id	sid	tid	token	lemma	pos
cord-257197-i9bucuma	1	1	key	key	JJ
cord-257197-i9bucuma	2	1	:	:	:
cord-257197-i9bucuma	2	2	cord-257197-i9bucuma	cord-257197-i9bucuma	NN
cord-257197-i9bucuma	2	3	authors	author	NNS
cord-257197-i9bucuma	2	4	:	:	:
cord-257197-i9bucuma	3	1	Natarajan	Natarajan	NNP
cord-257197-i9bucuma	3	2	,	,	,
cord-257197-i9bucuma	3	3	Pavithra	Pavithra	NNP
cord-257197-i9bucuma	3	4	;	;	:
cord-257197-i9bucuma	3	5	Tomich	Tomich	NNP
cord-257197-i9bucuma	3	6	,	,	,
cord-257197-i9bucuma	3	7	John	John	NNP
cord-257197-i9bucuma	3	8	M.	M.	NNP
cord-257197-i9bucuma	3	9	title	title	NN
cord-257197-i9bucuma	3	10	:	:	:
cord-257197-i9bucuma	3	11	Understanding	understand	VBG
cord-257197-i9bucuma	3	12	the	the	DT
cord-257197-i9bucuma	3	13	influence	influence	NN
cord-257197-i9bucuma	3	14	of	of	IN
cord-257197-i9bucuma	3	15	experimental	experimental	JJ
cord-257197-i9bucuma	3	16	factors	factor	NNS
cord-257197-i9bucuma	3	17	on	on	IN
cord-257197-i9bucuma	3	18	bio	bio	NN
cord-257197-i9bucuma	3	19	-	-	NNS
cord-257197-i9bucuma	3	20	interactions	interaction	NNS
cord-257197-i9bucuma	3	21	of	of	IN
cord-257197-i9bucuma	3	22	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	3	23	:	:	:
cord-257197-i9bucuma	4	1	Towards	towards	IN
cord-257197-i9bucuma	4	2	improving	improve	VBG
cord-257197-i9bucuma	4	3	correlation	correlation	NN
cord-257197-i9bucuma	4	4	between	between	IN
cord-257197-i9bucuma	4	5	in	in	IN
cord-257197-i9bucuma	4	6	vitro	vitro	FW
cord-257197-i9bucuma	4	7	and	and	CC
cord-257197-i9bucuma	4	8	in	in	IN
cord-257197-i9bucuma	4	9	vivo	vivo	NNP
cord-257197-i9bucuma	4	10	studies	study	NNS
cord-257197-i9bucuma	4	11	date	date	NN
cord-257197-i9bucuma	4	12	:	:	:
cord-257197-i9bucuma	4	13	2020	2020	CD
cord-257197-i9bucuma	4	14	-	-	HYPH
cord-257197-i9bucuma	4	15	09	09	CD
cord-257197-i9bucuma	4	16	-	-	SYM
cord-257197-i9bucuma	4	17	21	21	CD
cord-257197-i9bucuma	4	18	journal	journal	NN
cord-257197-i9bucuma	4	19	:	:	:
cord-257197-i9bucuma	5	1	Arch	Arch	NNP
cord-257197-i9bucuma	5	2	Biochem	Biochem	NNP
cord-257197-i9bucuma	6	1	Biophys	Biophys	NNP
cord-257197-i9bucuma	6	2	DOI	DOI	NNP
cord-257197-i9bucuma	6	3	:	:	:
cord-257197-i9bucuma	6	4	10.1016	10.1016	CD
cord-257197-i9bucuma	6	5	/	/	SYM
cord-257197-i9bucuma	6	6	j.abb.2020.108592	j.abb.2020.108592	NNP
cord-257197-i9bucuma	6	7	sha	sha	NN
cord-257197-i9bucuma	6	8	:	:	:
cord-257197-i9bucuma	6	9	d001d53a3afe527d2b2bb7bcc078679e54e90cd9	d001d53a3afe527d2b2bb7bcc078679e54e90cd9	NNP
cord-257197-i9bucuma	6	10	doc_id	doc_id	CD
cord-257197-i9bucuma	6	11	:	:	:
cord-257197-i9bucuma	6	12	257197	257197	CD
cord-257197-i9bucuma	6	13	cord_uid	cord_uid	NNS
cord-257197-i9bucuma	6	14	:	:	:
cord-257197-i9bucuma	7	1	i9bucuma	i9bucuma	NNP
cord-257197-i9bucuma	7	2	Bionanotechnology	Bionanotechnology	NNP
cord-257197-i9bucuma	7	3	has	have	VBZ
cord-257197-i9bucuma	7	4	developed	develop	VBN
cord-257197-i9bucuma	7	5	rapidly	rapidly	RB
cord-257197-i9bucuma	7	6	over	over	IN
cord-257197-i9bucuma	7	7	the	the	DT
cord-257197-i9bucuma	7	8	past	past	JJ
cord-257197-i9bucuma	7	9	two	two	CD
cord-257197-i9bucuma	7	10	decades	decade	NNS
cord-257197-i9bucuma	7	11	,	,	,
cord-257197-i9bucuma	7	12	owing	owe	VBG
cord-257197-i9bucuma	7	13	to	to	IN
cord-257197-i9bucuma	7	14	the	the	DT
cord-257197-i9bucuma	7	15	extensive	extensive	JJ
cord-257197-i9bucuma	7	16	and	and	CC
cord-257197-i9bucuma	7	17	versatile	versatile	JJ
cord-257197-i9bucuma	7	18	,	,	,
cord-257197-i9bucuma	7	19	functionalities	functionality	NNS
cord-257197-i9bucuma	7	20	and	and	CC
cord-257197-i9bucuma	7	21	applicability	applicability	NN
cord-257197-i9bucuma	7	22	of	of	IN
cord-257197-i9bucuma	7	23	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	7	24	(	(	-LRB-
cord-257197-i9bucuma	7	25	NPs	NPs	NNP
cord-257197-i9bucuma	7	26	)	)	-RRB-
cord-257197-i9bucuma	7	27	.	.	.
cord-257197-i9bucuma	8	1	Fifty	fifty	CD
cord-257197-i9bucuma	8	2	-	-	HYPH
cord-257197-i9bucuma	8	3	one	one	CD
cord-257197-i9bucuma	8	4	nanomedicines	nanomedicine	NNS
cord-257197-i9bucuma	8	5	have	have	VBP
cord-257197-i9bucuma	8	6	been	be	VBN
cord-257197-i9bucuma	8	7	approved	approve	VBN
cord-257197-i9bucuma	8	8	by	by	IN
cord-257197-i9bucuma	8	9	FDA	FDA	NNP
cord-257197-i9bucuma	8	10	since	since	IN
cord-257197-i9bucuma	8	11	1995	1995	CD
cord-257197-i9bucuma	8	12	,	,	,
cord-257197-i9bucuma	8	13	out	out	IN
cord-257197-i9bucuma	8	14	of	of	IN
cord-257197-i9bucuma	8	15	the	the	DT
cord-257197-i9bucuma	8	16	many	many	JJ
cord-257197-i9bucuma	8	17	NPs	np	NNS
cord-257197-i9bucuma	8	18	based	base	VBN
cord-257197-i9bucuma	8	19	formulations	formulation	NNS
cord-257197-i9bucuma	8	20	developed	develop	VBD
cord-257197-i9bucuma	8	21	to	to	IN
cord-257197-i9bucuma	8	22	date	date	NN
cord-257197-i9bucuma	8	23	.	.	.
cord-257197-i9bucuma	9	1	The	the	DT
cord-257197-i9bucuma	9	2	general	general	JJ
cord-257197-i9bucuma	9	3	conformation	conformation	NN
cord-257197-i9bucuma	9	4	of	of	IN
cord-257197-i9bucuma	9	5	NPs	NPs	NNP
cord-257197-i9bucuma	9	6	consists	consist	VBZ
cord-257197-i9bucuma	9	7	of	of	IN
cord-257197-i9bucuma	9	8	a	a	DT
cord-257197-i9bucuma	9	9	core	core	NN
cord-257197-i9bucuma	9	10	with	with	IN
cord-257197-i9bucuma	9	11	ligands	ligand	NNS
cord-257197-i9bucuma	9	12	coating	coat	VBG
cord-257197-i9bucuma	9	13	their	-PRON-	PRP$
cord-257197-i9bucuma	9	14	surface	surface	NN
cord-257197-i9bucuma	9	15	,	,	,
cord-257197-i9bucuma	9	16	that	that	WDT
cord-257197-i9bucuma	9	17	stabilizes	stabilize	VBZ
cord-257197-i9bucuma	9	18	them	-PRON-	PRP
cord-257197-i9bucuma	9	19	and	and	CC
cord-257197-i9bucuma	9	20	provides	provide	VBZ
cord-257197-i9bucuma	9	21	them	-PRON-	PRP
cord-257197-i9bucuma	9	22	with	with	IN
cord-257197-i9bucuma	9	23	added	add	VBN
cord-257197-i9bucuma	9	24	functionalities	functionality	NNS
cord-257197-i9bucuma	9	25	.	.	.
cord-257197-i9bucuma	10	1	The	the	DT
cord-257197-i9bucuma	10	2	physicochemical	physicochemical	JJ
cord-257197-i9bucuma	10	3	properties	property	NNS
cord-257197-i9bucuma	10	4	,	,	,
cord-257197-i9bucuma	10	5	especially	especially	RB
cord-257197-i9bucuma	10	6	the	the	DT
cord-257197-i9bucuma	10	7	surface	surface	NN
cord-257197-i9bucuma	10	8	composition	composition	NN
cord-257197-i9bucuma	10	9	of	of	IN
cord-257197-i9bucuma	10	10	NPs	NPs	NNP
cord-257197-i9bucuma	10	11	influence	influence	VBP
cord-257197-i9bucuma	10	12	their	-PRON-	PRP$
cord-257197-i9bucuma	10	13	bio	bio	NN
cord-257197-i9bucuma	10	14	-	-	NNS
cord-257197-i9bucuma	10	15	interactions	interaction	NNS
cord-257197-i9bucuma	10	16	to	to	IN
cord-257197-i9bucuma	10	17	a	a	DT
cord-257197-i9bucuma	10	18	large	large	JJ
cord-257197-i9bucuma	10	19	extent	extent	NN
cord-257197-i9bucuma	10	20	.	.	.
cord-257197-i9bucuma	11	1	This	this	DT
cord-257197-i9bucuma	11	2	review	review	NN
cord-257197-i9bucuma	11	3	discusses	discuss	VBZ
cord-257197-i9bucuma	11	4	recent	recent	JJ
cord-257197-i9bucuma	11	5	studies	study	NNS
cord-257197-i9bucuma	11	6	that	that	WDT
cord-257197-i9bucuma	11	7	help	help	VBP
cord-257197-i9bucuma	11	8	understand	understand	VB
cord-257197-i9bucuma	11	9	the	the	DT
cord-257197-i9bucuma	11	10	nano	nano	NNP
cord-257197-i9bucuma	11	11	-	-	HYPH
cord-257197-i9bucuma	11	12	bio	bio	JJ
cord-257197-i9bucuma	11	13	interactions	interaction	NNS
cord-257197-i9bucuma	11	14	of	of	IN
cord-257197-i9bucuma	11	15	iron	iron	NN
cord-257197-i9bucuma	11	16	oxide	oxide	NN
cord-257197-i9bucuma	11	17	and	and	CC
cord-257197-i9bucuma	11	18	gold	gold	NN
cord-257197-i9bucuma	11	19	NPs	np	NNS
cord-257197-i9bucuma	11	20	with	with	IN
cord-257197-i9bucuma	11	21	different	different	JJ
cord-257197-i9bucuma	11	22	surface	surface	NN
cord-257197-i9bucuma	11	23	compositions	composition	NNS
cord-257197-i9bucuma	11	24	.	.	.
cord-257197-i9bucuma	12	1	We	-PRON-	PRP
cord-257197-i9bucuma	12	2	discuss	discuss	VBP
cord-257197-i9bucuma	12	3	the	the	DT
cord-257197-i9bucuma	12	4	influence	influence	NN
cord-257197-i9bucuma	12	5	of	of	IN
cord-257197-i9bucuma	12	6	the	the	DT
cord-257197-i9bucuma	12	7	experimental	experimental	JJ
cord-257197-i9bucuma	12	8	factors	factor	NNS
cord-257197-i9bucuma	12	9	on	on	IN
cord-257197-i9bucuma	12	10	the	the	DT
cord-257197-i9bucuma	12	11	outcome	outcome	NN
cord-257197-i9bucuma	12	12	of	of	IN
cord-257197-i9bucuma	12	13	the	the	DT
cord-257197-i9bucuma	12	14	studies	study	NNS
cord-257197-i9bucuma	12	15	and	and	CC
cord-257197-i9bucuma	12	16	,	,	,
cord-257197-i9bucuma	12	17	thus	thus	RB
cord-257197-i9bucuma	12	18	,	,	,
cord-257197-i9bucuma	12	19	the	the	DT
cord-257197-i9bucuma	12	20	importance	importance	NN
cord-257197-i9bucuma	12	21	of	of	IN
cord-257197-i9bucuma	12	22	standardization	standardization	NN
cord-257197-i9bucuma	12	23	in	in	IN
cord-257197-i9bucuma	12	24	the	the	DT
cord-257197-i9bucuma	12	25	field	field	NN
cord-257197-i9bucuma	12	26	of	of	IN
cord-257197-i9bucuma	12	27	nanotechnology	nanotechnology	NN
cord-257197-i9bucuma	12	28	.	.	.
cord-257197-i9bucuma	13	1	Recent	recent	JJ
cord-257197-i9bucuma	13	2	studies	study	NNS
cord-257197-i9bucuma	13	3	suggest	suggest	VBP
cord-257197-i9bucuma	13	4	that	that	IN
cord-257197-i9bucuma	13	5	with	with	IN
cord-257197-i9bucuma	13	6	careful	careful	JJ
cord-257197-i9bucuma	13	7	selection	selection	NN
cord-257197-i9bucuma	13	8	of	of	IN
cord-257197-i9bucuma	13	9	experimental	experimental	JJ
cord-257197-i9bucuma	13	10	parameters	parameter	NNS
cord-257197-i9bucuma	13	11	,	,	,
cord-257197-i9bucuma	13	12	it	-PRON-	PRP
cord-257197-i9bucuma	13	13	is	be	VBZ
cord-257197-i9bucuma	13	14	possible	possible	JJ
cord-257197-i9bucuma	13	15	to	to	TO
cord-257197-i9bucuma	13	16	improve	improve	VB
cord-257197-i9bucuma	13	17	the	the	DT
cord-257197-i9bucuma	13	18	positive	positive	JJ
cord-257197-i9bucuma	13	19	correlation	correlation	NN
cord-257197-i9bucuma	13	20	between	between	IN
cord-257197-i9bucuma	13	21	in	in	IN
cord-257197-i9bucuma	13	22	vitro	vitro	FW
cord-257197-i9bucuma	13	23	and	and	CC
cord-257197-i9bucuma	13	24	in	in	IN
cord-257197-i9bucuma	13	25	vivo	vivo	NNP
cord-257197-i9bucuma	13	26	studies	study	NNS
cord-257197-i9bucuma	13	27	.	.	.
cord-257197-i9bucuma	14	1	This	this	DT
cord-257197-i9bucuma	14	2	provides	provide	VBZ
cord-257197-i9bucuma	14	3	a	a	DT
cord-257197-i9bucuma	14	4	fundamental	fundamental	JJ
cord-257197-i9bucuma	14	5	understanding	understanding	NN
cord-257197-i9bucuma	14	6	of	of	IN
cord-257197-i9bucuma	14	7	the	the	DT
cord-257197-i9bucuma	14	8	NPs	NPs	NNPS
cord-257197-i9bucuma	14	9	which	which	WDT
cord-257197-i9bucuma	14	10	helps	help	VBZ
cord-257197-i9bucuma	14	11	in	in	IN
cord-257197-i9bucuma	14	12	assessing	assess	VBG
cord-257197-i9bucuma	14	13	their	-PRON-	PRP$
cord-257197-i9bucuma	14	14	potential	potential	JJ
cord-257197-i9bucuma	14	15	toxic	toxic	JJ
cord-257197-i9bucuma	14	16	side	side	NN
cord-257197-i9bucuma	14	17	effects	effect	NNS
cord-257197-i9bucuma	14	18	and	and	CC
cord-257197-i9bucuma	14	19	may	may	MD
cord-257197-i9bucuma	14	20	aid	aid	VB
cord-257197-i9bucuma	14	21	in	in	IN
cord-257197-i9bucuma	14	22	manipulating	manipulate	VBG
cord-257197-i9bucuma	14	23	them	-PRON-	PRP
cord-257197-i9bucuma	14	24	further	further	RB
cord-257197-i9bucuma	14	25	to	to	TO
cord-257197-i9bucuma	14	26	improve	improve	VB
cord-257197-i9bucuma	14	27	their	-PRON-	PRP$
cord-257197-i9bucuma	14	28	biocompatibility	biocompatibility	NN
cord-257197-i9bucuma	14	29	and	and	CC
cord-257197-i9bucuma	14	30	biosafety	biosafety	NN
cord-257197-i9bucuma	14	31	.	.	.
cord-257197-i9bucuma	15	1	The	the	DT
cord-257197-i9bucuma	15	2	term	term	NN
cord-257197-i9bucuma	15	3	nanotechnology	nanotechnology	NN
cord-257197-i9bucuma	15	4	was	be	VBD
cord-257197-i9bucuma	15	5	coined	coin	VBN
cord-257197-i9bucuma	15	6	by	by	IN
cord-257197-i9bucuma	15	7	Prof.	Prof.	NNP
cord-257197-i9bucuma	15	8	Norio	Norio	NNP
cord-257197-i9bucuma	15	9	Taniguchi	Taniguchi	NNP
cord-257197-i9bucuma	15	10	in	in	IN
cord-257197-i9bucuma	15	11	1974	1974	CD
cord-257197-i9bucuma	15	12	and	and	CC
cord-257197-i9bucuma	15	13	is	be	VBZ
cord-257197-i9bucuma	15	14	defined	define	VBN
cord-257197-i9bucuma	15	15	as	as	IN
cord-257197-i9bucuma	15	16	the	the	DT
cord-257197-i9bucuma	15	17	science	science	NN
cord-257197-i9bucuma	15	18	,	,	,
cord-257197-i9bucuma	15	19	engineering	engineering	NN
cord-257197-i9bucuma	15	20	and	and	CC
cord-257197-i9bucuma	15	21	technology	technology	NN
cord-257197-i9bucuma	15	22	conducted	conduct	VBN
cord-257197-i9bucuma	15	23	at	at	IN
cord-257197-i9bucuma	15	24	the	the	DT
cord-257197-i9bucuma	15	25	nanoscale	nanoscale	NN
cord-257197-i9bucuma	15	26	i.e.	i.e.	FW
cord-257197-i9bucuma	15	27	1	1	CD
cord-257197-i9bucuma	15	28	to	to	IN
cord-257197-i9bucuma	15	29	100	100	CD
cord-257197-i9bucuma	15	30	nm	nm	NN
cord-257197-i9bucuma	15	31	.	.	.
cord-257197-i9bucuma	16	1	The	the	DT
cord-257197-i9bucuma	16	2	nanoscale	nanoscale	JJ
cord-257197-i9bucuma	16	3	materials	material	NNS
cord-257197-i9bucuma	16	4	generally	generally	RB
cord-257197-i9bucuma	16	5	referred	refer	VBN
cord-257197-i9bucuma	16	6	to	to	IN
cord-257197-i9bucuma	16	7	as	as	IN
cord-257197-i9bucuma	16	8	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	16	9	(	(	-LRB-
cord-257197-i9bucuma	16	10	NPs	NPs	NNP
cord-257197-i9bucuma	16	11	)	)	-RRB-
cord-257197-i9bucuma	16	12	are	be	VBP
cord-257197-i9bucuma	16	13	highly	highly	RB
cord-257197-i9bucuma	16	14	desirable	desirable	JJ
cord-257197-i9bucuma	16	15	because	because	IN
cord-257197-i9bucuma	16	16	of	of	IN
cord-257197-i9bucuma	16	17	their	-PRON-	PRP$
cord-257197-i9bucuma	16	18	small	small	JJ
cord-257197-i9bucuma	16	19	size	size	NN
cord-257197-i9bucuma	16	20	,	,	,
cord-257197-i9bucuma	16	21	optical	optical	JJ
cord-257197-i9bucuma	16	22	properties	property	NNS
cord-257197-i9bucuma	16	23	,	,	,
cord-257197-i9bucuma	16	24	high	high	JJ
cord-257197-i9bucuma	16	25	surface	surface	NN
cord-257197-i9bucuma	16	26	area	area	NN
cord-257197-i9bucuma	16	27	to	to	TO
cord-257197-i9bucuma	16	28	volume	volume	NN
cord-257197-i9bucuma	16	29	ratio	ratio	NN
cord-257197-i9bucuma	16	30	and	and	CC
cord-257197-i9bucuma	16	31	their	-PRON-	PRP$
cord-257197-i9bucuma	16	32	multifunctional	multifunctional	JJ
cord-257197-i9bucuma	16	33	nature	nature	NN
cord-257197-i9bucuma	16	34	.	.	.
cord-257197-i9bucuma	17	1	Bionanotechnology	bionanotechnology	NN
cord-257197-i9bucuma	17	2	comprises	comprise	VBZ
cord-257197-i9bucuma	17	3	research	research	NN
cord-257197-i9bucuma	17	4	at	at	IN
cord-257197-i9bucuma	17	5	the	the	DT
cord-257197-i9bucuma	17	6	interface	interface	NN
cord-257197-i9bucuma	17	7	of	of	IN
cord-257197-i9bucuma	17	8	nanotechnology	nanotechnology	NN
cord-257197-i9bucuma	17	9	and	and	CC
cord-257197-i9bucuma	17	10	biology	biology	NN
cord-257197-i9bucuma	17	11	2	2	CD
cord-257197-i9bucuma	17	12	that	that	WDT
cord-257197-i9bucuma	17	13	has	have	VBZ
cord-257197-i9bucuma	17	14	established	establish	VBN
cord-257197-i9bucuma	17	15	a	a	DT
cord-257197-i9bucuma	17	16	niche	niche	NN
cord-257197-i9bucuma	17	17	in	in	IN
cord-257197-i9bucuma	17	18	biomedical	biomedical	JJ
cord-257197-i9bucuma	17	19	sciences	science	NNS
cord-257197-i9bucuma	17	20	.	.	.
cord-257197-i9bucuma	18	1	Liposomes	liposome	NNS
cord-257197-i9bucuma	18	2	3	3	CD
cord-257197-i9bucuma	18	3	-	-	SYM
cord-257197-i9bucuma	18	4	6	6	CD
cord-257197-i9bucuma	18	5	,	,	,
cord-257197-i9bucuma	18	6	peptide	peptide	NN
cord-257197-i9bucuma	18	7	-	-	HYPH
cord-257197-i9bucuma	18	8	based	base	VBN
cord-257197-i9bucuma	18	9	[	[	-LRB-
cord-257197-i9bucuma	18	10	7	7	CD
cord-257197-i9bucuma	18	11	]	]	-RRB-
cord-257197-i9bucuma	18	12	[	[	-LRB-
cord-257197-i9bucuma	18	13	8	8	CD
cord-257197-i9bucuma	18	14	]	]	-RRB-
cord-257197-i9bucuma	18	15	[	[	-LRB-
cord-257197-i9bucuma	18	16	9	9	CD
cord-257197-i9bucuma	18	17	]	]	-RRB-
cord-257197-i9bucuma	18	18	and	and	CC
cord-257197-i9bucuma	18	19	synthetic	synthetic	JJ
cord-257197-i9bucuma	18	20	polymer	polymer	NN
cord-257197-i9bucuma	18	21	-	-	HYPH
cord-257197-i9bucuma	18	22	based	base	VBN
cord-257197-i9bucuma	18	23	[	[	-LRB-
cord-257197-i9bucuma	18	24	10	10	CD
cord-257197-i9bucuma	18	25	]	]	-RRB-
cord-257197-i9bucuma	18	26	[	[	-LRB-
cord-257197-i9bucuma	18	27	11	11	CD
cord-257197-i9bucuma	18	28	]	]	-RRB-
cord-257197-i9bucuma	18	29	[	[	-LRB-
cord-257197-i9bucuma	18	30	12	12	CD
cord-257197-i9bucuma	18	31	]	]	-RRB-
cord-257197-i9bucuma	18	32	,	,	,
cord-257197-i9bucuma	18	33	three	three	CD
cord-257197-i9bucuma	18	34	-	-	HYPH
cord-257197-i9bucuma	18	35	dimensional	dimensional	JJ
cord-257197-i9bucuma	18	36	macromolecular	macromolecular	JJ
cord-257197-i9bucuma	18	37	assemblies	assembly	NNS
cord-257197-i9bucuma	18	38	and	and	CC
cord-257197-i9bucuma	18	39	nanocages	nanocages	NNP
cord-257197-i9bucuma	18	40	[	[	-LRB-
cord-257197-i9bucuma	18	41	13	13	CD
cord-257197-i9bucuma	18	42	]	]	-RRB-
cord-257197-i9bucuma	18	43	[	[	-LRB-
cord-257197-i9bucuma	18	44	14	14	CD
cord-257197-i9bucuma	18	45	]	]	-RRB-
cord-257197-i9bucuma	18	46	[	[	-LRB-
cord-257197-i9bucuma	18	47	15	15	CD
cord-257197-i9bucuma	18	48	]	]	-RRB-
cord-257197-i9bucuma	18	49	are	be	VBP
cord-257197-i9bucuma	18	50	examples	example	NNS
cord-257197-i9bucuma	18	51	of	of	IN
cord-257197-i9bucuma	18	52	hollow	hollow	JJ
cord-257197-i9bucuma	18	53	/	/	SYM
cord-257197-i9bucuma	18	54	porous	porous	JJ
cord-257197-i9bucuma	18	55	core	core	NN
cord-257197-i9bucuma	18	56	NPs	NPs	NNP
cord-257197-i9bucuma	18	57	.	.	.
cord-257197-i9bucuma	19	1	Solid	solid	JJ
cord-257197-i9bucuma	19	2	core	core	NN
cord-257197-i9bucuma	19	3	NPs	NPs	NNP
cord-257197-i9bucuma	19	4	may	may	MD
cord-257197-i9bucuma	19	5	be	be	VB
cord-257197-i9bucuma	19	6	composed	compose	VBN
cord-257197-i9bucuma	19	7	of	of	IN
cord-257197-i9bucuma	19	8	inorganic	inorganic	JJ
cord-257197-i9bucuma	19	9	metals	metal	NNS
cord-257197-i9bucuma	19	10	such	such	JJ
cord-257197-i9bucuma	19	11	as	as	IN
cord-257197-i9bucuma	19	12	iron	iron	NN
cord-257197-i9bucuma	19	13	oxide	oxide	NN
cord-257197-i9bucuma	19	14	,	,	,
cord-257197-i9bucuma	19	15	gold	gold	NN
cord-257197-i9bucuma	19	16	,	,	,
cord-257197-i9bucuma	19	17	silver	silver	NN
cord-257197-i9bucuma	19	18	,	,	,
cord-257197-i9bucuma	19	19	platinum	platinum	NN
cord-257197-i9bucuma	19	20	,	,	,
cord-257197-i9bucuma	19	21	silicon	silicon	NN
cord-257197-i9bucuma	19	22	,	,	,
cord-257197-i9bucuma	19	23	quantum	quantum	NN
cord-257197-i9bucuma	19	24	dots	dot	NNS
cord-257197-i9bucuma	19	25	,	,	,
cord-257197-i9bucuma	19	26	titanium	titanium	NN
cord-257197-i9bucuma	19	27	dioxide	dioxide	NN
cord-257197-i9bucuma	19	28	,	,	,
cord-257197-i9bucuma	19	29	gadolinium	gadolinium	NN
cord-257197-i9bucuma	19	30	,	,	,
cord-257197-i9bucuma	19	31	selenium	selenium	NN
cord-257197-i9bucuma	19	32	,	,	,
cord-257197-i9bucuma	19	33	copper	copper	NN
cord-257197-i9bucuma	19	34	oxide	oxide	NN
cord-257197-i9bucuma	19	35	,	,	,
cord-257197-i9bucuma	19	36	zinc	zinc	NN
cord-257197-i9bucuma	19	37	oxide	oxide	NN
cord-257197-i9bucuma	19	38	or	or	CC
cord-257197-i9bucuma	19	39	metallic	metallic	JJ
cord-257197-i9bucuma	19	40	hybrids	hybrid	NNS
cord-257197-i9bucuma	19	41	,	,	,
cord-257197-i9bucuma	19	42	or	or	CC
cord-257197-i9bucuma	19	43	organic	organic	JJ
cord-257197-i9bucuma	19	44	carbon	carbon	NN
cord-257197-i9bucuma	19	45	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	19	46	.	.	.
cord-257197-i9bucuma	20	1	The	the	DT
cord-257197-i9bucuma	20	2	surfaces	surface	NNS
cord-257197-i9bucuma	20	3	of	of	IN
cord-257197-i9bucuma	20	4	inorganic	inorganic	JJ
cord-257197-i9bucuma	20	5	NPs	NPs	NNPS
cord-257197-i9bucuma	20	6	are	be	VBP
cord-257197-i9bucuma	20	7	generally	generally	RB
cord-257197-i9bucuma	20	8	modified	modify	VBN
cord-257197-i9bucuma	20	9	with	with	IN
cord-257197-i9bucuma	20	10	synthetic	synthetic	JJ
cord-257197-i9bucuma	20	11	or	or	CC
cord-257197-i9bucuma	20	12	naturally	naturally	RB
cord-257197-i9bucuma	20	13	occurring	occur	VBG
cord-257197-i9bucuma	20	14	polymers	polymer	NNS
cord-257197-i9bucuma	20	15	and/or	and/or	CC
cord-257197-i9bucuma	20	16	monomers	monomer	NNS
cord-257197-i9bucuma	20	17	which	which	WDT
cord-257197-i9bucuma	20	18	may	may	MD
cord-257197-i9bucuma	20	19	be	be	VB
cord-257197-i9bucuma	20	20	of	of	IN
cord-257197-i9bucuma	20	21	biological	biological	JJ
cord-257197-i9bucuma	20	22	origin	origin	NN
cord-257197-i9bucuma	20	23	such	such	JJ
cord-257197-i9bucuma	20	24	as	as	IN
cord-257197-i9bucuma	20	25	peptides	peptide	NNS
cord-257197-i9bucuma	20	26	,	,	,
cord-257197-i9bucuma	20	27	proteins	protein	NNS
cord-257197-i9bucuma	20	28	,	,	,
cord-257197-i9bucuma	20	29	carbohydrates	carbohydrate	NNS
cord-257197-i9bucuma	20	30	,	,	,
cord-257197-i9bucuma	20	31	lipids	lipid	NNS
cord-257197-i9bucuma	20	32	,	,	,
cord-257197-i9bucuma	20	33	DNA	DNA	NNP
cord-257197-i9bucuma	20	34	,	,	,
cord-257197-i9bucuma	20	35	RNA	RNA	NNP
cord-257197-i9bucuma	20	36	,	,	,
cord-257197-i9bucuma	20	37	PNA	PNA	NNP
cord-257197-i9bucuma	20	38	,	,	,
cord-257197-i9bucuma	20	39	aptamers	aptamer	NNS
cord-257197-i9bucuma	20	40	,	,	,
cord-257197-i9bucuma	20	41	hybrid	hybrid	JJ
cord-257197-i9bucuma	20	42	bio	bio	JJ
cord-257197-i9bucuma	20	43	-	-	HYPH
cord-257197-i9bucuma	20	44	synthetic	synthetic	JJ
cord-257197-i9bucuma	20	45	molecules	molecule	NNS
cord-257197-i9bucuma	20	46	and	and	CC
cord-257197-i9bucuma	20	47	others	other	NNS
cord-257197-i9bucuma	20	48	.	.	.
cord-257197-i9bucuma	21	1	These	these	DT
cord-257197-i9bucuma	21	2	relatively	relatively	RB
cord-257197-i9bucuma	21	3	flexible	flexible	JJ
cord-257197-i9bucuma	21	4	capping	capping	NN
cord-257197-i9bucuma	21	5	ligands	ligand	NNS
cord-257197-i9bucuma	21	6	improve	improve	VBP
cord-257197-i9bucuma	21	7	the	the	DT
cord-257197-i9bucuma	21	8	stability	stability	NN
cord-257197-i9bucuma	21	9	,	,	,
cord-257197-i9bucuma	21	10	biocompatibility	biocompatibility	NN
cord-257197-i9bucuma	21	11	and	and	CC
cord-257197-i9bucuma	21	12	functionalize	functionalize	NNP
cord-257197-i9bucuma	21	13	the	the	DT
cord-257197-i9bucuma	21	14	NPs	NPs	NNPS
cord-257197-i9bucuma	21	15	for	for	IN
cord-257197-i9bucuma	21	16	various	various	JJ
cord-257197-i9bucuma	21	17	applications	application	NNS
cord-257197-i9bucuma	21	18	or	or	CC
cord-257197-i9bucuma	21	19	for	for	IN
cord-257197-i9bucuma	21	20	further	further	JJ
cord-257197-i9bucuma	21	21	modifications	modification	NNS
cord-257197-i9bucuma	21	22	.	.	.
cord-257197-i9bucuma	22	1	Fig	Fig	NNP
cord-257197-i9bucuma	22	2	.	.	NNP
cord-257197-i9bucuma	22	3	1	1	CD
cord-257197-i9bucuma	22	4	,	,	,
cord-257197-i9bucuma	22	5	depicts	depict	VBZ
cord-257197-i9bucuma	22	6	the	the	DT
cord-257197-i9bucuma	22	7	various	various	JJ
cord-257197-i9bucuma	22	8	components	component	NNS
cord-257197-i9bucuma	22	9	and	and	CC
cord-257197-i9bucuma	22	10	configurations	configuration	NNS
cord-257197-i9bucuma	22	11	of	of	IN
cord-257197-i9bucuma	22	12	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	22	13	-	-	HYPH
cord-257197-i9bucuma	22	14	bioconjugates	bioconjugate	NNS
cord-257197-i9bucuma	22	15	.	.	.
cord-257197-i9bucuma	23	1	Drugs	drug	NNS
cord-257197-i9bucuma	23	2	that	that	WDT
cord-257197-i9bucuma	23	3	have	have	VBP
cord-257197-i9bucuma	23	4	poor	poor	JJ
cord-257197-i9bucuma	23	5	pharmacodynamics	pharmacodynamic	NNS
cord-257197-i9bucuma	23	6	can	can	MD
cord-257197-i9bucuma	23	7	be	be	VB
cord-257197-i9bucuma	23	8	delivered	deliver	VBN
cord-257197-i9bucuma	23	9	using	use	VBG
cord-257197-i9bucuma	23	10	NPs	NPs	NNPS
cord-257197-i9bucuma	23	11	that	that	WDT
cord-257197-i9bucuma	23	12	may	may	MD
cord-257197-i9bucuma	23	13	overcome	overcome	VB
cord-257197-i9bucuma	23	14	these	these	DT
cord-257197-i9bucuma	23	15	shortcomings	shortcoming	NNS
cord-257197-i9bucuma	23	16	by	by	IN
cord-257197-i9bucuma	23	17	improving	improve	VBG
cord-257197-i9bucuma	23	18	their	-PRON-	PRP$
cord-257197-i9bucuma	23	19	half	half	NN
cord-257197-i9bucuma	23	20	-	-	HYPH
cord-257197-i9bucuma	23	21	lives	life	NNS
cord-257197-i9bucuma	23	22	,	,	,
cord-257197-i9bucuma	23	23	stabilities	stability	NNS
cord-257197-i9bucuma	23	24	and	and	CC
cord-257197-i9bucuma	23	25	bioavailabilities	bioavailabilitie	NNS
cord-257197-i9bucuma	23	26	.	.	.
cord-257197-i9bucuma	24	1	17	17	CD
cord-257197-i9bucuma	25	1	However	however	RB
cord-257197-i9bucuma	25	2	,	,	,
cord-257197-i9bucuma	25	3	their	-PRON-	PRP$
cord-257197-i9bucuma	25	4	use	use	NN
cord-257197-i9bucuma	25	5	is	be	VBZ
cord-257197-i9bucuma	25	6	not	not	RB
cord-257197-i9bucuma	25	7	limited	limit	VBN
cord-257197-i9bucuma	25	8	to	to	IN
cord-257197-i9bucuma	25	9	drug	drug	NN
cord-257197-i9bucuma	25	10	delivery	delivery	NN
cord-257197-i9bucuma	25	11	systems	system	NNS
cord-257197-i9bucuma	25	12	(	(	-LRB-
cord-257197-i9bucuma	25	13	DDS	DDS	NNP
cord-257197-i9bucuma	25	14	)	)	-RRB-
cord-257197-i9bucuma	25	15	.	.	.
cord-257197-i9bucuma	26	1	Their	-PRON-	PRP$
cord-257197-i9bucuma	26	2	other	other	JJ
cord-257197-i9bucuma	26	3	applications	application	NNS
cord-257197-i9bucuma	26	4	include	include	VBP
cord-257197-i9bucuma	26	5	use	use	VBP
cord-257197-i9bucuma	26	6	as	as	IN
cord-257197-i9bucuma	26	7	optical	optical	JJ
cord-257197-i9bucuma	26	8	imaging	imaging	NN
cord-257197-i9bucuma	26	9	agents	agent	NNS
cord-257197-i9bucuma	26	10	and	and	CC
cord-257197-i9bucuma	26	11	analytical	analytical	JJ
cord-257197-i9bucuma	26	12	probes	probe	NNS
cord-257197-i9bucuma	26	13	/	/	SYM
cord-257197-i9bucuma	26	14	biosensors	biosensor	NNS
cord-257197-i9bucuma	26	15	,	,	,
cord-257197-i9bucuma	26	16	thus	thus	RB
cord-257197-i9bucuma	26	17	making	make	VBG
cord-257197-i9bucuma	26	18	them	-PRON-	PRP
cord-257197-i9bucuma	26	19	suitable	suitable	JJ
cord-257197-i9bucuma	26	20	theranostics	theranostic	NNS
cord-257197-i9bucuma	26	21	agents	agent	NNS
cord-257197-i9bucuma	26	22	.	.	.
cord-257197-i9bucuma	27	1	[	[	-LRB-
cord-257197-i9bucuma	27	2	18	18	CD
cord-257197-i9bucuma	27	3	]	]	-RRB-
cord-257197-i9bucuma	27	4	[	[	-LRB-
cord-257197-i9bucuma	27	5	19	19	CD
cord-257197-i9bucuma	27	6	]	]	-RRB-
cord-257197-i9bucuma	27	7	[	[	-LRB-
cord-257197-i9bucuma	27	8	20	20	CD
cord-257197-i9bucuma	27	9	]	]	-RRB-
cord-257197-i9bucuma	27	10	[	[	-LRB-
cord-257197-i9bucuma	27	11	21	21	CD
cord-257197-i9bucuma	27	12	]	]	-RRB-
cord-257197-i9bucuma	27	13	Fifty	fifty	CD
cord-257197-i9bucuma	27	14	-	-	HYPH
cord-257197-i9bucuma	27	15	one	one	CD
cord-257197-i9bucuma	27	16	nanomedicines	nanomedicine	NNS
cord-257197-i9bucuma	27	17	have	have	VBP
cord-257197-i9bucuma	27	18	been	be	VBN
cord-257197-i9bucuma	27	19	approved	approve	VBN
cord-257197-i9bucuma	27	20	since	since	IN
cord-257197-i9bucuma	27	21	1995	1995	CD
cord-257197-i9bucuma	27	22	by	by	IN
cord-257197-i9bucuma	27	23	FDA	FDA	NNP
cord-257197-i9bucuma	27	24	for	for	IN
cord-257197-i9bucuma	27	25	clinical	clinical	JJ
cord-257197-i9bucuma	27	26	use	use	NN
cord-257197-i9bucuma	28	1	J	J	NNP
cord-257197-i9bucuma	28	2	o	o	NN
cord-257197-i9bucuma	28	3	u	u	NN
cord-257197-i9bucuma	28	4	r	r	NN
cord-257197-i9bucuma	28	5	n	n	NN
cord-257197-i9bucuma	28	6	a	a	DT
cord-257197-i9bucuma	28	7	l	l	NN
cord-257197-i9bucuma	28	8	P	p	NN
cord-257197-i9bucuma	28	9	r	r	NN
cord-257197-i9bucuma	28	10	e	e	NN
cord-257197-i9bucuma	28	11	-p	-p	NN
cord-257197-i9bucuma	29	1	r	r	LS
cord-257197-i9bucuma	29	2	o	o	NN
cord-257197-i9bucuma	30	1	o	o	UH
cord-257197-i9bucuma	30	2	f	f	NNP
cord-257197-i9bucuma	30	3	with	with	IN
cord-257197-i9bucuma	30	4	~77	~77	CD
cord-257197-i9bucuma	30	5	products	product	NNS
cord-257197-i9bucuma	30	6	in	in	IN
cord-257197-i9bucuma	30	7	clinical	clinical	JJ
cord-257197-i9bucuma	30	8	trials	trial	NNS
cord-257197-i9bucuma	30	9	as	as	IN
cord-257197-i9bucuma	30	10	of	of	IN
cord-257197-i9bucuma	30	11	2016	2016	CD
cord-257197-i9bucuma	30	12	.	.	.
cord-257197-i9bucuma	31	1	22	22	CD
cord-257197-i9bucuma	32	1	Owing	owe	VBG
cord-257197-i9bucuma	32	2	to	to	IN
cord-257197-i9bucuma	32	3	their	-PRON-	PRP$
cord-257197-i9bucuma	32	4	potential	potential	JJ
cord-257197-i9bucuma	32	5	,	,	,
cord-257197-i9bucuma	32	6	nanomaterials	nanomaterial	NNS
cord-257197-i9bucuma	32	7	are	be	VBP
cord-257197-i9bucuma	32	8	being	be	VBG
cord-257197-i9bucuma	32	9	utilized	utilize	VBN
cord-257197-i9bucuma	32	10	in	in	IN
cord-257197-i9bucuma	32	11	the	the	DT
cord-257197-i9bucuma	32	12	recent	recent	JJ
cord-257197-i9bucuma	32	13	fight	fight	NN
cord-257197-i9bucuma	32	14	against	against	IN
cord-257197-i9bucuma	32	15	SARS	SARS	NNP
cord-257197-i9bucuma	32	16	-	-	HYPH
cord-257197-i9bucuma	32	17	CoV-2	CoV-2	NNP
cord-257197-i9bucuma	32	18	.	.	.
cord-257197-i9bucuma	33	1	23	23	CD
cord-257197-i9bucuma	33	2	,	,	,
cord-257197-i9bucuma	33	3	24	24	CD
cord-257197-i9bucuma	33	4	Gold	gold	NN
cord-257197-i9bucuma	33	5	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	33	6	based	base	VBN
cord-257197-i9bucuma	33	7	immunoassays	immunoassay	NNS
cord-257197-i9bucuma	33	8	have	have	VBP
cord-257197-i9bucuma	33	9	been	be	VBN
cord-257197-i9bucuma	33	10	developed	develop	VBN
cord-257197-i9bucuma	33	11	that	that	WDT
cord-257197-i9bucuma	33	12	enable	enable	VB
cord-257197-i9bucuma	33	13	rapid	rapid	JJ
cord-257197-i9bucuma	33	14	detection	detection	NN
cord-257197-i9bucuma	33	15	of	of	IN
cord-257197-i9bucuma	33	16	SARS	SARS	NNP
cord-257197-i9bucuma	33	17	-	-	HYPH
cord-257197-i9bucuma	33	18	CoV-2	CoV-2	NNP
cord-257197-i9bucuma	33	19	infected	infect	VBD
cord-257197-i9bucuma	33	20	asymptomatic	asymptomatic	JJ
cord-257197-i9bucuma	33	21	patients	patient	NNS
cord-257197-i9bucuma	33	22	or	or	CC
cord-257197-i9bucuma	33	23	individuals	individual	NNS
cord-257197-i9bucuma	33	24	showing	show	VBG
cord-257197-i9bucuma	33	25	mild	mild	JJ
cord-257197-i9bucuma	33	26	symptoms	symptom	NNS
cord-257197-i9bucuma	33	27	.	.	.
cord-257197-i9bucuma	34	1	25	25	CD
cord-257197-i9bucuma	34	2	,	,	,
cord-257197-i9bucuma	34	3	26	26	CD
cord-257197-i9bucuma	35	1	An	an	DT
cord-257197-i9bucuma	35	2	mRNA	mRNA	NNP
cord-257197-i9bucuma	35	3	vaccine	vaccine	NN
cord-257197-i9bucuma	35	4	which	which	WDT
cord-257197-i9bucuma	35	5	went	go	VBD
cord-257197-i9bucuma	35	6	into	into	IN
cord-257197-i9bucuma	35	7	Phase	phase	NN
cord-257197-i9bucuma	35	8	1	1	CD
cord-257197-i9bucuma	35	9	clinical	clinical	JJ
cord-257197-i9bucuma	35	10	trial	trial	NN
cord-257197-i9bucuma	35	11	in	in	IN
cord-257197-i9bucuma	35	12	March	March	NNP
cord-257197-i9bucuma	35	13	2020	2020	CD
cord-257197-i9bucuma	35	14	,	,	,
cord-257197-i9bucuma	35	15	codes	code	NNS
cord-257197-i9bucuma	35	16	for	for	IN
cord-257197-i9bucuma	35	17	the	the	DT
cord-257197-i9bucuma	35	18	prefusion	prefusion	NN
cord-257197-i9bucuma	35	19	stabilized	stabilize	VBD
cord-257197-i9bucuma	35	20	spike	spike	NN
cord-257197-i9bucuma	35	21	protein	protein	NN
cord-257197-i9bucuma	35	22	of	of	IN
cord-257197-i9bucuma	36	1	SARS	SARS	NNP
cord-257197-i9bucuma	36	2	-	-	HYPH
cord-257197-i9bucuma	36	3	Cov-2	Cov-2	NNP
cord-257197-i9bucuma	36	4	and	and	CC
cord-257197-i9bucuma	36	5	it	-PRON-	PRP
cord-257197-i9bucuma	36	6	is	be	VBZ
cord-257197-i9bucuma	36	7	encapsulated	encapsulate	VBN
cord-257197-i9bucuma	36	8	in	in	IN
cord-257197-i9bucuma	36	9	lipid	lipid	NN
cord-257197-i9bucuma	36	10	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	36	11	which	which	WDT
cord-257197-i9bucuma	36	12	serve	serve	VBP
cord-257197-i9bucuma	36	13	as	as	IN
cord-257197-i9bucuma	36	14	effective	effective	JJ
cord-257197-i9bucuma	36	15	delivery	delivery	NN
cord-257197-i9bucuma	36	16	agents	agent	NNS
cord-257197-i9bucuma	36	17	.	.	.
cord-257197-i9bucuma	37	1	27	27	CD
cord-257197-i9bucuma	38	1	The	the	DT
cord-257197-i9bucuma	38	2	focus	focus	NN
cord-257197-i9bucuma	38	3	of	of	IN
cord-257197-i9bucuma	38	4	this	this	DT
cord-257197-i9bucuma	38	5	review	review	NN
cord-257197-i9bucuma	38	6	is	be	VBZ
cord-257197-i9bucuma	38	7	on	on	IN
cord-257197-i9bucuma	38	8	gold	gold	NN
cord-257197-i9bucuma	38	9	and	and	CC
cord-257197-i9bucuma	38	10	iron	iron	NN
cord-257197-i9bucuma	38	11	oxide	oxide	NN
cord-257197-i9bucuma	38	12	NPs	NPs	NNP
cord-257197-i9bucuma	38	13	which	which	WDT
cord-257197-i9bucuma	38	14	are	be	VBP
cord-257197-i9bucuma	38	15	the	the	DT
cord-257197-i9bucuma	38	16	top	top	JJ
cord-257197-i9bucuma	38	17	2	2	CD
cord-257197-i9bucuma	38	18	inorganic	inorganic	JJ
cord-257197-i9bucuma	38	19	NPs	np	NNS
cord-257197-i9bucuma	38	20	in	in	IN
cord-257197-i9bucuma	38	21	clinical	clinical	JJ
cord-257197-i9bucuma	38	22	trials	trial	NNS
cord-257197-i9bucuma	39	1	(	(	-LRB-
cord-257197-i9bucuma	39	2	Fig	Fig	NNP
cord-257197-i9bucuma	39	3	.	.	.
cord-257197-i9bucuma	39	4	1D	1d	CD
cord-257197-i9bucuma	39	5	)	)	-RRB-
cord-257197-i9bucuma	39	6	.	.	.
cord-257197-i9bucuma	40	1	Iron	iron	NN
cord-257197-i9bucuma	40	2	oxide	oxide	NN
cord-257197-i9bucuma	40	3	NPs	NPs	NNP
cord-257197-i9bucuma	40	4	are	be	VBP
cord-257197-i9bucuma	40	5	the	the	DT
cord-257197-i9bucuma	40	6	only	only	JJ
cord-257197-i9bucuma	40	7	metal	metal	NN
cord-257197-i9bucuma	40	8	-	-	HYPH
cord-257197-i9bucuma	40	9	containing	contain	VBG
cord-257197-i9bucuma	40	10	NPs	NPs	NNPS
cord-257197-i9bucuma	40	11	that	that	WDT
cord-257197-i9bucuma	40	12	have	have	VBP
cord-257197-i9bucuma	40	13	received	receive	VBN
cord-257197-i9bucuma	40	14	approval	approval	NN
cord-257197-i9bucuma	40	15	to	to	IN
cord-257197-i9bucuma	40	16	date	date	NN
cord-257197-i9bucuma	40	17	for	for	IN
cord-257197-i9bucuma	40	18	clinical	clinical	JJ
cord-257197-i9bucuma	40	19	use	use	NN
cord-257197-i9bucuma	40	20	and	and	CC
cord-257197-i9bucuma	40	21	most	most	JJS
cord-257197-i9bucuma	40	22	of	of	IN
cord-257197-i9bucuma	40	23	them	-PRON-	PRP
cord-257197-i9bucuma	40	24	are	be	VBP
cord-257197-i9bucuma	40	25	MRI	MRI	NNP
cord-257197-i9bucuma	40	26	contrast	contrast	NN
cord-257197-i9bucuma	40	27	agents	agent	NNS
cord-257197-i9bucuma	40	28	.	.	.
cord-257197-i9bucuma	41	1	22	22	CD
cord-257197-i9bucuma	41	2	Gold	gold	NN
cord-257197-i9bucuma	41	3	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	41	4	(	(	-LRB-
cord-257197-i9bucuma	41	5	AuNPs	AuNPs	JJS
cord-257197-i9bucuma	41	6	)	)	-RRB-
cord-257197-i9bucuma	41	7	exhibit	exhibit	VB
cord-257197-i9bucuma	41	8	plasmon	plasmon	JJ
cord-257197-i9bucuma	41	9	resonance	resonance	NN
cord-257197-i9bucuma	41	10	which	which	WDT
cord-257197-i9bucuma	41	11	can	can	MD
cord-257197-i9bucuma	41	12	be	be	VB
cord-257197-i9bucuma	41	13	followed	follow	VBN
cord-257197-i9bucuma	41	14	using	use	VBG
cord-257197-i9bucuma	41	15	UV	uv	NN
cord-257197-i9bucuma	41	16	-	-	HYPH
cord-257197-i9bucuma	41	17	Vis	vis	FW
cord-257197-i9bucuma	41	18	spectrophotometric	spectrophotometric	JJ
cord-257197-i9bucuma	41	19	detection	detection	NN
cord-257197-i9bucuma	41	20	assays	assay	NNS
cord-257197-i9bucuma	41	21	28	28	CD
cord-257197-i9bucuma	41	22	,	,	,
cord-257197-i9bucuma	41	23	29	29	CD
cord-257197-i9bucuma	41	24	,	,	,
cord-257197-i9bucuma	41	25	surface	surface	NN
cord-257197-i9bucuma	41	26	-	-	HYPH
cord-257197-i9bucuma	41	27	enhanced	enhance	VBN
cord-257197-i9bucuma	41	28	Raman	Raman	NNP
cord-257197-i9bucuma	41	29	spectroscopy	spectroscopy	NN
cord-257197-i9bucuma	41	30	(	(	-LRB-
cord-257197-i9bucuma	41	31	SERS	SERS	NNP
cord-257197-i9bucuma	41	32	)	)	-RRB-
cord-257197-i9bucuma	41	33	30	30	CD
cord-257197-i9bucuma	41	34	and	and	CC
cord-257197-i9bucuma	41	35	confocal/	confocal/	NNS
cord-257197-i9bucuma	41	36	luminescence	luminescence	NN
cord-257197-i9bucuma	41	37	microscopy	microscopy	NN
cord-257197-i9bucuma	41	38	.	.	.
cord-257197-i9bucuma	42	1	31	31	CD
cord-257197-i9bucuma	42	2	,	,	,
cord-257197-i9bucuma	42	3	32	32	CD
cord-257197-i9bucuma	43	1	The	the	DT
cord-257197-i9bucuma	43	2	magnetic	magnetic	JJ
cord-257197-i9bucuma	43	3	iron	iron	NN
cord-257197-i9bucuma	43	4	oxide	oxide	NN
cord-257197-i9bucuma	43	5	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	43	6	(	(	-LRB-
cord-257197-i9bucuma	43	7	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	43	8	)	)	-RRB-
cord-257197-i9bucuma	43	9	,	,	,
cord-257197-i9bucuma	43	10	also	also	RB
cord-257197-i9bucuma	43	11	commonly	commonly	RB
cord-257197-i9bucuma	43	12	called	call	VBN
cord-257197-i9bucuma	43	13	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	43	14	iron	iron	NN
cord-257197-i9bucuma	43	15	oxide	oxide	NN
cord-257197-i9bucuma	43	16	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	43	17	(	(	-LRB-
cord-257197-i9bucuma	43	18	SPIONs	spion	NNS
cord-257197-i9bucuma	43	19	)	)	-RRB-
cord-257197-i9bucuma	43	20	are	be	VBP
cord-257197-i9bucuma	43	21	used	use	VBN
cord-257197-i9bucuma	43	22	as	as	IN
cord-257197-i9bucuma	43	23	contrast	contrast	NN
cord-257197-i9bucuma	43	24	agents	agent	NNS
cord-257197-i9bucuma	43	25	for	for	IN
cord-257197-i9bucuma	43	26	magnetic	magnetic	JJ
cord-257197-i9bucuma	43	27	resonance	resonance	NN
cord-257197-i9bucuma	43	28	imaging	imaging	NN
cord-257197-i9bucuma	43	29	(	(	-LRB-
cord-257197-i9bucuma	43	30	MRI	MRI	NNP
cord-257197-i9bucuma	43	31	)	)	-RRB-
cord-257197-i9bucuma	43	32	33	33	CD
cord-257197-i9bucuma	43	33	,	,	,
cord-257197-i9bucuma	43	34	34	34	CD
cord-257197-i9bucuma	43	35	,	,	,
cord-257197-i9bucuma	43	36	for	for	IN
cord-257197-i9bucuma	43	37	bio	bio	NN
cord-257197-i9bucuma	43	38	-	-	NN
cord-257197-i9bucuma	43	39	detection	detection	NN
cord-257197-i9bucuma	43	40	such	such	JJ
cord-257197-i9bucuma	43	41	as	as	IN
cord-257197-i9bucuma	43	42	tracking	track	VBG
cord-257197-i9bucuma	43	43	the	the	DT
cord-257197-i9bucuma	43	44	implanted	implant	VBN
cord-257197-i9bucuma	43	45	stem	stem	NN
cord-257197-i9bucuma	43	46	cells	cell	NNS
cord-257197-i9bucuma	43	47	in	in	IN
cord-257197-i9bucuma	43	48	vitro	vitro	NNP
cord-257197-i9bucuma	43	49	35	35	CD
cord-257197-i9bucuma	43	50	,	,	,
cord-257197-i9bucuma	43	51	in	in	IN
cord-257197-i9bucuma	43	52	binding	bind	VBG
cord-257197-i9bucuma	43	53	assays	assay	NNS
cord-257197-i9bucuma	43	54	and	and	CC
cord-257197-i9bucuma	43	55	hyperthermia	hyperthermia	NN
cord-257197-i9bucuma	43	56	36	36	CD
cord-257197-i9bucuma	43	57	,	,	,
cord-257197-i9bucuma	43	58	37	37	CD
cord-257197-i9bucuma	43	59	and	and	CC
cord-257197-i9bucuma	43	60	magnetic	magnetic	JJ
cord-257197-i9bucuma	43	61	field	field	NN
cord-257197-i9bucuma	43	62	guided	guide	VBD
cord-257197-i9bucuma	43	63	drug	drug	NN
cord-257197-i9bucuma	43	64	delivery	delivery	NN
cord-257197-i9bucuma	43	65	21	21	CD
cord-257197-i9bucuma	43	66	in	in	IN
cord-257197-i9bucuma	43	67	cancer	cancer	NN
cord-257197-i9bucuma	43	68	treatment	treatment	NN
cord-257197-i9bucuma	43	69	.	.	.
cord-257197-i9bucuma	44	1	Besides	besides	RB
cord-257197-i9bucuma	44	2	,	,	,
cord-257197-i9bucuma	44	3	the	the	DT
cord-257197-i9bucuma	44	4	electron	electron	NN
cord-257197-i9bucuma	44	5	dense	dense	JJ
cord-257197-i9bucuma	44	6	gold	gold	NN
cord-257197-i9bucuma	44	7	and	and	CC
cord-257197-i9bucuma	44	8	iron	iron	NN
cord-257197-i9bucuma	44	9	NPs	np	NNS
cord-257197-i9bucuma	44	10	are	be	VBP
cord-257197-i9bucuma	44	11	used	use	VBN
cord-257197-i9bucuma	44	12	widely	widely	RB
cord-257197-i9bucuma	44	13	in	in	IN
cord-257197-i9bucuma	44	14	electron	electron	NN
cord-257197-i9bucuma	44	15	microscopy	microscopy	NN
cord-257197-i9bucuma	44	16	analyses	analysis	NNS
cord-257197-i9bucuma	44	17	.	.	.
