id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-016640-pvlg3nkp	Baron, Ellen Jo	Technical and Clinical Niches for Point of Care Molecular Devices	2012-04-05		.txt	text/plain	2868	140	46	POCT infectious disease molecular assays may be developed to detect speci fi c • infections for which a rapid response is desirable. The most widely used molecular test at patient POC sites is the real-time PCR (RT-PCR) assay for detection of nasal colonization of methicillin-resistant Staphylococcus aureus (MRSA) [ 2 ] . Another rapid molecular test has been FDA-cleared for multiplex detection of 15 respiratory viruses, including adenovirus, 2 coronavirus strains, 5 in fl uenza strains, human metapneumovirus, parain fl uenza virus types 1-4, RSV, and rhino-enterovirus, with a time-to-result of 1-1.5 h using a novel multiplex PCR and array detection format [ 14 ] . Although other PCR methods for virus detection and identi fi cation in respiratory secretions are available and show excellent sensitivities and speci fi cities, they are not candidates for POC tests due to their complexity, long performance time, or format that leads to inef fi ciencies when performing non-batch (such as stat) testing [ 14 ] .	./cache/cord-016640-pvlg3nkp.txt	./txt/cord-016640-pvlg3nkp.txt