id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-009385-mcfnhscj	BLECHA, FRANK	Rationale for Using Immunopotentiators in Domestic Food Animals	2012-11-05		.txt	text/plain	3483	217	39	Therefore, although fully immunocompetent at birth, domestic food animal newborns differ from other mammalian neonates in being im munologically "virgin" (Kim, 1975; Salmon, 1984) and the development of totally effective immune defenses requires 2 to 3 weeks. Because of the high incidence and economic impact of respiratory and intestinal infections in young domestic animals, it is important to review studies related to the postnatal development of the mucosaassociated immune system in the pig. Several examples of virus-related im munosuppression are well documented in domestic food animals (Table III) , including viral diseases of great economic importance such as infectious bovine rhinotracheitis (bovine herpesvirus type-1) and pseudorabies, which cause severe pneumonia and death in cattle and pigs, respectively. If immunomodulators can be used to augment immune function at critical periods during the production of food animals, such as the neonatal period, and prior to or during exposure to stressors or patho genic organisms, then the economic loss caused by infectious disease should be reduced.	./cache/cord-009385-mcfnhscj.txt	./txt/cord-009385-mcfnhscj.txt