id sid tid token lemma pos cord-280571-ntgt5hy9 1 1 key key JJ cord-280571-ntgt5hy9 1 2 : : : cord-280571-ntgt5hy9 1 3 cord-280571-ntgt5hy9 cord-280571-ntgt5hy9 JJ cord-280571-ntgt5hy9 1 4 authors author NNS cord-280571-ntgt5hy9 1 5 : : : cord-280571-ntgt5hy9 1 6 Ginocchio Ginocchio NNP cord-280571-ntgt5hy9 1 7 , , , cord-280571-ntgt5hy9 1 8 Christine Christine NNP cord-280571-ntgt5hy9 1 9 C. C. NNP cord-280571-ntgt5hy9 1 10 title title NN cord-280571-ntgt5hy9 1 11 : : : cord-280571-ntgt5hy9 1 12 Strengths Strengths NNP cord-280571-ntgt5hy9 1 13 and and CC cord-280571-ntgt5hy9 1 14 Weaknesses weakness NNS cord-280571-ntgt5hy9 1 15 of of IN cord-280571-ntgt5hy9 1 16 FDA FDA NNP cord-280571-ntgt5hy9 1 17 - - HYPH cord-280571-ntgt5hy9 1 18 Approved Approved NNP cord-280571-ntgt5hy9 1 19 / / SYM cord-280571-ntgt5hy9 1 20 Cleared Cleared NNP cord-280571-ntgt5hy9 1 21 Diagnostic Diagnostic NNP cord-280571-ntgt5hy9 1 22 Devices Devices NNPS cord-280571-ntgt5hy9 1 23 for for IN cord-280571-ntgt5hy9 1 24 the the DT cord-280571-ntgt5hy9 1 25 Molecular Molecular NNP cord-280571-ntgt5hy9 1 26 Detection Detection NNP cord-280571-ntgt5hy9 1 27 of of IN cord-280571-ntgt5hy9 1 28 Respiratory respiratory JJ cord-280571-ntgt5hy9 1 29 Pathogens Pathogens NNPS cord-280571-ntgt5hy9 1 30 date date NN cord-280571-ntgt5hy9 1 31 : : : cord-280571-ntgt5hy9 1 32 2011 2011 CD cord-280571-ntgt5hy9 1 33 - - SYM cord-280571-ntgt5hy9 1 34 05 05 CD cord-280571-ntgt5hy9 1 35 - - HYPH cord-280571-ntgt5hy9 1 36 01 01 CD cord-280571-ntgt5hy9 1 37 journal journal NN cord-280571-ntgt5hy9 1 38 : : : cord-280571-ntgt5hy9 2 1 Clin Clin NNP cord-280571-ntgt5hy9 2 2 Infect infect VB cord-280571-ntgt5hy9 2 3 Dis Dis NNP cord-280571-ntgt5hy9 2 4 DOI doi NN cord-280571-ntgt5hy9 2 5 : : : cord-280571-ntgt5hy9 3 1 10.1093 10.1093 CD cord-280571-ntgt5hy9 3 2 / / SYM cord-280571-ntgt5hy9 3 3 cid cid NN cord-280571-ntgt5hy9 3 4 / / SYM cord-280571-ntgt5hy9 3 5 cir046 cir046 NNP cord-280571-ntgt5hy9 4 1 sha sha NNP cord-280571-ntgt5hy9 4 2 : : : cord-280571-ntgt5hy9 5 1 92e0bd5025723bb086615c9c3729ba100ac8e4a4 92e0bd5025723bb086615c9c3729ba100ac8e4a4 CD cord-280571-ntgt5hy9 6 1 doc_id doc_id CD cord-280571-ntgt5hy9 6 2 : : : cord-280571-ntgt5hy9 7 1 280571 280571 CD cord-280571-ntgt5hy9 7 2 cord_uid cord_uid NNS cord-280571-ntgt5hy9 7 3 : : : cord-280571-ntgt5hy9 7 4 ntgt5hy9 ntgt5hy9 ADD cord-280571-ntgt5hy9 8 1 The the DT cord-280571-ntgt5hy9 8 2 rapid rapid JJ cord-280571-ntgt5hy9 8 3 , , , cord-280571-ntgt5hy9 8 4 sensitive sensitive JJ cord-280571-ntgt5hy9 8 5 , , , cord-280571-ntgt5hy9 8 6 and and CC cord-280571-ntgt5hy9 8 7 specific specific JJ cord-280571-ntgt5hy9 8 8 identification identification NN cord-280571-ntgt5hy9 8 9 of of IN cord-280571-ntgt5hy9 8 10 the the DT cord-280571-ntgt5hy9 8 11 microbial microbial JJ cord-280571-ntgt5hy9 8 12 etiological etiological JJ cord-280571-ntgt5hy9 8 13 characteristics characteristic NNS cord-280571-ntgt5hy9 8 14 of of IN cord-280571-ntgt5hy9 8 15 respiratory respiratory JJ cord-280571-ntgt5hy9 8 16 tract tract NN cord-280571-ntgt5hy9 8 17 infections infection NNS cord-280571-ntgt5hy9 8 18 enhances enhance VBZ cord-280571-ntgt5hy9 8 19 the the DT cord-280571-ntgt5hy9 8 20 appropriate appropriate JJ cord-280571-ntgt5hy9 8 21 use use NN cord-280571-ntgt5hy9 8 22 of of IN cord-280571-ntgt5hy9 8 23 both both DT cord-280571-ntgt5hy9 8 24 antibiotics antibiotic NNS cord-280571-ntgt5hy9 8 25 and and CC cord-280571-ntgt5hy9 8 26 antiviral antiviral JJ cord-280571-ntgt5hy9 8 27 agents agent NNS cord-280571-ntgt5hy9 8 28 and and CC cord-280571-ntgt5hy9 8 29 reduces reduce VBZ cord-280571-ntgt5hy9 8 30 the the DT cord-280571-ntgt5hy9 8 31 risk risk NN cord-280571-ntgt5hy9 8 32 of of IN cord-280571-ntgt5hy9 8 33 nosocomial nosocomial JJ cord-280571-ntgt5hy9 8 34 transmission transmission NN cord-280571-ntgt5hy9 8 35 . . . cord-280571-ntgt5hy9 9 1 This this DT cord-280571-ntgt5hy9 9 2 article article NN cord-280571-ntgt5hy9 9 3 reviews review VBZ cord-280571-ntgt5hy9 9 4 the the DT cord-280571-ntgt5hy9 9 5 current current JJ cord-280571-ntgt5hy9 9 6 nucleic nucleic JJ cord-280571-ntgt5hy9 9 7 acid acid NN cord-280571-ntgt5hy9 9 8 amplification amplification NN cord-280571-ntgt5hy9 9 9 tests test NNS cord-280571-ntgt5hy9 9 10 approved approve VBN cord-280571-ntgt5hy9 9 11 by by IN cord-280571-ntgt5hy9 9 12 the the DT cord-280571-ntgt5hy9 9 13 U.S. U.S. NNP cord-280571-ntgt5hy9 9 14 Food Food NNP cord-280571-ntgt5hy9 9 15 and and CC cord-280571-ntgt5hy9 9 16 Drug Drug NNP cord-280571-ntgt5hy9 9 17 Administration Administration NNP cord-280571-ntgt5hy9 9 18 ( ( -LRB- cord-280571-ntgt5hy9 9 19 FDA FDA NNP cord-280571-ntgt5hy9 9 20 ) ) -RRB- cord-280571-ntgt5hy9 9 21 for for IN cord-280571-ntgt5hy9 9 22 the the DT cord-280571-ntgt5hy9 9 23 detection detection NN cord-280571-ntgt5hy9 9 24 of of IN cord-280571-ntgt5hy9 9 25 respiratory respiratory JJ cord-280571-ntgt5hy9 9 26 pathogens pathogen NNS cord-280571-ntgt5hy9 9 27 . . . cord-280571-ntgt5hy9 10 1 In in IN cord-280571-ntgt5hy9 10 2 addition addition NN cord-280571-ntgt5hy9 10 3 , , , cord-280571-ntgt5hy9 10 4 Emergency Emergency NNP cord-280571-ntgt5hy9 10 5 Use Use NNP cord-280571-ntgt5hy9 10 6 Authorization Authorization NNP cord-280571-ntgt5hy9 10 7 tests test NNS cord-280571-ntgt5hy9 10 8 for for IN cord-280571-ntgt5hy9 10 9 the the DT cord-280571-ntgt5hy9 10 10 detection detection NN cord-280571-ntgt5hy9 10 11 of of IN cord-280571-ntgt5hy9 10 12 2009 2009 CD cord-280571-ntgt5hy9 10 13 influenza influenza NN cord-280571-ntgt5hy9 10 14 A a DT cord-280571-ntgt5hy9 10 15 H1N1 H1N1 NNP cord-280571-ntgt5hy9 10 16 are be VBP cord-280571-ntgt5hy9 10 17 discussed discuss VBN cord-280571-ntgt5hy9 10 18 . . . cord-280571-ntgt5hy9 11 1 The the DT cord-280571-ntgt5hy9 11 2 advantages advantage NNS cord-280571-ntgt5hy9 11 3 and and CC cord-280571-ntgt5hy9 11 4 limitations limitation NNS cord-280571-ntgt5hy9 11 5 of of IN cord-280571-ntgt5hy9 11 6 the the DT cord-280571-ntgt5hy9 11 7 current current JJ cord-280571-ntgt5hy9 11 8 FDA FDA NNP cord-280571-ntgt5hy9 11 9 - - HYPH cord-280571-ntgt5hy9 11 10 approved approve VBN cord-280571-ntgt5hy9 11 11 / / SYM cord-280571-ntgt5hy9 11 12 cleared clear VBN cord-280571-ntgt5hy9 11 13 tests test NNS cord-280571-ntgt5hy9 11 14 are be VBP cord-280571-ntgt5hy9 11 15 reviewed review VBN cord-280571-ntgt5hy9 11 16 . . . cord-280571-ntgt5hy9 12 1 The the DT cord-280571-ntgt5hy9 12 2 identification identification NN cord-280571-ntgt5hy9 12 3 of of IN cord-280571-ntgt5hy9 12 4 the the DT cord-280571-ntgt5hy9 12 5 causative causative JJ cord-280571-ntgt5hy9 12 6 agent(s agent(s NNP cord-280571-ntgt5hy9 12 7 ) ) -RRB- cord-280571-ntgt5hy9 12 8 of of IN cord-280571-ntgt5hy9 12 9 respiratory respiratory JJ cord-280571-ntgt5hy9 12 10 tract tract NN cord-280571-ntgt5hy9 12 11 infections infection NNS cord-280571-ntgt5hy9 12 12 is be VBZ cord-280571-ntgt5hy9 12 13 essential essential JJ cord-280571-ntgt5hy9 12 14 to to TO cord-280571-ntgt5hy9 12 15 provide provide VB cord-280571-ntgt5hy9 12 16 an an DT cord-280571-ntgt5hy9 12 17 accurate accurate JJ cord-280571-ntgt5hy9 12 18 diagnosis diagnosis NN cord-280571-ntgt5hy9 12 19 , , , cord-280571-ntgt5hy9 12 20 appropriately appropriately RB cord-280571-ntgt5hy9 12 21 manage manage VB cord-280571-ntgt5hy9 12 22 patient patient JJ cord-280571-ntgt5hy9 12 23 care care NN cord-280571-ntgt5hy9 12 24 , , , cord-280571-ntgt5hy9 12 25 and and CC cord-280571-ntgt5hy9 12 26 reduce reduce VB cord-280571-ntgt5hy9 12 27 the the DT cord-280571-ntgt5hy9 12 28 risk risk NN cord-280571-ntgt5hy9 12 29 of of IN cord-280571-ntgt5hy9 12 30 nosocomial nosocomial JJ cord-280571-ntgt5hy9 12 31 transmission transmission NN cord-280571-ntgt5hy9 12 32 within within IN cord-280571-ntgt5hy9 12 33 health health NN cord-280571-ntgt5hy9 12 34 care care NN cord-280571-ntgt5hy9 12 35 facilities facility NNS cord-280571-ntgt5hy9 12 36 . . . cord-280571-ntgt5hy9 13 1 With with IN cord-280571-ntgt5hy9 13 2 the the DT cord-280571-ntgt5hy9 13 3 steady steady JJ cord-280571-ntgt5hy9 13 4 rise rise NN cord-280571-ntgt5hy9 13 5 of of IN cord-280571-ntgt5hy9 13 6 antibiotic antibiotic JJ cord-280571-ntgt5hy9 13 7 resistance resistance NN cord-280571-ntgt5hy9 13 8 and and CC cord-280571-ntgt5hy9 13 9 limited limited JJ cord-280571-ntgt5hy9 13 10 or or CC cord-280571-ntgt5hy9 13 11 no no DT cord-280571-ntgt5hy9 13 12 options option NNS cord-280571-ntgt5hy9 13 13 available available JJ cord-280571-ntgt5hy9 13 14 for for IN cord-280571-ntgt5hy9 13 15 the the DT cord-280571-ntgt5hy9 13 16 treatment treatment NN cord-280571-ntgt5hy9 13 17 of of IN cord-280571-ntgt5hy9 13 18 multidrug multidrug NN cord-280571-ntgt5hy9 13 19 or or CC cord-280571-ntgt5hy9 13 20 panresistant panresistant JJ cord-280571-ntgt5hy9 13 21 bacterial bacterial JJ cord-280571-ntgt5hy9 13 22 infections infection NNS cord-280571-ntgt5hy9 13 23 , , , cord-280571-ntgt5hy9 13 24 pathogen pathogen NN cord-280571-ntgt5hy9 13 25 identification identification NN cord-280571-ntgt5hy9 13 26 is be VBZ cord-280571-ntgt5hy9 13 27 a a DT cord-280571-ntgt5hy9 13 28 key key JJ cord-280571-ntgt5hy9 13 29 component component NN cord-280571-ntgt5hy9 13 30 in in IN cord-280571-ntgt5hy9 13 31 restricting restrict VBG cord-280571-ntgt5hy9 13 32 antibiotic antibiotic JJ cord-280571-ntgt5hy9 13 33 use use NN cord-280571-ntgt5hy9 13 34 to to IN cord-280571-ntgt5hy9 13 35 those those DT cord-280571-ntgt5hy9 13 36 circumstances circumstance NNS cord-280571-ntgt5hy9 13 37 in in IN cord-280571-ntgt5hy9 13 38 which which WDT cord-280571-ntgt5hy9 13 39 antibiotic antibiotic JJ cord-280571-ntgt5hy9 13 40 therapy therapy NN cord-280571-ntgt5hy9 13 41 is be VBZ cord-280571-ntgt5hy9 13 42 clearly clearly RB cord-280571-ntgt5hy9 13 43 indicated indicate VBN cord-280571-ntgt5hy9 13 44 [ [ -LRB- cord-280571-ntgt5hy9 13 45 1 1 CD cord-280571-ntgt5hy9 13 46 ] ] -RRB- cord-280571-ntgt5hy9 13 47 . . . cord-280571-ntgt5hy9 14 1 Initial initial JJ cord-280571-ntgt5hy9 14 2 empiric empiric JJ cord-280571-ntgt5hy9 14 3 therapeutic therapeutic JJ cord-280571-ntgt5hy9 14 4 choices choice NNS cord-280571-ntgt5hy9 14 5 may may MD cord-280571-ntgt5hy9 14 6 be be VB cord-280571-ntgt5hy9 14 7 standardized standardize VBN cord-280571-ntgt5hy9 14 8 and and CC cord-280571-ntgt5hy9 14 9 initiated initiate VBN cord-280571-ntgt5hy9 14 10 on on IN cord-280571-ntgt5hy9 14 11 the the DT cord-280571-ntgt5hy9 14 12 basis basis NN cord-280571-ntgt5hy9 14 13 of of IN cord-280571-ntgt5hy9 14 14 patient patient JJ cord-280571-ntgt5hy9 14 15 clinical clinical JJ cord-280571-ntgt5hy9 14 16 status status NN cord-280571-ntgt5hy9 14 17 , , , cord-280571-ntgt5hy9 14 18 underlying underlie VBG cord-280571-ntgt5hy9 14 19 disease disease NN cord-280571-ntgt5hy9 14 20 , , , cord-280571-ntgt5hy9 14 21 and/or and/or CC cord-280571-ntgt5hy9 14 22 risk risk NN cord-280571-ntgt5hy9 14 23 for for IN cord-280571-ntgt5hy9 14 24 infection infection NN cord-280571-ntgt5hy9 14 25 with with IN cord-280571-ntgt5hy9 14 26 a a DT cord-280571-ntgt5hy9 14 27 multidrug multidrug NN cord-280571-ntgt5hy9 14 28 - - HYPH cord-280571-ntgt5hy9 14 29 resistant resistant JJ cord-280571-ntgt5hy9 14 30 pathogen pathogen NN cord-280571-ntgt5hy9 14 31 . . . cord-280571-ntgt5hy9 15 1 However however RB cord-280571-ntgt5hy9 15 2 , , , cord-280571-ntgt5hy9 15 3 subsequent subsequent JJ cord-280571-ntgt5hy9 15 4 bacterial bacterial JJ cord-280571-ntgt5hy9 15 5 pathogen pathogen NN cord-280571-ntgt5hy9 15 6 identification identification NN cord-280571-ntgt5hy9 15 7 and and CC cord-280571-ntgt5hy9 15 8 accurate accurate JJ cord-280571-ntgt5hy9 15 9 susceptibility susceptibility NN cord-280571-ntgt5hy9 15 10 data datum NNS cord-280571-ntgt5hy9 15 11 should should MD cord-280571-ntgt5hy9 15 12 assist assist VB cord-280571-ntgt5hy9 15 13 in in IN cord-280571-ntgt5hy9 15 14 promoting promote VBG cord-280571-ntgt5hy9 15 15 switches switch NNS cord-280571-ntgt5hy9 15 16 to to IN cord-280571-ntgt5hy9 15 17 targeted target VBN cord-280571-ntgt5hy9 15 18 specific specific JJ cord-280571-ntgt5hy9 15 19 therapies therapy NNS cord-280571-ntgt5hy9 15 20 and and CC cord-280571-ntgt5hy9 15 21 reduce reduce VB cord-280571-ntgt5hy9 15 22 the the DT cord-280571-ntgt5hy9 15 23 use use NN cord-280571-ntgt5hy9 15 24 of of IN cord-280571-ntgt5hy9 15 25 broad broad JJ cord-280571-ntgt5hy9 15 26 - - HYPH cord-280571-ntgt5hy9 15 27 spectrum spectrum NN cord-280571-ntgt5hy9 15 28 antibiotics antibiotic NNS cord-280571-ntgt5hy9 15 29 when when WRB cord-280571-ntgt5hy9 15 30 not not RB cord-280571-ntgt5hy9 15 31 indicated indicate VBN