3865 7 signs sign NNS cord-005646-xhx9pzhj 3865 8 of of IN cord-005646-xhx9pzhj 3865 9 ECG ECG NNP cord-005646-xhx9pzhj 3865 10 related relate VBN cord-005646-xhx9pzhj 3865 11 of of IN cord-005646-xhx9pzhj 3865 12 these these DT cord-005646-xhx9pzhj 3865 13 purulent purulent JJ cord-005646-xhx9pzhj 3865 14 pericarditis pericarditis NN cord-005646-xhx9pzhj 3865 15 were be VBD cord-005646-xhx9pzhj 3865 16 : : : cord-005646-xhx9pzhj 3865 17 a a DT cord-005646-xhx9pzhj 3865 18 diminution diminution NN cord-005646-xhx9pzhj 3865 19 of of IN cord-005646-xhx9pzhj 3865 20 voltage voltage NN cord-005646-xhx9pzhj 3865 21 , , , cord-005646-xhx9pzhj 3865 22 a a DT cord-005646-xhx9pzhj 3865 23 widespread widespread JJ cord-005646-xhx9pzhj 3865 24 elevation elevation NN cord-005646-xhx9pzhj 3865 25 of of IN cord-005646-xhx9pzhj 3865 26 the the DT cord-005646-xhx9pzhj 3865 27 ST ST NNP cord-005646-xhx9pzhj 3865 28 segment segment NN cord-005646-xhx9pzhj 3865 29 , , , cord-005646-xhx9pzhj 3865 30 the the DT cord-005646-xhx9pzhj 3865 31 TF TF NNP cord-005646-xhx9pzhj 3865 32 wave wave NN cord-005646-xhx9pzhj 3865 33 flattened flatten VBN cord-005646-xhx9pzhj 3865 34 and and CC cord-005646-xhx9pzhj 3865 35 inverted invert VBN cord-005646-xhx9pzhj 3865 36 . . . cord-005646-xhx9pzhj 3866 1 However however RB cord-005646-xhx9pzhj 3866 2 , , , cord-005646-xhx9pzhj 3866 3 what what WP cord-005646-xhx9pzhj 3866 4 should should MD cord-005646-xhx9pzhj 3866 5 be be VB cord-005646-xhx9pzhj 3866 6 stressed stress VBN cord-005646-xhx9pzhj 3866 7 was be VBD cord-005646-xhx9pzhj 3866 8 : : : cord-005646-xhx9pzhj 3866 9 the the DT cord-005646-xhx9pzhj 3866 10 diagnostic diagnostic JJ cord-005646-xhx9pzhj 3866 11 values value NNS cord-005646-xhx9pzhj 3866 12 of of IN cord-005646-xhx9pzhj 3866 13 an an DT cord-005646-xhx9pzhj 3866 14 electrocardiogram electrocardiogram NN cord-005646-xhx9pzhj 3866 15 for for IN cord-005646-xhx9pzhj 3866 16 purulent purulent JJ cord-005646-xhx9pzhj 3866 17 pericarditis pericarditis NN cord-005646-xhx9pzhj 3866 18 was be VBD cord-005646-xhx9pzhj 3866 19 mainly mainly RB cord-005646-xhx9pzhj 3866 20 in in IN cord-005646-xhx9pzhj 3866 21 the the DT cord-005646-xhx9pzhj 3866 22 dynamics dynamic NNS cord-005646-xhx9pzhj 3866 23 of of IN cord-005646-xhx9pzhj 3866 24 their -PRON- PRP$ cord-005646-xhx9pzhj 3866 25 signs sign NNS cord-005646-xhx9pzhj 3866 26 : : : cord-005646-xhx9pzhj 3867 1 in in IN cord-005646-xhx9pzhj 3867 2 the the DT cord-005646-xhx9pzhj 3867 3 first first JJ cord-005646-xhx9pzhj 3867 4 week week NN cord-005646-xhx9pzhj 3867 5 , , , cord-005646-xhx9pzhj 3867 6 the the DT cord-005646-xhx9pzhj 3867 7 voltage voltage NN cord-005646-xhx9pzhj 3867 8 diminished diminish VBD cord-005646-xhx9pzhj 3867 9 corresponding correspond VBG cord-005646-xhx9pzhj 3867 10 to to IN cord-005646-xhx9pzhj 3867 11 a a DT cord-005646-xhx9pzhj 3867 12 pericardium pericardium NN cord-005646-xhx9pzhj 3867 13 containing contain VBG cord-005646-xhx9pzhj 3867 14 pus pus NN cord-005646-xhx9pzhj 3867 15 , , , cord-005646-xhx9pzhj 3867 16 while while IN cord-005646-xhx9pzhj 3867 17 the the DT cord-005646-xhx9pzhj 3867 18 ST ST NNP cord-005646-xhx9pzhj 3867 19 segment segment NN cord-005646-xhx9pzhj 3867 20 went go VBD cord-005646-xhx9pzhj 3867 21 up up RP cord-005646-xhx9pzhj 3867 22 then then RB cord-005646-xhx9pzhj 3867 23 seemed seem VBD cord-005646-xhx9pzhj 3867 24 parallel parallel JJ cord-005646-xhx9pzhj 3867 25 to to IN cord-005646-xhx9pzhj 3867 26 the the DT cord-005646-xhx9pzhj 3867 27 fibrosis fibrosis NN cord-005646-xhx9pzhj 3867 28 of of IN cord-005646-xhx9pzhj 3867 29 the the DT cord-005646-xhx9pzhj 3867 30 epicardium epicardium NN cord-005646-xhx9pzhj 3867 31 , , , cord-005646-xhx9pzhj 3867 32 the the DT cord-005646-xhx9pzhj 3867 33 liver liver NN cord-005646-xhx9pzhj 3867 34 swelled swell VBD cord-005646-xhx9pzhj 3867 35 , , , cord-005646-xhx9pzhj 3867 36 the the DT cord-005646-xhx9pzhj 3867 37 central central JJ cord-005646-xhx9pzhj 3867 38 velnous velnous JJ cord-005646-xhx9pzhj 3867 39 pressure pressure NN cord-005646-xhx9pzhj 3867 40 increased increase VBD cord-005646-xhx9pzhj 3868 1 , , , cord-005646-xhx9pzhj 3868 2 the the DT cord-005646-xhx9pzhj 3868 3 heart heart NN cord-005646-xhx9pzhj 3868 4 / / SYM cord-005646-xhx9pzhj 3868 5 chest chest NN cord-005646-xhx9pzhj 3868 6 dimension dimension NN cord-005646-xhx9pzhj 3868 7 ratio ratio NN cord-005646-xhx9pzhj 3868 8 decreased decrease VBD cord-005646-xhx9pzhj 3868 9 , , , cord-005646-xhx9pzhj 3868 10 the the DT cord-005646-xhx9pzhj 3868 11 ST ST NNP cord-005646-xhx9pzhj 3868 12 segment segment NN cord-005646-xhx9pzhj 3868 13 went go VBD cord-005646-xhx9pzhj 3868 14 down down RP cord-005646-xhx9pzhj 3868 15 , , , cord-005646-xhx9pzhj 3868 16 the the DT cord-005646-xhx9pzhj 3868 17 T T NNP cord-005646-xhx9pzhj 3868 18 wave wave NN cord-005646-xhx9pzhj 3868 19 became become VBD cord-005646-xhx9pzhj 3868 20 more more RBR cord-005646-xhx9pzhj 3868 21 flat flat JJ cord-005646-xhx9pzhj 3868 22 and and CC cord-005646-xhx9pzhj 3868 23 inverted inverted JJ cord-005646-xhx9pzhj 3868 24 . . . cord-005646-xhx9pzhj 3869 1 Between between IN cord-005646-xhx9pzhj 3869 2 1986 1986 CD cord-005646-xhx9pzhj 3869 3 and and CC cord-005646-xhx9pzhj 3869 4 1995 1995 CD cord-005646-xhx9pzhj 3869 5 23 23 CD cord-005646-xhx9pzhj 3869 6 neonates neonate NNS cord-005646-xhx9pzhj 3869 7 , , , cord-005646-xhx9pzhj 3869 8 aged aged JJ cord-005646-xhx9pzhj 3869 9 2 2 CD cord-005646-xhx9pzhj 3869 10 -23 -23 CD cord-005646-xhx9pzhj 3869 11 days day NNS cord-005646-xhx9pzhj 3869 12 ( ( -LRB- cord-005646-xhx9pzhj 3869 13 median median JJ cord-005646-xhx9pzhj 3869 14 5 5 CD cord-005646-xhx9pzhj 3869 15 ) ) -RRB- cord-005646-xhx9pzhj 3869 16 , , , cord-005646-xhx9pzhj 3869 17 weight weight NN cord-005646-xhx9pzhj 3869 18 2,38 2,38 CD cord-005646-xhx9pzhj 3869 19 -4 -4 CD cord-005646-xhx9pzhj 3869 20 kg kg NNS cord-005646-xhx9pzhj 3869 21 ( ( -LRB- cord-005646-xhx9pzhj 3869 22 median median NN cord-005646-xhx9pzhj 3869 23 3,28 3,28 CD cord-005646-xhx9pzhj 3869 24 ) ) -RRB- cord-005646-xhx9pzhj 3869 25 with with IN cord-005646-xhx9pzhj 3869 26 critical critical JJ cord-005646-xhx9pzhj 3869 27 valvar valvar NNP cord-005646-xhx9pzhj 3869 28 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3869 29 stenosis stenosis NN cord-005646-xhx9pzhj 3869 30 were be VBD cord-005646-xhx9pzhj 3869 31 scheduled schedule VBN cord-005646-xhx9pzhj 3869 32 for for IN cord-005646-xhx9pzhj 3869 33 balloon balloon NN cord-005646-xhx9pzhj 3869 34 dilation dilation NN cord-005646-xhx9pzhj 3869 35 ( ( -LRB- cord-005646-xhx9pzhj 3869 36 PSVP PSVP NNP cord-005646-xhx9pzhj 3869 37 ) ) -RRB- cord-005646-xhx9pzhj 3869 38 , , , cord-005646-xhx9pzhj 3869 39 19 19 CD cord-005646-xhx9pzhj 3869 40 children child NNS cord-005646-xhx9pzhj 3869 41 ( ( -LRB- cord-005646-xhx9pzhj 3869 42 83 83 CD cord-005646-xhx9pzhj 3869 43 % % NN cord-005646-xhx9pzhj 3869 44 ) ) -RRB- cord-005646-xhx9pzhj 3869 45 were be VBD cord-005646-xhx9pzhj 3869 46 on on IN cord-005646-xhx9pzhj 3869 47 PGE1 PGE1 NNP cord-005646-xhx9pzhj 3869 48 and and CC cord-005646-xhx9pzhj 3869 49 13 13 CD cord-005646-xhx9pzhj 3869 50 ( ( -LRB- cord-005646-xhx9pzhj 3869 51 57 57 CD cord-005646-xhx9pzhj 3869 52 % % NN cord-005646-xhx9pzhj 3869 53 ) ) -RRB- cord-005646-xhx9pzhj 3869 54 needed need VBD cord-005646-xhx9pzhj 3869 55 mechanical mechanical JJ cord-005646-xhx9pzhj 3869 56 ventilation ventilation NN cord-005646-xhx9pzhj 3869 57 . . . cord-005646-xhx9pzhj 3870 1 After after IN cord-005646-xhx9pzhj 3870 2 stepwise stepwise JJ cord-005646-xhx9pzhj 3870 3 dilation dilation NN cord-005646-xhx9pzhj 3870 4 a a DT cord-005646-xhx9pzhj 3870 5 final final JJ cord-005646-xhx9pzhj 3870 6 balloon balloon NN cord-005646-xhx9pzhj 3870 7 : : : cord-005646-xhx9pzhj 3871 1 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3871 2 valve valve NN cord-005646-xhx9pzhj 3871 3 ( ( -LRB- cord-005646-xhx9pzhj 3871 4 PaV PaV NNP cord-005646-xhx9pzhj 3871 5 ) ) -RRB- cord-005646-xhx9pzhj 3871 6 ratio ratio NN cord-005646-xhx9pzhj 3871 7 of of IN cord-005646-xhx9pzhj 3871 8 114 114 CD cord-005646-xhx9pzhj 3871 9 % % NN cord-005646-xhx9pzhj 3871 10 ( ( -LRB- cord-005646-xhx9pzhj 3871 11 25 25 CD cord-005646-xhx9pzhj 3871 12 - - SYM cord-005646-xhx9pzhj 3871 13 150 150 CD cord-005646-xhx9pzhj 3871 14 ) ) -RRB- cord-005646-xhx9pzhj 3871 15 was be VBD cord-005646-xhx9pzhj 3871 16 achieved achieve VBN cord-005646-xhx9pzhj 3871 17 , , , cord-005646-xhx9pzhj 3871 18 There there EX cord-005646-xhx9pzhj 3871 19 was be VBD cord-005646-xhx9pzhj 3871 20 a a DT cord-005646-xhx9pzhj 3871 21 significant significant JJ cord-005646-xhx9pzhj 3871 22 correlation correlation NN cord-005646-xhx9pzhj 3871 23 ( ( -LRB- cord-005646-xhx9pzhj 3871 24 p<0,01 p<0,01 NN cord-005646-xhx9pzhj 3871 25 ) ) -RRB- cord-005646-xhx9pzhj 3871 26 between between IN cord-005646-xhx9pzhj 3871 27 an an DT cord-005646-xhx9pzhj 3871 28 adequately adequately RB cord-005646-xhx9pzhj 3871 29 sized sized JJ cord-005646-xhx9pzhj 3871 30 balloon balloon NN cord-005646-xhx9pzhj 3871 31 and and CC cord-005646-xhx9pzhj 3871 32 freedom freedom NN cord-005646-xhx9pzhj 3871 33 of of IN cord-005646-xhx9pzhj 3871 34 reintervention reintervention NN cord-005646-xhx9pzhj 3871 35 . . . cord-005646-xhx9pzhj 3872 1 Two two CD cord-005646-xhx9pzhj 3872 2 valves valve NNS cord-005646-xhx9pzhj 3872 3 could could MD cord-005646-xhx9pzhj 3872 4 not not RB cord-005646-xhx9pzhj 3872 5 be be VB cord-005646-xhx9pzhj 3872 6 passed pass VBN cord-005646-xhx9pzhj 3872 7 , , , cord-005646-xhx9pzhj 3872 8 four four CD cord-005646-xhx9pzhj 3872 9 neonates neonate NNS cord-005646-xhx9pzhj 3872 10 underwent undergo VBD cord-005646-xhx9pzhj 3872 11 surgical surgical JJ cord-005646-xhx9pzhj 3872 12 procedures procedure NNS cord-005646-xhx9pzhj 3873 1 ( ( -LRB- cord-005646-xhx9pzhj 3873 2 brock brock NNP cord-005646-xhx9pzhj 3873 3 n n NNP cord-005646-xhx9pzhj 3873 4 = = SYM cord-005646-xhx9pzhj 3873 5 3 3 CD cord-005646-xhx9pzhj 3873 6 , , , cord-005646-xhx9pzhj 3873 7 commissurotomy commissurotomy NN cord-005646-xhx9pzhj 3873 8 n n NN cord-005646-xhx9pzhj 3873 9 = = SYM cord-005646-xhx9pzhj 3873 10 1 1 CD cord-005646-xhx9pzhj 3873 11 ) ) -RRB- cord-005646-xhx9pzhj 3873 12 , , , cord-005646-xhx9pzhj 3873 13 two two CD cord-005646-xhx9pzhj 3873 14 children child NNS cord-005646-xhx9pzhj 3873 15 ( ( -LRB- cord-005646-xhx9pzhj 3873 16 10 10 CD cord-005646-xhx9pzhj 3873 17 % % NN cord-005646-xhx9pzhj 3873 18 ) ) -RRB- cord-005646-xhx9pzhj 3873 19 died die VBD cord-005646-xhx9pzhj 3873 20 of of IN cord-005646-xhx9pzhj 3873 21 sepsis sepsis NN cord-005646-xhx9pzhj 3873 22 . . . cord-005646-xhx9pzhj 3874 1 17/23 17/23 CD cord-005646-xhx9pzhj 3874 2 patients patient NNS cord-005646-xhx9pzhj 3874 3 ( ( -LRB- cord-005646-xhx9pzhj 3874 4 73 73 CD cord-005646-xhx9pzhj 3874 5 % % NN cord-005646-xhx9pzhj 3874 6 ) ) -RRB- cord-005646-xhx9pzhj 3874 7 were be VBD cord-005646-xhx9pzhj 3874 8 successfully successfully RB cord-005646-xhx9pzhj 3874 9 palliated palliate VBN cord-005646-xhx9pzhj 3874 10 by by IN cord-005646-xhx9pzhj 3874 11 PSVP PSVP NNP cord-005646-xhx9pzhj 3874 12 in in IN cord-005646-xhx9pzhj 3874 13 the the DT cord-005646-xhx9pzhj 3874 14 first first JJ cord-005646-xhx9pzhj 3874 15 month month NN cord-005646-xhx9pzhj 3874 16 of of IN cord-005646-xhx9pzhj 3874 17 life life NN cord-005646-xhx9pzhj 3874 18 . . . cord-005646-xhx9pzhj 3875 1 The the DT cord-005646-xhx9pzhj 3875 2 RV RV NNP cord-005646-xhx9pzhj 3875 3 : : : cord-005646-xhx9pzhj 3875 4 systemic systemic JJ cord-005646-xhx9pzhj 3875 5 pressure pressure NN cord-005646-xhx9pzhj 3875 6 value value NN cord-005646-xhx9pzhj 3875 7 fell fall VBD cord-005646-xhx9pzhj 3875 8 from from IN cord-005646-xhx9pzhj 3875 9 132 132 CD cord-005646-xhx9pzhj 3875 10 % % NN cord-005646-xhx9pzhj 3875 11 ( ( -LRB- cord-005646-xhx9pzhj 3875 12 75 75 CD cord-005646-xhx9pzhj 3875 13 - - SYM cord-005646-xhx9pzhj 3875 14 231 231 CD cord-005646-xhx9pzhj 3875 15 ) ) -RRB- cord-005646-xhx9pzhj 3875 16 to to IN cord-005646-xhx9pzhj 3875 17 58 58 CD cord-005646-xhx9pzhj 3875 18 % % NN cord-005646-xhx9pzhj 3875 19 ( ( -LRB- cord-005646-xhx9pzhj 3875 20 40 40 CD cord-005646-xhx9pzhj 3875 21 - - SYM cord-005646-xhx9pzhj 3875 22 87 87 CD cord-005646-xhx9pzhj 3875 23 ) ) -RRB- cord-005646-xhx9pzhj 3875 24 , , , cord-005646-xhx9pzhj 3875 25 Complications complication NNS cord-005646-xhx9pzhj 3875 26 included include VBD cord-005646-xhx9pzhj 3875 27 2 2 CD cord-005646-xhx9pzhj 3875 28 transient transient JJ cord-005646-xhx9pzhj 3875 29 dysrhythmias dysrhythmia NNS cord-005646-xhx9pzhj 3875 30 , , , cord-005646-xhx9pzhj 3875 31 1 1 CD cord-005646-xhx9pzhj 3875 32 transient transient JJ cord-005646-xhx9pzhj 3875 33 hypoxia hypoxia NN cord-005646-xhx9pzhj 3875 34 , , , cord-005646-xhx9pzhj 3875 35 3 3 CD cord-005646-xhx9pzhj 3875 36 vessel vessel NN cord-005646-xhx9pzhj 3875 37 occlusions;-1 occlusions;-1 NN cord-005646-xhx9pzhj 3875 38 right right JJ cord-005646-xhx9pzhj 3875 39 ventricular ventricular JJ cord-005646-xhx9pzhj 3875 40 outflow outflow JJ cord-005646-xhx9pzhj 3875 41 tract tract NN cord-005646-xhx9pzhj 3875 42 perforation perforation NN cord-005646-xhx9pzhj 3875 43 . . . cord-005646-xhx9pzhj 3876 1 In in IN cord-005646-xhx9pzhj 3876 2 16/17 16/17 CD cord-005646-xhx9pzhj 3876 3 patients patient NNS cord-005646-xhx9pzhj 3876 4 follow follow VBP cord-005646-xhx9pzhj 3876 5 up up RP cord-005646-xhx9pzhj 3876 6 data datum NNS cord-005646-xhx9pzhj 3876 7 is be VBZ cord-005646-xhx9pzhj 3876 8 available available JJ cord-005646-xhx9pzhj 3876 9 . . . cord-005646-xhx9pzhj 3877 1 The the DT cord-005646-xhx9pzhj 3877 2 residual residual JJ cord-005646-xhx9pzhj 3877 3 systolic systolic JJ cord-005646-xhx9pzhj 3877 4 peak peak NN cord-005646-xhx9pzhj 3877 5 doppler doppler NN cord-005646-xhx9pzhj 3877 6 gradient gradient NN cord-005646-xhx9pzhj 3877 7 over over IN cord-005646-xhx9pzhj 3877 8 the the DT cord-005646-xhx9pzhj 3877 9 PaV pav NN cord-005646-xhx9pzhj 3877 10 on on IN cord-005646-xhx9pzhj 3877 11 the the DT cord-005646-xhx9pzhj 3877 12 last last JJ cord-005646-xhx9pzhj 3877 13 out out RP cord-005646-xhx9pzhj 3877 14 patient patient NN cord-005646-xhx9pzhj 3877 15 visit visit NN cord-005646-xhx9pzhj 3877 16 ( ( -LRB- cord-005646-xhx9pzhj 3877 17 5 5 CD cord-005646-xhx9pzhj 3877 18 - - SYM cord-005646-xhx9pzhj 3877 19 103 103 CD cord-005646-xhx9pzhj 3877 20 months month NNS cord-005646-xhx9pzhj 3877 21 after after IN cord-005646-xhx9pzhj 3877 22 PSVP PSVP NNP cord-005646-xhx9pzhj 3877 23 ) ) -RRB- cord-005646-xhx9pzhj 3877 24 was be VBD cord-005646-xhx9pzhj 3877 25 10 10 CD cord-005646-xhx9pzhj 3877 26 - - SYM cord-005646-xhx9pzhj 3877 27 41 41 CD cord-005646-xhx9pzhj 3877 28 mmHg mmHg NNS cord-005646-xhx9pzhj 3877 29 ( ( -LRB- cord-005646-xhx9pzhj 3877 30 median median JJ cord-005646-xhx9pzhj 3877 31 20 20 CD cord-005646-xhx9pzhj 3877 32 ) ) -RRB- cord-005646-xhx9pzhj 3877 33 . . . cord-005646-xhx9pzhj 3878 1 Four four CD cord-005646-xhx9pzhj 3878 2 children child NNS cord-005646-xhx9pzhj 3878 3 needed need VBD cord-005646-xhx9pzhj 3878 4 repea.ted repea.ted NNP cord-005646-xhx9pzhj 3878 5 PSVP PSVP NNP cord-005646-xhx9pzhj 3878 6 26 26 CD cord-005646-xhx9pzhj 3878 7 to to TO cord-005646-xhx9pzhj 3878 8 72 72 CD cord-005646-xhx9pzhj 3878 9 months month NNS cord-005646-xhx9pzhj 3878 10 after after IN cord-005646-xhx9pzhj 3878 11 the the DT cord-005646-xhx9pzhj 3878 12 initial initial JJ cord-005646-xhx9pzhj 3878 13 intervention intervention NN cord-005646-xhx9pzhj 3878 14 . . . cord-005646-xhx9pzhj 3879 1 Conclusion conclusion NN cord-005646-xhx9pzhj 3879 2 : : : cord-005646-xhx9pzhj 3879 3 PSVP PSVP NNP cord-005646-xhx9pzhj 3879 4 of of IN cord-005646-xhx9pzhj 3879 5 critically critically RB cord-005646-xhx9pzhj 3879 6 ill ill JJ cord-005646-xhx9pzhj 3879 7 newborns newborn NNS cord-005646-xhx9pzhj 3879 8 is be VBZ cord-005646-xhx9pzhj 3879 9 possible possible JJ cord-005646-xhx9pzhj 3879 10 . . . cord-005646-xhx9pzhj 3880 1 The the DT cord-005646-xhx9pzhj 3880 2 risk risk NN cord-005646-xhx9pzhj 3880 3 of of IN cord-005646-xhx9pzhj 3880 4 mortality mortality NN cord-005646-xhx9pzhj 3880 5 is be VBZ cord-005646-xhx9pzhj 3880 6 relatively relatively RB cord-005646-xhx9pzhj 3880 7 low low JJ cord-005646-xhx9pzhj 3880 8 . . . cord-005646-xhx9pzhj 3881 1 PSVP PSVP NNP cord-005646-xhx9pzhj 3881 2 in in IN cord-005646-xhx9pzhj 3881 3 neonates neonate NNS cord-005646-xhx9pzhj 3881 4 with with IN cord-005646-xhx9pzhj 3881 5 an an DT cord-005646-xhx9pzhj 3881 6 adequately adequately RB cord-005646-xhx9pzhj 3881 7 sized sized JJ cord-005646-xhx9pzhj 3881 8 balloon balloon NN cord-005646-xhx9pzhj 3881 9 is be VBZ cord-005646-xhx9pzhj 3881 10 a a DT cord-005646-xhx9pzhj 3881 11 challenging challenging JJ cord-005646-xhx9pzhj 3881 12 alternative alternative NN cord-005646-xhx9pzhj 3881 13 to to IN cord-005646-xhx9pzhj 3881 14 surgical surgical JJ cord-005646-xhx9pzhj 3881 15 treatment treatment NN cord-005646-xhx9pzhj 3881 16 . . . cord-005646-xhx9pzhj 3882 1 Post post JJ cord-005646-xhx9pzhj 3882 2 hypoxic hypoxic JJ cord-005646-xhx9pzhj 3882 3 - - HYPH cord-005646-xhx9pzhj 3882 4 ischemic ischemic JJ cord-005646-xhx9pzhj 3882 5 ( ( -LRB- cord-005646-xhx9pzhj 3882 6 HI hi UH cord-005646-xhx9pzhj 3882 7 ) ) -RRB- cord-005646-xhx9pzhj 3882 8 reperfusion reperfusion NN cord-005646-xhx9pzhj 3882 9 induces induce VBZ cord-005646-xhx9pzhj 3882 10 the the DT cord-005646-xhx9pzhj 3882 11 formation formation NN cord-005646-xhx9pzhj 3882 12 of of IN cord-005646-xhx9pzhj 3882 13 non non JJ cord-005646-xhx9pzhj 3882 14 protein protein NN cord-005646-xhx9pzhj 3882 15 bound bind VBN cord-005646-xhx9pzhj 3882 16 iron iron NN cord-005646-xhx9pzhj 3882 17 ( ( -LRB- cord-005646-xhx9pzhj 3882 18 NPBI NPBI NNP cord-005646-xhx9pzhj 3882 19 ) ) -RRB- cord-005646-xhx9pzhj 3882 20 , , , cord-005646-xhx9pzhj 3882 21 leading lead VBG cord-005646-xhx9pzhj 3882 22 to to IN cord-005646-xhx9pzhj 3882 23 production production NN cord-005646-xhx9pzhj 3882 24 of of IN cord-005646-xhx9pzhj 3882 25 the the DT cord-005646-xhx9pzhj 3882 26 reactive reactive JJ cord-005646-xhx9pzhj 3882 27 hydroxyl hydroxyl NN cord-005646-xhx9pzhj 3882 28 radical radical JJ cord-005646-xhx9pzhj 3882 29 . . . cord-005646-xhx9pzhj 3883 1 It -PRON- PRP cord-005646-xhx9pzhj 3883 2 was be VBD cord-005646-xhx9pzhj 3883 3 investigated investigate VBN cord-005646-xhx9pzhj 3883 4 if if IN cord-005646-xhx9pzhj 3883 5 the the DT cord-005646-xhx9pzhj 3883 6 ironchelator ironchelator NNP cord-005646-xhx9pzhj 3883 7 deferoxamine deferoxamine NNP cord-005646-xhx9pzhj 3883 8 ( ( -LRB- cord-005646-xhx9pzhj 3883 9 DFO DFO NNP cord-005646-xhx9pzhj 3883 10 ) ) -RRB- cord-005646-xhx9pzhj 3883 11 could could MD cord-005646-xhx9pzhj 3883 12 reduce reduce VB cord-005646-xhx9pzhj 3883 13 free free JJ cord-005646-xhx9pzhj 3883 14 radical radical JJ cord-005646-xhx9pzhj 3883 15 production production NN cord-005646-xhx9pzhj 3883 16 and and CC cord-005646-xhx9pzhj 3883 17 improve improve VB cord-005646-xhx9pzhj 3883 18 neonatal neonatal JJ cord-005646-xhx9pzhj 3883 19 myocardial myocardial JJ cord-005646-xhx9pzhj 3883 20 performance performance NN cord-005646-xhx9pzhj 3883 21 after after IN cord-005646-xhx9pzhj 3883 22 HI HI NNP cord-005646-xhx9pzhj 3883 23 . . . cord-005646-xhx9pzhj 3884 1 Severe severe JJ cord-005646-xhx9pzhj 3884 2 HI HI NNP cord-005646-xhx9pzhj 3884 3 was be VBD cord-005646-xhx9pzhj 3884 4 produced produce VBN cord-005646-xhx9pzhj 3884 5 in in IN cord-005646-xhx9pzhj 3884 6 13 13 CD cord-005646-xhx9pzhj 3884 7 newborn newborn JJ cord-005646-xhx9pzhj 3884 8 lambs lamb NNS cord-005646-xhx9pzhj 3884 9 and and CC cord-005646-xhx9pzhj 3884 10 changes change NNS cord-005646-xhx9pzhj 3884 11 from from IN cord-005646-xhx9pzhj 3884 12 pre pre JJ cord-005646-xhx9pzhj 3884 13 - - JJ cord-005646-xhx9pzhj 3884 14 Hl hl JJ cord-005646-xhx9pzhj 3884 15 values value NNS cord-005646-xhx9pzhj 3884 16 were be VBD cord-005646-xhx9pzhj 3884 17 measured measure VBN cord-005646-xhx9pzhj 3884 18 at at IN cord-005646-xhx9pzhj 3884 19 15 15 CD cord-005646-xhx9pzhj 3884 20 , , , cord-005646-xhx9pzhj 3884 21 60 60 CD cord-005646-xhx9pzhj 3884 22 and and CC cord-005646-xhx9pzhj 3884 23 120 120 CD cord-005646-xhx9pzhj 3884 24 min min NN cord-005646-xhx9pzhj 3884 25 post post NN cord-005646-xhx9pzhj 3884 26 - - NN cord-005646-xhx9pzhj 3884 27 HI HI NNP cord-005646-xhx9pzhj 3884 28 for for IN cord-005646-xhx9pzhj 3884 29 ( ( -LRB- cord-005646-xhx9pzhj 3884 30 mean mean VB cord-005646-xhx9pzhj 3884 31 ) ) -RRB- cord-005646-xhx9pzhj 3884 32 aortic aortic JJ cord-005646-xhx9pzhj 3884 33 pressure pressure NN cord-005646-xhx9pzhj 3884 34 ( ( -LRB- cord-005646-xhx9pzhj 3884 35 mean mean VB cord-005646-xhx9pzhj 3884 36 Pao Pao NNP cord-005646-xhx9pzhj 3884 37 ) ) -RRB- cord-005646-xhx9pzhj 3884 38 , , , cord-005646-xhx9pzhj 3884 39 cardiac cardiac JJ cord-005646-xhx9pzhj 3884 40 output output NN cord-005646-xhx9pzhj 3884 41 ( ( -LRB- cord-005646-xhx9pzhj 3884 42 CO co NN cord-005646-xhx9pzhj 3884 43 ) ) -RRB- cord-005646-xhx9pzhj 3884 44 and and CC cord-005646-xhx9pzhj 3884 45 stroke stroke NN cord-005646-xhx9pzhj 3884 46 work work NN cord-005646-xhx9pzhj 3884 47 ( ( -LRB- cord-005646-xhx9pzhj 3884 48 SW SW NNP cord-005646-xhx9pzhj 3884 49 ) ) -RRB- cord-005646-xhx9pzhj 3884 50 . . . cord-005646-xhx9pzhj 3885 1 Left leave VBN cord-005646-xhx9pzhj 3885 2 ventricular ventricular JJ cord-005646-xhx9pzhj 3885 3 ( ( -LRB- cord-005646-xhx9pzhj 3885 4 LV LV NNP cord-005646-xhx9pzhj 3885 5 ) ) -RRB- cord-005646-xhx9pzhj 3885 6 contractility contractility NN cord-005646-xhx9pzhj 3885 7 and and CC cord-005646-xhx9pzhj 3885 8 CO CO NNP cord-005646-xhx9pzhj 3885 9 were be VBD cord-005646-xhx9pzhj 3885 10 assessed assess VBN cord-005646-xhx9pzhj 3885 11 by by IN cord-005646-xhx9pzhj 3885 12 measuring measure VBG cord-005646-xhx9pzhj 3885 13 LV LV NNP cord-005646-xhx9pzhj 3885 14 pressure pressure NN cord-005646-xhx9pzhj 3885 15 ( ( -LRB- cord-005646-xhx9pzhj 3885 16 tip tip NN cord-005646-xhx9pzhj 3885 17 - - HYPH cord-005646-xhx9pzhj 3885 18 manometer manometer NN cord-005646-xhx9pzhj 3885 19 ) ) -RRB- cord-005646-xhx9pzhj 3885 20 and and CC cord-005646-xhx9pzhj 3885 21 volume volume NN cord-005646-xhx9pzhj 3885 22 ( ( -LRB- cord-005646-xhx9pzhj 3885 23 conductance conductance NN cord-005646-xhx9pzhj 3885 24 catheter catheter NN cord-005646-xhx9pzhj 3885 25 ) ) -RRB- cord-005646-xhx9pzhj 3885 26 , , , cord-005646-xhx9pzhj 3885 27 using use VBG cord-005646-xhx9pzhj 3885 28 inferior inferior JJ cord-005646-xhx9pzhj 3885 29 caval caval NN cord-005646-xhx9pzhj 3885 30 vein vein NN cord-005646-xhx9pzhj 3885 31 occlusion occlusion NN cord-005646-xhx9pzhj 3885 32 to to TO cord-005646-xhx9pzhj 3885 33 obtain obtain VB cord-005646-xhx9pzhj 3885 34 slope slope NN cord-005646-xhx9pzhj 3885 35 ( ( -LRB- cord-005646-xhx9pzhj 3885 36 Ees Ees NNP cord-005646-xhx9pzhj 3885 37 ) ) -RRB- cord-005646-xhx9pzhj 3885 38 and and CC cord-005646-xhx9pzhj 3885 39 intercept intercept VB cord-005646-xhx9pzhj 3885 40 of of IN cord-005646-xhx9pzhj 3885 41 the the DT cord-005646-xhx9pzhj 3885 42 end end NN cord-005646-xhx9pzhj 3885 43 systolic systolic JJ cord-005646-xhx9pzhj 3885 44 PV pv NN cord-005646-xhx9pzhj 3885 45 relationship relationship NN cord-005646-xhx9pzhj 3885 46 ( ( -LRB- cord-005646-xhx9pzhj 3885 47 V10 V10 NNP cord-005646-xhx9pzhj 3885 48 ) ) -RRB- cord-005646-xhx9pzhj 3885 49 . . . cord-005646-xhx9pzhj 3886 1 NPBI NPBI NNP cord-005646-xhx9pzhj 3886 2 , , , cord-005646-xhx9pzhj 3886 3 reduced reduce VBN cord-005646-xhx9pzhj 3886 4 and and CC cord-005646-xhx9pzhj 3886 5 oxidized oxidize VBN cord-005646-xhx9pzhj 3886 6 vitamine vitamine NN cord-005646-xhx9pzhj 3886 7 C c NN cord-005646-xhx9pzhj 3886 8 ratio ratio NN cord-005646-xhx9pzhj 3886 9 ( ( -LRB- cord-005646-xhx9pzhj 3886 10 VCred VCred NNP cord-005646-xhx9pzhj 3886 11 / / SYM cord-005646-xhx9pzhj 3886 12 ox ox NN cord-005646-xhx9pzhj 3886 13 ) ) -RRB- cord-005646-xhx9pzhj 3886 14 and and CC cord-005646-xhx9pzhj 3886 15 lipid lipid NN cord-005646-xhx9pzhj 3886 16 peroxidation peroxidation NN cord-005646-xhx9pzhj 3886 17 ( ( -LRB- cord-005646-xhx9pzhj 3886 18 MDA MDA NNP cord-005646-xhx9pzhj 3886 19 ) ) -RRB- cord-005646-xhx9pzhj 3886 20 were be VBD cord-005646-xhx9pzhj 3886 21 measured measure VBN cord-005646-xhx9pzhj 3886 22 from from IN cord-005646-xhx9pzhj 3886 23 sinus sinus NN cord-005646-xhx9pzhj 3886 24 coronarius coronarius NNP cord-005646-xhx9pzhj 3886 25 blood blood NN cord-005646-xhx9pzhj 3886 26 . . . cord-005646-xhx9pzhj 3887 1 7 7 CD cord-005646-xhx9pzhj 3887 2 Lambs Lambs NNP cord-005646-xhx9pzhj 3887 3 received receive VBD cord-005646-xhx9pzhj 3887 4 DFO DFO NNP cord-005646-xhx9pzhj 3887 5 ( ( -LRB- cord-005646-xhx9pzhj 3887 6 10 10 CD cord-005646-xhx9pzhj 3887 7 mg mg NNP cord-005646-xhx9pzhj 3887 8 / / SYM cord-005646-xhx9pzhj 3887 9 kg kg NNP cord-005646-xhx9pzhj 3887 10 i.v i.v NNP cord-005646-xhx9pzhj 3887 11 . . . cord-005646-xhx9pzhj 3887 12 ) ) -RRB- cord-005646-xhx9pzhj 3888 1 immediately immediately RB cord-005646-xhx9pzhj 3888 2 post post VB cord-005646-xhx9pzhj 3888 3 - - NN cord-005646-xhx9pzhj 3888 4 HI hi JJ cord-005646-xhx9pzhj 3888 5 , , , cord-005646-xhx9pzhj 3888 6 control control NN cord-005646-xhx9pzhj 3888 7 lambs lamb NNS cord-005646-xhx9pzhj 3888 8 ( ( -LRB- cord-005646-xhx9pzhj 3888 9 CONT CONT NNP cord-005646-xhx9pzhj 3888 10 ) ) -RRB- cord-005646-xhx9pzhj 3888 11 received receive VBD cord-005646-xhx9pzhj 3888 12 a a DT cord-005646-xhx9pzhj 3888 13 placebo placebo NN cord-005646-xhx9pzhj 3888 14 . . . cord-005646-xhx9pzhj 3889 1 Results result NNS cord-005646-xhx9pzhj 3889 2 : : : cord-005646-xhx9pzhj 3890 1 Mean mean JJ cord-005646-xhx9pzhj 3890 2 Pao Pao NNP cord-005646-xhx9pzhj 3890 3 was be VBD cord-005646-xhx9pzhj 3890 4 stable stable JJ cord-005646-xhx9pzhj 3890 5 , , , cord-005646-xhx9pzhj 3890 6 CO CO NNP cord-005646-xhx9pzhj 3890 7 and and CC cord-005646-xhx9pzhj 3890 8 SW SW NNP cord-005646-xhx9pzhj 3890 9 decreased decrease VBD cord-005646-xhx9pzhj 3890 10 up up RP cord-005646-xhx9pzhj 3890 11 to to TO cord-005646-xhx9pzhj 3890 12 60 60 CD cord-005646-xhx9pzhj 3890 13 and and CC cord-005646-xhx9pzhj 3890 14 40 40 CD cord-005646-xhx9pzhj 3890 15 % % NN cord-005646-xhx9pzhj 3890 16 respectively respectively RB cord-005646-xhx9pzhj 3890 17 in in IN cord-005646-xhx9pzhj 3890 18 CONT CONT NNP cord-005646-xhx9pzhj 3890 19 as as IN cord-005646-xhx9pzhj 3890 20 compared compare VBN cord-005646-xhx9pzhj 3890 21 to to IN cord-005646-xhx9pzhj 3890 22 pre pre JJ cord-005646-xhx9pzhj 3890 23 - - NN cord-005646-xhx9pzhj 3890 24 HI HI NNP cord-005646-xhx9pzhj 3890 25 . . . cord-005646-xhx9pzhj 3891 1 In in IN cord-005646-xhx9pzhj 3891 2 both both DT cord-005646-xhx9pzhj 3891 3 DFO DFO NNP cord-005646-xhx9pzhj 3891 4 - - HYPH cord-005646-xhx9pzhj 3891 5 groups group NNS cord-005646-xhx9pzhj 3891 6 CO CO NNP cord-005646-xhx9pzhj 3891 7 and and CC cord-005646-xhx9pzhj 3891 8 SW SW NNP cord-005646-xhx9pzhj 3891 9 remained remain VBD cord-005646-xhx9pzhj 3891 10 within within IN cord-005646-xhx9pzhj 3891 11 the the DT cord-005646-xhx9pzhj 3891 12 normal normal JJ cord-005646-xhx9pzhj 3891 13 range range NN cord-005646-xhx9pzhj 3891 14 . . . cord-005646-xhx9pzhj 3892 1 Ees Ees NNP cord-005646-xhx9pzhj 3892 2 and and CC cord-005646-xhx9pzhj 3892 3 V10 V10 NNP cord-005646-xhx9pzhj 3892 4 decreased decrease VBD cord-005646-xhx9pzhj 3892 5 in in IN cord-005646-xhx9pzhj 3892 6 all all DT cord-005646-xhx9pzhj 3892 7 groups group NNS cord-005646-xhx9pzhj 3892 8 post post VBP cord-005646-xhx9pzhj 3892 9 HI HI NNP cord-005646-xhx9pzhj 3892 10 , , , cord-005646-xhx9pzhj 3892 11 but but CC cord-005646-xhx9pzhj 3892 12 did do VBD cord-005646-xhx9pzhj 3892 13 not not RB cord-005646-xhx9pzhj 3892 14 differ differ VB cord-005646-xhx9pzhj 3892 15 between between IN cord-005646-xhx9pzhj 3892 16 groups group NNS cord-005646-xhx9pzhj 3892 17 . . . cord-005646-xhx9pzhj 3893 1 NPBI NPBI NNP cord-005646-xhx9pzhj 3893 2 and and CC cord-005646-xhx9pzhj 3893 3 MDA MDA NNP cord-005646-xhx9pzhj 3893 4 were be VBD cord-005646-xhx9pzhj 3893 5 higher high JJR cord-005646-xhx9pzhj 3893 6 at at IN cord-005646-xhx9pzhj 3893 7 15 15 CD cord-005646-xhx9pzhj 3893 8 min min NN cord-005646-xhx9pzhj 3893 9 post post NN cord-005646-xhx9pzhj 3894 1 HI HI NNP cord-005646-xhx9pzhj 3895 1 ( ( -LRB- cord-005646-xhx9pzhj 3895 2 p p NN cord-005646-xhx9pzhj 3895 3 < < XX cord-005646-xhx9pzhj 3895 4 O.05 o.05 JJ cord-005646-xhx9pzhj 3895 5 ) ) -RRB- cord-005646-xhx9pzhj 3895 6 , , , cord-005646-xhx9pzhj 3895 7 VCred VCred NNP cord-005646-xhx9pzhj 3895 8 / / SYM cord-005646-xhx9pzhj 3895 9 ox ox NN cord-005646-xhx9pzhj 3895 10 was be VBD cord-005646-xhx9pzhj 3895 11 lower low JJR cord-005646-xhx9pzhj 3895 12 at at IN cord-005646-xhx9pzhj 3895 13 15 15 CD cord-005646-xhx9pzhj 3895 14 min min NN cord-005646-xhx9pzhj 3895 15 post post NN cord-005646-xhx9pzhj 3895 16 - - NN cord-005646-xhx9pzhj 3895 17 HI hi JJ cord-005646-xhx9pzhj 3895 18 ( ( -LRB- cord-005646-xhx9pzhj 3895 19 p p NN cord-005646-xhx9pzhj 3895 20 < < XX cord-005646-xhx9pzhj 3895 21 O.O5 O.O5 NNP cord-005646-xhx9pzhj 3895 22 ) ) -RRB- cord-005646-xhx9pzhj 3895 23 in in IN cord-005646-xhx9pzhj 3895 24 CONT CONT NNP cord-005646-xhx9pzhj 3895 25 as as IN cord-005646-xhx9pzhj 3895 26 compared compare VBN cord-005646-xhx9pzhj 3895 27 to to IN cord-005646-xhx9pzhj 3895 28 DFO DFO NNP cord-005646-xhx9pzhj 3895 29 - - HYPH cord-005646-xhx9pzhj 3895 30 group group NN cord-005646-xhx9pzhj 3895 31 , , , cord-005646-xhx9pzhj 3895 32 indicating indicate VBG cord-005646-xhx9pzhj 3895 33 more more JJR cord-005646-xhx9pzhj 3895 34 oxidative oxidative JJ cord-005646-xhx9pzhj 3895 35 stress stress NN cord-005646-xhx9pzhj 3895 36 in in IN cord-005646-xhx9pzhj 3895 37 CONT CONT NNP cord-005646-xhx9pzhj 3895 38 . . . cord-005646-xhx9pzhj 3896 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 3896 2 : : : cord-005646-xhx9pzhj 3897 1 DFO DFO NNP cord-005646-xhx9pzhj 3897 2 reduced reduce VBD cord-005646-xhx9pzhj 3897 3 the the DT cord-005646-xhx9pzhj 3897 4 oxidative oxidative JJ cord-005646-xhx9pzhj 3897 5 stress stress NN cord-005646-xhx9pzhj 3897 6 of of IN cord-005646-xhx9pzhj 3897 7 the the DT cord-005646-xhx9pzhj 3897 8 heart heart NN cord-005646-xhx9pzhj 3897 9 and and CC cord-005646-xhx9pzhj 3897 10 prevented prevent VBD cord-005646-xhx9pzhj 3897 11 CO CO NNP cord-005646-xhx9pzhj 3897 12 and and CC cord-005646-xhx9pzhj 3897 13 SW SW NNP cord-005646-xhx9pzhj 3897 14 to to TO cord-005646-xhx9pzhj 3897 15 drop drop VB cord-005646-xhx9pzhj 3897 16 , , , cord-005646-xhx9pzhj 3897 17 suggesting suggest VBG cord-005646-xhx9pzhj 3897 18 a a DT cord-005646-xhx9pzhj 3897 19 positive positive JJ cord-005646-xhx9pzhj 3897 20 effect effect NN cord-005646-xhx9pzhj 3897 21 of of IN cord-005646-xhx9pzhj 3897 22 iron iron NN cord-005646-xhx9pzhj 3897 23 chelation chelation NN cord-005646-xhx9pzhj 3897 24 on on IN cord-005646-xhx9pzhj 3897 25 the the DT cord-005646-xhx9pzhj 3897 26 myocardium myocardium NN cord-005646-xhx9pzhj 3897 27 after after IN cord-005646-xhx9pzhj 3897 28 H H NNP cord-005646-xhx9pzhj 3897 29 { { -LRB- cord-005646-xhx9pzhj 3897 30 . . . cord-005646-xhx9pzhj 3898 1 From from IN cord-005646-xhx9pzhj 3898 2 1987 1987 CD cord-005646-xhx9pzhj 3898 3 we -PRON- PRP cord-005646-xhx9pzhj 3898 4 published publish VBD cord-005646-xhx9pzhj 3898 5 reports report NNS cord-005646-xhx9pzhj 3898 6 with with IN cord-005646-xhx9pzhj 3898 7 analysis analysis NN cord-005646-xhx9pzhj 3898 8 of of IN cord-005646-xhx9pzhj 3898 9 performance performance NN cord-005646-xhx9pzhj 3898 10 of of IN cord-005646-xhx9pzhj 3898 11 the the DT cord-005646-xhx9pzhj 3898 12 heart heart NN cord-005646-xhx9pzhj 3898 13 as as IN cord-005646-xhx9pzhj 3898 14 a a DT cord-005646-xhx9pzhj 3898 15 whole whole JJ cord-005646-xhx9pzhj 3898 16 organ organ NN cord-005646-xhx9pzhj 3898 17 . . . cord-005646-xhx9pzhj 3899 1 While while IN cord-005646-xhx9pzhj 3899 2 analysing analyse VBG cord-005646-xhx9pzhj 3899 3 the the DT cord-005646-xhx9pzhj 3899 4 heart heart NN cord-005646-xhx9pzhj 3899 5 performance performance NN cord-005646-xhx9pzhj 3899 6 as as IN cord-005646-xhx9pzhj 3899 7 a a DT cord-005646-xhx9pzhj 3899 8 whole whole NN cord-005646-xhx9pzhj 3899 9 , , , cord-005646-xhx9pzhj 3899 10 we -PRON- PRP cord-005646-xhx9pzhj 3899 11 recognize recognize VBP cord-005646-xhx9pzhj 3899 12 three three CD cord-005646-xhx9pzhj 3899 13 block block NN cord-005646-xhx9pzhj 3899 14 in in IN cord-005646-xhx9pzhj 3899 15 it -PRON- PRP cord-005646-xhx9pzhj 3899 16 located locate VBN cord-005646-xhx9pzhj 3899 17 intrapericardially intrapericardially RB cord-005646-xhx9pzhj 3899 18 : : : cord-005646-xhx9pzhj 3900 1 l. l. NNP cord-005646-xhx9pzhj 3901 1 " " `` cord-005646-xhx9pzhj 3901 2 atrial"block atrial"block '' cord-005646-xhx9pzhj 3902 1 -left -left JJ cord-005646-xhx9pzhj 3902 2 ( ( -LRB- cord-005646-xhx9pzhj 3902 3 LA LA NNP cord-005646-xhx9pzhj 3902 4 ) ) -RRB- cord-005646-xhx9pzhj 3902 5 and and CC cord-005646-xhx9pzhj 3902 6 rigth rigth JJ cord-005646-xhx9pzhj 3902 7 ( ( -LRB- cord-005646-xhx9pzhj 3902 8 RA RA NNP cord-005646-xhx9pzhj 3902 9 ) ) -RRB- cord-005646-xhx9pzhj 3902 10 atriums atrium NNS cord-005646-xhx9pzhj 3902 11 ; ; : cord-005646-xhx9pzhj 3903 1 2."aorta 2."aorta CD cord-005646-xhx9pzhj 3903 2 - - HYPH cord-005646-xhx9pzhj 3903 3 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3903 4 " " '' cord-005646-xhx9pzhj 3903 5 block block NN cord-005646-xhx9pzhj 3903 6 - - HYPH cord-005646-xhx9pzhj 3903 7 aorta aorta NN cord-005646-xhx9pzhj 3903 8 ' ' '' cord-005646-xhx9pzhj 3903 9 bulb bulb NN cord-005646-xhx9pzhj 3903 10 ( ( -LRB- cord-005646-xhx9pzhj 3903 11 A a NN cord-005646-xhx9pzhj 3903 12 ) ) -RRB- cord-005646-xhx9pzhj 3903 13 and and CC cord-005646-xhx9pzhj 3903 14 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3903 15 artery(PA artery(pa NN cord-005646-xhx9pzhj 3903 16 ) ) -RRB- cord-005646-xhx9pzhj 3903 17 ; ; : cord-005646-xhx9pzhj 3903 18 3.ventricular 3.ventricular CD cord-005646-xhx9pzhj 3903 19 " " `` cord-005646-xhx9pzhj 3903 20 three three CD cord-005646-xhx9pzhj 3903 21 - - HYPH cord-005646-xhx9pzhj 3903 22 chambered chambered JJ cord-005646-xhx9pzhj 3903 23 " " '' cord-005646-xhx9pzhj 3903 24 block block NN cord-005646-xhx9pzhj 3903 25 ( ( -LRB- cord-005646-xhx9pzhj 3903 26 VB VB NNP cord-005646-xhx9pzhj 3903 27 ) ) -RRB- cord-005646-xhx9pzhj 3903 28 consisting consist VBG cord-005646-xhx9pzhj 3903 29 of of IN cord-005646-xhx9pzhj 3903 30 : : : cord-005646-xhx9pzhj 3903 31 -left -left : cord-005646-xhx9pzhj 3903 32 ( ( -LRB- cord-005646-xhx9pzhj 3903 33 LV LV NNP cord-005646-xhx9pzhj 3903 34 ) ) -RRB- cord-005646-xhx9pzhj 3903 35 and and CC cord-005646-xhx9pzhj 3903 36 right right JJ cord-005646-xhx9pzhj 3903 37 ( ( -LRB- cord-005646-xhx9pzhj 3903 38 RV rv NN cord-005646-xhx9pzhj 3903 39 ) ) -RRB- cord-005646-xhx9pzhj 3903 40 myocardial myocardial JJ cord-005646-xhx9pzhj 3903 41 chambers chamber NNS cord-005646-xhx9pzhj 3903 42 , , , cord-005646-xhx9pzhj 3903 43 both both CC cord-005646-xhx9pzhj 3903 44 frith frith NNP cord-005646-xhx9pzhj 3903 45 blood blood NN cord-005646-xhx9pzhj 3903 46 outflow outflow NN cord-005646-xhx9pzhj 3903 47 into into IN cord-005646-xhx9pzhj 3903 48 " " `` cord-005646-xhx9pzhj 3903 49 aorta aorta JJ cord-005646-xhx9pzhj 3903 50 - - HYPH cord-005646-xhx9pzhj 3903 51 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3903 52 " " '' cord-005646-xhx9pzhj 3903 53 block block NN cord-005646-xhx9pzhj 3903 54 vessels vessel NNS cord-005646-xhx9pzhj 3903 55 , , , cord-005646-xhx9pzhj 3903 56 and and CC cord-005646-xhx9pzhj 3903 57 -spongy -spongy JJ cord-005646-xhx9pzhj 3903 58 ( ( -LRB- cord-005646-xhx9pzhj 3903 59 venous venous JJ cord-005646-xhx9pzhj 3903 60 ) ) -RRB- cord-005646-xhx9pzhj 3903 61 myocardial myocardial JJ cord-005646-xhx9pzhj 3903 62 chamber chamber NN cord-005646-xhx9pzhj 3903 63 with with IN cord-005646-xhx9pzhj 3903 64 the the DT cord-005646-xhx9pzhj 3903 65 blood blood NN cord-005646-xhx9pzhj 3903 66 outflow outflow NN cord-005646-xhx9pzhj 3903 67 through through IN cord-005646-xhx9pzhj 3903 68 coronary coronary JJ cord-005646-xhx9pzhj 3903 69 sinus sinus NN cord-005646-xhx9pzhj 3903 70 ( ( -LRB- cord-005646-xhx9pzhj 3903 71 CS CS NNP cord-005646-xhx9pzhj 3903 72 ) ) -RRB- cord-005646-xhx9pzhj 3903 73 and and CC cord-005646-xhx9pzhj 3903 74 Thebesiau Thebesiau NNP cord-005646-xhx9pzhj 3903 75 vein vein NN cord-005646-xhx9pzhj 3903 76 ( ( -LRB- cord-005646-xhx9pzhj 3903 77 TV tv NN cord-005646-xhx9pzhj 3903 78 ) ) -RRB- cord-005646-xhx9pzhj 3903 79 into into IN cord-005646-xhx9pzhj 3903 80 " " `` cord-005646-xhx9pzhj 3903 81 atrial atrial JJ cord-005646-xhx9pzhj 3903 82 " " '' cord-005646-xhx9pzhj 3903 83 block block NN cord-005646-xhx9pzhj 3903 84 . . . cord-005646-xhx9pzhj 3904 1 The the DT cord-005646-xhx9pzhj 3904 2 following follow VBG cord-005646-xhx9pzhj 3904 3 conceps concep NNS cord-005646-xhx9pzhj 3904 4 are be VBP cord-005646-xhx9pzhj 3904 5 introduced introduce VBN cord-005646-xhx9pzhj 3904 6 for for IN cord-005646-xhx9pzhj 3904 7 VB VB NNP cord-005646-xhx9pzhj 3904 8 functions function NNS cord-005646-xhx9pzhj 3904 9 assessment assessment NN cord-005646-xhx9pzhj 3904 10 " " `` cord-005646-xhx9pzhj 3904 11 common common JJ cord-005646-xhx9pzhj 3904 12 " " '' cord-005646-xhx9pzhj 3904 13 systole systole NN cord-005646-xhx9pzhj 3904 14 and and CC cord-005646-xhx9pzhj 3904 15 " " `` cord-005646-xhx9pzhj 3904 16 common common JJ cord-005646-xhx9pzhj 3904 17 " " '' cord-005646-xhx9pzhj 3904 18 diastole diastole NN cord-005646-xhx9pzhj 3904 19 of of IN cord-005646-xhx9pzhj 3904 20 " " `` cord-005646-xhx9pzhj 3904 21 three three CD cord-005646-xhx9pzhj 3904 22 - - HYPH cord-005646-xhx9pzhj 3904 23 chambered chambered JJ cord-005646-xhx9pzhj 3904 24 " " '' cord-005646-xhx9pzhj 3904 25 VB vb NN cord-005646-xhx9pzhj 3904 26 . . . cord-005646-xhx9pzhj 3905 1 The the DT cord-005646-xhx9pzhj 3905 2 process process NN cord-005646-xhx9pzhj 3905 3 of of IN cord-005646-xhx9pzhj 3905 4 normal normal JJ cord-005646-xhx9pzhj 3905 5 " " `` cord-005646-xhx9pzhj 3905 6 common common JJ cord-005646-xhx9pzhj 3905 7 " " '' cord-005646-xhx9pzhj 3905 8 VB vb NN cord-005646-xhx9pzhj 3905 9 systole systole NN cord-005646-xhx9pzhj 3905 10 : : : cord-005646-xhx9pzhj 3905 11 -begins -begin NNS cord-005646-xhx9pzhj 3905 12 with with IN cord-005646-xhx9pzhj 3905 13 blood blood NN cord-005646-xhx9pzhj 3905 14 ejection ejection NN cord-005646-xhx9pzhj 3905 15 from from IN cord-005646-xhx9pzhj 3905 16 VB VB NNP cord-005646-xhx9pzhj 3905 17 spongy spongy JJ cord-005646-xhx9pzhj 3905 18 chamber chamber NN cord-005646-xhx9pzhj 3905 19 into into IN cord-005646-xhx9pzhj 3905 20 the the DT cord-005646-xhx9pzhj 3905 21 " " `` cord-005646-xhx9pzhj 3905 22 atrial atrial JJ cord-005646-xhx9pzhj 3905 23 " " '' cord-005646-xhx9pzhj 3905 24 block block NN cord-005646-xhx9pzhj 3905 25 ; ; : cord-005646-xhx9pzhj 3905 26 -continues -continues : cord-005646-xhx9pzhj 3905 27 with with IN cord-005646-xhx9pzhj 3905 28 blood blood NN cord-005646-xhx9pzhj 3905 29 outflow outflow NN cord-005646-xhx9pzhj 3905 30 from from IN cord-005646-xhx9pzhj 3905 31 RV RV NNP cord-005646-xhx9pzhj 3905 32 and and CC cord-005646-xhx9pzhj 3905 33 LV LV NNP cord-005646-xhx9pzhj 3905 34 into into IN cord-005646-xhx9pzhj 3905 35 " " `` cord-005646-xhx9pzhj 3905 36 aorta aorta JJ cord-005646-xhx9pzhj 3905 37 - - HYPH cord-005646-xhx9pzhj 3905 38 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3905 39 " " '' cord-005646-xhx9pzhj 3905 40 block block NN cord-005646-xhx9pzhj 3905 41 wi~ wi~ NN cord-005646-xhx9pzhj 3905 42 venous venous JJ cord-005646-xhx9pzhj 3905 43 minimums minimum NNS cord-005646-xhx9pzhj 3905 44 -x -x : cord-005646-xhx9pzhj 3905 45 - - HYPH cord-005646-xhx9pzhj 3905 46 coiiapses coiiapse NNS cord-005646-xhx9pzhj 3906 1 -~btmation -~btmation NFP cord-005646-xhx9pzhj 3906 2 iu iu RB cord-005646-xhx9pzhj 3906 3 " " `` cord-005646-xhx9pzhj 3906 4 a a DT cord-005646-xhx9pzhj 3906 5 ~ ~ NFP cord-005646-xhx9pzhj 3906 6 riai riai NN cord-005646-xhx9pzhj 3906 7 " " '' cord-005646-xhx9pzhj 3906 8 block block NN cord-005646-xhx9pzhj 3906 9 ; ; : cord-005646-xhx9pzhj 3906 10 -completes -complete VBZ cord-005646-xhx9pzhj 3906 11 with with IN cord-005646-xhx9pzhj 3906 12 " " `` cord-005646-xhx9pzhj 3906 13 three three CD cord-005646-xhx9pzhj 3906 14 - - HYPH cord-005646-xhx9pzhj 3906 15 chambered chambered JJ cord-005646-xhx9pzhj 3906 16 " " '' cord-005646-xhx9pzhj 3906 17 VB VB NNP cord-005646-xhx9pzhj 3906 18 general general JJ cord-005646-xhx9pzhj 3906 19 emptying emptying NN cord-005646-xhx9pzhj 3906 20 . . . cord-005646-xhx9pzhj 3907 1 At at IN cord-005646-xhx9pzhj 3907 2 this this DT cord-005646-xhx9pzhj 3907 3 period period NN cord-005646-xhx9pzhj 3907 4 the the DT cord-005646-xhx9pzhj 3907 5 following follow VBG cord-005646-xhx9pzhj 3907 6 blood blood NN cord-005646-xhx9pzhj 3907 7 volumes volume NNS cord-005646-xhx9pzhj 3907 8 are be VBP cord-005646-xhx9pzhj 3907 9 transferring transfer VBG cord-005646-xhx9pzhj 3907 10 : : : cord-005646-xhx9pzhj 3907 11 -two -two ADD cord-005646-xhx9pzhj 3907 12 - - : cord-005646-xhx9pzhj 3907 13 from from IN cord-005646-xhx9pzhj 3907 14 RV RV NNP cord-005646-xhx9pzhj 3907 15 and and CC cord-005646-xhx9pzhj 3907 16 LV(their lv(their IN cord-005646-xhx9pzhj 3907 17 stroke stroke NN cord-005646-xhx9pzhj 3908 1 volumes)into"aor volumes)into"aor NNP cord-005646-xhx9pzhj 3909 1 ~o ~o VB cord-005646-xhx9pzhj 3909 2 - - : cord-005646-xhx9pzhj 3909 3 pulmonary"block pulmonary"block XX cord-005646-xhx9pzhj 3909 4 ; ; : cord-005646-xhx9pzhj 3909 5 -two -two ADD cord-005646-xhx9pzhj 3909 6 - - : cord-005646-xhx9pzhj 3909 7 from from IN cord-005646-xhx9pzhj 3909 8 " " `` cord-005646-xhx9pzhj 3909 9 spongy spongy JJ cord-005646-xhx9pzhj 3909 10 " " '' cord-005646-xhx9pzhj 3909 11 chamber chamber NN cord-005646-xhx9pzhj 3909 12 .into .into . cord-005646-xhx9pzhj 3909 13 " " `` cord-005646-xhx9pzhj 3909 14 atrial atrial JJ cord-005646-xhx9pzhj 3909 15 " " '' cord-005646-xhx9pzhj 3909 16 block block NN cord-005646-xhx9pzhj 3909 17 ; ; : cord-005646-xhx9pzhj 3909 18 -two -two ADD cord-005646-xhx9pzhj 3909 19 - - : cord-005646-xhx9pzhj 3909 20 from from IN cord-005646-xhx9pzhj 3909 21 systemic systemic JJ cord-005646-xhx9pzhj 3909 22 and and CC cord-005646-xhx9pzhj 3909 23 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3909 24 veins vein NNS cord-005646-xhx9pzhj 3909 25 into into IN cord-005646-xhx9pzhj 3909 26 " " `` cord-005646-xhx9pzhj 3909 27 atrial atrial JJ cord-005646-xhx9pzhj 3909 28 " " '' cord-005646-xhx9pzhj 3909 29 block block NN cord-005646-xhx9pzhj 3909 30 during during IN cord-005646-xhx9pzhj 3909 31 the the DT cord-005646-xhx9pzhj 3909 32 process process NN cord-005646-xhx9pzhj 3909 33 of of IN cord-005646-xhx9pzhj 3909 34 so so RB cord-005646-xhx9pzhj 3909 35 called call VBN cord-005646-xhx9pzhj 3909 36 " " `` cord-005646-xhx9pzhj 3909 37 systolic systolic JJ cord-005646-xhx9pzhj 3909 38 " " '' cord-005646-xhx9pzhj 3909 39 membrane membrane NN cord-005646-xhx9pzhj 3909 40 suction suction NN cord-005646-xhx9pzhj 3909 41 ( ( -LRB- cord-005646-xhx9pzhj 3909 42 at at IN cord-005646-xhx9pzhj 3909 43 pulling pull VBG cord-005646-xhx9pzhj 3909 44 atrio atrio JJ cord-005646-xhx9pzhj 3909 45 - - HYPH cord-005646-xhx9pzhj 3909 46 ventricular ventricular JJ cord-005646-xhx9pzhj 3909 47 valves valve NNS cord-005646-xhx9pzhj 3909 48 into into IN cord-005646-xhx9pzhj 3909 49 RV RV NNP cord-005646-xhx9pzhj 3909 50 and and CC cord-005646-xhx9pzhj 3909 51 LV LV NNP cord-005646-xhx9pzhj 3909 52 chambers chamber NNS cord-005646-xhx9pzhj 3909 53 as as IN cord-005646-xhx9pzhj 3909 54 blood blood NN cord-005646-xhx9pzhj 3909 55 ejects eject VBZ cord-005646-xhx9pzhj 3909 56 out out IN cord-005646-xhx9pzhj 3909 57 of of IN cord-005646-xhx9pzhj 3909 58 them -PRON- PRP cord-005646-xhx9pzhj 3909 59 ) ) -RRB- cord-005646-xhx9pzhj 3909 60 . . . cord-005646-xhx9pzhj 3910 1 It -PRON- PRP cord-005646-xhx9pzhj 3910 2 appears appear VBZ cord-005646-xhx9pzhj 3910 3 to to TO cord-005646-xhx9pzhj 3910 4 be be VB cord-005646-xhx9pzhj 3910 5 the the DT cord-005646-xhx9pzhj 3910 6 regulation regulation NN cord-005646-xhx9pzhj 3910 7 of of IN cord-005646-xhx9pzhj 3910 8 blood blood NN cord-005646-xhx9pzhj 3910 9 inflow inflow NN cord-005646-xhx9pzhj 3910 10 to to IN cord-005646-xhx9pzhj 3910 11 " " `` cord-005646-xhx9pzhj 3910 12 atrial atrial JJ cord-005646-xhx9pzhj 3910 13 " " '' cord-005646-xhx9pzhj 3910 14 block block NN cord-005646-xhx9pzhj 3910 15 by by IN cord-005646-xhx9pzhj 3910 16 blond blond JJ cord-005646-xhx9pzhj 3910 17 outflow outflow NN cord-005646-xhx9pzhj 3910 18 from from IN cord-005646-xhx9pzhj 3910 19 " " `` cord-005646-xhx9pzhj 3910 20 three three CD cord-005646-xhx9pzhj 3910 21 - - HYPH cord-005646-xhx9pzhj 3910 22 chambered chambered JJ cord-005646-xhx9pzhj 3910 23 " " '' cord-005646-xhx9pzhj 3910 24 VB vb NN cord-005646-xhx9pzhj 3910 25 into into IN cord-005646-xhx9pzhj 3910 26 " " `` cord-005646-xhx9pzhj 3910 27 aorto aorto JJ cord-005646-xhx9pzhj 3910 28 - - HYPH cord-005646-xhx9pzhj 3910 29 pulmonary pulmonary JJ cord-005646-xhx9pzhj 3910 30 " " '' cord-005646-xhx9pzhj 3910 31 block block NN cord-005646-xhx9pzhj 3910 32 . . . cord-005646-xhx9pzhj 3911 1 Objective objective NN cord-005646-xhx9pzhj 3911 2 : : : cord-005646-xhx9pzhj 3912 1 To to TO cord-005646-xhx9pzhj 3912 2 evaluate evaluate VB cord-005646-xhx9pzhj 3912 3 the the DT cord-005646-xhx9pzhj 3912 4 efficacy efficacy NN cord-005646-xhx9pzhj 3912 5 and and CC cord-005646-xhx9pzhj 3912 6 complications complication NNS cord-005646-xhx9pzhj 3912 7 of of IN cord-005646-xhx9pzhj 3912 8 Transpyloric Transpyloric NNP cord-005646-xhx9pzhj 3912 9 Enteral Enteral NNP cord-005646-xhx9pzhj 3912 10 Nutrition(TEN Nutrition(TEN NNP cord-005646-xhx9pzhj 3912 11 ) ) -RRB- cord-005646-xhx9pzhj 3912 12 in in IN cord-005646-xhx9pzhj 3912 13 critically critically RB cord-005646-xhx9pzhj 3912 14 ill ill JJ cord-005646-xhx9pzhj 3912 15 children child NNS cord-005646-xhx9pzhj 3912 16 Patients patient NNS cord-005646-xhx9pzhj 3912 17 and and CC cord-005646-xhx9pzhj 3912 18 methods~ methods~ JJ cord-005646-xhx9pzhj 3913 1 From from IN cord-005646-xhx9pzhj 3913 2 June June NNP cord-005646-xhx9pzhj 3913 3 1994 1994 CD cord-005646-xhx9pzhj 3913 4 to to IN cord-005646-xhx9pzhj 3913 5 January January NNP cord-005646-xhx9pzhj 3913 6 1996 1996 CD cord-005646-xhx9pzhj 3913 7 23 23 CD cord-005646-xhx9pzhj 3913 8 children child NNS cord-005646-xhx9pzhj 3913 9 ( ( -LRB- cord-005646-xhx9pzhj 3913 10 I0 i0 NN cord-005646-xhx9pzhj 3913 11 boys boy NNS cord-005646-xhx9pzhj 3913 12 and and CC cord-005646-xhx9pzhj 3913 13 13 13 CD cord-005646-xhx9pzhj 3913 14 girls girl NNS cord-005646-xhx9pzhj 3913 15 ) ) -RRB- cord-005646-xhx9pzhj 3913 16 , , , cord-005646-xhx9pzhj 3913 17 aged age VBN cord-005646-xhx9pzhj 3913 18 from from IN cord-005646-xhx9pzhj 3913 19 5 5 CD cord-005646-xhx9pzhj 3913 20 days day NNS cord-005646-xhx9pzhj 3913 21 to to IN cord-005646-xhx9pzhj 3913 22 11 11 CD cord-005646-xhx9pzhj 3913 23 years year NNS cord-005646-xhx9pzhj 3914 1 ( ( -LRB- cord-005646-xhx9pzhj 3914 2 mean mean VB cord-005646-xhx9pzhj 3915 1 l.8 l.8 NNP cord-005646-xhx9pzhj 3915 2 ± ± NNP cord-005646-xhx9pzhj 3915 3 3.4years 3.4year NNS cord-005646-xhx9pzhj 3915 4 ) ) -RRB- cord-005646-xhx9pzhj 3915 5 were be VBD cord-005646-xhx9pzhj 3915 6 treated treat VBN cord-005646-xhx9pzhj 3915 7 with with IN cord-005646-xhx9pzhj 3915 8 TEN ten CD cord-005646-xhx9pzhj 3915 9 . . . cord-005646-xhx9pzhj 3916 1 18 18 CD cord-005646-xhx9pzhj 3916 2 patients patient NNS cord-005646-xhx9pzhj 3916 3 were be VBD cord-005646-xhx9pzhj 3916 4 included include VBN cord-005646-xhx9pzhj 3916 5 after after IN cord-005646-xhx9pzhj 3916 6 cardiac cardiac JJ cord-005646-xhx9pzhj 3916 7 surgery surgery NN cord-005646-xhx9pzhj 3916 8 , , , cord-005646-xhx9pzhj 3916 9 3 3 CD cord-005646-xhx9pzhj 3916 10 with with IN cord-005646-xhx9pzhj 3916 11 acute acute JJ cord-005646-xhx9pzhj 3916 12 respiratory respiratory JJ cord-005646-xhx9pzhj 3916 13 failure failure NN cord-005646-xhx9pzhj 3916 14 , , , cord-005646-xhx9pzhj 3916 15 and and CC cord-005646-xhx9pzhj 3916 16 2 2 CD cord-005646-xhx9pzhj 3916 17 after after IN cord-005646-xhx9pzhj 3916 18 cerebral cerebral JJ cord-005646-xhx9pzhj 3916 19 surgery surgery NN cord-005646-xhx9pzhj 3916 20 . . . cord-005646-xhx9pzhj 3917 1 The the DT cord-005646-xhx9pzhj 3917 2 indication indication NN cord-005646-xhx9pzhj 3917 3 of of IN cord-005646-xhx9pzhj 3917 4 TEN TEN NNP cord-005646-xhx9pzhj 3917 5 was be VBD cord-005646-xhx9pzhj 3917 6 mechanical mechanical JJ cord-005646-xhx9pzhj 3917 7 ventilation ventilation NN cord-005646-xhx9pzhj 3917 8 in in IN cord-005646-xhx9pzhj 3917 9 22 22 CD cord-005646-xhx9pzhj 3917 10 patients patient NNS cord-005646-xhx9pzhj 3917 11 and and CC cord-005646-xhx9pzhj 3917 12 failure failure NN cord-005646-xhx9pzhj 3917 13 of of IN cord-005646-xhx9pzhj 3917 14 nasogastric nasogastric NN cord-005646-xhx9pzhj 3917 15 nutrition nutrition NN cord-005646-xhx9pzhj 3917 16 in in IN cord-005646-xhx9pzhj 3917 17 1 1 CD cord-005646-xhx9pzhj 3917 18 patient.19 patient.19 NNP cord-005646-xhx9pzhj 3917 19 children child NNS cord-005646-xhx9pzhj 3917 20 ( ( -LRB- cord-005646-xhx9pzhj 3917 21 82 82 CD cord-005646-xhx9pzhj 3917 22 % % NN cord-005646-xhx9pzhj 3917 23 ) ) -RRB- cord-005646-xhx9pzhj 3917 24 had have VBD cord-005646-xhx9pzhj 3917 25 previously previously RB cord-005646-xhx9pzhj 3917 26 received receive VBN cord-005646-xhx9pzhj 3917 27 parenteral parenteral JJ cord-005646-xhx9pzhj 3917 28 nutrition nutrition NN cord-005646-xhx9pzhj 3917 29 . . . cord-005646-xhx9pzhj 3918 1 8 8 CD cord-005646-xhx9pzhj 3918 2 and and CC cord-005646-xhx9pzhj 3918 3 I0 I0 NNP cord-005646-xhx9pzhj 3918 4 FG FG NNP cord-005646-xhx9pzhj 3918 5 enteral enteral NN cord-005646-xhx9pzhj 3918 6 tubes tube NNS cord-005646-xhx9pzhj 3918 7 was be VBD cord-005646-xhx9pzhj 3918 8 inserted insert VBN cord-005646-xhx9pzhj 3918 9 into into IN cord-005646-xhx9pzhj 3918 10 duodenus duodenus NNP cord-005646-xhx9pzhj 3918 11 through through IN cord-005646-xhx9pzhj 3918 12 nasogastric nasogastric NN cord-005646-xhx9pzhj 3918 13 intubation intubation NN cord-005646-xhx9pzhj 3918 14 en en IN cord-005646-xhx9pzhj 3918 15 21 21 CD cord-005646-xhx9pzhj 3918 16 patients patient NNS cord-005646-xhx9pzhj 3918 17 and and CC cord-005646-xhx9pzhj 3918 18 by by IN cord-005646-xhx9pzhj 3918 19 endoscopy endoscopy NN cord-005646-xhx9pzhj 3918 20 in in IN cord-005646-xhx9pzhj 3918 21 2 2 CD cord-005646-xhx9pzhj 3918 22 patients patient NNS cord-005646-xhx9pzhj 3918 23 . . . cord-005646-xhx9pzhj 3919 1 Rx Rx NNP cord-005646-xhx9pzhj 3919 2 and and CC cord-005646-xhx9pzhj 3919 3 pH pH NNP cord-005646-xhx9pzhj 3919 4 determination determination NN cord-005646-xhx9pzhj 3919 5 were be VBD cord-005646-xhx9pzhj 3919 6 used use VBN cord-005646-xhx9pzhj 3919 7 as as IN cord-005646-xhx9pzhj 3919 8 methods method NNS cord-005646-xhx9pzhj 3919 9 to to TO cord-005646-xhx9pzhj 3919 10 control control VB cord-005646-xhx9pzhj 3919 11 tube tube NN cord-005646-xhx9pzhj 3919 12 situation situation NN cord-005646-xhx9pzhj 3919 13 . . . cord-005646-xhx9pzhj 3920 1 18 18 CD cord-005646-xhx9pzhj 3920 2 children child NNS cord-005646-xhx9pzhj 3920 3 received receive VBD cord-005646-xhx9pzhj 3920 4 adapted adapt VBN cord-005646-xhx9pzhj 3920 5 formula formula NN cord-005646-xhx9pzhj 3920 6 , , , cord-005646-xhx9pzhj 3920 7 7 7 CD cord-005646-xhx9pzhj 3920 8 caseine caseine NNP cord-005646-xhx9pzhj 3920 9 hidrolisate hidrolisate NNP cord-005646-xhx9pzhj 3920 10 , , , cord-005646-xhx9pzhj 3920 11 and and CC cord-005646-xhx9pzhj 3920 12 3 3 CD cord-005646-xhx9pzhj 3920 13 enteral enteral JJ cord-005646-xhx9pzhj 3920 14 formulas formula NNS cord-005646-xhx9pzhj 3920 15 . . . cord-005646-xhx9pzhj 3921 1 ( ( -LRB- cord-005646-xhx9pzhj 3921 2 In in IN cord-005646-xhx9pzhj 3921 3 5 5 CD cord-005646-xhx9pzhj 3921 4 patients patient NNS cord-005646-xhx9pzhj 3921 5 the the DT cord-005646-xhx9pzhj 3921 6 nutrition nutrition NN cord-005646-xhx9pzhj 3921 7 formula formula NN cord-005646-xhx9pzhj 3921 8 was be VBD cord-005646-xhx9pzhj 3921 9 changed change VBN cord-005646-xhx9pzhj 3921 10 during during IN cord-005646-xhx9pzhj 3921 11 TEN ten CD cord-005646-xhx9pzhj 3921 12 ) ) -RRB- cord-005646-xhx9pzhj 3921 13 . . . cord-005646-xhx9pzhj 3922 1 22 22 CD cord-005646-xhx9pzhj 3922 2 patients patient NNS cord-005646-xhx9pzhj 3922 3 were be VBD cord-005646-xhx9pzhj 3922 4 supported support VBN cord-005646-xhx9pzhj 3922 5 with with IN cord-005646-xhx9pzhj 3922 6 mechanical mechanical JJ cord-005646-xhx9pzhj 3922 7 ventilation ventilation NN cord-005646-xhx9pzhj 3922 8 during during IN cord-005646-xhx9pzhj 3922 9 TEN ten CD cord-005646-xhx9pzhj 3922 10 , , , cord-005646-xhx9pzhj 3922 11 17 17 CD cord-005646-xhx9pzhj 3922 12 received receive VBD cord-005646-xhx9pzhj 3922 13 midazolamperfussion(range midazolamperfussion(range CD cord-005646-xhx9pzhj 3922 14 2 2 CD cord-005646-xhx9pzhj 3922 15 to to IN cord-005646-xhx9pzhj 3922 16 15 15 CD cord-005646-xhx9pzhj 3922 17 mcg mcg NN cord-005646-xhx9pzhj 3922 18 / / SYM cord-005646-xhx9pzhj 3922 19 kg kg NNP cord-005646-xhx9pzhj 3922 20 / / SYM cord-005646-xhx9pzhj 3922 21 min min NNP cord-005646-xhx9pzhj 3922 22 ) ) -RRB- cord-005646-xhx9pzhj 3922 23 , , , cord-005646-xhx9pzhj 3922 24 15 15 CD cord-005646-xhx9pzhj 3922 25 fentanyl fentanyl NN cord-005646-xhx9pzhj 3922 26 ( ( -LRB- cord-005646-xhx9pzhj 3922 27 i i NN cord-005646-xhx9pzhj 3922 28 -12.5 -12.5 . cord-005646-xhx9pzhj 3923 1 mcg mcg NNP cord-005646-xhx9pzhj 3923 2 / / SYM cord-005646-xhx9pzhj 3923 3 kg kg NNP cord-005646-xhx9pzhj 3923 4 / / SYM cord-005646-xhx9pzhj 3923 5 h h NNP cord-005646-xhx9pzhj 3923 6 ) ) -RRB- cord-005646-xhx9pzhj 3923 7 , , , cord-005646-xhx9pzhj 3923 8 and and CC cord-005646-xhx9pzhj 3923 9 6 6 CD cord-005646-xhx9pzhj 3923 10 vecuronium vecuronium NN cord-005646-xhx9pzhj 3923 11 ( ( -LRB- cord-005646-xhx9pzhj 3923 12 0.1 0.1 CD cord-005646-xhx9pzhj 3923 13 -0.3 -0.3 NFP cord-005646-xhx9pzhj 3923 14 mg mg NNP cord-005646-xhx9pzhj 3923 15 / / SYM cord-005646-xhx9pzhj 3923 16 kg kg NNP cord-005646-xhx9pzhj 3923 17 / / SYM cord-005646-xhx9pzhj 3923 18 h h NN cord-005646-xhx9pzhj 3923 19 ) ) -RRB- cord-005646-xhx9pzhj 3923 20 . . . cord-005646-xhx9pzhj 3924 1 Resulte Resulte NNP cord-005646-xhx9pzhj 3924 2 : : : cord-005646-xhx9pzhj 3924 3 TEN ten CD cord-005646-xhx9pzhj 3924 4 was be VBD cord-005646-xhx9pzhj 3924 5 used use VBN cord-005646-xhx9pzhj 3924 6 during during IN cord-005646-xhx9pzhj 3924 7 3 3 CD cord-005646-xhx9pzhj 3924 8 to to TO cord-005646-xhx9pzhj 3924 9 73 73 CD cord-005646-xhx9pzhj 3924 10 days day NNS cord-005646-xhx9pzhj 3924 11 ( ( -LRB- cord-005646-xhx9pzhj 3924 12 mean mean VB cord-005646-xhx9pzhj 3924 13 18.3 18.3 CD cord-005646-xhx9pzhj 3924 14 ± ± CD cord-005646-xhx9pzhj 3924 15 19.3 19.3 CD cord-005646-xhx9pzhj 3924 16 days day NNS cord-005646-xhx9pzhj 3924 17 ) ) -RRB- cord-005646-xhx9pzhj 3924 18 . . . cord-005646-xhx9pzhj 3925 1 Mean mean JJ cord-005646-xhx9pzhj 3925 2 maximmnvolume maximmnvolume NNP cord-005646-xhx9pzhj 3925 3 ad ad NN cord-005646-xhx9pzhj 3926 1 ~iniateredwas ~iniateredwas NNP cord-005646-xhx9pzhj 3926 2 132 132 CD cord-005646-xhx9pzhj 3926 3 ± ± CD cord-005646-xhx9pzhj 3926 4 47 47 CD cord-005646-xhx9pzhj 3927 1 ml ml NNP cord-005646-xhx9pzhj 3927 2 / / SYM cord-005646-xhx9pzhj 3927 3 kg kg NNP cord-005646-xhx9pzhj 3927 4 / / SYM cord-005646-xhx9pzhj 3927 5 day day NN cord-005646-xhx9pzhj 3927 6 ( ( -LRB- cord-005646-xhx9pzhj 3927 7 range range NN cord-005646-xhx9pzhj 3927 8 34 34 CD cord-005646-xhx9pzhj 3927 9 208 208 CD cord-005646-xhx9pzhj 3927 10 ) ) -RRB- cord-005646-xhx9pzhj 3927 11 .Patients .Patients . cord-005646-xhx9pzhj 3928 1 with with IN cord-005646-xhx9pzhj 3928 2 midazolam midazolam NNP cord-005646-xhx9pzhj 3928 3 , , , cord-005646-xhx9pzhj 3928 4 fentanyl fentanyl NN cord-005646-xhx9pzhj 3928 5 and and CC cord-005646-xhx9pzhj 3928 6 vecuronitml vecuronitml NN cord-005646-xhx9pzhj 3928 7 tolerated tolerate VBD cord-005646-xhx9pzhj 3928 8 TEN ten CD cord-005646-xhx9pzhj 3928 9 similar similar JJ cord-005646-xhx9pzhj 3928 10 than than IN cord-005646-xhx9pzhj 3928 11 children child NNS cord-005646-xhx9pzhj 3928 12 without without IN cord-005646-xhx9pzhj 3928 13 sedatives sedative NNS cord-005646-xhx9pzhj 3928 14 . . . cord-005646-xhx9pzhj 3929 1 Complications complication NNS cord-005646-xhx9pzhj 3929 2 were be VBD cord-005646-xhx9pzhj 3929 3 diarrhoea diarrhoea NN cord-005646-xhx9pzhj 3929 4 1 1 CD cord-005646-xhx9pzhj 3929 5 patient patient NN cord-005646-xhx9pzhj 3929 6 , , , cord-005646-xhx9pzhj 3929 7 abdominal abdominal JJ cord-005646-xhx9pzhj 3929 8 distension distension NN cord-005646-xhx9pzhj 3929 9 and/or and/or CC cord-005646-xhx9pzhj 3929 10 important important JJ cord-005646-xhx9pzhj 3929 11 gastric gastric JJ cord-005646-xhx9pzhj 3929 12 fed fed JJ cord-005646-xhx9pzhj 3929 13 residuals residual NNS cord-005646-xhx9pzhj 3929 14 2 2 CD cord-005646-xhx9pzhj 3929 15 patients patient NNS cord-005646-xhx9pzhj 3929 16 . . . cord-005646-xhx9pzhj 3930 1 Pulmonary pulmonary JJ cord-005646-xhx9pzhj 3930 2 aspiration aspiration NN cord-005646-xhx9pzhj 3930 3 or or CC cord-005646-xhx9pzhj 3930 4 respiratory respiratory JJ cord-005646-xhx9pzhj 3930 5 complications complication NNS cord-005646-xhx9pzhj 3930 6 were be VBD cord-005646-xhx9pzhj 3930 7 no no DT cord-005646-xhx9pzhj 3930 8 registered register VBN cord-005646-xhx9pzhj 3930 9 . . . cord-005646-xhx9pzhj 3931 1 TEN TEN NNP cord-005646-xhx9pzhj 3931 2 was be VBD cord-005646-xhx9pzhj 3931 3 ended end VBN cord-005646-xhx9pzhj 3931 4 in in IN cord-005646-xhx9pzhj 3931 5 one one CD cord-005646-xhx9pzhj 3931 6 patient patient NN cord-005646-xhx9pzhj 3931 7 due due IN cord-005646-xhx9pzhj 3931 8 to to IN cord-005646-xhx9pzhj 3931 9 diarrhoea diarrhoea NN cord-005646-xhx9pzhj 3931 10 , , , cord-005646-xhx9pzhj 3931 11 in in IN cord-005646-xhx9pzhj 3931 12 18 18 CD cord-005646-xhx9pzhj 3931 13 due due JJ cord-005646-xhx9pzhj 3931 14 to to TO cord-005646-xhx9pzhj 3931 15 change change VB cord-005646-xhx9pzhj 3931 16 to to IN cord-005646-xhx9pzhj 3931 17 oral oral JJ cord-005646-xhx9pzhj 3931 18 or or CC cord-005646-xhx9pzhj 3931 19 nasogastric nasogastric NN cord-005646-xhx9pzhj 3931 20 nutrition nutrition NN cord-005646-xhx9pzhj 3931 21 , , , cord-005646-xhx9pzhj 3931 22 3 3 CD cord-005646-xhx9pzhj 3931 23 children child NNS cord-005646-xhx9pzhj 3931 24 continue continue VBP cord-005646-xhx9pzhj 3931 25 yet yet RB cord-005646-xhx9pzhj 3931 26 with with IN cord-005646-xhx9pzhj 3931 27 TEN ten CD cord-005646-xhx9pzhj 3931 28 and and CC cord-005646-xhx9pzhj 3931 29 1 1 CD cord-005646-xhx9pzhj 3931 30 was be VBD cord-005646-xhx9pzhj 3931 31 discharged discharge VBN cord-005646-xhx9pzhj 3931 32 of of IN cord-005646-xhx9pzhj 3931 33 PICUwith PICUwith NNP cord-005646-xhx9pzhj 3931 34 TEN ten CD cord-005646-xhx9pzhj 3931 35 . . . cord-005646-xhx9pzhj 3932 1 Conolusion conolusion NN cord-005646-xhx9pzhj 3932 2 : : : cord-005646-xhx9pzhj 3933 1 TEN ten CD cord-005646-xhx9pzhj 3933 2 is be VBZ cord-005646-xhx9pzhj 3933 3 an an DT cord-005646-xhx9pzhj 3933 4 useful useful JJ cord-005646-xhx9pzhj 3933 5 method method NN cord-005646-xhx9pzhj 3933 6 of of IN cord-005646-xhx9pzhj 3933 7 nutritional nutritional JJ cord-005646-xhx9pzhj 3933 8 support support NN cord-005646-xhx9pzhj 3933 9 in in IN cord-005646-xhx9pzhj 3933 10 critically critically RB cord-005646-xhx9pzhj 3933 11 Ill ill JJ cord-005646-xhx9pzhj 3933 12 children child NNS cord-005646-xhx9pzhj 3933 13 with with IN cord-005646-xhx9pzhj 3933 14 mechanical mechanical JJ cord-005646-xhx9pzhj 3933 15 ventilation ventilation NN cord-005646-xhx9pzhj 3933 16 and/or and/or CC cord-005646-xhx9pzhj 3933 17 nasogastric nasogastric NN cord-005646-xhx9pzhj 3933 18 intolerance intolerance NN cord-005646-xhx9pzhj 3933 19 . . . cord-005646-xhx9pzhj 3934 1 Introduction introduction NN cord-005646-xhx9pzhj 3934 2 : : : cord-005646-xhx9pzhj 3935 1 the the DT cord-005646-xhx9pzhj 3935 2 enteral enteral JJ cord-005646-xhx9pzhj 3935 3 nutritional nutritional JJ cord-005646-xhx9pzhj 3935 4 support support NN cord-005646-xhx9pzhj 3935 5 of of IN cord-005646-xhx9pzhj 3935 6 the the DT cord-005646-xhx9pzhj 3935 7 critically critically RB cord-005646-xhx9pzhj 3935 8 ill ill JJ cord-005646-xhx9pzhj 3935 9 child child NN cord-005646-xhx9pzhj 3935 10 may may MD cord-005646-xhx9pzhj 3935 11 reduce reduce VB cord-005646-xhx9pzhj 3935 12 the the DT cord-005646-xhx9pzhj 3935 13 morbidity morbidity NN cord-005646-xhx9pzhj 3935 14 and and CC cord-005646-xhx9pzhj 3935 15 mortality mortality NN cord-005646-xhx9pzhj 3935 16 by by IN cord-005646-xhx9pzhj 3935 17 attenuating attenuate VBG cord-005646-xhx9pzhj 3935 18 , , , cord-005646-xhx9pzhj 3935 19 the the DT cord-005646-xhx9pzhj 3935 20 hypermetabolic hypermetabolic NN cord-005646-xhx9pzhj 3935 21 and and CC cord-005646-xhx9pzhj 3935 22 catabolic catabolic JJ cord-005646-xhx9pzhj 3935 23 response response NN cord-005646-xhx9pzhj 3935 24 , , , cord-005646-xhx9pzhj 3935 25 decreasing decrease VBG cord-005646-xhx9pzhj 3935 26 the the DT cord-005646-xhx9pzhj 3935 27 gut gut NN cord-005646-xhx9pzhj 3935 28 translocation translocation NN cord-005646-xhx9pzhj 3935 29 and and CC cord-005646-xhx9pzhj 3935 30 the the DT cord-005646-xhx9pzhj 3935 31 septic septic JJ cord-005646-xhx9pzhj 3935 32 complications complication NNS cord-005646-xhx9pzhj 3935 33 , , , cord-005646-xhx9pzhj 3935 34 improving improve VBG cord-005646-xhx9pzhj 3935 35 the the DT cord-005646-xhx9pzhj 3935 36 bowel bowel NN cord-005646-xhx9pzhj 3935 37 mucosa mucosa JJ cord-005646-xhx9pzhj 3935 38 integrity integrity NN cord-005646-xhx9pzhj 3935 39 and and CC cord-005646-xhx9pzhj 3935 40 the the DT cord-005646-xhx9pzhj 3935 41 wound wound NN cord-005646-xhx9pzhj 3935 42 healing healing NN cord-005646-xhx9pzhj 3935 43 . . . cord-005646-xhx9pzhj 3936 1 The the DT cord-005646-xhx9pzhj 3936 2 aim aim NN cord-005646-xhx9pzhj 3936 3 of of IN cord-005646-xhx9pzhj 3936 4 this this DT cord-005646-xhx9pzhj 3936 5 study study NN cord-005646-xhx9pzhj 3936 6 was be VBD cord-005646-xhx9pzhj 3936 7 to to TO cord-005646-xhx9pzhj 3936 8 show show VB cord-005646-xhx9pzhj 3936 9 the the DT cord-005646-xhx9pzhj 3936 10 safety safety NN cord-005646-xhx9pzhj 3936 11 and and CC cord-005646-xhx9pzhj 3936 12 tolerance tolerance NN cord-005646-xhx9pzhj 3936 13 of of IN cord-005646-xhx9pzhj 3936 14 EN EN NNP cord-005646-xhx9pzhj 3936 15 . . . cord-005646-xhx9pzhj 3937 1 Methods method NNS cord-005646-xhx9pzhj 3937 2 : : : cord-005646-xhx9pzhj 3937 3 we -PRON- PRP cord-005646-xhx9pzhj 3937 4 enrolled enrol VBD cord-005646-xhx9pzhj 3937 5 36 36 CD cord-005646-xhx9pzhj 3937 6 consecutive consecutive JJ cord-005646-xhx9pzhj 3937 7 patients patient NNS cord-005646-xhx9pzhj 3937 8 admitted admit VBN cord-005646-xhx9pzhj 3937 9 to to IN cord-005646-xhx9pzhj 3937 10 our -PRON- PRP$ cord-005646-xhx9pzhj 3937 11 Unit Unit NNP cord-005646-xhx9pzhj 3937 12 from from IN cord-005646-xhx9pzhj 3937 13 May May NNP cord-005646-xhx9pzhj 3937 14 to to IN cord-005646-xhx9pzhj 3937 15 December December NNP cord-005646-xhx9pzhj 3937 16 1995 1995 CD cord-005646-xhx9pzhj 3937 17 , , , cord-005646-xhx9pzhj 3937 18 mean mean VBP cord-005646-xhx9pzhj 3937 19 age age NN cord-005646-xhx9pzhj 3937 20 3.4 3.4 CD cord-005646-xhx9pzhj 3937 21 years year NNS cord-005646-xhx9pzhj 3937 22 ( ( -LRB- cord-005646-xhx9pzhj 3937 23 range range VBP cord-005646-xhx9pzhj 3937 24 Imonth Imonth NNP cord-005646-xhx9pzhj 3937 25 to to IN cord-005646-xhx9pzhj 3937 26 I7 I7 NNP cord-005646-xhx9pzhj 3937 27 years year NNS cord-005646-xhx9pzhj 3937 28 ) ) -RRB- cord-005646-xhx9pzhj 3937 29 . . . cord-005646-xhx9pzhj 3938 1 The the DT cord-005646-xhx9pzhj 3938 2 PRISM prism NN cord-005646-xhx9pzhj 3938 3 , , , cord-005646-xhx9pzhj 3938 4 mechanical mechanical JJ cord-005646-xhx9pzhj 3938 5 ventilation ventilation NN cord-005646-xhx9pzhj 3938 6 , , , cord-005646-xhx9pzhj 3938 7 inotropic inotropic NNP cord-005646-xhx9pzhj 3938 8 use use VBP cord-005646-xhx9pzhj 3938 9 , , , cord-005646-xhx9pzhj 3938 10 opiates opiate NNS cord-005646-xhx9pzhj 3938 11 and and CC cord-005646-xhx9pzhj 3938 12 other other JJ cord-005646-xhx9pzhj 3938 13 drugs drug NNS cord-005646-xhx9pzhj 3938 14 were be VBD cord-005646-xhx9pzhj 3938 15 recorded record VBN cord-005646-xhx9pzhj 3938 16 . . . cord-005646-xhx9pzhj 3939 1 The the DT cord-005646-xhx9pzhj 3939 2 EN EN NNP cord-005646-xhx9pzhj 3939 3 was be VBD cord-005646-xhx9pzhj 3939 4 delivered deliver VBN cord-005646-xhx9pzhj 3939 5 by by IN cord-005646-xhx9pzhj 3939 6 continuous continuous JJ cord-005646-xhx9pzhj 3939 7 infusion infusion NN cord-005646-xhx9pzhj 3939 8 across across IN cord-005646-xhx9pzhj 3939 9 a a DT cord-005646-xhx9pzhj 3939 10 polyuretane polyuretane NN cord-005646-xhx9pzhj 3939 11 tube tube NN cord-005646-xhx9pzhj 3939 12 . . . cord-005646-xhx9pzhj 3940 1 We -PRON- PRP cord-005646-xhx9pzhj 3940 2 kept keep VBD cord-005646-xhx9pzhj 3940 3 the the DT cord-005646-xhx9pzhj 3940 4 patients patient NNS cord-005646-xhx9pzhj 3940 5 head head VB cord-005646-xhx9pzhj 3940 6 elevated elevate VBN cord-005646-xhx9pzhj 3940 7 30 30 CD cord-005646-xhx9pzhj 3940 8 ° ° NNS cord-005646-xhx9pzhj 3940 9 , , , cord-005646-xhx9pzhj 3940 10 and and CC cord-005646-xhx9pzhj 3940 11 we -PRON- PRP cord-005646-xhx9pzhj 3940 12 used use VBD cord-005646-xhx9pzhj 3940 13 cisapride cisapride NNP cord-005646-xhx9pzhj 3940 14 routinely routinely RB cord-005646-xhx9pzhj 3940 15 . . . cord-005646-xhx9pzhj 3941 1 The the DT cord-005646-xhx9pzhj 3941 2 gap gap NN cord-005646-xhx9pzhj 3941 3 betweeen betweeen IN cord-005646-xhx9pzhj 3941 4 admission admission NN cord-005646-xhx9pzhj 3941 5 and and CC cord-005646-xhx9pzhj 3941 6 the the DT cord-005646-xhx9pzhj 3941 7 EN EN NNP cord-005646-xhx9pzhj 3941 8 beginning beginning NN cord-005646-xhx9pzhj 3941 9 , , , cord-005646-xhx9pzhj 3941 10 average average JJ cord-005646-xhx9pzhj 3941 11 time time NN cord-005646-xhx9pzhj 3941 12 to to TO cord-005646-xhx9pzhj 3941 13 meet meet VB cord-005646-xhx9pzhj 3941 14 the the DT cord-005646-xhx9pzhj 3941 15 nutritional nutritional JJ cord-005646-xhx9pzhj 3941 16 objective objective NN cord-005646-xhx9pzhj 3941 17 , , , cord-005646-xhx9pzhj 3941 18 EN EN NNP cord-005646-xhx9pzhj 3941 19 duration duration NN cord-005646-xhx9pzhj 3941 20 , , , cord-005646-xhx9pzhj 3941 21 selected select VBN cord-005646-xhx9pzhj 3941 22 formula formula NN cord-005646-xhx9pzhj 3941 23 , , , cord-005646-xhx9pzhj 3941 24 patients patient NNS cord-005646-xhx9pzhj 3941 25 outcome outcome NN cord-005646-xhx9pzhj 3941 26 and and CC cord-005646-xhx9pzhj 3941 27 complications complication NNS cord-005646-xhx9pzhj 3941 28 were be VBD cord-005646-xhx9pzhj 3941 29 recorded record VBN cord-005646-xhx9pzhj 3941 30 . . . cord-005646-xhx9pzhj 3942 1 Results result NNS cord-005646-xhx9pzhj 3942 2 : : : cord-005646-xhx9pzhj 3943 1 PRISM prism NN cord-005646-xhx9pzhj 3943 2 groups group NNS cord-005646-xhx9pzhj 3943 3 were be VBD cord-005646-xhx9pzhj 3943 4 0 0 CD cord-005646-xhx9pzhj 3943 5 - - SYM cord-005646-xhx9pzhj 3943 6 1=0 1=0 CD cord-005646-xhx9pzhj 3943 7 patients patient NNS cord-005646-xhx9pzhj 3943 8 ; ; : cord-005646-xhx9pzhj 3943 9 1 1 CD cord-005646-xhx9pzhj 3943 10 - - HYPH cord-005646-xhx9pzhj 3943 11 5=1 5=1 CD cord-005646-xhx9pzhj 3943 12 ; ; : cord-005646-xhx9pzhj 3943 13 5 5 CD cord-005646-xhx9pzhj 3943 14 - - HYPH cord-005646-xhx9pzhj 3943 15 10=13 10=13 CD cord-005646-xhx9pzhj 3943 16 ; ; : cord-005646-xhx9pzhj 3943 17 10 10 CD cord-005646-xhx9pzhj 3943 18 - - SYM cord-005646-xhx9pzhj 3943 19 15=7 15=7 CD cord-005646-xhx9pzhj 3943 20 ; ; : cord-005646-xhx9pzhj 3943 21 15 15 CD cord-005646-xhx9pzhj 3943 22 - - HYPH cord-005646-xhx9pzhj 3943 23 30=12 30=12 NN cord-005646-xhx9pzhj 3943 24 . . . cord-005646-xhx9pzhj 3944 1 Two two CD cord-005646-xhx9pzhj 3944 2 patients patient NNS cord-005646-xhx9pzhj 3944 3 with with IN cord-005646-xhx9pzhj 3944 4 MOF MOF NNP cord-005646-xhx9pzhj 3944 5 ( ( -LRB- cord-005646-xhx9pzhj 3944 6 Multiorgan Multiorgan NNP cord-005646-xhx9pzhj 3944 7 failure failure NN cord-005646-xhx9pzhj 3944 8 ) ) -RRB- cord-005646-xhx9pzhj 3944 9 died die VBD cord-005646-xhx9pzhj 3944 10 . . . cord-005646-xhx9pzhj 3945 1 72 72 CD cord-005646-xhx9pzhj 3945 2 % % NN cord-005646-xhx9pzhj 3945 3 needed need VBD cord-005646-xhx9pzhj 3945 4 mechanical mechanical JJ cord-005646-xhx9pzhj 3945 5 ventilation ventilation NN cord-005646-xhx9pzhj 3945 6 . . . cord-005646-xhx9pzhj 3946 1 The the DT cord-005646-xhx9pzhj 3946 2 average average JJ cord-005646-xhx9pzhj 3946 3 time time NN cord-005646-xhx9pzhj 3946 4 elapsed elapse VBN cord-005646-xhx9pzhj 3946 5 from from IN cord-005646-xhx9pzhj 3946 6 PICU PICU NNP cord-005646-xhx9pzhj 3946 7 admission admission NN cord-005646-xhx9pzhj 3946 8 to to IN cord-005646-xhx9pzhj 3946 9 initiation initiation NN cord-005646-xhx9pzhj 3946 10 of of IN cord-005646-xhx9pzhj 3946 11 EN EN NNP cord-005646-xhx9pzhj 3946 12 was be VBD cord-005646-xhx9pzhj 3946 13 2.1 2.1 CD cord-005646-xhx9pzhj 3946 14 days day NNS cord-005646-xhx9pzhj 3947 1 ( ( -LRB- cord-005646-xhx9pzhj 3947 2 range range NN cord-005646-xhx9pzhj 3947 3 1 1 CD cord-005646-xhx9pzhj 3947 4 to to IN cord-005646-xhx9pzhj 3947 5 7 7 CD cord-005646-xhx9pzhj 3947 6 ) ) -RRB- cord-005646-xhx9pzhj 3947 7 and and CC cord-005646-xhx9pzhj 3947 8 the the DT cord-005646-xhx9pzhj 3947 9 average average JJ cord-005646-xhx9pzhj 3947 10 duration duration NN cord-005646-xhx9pzhj 3947 11 of of IN cord-005646-xhx9pzhj 3947 12 the the DT cord-005646-xhx9pzhj 3947 13 EN EN NNP cord-005646-xhx9pzhj 3947 14 was be VBD cord-005646-xhx9pzhj 3947 15 7.3 7.3 CD cord-005646-xhx9pzhj 3947 16 days day NNS cord-005646-xhx9pzhj 3947 17 ( ( -LRB- cord-005646-xhx9pzhj 3947 18 range range VBP cord-005646-xhx9pzhj 3947 19 3 3 CD cord-005646-xhx9pzhj 3947 20 to to IN cord-005646-xhx9pzhj 3947 21 t4 t4 NNP cord-005646-xhx9pzhj 3947 22 ) ) -RRB- cord-005646-xhx9pzhj 3947 23 . . . cord-005646-xhx9pzhj 3948 1 The the DT cord-005646-xhx9pzhj 3948 2 average average JJ cord-005646-xhx9pzhj 3948 3 time time NN cord-005646-xhx9pzhj 3948 4 to to TO cord-005646-xhx9pzhj 3948 5 meet meet VB cord-005646-xhx9pzhj 3948 6 the the DT cord-005646-xhx9pzhj 3948 7 nutritional nutritional JJ cord-005646-xhx9pzhj 3948 8 objective objective NN cord-005646-xhx9pzhj 3948 9 was be VBD cord-005646-xhx9pzhj 3948 10 2 2 CD cord-005646-xhx9pzhj 3948 11 days day NNS cord-005646-xhx9pzhj 3948 12 ( ( -LRB- cord-005646-xhx9pzhj 3948 13 range range VBP cord-005646-xhx9pzhj 3948 14 1 1 CD cord-005646-xhx9pzhj 3948 15 to to IN cord-005646-xhx9pzhj 3948 16 3 3 CD cord-005646-xhx9pzhj 3948 17 ) ) -RRB- cord-005646-xhx9pzhj 3948 18 . . . cord-005646-xhx9pzhj 