id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-347644-4qenzjiu	Shorter, John R.	A Diallel of the Mouse Collaborative Cross Founders Reveals Strong Strain-Specific Maternal Effects on Litter Size	2019-03-15		.txt	text/plain	6968	318	47	We identified factors that affect the average litter size in a cross by estimating the overall contribution of parent-of-origin, heterosis, inbred, and epistatic effects using a Bayesian zero-truncated overdispersed Poisson mixed model. Litter size is moderately heritable, and maternal effects account for the majority of explained variation To estimate founder strain effects on litter size, we used a Bayesian regression model that decomposes the phenotypic variation in the diallel into genetic and parent-of-origin contributions (Lenarcic et al. Using this model, the percentage of the variance in litter size explained by diallel effects was 17.73%, with additive effects explaining 9.18% (VarP[additive]; this GCA-like measure being related to narrow sense heritability), parent-of-origin effects (VarP[parental.sex]) accounting for 5.77%, the fact of being inbred (VarP[inbred.overall]) at 1.43%, and strain-by-strain interactions (VarP[epistatic.symmetric] + VarP[asymmetric.epistatic]) at 3.40% (Figure 2A) .	./cache/cord-347644-4qenzjiu.txt	./txt/cord-347644-4qenzjiu.txt