cord-280571-ntgt5hy9 15 32 , , , cord-280571-ntgt5hy9 15 33 thereby thereby RB cord-280571-ntgt5hy9 15 34 promoting promote VBG cord-280571-ntgt5hy9 15 35 good good JJ cord-280571-ntgt5hy9 15 36 antibiotic antibiotic JJ cord-280571-ntgt5hy9 15 37 stewardship stewardship NN cord-280571-ntgt5hy9 15 38 [ [ -LRB- cord-280571-ntgt5hy9 15 39 2 2 CD cord-280571-ntgt5hy9 15 40 ] ] -RRB- cord-280571-ntgt5hy9 15 41 . . . cord-280571-ntgt5hy9 16 1 Viral viral JJ cord-280571-ntgt5hy9 16 2 infections infection NNS cord-280571-ntgt5hy9 16 3 probably probably RB cord-280571-ntgt5hy9 16 4 cause cause VBP cord-280571-ntgt5hy9 16 5 between between IN cord-280571-ntgt5hy9 16 6 75 75 CD cord-280571-ntgt5hy9 16 7 % % NN cord-280571-ntgt5hy9 16 8 and and CC cord-280571-ntgt5hy9 16 9 80 80 CD cord-280571-ntgt5hy9 16 10 % % NN cord-280571-ntgt5hy9 16 11 of of IN cord-280571-ntgt5hy9 16 12 respiratory respiratory JJ cord-280571-ntgt5hy9 16 13 tract tract NN cord-280571-ntgt5hy9 16 14 diseases disease NNS cord-280571-ntgt5hy9 16 15 . . . cord-280571-ntgt5hy9 17 1 Nonetheless nonetheless RB cord-280571-ntgt5hy9 17 2 , , , cord-280571-ntgt5hy9 17 3 it -PRON- PRP cord-280571-ntgt5hy9 17 4 is be VBZ cord-280571-ntgt5hy9 17 5 estimated estimate VBN cord-280571-ntgt5hy9 17 6 that that IN cord-280571-ntgt5hy9 17 7 22.6 22.6 CD cord-280571-ntgt5hy9 17 8 million million CD cord-280571-ntgt5hy9 17 9 ( ( -LRB- cord-280571-ntgt5hy9 17 10 55 55 CD cord-280571-ntgt5hy9 17 11 % % NN cord-280571-ntgt5hy9 17 12 ) ) -RRB- cord-280571-ntgt5hy9 17 13 of of IN cord-280571-ntgt5hy9 17 14 41 41 CD cord-280571-ntgt5hy9 17 15 million million CD cord-280571-ntgt5hy9 17 16 antibiotic antibiotic JJ cord-280571-ntgt5hy9 17 17 prescriptions prescription NNS cord-280571-ntgt5hy9 17 18 for for IN cord-280571-ntgt5hy9 17 19 respiratory respiratory JJ cord-280571-ntgt5hy9 17 20 tract tract NN cord-280571-ntgt5hy9 17 21 infections infection NNS cord-280571-ntgt5hy9 17 22 , , , cord-280571-ntgt5hy9 17 23 including include VBG cord-280571-ntgt5hy9 17 24 both both DT cord-280571-ntgt5hy9 17 25 lower low JJR cord-280571-ntgt5hy9 17 26 and and CC cord-280571-ntgt5hy9 17 27 upper upper JJ cord-280571-ntgt5hy9 17 28 respiratory respiratory JJ cord-280571-ntgt5hy9 17 29 infections infection NNS cord-280571-ntgt5hy9 17 30 , , , cord-280571-ntgt5hy9 17 31 were be VBD cord-280571-ntgt5hy9 17 32 for for IN cord-280571-ntgt5hy9 17 33 causes cause NNS cord-280571-ntgt5hy9 17 34 unlikely unlikely JJ cord-280571-ntgt5hy9 17 35 to to TO cord-280571-ntgt5hy9 17 36 have have VB cord-280571-ntgt5hy9 17 37 a a DT cord-280571-ntgt5hy9 17 38 bacterial bacterial JJ cord-280571-ntgt5hy9 17 39 etiology etiology NN cord-280571-ntgt5hy9 17 40 [ [ -LRB- cord-280571-ntgt5hy9 17 41 3 3 CD cord-280571-ntgt5hy9 17 42 ] ] -RRB- cord-280571-ntgt5hy9 17 43 . . . cord-280571-ntgt5hy9 18 1 Although although IN cord-280571-ntgt5hy9 18 2 in in IN cord-280571-ntgt5hy9 18 3 many many JJ cord-280571-ntgt5hy9 18 4 cases case NNS cord-280571-ntgt5hy9 18 5 of of IN cord-280571-ntgt5hy9 18 6 otitis otitis NN cord-280571-ntgt5hy9 18 7 and and CC cord-280571-ntgt5hy9 18 8 sinusitis sinusitis NN cord-280571-ntgt5hy9 18 9 and and CC cord-280571-ntgt5hy9 18 10 probably probably RB cord-280571-ntgt5hy9 18 11 20%-40 20%-40 CD cord-280571-ntgt5hy9 18 12 % % NN cord-280571-ntgt5hy9 18 13 of of IN cord-280571-ntgt5hy9 18 14 cases case NNS cord-280571-ntgt5hy9 18 15 of of IN cord-280571-ntgt5hy9 18 16 community community NN cord-280571-ntgt5hy9 18 17 - - HYPH cord-280571-ntgt5hy9 18 18 acquired acquire VBN cord-280571-ntgt5hy9 18 19 pneumonia pneumonia NN cord-280571-ntgt5hy9 18 20 a a DT cord-280571-ntgt5hy9 18 21 bacterial bacterial JJ cord-280571-ntgt5hy9 18 22 superinfection superinfection NN cord-280571-ntgt5hy9 18 23 may may MD cord-280571-ntgt5hy9 18 24 occur occur VB cord-280571-ntgt5hy9 18 25 , , , cord-280571-ntgt5hy9 18 26 respiratory respiratory JJ cord-280571-ntgt5hy9 18 27 infections infection NNS cord-280571-ntgt5hy9 18 28 due due JJ cord-280571-ntgt5hy9 18 29 to to IN cord-280571-ntgt5hy9 18 30 a a DT cord-280571-ntgt5hy9 18 31 virus(es virus(es CD cord-280571-ntgt5hy9 18 32 ) ) -RRB- cord-280571-ntgt5hy9 18 33 alone alone RB cord-280571-ntgt5hy9 18 34 are be VBP cord-280571-ntgt5hy9 18 35 common common JJ cord-280571-ntgt5hy9 18 36 in in IN cord-280571-ntgt5hy9 18 37 the the DT cord-280571-ntgt5hy9 18 38 adult adult NN cord-280571-ntgt5hy9 18 39 and and CC cord-280571-ntgt5hy9 18 40 pediatric pediatric JJ cord-280571-ntgt5hy9 18 41 outpatient outpatient NN cord-280571-ntgt5hy9 18 42 populations population NNS cord-280571-ntgt5hy9 18 43 . . . cord-280571-ntgt5hy9 19 1 In in IN cord-280571-ntgt5hy9 19 2 addition addition NN cord-280571-ntgt5hy9 19 3 , , , cord-280571-ntgt5hy9 19 4 the the DT cord-280571-ntgt5hy9 19 5 vast vast JJ cord-280571-ntgt5hy9 19 6 majority majority NN cord-280571-ntgt5hy9 19 7 of of IN cord-280571-ntgt5hy9 19 8 respiratory respiratory JJ cord-280571-ntgt5hy9 19 9 tract tract NN cord-280571-ntgt5hy9 19 10 infections infection NNS cord-280571-ntgt5hy9 19 11 in in IN cord-280571-ntgt5hy9 19 12 nonimmunocompromised nonimmunocompromise VBN cord-280571-ntgt5hy9 19 13 hospitalized hospitalize VBN cord-280571-ntgt5hy9 19 14 children child NNS cord-280571-ntgt5hy9 19 15 ( ( -LRB- cord-280571-ntgt5hy9 19 16 especially especially RB cord-280571-ntgt5hy9 19 17 those those DT cord-280571-ntgt5hy9 19 18 , , , cord-280571-ntgt5hy9 19 19 5 5 CD cord-280571-ntgt5hy9 19 20 years year NNS cord-280571-ntgt5hy9 19 21 of of IN cord-280571-ntgt5hy9 19 22 age age NN cord-280571-ntgt5hy9 19 23 ) ) -RRB- cord-280571-ntgt5hy9 19 24 are be VBP cord-280571-ntgt5hy9 19 25 due due JJ cord-280571-ntgt5hy9 19 26 to to IN cord-280571-ntgt5hy9 19 27 1 1 CD cord-280571-ntgt5hy9 19 28 or or CC cord-280571-ntgt5hy9 19 29 more more JJR cord-280571-ntgt5hy9 19 30 viruses virus NNS cord-280571-ntgt5hy9 19 31 , , , cord-280571-ntgt5hy9 19 32 without without IN cord-280571-ntgt5hy9 19 33 a a DT cord-280571-ntgt5hy9 19 34 secondary secondary JJ cord-280571-ntgt5hy9 19 35 bacterial bacterial JJ cord-280571-ntgt5hy9 19 36 infection infection NN cord-280571-ntgt5hy9 19 37 . . . cord-280571-ntgt5hy9 20 1 The the DT cord-280571-ntgt5hy9 20 2 overuse overuse NN cord-280571-ntgt5hy9 20 3 of of IN cord-280571-ntgt5hy9 20 4 antibiotics antibiotic NNS cord-280571-ntgt5hy9 20 5 for for IN cord-280571-ntgt5hy9 20 6 the the DT cord-280571-ntgt5hy9 20 7 treatment treatment NN cord-280571-ntgt5hy9 20 8 of of IN cord-280571-ntgt5hy9 20 9 outpatients outpatient NNS cord-280571-ntgt5hy9 20 10 is be VBZ cord-280571-ntgt5hy9 20 11 primarily primarily RB cord-280571-ntgt5hy9 20 12 due due JJ cord-280571-ntgt5hy9 20 13 to to IN cord-280571-ntgt5hy9 20 14 the the DT cord-280571-ntgt5hy9 20 15 fact fact NN cord-280571-ntgt5hy9 20 16 that that IN cord-280571-ntgt5hy9 20 17 in in IN cord-280571-ntgt5hy9 20 18 adults adult NNS cord-280571-ntgt5hy9 20 19 respiratory respiratory JJ cord-280571-ntgt5hy9 20 20 virus virus NN cord-280571-ntgt5hy9 20 21 testing testing NN cord-280571-ntgt5hy9 20 22 is be VBZ cord-280571-ntgt5hy9 20 23 either either CC cord-280571-ntgt5hy9 20 24 not not RB cord-280571-ntgt5hy9 20 25 performed perform VBN cord-280571-ntgt5hy9 20 26 or or CC cord-280571-ntgt5hy9 20 27 generally generally RB cord-280571-ntgt5hy9 20 28 limited limited JJ cord-280571-ntgt5hy9 20 29 to to IN cord-280571-ntgt5hy9 20 30 rapid rapid JJ cord-280571-ntgt5hy9 20 31 antigen antigen NN cord-280571-ntgt5hy9 20 32 direct direct JJ cord-280571-ntgt5hy9 20 33 tests test NNS cord-280571-ntgt5hy9 20 34 ( ( -LRB- cord-280571-ntgt5hy9 20 35 RADTs radt NNS cord-280571-ntgt5hy9 20 36 ) ) -RRB- cord-280571-ntgt5hy9 20 37 for for IN cord-280571-ntgt5hy9 20 38 influenza influenza NN cord-280571-ntgt5hy9 20 39 . . . cord-280571-ntgt5hy9 21 1 Testing test VBG cord-280571-ntgt5hy9 21 2 for for IN cord-280571-ntgt5hy9 21 3 the the DT cord-280571-ntgt5hy9 21 4 elderly elderly JJ cord-280571-ntgt5hy9 21 5 , , , cord-280571-ntgt5hy9 21 6 for for IN cord-280571-ntgt5hy9 21 7 persons person NNS cord-280571-ntgt5hy9 21 8 with with IN cord-280571-ntgt5hy9 21 9 chronic chronic JJ cord-280571-ntgt5hy9 21 10 obstructive obstructive JJ cord-280571-ntgt5hy9 21 11 pulmonary pulmonary JJ cord-280571-ntgt5hy9 21 12 disease disease NN cord-280571-ntgt5hy9 21 13 , , , cord-280571-ntgt5hy9 21 14 and and CC cord-280571-ntgt5hy9 21 15 for for IN cord-280571-ntgt5hy9 21 16 pediatric pediatric JJ cord-280571-ntgt5hy9 21 17 patients patient NNS cord-280571-ntgt5hy9 21 18 is be VBZ cord-280571-ntgt5hy9 21 19 limited limit VBN cord-280571-ntgt5hy9 21 20 to to IN cord-280571-ntgt5hy9 21 21 RADTs radt NNS cord-280571-ntgt5hy9 21 22 for for IN cord-280571-ntgt5hy9 21 23 influenza influenza NN cord-280571-ntgt5hy9 21 24 and and CC cord-280571-ntgt5hy9 21 25 respiratory respiratory JJ cord-280571-ntgt5hy9 21 26 syncytial syncytial JJ cord-280571-ntgt5hy9 21 27 virus virus NN cord-280571-ntgt5hy9 21 28 ( ( -LRB- cord-280571-ntgt5hy9 21 29 RSV RSV NNP cord-280571-ntgt5hy9 21 30 ) ) -RRB- cord-280571-ntgt5hy9 21 31 . . . cord-280571-ntgt5hy9 22 1 RADTs radt NNS cord-280571-ntgt5hy9 22 2 have have VBP cord-280571-ntgt5hy9 22 3 highly highly RB cord-280571-ntgt5hy9 22 4 variable variable JJ cord-280571-ntgt5hy9 22 5 sensitivities sensitivity NNS cord-280571-ntgt5hy9 22 6 ( ( -LRB- cord-280571-ntgt5hy9 22 7 10%-75 10%-75 CD cord-280571-ntgt5hy9 22 8 % % NN cord-280571-ntgt5hy9 22 9 ) ) -RRB- cord-280571-ntgt5hy9 22 10 and and CC cord-280571-ntgt5hy9 22 11 specificities specificity NNS cord-280571-ntgt5hy9 22 12 ( ( -LRB- cord-280571-ntgt5hy9 22 13 50%-100 50%-100 CD cord-280571-ntgt5hy9 22 14 % % NN cord-280571-ntgt5hy9 22 15 ) ) -RRB- cord-280571-ntgt5hy9 22 16 depending depend VBG cord-280571-ntgt5hy9 22 17 on on IN cord-280571-ntgt5hy9 22 18 the the DT cord-280571-ntgt5hy9 22 19 viral viral JJ cord-280571-ntgt5hy9 22 20 target target NN cord-280571-ntgt5hy9 22 21 , , , cord-280571-ntgt5hy9 22 22 age age NN cord-280571-ntgt5hy9 22 23 of of IN cord-280571-ntgt5hy9 22 24 the the DT cord-280571-ntgt5hy9 22 25 patient patient NN cord-280571-ntgt5hy9 22 26 , , , cord-280571-ntgt5hy9 22 27 sample sample NN cord-280571-ntgt5hy9 22 28 collection collection NN cord-280571-ntgt5hy9 22 29 , , , cord-280571-ntgt5hy9 22 30 and and CC cord-280571-ntgt5hy9 22 31 duration duration NN cord-280571-ntgt5hy9 22 32 of of IN cord-280571-ntgt5hy9 22 33 symptoms symptom NNS cord-280571-ntgt5hy9 22 34 prior prior RB cord-280571-ntgt5hy9 22 35 to to IN cord-280571-ntgt5hy9 22 36 testing test VBG cord-280571-ntgt5hy9 22 37 [ [ -LRB- cord-280571-ntgt5hy9 22 38 4 4 CD cord-280571-ntgt5hy9 22 39 ] ] -RRB- cord-280571-ntgt5hy9 22 40 [ [ -LRB- cord-280571-ntgt5hy9 22 41 5 5 CD cord-280571-ntgt5hy9 22 42 ] ] -RRB- cord-280571-ntgt5hy9 22 43 [ [ -LRB- cord-280571-ntgt5hy9 22 44 6 6 CD cord-280571-ntgt5hy9 22 45 ] ] -RRB- cord-280571-ntgt5hy9 22 46 . . . cord-280571-ntgt5hy9 23 1 In in IN cord-280571-ntgt5hy9 23 2 general general JJ cord-280571-ntgt5hy9 23 3 , , , cord-280571-ntgt5hy9 23 4 RADTs radt NNS cord-280571-ntgt5hy9 23 5 perform perform VBP cord-280571-ntgt5hy9 23 6 better well RBR cord-280571-ntgt5hy9 23 7 when when WRB cord-280571-ntgt5hy9 23 8 testing test VBG cord-280571-ntgt5hy9 23 9 pediatric pediatric JJ cord-280571-ntgt5hy9 23 10 samples sample NNS cord-280571-ntgt5hy9 23 11 , , , cord-280571-ntgt5hy9 23 12 because because IN cord-280571-ntgt5hy9 23 13 children child NNS cord-280571-ntgt5hy9 23 14 shed shed VBD cord-280571-ntgt5hy9 23 15 higher high JJR cord-280571-ntgt5hy9 23 16 titers titer NNS cord-280571-ntgt5hy9 23 17 of of IN cord-280571-ntgt5hy9 23 18 virus virus NN cord-280571-ntgt5hy9 23 19 and and CC cord-280571-ntgt5hy9 23 20 for for IN cord-280571-ntgt5hy9 23 21 longer long JJR cord-280571-ntgt5hy9 23 22 time time NN cord-280571-ntgt5hy9 23 23 periods period NNS cord-280571-ntgt5hy9 23 24 than than IN cord-280571-ntgt5hy9 23 25 adults adult NNS cord-280571-ntgt5hy9 23 26 [ [ -LRB- cord-280571-ntgt5hy9 23 27 4 4 CD cord-280571-ntgt5hy9 23 28 , , , cord-280571-ntgt5hy9 23 29 [ [ -LRB- cord-280571-ntgt5hy9 23 30 7 7 CD cord-280571-ntgt5hy9 23 31 ] ] -RRB- cord-280571-ntgt5hy9 23 32 [ [ -LRB- cord-280571-ntgt5hy9 23 33 8 8 CD cord-280571-ntgt5hy9 23 34 ] ] -RRB- cord-280571-ntgt5hy9 23 35 [ [ -LRB- cord-280571-ntgt5hy9 23 36 9 9 CD cord-280571-ntgt5hy9 23 37 ] ] -RRB- cord-280571-ntgt5hy9 23 38 . . . cord-280571-ntgt5hy9 24 1 In in IN cord-280571-ntgt5hy9 24 2 addition addition NN cord-280571-ntgt5hy9 24 3 to to IN cord-280571-ntgt5hy9 24 4 RADTs radt NNS cord-280571-ntgt5hy9 24 5 , , , cord-280571-ntgt5hy9 24 6 there there EX cord-280571-ntgt5hy9 