cord-257197-i9bucuma	45	1	Au	Au	NNP
cord-257197-i9bucuma	45	2	-	-	HYPH
cord-257197-i9bucuma	45	3	Magnetite	Magnetite	NNP
cord-257197-i9bucuma	45	4	composites	composite	NNS
cord-257197-i9bucuma	45	5	used	use	VBN
cord-257197-i9bucuma	45	6	in	in	IN
cord-257197-i9bucuma	45	7	(	(	-LRB-
cord-257197-i9bucuma	45	8	SERS	SERS	NNP
cord-257197-i9bucuma	45	9	)	)	-RRB-
cord-257197-i9bucuma	46	1	analyses	analysis	NNS
cord-257197-i9bucuma	46	2	improve	improve	VBP
cord-257197-i9bucuma	46	3	the	the	DT
cord-257197-i9bucuma	46	4	intracellular	intracellular	JJ
cord-257197-i9bucuma	46	5	signal	signal	NN
cord-257197-i9bucuma	46	6	intensity	intensity	NN
cord-257197-i9bucuma	46	7	essential	essential	JJ
cord-257197-i9bucuma	46	8	to	to	IN
cord-257197-i9bucuma	46	9	studying	study	VBG
cord-257197-i9bucuma	46	10	interactions	interaction	NNS
cord-257197-i9bucuma	46	11	of	of	IN
cord-257197-i9bucuma	46	12	NPs	NPs	NNPS
cord-257197-i9bucuma	46	13	with	with	IN
cord-257197-i9bucuma	46	14	biomolecules	biomolecule	NNS
cord-257197-i9bucuma	46	15	.	.	.
cord-257197-i9bucuma	47	1	30	30	CD
cord-257197-i9bucuma	47	2	Delivery	delivery	NN
cord-257197-i9bucuma	47	3	systems	system	NNS
cord-257197-i9bucuma	47	4	must	must	MD
cord-257197-i9bucuma	47	5	be	be	VB
cord-257197-i9bucuma	47	6	non	non	JJ
cord-257197-i9bucuma	47	7	-	-	JJ
cord-257197-i9bucuma	47	8	toxic	toxic	JJ
cord-257197-i9bucuma	47	9	by	by	IN
cord-257197-i9bucuma	47	10	themselves	-PRON-	PRP
cord-257197-i9bucuma	47	11	,	,	,
cord-257197-i9bucuma	47	12	should	should	MD
cord-257197-i9bucuma	47	13	not	not	RB
cord-257197-i9bucuma	47	14	be	be	VB
cord-257197-i9bucuma	47	15	cleared	clear	VBN
cord-257197-i9bucuma	47	16	quickly	quickly	RB
cord-257197-i9bucuma	47	17	from	from	IN
cord-257197-i9bucuma	47	18	the	the	DT
cord-257197-i9bucuma	47	19	body	body	NN
cord-257197-i9bucuma	47	20	and	and	CC
cord-257197-i9bucuma	47	21	trigger	trigger	VB
cord-257197-i9bucuma	47	22	adverse	adverse	JJ
cord-257197-i9bucuma	47	23	immunological	immunological	JJ
cord-257197-i9bucuma	47	24	responses	response	NNS
cord-257197-i9bucuma	47	25	.	.	.
cord-257197-i9bucuma	48	1	It	-PRON-	PRP
cord-257197-i9bucuma	48	2	,	,	,
cord-257197-i9bucuma	48	3	therefore	therefore	RB
cord-257197-i9bucuma	48	4	,	,	,
cord-257197-i9bucuma	48	5	becomes	become	VBZ
cord-257197-i9bucuma	48	6	vital	vital	JJ
cord-257197-i9bucuma	48	7	to	to	TO
cord-257197-i9bucuma	48	8	understand	understand	VB
cord-257197-i9bucuma	48	9	J	J	NNP
cord-257197-i9bucuma	48	10	o	o	NN
cord-257197-i9bucuma	48	11	u	u	NN
cord-257197-i9bucuma	48	12	r	r	NN
cord-257197-i9bucuma	48	13	n	n	NN
cord-257197-i9bucuma	49	1	a	a	DT
cord-257197-i9bucuma	49	2	l	l	NN
cord-257197-i9bucuma	49	3	P	p	NN
cord-257197-i9bucuma	49	4	r	r	NN
cord-257197-i9bucuma	49	5	e	e	NN
cord-257197-i9bucuma	49	6	-p	-p	NN
cord-257197-i9bucuma	49	7	r	r	NN
cord-257197-i9bucuma	49	8	o	o	NN
cord-257197-i9bucuma	49	9	o	o	NN
cord-257197-i9bucuma	49	10	f	f	XX
cord-257197-i9bucuma	49	11	their	-PRON-	PRP$
cord-257197-i9bucuma	49	12	interactions	interaction	NNS
cord-257197-i9bucuma	49	13	at	at	IN
cord-257197-i9bucuma	49	14	a	a	DT
cord-257197-i9bucuma	49	15	molecular	molecular	JJ
cord-257197-i9bucuma	49	16	level	level	NN
cord-257197-i9bucuma	49	17	,	,	,
cord-257197-i9bucuma	49	18	to	to	TO
cord-257197-i9bucuma	49	19	determine	determine	VB
cord-257197-i9bucuma	49	20	how	how	WRB
cord-257197-i9bucuma	49	21	suitable	suitable	JJ
cord-257197-i9bucuma	49	22	they	-PRON-	PRP
cord-257197-i9bucuma	49	23	are	be	VBP
cord-257197-i9bucuma	49	24	for	for	IN
cord-257197-i9bucuma	49	25	delivery	delivery	NN
cord-257197-i9bucuma	49	26	and	and	CC
cord-257197-i9bucuma	49	27	determine	determine	VB
cord-257197-i9bucuma	49	28	the	the	DT
cord-257197-i9bucuma	49	29	applications	application	NNS
cord-257197-i9bucuma	49	30	for	for	IN
cord-257197-i9bucuma	49	31	which	which	WDT
cord-257197-i9bucuma	49	32	they	-PRON-	PRP
cord-257197-i9bucuma	49	33	are	be	VBP
cord-257197-i9bucuma	49	34	best	well	RBS
cord-257197-i9bucuma	49	35	suited	suited	JJ
cord-257197-i9bucuma	49	36	.	.	.
cord-257197-i9bucuma	50	1	The	the	DT
cord-257197-i9bucuma	50	2	review	review	NN
cord-257197-i9bucuma	50	3	is	be	VBZ
cord-257197-i9bucuma	50	4	divided	divide	VBN
cord-257197-i9bucuma	50	5	into	into	IN
cord-257197-i9bucuma	50	6	four	four	CD
cord-257197-i9bucuma	50	7	sections	section	NNS
cord-257197-i9bucuma	50	8	which	which	WDT
cord-257197-i9bucuma	50	9	discuss	discuss	VBP
cord-257197-i9bucuma	50	10	the	the	DT
cord-257197-i9bucuma	50	11	(	(	-LRB-
cord-257197-i9bucuma	50	12	I	i	NN
cord-257197-i9bucuma	50	13	)	)	-RRB-
cord-257197-i9bucuma	50	14	synthesis	synthesis	NN
cord-257197-i9bucuma	50	15	and	and	CC
cord-257197-i9bucuma	50	16	functionalizing	functionalizing	NN
cord-257197-i9bucuma	50	17	of	of	IN
cord-257197-i9bucuma	50	18	NPs	NPs	NNP
cord-257197-i9bucuma	50	19	,	,	,
cord-257197-i9bucuma	50	20	(	(	-LRB-
cord-257197-i9bucuma	50	21	II	II	NNP
cord-257197-i9bucuma	50	22	)	)	-RRB-
cord-257197-i9bucuma	51	1	the	the	DT
cord-257197-i9bucuma	51	2	discrepancies	discrepancy	NNS
cord-257197-i9bucuma	51	3	observed	observe	VBN
cord-257197-i9bucuma	51	4	between	between	IN
cord-257197-i9bucuma	51	5	the	the	DT
cord-257197-i9bucuma	51	6	effects	effect	NNS
cord-257197-i9bucuma	51	7	of	of	IN
cord-257197-i9bucuma	51	8	NPs	NPs	NNPS
cord-257197-i9bucuma	51	9	in	in	IN
cord-257197-i9bucuma	51	10	vitro	vitro	FW
cord-257197-i9bucuma	51	11	and	and	CC
cord-257197-i9bucuma	51	12	in	in	IN
cord-257197-i9bucuma	51	13	vivo	vivo	NN
cord-257197-i9bucuma	51	14	,	,	,
cord-257197-i9bucuma	51	15	followed	follow	VBN
cord-257197-i9bucuma	51	16	by	by	IN
cord-257197-i9bucuma	51	17	a	a	DT
cord-257197-i9bucuma	51	18	detailed	detailed	JJ
cord-257197-i9bucuma	51	19	review	review	NN
cord-257197-i9bucuma	51	20	of	of	IN
cord-257197-i9bucuma	51	21	(	(	-LRB-
cord-257197-i9bucuma	51	22	III	III	NNP
cord-257197-i9bucuma	51	23	)	)	-RRB-
cord-257197-i9bucuma	51	24	in	in	IN
cord-257197-i9bucuma	51	25	vitro	vitro	FW
cord-257197-i9bucuma	51	26	and	and	CC
cord-257197-i9bucuma	51	27	(	(	-LRB-
cord-257197-i9bucuma	51	28	IV	IV	NNP
cord-257197-i9bucuma	51	29	)	)	-RRB-
cord-257197-i9bucuma	51	30	in	in	IN
cord-257197-i9bucuma	51	31	vivo	vivo	NNP
cord-257197-i9bucuma	51	32	studies	study	NNS
cord-257197-i9bucuma	51	33	of	of	IN
cord-257197-i9bucuma	51	34	gold	gold	NN
cord-257197-i9bucuma	51	35	and	and	CC
cord-257197-i9bucuma	51	36	iron	iron	NN
cord-257197-i9bucuma	51	37	oxide	oxide	NN
cord-257197-i9bucuma	51	38	NPs	NPs	NNP
cord-257197-i9bucuma	51	39	,	,	,
cord-257197-i9bucuma	51	40	which	which	WDT
cord-257197-i9bucuma	51	41	demonstrate	demonstrate	VBP
cord-257197-i9bucuma	51	42	the	the	DT
cord-257197-i9bucuma	51	43	need	need	NN
cord-257197-i9bucuma	51	44	to	to	TO
cord-257197-i9bucuma	51	45	carefully	carefully	RB
cord-257197-i9bucuma	51	46	consider	consider	VB
cord-257197-i9bucuma	51	47	experimental	experimental	JJ
cord-257197-i9bucuma	51	48	factors	factor	NNS
cord-257197-i9bucuma	51	49	to	to	TO
cord-257197-i9bucuma	51	50	improve	improve	VB
cord-257197-i9bucuma	51	51	the	the	DT
cord-257197-i9bucuma	51	52	correlation	correlation	NN
cord-257197-i9bucuma	51	53	between	between	IN
cord-257197-i9bucuma	51	54	in	in	IN
cord-257197-i9bucuma	51	55	vitro	vitro	FW
cord-257197-i9bucuma	51	56	and	and	CC
cord-257197-i9bucuma	51	57	in	in	IN
cord-257197-i9bucuma	51	58	vivo	vivo	NNP
cord-257197-i9bucuma	51	59	studies	study	NNS
cord-257197-i9bucuma	51	60	.	.	.
cord-257197-i9bucuma	52	1	This	this	DT
cord-257197-i9bucuma	52	2	review	review	NN
cord-257197-i9bucuma	52	3	also	also	RB
cord-257197-i9bucuma	52	4	presents	present	VBZ
cord-257197-i9bucuma	52	5	recent	recent	JJ
cord-257197-i9bucuma	52	6	in	in	IN
cord-257197-i9bucuma	52	7	vitro	vitro	FW
cord-257197-i9bucuma	52	8	and	and	CC
cord-257197-i9bucuma	52	9	in	in	IN
cord-257197-i9bucuma	52	10	vivo	vivo	NNP
cord-257197-i9bucuma	52	11	studies	study	NNS
cord-257197-i9bucuma	52	12	that	that	WDT
cord-257197-i9bucuma	52	13	assess	assess	VBP
cord-257197-i9bucuma	52	14	the	the	DT
cord-257197-i9bucuma	52	15	biosafety	biosafety	NN
cord-257197-i9bucuma	52	16	/	/	SYM
cord-257197-i9bucuma	52	17	toxicity	toxicity	NN
cord-257197-i9bucuma	52	18	of	of	IN
cord-257197-i9bucuma	52	19	NPs	NPs	NNPS
cord-257197-i9bucuma	52	20	and	and	CC
cord-257197-i9bucuma	52	21	the	the	DT
cord-257197-i9bucuma	52	22	influence	influence	NN
cord-257197-i9bucuma	52	23	of	of	IN
cord-257197-i9bucuma	52	24	surface	surface	NN
cord-257197-i9bucuma	52	25	ligands	ligand	NNS
cord-257197-i9bucuma	52	26	on	on	IN
cord-257197-i9bucuma	52	27	nano	nano	NNP
cord-257197-i9bucuma	52	28	-	-	HYPH
cord-257197-i9bucuma	52	29	bio	bio	JJ
cord-257197-i9bucuma	52	30	interactions	interaction	NNS
cord-257197-i9bucuma	52	31	such	such	JJ
cord-257197-i9bucuma	52	32	as	as	IN
cord-257197-i9bucuma	52	33	uptake	uptake	NN
cord-257197-i9bucuma	52	34	and	and	CC
cord-257197-i9bucuma	52	35	immune	immune	JJ
cord-257197-i9bucuma	52	36	response	response	NN
cord-257197-i9bucuma	52	37	.	.	.
cord-257197-i9bucuma	53	1	We	-PRON-	PRP
cord-257197-i9bucuma	53	2	will	will	MD
cord-257197-i9bucuma	53	3	emphasize	emphasize	VB
cord-257197-i9bucuma	53	4	the	the	DT
cord-257197-i9bucuma	53	5	importance	importance	NN
cord-257197-i9bucuma	53	6	of	of	IN
cord-257197-i9bucuma	53	7	standardization	standardization	NN
cord-257197-i9bucuma	53	8	in	in	IN
cord-257197-i9bucuma	53	9	nanotechnology	nanotechnology	NN
cord-257197-i9bucuma	53	10	with	with	IN
cord-257197-i9bucuma	53	11	a	a	DT
cord-257197-i9bucuma	53	12	focus	focus	NN
cord-257197-i9bucuma	53	13	on	on	IN
cord-257197-i9bucuma	53	14	the	the	DT
cord-257197-i9bucuma	53	15	experimental	experimental	JJ
cord-257197-i9bucuma	53	16	parameters	parameter	NNS
cord-257197-i9bucuma	53	17	since	since	IN
cord-257197-i9bucuma	53	18	they	-PRON-	PRP
cord-257197-i9bucuma	53	19	have	have	VBP
cord-257197-i9bucuma	53	20	a	a	DT
cord-257197-i9bucuma	53	21	significant	significant	JJ
cord-257197-i9bucuma	53	22	impact	impact	NN
cord-257197-i9bucuma	53	23	on	on	IN
cord-257197-i9bucuma	53	24	the	the	DT
cord-257197-i9bucuma	53	25	outcome	outcome	NN
cord-257197-i9bucuma	53	26	of	of	IN
cord-257197-i9bucuma	53	27	studies	study	NNS
cord-257197-i9bucuma	53	28	.	.	.
cord-257197-i9bucuma	54	1	Standardization	standardization	NN
cord-257197-i9bucuma	54	2	is	be	VBZ
cord-257197-i9bucuma	54	3	essential	essential	JJ
cord-257197-i9bucuma	54	4	to	to	TO
cord-257197-i9bucuma	54	5	make	make	VB
cord-257197-i9bucuma	54	6	valid	valid	JJ
cord-257197-i9bucuma	54	7	comparisons	comparison	NNS
cord-257197-i9bucuma	54	8	between	between	IN
cord-257197-i9bucuma	54	9	studies	study	NNS
cord-257197-i9bucuma	54	10	and	and	CC
cord-257197-i9bucuma	54	11	to	to	TO
cord-257197-i9bucuma	54	12	prevent	prevent	VB
cord-257197-i9bucuma	54	13	redundancy	redundancy	NN
cord-257197-i9bucuma	54	14	in	in	IN
cord-257197-i9bucuma	54	15	research	research	NN
cord-257197-i9bucuma	54	16	which	which	WDT
cord-257197-i9bucuma	54	17	help	help	VBP
cord-257197-i9bucuma	54	18	develop	develop	VB
cord-257197-i9bucuma	54	19	the	the	DT
cord-257197-i9bucuma	54	20	field	field	NN
cord-257197-i9bucuma	54	21	of	of	IN
cord-257197-i9bucuma	54	22	nanomedicine	nanomedicine	NN
cord-257197-i9bucuma	54	23	.	.	.
cord-257197-i9bucuma	55	1	38	38	CD
cord-257197-i9bucuma	55	2	,	,	,
cord-257197-i9bucuma	55	3	39	39	CD
cord-257197-i9bucuma	55	4	J	j	NN
cord-257197-i9bucuma	55	5	o	o	NN
cord-257197-i9bucuma	55	6	u	u	NN
cord-257197-i9bucuma	55	7	r	r	NN
cord-257197-i9bucuma	55	8	n	n	NN
cord-257197-i9bucuma	55	9	a	a	DT
cord-257197-i9bucuma	55	10	l	l	NN
cord-257197-i9bucuma	55	11	P	p	NN
cord-257197-i9bucuma	55	12	r	r	NN
cord-257197-i9bucuma	55	13	e	e	NN
cord-257197-i9bucuma	55	14	-p	-p	NN
cord-257197-i9bucuma	56	1	r	r	NN
cord-257197-i9bucuma	56	2	o	o	NN
cord-257197-i9bucuma	56	3	o	o	NN
cord-257197-i9bucuma	56	4	f	f	NN
cord-257197-i9bucuma	57	1	The	the	DT
cord-257197-i9bucuma	57	2	basic	basic	JJ
cord-257197-i9bucuma	57	3	principle	principle	NN
cord-257197-i9bucuma	57	4	of	of	IN
cord-257197-i9bucuma	57	5	NPs	NPs	NNP
cord-257197-i9bucuma	57	6	syntheses	synthesis	NNS
cord-257197-i9bucuma	57	7	is	be	VBZ
cord-257197-i9bucuma	57	8	to	to	TO
cord-257197-i9bucuma	57	9	promote	promote	VB
cord-257197-i9bucuma	57	10	nucleation	nucleation	NN
cord-257197-i9bucuma	57	11	of	of	IN
cord-257197-i9bucuma	57	12	the	the	DT
cord-257197-i9bucuma	57	13	monomeric	monomeric	JJ
cord-257197-i9bucuma	57	14	element	element	NN
cord-257197-i9bucuma	57	15	(	(	-LRB-
cord-257197-i9bucuma	57	16	e.g.	e.g.	IN
cord-257197-i9bucuma	57	17	lipids	lipid	NNS
cord-257197-i9bucuma	57	18	for	for	IN
cord-257197-i9bucuma	57	19	liposomes	liposome	NNS
cord-257197-i9bucuma	57	20	and	and	CC
cord-257197-i9bucuma	57	21	metal	metal	NN
cord-257197-i9bucuma	57	22	ions	ion	NNS
cord-257197-i9bucuma	57	23	for	for	IN
cord-257197-i9bucuma	57	24	inorganic	inorganic	JJ
cord-257197-i9bucuma	57	25	metal	metal	NN
cord-257197-i9bucuma	57	26	NPs	NPs	NNP
cord-257197-i9bucuma	57	27	)	)	-RRB-
cord-257197-i9bucuma	57	28	,	,	,
cord-257197-i9bucuma	57	29	facilitating	facilitate	VBG
cord-257197-i9bucuma	57	30	their	-PRON-	PRP$
cord-257197-i9bucuma	57	31	assembly	assembly	NN
cord-257197-i9bucuma	57	32	in	in	IN
cord-257197-i9bucuma	57	33	a	a	DT
cord-257197-i9bucuma	57	34	controlled	control	VBN
cord-257197-i9bucuma	57	35	manner	manner	NN
cord-257197-i9bucuma	57	36	to	to	TO
cord-257197-i9bucuma	57	37	form	form	VB
cord-257197-i9bucuma	57	38	stable	stable	JJ
cord-257197-i9bucuma	57	39	and	and	CC
cord-257197-i9bucuma	57	40	well	well	RB
cord-257197-i9bucuma	57	41	-	-	HYPH
cord-257197-i9bucuma	57	42	structured	structure	VBN
cord-257197-i9bucuma	57	43	entities	entity	NNS
cord-257197-i9bucuma	57	44	with	with	IN
cord-257197-i9bucuma	57	45	narrow	narrow	JJ
cord-257197-i9bucuma	57	46	size	size	NN
cord-257197-i9bucuma	57	47	distributions	distribution	NNS
cord-257197-i9bucuma	57	48	.	.	.
cord-257197-i9bucuma	58	1	Multiple	multiple	JJ
cord-257197-i9bucuma	58	2	routes	route	NNS
cord-257197-i9bucuma	58	3	and	and	CC
cord-257197-i9bucuma	58	4	techniques	technique	NNS
cord-257197-i9bucuma	58	5	used	use	VBN
cord-257197-i9bucuma	58	6	in	in	IN
cord-257197-i9bucuma	58	7	NP	NP	NNP
cord-257197-i9bucuma	58	8	syntheses	synthesis	NNS
cord-257197-i9bucuma	58	9	have	have	VBP
cord-257197-i9bucuma	58	10	been	be	VBN
cord-257197-i9bucuma	58	11	established	establish	VBN
cord-257197-i9bucuma	58	12	that	that	WDT
cord-257197-i9bucuma	58	13	are	be	VBP
cord-257197-i9bucuma	58	14	broadly	broadly	RB
cord-257197-i9bucuma	58	15	categorized	categorize	VBN
cord-257197-i9bucuma	58	16	as	as	IN
cord-257197-i9bucuma	58	17	chemical	chemical	NN
cord-257197-i9bucuma	58	18	,	,	,
cord-257197-i9bucuma	58	19	physical	physical	JJ
cord-257197-i9bucuma	58	20	and	and	CC
cord-257197-i9bucuma	58	21	biological	biological	JJ
cord-257197-i9bucuma	58	22	.	.	.
cord-257197-i9bucuma	59	1	Most	Most	JJS
cord-257197-i9bucuma	59	2	chemical	chemical	JJ
cord-257197-i9bucuma	59	3	and	and	CC
cord-257197-i9bucuma	59	4	biological	biological	JJ
cord-257197-i9bucuma	59	5	methods	method	NNS
cord-257197-i9bucuma	59	6	use	use	VBP
cord-257197-i9bucuma	59	7	facile	facile	JJ
cord-257197-i9bucuma	59	8	synthesis	synthesis	NN
cord-257197-i9bucuma	59	9	techniques	technique	NNS
cord-257197-i9bucuma	59	10	that	that	WDT
cord-257197-i9bucuma	59	11	are	be	VBP
cord-257197-i9bucuma	59	12	easily	easily	RB
cord-257197-i9bucuma	59	13	controlled	control	VBN
cord-257197-i9bucuma	59	14	and	and	CC
cord-257197-i9bucuma	59	15	reproducible	reproducible	JJ
cord-257197-i9bucuma	59	16	,	,	,
cord-257197-i9bucuma	59	17	yet	yet	CC
cord-257197-i9bucuma	59	18	low	low	JJ
cord-257197-i9bucuma	59	19	in	in	IN
cord-257197-i9bucuma	59	20	cost	cost	NN
cord-257197-i9bucuma	59	21	and	and	CC
cord-257197-i9bucuma	59	22	scalable	scalable	JJ
cord-257197-i9bucuma	59	23	.	.	.
cord-257197-i9bucuma	60	1	40	40	CD
cord-257197-i9bucuma	60	2	Functionalization	Functionalization	NNP
cord-257197-i9bucuma	60	3	of	of	IN
cord-257197-i9bucuma	60	4	NPs	NPs	NNP
cord-257197-i9bucuma	60	5	has	have	VBZ
cord-257197-i9bucuma	60	6	proved	prove	VBN
cord-257197-i9bucuma	60	7	essential	essential	JJ
cord-257197-i9bucuma	60	8	as	as	IN
cord-257197-i9bucuma	60	9	they	-PRON-	PRP
cord-257197-i9bucuma	60	10	affect	affect	VBP
cord-257197-i9bucuma	60	11	stability	stability	NN
cord-257197-i9bucuma	60	12	in	in	IN
cord-257197-i9bucuma	60	13	the	the	DT
cord-257197-i9bucuma	60	14	presence	presence	NN
cord-257197-i9bucuma	60	15	of	of	IN
cord-257197-i9bucuma	60	16	salts	salt	NNS
cord-257197-i9bucuma	60	17	and	and	CC
cord-257197-i9bucuma	60	18	prevent	prevent	VB
cord-257197-i9bucuma	60	19	aggregation	aggregation	NN
cord-257197-i9bucuma	60	20	over	over	IN
cord-257197-i9bucuma	60	21	time	time	NN
cord-257197-i9bucuma	60	22	,	,	,
cord-257197-i9bucuma	60	23	thereby	thereby	RB
cord-257197-i9bucuma	60	24	increasing	increase	VBG
cord-257197-i9bucuma	60	25	their	-PRON-	PRP$
cord-257197-i9bucuma	60	26	shelf	shelf	NN
cord-257197-i9bucuma	60	27	-	-	HYPH
cord-257197-i9bucuma	60	28	life	life	NN
cord-257197-i9bucuma	60	29	.	.	.
cord-257197-i9bucuma	61	1	They	-PRON-	PRP
cord-257197-i9bucuma	61	2	may	may	MD
cord-257197-i9bucuma	61	3	also	also	RB
cord-257197-i9bucuma	61	4	have	have	VB
cord-257197-i9bucuma	61	5	other	other	JJ
cord-257197-i9bucuma	61	6	purposes	purpose	NNS
cord-257197-i9bucuma	61	7	including	include	VBG
cord-257197-i9bucuma	61	8	-	-	HYPH
cord-257197-i9bucuma	61	9	promoting	promote	VBG
cord-257197-i9bucuma	61	10	cellular	cellular	JJ
cord-257197-i9bucuma	61	11	uptake	uptake	NN
cord-257197-i9bucuma	61	12	,	,	,
cord-257197-i9bucuma	61	13	co	co	NN
cord-257197-i9bucuma	61	14	-	-	NN
cord-257197-i9bucuma	61	15	functionalization	functionalization	NN
cord-257197-i9bucuma	61	16	to	to	TO
cord-257197-i9bucuma	61	17	promote	promote	VB
cord-257197-i9bucuma	61	18	the	the	DT
cord-257197-i9bucuma	61	19	delivery	delivery	NN
cord-257197-i9bucuma	61	20	of	of	IN
cord-257197-i9bucuma	61	21	drugs	drug	NNS
cord-257197-i9bucuma	61	22	and	and	CC
cord-257197-i9bucuma	61	23	nucleic	nucleic	JJ
cord-257197-i9bucuma	61	24	acids	acid	NNS
cord-257197-i9bucuma	61	25	,	,	,
cord-257197-i9bucuma	61	26	use	use	VBP
cord-257197-i9bucuma	61	27	in	in	IN
cord-257197-i9bucuma	61	28	biochemical	biochemical	JJ
cord-257197-i9bucuma	61	29	assays	assay	NNS
cord-257197-i9bucuma	61	30	serving	serve	VBG
cord-257197-i9bucuma	61	31	as	as	IN
cord-257197-i9bucuma	61	32	binding	bind	VBG
cord-257197-i9bucuma	61	33	partners	partner	NNS
cord-257197-i9bucuma	61	34	,	,	,
cord-257197-i9bucuma	61	35	and	and	CC
cord-257197-i9bucuma	61	36	provide	provide	VB
cord-257197-i9bucuma	61	37	additional	additional	JJ
cord-257197-i9bucuma	61	38	functionalities	functionality	NNS
cord-257197-i9bucuma	61	39	to	to	IN
cord-257197-i9bucuma	61	40	the	the	DT
cord-257197-i9bucuma	61	41	delivery	delivery	NN
cord-257197-i9bucuma	61	42	system	system	NN
cord-257197-i9bucuma	61	43	.	.	.
cord-257197-i9bucuma	62	1	There	there	EX
cord-257197-i9bucuma	62	2	are	be	VBP
cord-257197-i9bucuma	62	3	a	a	DT
cord-257197-i9bucuma	62	4	wide	wide	JJ
cord-257197-i9bucuma	62	5	range	range	NN
cord-257197-i9bucuma	62	6	of	of	IN
cord-257197-i9bucuma	62	7	biocompatible	biocompatible	JJ
cord-257197-i9bucuma	62	8	molecules	molecule	NNS
cord-257197-i9bucuma	62	9	used	use	VBN
cord-257197-i9bucuma	62	10	to	to	TO
cord-257197-i9bucuma	62	11	functionalize	functionalize	VB
cord-257197-i9bucuma	62	12	the	the	DT
cord-257197-i9bucuma	62	13	NPs	NPs	NNPS
cord-257197-i9bucuma	62	14	for	for	IN
cord-257197-i9bucuma	62	15	use	use	NN
cord-257197-i9bucuma	62	16	in	in	IN
cord-257197-i9bucuma	62	17	nanomedicine	nanomedicine	NN
cord-257197-i9bucuma	62	18	which	which	WDT
cord-257197-i9bucuma	62	19	have	have	VBP
cord-257197-i9bucuma	62	20	been	be	VBN
cord-257197-i9bucuma	62	21	divided	divide	VBN
cord-257197-i9bucuma	62	22	into	into	IN
cord-257197-i9bucuma	62	23	5	5	CD
cord-257197-i9bucuma	62	24	major	major	JJ
cord-257197-i9bucuma	62	25	categories	category	NNS
cord-257197-i9bucuma	62	26	in	in	IN
cord-257197-i9bucuma	62	27	this	this	DT
cord-257197-i9bucuma	62	28	review	review	NN
cord-257197-i9bucuma	62	29	.	.	.
cord-257197-i9bucuma	63	1	(	(	-LRB-
cord-257197-i9bucuma	63	2	Ligand	Ligand	NNP
cord-257197-i9bucuma	63	3	exchange	exchange	NN
cord-257197-i9bucuma	63	4	by	by	IN
cord-257197-i9bucuma	63	5	direct	direct	JJ
cord-257197-i9bucuma	63	6	substitution	substitution	NN
cord-257197-i9bucuma	63	7	of	of	IN
cord-257197-i9bucuma	63	8	surface	surface	NN
cord-257197-i9bucuma	63	9	ligands	ligand	NNS
cord-257197-i9bucuma	63	10	is	be	VBZ
cord-257197-i9bucuma	63	11	one	one	CD
cord-257197-i9bucuma	63	12	of	of	IN
cord-257197-i9bucuma	63	13	the	the	DT
cord-257197-i9bucuma	63	14	commonly	commonly	RB
cord-257197-i9bucuma	63	15	used	use	VBN
cord-257197-i9bucuma	63	16	method	method	NN
cord-257197-i9bucuma	63	17	for	for	IN
cord-257197-i9bucuma	63	18	functionalizing	functionalize	VBG
cord-257197-i9bucuma	63	19	NPs	NPs	NNP
cord-257197-i9bucuma	63	20	.	.	.
cord-257197-i9bucuma	64	1	48	48	CD
cord-257197-i9bucuma	64	2	AuNPs	aunps	DT
cord-257197-i9bucuma	64	3	form	form	NN
cord-257197-i9bucuma	64	4	gold	gold	NN
cord-257197-i9bucuma	64	5	-	-	HYPH
cord-257197-i9bucuma	64	6	thiol	thiol	NN
cord-257197-i9bucuma	64	7	bonds	bond	NNS
cord-257197-i9bucuma	64	8	facilitating	facilitate	VBG
cord-257197-i9bucuma	64	9	exchange	exchange	NN
cord-257197-i9bucuma	64	10	of	of	IN
cord-257197-i9bucuma	64	11	smaller	small	JJR
cord-257197-i9bucuma	64	12	ligands	ligand	NNS
cord-257197-i9bucuma	64	13	such	such	JJ
cord-257197-i9bucuma	64	14	as	as	IN
cord-257197-i9bucuma	64	15	citrate	citrate	NN
cord-257197-i9bucuma	64	16	molecules	molecule	NNS
cord-257197-i9bucuma	64	17	with	with	IN
cord-257197-i9bucuma	64	18	larger	large	JJR
cord-257197-i9bucuma	64	19	molecules	molecule	NNS
cord-257197-i9bucuma	64	20	by	by	IN
cord-257197-i9bucuma	64	21	direct	direct	JJ
cord-257197-i9bucuma	64	22	binding	binding	NN
cord-257197-i9bucuma	64	23	of	of	IN
cord-257197-i9bucuma	64	24	ligands	ligand	NNS
cord-257197-i9bucuma	64	25	to	to	IN
cord-257197-i9bucuma	64	26	NPs	NPs	NNP
cord-257197-i9bucuma	64	27	via	via	IN
cord-257197-i9bucuma	64	28	Au	Au	NNP
cord-257197-i9bucuma	64	29	-	-	HYPH
cord-257197-i9bucuma	64	30	S	s	NN
cord-257197-i9bucuma	64	31	bond	bond	NN
cord-257197-i9bucuma	64	32	formation	formation	NN
cord-257197-i9bucuma	64	33	(	(	-LRB-
cord-257197-i9bucuma	64	34	Fig	Fig	NNP
cord-257197-i9bucuma	64	35	1C.	1c.	CD
cord-257197-i9bucuma	64	36	)	)	-RRB-
cord-257197-i9bucuma	64	37	.	.	.
cord-257197-i9bucuma	65	1	42	42	CD
cord-257197-i9bucuma	65	2	Biodegradable	biodegradable	JJ
cord-257197-i9bucuma	65	3	polymers	polymer	NNS
cord-257197-i9bucuma	65	4	are	be	VBP
cord-257197-i9bucuma	65	5	widely	widely	RB
cord-257197-i9bucuma	65	6	used	use	VBN
cord-257197-i9bucuma	65	7	as	as	IN
cord-257197-i9bucuma	65	8	surface	surface	NN
cord-257197-i9bucuma	65	9	coatings	coating	NNS
cord-257197-i9bucuma	65	10	,	,	,
cord-257197-i9bucuma	65	11	as	as	IN
cord-257197-i9bucuma	65	12	they	-PRON-	PRP
cord-257197-i9bucuma	65	13	are	be	VBP
cord-257197-i9bucuma	65	14	easy	easy	JJ
cord-257197-i9bucuma	65	15	to	to	TO
cord-257197-i9bucuma	65	16	synthesize	synthesize	VB
cord-257197-i9bucuma	65	17	,	,	,
cord-257197-i9bucuma	65	18	widely	widely	RB
cord-257197-i9bucuma	65	19	studied	study	VBN
cord-257197-i9bucuma	65	20	,	,	,
cord-257197-i9bucuma	65	21	allow	allow	VB
cord-257197-i9bucuma	65	22	for	for	IN
cord-257197-i9bucuma	65	23	precise	precise	JJ
cord-257197-i9bucuma	65	24	chemical	chemical	NN
cord-257197-i9bucuma	65	25	binding	binding	NN
cord-257197-i9bucuma	65	26	of	of	IN
cord-257197-i9bucuma	65	27	molecules	molecule	NNS
cord-257197-i9bucuma	65	28	or	or	CC
cord-257197-i9bucuma	65	29	can	can	MD
cord-257197-i9bucuma	65	30	be	be	VB
cord-257197-i9bucuma	65	31	modified	modify	VBN
cord-257197-i9bucuma	65	32	with	with	IN
cord-257197-i9bucuma	65	33	functional	functional	JJ
cord-257197-i9bucuma	65	34	groups	group	NNS
cord-257197-i9bucuma	65	35	to	to	TO
cord-257197-i9bucuma	65	36	bind	bind	VB
cord-257197-i9bucuma	65	37	other	other	JJ
cord-257197-i9bucuma	65	38	molecules	molecule	NNS
cord-257197-i9bucuma	65	39	using	use	VBG
cord-257197-i9bucuma	65	40	facile	facile	JJ
cord-257197-i9bucuma	65	41	chemistries	chemistry	NNS
cord-257197-i9bucuma	65	42	like	like	IN
cord-257197-i9bucuma	65	43	EDC	EDC	NNP
cord-257197-i9bucuma	65	44	-	-	HYPH
cord-257197-i9bucuma	65	45	NHS	NHS	NNP
cord-257197-i9bucuma	65	46	56	56	CD
cord-257197-i9bucuma	65	47	and	and	CC
cord-257197-i9bucuma	65	48	disulfide	disulfide	JJ
cord-257197-i9bucuma	65	49	conjugations	conjugation	NNS
cord-257197-i9bucuma	65	50	19	19	CD
cord-257197-i9bucuma	65	51	.	.	.
cord-257197-i9bucuma	66	1	They	-PRON-	PRP
cord-257197-i9bucuma	66	2	have	have	VBP
cord-257197-i9bucuma	66	3	been	be	VBN
cord-257197-i9bucuma	66	4	recognized	recognize	VBN
cord-257197-i9bucuma	66	5	to	to	TO
cord-257197-i9bucuma	66	6	increase	increase	VB
cord-257197-i9bucuma	66	7	the	the	DT
cord-257197-i9bucuma	66	8	circulation	circulation	NN
cord-257197-i9bucuma	66	9	time	time	NN
cord-257197-i9bucuma	66	10	of	of	IN
cord-257197-i9bucuma	66	11	the	the	DT
cord-257197-i9bucuma	66	12	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	66	13	by	by	IN
cord-257197-i9bucuma	66	14	preventing	prevent	VBG
cord-257197-i9bucuma	66	15	opsonization	opsonization	NN
cord-257197-i9bucuma	66	16	by	by	IN
cord-257197-i9bucuma	66	17	phagocytes	phagocyte	NNS
cord-257197-i9bucuma	66	18	in	in	IN
cord-257197-i9bucuma	66	19	vivo	vivo	NN
cord-257197-i9bucuma	66	20	.	.	.
cord-257197-i9bucuma	67	1	Therefore	therefore	RB
cord-257197-i9bucuma	67	2	,	,	,
cord-257197-i9bucuma	67	3	a	a	DT
cord-257197-i9bucuma	67	4	wide	wide	JJ
cord-257197-i9bucuma	67	5	range	range	NN
cord-257197-i9bucuma	67	6	of	of	IN
cord-257197-i9bucuma	67	7	FDA	FDA	NNP
cord-257197-i9bucuma	67	8	-	-	HYPH
cord-257197-i9bucuma	67	9	approved	approve	VBN
cord-257197-i9bucuma	67	10	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	67	11	and	and	CC
cord-257197-i9bucuma	67	12	in	in	IN
cord-257197-i9bucuma	67	13	vivo	vivo	NN
cord-257197-i9bucuma	67	14	devices	device	NNS
cord-257197-i9bucuma	67	15	are	be	VBP
cord-257197-i9bucuma	67	16	coated	coat	VBN
cord-257197-i9bucuma	67	17	with	with	IN
cord-257197-i9bucuma	67	18	one	one	CD
cord-257197-i9bucuma	67	19	or	or	CC
cord-257197-i9bucuma	67	20	more	more	JJR
cord-257197-i9bucuma	67	21	of	of	IN
cord-257197-i9bucuma	67	22	the	the	DT
cord-257197-i9bucuma	67	23	abovementioned	abovementioned	JJ
cord-257197-i9bucuma	67	24	polymers	polymer	NNS
cord-257197-i9bucuma	67	25	.	.	.
cord-257197-i9bucuma	68	1	57	57	CD
cord-257197-i9bucuma	69	1	A	a	DT
cord-257197-i9bucuma	69	2	recent	recent	JJ
cord-257197-i9bucuma	69	3	report	report	NN
cord-257197-i9bucuma	69	4	also	also	RB
cord-257197-i9bucuma	69	5	suggests	suggest	VBZ
cord-257197-i9bucuma	69	6	that	that	IN
cord-257197-i9bucuma	69	7	PEG	peg	NN
cord-257197-i9bucuma	69	8	-	-	HYPH
cord-257197-i9bucuma	69	9	like	like	JJ
cord-257197-i9bucuma	69	10	polymers	polymer	NNS
cord-257197-i9bucuma	69	11	may	may	MD
cord-257197-i9bucuma	69	12	not	not	RB
cord-257197-i9bucuma	69	13	be	be	VB
cord-257197-i9bucuma	69	14	as	as	RB
cord-257197-i9bucuma	69	15	inert	inert	JJ
cord-257197-i9bucuma	69	16	as	as	IN
cord-257197-i9bucuma	69	17	currently	currently	RB
cord-257197-i9bucuma	69	18	believed	believe	VBN
cord-257197-i9bucuma	69	19	.	.	.
cord-257197-i9bucuma	70	1	Their	-PRON-	PRP$
cord-257197-i9bucuma	70	2	oxidative	oxidative	JJ
cord-257197-i9bucuma	70	3	degradation	degradation	NN
cord-257197-i9bucuma	70	4	in	in	IN
cord-257197-i9bucuma	70	5	vivo	vivo	NN
cord-257197-i9bucuma	70	6	can	can	MD
cord-257197-i9bucuma	70	7	lead	lead	VB
cord-257197-i9bucuma	70	8	to	to	IN
cord-257197-i9bucuma	70	9	detrimental	detrimental	JJ
cord-257197-i9bucuma	70	10	effects	effect	NNS
cord-257197-i9bucuma	70	11	on	on	IN
cord-257197-i9bucuma	70	12	the	the	DT
cord-257197-i9bucuma	70	13	cell	cell	NN
cord-257197-i9bucuma	70	14	membrane	membrane	NN
cord-257197-i9bucuma	70	15	and	and	CC
cord-257197-i9bucuma	70	16	affect	affect	VB
cord-257197-i9bucuma	70	17	signal	signal	NN
cord-257197-i9bucuma	70	18	transduction	transduction	NN
cord-257197-i9bucuma	70	19	pathways	pathway	NNS
cord-257197-i9bucuma	70	20	.	.	.
cord-257197-i9bucuma	71	1	58	58	CD
cord-257197-i9bucuma	72	1	Therefore	therefore	RB
cord-257197-i9bucuma	72	2	,	,	,
cord-257197-i9bucuma	72	3	recent	recent	JJ
cord-257197-i9bucuma	72	4	emphasis	emphasis	NN
cord-257197-i9bucuma	72	5	has	have	VBZ
cord-257197-i9bucuma	72	6	been	be	VBN
cord-257197-i9bucuma	72	7	on	on	IN
cord-257197-i9bucuma	72	8	J	J	NNP
cord-257197-i9bucuma	72	9	o	o	NN
cord-257197-i9bucuma	72	10	u	u	NN
cord-257197-i9bucuma	72	11	r	r	NN
cord-257197-i9bucuma	72	12	n	n	NN
cord-257197-i9bucuma	72	13	a	a	DT
cord-257197-i9bucuma	72	14	l	l	NN
cord-257197-i9bucuma	72	15	P	p	NN
cord-257197-i9bucuma	72	16	r	r	NN
cord-257197-i9bucuma	72	17	e	e	NN
cord-257197-i9bucuma	72	18	-p	-p	NN
cord-257197-i9bucuma	73	1	r	r	NN
cord-257197-i9bucuma	73	2	o	o	NN
cord-257197-i9bucuma	73	3	o	o	NN
cord-257197-i9bucuma	73	4	f	f	NFP
cord-257197-i9bucuma	73	5	the	the	DT
cord-257197-i9bucuma	73	6	use	use	NN
cord-257197-i9bucuma	73	7	of	of	IN
cord-257197-i9bucuma	73	8	natural	natural	JJ
cord-257197-i9bucuma	73	9	or	or	CC
cord-257197-i9bucuma	73	10	synthetic	synthetic	JJ
cord-257197-i9bucuma	73	11	biocompatible	biocompatible	JJ
cord-257197-i9bucuma	73	12	surface	surface	NN
cord-257197-i9bucuma	73	13	coatings	coating	NNS
cord-257197-i9bucuma	73	14	which	which	WDT
cord-257197-i9bucuma	73	15	display	display	VBP
cord-257197-i9bucuma	73	16	minimal	minimal	JJ
cord-257197-i9bucuma	73	17	adverse	adverse	JJ
cord-257197-i9bucuma	73	18	effects	effect	NNS
cord-257197-i9bucuma	73	19	.	.	.
cord-257197-i9bucuma	74	1	Lipid	lipid	NN
cord-257197-i9bucuma	74	2	amphiphiles	amphiphile	NNS
cord-257197-i9bucuma	74	3	comprised	comprise	VBN
cord-257197-i9bucuma	74	4	of	of	IN
cord-257197-i9bucuma	74	5	one	one	CD
cord-257197-i9bucuma	74	6	acyl	acyl	NN
cord-257197-i9bucuma	74	7	chain	chain	NN
cord-257197-i9bucuma	74	8	generally	generally	RB
cord-257197-i9bucuma	74	9	form	form	VBP
cord-257197-i9bucuma	74	10	micelles	micelle	NNS
cord-257197-i9bucuma	74	11	while	while	IN
cord-257197-i9bucuma	74	12	those	those	DT
cord-257197-i9bucuma	74	13	with	with	IN
cord-257197-i9bucuma	74	14	two	two	CD
cord-257197-i9bucuma	74	15	acyl	acyl	NN
cord-257197-i9bucuma	74	16	chains	chain	NNS
cord-257197-i9bucuma	74	17	assemble	assemble	VBP
cord-257197-i9bucuma	74	18	into	into	IN
cord-257197-i9bucuma	74	19	bilayer	bilayer	NN
cord-257197-i9bucuma	74	20	-	-	HYPH
cord-257197-i9bucuma	74	21	like	like	JJ
cord-257197-i9bucuma	74	22	membrane	membrane	NN
cord-257197-i9bucuma	74	23	vesicles	vesicle	NNS
cord-257197-i9bucuma	74	24	called	call	VBN
cord-257197-i9bucuma	74	25	liposomes	liposome	NNS
cord-257197-i9bucuma	74	26	.	.	.
cord-257197-i9bucuma	75	1	Commonly	commonly	RB
cord-257197-i9bucuma	75	2	,	,	,
cord-257197-i9bucuma	75	3	lipid	lipid	NN
cord-257197-i9bucuma	75	4	formulations	formulation	NNS
cord-257197-i9bucuma	75	5	yield	yield	VBP
cord-257197-i9bucuma	75	6	self	self	NN
cord-257197-i9bucuma	75	7	-	-	HYPH
cord-257197-i9bucuma	75	8	assembled	assemble	VBN
cord-257197-i9bucuma	75	9	structures	structure	NNS
cord-257197-i9bucuma	75	10	that	that	WDT
cord-257197-i9bucuma	75	11	are	be	VBP
cord-257197-i9bucuma	75	12	greater	great	JJR
cord-257197-i9bucuma	75	13	than	than	IN
cord-257197-i9bucuma	75	14	100	100	CD
cord-257197-i9bucuma	75	15	nm	nm	NN
cord-257197-i9bucuma	75	16	.	.	.
cord-257197-i9bucuma	76	1	The	the	DT
cord-257197-i9bucuma	76	2	first	first	JJ
cord-257197-i9bucuma	76	3	liposomal	liposomal	JJ
cord-257197-i9bucuma	76	4	formulation	formulation	NN
cord-257197-i9bucuma	76	5	to	to	TO
cord-257197-i9bucuma	76	6	be	be	VB
cord-257197-i9bucuma	76	7	approved	approve	VBN
cord-257197-i9bucuma	76	8	by	by	IN
cord-257197-i9bucuma	76	9	the	the	DT
cord-257197-i9bucuma	76	10	FDA	FDA	NNP
cord-257197-i9bucuma	76	11	was	be	VBD
cord-257197-i9bucuma	76	12	Doxil	Doxil	NNP
cord-257197-i9bucuma	76	13	in	in	IN
cord-257197-i9bucuma	76	14	1995	1995	CD
cord-257197-i9bucuma	76	15	,	,	,
cord-257197-i9bucuma	76	16	subsequently	subsequently	RB
cord-257197-i9bucuma	76	17	9	9	CD
cord-257197-i9bucuma	76	18	additional	additional	JJ
cord-257197-i9bucuma	76	19	liposomal	liposomal	JJ
cord-257197-i9bucuma	76	20	formulations	formulation	NNS
cord-257197-i9bucuma	76	21	with	with	IN
cord-257197-i9bucuma	76	22	active	active	JJ
cord-257197-i9bucuma	76	23	ingredients	ingredient	NNS
cord-257197-i9bucuma	76	24	(	(	-LRB-
cord-257197-i9bucuma	76	25	AIs	AIs	NNP
cord-257197-i9bucuma	76	26	)	)	-RRB-
cord-257197-i9bucuma	76	27	have	have	VBP
cord-257197-i9bucuma	76	28	been	be	VBN
cord-257197-i9bucuma	76	29	approved	approve	VBN
cord-257197-i9bucuma	76	30	.	.	.
cord-257197-i9bucuma	77	1	59	59	CD
cord-257197-i9bucuma	77	2	Single	single	JJ
cord-257197-i9bucuma	77	3	chained	chained	JJ
cord-257197-i9bucuma	77	4	lipid	lipid	NN
cord-257197-i9bucuma	77	5	amphiphiles	amphiphile	NNS
cord-257197-i9bucuma	77	6	such	such	JJ
cord-257197-i9bucuma	77	7	as	as	IN
cord-257197-i9bucuma	77	8	lysophosphatidylcholine	lysophosphatidylcholine	NNP
cord-257197-i9bucuma	77	9	and	and	CC
cord-257197-i9bucuma	77	10	two	two	CD
cord-257197-i9bucuma	77	11	-	-	HYPH
cord-257197-i9bucuma	77	12	chained	chain	VBN
cord-257197-i9bucuma	77	13	DOPC	DOPC	NNP
cord-257197-i9bucuma	77	14	,	,	,
cord-257197-i9bucuma	77	15	POPC	POPC	NNP
cord-257197-i9bucuma	77	16	60	60	CD
cord-257197-i9bucuma	77	17	,	,	,
cord-257197-i9bucuma	77	18	as	as	RB
cord-257197-i9bucuma	77	19	well	well	RB
cord-257197-i9bucuma	77	20	as	as	IN
cord-257197-i9bucuma	77	21	cholesterol	cholesterol	NN
cord-257197-i9bucuma	77	22	and/or	and/or	CC
cord-257197-i9bucuma	77	23	their	-PRON-	PRP$
cord-257197-i9bucuma	77	24	mixtures	mixture	NNS
cord-257197-i9bucuma	77	25	have	have	VBP
cord-257197-i9bucuma	77	26	been	be	VBN
cord-257197-i9bucuma	77	27	incorporated	incorporate	VBN
cord-257197-i9bucuma	77	28	into	into	IN
cord-257197-i9bucuma	77	29	liposomes	liposome	NNS
cord-257197-i9bucuma	77	30	3	3	CD
cord-257197-i9bucuma	77	31	,	,	,
cord-257197-i9bucuma	77	32	polymeric	polymeric	JJ
cord-257197-i9bucuma	77	33	liposomes	liposome	NNS
cord-257197-i9bucuma	77	34	6	6	CD
cord-257197-i9bucuma	77	35	(	(	-LRB-
cord-257197-i9bucuma	77	36	polymer	polymer	NN
cord-257197-i9bucuma	77	37	modified	modify	VBN
cord-257197-i9bucuma	77	38	lipid	lipid	NN
cord-257197-i9bucuma	77	39	components	component	NNS
cord-257197-i9bucuma	77	40	)	)	-RRB-
cord-257197-i9bucuma	77	41	and	and	CC
cord-257197-i9bucuma	77	42	to	to	IN
cord-257197-i9bucuma	77	43	functionalize	functionalize	NNP
cord-257197-i9bucuma	77	44	inorganic	inorganic	NNP
cord-257197-i9bucuma	77	45	core	core	NNP
cord-257197-i9bucuma	77	46	NPs	NPs	NNP
cord-257197-i9bucuma	77	47	.	.	.
cord-257197-i9bucuma	78	1	A	a	DT
cord-257197-i9bucuma	78	2	reverse	reverse	JJ
cord-257197-i9bucuma	78	3	phase	phase	NN
cord-257197-i9bucuma	78	4	evaporation	evaporation	NN
cord-257197-i9bucuma	78	5	method	method	NN
cord-257197-i9bucuma	78	6	that	that	WDT
cord-257197-i9bucuma	78	7	involves	involve	VBZ
cord-257197-i9bucuma	78	8	exchanging	exchange	VBG
cord-257197-i9bucuma	78	9	the	the	DT
cord-257197-i9bucuma	78	10	existing	exist	VBG
cord-257197-i9bucuma	78	11	surface	surface	NN
cord-257197-i9bucuma	78	12	ligands	ligand	NNS
cord-257197-i9bucuma	78	13	with	with	IN
cord-257197-i9bucuma	78	14	lipids	lipid	NNS
cord-257197-i9bucuma	78	15	in	in	IN
cord-257197-i9bucuma	78	16	an	an	DT
cord-257197-i9bucuma	78	17	organic	organic	JJ
cord-257197-i9bucuma	78	18	solvent	solvent	NN
cord-257197-i9bucuma	78	19	followed	follow	VBN
cord-257197-i9bucuma	78	20	by	by	IN
cord-257197-i9bucuma	78	21	transfer	transfer	NN
cord-257197-i9bucuma	78	22	to	to	IN
cord-257197-i9bucuma	78	23	an	an	DT
cord-257197-i9bucuma	78	24	aqueous	aqueous	JJ
cord-257197-i9bucuma	78	25	solvent	solvent	NN
cord-257197-i9bucuma	78	26	,	,	,
cord-257197-i9bucuma	78	27	is	be	VBZ
cord-257197-i9bucuma	78	28	commonly	commonly	RB
cord-257197-i9bucuma	78	29	used	use	VBN
cord-257197-i9bucuma	78	30	for	for	IN
cord-257197-i9bucuma	78	31	lipid	lipid	NN
cord-257197-i9bucuma	78	32	membrane	membrane	NN
cord-257197-i9bucuma	78	33	assembly	assembly	NN
cord-257197-i9bucuma	78	34	on	on	IN
cord-257197-i9bucuma	78	35	NPs	NPs	NNP
cord-257197-i9bucuma	78	36	.	.	.
cord-257197-i9bucuma	79	1	This	this	DT
cord-257197-i9bucuma	79	2	technique	technique	NN
cord-257197-i9bucuma	79	3	has	have	VBZ
cord-257197-i9bucuma	79	4	been	be	VBN
cord-257197-i9bucuma	79	5	employed	employ	VBN
cord-257197-i9bucuma	79	6	in	in	IN
cord-257197-i9bucuma	79	7	the	the	DT
cord-257197-i9bucuma	79	8	synthesis	synthesis	NN
cord-257197-i9bucuma	79	9	of	of	IN
cord-257197-i9bucuma	79	10	hybrid	hybrid	JJ
cord-257197-i9bucuma	79	11	lipid	lipid	NN
cord-257197-i9bucuma	79	12	bilayer	bilayer	NN
cord-257197-i9bucuma	79	13	coatings	coating	NNS
cord-257197-i9bucuma	79	14	on	on	IN
cord-257197-i9bucuma	79	15	NPs	NPs	NNP
cord-257197-i9bucuma	79	16	where	where	WRB
cord-257197-i9bucuma	79	17	inner	inner	JJ
cord-257197-i9bucuma	79	18	and	and	CC
cord-257197-i9bucuma	79	19	outer	outer	JJ
cord-257197-i9bucuma	79	20	layer	layer	NN
cord-257197-i9bucuma	79	21	have	have	VBP
cord-257197-i9bucuma	79	22	different	different	JJ
cord-257197-i9bucuma	79	23	compositions	composition	NNS
cord-257197-i9bucuma	79	24	.	.	.
cord-257197-i9bucuma	80	1	6	6	CD
cord-257197-i9bucuma	80	2	,	,	,
cord-257197-i9bucuma	80	3	60	60	CD
cord-257197-i9bucuma	81	1	Another	another	DT
cord-257197-i9bucuma	81	2	common	common	JJ
cord-257197-i9bucuma	81	3	technique	technique	NN
cord-257197-i9bucuma	81	4	involves	involve	VBZ
cord-257197-i9bucuma	81	5	adsorption	adsorption	NN
cord-257197-i9bucuma	81	6	of	of	IN
cord-257197-i9bucuma	81	7	liposomes	liposome	NNS
cord-257197-i9bucuma	81	8	4	4	CD
cord-257197-i9bucuma	81	9	,	,	,
cord-257197-i9bucuma	81	10	on	on	IN
cord-257197-i9bucuma	81	11	the	the	DT
cord-257197-i9bucuma	81	12	NPs	NPs	NNPS
cord-257197-i9bucuma	81	13	where	where	WRB
cord-257197-i9bucuma	81	14	the	the	DT
cord-257197-i9bucuma	81	15	charged	charge	VBN
cord-257197-i9bucuma	81	16	head	head	NN
cord-257197-i9bucuma	81	17	moieties	moiety	NNS
cord-257197-i9bucuma	81	18	interact	interact	VBP
cord-257197-i9bucuma	81	19	with	with	IN
cord-257197-i9bucuma	81	20	the	the	DT
cord-257197-i9bucuma	81	21	surface	surface	NN
cord-257197-i9bucuma	81	22	and	and	CC
cord-257197-i9bucuma	81	23	encapsulate	encapsulate	VB
cord-257197-i9bucuma	81	24	the	the	DT
cord-257197-i9bucuma	81	25	NPs	NPs	NNPS
cord-257197-i9bucuma	81	26	within	within	IN
cord-257197-i9bucuma	81	27	liposomes	liposome	NNS
cord-257197-i9bucuma	81	28	.	.	.
cord-257197-i9bucuma	82	1	5	5	LS
cord-257197-i9bucuma	83	1	However	however	RB
cord-257197-i9bucuma	83	2	,	,	,
cord-257197-i9bucuma	83	3	lipid	lipid	NN
cord-257197-i9bucuma	83	4	membranes	membrane	NNS
cord-257197-i9bucuma	83	5	often	often	RB
cord-257197-i9bucuma	83	6	have	have	VBP
cord-257197-i9bucuma	83	7	low	low	JJ
cord-257197-i9bucuma	83	8	stability	stability	NN
cord-257197-i9bucuma	83	9	in	in	IN
cord-257197-i9bucuma	83	10	solution	solution	NN
cord-257197-i9bucuma	83	11	due	due	IN
cord-257197-i9bucuma	83	12	to	to	IN
cord-257197-i9bucuma	83	13	fusion	fusion	NN
cord-257197-i9bucuma	83	14	,	,	,
cord-257197-i9bucuma	83	15	leading	lead	VBG
cord-257197-i9bucuma	83	16	to	to	IN
cord-257197-i9bucuma	83	17	increases	increase	NNS
cord-257197-i9bucuma	83	18	in	in	IN
cord-257197-i9bucuma	83	19	the	the	DT
cord-257197-i9bucuma	83	20	particle	particle	NN
cord-257197-i9bucuma	83	21	size	size	NN
cord-257197-i9bucuma	83	22	.	.	.
