id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327521-g5vefajw	Spisni, Enzo	Antioxidant, Anti-Inflammatory, and Microbial-Modulating Activities of Essential Oils: Implications in Colonic Pathophysiology	2020-06-10		.txt	text/plain	9179	411	34	In recent years, many studies have analyzed their antimicrobial, antioxidant, anti-inflammatory, immunomodulatory and anticancer properties in vitro and on experimentally induced animal models of colitis and colorectal cancer. The recent discovery of the complexity of the human intestinal microbiota, composed of bacteria, fungi and viruses, and its intricate pathophysiological relationships with the immune system and the enteric nervous system, makes EOs truly interesting for their antimicrobial activities, often selective for the different microbial components. Recent studies have shown that geraniol administration reduced the intestinal inflammation induced by DSS [7] , but these anti-inflammatory effects could be also linked to its antioxidant activity, since its administration resulted in a decreased iNOS activity and a decreased lipid peroxidation, in a rat model of colitis [22] . Geraniol antibacterial activity seems to be linked to his property to destabilize bacterial cell wall and damage transmembrane efflux pumps, thus restoring drug-sensitivity in different bacterial antibiotic-resistant strains, such as Enterobacter aerogenes, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii [29] .	./cache/cord-327521-g5vefajw.txt	./txt/cord-327521-g5vefajw.txt