24 7 are be VBP cord-280571-ntgt5hy9 24 8 U.S. U.S. NNP cord-280571-ntgt5hy9 24 9 Food Food NNP cord-280571-ntgt5hy9 24 10 and and CC cord-280571-ntgt5hy9 24 11 Drug Drug NNP cord-280571-ntgt5hy9 24 12 Administration Administration NNP cord-280571-ntgt5hy9 24 13 ( ( -LRB- cord-280571-ntgt5hy9 24 14 FDA)-approved FDA)-approved NNP cord-280571-ntgt5hy9 24 15 / / SYM cord-280571-ntgt5hy9 24 16 cleared clear VBN cord-280571-ntgt5hy9 24 17 nonmolecular nonmolecular NNP cord-280571-ntgt5hy9 24 18 - - HYPH cord-280571-ntgt5hy9 24 19 based base VBN cord-280571-ntgt5hy9 24 20 viral viral JJ cord-280571-ntgt5hy9 24 21 diagnostic diagnostic JJ cord-280571-ntgt5hy9 24 22 methods method NNS cord-280571-ntgt5hy9 24 23 with with IN cord-280571-ntgt5hy9 24 24 a a DT cord-280571-ntgt5hy9 24 25 more more RBR cord-280571-ntgt5hy9 24 26 rapid rapid JJ cord-280571-ntgt5hy9 24 27 time time NN cord-280571-ntgt5hy9 24 28 to to TO cord-280571-ntgt5hy9 24 29 result result VB cord-280571-ntgt5hy9 24 30 , , , cord-280571-ntgt5hy9 24 31 compared compare VBN cord-280571-ntgt5hy9 24 32 with with IN cord-280571-ntgt5hy9 24 33 traditional traditional JJ cord-280571-ntgt5hy9 24 34 viral viral JJ cord-280571-ntgt5hy9 24 35 tube tube NN cord-280571-ntgt5hy9 24 36 culture culture NN cord-280571-ntgt5hy9 24 37 , , , cord-280571-ntgt5hy9 24 38 eg eg IN cord-280571-ntgt5hy9 24 39 , , , cord-280571-ntgt5hy9 24 40 direct direct JJ cord-280571-ntgt5hy9 24 41 fluorescent fluorescent JJ cord-280571-ntgt5hy9 24 42 antibody antibody NN cord-280571-ntgt5hy9 24 43 ( ( -LRB- cord-280571-ntgt5hy9 24 44 DFA DFA NNP cord-280571-ntgt5hy9 24 45 ) ) -RRB- cord-280571-ntgt5hy9 24 46 testing testing NN cord-280571-ntgt5hy9 24 47 and and CC cord-280571-ntgt5hy9 24 48 rapid rapid JJ cord-280571-ntgt5hy9 24 49 cell cell NN cord-280571-ntgt5hy9 24 50 culture culture NN cord-280571-ntgt5hy9 24 51 . . . cord-280571-ntgt5hy9 25 1 Both both DT cord-280571-ntgt5hy9 25 2 methods method NNS cord-280571-ntgt5hy9 25 3 can can MD cord-280571-ntgt5hy9 25 4 readily readily RB cord-280571-ntgt5hy9 25 5 detect detect VB cord-280571-ntgt5hy9 25 6 7 7 CD cord-280571-ntgt5hy9 25 7 of of IN cord-280571-ntgt5hy9 25 8 the the DT cord-280571-ntgt5hy9 25 9 common common JJ cord-280571-ntgt5hy9 25 10 respiratory respiratory JJ cord-280571-ntgt5hy9 25 11 viruses virus NNS cord-280571-ntgt5hy9 25 12 ( ( -LRB- cord-280571-ntgt5hy9 25 13 adenovirus adenovirus NN cord-280571-ntgt5hy9 25 14 , , , cord-280571-ntgt5hy9 25 15 influenza influenza NN cord-280571-ntgt5hy9 25 16 A a NN cord-280571-ntgt5hy9 25 17 , , , cord-280571-ntgt5hy9 25 18 influenza influenza NN cord-280571-ntgt5hy9 25 19 B B NNP cord-280571-ntgt5hy9 25 20 , , , cord-280571-ntgt5hy9 25 21 parainfluenza parainfluenza NNP cord-280571-ntgt5hy9 25 22 1 1 CD cord-280571-ntgt5hy9 25 23 , , , cord-280571-ntgt5hy9 25 24 2 2 CD cord-280571-ntgt5hy9 25 25 , , , cord-280571-ntgt5hy9 25 26 and and CC cord-280571-ntgt5hy9 25 27 3 3 LS cord-280571-ntgt5hy9 25 28 [ [ -LRB- cord-280571-ntgt5hy9 25 29 PIV-1 PIV-1 NNP cord-280571-ntgt5hy9 25 30 , , , cord-280571-ntgt5hy9 25 31 PIV-2 PIV-2 NNP cord-280571-ntgt5hy9 25 32 , , , cord-280571-ntgt5hy9 25 33 PIV-3 PIV-3 NNP cord-280571-ntgt5hy9 25 34 ] ] -RRB- cord-280571-ntgt5hy9 25 35 , , , cord-280571-ntgt5hy9 25 36 and and CC cord-280571-ntgt5hy9 25 37 RSV RSV NNP cord-280571-ntgt5hy9 25 38 ) ) -RRB- cord-280571-ntgt5hy9 25 39 . . . cord-280571-ntgt5hy9 26 1 In in IN cord-280571-ntgt5hy9 26 2 addition addition NN cord-280571-ntgt5hy9 26 3 , , , cord-280571-ntgt5hy9 26 4 DFA DFA NNP cord-280571-ntgt5hy9 26 5 testing testing NN cord-280571-ntgt5hy9 26 6 can can MD cord-280571-ntgt5hy9 26 7 detect detect VB cord-280571-ntgt5hy9 26 8 human human JJ cord-280571-ntgt5hy9 26 9 metapneumovirus metapneumovirus NNP cord-280571-ntgt5hy9 26 10 ( ( -LRB- cord-280571-ntgt5hy9 26 11 hMPV hMPV NNP cord-280571-ntgt5hy9 26 12 ) ) -RRB- cord-280571-ntgt5hy9 26 13 [ [ -LRB- cord-280571-ntgt5hy9 26 14 6 6 CD cord-280571-ntgt5hy9 26 15 ] ] -RRB- cord-280571-ntgt5hy9 26 16 . . . cord-280571-ntgt5hy9 27 1 The the DT cord-280571-ntgt5hy9 27 2 specificity specificity NN cord-280571-ntgt5hy9 27 3 of of IN cord-280571-ntgt5hy9 27 4 DFA DFA NNP cord-280571-ntgt5hy9 27 5 testing testing NN cord-280571-ntgt5hy9 27 6 and and CC cord-280571-ntgt5hy9 27 7 rapid rapid JJ cord-280571-ntgt5hy9 27 8 cell cell NN cord-280571-ntgt5hy9 27 9 culture culture NN cord-280571-ntgt5hy9 27 10 are be VBP cord-280571-ntgt5hy9 27 11 high high JJ cord-280571-ntgt5hy9 27 12 , , , cord-280571-ntgt5hy9 27 13 but but CC cord-280571-ntgt5hy9 27 14 the the DT cord-280571-ntgt5hy9 27 15 sensitivities sensitivity NNS cord-280571-ntgt5hy9 27 16 of of IN cord-280571-ntgt5hy9 27 17 the the DT cord-280571-ntgt5hy9 27 18 tests test NNS cord-280571-ntgt5hy9 27 19 can can MD cord-280571-ntgt5hy9 27 20 vary vary VB cord-280571-ntgt5hy9 27 21 from from IN cord-280571-ntgt5hy9 27 22 a a DT cord-280571-ntgt5hy9 27 23 low low NN cord-280571-ntgt5hy9 27 24 of of IN cord-280571-ntgt5hy9 27 25 50 50 CD cord-280571-ntgt5hy9 27 26 % % NN cord-280571-ntgt5hy9 27 27 ( ( -LRB- cord-280571-ntgt5hy9 27 28 RSV RSV NNP cord-280571-ntgt5hy9 27 29 culture culture NN cord-280571-ntgt5hy9 27 30 ) ) -RRB- cord-280571-ntgt5hy9 27 31 to to IN cord-280571-ntgt5hy9 27 32 a a DT cord-280571-ntgt5hy9 27 33 high high NN cord-280571-ntgt5hy9 27 34 of of IN cord-280571-ntgt5hy9 27 35 .80 .80 CD cord-280571-ntgt5hy9 27 36 % % NN cord-280571-ntgt5hy9 27 37 ( ( -LRB- cord-280571-ntgt5hy9 27 38 influenza influenza NN cord-280571-ntgt5hy9 27 39 A a NN cord-280571-ntgt5hy9 27 40 ) ) -RRB- cord-280571-ntgt5hy9 27 41 , , , cord-280571-ntgt5hy9 27 42 when when WRB cord-280571-ntgt5hy9 27 43 compared compare VBN cord-280571-ntgt5hy9 27 44 with with IN cord-280571-ntgt5hy9 27 45 nucleic nucleic JJ cord-280571-ntgt5hy9 27 46 acid acid NN cord-280571-ntgt5hy9 27 47 amplification amplification NN cord-280571-ntgt5hy9 27 48 tests test NNS cord-280571-ntgt5hy9 27 49 ( ( -LRB- cord-280571-ntgt5hy9 27 50 NAATs NAATs NNP cord-280571-ntgt5hy9 27 51 ) ) -RRB- cord-280571-ntgt5hy9 27 52 [ [ -LRB- cord-280571-ntgt5hy9 27 53 5 5 CD cord-280571-ntgt5hy9 27 54 , , , cord-280571-ntgt5hy9 27 55 6 6 CD cord-280571-ntgt5hy9 27 56 , , , cord-280571-ntgt5hy9 27 57 10 10 CD cord-280571-ntgt5hy9 27 58 ] ] -RRB- cord-280571-ntgt5hy9 27 59 . . . cord-280571-ntgt5hy9 28 1 DFA DFA NNP cord-280571-ntgt5hy9 28 2 testing testing NN cord-280571-ntgt5hy9 28 3 can can MD cord-280571-ntgt5hy9 28 4 be be VB cord-280571-ntgt5hy9 28 5 performed perform VBN cord-280571-ntgt5hy9 28 6 in in IN cord-280571-ntgt5hy9 28 7 as as RB cord-280571-ntgt5hy9 28 8 little little JJ cord-280571-ntgt5hy9 28 9 as as IN cord-280571-ntgt5hy9 28 10 30 30 CD cord-280571-ntgt5hy9 28 11 - - SYM cord-280571-ntgt5hy9 28 12 60 60 CD cord-280571-ntgt5hy9 28 13 min min NN cord-280571-ntgt5hy9 28 14 , , , cord-280571-ntgt5hy9 28 15 and and CC cord-280571-ntgt5hy9 28 16 shell shell NN cord-280571-ntgt5hy9 28 17 vial vial NN cord-280571-ntgt5hy9 28 18 and and CC cord-280571-ntgt5hy9 28 19 R R NNP cord-280571-ntgt5hy9 28 20 - - HYPH cord-280571-ntgt5hy9 28 21 Mix mix NN cord-280571-ntgt5hy9 28 22 rapid rapid JJ cord-280571-ntgt5hy9 28 23 cell cell NN cord-280571-ntgt5hy9 28 24 cultures culture NNS cord-280571-ntgt5hy9 29 1 ( ( -LRB- cord-280571-ntgt5hy9 29 2 Quidel Quidel NNP cord-280571-ntgt5hy9 29 3 / / SYM cord-280571-ntgt5hy9 29 4 Diagnostic Diagnostic NNP cord-280571-ntgt5hy9 29 5 Hybrids Hybrids NNPS cord-280571-ntgt5hy9 29 6 ) ) -RRB- cord-280571-ntgt5hy9 29 7 generally generally RB cord-280571-ntgt5hy9 29 8 identify identify VBP cord-280571-ntgt5hy9 29 9 respiratory respiratory JJ cord-280571-ntgt5hy9 29 10 viruses virus NNS cord-280571-ntgt5hy9 29 11 in in IN cord-280571-ntgt5hy9 29 12 24 24 CD cord-280571-ntgt5hy9 29 13 - - SYM cord-280571-ntgt5hy9 29 14 48 48 CD cord-280571-ntgt5hy9 29 15 h h NN cord-280571-ntgt5hy9 29 16 [ [ -LRB- cord-280571-ntgt5hy9 29 17 6 6 CD cord-280571-ntgt5hy9 29 18 ] ] -RRB- cord-280571-ntgt5hy9 29 19 . . . cord-280571-ntgt5hy9 30 1 If if IN cord-280571-ntgt5hy9 30 2 these these DT cord-280571-ntgt5hy9 30 3 tests test NNS cord-280571-ntgt5hy9 30 4 are be VBP cord-280571-ntgt5hy9 30 5 performed perform VBN cord-280571-ntgt5hy9 30 6 on on IN cord-280571-ntgt5hy9 30 7 site site NN cord-280571-ntgt5hy9 30 8 , , , cord-280571-ntgt5hy9 30 9 the the DT cord-280571-ntgt5hy9 30 10 time time NN cord-280571-ntgt5hy9 30 11 to to IN cord-280571-ntgt5hy9 30 12 virus virus NN cord-280571-ntgt5hy9 30 13 detection detection NN cord-280571-ntgt5hy9 30 14 can can MD cord-280571-ntgt5hy9 30 15 be be VB cord-280571-ntgt5hy9 30 16 within within IN cord-280571-ntgt5hy9 30 17 a a DT cord-280571-ntgt5hy9 30 18 time time NN cord-280571-ntgt5hy9 30 19 frame frame NN cord-280571-ntgt5hy9 30 20 that that WDT cord-280571-ntgt5hy9 30 21 could could MD cord-280571-ntgt5hy9 30 22 affect affect VB cord-280571-ntgt5hy9 30 23 patient patient JJ cord-280571-ntgt5hy9 30 24 management management NN cord-280571-ntgt5hy9 30 25 . . . cord-280571-ntgt5hy9 31 1 However however RB cord-280571-ntgt5hy9 31 2 , , , cord-280571-ntgt5hy9 31 3 these these DT cord-280571-ntgt5hy9 31 4 tests test NNS cord-280571-ntgt5hy9 31 5 are be VBP cord-280571-ntgt5hy9 31 6 not not RB cord-280571-ntgt5hy9 31 7 widely widely RB cord-280571-ntgt5hy9 31 8 available available JJ cord-280571-ntgt5hy9 31 9 outside outside IN cord-280571-ntgt5hy9 31 10 larger large JJR cord-280571-ntgt5hy9 31 11 hospitals hospital NNS cord-280571-ntgt5hy9 31 12 and and CC cord-280571-ntgt5hy9 31 13 reference reference NN cord-280571-ntgt5hy9 31 14 laboratories laboratory NNS cord-280571-ntgt5hy9 31 15 . . . cord-280571-ntgt5hy9 32 1 Although although IN cord-280571-ntgt5hy9 32 2 these these DT cord-280571-ntgt5hy9 32 3 8 8 CD cord-280571-ntgt5hy9 32 4 viruses virus NNS cord-280571-ntgt5hy9 32 5 are be VBP cord-280571-ntgt5hy9 32 6 responsible responsible JJ cord-280571-ntgt5hy9 32 7 for for IN cord-280571-ntgt5hy9 32 8 a a DT cord-280571-ntgt5hy9 32 9 large large JJ cord-280571-ntgt5hy9 32 10 number number NN cord-280571-ntgt5hy9 32 11 of of IN cord-280571-ntgt5hy9 32 12 respiratory respiratory JJ cord-280571-ntgt5hy9 32 13 tract tract NN cord-280571-ntgt5hy9 32 14 infections infection NNS cord-280571-ntgt5hy9 32 15 , , , cord-280571-ntgt5hy9 32 16 bocavirus bocavirus NNP cord-280571-ntgt5hy9 32 17 , , , cord-280571-ntgt5hy9 32 18 selected select VBN cord-280571-ntgt5hy9 32 19 coronaviruses coronaviruse NNS cord-280571-ntgt5hy9 32 20 ( ( -LRB- cord-280571-ntgt5hy9 32 21 229E 229e CD cord-280571-ntgt5hy9 32 22 , , , cord-280571-ntgt5hy9 32 23 OC43 OC43 NNP cord-280571-ntgt5hy9 32 24 , , , cord-280571-ntgt5hy9 32 25 NL63 NL63 NNP cord-280571-ntgt5hy9 32 26 , , , cord-280571-ntgt5hy9 32 27 and and CC cord-280571-ntgt5hy9 32 28 HKU-1 HKU-1 NNP cord-280571-ntgt5hy9 32 29 ) ) -RRB- cord-280571-ntgt5hy9 32 30 , , , cord-280571-ntgt5hy9 32 31 parainfluenza parainfluenza NNP cord-280571-ntgt5hy9 32 32 4 4 CD cord-280571-ntgt5hy9 32 33 , , , cord-280571-ntgt5hy9 32 34 and and CC cord-280571-ntgt5hy9 32 35 rhinovirus rhinovirus NN cord-280571-ntgt5hy9 32 36 are be VBP cord-280571-ntgt5hy9 32 37 also also RB cord-280571-ntgt5hy9 32 38 important important JJ cord-280571-ntgt5hy9 32 39 causes cause NNS cord-280571-ntgt5hy9 32 40 of of IN cord-280571-ntgt5hy9 32 41 respiratory respiratory JJ cord-280571-ntgt5hy9 32 42 disease disease NN cord-280571-ntgt5hy9 32 43 and and CC cord-280571-ntgt5hy9 32 44 are be VBP cord-280571-ntgt5hy9 32 45 generally generally RB cord-280571-ntgt5hy9 32 46 only only RB cord-280571-ntgt5hy9 32 47 detected detect VBN cord-280571-ntgt5hy9 32 48 using use VBG cord-280571-ntgt5hy9 32 49 NAATs NAATs NNP cord-280571-ntgt5hy9 32 50 . . . cord-280571-ntgt5hy9 33 1 Because because IN cord-280571-ntgt5hy9 33 2 antiviral antiviral JJ cord-280571-ntgt5hy9 33 3 therapies therapy NNS cord-280571-ntgt5hy9 33 4 are be VBP cord-280571-ntgt5hy9 33 5 currently currently RB cord-280571-ntgt5hy9 33 6 limited limit VBN cord-280571-ntgt5hy9 33 7 to to IN cord-280571-ntgt5hy9 33 8 the the DT cord-280571-ntgt5hy9 33 9 treatment treatment NN cord-280571-ntgt5hy9 33 10 of of IN cord-280571-ntgt5hy9 33 11 influenza influenza NN cord-280571-ntgt5hy9 33 12 A A NNP cord-280571-ntgt5hy9 33 13 , , , cord-280571-ntgt5hy9 33 14 influenza influenza NN cord-280571-ntgt5hy9 33 15 B b NN cord-280571-ntgt5hy9 33 16 , , , cord-280571-ntgt5hy9 33 17 cytomegalovirus cytomegalovirus NNP cord-280571-ntgt5hy9 33 18 pneumonia pneumonia NN cord-280571-ntgt5hy9 33 19 , , , cord-280571-ntgt5hy9 33 20 and and CC cord-280571-ntgt5hy9 33 21 varicella varicella NN cord-280571-ntgt5hy9 