3949 1 The the DT cord-005646-xhx9pzhj 3949 2 selected select VBN cord-005646-xhx9pzhj 3949 3 formula formula NN cord-005646-xhx9pzhj 3949 4 were be VBD cord-005646-xhx9pzhj 3949 5 : : : cord-005646-xhx9pzhj 3949 6 lactose lactose VBG cord-005646-xhx9pzhj 3949 7 free free JJ cord-005646-xhx9pzhj 3949 8 infant infant NN cord-005646-xhx9pzhj 3949 9 formula formula NN cord-005646-xhx9pzhj 3949 10 in in IN cord-005646-xhx9pzhj 3949 11 10 10 CD cord-005646-xhx9pzhj 3949 12 patients patient NNS cord-005646-xhx9pzhj 3949 13 , , , cord-005646-xhx9pzhj 3949 14 elemental elemental JJ cord-005646-xhx9pzhj 3949 15 diet diet NN cord-005646-xhx9pzhj 3949 16 in in IN cord-005646-xhx9pzhj 3949 17 8 8 CD cord-005646-xhx9pzhj 3949 18 , , , cord-005646-xhx9pzhj 3949 19 Pediasure Pediasure NNP cord-005646-xhx9pzhj 3949 20 in in IN cord-005646-xhx9pzhj 3949 21 16 16 CD cord-005646-xhx9pzhj 3949 22 and and CC cord-005646-xhx9pzhj 3949 23 Jevity Jevity NNP cord-005646-xhx9pzhj 3949 24 in in IN cord-005646-xhx9pzhj 3949 25 2 2 CD cord-005646-xhx9pzhj 3949 26 . . . cord-005646-xhx9pzhj 3950 1 We -PRON- PRP cord-005646-xhx9pzhj 3950 2 recorded record VBD cord-005646-xhx9pzhj 3950 3 vomiting vomit VBG cord-005646-xhx9pzhj 3950 4 in in IN cord-005646-xhx9pzhj 3950 5 4 4 CD cord-005646-xhx9pzhj 3950 6 patients patient NNS cord-005646-xhx9pzhj 3950 7 , , , cord-005646-xhx9pzhj 3950 8 diarrhea diarrhea NN cord-005646-xhx9pzhj 3950 9 in in IN cord-005646-xhx9pzhj 3950 10 5 5 CD cord-005646-xhx9pzhj 3950 11 and and CC cord-005646-xhx9pzhj 3950 12 constipation constipation NN cord-005646-xhx9pzhj 3950 13 in in IN cord-005646-xhx9pzhj 3950 14 4 4 CD cord-005646-xhx9pzhj 3950 15 . . . cord-005646-xhx9pzhj 3951 1 None none NN cord-005646-xhx9pzhj 3951 2 of of IN cord-005646-xhx9pzhj 3951 3 them -PRON- PRP cord-005646-xhx9pzhj 3951 4 forced force VBD cord-005646-xhx9pzhj 3951 5 the the DT cord-005646-xhx9pzhj 3951 6 EN EN NNP cord-005646-xhx9pzhj 3951 7 suspension suspension NN cord-005646-xhx9pzhj 3951 8 . . . cord-005646-xhx9pzhj 3952 1 We -PRON- PRP cord-005646-xhx9pzhj 3952 2 did do VBD cord-005646-xhx9pzhj 3952 3 n't not RB cord-005646-xhx9pzhj 3952 4 recorded record VBN cord-005646-xhx9pzhj 3952 5 any any DT cord-005646-xhx9pzhj 3952 6 case case NN cord-005646-xhx9pzhj 3952 7 of of IN cord-005646-xhx9pzhj 3952 8 ~spiration ~spiration NNP cord-005646-xhx9pzhj 3952 9 or or CC cord-005646-xhx9pzhj 3952 10 pneumonia pneumonia NN cord-005646-xhx9pzhj 3952 11 . . . cord-005646-xhx9pzhj 3953 1 We -PRON- PRP cord-005646-xhx9pzhj 3953 2 found find VBD cord-005646-xhx9pzhj 3953 3 no no DT cord-005646-xhx9pzhj 3953 4 relation relation NN cord-005646-xhx9pzhj 3953 5 between between IN cord-005646-xhx9pzhj 3953 6 drugs drug NNS cord-005646-xhx9pzhj 3953 7 , , , cord-005646-xhx9pzhj 3953 8 selected select VBN cord-005646-xhx9pzhj 3953 9 formula formula NN cord-005646-xhx9pzhj 3953 10 and and CC cord-005646-xhx9pzhj 3953 11 complications complication NNS cord-005646-xhx9pzhj 3953 12 . . . cord-005646-xhx9pzhj 3954 1 We -PRON- PRP cord-005646-xhx9pzhj 3954 2 think think VBP cord-005646-xhx9pzhj 3954 3 that that IN cord-005646-xhx9pzhj 3954 4 EN EN NNP cord-005646-xhx9pzhj 3954 5 may may MD cord-005646-xhx9pzhj 3954 6 be be VB cord-005646-xhx9pzhj 3954 7 a a DT cord-005646-xhx9pzhj 3954 8 safe safe JJ cord-005646-xhx9pzhj 3954 9 and and CC cord-005646-xhx9pzhj 3954 10 well well RB cord-005646-xhx9pzhj 3954 11 tolerated tolerate VBN cord-005646-xhx9pzhj 3954 12 procedure procedure NN cord-005646-xhx9pzhj 3954 13 at at IN cord-005646-xhx9pzhj 3954 14 the the DT cord-005646-xhx9pzhj 3954 15 PICU PICU NNP cord-005646-xhx9pzhj 3954 16 setting setting NN cord-005646-xhx9pzhj 3954 17 . . . cord-005646-xhx9pzhj 3955 1 Generation generation NN cord-005646-xhx9pzhj 3955 2 of of IN cord-005646-xhx9pzhj 3955 3 free free JJ cord-005646-xhx9pzhj 3955 4 radicals radical NNS cord-005646-xhx9pzhj 3955 5 in in IN cord-005646-xhx9pzhj 3955 6 Iipid Iipid NNP cord-005646-xhx9pzhj 3955 7 emulsions emulsion NNS cord-005646-xhx9pzhj 3955 8 used use VBN cord-005646-xhx9pzhj 3955 9 in in IN cord-005646-xhx9pzhj 3955 10 parenterai parenterai NN cord-005646-xhx9pzhj 3955 11 nutrition nutrition NN cord-005646-xhx9pzhj 3955 12 ( ( -LRB- cord-005646-xhx9pzhj 3955 13 PN PN NNP cord-005646-xhx9pzhj 3955 14 ) ) -RRB- cord-005646-xhx9pzhj 3955 15 has have VBZ cord-005646-xhx9pzhj 3955 16 been be VBN cord-005646-xhx9pzhj 3955 17 described describe VBN cord-005646-xhx9pzhj 3955 18 recently recently RB cord-005646-xhx9pzhj 3955 19 . . . cord-005646-xhx9pzhj 3956 1 This this DT cord-005646-xhx9pzhj 3956 2 seems seem VBZ cord-005646-xhx9pzhj 3956 3 to to TO cord-005646-xhx9pzhj 3956 4 be be VB cord-005646-xhx9pzhj 3956 5 due due JJ cord-005646-xhx9pzhj 3956 6 to to IN cord-005646-xhx9pzhj 3956 7 high high JJ cord-005646-xhx9pzhj 3956 8 polyunsaturated polyunsaturated JJ cord-005646-xhx9pzhj 3956 9 fatty fatty JJ cord-005646-xhx9pzhj 3956 10 acid acid NN cord-005646-xhx9pzhj 3956 11 content content NN cord-005646-xhx9pzhj 3956 12 . . . cord-005646-xhx9pzhj 3957 1 We -PRON- PRP cord-005646-xhx9pzhj 3957 2 studied study VBD cord-005646-xhx9pzhj 3957 3 lipoperoxidation lipoperoxidation NN cord-005646-xhx9pzhj 3957 4 status status NN cord-005646-xhx9pzhj 3957 5 and and CC cord-005646-xhx9pzhj 3957 6 antioxidant antioxidant JJ cord-005646-xhx9pzhj 3957 7 parameters parameter NNS cord-005646-xhx9pzhj 3957 8 presurgically presurgically RB cord-005646-xhx9pzhj 3957 9 and and CC cord-005646-xhx9pzhj 3957 10 through through IN cord-005646-xhx9pzhj 3957 11 the the DT cord-005646-xhx9pzhj 3957 12 postoperative postoperative JJ cord-005646-xhx9pzhj 3957 13 period period NN cord-005646-xhx9pzhj 3957 14 ( ( -LRB- cord-005646-xhx9pzhj 3957 15 5 5 CD cord-005646-xhx9pzhj 3957 16 days day NNS cord-005646-xhx9pzhj 3957 17 ) ) -RRB- cord-005646-xhx9pzhj 3957 18 in in IN cord-005646-xhx9pzhj 3957 19 a a DT cord-005646-xhx9pzhj 3957 20 group group NN cord-005646-xhx9pzhj 3957 21 of of IN cord-005646-xhx9pzhj 3957 22 twelve twelve CD cord-005646-xhx9pzhj 3957 23 children child NNS cord-005646-xhx9pzhj 3957 24 ( ( -LRB- cord-005646-xhx9pzhj 3957 25 ranging range VBG cord-005646-xhx9pzhj 3957 26 from from IN cord-005646-xhx9pzhj 3957 27 4 4 CD cord-005646-xhx9pzhj 3957 28 months month NNS cord-005646-xhx9pzhj 3957 29 to to IN cord-005646-xhx9pzhj 3957 30 12 12 CD cord-005646-xhx9pzhj 3957 31 years year NNS cord-005646-xhx9pzhj 3957 32 of of IN cord-005646-xhx9pzhj 3957 33 age age NN cord-005646-xhx9pzhj 3957 34 ) ) -RRB- cord-005646-xhx9pzhj 3957 35 , , , cord-005646-xhx9pzhj 3957 36 who who WP cord-005646-xhx9pzhj 3957 37 underwent undergo VBD cord-005646-xhx9pzhj 3957 38 heart heart NN cord-005646-xhx9pzhj 3957 39 surgery surgery NN cord-005646-xhx9pzhj 3957 40 and and CC cord-005646-xhx9pzhj 3957 41 received receive VBD cord-005646-xhx9pzhj 3957 42 nutritional nutritional JJ cord-005646-xhx9pzhj 3957 43 support support NN cord-005646-xhx9pzhj 3957 44 with with IN cord-005646-xhx9pzhj 3957 45 PN PN NNP cord-005646-xhx9pzhj 3957 46 . . . cord-005646-xhx9pzhj 3958 1 Malondiaidehyde Malondiaidehyde NNP cord-005646-xhx9pzhj 3958 2 ( ( -LRB- cord-005646-xhx9pzhj 3958 3 MDA MDA NNP cord-005646-xhx9pzhj 3958 4 ) ) -RRB- cord-005646-xhx9pzhj 3958 5 , , , cord-005646-xhx9pzhj 3958 6 an an DT cord-005646-xhx9pzhj 3958 7 end end NN cord-005646-xhx9pzhj 3958 8 product product NN cord-005646-xhx9pzhj 3958 9 of of IN cord-005646-xhx9pzhj 3958 10 lipid lipid NN cord-005646-xhx9pzhj 3958 11 peroxidation peroxidation NN cord-005646-xhx9pzhj 3958 12 was be VBD cord-005646-xhx9pzhj 3958 13 used use VBN cord-005646-xhx9pzhj 3958 14 as as IN cord-005646-xhx9pzhj 3958 15 a a DT cord-005646-xhx9pzhj 3958 16 marker marker NN cord-005646-xhx9pzhj 3958 17 of of IN cord-005646-xhx9pzhj 3958 18 oxidative oxidative JJ cord-005646-xhx9pzhj 3958 19 stress stress NN cord-005646-xhx9pzhj 3958 20 . . . cord-005646-xhx9pzhj 3959 1 It -PRON- PRP cord-005646-xhx9pzhj 3959 2 was be VBD cord-005646-xhx9pzhj 3959 3 determined determine VBN cord-005646-xhx9pzhj 3959 4 by by IN cord-005646-xhx9pzhj 3959 5 the the DT cord-005646-xhx9pzhj 3959 6 Yagi Yagi NNP cord-005646-xhx9pzhj 3959 7 spectrofluorometric spectrofluorometric JJ cord-005646-xhx9pzhj 3959 8 method method NN cord-005646-xhx9pzhj 3959 9 . . . cord-005646-xhx9pzhj 3960 1 Antioxidant antioxidant JJ cord-005646-xhx9pzhj 3960 2 activity activity NN cord-005646-xhx9pzhj 3960 3 was be VBD cord-005646-xhx9pzhj 3960 4 measured measure VBN cord-005646-xhx9pzhj 3960 5 with with IN cord-005646-xhx9pzhj 3960 6 an an DT cord-005646-xhx9pzhj 3960 7 assay assay NN cord-005646-xhx9pzhj 3960 8 based base VBN cord-005646-xhx9pzhj 3960 9 on on IN cord-005646-xhx9pzhj 3960 10 the the DT cord-005646-xhx9pzhj 3960 11 inhibition inhibition NN cord-005646-xhx9pzhj 3960 12 of of IN cord-005646-xhx9pzhj 3960 13 spontaneous spontaneous JJ cord-005646-xhx9pzhj 3960 14 autooxidation autooxidation NN cord-005646-xhx9pzhj 3960 15 of of IN cord-005646-xhx9pzhj 3960 16 a a DT cord-005646-xhx9pzhj 3960 17 brain brain NN cord-005646-xhx9pzhj 3960 18 homogenate homogenate NN cord-005646-xhx9pzhj 3960 19 , , , cord-005646-xhx9pzhj 3960 20 and and CC cord-005646-xhx9pzhj 3960 21 vitamin vitamin NN cord-005646-xhx9pzhj 3960 22 E e NN cord-005646-xhx9pzhj 3960 23 in in IN cord-005646-xhx9pzhj 3960 24 serum serum NN cord-005646-xhx9pzhj 3960 25 by by IN cord-005646-xhx9pzhj 3960 26 the the DT cord-005646-xhx9pzhj 3960 27 technique technique NN cord-005646-xhx9pzhj 3960 28 of of IN cord-005646-xhx9pzhj 3960 29 Hansen Hansen NNP cord-005646-xhx9pzhj 3960 30 and and CC cord-005646-xhx9pzhj 3960 31 Warick Warick NNP cord-005646-xhx9pzhj 3960 32 . . . cord-005646-xhx9pzhj 3961 1 Erythrocyte Erythrocyte NNP cord-005646-xhx9pzhj 3961 2 MDA MDA NNP cord-005646-xhx9pzhj 3961 3 release release NN cord-005646-xhx9pzhj 3961 4 fonowing fonowe VBG cord-005646-xhx9pzhj 3961 5 incubation incubation NN cord-005646-xhx9pzhj 3961 6 in in IN cord-005646-xhx9pzhj 3961 7 HzO hzo NN cord-005646-xhx9pzhj 3961 8 2 2 CD cord-005646-xhx9pzhj 3961 9 in in IN cord-005646-xhx9pzhj 3961 10 vitro vitro FW cord-005646-xhx9pzhj 3961 11 was be VBD cord-005646-xhx9pzhj 3961 12 used use VBN cord-005646-xhx9pzhj 3961 13 as as IN cord-005646-xhx9pzhj 3961 14 a a DT cord-005646-xhx9pzhj 3961 15 functional functional JJ cord-005646-xhx9pzhj 3961 16 measure measure NN cord-005646-xhx9pzhj 3961 17 of of IN cord-005646-xhx9pzhj 3961 18 tissue tissue NN cord-005646-xhx9pzhj 3961 19 vitamin vitamin NN cord-005646-xhx9pzhj 3961 20 E e NN cord-005646-xhx9pzhj 3961 21 levels level NNS cord-005646-xhx9pzhj 3961 22 . . . cord-005646-xhx9pzhj 3962 1 Data datum NNS cord-005646-xhx9pzhj 3962 2 were be VBD cord-005646-xhx9pzhj 3962 3 compared compare VBN cord-005646-xhx9pzhj 3962 4 using use VBG cord-005646-xhx9pzhj 3962 5 one one CD cord-005646-xhx9pzhj 3962 6 - - HYPH cord-005646-xhx9pzhj 3962 7 way way NN cord-005646-xhx9pzhj 3962 8 variance variance NN cord-005646-xhx9pzhj 3962 9 analysis analysis NN cord-005646-xhx9pzhj 3962 10 . . . cord-005646-xhx9pzhj 3963 1 There there EX cord-005646-xhx9pzhj 3963 2 was be VBD cord-005646-xhx9pzhj 3963 3 not not RB cord-005646-xhx9pzhj 3963 4 significant significant JJ cord-005646-xhx9pzhj 3963 5 differences difference NNS cord-005646-xhx9pzhj 3963 6 in in IN cord-005646-xhx9pzhj 3963 7 the the DT cord-005646-xhx9pzhj 3963 8 plasma plasma NN cord-005646-xhx9pzhj 3963 9 MDA MDA NNP cord-005646-xhx9pzhj 3963 10 production production NN cord-005646-xhx9pzhj 3963 11 among among IN cord-005646-xhx9pzhj 3963 12 the the DT cord-005646-xhx9pzhj 3963 13 values value NNS cord-005646-xhx9pzhj 3963 14 obtained obtain VBN cord-005646-xhx9pzhj 3963 15 before before IN cord-005646-xhx9pzhj 3963 16 surgery surgery NN cord-005646-xhx9pzhj 3963 17 ( ( -LRB- cord-005646-xhx9pzhj 3963 18 3 3 CD cord-005646-xhx9pzhj 3964 1 : : : cord-005646-xhx9pzhj 3964 2 t t NN cord-005646-xhx9pzhj 3964 3 : : : cord-005646-xhx9pzhj 3964 4 0.5 0.5 CD cord-005646-xhx9pzhj 3964 5 nmol nmol JJ cord-005646-xhx9pzhj 3964 6 / / SYM cord-005646-xhx9pzhj 3964 7 mL mL NNP cord-005646-xhx9pzhj 3964 8 ) ) -RRB- cord-005646-xhx9pzhj 3964 9 , , , cord-005646-xhx9pzhj 3964 10 postoperative postoperative JJ cord-005646-xhx9pzhj 3964 11 pre pre JJ cord-005646-xhx9pzhj 3964 12 - - JJ cord-005646-xhx9pzhj 3964 13 PN pn JJ cord-005646-xhx9pzhj 3964 14 ( ( -LRB- cord-005646-xhx9pzhj 3964 15 3.5 3.5 CD cord-005646-xhx9pzhj 3964 16 + + CC cord-005646-xhx9pzhj 3964 17 _ _ NN cord-005646-xhx9pzhj 3964 18 0.6 0.6 CD cord-005646-xhx9pzhj 3964 19 nmol nmol JJ cord-005646-xhx9pzhj 3964 20 / / SYM cord-005646-xhx9pzhj 3964 21 mL ml NN cord-005646-xhx9pzhj 3964 22 ) ) -RRB- cord-005646-xhx9pzhj 3964 23 and and CC cord-005646-xhx9pzhj 3964 24 through through IN cord-005646-xhx9pzhj 3964 25 the the DT cord-005646-xhx9pzhj 3964 26 course course NN cord-005646-xhx9pzhj 3964 27 of of IN cord-005646-xhx9pzhj 3964 28 PN PN NNP cord-005646-xhx9pzhj 3964 29 ( ( -LRB- cord-005646-xhx9pzhj 3964 30 3.5 3.5 CD cord-005646-xhx9pzhj 3964 31 5:0.6 5:0.6 CD cord-005646-xhx9pzhj 3964 32 nmol nmol JJ cord-005646-xhx9pzhj 3964 33 / / SYM cord-005646-xhx9pzhj 3964 34 mL ml NN cord-005646-xhx9pzhj 3964 35 ) ) -RRB- cord-005646-xhx9pzhj 3964 36 . . . cord-005646-xhx9pzhj 3965 1 Levels level NNS cord-005646-xhx9pzhj 3965 2 of of IN cord-005646-xhx9pzhj 3965 3 vitamin vitamin NN cord-005646-xhx9pzhj 3965 4 E e NN cord-005646-xhx9pzhj 3965 5 previous previous JJ cord-005646-xhx9pzhj 3965 6 to to IN cord-005646-xhx9pzhj 3965 7 surgery surgery NN cord-005646-xhx9pzhj 3965 8 were be VBD cord-005646-xhx9pzhj 3965 9 5,1 5,1 CD cord-005646-xhx9pzhj 3965 10 5:1.1 5:1.1 CD cord-005646-xhx9pzhj 3965 11 # # NN cord-005646-xhx9pzhj 3965 12 g g NN cord-005646-xhx9pzhj 3965 13 / / SYM cord-005646-xhx9pzhj 3965 14 mL ml NN cord-005646-xhx9pzhj 3965 15 and and CC cord-005646-xhx9pzhj 3965 16 decreased decrease VBD cord-005646-xhx9pzhj 3965 17 to to IN cord-005646-xhx9pzhj 3965 18 3.2 3.2 CD cord-005646-xhx9pzhj 3965 19 _ _ NN cord-005646-xhx9pzhj 3965 20 + + CC cord-005646-xhx9pzhj 3966 1 1.4 1.4 CD cord-005646-xhx9pzhj 3966 2 # # NN cord-005646-xhx9pzhj 3966 3 g g NN cord-005646-xhx9pzhj 3966 4 / / SYM cord-005646-xhx9pzhj 3966 5 mL ml NN cord-005646-xhx9pzhj 3966 6 at at IN cord-005646-xhx9pzhj 3966 7 24 24 CD cord-005646-xhx9pzhj 3966 8 hours hour NNS cord-005646-xhx9pzhj 3966 9 post post NN cord-005646-xhx9pzhj 3966 10 - - NN cord-005646-xhx9pzhj 3966 11 surgery surgery NN cord-005646-xhx9pzhj 3966 12 before before IN cord-005646-xhx9pzhj 3966 13 starting start VBG cord-005646-xhx9pzhj 3966 14 PN PN NNP cord-005646-xhx9pzhj 3966 15 . . . cord-005646-xhx9pzhj 3967 1 While while IN cord-005646-xhx9pzhj 3967 2 receiving receive VBG cord-005646-xhx9pzhj 3967 3 PN pn NN cord-005646-xhx9pzhj 3967 4 , , , cord-005646-xhx9pzhj 3967 5 concentrations concentration NNS cord-005646-xhx9pzhj 3967 6 of of IN cord-005646-xhx9pzhj 3967 7 vitamin vitamin NN cord-005646-xhx9pzhj 3967 8 E e NN cord-005646-xhx9pzhj 3967 9 increased increase VBD cord-005646-xhx9pzhj 3967 10 progressively progressively RB cord-005646-xhx9pzhj 3967 11 up up IN cord-005646-xhx9pzhj 3967 12 to to TO cord-005646-xhx9pzhj 3967 13 7 7 CD cord-005646-xhx9pzhj 3967 14 + + SYM cord-005646-xhx9pzhj 3967 15 4 4 CD cord-005646-xhx9pzhj 3967 16 . . . cord-005646-xhx9pzhj 3968 1 l l NN cord-005646-xhx9pzhj 3968 2 # # NN cord-005646-xhx9pzhj 3968 3 g g NN cord-005646-xhx9pzhj 3968 4 / / SYM cord-005646-xhx9pzhj 3968 5 mL ml NN cord-005646-xhx9pzhj 3969 1 ( ( -LRB- cord-005646-xhx9pzhj 3969 2 p p NN cord-005646-xhx9pzhj 3969 3 = = SYM cord-005646-xhx9pzhj 3969 4 0.08 0.08 CD cord-005646-xhx9pzhj 3969 5 ) ) -RRB- cord-005646-xhx9pzhj 3969 6 . . . cord-005646-xhx9pzhj 3970 1 Pre pre JJ cord-005646-xhx9pzhj 3970 2 - - JJ cord-005646-xhx9pzhj 3970 3 surgicai surgicai JJ cord-005646-xhx9pzhj 3970 4 plasma plasma NN cord-005646-xhx9pzhj 3970 5 antioxidaut antioxidaut NNP cord-005646-xhx9pzhj 3970 6 activity activity NN cord-005646-xhx9pzhj 3970 7 values value NNS cord-005646-xhx9pzhj 3970 8 ( ( -LRB- cord-005646-xhx9pzhj 3970 9 72 72 CD cord-005646-xhx9pzhj 3970 10 : : : cord-005646-xhx9pzhj 3970 11 I -PRON- PRP cord-005646-xhx9pzhj 3970 12 : : : cord-005646-xhx9pzhj 3970 13 11 11 CD cord-005646-xhx9pzhj 3970 14 % % NN cord-005646-xhx9pzhj 3970 15 ) ) -RRB- cord-005646-xhx9pzhj 3970 16 dimiuished dimiuishe VBN cord-005646-xhx9pzhj 3970 17 in in IN cord-005646-xhx9pzhj 3970 18 the the DT cord-005646-xhx9pzhj 3970 19 first first JJ cord-005646-xhx9pzhj 3970 20 postoperative postoperative JJ cord-005646-xhx9pzhj 3970 21 day day NN cord-005646-xhx9pzhj 3970 22 ( ( -LRB- cord-005646-xhx9pzhj 3970 23 56 56 CD cord-005646-xhx9pzhj 3970 24 _ _ NN cord-005646-xhx9pzhj 3970 25 + + CC cord-005646-xhx9pzhj 3970 26 9.5 9.5 CD cord-005646-xhx9pzhj 3970 27 % % NN cord-005646-xhx9pzhj 3970 28 ) ) -RRB- cord-005646-xhx9pzhj 3970 29 and and CC cord-005646-xhx9pzhj 3970 30 then then RB cord-005646-xhx9pzhj 3970 31 showed show VBD cord-005646-xhx9pzhj 3970 32 a a DT cord-005646-xhx9pzhj 3970 33 clear clear JJ cord-005646-xhx9pzhj 3970 34 increasing increasing JJ cord-005646-xhx9pzhj 3970 35 tendency tendency NN cord-005646-xhx9pzhj 3970 36 , , , cord-005646-xhx9pzhj 3970 37 directly directly RB cord-005646-xhx9pzhj 3970 38 correlated correlate VBN cord-005646-xhx9pzhj 3970 39 with with IN cord-005646-xhx9pzhj 3970 40 that that DT cord-005646-xhx9pzhj 3970 41 observed observe VBN cord-005646-xhx9pzhj 3970 42 in in IN cord-005646-xhx9pzhj 3970 43 vitamin vitamin NN cord-005646-xhx9pzhj 3970 44 E e NN cord-005646-xhx9pzhj 3970 45 levels level NNS cord-005646-xhx9pzhj 3970 46 . . . cord-005646-xhx9pzhj 3971 1 The the DT cord-005646-xhx9pzhj 3971 2 measurements measurement NNS cord-005646-xhx9pzhj 3971 3 of of IN cord-005646-xhx9pzhj 3971 4 the the DT cord-005646-xhx9pzhj 3971 5 maximal maximal JJ cord-005646-xhx9pzhj 3971 6 percentage percentage NN cord-005646-xhx9pzhj 3971 7 of of IN cord-005646-xhx9pzhj 3971 8 MDA MDA NNP cord-005646-xhx9pzhj 3971 9 release release NN cord-005646-xhx9pzhj 3971 10 of of IN cord-005646-xhx9pzhj 3971 11 erythrocytes erythrocyte NNS cord-005646-xhx9pzhj 3971 12 in in IN cord-005646-xhx9pzhj 3971 13 vitro vitro FW cord-005646-xhx9pzhj 3971 14 , , , cord-005646-xhx9pzhj 3971 15 showed show VBD cord-005646-xhx9pzhj 3971 16 an an DT cord-005646-xhx9pzhj 3971 17 inverse inverse JJ cord-005646-xhx9pzhj 3971 18 relationship relationship NN cord-005646-xhx9pzhj 3971 19 with with IN cord-005646-xhx9pzhj 3971 20 plasma plasma NN cord-005646-xhx9pzhj 3971 21 vitamin vitamin NN cord-005646-xhx9pzhj 3971 22 E e NN cord-005646-xhx9pzhj 3971 23 levels level NNS cord-005646-xhx9pzhj 3971 24 and and CC cord-005646-xhx9pzhj 3971 25 with with IN cord-005646-xhx9pzhj 3971 26 the the DT cord-005646-xhx9pzhj 3971 27 plasma plasma NN cord-005646-xhx9pzhj 3971 28 antioxidant antioxidant NN cord-005646-xhx9pzhj 3971 29 capacity capacity NN cord-005646-xhx9pzhj 3971 30 : : : cord-005646-xhx9pzhj 3971 31 preoperative preoperative JJ cord-005646-xhx9pzhj 3971 32 5.8 5.8 CD cord-005646-xhx9pzhj 3971 33 + + SYM cord-005646-xhx9pzhj 3971 34 2.4 2.4 CD cord-005646-xhx9pzhj 3971 35 % % NN cord-005646-xhx9pzhj 3971 36 and and CC cord-005646-xhx9pzhj 3971 37 postoperative postoperative JJ cord-005646-xhx9pzhj 3971 38 descending descend VBG cord-005646-xhx9pzhj 3971 39 from from IN cord-005646-xhx9pzhj 3971 40 20.5 20.5 CD cord-005646-xhx9pzhj 3971 41 + + SYM cord-005646-xhx9pzhj 3971 42 14 14 CD cord-005646-xhx9pzhj 3971 43 % % NN cord-005646-xhx9pzhj 3971 44 to to TO cord-005646-xhx9pzhj 3971 45 12 12 CD cord-005646-xhx9pzhj 3971 46 _ _ NN cord-005646-xhx9pzhj 3972 1 + + CC cord-005646-xhx9pzhj 3973 1 9.5 9.5 CD cord-005646-xhx9pzhj 3973 2 % % NN cord-005646-xhx9pzhj 3973 3 . . . cord-005646-xhx9pzhj 3974 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 3974 2 results result NNS cord-005646-xhx9pzhj 3974 3 indicate indicate VBP cord-005646-xhx9pzhj 3974 4 that that IN cord-005646-xhx9pzhj 3974 5 during during IN cord-005646-xhx9pzhj 3974 6 surgery surgery NN cord-005646-xhx9pzhj 3974 7 and and CC cord-005646-xhx9pzhj 3974 8 within within IN cord-005646-xhx9pzhj 3974 9 24 24 CD cord-005646-xhx9pzhj 3974 10 hours hour NNS cord-005646-xhx9pzhj 3974 11 postsurgery postsurgery NN cord-005646-xhx9pzhj 3974 12 , , , cord-005646-xhx9pzhj 3974 13 a a DT cord-005646-xhx9pzhj 3974 14 decline decline NN cord-005646-xhx9pzhj 3974 15 in in IN cord-005646-xhx9pzhj 3974 16 antioxidant antioxidant JJ cord-005646-xhx9pzhj 3974 17 defenses defense NNS cord-005646-xhx9pzhj 3974 18 occurs occur VBZ cord-005646-xhx9pzhj 3974 19 , , , cord-005646-xhx9pzhj 3974 20 In in IN cord-005646-xhx9pzhj 3974 21 the the DT cord-005646-xhx9pzhj 3974 22 postoperative postoperative JJ cord-005646-xhx9pzhj 3974 23 period period NN cord-005646-xhx9pzhj 3974 24 , , , cord-005646-xhx9pzhj 3974 25 while while IN cord-005646-xhx9pzhj 3974 26 patients patient NNS cord-005646-xhx9pzhj 3974 27 are be VBP cord-005646-xhx9pzhj 3974 28 on on IN cord-005646-xhx9pzhj 3974 29 PN PN NNP cord-005646-xhx9pzhj 3974 30 and and CC cord-005646-xhx9pzhj 3974 31 taldng taldng NN cord-005646-xhx9pzhj 3974 32 into into IN cord-005646-xhx9pzhj 3974 33 account account NN cord-005646-xhx9pzhj 3975 1 our -PRON- PRP$ cord-005646-xhx9pzhj 3975 2 obtained obtain VBN cord-005646-xhx9pzhj 3975 3 data datum NNS cord-005646-xhx9pzhj 3975 4 : : : cord-005646-xhx9pzhj 3975 5 the the DT cord-005646-xhx9pzhj 3975 6 unaltered unaltered JJ cord-005646-xhx9pzhj 3975 7 MDA MDA NNP cord-005646-xhx9pzhj 3975 8 values value NNS cord-005646-xhx9pzhj 3975 9 , , , cord-005646-xhx9pzhj 3975 10 the the DT cord-005646-xhx9pzhj 3975 11 rise rise NN cord-005646-xhx9pzhj 3975 12 of of IN cord-005646-xhx9pzhj 3975 13 plasma plasma NN cord-005646-xhx9pzhj 3975 14 vitamin vitamin NN cord-005646-xhx9pzhj 3975 15 E e NN cord-005646-xhx9pzhj 3975 16 levels level NNS cord-005646-xhx9pzhj 3975 17 , , , cord-005646-xhx9pzhj 3975 18 the the DT cord-005646-xhx9pzhj 3975 19 recovery recovery NN cord-005646-xhx9pzhj 3975 20 of of IN cord-005646-xhx9pzhj 3975 21 both both DT cord-005646-xhx9pzhj 3975 22 functional functional JJ cord-005646-xhx9pzhj 3975 23 erythrocyte erythrocyte NN cord-005646-xhx9pzhj 3975 24 membrane membrane NN cord-005646-xhx9pzhj 3975 25 antioxidant antioxidant NN cord-005646-xhx9pzhj 3975 26 protection protection NN cord-005646-xhx9pzhj 3975 27 and and CC cord-005646-xhx9pzhj 3975 28 the the DT cord-005646-xhx9pzhj 3975 29 plasma plasma NN cord-005646-xhx9pzhj 3975 30 antioxidant antioxidant NN cord-005646-xhx9pzhj 3975 31 activity activity NN cord-005646-xhx9pzhj 3975 32 , , , cord-005646-xhx9pzhj 3975 33 they -PRON- PRP cord-005646-xhx9pzhj 3975 34 do do VBP cord-005646-xhx9pzhj 3975 35 reflect reflect VB cord-005646-xhx9pzhj 3975 36 that that IN cord-005646-xhx9pzhj 3975 37 during during IN cord-005646-xhx9pzhj 3975 38 the the DT cord-005646-xhx9pzhj 3975 39 intravenous intravenous JJ cord-005646-xhx9pzhj 3975 40 administration administration NN cord-005646-xhx9pzhj 3975 41 of of IN cord-005646-xhx9pzhj 3975 42 lipid lipid NN cord-005646-xhx9pzhj 3975 43 infusions infusion NNS cord-005646-xhx9pzhj 3975 44 , , , cord-005646-xhx9pzhj 3975 45 oxidative oxidative JJ cord-005646-xhx9pzhj 3975 46 damage damage NN cord-005646-xhx9pzhj 3975 47 does do VBZ cord-005646-xhx9pzhj 3975 48 not not RB cord-005646-xhx9pzhj 3975 49 occur occur VB cord-005646-xhx9pzhj 3975 50 , , , cord-005646-xhx9pzhj 3975 51 probably probably RB cord-005646-xhx9pzhj 3975 52 due due IN cord-005646-xhx9pzhj 3975 53 to to IN cord-005646-xhx9pzhj 3975 54 the the DT cord-005646-xhx9pzhj 3975 55 addition addition NN cord-005646-xhx9pzhj 3975 56 of of IN cord-005646-xhx9pzhj 3975 57 vitamin vitamin NN cord-005646-xhx9pzhj 3975 58 E e NN cord-005646-xhx9pzhj 3975 59 to to IN cord-005646-xhx9pzhj 3975 60 PN PN NNP cord-005646-xhx9pzhj 3975 61 solutions solution NNS cord-005646-xhx9pzhj 3975 62 in in IN cord-005646-xhx9pzhj 3975 63 order order NN cord-005646-xhx9pzhj 3975 64 to to TO cord-005646-xhx9pzhj 3975 65 avoid avoid VB cord-005646-xhx9pzhj 3975 66 autooxidation autooxidation NN cord-005646-xhx9pzhj 3975 67 of of IN cord-005646-xhx9pzhj 3975 68 lipid lipid NN cord-005646-xhx9pzhj 3975 69 emulsions emulsion NNS cord-005646-xhx9pzhj 3975 70 . . . cord-005646-xhx9pzhj 3976 1 Garnitine Garnitine NNP cord-005646-xhx9pzhj 3976 2 is be VBZ cord-005646-xhx9pzhj 3976 3 one one CD cord-005646-xhx9pzhj 3976 4 of of IN cord-005646-xhx9pzhj 3976 5 the the DT cord-005646-xhx9pzhj 3976 6 essential essential JJ cord-005646-xhx9pzhj 3976 7 nutrient nutrient NN cord-005646-xhx9pzhj 3976 8 in in IN cord-005646-xhx9pzhj 3976 9 the the DT cord-005646-xhx9pzhj 3976 10 diet diet NN cord-005646-xhx9pzhj 3976 11 of of IN cord-005646-xhx9pzhj 3976 12 newborn newborn JJ cord-005646-xhx9pzhj 3976 13 infants infant NNS cord-005646-xhx9pzhj 3976 14 . . . cord-005646-xhx9pzhj 3977 1 Mother mother NN cord-005646-xhx9pzhj 3977 2 's 's POS cord-005646-xhx9pzhj 3977 3 milk milk NN cord-005646-xhx9pzhj 3977 4 represents represent VBZ cord-005646-xhx9pzhj 3977 5 the the DT cord-005646-xhx9pzhj 3977 6 natural natural JJ cord-005646-xhx9pzhj 3977 7 eamitine eamitine NN cord-005646-xhx9pzhj 3977 8 source source NN cord-005646-xhx9pzhj 3977 9 for for IN cord-005646-xhx9pzhj 3977 10 the the DT cord-005646-xhx9pzhj 3977 11 newborn newborn JJ cord-005646-xhx9pzhj 3977 12 infants infant NNS cord-005646-xhx9pzhj 3977 13 . . . cord-005646-xhx9pzhj 3978 1 We -PRON- PRP cord-005646-xhx9pzhj 3978 2 studied study VBD cord-005646-xhx9pzhj 3978 3 enteral enteral JJ cord-005646-xhx9pzhj 3978 4 earnitine earnitine NN cord-005646-xhx9pzhj 3978 5 intake intake NN cord-005646-xhx9pzhj 3978 6 in in IN cord-005646-xhx9pzhj 3978 7 71 71 CD cord-005646-xhx9pzhj 3978 8 premature premature JJ cord-005646-xhx9pzhj 3978 9 infants infant NNS cord-005646-xhx9pzhj 3978 10 35 35 CD cord-005646-xhx9pzhj 3978 11 eutrophic eutrophic JJ cord-005646-xhx9pzhj 3978 12 ( ( -LRB- cord-005646-xhx9pzhj 3978 13 Eu Eu NNP cord-005646-xhx9pzhj 3978 14 ) ) -RRB- cord-005646-xhx9pzhj 3978 15 and and CC cord-005646-xhx9pzhj 3978 16 36 36 CD cord-005646-xhx9pzhj 3978 17 hypotrophic hypotrophic JJ cord-005646-xhx9pzhj 3978 18 ( ( -LRB- cord-005646-xhx9pzhj 3978 19 Hy Hy NNP cord-005646-xhx9pzhj 3978 20 ) ) -RRB- cord-005646-xhx9pzhj 3978 21 , , , cord-005646-xhx9pzhj 3978 22 fed feed VBN cord-005646-xhx9pzhj 3978 23 with with IN cord-005646-xhx9pzhj 3978 24 mothers mother NNS cord-005646-xhx9pzhj 3978 25 milk milk NN cord-005646-xhx9pzhj 3978 26 trough trough IN cord-005646-xhx9pzhj 3978 27 5 5 CD cord-005646-xhx9pzhj 3978 28 consecutive consecutive JJ cord-005646-xhx9pzhj 3978 29 days day NNS cord-005646-xhx9pzhj 3978 30 - - : cord-005646-xhx9pzhj 3978 31 from from IN cord-005646-xhx9pzhj 3978 32 fifth fifth JJ cord-005646-xhx9pzhj 3978 33 to to IN cord-005646-xhx9pzhj 3978 34 tenth tenth JJ cord-005646-xhx9pzhj 3978 35 day day NN cord-005646-xhx9pzhj 3978 36 of of IN cord-005646-xhx9pzhj 3978 37 life life NN cord-005646-xhx9pzhj 3978 38 . . . cord-005646-xhx9pzhj 3979 1 Mean mean JJ cord-005646-xhx9pzhj 3979 2 gestational gestational JJ cord-005646-xhx9pzhj 3979 3 age age NN cord-005646-xhx9pzhj 3979 4 was be VBD cord-005646-xhx9pzhj 3979 5 33 33 CD cord-005646-xhx9pzhj 3980 1 ( ( -LRB- cord-005646-xhx9pzhj 3980 2 range range NNP cord-005646-xhx9pzhj 3980 3 32 32 CD cord-005646-xhx9pzhj 3980 4 - - SYM cord-005646-xhx9pzhj 3980 5 36 36 CD cord-005646-xhx9pzhj 3980 6 ) ) -RRB- cord-005646-xhx9pzhj 3980 7 weeks week NNS cord-005646-xhx9pzhj 3980 8 for for IN cord-005646-xhx9pzhj 3980 9 Eu Eu NNP cord-005646-xhx9pzhj 3980 10 and and CC cord-005646-xhx9pzhj 3980 11 34 34 CD cord-005646-xhx9pzhj 3980 12 ( ( -LRB- cord-005646-xhx9pzhj 3980 13 range range NNP cord-005646-xhx9pzhj 3980 14 32 32 CD cord-005646-xhx9pzhj 3980 15 - - SYM cord-005646-xhx9pzhj 3980 16 36 36 CD cord-005646-xhx9pzhj 3980 17 ) ) -RRB- cord-005646-xhx9pzhj 3980 18 weeks week NNS cord-005646-xhx9pzhj 3980 19 for for IN cord-005646-xhx9pzhj 3980 20 Hy Hy NNP cord-005646-xhx9pzhj 3980 21 . . . cord-005646-xhx9pzhj 3981 1 Birth birth NN cord-005646-xhx9pzhj 3981 2 weight weight NN cord-005646-xhx9pzhj 3981 3 was be VBD cord-005646-xhx9pzhj 3981 4 ranged range VBN cord-005646-xhx9pzhj 3981 5 1430 1430 CD cord-005646-xhx9pzhj 3981 6 - - SYM cord-005646-xhx9pzhj 3981 7 2450 2450 CD cord-005646-xhx9pzhj 3981 8 g g NN cord-005646-xhx9pzhj 3981 9 for for IN cord-005646-xhx9pzhj 3981 10 Eu Eu NNP cord-005646-xhx9pzhj 3981 11 and and CC cord-005646-xhx9pzhj 3981 12 1250 1250 CD cord-005646-xhx9pzhj 3981 13 - - SYM cord-005646-xhx9pzhj 3981 14 2300 2300 CD cord-005646-xhx9pzhj 3981 15 g g NN cord-005646-xhx9pzhj 3981 16 for for IN cord-005646-xhx9pzhj 3981 17 Hy Hy NNP cord-005646-xhx9pzhj 3981 18 ( ( -LRB- cord-005646-xhx9pzhj 3981 19 p p NN cord-005646-xhx9pzhj 3981 20 < < XX cord-005646-xhx9pzhj 3981 21 0,05 0,05 NNP cord-005646-xhx9pzhj 3981 22 ) ) -RRB- cord-005646-xhx9pzhj 3981 23 . . . cord-005646-xhx9pzhj 3982 1 Breast breast NN cord-005646-xhx9pzhj 3982 2 milk milk NN cord-005646-xhx9pzhj 3982 3 carnitine carnitine NN cord-005646-xhx9pzhj 3982 4 concentration concentration NN cord-005646-xhx9pzhj 3982 5 was be VBD cord-005646-xhx9pzhj 3982 6 78,88 78,88 CD cord-005646-xhx9pzhj 3982 7 I.tmol/I I.tmol/I NNP cord-005646-xhx9pzhj 3982 8 in in IN cord-005646-xhx9pzhj 3982 9 mothers mother NNS cord-005646-xhx9pzhj 3982 10 milk milk NN cord-005646-xhx9pzhj 3982 11 delivered deliver VBD cord-005646-xhx9pzhj 3982 12 eutrophic eutrophic JJ cord-005646-xhx9pzhj 3982 13 babies baby NNS cord-005646-xhx9pzhj 3982 14 , , , cord-005646-xhx9pzhj 3982 15 and and CC cord-005646-xhx9pzhj 3982 16 singnificant singnificant VBP cord-005646-xhx9pzhj 3982 17 higher high JJR cord-005646-xhx9pzhj 3982 18 mean mean JJ cord-005646-xhx9pzhj 3982 19 coenetration coenetration NN cord-005646-xhx9pzhj 3982 20 113,88 113,88 CD cord-005646-xhx9pzhj 3982 21 l.tmol/I l.tmol/I NNP cord-005646-xhx9pzhj 3982 22 , , , cord-005646-xhx9pzhj 3982 23 of of IN cord-005646-xhx9pzhj 3982 24 hypotrophic hypotrophic JJ cord-005646-xhx9pzhj 3982 25 premature premature JJ cord-005646-xhx9pzhj 3982 26 infants infant NNS cord-005646-xhx9pzhj 3982 27 ( ( -LRB- cord-005646-xhx9pzhj 3982 28 p<0,05 p<0,05 NNP cord-005646-xhx9pzhj 3982 29 ) ) -RRB- cord-005646-xhx9pzhj 3982 30 . . . cord-005646-xhx9pzhj 3983 1 Breast breast NN cord-005646-xhx9pzhj 3983 2 milk milk NN cord-005646-xhx9pzhj 3983 3 earnitine earnitine NN cord-005646-xhx9pzhj 3983 4 concentration concentration NN cord-005646-xhx9pzhj 3983 5 was be VBD cord-005646-xhx9pzhj 3983 6 ranged range VBN cord-005646-xhx9pzhj 3983 7 between between IN cord-005646-xhx9pzhj 3983 8 39,15 39,15 CD cord-005646-xhx9pzhj 3983 9 - - HYPH cord-005646-xhx9pzhj 3983 10 163,71 163,71 NNP cord-005646-xhx9pzhj 3983 11 ~moI,'l ~moi,'l CD cord-005646-xhx9pzhj 3983 12 , , , cord-005646-xhx9pzhj 3983 13 and and CC cord-005646-xhx9pzhj 3983 14 daily daily JJ cord-005646-xhx9pzhj 3983 15 carnitine carnitine NN cord-005646-xhx9pzhj 3983 16 excretion excretion NN cord-005646-xhx9pzhj 3983 17 was be VBD cord-005646-xhx9pzhj 3983 18 between between IN cord-005646-xhx9pzhj 3983 19 9,7 9,7 CD cord-005646-xhx9pzhj 3983 20 - - SYM cord-005646-xhx9pzhj 3983 21 165,48 165,48 NNP cord-005646-xhx9pzhj 3983 22 p.mol/I p.mol/i NN cord-005646-xhx9pzhj 3983 23 , , , cord-005646-xhx9pzhj 3984 1 mean mean VB cord-005646-xhx9pzhj 3985 1 60,6 60,6 CD cord-005646-xhx9pzhj 3985 2 + + CC cord-005646-xhx9pzhj 3986 1 -38,7I -38,7i UH cord-005646-xhx9pzhj 3986 2 p.molll p.molll ADD cord-005646-xhx9pzhj 3986 3 . . . cord-005646-xhx9pzhj 3987 1 The the DT cord-005646-xhx9pzhj 3987 2 daily daily JJ cord-005646-xhx9pzhj 3987 3 mean mean JJ cord-005646-xhx9pzhj 3987 4 carnitine carnitine NN cord-005646-xhx9pzhj 3987 5 intake intake NN cord-005646-xhx9pzhj 3987 6 was be VBD cord-005646-xhx9pzhj 3987 7 from from IN cord-005646-xhx9pzhj 3987 8 1 1 CD cord-005646-xhx9pzhj 3987 9 - - HYPH cord-005646-xhx9pzhj 3987 10 1,93 1,93 CD cord-005646-xhx9pzhj 3988 1 mgkg mgkg NNP cord-005646-xhx9pzhj 3988 2 / / SYM cord-005646-xhx9pzhj 3988 3 d d NNP cord-005646-xhx9pzhj 3988 4 , , , cord-005646-xhx9pzhj 3988 5 in in IN cord-005646-xhx9pzhj 3988 6 eutrophic eutrophic JJ cord-005646-xhx9pzhj 3988 7 and and CC cord-005646-xhx9pzhj 3988 8 1,23 1,23 CD cord-005646-xhx9pzhj 3988 9 - - HYPH cord-005646-xhx9pzhj 3988 10 1,93 1,93 CD cord-005646-xhx9pzhj 3989 1 mg mg NNP cord-005646-xhx9pzhj 3989 2 / / SYM cord-005646-xhx9pzhj 3989 3 kg kg NNP cord-005646-xhx9pzhj 3989 4 / / SYM cord-005646-xhx9pzhj 3989 5 d d XX cord-005646-xhx9pzhj 3989 6 , , , cord-005646-xhx9pzhj 3989 7 in in IN cord-005646-xhx9pzhj 3989 8 hypotrophic hypotrophic JJ cord-005646-xhx9pzhj 3989 9 premature premature JJ cord-005646-xhx9pzhj 3989 10 infants infant NNS cord-005646-xhx9pzhj 3989 11 , , , cord-005646-xhx9pzhj 3989 12 in in IN cord-005646-xhx9pzhj 3989 13 milk milk NN cord-005646-xhx9pzhj 3989 14 volumene volumene NN cord-005646-xhx9pzhj 3989 15 intake intake NN cord-005646-xhx9pzhj 3989 16 from from IN cord-005646-xhx9pzhj 3989 17 150 150 CD cord-005646-xhx9pzhj 3989 18 - - HYPH cord-005646-xhx9pzhj 3989 19 200 200 CD cord-005646-xhx9pzhj 3989 20 mllkgld mllkgld NNS cord-005646-xhx9pzhj 3989 21 . . . cord-005646-xhx9pzhj 3990 1 , , , cord-005646-xhx9pzhj 3990 2 The the DT cord-005646-xhx9pzhj 3990 3 results result NNS cord-005646-xhx9pzhj 3990 4 of of IN cord-005646-xhx9pzhj 3990 5 this this DT cord-005646-xhx9pzhj 3990 6 study study NN cord-005646-xhx9pzhj 3990 7 suggest suggest VBP cord-005646-xhx9pzhj 3990 8 that that IN cord-005646-xhx9pzhj 3990 9 premature premature JJ cord-005646-xhx9pzhj 3990 10 infants infant NNS cord-005646-xhx9pzhj 3990 11 should should MD cord-005646-xhx9pzhj 3990 12 be be VB cord-005646-xhx9pzhj 3990 13 fed feed VBN cord-005646-xhx9pzhj 3990 14 with with IN cord-005646-xhx9pzhj 3990 15 own own JJ cord-005646-xhx9pzhj 3990 16 mothers mother NNS cord-005646-xhx9pzhj 3990 17 mitk mitk NNP cord-005646-xhx9pzhj 3990 18 in in IN cord-005646-xhx9pzhj 3990 19 eady eady NNP cord-005646-xhx9pzhj 3990 20 neonatal neonatal JJ cord-005646-xhx9pzhj 3990 21 pedod pedod NN cord-005646-xhx9pzhj 3990 22 in in IN cord-005646-xhx9pzhj 3990 23 attempt attempt NN cord-005646-xhx9pzhj 3990 24 to to TO cord-005646-xhx9pzhj 3990 25 prevent prevent VB cord-005646-xhx9pzhj 3990 26 camitine camitine NN cord-005646-xhx9pzhj 3990 27 deficiency deficiency NN cord-005646-xhx9pzhj 3990 28 . . . cord-005646-xhx9pzhj 3991 1 KETO KETO NNP cord-005646-xhx9pzhj 3991 2 - - HYPH cord-005646-xhx9pzhj 3991 3 ACIDS ACIDS NNPS cord-005646-xhx9pzhj 3991 4 AND and CC cord-005646-xhx9pzhj 3991 5 PARENTERAL parenteral JJ cord-005646-xhx9pzhj 3991 6 LIPID lipid NN cord-005646-xhx9pzhj 3991 7 ADMLNISTRATION ADMLNISTRATION NNP cord-005646-xhx9pzhj 3991 8 . . . cord-005646-xhx9pzhj 3992 1 Castorina Castorina NNP cord-005646-xhx9pzhj 3992 2 M. M. NNP cord-005646-xhx9pzhj 3992 3 , , , cord-005646-xhx9pzhj 3992 4 Antuzzi Antuzzi NNP cord-005646-xhx9pzhj 3992 5 D. D. NNP cord-005646-xhx9pzhj 3992 6 , , , cord-005646-xhx9pzhj 3992 7 Ricci Ricci NNP cord-005646-xhx9pzhj 3992 8 R. R. NNP cord-005646-xhx9pzhj 3992 9 , , , cord-005646-xhx9pzhj 3992 10 Rendeli Rendeli NNP cord-005646-xhx9pzhj 3992 11 C. C. NNP cord-005646-xhx9pzhj 3992 12 , , , cord-005646-xhx9pzhj 3993 1 Polidori Polidori NNP cord-005646-xhx9pzhj 3993 2 G. G. NNP cord-005646-xhx9pzhj 3993 3 Pediatric Pediatric NNP cord-005646-xhx9pzhj 3993 4 Intensive Intensive NNP cord-005646-xhx9pzhj 3993 5 Care Care NNP cord-005646-xhx9pzhj 3993 6 Unit Unit NNP cord-005646-xhx9pzhj 3994 1 -Catholic -Catholic . cord-005646-xhx9pzhj 3995 1 University University NNP cord-005646-xhx9pzhj 3995 2 -Roma -Roma NNP cord-005646-xhx9pzhj 3996 1 ( ( -LRB- cord-005646-xhx9pzhj 3996 2 Italy Italy NNP cord-005646-xhx9pzhj 3996 3 ) ) -RRB- cord-005646-xhx9pzhj 3996 4 . . . cord-005646-xhx9pzhj 3997 1 Some some DT cord-005646-xhx9pzhj 3997 2 metabolic metabolic JJ cord-005646-xhx9pzhj 3997 3 studies study NNS cord-005646-xhx9pzhj 3997 4 have have VBP cord-005646-xhx9pzhj 3997 5 suggested suggest VBN cord-005646-xhx9pzhj 3997 6 that that IN cord-005646-xhx9pzhj 3997 7 the the DT cord-005646-xhx9pzhj 3997 8 administration administration NN cord-005646-xhx9pzhj 3997 9 of of IN cord-005646-xhx9pzhj 3997 10 mediumchain mediumchain NNP cord-005646-xhx9pzhj 3997 11 tlTgticerides tlTgticerides NNP cord-005646-xhx9pzhj 3997 12 ( ( -LRB- cord-005646-xhx9pzhj 3997 13 MCT MCT NNP cord-005646-xhx9pzhj 3997 14 ) ) -RRB- cord-005646-xhx9pzhj 3997 15 might may MD cord-005646-xhx9pzhj 3997 16 induce induce VB cord-005646-xhx9pzhj 3997 17 a a DT cord-005646-xhx9pzhj 3997 18 marked marked JJ cord-005646-xhx9pzhj 3997 19 increase increase NN cord-005646-xhx9pzhj 3997 20 in in IN cord-005646-xhx9pzhj 3997 21 ketone ketone NN cord-005646-xhx9pzhj 3997 22 body body NN cord-005646-xhx9pzhj 3997 23 concentrations concentration NNS cord-005646-xhx9pzhj 3997 24 ; ; : cord-005646-xhx9pzhj 3997 25 the the DT cord-005646-xhx9pzhj 3997 26 aim aim NN cord-005646-xhx9pzhj 3997 27 of of IN cord-005646-xhx9pzhj 3997 28 this this DT cord-005646-xhx9pzhj 3997 29 study study NN cord-005646-xhx9pzhj 3997 30 is be VBZ cord-005646-xhx9pzhj 3997 31 to to TO cord-005646-xhx9pzhj 3997 32 evaluate evaluate VB cord-005646-xhx9pzhj 3997 33 the the DT cord-005646-xhx9pzhj 3997 34 effective effective JJ cord-005646-xhx9pzhj 3997 35 ketogenetic ketogenetic JJ cord-005646-xhx9pzhj 3997 36 risk risk NN cord-005646-xhx9pzhj 3997 37 of of IN cord-005646-xhx9pzhj 3997 38 infusing infuse VBG cord-005646-xhx9pzhj 3997 39 MCT MCT NNP cord-005646-xhx9pzhj 3997 40 emulsions emulsion NNS cord-005646-xhx9pzhj 3997 41 in in IN cord-005646-xhx9pzhj 3997 42 total total JJ cord-005646-xhx9pzhj 3997 43 parenteral parenteral JJ cord-005646-xhx9pzhj 3997 44 nutrition nutrition NN cord-005646-xhx9pzhj 3997 45 ( ( -LRB- cord-005646-xhx9pzhj 3997 46 TPN TPN NNP cord-005646-xhx9pzhj 3997 47 ) ) -RRB- cord-005646-xhx9pzhj 3997 48 . . . cord-005646-xhx9pzhj 3998 1 Two two CD cord-005646-xhx9pzhj 3998 2 groups group NNS cord-005646-xhx9pzhj 3998 3 of of IN cord-005646-xhx9pzhj 3998 4 seriously seriously RB cord-005646-xhx9pzhj 3998 5 infected infect VBN cord-005646-xhx9pzhj 3998 6 children child NNS cord-005646-xhx9pzhj 3998 7 were be VBD cord-005646-xhx9pzhj 3998 8 examined examine VBN cord-005646-xhx9pzhj 3998 9 : : : cord-005646-xhx9pzhj 3998 10 A-12 a-12 NN cord-005646-xhx9pzhj 3998 11 septic septic JJ cord-005646-xhx9pzhj 3998 12 infants infant NNS cord-005646-xhx9pzhj 3998 13 were be VBD cord-005646-xhx9pzhj 3998 14 given give VBN cord-005646-xhx9pzhj 3998 15 to to IN cord-005646-xhx9pzhj 3998 16 TPN TPN NNP cord-005646-xhx9pzhj 3998 17 with with IN cord-005646-xhx9pzhj 3998 18 a a DT cord-005646-xhx9pzhj 3998 19 100 100 CD cord-005646-xhx9pzhj 3998 20 % % NN cord-005646-xhx9pzhj 3998 21 of of IN cord-005646-xhx9pzhj 3998 22 long long JJ cord-005646-xhx9pzhj 3998 23 - - HYPH cord-005646-xhx9pzhj 3998 24 chain chain NN cord-005646-xhx9pzhj 3998 25 tryglicerides trygliceride NNS cord-005646-xhx9pzhj 3998 26 ( ( -LRB- cord-005646-xhx9pzhj 3998 27 100 100 CD cord-005646-xhx9pzhj 3998 28 LCT LCT NNP cord-005646-xhx9pzhj 3998 29 ) ) -RRB- cord-005646-xhx9pzhj 3998 30 . . . cord-005646-xhx9pzhj 3999 1 B-10 b-10 NN cord-005646-xhx9pzhj 3999 2 septic septic JJ cord-005646-xhx9pzhj 3999 3 infants infant NNS cord-005646-xhx9pzhj 3999 4 , , , cord-005646-xhx9pzhj 3999 5 in in IN cord-005646-xhx9pzhj 3999 6 wich wich RB cord-005646-xhx9pzhj 3999 7 the the DT cord-005646-xhx9pzhj 3999 8 lipid lipid NN cord-005646-xhx9pzhj 3999 9 source source NN cord-005646-xhx9pzhj 3999 10 in in IN cord-005646-xhx9pzhj 3999 11 TPN TPN NNP cord-005646-xhx9pzhj 3999 12 consisted consist VBD cord-005646-xhx9pzhj 3999 13 in in IN cord-005646-xhx9pzhj 3999 14 a a DT cord-005646-xhx9pzhj 3999 15 50 50 CD cord-005646-xhx9pzhj 3999 16 - - SYM cord-005646-xhx9pzhj 3999 17 50 50 CD cord-005646-xhx9pzhj 3999 18 mixture mixture NN cord-005646-xhx9pzhj 3999 19 of of IN cord-005646-xhx9pzhj 3999 20 LCT LCT NNP cord-005646-xhx9pzhj 3999 21 and and CC cord-005646-xhx9pzhj 3999 22 MCT MCT NNP cord-005646-xhx9pzhj 3999 23 . . . cord-005646-xhx9pzhj 4000 1 The the DT cord-005646-xhx9pzhj 4000 2 children child NNS cord-005646-xhx9pzhj 4000 3 in in IN cord-005646-xhx9pzhj 4000 4 the the DT cord-005646-xhx9pzhj 4000 5 different different JJ cord-005646-xhx9pzhj 4000 6 groups group NNS cord-005646-xhx9pzhj 4000 7 showed show VBD cord-005646-xhx9pzhj 4000 8 similar similar JJ cord-005646-xhx9pzhj 4000 9 severity severity NN cord-005646-xhx9pzhj 4000 10 and and CC cord-005646-xhx9pzhj 4000 11 therapeutic therapeutic JJ cord-005646-xhx9pzhj 4000 12 scores score NNS cord-005646-xhx9pzhj 4000 13 ( ( -LRB- cord-005646-xhx9pzhj 4000 14 PRISM PRISM NNP cord-005646-xhx9pzhj 4000 15 , , , cord-005646-xhx9pzhj 4000 16 TISS TISS NNP cord-005646-xhx9pzhj 4000 17 , , , cord-005646-xhx9pzhj 4000 18 ~ ~ NFP cord-005646-xhx9pzhj 4000 19 , , , cord-005646-xhx9pzhj 4000 20 f~2 f~2 NNP cord-005646-xhx9pzhj 4000 21 , , , cord-005646-xhx9pzhj 4000 22 f~3 f~3 NNP cord-005646-xhx9pzhj 4000 23 ) ) -RRB- cord-005646-xhx9pzhj 4000 24 ; ; : cord-005646-xhx9pzhj 4000 25 the the DT cord-005646-xhx9pzhj 4000 26 lipid lipid NN cord-005646-xhx9pzhj 4000 27 intake intake NN cord-005646-xhx9pzhj 4000 28 was be VBD cord-005646-xhx9pzhj 4000 29 the the DT cord-005646-xhx9pzhj 4000 30 same same JJ cord-005646-xhx9pzhj 4000 31 , , , cord-005646-xhx9pzhj 4000 32 corresponding correspond VBG cord-005646-xhx9pzhj 4000 33 to to IN cord-005646-xhx9pzhj 4000 34 1 1 CD cord-005646-xhx9pzhj 4000 35 - - SYM cord-005646-xhx9pzhj 4000 36 1.5 1.5 CD cord-005646-xhx9pzhj 4000 37 g g NN cord-005646-xhx9pzhj 4000 38 , , , cord-005646-xhx9pzhj 4000 39 CKg CKg NNP cord-005646-xhx9pzhj 4000 40 bodyweight bodyweight NN cord-005646-xhx9pzhj 4000 41 / / SYM cord-005646-xhx9pzhj 4000 42 day day NN cord-005646-xhx9pzhj 4000 43 . . . cord-005646-xhx9pzhj 4001 1 In in IN cord-005646-xhx9pzhj 4001 2 all all DT cord-005646-xhx9pzhj 4001 3 patients patient NNS cord-005646-xhx9pzhj 4001 4 a a DT cord-005646-xhx9pzhj 4001 5 sample sample NN cord-005646-xhx9pzhj 4001 6 of of IN cord-005646-xhx9pzhj 4001 7 urine urine NN cord-005646-xhx9pzhj 4001 8 was be VBD cord-005646-xhx9pzhj 4001 9 taken take VBN cord-005646-xhx9pzhj 4001 10 six six CD cord-005646-xhx9pzhj 4001 11 times time NNS cord-005646-xhx9pzhj 4001 12 a a DT cord-005646-xhx9pzhj 4001 13 day day NN cord-005646-xhx9pzhj 4001 14 for for IN cord-005646-xhx9pzhj 4001 15 the the DT cord-005646-xhx9pzhj 4001 16 whole whole JJ cord-005646-xhx9pzhj 4001 17 time time NN cord-005646-xhx9pzhj 4001 18 of of IN cord-005646-xhx9pzhj 4001 19 TPN TPN NNP cord-005646-xhx9pzhj 4002 1 The the DT cord-005646-xhx9pzhj 4002 2 urine urine NN cord-005646-xhx9pzhj 4002 3 samples sample NNS cord-005646-xhx9pzhj 4002 4 were be VBD cord-005646-xhx9pzhj 4002 5 screened screen VBN cord-005646-xhx9pzhj 4002 6 by by IN cord-005646-xhx9pzhj 4002 7 the the DT cord-005646-xhx9pzhj 4002 8 diphenylhydrazone diphenylhydrazone NN cord-005646-xhx9pzhj 4002 9 test test NN cord-005646-xhx9pzhj 4002 10 , , , cord-005646-xhx9pzhj 4002 11 and and CC cord-005646-xhx9pzhj 4002 12 the the DT cord-005646-xhx9pzhj 4002 13 ketoacids ketoacids NNP cord-005646-xhx9pzhj 4002 14 excretion excretion NN cord-005646-xhx9pzhj 4002 15 was be VBD cord-005646-xhx9pzhj 4002 16 confirmed confirm VBN cord-005646-xhx9pzhj 4002 17 by by IN cord-005646-xhx9pzhj 4002 18 a a DT cord-005646-xhx9pzhj 4002 19 chromatography chromatography NN cord-005646-xhx9pzhj 4002 20 . . . cord-005646-xhx9pzhj 4003 1 The the DT cord-005646-xhx9pzhj 4003 2 urinary urinary JJ cord-005646-xhx9pzhj 4003 3 excretion excretion NN cord-005646-xhx9pzhj 4003 4 of of IN cord-005646-xhx9pzhj 4003 5 13-keto 13-keto CD cord-005646-xhx9pzhj 4003 6 - - HYPH cord-005646-xhx9pzhj 4003 7 acids acid NNS cord-005646-xhx9pzhj 4003 8 equivalent equivalent JJ cord-005646-xhx9pzhj 4003 9 to to IN cord-005646-xhx9pzhj 4003 10 p p NN cord-005646-xhx9pzhj 4003 11 - - HYPH cord-005646-xhx9pzhj 4003 12 OHphenyl OHphenyl NNP cord-005646-xhx9pzhj 4003 13 - - HYPH cord-005646-xhx9pzhj 4003 14 pymvate pymvate NNP cord-005646-xhx9pzhj 4003 15 ( ( -LRB- cord-005646-xhx9pzhj 4003 16 mcg mcg NNP cord-005646-xhx9pzhj 4003 17 / / SYM cord-005646-xhx9pzhj 4003 18 ml ml NN cord-005646-xhx9pzhj 4003 19 urine urine NN cord-005646-xhx9pzhj 4003 20 ) ) -RRB- cord-005646-xhx9pzhj 4003 21 is be VBZ cord-005646-xhx9pzhj 4003 22 summarized summarize VBN cord-005646-xhx9pzhj 4003 23 in in IN cord-005646-xhx9pzhj 4003 24 the the DT cord-005646-xhx9pzhj 4003 25 No no DT cord-005646-xhx9pzhj 4003 26 significant significant JJ cord-005646-xhx9pzhj 4003 27 increases increase NNS cord-005646-xhx9pzhj 4003 28 in in IN cord-005646-xhx9pzhj 4003 29 frequence frequence NNP cord-005646-xhx9pzhj 4003 30 and/or and/or CC cord-005646-xhx9pzhj 4003 31 in in IN cord-005646-xhx9pzhj 4003 32 severity severity NN cord-005646-xhx9pzhj 4003 33 of of IN cord-005646-xhx9pzhj 4003 34 Acid Acid NNP cord-005646-xhx9pzhj 4003 35 - - HYPH cord-005646-xhx9pzhj 4003 36 Base Base NNP cord-005646-xhx9pzhj 4003 37 Disturbances Disturbances NNPS cord-005646-xhx9pzhj 4003 38 were be VBD cord-005646-xhx9pzhj 4003 39 found find VBN cord-005646-xhx9pzhj 4003 40 in in IN cord-005646-xhx9pzhj 4003 41 all all DT cord-005646-xhx9pzhj 4003 42 studied study VBN cord-005646-xhx9pzhj 4003 43 patients patient NNS cord-005646-xhx9pzhj 4003 44 in in IN cord-005646-xhx9pzhj 4003 45 consequence consequence NN cord-005646-xhx9pzhj 4003 46 of of IN cord-005646-xhx9pzhj 4003 47 the the DT cord-005646-xhx9pzhj 4003 48 lipid lipid NN cord-005646-xhx9pzhj 4003 49 infusion infusion NN cord-005646-xhx9pzhj 4003 50 . . . cord-005646-xhx9pzhj 4004 1 The the DT cord-005646-xhx9pzhj 4004 2 patients patient NNS cord-005646-xhx9pzhj 4004 3 of of IN cord-005646-xhx9pzhj 4004 4 B b NN cord-005646-xhx9pzhj 4004 5 - - HYPH cord-005646-xhx9pzhj 4004 6 group group NN cord-005646-xhx9pzhj 4004 7 showed show VBD cord-005646-xhx9pzhj 4004 8 a a DT cord-005646-xhx9pzhj 4004 9 lower low JJR cord-005646-xhx9pzhj 4004 10 excretion excretion NN cord-005646-xhx9pzhj 4004 11 of of IN cord-005646-xhx9pzhj 4004 12 13-ketoacids 13-ketoacids CD cord-005646-xhx9pzhj 4004 13 . . . cord-005646-xhx9pzhj 4005 1 The the DT cord-005646-xhx9pzhj 4005 2 c~-keto c~-keto NN cord-005646-xhx9pzhj 4005 3 - - HYPH cord-005646-xhx9pzhj 4005 4 acids acid NNS cord-005646-xhx9pzhj 4005 5 excretion excretion NN cord-005646-xhx9pzhj 4005 6 was be VBD cord-005646-xhx9pzhj 4005 7 ever ever RB cord-005646-xhx9pzhj 4005 8 unsignificant unsignificant JJ cord-005646-xhx9pzhj 4005 9 and and CC cord-005646-xhx9pzhj 4005 10 seemed seem VBD cord-005646-xhx9pzhj 4005 11 to to TO cord-005646-xhx9pzhj 4005 12 be be VB cord-005646-xhx9pzhj 4005 13 correlated correlate VBN cord-005646-xhx9pzhj 4005 14 with with IN cord-005646-xhx9pzhj 4005 15 the the DT cord-005646-xhx9pzhj 4005 16 illness illness NN cord-005646-xhx9pzhj 4005 17 severity severity NN cord-005646-xhx9pzhj 4005 18 more more JJR cord-005646-xhx9pzhj 4005 19 than than IN cord-005646-xhx9pzhj 4005 20 with with IN cord-005646-xhx9pzhj 4005 21 the the DT cord-005646-xhx9pzhj 4005 22 lenght lenght NN cord-005646-xhx9pzhj 4005 23 of of IN cord-005646-xhx9pzhj 4005 24 the the DT cord-005646-xhx9pzhj 4005 25 tryglicerides tryglicerides NNP cord-005646-xhx9pzhj 4005 26 chain chain NN cord-005646-xhx9pzhj 4005 27 . . . cord-005646-xhx9pzhj 4006 1 This this DT cord-005646-xhx9pzhj 4006 2 observations observation NNS cord-005646-xhx9pzhj 4006 3 let let VBD cord-005646-xhx9pzhj 4006 4 us -PRON- PRP cord-005646-xhx9pzhj 4006 5 suppose suppose VB cord-005646-xhx9pzhj 4006 6 that that IN cord-005646-xhx9pzhj 4006 7 the the DT cord-005646-xhx9pzhj 4006 8 MCT MCT NNP cord-005646-xhx9pzhj 4006 9 , , , cord-005646-xhx9pzhj 4006 10 at at IN cord-005646-xhx9pzhj 4006 11 employed employ VBN cord-005646-xhx9pzhj 4006 12 doses dose NNS cord-005646-xhx9pzhj 4006 13 , , , cord-005646-xhx9pzhj 4006 14 can can MD cord-005646-xhx9pzhj 4006 15 be be VB cord-005646-xhx9pzhj 4006 16 safely safely RB cord-005646-xhx9pzhj 4006 17 administred administre VBN cord-005646-xhx9pzhj 4006 18 also also RB cord-005646-xhx9pzhj 4006 19 in in IN cord-005646-xhx9pzhj 4006 20 childen childen NNS cord-005646-xhx9pzhj 4006 21 with with IN cord-005646-xhx9pzhj 4006 22 metabolic metabolic JJ cord-005646-xhx9pzhj 4006 23 acidosis acidosis NN cord-005646-xhx9pzhj 4007 1 and/or and/or CC cord-005646-xhx9pzhj 4007 2 serious serious JJ cord-005646-xhx9pzhj 4007 3 illness illness NN cord-005646-xhx9pzhj 4007 4 . . . cord-005646-xhx9pzhj 4008 1 REYE REYE NNP cord-005646-xhx9pzhj 4008 2 SYNDROME SYNDROME NNP cord-005646-xhx9pzhj 4008 3 Cayetano Cayetano NNP cord-005646-xhx9pzhj 4008 4 Heredia Heredia NNP cord-005646-xhx9pzhj 4008 5 Hospital Hospital NNP cord-005646-xhx9pzhj 4008 6 , , , cord-005646-xhx9pzhj 4008 7 Lima Lima NNP cord-005646-xhx9pzhj 4008 8 , , , cord-005646-xhx9pzhj 4008 9 Peru Peru NNP cord-005646-xhx9pzhj 4008 10 Five five CD cord-005646-xhx9pzhj 4008 11 patients patient NNS cord-005646-xhx9pzhj 4008 12 with with IN cord-005646-xhx9pzhj 4008 13 Reye Reye NNP cord-005646-xhx9pzhj 4008 14 syndrome syndrome NN cord-005646-xhx9pzhj 4008 15 were be VBD cord-005646-xhx9pzhj 4008 16 studied study VBN cord-005646-xhx9pzhj 4008 17 ; ; : cord-005646-xhx9pzhj 4008 18 included include VBN cord-005646-xhx9pzhj 4008 19 were be VBD cord-005646-xhx9pzhj 4008 20 those those DT cord-005646-xhx9pzhj 4008 21 diagnosed diagnose VBN cord-005646-xhx9pzhj 4008 22 from from IN cord-005646-xhx9pzhj 4008 23 January January NNP cord-005646-xhx9pzhj 4008 24 1991 1991 CD cord-005646-xhx9pzhj 4008 25 to to IN cord-005646-xhx9pzhj 4008 26 March March NNP cord-005646-xhx9pzhj 4008 27 1994 1994 CD cord-005646-xhx9pzhj 4008 28 and and CC cord-005646-xhx9pzhj 4008 29 treated treat VBN cord-005646-xhx9pzhj 4008 30 at at IN cord-005646-xhx9pzhj 4008 31 Cayetano Cayetano NNP cord-005646-xhx9pzhj 4008 32 Heredia Heredia NNP cord-005646-xhx9pzhj 4008 33 Hospital Hospital NNP cord-005646-xhx9pzhj 4008 34 . . . cord-005646-xhx9pzhj 4009 1 The the DT cord-005646-xhx9pzhj 4009 2 age age NN cord-005646-xhx9pzhj 4009 3 of of IN cord-005646-xhx9pzhj 4009 4 presentation presentation NN cord-005646-xhx9pzhj 4009 5 varied vary VBN cord-005646-xhx9pzhj 4009 6 from from IN cord-005646-xhx9pzhj 4009 7 z.5 z.5 CD cord-005646-xhx9pzhj 4009 8 to to IN cord-005646-xhx9pzhj 4009 9 7 7 CD cord-005646-xhx9pzhj 4009 10 months month NNS cord-005646-xhx9pzhj 4009 11 . . . cord-005646-xhx9pzhj 4010 1 The the DT cord-005646-xhx9pzhj 4010 2 syndrome syndrome NN cord-005646-xhx9pzhj 4010 3 occurred occur VBD cord-005646-xhx9pzhj 4010 4 more more RBR cord-005646-xhx9pzhj 4010 5 frequently frequently RB cord-005646-xhx9pzhj 4010 6 in in IN cord-005646-xhx9pzhj 4010 7 males male NNS cord-005646-xhx9pzhj 4010 8 ( ( -LRB- cord-005646-xhx9pzhj 4010 9 4/5 4/5 CD cord-005646-xhx9pzhj 4010 10 ) ) -RRB- cord-005646-xhx9pzhj 4010 11 ; ; : cord-005646-xhx9pzhj 4010 12 the the DT cord-005646-xhx9pzhj 4010 13 time time NN cord-005646-xhx9pzhj 4010 14 of of IN cord-005646-xhx9pzhj 4010 15 illness illness NN cord-005646-xhx9pzhj 4010 16 at at IN cord-005646-xhx9pzhj 4010 17 the the DT cord-005646-xhx9pzhj 4010 18 presentation presentation NN cord-005646-xhx9pzhj 4010 19 varied vary VBN cord-005646-xhx9pzhj 4010 20 from from IN cord-005646-xhx9pzhj 4010 21 2 2 CD cord-005646-xhx9pzhj 4010 22 to to IN cord-005646-xhx9pzhj 4010 23 lo lo NNP cord-005646-xhx9pzhj 4010 24 days day NNS cord-005646-xhx9pzhj 4010 25 , , , cord-005646-xhx9pzhj 4010 26 and and CC cord-005646-xhx9pzhj 4010 27 the the DT cord-005646-xhx9pzhj 4010 28 following following JJ cord-005646-xhx9pzhj 4010 29 features feature NNS cord-005646-xhx9pzhj 4010 30 were be VBD cord-005646-xhx9pzhj 4010 31 found find VBN cord-005646-xhx9pzhj 4010 32 : : : cord-005646-xhx9pzhj 4010 33 fever fever NN cord-005646-xhx9pzhj 4010 34 ( ( -LRB- cord-005646-xhx9pzhj 4010 35 3/5 3/5 CD cord-005646-xhx9pzhj 4010 36 ) ) -RRB- cord-005646-xhx9pzhj 4010 37 , , , cord-005646-xhx9pzhj 4010 38 akeration akeration NN cord-005646-xhx9pzhj 4010 39 in in IN cord-005646-xhx9pzhj 4010 40 mental mental JJ cord-005646-xhx9pzhj 4010 41 status status NN cord-005646-xhx9pzhj 4010 42 ( ( -LRB- cord-005646-xhx9pzhj 4010 43 5/5 5/5 CD cord-005646-xhx9pzhj 4010 44 ) ) -RRB- cord-005646-xhx9pzhj 4010 45 , , , cord-005646-xhx9pzhj 4010 46 seizures seizure NNS cord-005646-xhx9pzhj 4010 47 ( ( -LRB- cord-005646-xhx9pzhj 4010 48 4/5 4/5 CD cord-005646-xhx9pzhj 4010 49 ) ) -RRB- cord-005646-xhx9pzhj 4010 50 , , , cord-005646-xhx9pzhj 4010 51 gastrointestinal gastrointestinal JJ cord-005646-xhx9pzhj 4010 52 illnesses illness NNS cord-005646-xhx9pzhj 4010 53 ( ( -LRB- cord-005646-xhx9pzhj 4010 54 diarrhea diarrhea NN cord-005646-xhx9pzhj 4010 55 ) ) -RRB- cord-005646-xhx9pzhj 4010 56 ( ( -LRB- cord-005646-xhx9pzhj 4010 57 4/5 4/5 CD cord-005646-xhx9pzhj 4010 58 ) ) -RRB- cord-005646-xhx9pzhj 4010 59 , , , cord-005646-xhx9pzhj 4010 60 and and CC cord-005646-xhx9pzhj 4010 61 respiratory respiratory JJ cord-005646-xhx9pzhj 4010 62 insufficiency insufficiency NN cord-005646-xhx9pzhj 4010 63 ( ( -LRB- cord-005646-xhx9pzhj 4010 64 1/5 1/5 CD cord-005646-xhx9pzhj 4010 65 ) ) -RRB- cord-005646-xhx9pzhj 4011 1 --in --in NNP cord-005646-xhx9pzhj 4012 1 this this DT cord-005646-xhx9pzhj 4012 2 case case NN cord-005646-xhx9pzhj 4012 3 ventilator)-support ventilator)-support NNP cord-005646-xhx9pzhj 4012 4 was be VBD cord-005646-xhx9pzhj 4012 5 needed need VBN cord-005646-xhx9pzhj 4012 6 , , , cord-005646-xhx9pzhj 4012 7 In in IN cord-005646-xhx9pzhj 4012 8 all all DT cord-005646-xhx9pzhj 4012 9 cases case NNS cord-005646-xhx9pzhj 4012 10 hepatomegaly hepatomegaly NNP cord-005646-xhx9pzhj 4012 11 , , , cord-005646-xhx9pzhj 4012 12 intracranial intracranial JJ cord-005646-xhx9pzhj 4012 13 hypertension hypertension NN cord-005646-xhx9pzhj 4012 14 , , , cord-005646-xhx9pzhj 4012 15 hypokalemia hypokalemia NN cord-005646-xhx9pzhj 4012 16 hyponatremia hyponatremia NN cord-005646-xhx9pzhj 4012 17 , , , cord-005646-xhx9pzhj 4012 18 metabolic metabolic JJ cord-005646-xhx9pzhj 4012 19 acidosis acidosis NN cord-005646-xhx9pzhj 4012 20 , , , cord-005646-xhx9pzhj 4012 21 hyperammonemia hyperammonemia NN cord-005646-xhx9pzhj 4012 22 and and CC cord-005646-xhx9pzhj 4012 23 elevation elevation NN cord-005646-xhx9pzhj 4012 24 of of IN cord-005646-xhx9pzhj 4012 25 hepatic hepatic JJ cord-005646-xhx9pzhj 4012 26 enzymes enzyme NNS cord-005646-xhx9pzhj 4012 27 were be VBD cord-005646-xhx9pzhj 4012 28 found find VBN cord-005646-xhx9pzhj 4012 29 . . . cord-005646-xhx9pzhj 4013 1 Coagulation coagulation NN cord-005646-xhx9pzhj 4013 2 blood blood NN cord-005646-xhx9pzhj 4013 3 tests test NNS cord-005646-xhx9pzhj 4013 4 were be VBD cord-005646-xhx9pzhj 4013 5 abnormal abnormal JJ cord-005646-xhx9pzhj 4013 6 in in IN cord-005646-xhx9pzhj 4013 7 three three CD cord-005646-xhx9pzhj 4013 8 patients patient NNS cord-005646-xhx9pzhj 4013 9 . . . cord-005646-xhx9pzhj 4014 1 Cerebrospinal cerebrospinal NN cord-005646-xhx9pzhj 4014 2 fluid fluid NN cord-005646-xhx9pzhj 4014 3 ( ( -LRB- cord-005646-xhx9pzhj 4014 4 CSF CSF NNP cord-005646-xhx9pzhj 4014 5 ) ) -RRB- cord-005646-xhx9pzhj 4014 6 showed show VBD cord-005646-xhx9pzhj 4014 7 hypocellularity hypocellularity NN cord-005646-xhx9pzhj 4014 8 in in IN cord-005646-xhx9pzhj 4014 9 all all DT cord-005646-xhx9pzhj 4014 10 cases case NNS cord-005646-xhx9pzhj 4014 11 ( ( -LRB- cord-005646-xhx9pzhj 4014 12 less less JJR cord-005646-xhx9pzhj 4014 13 than than IN cord-005646-xhx9pzhj 4014 14 8 8 CD cord-005646-xhx9pzhj 4014 15 cells cell NNS cord-005646-xhx9pzhj 4014 16 / / SYM cord-005646-xhx9pzhj 4014 17 ram3 ram3 NN cord-005646-xhx9pzhj 4014 18 ) ) -RRB- cord-005646-xhx9pzhj 4014 19 . . . cord-005646-xhx9pzhj 4015 1 The the DT cord-005646-xhx9pzhj 4015 2 cultives cultive NNS cord-005646-xhx9pzhj 4015 3 were be VBD cord-005646-xhx9pzhj 4015 4 negative negative JJ cord-005646-xhx9pzhj 4015 5 , , , cord-005646-xhx9pzhj 4015 6 and and CC cord-005646-xhx9pzhj 4015 7 the the DT cord-005646-xhx9pzhj 4015 8 final final JJ cord-005646-xhx9pzhj 4015 9 diagnosis diagnosis NN cord-005646-xhx9pzhj 4015 10 was be VBD cord-005646-xhx9pzhj 4015 11 confirmed confirm VBN cord-005646-xhx9pzhj 4015 12 by by IN cord-005646-xhx9pzhj 4015 13 hepatic hepatic JJ cord-005646-xhx9pzhj 4015 14 biopsy biopsy NN cord-005646-xhx9pzhj 4015 15 . . . cord-005646-xhx9pzhj 4016 1 No no DT cord-005646-xhx9pzhj 4016 2 deaths death NNS cord-005646-xhx9pzhj 4016 3 were be VBD cord-005646-xhx9pzhj 4016 4 due due JJ cord-005646-xhx9pzhj 4016 5 to to IN cord-005646-xhx9pzhj 4016 6 Reye Reye NNP cord-005646-xhx9pzhj 4016 7 syndrome syndrome NN cord-005646-xhx9pzhj 4016 8 . . . cord-005646-xhx9pzhj 4017 1 A a DT cord-005646-xhx9pzhj 4017 2 CONTRIBUHON CONTRIBUHON NNP cord-005646-xhx9pzhj 4017 3 TO to IN cord-005646-xhx9pzhj 4017 4 THE the DT cord-005646-xhx9pzhj 4017 5 STUDY study NN cord-005646-xhx9pzhj 4017 6 OF of IN cord-005646-xhx9pzhj 4017 7 REYE REYE NNP cord-005646-xhx9pzhj 4017 8 'S 'S NNP cord-005646-xhx9pzhj 4017 9 SYNDROME syndrome NN cord-005646-xhx9pzhj 4018 1 The the DT cord-005646-xhx9pzhj 4018 2 aulhors aulhor NNS cord-005646-xhx9pzhj 4018 3 analysed analyse VBD cord-005646-xhx9pzhj 4018 4 38 38 CD cord-005646-xhx9pzhj 4018 5 records record NNS cord-005646-xhx9pzhj 4018 6 of of IN cord-005646-xhx9pzhj 4018 7 patients patient NNS cord-005646-xhx9pzhj 4018 8 meeting meet VBG cord-005646-xhx9pzhj 4018 9 all all PDT cord-005646-xhx9pzhj 4018 10 the the DT cord-005646-xhx9pzhj 4018 11 clinical clinical JJ cord-005646-xhx9pzhj 4018 12 , , , cord-005646-xhx9pzhj 4018 13 biochemical biochemical JJ cord-005646-xhx9pzhj 4018 14 and and CC cord-005646-xhx9pzhj 4018 15 anatomic anatomic JJ cord-005646-xhx9pzhj 4018 16 criteria criterion NNS cord-005646-xhx9pzhj 4018 17 put put VBN cord-005646-xhx9pzhj 4018 18 forward forward RB cord-005646-xhx9pzhj 4018 19 by by IN cord-005646-xhx9pzhj 4018 20 Hutrealoch~ Hutrealoch~ NNP cord-005646-xhx9pzhj 4018 21 and and CC cord-005646-xhx9pzhj 4018 22 Samaha Samaha NNP cord-005646-xhx9pzhj 4018 23 ( ( -LRB- cord-005646-xhx9pzhj 4018 24 1975 1975 CD cord-005646-xhx9pzhj 4018 25 ) ) -RRB- cord-005646-xhx9pzhj 4018 26 who who WP cord-005646-xhx9pzhj 4018 27 were be VBD cord-005646-xhx9pzhj 4018 28 Ireated ireate VBN cord-005646-xhx9pzhj 4018 29 at at IN cord-005646-xhx9pzhj 4018 30 the the DT cord-005646-xhx9pzhj 4018 31 emergency emergency NN cord-005646-xhx9pzhj 4018 32 and and CC cord-005646-xhx9pzhj 4018 33 Resusdlation Resusdlation NNP cord-005646-xhx9pzhj 4018 34 Depammlt Depammlt NNP cord-005646-xhx9pzhj 4018 35 tithe tithe VBD cord-005646-xhx9pzhj 4018 36 IPCH IPCH NNP cord-005646-xhx9pzhj 4018 37 in in IN cord-005646-xhx9pzhj 4018 38 10 10 CD cord-005646-xhx9pzhj 4018 39 years year NNS cord-005646-xhx9pzhj 4018 40 . . . cord-005646-xhx9pzhj 4019 1 The the DT cord-005646-xhx9pzhj 4019 2 average average JJ cord-005646-xhx9pzhj 4019 3 age age NN cord-005646-xhx9pzhj 4019 4 of of IN cord-005646-xhx9pzhj 4019 5 the the DT cord-005646-xhx9pzhj 4019 6 children child NNS cord-005646-xhx9pzhj 4019 7 was be VBD cord-005646-xhx9pzhj 4019 8 3 3 CD cord-005646-xhx9pzhj 4019 9 years year NNS cord-005646-xhx9pzhj 4019 10 ( ( -LRB- cord-005646-xhx9pzhj 4019 11 the the DT cord-005646-xhx9pzhj 4019 12 3~umgest 3~umg JJS cord-005646-xhx9pzhj 4019 13 11 11 CD cord-005646-xhx9pzhj 4019 14 monks monk NNS cord-005646-xhx9pzhj 4019 15 and and CC cord-005646-xhx9pzhj 4019 16 the the DT cord-005646-xhx9pzhj 4019 17 driest dry JJS cord-005646-xhx9pzhj 4019 18 7 7 CD cord-005646-xhx9pzhj 4020 1 year~ year~ NNP cord-005646-xhx9pzhj 4020 2 Most Most JJS cord-005646-xhx9pzhj 4020 3 of of IN cord-005646-xhx9pzhj 4020 4 lhon lhon NNP cord-005646-xhx9pzhj 4020 5 ( ( -LRB- cord-005646-xhx9pzhj 4020 6 34/38 34/38 CD cord-005646-xhx9pzhj 4020 7 ) ) -RRB- cord-005646-xhx9pzhj 4020 8 came come VBD cord-005646-xhx9pzhj 4020 9 from from IN cord-005646-xhx9pzhj 4020 10 lhe lhe NNP cord-005646-xhx9pzhj 4020 11 countryside countryside NNP cord-005646-xhx9pzhj 4020 12 to to IN cord-005646-xhx9pzhj 4020 13 lhe lhe NNP cord-005646-xhx9pzhj 4020 14 lmfia~ lmfia~ NNP cord-005646-xhx9pzhj 4020 15 willfin willfin NNP cord-005646-xhx9pzhj 4020 16 24 24 CD cord-005646-xhx9pzhj 4020 17 hours hour NNS cord-005646-xhx9pzhj 4020 18 of of IN cord-005646-xhx9pzhj 4020 19 file file NN cord-005646-xhx9pzhj 4020 20 oulbreak oulbreak NNP cord-005646-xhx9pzhj 4020 21 . . . cord-005646-xhx9pzhj 4021 1 A a DT cord-005646-xhx9pzhj 4021 2 few few JJ cord-005646-xhx9pzhj 4021 3 days day NNS cord-005646-xhx9pzhj 4021 4 previously previously RB cord-005646-xhx9pzhj 4021 5 the the DT cord-005646-xhx9pzhj 4021 6 patients patient NNS cord-005646-xhx9pzhj 4021 7 w¢~ld w¢~ld NN cord-005646-xhx9pzhj 4021 8 have have VBP cord-005646-xhx9pzhj 4021 9 fever fever NN cord-005646-xhx9pzhj 4021 10 ( ( -LRB- cord-005646-xhx9pzhj 4021 11 some some DT cord-005646-xhx9pzhj 4021 12 of of IN cord-005646-xhx9pzhj 4021 13 ahem ahem JJ cord-005646-xhx9pzhj 4021 14 wilh wilh JJ cord-005646-xhx9pzhj 4021 15 diarrhea diarrhea NN cord-005646-xhx9pzhj 4021 16 or or CC cord-005646-xhx9pzhj 4021 17 cough cough NN cord-005646-xhx9pzhj 4021 18 ) ) -RRB- cord-005646-xhx9pzhj 4021 19 , , , cord-005646-xhx9pzhj 4021 20 , , , cord-005646-xhx9pzhj 4021 21 rod rod NN cord-005646-xhx9pzhj 4021 22 vomit vomit NN cord-005646-xhx9pzhj 4021 23 then then RB cord-005646-xhx9pzhj 4021 24 rapidly rapidly RB cord-005646-xhx9pzhj 4021 25 fidl fidl VBN cord-005646-xhx9pzhj 4021 26 into into IN cord-005646-xhx9pzhj 4021 27 coma coma NN cord-005646-xhx9pzhj 4021 28 and and CC cord-005646-xhx9pzhj 4021 29 c c NN cord-005646-xhx9pzhj 4021 30 ~ ~ NFP cord-005646-xhx9pzhj 4021 31 nvuksien nvuksien NNP cord-005646-xhx9pzhj 4021 32 . . . cord-005646-xhx9pzhj 4022 1 They -PRON- PRP cord-005646-xhx9pzhj 4022 2 ~me ~me JJ cord-005646-xhx9pzhj 4022 3 to to IN cord-005646-xhx9pzhj 4022 4 the the DT cord-005646-xhx9pzhj 4022 5 Imtia~ Imtia~ NNP cord-005646-xhx9pzhj 4022 6 with with IN cord-005646-xhx9pzhj 4022 7 the the DT cord-005646-xhx9pzhj 4022 8 signs sign NNS cord-005646-xhx9pzhj 4022 9 of of IN cord-005646-xhx9pzhj 4022 10 typical typical JJ cord-005646-xhx9pzhj 4022 11 increased increase VBN cord-005646-xhx9pzhj 4022 12 inlracranial inlracranial JJ cord-005646-xhx9pzhj 4022 13 pressure pressure NN cord-005646-xhx9pzhj 4022 14 ( ( -LRB- cord-005646-xhx9pzhj 4022 15 stages stage NNS cord-005646-xhx9pzhj 4022 16 2 2 CD cord-005646-xhx9pzhj 4022 17 - - SYM cord-005646-xhx9pzhj 4022 18 4 4 CD cord-005646-xhx9pzhj 4022 19 according accord VBG cord-005646-xhx9pzhj 4022 20 to to IN cord-005646-xhx9pzhj 4022 21 Lovejiy Lovejiy NNP cord-005646-xhx9pzhj 4022 22 for for IN cord-005646-xhx9pzhj 4022 23 most most JJS cord-005646-xhx9pzhj 4022 24 cases case NNS cord-005646-xhx9pzhj 4022 25 ) ) -RRB- cord-005646-xhx9pzhj 4022 26 but but CC cord-005646-xhx9pzhj 4022 27 the the DT cord-005646-xhx9pzhj 4022 28 liver liver NN cord-005646-xhx9pzhj 4022 29 was be VBD cord-005646-xhx9pzhj 4022 30 unllkely unllkely RB cord-005646-xhx9pzhj 4022 31 big big JJ cord-005646-xhx9pzhj 4022 32 . . . cord-005646-xhx9pzhj 4023 1 The the DT cord-005646-xhx9pzhj 4023 2 main main JJ cord-005646-xhx9pzhj 4023 3 biocheafical biocheafical JJ cord-005646-xhx9pzhj 4023 4 dmnge dmnge NN cord-005646-xhx9pzhj 4023 5 of of IN cord-005646-xhx9pzhj 4023 6 the the DT cord-005646-xhx9pzhj 4023 7 blood blood NN cord-005646-xhx9pzhj 4023 8 was be VBD cord-005646-xhx9pzhj 4023 9 acute acute JJ cord-005646-xhx9pzhj 4023 10 hepatic hepatic JJ cord-005646-xhx9pzhj 4023 11 thilure thilure NN cord-005646-xhx9pzhj 4024 1 -The -The . cord-005646-xhx9pzhj 4025 1 bllod bllod NNP cord-005646-xhx9pzhj 4025 2 glucose glucose NN cord-005646-xhx9pzhj 4025 3 decreased decrease VBD cord-005646-xhx9pzhj 4025 4 : : : cord-005646-xhx9pzhj 4025 5 ( ( -LRB- cord-005646-xhx9pzhj 4025 6 ha ha UH cord-005646-xhx9pzhj 4025 7 the the DT cord-005646-xhx9pzhj 4025 8 aver~ aver~ NNP cord-005646-xhx9pzhj 4025 9 23,46n~% 23,46n~% CD cord-005646-xhx9pzhj 4025 10 ( ( -LRB- cord-005646-xhx9pzhj 4025 11 26 26 CD cord-005646-xhx9pzhj 4025 12 ) ) -RRB- cord-005646-xhx9pzhj 4025 13 ~ ~ NFP cord-005646-xhx9pzhj 4025 14 not not RB cord-005646-xhx9pzhj 4025 15 measured measure VBN cord-005646-xhx9pzhj 4025 16 in in IN cord-005646-xhx9pzhj 4025 17 five five CD cord-005646-xhx9pzhj 4025 18 cases case NNS cord-005646-xhx9pzhj 4025 19 ( ( -LRB- cord-005646-xhx9pzhj 4025 20 glucose glucose NN cord-005646-xhx9pzhj 4025 21 a"aces a"ace NNS cord-005646-xhx9pzhj 4025 22 ) ) -RRB- cord-005646-xhx9pzhj 4025 23 . . . cord-005646-xhx9pzhj 4026 1 -The -the WDT cord-005646-xhx9pzhj 4026 2 blood blood NN cord-005646-xhx9pzhj 4026 3 ammonia ammonia NN cord-005646-xhx9pzhj 4026 4 ino ino NNP cord-005646-xhx9pzhj 4027 1 ~ased ~ase VBN cord-005646-xhx9pzhj 4027 2 riven riven NN cord-005646-xhx9pzhj 4027 3 158 158 CD cord-005646-xhx9pzhj 4027 4 to to TO cord-005646-xhx9pzhj 4027 5 275 275 CD cord-005646-xhx9pzhj 4027 6 microg microg NNS cord-005646-xhx9pzhj 4027 7 / / SYM cord-005646-xhx9pzhj 4027 8 dL dl FW cord-005646-xhx9pzhj 4027 9 fin fin FW cord-005646-xhx9pzhj 4027 10 lhe lhe NNP cord-005646-xhx9pzhj 4027 11 average average JJ cord-005646-xhx9pzhj 4027 12 220 220 CD cord-005646-xhx9pzhj 4027 13 , , , cord-005646-xhx9pzhj 4027 14 n n NN cord-005646-xhx9pzhj 4027 15 = = SYM cord-005646-xhx9pzhj 4027 16 3 3 CD cord-005646-xhx9pzhj 4027 17 ) ) -RRB- cord-005646-xhx9pzhj 4028 1 -The -The : cord-005646-xhx9pzhj 4028 2 percentage percentage NN cord-005646-xhx9pzhj 4028 3 of of IN cord-005646-xhx9pzhj 4028 4 p p NN cord-005646-xhx9pzhj 4028 5 ~ ~ CD cord-005646-xhx9pzhj 4028 6 in in IN cord-005646-xhx9pzhj 4028 7 was be VBD cord-005646-xhx9pzhj 4028 8 low low JJ cord-005646-xhx9pzhj 4028 9 , , , cord-005646-xhx9pzhj 4028 10 in in IN cord-005646-xhx9pzhj 4028 11 the the DT cord-005646-xhx9pzhj 4028 12 average average JJ cord-005646-xhx9pzhj 4028 13 44,5 44,5 CD cord-005646-xhx9pzhj 4028 14 % % NN cord-005646-xhx9pzhj 4028 15 ( ( -LRB- cord-005646-xhx9pzhj 4028 16 n--9 n--9 NNP cord-005646-xhx9pzhj 4028 17 ) ) -RRB- cord-005646-xhx9pzhj 4028 18 , , , cord-005646-xhx9pzhj 4028 19 11 11 CD cord-005646-xhx9pzhj 4028 20 % % NN cord-005646-xhx9pzhj 4028 21 at at IN cord-005646-xhx9pzhj 4028 22 the the DT cord-005646-xhx9pzhj 4028 23 lowest low JJS cord-005646-xhx9pzhj 4028 24 ( ( -LRB- cord-005646-xhx9pzhj 4028 25 a a DT cord-005646-xhx9pzhj 4028 26 case case NN cord-005646-xhx9pzhj 4028 27 ofmekaa ofmekaa NN cord-005646-xhx9pzhj 4028 28 lasling lasle VBG cord-005646-xhx9pzhj 4028 29 five five CD cord-005646-xhx9pzhj 4028 30 days day NNS cord-005646-xhx9pzhj 4028 31 was be VBD cord-005646-xhx9pzhj 4028 32 ctwed ctwe VBN cord-005646-xhx9pzhj 4028 33 with with IN cord-005646-xhx9pzhj 4028 34 vitamin vitamin NN cord-005646-xhx9pzhj 4028 35 K K NNP cord-005646-xhx9pzhj 4028 36 ) ) -RRB- cord-005646-xhx9pzhj 4028 37 . . . cord-005646-xhx9pzhj 4029 1 -GOT -GOT -RRB- cord-005646-xhx9pzhj 4030 1 and and CC cord-005646-xhx9pzhj 4030 2 GPT GPT NNP cord-005646-xhx9pzhj 4030 3 enzymes enzyme NNS cord-005646-xhx9pzhj 4030 4 increased increase VBD cord-005646-xhx9pzhj 4030 5 3 3 CD cord-005646-xhx9pzhj 4030 6 -4 -4 CD cord-005646-xhx9pzhj 4030 7 times time NNS cord-005646-xhx9pzhj 4030 8 ( ( -LRB- cord-005646-xhx9pzhj 4030 9 n=14 n=14 NN cord-005646-xhx9pzhj 4030 10 ) ) -RRB- cord-005646-xhx9pzhj 4031 1 Besides besides RB cord-005646-xhx9pzhj 4031 2 , , , cord-005646-xhx9pzhj 4031 3 tht tht NNP cord-005646-xhx9pzhj 4031 4 ~ ~ NFP cord-005646-xhx9pzhj 4031 5 re re IN cord-005646-xhx9pzhj 4031 6 was be VBD cord-005646-xhx9pzhj 4031 7 decompcmated decompcmate VBN cord-005646-xhx9pzhj 4031 8 addt addt NNP cord-005646-xhx9pzhj 4031 9 ~ ~ NFP cord-005646-xhx9pzhj 4031 10 is be VBZ cord-005646-xhx9pzhj 4031 11 with with IN cord-005646-xhx9pzhj 4031 12 lhe lhe NNP cord-005646-xhx9pzhj 4031 13 average average JJ cord-005646-xhx9pzhj 4031 14 valnes valne NNS cord-005646-xhx9pzhj 4031 15 pH pH NNP cord-005646-xhx9pzhj 4031 16 = = NNP cord-005646-xhx9pzhj 4031 17 7.19 7.19 CD cord-005646-xhx9pzhj 4031 18 ; ; : cord-005646-xhx9pzhj 4031 19 pCOz pcoz XX cord-005646-xhx9pzhj 4031 20 = = SYM cord-005646-xhx9pzhj 4031 21 2~6mmHg 2~6mmhg CD cord-005646-xhx9pzhj 4031 22 and and CC cord-005646-xhx9pzhj 4031 23 Eli Eli NNP cord-005646-xhx9pzhj 4032 1 = = SYM cord-005646-xhx9pzhj 4032 2 -1~6 -1~6 NNP cord-005646-xhx9pzhj 4032 3 ~ ~ NFP cord-005646-xhx9pzhj 4032 4 , , , cord-005646-xhx9pzhj 4032 5 ( ( -LRB- cord-005646-xhx9pzhj 4032 6 n~ n~ XX cord-005646-xhx9pzhj 4032 7 ) ) -RRB- cord-005646-xhx9pzhj 4032 8 . . . cord-005646-xhx9pzhj 4033 1 The the DT cord-005646-xhx9pzhj 4033 2 charadaislic charadaislic NN cord-005646-xhx9pzhj 4033 3 dumge dumge NN cord-005646-xhx9pzhj 4033 4 in in IN cord-005646-xhx9pzhj 4033 5 the the DT cord-005646-xhx9pzhj 4033 6 ¢~'ebrospinal ¢~'ebrospinal JJ cord-005646-xhx9pzhj 4033 7 fluid fluid NN cord-005646-xhx9pzhj 4033 8 was be VBD cord-005646-xhx9pzhj 4033 9 a a DT cord-005646-xhx9pzhj 4033 10 low low JJ cord-005646-xhx9pzhj 4033 11 glucose glucose NN cord-005646-xhx9pzhj 4033 12 tx tx NNP cord-005646-xhx9pzhj 4034 1 ~acenWalien ~acenWalien NNP cord-005646-xhx9pzhj 4034 2 h h NNP cord-005646-xhx9pzhj 4035 1 the the DT cord-005646-xhx9pzhj 4035 2 average average NN cord-005646-xhx9pzhj 4035 3 of of IN cord-005646-xhx9pzhj 4035 4 1K65mg 1k65mg CD cord-005646-xhx9pzhj 4035 5 / / SYM cord-005646-xhx9pzhj 4035 6 dL dl NN cord-005646-xhx9pzhj 4035 7 ( ( -LRB- cord-005646-xhx9pzhj 4035 8 3 3 CD cord-005646-xhx9pzhj 4035 9 cases case NNS cord-005646-xhx9pzhj 4035 10 of of IN cord-005646-xhx9pzhj 4035 11 glucose glucose NN cord-005646-xhx9pzhj 4035 12 It'aces It'aces NNPS cord-005646-xhx9pzhj 4035 13 ) ) -RRB- cord-005646-xhx9pzhj 4035 14 ; ; : cord-005646-xhx9pzhj 4035 15 meanwhile meanwhile RB cord-005646-xhx9pzhj 4035 16 protein protein NN cord-005646-xhx9pzhj 4035 17 decreased decrease VBD cord-005646-xhx9pzhj 4035 18 in in IN cord-005646-xhx9pzhj 4035 19 the the DT cord-005646-xhx9pzhj 4035 20 average average NN cord-005646-xhx9pzhj 4035 21 of of IN cord-005646-xhx9pzhj 4035 22 14mg 14mg CD cord-005646-xhx9pzhj 4035 23 / / SYM cord-005646-xhx9pzhj 4035 24 dl dl NN cord-005646-xhx9pzhj 4035 25 ( ( -LRB- cord-005646-xhx9pzhj 4035 26 4 4 CD cord-005646-xhx9pzhj 4035 27 cases case NNS cord-005646-xhx9pzhj 4035 28 below below IN cord-005646-xhx9pzhj 4035 29 10mg 10mg NN cord-005646-xhx9pzhj 4035 30 / / SYM cord-005646-xhx9pzhj 4035 31 dL dl NN cord-005646-xhx9pzhj 4035 32 ) ) -RRB- cord-005646-xhx9pzhj 4035 33 . . . cord-005646-xhx9pzhj 4036 1 Besides besides IN cord-005646-xhx9pzhj 4036 2 ~here ~here DT cord-005646-xhx9pzhj 4036 3 was be VBD cord-005646-xhx9pzhj 4036 4 no no DT cord-005646-xhx9pzhj 4036 5 inflammatory inflammatory JJ cord-005646-xhx9pzhj 4036 6 lesion lesion NN cord-005646-xhx9pzhj 4036 7 ~tion ~tion NN cord-005646-xhx9pzhj 4036 8 ) ) -RRB- cord-005646-xhx9pzhj 4036 9 : : : cord-005646-xhx9pzhj 4036 10 very very RB cord-005646-xhx9pzhj 4036 11 serious serious JJ cord-005646-xhx9pzhj 4036 12 brain brain NN cord-005646-xhx9pzhj 4036 13 oedona oedona NNS cord-005646-xhx9pzhj 4036 14 and and CC cord-005646-xhx9pzhj 4036 15 fatty fatty JJ cord-005646-xhx9pzhj 4036 16 degeneration degeneration NN cord-005646-xhx9pzhj 4036 17 of of IN cord-005646-xhx9pzhj 4036 18 live~ live~ NNP cord-005646-xhx9pzhj 4036 19 scatteredly scatteredly NNP cord-005646-xhx9pzhj 4036 20 or or CC cord-005646-xhx9pzhj 4036 21 parllally parllally NN cord-005646-xhx9pzhj 4036 22 . . . cord-005646-xhx9pzhj 4037 1 Microso Microso NNP cord-005646-xhx9pzhj 4037 2 ~ ~ NFP cord-005646-xhx9pzhj 4037 3 ically ically RB cord-005646-xhx9pzhj 4037 4 ( ( -LRB- cord-005646-xhx9pzhj 4037 5 biopsy biopsy JJ cord-005646-xhx9pzhj 4037 6 and and CC cord-005646-xhx9pzhj 4037 7 necropsy necropsy JJ cord-005646-xhx9pzhj 4037 8 ) ) -RRB- cord-005646-xhx9pzhj 4037 9 in in IN cord-005646-xhx9pzhj 4037 10 file file NN cord-005646-xhx9pzhj 4037 11 brain brain NN cord-005646-xhx9pzhj 4037 12 appeared appear VBD cord-005646-xhx9pzhj 4037 13 bright bright JJ cord-005646-xhx9pzhj 4037 14 space space NN cord-005646-xhx9pzhj 4037 15 around around IN cord-005646-xhx9pzhj 4037 16 blood blood NN cord-005646-xhx9pzhj 4037 17 arteries artery NNS cord-005646-xhx9pzhj 4037 18 and and CC cord-005646-xhx9pzhj 4037 19 glioma glioma NN cord-005646-xhx9pzhj 4037 20 extended extend VBN cord-005646-xhx9pzhj 4037 21 V'lrdmw v'lrdmw NN cord-005646-xhx9pzhj 4037 22 -Robin -Robin NNP cord-005646-xhx9pzhj 4037 23 space space NN cord-005646-xhx9pzhj 4037 24 , , , cord-005646-xhx9pzhj 4037 25 with with IN cord-005646-xhx9pzhj 4037 26 no no DT cord-005646-xhx9pzhj 4037 27 inflammatory inflammatory JJ cord-005646-xhx9pzhj 4037 28 reaction reaction NN cord-005646-xhx9pzhj 4037 29 . . . cord-005646-xhx9pzhj 4038 1 Liver.