cord-257197-i9bucuma	84	1	61	61	CD
cord-257197-i9bucuma	85	1	This	this	DT
cord-257197-i9bucuma	85	2	can	can	MD
cord-257197-i9bucuma	85	3	be	be	VB
cord-257197-i9bucuma	85	4	remedied	remedie	VBN
cord-257197-i9bucuma	85	5	by	by	IN
cord-257197-i9bucuma	85	6	increasing	increase	VBG
cord-257197-i9bucuma	85	7	the	the	DT
cord-257197-i9bucuma	85	8	surface	surface	NN
cord-257197-i9bucuma	85	9	charges	charge	NNS
cord-257197-i9bucuma	85	10	that	that	WDT
cord-257197-i9bucuma	85	11	promote	promote	VBP
cord-257197-i9bucuma	85	12	repulsion	repulsion	NN
cord-257197-i9bucuma	85	13	between	between	IN
cord-257197-i9bucuma	85	14	particles	particle	NNS
cord-257197-i9bucuma	85	15	or	or	CC
cord-257197-i9bucuma	85	16	by	by	IN
cord-257197-i9bucuma	85	17	incorporating	incorporate	VBG
cord-257197-i9bucuma	85	18	spacers	spacer	NNS
cord-257197-i9bucuma	85	19	such	such	JJ
cord-257197-i9bucuma	85	20	as	as	IN
cord-257197-i9bucuma	85	21	PEG	PEG	NNP
cord-257197-i9bucuma	85	22	that	that	IN
cord-257197-i9bucuma	85	23	sterically	sterically	RB
cord-257197-i9bucuma	85	24	hinder	hinder	VBP
cord-257197-i9bucuma	85	25	particle	particle	NN
cord-257197-i9bucuma	85	26	association	association	NN
cord-257197-i9bucuma	85	27	.	.	.
cord-257197-i9bucuma	86	1	These	these	DT
cord-257197-i9bucuma	86	2	methods	method	NNS
cord-257197-i9bucuma	86	3	improve	improve	VBP
cord-257197-i9bucuma	86	4	colloidal	colloidal	NN
cord-257197-i9bucuma	86	5	stability	stability	NN
cord-257197-i9bucuma	86	6	.	.	.
cord-257197-i9bucuma	87	1	utilized	utilize	VBN
cord-257197-i9bucuma	87	2	to	to	IN
cord-257197-i9bucuma	87	3	functionalize	functionalize	NNP
cord-257197-i9bucuma	87	4	NPs	NPs	NNP
cord-257197-i9bucuma	87	5	with	with	IN
cord-257197-i9bucuma	87	6	peptides	peptide	NNS
cord-257197-i9bucuma	87	7	(	(	-LRB-
cord-257197-i9bucuma	87	8	Fig	Fig	NNP
cord-257197-i9bucuma	87	9	1C.	1c.	CD
cord-257197-i9bucuma	87	10	)	)	-RRB-
cord-257197-i9bucuma	87	11	.	.	.
cord-257197-i9bucuma	88	1	Although	although	IN
cord-257197-i9bucuma	88	2	amines	amine	NNS
cord-257197-i9bucuma	88	3	bind	bind	VBP
cord-257197-i9bucuma	88	4	to	to	IN
cord-257197-i9bucuma	88	5	the	the	DT
cord-257197-i9bucuma	88	6	gold	gold	NN
cord-257197-i9bucuma	88	7	surfaces	surface	NNS
cord-257197-i9bucuma	88	8	,	,	,
cord-257197-i9bucuma	88	9	the	the	DT
cord-257197-i9bucuma	88	10	strength	strength	NN
cord-257197-i9bucuma	88	11	of	of	IN
cord-257197-i9bucuma	88	12	Au	Au	NNP
cord-257197-i9bucuma	88	13	-	-	HYPH
cord-257197-i9bucuma	88	14	N	N	NNP
cord-257197-i9bucuma	88	15	(	(	-LRB-
cord-257197-i9bucuma	88	16	~4	~4	NFP
cord-257197-i9bucuma	88	17	kJ	kJ	NNP
cord-257197-i9bucuma	88	18	/	/	SYM
cord-257197-i9bucuma	88	19	mol	mol	NN
cord-257197-i9bucuma	88	20	)	)	-RRB-
cord-257197-i9bucuma	88	21	bond	bond	NN
cord-257197-i9bucuma	88	22	is	be	VBZ
cord-257197-i9bucuma	88	23	much	much	RB
cord-257197-i9bucuma	88	24	weaker	weak	JJR
cord-257197-i9bucuma	88	25	than	than	IN
cord-257197-i9bucuma	88	26	the	the	DT
cord-257197-i9bucuma	88	27	Au	Au	NNP
cord-257197-i9bucuma	88	28	-	-	HYPH
cord-257197-i9bucuma	88	29	thiol	thiol	NN
cord-257197-i9bucuma	88	30	bond	bond	NN
cord-257197-i9bucuma	88	31	(	(	-LRB-
cord-257197-i9bucuma	88	32	137	137	CD
cord-257197-i9bucuma	88	33	kJ	kJ	NNP
cord-257197-i9bucuma	88	34	/	/	SYM
cord-257197-i9bucuma	88	35	mol	mol	NN
cord-257197-i9bucuma	88	36	)	)	-RRB-
cord-257197-i9bucuma	88	37	that	that	WDT
cord-257197-i9bucuma	88	38	is	be	VBZ
cord-257197-i9bucuma	88	39	commonly	commonly	RB
cord-257197-i9bucuma	88	40	used	use	VBN
cord-257197-i9bucuma	88	41	to	to	TO
cord-257197-i9bucuma	88	42	bind	bind	VB
cord-257197-i9bucuma	88	43	cysteine	cysteine	NN
cord-257197-i9bucuma	88	44	containing	contain	VBG
cord-257197-i9bucuma	88	45	peptides	peptide	NNS
cord-257197-i9bucuma	88	46	under	under	IN
cord-257197-i9bucuma	88	47	appropriate	appropriate	JJ
cord-257197-i9bucuma	88	48	conditions	condition	NNS
cord-257197-i9bucuma	88	49	.	.	.
cord-257197-i9bucuma	89	1	49	49	CD
cord-257197-i9bucuma	89	2	,	,	,
cord-257197-i9bucuma	89	3	55	55	CD
cord-257197-i9bucuma	90	1	,	,	,
cord-257197-i9bucuma	90	2	62	62	CD
cord-257197-i9bucuma	90	3	Cell	cell	NN
cord-257197-i9bucuma	90	4	penetrating	penetrating	JJ
cord-257197-i9bucuma	90	5	peptides	peptide	NNS
cord-257197-i9bucuma	90	6	like	like	IN
cord-257197-i9bucuma	90	7	HIV-1	HIV-1	NNP
cord-257197-i9bucuma	90	8	derived	derive	VBD
cord-257197-i9bucuma	90	9	TAT	TAT	NNP
cord-257197-i9bucuma	90	10	peptide	peptide	NN
cord-257197-i9bucuma	90	11	63	63	CD
cord-257197-i9bucuma	90	12	promote	promote	VBP
cord-257197-i9bucuma	90	13	the	the	DT
cord-257197-i9bucuma	90	14	uptake	uptake	NN
cord-257197-i9bucuma	90	15	of	of	IN
cord-257197-i9bucuma	90	16	molecules	molecule	NNS
cord-257197-i9bucuma	90	17	or	or	CC
cord-257197-i9bucuma	90	18	complexes	complex	NNS
cord-257197-i9bucuma	90	19	that	that	WDT
cord-257197-i9bucuma	90	20	can	can	MD
cord-257197-i9bucuma	90	21	not	not	RB
cord-257197-i9bucuma	90	22	penetrate	penetrate	VB
cord-257197-i9bucuma	90	23	the	the	DT
cord-257197-i9bucuma	90	24	cell	cell	NN
cord-257197-i9bucuma	90	25	membrane	membrane	NN
cord-257197-i9bucuma	90	26	efficiently	efficiently	RB
cord-257197-i9bucuma	90	27	by	by	IN
cord-257197-i9bucuma	90	28	themselves	-PRON-	PRP
cord-257197-i9bucuma	90	29	.	.	.
cord-257197-i9bucuma	91	1	They	-PRON-	PRP
cord-257197-i9bucuma	91	2	are	be	VBP
cord-257197-i9bucuma	91	3	therefore	therefore	RB
cord-257197-i9bucuma	91	4	used	use	VBN
cord-257197-i9bucuma	91	5	to	to	TO
cord-257197-i9bucuma	91	6	co	co	VB
cord-257197-i9bucuma	91	7	-	-	VB
cord-257197-i9bucuma	91	8	functionalize	functionalize	VB
cord-257197-i9bucuma	91	9	the	the	DT
cord-257197-i9bucuma	91	10	surface	surface	NN
cord-257197-i9bucuma	91	11	of	of	IN
cord-257197-i9bucuma	91	12	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	91	13	and	and	CC
cord-257197-i9bucuma	91	14	are	be	VBP
cord-257197-i9bucuma	91	15	widely	widely	RB
cord-257197-i9bucuma	91	16	explored	explore	VBN
cord-257197-i9bucuma	91	17	for	for	IN
cord-257197-i9bucuma	91	18	delivery	delivery	NN
cord-257197-i9bucuma	91	19	of	of	IN
cord-257197-i9bucuma	91	20	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	91	21	in	in	IN
cord-257197-i9bucuma	91	22	radiation	radiation	NN
cord-257197-i9bucuma	91	23	therapy	therapy	NN
cord-257197-i9bucuma	91	24	63	63	CD
cord-257197-i9bucuma	91	25	 	 	_SP
cord-257197-i9bucuma	91	26	Specific	specific	JJ
cord-257197-i9bucuma	91	27	proteins	protein	NNS
cord-257197-i9bucuma	91	28	can	can	MD
cord-257197-i9bucuma	91	29	be	be	VB
cord-257197-i9bucuma	91	30	used	use	VBN
cord-257197-i9bucuma	91	31	to	to	IN
cord-257197-i9bucuma	91	32	functionalize	functionalize	NNP
cord-257197-i9bucuma	91	33	NPs	NPs	NNP
cord-257197-i9bucuma	91	34	for	for	IN
cord-257197-i9bucuma	91	35	targeted	target	VBN
cord-257197-i9bucuma	91	36	delivery	delivery	NN
cord-257197-i9bucuma	91	37	or	or	CC
cord-257197-i9bucuma	91	38	to	to	TO
cord-257197-i9bucuma	91	39	serve	serve	VB
cord-257197-i9bucuma	91	40	as	as	IN
cord-257197-i9bucuma	91	41	binding	bind	VBG
cord-257197-i9bucuma	91	42	partners	partner	NNS
cord-257197-i9bucuma	91	43	in	in	IN
cord-257197-i9bucuma	91	44	assays	assay	NNS
cord-257197-i9bucuma	91	45	.	.	.
cord-257197-i9bucuma	92	1	Abraxane	Abraxane	NNP
cord-257197-i9bucuma	92	2	®	®	NNP
cord-257197-i9bucuma	92	3	is	be	VBZ
cord-257197-i9bucuma	92	4	an	an	DT
cord-257197-i9bucuma	92	5	FDA	FDA	NNP
cord-257197-i9bucuma	92	6	-	-	HYPH
cord-257197-i9bucuma	92	7	approved	approve	VBN
cord-257197-i9bucuma	92	8	chemotherapeutic	chemotherapeutic	JJ
cord-257197-i9bucuma	92	9	drug	drug	NN
cord-257197-i9bucuma	92	10	that	that	WDT
cord-257197-i9bucuma	92	11	consists	consist	VBZ
cord-257197-i9bucuma	92	12	of	of	IN
cord-257197-i9bucuma	92	13	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	92	14	albumin	albumin	NN
cord-257197-i9bucuma	92	15	bound	bind	VBN
cord-257197-i9bucuma	92	16	(	(	-LRB-
cord-257197-i9bucuma	92	17	nab)-paclitaxel	nab)-paclitaxel	XX
cord-257197-i9bucuma	92	18	.	.	.
cord-257197-i9bucuma	93	1	Albumin	albumin	NN
cord-257197-i9bucuma	93	2	is	be	VBZ
cord-257197-i9bucuma	93	3	an	an	DT
cord-257197-i9bucuma	93	4	abundant	abundant	JJ
cord-257197-i9bucuma	93	5	serum	serum	NN
cord-257197-i9bucuma	93	6	protein	protein	NN
cord-257197-i9bucuma	93	7	used	use	VBN
cord-257197-i9bucuma	93	8	as	as	IN
cord-257197-i9bucuma	93	9	surface	surface	NN
cord-257197-i9bucuma	93	10	coating	coating	NN
cord-257197-i9bucuma	93	11	for	for	IN
cord-257197-i9bucuma	93	12	NPs	NPs	NNPS
cord-257197-i9bucuma	93	13	as	as	IN
cord-257197-i9bucuma	93	14	it	-PRON-	PRP
cord-257197-i9bucuma	93	15	improves	improve	VBZ
cord-257197-i9bucuma	93	16	bioavailability	bioavailability	NN
cord-257197-i9bucuma	93	17	,	,	,
cord-257197-i9bucuma	93	18	has	have	VBZ
cord-257197-i9bucuma	93	19	low	low	JJ
cord-257197-i9bucuma	93	20	immunogenicity	immunogenicity	NN
cord-257197-i9bucuma	93	21	and	and	CC
cord-257197-i9bucuma	93	22	good	good	JJ
cord-257197-i9bucuma	93	23	biocompatibility	biocompatibility	NN
cord-257197-i9bucuma	93	24	.	.	.
cord-257197-i9bucuma	94	1	72	72	CD
cord-257197-i9bucuma	94	2	,	,	,
cord-257197-i9bucuma	94	3	73	73	CD
cord-257197-i9bucuma	94	4	Nab	Nab	NNP
cord-257197-i9bucuma	94	5	-	-	HYPH
cord-257197-i9bucuma	94	6	paclitaxel	paclitaxel	NNS
cord-257197-i9bucuma	94	7	and	and	CC
cord-257197-i9bucuma	94	8	its	-PRON-	PRP$
cord-257197-i9bucuma	94	9	variations	variation	NNS
cord-257197-i9bucuma	94	10	comprise	comprise	VBP
cord-257197-i9bucuma	94	11	a	a	DT
cord-257197-i9bucuma	94	12	major	major	JJ
cord-257197-i9bucuma	94	13	percentage	percentage	NN
cord-257197-i9bucuma	94	14	of	of	IN
cord-257197-i9bucuma	94	15	the	the	DT
cord-257197-i9bucuma	94	16	protein	protein	NN
cord-257197-i9bucuma	94	17	based	base	VBN
cord-257197-i9bucuma	94	18	nanomedicines	nanomedicine	NNS
cord-257197-i9bucuma	94	19	in	in	IN
cord-257197-i9bucuma	94	20	clinical	clinical	JJ
cord-257197-i9bucuma	94	21	trials	trial	NNS
cord-257197-i9bucuma	95	1	(	(	-LRB-
cord-257197-i9bucuma	95	2	Fig	Fig	NNP
cord-257197-i9bucuma	95	3	.	.	.
cord-257197-i9bucuma	95	4	1D	1d	CD
cord-257197-i9bucuma	95	5	)	)	-RRB-
cord-257197-i9bucuma	95	6	.	.	.
cord-257197-i9bucuma	96	1	This	this	DT
cord-257197-i9bucuma	96	2	success	success	NN
cord-257197-i9bucuma	96	3	has	have	VBZ
cord-257197-i9bucuma	96	4	fostered	foster	VBN
cord-257197-i9bucuma	96	5	the	the	DT
cord-257197-i9bucuma	96	6	use	use	NN
cord-257197-i9bucuma	96	7	of	of	IN
cord-257197-i9bucuma	96	8	albumin	albumin	NN
cord-257197-i9bucuma	96	9	as	as	IN
cord-257197-i9bucuma	96	10	a	a	DT
cord-257197-i9bucuma	96	11	surface	surface	NN
cord-257197-i9bucuma	96	12	coating	coating	NN
cord-257197-i9bucuma	96	13	for	for	IN
cord-257197-i9bucuma	96	14	additional	additional	JJ
cord-257197-i9bucuma	96	15	NPs	NPs	NNP
cord-257197-i9bucuma	96	16	delivery	delivery	NN
cord-257197-i9bucuma	96	17	systems	system	NNS
cord-257197-i9bucuma	96	18	.	.	.
cord-257197-i9bucuma	97	1	[	[	-LRB-
cord-257197-i9bucuma	97	2	74	74	CD
cord-257197-i9bucuma	97	3	]	]	-RRB-
cord-257197-i9bucuma	97	4	[	[	-LRB-
cord-257197-i9bucuma	97	5	75	75	CD
cord-257197-i9bucuma	97	6	]	]	-RRB-
cord-257197-i9bucuma	97	7	[	[	-LRB-
cord-257197-i9bucuma	97	8	76	76	CD
cord-257197-i9bucuma	97	9	]	]	-RRB-
cord-257197-i9bucuma	97	10	Antibodies	antibody	NNS
cord-257197-i9bucuma	97	11	/	/	SYM
cord-257197-i9bucuma	97	12	immunoglobulins	immunoglobulin	NNS
cord-257197-i9bucuma	97	13	are	be	VBP
cord-257197-i9bucuma	97	14	widely	widely	RB
cord-257197-i9bucuma	97	15	used	use	VBN
cord-257197-i9bucuma	97	16	due	due	IN
cord-257197-i9bucuma	97	17	to	to	IN
cord-257197-i9bucuma	97	18	their	-PRON-	PRP$
cord-257197-i9bucuma	97	19	high	high	JJ
cord-257197-i9bucuma	97	20	specificity	specificity	NN
cord-257197-i9bucuma	97	21	in	in	IN
cord-257197-i9bucuma	97	22	detecting	detect	VBG
cord-257197-i9bucuma	97	23	and	and	CC
cord-257197-i9bucuma	97	24	binding	bind	VBG
cord-257197-i9bucuma	97	25	to	to	IN
cord-257197-i9bucuma	97	26	specific	specific	JJ
cord-257197-i9bucuma	97	27	antigens	antigen	NNS
cord-257197-i9bucuma	97	28	and	and	CC
cord-257197-i9bucuma	97	29	have	have	VBP
cord-257197-i9bucuma	97	30	been	be	VBN
cord-257197-i9bucuma	97	31	successfully	successfully	RB
cord-257197-i9bucuma	97	32	employed	employ	VBN
cord-257197-i9bucuma	97	33	for	for	IN
cord-257197-i9bucuma	97	34	disease	disease	NN
cord-257197-i9bucuma	97	35	treatments	treatment	NNS
cord-257197-i9bucuma	97	36	as	as	IN
cord-257197-i9bucuma	97	37	antibody	antibody	NN
cord-257197-i9bucuma	97	38	drug	drug	NN
cord-257197-i9bucuma	97	39	conjugates	conjugate	NNS
cord-257197-i9bucuma	97	40	(	(	-LRB-
cord-257197-i9bucuma	97	41	ADCs	ADCs	NNP
cord-257197-i9bucuma	97	42	)	)	-RRB-
cord-257197-i9bucuma	97	43	,	,	,
cord-257197-i9bucuma	97	44	four	four	CD
cord-257197-i9bucuma	97	45	of	of	IN
cord-257197-i9bucuma	97	46	which	which	WDT
cord-257197-i9bucuma	97	47	are	be	VBP
cord-257197-i9bucuma	97	48	commercially	commercially	RB
cord-257197-i9bucuma	97	49	available	available	JJ
cord-257197-i9bucuma	97	50	.	.	.
cord-257197-i9bucuma	97	51	77	77	CD
cord-257197-i9bucuma	98	1	Since	since	IN
cord-257197-i9bucuma	98	2	protein	protein	NN
cord-257197-i9bucuma	98	3	structure	structure	NN
cord-257197-i9bucuma	98	4	defines	define	VBZ
cord-257197-i9bucuma	98	5	function	function	NN
cord-257197-i9bucuma	98	6	,	,	,
cord-257197-i9bucuma	98	7	any	any	DT
cord-257197-i9bucuma	98	8	structural	structural	JJ
cord-257197-i9bucuma	98	9	alterations	alteration	NNS
cord-257197-i9bucuma	98	10	due	due	JJ
cord-257197-i9bucuma	98	11	to	to	IN
cord-257197-i9bucuma	98	12	temperature	temperature	NN
cord-257197-i9bucuma	98	13	transitions	transition	NNS
cord-257197-i9bucuma	98	14	or	or	CC
cord-257197-i9bucuma	98	15	pH	ph	NN
cord-257197-i9bucuma	98	16	,	,	,
cord-257197-i9bucuma	98	17	limit	limit	VB
cord-257197-i9bucuma	98	18	the	the	DT
cord-257197-i9bucuma	98	19	chemistries	chemistry	NNS
cord-257197-i9bucuma	98	20	available	available	JJ
cord-257197-i9bucuma	98	21	for	for	IN
cord-257197-i9bucuma	98	22	attachment	attachment	NN
cord-257197-i9bucuma	98	23	to	to	IN
cord-257197-i9bucuma	98	24	NPs	NPs	NNP
cord-257197-i9bucuma	98	25	.	.	.
cord-257197-i9bucuma	99	1	General	general	JJ
cord-257197-i9bucuma	99	2	strategies	strategy	NNS
cord-257197-i9bucuma	99	3	for	for	IN
cord-257197-i9bucuma	99	4	binding	bind	VBG
cord-257197-i9bucuma	99	5	antibodies	antibody	NNS
cord-257197-i9bucuma	99	6	and	and	CC
cord-257197-i9bucuma	99	7	proteins	protein	NNS
cord-257197-i9bucuma	99	8	to	to	IN
cord-257197-i9bucuma	99	9	inorganic	inorganic	JJ
cord-257197-i9bucuma	99	10	surfaces	surface	NNS
cord-257197-i9bucuma	99	11	therefore	therefore	RB
cord-257197-i9bucuma	99	12	include	include	VBP
cord-257197-i9bucuma	99	13	covalent	covalent	JJ
cord-257197-i9bucuma	99	14	binding	bind	VBG
cord-257197-i9bucuma	99	15	to	to	IN
cord-257197-i9bucuma	99	16	a	a	DT
cord-257197-i9bucuma	99	17	modified	modify	VBN
cord-257197-i9bucuma	99	18	surface	surface	NN
cord-257197-i9bucuma	99	19	78	78	CD
cord-257197-i9bucuma	99	20	,	,	,
cord-257197-i9bucuma	99	21	79	79	CD
cord-257197-i9bucuma	99	22	,	,	,
cord-257197-i9bucuma	99	23	80	80	CD
cord-257197-i9bucuma	99	24	or	or	CC
cord-257197-i9bucuma	99	25	by	by	IN
cord-257197-i9bucuma	99	26	physical	physical	JJ
cord-257197-i9bucuma	99	27	adsorption	adsorption	NN
cord-257197-i9bucuma	99	28	promoted	promote	VBN
cord-257197-i9bucuma	99	29	by	by	IN
cord-257197-i9bucuma	99	30	electrostatic	electrostatic	JJ
cord-257197-i9bucuma	99	31	interactions	interaction	NNS
cord-257197-i9bucuma	99	32	.	.	.
cord-257197-i9bucuma	100	1	79	79	CD
cord-257197-i9bucuma	101	1	The	the	DT
cord-257197-i9bucuma	101	2	orientation	orientation	NN
cord-257197-i9bucuma	101	3	of	of	IN
cord-257197-i9bucuma	101	4	the	the	DT
cord-257197-i9bucuma	101	5	antibody	antibody	NN
cord-257197-i9bucuma	101	6	is	be	VBZ
cord-257197-i9bucuma	101	7	more	more	RBR
cord-257197-i9bucuma	101	8	important	important	JJ
cord-257197-i9bucuma	101	9	for	for	IN
cord-257197-i9bucuma	101	10	its	-PRON-	PRP$
cord-257197-i9bucuma	101	11	functioning	functioning	NN
cord-257197-i9bucuma	101	12	than	than	IN
cord-257197-i9bucuma	101	13	its	-PRON-	PRP$
cord-257197-i9bucuma	101	14	coverage	coverage	NN
cord-257197-i9bucuma	101	15	on	on	IN
cord-257197-i9bucuma	101	16	the	the	DT
cord-257197-i9bucuma	101	17	surface	surface	NN
cord-257197-i9bucuma	101	18	and	and	CC
cord-257197-i9bucuma	101	19	hence	hence	RB
cord-257197-i9bucuma	101	20	orienting	orient	VBG
cord-257197-i9bucuma	101	21	covalent	covalent	JJ
cord-257197-i9bucuma	101	22	binding	bind	VBG
cord-257197-i9bucuma	101	23	strategies	strategy	NNS
cord-257197-i9bucuma	101	24	are	be	VBP
cord-257197-i9bucuma	101	25	more	more	RBR
cord-257197-i9bucuma	101	26	widely	widely	RB
cord-257197-i9bucuma	101	27	employed	employ	VBN
cord-257197-i9bucuma	101	28	.	.	.
cord-257197-i9bucuma	102	1	79	79	CD
cord-257197-i9bucuma	103	1	J	J	NNP
cord-257197-i9bucuma	103	2	o	o	NN
cord-257197-i9bucuma	103	3	u	u	NN
cord-257197-i9bucuma	103	4	r	r	NN
cord-257197-i9bucuma	103	5	n	n	NN
cord-257197-i9bucuma	103	6	a	a	DT
cord-257197-i9bucuma	103	7	l	l	NN
cord-257197-i9bucuma	103	8	P	p	NN
cord-257197-i9bucuma	103	9	r	r	NN
cord-257197-i9bucuma	103	10	e	e	NN
cord-257197-i9bucuma	103	11	-p	-p	NN
cord-257197-i9bucuma	103	12	r	r	NN
cord-257197-i9bucuma	103	13	o	o	NN
cord-257197-i9bucuma	103	14	o	o	NN
cord-257197-i9bucuma	103	15	f	f	NN
cord-257197-i9bucuma	103	16	Finetti	Finetti	NNP
cord-257197-i9bucuma	103	17	et	et	NNP
cord-257197-i9bucuma	103	18	al	al	NNP
cord-257197-i9bucuma	103	19	.	.	.
cord-257197-i9bucuma	104	1	80	80	CD
cord-257197-i9bucuma	104	2	used	use	VBN
cord-257197-i9bucuma	104	3	"	"	``
cord-257197-i9bucuma	104	4	click	click	VB
cord-257197-i9bucuma	104	5	"	"	''
cord-257197-i9bucuma	104	6	chemistry	chemistry	NN
cord-257197-i9bucuma	104	7	to	to	TO
cord-257197-i9bucuma	104	8	immobilize	immobilize	VB
cord-257197-i9bucuma	104	9	anti	anti	JJ
cord-257197-i9bucuma	104	10	CD-63	CD-63	NNP
cord-257197-i9bucuma	104	11	and	and	CC
cord-257197-i9bucuma	104	12	anti	anti	JJ
cord-257197-i9bucuma	104	13	-	-	JJ
cord-257197-i9bucuma	104	14	rabbit	rabbit	JJ
cord-257197-i9bucuma	104	15	-	-	HYPH
cord-257197-i9bucuma	104	16	IgG	igg	NN
cord-257197-i9bucuma	104	17	on	on	IN
cord-257197-i9bucuma	104	18	the	the	DT
cord-257197-i9bucuma	104	19	surface	surface	NN
cord-257197-i9bucuma	104	20	of	of	IN
cord-257197-i9bucuma	104	21	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	104	22	.	.	.
cord-257197-i9bucuma	105	1	Thus	thus	RB
cord-257197-i9bucuma	105	2	,	,	,
cord-257197-i9bucuma	105	3	using	use	VBG
cord-257197-i9bucuma	105	4	the	the	DT
cord-257197-i9bucuma	105	5	benefits	benefit	NNS
cord-257197-i9bucuma	105	6	of	of	IN
cord-257197-i9bucuma	105	7	click	click	NN
cord-257197-i9bucuma	105	8	chemistry	chemistry	NN
cord-257197-i9bucuma	105	9	,	,	,
cord-257197-i9bucuma	105	10	antibodies	antibody	NNS
cord-257197-i9bucuma	105	11	immobilized	immobilize	VBN
cord-257197-i9bucuma	105	12	NPs	NPs	NNPS
cord-257197-i9bucuma	105	13	can	can	MD
cord-257197-i9bucuma	105	14	be	be	VB
cord-257197-i9bucuma	105	15	produced	produce	VBN
cord-257197-i9bucuma	105	16	for	for	IN
cord-257197-i9bucuma	105	17	a	a	DT
cord-257197-i9bucuma	105	18	wide	wide	JJ
cord-257197-i9bucuma	105	19	range	range	NN
cord-257197-i9bucuma	105	20	of	of	IN
cord-257197-i9bucuma	105	21	applications	application	NNS
cord-257197-i9bucuma	105	22	.	.	.
cord-257197-i9bucuma	106	1	Antibody	antibody	NN
cord-257197-i9bucuma	106	2	immobilized	immobilize	VBN
cord-257197-i9bucuma	106	3	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	106	4	are	be	VBP
cord-257197-i9bucuma	106	5	also	also	RB
cord-257197-i9bucuma	106	6	widely	widely	RB
cord-257197-i9bucuma	106	7	used	use	VBN
cord-257197-i9bucuma	106	8	in	in	IN
cord-257197-i9bucuma	106	9	immunostaining	immunostaine	VBG
cord-257197-i9bucuma	106	10	for	for	IN
cord-257197-i9bucuma	106	11	analysis	analysis	NN
cord-257197-i9bucuma	106	12	using	use	VBG
cord-257197-i9bucuma	106	13	electron	electron	NN
cord-257197-i9bucuma	106	14	microscopy	microscopy	NN
cord-257197-i9bucuma	106	15	,	,	,
cord-257197-i9bucuma	106	16	and	and	CC
cord-257197-i9bucuma	106	17	plasmon	plasmon	JJ
cord-257197-i9bucuma	106	18	resonance	resonance	NN
cord-257197-i9bucuma	106	19	mediated	mediate	VBN
cord-257197-i9bucuma	106	20	confocal	confocal	JJ
cord-257197-i9bucuma	106	21	imaging	imaging	NN
cord-257197-i9bucuma	106	22	.	.	.
cord-257197-i9bucuma	107	1	31	31	CD
cord-257197-i9bucuma	107	2	,	,	,
cord-257197-i9bucuma	107	3	81	81	CD
cord-257197-i9bucuma	107	4	,	,	,
cord-257197-i9bucuma	107	5	82	82	CD
cord-257197-i9bucuma	107	6	Antibodies	antibody	NNS
cord-257197-i9bucuma	107	7	tagged	tag	VBN
cord-257197-i9bucuma	107	8	with	with	IN
cord-257197-i9bucuma	107	9	fluorescence	fluorescence	NN
cord-257197-i9bucuma	107	10	molecule	molecule	NN
cord-257197-i9bucuma	107	11	on	on	IN
cord-257197-i9bucuma	107	12	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	107	13	allows	allow	VBZ
cord-257197-i9bucuma	107	14	for	for	IN
cord-257197-i9bucuma	107	15	dual	dual	JJ
cord-257197-i9bucuma	107	16	imaging	imaging	NN
cord-257197-i9bucuma	107	17	,	,	,
cord-257197-i9bucuma	107	18	reducing	reduce	VBG
cord-257197-i9bucuma	107	19	cost	cost	NN
cord-257197-i9bucuma	107	20	and	and	CC
cord-257197-i9bucuma	107	21	time	time	NN
cord-257197-i9bucuma	107	22	.	.	.
cord-257197-i9bucuma	108	1	NPs	NPs	NNP
cord-257197-i9bucuma	108	2	are	be	VBP
cord-257197-i9bucuma	108	3	commonly	commonly	RB
cord-257197-i9bucuma	108	4	coated	coat	VBN
cord-257197-i9bucuma	108	5	with	with	IN
cord-257197-i9bucuma	108	6	nucleic	nucleic	JJ
cord-257197-i9bucuma	108	7	acids	acid	NNS
cord-257197-i9bucuma	108	8	such	such	JJ
cord-257197-i9bucuma	108	9	as	as	IN
cord-257197-i9bucuma	108	10	DNA	DNA	NNP
cord-257197-i9bucuma	108	11	,	,	,
cord-257197-i9bucuma	108	12	dsRNA	dsrna	NN
cord-257197-i9bucuma	108	13	,	,	,
cord-257197-i9bucuma	108	14	ssRNA	ssRNA	NNP
cord-257197-i9bucuma	108	15	,	,	,
cord-257197-i9bucuma	108	16	siRNA	siRNA	NNP
cord-257197-i9bucuma	108	17	,	,	,
cord-257197-i9bucuma	108	18	mRNA	mRNA	NNP
cord-257197-i9bucuma	108	19	,	,	,
cord-257197-i9bucuma	108	20	and	and	CC
cord-257197-i9bucuma	108	21	microRNA	microRNA	NNP
cord-257197-i9bucuma	108	22	,	,	,
cord-257197-i9bucuma	108	23	as	as	IN
cord-257197-i9bucuma	108	24	they	-PRON-	PRP
cord-257197-i9bucuma	108	25	facilitate	facilitate	VBP
cord-257197-i9bucuma	108	26	the	the	DT
cord-257197-i9bucuma	108	27	delivery	delivery	NN
cord-257197-i9bucuma	108	28	of	of	IN
cord-257197-i9bucuma	108	29	the	the	DT
cord-257197-i9bucuma	108	30	nucleic	nucleic	JJ
cord-257197-i9bucuma	108	31	acids	acid	NNS
cord-257197-i9bucuma	108	32	into	into	IN
cord-257197-i9bucuma	108	33	cells	cell	NNS
cord-257197-i9bucuma	108	34	or	or	CC
cord-257197-i9bucuma	108	35	for	for	IN
cord-257197-i9bucuma	108	36	use	use	NN
cord-257197-i9bucuma	108	37	in	in	IN
cord-257197-i9bucuma	108	38	binding	bind	VBG
cord-257197-i9bucuma	108	39	assays	assay	NNS
cord-257197-i9bucuma	108	40	.	.	.
cord-257197-i9bucuma	109	1	DNA	DNA	NNP
cord-257197-i9bucuma	109	2	grafted	graft	VBN
cord-257197-i9bucuma	109	3	polymers	polymer	NNS
cord-257197-i9bucuma	109	4	such	such	JJ
cord-257197-i9bucuma	109	5	as	as	IN
cord-257197-i9bucuma	109	6	poly(acrylic	poly(acrylic	JJ
cord-257197-i9bucuma	109	7	acid	acid	NN
cord-257197-i9bucuma	109	8	)	)	-RRB-
cord-257197-i9bucuma	109	9	embedded	embed	VBN
cord-257197-i9bucuma	109	10	DNA	dna	NN
cord-257197-i9bucuma	109	11	are	be	VBP
cord-257197-i9bucuma	109	12	also	also	RB
cord-257197-i9bucuma	109	13	used	use	VBN
cord-257197-i9bucuma	109	14	for	for	IN
cord-257197-i9bucuma	109	15	functionalizing	functionalize	VBG
cord-257197-i9bucuma	109	16	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	109	17	as	as	IN
cord-257197-i9bucuma	109	18	they	-PRON-	PRP
cord-257197-i9bucuma	109	19	facilitate	facilitate	VBP
cord-257197-i9bucuma	109	20	polyvalent	polyvalent	JJ
cord-257197-i9bucuma	109	21	DNA	dna	NN
cord-257197-i9bucuma	109	22	nanostructure	nanostructure	NN
cord-257197-i9bucuma	109	23	formation	formation	NN
cord-257197-i9bucuma	109	24	.	.	.
cord-257197-i9bucuma	110	1	83	83	CD
cord-257197-i9bucuma	111	1	A	a	DT
cord-257197-i9bucuma	111	2	common	common	JJ
cord-257197-i9bucuma	111	3	strategy	strategy	NN
cord-257197-i9bucuma	111	4	for	for	IN
cord-257197-i9bucuma	111	5	functionalizing	functionalize	VBG
cord-257197-i9bucuma	111	6	NPs	NPs	NNP
cord-257197-i9bucuma	111	7	with	with	IN
cord-257197-i9bucuma	111	8	nucleic	nucleic	JJ
cord-257197-i9bucuma	111	9	acids	acid	NNS
cord-257197-i9bucuma	111	10	is	be	VBZ
cord-257197-i9bucuma	111	11	to	to	TO
cord-257197-i9bucuma	111	12	utilize	utilize	VB
cord-257197-i9bucuma	111	13	the	the	DT
cord-257197-i9bucuma	111	14	electrostatic	electrostatic	JJ
cord-257197-i9bucuma	111	15	interactions	interaction	NNS
cord-257197-i9bucuma	111	16	between	between	IN
cord-257197-i9bucuma	111	17	the	the	DT
cord-257197-i9bucuma	111	18	negatively	negatively	RB
cord-257197-i9bucuma	111	19	charged	charge	VBN
cord-257197-i9bucuma	111	20	nucleic	nucleic	JJ
cord-257197-i9bucuma	111	21	acids	acid	NNS
cord-257197-i9bucuma	111	22	and	and	CC
cord-257197-i9bucuma	111	23	cationic	cationic	JJ
cord-257197-i9bucuma	111	24	NPs	NPs	NNPS
cord-257197-i9bucuma	111	25	which	which	WDT
cord-257197-i9bucuma	111	26	mediates	mediate	VBZ
cord-257197-i9bucuma	111	27	their	-PRON-	PRP$
cord-257197-i9bucuma	111	28	adsorption	adsorption	NN
cord-257197-i9bucuma	111	29	to	to	IN
cord-257197-i9bucuma	111	30	NPs	NPs	NNP
cord-257197-i9bucuma	111	31	.	.	.
cord-257197-i9bucuma	112	1	84	84	CD
cord-257197-i9bucuma	112	2	,	,	,
cord-257197-i9bucuma	112	3	85	85	CD
cord-257197-i9bucuma	113	1	This	this	DT
cord-257197-i9bucuma	113	2	does	do	VBZ
cord-257197-i9bucuma	113	3	not	not	RB
cord-257197-i9bucuma	113	4	require	require	VB
cord-257197-i9bucuma	113	5	extensive	extensive	JJ
cord-257197-i9bucuma	113	6	modification	modification	NN
cord-257197-i9bucuma	113	7	of	of	IN
cord-257197-i9bucuma	113	8	the	the	DT
cord-257197-i9bucuma	113	9	nucleic	nucleic	JJ
cord-257197-i9bucuma	113	10	acids	acid	NNS
cord-257197-i9bucuma	113	11	.	.	.
cord-257197-i9bucuma	114	1	86	86	CD
cord-257197-i9bucuma	115	1	Recently	recently	RB
cord-257197-i9bucuma	115	2	nucleic	nucleic	JJ
cord-257197-i9bucuma	115	3	acids	acid	NNS
cord-257197-i9bucuma	115	4	have	have	VBP
cord-257197-i9bucuma	115	5	also	also	RB
cord-257197-i9bucuma	115	6	been	be	VBN
cord-257197-i9bucuma	115	7	identified	identify	VBN
cord-257197-i9bucuma	115	8	as	as	IN
cord-257197-i9bucuma	115	9	templates	template	NNS
cord-257197-i9bucuma	115	10	that	that	WDT
cord-257197-i9bucuma	115	11	control	control	VBP
cord-257197-i9bucuma	115	12	and	and	CC
cord-257197-i9bucuma	115	13	facilitate	facilitate	VB
cord-257197-i9bucuma	115	14	inorganic	inorganic	JJ
cord-257197-i9bucuma	115	15	NPs	NPs	NNP
cord-257197-i9bucuma	115	16	synthesis	synthesis	NN
cord-257197-i9bucuma	115	17	.	.	.
cord-257197-i9bucuma	116	1	87	87	CD
cord-257197-i9bucuma	116	2	Aptamers	Aptamers	NNPS
cord-257197-i9bucuma	116	3	that	that	WDT
cord-257197-i9bucuma	116	4	bind	bind	VBP
cord-257197-i9bucuma	116	5	with	with	IN
cord-257197-i9bucuma	116	6	high	high	JJ
cord-257197-i9bucuma	116	7	affinity	affinity	NN
cord-257197-i9bucuma	116	8	and	and	CC
cord-257197-i9bucuma	116	9	specificity	specificity	NN
cord-257197-i9bucuma	116	10	to	to	IN
cord-257197-i9bucuma	116	11	proteins	protein	NNS
cord-257197-i9bucuma	116	12	and	and	CC
cord-257197-i9bucuma	116	13	peptides	peptide	NNS
cord-257197-i9bucuma	116	14	are	be	VBP
cord-257197-i9bucuma	116	15	commonly	commonly	RB
cord-257197-i9bucuma	116	16	conjugated	conjugate	VBN
cord-257197-i9bucuma	116	17	to	to	IN
cord-257197-i9bucuma	116	18	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	116	19	and	and	CC
cord-257197-i9bucuma	116	20	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	116	21	for	for	IN
cord-257197-i9bucuma	116	22	detection	detection	NN
cord-257197-i9bucuma	116	23	of	of	IN
cord-257197-i9bucuma	116	24	molecules	molecule	NNS
cord-257197-i9bucuma	116	25	using	use	VBG
cord-257197-i9bucuma	116	26	colorimetric	colorimetric	JJ
cord-257197-i9bucuma	116	27	binding	binding	JJ
cord-257197-i9bucuma	116	28	assays	assay	NNS
cord-257197-i9bucuma	116	29	88	88	CD
cord-257197-i9bucuma	116	30	,	,	,
cord-257197-i9bucuma	116	31	89	89	CD
cord-257197-i9bucuma	116	32	and	and	CC
cord-257197-i9bucuma	116	33	magnetic	magnetic	JJ
cord-257197-i9bucuma	116	34	isolation	isolation	NN
cord-257197-i9bucuma	116	35	90	90	CD
cord-257197-i9bucuma	116	36	,	,	,
cord-257197-i9bucuma	116	37	respectively	respectively	RB
cord-257197-i9bucuma	116	38	.	.	.
cord-257197-i9bucuma	117	1	J	J	NNP
cord-257197-i9bucuma	117	2	o	o	NN
cord-257197-i9bucuma	117	3	u	u	NN
cord-257197-i9bucuma	117	4	r	r	NN
cord-257197-i9bucuma	117	5	n	n	NN
cord-257197-i9bucuma	117	6	a	a	DT
cord-257197-i9bucuma	117	7	l	l	NN
cord-257197-i9bucuma	117	8	P	p	NN
cord-257197-i9bucuma	117	9	r	r	NN
cord-257197-i9bucuma	117	10	e	e	NN
cord-257197-i9bucuma	117	11	-p	-p	NN
cord-257197-i9bucuma	117	12	r	r	NN
cord-257197-i9bucuma	117	13	o	o	NN
cord-257197-i9bucuma	117	14	o	o	NN
cord-257197-i9bucuma	117	15	f	f	NN
cord-257197-i9bucuma	117	16	 	 	_SP
cord-257197-i9bucuma	118	1	In	in	IN
cord-257197-i9bucuma	118	2	vitro	vitro	FW
cord-257197-i9bucuma	118	3	studies	study	NNS
cord-257197-i9bucuma	118	4	are	be	VBP
cord-257197-i9bucuma	118	5	often	often	RB
cord-257197-i9bucuma	118	6	indicators	indicator	NNS
cord-257197-i9bucuma	118	7	of	of	IN
cord-257197-i9bucuma	118	8	potential	potential	JJ
cord-257197-i9bucuma	118	9	outcomes	outcome	NNS
cord-257197-i9bucuma	118	10	in	in	IN
cord-257197-i9bucuma	118	11	animal	animal	NN
cord-257197-i9bucuma	118	12	studies	study	NNS
cord-257197-i9bucuma	118	13	and	and	CC
cord-257197-i9bucuma	118	14	provide	provide	VB
cord-257197-i9bucuma	118	15	mechanistic	mechanistic	JJ
cord-257197-i9bucuma	118	16	information	information	NN
cord-257197-i9bucuma	118	17	at	at	IN
cord-257197-i9bucuma	118	18	the	the	DT
cord-257197-i9bucuma	118	19	cellular	cellular	JJ
cord-257197-i9bucuma	118	20	level	level	NN
cord-257197-i9bucuma	118	21	.	.	.
cord-257197-i9bucuma	119	1	They	-PRON-	PRP
cord-257197-i9bucuma	119	2	allow	allow	VBP
cord-257197-i9bucuma	119	3	researchers	researcher	NNS
cord-257197-i9bucuma	119	4	to	to	TO
cord-257197-i9bucuma	119	5	explore	explore	VB
cord-257197-i9bucuma	119	6	the	the	DT
cord-257197-i9bucuma	119	7	effect	effect	NN
cord-257197-i9bucuma	119	8	of	of	IN
cord-257197-i9bucuma	119	9	different	different	JJ
cord-257197-i9bucuma	119	10	doses	dose	NNS
cord-257197-i9bucuma	119	11	,	,	,
cord-257197-i9bucuma	119	12	chemicals	chemical	NNS
cord-257197-i9bucuma	119	13	at	at	IN
cord-257197-i9bucuma	119	14	relatively	relatively	RB
cord-257197-i9bucuma	119	15	lower	low	JJR
cord-257197-i9bucuma	119	16	cost	cost	NN
cord-257197-i9bucuma	119	17	and	and	CC
cord-257197-i9bucuma	119	18	reduced	reduce	VBN
cord-257197-i9bucuma	119	19	time	time	NN
cord-257197-i9bucuma	119	20	.	.	.
cord-257197-i9bucuma	120	1	They	-PRON-	PRP
cord-257197-i9bucuma	120	2	also	also	RB
cord-257197-i9bucuma	120	3	allow	allow	VBP
cord-257197-i9bucuma	120	4	for	for	IN
cord-257197-i9bucuma	120	5	probing	probe	VBG
cord-257197-i9bucuma	120	6	POPC	POPC	NNP
cord-257197-i9bucuma	120	7	,	,	,
cord-257197-i9bucuma	120	8	1-palmitoyl-2-oleoyl	1-palmitoyl-2-oleoyl	CD
cord-257197-i9bucuma	120	9	-	-	HYPH
cord-257197-i9bucuma	120	10	sn	sn	NN
cord-257197-i9bucuma	120	11	-	-	HYPH
cord-257197-i9bucuma	120	12	glycero-3-phosphocholine	glycero-3-phosphocholine	NN
cord-257197-i9bucuma	120	13	;	;	:
cord-257197-i9bucuma	120	14	POPG	POPG	NNP
cord-257197-i9bucuma	120	15	,	,	,
cord-257197-i9bucuma	120	16	1-palmitoyl-2-oleoyl	1-palmitoyl-2-oleoyl	CD
cord-257197-i9bucuma	120	17	-	-	HYPH
cord-257197-i9bucuma	120	18	sn	sn	NN
cord-257197-i9bucuma	120	19	-	-	HYPH
cord-257197-i9bucuma	120	20	glycero-3-phosphoglycerol	glycero-3-phosphoglycerol	JJ
cord-257197-i9bucuma	120	21	;	;	:
cord-257197-i9bucuma	120	22	DOPE	DOPE	NNP
cord-257197-i9bucuma	120	23	,	,	,
cord-257197-i9bucuma	120	24	Dioleoylphosphatidylethanolamine	Dioleoylphosphatidylethanolamine	NNP
cord-257197-i9bucuma	120	25	;	;	:
cord-257197-i9bucuma	120	26	OQLCS	OQLCS	NNP
cord-257197-i9bucuma	120	27	,	,	,
cord-257197-i9bucuma	120	28	octadecyl	octadecyl	NN
cord-257197-i9bucuma	120	29	-	-	HYPH
cord-257197-i9bucuma	120	30	quaternized	quaternize	VBN
cord-257197-i9bucuma	120	31	lysine	lysine	NN
cord-257197-i9bucuma	120	32	modified	modify	VBN
cord-257197-i9bucuma	120	33	chitosan	chitosan	NN
cord-257197-i9bucuma	120	34	;	;	:
cord-257197-i9bucuma	120	35	TAT	TAT	NNP
cord-257197-i9bucuma	120	36	,	,	,
cord-257197-i9bucuma	120	37	Transactivator	Transactivator	NNP
cord-257197-i9bucuma	120	38	of	of	IN
cord-257197-i9bucuma	120	39	transcription	transcription	NN
cord-257197-i9bucuma	120	40	;	;	:
cord-257197-i9bucuma	120	41	CPP	CPP	NNP
cord-257197-i9bucuma	120	42	,	,	,
cord-257197-i9bucuma	120	43	Cell	cell	NN
cord-257197-i9bucuma	120	44	penetrating	penetrating	JJ
cord-257197-i9bucuma	120	45	peptide	peptide	NN
cord-257197-i9bucuma	120	46	;	;	:
cord-257197-i9bucuma	120	47	ScFvEGFR	ScFvEGFR	NNP
cord-257197-i9bucuma	120	48	,	,	,
cord-257197-i9bucuma	120	49	short	short	JJ
cord-257197-i9bucuma	120	50	chain	chain	NN
cord-257197-i9bucuma	120	51	variable	variable	NN
cord-257197-i9bucuma	120	52	,	,	,
cord-257197-i9bucuma	120	53	anti	anti	JJ
cord-257197-i9bucuma	120	54	-	-	JJ
cord-257197-i9bucuma	120	55	EFGR	efgr	JJ
cord-257197-i9bucuma	121	1	the	the	DT
cord-257197-i9bucuma	121	2	underlying	underlie	VBG
cord-257197-i9bucuma	121	3	mechanisms	mechanism	NNS
cord-257197-i9bucuma	121	4	leading	lead	VBG
cord-257197-i9bucuma	121	5	to	to	IN
cord-257197-i9bucuma	121	6	toxicity	toxicity	NN
cord-257197-i9bucuma	121	7	,	,	,
cord-257197-i9bucuma	121	8	immunogenicity	immunogenicity	NN
cord-257197-i9bucuma	121	9	,	,	,
cord-257197-i9bucuma	121	10	metabolic	metabolic	JJ
cord-257197-i9bucuma	121	11	changes	change	NNS
cord-257197-i9bucuma	121	12	and	and	CC
cord-257197-i9bucuma	121	13	analyzing	analyze	VBG
cord-257197-i9bucuma	121	14	gene	gene	NN
cord-257197-i9bucuma	121	15	expression	expression	NN
cord-257197-i9bucuma	121	16	profiles	profile	NNS
cord-257197-i9bucuma	121	17	.	.	.
cord-257197-i9bucuma	122	1	These	these	DT
cord-257197-i9bucuma	122	2	cell	cell	NN
cord-257197-i9bucuma	122	3	culture	culture	NN
cord-257197-i9bucuma	122	4	studies	study	NNS
cord-257197-i9bucuma	122	5	reduce	reduce	VBP
cord-257197-i9bucuma	122	6	the	the	DT
cord-257197-i9bucuma	122	7	number	number	NN
cord-257197-i9bucuma	122	8	and	and	CC
cord-257197-i9bucuma	122	9	cost	cost	NN
cord-257197-i9bucuma	122	10	of	of	IN
cord-257197-i9bucuma	122	11	animals	animal	NNS
cord-257197-i9bucuma	122	12	required	require	VBN
cord-257197-i9bucuma	122	13	to	to	TO
cord-257197-i9bucuma	122	14	statistically	statistically	RB
cord-257197-i9bucuma	122	15	assess	assess	VB
cord-257197-i9bucuma	122	16	the	the	DT
cord-257197-i9bucuma	122	17	effect	effect	NN
cord-257197-i9bucuma	122	18	of	of	IN
cord-257197-i9bucuma	122	19	NPs	NPs	NNPS
cord-257197-i9bucuma	122	20	.	.	.
cord-257197-i9bucuma	123	1	91	91	CD
cord-257197-i9bucuma	123	2	NPs	np	NNS
cord-257197-i9bucuma	123	3	on	on	IN
cord-257197-i9bucuma	123	4	the	the	DT
cord-257197-i9bucuma	123	5	other	other	JJ
cord-257197-i9bucuma	123	6	hand	hand	NN
cord-257197-i9bucuma	123	7	encounter	encounter	NN
cord-257197-i9bucuma	123	8	a	a	DT
cord-257197-i9bucuma	123	9	very	very	RB
cord-257197-i9bucuma	123	10	complex	complex	JJ
cord-257197-i9bucuma	123	11	environment	environment	NN
cord-257197-i9bucuma	123	12	in	in	IN
cord-257197-i9bucuma	123	13	vivo	vivo	NN
cord-257197-i9bucuma	123	14	which	which	WDT
cord-257197-i9bucuma	123	15	can	can	MD
cord-257197-i9bucuma	123	16	not	not	RB
cord-257197-i9bucuma	123	17	be	be	VB
cord-257197-i9bucuma	123	18	mimicked	mimic	VBN
cord-257197-i9bucuma	123	19	accurately	accurately	RB
cord-257197-i9bucuma	123	20	in	in	IN
cord-257197-i9bucuma	123	21	vitro	vitro	FW
cord-257197-i9bucuma	123	22	.	.	.
cord-257197-i9bucuma	124	1	And	and	CC
cord-257197-i9bucuma	124	2	therefore	therefore	RB
cord-257197-i9bucuma	124	3	,	,	,
cord-257197-i9bucuma	124	4	there	there	EX
cord-257197-i9bucuma	124	5	are	be	VBP
cord-257197-i9bucuma	124	6	obvious	obvious	JJ
cord-257197-i9bucuma	124	7	discrepancies	discrepancy	NNS
cord-257197-i9bucuma	124	8	due	due	JJ
cord-257197-i9bucuma	124	9	to	to	IN
cord-257197-i9bucuma	124	10	these	these	DT
cord-257197-i9bucuma	124	11	inherent	inherent	JJ
cord-257197-i9bucuma	124	12	differences	difference	NNS
cord-257197-i9bucuma	124	13	between	between	IN
cord-257197-i9bucuma	124	14	in	in	IN
cord-257197-i9bucuma	124	15	vitro	vitro	FW
cord-257197-i9bucuma	124	16	and	and	CC
cord-257197-i9bucuma	124	17	in	in	IN
cord-257197-i9bucuma	124	18	vivo	vivo	NN
cord-257197-i9bucuma	124	19	environments	environment	NNS
cord-257197-i9bucuma	124	20	.	.	.
cord-257197-i9bucuma	125	1	Khlebtsov	Khlebtsov	NNP
cord-257197-i9bucuma	125	2	et	et	NNP
cord-257197-i9bucuma	125	3	al	al	NNP
cord-257197-i9bucuma	125	4	.	.	.
cord-257197-i9bucuma	126	1	92	92	CD
cord-257197-i9bucuma	126	2	have	have	VBP
cord-257197-i9bucuma	126	3	examined	examine	VBN
cord-257197-i9bucuma	126	4	the	the	DT
cord-257197-i9bucuma	126	5	lack	lack	NN
cord-257197-i9bucuma	126	6	of	of	IN
cord-257197-i9bucuma	126	7	correlation	correlation	NN
cord-257197-i9bucuma	126	8	between	between	IN
cord-257197-i9bucuma	126	9	in	in	IN
cord-257197-i9bucuma	126	10	vitro	vitro	FW
cord-257197-i9bucuma	126	11	and	and	CC
cord-257197-i9bucuma	126	12	in	in	IN
cord-257197-i9bucuma	126	13	vivo	vivo	NN
cord-257197-i9bucuma	126	14	behavior	behavior	NN
cord-257197-i9bucuma	126	15	of	of	IN
cord-257197-i9bucuma	126	16	NPs	NPs	NNP
cord-257197-i9bucuma	126	17	.	.	.
cord-257197-i9bucuma	127	1	They	-PRON-	PRP
cord-257197-i9bucuma	127	2	emphasize	emphasize	VBP
cord-257197-i9bucuma	127	3	on	on	IN
cord-257197-i9bucuma	127	4	the	the	DT
cord-257197-i9bucuma	127	5	need	need	NN
cord-257197-i9bucuma	127	6	for	for	IN
cord-257197-i9bucuma	127	7	systematization	systematization	NN
cord-257197-i9bucuma	127	8	of	of	IN
cord-257197-i9bucuma	127	9	data	datum	NNS
cord-257197-i9bucuma	127	10	obtained	obtain	VBN
cord-257197-i9bucuma	127	11	from	from	IN
cord-257197-i9bucuma	127	12	various	various	JJ
cord-257197-i9bucuma	127	13	studies	study	NNS
cord-257197-i9bucuma	127	14	on	on	IN
cord-257197-i9bucuma	127	15	NPs	NPs	NNP
cord-257197-i9bucuma	127	16	,	,	,
cord-257197-i9bucuma	127	17	to	to	TO
cord-257197-i9bucuma	127	18	gain	gain	VB
cord-257197-i9bucuma	127	19	a	a	DT
cord-257197-i9bucuma	127	20	fundamental	fundamental	JJ
cord-257197-i9bucuma	127	21	understanding	understanding	NN
cord-257197-i9bucuma	127	22	of	of	IN
cord-257197-i9bucuma	127	23	factors	factor	NNS
cord-257197-i9bucuma	127	24	affecting	affect	VBG
cord-257197-i9bucuma	127	25	their	-PRON-	PRP$
cord-257197-i9bucuma	127	26	biointeractions	biointeraction	NNS
cord-257197-i9bucuma	127	27	.	.	.
cord-257197-i9bucuma	128	1	The	the	DT
cord-257197-i9bucuma	128	2	inconsistencies	inconsistency	NNS
cord-257197-i9bucuma	128	3	observed	observe	VBD
cord-257197-i9bucuma	128	4	between	between	IN
cord-257197-i9bucuma	128	5	their	-PRON-	PRP$
cord-257197-i9bucuma	128	6	effects	effect	NNS
cord-257197-i9bucuma	128	7	in	in	IN
cord-257197-i9bucuma	128	8	vitro	vitro	FW
cord-257197-i9bucuma	128	9	and	and	CC
cord-257197-i9bucuma	128	10	in	in	IN
cord-257197-i9bucuma	128	11	vivo	vivo	NN
cord-257197-i9bucuma	128	12	is	be	VBZ
cord-257197-i9bucuma	128	13	also	also	RB
cord-257197-i9bucuma	128	14	due	due	JJ
cord-257197-i9bucuma	128	15	to	to	IN
cord-257197-i9bucuma	128	16	differences	difference	NNS
cord-257197-i9bucuma	128	17	in	in	IN
cord-257197-i9bucuma	128	18	experimental	experimental	JJ
cord-257197-i9bucuma	128	19	factors	factor	NNS
cord-257197-i9bucuma	128	20	.	.	.