33 22 zoster zoster NNP cord-280571-ntgt5hy9 33 23 virus virus NN cord-280571-ntgt5hy9 33 24 pneumonia pneumonia NN cord-280571-ntgt5hy9 33 25 , , , cord-280571-ntgt5hy9 33 26 it -PRON- PRP cord-280571-ntgt5hy9 33 27 is be VBZ cord-280571-ntgt5hy9 33 28 often often RB cord-280571-ntgt5hy9 33 29 argued argue VBN cord-280571-ntgt5hy9 33 30 that that IN cord-280571-ntgt5hy9 33 31 the the DT cord-280571-ntgt5hy9 33 32 specific specific JJ cord-280571-ntgt5hy9 33 33 identification identification NN cord-280571-ntgt5hy9 33 34 of of IN cord-280571-ntgt5hy9 33 35 other other JJ cord-280571-ntgt5hy9 33 36 viruses virus NNS cord-280571-ntgt5hy9 33 37 is be VBZ cord-280571-ntgt5hy9 33 38 not not RB cord-280571-ntgt5hy9 33 39 relevant relevant JJ cord-280571-ntgt5hy9 33 40 , , , cord-280571-ntgt5hy9 33 41 because because IN cord-280571-ntgt5hy9 33 42 the the DT cord-280571-ntgt5hy9 33 43 information information NN cord-280571-ntgt5hy9 33 44 would would MD cord-280571-ntgt5hy9 33 45 not not RB cord-280571-ntgt5hy9 33 46 change change VB cord-280571-ntgt5hy9 33 47 patient patient JJ cord-280571-ntgt5hy9 33 48 management management NN cord-280571-ntgt5hy9 33 49 . . . cord-280571-ntgt5hy9 34 1 From from IN cord-280571-ntgt5hy9 34 2 a a DT cord-280571-ntgt5hy9 34 3 treatment treatment NN cord-280571-ntgt5hy9 34 4 standpoint standpoint NN cord-280571-ntgt5hy9 34 5 , , , cord-280571-ntgt5hy9 34 6 this this DT cord-280571-ntgt5hy9 34 7 may may MD cord-280571-ntgt5hy9 34 8 currently currently RB cord-280571-ntgt5hy9 34 9 be be VB cord-280571-ntgt5hy9 34 10 true true JJ cord-280571-ntgt5hy9 34 11 ; ; : cord-280571-ntgt5hy9 34 12 however however RB cord-280571-ntgt5hy9 34 13 , , , cord-280571-ntgt5hy9 34 14 the the DT cord-280571-ntgt5hy9 34 15 respiratory respiratory JJ cord-280571-ntgt5hy9 34 16 viruses virus NNS cord-280571-ntgt5hy9 34 17 cause cause VBP cord-280571-ntgt5hy9 34 18 similar similar JJ cord-280571-ntgt5hy9 34 19 illnesses illness NNS cord-280571-ntgt5hy9 34 20 , , , cord-280571-ntgt5hy9 34 21 and and CC cord-280571-ntgt5hy9 34 22 diagnosis diagnosis NN cord-280571-ntgt5hy9 34 23 based base VBN cord-280571-ntgt5hy9 34 24 on on IN cord-280571-ntgt5hy9 34 25 clinical clinical JJ cord-280571-ntgt5hy9 34 26 symptoms symptom NNS cord-280571-ntgt5hy9 34 27 alone alone RB cord-280571-ntgt5hy9 34 28 can can MD cord-280571-ntgt5hy9 34 29 be be VB cord-280571-ntgt5hy9 34 30 highly highly RB cord-280571-ntgt5hy9 34 31 inaccurate inaccurate JJ cord-280571-ntgt5hy9 34 32 [ [ -LRB- cord-280571-ntgt5hy9 34 33 11 11 CD cord-280571-ntgt5hy9 34 34 ] ] -RRB- cord-280571-ntgt5hy9 34 35 . . . cord-280571-ntgt5hy9 35 1 For for IN cord-280571-ntgt5hy9 35 2 example example NN cord-280571-ntgt5hy9 35 3 , , , cord-280571-ntgt5hy9 35 4 a a DT cord-280571-ntgt5hy9 35 5 study study NN cord-280571-ntgt5hy9 35 6 by by IN cord-280571-ntgt5hy9 35 7 Poehling Poehling NNP cord-280571-ntgt5hy9 35 8 et et FW cord-280571-ntgt5hy9 35 9 al al NNP cord-280571-ntgt5hy9 35 10 revealed reveal VBD cord-280571-ntgt5hy9 35 11 that that IN cord-280571-ntgt5hy9 35 12 physicians physician NNS cord-280571-ntgt5hy9 35 13 who who WP cord-280571-ntgt5hy9 35 14 used use VBD cord-280571-ntgt5hy9 35 15 only only JJ cord-280571-ntgt5hy9 35 16 clinical clinical JJ cord-280571-ntgt5hy9 35 17 symptoms symptom NNS cord-280571-ntgt5hy9 35 18 recognized recognize VBN cord-280571-ntgt5hy9 35 19 influenza influenza NN cord-280571-ntgt5hy9 35 20 in in IN cord-280571-ntgt5hy9 35 21 only only RB cord-280571-ntgt5hy9 35 22 28 28 CD cord-280571-ntgt5hy9 35 23 % % NN cord-280571-ntgt5hy9 35 24 of of IN cord-280571-ntgt5hy9 35 25 hospitalized hospitalize VBN cord-280571-ntgt5hy9 35 26 children child NNS cord-280571-ntgt5hy9 35 27 and and CC cord-280571-ntgt5hy9 35 28 17 17 CD cord-280571-ntgt5hy9 35 29 % % NN cord-280571-ntgt5hy9 35 30 of of IN cord-280571-ntgt5hy9 35 31 nonhospitalized nonhospitalized JJ cord-280571-ntgt5hy9 35 32 children child NNS cord-280571-ntgt5hy9 35 33 with with IN cord-280571-ntgt5hy9 35 34 laboratory laboratory NN cord-280571-ntgt5hy9 35 35 - - HYPH cord-280571-ntgt5hy9 35 36 confirmed confirm VBN cord-280571-ntgt5hy9 35 37 influenza influenza NN cord-280571-ntgt5hy9 35 38 [ [ -LRB- cord-280571-ntgt5hy9 35 39 11 11 CD cord-280571-ntgt5hy9 35 40 ] ] -RRB- cord-280571-ntgt5hy9 35 41 . . . cord-280571-ntgt5hy9 36 1 Therefore therefore RB cord-280571-ntgt5hy9 36 2 , , , cord-280571-ntgt5hy9 36 3 establishing establish VBG cord-280571-ntgt5hy9 36 4 the the DT cord-280571-ntgt5hy9 36 5 viral viral JJ cord-280571-ntgt5hy9 36 6 etiological etiological JJ cord-280571-ntgt5hy9 36 7 characteristics characteristic NNS cord-280571-ntgt5hy9 36 8 of of IN cord-280571-ntgt5hy9 36 9 the the DT cord-280571-ntgt5hy9 36 10 illness illness NN cord-280571-ntgt5hy9 36 11 is be VBZ cord-280571-ntgt5hy9 36 12 often often RB cord-280571-ntgt5hy9 36 13 highly highly RB cord-280571-ntgt5hy9 36 14 dependent dependent JJ cord-280571-ntgt5hy9 36 15 on on IN cord-280571-ntgt5hy9 36 16 accurate accurate JJ cord-280571-ntgt5hy9 36 17 diagnostic diagnostic JJ cord-280571-ntgt5hy9 36 18 testing testing NN cord-280571-ntgt5hy9 36 19 . . . cord-280571-ntgt5hy9 37 1 In in IN cord-280571-ntgt5hy9 37 2 addition addition NN cord-280571-ntgt5hy9 37 3 , , , cord-280571-ntgt5hy9 37 4 new new JJ cord-280571-ntgt5hy9 37 5 therapeutic therapeutic JJ cord-280571-ntgt5hy9 37 6 agents agent NNS cord-280571-ntgt5hy9 37 7 for for IN cord-280571-ntgt5hy9 37 8 respiratory respiratory JJ cord-280571-ntgt5hy9 37 9 viruses virus NNS cord-280571-ntgt5hy9 37 10 are be VBP cord-280571-ntgt5hy9 37 11 in in IN cord-280571-ntgt5hy9 37 12 development development NN cord-280571-ntgt5hy9 37 13 , , , cord-280571-ntgt5hy9 37 14 and and CC cord-280571-ntgt5hy9 37 15 clinical clinical JJ cord-280571-ntgt5hy9 37 16 trials trial NNS cord-280571-ntgt5hy9 37 17 for for IN cord-280571-ntgt5hy9 37 18 these these DT cord-280571-ntgt5hy9 37 19 agents agent NNS cord-280571-ntgt5hy9 37 20 will will MD cord-280571-ntgt5hy9 37 21 need need VB cord-280571-ntgt5hy9 37 22 rapid rapid JJ cord-280571-ntgt5hy9 37 23 diagnostics diagnostic NNS cord-280571-ntgt5hy9 37 24 that that WDT cord-280571-ntgt5hy9 37 25 detect detect VBP cord-280571-ntgt5hy9 37 26 a a DT cord-280571-ntgt5hy9 37 27 broad broad JJ cord-280571-ntgt5hy9 37 28 range range NN cord-280571-ntgt5hy9 37 29 of of IN cord-280571-ntgt5hy9 37 30 viral viral JJ cord-280571-ntgt5hy9 37 31 pathogens pathogen NNS cord-280571-ntgt5hy9 37 32 . . . cord-280571-ntgt5hy9 38 1 Once once IN cord-280571-ntgt5hy9 38 2 these these DT cord-280571-ntgt5hy9 38 3 new new JJ cord-280571-ntgt5hy9 38 4 drugs drug NNS cord-280571-ntgt5hy9 38 5 are be VBP cord-280571-ntgt5hy9 38 6 approved approve VBN cord-280571-ntgt5hy9 38 7 , , , cord-280571-ntgt5hy9 38 8 clinical clinical JJ cord-280571-ntgt5hy9 38 9 laboratories laboratory NNS cord-280571-ntgt5hy9 38 10 will will MD cord-280571-ntgt5hy9 38 11 need need VB cord-280571-ntgt5hy9 38 12 the the DT cord-280571-ntgt5hy9 38 13 tools tool NNS cord-280571-ntgt5hy9 38 14 to to TO cord-280571-ntgt5hy9 38 15 identify identify VB cord-280571-ntgt5hy9 38 16 each each DT cord-280571-ntgt5hy9 38 17 virus virus NN cord-280571-ntgt5hy9 38 18 so so IN cord-280571-ntgt5hy9 38 19 that that IN cord-280571-ntgt5hy9 38 20 appropriate appropriate JJ cord-280571-ntgt5hy9 38 21 antiviral antiviral JJ cord-280571-ntgt5hy9 38 22 therapy therapy NN cord-280571-ntgt5hy9 38 23 can can MD cord-280571-ntgt5hy9 38 24 be be VB cord-280571-ntgt5hy9 38 25 rapidly rapidly RB cord-280571-ntgt5hy9 38 26 initiated initiate VBN cord-280571-ntgt5hy9 38 27 . . . cord-280571-ntgt5hy9 39 1 In in IN cord-280571-ntgt5hy9 39 2 addition addition NN cord-280571-ntgt5hy9 39 3 , , , cord-280571-ntgt5hy9 39 4 during during IN cord-280571-ntgt5hy9 39 5 the the DT cord-280571-ntgt5hy9 39 6 first first JJ cord-280571-ntgt5hy9 39 7 weeks week NNS cord-280571-ntgt5hy9 39 8 of of IN cord-280571-ntgt5hy9 39 9 the the DT cord-280571-ntgt5hy9 39 10 2009 2009 CD cord-280571-ntgt5hy9 39 11 influenza influenza NN cord-280571-ntgt5hy9 39 12 A a DT cord-280571-ntgt5hy9 39 13 H1N1 H1N1 NNP cord-280571-ntgt5hy9 39 14 outbreak outbreak NN cord-280571-ntgt5hy9 39 15 in in IN cord-280571-ntgt5hy9 39 16 the the DT cord-280571-ntgt5hy9 39 17 spring spring NN cord-280571-ntgt5hy9 39 18 of of IN cord-280571-ntgt5hy9 39 19 2009 2009 CD cord-280571-ntgt5hy9 39 20 , , , cord-280571-ntgt5hy9 39 21 multiple multiple JJ cord-280571-ntgt5hy9 39 22 influenza influenza NN cord-280571-ntgt5hy9 39 23 viruses virus NNS cord-280571-ntgt5hy9 39 24 were be VBD cord-280571-ntgt5hy9 39 25 cocirculating cocirculate VBG cord-280571-ntgt5hy9 39 26 [ [ -LRB- cord-280571-ntgt5hy9 39 27 5 5 CD cord-280571-ntgt5hy9 39 28 ] ] -RRB- cord-280571-ntgt5hy9 39 29 . . . cord-280571-ntgt5hy9 40 1 It -PRON- PRP cord-280571-ntgt5hy9 40 2 was be VBD cord-280571-ntgt5hy9 40 3 necessary necessary JJ cord-280571-ntgt5hy9 40 4 to to TO cord-280571-ntgt5hy9 40 5 subtype subtype NN cord-280571-ntgt5hy9 40 6 influenza influenza NN cord-280571-ntgt5hy9 40 7 A a DT cord-280571-ntgt5hy9 40 8 strains strain NNS cord-280571-ntgt5hy9 40 9 to to TO cord-280571-ntgt5hy9 40 10 differentiate differentiate VB cord-280571-ntgt5hy9 40 11 seasonal seasonal JJ cord-280571-ntgt5hy9 40 12 influenza influenza NN cord-280571-ntgt5hy9 40 13 A A NNP cord-280571-ntgt5hy9 40 14 / / SYM cord-280571-ntgt5hy9 40 15 H1 H1 NNP cord-280571-ntgt5hy9 40 16 , , , cord-280571-ntgt5hy9 40 17 seasonal seasonal JJ cord-280571-ntgt5hy9 40 18 influenza influenza NN cord-280571-ntgt5hy9 40 19 A A NNP cord-280571-ntgt5hy9 40 20 / / SYM cord-280571-ntgt5hy9 40 21 H3 H3 NNP cord-280571-ntgt5hy9 40 22 , , , cord-280571-ntgt5hy9 40 23 and and CC cord-280571-ntgt5hy9 40 24 2009 2009 CD cord-280571-ntgt5hy9 40 25 influenza influenza NN cord-280571-ntgt5hy9 40 26 A a DT cord-280571-ntgt5hy9 40 27 H1N1 H1N1 NNP cord-280571-ntgt5hy9 40 28 . . . cord-280571-ntgt5hy9 41 1 Subtyping Subtyping NNP cord-280571-ntgt5hy9 41 2 is be VBZ cord-280571-ntgt5hy9 41 3 necessary necessary JJ cord-280571-ntgt5hy9 41 4 to to TO cord-280571-ntgt5hy9 41 5 provide provide VB cord-280571-ntgt5hy9 41 6 relevant relevant JJ cord-280571-ntgt5hy9 41 7 information information NN cord-280571-ntgt5hy9 41 8 needed need VBN cord-280571-ntgt5hy9 41 9 for for IN cord-280571-ntgt5hy9 41 10 appropriate appropriate JJ cord-280571-ntgt5hy9 41 11 selection selection NN cord-280571-ntgt5hy9 41 12 of of IN cord-280571-ntgt5hy9 41 13 antiviral antiviral JJ cord-280571-ntgt5hy9 41 14 therapy therapy NN cord-280571-ntgt5hy9 41 15 , , , cord-280571-ntgt5hy9 41 16 in in IN cord-280571-ntgt5hy9 41 17 particular particular JJ cord-280571-ntgt5hy9 41 18 for for IN cord-280571-ntgt5hy9 41 19 acutely acutely RB cord-280571-ntgt5hy9 41 20 ill ill JJ cord-280571-ntgt5hy9 41 21 patients patient NNS cord-280571-ntgt5hy9 41 22 . . . cord-280571-ntgt5hy9 42 1 Antiviral antiviral JJ cord-280571-ntgt5hy9 42 2 resistance resistance NN cord-280571-ntgt5hy9 42 3 testing testing NN cord-280571-ntgt5hy9 42 4 of of IN cord-280571-ntgt5hy9 42 5 influenza influenza NN cord-280571-ntgt5hy9 42 6 isolates isolate NNS cord-280571-ntgt5hy9 42 7 from from IN cord-280571-ntgt5hy9 42 8 2009 2009 CD cord-280571-ntgt5hy9 43 1 ( ( -LRB- cord-280571-ntgt5hy9 43 2 www.cdc.gov/flu www.cdc.gov/flu NNP cord-280571-ntgt5hy9 43 3 ) ) -RRB- cord-280571-ntgt5hy9 43 4 revealed reveal VBD cord-280571-ntgt5hy9 43 5 that that IN cord-280571-ntgt5hy9 43 6 the the DT cord-280571-ntgt5hy9 43 7 circulating circulate VBG cord-280571-ntgt5hy9 43 8 seasonal seasonal JJ cord-280571-ntgt5hy9 43 9 influenza influenza NN cord-280571-ntgt5hy9 43 10 A A NNP cord-280571-ntgt5hy9 43 11 / / SYM cord-280571-ntgt5hy9 43 12 H1 h1 NN cord-280571-ntgt5hy9 43 13 strains strain NNS cord-280571-ntgt5hy9 43 14 were be VBD cord-280571-ntgt5hy9 43 15 resistant resistant JJ cord-280571-ntgt5hy9 43 16 to to IN cord-280571-ntgt5hy9 43 17 oseltamivir oseltamivir FW cord-280571-ntgt5hy9 43 18 ( ( -LRB- cord-280571-ntgt5hy9 43 19 99.6 99.6 CD cord-280571-ntgt5hy9 43 20 % % NN cord-280571-ntgt5hy9 43 21 ) ) -RRB- cord-280571-ntgt5hy9 43 22 , , , cord-280571-ntgt5hy9 43 23 and and CC cord-280571-ntgt5hy9 43 24 seasonal seasonal JJ cord-280571-ntgt5hy9 43 25 influenza influenza NN cord-280571-ntgt5hy9 43 26 A A NNP cord-280571-ntgt5hy9 43 27 / / SYM cord-280571-ntgt5hy9 43 28 H3 H3 NNP cord-280571-ntgt5hy9 43 29 and and CC cord-280571-ntgt5hy9 43 30 2009 2009 CD cord-280571-ntgt5hy9 43 31 influenza influenza NN cord-280571-ntgt5hy9 44 1 A a DT cord-280571-ntgt5hy9 44 2 H1N1 H1N1 NNP cord-280571-ntgt5hy9 44 3 were be VBD cord-280571-ntgt5hy9 44 4 resistant