id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-010921-yzv43e8l	Kaye, Alan David	Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain	2020-04-02		.txt	text/plain	7253	431	44	As such, dexmedetomidine is now being used as part of ERAS protocols along with regional nerve blocks and other medications, to create a satisfactory postoperative outcome with reduced opioid consumption in the Post anesthesia care unit (PACU). This manuscript will comprehensively discuss dexmedetomidine with regards to postoperative pain management, ERAS protocols, pharmacokinetics, pharmacodynamics, cardiovascular and respiratory effects, toxicity, drug interactions, abuse and dependence. Analgesia with non-opioids analgesics like dexmedetomidine are being used as part of an ERAS protocol intraoperatively, along with regional nerve blocks to attain a satisfactory postoperative outcome with reduced requirements of opioids in PACU in the pediatric population. In a 2015 meta-analysis, although dexmedetomidine reduced pain intensity, opioid consumption, and postoperative nausea and vomiting (PONV), it had no effect on recovery time [29] . Postoperative pain control after the use of dexmedetomidine and propofol to sedate patients undergoing ankle surgery under spinal anesthesia: a randomized controlled trial	./cache/cord-010921-yzv43e8l.txt	./txt/cord-010921-yzv43e8l.txt