-the Liver.-the NNP cord-005646-xhx9pzhj 4038 2 sa sa NNP cord-005646-xhx9pzhj 4039 1 ~dure ~dure NNP cord-005646-xhx9pzhj 4039 2 was be VBD cord-005646-xhx9pzhj 4039 3 intact intact JJ cord-005646-xhx9pzhj 4040 1 there there EX cord-005646-xhx9pzhj 4040 2 was be VBD cord-005646-xhx9pzhj 4040 3 no no DT cord-005646-xhx9pzhj 4040 4 " " `` cord-005646-xhx9pzhj 4040 5 " " `` cord-005646-xhx9pzhj 4040 6 mtlammal mtlammal NNP cord-005646-xhx9pzhj 4040 7 ~ ~ NFP cord-005646-xhx9pzhj 4040 8 s3 s3 NNP cord-005646-xhx9pzhj 4040 9 ' ' POS cord-005646-xhx9pzhj 4040 10 cell cell NN cord-005646-xhx9pzhj 4040 11 , , , cord-005646-xhx9pzhj 4040 12 the the DT cord-005646-xhx9pzhj 4040 13 Kupffer Kupffer NNP cord-005646-xhx9pzhj 4040 14 cells cell NNS cord-005646-xhx9pzhj 4040 15 did do VBD cord-005646-xhx9pzhj 4040 16 not not RB cord-005646-xhx9pzhj 4040 17 show show VB cord-005646-xhx9pzhj 4040 18 hyperplasia hyperplasia NN cord-005646-xhx9pzhj 4040 19 but but CC cord-005646-xhx9pzhj 4040 20 show show VBP cord-005646-xhx9pzhj 4040 21 a a DT cord-005646-xhx9pzhj 4040 22 heterogenous heterogenous JJ cord-005646-xhx9pzhj 4040 23 deg deg NN cord-005646-xhx9pzhj 4040 24 ~ ~ NFP cord-005646-xhx9pzhj 4040 25 nerafion nerafion NN cord-005646-xhx9pzhj 4040 26 ~ ~ NFP cord-005646-xhx9pzhj 4040 27 eart eart NNP cord-005646-xhx9pzhj 4040 28 : : : cord-005646-xhx9pzhj 4040 29 also also RB cord-005646-xhx9pzhj 4040 30 showed show VBD cord-005646-xhx9pzhj 4040 31 a a DT cord-005646-xhx9pzhj 4040 32 fatty fatty JJ cord-005646-xhx9pzhj 4040 33 degencralion degencralion NN cord-005646-xhx9pzhj 4040 34 in in IN cord-005646-xhx9pzhj 4040 35 some some DT cord-005646-xhx9pzhj 4040 36 areas area NNS cord-005646-xhx9pzhj 4040 37 of of IN cord-005646-xhx9pzhj 4040 38 the the DT cord-005646-xhx9pzhj 4040 39 myocard myocard NNP cord-005646-xhx9pzhj 4040 40 eelLKidney eelLKidney NNP cord-005646-xhx9pzhj 4040 41 : : : cord-005646-xhx9pzhj 4040 42 the the DT cord-005646-xhx9pzhj 4040 43 ihtty ihtty NNP cord-005646-xhx9pzhj 4040 44 degenerati degenerati NNP cord-005646-xhx9pzhj 4040 45 ~ ~ . cord-005646-xhx9pzhj 4040 46 l l NNP cord-005646-xhx9pzhj 4040 47 scattetedly scattetedly NNP cord-005646-xhx9pzhj 4040 48 in in IN cord-005646-xhx9pzhj 4040 49 the the DT cord-005646-xhx9pzhj 4040 50 tubular tubular JJ cord-005646-xhx9pzhj 4040 51 cell cell NN cord-005646-xhx9pzhj 4040 52 . . . cord-005646-xhx9pzhj 4041 1 Pano Pano NNP cord-005646-xhx9pzhj 4041 2 ~ ~ NFP cord-005646-xhx9pzhj 4041 3 as as IN cord-005646-xhx9pzhj 4041 4 : : : cord-005646-xhx9pzhj 4041 5 fatty fatty JJ cord-005646-xhx9pzhj 4041 6 degeneration degeneration NN cord-005646-xhx9pzhj 4041 7 scattetedly scattetedly RB cord-005646-xhx9pzhj 4041 8 in in IN cord-005646-xhx9pzhj 4041 9 file file NN cord-005646-xhx9pzhj 4041 10 pancreatic pancreatic JJ cord-005646-xhx9pzhj 4041 11 cell cell NN cord-005646-xhx9pzhj 4041 12 . . . cord-005646-xhx9pzhj 4042 1 Two two CD cord-005646-xhx9pzhj 4042 2 cases case NNS cord-005646-xhx9pzhj 4042 3 of of IN cord-005646-xhx9pzhj 4042 4 liver liver NN cord-005646-xhx9pzhj 4042 5 biopsy biopsy NN cord-005646-xhx9pzhj 4042 6 for for IN cord-005646-xhx9pzhj 4042 7 lhe lhe NNP cord-005646-xhx9pzhj 4042 8 2rid 2rid NNP cord-005646-xhx9pzhj 4042 9 lime lime NN cord-005646-xhx9pzhj 4042 10 ( ( -LRB- cord-005646-xhx9pzhj 4042 11 check check VB cord-005646-xhx9pzhj 4042 12 before before IN cord-005646-xhx9pzhj 4042 13 leaving leave VBG cord-005646-xhx9pzhj 4042 14 file file NN cord-005646-xhx9pzhj 4042 15 Inslitute Inslitute NNP cord-005646-xhx9pzhj 4042 16 ) ) -RRB- cord-005646-xhx9pzhj 4042 17 found find VBD cord-005646-xhx9pzhj 4042 18 that that IN cord-005646-xhx9pzhj 4042 19 fatty fatty JJ cord-005646-xhx9pzhj 4042 20 degeneration degeneration NN cord-005646-xhx9pzhj 4042 21 was be VBD cord-005646-xhx9pzhj 4042 22 r r NN cord-005646-xhx9pzhj 4042 23 ~ ~ NFP cord-005646-xhx9pzhj 4042 24 tta~ tta~ CD cord-005646-xhx9pzhj 4042 25 nearty nearty NNP cord-005646-xhx9pzhj 4042 26 ff ff NNP cord-005646-xhx9pzhj 4042 27 ~ ~ NNP cord-005646-xhx9pzhj 4042 28 pletely pletely NNP cord-005646-xhx9pzhj 4042 29 . . . cord-005646-xhx9pzhj 4043 1 The the DT cord-005646-xhx9pzhj 4043 2 exact exact JJ cord-005646-xhx9pzhj 4043 3 muse muse NN cord-005646-xhx9pzhj 4043 4 remained remain VBD cord-005646-xhx9pzhj 4043 5 unknown unknown JJ cord-005646-xhx9pzhj 4043 6 . . . cord-005646-xhx9pzhj 4044 1 Objectives objective NNS cord-005646-xhx9pzhj 4044 2 : : : cord-005646-xhx9pzhj 4045 1 To to TO cord-005646-xhx9pzhj 4045 2 analyse analyse VB cord-005646-xhx9pzhj 4045 3 whether whether IN cord-005646-xhx9pzhj 4045 4 there there EX cord-005646-xhx9pzhj 4045 5 exists exist VBZ cord-005646-xhx9pzhj 4045 6 serum serum NN cord-005646-xhx9pzhj 4045 7 and and CC cord-005646-xhx9pzhj 4045 8 urine urine NN cord-005646-xhx9pzhj 4045 9 electrolyte electrolyte JJ cord-005646-xhx9pzhj 4045 10 disorder disorder NN cord-005646-xhx9pzhj 4045 11 in in IN cord-005646-xhx9pzhj 4045 12 children child NNS cord-005646-xhx9pzhj 4045 13 with with IN cord-005646-xhx9pzhj 4045 14 respiratory respiratory JJ cord-005646-xhx9pzhj 4045 15 failure failure NN cord-005646-xhx9pzhj 4045 16 , , , cord-005646-xhx9pzhj 4045 17 Methods method NNS cord-005646-xhx9pzhj 4045 18 : : : cord-005646-xhx9pzhj 4046 1 We -PRON- PRP cord-005646-xhx9pzhj 4046 2 have have VBP cord-005646-xhx9pzhj 4046 3 made make VBN cord-005646-xhx9pzhj 4046 4 prospective prospective JJ cord-005646-xhx9pzhj 4046 5 study study NN cord-005646-xhx9pzhj 4046 6 of of IN cord-005646-xhx9pzhj 4046 7 48 48 CD cord-005646-xhx9pzhj 4046 8 children child NNS cord-005646-xhx9pzhj 4046 9 in in IN cord-005646-xhx9pzhj 4046 10 our -PRON- PRP$ cord-005646-xhx9pzhj 4046 11 ICU ICU NNP cord-005646-xhx9pzhj 4046 12 during during IN cord-005646-xhx9pzhj 4046 13 a a DT cord-005646-xhx9pzhj 4046 14 12 12 CD cord-005646-xhx9pzhj 4046 15 month month NN cord-005646-xhx9pzhj 4046 16 period period NN cord-005646-xhx9pzhj 4046 17 , , , cord-005646-xhx9pzhj 4046 18 Electrolyte Electrolyte NNP cord-005646-xhx9pzhj 4046 19 concentrations concentration NNS cord-005646-xhx9pzhj 4046 20 were be VBD cord-005646-xhx9pzhj 4046 21 measured measure VBN cord-005646-xhx9pzhj 4046 22 in in IN cord-005646-xhx9pzhj 4046 23 serum serum NN cord-005646-xhx9pzhj 4046 24 and and CC cord-005646-xhx9pzhj 4046 25 urine urine NN cord-005646-xhx9pzhj 4046 26 collected collect VBN cord-005646-xhx9pzhj 4046 27 during during IN cord-005646-xhx9pzhj 4046 28 24 24 CD cord-005646-xhx9pzhj 4046 29 hours hour NNS cord-005646-xhx9pzhj 4047 1 ( ( -LRB- cord-005646-xhx9pzhj 4047 2 sodium sodium NN cord-005646-xhx9pzhj 4047 3 - - HYPH cord-005646-xhx9pzhj 4047 4 Na Na NNP cord-005646-xhx9pzhj 4047 5 , , , cord-005646-xhx9pzhj 4047 6 potassium potassium NN cord-005646-xhx9pzhj 4047 7 K k NN cord-005646-xhx9pzhj 4047 8 , , , cord-005646-xhx9pzhj 4047 9 chloride chloride NN cord-005646-xhx9pzhj 4047 10 - - HYPH cord-005646-xhx9pzhj 4047 11 CI ci NN cord-005646-xhx9pzhj 4047 12 , , , cord-005646-xhx9pzhj 4047 13 calcium calcium NN cord-005646-xhx9pzhj 4047 14 - - : cord-005646-xhx9pzhj 4047 15 Ca ca NN cord-005646-xhx9pzhj 4047 16 , , , cord-005646-xhx9pzhj 4047 17 magnesium magnesium NN cord-005646-xhx9pzhj 4047 18 - - HYPH cord-005646-xhx9pzhj 4047 19 Mg Mg NNP cord-005646-xhx9pzhj 4047 20 and and CC cord-005646-xhx9pzhj 4047 21 phosphorus phosphorus NN cord-005646-xhx9pzhj 4047 22 - - HYPH cord-005646-xhx9pzhj 4047 23 P p NN cord-005646-xhx9pzhj 4047 24 ) ) -RRB- cord-005646-xhx9pzhj 4047 25 . . . cord-005646-xhx9pzhj 4048 1 Results result NNS cord-005646-xhx9pzhj 4048 2 : : : cord-005646-xhx9pzhj 4049 1 Average average JJ cord-005646-xhx9pzhj 4049 2 values value NNS cord-005646-xhx9pzhj 4049 3 in in IN cord-005646-xhx9pzhj 4049 4 serum serum NN cord-005646-xhx9pzhj 4049 5 were be VBD cord-005646-xhx9pzhj 4049 6 : : : cord-005646-xhx9pzhj 4049 7 Na Na NNP cord-005646-xhx9pzhj 4049 8 139.28 139.28 CD cord-005646-xhx9pzhj 4049 9 + + CC cord-005646-xhx9pzhj 4049 10 /-3,20 /-3,20 . cord-005646-xhx9pzhj 4050 1 ( ( -LRB- cord-005646-xhx9pzhj 4050 2 RV:133 RV:133 NNP cord-005646-xhx9pzhj 4050 3 - - HYPH cord-005646-xhx9pzhj 4050 4 146 146 CD cord-005646-xhx9pzhj 4050 5 ) ) -RRB- cord-005646-xhx9pzhj 4050 6 mmol mmol NN cord-005646-xhx9pzhj 4050 7 / / SYM cord-005646-xhx9pzhj 4050 8 I -PRON- PRP cord-005646-xhx9pzhj 4050 9 , , , cord-005646-xhx9pzhj 4050 10 K K NNP cord-005646-xhx9pzhj 4050 11 4.22 4.22 CD cord-005646-xhx9pzhj 4051 1 + + CC cord-005646-xhx9pzhj 4051 2 /-0.55 /-0.55 . cord-005646-xhx9pzhj 4051 3 ( ( -LRB- cord-005646-xhx9pzhj 4051 4 3.3 3.3 CD cord-005646-xhx9pzhj 4051 5 - - SYM cord-005646-xhx9pzhj 4051 6 5.2)mmol 5.2)mmol CD cord-005646-xhx9pzhj 4051 7 / / SYM cord-005646-xhx9pzhj 4051 8 I i NN cord-005646-xhx9pzhj 4051 9 ) ) -RRB- cord-005646-xhx9pzhj 4051 10 , , , cord-005646-xhx9pzhj 4051 11 Cl Cl NNP cord-005646-xhx9pzhj 4051 12 95.20 95.20 CD cord-005646-xhx9pzhj 4051 13 + + CC cord-005646-xhx9pzhj 4052 1 /-3.98 /-3.98 . cord-005646-xhx9pzhj 4053 1 ( ( -LRB- cord-005646-xhx9pzhj 4053 2 93 93 CD cord-005646-xhx9pzhj 4053 3 - - SYM cord-005646-xhx9pzhj 4053 4 106 106 CD cord-005646-xhx9pzhj 4053 5 ) ) -RRB- cord-005646-xhx9pzhj 4053 6 mmol mmol NNP cord-005646-xhx9pzhj 4053 7 / / SYM cord-005646-xhx9pzhj 4053 8 l l NN cord-005646-xhx9pzhj 4053 9 , , , cord-005646-xhx9pzhj 4054 1 Ca ca RB cord-005646-xhx9pzhj 4055 1 2.t2 2.t2 CD cord-005646-xhx9pzhj 4056 1 + + CC cord-005646-xhx9pzhj 4057 1 /-0.12 /-0.12 NNP cord-005646-xhx9pzhj 4057 2 ( ( -LRB- cord-005646-xhx9pzhj 4058 1 2.20 2.20 CD cord-005646-xhx9pzhj 4058 2 2.65)mm01 2.65)mm01 CD cord-005646-xhx9pzhj 4058 3 / / SYM cord-005646-xhx9pzhj 4058 4 I i NN cord-005646-xhx9pzhj 4058 5 ) ) -RRB- cord-005646-xhx9pzhj 4058 6 , , . cord-005646-xhx9pzhj 4059 1 Mg Mg NNP cord-005646-xhx9pzhj 4059 2 0.82 0.82 CD cord-005646-xhx9pzhj 4059 3 + + CC cord-005646-xhx9pzhj 4060 1 /-0.22 /-0.22 . cord-005646-xhx9pzhj 4061 1 ( ( -LRB- cord-005646-xhx9pzhj 4061 2 0.77 0.77 CD cord-005646-xhx9pzhj 4061 3 - - SYM cord-005646-xhx9pzhj 4061 4 1.12)mmol 1.12)mmol CD cord-005646-xhx9pzhj 4061 5 / / SYM cord-005646-xhx9pzhj 4061 6 I. i. NN cord-005646-xhx9pzhj 4061 7 Average average JJ cord-005646-xhx9pzhj 4061 8 electrolyte electrolyte JJ cord-005646-xhx9pzhj 4061 9 levels level NNS cord-005646-xhx9pzhj 4061 10 in in IN cord-005646-xhx9pzhj 4061 11 24 24 CD cord-005646-xhx9pzhj 4061 12 hours hour NNS cord-005646-xhx9pzhj 4061 13 urine urine NN cord-005646-xhx9pzhj 4061 14 were be VBD cord-005646-xhx9pzhj 4061 15 : : : cord-005646-xhx9pzhj 4061 16 Na Na NNP cord-005646-xhx9pzhj 4061 17 64.23 64.23 CD cord-005646-xhx9pzhj 4061 18 ~/~ ~/~ NFP cord-005646-xhx9pzhj 4061 19 44.11 44.11 CD cord-005646-xhx9pzhj 4061 20 ( ( -LRB- cord-005646-xhx9pzhj 4061 21 42 42 CD cord-005646-xhx9pzhj 4061 22 - - SYM cord-005646-xhx9pzhj 4061 23 202)mmol 202)mmol CD cord-005646-xhx9pzhj 4061 24 / / SYM cord-005646-xhx9pzhj 4061 25 day day NN cord-005646-xhx9pzhj 4061 26 . . . cord-005646-xhx9pzhj 4062 1 K K NNP cord-005646-xhx9pzhj 4062 2 22.14 22.14 CD cord-005646-xhx9pzhj 4063 1 + + CC cord-005646-xhx9pzhj 4063 2 /-10.33 /-10.33 . cord-005646-xhx9pzhj 4064 1 ( ( -LRB- cord-005646-xhx9pzhj 4064 2 22 22 CD cord-005646-xhx9pzhj 4064 3 - - SYM cord-005646-xhx9pzhj 4064 4 112)mmol 112)mmol CD cord-005646-xhx9pzhj 4064 5 / / SYM cord-005646-xhx9pzhj 4064 6 day day NN cord-005646-xhx9pzhj 4064 7 , , , cord-005646-xhx9pzhj 4064 8 CI CI NNP cord-005646-xhx9pzhj 4064 9 56.14 56.14 CD cord-005646-xhx9pzhj 4065 1 + + CC cord-005646-xhx9pzhj 4065 2 /-27.22 /-27.22 . cord-005646-xhx9pzhj 4066 1 ( ( -LRB- cord-005646-xhx9pzhj 4066 2 100 100 CD cord-005646-xhx9pzhj 4066 3 - - HYPH cord-005646-xhx9pzhj 4066 4 244)mmol 244)mmol CD cord-005646-xhx9pzhj 4066 5 / / SYM cord-005646-xhx9pzhj 4066 6 day day NN cord-005646-xhx9pzhj 4066 7 , , , cord-005646-xhx9pzhj 4067 1 Ca ca RB cord-005646-xhx9pzhj 4068 1 1.17 1.17 CD cord-005646-xhx9pzhj 4069 1 + + CC cord-005646-xhx9pzhj 4070 1 /-0.13 /-0.13 . cord-005646-xhx9pzhj 4071 1 ( ( -LRB- cord-005646-xhx9pzhj 4071 2 1.68 1.68 CD cord-005646-xhx9pzhj 4071 3 - - SYM cord-005646-xhx9pzhj 4071 4 6.8)mmol 6.8)mmol CD cord-005646-xhx9pzhj 4071 5 / / SYM cord-005646-xhx9pzhj 4071 6 day day NN cord-005646-xhx9pzhj 4071 7 and and CC cord-005646-xhx9pzhj 4071 8 P p NN cord-005646-xhx9pzhj 4071 9 11.89 11.89 CD cord-005646-xhx9pzhj 4072 1 + + CC cord-005646-xhx9pzhj 4073 1 /-7.12 /-7.12 . cord-005646-xhx9pzhj 4074 1 ( ( -LRB- cord-005646-xhx9pzhj 4074 2 11.7 11.7 CD cord-005646-xhx9pzhj 4074 3 - - HYPH cord-005646-xhx9pzhj 4074 4 32)mmol 32)mmol CD cord-005646-xhx9pzhj 4074 5 / / SYM cord-005646-xhx9pzhj 4074 6 day day NN cord-005646-xhx9pzhj 4074 7 . . . cord-005646-xhx9pzhj 4075 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 4075 2 : : : cord-005646-xhx9pzhj 4076 1 Average average JJ cord-005646-xhx9pzhj 4076 2 serum serum NN cord-005646-xhx9pzhj 4076 3 CI ci NN cord-005646-xhx9pzhj 4076 4 and and CC cord-005646-xhx9pzhj 4076 5 Ca Ca NNP cord-005646-xhx9pzhj 4076 6 levels level NNS cord-005646-xhx9pzhj 4076 7 were be VBD cord-005646-xhx9pzhj 4076 8 decreased decrease VBN cord-005646-xhx9pzhj 4076 9 in in IN cord-005646-xhx9pzhj 4076 10 children child NNS cord-005646-xhx9pzhj 4076 11 with with IN cord-005646-xhx9pzhj 4076 12 respiratory respiratory JJ cord-005646-xhx9pzhj 4076 13 failure failure NN cord-005646-xhx9pzhj 4076 14 . . . cord-005646-xhx9pzhj 4077 1 In in IN cord-005646-xhx9pzhj 4077 2 urine urine NN cord-005646-xhx9pzhj 4077 3 , , , cord-005646-xhx9pzhj 4077 4 average average JJ cord-005646-xhx9pzhj 4077 5 K K NNP cord-005646-xhx9pzhj 4077 6 , , , cord-005646-xhx9pzhj 4077 7 CI CI NNP cord-005646-xhx9pzhj 4077 8 , , , cord-005646-xhx9pzhj 4077 9 Ca Ca NNP cord-005646-xhx9pzhj 4077 10 and and CC cord-005646-xhx9pzhj 4077 11 Mg Mg NNP cord-005646-xhx9pzhj 4077 12 levels level NNS cord-005646-xhx9pzhj 4077 13 were be VBD cord-005646-xhx9pzhj 4077 14 decreased decrease VBN cord-005646-xhx9pzhj 4077 15 and and CC cord-005646-xhx9pzhj 4077 16 urine urine NN cord-005646-xhx9pzhj 4077 17 P p NN cord-005646-xhx9pzhj 4077 18 concentration concentration NN cord-005646-xhx9pzhj 4077 19 was be VBD cord-005646-xhx9pzhj 4077 20 increased increase VBN cord-005646-xhx9pzhj 4077 21 . . . cord-005646-xhx9pzhj 4078 1 We -PRON- PRP cord-005646-xhx9pzhj 4078 2 concluded conclude VBD cord-005646-xhx9pzhj 4078 3 that that IN cord-005646-xhx9pzhj 4078 4 serum serum NN cord-005646-xhx9pzhj 4078 5 and and CC cord-005646-xhx9pzhj 4078 6 urine urine NN cord-005646-xhx9pzhj 4078 7 electrolite electrolite JJ cord-005646-xhx9pzhj 4078 8 disbalance disbalance NN cord-005646-xhx9pzhj 4078 9 may may MD cord-005646-xhx9pzhj 4078 10 be be VB cord-005646-xhx9pzhj 4078 11 expected expect VBN cord-005646-xhx9pzhj 4078 12 in in IN cord-005646-xhx9pzhj 4078 13 children child NNS cord-005646-xhx9pzhj 4078 14 with with IN cord-005646-xhx9pzhj 4078 15 respiratory respiratory JJ cord-005646-xhx9pzhj 4078 16 failure failure NN cord-005646-xhx9pzhj 4078 17 . . . cord-005646-xhx9pzhj 4079 1 THE the DT cord-005646-xhx9pzhj 4079 2 NURSE nurse NN cord-005646-xhx9pzhj 4079 3 IS be VBZ cord-005646-xhx9pzhj 4079 4 GOING go VBG cord-005646-xhx9pzhj 4079 5 TO to TO cord-005646-xhx9pzhj 4079 6 KILL kill VB cord-005646-xhx9pzhj 4079 7 ME me PRP cord-005646-xhx9pzhj 4079 8 ! ! . cord-005646-xhx9pzhj 4080 1 ( ( -LRB- cord-005646-xhx9pzhj 4080 2 ICU ICU NNP cord-005646-xhx9pzhj 4080 3 SYNDROME SYNDROME NNP cord-005646-xhx9pzhj 4080 4 ) ) -RRB- cord-005646-xhx9pzhj 4081 1 Anita Anita NNP cord-005646-xhx9pzhj 4081 2 Duvndam Duvndam NNP cord-005646-xhx9pzhj 4081 3 ~ ~ NFP cord-005646-xhx9pzhj 4081 4 , , , cord-005646-xhx9pzhj 4082 1 Sonia Sonia NNP cord-005646-xhx9pzhj 4082 2 v.d v.d NNP cord-005646-xhx9pzhj 4082 3 , , , cord-005646-xhx9pzhj 4082 4 Sluis Sluis NNP cord-005646-xhx9pzhj 4082 5 2 2 CD cord-005646-xhx9pzhj 4082 6 ~Dpt ~Dpt NNS cord-005646-xhx9pzhj 4082 7 . . . cord-005646-xhx9pzhj 4083 1 of of IN cord-005646-xhx9pzhj 4083 2 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 4083 3 , , , cord-005646-xhx9pzhj 4083 4 Div Div NNP cord-005646-xhx9pzhj 4083 5 . . . cord-005646-xhx9pzhj 4084 1 Pediatric Pediatric NNP cord-005646-xhx9pzhj 4084 2 Intensive Intensive NNP cord-005646-xhx9pzhj 4084 3 Care Care NNP cord-005646-xhx9pzhj 4084 4 , , , cord-005646-xhx9pzhj 4084 5 Sophia Sophia NNP cord-005646-xhx9pzhj 4084 6 Children Children NNP cord-005646-xhx9pzhj 4084 7 's 's POS cord-005646-xhx9pzhj 4084 8 Hospital Hospital NNP cord-005646-xhx9pzhj 4084 9 , , , cord-005646-xhx9pzhj 4084 10 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 4084 11 2Dpt 2dpt CD cord-005646-xhx9pzhj 4084 12 . . . cord-005646-xhx9pzhj 4084 13 of of IN cord-005646-xhx9pzhj 4084 14 Pediatrics Pediatrics NNP cord-005646-xhx9pzhj 4084 15 , , , cord-005646-xhx9pzhj 4084 16 Div Div NNP cord-005646-xhx9pzhj 4084 17 . . . cord-005646-xhx9pzhj 4085 1 Pediatric pediatric JJ cord-005646-xhx9pzhj 4085 2 tntensive tntensive NNS cord-005646-xhx9pzhj 4085 3 Care Care NNP cord-005646-xhx9pzhj 4085 4 , , , cord-005646-xhx9pzhj 4085 5 Juliana Juliana NNP cord-005646-xhx9pzhj 4085 6 Children Children NNP cord-005646-xhx9pzhj 4085 7 's 's POS cord-005646-xhx9pzhj 4085 8 Hospital Hospital NNP cord-005646-xhx9pzhj 4085 9 , , , cord-005646-xhx9pzhj 4085 10 The the DT cord-005646-xhx9pzhj 4085 11 Hague Hague NNP cord-005646-xhx9pzhj 4085 12 . . . cord-005646-xhx9pzhj 4086 1 Content content JJ cord-005646-xhx9pzhj 4086 2 description description NN cord-005646-xhx9pzhj 4086 3 : : : cord-005646-xhx9pzhj 4086 4 This this DT cord-005646-xhx9pzhj 4086 5 presentation presentation NN cord-005646-xhx9pzhj 4086 6 will will MD cord-005646-xhx9pzhj 4086 7 provide provide VB cord-005646-xhx9pzhj 4086 8 the the DT cord-005646-xhx9pzhj 4086 9 critical critical JJ cord-005646-xhx9pzhj 4086 10 nurse nurse NN cord-005646-xhx9pzhj 4086 11 with with IN cord-005646-xhx9pzhj 4086 12 background background NN cord-005646-xhx9pzhj 4086 13 information information NN cord-005646-xhx9pzhj 4086 14 concerning concern VBG cord-005646-xhx9pzhj 4086 15 the the DT cord-005646-xhx9pzhj 4086 16 identification identification NN cord-005646-xhx9pzhj 4086 17 , , , cord-005646-xhx9pzhj 4086 18 the the DT cord-005646-xhx9pzhj 4086 19 prevention prevention NN cord-005646-xhx9pzhj 4086 20 and and CC cord-005646-xhx9pzhj 4086 21 management management NN cord-005646-xhx9pzhj 4086 22 of of IN cord-005646-xhx9pzhj 4086 23 the the DT cord-005646-xhx9pzhj 4086 24 critical critical JJ cord-005646-xhx9pzhj 4086 25 ill ill JJ cord-005646-xhx9pzhj 4086 26 child child NN cord-005646-xhx9pzhj 4086 27 who who WP cord-005646-xhx9pzhj 4086 28 has have VBZ cord-005646-xhx9pzhj 4086 29 developed develop VBN cord-005646-xhx9pzhj 4086 30 the the DT cord-005646-xhx9pzhj 4086 31 ICU ICU NNP cord-005646-xhx9pzhj 4086 32 syndrome syndrome NN cord-005646-xhx9pzhj 4086 33 . . . cord-005646-xhx9pzhj 4087 1 The the DT cord-005646-xhx9pzhj 4087 2 results result NNS cord-005646-xhx9pzhj 4087 3 of of IN cord-005646-xhx9pzhj 4087 4 a a DT cord-005646-xhx9pzhj 4087 5 questionnaire questionnaire NN cord-005646-xhx9pzhj 4087 6 concerning concern VBG cord-005646-xhx9pzhj 4087 7 the the DT cord-005646-xhx9pzhj 4087 8 occurrence occurrence NN cord-005646-xhx9pzhj 4087 9 of of IN cord-005646-xhx9pzhj 4087 10 ICU ICU NNP cord-005646-xhx9pzhj 4087 11 syndrome syndrome NN cord-005646-xhx9pzhj 4087 12 on on IN cord-005646-xhx9pzhj 4087 13 a a DT cord-005646-xhx9pzhj 4087 14 PICU PICU NNP cord-005646-xhx9pzhj 4087 15 will will MD cord-005646-xhx9pzhj 4087 16 be be VB cord-005646-xhx9pzhj 4087 17 presented present VBN cord-005646-xhx9pzhj 4087 18 . . . cord-005646-xhx9pzhj 4088 1 Behavioral behavioral JJ cord-005646-xhx9pzhj 4088 2 objectives objective NNS cord-005646-xhx9pzhj 4088 3 : : : cord-005646-xhx9pzhj 4088 4 At at IN cord-005646-xhx9pzhj 4088 5 the the DT cord-005646-xhx9pzhj 4088 6 end end NN cord-005646-xhx9pzhj 4088 7 of of IN cord-005646-xhx9pzhj 4088 8 this this DT cord-005646-xhx9pzhj 4088 9 session session NN cord-005646-xhx9pzhj 4088 10 the the DT cord-005646-xhx9pzhj 4088 11 participant participant NN cord-005646-xhx9pzhj 4088 12 will will MD cord-005646-xhx9pzhj 4088 13 be be VB cord-005646-xhx9pzhj 4088 14 able able JJ cord-005646-xhx9pzhj 4088 15 to to TO cord-005646-xhx9pzhj 4088 16 : : : cord-005646-xhx9pzhj 4088 17 1 1 CD cord-005646-xhx9pzhj 4088 18 . . . cord-005646-xhx9pzhj 4089 1 describe describe VB cord-005646-xhx9pzhj 4089 2 four four CD cord-005646-xhx9pzhj 4089 3 clinical clinical JJ cord-005646-xhx9pzhj 4089 4 symptoms symptom NNS cord-005646-xhx9pzhj 4089 5 of of IN cord-005646-xhx9pzhj 4089 6 the the DT cord-005646-xhx9pzhj 4089 7 tCU tCU NNP cord-005646-xhx9pzhj 4089 8 syndrome syndrome NN cord-005646-xhx9pzhj 4089 9 , , , cord-005646-xhx9pzhj 4089 10 2 2 CD cord-005646-xhx9pzhj 4089 11 . . . cord-005646-xhx9pzhj 4089 12 identify identify VB cord-005646-xhx9pzhj 4089 13 major major JJ cord-005646-xhx9pzhj 4089 14 sources source NNS cord-005646-xhx9pzhj 4089 15 of of IN cord-005646-xhx9pzhj 4089 16 PICU PICU NNP cord-005646-xhx9pzhj 4089 17 environmental environmental JJ cord-005646-xhx9pzhj 4089 18 stress stress NN cord-005646-xhx9pzhj 4089 19 , , , cord-005646-xhx9pzhj 4089 20 3 3 CD cord-005646-xhx9pzhj 4089 21 . . . cord-005646-xhx9pzhj 4090 1 discuss discuss VB cord-005646-xhx9pzhj 4090 2 nursing nursing NN cord-005646-xhx9pzhj 4090 3 's 's POS cord-005646-xhx9pzhj 4090 4 unique unique JJ cord-005646-xhx9pzhj 4090 5 role role NN cord-005646-xhx9pzhj 4090 6 in in IN cord-005646-xhx9pzhj 4090 7 helping help VBG cord-005646-xhx9pzhj 4090 8 the the DT cord-005646-xhx9pzhj 4090 9 child child NN cord-005646-xhx9pzhj 4090 10 to to TO cord-005646-xhx9pzhj 4090 11 cope cope VB cord-005646-xhx9pzhj 4090 12 with with IN cord-005646-xhx9pzhj 4090 13 the the DT cord-005646-xhx9pzhj 4090 14 ICU ICU NNP cord-005646-xhx9pzhj 4090 15 syndrome syndrome NN cord-005646-xhx9pzhj 4090 16 , , , cord-005646-xhx9pzhj 4090 17 4 4 CD cord-005646-xhx9pzhj 4090 18 . . . cord-005646-xhx9pzhj 4091 1 discuss discuss VB cord-005646-xhx9pzhj 4091 2 nursing nursing NN cord-005646-xhx9pzhj 4091 3 's 's POS cord-005646-xhx9pzhj 4091 4 unique unique JJ cord-005646-xhx9pzhj 4091 5 role role NN cord-005646-xhx9pzhj 4091 6 in in IN cord-005646-xhx9pzhj 4091 7 preventing prevent VBG cord-005646-xhx9pzhj 4091 8 ICU ICU NNP cord-005646-xhx9pzhj 4091 9 syndrome syndrome NN cord-005646-xhx9pzhj 4091 10 . . . cord-005646-xhx9pzhj 4092 1 Content content JJ cord-005646-xhx9pzhj 4092 2 outline outline NN cord-005646-xhx9pzhj 4092 3 : : : cord-005646-xhx9pzhj 4092 4 The the DT cord-005646-xhx9pzhj 4092 5 ICU ICU NNP cord-005646-xhx9pzhj 4092 6 syndrome syndrome NN cord-005646-xhx9pzhj 4092 7 is be VBZ cord-005646-xhx9pzhj 4092 8 a a DT cord-005646-xhx9pzhj 4092 9 situation situation NN cord-005646-xhx9pzhj 4092 10 in in IN cord-005646-xhx9pzhj 4092 11 which which WDT cord-005646-xhx9pzhj 4092 12 the the DT cord-005646-xhx9pzhj 4092 13 individual individual NN cord-005646-xhx9pzhj 4092 14 is be VBZ cord-005646-xhx9pzhj 4092 15 not not RB cord-005646-xhx9pzhj 4092 16 able able JJ cord-005646-xhx9pzhj 4092 17 to to TO cord-005646-xhx9pzhj 4092 18 deal deal VB cord-005646-xhx9pzhj 4092 19 with with IN cord-005646-xhx9pzhj 4092 20 changes change NNS cord-005646-xhx9pzhj 4092 21 in in IN cord-005646-xhx9pzhj 4092 22 observation observation NN cord-005646-xhx9pzhj 4092 23 and and CC cord-005646-xhx9pzhj 4092 24 interpretation interpretation NN cord-005646-xhx9pzhj 4092 25 of of IN cord-005646-xhx9pzhj 4092 26 both both CC cord-005646-xhx9pzhj 4092 27 quantity quantity NN cord-005646-xhx9pzhj 4092 28 and and CC cord-005646-xhx9pzhj 4092 29 of of IN cord-005646-xhx9pzhj 4092 30 patterns pattern NNS cord-005646-xhx9pzhj 4092 31 of of IN cord-005646-xhx9pzhj 4092 32 sensory sensory JJ cord-005646-xhx9pzhj 4092 33 perceptions perception NNS cord-005646-xhx9pzhj 4092 34 . . . cord-005646-xhx9pzhj 4093 1 In in IN cord-005646-xhx9pzhj 4093 2 other other JJ cord-005646-xhx9pzhj 4093 3 words word NNS cord-005646-xhx9pzhj 4093 4 the the DT cord-005646-xhx9pzhj 4093 5 borders border NNS cord-005646-xhx9pzhj 4093 6 between between IN cord-005646-xhx9pzhj 4093 7 the the DT cord-005646-xhx9pzhj 4093 8 inner inner JJ cord-005646-xhx9pzhj 4093 9 and and CC cord-005646-xhx9pzhj 4093 10 outer outer JJ cord-005646-xhx9pzhj 4093 11 world world NN cord-005646-xhx9pzhj 4093 12 becomes become VBZ cord-005646-xhx9pzhj 4093 13 unclear unclear JJ cord-005646-xhx9pzhj 4093 14 for for IN cord-005646-xhx9pzhj 4093 15 the the DT cord-005646-xhx9pzhj 4093 16 person person NN cord-005646-xhx9pzhj 4093 17 . . . cord-005646-xhx9pzhj 4094 1 The the DT cord-005646-xhx9pzhj 4094 2 exact exact JJ cord-005646-xhx9pzhj 4094 3 incidence incidence NN cord-005646-xhx9pzhj 4094 4 of of IN cord-005646-xhx9pzhj 4094 5 the the DT cord-005646-xhx9pzhj 4094 6 ICU ICU NNP cord-005646-xhx9pzhj 4094 7 syndrome syndrome NN cord-005646-xhx9pzhj 4094 8 in in IN cord-005646-xhx9pzhj 4094 9 the the DT cord-005646-xhx9pzhj 4094 10 critical critical JJ cord-005646-xhx9pzhj 4094 11 care care NN cord-005646-xhx9pzhj 4094 12 setting setting NN cord-005646-xhx9pzhj 4094 13 is be VBZ cord-005646-xhx9pzhj 4094 14 unknown unknown JJ cord-005646-xhx9pzhj 4094 15 , , , cord-005646-xhx9pzhj 4094 16 We -PRON- PRP cord-005646-xhx9pzhj 4094 17 have have VBP cord-005646-xhx9pzhj 4094 18 limited limit VBN cord-005646-xhx9pzhj 4094 19 knowledge knowledge NN cord-005646-xhx9pzhj 4094 20 of of IN cord-005646-xhx9pzhj 4094 21 the the DT cord-005646-xhx9pzhj 4094 22 occurrence occurrence NN cord-005646-xhx9pzhj 4094 23 of of IN cord-005646-xhx9pzhj 4094 24 the the DT cord-005646-xhx9pzhj 4094 25 ICU ICU NNP cord-005646-xhx9pzhj 4094 26 syndrome syndrome NN cord-005646-xhx9pzhj 4094 27 in in IN cord-005646-xhx9pzhj 4094 28 critical critical JJ cord-005646-xhx9pzhj 4094 29 ill ill JJ cord-005646-xhx9pzhj 4094 30 children child NNS cord-005646-xhx9pzhj 4094 31 . . . cord-005646-xhx9pzhj 4095 1 Yet yet CC cord-005646-xhx9pzhj 4095 2 critical critical JJ cord-005646-xhx9pzhj 4095 3 ill ill JJ cord-005646-xhx9pzhj 4095 4 children child NNS cord-005646-xhx9pzhj 4095 5 in in IN cord-005646-xhx9pzhj 4095 6 our -PRON- PRP$ cord-005646-xhx9pzhj 4095 7 hospitals hospital NNS cord-005646-xhx9pzhj 4095 8 sometimes sometimes RB cord-005646-xhx9pzhj 4095 9 show show VBP cord-005646-xhx9pzhj 4095 10 the the DT cord-005646-xhx9pzhj 4095 11 symptoms symptom NNS cord-005646-xhx9pzhj 4095 12 of of IN cord-005646-xhx9pzhj 4095 13 ICU ICU NNP cord-005646-xhx9pzhj 4095 14 syndromes syndrome NNS cord-005646-xhx9pzhj 4095 15 . . . cord-005646-xhx9pzhj 4096 1 To to TO cord-005646-xhx9pzhj 4096 2 be be VB cord-005646-xhx9pzhj 4096 3 able able JJ cord-005646-xhx9pzhj 4096 4 to to TO cord-005646-xhx9pzhj 4096 5 identify identify VB cord-005646-xhx9pzhj 4096 6 the the DT cord-005646-xhx9pzhj 4096 7 occurrence occurrence NN cord-005646-xhx9pzhj 4096 8 of of IN cord-005646-xhx9pzhj 4096 9 ICU ICU NNP cord-005646-xhx9pzhj 4096 10 syndrome syndrome NN cord-005646-xhx9pzhj 4096 11 we -PRON- PRP cord-005646-xhx9pzhj 4096 12 developed develop VBD cord-005646-xhx9pzhj 4096 13 a a DT cord-005646-xhx9pzhj 4096 14 questionnaire questionnaire NN cord-005646-xhx9pzhj 4096 15 . . . cord-005646-xhx9pzhj 4097 1 The the DT cord-005646-xhx9pzhj 4097 2 thesis thesis NN cord-005646-xhx9pzhj 4097 3 of of IN cord-005646-xhx9pzhj 4097 4 the the DT cord-005646-xhx9pzhj 4097 5 questionnaire questionnaire NN cord-005646-xhx9pzhj 4097 6 was be VBD cord-005646-xhx9pzhj 4097 7 : : : cord-005646-xhx9pzhj 4097 8 Does do VBZ cord-005646-xhx9pzhj 4097 9 the the DT cord-005646-xhx9pzhj 4097 10 ICU ICU NNP cord-005646-xhx9pzhj 4097 11 syndrome syndrome NN cord-005646-xhx9pzhj 4097 12 occur occur VBP cord-005646-xhx9pzhj 4097 13 in in IN cord-005646-xhx9pzhj 4097 14 critical critical JJ cord-005646-xhx9pzhj 4097 15 ill ill JJ cord-005646-xhx9pzhj 4097 16 children child NNS cord-005646-xhx9pzhj 4097 17 in in IN cord-005646-xhx9pzhj 4097 18 the the DT cord-005646-xhx9pzhj 4097 19 age age NN cord-005646-xhx9pzhj 4097 20 between between IN cord-005646-xhx9pzhj 4097 21 three three CD cord-005646-xhx9pzhj 4097 22 and and CC cord-005646-xhx9pzhj 4097 23 ten ten CD cord-005646-xhx9pzhj 4097 24 , , , cord-005646-xhx9pzhj 4097 25 who who WP cord-005646-xhx9pzhj 4097 26 have have VBP cord-005646-xhx9pzhj 4097 27 been be VBN cord-005646-xhx9pzhj 4097 28 intubated intubate VBN cord-005646-xhx9pzhj 4097 29 and/or and/or CC cord-005646-xhx9pzhj 4097 30 ventilated ventilate VBN cord-005646-xhx9pzhj 4097 31 in in IN cord-005646-xhx9pzhj 4097 32 a a DT cord-005646-xhx9pzhj 4097 33 PICU PICU NNP cord-005646-xhx9pzhj 4097 34 ? ? . cord-005646-xhx9pzhj 4098 1 Eighteen eighteen CD cord-005646-xhx9pzhj 4098 2 questionnaires questionnaire NNS cord-005646-xhx9pzhj 4098 3 have have VBP cord-005646-xhx9pzhj 4098 4 been be VBN cord-005646-xhx9pzhj 4098 5 send send VB cord-005646-xhx9pzhj 4098 6 out out RP cord-005646-xhx9pzhj 4098 7 to to IN cord-005646-xhx9pzhj 4098 8 parents parent NNS cord-005646-xhx9pzhj 4098 9 of of IN cord-005646-xhx9pzhj 4098 10 critical critical JJ cord-005646-xhx9pzhj 4098 11 ill ill JJ cord-005646-xhx9pzhj 4098 12 children child NNS cord-005646-xhx9pzhj 4098 13 in in IN cord-005646-xhx9pzhj 4098 14 two two CD cord-005646-xhx9pzhj 4098 15 hospitals hospital NNS cord-005646-xhx9pzhj 4098 16 . . . cord-005646-xhx9pzhj 4099 1 The the DT cord-005646-xhx9pzhj 4099 2 response response NN cord-005646-xhx9pzhj 4099 3 was be VBD cord-005646-xhx9pzhj 4099 4 90 90 CD cord-005646-xhx9pzhj 4099 5 percent percent NN cord-005646-xhx9pzhj 4099 6 . . . cord-005646-xhx9pzhj 4100 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 4100 2 : : : cord-005646-xhx9pzhj 4100 3 1 1 CD cord-005646-xhx9pzhj 4100 4 . . . cord-005646-xhx9pzhj 4101 1 Most Most JJS cord-005646-xhx9pzhj 4101 2 of of IN cord-005646-xhx9pzhj 4101 3 the the DT cord-005646-xhx9pzhj 4101 4 children child NNS cord-005646-xhx9pzhj 4101 5 were be VBD cord-005646-xhx9pzhj 4101 6 anxious anxious JJ cord-005646-xhx9pzhj 4101 7 ( ( -LRB- cord-005646-xhx9pzhj 4101 8 n=11 n=11 NNP cord-005646-xhx9pzhj 4101 9 ) ) -RRB- cord-005646-xhx9pzhj 4101 10 , , , cord-005646-xhx9pzhj 4101 11 showed show VBD cord-005646-xhx9pzhj 4101 12 regression regression NN cord-005646-xhx9pzhj 4101 13 ( ( -LRB- cord-005646-xhx9pzhj 4101 14 n=8 n=8 NN cord-005646-xhx9pzhj 4101 15 ) ) -RRB- cord-005646-xhx9pzhj 4101 16 or or CC cord-005646-xhx9pzhj 4101 17 had have VBD cord-005646-xhx9pzhj 4101 18 sleeping sleep VBG cord-005646-xhx9pzhj 4101 19 problems problem NNS cord-005646-xhx9pzhj 4101 20 ( ( -LRB- cord-005646-xhx9pzhj 4101 21 n n NN cord-005646-xhx9pzhj 4101 22 - - HYPH cord-005646-xhx9pzhj 4101 23 lO lO NNP cord-005646-xhx9pzhj 4101 24 ) ) -RRB- cord-005646-xhx9pzhj 4101 25 during during IN cord-005646-xhx9pzhj 4101 26 the the DT cord-005646-xhx9pzhj 4101 27 stay stay NN cord-005646-xhx9pzhj 4101 28 on on IN cord-005646-xhx9pzhj 4101 29 the the DT cord-005646-xhx9pzhj 4101 30 PICU PICU NNP cord-005646-xhx9pzhj 4101 31 . . . cord-005646-xhx9pzhj 4102 1 2 2 LS cord-005646-xhx9pzhj 4102 2 . . . cord-005646-xhx9pzhj 4103 1 Children child NNS cord-005646-xhx9pzhj 4103 2 showed show VBD cord-005646-xhx9pzhj 4103 3 the the DT cord-005646-xhx9pzhj 4103 4 same same JJ cord-005646-xhx9pzhj 4103 5 problems problem NNS cord-005646-xhx9pzhj 4103 6 after after IN cord-005646-xhx9pzhj 4103 7 discharge discharge NN cord-005646-xhx9pzhj 4103 8 . . . cord-005646-xhx9pzhj 4104 1 3 3 LS cord-005646-xhx9pzhj 4104 2 . . . cord-005646-xhx9pzhj 4105 1 There there EX cord-005646-xhx9pzhj 4105 2 is be VBZ cord-005646-xhx9pzhj 4105 3 no no DT cord-005646-xhx9pzhj 4105 4 relationship relationship NN cord-005646-xhx9pzhj 4105 5 between between IN cord-005646-xhx9pzhj 4105 6 environmental environmental JJ cord-005646-xhx9pzhj 4105 7 factors factor NNS cord-005646-xhx9pzhj 4105 8 and and CC cord-005646-xhx9pzhj 4105 9 symptoms symptom NNS cord-005646-xhx9pzhj 4105 10 of of IN cord-005646-xhx9pzhj 4105 11 the the DT cord-005646-xhx9pzhj 4105 12 tCU tCU NNP cord-005646-xhx9pzhj 4105 13 syndrome syndrome NN cord-005646-xhx9pzhj 4105 14 during during IN cord-005646-xhx9pzhj 4105 15 the the DT cord-005646-xhx9pzhj 4105 16 stay stay NN cord-005646-xhx9pzhj 4105 17 . . . cord-005646-xhx9pzhj 4106 1 4 4 LS cord-005646-xhx9pzhj 4106 2 . . . cord-005646-xhx9pzhj 4107 1 There there EX cord-005646-xhx9pzhj 4107 2 is be VBZ cord-005646-xhx9pzhj 4107 3 no no DT cord-005646-xhx9pzhj 4107 4 relationship relationship NN cord-005646-xhx9pzhj 4107 5 between between IN cord-005646-xhx9pzhj 4107 6 preexistential preexistential JJ cord-005646-xhx9pzhj 4107 7 behavior behavior NN cord-005646-xhx9pzhj 4107 8 and and CC cord-005646-xhx9pzhj 4107 9 symptoms symptom NNS cord-005646-xhx9pzhj 4107 10 of of IN cord-005646-xhx9pzhj 4107 11 the the DT cord-005646-xhx9pzhj 4107 12 ICU ICU NNP cord-005646-xhx9pzhj 4107 13 syndrome syndrome NN cord-005646-xhx9pzhj 4107 14 during during IN cord-005646-xhx9pzhj 4107 15 the the DT cord-005646-xhx9pzhj 4107 16 stay stay NN cord-005646-xhx9pzhj 4107 17 . . . cord-005646-xhx9pzhj 4108 1 Because because IN cord-005646-xhx9pzhj 4108 2 the the DT cord-005646-xhx9pzhj 4108 3 lack lack NN cord-005646-xhx9pzhj 4108 4 of of IN cord-005646-xhx9pzhj 4108 5 a a DT cord-005646-xhx9pzhj 4108 6 scientific scientific JJ cord-005646-xhx9pzhj 4108 7 definition definition NN cord-005646-xhx9pzhj 4108 8 for for IN cord-005646-xhx9pzhj 4108 9 the the DT cord-005646-xhx9pzhj 4108 10 ICU ICU NNP cord-005646-xhx9pzhj 4108 11 syndrome syndrome NN cord-005646-xhx9pzhj 4108 12 in in IN cord-005646-xhx9pzhj 4108 13 children child NNS cord-005646-xhx9pzhj 4108 14 and and CC cord-005646-xhx9pzhj 4108 15 good good JJ cord-005646-xhx9pzhj 4108 16 criteria criterion NNS cord-005646-xhx9pzhj 4108 17 for for IN cord-005646-xhx9pzhj 4108 18 diagnosis diagnosis NN cord-005646-xhx9pzhj 4108 19 , , , cord-005646-xhx9pzhj 4108 20 we -PRON- PRP cord-005646-xhx9pzhj 4108 21 were be VBD cord-005646-xhx9pzhj 4108 22 not not RB cord-005646-xhx9pzhj 4108 23 able able JJ cord-005646-xhx9pzhj 4108 24 to to TO cord-005646-xhx9pzhj 4108 25 get get VB cord-005646-xhx9pzhj 4108 26 an an DT cord-005646-xhx9pzhj 4108 27 answer answer NN cord-005646-xhx9pzhj 4108 28 to to IN cord-005646-xhx9pzhj 4108 29 our -PRON- PRP$ cord-005646-xhx9pzhj 4108 30 thesis thesis NN cord-005646-xhx9pzhj 4108 31 . . . cord-005646-xhx9pzhj 4109 1 More More JJR cord-005646-xhx9pzhj 4109 2 research research NN cord-005646-xhx9pzhj 4109 3 is be VBZ cord-005646-xhx9pzhj 4109 4 needed need VBN cord-005646-xhx9pzhj 4109 5 . . . cord-005646-xhx9pzhj 4110 1 Continuous continuous JJ cord-005646-xhx9pzhj 4110 2 Veno Veno NNP cord-005646-xhx9pzhj 4110 3 Venous Venous NNP cord-005646-xhx9pzhj 4110 4 Haemofiltration Haemofiltration NNP cord-005646-xhx9pzhj 4110 5 ( ( -LRB- cord-005646-xhx9pzhj 4110 6 CVVH CVVH NNP cord-005646-xhx9pzhj 4110 7 ) ) -RRB- cord-005646-xhx9pzhj 4110 8 was be VBD cord-005646-xhx9pzhj 4110 9 adopted adopt VBN cord-005646-xhx9pzhj 4110 10 as as IN cord-005646-xhx9pzhj 4110 11 a a DT cord-005646-xhx9pzhj 4110 12 first first JJ cord-005646-xhx9pzhj 4110 13 line line NN cord-005646-xhx9pzhj 4110 14 renal renal JJ cord-005646-xhx9pzhj 4110 15 replacement replacement NN cord-005646-xhx9pzhj 4110 16 therapy therapy NN cord-005646-xhx9pzhj 4110 17 in in IN cord-005646-xhx9pzhj 4110 18 our -PRON- PRP$ cord-005646-xhx9pzhj 4110 19 Paediatric Paediatric NNP cord-005646-xhx9pzhj 4110 20 Intensive Intensive NNP cord-005646-xhx9pzhj 4110 21 Care Care NNP cord-005646-xhx9pzhj 4110 22 Unit Unit NNP cord-005646-xhx9pzhj 4110 23 ( ( -LRB- cord-005646-xhx9pzhj 4110 24 PICU PICU NNP cord-005646-xhx9pzhj 4110 25 ) ) -RRB- cord-005646-xhx9pzhj 4110 26 some some DT cord-005646-xhx9pzhj 4110 27 three three CD cord-005646-xhx9pzhj 4110 28 years year NNS cord-005646-xhx9pzhj 4110 29 ago ago RB cord-005646-xhx9pzhj 4110 30 . . . cord-005646-xhx9pzhj 4111 1 ~/he ~/he JJ cord-005646-xhx9pzhj 4111 2 process process NN cord-005646-xhx9pzhj 4111 3 of of IN cord-005646-xhx9pzhj 4111 4 introduction introduction NN cord-005646-xhx9pzhj 4111 5 and and CC cord-005646-xhx9pzhj 4111 6 development development NN cord-005646-xhx9pzhj 4111 7 of of IN cord-005646-xhx9pzhj 4111 8 CVVH CVVH NNP cord-005646-xhx9pzhj 4111 9 proved prove VBD cord-005646-xhx9pzhj 4111 10 to to TO cord-005646-xhx9pzhj 4111 11 be be VB cord-005646-xhx9pzhj 4111 12 an an DT cord-005646-xhx9pzhj 4111 13 exciting exciting JJ cord-005646-xhx9pzhj 4111 14 challenge challenge NN cord-005646-xhx9pzhj 4111 15 for for IN cord-005646-xhx9pzhj 4111 16 nurses nurse NNS cord-005646-xhx9pzhj 4112 1 as as IN cord-005646-xhx9pzhj 4112 2 indeed indeed RB cord-005646-xhx9pzhj 4112 3 it -PRON- PRP cord-005646-xhx9pzhj 4112 4 was be VBD cord-005646-xhx9pzhj 4112 5 for for IN cord-005646-xhx9pzhj 4112 6 the the DT cord-005646-xhx9pzhj 4112 7 whole whole JJ cord-005646-xhx9pzhj 4112 8 multidisciplinary multidisciplinary JJ cord-005646-xhx9pzhj 4112 9 team team NN cord-005646-xhx9pzhj 4112 10 involved involve VBN cord-005646-xhx9pzhj 4112 11 . . . cord-005646-xhx9pzhj 4113 1 We -PRON- PRP cord-005646-xhx9pzhj 4113 2 have have VBP cord-005646-xhx9pzhj 4113 3 successfully successfully RB cord-005646-xhx9pzhj 4113 4 used use VBN cord-005646-xhx9pzhj 4113 5 CVVH CVVH NNP cord-005646-xhx9pzhj 4113 6 in in IN cord-005646-xhx9pzhj 4113 7 the the DT cord-005646-xhx9pzhj 4113 8 treatment treatment NN cord-005646-xhx9pzhj 4113 9 of of IN cord-005646-xhx9pzhj 4113 10 over over IN cord-005646-xhx9pzhj 4113 11 20 20 CD cord-005646-xhx9pzhj 4113 12 infants infant NNS cord-005646-xhx9pzhj 4113 13 and and CC cord-005646-xhx9pzhj 4113 14 children child NNS cord-005646-xhx9pzhj 4113 15 , , , cord-005646-xhx9pzhj 4113 16 weighing weigh VBG cord-005646-xhx9pzhj 4113 17 between between IN cord-005646-xhx9pzhj 4113 18 3 3 CD cord-005646-xhx9pzhj 4113 19 - - SYM cord-005646-xhx9pzhj 4113 20 85 85 CD cord-005646-xhx9pzhj 4113 21 kg kg NNS cord-005646-xhx9pzhj 4113 22 . . . cord-005646-xhx9pzhj 4114 1 The the DT cord-005646-xhx9pzhj 4114 2 range range NN cord-005646-xhx9pzhj 4114 3 of of IN cord-005646-xhx9pzhj 4114 4 conditions condition NNS cord-005646-xhx9pzhj 4114 5 treated treat VBN cord-005646-xhx9pzhj 4114 6 is be VBZ cord-005646-xhx9pzhj 4114 7 ever ever RB cord-005646-xhx9pzhj 4114 8 increasing increase VBG cord-005646-xhx9pzhj 4114 9 . . . cord-005646-xhx9pzhj 4115 1 To to IN cord-005646-xhx9pzhj 4115 2 date date NN cord-005646-xhx9pzhj 4115 3 we -PRON- PRP cord-005646-xhx9pzhj 4115 4 have have VBP cord-005646-xhx9pzhj 4115 5 not not RB cord-005646-xhx9pzhj 4115 6 only only RB cord-005646-xhx9pzhj 4115 7 used use VBN cord-005646-xhx9pzhj 4115 8 CVVH CVVH NNP cord-005646-xhx9pzhj 4115 9 for for IN cord-005646-xhx9pzhj 4115 10 patients patient NNS cord-005646-xhx9pzhj 4115 11 in in IN cord-005646-xhx9pzhj 4115 12 renal renal JJ cord-005646-xhx9pzhj 4115 13 failure failure NN cord-005646-xhx9pzhj 4115 14 and and CC cord-005646-xhx9pzhj 4115 15 fluid fluid JJ cord-005646-xhx9pzhj 4115 16 overload overload NN cord-005646-xhx9pzhj 4115 17 , , , cord-005646-xhx9pzhj 4115 18 but but CC cord-005646-xhx9pzhj 4115 19 also also RB cord-005646-xhx9pzhj 4115 20 to to TO cord-005646-xhx9pzhj 4115 21 gain gain VB cord-005646-xhx9pzhj 4115 22 biochemical biochemical JJ cord-005646-xhx9pzhj 4115 23 control control NN cord-005646-xhx9pzhj 4115 24 in in IN cord-005646-xhx9pzhj 4115 25 tumour tumour NN cord-005646-xhx9pzhj 4115 26 lysis lysis NN cord-005646-xhx9pzhj 4115 27 syndrome syndrome NN cord-005646-xhx9pzhj 4115 28 - - HYPH cord-005646-xhx9pzhj 4115 29 and and CC cord-005646-xhx9pzhj 4115 30 metabolic metabolic JJ cord-005646-xhx9pzhj 4115 31 disorders disorder NNS cord-005646-xhx9pzhj 4115 32 . . . cord-005646-xhx9pzhj 4116 1 Other other JJ cord-005646-xhx9pzhj 4116 2 distinct distinct JJ cord-005646-xhx9pzhj 4116 3 patient patient JJ cord-005646-xhx9pzhj 4116 4 benefits benefit NNS cord-005646-xhx9pzhj 4116 5 in in IN cord-005646-xhx9pzhj 4116 6 comparison comparison NN cord-005646-xhx9pzhj 4116 7 with with IN cord-005646-xhx9pzhj 4116 8 more more JJR cord-005646-xhx9pzhj 4116 9 conventional conventional JJ cord-005646-xhx9pzhj 4116 10 means mean NNS cord-005646-xhx9pzhj 4116 11 of of IN cord-005646-xhx9pzhj 4116 12 renal renal JJ cord-005646-xhx9pzhj 4116 13 replacement replacement NN cord-005646-xhx9pzhj 4116 14 therapies therapy NNS cord-005646-xhx9pzhj 4116 15 are be VBP cord-005646-xhx9pzhj 4116 16 that that DT cord-005646-xhx9pzhj 4116 17 , , , cord-005646-xhx9pzhj 4116 18 it -PRON- PRP cord-005646-xhx9pzhj 4116 19 is be VBZ cord-005646-xhx9pzhj 4116 20 a a DT cord-005646-xhx9pzhj 4116 21 continuous continuous JJ cord-005646-xhx9pzhj 4116 22 controlled control VBN cord-005646-xhx9pzhj 4116 23 treatment treatment NN cord-005646-xhx9pzhj 4116 24 being be VBG cord-005646-xhx9pzhj 4116 25 extremely extremely RB cord-005646-xhx9pzhj 4116 26 effective effective JJ cord-005646-xhx9pzhj 4116 27 in in IN cord-005646-xhx9pzhj 4116 28 creating create VBG cord-005646-xhx9pzhj 4116 29 ' ' `` cord-005646-xhx9pzhj 4116 30 space space NN cord-005646-xhx9pzhj 4116 31 ' ' '' cord-005646-xhx9pzhj 4116 32 for for IN cord-005646-xhx9pzhj 4116 33 nutrition nutrition NN cord-005646-xhx9pzhj 4116 34 , , , cord-005646-xhx9pzhj 4116 35 which which WDT cord-005646-xhx9pzhj 4116 36 is be VBZ cord-005646-xhx9pzhj 4116 37 especially especially RB cord-005646-xhx9pzhj 4116 38 important important JJ cord-005646-xhx9pzhj 4116 39 in in IN cord-005646-xhx9pzhj 4116 40 the the DT cord-005646-xhx9pzhj 4116 41 fluid fluid NN cord-005646-xhx9pzhj 4116 42 restricted restrict VBN cord-005646-xhx9pzhj 4116 43 , , , cord-005646-xhx9pzhj 4116 44 catabolic catabolic JJ cord-005646-xhx9pzhj 4116 45 patient patient NN cord-005646-xhx9pzhj 4116 46 . . . cord-005646-xhx9pzhj 4117 1 Of of IN cord-005646-xhx9pzhj 4117 2 paramount paramount JJ cord-005646-xhx9pzhj 4117 3 importance importance NN cord-005646-xhx9pzhj 4117 4 in in IN cord-005646-xhx9pzhj 4117 5 providing provide VBG cord-005646-xhx9pzhj 4117 6 this this DT cord-005646-xhx9pzhj 4117 7 level level NN cord-005646-xhx9pzhj 4117 8 of of IN cord-005646-xhx9pzhj 4117 9 service service NN cord-005646-xhx9pzhj 4117 10 is be VBZ cord-005646-xhx9pzhj 4117 11 the the DT cord-005646-xhx9pzhj 4117 12 education education NN cord-005646-xhx9pzhj 4117 13 and and CC cord-005646-xhx9pzhj 4117 14 training training NN cord-005646-xhx9pzhj 4117 15 necessary necessary JJ cord-005646-xhx9pzhj 4117 16 to to TO cord-005646-xhx9pzhj 4117 17 impart impart VB cord-005646-xhx9pzhj 4117 18 the the DT cord-005646-xhx9pzhj 4117 19 skills skill NNS cord-005646-xhx9pzhj 4117 20 and and CC cord-005646-xhx9pzhj 4117 21 knowledge knowledge NN cord-005646-xhx9pzhj 4117 22 for for IN cord-005646-xhx9pzhj 4117 23 nurses nurse NNS cord-005646-xhx9pzhj 4117 24 to to TO cord-005646-xhx9pzhj 4117 25 become become VB cord-005646-xhx9pzhj 4117 26 expert expert JJ cord-005646-xhx9pzhj 4117 27 practitioners practitioner NNS cord-005646-xhx9pzhj 4117 28 in in IN cord-005646-xhx9pzhj 4117 29 this this DT cord-005646-xhx9pzhj 4117 30 field field NN cord-005646-xhx9pzhj 4117 31 . . . cord-005646-xhx9pzhj 4118 1 We -PRON- PRP cord-005646-xhx9pzhj 4118 2 now now RB cord-005646-xhx9pzhj 4118 3 have have VBP cord-005646-xhx9pzhj 4118 4 a a DT cord-005646-xhx9pzhj 4118 5 teem teem NN cord-005646-xhx9pzhj 4118 6 of of IN cord-005646-xhx9pzhj 4118 7 highly highly RB cord-005646-xhx9pzhj 4118 8 advanced advanced JJ cord-005646-xhx9pzhj 4118 9 practitioners practitioner NNS cord-005646-xhx9pzhj 4118 10 who who WP cord-005646-xhx9pzhj 4118 11 have have VBP cord-005646-xhx9pzhj 4118 12 developed develop VBN cord-005646-xhx9pzhj 4118 13 their -PRON- PRP$ cord-005646-xhx9pzhj 4118 14 nursing nursing NN cord-005646-xhx9pzhj 4118 15 skills skill NNS cord-005646-xhx9pzhj 4118 16 to to TO cord-005646-xhx9pzhj 4118 17 provide provide VB cord-005646-xhx9pzhj 4118 18 even even RB cord-005646-xhx9pzhj 4118 19 more more RBR cord-005646-xhx9pzhj 4118 20 holistic holistic JJ cord-005646-xhx9pzhj 4118 21 care care NN cord-005646-xhx9pzhj 4118 22 for for IN cord-005646-xhx9pzhj 4118 23 their -PRON- PRP$ cord-005646-xhx9pzhj 4118 24 patients patient NNS cord-005646-xhx9pzhj 4118 25 . . . cord-005646-xhx9pzhj 4119 1 This this DT cord-005646-xhx9pzhj 4119 2 group group NN cord-005646-xhx9pzhj 4119 3 are be VBP cord-005646-xhx9pzhj 4119 4 embracing embrace VBG cord-005646-xhx9pzhj 4119 5 new new JJ cord-005646-xhx9pzhj 4119 6 challenges challenge NNS cord-005646-xhx9pzhj 4119 7 and and CC cord-005646-xhx9pzhj 4119 8 responding respond VBG cord-005646-xhx9pzhj 4119 9 positively positively RB cord-005646-xhx9pzhj 4119 10 to to IN cord-005646-xhx9pzhj 4119 11 the the DT cord-005646-xhx9pzhj 4119 12 developing develop VBG cord-005646-xhx9pzhj 4119 13 service service NN cord-005646-xhx9pzhj 4119 14 whilst whilst IN cord-005646-xhx9pzhj 4119 15 expanding expand VBG cord-005646-xhx9pzhj 4119 16 their -PRON- PRP$ cord-005646-xhx9pzhj 4119 17 knowledge knowledge NN cord-005646-xhx9pzhj 4119 18 base base NN cord-005646-xhx9pzhj 4119 19 . . . cord-005646-xhx9pzhj 4120 1 This this DT cord-005646-xhx9pzhj 4120 2 paper paper NN cord-005646-xhx9pzhj 4120 3 will will MD cord-005646-xhx9pzhj 4120 4 discuss discuss VB cord-005646-xhx9pzhj 4120 5 the the DT cord-005646-xhx9pzhj 4120 6 advantages advantage NNS cord-005646-xhx9pzhj 4120 7 and and CC cord-005646-xhx9pzhj 4120 8 disadvantages disadvantage NNS cord-005646-xhx9pzhj 4120 9 of of IN cord-005646-xhx9pzhj 4120 10 CVVH CVVH NNP cord-005646-xhx9pzhj 4120 11 as as IN cord-005646-xhx9pzhj 4120 12 we -PRON- PRP cord-005646-xhx9pzhj 4120 13 have have VBP cord-005646-xhx9pzhj 4120 14 experienced experience VBN cord-005646-xhx9pzhj 4120 15 , , , cord-005646-xhx9pzhj 4120 16 relating relate VBG cord-005646-xhx9pzhj 4120 17 i i PRP cord-005646-xhx9pzhj 4120 18 t t NN cord-005646-xhx9pzhj 4120 19 to to IN cord-005646-xhx9pzhj 4120 20 the the DT cord-005646-xhx9pzhj 4120 21 wide wide JJ cord-005646-xhx9pzhj 4120 22 variety variety NN cord-005646-xhx9pzhj 4120 23 of of IN cord-005646-xhx9pzhj 4120 24 patients patient NNS cord-005646-xhx9pzhj 4120 25 we -PRON- PRP cord-005646-xhx9pzhj 4120 26 have have VBP cord-005646-xhx9pzhj 4120 27 treated treat VBN cord-005646-xhx9pzhj 4120 28 . . . cord-005646-xhx9pzhj 4121 1 We -PRON- PRP cord-005646-xhx9pzhj 4121 2 wish wish VBP cord-005646-xhx9pzhj 4121 3 to to TO cord-005646-xhx9pzhj 4121 4 share share VB cord-005646-xhx9pzhj 4121 5 how how WRB cord-005646-xhx9pzhj 4121 6 CVVH CVVH NNP cord-005646-xhx9pzhj 4121 7 has have VBZ cord-005646-xhx9pzhj 4121 8 become become VBN cord-005646-xhx9pzhj 4121 9 an an DT cord-005646-xhx9pzhj 4121 10 accepted accepted JJ cord-005646-xhx9pzhj 4121 11 role role NN cord-005646-xhx9pzhj 4121 12 of of IN cord-005646-xhx9pzhj 4121 13 the the DT cord-005646-xhx9pzhj 4121 14 PICU PICU NNP cord-005646-xhx9pzhj 4121 15 nurse nurse NN cord-005646-xhx9pzhj 4121 16 and and CC cord-005646-xhx9pzhj 4121 17 how how WRB cord-005646-xhx9pzhj 4121 18 the the DT cord-005646-xhx9pzhj 4121 19 service service NN cord-005646-xhx9pzhj 4121 20 has have VBZ cord-005646-xhx9pzhj 4121 21 been be VBN cord-005646-xhx9pzhj 4121 22 successfully successfully RB cord-005646-xhx9pzhj 4121 23 implemented implement VBN cord-005646-xhx9pzhj 4121 24 . . . cord-005646-xhx9pzhj 4122 1 integrated integrated NNP cord-005646-xhx9pzhj 4122 2 Care Care NNP cord-005646-xhx9pzhj 4122 3 Pathways Pathways NNPS cord-005646-xhx9pzhj 4122 4 ( ( -LRB- cord-005646-xhx9pzhj 4122 5 ICP ICP NNP cord-005646-xhx9pzhj 4122 6 's 's POS cord-005646-xhx9pzhj 4122 7 ) ) -RRB- cord-005646-xhx9pzhj 4122 8 define define VB cord-005646-xhx9pzhj 4122 9 the the DT cord-005646-xhx9pzhj 4122 10 optimum optimum JJ cord-005646-xhx9pzhj 4122 11 course course NN cord-005646-xhx9pzhj 4122 12 of of IN cord-005646-xhx9pzhj 4122 13 events event NNS cord-005646-xhx9pzhj 4122 14 in in IN cord-005646-xhx9pzhj 4122 15 the the DT cord-005646-xhx9pzhj 4122 16 care care NN cord-005646-xhx9pzhj 4122 17 of of IN cord-005646-xhx9pzhj 4122 18 a a DT cord-005646-xhx9pzhj 4122 19 patient patient NN cord-005646-xhx9pzhj 4122 20 with with IN cord-005646-xhx9pzhj 4122 21 a a DT cord-005646-xhx9pzhj 4122 22 specific specific JJ cord-005646-xhx9pzhj 4122 23 condition condition NN cord-005646-xhx9pzhj 4122 24 , , , cord-005646-xhx9pzhj 4122 25 within within IN cord-005646-xhx9pzhj 4122 26 a a DT cord-005646-xhx9pzhj 4122 27 set set VBN cord-005646-xhx9pzhj 4122 28 timescale timescale NN cord-005646-xhx9pzhj 4122 29 . . . cord-005646-xhx9pzhj 4123 1 Aims aim NNS cord-005646-xhx9pzhj 4123 2 and and CC cord-005646-xhx9pzhj 4123 3 methods method NNS cord-005646-xhx9pzhj 4123 4 : : : cord-005646-xhx9pzhj 4124 1 ICP ICP NNP cord-005646-xhx9pzhj 4124 2 's 's POS cord-005646-xhx9pzhj 4124 3 and and CC cord-005646-xhx9pzhj 4124 4 Case Case NNP cord-005646-xhx9pzhj 4124 5 Management Management NNP cord-005646-xhx9pzhj 4124 6 ( ( -LRB- cord-005646-xhx9pzhj 4124 7 CM CM NNP cord-005646-xhx9pzhj 4124 8 ) ) -RRB- cord-005646-xhx9pzhj 4124 9 were be VBD cord-005646-xhx9pzhj 4124 10 introduced introduce VBN cord-005646-xhx9pzhj 4124 11 to to TO cord-005646-xhx9pzhj 4124 12 evaluate evaluate VB cord-005646-xhx9pzhj 4124 13 and and CC cord-005646-xhx9pzhj 4124 14 improve improve VB cord-005646-xhx9pzhj 4124 15 clinical clinical JJ cord-005646-xhx9pzhj 4124 16 practice practice NN cord-005646-xhx9pzhj 4124 17 . . . cord-005646-xhx9pzhj 4125 1 ICP ICP NNP cord-005646-xhx9pzhj 4125 2 's 's POS cord-005646-xhx9pzhj 4125 3 were be VBD cord-005646-xhx9pzhj 4125 4 developed develop VBN cord-005646-xhx9pzhj 4125 5 for for IN cord-005646-xhx9pzhj 4125 6 patients patient NNS cord-005646-xhx9pzhj 4125 7 undergoing undergo VBG cord-005646-xhx9pzhj 4125 8 surgery surgery NN cord-005646-xhx9pzhj 4125 9 for for IN cord-005646-xhx9pzhj 4125 10 atrial atrial JJ cord-005646-xhx9pzhj 4125 11 septal septal JJ cord-005646-xhx9pzhj 4125 12 defect defect NN cord-005646-xhx9pzhj 4125 13 ( ( -LRB- cord-005646-xhx9pzhj 4125 14 ASD ASD NNP cord-005646-xhx9pzhj 4125 15 ) ) -RRB- cord-005646-xhx9pzhj 4125 16 ventricular ventricular JJ cord-005646-xhx9pzhj 4125 17 septal septal JJ cord-005646-xhx9pzhj 4125 18 defect defect NN cord-005646-xhx9pzhj 4125 19 ( ( -LRB- cord-005646-xhx9pzhj 4125 20 VSD VSD NNP cord-005646-xhx9pzhj 4125 21 ) ) -RRB- cord-005646-xhx9pzhj 4125 22 and and CC cord-005646-xhx9pzhj 4125 23 Fallots Fallots NNP cord-005646-xhx9pzhj 4125 24 tetralogy tetralogy NN cord-005646-xhx9pzhj 4125 25 . . . cord-005646-xhx9pzhj 4126 1 They -PRON- PRP cord-005646-xhx9pzhj 4126 2 were be VBD cord-005646-xhx9pzhj 4126 3 based base VBN cord-005646-xhx9pzhj 4126 4 on on IN cord-005646-xhx9pzhj 4126 5 the the DT cord-005646-xhx9pzhj 4126 6 median median JJ cord-005646-xhx9pzhj 4126 7 experiences experience NNS cord-005646-xhx9pzhj 4126 8 of of IN cord-005646-xhx9pzhj 4126 9 the the DT cord-005646-xhx9pzhj 4126 10 last last JJ cord-005646-xhx9pzhj 4126 11 31 31 CD cord-005646-xhx9pzhj 4126 12 patients patient NNS cord-005646-xhx9pzhj 4126 13 . . . cord-005646-xhx9pzhj 4127 1 108 108 CD cord-005646-xhx9pzhj 4127 2 patients patient NNS cord-005646-xhx9pzhj 4127 3 have have VBP cord-005646-xhx9pzhj 4127 4 been be VBN cord-005646-xhx9pzhj 4127 5 managed manage VBN cord-005646-xhx9pzhj 4127 6 using use VBG cord-005646-xhx9pzhj 4127 7 ICP ICP NNP cord-005646-xhx9pzhj 4127 8 's 's POS cord-005646-xhx9pzhj 4127 9 . . . cord-005646-xhx9pzhj 4128 1 Results result NNS cord-005646-xhx9pzhj 4128 2 : : : cord-005646-xhx9pzhj 4129 1 Analysis analysis NN cord-005646-xhx9pzhj 4129 2 of of IN cord-005646-xhx9pzhj 4129 3 variation variation NN cord-005646-xhx9pzhj 4129 4 from from IN cord-005646-xhx9pzhj 4129 5 the the DT cord-005646-xhx9pzhj 4129 6 ICP ICP NNP cord-005646-xhx9pzhj 4129 7 's 's POS cord-005646-xhx9pzhj 4129 8 shows show VBZ cord-005646-xhx9pzhj 4129 9 a a DT cord-005646-xhx9pzhj 4129 10 reduction reduction NN cord-005646-xhx9pzhj 4129 11 in in IN cord-005646-xhx9pzhj 4129 12 the the DT cord-005646-xhx9pzhj 4129 13 following follow VBG cord-005646-xhx9pzhj 4129 14 potentially potentially RB cord-005646-xhx9pzhj 4129 15 avoidable avoidable JJ cord-005646-xhx9pzhj 4129 16 causes cause NNS cord-005646-xhx9pzhj 4129 17 of of IN cord-005646-xhx9pzhj 4129 18 variation variation NN cord-005646-xhx9pzhj 4129 19 : : : cord-005646-xhx9pzhj 4129 20 Delay delay VB cord-005646-xhx9pzhj 4129 21 in in IN cord-005646-xhx9pzhj 4129 22 extubation extubation NN cord-005646-xhx9pzhj 4129 23 has have VBZ cord-005646-xhx9pzhj 4129 24 been be VBN cord-005646-xhx9pzhj 4129 25 reduced reduce VBN cord-005646-xhx9pzhj 4129 26 from from IN cord-005646-xhx9pzhj 4129 27 29 29 CD cord-005646-xhx9pzhj 4129 28 % % NN cord-005646-xhx9pzhj 4129 29 to to TO cord-005646-xhx9pzhj 4129 30 10 10 CD cord-005646-xhx9pzhj 4129 31 % % NN cord-005646-xhx9pzhj 4129 32 , , , cord-005646-xhx9pzhj 4129 33 and and CC cord-005646-xhx9pzhj 4129 34 31 31 CD cord-005646-xhx9pzhj 4129 35 patients patient NNS cord-005646-xhx9pzhj 4129 36 ( ( -LRB- cord-005646-xhx9pzhj 4129 37 29 29 CD cord-005646-xhx9pzhj 4129 38 % % NN cord-005646-xhx9pzhj 4129 39 ) ) -RRB- cord-005646-xhx9pzhj 4129 40 were be VBD cord-005646-xhx9pzhj 4129 41 extubated extubate VBN cord-005646-xhx9pzhj 4129 42 earlier early RBR cord-005646-xhx9pzhj 4129 43 than than IN cord-005646-xhx9pzhj 4129 44 the the DT cord-005646-xhx9pzhj 4129 45 median median NN cord-005646-xhx9pzhj 4129 46 . . . cord-005646-xhx9pzhj 4130 1 Prolonged prolong VBN cord-005646-xhx9pzhj 4130 2 stay stay VBP cord-005646-xhx9pzhj 4130 3 on on IN cord-005646-xhx9pzhj 4130 4 the the DT cord-005646-xhx9pzhj 4130 5 intensive intensive JJ cord-005646-xhx9pzhj 4130 6 care care NN cord-005646-xhx9pzhj 4130 7 unit unit NN cord-005646-xhx9pzhj 4130 8 ( ( -LRB- cord-005646-xhx9pzhj 4130 9 ICU ICU NNP cord-005646-xhx9pzhj 4130 10 ) ) -RRB- cord-005646-xhx9pzhj 4130 11 has have VBZ cord-005646-xhx9pzhj 4130 12 decreased decrease VBN cord-005646-xhx9pzhj 4130 13 from from IN cord-005646-xhx9pzhj 4130 14 13 13 CD cord-005646-xhx9pzhj 4130 15 % % NN cord-005646-xhx9pzhj 4130 16 to to IN cord-005646-xhx9pzhj 4130 17 0 0 CD cord-005646-xhx9pzhj 4130 18 % % NN cord-005646-xhx9pzhj 4130 19 , , , cord-005646-xhx9pzhj 4130 20 and and CC cord-005646-xhx9pzhj 4130 21 24 24 CD cord-005646-xhx9pzhj 4130 22 patients patient NNS cord-005646-xhx9pzhj 4130 23 ( ( -LRB- cord-005646-xhx9pzhj 4130 24 22 22 CD cord-005646-xhx9pzhj 4130 25 % % NN cord-005646-xhx9pzhj 4130 26 ) ) -RRB- cord-005646-xhx9pzhj 4130 27 were be VBD cord-005646-xhx9pzhj 4130 28 discharged discharge VBN cord-005646-xhx9pzhj 4130 29 to to IN cord-005646-xhx9pzhj 4130 30 the the DT cord-005646-xhx9pzhj 4130 31 ward ward NN cord-005646-xhx9pzhj 4130 32 a a DT cord-005646-xhx9pzhj 4130 33 day day NN cord-005646-xhx9pzhj 4130 34 earlier early RBR cord-005646-xhx9pzhj 4130 35 than than IN cord-005646-xhx9pzhj 4130 36 the the DT cord-005646-xhx9pzhj 4130 37 median median NN cord-005646-xhx9pzhj 4130 38 . . . cord-005646-xhx9pzhj 4131 1 The the DT cord-005646-xhx9pzhj 4131 2 number number NN cord-005646-xhx9pzhj 4131 3 of of IN cord-005646-xhx9pzhj 4131 4 patients patient NNS cord-005646-xhx9pzhj 4131 5 receiving receive VBG cord-005646-xhx9pzhj 4131 6 inadequate inadequate JJ cord-005646-xhx9pzhj 4131 7 post post NN cord-005646-xhx9pzhj 4131 8 operative operative JJ cord-005646-xhx9pzhj 4131 9 analgesia analgesia NN cord-005646-xhx9pzhj 4131 10 has have VBZ cord-005646-xhx9pzhj 4131 11 decreased decrease VBN cord-005646-xhx9pzhj 4131 12 from from IN cord-005646-xhx9pzhj 4131 13 35 35 CD cord-005646-xhx9pzhj 4131 14 % % NN cord-005646-xhx9pzhj 4131 15 to to TO cord-005646-xhx9pzhj 4131 16 15 15 CD cord-005646-xhx9pzhj 4131 17 % % NN cord-005646-xhx9pzhj 4131 18 . . . cord-005646-xhx9pzhj 4132 1 Delayed delay VBN cord-005646-xhx9pzhj 4132 2 feeding feeding NN cord-005646-xhx9pzhj 4132 3 after after IN cord-005646-xhx9pzhj 4132 4 operation operation NN cord-005646-xhx9pzhj 4132 5 has have VBZ cord-005646-xhx9pzhj 4132 6 been be VBN cord-005646-xhx9pzhj 4132 7 reduced reduce VBN cord-005646-xhx9pzhj 4132 8 from from IN cord-005646-xhx9pzhj 4132 9 52 52 CD cord-005646-xhx9pzhj 4132 10 % % NN cord-005646-xhx9pzhj 4132 11 to to IN cord-005646-xhx9pzhj 4132 12 28 28 CD cord-005646-xhx9pzhj 4132 13 % % NN cord-005646-xhx9pzhj 4132 14 . . . cord-005646-xhx9pzhj 4133 1 Unavoidable unavoidable JJ cord-005646-xhx9pzhj 4133 2 delays delay NNS cord-005646-xhx9pzhj 4133 3 in in IN cord-005646-xhx9pzhj 4133 4 extubation extubation NN cord-005646-xhx9pzhj 4133 5 and and CC cord-005646-xhx9pzhj 4133 6 discharge discharge NN cord-005646-xhx9pzhj 4133 7 from from IN cord-005646-xhx9pzhj 4133 8 ICU ICU NNP cord-005646-xhx9pzhj 4133 9 occurred occur VBD cord-005646-xhx9pzhj 4133 10 in in IN cord-005646-xhx9pzhj 4133 11 22 22 CD cord-005646-xhx9pzhj 4133 12 patients patient NNS cord-005646-xhx9pzhj 4133 13 ( ( -LRB- cord-005646-xhx9pzhj 4133 14 20 20 CD cord-005646-xhx9pzhj 4133 15 % % NN cord-005646-xhx9pzhj 4133 16 ) ) -RRB- cord-005646-xhx9pzhj 4133 17 because because IN cord-005646-xhx9pzhj 4133 18 of of IN cord-005646-xhx9pzhj 4133 19 haemodynamic haemodynamic JJ cord-005646-xhx9pzhj 4133 20 instability instability NN cord-005646-xhx9pzhj 4133 21 " " '' cord-005646-xhx9pzhj 4133 22 or or CC cord-005646-xhx9pzhj 4133 23 lung lung NN cord-005646-xhx9pzhj 4133 24 problems problem NNS cord-005646-xhx9pzhj 4133 25 . . . cord-005646-xhx9pzhj 4134 1 CM CM NNP cord-005646-xhx9pzhj 4134 2 utilising utilise VBG cord-005646-xhx9pzhj 4134 3 individualised individualised JJ cord-005646-xhx9pzhj 4134 4 pathways pathway NNS cord-005646-xhx9pzhj 4134 5 for for IN cord-005646-xhx9pzhj 4134 6 these these DT cord-005646-xhx9pzhj 4134 7 patients patient NNS cord-005646-xhx9pzhj 4134 8 has have VBZ cord-005646-xhx9pzhj 4134 9 reduced reduce VBN cord-005646-xhx9pzhj 4134 10 variation variation NN cord-005646-xhx9pzhj 4134 11 in in IN cord-005646-xhx9pzhj 4134 12 care care NN cord-005646-xhx9pzhj 4134 13 which which WDT cord-005646-xhx9pzhj 4134 14 can can MD cord-005646-xhx9pzhj 4134 15 improve improve VB cord-005646-xhx9pzhj 4134 16 patient patient JJ cord-005646-xhx9pzhj 4134 17 outcomes outcome NNS cord-005646-xhx9pzhj 4134 18 . . . cord-005646-xhx9pzhj 4135 1 Pathways pathway NNS cord-005646-xhx9pzhj 4135 2 have have VBP cord-005646-xhx9pzhj 4135 3 been be VBN cord-005646-xhx9pzhj 4135 4 developed develop VBN cord-005646-xhx9pzhj 4135 5 for for IN cord-005646-xhx9pzhj 4135 6 other other JJ cord-005646-xhx9pzhj 4135 7 conditions condition NNS cord-005646-xhx9pzhj 4135 8 and and CC cord-005646-xhx9pzhj 4135 9 it -PRON- PRP cord-005646-xhx9pzhj 4135 10 is be VBZ cord-005646-xhx9pzhj 4135 11 anticipated anticipate VBN cord-005646-xhx9pzhj 4135 12 that that IN cord-005646-xhx9pzhj 4135 13 approximately approximately RB cord-005646-xhx9pzhj 4135 14 , , , cord-005646-xhx9pzhj 4135 15 80 80 CD cord-005646-xhx9pzhj 4135 16 % % NN cord-005646-xhx9pzhj 4135 17 of of IN cord-005646-xhx9pzhj 4135 18 patients patient NNS cord-005646-xhx9pzhj 4135 19 will will MD cord-005646-xhx9pzhj 4135 20 be be VB cord-005646-xhx9pzhj 4135 21 treated treat VBN cord-005646-xhx9pzhj 4135 22 using use VBG cord-005646-xhx9pzhj 4135 23 an an DT cord-005646-xhx9pzhj 4135 24 ICP ICP NNP cord-005646-xhx9pzhj 4135 25 Revision Revision NNP cord-005646-xhx9pzhj 4135 26 of of IN cord-005646-xhx9pzhj 4135 27 ICP ICP NNP cord-005646-xhx9pzhj 4135 28 's 's POS cord-005646-xhx9pzhj 4135 29 results result NNS cord-005646-xhx9pzhj 4135 30 in in IN cord-005646-xhx9pzhj 4135 31 continuous continuous JJ cord-005646-xhx9pzhj 4135 32 evaluation evaluation NN cord-005646-xhx9pzhj 4135 33 and and CC cord-005646-xhx9pzhj 4135 34 improvement improvement NN cord-005646-xhx9pzhj 4135 35 of of IN cord-005646-xhx9pzhj 4135 36 the the DT cord-005646-xhx9pzhj 4135 37 care care NN cord-005646-xhx9pzhj 4135 38 provided provide VBN cord-005646-xhx9pzhj 4135 39 , , , cord-005646-xhx9pzhj 4135 40 Conclusions conclusion NNS cord-005646-xhx9pzhj 4135 41 : : : cord-005646-xhx9pzhj 4136 1 The the DT cord-005646-xhx9pzhj 4136 2 use use NN cord-005646-xhx9pzhj 4136 3 of of IN cord-005646-xhx9pzhj 4136 4 ICP ICP NNP cord-005646-xhx9pzhj 4136 5 's 's POS cord-005646-xhx9pzhj 4136 6 and and CC cord-005646-xhx9pzhj 4136 7 CM CM NNP cord-005646-xhx9pzhj 4136 8 has have VBZ cord-005646-xhx9pzhj 4136 9 improved improve VBN cord-005646-xhx9pzhj 4136 10 patient patient JJ cord-005646-xhx9pzhj 4136 11 care care NN cord-005646-xhx9pzhj 4136 12 and and CC cord-005646-xhx9pzhj 4136 13 decreased decrease VBD cord-005646-xhx9pzhj 4136 14 avoidable avoidable JJ cord-005646-xhx9pzhj 4136 15 delays delay NNS cord-005646-xhx9pzhj 4136 16 and and CC cord-005646-xhx9pzhj 4136 17 variations variation NNS cord-005646-xhx9pzhj 4136 18 . . . cord-005646-xhx9pzhj 4137 1 The the DT cord-005646-xhx9pzhj 4137 2 future future JJ cord-005646-xhx9pzhj 4137 3 development development NN cord-005646-xhx9pzhj 4137 4 of of IN cord-005646-xhx9pzhj 4137 5 other other JJ cord-005646-xhx9pzhj 4137 6 ICP ICP NNP cord-005646-xhx9pzhj 4137 7 's 's POS cord-005646-xhx9pzhj 4137 8 , , , cord-005646-xhx9pzhj 4137 9 combined combine VBN cord-005646-xhx9pzhj 4137 10 with with IN cord-005646-xhx9pzhj 4137 11 a a DT cord-005646-xhx9pzhj 4137 12 case case NN cord-005646-xhx9pzhj 4137 13 managed manage VBN cord-005646-xhx9pzhj 4137 14 model model NN cord-005646-xhx9pzhj 4137 15 for for IN cord-005646-xhx9pzhj 4137 16 selected select VBN cord-005646-xhx9pzhj 4137 17 patients patient NNS cord-005646-xhx9pzhj 4137 18 , , , cord-005646-xhx9pzhj 4137 19 is be VBZ cord-005646-xhx9pzhj 4137 20 seen see VBN cord-005646-xhx9pzhj 4137 21 as as IN cord-005646-xhx9pzhj 4137 22 a a DT cord-005646-xhx9pzhj 4137 23 viable viable JJ cord-005646-xhx9pzhj 4137 24 method method NN cord-005646-xhx9pzhj 4137 25 of of IN cord-005646-xhx9pzhj 4137 26 continuously continuously RB cord-005646-xhx9pzhj 4137 27 improving improve VBG cord-005646-xhx9pzhj 4137 28 patient patient JJ cord-005646-xhx9pzhj 4137 29 care care NN cord-005646-xhx9pzhj 4137 30 . . . cord-005646-xhx9pzhj 4138 1 This this DT cord-005646-xhx9pzhj 4138 2 paper paper NN cord-005646-xhx9pzhj 4138 3 is be VBZ cord-005646-xhx9pzhj 4138 4 a a DT cord-005646-xhx9pzhj 4138 5 retrospective retrospective JJ cord-005646-xhx9pzhj 4138 6 audit audit NN cord-005646-xhx9pzhj 4138 7 of of IN cord-005646-xhx9pzhj 4138 8 24 24 CD cord-005646-xhx9pzhj 4138 9 children child NNS cord-005646-xhx9pzhj 4138 10 who who WP cord-005646-xhx9pzhj 4138 11 received receive VBD cord-005646-xhx9pzhj 4138 12 Continuous Continuous NNP cord-005646-xhx9pzhj 4138 13 Veno Veno NNP cord-005646-xhx9pzhj 4138 14 Venous Venous NNP cord-005646-xhx9pzhj 4138 15 Haemofiltration Haemofiltration NNP cord-005646-xhx9pzhj 4138 16 ( ( -LRB- cord-005646-xhx9pzhj 4138 17 CWH CWH NNP cord-005646-xhx9pzhj 4138 18 ) ) -RRB- cord-005646-xhx9pzhj 4138 19 whilst whilst IN cord-005646-xhx9pzhj 4138 20 on on IN cord-005646-xhx9pzhj 4138 21 the the DT cord-005646-xhx9pzhj 4138 22 Paediatrie Paediatrie NNP cord-005646-xhx9pzhj 4138 23 Intensive Intensive NNP cord-005646-xhx9pzhj 4138 24 Care Care NNP cord-005646-xhx9pzhj 4138 25 Unit Unit NNP cord-005646-xhx9pzhj 4138 26 ( ( -LRB- cord-005646-xhx9pzhj 4138 27 PICU PICU NNP cord-005646-xhx9pzhj 4138 28 ) ) -RRB- cord-005646-xhx9pzhj 4138 29 , , , cord-005646-xhx9pzhj 4138 30 Data Data NNP cord-005646-xhx9pzhj 4138 31 was be VBD cord-005646-xhx9pzhj 4138 32 collected collect VBN cord-005646-xhx9pzhj 4138 33 over over IN cord-005646-xhx9pzhj 4138 34 a a DT cord-005646-xhx9pzhj 4138 35 21 21 CD cord-005646-xhx9pzhj 4138 36 month month NN cord-005646-xhx9pzhj 4138 37 period period NN cord-005646-xhx9pzhj 4138 38 from from IN cord-005646-xhx9pzhj 4138 39 May May NNP cord-005646-xhx9pzhj 4138 40 1994 1994 CD cord-005646-xhx9pzhj 4138 41 to to IN cord-005646-xhx9pzhj 4138 42 January January NNP cord-005646-xhx9pzhj 4138 43 1996 1996 CD cord-005646-xhx9pzhj 4138 44 . . . cord-005646-xhx9pzhj 4139 1 The the DT cord-005646-xhx9pzhj 4139 2 9 9 CD cord-005646-xhx9pzhj 4139 3 girls girl NNS cord-005646-xhx9pzhj 4139 4 and and CC cord-005646-xhx9pzhj 4139 5 15 15 CD cord-005646-xhx9pzhj 4139 6 boys boy NNS cord-005646-xhx9pzhj 4139 7 were be VBD cord-005646-xhx9pzhj 4139 8 aged age VBN cord-005646-xhx9pzhj 4139 9 from from IN cord-005646-xhx9pzhj 4139 10 1 1 CD cord-005646-xhx9pzhj 4139 11 day day NN cord-005646-xhx9pzhj 4139 12 to to IN cord-005646-xhx9pzhj 4139 13 15 15 CD cord-005646-xhx9pzhj 4139 14 ½ ½ CD cord-005646-xhx9pzhj 4139 15 years year NNS cord-005646-xhx9pzhj 4139 16 ( ( -LRB- cord-005646-xhx9pzhj 4139 17 median median NN cord-005646-xhx9pzhj 4139 18 4½ 4½ CD cord-005646-xhx9pzhj 4139 19 years year NNS cord-005646-xhx9pzhj 4139 20 ) ) -RRB- cord-005646-xhx9pzhj 4139 21 and and CC cord-005646-xhx9pzhj 4139 22 weighed weigh VBD cord-005646-xhx9pzhj 4139 23 between between IN cord-005646-xhx9pzhj 4139 24 2,5 2,5 CD cord-005646-xhx9pzhj 4139 25 and and CC cord-005646-xhx9pzhj 4139 26 85 85 CD cord-005646-xhx9pzhj 4139 27 kg kg NNS cord-005646-xhx9pzhj 4139 28 ( ( -LRB- cord-005646-xhx9pzhj 4139 29 median median NN cord-005646-xhx9pzhj 4139 30 17.75 17.75 CD cord-005646-xhx9pzhj 4139 31 kg kg NNP cord-005646-xhx9pzhj 4139 32 ) ) -RRB- cord-005646-xhx9pzhj 4139 33 . . . cord-005646-xhx9pzhj 4140 1 Length length NN cord-005646-xhx9pzhj 4140 2 of of IN cord-005646-xhx9pzhj 4140 3 admission admission NN cord-005646-xhx9pzhj 4140 4 to to IN cord-005646-xhx9pzhj 4140 5 PICU PICU NNP cord-005646-xhx9pzhj 4140 6 was be VBD cord-005646-xhx9pzhj 4140 7 2 2 CD cord-005646-xhx9pzhj 4140 8 to to IN cord-005646-xhx9pzhj 4140 9 47 47 CD cord-005646-xhx9pzhj 4140 10 days day NNS cord-005646-xhx9pzhj 4140 11 ( ( -LRB- cord-005646-xhx9pzhj 4140 12 median median JJ cord-005646-xhx9pzhj 4140 13 9 9 CD cord-005646-xhx9pzhj 4140 14 days day NNS cord-005646-xhx9pzhj 4140 15 ) ) -RRB- cord-005646-xhx9pzhj 4140 16 . . . cord-005646-xhx9pzhj 4141 1 Sepsis sepsis NN cord-005646-xhx9pzhj 4141 2 syndrome syndrome NN cord-005646-xhx9pzhj 4141 3 was be VBD cord-005646-xhx9pzhj 4141 4 diagnosed diagnose VBN cord-005646-xhx9pzhj 4141 5 in in IN cord-005646-xhx9pzhj 4141 6 11 11 CD cord-005646-xhx9pzhj 4141 7 cases case NNS cord-005646-xhx9pzhj 4141 8 : : : cord-005646-xhx9pzhj 4141 9 4 4 CD cord-005646-xhx9pzhj 4141 10 of of IN cord-005646-xhx9pzhj 4141 11 these these DT cord-005646-xhx9pzhj 4141 12 had have VBD cord-005646-xhx9pzhj 4141 13 bowel bowel NN cord-005646-xhx9pzhj 4141 14 necrosis necrosis NN cord-005646-xhx9pzhj 4141 15 and and CC cord-005646-xhx9pzhj 4141 16 3 3 CD cord-005646-xhx9pzhj 4141 17 meningoceccal meningoceccal JJ cord-005646-xhx9pzhj 4141 18 disease disease NN cord-005646-xhx9pzhj 4141 19 . . . cord-005646-xhx9pzhj 4142 1 Eight eight CD cord-005646-xhx9pzhj 4142 2 patients patient NNS cord-005646-xhx9pzhj 4142 3 had have VBD cord-005646-xhx9pzhj 4142 4 an an DT cord-005646-xhx9pzhj 4142 5 underlying underlie VBG cord-005646-xhx9pzhj 4142 6 haematological haematological NN cord-005646-xhx9pzhj 4142 7 , , , cord-005646-xhx9pzhj 4142 8 oncolngical oncolngical JJ cord-005646-xhx9pzhj 4142 9 or or CC cord-005646-xhx9pzhj 4142 10 immune immune JJ cord-005646-xhx9pzhj 4142 11 disorder disorder NN cord-005646-xhx9pzhj 4142 12 . . . cord-005646-xhx9pzhj 4143 1 The the DT cord-005646-xhx9pzhj 4143 2 remaining remain VBG cord-005646-xhx9pzhj 4143 3 children child NNS cord-005646-xhx9pzhj 4143 4 had have VBD cord-005646-xhx9pzhj 4143 5 inborn inborn JJ cord-005646-xhx9pzhj 4143 6 errors error NNS cord-005646-xhx9pzhj 4143 7 of of IN cord-005646-xhx9pzhj 4143 8 metabolism metabolism NN cord-005646-xhx9pzhj 4143 9 ( ( -LRB- cord-005646-xhx9pzhj 4143 10 2 2 CD cord-005646-xhx9pzhj 4143 11 ) ) -RRB- cord-005646-xhx9pzhj 4143 12 , , , cord-005646-xhx9pzhj 4143 13 nephrotic nephrotic JJ cord-005646-xhx9pzhj 4143 14 syndrome syndrome NN cord-005646-xhx9pzhj 4143 15 ( ( -LRB- cord-005646-xhx9pzhj 4143 16 2 2 CD cord-005646-xhx9pzhj 4143 17 ) ) -RRB- cord-005646-xhx9pzhj 4143 18 , , , cord-005646-xhx9pzhj 4143 19 or or CC cord-005646-xhx9pzhj 4143 20 cardiac cardiac JJ cord-005646-xhx9pzhj 4143 21 failure failure NN cord-005646-xhx9pzhj 4143 22 ( ( -LRB- cord-005646-xhx9pzhj 4143 23 1 1 CD cord-005646-xhx9pzhj 4143 24 ) ) -RRB- cord-005646-xhx9pzhj 4143 25 . . . cord-005646-xhx9pzhj 4144 1 CVVH CVVH NNP cord-005646-xhx9pzhj 4144 2 was be VBD cord-005646-xhx9pzhj 4144 3 instituted institute VBN cord-005646-xhx9pzhj 4144 4 for for IN cord-005646-xhx9pzhj 4144 5 a a DT cord-005646-xhx9pzhj 4144 6 variety variety NN cord-005646-xhx9pzhj 4144 7 of of IN cord-005646-xhx9pzhj 4144 8 reasons reason NNS cord-005646-xhx9pzhj 4144 9 . . . cord-005646-xhx9pzhj 4145 1 Muttiorgan Muttiorgan NNP cord-005646-xhx9pzhj 4145 2 dysfunction dysfunction NN cord-005646-xhx9pzhj 4145 3 was be VBD cord-005646-xhx9pzhj 4145 4 present present JJ cord-005646-xhx9pzhj 4145 5 in in IN cord-005646-xhx9pzhj 4145 6 46 46 CD cord-005646-xhx9pzhj 4145 7 % % NN cord-005646-xhx9pzhj 4145 8 of of IN