resistant JJ cord-280571-ntgt5hy9 44 5 to to IN cord-280571-ntgt5hy9 44 6 the the DT cord-280571-ntgt5hy9 44 7 adamantanes adamantane NNS cord-280571-ntgt5hy9 44 8 ( ( -LRB- cord-280571-ntgt5hy9 44 9 100 100 CD cord-280571-ntgt5hy9 44 10 % % NN cord-280571-ntgt5hy9 44 11 ) ) -RRB- cord-280571-ntgt5hy9 44 12 . . . cord-280571-ntgt5hy9 45 1 In in IN cord-280571-ntgt5hy9 45 2 addition addition NN cord-280571-ntgt5hy9 45 3 , , , cord-280571-ntgt5hy9 45 4 several several JJ cord-280571-ntgt5hy9 45 5 patients patient NNS cord-280571-ntgt5hy9 45 6 with with IN cord-280571-ntgt5hy9 45 7 2009 2009 CD cord-280571-ntgt5hy9 45 8 influenza influenza NN cord-280571-ntgt5hy9 46 1 A a DT cord-280571-ntgt5hy9 46 2 H1N1 H1N1 NNP cord-280571-ntgt5hy9 46 3 infections infection NNS cord-280571-ntgt5hy9 46 4 developed develop VBD cord-280571-ntgt5hy9 46 5 oseltamivir oseltamivir NN cord-280571-ntgt5hy9 46 6 resistance resistance NN cord-280571-ntgt5hy9 46 7 [ [ -LRB- cord-280571-ntgt5hy9 46 8 12 12 CD cord-280571-ntgt5hy9 46 9 , , , cord-280571-ntgt5hy9 46 10 13 13 CD cord-280571-ntgt5hy9 46 11 ] ] -RRB- cord-280571-ntgt5hy9 46 12 . . . cord-280571-ntgt5hy9 47 1 Other other JJ cord-280571-ntgt5hy9 47 2 clinical clinical JJ cord-280571-ntgt5hy9 47 3 factors factor NNS cord-280571-ntgt5hy9 47 4 , , , cord-280571-ntgt5hy9 47 5 such such JJ cord-280571-ntgt5hy9 47 6 as as IN cord-280571-ntgt5hy9 47 7 the the DT cord-280571-ntgt5hy9 47 8 potential potential NN cord-280571-ntgt5hy9 47 9 for for IN cord-280571-ntgt5hy9 47 10 the the DT cord-280571-ntgt5hy9 47 11 development development NN cord-280571-ntgt5hy9 47 12 of of IN cord-280571-ntgt5hy9 47 13 more more RBR cord-280571-ntgt5hy9 47 14 severe severe JJ cord-280571-ntgt5hy9 47 15 disease disease NN cord-280571-ntgt5hy9 47 16 on on IN cord-280571-ntgt5hy9 47 17 the the DT cord-280571-ntgt5hy9 47 18 basis basis NN cord-280571-ntgt5hy9 47 19 of of IN cord-280571-ntgt5hy9 47 20 the the DT cord-280571-ntgt5hy9 47 21 virus virus NN cord-280571-ntgt5hy9 47 22 etiology etiology NN cord-280571-ntgt5hy9 47 23 , , , cord-280571-ntgt5hy9 47 24 may may MD cord-280571-ntgt5hy9 47 25 need need VB cord-280571-ntgt5hy9 47 26 to to TO cord-280571-ntgt5hy9 47 27 be be VB cord-280571-ntgt5hy9 47 28 considered consider VBN cord-280571-ntgt5hy9 47 29 in in IN cord-280571-ntgt5hy9 47 30 the the DT cord-280571-ntgt5hy9 47 31 management management NN cord-280571-ntgt5hy9 47 32 of of IN cord-280571-ntgt5hy9 47 33 certain certain JJ cord-280571-ntgt5hy9 47 34 patients patient NNS cord-280571-ntgt5hy9 47 35 . . . cord-280571-ntgt5hy9 48 1 For for IN cord-280571-ntgt5hy9 48 2 example example NN cord-280571-ntgt5hy9 48 3 , , , cord-280571-ntgt5hy9 48 4 studies study NNS cord-280571-ntgt5hy9 48 5 from from IN cord-280571-ntgt5hy9 48 6 our -PRON- PRP$ cord-280571-ntgt5hy9 48 7 laboratory laboratory NN cord-280571-ntgt5hy9 48 8 have have VBP cord-280571-ntgt5hy9 48 9 revealed reveal VBN cord-280571-ntgt5hy9 48 10 that that IN cord-280571-ntgt5hy9 48 11 children child NNS cord-280571-ntgt5hy9 48 12 with with IN cord-280571-ntgt5hy9 48 13 hMPV hmpv NN cord-280571-ntgt5hy9 48 14 infections infection NNS cord-280571-ntgt5hy9 48 15 have have VBP cord-280571-ntgt5hy9 48 16 a a DT cord-280571-ntgt5hy9 48 17 higher high JJR cord-280571-ntgt5hy9 48 18 incidence incidence NN cord-280571-ntgt5hy9 48 19 of of IN cord-280571-ntgt5hy9 48 20 admission admission NN cord-280571-ntgt5hy9 48 21 to to IN cord-280571-ntgt5hy9 48 22 an an DT cord-280571-ntgt5hy9 48 23 intensive intensive JJ cord-280571-ntgt5hy9 48 24 care care NN cord-280571-ntgt5hy9 48 25 unit unit NN cord-280571-ntgt5hy9 48 26 and and CC cord-280571-ntgt5hy9 48 27 more more RBR cord-280571-ntgt5hy9 48 28 often often RB cord-280571-ntgt5hy9 48 29 require require VBP cord-280571-ntgt5hy9 48 30 mechanical mechanical JJ cord-280571-ntgt5hy9 48 31 ventilation ventilation NN cord-280571-ntgt5hy9 48 32 than than IN cord-280571-ntgt5hy9 48 33 children child NNS cord-280571-ntgt5hy9 48 34 with with IN cord-280571-ntgt5hy9 48 35 RSV RSV NNP cord-280571-ntgt5hy9 48 36 infections infection NNS cord-280571-ntgt5hy9 48 37 [ [ -LRB- cord-280571-ntgt5hy9 48 38 14 14 CD cord-280571-ntgt5hy9 48 39 , , , cord-280571-ntgt5hy9 48 40 15 15 CD cord-280571-ntgt5hy9 48 41 ] ] -RRB- cord-280571-ntgt5hy9 48 42 . . . cord-280571-ntgt5hy9 49 1 Especially especially RB cord-280571-ntgt5hy9 49 2 in in IN cord-280571-ntgt5hy9 49 3 the the DT cord-280571-ntgt5hy9 49 4 treatment treatment NN cord-280571-ntgt5hy9 49 5 of of IN cord-280571-ntgt5hy9 49 6 inpatients inpatient NNS cord-280571-ntgt5hy9 49 7 , , , cord-280571-ntgt5hy9 49 8 the the DT cord-280571-ntgt5hy9 49 9 costs cost NNS cord-280571-ntgt5hy9 49 10 of of IN cord-280571-ntgt5hy9 49 11 rapid rapid JJ cord-280571-ntgt5hy9 49 12 viral viral JJ cord-280571-ntgt5hy9 49 13 diagnostics diagnostic NNS cord-280571-ntgt5hy9 49 14 can can MD cord-280571-ntgt5hy9 49 15 be be VB cord-280571-ntgt5hy9 49 16 offset offset VBN cord-280571-ntgt5hy9 49 17 by by IN cord-280571-ntgt5hy9 49 18 the the DT cord-280571-ntgt5hy9 49 19 improvement improvement NN cord-280571-ntgt5hy9 49 20 in in IN cord-280571-ntgt5hy9 49 21 patient patient JJ cord-280571-ntgt5hy9 49 22 care care NN cord-280571-ntgt5hy9 49 23 and and CC cord-280571-ntgt5hy9 49 24 financial financial JJ cord-280571-ntgt5hy9 49 25 outcomes outcome NNS cord-280571-ntgt5hy9 49 26 [ [ -LRB- cord-280571-ntgt5hy9 49 27 16 16 CD cord-280571-ntgt5hy9 49 28 ] ] -RRB- cord-280571-ntgt5hy9 50 1 [ [ -LRB- cord-280571-ntgt5hy9 50 2 17 17 CD cord-280571-ntgt5hy9 50 3 ] ] -RRB- cord-280571-ntgt5hy9 50 4 [ [ -LRB- cord-280571-ntgt5hy9 50 5 18 18 CD cord-280571-ntgt5hy9 50 6 ] ] -RRB- cord-280571-ntgt5hy9 50 7 [ [ -LRB- cord-280571-ntgt5hy9 50 8 19 19 CD cord-280571-ntgt5hy9 50 9 ] ] -RRB- cord-280571-ntgt5hy9 50 10 . . . cord-280571-ntgt5hy9 51 1 Hendrickson Hendrickson NNP cord-280571-ntgt5hy9 51 2 et et NNP cord-280571-ntgt5hy9 51 3 al al NNP cord-280571-ntgt5hy9 51 4 showed show VBD cord-280571-ntgt5hy9 51 5 that that IN cord-280571-ntgt5hy9 51 6 rapid rapid JJ cord-280571-ntgt5hy9 51 7 respiratory respiratory JJ cord-280571-ntgt5hy9 51 8 virus virus NN cord-280571-ntgt5hy9 51 9 diagnosis diagnosis NN cord-280571-ntgt5hy9 51 10 can can MD cord-280571-ntgt5hy9 51 11 lead lead VB cord-280571-ntgt5hy9 51 12 to to IN cord-280571-ntgt5hy9 51 13 benefits benefit NNS cord-280571-ntgt5hy9 51 14 in in IN cord-280571-ntgt5hy9 51 15 several several JJ cord-280571-ntgt5hy9 51 16 areas area NNS cord-280571-ntgt5hy9 51 17 , , , cord-280571-ntgt5hy9 51 18 including include VBG cord-280571-ntgt5hy9 51 19 up up IN cord-280571-ntgt5hy9 51 20 to to IN cord-280571-ntgt5hy9 51 21 a a DT cord-280571-ntgt5hy9 51 22 50 50 CD cord-280571-ntgt5hy9 51 23 % % NN cord-280571-ntgt5hy9 51 24 reduction reduction NN cord-280571-ntgt5hy9 51 25 in in IN cord-280571-ntgt5hy9 51 26 hospital hospital NN cord-280571-ntgt5hy9 51 27 days day NNS cord-280571-ntgt5hy9 51 28 , , , cord-280571-ntgt5hy9 51 29 30 30 CD cord-280571-ntgt5hy9 51 30 % % NN cord-280571-ntgt5hy9 51 31 reduction reduction NN cord-280571-ntgt5hy9 51 32 in in IN cord-280571-ntgt5hy9 51 33 antibiotic antibiotic JJ cord-280571-ntgt5hy9 51 34 use use NN cord-280571-ntgt5hy9 51 35 , , , cord-280571-ntgt5hy9 51 36 and and CC cord-280571-ntgt5hy9 51 37 20 20 CD cord-280571-ntgt5hy9 51 38 % % NN cord-280571-ntgt5hy9 51 39 reduction reduction NN cord-280571-ntgt5hy9 51 40 in in IN cord-280571-ntgt5hy9 51 41 unnecessary unnecessary JJ cord-280571-ntgt5hy9 51 42 diagnostic diagnostic JJ cord-280571-ntgt5hy9 51 43 tests test NNS cord-280571-ntgt5hy9 51 44 and and CC cord-280571-ntgt5hy9 51 45 procedures procedure NNS cord-280571-ntgt5hy9 51 46 [ [ -LRB- cord-280571-ntgt5hy9 51 47 16 16 CD cord-280571-ntgt5hy9 51 48 ] ] -RRB- cord-280571-ntgt5hy9 51 49 . . . cord-280571-ntgt5hy9 52 1 The the DT cord-280571-ntgt5hy9 52 2 burden burden NN cord-280571-ntgt5hy9 52 3 of of IN cord-280571-ntgt5hy9 52 4 nosocomial nosocomial JJ cord-280571-ntgt5hy9 52 5 influenza influenza NN cord-280571-ntgt5hy9 52 6 can can MD cord-280571-ntgt5hy9 52 7 be be VB cord-280571-ntgt5hy9 52 8 high high JJ cord-280571-ntgt5hy9 52 9 , , , cord-280571-ntgt5hy9 52 10 incurring incur VBG cord-280571-ntgt5hy9 52 11 additional additional JJ cord-280571-ntgt5hy9 52 12 costs cost NNS cord-280571-ntgt5hy9 52 13 for for IN cord-280571-ntgt5hy9 52 14 diagnostic diagnostic JJ cord-280571-ntgt5hy9 52 15 tests test NNS cord-280571-ntgt5hy9 52 16 , , , cord-280571-ntgt5hy9 52 17 increased increase VBN cord-280571-ntgt5hy9 52 18 morbidity morbidity NN cord-280571-ntgt5hy9 52 19 , , , cord-280571-ntgt5hy9 52 20 and and CC cord-280571-ntgt5hy9 52 21 extended extended JJ cord-280571-ntgt5hy9 52 22 hospitalization hospitalization NN cord-280571-ntgt5hy9 52 23 [ [ -LRB- cord-280571-ntgt5hy9 52 24 17 17 CD cord-280571-ntgt5hy9 52 25 , , , cord-280571-ntgt5hy9 52 26 18 18 CD cord-280571-ntgt5hy9 52 27 ] ] -RRB- cord-280571-ntgt5hy9 52 28 . . . cord-280571-ntgt5hy9 53 1 Therefore therefore RB cord-280571-ntgt5hy9 53 2 , , , cord-280571-ntgt5hy9 53 3 rapid rapid JJ cord-280571-ntgt5hy9 53 4 diagnostic diagnostic JJ cord-280571-ntgt5hy9 53 5 tests test NNS cord-280571-ntgt5hy9 53 6 are be VBP cord-280571-ntgt5hy9 53 7 needed need VBN cord-280571-ntgt5hy9 53 8 to to TO cord-280571-ntgt5hy9 53 9 identify identify VB cord-280571-ntgt5hy9 53 10 patients patient NNS cord-280571-ntgt5hy9 53 11 with with IN cord-280571-ntgt5hy9 53 12 influenza influenza NN cord-280571-ntgt5hy9 53 13 at at IN cord-280571-ntgt5hy9 53 14 admission admission NN cord-280571-ntgt5hy9 53 15 , , , cord-280571-ntgt5hy9 53 16 in in IN cord-280571-ntgt5hy9 53 17 order order NN cord-280571-ntgt5hy9 53 18 to to TO cord-280571-ntgt5hy9 53 19 prevent prevent VB cord-280571-ntgt5hy9 53 20 nosocomial nosocomial JJ cord-280571-ntgt5hy9 53 21 transmission transmission NN cord-280571-ntgt5hy9 53 22 by by IN cord-280571-ntgt5hy9 53 23 facilitating facilitate VBG cord-280571-ntgt5hy9 53 24 isolation isolation NN cord-280571-ntgt5hy9 53 25 and and CC cord-280571-ntgt5hy9 53 26 cohorting cohorting NN cord-280571-ntgt5hy9 53 27 decisions decision NNS cord-280571-ntgt5hy9 53 28 [ [ -LRB- cord-280571-ntgt5hy9 53 29 18 18 CD cord-280571-ntgt5hy9 53 30 ] ] -RRB- cord-280571-ntgt5hy9 53 31 . . . cord-280571-ntgt5hy9 54 1 Studies study NNS cord-280571-ntgt5hy9 54 2 have have VBP cord-280571-ntgt5hy9 54 3 documented document VBN cord-280571-ntgt5hy9 54 4 substantial substantial JJ cord-280571-ntgt5hy9 54 5 nosocomial nosocomial JJ cord-280571-ntgt5hy9 54 6 transmission transmission NN cord-280571-ntgt5hy9 54 7 of of IN cord-280571-ntgt5hy9 54 8 hMPV hmpv NN cord-280571-ntgt5hy9 54 9 in in IN cord-280571-ntgt5hy9 54 10 pediatric pediatric JJ cord-280571-ntgt5hy9 54 11 units unit NNS cord-280571-ntgt5hy9 54 12 [ [ -LRB- cord-280571-ntgt5hy9 54 13 20 20 CD cord-280571-ntgt5hy9 54 14 ] ] -RRB- cord-280571-ntgt5hy9 54 15 , , , cord-280571-ntgt5hy9 54 16 as as RB cord-280571-ntgt5hy9 54 17 well well RB cord-280571-ntgt5hy9 54 18 as as IN cord-280571-ntgt5hy9 54 19 in in IN cord-280571-ntgt5hy9 54 20 chronic chronic JJ cord-280571-ntgt5hy9 54 21 care care NN cord-280571-ntgt5hy9 54 22 facilities facility NNS cord-280571-ntgt5hy9 54 23 [ [ -LRB- cord-280571-ntgt5hy9 54 24 21 21 CD cord-280571-ntgt5hy9 54 25 ] ] -RRB- cord-280571-ntgt5hy9 54 26 , , , cord-280571-ntgt5hy9 54 27 similar similar JJ cord-280571-ntgt5hy9 54 28 to to IN cord-280571-ntgt5hy9 54 29 what what WP cord-280571-ntgt5hy9 54 30 is be VBZ cord-280571-ntgt5hy9 54 31 seen see VBN cord-280571-ntgt5hy9 54 32 with with IN cord-280571-ntgt5hy9 54 33 RSV RSV NNP cord-280571-ntgt5hy9 54 34 . . . cord-280571-ntgt5hy9 55 1 During during IN cord-280571-ntgt5hy9 55 2 the the DT cord-280571-ntgt5hy9 55 3 height height NN cord-280571-ntgt5hy9 55 4 of of IN cord-280571-ntgt5hy9 55 5 RSV RSV NNP cord-280571-ntgt5hy9 55 6 season season NN cord-280571-ntgt5hy9 55 7 , , , cord-280571-ntgt5hy9 55 8 many many JJ cord-280571-ntgt5hy9 55 9 institutions institution NNS cord-280571-ntgt5hy9 55 10 must must MD cord-280571-ntgt5hy9 55 11 cohort cohort VB cord-280571-ntgt5hy9 55 12 RSV RSV NNP cord-280571-ntgt5hy9 55 13 - - HYPH cord-280571-ntgt5hy9 55 14 positive positive JJ cord-280571-ntgt5hy9 55 15 children child NNS cord-280571-ntgt5hy9 55 16 because because IN cord-280571-ntgt5hy9 55 17 of of IN cord-280571-ntgt5hy9 55 18 a a DT cord-280571-ntgt5hy9 55 19 lack lack NN cord-280571-ntgt5hy9 55 20 of of IN cord-280571-ntgt5hy9 55 21 private private JJ cord-280571-ntgt5hy9 55 22 rooms room NNS cord-280571-ntgt5hy9 55 23 . . . cord-280571-ntgt5hy9 56 1 However however RB cord-280571-ntgt5hy9 