id author title date pages extension mime words sentences flesch summary cache txt cord-017504-rtg7fs82 Lim, T. K. Punica granatum 2012-11-03 .txt text/plain 31236 1613 46 The results suggested that the aril juice the major and tasty part of pomegranate fruit, did not contain ellagic acid and punicalagin (i.e. the polyphenols highly represented in the rind which appeared to be responsible for the antioxidant capacity) in amounts suf fi cient to exert cytoprotection in oxidatively injured, living cells. After consumption of pomegranate juice, fruit peel, aril and fl ower extracts the atherosclerotic lesion area in atherosclerotic apolipoprotein e-de fi cient (E 0) mice was signi fi cantly decreased by 44, 38, 39, 6, or 70%, respectively, as compared to placebo-treated group, while pomegranate seed oil had no effect. Further in-vitro studies showed that Punica granatum fl ower extract and its components oleanolic acid, ursolic acid, and gallic acid inhibited lipopolysaccharide-induced NF-kappaB activation in macrophages. In-vitro studies using normal human epidermal keratinocytes, showed that pre-treatment with pomegranate fruit extract rich in anthocyannins and hydrolyzable tannins protected against the adverse effects of UV-B radiation by inhibiting UV-B-induced modulations of nuclear factor kappa B (NF-kappaB) and mitogen-activated protein kinases (MAPK) pathways (Afaq et al. ./cache/cord-017504-rtg7fs82.txt ./txt/cord-017504-rtg7fs82.txt