cord-257197-i9bucuma	129	1	[	[	-LRB-
cord-257197-i9bucuma	129	2	93	93	CD
cord-257197-i9bucuma	129	3	]	]	-RRB-
cord-257197-i9bucuma	129	4	[	[	-LRB-
cord-257197-i9bucuma	129	5	94	94	CD
cord-257197-i9bucuma	129	6	]	]	-RRB-
cord-257197-i9bucuma	129	7	[	[	-LRB-
cord-257197-i9bucuma	129	8	95	95	CD
cord-257197-i9bucuma	129	9	]	]	-RRB-
cord-257197-i9bucuma	130	1	[	[	-LRB-
cord-257197-i9bucuma	130	2	96	96	CD
cord-257197-i9bucuma	130	3	]	]	-RRB-
cord-257197-i9bucuma	130	4	[	[	-LRB-
cord-257197-i9bucuma	130	5	97	97	CD
cord-257197-i9bucuma	130	6	]	]	-RRB-
cord-257197-i9bucuma	131	1	For	for	IN
cord-257197-i9bucuma	131	2	example	example	NN
cord-257197-i9bucuma	131	3	,	,	,
cord-257197-i9bucuma	131	4	one	one	CD
cord-257197-i9bucuma	131	5	basic	basic	JJ
cord-257197-i9bucuma	131	6	consideration	consideration	NN
cord-257197-i9bucuma	131	7	is	be	VBZ
cord-257197-i9bucuma	131	8	to	to	TO
cord-257197-i9bucuma	131	9	use	use	VB
cord-257197-i9bucuma	131	10	the	the	DT
cord-257197-i9bucuma	131	11	cell	cell	NN
cord-257197-i9bucuma	131	12	lines/	lines/	CD
cord-257197-i9bucuma	131	13	primary	primary	JJ
cord-257197-i9bucuma	131	14	cell	cell	NN
cord-257197-i9bucuma	131	15	types	type	NNS
cord-257197-i9bucuma	131	16	for	for	IN
cord-257197-i9bucuma	131	17	in	in	FW
cord-257197-i9bucuma	131	18	vitro	vitro	FW
cord-257197-i9bucuma	131	19	studies	study	NNS
cord-257197-i9bucuma	131	20	that	that	WDT
cord-257197-i9bucuma	131	21	belong	belong	VBP
cord-257197-i9bucuma	131	22	to	to	IN
cord-257197-i9bucuma	131	23	the	the	DT
cord-257197-i9bucuma	131	24	same	same	JJ
cord-257197-i9bucuma	131	25	species	specie	NNS
cord-257197-i9bucuma	131	26	that	that	WDT
cord-257197-i9bucuma	131	27	is	be	VBZ
cord-257197-i9bucuma	131	28	being	be	VBG
cord-257197-i9bucuma	131	29	investigated	investigate	VBN
cord-257197-i9bucuma	131	30	in	in	IN
cord-257197-i9bucuma	131	31	vivo	vivo	NN
cord-257197-i9bucuma	131	32	.	.	.
cord-257197-i9bucuma	132	1	Surprisingly	surprisingly	RB
cord-257197-i9bucuma	132	2	,	,	,
cord-257197-i9bucuma	132	3	this	this	DT
cord-257197-i9bucuma	132	4	is	be	VBZ
cord-257197-i9bucuma	132	5	overlooked	overlook	VBN
cord-257197-i9bucuma	132	6	often	often	RB
cord-257197-i9bucuma	132	7	.	.	.
cord-257197-i9bucuma	133	1	93	93	CD
cord-257197-i9bucuma	133	2	 	 	_SP
cord-257197-i9bucuma	134	1	There	there	EX
cord-257197-i9bucuma	134	2	are	be	VBP
cord-257197-i9bucuma	134	3	hundreds	hundred	NNS
cord-257197-i9bucuma	134	4	of	of	IN
cord-257197-i9bucuma	134	5	reports	report	NNS
cord-257197-i9bucuma	134	6	on	on	IN
cord-257197-i9bucuma	134	7	the	the	DT
cord-257197-i9bucuma	134	8	toxicity	toxicity	NN
cord-257197-i9bucuma	134	9	of	of	IN
cord-257197-i9bucuma	134	10	NPs	NPs	NNPS
cord-257197-i9bucuma	134	11	in	in	IN
cord-257197-i9bucuma	134	12	vitro	vitro	NNP
cord-257197-i9bucuma	134	13	'	'	''
cord-257197-i9bucuma	134	14	or	or	CC
cord-257197-i9bucuma	134	15	'	'	''
cord-257197-i9bucuma	134	16	in	in	IN
cord-257197-i9bucuma	134	17	vivo	vivo	NN
cord-257197-i9bucuma	134	18	but	but	CC
cord-257197-i9bucuma	134	19	very	very	RB
cord-257197-i9bucuma	134	20	few	few	JJ
cord-257197-i9bucuma	134	21	recent	recent	JJ
cord-257197-i9bucuma	134	22	studies	study	NNS
cord-257197-i9bucuma	134	23	have	have	VBP
cord-257197-i9bucuma	134	24	compared	compare	VBN
cord-257197-i9bucuma	134	25	their	-PRON-	PRP$
cord-257197-i9bucuma	134	26	effects	effect	NNS
cord-257197-i9bucuma	134	27	in	in	IN
cord-257197-i9bucuma	134	28	vitro	vitro	FW
cord-257197-i9bucuma	134	29	'	'	''
cord-257197-i9bucuma	134	30	and	and	CC
cord-257197-i9bucuma	134	31	'	'	''
cord-257197-i9bucuma	134	32	in	in	IN
cord-257197-i9bucuma	134	33	vivo	vivo	NNP
cord-257197-i9bucuma	134	34	.	.	.
cord-257197-i9bucuma	135	1	Table	table	NN
cord-257197-i9bucuma	135	2	2	2	CD
cord-257197-i9bucuma	135	3	summarizes	summarize	VBZ
cord-257197-i9bucuma	135	4	the	the	DT
cord-257197-i9bucuma	135	5	studies	study	NNS
cord-257197-i9bucuma	135	6	belonging	belong	VBG
cord-257197-i9bucuma	135	7	to	to	IN
cord-257197-i9bucuma	135	8	latter	latter	JJ
cord-257197-i9bucuma	135	9	group	group	NN
cord-257197-i9bucuma	135	10	.	.	.
cord-257197-i9bucuma	135	11	 	 	_SP
cord-257197-i9bucuma	136	1	Recent	recent	JJ
cord-257197-i9bucuma	136	2	reviews	review	NNS
cord-257197-i9bucuma	136	3	by	by	IN
cord-257197-i9bucuma	136	4	Foroozandeh	Foroozandeh	NNP
cord-257197-i9bucuma	136	5	et	et	NNP
cord-257197-i9bucuma	136	6	al	al	NNP
cord-257197-i9bucuma	136	7	.	.	.
cord-257197-i9bucuma	137	1	100	100	CD
cord-257197-i9bucuma	137	2	and	and	CC
cord-257197-i9bucuma	137	3	Behzadi	Behzadi	NNP
cord-257197-i9bucuma	137	4	et	et	NNP
cord-257197-i9bucuma	137	5	al	al	NNP
cord-257197-i9bucuma	137	6	.	.	.
cord-257197-i9bucuma	138	1	101	101	CD
cord-257197-i9bucuma	138	2	discussed	discuss	VBD
cord-257197-i9bucuma	138	3	the	the	DT
cord-257197-i9bucuma	138	4	effect	effect	NN
cord-257197-i9bucuma	138	5	of	of	IN
cord-257197-i9bucuma	138	6	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	138	7	physicochemical	physicochemical	JJ
cord-257197-i9bucuma	138	8	properties	property	NNS
cord-257197-i9bucuma	138	9	such	such	JJ
cord-257197-i9bucuma	138	10	as	as	IN
cord-257197-i9bucuma	138	11	size	size	NN
cord-257197-i9bucuma	138	12	,	,	,
cord-257197-i9bucuma	138	13	shape	shape	NN
cord-257197-i9bucuma	138	14	,	,	,
cord-257197-i9bucuma	138	15	surface	surface	NN
cord-257197-i9bucuma	138	16	composition	composition	NN
cord-257197-i9bucuma	138	17	on	on	IN
cord-257197-i9bucuma	138	18	their	-PRON-	PRP$
cord-257197-i9bucuma	138	19	uptake	uptake	NN
cord-257197-i9bucuma	138	20	and	and	CC
cord-257197-i9bucuma	138	21	intracellular	intracellular	JJ
cord-257197-i9bucuma	138	22	trafficking	trafficking	NN
cord-257197-i9bucuma	138	23	.	.	.
cord-257197-i9bucuma	139	1	Unfortunately	unfortunately	RB
cord-257197-i9bucuma	139	2	,	,	,
cord-257197-i9bucuma	139	3	few	few	JJ
cord-257197-i9bucuma	139	4	articles	article	NNS
cord-257197-i9bucuma	139	5	discuss	discuss	VBP
cord-257197-i9bucuma	139	6	the	the	DT
cord-257197-i9bucuma	139	7	effect	effect	NN
cord-257197-i9bucuma	139	8	of	of	IN
cord-257197-i9bucuma	139	9	experimental	experimental	JJ
cord-257197-i9bucuma	139	10	parameters	parameter	NNS
cord-257197-i9bucuma	139	11	on	on	IN
cord-257197-i9bucuma	139	12	cellular	cellular	JJ
cord-257197-i9bucuma	139	13	uptake	uptake	NN
cord-257197-i9bucuma	139	14	.	.	.
cord-257197-i9bucuma	140	1	In	in	IN
cord-257197-i9bucuma	140	2	the	the	DT
cord-257197-i9bucuma	140	3	following	follow	VBG
cord-257197-i9bucuma	140	4	section	section	NN
cord-257197-i9bucuma	140	5	the	the	DT
cord-257197-i9bucuma	140	6	importance	importance	NN
cord-257197-i9bucuma	140	7	of	of	IN
cord-257197-i9bucuma	140	8	carefully	carefully	RB
cord-257197-i9bucuma	140	9	selecting	select	VBG
cord-257197-i9bucuma	140	10	cell	cell	NN
cord-257197-i9bucuma	140	11	lines	line	NNS
cord-257197-i9bucuma	140	12	,	,	,
cord-257197-i9bucuma	140	13	determining	determine	VBG
cord-257197-i9bucuma	140	14	effect	effect	NN
cord-257197-i9bucuma	140	15	of	of	IN
cord-257197-i9bucuma	140	16	dosage	dosage	NN
cord-257197-i9bucuma	140	17	,	,	,
cord-257197-i9bucuma	140	18	time	time	NN
cord-257197-i9bucuma	140	19	and	and	CC
cord-257197-i9bucuma	140	20	media	medium	NNS
cord-257197-i9bucuma	140	21	type	type	NN
cord-257197-i9bucuma	140	22	in	in	IN
cord-257197-i9bucuma	140	23	understanding	understand	VBG
cord-257197-i9bucuma	140	24	NP	NP	NNP
cord-257197-i9bucuma	140	25	interactions	interaction	NNS
cord-257197-i9bucuma	140	26	will	will	MD
cord-257197-i9bucuma	140	27	be	be	VB
cord-257197-i9bucuma	140	28	J	J	NNP
cord-257197-i9bucuma	140	29	o	o	NN
cord-257197-i9bucuma	140	30	u	u	NN
cord-257197-i9bucuma	140	31	r	r	NN
cord-257197-i9bucuma	140	32	n	n	NN
cord-257197-i9bucuma	140	33	a	a	DT
cord-257197-i9bucuma	140	34	l	l	NN
cord-257197-i9bucuma	140	35	P	p	NN
cord-257197-i9bucuma	140	36	r	r	NN
cord-257197-i9bucuma	140	37	e	e	NN
cord-257197-i9bucuma	140	38	-p	-p	NN
cord-257197-i9bucuma	141	1	r	r	LS
cord-257197-i9bucuma	142	1	o	o	UH
cord-257197-i9bucuma	142	2	o	o	NN
cord-257197-i9bucuma	142	3	f	f	NN
cord-257197-i9bucuma	142	4	discussed	discuss	VBD
cord-257197-i9bucuma	142	5	.	.	.
cord-257197-i9bucuma	143	1	We	-PRON-	PRP
cord-257197-i9bucuma	143	2	also	also	RB
cord-257197-i9bucuma	143	3	review	review	VBP
cord-257197-i9bucuma	143	4	recent	recent	JJ
cord-257197-i9bucuma	143	5	studies	study	NNS
cord-257197-i9bucuma	143	6	that	that	WDT
cord-257197-i9bucuma	143	7	explore	explore	VBP
cord-257197-i9bucuma	143	8	cellular	cellular	JJ
cord-257197-i9bucuma	143	9	uptake	uptake	NN
cord-257197-i9bucuma	143	10	routes	route	NNS
cord-257197-i9bucuma	143	11	,	,	,
cord-257197-i9bucuma	143	12	immune	immune	JJ
cord-257197-i9bucuma	143	13	responses	response	NNS
cord-257197-i9bucuma	143	14	and	and	CC
cord-257197-i9bucuma	143	15	toxicity	toxicity	NN
cord-257197-i9bucuma	143	16	induced	induce	VBN
cord-257197-i9bucuma	143	17	by	by	IN
cord-257197-i9bucuma	143	18	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	143	19	and	and	CC
cord-257197-i9bucuma	143	20	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	143	21	with	with	IN
cord-257197-i9bucuma	143	22	different	different	JJ
cord-257197-i9bucuma	143	23	surface	surface	NN
cord-257197-i9bucuma	143	24	compositions	composition	NNS
cord-257197-i9bucuma	143	25	.	.	.
cord-257197-i9bucuma	144	1	A.	a.	JJ
cord-257197-i9bucuma	144	2	Influence	influence	NN
cord-257197-i9bucuma	144	3	of	of	IN
cord-257197-i9bucuma	144	4	various	various	JJ
cord-257197-i9bucuma	144	5	experimental	experimental	JJ
cord-257197-i9bucuma	144	6	parameters	parameter	NNS
cord-257197-i9bucuma	144	7	Cell	cell	NN
cord-257197-i9bucuma	144	8	lines	line	NNS
cord-257197-i9bucuma	144	9	used	use	VBN
cord-257197-i9bucuma	144	10	to	to	TO
cord-257197-i9bucuma	144	11	study	study	VB
cord-257197-i9bucuma	144	12	NPs	NPs	NNP
cord-257197-i9bucuma	144	13	are	be	VBP
cord-257197-i9bucuma	144	14	commonly	commonly	RB
cord-257197-i9bucuma	144	15	selected	select	VBN
cord-257197-i9bucuma	144	16	based	base	VBN
cord-257197-i9bucuma	144	17	on	on	IN
cord-257197-i9bucuma	144	18	availability	availability	NN
cord-257197-i9bucuma	144	19	;	;	:
cord-257197-i9bucuma	144	20	they	-PRON-	PRP
cord-257197-i9bucuma	144	21	should	should	MD
cord-257197-i9bucuma	144	22	be	be	VB
cord-257197-i9bucuma	144	23	chosen	choose	VBN
cord-257197-i9bucuma	144	24	based	base	VBN
cord-257197-i9bucuma	144	25	on	on	IN
cord-257197-i9bucuma	144	26	the	the	DT
cord-257197-i9bucuma	144	27	applications	application	NNS
cord-257197-i9bucuma	144	28	of	of	IN
cord-257197-i9bucuma	144	29	NPs	NPs	NNPS
cord-257197-i9bucuma	144	30	and	and	CC
cord-257197-i9bucuma	144	31	the	the	DT
cord-257197-i9bucuma	144	32	expected	expect	VBN
cord-257197-i9bucuma	144	33	in	in	IN
cord-257197-i9bucuma	144	34	vivo	vivo	NN
cord-257197-i9bucuma	144	35	exposure	exposure	NN
cord-257197-i9bucuma	144	36	.	.	.
cord-257197-i9bucuma	145	1	102	102	CD
cord-257197-i9bucuma	145	2	Several	several	JJ
cord-257197-i9bucuma	145	3	studies	study	NNS
cord-257197-i9bucuma	145	4	have	have	VBP
cord-257197-i9bucuma	145	5	shown	show	VBN
cord-257197-i9bucuma	145	6	that	that	IN
cord-257197-i9bucuma	145	7	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	145	8	uptake	uptake	NN
cord-257197-i9bucuma	145	9	and	and	CC
cord-257197-i9bucuma	145	10	toxicity	toxicity	NN
cord-257197-i9bucuma	145	11	profiles	profile	NNS
cord-257197-i9bucuma	145	12	vary	vary	VBP
cord-257197-i9bucuma	145	13	between	between	IN
cord-257197-i9bucuma	145	14	cell	cell	NN
cord-257197-i9bucuma	145	15	lines	line	NNS
cord-257197-i9bucuma	145	16	,	,	,
cord-257197-i9bucuma	145	17	cell	cell	NN
cord-257197-i9bucuma	145	18	sub	sub	NN
cord-257197-i9bucuma	145	19	-	-	NNS
cord-257197-i9bucuma	145	20	types	type	NNS
cord-257197-i9bucuma	145	21	and	and	CC
cord-257197-i9bucuma	145	22	to	to	IN
cord-257197-i9bucuma	145	23	some	some	DT
cord-257197-i9bucuma	145	24	extent	extent	NN
cord-257197-i9bucuma	145	25	between	between	IN
cord-257197-i9bucuma	145	26	species	specie	NNS
cord-257197-i9bucuma	145	27	.	.	.
cord-257197-i9bucuma	146	1	[	[	-LRB-
cord-257197-i9bucuma	146	2	102	102	CD
cord-257197-i9bucuma	146	3	]	]	-RRB-
cord-257197-i9bucuma	146	4	[	[	-LRB-
cord-257197-i9bucuma	146	5	103	103	CD
cord-257197-i9bucuma	146	6	]	]	-RRB-
cord-257197-i9bucuma	146	7	[	[	-LRB-
cord-257197-i9bucuma	146	8	104	104	CD
cord-257197-i9bucuma	146	9	]	]	-RRB-
cord-257197-i9bucuma	146	10	[	[	-LRB-
cord-257197-i9bucuma	146	11	105	105	CD
cord-257197-i9bucuma	146	12	]	]	-RRB-
cord-257197-i9bucuma	146	13	[	[	-LRB-
cord-257197-i9bucuma	146	14	106	106	CD
cord-257197-i9bucuma	146	15	]	]	-RRB-
cord-257197-i9bucuma	147	1	The	the	DT
cord-257197-i9bucuma	147	2	uptake	uptake	NN
cord-257197-i9bucuma	147	3	of	of	IN
cord-257197-i9bucuma	147	4	NPs	NPs	NNPS
cord-257197-i9bucuma	147	5	is	be	VBZ
cord-257197-i9bucuma	147	6	also	also	RB
cord-257197-i9bucuma	147	7	dependent	dependent	JJ
cord-257197-i9bucuma	147	8	on	on	IN
cord-257197-i9bucuma	147	9	cell	cell	NN
cord-257197-i9bucuma	147	10	-	-	HYPH
cord-257197-i9bucuma	147	11	specific	specific	JJ
cord-257197-i9bucuma	147	12	functions	function	NNS
cord-257197-i9bucuma	147	13	.	.	.
cord-257197-i9bucuma	148	1	107	107	CD
cord-257197-i9bucuma	149	1	Although	although	IN
cord-257197-i9bucuma	149	2	immortalized	immortalize	VBN
cord-257197-i9bucuma	149	3	cell	cell	NN
cord-257197-i9bucuma	149	4	lines	line	NNS
cord-257197-i9bucuma	149	5	are	be	VBP
cord-257197-i9bucuma	149	6	easier	easy	JJR
cord-257197-i9bucuma	149	7	to	to	TO
cord-257197-i9bucuma	149	8	maintain	maintain	VB
cord-257197-i9bucuma	149	9	,	,	,
cord-257197-i9bucuma	149	10	readily	readily	RB
cord-257197-i9bucuma	149	11	accessible	accessible	JJ
cord-257197-i9bucuma	149	12	and	and	CC
cord-257197-i9bucuma	149	13	widely	widely	RB
cord-257197-i9bucuma	149	14	studied	study	VBN
cord-257197-i9bucuma	149	15	,	,	,
cord-257197-i9bucuma	149	16	they	-PRON-	PRP
cord-257197-i9bucuma	149	17	differ	differ	VBP
cord-257197-i9bucuma	149	18	from	from	IN
cord-257197-i9bucuma	149	19	cells	cell	NNS
cord-257197-i9bucuma	149	20	in	in	IN
cord-257197-i9bucuma	149	21	vivo	vivo	NN
cord-257197-i9bucuma	149	22	due	due	IN
cord-257197-i9bucuma	149	23	to	to	IN
cord-257197-i9bucuma	149	24	repeated	repeat	VBN
cord-257197-i9bucuma	149	25	in	in	IN
cord-257197-i9bucuma	149	26	vitro	vitro	FW
cord-257197-i9bucuma	149	27	manipulations	manipulation	NNS
cord-257197-i9bucuma	149	28	and	and	CC
cord-257197-i9bucuma	149	29	the	the	DT
cord-257197-i9bucuma	149	30	initial	initial	JJ
cord-257197-i9bucuma	149	31	immortalization	immortalization	NN
cord-257197-i9bucuma	149	32	itself	-PRON-	PRP
cord-257197-i9bucuma	149	33	.	.	.
cord-257197-i9bucuma	150	1	102	102	CD
cord-257197-i9bucuma	150	2	Joris	Joris	NNP
cord-257197-i9bucuma	150	3	et	et	NNP
cord-257197-i9bucuma	150	4	al	al	NNP
cord-257197-i9bucuma	150	5	.	.	.
cord-257197-i9bucuma	151	1	102	102	CD
cord-257197-i9bucuma	151	2	facilitates	facilitate	VBZ
cord-257197-i9bucuma	151	3	co	co	NN
cord-257197-i9bucuma	151	4	-	-	NN
cord-257197-i9bucuma	151	5	culturing	culturing	NN
cord-257197-i9bucuma	151	6	of	of	IN
cord-257197-i9bucuma	151	7	multiple	multiple	JJ
cord-257197-i9bucuma	151	8	cell	cell	NN
cord-257197-i9bucuma	151	9	types	type	NNS
cord-257197-i9bucuma	151	10	simultaneously	simultaneously	RB
cord-257197-i9bucuma	151	11	,	,	,
cord-257197-i9bucuma	151	12	to	to	TO
cord-257197-i9bucuma	151	13	evaluate	evaluate	VB
cord-257197-i9bucuma	151	14	the	the	DT
cord-257197-i9bucuma	151	15	effect	effect	NN
cord-257197-i9bucuma	151	16	of	of	IN
cord-257197-i9bucuma	151	17	NPs	NPs	NNP
cord-257197-i9bucuma	151	18	treatment	treatment	NN
cord-257197-i9bucuma	151	19	on	on	IN
cord-257197-i9bucuma	151	20	the	the	DT
cord-257197-i9bucuma	151	21	crosstalk	crosstalk	NN
cord-257197-i9bucuma	151	22	between	between	IN
cord-257197-i9bucuma	151	23	the	the	DT
cord-257197-i9bucuma	151	24	cell	cell	NN
cord-257197-i9bucuma	151	25	types	type	NNS
cord-257197-i9bucuma	151	26	or	or	CC
cord-257197-i9bucuma	151	27	to	to	TO
cord-257197-i9bucuma	151	28	study	study	VB
cord-257197-i9bucuma	151	29	transcytosis	transcytosis	NNP
cord-257197-i9bucuma	151	30	.	.	.
cord-257197-i9bucuma	152	1	[	[	-LRB-
cord-257197-i9bucuma	152	2	110	110	CD
cord-257197-i9bucuma	152	3	]	]	-RRB-
cord-257197-i9bucuma	152	4	[	[	-LRB-
cord-257197-i9bucuma	152	5	111	111	CD
cord-257197-i9bucuma	152	6	]	]	-RRB-
cord-257197-i9bucuma	152	7	[	[	-LRB-
cord-257197-i9bucuma	152	8	112	112	CD
cord-257197-i9bucuma	152	9	]	]	-RRB-
cord-257197-i9bucuma	152	10	Three	three	CD
cord-257197-i9bucuma	152	11	-	-	HYPH
cord-257197-i9bucuma	152	12	D	d	NN
cord-257197-i9bucuma	152	13	cell	cell	NN
cord-257197-i9bucuma	152	14	cultures	culture	NNS
cord-257197-i9bucuma	152	15	that	that	WDT
cord-257197-i9bucuma	152	16	make	make	VBP
cord-257197-i9bucuma	152	17	use	use	NN
cord-257197-i9bucuma	152	18	of	of	IN
cord-257197-i9bucuma	152	19	a	a	DT
cord-257197-i9bucuma	152	20	scaffold	scaffold	NN
cord-257197-i9bucuma	152	21	increase	increase	VB
cord-257197-i9bucuma	152	22	the	the	DT
cord-257197-i9bucuma	152	23	surface	surface	NN
cord-257197-i9bucuma	152	24	area	area	NN
cord-257197-i9bucuma	152	25	of	of	IN
cord-257197-i9bucuma	152	26	exposure	exposure	NN
cord-257197-i9bucuma	152	27	,	,	,
cord-257197-i9bucuma	152	28	while	while	IN
cord-257197-i9bucuma	152	29	only	only	RB
cord-257197-i9bucuma	152	30	~50	~50	XX
cord-257197-i9bucuma	152	31	%	%	NN
cord-257197-i9bucuma	152	32	area	area	NN
cord-257197-i9bucuma	152	33	is	be	VBZ
cord-257197-i9bucuma	152	34	available	available	JJ
cord-257197-i9bucuma	152	35	in	in	IN
cord-257197-i9bucuma	152	36	a	a	DT
cord-257197-i9bucuma	152	37	2D	2d	JJ
cord-257197-i9bucuma	152	38	cell	cell	NN
cord-257197-i9bucuma	152	39	culture	culture	NN
cord-257197-i9bucuma	152	40	.	.	.
cord-257197-i9bucuma	153	1	The	the	DT
cord-257197-i9bucuma	153	2	MD1-MB231	MD1-MB231	NNP
cord-257197-i9bucuma	153	3	breast	breast	NN
cord-257197-i9bucuma	153	4	cancer	cancer	NN
cord-257197-i9bucuma	153	5	cells	cell	NNS
cord-257197-i9bucuma	153	6	in	in	IN
cord-257197-i9bucuma	153	7	2D	2d	NN
cord-257197-i9bucuma	153	8	culture	culture	NN
cord-257197-i9bucuma	153	9	,	,	,
cord-257197-i9bucuma	153	10	in	in	IN
cord-257197-i9bucuma	153	11	comparison	comparison	NN
cord-257197-i9bucuma	153	12	to	to	IN
cord-257197-i9bucuma	153	13	their	-PRON-	PRP$
cord-257197-i9bucuma	153	14	3D	3d	JJ
cord-257197-i9bucuma	153	15	counterpart	counterpart	NN
cord-257197-i9bucuma	153	16	,	,	,
cord-257197-i9bucuma	153	17	had	have	VBD
cord-257197-i9bucuma	153	18	increased	increase	VBN
cord-257197-i9bucuma	153	19	viability	viability	NN
cord-257197-i9bucuma	153	20	and	and	CC
cord-257197-i9bucuma	153	21	showed	show	VBD
cord-257197-i9bucuma	153	22	a	a	DT
cord-257197-i9bucuma	153	23	lesser	less	JJR
cord-257197-i9bucuma	153	24	change	change	NN
cord-257197-i9bucuma	153	25	in	in	IN
cord-257197-i9bucuma	153	26	the	the	DT
cord-257197-i9bucuma	153	27	cytoplasmic	cytoplasmic	JJ
cord-257197-i9bucuma	153	28	actin	actin	NN
cord-257197-i9bucuma	153	29	network	network	NN
cord-257197-i9bucuma	153	30	that	that	WDT
cord-257197-i9bucuma	153	31	plays	play	VBZ
cord-257197-i9bucuma	153	32	a	a	DT
cord-257197-i9bucuma	153	33	major	major	JJ
cord-257197-i9bucuma	153	34	role	role	NN
cord-257197-i9bucuma	153	35	in	in	IN
cord-257197-i9bucuma	153	36	intracellular	intracellular	JJ
cord-257197-i9bucuma	153	37	processes	process	NNS
cord-257197-i9bucuma	153	38	.	.	.
cord-257197-i9bucuma	154	1	103	103	CD
cord-257197-i9bucuma	155	1	Thus	thus	RB
cord-257197-i9bucuma	155	2	,	,	,
cord-257197-i9bucuma	155	3	the	the	DT
cord-257197-i9bucuma	155	4	toxicity	toxicity	NN
cord-257197-i9bucuma	155	5	of	of	IN
cord-257197-i9bucuma	155	6	the	the	DT
cord-257197-i9bucuma	155	7	NPs	NPs	NNPS
cord-257197-i9bucuma	155	8	could	could	MD
cord-257197-i9bucuma	155	9	be	be	VB
cord-257197-i9bucuma	155	10	underestimated	underestimate	VBN
cord-257197-i9bucuma	155	11	by	by	IN
cord-257197-i9bucuma	155	12	testing	test	VBG
cord-257197-i9bucuma	155	13	their	-PRON-	PRP$
cord-257197-i9bucuma	155	14	effect	effect	NN
cord-257197-i9bucuma	155	15	in	in	IN
cord-257197-i9bucuma	155	16	just	just	RB
cord-257197-i9bucuma	155	17	2D	2d	JJ
cord-257197-i9bucuma	155	18	cell	cell	NN
cord-257197-i9bucuma	155	19	cultures	culture	NNS
cord-257197-i9bucuma	155	20	and	and	CC
cord-257197-i9bucuma	155	21	immortalized	immortalize	VBN
cord-257197-i9bucuma	155	22	cell	cell	NN
cord-257197-i9bucuma	155	23	lines	line	NNS
cord-257197-i9bucuma	155	24	.	.	.
cord-257197-i9bucuma	156	1	In	in	IN
cord-257197-i9bucuma	156	2	vivo	vivo	NN
cord-257197-i9bucuma	156	3	,	,	,
cord-257197-i9bucuma	156	4	NPs	NPs	NNP
cord-257197-i9bucuma	156	5	and	and	CC
cord-257197-i9bucuma	156	6	drugs	drug	NNS
cord-257197-i9bucuma	156	7	have	have	VBP
cord-257197-i9bucuma	156	8	a	a	DT
cord-257197-i9bucuma	156	9	tendency	tendency	NN
cord-257197-i9bucuma	156	10	to	to	TO
cord-257197-i9bucuma	156	11	accumulate	accumulate	VB
cord-257197-i9bucuma	156	12	in	in	IN
cord-257197-i9bucuma	156	13	the	the	DT
cord-257197-i9bucuma	156	14	liver	liver	NN
cord-257197-i9bucuma	156	15	generally	generally	RB
cord-257197-i9bucuma	156	16	,	,	,
cord-257197-i9bucuma	156	17	which	which	WDT
cord-257197-i9bucuma	156	18	clears	clear	VBZ
cord-257197-i9bucuma	156	19	foreign	foreign	JJ
cord-257197-i9bucuma	156	20	materials	material	NNS
cord-257197-i9bucuma	156	21	and	and	CC
cord-257197-i9bucuma	156	22	thus	thus	RB
cord-257197-i9bucuma	156	23	,	,	,
cord-257197-i9bucuma	156	24	the	the	DT
cord-257197-i9bucuma	156	25	liver	liver	NN
cord-257197-i9bucuma	156	26	is	be	VBZ
cord-257197-i9bucuma	156	27	an	an	DT
cord-257197-i9bucuma	156	28	important	important	JJ
cord-257197-i9bucuma	156	29	tissue	tissue	NN
cord-257197-i9bucuma	156	30	to	to	TO
cord-257197-i9bucuma	156	31	consider	consider	VB
cord-257197-i9bucuma	156	32	for	for	IN
cord-257197-i9bucuma	156	33	studying	study	VBG
cord-257197-i9bucuma	156	34	NPs	NPs	NNP
cord-257197-i9bucuma	156	35	.	.	.
cord-257197-i9bucuma	157	1	The	the	DT
cord-257197-i9bucuma	157	2	sandwich	sandwich	NN
cord-257197-i9bucuma	157	3	hepatocyte	hepatocyte	NN
cord-257197-i9bucuma	157	4	culture	culture	NN
cord-257197-i9bucuma	157	5	model	model	NN
cord-257197-i9bucuma	157	6	uses	use	VBZ
cord-257197-i9bucuma	157	7	primary	primary	JJ
cord-257197-i9bucuma	157	8	hepatocytes	hepatocyte	NNS
cord-257197-i9bucuma	157	9	,	,	,
cord-257197-i9bucuma	157	10	grown	grow	VBN
cord-257197-i9bucuma	157	11	between	between	IN
cord-257197-i9bucuma	157	12	two	two	CD
cord-257197-i9bucuma	157	13	layers	layer	NNS
cord-257197-i9bucuma	157	14	of	of	IN
cord-257197-i9bucuma	157	15	collagen	collagen	NN
cord-257197-i9bucuma	157	16	that	that	WDT
cord-257197-i9bucuma	157	17	keeps	keep	VBZ
cord-257197-i9bucuma	157	18	them	-PRON-	PRP
cord-257197-i9bucuma	157	19	competent	competent	JJ
cord-257197-i9bucuma	157	20	and	and	CC
cord-257197-i9bucuma	157	21	polarized	polarized	JJ
cord-257197-i9bucuma	157	22	with	with	IN
cord-257197-i9bucuma	157	23	functional	functional	JJ
cord-257197-i9bucuma	157	24	J	J	NNP
cord-257197-i9bucuma	157	25	o	o	NN
cord-257197-i9bucuma	157	26	u	u	NN
cord-257197-i9bucuma	157	27	r	r	NN
cord-257197-i9bucuma	157	28	n	n	NN
cord-257197-i9bucuma	157	29	a	a	DT
cord-257197-i9bucuma	157	30	l	l	NN
cord-257197-i9bucuma	157	31	P	p	NN
cord-257197-i9bucuma	157	32	r	r	NN
cord-257197-i9bucuma	157	33	e	e	NN
cord-257197-i9bucuma	157	34	-p	-p	NN
cord-257197-i9bucuma	157	35	r	r	NN
cord-257197-i9bucuma	157	36	o	o	NN
cord-257197-i9bucuma	157	37	o	o	NN
cord-257197-i9bucuma	157	38	f	f	NN
cord-257197-i9bucuma	157	39	bile	bile	NN
cord-257197-i9bucuma	157	40	networks	network	NNS
cord-257197-i9bucuma	157	41	and	and	CC
cord-257197-i9bucuma	157	42	helps	help	VBZ
cord-257197-i9bucuma	157	43	to	to	TO
cord-257197-i9bucuma	157	44	assess	assess	VB
cord-257197-i9bucuma	157	45	the	the	DT
cord-257197-i9bucuma	157	46	hepatotoxicity	hepatotoxicity	NN
cord-257197-i9bucuma	157	47	of	of	IN
cord-257197-i9bucuma	157	48	drugs	drug	NNS
cord-257197-i9bucuma	157	49	and	and	CC
cord-257197-i9bucuma	157	50	NPs	NPs	NNP
cord-257197-i9bucuma	157	51	accurately	accurately	RB
cord-257197-i9bucuma	157	52	.	.	.
cord-257197-i9bucuma	158	1	113	113	CD
cord-257197-i9bucuma	159	1	While	while	IN
cord-257197-i9bucuma	159	2	3-D	3-d	JJ
cord-257197-i9bucuma	159	3	cultures	culture	NNS
cord-257197-i9bucuma	159	4	mimic	mimic	VBP
cord-257197-i9bucuma	159	5	the	the	DT
cord-257197-i9bucuma	159	6	in	in	IN
cord-257197-i9bucuma	159	7	vivo	vivo	NN
cord-257197-i9bucuma	159	8	environment	environment	NN
cord-257197-i9bucuma	159	9	more	more	RBR
cord-257197-i9bucuma	159	10	closely	closely	RB
cord-257197-i9bucuma	159	11	not	not	RB
cord-257197-i9bucuma	159	12	all	all	DT
cord-257197-i9bucuma	159	13	labs	lab	NNS
cord-257197-i9bucuma	159	14	have	have	VBP
cord-257197-i9bucuma	159	15	transitioned	transition	VBN
cord-257197-i9bucuma	159	16	to	to	IN
cord-257197-i9bucuma	159	17	this	this	DT
cord-257197-i9bucuma	159	18	approach	approach	NN
cord-257197-i9bucuma	159	19	.	.	.
cord-257197-i9bucuma	160	1	Traditional	traditional	JJ
cord-257197-i9bucuma	160	2	2D	2d	NN
cord-257197-i9bucuma	160	3	cultures	culture	NNS
cord-257197-i9bucuma	160	4	still	still	RB
cord-257197-i9bucuma	160	5	predominate	predominate	VBP
cord-257197-i9bucuma	160	6	in	in	IN
cord-257197-i9bucuma	160	7	the	the	DT
cord-257197-i9bucuma	160	8	current	current	JJ
cord-257197-i9bucuma	160	9	literature	literature	NN
cord-257197-i9bucuma	160	10	.	.	.
cord-257197-i9bucuma	161	1	Cell	cell	NN
cord-257197-i9bucuma	161	2	culture	culture	NN
cord-257197-i9bucuma	161	3	media	medium	NNS
cord-257197-i9bucuma	161	4	composition	composition	NN
cord-257197-i9bucuma	161	5	varies	vary	VBZ
cord-257197-i9bucuma	161	6	depending	depend	VBG
cord-257197-i9bucuma	161	7	upon	upon	IN
cord-257197-i9bucuma	161	8	the	the	DT
cord-257197-i9bucuma	161	9	requirements	requirement	NNS
cord-257197-i9bucuma	161	10	of	of	IN
cord-257197-i9bucuma	161	11	each	each	DT
cord-257197-i9bucuma	161	12	cell	cell	NN
cord-257197-i9bucuma	161	13	line	line	NN
cord-257197-i9bucuma	161	14	.	.	.
cord-257197-i9bucuma	162	1	observed	observe	VBD
cord-257197-i9bucuma	162	2	a	a	DT
cord-257197-i9bucuma	162	3	similar	similar	JJ
cord-257197-i9bucuma	162	4	effect	effect	NN
cord-257197-i9bucuma	162	5	where	where	WRB
cord-257197-i9bucuma	162	6	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	162	7	pre	pre	VB
cord-257197-i9bucuma	162	8	-	-	VBN
cord-257197-i9bucuma	162	9	exposed	expose	VBN
cord-257197-i9bucuma	162	10	to	to	IN
cord-257197-i9bucuma	162	11	protein	protein	NN
cord-257197-i9bucuma	162	12	poor	poor	JJ
cord-257197-i9bucuma	162	13	medium	medium	NN
cord-257197-i9bucuma	162	14	had	have	VBD
cord-257197-i9bucuma	162	15	a	a	DT
cord-257197-i9bucuma	162	16	higher	high	JJR
cord-257197-i9bucuma	162	17	tendency	tendency	NN
cord-257197-i9bucuma	162	18	to	to	TO
cord-257197-i9bucuma	162	19	aggregate	aggregate	VB
cord-257197-i9bucuma	162	20	than	than	IN
cord-257197-i9bucuma	162	21	in	in	IN
cord-257197-i9bucuma	162	22	protein	protein	JJ
cord-257197-i9bucuma	162	23	rich	rich	JJ
cord-257197-i9bucuma	162	24	medium	medium	NN
cord-257197-i9bucuma	162	25	.	.	.
cord-257197-i9bucuma	163	1	Interestingly	interestingly	RB
cord-257197-i9bucuma	163	2	,	,	,
cord-257197-i9bucuma	163	3	15	15	CD
cord-257197-i9bucuma	163	4	nm	nm	IN
cord-257197-i9bucuma	163	5	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	163	6	exerted	exert	VBD
cord-257197-i9bucuma	163	7	more	more	RBR
cord-257197-i9bucuma	163	8	adverse	adverse	JJ
cord-257197-i9bucuma	163	9	effects	effect	NNS
cord-257197-i9bucuma	163	10	on	on	IN
cord-257197-i9bucuma	163	11	cells	cell	NNS
cord-257197-i9bucuma	163	12	in	in	IN
cord-257197-i9bucuma	163	13	RPMI	RPMI	NNP
cord-257197-i9bucuma	163	14	in	in	IN
cord-257197-i9bucuma	163	15	comparison	comparison	NN
cord-257197-i9bucuma	163	16	to	to	IN
cord-257197-i9bucuma	163	17	DMEM	DMEM	NNP
cord-257197-i9bucuma	163	18	.	.	.
cord-257197-i9bucuma	164	1	Hence	hence	RB
cord-257197-i9bucuma	164	2	,	,	,
cord-257197-i9bucuma	164	3	while	while	IN
cord-257197-i9bucuma	164	4	designing	design	VBG
cord-257197-i9bucuma	164	5	and	and	CC
cord-257197-i9bucuma	164	6	implementing	implement	VBG
cord-257197-i9bucuma	164	7	studies	study	NNS
cord-257197-i9bucuma	164	8	,	,	,
cord-257197-i9bucuma	164	9	we	-PRON-	PRP
cord-257197-i9bucuma	164	10	should	should	MD
cord-257197-i9bucuma	164	11	consider	consider	VB
cord-257197-i9bucuma	164	12	the	the	DT
cord-257197-i9bucuma	164	13	choice	choice	NN
cord-257197-i9bucuma	164	14	of	of	IN
cord-257197-i9bucuma	164	15	cell	cell	NN
cord-257197-i9bucuma	164	16	culture	culture	NN
cord-257197-i9bucuma	164	17	media	medium	NNS
cord-257197-i9bucuma	164	18	which	which	WDT
cord-257197-i9bucuma	164	19	is	be	VBZ
cord-257197-i9bucuma	164	20	crucial	crucial	JJ
cord-257197-i9bucuma	164	21	.	.	.
cord-257197-i9bucuma	165	1	117	117	CD
cord-257197-i9bucuma	166	1	Another	another	DT
cord-257197-i9bucuma	166	2	non	non	JJ
cord-257197-i9bucuma	166	3	-	-	JJ
cord-257197-i9bucuma	166	4	trivial	trivial	JJ
cord-257197-i9bucuma	166	5	factor	factor	NN
cord-257197-i9bucuma	166	6	to	to	TO
cord-257197-i9bucuma	166	7	be	be	VB
cord-257197-i9bucuma	166	8	considered	consider	VBN
cord-257197-i9bucuma	166	9	is	be	VBZ
cord-257197-i9bucuma	166	10	the	the	DT
cord-257197-i9bucuma	166	11	method	method	NN
cord-257197-i9bucuma	166	12	by	by	IN
cord-257197-i9bucuma	166	13	which	which	WDT
cord-257197-i9bucuma	166	14	NPs	NPs	NNP
cord-257197-i9bucuma	166	15	are	be	VBP
cord-257197-i9bucuma	166	16	administered	administer	VBN
cord-257197-i9bucuma	166	17	as	as	IN
cord-257197-i9bucuma	166	18	documented	document	VBN
cord-257197-i9bucuma	166	19	by	by	IN
cord-257197-i9bucuma	166	20	Moore	Moore	NNP
cord-257197-i9bucuma	166	21	et	et	NNP
cord-257197-i9bucuma	166	22	al	al	NNP
cord-257197-i9bucuma	166	23	.	.	.
cord-257197-i9bucuma	167	1	107	107	CD
cord-257197-i9bucuma	168	1	When	when	WRB
cord-257197-i9bucuma	168	2	poly(vinylpyrrolidone	poly(vinylpyrrolidone	NN
cord-257197-i9bucuma	168	3	)	)	-RRB-
cord-257197-i9bucuma	168	4	(	(	-LRB-
cord-257197-i9bucuma	168	5	PVP	PVP	NNP
cord-257197-i9bucuma	168	6	)	)	-RRB-
cord-257197-i9bucuma	168	7	coated	coat	VBD
cord-257197-i9bucuma	168	8	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	168	9	were	be	VBD
cord-257197-i9bucuma	168	10	administered	administer	VBN
cord-257197-i9bucuma	168	11	as	as	IN
cord-257197-i9bucuma	168	12	a	a	DT
cord-257197-i9bucuma	168	13	concentrated	concentrated	JJ
cord-257197-i9bucuma	168	14	bolus	bolus	NN
cord-257197-i9bucuma	168	15	directly	directly	RB
cord-257197-i9bucuma	168	16	to	to	IN
cord-257197-i9bucuma	168	17	J774A.1	J774A.1	NNP
cord-257197-i9bucuma	168	18	mouse	mouse	NN
cord-257197-i9bucuma	168	19	macrophages	macrophage	NNS
cord-257197-i9bucuma	168	20	,	,	,
cord-257197-i9bucuma	168	21	the	the	DT
cord-257197-i9bucuma	168	22	protein	protein	NN
cord-257197-i9bucuma	168	23	corona	corona	NN
cord-257197-i9bucuma	168	24	formation	formation	NN
cord-257197-i9bucuma	168	25	was	be	VBD
cord-257197-i9bucuma	168	26	2-fold	2-fold	RB
cord-257197-i9bucuma	168	27	higher	high	JJR
cord-257197-i9bucuma	168	28	than	than	IN
cord-257197-i9bucuma	168	29	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	168	30	pre	pre	JJ
cord-257197-i9bucuma	168	31	-	-	JJ
cord-257197-i9bucuma	168	32	mixed	mixed	JJ
cord-257197-i9bucuma	168	33	with	with	IN
cord-257197-i9bucuma	168	34	media	medium	NNS
cord-257197-i9bucuma	168	35	.	.	.
cord-257197-i9bucuma	169	1	The	the	DT
cord-257197-i9bucuma	169	2	macrophages	macrophage	NNS
cord-257197-i9bucuma	169	3	also	also	RB
cord-257197-i9bucuma	169	4	phagocytosed	phagocytose	VBD
cord-257197-i9bucuma	169	5	more	more	RBR
cord-257197-i9bucuma	169	6	AuNPs	aunps	RBR
cord-257197-i9bucuma	169	7	administered	administer	VBN
cord-257197-i9bucuma	169	8	as	as	IN
cord-257197-i9bucuma	169	9	a	a	DT
cord-257197-i9bucuma	169	10	concentrated	concentrated	JJ
cord-257197-i9bucuma	169	11	dose	dose	NN
cord-257197-i9bucuma	169	12	in	in	IN
cord-257197-i9bucuma	169	13	comparison	comparison	NN
cord-257197-i9bucuma	169	14	to	to	IN
cord-257197-i9bucuma	169	15	the	the	DT
cord-257197-i9bucuma	169	16	pre	pre	JJ
cord-257197-i9bucuma	169	17	-	-	JJ
cord-257197-i9bucuma	169	18	mixed	mixed	JJ
cord-257197-i9bucuma	169	19	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	169	20	.	.	.
cord-257197-i9bucuma	170	1	This	this	DT
cord-257197-i9bucuma	170	2	study	study	NN
cord-257197-i9bucuma	170	3	emphasizes	emphasize	VBZ
cord-257197-i9bucuma	170	4	how	how	WRB
cord-257197-i9bucuma	170	5	a	a	DT
cord-257197-i9bucuma	170	6	minor	minor	JJ
cord-257197-i9bucuma	170	7	detail	detail	NN
cord-257197-i9bucuma	170	8	such	such	JJ
cord-257197-i9bucuma	170	9	as	as	IN
cord-257197-i9bucuma	170	10	the	the	DT
cord-257197-i9bucuma	170	11	initial	initial	JJ
cord-257197-i9bucuma	170	12	administration	administration	NN
cord-257197-i9bucuma	170	13	of	of	IN
cord-257197-i9bucuma	170	14	NPs	NPs	NNPS
cord-257197-i9bucuma	170	15	can	can	MD
cord-257197-i9bucuma	170	16	affect	affect	VB
cord-257197-i9bucuma	170	17	the	the	DT
cord-257197-i9bucuma	170	18	outcome	outcome	NN
cord-257197-i9bucuma	170	19	of	of	IN
cord-257197-i9bucuma	170	20	the	the	DT
cord-257197-i9bucuma	170	21	study	study	NN
cord-257197-i9bucuma	170	22	.	.	.
cord-257197-i9bucuma	171	1	Thus	thus	RB
cord-257197-i9bucuma	171	2	,	,	,
cord-257197-i9bucuma	171	3	to	to	TO
cord-257197-i9bucuma	171	4	be	be	VB
cord-257197-i9bucuma	171	5	able	able	JJ
cord-257197-i9bucuma	171	6	to	to	TO
cord-257197-i9bucuma	171	7	compare	compare	VB
cord-257197-i9bucuma	171	8	studies	study	NNS
cord-257197-i9bucuma	171	9	between	between	IN
cord-257197-i9bucuma	171	10	research	research	NN
cord-257197-i9bucuma	171	11	groups	group	NNS
cord-257197-i9bucuma	171	12	,	,	,
cord-257197-i9bucuma	171	13	we	-PRON-	PRP
cord-257197-i9bucuma	171	14	should	should	MD
cord-257197-i9bucuma	171	15	consider	consider	VB
cord-257197-i9bucuma	171	16	every	every	DT
cord-257197-i9bucuma	171	17	minor	minor	JJ
cord-257197-i9bucuma	171	18	detail	detail	NN
cord-257197-i9bucuma	171	19	and	and	CC
cord-257197-i9bucuma	171	20	develop	develop	VB
cord-257197-i9bucuma	171	21	a	a	DT
cord-257197-i9bucuma	171	22	robust	robust	JJ
cord-257197-i9bucuma	171	23	analytical	analytical	JJ
cord-257197-i9bucuma	171	24	method	method	NN
cord-257197-i9bucuma	171	25	.	.	.
cord-257197-i9bucuma	172	1	Due	due	IN
cord-257197-i9bucuma	172	2	to	to	IN
cord-257197-i9bucuma	172	3	a	a	DT
cord-257197-i9bucuma	172	4	lack	lack	NN
cord-257197-i9bucuma	172	5	of	of	IN
cord-257197-i9bucuma	172	6	standardized	standardized	JJ
cord-257197-i9bucuma	172	7	/	/	SYM
cord-257197-i9bucuma	172	8	universal	universal	JJ
cord-257197-i9bucuma	172	9	methods	method	NNS
cord-257197-i9bucuma	172	10	of	of	IN
cord-257197-i9bucuma	172	11	testing	testing	NN
cord-257197-i9bucuma	172	12	NPs	NPs	NNPS
cord-257197-i9bucuma	172	13	,	,	,
cord-257197-i9bucuma	172	14	it	-PRON-	PRP
cord-257197-i9bucuma	172	15	is	be	VBZ
cord-257197-i9bucuma	172	16	difficult	difficult	JJ
cord-257197-i9bucuma	172	17	to	to	TO
cord-257197-i9bucuma	172	18	compare	compare	VB
cord-257197-i9bucuma	172	19	and	and	CC
cord-257197-i9bucuma	172	20	obtain	obtain	VB
cord-257197-i9bucuma	172	21	a	a	DT
cord-257197-i9bucuma	172	22	better	well	JJR
cord-257197-i9bucuma	172	23	understanding	understanding	NN
cord-257197-i9bucuma	172	24	of	of	IN
cord-257197-i9bucuma	172	25	NPs	NPs	NNP
cord-257197-i9bucuma	172	26	bio	bio	NNP
cord-257197-i9bucuma	172	27	-	-	HYPH
cord-257197-i9bucuma	172	28	interactions	interaction	NNS
cord-257197-i9bucuma	172	29	.	.	.
cord-257197-i9bucuma	173	1	The	the	DT
cord-257197-i9bucuma	173	2	Hence	Hence	NNP
cord-257197-i9bucuma	173	3	,	,	,
cord-257197-i9bucuma	173	4	more	more	JJR
cord-257197-i9bucuma	173	5	studies	study	NNS
cord-257197-i9bucuma	173	6	are	be	VBP
cord-257197-i9bucuma	173	7	needed	need	VBN
cord-257197-i9bucuma	173	8	to	to	TO
cord-257197-i9bucuma	173	9	assess	assess	VB
cord-257197-i9bucuma	173	10	the	the	DT
cord-257197-i9bucuma	173	11	effect	effect	NN
cord-257197-i9bucuma	173	12	of	of	IN
cord-257197-i9bucuma	173	13	repeated	repeat	VBN
cord-257197-i9bucuma	173	14	exposure	exposure	NN
cord-257197-i9bucuma	173	15	to	to	IN
cord-257197-i9bucuma	173	16	NPs	NPs	NNP
cord-257197-i9bucuma	173	17	at	at	IN
cord-257197-i9bucuma	173	18	prescribed	prescribed	JJ
cord-257197-i9bucuma	173	19	intervals	interval	NNS
cord-257197-i9bucuma	173	20	.	.	.
cord-257197-i9bucuma	174	1	91	91	CD
cord-257197-i9bucuma	175	1	Gokduman	Gokduman	NNP
cord-257197-i9bucuma	175	2	et	et	FW
cord-257197-i9bucuma	175	3	al	al	NNP
cord-257197-i9bucuma	175	4	.	.	.
cord-257197-i9bucuma	176	1	91	91	CD
cord-257197-i9bucuma	177	1	Cell	cell	NN
cord-257197-i9bucuma	177	2	viability	viability	NN
cord-257197-i9bucuma	177	3	tests	test	NNS
cord-257197-i9bucuma	177	4	are	be	VBP
cord-257197-i9bucuma	177	5	widely	widely	RB
cord-257197-i9bucuma	177	6	used	use	VBN
cord-257197-i9bucuma	177	7	to	to	TO
cord-257197-i9bucuma	177	8	assess	assess	VB
cord-257197-i9bucuma	177	9	the	the	DT
cord-257197-i9bucuma	177	10	toxicity	toxicity	NN
cord-257197-i9bucuma	177	11	of	of	IN
cord-257197-i9bucuma	177	12	NPs	NPs	NNPS
cord-257197-i9bucuma	177	13	.	.	.
cord-257197-i9bucuma	178	1	This	this	DT
cord-257197-i9bucuma	178	2	typically	typically	RB
cord-257197-i9bucuma	178	3	involves	involve	VBZ
cord-257197-i9bucuma	178	4	a	a	DT
cord-257197-i9bucuma	178	5	single	single	JJ
cord-257197-i9bucuma	178	6	dose	dose	NN
cord-257197-i9bucuma	178	7	of	of	IN
cord-257197-i9bucuma	178	8	NPs	NPs	NNPS
cord-257197-i9bucuma	178	9	followed	follow	VBN
cord-257197-i9bucuma	178	10	by	by	IN
cord-257197-i9bucuma	178	11	short	short	JJ
cord-257197-i9bucuma	178	12	-	-	HYPH
cord-257197-i9bucuma	178	13	term	term	NN
cord-257197-i9bucuma	178	14	evaluations	evaluation	NNS
cord-257197-i9bucuma	178	15	of	of	IN
cord-257197-i9bucuma	178	16	viability	viability	NN
cord-257197-i9bucuma	178	17	.	.	.
cord-257197-i9bucuma	179	1	Whereas	whereas	IN
cord-257197-i9bucuma	179	2	,	,	,
cord-257197-i9bucuma	179	3	in	in	IN
cord-257197-i9bucuma	179	4	vivo	vivo	NNP
cord-257197-i9bucuma	179	5	studies	study	NNS
cord-257197-i9bucuma	179	6	focus	focus	VBP
cord-257197-i9bucuma	179	7	on	on	IN
cord-257197-i9bucuma	179	8	studying	study	VBG
cord-257197-i9bucuma	179	9	the	the	DT
cord-257197-i9bucuma	179	10	systemic	systemic	JJ
cord-257197-i9bucuma	179	11	effects	effect	NNS
cord-257197-i9bucuma	179	12	and	and	CC
cord-257197-i9bucuma	179	13	accumulation	accumulation	NN
cord-257197-i9bucuma	179	14	of	of	IN
cord-257197-i9bucuma	179	15	NPs	NPs	NNPS
cord-257197-i9bucuma	179	16	.	.	.
cord-257197-i9bucuma	180	1	Therefore	therefore	RB
cord-257197-i9bucuma	180	2	,	,	,
cord-257197-i9bucuma	180	3	there	there	EX
cord-257197-i9bucuma	180	4	is	be	VBZ
cord-257197-i9bucuma	180	5	an	an	DT
cord-257197-i9bucuma	180	6	apparent	apparent	JJ
cord-257197-i9bucuma	180	7	disconnect	disconnect	NN
cord-257197-i9bucuma	180	8	between	between	IN
cord-257197-i9bucuma	180	9	most	most	JJS
cord-257197-i9bucuma	180	10	in	in	IN
cord-257197-i9bucuma	180	11	vitro	vitro	FW
cord-257197-i9bucuma	180	12	and	and	CC
cord-257197-i9bucuma	180	13	in	in	IN
cord-257197-i9bucuma	180	14	vivo	vivo	NNP
cord-257197-i9bucuma	180	15	studies	study	NNS
cord-257197-i9bucuma	180	16	.	.	.
cord-257197-i9bucuma	181	1	120	120	CD
cord-257197-i9bucuma	181	2	Reactive	reactive	JJ
cord-257197-i9bucuma	181	3	oxygen	oxygen	NN
cord-257197-i9bucuma	181	4	species	specie	NNS
cord-257197-i9bucuma	181	5	produced	produce	VBN
cord-257197-i9bucuma	181	6	by	by	IN
cord-257197-i9bucuma	181	7	cells	cell	NNS
cord-257197-i9bucuma	181	8	in	in	IN
cord-257197-i9bucuma	181	9	response	response	NN
cord-257197-i9bucuma	181	10	to	to	IN
cord-257197-i9bucuma	181	11	NPs	NPs	NNP
cord-257197-i9bucuma	181	12	is	be	VBZ
cord-257197-i9bucuma	181	13	a	a	DT
cord-257197-i9bucuma	181	14	potent	potent	JJ
cord-257197-i9bucuma	181	15	early	early	JJ
cord-257197-i9bucuma	181	16	marker	marker	NN
cord-257197-i9bucuma	181	17	for	for	IN
cord-257197-i9bucuma	181	18	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	181	19	toxicity	toxicity	NN
cord-257197-i9bucuma	181	20	.	.	.