56 2 , , , cord-280571-ntgt5hy9 56 3 dual dual JJ cord-280571-ntgt5hy9 56 4 infections infection NNS cord-280571-ntgt5hy9 56 5 with with IN cord-280571-ntgt5hy9 56 6 RSV RSV NNP cord-280571-ntgt5hy9 56 7 and and CC cord-280571-ntgt5hy9 56 8 hMPV hmpv NN cord-280571-ntgt5hy9 56 9 do do VBP cord-280571-ntgt5hy9 56 10 occur occur VB cord-280571-ntgt5hy9 56 11 . . . cord-280571-ntgt5hy9 57 1 Limiting limit VBG cord-280571-ntgt5hy9 57 2 diagnostics diagnostic NNS cord-280571-ntgt5hy9 57 3 to to IN cord-280571-ntgt5hy9 57 4 RSV RSV NNP cord-280571-ntgt5hy9 57 5 alone alone RB cord-280571-ntgt5hy9 57 6 in in IN cord-280571-ntgt5hy9 57 7 a a DT cord-280571-ntgt5hy9 57 8 cohorting cohorting NN cord-280571-ntgt5hy9 57 9 scenario scenario NN cord-280571-ntgt5hy9 57 10 could could MD cord-280571-ntgt5hy9 57 11 put put VB cord-280571-ntgt5hy9 57 12 other other JJ cord-280571-ntgt5hy9 57 13 seriously seriously RB cord-280571-ntgt5hy9 57 14 ill ill JJ cord-280571-ntgt5hy9 57 15 children child NNS cord-280571-ntgt5hy9 57 16 at at IN cord-280571-ntgt5hy9 57 17 risk risk NN cord-280571-ntgt5hy9 57 18 for for IN cord-280571-ntgt5hy9 57 19 acquisition acquisition NN cord-280571-ntgt5hy9 57 20 of of IN cord-280571-ntgt5hy9 57 21 a a DT cord-280571-ntgt5hy9 57 22 second second JJ cord-280571-ntgt5hy9 57 23 viral viral JJ cord-280571-ntgt5hy9 57 24 infection infection NN cord-280571-ntgt5hy9 57 25 with with IN cord-280571-ntgt5hy9 57 26 hMPV hmpv NN cord-280571-ntgt5hy9 57 27 . . . cord-280571-ntgt5hy9 58 1 The the DT cord-280571-ntgt5hy9 58 2 meaning meaning NN cord-280571-ntgt5hy9 58 3 of of IN cord-280571-ntgt5hy9 58 4 mixed mixed JJ cord-280571-ntgt5hy9 58 5 viral viral JJ cord-280571-ntgt5hy9 58 6 infections infection NNS cord-280571-ntgt5hy9 58 7 can can MD cord-280571-ntgt5hy9 58 8 be be VB cord-280571-ntgt5hy9 58 9 defined define VBN cord-280571-ntgt5hy9 58 10 only only RB cord-280571-ntgt5hy9 58 11 if if IN cord-280571-ntgt5hy9 58 12 testing testing NN cord-280571-ntgt5hy9 58 13 is be VBZ cord-280571-ntgt5hy9 58 14 comprehensive comprehensive JJ cord-280571-ntgt5hy9 58 15 . . . cord-280571-ntgt5hy9 59 1 Broad broad JJ cord-280571-ntgt5hy9 59 2 test test NN cord-280571-ntgt5hy9 59 3 panels panel NNS cord-280571-ntgt5hy9 59 4 also also RB cord-280571-ntgt5hy9 59 5 allow allow VBP cord-280571-ntgt5hy9 59 6 for for IN cord-280571-ntgt5hy9 59 7 monitoring monitor VBG cord-280571-ntgt5hy9 59 8 the the DT cord-280571-ntgt5hy9 59 9 epidemiologic epidemiologic JJ cord-280571-ntgt5hy9 59 10 patterns pattern NNS cord-280571-ntgt5hy9 59 11 of of IN cord-280571-ntgt5hy9 59 12 respiratory respiratory JJ cord-280571-ntgt5hy9 59 13 disease disease NN cord-280571-ntgt5hy9 59 14 and and CC cord-280571-ntgt5hy9 59 15 for for IN cord-280571-ntgt5hy9 59 16 identifying identify VBG cord-280571-ntgt5hy9 59 17 new new JJ cord-280571-ntgt5hy9 59 18 or or CC cord-280571-ntgt5hy9 59 19 reemerging reemerge VBG cord-280571-ntgt5hy9 59 20 pathogens pathogen NNS cord-280571-ntgt5hy9 59 21 . . . cord-280571-ntgt5hy9 60 1 Finally finally RB cord-280571-ntgt5hy9 60 2 , , , cord-280571-ntgt5hy9 60 3 the the DT cord-280571-ntgt5hy9 60 4 identification identification NN cord-280571-ntgt5hy9 60 5 of of IN cord-280571-ntgt5hy9 60 6 the the DT cord-280571-ntgt5hy9 60 7 exact exact JJ cord-280571-ntgt5hy9 60 8 respiratory respiratory JJ cord-280571-ntgt5hy9 60 9 virus virus NN cord-280571-ntgt5hy9 60 10 is be VBZ cord-280571-ntgt5hy9 60 11 essential essential JJ cord-280571-ntgt5hy9 60 12 for for IN cord-280571-ntgt5hy9 60 13 the the DT cord-280571-ntgt5hy9 60 14 accurate accurate JJ cord-280571-ntgt5hy9 60 15 assessment assessment NN cord-280571-ntgt5hy9 60 16 of of IN cord-280571-ntgt5hy9 60 17 the the DT cord-280571-ntgt5hy9 60 18 efficacy efficacy NN cord-280571-ntgt5hy9 60 19 of of IN cord-280571-ntgt5hy9 60 20 vaccines vaccine NNS cord-280571-ntgt5hy9 60 21 . . . cord-280571-ntgt5hy9 61 1 The the DT cord-280571-ntgt5hy9 61 2 costs cost NNS cord-280571-ntgt5hy9 61 3 for for IN cord-280571-ntgt5hy9 61 4 testing test VBG cord-280571-ntgt5hy9 61 5 using use VBG cord-280571-ntgt5hy9 61 6 FDA FDA NNP cord-280571-ntgt5hy9 61 7 - - HYPH cord-280571-ntgt5hy9 61 8 approved approve VBN cord-280571-ntgt5hy9 61 9 / / SYM cord-280571-ntgt5hy9 61 10 cleared clear VBN cord-280571-ntgt5hy9 61 11 NAATs NAATs NNP cord-280571-ntgt5hy9 61 12 are be VBP cord-280571-ntgt5hy9 61 13 highly highly RB cord-280571-ntgt5hy9 61 14 variable variable JJ cord-280571-ntgt5hy9 61 15 and and CC cord-280571-ntgt5hy9 61 16 can can MD cord-280571-ntgt5hy9 61 17 range range VB cord-280571-ntgt5hy9 61 18 from from IN cord-280571-ntgt5hy9 61 19 approximately approximately RB cord-280571-ntgt5hy9 61 20 $ $ $ cord-280571-ntgt5hy9 61 21 30 30 CD cord-280571-ntgt5hy9 61 22 to to IN cord-280571-ntgt5hy9 61 23 .$200 .$200 . cord-280571-ntgt5hy9 62 1 per per IN cord-280571-ntgt5hy9 62 2 test test NN cord-280571-ntgt5hy9 62 3 . . . cord-280571-ntgt5hy9 63 1 Factors factor NNS cord-280571-ntgt5hy9 63 2 that that WDT cord-280571-ntgt5hy9 63 3 determine determine VBP cord-280571-ntgt5hy9 63 4 test test NN cord-280571-ntgt5hy9 63 5 cost cost NN cord-280571-ntgt5hy9 63 6 include include VBP cord-280571-ntgt5hy9 63 7 test test NN cord-280571-ntgt5hy9 63 8 volume volume NN cord-280571-ntgt5hy9 63 9 , , , cord-280571-ntgt5hy9 63 10 the the DT cord-280571-ntgt5hy9 63 11 price price NN cord-280571-ntgt5hy9 63 12 of of IN cord-280571-ntgt5hy9 63 13 the the DT cord-280571-ntgt5hy9 63 14 test test NN cord-280571-ntgt5hy9 63 15 kits kit NNS cord-280571-ntgt5hy9 63 16 , , , cord-280571-ntgt5hy9 63 17 the the DT cord-280571-ntgt5hy9 63 18 number number NN cord-280571-ntgt5hy9 63 19 of of IN cord-280571-ntgt5hy9 63 20 tests test NNS cord-280571-ntgt5hy9 63 21 per per IN cord-280571-ntgt5hy9 63 22 kit kit NN cord-280571-ntgt5hy9 63 23 , , , cord-280571-ntgt5hy9 63 24 size size NN cord-280571-ntgt5hy9 63 25 of of IN cord-280571-ntgt5hy9 63 26 the the DT cord-280571-ntgt5hy9 63 27 testing testing NN cord-280571-ntgt5hy9 63 28 run run NN cord-280571-ntgt5hy9 63 29 , , , cord-280571-ntgt5hy9 63 30 the the DT cord-280571-ntgt5hy9 63 31 number number NN cord-280571-ntgt5hy9 63 32 of of IN cord-280571-ntgt5hy9 63 33 controls control NNS cord-280571-ntgt5hy9 63 34 required require VBN cord-280571-ntgt5hy9 63 35 per per IN cord-280571-ntgt5hy9 63 36 testing testing NN cord-280571-ntgt5hy9 63 37 run run NN cord-280571-ntgt5hy9 63 38 , , , cord-280571-ntgt5hy9 63 39 and and CC cord-280571-ntgt5hy9 63 40 the the DT cord-280571-ntgt5hy9 63 41 type type NN cord-280571-ntgt5hy9 63 42 and and CC cord-280571-ntgt5hy9 63 43 amount amount NN cord-280571-ntgt5hy9 63 44 of of IN cord-280571-ntgt5hy9 63 45 ancillary ancillary JJ cord-280571-ntgt5hy9 63 46 supplies supply NNS cord-280571-ntgt5hy9 63 47 . . . cord-280571-ntgt5hy9 64 1 Often often RB cord-280571-ntgt5hy9 64 2 FDA FDA NNP cord-280571-ntgt5hy9 64 3 - - HYPH cord-280571-ntgt5hy9 64 4 approved/ approved/ NNP cord-280571-ntgt5hy9 64 5 cleared clear VBN cord-280571-ntgt5hy9 64 6 kits kit NNS cord-280571-ntgt5hy9 64 7 do do VBP cord-280571-ntgt5hy9 64 8 not not RB cord-280571-ntgt5hy9 64 9 contain contain VB cord-280571-ntgt5hy9 64 10 nucleic nucleic JJ cord-280571-ntgt5hy9 64 11 acid acid NN cord-280571-ntgt5hy9 64 12 extraction extraction NN cord-280571-ntgt5hy9 64 13 reagents reagent NNS cord-280571-ntgt5hy9 64 14 , , , cord-280571-ntgt5hy9 64 15 so so IN cord-280571-ntgt5hy9 64 16 additional additional JJ cord-280571-ntgt5hy9 64 17 equipment equipment NN cord-280571-ntgt5hy9 64 18 and and CC cord-280571-ntgt5hy9 64 19 reagents reagent NNS cord-280571-ntgt5hy9 64 20 are be VBP cord-280571-ntgt5hy9 64 21 necessary necessary JJ cord-280571-ntgt5hy9 64 22 and and CC cord-280571-ntgt5hy9 64 23 can can MD cord-280571-ntgt5hy9 64 24 add add VB cord-280571-ntgt5hy9 64 25 $ $ $ cord-280571-ntgt5hy9 64 26 3-$15 3-$15 CD cord-280571-ntgt5hy9 64 27 per per IN cord-280571-ntgt5hy9 64 28 test test NN cord-280571-ntgt5hy9 64 29 . . . cord-280571-ntgt5hy9 65 1 Batch batch JJ cord-280571-ntgt5hy9 65 2 testing testing NN cord-280571-ntgt5hy9 65 3 of of IN cord-280571-ntgt5hy9 65 4 samples sample NNS cord-280571-ntgt5hy9 65 5 may may MD cord-280571-ntgt5hy9 65 6 reduce reduce VB cord-280571-ntgt5hy9 65 7 the the DT cord-280571-ntgt5hy9 65 8 cost cost NN cord-280571-ntgt5hy9 65 9 per per IN cord-280571-ntgt5hy9 65 10 test test NN cord-280571-ntgt5hy9 65 11 ; ; : cord-280571-ntgt5hy9 65 12 however however RB cord-280571-ntgt5hy9 65 13 , , , cord-280571-ntgt5hy9 65 14 often often RB cord-280571-ntgt5hy9 65 15 batching batch VBG cord-280571-ntgt5hy9 65 16 is be VBZ cord-280571-ntgt5hy9 65 17 not not RB cord-280571-ntgt5hy9 65 18 practical practical JJ cord-280571-ntgt5hy9 65 19 if if IN cord-280571-ntgt5hy9 65 20 the the DT cord-280571-ntgt5hy9 65 21 time time NN cord-280571-ntgt5hy9 65 22 to to TO cord-280571-ntgt5hy9 65 23 result result VB cord-280571-ntgt5hy9 65 24 is be VBZ cord-280571-ntgt5hy9 65 25 delayed delay VBN cord-280571-ntgt5hy9 65 26 beyond beyond IN cord-280571-ntgt5hy9 65 27 a a DT cord-280571-ntgt5hy9 65 28 period period NN cord-280571-ntgt5hy9 65 29 that that WDT cord-280571-ntgt5hy9 65 30 would would MD cord-280571-ntgt5hy9 65 31 affect affect VB cord-280571-ntgt5hy9 65 32 either either CC cord-280571-ntgt5hy9 65 33 clinical clinical JJ cord-280571-ntgt5hy9 65 34 management management NN cord-280571-ntgt5hy9 65 35 or or CC cord-280571-ntgt5hy9 65 36 infection infection NN cord-280571-ntgt5hy9 65 37 control control NN cord-280571-ntgt5hy9 65 38 practices practice NNS cord-280571-ntgt5hy9 65 39 . . . cord-280571-ntgt5hy9 66 1 Instrumentation instrumentation NN cord-280571-ntgt5hy9 66 2 costs cost NNS cord-280571-ntgt5hy9 66 3 for for IN cord-280571-ntgt5hy9 66 4 molecular molecular JJ cord-280571-ntgt5hy9 66 5 tests test NNS cord-280571-ntgt5hy9 66 6 can can MD cord-280571-ntgt5hy9 66 7 be be VB cord-280571-ntgt5hy9 66 8 substantial substantial JJ cord-280571-ntgt5hy9 66 9 , , , cord-280571-ntgt5hy9 66 10 with with IN cord-280571-ntgt5hy9 66 11 real real JJ cord-280571-ntgt5hy9 66 12 - - HYPH cord-280571-ntgt5hy9 66 13 time time NN cord-280571-ntgt5hy9 66 14 instrumentation instrumentation NN cord-280571-ntgt5hy9 66 15 costing cost VBG cord-280571-ntgt5hy9 66 16 on on IN cord-280571-ntgt5hy9 66 17 average average JJ cord-280571-ntgt5hy9 66 18 $ $ $ cord-280571-ntgt5hy9 66 19 35,000-$85,000 35,000-$85,000 CD cord-280571-ntgt5hy9 66 20 per per IN cord-280571-ntgt5hy9 66 21 instrument instrument NN cord-280571-ntgt5hy9 66 22 , , , cord-280571-ntgt5hy9 66 23 and and CC cord-280571-ntgt5hy9 66 24 higher high JJR cord-280571-ntgt5hy9 66 25 volume volume NN cord-280571-ntgt5hy9 66 26 laboratories laboratory NNS cord-280571-ntgt5hy9 66 27 may may MD cord-280571-ntgt5hy9 66 28 require require VB cord-280571-ntgt5hy9 66 29 multiple multiple JJ cord-280571-ntgt5hy9 66 30 instruments instrument NNS cord-280571-ntgt5hy9 66 31 . . . cord-280571-ntgt5hy9 67 1 Laboratories laboratory NNS cord-280571-ntgt5hy9 67 2 must must MD cord-280571-ntgt5hy9 67 3 also also RB cord-280571-ntgt5hy9 67 4 calculate calculate VB cord-280571-ntgt5hy9 67 5 the the DT cord-280571-ntgt5hy9 67 6 cost cost NN cord-280571-ntgt5hy9 67 7 for for IN cord-280571-ntgt5hy9 67 8 technical technical JJ cord-280571-ntgt5hy9 67 9 time time NN cord-280571-ntgt5hy9 67 10 , , , cord-280571-ntgt5hy9 67 11 which which WDT cord-280571-ntgt5hy9 67 12 is be VBZ cord-280571-ntgt5hy9 67 13 again again RB cord-280571-ntgt5hy9 67 14 highly highly RB cord-280571-ntgt5hy9 67 15 variable variable JJ cord-280571-ntgt5hy9 67 16 depending depend VBG cord-280571-ntgt5hy9 67 17 on on IN cord-280571-ntgt5hy9 67 18 the the DT cord-280571-ntgt5hy9 67 19 test test NN cord-280571-ntgt5hy9 67 20 complexity complexity NN cord-280571-ntgt5hy9 67 21 and and CC cord-280571-ntgt5hy9 67 22 run run NN cord-280571-ntgt5hy9 67 23 size size NN cord-280571-ntgt5hy9 67 24 . . . cord-280571-ntgt5hy9 68 1 Finally finally RB cord-280571-ntgt5hy9 68 2 , , , cord-280571-ntgt5hy9 68 3 the the DT cord-280571-ntgt5hy9 68 4 costs cost NNS cord-280571-ntgt5hy9 68 5 for for IN cord-280571-ntgt5hy9 68 6 quality quality NN cord-280571-ntgt5hy9 68 7 control control NN cord-280571-ntgt5hy9 68 8 , , , cord-280571-ntgt5hy9 68 9 proficiency proficiency NN cord-280571-ntgt5hy9 68 10 testing testing NN cord-280571-ntgt5hy9 68 11 , , , cord-280571-ntgt5hy9 68 12 and and CC cord-280571-ntgt5hy9 68 13 competency competency NN cord-280571-ntgt5hy9 68 14 assessment assessment NN cord-280571-ntgt5hy9 68 15 all all DT cord-280571-ntgt5hy9 68 16 affect affect VBP cord-280571-ntgt5hy9 68 17 the the DT cord-280571-ntgt5hy9 