id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-256881-7sejcqda	Heindel, Jerrold J.	Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies	2020-07-16		.txt	text/plain	24781	1195	47	Additionally, we applied an integrative analysis approach by using rand Circos-plots generated with the mixOmics [21] program to identify correlations in BPA responses across organs collected from the same or comparable individual rats within this same consortium study, thus expanding our findings to a systems biology level to reveal strong organismal relationships at three different timepoints: 21 days of age (weaning), 90-120 days of age (young adult) and 6 months of age (older adult). Fenton (National Toxicology Program) (mostly using rat models); (2) DNA methylation profiles and concomitant alterations of gene expression at PND 21 are predictors of pathological outcomes that manifest during adulthood, which was done in collaboration with Dr. Shioda, Mass General Hospital); (3) perinatal exposure to BPA induces abnormal post-pubertal/adult development of the mammary gland; and (4) BPA generates non-monotonic dose-response curves.	./cache/cord-256881-7sejcqda.txt	./txt/cord-256881-7sejcqda.txt