id author title date pages extension mime words sentences flesch summary cache txt cord-026559-xx52u01h Tripathi, Siddhartha Blood Plasma Microfluidic Device: Aiming for the Detection of COVID-19 Antibodies Using an On-Chip ELISA Platform 2020-06-10 .txt text/plain 2010 125 52 title: Blood Plasma Microfluidic Device: Aiming for the Detection of COVID-19 Antibodies Using an On-Chip ELISA Platform We propose to first separate plasma from whole human blood using a microfluidic device and subsequently perform the detection of antibodies in the separated plasma using a semi-automated on-chip ELISA. The reported plasma separation microdevice is not only an alternate to the centrifuge, but it can also be easily integrated with a biosensing platform/detection technology (for example, ELISA) and result in a point-of-care device. (2020) have reported successful detection of SARS-CoV-2 virus with high sensitivity in swab specimens Fig. 1 a Blood plasma microdevice design and zoomed view at the junction. Herein, we propose the integration of sandwich ELISA (enzyme-linked immunoabsorbent assay) with the blood plasma separation microdevice to detect COVID-19 antibodies after minor modifications in the design. b Experi-mental sandwich ELISA: showing steps to identify the presence of SARS-CoV-2 (COVID-19) antibodies present in blood plasma separated and flows towards the plasma outlet reservoir. ./cache/cord-026559-xx52u01h.txt ./txt/cord-026559-xx52u01h.txt