68 18 overall overall JJ cord-280571-ntgt5hy9 68 19 cost cost NN cord-280571-ntgt5hy9 68 20 per per IN cord-280571-ntgt5hy9 68 21 test test NN cord-280571-ntgt5hy9 68 22 . . . cord-280571-ntgt5hy9 69 1 In in IN cord-280571-ntgt5hy9 69 2 deciding decide VBG cord-280571-ntgt5hy9 69 3 which which WDT cord-280571-ntgt5hy9 69 4 tests test NNS cord-280571-ntgt5hy9 69 5 are be VBP cord-280571-ntgt5hy9 69 6 appropriate appropriate JJ cord-280571-ntgt5hy9 69 7 and and CC cord-280571-ntgt5hy9 69 8 at at IN cord-280571-ntgt5hy9 69 9 what what WDT cord-280571-ntgt5hy9 69 10 cost cost NN cord-280571-ntgt5hy9 69 11 for for IN cord-280571-ntgt5hy9 69 12 the the DT cord-280571-ntgt5hy9 69 13 patient patient JJ cord-280571-ntgt5hy9 69 14 population population NN cord-280571-ntgt5hy9 69 15 at at IN cord-280571-ntgt5hy9 69 16 a a DT cord-280571-ntgt5hy9 69 17 particular particular JJ cord-280571-ntgt5hy9 69 18 health health NN cord-280571-ntgt5hy9 69 19 care care NN cord-280571-ntgt5hy9 69 20 facility facility NN cord-280571-ntgt5hy9 69 21 , , , cord-280571-ntgt5hy9 69 22 all all DT cord-280571-ntgt5hy9 69 23 of of IN cord-280571-ntgt5hy9 69 24 the the DT cord-280571-ntgt5hy9 69 25 above above JJ cord-280571-ntgt5hy9 69 26 factors factor NNS cord-280571-ntgt5hy9 69 27 need need VBP cord-280571-ntgt5hy9 69 28 to to TO cord-280571-ntgt5hy9 69 29 be be VB cord-280571-ntgt5hy9 69 30 considered consider VBN cord-280571-ntgt5hy9 69 31 in in IN cord-280571-ntgt5hy9 69 32 light light NN cord-280571-ntgt5hy9 69 33 of of IN cord-280571-ntgt5hy9 69 34 the the DT cord-280571-ntgt5hy9 69 35 clinical clinical JJ cord-280571-ntgt5hy9 69 36 impact impact NN cord-280571-ntgt5hy9 69 37 of of IN cord-280571-ntgt5hy9 69 38 the the DT cord-280571-ntgt5hy9 69 39 test test NN cord-280571-ntgt5hy9 69 40 result result NN cord-280571-ntgt5hy9 69 41 . . . cord-280571-ntgt5hy9 70 1 The the DT cord-280571-ntgt5hy9 70 2 use use NN cord-280571-ntgt5hy9 70 3 of of IN cord-280571-ntgt5hy9 70 4 NAATs NAATs NNP cord-280571-ntgt5hy9 70 5 is be VBZ cord-280571-ntgt5hy9 70 6 an an DT cord-280571-ntgt5hy9 70 7 intrinsic intrinsic JJ cord-280571-ntgt5hy9 70 8 part part NN cord-280571-ntgt5hy9 70 9 of of IN cord-280571-ntgt5hy9 70 10 infectious infectious JJ cord-280571-ntgt5hy9 70 11 disease disease NN cord-280571-ntgt5hy9 70 12 diagnostics diagnostic NNS cord-280571-ntgt5hy9 70 13 . . . cord-280571-ntgt5hy9 71 1 The the DT cord-280571-ntgt5hy9 71 2 ability ability NN cord-280571-ntgt5hy9 71 3 of of IN cord-280571-ntgt5hy9 71 4 NAATs NAATs NNPS cord-280571-ntgt5hy9 71 5 to to TO cord-280571-ntgt5hy9 71 6 rapidly rapidly RB cord-280571-ntgt5hy9 71 7 and and CC cord-280571-ntgt5hy9 71 8 accurately accurately RB cord-280571-ntgt5hy9 71 9 detect detect VB cord-280571-ntgt5hy9 71 10 a a DT cord-280571-ntgt5hy9 71 11 novel novel JJ cord-280571-ntgt5hy9 71 12 pathogen pathogen NN cord-280571-ntgt5hy9 71 13 was be VBD cord-280571-ntgt5hy9 71 14 best well RBS cord-280571-ntgt5hy9 71 15 exemplified exemplify VBN cord-280571-ntgt5hy9 71 16 during during IN cord-280571-ntgt5hy9 71 17 the the DT cord-280571-ntgt5hy9 71 18 2009 2009 CD cord-280571-ntgt5hy9 71 19 influenza influenza NN cord-280571-ntgt5hy9 71 20 A a DT cord-280571-ntgt5hy9 71 21 H1N1 H1N1 NNP cord-280571-ntgt5hy9 71 22 pandemic pandemic NN cord-280571-ntgt5hy9 71 23 [ [ -LRB- cord-280571-ntgt5hy9 71 24 5 5 CD cord-280571-ntgt5hy9 71 25 , , , cord-280571-ntgt5hy9 71 26 [ [ -LRB- cord-280571-ntgt5hy9 71 27 22 22 CD cord-280571-ntgt5hy9 71 28 ] ] -RRB- cord-280571-ntgt5hy9 71 29 [ [ -LRB- cord-280571-ntgt5hy9 71 30 23 23 CD cord-280571-ntgt5hy9 71 31 ] ] -RRB- cord-280571-ntgt5hy9 71 32 [ [ -LRB- cord-280571-ntgt5hy9 71 33 24 24 CD cord-280571-ntgt5hy9 71 34 ] ] -RRB- cord-280571-ntgt5hy9 71 35 . . . cord-280571-ntgt5hy9 72 1 NAATs naat NNS cord-280571-ntgt5hy9 72 2 are be VBP cord-280571-ntgt5hy9 72 3 especially especially RB cord-280571-ntgt5hy9 72 4 suited suit VBN cord-280571-ntgt5hy9 72 5 for for IN cord-280571-ntgt5hy9 72 6 the the DT cord-280571-ntgt5hy9 72 7 identification identification NN cord-280571-ntgt5hy9 72 8 of of IN cord-280571-ntgt5hy9 72 9 respiratory respiratory JJ cord-280571-ntgt5hy9 72 10 pathogens pathogen NNS cord-280571-ntgt5hy9 72 11 that that WDT cord-280571-ntgt5hy9 72 12 are be VBP cord-280571-ntgt5hy9 72 13 not not RB cord-280571-ntgt5hy9 72 14 routinely routinely RB cord-280571-ntgt5hy9 72 15 or or CC cord-280571-ntgt5hy9 72 16 easily easily RB cord-280571-ntgt5hy9 72 17 cultured cultured JJ cord-280571-ntgt5hy9 72 18 ( ( -LRB- cord-280571-ntgt5hy9 72 19 eg eg NN cord-280571-ntgt5hy9 72 20 , , , cord-280571-ntgt5hy9 72 21 hMPV hMPV NNP cord-280571-ntgt5hy9 72 22 , , , cord-280571-ntgt5hy9 72 23 bocavirus bocavirus NNP cord-280571-ntgt5hy9 72 24 , , , cord-280571-ntgt5hy9 72 25 parainfluenza parainfluenza NNP cord-280571-ntgt5hy9 72 26 4 4 CD cord-280571-ntgt5hy9 72 27 , , , cord-280571-ntgt5hy9 72 28 and and CC cord-280571-ntgt5hy9 72 29 Chlamydophila Chlamydophila NNP cord-280571-ntgt5hy9 72 30 pneumoniae pneumoniae NN cord-280571-ntgt5hy9 72 31 ) ) -RRB- cord-280571-ntgt5hy9 72 32 , , , cord-280571-ntgt5hy9 72 33 pathogens pathogen NNS cord-280571-ntgt5hy9 72 34 that that WDT cord-280571-ntgt5hy9 72 35 are be VBP cord-280571-ntgt5hy9 72 36 dangerous dangerous JJ cord-280571-ntgt5hy9 72 37 to to IN cord-280571-ntgt5hy9 72 38 culture culture NN cord-280571-ntgt5hy9 72 39 ( ( -LRB- cord-280571-ntgt5hy9 72 40 eg eg IN cord-280571-ntgt5hy9 72 41 , , , cord-280571-ntgt5hy9 72 42 severe severe JJ cord-280571-ntgt5hy9 72 43 acute acute JJ cord-280571-ntgt5hy9 72 44 respiratory respiratory JJ cord-280571-ntgt5hy9 72 45 syndrome syndrome NN cord-280571-ntgt5hy9 72 46 coronavirus coronavirus NN cord-280571-ntgt5hy9 72 47 ) ) -RRB- cord-280571-ntgt5hy9 72 48 , , , cord-280571-ntgt5hy9 72 49 pathogens pathogen NNS cord-280571-ntgt5hy9 72 50 for for IN cord-280571-ntgt5hy9 72 51 which which WDT cord-280571-ntgt5hy9 72 52 the the DT cord-280571-ntgt5hy9 72 53 time time NN cord-280571-ntgt5hy9 72 54 to to IN cord-280571-ntgt5hy9 72 55 detection detection NN cord-280571-ntgt5hy9 72 56 by by IN cord-280571-ntgt5hy9 72 57 traditional traditional JJ cord-280571-ntgt5hy9 72 58 means mean NNS cord-280571-ntgt5hy9 72 59 is be VBZ cord-280571-ntgt5hy9 72 60 often often RB cord-280571-ntgt5hy9 72 61 too too RB cord-280571-ntgt5hy9 72 62 delayed delay VBN cord-280571-ntgt5hy9 72 63 to to TO cord-280571-ntgt5hy9 72 64 affect affect VB cord-280571-ntgt5hy9 72 65 patient patient JJ cord-280571-ntgt5hy9 72 66 care care NN cord-280571-ntgt5hy9 72 67 ( ( -LRB- cord-280571-ntgt5hy9 72 68 eg eg RB cord-280571-ntgt5hy9 72 69 , , , cord-280571-ntgt5hy9 72 70 tube tube NN cord-280571-ntgt5hy9 72 71 cell cell NN cord-280571-ntgt5hy9 72 72 culture culture NN cord-280571-ntgt5hy9 72 73 for for IN cord-280571-ntgt5hy9 72 74 influenza influenza NN cord-280571-ntgt5hy9 72 75 ) ) -RRB- cord-280571-ntgt5hy9 72 76 , , , cord-280571-ntgt5hy9 72 77 and and CC cord-280571-ntgt5hy9 72 78 pathogens pathogen NNS cord-280571-ntgt5hy9 72 79 for for IN cord-280571-ntgt5hy9 72 80 which which WDT cord-280571-ntgt5hy9 72 81 serologic serologic NNP cord-280571-ntgt5hy9 72 82 testing testing NN cord-280571-ntgt5hy9 72 83 is be VBZ cord-280571-ntgt5hy9 72 84 difficult difficult JJ cord-280571-ntgt5hy9 72 85 to to TO cord-280571-ntgt5hy9 72 86 interpret interpret VB cord-280571-ntgt5hy9 72 87 ( ( -LRB- cord-280571-ntgt5hy9 72 88 eg eg NNS cord-280571-ntgt5hy9 72 89 , , , cord-280571-ntgt5hy9 72 90 C. C. NNP cord-280571-ntgt5hy9 72 91 pneumoniae pneumoniae NN cord-280571-ntgt5hy9 72 92 ) ) -RRB- cord-280571-ntgt5hy9 72 93 . . . cord-280571-ntgt5hy9 73 1 In in IN cord-280571-ntgt5hy9 73 2 most most JJS cord-280571-ntgt5hy9 73 3 cases case NNS cord-280571-ntgt5hy9 73 4 , , , cord-280571-ntgt5hy9 73 5 NAATs NAATs NNPS cord-280571-ntgt5hy9 73 6 offer offer VBP cord-280571-ntgt5hy9 73 7 enhanced enhanced JJ cord-280571-ntgt5hy9 73 8 sensitivity sensitivity NN cord-280571-ntgt5hy9 73 9 over over IN cord-280571-ntgt5hy9 73 10 culture culture NN cord-280571-ntgt5hy9 73 11 methods method NNS cord-280571-ntgt5hy9 73 12 , , , cord-280571-ntgt5hy9 73 13 RADTS radt NNS cord-280571-ntgt5hy9 73 14 , , , cord-280571-ntgt5hy9 73 15 and and CC cord-280571-ntgt5hy9 73 16 DFA DFA NNP cord-280571-ntgt5hy9 73 17 testing test VBG cord-280571-ntgt5hy9 73 18 [ [ -LRB- cord-280571-ntgt5hy9 73 19 5 5 CD cord-280571-ntgt5hy9 73 20 , , , cord-280571-ntgt5hy9 73 21 6 6 CD cord-280571-ntgt5hy9 73 22 , , , cord-280571-ntgt5hy9 73 23 10 10 CD cord-280571-ntgt5hy9 73 24 ] ] -RRB- cord-280571-ntgt5hy9 73 25 . . . cord-280571-ntgt5hy9 74 1 The the DT cord-280571-ntgt5hy9 74 2 specificity specificity NN cord-280571-ntgt5hy9 74 3 of of IN cord-280571-ntgt5hy9 74 4 NAATs NAATs NNP cord-280571-ntgt5hy9 74 5 varies vary VBZ cord-280571-ntgt5hy9 74 6 with with IN cord-280571-ntgt5hy9 74 7 target target NN cord-280571-ntgt5hy9 74 8 and and CC cord-280571-ntgt5hy9 74 9 assay assay NN cord-280571-ntgt5hy9 74 10 design design NN cord-280571-ntgt5hy9 74 11 but but CC cord-280571-ntgt5hy9 74 12 is be VBZ cord-280571-ntgt5hy9 74 13 generally generally RB cord-280571-ntgt5hy9 74 14 very very RB cord-280571-ntgt5hy9 74 15 high high JJ cord-280571-ntgt5hy9 74 16 . . . cord-280571-ntgt5hy9 75 1 In in IN cord-280571-ntgt5hy9 75 2 addition addition NN cord-280571-ntgt5hy9 75 3 , , , cord-280571-ntgt5hy9 75 4 laboratorydeveloped laboratorydeveloped NNP cord-280571-ntgt5hy9 75 5 NAATs NAATs NNP cord-280571-ntgt5hy9 75 6 validated validate VBN cord-280571-ntgt5hy9 75 7 in in IN cord-280571-ntgt5hy9 75 8 accordance accordance NN cord-280571-ntgt5hy9 75 9 with with IN cord-280571-ntgt5hy9 75 10 the the DT cord-280571-ntgt5hy9 75 11 Clinical Clinical NNP cord-280571-ntgt5hy9 75 12 Laboratory Laboratory NNP cord-280571-ntgt5hy9 75 13 Improvement Improvement NNP cord-280571-ntgt5hy9 75 14 Amendments Amendments NNP cord-280571-ntgt5hy9 75 15 ( ( -LRB- cord-280571-ntgt5hy9 75 16 CLIA CLIA NNP cord-280571-ntgt5hy9 75 17 ) ) -RRB- cord-280571-ntgt5hy9 75 18 requirements requirement NNS cord-280571-ntgt5hy9 75 19 can can MD cord-280571-ntgt5hy9 75 20 be be VB cord-280571-ntgt5hy9 75 21 used use VBN cord-280571-ntgt5hy9 75 22 to to TO cord-280571-ntgt5hy9 75 23 identify identify VB cord-280571-ntgt5hy9 75 24 new new JJ cord-280571-ntgt5hy9 75 25 pathogens pathogen NNS cord-280571-ntgt5hy9 75 26 until until IN cord-280571-ntgt5hy9 75 27 FDA FDA NNP cord-280571-ntgt5hy9 75 28 - - HYPH cord-280571-ntgt5hy9 75 29 approved/ approved/ NNP cord-280571-ntgt5hy9 75 30 cleared clear VBN cord-280571-ntgt5hy9 75 31 in in IN cord-280571-ntgt5hy9 75 32 vitro vitro FW cord-280571-ntgt5hy9 75 33 diagnostic diagnostic JJ cord-280571-ntgt5hy9 75 34 ( ( -LRB- cord-280571-ntgt5hy9 75 35 IVD IVD NNP cord-280571-ntgt5hy9 75 36 ) ) -RRB- cord-280571-ntgt5hy9 75 37 devices device NNS cord-280571-ntgt5hy9 75 38 become become VBP cord-280571-ntgt5hy9 75 39 available available JJ cord-280571-ntgt5hy9 75 40 . . . cord-280571-ntgt5hy9 76 1 With with IN cord-280571-ntgt5hy9 76 2 clinical clinical JJ cord-280571-ntgt5hy9 76 3 integration integration NN cord-280571-ntgt5hy9 76 4 of of IN cord-280571-ntgt5hy9 76 5 real real JJ cord-280571-ntgt5hy9 76 6 - - HYPH cord-280571-ntgt5hy9 76 7 time time NN cord-280571-ntgt5hy9 76 8 polymerase polymerase NN cord-280571-ntgt5hy9 76 9 chain chain NN cord-280571-ntgt5hy9 76 10 reaction reaction NN cord-280571-ntgt5hy9 76 11 ( ( -LRB- cord-280571-ntgt5hy9 76 12 PCR PCR NNP cord-280571-ntgt5hy9 76 13 ) ) -RRB- cord-280571-ntgt5hy9 76 14 and and CC cord-280571-ntgt5hy9 76 15 FDA FDA NNP cord-280571-ntgt5hy9 76 16 - - HYPH cord-280571-ntgt5hy9 76 17 approved approve VBN cord-280571-ntgt5hy9 76 18 / / SYM cord-280571-ntgt5hy9 76 19 cleared clear VBD cord-280571-ntgt5hy9 76 20 simple simple JJ cord-280571-ntgt5hy9 76 21 cartridge cartridge NN cord-280571-ntgt5hy9 76 22 - - HYPH cord-280571-ntgt5hy9 76 23 based base VBN cord-280571-ntgt5hy9 76 24 NAATs naat NNS cord-280571-ntgt5hy9 76 25 , , , cord-280571-ntgt5hy9 76 26 laboratories laboratory NNS cord-280571-ntgt5hy9 76 27 of of IN cord-280571-ntgt5hy9 76 28 all all DT cord-280571-ntgt5hy9 76 29 sizes size NNS cord-280571-ntgt5hy9 76 30 are be VBP cord-280571-ntgt5hy9 76 31 now now RB cord-280571-ntgt5hy9 76 32 able able JJ cord-280571-ntgt5hy9 76 33 to to TO cord-280571-ntgt5hy9 76 34 perform perform VB cord-280571-ntgt5hy9 76 35 molecular molecular JJ cord-280571-ntgt5hy9 76 36 diagnostic diagnostic JJ cord-280571-ntgt5hy9 76 37 tests test NNS cord-280571-ntgt5hy9 76 38 . . . cord-280571-ntgt5hy9 77 1 The the DT cord-280571-ntgt5hy9 77 2 detection detection NN cord-280571-ntgt5hy9 