id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-344988-09vpehvf	Overbeck, Silke	Modulating the immune response by oral zinc supplementation: a single approach for multiple diseases	2008-02-05		.txt	text/plain	7943	395	41	Zinc supplementation in diseases such as diarrhea, chronic hepatitis C, shigellosis, leprosy, tuberculosis, pneumonia, acute lower respiratory infection, and leishmaniasis seems beneficial. Infection with the human immunodeficiency virus (HIV) results in the acquired immune deficiency syndrome (AIDS), a disease where zinc application was tested as a supporting therapeutic intervention [23] . [95] , there was no alteration of the CD4/CD8 ratio in the initial study [176] and several recent papers were unable to find effects of oral zinc on HIV-1 viral load, immune response to tuberculosis, lymphocyte subsets, CD4 + , CD8 + , and CD3 + cell counts, or antibody response to a pneumococcal conjugate vaccine [16, 27, 40, 54, 163] . Although this has not been directly investigated so far, the improvement in parameters for oxidative stress in diabetic patients indicates that the antioxidant effect of zinc is relevant for disease progression in vivo.	./cache/cord-344988-09vpehvf.txt	./txt/cord-344988-09vpehvf.txt