cord-005646-xhx9pzhj 4145 9 patients patient NNS cord-005646-xhx9pzhj 4145 10 , , , cord-005646-xhx9pzhj 4145 11 29 29 CD cord-005646-xhx9pzhj 4145 12 % % NN cord-005646-xhx9pzhj 4145 13 had have VBD cord-005646-xhx9pzhj 4145 14 acute acute JJ cord-005646-xhx9pzhj 4145 15 renal renal JJ cord-005646-xhx9pzhj 4145 16 failure failure NN cord-005646-xhx9pzhj 4145 17 , , , cord-005646-xhx9pzhj 4145 18 12.5 12.5 CD cord-005646-xhx9pzhj 4145 19 % % NN cord-005646-xhx9pzhj 4145 20 tumour tumour NN cord-005646-xhx9pzhj 4145 21 lysis lysis NN cord-005646-xhx9pzhj 4145 22 syndrome syndrome NN cord-005646-xhx9pzhj 4145 23 , , , cord-005646-xhx9pzhj 4145 24 8.5 8.5 CD cord-005646-xhx9pzhj 4145 25 % % NN cord-005646-xhx9pzhj 4145 26 uncontrollable uncontrollable JJ cord-005646-xhx9pzhj 4145 27 metabolic metabolic JJ cord-005646-xhx9pzhj 4145 28 acidosis acidosis NN cord-005646-xhx9pzhj 4145 29 with with IN cord-005646-xhx9pzhj 4145 30 hyperammoneemia hyperammoneemia NN cord-005646-xhx9pzhj 4145 31 and and CC cord-005646-xhx9pzhj 4145 32 4 4 CD cord-005646-xhx9pzhj 4145 33 % % NN cord-005646-xhx9pzhj 4145 34 required require VBN cord-005646-xhx9pzhj 4145 35 fluid fluid JJ cord-005646-xhx9pzhj 4145 36 management management NN cord-005646-xhx9pzhj 4145 37 . . . cord-005646-xhx9pzhj 4146 1 Treatment treatment NN cord-005646-xhx9pzhj 4146 2 was be VBD cord-005646-xhx9pzhj 4146 3 continued continue VBN cord-005646-xhx9pzhj 4146 4 for for IN cord-005646-xhx9pzhj 4146 5 between between IN cord-005646-xhx9pzhj 4146 6 4 4 CD cord-005646-xhx9pzhj 4146 7 hours hour NNS cord-005646-xhx9pzhj 4146 8 and and CC cord-005646-xhx9pzhj 4146 9 26 26 CD cord-005646-xhx9pzhj 4146 10 days day NNS cord-005646-xhx9pzhj 4146 11 ( ( -LRB- cord-005646-xhx9pzhj 4146 12 median median NN cord-005646-xhx9pzhj 4146 13 4½ 4½ CD cord-005646-xhx9pzhj 4146 14 days day NNS cord-005646-xhx9pzhj 4146 15 ) ) -RRB- cord-005646-xhx9pzhj 4146 16 . . . cord-005646-xhx9pzhj 4147 1 Haemofiltration Haemofiltration NNP cord-005646-xhx9pzhj 4147 2 was be VBD cord-005646-xhx9pzhj 4147 3 successful successful JJ cord-005646-xhx9pzhj 4147 4 in in IN cord-005646-xhx9pzhj 4147 5 achieving achieve VBG cord-005646-xhx9pzhj 4147 6 its -PRON- PRP$ cord-005646-xhx9pzhj 4147 7 desired desire VBN cord-005646-xhx9pzhj 4147 8 effect effect NN cord-005646-xhx9pzhj 4147 9 in in IN cord-005646-xhx9pzhj 4147 10 all all DT cord-005646-xhx9pzhj 4147 11 except except IN cord-005646-xhx9pzhj 4147 12 one one CD cord-005646-xhx9pzhj 4147 13 patient patient NN cord-005646-xhx9pzhj 4147 14 . . . cord-005646-xhx9pzhj 4148 1 87.5 87.5 CD cord-005646-xhx9pzhj 4148 2 % % NN cord-005646-xhx9pzhj 4148 3 of of IN cord-005646-xhx9pzhj 4148 4 children child NNS cord-005646-xhx9pzhj 4148 5 with with IN cord-005646-xhx9pzhj 4148 6 haematological haematological JJ cord-005646-xhx9pzhj 4148 7 , , , cord-005646-xhx9pzhj 4148 8 ontological ontological JJ cord-005646-xhx9pzhj 4148 9 or or CC cord-005646-xhx9pzhj 4148 10 immune immune JJ cord-005646-xhx9pzhj 4148 11 disorders disorder NNS cord-005646-xhx9pzhj 4148 12 died die VBD cord-005646-xhx9pzhj 4148 13 despite despite IN cord-005646-xhx9pzhj 4148 14 successful successful JJ cord-005646-xhx9pzhj 4148 15 haemofiltration haemofiltration NN cord-005646-xhx9pzhj 4148 16 . . . cord-005646-xhx9pzhj 4149 1 Survival survival NN cord-005646-xhx9pzhj 4149 2 was be VBD cord-005646-xhx9pzhj 4149 3 higher high JJR cord-005646-xhx9pzhj 4149 4 in in IN cord-005646-xhx9pzhj 4149 5 cases case NNS cord-005646-xhx9pzhj 4149 6 of of IN cord-005646-xhx9pzhj 4149 7 septicaemia septicaemia NN cord-005646-xhx9pzhj 4149 8 ( ( -LRB- cord-005646-xhx9pzhj 4149 9 45.5 45.5 CD cord-005646-xhx9pzhj 4149 10 % % NN cord-005646-xhx9pzhj 4149 11 ) ) -RRB- cord-005646-xhx9pzhj 4149 12 , , , cord-005646-xhx9pzhj 4149 13 nephrotic nephrotic JJ cord-005646-xhx9pzhj 4149 14 syndrome syndrome NN cord-005646-xhx9pzhj 4149 15 ( ( -LRB- cord-005646-xhx9pzhj 4149 16 50 50 CD cord-005646-xhx9pzhj 4149 17 % % NN cord-005646-xhx9pzhj 4149 18 ) ) -RRB- cord-005646-xhx9pzhj 4149 19 and and CC cord-005646-xhx9pzhj 4149 20 errors error NNS cord-005646-xhx9pzhj 4149 21 of of IN cord-005646-xhx9pzhj 4149 22 metabolism metabolism NN cord-005646-xhx9pzhj 4149 23 ( ( -LRB- cord-005646-xhx9pzhj 4149 24 50 50 CD cord-005646-xhx9pzhj 4149 25 % % NN cord-005646-xhx9pzhj 4149 26 ) ) -RRB- cord-005646-xhx9pzhj 4149 27 . . . cord-005646-xhx9pzhj 4150 1 Overall overall JJ cord-005646-xhx9pzhj 4150 2 mortality mortality NN cord-005646-xhx9pzhj 4150 3 was be VBD cord-005646-xhx9pzhj 4150 4 62.5 62.5 CD cord-005646-xhx9pzhj 4150 5 % % NN cord-005646-xhx9pzhj 4150 6 . . . cord-005646-xhx9pzhj 4151 1 This this DT cord-005646-xhx9pzhj 4151 2 was be VBD cord-005646-xhx9pzhj 4151 3 attributed attribute VBN cord-005646-xhx9pzhj 4151 4 to to IN cord-005646-xhx9pzhj 4151 5 the the DT cord-005646-xhx9pzhj 4151 6 severity severity NN cord-005646-xhx9pzhj 4151 7 of of IN cord-005646-xhx9pzhj 4151 8 the the DT cord-005646-xhx9pzhj 4151 9 underlying underlie VBG cord-005646-xhx9pzhj 4151 10 disease disease NN cord-005646-xhx9pzhj 4151 11 process process NN cord-005646-xhx9pzhj 4151 12 rather rather RB cord-005646-xhx9pzhj 4151 13 than than IN cord-005646-xhx9pzhj 4151 14 the the DT cord-005646-xhx9pzhj 4151 15 effectiveness effectiveness NN cord-005646-xhx9pzhj 4151 16 of of IN cord-005646-xhx9pzhj 4151 17 CVVH CVVH NNP cord-005646-xhx9pzhj 4151 18 as as IN cord-005646-xhx9pzhj 4151 19 a a DT cord-005646-xhx9pzhj 4151 20 renal renal JJ cord-005646-xhx9pzhj 4151 21 replacement replacement NN cord-005646-xhx9pzhj 4151 22 therapy therapy NN cord-005646-xhx9pzhj 4151 23 . . . cord-005646-xhx9pzhj 4152 1 Asynchronous asynchronous JJ cord-005646-xhx9pzhj 4152 2 defibrillation defibrillation NN cord-005646-xhx9pzhj 4152 3 and and CC cord-005646-xhx9pzhj 4152 4 synchronized synchronize VBN cord-005646-xhx9pzhj 4152 5 cardioversion cardioversion NN cord-005646-xhx9pzhj 4152 6 deliver deliver VBP cord-005646-xhx9pzhj 4152 7 direct direct JJ cord-005646-xhx9pzhj 4152 8 currents current NNS cord-005646-xhx9pzhj 4152 9 of of IN cord-005646-xhx9pzhj 4152 10 high high JJ cord-005646-xhx9pzhj 4152 11 amplitude amplitude NN cord-005646-xhx9pzhj 4152 12 through through IN cord-005646-xhx9pzhj 4152 13 the the DT cord-005646-xhx9pzhj 4152 14 chest chest NN cord-005646-xhx9pzhj 4152 15 , , , cord-005646-xhx9pzhj 4152 16 to to TO cord-005646-xhx9pzhj 4152 17 stop stop VB cord-005646-xhx9pzhj 4152 18 ventricular ventricular JJ cord-005646-xhx9pzhj 4152 19 fibrillation fibrillation NN cord-005646-xhx9pzhj 4152 20 or or CC cord-005646-xhx9pzhj 4152 21 to to TO cord-005646-xhx9pzhj 4152 22 convert convert VB cord-005646-xhx9pzhj 4152 23 life life NN cord-005646-xhx9pzhj 4152 24 - - HYPH cord-005646-xhx9pzhj 4152 25 threatening threaten VBG cord-005646-xhx9pzhj 4152 26 arrhythmias arrhythmia NNS cord-005646-xhx9pzhj 4152 27 . . . cord-005646-xhx9pzhj 4153 1 Since since IN cord-005646-xhx9pzhj 4153 2 the the DT cord-005646-xhx9pzhj 4153 3 human human JJ cord-005646-xhx9pzhj 4153 4 body body NN cord-005646-xhx9pzhj 4153 5 is be VBZ cord-005646-xhx9pzhj 4153 6 partially partially RB cord-005646-xhx9pzhj 4153 7 conductant conductant JJ cord-005646-xhx9pzhj 4153 8 , , , cord-005646-xhx9pzhj 4153 9 it -PRON- PRP cord-005646-xhx9pzhj 4153 10 should should MD cord-005646-xhx9pzhj 4153 11 be be VB cord-005646-xhx9pzhj 4153 12 possible possible JJ cord-005646-xhx9pzhj 4153 13 that that IN cord-005646-xhx9pzhj 4153 14 after after IN cord-005646-xhx9pzhj 4153 15 a a DT cord-005646-xhx9pzhj 4153 16 brief brief JJ cord-005646-xhx9pzhj 4153 17 delay delay NN cord-005646-xhx9pzhj 4153 18 of of IN cord-005646-xhx9pzhj 4153 19 time time NN cord-005646-xhx9pzhj 4153 20 , , , cord-005646-xhx9pzhj 4153 21 a a DT cord-005646-xhx9pzhj 4153 22 derivation derivation NN cord-005646-xhx9pzhj 4153 23 of of IN cord-005646-xhx9pzhj 4153 24 this this DT cord-005646-xhx9pzhj 4153 25 monophasic monophasic JJ cord-005646-xhx9pzhj 4153 26 defibrillation defibrillation NN cord-005646-xhx9pzhj 4153 27 pulse pulse NN cord-005646-xhx9pzhj 4153 28 is be VBZ cord-005646-xhx9pzhj 4153 29 measurable measurable JJ cord-005646-xhx9pzhj 4153 30 in in IN cord-005646-xhx9pzhj 4153 31 regions region NNS cord-005646-xhx9pzhj 4153 32 of of IN cord-005646-xhx9pzhj 4153 33 the the DT cord-005646-xhx9pzhj 4153 34 defibrillated defibrillate VBN cord-005646-xhx9pzhj 4153 35 body body NN cord-005646-xhx9pzhj 4153 36 , , , cord-005646-xhx9pzhj 4153 37 other other JJ cord-005646-xhx9pzhj 4153 38 than than IN cord-005646-xhx9pzhj 4153 39 the the DT cord-005646-xhx9pzhj 4153 40 traject traject NN cord-005646-xhx9pzhj 4153 41 between between IN cord-005646-xhx9pzhj 4153 42 anodal anodal JJ cord-005646-xhx9pzhj 4153 43 ( ( -LRB- cord-005646-xhx9pzhj 4153 44 " " `` cord-005646-xhx9pzhj 4153 45 sternum sternum NN cord-005646-xhx9pzhj 4153 46 " " '' cord-005646-xhx9pzhj 4153 47 ) ) -RRB- cord-005646-xhx9pzhj 4153 48 and and CC cord-005646-xhx9pzhj 4153 49 cathodaI cathodaI NNP cord-005646-xhx9pzhj 4153 50 ( ( -LRB- cord-005646-xhx9pzhj 4153 51 " " `` cord-005646-xhx9pzhj 4153 52 ape~ ape~ CD cord-005646-xhx9pzhj 4153 53 ; ; : cord-005646-xhx9pzhj 4153 54 " " '' cord-005646-xhx9pzhj 4153 55 ) ) -RRB- cord-005646-xhx9pzhj 4153 56 paddles paddle NNS cord-005646-xhx9pzhj 4153 57 . . . cord-005646-xhx9pzhj 4154 1 One one PRP cord-005646-xhx9pzhj 4154 2 could could MD cord-005646-xhx9pzhj 4154 3 also also RB cord-005646-xhx9pzhj 4154 4 estimate estimate VB cord-005646-xhx9pzhj 4154 5 that that IN cord-005646-xhx9pzhj 4154 6 health health NN cord-005646-xhx9pzhj 4154 7 care care NN cord-005646-xhx9pzhj 4154 8 personnel personnel NNS cord-005646-xhx9pzhj 4154 9 in in IN cord-005646-xhx9pzhj 4154 10 the the DT cord-005646-xhx9pzhj 4154 11 immediate immediate JJ cord-005646-xhx9pzhj 4154 12 environment environment NN cord-005646-xhx9pzhj 4154 13 of of IN cord-005646-xhx9pzhj 4154 14 defibrillatoty defibrillatoty NNP cord-005646-xhx9pzhj 4154 15 shocks shock NNS cord-005646-xhx9pzhj 4154 16 , , , cord-005646-xhx9pzhj 4154 17 are be VBP cord-005646-xhx9pzhj 4154 18 always always RB cord-005646-xhx9pzhj 4154 19 at at IN cord-005646-xhx9pzhj 4154 20 risk risk NN cord-005646-xhx9pzhj 4154 21 to to IN cord-005646-xhx9pzhj 4154 22 possible possible JJ cord-005646-xhx9pzhj 4154 23 electric electric JJ cord-005646-xhx9pzhj 4154 24 injury injury NN cord-005646-xhx9pzhj 4154 25 . . . cord-005646-xhx9pzhj 4155 1 Accidents accident NNS cord-005646-xhx9pzhj 4155 2 might may MD cord-005646-xhx9pzhj 4155 3 occur occur VB cord-005646-xhx9pzhj 4155 4 when when WRB cord-005646-xhx9pzhj 4155 5 health health NN cord-005646-xhx9pzhj 4155 6 care care NN cord-005646-xhx9pzhj 4155 7 personnel personnel NNS cord-005646-xhx9pzhj 4155 8 do do VBP cord-005646-xhx9pzhj 4155 9 not not RB cord-005646-xhx9pzhj 4155 10 stand stand VB cord-005646-xhx9pzhj 4155 11 clear clear JJ cord-005646-xhx9pzhj 4155 12 from from IN cord-005646-xhx9pzhj 4155 13 the the DT cord-005646-xhx9pzhj 4155 14 patient patient NN cord-005646-xhx9pzhj 4155 15 during during IN cord-005646-xhx9pzhj 4155 16 firing fire VBG cord-005646-xhx9pzhj 4155 17 and and CC cord-005646-xhx9pzhj 4155 18 create create VB cord-005646-xhx9pzhj 4155 19 an an DT cord-005646-xhx9pzhj 4155 20 additional additional JJ cord-005646-xhx9pzhj 4155 21 electric electric JJ cord-005646-xhx9pzhj 4155 22 path path NN cord-005646-xhx9pzhj 4155 23 from from IN cord-005646-xhx9pzhj 4155 24 this this DT cord-005646-xhx9pzhj 4155 25 patient patient NN cord-005646-xhx9pzhj 4155 26 through through IN cord-005646-xhx9pzhj 4155 27 their -PRON- PRP$ cord-005646-xhx9pzhj 4155 28 own own JJ cord-005646-xhx9pzhj 4155 29 body body NN cord-005646-xhx9pzhj 4155 30 . . . cord-005646-xhx9pzhj 4156 1 Most most RBS cord-005646-xhx9pzhj 4156 2 likely likely JJ cord-005646-xhx9pzhj 4156 3 , , , cord-005646-xhx9pzhj 4156 4 the the DT cord-005646-xhx9pzhj 4156 5 nonisolated nonisolate VBN cord-005646-xhx9pzhj 4156 6 parts part NNS cord-005646-xhx9pzhj 4156 7 creating create VBG cord-005646-xhx9pzhj 4156 8 a a DT cord-005646-xhx9pzhj 4156 9 transversal transversal JJ cord-005646-xhx9pzhj 4156 10 eIectric eIectric NNP cord-005646-xhx9pzhj 4156 11 path path NN cord-005646-xhx9pzhj 4156 12 , , , cord-005646-xhx9pzhj 4156 13 will will MD cord-005646-xhx9pzhj 4156 14 be be VB cord-005646-xhx9pzhj 4156 15 the the DT cord-005646-xhx9pzhj 4156 16 hands hand NNS cord-005646-xhx9pzhj 4156 17 of of IN cord-005646-xhx9pzhj 4156 18 the the DT cord-005646-xhx9pzhj 4156 19 caretaker caretaker NN cord-005646-xhx9pzhj 4156 20 . . . cord-005646-xhx9pzhj 4157 1 Since since IN cord-005646-xhx9pzhj 4157 2 defibrillation defibrillation NN cord-005646-xhx9pzhj 4157 3 generates generate VBZ cord-005646-xhx9pzhj 4157 4 touch touch NN cord-005646-xhx9pzhj 4157 5 voltages voltage VBZ cord-005646-xhx9pzhj 4157 6 up up RP cord-005646-xhx9pzhj 4157 7 to to TO cord-005646-xhx9pzhj 4157 8 5000 5000 CD cord-005646-xhx9pzhj 4157 9 V v NN cord-005646-xhx9pzhj 4157 10 and and CC cord-005646-xhx9pzhj 4157 11 60 60 CD cord-005646-xhx9pzhj 4157 12 - - SYM cord-005646-xhx9pzhj 4157 13 70 70 CD cord-005646-xhx9pzhj 4157 14 A a NN cord-005646-xhx9pzhj 4157 15 in in IN cord-005646-xhx9pzhj 4157 16 veD ved NN cord-005646-xhx9pzhj 4157 17 , , , cord-005646-xhx9pzhj 4157 18 short short JJ cord-005646-xhx9pzhj 4157 19 delay delay NN cord-005646-xhx9pzhj 4157 20 's 's POS cord-005646-xhx9pzhj 4157 21 ( ( -LRB- cord-005646-xhx9pzhj 4157 22 5 5 CD cord-005646-xhx9pzhj 4157 23 to to TO cord-005646-xhx9pzhj 4157 24 10 10 CD cord-005646-xhx9pzhj 4157 25 millisec millisec NNS cord-005646-xhx9pzhj 4157 26 ) ) -RRB- cord-005646-xhx9pzhj 4157 27 , , , cord-005646-xhx9pzhj 4157 28 the the DT cord-005646-xhx9pzhj 4157 29 total total JJ cord-005646-xhx9pzhj 4157 30 body body NN cord-005646-xhx9pzhj 4157 31 resistance resistance NN cord-005646-xhx9pzhj 4157 32 during during IN cord-005646-xhx9pzhj 4157 33 skin skin NN cord-005646-xhx9pzhj 4157 34 to to IN cord-005646-xhx9pzhj 4157 35 skin skin NN cord-005646-xhx9pzhj 4157 36 or or CC cord-005646-xhx9pzhj 4157 37 skin skin NN cord-005646-xhx9pzhj 4157 38 to to TO cord-005646-xhx9pzhj 4157 39 paddle paddle VB cord-005646-xhx9pzhj 4157 40 contact contact NN cord-005646-xhx9pzhj 4157 41 , , , cord-005646-xhx9pzhj 4157 42 is be VBZ cord-005646-xhx9pzhj 4157 43 calculated calculate VBN cord-005646-xhx9pzhj 4157 44 to to TO cord-005646-xhx9pzhj 4157 45 be be VB cord-005646-xhx9pzhj 4157 46 as as IN cord-005646-xhx9pzhj 4157 47 [ [ -LRB- cord-005646-xhx9pzhj 4157 48 ow ow UH cord-005646-xhx9pzhj 4157 49 as as IN cord-005646-xhx9pzhj 4157 50 750 750 CD cord-005646-xhx9pzhj 4157 51 ohm ohm NN cord-005646-xhx9pzhj 4157 52 ( ( -LRB- cord-005646-xhx9pzhj 4157 53 percentile percentile JJ cord-005646-xhx9pzhj 4157 54 tank tank NN cord-005646-xhx9pzhj 4157 55 50 50 CD cord-005646-xhx9pzhj 4157 56 for for IN cord-005646-xhx9pzhj 4157 57 the the DT cord-005646-xhx9pzhj 4157 58 entire entire JJ cord-005646-xhx9pzhj 4157 59 population population NN cord-005646-xhx9pzhj 4157 60 ) ) -RRB- cord-005646-xhx9pzhj 4157 61 . . . cord-005646-xhx9pzhj 4158 1 An an DT cord-005646-xhx9pzhj 4158 2 experimental experimental JJ cord-005646-xhx9pzhj 4158 3 protocol protocol NN cord-005646-xhx9pzhj 4158 4 was be VBD cord-005646-xhx9pzhj 4158 5 developed develop VBN cord-005646-xhx9pzhj 4158 6 to to TO cord-005646-xhx9pzhj 4158 7 evaluate evaluate VB cord-005646-xhx9pzhj 4158 8 the the DT cord-005646-xhx9pzhj 4158 9 conducted conduct VBN cord-005646-xhx9pzhj 4158 10 currents current NNS cord-005646-xhx9pzhj 4158 11 during during IN cord-005646-xhx9pzhj 4158 12 defibrillation defibrillation NN cord-005646-xhx9pzhj 4158 13 . . . cord-005646-xhx9pzhj 4159 1 Mature mature JJ cord-005646-xhx9pzhj 4159 2 pigs pig NNS cord-005646-xhx9pzhj 4159 3 with with IN cord-005646-xhx9pzhj 4159 4 a a DT cord-005646-xhx9pzhj 4159 5 weight weight NN cord-005646-xhx9pzhj 4159 6 of of IN cord-005646-xhx9pzhj 4159 7 100 100 CD cord-005646-xhx9pzhj 4159 8 up up IN cord-005646-xhx9pzhj 4159 9 to to TO cord-005646-xhx9pzhj 4159 10 150 150 CD cord-005646-xhx9pzhj 4159 11 kg kg NNS cord-005646-xhx9pzhj 4159 12 . . . cord-005646-xhx9pzhj 4159 13 were be VBD cord-005646-xhx9pzhj 4159 14 used use VBN cord-005646-xhx9pzhj 4159 15 as as IN cord-005646-xhx9pzhj 4159 16 animal animal NN cord-005646-xhx9pzhj 4159 17 models model NNS cord-005646-xhx9pzhj 4159 18 . . . cord-005646-xhx9pzhj 4160 1 The the DT cord-005646-xhx9pzhj 4160 2 : : : cord-005646-xhx9pzhj 4160 3 , , , cord-005646-xhx9pzhj 4160 4 , , , cord-005646-xhx9pzhj 4160 5 had have VBD cord-005646-xhx9pzhj 4160 6 barbiturate barbiturate NN cord-005646-xhx9pzhj 4160 7 anaesthesia anaesthesia NN cord-005646-xhx9pzhj 4160 8 , , , cord-005646-xhx9pzhj 4160 9 inotropic inotropic NNP cord-005646-xhx9pzhj 4160 10 support support NN cord-005646-xhx9pzhj 4160 11 with with IN cord-005646-xhx9pzhj 4160 12 dobutamine dobutamine NN cord-005646-xhx9pzhj 4160 13 at at IN cord-005646-xhx9pzhj 4160 14 l l NN cord-005646-xhx9pzhj 4160 15 0 0 CD cord-005646-xhx9pzhj 4160 16 micmgrams micmgrams NNP cord-005646-xhx9pzhj 4160 17 / / SYM cord-005646-xhx9pzhj 4160 18 kg kg CC cord-005646-xhx9pzhj 4160 19 bodyweight bodyweight NN cord-005646-xhx9pzhj 4160 20 and and CC cord-005646-xhx9pzhj 4160 21 all all DT cord-005646-xhx9pzhj 4160 22 had have VBD cord-005646-xhx9pzhj 4160 23 a a DT cord-005646-xhx9pzhj 4160 24 sinasat sinasat JJ cord-005646-xhx9pzhj 4160 25 rhythm rhythm NN cord-005646-xhx9pzhj 4160 26 at at IN cord-005646-xhx9pzhj 4160 27 the the DT cord-005646-xhx9pzhj 4160 28 begining begining NN cord-005646-xhx9pzhj 4160 29 of of IN cord-005646-xhx9pzhj 4160 30 the the DT cord-005646-xhx9pzhj 4160 31 test test NN cord-005646-xhx9pzhj 4160 32 - - HYPH cord-005646-xhx9pzhj 4160 33 rounds round NNS cord-005646-xhx9pzhj 4160 34 . . . cord-005646-xhx9pzhj 4161 1 Synchronized synchronized JJ cord-005646-xhx9pzhj 4161 2 defibrillation defibrillation NN cord-005646-xhx9pzhj 4161 3 at at IN cord-005646-xhx9pzhj 4161 4 100 100 CD cord-005646-xhx9pzhj 4161 5 J J NNP cord-005646-xhx9pzhj 4161 6 ( ( -LRB- cord-005646-xhx9pzhj 4161 7 approx approx NN cord-005646-xhx9pzhj 4161 8 . . . cord-005646-xhx9pzhj 4162 1 0.75 0.75 CD cord-005646-xhx9pzhj 4162 2 J J NNP cord-005646-xhx9pzhj 4162 3 / / SYM cord-005646-xhx9pzhj 4162 4 kg kg NNP cord-005646-xhx9pzhj 4162 5 ) ) -RRB- cord-005646-xhx9pzhj 4162 6 and and CC cord-005646-xhx9pzhj 4162 7 asynchronized asynchronize VBD cord-005646-xhx9pzhj 4162 8 -at -at CD cord-005646-xhx9pzhj 4162 9 360 360 CD cord-005646-xhx9pzhj 4162 10 J J NNP cord-005646-xhx9pzhj 4162 11 ( ( -LRB- cord-005646-xhx9pzhj 4162 12 whenever whenever WRB cord-005646-xhx9pzhj 4162 13 ventricular ventricular JJ cord-005646-xhx9pzhj 4162 14 fibrillation fibrillation NN cord-005646-xhx9pzhj 4162 15 or or CC cord-005646-xhx9pzhj 4162 16 ventricular ventricular JJ cord-005646-xhx9pzhj 4162 17 tachycardia tachycardia NN cord-005646-xhx9pzhj 4162 18 occurred occur VBD cord-005646-xhx9pzhj 4162 19 ) ) -RRB- cord-005646-xhx9pzhj 4162 20 , , , cord-005646-xhx9pzhj 4162 21 were be VBD cord-005646-xhx9pzhj 4162 22 attempted attempt VBN cord-005646-xhx9pzhj 4162 23 , , , cord-005646-xhx9pzhj 4162 24 through through IN cord-005646-xhx9pzhj 4162 25 latero latero JJ cord-005646-xhx9pzhj 4162 26 - - HYPH cord-005646-xhx9pzhj 4162 27 lateral lateral JJ cord-005646-xhx9pzhj 4162 28 placed place VBN cord-005646-xhx9pzhj 4162 29 and and CC cord-005646-xhx9pzhj 4162 30 firmly firmly RB cord-005646-xhx9pzhj 4162 31 pressed press VBD cord-005646-xhx9pzhj 4162 32 defibrillation defibrillation NN cord-005646-xhx9pzhj 4162 33 paddles paddle NNS cord-005646-xhx9pzhj 4162 34 and/or and/or CC cord-005646-xhx9pzhj 4162 35 adhesive adhesive JJ cord-005646-xhx9pzhj 4162 36 multi multi JJ cord-005646-xhx9pzhj 4162 37 - - JJ cord-005646-xhx9pzhj 4162 38 function function NN cord-005646-xhx9pzhj 4162 39 electrodes electrode NNS cord-005646-xhx9pzhj 4162 40 . . . cord-005646-xhx9pzhj 4163 1 Gel gel NN cord-005646-xhx9pzhj 4163 2 pads pad NNS cord-005646-xhx9pzhj 4163 3 were be VBD cord-005646-xhx9pzhj 4163 4 choosen choosen VBN cord-005646-xhx9pzhj 4163 5 as as IN cord-005646-xhx9pzhj 4163 6 contactmedium contactmedium NNP cord-005646-xhx9pzhj 4163 7 to to TO cord-005646-xhx9pzhj 4163 8 cross cross VB cord-005646-xhx9pzhj 4163 9 the the DT cord-005646-xhx9pzhj 4163 10 skinpaddle skinpaddle NNP cord-005646-xhx9pzhj 4163 11 barrier barrier NN cord-005646-xhx9pzhj 4163 12 . . . cord-005646-xhx9pzhj 4164 1 Subdermal subdermal JJ cord-005646-xhx9pzhj 4164 2 electro electro JJ cord-005646-xhx9pzhj 4164 3 - - HYPH cord-005646-xhx9pzhj 4164 4 myography myography NN cord-005646-xhx9pzhj 4164 5 needle needle NN cord-005646-xhx9pzhj 4164 6 electrodes electrode NNS cord-005646-xhx9pzhj 4164 7 were be VBD cord-005646-xhx9pzhj 4164 8 put put VBN cord-005646-xhx9pzhj 4164 9 at at IN cord-005646-xhx9pzhj 4164 10 different different JJ cord-005646-xhx9pzhj 4164 11 parts part NNS cord-005646-xhx9pzhj 4164 12 and and CC cord-005646-xhx9pzhj 4164 13 regions region NNS cord-005646-xhx9pzhj 4164 14 of of IN cord-005646-xhx9pzhj 4164 15 the the DT cord-005646-xhx9pzhj 4164 16 pig pig NN cord-005646-xhx9pzhj 4164 17 's 's POS cord-005646-xhx9pzhj 4164 18 body body NN cord-005646-xhx9pzhj 4164 19 , , , cord-005646-xhx9pzhj 4164 20 but but CC cord-005646-xhx9pzhj 4164 21 not not RB cord-005646-xhx9pzhj 4164 22 between between IN cord-005646-xhx9pzhj 4164 23 the the DT cord-005646-xhx9pzhj 4164 24 paddles paddle NNS cord-005646-xhx9pzhj 4164 25 . . . cord-005646-xhx9pzhj 4165 1 These these DT cord-005646-xhx9pzhj 4165 2 electrodes electrode NNS cord-005646-xhx9pzhj 4165 3 were be VBD cord-005646-xhx9pzhj 4165 4 coupled couple VBN cord-005646-xhx9pzhj 4165 5 to to IN cord-005646-xhx9pzhj 4165 6 a a DT cord-005646-xhx9pzhj 4165 7 resistance resistance NN cord-005646-xhx9pzhj 4165 8 device device NN cord-005646-xhx9pzhj 4165 9 of of IN cord-005646-xhx9pzhj 4165 10 800 800 CD cord-005646-xhx9pzhj 4165 11 ohm ohm CD cord-005646-xhx9pzhj 4165 12 and and CC cord-005646-xhx9pzhj 4165 13 a a DT cord-005646-xhx9pzhj 4165 14 measuring measure VBG cord-005646-xhx9pzhj 4165 15 computer computer NN cord-005646-xhx9pzhj 4165 16 . . . cord-005646-xhx9pzhj 4166 1 We -PRON- PRP cord-005646-xhx9pzhj 4166 2 measured measure VBD cord-005646-xhx9pzhj 4166 3 monophasic monophasic JJ cord-005646-xhx9pzhj 4166 4 and and CC cord-005646-xhx9pzhj 4166 5 low low JJ cord-005646-xhx9pzhj 4166 6 current current JJ cord-005646-xhx9pzhj 4166 7 pulses pulse VBZ cord-005646-xhx9pzhj 4166 8 up up RP cord-005646-xhx9pzhj 4166 9 to to IN cord-005646-xhx9pzhj 4166 10 0,10 0,10 XX cord-005646-xhx9pzhj 4167 1 A a DT cord-005646-xhx9pzhj 4167 2 during during IN cord-005646-xhx9pzhj 4167 3 the the DT cord-005646-xhx9pzhj 4167 4 defibrillation defibrillation NN cord-005646-xhx9pzhj 4167 5 burst burst VBD cord-005646-xhx9pzhj 4167 6 . . . cord-005646-xhx9pzhj 4168 1 Thus thus RB cord-005646-xhx9pzhj 4168 2 conducted conduct VBN cord-005646-xhx9pzhj 4168 3 currents current NNS cord-005646-xhx9pzhj 4168 4 are be VBP cord-005646-xhx9pzhj 4168 5 high high JJ cord-005646-xhx9pzhj 4168 6 enough enough RB cord-005646-xhx9pzhj 4168 7 to to TO cord-005646-xhx9pzhj 4168 8 produce produce VB cord-005646-xhx9pzhj 4168 9 accidental accidental JJ cord-005646-xhx9pzhj 4168 10 electric electric JJ cord-005646-xhx9pzhj 4168 11 shocks shock NNS cord-005646-xhx9pzhj 4168 12 when when WRB cord-005646-xhx9pzhj 4168 13 additional additional JJ cord-005646-xhx9pzhj 4168 14 electric electric JJ cord-005646-xhx9pzhj 4168 15 paths path NNS cord-005646-xhx9pzhj 4168 16 are be VBP cord-005646-xhx9pzhj 4168 17 created create VBN cord-005646-xhx9pzhj 4168 18 by by IN cord-005646-xhx9pzhj 4168 19 the the DT cord-005646-xhx9pzhj 4168 20 caretaker caretaker NN cord-005646-xhx9pzhj 4168 21 . . . cord-005646-xhx9pzhj 4169 1 " " `` cord-005646-xhx9pzhj 4169 2 llaese llaese NNP cord-005646-xhx9pzhj 4169 3 are be VBP cord-005646-xhx9pzhj 4169 4 usually usually RB cord-005646-xhx9pzhj 4169 5 harmless harmless JJ cord-005646-xhx9pzhj 4169 6 , , , cord-005646-xhx9pzhj 4169 7 but but CC cord-005646-xhx9pzhj 4169 8 in in IN cord-005646-xhx9pzhj 4169 9 some some DT cord-005646-xhx9pzhj 4169 10 " " `` cord-005646-xhx9pzhj 4169 11 worst bad JJS cord-005646-xhx9pzhj 4169 12 case case NN cord-005646-xhx9pzhj 4169 13 " " '' cord-005646-xhx9pzhj 4169 14 ( ( -LRB- cord-005646-xhx9pzhj 4169 15 wet wet JJ cord-005646-xhx9pzhj 4169 16 or or CC cord-005646-xhx9pzhj 4169 17 transpiring transpire VBG cord-005646-xhx9pzhj 4169 18 hands hand NNS cord-005646-xhx9pzhj 4169 19 , , , cord-005646-xhx9pzhj 4169 20 rings ring NNS cord-005646-xhx9pzhj 4169 21 , , , cord-005646-xhx9pzhj 4169 22 ... ... NFP cord-005646-xhx9pzhj 4169 23 ) ) -RRB- cord-005646-xhx9pzhj 4169 24 or or CC cord-005646-xhx9pzhj 4169 25 in in IN cord-005646-xhx9pzhj 4169 26 association association NN cord-005646-xhx9pzhj 4169 27 with with IN cord-005646-xhx9pzhj 4169 28 defectuous defectuous NNP cord-005646-xhx9pzhj 4169 29 equipment equipment NN cord-005646-xhx9pzhj 4169 30 , , , cord-005646-xhx9pzhj 4169 31 peak peak NN cord-005646-xhx9pzhj 4169 32 currents current NNS cord-005646-xhx9pzhj 4169 33 might may MD cord-005646-xhx9pzhj 4169 34 be be VB cord-005646-xhx9pzhj 4169 35 harmfull harmfull JJ cord-005646-xhx9pzhj 4169 36 , , , cord-005646-xhx9pzhj 4169 37 and and CC cord-005646-xhx9pzhj 4169 38 can can MD cord-005646-xhx9pzhj 4169 39 produce produce VB cord-005646-xhx9pzhj 4169 40 pain pain NN cord-005646-xhx9pzhj 4169 41 , , , cord-005646-xhx9pzhj 4169 42 bums bum NNS cord-005646-xhx9pzhj 4169 43 , , , cord-005646-xhx9pzhj 4169 44 apnae apnae NN cord-005646-xhx9pzhj 4169 45 or or CC cord-005646-xhx9pzhj 4169 46 cardiac cardiac JJ cord-005646-xhx9pzhj 4169 47 ( ( -LRB- cord-005646-xhx9pzhj 4169 48 transient transient JJ cord-005646-xhx9pzhj 4169 49 or or CC cord-005646-xhx9pzhj 4169 50 persistant persistant JJ cord-005646-xhx9pzhj 4169 51 ) ) -RRB- cord-005646-xhx9pzhj 4169 52 arrhythmias arrhythmias RB cord-005646-xhx9pzhj 4169 53 . . . cord-005646-xhx9pzhj 4170 1 Maria Maria NNP cord-005646-xhx9pzhj 4170 2 Skogbv Skogbv NNP cord-005646-xhx9pzhj 4170 3 . . . cord-005646-xhx9pzhj 4171 1 Karin Karin NNP cord-005646-xhx9pzhj 4171 2 Mellgren Mellgren NNP cord-005646-xhx9pzhj 4171 3 , , , cord-005646-xhx9pzhj 4171 4 Lars Lars NNP cord-005646-xhx9pzhj 4171 5 - - HYPH cord-005646-xhx9pzhj 4171 6 G6ran G6ran NNP cord-005646-xhx9pzhj 4171 7 Friberg Friberg NNP cord-005646-xhx9pzhj 4171 8 , , , cord-005646-xhx9pzhj 4171 9 G6sta G6sta NNP cord-005646-xhx9pzhj 4171 10 Mellgren Mellgren NNP cord-005646-xhx9pzhj 4171 11 , , , cord-005646-xhx9pzhj 4171 12 Hans Hans NNP cord-005646-xhx9pzhj 4171 13 Wadenvik Wadenvik NNP cord-005646-xhx9pzhj 4171 14 . . . cord-005646-xhx9pzhj 4172 1 G6teborg G6teborg NNP cord-005646-xhx9pzhj 4172 2 , , , cord-005646-xhx9pzhj 4172 3 Sweden Sweden NNP cord-005646-xhx9pzhj 4172 4 . . . cord-005646-xhx9pzhj 4173 1 Bleeding bleed VBG cord-005646-xhx9pzhj 4173 2 complications complication NNS cord-005646-xhx9pzhj 4173 3 in in IN cord-005646-xhx9pzhj 4173 4 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 4173 5 circulation circulation NN cord-005646-xhx9pzhj 4173 6 is be VBZ cord-005646-xhx9pzhj 4173 7 partly partly RB cord-005646-xhx9pzhj 4173 8 due due JJ cord-005646-xhx9pzhj 4173 9 to to IN cord-005646-xhx9pzhj 4173 10 perfusion perfusion NN cord-005646-xhx9pzhj 4173 11 - - HYPH cord-005646-xhx9pzhj 4173 12 induced induce VBN cord-005646-xhx9pzhj 4173 13 platelet platelet NN cord-005646-xhx9pzhj 4173 14 dysfunction dysfunction NN cord-005646-xhx9pzhj 4173 15 . . . cord-005646-xhx9pzhj 4174 1 The the DT cord-005646-xhx9pzhj 4174 2 aim aim NN cord-005646-xhx9pzhj 4174 3 of of IN cord-005646-xhx9pzhj 4174 4 this this DT cord-005646-xhx9pzhj 4174 5 study study NN cord-005646-xhx9pzhj 4174 6 was be VBD cord-005646-xhx9pzhj 4174 7 to to TO cord-005646-xhx9pzhj 4174 8 evaluate evaluate VB cord-005646-xhx9pzhj 4174 9 an an DT cord-005646-xhx9pzhj 4174 10 in in FW cord-005646-xhx9pzhj 4174 11 vitro vitro FW cord-005646-xhx9pzhj 4174 12 model model NN cord-005646-xhx9pzhj 4174 13 for for IN cord-005646-xhx9pzhj 4174 14 investigation investigation NN cord-005646-xhx9pzhj 4174 15 of of IN cord-005646-xhx9pzhj 4174 16 platelet platelet NN cord-005646-xhx9pzhj 4174 17 function function NN cord-005646-xhx9pzhj 4174 18 parameters parameter NNS cord-005646-xhx9pzhj 4174 19 in in IN cord-005646-xhx9pzhj 4174 20 an an DT cord-005646-xhx9pzhj 4174 21 extracorporeat extracorporeat JJ cord-005646-xhx9pzhj 4174 22 system system NN cord-005646-xhx9pzhj 4174 23 . . . cord-005646-xhx9pzhj 4175 1 Study study NN cord-005646-xhx9pzhj 4175 2 : : : cord-005646-xhx9pzhj 4176 1 Two two CD cord-005646-xhx9pzhj 4176 2 complete complete JJ cord-005646-xhx9pzhj 4176 3 extracorporeal extracorporeal JJ cord-005646-xhx9pzhj 4176 4 life life NN cord-005646-xhx9pzhj 4176 5 support support NN cord-005646-xhx9pzhj 4176 6 systems system NNS cord-005646-xhx9pzhj 4176 7 were be VBD cord-005646-xhx9pzhj 4176 8 perfused perfuse VBN cord-005646-xhx9pzhj 4176 9 with with IN cord-005646-xhx9pzhj 4176 10 fresh fresh JJ cord-005646-xhx9pzhj 4176 11 heparinized heparinized JJ cord-005646-xhx9pzhj 4176 12 human human JJ cord-005646-xhx9pzhj 4176 13 blood blood NN cord-005646-xhx9pzhj 4176 14 for for IN cord-005646-xhx9pzhj 4176 15 24 24 CD cord-005646-xhx9pzhj 4176 16 hours hour NNS cord-005646-xhx9pzhj 4176 17 . . . cord-005646-xhx9pzhj 4177 1 PIatetet piatetet NN cord-005646-xhx9pzhj 4177 2 membrane membrane NN cord-005646-xhx9pzhj 4177 3 glycoprotein glycoprotein NN cord-005646-xhx9pzhj 4177 4 changes change NNS cord-005646-xhx9pzhj 4177 5 , , , cord-005646-xhx9pzhj 4177 6 platelet platelet NN cord-005646-xhx9pzhj 4177 7 granule granule NN cord-005646-xhx9pzhj 4177 8 release release NN cord-005646-xhx9pzhj 4177 9 and and CC cord-005646-xhx9pzhj 4177 10 platelet platelet NN cord-005646-xhx9pzhj 4177 11 count count NN cord-005646-xhx9pzhj 4177 12 were be VBD cord-005646-xhx9pzhj 4177 13 followed follow VBN cord-005646-xhx9pzhj 4177 14 . . . cord-005646-xhx9pzhj 4178 1 Eight eight CD cord-005646-xhx9pzhj 4178 2 paired pair VBN cord-005646-xhx9pzhj 4178 3 experiments experiment NNS cord-005646-xhx9pzhj 4178 4 were be VBD cord-005646-xhx9pzhj 4178 5 performed perform VBN cord-005646-xhx9pzhj 4178 6 . . . cord-005646-xhx9pzhj 4179 1 One one CD cord-005646-xhx9pzhj 4179 2 of of IN cord-005646-xhx9pzhj 4179 3 the the DT cord-005646-xhx9pzhj 4179 4 circuits circuit NNS cord-005646-xhx9pzhj 4179 5 was be VBD cord-005646-xhx9pzhj 4179 6 perfused perfuse VBN cord-005646-xhx9pzhj 4179 7 by by IN cord-005646-xhx9pzhj 4179 8 a a DT cord-005646-xhx9pzhj 4179 9 roller roller NN cord-005646-xhx9pzhj 4179 10 pump pump NN cord-005646-xhx9pzhj 4179 11 ( ( -LRB- cord-005646-xhx9pzhj 4179 12 Polystan Polystan NNP cord-005646-xhx9pzhj 4179 13 ) ) -RRB- cord-005646-xhx9pzhj 4179 14 and and CC cord-005646-xhx9pzhj 4179 15 the the DT cord-005646-xhx9pzhj 4179 16 other other JJ cord-005646-xhx9pzhj 4179 17 by by IN cord-005646-xhx9pzhj 4179 18 a a DT cord-005646-xhx9pzhj 4179 19 centrifugal centrifugal JJ cord-005646-xhx9pzhj 4179 20 pump pump NN cord-005646-xhx9pzhj 4179 21 ( ( -LRB- cord-005646-xhx9pzhj 4179 22 Biomecicus Biomecicus NNP cord-005646-xhx9pzhj 4179 23 ) ) -RRB- cord-005646-xhx9pzhj 4179 24 , , , cord-005646-xhx9pzhj 4179 25 other other JJ cord-005646-xhx9pzhj 4179 26 components component NNS cord-005646-xhx9pzhj 4179 27 were be VBD cord-005646-xhx9pzhj 4179 28 identical identical JJ cord-005646-xhx9pzhj 4179 29 . . . cord-005646-xhx9pzhj 4180 1 Results result NNS cord-005646-xhx9pzhj 4180 2 : : : cord-005646-xhx9pzhj 4181 1 A a DT cord-005646-xhx9pzhj 4181 2 continuous continuous JJ cord-005646-xhx9pzhj 4181 3 increase increase NN cord-005646-xhx9pzhj 4181 4 in in IN cord-005646-xhx9pzhj 4181 5 glycoprotein glycoprotein NN cord-005646-xhx9pzhj 4181 6 ( ( -LRB- cord-005646-xhx9pzhj 4181 7 GP gp NN cord-005646-xhx9pzhj 4181 8 ) ) -RRB- cord-005646-xhx9pzhj 4182 1 Ib Ib NNP cord-005646-xhx9pzhj 4182 2 - - HYPH cord-005646-xhx9pzhj 4182 3 negative negative JJ cord-005646-xhx9pzhj 4182 4 platelets platelet NNS cord-005646-xhx9pzhj 4182 5 was be VBD cord-005646-xhx9pzhj 4182 6 seen see VBN cord-005646-xhx9pzhj 4182 7 in in IN cord-005646-xhx9pzhj 4182 8 both both DT cord-005646-xhx9pzhj 4182 9 circuits circuit NNS cord-005646-xhx9pzhj 4182 10 . . . cord-005646-xhx9pzhj 4183 1 A a DT cord-005646-xhx9pzhj 4183 2 marked marked JJ cord-005646-xhx9pzhj 4183 3 increase increase NN cord-005646-xhx9pzhj 4183 4 of of IN cord-005646-xhx9pzhj 4183 5 plasma plasma NN cord-005646-xhx9pzhj 4183 6 beta beta NN cord-005646-xhx9pzhj 4183 7 - - HYPH cord-005646-xhx9pzhj 4183 8 thromboglobulin thromboglobulin NN cord-005646-xhx9pzhj 4183 9 concentration concentration NN cord-005646-xhx9pzhj 4183 10 and and CC cord-005646-xhx9pzhj 4183 11 a a DT cord-005646-xhx9pzhj 4183 12 decrease decrease NN cord-005646-xhx9pzhj 4183 13 of of IN cord-005646-xhx9pzhj 4183 14 the the DT cord-005646-xhx9pzhj 4183 15 intracellular intracellular JJ cord-005646-xhx9pzhj 4183 16 pool pool NN cord-005646-xhx9pzhj 4183 17 of of IN cord-005646-xhx9pzhj 4183 18 serotonin serotonin NN cord-005646-xhx9pzhj 4183 19 was be VBD cord-005646-xhx9pzhj 4183 20 observed observe VBN cord-005646-xhx9pzhj 4183 21 , , , cord-005646-xhx9pzhj 4183 22 indicating indicate VBG cord-005646-xhx9pzhj 4183 23 a a DT cord-005646-xhx9pzhj 4183 24 marked marked JJ cord-005646-xhx9pzhj 4183 25 release release NN cord-005646-xhx9pzhj 4183 26 of of IN cord-005646-xhx9pzhj 4183 27 alpha alpha NN cord-005646-xhx9pzhj 4183 28 as as RB cord-005646-xhx9pzhj 4183 29 well well RB cord-005646-xhx9pzhj 4183 30 as as IN cord-005646-xhx9pzhj 4183 31 of of IN cord-005646-xhx9pzhj 4183 32 dense dense JJ cord-005646-xhx9pzhj 4183 33 granules granule NNS cord-005646-xhx9pzhj 4183 34 . . . cord-005646-xhx9pzhj 4184 1 The the DT cord-005646-xhx9pzhj 4184 2 plasma plasma NN cord-005646-xhx9pzhj 4184 3 concentration concentration NN cord-005646-xhx9pzhj 4184 4 of of IN cord-005646-xhx9pzhj 4184 5 glycocalioin glycocalioin NNP cord-005646-xhx9pzhj 4184 6 increased increase VBD cord-005646-xhx9pzhj 4184 7 in in IN cord-005646-xhx9pzhj 4184 8 parallel parallel NN cord-005646-xhx9pzhj 4184 9 with with IN cord-005646-xhx9pzhj 4184 10 a a DT cord-005646-xhx9pzhj 4184 11 reduced reduce VBN cord-005646-xhx9pzhj 4184 12 platelet platelet NN cord-005646-xhx9pzhj 4184 13 surface surface NN cord-005646-xhx9pzhj 4184 14 expression expression NN cord-005646-xhx9pzhj 4184 15 of of IN cord-005646-xhx9pzhj 4184 16 GPIb GPIb NNS cord-005646-xhx9pzhj 4184 17 , , , cord-005646-xhx9pzhj 4184 18 suggesting suggest VBG cord-005646-xhx9pzhj 4184 19 that that IN cord-005646-xhx9pzhj 4184 20 the the DT cord-005646-xhx9pzhj 4184 21 loss loss NN cord-005646-xhx9pzhj 4184 22 of of IN cord-005646-xhx9pzhj 4184 23 GPIb GPIb NNS cord-005646-xhx9pzhj 4184 24 is be VBZ cord-005646-xhx9pzhj 4184 25 caused cause VBN cord-005646-xhx9pzhj 4184 26 by by IN cord-005646-xhx9pzhj 4184 27 proteolysis proteolysis NN cord-005646-xhx9pzhj 4184 28 rather rather RB cord-005646-xhx9pzhj 4184 29 than than IN cord-005646-xhx9pzhj 4184 30 by by IN cord-005646-xhx9pzhj 4184 31 a a DT cord-005646-xhx9pzhj 4184 32 downregulation downregulation NN cord-005646-xhx9pzhj 4184 33 of of IN cord-005646-xhx9pzhj 4184 34 this this DT cord-005646-xhx9pzhj 4184 35 receptor receptor NN cord-005646-xhx9pzhj 4184 36 protein protein NN cord-005646-xhx9pzhj 4184 37 . . . cord-005646-xhx9pzhj 4185 1 Conclusion conclusion NN cord-005646-xhx9pzhj 4185 2 : : : cord-005646-xhx9pzhj 4185 3 24 24 CD cord-005646-xhx9pzhj 4185 4 hours hour NNS cord-005646-xhx9pzhj 4185 5 of of IN cord-005646-xhx9pzhj 4185 6 ECLS ECLS NNP cord-005646-xhx9pzhj 4185 7 perfusion perfusion NN cord-005646-xhx9pzhj 4185 8 induces induce VBZ cord-005646-xhx9pzhj 4185 9 pronounced pronounce VBN cord-005646-xhx9pzhj 4185 10 platelet platelet NN cord-005646-xhx9pzhj 4185 11 degranutation degranutation NN cord-005646-xhx9pzhj 4185 12 and and CC cord-005646-xhx9pzhj 4185 13 causes cause VBZ cord-005646-xhx9pzhj 4185 14 changes change NNS cord-005646-xhx9pzhj 4185 15 of of IN cord-005646-xhx9pzhj 4185 16 important important JJ cord-005646-xhx9pzhj 4185 17 membrane membrane NN cord-005646-xhx9pzhj 4185 18 receptors receptor NNS cord-005646-xhx9pzhj 4185 19 . . . cord-005646-xhx9pzhj 4186 1 This this DT cord-005646-xhx9pzhj 4186 2 is be VBZ cord-005646-xhx9pzhj 4186 3 in in IN cord-005646-xhx9pzhj 4186 4 accordance accordance NN cord-005646-xhx9pzhj 4186 5 with with IN cord-005646-xhx9pzhj 4186 6 clinical clinical JJ cord-005646-xhx9pzhj 4186 7 studies study NNS cord-005646-xhx9pzhj 4186 8 , , , cord-005646-xhx9pzhj 4186 9 suggesting suggest VBG cord-005646-xhx9pzhj 4186 10 that that IN cord-005646-xhx9pzhj 4186 11 our -PRON- PRP$ cord-005646-xhx9pzhj 4186 12 in in FW cord-005646-xhx9pzhj 4186 13 vitro vitro FW cord-005646-xhx9pzhj 4186 14 model model NN cord-005646-xhx9pzhj 4186 15 does do VBZ cord-005646-xhx9pzhj 4186 16 mirror mirror VB cord-005646-xhx9pzhj 4186 17 the the DT cord-005646-xhx9pzhj 4186 18 platelet platelet NN cord-005646-xhx9pzhj 4186 19 exhaustion exhaustion NN cord-005646-xhx9pzhj 4186 20 observed observe VBN cord-005646-xhx9pzhj 4186 21 in in IN cord-005646-xhx9pzhj 4186 22 a a DT cord-005646-xhx9pzhj 4186 23 clinical clinical JJ cord-005646-xhx9pzhj 4186 24 reality reality NN cord-005646-xhx9pzhj 4186 25 . . . cord-005646-xhx9pzhj 4187 1 No no DT cord-005646-xhx9pzhj 4187 2 significant significant JJ cord-005646-xhx9pzhj 4187 3 difference difference NN cord-005646-xhx9pzhj 4187 4 was be VBD cord-005646-xhx9pzhj 4187 5 observed observe VBN cord-005646-xhx9pzhj 4187 6 between between IN cord-005646-xhx9pzhj 4187 7 the the DT cord-005646-xhx9pzhj 4187 8 two two CD cord-005646-xhx9pzhj 4187 9 pumps pump NNS cord-005646-xhx9pzhj 4187 10 . . . cord-005646-xhx9pzhj 4188 1 The the DT cord-005646-xhx9pzhj 4188 2 purpose purpose NN cord-005646-xhx9pzhj 4188 3 of of IN cord-005646-xhx9pzhj 4188 4 this this DT cord-005646-xhx9pzhj 4188 5 study study NN cord-005646-xhx9pzhj 4188 6 was be VBD cord-005646-xhx9pzhj 4188 7 to to TO cord-005646-xhx9pzhj 4188 8 examine examine VB cord-005646-xhx9pzhj 4188 9 signs sign NNS cord-005646-xhx9pzhj 4188 10 of of IN cord-005646-xhx9pzhj 4188 11 distress distress NN cord-005646-xhx9pzhj 4188 12 exhibited exhibit VBN cord-005646-xhx9pzhj 4188 13 by by IN cord-005646-xhx9pzhj 4188 14 several several JJ cord-005646-xhx9pzhj 4188 15 patients patient NNS cord-005646-xhx9pzhj 4188 16 following follow VBG cord-005646-xhx9pzhj 4188 17 the the DT cord-005646-xhx9pzhj 4188 18 discontinuation discontinuation NN cord-005646-xhx9pzhj 4188 19 of of IN cord-005646-xhx9pzhj 4188 20 opioids opioid NNS cord-005646-xhx9pzhj 4188 21 and and CC cord-005646-xhx9pzhj 4188 22 benzodiazepines benzodiazepine NNS cord-005646-xhx9pzhj 4188 23 ( ( -LRB- cord-005646-xhx9pzhj 4188 24 O o UH cord-005646-xhx9pzhj 4188 25 & & CC cord-005646-xhx9pzhj 4188 26 B B NNP cord-005646-xhx9pzhj 4188 27 ) ) -RRB- cord-005646-xhx9pzhj 4188 28 in in IN cord-005646-xhx9pzhj 4188 29 a a DT cord-005646-xhx9pzhj 4188 30 7-bed 7-bed JJ cord-005646-xhx9pzhj 4188 31 pediatric pediatric JJ cord-005646-xhx9pzhj 4188 32 intensive intensive JJ cord-005646-xhx9pzhj 4188 33 care care NN cord-005646-xhx9pzhj 4188 34 unit unit NN cord-005646-xhx9pzhj 4188 35 . . . cord-005646-xhx9pzhj 4189 1 The the DT cord-005646-xhx9pzhj 4189 2 authors author NNS cord-005646-xhx9pzhj 4189 3 compiled compile VBD cord-005646-xhx9pzhj 4189 4 a a DT cord-005646-xhx9pzhj 4189 5 list list NN cord-005646-xhx9pzhj 4189 6 of of IN cord-005646-xhx9pzhj 4189 7 all all DT cord-005646-xhx9pzhj 4189 8 cases case NNS cord-005646-xhx9pzhj 4189 9 of of IN cord-005646-xhx9pzhj 4189 10 possible possible JJ cord-005646-xhx9pzhj 4189 11 withdrawal withdrawal NN cord-005646-xhx9pzhj 4189 12 reactions reaction NNS cord-005646-xhx9pzhj 4189 13 reported report VBN cord-005646-xhx9pzhj 4189 14 by by IN cord-005646-xhx9pzhj 4189 15 nurses nurse NNS cord-005646-xhx9pzhj 4189 16 in in IN cord-005646-xhx9pzhj 4189 17 the the DT cord-005646-xhx9pzhj 4189 18 study study NN cord-005646-xhx9pzhj 4189 19 setting set VBG cord-005646-xhx9pzhj 4189 20 over over RP cord-005646-xhx9pzhj 4189 21 a a DT cord-005646-xhx9pzhj 4189 22 one one CD cord-005646-xhx9pzhj 4189 23 - - HYPH cord-005646-xhx9pzhj 4189 24 year year NN cord-005646-xhx9pzhj 4189 25 period period NN cord-005646-xhx9pzhj 4189 26 . . . cord-005646-xhx9pzhj 4190 1 Five five CD cord-005646-xhx9pzhj 4190 2 cases case NNS cord-005646-xhx9pzhj 4190 3 were be VBD cord-005646-xhx9pzhj 4190 4 selected select VBN cord-005646-xhx9pzhj 4190 5 for for IN cord-005646-xhx9pzhj 4190 6 study study NN cord-005646-xhx9pzhj 4190 7 in in IN cord-005646-xhx9pzhj 4190 8 terms term NNS cord-005646-xhx9pzhj 4190 9 of of IN cord-005646-xhx9pzhj 4190 10 their -PRON- PRP$ cord-005646-xhx9pzhj 4190 11 wide wide JJ cord-005646-xhx9pzhj 4190 12 diversity diversity NN cord-005646-xhx9pzhj 4190 13 of of IN cord-005646-xhx9pzhj 4190 14 relevant relevant JJ cord-005646-xhx9pzhj 4190 15 circumstances circumstance NNS cord-005646-xhx9pzhj 4190 16 . . . cord-005646-xhx9pzhj 4191 1 The the DT cord-005646-xhx9pzhj 4191 2 5 5 CD cord-005646-xhx9pzhj 4191 3 cases case NNS cord-005646-xhx9pzhj 4191 4 were be VBD cord-005646-xhx9pzhj 4191 5 examined examine VBN cord-005646-xhx9pzhj 4191 6 through through IN cord-005646-xhx9pzhj 4191 7 a a DT cord-005646-xhx9pzhj 4191 8 retrospective retrospective JJ cord-005646-xhx9pzhj 4191 9 chart chart NN cord-005646-xhx9pzhj 4191 10 review review NN cord-005646-xhx9pzhj 4191 11 . . . cord-005646-xhx9pzhj 4192 1 Data datum NNS cord-005646-xhx9pzhj 4192 2 pertaining pertain VBG cord-005646-xhx9pzhj 4192 3 to to IN cord-005646-xhx9pzhj 4192 4 analgesic analgesic JJ cord-005646-xhx9pzhj 4192 5 and and CC cord-005646-xhx9pzhj 4192 6 sedative sedative JJ cord-005646-xhx9pzhj 4192 7 administration administration NN cord-005646-xhx9pzhj 4192 8 , , , cord-005646-xhx9pzhj 4192 9 along along IN cord-005646-xhx9pzhj 4192 10 with with IN cord-005646-xhx9pzhj 4192 11 nurses nurse NNS cord-005646-xhx9pzhj 4192 12 ' ' POS cord-005646-xhx9pzhj 4192 13 reports report NNS cord-005646-xhx9pzhj 4192 14 of of IN cord-005646-xhx9pzhj 4192 15 behavioral behavioral JJ cord-005646-xhx9pzhj 4192 16 distress distress NN cord-005646-xhx9pzhj 4192 17 , , , cord-005646-xhx9pzhj 4192 18 were be VBD cord-005646-xhx9pzhj 4192 19 transcribed transcribe VBN cord-005646-xhx9pzhj 4192 20 and and CC cord-005646-xhx9pzhj 4192 21 coded code VBN cord-005646-xhx9pzhj 4192 22 . . . cord-005646-xhx9pzhj 4193 1 A a DT cord-005646-xhx9pzhj 4193 2 remarkable remarkable JJ cord-005646-xhx9pzhj 4193 3 pattern pattern NN cord-005646-xhx9pzhj 4193 4 of of IN cord-005646-xhx9pzhj 4193 5 behavioral behavioral JJ cord-005646-xhx9pzhj 4193 6 distress distress NN cord-005646-xhx9pzhj 4193 7 was be VBD cord-005646-xhx9pzhj 4193 8 clearly clearly RB cord-005646-xhx9pzhj 4193 9 associated associate VBN cord-005646-xhx9pzhj 4193 10 with with IN cord-005646-xhx9pzhj 4193 11 discontinuation discontinuation NN cord-005646-xhx9pzhj 4193 12 of of IN cord-005646-xhx9pzhj 4193 13 O o NN cord-005646-xhx9pzhj 4193 14 & & CC cord-005646-xhx9pzhj 4193 15 B. B. NNP cord-005646-xhx9pzhj 4193 16 Cessation Cessation NNP cord-005646-xhx9pzhj 4193 17 of of IN cord-005646-xhx9pzhj 4193 18 benzodiazepines benzodiazepine NNS cord-005646-xhx9pzhj 4193 19 was be VBD cord-005646-xhx9pzhj 4193 20 associated associate VBN cord-005646-xhx9pzhj 4193 21 with with IN cord-005646-xhx9pzhj 4193 22 severe severe JJ cord-005646-xhx9pzhj 4193 23 distress distress NN cord-005646-xhx9pzhj 4193 24 . . . cord-005646-xhx9pzhj 4194 1 These these DT cord-005646-xhx9pzhj 4194 2 reactions reaction NNS cord-005646-xhx9pzhj 4194 3 were be VBD cord-005646-xhx9pzhj 4194 4 characterized characterize VBN cord-005646-xhx9pzhj 4194 5 by by IN cord-005646-xhx9pzhj 4194 6 various various JJ cord-005646-xhx9pzhj 4194 7 combinations combination NNS cord-005646-xhx9pzhj 4194 8 of of IN cord-005646-xhx9pzhj 4194 9 crying crying NN cord-005646-xhx9pzhj 4194 10 , , , cord-005646-xhx9pzhj 4194 11 irritability irritability NN cord-005646-xhx9pzhj 4194 12 , , , cord-005646-xhx9pzhj 4194 13 tremors tremor NNS cord-005646-xhx9pzhj 4194 14 , , , cord-005646-xhx9pzhj 4194 15 grimacing grimace VBG cord-005646-xhx9pzhj 4194 16 , , , cord-005646-xhx9pzhj 4194 17 gagging gag VBG cord-005646-xhx9pzhj 4194 18 , , , cord-005646-xhx9pzhj 4194 19 vomiting vomiting NN cord-005646-xhx9pzhj 4194 20 , , , cord-005646-xhx9pzhj 4194 21 or or CC cord-005646-xhx9pzhj 4194 22 feeding feeding NN cord-005646-xhx9pzhj 4194 23 problems problem NNS cord-005646-xhx9pzhj 4194 24 . . . cord-005646-xhx9pzhj 4195 1 Some some DT cord-005646-xhx9pzhj 4195 2 of of IN cord-005646-xhx9pzhj 4195 3 these these DT cord-005646-xhx9pzhj 4195 4 persisted persist VBD cord-005646-xhx9pzhj 4195 5 in in IN cord-005646-xhx9pzhj 4195 6 spite spite NN cord-005646-xhx9pzhj 4195 7 of of IN cord-005646-xhx9pzhj 4195 8 large large JJ cord-005646-xhx9pzhj 4195 9 amounts amount NNS cord-005646-xhx9pzhj 4195 10 of of IN cord-005646-xhx9pzhj 4195 11 bolus bolus NN cord-005646-xhx9pzhj 4195 12 drug drug NNP cord-005646-xhx9pzhj 4195 13 administration administration NNP cord-005646-xhx9pzhj 4195 14 . . . cord-005646-xhx9pzhj 4196 1 These these DT cord-005646-xhx9pzhj 4196 2 signs sign NNS cord-005646-xhx9pzhj 4196 3 were be VBD cord-005646-xhx9pzhj 4196 4 manifested manifest VBN cord-005646-xhx9pzhj 4196 5 for for IN cord-005646-xhx9pzhj 4196 6 2 2 CD cord-005646-xhx9pzhj 4196 7 to to TO cord-005646-xhx9pzhj 4196 8 9 9 CD cord-005646-xhx9pzhj 4196 9 days day NNS cord-005646-xhx9pzhj 4196 10 following follow VBG cord-005646-xhx9pzhj 4196 11 cessation cessation NN cord-005646-xhx9pzhj 4196 12 of of IN cord-005646-xhx9pzhj 4196 13 O o NN cord-005646-xhx9pzhj 4196 14 & & CC cord-005646-xhx9pzhj 4197 1 B. B. NNP cord-005646-xhx9pzhj 4197 2 These these DT cord-005646-xhx9pzhj 4197 3 findings finding NNS cord-005646-xhx9pzhj 4197 4 demonstrate demonstrate VBP cord-005646-xhx9pzhj 4197 5 that that IN cord-005646-xhx9pzhj 4197 6 the the DT cord-005646-xhx9pzhj 4197 7 rapid rapid JJ cord-005646-xhx9pzhj 4197 8 weaning weaning NN cord-005646-xhx9pzhj 4197 9 of of IN cord-005646-xhx9pzhj 4197 10 O o NN cord-005646-xhx9pzhj 4197 11 & & CC cord-005646-xhx9pzhj 4197 12 B B NNP cord-005646-xhx9pzhj 4197 13 infusions infusion NNS cord-005646-xhx9pzhj 4197 14 , , , cord-005646-xhx9pzhj 4197 15 sometimes sometimes RB cord-005646-xhx9pzhj 4197 16 following follow VBG cord-005646-xhx9pzhj 4197 17 short short JJ cord-005646-xhx9pzhj 4197 18 - - HYPH cord-005646-xhx9pzhj 4197 19 term term NN cord-005646-xhx9pzhj 4197 20 therapy therapy NN cord-005646-xhx9pzhj 4197 21 , , , cord-005646-xhx9pzhj 4197 22 can can MD cord-005646-xhx9pzhj 4197 23 cause cause VB cord-005646-xhx9pzhj 4197 24 severe severe JJ cord-005646-xhx9pzhj 4197 25 withdrawal withdrawal NN cord-005646-xhx9pzhj 4197 26 reactions reaction NNS cord-005646-xhx9pzhj 4197 27 . . . cord-005646-xhx9pzhj 4198 1 The the DT cord-005646-xhx9pzhj 4198 2 particular particular JJ cord-005646-xhx9pzhj 4198 3 course course NN cord-005646-xhx9pzhj 4198 4 that that IN cord-005646-xhx9pzhj 4198 5 a a DT cord-005646-xhx9pzhj 4198 6 specific specific JJ cord-005646-xhx9pzhj 4198 7 patient patient NN cord-005646-xhx9pzhj 4198 8 will will MD cord-005646-xhx9pzhj 4198 9 follow follow VB cord-005646-xhx9pzhj 4198 10 will will MD cord-005646-xhx9pzhj 4198 11 likely likely RB cord-005646-xhx9pzhj 4198 12 be be VB cord-005646-xhx9pzhj 4198 13 modulated modulate VBN cord-005646-xhx9pzhj 4198 14 by by IN cord-005646-xhx9pzhj 4198 15 underlying underlie VBG cord-005646-xhx9pzhj 4198 16 manifestations manifestation NNS cord-005646-xhx9pzhj 4198 17 of of IN cord-005646-xhx9pzhj 4198 18 " " `` cord-005646-xhx9pzhj 4198 19 ICU ICU NNP cord-005646-xhx9pzhj 4198 20 psychosis psychosis NN cord-005646-xhx9pzhj 4198 21 " " '' cord-005646-xhx9pzhj 4198 22 and and CC cord-005646-xhx9pzhj 4198 23 unresolved unresolved JJ cord-005646-xhx9pzhj 4198 24 pain pain NN cord-005646-xhx9pzhj 4198 25 and and CC cord-005646-xhx9pzhj 4198 26 emotional emotional JJ cord-005646-xhx9pzhj 4198 27 distress distress NN cord-005646-xhx9pzhj 4198 28 . . . cord-005646-xhx9pzhj 4199 1 Hermana Hermana NNP cord-005646-xhx9pzhj 4199 2 Tezano8 Tezano8 NNP cord-005646-xhx9pzhj 4199 3 MT MT NNP cord-005646-xhx9pzhj 4199 4 , , , cord-005646-xhx9pzhj 4199 5 Pilaf Pilaf NNP cord-005646-xhx9pzhj 4199 6 Orive Orive NNP cord-005646-xhx9pzhj 4199 7 J J NNP cord-005646-xhx9pzhj 4199 8 , , , cord-005646-xhx9pzhj 4199 9 Latorre Latorre NNP cord-005646-xhx9pzhj 4199 10 Garcia Garcia NNP cord-005646-xhx9pzhj 4199 11 J J NNP cord-005646-xhx9pzhj 4199 12 , , , cord-005646-xhx9pzhj 4199 13 Lizarraga Lizarraga NNP cord-005646-xhx9pzhj 4199 14 Azparren Azparren NNP cord-005646-xhx9pzhj 4199 15 MA MA NNP cord-005646-xhx9pzhj 4199 16 , , , cord-005646-xhx9pzhj 4199 17 Lopez Lopez NNP cord-005646-xhx9pzhj 4199 18 Bayon Bayon NNP cord-005646-xhx9pzhj 4199 19 J J NNP cord-005646-xhx9pzhj 4199 20 UCIP UCIP NNP cord-005646-xhx9pzhj 4199 21 Hospital Hospital NNP cord-005646-xhx9pzhj 4199 22 de de NNP cord-005646-xhx9pzhj 4199 23 Cruces Cruces NNP cord-005646-xhx9pzhj 4199 24 . . . cord-005646-xhx9pzhj 4200 1 Bilbao Bilbao NNP cord-005646-xhx9pzhj 4200 2 . . . cord-005646-xhx9pzhj 4201 1 SPAIN SPAIN NNP cord-005646-xhx9pzhj 4201 2 A a DT cord-005646-xhx9pzhj 4201 3 female female JJ cord-005646-xhx9pzhj 4201 4 child child NN cord-005646-xhx9pzhj 4201 5 , , , cord-005646-xhx9pzhj 4201 6 one one CD cord-005646-xhx9pzhj 4201 7 year year NN cord-005646-xhx9pzhj 4201 8 old old JJ cord-005646-xhx9pzhj 4201 9 , , , cord-005646-xhx9pzhj 4201 10 was be VBD cord-005646-xhx9pzhj 4201 11 referred refer VBN cord-005646-xhx9pzhj 4201 12 to to IN cord-005646-xhx9pzhj 4201 13 our -PRON- PRP$ cord-005646-xhx9pzhj 4201 14 Unit Unit NNP cord-005646-xhx9pzhj 4201 15 from from IN cord-005646-xhx9pzhj 4201 16 another another DT cord-005646-xhx9pzhj 4201 17 Hospital Hospital NNP cord-005646-xhx9pzhj 4201 18 because because IN cord-005646-xhx9pzhj 4201 19 she -PRON- PRP cord-005646-xhx9pzhj 4201 20 had have VBD cord-005646-xhx9pzhj 4201 21 ischemic ischemic JJ cord-005646-xhx9pzhj 4201 22 syntomsJn syntomsjn CD cord-005646-xhx9pzhj 4202 1 her -PRON- PRP$ cord-005646-xhx9pzhj 4202 2 right right JJ cord-005646-xhx9pzhj 4202 3 forearm forearm NN cord-005646-xhx9pzhj 4202 4 wich wich RB cord-005646-xhx9pzhj 4202 5 started start VBD cord-005646-xhx9pzhj 4202 6 three three CD cord-005646-xhx9pzhj 4202 7 days day NNS cord-005646-xhx9pzhj 4202 8 before before RB cord-005646-xhx9pzhj 4202 9 . . . cord-005646-xhx9pzhj 4203 1 She -PRON- PRP cord-005646-xhx9pzhj 4203 2 had have VBD cord-005646-xhx9pzhj 4203 3 ~i ~i NNP cord-005646-xhx9pzhj 4203 4 Downs Downs NNP cord-005646-xhx9pzhj 4203 5 syndrome syndrome NN cord-005646-xhx9pzhj 4203 6 and and CC cord-005646-xhx9pzhj 4203 7 Fallot Fallot NNP cord-005646-xhx9pzhj 4203 8 's 's POS cord-005646-xhx9pzhj 4203 9 tetralogy tetralogy NN cord-005646-xhx9pzhj 4203 10 with with IN cord-005646-xhx9pzhj 4203 11 a a DT cord-005646-xhx9pzhj 4203 12 systemic systemic JJ cord-005646-xhx9pzhj 4203 13 - - HYPH cord-005646-xhx9pzhj 4203 14 pulmonary pulmonary NN cord-005646-xhx9pzhj 4203 15 by by IN cord-005646-xhx9pzhj 4203 16 - - HYPH cord-005646-xhx9pzhj 4203 17 pass pass NN cord-005646-xhx9pzhj 4203 18 . . . cord-005646-xhx9pzhj 4204 1 Nine nine CD cord-005646-xhx9pzhj 4204 2 days day NNS cord-005646-xhx9pzhj 4204 3 before before IN cord-005646-xhx9pzhj 4204 4 the the DT cord-005646-xhx9pzhj 4204 5 admission admission NN cord-005646-xhx9pzhj 4204 6 in in IN cord-005646-xhx9pzhj 4204 7 our -PRON- PRP$ cord-005646-xhx9pzhj 4204 8 Hospital Hospital NNP cord-005646-xhx9pzhj 4204 9 she -PRON- PRP cord-005646-xhx9pzhj 4204 10 was be VBD cord-005646-xhx9pzhj 4204 11 undergone undergo VBN cord-005646-xhx9pzhj 4204 12 to to IN cord-005646-xhx9pzhj 4204 13 a a DT cord-005646-xhx9pzhj 4204 14 cardiac cardiac JJ cord-005646-xhx9pzhj 4204 15 catheterization catheterization NN cord-005646-xhx9pzhj 4204 16 by by IN cord-005646-xhx9pzhj 4205 1 arterial arterial JJ cord-005646-xhx9pzhj 4205 2 and and CC cord-005646-xhx9pzhj 4205 3 venous venous JJ cord-005646-xhx9pzhj 4205 4 femoral femoral JJ cord-005646-xhx9pzhj 4205 5 punctures puncture NNS cord-005646-xhx9pzhj 4205 6 with with IN cord-005646-xhx9pzhj 4205 7 no no DT cord-005646-xhx9pzhj 4205 8 incidences incidence NNS cord-005646-xhx9pzhj 4205 9 . . . cord-005646-xhx9pzhj 4206 1 On on IN cord-005646-xhx9pzhj 4206 2 the the DT cord-005646-xhx9pzhj 4206 3 admission admission NN cord-005646-xhx9pzhj 4206 4 to to IN cord-005646-xhx9pzhj 4206 5 the the DT cord-005646-xhx9pzhj 4206 6 PICU PICU NNP cord-005646-xhx9pzhj 4206 7 her -PRON- PRP$ cord-005646-xhx9pzhj 4206 8 forearm forearm NN cord-005646-xhx9pzhj 4206 9 was be VBD cord-005646-xhx9pzhj 4206 10 cold cold JJ cord-005646-xhx9pzhj 4206 11 and and CC cord-005646-xhx9pzhj 4206 12 pale pale JJ cord-005646-xhx9pzhj 4206 13 with with IN cord-005646-xhx9pzhj 4206 14 absence absence NN cord-005646-xhx9pzhj 4206 15 of of IN cord-005646-xhx9pzhj 4206 16 cubital cubital JJ cord-005646-xhx9pzhj 4206 17 and and CC cord-005646-xhx9pzhj 4206 18 radial radial JJ cord-005646-xhx9pzhj 4206 19 pulses pulse NNS cord-005646-xhx9pzhj 4206 20 and and CC cord-005646-xhx9pzhj 4206 21 slow slow JJ cord-005646-xhx9pzhj 4206 22 capilary capilary NNP cord-005646-xhx9pzhj 4206 23 filling filling NN cord-005646-xhx9pzhj 4206 24 . . . cord-005646-xhx9pzhj 4207 1 Treatment treatment NN cord-005646-xhx9pzhj 4207 2 with with IN cord-005646-xhx9pzhj 4207 3 Heparine Heparine NNP cord-005646-xhx9pzhj 4207 4 was be VBD cord-005646-xhx9pzhj 4207 5 started start VBN cord-005646-xhx9pzhj 4207 6 unsucessfully unsucessfully RB cord-005646-xhx9pzhj 4207 7 in in IN cord-005646-xhx9pzhj 4207 8 the the DT cord-005646-xhx9pzhj 4207 9 firsts first NNS cord-005646-xhx9pzhj 4207 10 24 24 CD cord-005646-xhx9pzhj 4207 11 hours hour NNS cord-005646-xhx9pzhj 4207 12 , , , cord-005646-xhx9pzhj 4207 13 so so RB cord-005646-xhx9pzhj 4207 14 uroquinase uroquinase NNP cord-005646-xhx9pzhj 4207 15 was be VBD cord-005646-xhx9pzhj 4207 16 added add VBN cord-005646-xhx9pzhj 4207 17 that that IN cord-005646-xhx9pzhj 4207 18 later later RB cord-005646-xhx9pzhj 4207 19 was be VBD cord-005646-xhx9pzhj 4207 20 changed change VBN cord-005646-xhx9pzhj 4207 21 to to IN cord-005646-xhx9pzhj 4207 22 rTPA rtpa JJ cord-005646-xhx9pzhj 4207 23 plus plus CC cord-005646-xhx9pzhj 4207 24 brachial brachial JJ cord-005646-xhx9pzhj 4207 25 plexus plexus NN cord-005646-xhx9pzhj 4207 26 blockade blockade NN cord-005646-xhx9pzhj 4207 27 . . . cord-005646-xhx9pzhj 4208 1 By by IN cord-005646-xhx9pzhj 4208 2 the the DT cord-005646-xhx9pzhj 4208 3 time time NN cord-005646-xhx9pzhj 4208 4 me -PRON- PRP cord-005646-xhx9pzhj 4208 5 arterial arterial JJ cord-005646-xhx9pzhj 4208 6 tlux tlux NN cord-005646-xhx9pzhj 4208 7 became become VBD cord-005646-xhx9pzhj 4208 8 more more RBR cord-005646-xhx9pzhj 4208 9 and and CC cord-005646-xhx9pzhj 4208 10 more more RBR cord-005646-xhx9pzhj 4208 11 evident evident JJ cord-005646-xhx9pzhj 4208 12 ( ( -LRB- cord-005646-xhx9pzhj 4208 13 Doppi~ doppi~ ADD cord-005646-xhx9pzhj 4208 14 ) ) -RRB- cord-005646-xhx9pzhj 4209 1 iL iL NNP cord-005646-xhx9pzhj 4209 2 bccuute bccuute NNP cord-005646-xhx9pzhj 4209 3 aiat aiat NNP cord-005646-xhx9pzhj 4209 4 ) ) -RRB- cord-005646-xhx9pzhj 4209 5 evident evident JJ cord-005646-xhx9pzhj 4209 6 a a DT cord-005646-xhx9pzhj 4209 7 regional regional JJ cord-005646-xhx9pzhj 4209 8 aedema aedema NNP cord-005646-xhx9pzhj 4209 9 witch witch NN cord-005646-xhx9pzhj 4209 10 made make VBD cord-005646-xhx9pzhj 4209 11 necessary necessary JJ cord-005646-xhx9pzhj 4209 12 a a DT cord-005646-xhx9pzhj 4209 13 fasciectomy fasciectomy NN cord-005646-xhx9pzhj 4209 14 & & CC cord-005646-xhx9pzhj 4209 15 the the DT cord-005646-xhx9pzhj 4209 16 wrist wrist NN cord-005646-xhx9pzhj 4209 17 . . . cord-005646-xhx9pzhj 4210 1 She -PRON- PRP cord-005646-xhx9pzhj 4210 2 also also RB cord-005646-xhx9pzhj 4210 3 developped developpe VBD cord-005646-xhx9pzhj 4210 4 necrotic necrotic JJ cord-005646-xhx9pzhj 4210 5 delimitted delimitted JJ cord-005646-xhx9pzhj 4210 6 areas area NNS cord-005646-xhx9pzhj 4210 7 that that WDT cord-005646-xhx9pzhj 4210 8 included include VBD cord-005646-xhx9pzhj 4210 9 her -PRON- PRP$ cord-005646-xhx9pzhj 4210 10 first first JJ cord-005646-xhx9pzhj 4210 11 and and CC cord-005646-xhx9pzhj 4210 12 fifth fifth JJ cord-005646-xhx9pzhj 4210 13 fingers finger NNS cord-005646-xhx9pzhj 4210 14 . . . cord-005646-xhx9pzhj 4211 1 She -PRON- PRP cord-005646-xhx9pzhj 4211 2 was be VBD cord-005646-xhx9pzhj 4211 3 discharged discharge VBN cord-005646-xhx9pzhj 4211 4 from from IN cord-005646-xhx9pzhj 4211 5 the the DT cord-005646-xhx9pzhj 4211 6 PICU PICU NNP cord-005646-xhx9pzhj 4211 7 after after IN cord-005646-xhx9pzhj 4211 8 13 13 CD cord-005646-xhx9pzhj 4211 9 days day NNS cord-005646-xhx9pzhj 4211 10 and and CC cord-005646-xhx9pzhj 4211 11 a a DT cord-005646-xhx9pzhj 4211 12 week week NN cord-005646-xhx9pzhj 4211 13 later later RB cord-005646-xhx9pzhj 4211 14 she -PRON- PRP cord-005646-xhx9pzhj 4211 15 went go VBD cord-005646-xhx9pzhj 4211 16 to to IN cord-005646-xhx9pzhj 4211 17 the the DT cord-005646-xhx9pzhj 4211 18 operating operating NN cord-005646-xhx9pzhj 4211 19 room room NN cord-005646-xhx9pzhj 4211 20 where where WRB cord-005646-xhx9pzhj 4211 21 an an DT cord-005646-xhx9pzhj 4211 22 amputation amputation NN cord-005646-xhx9pzhj 4211 23 of of IN cord-005646-xhx9pzhj 4211 24 the the DT cord-005646-xhx9pzhj 4211 25 distal distal JJ cord-005646-xhx9pzhj 4211 26 phalange phalange NN cord-005646-xhx9pzhj 4211 27 of of IN cord-005646-xhx9pzhj 4211 28 the the DT cord-005646-xhx9pzhj 4211 29 fifth fifth JJ cord-005646-xhx9pzhj 4211 30 finger finger NN cord-005646-xhx9pzhj 4211 31 was be VBD cord-005646-xhx9pzhj 4211 32 made make VBN cord-005646-xhx9pzhj 4211 33 . . . cord-005646-xhx9pzhj 4212 1 The the DT cord-005646-xhx9pzhj 4212 2 etiolgy etiolgy NNS cord-005646-xhx9pzhj 4212 3 of of IN cord-005646-xhx9pzhj 4212 4 this this DT cord-005646-xhx9pzhj 4212 5 ischemic ischemic JJ cord-005646-xhx9pzhj 4212 6 picture picture NN cord-005646-xhx9pzhj 4212 7 ca can MD cord-005646-xhx9pzhj 4212 8 n't not RB cord-005646-xhx9pzhj 4212 9 be be VB cord-005646-xhx9pzhj 4212 10 attributed attribute VBN cord-005646-xhx9pzhj 4212 11 to to IN cord-005646-xhx9pzhj 4212 12 the the DT cord-005646-xhx9pzhj 4212 13 catheterization catheterization NN cord-005646-xhx9pzhj 4212 14 itself -PRON- PRP cord-005646-xhx9pzhj 4212 15 , , , cord-005646-xhx9pzhj 4212 16 but but CC cord-005646-xhx9pzhj 4212 17 probably probably RB cord-005646-xhx9pzhj 4212 18 it -PRON- PRP cord-005646-xhx9pzhj 4212 19 should should MD cord-005646-xhx9pzhj 4212 20 be be VB cord-005646-xhx9pzhj 4212 21 due due JJ cord-005646-xhx9pzhj 4212 22 to to IN cord-005646-xhx9pzhj 4212 23 some some DT cord-005646-xhx9pzhj 4212 24 attempts attempt NNS cord-005646-xhx9pzhj 4212 25 in in IN cord-005646-xhx9pzhj 4212 26 arterial arterial JJ cord-005646-xhx9pzhj 4212 27 puncture puncture NN cord-005646-xhx9pzhj 4212 28 in in IN cord-005646-xhx9pzhj 4212 29 its -PRON- PRP$ cord-005646-xhx9pzhj 4212 30 course course NN cord-005646-xhx9pzhj 4212 31 , , , cord-005646-xhx9pzhj 4212 32 attempts attempt VBZ cord-005646-xhx9pzhj 4212 33 that that WDT cord-005646-xhx9pzhj 4212 34 could could MD cord-005646-xhx9pzhj 4212 35 be be VB cord-005646-xhx9pzhj 4212 36 guess gues VBN cord-005646-xhx9pzhj 4212 37 by by IN cord-005646-xhx9pzhj 4212 38 the the DT cord-005646-xhx9pzhj 4212 39 little little JJ cord-005646-xhx9pzhj 4212 40 marks mark NNS cord-005646-xhx9pzhj 4212 41 noticed notice VBN cord-005646-xhx9pzhj 4212 42 at at IN cord-005646-xhx9pzhj 4212 43 the the DT cord-005646-xhx9pzhj 4212 44 elbow elbow NN cord-005646-xhx9pzhj 4212 45 flexure flexure NN cord-005646-xhx9pzhj 4212 46 when when WRB cord-005646-xhx9pzhj 4212 47 she -PRON- PRP cord-005646-xhx9pzhj 4212 48 was be VBD cord-005646-xhx9pzhj 4212 49 admitted admit VBN cord-005646-xhx9pzhj 4212 50 . . . cord-005646-xhx9pzhj 4213 1 LONG long JJ cord-005646-xhx9pzhj 4213 2 MAINTENANCE maintenance NN cord-005646-xhx9pzhj 4213 3 OF of IN cord-005646-xhx9pzhj 4213 4 CARDIOVASCULAR cardiovascular NN cord-005646-xhx9pzhj 4213 5 FUNTION FUNTION NNP cord-005646-xhx9pzhj 4214 1 BY by IN cord-005646-xhx9pzhj 4214 2 ASSISTED assisted JJ cord-005646-xhx9pzhj 4214 3 VENTRICULAR ventricular NN cord-005646-xhx9pzhj 4214 4 DEVICE device NN cord-005646-xhx9pzhj 4214 5 WITH with IN cord-005646-xhx9pzhj 4214 6 MEMBRANE membrane NN cord-005646-xhx9pzhj 4214 7 OXIGENATOR OXIGENATOR NNP cord-005646-xhx9pzhj 4214 8 Hermana Hermana NNP cord-005646-xhx9pzhj 4214 9 Tezanos Tezanos NNP cord-005646-xhx9pzhj 4214 10 MT MT NNP cord-005646-xhx9pzhj 4214 11 , , , cord-005646-xhx9pzhj 4214 12 Pilar Pilar NNP cord-005646-xhx9pzhj 4214 13 Orive Orive NNP cord-005646-xhx9pzhj 4215 1 J. J. NNP cord-005646-xhx9pzhj 4215 2 Latorre Latorre NNP cord-005646-xhx9pzhj 4215 3 Garcia Garcia NNP cord-005646-xhx9pzhj 4215 4 J J NNP cord-005646-xhx9pzhj 4215 5 , , , cord-005646-xhx9pzhj 4215 6 Lizarraga Lizarraga NNP cord-005646-xhx9pzhj 4215 7 Azparren Azparren NNP cord-005646-xhx9pzhj 4215 8 MA MA NNP cord-005646-xhx9pzhj 4215 9 Lopez Lopez NNP cord-005646-xhx9pzhj 4215 10 Bay6n Bay6n NNP cord-005646-xhx9pzhj 4215 11 J. J. NNP cord-005646-xhx9pzhj 4215 12 UCIP UCIP NNP cord-005646-xhx9pzhj 4215 13 . . . cord-005646-xhx9pzhj 4216 1 Hospital Hospital NNP cord-005646-xhx9pzhj 4216 2 de de NNP cord-005646-xhx9pzhj 4216 3 Cruces Cruces NNP cord-005646-xhx9pzhj 4216 4 . . . cord-005646-xhx9pzhj 4217 1 Bilbao Bilbao NNP cord-005646-xhx9pzhj 4217 2 . . . cord-005646-xhx9pzhj 4218 1 SPAIN SPAIN NNP cord-005646-xhx9pzhj 4219 1 A a DT cord-005646-xhx9pzhj 4219 2 little little JJ cord-005646-xhx9pzhj 4219 3 girl girl NN cord-005646-xhx9pzhj 4219 4 of of IN cord-005646-xhx9pzhj 4219 5 three three CD cord-005646-xhx9pzhj 4219 6 and and CC cord-005646-xhx9pzhj 4219 7 a a DT cord-005646-xhx9pzhj 4219 8 half half NN cord-005646-xhx9pzhj 4219 9 years year NNS cord-005646-xhx9pzhj 4219 10 came come VBD cord-005646-xhx9pzhj 4219 11 to to IN cord-005646-xhx9pzhj 4219 12 the the DT cord-005646-xhx9pzhj 4219 13 Intensive Intensive NNP cord-005646-xhx9pzhj 4219 14 Care Care NNP cord-005646-xhx9pzhj 4219 15 Unit Unit NNP cord-005646-xhx9pzhj 4219 16 from from IN cord-005646-xhx9pzhj 4219 17 the the DT cord-005646-xhx9pzhj 4219 18 operating operating NN cord-005646-xhx9pzhj 4219 19 room room NN cord-005646-xhx9pzhj 4219 20 . . . cord-005646-xhx9pzhj 4220 1 Affected affect VBN cord-005646-xhx9pzhj 4220 2 of of IN cord-005646-xhx9pzhj 4220 3 great great JJ cord-005646-xhx9pzhj 4220 4 vessels vessel NNS cord-005646-xhx9pzhj 4220 5 transposition transposition NN cord-005646-xhx9pzhj 4220 6 with with IN cord-005646-xhx9pzhj 4220 7 a a DT cord-005646-xhx9pzhj 4220 8 pulmona~ pulmona~ NNS cord-005646-xhx9pzhj 4220 9 ' ' POS cord-005646-xhx9pzhj 4220 10 banding banding NN cord-005646-xhx9pzhj 4220 11 corrected correct VBD cord-005646-xhx9pzhj 4220 12 vith vith JJ cord-005646-xhx9pzhj 4220 13 Rastelli Rastelli NNP cord-005646-xhx9pzhj 4220 14 technique technique NN cord-005646-xhx9pzhj 4220 15 , , , cord-005646-xhx9pzhj 4220 16 it -PRON- PRP cord-005646-xhx9pzhj 4220 17 became become VBD cord-005646-xhx9pzhj 4220 18 impossible impossible JJ cord-005646-xhx9pzhj 4220 19 to to TO cord-005646-xhx9pzhj 4220 20 discharge discharge VB cord-005646-xhx9pzhj 4220 21 her -PRON- PRP cord-005646-xhx9pzhj 4220 22 from from IN cord-005646-xhx9pzhj 4220 23 the the DT cord-005646-xhx9pzhj 4220 24 by by IN cord-005646-xhx9pzhj 4220 25 - - HYPH cord-005646-xhx9pzhj 4220 26 pass pass NN cord-005646-xhx9pzhj 4220 27 circulation circulation NN cord-005646-xhx9pzhj 4220 28 . . . cord-005646-xhx9pzhj 4221 1 It -PRON- PRP cord-005646-xhx9pzhj 4221 2 was be VBD cord-005646-xhx9pzhj 4221 3 assumed assume VBN cord-005646-xhx9pzhj 4221 4 that that IN cord-005646-xhx9pzhj 4221 5 this this DT cord-005646-xhx9pzhj 4221 6 factt factt NN cord-005646-xhx9pzhj 4221 7 was be VBD cord-005646-xhx9pzhj 4221 8 due due JJ cord-005646-xhx9pzhj 4221 9 to to IN cord-005646-xhx9pzhj 4221 10 a a DT cord-005646-xhx9pzhj 4221 11 transient transient JJ cord-005646-xhx9pzhj 4221 12 myocardial myocardial JJ cord-005646-xhx9pzhj 4221 13 disfunction disfunction NN cord-005646-xhx9pzhj 4221 14 dfter dfter NN cord-005646-xhx9pzhj 4221 15 the the DT cord-005646-xhx9pzhj 4221 16 surgeon surgeon NN cord-005646-xhx9pzhj 4222 1 x x LS cord-005646-xhx9pzhj 4222 2 ~ ~ NFP cord-005646-xhx9pzhj 4222 3 ent ent XX cord-005646-xhx9pzhj 4222 4 through through IN cord-005646-xhx9pzhj 4222 5 the the DT cord-005646-xhx9pzhj 4222 6 technique technique NN cord-005646-xhx9pzhj 4222 7 and and CC cord-005646-xhx9pzhj 4222 8 found find VBD cord-005646-xhx9pzhj 4222 9 no no DT cord-005646-xhx9pzhj 4222 10 wrong wrong JJ cord-005646-xhx9pzhj 4222 11 step step NN cord-005646-xhx9pzhj 4222 12 in in IN cord-005646-xhx9pzhj 4222 13 it -PRON- PRP cord-005646-xhx9pzhj 4222 14 . . . cord-005646-xhx9pzhj 4223 1 At at IN cord-005646-xhx9pzhj 4223 2 the the DT cord-005646-xhx9pzhj 4223 3 PICU PICU NNP cord-005646-xhx9pzhj 4223 4 admission admission NN cord-005646-xhx9pzhj 4223 5 she -PRON- PRP cord-005646-xhx9pzhj 4223 6 had have VBD cord-005646-xhx9pzhj 4223 7 an an DT cord-005646-xhx9pzhj 4223 8 ejection ejection NN cord-005646-xhx9pzhj 4223 9 fraction fraction NN cord-005646-xhx9pzhj 4224 1 belox~ belox~ NNP cord-005646-xhx9pzhj 4224 2 20 20 CD cord-005646-xhx9pzhj 4224 3 % % NN cord-005646-xhx9pzhj 4224 4 ( ( -LRB- cord-005646-xhx9pzhj 4224 5 Echncardiografy Echncardiografy NNP cord-005646-xhx9pzhj 4224 6 ) ) -RRB- cord-005646-xhx9pzhj 4224 7 , , , cord-005646-xhx9pzhj 4224 8 and and CC cord-005646-xhx9pzhj 4224 9 was be VBD cord-005646-xhx9pzhj 4224 10 manteined manteine VBN cord-005646-xhx9pzhj 4224 11 on on IN cord-005646-xhx9pzhj 4224 12 veutricular veutricular JJ cord-005646-xhx9pzhj 4224 13 assistance assistance NN cord-005646-xhx9pzhj 4224 14 with with IN cord-005646-xhx9pzhj 4224 15 a a DT cord-005646-xhx9pzhj 4224 16 circuit circuit NN cord-005646-xhx9pzhj 4224 17 consisting consist VBG cord-005646-xhx9pzhj 4224 18 ofa ofa NNP cord-005646-xhx9pzhj 4224 19 plate plate NN cord-005646-xhx9pzhj 4224 20 's 's POS cord-005646-xhx9pzhj 4224 21 membrane membrane NN cord-005646-xhx9pzhj 4224 22 oxigenator oxigenator NN cord-005646-xhx9pzhj 4224 23 , , , cord-005646-xhx9pzhj 4224 24 a a DT cord-005646-xhx9pzhj 4224 25 Bio Bio NNP cord-005646-xhx9pzhj 4224 26 - - HYPH cord-005646-xhx9pzhj 4224 27 Medicus Medicus NNP cord-005646-xhx9pzhj 4224 28 pump pump NN cord-005646-xhx9pzhj 4224 29 and and CC cord-005646-xhx9pzhj 4224 30 PVC pvc NN cord-005646-xhx9pzhj 4224 31 rubber rubber NN cord-005646-xhx9pzhj 4224 32 tubes tube NNS cord-005646-xhx9pzhj 4224 33 , , , cord-005646-xhx9pzhj 4224 34 with with IN cord-005646-xhx9pzhj 4224 35 monitoring monitoring NN cord-005646-xhx9pzhj 4224 36 of of IN cord-005646-xhx9pzhj 4224 37 pulmonary pulmonary NNP cord-005646-xhx9pzhj 4224 38 ' ' '' cord-005646-xhx9pzhj 4224 39 , , , cord-005646-xhx9pzhj 4224 40 right right UH cord-005646-xhx9pzhj 4224 41 and and CC cord-005646-xhx9pzhj 4224 42 left left JJ cord-005646-xhx9pzhj 4224 43 atrial atrial JJ cord-005646-xhx9pzhj 4224 44 pressures pressure NNS cord-005646-xhx9pzhj 4224 45 . . . cord-005646-xhx9pzhj 4225 1 Initially initially RB cord-005646-xhx9pzhj 4225 2 she -PRON- PRP cord-005646-xhx9pzhj 4225 3 needed need VBD cord-005646-xhx9pzhj 4225 4 a a DT cord-005646-xhx9pzhj 4225 5 ventncular ventncular JJ cord-005646-xhx9pzhj 4225 6 support support NN cord-005646-xhx9pzhj 4225 7 of of IN cord-005646-xhx9pzhj 4225 8 1.2 1.2 CD cord-005646-xhx9pzhj 4225 9 L l NN cord-005646-xhx9pzhj 4225 10 / / SYM cord-005646-xhx9pzhj 4225 11 min min NN cord-005646-xhx9pzhj 4225 12 with with IN cord-005646-xhx9pzhj 4225 13 Dopamine dopamine NN cord-005646-xhx9pzhj 4225 14 . . . cord-005646-xhx9pzhj 4226 1 Dobutamine Dobutamine NNP cord-005646-xhx9pzhj 4226 2 and and CC cord-005646-xhx9pzhj 4226 3 Adrenaline adrenaline NN cord-005646-xhx9pzhj 4226 4 ; ; : cord-005646-xhx9pzhj 4226 5 gradually gradually RB cord-005646-xhx9pzhj 4226 6 the the DT cord-005646-xhx9pzhj 4226 7 ejection ejection NN cord-005646-xhx9pzhj 4226 8 fraction fraction NN cord-005646-xhx9pzhj 4226 9 rose rise VBD cord-005646-xhx9pzhj 4226 10 to to IN cord-005646-xhx9pzhj 4226 11 60 60 CD cord-005646-xhx9pzhj 4226 12 % % NN cord-005646-xhx9pzhj 4226 13 alIowing aliowe VBG cord-005646-xhx9pzhj 4226 14 a a DT cord-005646-xhx9pzhj 4226 15 decrease decrease NN cord-005646-xhx9pzhj 4226 16 in in IN cord-005646-xhx9pzhj 4226 17 the the DT cord-005646-xhx9pzhj 4226 18 mechanical mechanical JJ cord-005646-xhx9pzhj 4226 19 and and CC cord-005646-xhx9pzhj 4226 20 inotropic inotropic NNP cord-005646-xhx9pzhj 4226 21 support support NN cord-005646-xhx9pzhj 4226 22 . . . cord-005646-xhx9pzhj 4227 1 The the DT cord-005646-xhx9pzhj 4227 2 organic organic JJ cord-005646-xhx9pzhj 4227 3 function function NN cord-005646-xhx9pzhj 4227 4 , , , cord-005646-xhx9pzhj 4227 5 .'.-as .'.