cord-257197-i9bucuma	182	1	94	94	CD
cord-257197-i9bucuma	182	2	119	119	CD
cord-257197-i9bucuma	182	3	Oxidative	oxidative	JJ
cord-257197-i9bucuma	182	4	stress	stress	NN
cord-257197-i9bucuma	182	5	exerted	exert	VBN
cord-257197-i9bucuma	182	6	by	by	IN
cord-257197-i9bucuma	182	7	NPs	NPs	NNPS
cord-257197-i9bucuma	182	8	may	may	MD
cord-257197-i9bucuma	182	9	be	be	VB
cord-257197-i9bucuma	182	10	inevitable	inevitable	JJ
cord-257197-i9bucuma	182	11	in	in	IN
cord-257197-i9bucuma	182	12	some	some	DT
cord-257197-i9bucuma	182	13	cases	case	NNS
cord-257197-i9bucuma	182	14	and	and	CC
cord-257197-i9bucuma	182	15	can	can	MD
cord-257197-i9bucuma	182	16	be	be	VB
cord-257197-i9bucuma	182	17	ameliorated	ameliorate	VBN
cord-257197-i9bucuma	182	18	by	by	IN
cord-257197-i9bucuma	182	19	the	the	DT
cord-257197-i9bucuma	182	20	naturally	naturally	RB
cord-257197-i9bucuma	182	21	occurring	occur	VBG
cord-257197-i9bucuma	182	22	antioxidants	antioxidant	NNS
cord-257197-i9bucuma	182	23	94	94	CD
cord-257197-i9bucuma	182	24	or	or	CC
cord-257197-i9bucuma	182	25	by	by	IN
cord-257197-i9bucuma	182	26	supplementation	supplementation	NN
cord-257197-i9bucuma	182	27	with	with	IN
cord-257197-i9bucuma	182	28	antioxidants	antioxidant	NNS
cord-257197-i9bucuma	182	29	such	such	JJ
cord-257197-i9bucuma	182	30	as	as	IN
cord-257197-i9bucuma	182	31	thymoquinone	thymoquinone	NN
cord-257197-i9bucuma	182	32	to	to	TO
cord-257197-i9bucuma	182	33	reduce	reduce	VB
cord-257197-i9bucuma	182	34	these	these	DT
cord-257197-i9bucuma	182	35	effects	effect	NNS
cord-257197-i9bucuma	182	36	.	.	.
cord-257197-i9bucuma	183	1	121	121	CD
cord-257197-i9bucuma	183	2	Feng	Feng	NNP
cord-257197-i9bucuma	183	3	et	et	FW
cord-257197-i9bucuma	183	4	al	al	NNP
cord-257197-i9bucuma	183	5	.	.	.
cord-257197-i9bucuma	184	1	99	99	CD
cord-257197-i9bucuma	184	2	observed	observe	VBD
cord-257197-i9bucuma	184	3	that	that	IN
cord-257197-i9bucuma	184	4	cationic	cationic	JJ
cord-257197-i9bucuma	184	5	PEI	PEI	NNP
cord-257197-i9bucuma	184	6	coated	coat	VBD
cord-257197-i9bucuma	184	7	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	184	8	were	be	VBD
cord-257197-i9bucuma	184	9	endocytosed	endocytose	VBN
cord-257197-i9bucuma	184	10	in	in	IN
cord-257197-i9bucuma	184	11	high	high	JJ
cord-257197-i9bucuma	184	12	numbers	number	NNS
cord-257197-i9bucuma	184	13	compared	compare	VBN
cord-257197-i9bucuma	184	14	to	to	IN
cord-257197-i9bucuma	184	15	PEG	PEG	NNP
cord-257197-i9bucuma	184	16	-	-	HYPH
cord-257197-i9bucuma	184	17	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	184	18	and	and	CC
cord-257197-i9bucuma	184	19	were	be	VBD
cord-257197-i9bucuma	184	20	more	more	RBR
cord-257197-i9bucuma	184	21	toxic	toxic	JJ
cord-257197-i9bucuma	184	22	to	to	IN
cord-257197-i9bucuma	184	23	cells	cell	NNS
cord-257197-i9bucuma	184	24	as	as	IN
cord-257197-i9bucuma	184	25	they	-PRON-	PRP
cord-257197-i9bucuma	184	26	dramatically	dramatically	RB
cord-257197-i9bucuma	184	27	reduced	reduce	VBD
cord-257197-i9bucuma	184	28	cell	cell	NN
cord-257197-i9bucuma	184	29	viability	viability	NN
cord-257197-i9bucuma	184	30	in	in	IN
cord-257197-i9bucuma	184	31	a	a	DT
cord-257197-i9bucuma	184	32	concentration	concentration	NN
cord-257197-i9bucuma	184	33	dependent	dependent	JJ
cord-257197-i9bucuma	184	34	manner	manner	NN
cord-257197-i9bucuma	184	35	.	.	.
cord-257197-i9bucuma	185	1	Increased	increase	VBN
cord-257197-i9bucuma	185	2	ROS	ROS	NNP
cord-257197-i9bucuma	185	3	generation	generation	NN
cord-257197-i9bucuma	185	4	that	that	WDT
cord-257197-i9bucuma	185	5	disrupted	disrupt	VBD
cord-257197-i9bucuma	185	6	the	the	DT
cord-257197-i9bucuma	185	7	cell	cell	NN
cord-257197-i9bucuma	185	8	cycle	cycle	NN
cord-257197-i9bucuma	185	9	by	by	IN
cord-257197-i9bucuma	185	10	arresting	arrest	VBG
cord-257197-i9bucuma	185	11	cells	cell	NNS
cord-257197-i9bucuma	185	12	in	in	IN
cord-257197-i9bucuma	185	13	G2-phase	g2-phase	JJ
cord-257197-i9bucuma	185	14	cell	cell	NN
cord-257197-i9bucuma	185	15	cycle	cycle	NN
cord-257197-i9bucuma	185	16	,	,	,
cord-257197-i9bucuma	185	17	led	lead	VBD
cord-257197-i9bucuma	185	18	to	to	IN
cord-257197-i9bucuma	185	19	apoptosis	apoptosis	NN
cord-257197-i9bucuma	185	20	.	.	.
cord-257197-i9bucuma	186	1	Genotoxicity	Genotoxicity	NNP
cord-257197-i9bucuma	186	2	induced	induce	VBN
cord-257197-i9bucuma	186	3	by	by	IN
cord-257197-i9bucuma	186	4	the	the	DT
cord-257197-i9bucuma	186	5	PEI	PEI	NNP
cord-257197-i9bucuma	186	6	-	-	HYPH
cord-257197-i9bucuma	186	7	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	186	8	was	be	VBD
cord-257197-i9bucuma	186	9	observed	observe	VBN
cord-257197-i9bucuma	186	10	to	to	TO
cord-257197-i9bucuma	186	11	be	be	VB
cord-257197-i9bucuma	186	12	an	an	DT
cord-257197-i9bucuma	186	13	indirect	indirect	JJ
cord-257197-i9bucuma	186	14	effect	effect	NN
cord-257197-i9bucuma	186	15	and	and	CC
cord-257197-i9bucuma	186	16	not	not	RB
cord-257197-i9bucuma	186	17	due	due	JJ
cord-257197-i9bucuma	186	18	to	to	IN
cord-257197-i9bucuma	186	19	direct	direct	JJ
cord-257197-i9bucuma	186	20	interaction	interaction	NN
cord-257197-i9bucuma	186	21	with	with	IN
cord-257197-i9bucuma	186	22	the	the	DT
cord-257197-i9bucuma	186	23	DNA	dna	NN
cord-257197-i9bucuma	186	24	.	.	.
cord-257197-i9bucuma	187	1	99	99	CD
cord-257197-i9bucuma	188	1	In	in	IN
cord-257197-i9bucuma	188	2	contrast	contrast	NN
cord-257197-i9bucuma	188	3	60	60	CD
cord-257197-i9bucuma	188	4	nm	nm	NN
cord-257197-i9bucuma	188	5	'	'	``
cord-257197-i9bucuma	188	6	naked	naked	JJ
cord-257197-i9bucuma	188	7	'	'	''
cord-257197-i9bucuma	188	8	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	188	9	intercalated	intercalate	VBN
cord-257197-i9bucuma	188	10	with	with	IN
cord-257197-i9bucuma	188	11	DNA	dna	NN
cord-257197-i9bucuma	188	12	base	base	NN
cord-257197-i9bucuma	188	13	pairs	pair	NNS
cord-257197-i9bucuma	188	14	in	in	IN
cord-257197-i9bucuma	188	15	primary	primary	JJ
cord-257197-i9bucuma	188	16	lymphocytes	lymphocyte	NNS
cord-257197-i9bucuma	188	17	and	and	CC
cord-257197-i9bucuma	188	18	generated	generate	VBD
cord-257197-i9bucuma	188	19	high	high	JJ
cord-257197-i9bucuma	188	20	levels	level	NNS
cord-257197-i9bucuma	188	21	of	of	IN
cord-257197-i9bucuma	188	22	ROS	ROS	NNP
cord-257197-i9bucuma	188	23	that	that	WDT
cord-257197-i9bucuma	188	24	reduced	reduce	VBD
cord-257197-i9bucuma	188	25	the	the	DT
cord-257197-i9bucuma	188	26	cell	cell	NN
cord-257197-i9bucuma	188	27	viability	viability	NN
cord-257197-i9bucuma	188	28	.	.	.
cord-257197-i9bucuma	189	1	121	121	CD
cord-257197-i9bucuma	189	2	 	 	_SP
cord-257197-i9bucuma	189	3	Cells	cell	NNS
cord-257197-i9bucuma	189	4	may	may	MD
cord-257197-i9bucuma	189	5	use	use	VB
cord-257197-i9bucuma	189	6	an	an	DT
cord-257197-i9bucuma	189	7	active	active	JJ
cord-257197-i9bucuma	189	8	,	,	,
cord-257197-i9bucuma	189	9	energy	energy	NN
cord-257197-i9bucuma	189	10	dependent	dependent	JJ
cord-257197-i9bucuma	189	11	endocytic	endocytic	JJ
cord-257197-i9bucuma	189	12	pathway	pathway	NN
cord-257197-i9bucuma	189	13	or	or	CC
cord-257197-i9bucuma	189	14	energy	energy	NN
cord-257197-i9bucuma	189	15	independent	independent	NNP
cord-257197-i9bucuma	189	16	passive	passive	JJ
cord-257197-i9bucuma	189	17	diffusion	diffusion	NN
cord-257197-i9bucuma	189	18	to	to	TO
cord-257197-i9bucuma	189	19	internalize	internalize	VB
cord-257197-i9bucuma	189	20	NPs	NPs	NNP
cord-257197-i9bucuma	189	21	.	.	.
cord-257197-i9bucuma	190	1	Table	table	NN
cord-257197-i9bucuma	190	2	4	4	CD
cord-257197-i9bucuma	190	3	summarizes	summarize	VBZ
cord-257197-i9bucuma	190	4	the	the	DT
cord-257197-i9bucuma	190	5	uptake	uptake	NN
cord-257197-i9bucuma	190	6	pathways	pathway	NNS
cord-257197-i9bucuma	190	7	used	use	VBN
cord-257197-i9bucuma	190	8	by	by	IN
cord-257197-i9bucuma	190	9	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	190	10	with	with	IN
cord-257197-i9bucuma	190	11	different	different	JJ
cord-257197-i9bucuma	190	12	surface	surface	NN
cord-257197-i9bucuma	190	13	chemistries	chemistry	NNS
cord-257197-i9bucuma	190	14	in	in	IN
cord-257197-i9bucuma	190	15	various	various	JJ
cord-257197-i9bucuma	190	16	cell	cell	NN
cord-257197-i9bucuma	190	17	types	type	NNS
cord-257197-i9bucuma	190	18	.	.	.
cord-257197-i9bucuma	191	1	Endocytosis	endocytosis	NN
cord-257197-i9bucuma	191	2	is	be	VBZ
cord-257197-i9bucuma	191	3	broadly	broadly	RB
cord-257197-i9bucuma	191	4	classified	classify	VBN
cord-257197-i9bucuma	191	5	as	as	IN
cord-257197-i9bucuma	191	6	-Clathrin	-clathrin	RB
cord-257197-i9bucuma	191	7	mediated	mediate	VBN
cord-257197-i9bucuma	191	8	endocytosis	endocytosis	NN
cord-257197-i9bucuma	191	9	(	(	-LRB-
cord-257197-i9bucuma	191	10	CME	CME	NNP
cord-257197-i9bucuma	191	11	)	)	-RRB-
cord-257197-i9bucuma	191	12	,	,	,
cord-257197-i9bucuma	191	13	caveolae	caveolae	NNP
cord-257197-i9bucuma	191	14	mediated	mediate	VBD
cord-257197-i9bucuma	191	15	endocytosis	endocytosis	NN
cord-257197-i9bucuma	191	16	(	(	-LRB-
cord-257197-i9bucuma	191	17	CvME	CvME	NNP
cord-257197-i9bucuma	191	18	)	)	-RRB-
cord-257197-i9bucuma	191	19	,	,	,
cord-257197-i9bucuma	191	20	macropinocytosis	macropinocytosis	NNP
cord-257197-i9bucuma	191	21	and	and	CC
cord-257197-i9bucuma	191	22	clathrin	clathrin	NNP
cord-257197-i9bucuma	191	23	and	and	CC
cord-257197-i9bucuma	191	24	caveolae	caveolae	NNP
cord-257197-i9bucuma	191	25	independent	independent	JJ
cord-257197-i9bucuma	191	26	endocytosis	endocytosis	NNP
cord-257197-i9bucuma	191	27	.	.	.
cord-257197-i9bucuma	192	1	Phagocytosis	Phagocytosis	NNP
cord-257197-i9bucuma	192	2	is	be	VBZ
cord-257197-i9bucuma	192	3	a	a	DT
cord-257197-i9bucuma	192	4	type	type	NN
cord-257197-i9bucuma	192	5	of	of	IN
cord-257197-i9bucuma	192	6	endocytic	endocytic	JJ
cord-257197-i9bucuma	192	7	pathway	pathway	NN
cord-257197-i9bucuma	192	8	which	which	WDT
cord-257197-i9bucuma	192	9	is	be	VBZ
cord-257197-i9bucuma	192	10	only	only	RB
cord-257197-i9bucuma	192	11	employed	employ	VBN
cord-257197-i9bucuma	192	12	by	by	IN
cord-257197-i9bucuma	192	13	immune	immune	JJ
cord-257197-i9bucuma	192	14	cells	cell	NNS
cord-257197-i9bucuma	192	15	such	such	JJ
cord-257197-i9bucuma	192	16	as	as	IN
cord-257197-i9bucuma	192	17	macrophages	macrophage	NNS
cord-257197-i9bucuma	192	18	,	,	,
cord-257197-i9bucuma	192	19	neutrophils	neutrophil	NNS
cord-257197-i9bucuma	192	20	and	and	CC
cord-257197-i9bucuma	192	21	dendritic	dendritic	JJ
cord-257197-i9bucuma	192	22	cells	cell	NNS
cord-257197-i9bucuma	192	23	.	.	.
cord-257197-i9bucuma	193	1	127	127	CD
cord-257197-i9bucuma	193	2	Cargo	Cargo	NNP
cord-257197-i9bucuma	193	3	is	be	VBZ
cord-257197-i9bucuma	193	4	transported	transport	VBN
cord-257197-i9bucuma	193	5	intracellularly	intracellularly	RB
cord-257197-i9bucuma	193	6	in	in	IN
cord-257197-i9bucuma	193	7	endocytic	endocytic	JJ
cord-257197-i9bucuma	193	8	vesicles	vesicle	NNS
cord-257197-i9bucuma	193	9	formed	form	VBN
cord-257197-i9bucuma	193	10	by	by	IN
cord-257197-i9bucuma	193	11	cell	cell	NN
cord-257197-i9bucuma	193	12	membrane	membrane	NN
cord-257197-i9bucuma	193	13	invaginations	invagination	NNS
cord-257197-i9bucuma	193	14	.	.	.
cord-257197-i9bucuma	194	1	Endocytic	endocytic	JJ
cord-257197-i9bucuma	194	2	vesicles	vesicle	NNS
cord-257197-i9bucuma	194	3	can	can	MD
cord-257197-i9bucuma	194	4	be	be	VB
cord-257197-i9bucuma	194	5	classified	classify	VBN
cord-257197-i9bucuma	194	6	based	base	VBN
cord-257197-i9bucuma	194	7	on	on	IN
cord-257197-i9bucuma	194	8	the	the	DT
cord-257197-i9bucuma	194	9	protein	protein	NN
cord-257197-i9bucuma	194	10	markers	marker	NNS
cord-257197-i9bucuma	194	11	on	on	IN
cord-257197-i9bucuma	194	12	the	the	DT
cord-257197-i9bucuma	194	13	vesicle	vesicle	NN
cord-257197-i9bucuma	194	14	membrane	membrane	NN
cord-257197-i9bucuma	194	15	associated	associate	VBN
cord-257197-i9bucuma	194	16	with	with	IN
cord-257197-i9bucuma	194	17	the	the	DT
cord-257197-i9bucuma	194	18	endocytic	endocytic	JJ
cord-257197-i9bucuma	194	19	pathway	pathway	NN
cord-257197-i9bucuma	194	20	,	,	,
cord-257197-i9bucuma	194	21	further	further	RB
cord-257197-i9bucuma	194	22	influencing	influence	VBG
cord-257197-i9bucuma	194	23	the	the	DT
cord-257197-i9bucuma	194	24	cargo	cargo	NN
cord-257197-i9bucuma	194	25	's	's	POS
cord-257197-i9bucuma	194	26	intracellular	intracellular	JJ
cord-257197-i9bucuma	194	27	sorting	sorting	NN
cord-257197-i9bucuma	194	28	.	.	.
cord-257197-i9bucuma	195	1	(	(	-LRB-
cord-257197-i9bucuma	195	2	Fig	Fig	NNP
cord-257197-i9bucuma	195	3	.	.	NNP
cord-257197-i9bucuma	195	4	4	4	LS
cord-257197-i9bucuma	195	5	)	)	-RRB-
cord-257197-i9bucuma	195	6	CME	CME	NNP
cord-257197-i9bucuma	195	7	and	and	CC
cord-257197-i9bucuma	195	8	macropinocytosis	macropinocytosis	NNP
cord-257197-i9bucuma	195	9	promote	promote	VBP
cord-257197-i9bucuma	195	10	the	the	DT
cord-257197-i9bucuma	195	11	fusion	fusion	NN
cord-257197-i9bucuma	195	12	of	of	IN
cord-257197-i9bucuma	195	13	endocytic	endocytic	JJ
cord-257197-i9bucuma	195	14	vesicles	vesicle	NNS
cord-257197-i9bucuma	195	15	with	with	IN
cord-257197-i9bucuma	195	16	the	the	DT
cord-257197-i9bucuma	195	17	highly	highly	RB
cord-257197-i9bucuma	195	18	acidic	acidic	JJ
cord-257197-i9bucuma	195	19	lysosomes	lysosome	NNS
cord-257197-i9bucuma	195	20	(	(	-LRB-
cord-257197-i9bucuma	195	21	~	~	NFP
cord-257197-i9bucuma	195	22	pH	ph	NN
cord-257197-i9bucuma	195	23	5	5	CD
cord-257197-i9bucuma	195	24	)	)	-RRB-
cord-257197-i9bucuma	195	25	that	that	WDT
cord-257197-i9bucuma	195	26	can	can	MD
cord-257197-i9bucuma	195	27	cause	cause	VB
cord-257197-i9bucuma	195	28	degradation	degradation	NN
cord-257197-i9bucuma	195	29	of	of	IN
cord-257197-i9bucuma	195	30	the	the	DT
cord-257197-i9bucuma	195	31	functionalizing	functionalize	VBG
cord-257197-i9bucuma	195	32	ligands	ligand	NNS
cord-257197-i9bucuma	195	33	and	and	CC
cord-257197-i9bucuma	195	34	NPs	NPs	NNPS
cord-257197-i9bucuma	195	35	themselves	-PRON-	PRP
cord-257197-i9bucuma	195	36	.	.	.
cord-257197-i9bucuma	196	1	While	while	IN
cord-257197-i9bucuma	196	2	the	the	DT
cord-257197-i9bucuma	196	3	cargo	cargo	NN
cord-257197-i9bucuma	196	4	transported	transport	VBN
cord-257197-i9bucuma	196	5	in	in	IN
cord-257197-i9bucuma	196	6	the	the	DT
cord-257197-i9bucuma	196	7	caveosomes	caveosome	NNS
cord-257197-i9bucuma	196	8	,	,	,
cord-257197-i9bucuma	196	9	enter	enter	VB
cord-257197-i9bucuma	196	10	the	the	DT
cord-257197-i9bucuma	196	11	Golgi	Golgi	NNP
cord-257197-i9bucuma	196	12	and	and	CC
cord-257197-i9bucuma	196	13	endoplasmic	endoplasmic	NN
cord-257197-i9bucuma	196	14	reticulum	reticulum	NN
cord-257197-i9bucuma	196	15	,	,	,
cord-257197-i9bucuma	196	16	bypassing	bypass	VBG
cord-257197-i9bucuma	196	17	the	the	DT
cord-257197-i9bucuma	196	18	lysosomes	lysosome	NNS
cord-257197-i9bucuma	196	19	.	.	.
cord-257197-i9bucuma	197	1	CvME	CvME	NNP
cord-257197-i9bucuma	197	2	also	also	RB
cord-257197-i9bucuma	197	3	favor	favor	VBP
cord-257197-i9bucuma	197	4	transcytosis	transcytosis	NN
cord-257197-i9bucuma	197	5	like	like	IN
cord-257197-i9bucuma	197	6	in	in	IN
cord-257197-i9bucuma	197	7	the	the	DT
cord-257197-i9bucuma	197	8	case	case	NN
cord-257197-i9bucuma	197	9	of	of	IN
cord-257197-i9bucuma	197	10	Nab	Nab	NNP
cord-257197-i9bucuma	197	11	-	-	HYPH
cord-257197-i9bucuma	197	12	paclitaxel	paclitaxel	RB
cord-257197-i9bucuma	197	13	.	.	.
cord-257197-i9bucuma	198	1	[	[	-LRB-
cord-257197-i9bucuma	198	2	127	127	CD
cord-257197-i9bucuma	198	3	]	]	-RRB-
cord-257197-i9bucuma	198	4	[	[	-LRB-
cord-257197-i9bucuma	198	5	128	128	CD
cord-257197-i9bucuma	198	6	]	]	-RRB-
cord-257197-i9bucuma	198	7	[	[	-LRB-
cord-257197-i9bucuma	198	8	129	129	CD
cord-257197-i9bucuma	198	9	]	]	-RRB-
cord-257197-i9bucuma	199	1	[	[	-LRB-
cord-257197-i9bucuma	199	2	130	130	CD
cord-257197-i9bucuma	199	3	]	]	-RRB-
cord-257197-i9bucuma	200	1	Some	some	DT
cord-257197-i9bucuma	200	2	oncology	oncology	NN
cord-257197-i9bucuma	200	3	and	and	CC
cord-257197-i9bucuma	200	4	viral	viral	JJ
cord-257197-i9bucuma	200	5	medications	medication	NNS
cord-257197-i9bucuma	200	6	such	such	JJ
cord-257197-i9bucuma	200	7	as	as	IN
cord-257197-i9bucuma	200	8	trastuzumab	trastuzumab	NNP
cord-257197-i9bucuma	200	9	emtansine	emtansine	NNP
cord-257197-i9bucuma	200	10	(	(	-LRB-
cord-257197-i9bucuma	200	11	T	T	NNP
cord-257197-i9bucuma	200	12	-	-	HYPH
cord-257197-i9bucuma	200	13	DMI	DMI	NNP
cord-257197-i9bucuma	200	14	)	)	-RRB-
cord-257197-i9bucuma	201	1	131	131	CD
cord-257197-i9bucuma	201	2	and	and	CC
cord-257197-i9bucuma	201	3	chloroquine	chloroquine	NN
cord-257197-i9bucuma	201	4	132	132	CD
cord-257197-i9bucuma	201	5	,	,	,
cord-257197-i9bucuma	201	6	respectively	respectively	RB
cord-257197-i9bucuma	201	7	,	,	,
cord-257197-i9bucuma	201	8	target	target	VB
cord-257197-i9bucuma	201	9	the	the	DT
cord-257197-i9bucuma	201	10	endocytosis	endocytosis	NN
cord-257197-i9bucuma	201	11	pathways	pathway	NNS
cord-257197-i9bucuma	201	12	.	.	.
cord-257197-i9bucuma	202	1	Hence	hence	RB
cord-257197-i9bucuma	202	2	,	,	,
cord-257197-i9bucuma	202	3	studying	study	VBG
cord-257197-i9bucuma	202	4	the	the	DT
cord-257197-i9bucuma	202	5	mechanism	mechanism	NN
cord-257197-i9bucuma	202	6	of	of	IN
cord-257197-i9bucuma	202	7	uptake	uptake	NN
cord-257197-i9bucuma	202	8	is	be	VBZ
cord-257197-i9bucuma	202	9	important	important	JJ
cord-257197-i9bucuma	202	10	for	for	IN
cord-257197-i9bucuma	202	11	the	the	DT
cord-257197-i9bucuma	202	12	fundamental	fundamental	JJ
cord-257197-i9bucuma	202	13	understanding	understanding	NN
cord-257197-i9bucuma	202	14	of	of	IN
cord-257197-i9bucuma	202	15	nano	nano	NNP
cord-257197-i9bucuma	202	16	-	-	HYPH
cord-257197-i9bucuma	202	17	bio	bio	JJ
cord-257197-i9bucuma	202	18	interactions	interaction	NNS
cord-257197-i9bucuma	202	19	and	and	CC
cord-257197-i9bucuma	202	20	drug	drug	NN
cord-257197-i9bucuma	202	21	delivery	delivery	NN
cord-257197-i9bucuma	202	22	.	.	.
cord-257197-i9bucuma	203	1	Chemical	chemical	NN
cord-257197-i9bucuma	203	2	inhibitors	inhibitor	NNS
cord-257197-i9bucuma	203	3	of	of	IN
cord-257197-i9bucuma	203	4	endocytosis	endocytosis	NN
cord-257197-i9bucuma	203	5	are	be	VBP
cord-257197-i9bucuma	203	6	commonly	commonly	RB
cord-257197-i9bucuma	203	7	used	use	VBN
cord-257197-i9bucuma	203	8	to	to	TO
cord-257197-i9bucuma	203	9	study	study	VB
cord-257197-i9bucuma	203	10	the	the	DT
cord-257197-i9bucuma	203	11	endocytic	endocytic	JJ
cord-257197-i9bucuma	203	12	uptake	uptake	NN
cord-257197-i9bucuma	203	13	pathways	pathway	NNS
cord-257197-i9bucuma	203	14	.	.	.
cord-257197-i9bucuma	204	1	Some	some	DT
cord-257197-i9bucuma	204	2	inhibitors	inhibitor	NNS
cord-257197-i9bucuma	204	3	may	may	MD
cord-257197-i9bucuma	204	4	have	have	VB
cord-257197-i9bucuma	204	5	a	a	DT
cord-257197-i9bucuma	204	6	generalized	generalized	JJ
cord-257197-i9bucuma	204	7	inhibitory	inhibitory	JJ
cord-257197-i9bucuma	204	8	effect	effect	NN
cord-257197-i9bucuma	204	9	while	while	IN
cord-257197-i9bucuma	204	10	some	some	DT
cord-257197-i9bucuma	204	11	are	be	VBP
cord-257197-i9bucuma	204	12	relatively	relatively	RB
cord-257197-i9bucuma	204	13	J	J	NNP
cord-257197-i9bucuma	204	14	o	o	NN
cord-257197-i9bucuma	204	15	u	u	NN
cord-257197-i9bucuma	204	16	r	r	NN
cord-257197-i9bucuma	204	17	n	n	NN
cord-257197-i9bucuma	204	18	a	a	DT
cord-257197-i9bucuma	204	19	l	l	NN
cord-257197-i9bucuma	204	20	P	p	NN
cord-257197-i9bucuma	204	21	r	r	NN
cord-257197-i9bucuma	204	22	e	e	NN
cord-257197-i9bucuma	204	23	-p	-p	NN
cord-257197-i9bucuma	205	1	r	r	LS
cord-257197-i9bucuma	205	2	o	o	NN
cord-257197-i9bucuma	206	1	o	o	UH
cord-257197-i9bucuma	206	2	f	f	NNP
cord-257197-i9bucuma	206	3	more	more	RBR
cord-257197-i9bucuma	206	4	specific	specific	JJ
cord-257197-i9bucuma	206	5	.	.	.
cord-257197-i9bucuma	207	1	Methyl	methyl	NN
cord-257197-i9bucuma	207	2	-	-	HYPH
cord-257197-i9bucuma	207	3	β	β	NN
cord-257197-i9bucuma	207	4	-	-	HYPH
cord-257197-i9bucuma	207	5	cyclodextrin	cyclodextrin	NN
cord-257197-i9bucuma	208	1	although	although	IN
cord-257197-i9bucuma	208	2	commonly	commonly	RB
cord-257197-i9bucuma	208	3	used	use	VBN
cord-257197-i9bucuma	208	4	as	as	IN
cord-257197-i9bucuma	208	5	an	an	DT
cord-257197-i9bucuma	208	6	inhibitor	inhibitor	NN
cord-257197-i9bucuma	208	7	of	of	IN
cord-257197-i9bucuma	208	8	CvME	CvME	NNP
cord-257197-i9bucuma	208	9	,	,	,
cord-257197-i9bucuma	208	10	it	-PRON-	PRP
cord-257197-i9bucuma	208	11	can	can	MD
cord-257197-i9bucuma	208	12	also	also	RB
cord-257197-i9bucuma	208	13	inhibit	inhibit	VB
cord-257197-i9bucuma	208	14	cholesterol	cholesterol	NN
cord-257197-i9bucuma	208	15	dependent	dependent	JJ
cord-257197-i9bucuma	208	16	clathrin	clathrin	NN
cord-257197-i9bucuma	208	17	and	and	CC
cord-257197-i9bucuma	208	18	caveolin	caveolin	JJ
cord-257197-i9bucuma	208	19	independent	independent	JJ
cord-257197-i9bucuma	208	20	pathways	pathway	NNS
cord-257197-i9bucuma	208	21	.	.	.
cord-257197-i9bucuma	209	1	133	133	CD
cord-257197-i9bucuma	210	1	Similarly	similarly	RB
cord-257197-i9bucuma	210	2	,	,	,
cord-257197-i9bucuma	210	3	dynasore	dynasore	NNP
cord-257197-i9bucuma	210	4	may	may	MD
cord-257197-i9bucuma	210	5	inhibit	inhibit	VB
cord-257197-i9bucuma	210	6	dynamin	dynamin	NNP
cord-257197-i9bucuma	210	7	independent	independent	JJ
cord-257197-i9bucuma	210	8	endocytic	endocytic	JJ
cord-257197-i9bucuma	210	9	pathways	pathway	NNS
cord-257197-i9bucuma	210	10	as	as	RB
cord-257197-i9bucuma	210	11	well	well	RB
cord-257197-i9bucuma	210	12	.	.	.
cord-257197-i9bucuma	211	1	134	134	CD
cord-257197-i9bucuma	212	1	Therefore	therefore	RB
cord-257197-i9bucuma	212	2	,	,	,
cord-257197-i9bucuma	212	3	the	the	DT
cord-257197-i9bucuma	212	4	chemical	chemical	NN
cord-257197-i9bucuma	212	5	inhibitors	inhibitor	NNS
cord-257197-i9bucuma	212	6	should	should	MD
cord-257197-i9bucuma	212	7	be	be	VB
cord-257197-i9bucuma	212	8	selected	select	VBN
cord-257197-i9bucuma	212	9	wisely	wisely	RB
cord-257197-i9bucuma	212	10	and	and	CC
cord-257197-i9bucuma	212	11	the	the	DT
cord-257197-i9bucuma	212	12	results	result	NNS
cord-257197-i9bucuma	212	13	should	should	MD
cord-257197-i9bucuma	212	14	be	be	VB
cord-257197-i9bucuma	212	15	interpreted	interpret	VBN
cord-257197-i9bucuma	212	16	appropriately	appropriately	RB
cord-257197-i9bucuma	212	17	.	.	.
cord-257197-i9bucuma	213	1	siRNA	siRNA	NNP
cord-257197-i9bucuma	213	2	mediated	mediate	VBD
cord-257197-i9bucuma	213	3	knockdown	knockdown	NN
cord-257197-i9bucuma	213	4	of	of	IN
cord-257197-i9bucuma	213	5	proteins	protein	NNS
cord-257197-i9bucuma	213	6	,	,	,
cord-257197-i9bucuma	213	7	essential	essential	JJ
cord-257197-i9bucuma	213	8	to	to	IN
cord-257197-i9bucuma	213	9	specific	specific	JJ
cord-257197-i9bucuma	213	10	endocytic	endocytic	JJ
cord-257197-i9bucuma	213	11	routes	route	NNS
cord-257197-i9bucuma	213	12	on	on	IN
cord-257197-i9bucuma	213	13	the	the	DT
cord-257197-i9bucuma	213	14	other	other	JJ
cord-257197-i9bucuma	213	15	hand	hand	NN
cord-257197-i9bucuma	213	16	is	be	VBZ
cord-257197-i9bucuma	213	17	less	less	RBR
cord-257197-i9bucuma	213	18	ambiguous	ambiguous	JJ
cord-257197-i9bucuma	213	19	than	than	IN
cord-257197-i9bucuma	213	20	chemical	chemical	JJ
cord-257197-i9bucuma	213	21	inhibitors	inhibitor	NNS
cord-257197-i9bucuma	213	22	.	.	.
cord-257197-i9bucuma	214	1	135	135	CD
cord-257197-i9bucuma	215	1	In	in	IN
cord-257197-i9bucuma	215	2	some	some	DT
cord-257197-i9bucuma	215	3	cases	case	NNS
cord-257197-i9bucuma	215	4	other	other	JJ
cord-257197-i9bucuma	215	5	endocytic	endocytic	JJ
cord-257197-i9bucuma	215	6	pathways	pathway	NNS
cord-257197-i9bucuma	215	7	may	may	MD
cord-257197-i9bucuma	215	8	be	be	VB
cord-257197-i9bucuma	215	9	upregulated	upregulate	VBN
cord-257197-i9bucuma	215	10	to	to	TO
cord-257197-i9bucuma	215	11	compensate	compensate	VB
cord-257197-i9bucuma	215	12	for	for	IN
cord-257197-i9bucuma	215	13	inhibition	inhibition	NN
cord-257197-i9bucuma	215	14	of	of	IN
cord-257197-i9bucuma	215	15	one	one	CD
cord-257197-i9bucuma	215	16	pathway	pathway	NN
cord-257197-i9bucuma	215	17	.	.	.
cord-257197-i9bucuma	216	1	Although	although	IN
cord-257197-i9bucuma	216	2	the	the	DT
cord-257197-i9bucuma	216	3	net	net	JJ
cord-257197-i9bucuma	216	4	uptake	uptake	NN
cord-257197-i9bucuma	216	5	of	of	IN
cord-257197-i9bucuma	216	6	NPs	NPs	NNPS
cord-257197-i9bucuma	216	7	may	may	MD
cord-257197-i9bucuma	216	8	seemingly	seemingly	RB
cord-257197-i9bucuma	216	9	be	be	VB
cord-257197-i9bucuma	216	10	unaffected	unaffected	JJ
cord-257197-i9bucuma	216	11	,	,	,
cord-257197-i9bucuma	216	12	one	one	PRP
cord-257197-i9bucuma	216	13	should	should	MD
cord-257197-i9bucuma	216	14	not	not	RB
cord-257197-i9bucuma	216	15	discount	discount	VB
cord-257197-i9bucuma	216	16	changes	change	NNS
cord-257197-i9bucuma	216	17	in	in	IN
cord-257197-i9bucuma	216	18	the	the	DT
cord-257197-i9bucuma	216	19	uptake	uptake	NN
cord-257197-i9bucuma	216	20	mechanism	mechanism	NN
cord-257197-i9bucuma	216	21	.	.	.
cord-257197-i9bucuma	217	1	71	71	CD
cord-257197-i9bucuma	217	2	,	,	,
cord-257197-i9bucuma	217	3	135	135	CD
cord-257197-i9bucuma	217	4	,	,	,
cord-257197-i9bucuma	217	5	136	136	CD
cord-257197-i9bucuma	217	6	Endocytosis	Endocytosis	NNP
cord-257197-i9bucuma	217	7	of	of	IN
cord-257197-i9bucuma	217	8	NPs	NPs	NNPS
cord-257197-i9bucuma	217	9	is	be	VBZ
cord-257197-i9bucuma	217	10	time	time	NN
cord-257197-i9bucuma	217	11	dependent	dependent	JJ
cord-257197-i9bucuma	217	12	.	.	.
cord-257197-i9bucuma	218	1	137	137	CD
cord-257197-i9bucuma	219	1	He	-PRON-	PRP
cord-257197-i9bucuma	219	2	et	et	FW
cord-257197-i9bucuma	219	3	al	al	NNP
cord-257197-i9bucuma	219	4	.	.	.
cord-257197-i9bucuma	220	1	138	138	CD
cord-257197-i9bucuma	220	2	observed	observe	VBD
cord-257197-i9bucuma	220	3	that	that	IN
cord-257197-i9bucuma	220	4	although	although	IN
cord-257197-i9bucuma	220	5	the	the	DT
cord-257197-i9bucuma	220	6	uptake	uptake	NN
cord-257197-i9bucuma	220	7	of	of	IN
cord-257197-i9bucuma	220	8	cationic	cationic	JJ
cord-257197-i9bucuma	220	9	CALRRRRRRRR	CALRRRRRRRR	NNP
cord-257197-i9bucuma	220	10	(	(	-LRB-
cord-257197-i9bucuma	220	11	R8	R8	NNP
cord-257197-i9bucuma	220	12	)	)	-RRB-
cord-257197-i9bucuma	220	13	peptide	peptide	NN
cord-257197-i9bucuma	220	14	functionalized	functionalize	VBN
cord-257197-i9bucuma	220	15	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	220	16	was	be	VBD
cord-257197-i9bucuma	220	17	slower	slow	JJR
cord-257197-i9bucuma	220	18	in	in	IN
cord-257197-i9bucuma	220	19	comparison	comparison	NN
cord-257197-i9bucuma	220	20	to	to	IN
cord-257197-i9bucuma	220	21	the	the	DT
cord-257197-i9bucuma	220	22	hydrophobic	hydrophobic	JJ
cord-257197-i9bucuma	220	23	CALNNPFVYLI	calnnpfvyli	NN
cord-257197-i9bucuma	221	1	(	(	-LRB-
cord-257197-i9bucuma	221	2	PFV	PFV	NNP
cord-257197-i9bucuma	221	3	)	)	-RRB-
cord-257197-i9bucuma	221	4	peptide	peptide	NN
cord-257197-i9bucuma	221	5	coated	coat	VBD
cord-257197-i9bucuma	221	6	AuNPs	AuNPs	NNP
cord-257197-i9bucuma	221	7	,	,	,
cord-257197-i9bucuma	221	8	in	in	IN
cord-257197-i9bucuma	221	9	the	the	DT
cord-257197-i9bucuma	221	10	initial	initial	JJ
cord-257197-i9bucuma	221	11	one	one	CD
cord-257197-i9bucuma	221	12	hour	hour	NN
cord-257197-i9bucuma	221	13	,	,	,
cord-257197-i9bucuma	221	14	their	-PRON-	PRP$
cord-257197-i9bucuma	221	15	net	net	JJ
cord-257197-i9bucuma	221	16	uptake	uptake	NN
cord-257197-i9bucuma	221	17	was	be	VBD
cord-257197-i9bucuma	221	18	higher	high	JJR
cord-257197-i9bucuma	221	19	at	at	IN
cord-257197-i9bucuma	221	20	the	the	DT
cord-257197-i9bucuma	221	21	end	end	NN
cord-257197-i9bucuma	221	22	of	of	IN
cord-257197-i9bucuma	221	23	12	12	CD
cord-257197-i9bucuma	221	24	h	h	NN
cord-257197-i9bucuma	221	25	of	of	IN
cord-257197-i9bucuma	221	26	incubation	incubation	NN
cord-257197-i9bucuma	221	27	.	.	.
cord-257197-i9bucuma	222	1	IEC-18	iec-18	CD
cord-257197-i9bucuma	222	2	epithelial	epithelial	JJ
cord-257197-i9bucuma	222	3	cells	cell	NNS
cord-257197-i9bucuma	222	4	also	also	RB
cord-257197-i9bucuma	222	5	seemed	seem	VBD
cord-257197-i9bucuma	222	6	to	to	TO
cord-257197-i9bucuma	222	7	use	use	VB
cord-257197-i9bucuma	222	8	different	different	JJ
cord-257197-i9bucuma	222	9	endocytosis	endocytosis	NN
cord-257197-i9bucuma	222	10	pathways	pathway	NNS
cord-257197-i9bucuma	222	11	to	to	TO
cord-257197-i9bucuma	222	12	internalize	internalize	VB
cord-257197-i9bucuma	222	13	peptide	peptide	JJ
cord-257197-i9bucuma	222	14	bilayer	bilayer	NN
cord-257197-i9bucuma	222	15	coated	coat	VBD
cord-257197-i9bucuma	222	16	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	222	17	in	in	IN
cord-257197-i9bucuma	222	18	a	a	DT
cord-257197-i9bucuma	222	19	time	time	NN
cord-257197-i9bucuma	222	20	dependent	dependent	JJ
cord-257197-i9bucuma	222	21	manner	manner	NN
cord-257197-i9bucuma	222	22	.	.	.
cord-257197-i9bucuma	223	1	71	71	CD
cord-257197-i9bucuma	224	1	The	the	DT
cord-257197-i9bucuma	224	2	surface	surface	NN
cord-257197-i9bucuma	224	3	composition	composition	NN
cord-257197-i9bucuma	224	4	plays	play	VBZ
cord-257197-i9bucuma	224	5	a	a	DT
cord-257197-i9bucuma	224	6	crucial	crucial	JJ
cord-257197-i9bucuma	224	7	role	role	NN
cord-257197-i9bucuma	224	8	since	since	IN
cord-257197-i9bucuma	224	9	they	-PRON-	PRP
cord-257197-i9bucuma	224	10	may	may	MD
cord-257197-i9bucuma	224	11	also	also	RB
cord-257197-i9bucuma	224	12	help	help	VB
cord-257197-i9bucuma	224	13	in	in	IN
cord-257197-i9bucuma	224	14	endosomal	endosomal	NNP
cord-257197-i9bucuma	224	15	escape	escape	VB
cord-257197-i9bucuma	224	16	as	as	IN
cord-257197-i9bucuma	224	17	observed	observe	VBN
cord-257197-i9bucuma	224	18	for	for	IN
cord-257197-i9bucuma	224	19	highly	highly	RB
cord-257197-i9bucuma	224	20	cationic	cationic	JJ
cord-257197-i9bucuma	224	21	NPs	NPs	NNPS
cord-257197-i9bucuma	224	22	.	.	.
cord-257197-i9bucuma	225	1	70	70	CD
cord-257197-i9bucuma	225	2	,	,	,
cord-257197-i9bucuma	225	3	139	139	CD
cord-257197-i9bucuma	225	4	Different	different	JJ
cord-257197-i9bucuma	225	5	cell	cell	NN
cord-257197-i9bucuma	225	6	types	type	NNS
cord-257197-i9bucuma	225	7	may	may	MD
cord-257197-i9bucuma	225	8	use	use	VB
cord-257197-i9bucuma	225	9	different	different	JJ
cord-257197-i9bucuma	225	10	endocytic	endocytic	JJ
cord-257197-i9bucuma	225	11	pathways	pathway	NNS
cord-257197-i9bucuma	225	12	for	for	IN
cord-257197-i9bucuma	225	13	the	the	DT
cord-257197-i9bucuma	225	14	uptake	uptake	NN
cord-257197-i9bucuma	225	15	of	of	IN
cord-257197-i9bucuma	225	16	the	the	DT
cord-257197-i9bucuma	225	17	same	same	JJ
cord-257197-i9bucuma	225	18	NPs	NPs	NNP
cord-257197-i9bucuma	225	19	140	140	CD
cord-257197-i9bucuma	225	20	and	and	CC
cord-257197-i9bucuma	225	21	a	a	DT
cord-257197-i9bucuma	225	22	single	single	JJ
cord-257197-i9bucuma	225	23	cell	cell	NN
cord-257197-i9bucuma	225	24	type	type	NN
cord-257197-i9bucuma	225	25	may	may	MD
cord-257197-i9bucuma	225	26	use	use	VB
cord-257197-i9bucuma	225	27	multiple	multiple	JJ
cord-257197-i9bucuma	225	28	pathways	pathway	NNS
cord-257197-i9bucuma	225	29	for	for	IN
cord-257197-i9bucuma	225	30	the	the	DT
cord-257197-i9bucuma	225	31	uptake	uptake	NN
cord-257197-i9bucuma	225	32	of	of	IN
cord-257197-i9bucuma	225	33	NPs	NPs	NNPS
cord-257197-i9bucuma	225	34	.	.	.
cord-257197-i9bucuma	226	1	71	71	CD
cord-257197-i9bucuma	226	2	Srijampa	Srijampa	NNP
cord-257197-i9bucuma	226	3	et	et	NNP
cord-257197-i9bucuma	226	4	al	al	NNP
cord-257197-i9bucuma	226	5	.	.	.
cord-257197-i9bucuma	227	1	141	141	CD
cord-257197-i9bucuma	227	2	identified	identify	VBD
cord-257197-i9bucuma	227	3	that	that	IN
cord-257197-i9bucuma	227	4	monocytes	monocyte	NNS
cord-257197-i9bucuma	227	5	and	and	CC
cord-257197-i9bucuma	227	6	macrophages	macrophage	NNS
cord-257197-i9bucuma	227	7	generally	generally	RB
cord-257197-i9bucuma	227	8	studied	study	VBN
cord-257197-i9bucuma	227	9	for	for	IN
cord-257197-i9bucuma	227	10	their	-PRON-	PRP$
cord-257197-i9bucuma	227	11	phagocytic	phagocytic	JJ
cord-257197-i9bucuma	227	12	response	response	NN
cord-257197-i9bucuma	227	13	may	may	MD
cord-257197-i9bucuma	227	14	also	also	RB
cord-257197-i9bucuma	227	15	use	use	VB
cord-257197-i9bucuma	227	16	other	other	JJ
cord-257197-i9bucuma	227	17	endocytosis	endocytosis	NN
cord-257197-i9bucuma	227	18	pathways	pathway	NNS
cord-257197-i9bucuma	227	19	alongside	alongside	IN
cord-257197-i9bucuma	227	20	phagocytosis	phagocytosis	NN
cord-257197-i9bucuma	227	21	for	for	IN
cord-257197-i9bucuma	227	22	NPs	NPs	NNP
cord-257197-i9bucuma	227	23	uptake	uptake	NN
cord-257197-i9bucuma	227	24	.	.	.
cord-257197-i9bucuma	228	1	B.End	B.End	NNP
cord-257197-i9bucuma	228	2	endothelial	endothelial	JJ
cord-257197-i9bucuma	228	3	cells	cell	NNS
cord-257197-i9bucuma	228	4	internalized	internalize	VBD
cord-257197-i9bucuma	228	5	more	more	JJR
cord-257197-i9bucuma	228	6	of	of	IN
cord-257197-i9bucuma	228	7	the	the	DT
cord-257197-i9bucuma	228	8	negatively	negatively	RB
cord-257197-i9bucuma	228	9	charged	charge	VBN
cord-257197-i9bucuma	228	10	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	228	11	in	in	IN
cord-257197-i9bucuma	228	12	comparison	comparison	NN
cord-257197-i9bucuma	228	13	to	to	IN
cord-257197-i9bucuma	228	14	epithelial	epithelial	JJ
cord-257197-i9bucuma	228	15	cells	cell	NNS
cord-257197-i9bucuma	228	16	,	,	,
cord-257197-i9bucuma	228	17	using	use	VBG
cord-257197-i9bucuma	228	18	CvME	CvME	NNP
cord-257197-i9bucuma	228	19	,	,	,
cord-257197-i9bucuma	228	20	which	which	WDT
cord-257197-i9bucuma	228	21	was	be	VBD
cord-257197-i9bucuma	228	22	enhanced	enhance	VBN
cord-257197-i9bucuma	228	23	in	in	IN
cord-257197-i9bucuma	228	24	the	the	DT
cord-257197-i9bucuma	228	25	endothelial	endothelial	JJ
cord-257197-i9bucuma	228	26	cells	cell	NNS
cord-257197-i9bucuma	228	27	since	since	IN
cord-257197-i9bucuma	228	28	they	-PRON-	PRP
cord-257197-i9bucuma	228	29	overexpressed	overexpresse	VBD
cord-257197-i9bucuma	228	30	the	the	DT
cord-257197-i9bucuma	228	31	caveolin-1	caveolin-1	NNP
cord-257197-i9bucuma	228	32	J	J	NNP
cord-257197-i9bucuma	228	33	o	o	NN
cord-257197-i9bucuma	228	34	u	u	NN
cord-257197-i9bucuma	228	35	r	r	NN
cord-257197-i9bucuma	228	36	n	n	NN
cord-257197-i9bucuma	228	37	a	a	DT
cord-257197-i9bucuma	228	38	l	l	NN
cord-257197-i9bucuma	228	39	P	p	NN
cord-257197-i9bucuma	228	40	r	r	NN
cord-257197-i9bucuma	228	41	e	e	NN
cord-257197-i9bucuma	228	42	-p	-p	NN
cord-257197-i9bucuma	228	43	r	r	NN
cord-257197-i9bucuma	228	44	o	o	NN
cord-257197-i9bucuma	229	1	o	o	UH
cord-257197-i9bucuma	229	2	f	f	NNP
cord-257197-i9bucuma	229	3	NPs	NPs	NNP
cord-257197-i9bucuma	229	4	can	can	MD
cord-257197-i9bucuma	229	5	elicit	elicit	VB
cord-257197-i9bucuma	229	6	an	an	DT
cord-257197-i9bucuma	229	7	immune	immune	JJ
cord-257197-i9bucuma	229	8	response	response	NN
cord-257197-i9bucuma	229	9	by	by	IN
cord-257197-i9bucuma	229	10	interfering	interfere	VBG
cord-257197-i9bucuma	229	11	and	and	CC
cord-257197-i9bucuma	229	12	interacting	interact	VBG
cord-257197-i9bucuma	229	13	with	with	IN
cord-257197-i9bucuma	229	14	intracellular	intracellular	JJ
cord-257197-i9bucuma	229	15	signaling	signal	VBG
cord-257197-i9bucuma	229	16	pathways	pathway	NNS
cord-257197-i9bucuma	229	17	directly	directly	RB
cord-257197-i9bucuma	229	18	or	or	CC
cord-257197-i9bucuma	229	19	indirectly	indirectly	RB
cord-257197-i9bucuma	229	20	via	via	IN
cord-257197-i9bucuma	229	21	the	the	DT
cord-257197-i9bucuma	229	22	reactive	reactive	JJ
cord-257197-i9bucuma	229	23	oxygen	oxygen	NN
cord-257197-i9bucuma	229	24	and	and	CC
cord-257197-i9bucuma	229	25	nitrogen	nitrogen	NN
cord-257197-i9bucuma	229	26	species	specie	NNS
cord-257197-i9bucuma	229	27	produced	produce	VBN
cord-257197-i9bucuma	229	28	.	.	.
cord-257197-i9bucuma	230	1	For	for	IN
cord-257197-i9bucuma	230	2	example	example	NN
cord-257197-i9bucuma	230	3	,	,	,
cord-257197-i9bucuma	230	4	the	the	DT
cord-257197-i9bucuma	230	5	transition	transition	NN
cord-257197-i9bucuma	230	6	metals	metal	NNS
cord-257197-i9bucuma	230	7	on	on	IN
cord-257197-i9bucuma	230	8	the	the	DT
cord-257197-i9bucuma	230	9	surface	surface	NN
cord-257197-i9bucuma	230	10	of	of	IN
cord-257197-i9bucuma	230	11	NPs	NPs	NNPS
cord-257197-i9bucuma	230	12	or	or	CC
cord-257197-i9bucuma	230	13	in	in	IN
cord-257197-i9bucuma	230	14	SPIONs	spion	NNS
cord-257197-i9bucuma	230	15	generate	generate	VBP
cord-257197-i9bucuma	230	16	ROS	ROS	NNP
cord-257197-i9bucuma	230	17	as	as	IN
cord-257197-i9bucuma	230	18	described	describe	VBN
cord-257197-i9bucuma	230	19	previously	previously	RB
cord-257197-i9bucuma	230	20	,	,	,
cord-257197-i9bucuma	230	21	which	which	WDT
cord-257197-i9bucuma	230	22	triggers	trigger	VBZ
cord-257197-i9bucuma	230	23	a	a	DT
cord-257197-i9bucuma	230	24	pro	pro	JJ
cord-257197-i9bucuma	230	25	-	-	JJ
cord-257197-i9bucuma	230	26	inflammatory	inflammatory	JJ
cord-257197-i9bucuma	230	27	response	response	NN
cord-257197-i9bucuma	230	28	.	.	.
cord-257197-i9bucuma	231	1	147	147	CD
cord-257197-i9bucuma	231	2	 	 	_SP
cord-257197-i9bucuma	232	1	The	the	DT
cord-257197-i9bucuma	232	2	NPs	NPs	NNP
cord-257197-i9bucuma	232	3	bio	bio	NN
cord-257197-i9bucuma	232	4	-	-	HYPH
cord-257197-i9bucuma	232	5	interactions	interaction	NNS
cord-257197-i9bucuma	232	6	in	in	IN
cord-257197-i9bucuma	232	7	the	the	DT
cord-257197-i9bucuma	232	8	complex	complex	NN
cord-257197-i9bucuma	232	9	in	in	IN
cord-257197-i9bucuma	232	10	vivo	vivo	NN
cord-257197-i9bucuma	232	11	environment	environment	NN
cord-257197-i9bucuma	232	12	are	be	VBP
cord-257197-i9bucuma	232	13	dependent	dependent	JJ
cord-257197-i9bucuma	232	14	on	on	IN
cord-257197-i9bucuma	232	15	their	-PRON-	PRP$
cord-257197-i9bucuma	232	16	physicochemical	physicochemical	JJ
cord-257197-i9bucuma	232	17	properties	property	NNS
cord-257197-i9bucuma	232	18	,	,	,
cord-257197-i9bucuma	232	19	contributing	contribute	VBG
cord-257197-i9bucuma	232	20	to	to	IN
cord-257197-i9bucuma	232	21	their	-PRON-	PRP$
cord-257197-i9bucuma	232	22	translocation	translocation	NN
cord-257197-i9bucuma	232	23	to	to	IN
cord-257197-i9bucuma	232	24	the	the	DT
cord-257197-i9bucuma	232	25	different	different	JJ
cord-257197-i9bucuma	232	26	organs	organ	NNS
cord-257197-i9bucuma	232	27	and	and	CC
cord-257197-i9bucuma	232	28	tissues	tissue	NNS
cord-257197-i9bucuma	232	29	and	and	CC
cord-257197-i9bucuma	232	30	ultimate	ultimate	JJ
cord-257197-i9bucuma	232	31	clearance	clearance	NN
cord-257197-i9bucuma	232	32	.	.	.
cord-257197-i9bucuma	233	1	97	97	CD
cord-257197-i9bucuma	233	2	,	,	,
cord-257197-i9bucuma	233	3	156	156	CD
cord-257197-i9bucuma	233	4	Therefore	therefore	RB
cord-257197-i9bucuma	233	5	,	,	,
cord-257197-i9bucuma	233	6	it	-PRON-	PRP
cord-257197-i9bucuma	233	7	is	be	VBZ
cord-257197-i9bucuma	233	8	vital	vital	JJ
cord-257197-i9bucuma	233	9	to	to	TO
cord-257197-i9bucuma	233	10	discern	discern	VB
cord-257197-i9bucuma	233	11	the	the	DT
cord-257197-i9bucuma	233	12	relationship	relationship	NN
cord-257197-i9bucuma	233	13	between	between	IN
cord-257197-i9bucuma	233	14	the	the	DT
cord-257197-i9bucuma	233	15	NPs	NPs	NNPS
cord-257197-i9bucuma	233	16	and	and	CC
cord-257197-i9bucuma	233	17	the	the	DT
cord-257197-i9bucuma	233	18	interactions	interaction	NNS
cord-257197-i9bucuma	233	19	with	with	IN
cord-257197-i9bucuma	233	20	endogenous	endogenous	JJ
cord-257197-i9bucuma	233	21	molecules	molecule	NNS
cord-257197-i9bucuma	233	22	that	that	WDT
cord-257197-i9bucuma	233	23	influence	influence	VBP
cord-257197-i9bucuma	233	24	their	-PRON-	PRP$
cord-257197-i9bucuma	233	25	biodistribution	biodistribution	NN
cord-257197-i9bucuma	233	26	.	.	.
cord-257197-i9bucuma	234	1	In	in	IN
cord-257197-i9bucuma	234	2	this	this	DT
cord-257197-i9bucuma	234	3	section	section	NN
cord-257197-i9bucuma	234	4	,	,	,
cord-257197-i9bucuma	234	5	The	the	DT
cord-257197-i9bucuma	234	6	route	route	NN
cord-257197-i9bucuma	234	7	of	of	IN
cord-257197-i9bucuma	234	8	administration	administration	NN
cord-257197-i9bucuma	234	9	has	have	VBZ
cord-257197-i9bucuma	234	10	an	an	DT
cord-257197-i9bucuma	234	11	obvious	obvious	JJ
cord-257197-i9bucuma	234	12	role	role	NN
cord-257197-i9bucuma	234	13	to	to	TO
cord-257197-i9bucuma	234	14	play	play	VB
cord-257197-i9bucuma	234	15	on	on	IN
cord-257197-i9bucuma	234	16	the	the	DT
cord-257197-i9bucuma	234	17	tissue	tissue	NN
cord-257197-i9bucuma	234	18	distribution	distribution	NN
cord-257197-i9bucuma	234	19	which	which	WDT
cord-257197-i9bucuma	234	20	is	be	VBZ
cord-257197-i9bucuma	234	21	generally	generally	RB
cord-257197-i9bucuma	234	22	chosen	choose	VBN
cord-257197-i9bucuma	234	23	based	base	VBN
cord-257197-i9bucuma	234	24	on	on	IN
cord-257197-i9bucuma	234	25	the	the	DT
cord-257197-i9bucuma	234	26	end	end	NN
cord-257197-i9bucuma	234	27	application	application	NN
cord-257197-i9bucuma	234	28	of	of	IN
cord-257197-i9bucuma	234	29	NPs	NPs	NNPS
cord-257197-i9bucuma	234	30	.	.	.
