id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012891-heqsfzkm	Blanco Vázquez, Cristina	Detection of latent forms of Mycobacterium avium subsp. paratuberculosis infection using host biomarker-based ELISAs greatly improves paratuberculosis diagnostic sensitivity	2020-09-03		.txt	text/plain	7818	354	43	The aim of this study was to evaluate the diagnostic potential of commercial ELISAs based on detection of these five bovine biomarkers to detect latent and patent forms of MAP infection in naturally infected cattle, using reference serum samples from well characterized animals with focal, multifocal and diffuse histological lesions in their intestinal or associated lymphoid tissues [40]. The diagnostic performance of the ABCA13, MMP8 and SPARC-based ELISAs for the focal and any type of lesion groups was compared with the IDEXX ELISA and additionally with other conventional PTB diagnosis methods such as specific fecal and tissue real-time PCR and bacteriological culture ( Table 4 ). Our results indicate that the ABCA13, SPARC and MMP8-based ELISAs have higher AUC values and sensitivities than the IDEXX ELISA and other current diagnostic methods for detection of animals with focal, multifocal and any type of histopathological lesions, respectively.	./cache/cord-012891-heqsfzkm.txt	./txt/cord-012891-heqsfzkm.txt