-as . cord-005646-xhx9pzhj 4228 1 preserved preserve VBN cord-005646-xhx9pzhj 4228 2 but but CC cord-005646-xhx9pzhj 4228 3 X X NNP cord-005646-xhx9pzhj 4228 4 - - NN cord-005646-xhx9pzhj 4228 5 Ray Ray NNP cord-005646-xhx9pzhj 4228 6 of of IN cord-005646-xhx9pzhj 4228 7 the the DT cord-005646-xhx9pzhj 4228 8 thorax thorax NN cord-005646-xhx9pzhj 4228 9 showed show VBD cord-005646-xhx9pzhj 4228 10 images image NNS cord-005646-xhx9pzhj 4228 11 of of IN cord-005646-xhx9pzhj 4228 12 pulmonary pulmonary JJ cord-005646-xhx9pzhj 4228 13 aedema aedema NN cord-005646-xhx9pzhj 4228 14 with with IN cord-005646-xhx9pzhj 4228 15 an an DT cord-005646-xhx9pzhj 4228 16 increase increase NN cord-005646-xhx9pzhj 4228 17 in in IN cord-005646-xhx9pzhj 4228 18 the the DT cord-005646-xhx9pzhj 4228 19 02 02 CD cord-005646-xhx9pzhj 4228 20 needs need NNS cord-005646-xhx9pzhj 4228 21 until until IN cord-005646-xhx9pzhj 4228 22 a a DT cord-005646-xhx9pzhj 4228 23 Fi02 Fi02 NNP cord-005646-xhx9pzhj 4228 24 of of IN cord-005646-xhx9pzhj 4228 25 0.4 0.4 CD cord-005646-xhx9pzhj 4228 26 . . . cord-005646-xhx9pzhj 4229 1 Even even RB cord-005646-xhx9pzhj 4229 2 though though IN cord-005646-xhx9pzhj 4229 3 she -PRON- PRP cord-005646-xhx9pzhj 4229 4 was be VBD cord-005646-xhx9pzhj 4229 5 placed place VBN cord-005646-xhx9pzhj 4229 6 in in IN cord-005646-xhx9pzhj 4229 7 a a DT cord-005646-xhx9pzhj 4229 8 transplant transplant NN cord-005646-xhx9pzhj 4229 9 program program NN cord-005646-xhx9pzhj 4229 10 , , , cord-005646-xhx9pzhj 4229 11 she -PRON- PRP cord-005646-xhx9pzhj 4229 12 was be VBD cord-005646-xhx9pzhj 4229 13 remouved remouve VBN cord-005646-xhx9pzhj 4229 14 when when WRB cord-005646-xhx9pzhj 4229 15 the the DT cord-005646-xhx9pzhj 4229 16 ejection ejection NN cord-005646-xhx9pzhj 4229 17 fraction fraction NN cord-005646-xhx9pzhj 4229 18 rose rise VBD cord-005646-xhx9pzhj 4229 19 to to IN cord-005646-xhx9pzhj 4229 20 50 50 CD cord-005646-xhx9pzhj 4229 21 % % NN cord-005646-xhx9pzhj 4229 22 on on IN cord-005646-xhx9pzhj 4229 23 the the DT cord-005646-xhx9pzhj 4229 24 1 1 CD cord-005646-xhx9pzhj 4229 25 lth lth NN cord-005646-xhx9pzhj 4229 26 da da NNP cord-005646-xhx9pzhj 4229 27 3 3 CD cord-005646-xhx9pzhj 4229 28 of of IN cord-005646-xhx9pzhj 4229 29 the the DT cord-005646-xhx9pzhj 4229 30 evolution evolution NN cord-005646-xhx9pzhj 4229 31 . . . cord-005646-xhx9pzhj 4230 1 There there EX cord-005646-xhx9pzhj 4230 2 were be VBD cord-005646-xhx9pzhj 4230 3 no no DT cord-005646-xhx9pzhj 4230 4 signs sign NNS cord-005646-xhx9pzhj 4230 5 of of IN cord-005646-xhx9pzhj 4230 6 infection infection NN cord-005646-xhx9pzhj 4230 7 ( ( -LRB- cord-005646-xhx9pzhj 4230 8 profilactic profilactic NN cord-005646-xhx9pzhj 4230 9 coverage coverage NN cord-005646-xhx9pzhj 4230 10 ) ) -RRB- cord-005646-xhx9pzhj 4230 11 . . . cord-005646-xhx9pzhj 4231 1 On on IN cord-005646-xhx9pzhj 4231 2 the the DT cord-005646-xhx9pzhj 4231 3 fifhteen fifhteen NN cord-005646-xhx9pzhj 4231 4 postsurgery postsurgery NNP cord-005646-xhx9pzhj 4231 5 day day NN cord-005646-xhx9pzhj 4231 6 . . . cord-005646-xhx9pzhj 4232 1 with with IN cord-005646-xhx9pzhj 4232 2 a a DT cord-005646-xhx9pzhj 4232 3 good good JJ cord-005646-xhx9pzhj 4232 4 cardiac cardiac JJ cord-005646-xhx9pzhj 4232 5 sound sound NN cord-005646-xhx9pzhj 4232 6 and and CC cord-005646-xhx9pzhj 4232 7 an an DT cord-005646-xhx9pzhj 4232 8 ejection ejection NN cord-005646-xhx9pzhj 4232 9 fraction fraction NN cord-005646-xhx9pzhj 4232 10 of of IN cord-005646-xhx9pzhj 4232 11 at at RB cord-005646-xhx9pzhj 4232 12 least least RBS cord-005646-xhx9pzhj 4232 13 60 60 CD cord-005646-xhx9pzhj 4232 14 % % NN cord-005646-xhx9pzhj 4232 15 . . . cord-005646-xhx9pzhj 4233 1 it -PRON- PRP cord-005646-xhx9pzhj 4233 2 was be VBD cord-005646-xhx9pzhj 4233 3 considered consider VBN cord-005646-xhx9pzhj 4233 4 the the DT cord-005646-xhx9pzhj 4233 5 withdrawal withdrawal NN cord-005646-xhx9pzhj 4233 6 of of IN cord-005646-xhx9pzhj 4233 7 the the DT cord-005646-xhx9pzhj 4233 8 ventficular ventficular NNP cord-005646-xhx9pzhj 4233 9 support support NN cord-005646-xhx9pzhj 4233 10 , , , cord-005646-xhx9pzhj 4233 11 but but CC cord-005646-xhx9pzhj 4233 12 unsucessfully unsucessfully RB cord-005646-xhx9pzhj 4233 13 despite despite IN cord-005646-xhx9pzhj 4233 14 the the DT cord-005646-xhx9pzhj 4233 15 increase increase NN cord-005646-xhx9pzhj 4233 16 ofinotropic ofinotropic JJ cord-005646-xhx9pzhj 4233 17 drugs drug NNS cord-005646-xhx9pzhj 4233 18 , , , cord-005646-xhx9pzhj 4233 19 so so RB cord-005646-xhx9pzhj 4233 20 she -PRON- PRP cord-005646-xhx9pzhj 4233 21 died die VBD cord-005646-xhx9pzhj 4233 22 . . . cord-005646-xhx9pzhj 4234 1 We -PRON- PRP cord-005646-xhx9pzhj 4234 2 think think VBP cord-005646-xhx9pzhj 4234 3 that that IN cord-005646-xhx9pzhj 4234 4 our -PRON- PRP$ cord-005646-xhx9pzhj 4234 5 patient patient NN cord-005646-xhx9pzhj 4234 6 is be VBZ cord-005646-xhx9pzhj 4234 7 a a DT cord-005646-xhx9pzhj 4234 8 good good JJ cord-005646-xhx9pzhj 4234 9 example example NN cord-005646-xhx9pzhj 4234 10 of of IN cord-005646-xhx9pzhj 4234 11 the the DT cord-005646-xhx9pzhj 4234 12 posibiti~ posibiti~ NNP cord-005646-xhx9pzhj 4234 13 to to TO cord-005646-xhx9pzhj 4234 14 mantain mantain VB cord-005646-xhx9pzhj 4235 1 x~ x~ XX cord-005646-xhx9pzhj 4236 1 ith ith IN cord-005646-xhx9pzhj 4236 2 ECMO ECMO NNP cord-005646-xhx9pzhj 4236 3 during during IN cord-005646-xhx9pzhj 4236 4 a a DT cord-005646-xhx9pzhj 4236 5 prolonged prolonged JJ cord-005646-xhx9pzhj 4236 6 period period NN cord-005646-xhx9pzhj 4236 7 of of IN cord-005646-xhx9pzhj 4236 8 time time NN cord-005646-xhx9pzhj 4236 9 a a DT cord-005646-xhx9pzhj 4236 10 potential potential JJ cord-005646-xhx9pzhj 4236 11 transplant transplant NN cord-005646-xhx9pzhj 4236 12 receiver receiver NN cord-005646-xhx9pzhj 4236 13 without without IN cord-005646-xhx9pzhj 4236 14 major major JJ cord-005646-xhx9pzhj 4236 15 complicatios complicatio NNS cord-005646-xhx9pzhj 4236 16 . . . cord-005646-xhx9pzhj 4237 1 Joan Joan NNP cord-005646-xhx9pzhj 4237 2 Wierema Wierema NNP cord-005646-xhx9pzhj 4237 3 ; ; : cord-005646-xhx9pzhj 4238 1 Ma0)an Ma0)an NNP cord-005646-xhx9pzhj 4238 2 Mourik Mourik NNP cord-005646-xhx9pzhj 4238 3 . . . cord-005646-xhx9pzhj 4239 1 Sophia Sophia NNP cord-005646-xhx9pzhj 4239 2 Children Children NNP cord-005646-xhx9pzhj 4239 3 's 's POS cord-005646-xhx9pzhj 4239 4 Hospital Hospital NNP cord-005646-xhx9pzhj 4239 5 , , , cord-005646-xhx9pzhj 4239 6 Department Department NNP cord-005646-xhx9pzhj 4239 7 of of IN cord-005646-xhx9pzhj 4239 8 Pediatric Pediatric NNP cord-005646-xhx9pzhj 4239 9 Surger Surger NNP cord-005646-xhx9pzhj 4239 10 , , , cord-005646-xhx9pzhj 4239 11 j j NNP cord-005646-xhx9pzhj 4239 12 , , , cord-005646-xhx9pzhj 4239 13 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 4239 14 , , , cord-005646-xhx9pzhj 4239 15 the the DT cord-005646-xhx9pzhj 4239 16 Netherlands Netherlands NNP cord-005646-xhx9pzhj 4239 17 . . . cord-005646-xhx9pzhj 4240 1 The the DT cord-005646-xhx9pzhj 4240 2 success success NN cord-005646-xhx9pzhj 4240 3 of of IN cord-005646-xhx9pzhj 4240 4 an an DT cord-005646-xhx9pzhj 4240 5 ECMO ECMO NNP cord-005646-xhx9pzhj 4240 6 program program NN cord-005646-xhx9pzhj 4240 7 is be VBZ cord-005646-xhx9pzhj 4240 8 heavily heavily RB cord-005646-xhx9pzhj 4240 9 determined determine VBN cord-005646-xhx9pzhj 4240 10 by by IN cord-005646-xhx9pzhj 4240 11 the the DT cord-005646-xhx9pzhj 4240 12 organizational organizational JJ cord-005646-xhx9pzhj 4240 13 structure structure NN cord-005646-xhx9pzhj 4240 14 and and CC cord-005646-xhx9pzhj 4240 15 the the DT cord-005646-xhx9pzhj 4240 16 daily daily JJ cord-005646-xhx9pzhj 4240 17 availability availability NN cord-005646-xhx9pzhj 4240 18 of of IN cord-005646-xhx9pzhj 4240 19 both both DT cord-005646-xhx9pzhj 4240 20 well well RB cord-005646-xhx9pzhj 4240 21 trained train VBN cord-005646-xhx9pzhj 4240 22 nurses nurse NNS cord-005646-xhx9pzhj 4240 23 and and CC cord-005646-xhx9pzhj 4240 24 physicians physician NNS cord-005646-xhx9pzhj 4240 25 . . . cord-005646-xhx9pzhj 4241 1 Until until IN cord-005646-xhx9pzhj 4241 2 now now RB cord-005646-xhx9pzhj 4241 3 there there EX cord-005646-xhx9pzhj 4241 4 is be VBZ cord-005646-xhx9pzhj 4241 5 no no DT cord-005646-xhx9pzhj 4241 6 general general JJ cord-005646-xhx9pzhj 4241 7 guideline guideline NN cord-005646-xhx9pzhj 4241 8 to to TO cord-005646-xhx9pzhj 4241 9 determine determine VB cord-005646-xhx9pzhj 4241 10 the the DT cord-005646-xhx9pzhj 4241 11 optimal optimal JJ cord-005646-xhx9pzhj 4241 12 training training NN cord-005646-xhx9pzhj 4241 13 schedule schedule NN cord-005646-xhx9pzhj 4241 14 to to TO cord-005646-xhx9pzhj 4241 15 set set VB cord-005646-xhx9pzhj 4241 16 up up RP cord-005646-xhx9pzhj 4241 17 an an DT cord-005646-xhx9pzhj 4241 18 ECMO ECMO NNP cord-005646-xhx9pzhj 4241 19 program program NN cord-005646-xhx9pzhj 4241 20 . . . cord-005646-xhx9pzhj 4242 1 Objective objective NN cord-005646-xhx9pzhj 4242 2 : : : cord-005646-xhx9pzhj 4243 1 To to TO cord-005646-xhx9pzhj 4243 2 evaluate evaluate VB cord-005646-xhx9pzhj 4243 3 the the DT cord-005646-xhx9pzhj 4243 4 set set NN cord-005646-xhx9pzhj 4243 5 - - HYPH cord-005646-xhx9pzhj 4243 6 up up NN cord-005646-xhx9pzhj 4243 7 of of IN cord-005646-xhx9pzhj 4243 8 an an DT cord-005646-xhx9pzhj 4243 9 ECMO ECMO NNP cord-005646-xhx9pzhj 4243 10 program program NN cord-005646-xhx9pzhj 4243 11 in in IN cord-005646-xhx9pzhj 4243 12 an an DT cord-005646-xhx9pzhj 4243 13 area area NN cord-005646-xhx9pzhj 4243 14 without without IN cord-005646-xhx9pzhj 4243 15 direct direct JJ cord-005646-xhx9pzhj 4243 16 availability availability NN cord-005646-xhx9pzhj 4243 17 of of IN cord-005646-xhx9pzhj 4243 18 perfusionists perfusionist NNS cord-005646-xhx9pzhj 4243 19 of of IN cord-005646-xhx9pzhj 4243 20 cardiothoracic cardiothoracic JJ cord-005646-xhx9pzhj 4243 21 surgeons surgeon NNS cord-005646-xhx9pzhj 4243 22 . . . cord-005646-xhx9pzhj 4244 1 Description description NN cord-005646-xhx9pzhj 4244 2 of of IN cord-005646-xhx9pzhj 4244 3 the the DT cord-005646-xhx9pzhj 4244 4 progress progress NN cord-005646-xhx9pzhj 4244 5 : : : cord-005646-xhx9pzhj 4244 6 During during IN cord-005646-xhx9pzhj 4244 7 the the DT cord-005646-xhx9pzhj 4244 8 preparation preparation NN cord-005646-xhx9pzhj 4244 9 of of IN cord-005646-xhx9pzhj 4244 10 the the DT cord-005646-xhx9pzhj 4244 11 ECMO ECMO NNP cord-005646-xhx9pzhj 4244 12 program program NN cord-005646-xhx9pzhj 4244 13 which which WDT cord-005646-xhx9pzhj 4244 14 started start VBD cord-005646-xhx9pzhj 4244 15 november november NNP cord-005646-xhx9pzhj 4244 16 1991 1991 CD cord-005646-xhx9pzhj 4244 17 , , , cord-005646-xhx9pzhj 4244 18 different different JJ cord-005646-xhx9pzhj 4244 19 phases phase NNS cord-005646-xhx9pzhj 4244 20 are be VBP cord-005646-xhx9pzhj 4244 21 identified identify VBN cord-005646-xhx9pzhj 4244 22 . . . cord-005646-xhx9pzhj 4245 1 First first JJ cord-005646-xhx9pzhj 4245 2 phase phase NN cord-005646-xhx9pzhj 4245 3 , , , cord-005646-xhx9pzhj 4245 4 acquisition acquisition NN cord-005646-xhx9pzhj 4245 5 of of IN cord-005646-xhx9pzhj 4245 6 experience experience NN cord-005646-xhx9pzhj 4245 7 by by IN cord-005646-xhx9pzhj 4245 8 training train VBG cord-005646-xhx9pzhj 4245 9 abroad abroad RB cord-005646-xhx9pzhj 4245 10 of of IN cord-005646-xhx9pzhj 4245 11 one one CD cord-005646-xhx9pzhj 4245 12 physician physician NN cord-005646-xhx9pzhj 4245 13 , , , cord-005646-xhx9pzhj 4245 14 staff staff NN cord-005646-xhx9pzhj 4245 15 member member NN cord-005646-xhx9pzhj 4245 16 of of IN cord-005646-xhx9pzhj 4245 17 the the DT cord-005646-xhx9pzhj 4245 18 ICU ICU NNP cord-005646-xhx9pzhj 4245 19 , , , cord-005646-xhx9pzhj 4245 20 physician physician NN cord-005646-xhx9pzhj 4245 21 acting acting NN cord-005646-xhx9pzhj 4245 22 as as IN cord-005646-xhx9pzhj 4245 23 a a DT cord-005646-xhx9pzhj 4245 24 fellow fellow NN cord-005646-xhx9pzhj 4245 25 and and CC cord-005646-xhx9pzhj 4245 26 one one CD cord-005646-xhx9pzhj 4245 27 ICU ICU NNP cord-005646-xhx9pzhj 4245 28 nurse nurse NN cord-005646-xhx9pzhj 4245 29 with with IN cord-005646-xhx9pzhj 4245 30 theprimary theprimary NNP cord-005646-xhx9pzhj 4245 31 task task NN cord-005646-xhx9pzhj 4245 32 to to TO cord-005646-xhx9pzhj 4245 33 serve serve VB cord-005646-xhx9pzhj 4245 34 as as IN cord-005646-xhx9pzhj 4245 35 an an DT cord-005646-xhx9pzhj 4245 36 ECMO ECMO NNP cord-005646-xhx9pzhj 4245 37 coordinator coordinator NN cord-005646-xhx9pzhj 4245 38 and and CC cord-005646-xhx9pzhj 4245 39 train train VB cord-005646-xhx9pzhj 4245 40 the the DT cord-005646-xhx9pzhj 4245 41 nursing nursing NN cord-005646-xhx9pzhj 4245 42 start start NN cord-005646-xhx9pzhj 4245 43 . . . cord-005646-xhx9pzhj 4246 1 In in IN cord-005646-xhx9pzhj 4246 2 the the DT cord-005646-xhx9pzhj 4246 3 second second JJ cord-005646-xhx9pzhj 4246 4 phase phase NN cord-005646-xhx9pzhj 4246 5 12 12 CD cord-005646-xhx9pzhj 4246 6 animal animal NN cord-005646-xhx9pzhj 4246 7 experiments experiment NNS cord-005646-xhx9pzhj 4246 8 were be VBD cord-005646-xhx9pzhj 4246 9 performed perform VBN cord-005646-xhx9pzhj 4246 10 by by IN cord-005646-xhx9pzhj 4246 11 2 2 CD cord-005646-xhx9pzhj 4246 12 paediatric paediatric JJ cord-005646-xhx9pzhj 4246 13 surgeons surgeon NNS cord-005646-xhx9pzhj 4246 14 , , , cord-005646-xhx9pzhj 4246 15 2 2 CD cord-005646-xhx9pzhj 4246 16 staff staff NN cord-005646-xhx9pzhj 4246 17 physicians physician NNS cord-005646-xhx9pzhj 4246 18 , , , cord-005646-xhx9pzhj 4246 19 2 2 CD cord-005646-xhx9pzhj 4246 20 fellows fellow NNS cord-005646-xhx9pzhj 4246 21 and and CC cord-005646-xhx9pzhj 4246 22 12 12 CD cord-005646-xhx9pzhj 4246 23 nurses nurse NNS cord-005646-xhx9pzhj 4246 24 . . . cord-005646-xhx9pzhj 4247 1 Third third JJ cord-005646-xhx9pzhj 4247 2 phase phase NN cord-005646-xhx9pzhj 4247 3 , , , cord-005646-xhx9pzhj 4247 4 start start VB cord-005646-xhx9pzhj 4247 5 of of IN cord-005646-xhx9pzhj 4247 6 the the DT cord-005646-xhx9pzhj 4247 7 actual actual JJ cord-005646-xhx9pzhj 4247 8 ECMO ECMO NNP cord-005646-xhx9pzhj 4247 9 program program NN cord-005646-xhx9pzhj 4247 10 , , , cord-005646-xhx9pzhj 4247 11 priming prime VBG cord-005646-xhx9pzhj 4247 12 by by IN cord-005646-xhx9pzhj 4247 13 one one CD cord-005646-xhx9pzhj 4247 14 trained train VBN cord-005646-xhx9pzhj 4247 15 nurse nurse NN cord-005646-xhx9pzhj 4247 16 and and CC cord-005646-xhx9pzhj 4247 17 ECMO ECMO NNP cord-005646-xhx9pzhj 4247 18 fellow fellow NN cord-005646-xhx9pzhj 4247 19 , , , cord-005646-xhx9pzhj 4247 20 daily daily JJ cord-005646-xhx9pzhj 4247 21 care care NN cord-005646-xhx9pzhj 4247 22 of of IN cord-005646-xhx9pzhj 4247 23 the the DT cord-005646-xhx9pzhj 4247 24 patient patient NN cord-005646-xhx9pzhj 4247 25 by by IN cord-005646-xhx9pzhj 4247 26 2 2 CD cord-005646-xhx9pzhj 4247 27 nurses nurse NNS cord-005646-xhx9pzhj 4247 28 , , , cord-005646-xhx9pzhj 4247 29 1 1 CD cord-005646-xhx9pzhj 4247 30 ICU ICU NNP cord-005646-xhx9pzhj 4247 31 nurse nurse NN cord-005646-xhx9pzhj 4247 32 taking take VBG cord-005646-xhx9pzhj 4247 33 care care NN cord-005646-xhx9pzhj 4247 34 of of IN cord-005646-xhx9pzhj 4247 35 the the DT cord-005646-xhx9pzhj 4247 36 patient patient NN cord-005646-xhx9pzhj 4247 37 related relate VBN cord-005646-xhx9pzhj 4247 38 activities activity NNS cord-005646-xhx9pzhj 4247 39 , , , cord-005646-xhx9pzhj 4247 40 1 1 CD cord-005646-xhx9pzhj 4247 41 ECMO ecmo NN cord-005646-xhx9pzhj 4247 42 trained train VBN cord-005646-xhx9pzhj 4247 43 nurse nurse NN cord-005646-xhx9pzhj 4247 44 taking take VBG cord-005646-xhx9pzhj 4247 45 care care NN cord-005646-xhx9pzhj 4247 46 of of IN cord-005646-xhx9pzhj 4247 47 the the DT cord-005646-xhx9pzhj 4247 48 circuit circuit NN cord-005646-xhx9pzhj 4247 49 . . . cord-005646-xhx9pzhj 4248 1 Fourth fourth JJ cord-005646-xhx9pzhj 4248 2 phase phase NN cord-005646-xhx9pzhj 4248 3 , , , cord-005646-xhx9pzhj 4248 4 transition transition NN cord-005646-xhx9pzhj 4248 5 of of IN cord-005646-xhx9pzhj 4248 6 the the DT cord-005646-xhx9pzhj 4248 7 tasks task NNS cord-005646-xhx9pzhj 4248 8 for for IN cord-005646-xhx9pzhj 4248 9 priming prime VBG cord-005646-xhx9pzhj 4248 10 the the DT cord-005646-xhx9pzhj 4248 11 system system NN cord-005646-xhx9pzhj 4248 12 from from IN cord-005646-xhx9pzhj 4248 13 the the DT cord-005646-xhx9pzhj 4248 14 ECMO ECMO NNP cord-005646-xhx9pzhj 4248 15 fellow fellow NN cord-005646-xhx9pzhj 4248 16 to to IN cord-005646-xhx9pzhj 4248 17 the the DT cord-005646-xhx9pzhj 4248 18 ECMO ECMO NNP cord-005646-xhx9pzhj 4248 19 nurse nurse NN cord-005646-xhx9pzhj 4248 20 and and CC cord-005646-xhx9pzhj 4248 21 changing change VBG cord-005646-xhx9pzhj 4248 22 daily daily JJ cord-005646-xhx9pzhj 4248 23 care care NN cord-005646-xhx9pzhj 4248 24 for for IN cord-005646-xhx9pzhj 4248 25 the the DT cord-005646-xhx9pzhj 4248 26 ECMO ECMO NNP cord-005646-xhx9pzhj 4248 27 patient patient NN cord-005646-xhx9pzhj 4248 28 now now RB cord-005646-xhx9pzhj 4248 29 including include VBG cord-005646-xhx9pzhj 4248 30 the the DT cord-005646-xhx9pzhj 4248 31 circuit circuit NN cord-005646-xhx9pzhj 4248 32 by by IN cord-005646-xhx9pzhj 4248 33 1 1 CD cord-005646-xhx9pzhj 4248 34 trained train VBN cord-005646-xhx9pzhj 4248 35 ICU ICU NNP cord-005646-xhx9pzhj 4248 36 nurse nurse NN cord-005646-xhx9pzhj 4248 37 with with IN cord-005646-xhx9pzhj 4248 38 special special JJ cord-005646-xhx9pzhj 4248 39 legislation legislation NN cord-005646-xhx9pzhj 4248 40 for for IN cord-005646-xhx9pzhj 4248 41 ECMO ECMO NNP cord-005646-xhx9pzhj 4248 42 . . . cord-005646-xhx9pzhj 4249 1 Ongoing ongoing JJ cord-005646-xhx9pzhj 4249 2 training training NN cord-005646-xhx9pzhj 4249 3 of of IN cord-005646-xhx9pzhj 4249 4 6 6 CD cord-005646-xhx9pzhj 4249 5 to to TO cord-005646-xhx9pzhj 4249 6 8 8 CD cord-005646-xhx9pzhj 4249 7 nurses nurse NNS cord-005646-xhx9pzhj 4249 8 working work VBG cord-005646-xhx9pzhj 4249 9 for for IN cord-005646-xhx9pzhj 4249 10 at at RB cord-005646-xhx9pzhj 4249 11 least least JJS cord-005646-xhx9pzhj 4249 12 half half PDT cord-005646-xhx9pzhj 4249 13 a a DT cord-005646-xhx9pzhj 4249 14 year year NN cord-005646-xhx9pzhj 4249 15 in in IN cord-005646-xhx9pzhj 4249 16 the the DT cord-005646-xhx9pzhj 4249 17 ICU ICU NNP cord-005646-xhx9pzhj 4249 18 . . . cord-005646-xhx9pzhj 4250 1 During during IN cord-005646-xhx9pzhj 4250 2 an an DT cord-005646-xhx9pzhj 4250 3 ECMO ECMO NNP cord-005646-xhx9pzhj 4250 4 run run VBP cord-005646-xhx9pzhj 4250 5 direct direct JJ cord-005646-xhx9pzhj 4250 6 contact contact NN cord-005646-xhx9pzhj 4250 7 between between IN cord-005646-xhx9pzhj 4250 8 the the DT cord-005646-xhx9pzhj 4250 9 ECMO ECMO NNP cord-005646-xhx9pzhj 4250 10 nurse nurse NN cord-005646-xhx9pzhj 4250 11 and and CC cord-005646-xhx9pzhj 4250 12 one one CD cord-005646-xhx9pzhj 4250 13 of of IN cord-005646-xhx9pzhj 4250 14 the the DT cord-005646-xhx9pzhj 4250 15 staff staff NN cord-005646-xhx9pzhj 4250 16 members member NNS cord-005646-xhx9pzhj 4250 17 ; ; : cord-005646-xhx9pzhj 4250 18 Patient Patient NNP cord-005646-xhx9pzhj 4250 19 data datum NNS cord-005646-xhx9pzhj 4250 20 : : : cord-005646-xhx9pzhj 4250 21 In in IN cord-005646-xhx9pzhj 4250 22 a a DT cord-005646-xhx9pzhj 4250 23 4 4 CD cord-005646-xhx9pzhj 4250 24 year year NN cord-005646-xhx9pzhj 4250 25 period period NN cord-005646-xhx9pzhj 4250 26 52 52 CD cord-005646-xhx9pzhj 4250 27 neonatal neonatal JJ cord-005646-xhx9pzhj 4250 28 ECMO ecmo NN cord-005646-xhx9pzhj 4250 29 cases case NNS cord-005646-xhx9pzhj 4250 30 were be VBD cord-005646-xhx9pzhj 4250 31 performed perform VBN cord-005646-xhx9pzhj 4250 32 with with IN cord-005646-xhx9pzhj 4250 33 an an DT cord-005646-xhx9pzhj 4250 34 overall overall JJ cord-005646-xhx9pzhj 4250 35 mortality mortality NN cord-005646-xhx9pzhj 4250 36 of of IN cord-005646-xhx9pzhj 4250 37 74 74 CD cord-005646-xhx9pzhj 4250 38 % % NN cord-005646-xhx9pzhj 4250 39 , , , cord-005646-xhx9pzhj 4250 40 ranging range VBG cord-005646-xhx9pzhj 4250 41 from from IN cord-005646-xhx9pzhj 4250 42 over over IN cord-005646-xhx9pzhj 4250 43 95 95 CD cord-005646-xhx9pzhj 4250 44 % % NN cord-005646-xhx9pzhj 4250 45 in in IN cord-005646-xhx9pzhj 4250 46 meconium meconium NN cord-005646-xhx9pzhj 4250 47 aspiration aspiration NN cord-005646-xhx9pzhj 4250 48 to to IN cord-005646-xhx9pzhj 4250 49 45 45 CD cord-005646-xhx9pzhj 4250 50 % % NN cord-005646-xhx9pzhj 4250 51 in in IN cord-005646-xhx9pzhj 4250 52 congenital congenital JJ cord-005646-xhx9pzhj 4250 53 diaphragmatic diaphragmatic JJ cord-005646-xhx9pzhj 4250 54 hernia hernia NN cord-005646-xhx9pzhj 4250 55 . . . cord-005646-xhx9pzhj 4251 1 In in IN cord-005646-xhx9pzhj 4251 2 7 7 CD cord-005646-xhx9pzhj 4251 3 other other JJ cord-005646-xhx9pzhj 4251 4 patients patient NNS cord-005646-xhx9pzhj 4251 5 pediatric pediatric JJ cord-005646-xhx9pzhj 4251 6 ECMO ecmo NN cord-005646-xhx9pzhj 4252 1 ( ( -LRB- cord-005646-xhx9pzhj 4252 2 age age NN cord-005646-xhx9pzhj 4252 3 range range NN cord-005646-xhx9pzhj 4252 4 1 1 CD cord-005646-xhx9pzhj 4252 5 month month NN cord-005646-xhx9pzhj 4252 6 -14 -14 CD cord-005646-xhx9pzhj 4252 7 months month NNS cord-005646-xhx9pzhj 4252 8 ) ) -RRB- cord-005646-xhx9pzhj 4252 9 mortality mortality NN cord-005646-xhx9pzhj 4252 10 was be VBD cord-005646-xhx9pzhj 4252 11 50 50 CD cord-005646-xhx9pzhj 4252 12 % % NN cord-005646-xhx9pzhj 4252 13 . . . cord-005646-xhx9pzhj 4253 1 Conclusions conclusion NNS cord-005646-xhx9pzhj 4253 2 : : : cord-005646-xhx9pzhj 4254 1 ECMO ECMO NNP cord-005646-xhx9pzhj 4254 2 can can MD cord-005646-xhx9pzhj 4254 3 be be VB cord-005646-xhx9pzhj 4254 4 established establish VBN cord-005646-xhx9pzhj 4254 5 without without IN cord-005646-xhx9pzhj 4254 6 perfusionists perfusionist NNS cord-005646-xhx9pzhj 4254 7 or or CC cord-005646-xhx9pzhj 4254 8 cardio cardio JJ cord-005646-xhx9pzhj 4254 9 surgical surgical NN cord-005646-xhx9pzhj 4254 10 back back RB cord-005646-xhx9pzhj 4254 11 up up RP cord-005646-xhx9pzhj 4254 12 once once IN cord-005646-xhx9pzhj 4254 13 a a DT cord-005646-xhx9pzhj 4254 14 predetermined predetermine VBN cord-005646-xhx9pzhj 4254 15 training training NN cord-005646-xhx9pzhj 4254 16 schedule schedule NN cord-005646-xhx9pzhj 4254 17 is be VBZ cord-005646-xhx9pzhj 4254 18 available available JJ cord-005646-xhx9pzhj 4254 19 , , , cord-005646-xhx9pzhj 4254 20 resulting result VBG cord-005646-xhx9pzhj 4254 21 in in IN cord-005646-xhx9pzhj 4254 22 comparable comparable JJ cord-005646-xhx9pzhj 4254 23 results result NNS cord-005646-xhx9pzhj 4254 24 with with IN cord-005646-xhx9pzhj 4254 25 the the DT cord-005646-xhx9pzhj 4254 26 international international JJ cord-005646-xhx9pzhj 4254 27 ECMO ecmo NN cord-005646-xhx9pzhj 4254 28 registry registry NN cord-005646-xhx9pzhj 4254 29 both both CC cord-005646-xhx9pzhj 4254 30 for for IN cord-005646-xhx9pzhj 4254 31 neonatal neonatal JJ cord-005646-xhx9pzhj 4254 32 as as RB cord-005646-xhx9pzhj 4254 33 well well RB cord-005646-xhx9pzhj 4254 34 as as IN cord-005646-xhx9pzhj 4254 35 for for IN cord-005646-xhx9pzhj 4254 36 pediatric pediatric JJ cord-005646-xhx9pzhj 4254 37 cases case NNS cord-005646-xhx9pzhj 4254 38 . . . cord-005646-xhx9pzhj 4255 1 Mechanical mechanical JJ cord-005646-xhx9pzhj 4255 2 ventilation ventilation NN cord-005646-xhx9pzhj 4255 3 at at IN cord-005646-xhx9pzhj 4255 4 home home NN cord-005646-xhx9pzhj 4255 5 makes make VBZ cord-005646-xhx9pzhj 4255 6 normal normal JJ cord-005646-xhx9pzhj 4255 7 development development NN cord-005646-xhx9pzhj 4255 8 of of IN cord-005646-xhx9pzhj 4255 9 the the DT cord-005646-xhx9pzhj 4255 10 child child NN cord-005646-xhx9pzhj 4255 11 with with IN cord-005646-xhx9pzhj 4255 12 chronic chronic JJ cord-005646-xhx9pzhj 4255 13 respiratory respiratory JJ cord-005646-xhx9pzhj 4255 14 failure failure NN cord-005646-xhx9pzhj 4255 15 possible possible JJ cord-005646-xhx9pzhj 4255 16 . . . cord-005646-xhx9pzhj 4256 1 The the DT cord-005646-xhx9pzhj 4256 2 parents parent NNS cord-005646-xhx9pzhj 4256 3 must must MD cord-005646-xhx9pzhj 4256 4 be be VB cord-005646-xhx9pzhj 4256 5 encouraged encourage VBN cord-005646-xhx9pzhj 4256 6 to to TO cord-005646-xhx9pzhj 4256 7 accept accept VB cord-005646-xhx9pzhj 4256 8 the the DT cord-005646-xhx9pzhj 4256 9 treatment treatment NN cord-005646-xhx9pzhj 4256 10 at at IN cord-005646-xhx9pzhj 4256 11 home home NN cord-005646-xhx9pzhj 4256 12 ; ; : cord-005646-xhx9pzhj 4256 13 therefore therefore RB cord-005646-xhx9pzhj 4256 14 , , , cord-005646-xhx9pzhj 4256 15 they -PRON- PRP cord-005646-xhx9pzhj 4256 16 should should MD cord-005646-xhx9pzhj 4256 17 be be VB cord-005646-xhx9pzhj 4256 18 enabled enable VBN cord-005646-xhx9pzhj 4256 19 to to TO cord-005646-xhx9pzhj 4256 20 take take VB cord-005646-xhx9pzhj 4256 21 care care NN cord-005646-xhx9pzhj 4256 22 of of IN cord-005646-xhx9pzhj 4256 23 their -PRON- PRP$ cord-005646-xhx9pzhj 4256 24 children child NNS cord-005646-xhx9pzhj 4256 25 all all RB cord-005646-xhx9pzhj 4256 26 by by IN cord-005646-xhx9pzhj 4256 27 themselves -PRON- PRP cord-005646-xhx9pzhj 4256 28 and and CC cord-005646-xhx9pzhj 4256 29 the the DT cord-005646-xhx9pzhj 4256 30 continuous continuous JJ cord-005646-xhx9pzhj 4256 31 professional professional JJ cord-005646-xhx9pzhj 4256 32 support support NN cord-005646-xhx9pzhj 4256 33 has have VBZ cord-005646-xhx9pzhj 4256 34 to to TO cord-005646-xhx9pzhj 4256 35 be be VB cord-005646-xhx9pzhj 4256 36 offered offer VBN cord-005646-xhx9pzhj 4256 37 to to IN cord-005646-xhx9pzhj 4256 38 them -PRON- PRP cord-005646-xhx9pzhj 4256 39 . . . cord-005646-xhx9pzhj 4257 1 It -PRON- PRP cord-005646-xhx9pzhj 4257 2 must must MD cord-005646-xhx9pzhj 4257 3 be be VB cord-005646-xhx9pzhj 4257 4 stressed stress VBN cord-005646-xhx9pzhj 4257 5 that that IN cord-005646-xhx9pzhj 4257 6 the the DT cord-005646-xhx9pzhj 4257 7 nurse nurse NN cord-005646-xhx9pzhj 4257 8 is be VBZ cord-005646-xhx9pzhj 4257 9 the the DT cord-005646-xhx9pzhj 4257 10 link link NN cord-005646-xhx9pzhj 4257 11 between between IN cord-005646-xhx9pzhj 4257 12 the the DT cord-005646-xhx9pzhj 4257 13 diseased diseased JJ cord-005646-xhx9pzhj 4257 14 child child NN cord-005646-xhx9pzhj 4257 15 and and CC cord-005646-xhx9pzhj 4257 16 his -PRON- PRP$ cord-005646-xhx9pzhj 4257 17 family family NN cord-005646-xhx9pzhj 4257 18 introducing introduce VBG cord-005646-xhx9pzhj 4257 19 them -PRON- PRP cord-005646-xhx9pzhj 4257 20 into into IN cord-005646-xhx9pzhj 4257 21 the the DT cord-005646-xhx9pzhj 4257 22 process process NN cord-005646-xhx9pzhj 4257 23 of of IN cord-005646-xhx9pzhj 4257 24 the the DT cord-005646-xhx9pzhj 4257 25 medical medical JJ cord-005646-xhx9pzhj 4257 26 care care NN cord-005646-xhx9pzhj 4257 27 at at IN cord-005646-xhx9pzhj 4257 28 home home NN cord-005646-xhx9pzhj 4257 29 . . . cord-005646-xhx9pzhj 4258 1 All all PDT cord-005646-xhx9pzhj 4258 2 the the DT cord-005646-xhx9pzhj 4258 3 equipment equipment NN cord-005646-xhx9pzhj 4258 4 needed need VBN cord-005646-xhx9pzhj 4258 5 for for IN cord-005646-xhx9pzhj 4258 6 the the DT cord-005646-xhx9pzhj 4258 7 mechanical mechanical JJ cord-005646-xhx9pzhj 4258 8 ventilation ventilation NN cord-005646-xhx9pzhj 4258 9 of of IN cord-005646-xhx9pzhj 4258 10 the the DT cord-005646-xhx9pzhj 4258 11 child child NN cord-005646-xhx9pzhj 4258 12 at at IN cord-005646-xhx9pzhj 4258 13 home home NN cord-005646-xhx9pzhj 4258 14 ( ( -LRB- cord-005646-xhx9pzhj 4258 15 ventilator ventilator NN cord-005646-xhx9pzhj 4258 16 , , , cord-005646-xhx9pzhj 4258 17 suction suction NN cord-005646-xhx9pzhj 4258 18 device device NN cord-005646-xhx9pzhj 4258 19 , , , cord-005646-xhx9pzhj 4258 20 pulse pulse NN cord-005646-xhx9pzhj 4258 21 oxymeter oxymeter RB cord-005646-xhx9pzhj 4258 22 , , , cord-005646-xhx9pzhj 4258 23 oxygen oxygen NN cord-005646-xhx9pzhj 4258 24 tanks tank NNS cord-005646-xhx9pzhj 4258 25 ) ) -RRB- cord-005646-xhx9pzhj 4258 26 has have VBZ cord-005646-xhx9pzhj 4258 27 to to TO cord-005646-xhx9pzhj 4258 28 be be VB cord-005646-xhx9pzhj 4258 29 provided provide VBN cord-005646-xhx9pzhj 4258 30 before before IN cord-005646-xhx9pzhj 4258 31 the the DT cord-005646-xhx9pzhj 4258 32 child child NN cord-005646-xhx9pzhj 4258 33 is be VBZ cord-005646-xhx9pzhj 4258 34 discharged discharge VBN cord-005646-xhx9pzhj 4258 35 . . . cord-005646-xhx9pzhj 4259 1 It -PRON- PRP cord-005646-xhx9pzhj 4259 2 is be VBZ cord-005646-xhx9pzhj 4259 3 paid pay VBN cord-005646-xhx9pzhj 4259 4 by by IN cord-005646-xhx9pzhj 4259 5 the the DT cord-005646-xhx9pzhj 4259 6 national national JJ cord-005646-xhx9pzhj 4259 7 insurance insurance NN cord-005646-xhx9pzhj 4259 8 company company NN cord-005646-xhx9pzhj 4259 9 . . . cord-005646-xhx9pzhj 4260 1 The the DT cord-005646-xhx9pzhj 4260 2 maintainance maintainance NN cord-005646-xhx9pzhj 4260 3 service service NN cord-005646-xhx9pzhj 4260 4 workers worker NNS cord-005646-xhx9pzhj 4260 5 will will MD cord-005646-xhx9pzhj 4260 6 make make VB cord-005646-xhx9pzhj 4260 7 the the DT cord-005646-xhx9pzhj 4260 8 necessary necessary JJ cord-005646-xhx9pzhj 4260 9 installations installation NNS cord-005646-xhx9pzhj 4260 10 available available JJ cord-005646-xhx9pzhj 4260 11 and and CC cord-005646-xhx9pzhj 4260 12 they -PRON- PRP cord-005646-xhx9pzhj 4260 13 will will MD cord-005646-xhx9pzhj 4260 14 renew renew VB cord-005646-xhx9pzhj 4260 15 oxygen oxygen NN cord-005646-xhx9pzhj 4260 16 and and CC cord-005646-xhx9pzhj 4260 17 compressed compress VBN cord-005646-xhx9pzhj 4260 18 air air NN cord-005646-xhx9pzhj 4260 19 weekly weekly NN cord-005646-xhx9pzhj 4260 20 . . . cord-005646-xhx9pzhj 4261 1 The the DT cord-005646-xhx9pzhj 4261 2 ventilation ventilation NN cord-005646-xhx9pzhj 4261 3 assembly assembly NN cord-005646-xhx9pzhj 4261 4 must must MD cord-005646-xhx9pzhj 4261 5 not not RB cord-005646-xhx9pzhj 4261 6 interfere interfere VB cord-005646-xhx9pzhj 4261 7 with with IN cord-005646-xhx9pzhj 4261 8 the the DT cord-005646-xhx9pzhj 4261 9 childs childs NN cord-005646-xhx9pzhj 4261 10 activities activity NNS cord-005646-xhx9pzhj 4261 11 . . . cord-005646-xhx9pzhj 4262 1 The the DT cord-005646-xhx9pzhj 4262 2 related related JJ cord-005646-xhx9pzhj 4262 3 dispensary dispensary NN cord-005646-xhx9pzhj 4262 4 and and CC cord-005646-xhx9pzhj 4262 5 nursing nursing NN cord-005646-xhx9pzhj 4262 6 service service NN cord-005646-xhx9pzhj 4262 7 should should MD cord-005646-xhx9pzhj 4262 8 be be VB cord-005646-xhx9pzhj 4262 9 notified notify VBN cord-005646-xhx9pzhj 4262 10 of of IN cord-005646-xhx9pzhj 4262 11 the the DT cord-005646-xhx9pzhj 4262 12 child child NN cord-005646-xhx9pzhj 4262 13 's 's POS cord-005646-xhx9pzhj 4262 14 condition condition NN cord-005646-xhx9pzhj 4262 15 and and CC cord-005646-xhx9pzhj 4262 16 the the DT cord-005646-xhx9pzhj 4262 17 list list NN cord-005646-xhx9pzhj 4262 18 of of IN cord-005646-xhx9pzhj 4262 19 the the DT cord-005646-xhx9pzhj 4262 20 required require VBN cord-005646-xhx9pzhj 4262 21 material material NN cord-005646-xhx9pzhj 4262 22 ( ( -LRB- cord-005646-xhx9pzhj 4262 23 suction suction NN cord-005646-xhx9pzhj 4262 24 tubes tube NNS cord-005646-xhx9pzhj 4262 25 , , , cord-005646-xhx9pzhj 4262 26 cannulas cannula NNS cord-005646-xhx9pzhj 4262 27 , , , cord-005646-xhx9pzhj 4262 28 desinfectants desinfectant NNS cord-005646-xhx9pzhj 4262 29 etc etc FW cord-005646-xhx9pzhj 4262 30 . . . cord-005646-xhx9pzhj 4262 31 ) ) -RRB- cord-005646-xhx9pzhj 4262 32 has have VBZ cord-005646-xhx9pzhj 4262 33 to to TO cord-005646-xhx9pzhj 4262 34 be be VB cord-005646-xhx9pzhj 4262 35 made make VBN cord-005646-xhx9pzhj 4262 36 . . . cord-005646-xhx9pzhj 4263 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 4263 2 experience experience NN cord-005646-xhx9pzhj 4263 3 is be VBZ cord-005646-xhx9pzhj 4263 4 so so RB cord-005646-xhx9pzhj 4263 5 far far RB cord-005646-xhx9pzhj 4263 6 -from -from . cord-005646-xhx9pzhj 4264 1 the the DT cord-005646-xhx9pzhj 4264 2 nursing nursing NN cord-005646-xhx9pzhj 4264 3 and and CC cord-005646-xhx9pzhj 4264 4 medical medical JJ cord-005646-xhx9pzhj 4264 5 point point NN cord-005646-xhx9pzhj 4264 6 of of IN cord-005646-xhx9pzhj 4264 7 view view NN cord-005646-xhx9pzhj 4265 1 -satisfactory -satisfactory : cord-005646-xhx9pzhj 4265 2 , , , cord-005646-xhx9pzhj 4265 3 however however RB cord-005646-xhx9pzhj 4265 4 the the DT cord-005646-xhx9pzhj 4265 5 social social JJ cord-005646-xhx9pzhj 4265 6 status status NN cord-005646-xhx9pzhj 4265 7 of of IN cord-005646-xhx9pzhj 4265 8 the the DT cord-005646-xhx9pzhj 4265 9 parents parent NNS cord-005646-xhx9pzhj 4265 10 needs need VBZ cord-005646-xhx9pzhj 4265 11 further further JJ cord-005646-xhx9pzhj 4265 12 regulations regulation NNS cord-005646-xhx9pzhj 4265 13 , , , cord-005646-xhx9pzhj 4265 14 OMPHALOCELE OMPHALOCELE NNP cord-005646-xhx9pzhj 4265 15 . . . cord-005646-xhx9pzhj 4266 1 Mourik Mourik NNP cord-005646-xhx9pzhj 4266 2 M M NNP cord-005646-xhx9pzhj 4266 3 , , , cord-005646-xhx9pzhj 4266 4 Sophia Sophia NNP cord-005646-xhx9pzhj 4266 5 Children Children NNP cord-005646-xhx9pzhj 4266 6 's 's POS cord-005646-xhx9pzhj 4266 7 Hospital Hospital NNP cord-005646-xhx9pzhj 4266 8 , , , cord-005646-xhx9pzhj 4266 9 Department Department NNP cord-005646-xhx9pzhj 4266 10 of of IN cord-005646-xhx9pzhj 4266 11 Pediatric Pediatric NNP cord-005646-xhx9pzhj 4266 12 Surgery Surgery NNP cord-005646-xhx9pzhj 4266 13 , , , cord-005646-xhx9pzhj 4266 14 Rotterdam Rotterdam NNP cord-005646-xhx9pzhj 4266 15 , , , cord-005646-xhx9pzhj 4266 16 the the DT cord-005646-xhx9pzhj 4266 17 Netherlands Netherlands NNP cord-005646-xhx9pzhj 4266 18 . . . cord-005646-xhx9pzhj 4267 1 In in IN cord-005646-xhx9pzhj 4267 2 patients patient NNS cord-005646-xhx9pzhj 4267 3 with with IN cord-005646-xhx9pzhj 4267 4 ( ( -LRB- cord-005646-xhx9pzhj 4267 5 giant giant JJ cord-005646-xhx9pzhj 4267 6 ) ) -RRB- cord-005646-xhx9pzhj 4267 7 omphalocde omphalocde JJ cord-005646-xhx9pzhj 4267 8 operative operative JJ cord-005646-xhx9pzhj 4267 9 closure closure NN cord-005646-xhx9pzhj 4267 10 is be VBZ cord-005646-xhx9pzhj 4267 11 impossible impossible JJ cord-005646-xhx9pzhj 4267 12 due due IN cord-005646-xhx9pzhj 4267 13 to to IN cord-005646-xhx9pzhj 4267 14 the the DT cord-005646-xhx9pzhj 4267 15 lack lack NN cord-005646-xhx9pzhj 4267 16 of of IN cord-005646-xhx9pzhj 4267 17 intra intra JJ cord-005646-xhx9pzhj 4267 18 - - JJ cord-005646-xhx9pzhj 4267 19 abdominal abdominal JJ cord-005646-xhx9pzhj 4267 20 space space NN cord-005646-xhx9pzhj 4267 21 and and CC cord-005646-xhx9pzhj 4267 22 a a DT cord-005646-xhx9pzhj 4267 23 variable variable JJ cord-005646-xhx9pzhj 4267 24 degree degree NN cord-005646-xhx9pzhj 4267 25 of of IN cord-005646-xhx9pzhj 4267 26 pulmonary pulmonary JJ cord-005646-xhx9pzhj 4267 27 hypoplasia hypoplasia NN cord-005646-xhx9pzhj 4267 28 . . . cord-005646-xhx9pzhj 4268 1 Consequently consequently RB cord-005646-xhx9pzhj 4268 2 conservative conservative JJ cord-005646-xhx9pzhj 4268 3 treatment treatment NN cord-005646-xhx9pzhj 4268 4 allowing allow VBG cord-005646-xhx9pzhj 4268 5 epithelialization epithelialization NN cord-005646-xhx9pzhj 4268 6 is be VBZ cord-005646-xhx9pzhj 4268 7 the the DT cord-005646-xhx9pzhj 4268 8 treatment treatment NN cord-005646-xhx9pzhj 4268 9 of of IN cord-005646-xhx9pzhj 4268 10 choice choice NN cord-005646-xhx9pzhj 4268 11 with with IN cord-005646-xhx9pzhj 4268 12 a a DT cord-005646-xhx9pzhj 4268 13 high high JJ cord-005646-xhx9pzhj 4268 14 risk risk NN cord-005646-xhx9pzhj 4268 15 of of IN cord-005646-xhx9pzhj 4268 16 infection infection NN cord-005646-xhx9pzhj 4269 1 and/or and/or CC cord-005646-xhx9pzhj 4269 2 sepsis sepsis NN cord-005646-xhx9pzhj 4269 3 due due IN cord-005646-xhx9pzhj 4269 4 to to IN cord-005646-xhx9pzhj 4269 5 a a DT cord-005646-xhx9pzhj 4269 6 sometimes sometimes RB cord-005646-xhx9pzhj 4269 7 very very RB cord-005646-xhx9pzhj 4269 8 long long RB cord-005646-xhx9pzhj 4269 9 stay stay NN cord-005646-xhx9pzhj 4269 10 in in IN cord-005646-xhx9pzhj 4269 11 the the DT cord-005646-xhx9pzhj 4269 12 ICU ICU NNP cord-005646-xhx9pzhj 4269 13 . . . cord-005646-xhx9pzhj 4270 1 This this DT cord-005646-xhx9pzhj 4270 2 conservative conservative JJ cord-005646-xhx9pzhj 4270 3 treatment treatment NN cord-005646-xhx9pzhj 4270 4 consists consist VBZ cord-005646-xhx9pzhj 4270 5 of of IN cord-005646-xhx9pzhj 4270 6 daily daily JJ cord-005646-xhx9pzhj 4270 7 application application NN cord-005646-xhx9pzhj 4270 8 of of IN cord-005646-xhx9pzhj 4270 9 an an DT cord-005646-xhx9pzhj 4270 10 antibiotic antibiotic JJ cord-005646-xhx9pzhj 4270 11 containing contain VBG cord-005646-xhx9pzhj 4270 12 powder powder NN cord-005646-xhx9pzhj 4270 13 on on IN cord-005646-xhx9pzhj 4270 14 the the DT cord-005646-xhx9pzhj 4270 15 cele cele NN cord-005646-xhx9pzhj 4270 16 which which WDT cord-005646-xhx9pzhj 4270 17 is be VBZ cord-005646-xhx9pzhj 4270 18 covered cover VBN cord-005646-xhx9pzhj 4270 19 by by IN cord-005646-xhx9pzhj 4270 20 sterile sterile JJ cord-005646-xhx9pzhj 4270 21 gauzes gauze NNS cord-005646-xhx9pzhj 4270 22 . . . cord-005646-xhx9pzhj 4271 1 Furthermore furthermore RB cord-005646-xhx9pzhj 4271 2 the the DT cord-005646-xhx9pzhj 4271 3 enteral enteral NN cord-005646-xhx9pzhj 4271 4 intake intake NN cord-005646-xhx9pzhj 4271 5 is be VBZ cord-005646-xhx9pzhj 4271 6 started start VBN cord-005646-xhx9pzhj 4271 7 as as RB cord-005646-xhx9pzhj 4271 8 soon soon RB cord-005646-xhx9pzhj 4271 9 possible possible JJ cord-005646-xhx9pzhj 4271 10 . . . cord-005646-xhx9pzhj 4272 1 Objective objective NN cord-005646-xhx9pzhj 4272 2 : : : cord-005646-xhx9pzhj 4272 3 To to TO cord-005646-xhx9pzhj 4272 4 evaluate evaluate VB cord-005646-xhx9pzhj 4272 5 whether whether IN cord-005646-xhx9pzhj 4272 6 this this DT cord-005646-xhx9pzhj 4272 7 treatment treatment NN cord-005646-xhx9pzhj 4272 8 renders render VBZ cord-005646-xhx9pzhj 4272 9 a a DT cord-005646-xhx9pzhj 4272 10 high high JJ cord-005646-xhx9pzhj 4272 11 risk risk NN cord-005646-xhx9pzhj 4272 12 for for IN cord-005646-xhx9pzhj 4272 13 serious serious JJ cord-005646-xhx9pzhj 4272 14 infections infection NNS cord-005646-xhx9pzhj 4272 15 . . . cord-005646-xhx9pzhj 4273 1 Patient patient JJ cord-005646-xhx9pzhj 4273 2 characteristics characteristic NNS cord-005646-xhx9pzhj 4274 1 : : : cord-005646-xhx9pzhj 4274 2 In in IN cord-005646-xhx9pzhj 4274 3 a a DT cord-005646-xhx9pzhj 4274 4 10 10 CD cord-005646-xhx9pzhj 4274 5 year year NN cord-005646-xhx9pzhj 4274 6 period period NN cord-005646-xhx9pzhj 4274 7 23 23 CD cord-005646-xhx9pzhj 4274 8 patients patient NNS cord-005646-xhx9pzhj 4274 9 with with IN cord-005646-xhx9pzhj 4274 10 a a DT cord-005646-xhx9pzhj 4274 11 giant giant JJ cord-005646-xhx9pzhj 4274 12 omphalocele omphalocele NNS cord-005646-xhx9pzhj 4274 13 were be VBD cord-005646-xhx9pzhj 4274 14 admitted admit VBN cord-005646-xhx9pzhj 4274 15 ; ; : cord-005646-xhx9pzhj 4274 16 mean mean VB cord-005646-xhx9pzhj 4274 17 birth birth NN cord-005646-xhx9pzhj 4274 18 weight weight NN cord-005646-xhx9pzhj 4274 19 2800 2800 CD cord-005646-xhx9pzhj 4274 20 g g NN cord-005646-xhx9pzhj 4274 21 ( ( -LRB- cord-005646-xhx9pzhj 4274 22 1500 1500 CD cord-005646-xhx9pzhj 4274 23 - - SYM cord-005646-xhx9pzhj 4274 24 3990 3990 CD cord-005646-xhx9pzhj 4274 25 g g NN cord-005646-xhx9pzhj 4274 26 ) ) -RRB- cord-005646-xhx9pzhj 4274 27 mean mean VB cord-005646-xhx9pzhj 4274 28 gestational gestational JJ cord-005646-xhx9pzhj 4274 29 age age NN cord-005646-xhx9pzhj 4274 30 38.5 38.5 CD cord-005646-xhx9pzhj 4274 31 ( ( -LRB- cord-005646-xhx9pzhj 4274 32 33 33 CD cord-005646-xhx9pzhj 4274 33 - - SYM cord-005646-xhx9pzhj 4274 34 42 42 CD cord-005646-xhx9pzhj 4274 35 weeks week NNS cord-005646-xhx9pzhj 4274 36 ) ) -RRB- cord-005646-xhx9pzhj 4274 37 . . . cord-005646-xhx9pzhj 4275 1 Overall overall JJ cord-005646-xhx9pzhj 4275 2 mortality mortality NN cord-005646-xhx9pzhj 4275 3 6 6 CD cord-005646-xhx9pzhj 4275 4 ( ( -LRB- cord-005646-xhx9pzhj 4275 5 19 19 CD cord-005646-xhx9pzhj 4275 6 % % NN cord-005646-xhx9pzhj 4275 7 ) ) -RRB- cord-005646-xhx9pzhj 4275 8 . . . cord-005646-xhx9pzhj 4276 1 11 11 CD cord-005646-xhx9pzhj 4276 2 patients patient NNS cord-005646-xhx9pzhj 4276 3 had have VBD cord-005646-xhx9pzhj 4276 4 to to TO cord-005646-xhx9pzhj 4276 5 be be VB cord-005646-xhx9pzhj 4276 6 ventilated ventilate VBN cord-005646-xhx9pzhj 4276 7 for for IN cord-005646-xhx9pzhj 4276 8 a a DT cord-005646-xhx9pzhj 4276 9 median median JJ cord-005646-xhx9pzhj 4276 10 duration duration NN cord-005646-xhx9pzhj 4276 11 of of IN cord-005646-xhx9pzhj 4276 12 t6 t6 NNP cord-005646-xhx9pzhj 4276 13 days day NNS cord-005646-xhx9pzhj 4276 14 ( ( -LRB- cord-005646-xhx9pzhj 4276 15 2,5 2,5 CD cord-005646-xhx9pzhj 4276 16 - - SYM cord-005646-xhx9pzhj 4276 17 164 164 CD cord-005646-xhx9pzhj 4276 18 ) ) -RRB- cord-005646-xhx9pzhj 4276 19 . . . cord-005646-xhx9pzhj 4277 1 Results result NNS cord-005646-xhx9pzhj 4277 2 : : : cord-005646-xhx9pzhj 4278 1 Patients patient NNS cord-005646-xhx9pzhj 4278 2 were be VBD cord-005646-xhx9pzhj 4278 3 discharged discharge VBN cord-005646-xhx9pzhj 4278 4 at at IN cord-005646-xhx9pzhj 4278 5 the the DT cord-005646-xhx9pzhj 4278 6 mean mean NN cord-005646-xhx9pzhj 4278 7 of of IN cord-005646-xhx9pzhj 4278 8 68 68 CD cord-005646-xhx9pzhj 4278 9 days day NNS cord-005646-xhx9pzhj 4278 10 following follow VBG cord-005646-xhx9pzhj 4278 11 birth birth NN cord-005646-xhx9pzhj 4278 12 ( ( -LRB- cord-005646-xhx9pzhj 4278 13 17 17 CD cord-005646-xhx9pzhj 4278 14 - - SYM cord-005646-xhx9pzhj 4278 15 260 260 CD cord-005646-xhx9pzhj 4278 16 ) ) -RRB- cord-005646-xhx9pzhj 4278 17 following follow VBG cord-005646-xhx9pzhj 4278 18 complete complete JJ cord-005646-xhx9pzhj 4278 19 epithelialization epithelialization NN cord-005646-xhx9pzhj 4278 20 of of IN cord-005646-xhx9pzhj 4278 21 the the DT cord-005646-xhx9pzhj 4278 22 omphalocele omphalocele NNP cord-005646-xhx9pzhj 4278 23 . . . cord-005646-xhx9pzhj 4279 1 Following follow VBG cord-005646-xhx9pzhj 4279 2 the the DT cord-005646-xhx9pzhj 4279 3 initial initial JJ cord-005646-xhx9pzhj 4279 4 stabilisation stabilisation NN cord-005646-xhx9pzhj 4279 5 period period NN cord-005646-xhx9pzhj 4279 6 parents parent NNS cord-005646-xhx9pzhj 4279 7 were be VBD cord-005646-xhx9pzhj 4279 8 involved involve VBN cord-005646-xhx9pzhj 4279 9 in in IN cord-005646-xhx9pzhj 4279 10 daily daily JJ cord-005646-xhx9pzhj 4279 11 care care NN cord-005646-xhx9pzhj 4279 12 of of IN cord-005646-xhx9pzhj 4279 13 all all DT cord-005646-xhx9pzhj 4279 14 patients patient NNS cord-005646-xhx9pzhj 4279 15 even even RB cord-005646-xhx9pzhj 4279 16 during during IN cord-005646-xhx9pzhj 4279 17 artificial artificial JJ cord-005646-xhx9pzhj 4279 18 ventialation ventialation NN cord-005646-xhx9pzhj 4279 19 . . . cord-005646-xhx9pzhj 4280 1 Enteral enteral NN cord-005646-xhx9pzhj 4280 2 intake intake NN cord-005646-xhx9pzhj 4280 3 was be VBD cord-005646-xhx9pzhj 4280 4 started start VBN cord-005646-xhx9pzhj 4280 5 at at IN cord-005646-xhx9pzhj 4280 6 a a DT cord-005646-xhx9pzhj 4280 7 median median NN cord-005646-xhx9pzhj 4280 8 of of IN cord-005646-xhx9pzhj 4280 9 2 2 CD cord-005646-xhx9pzhj 4280 10 days day NNS cord-005646-xhx9pzhj 4280 11 ( ( -LRB- cord-005646-xhx9pzhj 4280 12 1 1 CD cord-005646-xhx9pzhj 4280 13 - - SYM cord-005646-xhx9pzhj 4280 14 18 18 CD cord-005646-xhx9pzhj 4280 15 ) ) -RRB- cord-005646-xhx9pzhj 4280 16 . . . cord-005646-xhx9pzhj 4281 1 Colonization colonization NN cord-005646-xhx9pzhj 4281 2 of of IN cord-005646-xhx9pzhj 4281 3 the the DT cord-005646-xhx9pzhj 4281 4 omphalocele omphalocele NN cord-005646-xhx9pzhj 4281 5 was be VBD cord-005646-xhx9pzhj 4281 6 observed observe VBN cord-005646-xhx9pzhj 4281 7 within within IN cord-005646-xhx9pzhj 4281 8 2 2 CD cord-005646-xhx9pzhj 4281 9 -4 -4 CD cord-005646-xhx9pzhj 4281 10 days day NNS cord-005646-xhx9pzhj 4281 11 in in IN cord-005646-xhx9pzhj 4281 12 all all DT cord-005646-xhx9pzhj 4281 13 patients patient NNS cord-005646-xhx9pzhj 4281 14 . . . cord-005646-xhx9pzhj 4282 1 Although although IN cord-005646-xhx9pzhj 4282 2 infectious infectious JJ cord-005646-xhx9pzhj 4282 3 periods period NNS cord-005646-xhx9pzhj 4282 4 were be VBD cord-005646-xhx9pzhj 4282 5 observed observe VBN cord-005646-xhx9pzhj 4282 6 at at IN cord-005646-xhx9pzhj 4282 7 regular regular JJ cord-005646-xhx9pzhj 4282 8 intervals interval NNS cord-005646-xhx9pzhj 4282 9 , , , cord-005646-xhx9pzhj 4282 10 sepsis sepsis NN cord-005646-xhx9pzhj 4282 11 was be VBD cord-005646-xhx9pzhj 4282 12 the the DT cord-005646-xhx9pzhj 4282 13 primarily primarily JJ cord-005646-xhx9pzhj 4282 14 cause cause NN cord-005646-xhx9pzhj 4282 15 of of IN cord-005646-xhx9pzhj 4282 16 death death NN cord-005646-xhx9pzhj 4282 17 in in IN cord-005646-xhx9pzhj 4282 18 only only RB cord-005646-xhx9pzhj 4282 19 3 3 CD cord-005646-xhx9pzhj 4282 20 of of IN cord-005646-xhx9pzhj 4282 21 the the DT cord-005646-xhx9pzhj 4282 22 6 6 CD cord-005646-xhx9pzhj 4282 23 patients patient NNS cord-005646-xhx9pzhj 4282 24 who who WP cord-005646-xhx9pzhj 4282 25 died die VBD cord-005646-xhx9pzhj 4282 26 , , , cord-005646-xhx9pzhj 4283 1 In in IN cord-005646-xhx9pzhj 4283 2 conclusion conclusion NN cord-005646-xhx9pzhj 4283 3 : : : cord-005646-xhx9pzhj 4283 4 Nursing nursing NN cord-005646-xhx9pzhj 4283 5 care care NN cord-005646-xhx9pzhj 4283 6 to to TO cord-005646-xhx9pzhj 4283 7 prevent prevent VB cord-005646-xhx9pzhj 4283 8 sepsis sepsis NN cord-005646-xhx9pzhj 4283 9 in in IN cord-005646-xhx9pzhj 4283 10 patients patient NNS cord-005646-xhx9pzhj 4283 11 with with IN cord-005646-xhx9pzhj 4283 12 ( ( -LRB- cord-005646-xhx9pzhj 4283 13 giant giant NN cord-005646-xhx9pzhj 4283 14 ) ) -RRB- cord-005646-xhx9pzhj 4283 15 omphalocele omphalocele NNP cord-005646-xhx9pzhj 4283 16 is be VBZ cord-005646-xhx9pzhj 4283 17 feasible feasible JJ cord-005646-xhx9pzhj 4283 18 for for IN cord-005646-xhx9pzhj 4283 19 a a DT cord-005646-xhx9pzhj 4283 20 long long JJ cord-005646-xhx9pzhj 4283 21 period period NN cord-005646-xhx9pzhj 4283 22 of of IN cord-005646-xhx9pzhj 4283 23 time time NN cord-005646-xhx9pzhj 4283 24 and and CC cord-005646-xhx9pzhj 4283 25 can can MD cord-005646-xhx9pzhj 4283 26 be be VB cord-005646-xhx9pzhj 4283 27 performed perform VBN cord-005646-xhx9pzhj 4283 28 with with IN cord-005646-xhx9pzhj 4283 29 simple simple JJ cord-005646-xhx9pzhj 4283 30 measures measure NNS cord-005646-xhx9pzhj 4283 31 , , , cord-005646-xhx9pzhj 4283 32 Since since IN cord-005646-xhx9pzhj 4283 33 June June NNP cord-005646-xhx9pzhj 4283 34 1994 1994 CD cord-005646-xhx9pzhj 4283 35 , , , cord-005646-xhx9pzhj 4283 36 we -PRON- PRP cord-005646-xhx9pzhj 4283 37 have have VBP cord-005646-xhx9pzhj 4283 38 been be VBN cord-005646-xhx9pzhj 4283 39 using use VBG cord-005646-xhx9pzhj 4283 40 Nasal Nasal NNP cord-005646-xhx9pzhj 4283 41 CPAP cpap NN cord-005646-xhx9pzhj 4283 42 in in IN cord-005646-xhx9pzhj 4283 43 the the DT cord-005646-xhx9pzhj 4283 44 treatment treatment NN cord-005646-xhx9pzhj 4283 45 of of IN cord-005646-xhx9pzhj 4283 46 respiratory respiratory JJ cord-005646-xhx9pzhj 4283 47 disorders disorder NNS cord-005646-xhx9pzhj 4283 48 in in IN cord-005646-xhx9pzhj 4283 49 newborn newborn JJ cord-005646-xhx9pzhj 4283 50 infants infant NNS cord-005646-xhx9pzhj 4283 51 ( ( -LRB- cord-005646-xhx9pzhj 4283 52 Severe severe JJ cord-005646-xhx9pzhj 4283 53 Apnea apnea NN cord-005646-xhx9pzhj 4283 54 Syndrom Syndrom NNP cord-005646-xhx9pzhj 4283 55 , , , cord-005646-xhx9pzhj 4283 56 Tachypnea Tachypnea NNP cord-005646-xhx9pzhj 4283 57 , , , cord-005646-xhx9pzhj 4283 58 Hyaline hyaline JJ cord-005646-xhx9pzhj 4283 59 Membrane membrane NN cord-005646-xhx9pzhj 4283 60 Disease Disease NNP cord-005646-xhx9pzhj 4283 61 ) ) -RRB- cord-005646-xhx9pzhj 4283 62 . . . cord-005646-xhx9pzhj 4284 1 In in IN cord-005646-xhx9pzhj 4284 2 newborns newborn NNS cord-005646-xhx9pzhj 4284 3 presenting present VBG cord-005646-xhx9pzhj 4284 4 hyaline hyaline JJ cord-005646-xhx9pzhj 4284 5 membrane membrane NN cord-005646-xhx9pzhj 4284 6 disease disease NN cord-005646-xhx9pzhj 4284 7 , , , cord-005646-xhx9pzhj 4284 8 we -PRON- PRP cord-005646-xhx9pzhj 4284 9 have have VBP cord-005646-xhx9pzhj 4284 10 used use VBN cord-005646-xhx9pzhj 4284 11 CPAP CPAP NNP cord-005646-xhx9pzhj 4284 12 and and CC cord-005646-xhx9pzhj 4284 13 administered administer VBN cord-005646-xhx9pzhj 4284 14 surfactant surfactant NN cord-005646-xhx9pzhj 4284 15 therapy therapy NN cord-005646-xhx9pzhj 4284 16 to to IN cord-005646-xhx9pzhj 4284 17 25 25 CD cord-005646-xhx9pzhj 4284 18 premature premature JJ cord-005646-xhx9pzhj 4284 19 babies baby NNS cord-005646-xhx9pzhj 4284 20 out out IN cord-005646-xhx9pzhj 4284 21 of of IN cord-005646-xhx9pzhj 4284 22 70 70 CD cord-005646-xhx9pzhj 4284 23 . . . cord-005646-xhx9pzhj 4285 1 Clinical clinical JJ cord-005646-xhx9pzhj 4285 2 data datum NNS cord-005646-xhx9pzhj 4285 3 were be VBD cord-005646-xhx9pzhj 4285 4 : : : cord-005646-xhx9pzhj 4285 5 Mean mean JJ cord-005646-xhx9pzhj 4285 6 GA GA NNP cord-005646-xhx9pzhj 4285 7 : : : cord-005646-xhx9pzhj 4285 8 30.8 30.8 CD cord-005646-xhx9pzhj 4285 9 + + SYM cord-005646-xhx9pzhj 4285 10 23 23 CD cord-005646-xhx9pzhj 4285 11 weeks week NNS cord-005646-xhx9pzhj 4285 12 . . . cord-005646-xhx9pzhj 4286 1 Mean mean JJ cord-005646-xhx9pzhj 4286 2 BW BW NNP cord-005646-xhx9pzhj 4286 3 : : : cord-005646-xhx9pzhj 4286 4 1686 1686 CD cord-005646-xhx9pzhj 4286 5 + + SYM cord-005646-xhx9pzhj 4286 6 551 551 CD cord-005646-xhx9pzhj 4286 7 g. g. NN cord-005646-xhx9pzhj 4286 8 Mean mean JJ cord-005646-xhx9pzhj 4286 9 administration administration NN cord-005646-xhx9pzhj 4286 10 time time NN cord-005646-xhx9pzhj 4286 11 was be VBD cord-005646-xhx9pzhj 4286 12 11 11 CD cord-005646-xhx9pzhj 4286 13 hours hour NNS cord-005646-xhx9pzhj 4286 14 . . . cord-005646-xhx9pzhj 4287 1 Before before IN cord-005646-xhx9pzhj 4287 2 administration administration NN cord-005646-xhx9pzhj 4287 3 , , , cord-005646-xhx9pzhj 4287 4 mean mean JJ cord-005646-xhx9pzhj 4287 5 FiO2 FiO2 NNS cord-005646-xhx9pzhj 4287 6 was be VBD cord-005646-xhx9pzhj 4287 7 0.4 0.4 CD cord-005646-xhx9pzhj 4287 8 + + SYM cord-005646-xhx9pzhj 4287 9 0.07 0.07 CD cord-005646-xhx9pzhj 4287 10 , , , cord-005646-xhx9pzhj 4287 11 mean mean JJ cord-005646-xhx9pzhj 4287 12 PaO2 pao2 JJ cord-005646-xhx9pzhj 4287 13 6.2 6.2 CD cord-005646-xhx9pzhj 4287 14 + + SYM cord-005646-xhx9pzhj 4287 15 1.8 1.8 CD cord-005646-xhx9pzhj 4287 16 KPa KPa NNS cord-005646-xhx9pzhj 4288 1 and and CC cord-005646-xhx9pzhj 4288 2 mean mean VB cord-005646-xhx9pzhj 4288 3 a a DT cord-005646-xhx9pzhj 4288 4 / / SYM cord-005646-xhx9pzhj 4288 5 AO2 AO2 NNP cord-005646-xhx9pzhj 4288 6 ratio ratio NN cord-005646-xhx9pzhj 4288 7 0.21 0.21 CD cord-005646-xhx9pzhj 4288 8 . . . cord-005646-xhx9pzhj 4289 1 All all DT cord-005646-xhx9pzhj 4289 2 babies baby NNS cord-005646-xhx9pzhj 4289 3 were be VBD cord-005646-xhx9pzhj 4289 4 intubated intubate VBN cord-005646-xhx9pzhj 4289 5 for for IN cord-005646-xhx9pzhj 4289 6 administration administration NN cord-005646-xhx9pzhj 4289 7 of of IN cord-005646-xhx9pzhj 4289 8 surfactant surfactant NN cord-005646-xhx9pzhj 4289 9 ( ( -LRB- cord-005646-xhx9pzhj 4289 10 Curosurf Curosurf NNP cord-005646-xhx9pzhj 4289 11 ) ) -RRB- cord-005646-xhx9pzhj 4289 12 and and CC cord-005646-xhx9pzhj 4289 13 were be VBD cord-005646-xhx9pzhj 4289 14 extubated extubate VBN cord-005646-xhx9pzhj 4289 15 after after IN cord-005646-xhx9pzhj 4289 16 half half PDT cord-005646-xhx9pzhj 4289 17 an an DT cord-005646-xhx9pzhj 4289 18 hour hour NN cord-005646-xhx9pzhj 4289 19 to to IN cord-005646-xhx9pzhj 4289 20 3 3 CD cord-005646-xhx9pzhj 4289 21 hours hour NNS cord-005646-xhx9pzhj 4289 22 after after IN cord-005646-xhx9pzhj 4289 23 administration administration NN cord-005646-xhx9pzhj 4289 24 . . . cord-005646-xhx9pzhj 4290 1 This this DT cord-005646-xhx9pzhj 4290 2 treatment treatment NN cord-005646-xhx9pzhj 4290 3 failed fail VBD cord-005646-xhx9pzhj 4290 4 for for IN cord-005646-xhx9pzhj 4290 5 seven seven CD cord-005646-xhx9pzhj 4290 6 babies baby NNS cord-005646-xhx9pzhj 4290 7 and and CC cord-005646-xhx9pzhj 4290 8 they -PRON- PRP cord-005646-xhx9pzhj 4290 9 were be VBD cord-005646-xhx9pzhj 4290 10 ventilated ventilate VBN cord-005646-xhx9pzhj 4290 11 by by IN cord-005646-xhx9pzhj 4290 12 oscillation oscillation NN cord-005646-xhx9pzhj 4290 13 ventilation ventilation NN cord-005646-xhx9pzhj 4290 14 ; ; : cord-005646-xhx9pzhj 4290 15 all all DT cord-005646-xhx9pzhj 4290 16 babies baby NNS cord-005646-xhx9pzhj 4290 17 survived survive VBD cord-005646-xhx9pzhj 4290 18 . . . cord-005646-xhx9pzhj 4291 1 Complications complication NNS cord-005646-xhx9pzhj 4291 2 : : : cord-005646-xhx9pzhj 4291 3 we -PRON- PRP cord-005646-xhx9pzhj 4291 4 have have VBP cord-005646-xhx9pzhj 4291 5 observed observe VBN cord-005646-xhx9pzhj 4291 6 pneumothorax pneumothorax NN cord-005646-xhx9pzhj 4291 7 in in IN cord-005646-xhx9pzhj 4291 8 2 2 CD cord-005646-xhx9pzhj 4291 9 cases case NNS cord-005646-xhx9pzhj 4291 10 and and CC cord-005646-xhx9pzhj 4291 11 1 1 CD cord-005646-xhx9pzhj 4291 12 cerebral cerebral JJ cord-005646-xhx9pzhj 4291 13 hemorrage hemorrage NN cord-005646-xhx9pzhj 4291 14 . . . cord-005646-xhx9pzhj 4292 1 Mean mean JJ cord-005646-xhx9pzhj 4292 2 duration duration NN cord-005646-xhx9pzhj 4292 3 time time NN cord-005646-xhx9pzhj 4292 4 of of IN cord-005646-xhx9pzhj 4292 5 nasal nasal NN cord-005646-xhx9pzhj 4292 6 CPAP CPAP NNP cord-005646-xhx9pzhj 4292 7 was be VBD cord-005646-xhx9pzhj 4292 8 71 71 CD cord-005646-xhx9pzhj 4292 9 hours hour NNS cord-005646-xhx9pzhj 4292 10 for for IN cord-005646-xhx9pzhj 4292 11 the the DT cord-005646-xhx9pzhj 4292 12 18 18 CD cord-005646-xhx9pzhj 4292 13 babies baby NNS cord-005646-xhx9pzhj 4292 14 without without IN cord-005646-xhx9pzhj 4292 15 assisted assist VBN cord-005646-xhx9pzhj 4292 16 ventilation ventilation NN cord-005646-xhx9pzhj 4292 17 . . . cord-005646-xhx9pzhj 4293 1 Nurses nurse NNS cord-005646-xhx9pzhj 4293 2 in in IN cord-005646-xhx9pzhj 4293 3 charge charge NN cord-005646-xhx9pzhj 4293 4 of of IN cord-005646-xhx9pzhj 4293 5 babies baby NNS cord-005646-xhx9pzhj 4293 6 with with IN cord-005646-xhx9pzhj 4293 7 nasal nasal NN cord-005646-xhx9pzhj 4293 8 CPAP CPAP NNP cord-005646-xhx9pzhj 4293 9 should should MD cord-005646-xhx9pzhj 4293 10 be be VB cord-005646-xhx9pzhj 4293 11 aware aware JJ cord-005646-xhx9pzhj 4293 12 of of IN cord-005646-xhx9pzhj 4293 13 neonatal neonatal JJ cord-005646-xhx9pzhj 4293 14 care care NN cord-005646-xhx9pzhj 4293 15 , , , cord-005646-xhx9pzhj 4293 16 of of IN cord-005646-xhx9pzhj 4293 17 the the DT cord-005646-xhx9pzhj 4293 18 possibility possibility NN cord-005646-xhx9pzhj 4293 19 of of IN cord-005646-xhx9pzhj 4293 20 surfactant surfactant NN cord-005646-xhx9pzhj 4293 21 administration administration NN cord-005646-xhx9pzhj 4293 22 and and CC cord-005646-xhx9pzhj 4293 23 of of IN cord-005646-xhx9pzhj 4293 24 complications complication NNS cord-005646-xhx9pzhj 4293 25 during during IN cord-005646-xhx9pzhj 4293 26 this this DT cord-005646-xhx9pzhj 4293 27 type type NN cord-005646-xhx9pzhj 4293 28 of of IN cord-005646-xhx9pzhj 4293 29 treatment treatment NN cord-005646-xhx9pzhj 4293 30 . . . cord-005646-xhx9pzhj 4294 1 Therefore therefore RB cord-005646-xhx9pzhj 4294 2 nurses nurse NNS cord-005646-xhx9pzhj 4294 3 should should MD cord-005646-xhx9pzhj 4294 4 know know VB cord-005646-xhx9pzhj 4294 5 very very RB cord-005646-xhx9pzhj 4294 6 well well RB cord-005646-xhx9pzhj 4294 7 the the DT cord-005646-xhx9pzhj 4294 8 use use NN cord-005646-xhx9pzhj 4294 9 of of IN cord-005646-xhx9pzhj 4294 10 nasal nasal NN cord-005646-xhx9pzhj 4294 11 CPAP CPAP NNP cord-005646-xhx9pzhj 4294 12 , , , cord-005646-xhx9pzhj 4294 13 the the DT cord-005646-xhx9pzhj 4294 14 monitoring monitoring NN cord-005646-xhx9pzhj 4294 15 during during IN cord-005646-xhx9pzhj 4294 16 this this DT cord-005646-xhx9pzhj 4294 17 treatment treatment NN cord-005646-xhx9pzhj 4294 18 , , , cord-005646-xhx9pzhj 4294 19 the the DT cord-005646-xhx9pzhj 4294 20 fixation fixation NN cord-005646-xhx9pzhj 4294 21 of of IN cord-005646-xhx9pzhj 4294 22 the the DT cord-005646-xhx9pzhj 4294 23 system system NN cord-005646-xhx9pzhj 4294 24 on on IN cord-005646-xhx9pzhj 4294 25 the the DT cord-005646-xhx9pzhj 4294 26 baby baby NN cord-005646-xhx9pzhj 4294 27 , , , cord-005646-xhx9pzhj 4294 28 nursing nursing NN cord-005646-xhx9pzhj 4294 29 of of IN cord-005646-xhx9pzhj 4294 30 the the DT cord-005646-xhx9pzhj 4294 31 babies baby NNS cord-005646-xhx9pzhj 4294 32 during during IN cord-005646-xhx9pzhj 4294 33 this this DT cord-005646-xhx9pzhj 4294 34 treatment treatment NN cord-005646-xhx9pzhj 4294 35 and and CC cord-005646-xhx9pzhj 4294 36 finally finally RB cord-005646-xhx9pzhj 4294 37 should should MD cord-005646-xhx9pzhj 4294 38 take take VB cord-005646-xhx9pzhj 4294 39 care care NN cord-005646-xhx9pzhj 4294 40 of of IN cord-005646-xhx9pzhj 4294 41 the the DT cord-005646-xhx9pzhj 4294 42 baby baby NN cord-005646-xhx9pzhj 4294 43 physical physical JJ cord-005646-xhx9pzhj 4294 44 and and CC cord-005646-xhx9pzhj 4294 45 psychological psychological JJ cord-005646-xhx9pzhj 4294 46 well well NN cord-005646-xhx9pzhj 4294 47 being being NN cord-005646-xhx9pzhj 4294 48 . . . cord-005646-xhx9pzhj 4295 1 As as IN cord-005646-xhx9pzhj 4295 2 a a DT cord-005646-xhx9pzhj 4295 3 conclusion conclusion NN cord-005646-xhx9pzhj 4295 4 , , , cord-005646-xhx9pzhj 4295 5 nurses nurse NNS cord-005646-xhx9pzhj 4295 6 in in IN cord-005646-xhx9pzhj 4295 7 intensive intensive JJ cord-005646-xhx9pzhj 4295 8 care care NN cord-005646-xhx9pzhj 4295 9 neonatal neonatal JJ cord-005646-xhx9pzhj 4295 10 units unit NNS cord-005646-xhx9pzhj 4295 11 should should MD cord-005646-xhx9pzhj 4295 12 know know VB cord-005646-xhx9pzhj 4295 13 the the DT cord-005646-xhx9pzhj 4295 14 possibility possibility NN cord-005646-xhx9pzhj 4295 15 of of IN cord-005646-xhx9pzhj 4295 16 treatment treatment NN cord-005646-xhx9pzhj 4295 17 of of IN cord-005646-xhx9pzhj 4295 18 RDS RDS NNP cord-005646-xhx9pzhj 4295 19 by by IN cord-005646-xhx9pzhj 4295 20 nasal nasal NN cord-005646-xhx9pzhj 4295 21 CPAP cpap NN cord-005646-xhx9pzhj 4295 22 and and CC cord-005646-xhx9pzhj 4295 23 should should MD cord-005646-xhx9pzhj 4295 24 be be VB cord-005646-xhx9pzhj 4295 25 aware aware JJ cord-005646-xhx9pzhj 4295 26 of of IN cord-005646-xhx9pzhj 4295 27 baby baby NN cord-005646-xhx9pzhj 4295 28 - - HYPH cord-005646-xhx9pzhj 4295 29 nursing nursing NN cord-005646-xhx9pzhj 4295 30 . . . cord-005646-xhx9pzhj 4296 1 EMCO EMCO NNP cord-005646-xhx9pzhj 4296 2 in in IN cord-005646-xhx9pzhj 4296 3 the the DT cord-005646-xhx9pzhj 4296 4 postcardiotomy postcardiotomy NN cord-005646-xhx9pzhj 4296 5 infan_t infan_t '' cord-005646-xhx9pzhj 4296 6 : : : cord-005646-xhx9pzhj 4296 7 a a DT cord-005646-xhx9pzhj 4296 8 simplified simplified JJ cord-005646-xhx9pzhj 4296 9 circuit circuit NN cord-005646-xhx9pzhj 4296 10 and and CC cord-005646-xhx9pzhj 4296 11 reduced reduced JJ cord-005646-xhx9pzhj 4296 12 management management NN cord-005646-xhx9pzhj 4296 13 GRILLET GRILLET NNP cord-005646-xhx9pzhj 4296 14 lsabelle lsabelle NN cord-005646-xhx9pzhj 4296 15 , , , cord-005646-xhx9pzhj 4296 16 BOSSON BOSSON NNP cord-005646-xhx9pzhj 4296 17 Christa Christa NNP cord-005646-xhx9pzhj 4296 18 , , , cord-005646-xhx9pzhj 4296 19 GOELZ GOELZ NNP cord-005646-xhx9pzhj 4296 20 Andrea Andrea NNP cord-005646-xhx9pzhj 4296 21 , , , cord-005646-xhx9pzhj 4296 22 HELMER HELMER NNP cord-005646-xhx9pzhj 4296 23 Pascale Pascale NNP cord-005646-xhx9pzhj 4296 24 , , , cord-005646-xhx9pzhj 4296 25 ICU ICU NNP cord-005646-xhx9pzhj 4296 26 nurses nurse NNS cord-005646-xhx9pzhj 4296 27 , , , cord-005646-xhx9pzhj 4297 1 TSCHAUT TSCHAUT NNP cord-005646-xhx9pzhj 4297 2 Rudy Rudy NNP cord-005646-xhx9pzhj 4297 3 perfusianist perfusianist NN cord-005646-xhx9pzhj 4297 4 ALDO ALDO NNP cord-005646-xhx9pzhj 4297 5 CASTANEDA CASTANEDA NNP cord-005646-xhx9pzhj 4297 6 INSTITUTE INSTITUTE NNP cord-005646-xhx9pzhj 4297 7 , , , cord-005646-xhx9pzhj 4297 8 Clinique Clinique NNP cord-005646-xhx9pzhj 4297 9 de de NNP cord-005646-xhx9pzhj 4297 10 GENOLIER GENOLIER NNP cord-005646-xhx9pzhj 4297 11 , , , cord-005646-xhx9pzhj 4297 12 SUISSE SUISSE NNP cord-005646-xhx9pzhj 4298 1 To to TO cord-005646-xhx9pzhj 4298 2 improve improve VB cord-005646-xhx9pzhj 4298 3 postoperative postoperative JJ cord-005646-xhx9pzhj 4298 4 survival survival NN cord-005646-xhx9pzhj 4298 5 of of IN cord-005646-xhx9pzhj 4298 6 infants infant NNS cord-005646-xhx9pzhj 4298 7 with with IN cord-005646-xhx9pzhj 4298 8 repaired repair VBN cord-005646-xhx9pzhj 4298 9 cardiac cardiac JJ cord-005646-xhx9pzhj 4298 10 tessions tession NNS cord-005646-xhx9pzhj 4298 11 but but CC cord-005646-xhx9pzhj 4298 12 severe severe JJ cord-005646-xhx9pzhj 4298 13 residual residual JJ cord-005646-xhx9pzhj 4298 14 cardiopnlmonary cardiopnlmonary JJ cord-005646-xhx9pzhj 4298 15 dysfunction dysfunction NN cord-005646-xhx9pzhj 4298 16 , , , cord-005646-xhx9pzhj 4298 17 EMCO EMCO NNP cord-005646-xhx9pzhj 4298 18 was be VBD cord-005646-xhx9pzhj 4298 19 used use VBN cord-005646-xhx9pzhj 4298 20 in in IN cord-005646-xhx9pzhj 4298 21 4 4 CD cord-005646-xhx9pzhj 4298 22 infants infant NNS cord-005646-xhx9pzhj 4298 23 , , , cord-005646-xhx9pzhj 4298 24 ranging range VBG cord-005646-xhx9pzhj 4298 25 in in IN cord-005646-xhx9pzhj 4298 26 age age NN cord-005646-xhx9pzhj 4298 27 from from IN cord-005646-xhx9pzhj 4298 28 l0 l0 NNP cord-005646-xhx9pzhj 4298 29 days day NNS cord-005646-xhx9pzhj 4298 30 to to IN cord-005646-xhx9pzhj 4298 31 9 9 CD cord-005646-xhx9pzhj 4298 32 months month NNS cord-005646-xhx9pzhj 4298 33 and and CC cord-005646-xhx9pzhj 4298 34 in in IN cord-005646-xhx9pzhj 4298 35 weight weight NN cord-005646-xhx9pzhj 4298 36 from from IN cord-005646-xhx9pzhj 4298 37 2,8 2,8 CD cord-005646-xhx9pzhj 4298 38 kg kg NNS cord-005646-xhx9pzhj 4298 39 to to IN cord-005646-xhx9pzhj 4298 40 7,8 7,8 CD cord-005646-xhx9pzhj 4298 41 kg kg NN cord-005646-xhx9pzhj 4298 42 . . . cord-005646-xhx9pzhj 4299 1 Diagnosis diagnosis NN cord-005646-xhx9pzhj 4299 2 included include VBD cord-005646-xhx9pzhj 4299 3 TGA TGA NNP cord-005646-xhx9pzhj 4299 4 / / SYM cord-005646-xhx9pzhj 4299 5 intact intact JJ cord-005646-xhx9pzhj 4299 6 ventricular ventricular JJ cord-005646-xhx9pzhj 4299 7 septum septum NN cord-005646-xhx9pzhj 4299 8 ( ( -LRB- cord-005646-xhx9pzhj 4299 9 2 2 CD cord-005646-xhx9pzhj 4299 10 ) ) -RRB- cord-005646-xhx9pzhj 4300 1 ( ( -LRB- cord-005646-xhx9pzhj 4300 2 both both DT cord-005646-xhx9pzhj 4300 3 subiected subiecte VBN cord-005646-xhx9pzhj 4300 4 to to IN cord-005646-xhx9pzhj 4300 5 rapid rapid JJ cord-005646-xhx9pzhj 4300 6 arterial arterial JJ cord-005646-xhx9pzhj 4300 7 switch switch NN cord-005646-xhx9pzhj 4300 8 operation operation NN cord-005646-xhx9pzhj 4300 9 because because IN cord-005646-xhx9pzhj 4300 10 of of IN cord-005646-xhx9pzhj 4300 11 unsuitable unsuitable JJ cord-005646-xhx9pzhj 4300 12 LV LV NNP cord-005646-xhx9pzhj 4300 13 function function NN cord-005646-xhx9pzhj 4300 14 ) ) -RRB- cord-005646-xhx9pzhj 4300 15 and and CC cord-005646-xhx9pzhj 4300 16 TGA TGA NNP cord-005646-xhx9pzhj 4300 17 + + CC cord-005646-xhx9pzhj 4300 18 VSD VSD NNP cord-005646-xhx9pzhj 4300 19 ( ( -LRB- cord-005646-xhx9pzhj 4300 20 2 2 CD cord-005646-xhx9pzhj 4300 21 ) ) -RRB- cord-005646-xhx9pzhj 4300 22 . . . cord-005646-xhx9pzhj 4301 1 " " `` cord-005646-xhx9pzhj 4301 2 [ [ -LRB- cord-005646-xhx9pzhj 4301 3 ' ' '' cord-005646-xhx9pzhj 4301 4 he -PRON- PRP cord-005646-xhx9pzhj 4301 5 EMCO EMCO NNP cord-005646-xhx9pzhj 4301 6 circuit circuit NN cord-005646-xhx9pzhj 4301 7 included include VBD cord-005646-xhx9pzhj 4301 8 a a DT cord-005646-xhx9pzhj 4301 9 Sarns Sarns NNP cord-005646-xhx9pzhj 4301 10 roller roller NN cord-005646-xhx9pzhj 4301 11 15ump 15ump NN cord-005646-xhx9pzhj 4301 12 , , , cord-005646-xhx9pzhj 4301 13 a a DT cord-005646-xhx9pzhj 4301 14 Medtronic Medtronic NNP cord-005646-xhx9pzhj 4301 15 Minimax Minimax NNP cord-005646-xhx9pzhj 4301 16 plus plus CC cord-005646-xhx9pzhj 4301 17 Hollow hollow JJ cord-005646-xhx9pzhj 4301 18 fiber fiber NN cord-005646-xhx9pzhj 4301 19 oxygenator oxygenator NN cord-005646-xhx9pzhj 4301 20 and and CC cord-005646-xhx9pzhj 4301 21 tubing tubing NN cord-005646-xhx9pzhj 4301 22 ( ( -LRB- cord-005646-xhx9pzhj 4301 23 1/4 1/4 CD cord-005646-xhx9pzhj 4301 24 -1/16 -1/16 NN cord-005646-xhx9pzhj 4301 25 inch inch NN cord-005646-xhx9pzhj 4301 26 ) ) -RRB- cord-005646-xhx9pzhj 4301 27 with with IN cord-005646-xhx9pzhj 4301 28 bioactive bioactive JJ cord-005646-xhx9pzhj 4301 29 surfaces surface NNS cord-005646-xhx9pzhj 4301 30 , , , cord-005646-xhx9pzhj 4301 31 an an DT cord-005646-xhx9pzhj 4301 32 arterial arterial JJ cord-005646-xhx9pzhj 4301 33 canula canula NN cord-005646-xhx9pzhj 4301 34 10 10 CD cord-005646-xhx9pzhj 4301 35 Fr Fr NNP cord-005646-xhx9pzhj 4301 36 . . NNP cord-005646-xhx9pzhj 4301 37 , , , cord-005646-xhx9pzhj 4301 38 2 2 CD cord-005646-xhx9pzhj 4301 39 venous venous JJ cord-005646-xhx9pzhj 4301 40 canulas canulas NN cord-005646-xhx9pzhj 4301 41 : : : cord-005646-xhx9pzhj 4301 42 right right JJ cord-005646-xhx9pzhj 4301 43 atrial atrial JJ cord-005646-xhx9pzhj 4301 44 20 20 CD cord-005646-xhx9pzhj 4301 45 Fr Fr NNP cord-005646-xhx9pzhj 4301 46 , , , cord-005646-xhx9pzhj 4301 47 left leave VBD cord-005646-xhx9pzhj 4301 48 atrial atrial JJ cord-005646-xhx9pzhj 4301 49 12 12 CD cord-005646-xhx9pzhj 4301 50 Fr Fr NNP cord-005646-xhx9pzhj 4301 51 . . NNP cord-005646-xhx9pzhj 4301 52 , , , cord-005646-xhx9pzhj 4301 53 an an DT cord-005646-xhx9pzhj 4301 54 air air NN cord-005646-xhx9pzhj 4301 55 oxygen oxygen NN cord-005646-xhx9pzhj 4301 56 mixer mixer NN cord-005646-xhx9pzhj 4301 57 and and CC cord-005646-xhx9pzhj 4301 58 a a DT cord-005646-xhx9pzhj 4301 59 Sarns Sarns NNP cord-005646-xhx9pzhj 4301 60 heater heater NN cord-005646-xhx9pzhj 4301 61 . . . cord-005646-xhx9pzhj 4302 1 The the DT cord-005646-xhx9pzhj 4302 2 ACT ACT NNP cord-005646-xhx9pzhj 4302 3 was be VBD cord-005646-xhx9pzhj 4302 4 kept keep VBN cord-005646-xhx9pzhj 4302 5 between between IN cord-005646-xhx9pzhj 4302 6 180 180 CD cord-005646-xhx9pzhj 4302 7 - - SYM cord-005646-xhx9pzhj 4302 8 200 200 CD cord-005646-xhx9pzhj 4302 9 sec sec NNP cord-005646-xhx9pzhj 4302 10 . . . cord-005646-xhx9pzhj 4303 1 After after IN cord-005646-xhx9pzhj 4303 2 the the DT cord-005646-xhx9pzhj 4303 3 infant infant NN cord-005646-xhx9pzhj 4303 4 was be VBD cord-005646-xhx9pzhj 4303 5 connected connect VBN cord-005646-xhx9pzhj 4303 6 to to IN cord-005646-xhx9pzhj 4303 7 EMCO EMCO NNP cord-005646-xhx9pzhj 4303 8 by by IN cord-005646-xhx9pzhj 4303 9 the the DT cord-005646-xhx9pzhj 4303 10 surgical surgical JJ cord-005646-xhx9pzhj 4303 11 team team NN cord-005646-xhx9pzhj 4303 12 and and CC cord-005646-xhx9pzhj 4303 13 the the DT cord-005646-xhx9pzhj 4303 14 Perfusion Perfusion NNP cord-005646-xhx9pzhj 4303 15 Technologist Technologist NNP cord-005646-xhx9pzhj 4303 16 , , , cord-005646-xhx9pzhj 4303 17 the the DT cord-005646-xhx9pzhj 4303 18 patients patient NNS cord-005646-xhx9pzhj 4303 19 were be VBD cord-005646-xhx9pzhj 4303 20 being be VBG cord-005646-xhx9pzhj 4303 21 cared care VBN cord-005646-xhx9pzhj 4303 22 for for IN cord-005646-xhx9pzhj 4303 23 and and CC cord-005646-xhx9pzhj 4303 24 controlled control VBN cord-005646-xhx9pzhj 4303 25 exclusively exclusively RB cord-005646-xhx9pzhj 4303 26 by by IN cord-005646-xhx9pzhj 4303 27 the the DT cord-005646-xhx9pzhj 4303 28 1CU 1cu CD cord-005646-xhx9pzhj 4303 29 nurse nurse NN cord-005646-xhx9pzhj 4303 30 assigned assign VBN cord-005646-xhx9pzhj 4303 31 to to IN cord-005646-xhx9pzhj 4303 32 the the DT cord-005646-xhx9pzhj 4303 33 patient patient NN cord-005646-xhx9pzhj 4303 34 and and CC cord-005646-xhx9pzhj 4303 35 the the DT cord-005646-xhx9pzhj 4303 36 physician physician NN cord-005646-xhx9pzhj 4303 37 on on IN cord-005646-xhx9pzhj 4303 38 call call NN cord-005646-xhx9pzhj 4303 39 for for IN cord-005646-xhx9pzhj 4303 40 the the DT cord-005646-xhx9pzhj 4303 41 ICU ICU NNP cord-005646-xhx9pzhj 4303 42 , , , cord-005646-xhx9pzhj 4304 1 Pump pump NN cord-005646-xhx9pzhj 4304 2 flows flow NNS cord-005646-xhx9pzhj 4304 3 of of IN cord-005646-xhx9pzhj 4304 4 100 100 CD cord-005646-xhx9pzhj 4304 5 - - HYPH cord-005646-xhx9pzhj 4304 6 150ml 150ml NNP cord-005646-xhx9pzhj 4304 7 / / SYM cord-005646-xhx9pzhj 4304 8 kg kg NN cord-005646-xhx9pzhj 4304 9 / / SYM cord-005646-xhx9pzhj 4304 10 mln mln NNS cord-005646-xhx9pzhj 4304 11 were be VBD cord-005646-xhx9pzhj 4304 12 targeted target VBN cord-005646-xhx9pzhj 4304 13 to to TO cord-005646-xhx9pzhj 4304 14 insure insure VB cord-005646-xhx9pzhj 4304 15 an an DT cord-005646-xhx9pzhj 4304 16 adequate adequate JJ cord-005646-xhx9pzhj 4304 17 urine urine NN cord-005646-xhx9pzhj 4304 18 output output NN cord-005646-xhx9pzhj 4304 19 , , , cord-005646-xhx9pzhj 4304 20 a a DT cord-005646-xhx9pzhj 4304 21 brisk brisk JJ cord-005646-xhx9pzhj 4304 22 capillary capillary JJ cord-005646-xhx9pzhj 4304 23 fill fill NN cord-005646-xhx9pzhj 4304 24 and and CC cord-005646-xhx9pzhj 4304 25 physiologic physiologic JJ cord-005646-xhx9pzhj 4304 26 left left JJ cord-005646-xhx9pzhj 4304 27 and and CC cord-005646-xhx9pzhj 4304 28 right right JJ cord-005646-xhx9pzhj 4304 29 atrial atrial JJ cord-005646-xhx9pzhj 4304 30 pressures pressure NNS cord-005646-xhx9pzhj 4304 31 . . . cord-005646-xhx9pzhj 4305 1 Sodium sodium NN cord-005646-xhx9pzhj 4305 2 nitroprusside nitroprusside RB cord-005646-xhx9pzhj 4305 3 was be VBD cord-005646-xhx9pzhj 4305 4 used use VBN cord-005646-xhx9pzhj 4305 5 to to TO cord-005646-xhx9pzhj 4305 6 control control VB cord-005646-xhx9pzhj 4305 7 systemic systemic JJ cord-005646-xhx9pzhj 4305 8 hypertension hypertension NN cord-005646-xhx9pzhj 4305 9 while while IN cord-005646-xhx9pzhj 4305 10 all all DT cord-005646-xhx9pzhj 4305 11 other other JJ cord-005646-xhx9pzhj 4305 12 inotropic inotropic JJ cord-005646-xhx9pzhj 4305 13 drugs drug NNS cord-005646-xhx9pzhj 4305 14 were be VBD cord-005646-xhx9pzhj 4305 15 discontinued discontinue VBN cord-005646-xhx9pzhj 4305 16 . . . cord-005646-xhx9pzhj 4306 1 Inspired inspire VBN cord-005646-xhx9pzhj 4306 2 oxygen oxygen NN cord-005646-xhx9pzhj 4306 3 fraction fraction NN cord-005646-xhx9pzhj 4306 4 on on IN cord-005646-xhx9pzhj 4306 5 the the DT cord-005646-xhx9pzhj 4306 6 ventilator ventilator NN cord-005646-xhx9pzhj 4306 7 was be VBD cord-005646-xhx9pzhj 4306 8 reduced reduce VBN cord-005646-xhx9pzhj 4306 9 to to IN cord-005646-xhx9pzhj 4306 10 0,25 0,25 CD cord-005646-xhx9pzhj 4306 11 at at IN cord-005646-xhx9pzhj 4306 12 a a DT cord-005646-xhx9pzhj 4306 13 respiratory respiratory JJ cord-005646-xhx9pzhj 4306 14 rate rate NN cord-005646-xhx9pzhj 4306 15 of of IN cord-005646-xhx9pzhj 4306 16 10 10 CD cord-005646-xhx9pzhj 4306 17 - - SYM cord-005646-xhx9pzhj 4306 18 15 15 CD cord-005646-xhx9pzhj 4306 19 breaths breath NNS cord-005646-xhx9pzhj 4306 20 per per IN cord-005646-xhx9pzhj 4306 21 minute minute NN cord-005646-xhx9pzhj 4306 22 . . . cord-005646-xhx9pzhj 4307 1 Body body NN cord-005646-xhx9pzhj 4307 2 temperature temperature NN cord-005646-xhx9pzhj 4307 3 was be VBD cord-005646-xhx9pzhj 4307 4 maintened maintene VBN cord-005646-xhx9pzhj 4307 5 close close RB cord-005646-xhx9pzhj 4307 6 to to IN cord-005646-xhx9pzhj 4307 7 normal normal JJ cord-005646-xhx9pzhj 4307 8 . . . cord-005646-xhx9pzhj 4308 1 When when WRB cord-005646-xhx9pzhj 4308 2 the the DT cord-005646-xhx9pzhj 4308 3 heart heart NN cord-005646-xhx9pzhj 4308 4 started start VBD cord-005646-xhx9pzhj 4308 5 to to TO cord-005646-xhx9pzhj 4308 6 eject eject VB cord-005646-xhx9pzhj 4308 7 again again RB cord-005646-xhx9pzhj 4308 8 , , , cord-005646-xhx9pzhj 4308 9 inspired inspire VBN cord-005646-xhx9pzhj 4308 10 oxygen oxygen NN cord-005646-xhx9pzhj 4308 11 was be VBD cord-005646-xhx9pzhj 4308 12 increased increase VBN cord-005646-xhx9pzhj 4308 13 to to IN cord-005646-xhx9pzhj 4308 14 about about IN cord-005646-xhx9pzhj 4308 15 0,40 0,40 CD cord-005646-xhx9pzhj 4308 16 . . . cord-005646-xhx9pzhj 4309 1 The the DT cord-005646-xhx9pzhj 4309 2 preparation preparation NN cord-005646-xhx9pzhj 4309 3 for for IN cord-005646-xhx9pzhj 4309 4 weaning wean VBG cord-005646-xhx9pzhj 4309 5 from from IN cord-005646-xhx9pzhj 4309 6 EMCO EMCO NNP cord-005646-xhx9pzhj 4309 7 was be VBD cord-005646-xhx9pzhj 4309 8 done do VBN cord-005646-xhx9pzhj 4309 9 by by IN cord-005646-xhx9pzhj 4309 10 the the DT cord-005646-xhx9pzhj 4309 11 ICU ICU NNP cord-005646-xhx9pzhj 4309 12 nurse nurse NN cord-005646-xhx9pzhj 