id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277735-a9gkath5	Leung, Danny Tze Ming	Antibody Response of Patients with Severe Acute Respiratory Syndrome (SARS) Targets the Viral Nucleocapsid	2004-07-15		.txt	text/plain	4010	192	55	We examined serum samples obtained from 46 patients with SARS, 40 patients with non-SARS pneumonia, and 38 healthy individuals, by use of Western blotting (WB), enzyme-linked immunoassay (ELISA), and immunofluorescence assay, using both native and bacterially produced antigens of the virus. Both the humoral and cellular arms of the adaptive immune response are presumed to be important in controlling 2 or preparation U reacted with a serum sample from a patient with SARS showing the highly reactive antigens-nucleocapsid (N) 1, N2, and N3-in the former. Second, we made a recombinant antigen of the N-terminal half of the N protein (rNa), and, when it was used in an IgG ELISA, we found results almost identical to those found with the crude viral extract (89% sensitivity and 94%-95% specificity), including 4 negative cases in common ( figure 2) .	./cache/cord-277735-a9gkath5.txt	./txt/cord-277735-a9gkath5.txt