cord-257197-i9bucuma	235	1	However	however	RB
cord-257197-i9bucuma	235	2	,	,	,
cord-257197-i9bucuma	235	3	i.v	i.v	NNP
cord-257197-i9bucuma	235	4	.	.	.
cord-257197-i9bucuma	235	5	injections	injection	NNS
cord-257197-i9bucuma	235	6	are	be	VBP
cord-257197-i9bucuma	235	7	used	use	VBN
cord-257197-i9bucuma	235	8	more	more	RBR
cord-257197-i9bucuma	235	9	commonly	commonly	RB
cord-257197-i9bucuma	235	10	since	since	IN
cord-257197-i9bucuma	235	11	they	-PRON-	PRP
cord-257197-i9bucuma	235	12	can	can	MD
cord-257197-i9bucuma	235	13	provide	provide	VB
cord-257197-i9bucuma	235	14	a	a	DT
cord-257197-i9bucuma	235	15	near	near	JJ
cord-257197-i9bucuma	235	16	instantaneous	instantaneous	JJ
cord-257197-i9bucuma	235	17	response	response	NN
cord-257197-i9bucuma	235	18	and	and	CC
cord-257197-i9bucuma	235	19	is	be	VBZ
cord-257197-i9bucuma	235	20	suitable	suitable	JJ
cord-257197-i9bucuma	235	21	for	for	IN
cord-257197-i9bucuma	235	22	delivery	delivery	NN
cord-257197-i9bucuma	235	23	of	of	IN
cord-257197-i9bucuma	235	24	materials	material	NNS
cord-257197-i9bucuma	235	25	that	that	WDT
cord-257197-i9bucuma	235	26	can	can	MD
cord-257197-i9bucuma	235	27	not	not	RB
cord-257197-i9bucuma	235	28	be	be	VB
cord-257197-i9bucuma	235	29	absorbed	absorb	VBN
cord-257197-i9bucuma	235	30	efficiently	efficiently	RB
cord-257197-i9bucuma	235	31	or	or	CC
cord-257197-i9bucuma	235	32	that	that	DT
cord-257197-i9bucuma	235	33	can	can	MD
cord-257197-i9bucuma	235	34	undergo	undergo	VB
cord-257197-i9bucuma	235	35	proteolytic	proteolytic	JJ
cord-257197-i9bucuma	235	36	or	or	CC
cord-257197-i9bucuma	235	37	pH	pH	NNP
cord-257197-i9bucuma	235	38	disruption	disruption	NN
cord-257197-i9bucuma	235	39	.	.	.
cord-257197-i9bucuma	236	1	Another	another	DT
cord-257197-i9bucuma	236	2	major	major	JJ
cord-257197-i9bucuma	236	3	advantage	advantage	NN
cord-257197-i9bucuma	236	4	of	of	IN
cord-257197-i9bucuma	236	5	i.v	i.v	NNP
cord-257197-i9bucuma	236	6	.	.	.
cord-257197-i9bucuma	236	7	injections	injection	NNS
cord-257197-i9bucuma	236	8	is	be	VBZ
cord-257197-i9bucuma	236	9	the	the	DT
cord-257197-i9bucuma	236	10	increased	increase	VBN
cord-257197-i9bucuma	236	11	bioavailability	bioavailability	NN
cord-257197-i9bucuma	236	12	of	of	IN
cord-257197-i9bucuma	236	13	drugs	drug	NNS
cord-257197-i9bucuma	236	14	.	.	.
cord-257197-i9bucuma	237	1	157	157	CD
cord-257197-i9bucuma	238	1	The	the	DT
cord-257197-i9bucuma	238	2	animal	animal	NN
cord-257197-i9bucuma	238	3	model	model	NN
cord-257197-i9bucuma	238	4	selected	select	VBN
cord-257197-i9bucuma	238	5	for	for	IN
cord-257197-i9bucuma	238	6	a	a	DT
cord-257197-i9bucuma	238	7	particular	particular	JJ
cord-257197-i9bucuma	238	8	study	study	NN
cord-257197-i9bucuma	238	9	may	may	MD
cord-257197-i9bucuma	238	10	influence	influence	VB
cord-257197-i9bucuma	238	11	the	the	DT
cord-257197-i9bucuma	238	12	administration	administration	NN
cord-257197-i9bucuma	238	13	route	route	NN
cord-257197-i9bucuma	238	14	.	.	.
cord-257197-i9bucuma	239	1	158	158	CD
cord-257197-i9bucuma	239	2	Intramuscular	intramuscular	JJ
cord-257197-i9bucuma	239	3	delivery	delivery	NN
cord-257197-i9bucuma	239	4	in	in	IN
cord-257197-i9bucuma	239	5	mice	mice	NN
cord-257197-i9bucuma	239	6	is	be	VBZ
cord-257197-i9bucuma	239	7	generally	generally	RB
cord-257197-i9bucuma	239	8	not	not	RB
cord-257197-i9bucuma	239	9	recommended	recommend	VBN
cord-257197-i9bucuma	239	10	as	as	IN
cord-257197-i9bucuma	239	11	their	-PRON-	PRP$
cord-257197-i9bucuma	239	12	muscles	muscle	NNS
cord-257197-i9bucuma	239	13	are	be	VBP
cord-257197-i9bucuma	239	14	small	small	JJ
cord-257197-i9bucuma	239	15	,	,	,
cord-257197-i9bucuma	239	16	making	make	VBG
cord-257197-i9bucuma	239	17	it	-PRON-	PRP
cord-257197-i9bucuma	239	18	difficult	difficult	JJ
cord-257197-i9bucuma	239	19	to	to	TO
cord-257197-i9bucuma	239	20	get	get	VB
cord-257197-i9bucuma	239	21	reproducible	reproducible	JJ
cord-257197-i9bucuma	239	22	results	result	NNS
cord-257197-i9bucuma	239	23	.	.	.
cord-257197-i9bucuma	240	1	159	159	CD
cord-257197-i9bucuma	241	1	The	the	DT
cord-257197-i9bucuma	241	2	genetic	genetic	JJ
cord-257197-i9bucuma	241	3	background	background	NN
cord-257197-i9bucuma	241	4	of	of	IN
cord-257197-i9bucuma	241	5	animals	animal	NNS
cord-257197-i9bucuma	241	6	will	will	MD
cord-257197-i9bucuma	241	7	also	also	RB
cord-257197-i9bucuma	241	8	show	show	VB
cord-257197-i9bucuma	241	9	variations	variation	NNS
cord-257197-i9bucuma	241	10	in	in	IN
cord-257197-i9bucuma	241	11	NPs	NPs	NNP
cord-257197-i9bucuma	241	12	interactions	interaction	NNS
cord-257197-i9bucuma	241	13	due	due	JJ
cord-257197-i9bucuma	241	14	to	to	IN
cord-257197-i9bucuma	241	15	differences	difference	NNS
cord-257197-i9bucuma	241	16	in	in	IN
cord-257197-i9bucuma	241	17	their	-PRON-	PRP$
cord-257197-i9bucuma	241	18	response	response	NN
cord-257197-i9bucuma	241	19	to	to	IN
cord-257197-i9bucuma	241	20	foreign	foreign	JJ
cord-257197-i9bucuma	241	21	molecules	molecule	NNS
cord-257197-i9bucuma	241	22	.	.	.
cord-257197-i9bucuma	242	1	The	the	DT
cord-257197-i9bucuma	242	2	C57BL/6	C57BL/6	NNPS
cord-257197-i9bucuma	242	3	and	and	CC
cord-257197-i9bucuma	242	4	the	the	DT
cord-257197-i9bucuma	242	5	BALB	BALB	NNP
cord-257197-i9bucuma	242	6	/	/	SYM
cord-257197-i9bucuma	242	7	c	c	NN
cord-257197-i9bucuma	242	8	mice	mouse	NNS
cord-257197-i9bucuma	242	9	,	,	,
cord-257197-i9bucuma	242	10	for	for	IN
cord-257197-i9bucuma	242	11	example	example	NN
cord-257197-i9bucuma	242	12	,	,	,
cord-257197-i9bucuma	242	13	fundamentally	fundamentally	RB
cord-257197-i9bucuma	242	14	exhibit	exhibit	VB
cord-257197-i9bucuma	242	15	different	different	JJ
cord-257197-i9bucuma	242	16	immune	immune	JJ
cord-257197-i9bucuma	242	17	responses	response	NNS
cord-257197-i9bucuma	242	18	that	that	WDT
cord-257197-i9bucuma	242	19	could	could	MD
cord-257197-i9bucuma	242	20	affect	affect	VB
cord-257197-i9bucuma	242	21	J	J	NNP
cord-257197-i9bucuma	242	22	o	o	NN
cord-257197-i9bucuma	242	23	u	u	NN
cord-257197-i9bucuma	242	24	r	r	NN
cord-257197-i9bucuma	242	25	n	n	NN
cord-257197-i9bucuma	243	1	a	a	DT
cord-257197-i9bucuma	243	2	l	l	NN
cord-257197-i9bucuma	243	3	P	p	NN
cord-257197-i9bucuma	243	4	r	r	NN
cord-257197-i9bucuma	243	5	e	e	NN
cord-257197-i9bucuma	243	6	-p	-p	NN
cord-257197-i9bucuma	243	7	r	r	NN
cord-257197-i9bucuma	243	8	o	o	NN
cord-257197-i9bucuma	243	9	o	o	NN
cord-257197-i9bucuma	243	10	f	f	XX
cord-257197-i9bucuma	243	11	their	-PRON-	PRP$
cord-257197-i9bucuma	243	12	adaptive	adaptive	JJ
cord-257197-i9bucuma	243	13	immunity	immunity	NN
cord-257197-i9bucuma	243	14	.	.	.
cord-257197-i9bucuma	244	1	C57Bl/6	C57Bl/6	NNP
cord-257197-i9bucuma	244	2	and	and	CC
cord-257197-i9bucuma	244	3	BALB	BALB	NNP
cord-257197-i9bucuma	244	4	/	/	SYM
cord-257197-i9bucuma	244	5	c	c	NNP
cord-257197-i9bucuma	244	6	are	be	VBP
cord-257197-i9bucuma	244	7	prototypical	prototypical	JJ
cord-257197-i9bucuma	244	8	,	,	,
cord-257197-i9bucuma	244	9	Th1	th1	NN
cord-257197-i9bucuma	244	10	and	and	CC
cord-257197-i9bucuma	244	11	Th2	th2	CD
cord-257197-i9bucuma	244	12	type	type	NN
cord-257197-i9bucuma	244	13	mouse	mouse	NN
cord-257197-i9bucuma	244	14	strains	strain	NNS
cord-257197-i9bucuma	244	15	,	,	,
cord-257197-i9bucuma	244	16	respectively	respectively	RB
cord-257197-i9bucuma	244	17	,	,	,
cord-257197-i9bucuma	244	18	and	and	CC
cord-257197-i9bucuma	244	19	therefore	therefore	RB
cord-257197-i9bucuma	244	20	can	can	MD
cord-257197-i9bucuma	244	21	have	have	VB
cord-257197-i9bucuma	244	22	an	an	DT
cord-257197-i9bucuma	244	23	altered	altered	JJ
cord-257197-i9bucuma	244	24	response	response	NN
cord-257197-i9bucuma	244	25	to	to	IN
cord-257197-i9bucuma	244	26	NPs	NPs	NNP
cord-257197-i9bucuma	244	27	.	.	.
cord-257197-i9bucuma	245	1	160	160	CD
cord-257197-i9bucuma	246	1	When	when	WRB
cord-257197-i9bucuma	246	2	NPs	NPs	NNP
cord-257197-i9bucuma	246	3	are	be	VBP
cord-257197-i9bucuma	246	4	administered	administer	VBN
cord-257197-i9bucuma	246	5	,	,	,
cord-257197-i9bucuma	246	6	they	-PRON-	PRP
cord-257197-i9bucuma	246	7	have	have	VBP
cord-257197-i9bucuma	246	8	to	to	TO
cord-257197-i9bucuma	246	9	cross	cross	VB
cord-257197-i9bucuma	246	10	various	various	JJ
cord-257197-i9bucuma	246	11	hurdles	hurdle	NNS
cord-257197-i9bucuma	246	12	before	before	IN
cord-257197-i9bucuma	246	13	they	-PRON-	PRP
cord-257197-i9bucuma	246	14	reach	reach	VBP
cord-257197-i9bucuma	246	15	the	the	DT
cord-257197-i9bucuma	246	16	There	there	EX
cord-257197-i9bucuma	246	17	has	have	VBZ
cord-257197-i9bucuma	246	18	been	be	VBN
cord-257197-i9bucuma	246	19	an	an	DT
cord-257197-i9bucuma	246	20	increase	increase	NN
cord-257197-i9bucuma	246	21	in	in	IN
cord-257197-i9bucuma	246	22	studies	study	NNS
cord-257197-i9bucuma	246	23	exploring	explore	VBG
cord-257197-i9bucuma	246	24	intradermal	intradermal	JJ
cord-257197-i9bucuma	246	25	delivery	delivery	NN
cord-257197-i9bucuma	246	26	using	use	VBG
cord-257197-i9bucuma	246	27	microneedles	microneedles	NNP
cord-257197-i9bucuma	246	28	as	as	IN
cord-257197-i9bucuma	246	29	it	-PRON-	PRP
cord-257197-i9bucuma	246	30	is	be	VBZ
cord-257197-i9bucuma	246	31	minimally	minimally	RB
cord-257197-i9bucuma	246	32	invasive	invasive	JJ
cord-257197-i9bucuma	246	33	.	.	.
cord-257197-i9bucuma	247	1	172	172	CD
cord-257197-i9bucuma	247	2	Dur	Dur	NNP
cord-257197-i9bucuma	247	3	et	et	FW
cord-257197-i9bucuma	247	4	al	al	NNP
cord-257197-i9bucuma	247	5	.	.	.
cord-257197-i9bucuma	248	1	173	173	CD
cord-257197-i9bucuma	248	2	 	 	_SP
cord-257197-i9bucuma	249	1	In	in	IN
cord-257197-i9bucuma	249	2	vitro	vitro	FW
cord-257197-i9bucuma	249	3	studies	study	NNS
cord-257197-i9bucuma	249	4	can	can	MD
cord-257197-i9bucuma	249	5	guide	guide	VB
cord-257197-i9bucuma	249	6	one	one	CD
cord-257197-i9bucuma	249	7	in	in	IN
cord-257197-i9bucuma	249	8	explaining	explain	VBG
cord-257197-i9bucuma	249	9	the	the	DT
cord-257197-i9bucuma	249	10	effects	effect	NNS
cord-257197-i9bucuma	249	11	of	of	IN
cord-257197-i9bucuma	249	12	NPs	NPs	NNPS
cord-257197-i9bucuma	249	13	in	in	IN
cord-257197-i9bucuma	249	14	vivo	vivo	NNP
cord-257197-i9bucuma	249	15	.	.	.
cord-257197-i9bucuma	250	1	For	for	IN
cord-257197-i9bucuma	250	2	instance	instance	NN
cord-257197-i9bucuma	250	3	,	,	,
cord-257197-i9bucuma	250	4	ROS	ROS	NNP
cord-257197-i9bucuma	250	5	and	and	CC
cord-257197-i9bucuma	250	6	RNS	RNS	NNP
cord-257197-i9bucuma	250	7	generated	generate	VBD
cord-257197-i9bucuma	250	8	in	in	IN
cord-257197-i9bucuma	250	9	response	response	NN
cord-257197-i9bucuma	250	10	to	to	IN
cord-257197-i9bucuma	250	11	NPs	NPs	NNP
cord-257197-i9bucuma	250	12	activates	activate	VBZ
cord-257197-i9bucuma	250	13	the	the	DT
cord-257197-i9bucuma	250	14	cells	cell	NNS
cord-257197-i9bucuma	250	15	and	and	CC
cord-257197-i9bucuma	250	16	induces	induce	VBZ
cord-257197-i9bucuma	250	17	secretion	secretion	NN
cord-257197-i9bucuma	250	18	of	of	IN
cord-257197-i9bucuma	250	19	cytokines	cytokine	NNS
cord-257197-i9bucuma	250	20	/	/	SYM
cord-257197-i9bucuma	250	21	chemokines	chemokine	NNS
cord-257197-i9bucuma	250	22	.	.	.
cord-257197-i9bucuma	251	1	(	(	-LRB-
cord-257197-i9bucuma	251	2	Fig	Fig	NNP
cord-257197-i9bucuma	251	3	.	.	NNP
cord-257197-i9bucuma	251	4	4	4	CD
cord-257197-i9bucuma	251	5	)	)	-RRB-
cord-257197-i9bucuma	252	1	This	this	DT
cord-257197-i9bucuma	252	2	leads	lead	VBZ
cord-257197-i9bucuma	252	3	further	further	RB
cord-257197-i9bucuma	252	4	to	to	IN
cord-257197-i9bucuma	252	5	the	the	DT
cord-257197-i9bucuma	252	6	infiltration	infiltration	NN
cord-257197-i9bucuma	252	7	of	of	IN
cord-257197-i9bucuma	252	8	immune	immune	JJ
cord-257197-i9bucuma	252	9	cells	cell	NNS
cord-257197-i9bucuma	252	10	,	,	,
cord-257197-i9bucuma	252	11	which	which	WDT
cord-257197-i9bucuma	252	12	may	may	MD
cord-257197-i9bucuma	252	13	cause	cause	VB
cord-257197-i9bucuma	252	14	tissue	tissue	NN
cord-257197-i9bucuma	252	15	necrosis	necrosis	NN
cord-257197-i9bucuma	252	16	or	or	CC
cord-257197-i9bucuma	252	17	induce	induce	VB
cord-257197-i9bucuma	252	18	apoptosis	apoptosis	NN
cord-257197-i9bucuma	252	19	of	of	IN
cord-257197-i9bucuma	252	20	cells	cell	NNS
cord-257197-i9bucuma	252	21	causing	cause	VBG
cord-257197-i9bucuma	252	22	organ	organ	NN
cord-257197-i9bucuma	252	23	damage	damage	NN
cord-257197-i9bucuma	252	24	.	.	.
cord-257197-i9bucuma	253	1	Thus	thus	RB
cord-257197-i9bucuma	253	2	,	,	,
cord-257197-i9bucuma	253	3	the	the	DT
cord-257197-i9bucuma	253	4	immune	immune	JJ
cord-257197-i9bucuma	253	5	response	response	NN
cord-257197-i9bucuma	253	6	to	to	IN
cord-257197-i9bucuma	253	7	the	the	DT
cord-257197-i9bucuma	253	8	NPs	NPs	NNPS
cord-257197-i9bucuma	253	9	can	can	MD
cord-257197-i9bucuma	253	10	lead	lead	VB
cord-257197-i9bucuma	253	11	to	to	IN
cord-257197-i9bucuma	253	12	a	a	DT
cord-257197-i9bucuma	253	13	cascade	cascade	NN
cord-257197-i9bucuma	253	14	of	of	IN
cord-257197-i9bucuma	253	15	events	event	NNS
cord-257197-i9bucuma	253	16	that	that	WDT
cord-257197-i9bucuma	253	17	induces	induce	VBZ
cord-257197-i9bucuma	253	18	toxicity	toxicity	NN
cord-257197-i9bucuma	253	19	.	.	.
cord-257197-i9bucuma	254	1	In	in	IN
cord-257197-i9bucuma	254	2	vivo	vivo	NN
cord-257197-i9bucuma	254	3	,	,	,
cord-257197-i9bucuma	254	4	toxicity	toxicity	NN
cord-257197-i9bucuma	254	5	is	be	VBZ
cord-257197-i9bucuma	254	6	determined	determine	VBN
cord-257197-i9bucuma	254	7	by	by	IN
cord-257197-i9bucuma	254	8	assessing	assess	VBG
cord-257197-i9bucuma	254	9	ultrastructural	ultrastructural	JJ
cord-257197-i9bucuma	254	10	changes	change	NNS
cord-257197-i9bucuma	254	11	in	in	IN
cord-257197-i9bucuma	254	12	the	the	DT
cord-257197-i9bucuma	254	13	tissues	tissue	NNS
cord-257197-i9bucuma	254	14	(	(	-LRB-
cord-257197-i9bucuma	254	15	Fig.3	Fig.3	NNP
cord-257197-i9bucuma	254	16	)	)	-RRB-
cord-257197-i9bucuma	254	17	,	,	,
cord-257197-i9bucuma	254	18	comparing	compare	VBG
cord-257197-i9bucuma	254	19	cytokine	cytokine	NN
cord-257197-i9bucuma	254	20	levels	level	NNS
cord-257197-i9bucuma	254	21	and	and	CC
cord-257197-i9bucuma	254	22	other	other	JJ
cord-257197-i9bucuma	254	23	molecular	molecular	JJ
cord-257197-i9bucuma	254	24	markers	marker	NNS
cord-257197-i9bucuma	254	25	in	in	IN
cord-257197-i9bucuma	254	26	serum	serum	NN
cord-257197-i9bucuma	254	27	and	and	CC
cord-257197-i9bucuma	254	28	analyzing	analyze	VBG
cord-257197-i9bucuma	254	29	blood	blood	NN
cord-257197-i9bucuma	254	30	cell	cell	NN
cord-257197-i9bucuma	254	31	counts	count	NNS
cord-257197-i9bucuma	254	32	(	(	-LRB-
cord-257197-i9bucuma	254	33	hematology	hematology	NN
cord-257197-i9bucuma	254	34	)	)	-RRB-
cord-257197-i9bucuma	254	35	171	171	CD
cord-257197-i9bucuma	254	36	injection	injection	NN
cord-257197-i9bucuma	254	37	.	.	.
cord-257197-i9bucuma	255	1	168	168	CD
cord-257197-i9bucuma	255	2	PEI	PEI	NNP
cord-257197-i9bucuma	255	3	-	-	HYPH
cord-257197-i9bucuma	255	4	FeONPs	FeONPs	NNP
cord-257197-i9bucuma	255	5	at	at	IN
cord-257197-i9bucuma	255	6	5	5	CD
cord-257197-i9bucuma	255	7	and	and	CC
cord-257197-i9bucuma	256	1	2.5	2.5	CD
cord-257197-i9bucuma	256	2	mg	mg	NNP
cord-257197-i9bucuma	256	3	/	/	SYM
cord-257197-i9bucuma	256	4	kg	kg	NN
cord-257197-i9bucuma	256	5	doses	dose	NNS
cord-257197-i9bucuma	256	6	were	be	VBD
cord-257197-i9bucuma	256	7	highly	highly	RB
cord-257197-i9bucuma	256	8	toxic	toxic	JJ
cord-257197-i9bucuma	256	9	to	to	IN
cord-257197-i9bucuma	256	10	mice	mouse	NNS
cord-257197-i9bucuma	256	11	leading	lead	VBG
cord-257197-i9bucuma	256	12	to	to	IN
cord-257197-i9bucuma	256	13	death	death	NN
cord-257197-i9bucuma	256	14	,	,	,
cord-257197-i9bucuma	256	15	but	but	CC
cord-257197-i9bucuma	256	16	a	a	DT
cord-257197-i9bucuma	256	17	dose	dose	NN
cord-257197-i9bucuma	256	18	of	of	IN
cord-257197-i9bucuma	256	19	1.5	1.5	CD
cord-257197-i9bucuma	256	20	mg	mg	NNP
cord-257197-i9bucuma	256	21	/	/	SYM
cord-257197-i9bucuma	256	22	kg	kg	NNP
cord-257197-i9bucuma	256	23	was	be	VBD
cord-257197-i9bucuma	256	24	well	well	RB
cord-257197-i9bucuma	256	25	tolerated	tolerate	VBN
cord-257197-i9bucuma	256	26	.	.	.
cord-257197-i9bucuma	257	1	99	99	CD
cord-257197-i9bucuma	258	1	J	J	NNP
cord-257197-i9bucuma	258	2	o	o	NN
cord-257197-i9bucuma	258	3	u	u	NN
cord-257197-i9bucuma	258	4	r	r	NN
cord-257197-i9bucuma	258	5	n	n	NN
cord-257197-i9bucuma	258	6	a	a	DT
cord-257197-i9bucuma	258	7	l	l	NN
cord-257197-i9bucuma	258	8	P	p	NN
cord-257197-i9bucuma	258	9	r	r	NN
cord-257197-i9bucuma	258	10	e	e	NN
cord-257197-i9bucuma	258	11	-p	-p	NN
cord-257197-i9bucuma	258	12	r	r	NN
cord-257197-i9bucuma	258	13	o	o	NN
cord-257197-i9bucuma	258	14	o	o	NN
cord-257197-i9bucuma	258	15	f	f	NN
cord-257197-i9bucuma	258	16	J	j	NN
cord-257197-i9bucuma	258	17	o	o	NN
cord-257197-i9bucuma	258	18	u	u	NN
cord-257197-i9bucuma	258	19	r	r	NN
cord-257197-i9bucuma	258	20	n	n	NN
cord-257197-i9bucuma	258	21	a	a	DT
cord-257197-i9bucuma	258	22	l	l	NN
cord-257197-i9bucuma	258	23	P	p	NN
cord-257197-i9bucuma	258	24	r	r	NN
cord-257197-i9bucuma	258	25	e	e	NN
cord-257197-i9bucuma	258	26	-p	-p	NN
cord-257197-i9bucuma	259	1	r	r	LS
cord-257197-i9bucuma	260	1	o	o	UH
cord-257197-i9bucuma	261	1	o	o	UH
cord-257197-i9bucuma	261	2	f	f	NNP
cord-257197-i9bucuma	262	1	This	this	DT
cord-257197-i9bucuma	262	2	may	may	MD
cord-257197-i9bucuma	262	3	also	also	RB
cord-257197-i9bucuma	262	4	lead	lead	VB
cord-257197-i9bucuma	262	5	to	to	IN
cord-257197-i9bucuma	262	6	metabolic	metabolic	JJ
cord-257197-i9bucuma	262	7	changes	change	NNS
cord-257197-i9bucuma	262	8	.	.	.
cord-257197-i9bucuma	263	1	Reactive	reactive	JJ
cord-257197-i9bucuma	263	2	nitrate	nitrate	NN
cord-257197-i9bucuma	263	3	species	specie	NNS
cord-257197-i9bucuma	263	4	(	(	-LRB-
cord-257197-i9bucuma	263	5	RNS	RNS	NNP
cord-257197-i9bucuma	263	6	)	)	-RRB-
cord-257197-i9bucuma	263	7	produced	produce	VBN
cord-257197-i9bucuma	263	8	mainly	mainly	RB
cord-257197-i9bucuma	263	9	by	by	IN
cord-257197-i9bucuma	263	10	immune	immune	JJ
cord-257197-i9bucuma	263	11	cells	cell	NNS
cord-257197-i9bucuma	263	12	such	such	JJ
cord-257197-i9bucuma	263	13	as	as	IN
cord-257197-i9bucuma	263	14	macrophages	macrophage	NNS
cord-257197-i9bucuma	263	15	and	and	CC
cord-257197-i9bucuma	263	16	neutrophils	neutrophil	NNS
cord-257197-i9bucuma	263	17	along	along	IN
cord-257197-i9bucuma	263	18	with	with	IN
cord-257197-i9bucuma	263	19	the	the	DT
cord-257197-i9bucuma	263	20	ROS	ROS	NNP
cord-257197-i9bucuma	263	21	are	be	VBP
cord-257197-i9bucuma	263	22	considered	consider	VBN
cord-257197-i9bucuma	263	23	to	to	TO
cord-257197-i9bucuma	263	24	be	be	VB
cord-257197-i9bucuma	263	25	indicators	indicator	NNS
cord-257197-i9bucuma	263	26	of	of	IN
cord-257197-i9bucuma	263	27	cellular	cellular	JJ
cord-257197-i9bucuma	263	28	activation	activation	NN
cord-257197-i9bucuma	263	29	.	.	.
cord-257197-i9bucuma	264	1	Altogether	altogether	RB
cord-257197-i9bucuma	264	2	,	,	,
cord-257197-i9bucuma	264	3	the	the	DT
cord-257197-i9bucuma	264	4	intracellular	intracellular	JJ
cord-257197-i9bucuma	264	5	changes	change	NNS
cord-257197-i9bucuma	264	6	may	may	MD
cord-257197-i9bucuma	264	7	cause	cause	VB
cord-257197-i9bucuma	264	8	cellular	cellular	JJ
cord-257197-i9bucuma	264	9	toxicity	toxicity	NN
cord-257197-i9bucuma	264	10	(	(	-LRB-
cord-257197-i9bucuma	264	11	iv	iv	LS
cord-257197-i9bucuma	264	12	)	)	-RRB-
cord-257197-i9bucuma	264	13	and	and	CC
cord-257197-i9bucuma	264	14	cause	cause	VB
cord-257197-i9bucuma	264	15	an	an	DT
cord-257197-i9bucuma	264	16	immune	immune	JJ
cord-257197-i9bucuma	264	17	response	response	NN
cord-257197-i9bucuma	264	18	by	by	IN
cord-257197-i9bucuma	264	19	inducing	induce	VBG
cord-257197-i9bucuma	264	20	changes	change	NNS
cord-257197-i9bucuma	264	21	in	in	IN
cord-257197-i9bucuma	264	22	cytokine	cytokine	NN
cord-257197-i9bucuma	264	23	and	and	CC
cord-257197-i9bucuma	264	24	chemokines	chemokine	NNS
cord-257197-i9bucuma	264	25	secretion	secretion	NN
cord-257197-i9bucuma	264	26	(	(	-LRB-
cord-257197-i9bucuma	264	27	v	v	NN
cord-257197-i9bucuma	264	28	)	)	-RRB-
cord-257197-i9bucuma	264	29	.	.	.
cord-257197-i9bucuma	265	1	NPs	NPs	NNP
cord-257197-i9bucuma	265	2	can	can	MD
cord-257197-i9bucuma	265	3	also	also	RB
cord-257197-i9bucuma	265	4	be	be	VB
cord-257197-i9bucuma	265	5	exocytosed	exocytose	VBN
cord-257197-i9bucuma	265	6	in	in	IN
cord-257197-i9bucuma	265	7	vesicles	vesicle	NNS
cord-257197-i9bucuma	265	8	called	call	VBN
cord-257197-i9bucuma	265	9	exosomes	exosome	NNS
cord-257197-i9bucuma	265	10	which	which	WDT
cord-257197-i9bucuma	265	11	may	may	MD
cord-257197-i9bucuma	265	12	be	be	VB
cord-257197-i9bucuma	265	13	inherently	inherently	RB
cord-257197-i9bucuma	265	14	targeted	target	VBN
cord-257197-i9bucuma	265	15	to	to	IN
cord-257197-i9bucuma	265	16	different	different	JJ
cord-257197-i9bucuma	265	17	tissues	tissue	NNS
cord-257197-i9bucuma	265	18	.	.	.
cord-257197-i9bucuma	266	1	Therefore	therefore	RB
cord-257197-i9bucuma	266	2	,	,	,
cord-257197-i9bucuma	266	3	a	a	DT
cord-257197-i9bucuma	266	4	cascade	cascade	NN
cord-257197-i9bucuma	266	5	of	of	IN
cord-257197-i9bucuma	266	6	events	event	NNS
cord-257197-i9bucuma	266	7	determines	determine	VBZ
cord-257197-i9bucuma	266	8	the	the	DT
cord-257197-i9bucuma	266	9	bioavailability	bioavailability	NN
cord-257197-i9bucuma	266	10	,	,	,
cord-257197-i9bucuma	266	11	clearance	clearance	NN
cord-257197-i9bucuma	266	12	,	,	,
cord-257197-i9bucuma	266	13	toxicity	toxicity	NN
cord-257197-i9bucuma	266	14	profile	profile	NN
cord-257197-i9bucuma	266	15	and	and	CC
cord-257197-i9bucuma	266	16	thus	thus	RB
cord-257197-i9bucuma	266	17	,	,	,
cord-257197-i9bucuma	266	18	the	the	DT
cord-257197-i9bucuma	266	19	net	net	JJ
cord-257197-i9bucuma	266	20	effect	effect	NN
cord-257197-i9bucuma	266	21	of	of	IN
cord-257197-i9bucuma	266	22	NPs	NPs	NNPS
cord-257197-i9bucuma	266	23	.	.	.
cord-257197-i9bucuma	266	24	 	 	_SP
cord-257197-i9bucuma	267	1	Analyzing	analyze	VBG
cord-257197-i9bucuma	267	2	nanomaterial	nanomaterial	JJ
cord-257197-i9bucuma	267	3	bioconjugates	bioconjugates	NNPS
cord-257197-i9bucuma	267	4	:	:	:
cord-257197-i9bucuma	267	5	a	a	DT
cord-257197-i9bucuma	267	6	review	review	NN
cord-257197-i9bucuma	267	7	of	of	IN
cord-257197-i9bucuma	267	8	current	current	JJ
cord-257197-i9bucuma	267	9	and	and	CC
cord-257197-i9bucuma	267	10	emerging	emerge	VBG
cord-257197-i9bucuma	267	11	purification	purification	NN
cord-257197-i9bucuma	267	12	and	and	CC
cord-257197-i9bucuma	267	13	characterization	characterization	NN
cord-257197-i9bucuma	267	14	techniques	technique	NNS
cord-257197-i9bucuma	267	15	Functionalizing	functionalize	VBG
cord-257197-i9bucuma	267	16	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	267	17	with	with	IN
cord-257197-i9bucuma	267	18	biological	biological	JJ
cord-257197-i9bucuma	267	19	molecules	molecule	NNS
cord-257197-i9bucuma	267	20	:	:	:
cord-257197-i9bucuma	267	21	developing	develop	VBG
cord-257197-i9bucuma	267	22	chemistries	chemistry	NNS
cord-257197-i9bucuma	267	23	that	that	WDT
cord-257197-i9bucuma	267	24	facilitate	facilitate	VBP
cord-257197-i9bucuma	267	25	nanotechnology	nanotechnology	NN
cord-257197-i9bucuma	267	26	Doxorubicin	Doxorubicin	NNP
cord-257197-i9bucuma	267	27	/	/	SYM
cord-257197-i9bucuma	267	28	gold	gold	NN
cord-257197-i9bucuma	267	29	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	267	30	coated	coat	VBN
cord-257197-i9bucuma	267	31	with	with	IN
cord-257197-i9bucuma	267	32	liposomes	liposome	NNS
cord-257197-i9bucuma	267	33	for	for	IN
cord-257197-i9bucuma	267	34	chemo	chemo	NN
cord-257197-i9bucuma	267	35	-	-	HYPH
cord-257197-i9bucuma	267	36	photothermal	photothermal	JJ
cord-257197-i9bucuma	267	37	synergetic	synergetic	JJ
cord-257197-i9bucuma	267	38	antitumor	antitumor	NN
cord-257197-i9bucuma	267	39	therapy	therapy	NN
cord-257197-i9bucuma	267	40	Cell	cell	NN
cord-257197-i9bucuma	267	41	-	-	HYPH
cord-257197-i9bucuma	267	42	Membrane	Membrane	NNP
cord-257197-i9bucuma	268	1	-Mimicking	-mimicke	VBG
cord-257197-i9bucuma	268	2	Lipid	Lipid	NNP
cord-257197-i9bucuma	268	3	-	-	HYPH
cord-257197-i9bucuma	268	4	Coated	coat	VBN
cord-257197-i9bucuma	268	5	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	268	6	Confer	confer	VBP
cord-257197-i9bucuma	268	7	Raman	Raman	NNP
cord-257197-i9bucuma	268	8	Enhancement	Enhancement	NNP
cord-257197-i9bucuma	268	9	to	to	IN
cord-257197-i9bucuma	268	10	Membrane	membrane	NN
cord-257197-i9bucuma	268	11	Proteins	protein	NNS
cord-257197-i9bucuma	268	12	and	and	CC
cord-257197-i9bucuma	268	13	Reveal	reveal	VB
cord-257197-i9bucuma	268	14	Membrane	membrane	NN
cord-257197-i9bucuma	268	15	-	-	HYPH
cord-257197-i9bucuma	268	16	Attached	attach	VBN
cord-257197-i9bucuma	268	17	Amyloid	amyloid	NN
cord-257197-i9bucuma	268	18	-	-	HYPH
cord-257197-i9bucuma	268	19	beta	beta	NN
cord-257197-i9bucuma	268	20	Conformation	Conformation	NNP
cord-257197-i9bucuma	268	21	Cationic	Cationic	NNP
cord-257197-i9bucuma	268	22	Lipid	Lipid	NNP
cord-257197-i9bucuma	268	23	-	-	HYPH
cord-257197-i9bucuma	268	24	Coated	Coated	NNP
cord-257197-i9bucuma	268	25	Gold	Gold	NNP
cord-257197-i9bucuma	268	26	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	268	27	as	as	IN
cord-257197-i9bucuma	268	28	Efficient	efficient	JJ
cord-257197-i9bucuma	268	29	and	and	CC
cord-257197-i9bucuma	268	30	Non	Non	NNP
cord-257197-i9bucuma	268	31	-	-	NNP
cord-257197-i9bucuma	268	32	Cytotoxic	Cytotoxic	NNP
cord-257197-i9bucuma	269	1	Intracellular	Intracellular	NNP
cord-257197-i9bucuma	269	2	siRNA	siRNA	NNP
cord-257197-i9bucuma	269	3	Delivery	Delivery	NNP
cord-257197-i9bucuma	269	4	Vehicles	vehicle	NNS
cord-257197-i9bucuma	270	1	Polymeric	Polymeric	NNP
cord-257197-i9bucuma	270	2	Liposomes	Liposomes	NNP
cord-257197-i9bucuma	270	3	-	-	HYPH
cord-257197-i9bucuma	270	4	Coated	Coated	NNP
cord-257197-i9bucuma	270	5	Superparamagnetic	Superparamagnetic	NNP
cord-257197-i9bucuma	270	6	Iron	Iron	NNP
cord-257197-i9bucuma	270	7	Oxide	Oxide	NNP
cord-257197-i9bucuma	270	8	Nanoparticles	Nanoparticles	NNP
cord-257197-i9bucuma	270	9	as	as	IN
cord-257197-i9bucuma	270	10	Contrast	Contrast	NNP
cord-257197-i9bucuma	270	11	Agent	Agent	NNP
cord-257197-i9bucuma	270	12	for	for	IN
cord-257197-i9bucuma	270	13	Targeted	Targeted	NNP
cord-257197-i9bucuma	270	14	Magnetic	Magnetic	NNP
cord-257197-i9bucuma	270	15	Resonance	Resonance	NNP
cord-257197-i9bucuma	270	16	Imaging	Imaging	NNP
cord-257197-i9bucuma	270	17	of	of	IN
cord-257197-i9bucuma	270	18	Cancer	Cancer	NNP
cord-257197-i9bucuma	270	19	Cells	cell	NNS
cord-257197-i9bucuma	270	20	Biodegradable	biodegradable	JJ
cord-257197-i9bucuma	270	21	Drug	Drug	NNP
cord-257197-i9bucuma	270	22	-	-	HYPH
cord-257197-i9bucuma	270	23	Delivery	Delivery	NNP
cord-257197-i9bucuma	270	24	Peptide	Peptide	NNP
cord-257197-i9bucuma	270	25	Nanocapsules	Nanocapsules	NNP
cord-257197-i9bucuma	270	26	Self	Self	NNP
cord-257197-i9bucuma	270	27	-	-	HYPH
cord-257197-i9bucuma	270	28	Assembly	Assembly	NNP
cord-257197-i9bucuma	270	29	Mechanism	Mechanism	NNP
cord-257197-i9bucuma	270	30	of	of	IN
cord-257197-i9bucuma	270	31	a	a	DT
cord-257197-i9bucuma	270	32	Peptide	Peptide	NNP
cord-257197-i9bucuma	270	33	-	-	HYPH
cord-257197-i9bucuma	270	34	Based	Based	NNP
cord-257197-i9bucuma	270	35	Drug	Drug	NNP
cord-257197-i9bucuma	270	36	Delivery	Delivery	NNP
cord-257197-i9bucuma	270	37	Vehicle	Vehicle	NNP
cord-257197-i9bucuma	270	38	Stimuli	Stimuli	NNPS
cord-257197-i9bucuma	270	39	-	-	HYPH
cord-257197-i9bucuma	270	40	responsive	responsive	JJ
cord-257197-i9bucuma	270	41	polypeptide	polypeptide	NN
cord-257197-i9bucuma	270	42	vesicles	vesicle	NNS
cord-257197-i9bucuma	270	43	by	by	IN
cord-257197-i9bucuma	270	44	conformation	conformation	NN
cord-257197-i9bucuma	270	45	-	-	HYPH
cord-257197-i9bucuma	270	46	specific	specific	JJ
cord-257197-i9bucuma	270	47	assembly	assembly	NN
cord-257197-i9bucuma	270	48	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	270	49	of	of	IN
cord-257197-i9bucuma	270	50	Hollow	Hollow	NNP
cord-257197-i9bucuma	270	51	Polymer	Polymer	NNP
cord-257197-i9bucuma	270	52	Nanocapsules	Nanocapsules	NNP
cord-257197-i9bucuma	270	53	Exploiting	exploit	VBG
cord-257197-i9bucuma	270	54	Gold	Gold	NNP
cord-257197-i9bucuma	270	55	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	270	56	as	as	IN
cord-257197-i9bucuma	270	57	Sacrificial	sacrificial	JJ
cord-257197-i9bucuma	270	58	Templates	Templates	NNPS
cord-257197-i9bucuma	270	59	Differentially	differentially	RB
cord-257197-i9bucuma	270	60	Charged	Charged	NNP
cord-257197-i9bucuma	270	61	Hollow	Hollow	NNP
cord-257197-i9bucuma	270	62	Core	Core	NNP
cord-257197-i9bucuma	270	63	/	/	SYM
cord-257197-i9bucuma	270	64	Shell	Shell	NNP
cord-257197-i9bucuma	270	65	Lipid	Lipid	NNP
cord-257197-i9bucuma	270	66	-	-	HYPH
cord-257197-i9bucuma	270	67	Polymer	Polymer	NNP
cord-257197-i9bucuma	270	68	-	-	HYPH
cord-257197-i9bucuma	270	69	Lipid	Lipid	NNP
cord-257197-i9bucuma	270	70	Hybrid	Hybrid	NNP
cord-257197-i9bucuma	270	71	Nanoparticles	Nanoparticles	NNP
cord-257197-i9bucuma	270	72	for	for	IN
cord-257197-i9bucuma	270	73	Small	Small	NNP
cord-257197-i9bucuma	270	74	Interfering	Interfering	NNP
cord-257197-i9bucuma	270	75	RNA	RNA	NNP
cord-257197-i9bucuma	270	76	Delivery	Delivery	NNP
cord-257197-i9bucuma	270	77	Bioreducible	Bioreducible	NNP
cord-257197-i9bucuma	270	78	Cationic	Cationic	NNP
cord-257197-i9bucuma	270	79	Polymer	Polymer	NNP
cord-257197-i9bucuma	270	80	-	-	HYPH
cord-257197-i9bucuma	270	81	Based	base	VBN
cord-257197-i9bucuma	270	82	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	270	83	for	for	IN
cord-257197-i9bucuma	270	84	Efficient	efficient	JJ
cord-257197-i9bucuma	270	85	and	and	CC
cord-257197-i9bucuma	270	86	Environmentally	environmentally	RB
cord-257197-i9bucuma	271	1	Triggered	Triggered	NNP
cord-257197-i9bucuma	271	2	Cytoplasmic	Cytoplasmic	NNP
cord-257197-i9bucuma	271	3	siRNA	siRNA	NNP
cord-257197-i9bucuma	271	4	Delivery	Delivery	NNP
cord-257197-i9bucuma	271	5	to	to	IN
cord-257197-i9bucuma	271	6	Primary	Primary	NNP
cord-257197-i9bucuma	271	7	Human	Human	NNP
cord-257197-i9bucuma	271	8	Brain	Brain	NNP
cord-257197-i9bucuma	271	9	Cancer	Cancer	NNP
cord-257197-i9bucuma	271	10	Cells	cell	NNS
cord-257197-i9bucuma	272	1	Pretreated	Pretreated	NNP
cord-257197-i9bucuma	272	2	Macrophage	Macrophage	NNP
cord-257197-i9bucuma	272	3	-	-	HYPH
cord-257197-i9bucuma	272	4	Membrane	Membrane	NNP
cord-257197-i9bucuma	272	5	-	-	HYPH
cord-257197-i9bucuma	272	6	Coated	Coated	NNP
cord-257197-i9bucuma	272	7	Gold	Gold	NNP
cord-257197-i9bucuma	272	8	Nanocages	Nanocages	NNP
cord-257197-i9bucuma	272	9	for	for	IN
cord-257197-i9bucuma	272	10	Precise	Precise	NNP
cord-257197-i9bucuma	272	11	Drug	Drug	NNP
cord-257197-i9bucuma	272	12	Delivery	Delivery	NNP
cord-257197-i9bucuma	272	13	for	for	IN
cord-257197-i9bucuma	272	14	Treatment	treatment	NN
cord-257197-i9bucuma	272	15	of	of	IN
cord-257197-i9bucuma	272	16	Bacterial	bacterial	JJ
cord-257197-i9bucuma	272	17	Infections	Infections	NNPS
cord-257197-i9bucuma	272	18	Designed	design	VBN
cord-257197-i9bucuma	272	19	formation	formation	NN
cord-257197-i9bucuma	272	20	through	through	IN
cord-257197-i9bucuma	272	21	a	a	DT
cord-257197-i9bucuma	272	22	metal	metal	JJ
cord-257197-i9bucuma	272	23	organic	organic	JJ
cord-257197-i9bucuma	272	24	framework	framework	NN
cord-257197-i9bucuma	272	25	route	route	NN
cord-257197-i9bucuma	272	26	of	of	IN
cord-257197-i9bucuma	272	27	ZnO	ZnO	NNP
cord-257197-i9bucuma	272	28	/	/	SYM
cord-257197-i9bucuma	272	29	ZnCo2O4	ZnCo2O4	NNP
cord-257197-i9bucuma	272	30	hollow	hollow	JJ
cord-257197-i9bucuma	272	31	core	core	NN
cord-257197-i9bucuma	272	32	-	-	HYPH
cord-257197-i9bucuma	272	33	shell	shell	JJ
cord-257197-i9bucuma	272	34	nanocages	nanocage	NNS
cord-257197-i9bucuma	272	35	with	with	IN
cord-257197-i9bucuma	272	36	enhanced	enhance	VBN
cord-257197-i9bucuma	272	37	gas	gas	NN
cord-257197-i9bucuma	272	38	sensing	sensing	NN
cord-257197-i9bucuma	272	39	properties	property	NNS
cord-257197-i9bucuma	273	1	Mesoporous	Mesoporous	NNP
cord-257197-i9bucuma	273	2	Hollow	Hollow	NNP
cord-257197-i9bucuma	273	3	Cu	Cu	NNP
cord-257197-i9bucuma	273	4	-	-	HYPH
cord-257197-i9bucuma	273	5	Ni	Ni	NNP
cord-257197-i9bucuma	273	6	Alloy	Alloy	NNP
cord-257197-i9bucuma	273	7	Nanocage	Nanocage	NNP
cord-257197-i9bucuma	273	8	from	from	IN
cord-257197-i9bucuma	273	9	Core	Core	NNP
cord-257197-i9bucuma	273	10	-	-	HYPH
cord-257197-i9bucuma	273	11	Shell	Shell	NNP
cord-257197-i9bucuma	273	12	Cu@Ni	Cu@Ni	NNP
cord-257197-i9bucuma	273	13	Nanocube	Nanocube	NNP
cord-257197-i9bucuma	273	14	for	for	IN
cord-257197-i9bucuma	274	1	Efficient	efficient	JJ
cord-257197-i9bucuma	274	2	Hydrogen	Hydrogen	NNP
cord-257197-i9bucuma	274	3	Evolution	Evolution	NNP
cord-257197-i9bucuma	274	4	Reaction	Reaction	NNP
cord-257197-i9bucuma	274	5	Nano	Nano	NNP
cord-257197-i9bucuma	274	6	based	base	VBN
cord-257197-i9bucuma	274	7	drug	drug	NN
cord-257197-i9bucuma	274	8	delivery	delivery	NN
cord-257197-i9bucuma	274	9	systems	system	NNS
cord-257197-i9bucuma	274	10	:	:	:
cord-257197-i9bucuma	274	11	recent	recent	JJ
cord-257197-i9bucuma	274	12	developments	development	NNS
cord-257197-i9bucuma	274	13	and	and	CC
cord-257197-i9bucuma	274	14	future	future	JJ
cord-257197-i9bucuma	274	15	prospects	prospect	NNS
cord-257197-i9bucuma	275	1	Transferrin	Transferrin	NNP
cord-257197-i9bucuma	275	2	receptor	receptor	NN
cord-257197-i9bucuma	275	3	-	-	HYPH
cord-257197-i9bucuma	275	4	targeted	target	VBN
cord-257197-i9bucuma	275	5	theranostic	theranostic	JJ
cord-257197-i9bucuma	275	6	gold	gold	NN
cord-257197-i9bucuma	275	7	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	275	8	for	for	IN
cord-257197-i9bucuma	275	9	photosensitizer	photosensitizer	NNP
cord-257197-i9bucuma	275	10	delivery	delivery	NN
cord-257197-i9bucuma	275	11	in	in	IN
cord-257197-i9bucuma	275	12	brain	brain	NN
cord-257197-i9bucuma	275	13	tumors	tumor	NNS
cord-257197-i9bucuma	276	1	Enhanced	enhanced	JJ
cord-257197-i9bucuma	276	2	accumulation	accumulation	NN
cord-257197-i9bucuma	276	3	of	of	IN
cord-257197-i9bucuma	276	4	theranostic	theranostic	JJ
cord-257197-i9bucuma	276	5	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	276	6	in	in	IN
cord-257197-i9bucuma	276	7	brain	brain	NN
cord-257197-i9bucuma	276	8	tumor	tumor	NN
cord-257197-i9bucuma	276	9	by	by	IN
cord-257197-i9bucuma	276	10	external	external	JJ
cord-257197-i9bucuma	276	11	magnetic	magnetic	JJ
cord-257197-i9bucuma	276	12	field	field	NN
cord-257197-i9bucuma	276	13	mediated	mediate	VBN
cord-257197-i9bucuma	276	14	in	in	IN
cord-257197-i9bucuma	276	15	situ	situ	NN
cord-257197-i9bucuma	276	16	clustering	clustering	NN
cord-257197-i9bucuma	276	17	of	of	IN
cord-257197-i9bucuma	276	18	magnetic	magnetic	JJ
cord-257197-i9bucuma	276	19	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	276	20	Erlotinib	Erlotinib	NNP
cord-257197-i9bucuma	276	21	-	-	HYPH
cord-257197-i9bucuma	276	22	Conjugated	Conjugated	NNP
cord-257197-i9bucuma	276	23	Iron	Iron	NNP
cord-257197-i9bucuma	276	24	Oxide	Oxide	NNP
cord-257197-i9bucuma	276	25	Nanoparticles	Nanoparticles	NNP
cord-257197-i9bucuma	276	26	as	as	IN
cord-257197-i9bucuma	276	27	a	a	DT
cord-257197-i9bucuma	276	28	Smart	Smart	NNP
cord-257197-i9bucuma	276	29	Cancer	Cancer	NNP
cord-257197-i9bucuma	276	30	-	-	HYPH
cord-257197-i9bucuma	276	31	Targeted	Targeted	NNP
cord-257197-i9bucuma	276	32	Theranostic	Theranostic	NNP
cord-257197-i9bucuma	276	33	Probe	Probe	NNP
cord-257197-i9bucuma	276	34	for	for	IN
cord-257197-i9bucuma	276	35	MRI	MRI	NNP
cord-257197-i9bucuma	276	36	MRI	MRI	NNP
cord-257197-i9bucuma	276	37	Guided	Guided	NNP
cord-257197-i9bucuma	276	38	Magnetochemotherapy	Magnetochemotherapy	NNP
cord-257197-i9bucuma	276	39	with	with	IN
cord-257197-i9bucuma	276	40	High	high	JJ
cord-257197-i9bucuma	276	41	-	-	HYPH
cord-257197-i9bucuma	276	42	Magnetic	magnetic	JJ
cord-257197-i9bucuma	276	43	-	-	HYPH
cord-257197-i9bucuma	276	44	Moment	Moment	NNP
cord-257197-i9bucuma	276	45	Iron	Iron	NNP
cord-257197-i9bucuma	276	46	Oxide	oxide	NN
cord-257197-i9bucuma	276	47	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	276	48	for	for	IN
cord-257197-i9bucuma	276	49	Cancer	Cancer	NNP
cord-257197-i9bucuma	276	50	Theranostics	Theranostics	NNP
cord-257197-i9bucuma	276	51	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	276	52	-	-	HYPH
cord-257197-i9bucuma	276	53	Based	base	VBN
cord-257197-i9bucuma	276	54	Medicines	medicine	NNS
cord-257197-i9bucuma	276	55	:	:	:
cord-257197-i9bucuma	277	1	A	a	DT
cord-257197-i9bucuma	277	2	Review	Review	NNP
cord-257197-i9bucuma	277	3	of	of	IN
cord-257197-i9bucuma	277	4	FDA	FDA	NNP
cord-257197-i9bucuma	277	5	-	-	HYPH
cord-257197-i9bucuma	277	6	Approved	Approved	NNP
cord-257197-i9bucuma	277	7	Materials	Materials	NNP
cord-257197-i9bucuma	277	8	and	and	CC
cord-257197-i9bucuma	277	9	Clinical	Clinical	NNP
cord-257197-i9bucuma	277	10	Trials	trial	NNS
cord-257197-i9bucuma	277	11	to	to	IN
cord-257197-i9bucuma	277	12	Date	Date	NNP
cord-257197-i9bucuma	277	13	Nano	Nano	NNP
cord-257197-i9bucuma	277	14	Research	Research	NNP
cord-257197-i9bucuma	277	15	for	for	IN
cord-257197-i9bucuma	277	16	COVID-19	COVID-19	NNP
cord-257197-i9bucuma	278	1	Rapid	Rapid	NNP
cord-257197-i9bucuma	278	2	COVID-19	COVID-19	NNP
cord-257197-i9bucuma	278	3	test	test	NN
cord-257197-i9bucuma	278	4	based	base	VBN
cord-257197-i9bucuma	278	5	on	on	IN
cord-257197-i9bucuma	278	6	new	new	JJ
cord-257197-i9bucuma	278	7	biolabeling	biolabele	VBG
cord-257197-i9bucuma	278	8	technology	technology	NN
cord-257197-i9bucuma	278	9	called	call	VBN
cord-257197-i9bucuma	278	10	plasmonic	plasmonic	NN
cord-257197-i9bucuma	278	11	-	-	HYPH
cord-257197-i9bucuma	278	12	fluor	fluor	NNP
cord-257197-i9bucuma	278	13	Ultrabright	Ultrabright	NNP
cord-257197-i9bucuma	278	14	fluorescent	fluorescent	NN
cord-257197-i9bucuma	278	15	nanoscale	nanoscale	NN
cord-257197-i9bucuma	278	16	labels	label	NNS
cord-257197-i9bucuma	278	17	for	for	IN
cord-257197-i9bucuma	278	18	the	the	DT
cord-257197-i9bucuma	278	19	femtomolar	femtomolar	JJ
cord-257197-i9bucuma	278	20	detection	detection	NN
cord-257197-i9bucuma	278	21	of	of	IN
cord-257197-i9bucuma	278	22	analytes	analyte	NNS
cord-257197-i9bucuma	278	23	with	with	IN
cord-257197-i9bucuma	278	24	standard	standard	JJ
cord-257197-i9bucuma	278	25	bioassays	bioassay	NNS
cord-257197-i9bucuma	278	26	Identifier	Identifier	NNP
cord-257197-i9bucuma	278	27	NCT04283461	NCT04283461	NNP
cord-257197-i9bucuma	278	28	,	,	,
cord-257197-i9bucuma	278	29	Safety	Safety	NNP
cord-257197-i9bucuma	278	30	and	and	CC
cord-257197-i9bucuma	278	31	Immunogenicity	Immunogenicity	NNP
cord-257197-i9bucuma	278	32	Study	Study	NNP
cord-257197-i9bucuma	278	33	of	of	IN
cord-257197-i9bucuma	278	34	2019-nCoV	2019-ncov	CD
cord-257197-i9bucuma	278	35	Vaccine	vaccine	NN
cord-257197-i9bucuma	278	36	(	(	-LRB-
cord-257197-i9bucuma	278	37	mRNA-1273	mrna-1273	XX
cord-257197-i9bucuma	278	38	)	)	-RRB-
cord-257197-i9bucuma	278	39	for	for	IN
cord-257197-i9bucuma	278	40	Prophylaxis	Prophylaxis	NNP
cord-257197-i9bucuma	278	41	of	of	IN
cord-257197-i9bucuma	278	42	SARS	SARS	NNP
cord-257197-i9bucuma	278	43	-	-	HYPH
cord-257197-i9bucuma	278	44	CoV-2	CoV-2	NNP
cord-257197-i9bucuma	278	45	Infection	Infection	NNP
cord-257197-i9bucuma	278	46	Analysis	Analysis	NNP
cord-257197-i9bucuma	278	47	of	of	IN
cord-257197-i9bucuma	278	48	complexes	complex	NNS
cord-257197-i9bucuma	278	49	formed	form	VBN
cord-257197-i9bucuma	278	50	by	by	IN
cord-257197-i9bucuma	278	51	small	small	JJ
cord-257197-i9bucuma	278	52	gold	gold	NN
cord-257197-i9bucuma	278	53	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	278	54	in	in	IN
cord-257197-i9bucuma	278	55	low	low	JJ
cord-257197-i9bucuma	278	56	concentration	concentration	NN
cord-257197-i9bucuma	278	57	in	in	IN
cord-257197-i9bucuma	278	58	cell	cell	NN
cord-257197-i9bucuma	278	59	culture	culture	NN
cord-257197-i9bucuma	278	60	media	medium	NNS
cord-257197-i9bucuma	278	61	Tracing	Tracing	NNP
cord-257197-i9bucuma	278	62	Size	Size	NNP
cord-257197-i9bucuma	278	63	and	and	CC
cord-257197-i9bucuma	278	64	Surface	Surface	NNP
cord-257197-i9bucuma	278	65	Chemistry	Chemistry	NNP
cord-257197-i9bucuma	278	66	-	-	HYPH
cord-257197-i9bucuma	278	67	Dependent	Dependent	NNP
cord-257197-i9bucuma	278	68	Endosomal	Endosomal	NNP
cord-257197-i9bucuma	278	69	Uptake	Uptake	NNP
cord-257197-i9bucuma	278	70	of	of	IN
cord-257197-i9bucuma	278	71	Gold	Gold	NNP
cord-257197-i9bucuma	278	72	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	278	73	Using	use	VBG
cord-257197-i9bucuma	278	74	Surface	surface	NN
cord-257197-i9bucuma	278	75	-	-	HYPH
cord-257197-i9bucuma	278	76	Enhanced	Enhanced	NNP
cord-257197-i9bucuma	278	77	Raman	Raman	NNP
cord-257197-i9bucuma	278	78	Scattering	Scattering	NNP
cord-257197-i9bucuma	278	79	Quantitative	quantitative	JJ
cord-257197-i9bucuma	278	80	visualization	visualization	NN
cord-257197-i9bucuma	278	81	of	of	IN
cord-257197-i9bucuma	278	82	colloidal	colloidal	NN
cord-257197-i9bucuma	278	83	and	and	CC
cord-257197-i9bucuma	278	84	intracellular	intracellular	JJ
cord-257197-i9bucuma	278	85	gold	gold	NN
cord-257197-i9bucuma	278	86	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	278	87	by	by	IN
cord-257197-i9bucuma	278	88	confocal	confocal	JJ
cord-257197-i9bucuma	278	89	microscopy	microscopy	NNS
cord-257197-i9bucuma	279	1	Cellular	Cellular	NNP
cord-257197-i9bucuma	279	2	Uptake	Uptake	NNP
cord-257197-i9bucuma	279	3	and	and	CC
cord-257197-i9bucuma	279	4	Nanoscale	Nanoscale	NNP
cord-257197-i9bucuma	279	5	Localization	Localization	NNP
cord-257197-i9bucuma	279	6	of	of	IN
cord-257197-i9bucuma	279	7	Gold	Gold	NNP
cord-257197-i9bucuma	279	8	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	279	9	in	in	IN
cord-257197-i9bucuma	279	10	Cancer	cancer	NN
cord-257197-i9bucuma	279	11	Using	use	VBG
cord-257197-i9bucuma	279	12	Label	Label	NNP
cord-257197-i9bucuma	279	13	-	-	HYPH
cord-257197-i9bucuma	279	14	Free	Free	NNP
cord-257197-i9bucuma	279	15	Confocal	Confocal	NNP
cord-257197-i9bucuma	279	16	Raman	Raman	NNP
cord-257197-i9bucuma	279	17	Microscopy	Microscopy	NNP
cord-257197-i9bucuma	279	18	Exceedingly	exceedingly	RB
cord-257197-i9bucuma	279	19	small	small	JJ
cord-257197-i9bucuma	279	20	iron	iron	NN
cord-257197-i9bucuma	279	21	oxide	oxide	NN
cord-257197-i9bucuma	279	22	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	279	23	as	as	IN
cord-257197-i9bucuma	279	24	positive	positive	JJ
cord-257197-i9bucuma	279	25	MRI	MRI	NNP
cord-257197-i9bucuma	279	26	contrast	contrast	NN
cord-257197-i9bucuma	279	27	agents	agent	NNS
cord-257197-i9bucuma	279	28	Differentiating	differentiate	VBG
cord-257197-i9bucuma	279	29	Between	between	IN
cord-257197-i9bucuma	279	30	Cancer	Cancer	NNP
cord-257197-i9bucuma	279	31	and	and	CC
cord-257197-i9bucuma	279	32	Inflammation	inflammation	NN
cord-257197-i9bucuma	279	33	:	:	:
cord-257197-i9bucuma	279	34	A	a	DT
cord-257197-i9bucuma	279	35	Metabolic	Metabolic	NNP
cord-257197-i9bucuma	279	36	-	-	HYPH
cord-257197-i9bucuma	279	37	Based	base	VBN
cord-257197-i9bucuma	279	38	Method	Method	NNP
cord-257197-i9bucuma	279	39	for	for	IN
cord-257197-i9bucuma	279	40	Functional	Functional	NNP
cord-257197-i9bucuma	279	41	Computed	Computed	NNP
cord-257197-i9bucuma	279	42	Tomography	Tomography	NNP
cord-257197-i9bucuma	279	43	Imaging	Imaging	NNP
cord-257197-i9bucuma	279	44	Potential	potential	JJ
cord-257197-i9bucuma	279	45	use	use	NN
cord-257197-i9bucuma	279	46	of	of	IN
cord-257197-i9bucuma	279	47	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	279	48	iron	iron	NN
cord-257197-i9bucuma	279	49	oxide	oxide	NN
cord-257197-i9bucuma	279	50	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	279	51	for	for	IN
cord-257197-i9bucuma	279	52	in	in	FW
cord-257197-i9bucuma	279	53	vitro	vitro	FW
cord-257197-i9bucuma	279	54	and	and	CC
cord-257197-i9bucuma	279	55	in	in	IN
cord-257197-i9bucuma	279	56	vivo	vivo	FW
cord-257197-i9bucuma	279	57	bioimaging	bioimaging	NNP
cord-257197-i9bucuma	279	58	of	of	IN
cord-257197-i9bucuma	279	59	human	human	JJ
cord-257197-i9bucuma	279	60	myoblasts	myoblast	NNS
cord-257197-i9bucuma	279	61	GO	GO	NNP
cord-257197-i9bucuma	279	62	-	-	HYPH
cord-257197-i9bucuma	279	63	Functionalized	Functionalized	NNP
cord-257197-i9bucuma	279	64	Large	Large	NNP
cord-257197-i9bucuma	279	65	Magnetic	Magnetic	NNP
cord-257197-i9bucuma	279	66	Iron	Iron	NNP
cord-257197-i9bucuma	279	67	Oxide	oxide	NN
cord-257197-i9bucuma	279	68	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	279	69	with	with	IN
cord-257197-i9bucuma	279	70	Enhanced	Enhanced	NNP
cord-257197-i9bucuma	279	71	Colloidal	Colloidal	NNP
cord-257197-i9bucuma	279	72	Stability	Stability	NNP
cord-257197-i9bucuma	279	73	and	and	CC
cord-257197-i9bucuma	279	74	Hyperthermia	Hyperthermia	NNP
cord-257197-i9bucuma	279	75	Performance	Performance	NNP
cord-257197-i9bucuma	279	76	Water	Water	NNP
cord-257197-i9bucuma	279	77	-	-	HYPH
cord-257197-i9bucuma	279	78	Dispersible	Dispersible	NNP
cord-257197-i9bucuma	279	79	Sugar	Sugar	NNP
cord-257197-i9bucuma	279	80	-	-	HYPH
cord-257197-i9bucuma	279	81	Coated	Coated	NNP
cord-257197-i9bucuma	279	82	Iron	Iron	NNP
cord-257197-i9bucuma	279	83	Oxide	Oxide	NNP
cord-257197-i9bucuma	279	84	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	279	85	.	.	.