4309 13 : : : cord-005646-xhx9pzhj 4309 14 including include VBG cord-005646-xhx9pzhj 4309 15 oxygen oxygen NN cord-005646-xhx9pzhj 4309 16 fraction fraction NN cord-005646-xhx9pzhj 4309 17 and and CC cord-005646-xhx9pzhj 4309 18 ventilator ventilator NN cord-005646-xhx9pzhj 4309 19 rate rate NN cord-005646-xhx9pzhj 4309 20 . . . cord-005646-xhx9pzhj 4310 1 Weaning wean VBG cord-005646-xhx9pzhj 4310 2 from from IN cord-005646-xhx9pzhj 4310 3 EMCOwas emcowas NN cord-005646-xhx9pzhj 4310 4 coordinated coordinate VBN cord-005646-xhx9pzhj 4310 5 by by IN cord-005646-xhx9pzhj 4310 6 the the DT cord-005646-xhx9pzhj 4310 7 medical medical JJ cord-005646-xhx9pzhj 4310 8 / / SYM cord-005646-xhx9pzhj 4310 9 surgical surgical JJ cord-005646-xhx9pzhj 4310 10 team team NN cord-005646-xhx9pzhj 4310 11 and and CC cord-005646-xhx9pzhj 4310 12 the the DT cord-005646-xhx9pzhj 4310 13 Perfusion Perfusion NNP cord-005646-xhx9pzhj 4310 14 Technologist Technologist NNP cord-005646-xhx9pzhj 4310 15 . . . cord-005646-xhx9pzhj 4311 1 The the DT cord-005646-xhx9pzhj 4311 2 duration duration NN cord-005646-xhx9pzhj 4311 3 of of IN cord-005646-xhx9pzhj 4311 4 EMCO EMCO NNP cord-005646-xhx9pzhj 4311 5 in in IN cord-005646-xhx9pzhj 4311 6 the the DT cord-005646-xhx9pzhj 4311 7 4 4 CD cord-005646-xhx9pzhj 4311 8 patients patient NNS cord-005646-xhx9pzhj 4311 9 ranged range VBD cord-005646-xhx9pzhj 4311 10 from from IN cord-005646-xhx9pzhj 4311 11 2 2 CD cord-005646-xhx9pzhj 4311 12 to to TO cord-005646-xhx9pzhj 4311 13 9 9 CD cord-005646-xhx9pzhj 4311 14 days day NNS cord-005646-xhx9pzhj 4311 15 . . . cord-005646-xhx9pzhj 4312 1 Three three CD cord-005646-xhx9pzhj 4312 2 patients patient NNS cord-005646-xhx9pzhj 4312 3 ( ( -LRB- cord-005646-xhx9pzhj 4312 4 75 75 CD cord-005646-xhx9pzhj 4312 5 % % NN cord-005646-xhx9pzhj 4312 6 ) ) -RRB- cord-005646-xhx9pzhj 4312 7 were be VBD cord-005646-xhx9pzhj 4312 8 saccessflly saccessflly RB cord-005646-xhx9pzhj 4312 9 weaned wean VBN cord-005646-xhx9pzhj 4312 10 from from IN cord-005646-xhx9pzhj 4312 11 EMCO EMCO NNP cord-005646-xhx9pzhj 4312 12 . . . cord-005646-xhx9pzhj 4313 1 One one CD cord-005646-xhx9pzhj 4313 2 of of IN cord-005646-xhx9pzhj 4313 3 the the DT cord-005646-xhx9pzhj 4313 4 three three CD cord-005646-xhx9pzhj 4313 5 died die VBD cord-005646-xhx9pzhj 4313 6 within within IN cord-005646-xhx9pzhj 4313 7 24 24 CD cord-005646-xhx9pzhj 4313 8 hours hour NNS cord-005646-xhx9pzhj 4313 9 from from IN cord-005646-xhx9pzhj 4313 10 neurologic neurologic JJ cord-005646-xhx9pzhj 4313 11 complications complication NNS cord-005646-xhx9pzhj 4313 12 , , , cord-005646-xhx9pzhj 4313 13 unrelated unrelated JJ cord-005646-xhx9pzhj 4313 14 to to IN cord-005646-xhx9pzhj 4313 15 the the DT cord-005646-xhx9pzhj 4313 16 EMCO EMCO NNP cord-005646-xhx9pzhj 4313 17 . . . cord-005646-xhx9pzhj 4314 1 The the DT cord-005646-xhx9pzhj 4314 2 other other JJ cord-005646-xhx9pzhj 4314 3 2 2 CD cord-005646-xhx9pzhj 4314 4 patients patient NNS cord-005646-xhx9pzhj 4314 5 ( ( -LRB- cord-005646-xhx9pzhj 4314 6 both both DT cord-005646-xhx9pzhj 4314 7 with with IN cord-005646-xhx9pzhj 4314 8 TGA TGA NNP cord-005646-xhx9pzhj 4314 9 + + CC cord-005646-xhx9pzhj 4314 10 VSD VSD NNP cord-005646-xhx9pzhj 4314 11 ) ) -RRB- cord-005646-xhx9pzhj 4314 12 are be VBP cord-005646-xhx9pzhj 4314 13 long long JJ cord-005646-xhx9pzhj 4314 14 term term NN cord-005646-xhx9pzhj 4314 15 survivors survivor NNS cord-005646-xhx9pzhj 4314 16 and and CC cord-005646-xhx9pzhj 4314 17 are be VBP cord-005646-xhx9pzhj 4314 18 doing do VBG cord-005646-xhx9pzhj 4314 19 well well RB cord-005646-xhx9pzhj 4314 20 . . . cord-005646-xhx9pzhj 4315 1 Neither neither CC cord-005646-xhx9pzhj 4315 2 the the DT cord-005646-xhx9pzhj 4315 3 survivors survivor NNS cord-005646-xhx9pzhj 4315 4 nor nor CC cord-005646-xhx9pzhj 4315 5 the the DT cord-005646-xhx9pzhj 4315 6 patients patient NNS cord-005646-xhx9pzhj 4315 7 who who WP cord-005646-xhx9pzhj 4315 8 died die VBD cord-005646-xhx9pzhj 4315 9 bad bad JJ cord-005646-xhx9pzhj 4315 10 hemorrhagic hemorrhagic JJ cord-005646-xhx9pzhj 4315 11 complications complication NNS cord-005646-xhx9pzhj 4315 12 , , , cord-005646-xhx9pzhj 4315 13 despite despite IN cord-005646-xhx9pzhj 4315 14 the the DT cord-005646-xhx9pzhj 4315 15 fact fact NN cord-005646-xhx9pzhj 4315 16 that that IN cord-005646-xhx9pzhj 4315 17 3 3 CD cord-005646-xhx9pzhj 4315 18 of of IN cord-005646-xhx9pzhj 4315 19 the the DT cord-005646-xhx9pzhj 4315 20 4 4 CD cord-005646-xhx9pzhj 4315 21 were be VBD cord-005646-xhx9pzhj 4315 22 placed place VBN cord-005646-xhx9pzhj 4315 23 on on IN cord-005646-xhx9pzhj 4315 24 EMCO EMCO NNP cord-005646-xhx9pzhj 4315 25 because because IN cord-005646-xhx9pzhj 4315 26 of of IN cord-005646-xhx9pzhj 4315 27 failure failure NN cord-005646-xhx9pzhj 4315 28 to to TO cord-005646-xhx9pzhj 4315 29 wean wean VB cord-005646-xhx9pzhj 4315 30 from from IN cord-005646-xhx9pzhj 4315 31 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 4315 32 bypass bypass NN cord-005646-xhx9pzhj 4315 33 . . . cord-005646-xhx9pzhj 4316 1 The the DT cord-005646-xhx9pzhj 4316 2 simplified simplified JJ cord-005646-xhx9pzhj 4316 3 EMCO EMCO NNP cord-005646-xhx9pzhj 4316 4 circuit circuit NN cord-005646-xhx9pzhj 4316 5 worked work VBD cord-005646-xhx9pzhj 4316 6 reliably reliably RB cord-005646-xhx9pzhj 4316 7 throughout throughout IN cord-005646-xhx9pzhj 4316 8 this this DT cord-005646-xhx9pzhj 4316 9 experience experience NN cord-005646-xhx9pzhj 4316 10 and and CC cord-005646-xhx9pzhj 4316 11 no no DT cord-005646-xhx9pzhj 4316 12 complications complication NNS cord-005646-xhx9pzhj 4316 13 occurred occur VBD cord-005646-xhx9pzhj 4316 14 nor nor CC cord-005646-xhx9pzhj 4316 15 could could MD cord-005646-xhx9pzhj 4316 16 any any DT cord-005646-xhx9pzhj 4316 17 shortcoming shortcoming NN cord-005646-xhx9pzhj 4316 18 be be VB cord-005646-xhx9pzhj 4316 19 ascribed ascribe VBN cord-005646-xhx9pzhj 4316 20 to to IN cord-005646-xhx9pzhj 4316 21 the the DT cord-005646-xhx9pzhj 4316 22 use use NN cord-005646-xhx9pzhj 4316 23 of of IN cord-005646-xhx9pzhj 4316 24 this this DT cord-005646-xhx9pzhj 4316 25 reduced reduce VBN cord-005646-xhx9pzhj 4316 26 , , , cord-005646-xhx9pzhj 4316 27 cost cost VBD cord-005646-xhx9pzhj 4316 28 effective effective JJ cord-005646-xhx9pzhj 4316 29 management management NN cord-005646-xhx9pzhj 4316 30 team team NN cord-005646-xhx9pzhj 4316 31 . . . cord-005646-xhx9pzhj 4317 1 10 10 CD cord-005646-xhx9pzhj 4317 2 YEARS year NNS cord-005646-xhx9pzhj 4317 3 OF of IN cord-005646-xhx9pzhj 4317 4 PRACIICAL PRACIICAL NNP cord-005646-xhx9pzhj 4317 5 EXPERIENCE experience VBP cord-005646-xhx9pzhj 4317 6 WIIH WIIH NNP cord-005646-xhx9pzhj 4317 7 EXIRACORPOREAL EXIRACORPOREAL NNS cord-005646-xhx9pzhj 4317 8 MEMBRANE MEMBRANE VBZ cord-005646-xhx9pzhj 4317 9 OXYGENATION oxygenation NN cord-005646-xhx9pzhj 4317 10 ( ( -LRB- cord-005646-xhx9pzhj 4317 11 ECHO echo NN cord-005646-xhx9pzhj 4317 12 ) ) -RRB- cord-005646-xhx9pzhj 4317 13 -THE -THE . cord-005646-xhx9pzhj 4317 14 VIEWPOINT viewpoint NN cord-005646-xhx9pzhj 4317 15 OF of IN cord-005646-xhx9pzhj 4317 16 THE the DT cord-005646-xhx9pzhj 4317 17 NURSING nursing NN cord-005646-xhx9pzhj 4317 18 SIAEF SIAEF NNP cord-005646-xhx9pzhj 4317 19 Monika Monika NNP cord-005646-xhx9pzhj 4317 20 Schindler Schindler NNP cord-005646-xhx9pzhj 4317 21 in in IN cord-005646-xhx9pzhj 4317 22 1985 1985 CD cord-005646-xhx9pzhj 4318 1 a a DT cord-005646-xhx9pzhj 4318 2 training training NN cord-005646-xhx9pzhj 4318 3 program program NN cord-005646-xhx9pzhj 4318 4 was be VBD cord-005646-xhx9pzhj 4318 5 started start VBN cord-005646-xhx9pzhj 4318 6 for for IN cord-005646-xhx9pzhj 4318 7 the the DT cord-005646-xhx9pzhj 4318 8 introduction introduction NN cord-005646-xhx9pzhj 4318 9 of of IN cord-005646-xhx9pzhj 4318 10 ECHO echo NN cord-005646-xhx9pzhj 4318 11 in in IN cord-005646-xhx9pzhj 4318 12 the the DT cord-005646-xhx9pzhj 4318 13 Kinderklinik Kinderklinik NNP cord-005646-xhx9pzhj 4318 14 of of IN cord-005646-xhx9pzhj 4318 15 Mannheim Mannheim NNP cord-005646-xhx9pzhj 4318 16 / / SYM cord-005646-xhx9pzhj 4318 17 Germsny Germsny NNP cord-005646-xhx9pzhj 4318 18 . . . cord-005646-xhx9pzhj 4319 1 2 2 CD cord-005646-xhx9pzhj 4319 2 years year NNS cord-005646-xhx9pzhj 4319 3 later later RB cord-005646-xhx9pzhj 4319 4 ( ( -LRB- cord-005646-xhx9pzhj 4319 5 1987 1987 CD cord-005646-xhx9pzhj 4319 6 ) ) -RRB- cord-005646-xhx9pzhj 4320 1 the the DT cord-005646-xhx9pzhj 4320 2 first first JJ cord-005646-xhx9pzhj 4320 3 European european JJ cord-005646-xhx9pzhj 4320 4 ECHO echo NN cord-005646-xhx9pzhj 4320 5 patient patient NN cord-005646-xhx9pzhj 4320 6 , , , cord-005646-xhx9pzhj 4320 7 a a DT cord-005646-xhx9pzhj 4320 8 3 3 CD cord-005646-xhx9pzhj 4320 9 days day NNS cord-005646-xhx9pzhj 4320 10 old old JJ cord-005646-xhx9pzhj 4320 11 newborn newborn JJ cord-005646-xhx9pzhj 4320 12 baby baby NN cord-005646-xhx9pzhj 4320 13 , , , cord-005646-xhx9pzhj 4320 14 ~as ~as NNP cord-005646-xhx9pzhj 4320 15 treated treat VBN cord-005646-xhx9pzhj 4320 16 successfully successfully RB cord-005646-xhx9pzhj 4320 17 in in IN cord-005646-xhx9pzhj 4320 18 our -PRON- PRP$ cord-005646-xhx9pzhj 4320 19 institution institution NN cord-005646-xhx9pzhj 4320 20 . . . cord-005646-xhx9pzhj 4321 1 With with IN cord-005646-xhx9pzhj 4321 2 ECHO ECHO NNP cord-005646-xhx9pzhj 4321 3 , , , cord-005646-xhx9pzhj 4321 4 more more JJR cord-005646-xhx9pzhj 4321 5 treatment treatment NN cord-005646-xhx9pzhj 4321 6 modalities modality NNS cord-005646-xhx9pzhj 4322 1 ~ere ~ere NNP cord-005646-xhx9pzhj 4322 2 available available JJ cord-005646-xhx9pzhj 4322 3 after after IN cord-005646-xhx9pzhj 4322 4 failure failure NN cord-005646-xhx9pzhj 4322 5 of of IN cord-005646-xhx9pzhj 4322 6 conventional conventional JJ cord-005646-xhx9pzhj 4322 7 therapy therapy NN cord-005646-xhx9pzhj 4322 8 in in IN cord-005646-xhx9pzhj 4322 9 eases ease NNS cord-005646-xhx9pzhj 4322 10 of of IN cord-005646-xhx9pzhj 4322 11 severe severe JJ cord-005646-xhx9pzhj 4322 12 lung lung NN cord-005646-xhx9pzhj 4322 13 diseases disease NNS cord-005646-xhx9pzhj 4322 14 like like IN cord-005646-xhx9pzhj 4322 15 meeonium meeonium NNP cord-005646-xhx9pzhj 4322 16 aspiration aspiration NNP cord-005646-xhx9pzhj 4322 17 syndrome syndrome NN cord-005646-xhx9pzhj 4322 18 , , , cord-005646-xhx9pzhj 4322 19 congenital congenital JJ cord-005646-xhx9pzhj 4322 20 diaphragmatic diaphragmatic JJ cord-005646-xhx9pzhj 4322 21 hernia hernia NN cord-005646-xhx9pzhj 4322 22 , , , cord-005646-xhx9pzhj 4323 1 sepsis sepsis NN cord-005646-xhx9pzhj 4323 2 / / SYM cord-005646-xhx9pzhj 4323 3 pneumonia pneumonia NN cord-005646-xhx9pzhj 4323 4 , , , cord-005646-xhx9pzhj 4323 5 primary primary JJ cord-005646-xhx9pzhj 4323 6 persistent persistent JJ cord-005646-xhx9pzhj 4323 7 pulmonary pulmonary JJ cord-005646-xhx9pzhj 4323 8 hypertension hypertension NN cord-005646-xhx9pzhj 4323 9 of of IN cord-005646-xhx9pzhj 4323 10 the the DT cord-005646-xhx9pzhj 4323 11 newborn newborn JJ cord-005646-xhx9pzhj 4323 12 and and CC cord-005646-xhx9pzhj 4323 13 -in -in IN cord-005646-xhx9pzhj 4323 14 infants infant NNS cord-005646-xhx9pzhj 4323 15 and and CC cord-005646-xhx9pzhj 4323 16 children child NNS cord-005646-xhx9pzhj 4323 17 -ARDS -ARDS . cord-005646-xhx9pzhj 4324 1 ( ( -LRB- cord-005646-xhx9pzhj 4324 2 acquired acquire VBN cord-005646-xhx9pzhj 4324 3 respiratory respiratory JJ cord-005646-xhx9pzhj 4324 4 distress distress NN cord-005646-xhx9pzhj 4324 5 syndrome syndrome NN cord-005646-xhx9pzhj 4324 6 ) ) -RRB- cord-005646-xhx9pzhj 4324 7 due due IN cord-005646-xhx9pzhj 4324 8 to to IN cord-005646-xhx9pzhj 4324 9 multiple multiple JJ cord-005646-xhx9pzhj 4324 10 underlying underlie VBG cord-005646-xhx9pzhj 4324 11 illnesses illness NNS cord-005646-xhx9pzhj 4324 12 . . . cord-005646-xhx9pzhj 4325 1 In in IN cord-005646-xhx9pzhj 4325 2 1989 1989 CD cord-005646-xhx9pzhj 4325 3 the the DT cord-005646-xhx9pzhj 4325 4 first first JJ cord-005646-xhx9pzhj 4325 5 ARDS ARDS NNP cord-005646-xhx9pzhj 4325 6 patient patient NN cord-005646-xhx9pzhj 4325 7 , , , cord-005646-xhx9pzhj 4325 8 a a DT cord-005646-xhx9pzhj 4325 9 5 5 CD cord-005646-xhx9pzhj 4325 10 years year NNS cord-005646-xhx9pzhj 4325 11 old old JJ cord-005646-xhx9pzhj 4325 12 girl girl NN cord-005646-xhx9pzhj 4325 13 , , , cord-005646-xhx9pzhj 4325 14 was be VBD cord-005646-xhx9pzhj 4325 15 treated treat VBN cord-005646-xhx9pzhj 4325 16 successfully successfully RB cord-005646-xhx9pzhj 4326 1 ~ith ~ith NNP cord-005646-xhx9pzhj 4326 2 ECMO ECMO NNP cord-005646-xhx9pzhj 4326 3 in in IN cord-005646-xhx9pzhj 4326 4 Mannheim Mannheim NNP cord-005646-xhx9pzhj 4326 5 . . . cord-005646-xhx9pzhj 4327 1 Until until IN cord-005646-xhx9pzhj 4327 2 now now RB cord-005646-xhx9pzhj 4327 3 137 137 CD cord-005646-xhx9pzhj 4327 4 patients patient NNS cord-005646-xhx9pzhj 4327 5 ( ( -LRB- cord-005646-xhx9pzhj 4327 6 age age NN cord-005646-xhx9pzhj 4327 7 : : : cord-005646-xhx9pzhj 4327 8 I -PRON- PRP cord-005646-xhx9pzhj 4327 9 day day NN cord-005646-xhx9pzhj 4327 10 -10 -10 NN cord-005646-xhx9pzhj 4327 11 years year NNS cord-005646-xhx9pzhj 4327 12 ) ) -RRB- cord-005646-xhx9pzhj 4327 13 were be VBD cord-005646-xhx9pzhj 4327 14 treated treat VBN cord-005646-xhx9pzhj 4327 15 with with IN cord-005646-xhx9pzhj 4327 16 ECHO ECHO NNS cord-005646-xhx9pzhj 4327 17 in in IN cord-005646-xhx9pzhj 4327 18 our -PRON- PRP$ cord-005646-xhx9pzhj 4327 19 institution institution NN cord-005646-xhx9pzhj 4327 20 ; ; : cord-005646-xhx9pzhj 4327 21 111 111 CD cord-005646-xhx9pzhj 4327 22 additional additional JJ cord-005646-xhx9pzhj 4327 23 patients patient NNS cord-005646-xhx9pzhj 4327 24 were be VBD cord-005646-xhx9pzhj 4327 25 transferred transfer VBN cord-005646-xhx9pzhj 4327 26 to to IN cord-005646-xhx9pzhj 4327 27 us -PRON- PRP cord-005646-xhx9pzhj 4327 28 from from IN cord-005646-xhx9pzhj 4327 29 other other JJ cord-005646-xhx9pzhj 4327 30 institutions institution NNS cord-005646-xhx9pzhj 4327 31 for for IN cord-005646-xhx9pzhj 4327 32 therapy therapy NN cord-005646-xhx9pzhj 4327 33 with with IN cord-005646-xhx9pzhj 4327 34 ECHO ECHO NNP cord-005646-xhx9pzhj 4327 35 , , , cord-005646-xhx9pzhj 4327 36 but but CC cord-005646-xhx9pzhj 4327 37 could could MD cord-005646-xhx9pzhj 4327 38 be be VB cord-005646-xhx9pzhj 4327 39 treated treat VBN cord-005646-xhx9pzhj 4327 40 ~iEh ~iEh NNP cord-005646-xhx9pzhj 4327 41 alternative alternative JJ cord-005646-xhx9pzhj 4327 42 moda]ities moda]itie NNS cord-005646-xhx9pzhj 4327 43 of of IN cord-005646-xhx9pzhj 4327 44 therapy therapy NN cord-005646-xhx9pzhj 4327 45 like like IN cord-005646-xhx9pzhj 4327 46 improved improve VBN cord-005646-xhx9pzhj 4327 47 conventional conventional JJ cord-005646-xhx9pzhj 4327 48 ventilatory ventilatory JJ cord-005646-xhx9pzhj 4327 49 support support NN cord-005646-xhx9pzhj 4327 50 , , , cord-005646-xhx9pzhj 4327 51 high high JJ cord-005646-xhx9pzhj 4327 52 frequency frequency NN cord-005646-xhx9pzhj 4327 53 oscillatory oscillatory JJ cord-005646-xhx9pzhj 4327 54 ventilation ventilation NN cord-005646-xhx9pzhj 4327 55 ( ( -LRB- cord-005646-xhx9pzhj 4327 56 HFOV HFOV NNP cord-005646-xhx9pzhj 4327 57 ) ) -RRB- cord-005646-xhx9pzhj 4327 58 and and CC cord-005646-xhx9pzhj 4327 59 inhaled inhale VBN cord-005646-xhx9pzhj 4327 60 niEric niEric NNP cord-005646-xhx9pzhj 4327 61 oxide oxide NN cord-005646-xhx9pzhj 4327 62 ( ( -LRB- cord-005646-xhx9pzhj 4327 63 NO no UH cord-005646-xhx9pzhj 4327 64 ) ) -RRB- cord-005646-xhx9pzhj 4327 65 , , , cord-005646-xhx9pzhj 4327 66 Unexpectedly unexpectedly RB cord-005646-xhx9pzhj 4327 67 the the DT cord-005646-xhx9pzhj 4327 68 more more RBR cord-005646-xhx9pzhj 4327 69 ~ide ~ide JJ cord-005646-xhx9pzhj 4327 70 - - HYPH cord-005646-xhx9pzhj 4327 71 spread spread VBN cord-005646-xhx9pzhj 4327 72 use use NN cord-005646-xhx9pzhj 4327 73 of of IN cord-005646-xhx9pzhj 4327 74 HFOV HFOV NNP cord-005646-xhx9pzhj 4327 75 and and CC cord-005646-xhx9pzhj 4327 76 NO no DT cord-005646-xhx9pzhj 4327 77 -also -also NN cord-005646-xhx9pzhj 4328 1 in in IN cord-005646-xhx9pzhj 4328 2 other other JJ cord-005646-xhx9pzhj 4328 3 ~ntensive ~ntensive NNP cord-005646-xhx9pzhj 4328 4 care care NN cord-005646-xhx9pzhj 4328 5 units unit NNS cord-005646-xhx9pzhj 4328 6 -did -did : cord-005646-xhx9pzhj 4328 7 not not RB cord-005646-xhx9pzhj 4328 8 lead lead VBP cord-005646-xhx9pzhj 4328 9 to to IN cord-005646-xhx9pzhj 4328 10 a a DT cord-005646-xhx9pzhj 4328 11 reduction reduction NN cord-005646-xhx9pzhj 4328 12 of of IN cord-005646-xhx9pzhj 4328 13 the the DT cord-005646-xhx9pzhj 4328 14 ECHO echo NN cord-005646-xhx9pzhj 4328 15 frequency frequency NN cord-005646-xhx9pzhj 4328 16 in in IN cord-005646-xhx9pzhj 4328 17 our -PRON- PRP$ cord-005646-xhx9pzhj 4328 18 hospital hospital NN cord-005646-xhx9pzhj 4328 19 . . . cord-005646-xhx9pzhj 4329 1 Due due IN cord-005646-xhx9pzhj 4329 2 to to IN cord-005646-xhx9pzhj 4329 3 this this DT cord-005646-xhx9pzhj 4329 4 long long JJ cord-005646-xhx9pzhj 4329 5 ECMO ecmo NN cord-005646-xhx9pzhj 4329 6 practice practice NN cord-005646-xhx9pzhj 4329 7 , , , cord-005646-xhx9pzhj 4329 8 which which WDT cord-005646-xhx9pzhj 4329 9 is be VBZ cord-005646-xhx9pzhj 4329 10 helpful helpful JJ cord-005646-xhx9pzhj 4329 11 in in IN cord-005646-xhx9pzhj 4329 12 many many JJ cord-005646-xhx9pzhj 4329 13 critical critical JJ cord-005646-xhx9pzhj 4329 14 situations situation NNS cord-005646-xhx9pzhj 4329 15 , , , cord-005646-xhx9pzhj 4329 16 a a DT cord-005646-xhx9pzhj 4329 17 certain certain JJ cord-005646-xhx9pzhj 4329 18 routine routine NN cord-005646-xhx9pzhj 4329 19 came come VBD cord-005646-xhx9pzhj 4329 20 up up RP cord-005646-xhx9pzhj 4329 21 in in IN cord-005646-xhx9pzhj 4329 22 the the DT cord-005646-xhx9pzhj 4329 23 nursing nursing NN cord-005646-xhx9pzhj 4329 24 staff staff NN cord-005646-xhx9pzhj 4329 25 oF of IN cord-005646-xhx9pzhj 4329 26 our -PRON- PRP$ cord-005646-xhx9pzhj 4329 27 intensive intensive JJ cord-005646-xhx9pzhj 4329 28 care care NN cord-005646-xhx9pzhj 4329 29 units unit NNS cord-005646-xhx9pzhj 4329 30 ; ; : cord-005646-xhx9pzhj 4329 31 but but CC cord-005646-xhx9pzhj 4329 32 ECMO ECMO NNP cord-005646-xhx9pzhj 4329 33 continues continue VBZ cord-005646-xhx9pzhj 4329 34 to to TO cord-005646-xhx9pzhj 4329 35 be be VB cord-005646-xhx9pzhj 4329 36 a a DT cord-005646-xhx9pzhj 4329 37 maximum maximum JJ cord-005646-xhx9pzhj 4329 38 strain strain NN cord-005646-xhx9pzhj 4329 39 for for IN cord-005646-xhx9pzhj 4329 40 all all DT cord-005646-xhx9pzhj 4329 41 co co NNS cord-005646-xhx9pzhj 4329 42 - - NNS cord-005646-xhx9pzhj 4329 43 workers worker NNS cord-005646-xhx9pzhj 4329 44 and and CC cord-005646-xhx9pzhj 4329 45 implies imply VBZ cord-005646-xhx9pzhj 4329 46 an an DT cord-005646-xhx9pzhj 4329 47 high high JJ cord-005646-xhx9pzhj 4329 48 personnel personnel NNS cord-005646-xhx9pzhj 4329 49 and and CC cord-005646-xhx9pzhj 4329 50 material material NN cord-005646-xhx9pzhj 4329 51 / / SYM cord-005646-xhx9pzhj 4329 52 financial financial JJ cord-005646-xhx9pzhj 4329 53 - - HYPH cord-005646-xhx9pzhj 4329 54 expense expense NN cord-005646-xhx9pzhj 4329 55 . . . cord-005646-xhx9pzhj 4330 1 But but CC cord-005646-xhx9pzhj 4330 2 in in IN cord-005646-xhx9pzhj 4330 3 our -PRON- PRP$ cord-005646-xhx9pzhj 4330 4 opinion opinion NN cord-005646-xhx9pzhj 4330 5 the the DT cord-005646-xhx9pzhj 4330 6 improved improve VBN cord-005646-xhx9pzhj 4330 7 survival survival NN cord-005646-xhx9pzhj 4330 8 rates rate NNS cord-005646-xhx9pzhj 4330 9 in in IN cord-005646-xhx9pzhj 4330 10 severe severe JJ cord-005646-xhx9pzhj 4330 11 respiratory respiratory JJ cord-005646-xhx9pzhj 4330 12 failure-(70 failure-(70 NN cord-005646-xhx9pzhj 4330 13 % % NN cord-005646-xhx9pzhj 4330 14 in in IN cord-005646-xhx9pzhj 4330 15 neonates neonate NNS cord-005646-xhx9pzhj 4330 16 and and CC cord-005646-xhx9pzhj 4330 17 50 50 CD cord-005646-xhx9pzhj 4330 18 % % NN cord-005646-xhx9pzhj 4330 19 in in IN cord-005646-xhx9pzhj 4330 20 infants infant NNS cord-005646-xhx9pzhj 4330 21 and and CC cord-005646-xhx9pzhj 4330 22 children child NNS cord-005646-xhx9pzhj 4330 23 , , , cord-005646-xhx9pzhj 4330 24 estimated estimate VBN cord-005646-xhx9pzhj 4330 25 survival survival NN cord-005646-xhx9pzhj 4330 26 rates rate NNS cord-005646-xhx9pzhj 4330 27 under under IN cord-005646-xhx9pzhj 4330 28 continued continue VBN cord-005646-xhx9pzhj 4330 29 conventional conventional JJ cord-005646-xhx9pzhj 4330 30 management management NN cord-005646-xhx9pzhj 4330 31 : : : cord-005646-xhx9pzhj 4330 32 < < XX cord-005646-xhx9pzhj 4330 33 20 20 CD cord-005646-xhx9pzhj 4330 34 % % NN cord-005646-xhx9pzhj 4330 35 ) ) -RRB- cord-005646-xhx9pzhj 4330 36 by by IN cord-005646-xhx9pzhj 4330 37 the the DT cord-005646-xhx9pzhj 4330 38 use use NN cord-005646-xhx9pzhj 4330 39 of of IN cord-005646-xhx9pzhj 4330 40 ECHO ECHO NNP cord-005646-xhx9pzhj 4330 41 justifies justify VBZ cord-005646-xhx9pzhj 4330 42 this this DT cord-005646-xhx9pzhj 4330 43 expense expense NN cord-005646-xhx9pzhj 4330 44 , , , cord-005646-xhx9pzhj 4330 45 even even RB cord-005646-xhx9pzhj 4330 46 in in IN cord-005646-xhx9pzhj 4330 47 times time NNS cord-005646-xhx9pzhj 4330 48 of of IN cord-005646-xhx9pzhj 4330 49 less less JJR cord-005646-xhx9pzhj 4330 50 financial financial JJ cord-005646-xhx9pzhj 4330 51 support support NN cord-005646-xhx9pzhj 4330 52 for for IN cord-005646-xhx9pzhj 4330 53 public public JJ cord-005646-xhx9pzhj 4330 54 health health NN cord-005646-xhx9pzhj 4330 55 . . . cord-005646-xhx9pzhj 4331 1 • • NNP cord-005646-xhx9pzhj 4331 2 analyse analyse VB cord-005646-xhx9pzhj 4331 3 the the DT cord-005646-xhx9pzhj 4331 4 differences difference NNS cord-005646-xhx9pzhj 4331 5 between between IN cord-005646-xhx9pzhj 4331 6 each each DT cord-005646-xhx9pzhj 4331 7 urdt urdt NN cord-005646-xhx9pzhj 4331 8 . . . cord-005646-xhx9pzhj 4332 1 Method method NN cord-005646-xhx9pzhj 4332 2 : : : cord-005646-xhx9pzhj 4333 1 NI NI NNP cord-005646-xhx9pzhj 4333 2 criteria criterion NNS cord-005646-xhx9pzhj 4333 3 were be VBD cord-005646-xhx9pzhj 4333 4 defined define VBN cord-005646-xhx9pzhj 4333 5 by by IN cord-005646-xhx9pzhj 4333 6 the the DT cord-005646-xhx9pzhj 4333 7 Rt Rt NNP cord-005646-xhx9pzhj 4333 8 ~ ~ NNP cord-005646-xhx9pzhj 4333 9 A a DT cord-005646-xhx9pzhj 4333 10 PED PED NNP cord-005646-xhx9pzhj 4333 11 Group Group NNP cord-005646-xhx9pzhj 4333 12 according accord VBG cord-005646-xhx9pzhj 4333 13 to to IN cord-005646-xhx9pzhj 4333 14 CDC CDC NNP cord-005646-xhx9pzhj 4333 15 criteria criterion NNS cord-005646-xhx9pzhj 4333 16 . . . cord-005646-xhx9pzhj 4334 1 All all DT cord-005646-xhx9pzhj 4334 2 data datum NNS cord-005646-xhx9pzhj 4334 3 were be VBD cord-005646-xhx9pzhj 4334 4 collected collect VBN cord-005646-xhx9pzhj 4334 5 by by IN cord-005646-xhx9pzhj 4334 6 a a DT cord-005646-xhx9pzhj 4334 7 nursing nursing NN cord-005646-xhx9pzhj 4334 8 and and CC cord-005646-xhx9pzhj 4334 9 medical medical JJ cord-005646-xhx9pzhj 4334 10 team team NN cord-005646-xhx9pzhj 4334 11 . . . cord-005646-xhx9pzhj 4335 1 Data datum NNS cord-005646-xhx9pzhj 4335 2 3vere 3vere CD cord-005646-xhx9pzhj 4335 3 dealed deal VBD cord-005646-xhx9pzhj 4335 4 with with IN cord-005646-xhx9pzhj 4335 5 EPI EPI NNP cord-005646-xhx9pzhj 4335 6 INFO INFO NNP cord-005646-xhx9pzhj 4335 7 software software NN cord-005646-xhx9pzhj 4335 8 . . . cord-005646-xhx9pzhj 4336 1 All all DT cord-005646-xhx9pzhj 4336 2 u u NNP cord-005646-xhx9pzhj 4336 3 - - HYPH cord-005646-xhx9pzhj 4336 4 dections dection NNS cord-005646-xhx9pzhj 4336 5 data datum NNS cord-005646-xhx9pzhj 4336 6 were be VBD cord-005646-xhx9pzhj 4336 7 validated validate VBN cord-005646-xhx9pzhj 4336 8 by by IN cord-005646-xhx9pzhj 4336 9 an an DT cord-005646-xhx9pzhj 4336 10 external external JJ cord-005646-xhx9pzhj 4336 11 mvestigatoL mvestigatoL NNP cord-005646-xhx9pzhj 4336 12 : : : cord-005646-xhx9pzhj 4336 13 4 4 CD cord-005646-xhx9pzhj 4336 14 525 525 CD cord-005646-xhx9pzhj 4336 15 patients patient NNS cord-005646-xhx9pzhj 4336 16 who who WP cord-005646-xhx9pzhj 4336 17 stay stay VBP cord-005646-xhx9pzhj 4336 18 more more JJR cord-005646-xhx9pzhj 4336 19 than than IN cord-005646-xhx9pzhj 4336 20 48 48 CD cord-005646-xhx9pzhj 4336 21 hours hour NNS cord-005646-xhx9pzhj 4336 22 in in IN cord-005646-xhx9pzhj 4336 23 an an DT cord-005646-xhx9pzhj 4336 24 ICU ICU NNP cord-005646-xhx9pzhj 4336 25 were be VBD cord-005646-xhx9pzhj 4336 26 included include VBN cord-005646-xhx9pzhj 4336 27 over over IN cord-005646-xhx9pzhj 4336 28 a a DT cord-005646-xhx9pzhj 4336 29 14 14 CD cord-005646-xhx9pzhj 4336 30 months month NNS cord-005646-xhx9pzhj 4336 31 period period NN cord-005646-xhx9pzhj 4336 32 . . . cord-005646-xhx9pzhj 4337 1 68 68 CD cord-005646-xhx9pzhj 4337 2 % % NN cord-005646-xhx9pzhj 4337 3 were be VBD cord-005646-xhx9pzhj 4337 4 newborns newborn NNS cord-005646-xhx9pzhj 4337 5 , , , cord-005646-xhx9pzhj 4337 6 19 19 CD cord-005646-xhx9pzhj 4337 7 % % NN cord-005646-xhx9pzhj 4337 8 infants infant NNS cord-005646-xhx9pzhj 4337 9 and and CC cord-005646-xhx9pzhj 4337 10 , , , cord-005646-xhx9pzhj 4337 11 13 13 CD cord-005646-xhx9pzhj 4337 12 % % NN cord-005646-xhx9pzhj 4337 13 children child NNS cord-005646-xhx9pzhj 4337 14 . . . cord-005646-xhx9pzhj 4338 1 371 371 CD cord-005646-xhx9pzhj 4338 2 NI NI NNP cord-005646-xhx9pzhj 4338 3 were be VBD cord-005646-xhx9pzhj 4338 4 idenlified idenlifie VBN cord-005646-xhx9pzhj 4338 5 among among IN cord-005646-xhx9pzhj 4338 6 Sll Sll NNP cord-005646-xhx9pzhj 4338 7 patients patient NNS cord-005646-xhx9pzhj 4338 8 , , , cord-005646-xhx9pzhj 4338 9 The the DT cord-005646-xhx9pzhj 4338 10 overall overall JJ cord-005646-xhx9pzhj 4338 11 NI NI NNP cord-005646-xhx9pzhj 4338 12 incidence incidence NN cord-005646-xhx9pzhj 4338 13 rates rate NNS cord-005646-xhx9pzhj 4338 14 was be VBD cord-005646-xhx9pzhj 4338 15 8,2 8,2 CD cord-005646-xhx9pzhj 4338 16 % % NN cord-005646-xhx9pzhj 4338 17 and and CC cord-005646-xhx9pzhj 4338 18 5,9 5,9 CD cord-005646-xhx9pzhj 4338 19 person person NN cord-005646-xhx9pzhj 4338 20 day day NN cord-005646-xhx9pzhj 4338 21 , , , cord-005646-xhx9pzhj 4338 22 Septicemia septicemia NN cord-005646-xhx9pzhj 4338 23 was be VBD cord-005646-xhx9pzhj 4338 24 the the DT cord-005646-xhx9pzhj 4338 25 first first JJ cord-005646-xhx9pzhj 4338 26 cause cause NN cord-005646-xhx9pzhj 4338 27 of of IN cord-005646-xhx9pzhj 4338 28 NI NI NNP cord-005646-xhx9pzhj 4338 29 ( ( -LRB- cord-005646-xhx9pzhj 4338 30 50 50 CD cord-005646-xhx9pzhj 4338 31 % % NN cord-005646-xhx9pzhj 4338 32 ) ) -RRB- cord-005646-xhx9pzhj 4338 33 . . . cord-005646-xhx9pzhj 4339 1 Staphylococcus Staphylococcus NNP cord-005646-xhx9pzhj 4339 2 epidermidis epidermidi NNS cord-005646-xhx9pzhj 4339 3 were be VBD cord-005646-xhx9pzhj 4339 4 isolated isolate VBN cord-005646-xhx9pzhj 4339 5 in in IN cord-005646-xhx9pzhj 4339 6 60 60 CD cord-005646-xhx9pzhj 4339 7 % % NN cord-005646-xhx9pzhj 4339 8 of of IN cord-005646-xhx9pzhj 4339 9 septicemia septicemia NN cord-005646-xhx9pzhj 4339 10 cases case NNS cord-005646-xhx9pzhj 4339 11 . . . cord-005646-xhx9pzhj 4340 1 Pneumonia pneumonia NN cord-005646-xhx9pzhj 4340 2 was be VBD cord-005646-xhx9pzhj 4340 3 the the DT cord-005646-xhx9pzhj 4340 4 other other JJ cord-005646-xhx9pzhj 4340 5 main main JJ cord-005646-xhx9pzhj 4340 6 NI NI NNP cord-005646-xhx9pzhj 4340 7 ( ( -LRB- cord-005646-xhx9pzhj 4340 8 41 41 CD cord-005646-xhx9pzhj 4340 9 % % NN cord-005646-xhx9pzhj 4340 10 ) ) -RRB- cord-005646-xhx9pzhj 4340 11 with with IN cord-005646-xhx9pzhj 4340 12 Gram Gram NNP cord-005646-xhx9pzhj 4340 13 negatwe negatwe NN cord-005646-xhx9pzhj 4340 14 bacille bacille NN cord-005646-xhx9pzhj 4340 15 isolated isolate VBD cord-005646-xhx9pzhj 4340 16 m m NNP cord-005646-xhx9pzhj 4340 17 53 53 CD cord-005646-xhx9pzhj 4340 18 % % NN cord-005646-xhx9pzhj 4340 19 ( ( -LRB- cord-005646-xhx9pzhj 4340 20 40 40 CD cord-005646-xhx9pzhj 4340 21 % % NN cord-005646-xhx9pzhj 4340 22 of of IN cord-005646-xhx9pzhj 4340 23 them -PRON- PRP cord-005646-xhx9pzhj 4340 24 beei beei NNP cord-005646-xhx9pzhj 4340 25 , , , cord-005646-xhx9pzhj 4340 26 ng ng NNP cord-005646-xhx9pzhj 4340 27 Fseudomonas Fseudomonas NNP cord-005646-xhx9pzhj 4340 28 ) ) -RRB- cord-005646-xhx9pzhj 4341 1 Accordmg Accordmg NNP cord-005646-xhx9pzhj 4341 2 to to IN cord-005646-xhx9pzhj 4341 3 age age NN cord-005646-xhx9pzhj 4341 4 , , , cord-005646-xhx9pzhj 4341 5 the the DT cord-005646-xhx9pzhj 4341 6 septicemia septicemia NN cord-005646-xhx9pzhj 4341 7 mcidence mcidence NN cord-005646-xhx9pzhj 4341 8 rate rate NN cord-005646-xhx9pzhj 4341 9 varied vary VBN cord-005646-xhx9pzhj 4341 10 from from IN cord-005646-xhx9pzhj 4341 11 6,8 6,8 CD cord-005646-xhx9pzhj 4342 1 ~. ~. NNP cord-005646-xhx9pzhj 4342 2 , , , cord-005646-xhx9pzhj 4342 3 to to IN cord-005646-xhx9pzhj 4342 4 10.9 10.9 CD cord-005646-xhx9pzhj 4342 5 % % NN cord-005646-xhx9pzhj 4342 6 , , , cord-005646-xhx9pzhj 4342 7 , , , cord-005646-xhx9pzhj 4342 8 catheter catheter NN cord-005646-xhx9pzhj 4342 9 / / SYM cord-005646-xhx9pzhj 4342 10 day day NN cord-005646-xhx9pzhj 4342 11 and and CC cord-005646-xhx9pzhj 4342 12 pneumonia pneumonia NN cord-005646-xhx9pzhj 4342 13 incidence incidence NN cord-005646-xhx9pzhj 4342 14 rate rate NN cord-005646-xhx9pzhj 4342 15 from from IN cord-005646-xhx9pzhj 4342 16 3,9 3,9 CD cord-005646-xhx9pzhj 4342 17 % % NN cord-005646-xhx9pzhj 4342 18 , , , cord-005646-xhx9pzhj 4342 19 to to IN cord-005646-xhx9pzhj 4342 20 7,3 7,3 CD cord-005646-xhx9pzhj 4342 21 % % NN cord-005646-xhx9pzhj 4342 22 ventilation ventilation NN cord-005646-xhx9pzhj 4342 23 / / SYM cord-005646-xhx9pzhj 4342 24 daywith daywith NN cord-005646-xhx9pzhj 4342 25 the the DT cord-005646-xhx9pzhj 4342 26 lowest low JJS cord-005646-xhx9pzhj 4342 27 rate rate NN cord-005646-xhx9pzhj 4342 28 for for IN cord-005646-xhx9pzhj 4342 29 newborns newborn NNS cord-005646-xhx9pzhj 4342 30 . . . cord-005646-xhx9pzhj 4343 1 : : : cord-005646-xhx9pzhj 4343 2 this this DT cord-005646-xhx9pzhj 4343 3 survey survey NN cord-005646-xhx9pzhj 4343 4 was be VBD cord-005646-xhx9pzhj 4343 5 possible possible JJ cord-005646-xhx9pzhj 4343 6 thanks thank NNS cord-005646-xhx9pzhj 4343 7 to to IN cord-005646-xhx9pzhj 4343 8 the the DT cord-005646-xhx9pzhj 4343 9 collaboration collaboration NN cord-005646-xhx9pzhj 4343 10 between between IN cord-005646-xhx9pzhj 4343 11 laboratories laboratory NNS cord-005646-xhx9pzhj 4343 12 , , , cord-005646-xhx9pzhj 4343 13 bacteriologist bacteriologist NN cord-005646-xhx9pzhj 4343 14 , , , cord-005646-xhx9pzhj 4343 15 physicians physician NNS cord-005646-xhx9pzhj 4343 16 and and CC cord-005646-xhx9pzhj 4343 17 nurses nurse NNS cord-005646-xhx9pzhj 4343 18 , , , cord-005646-xhx9pzhj 4343 19 and and CC cord-005646-xhx9pzhj 4343 20 allowed allow VBN cord-005646-xhx9pzhj 4343 21 each each DT cord-005646-xhx9pzhj 4343 22 concerned concerned JJ cord-005646-xhx9pzhj 4343 23 unit unit NN cord-005646-xhx9pzhj 4343 24 to to TO cord-005646-xhx9pzhj 4343 25 work work VB cord-005646-xhx9pzhj 4343 26 together together RB cord-005646-xhx9pzhj 4343 27 in in IN cord-005646-xhx9pzhj 4343 28 ~ ~ NFP cord-005646-xhx9pzhj 4343 29 tead tead XX cord-005646-xhx9pzhj 4343 30 of of IN cord-005646-xhx9pzhj 4343 31 every every DT cord-005646-xhx9pzhj 4343 32 one one CD cord-005646-xhx9pzhj 4343 33 in in IN cord-005646-xhx9pzhj 4343 34 his -PRON- PRP$ cord-005646-xhx9pzhj 4343 35 own own JJ cord-005646-xhx9pzhj 4343 36 field field NN cord-005646-xhx9pzhj 4343 37 . . . cord-005646-xhx9pzhj 4343 38 ' ' '' cord-005646-xhx9pzhj 4344 1 lhe lhe NNP cord-005646-xhx9pzhj 4344 2 results result NNS cord-005646-xhx9pzhj 4344 3 of of IN cord-005646-xhx9pzhj 4344 4 this this DT cord-005646-xhx9pzhj 4344 5 survey survey NN cord-005646-xhx9pzhj 4344 6 bring bring VBP cord-005646-xhx9pzhj 4344 7 changes change NNS cord-005646-xhx9pzhj 4344 8 in in IN cord-005646-xhx9pzhj 4344 9 attlhades attlhade NNS cord-005646-xhx9pzhj 4344 10 and and CC cord-005646-xhx9pzhj 4344 11 empower empower VB cord-005646-xhx9pzhj 4344 12 the the DT cord-005646-xhx9pzhj 4344 13 different different JJ cord-005646-xhx9pzhj 4344 14 team team NN cord-005646-xhx9pzhj 4344 15 work work NN cord-005646-xhx9pzhj 4345 1 The the DT cord-005646-xhx9pzhj 4345 2 next next JJ cord-005646-xhx9pzhj 4345 3 step step NN cord-005646-xhx9pzhj 4345 4 is be VBZ cord-005646-xhx9pzhj 4345 5 to to TO cord-005646-xhx9pzhj 4345 6 analyse analyse VB cord-005646-xhx9pzhj 4345 7 the the DT cord-005646-xhx9pzhj 4345 8 ditferent ditferent JJ cord-005646-xhx9pzhj 4345 9 nurses nurse NNS cord-005646-xhx9pzhj 4345 10 procedures procedure NNS cord-005646-xhx9pzhj 4345 11 of of IN cord-005646-xhx9pzhj 4345 12 indwelling indwell VBG cord-005646-xhx9pzhj 4345 13 central central JJ cord-005646-xhx9pzhj 4345 14 venous venous JJ cord-005646-xhx9pzhj 4345 15 catheter catheter NN cord-005646-xhx9pzhj 4345 16 in in IN cord-005646-xhx9pzhj 4345 17 each each DT cord-005646-xhx9pzhj 4345 18 unit unit NN cord-005646-xhx9pzhj 4345 19 ar)d ar)d PRP cord-005646-xhx9pzhj 4345 20 implement implement VB cord-005646-xhx9pzhj 4345 21 a a DT cord-005646-xhx9pzhj 4345 22 NI NI NNP cord-005646-xhx9pzhj 4345 23 quatity quatity NN cord-005646-xhx9pzhj 4345 24 Care Care NNP cord-005646-xhx9pzhj 4345 25 . . . cord-005646-xhx9pzhj 4346 1 program program NN cord-005646-xhx9pzhj 4346 2 in in IN cord-005646-xhx9pzhj 4346 3 all all DT cord-005646-xhx9pzhj 4346 4 NICU NICU NNP cord-005646-xhx9pzhj 4346 5 anti anti JJ cord-005646-xhx9pzhj 4346 6 PICU PICU NNP cord-005646-xhx9pzhj 4346 7 . . . cord-005646-xhx9pzhj 4347 1 V~,~JL V~,~JL . cord-005646-xhx9pzhj 4348 1 ~J~'V ~j~'v JJ cord-005646-xhx9pzhj 4348 2 ~ ~ NNP cord-005646-xhx9pzhj 4348 3 y y NNP cord-005646-xhx9pzhj 4348 4 : : : cord-005646-xhx9pzhj 4348 5 new new NNP cord-005646-xhx9pzhj 4348 6 born bear VBN cord-005646-xhx9pzhj 4348 7 in~ in~ NNP cord-005646-xhx9pzhj 4349 1 ra ra JJ cord-005646-xhx9pzhj 4349 2 - - JJ cord-005646-xhx9pzhj 4349 3 v~6nous v~6nous JJ cord-005646-xhx9pzhj 4349 4 drugs drug NNS cord-005646-xhx9pzhj 4350 1 ~md ~md NNP cord-005646-xhx9pzhj 4351 1 lheir lheir NNP cord-005646-xhx9pzhj 4351 2 pr pr NNP cord-005646-xhx9pzhj 4352 1 ~Taration ~Taration NFP cord-005646-xhx9pzhj 4352 2 mcounter mcounter NN cord-005646-xhx9pzhj 4352 3 a a DT cord-005646-xhx9pzhj 4352 4 lot lot NN cord-005646-xhx9pzhj 4352 5 of of IN cord-005646-xhx9pzhj 4352 6 risk risk NN cord-005646-xhx9pzhj 4352 7 ~)f ~)f NN cord-005646-xhx9pzhj 4352 8 utters utter VBZ cord-005646-xhx9pzhj 4352 9 , , , cord-005646-xhx9pzhj 4352 10 due due IN cord-005646-xhx9pzhj 4352 11 to to IN cord-005646-xhx9pzhj 4352 12 inadapted inadapted JJ cord-005646-xhx9pzhj 4352 13 conditionn conditionn NNP cord-005646-xhx9pzhj 4352 14 ~ ~ NFP cord-005646-xhx9pzhj 4352 15 ng ng NNP cord-005646-xhx9pzhj 4352 16 to to IN cord-005646-xhx9pzhj 4352 17 podia)eric podia)eric NNP cord-005646-xhx9pzhj 4352 18 and and CC cord-005646-xhx9pzhj 4352 19 minimal minimal JJ cord-005646-xhx9pzhj 4352 20 amount amount NN cord-005646-xhx9pzhj 4353 1 injec~.~d injec~.~d RB cord-005646-xhx9pzhj 4353 2 , , , cord-005646-xhx9pzhj 4353 3 Th~ Th~ NNP cord-005646-xhx9pzhj 4353 4 study study NN cord-005646-xhx9pzhj 4353 5 t t NN cord-005646-xhx9pzhj 4354 1 ~ed ~ed NNP cord-005646-xhx9pzhj 4354 2 to to TO cord-005646-xhx9pzhj 4354 3 evaluate evaluate VB cord-005646-xhx9pzhj 4354 4 degrees degree NNS cord-005646-xhx9pzhj 4354 5 of of IN cord-005646-xhx9pzhj 4354 6 do.~age do.~age NN cord-005646-xhx9pzhj 4354 7 er er UH cord-005646-xhx9pzhj 4354 8 ~ ~ NFP cord-005646-xhx9pzhj 4354 9 o~ o~ CD cord-005646-xhx9pzhj 4354 10 dye dye NN cord-005646-xhx9pzhj 4354 11 tt tt NNP cord-005646-xhx9pzhj 4354 12 ) ) -RRB- cord-005646-xhx9pzhj 4354 13 dru~ dru~ NNP cord-005646-xhx9pzhj 4354 14 preparaek preparaek NN cord-005646-xhx9pzhj 4354 15 , , , cord-005646-xhx9pzhj 4354 16 n n NN cord-005646-xhx9pzhj 4354 17 i~ i~ XX cord-005646-xhx9pzhj 4355 1 nc,:,~atol nc,:,~atol NNP cord-005646-xhx9pzhj 4355 2 ~ ~ NFP cord-005646-xhx9pzhj 4355 3 gy gy XX cord-005646-xhx9pzhj 4355 4 and and CC cord-005646-xhx9pzhj 4356 1 to to TO cord-005646-xhx9pzhj 4356 2 come come VB cord-005646-xhx9pzhj 4356 3 out out RP cord-005646-xhx9pzhj 4356 4 w w NN cord-005646-xhx9pzhj 4357 1 ~th ~th NNP cord-005646-xhx9pzhj 4357 2 ~ ~ NFP cord-005646-xhx9pzhj 4357 3 method method NN cord-005646-xhx9pzhj 4357 4 of of IN cord-005646-xhx9pzhj 4357 5 dihttion dihttion NN cord-005646-xhx9pzhj 4357 6 able able JJ cord-005646-xhx9pzhj 4357 7 to to TO cord-005646-xhx9pzhj 4357 8 reduce reduce VB cord-005646-xhx9pzhj 4357 9 risk risk NN cord-005646-xhx9pzhj 4357 10 to to IN cord-005646-xhx9pzhj 4357 11 minima minima FW cord-005646-xhx9pzhj 4357 12 ( ( -LRB- cord-005646-xhx9pzhj 4357 13 errors error NNS cord-005646-xhx9pzhj 4357 14 _ _ VBP cord-005646-xhx9pzhj 4357 15 < < XX cord-005646-xhx9pzhj 4357 16 5 5 CD cord-005646-xhx9pzhj 4357 17 % % NN cord-005646-xhx9pzhj 4357 18 ) ) -RRB- cord-005646-xhx9pzhj 4358 1 At at IN cord-005646-xhx9pzhj 4358 2 the the DT cord-005646-xhx9pzhj 4358 3 ~eme ~eme NNP cord-005646-xhx9pzhj 4358 4 t t XX cord-005646-xhx9pzhj 4358 5 ~ ~ NFP cord-005646-xhx9pzhj 4358 6 me -PRON- PRP cord-005646-xhx9pzhj 4358 7 , , , cord-005646-xhx9pzhj 4358 8 ¢o~,~x ¢o~,~x NNP cord-005646-xhx9pzhj 4358 9 - - HYPH cord-005646-xhx9pzhj 4358 10 tueaces tueace NNS cord-005646-xhx9pzhj 4358 11 on on IN cord-005646-xhx9pzhj 4358 12 cost cost NN cord-005646-xhx9pzhj 4358 13 were be VBD cord-005646-xhx9pzhj 4358 14 studioJ studioj XX cord-005646-xhx9pzhj 4359 1 Methnd~ Methnd~ NNS cord-005646-xhx9pzhj 4359 2 : : : cord-005646-xhx9pzhj 4360 1 Amikacine Amikacine NNP cord-005646-xhx9pzhj 4360 2 was be VBD cord-005646-xhx9pzhj 4360 3 choosen choosen VBN cord-005646-xhx9pzhj 4360 4 because because IN cord-005646-xhx9pzhj 4360 5 this this DT cord-005646-xhx9pzhj 4360 6 antibiotic antibiotic NN cord-005646-xhx9pzhj 4360 7 is be VBZ cord-005646-xhx9pzhj 4360 8 regularly regularly RB cord-005646-xhx9pzhj 4360 9 ~,~l ~,~l NFP cord-005646-xhx9pzhj 4360 10 in in IN cord-005646-xhx9pzhj 4360 11 neonatology neonatology NN cord-005646-xhx9pzhj 4360 12 unit unit NN cord-005646-xhx9pzhj 4360 13 and and CC cord-005646-xhx9pzhj 4360 14 its -PRON- PRP$ cord-005646-xhx9pzhj 4360 15 dosage dosage NN cord-005646-xhx9pzhj 4360 16 is be VBZ cord-005646-xhx9pzhj 4360 17 easily easily RB cord-005646-xhx9pzhj 4360 18 used use VBN cord-005646-xhx9pzhj 4360 19 by by IN cord-005646-xhx9pzhj 4360 20 standardiaud standardiaud NNP cord-005646-xhx9pzhj 4360 21 method method NN cord-005646-xhx9pzhj 4360 22 , , , cord-005646-xhx9pzhj 4360 23 30 30 CD cord-005646-xhx9pzhj 4360 24 Amikacine Amikacine NNP cord-005646-xhx9pzhj 4360 25 doses dose NNS cord-005646-xhx9pzhj 4360 26 ( ( -LRB- cord-005646-xhx9pzhj 4360 27 15 15 CD cord-005646-xhx9pzhj 4360 28 , , , cord-005646-xhx9pzhj 4360 29 23 23 CD cord-005646-xhx9pzhj 4360 30 mg mg NNP cord-005646-xhx9pzhj 4360 31 doses dose NNS cord-005646-xhx9pzhj 4360 32 and and CC cord-005646-xhx9pzhj 4360 33 15 15 CD cord-005646-xhx9pzhj 4360 34 , , , cord-005646-xhx9pzhj 4360 35 12 12 CD cord-005646-xhx9pzhj 4360 36 mg mg NNP cord-005646-xhx9pzhj 4360 37 doses dose NNS cord-005646-xhx9pzhj 4360 38 ) ) -RRB- cord-005646-xhx9pzhj 4360 39 were be VBD cord-005646-xhx9pzhj 4360 40 prepared prepare VBN cord-005646-xhx9pzhj 4360 41 " " '' cord-005646-xhx9pzhj 4360 42 by by IN cord-005646-xhx9pzhj 4360 43 15 15 CD cord-005646-xhx9pzhj 4360 44 nurse~ nurse~ NNP cord-005646-xhx9pzhj 4360 45 form form NN cord-005646-xhx9pzhj 4360 46 50 50 CD cord-005646-xhx9pzhj 4360 47 mg mg NN cord-005646-xhx9pzhj 4360 48 for for IN cord-005646-xhx9pzhj 4360 49 1 1 CD cord-005646-xhx9pzhj 4360 50 m m CD cord-005646-xhx9pzhj 4360 51 ) ) -RRB- cord-005646-xhx9pzhj 4360 52 vial vial NN cord-005646-xhx9pzhj 4360 53 . . . cord-005646-xhx9pzhj 4361 1 Each each DT cord-005646-xhx9pzhj 4361 2 dose dose NN cord-005646-xhx9pzhj 4361 3 w'a~ w'a~ NNP cord-005646-xhx9pzhj 4361 4 diluted dilute VBD cord-005646-xhx9pzhj 4361 5 to to TO cord-005646-xhx9pzhj 4361 6 obtain obtain VB cord-005646-xhx9pzhj 4361 7 2 2 CD cord-005646-xhx9pzhj 4361 8 mI mI NNP cord-005646-xhx9pzhj 4361 9 volume volume NN cord-005646-xhx9pzhj 4361 10 , , , cord-005646-xhx9pzhj 4361 11 tallowing tallowe VBG cord-005646-xhx9pzhj 4361 12 usual usual JJ cord-005646-xhx9pzhj 4361 13 ward ward NN cord-005646-xhx9pzhj 4361 14 method method NN cord-005646-xhx9pzhj 4361 15 , , , cord-005646-xhx9pzhj 4362 1 For for IN cord-005646-xhx9pzhj 4362 2 each each DT cord-005646-xhx9pzhj 4362 3 dilution dilution NN cord-005646-xhx9pzhj 4362 4 , , , cord-005646-xhx9pzhj 4362 5 Amikacine Amikacine NNP cord-005646-xhx9pzhj 4362 6 con con XX cord-005646-xhx9pzhj 4363 1 < < XX cord-005646-xhx9pzhj 4363 2 entrati('m entrati('m NNP cord-005646-xhx9pzhj 4364 1 and and CC cord-005646-xhx9pzhj 4364 2 it -PRON- PRP cord-005646-xhx9pzhj 4364 3 , , , cord-005646-xhx9pzhj 4364 4 s s NNP cord-005646-xhx9pzhj 4364 5 volume volume NN cord-005646-xhx9pzhj 4364 6 was be VBD cord-005646-xhx9pzhj 4364 7 measured measure VBN cord-005646-xhx9pzhj 4364 8 and and CC cord-005646-xhx9pzhj 4364 9 used use VBN cord-005646-xhx9pzhj 4364 10 equipment equipment NN cord-005646-xhx9pzhj 4364 11 for for IN cord-005646-xhx9pzhj 4364 12 preparation preparation NN cord-005646-xhx9pzhj 4364 13 wa~ wa~ NN cord-005646-xhx9pzhj 4364 14 regi regi NNP cord-005646-xhx9pzhj 4364 15 ~ ~ NFP cord-005646-xhx9pzhj 4364 16 tred tred NNP cord-005646-xhx9pzhj 4364 17 . . . cord-005646-xhx9pzhj 4365 1 10 10 CD cord-005646-xhx9pzhj 4365 2 " " `` cord-005646-xhx9pzhj 4365 3 first first JJ cord-005646-xhx9pzhj 4365 4 s01utJ(m s01utJ(m NNP cord-005646-xhx9pzhj 4365 5 " " '' cord-005646-xhx9pzhj 4365 6 were be VBD cord-005646-xhx9pzhj 4365 7 prepared prepare VBN cord-005646-xhx9pzhj 4365 8 diluting diluting NN cord-005646-xhx9pzhj 4366 1 ~t'~ ~t'~ NFP cord-005646-xhx9pzhj 4367 1 mg mg NNP cord-005646-xhx9pzhj 4367 2 Amikacine Amikacine NNP cord-005646-xhx9pzhj 4367 3 pouder pouder NN cord-005646-xhx9pzhj 4367 4 inn inn NNP cord-005646-xhx9pzhj 4367 5 51 51 CD cord-005646-xhx9pzhj 4367 6 ) ) -RRB- cord-005646-xhx9pzhj 4368 1 ml ml NNP cord-005646-xhx9pzhj 4368 2 glucnse glucnse NN cord-005646-xhx9pzhj 4368 3 solution solution NN cord-005646-xhx9pzhj 4368 4 bag bag NN cord-005646-xhx9pzhj 4368 5 ( ( -LRB- cord-005646-xhx9pzhj 4368 6 Viaflex Viaflex NNP cord-005646-xhx9pzhj 4368 7 Baxter Baxter NNP cord-005646-xhx9pzhj 4368 8 bag bag NN cord-005646-xhx9pzhj 4368 9 with with IN cord-005646-xhx9pzhj 4368 10 transfer transfer NN cord-005646-xhx9pzhj 4368 11 cap cap NN cord-005646-xhx9pzhj 4368 12 ) ) -RRB- cord-005646-xhx9pzhj 4368 13 , , . cord-005646-xhx9pzhj 4369 1 From from IN cord-005646-xhx9pzhj 4369 2 tho tho NN cord-005646-xhx9pzhj 4369 3 ~ ~ NFP cord-005646-xhx9pzhj 4369 4 e e LS cord-005646-xhx9pzhj 4369 5 " " `` cord-005646-xhx9pzhj 4369 6 first first JJ cord-005646-xhx9pzhj 4369 7 solution solution NN cord-005646-xhx9pzhj 4369 8 " " '' cord-005646-xhx9pzhj 4369 9 15 15 CD cord-005646-xhx9pzhj 4369 10 doses dose NNS cord-005646-xhx9pzhj 4369 11 at at IN cord-005646-xhx9pzhj 4369 12 23 23 CD cord-005646-xhx9pzhj 4369 13 mg mg NN cord-005646-xhx9pzhj 4369 14 and and CC cord-005646-xhx9pzhj 4369 15 15 15 CD cord-005646-xhx9pzhj 4369 16 doses dose NNS cord-005646-xhx9pzhj 4369 17 of of IN cord-005646-xhx9pzhj 4369 18 ~2 ~2 CD cord-005646-xhx9pzhj 4369 19 rng rng NNP cord-005646-xhx9pzhj 4369 20 were be VBD cord-005646-xhx9pzhj 4369 21 prepared prepare VBN cord-005646-xhx9pzhj 4369 22 , , , cord-005646-xhx9pzhj 4369 23 Amik Amik NNP cord-005646-xhx9pzhj 4369 24 ~ ~ NFP cord-005646-xhx9pzhj 4369 25 cine cine NNP cord-005646-xhx9pzhj 4369 26 coc coc NNP cord-005646-xhx9pzhj 4369 27 , , , cord-005646-xhx9pzhj 4369 28 cenir,)tmn cenir,)tmn NNP cord-005646-xhx9pzhj 4369 29 for for IN cord-005646-xhx9pzhj 4369 30 each each DT cord-005646-xhx9pzhj 4369 31 preparabon preparabon NN cord-005646-xhx9pzhj 4369 32 and and CC cord-005646-xhx9pzhj 4369 33 their -PRON- PRP$ cord-005646-xhx9pzhj 4369 34 volume volume NN cord-005646-xhx9pzhj 4369 35 were be VBD cord-005646-xhx9pzhj 4369 36 measured measure VBN cord-005646-xhx9pzhj 4369 37 , , , cord-005646-xhx9pzhj 4369 38 ai,~n ai,~n NNP cord-005646-xhx9pzhj 4369 39 ntttl~,ber ntttl~,ber NN cord-005646-xhx9pzhj 4369 40 of of IN cord-005646-xhx9pzhj 4369 41 seringe seringe NNP cord-005646-xhx9pzhj 4369 42 were be VBD cord-005646-xhx9pzhj 4369 43 tOunted tounte VBN cord-005646-xhx9pzhj 4369 44 . . . cord-005646-xhx9pzhj 4370 1 First first JJ cord-005646-xhx9pzhj 4370 2 soiuhon soiuhon NNP cord-005646-xhx9pzhj 4370 3 staeiiity staeiiity NNP cord-005646-xhx9pzhj 4370 4 was be VBD cord-005646-xhx9pzhj 4370 5 conrroieo conrroieo NNP cord-005646-xhx9pzhj 4370 6 aher aher NNP cord-005646-xhx9pzhj 4370 7 one one CD cord-005646-xhx9pzhj 4370 8 week week NN cord-005646-xhx9pzhj 4370 9 conservation conservation NN cord-005646-xhx9pzhj 4370 10 at at IN cord-005646-xhx9pzhj 4370 11 + + CD cord-005646-xhx9pzhj 4370 12 4'>C. 4'>c. CD cord-005646-xhx9pzhj 4371 1 AmJkacine AmJkacine NNP cord-005646-xhx9pzhj 4371 2 concentration concentration NN cord-005646-xhx9pzhj 4371 3 were be VBD cord-005646-xhx9pzhj 4371 4 measured measure VBN cord-005646-xhx9pzhj 4371 5 by by IN cord-005646-xhx9pzhj 4371 6 fluorescence fluorescence NN cord-005646-xhx9pzhj 4371 7 process process NN cord-005646-xhx9pzhj 4371 8 ( ( -LRB- cord-005646-xhx9pzhj 4371 9 TDX TDX NNP cord-005646-xhx9pzhj 4371 10 ABBOTT ABBOTT NNP cord-005646-xhx9pzhj 4371 11 ) ) -RRB- cord-005646-xhx9pzhj 4371 12 after after IN cord-005646-xhx9pzhj 4371 13 sample sample NN cord-005646-xhx9pzhj 4371 14 dilurion dilurion NN cord-005646-xhx9pzhj 4371 15 . . . cord-005646-xhx9pzhj 4372 1 On on IN cord-005646-xhx9pzhj 4372 2 a a DT cord-005646-xhx9pzhj 4372 3 10 10 CD cord-005646-xhx9pzhj 4372 4 mg mg NNP cord-005646-xhx9pzhj 4372 5 / / SYM cord-005646-xhx9pzhj 4372 6 l l NN cord-005646-xhx9pzhj 4372 7 sample sample NN cord-005646-xhx9pzhj 4372 8 , , , cord-005646-xhx9pzhj 4372 9 tovhnical tovhnical JJ cord-005646-xhx9pzhj 4372 10 reliahility reliahility NN cord-005646-xhx9pzhj 4373 1 show~ show~ NNP cord-005646-xhx9pzhj 4374 1 > > XX cord-005646-xhx9pzhj 4375 1 9~ 9~ CD cord-005646-xhx9pzhj 4375 2 % % NN cord-005646-xhx9pzhj 4375 3 Of of IN cord-005646-xhx9pzhj 4375 4 result result NN cord-005646-xhx9pzhj 4375 5 mpmductlon mpmductlon NN cord-005646-xhx9pzhj 4375 6 and and CC cord-005646-xhx9pzhj 4375 7 < < NNP cord-005646-xhx9pzhj 4375 8 5 5 CD cord-005646-xhx9pzhj 4375 9 % % NN cord-005646-xhx9pzhj 4375 10 of of IN cord-005646-xhx9pzhj 4375 11 variation variation NN cord-005646-xhx9pzhj 4375 12 due due IN cord-005646-xhx9pzhj 4375 13 to to IN cord-005646-xhx9pzhj 4375 14 dilutions dilution NNS cord-005646-xhx9pzhj 4375 15 . . . cord-005646-xhx9pzhj 4376 1 Results result NNS cord-005646-xhx9pzhj 4376 2 : : : cord-005646-xhx9pzhj 4376 3 when when WRB cord-005646-xhx9pzhj 4376 4 Amikacine Amikacine NNP cord-005646-xhx9pzhj 4376 5 injection injection NN cord-005646-xhx9pzhj 4376 6 werv werv NN cord-005646-xhx9pzhj 4376 7 pro.pared pro.pared NNP cord-005646-xhx9pzhj 4376 8 from from IN cord-005646-xhx9pzhj 4376 9 Araikacme Araikacme NNP cord-005646-xhx9pzhj 4376 10 5/ 5/ CD cord-005646-xhx9pzhj 4376 11 ) ) -RRB- cord-005646-xhx9pzhj 4377 1 mg mg NNP cord-005646-xhx9pzhj 4377 2 for for IN cord-005646-xhx9pzhj 4377 3 1 1 CD cord-005646-xhx9pzhj 4377 4 mt mt NNP cord-005646-xhx9pzhj 4377 5 vial vial NN cord-005646-xhx9pzhj 4378 1 > > XX cord-005646-xhx9pzhj 4379 1 10 10 CD cord-005646-xhx9pzhj 4379 2 % % NN cord-005646-xhx9pzhj 4379 3 do do VBP cord-005646-xhx9pzhj 4379 4 ~ ~ NFP cord-005646-xhx9pzhj 4379 5 ge ge NNP cord-005646-xhx9pzhj 4379 6 , , , cord-005646-xhx9pzhj 4379 7 ermr~ ermr~ NNP cord-005646-xhx9pzhj 4379 8 were be VBD cord-005646-xhx9pzhj 4379 9 found find VBN cord-005646-xhx9pzhj 4379 10 in in IN cord-005646-xhx9pzhj 4379 11 19/40 19/40 CD cord-005646-xhx9pzhj 4379 12 cases case NNS cord-005646-xhx9pzhj 4379 13 ; ; : cord-005646-xhx9pzhj 4379 14 ~ ~ CD cord-005646-xhx9pzhj 4379 15 30 30 CD cord-005646-xhx9pzhj 4379 16 % % NN cord-005646-xhx9pzhj 4379 17 in in IN cord-005646-xhx9pzhj 4379 18 , , , cord-005646-xhx9pzhj 4379 19 t1,tO t1,to JJ cord-005646-xhx9pzhj 4379 20 cases case NNS cord-005646-xhx9pzhj 4379 21 . . . cord-005646-xhx9pzhj 4380 1 if if IN cord-005646-xhx9pzhj 4380 2 preparation preparation NN cord-005646-xhx9pzhj 4380 3 is be VBZ cord-005646-xhx9pzhj 4380 4 done do VBN cord-005646-xhx9pzhj 4380 5 from from IN cord-005646-xhx9pzhj 4380 6 Amikacine Amikacine NNP cord-005646-xhx9pzhj 4380 7 " " '' cord-005646-xhx9pzhj 4380 8 ~it'st ~it'st NNP cord-005646-xhx9pzhj 4380 9 SOltltion SOltltion NNP cord-005646-xhx9pzhj 4380 10 " " '' cord-005646-xhx9pzhj 4380 11 , , , cord-005646-xhx9pzhj 4380 12 les.--ConcenVr les.--ConcenVr NNP cord-005646-xhx9pzhj 4380 13 ~ ~ NFP cord-005646-xhx9pzhj 4380 14 tcd tcd NNP cord-005646-xhx9pzhj 4380 15 , , , cord-005646-xhx9pzhj 4381 1 it -PRON- PRP cord-005646-xhx9pzhj 4381 2 i~ i~ CD cord-005646-xhx9pzhj 4382 1 more more JJR cord-005646-xhx9pzhj 4382 2 preci,,,e preci,,,e NNS cord-005646-xhx9pzhj 4382 3 and and CC cord-005646-xhx9pzhj 4382 4 only only RB cord-005646-xhx9pzhj 4382 5 one one CD cord-005646-xhx9pzhj 4382 6 dosage dosage NN cord-005646-xhx9pzhj 4382 7 error error NN cord-005646-xhx9pzhj 4382 8 ~ ~ CD cord-005646-xhx9pzhj 4382 9 5 5 CD cord-005646-xhx9pzhj 4382 10 % % NN cord-005646-xhx9pzhj 4382 11 ( ( -LRB- cord-005646-xhx9pzhj 4382 12 6,3 6,3 CD cord-005646-xhx9pzhj 4382 13 % % NN cord-005646-xhx9pzhj 4382 14 } } -RRB- cord-005646-xhx9pzhj 4382 15 is be VBZ cord-005646-xhx9pzhj 4382 16 found find VBN cord-005646-xhx9pzhj 4382 17 in in IN cord-005646-xhx9pzhj 4382 18 eli eli NNP cord-005646-xhx9pzhj 4382 19 30 30 CD cord-005646-xhx9pzhj 4382 20 studied study VBD cord-005646-xhx9pzhj 4382 21 doses dose NNS cord-005646-xhx9pzhj 4382 22 . . . cord-005646-xhx9pzhj 4383 1 In in IN cord-005646-xhx9pzhj 4383 2 add)inn add)inn NNP cord-005646-xhx9pzhj 4383 3 to to IN cord-005646-xhx9pzhj 4383 4 ) ) -RRB- cord-005646-xhx9pzhj 4383 5 hal hal NNP cord-005646-xhx9pzhj 4383 6 if if IN cord-005646-xhx9pzhj 4383 7 10 10 CD cord-005646-xhx9pzhj 4383 8 doses dose NNS cord-005646-xhx9pzhj 4383 9 were be VBD cord-005646-xhx9pzhj 4383 10 wep wep NNP cord-005646-xhx9pzhj 4383 11 , , , cord-005646-xhx9pzhj 4383 12 m-'d m-'d CD cord-005646-xhx9pzhj 4383 13 from from IN cord-005646-xhx9pzhj 4383 14 one one CD cord-005646-xhx9pzhj 4383 15 " " `` cord-005646-xhx9pzhj 4383 16 first first JJ cord-005646-xhx9pzhj 4383 17 soiatiol~ soiatiol~ NNP cord-005646-xhx9pzhj 4383 18 ' ' '' cord-005646-xhx9pzhj 4383 19 bag bag NN cord-005646-xhx9pzhj 4383 20 , , , cord-005646-xhx9pzhj 4383 21 the the DT cord-005646-xhx9pzhj 4383 22 cost cost NN cord-005646-xhx9pzhj 4383 23 economy economy NN cord-005646-xhx9pzhj 4383 24 sl sl NN cord-005646-xhx9pzhj 4383 25 ~ ~ NFP cord-005646-xhx9pzhj 4383 26 ouid ouid NNP cord-005646-xhx9pzhj 4383 27 b~ b~ IN cord-005646-xhx9pzhj 4383 28 " " '' cord-005646-xhx9pzhj 4383 29 of of IN cord-005646-xhx9pzhj 4383 30 32 32 CD cord-005646-xhx9pzhj 4383 31 fr~ fr~ NN cord-005646-xhx9pzhj 4383 32 , , , cord-005646-xhx9pzhj 4383 33 and and CC cord-005646-xhx9pzhj 4383 34 ii ii NN cord-005646-xhx9pzhj 4383 35 20 20 CD cord-005646-xhx9pzhj 4383 36 dos~$ dos~$ NNS cord-005646-xhx9pzhj 4383 37 Were be VBD cord-005646-xhx9pzhj 4383 38 prepared prepared JJ cord-005646-xhx9pzhj 4383 39 tram tram NN cord-005646-xhx9pzhj 4383 40 the the DT cord-005646-xhx9pzhj 4383 41 same same JJ cord-005646-xhx9pzhj 4383 42 bag bag NN cord-005646-xhx9pzhj 4383 43 the the DT cord-005646-xhx9pzhj 4383 44 saving saving NN cord-005646-xhx9pzhj 4383 45 mtmey mtmey NNS cord-005646-xhx9pzhj 4383 46 should should MD cord-005646-xhx9pzhj 4383 47 be be VB cord-005646-xhx9pzhj 4383 48 o o NFP cord-005646-xhx9pzhj 4383 49 { { -LRB- cord-005646-xhx9pzhj 4383 50 I72 I72 NNP cord-005646-xhx9pzhj 4384 1 Its -PRON- PRP$ cord-005646-xhx9pzhj 4384 2 .Cencluslon .Cencluslon . cord-005646-xhx9pzhj 4385 1 : : : cord-005646-xhx9pzhj 4385 2 .ur .ur NFP cord-005646-xhx9pzhj 4385 3 survey survey NN cord-005646-xhx9pzhj 4385 4 shows show VBZ cord-005646-xhx9pzhj 4385 5 th th XX cord-005646-xhx9pzhj 4386 1 ~t ~t NNP cord-005646-xhx9pzhj 4386 2 h h NNP cord-005646-xhx9pzhj 4386 3 ' ' `` cord-005646-xhx9pzhj 4386 4 ntu)nato|ogy ntu)nato|ogy NN cord-005646-xhx9pzhj 4386 5 the the DT cord-005646-xhx9pzhj 4386 6 u~ u~ XX cord-005646-xhx9pzhj 4386 7 of of IN cord-005646-xhx9pzhj 4386 8 a a DT cord-005646-xhx9pzhj 4386 9 " " `` cord-005646-xhx9pzhj 4386 10 first first JJ cord-005646-xhx9pzhj 4386 11 sohation sohation NN cord-005646-xhx9pzhj 4386 12 which which WDT cord-005646-xhx9pzhj 4386 13 can can MD cord-005646-xhx9pzhj 4386 14 be be VB cord-005646-xhx9pzhj 4386 15 kept keep VBN cord-005646-xhx9pzhj 4386 16 fi fi XX cord-005646-xhx9pzhj 4387 1 ~r ~r NNP cord-005646-xhx9pzhj 4387 2 one one CD cord-005646-xhx9pzhj 4387 3 week week NN cord-005646-xhx9pzhj 4387 4 Is be VBZ cord-005646-xhx9pzhj 4387 5 enable enable VB cord-005646-xhx9pzhj 4387 6 to to TO cord-005646-xhx9pzhj 4387 7 reduce reduce VB cord-005646-xhx9pzhj 4387 8 dosage dosage NN cord-005646-xhx9pzhj 4387 9 erroes erroe NNS cord-005646-xhx9pzhj 4387 10 and and CC cord-005646-xhx9pzhj 4387 11 i~ i~ CD cord-005646-xhx9pzhj 4387 12 co,~tsavmg co,~tsavmg CD cord-005646-xhx9pzhj 4387 13 , , , cord-005646-xhx9pzhj 4387 14 Regarding regard VBG cord-005646-xhx9pzhj 4387 15 [ [ -LRB- cord-005646-xhx9pzhj 4387 16 , , , cord-005646-xhx9pzhj 4387 17 V. V. NNP cord-005646-xhx9pzhj 4387 18 admimst'rahon admimst'rahon NNP cord-005646-xhx9pzhj 4387 19 method method NN cord-005646-xhx9pzhj 4387 20 the the DT cord-005646-xhx9pzhj 4387 21 survey survey NN cord-005646-xhx9pzhj 4387 22 is be VBZ cord-005646-xhx9pzhj 4387 23 still still RB cord-005646-xhx9pzhj 4387 24 on on RB cord-005646-xhx9pzhj 4387 25 , , , cord-005646-xhx9pzhj 4387 26 INTRODUCTION introduction NN cord-005646-xhx9pzhj 4387 27 : : : cord-005646-xhx9pzhj 4387 28 So so RB cord-005646-xhx9pzhj 4387 29 - - HYPH cord-005646-xhx9pzhj 4387 30 called call VBN cord-005646-xhx9pzhj 4387 31 vein vein NN cord-005646-xhx9pzhj 4387 32 of of IN cord-005646-xhx9pzhj 4387 33 Galen Galen NNP cord-005646-xhx9pzhj 4387 34 m m NNP cord-005646-xhx9pzhj 4387 35 ~ ~ NFP cord-005646-xhx9pzhj 4387 36 Iformations Iformations NNP cord-005646-xhx9pzhj 4387 37 ale ale NN cord-005646-xhx9pzhj 4387 38 rare rare JJ cord-005646-xhx9pzhj 4387 39 in in IN cord-005646-xhx9pzhj 4387 40 ~ ~ NFP cord-005646-xhx9pzhj 4387 41 racranial racranial JJ cord-005646-xhx9pzhj 4387 42 embryologycal embryologycal JJ cord-005646-xhx9pzhj 4387 43 anomalies anomaly NNS cord-005646-xhx9pzhj 4387 44 , , , cord-005646-xhx9pzhj 4387 45 repl repl NNP cord-005646-xhx9pzhj 4387 46 ~ ~ NFP cord-005646-xhx9pzhj 4387 47 senti senti NNP cord-005646-xhx9pzhj 4387 48 ~ ~ NNP cord-005646-xhx9pzhj 4387 49 g g NNP cord-005646-xhx9pzhj 4387 50 tess tess NNP cord-005646-xhx9pzhj 4388 1 Than than IN cord-005646-xhx9pzhj 4388 2 1 1 CD cord-005646-xhx9pzhj 4388 3 of of IN cord-005646-xhx9pzhj 4388 4 symptomatic symptomatic JJ cord-005646-xhx9pzhj 4388 5 intracranied intracranied JJ cord-005646-xhx9pzhj 4388 6 artefiovenoas artefiovenoas NNP cord-005646-xhx9pzhj 4388 7 l l NNP cord-005646-xhx9pzhj 4388 8 ~ ~ NFP cord-005646-xhx9pzhj 4388 9 alform alform NNP cord-005646-xhx9pzhj 4388 10 ~ ~ NFP cord-005646-xhx9pzhj 4388 11 tions tion NNS cord-005646-xhx9pzhj 4388 12 . . . cord-005646-xhx9pzhj 4389 1 The the DT cord-005646-xhx9pzhj 4389 2 spontLneous spontlneous JJ cord-005646-xhx9pzhj 4389 3 prognosis prognosis NN cord-005646-xhx9pzhj 4389 4 is be VBZ cord-005646-xhx9pzhj 4390 1 ~s ~s NNP cord-005646-xhx9pzhj 4391 1 ~u ~u NNP cord-005646-xhx9pzhj 4391 2 ~ ~ NFP cord-005646-xhx9pzhj 4391 3 lly lly RB cord-005646-xhx9pzhj 4391 4 fatal fatal JJ cord-005646-xhx9pzhj 4391 5 , , , cord-005646-xhx9pzhj 4391 6 because because IN cord-005646-xhx9pzhj 4391 7 of of IN cord-005646-xhx9pzhj 4391 8 cardiac cardiac JJ cord-005646-xhx9pzhj 4391 9 fRilure fRilure NNP cord-005646-xhx9pzhj 4391 10 due due IN cord-005646-xhx9pzhj 4391 11 to to IN cord-005646-xhx9pzhj 4391 12 left leave VBN cord-005646-xhx9pzhj 4391 13 - - HYPH cord-005646-xhx9pzhj 4391 14 to to IN cord-005646-xhx9pzhj 4391 15 - - HYPH cord-005646-xhx9pzhj 4391 16 right right JJ cord-005646-xhx9pzhj 4391 17 shunt shunt NN cord-005646-xhx9pzhj 4391 18 thrQ thrq JJ cord-005646-xhx9pzhj 4392 1 ~ugh ~ugh VB cord-005646-xhx9pzhj 4392 2 the the DT cord-005646-xhx9pzhj 4392 3 fistula fistula NN cord-005646-xhx9pzhj 4392 4 . . . cord-005646-xhx9pzhj 4393 1 Recent recent JJ cord-005646-xhx9pzhj 4393 2 developments development NNS cord-005646-xhx9pzhj 4393 3 of of IN cord-005646-xhx9pzhj 4393 4 new new JJ cord-005646-xhx9pzhj 4393 5 techniques technique NNS cord-005646-xhx9pzhj 4393 6 of of IN cord-005646-xhx9pzhj 4393 7 treatment treatment NN cord-005646-xhx9pzhj 4393 8 of of IN cord-005646-xhx9pzhj 4393 9 the the DT cord-005646-xhx9pzhj 4393 10 malformation malformation NN cord-005646-xhx9pzhj 4393 11 and and CC cord-005646-xhx9pzhj 4393 12 its -PRON- PRP$ cord-005646-xhx9pzhj 4393 13 cardiac cardiac JJ cord-005646-xhx9pzhj 4393 14 consequence consequence NN cord-005646-xhx9pzhj 4393 15 have have VBP cord-005646-xhx9pzhj 4393 16 led lead VBN cord-005646-xhx9pzhj 4393 17 to to IN cord-005646-xhx9pzhj 4393 18 a a DT cord-005646-xhx9pzhj 4393 19 revolution revolution NN cord-005646-xhx9pzhj 4393 20 in in IN cord-005646-xhx9pzhj 4393 21 the the DT cord-005646-xhx9pzhj 4393 22 practical practical JJ cord-005646-xhx9pzhj 4393 23 approach approach NN cord-005646-xhx9pzhj 4393 24 of of IN cord-005646-xhx9pzhj 4393 25 children child NNS cord-005646-xhx9pzhj 4393 26 w w IN cord-005646-xhx9pzhj 4393 27 ~ ~ NFP cord-005646-xhx9pzhj 4393 28 th th XX cord-005646-xhx9pzhj 4393 29 Galen Galen NNP cord-005646-xhx9pzhj 4393 30 malformation malformation NN cord-005646-xhx9pzhj 4393 31 . . . cord-005646-xhx9pzhj 4394 1 OUR our PRP$ cord-005646-xhx9pzhj 4394 2 FUKFOSE FUKFOSE NNP cord-005646-xhx9pzhj 4394 3 is be VBZ cord-005646-xhx9pzhj 4394 4 to to TO cord-005646-xhx9pzhj 4394 5 contribute contribute VB cord-005646-xhx9pzhj 4394 6 , , , cord-005646-xhx9pzhj 4394 7 with with IN cord-005646-xhx9pzhj 4394 8 our -PRON- PRP$ cord-005646-xhx9pzhj 4394 9 persoaal persoaal NNP cord-005646-xhx9pzhj 4394 10 series series NN cord-005646-xhx9pzhj 4394 11 of of IN cord-005646-xhx9pzhj 4394 12 7S 7S NNP cord-005646-xhx9pzhj 4394 13 newborns newborns NNPS cord-005646-xhx9pzhj 4394 14 and and CC cord-005646-xhx9pzhj 4394 15 infal infal NNP cord-005646-xhx9pzhj 4394 16 ~ ~ NFP cord-005646-xhx9pzhj 4394 17 ts ts NNP cord-005646-xhx9pzhj 4394 18 admitted admit VBD cord-005646-xhx9pzhj 4394 19 in in IN cord-005646-xhx9pzhj 4394 20 our -PRON- PRP$ cord-005646-xhx9pzhj 4394 21 unit unit NN cord-005646-xhx9pzhj 4394 22 after after IN cord-005646-xhx9pzhj 4394 23 endov~,scular endov~,scular JJ cord-005646-xhx9pzhj 4394 24 embolization embolization NN cord-005646-xhx9pzhj 4394 25 , , , cord-005646-xhx9pzhj 4394 26 to to IN cord-005646-xhx9pzhj 4394 27 a a DT cord-005646-xhx9pzhj 4394 28 better well JJR cord-005646-xhx9pzhj 4394 29 management management NN cord-005646-xhx9pzhj 4394 30 of of IN cord-005646-xhx9pzhj 4394 31 these these DT cord-005646-xhx9pzhj 4394 32 children child NNS cord-005646-xhx9pzhj 4394 33 . . . cord-005646-xhx9pzhj 4395 1 Such such JJ cord-005646-xhx9pzhj 4395 2 a a DT cord-005646-xhx9pzhj 4395 3 management management NN cord-005646-xhx9pzhj 4395 4 requ!res requ!re VBZ cord-005646-xhx9pzhj 4395 5 a a DT cord-005646-xhx9pzhj 4395 6 rnultidisciplinary rnultidisciplinary JJ cord-005646-xhx9pzhj 4395 7 approach approach NN cord-005646-xhx9pzhj 4395 8 . . . cord-005646-xhx9pzhj 4396 1 Intensive intensive JJ cord-005646-xhx9pzhj 4396 2 care care NN cord-005646-xhx9pzhj 4396 3 are be VBP cord-005646-xhx9pzhj 4396 4 required require VBN cord-005646-xhx9pzhj 4396 5 prior prior RB cord-005646-xhx9pzhj 4396 6 to to IN cord-005646-xhx9pzhj 4396 7 embollzation embollzation NN cord-005646-xhx9pzhj 4396 8 for for IN cord-005646-xhx9pzhj 4396 9 patients patient NNS cord-005646-xhx9pzhj 4396 10 with with IN cord-005646-xhx9pzhj 4396 11 cardiac cardiac JJ cord-005646-xhx9pzhj 4396 12 failure failure NN cord-005646-xhx9pzhj 4396 13 or or CC cord-005646-xhx9pzhj 4396 14 cardiogenic cardiogenic JJ cord-005646-xhx9pzhj 4396 15 shock shock NN cord-005646-xhx9pzhj 4396 16 and and CC cord-005646-xhx9pzhj 4396 17 after after IN cord-005646-xhx9pzhj 4396 18 cmbolization cmbolization NN cord-005646-xhx9pzhj 4396 19 in in IN cord-005646-xhx9pzhj 4396 20 order order NN cord-005646-xhx9pzhj 4396 21 to to TO cord-005646-xhx9pzhj 4396 22 insure insure VB cord-005646-xhx9pzhj 4396 23 cardiac cardiac JJ cord-005646-xhx9pzhj 4396 24 and and CC cord-005646-xhx9pzhj 4396 25 cerebral cerebral JJ cord-005646-xhx9pzhj 4396 26 hemodyna.mic hemodyna.mic NNP cord-005646-xhx9pzhj 4396 27 stabilities stability NNS cord-005646-xhx9pzhj 4396 28 . . . cord-005646-xhx9pzhj 4397 1 This this DT cord-005646-xhx9pzhj 4397 2 overlooking overlooking NN cord-005646-xhx9pzhj 4397 3 suppose suppose NN cord-005646-xhx9pzhj 4397 4 for for IN cord-005646-xhx9pzhj 4397 5 the the DT cord-005646-xhx9pzhj 4397 6 nursing nursing NN cord-005646-xhx9pzhj 4397 7 team team NN cord-005646-xhx9pzhj 4397 8 to to TO cord-005646-xhx9pzhj 4397 9 understand understand VB cord-005646-xhx9pzhj 4397 10 : : : cord-005646-xhx9pzhj 4397 11 prior prior RB cord-005646-xhx9pzhj 4397 12 to to IN cord-005646-xhx9pzhj 4397 13 embolization embolization NN cord-005646-xhx9pzhj 4397 14 : : : cord-005646-xhx9pzhj 4397 15 heart heart NN cord-005646-xhx9pzhj 4397 16 failure failure NN cord-005646-xhx9pzhj 4397 17 and and CC cord-005646-xhx9pzhj 4397 18 cardiogenic cardiogenic JJ cord-005646-xhx9pzhj 4397 19 shock shock NN cord-005646-xhx9pzhj 4397 20 . . . cord-005646-xhx9pzhj 4398 1 after after IN cord-005646-xhx9pzhj 4398 2 cmbolization cmbolization NN cord-005646-xhx9pzhj 4398 3 : : : cord-005646-xhx9pzhj 4398 4 evaluation evaluation NN cord-005646-xhx9pzhj 4398 5 of of IN cord-005646-xhx9pzhj 4398 6 neurological neurological JJ cord-005646-xhx9pzhj 4398 7 and and CC cord-005646-xhx9pzhj 4398 8 hemodynamic hemodynamic JJ cord-005646-xhx9pzhj 4398 9 consequences consequence NNS cord-005646-xhx9pzhj 4398 10 of of IN cord-005646-xhx9pzhj 4398 11 this this DT cord-005646-xhx9pzhj 4398 12 proccdure proccdure NN cord-005646-xhx9pzhj 4398 13 , , , cord-005646-xhx9pzhj 4398 14 without without IN cord-005646-xhx9pzhj 4398 15 forgetting forget VBG cord-005646-xhx9pzhj 4398 16 the the DT cord-005646-xhx9pzhj 4398 17 nursing nursing NN cord-005646-xhx9pzhj 4398 18 and and CC cord-005646-xhx9pzhj 4398 19 psychologic psychologic JJ cord-005646-xhx9pzhj 4398 20 aspects aspect NNS cord-005646-xhx9pzhj 4398 21 , , , cord-005646-xhx9pzhj 4398 22 IN in IN cord-005646-xhx9pzhj 4398 23 CONCL'IISION concl'iision NN cord-005646-xhx9pzhj 4398 24 , , , cord-005646-xhx9pzhj 4398 25 this this DT cord-005646-xhx9pzhj 4398 26 last last JJ cord-005646-xhx9pzhj 4398 27 ten ten NN cord-005646-xhx9pzhj 4398 28 yeRrs yerrs NN cord-005646-xhx9pzhj 4398 29 , , , cord-005646-xhx9pzhj 4398 30 these these DT cord-005646-xhx9pzhj 4398 31 new new JJ cord-005646-xhx9pzhj 4398 32 approaches approach NNS cord-005646-xhx9pzhj 4398 33 give give VBP cord-005646-xhx9pzhj 4398 34 to to IN cord-005646-xhx9pzhj 4398 35 the the DT cord-005646-xhx9pzhj 4398 36 patients patient NNS cord-005646-xhx9pzhj 4398 37 and and CC cord-005646-xhx9pzhj 4398 38 their -PRON- PRP$ cord-005646-xhx9pzhj 4398 39 famitiy famitiy NNS cord-005646-xhx9pzhj 4398 40 a a DT cord-005646-xhx9pzhj 4398 41 good good JJ cord-005646-xhx9pzhj 4398 42 reason reason NN cord-005646-xhx9pzhj 4398 43 to to TO cord-005646-xhx9pzhj 4398 44 hope hope VB cord-005646-xhx9pzhj 4398 45 a a DT cord-005646-xhx9pzhj 4398 46 total total JJ cord-005646-xhx9pzhj 4398 47 recovew recovew NN cord-005646-xhx9pzhj 4398 48 , , , cord-005646-xhx9pzhj 4398 49 In in IN cord-005646-xhx9pzhj 4398 50 our -PRON- PRP$ cord-005646-xhx9pzhj 4398 51 exl)erience exl)erience NN cord-005646-xhx9pzhj 4398 52 , , , cord-005646-xhx9pzhj 4398 53 the the DT cord-005646-xhx9pzhj 4398 54 global global JJ cord-005646-xhx9pzhj 4398 55 mortality mortality NN cord-005646-xhx9pzhj 4398 56 is be VBZ cord-005646-xhx9pzhj 4398 57 9 9 CD cord-005646-xhx9pzhj 4398 58 % % NN cord-005646-xhx9pzhj 4398 59 aad aad NNP cord-005646-xhx9pzhj 4398 60 66 66 CD cord-005646-xhx9pzhj 4398 61 % % NN cord-005646-xhx9pzhj 4398 62 of of IN cord-005646-xhx9pzhj 4398 63 children child NNS cord-005646-xhx9pzhj 4398 64 # # $ cord-005646-xhx9pzhj 4398 65 j j NNP cord-005646-xhx9pzhj 4398 66 - - HYPH cord-005646-xhx9pzhj 4398 67 e e LS cord-005646-xhx9pzhj 4398 68 neurologically neurologically RB cord-005646-xhx9pzhj 4398 69 normal normal JJ cord-005646-xhx9pzhj 4398 70 after after IN cord-005646-xhx9pzhj 4398 71 embolizafion embolizafion NN cord-005646-xhx9pzhj 4399 1 , , , cord-005646-xhx9pzhj 4399 2 ii ii NNP cord-005646-xhx9pzhj 4399 3 ii~ ii~ NNP cord-005646-xhx9pzhj 4400 1 i i PRP cord-005646-xhx9pzhj 4401 1 ~ii ~ii NNP cord-005646-xhx9pzhj 4402 1 i i PRP cord-005646-xhx9pzhj 4403 1 ii ii LS cord-005646-xhx9pzhj 4404 1 i i PRP cord-005646-xhx9pzhj 4405 1 i i PRP cord-005646-xhx9pzhj 4406 1 L L NNP cord-005646-xhx9pzhj 4407 1 i i PRP cord-005646-xhx9pzhj 4408 1 iiii~ iiii~ NNP cord-005646-xhx9pzhj 4409 1 i i PRP cord-005646-xhx9pzhj 4410 1 ~i ~i NNP cord-005646-xhx9pzhj 4411 1 iii iii NNP cord-005646-xhx9pzhj 4412 1 i i PRP cord-005646-xhx9pzhj 4412 2 Background Background NNP cord-005646-xhx9pzhj 4412 3 : : : cord-005646-xhx9pzhj 4413 1 Venous venous JJ cord-005646-xhx9pzhj 4413 2 oxygen oxygen NN cord-005646-xhx9pzhj 4413 3 saturation saturation NN cord-005646-xhx9pzhj 4413 4 ( ( -LRB- cord-005646-xhx9pzhj 4413 5 SvO SvO NNP cord-005646-xhx9pzhj 4413 6 z z NNP cord-005646-xhx9pzhj 4413 7 ) ) -RRB- cord-005646-xhx9pzhj 4413 8 reflects reflect VBZ cord-005646-xhx9pzhj 4413 9 the the DT cord-005646-xhx9pzhj 4413 10 residuaI residuaI NNP cord-005646-xhx9pzhj 4413 11 oxygen oxygen NN cord-005646-xhx9pzhj 4413 12 after after IN cord-005646-xhx9pzhj 4413 13 tissue tissue NN cord-005646-xhx9pzhj 4413 14 oxygen oxygen NN cord-005646-xhx9pzhj 4413 15 extraction extraction NN cord-005646-xhx9pzhj 4413 16 and and CC cord-005646-xhx9pzhj 4413 17 represents represent VBZ cord-005646-xhx9pzhj 4413 18 the the DT cord-005646-xhx9pzhj 4413 19 relation relation NN cord-005646-xhx9pzhj 4413 20 between between IN cord-005646-xhx9pzhj 4413 21 tissue tissue NN cord-005646-xhx9pzhj 4413 22 oxygen oxygen NN cord-005646-xhx9pzhj 4413 23 supply supply NN cord-005646-xhx9pzhj 4413 24 and and CC cord-005646-xhx9pzhj 4413 25 demand demand NN cord-005646-xhx9pzhj 4413 26 . . . cord-005646-xhx9pzhj 4414 1 We -PRON- PRP cord-005646-xhx9pzhj 4414 2 studied study VBD cord-005646-xhx9pzhj 4414 3 SvO SvO NNP cord-005646-xhx9pzhj 4414 4 2 2 CD cord-005646-xhx9pzhj 4414 5 and and CC cord-005646-xhx9pzhj 4414 6 arterial arterial JJ cord-005646-xhx9pzhj 4414 7 lactate lactate NN cord-005646-xhx9pzhj 4414 8 during during IN cord-005646-xhx9pzhj 4414 9 progressive progressive JJ cord-005646-xhx9pzhj 4414 10 isovolemic isovolemic JJ cord-005646-xhx9pzhj 4414 11 anemia anemia NN cord-005646-xhx9pzhj 4414 12 to to TO cord-005646-xhx9pzhj 4414 13 assess assess VB cord-005646-xhx9pzhj 4414 14 the the DT cord-005646-xhx9pzhj 4414 15 relation relation NN cord-005646-xhx9pzhj 4414 16 between between IN cord-005646-xhx9pzhj 4414 17 SvO2 SvO2 NNS cord-005646-xhx9pzhj 4414 18 and and CC cord-005646-xhx9pzhj 4414 19 tissue tissue NN cord-005646-xhx9pzhj 4414 20 hypoxia hypoxia NN cord-005646-xhx9pzhj 4414 21 . . . cord-005646-xhx9pzhj 4415 1 Subjects subject NNS cord-005646-xhx9pzhj 4415 2 : : : cord-005646-xhx9pzhj 4416 1 Ten ten CD cord-005646-xhx9pzhj 4416 2 8 8 CD cord-005646-xhx9pzhj 4416 3 - - SYM cord-005646-xhx9pzhj 4416 4 10 10 CD cord-005646-xhx9pzhj 4416 5 day day NN cord-005646-xhx9pzhj 4416 6 old old JJ cord-005646-xhx9pzhj 4416 7 anesthetized anesthetize VBN cord-005646-xhx9pzhj 4416 8 ventilated ventilate VBN cord-005646-xhx9pzhj 4416 9 piglets piglet NNS cord-005646-xhx9pzhj 4416 10 SaO SaO NNP cord-005646-xhx9pzhj 4416 11 2 2 CD cord-005646-xhx9pzhj 4416 12 and and CC cord-005646-xhx9pzhj 4416 13 SvQ svq NN cord-005646-xhx9pzhj 4416 14 were be VBD cord-005646-xhx9pzhj 4416 15 measured measure VBN cord-005646-xhx9pzhj 4416 16 continuously continuously RB cord-005646-xhx9pzhj 4416 17 by by IN cord-005646-xhx9pzhj 4416 18 a a DT cord-005646-xhx9pzhj 4416 19 fiberoptic fiberoptic JJ cord-005646-xhx9pzhj 4416 20 catheter catheter NN cord-005646-xhx9pzhj 4416 21 ( ( -LRB- cord-005646-xhx9pzhj 4416 22 Oximetrix Oximetrix NNP cord-005646-xhx9pzhj 4416 23 , , , cord-005646-xhx9pzhj 4416 24 Abbott Abbott NNP cord-005646-xhx9pzhj 4416 25 Lab Lab NNP cord-005646-xhx9pzhj 4416 26 . . . cord-005646-xhx9pzhj 4416 27 ) ) -RRB- cord-005646-xhx9pzhj 4417 1 in in IN cord-005646-xhx9pzhj 4417 2 the the DT cord-005646-xhx9pzhj 4417 3 carotid carotid JJ cord-005646-xhx9pzhj 4417 4 and and CC cord-005646-xhx9pzhj 4417 5 pulmonary pulmonary NN cord-005646-xhx9pzhj 4417 6 a a DT cord-005646-xhx9pzhj 4417 7 ~ ~ NFP cord-005646-xhx9pzhj 4417 8 epy epy NNP cord-005646-xhx9pzhj 4417 9 Tissue tissue NN cord-005646-xhx9pzhj 4417 10 hypoxia hypoxia NN cord-005646-xhx9pzhj 4417 11 was be VBD cord-005646-xhx9pzhj 4417 12 confirmed confirm VBN cord-005646-xhx9pzhj 4417 13 by by IN cord-005646-xhx9pzhj 4417 14 a a DT cord-005646-xhx9pzhj 4417 15 reduced reduce VBN cord-005646-xhx9pzhj 4417 16 VO VO NNP cord-005646-xhx9pzhj 4417 17 , , , cord-005646-xhx9pzhj 4417 18 and and CC cord-005646-xhx9pzhj 4417 19 an an DT cord-005646-xhx9pzhj 4417 20 increase increase NN cord-005646-xhx9pzhj 4417 21 in in IN cord-005646-xhx9pzhj 4417 22 lactate lactate NN cord-005646-xhx9pzhj 4417 23 . . . cord-005646-xhx9pzhj 4418 1 Conclusion conclusion NN cord-005646-xhx9pzhj 4418 2 : : : cord-005646-xhx9pzhj 4419 1 SvO SvO NNP cord-005646-xhx9pzhj 4419 2 2 2 CD cord-005646-xhx9pzhj 4419 3 reflects reflect VBZ cord-005646-xhx9pzhj 4419 4 better well JJR cord-005646-xhx9pzhj 4420 1 a a DT cord-005646-xhx9pzhj 4420 2 reduced reduce VBN cord-005646-xhx9pzhj 4420 3 Dp Dp NNP cord-005646-xhx9pzhj 4420 4 obtained obtain VBN cord-005646-xhx9pzhj 4420 5 by by IN cord-005646-xhx9pzhj 4420 6 progressive progressive JJ cord-005646-xhx9pzhj 4420 7 anemia anemia NN cord-005646-xhx9pzhj 4420 8 Surfactant Surfactant NNP cord-005646-xhx9pzhj 4420 9 replacement replacement NN cord-005646-xhx9pzhj 4420 10 improves improve VBZ cord-005646-xhx9pzhj 4420 11 gas gas NN cord-005646-xhx9pzhj 4420 12 exchange exchange NN cord-005646-xhx9pzhj 4420 13 in in IN cord-005646-xhx9pzhj 4420 14 early early JJ cord-005646-xhx9pzhj 4420 15 - - HYPH cord-005646-xhx9pzhj 4420 16 stage stage NN cord-005646-xhx9pzhj 4420 17 adult adult NN cord-005646-xhx9pzhj 4420 18 respiratory respiratory