id author title date pages extension mime words sentences flesch summary cache txt cord-013138-4e9vo0xr Lang-Illievich, Kordula The Effect of Low-Level Light Therapy on Capsaicin-Induced Peripheral and Central Sensitization in Healthy Volunteers: A Double-Blinded, Randomized, Sham-Controlled Trial 2020-10-10 .txt text/plain 3990 240 46 title: The Effect of Low-Level Light Therapy on Capsaicin-Induced Peripheral and Central Sensitization in Healthy Volunteers: A Double-Blinded, Randomized, Sham-Controlled Trial INTRODUCTION: Several clinical trials have demonstrated that low-level light therapy (LLLT), a method of photobiomodulation, is an effective analgetic treatment. This study aimed to evaluate the effect of low-level light therapy on primary and secondary hyperalgesia in a human pain model. CONCLUSIONS: Our data indicate that low-level light therapy is effective at reducing the heat and mechanical pain threshold in a human pain model, pointing to a significant modulating effect on peripheral and central sensitization. To provide an answer to these questions, we use a human pain model developed to mimic different aspects of clinical pain and to study pain mechanisms in order to examine whether peripheral or central mechanisms contribute to the analgetic effect of LLLT. ./cache/cord-013138-4e9vo0xr.txt ./txt/cord-013138-4e9vo0xr.txt