id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-274061-ynqxgyw6	Epstein, Jay S.	Blood system changes since recognition of transfusion‐associated AIDS	2013-10-17		.txt	text/plain	6253	268	42	In a set of 14 recommendations directed primarily at federal agencies, the IOM called for a more responsive and integrated decision-making process including establishment of a Blood Safety Council reporting to a designated Blood Safety Director within HHS and a standing "expert panel" to assure communication of blood product risks and alternatives to their use both to care providers and to the public. Several possible strategies were presented, including deferral of blood donations by persons known to be at increased risk for AIDS and the use of surrogate tests to identify persons at increased risk of transmission, such as those with detectable antibody to hepatitis B core antigen (anti-HBc) or low CD4/CD8 T-cell ratios. The Transfusion Transmitted Virus Study, supported by the National Heart, Lung and Blood Institute, published a retrospective analysis of a prospective study that showed that alanine aminotransferase (ALT) testing of donors might effect a 30% reduction in TAH incidence.	./cache/cord-274061-ynqxgyw6.txt	./txt/cord-274061-ynqxgyw6.txt