JJ cord-005646-xhx9pzhj 4420 19 syndrome syndrome NN cord-005646-xhx9pzhj 4420 20 ( ( -LRB- cord-005646-xhx9pzhj 4420 21 ARDS ARDS NNP cord-005646-xhx9pzhj 4420 22 ) ) -RRB- cord-005646-xhx9pzhj 4420 23 [ [ -LRB- cord-005646-xhx9pzhj 4420 24 1,2 1,2 CD cord-005646-xhx9pzhj 4420 25 ] ] -RRB- cord-005646-xhx9pzhj 4420 26 , , , cord-005646-xhx9pzhj 4420 27 but but CC cord-005646-xhx9pzhj 4420 28 not not RB cord-005646-xhx9pzhj 4420 29 in in IN cord-005646-xhx9pzhj 4420 30 late late JJ cord-005646-xhx9pzhj 4420 31 - - HYPH cord-005646-xhx9pzhj 4420 32 stage stage NN cord-005646-xhx9pzhj 4420 33 ARDS ARDS NNP cord-005646-xhx9pzhj 4420 34 [ [ -LRB- cord-005646-xhx9pzhj 4420 35 3 3 CD cord-005646-xhx9pzhj 4420 36 ] ] -RRB- cord-005646-xhx9pzhj 4420 37 . . . cord-005646-xhx9pzhj 4421 1 We -PRON- PRP cord-005646-xhx9pzhj 4421 2 report report VBP cord-005646-xhx9pzhj 4421 3 the the DT cord-005646-xhx9pzhj 4421 4 first first JJ cord-005646-xhx9pzhj 4421 5 case case NN cord-005646-xhx9pzhj 4421 6 of of IN cord-005646-xhx9pzhj 4421 7 successfull successfull JJ cord-005646-xhx9pzhj 4421 8 treatment treatment NN cord-005646-xhx9pzhj 4421 9 of of IN cord-005646-xhx9pzhj 4421 10 ARDS ARDS NNP cord-005646-xhx9pzhj 4421 11 after after IN cord-005646-xhx9pzhj 4421 12 repeated repeat VBN cord-005646-xhx9pzhj 4421 13 instillation instillation NN cord-005646-xhx9pzhj 4421 14 of of IN cord-005646-xhx9pzhj 4421 15 surfactant surfactant NN cord-005646-xhx9pzhj 4421 16 . . . cord-005646-xhx9pzhj 4422 1 A a DT cord-005646-xhx9pzhj 4422 2 ten ten CD cord-005646-xhx9pzhj 4422 3 year year NN cord-005646-xhx9pzhj 4422 4 old old JJ cord-005646-xhx9pzhj 4422 5 boy boy NN cord-005646-xhx9pzhj 4422 6 , , , cord-005646-xhx9pzhj 4422 7 weighing weigh VBG cord-005646-xhx9pzhj 4422 8 32 32 CD cord-005646-xhx9pzhj 4422 9 kg kg NNS cord-005646-xhx9pzhj 4422 10 , , , cord-005646-xhx9pzhj 4422 11 presented present VBN cord-005646-xhx9pzhj 4422 12 with with IN cord-005646-xhx9pzhj 4422 13 hemorragic hemorragic NNP cord-005646-xhx9pzhj 4422 14 shock shock NN cord-005646-xhx9pzhj 4422 15 . . . cord-005646-xhx9pzhj 4423 1 Biphasic Biphasic NNP cord-005646-xhx9pzhj 4423 2 - - HYPH cord-005646-xhx9pzhj 4423 3 Positive Positive NNP cord-005646-xhx9pzhj 4423 4 - - HYPH cord-005646-xhx9pzhj 4423 5 Airways Airways NNP cord-005646-xhx9pzhj 4423 6 - - HYPH cord-005646-xhx9pzhj 4423 7 Pressure Pressure NNP cord-005646-xhx9pzhj 4423 8 ventilation ventilation NN cord-005646-xhx9pzhj 4423 9 was be VBD cord-005646-xhx9pzhj 4423 10 performed perform VBN cord-005646-xhx9pzhj 4423 11 ( ( -LRB- cord-005646-xhx9pzhj 4423 12 Evita Evita NNP cord-005646-xhx9pzhj 4423 13 II II NNP cord-005646-xhx9pzhj 4423 14 , , , cord-005646-xhx9pzhj 4423 15 Dr Dr NNP cord-005646-xhx9pzhj 4423 16 ~ ~ NNP cord-005646-xhx9pzhj 4423 17 ger ger NNP cord-005646-xhx9pzhj 4423 18 , , , cord-005646-xhx9pzhj 4423 19 Germany Germany NNP cord-005646-xhx9pzhj 4423 20 ) ) -RRB- cord-005646-xhx9pzhj 4423 21 . . . cord-005646-xhx9pzhj 4424 1 He -PRON- PRP cord-005646-xhx9pzhj 4424 2 had have VBD cord-005646-xhx9pzhj 4424 3 recieved recieve VBN cord-005646-xhx9pzhj 4424 4 nine nine CD cord-005646-xhx9pzhj 4424 5 units unit NNS cord-005646-xhx9pzhj 4424 6 of of IN cord-005646-xhx9pzhj 4424 7 packed packed JJ cord-005646-xhx9pzhj 4424 8 red red JJ cord-005646-xhx9pzhj 4424 9 blood blood NN cord-005646-xhx9pzhj 4424 10 cells cell NNS cord-005646-xhx9pzhj 4424 11 and and CC cord-005646-xhx9pzhj 4424 12 underwent undergo VBD cord-005646-xhx9pzhj 4424 13 surgical surgical JJ cord-005646-xhx9pzhj 4424 14 exeresis exeresis NN cord-005646-xhx9pzhj 4424 15 of of IN cord-005646-xhx9pzhj 4424 16 two two CD cord-005646-xhx9pzhj 4424 17 bleeding bleed VBG cord-005646-xhx9pzhj 4424 18 gastric gastric JJ cord-005646-xhx9pzhj 4424 19 ulcus ulcus NN cord-005646-xhx9pzhj 4424 20 . . . cord-005646-xhx9pzhj 4425 1 Post post VB cord-005646-xhx9pzhj 4425 2 - - JJ cord-005646-xhx9pzhj 4425 3 operatively operatively RB cord-005646-xhx9pzhj 4425 4 , , , cord-005646-xhx9pzhj 4425 5 a a DT cord-005646-xhx9pzhj 4425 6 cardiac cardiac JJ cord-005646-xhx9pzhj 4425 7 arrest arrest NN cord-005646-xhx9pzhj 4425 8 required require VBN cord-005646-xhx9pzhj 4425 9 cardiopulmonary cardiopulmonary JJ cord-005646-xhx9pzhj 4425 10 resuscitation resuscitation NN cord-005646-xhx9pzhj 4425 11 for for IN cord-005646-xhx9pzhj 4425 12 three three CD cord-005646-xhx9pzhj 4425 13 minutes minute NNS cord-005646-xhx9pzhj 4425 14 . . . cord-005646-xhx9pzhj 4426 1 Hemodynamic Hemodynamic NNP cord-005646-xhx9pzhj 4426 2 status status NN cord-005646-xhx9pzhj 4426 3 was be VBD cord-005646-xhx9pzhj 4426 4 subsequently subsequently RB cord-005646-xhx9pzhj 4426 5 stabilised stabilise VBN cord-005646-xhx9pzhj 4426 6 . . . cord-005646-xhx9pzhj 4427 1 The the DT cord-005646-xhx9pzhj 4427 2 chest chest NN cord-005646-xhx9pzhj 4427 3 - - HYPH cord-005646-xhx9pzhj 4427 4 radiograph radiograph NN cord-005646-xhx9pzhj 4427 5 showed show VBD cord-005646-xhx9pzhj 4427 6 infiltrates infiltrate VBZ cord-005646-xhx9pzhj 4427 7 of of IN cord-005646-xhx9pzhj 4427 8 both both DT cord-005646-xhx9pzhj 4427 9 lungs lung NNS cord-005646-xhx9pzhj 4427 10 without without IN cord-005646-xhx9pzhj 4427 11 signs sign NNS cord-005646-xhx9pzhj 4427 12 of of IN cord-005646-xhx9pzhj 4427 13 cardiac cardiac JJ cord-005646-xhx9pzhj 4427 14 failure failure NN cord-005646-xhx9pzhj 4427 15 . . . cord-005646-xhx9pzhj 4428 1 On on IN cord-005646-xhx9pzhj 4428 2 the the DT cord-005646-xhx9pzhj 4428 3 third third JJ cord-005646-xhx9pzhj 4428 4 day day NN cord-005646-xhx9pzhj 4428 5 , , , cord-005646-xhx9pzhj 4428 6 the the DT cord-005646-xhx9pzhj 4428 7 patient patient NN cord-005646-xhx9pzhj 4428 8 became become VBD cord-005646-xhx9pzhj 4428 9 severely severely RB cord-005646-xhx9pzhj 4428 10 hypoxic hypoxic JJ cord-005646-xhx9pzhj 4428 11 with with IN cord-005646-xhx9pzhj 4428 12 a a DT cord-005646-xhx9pzhj 4428 13 PaO2 PaO2 NNS cord-005646-xhx9pzhj 4428 14 / / SYM cord-005646-xhx9pzhj 4428 15 FiO fio NN cord-005646-xhx9pzhj 4428 16 2 2 CD cord-005646-xhx9pzhj 4428 17 ratio ratio NN cord-005646-xhx9pzhj 4428 18 of of IN cord-005646-xhx9pzhj 4428 19 30 30 CD cord-005646-xhx9pzhj 4428 20 . . . cord-005646-xhx9pzhj 4429 1 Gas gas NN cord-005646-xhx9pzhj 4429 2 exchange exchange NN cord-005646-xhx9pzhj 4429 3 was be VBD cord-005646-xhx9pzhj 4429 4 not not RB cord-005646-xhx9pzhj 4429 5 improved improve VBN cord-005646-xhx9pzhj 4429 6 by by IN cord-005646-xhx9pzhj 4429 7 high high JJ cord-005646-xhx9pzhj 4429 8 ventilator ventilator NN cord-005646-xhx9pzhj 4429 9 settings setting NNS cord-005646-xhx9pzhj 4429 10 . . . cord-005646-xhx9pzhj 4430 1 Peak peak JJ cord-005646-xhx9pzhj 4430 2 inspiratory inspiratory JJ cord-005646-xhx9pzhj 4430 3 pressure pressure NN cord-005646-xhx9pzhj 4430 4 ( ( -LRB- cord-005646-xhx9pzhj 4430 5 PIP PIP NNP cord-005646-xhx9pzhj 4430 6 ) ) -RRB- cord-005646-xhx9pzhj 4430 7 and and CC cord-005646-xhx9pzhj 4430 8 ventilatory ventilatory JJ cord-005646-xhx9pzhj 4430 9 rates rate NNS cord-005646-xhx9pzhj 4430 10 were be VBD cord-005646-xhx9pzhj 4430 11 40 40 CD cord-005646-xhx9pzhj 4430 12 cmH cmh NN cord-005646-xhx9pzhj 4431 1 ~O ~o JJ cord-005646-xhx9pzhj 4431 2 and and CC cord-005646-xhx9pzhj 4431 3 18 18 CD cord-005646-xhx9pzhj 4431 4 breaths breath NNS cord-005646-xhx9pzhj 4431 5 / / SYM cord-005646-xhx9pzhj 4431 6 min min NN cord-005646-xhx9pzhj 4431 7 respectively respectively RB cord-005646-xhx9pzhj 4431 8 . . . cord-005646-xhx9pzhj 4432 1 Inspiratory Inspiratory NNP cord-005646-xhx9pzhj 4432 2 : : : cord-005646-xhx9pzhj 4432 3 expiratory expiratory JJ cord-005646-xhx9pzhj 4432 4 time time NN cord-005646-xhx9pzhj 4432 5 was be VBD cord-005646-xhx9pzhj 4432 6 1:1 1:1 CD cord-005646-xhx9pzhj 4432 7 and and CC cord-005646-xhx9pzhj 4432 8 the the DT cord-005646-xhx9pzhj 4432 9 positive positive JJ cord-005646-xhx9pzhj 4432 10 end end NN cord-005646-xhx9pzhj 4432 11 expiratory expiratory JJ cord-005646-xhx9pzhj 4432 12 pressure pressure NN cord-005646-xhx9pzhj 4432 13 ( ( -LRB- cord-005646-xhx9pzhj 4432 14 PEEP peep NN cord-005646-xhx9pzhj 4432 15 ) ) -RRB- cord-005646-xhx9pzhj 4432 16 8 8 CD cord-005646-xhx9pzhj 4432 17 cmH20 cmH20 NNP cord-005646-xhx9pzhj 4432 18 . . . cord-005646-xhx9pzhj 4433 1 After after IN cord-005646-xhx9pzhj 4433 2 increasing increase VBG cord-005646-xhx9pzhj 4433 3 the the DT cord-005646-xhx9pzhj 4433 4 PEEP peep NN cord-005646-xhx9pzhj 4433 5 level level NN cord-005646-xhx9pzhj 4433 6 to to IN cord-005646-xhx9pzhj 4433 7 11 11 CD cord-005646-xhx9pzhj 4433 8 cmH20 cmH20 NNP cord-005646-xhx9pzhj 4433 9 , , , cord-005646-xhx9pzhj 4433 10 we -PRON- PRP cord-005646-xhx9pzhj 4433 11 instilled instill VBD cord-005646-xhx9pzhj 4433 12 over over IN cord-005646-xhx9pzhj 4433 13 2 2 CD cord-005646-xhx9pzhj 4433 14 minutes minute NNS cord-005646-xhx9pzhj 4433 15 , , , cord-005646-xhx9pzhj 4433 16 80 80 CD cord-005646-xhx9pzhj 4433 17 mg mg NNP cord-005646-xhx9pzhj 4433 18 / / SYM cord-005646-xhx9pzhj 4433 19 kg kg NNS cord-005646-xhx9pzhj 4433 20 of of IN cord-005646-xhx9pzhj 4433 21 porcine porcine JJ cord-005646-xhx9pzhj 4433 22 surfactant surfactant NN cord-005646-xhx9pzhj 4433 23 ( ( -LRB- cord-005646-xhx9pzhj 4433 24 Curosurf Curosurf NNP cord-005646-xhx9pzhj 4433 25 , , , cord-005646-xhx9pzhj 4433 26 Serene Serene NNP cord-005646-xhx9pzhj 4433 27 France France NNP cord-005646-xhx9pzhj 4433 28 ) ) -RRB- cord-005646-xhx9pzhj 4433 29 , , , cord-005646-xhx9pzhj 4433 30 in in IN cord-005646-xhx9pzhj 4433 31 two two CD cord-005646-xhx9pzhj 4433 32 equal equal JJ cord-005646-xhx9pzhj 4433 33 volumes volume NNS cord-005646-xhx9pzhj 4433 34 in in IN cord-005646-xhx9pzhj 4433 35 both both DT cord-005646-xhx9pzhj 4433 36 main main JJ cord-005646-xhx9pzhj 4433 37 bronchus bronchus NN cord-005646-xhx9pzhj 4433 38 , , , cord-005646-xhx9pzhj 4433 39 The the DT cord-005646-xhx9pzhj 4433 40 SpO~ SpO~ NNP cord-005646-xhx9pzhj 4433 41 rose rise VBD cord-005646-xhx9pzhj 4433 42 to to IN cord-005646-xhx9pzhj 4433 43 97 97 CD cord-005646-xhx9pzhj 4433 44 % % NN cord-005646-xhx9pzhj 4433 45 within within IN cord-005646-xhx9pzhj 4433 46 15 15 CD cord-005646-xhx9pzhj 4433 47 rain rain NN cord-005646-xhx9pzhj 4433 48 , , , cord-005646-xhx9pzhj 4433 49 the the DT cord-005646-xhx9pzhj 4433 50 Fie Fie NNP cord-005646-xhx9pzhj 4433 51 2 2 CD cord-005646-xhx9pzhj 4433 52 could could MD cord-005646-xhx9pzhj 4433 53 be be VB cord-005646-xhx9pzhj 4433 54 reduced reduce VBN cord-005646-xhx9pzhj 4433 55 to to IN cord-005646-xhx9pzhj 4433 56 0.6 0.6 CD cord-005646-xhx9pzhj 4433 57 . . . cord-005646-xhx9pzhj 4434 1 Twenty twenty CD cord-005646-xhx9pzhj 4434 2 four four CD cord-005646-xhx9pzhj 4434 3 hours hour NNS cord-005646-xhx9pzhj 4434 4 later later RB cord-005646-xhx9pzhj 4434 5 , , , cord-005646-xhx9pzhj 4434 6 gas gas NN cord-005646-xhx9pzhj 4434 7 exchange exchange NN cord-005646-xhx9pzhj 4434 8 worsened worsen VBD cord-005646-xhx9pzhj 4434 9 again again RB cord-005646-xhx9pzhj 4434 10 ( ( -LRB- cord-005646-xhx9pzhj 4434 11 PaO2 PaO2 NNS cord-005646-xhx9pzhj 4434 12 / / SYM cord-005646-xhx9pzhj 4434 13 FiO2 FiO2 NNS cord-005646-xhx9pzhj 4434 14 ratio ratio NN cord-005646-xhx9pzhj 4434 15 90 90 CD cord-005646-xhx9pzhj 4434 16 ) ) -RRB- cord-005646-xhx9pzhj 4434 17 . . . cord-005646-xhx9pzhj 4435 1 We -PRON- PRP cord-005646-xhx9pzhj 4435 2 increased increase VBD cord-005646-xhx9pzhj 4435 3 the the DT cord-005646-xhx9pzhj 4435 4 PEEP peep NN cord-005646-xhx9pzhj 4435 5 from from IN cord-005646-xhx9pzhj 4435 6 8 8 CD cord-005646-xhx9pzhj 4435 7 to to IN cord-005646-xhx9pzhj 4435 8 11 11 CD cord-005646-xhx9pzhj 4435 9 cmH20 cmH20 NNP cord-005646-xhx9pzhj 4435 10 , , , cord-005646-xhx9pzhj 4435 11 and and CC cord-005646-xhx9pzhj 4435 12 instilled instill VBD cord-005646-xhx9pzhj 4435 13 a a DT cord-005646-xhx9pzhj 4435 14 second second JJ cord-005646-xhx9pzhj 4435 15 dose dose NN cord-005646-xhx9pzhj 4435 16 of of IN cord-005646-xhx9pzhj 4435 17 surfactant surfactant NN cord-005646-xhx9pzhj 4435 18 ( ( -LRB- cord-005646-xhx9pzhj 4435 19 60 60 CD cord-005646-xhx9pzhj 4435 20 mg mg NNP cord-005646-xhx9pzhj 4435 21 / / SYM cord-005646-xhx9pzhj 4435 22 kg kg NNP cord-005646-xhx9pzhj 4435 23 ) ) -RRB- cord-005646-xhx9pzhj 4435 24 . . . cord-005646-xhx9pzhj 4436 1 Again again RB cord-005646-xhx9pzhj 4436 2 , , , cord-005646-xhx9pzhj 4436 3 Fie Fie NNP cord-005646-xhx9pzhj 4436 4 2 2 CD cord-005646-xhx9pzhj 4436 5 could could MD cord-005646-xhx9pzhj 4436 6 be be VB cord-005646-xhx9pzhj 4436 7 reduced reduce VBN cord-005646-xhx9pzhj 4436 8 within within IN cord-005646-xhx9pzhj 4436 9 15 15 CD cord-005646-xhx9pzhj 4436 10 minutes minute NNS cord-005646-xhx9pzhj 4436 11 ( ( -LRB- cord-005646-xhx9pzhj 4436 12 SpO SpO NNP cord-005646-xhx9pzhj 4436 13 2 2 CD cord-005646-xhx9pzhj 4436 14 95 95 CD cord-005646-xhx9pzhj 4436 15 ; ; : cord-005646-xhx9pzhj 4436 16 Fie Fie NNP cord-005646-xhx9pzhj 4436 17 2 2 CD cord-005646-xhx9pzhj 4436 18 0.6 0.6 CD cord-005646-xhx9pzhj 4436 19 . . . cord-005646-xhx9pzhj 4436 20 ) ) -RRB- cord-005646-xhx9pzhj 4436 21 . . . cord-005646-xhx9pzhj 4437 1 The the DT cord-005646-xhx9pzhj 4437 2 patient patient NN cord-005646-xhx9pzhj 4437 3 was be VBD cord-005646-xhx9pzhj 4437 4 weaned wean VBN cord-005646-xhx9pzhj 4437 5 from from IN cord-005646-xhx9pzhj 4437 6 the the DT cord-005646-xhx9pzhj 4437 7 ventilator ventilator NN cord-005646-xhx9pzhj 4437 8 and and CC cord-005646-xhx9pzhj 4437 9 extubated extubate VBN cord-005646-xhx9pzhj 4437 10 on on IN cord-005646-xhx9pzhj 4437 11 the the DT cord-005646-xhx9pzhj 4437 12 tenth tenth JJ cord-005646-xhx9pzhj 4437 13 day day NN cord-005646-xhx9pzhj 4437 14 . . . cord-005646-xhx9pzhj 4438 1 Follow follow VB cord-005646-xhx9pzhj 4438 2 - - HYPH cord-005646-xhx9pzhj 4438 3 up up NN cord-005646-xhx9pzhj 4438 4 at at IN cord-005646-xhx9pzhj 4438 5 four four CD cord-005646-xhx9pzhj 4438 6 month month NN cord-005646-xhx9pzhj 4438 7 showed show VBD cord-005646-xhx9pzhj 4438 8 normal normal JJ cord-005646-xhx9pzhj 4438 9 lung lung NN cord-005646-xhx9pzhj 4438 10 function function NN cord-005646-xhx9pzhj 4438 11 . . . cord-005646-xhx9pzhj 4439 1 We -PRON- PRP cord-005646-xhx9pzhj 4439 2 demonstrate demonstrate VBP cord-005646-xhx9pzhj 4439 3 improvement improvement NN cord-005646-xhx9pzhj 4439 4 in in IN cord-005646-xhx9pzhj 4439 5 oxygenation oxygenation NN cord-005646-xhx9pzhj 4439 6 after after IN cord-005646-xhx9pzhj 4439 7 repeated repeat VBN cord-005646-xhx9pzhj 4439 8 exogenous exogenous JJ cord-005646-xhx9pzhj 4439 9 surfactant surfactant NN cord-005646-xhx9pzhj 4439 10 administrations administration NNS cord-005646-xhx9pzhj 4439 11 . . . cord-005646-xhx9pzhj 4440 1 We -PRON- PRP cord-005646-xhx9pzhj 4440 2 assume assume VBP cord-005646-xhx9pzhj 4440 3 that that IN cord-005646-xhx9pzhj 4440 4 in in IN cord-005646-xhx9pzhj 4440 5 early early JJ cord-005646-xhx9pzhj 4440 6 - - HYPH cord-005646-xhx9pzhj 4440 7 stage stage NN cord-005646-xhx9pzhj 4440 8 ARDS ARDS NNP cord-005646-xhx9pzhj 4440 9 , , , cord-005646-xhx9pzhj 4440 10 surfactant surfactant NN cord-005646-xhx9pzhj 4440 11 may may MD cord-005646-xhx9pzhj 4440 12 potentiate potentiate VB cord-005646-xhx9pzhj 4440 13 shunt shunt NN cord-005646-xhx9pzhj 4440 14 - - HYPH cord-005646-xhx9pzhj 4440 15 reducing reduce VBG cord-005646-xhx9pzhj 4440 16 effect effect NN cord-005646-xhx9pzhj 4440 17 of of IN cord-005646-xhx9pzhj 4440 18 PEEP peep NN cord-005646-xhx9pzhj 4440 19 as as IN cord-005646-xhx9pzhj 4440 20 it -PRON- PRP cord-005646-xhx9pzhj 4440 21 has have VBZ cord-005646-xhx9pzhj 4440 22 been be VBN cord-005646-xhx9pzhj 4440 23 demonstrated demonstrate VBN cord-005646-xhx9pzhj 4440 24 in in IN cord-005646-xhx9pzhj 4440 25 experimental experimental JJ cord-005646-xhx9pzhj 4440 26 model model NN cord-005646-xhx9pzhj 4440 27 of of IN cord-005646-xhx9pzhj 4440 28 ARDS ARDS NNP cord-005646-xhx9pzhj 4440 29 [ [ -LRB- cord-005646-xhx9pzhj 4440 30 4 4 CD cord-005646-xhx9pzhj 4440 31 ] ] -RRB- cord-005646-xhx9pzhj 4440 32 , , , cord-005646-xhx9pzhj 4440 33 and and CC cord-005646-xhx9pzhj 4440 34 allow allow VB cord-005646-xhx9pzhj 4440 35 decrease decrease NN cord-005646-xhx9pzhj 4440 36 in in IN cord-005646-xhx9pzhj 4440 37 Fie2 Fie2 NNP cord-005646-xhx9pzhj 4440 38 . . . cord-005646-xhx9pzhj 4441 1 In in IN cord-005646-xhx9pzhj 4441 2 case case NN cord-005646-xhx9pzhj 4441 3 of of IN cord-005646-xhx9pzhj 4441 4 secondary secondary JJ cord-005646-xhx9pzhj 4441 5 deterioration deterioration NN cord-005646-xhx9pzhj 4441 6 , , , cord-005646-xhx9pzhj 4441 7 we -PRON- PRP cord-005646-xhx9pzhj 4441 8 think think VBP cord-005646-xhx9pzhj 4441 9 that that IN cord-005646-xhx9pzhj 4441 10 a a DT cord-005646-xhx9pzhj 4441 11 second second JJ cord-005646-xhx9pzhj 4441 12 dose dose NN cord-005646-xhx9pzhj 4441 13 of of IN cord-005646-xhx9pzhj 4441 14 surfactant surfactant NN cord-005646-xhx9pzhj 4441 15 should should MD cord-005646-xhx9pzhj 4441 16 be be VB cord-005646-xhx9pzhj 4441 17 administered administer VBN cord-005646-xhx9pzhj 4441 18 . . . cord-005646-xhx9pzhj 4442 1 1 1 LS cord-005646-xhx9pzhj 4442 2 . . . cord-005646-xhx9pzhj 4443 1 Weg Weg NNP cord-005646-xhx9pzhj 4443 2 JG JG NNP cord-005646-xhx9pzhj 4443 3 , , , cord-005646-xhx9pzhj 4443 4 Balk Balk NNP cord-005646-xhx9pzhj 4443 5 RA RA NNP cord-005646-xhx9pzhj 4443 6 , , , cord-005646-xhx9pzhj 4443 7 Tharratt Tharratt NNP cord-005646-xhx9pzhj 4443 8 RS RS NNP cord-005646-xhx9pzhj 4443 9 , , , cord-005646-xhx9pzhj 4443 10 et et NNP cord-005646-xhx9pzhj 4443 11 al al NNP cord-005646-xhx9pzhj 4443 12 . . . cord-005646-xhx9pzhj 4444 1 , , , cord-005646-xhx9pzhj 4444 2 lAMA lama JJ cord-005646-xhx9pzhj 4444 3 1994 1994 CD cord-005646-xhx9pzhj 4444 4 : : : cord-005646-xhx9pzhj 4444 5 272 272 CD cord-005646-xhx9pzhj 4444 6 : : : cord-005646-xhx9pzhj 4444 7 1433 1433 CD cord-005646-xhx9pzhj 4444 8 -8 -8 NNPS cord-005646-xhx9pzhj 4444 9 . . . cord-005646-xhx9pzhj 4444 10 2 2 LS cord-005646-xhx9pzhj 4444 11 . . . cord-005646-xhx9pzhj 4445 1 Spragg Spragg NNP cord-005646-xhx9pzhj 4445 2 RG RG NNP cord-005646-xhx9pzhj 4445 3 , , , cord-005646-xhx9pzhj 4445 4 Gillard Gillard NNP cord-005646-xhx9pzhj 4445 5 N N NNP cord-005646-xhx9pzhj 4445 6 , , , cord-005646-xhx9pzhj 4445 7 Pdchman Pdchman NNP cord-005646-xhx9pzhj 4445 8 P P NNP cord-005646-xhx9pzhj 4445 9 , , , cord-005646-xhx9pzhj 4445 10 et et NNP cord-005646-xhx9pzhj 4445 11 al al NNP cord-005646-xhx9pzhj 4445 12 . . . cord-005646-xhx9pzhj 4446 1 Chest chest NN cord-005646-xhx9pzhj 4447 1 t994 t994 VBN cord-005646-xhx9pzhj 4447 2 : : : cord-005646-xhx9pzhj 4447 3 105 105 CD cord-005646-xhx9pzhj 4447 4 : : SYM cord-005646-xhx9pzhj 4447 5 195 195 CD cord-005646-xhx9pzhj 4447 6 - - SYM cord-005646-xhx9pzhj 4447 7 202 202 CD cord-005646-xhx9pzhj 4447 8 . . . cord-005646-xhx9pzhj 4448 1 3 3 LS cord-005646-xhx9pzhj 4448 2 . . . cord-005646-xhx9pzhj 4449 1 Haslam Haslam NNP cord-005646-xhx9pzhj 4449 2 PL PL NNP cord-005646-xhx9pzhj 4449 3 , , , cord-005646-xhx9pzhj 4449 4 Hughes Hughes NNP cord-005646-xhx9pzhj 4449 5 DA DA NNP cord-005646-xhx9pzhj 4449 6 , , , cord-005646-xhx9pzhj 4449 7 McNaughton McNaughton NNP cord-005646-xhx9pzhj 4449 8 PD PD NNP cord-005646-xhx9pzhj 4449 9 . . . cord-005646-xhx9pzhj 4450 1 et et NNP cord-005646-xhx9pzhj 4450 2 al al NNP cord-005646-xhx9pzhj 4450 3 . . . cord-005646-xhx9pzhj 4451 1 Lancet Lancet NNP cord-005646-xhx9pzhj 4451 2 1994 1994 CD cord-005646-xhx9pzhj 4451 3 343:1009 343:1009 NN cord-005646-xhx9pzhj 4451 4 -11 -11 IN cord-005646-xhx9pzhj 4451 5 . . NN cord-005646-xhx9pzhj 4451 6 4 4 CD cord-005646-xhx9pzhj 4451 7 . . . cord-005646-xhx9pzhj 4452 1 Huang Huang NNP cord-005646-xhx9pzhj 4452 2 YC YC NNP cord-005646-xhx9pzhj 4452 3 , , , cord-005646-xhx9pzhj 4452 4 Caimulti Caimulti NNP cord-005646-xhx9pzhj 4452 5 SP SP NNP cord-005646-xhx9pzhj 4452 6 , , , cord-005646-xhx9pzhj 4452 7 Fawcett Fawcett NNP cord-005646-xhx9pzhj 4452 8 TA TA NNP cord-005646-xhx9pzhj 4452 9 , , , cord-005646-xhx9pzhj 4452 10 et et NNP cord-005646-xhx9pzhj 4452 11 al al NNP cord-005646-xhx9pzhj 4452 12 . . . cord-005646-xhx9pzhj 4453 1 JAppl JAppl NNP cord-005646-xhx9pzhj 4453 2 Physiol Physiol NNP cord-005646-xhx9pzhj 4453 3 1994 1994 CD cord-005646-xhx9pzhj 4453 4 76:991 76:991 CD cord-005646-xhx9pzhj 4453 5 - - HYPH cord-005646-xhx9pzhj 4453 6 1001 1001 CD cord-005646-xhx9pzhj 4453 7 43 43 CD cord-005646-xhx9pzhj 4453 8 % % NN cord-005646-xhx9pzhj 4454 1 ( ( -LRB- cord-005646-xhx9pzhj 4454 2 Ref ref NN cord-005646-xhx9pzhj 4454 3 ) ) -RRB- cord-005646-xhx9pzhj 4454 4 . . . cord-005646-xhx9pzhj 4455 1 The the DT cord-005646-xhx9pzhj 4455 2 aim aim NN cord-005646-xhx9pzhj 4455 3 of of IN cord-005646-xhx9pzhj 4455 4 this this DT cord-005646-xhx9pzhj 4455 5 study study NN cord-005646-xhx9pzhj 4455 6 was be VBD cord-005646-xhx9pzhj 4455 7 to to TO cord-005646-xhx9pzhj 4455 8 verify verify VB cord-005646-xhx9pzhj 4455 9 these these DT cord-005646-xhx9pzhj 4455 10 data datum NNS cord-005646-xhx9pzhj 4455 11 : : : cord-005646-xhx9pzhj 4455 12 Patients/~lethods patients/~lethods RB cord-005646-xhx9pzhj 4455 13 : : : cord-005646-xhx9pzhj 4455 14 All all DT cord-005646-xhx9pzhj 4455 15 pts pt NNS cord-005646-xhx9pzhj 4455 16 admitted admit VBN cord-005646-xhx9pzhj 4455 17 to to IN cord-005646-xhx9pzhj 4455 18 our -PRON- PRP$ cord-005646-xhx9pzhj 4455 19 multidisciplinary multidisciplinary JJ cord-005646-xhx9pzhj 4455 20 NICU NICU NNP cord-005646-xhx9pzhj 4455 21 / / SYM cord-005646-xhx9pzhj 4455 22 PICU PICU NNP cord-005646-xhx9pzhj 4455 23 in in IN cord-005646-xhx9pzhj 4455 24 1995 1995 CD cord-005646-xhx9pzhj 4455 25 were be VBD cord-005646-xhx9pzhj 4455 26 included include VBN cord-005646-xhx9pzhj 4455 27 if if IN cord-005646-xhx9pzhj 4455 28 they -PRON- PRP cord-005646-xhx9pzhj 4455 29 were be VBD cord-005646-xhx9pzhj 4455 30 in in IN cord-005646-xhx9pzhj 4455 31 respiratory respiratory JJ cord-005646-xhx9pzhj 4455 32 failure failure NN cord-005646-xhx9pzhj 4455 33 recruiting recruit VBG cord-005646-xhx9pzhj 4455 34 conventional conventional JJ cord-005646-xhx9pzhj 4455 35 mechanical mechanical JJ cord-005646-xhx9pzhj 4455 36 ventilation ventilation NN cord-005646-xhx9pzhj 4455 37 ( ( -LRB- cord-005646-xhx9pzhj 4455 38 CMV CMV NNP cord-005646-xhx9pzhj 4455 39 ) ) -RRB- cord-005646-xhx9pzhj 4455 40 with with IN cord-005646-xhx9pzhj 4455 41 PEEP peep NN cord-005646-xhx9pzhj 4456 1 > > XX cord-005646-xhx9pzhj 4457 1 _ _ NNP cord-005646-xhx9pzhj 4457 2 6 6 CD cord-005646-xhx9pzhj 4457 3 and and CC cord-005646-xhx9pzhj 4457 4 ' ' `` cord-005646-xhx9pzhj 4457 5 FIG2 FIG2 NNS cord-005646-xhx9pzhj 4458 1 -:2 -:2 NNP cord-005646-xhx9pzhj 4459 1 50 50 CD cord-005646-xhx9pzhj 4459 2 % % NN cord-005646-xhx9pzhj 4459 3 or or CC cord-005646-xhx9pzhj 4459 4 high high JJ cord-005646-xhx9pzhj 4459 5 - - HYPH cord-005646-xhx9pzhj 4459 6 frequency frequency NN cord-005646-xhx9pzhj 4459 7 oscillation oscillation NN cord-005646-xhx9pzhj 4459 8 ventilation ventilation NN cord-005646-xhx9pzhj 4459 9 ( ( -LRB- cord-005646-xhx9pzhj 4459 10 HFO HFO NNP cord-005646-xhx9pzhj 4459 11 ) ) -RRB- cord-005646-xhx9pzhj 4459 12 with with IN cord-005646-xhx9pzhj 4459 13 mean mean JJ cord-005646-xhx9pzhj 4459 14 airway airway NNP cord-005646-xhx9pzhj 4459 15 pressure pressure NN cord-005646-xhx9pzhj 4459 16 _ _ NNP cord-005646-xhx9pzhj 4460 1 > > XX cord-005646-xhx9pzhj 4461 1 t8 t8 NNP cord-005646-xhx9pzhj 4461 2 cm cm NNP cord-005646-xhx9pzhj 4461 3 H20 H20 NNP cord-005646-xhx9pzhj 4461 4 for for IN cord-005646-xhx9pzhj 4461 5 12 12 CD cord-005646-xhx9pzhj 4461 6 or or CC cord-005646-xhx9pzhj 4461 7 more more JJR cord-005646-xhx9pzhj 4461 8 houm houm NNP cord-005646-xhx9pzhj 4461 9 . . . cord-005646-xhx9pzhj 4462 1 Diagnosis diagnosis NN cord-005646-xhx9pzhj 4462 2 , , , cord-005646-xhx9pzhj 4462 3 maximal maximal JJ cord-005646-xhx9pzhj 4462 4 ventilatory ventilatory JJ cord-005646-xhx9pzhj 4462 5 parameters parameter NNS cord-005646-xhx9pzhj 4462 6 , , , cord-005646-xhx9pzhj 4462 7 barotrauma barotrauma NN cord-005646-xhx9pzhj 4462 8 , , , cord-005646-xhx9pzhj 4462 9 organ/ organ/ CD cord-005646-xhx9pzhj 4462 10 system system NN cord-005646-xhx9pzhj 4462 11 failures failure NNS cord-005646-xhx9pzhj 4462 12 , , , cord-005646-xhx9pzhj 4462 13 mechanism mechanism NN cord-005646-xhx9pzhj 4462 14 of of IN cord-005646-xhx9pzhj 4462 15 death death NN cord-005646-xhx9pzhj 4462 16 and and CC cord-005646-xhx9pzhj 4462 17 Glasgow Glasgow NNP cord-005646-xhx9pzhj 4462 18 Oulcome Oulcome NNP cord-005646-xhx9pzhj 4462 19 Scale Scale NNP cord-005646-xhx9pzhj 4462 20 ( ( -LRB- cord-005646-xhx9pzhj 4462 21 GOS GOS NNP cord-005646-xhx9pzhj 4462 22 ) ) -RRB- cord-005646-xhx9pzhj 4462 23 1 1 CD cord-005646-xhx9pzhj 4462 24 and and CC cord-005646-xhx9pzhj 4462 25 6 6 CD cord-005646-xhx9pzhj 4462 26 months month NNS cord-005646-xhx9pzhj 4462 27 after after IN cord-005646-xhx9pzhj 4462 28 study study NN cord-005646-xhx9pzhj 4462 29 entry entry NN cord-005646-xhx9pzhj 4462 30 were be VBD cord-005646-xhx9pzhj 4462 31 prospectively prospectively RB cord-005646-xhx9pzhj 4462 32 collected collect VBN cord-005646-xhx9pzhj 4462 33 . . . cord-005646-xhx9pzhj 4463 1 Results result NNS cord-005646-xhx9pzhj 4463 2 : : : cord-005646-xhx9pzhj 4464 1 685 685 CD cord-005646-xhx9pzhj 4464 2 patients patient NNS cord-005646-xhx9pzhj 4464 3 were be VBD cord-005646-xhx9pzhj 4464 4 admitted admit VBN cord-005646-xhx9pzhj 4464 5 to to IN cord-005646-xhx9pzhj 4464 6 the the DT cord-005646-xhx9pzhj 4464 7 unit unit NN cord-005646-xhx9pzhj 4464 8 , , , cord-005646-xhx9pzhj 4464 9 o1 o1 NNP cord-005646-xhx9pzhj 4464 10 whom whom WP cord-005646-xhx9pzhj 4464 11 337 337 CD cord-005646-xhx9pzhj 4464 12 required require VBD cord-005646-xhx9pzhj 4464 13 mechanical mechanical JJ cord-005646-xhx9pzhj 4464 14 ventilation ventilation NN cord-005646-xhx9pzhj 4464 15 for for IN cord-005646-xhx9pzhj 4464 16 a a DT cord-005646-xhx9pzhj 4464 17 mean mean JJ cord-005646-xhx9pzhj 4464 18 duration duration NN cord-005646-xhx9pzhj 4464 19 of of IN cord-005646-xhx9pzhj 4464 20 4.0 4.0 CD cord-005646-xhx9pzhj 4464 21 days day NNS cord-005646-xhx9pzhj 4464 22 . . . cord-005646-xhx9pzhj 4465 1 Overall overall JJ cord-005646-xhx9pzhj 4465 2 mortality mortality NN cord-005646-xhx9pzhj 4465 3 was be VBD cord-005646-xhx9pzhj 4465 4 5 5 CD cord-005646-xhx9pzhj 4465 5 % % NN cord-005646-xhx9pzhj 4465 6 , , , cord-005646-xhx9pzhj 4465 7 22 22 CD cord-005646-xhx9pzhj 4465 8 patients patient NNS cord-005646-xhx9pzhj 4465 9 fulfilled fulfil VBD cord-005646-xhx9pzhj 4465 10 study study NN cord-005646-xhx9pzhj 4465 11 criteria criterion NNS cord-005646-xhx9pzhj 4465 12 . . . cord-005646-xhx9pzhj 4466 1 17 17 CD cord-005646-xhx9pzhj 4466 2 survivors survivor NNS cord-005646-xhx9pzhj 4466 3 had have VBD cord-005646-xhx9pzhj 4466 4 GOS GOS NNP cord-005646-xhx9pzhj 4466 5 5 5 CD cord-005646-xhx9pzhj 4466 6 , , , cord-005646-xhx9pzhj 4466 7 2 2 CD cord-005646-xhx9pzhj 4466 8 pts pt NNS cord-005646-xhx9pzhj 4466 9 with with IN cord-005646-xhx9pzhj 4466 10 preexisting preexisting JJ cord-005646-xhx9pzhj 4466 11 neurological neurological JJ cord-005646-xhx9pzhj 4466 12 impairment impairment NN cord-005646-xhx9pzhj 4466 13 survived survive VBD cord-005646-xhx9pzhj 4466 14 with with IN cord-005646-xhx9pzhj 4466 15 GOS GOS NNP cord-005646-xhx9pzhj 4466 16 3 3 CD cord-005646-xhx9pzhj 4466 17 . . . cord-005646-xhx9pzhj 4467 1 Neonatal neonatal JJ cord-005646-xhx9pzhj 4467 2 diseases disease NNS cord-005646-xhx9pzhj 4467 3 included include VBD cord-005646-xhx9pzhj 4467 4 hyaline hyaline JJ cord-005646-xhx9pzhj 4467 5 membrane membrane NN cord-005646-xhx9pzhj 4467 6 disease disease NN cord-005646-xhx9pzhj 4467 7 ( ( -LRB- cord-005646-xhx9pzhj 4467 8 7 7 CD cord-005646-xhx9pzhj 4467 9 ) ) -RRB- cord-005646-xhx9pzhj 4467 10 , , , cord-005646-xhx9pzhj 4467 11 meconium meconium NN cord-005646-xhx9pzhj 4467 12 aspiration aspiration NN cord-005646-xhx9pzhj 4467 13 syndrome syndrome NN cord-005646-xhx9pzhj 4467 14 ( ( -LRB- cord-005646-xhx9pzhj 4467 15 4 4 CD cord-005646-xhx9pzhj 4467 16 ) ) -RRB- cord-005646-xhx9pzhj 4467 17 and and CC cord-005646-xhx9pzhj 4467 18 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 4467 19 surgery surgery NN cord-005646-xhx9pzhj 4467 20 ( ( -LRB- cord-005646-xhx9pzhj 4467 21 1 1 CD cord-005646-xhx9pzhj 4467 22 ) ) -RRB- cord-005646-xhx9pzhj 4467 23 , , . cord-005646-xhx9pzhj 4468 1 Pediatric pediatric JJ cord-005646-xhx9pzhj 4468 2 diseases disease NNS cord-005646-xhx9pzhj 4468 3 included include VBD cord-005646-xhx9pzhj 4468 4 bacterial bacterial JJ cord-005646-xhx9pzhj 4468 5 ( ( -LRB- cord-005646-xhx9pzhj 4468 6 1 1 CD cord-005646-xhx9pzhj 4468 7 ) ) -RRB- cord-005646-xhx9pzhj 4468 8 and and CC cord-005646-xhx9pzhj 4468 9 viral viral JJ cord-005646-xhx9pzhj 4468 10 ( ( -LRB- cord-005646-xhx9pzhj 4468 11 5 5 CD cord-005646-xhx9pzhj 4468 12 ) ) -RRB- cord-005646-xhx9pzhj 4468 13 pneumonia pneumonia NN cord-005646-xhx9pzhj 4468 14 , , , cord-005646-xhx9pzhj 4468 15 aspiration aspiration NN cord-005646-xhx9pzhj 4468 16 ( ( -LRB- cord-005646-xhx9pzhj 4468 17 1 1 CD cord-005646-xhx9pzhj 4468 18 ) ) -RRB- cord-005646-xhx9pzhj 4468 19 and and CC cord-005646-xhx9pzhj 4468 20 cardiovascular cardiovascular JJ cord-005646-xhx9pzhj 4468 21 surgery surgery NN cord-005646-xhx9pzhj 4468 22 beyond beyond IN cord-005646-xhx9pzhj 4468 23 the the DT cord-005646-xhx9pzhj 4468 24 neonatal neonatal JJ cord-005646-xhx9pzhj 4468 25 period period NN cord-005646-xhx9pzhj 4468 26 ( ( -LRB- cord-005646-xhx9pzhj 4468 27 3 3 CD cord-005646-xhx9pzhj 4468 28 ) ) -RRB- cord-005646-xhx9pzhj 4468 29 . . . cord-005646-xhx9pzhj 4469 1 1990 1990 CD cord-005646-xhx9pzhj 4469 2 -1994 -1994 NN cord-005646-xhx9pzhj 4469 3 ) ) -RRB- cord-005646-xhx9pzhj 4469 4 . . . cord-005646-xhx9pzhj 4470 1 PATIENTS patient NNS cord-005646-xhx9pzhj 4470 2 AND and CC cord-005646-xhx9pzhj 4470 3 METHODS method NNS cord-005646-xhx9pzhj 4470 4 : : : cord-005646-xhx9pzhj 4471 1 Cefotaxim Cefotaxim NNP cord-005646-xhx9pzhj 4471 2 was be VBD cord-005646-xhx9pzhj 4471 3 used use VBN cord-005646-xhx9pzhj 4471 4 as as IN cord-005646-xhx9pzhj 4471 5 a a DT cord-005646-xhx9pzhj 4471 6 prophylactic prophylactic JJ cord-005646-xhx9pzhj 4471 7 agent agent NN cord-005646-xhx9pzhj 4471 8 in in IN cord-005646-xhx9pzhj 4471 9 43 43 CD cord-005646-xhx9pzhj 4471 10 patients patient NNS cord-005646-xhx9pzhj 4471 11 in in IN cord-005646-xhx9pzhj 4471 12 life life NN cord-005646-xhx9pzhj 4471 13 threatening threaten VBG cord-005646-xhx9pzhj 4471 14 situations situation NNS cord-005646-xhx9pzhj 4471 15 ( ( -LRB- cord-005646-xhx9pzhj 4471 16 e.g. e.g. RB cord-005646-xhx9pzhj 4471 17 multitrauma multitrauma NNP cord-005646-xhx9pzhj 4471 18 , , , cord-005646-xhx9pzhj 4471 19 neurosurgery neurosurgery NNP cord-005646-xhx9pzhj 4471 20 atc atc NNP cord-005646-xhx9pzhj 4471 21 . . NNP cord-005646-xhx9pzhj 4471 22 ) ) -RRB- cord-005646-xhx9pzhj 4471 23 . . . cord-005646-xhx9pzhj 4472 1 More More JJR cord-005646-xhx9pzhj 4472 2 than than IN cord-005646-xhx9pzhj 4472 3 85 85 CD cord-005646-xhx9pzhj 4472 4 % % NN cord-005646-xhx9pzhj 4472 5 children child NNS cord-005646-xhx9pzhj 4472 6 required require VBD cord-005646-xhx9pzhj 4472 7 Cefotaxim Cefotaxim NNP cord-005646-xhx9pzhj 4472 8 for for IN cord-005646-xhx9pzhj 4472 9 the the DT cord-005646-xhx9pzhj 4472 10 treatment treatment NN cord-005646-xhx9pzhj 4472 11 of of IN cord-005646-xhx9pzhj 4472 12 severe severe JJ cord-005646-xhx9pzhj 4472 13 infections infection NNS cord-005646-xhx9pzhj 4472 14 ( ( -LRB- cord-005646-xhx9pzhj 4472 15 epiglotitis epiglotitis NN cord-005646-xhx9pzhj 4472 16 , , , cord-005646-xhx9pzhj 4472 17 meningitis meningitis NN cord-005646-xhx9pzhj 4472 18 , , , cord-005646-xhx9pzhj 4472 19 sepsis sepsis NN cord-005646-xhx9pzhj 4472 20 , , , cord-005646-xhx9pzhj 4472 21 pneumonia pneumonia NN cord-005646-xhx9pzhj 4472 22 mainly mainly RB cord-005646-xhx9pzhj 4472 23 in in IN cord-005646-xhx9pzhj 4472 24 immunodeficient immunodeficient JJ cord-005646-xhx9pzhj 4472 25 and and CC cord-005646-xhx9pzhj 4472 26 neutropenic neutropenic JJ cord-005646-xhx9pzhj 4472 27 patients patient NNS cord-005646-xhx9pzhj 4472 28 ) ) -RRB- cord-005646-xhx9pzhj 4472 29 in in IN cord-005646-xhx9pzhj 4472 30 monotherapy monotherapy NN cord-005646-xhx9pzhj 4472 31 or or CC cord-005646-xhx9pzhj 4472 32 in in IN cord-005646-xhx9pzhj 4472 33 the the DT cord-005646-xhx9pzhj 4472 34 combination combination NN cord-005646-xhx9pzhj 4472 35 with with IN cord-005646-xhx9pzhj 4472 36 the the DT cord-005646-xhx9pzhj 4472 37 other other JJ cord-005646-xhx9pzhj 4472 38 antimicrobial antimicrobial JJ cord-005646-xhx9pzhj 4472 39 agents agent NNS cord-005646-xhx9pzhj 4472 40 . . . cord-005646-xhx9pzhj 4473 1 RESULTS result NNS cord-005646-xhx9pzhj 4473 2 : : : cord-005646-xhx9pzhj 4474 1 Cefotaxim Cefotaxim NNP cord-005646-xhx9pzhj 4474 2 as as IN cord-005646-xhx9pzhj 4474 3 a a DT cord-005646-xhx9pzhj 4474 4 prophylactic prophylactic JJ cord-005646-xhx9pzhj 4474 5 drug drug NN cord-005646-xhx9pzhj 4474 6 was be VBD cord-005646-xhx9pzhj 4474 7 successful successful JJ cord-005646-xhx9pzhj 4474 8 in in IN cord-005646-xhx9pzhj 4474 9 all all DT cord-005646-xhx9pzhj 4474 10 43 43 CD cord-005646-xhx9pzhj 4474 11 cases case NNS cord-005646-xhx9pzhj 4474 12 ( ( -LRB- cord-005646-xhx9pzhj 4474 13 100 100 CD cord-005646-xhx9pzhj 4474 14 % % NN cord-005646-xhx9pzhj 4474 15 ) ) -RRB- cord-005646-xhx9pzhj 4474 16 . . . cord-005646-xhx9pzhj 4475 1 The the DT cord-005646-xhx9pzhj 4475 2 effectivity effectivity NN cord-005646-xhx9pzhj 4475 3 of of IN cord-005646-xhx9pzhj 4475 4 treatment treatment NN cord-005646-xhx9pzhj 4475 5 of of IN cord-005646-xhx9pzhj 4475 6 infections infection NNS cord-005646-xhx9pzhj 4475 7 was be VBD cord-005646-xhx9pzhj 4475 8 82.8 82.8 CD cord-005646-xhx9pzhj 4475 9 % % NN cord-005646-xhx9pzhj 4475 10 ( ( -LRB- cord-005646-xhx9pzhj 4475 11 313 313 CD cord-005646-xhx9pzhj 4475 12 patients patient NNS cord-005646-xhx9pzhj 4475 13 ) ) -RRB- cord-005646-xhx9pzhj 4475 14 . . . cord-005646-xhx9pzhj 4476 1 The the DT cord-005646-xhx9pzhj 4476 2 change change NN cord-005646-xhx9pzhj 4476 3 of of IN cord-005646-xhx9pzhj 4476 4 antibiotic antibiotic JJ cord-005646-xhx9pzhj 4476 5 therapy therapy NN cord-005646-xhx9pzhj 4476 6 required require VBN cord-005646-xhx9pzhj 4476 7 9 9 CD cord-005646-xhx9pzhj 4476 8 patients patient NNS cord-005646-xhx9pzhj 4476 9 ( ( -LRB- cord-005646-xhx9pzhj 4476 10 2.4 2.4 CD cord-005646-xhx9pzhj 4476 11 % % NN cord-005646-xhx9pzhj 4476 12 ) ) -RRB- cord-005646-xhx9pzhj 4476 13 . . . cord-005646-xhx9pzhj 4477 1 40 40 CD cord-005646-xhx9pzhj 4477 2 patients patient NNS cord-005646-xhx9pzhj 4477 3 ( ( -LRB- cord-005646-xhx9pzhj 4477 4 10.6 10.6 CD cord-005646-xhx9pzhj 4477 5 % % NN cord-005646-xhx9pzhj 4477 6 ) ) -RRB- cord-005646-xhx9pzhj 4477 7 died die VBD cord-005646-xhx9pzhj 4477 8 , , , cord-005646-xhx9pzhj 4477 9 but but CC cord-005646-xhx9pzhj 4477 10 only only RB cord-005646-xhx9pzhj 4477 11 in in IN cord-005646-xhx9pzhj 4477 12 12 12 CD cord-005646-xhx9pzhj 4477 13 of of IN cord-005646-xhx9pzhj 4477 14 them -PRON- PRP cord-005646-xhx9pzhj 4477 15 ( ( -LRB- cord-005646-xhx9pzhj 4477 16 3.2 3.2 CD cord-005646-xhx9pzhj 4477 17 % % NN cord-005646-xhx9pzhj 4477 18 ) ) -RRB- cord-005646-xhx9pzhj 4477 19 the the DT cord-005646-xhx9pzhj 4477 20 obduction obduction NN cord-005646-xhx9pzhj 4477 21 confirmed confirm VBD cord-005646-xhx9pzhj 4477 22 infection infection NN cord-005646-xhx9pzhj 4477 23 . . . cord-005646-xhx9pzhj 4478 1 CONCLUSION conclusion NN cord-005646-xhx9pzhj 4478 2 : : : cord-005646-xhx9pzhj 4479 1 We -PRON- PRP cord-005646-xhx9pzhj 4479 2 conclude conclude VBP cord-005646-xhx9pzhj 4479 3 that that IN cord-005646-xhx9pzhj 4479 4 Cefotaxim Cefotaxim NNP cord-005646-xhx9pzhj 4479 5 is be VBZ cord-005646-xhx9pzhj 4479 6 very very RB cord-005646-xhx9pzhj 4479 7 effective effective JJ cord-005646-xhx9pzhj 4479 8 and and CC cord-005646-xhx9pzhj 4479 9 safe safe JJ cord-005646-xhx9pzhj 4479 10 antibiotic antibiotic NN cord-005646-xhx9pzhj 4479 11 and and CC cord-005646-xhx9pzhj 4479 12 represents represent VBZ cord-005646-xhx9pzhj 4479 13 " " `` cord-005646-xhx9pzhj 4479 14 golden golden JJ cord-005646-xhx9pzhj 4479 15 standard standard NN cord-005646-xhx9pzhj 4479 16 " " '' cord-005646-xhx9pzhj 4479 17 in in IN cord-005646-xhx9pzhj 4479 18 the the DT cord-005646-xhx9pzhj 4479 19 treatment treatment NN cord-005646-xhx9pzhj 4479 20 of of IN cord-005646-xhx9pzhj 4479 21 severe severe JJ cord-005646-xhx9pzhj 4479 22 infections infection NNS cord-005646-xhx9pzhj 4479 23 in in IN cord-005646-xhx9pzhj 4479 24 childhood childhood NN cord-005646-xhx9pzhj 4479 25 . . . cord-005646-xhx9pzhj 4480 1 In in IN cord-005646-xhx9pzhj 4480 2 order order NN cord-005646-xhx9pzhj 4480 3 to to TO cord-005646-xhx9pzhj 4480 4 improve improve VB cord-005646-xhx9pzhj 4480 5 nursing nursing NN cord-005646-xhx9pzhj 4480 6 quality quality NN cord-005646-xhx9pzhj 4480 7 , , , cord-005646-xhx9pzhj 4480 8 we -PRON- PRP cord-005646-xhx9pzhj 4480 9 recently recently RB cord-005646-xhx9pzhj 4480 10 adapted adapt VBD cord-005646-xhx9pzhj 4480 11 nursing nursing NN cord-005646-xhx9pzhj 4480 12 care care NN cord-005646-xhx9pzhj 4480 13 to to IN cord-005646-xhx9pzhj 4480 14 the the DT cord-005646-xhx9pzhj 4480 15 " " `` cord-005646-xhx9pzhj 4480 16 five five CD cord-005646-xhx9pzhj 4480 17 nursing nursing NN cord-005646-xhx9pzhj 4480 18 functions function NNS cord-005646-xhx9pzhj 4480 19 " " '' cord-005646-xhx9pzhj 4480 20 ( ( -LRB- cord-005646-xhx9pzhj 4480 21 activities activity NNS cord-005646-xhx9pzhj 4480 22 of of IN cord-005646-xhx9pzhj 4480 23 daily daily JJ cord-005646-xhx9pzhj 4480 24 living living NN cord-005646-xhx9pzhj 4480 25 , , , cord-005646-xhx9pzhj 4480 26 accompagnment accompagnment NN cord-005646-xhx9pzhj 4480 27 in in IN cord-005646-xhx9pzhj 4480 28 crisis crisis NN cord-005646-xhx9pzhj 4480 29 , , , cord-005646-xhx9pzhj 4480 30 treatment treatment NN cord-005646-xhx9pzhj 4480 31 , , , cord-005646-xhx9pzhj 4480 32 prevention prevention NN cord-005646-xhx9pzhj 4480 33 and and CC cord-005646-xhx9pzhj 4480 34 research research NN cord-005646-xhx9pzhj 4480 35 ) ) -RRB- cord-005646-xhx9pzhj 4480 36 as as IN cord-005646-xhx9pzhj 4480 37 described describe VBN cord-005646-xhx9pzhj 4480 38 by by IN cord-005646-xhx9pzhj 4480 39 the the DT cord-005646-xhx9pzhj 4480 40 Swiss Swiss NNP cord-005646-xhx9pzhj 4480 41 Red Red NNP cord-005646-xhx9pzhj 4480 42 Cross Cross NNP cord-005646-xhx9pzhj 4480 43 in in IN cord-005646-xhx9pzhj 4480 44 accordance accordance NN cord-005646-xhx9pzhj 4480 45 to to IN cord-005646-xhx9pzhj 4480 46 the the DT cord-005646-xhx9pzhj 4480 47 new new JJ cord-005646-xhx9pzhj 4480 48 educational educational JJ cord-005646-xhx9pzhj 4480 49 guidelines guideline NNS cord-005646-xhx9pzhj 4480 50 of of IN cord-005646-xhx9pzhj 4480 51 the the DT cord-005646-xhx9pzhj 4480 52 European European NNP cord-005646-xhx9pzhj 4480 53 Community Community NNP cord-005646-xhx9pzhj 4480 54 , , , cord-005646-xhx9pzhj 4480 55 The the DT cord-005646-xhx9pzhj 4480 56 aim aim NN cord-005646-xhx9pzhj 4480 57 of of IN cord-005646-xhx9pzhj 4480 58 this this DT cord-005646-xhx9pzhj 4480 59 study study NN cord-005646-xhx9pzhj 4480 60 was be VBD cord-005646-xhx9pzhj 4480 61 to to TO cord-005646-xhx9pzhj 4480 62 document document VB cord-005646-xhx9pzhj 4480 63 complications complication NNS cord-005646-xhx9pzhj 4480 64 of of IN cord-005646-xhx9pzhj 4480 65 " " `` cord-005646-xhx9pzhj 4480 66 treatment treatment NN cord-005646-xhx9pzhj 4480 67 nursing nursing NN cord-005646-xhx9pzhj 4480 68 function function NN cord-005646-xhx9pzhj 4480 69 " " '' cord-005646-xhx9pzhj 4480 70 . . . cord-005646-xhx9pzhj 4481 1 Methods method NNS cord-005646-xhx9pzhj 4481 2 : : : cord-005646-xhx9pzhj 4482 1 All all DT cord-005646-xhx9pzhj 4482 2 treatment treatment NN cord-005646-xhx9pzhj 4482 3 complications complication NNS cord-005646-xhx9pzhj 4482 4 were be VBD cord-005646-xhx9pzhj 4482 5 prospectively prospectively RB cord-005646-xhx9pzhj 4482 6 collected collect VBN cord-005646-xhx9pzhj 4482 7 by by IN cord-005646-xhx9pzhj 4482 8 the the DT cord-005646-xhx9pzhj 4482 9 nursing nursing NN cord-005646-xhx9pzhj 4482 10 and and CC cord-005646-xhx9pzhj 4482 11 medical medical JJ cord-005646-xhx9pzhj 4482 12 staff staff NN cord-005646-xhx9pzhj 4482 13 . . . cord-005646-xhx9pzhj 4483 1 The the DT cord-005646-xhx9pzhj 4483 2 nursing nursing NN cord-005646-xhx9pzhj 4483 3 staff staff NN cord-005646-xhx9pzhj 4483 4 included include VBD cord-005646-xhx9pzhj 4483 5 patient patient JJ cord-005646-xhx9pzhj 4483 6 ( ( -LRB- cord-005646-xhx9pzhj 4483 7 pt pt NN cord-005646-xhx9pzhj 4483 8 ) ) -RRB- cord-005646-xhx9pzhj 4483 9 name name NN cord-005646-xhx9pzhj 4483 10 , , , cord-005646-xhx9pzhj 4483 11 time time NN cord-005646-xhx9pzhj 4483 12 of of IN cord-005646-xhx9pzhj 4483 13 occurence occurence NN cord-005646-xhx9pzhj 4483 14 and and CC cord-005646-xhx9pzhj 4483 15 exact exact JJ cord-005646-xhx9pzhj 4483 16 description description NN cord-005646-xhx9pzhj 4483 17 of of IN cord-005646-xhx9pzhj 4483 18 complication complication NN cord-005646-xhx9pzhj 4483 19 , , , cord-005646-xhx9pzhj 4483 20 proposal proposal NN cord-005646-xhx9pzhj 4483 21 for for IN cord-005646-xhx9pzhj 4483 22 prevention prevention NN cord-005646-xhx9pzhj 4483 23 and and CC cord-005646-xhx9pzhj 4483 24 information information NN cord-005646-xhx9pzhj 4483 25 of of IN cord-005646-xhx9pzhj 4483 26 parents parent NNS cord-005646-xhx9pzhj 4483 27 . . . cord-005646-xhx9pzhj 4484 1 The the DT cord-005646-xhx9pzhj 4484 2 medical medical JJ cord-005646-xhx9pzhj 4484 3 staff staff NN cord-005646-xhx9pzhj 4484 4 reported report VBD cord-005646-xhx9pzhj 4484 5 type type NN cord-005646-xhx9pzhj 4484 6 of of IN cord-005646-xhx9pzhj 4484 7 complication complication NN cord-005646-xhx9pzhj 4484 8 together together RB cord-005646-xhx9pzhj 4484 9 with with IN cord-005646-xhx9pzhj 4484 10 pt pt NN cord-005646-xhx9pzhj 4484 11 information information NN cord-005646-xhx9pzhj 4484 12 , , , cord-005646-xhx9pzhj 4484 13 diagnosis diagnosis NN cord-005646-xhx9pzhj 4484 14 , , , cord-005646-xhx9pzhj 4484 15 medication medication NN cord-005646-xhx9pzhj 4484 16 , , , cord-005646-xhx9pzhj 4484 17 treatment treatment NN cord-005646-xhx9pzhj 4484 18 and and CC cord-005646-xhx9pzhj 4484 19 interventions intervention NNS cord-005646-xhx9pzhj 4484 20 , , , cord-005646-xhx9pzhj 4484 21 outcome outcome NN cord-005646-xhx9pzhj 4484 22 and and CC cord-005646-xhx9pzhj 4484 23 referral referral NN cord-005646-xhx9pzhj 4484 24 , , , cord-005646-xhx9pzhj 4484 25 All all DT cord-005646-xhx9pzhj 4484 26 complications complication NNS cord-005646-xhx9pzhj 4484 27 were be VBD cord-005646-xhx9pzhj 4484 28 discussed discuss VBN cord-005646-xhx9pzhj 4484 29 in in IN cord-005646-xhx9pzhj 4484 30 monthly monthly JJ cord-005646-xhx9pzhj 4484 31 meetings meeting NNS cord-005646-xhx9pzhj 4484 32 including include VBG cord-005646-xhx9pzhj 4484 33 nursing nursing NN cord-005646-xhx9pzhj 4484 34 and and CC cord-005646-xhx9pzhj 4484 35 medical medical JJ cord-005646-xhx9pzhj 4484 36 staff staff NN cord-005646-xhx9pzhj 4484 37 . . . cord-005646-xhx9pzhj 4485 1 Results result NNS cord-005646-xhx9pzhj 4485 2 : : : cord-005646-xhx9pzhj 4486 1 From from IN cord-005646-xhx9pzhj 4486 2 January January NNP cord-005646-xhx9pzhj 4486 3 until until IN cord-005646-xhx9pzhj 4486 4 December December NNP cord-005646-xhx9pzhj 4486 5 1995 1995 CD cord-005646-xhx9pzhj 4486 6 , , , cord-005646-xhx9pzhj 4486 7 685 685 CD cord-005646-xhx9pzhj 4486 8 pts pt NNS cord-005646-xhx9pzhj 4486 9 were be VBD cord-005646-xhx9pzhj 4486 10 admitted admit VBN cord-005646-xhx9pzhj 4486 11 to to IN cord-005646-xhx9pzhj 4486 12 the the DT cord-005646-xhx9pzhj 4486 13 PICU PICU NNP cord-005646-xhx9pzhj 4486 14 / / SYM cord-005646-xhx9pzhj 4486 15 NICU NICU NNP cord-005646-xhx9pzhj 4486 16 for for IN cord-005646-xhx9pzhj 4486 17 3233 3233 CD cord-005646-xhx9pzhj 4486 18 nursing nursing NN cord-005646-xhx9pzhj 4486 19 days day NNS cord-005646-xhx9pzhj 4486 20 ( ( -LRB- cord-005646-xhx9pzhj 4486 21 81 81 CD cord-005646-xhx9pzhj 4486 22 % % NN cord-005646-xhx9pzhj 4486 23 of of IN cord-005646-xhx9pzhj 4486 24 total total JJ cord-005646-xhx9pzhj 4486 25 bed bed NN cord-005646-xhx9pzhj 4486 26 occupancy occupancy NN cord-005646-xhx9pzhj 4486 27 ) ) -RRB- cord-005646-xhx9pzhj 4486 28 . . . cord-005646-xhx9pzhj 4487 1 337 337 CD cord-005646-xhx9pzhj 4487 2 pts pts NN cord-005646-xhx9pzhj 4487 3 needed need VBN cord-005646-xhx9pzhj 4487 4 endotracheal endotracheal NN cord-005646-xhx9pzhj 4487 5 intubation intubation NN cord-005646-xhx9pzhj 4487 6 for for IN cord-005646-xhx9pzhj 4487 7 an an DT cord-005646-xhx9pzhj 4487 8 average average NN cord-005646-xhx9pzhj 4487 9 of of IN cord-005646-xhx9pzhj 4487 10 4.0 4.0 CD cord-005646-xhx9pzhj 4487 11 days day NNS cord-005646-xhx9pzhj 4487 12 and and CC cord-005646-xhx9pzhj 4487 13 47 47 CD cord-005646-xhx9pzhj 4487 14 pts pt NNS cord-005646-xhx9pzhj 4487 15 required require VBN cord-005646-xhx9pzhj 4487 16 nasal nasal NN cord-005646-xhx9pzhj 4487 17 CPAP cpap NN cord-005646-xhx9pzhj 4487 18 . . . cord-005646-xhx9pzhj 4488 1 26 26 CD cord-005646-xhx9pzhj 4488 2 complications complication NNS cord-005646-xhx9pzhj 4488 3 in in IN cord-005646-xhx9pzhj 4488 4 21 21 CD cord-005646-xhx9pzhj 4488 5 pts pt NNS cord-005646-xhx9pzhj 4488 6 were be VBD cord-005646-xhx9pzhj 4488 7 noted note VBN cord-005646-xhx9pzhj 4488 8 ( ( -LRB- cord-005646-xhx9pzhj 4488 9 1 1 CD cord-005646-xhx9pzhj 4488 10 per per IN cord-005646-xhx9pzhj 4488 11 26 26 CD cord-005646-xhx9pzhj 4488 12 pI pi NN cord-005646-xhx9pzhj 4488 13 ) ) -RRB- cord-005646-xhx9pzhj 4488 14 : : : cord-005646-xhx9pzhj 4488 15 inadequate inadequate JJ cord-005646-xhx9pzhj 4488 16 check check NN cord-005646-xhx9pzhj 4488 17 - - HYPH cord-005646-xhx9pzhj 4488 18 up up NN cord-005646-xhx9pzhj 4488 19 of of IN cord-005646-xhx9pzhj 4488 20 equipment equipment NN cord-005646-xhx9pzhj 4488 21 11 11 CD cord-005646-xhx9pzhj 4488 22 ; ; : cord-005646-xhx9pzhj 4488 23 accidental accidental JJ cord-005646-xhx9pzhj 4488 24 extubation extubation NN cord-005646-xhx9pzhj 4488 25 4 4 CD cord-005646-xhx9pzhj 4488 26 ( ( -LRB- cord-005646-xhx9pzhj 4488 27 1 1 CD cord-005646-xhx9pzhj 4488 28 in in IN cord-005646-xhx9pzhj 4488 29 85 85 CD cord-005646-xhx9pzhj 4488 30 intubated intubate VBN cord-005646-xhx9pzhj 4488 31 pts pts NN cord-005646-xhx9pzhj 4488 32 ) ) -RRB- cord-005646-xhx9pzhj 4488 33 ; ; : cord-005646-xhx9pzhj 4488 34 bedsores bedsore NNS cord-005646-xhx9pzhj 4488 35 3 3 CD cord-005646-xhx9pzhj 4488 36 ; ; , cord-005646-xhx9pzhj 4488 37 false false JJ cord-005646-xhx9pzhj 4488 38 drug drug NN cord-005646-xhx9pzhj 4488 39 dosing dose VBG cord-005646-xhx9pzhj 4488 40 2 2 CD cord-005646-xhx9pzhj 4488 41 ; ; : cord-005646-xhx9pzhj 4488 42 wrong wrong JJ cord-005646-xhx9pzhj 4488 43 drug drug NN cord-005646-xhx9pzhj 4488 44 2 2 CD cord-005646-xhx9pzhj 4488 45 ; ; , cord-005646-xhx9pzhj 4488 46 umbilical umbilical JJ cord-005646-xhx9pzhj 4488 47 bleeding bleeding NN cord-005646-xhx9pzhj 4488 48 2 2 CD cord-005646-xhx9pzhj 4488 49 ; ; : cord-005646-xhx9pzhj 4488 50 wrong wrong JJ cord-005646-xhx9pzhj 4488 51 transfusion transfusion NN cord-005646-xhx9pzhj 4488 52 setup setup NN cord-005646-xhx9pzhj 4488 53 1 1 CD cord-005646-xhx9pzhj 4488 54 ; ; : cord-005646-xhx9pzhj 4488 55 nasal nasal JJ cord-005646-xhx9pzhj 4488 56 septal septal JJ cord-005646-xhx9pzhj 4488 57 necrosis necrosis NN cord-005646-xhx9pzhj 4488 58 1 1 CD cord-005646-xhx9pzhj 4488 59 ) ) -RRB- cord-005646-xhx9pzhj 4488 60 . . . cord-005646-xhx9pzhj 4489 1 There there EX cord-005646-xhx9pzhj 4489 2 was be VBD cord-005646-xhx9pzhj 4489 3 no no DT cord-005646-xhx9pzhj 4489 4 mortality mortality NN cord-005646-xhx9pzhj 4489 5 due due IN cord-005646-xhx9pzhj 4489 6 to to IN cord-005646-xhx9pzhj 4489 7 these these DT cord-005646-xhx9pzhj 4489 8 complications complication NNS cord-005646-xhx9pzhj 4489 9 . . . cord-005646-xhx9pzhj 4490 1 Exact exact JJ cord-005646-xhx9pzhj 4490 2 documention documention NN cord-005646-xhx9pzhj 4490 3 of of IN cord-005646-xhx9pzhj 4490 4 treatment treatment NN cord-005646-xhx9pzhj 4490 5 complications complication NNS cord-005646-xhx9pzhj 4490 6 and and CC cord-005646-xhx9pzhj 4490 7 their -PRON- PRP$ cord-005646-xhx9pzhj 4490 8 meticulous meticulous JJ cord-005646-xhx9pzhj 4490 9 discussion discussion NN cord-005646-xhx9pzhj 4490 10 within within IN cord-005646-xhx9pzhj 4490 11 the the DT cord-005646-xhx9pzhj 4490 12 medical medical JJ cord-005646-xhx9pzhj 4490 13 and and CC cord-005646-xhx9pzhj 4490 14 nursing nursing NN cord-005646-xhx9pzhj 4490 15 staff staff NN cord-005646-xhx9pzhj 4490 16 may may MD cord-005646-xhx9pzhj 4490 17 improve improve VB cord-005646-xhx9pzhj 4490 18 " " `` cord-005646-xhx9pzhj 4490 19 treatment treatment NN cord-005646-xhx9pzhj 4490 20 nursing nursing NN cord-005646-xhx9pzhj 4490 21 function function NN cord-005646-xhx9pzhj 4490 22 " " '' cord-005646-xhx9pzhj 4490 23 . . . cord-005646-xhx9pzhj 4491 1 However however RB cord-005646-xhx9pzhj 4491 2 , , , cord-005646-xhx9pzhj 4491 3 documentation documentation NN cord-005646-xhx9pzhj 4491 4 and and CC cord-005646-xhx9pzhj 4491 5 evaluation evaluation NN cord-005646-xhx9pzhj 4491 6 of of IN cord-005646-xhx9pzhj 4491 7 nursing nursing NN cord-005646-xhx9pzhj 4491 8 within within IN cord-005646-xhx9pzhj 4491 9 all all DT cord-005646-xhx9pzhj 4491 10 " " `` cord-005646-xhx9pzhj 4491 11 five five CD cord-005646-xhx9pzhj 4491 12 nursing nursing NN cord-005646-xhx9pzhj 4491 13 functions function NNS cord-005646-xhx9pzhj 4491 14 " " '' cord-005646-xhx9pzhj 4491 15 will will MD cord-005646-xhx9pzhj 4491 16 be be VB cord-005646-xhx9pzhj 4491 17 nessecary nessecary JJ cord-005646-xhx9pzhj 4491 18 in in IN cord-005646-xhx9pzhj 4491 19 order order NN cord-005646-xhx9pzhj 4491 20 to to TO cord-005646-xhx9pzhj 4491 21 achieve achieve VB cord-005646-xhx9pzhj 4491 22 optimal optimal JJ cord-005646-xhx9pzhj 4491 23 nursing nursing NN cord-005646-xhx9pzhj 4491 24 care care NN cord-005646-xhx9pzhj 4491 25 . . . cord-005646-xhx9pzhj 4492 1 Cardiac cardiac JJ cord-005646-xhx9pzhj 4492 2 output output NN cord-005646-xhx9pzhj 4492 3 determination determination NN cord-005646-xhx9pzhj 4492 4 by by IN cord-005646-xhx9pzhj 4492 5 thermodilution thermodilution NN cord-005646-xhx9pzhj 4492 6 , , , cord-005646-xhx9pzhj 4492 7 using use VBG cord-005646-xhx9pzhj 4492 8 iced ice VBN cord-005646-xhx9pzhj 4492 9 injectate injectate NNP cord-005646-xhx9pzhj 4492 10 has have VBZ cord-005646-xhx9pzhj 4492 11 been be VBN cord-005646-xhx9pzhj 4492 12 shown show VBN cord-005646-xhx9pzhj 4492 13 to to TO cord-005646-xhx9pzhj 4492 14 be be VB cord-005646-xhx9pzhj 4492 15 valid valid JJ cord-005646-xhx9pzhj 4492 16 and and CC cord-005646-xhx9pzhj 4492 17 reliable reliable JJ cord-005646-xhx9pzhj 4492 18 in in IN cord-005646-xhx9pzhj 4492 19 pediatric pediatric JJ cord-005646-xhx9pzhj 4492 20 patients patient NNS cord-005646-xhx9pzhj 4492 21 . . . cord-005646-xhx9pzhj 4493 1 It -PRON- PRP cord-005646-xhx9pzhj 4493 2 has have VBZ cord-005646-xhx9pzhj 4493 3 been be VBN cord-005646-xhx9pzhj 4493 4 demonstrated demonstrate VBN cord-005646-xhx9pzhj 4493 5 in in IN cord-005646-xhx9pzhj 4493 6 adult adult NN cord-005646-xhx9pzhj 4493 7 patients patient NNS cord-005646-xhx9pzhj 4493 8 that that IN cord-005646-xhx9pzhj 4493 9 there there EX cord-005646-xhx9pzhj 4493 10 is be VBZ cord-005646-xhx9pzhj 4493 11 no no DT cord-005646-xhx9pzhj 4493 12 difference difference NN cord-005646-xhx9pzhj 4493 13 in in IN cord-005646-xhx9pzhj 4493 14 cardiac cardiac JJ cord-005646-xhx9pzhj 4493 15 output output NN cord-005646-xhx9pzhj 4493 16 values value NNS cord-005646-xhx9pzhj 4493 17 when when WRB cord-005646-xhx9pzhj 4493 18 using use VBG cord-005646-xhx9pzhj 4493 19 room room NN cord-005646-xhx9pzhj 4493 20 temperature temperature NN cord-005646-xhx9pzhj 4493 21 injectate injectate NN cord-005646-xhx9pzhj 4493 22 as as IN cord-005646-xhx9pzhj 4493 23 compared compare VBN cord-005646-xhx9pzhj 4493 24 to to IN cord-005646-xhx9pzhj 4493 25 iced iced JJ cord-005646-xhx9pzhj 4493 26 temperature temperature NN cord-005646-xhx9pzhj 4493 27 injectate injectate NN cord-005646-xhx9pzhj 4493 28 . . . cord-005646-xhx9pzhj 4494 1 The the DT cord-005646-xhx9pzhj 4494 2 purpose purpose NN cord-005646-xhx9pzhj 4494 3 of of IN cord-005646-xhx9pzhj 4494 4 this this DT cord-005646-xhx9pzhj 4494 5 study study NN cord-005646-xhx9pzhj 4494 6 is be VBZ cord-005646-xhx9pzhj 4494 7 to to TO cord-005646-xhx9pzhj 4494 8 examine examine VB cord-005646-xhx9pzhj 4494 9 the the DT cord-005646-xhx9pzhj 4494 10 effect effect NN cord-005646-xhx9pzhj 4494 11 of of IN cord-005646-xhx9pzhj 4494 12 injectate injectate JJ cord-005646-xhx9pzhj 4494 13 temperature temperature NN cord-005646-xhx9pzhj 4494 14 on on IN cord-005646-xhx9pzhj 4494 15 cardiac cardiac JJ cord-005646-xhx9pzhj 4494 16 output output NN cord-005646-xhx9pzhj 4494 17 values value NNS cord-005646-xhx9pzhj 4494 18 in in IN cord-005646-xhx9pzhj 4494 19 pediatric pediatric JJ cord-005646-xhx9pzhj 4494 20 patients patient NNS cord-005646-xhx9pzhj 4494 21 . . . cord-005646-xhx9pzhj 4495 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 4495 2 study study NN cord-005646-xhx9pzhj 4495 3 consisted consist VBD cord-005646-xhx9pzhj 4495 4 of of IN cord-005646-xhx9pzhj 4495 5 sixteen sixteen CD cord-005646-xhx9pzhj 4495 6 pediatric pediatric JJ cord-005646-xhx9pzhj 4495 7 patients patient NNS cord-005646-xhx9pzhj 4495 8 who who WP cord-005646-xhx9pzhj 4495 9 had have VBD cord-005646-xhx9pzhj 4495 10 oximetric oximetric JJ cord-005646-xhx9pzhj 4495 11 thermodilution thermodilution NN cord-005646-xhx9pzhj 4495 12 catheters catheter NNS cord-005646-xhx9pzhj 4495 13 in in IN cord-005646-xhx9pzhj 4495 14 place place NN cord-005646-xhx9pzhj 4495 15 after after IN cord-005646-xhx9pzhj 4495 16 cardiac cardiac JJ cord-005646-xhx9pzhj 4495 17 surgery surgery NN cord-005646-xhx9pzhj 4495 18 and and CC cord-005646-xhx9pzhj 4495 19 who who WP cord-005646-xhx9pzhj 4495 20 had have VBD cord-005646-xhx9pzhj 4495 21 cardiac cardiac JJ cord-005646-xhx9pzhj 4495 22 output output NN cord-005646-xhx9pzhj 4495 23 determined determine VBN cord-005646-xhx9pzhj 4495 24 using use VBG cord-005646-xhx9pzhj 4495 25 both both CC cord-005646-xhx9pzhj 4495 26 iced iced JJ cord-005646-xhx9pzhj 4495 27 and and CC cord-005646-xhx9pzhj 4495 28 room room NN cord-005646-xhx9pzhj 4495 29 temperature temperature NN cord-005646-xhx9pzhj 4495 30 injectate injectate NNP cord-005646-xhx9pzhj 4495 31 . . . cord-005646-xhx9pzhj 4496 1 With with IN cord-005646-xhx9pzhj 4496 2 each each DT cord-005646-xhx9pzhj 4496 3 patient patient NN cord-005646-xhx9pzhj 4496 4 , , , cord-005646-xhx9pzhj 4496 5 cardiac cardiac JJ cord-005646-xhx9pzhj 4496 6 output output NN cord-005646-xhx9pzhj 4496 7 was be VBD cord-005646-xhx9pzhj 4496 8 measured measure VBN cord-005646-xhx9pzhj 4496 9 once once RB cord-005646-xhx9pzhj 4496 10 on on IN cord-005646-xhx9pzhj 4496 11 the the DT cord-005646-xhx9pzhj 4496 12 day day NN cord-005646-xhx9pzhj 4496 13 of of IN cord-005646-xhx9pzhj 4496 14 surgery surgery NN cord-005646-xhx9pzhj 4496 15 and and CC cord-005646-xhx9pzhj 4496 16 again again RB cord-005646-xhx9pzhj 4496 17 the the DT cord-005646-xhx9pzhj 4496 18 following following JJ cord-005646-xhx9pzhj 4496 19 day day NN cord-005646-xhx9pzhj 4496 20 . . . cord-005646-xhx9pzhj 4497 1 In in IN cord-005646-xhx9pzhj 4497 2 each each DT cord-005646-xhx9pzhj 4497 3 case case NN cord-005646-xhx9pzhj 4497 4 cardiac cardiac JJ cord-005646-xhx9pzhj 4497 5 output output NN cord-005646-xhx9pzhj 4497 6 was be VBD cord-005646-xhx9pzhj 4497 7 measured measure VBN cord-005646-xhx9pzhj 4497 8 using use VBG cord-005646-xhx9pzhj 4497 9 both both CC cord-005646-xhx9pzhj 4497 10 iced iced JJ cord-005646-xhx9pzhj 4497 11 and and CC cord-005646-xhx9pzhj 4497 12 room room NN cord-005646-xhx9pzhj 4497 13 temperature temperature NN cord-005646-xhx9pzhj 4497 14 injectate injectate NNP cord-005646-xhx9pzhj 4497 15 . . . cord-005646-xhx9pzhj 4498 1 Statistical statistical JJ cord-005646-xhx9pzhj 4498 2 analysis analysis NN cord-005646-xhx9pzhj 4498 3 included include VBD cord-005646-xhx9pzhj 4498 4 a a DT cord-005646-xhx9pzhj 4498 5 two two CD cord-005646-xhx9pzhj 4498 6 - - HYPH cord-005646-xhx9pzhj 4498 7 way way NN cord-005646-xhx9pzhj 4498 8 , , , cord-005646-xhx9pzhj 4498 9 repeated repeat VBD cord-005646-xhx9pzhj 4498 10 measures measure NNS cord-005646-xhx9pzhj 4498 11 analysis analysis NN cord-005646-xhx9pzhj 4498 12 of of IN cord-005646-xhx9pzhj 4498 13 variance variance NN cord-005646-xhx9pzhj 4498 14 for for IN cord-005646-xhx9pzhj 4498 15 each each DT cord-005646-xhx9pzhj 4498 16 individual individual JJ cord-005646-xhx9pzhj 4498 17 injectate injectate NN cord-005646-xhx9pzhj 4498 18 administered administer VBN cord-005646-xhx9pzhj 4498 19 and and CC cord-005646-xhx9pzhj 4498 20 no no DT cord-005646-xhx9pzhj 4498 21 significant significant JJ cord-005646-xhx9pzhj 4498 22 differences difference NNS cord-005646-xhx9pzhj 4498 23 were be VBD cord-005646-xhx9pzhj 4498 24 found find VBN cord-005646-xhx9pzhj 4498 25 in in IN cord-005646-xhx9pzhj 4498 26 cardiac cardiac JJ cord-005646-xhx9pzhj 4498 27 output output NN cord-005646-xhx9pzhj 4498 28 . . . cord-005646-xhx9pzhj 4499 1 No no DT cord-005646-xhx9pzhj 4499 2 statistically statistically RB cord-005646-xhx9pzhj 4499 3 significant significant JJ cord-005646-xhx9pzhj 4499 4 differences difference NNS cord-005646-xhx9pzhj 4499 5 were be VBD cord-005646-xhx9pzhj 4499 6 found find VBN cord-005646-xhx9pzhj 4499 7 between between IN cord-005646-xhx9pzhj 4499 8 groups group NNS cord-005646-xhx9pzhj 4499 9 with with IN cord-005646-xhx9pzhj 4499 10 regard regard NN cord-005646-xhx9pzhj 4499 11 to to IN cord-005646-xhx9pzhj 4499 12 the the DT cord-005646-xhx9pzhj 4499 13 order order NN cord-005646-xhx9pzhj 4499 14 of of IN cord-005646-xhx9pzhj 4499 15 injectate injectate NNP cord-005646-xhx9pzhj 4499 16 administration administration NNP cord-005646-xhx9pzhj 4499 17 or or CC cord-005646-xhx9pzhj 4499 18 volume volume NN cord-005646-xhx9pzhj 4499 19 of of IN cord-005646-xhx9pzhj 4499 20 injectate injectate NNP cord-005646-xhx9pzhj 4499 21 used use VBN cord-005646-xhx9pzhj 4499 22 ( ( -LRB- cord-005646-xhx9pzhj 4499 23 i i PRP cord-005646-xhx9pzhj 4499 24 , , , cord-005646-xhx9pzhj 4499 25 e e NNP cord-005646-xhx9pzhj 4499 26 . . NNP cord-005646-xhx9pzhj 4499 27 , , , cord-005646-xhx9pzhj 4499 28 3 3 CD cord-005646-xhx9pzhj 4499 29 or or CC cord-005646-xhx9pzhj 4499 30 5 5 CD cord-005646-xhx9pzhj 4499 31 cc cc NN cord-005646-xhx9pzhj 4499 32 's 's POS cord-005646-xhx9pzhj 4499 33 ) ) -RRB- cord-005646-xhx9pzhj 4499 34 . . . cord-005646-xhx9pzhj 4500 1 The the DT cord-005646-xhx9pzhj 4500 2 correlation correlation NN cord-005646-xhx9pzhj 4500 3 coefficients coefficient NNS cord-005646-xhx9pzhj 4500 4 between between IN cord-005646-xhx9pzhj 4500 5 groups group NNS cord-005646-xhx9pzhj 4500 6 for for IN cord-005646-xhx9pzhj 4500 7 cardiac cardiac JJ cord-005646-xhx9pzhj 4500 8 output output NN cord-005646-xhx9pzhj 4500 9 measurements measurement NNS cord-005646-xhx9pzhj 4500 10 at at IN cord-005646-xhx9pzhj 4500 11 each each DT cord-005646-xhx9pzhj 4500 12 injectate injectate NNP cord-005646-xhx9pzhj 4500 13 administration administration NN cord-005646-xhx9pzhj 4500 14 time time NN cord-005646-xhx9pzhj 4500 15 , , , cord-005646-xhx9pzhj 4500 16 and and CC cord-005646-xhx9pzhj 4500 17 for for IN cord-005646-xhx9pzhj 4500 18 the the DT cord-005646-xhx9pzhj 4500 19 average average JJ cord-005646-xhx9pzhj 4500 20 measurements measurement NNS cord-005646-xhx9pzhj 4500 21 across across IN cord-005646-xhx9pzhj 4500 22 times time NNS cord-005646-xhx9pzhj 4500 23 , , , cord-005646-xhx9pzhj 4500 24 ranged range VBD cord-005646-xhx9pzhj 4500 25 between between IN cord-005646-xhx9pzhj 4500 26 0.81 0.81 CD cord-005646-xhx9pzhj 4500 27 to to IN cord-005646-xhx9pzhj 4500 28 0.94 0.94 CD cord-005646-xhx9pzhj 4500 29 ( ( -LRB- cord-005646-xhx9pzhj 4500 30 p p NN cord-005646-xhx9pzhj 4500 31 < < XX cord-005646-xhx9pzhj 4500 32 .0005 .0005 NNP cord-005646-xhx9pzhj 4500 33 ) ) -RRB- cord-005646-xhx9pzhj 4500 34 . . . cord-005646-xhx9pzhj 4501 1 Preliminary preliminary JJ cord-005646-xhx9pzhj 4501 2 data datum NNS cord-005646-xhx9pzhj 4501 3 analysis analysis NN cord-005646-xhx9pzhj 4501 4 suggests suggest VBZ cord-005646-xhx9pzhj 4501 5 that that IN cord-005646-xhx9pzhj 4501 6 cardiac cardiac JJ cord-005646-xhx9pzhj 4501 7 output output NN cord-005646-xhx9pzhj 4501 8 measurements measurement NNS cord-005646-xhx9pzhj 4501 9 for for IN cord-005646-xhx9pzhj 4501 10 children child NNS cord-005646-xhx9pzhj 4501 11 are be VBP cord-005646-xhx9pzhj 4501 12 not not RB cord-005646-xhx9pzhj 4501 13 effected effect VBN cord-005646-xhx9pzhj 4501 14 by by IN cord-005646-xhx9pzhj 4501 15 the the DT cord-005646-xhx9pzhj 4501 16 temperature temperature NN cord-005646-xhx9pzhj 4501 17 of of IN cord-005646-xhx9pzhj 4501 18 injectate injectate NNP cord-005646-xhx9pzhj 4501 19 . . . cord-005646-xhx9pzhj 4502 1 A a DT cord-005646-xhx9pzhj 4502 2 lenghty lenghty JJ cord-005646-xhx9pzhj 4502 3 stay stay NN cord-005646-xhx9pzhj 4502 4 at at IN cord-005646-xhx9pzhj 4502 5 a a DT cord-005646-xhx9pzhj 4502 6 Paediatric Paediatric NNP cord-005646-xhx9pzhj 4502 7 Intensive Intensive NNP cord-005646-xhx9pzhj 4502 8 Care Care NNP cord-005646-xhx9pzhj 4502 9 Unit Unit NNP cord-005646-xhx9pzhj 4502 10 will will MD cord-005646-xhx9pzhj 4502 11 always always RB cord-005646-xhx9pzhj 4502 12 have have VB cord-005646-xhx9pzhj 4502 13 sideeffects sideeffect NNS cord-005646-xhx9pzhj 4502 14 on on IN cord-005646-xhx9pzhj 4502 15 a a DT cord-005646-xhx9pzhj 4502 16 child child NN cord-005646-xhx9pzhj 4502 17 's 's POS cord-005646-xhx9pzhj 4502 18 well well RB cord-005646-xhx9pzhj 4502 19 - - HYPH cord-005646-xhx9pzhj 4502 20 being being NN cord-005646-xhx9pzhj 4502 21 and and CC cord-005646-xhx9pzhj 4502 22 will will MD cord-005646-xhx9pzhj 4502 23 put put VB cord-005646-xhx9pzhj 4502 24 a a DT cord-005646-xhx9pzhj 4502 25 high high JJ cord-005646-xhx9pzhj 4502 26 strain strain NN cord-005646-xhx9pzhj 4502 27 on on IN cord-005646-xhx9pzhj 4502 28 the the DT cord-005646-xhx9pzhj 4502 29 parents parent NNS cord-005646-xhx9pzhj 4502 30 . . . cord-005646-xhx9pzhj 4503 1 In in IN cord-005646-xhx9pzhj 4503 2 order order NN cord-005646-xhx9pzhj 4503 3 to to TO cord-005646-xhx9pzhj 4503 4 minimize minimize VB cord-005646-xhx9pzhj 4503 5 the the DT cord-005646-xhx9pzhj 4503 6 side side NN cord-005646-xhx9pzhj 4503 7 - - HYPH cord-005646-xhx9pzhj 4503 8 effects effect NNS cord-005646-xhx9pzhj 4503 9 Longterm Longterm NNP cord-005646-xhx9pzhj 4503 10 Intensive Intensive NNP cord-005646-xhx9pzhj 4503 11 Care Care NNP cord-005646-xhx9pzhj 4503 12 Unit Unit NNP cord-005646-xhx9pzhj 4503 13 opened open VBD cord-005646-xhx9pzhj 4503 14 in in IN cord-005646-xhx9pzhj 4503 15 1990 1990 CD cord-005646-xhx9pzhj 4503 16 at at IN cord-005646-xhx9pzhj 4503 17 the the DT cord-005646-xhx9pzhj 4503 18 Childrens Childrens NNP cord-005646-xhx9pzhj 4503 19 ' ' POS cord-005646-xhx9pzhj 4503 20 Hospital Hospital NNP cord-005646-xhx9pzhj 4503 21 . . . cord-005646-xhx9pzhj 4504 1 Admitted admit VBN cord-005646-xhx9pzhj 4504 2 children child NNS cord-005646-xhx9pzhj 4504 3 are be VBP cord-005646-xhx9pzhj 4504 4 all all DT cord-005646-xhx9pzhj 4504 5 ~ongterm ~ongterm NNP cord-005646-xhx9pzhj 4504 6 - - HYPH cord-005646-xhx9pzhj 4504 7 ill ill JJ cord-005646-xhx9pzhj 4504 8 and and CC cord-005646-xhx9pzhj 4504 9 technically technically RB cord-005646-xhx9pzhj 4504 10 - - HYPH cord-005646-xhx9pzhj 4504 11 dependent dependent JJ cord-005646-xhx9pzhj 4504 12 and and CC cord-005646-xhx9pzhj 4504 13 the the DT cord-005646-xhx9pzhj 4504 14 ventilatory ventilatory JJ cord-005646-xhx9pzhj 4504 15 support support NN cord-005646-xhx9pzhj 4504 16 can can MD cord-005646-xhx9pzhj 4504 17 alter alter VB cord-005646-xhx9pzhj 4504 18 from from IN cord-005646-xhx9pzhj 4504 19 a a DT cord-005646-xhx9pzhj 4504 20 tracheostoma tracheostoma NN cord-005646-xhx9pzhj 4504 21 to to IN cord-005646-xhx9pzhj 4504 22 CPAP CPAP NNP cord-005646-xhx9pzhj 4504 23 or or CC cord-005646-xhx9pzhj 4504 24 Portable Portable NNP cord-005646-xhx9pzhj 4504 25 Volume Volume NNP cord-005646-xhx9pzhj 4504 26 Ventilator Ventilator NNP cord-005646-xhx9pzhj 4504 27 . . . cord-005646-xhx9pzhj 4505 1 Nutritional nutritional JJ cord-005646-xhx9pzhj 4505 2 support support NN cord-005646-xhx9pzhj 4505 3 is be VBZ cord-005646-xhx9pzhj 4505 4 applied apply VBN cord-005646-xhx9pzhj 4505 5 by by IN cord-005646-xhx9pzhj 4505 6 gastrostomies gastrostomy NNS cord-005646-xhx9pzhj 4505 7 . . . cord-005646-xhx9pzhj 4506 1 A a DT cord-005646-xhx9pzhj 4506 2 homelike homelike NN cord-005646-xhx9pzhj 4506 3 atmosphere atmosphere NN cord-005646-xhx9pzhj 4506 4 surrounds surround VBZ cord-005646-xhx9pzhj 4506 5 the the DT cord-005646-xhx9pzhj 4506 6 children child NNS cord-005646-xhx9pzhj 4506 7 , , , cord-005646-xhx9pzhj 4506 8 they -PRON- PRP cord-005646-xhx9pzhj 4506 9 share share VBP cord-005646-xhx9pzhj 4506 10 a a DT cord-005646-xhx9pzhj 4506 11 dormitory dormitory NN cord-005646-xhx9pzhj 4506 12 , , , cord-005646-xhx9pzhj 4506 13 a a DT cord-005646-xhx9pzhj 4506 14 living living NN cord-005646-xhx9pzhj 4506 15 - - HYPH cord-005646-xhx9pzhj 4506 16 room room NN cord-005646-xhx9pzhj 4506 17 and and CC cord-005646-xhx9pzhj 4506 18 a a DT cord-005646-xhx9pzhj 4506 19 dining dining NN cord-005646-xhx9pzhj 4506 20 - - HYPH cord-005646-xhx9pzhj 4506 21 room room NN cord-005646-xhx9pzhj 4507 1 The the DT cord-005646-xhx9pzhj 4507 2 main main JJ cord-005646-xhx9pzhj 4507 3 purpose purpose NN cord-005646-xhx9pzhj 4507 4 is be VBZ cord-005646-xhx9pzhj 4507 5 to to TO cord-005646-xhx9pzhj 4507 6 send send VB cord-005646-xhx9pzhj 4507 7 the the DT cord-005646-xhx9pzhj 4507 8 child child NN cord-005646-xhx9pzhj 4507 9 home home RB cord-005646-xhx9pzhj 4507 10 with with IN cord-005646-xhx9pzhj 4507 11 or or CC cord-005646-xhx9pzhj 4507 12 without without IN cord-005646-xhx9pzhj 4507 13 technical technical JJ cord-005646-xhx9pzhj 4507 14 equipment equipment NN cord-005646-xhx9pzhj 4507 15 . . . cord-005646-xhx9pzhj 4508 1 This this DT cord-005646-xhx9pzhj 4508 2 can can MD cord-005646-xhx9pzhj 4508 3 only only RB cord-005646-xhx9pzhj 4508 4 be be VB cord-005646-xhx9pzhj 4508 5 implemented implement VBN cord-005646-xhx9pzhj 4508 6 by by IN cord-005646-xhx9pzhj 4508 7 giving give VBG cord-005646-xhx9pzhj 4508 8 structured structured JJ cord-005646-xhx9pzhj 4508 9 education education NN cord-005646-xhx9pzhj 4508 10 ( ( -LRB- cord-005646-xhx9pzhj 4508 11 theory theory NN cord-005646-xhx9pzhj 4508 12 and and CC cord-005646-xhx9pzhj 4508 13 practice practice NN cord-005646-xhx9pzhj 4508 14 ) ) -RRB- cord-005646-xhx9pzhj 4508 15 to to IN cord-005646-xhx9pzhj 4508 16 all all DT cord-005646-xhx9pzhj 4508 17 categories category NNS cord-005646-xhx9pzhj 4508 18 involved involve VBN cord-005646-xhx9pzhj 4508 19 . . . cord-005646-xhx9pzhj 4509 1 The the DT cord-005646-xhx9pzhj 4509 2 multi multi JJ cord-005646-xhx9pzhj 4509 3 - - JJ cord-005646-xhx9pzhj 4509 4 disciplinary disciplinary JJ cord-005646-xhx9pzhj 4509 5 team team NN cord-005646-xhx9pzhj 4509 6 consists consist VBZ cord-005646-xhx9pzhj 4509 7 of of IN cord-005646-xhx9pzhj 4509 8 one one CD cord-005646-xhx9pzhj 4509 9 anaesthesiologist anaesthesiologist NN cord-005646-xhx9pzhj 4509 10 , , , cord-005646-xhx9pzhj 4509 11 head head NN cord-005646-xhx9pzhj 4509 12 nurse nurse NN cord-005646-xhx9pzhj 4509 13 , , , cord-005646-xhx9pzhj 4509 14 clinical clinical JJ cord-005646-xhx9pzhj 4509 15 specialist specialist NN cord-005646-xhx9pzhj 4509 16 , , , cord-005646-xhx9pzhj 4509 17 RN RN NNP cord-005646-xhx9pzhj 4509 18 nurses nurse NNS cord-005646-xhx9pzhj 4509 19 , , , cord-005646-xhx9pzhj 4509 20 nurses nurse NNS cord-005646-xhx9pzhj 4509 21 , , , cord-005646-xhx9pzhj 4509 22 one one CD cord-005646-xhx9pzhj 4509 23 habilitation habilitation NN cord-005646-xhx9pzhj 4509 24 doctor doctor NN cord-005646-xhx9pzhj 4509 25 , , , cord-005646-xhx9pzhj 4509 26 one one CD cord-005646-xhx9pzhj 4509 27 social social JJ cord-005646-xhx9pzhj 4509 28 worker worker NN cord-005646-xhx9pzhj 4509 29 and and CC cord-005646-xhx9pzhj 4509 30 therapists therapist NNS cord-005646-xhx9pzhj 4509 31 . . . cord-005646-xhx9pzhj 4510 1 Twenty twenty CD cord-005646-xhx9pzhj 4510 2 - - HYPH cord-005646-xhx9pzhj 4510 3 four four CD cord-005646-xhx9pzhj 4510 4 patients patient NNS cord-005646-xhx9pzhj 4510 5 have have VBP cord-005646-xhx9pzhj 4510 6 been be VBN cord-005646-xhx9pzhj 4510 7 admitted admit VBN cord-005646-xhx9pzhj 4510 8 to to IN cord-005646-xhx9pzhj 4510 9 LICU LICU NNP cord-005646-xhx9pzhj 4510 10 during during IN cord-005646-xhx9pzhj 4510 11 these these DT cord-005646-xhx9pzhj 4510 12 six six CD cord-005646-xhx9pzhj 4510 13 years year NNS cord-005646-xhx9pzhj 4510 14 . . . cord-005646-xhx9pzhj 4511 1 Length length NN cord-005646-xhx9pzhj 4511 2 of of IN cord-005646-xhx9pzhj 4511 3 stay stay NN cord-005646-xhx9pzhj 4511 4 was be VBD cord-005646-xhx9pzhj 4511 5 from from IN cord-005646-xhx9pzhj 4511 6 one one CD cord-005646-xhx9pzhj 4511 7 day day NN cord-005646-xhx9pzhj 4511 8 to to IN cord-005646-xhx9pzhj 4511 9 four four CD cord-005646-xhx9pzhj 4511 10 years year NNS cord-005646-xhx9pzhj 4511 11 . . . cord-005646-xhx9pzhj 4512 1 Four four CD cord-005646-xhx9pzhj 4512 2 are be VBP cord-005646-xhx9pzhj 4512 3 presently presently RB cord-005646-xhx9pzhj 4512 4 staying stay VBG cord-005646-xhx9pzhj 4512 5 at at IN cord-005646-xhx9pzhj 4512 6 the the DT cord-005646-xhx9pzhj 4512 7 trait trait NN cord-005646-xhx9pzhj 4512 8 . . . cord-005646-xhx9pzhj 4513 1 The the DT cord-005646-xhx9pzhj 4513 2 assessment assessment NN cord-005646-xhx9pzhj 4513 3 of of IN cord-005646-xhx9pzhj 4513 4 pain pain NN cord-005646-xhx9pzhj 4513 5 in in IN cord-005646-xhx9pzhj 4513 6 children child NNS cord-005646-xhx9pzhj 4513 7 ( ( -LRB- cord-005646-xhx9pzhj 4513 8 0 0 CD cord-005646-xhx9pzhj 4513 9 - - SYM cord-005646-xhx9pzhj 4513 10 3 3 CD cord-005646-xhx9pzhj 4513 11 yrs yrs NN cord-005646-xhx9pzhj 4513 12 ) ) -RRB- cord-005646-xhx9pzhj 4513 13 is be VBZ cord-005646-xhx9pzhj 4513 14 still still RB cord-005646-xhx9pzhj 4513 15 difficult difficult JJ cord-005646-xhx9pzhj 4513 16 , , , cord-005646-xhx9pzhj 4513 17 because because IN cord-005646-xhx9pzhj 4513 18 children child NNS cord-005646-xhx9pzhj 4513 19 of of IN cord-005646-xhx9pzhj 4513 20 this this DT cord-005646-xhx9pzhj 4513 21 age age NN cord-005646-xhx9pzhj 4513 22 have have VBP cord-005646-xhx9pzhj 4513 23 limited limit VBN cord-005646-xhx9pzhj 4513 24 language language NN cord-005646-xhx9pzhj 4513 25 and and CC cord-005646-xhx9pzhj 4513 26 cognitive cognitive JJ cord-005646-xhx9pzhj 4513 27 skills skill NNS cord-005646-xhx9pzhj 