id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-256992-rwy0n01l	Taheri, Yasaman	Myricetin bioactive effects: moving from preclinical evidence to potential clinical applications	2020-08-01		.txt	text/plain	7256	458	40	Polyphenols are a wide group of plant-derived molecules resulting from secondary metabolism, ubiquitously distributed in vegetable kingdom where they display different activities such as protective effect against UV rays, bacteria, virus and fungi infections, modulation of plant hormones, enzyme inhibition and pollinator attraction [1] . [101] reported the in vitro effect of myricetin on high glucose-induced β-cell apoptosis, possibly via cyclin-dependent kinase 5 (CDK5) inhibition. Anti-angiogenic effects of myricetin (5 to 20 μM) assessed through in vitro (HUVEC) and in vivo (CAM) models revealed that this compound significantly inhibits angiogenesis induced by OVCAR-3 cells. In SKOV3 human ovarian cancer cells, myricetin inhibited viability and induced apoptosis (40 μg/mL, time-dependent manner) through endoplasmic reticulum stress and DNA double-strand breaks [130] . Potential anticancer activity of myricetin in human T24 bladder cancer cells both in vitro and in vivo	./cache/cord-256992-rwy0n01l.txt	./txt/cord-256992-rwy0n01l.txt