cord-257197-i9bucuma	280	1	An	an	DT
cord-257197-i9bucuma	280	2	Evaluation	evaluation	NN
cord-257197-i9bucuma	280	3	of	of	IN
cord-257197-i9bucuma	280	4	their	-PRON-	PRP$
cord-257197-i9bucuma	280	5	Relaxometric	Relaxometric	NNP
cord-257197-i9bucuma	280	6	and	and	CC
cord-257197-i9bucuma	280	7	Magnetic	magnetic	JJ
cord-257197-i9bucuma	280	8	Hyperthermia	Hyperthermia	NNP
cord-257197-i9bucuma	280	9	Properties	Properties	NNPS
cord-257197-i9bucuma	280	10	Have	have	VBP
cord-257197-i9bucuma	280	11	Nanoscience	Nanoscience	NNP
cord-257197-i9bucuma	280	12	and	and	CC
cord-257197-i9bucuma	280	13	Nanotechnology	Nanotechnology	NNP
cord-257197-i9bucuma	280	14	Delivered	deliver	VBN
cord-257197-i9bucuma	280	15	?	?	.
cord-257197-i9bucuma	281	1	Progress	progress	VB
cord-257197-i9bucuma	281	2	towards	towards	IN
cord-257197-i9bucuma	281	3	standardized	standardized	JJ
cord-257197-i9bucuma	281	4	and	and	CC
cord-257197-i9bucuma	281	5	validated	validate	VBN
cord-257197-i9bucuma	281	6	characterizations	characterization	NNS
cord-257197-i9bucuma	281	7	for	for	IN
cord-257197-i9bucuma	281	8	measuring	measure	VBG
cord-257197-i9bucuma	281	9	physicochemical	physicochemical	JJ
cord-257197-i9bucuma	281	10	properties	property	NNS
cord-257197-i9bucuma	281	11	of	of	IN
cord-257197-i9bucuma	281	12	manufactured	manufacture	VBN
cord-257197-i9bucuma	281	13	nanomaterials	nanomaterial	NNS
cord-257197-i9bucuma	281	14	relevant	relevant	JJ
cord-257197-i9bucuma	281	15	to	to	IN
cord-257197-i9bucuma	281	16	nano	nano	NNP
cord-257197-i9bucuma	281	17	health	health	NN
cord-257197-i9bucuma	281	18	and	and	CC
cord-257197-i9bucuma	281	19	safety	safety	NN
cord-257197-i9bucuma	281	20	risks	risk	VBZ
cord-257197-i9bucuma	281	21	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	281	22	,	,	,
cord-257197-i9bucuma	281	23	characterization	characterization	NN
cord-257197-i9bucuma	281	24	,	,	,
cord-257197-i9bucuma	281	25	applications	application	NNS
cord-257197-i9bucuma	281	26	,	,	,
cord-257197-i9bucuma	281	27	and	and	CC
cord-257197-i9bucuma	281	28	challenges	challenge	NNS
cord-257197-i9bucuma	281	29	of	of	IN
cord-257197-i9bucuma	281	30	iron	iron	NN
cord-257197-i9bucuma	281	31	oxide	oxide	NN
cord-257197-i9bucuma	281	32	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	281	33	Size	size	NN
cord-257197-i9bucuma	281	34	-	-	HYPH
cord-257197-i9bucuma	281	35	Controlled	control	VBN
cord-257197-i9bucuma	281	36	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	281	37	of	of	IN
cord-257197-i9bucuma	281	38	Sub-10-nanometer	Sub-10-nanometer	NNP
cord-257197-i9bucuma	281	39	Citrate	Citrate	NNP
cord-257197-i9bucuma	281	40	-	-	HYPH
cord-257197-i9bucuma	281	41	Stabilized	Stabilized	NNP
cord-257197-i9bucuma	281	42	Gold	Gold	NNP
cord-257197-i9bucuma	281	43	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	281	44	and	and	CC
cord-257197-i9bucuma	281	45	Related	Related	NNP
cord-257197-i9bucuma	281	46	Optical	Optical	NNP
cord-257197-i9bucuma	281	47	Properties	Properties	NNPS
cord-257197-i9bucuma	281	48	Digestive	Digestive	NNP
cord-257197-i9bucuma	281	49	ripening	ripen	VBG
cord-257197-i9bucuma	281	50	,	,	,
cord-257197-i9bucuma	281	51	nanophase	nanophase	JJ
cord-257197-i9bucuma	281	52	segregation	segregation	NN
cord-257197-i9bucuma	281	53	and	and	CC
cord-257197-i9bucuma	281	54	superlattice	superlattice	NN
cord-257197-i9bucuma	281	55	formation	formation	NN
cord-257197-i9bucuma	281	56	in	in	IN
cord-257197-i9bucuma	281	57	gold	gold	JJ
cord-257197-i9bucuma	281	58	nanocrystal	nanocrystal	JJ
cord-257197-i9bucuma	281	59	colloids	colloid	NNS
cord-257197-i9bucuma	281	60	Optimal	Optimal	NNP
cord-257197-i9bucuma	281	61	Design	Design	NNP
cord-257197-i9bucuma	281	62	and	and	CC
cord-257197-i9bucuma	281	63	Characterization	characterization	NN
cord-257197-i9bucuma	281	64	of	of	IN
cord-257197-i9bucuma	281	65	Superparamagnetic	Superparamagnetic	NNP
cord-257197-i9bucuma	281	66	Iron	Iron	NNP
cord-257197-i9bucuma	281	67	Oxide	Oxide	NNP
cord-257197-i9bucuma	281	68	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	281	69	Coated	coat	VBN
cord-257197-i9bucuma	281	70	with	with	IN
cord-257197-i9bucuma	281	71	Polyvinyl	polyvinyl	NN
cord-257197-i9bucuma	281	72	Alcohol	Alcohol	NNP
cord-257197-i9bucuma	281	73	for	for	IN
cord-257197-i9bucuma	281	74	Targeted	target	VBN
cord-257197-i9bucuma	281	75	Delivery	Delivery	NNP
cord-257197-i9bucuma	281	76	and	and	CC
cord-257197-i9bucuma	281	77	Imaging	Imaging	NNP
cord-257197-i9bucuma	281	78	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	281	79	and	and	CC
cord-257197-i9bucuma	281	80	characterization	characterization	NN
cord-257197-i9bucuma	281	81	of	of	IN
cord-257197-i9bucuma	281	82	nanometer	nanometer	NN
cord-257197-i9bucuma	281	83	-	-	HYPH
cord-257197-i9bucuma	281	84	size	size	NN
cord-257197-i9bucuma	281	85	Fe3O4	fe3o4	NN
cord-257197-i9bucuma	281	86	and	and	CC
cord-257197-i9bucuma	281	87	gamma	gamma	NN
cord-257197-i9bucuma	281	88	-	-	HYPH
cord-257197-i9bucuma	281	89	Fe2O3	fe2o3	NN
cord-257197-i9bucuma	281	90	particles	particle	NNS
cord-257197-i9bucuma	281	91	Quantitative	Quantitative	NNP
cord-257197-i9bucuma	281	92	Measurement	Measurement	NNP
cord-257197-i9bucuma	281	93	of	of	IN
cord-257197-i9bucuma	281	94	Ligand	Ligand	NNP
cord-257197-i9bucuma	281	95	Exchange	Exchange	NNP
cord-257197-i9bucuma	281	96	with	with	IN
cord-257197-i9bucuma	281	97	Small	Small	NNP
cord-257197-i9bucuma	281	98	-	-	HYPH
cord-257197-i9bucuma	281	99	Molecule	molecule	NN
cord-257197-i9bucuma	281	100	Ligands	Ligands	NNPS
cord-257197-i9bucuma	281	101	on	on	IN
cord-257197-i9bucuma	281	102	Iron	Iron	NNP
cord-257197-i9bucuma	281	103	Oxide	Oxide	NNP
cord-257197-i9bucuma	281	104	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	281	105	via	via	IN
cord-257197-i9bucuma	281	106	Radioanalytical	Radioanalytical	NNP
cord-257197-i9bucuma	281	107	Techniques	Techniques	NNP
cord-257197-i9bucuma	282	1	Current	current	JJ
cord-257197-i9bucuma	282	2	trends	trend	NNS
cord-257197-i9bucuma	282	3	in	in	IN
cord-257197-i9bucuma	282	4	using	use	VBG
cord-257197-i9bucuma	282	5	polymer	polymer	NN
cord-257197-i9bucuma	282	6	coated	coat	VBN
cord-257197-i9bucuma	282	7	gold	gold	NN
cord-257197-i9bucuma	282	8	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	282	9	for	for	IN
cord-257197-i9bucuma	282	10	cancer	cancer	NN
cord-257197-i9bucuma	282	11	therapy	therapy	NN
cord-257197-i9bucuma	282	12	Facile	Facile	NNP
cord-257197-i9bucuma	282	13	and	and	CC
cord-257197-i9bucuma	282	14	General	General	NNP
cord-257197-i9bucuma	282	15	Method	Method	NNP
cord-257197-i9bucuma	282	16	for	for	IN
cord-257197-i9bucuma	282	17	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	282	18	of	of	IN
cord-257197-i9bucuma	282	19	Sugar	Sugar	NNP
cord-257197-i9bucuma	282	20	Coated	Coated	NNP
cord-257197-i9bucuma	282	21	Gold	Gold	NNP
cord-257197-i9bucuma	282	22	Nanoparticles	Nanoparticles	NNP
cord-257197-i9bucuma	282	23	Hydroxide	Hydroxide	NNP
cord-257197-i9bucuma	282	24	assisted	assist	VBD
cord-257197-i9bucuma	282	25	synthesis	synthesis	NN
cord-257197-i9bucuma	282	26	of	of	IN
cord-257197-i9bucuma	282	27	monodisperse	monodisperse	NNP
cord-257197-i9bucuma	282	28	and	and	CC
cord-257197-i9bucuma	282	29	biocompatible	biocompatible	JJ
cord-257197-i9bucuma	282	30	gold	gold	NN
cord-257197-i9bucuma	282	31	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	282	32	with	with	IN
cord-257197-i9bucuma	282	33	dextran	dextran	NN
cord-257197-i9bucuma	282	34	A	a	DT
cord-257197-i9bucuma	282	35	simple	simple	JJ
cord-257197-i9bucuma	282	36	and	and	CC
cord-257197-i9bucuma	282	37	efficient	efficient	JJ
cord-257197-i9bucuma	282	38	method	method	NN
cord-257197-i9bucuma	282	39	for	for	IN
cord-257197-i9bucuma	282	40	polymer	polymer	NN
cord-257197-i9bucuma	282	41	coating	coating	NN
cord-257197-i9bucuma	282	42	of	of	IN
cord-257197-i9bucuma	282	43	iron	iron	NN
cord-257197-i9bucuma	282	44	oxide	oxide	NN
cord-257197-i9bucuma	282	45	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	282	46	Colloidal	Colloidal	NNP
cord-257197-i9bucuma	282	47	Stability	Stability	NNP
cord-257197-i9bucuma	282	48	of	of	IN
cord-257197-i9bucuma	282	49	Gold	Gold	NNP
cord-257197-i9bucuma	282	50	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	282	51	Modified	modify	VBN
cord-257197-i9bucuma	282	52	with	with	IN
cord-257197-i9bucuma	282	53	Thiol	Thiol	NNP
cord-257197-i9bucuma	282	54	Compounds	Compounds	NNPS
cord-257197-i9bucuma	282	55	:	:	:
cord-257197-i9bucuma	283	1	Bioconjugation	Bioconjugation	NNP
cord-257197-i9bucuma	283	2	and	and	CC
cord-257197-i9bucuma	283	3	Application	Application	NNP
cord-257197-i9bucuma	283	4	in	in	IN
cord-257197-i9bucuma	283	5	Cancer	Cancer	NNP
cord-257197-i9bucuma	283	6	Cell	Cell	NNP
cord-257197-i9bucuma	283	7	Imaging	Imaging	NNP
cord-257197-i9bucuma	283	8	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	283	9	and	and	CC
cord-257197-i9bucuma	283	10	characterization	characterization	NN
cord-257197-i9bucuma	283	11	of	of	IN
cord-257197-i9bucuma	283	12	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	283	13	iron	iron	NN
cord-257197-i9bucuma	283	14	oxide	oxide	NN
cord-257197-i9bucuma	283	15	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	283	16	as	as	IN
cord-257197-i9bucuma	283	17	calcium	calcium	NN
cord-257197-i9bucuma	283	18	-	-	HYPH
cord-257197-i9bucuma	283	19	responsive	responsive	JJ
cord-257197-i9bucuma	283	20	MRI	MRI	NNP
cord-257197-i9bucuma	283	21	contrast	contrast	NN
cord-257197-i9bucuma	283	22	agents	agent	NNS
cord-257197-i9bucuma	283	23	Smart	Smart	NNP
cord-257197-i9bucuma	283	24	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	283	25	for	for	IN
cord-257197-i9bucuma	283	26	Drug	Drug	NNP
cord-257197-i9bucuma	283	27	Delivery	Delivery	NNP
cord-257197-i9bucuma	283	28	Application	Application	NNP
cord-257197-i9bucuma	283	29	:	:	:
cord-257197-i9bucuma	283	30	Development	development	NN
cord-257197-i9bucuma	283	31	of	of	IN
cord-257197-i9bucuma	283	32	Versatile	Versatile	NNP
cord-257197-i9bucuma	283	33	Nanocarrier	Nanocarrier	NNP
cord-257197-i9bucuma	283	34	Platforms	Platforms	NNPS
cord-257197-i9bucuma	283	35	in	in	IN
cord-257197-i9bucuma	283	36	Biotechnology	Biotechnology	NNP
cord-257197-i9bucuma	283	37	and	and	CC
cord-257197-i9bucuma	283	38	Nanomedicine	Nanomedicine	NNP
cord-257197-i9bucuma	283	39	Approved	Approved	NNP
cord-257197-i9bucuma	283	40	Drug	Drug	NNP
cord-257197-i9bucuma	283	41	Products	Products	NNPS
cord-257197-i9bucuma	283	42	with	with	IN
cord-257197-i9bucuma	283	43	Therapeutic	therapeutic	JJ
cord-257197-i9bucuma	283	44	Equivalence	equivalence	NN
cord-257197-i9bucuma	283	45	Evaluations	evaluation	NNS
cord-257197-i9bucuma	283	46	Understanding	understand	VBG
cord-257197-i9bucuma	283	47	the	the	DT
cord-257197-i9bucuma	283	48	Nano	Nano	NNP
cord-257197-i9bucuma	283	49	-	-	HYPH
cord-257197-i9bucuma	283	50	bio	bio	NNP
cord-257197-i9bucuma	283	51	Interfaces	Interfaces	NNPS
cord-257197-i9bucuma	283	52	:	:	:
cord-257197-i9bucuma	283	53	Lipid	Lipid	NNP
cord-257197-i9bucuma	283	54	-	-	HYPH
cord-257197-i9bucuma	283	55	Coatings	Coatings	NNPS
cord-257197-i9bucuma	283	56	for	for	IN
cord-257197-i9bucuma	283	57	Inorganic	Inorganic	NNP
cord-257197-i9bucuma	283	58	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	283	59	as	as	IN
cord-257197-i9bucuma	283	60	Promising	Promising	NNP
cord-257197-i9bucuma	283	61	Strategy	Strategy	NNP
cord-257197-i9bucuma	283	62	for	for	IN
cord-257197-i9bucuma	283	63	Biomedical	Biomedical	NNP
cord-257197-i9bucuma	283	64	Applications	Applications	NNPS
cord-257197-i9bucuma	283	65	.	.	.
cord-257197-i9bucuma	284	1	Frontiers	frontier	NNS
cord-257197-i9bucuma	284	2	in	in	IN
cord-257197-i9bucuma	284	3	Chemistry	Chemistry	NNP
cord-257197-i9bucuma	284	4	Poly(ethylene	poly(ethylene	NN
cord-257197-i9bucuma	284	5	glycol)-lipid	glycol)-lipid	NNP
cord-257197-i9bucuma	284	6	conjugates	conjugate	NNS
cord-257197-i9bucuma	284	7	regulate	regulate	VBP
cord-257197-i9bucuma	284	8	the	the	DT
cord-257197-i9bucuma	284	9	calciuminduced	calciuminduced	JJ
cord-257197-i9bucuma	284	10	fusion	fusion	NN
cord-257197-i9bucuma	284	11	of	of	IN
cord-257197-i9bucuma	284	12	liposomes	liposome	NNS
cord-257197-i9bucuma	284	13	composed	compose	VBN
cord-257197-i9bucuma	284	14	of	of	IN
cord-257197-i9bucuma	284	15	phosphatidylethanolamine	phosphatidylethanolamine	NN
cord-257197-i9bucuma	284	16	and	and	CC
cord-257197-i9bucuma	284	17	phosphatidylserine	phosphatidylserine	NN
cord-257197-i9bucuma	284	18	Silicon	Silicon	NNP
cord-257197-i9bucuma	284	19	Quantum	Quantum	NNP
cord-257197-i9bucuma	284	20	Dots	Dots	NNPS
cord-257197-i9bucuma	284	21	Metal	metal	NN
cord-257197-i9bucuma	284	22	-	-	HYPH
cord-257197-i9bucuma	284	23	Enhanced	Enhanced	NNP
cord-257197-i9bucuma	284	24	Photoluminescence	Photoluminescence	NNP
cord-257197-i9bucuma	284	25	by	by	IN
cord-257197-i9bucuma	284	26	Gold	Gold	NNP
cord-257197-i9bucuma	284	27	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	284	28	in	in	IN
cord-257197-i9bucuma	284	29	Colloidal	Colloidal	NNP
cord-257197-i9bucuma	284	30	Ensembles	Ensembles	NNPS
cord-257197-i9bucuma	284	31	:	:	:
cord-257197-i9bucuma	284	32	Effect	effect	NN
cord-257197-i9bucuma	284	33	of	of	IN
cord-257197-i9bucuma	284	34	Surface	Surface	NNP
cord-257197-i9bucuma	284	35	Coating	Coating	NNP
cord-257197-i9bucuma	284	36	Cell	Cell	NNP
cord-257197-i9bucuma	284	37	-	-	HYPH
cord-257197-i9bucuma	284	38	Penetrating	Penetrating	NNP
cord-257197-i9bucuma	284	39	Peptide	Peptide	NNP
cord-257197-i9bucuma	284	40	-	-	HYPH
cord-257197-i9bucuma	284	41	Modified	modify	VBN
cord-257197-i9bucuma	284	42	Gold	Gold	NNP
cord-257197-i9bucuma	284	43	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	284	44	for	for	IN
cord-257197-i9bucuma	284	45	the	the	DT
cord-257197-i9bucuma	284	46	Delivery	Delivery	NNP
cord-257197-i9bucuma	284	47	of	of	IN
cord-257197-i9bucuma	284	48	Doxorubicin	Doxorubicin	NNP
cord-257197-i9bucuma	284	49	to	to	IN
cord-257197-i9bucuma	284	50	Brain	Brain	NNP
cord-257197-i9bucuma	284	51	Metastatic	Metastatic	NNP
cord-257197-i9bucuma	284	52	Breast	Breast	NNP
cord-257197-i9bucuma	284	53	Cancer	Cancer	NNP
cord-257197-i9bucuma	284	54	Synthesis	Synthesis	NNP
cord-257197-i9bucuma	284	55	and	and	CC
cord-257197-i9bucuma	284	56	in	in	IN
cord-257197-i9bucuma	284	57	vitro	vitro	FW
cord-257197-i9bucuma	284	58	evaluation	evaluation	NN
cord-257197-i9bucuma	284	59	of	of	IN
cord-257197-i9bucuma	284	60	fluorescent	fluorescent	NN
cord-257197-i9bucuma	284	61	and	and	CC
cord-257197-i9bucuma	284	62	magnetic	magnetic	JJ
cord-257197-i9bucuma	284	63	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	284	64	functionalized	functionalize	VBN
cord-257197-i9bucuma	284	65	with	with	IN
cord-257197-i9bucuma	284	66	a	a	DT
cord-257197-i9bucuma	284	67	cell	cell	NN
cord-257197-i9bucuma	284	68	penetrating	penetrate	VBG
cord-257197-i9bucuma	284	69	peptide	peptide	NN
cord-257197-i9bucuma	284	70	for	for	IN
cord-257197-i9bucuma	284	71	cancer	cancer	NN
cord-257197-i9bucuma	284	72	theranosis	theranosis	NNP
cord-257197-i9bucuma	284	73	Penetratin	Penetratin	NNP
cord-257197-i9bucuma	284	74	Peptide	Peptide	NNP
cord-257197-i9bucuma	284	75	-	-	HYPH
cord-257197-i9bucuma	284	76	Functionalized	Functionalized	NNP
cord-257197-i9bucuma	284	77	Gold	Gold	NNP
cord-257197-i9bucuma	284	78	Nanostars	Nanostars	NNPS
cord-257197-i9bucuma	284	79	:	:	:
cord-257197-i9bucuma	284	80	Enhanced	enhanced	JJ
cord-257197-i9bucuma	284	81	BBB	BBB	NNP
cord-257197-i9bucuma	284	82	Permeability	Permeability	NNP
cord-257197-i9bucuma	284	83	and	and	CC
cord-257197-i9bucuma	284	84	NIR	NIR	NNP
cord-257197-i9bucuma	284	85	Photothermal	Photothermal	NNP
cord-257197-i9bucuma	284	86	Treatment	Treatment	NNP
cord-257197-i9bucuma	284	87	of	of	IN
cord-257197-i9bucuma	284	88	Alzheimer	Alzheimer	NNP
cord-257197-i9bucuma	284	89	's	's	POS
cord-257197-i9bucuma	284	90	Disease	Disease	NNP
cord-257197-i9bucuma	284	91	Using	use	VBG
cord-257197-i9bucuma	284	92	Ultralow	Ultralow	NNP
cord-257197-i9bucuma	284	93	Irradiance	Irradiance	NNP
cord-257197-i9bucuma	284	94	Biocompatible	Biocompatible	NNP
cord-257197-i9bucuma	284	95	Peptide	Peptide	NNP
cord-257197-i9bucuma	284	96	-	-	HYPH
cord-257197-i9bucuma	284	97	Coated	Coated	NNP
cord-257197-i9bucuma	284	98	Ultrasmall	Ultrasmall	NNP
cord-257197-i9bucuma	284	99	Superparamagnetic	Superparamagnetic	NNP
cord-257197-i9bucuma	284	100	Iron	Iron	NNP
cord-257197-i9bucuma	284	101	Oxide	oxide	NN
cord-257197-i9bucuma	284	102	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	284	103	for	for	IN
cord-257197-i9bucuma	285	1	In	in	IN
cord-257197-i9bucuma	285	2	Vivo	Vivo	NNP
cord-257197-i9bucuma	286	1	Contrast	contrast	NN
cord-257197-i9bucuma	286	2	-	-	HYPH
cord-257197-i9bucuma	286	3	Enhanced	Enhanced	NNP
cord-257197-i9bucuma	286	4	Magnetic	Magnetic	NNP
cord-257197-i9bucuma	286	5	Resonance	Resonance	NNP
cord-257197-i9bucuma	286	6	Imaging	Imaging	NNP
cord-257197-i9bucuma	286	7	A	A	NNP
cord-257197-i9bucuma	286	8	Study	Study	NNP
cord-257197-i9bucuma	286	9	of	of	IN
cord-257197-i9bucuma	286	10	the	the	DT
cord-257197-i9bucuma	286	11	Cellular	Cellular	NNP
cord-257197-i9bucuma	286	12	Uptake	Uptake	NNP
cord-257197-i9bucuma	286	13	of	of	IN
cord-257197-i9bucuma	287	1	Magnetic	Magnetic	NNP
cord-257197-i9bucuma	287	2	Branched	Branched	NNP
cord-257197-i9bucuma	287	3	Amphiphilic	Amphiphilic	NNP
cord-257197-i9bucuma	287	4	Peptide	Peptide	NNP
cord-257197-i9bucuma	287	5	Capsules	Capsules	NNPS
cord-257197-i9bucuma	287	6	Protein	Protein	NNP
cord-257197-i9bucuma	287	7	coated	coat	VBD
cord-257197-i9bucuma	287	8	gold	gold	NN
cord-257197-i9bucuma	287	9	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	287	10	as	as	IN
cord-257197-i9bucuma	287	11	template	template	NN
cord-257197-i9bucuma	287	12	for	for	IN
cord-257197-i9bucuma	287	13	the	the	DT
cord-257197-i9bucuma	287	14	directed	direct	VBN
cord-257197-i9bucuma	287	15	synthesis	synthesis	NN
cord-257197-i9bucuma	287	16	of	of	IN
cord-257197-i9bucuma	287	17	highly	highly	RB
cord-257197-i9bucuma	287	18	fluorescent	fluorescent	JJ
cord-257197-i9bucuma	287	19	gold	gold	NN
cord-257197-i9bucuma	287	20	nanoclusters	nanocluster	NNS
cord-257197-i9bucuma	287	21	Bovine	Bovine	NNP
cord-257197-i9bucuma	287	22	Serum	Serum	NNP
cord-257197-i9bucuma	287	23	Albumin	Albumin	NNP
cord-257197-i9bucuma	287	24	(	(	-LRB-
cord-257197-i9bucuma	287	25	BSA	BSA	NNP
cord-257197-i9bucuma	287	26	)	)	-RRB-
cord-257197-i9bucuma	287	27	coated	coat	VBD
cord-257197-i9bucuma	287	28	iron	iron	NN
cord-257197-i9bucuma	287	29	oxide	oxide	NN
cord-257197-i9bucuma	287	30	magnetic	magnetic	JJ
cord-257197-i9bucuma	287	31	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	287	32	as	as	IN
cord-257197-i9bucuma	287	33	biocompatible	biocompatible	JJ
cord-257197-i9bucuma	287	34	carriers	carrier	NNS
cord-257197-i9bucuma	287	35	for	for	IN
cord-257197-i9bucuma	287	36	curcumin	curcumin	NN
cord-257197-i9bucuma	287	37	-	-	HYPH
cord-257197-i9bucuma	287	38	anticancer	anticancer	NN
cord-257197-i9bucuma	287	39	drug	drug	NN
cord-257197-i9bucuma	287	40	Increased	increase	VBN
cord-257197-i9bucuma	287	41	Survival	Survival	NNP
cord-257197-i9bucuma	287	42	in	in	IN
cord-257197-i9bucuma	287	43	Pancreatic	pancreatic	JJ
cord-257197-i9bucuma	287	44	Cancer	Cancer	NNP
cord-257197-i9bucuma	287	45	with	with	IN
cord-257197-i9bucuma	287	46	nab	nab	NNPS
cord-257197-i9bucuma	287	47	-	-	HYPH
cord-257197-i9bucuma	287	48	Paclitaxel	Paclitaxel	NNP
cord-257197-i9bucuma	287	49	plus	plus	CC
cord-257197-i9bucuma	287	50	Gemcitabine	Gemcitabine	NNP
cord-257197-i9bucuma	287	51	Multiresponsive	Multiresponsive	NNP
cord-257197-i9bucuma	287	52	albumin	albumin	NN
cord-257197-i9bucuma	287	53	-	-	HYPH
cord-257197-i9bucuma	287	54	lonidamine	lonidamine	NN
cord-257197-i9bucuma	287	55	conjugated	conjugate	VBN
cord-257197-i9bucuma	287	56	hybridized	hybridize	VBN
cord-257197-i9bucuma	287	57	gold	gold	NN
cord-257197-i9bucuma	287	58	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	287	59	as	as	IN
cord-257197-i9bucuma	287	60	a	a	DT
cord-257197-i9bucuma	287	61	combined	combine	VBN
cord-257197-i9bucuma	287	62	photothermal	photothermal	NN
cord-257197-i9bucuma	287	63	-	-	HYPH
cord-257197-i9bucuma	287	64	chemotherapy	chemotherapy	NN
cord-257197-i9bucuma	287	65	for	for	IN
cord-257197-i9bucuma	287	66	synergistic	synergistic	JJ
cord-257197-i9bucuma	287	67	tumor	tumor	NN
cord-257197-i9bucuma	287	68	ablation	ablation	NN
cord-257197-i9bucuma	288	1	Acquired	Acquired	NNP
cord-257197-i9bucuma	288	2	Resistance	Resistance	NNP
cord-257197-i9bucuma	288	3	to	to	IN
cord-257197-i9bucuma	288	4	Antibody	Antibody	NNP
cord-257197-i9bucuma	288	5	-	-	HYPH
cord-257197-i9bucuma	288	6	Drug	Drug	NNP
cord-257197-i9bucuma	288	7	Conjugates	Conjugates	NNPS
cord-257197-i9bucuma	288	8	Anti	Anti	NNP
cord-257197-i9bucuma	288	9	-	-	JJ
cord-257197-i9bucuma	288	10	HER2	her2	JJ
cord-257197-i9bucuma	288	11	antibody	antibody	NN
cord-257197-i9bucuma	288	12	and	and	CC
cord-257197-i9bucuma	288	13	ScFvEGFR	scfvegfr	NN
cord-257197-i9bucuma	288	14	-	-	HYPH
cord-257197-i9bucuma	288	15	conjugated	conjugate	VBN
cord-257197-i9bucuma	288	16	antifouling	antifouling	NN
cord-257197-i9bucuma	288	17	magnetic	magnetic	JJ
cord-257197-i9bucuma	288	18	iron	iron	NN
cord-257197-i9bucuma	288	19	oxide	oxide	NN
cord-257197-i9bucuma	288	20	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	288	21	for	for	IN
cord-257197-i9bucuma	288	22	targeting	target	VBG
cord-257197-i9bucuma	288	23	and	and	CC
cord-257197-i9bucuma	288	24	magnetic	magnetic	JJ
cord-257197-i9bucuma	288	25	resonance	resonance	NN
cord-257197-i9bucuma	288	26	imaging	imaging	NN
cord-257197-i9bucuma	288	27	of	of	IN
cord-257197-i9bucuma	288	28	breast	breast	NN
cord-257197-i9bucuma	288	29	cancer	cancer	NN
cord-257197-i9bucuma	288	30	Impact	impact	NN
cord-257197-i9bucuma	288	31	of	of	IN
cord-257197-i9bucuma	288	32	conjugation	conjugation	NN
cord-257197-i9bucuma	288	33	strategies	strategy	NNS
cord-257197-i9bucuma	288	34	for	for	IN
cord-257197-i9bucuma	288	35	targeting	target	VBG
cord-257197-i9bucuma	288	36	of	of	IN
cord-257197-i9bucuma	288	37	antibodies	antibody	NNS
cord-257197-i9bucuma	288	38	in	in	IN
cord-257197-i9bucuma	288	39	gold	gold	NN
cord-257197-i9bucuma	288	40	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	288	41	for	for	IN
cord-257197-i9bucuma	288	42	ultrasensitive	ultrasensitive	JJ
cord-257197-i9bucuma	288	43	detection	detection	NN
cord-257197-i9bucuma	288	44	of	of	IN
cord-257197-i9bucuma	288	45	17	17	CD
cord-257197-i9bucuma	288	46	beta	beta	NN
cord-257197-i9bucuma	288	47	-	-	HYPH
cord-257197-i9bucuma	288	48	estradiol	estradiol	NN
cord-257197-i9bucuma	288	49	Click	click	NN
cord-257197-i9bucuma	288	50	Chemistry	chemistry	NN
cord-257197-i9bucuma	288	51	Immobilization	immobilization	NN
cord-257197-i9bucuma	288	52	of	of	IN
cord-257197-i9bucuma	288	53	Antibodies	Antibodies	NNPS
cord-257197-i9bucuma	288	54	on	on	IN
cord-257197-i9bucuma	288	55	Polymer	Polymer	NNP
cord-257197-i9bucuma	288	56	Coated	Coated	NNP
cord-257197-i9bucuma	288	57	Gold	Gold	NNP
cord-257197-i9bucuma	288	58	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	289	1	A	a	DT
cord-257197-i9bucuma	289	2	novel	novel	JJ
cord-257197-i9bucuma	289	3	immuno	immuno	JJ
cord-257197-i9bucuma	289	4	-	-	JJ
cord-257197-i9bucuma	289	5	gold	gold	JJ
cord-257197-i9bucuma	289	6	labeling	labeling	NN
cord-257197-i9bucuma	289	7	protocol	protocol	NN
cord-257197-i9bucuma	289	8	for	for	IN
cord-257197-i9bucuma	289	9	nanobody	nanobody	NN
cord-257197-i9bucuma	289	10	-	-	HYPH
cord-257197-i9bucuma	289	11	based	base	VBN
cord-257197-i9bucuma	289	12	detection	detection	NN
cord-257197-i9bucuma	289	13	of	of	IN
cord-257197-i9bucuma	289	14	HER2	HER2	NNP
cord-257197-i9bucuma	289	15	in	in	IN
cord-257197-i9bucuma	289	16	breast	breast	NN
cord-257197-i9bucuma	289	17	cancer	cancer	NN
cord-257197-i9bucuma	289	18	cells	cell	NNS
cord-257197-i9bucuma	289	19	using	use	VBG
cord-257197-i9bucuma	289	20	immuno	immuno	JJ
cord-257197-i9bucuma	289	21	-	-	HYPH
cord-257197-i9bucuma	289	22	electron	electron	NN
cord-257197-i9bucuma	289	23	microscopy	microscopy	NN
cord-257197-i9bucuma	289	24	Surface	surface	NN
cord-257197-i9bucuma	289	25	plasmon	plasmon	JJ
cord-257197-i9bucuma	289	26	resonance	resonance	NN
cord-257197-i9bucuma	289	27	scattering	scattering	NN
cord-257197-i9bucuma	289	28	and	and	CC
cord-257197-i9bucuma	289	29	absorption	absorption	NN
cord-257197-i9bucuma	289	30	of	of	IN
cord-257197-i9bucuma	289	31	anti	anti	JJ
cord-257197-i9bucuma	289	32	-	-	JJ
cord-257197-i9bucuma	289	33	EGFR	egfr	JJ
cord-257197-i9bucuma	289	34	antibody	antibody	NN
cord-257197-i9bucuma	289	35	conjugated	conjugate	VBD
cord-257197-i9bucuma	289	36	gold	gold	NN
cord-257197-i9bucuma	289	37	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	289	38	in	in	IN
cord-257197-i9bucuma	289	39	cancer	cancer	NN
cord-257197-i9bucuma	289	40	diagnostics	diagnostic	NNS
cord-257197-i9bucuma	289	41	:	:	:
cord-257197-i9bucuma	290	1	Applications	application	NNS
cord-257197-i9bucuma	290	2	in	in	IN
cord-257197-i9bucuma	290	3	oral	oral	JJ
cord-257197-i9bucuma	290	4	cancer	cancer	NN
cord-257197-i9bucuma	290	5	DNA	dna	NN
cord-257197-i9bucuma	290	6	-	-	HYPH
cord-257197-i9bucuma	290	7	Grafted	grafted	JJ
cord-257197-i9bucuma	290	8	Poly(acrylic	poly(acrylic	NN
cord-257197-i9bucuma	290	9	acid	acid	NN
cord-257197-i9bucuma	290	10	)	)	-RRB-
cord-257197-i9bucuma	290	11	for	for	IN
cord-257197-i9bucuma	290	12	One	one	CD
cord-257197-i9bucuma	290	13	-	-	HYPH
cord-257197-i9bucuma	290	14	Step	step	NN
cord-257197-i9bucuma	290	15	DNA	dna	NN
cord-257197-i9bucuma	290	16	Functionalization	Functionalization	NNP
cord-257197-i9bucuma	290	17	of	of	IN
cord-257197-i9bucuma	290	18	Iron	Iron	NNP
cord-257197-i9bucuma	290	19	Oxide	Oxide	NNP
cord-257197-i9bucuma	290	20	Nanoparticles	Nanoparticles	NNP
cord-257197-i9bucuma	290	21	Binding	bind	VBG
cord-257197-i9bucuma	290	22	of	of	IN
cord-257197-i9bucuma	290	23	single	single	JJ
cord-257197-i9bucuma	290	24	stranded	strand	VBN
cord-257197-i9bucuma	290	25	nucleic	nucleic	JJ
cord-257197-i9bucuma	290	26	acids	acid	NNS
cord-257197-i9bucuma	290	27	to	to	IN
cord-257197-i9bucuma	290	28	cationic	cationic	JJ
cord-257197-i9bucuma	290	29	ligand	ligand	NN
cord-257197-i9bucuma	290	30	functionalized	functionalize	VBN
cord-257197-i9bucuma	290	31	gold	gold	NN
cord-257197-i9bucuma	290	32	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	291	1	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	291	2	Enable	enable	VBP
cord-257197-i9bucuma	291	3	Efficient	efficient	JJ
cord-257197-i9bucuma	291	4	Delivery	Delivery	NNP
cord-257197-i9bucuma	291	5	of	of	IN
cord-257197-i9bucuma	291	6	Therapeutic	Therapeutic	NNP
cord-257197-i9bucuma	291	7	siRNA	siRNA	NNP
cord-257197-i9bucuma	292	1	Targeting	target	VBG
cord-257197-i9bucuma	292	2	REST	rest	NN
cord-257197-i9bucuma	292	3	into	into	IN
cord-257197-i9bucuma	292	4	Glioblastoma	Glioblastoma	NNP
cord-257197-i9bucuma	292	5	Cells	cell	NNS
cord-257197-i9bucuma	293	1	Superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	293	2	iron	iron	NN
cord-257197-i9bucuma	293	3	oxide	oxide	NN
cord-257197-i9bucuma	293	4	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	293	5	functionalized	functionalize	VBN
cord-257197-i9bucuma	293	6	by	by	IN
cord-257197-i9bucuma	293	7	peptide	peptide	NN
cord-257197-i9bucuma	293	8	nucleic	nucleic	JJ
cord-257197-i9bucuma	293	9	acids	acid	NNS
cord-257197-i9bucuma	293	10	Nucleic	nucleic	VBP
cord-257197-i9bucuma	293	11	acid	acid	NN
cord-257197-i9bucuma	293	12	and	and	CC
cord-257197-i9bucuma	293	13	nucleotide	nucleotide	NN
cord-257197-i9bucuma	293	14	-	-	HYPH
cord-257197-i9bucuma	293	15	mediated	mediate	VBN
cord-257197-i9bucuma	293	16	synthesis	synthesis	NN
cord-257197-i9bucuma	293	17	of	of	IN
cord-257197-i9bucuma	293	18	inorganic	inorganic	JJ
cord-257197-i9bucuma	293	19	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	293	20	Gold	Gold	NNP
cord-257197-i9bucuma	293	21	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	293	22	-	-	HYPH
cord-257197-i9bucuma	293	23	Aptamer	Aptamer	NNP
cord-257197-i9bucuma	293	24	-	-	HYPH
cord-257197-i9bucuma	293	25	Based	base	VBN
cord-257197-i9bucuma	293	26	LSPR	LSPR	NNP
cord-257197-i9bucuma	293	27	Sensing	Sensing	NNP
cord-257197-i9bucuma	293	28	of	of	IN
cord-257197-i9bucuma	293	29	Ochratoxin	Ochratoxin	NNP
cord-257197-i9bucuma	293	30	A	A	NNP
cord-257197-i9bucuma	293	31	at	at	IN
cord-257197-i9bucuma	293	32	a	a	DT
cord-257197-i9bucuma	293	33	Widened	Widened	NNP
cord-257197-i9bucuma	293	34	Detection	detection	NN
cord-257197-i9bucuma	293	35	Range	Range	NNP
cord-257197-i9bucuma	293	36	by	by	IN
cord-257197-i9bucuma	293	37	Double	Double	NNP
cord-257197-i9bucuma	293	38	Calibration	Calibration	NNP
cord-257197-i9bucuma	293	39	Curve	curve	NN
cord-257197-i9bucuma	293	40	Method	Method	NNP
cord-257197-i9bucuma	293	41	Aptamer	Aptamer	NNP
cord-257197-i9bucuma	293	42	-	-	HYPH
cord-257197-i9bucuma	293	43	modified	modify	VBN
cord-257197-i9bucuma	293	44	gold	gold	NN
cord-257197-i9bucuma	293	45	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	293	46	for	for	IN
cord-257197-i9bucuma	293	47	colorimetric	colorimetric	JJ
cord-257197-i9bucuma	293	48	determination	determination	NN
cord-257197-i9bucuma	293	49	of	of	IN
cord-257197-i9bucuma	293	50	platelet	platelet	NN
cord-257197-i9bucuma	293	51	-	-	HYPH
cord-257197-i9bucuma	293	52	derived	derive	VBN
cord-257197-i9bucuma	293	53	growth	growth	NN
cord-257197-i9bucuma	293	54	factors	factor	NNS
cord-257197-i9bucuma	293	55	and	and	CC
cord-257197-i9bucuma	293	56	their	-PRON-	PRP$
cord-257197-i9bucuma	293	57	receptors	receptor	NNS
cord-257197-i9bucuma	293	58	Disposable	disposable	JJ
cord-257197-i9bucuma	293	59	aptamer	aptamer	JJ
cord-257197-i9bucuma	293	60	-	-	HYPH
cord-257197-i9bucuma	293	61	sensor	sensor	NN
cord-257197-i9bucuma	293	62	aided	aid	VBN
cord-257197-i9bucuma	293	63	by	by	IN
cord-257197-i9bucuma	293	64	magnetic	magnetic	JJ
cord-257197-i9bucuma	293	65	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	293	66	enrichment	enrichment	NN
cord-257197-i9bucuma	293	67	for	for	IN
cord-257197-i9bucuma	293	68	detection	detection	NN
cord-257197-i9bucuma	293	69	of	of	IN
cord-257197-i9bucuma	293	70	salivary	salivary	JJ
cord-257197-i9bucuma	293	71	cortisol	cortisol	NN
cord-257197-i9bucuma	293	72	variations	variation	NNS
cord-257197-i9bucuma	293	73	in	in	IN
cord-257197-i9bucuma	293	74	obstructive	obstructive	JJ
cord-257197-i9bucuma	293	75	sleep	sleep	NN
cord-257197-i9bucuma	293	76	apnea	apnea	NN
cord-257197-i9bucuma	293	77	patients	patient	NNS
cord-257197-i9bucuma	293	78	Dose-	dose-	IN
cord-257197-i9bucuma	293	79	,	,	,
cord-257197-i9bucuma	293	80	treatment	treatment	NN
cord-257197-i9bucuma	293	81	-	-	HYPH
cord-257197-i9bucuma	293	82	and	and	CC
cord-257197-i9bucuma	293	83	time	time	NN
cord-257197-i9bucuma	293	84	-	-	HYPH
cord-257197-i9bucuma	293	85	dependent	dependent	JJ
cord-257197-i9bucuma	293	86	toxicity	toxicity	NN
cord-257197-i9bucuma	293	87	of	of	IN
cord-257197-i9bucuma	293	88	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	293	89	iron	iron	NN
cord-257197-i9bucuma	293	90	oxide	oxide	NN
cord-257197-i9bucuma	293	91	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	293	92	on	on	IN
cord-257197-i9bucuma	293	93	primary	primary	JJ
cord-257197-i9bucuma	293	94	rat	rat	NN
cord-257197-i9bucuma	293	95	hepatocytes	hepatocyte	VBZ
cord-257197-i9bucuma	293	96	Biodistribution	Biodistribution	NNP
cord-257197-i9bucuma	293	97	and	and	CC
cord-257197-i9bucuma	293	98	toxicity	toxicity	NN
cord-257197-i9bucuma	293	99	of	of	IN
cord-257197-i9bucuma	293	100	engineered	engineer	VBN
cord-257197-i9bucuma	293	101	gold	gold	NN
cord-257197-i9bucuma	293	102	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	293	103	:	:	:
cord-257197-i9bucuma	294	1	a	a	DT
cord-257197-i9bucuma	294	2	review	review	NN
cord-257197-i9bucuma	294	3	of	of	IN
cord-257197-i9bucuma	294	4	in	in	FW
cord-257197-i9bucuma	294	5	vitro	vitro	FW
cord-257197-i9bucuma	294	6	and	and	CC
cord-257197-i9bucuma	294	7	in	in	IN
cord-257197-i9bucuma	294	8	vivo	vivo	NNP
cord-257197-i9bucuma	294	9	studies	study	NNS
cord-257197-i9bucuma	294	10	Gold	gold	NN
cord-257197-i9bucuma	294	11	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	294	12	:	:	:
cord-257197-i9bucuma	294	13	Distribution	distribution	NN
cord-257197-i9bucuma	294	14	,	,	,
cord-257197-i9bucuma	294	15	bioaccumulation	bioaccumulation	NN
cord-257197-i9bucuma	294	16	and	and	CC
cord-257197-i9bucuma	294	17	toxicity	toxicity	NN
cord-257197-i9bucuma	294	18	.	.	.
