id author title date pages extension mime words sentences flesch summary cache txt cord-257514-gw9xnb4x Yang, Mengling Hydrogen: A Novel Option in Human Disease Treatment 2020-09-05 .txt text/plain 10425 526 33 H(2) gas may regulate the anti-inflammatory and antioxidant activity, mitochondrial energy metabolism, endoplasmic reticulum stress, the immune system, and cell death (apoptosis, autophagy, pyroptosis, ferroptosis, and circadian clock, among others) and has therapeutic potential for many systemic diseases. found that HW inhibited cardiomyocyte apoptosis by activating the PI3K/AKT and JAK2-STAT3 signaling pathways and can also reduce the level of oxidative stress in myocardial tissue by upregulating the expression of the nuclear erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) signaling pathway, which alleviated I/R injury in isolated rat hearts [39, 40, 91] . Effects of hydrogen-rich water on the PI3K/AKT signaling pathway in rats with myocardial 12 Oxidative Medicine and Cellular Longevity ischemia-reperfusion injury Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation ./cache/cord-257514-gw9xnb4x.txt ./txt/cord-257514-gw9xnb4x.txt