4513 28 . . . cord-005646-xhx9pzhj 4514 1 To to TO cord-005646-xhx9pzhj 4514 2 standardize standardize VB cord-005646-xhx9pzhj 4514 3 the the DT cord-005646-xhx9pzhj 4514 4 assessment assessment NN cord-005646-xhx9pzhj 4514 5 of of IN cord-005646-xhx9pzhj 4514 6 postoperative postoperative JJ cord-005646-xhx9pzhj 4514 7 pain pain NN cord-005646-xhx9pzhj 4514 8 and and CC cord-005646-xhx9pzhj 4514 9 distress distress NN cord-005646-xhx9pzhj 4514 10 in in IN cord-005646-xhx9pzhj 4514 11 the the DT cord-005646-xhx9pzhj 4514 12 intensive intensive JJ cord-005646-xhx9pzhj 4514 13 care care NN cord-005646-xhx9pzhj 4514 14 unit unit NN cord-005646-xhx9pzhj 4514 15 an an DT cord-005646-xhx9pzhj 4514 16 observational observational JJ cord-005646-xhx9pzhj 4514 17 mstrument mstrument NN cord-005646-xhx9pzhj 4514 18 was be VBD cord-005646-xhx9pzhj 4514 19 needed need VBN cord-005646-xhx9pzhj 4514 20 that that WDT cord-005646-xhx9pzhj 4514 21 met meet VBD cord-005646-xhx9pzhj 4514 22 several several JJ cord-005646-xhx9pzhj 4514 23 criteria criterion NNS cord-005646-xhx9pzhj 4514 24 . . . cord-005646-xhx9pzhj 4515 1 It -PRON- PRP cord-005646-xhx9pzhj 4515 2 should should MD cord-005646-xhx9pzhj 4515 3 be be VB cord-005646-xhx9pzhj 4515 4 easy easy JJ cord-005646-xhx9pzhj 4515 5 to to TO cord-005646-xhx9pzhj 4515 6 use use VB cord-005646-xhx9pzhj 4515 7 in in IN cord-005646-xhx9pzhj 4515 8 daily daily JJ cord-005646-xhx9pzhj 4515 9 routine routine JJ cord-005646-xhx9pzhj 4515 10 care care NN cord-005646-xhx9pzhj 4515 11 . . . cord-005646-xhx9pzhj 4516 1 be be VB cord-005646-xhx9pzhj 4516 2 suitable suitable JJ cord-005646-xhx9pzhj 4516 3 for for IN cord-005646-xhx9pzhj 4516 4 the the DT cord-005646-xhx9pzhj 4516 5 i.c i.c NNP cord-005646-xhx9pzhj 4516 6 . . NNP cord-005646-xhx9pzhj 4516 7 situation situation NN cord-005646-xhx9pzhj 4516 8 , , , cord-005646-xhx9pzhj 4516 9 and and CC cord-005646-xhx9pzhj 4516 10 in in IN cord-005646-xhx9pzhj 4516 11 children child NNS cord-005646-xhx9pzhj 4516 12 of of IN cord-005646-xhx9pzhj 4516 13 0 0 CD cord-005646-xhx9pzhj 4516 14 - - SYM cord-005646-xhx9pzhj 4516 15 3 3 CD cord-005646-xhx9pzhj 4516 16 hrs hrs NN cord-005646-xhx9pzhj 4516 17 of of IN cord-005646-xhx9pzhj 4516 18 age age NN cord-005646-xhx9pzhj 4516 19 . . . cord-005646-xhx9pzhj 4517 1 The the DT cord-005646-xhx9pzhj 4517 2 COMFORT comfort NN cord-005646-xhx9pzhj 4517 3 scale scale NN cord-005646-xhx9pzhj 4517 4 , , , cord-005646-xhx9pzhj 4517 5 an an DT cord-005646-xhx9pzhj 4517 6 observational observational JJ cord-005646-xhx9pzhj 4517 7 instrument instrument NN cord-005646-xhx9pzhj 4517 8 designed design VBN cord-005646-xhx9pzhj 4517 9 to to TO cord-005646-xhx9pzhj 4517 10 assess assess VB cord-005646-xhx9pzhj 4517 11 distress distress NN cord-005646-xhx9pzhj 4517 12 in in IN cord-005646-xhx9pzhj 4517 13 infants infant NNS cord-005646-xhx9pzhj 4517 14 in in IN cord-005646-xhx9pzhj 4517 15 i.c i.c NNP cord-005646-xhx9pzhj 4517 16 . . NNP cord-005646-xhx9pzhj 4517 17 units unit NNS cord-005646-xhx9pzhj 4517 18 , , , cord-005646-xhx9pzhj 4517 19 met meet VBD cord-005646-xhx9pzhj 4517 20 these these DT cord-005646-xhx9pzhj 4517 21 criteria criterion NNS cord-005646-xhx9pzhj 4517 22 . . . cord-005646-xhx9pzhj 4518 1 To to TO cord-005646-xhx9pzhj 4518 2 accommodate accommodate VB cord-005646-xhx9pzhj 4518 3 the the DT cord-005646-xhx9pzhj 4518 4 use use NN cord-005646-xhx9pzhj 4518 5 of of IN cord-005646-xhx9pzhj 4518 6 the the DT cord-005646-xhx9pzhj 4518 7 COMFORT comfort NN cord-005646-xhx9pzhj 4518 8 scale scale NN cord-005646-xhx9pzhj 4518 9 in in IN cord-005646-xhx9pzhj 4518 10 the the DT cord-005646-xhx9pzhj 4518 11 i.c i.c NNP cord-005646-xhx9pzhj 4518 12 . . NNP cord-005646-xhx9pzhj 4518 13 units unit NNS cord-005646-xhx9pzhj 4518 14 and and CC cord-005646-xhx9pzhj 4518 15 in in IN cord-005646-xhx9pzhj 4518 16 research research NN cord-005646-xhx9pzhj 4518 17 , , , cord-005646-xhx9pzhj 4518 18 nurses nurse NNS cord-005646-xhx9pzhj 4518 19 should should MD cord-005646-xhx9pzhj 4518 20 be be VB cord-005646-xhx9pzhj 4518 21 trained train VBN cord-005646-xhx9pzhj 4518 22 to to TO cord-005646-xhx9pzhj 4518 23 use use VB cord-005646-xhx9pzhj 4518 24 the the DT cord-005646-xhx9pzhj 4518 25 scale scale NN cord-005646-xhx9pzhj 4518 26 . . . cord-005646-xhx9pzhj 4519 1 An an DT cord-005646-xhx9pzhj 4519 2 additional additional JJ cord-005646-xhx9pzhj 4519 3 requirement requirement NN cord-005646-xhx9pzhj 4519 4 was be VBD cord-005646-xhx9pzhj 4519 5 that that IN cord-005646-xhx9pzhj 4519 6 the the DT cord-005646-xhx9pzhj 4519 7 inter inter JJ cord-005646-xhx9pzhj 4519 8 - - JJ cord-005646-xhx9pzhj 4519 9 rater rater JJ cord-005646-xhx9pzhj 4519 10 reliability reliability NN cord-005646-xhx9pzhj 4519 11 should should MD cord-005646-xhx9pzhj 4519 12 be be VB cord-005646-xhx9pzhj 4519 13 sufficiently sufficiently RB cord-005646-xhx9pzhj 4519 14 high high JJ cord-005646-xhx9pzhj 4519 15 , , , cord-005646-xhx9pzhj 4519 16 ( ( -LRB- cord-005646-xhx9pzhj 4519 17 Cohen Cohen NNP cord-005646-xhx9pzhj 4519 18 's 's POS cord-005646-xhx9pzhj 4519 19 kappa kappa NN cord-005646-xhx9pzhj 4519 20 > > XX cord-005646-xhx9pzhj 4519 21 .60 .60 CD cord-005646-xhx9pzhj 4519 22 ) ) -RRB- cord-005646-xhx9pzhj 4519 23 . . . cord-005646-xhx9pzhj 4520 1 Objectives objective NNS cord-005646-xhx9pzhj 4520 2 : : : cord-005646-xhx9pzhj 4520 3 1 1 LS cord-005646-xhx9pzhj 4520 4 ) ) -RRB- cord-005646-xhx9pzhj 4520 5 To to TO cord-005646-xhx9pzhj 4520 6 introduce introduce VB cord-005646-xhx9pzhj 4520 7 the the DT cord-005646-xhx9pzhj 4520 8 COMFORT comfort NN cord-005646-xhx9pzhj 4520 9 scale scale NN cord-005646-xhx9pzhj 4520 10 in in IN cord-005646-xhx9pzhj 4520 11 the the DT cord-005646-xhx9pzhj 4520 12 I.C.U. i.c.u. NN cord-005646-xhx9pzhj 4520 13 ; ; : cord-005646-xhx9pzhj 4520 14 2 2 CD cord-005646-xhx9pzhj 4520 15 ) ) -RRB- cord-005646-xhx9pzhj 4520 16 to to TO cord-005646-xhx9pzhj 4520 17 examine examine VB cord-005646-xhx9pzhj 4520 18 whether whether IN cord-005646-xhx9pzhj 4520 19 this this DT cord-005646-xhx9pzhj 4520 20 instrument instrument NN cord-005646-xhx9pzhj 4520 21 can can MD cord-005646-xhx9pzhj 4520 22 easily easily RB cord-005646-xhx9pzhj 4520 23 , , , cord-005646-xhx9pzhj 4520 24 be be VB cord-005646-xhx9pzhj 4520 25 incorporated incorporate VBN cord-005646-xhx9pzhj 4520 26 into into IN cord-005646-xhx9pzhj 4520 27 routine routine JJ cord-005646-xhx9pzhj 4520 28 care care NN cord-005646-xhx9pzhj 4520 29 ; ; : cord-005646-xhx9pzhj 4520 30 3 3 CD cord-005646-xhx9pzhj 4520 31 ) ) -RRB- cord-005646-xhx9pzhj 4520 32 to to TO cord-005646-xhx9pzhj 4520 33 investigate investigate VB cord-005646-xhx9pzhj 4520 34 the the DT cord-005646-xhx9pzhj 4520 35 inter inter JJ cord-005646-xhx9pzhj 4520 36 - - JJ cord-005646-xhx9pzhj 4520 37 rater rater JJ cord-005646-xhx9pzhj 4520 38 retiabtlity retiabtlity NN cord-005646-xhx9pzhj 4520 39 . . . cord-005646-xhx9pzhj 4521 1 Methods method NNS cord-005646-xhx9pzhj 4521 2 : : : cord-005646-xhx9pzhj 4521 3 The the DT cord-005646-xhx9pzhj 4521 4 COMFORT comfort NN cord-005646-xhx9pzhj 4521 5 scale scale NN cord-005646-xhx9pzhj 4521 6 is be VBZ cord-005646-xhx9pzhj 4521 7 an an DT cord-005646-xhx9pzhj 4521 8 8-item 8-item CD cord-005646-xhx9pzhj 4521 9 instrument instrument NN cord-005646-xhx9pzhj 4521 10 specifically specifically RB cord-005646-xhx9pzhj 4521 11 designed design VBN cord-005646-xhx9pzhj 4521 12 for for IN cord-005646-xhx9pzhj 4521 13 use use NN cord-005646-xhx9pzhj 4521 14 in in IN cord-005646-xhx9pzhj 4521 15 pediatric pediatric JJ cord-005646-xhx9pzhj 4521 16 i i NN cord-005646-xhx9pzhj 4521 17 , , , cord-005646-xhx9pzhj 4521 18 c c NNP cord-005646-xhx9pzhj 4521 19 , , , cord-005646-xhx9pzhj 4521 20 units unit NNS cord-005646-xhx9pzhj 4521 21 and and CC cord-005646-xhx9pzhj 4521 22 contains contain VBZ cord-005646-xhx9pzhj 4521 23 both both DT cord-005646-xhx9pzhj 4521 24 physiological physiological JJ cord-005646-xhx9pzhj 4521 25 items item NNS cord-005646-xhx9pzhj 4521 26 ( ( -LRB- cord-005646-xhx9pzhj 4521 27 heart heart NN cord-005646-xhx9pzhj 4521 28 rate rate NN cord-005646-xhx9pzhj 4521 29 , , , cord-005646-xhx9pzhj 4521 30 blood blood NN cord-005646-xhx9pzhj 4521 31 pressure pressure NN cord-005646-xhx9pzhj 4521 32 ) ) -RRB- cord-005646-xhx9pzhj 4521 33 and and CC cord-005646-xhx9pzhj 4521 34 behavioral behavioral JJ cord-005646-xhx9pzhj 4521 35 items item NNS cord-005646-xhx9pzhj 4521 36 ( ( -LRB- cord-005646-xhx9pzhj 4521 37 e.g. e.g. RB cord-005646-xhx9pzhj 4521 38 , , , cord-005646-xhx9pzhj 4521 39 alertness alertness NN cord-005646-xhx9pzhj 4521 40 behavior behavior NN cord-005646-xhx9pzhj 4521 41 , , , cord-005646-xhx9pzhj 4521 42 calmness calmness NN cord-005646-xhx9pzhj 4521 43 / / SYM cord-005646-xhx9pzhj 4521 44 agitation agitation NN cord-005646-xhx9pzhj 4521 45 , , , cord-005646-xhx9pzhj 4521 46 body body NN cord-005646-xhx9pzhj 4521 47 movement movement NN cord-005646-xhx9pzhj 4521 48 , , , cord-005646-xhx9pzhj 4521 49 facial facial JJ cord-005646-xhx9pzhj 4521 50 expression expression NN cord-005646-xhx9pzhj 4521 51 respiratory respiratory JJ cord-005646-xhx9pzhj 4521 52 response response NN cord-005646-xhx9pzhj 4521 53 , , , cord-005646-xhx9pzhj 4521 54 muscle muscle NN cord-005646-xhx9pzhj 4521 55 tension tension NN cord-005646-xhx9pzhj 4521 56 ) ) -RRB- cord-005646-xhx9pzhj 4521 57 . . . cord-005646-xhx9pzhj 4522 1 The the DT cord-005646-xhx9pzhj 4522 2 observation observation NN cord-005646-xhx9pzhj 4522 3 period period NN cord-005646-xhx9pzhj 4522 4 is be VBZ cord-005646-xhx9pzhj 4522 5 2 2 CD cord-005646-xhx9pzhj 4522 6 minutes minute NNS cord-005646-xhx9pzhj 4522 7 . . . cord-005646-xhx9pzhj 4523 1 The the DT cord-005646-xhx9pzhj 4523 2 scale scale NN cord-005646-xhx9pzhj 4523 3 is be VBZ cord-005646-xhx9pzhj 4523 4 supplemented supplement VBN cord-005646-xhx9pzhj 4523 5 with with IN cord-005646-xhx9pzhj 4523 6 an an DT cord-005646-xhx9pzhj 4523 7 item item NN cord-005646-xhx9pzhj 4523 8 on on IN cord-005646-xhx9pzhj 4523 9 crying cry VBG cord-005646-xhx9pzhj 4523 10 tbr tbr NNP cord-005646-xhx9pzhj 4523 11 children child NNS cord-005646-xhx9pzhj 4523 12 who who WP cord-005646-xhx9pzhj 4523 13 are be VBP cord-005646-xhx9pzhj 4523 14 not not RB cord-005646-xhx9pzhj 4523 15 mechanically mechanically RB cord-005646-xhx9pzhj 4523 16 ventilated ventilate VBN cord-005646-xhx9pzhj 4523 17 . . . cord-005646-xhx9pzhj 4524 1 Groups group NNS cord-005646-xhx9pzhj 4524 2 of of IN cord-005646-xhx9pzhj 4524 3 8 8 CD cord-005646-xhx9pzhj 4524 4 t.c t.c NNP cord-005646-xhx9pzhj 4524 5 . . . cord-005646-xhx9pzhj 4524 6 nurses nurse NNS cord-005646-xhx9pzhj 4524 7 were be VBD cord-005646-xhx9pzhj 4524 8 trained train VBN cord-005646-xhx9pzhj 4524 9 by by IN cord-005646-xhx9pzhj 4524 10 means mean NNS cord-005646-xhx9pzhj 4524 11 of of IN cord-005646-xhx9pzhj 4524 12 video video NN cord-005646-xhx9pzhj 4524 13 's 's POS cord-005646-xhx9pzhj 4524 14 and and CC cord-005646-xhx9pzhj 4524 15 observations observation NNS cord-005646-xhx9pzhj 4524 16 at at IN cord-005646-xhx9pzhj 4524 17 the the DT cord-005646-xhx9pzhj 4524 18 wards ward NNS cord-005646-xhx9pzhj 4524 19 . . . cord-005646-xhx9pzhj 4525 1 After after IN cord-005646-xhx9pzhj 4525 2 the the DT cord-005646-xhx9pzhj 4525 3 training training NN cord-005646-xhx9pzhj 4525 4 , , , cord-005646-xhx9pzhj 4525 5 each each DT cord-005646-xhx9pzhj 4525 6 nurse nurse NN cord-005646-xhx9pzhj 4525 7 completed complete VBD cord-005646-xhx9pzhj 4525 8 10 10 CD cord-005646-xhx9pzhj 4525 9 scores score NNS cord-005646-xhx9pzhj 4525 10 with with IN cord-005646-xhx9pzhj 4525 11 other other JJ cord-005646-xhx9pzhj 4525 12 nurses nurse NNS cord-005646-xhx9pzhj 4525 13 , , , cord-005646-xhx9pzhj 4525 14 after after IN cord-005646-xhx9pzhj 4525 15 which which WDT cord-005646-xhx9pzhj 4525 16 the the DT cord-005646-xhx9pzhj 4525 17 Cohen Cohen NNP cord-005646-xhx9pzhj 4525 18 's 's POS cord-005646-xhx9pzhj 4525 19 kappa kappa NN cord-005646-xhx9pzhj 4525 20 was be VBD cord-005646-xhx9pzhj 4525 21 computed compute VBN cord-005646-xhx9pzhj 4525 22 . . . cord-005646-xhx9pzhj 4526 1 When when WRB cord-005646-xhx9pzhj 4526 2 the the DT cord-005646-xhx9pzhj 4526 3 kappa kappa NN cord-005646-xhx9pzhj 4526 4 's 's POS cord-005646-xhx9pzhj 4526 5 for for IN cord-005646-xhx9pzhj 4526 6 the the DT cord-005646-xhx9pzhj 4526 7 items item NNS cord-005646-xhx9pzhj 4526 8 met meet VBD cord-005646-xhx9pzhj 4526 9 or or CC cord-005646-xhx9pzhj 4526 10 exceeded exceed VBD cord-005646-xhx9pzhj 4526 11 our -PRON- PRP$ cord-005646-xhx9pzhj 4526 12 .60 .60 CD cord-005646-xhx9pzhj 4526 13 criterium criterium NN cord-005646-xhx9pzhj 4526 14 , , , cord-005646-xhx9pzhj 4526 15 a a DT cord-005646-xhx9pzhj 4526 16 new new JJ cord-005646-xhx9pzhj 4526 17 group group NN cord-005646-xhx9pzhj 4526 18 of of IN cord-005646-xhx9pzhj 4526 19 nurses nurse NNS cord-005646-xhx9pzhj 4526 20 was be VBD cord-005646-xhx9pzhj 4526 21 trained train VBN cord-005646-xhx9pzhj 4526 22 . . . cord-005646-xhx9pzhj 4527 1 Results result NNS cord-005646-xhx9pzhj 4527 2 : : : cord-005646-xhx9pzhj 4528 1 To to IN cord-005646-xhx9pzhj 4528 2 date date NN cord-005646-xhx9pzhj 4528 3 , , , cord-005646-xhx9pzhj 4528 4 30 30 CD cord-005646-xhx9pzhj 4528 5 nurses nurse NNS cord-005646-xhx9pzhj 4528 6 have have VBP cord-005646-xhx9pzhj 4528 7 been be VBN cord-005646-xhx9pzhj 4528 8 trained train VBN cord-005646-xhx9pzhj 4528 9 . . . cord-005646-xhx9pzhj 4529 1 Nurses nurse NNS cord-005646-xhx9pzhj 4529 2 find find VBP cord-005646-xhx9pzhj 4529 3 the the DT cord-005646-xhx9pzhj 4529 4 COMFORT comfort NN cord-005646-xhx9pzhj 4529 5 scale scale NN cord-005646-xhx9pzhj 4529 6 easy easy RB cord-005646-xhx9pzhj 4529 7 " " '' cord-005646-xhx9pzhj 4529 8 to to TO cord-005646-xhx9pzhj 4529 9 administer administer VB cord-005646-xhx9pzhj 4529 10 and and CC cord-005646-xhx9pzhj 4529 11 a a DT cord-005646-xhx9pzhj 4529 12 valuable valuable JJ cord-005646-xhx9pzhj 4529 13 addition addition NN cord-005646-xhx9pzhj 4529 14 to to IN cord-005646-xhx9pzhj 4529 15 routine routine JJ cord-005646-xhx9pzhj 4529 16 care care NN cord-005646-xhx9pzhj 4529 17 in in IN cord-005646-xhx9pzhj 4529 18 the the DT cord-005646-xhx9pzhj 4529 19 i.c i.c NNP cord-005646-xhx9pzhj 4529 20 . . NNP cord-005646-xhx9pzhj 4529 21 unit unit NN cord-005646-xhx9pzhj 4529 22 . . . cord-005646-xhx9pzhj 4530 1 The the DT cord-005646-xhx9pzhj 4530 2 Cohen Cohen NNP cord-005646-xhx9pzhj 4530 3 's 's POS cord-005646-xhx9pzhj 4530 4 kappa kappa NN cord-005646-xhx9pzhj 4530 5 's 's POS cord-005646-xhx9pzhj 4530 6 were be VBD cord-005646-xhx9pzhj 4530 7 higher high JJR cord-005646-xhx9pzhj 4530 8 than than IN cord-005646-xhx9pzhj 4530 9 .60 .60 CD cord-005646-xhx9pzhj 4531 1 for for IN cord-005646-xhx9pzhj 4531 2 all all DT cord-005646-xhx9pzhj 4531 3 items item NNS cord-005646-xhx9pzhj 4531 4 that that WDT cord-005646-xhx9pzhj 4531 5 the the DT cord-005646-xhx9pzhj 4531 6 inter inter JJ cord-005646-xhx9pzhj 4531 7 - - JJ cord-005646-xhx9pzhj 4531 8 rater rater JJ cord-005646-xhx9pzhj 4531 9 reliability reliability NN cord-005646-xhx9pzhj 4531 10 was be VBD cord-005646-xhx9pzhj 4531 11 high high JJ cord-005646-xhx9pzhj 4531 12 . . . cord-005646-xhx9pzhj 4532 1 The the DT cord-005646-xhx9pzhj 4532 2 COMFORT comfort NN cord-005646-xhx9pzhj 4532 3 scale scale NN cord-005646-xhx9pzhj 4532 4 is be VBZ cord-005646-xhx9pzhj 4532 5 feasible feasible JJ cord-005646-xhx9pzhj 4532 6 in in IN cord-005646-xhx9pzhj 4532 7 postoperative postoperative JJ cord-005646-xhx9pzhj 4532 8 care care NN cord-005646-xhx9pzhj 4532 9 in in IN cord-005646-xhx9pzhj 4532 10 the the DT cord-005646-xhx9pzhj 4532 11 i.v i.v NNP cord-005646-xhx9pzhj 4532 12 . . NNP cord-005646-xhx9pzhj 4532 13 and and CC cord-005646-xhx9pzhj 4532 14 is be VBZ cord-005646-xhx9pzhj 4532 15 considered consider VBN cord-005646-xhx9pzhj 4532 16 a a DT cord-005646-xhx9pzhj 4532 17 valuable valuable JJ cord-005646-xhx9pzhj 4532 18 instrument instrument NN cord-005646-xhx9pzhj 4532 19 to to TO cord-005646-xhx9pzhj 4532 20 improve improve VB cord-005646-xhx9pzhj 4532 21 and and CC cord-005646-xhx9pzhj 4532 22 maintain maintain VB cord-005646-xhx9pzhj 4532 23 high high JJ cord-005646-xhx9pzhj 4532 24 postoperative postoperative JJ cord-005646-xhx9pzhj 4532 25 quality quality NN cord-005646-xhx9pzhj 4532 26 of of IN cord-005646-xhx9pzhj 4532 27 care care NN cord-005646-xhx9pzhj 4532 28 in in IN cord-005646-xhx9pzhj 4532 29 the the DT cord-005646-xhx9pzhj 4532 30 i.c i.c NNP cord-005646-xhx9pzhj 4532 31 . . NNP cord-005646-xhx9pzhj 4532 32 unit unit NN cord-005646-xhx9pzhj 4532 33 . . . cord-005646-xhx9pzhj 4533 1 Introduction introduction NN cord-005646-xhx9pzhj 4533 2 : : : cord-005646-xhx9pzhj 4534 1 Children child NNS cord-005646-xhx9pzhj 4534 2 with with IN cord-005646-xhx9pzhj 4534 3 neuro neuro JJ cord-005646-xhx9pzhj 4534 4 - - JJ cord-005646-xhx9pzhj 4534 5 muscular muscular JJ cord-005646-xhx9pzhj 4534 6 disease disease NN cord-005646-xhx9pzhj 4534 7 are be VBP cord-005646-xhx9pzhj 4534 8 believed believe VBN cord-005646-xhx9pzhj 4534 9 to to TO cord-005646-xhx9pzhj 4534 10 have have VB cord-005646-xhx9pzhj 4534 11 a a DT cord-005646-xhx9pzhj 4534 12 higher high JJR cord-005646-xhx9pzhj 4534 13 Resting Resting NNP cord-005646-xhx9pzhj 4534 14 Energy Energy NNP cord-005646-xhx9pzhj 4534 15 Expenditure Expenditure NNP cord-005646-xhx9pzhj 4534 16 ( ( -LRB- cord-005646-xhx9pzhj 4534 17 REE REE NNP cord-005646-xhx9pzhj 4534 18 ) ) -RRB- cord-005646-xhx9pzhj 4534 19 , , , cord-005646-xhx9pzhj 4534 20 because because IN cord-005646-xhx9pzhj 4534 21 of of IN cord-005646-xhx9pzhj 4534 22 their -PRON- PRP$ cord-005646-xhx9pzhj 4534 23 increasedwork increasedwork NN cord-005646-xhx9pzhj 4534 24 of of IN cord-005646-xhx9pzhj 4534 25 breathing breathing NN cord-005646-xhx9pzhj 4534 26 . . . cord-005646-xhx9pzhj 4535 1 The the DT cord-005646-xhx9pzhj 4535 2 influence influence NN cord-005646-xhx9pzhj 4535 3 of of IN cord-005646-xhx9pzhj 4535 4 nocturnal nocturnal JJ cord-005646-xhx9pzhj 4535 5 nasal nasal NN cord-005646-xhx9pzhj 4535 6 mask mask NN cord-005646-xhx9pzhj 4535 7 ventilation ventilation NN cord-005646-xhx9pzhj 4535 8 on on IN cord-005646-xhx9pzhj 4535 9 energy energy NN cord-005646-xhx9pzhj 4535 10 metabolism metabolism NN cord-005646-xhx9pzhj 4535 11 and and CC cord-005646-xhx9pzhj 4535 12 nutritional nutritional JJ cord-005646-xhx9pzhj 4535 13 state state NN cord-005646-xhx9pzhj 4535 14 of of IN cord-005646-xhx9pzhj 4535 15 these these DT cord-005646-xhx9pzhj 4535 16 children child NNS cord-005646-xhx9pzhj 4535 17 has have VBZ cord-005646-xhx9pzhj 4535 18 not not RB cord-005646-xhx9pzhj 4535 19 been be VBN cord-005646-xhx9pzhj 4535 20 studied study VBN cord-005646-xhx9pzhj 4535 21 so so RB cord-005646-xhx9pzhj 4535 22 far far RB cord-005646-xhx9pzhj 4535 23 . . . cord-005646-xhx9pzhj 4536 1 Objective objective NN cord-005646-xhx9pzhj 4536 2 : : : cord-005646-xhx9pzhj 4537 1 l l NNP cord-005646-xhx9pzhj 4537 2 , , , cord-005646-xhx9pzhj 4537 3 ls ls NNP cord-005646-xhx9pzhj 4538 1 the the DT cord-005646-xhx9pzhj 4538 2 REE REE NNP cord-005646-xhx9pzhj 4538 3 inereased?2.1s inereased?2.1s NN cord-005646-xhx9pzhj 4538 4 there there RB cord-005646-xhx9pzhj 4539 1 an an DT cord-005646-xhx9pzhj 4539 2 influence influence NN cord-005646-xhx9pzhj 4539 3 of of IN cord-005646-xhx9pzhj 4539 4 nasal nasal NN cord-005646-xhx9pzhj 4539 5 mask mask NN cord-005646-xhx9pzhj 4539 6 ventilation ventilation NN cord-005646-xhx9pzhj 4539 7 on on IN cord-005646-xhx9pzhj 4539 8 the the DT cord-005646-xhx9pzhj 4539 9 REE?3.What ree?3.what WDT cord-005646-xhx9pzhj 4539 10 is be VBZ cord-005646-xhx9pzhj 4539 11 the the DT cord-005646-xhx9pzhj 4539 12 nutritional nutritional JJ cord-005646-xhx9pzhj 4539 13 state?4.What state?4.What NNP cord-005646-xhx9pzhj 4539 14 is be VBZ cord-005646-xhx9pzhj 4539 15 the the DT cord-005646-xhx9pzhj 4539 16 estimated estimate VBN cord-005646-xhx9pzhj 4539 17 total total JJ cord-005646-xhx9pzhj 4539 18 energy energy NN cord-005646-xhx9pzhj 4539 19 expenditure(ETE expenditure(ete NN cord-005646-xhx9pzhj 4539 20 ) ) -RRB- cord-005646-xhx9pzhj 4539 21 in in IN cord-005646-xhx9pzhj 4539 22 relation relation NN cord-005646-xhx9pzhj 4539 23 to to IN cord-005646-xhx9pzhj 4539 24 the the DT cord-005646-xhx9pzhj 4539 25 caloric caloric JJ cord-005646-xhx9pzhj 4539 26 intake intake NN cord-005646-xhx9pzhj 4539 27 ? ? . cord-005646-xhx9pzhj 4540 1 Methods method NNS cord-005646-xhx9pzhj 4540 2 : : : cord-005646-xhx9pzhj 4541 1 A a DT cord-005646-xhx9pzhj 4541 2 pilot pilot NN cord-005646-xhx9pzhj 4541 3 study study NN cord-005646-xhx9pzhj 4541 4 of of IN cord-005646-xhx9pzhj 4541 5 4 4 CD cord-005646-xhx9pzhj 4541 6 patients(12 patients(12 NNP cord-005646-xhx9pzhj 4541 7 - - HYPH cord-005646-xhx9pzhj 4541 8 16 16 CD cord-005646-xhx9pzhj 4541 9 years year NNS cord-005646-xhx9pzhj 4541 10 ) ) -RRB- cord-005646-xhx9pzhj 4541 11 .The .The . cord-005646-xhx9pzhj 4541 12 following follow VBG cord-005646-xhx9pzhj 4541 13 measurements measurement NNS cord-005646-xhx9pzhj 4541 14 were be VBD cord-005646-xhx9pzhj 4541 15 performed perform VBN cord-005646-xhx9pzhj 4541 16 : : : cord-005646-xhx9pzhj 4542 1 l. l. NNP cord-005646-xhx9pzhj 4543 1 Anthropometry.2.Bioelectric Anthropometry.2.Bioelectric NNP cord-005646-xhx9pzhj 4543 2 impedance-3.REE impedance-3.REE NNP cord-005646-xhx9pzhj 4543 3 was be VBD cord-005646-xhx9pzhj 4543 4 measured measure VBN cord-005646-xhx9pzhj 4543 5 by by IN cord-005646-xhx9pzhj 4543 6 indirect indirect JJ cord-005646-xhx9pzhj 4543 7 calorimetry calorimetry NN cord-005646-xhx9pzhj 4543 8 during during IN cord-005646-xhx9pzhj 4543 9 the the DT cord-005646-xhx9pzhj 4543 10 day day NN cord-005646-xhx9pzhj 4543 11 ( ( -LRB- cord-005646-xhx9pzhj 4543 12 in in IN cord-005646-xhx9pzhj 4543 13 bed bed NN cord-005646-xhx9pzhj 4543 14 ) ) -RRB- cord-005646-xhx9pzhj 4543 15 with with IN cord-005646-xhx9pzhj 4543 16 and and CC cord-005646-xhx9pzhj 4543 17 without without IN cord-005646-xhx9pzhj 4543 18 nasal nasal NN cord-005646-xhx9pzhj 4543 19 mask mask NN cord-005646-xhx9pzhj 4543 20 ventUation ventuation NN cord-005646-xhx9pzhj 4544 1 , , , cord-005646-xhx9pzhj 4544 2 REE REE NNP cord-005646-xhx9pzhj 4544 3 was be VBD cord-005646-xhx9pzhj 4544 4 compared compare VBN cord-005646-xhx9pzhj 4544 5 with with IN cord-005646-xhx9pzhj 4544 6 predicted predict VBN cord-005646-xhx9pzhj 4544 7 REE ree NN cord-005646-xhx9pzhj 4544 8 according accord VBG cord-005646-xhx9pzhj 4544 9 to to IN cord-005646-xhx9pzhj 4544 10 Schofield(PEE),4.Caloric schofield(pee),4.caloric NN cord-005646-xhx9pzhj 4544 11 - - NN cord-005646-xhx9pzhj 4544 12 intake intake NN cord-005646-xhx9pzhj 4544 13 and and CC cord-005646-xhx9pzhj 4544 14 activities activity NNS cord-005646-xhx9pzhj 4544 15 were be VBD cord-005646-xhx9pzhj 4544 16 recorded record VBN cord-005646-xhx9pzhj 4544 17 during during IN cord-005646-xhx9pzhj 4544 18 48 48 CD cord-005646-xhx9pzhj 4544 19 hour hour NN cord-005646-xhx9pzhj 4544 20 before before IN cord-005646-xhx9pzhj 4544 21 measurement.5.Total measurement.5.Total NNP cord-005646-xhx9pzhj 4544 22 energy energy NNP cord-005646-xhx9pzhj 4544 23 expenditure expenditure NN cord-005646-xhx9pzhj 4544 24 was be VBD cord-005646-xhx9pzhj 4544 25 calculated calculate VBN cord-005646-xhx9pzhj 4544 26 as as IN cord-005646-xhx9pzhj 4544 27 follows follow VBZ cord-005646-xhx9pzhj 4544 28 : : : cord-005646-xhx9pzhj 4544 29 measured measure VBN cord-005646-xhx9pzhj 4544 30 REE REE NNP cord-005646-xhx9pzhj 4544 31 x x NN cord-005646-xhx9pzhj 4544 32 estimated estimated JJ cord-005646-xhx9pzhj 4544 33 activity activity NN cord-005646-xhx9pzhj 4544 34 factor factor NN cord-005646-xhx9pzhj 4544 35 . . . cord-005646-xhx9pzhj 4545 1 Results result NNS cord-005646-xhx9pzhj 4545 2 : : : cord-005646-xhx9pzhj 4545 3 tin tin VB cord-005646-xhx9pzhj 4545 4 all all DT cord-005646-xhx9pzhj 4545 5 children child NNS cord-005646-xhx9pzhj 4545 6 weight weight NN cord-005646-xhx9pzhj 4545 7 for for IN cord-005646-xhx9pzhj 4545 8 height height NN cord-005646-xhx9pzhj 4545 9 was be VBD cord-005646-xhx9pzhj 4545 10 too too RB cord-005646-xhx9pzhj 4545 11 low low JJ cord-005646-xhx9pzhj 4545 12 , , , cord-005646-xhx9pzhj 4545 13 < < XX cord-005646-xhx9pzhj 4545 14 p3.2.AII p3.2.AII NNP cord-005646-xhx9pzhj 4546 1 children child NNS cord-005646-xhx9pzhj 4546 2 had have VBD cord-005646-xhx9pzhj 4546 3 a a DT cord-005646-xhx9pzhj 4546 4 low low JJ cord-005646-xhx9pzhj 4546 5 % % NN cord-005646-xhx9pzhj 4546 6 of of IN cord-005646-xhx9pzhj 4546 7 fat.3.According fat.3.according NN cord-005646-xhx9pzhj 4546 8 to to IN cord-005646-xhx9pzhj 4546 9 the the DT cord-005646-xhx9pzhj 4546 10 healthy healthy JJ cord-005646-xhx9pzhj 4546 11 group group NN cord-005646-xhx9pzhj 4546 12 , , , cord-005646-xhx9pzhj 4546 13 REE REE NNP cord-005646-xhx9pzhj 4546 14 is be VBZ cord-005646-xhx9pzhj 4546 15 not not RB cord-005646-xhx9pzhj 4547 1 increased.4,Nasal increased.4,Nasal NNP cord-005646-xhx9pzhj 4547 2 mask mask NN cord-005646-xhx9pzhj 4547 3 ventilation ventilation NN cord-005646-xhx9pzhj 4547 4 lowered lower VBD cord-005646-xhx9pzhj 4547 5 REE ree NN cord-005646-xhx9pzhj 4547 6 in in IN cord-005646-xhx9pzhj 4547 7 2 2 CD cord-005646-xhx9pzhj 4547 8 patients patient NNS cord-005646-xhx9pzhj 4547 9 , , , cord-005646-xhx9pzhj 4547 10 in in IN cord-005646-xhx9pzhj 4547 11 1 1 CD cord-005646-xhx9pzhj 4547 12 patient patient NN cord-005646-xhx9pzhj 4547 13 we -PRON- PRP cord-005646-xhx9pzhj 4547 14 measured measure VBD cord-005646-xhx9pzhj 4547 15 a a DT cord-005646-xhx9pzhj 4547 16 clear clear JJ cord-005646-xhx9pzhj 4547 17 decrease decrease NN cord-005646-xhx9pzhj 4547 18 . . . cord-005646-xhx9pzhj 4548 1 Conclueion conclueion NN cord-005646-xhx9pzhj 4548 2 : : : cord-005646-xhx9pzhj 4549 1 l. l. NNP cord-005646-xhx9pzhj 4550 1 Anthropometry Anthropometry NNP cord-005646-xhx9pzhj 4550 2 and and CC cord-005646-xhx9pzhj 4550 3 indirect indirect JJ cord-005646-xhx9pzhj 4550 4 calorimetry calorimetry NN cord-005646-xhx9pzhj 4550 5 were be VBD cord-005646-xhx9pzhj 4550 6 helpful helpful JJ cord-005646-xhx9pzhj 4550 7 in in IN cord-005646-xhx9pzhj 4550 8 evaluating evaluate VBG cord-005646-xhx9pzhj 4550 9 the the DT cord-005646-xhx9pzhj 4550 10 nutritional nutritional JJ cord-005646-xhx9pzhj 4550 11 state.2.There state.2.there NN cord-005646-xhx9pzhj 4551 1 is be VBZ cord-005646-xhx9pzhj 4551 2 no no DT cord-005646-xhx9pzhj 4551 3 increased increase VBN cord-005646-xhx9pzhj 4551 4 REE ree NN cord-005646-xhx9pzhj 4551 5 , , , cord-005646-xhx9pzhj 4551 6 in in IN cord-005646-xhx9pzhj 4551 7 t t NN cord-005646-xhx9pzhj 4551 8 patient patient NN cord-005646-xhx9pzhj 4551 9 there there EX cord-005646-xhx9pzhj 4551 10 is be VBZ cord-005646-xhx9pzhj 4551 11 clearly clearly RB cord-005646-xhx9pzhj 4551 12 effect effect NN cord-005646-xhx9pzhj 4551 13 of of IN cord-005646-xhx9pzhj 4551 14 nasal nasal NN cord-005646-xhx9pzhj 4551 15 mask mask NN cord-005646-xhx9pzhj 4551 16 ventilation.3.When ventilation.3.when NN cord-005646-xhx9pzhj 4551 17 caloric caloric JJ cord-005646-xhx9pzhj 4551 18 intake intake NN cord-005646-xhx9pzhj 4551 19 was be VBD cord-005646-xhx9pzhj 4551 20 related relate VBN cord-005646-xhx9pzhj 4551 21 to to IN cord-005646-xhx9pzhj 4551 22 REE ree NN cord-005646-xhx9pzhj 4551 23 and and CC cord-005646-xhx9pzhj 4551 24 level level NN cord-005646-xhx9pzhj 4551 25 of of IN cord-005646-xhx9pzhj 4551 26 activity activity NN cord-005646-xhx9pzhj 4551 27 2 2 CD cord-005646-xhx9pzhj 4551 28 patients patient NNS cord-005646-xhx9pzhj 4551 29 had have VBD cord-005646-xhx9pzhj 4551 30 too too RB cord-005646-xhx9pzhj 4551 31 low low JJ cord-005646-xhx9pzhj 4551 32 caloric caloric JJ cord-005646-xhx9pzhj 4551 33 intake.4.The intake.4.The NNP cord-005646-xhx9pzhj 4551 34 influence influence NN cord-005646-xhx9pzhj 4551 35 of of IN cord-005646-xhx9pzhj 4551 36 nocturnal nocturnal JJ cord-005646-xhx9pzhj 4551 37 nasal nasal NN cord-005646-xhx9pzhj 4551 38 mask mask NN cord-005646-xhx9pzhj 4551 39 ventilation ventilation NN cord-005646-xhx9pzhj 4551 40 and and CC cord-005646-xhx9pzhj 4551 41 nutritional nutritional JJ cord-005646-xhx9pzhj 4551 42 assessment assessment NN cord-005646-xhx9pzhj 4551 43 should should MD cord-005646-xhx9pzhj 4551 44 be be VB cord-005646-xhx9pzhj 4551 45 evaluated evaluate VBN cord-005646-xhx9pzhj 4551 46 longitudinally longitudinally RB cord-005646-xhx9pzhj 4551 47 . . . cord-005646-xhx9pzhj 4552 1 Increasing increase VBG cord-005646-xhx9pzhj 4552 2 awareness awareness NN cord-005646-xhx9pzhj 4552 3 that that WDT cord-005646-xhx9pzhj 4552 4 the the DT cord-005646-xhx9pzhj 4552 5 neonate neonate NN cord-005646-xhx9pzhj 4552 6 can can MD cord-005646-xhx9pzhj 4552 7 percept percept VB cord-005646-xhx9pzhj 4552 8 pain pain NN cord-005646-xhx9pzhj 4552 9 and and CC cord-005646-xhx9pzhj 4552 10 suffer suffer VB cord-005646-xhx9pzhj 4552 11 following follow VBG cord-005646-xhx9pzhj 4552 12 surgical surgical JJ cord-005646-xhx9pzhj 4552 13 procedures procedure NNS cord-005646-xhx9pzhj 4552 14 , , , cord-005646-xhx9pzhj 4552 15 has have VBZ cord-005646-xhx9pzhj 4552 16 major major JJ cord-005646-xhx9pzhj 4552 17 impact impact NN cord-005646-xhx9pzhj 4552 18 on on IN cord-005646-xhx9pzhj 4552 19 pain pain NN cord-005646-xhx9pzhj 4552 20 management management NN cord-005646-xhx9pzhj 4552 21 . . . cord-005646-xhx9pzhj 4553 1 In in IN cord-005646-xhx9pzhj 4553 2 our -PRON- PRP$ cord-005646-xhx9pzhj 4553 3 unit unit NN cord-005646-xhx9pzhj 4553 4 continuous continuous JJ cord-005646-xhx9pzhj 4553 5 morphine morphine NN cord-005646-xhx9pzhj 4553 6 infusion infusion NN cord-005646-xhx9pzhj 4553 7 ( ( -LRB- cord-005646-xhx9pzhj 4553 8 t0/~g t0/~g NNP cord-005646-xhx9pzhj 4553 9 / / SYM cord-005646-xhx9pzhj 4553 10 kg kg NN cord-005646-xhx9pzhj 4553 11 / / SYM cord-005646-xhx9pzhj 4553 12 hr hr NN cord-005646-xhx9pzhj 4553 13 ) ) -RRB- cord-005646-xhx9pzhj 4553 14 was be VBD cord-005646-xhx9pzhj 4553 15 introduced introduce VBN cord-005646-xhx9pzhj 4553 16 from from IN cord-005646-xhx9pzhj 4553 17 January January NNP cord-005646-xhx9pzhj 4553 18 1990 1990 CD cord-005646-xhx9pzhj 4553 19 as as IN cord-005646-xhx9pzhj 4553 20 a a DT cord-005646-xhx9pzhj 4553 21 standard standard JJ cord-005646-xhx9pzhj 4553 22 medicatton medicatton NN cord-005646-xhx9pzhj 4553 23 following follow VBG cord-005646-xhx9pzhj 4553 24 surgical surgical JJ cord-005646-xhx9pzhj 4553 25 procedures procedure NNS cord-005646-xhx9pzhj 4553 26 . . . cord-005646-xhx9pzhj 4554 1 Before before IN cord-005646-xhx9pzhj 4554 2 1990 1990 CD cord-005646-xhx9pzhj 4554 3 Morphine morphine NN cord-005646-xhx9pzhj 4554 4 was be VBD cord-005646-xhx9pzhj 4554 5 given give VBN cord-005646-xhx9pzhj 4554 6 as as IN cord-005646-xhx9pzhj 4554 7 a a DT cord-005646-xhx9pzhj 4554 8 bolus bolus NN cord-005646-xhx9pzhj 4554 9 ( ( -LRB- cord-005646-xhx9pzhj 4554 10 i.m i.m NNP cord-005646-xhx9pzhj 4554 11 . . NNP cord-005646-xhx9pzhj 4554 12 , , , cord-005646-xhx9pzhj 4554 13 i.v i.v NNP cord-005646-xhx9pzhj 4554 14 . . NNP cord-005646-xhx9pzhj 4554 15 , , , cord-005646-xhx9pzhj 4554 16 rectal rectal NN cord-005646-xhx9pzhj 4554 17 ) ) -RRB- cord-005646-xhx9pzhj 4554 18 of of IN cord-005646-xhx9pzhj 4554 19 100/~g 100/~g CD cord-005646-xhx9pzhj 4555 1 /kg /kg NFP cord-005646-xhx9pzhj 4555 2 up up RB cord-005646-xhx9pzhj 4555 3 till till IN cord-005646-xhx9pzhj 4555 4 four four CD cord-005646-xhx9pzhj 4555 5 times time NNS cord-005646-xhx9pzhj 4555 6 a a DT cord-005646-xhx9pzhj 4555 7 day day NN cord-005646-xhx9pzhj 4555 8 . . . cord-005646-xhx9pzhj 4556 1 Repeated repeat VBN cord-005646-xhx9pzhj 4556 2 gifts gift NNS cord-005646-xhx9pzhj 4556 3 of of IN cord-005646-xhx9pzhj 4556 4 morphine morphine NN cord-005646-xhx9pzhj 4556 5 were be VBD cord-005646-xhx9pzhj 4556 6 only only RB cord-005646-xhx9pzhj 4556 7 gwen gwen NNP cord-005646-xhx9pzhj 4556 8 following follow VBG cord-005646-xhx9pzhj 4556 9 observation observation NN cord-005646-xhx9pzhj 4556 10 by by IN cord-005646-xhx9pzhj 4556 11 the the DT cord-005646-xhx9pzhj 4556 12 nurse nurse NN cord-005646-xhx9pzhj 4556 13 that that IN cord-005646-xhx9pzhj 4556 14 the the DT cord-005646-xhx9pzhj 4556 15 child child NN cord-005646-xhx9pzhj 4556 16 experienced experience VBD cord-005646-xhx9pzhj 4556 17 pain pain NN cord-005646-xhx9pzhj 4556 18 . . . cord-005646-xhx9pzhj 4557 1 Aim Aim NNP cord-005646-xhx9pzhj 4557 2 of of IN cord-005646-xhx9pzhj 4557 3 the the DT cord-005646-xhx9pzhj 4557 4 study study NN cord-005646-xhx9pzhj 4557 5 : : : cord-005646-xhx9pzhj 4557 6 To to TO cord-005646-xhx9pzhj 4557 7 evaluate evaluate VB cord-005646-xhx9pzhj 4557 8 pain pain NN cord-005646-xhx9pzhj 4557 9 management management NN cord-005646-xhx9pzhj 4557 10 before before IN cord-005646-xhx9pzhj 4557 11 and and CC cord-005646-xhx9pzhj 4557 12 tbllowing tbllowe VBG cord-005646-xhx9pzhj 4557 13 introduction introduction NN cord-005646-xhx9pzhj 4557 14 of of IN cord-005646-xhx9pzhj 4557 15 a a DT cord-005646-xhx9pzhj 4557 16 continuous continuous JJ cord-005646-xhx9pzhj 4557 17 morphine morphine NN cord-005646-xhx9pzhj 4557 18 infusion infusion NN cord-005646-xhx9pzhj 4557 19 for for IN cord-005646-xhx9pzhj 4557 20 postoperative postoperative JJ cord-005646-xhx9pzhj 4557 21 pain pain NN cord-005646-xhx9pzhj 4557 22 in in IN cord-005646-xhx9pzhj 4557 23 our -PRON- PRP$ cord-005646-xhx9pzhj 4557 24 ICU ICU NNP cord-005646-xhx9pzhj 4557 25 . . . cord-005646-xhx9pzhj 4558 1 Patients patient NNS cord-005646-xhx9pzhj 4558 2 and and CC cord-005646-xhx9pzhj 4558 3 methods method NNS cord-005646-xhx9pzhj 4558 4 : : : cord-005646-xhx9pzhj 4558 5 Term term NN cord-005646-xhx9pzhj 4558 6 born bear VBN cord-005646-xhx9pzhj 4558 7 babies baby NNS cord-005646-xhx9pzhj 4558 8 with with IN cord-005646-xhx9pzhj 4558 9 isolated isolate VBN cord-005646-xhx9pzhj 4558 10 oesophageal oesophageal JJ cord-005646-xhx9pzhj 4558 11 atresia atresia NN cord-005646-xhx9pzhj 4558 12 and and CC cord-005646-xhx9pzhj 4559 1 tracheo tracheo NNP cord-005646-xhx9pzhj 4559 2 - - HYPH cord-005646-xhx9pzhj 4559 3 oesophageal oesophageal JJ cord-005646-xhx9pzhj 4559 4 fistula fistula NN cord-005646-xhx9pzhj 4559 5 were be VBD cord-005646-xhx9pzhj 4559 6 included include VBN cord-005646-xhx9pzhj 4559 7 in in IN cord-005646-xhx9pzhj 4559 8 the the DT cord-005646-xhx9pzhj 4559 9 study study NN cord-005646-xhx9pzhj 4559 10 . . . cord-005646-xhx9pzhj 4560 1 The the DT cord-005646-xhx9pzhj 4560 2 total total JJ cord-005646-xhx9pzhj 4560 3 amount amount NN cord-005646-xhx9pzhj 4560 4 of of IN cord-005646-xhx9pzhj 4560 5 morphine morphine NN cord-005646-xhx9pzhj 4560 6 ( ( -LRB- cord-005646-xhx9pzhj 4560 7 /~£/kg/24 /~£/kg/24 NNP cord-005646-xhx9pzhj 4560 8 hours hour NNS cord-005646-xhx9pzhj 4560 9 ) ) -RRB- cord-005646-xhx9pzhj 4560 10 ; ; : cord-005646-xhx9pzhj 4560 11 number number NN cord-005646-xhx9pzhj 4560 12 of of IN cord-005646-xhx9pzhj 4560 13 days day NNS cord-005646-xhx9pzhj 4560 14 morphine morphine NN cord-005646-xhx9pzhj 4560 15 was be VBD cord-005646-xhx9pzhj 4560 16 given give VBN cord-005646-xhx9pzhj 4560 17 ; ; : cord-005646-xhx9pzhj 4560 18 duration duration NN cord-005646-xhx9pzhj 4560 19 of of IN cord-005646-xhx9pzhj 4560 20 artificial artificial JJ cord-005646-xhx9pzhj 4560 21 ventilation ventilation NN cord-005646-xhx9pzhj 4560 22 was be VBD cord-005646-xhx9pzhj 4560 23 evaluated evaluate VBN cord-005646-xhx9pzhj 4560 24 in in IN cord-005646-xhx9pzhj 4560 25 a a DT cord-005646-xhx9pzhj 4560 26 case case NN cord-005646-xhx9pzhj 4560 27 control control NN cord-005646-xhx9pzhj 4560 28 study study NN cord-005646-xhx9pzhj 4560 29 . . . cord-005646-xhx9pzhj 4561 1 RES RES NNP cord-005646-xhx9pzhj 4561 2 ULTS ULTS NNP cord-005646-xhx9pzhj 4561 3 : : : cord-005646-xhx9pzhj 4562 1 1985 1985 CD cord-005646-xhx9pzhj 4563 1 -1990 -1990 : cord-005646-xhx9pzhj 4563 2 1991 1991 CD cord-005646-xhx9pzhj 4564 1 -1994 -1994 JJ cord-005646-xhx9pzhj 4564 2 Central central JJ cord-005646-xhx9pzhj 4564 3 venous venous JJ cord-005646-xhx9pzhj 4564 4 catheters catheter NNS cord-005646-xhx9pzhj 4564 5 ( ( -LRB- cord-005646-xhx9pzhj 4564 6 CVC CVC NNP cord-005646-xhx9pzhj 4564 7 ) ) -RRB- cord-005646-xhx9pzhj 4564 8 have have VBP cord-005646-xhx9pzhj 4564 9 been be VBN cord-005646-xhx9pzhj 4564 10 increasingly increasingly RB cord-005646-xhx9pzhj 4564 11 used use VBN cord-005646-xhx9pzhj 4564 12 also also RB cord-005646-xhx9pzhj 4564 13 at at IN cord-005646-xhx9pzhj 4564 14 our -PRON- PRP$ cord-005646-xhx9pzhj 4564 15 PICU PICU NNP cord-005646-xhx9pzhj 4564 16 , , , cord-005646-xhx9pzhj 4564 17 University University NNP cord-005646-xhx9pzhj 4564 18 Medical Medical NNP cord-005646-xhx9pzhj 4564 19 Centre Centre NNP cord-005646-xhx9pzhj 4564 20 Ljubljana Ljubljana NNP cord-005646-xhx9pzhj 4564 21 . . . cord-005646-xhx9pzhj 4565 1 Besides besides IN cord-005646-xhx9pzhj 4565 2 advantages advantage NNS cord-005646-xhx9pzhj 4565 3 , , , cord-005646-xhx9pzhj 4565 4 the the DT cord-005646-xhx9pzhj 4565 5 CVC CVC NNP cord-005646-xhx9pzhj 4565 6 has have VBZ cord-005646-xhx9pzhj 4565 7 brought bring VBN cord-005646-xhx9pzhj 4565 8 numerous numerous JJ cord-005646-xhx9pzhj 4565 9 risks risk NNS cord-005646-xhx9pzhj 4565 10 of of IN cord-005646-xhx9pzhj 4565 11 complications complication NNS cord-005646-xhx9pzhj 4565 12 ; ; : cord-005646-xhx9pzhj 4565 13 the the DT cord-005646-xhx9pzhj 4565 14 catheter catheter NN cord-005646-xhx9pzhj 4565 15 sepsis sepsis NN cord-005646-xhx9pzhj 4565 16 occurs occur VBZ cord-005646-xhx9pzhj 4565 17 most most RBS cord-005646-xhx9pzhj 4565 18 often often RB cord-005646-xhx9pzhj 4565 19 and and CC cord-005646-xhx9pzhj 4565 20 can can MD cord-005646-xhx9pzhj 4565 21 be be VB cord-005646-xhx9pzhj 4565 22 fatal fatal JJ cord-005646-xhx9pzhj 4565 23 for for IN cord-005646-xhx9pzhj 4565 24 the the DT cord-005646-xhx9pzhj 4565 25 patient patient NN cord-005646-xhx9pzhj 4565 26 . . . cord-005646-xhx9pzhj 4566 1 For for IN cord-005646-xhx9pzhj 4566 2 example example NN cord-005646-xhx9pzhj 4566 3 , , , cord-005646-xhx9pzhj 4566 4 in in IN cord-005646-xhx9pzhj 4566 5 1995 1995 CD cord-005646-xhx9pzhj 4566 6 we -PRON- PRP cord-005646-xhx9pzhj 4566 7 dealt deal VBD cord-005646-xhx9pzhj 4566 8 with with IN cord-005646-xhx9pzhj 4566 9 400 400 CD cord-005646-xhx9pzhj 4566 10 children child NNS cord-005646-xhx9pzhj 4566 11 aged age VBN cord-005646-xhx9pzhj 4566 12 0 0 CD cord-005646-xhx9pzhj 4566 13 -12 -12 CD cord-005646-xhx9pzhj 4566 14 years year NNS cord-005646-xhx9pzhj 4566 15 or or CC cord-005646-xhx9pzhj 4566 16 in in IN cord-005646-xhx9pzhj 4566 17 other other JJ cord-005646-xhx9pzhj 4566 18 words word NNS cord-005646-xhx9pzhj 4566 19 1.14 1.14 CD cord-005646-xhx9pzhj 4566 20 CVP cvp NN cord-005646-xhx9pzhj 4566 21 per per IN cord-005646-xhx9pzhj 4566 22 a a DT cord-005646-xhx9pzhj 4566 23 child child NN cord-005646-xhx9pzhj 4566 24 treated treat VBN cord-005646-xhx9pzhj 4566 25 at at IN cord-005646-xhx9pzhj 4566 26 our -PRON- PRP$ cord-005646-xhx9pzhj 4566 27 PICU PICU NNP cord-005646-xhx9pzhj 4566 28 . . . cord-005646-xhx9pzhj 4567 1 A a DT cord-005646-xhx9pzhj 4567 2 specialized specialized JJ cord-005646-xhx9pzhj 4567 3 unit unit NN cord-005646-xhx9pzhj 4567 4 for for IN cord-005646-xhx9pzhj 4567 5 preparing prepare VBG cord-005646-xhx9pzhj 4567 6 parenteral parenteral JJ cord-005646-xhx9pzhj 4567 7 natrition natrition NN cord-005646-xhx9pzhj 4567 8 started start VBD cord-005646-xhx9pzhj 4567 9 to to TO cord-005646-xhx9pzhj 4567 10 function function VB cord-005646-xhx9pzhj 4567 11 in in IN cord-005646-xhx9pzhj 4567 12 the the DT cord-005646-xhx9pzhj 4567 13 University University NNP cord-005646-xhx9pzhj 4567 14 Medical Medical NNP cord-005646-xhx9pzhj 4567 15 Centre Centre NNP cord-005646-xhx9pzhj 4567 16 Pharmacy Pharmacy NNP cord-005646-xhx9pzhj 4567 17 in in IN cord-005646-xhx9pzhj 4567 18 1977 1977 CD cord-005646-xhx9pzhj 4567 19 . . . cord-005646-xhx9pzhj 4568 1 After after IN cord-005646-xhx9pzhj 4568 2 that that DT cord-005646-xhx9pzhj 4568 3 we -PRON- PRP cord-005646-xhx9pzhj 4568 4 equipped equip VBD cord-005646-xhx9pzhj 4568 5 a a DT cord-005646-xhx9pzhj 4568 6 special special JJ cord-005646-xhx9pzhj 4568 7 room room NN cord-005646-xhx9pzhj 4568 8 for for IN cord-005646-xhx9pzhj 4568 9 preparing prepare VBG cord-005646-xhx9pzhj 4568 10 other other JJ cord-005646-xhx9pzhj 4568 11 necessary necessary JJ cord-005646-xhx9pzhj 4568 12 infusion infusion NN cord-005646-xhx9pzhj 4568 13 mixtures mixture NNS cord-005646-xhx9pzhj 4568 14 and and CC cord-005646-xhx9pzhj 4568 15 organized organize VBD cord-005646-xhx9pzhj 4568 16 a a DT cord-005646-xhx9pzhj 4568 17 team team NN cord-005646-xhx9pzhj 4568 18 of of IN cord-005646-xhx9pzhj 4568 19 nurses nurse NNS cord-005646-xhx9pzhj 4568 20 -"catheter -"catheter RB cord-005646-xhx9pzhj 4569 1 nurses nurse NNS cord-005646-xhx9pzhj 4569 2 " " '' cord-005646-xhx9pzhj 4569 3 . . . cord-005646-xhx9pzhj 4570 1 Their -PRON- PRP$ cord-005646-xhx9pzhj 4570 2 tasks task NNS cord-005646-xhx9pzhj 4570 3 comprise comprise VBP cord-005646-xhx9pzhj 4570 4 : : : cord-005646-xhx9pzhj 4570 5 managing manage VBG cord-005646-xhx9pzhj 4570 6 CVCs CVCs NNP cord-005646-xhx9pzhj 4570 7 , , , cord-005646-xhx9pzhj 4570 8 replacing replace VBG cord-005646-xhx9pzhj 4570 9 and and CC cord-005646-xhx9pzhj 4570 10 installing instal VBG cord-005646-xhx9pzhj 4570 11 infusion infusion NN cord-005646-xhx9pzhj 4570 12 systems system NNS cord-005646-xhx9pzhj 4570 13 and and CC cord-005646-xhx9pzhj 4570 14 mixtures mixture NNS cord-005646-xhx9pzhj 4570 15 made make VBN cord-005646-xhx9pzhj 4570 16 at at IN cord-005646-xhx9pzhj 4570 17 pharmacy pharmacy NN cord-005646-xhx9pzhj 4570 18 , , , cord-005646-xhx9pzhj 4570 19 preparing prepare VBG cord-005646-xhx9pzhj 4570 20 drugs drug NNS cord-005646-xhx9pzhj 4570 21 and and CC cord-005646-xhx9pzhj 4570 22 some some DT cord-005646-xhx9pzhj 4570 23 necessary necessary JJ cord-005646-xhx9pzhj 4570 24 infusion infusion NN cord-005646-xhx9pzhj 4570 25 mixtures mixture NNS cord-005646-xhx9pzhj 4570 26 in in IN cord-005646-xhx9pzhj 4570 27 special special JJ cord-005646-xhx9pzhj 4570 28 room room NN cord-005646-xhx9pzhj 4570 29 , , , cord-005646-xhx9pzhj 4570 30 permanent permanent JJ cord-005646-xhx9pzhj 4570 31 training training NN cord-005646-xhx9pzhj 4570 32 and and CC cord-005646-xhx9pzhj 4570 33 co co NN cord-005646-xhx9pzhj 4570 34 - - NN cord-005646-xhx9pzhj 4570 35 operation operation NN cord-005646-xhx9pzhj 4570 36 with with IN cord-005646-xhx9pzhj 4570 37 related related JJ cord-005646-xhx9pzhj 4570 38 disciplines discipline NNS cord-005646-xhx9pzhj 4570 39 , , , cord-005646-xhx9pzhj 4570 40 pharmacy pharmacy NN cord-005646-xhx9pzhj 4570 41 , , , cord-005646-xhx9pzhj 4570 42 epidemiology epidemiology NN cord-005646-xhx9pzhj 4570 43 , , , cord-005646-xhx9pzhj 4570 44 microbiology microbiology NN cord-005646-xhx9pzhj 4570 45 , , , cord-005646-xhx9pzhj 4570 46 etc etc FW cord-005646-xhx9pzhj 4570 47 . . . cord-005646-xhx9pzhj 4571 1 All all DT cord-005646-xhx9pzhj 4571 2 registered register VBN cord-005646-xhx9pzhj 4571 3 nurses nurse NNS cord-005646-xhx9pzhj 4571 4 at at IN cord-005646-xhx9pzhj 4571 5 PICU PICU NNP cord-005646-xhx9pzhj 4571 6 have have VBP cord-005646-xhx9pzhj 4571 7 been be VBN cord-005646-xhx9pzhj 4571 8 trained train VBN cord-005646-xhx9pzhj 4571 9 for for IN cord-005646-xhx9pzhj 4571 10 this this DT cord-005646-xhx9pzhj 4571 11 work work NN cord-005646-xhx9pzhj 4571 12 . . . cord-005646-xhx9pzhj 4572 1 The the DT cord-005646-xhx9pzhj 4572 2 routine routine NN cord-005646-xhx9pzhj 4572 3 is be VBZ cord-005646-xhx9pzhj 4572 4 as as IN cord-005646-xhx9pzhj 4572 5 follows follow VBZ cord-005646-xhx9pzhj 4572 6 : : : cord-005646-xhx9pzhj 4572 7 in in IN cord-005646-xhx9pzhj 4572 8 the the DT cord-005646-xhx9pzhj 4572 9 morningafter morningafter NN cord-005646-xhx9pzhj 4572 10 the the DT cord-005646-xhx9pzhj 4572 11 doctor doctor NN cord-005646-xhx9pzhj 4572 12 's 's POS cord-005646-xhx9pzhj 4572 13 visit visit NN cord-005646-xhx9pzhj 4572 14 , , , cord-005646-xhx9pzhj 4572 15 we -PRON- PRP cord-005646-xhx9pzhj 4572 16 first first RB cord-005646-xhx9pzhj 4572 17 check check VBP cord-005646-xhx9pzhj 4572 18 the the DT cord-005646-xhx9pzhj 4572 19 CVC CVC NNP cord-005646-xhx9pzhj 4572 20 and and CC cord-005646-xhx9pzhj 4572 21 change change VB cord-005646-xhx9pzhj 4572 22 the the DT cord-005646-xhx9pzhj 4572 23 dressings dressing NNS cord-005646-xhx9pzhj 4572 24 ; ; : cord-005646-xhx9pzhj 4572 25 according accord VBG cord-005646-xhx9pzhj 4572 26 to to IN cord-005646-xhx9pzhj 4572 27 the the DT cord-005646-xhx9pzhj 4572 28 nurse nurse NN cord-005646-xhx9pzhj 4572 29 's 's POS cord-005646-xhx9pzhj 4572 30 observations observation NNS cord-005646-xhx9pzhj 4572 31 , , , cord-005646-xhx9pzhj 4572 32 the the DT cord-005646-xhx9pzhj 4572 33 doctor doctor NN cord-005646-xhx9pzhj 4572 34 decides decide VBZ cord-005646-xhx9pzhj 4572 35 whether whether IN cord-005646-xhx9pzhj 4572 36 there there EX cord-005646-xhx9pzhj 4572 37 is be VBZ cord-005646-xhx9pzhj 4572 38 a a DT cord-005646-xhx9pzhj 4572 39 need need NN cord-005646-xhx9pzhj 4572 40 to to TO cord-005646-xhx9pzhj 4572 41 remove remove VB cord-005646-xhx9pzhj 4572 42 or or CC cord-005646-xhx9pzhj 4572 43 replace replace VB cord-005646-xhx9pzhj 4572 44 the the DT cord-005646-xhx9pzhj 4572 45 CVC CVC NNP cord-005646-xhx9pzhj 4572 46 . . . cord-005646-xhx9pzhj 4573 1 If if IN cord-005646-xhx9pzhj 4573 2 the the DT cord-005646-xhx9pzhj 4573 3 catheter catheter NN cord-005646-xhx9pzhj 4573 4 site site NN cord-005646-xhx9pzhj 4573 5 is be VBZ cord-005646-xhx9pzhj 4573 6 inflamed inflame VBN cord-005646-xhx9pzhj 4573 7 , , , cord-005646-xhx9pzhj 4573 8 swollen swollen JJ cord-005646-xhx9pzhj 4573 9 , , , cord-005646-xhx9pzhj 4573 10 or or CC cord-005646-xhx9pzhj 4573 11 purulent purulent JJ cord-005646-xhx9pzhj 4573 12 , , , cord-005646-xhx9pzhj 4573 13 a a DT cord-005646-xhx9pzhj 4573 14 swab swab NN cord-005646-xhx9pzhj 4573 15 is be VBZ cord-005646-xhx9pzhj 4573 16 taken take VBN cord-005646-xhx9pzhj 4573 17 for for IN cord-005646-xhx9pzhj 4573 18 microbiological microbiological JJ cord-005646-xhx9pzhj 4573 19 culture culture NN cord-005646-xhx9pzhj 4573 20 and and CC cord-005646-xhx9pzhj 4573 21 the the DT cord-005646-xhx9pzhj 4573 22 area area NN cord-005646-xhx9pzhj 4573 23 cleaned clean VBD cord-005646-xhx9pzhj 4573 24 . . . cord-005646-xhx9pzhj 4574 1 In in IN cord-005646-xhx9pzhj 4574 2 case case NN cord-005646-xhx9pzhj 4574 3 of of IN cord-005646-xhx9pzhj 4574 4 systemic systemic JJ cord-005646-xhx9pzhj 4574 5 infection infection NN cord-005646-xhx9pzhj 4574 6 signs sign NNS cord-005646-xhx9pzhj 4574 7 , , , cord-005646-xhx9pzhj 4574 8 CVC CVC NNP cord-005646-xhx9pzhj 4574 9 has have VBZ cord-005646-xhx9pzhj 4574 10 to to TO cord-005646-xhx9pzhj 4574 11 be be VB cord-005646-xhx9pzhj 4574 12 replaced replace VBN cord-005646-xhx9pzhj 4574 13 , , , cord-005646-xhx9pzhj 4574 14 blood blood NN cord-005646-xhx9pzhj 4574 15 culture culture NN cord-005646-xhx9pzhj 4574 16 taken take VBN cord-005646-xhx9pzhj 4574 17 and and CC cord-005646-xhx9pzhj 4574 18 the the DT cord-005646-xhx9pzhj 4574 19 infection infection NN cord-005646-xhx9pzhj 4574 20 treated treat VBN cord-005646-xhx9pzhj 4574 21 with with IN cord-005646-xhx9pzhj 4574 22 antibiotics antibiotic NNS cord-005646-xhx9pzhj 4574 23 . . . cord-005646-xhx9pzhj 4575 1 The the DT cord-005646-xhx9pzhj 4575 2 dressings dressing NNS cord-005646-xhx9pzhj 4575 3 are be VBP cord-005646-xhx9pzhj 4575 4 always always RB cord-005646-xhx9pzhj 4575 5 changed change VBN cord-005646-xhx9pzhj 4575 6 by by IN cord-005646-xhx9pzhj 4575 7 two two CD cord-005646-xhx9pzhj 4575 8 TMcatheter TMcatheter NNP cord-005646-xhx9pzhj 4575 9 nurses nurse NNS cord-005646-xhx9pzhj 4575 10 together together RB cord-005646-xhx9pzhj 4575 11 . . . cord-005646-xhx9pzhj 4576 1 Afterwards afterwards RB cord-005646-xhx9pzhj 4576 2 the the DT cord-005646-xhx9pzhj 4576 3 infusion infusion NN cord-005646-xhx9pzhj 4576 4 mixtures mixture NNS cord-005646-xhx9pzhj 4576 5 for for IN cord-005646-xhx9pzhj 4576 6 the the DT cord-005646-xhx9pzhj 4576 7 next next JJ cord-005646-xhx9pzhj 4576 8 24 24 CD cord-005646-xhx9pzhj 4576 9 hours hour NNS cord-005646-xhx9pzhj 4576 10 are be VBP cord-005646-xhx9pzhj 4576 11 prepared prepare VBN cord-005646-xhx9pzhj 4576 12 for for IN cord-005646-xhx9pzhj 4576 13 each each DT cord-005646-xhx9pzhj 4576 14 child child NN cord-005646-xhx9pzhj 4576 15 . . . cord-005646-xhx9pzhj 4577 1 The the DT cord-005646-xhx9pzhj 4577 2 infusion infusion NN cord-005646-xhx9pzhj 4577 3 mixtures mixture NNS cord-005646-xhx9pzhj 4577 4 which which WDT cord-005646-xhx9pzhj 4577 5 will will MD cord-005646-xhx9pzhj 4577 6 not not RB cord-005646-xhx9pzhj 4577 7 be be VB cord-005646-xhx9pzhj 4577 8 used use VBN cord-005646-xhx9pzhj 4577 9 immediately immediately RB cord-005646-xhx9pzhj 4577 10 are be VBP cord-005646-xhx9pzhj 4577 11 kept keep VBN cord-005646-xhx9pzhj 4577 12 on on IN cord-005646-xhx9pzhj 4577 13 +4 +4 HYPH cord-005646-xhx9pzhj 4577 14 ° ° NN cord-005646-xhx9pzhj 4577 15 C c NN cord-005646-xhx9pzhj 4577 16 ; ; : cord-005646-xhx9pzhj 4577 17 before before IN cord-005646-xhx9pzhj 4577 18 application application NN cord-005646-xhx9pzhj 4577 19 they -PRON- PRP cord-005646-xhx9pzhj 4577 20 are be VBP cord-005646-xhx9pzhj 4577 21 , , , cord-005646-xhx9pzhj 4577 22 of of IN cord-005646-xhx9pzhj 4577 23 course course NN cord-005646-xhx9pzhj 4577 24 , , , cord-005646-xhx9pzhj 4577 25 warmed warm VBN cord-005646-xhx9pzhj 4577 26 to to IN cord-005646-xhx9pzhj 4577 27 at at IN cord-005646-xhx9pzhj 4577 28 least least JJS cord-005646-xhx9pzhj 4577 29 room room NN cord-005646-xhx9pzhj 4577 30 temperature temperature NN cord-005646-xhx9pzhj 4577 31 . . . cord-005646-xhx9pzhj 4578 1 Finally finally RB cord-005646-xhx9pzhj 4578 2 the the DT cord-005646-xhx9pzhj 4578 3 " " `` cord-005646-xhx9pzhj 4578 4 catheter catheter NN cord-005646-xhx9pzhj 4578 5 nurse nurse NN cord-005646-xhx9pzhj 4578 6 " " '' cord-005646-xhx9pzhj 4578 7 supplies supply VBZ cord-005646-xhx9pzhj 4578 8 the the DT cord-005646-xhx9pzhj 4578 9 CVC CVC NNP cord-005646-xhx9pzhj 4578 10 with with IN cord-005646-xhx9pzhj 4578 11 new new JJ cord-005646-xhx9pzhj 4578 12 infusion infusion NN cord-005646-xhx9pzhj 4578 13 mixtures mixture NNS cord-005646-xhx9pzhj 4578 14 made make VBN cord-005646-xhx9pzhj 4578 15 at at IN cord-005646-xhx9pzhj 4578 16 our -PRON- PRP$ cord-005646-xhx9pzhj 4578 17 pharmacy pharmacy NN cord-005646-xhx9pzhj 4578 18 . . . cord-005646-xhx9pzhj 4579 1 Our -PRON- PRP$ cord-005646-xhx9pzhj 4579 2 observations observation NNS cord-005646-xhx9pzhj 4579 3 show show VBP cord-005646-xhx9pzhj 4579 4 that that IN cord-005646-xhx9pzhj 4579 5 such such JJ cord-005646-xhx9pzhj 4579 6 work work NN cord-005646-xhx9pzhj 4579 7 requires require VBZ cord-005646-xhx9pzhj 4579 8 responsibility responsibility NN cord-005646-xhx9pzhj 4579 9 and and CC cord-005646-xhx9pzhj 4579 10 is be VBZ cord-005646-xhx9pzhj 4579 11 demanding demand VBG cord-005646-xhx9pzhj 4579 12 ; ; : cord-005646-xhx9pzhj 4579 13 but but CC cord-005646-xhx9pzhj 4579 14 our -PRON- PRP$ cord-005646-xhx9pzhj 4579 15 pemanent pemanent JJ cord-005646-xhx9pzhj 4579 16 care care NN cord-005646-xhx9pzhj 4579 17 lessens lessen VBZ cord-005646-xhx9pzhj 4579 18 the the DT cord-005646-xhx9pzhj 4579 19 number number NN cord-005646-xhx9pzhj 4579 20 of of IN cord-005646-xhx9pzhj 4579 21 complications complication NNS cord-005646-xhx9pzhj 4579 22 . . . cord-005646-xhx9pzhj 4580 1 Thus thus RB cord-005646-xhx9pzhj 4580 2 the the DT cord-005646-xhx9pzhj 4580 3 described describe VBN cord-005646-xhx9pzhj 4580 4 scheme scheme NN cord-005646-xhx9pzhj 4580 5 fulfilled fulfil VBD cord-005646-xhx9pzhj 4580 6 our -PRON- PRP$ cord-005646-xhx9pzhj 4580 7 expectations expectation NNS cord-005646-xhx9pzhj 4580 8 . . . cord-005646-xhx9pzhj 4581 1 Perl-0perative perl-0perative JJ cord-005646-xhx9pzhj 4581 2 management management NN cord-005646-xhx9pzhj 4581 3 of of IN cord-005646-xhx9pzhj 4581 4 neonates neonate NNS cord-005646-xhx9pzhj 4581 5 with with IN cord-005646-xhx9pzhj 4581 6 Hypoplastic Hypoplastic NNP cord-005646-xhx9pzhj 4581 7 Left Left NNP cord-005646-xhx9pzhj 4581 8 Heart Heart NNP cord-005646-xhx9pzhj 4581 9 Syndrome Syndrome NNP cord-005646-xhx9pzhj 4581 10 MUIR MUIR NNP cord-005646-xhx9pzhj 4581 11 Warren Warren NNP cord-005646-xhx9pzhj 4581 12 , , , cord-005646-xhx9pzhj 4581 13 BLONDEL BLONDEL NNP cord-005646-xhx9pzhj 4581 14 Maryse Maryse NNP cord-005646-xhx9pzhj 4581 15 , , , cord-005646-xhx9pzhj 4581 16 FOLTZ FOLTZ NNP cord-005646-xhx9pzhj 4581 17 Rhonda Rhonda NNP cord-005646-xhx9pzhj 4581 18 , , , cord-005646-xhx9pzhj 4581 19 FARINE FARINE NNP cord-005646-xhx9pzhj 4581 20 Martine Martine NNP cord-005646-xhx9pzhj 4581 21 , , , cord-005646-xhx9pzhj 4581 22 ICU ICU NNP cord-005646-xhx9pzhj 4581 23 nurses nurse NNS cord-005646-xhx9pzhj 4581 24 , , , cord-005646-xhx9pzhj 4581 25 The the DT cord-005646-xhx9pzhj 4581 26 Aldo Aldo NNP cord-005646-xhx9pzhj 4581 27 Castaneda Castaneda NNP cord-005646-xhx9pzhj 4581 28 Institute Institute NNP cord-005646-xhx9pzhj 4581 29 , , , cord-005646-xhx9pzhj 4581 30 Clinique Clinique NNP cord-005646-xhx9pzhj 4581 31 de de NNP cord-005646-xhx9pzhj 4581 32 Genolier Genolier NNP cord-005646-xhx9pzhj 4581 33 , , , cord-005646-xhx9pzhj 4581 34 Switzerland Switzerland NNP cord-005646-xhx9pzhj 4582 1 Both both DT cord-005646-xhx9pzhj 4582 2 the the DT cord-005646-xhx9pzhj 4582 3 pre pre JJ cord-005646-xhx9pzhj 4582 4 - - JJ cord-005646-xhx9pzhj 4582 5 operative operative JJ cord-005646-xhx9pzhj 4582 6 and and CC cord-005646-xhx9pzhj 4582 7 post post JJ cord-005646-xhx9pzhj 4582 8 - - JJ cord-005646-xhx9pzhj 4582 9 operative operative JJ cord-005646-xhx9pzhj 4582 10 physiology physiology NN cord-005646-xhx9pzhj 4582 11 of of IN cord-005646-xhx9pzhj 4582 12 patient patient NN cord-005646-xhx9pzhj 4582 13 with with IN cord-005646-xhx9pzhj 4582 14 Hypoplastic Hypoplastic NNP cord-005646-xhx9pzhj 4582 15 Left Left NNP cord-005646-xhx9pzhj 4582 16 Heart Heart NNP cord-005646-xhx9pzhj 4582 17 Syndrome Syndrome NNP cord-005646-xhx9pzhj 4582 18 is be VBZ cord-005646-xhx9pzhj 4582 19 critically critically RB cord-005646-xhx9pzhj 4582 20 determined determine VBN cord-005646-xhx9pzhj 4582 21 by by IN cord-005646-xhx9pzhj 4582 22 the the DT cord-005646-xhx9pzhj 4582 23 puhnonary puhnonary JJ cord-005646-xhx9pzhj 4582 24 - - HYPH cord-005646-xhx9pzhj 4582 25 tosystemic tosystemic JJ cord-005646-xhx9pzhj 4582 26 resistance resistance NN cord-005646-xhx9pzhj 4582 27 ratio ratio NN cord-005646-xhx9pzhj 4582 28 . . . cord-005646-xhx9pzhj 4583 1 A a DT cord-005646-xhx9pzhj 4583 2 high high JJ cord-005646-xhx9pzhj 4583 3 ratio ratio NN cord-005646-xhx9pzhj 4583 4 results result NNS cord-005646-xhx9pzhj 4583 5 in in IN cord-005646-xhx9pzhj 4583 6 minimum minimum JJ cord-005646-xhx9pzhj 4583 7 volume volume NN cord-005646-xhx9pzhj 4583 8 work work NN cord-005646-xhx9pzhj 4583 9 for for IN cord-005646-xhx9pzhj 4583 10 the the DT cord-005646-xhx9pzhj 4583 11 right right JJ cord-005646-xhx9pzhj 4583 12 ventricle ventricle NN cord-005646-xhx9pzhj 4583 13 but but CC cord-005646-xhx9pzhj 4583 14 is be VBZ cord-005646-xhx9pzhj 4583 15 at at IN cord-005646-xhx9pzhj 4583 16 the the DT cord-005646-xhx9pzhj 4583 17 expense expense NN cord-005646-xhx9pzhj 4583 18 of of IN cord-005646-xhx9pzhj 4583 19 important important JJ cord-005646-xhx9pzhj 4583 20 hypoxemia hypoxemia NN cord-005646-xhx9pzhj 4583 21 . . . cord-005646-xhx9pzhj 4584 1 A a DT cord-005646-xhx9pzhj 4584 2 low low JJ cord-005646-xhx9pzhj 4584 3 ratio ratio NN cord-005646-xhx9pzhj 4584 4 is be VBZ cord-005646-xhx9pzhj 4584 5 reflected reflect VBN cord-005646-xhx9pzhj 4584 6 in in IN cord-005646-xhx9pzhj 4584 7 minimum minimum JJ cord-005646-xhx9pzhj 4584 8 hypoxemia hypoxemia NN cord-005646-xhx9pzhj 4584 9 but but CC cord-005646-xhx9pzhj 4584 10 an an DT cord-005646-xhx9pzhj 4584 11 unfavorable unfavorable JJ cord-005646-xhx9pzhj 4584 12 increase increase NN cord-005646-xhx9pzhj 4584 13 in in IN cord-005646-xhx9pzhj 4584 14 excess excess JJ cord-005646-xhx9pzhj 4584 15 ventricular ventricular JJ cord-005646-xhx9pzhj 4584 16 volume volume NN cord-005646-xhx9pzhj 4584 17 work work NN cord-005646-xhx9pzhj 4584 18 . . . cord-005646-xhx9pzhj 4585 1 A a DT cord-005646-xhx9pzhj 4585 2 resistance resistance NN cord-005646-xhx9pzhj 4585 3 ratio ratio NN cord-005646-xhx9pzhj 4585 4 of of IN cord-005646-xhx9pzhj 4585 5 approximately approximately RB cord-005646-xhx9pzhj 4585 6 1 1 CD cord-005646-xhx9pzhj 4585 7 results result NNS cord-005646-xhx9pzhj 4585 8 in in IN cord-005646-xhx9pzhj 4585 9 an an DT cord-005646-xhx9pzhj 4585 10 arterial arterial JJ cord-005646-xhx9pzhj 4585 11 oxygen oxygen NN cord-005646-xhx9pzhj 4585 12 saturation saturation NN cord-005646-xhx9pzhj 4585 13 of of IN cord-005646-xhx9pzhj 4585 14 75 75 CD cord-005646-xhx9pzhj 4585 15 % % NN cord-005646-xhx9pzhj 4585 16 -80 -80 NNP cord-005646-xhx9pzhj 4585 17 % % NN cord-005646-xhx9pzhj 4585 18 , , , cord-005646-xhx9pzhj 4585 19 a a DT cord-005646-xhx9pzhj 4585 20 Qp Qp NNP cord-005646-xhx9pzhj 4585 21 / / SYM cord-005646-xhx9pzhj 4585 22 Qs Qs NNP cord-005646-xhx9pzhj 4585 23 of of IN cord-005646-xhx9pzhj 4585 24 1 1 CD cord-005646-xhx9pzhj 4585 25 , , , cord-005646-xhx9pzhj 4585 26 and and CC cord-005646-xhx9pzhj 4585 27 ventricular ventricular JJ cord-005646-xhx9pzhj 4585 28 volume volume NN cord-005646-xhx9pzhj 4585 29 work work NN cord-005646-xhx9pzhj 4585 30 only only RB cord-005646-xhx9pzhj 4585 31 twice twice PDT cord-005646-xhx9pzhj 4585 32 normal normal JJ cord-005646-xhx9pzhj 4585 33 . . . cord-005646-xhx9pzhj 4586 1 This this DT cord-005646-xhx9pzhj 4586 2 latter latter JJ cord-005646-xhx9pzhj 4586 3 physiology physiology NN cord-005646-xhx9pzhj 4586 4 appears appear VBZ cord-005646-xhx9pzhj 4586 5 best well RBS cord-005646-xhx9pzhj 4586 6 for for IN cord-005646-xhx9pzhj 4586 7 oxygen oxygen NN cord-005646-xhx9pzhj 4586 8 delivery delivery NN cord-005646-xhx9pzhj 4586 9 and and CC cord-005646-xhx9pzhj 4586 10 systemic systemic JJ cord-005646-xhx9pzhj 4586 11 perfusion perfusion NN cord-005646-xhx9pzhj 4586 12 with with IN cord-005646-xhx9pzhj 4586 13 tolerable tolerable JJ cord-005646-xhx9pzhj 4586 14 volume volume NN cord-005646-xhx9pzhj 4586 15 work work NN cord-005646-xhx9pzhj 4586 16 . . . cord-005646-xhx9pzhj 4587 1 Carbon carbon NN cord-005646-xhx9pzhj 4587 2 dioxide dioxide NN cord-005646-xhx9pzhj 4587 3 ( ( -LRB- cord-005646-xhx9pzhj 4587 4 CO2 CO2 NNP cord-005646-xhx9pzhj 4587 5 ) ) -RRB- cord-005646-xhx9pzhj 4587 6 in in IN cord-005646-xhx9pzhj 4587 7 the the DT cord-005646-xhx9pzhj 4587 8 inspired inspire VBN cord-005646-xhx9pzhj 4587 9 gas gas NN cord-005646-xhx9pzhj 4587 10 is be VBZ cord-005646-xhx9pzhj 4587 11 known know VBN cord-005646-xhx9pzhj 4587 12 to to TO cord-005646-xhx9pzhj 4587 13 increase increase VB cord-005646-xhx9pzhj 4587 14 pulmonary pulmonary JJ cord-005646-xhx9pzhj 4587 15 vascular vascular JJ cord-005646-xhx9pzhj 4587 16 resistance resistance NN cord-005646-xhx9pzhj 4587 17 without without IN cord-005646-xhx9pzhj 4587 18 significantly significantly RB cord-005646-xhx9pzhj 4587 19 influencing influence VBG cord-005646-xhx9pzhj 4587 20 systemic systemic JJ cord-005646-xhx9pzhj 4587 21 resistance resistance NN cord-005646-xhx9pzhj 4587 22 in in IN cord-005646-xhx9pzhj 4587 23 the the DT cord-005646-xhx9pzhj 4587 24 range range NN cord-005646-xhx9pzhj 4587 25 of of IN cord-005646-xhx9pzhj 4587 26 1 1 CD cord-005646-xhx9pzhj 4587 27 to to TO cord-005646-xhx9pzhj 4587 28 20 20 CD cord-005646-xhx9pzhj 4587 29 tort tort NN cord-005646-xhx9pzhj 4587 30 partial partial JJ cord-005646-xhx9pzhj 4587 31 pressure pressure NN cord-005646-xhx9pzhj 4587 32 . . . cord-005646-xhx9pzhj 4588 1 Hyperventilation hyperventilation NN cord-005646-xhx9pzhj 4588 2 with with IN cord-005646-xhx9pzhj 4588 3 no no DT cord-005646-xhx9pzhj 4588 4 CO2 co2 NN cord-005646-xhx9pzhj 4588 5 in in IN cord-005646-xhx9pzhj 4588 6 inspired inspire VBN cord-005646-xhx9pzhj 4588 7 gas gas NN cord-005646-xhx9pzhj 4588 8 decreases decrease VBZ cord-005646-xhx9pzhj 4588 9 pulmonary pulmonary JJ cord-005646-xhx9pzhj 4588 10 vascular vascular JJ cord-005646-xhx9pzhj 4588 11 resistance resistance NN cord-005646-xhx9pzhj 4588 12 . . . cord-005646-xhx9pzhj 4589 1 Thus thus RB cord-005646-xhx9pzhj 4589 2 , , , cord-005646-xhx9pzhj 4589 3 managing manage VBG cord-005646-xhx9pzhj 4589 4 CO2 CO2 NNP cord-005646-xhx9pzhj 4589 5 may may MD cord-005646-xhx9pzhj 4589 6 be be VB cord-005646-xhx9pzhj 4589 7 useful useful JJ cord-005646-xhx9pzhj 4589 8 to to TO cord-005646-xhx9pzhj 4589 9 modulate modulate VB cord-005646-xhx9pzhj 4589 10 the the DT cord-005646-xhx9pzhj 4589 11 pulmonary pulmonary NN cord-005646-xhx9pzhj 4589 12 - - HYPH cord-005646-xhx9pzhj 4589 13 to to IN cord-005646-xhx9pzhj 4589 14 - - HYPH cord-005646-xhx9pzhj 4589 15 systemic systemic JJ cord-005646-xhx9pzhj 4589 16 resistance resistance NN cord-005646-xhx9pzhj 4589 17 ratio ratio NN cord-005646-xhx9pzhj 4589 18 , , , cord-005646-xhx9pzhj 4589 19 in in IN cord-005646-xhx9pzhj 4589 20 the the DT cord-005646-xhx9pzhj 4589 21 tast tast NNP cord-005646-xhx9pzhj 4589 22 16 16 CD cord-005646-xhx9pzhj 4589 23 months month NNS cord-005646-xhx9pzhj 4589 24 , , , cord-005646-xhx9pzhj 4589 25 20 20 CD cord-005646-xhx9pzhj 4589 26 patients patient NNS cord-005646-xhx9pzhj 4589 27 with with IN cord-005646-xhx9pzhj 4589 28 Hypoplastic Hypoplastic NNP cord-005646-xhx9pzhj 4589 29 Left Left NNP cord-005646-xhx9pzhj 4589 30 Heart Heart NNP cord-005646-xhx9pzhj 4589 31 Syndrome Syndrome NNP cord-005646-xhx9pzhj 4589 32 were be VBD cord-005646-xhx9pzhj 4589 33 managed manage VBN cord-005646-xhx9pzhj 4589 34 by by IN cord-005646-xhx9pzhj 4589 35 a a DT cord-005646-xhx9pzhj 4589 36 Norwood Norwood NNP cord-005646-xhx9pzhj 4589 37 procedur procedur NN cord-005646-xhx9pzhj 4589 38 e. e. NNP cord-005646-xhx9pzhj 4589 39 10 10 CD cord-005646-xhx9pzhj 4589 40 patients patient NNS cord-005646-xhx9pzhj 4589 41 with with IN cord-005646-xhx9pzhj 4589 42 endotracheal endotracheal NN cord-005646-xhx9pzhj 4589 43 entubation entubation NN cord-005646-xhx9pzhj 4589 44 pre pre NN cord-005646-xhx9pzhj 4589 45 - - JJ cord-005646-xhx9pzhj 4589 46 operatively operatively RB cord-005646-xhx9pzhj 4589 47 had have VBD cord-005646-xhx9pzhj 4589 48 CO2 co2 NN cord-005646-xhx9pzhj 4589 49 added add VBN cord-005646-xhx9pzhj 4589 50 to to IN cord-005646-xhx9pzhj 4589 51 inspired inspire VBN cord-005646-xhx9pzhj 4589 52 gas gas NN cord-005646-xhx9pzhj 4589 53 to to TO cord-005646-xhx9pzhj 4589 54 modulate modulate VB cord-005646-xhx9pzhj 4589 55 the the DT cord-005646-xhx9pzhj 4589 56 pulmonary pulmonary NN cord-005646-xhx9pzhj 4589 57 - - HYPH cord-005646-xhx9pzhj 4589 58 to to IN cord-005646-xhx9pzhj 4589 59 - - HYPH cord-005646-xhx9pzhj 4589 60 systemic systemic JJ cord-005646-xhx9pzhj 4589 61 flow flow NN cord-005646-xhx9pzhj 4589 62 ratio ratio NN cord-005646-xhx9pzhj 4589 63 . . . cord-005646-xhx9pzhj 4590 1 17 17 CD cord-005646-xhx9pzhj 4590 2 patients patient NNS cord-005646-xhx9pzhj 4590 3 had have VBD cord-005646-xhx9pzhj 4590 4 CO2 CO2 NNP cord-005646-xhx9pzhj 4590 5 added add VBN cord-005646-xhx9pzhj 4590 6 to to IN cord-005646-xhx9pzhj 4590 7 inspired inspire VBN cord-005646-xhx9pzhj 4590 8 gas gas NN cord-005646-xhx9pzhj 4590 9 post post NN cord-005646-xhx9pzhj 4590 10 - - JJ cord-005646-xhx9pzhj 4590 11 operatively operatively RB cord-005646-xhx9pzhj 4590 12 . . . cord-005646-xhx9pzhj 4591 1 All all DT cord-005646-xhx9pzhj 4591 2 but but IN cord-005646-xhx9pzhj 4591 3 1 1 CD cord-005646-xhx9pzhj 4591 4 patient patient NN cord-005646-xhx9pzhj 4591 5 had have VBD cord-005646-xhx9pzhj 4591 6 characteristically characteristically RB cord-005646-xhx9pzhj 4591 7 large large JJ cord-005646-xhx9pzhj 4591 8 pulmonaary pulmonaary NN cord-005646-xhx9pzhj 4591 9 - - HYPH cord-005646-xhx9pzhj 4591 10 to to IN cord-005646-xhx9pzhj 4591 11 - - HYPH cord-005646-xhx9pzhj 4591 12 systemic systemic JJ cord-005646-xhx9pzhj 4591 13 flow flow NN cord-005646-xhx9pzhj 4591 14 ratio ratio NN cord-005646-xhx9pzhj 4591 15 with with IN cord-005646-xhx9pzhj 4591 16 oxygen oxygen NN cord-005646-xhx9pzhj 4591 17 saturation saturation NN cord-005646-xhx9pzhj 4592 1 mean mean VB cord-005646-xhx9pzhj 4592 2 90 90 CD cord-005646-xhx9pzhj 4592 3 % % NN cord-005646-xhx9pzhj 4592 4 preoperatively preoperatively NN cord-005646-xhx9pzhj 4592 5 , , , cord-005646-xhx9pzhj 4592 6 even even RB cord-005646-xhx9pzhj 4592 7 in in IN cord-005646-xhx9pzhj 4592 8 those those DT cord-005646-xhx9pzhj 4592 9 patients patient NNS cord-005646-xhx9pzhj 4592 10 receiving receive VBG cord-005646-xhx9pzhj 4592 11 CO2 CO2 NNP cord-005646-xhx9pzhj 4592 12 , , , cord-005646-xhx9pzhj 4592 13 CO2 CO2 NNP cord-005646-xhx9pzhj 4592 14 was be VBD cord-005646-xhx9pzhj 4592 15 accompanied accompany VBN cord-005646-xhx9pzhj 4592 16 by by IN cord-005646-xhx9pzhj 4592 17 elimination elimination NN cord-005646-xhx9pzhj 4592 18 of of IN cord-005646-xhx9pzhj 4592 19 metabolic metabolic JJ cord-005646-xhx9pzhj 4592 20 acidosis acidosis NN cord-005646-xhx9pzhj 4592 21 pre pre JJ cord-005646-xhx9pzhj 4592 22 - - VBZ cord-005646-xhx9pzhj 4592 23 operatively operatively RB cord-005646-xhx9pzhj 4592 24 . . . cord-005646-xhx9pzhj 4593 1 The the DT cord-005646-xhx9pzhj 4593 2 most most RBS cord-005646-xhx9pzhj 4593 3 comlnon comlnon JJ cord-005646-xhx9pzhj 4593 4 partial partial JJ cord-005646-xhx9pzhj 4593 5 pressure pressure NN cord-005646-xhx9pzhj 4593 6 of of IN cord-005646-xhx9pzhj 4593 7 CO2 CO2 NNP cord-005646-xhx9pzhj 4593 8 added add VBD cord-005646-xhx9pzhj 4593 9 post post RB cord-005646-xhx9pzhj 4593 10 - - NN cord-005646-xhx9pzhj 4593 11 operatively operatively RB cord-005646-xhx9pzhj 4593 12 was be VBD cord-005646-xhx9pzhj 4593 13 14 14 CD cord-005646-xhx9pzhj 4593 14 torr torr NNS cord-005646-xhx9pzhj 4593 15 . . . cord-005646-xhx9pzhj 4594 1 pO2 pO2 NNP cord-005646-xhx9pzhj 4594 2 ranged range VBD cord-005646-xhx9pzhj 4594 3 from from IN cord-005646-xhx9pzhj 4594 4 25 25 CD cord-005646-xhx9pzhj 4594 5 mmHg mmHg NNS cord-005646-xhx9pzhj 4594 6 to to IN cord-005646-xhx9pzhj 4594 7 40 40 CD cord-005646-xhx9pzhj 4594 8 mmHg mmHg NNS cord-005646-xhx9pzhj 4594 9 . . . cord-005646-xhx9pzhj 4595 1 All all DT cord-005646-xhx9pzhj 4595 2 surviving survive VBG cord-005646-xhx9pzhj 4595 3 patients patient NNS cord-005646-xhx9pzhj 4595 4 developed develop VBD cord-005646-xhx9pzhj 4595 5 a a DT cord-005646-xhx9pzhj 4595 6 metabolic metabolic JJ cord-005646-xhx9pzhj 4595 7 alkalosis alkalosis NN cord-005646-xhx9pzhj 4595 8 ( ( -LRB- cord-005646-xhx9pzhj 4595 9 10 10 CD cord-005646-xhx9pzhj 4595 10 mean mean NN cord-005646-xhx9pzhj 4595 11 ) ) -RRB- cord-005646-xhx9pzhj 4595 12 when when WRB cord-005646-xhx9pzhj 4595 13 treated treat VBN cord-005646-xhx9pzhj 4595 14 with with IN cord-005646-xhx9pzhj 4595 15 CO2 CO2 NNP cord-005646-xhx9pzhj 4595 16 . . . cord-005646-xhx9pzhj 4596 1 There there EX cord-005646-xhx9pzhj 4596 2 were be VBD cord-005646-xhx9pzhj 4596 3 4 4 CD cord-005646-xhx9pzhj 4596 4 deaths death NNS cord-005646-xhx9pzhj 4596 5 , , , cord-005646-xhx9pzhj 4596 6 one one CD cord-005646-xhx9pzhj 4596 7 from from IN cord-005646-xhx9pzhj 4596 8 drug drug NN cord-005646-xhx9pzhj 4596 9 toxicity toxicity NN cord-005646-xhx9pzhj 4596 10 , , , cord-005646-xhx9pzhj 4596 11 one one CD cord-005646-xhx9pzhj 4596 12 from from IN cord-005646-xhx9pzhj 4596 13 excessive excessive JJ cord-005646-xhx9pzhj 4596 14 post post JJ cord-005646-xhx9pzhj 4596 15 - - JJ cord-005646-xhx9pzhj 4596 16 operative operative JJ cord-005646-xhx9pzhj 4596 17 hemorrhage hemorrhage NN cord-005646-xhx9pzhj 4596 18 , , , cord-005646-xhx9pzhj 4596 19 two two CD cord-005646-xhx9pzhj 4596 20 from from IN cord-005646-xhx9pzhj 4596 21 sepsis sepsis NN cord-005646-xhx9pzhj 4596 22 or or CC cord-005646-xhx9pzhj 4596 23 mocardial mocardial JJ cord-005646-xhx9pzhj 4596 24 insufficiency insufficiency NN cord-005646-xhx9pzhj 4596 25 . . . cord-005646-xhx9pzhj 4597 1 Only only RB cord-005646-xhx9pzhj 4597 2 one one CD cord-005646-xhx9pzhj 4597 3 patient patient NN cord-005646-xhx9pzhj 4597 4 benefited benefit VBD cord-005646-xhx9pzhj 4597 5 from from IN cord-005646-xhx9pzhj 4597 6 catecholamine catecholamine NN cord-005646-xhx9pzhj 4597 7 support support NN cord-005646-xhx9pzhj 4597 8 which which WDT cord-005646-xhx9pzhj 4597 9 can can MD cord-005646-xhx9pzhj 4597 10 increase increase VB cord-005646-xhx9pzhj 4597 11 systemic systemic JJ cord-005646-xhx9pzhj 4597 12 resistance resistance NN cord-005646-xhx9pzhj 4597 13 unfaborably unfaborably RB cord-005646-xhx9pzhj 4597 14 . . . cord-005646-xhx9pzhj 4598 1 In in IN cord-005646-xhx9pzhj 4598 2 this this DT cord-005646-xhx9pzhj 4598 3 experience experience NN cord-005646-xhx9pzhj 4598 4 CO2 CO2 NNP cord-005646-xhx9pzhj 4598 5 was be VBD cord-005646-xhx9pzhj 4598 6 felt feel VBN cord-005646-xhx9pzhj 4598 7 to to TO cord-005646-xhx9pzhj 4598 8 be be VB cord-005646-xhx9pzhj 4598 9 an an DT cord-005646-xhx9pzhj 4598 10 important important JJ cord-005646-xhx9pzhj 4598 11 adjunct adjunct NN cord-005646-xhx9pzhj 4598 12 in in IN cord-005646-xhx9pzhj 4598 13 some some DT cord-005646-xhx9pzhj 4598 14 patients patient NNS cord-005646-xhx9pzhj 4598 15 pre pre VB cord-005646-xhx9pzhj 4598 16 - - JJ cord-005646-xhx9pzhj 4598 17 operatively operatively RB cord-005646-xhx9pzhj 4598 18 and and CC cord-005646-xhx9pzhj 4598 19 most most JJS cord-005646-xhx9pzhj 4598 20 patients patient NNS cord-005646-xhx9pzhj 4598 21 postoperatively postoperatively RB cord-005646-xhx9pzhj 4598 22 to to TO cord-005646-xhx9pzhj 4598 23 faborably faborably RB cord-005646-xhx9pzhj 4598 24 modulate modulate VB cord-005646-xhx9pzhj 4598 25 the the DT cord-005646-xhx9pzhj 4598 26 critically critically RB cord-005646-xhx9pzhj 4598 27 important important JJ cord-005646-xhx9pzhj 4598 28 systemic systemic JJ cord-005646-xhx9pzhj 4598 29 - - HYPH cord-005646-xhx9pzhj 4598 30 topulmonary topulmonary JJ cord-005646-xhx9pzhj 4598 31 flow flow NN cord-005646-xhx9pzhj 4598 32 ratio ratio NN cord-005646-xhx9pzhj 4598 33 , , , cord-005646-xhx9pzhj 4598 34 to to TO cord-005646-xhx9pzhj 4598 35 maximize maximize VB cord-005646-xhx9pzhj 4598 36 oxygen oxygen NN cord-005646-xhx9pzhj 4598 37 delivery delivery NN cord-005646-xhx9pzhj 4598 38 and and CC cord-005646-xhx9pzhj 4598 39 systemic systemic JJ cord-005646-xhx9pzhj 4598 40 perfusion perfusion NN cord-005646-xhx9pzhj 4598 41 , , , cord-005646-xhx9pzhj 4598 42 while while IN cord-005646-xhx9pzhj 4598 43 minimizing minimize VBG cord-005646-xhx9pzhj 4598 44 excessive excessive JJ cord-005646-xhx9pzhj 4598 45 right right JJ cord-005646-xhx9pzhj 4598 46 vantricular vantricular JJ cord-005646-xhx9pzhj 4598 47 volume volume NN cord-005646-xhx9pzhj 4598 48 work work NN cord-005646-xhx9pzhj 4598 49 . . .