cord-257197-i9bucuma	295	1	In	in	IN
cord-257197-i9bucuma	295	2	vitro	vitro	FW
cord-257197-i9bucuma	295	3	and	and	CC
cord-257197-i9bucuma	295	4	in	in	IN
cord-257197-i9bucuma	295	5	vivo	vivo	NNP
cord-257197-i9bucuma	295	6	studies	study	NNS
cord-257197-i9bucuma	295	7	Assessing	assess	VBG
cord-257197-i9bucuma	295	8	cell	cell	NN
cord-257197-i9bucuma	295	9	-	-	HYPH
cord-257197-i9bucuma	295	10	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	295	11	interactions	interaction	NNS
cord-257197-i9bucuma	295	12	by	by	IN
cord-257197-i9bucuma	295	13	high	high	JJ
cord-257197-i9bucuma	295	14	content	content	NN
cord-257197-i9bucuma	295	15	imaging	imaging	NN
cord-257197-i9bucuma	295	16	of	of	IN
cord-257197-i9bucuma	295	17	biocompatible	biocompatible	JJ
cord-257197-i9bucuma	295	18	iron	iron	NN
cord-257197-i9bucuma	295	19	oxide	oxide	NN
cord-257197-i9bucuma	295	20	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	295	21	as	as	IN
cord-257197-i9bucuma	295	22	potential	potential	JJ
cord-257197-i9bucuma	295	23	contrast	contrast	NN
cord-257197-i9bucuma	295	24	agents	agent	NNS
cord-257197-i9bucuma	295	25	for	for	IN
cord-257197-i9bucuma	295	26	magnetic	magnetic	JJ
cord-257197-i9bucuma	295	27	resonance	resonance	NN
cord-257197-i9bucuma	295	28	imaging	imaging	NN
cord-257197-i9bucuma	295	29	Natural	natural	JJ
cord-257197-i9bucuma	295	30	tripeptide	tripeptide	NN
cord-257197-i9bucuma	295	31	capped	cap	VBN
cord-257197-i9bucuma	295	32	pH	ph	JJ
cord-257197-i9bucuma	295	33	-	-	HYPH
cord-257197-i9bucuma	295	34	sensitive	sensitive	JJ
cord-257197-i9bucuma	295	35	gold	gold	NN
cord-257197-i9bucuma	295	36	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	295	37	for	for	IN
cord-257197-i9bucuma	295	38	efficacious	efficacious	JJ
cord-257197-i9bucuma	295	39	doxorubicin	doxorubicin	JJ
cord-257197-i9bucuma	295	40	delivery	delivery	NN
cord-257197-i9bucuma	295	41	both	both	CC
cord-257197-i9bucuma	295	42	in	in	IN
cord-257197-i9bucuma	295	43	vitro	vitro	FW
cord-257197-i9bucuma	295	44	and	and	CC
cord-257197-i9bucuma	295	45	in	in	IN
cord-257197-i9bucuma	295	46	vivo	vivo	NNP
cord-257197-i9bucuma	295	47	Effect	effect	NN
cord-257197-i9bucuma	295	48	of	of	IN
cord-257197-i9bucuma	295	49	Surface	Surface	NNP
cord-257197-i9bucuma	295	50	Chemistry	Chemistry	NNP
cord-257197-i9bucuma	295	51	and	and	CC
cord-257197-i9bucuma	295	52	Associated	Associated	NNP
cord-257197-i9bucuma	295	53	Protein	Protein	NNP
cord-257197-i9bucuma	295	54	Corona	Corona	NNP
cord-257197-i9bucuma	295	55	on	on	IN
cord-257197-i9bucuma	295	56	the	the	DT
cord-257197-i9bucuma	295	57	Long	Long	NNP
cord-257197-i9bucuma	295	58	-	-	HYPH
cord-257197-i9bucuma	295	59	Term	term	NN
cord-257197-i9bucuma	295	60	Biodegradation	Biodegradation	NNP
cord-257197-i9bucuma	295	61	of	of	IN
cord-257197-i9bucuma	295	62	Iron	Iron	NNP
cord-257197-i9bucuma	295	63	Oxide	oxide	NN
cord-257197-i9bucuma	295	64	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	296	1	In	in	IN
cord-257197-i9bucuma	296	2	Vivo	Vivo	NNP
cord-257197-i9bucuma	296	3	A	a	DT
cord-257197-i9bucuma	296	4	Systematic	systematic	JJ
cord-257197-i9bucuma	296	5	comparison	comparison	NN
cord-257197-i9bucuma	296	6	of	of	IN
cord-257197-i9bucuma	296	7	in	in	FW
cord-257197-i9bucuma	296	8	vitro	vitro	FW
cord-257197-i9bucuma	296	9	cell	cell	NN
cord-257197-i9bucuma	296	10	uptake	uptake	NN
cord-257197-i9bucuma	296	11	and	and	CC
cord-257197-i9bucuma	296	12	in	in	IN
cord-257197-i9bucuma	296	13	vivo	vivo	NN
cord-257197-i9bucuma	296	14	biodistribution	biodistribution	NN
cord-257197-i9bucuma	296	15	for	for	IN
cord-257197-i9bucuma	296	16	three	three	CD
cord-257197-i9bucuma	296	17	classes	class	NNS
cord-257197-i9bucuma	296	18	of	of	IN
cord-257197-i9bucuma	296	19	gold	gold	NN
cord-257197-i9bucuma	296	20	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	296	21	with	with	IN
cord-257197-i9bucuma	296	22	saturated	saturated	JJ
cord-257197-i9bucuma	296	23	PEG	peg	NN
cord-257197-i9bucuma	296	24	coatings	coating	NNS
cord-257197-i9bucuma	296	25	Uptake	uptake	NN
cord-257197-i9bucuma	296	26	,	,	,
cord-257197-i9bucuma	296	27	distribution	distribution	NN
cord-257197-i9bucuma	296	28	,	,	,
cord-257197-i9bucuma	296	29	clearance	clearance	NN
cord-257197-i9bucuma	296	30	,	,	,
cord-257197-i9bucuma	296	31	and	and	CC
cord-257197-i9bucuma	296	32	toxicity	toxicity	NN
cord-257197-i9bucuma	296	33	of	of	IN
cord-257197-i9bucuma	296	34	iron	iron	NN
cord-257197-i9bucuma	296	35	oxide	oxide	NN
cord-257197-i9bucuma	296	36	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	296	37	with	with	IN
cord-257197-i9bucuma	296	38	different	different	JJ
cord-257197-i9bucuma	296	39	sizes	size	NNS
cord-257197-i9bucuma	296	40	and	and	CC
cord-257197-i9bucuma	296	41	coatings	coating	NNS
cord-257197-i9bucuma	296	42	Cellular	cellular	JJ
cord-257197-i9bucuma	296	43	uptake	uptake	NN
cord-257197-i9bucuma	296	44	of	of	IN
cord-257197-i9bucuma	296	45	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	296	46	:	:	:
cord-257197-i9bucuma	296	47	journey	journey	VB
cord-257197-i9bucuma	296	48	inside	inside	IN
cord-257197-i9bucuma	296	49	the	the	DT
cord-257197-i9bucuma	296	50	cell	cell	NN
cord-257197-i9bucuma	297	1	Parametrizing	parametrize	VBG
cord-257197-i9bucuma	297	2	the	the	DT
cord-257197-i9bucuma	297	3	exposure	exposure	NN
cord-257197-i9bucuma	297	4	of	of	IN
cord-257197-i9bucuma	297	5	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	297	6	iron	iron	NN
cord-257197-i9bucuma	297	7	oxide	oxide	NN
cord-257197-i9bucuma	297	8	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	297	9	in	in	IN
cord-257197-i9bucuma	297	10	cell	cell	NN
cord-257197-i9bucuma	297	11	cultures	culture	NNS
cord-257197-i9bucuma	297	12	at	at	IN
cord-257197-i9bucuma	297	13	different	different	JJ
cord-257197-i9bucuma	297	14	in	in	IN
cord-257197-i9bucuma	297	15	vitro	vitro	FW
cord-257197-i9bucuma	297	16	environments	environment	NNS
cord-257197-i9bucuma	298	1	Effects	effect	NNS
cord-257197-i9bucuma	298	2	of	of	IN
cord-257197-i9bucuma	298	3	Cell	cell	NN
cord-257197-i9bucuma	298	4	Culture	culture	NN
cord-257197-i9bucuma	298	5	Media	medium	NNS
cord-257197-i9bucuma	298	6	on	on	IN
cord-257197-i9bucuma	298	7	the	the	DT
cord-257197-i9bucuma	298	8	Dynamic	Dynamic	NNP
cord-257197-i9bucuma	298	9	Formation	Formation	NNP
cord-257197-i9bucuma	298	10	of	of	IN
cord-257197-i9bucuma	298	11	Protein	Protein	NNP
cord-257197-i9bucuma	298	12	-	-	HYPH
cord-257197-i9bucuma	298	13	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	298	14	Complexes	Complexes	NNPS
cord-257197-i9bucuma	298	15	and	and	CC
cord-257197-i9bucuma	298	16	Influence	Influence	NNP
cord-257197-i9bucuma	298	17	on	on	IN
cord-257197-i9bucuma	298	18	the	the	DT
cord-257197-i9bucuma	298	19	Cellular	Cellular	NNP
cord-257197-i9bucuma	298	20	Response	Response	NNP
cord-257197-i9bucuma	298	21	Functionalized	Functionalized	NNP
cord-257197-i9bucuma	298	22	Gold	Gold	NNP
cord-257197-i9bucuma	298	23	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	298	24	as	as	IN
cord-257197-i9bucuma	298	25	Biosensors	Biosensors	NNPS
cord-257197-i9bucuma	298	26	for	for	IN
cord-257197-i9bucuma	298	27	Monitoring	Monitoring	NNP
cord-257197-i9bucuma	298	28	Cellular	Cellular	NNP
cord-257197-i9bucuma	298	29	Uptake	Uptake	NNP
cord-257197-i9bucuma	298	30	and	and	CC
cord-257197-i9bucuma	298	31	Localization	Localization	NNP
cord-257197-i9bucuma	298	32	in	in	IN
cord-257197-i9bucuma	298	33	Normal	normal	JJ
cord-257197-i9bucuma	298	34	and	and	CC
cord-257197-i9bucuma	298	35	Tumor	tumor	NN
cord-257197-i9bucuma	298	36	Prostatic	Prostatic	NNP
cord-257197-i9bucuma	298	37	Cells	Cells	NNP
cord-257197-i9bucuma	298	38	Selection	Selection	NNP
cord-257197-i9bucuma	298	39	of	of	IN
cord-257197-i9bucuma	298	40	potential	potential	JJ
cord-257197-i9bucuma	298	41	iron	iron	NN
cord-257197-i9bucuma	298	42	oxide	oxide	NN
cord-257197-i9bucuma	298	43	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	298	44	for	for	IN
cord-257197-i9bucuma	298	45	breast	breast	NN
cord-257197-i9bucuma	298	46	cancer	cancer	NN
cord-257197-i9bucuma	298	47	treatment	treatment	NN
cord-257197-i9bucuma	298	48	based	base	VBN
cord-257197-i9bucuma	298	49	on	on	IN
cord-257197-i9bucuma	298	50	in	in	IN
cord-257197-i9bucuma	298	51	vitro	vitro	FW
cord-257197-i9bucuma	298	52	cytotoxicity	cytotoxicity	NN
cord-257197-i9bucuma	298	53	and	and	CC
cord-257197-i9bucuma	298	54	cellular	cellular	JJ
cord-257197-i9bucuma	298	55	uptake	uptake	NN
cord-257197-i9bucuma	298	56	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	298	57	administration	administration	NN
cord-257197-i9bucuma	298	58	method	method	NN
cord-257197-i9bucuma	298	59	in	in	IN
cord-257197-i9bucuma	298	60	cell	cell	NN
cord-257197-i9bucuma	298	61	culture	culture	NN
cord-257197-i9bucuma	298	62	alters	alter	VBZ
cord-257197-i9bucuma	298	63	particle	particle	NN
cord-257197-i9bucuma	298	64	-	-	HYPH
cord-257197-i9bucuma	298	65	cell	cell	NN
cord-257197-i9bucuma	298	66	interaction	interaction	NN
cord-257197-i9bucuma	298	67	Evaluating	evaluate	VBG
cord-257197-i9bucuma	298	68	the	the	DT
cord-257197-i9bucuma	298	69	effect	effect	NN
cord-257197-i9bucuma	298	70	of	of	IN
cord-257197-i9bucuma	298	71	assay	assay	NN
cord-257197-i9bucuma	298	72	preparation	preparation	NN
cord-257197-i9bucuma	298	73	on	on	IN
cord-257197-i9bucuma	298	74	the	the	DT
cord-257197-i9bucuma	298	75	uptake	uptake	NN
cord-257197-i9bucuma	298	76	of	of	IN
cord-257197-i9bucuma	298	77	gold	gold	NN
cord-257197-i9bucuma	298	78	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	298	79	by	by	IN
cord-257197-i9bucuma	298	80	RAW264.7	raw264.7	NN
cord-257197-i9bucuma	298	81	cells	cell	NNS
cord-257197-i9bucuma	298	82	Iron	iron	NN
cord-257197-i9bucuma	298	83	oxide	oxide	NN
cord-257197-i9bucuma	298	84	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	298	85	inhibit	inhibit	VBP
cord-257197-i9bucuma	298	86	tumour	tumour	NN
cord-257197-i9bucuma	298	87	growth	growth	NN
cord-257197-i9bucuma	298	88	by	by	IN
cord-257197-i9bucuma	298	89	inducing	induce	VBG
cord-257197-i9bucuma	298	90	pro	pro	JJ
cord-257197-i9bucuma	298	91	-	-	JJ
cord-257197-i9bucuma	298	92	inflammatory	inflammatory	JJ
cord-257197-i9bucuma	298	93	macrophage	macrophage	NN
cord-257197-i9bucuma	298	94	polarization	polarization	NN
cord-257197-i9bucuma	298	95	in	in	IN
cord-257197-i9bucuma	298	96	tumour	tumour	NN
cord-257197-i9bucuma	298	97	tissues	tissue	NNS
cord-257197-i9bucuma	299	1	Gold	gold	NN
cord-257197-i9bucuma	299	2	quantum	quantum	NN
cord-257197-i9bucuma	299	3	dots	dot	NNS
cord-257197-i9bucuma	299	4	impair	impair	VBP
cord-257197-i9bucuma	299	5	the	the	DT
cord-257197-i9bucuma	299	6	tumorigenic	tumorigenic	JJ
cord-257197-i9bucuma	299	7	potential	potential	NN
cord-257197-i9bucuma	299	8	of	of	IN
cord-257197-i9bucuma	299	9	glioma	glioma	NN
cord-257197-i9bucuma	299	10	stem	stem	NN
cord-257197-i9bucuma	299	11	-	-	HYPH
cord-257197-i9bucuma	299	12	like	like	JJ
cord-257197-i9bucuma	299	13	cells	cell	NNS
cord-257197-i9bucuma	299	14	via	via	IN
cord-257197-i9bucuma	299	15	beta	beta	NN
cord-257197-i9bucuma	299	16	-	-	HYPH
cord-257197-i9bucuma	299	17	catenin	catenin	NN
cord-257197-i9bucuma	299	18	downregulation	downregulation	NN
cord-257197-i9bucuma	299	19	in	in	IN
cord-257197-i9bucuma	299	20	vitro	vitro	FW
cord-257197-i9bucuma	300	1	It	-PRON-	PRP
cord-257197-i9bucuma	300	2	takes	take	VBZ
cord-257197-i9bucuma	300	3	more	more	JJR
cord-257197-i9bucuma	300	4	than	than	IN
cord-257197-i9bucuma	300	5	a	a	DT
cord-257197-i9bucuma	300	6	coating	coating	NN
cord-257197-i9bucuma	300	7	to	to	TO
cord-257197-i9bucuma	300	8	get	get	VB
cord-257197-i9bucuma	300	9	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	300	10	through	through	IN
cord-257197-i9bucuma	300	11	the	the	DT
cord-257197-i9bucuma	300	12	intestinal	intestinal	JJ
cord-257197-i9bucuma	300	13	barrier	barrier	NN
cord-257197-i9bucuma	300	14	in	in	IN
cord-257197-i9bucuma	300	15	vitro	vitro	FW
cord-257197-i9bucuma	300	16	Sandwich	Sandwich	NNP
cord-257197-i9bucuma	300	17	-	-	HYPH
cord-257197-i9bucuma	300	18	Cultured	cultured	JJ
cord-257197-i9bucuma	300	19	Hepatocytes	Hepatocytes	NNPS
cord-257197-i9bucuma	300	20	as	as	IN
cord-257197-i9bucuma	300	21	a	a	DT
cord-257197-i9bucuma	300	22	Tool	tool	NN
cord-257197-i9bucuma	300	23	to	to	TO
cord-257197-i9bucuma	300	24	Study	study	VB
cord-257197-i9bucuma	300	25	Drug	Drug	NNP
cord-257197-i9bucuma	300	26	Disposition	Disposition	NNP
cord-257197-i9bucuma	300	27	and	and	CC
cord-257197-i9bucuma	300	28	Drug	Drug	NNP
cord-257197-i9bucuma	300	29	-	-	HYPH
cord-257197-i9bucuma	300	30	Induced	Induced	NNP
cord-257197-i9bucuma	300	31	Liver	Liver	NNP
cord-257197-i9bucuma	300	32	Injury	injury	NN
cord-257197-i9bucuma	300	33	Is	be	VBZ
cord-257197-i9bucuma	300	34	it	-PRON-	PRP
cord-257197-i9bucuma	300	35	time	time	NN
cord-257197-i9bucuma	300	36	to	to	TO
cord-257197-i9bucuma	300	37	reinvent	reinvent	VB
cord-257197-i9bucuma	300	38	basic	basic	JJ
cord-257197-i9bucuma	300	39	cell	cell	NN
cord-257197-i9bucuma	300	40	culture	culture	NN
cord-257197-i9bucuma	300	41	medium	medium	NN
cord-257197-i9bucuma	300	42	?	?	.
cord-257197-i9bucuma	301	1	Protein	Protein	NNP
cord-257197-i9bucuma	301	2	Corona	Corona	NNP
cord-257197-i9bucuma	301	3	Composition	Composition	NNP
cord-257197-i9bucuma	301	4	of	of	IN
cord-257197-i9bucuma	301	5	Superparamagnetic	Superparamagnetic	NNP
cord-257197-i9bucuma	301	6	Iron	Iron	NNP
cord-257197-i9bucuma	301	7	Oxide	Oxide	NNP
cord-257197-i9bucuma	301	8	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	301	9	with	with	IN
cord-257197-i9bucuma	301	10	Various	Various	NNP
cord-257197-i9bucuma	301	11	Physico	Physico	NNP
cord-257197-i9bucuma	301	12	-	-	HYPH
cord-257197-i9bucuma	301	13	Chemical	Chemical	NNP
cord-257197-i9bucuma	301	14	Properties	Properties	NNPS
cord-257197-i9bucuma	301	15	and	and	CC
cord-257197-i9bucuma	301	16	Coatings	Coatings	NNPS
cord-257197-i9bucuma	301	17	Effect	Effect	NNP
cord-257197-i9bucuma	301	18	of	of	IN
cord-257197-i9bucuma	301	19	cell	cell	NN
cord-257197-i9bucuma	301	20	media	medium	NNS
cord-257197-i9bucuma	301	21	on	on	IN
cord-257197-i9bucuma	301	22	polymer	polymer	NN
cord-257197-i9bucuma	301	23	coated	coat	VBN
cord-257197-i9bucuma	301	24	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	301	25	iron	iron	NN
cord-257197-i9bucuma	301	26	oxide	oxide	NN
cord-257197-i9bucuma	301	27	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	301	28	(	(	-LRB-
cord-257197-i9bucuma	301	29	SPIONs	spion	NNS
cord-257197-i9bucuma	301	30	)	)	-RRB-
cord-257197-i9bucuma	301	31	:	:	:
cord-257197-i9bucuma	301	32	Colloidal	colloidal	JJ
cord-257197-i9bucuma	301	33	stability	stability	NN
cord-257197-i9bucuma	301	34	,	,	,
cord-257197-i9bucuma	301	35	cytotoxicity	cytotoxicity	NN
cord-257197-i9bucuma	301	36	,	,	,
cord-257197-i9bucuma	301	37	and	and	CC
cord-257197-i9bucuma	301	38	cellular	cellular	JJ
cord-257197-i9bucuma	301	39	uptake	uptake	NN
cord-257197-i9bucuma	301	40	studies	study	NNS
cord-257197-i9bucuma	302	1	How	how	WRB
cord-257197-i9bucuma	302	2	Entanglement	Entanglement	NNP
cord-257197-i9bucuma	302	3	of	of	IN
cord-257197-i9bucuma	302	4	Different	Different	NNP
cord-257197-i9bucuma	302	5	Physicochemical	Physicochemical	NNP
cord-257197-i9bucuma	302	6	Properties	Properties	NNP
cord-257197-i9bucuma	302	7	Complicates	complicate	VBZ
cord-257197-i9bucuma	302	8	the	the	DT
cord-257197-i9bucuma	302	9	Prediction	Prediction	NNP
cord-257197-i9bucuma	302	10	of	of	IN
cord-257197-i9bucuma	302	11	in	in	IN
cord-257197-i9bucuma	302	12	Vitro	Vitro	NNP
cord-257197-i9bucuma	302	13	and	and	CC
cord-257197-i9bucuma	302	14	in	in	IN
cord-257197-i9bucuma	302	15	Vivo	Vivo	NNP
cord-257197-i9bucuma	302	16	Interactions	Interactions	NNPS
cord-257197-i9bucuma	302	17	of	of	IN
cord-257197-i9bucuma	302	18	Gold	Gold	NNP
cord-257197-i9bucuma	302	19	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	303	1	Intracellular	Intracellular	NNP
cord-257197-i9bucuma	303	2	Accumulation	Accumulation	NNP
cord-257197-i9bucuma	303	3	of	of	IN
cord-257197-i9bucuma	303	4	Gold	Gold	NNP
cord-257197-i9bucuma	303	5	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	303	6	Leads	lead	VBZ
cord-257197-i9bucuma	303	7	to	to	IN
cord-257197-i9bucuma	303	8	Inhibition	Inhibition	NNP
cord-257197-i9bucuma	303	9	of	of	IN
cord-257197-i9bucuma	303	10	Macropinocytosis	Macropinocytosis	NNP
cord-257197-i9bucuma	303	11	to	to	TO
cord-257197-i9bucuma	303	12	Reduce	reduce	VB
cord-257197-i9bucuma	303	13	the	the	DT
cord-257197-i9bucuma	303	14	Endoplasmic	Endoplasmic	NNP
cord-257197-i9bucuma	303	15	Reticulum	Reticulum	NNP
cord-257197-i9bucuma	303	16	Stress	Stress	NNP
cord-257197-i9bucuma	303	17	Evaluation	Evaluation	NNP
cord-257197-i9bucuma	303	18	of	of	IN
cord-257197-i9bucuma	303	19	DNA	dna	NN
cord-257197-i9bucuma	303	20	interaction	interaction	NN
cord-257197-i9bucuma	303	21	,	,	,
cord-257197-i9bucuma	303	22	genotoxicity	genotoxicity	NN
cord-257197-i9bucuma	303	23	and	and	CC
cord-257197-i9bucuma	303	24	oxidative	oxidative	JJ
cord-257197-i9bucuma	303	25	stress	stress	NN
cord-257197-i9bucuma	303	26	induced	induce	VBN
cord-257197-i9bucuma	303	27	by	by	IN
cord-257197-i9bucuma	303	28	iron	iron	NN
cord-257197-i9bucuma	303	29	oxide	oxide	NN
cord-257197-i9bucuma	303	30	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	303	31	both	both	DT
cord-257197-i9bucuma	303	32	in	in	IN
cord-257197-i9bucuma	303	33	vitro	vitro	FW
cord-257197-i9bucuma	303	34	and	and	CC
cord-257197-i9bucuma	303	35	in	in	IN
cord-257197-i9bucuma	303	36	vivo	vivo	NN
cord-257197-i9bucuma	303	37	:	:	:
cord-257197-i9bucuma	304	1	attenuation	attenuation	NN
cord-257197-i9bucuma	304	2	by	by	IN
cord-257197-i9bucuma	304	3	thymoquinone	thymoquinone	NN
cord-257197-i9bucuma	304	4	Cytotoxicity	Cytotoxicity	NNP
cord-257197-i9bucuma	304	5	and	and	CC
cord-257197-i9bucuma	304	6	Cell	Cell	NNP
cord-257197-i9bucuma	304	7	Cycle	cycle	NN
cord-257197-i9bucuma	304	8	Effects	effect	NNS
cord-257197-i9bucuma	304	9	of	of	IN
cord-257197-i9bucuma	304	10	Bare	Bare	NNP
cord-257197-i9bucuma	304	11	and	and	CC
cord-257197-i9bucuma	304	12	Poly(vinyl	poly(vinyl	NN
cord-257197-i9bucuma	304	13	alcohol)-Coated	alcohol)-Coated	NNP
cord-257197-i9bucuma	304	14	Iron	Iron	NNP
cord-257197-i9bucuma	304	15	Oxide	Oxide	NNP
cord-257197-i9bucuma	304	16	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	304	17	in	in	IN
cord-257197-i9bucuma	304	18	Mouse	Mouse	NNP
cord-257197-i9bucuma	304	19	Fibroblasts	Fibroblasts	NNP
cord-257197-i9bucuma	304	20	Bare	Bare	NNP
cord-257197-i9bucuma	304	21	surface	surface	NN
cord-257197-i9bucuma	304	22	of	of	IN
cord-257197-i9bucuma	304	23	gold	gold	NN
cord-257197-i9bucuma	304	24	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	304	25	induces	induce	VBZ
cord-257197-i9bucuma	304	26	inflammation	inflammation	NN
cord-257197-i9bucuma	304	27	through	through	IN
cord-257197-i9bucuma	304	28	unfolding	unfold	VBG
cord-257197-i9bucuma	304	29	of	of	IN
cord-257197-i9bucuma	304	30	plasma	plasma	NN
cord-257197-i9bucuma	304	31	fibrinogen	fibrinogen	NN
cord-257197-i9bucuma	304	32	Functionalized	Functionalized	NNP
cord-257197-i9bucuma	304	33	gold	gold	NN
cord-257197-i9bucuma	304	34	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	304	35	for	for	IN
cord-257197-i9bucuma	304	36	topical	topical	JJ
cord-257197-i9bucuma	304	37	delivery	delivery	NN
cord-257197-i9bucuma	304	38	of	of	IN
cord-257197-i9bucuma	304	39	methotrexate	methotrexate	NNP
cord-257197-i9bucuma	304	40	for	for	IN
cord-257197-i9bucuma	304	41	the	the	DT
cord-257197-i9bucuma	304	42	possible	possible	JJ
cord-257197-i9bucuma	304	43	treatment	treatment	NN
cord-257197-i9bucuma	304	44	of	of	IN
cord-257197-i9bucuma	304	45	psoriasis	psoriasis	NN
cord-257197-i9bucuma	304	46	Endocytosis	Endocytosis	NNP
cord-257197-i9bucuma	304	47	of	of	IN
cord-257197-i9bucuma	304	48	nanomedicines	nanomedicines	NNP
cord-257197-i9bucuma	304	49	Physical	Physical	NNP
cord-257197-i9bucuma	304	50	Principles	Principles	NNPS
cord-257197-i9bucuma	304	51	of	of	IN
cord-257197-i9bucuma	304	52	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	304	53	Cellular	Cellular	NNP
cord-257197-i9bucuma	304	54	Endocytosis	Endocytosis	NNP
cord-257197-i9bucuma	304	55	Uptake	Uptake	NNP
cord-257197-i9bucuma	304	56	mechanisms	mechanism	NNS
cord-257197-i9bucuma	304	57	of	of	IN
cord-257197-i9bucuma	304	58	non	non	JJ
cord-257197-i9bucuma	304	59	-	-	JJ
cord-257197-i9bucuma	304	60	viral	viral	JJ
cord-257197-i9bucuma	304	61	gene	gene	NN
cord-257197-i9bucuma	304	62	delivery	delivery	NN
cord-257197-i9bucuma	304	63	Uptake	uptake	NN
cord-257197-i9bucuma	304	64	mechanism	mechanism	NN
cord-257197-i9bucuma	304	65	of	of	IN
cord-257197-i9bucuma	304	66	metabolic	metabolic	RB
cord-257197-i9bucuma	304	67	-	-	HYPH
cord-257197-i9bucuma	304	68	targeted	target	VBN
cord-257197-i9bucuma	304	69	gold	gold	NN
cord-257197-i9bucuma	304	70	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	304	71	Extraction	extraction	NN
cord-257197-i9bucuma	304	72	of	of	IN
cord-257197-i9bucuma	304	73	cholesterol	cholesterol	NN
cord-257197-i9bucuma	304	74	with	with	IN
cord-257197-i9bucuma	304	75	methyl	methyl	NN
cord-257197-i9bucuma	304	76	-	-	HYPH
cord-257197-i9bucuma	304	77	beta	beta	NN
cord-257197-i9bucuma	304	78	-	-	HYPH
cord-257197-i9bucuma	304	79	cyclodextrin	cyclodextrin	NN
cord-257197-i9bucuma	304	80	perturbs	perturb	VBZ
cord-257197-i9bucuma	304	81	formation	formation	NN
cord-257197-i9bucuma	304	82	of	of	IN
cord-257197-i9bucuma	304	83	clathrin	clathrin	NN
cord-257197-i9bucuma	304	84	-	-	HYPH
cord-257197-i9bucuma	304	85	coated	coat	VBN
cord-257197-i9bucuma	304	86	endocytic	endocytic	JJ
cord-257197-i9bucuma	304	87	vesicles	vesicle	NNS
cord-257197-i9bucuma	305	1	Dynasore	Dynasore	NNP
cord-257197-i9bucuma	305	2	-not	-not	:
cord-257197-i9bucuma	305	3	just	just	RB
cord-257197-i9bucuma	305	4	a	a	DT
cord-257197-i9bucuma	305	5	dynamin	dynamin	NN
cord-257197-i9bucuma	305	6	inhibitor	inhibitor	NN
cord-257197-i9bucuma	305	7	Caveolin-1	Caveolin-1	NNP
cord-257197-i9bucuma	305	8	and	and	CC
cord-257197-i9bucuma	305	9	CDC42	CDC42	NNP
cord-257197-i9bucuma	305	10	mediated	mediate	VBN
cord-257197-i9bucuma	305	11	endocytosis	endocytosis	NN
cord-257197-i9bucuma	305	12	of	of	IN
cord-257197-i9bucuma	305	13	silica	silica	NN
cord-257197-i9bucuma	305	14	-	-	HYPH
cord-257197-i9bucuma	305	15	coated	coat	VBN
cord-257197-i9bucuma	305	16	iron	iron	NN
cord-257197-i9bucuma	305	17	oxide	oxide	NN
cord-257197-i9bucuma	305	18	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	305	19	in	in	IN
cord-257197-i9bucuma	305	20	HeLa	HeLa	NNP
cord-257197-i9bucuma	305	21	cells	cell	NNS
cord-257197-i9bucuma	306	1	Increased	increase	VBN
cord-257197-i9bucuma	306	2	cellular	cellular	JJ
cord-257197-i9bucuma	306	3	uptake	uptake	NN
cord-257197-i9bucuma	306	4	of	of	IN
cord-257197-i9bucuma	306	5	peptide	peptide	NN
cord-257197-i9bucuma	306	6	-	-	HYPH
cord-257197-i9bucuma	306	7	modified	modify	VBN
cord-257197-i9bucuma	306	8	PEGylated	pegylated	JJ
cord-257197-i9bucuma	306	9	gold	gold	NN
cord-257197-i9bucuma	306	10	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	306	11	.	.	.
cord-257197-i9bucuma	307	1	Biochemical	biochemical	JJ
cord-257197-i9bucuma	307	2	and	and	CC
cord-257197-i9bucuma	307	3	Biophysical	Biophysical	NNP
cord-257197-i9bucuma	307	4	Research	Research	NNP
cord-257197-i9bucuma	307	5	Communications	Communications	NNPS
cord-257197-i9bucuma	307	6	Mechanisms	Mechanisms	NNP
cord-257197-i9bucuma	307	7	for	for	IN
cord-257197-i9bucuma	307	8	cellular	cellular	JJ
cord-257197-i9bucuma	307	9	uptake	uptake	NN
cord-257197-i9bucuma	307	10	of	of	IN
cord-257197-i9bucuma	307	11	nanosized	nanosized	JJ
cord-257197-i9bucuma	307	12	clinical	clinical	JJ
cord-257197-i9bucuma	307	13	MRI	MRI	NNP
cord-257197-i9bucuma	307	14	contrast	contrast	NN
cord-257197-i9bucuma	307	15	agents	agent	NNS
cord-257197-i9bucuma	307	16	Effects	effect	NNS
cord-257197-i9bucuma	307	17	of	of	IN
cord-257197-i9bucuma	307	18	Gold	gold	NN
cord-257197-i9bucuma	307	19	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	307	20	with	with	IN
cord-257197-i9bucuma	307	21	Different	different	JJ
cord-257197-i9bucuma	307	22	Surface	Surface	NNP
cord-257197-i9bucuma	307	23	Charges	charge	NNS
cord-257197-i9bucuma	307	24	on	on	IN
cord-257197-i9bucuma	307	25	Cellular	Cellular	NNP
cord-257197-i9bucuma	307	26	Internalization	Internalization	NNP
cord-257197-i9bucuma	307	27	and	and	CC
cord-257197-i9bucuma	307	28	Cytokine	Cytokine	NNP
cord-257197-i9bucuma	307	29	Responses	response	NNS
cord-257197-i9bucuma	307	30	in	in	IN
cord-257197-i9bucuma	307	31	Monocytes	Monocytes	NNPS
cord-257197-i9bucuma	307	32	Differential	differential	JJ
cord-257197-i9bucuma	307	33	internalization	internalization	NN
cord-257197-i9bucuma	307	34	of	of	IN
cord-257197-i9bucuma	307	35	brick	brick	NN
cord-257197-i9bucuma	307	36	shaped	shape	VBN
cord-257197-i9bucuma	307	37	iron	iron	NN
cord-257197-i9bucuma	307	38	oxide	oxide	NN
cord-257197-i9bucuma	307	39	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	307	40	by	by	IN
cord-257197-i9bucuma	307	41	endothelial	endothelial	JJ
cord-257197-i9bucuma	307	42	cells	cell	NNS
cord-257197-i9bucuma	307	43	Interactions	interaction	NNS
cord-257197-i9bucuma	307	44	at	at	IN
cord-257197-i9bucuma	307	45	the	the	DT
cord-257197-i9bucuma	307	46	cell	cell	NN
cord-257197-i9bucuma	307	47	membrane	membrane	NN
cord-257197-i9bucuma	307	48	and	and	CC
cord-257197-i9bucuma	307	49	pathways	pathway	NNS
cord-257197-i9bucuma	307	50	of	of	IN
cord-257197-i9bucuma	307	51	internalization	internalization	NN
cord-257197-i9bucuma	307	52	of	of	IN
cord-257197-i9bucuma	307	53	nano	nano	JJ
cord-257197-i9bucuma	307	54	-	-	HYPH
cord-257197-i9bucuma	307	55	sized	sized	JJ
cord-257197-i9bucuma	307	56	materials	material	NNS
cord-257197-i9bucuma	307	57	for	for	IN
cord-257197-i9bucuma	307	58	nanomedicine	nanomedicine	NN
cord-257197-i9bucuma	308	1	The	the	DT
cord-257197-i9bucuma	308	2	gene	gene	NN
cord-257197-i9bucuma	308	3	transfection	transfection	NN
cord-257197-i9bucuma	308	4	and	and	CC
cord-257197-i9bucuma	308	5	endocytic	endocytic	JJ
cord-257197-i9bucuma	308	6	uptake	uptake	NN
cord-257197-i9bucuma	308	7	pathways	pathway	NNS
cord-257197-i9bucuma	308	8	mediated	mediate	VBN
cord-257197-i9bucuma	308	9	by	by	IN
cord-257197-i9bucuma	308	10	PEGylated	pegylated	JJ
cord-257197-i9bucuma	308	11	PEI	PEI	NNP
cord-257197-i9bucuma	308	12	-	-	HYPH
cord-257197-i9bucuma	308	13	entrapped	entrap	VBN
cord-257197-i9bucuma	308	14	gold	gold	NN
cord-257197-i9bucuma	308	15	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	309	1	Folic	folic	JJ
cord-257197-i9bucuma	309	2	acid	acid	NN
cord-257197-i9bucuma	309	3	-	-	HYPH
cord-257197-i9bucuma	309	4	capped	cap	VBN
cord-257197-i9bucuma	309	5	PEGylated	pegylated	JJ
cord-257197-i9bucuma	309	6	magnetic	magnetic	JJ
cord-257197-i9bucuma	309	7	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	309	8	enter	enter	VBP
cord-257197-i9bucuma	309	9	cancer	cancer	NN
cord-257197-i9bucuma	309	10	cells	cell	NNS
cord-257197-i9bucuma	309	11	mostly	mostly	RB
cord-257197-i9bucuma	309	12	via	via	IN
cord-257197-i9bucuma	309	13	clathrin	clathrin	NN
cord-257197-i9bucuma	309	14	-	-	HYPH
cord-257197-i9bucuma	309	15	dependent	dependent	JJ
cord-257197-i9bucuma	309	16	endocytosis	endocytosis	NN
cord-257197-i9bucuma	309	17	Mechanisms	Mechanisms	NNPS
cord-257197-i9bucuma	309	18	of	of	IN
cord-257197-i9bucuma	309	19	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	309	20	-	-	HYPH
cord-257197-i9bucuma	309	21	Induced	Induced	NNP
cord-257197-i9bucuma	309	22	Oxidative	Oxidative	NNP
cord-257197-i9bucuma	309	23	Stress	Stress	NNP
cord-257197-i9bucuma	309	24	and	and	CC
cord-257197-i9bucuma	309	25	Toxicity	Toxicity	NNP
cord-257197-i9bucuma	309	26	Iron	iron	NN
cord-257197-i9bucuma	309	27	-	-	HYPH
cord-257197-i9bucuma	309	28	mediated	mediate	VBN
cord-257197-i9bucuma	309	29	lipid	lipid	NN
cord-257197-i9bucuma	309	30	peroxidation	peroxidation	NN
cord-257197-i9bucuma	309	31	and	and	CC
cord-257197-i9bucuma	309	32	lipid	lipid	NN
cord-257197-i9bucuma	309	33	raft	raft	NN
cord-257197-i9bucuma	309	34	disruption	disruption	NN
cord-257197-i9bucuma	309	35	in	in	IN
cord-257197-i9bucuma	309	36	low	low	JJ
cord-257197-i9bucuma	309	37	-	-	HYPH
cord-257197-i9bucuma	309	38	dose	dose	NN
cord-257197-i9bucuma	309	39	silica	silica	NN
cord-257197-i9bucuma	309	40	-	-	HYPH
cord-257197-i9bucuma	309	41	induced	induce	VBN
cord-257197-i9bucuma	309	42	macrophage	macrophage	NN
cord-257197-i9bucuma	309	43	cytokine	cytokine	NN
cord-257197-i9bucuma	309	44	production	production	NN
cord-257197-i9bucuma	309	45	.	.	.
cord-257197-i9bucuma	310	1	Free	Free	NNP
cord-257197-i9bucuma	310	2	Radical	Radical	NNP
cord-257197-i9bucuma	310	3	Biology	Biology	NNP
cord-257197-i9bucuma	310	4	and	and	CC
cord-257197-i9bucuma	310	5	Medicine	Medicine	NNP
cord-257197-i9bucuma	310	6	Gold	Gold	NNP
cord-257197-i9bucuma	310	7	Nanoparticles	Nanoparticles	NNPS
cord-257197-i9bucuma	310	8	as	as	IN
cord-257197-i9bucuma	310	9	a	a	DT
cord-257197-i9bucuma	310	10	Vaccine	Vaccine	NNP
cord-257197-i9bucuma	310	11	Platform	Platform	NNP
cord-257197-i9bucuma	310	12	:	:	:
cord-257197-i9bucuma	310	13	Influence	influence	NN
cord-257197-i9bucuma	310	14	of	of	IN
cord-257197-i9bucuma	310	15	Size	size	NN
cord-257197-i9bucuma	310	16	and	and	CC
cord-257197-i9bucuma	310	17	Shape	shape	NN
cord-257197-i9bucuma	310	18	on	on	IN
cord-257197-i9bucuma	310	19	Immunological	immunological	JJ
cord-257197-i9bucuma	310	20	Responses	response	NNS
cord-257197-i9bucuma	310	21	in	in	IN
cord-257197-i9bucuma	310	22	Vitro	Vitro	NNP
cord-257197-i9bucuma	310	23	and	and	CC
cord-257197-i9bucuma	310	24	in	in	IN
cord-257197-i9bucuma	310	25	Vivo	Vivo	NNP
cord-257197-i9bucuma	310	26	Gold	Gold	NNP
cord-257197-i9bucuma	310	27	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	310	28	as	as	IN
cord-257197-i9bucuma	310	29	an	an	DT
cord-257197-i9bucuma	310	30	adjuvant	adjuvant	NN
cord-257197-i9bucuma	310	31	:	:	:
cord-257197-i9bucuma	310	32	Influence	influence	NN
cord-257197-i9bucuma	310	33	of	of	IN
cord-257197-i9bucuma	310	34	size	size	NN
cord-257197-i9bucuma	310	35	,	,	,
cord-257197-i9bucuma	310	36	shape	shape	NN
cord-257197-i9bucuma	310	37	,	,	,
cord-257197-i9bucuma	310	38	and	and	CC
cord-257197-i9bucuma	310	39	technique	technique	NN
cord-257197-i9bucuma	310	40	of	of	IN
cord-257197-i9bucuma	310	41	combination	combination	NN
cord-257197-i9bucuma	310	42	with	with	IN
cord-257197-i9bucuma	310	43	CpG	CpG	NNP
cord-257197-i9bucuma	310	44	on	on	IN
cord-257197-i9bucuma	310	45	antibody	antibody	NN
cord-257197-i9bucuma	310	46	production	production	NN
cord-257197-i9bucuma	310	47	Iron	Iron	NNP
cord-257197-i9bucuma	310	48	Oxide	Oxide	NNP
cord-257197-i9bucuma	310	49	Nanoparticles	Nanoparticles	NNP
cord-257197-i9bucuma	310	50	-	-	HYPH
cord-257197-i9bucuma	310	51	Based	Based	NNP
cord-257197-i9bucuma	310	52	Vaccine	Vaccine	NNP
cord-257197-i9bucuma	310	53	Delivery	Delivery	NNP
cord-257197-i9bucuma	310	54	for	for	IN
cord-257197-i9bucuma	310	55	Cancer	Cancer	NNP
cord-257197-i9bucuma	310	56	Treatment	Treatment	NNP
cord-257197-i9bucuma	310	57	Physical	physical	JJ
cord-257197-i9bucuma	310	58	characterization	characterization	NN
cord-257197-i9bucuma	310	59	and	and	CC
cord-257197-i9bucuma	310	60	in	in	IN
cord-257197-i9bucuma	310	61	vivo	vivo	NN
cord-257197-i9bucuma	310	62	organ	organ	NN
cord-257197-i9bucuma	310	63	distribution	distribution	NN
cord-257197-i9bucuma	310	64	of	of	IN
cord-257197-i9bucuma	310	65	coated	coated	JJ
cord-257197-i9bucuma	310	66	iron	iron	NN
cord-257197-i9bucuma	310	67	oxide	oxide	NN
cord-257197-i9bucuma	310	68	nanoparticles	nanoparticle	VBZ
cord-257197-i9bucuma	310	69	Administration	Administration	NNP
cord-257197-i9bucuma	310	70	of	of	IN
cord-257197-i9bucuma	310	71	Substances	Substances	NNPS
cord-257197-i9bucuma	310	72	to	to	IN
cord-257197-i9bucuma	310	73	Laboratory	Laboratory	NNP
cord-257197-i9bucuma	310	74	Animals	animal	NNS
cord-257197-i9bucuma	310	75	:	:	:
cord-257197-i9bucuma	310	76	Routes	Routes	NNPS
cord-257197-i9bucuma	310	77	of	of	IN
cord-257197-i9bucuma	310	78	Administration	Administration	NNP
cord-257197-i9bucuma	310	79	and	and	CC
cord-257197-i9bucuma	310	80	Factors	Factors	NNPS
cord-257197-i9bucuma	310	81	to	to	TO
cord-257197-i9bucuma	310	82	Consider	consider	VB
cord-257197-i9bucuma	310	83	Routes	Routes	NNPS
cord-257197-i9bucuma	310	84	of	of	IN
cord-257197-i9bucuma	310	85	Administration	Administration	NNP
cord-257197-i9bucuma	310	86	Innate	Innate	NNP
cord-257197-i9bucuma	310	87	immune	immune	JJ
cord-257197-i9bucuma	310	88	response	response	NN
cord-257197-i9bucuma	310	89	in	in	IN
cord-257197-i9bucuma	310	90	Th1-and	th1-and	NN
cord-257197-i9bucuma	310	91	Th2-dominant	th2-dominant	JJ
cord-257197-i9bucuma	310	92	mouse	mouse	NN
cord-257197-i9bucuma	310	93	strains	strain	NNS
cord-257197-i9bucuma	310	94	Evaluating	evaluate	VBG
cord-257197-i9bucuma	310	95	the	the	DT
cord-257197-i9bucuma	310	96	potential	potential	NN
cord-257197-i9bucuma	310	97	of	of	IN
cord-257197-i9bucuma	310	98	gold	gold	NN
cord-257197-i9bucuma	310	99	,	,	,
cord-257197-i9bucuma	310	100	silver	silver	NN
cord-257197-i9bucuma	310	101	,	,	,
cord-257197-i9bucuma	310	102	and	and	CC
cord-257197-i9bucuma	310	103	silica	silica	NN
cord-257197-i9bucuma	310	104	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	310	105	to	to	TO
cord-257197-i9bucuma	310	106	saturate	saturate	VB
cord-257197-i9bucuma	310	107	mononuclear	mononuclear	JJ
cord-257197-i9bucuma	310	108	phagocytic	phagocytic	JJ
cord-257197-i9bucuma	310	109	system	system	NN
cord-257197-i9bucuma	310	110	tissues	tissue	NNS
cord-257197-i9bucuma	310	111	under	under	IN
cord-257197-i9bucuma	310	112	repeat	repeat	NN
cord-257197-i9bucuma	310	113	dosing	dosing	NN
cord-257197-i9bucuma	310	114	conditions	condition	NNS
cord-257197-i9bucuma	310	115	Effect	effect	NN
cord-257197-i9bucuma	310	116	of	of	IN
cord-257197-i9bucuma	310	117	surface	surface	NN
cord-257197-i9bucuma	310	118	-	-	HYPH
cord-257197-i9bucuma	310	119	modified	modify	VBN
cord-257197-i9bucuma	310	120	superparamagnetic	superparamagnetic	JJ
cord-257197-i9bucuma	310	121	iron	iron	NN
cord-257197-i9bucuma	310	122	oxide	oxide	NN
cord-257197-i9bucuma	310	123	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	310	124	(	(	-LRB-
cord-257197-i9bucuma	310	125	SPIONS	SPIONS	NNP
cord-257197-i9bucuma	310	126	)	)	-RRB-
cord-257197-i9bucuma	310	127	on	on	IN
cord-257197-i9bucuma	310	128	mast	mast	JJ
cord-257197-i9bucuma	310	129	cell	cell	NN
cord-257197-i9bucuma	310	130	infiltration	infiltration	NN
cord-257197-i9bucuma	310	131	:	:	:
cord-257197-i9bucuma	310	132	An	an	DT
cord-257197-i9bucuma	310	133	acute	acute	NN
cord-257197-i9bucuma	310	134	in	in	IN
cord-257197-i9bucuma	310	135	vivo	vivo	NN
cord-257197-i9bucuma	310	136	study	study	NN
cord-257197-i9bucuma	310	137	Effect	effect	NN
cord-257197-i9bucuma	310	138	of	of	IN
cord-257197-i9bucuma	310	139	removing	remove	VBG
cord-257197-i9bucuma	310	140	Kupffer	Kupffer	NNP
cord-257197-i9bucuma	310	141	cells	cell	NNS
cord-257197-i9bucuma	310	142	on	on	IN
cord-257197-i9bucuma	310	143	nanoparticle	nanoparticle	NN
cord-257197-i9bucuma	310	144	tumor	tumor	NN
cord-257197-i9bucuma	310	145	delivery	delivery	NN
cord-257197-i9bucuma	310	146	Biodistribution	Biodistribution	NNP
cord-257197-i9bucuma	310	147	,	,	,
cord-257197-i9bucuma	310	148	Clearance	Clearance	NNP
cord-257197-i9bucuma	310	149	And	and	CC
cord-257197-i9bucuma	310	150	Morphological	Morphological	NNP
cord-257197-i9bucuma	310	151	Alterations	alteration	NNS
cord-257197-i9bucuma	310	152	Of	of	IN
cord-257197-i9bucuma	310	153	Intravenously	intravenously	RB
cord-257197-i9bucuma	310	154	Administered	administer	VBN
cord-257197-i9bucuma	310	155	Iron	Iron	NNP
cord-257197-i9bucuma	310	156	Oxide	Oxide	NNP
cord-257197-i9bucuma	310	157	Nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	311	1	In	in	IN
cord-257197-i9bucuma	311	2	Male	Male	NNP
cord-257197-i9bucuma	311	3	Wistar	Wistar	NNP
cord-257197-i9bucuma	311	4	Rats	Rats	NNP
cord-257197-i9bucuma	311	5	PEG	peg	NN
cord-257197-i9bucuma	311	6	-	-	HYPH
cord-257197-i9bucuma	311	7	copolymer	copolymer	NN
cord-257197-i9bucuma	311	8	-	-	HYPH
cord-257197-i9bucuma	311	9	coated	coat	VBN
cord-257197-i9bucuma	311	10	iron	iron	NN
cord-257197-i9bucuma	311	11	oxide	oxide	NN
cord-257197-i9bucuma	311	12	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	311	13	that	that	WDT
cord-257197-i9bucuma	311	14	avoid	avoid	VBP
cord-257197-i9bucuma	311	15	the	the	DT
cord-257197-i9bucuma	311	16	reticuloendothelial	reticuloendothelial	JJ
cord-257197-i9bucuma	311	17	system	system	NN
cord-257197-i9bucuma	311	18	and	and	CC
cord-257197-i9bucuma	311	19	act	act	VB
cord-257197-i9bucuma	311	20	as	as	IN
cord-257197-i9bucuma	311	21	kidney	kidney	NN
cord-257197-i9bucuma	311	22	MRI	MRI	NNP
cord-257197-i9bucuma	311	23	contrast	contrast	NN
cord-257197-i9bucuma	311	24	agents	agent	NNS
cord-257197-i9bucuma	311	25	Biodegradable	biodegradable	JJ
cord-257197-i9bucuma	311	26	Gold	Gold	NNP
cord-257197-i9bucuma	311	27	Nanoclusters	Nanoclusters	NNP
cord-257197-i9bucuma	311	28	with	with	IN
cord-257197-i9bucuma	311	29	Improved	Improved	NNP
cord-257197-i9bucuma	311	30	Excretion	Excretion	NNP
cord-257197-i9bucuma	311	31	Due	due	IN
cord-257197-i9bucuma	311	32	to	to	IN
cord-257197-i9bucuma	311	33	pH	ph	NN
cord-257197-i9bucuma	311	34	-	-	HYPH
cord-257197-i9bucuma	311	35	Triggered	trigger	VBN
cord-257197-i9bucuma	311	36	Hydrophobic	Hydrophobic	NNP
cord-257197-i9bucuma	311	37	-	-	HYPH
cord-257197-i9bucuma	311	38	to	to	IN
cord-257197-i9bucuma	311	39	-	-	HYPH
cord-257197-i9bucuma	311	40	Hydrophilic	Hydrophilic	NNP
cord-257197-i9bucuma	311	41	Transition	Transition	NNP
cord-257197-i9bucuma	311	42	Effect	effect	NN
cord-257197-i9bucuma	311	43	of	of	IN
cord-257197-i9bucuma	311	44	Gold	Gold	NNP
cord-257197-i9bucuma	311	45	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	311	46	Size	Size	NNP
cord-257197-i9bucuma	311	47	on	on	IN
cord-257197-i9bucuma	311	48	Their	-PRON-	PRP$
cord-257197-i9bucuma	311	49	Properties	Properties	NNPS
cord-257197-i9bucuma	311	50	as	as	IN
cord-257197-i9bucuma	311	51	Contrast	Contrast	NNP
cord-257197-i9bucuma	311	52	Agents	agent	NNS
cord-257197-i9bucuma	311	53	for	for	IN
cord-257197-i9bucuma	311	54	Computed	Computed	NNP
cord-257197-i9bucuma	311	55	Tomography	Tomography	NNP
cord-257197-i9bucuma	311	56	Comparisons	comparison	NNS
cord-257197-i9bucuma	311	57	of	of	IN
cord-257197-i9bucuma	311	58	the	the	DT
cord-257197-i9bucuma	311	59	biodistribution	biodistribution	NN
cord-257197-i9bucuma	311	60	and	and	CC
cord-257197-i9bucuma	311	61	toxicological	toxicological	JJ
cord-257197-i9bucuma	311	62	examinations	examination	NNS
cord-257197-i9bucuma	311	63	after	after	IN
cord-257197-i9bucuma	311	64	repeated	repeat	VBN
cord-257197-i9bucuma	311	65	intravenous	intravenous	JJ
cord-257197-i9bucuma	311	66	administration	administration	NN
cord-257197-i9bucuma	311	67	of	of	IN
cord-257197-i9bucuma	311	68	silver	silver	NN
cord-257197-i9bucuma	311	69	and	and	CC
cord-257197-i9bucuma	311	70	gold	gold	NN
cord-257197-i9bucuma	311	71	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	311	72	in	in	IN
cord-257197-i9bucuma	311	73	mice	mouse	NNS
cord-257197-i9bucuma	311	74	Effects	effect	NNS
cord-257197-i9bucuma	311	75	of	of	IN
cord-257197-i9bucuma	311	76	core	core	NN
cord-257197-i9bucuma	311	77	size	size	NN
cord-257197-i9bucuma	311	78	and	and	CC
cord-257197-i9bucuma	311	79	PEG	peg	NN
cord-257197-i9bucuma	311	80	coating	coating	NN
cord-257197-i9bucuma	311	81	layer	layer	NN
cord-257197-i9bucuma	311	82	of	of	IN
cord-257197-i9bucuma	311	83	iron	iron	NN
cord-257197-i9bucuma	311	84	oxide	oxide	NN
cord-257197-i9bucuma	311	85	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	311	86	on	on	IN
cord-257197-i9bucuma	311	87	the	the	DT
cord-257197-i9bucuma	311	88	distribution	distribution	NN
cord-257197-i9bucuma	311	89	and	and	CC
cord-257197-i9bucuma	311	90	metabolism	metabolism	NN
cord-257197-i9bucuma	311	91	in	in	IN
cord-257197-i9bucuma	311	92	mice	mouse	NNS
cord-257197-i9bucuma	312	1	Intradermal	intradermal	JJ
cord-257197-i9bucuma	312	2	delivery	delivery	NN
cord-257197-i9bucuma	312	3	of	of	IN
cord-257197-i9bucuma	312	4	vaccine	vaccine	NN
cord-257197-i9bucuma	312	5	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	312	6	using	use	VBG
cord-257197-i9bucuma	312	7	hollow	hollow	JJ
cord-257197-i9bucuma	312	8	microneedle	microneedle	NN
cord-257197-i9bucuma	312	9	array	array	NN
cord-257197-i9bucuma	312	10	generates	generate	VBZ
cord-257197-i9bucuma	312	11	enhanced	enhance	VBN
cord-257197-i9bucuma	312	12	and	and	CC
cord-257197-i9bucuma	312	13	balanced	balanced	JJ
cord-257197-i9bucuma	312	14	immune	immune	JJ
cord-257197-i9bucuma	312	15	response	response	NN
cord-257197-i9bucuma	312	16	Conjugation	conjugation	NN
cord-257197-i9bucuma	312	17	of	of	IN
cord-257197-i9bucuma	312	18	a	a	DT
cord-257197-i9bucuma	312	19	peptide	peptide	JJ
cord-257197-i9bucuma	312	20	autoantigen	autoantigen	NN
cord-257197-i9bucuma	312	21	to	to	IN
cord-257197-i9bucuma	312	22	gold	gold	NN
cord-257197-i9bucuma	312	23	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	312	24	for	for	IN
cord-257197-i9bucuma	312	25	intradermally	intradermally	RB
cord-257197-i9bucuma	312	26	administered	administer	VBN
cord-257197-i9bucuma	312	27	antigen	antigen	NN
cord-257197-i9bucuma	312	28	specific	specific	JJ
cord-257197-i9bucuma	312	29	immunotherapy	immunotherapy	NN
cord-257197-i9bucuma	313	1	The	the	DT
cord-257197-i9bucuma	313	2	toxicity	toxicity	NN
cord-257197-i9bucuma	313	3	and	and	CC
cord-257197-i9bucuma	313	4	distribution	distribution	NN
cord-257197-i9bucuma	313	5	of	of	IN
cord-257197-i9bucuma	313	6	iron	iron	NN
cord-257197-i9bucuma	313	7	oxide	oxide	NN
cord-257197-i9bucuma	313	8	-	-	HYPH
cord-257197-i9bucuma	313	9	zinc	zinc	NN
cord-257197-i9bucuma	313	10	oxide	oxide	NN
cord-257197-i9bucuma	313	11	core	core	NN
cord-257197-i9bucuma	313	12	-	-	HYPH
cord-257197-i9bucuma	313	13	shell	shell	NN
cord-257197-i9bucuma	313	14	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	313	15	in	in	IN
cord-257197-i9bucuma	313	16	C57BL/6	C57BL/6	NNP
cord-257197-i9bucuma	313	17	mice	mouse	NNS
cord-257197-i9bucuma	313	18	after	after	IN
cord-257197-i9bucuma	313	19	repeated	repeat	VBD
cord-257197-i9bucuma	313	20	subcutaneous	subcutaneous	JJ
cord-257197-i9bucuma	313	21	administration	administration	NN
cord-257197-i9bucuma	313	22	Accumulation	Accumulation	NNP
cord-257197-i9bucuma	313	23	of	of	IN
cord-257197-i9bucuma	313	24	biosynthesized	biosynthesized	NNP
cord-257197-i9bucuma	313	25	gold	gold	NN
cord-257197-i9bucuma	313	26	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	313	27	and	and	CC
cord-257197-i9bucuma	313	28	its	-PRON-	PRP$
cord-257197-i9bucuma	313	29	impact	impact	NN
cord-257197-i9bucuma	313	30	on	on	IN
cord-257197-i9bucuma	313	31	various	various	JJ
cord-257197-i9bucuma	313	32	organs	organ	NNS
cord-257197-i9bucuma	313	33	of	of	IN
cord-257197-i9bucuma	313	34	Sprague	Sprague	NNP
cord-257197-i9bucuma	313	35	Dawley	Dawley	NNP
cord-257197-i9bucuma	313	36	rats	rat	NNS
cord-257197-i9bucuma	313	37	:	:	:
cord-257197-i9bucuma	313	38	a	a	DT
cord-257197-i9bucuma	313	39	systematic	systematic	JJ
cord-257197-i9bucuma	313	40	study	study	NN
cord-257197-i9bucuma	313	41	Nanoparticle	Nanoparticle	NNP
cord-257197-i9bucuma	313	42	-	-	HYPH
cord-257197-i9bucuma	313	43	based	base	VBN
cord-257197-i9bucuma	313	44	vaccines	vaccine	NNS
cord-257197-i9bucuma	313	45	:	:	:
cord-257197-i9bucuma	313	46	opportunities	opportunity	NNS
cord-257197-i9bucuma	313	47	and	and	CC
cord-257197-i9bucuma	313	48	limitations	limitation	NNS
cord-257197-i9bucuma	313	49	The	the	DT
cord-257197-i9bucuma	313	50	Physiological	physiological	JJ
cord-257197-i9bucuma	313	51	Sources	Sources	NNPS
cord-257197-i9bucuma	313	52	of	of	IN
cord-257197-i9bucuma	313	53	,	,	,
cord-257197-i9bucuma	313	54	Clinical	clinical	JJ
cord-257197-i9bucuma	313	55	Significance	significance	NN
cord-257197-i9bucuma	313	56	of	of	IN
cord-257197-i9bucuma	313	57	,	,	,
cord-257197-i9bucuma	313	58	and	and	CC
cord-257197-i9bucuma	313	59	Laboratory	Laboratory	NNP
cord-257197-i9bucuma	313	60	-	-	HYPH
cord-257197-i9bucuma	313	61	Testing	Testing	NNP
cord-257197-i9bucuma	313	62	Methods	method	NNS
cord-257197-i9bucuma	313	63	for	for	IN
cord-257197-i9bucuma	313	64	Determining	determine	VBG
cord-257197-i9bucuma	313	65	Enzyme	Enzyme	NNP
cord-257197-i9bucuma	313	66	Levels	Levels	NNP
cord-257197-i9bucuma	313	67	.	.	.
cord-257197-i9bucuma	314	1	Labmedicine	Labmedicine	NNP
cord-257197-i9bucuma	314	2	Size	Size	NNP
cord-257197-i9bucuma	314	3	-	-	HYPH
cord-257197-i9bucuma	314	4	and	and	CC
cord-257197-i9bucuma	314	5	cell	cell	NN
cord-257197-i9bucuma	314	6	type	type	NN
cord-257197-i9bucuma	314	7	-	-	HYPH
cord-257197-i9bucuma	314	8	dependent	dependent	JJ
cord-257197-i9bucuma	314	9	cellular	cellular	JJ
cord-257197-i9bucuma	314	10	uptake	uptake	NN
cord-257197-i9bucuma	314	11	,	,	,
cord-257197-i9bucuma	314	12	cytotoxicity	cytotoxicity	NN
cord-257197-i9bucuma	314	13	and	and	CC
cord-257197-i9bucuma	314	14	in	in	IN
cord-257197-i9bucuma	314	15	vivo	vivo	NN
cord-257197-i9bucuma	314	16	distribution	distribution	NN
cord-257197-i9bucuma	314	17	of	of	IN
cord-257197-i9bucuma	314	18	gold	gold	NN
cord-257197-i9bucuma	314	19	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	314	20	Biodistribution	Biodistribution	NNP
cord-257197-i9bucuma	314	21	,	,	,
cord-257197-i9bucuma	314	22	pharmacokinetics	pharmacokinetic	NNS
cord-257197-i9bucuma	314	23	,	,	,
cord-257197-i9bucuma	314	24	and	and	CC
cord-257197-i9bucuma	314	25	toxicity	toxicity	NN
cord-257197-i9bucuma	314	26	of	of	IN
cord-257197-i9bucuma	314	27	dendrimer	dendrimer	NNP
cord-257197-i9bucuma	314	28	-	-	HYPH
cord-257197-i9bucuma	314	29	coated	coat	VBN
cord-257197-i9bucuma	314	30	iron	iron	NN
cord-257197-i9bucuma	314	31	oxide	oxide	NN
cord-257197-i9bucuma	314	32	nanoparticles	nanoparticle	NNS
cord-257197-i9bucuma	314	33	in	in	IN
cord-257197-i9bucuma	314	34	BALB	BALB	NNP
cord-257197-i9bucuma	314	35	/	/	SYM
cord-257197-i9bucuma	314	36	c	c	NN
cord-257197-i9bucuma	314	37	mice	mouse	NNS
cord-257197-i9bucuma	315	1	This	this	DT
cord-257197-i9bucuma	315	2	manuscript	manuscript	NN
cord-257197-i9bucuma	315	3	is	be	VBZ
cord-257197-i9bucuma	315	4	contribution	contribution	NN
cord-257197-i9bucuma	315	5	number	number	NN
cord-257197-i9bucuma	315	6	20	20	CD
cord-257197-i9bucuma	315	7	-	-	SYM
cord-257197-i9bucuma	315	8	333-J	333-j	CD
cord-257197-i9bucuma	315	9	from	from	IN
cord-257197-i9bucuma	315	10	the	the	DT
cord-257197-i9bucuma	315	11	Kansas	Kansas	NNP
cord-257197-i9bucuma	315	12	Agricultural	Agricultural	NNP
cord-257197-i9bucuma	315	13	Experiment	Experiment	NNP
cord-257197-i9bucuma	315	14	 	 	_SP