77 3 of of IN cord-280571-ntgt5hy9 77 4 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 77 5 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 77 6 directly directly RB cord-280571-ntgt5hy9 77 7 in in IN cord-280571-ntgt5hy9 77 8 a a DT cord-280571-ntgt5hy9 77 9 clinical clinical JJ cord-280571-ntgt5hy9 77 10 sample sample NN cord-280571-ntgt5hy9 77 11 from from IN cord-280571-ntgt5hy9 77 12 a a DT cord-280571-ntgt5hy9 77 13 patient patient NN cord-280571-ntgt5hy9 77 14 not not RB cord-280571-ntgt5hy9 77 15 yet yet RB cord-280571-ntgt5hy9 77 16 identified identify VBN cord-280571-ntgt5hy9 77 17 as as IN cord-280571-ntgt5hy9 77 18 M. M. NNP cord-280571-ntgt5hy9 77 19 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 77 20 positive positive JJ cord-280571-ntgt5hy9 77 21 is be VBZ cord-280571-ntgt5hy9 77 22 always always RB cord-280571-ntgt5hy9 77 23 clinically clinically RB cord-280571-ntgt5hy9 77 24 relevant relevant JJ cord-280571-ntgt5hy9 77 25 . . . cord-280571-ntgt5hy9 78 1 Detection detection NN cord-280571-ntgt5hy9 78 2 of of IN cord-280571-ntgt5hy9 78 3 such such JJ cord-280571-ntgt5hy9 78 4 bacterial bacterial JJ cord-280571-ntgt5hy9 78 5 pathogens pathogen NNS cord-280571-ntgt5hy9 78 6 as as IN cord-280571-ntgt5hy9 78 7 Bordetella Bordetella NNP cord-280571-ntgt5hy9 78 8 pertussis pertussis NN cord-280571-ntgt5hy9 78 9 , , , cord-280571-ntgt5hy9 78 10 Bordetella Bordetella NNP cord-280571-ntgt5hy9 78 11 parapertussis parapertussis NN cord-280571-ntgt5hy9 78 12 , , , cord-280571-ntgt5hy9 78 13 Legionella Legionella NNP cord-280571-ntgt5hy9 78 14 pneumophila pneumophila NN cord-280571-ntgt5hy9 78 15 , , , cord-280571-ntgt5hy9 78 16 Mycoplasma mycoplasma NN cord-280571-ntgt5hy9 78 17 pneumoniae pneumoniae NN cord-280571-ntgt5hy9 78 18 , , , cord-280571-ntgt5hy9 78 19 or or CC cord-280571-ntgt5hy9 78 20 C. C. NNP cord-280571-ntgt5hy9 78 21 pneumoniae pneumoniae NNS cord-280571-ntgt5hy9 78 22 usually usually RB cord-280571-ntgt5hy9 78 23 indicates indicate VBZ cord-280571-ntgt5hy9 78 24 active active JJ cord-280571-ntgt5hy9 78 25 infection infection NN cord-280571-ntgt5hy9 78 26 . . . cord-280571-ntgt5hy9 79 1 In in IN cord-280571-ntgt5hy9 79 2 contrast contrast NN cord-280571-ntgt5hy9 79 3 , , , cord-280571-ntgt5hy9 79 4 the the DT cord-280571-ntgt5hy9 79 5 detection detection NN cord-280571-ntgt5hy9 79 6 of of IN cord-280571-ntgt5hy9 79 7 other other JJ cord-280571-ntgt5hy9 79 8 bacteria bacteria NNS cord-280571-ntgt5hy9 79 9 , , , cord-280571-ntgt5hy9 79 10 such such JJ cord-280571-ntgt5hy9 79 11 as as IN cord-280571-ntgt5hy9 79 12 Streptococcus streptococcus NN cord-280571-ntgt5hy9 79 13 pneumoniae pneumoniae NN cord-280571-ntgt5hy9 79 14 , , , cord-280571-ntgt5hy9 79 15 may may MD cord-280571-ntgt5hy9 79 16 indicate indicate VB cord-280571-ntgt5hy9 79 17 infection infection NN cord-280571-ntgt5hy9 79 18 or or CC cord-280571-ntgt5hy9 79 19 simply simply RB cord-280571-ntgt5hy9 79 20 colonization colonization NN cord-280571-ntgt5hy9 79 21 . . . cord-280571-ntgt5hy9 80 1 Therefore therefore RB cord-280571-ntgt5hy9 80 2 , , , cord-280571-ntgt5hy9 80 3 interpretation interpretation NN cord-280571-ntgt5hy9 80 4 of of IN cord-280571-ntgt5hy9 80 5 the the DT cord-280571-ntgt5hy9 80 6 molecular molecular JJ cord-280571-ntgt5hy9 80 7 detection detection NN cord-280571-ntgt5hy9 80 8 of of IN cord-280571-ntgt5hy9 80 9 many many JJ cord-280571-ntgt5hy9 80 10 bacterial bacterial JJ cord-280571-ntgt5hy9 80 11 pathogens pathogen NNS cord-280571-ntgt5hy9 80 12 must must MD cord-280571-ntgt5hy9 80 13 be be VB cord-280571-ntgt5hy9 80 14 viewed view VBN cord-280571-ntgt5hy9 80 15 in in IN cord-280571-ntgt5hy9 80 16 light light NN cord-280571-ntgt5hy9 80 17 of of IN cord-280571-ntgt5hy9 80 18 the the DT cord-280571-ntgt5hy9 80 19 clinical clinical JJ cord-280571-ntgt5hy9 80 20 specimen specimen NN cord-280571-ntgt5hy9 80 21 ( ( -LRB- cord-280571-ntgt5hy9 80 22 sterile sterile JJ cord-280571-ntgt5hy9 80 23 vs vs IN cord-280571-ntgt5hy9 80 24 nonsterile nonsterile NNP cord-280571-ntgt5hy9 80 25 body body NN cord-280571-ntgt5hy9 80 26 site site NN cord-280571-ntgt5hy9 80 27 ) ) -RRB- cord-280571-ntgt5hy9 80 28 and and CC cord-280571-ntgt5hy9 80 29 determination determination NN cord-280571-ntgt5hy9 80 30 of of IN cord-280571-ntgt5hy9 80 31 the the DT cord-280571-ntgt5hy9 80 32 quantity quantity NN cord-280571-ntgt5hy9 80 33 of of IN cord-280571-ntgt5hy9 80 34 organisms organism NNS cord-280571-ntgt5hy9 80 35 present present JJ cord-280571-ntgt5hy9 80 36 . . . cord-280571-ntgt5hy9 81 1 In in IN cord-280571-ntgt5hy9 81 2 addition addition NN cord-280571-ntgt5hy9 81 3 , , , cord-280571-ntgt5hy9 81 4 molecular molecular JJ cord-280571-ntgt5hy9 81 5 methods method NNS cord-280571-ntgt5hy9 81 6 must must MD cord-280571-ntgt5hy9 81 7 include include VB cord-280571-ntgt5hy9 81 8 all all DT cord-280571-ntgt5hy9 81 9 potential potential JJ cord-280571-ntgt5hy9 81 10 pathogens pathogen NNS cord-280571-ntgt5hy9 81 11 , , , cord-280571-ntgt5hy9 81 12 even even RB cord-280571-ntgt5hy9 81 13 though though IN cord-280571-ntgt5hy9 81 14 culture culture NN cord-280571-ntgt5hy9 81 15 is be VBZ cord-280571-ntgt5hy9 81 16 still still RB cord-280571-ntgt5hy9 81 17 required require VBN cord-280571-ntgt5hy9 81 18 for for IN cord-280571-ntgt5hy9 81 19 antimicrobial antimicrobial JJ cord-280571-ntgt5hy9 81 20 susceptibility susceptibility NN cord-280571-ntgt5hy9 81 21 testing testing NN cord-280571-ntgt5hy9 81 22 . . . cord-280571-ntgt5hy9 82 1 For for IN cord-280571-ntgt5hy9 82 2 these these DT cord-280571-ntgt5hy9 82 3 reasons reason NNS cord-280571-ntgt5hy9 82 4 , , , cord-280571-ntgt5hy9 82 5 there there EX cord-280571-ntgt5hy9 82 6 is be VBZ cord-280571-ntgt5hy9 82 7 currently currently RB cord-280571-ntgt5hy9 82 8 a a DT cord-280571-ntgt5hy9 82 9 scarcity scarcity NN cord-280571-ntgt5hy9 82 10 of of IN cord-280571-ntgt5hy9 82 11 FDA FDA NNP cord-280571-ntgt5hy9 82 12 - - HYPH cord-280571-ntgt5hy9 82 13 approved approve VBN cord-280571-ntgt5hy9 82 14 / / SYM cord-280571-ntgt5hy9 82 15 cleared clear VBN cord-280571-ntgt5hy9 82 16 assays assay NNS cord-280571-ntgt5hy9 82 17 for for IN cord-280571-ntgt5hy9 82 18 nonviral nonviral JJ cord-280571-ntgt5hy9 82 19 respiratory respiratory JJ cord-280571-ntgt5hy9 82 20 pathogens pathogen NNS cord-280571-ntgt5hy9 82 21 ( ( -LRB- cord-280571-ntgt5hy9 82 22 Table table NN cord-280571-ntgt5hy9 82 23 1 1 CD cord-280571-ntgt5hy9 82 24 ) ) -RRB- cord-280571-ntgt5hy9 82 25 . . . cord-280571-ntgt5hy9 83 1 For for IN cord-280571-ntgt5hy9 83 2 such such JJ cord-280571-ntgt5hy9 83 3 targets target NNS cord-280571-ntgt5hy9 83 4 as as IN cord-280571-ntgt5hy9 83 5 the the DT cord-280571-ntgt5hy9 83 6 atypical atypical JJ cord-280571-ntgt5hy9 83 7 pneumonia pneumonia NN cord-280571-ntgt5hy9 83 8 pathogens pathogen NNS cord-280571-ntgt5hy9 83 9 , , , cord-280571-ntgt5hy9 83 10 the the DT cord-280571-ntgt5hy9 83 11 interpretation interpretation NN cord-280571-ntgt5hy9 83 12 of of IN cord-280571-ntgt5hy9 83 13 NAAT NAAT NNP cord-280571-ntgt5hy9 83 14 results result NNS cord-280571-ntgt5hy9 83 15 is be VBZ cord-280571-ntgt5hy9 83 16 generally generally RB cord-280571-ntgt5hy9 83 17 not not RB cord-280571-ntgt5hy9 83 18 an an DT cord-280571-ntgt5hy9 83 19 issue issue NN cord-280571-ntgt5hy9 83 20 , , , cord-280571-ntgt5hy9 83 21 quantitative quantitative JJ cord-280571-ntgt5hy9 83 22 tests test NNS cord-280571-ntgt5hy9 83 23 are be VBP cord-280571-ntgt5hy9 83 24 not not RB cord-280571-ntgt5hy9 83 25 necessarily necessarily RB cord-280571-ntgt5hy9 83 26 indicated indicate VBN cord-280571-ntgt5hy9 83 27 , , , cord-280571-ntgt5hy9 83 28 and and CC cord-280571-ntgt5hy9 83 29 NAATS NAATS NNP cord-280571-ntgt5hy9 83 30 could could MD cord-280571-ntgt5hy9 83 31 replace replace VB cord-280571-ntgt5hy9 83 32 traditional traditional JJ cord-280571-ntgt5hy9 83 33 test test NN cord-280571-ntgt5hy9 83 34 methods method NNS cord-280571-ntgt5hy9 83 35 . . . cord-280571-ntgt5hy9 84 1 However however RB cord-280571-ntgt5hy9 84 2 , , , cord-280571-ntgt5hy9 84 3 the the DT cord-280571-ntgt5hy9 84 4 lack lack NN cord-280571-ntgt5hy9 84 5 of of IN cord-280571-ntgt5hy9 84 6 FDA FDA NNP cord-280571-ntgt5hy9 84 7 - - HYPH cord-280571-ntgt5hy9 84 8 approved approve VBN cord-280571-ntgt5hy9 84 9 / / SYM cord-280571-ntgt5hy9 84 10 cleared clear VBN cord-280571-ntgt5hy9 84 11 NAATs NAATs NNP cord-280571-ntgt5hy9 84 12 for for IN cord-280571-ntgt5hy9 84 13 these these DT cord-280571-ntgt5hy9 84 14 pathogens pathogen NNS cord-280571-ntgt5hy9 84 15 most most RBS cord-280571-ntgt5hy9 84 16 probably probably RB cord-280571-ntgt5hy9 84 17 relates relate VBZ cord-280571-ntgt5hy9 84 18 to to IN cord-280571-ntgt5hy9 84 19 the the DT cord-280571-ntgt5hy9 84 20 IVD IVD NNP cord-280571-ntgt5hy9 84 21 device device NN cord-280571-ntgt5hy9 84 22 manufacturers manufacturer NNS cord-280571-ntgt5hy9 84 23 ' ' POS cord-280571-ntgt5hy9 84 24 reluctance reluctance NN cord-280571-ntgt5hy9 84 25 to to TO cord-280571-ntgt5hy9 84 26 perform perform VB cord-280571-ntgt5hy9 84 27 costly costly JJ cord-280571-ntgt5hy9 84 28 clinical clinical JJ cord-280571-ntgt5hy9 84 29 trials trial NNS cord-280571-ntgt5hy9 84 30 for for IN cord-280571-ntgt5hy9 84 31 targets target NNS cord-280571-ntgt5hy9 84 32 with with IN cord-280571-ntgt5hy9 84 33 a a DT cord-280571-ntgt5hy9 84 34 relatively relatively RB cord-280571-ntgt5hy9 84 35 low low JJ cord-280571-ntgt5hy9 84 36 prevalence prevalence NN cord-280571-ntgt5hy9 84 37 rate rate NN cord-280571-ntgt5hy9 84 38 and and CC cord-280571-ntgt5hy9 84 39 for for IN cord-280571-ntgt5hy9 84 40 which which WDT cord-280571-ntgt5hy9 84 41 the the DT cord-280571-ntgt5hy9 84 42 potential potential JJ cord-280571-ntgt5hy9 84 43 volume volume NN cord-280571-ntgt5hy9 84 44 of of IN cord-280571-ntgt5hy9 84 45 testing testing NN cord-280571-ntgt5hy9 84 46 may may MD cord-280571-ntgt5hy9 84 47 be be VB cord-280571-ntgt5hy9 84 48 minimal minimal JJ cord-280571-ntgt5hy9 84 49 . . . cord-280571-ntgt5hy9 85 1 In in IN cord-280571-ntgt5hy9 85 2 light light NN cord-280571-ntgt5hy9 85 3 of of IN cord-280571-ntgt5hy9 85 4 the the DT cord-280571-ntgt5hy9 85 5 rise rise NN cord-280571-ntgt5hy9 85 6 in in IN cord-280571-ntgt5hy9 85 7 M. M. NNP cord-280571-ntgt5hy9 85 8 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 85 9 drug drug NN cord-280571-ntgt5hy9 85 10 resistance resistance NN cord-280571-ntgt5hy9 85 11 worldwide worldwide RB cord-280571-ntgt5hy9 85 12 , , , cord-280571-ntgt5hy9 85 13 the the DT cord-280571-ntgt5hy9 85 14 rapid rapid JJ cord-280571-ntgt5hy9 85 15 identification identification NN cord-280571-ntgt5hy9 85 16 of of IN cord-280571-ntgt5hy9 85 17 patients patient NNS cord-280571-ntgt5hy9 85 18 with with IN cord-280571-ntgt5hy9 85 19 pulmonary pulmonary JJ cord-280571-ntgt5hy9 85 20 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 85 21 is be VBZ cord-280571-ntgt5hy9 85 22 essential essential JJ cord-280571-ntgt5hy9 85 23 and and CC cord-280571-ntgt5hy9 85 24 allows allow VBZ cord-280571-ntgt5hy9 85 25 for for IN cord-280571-ntgt5hy9 85 26 improved improved JJ cord-280571-ntgt5hy9 85 27 patient patient JJ cord-280571-ntgt5hy9 85 28 outcomes outcome NNS cord-280571-ntgt5hy9 85 29 , , , cord-280571-ntgt5hy9 85 30 the the DT cord-280571-ntgt5hy9 85 31 appropriate appropriate JJ cord-280571-ntgt5hy9 85 32 use use NN cord-280571-ntgt5hy9 85 33 of of IN cord-280571-ntgt5hy9 85 34 isolation isolation NN cord-280571-ntgt5hy9 85 35 facilities facility NNS cord-280571-ntgt5hy9 85 36 , , , cord-280571-ntgt5hy9 85 37 the the DT cord-280571-ntgt5hy9 85 38 initiation initiation NN cord-280571-ntgt5hy9 85 39 of of IN cord-280571-ntgt5hy9 85 40 appropriate appropriate JJ cord-280571-ntgt5hy9 85 41 treatment treatment NN cord-280571-ntgt5hy9 85 42 , , , cord-280571-ntgt5hy9 85 43 and and CC cord-280571-ntgt5hy9 85 44 the the DT cord-280571-ntgt5hy9 85 45 identification identification NN cord-280571-ntgt5hy9 85 46 of of IN cord-280571-ntgt5hy9 85 47 possible possible JJ cord-280571-ntgt5hy9 85 48 infected infect VBN cord-280571-ntgt5hy9 85 49 contacts contact NNS cord-280571-ntgt5hy9 85 50 [ [ -LRB- cord-280571-ntgt5hy9 85 51 25 25 CD cord-280571-ntgt5hy9 85 52 ] ] -RRB- cord-280571-ntgt5hy9 85 53 [ [ -LRB- cord-280571-ntgt5hy9 85 54 26 26 CD cord-280571-ntgt5hy9 85 55 ] ] -RRB- cord-280571-ntgt5hy9 85 56 [ [ -LRB- cord-280571-ntgt5hy9 85 57 27 27 CD cord-280571-ntgt5hy9 85 58 ] ] -RRB- cord-280571-ntgt5hy9 85 59 . . . cord-280571-ntgt5hy9 86 1 In in IN cord-280571-ntgt5hy9 86 2 addition addition NN cord-280571-ntgt5hy9 86 3 , , , cord-280571-ntgt5hy9 86 4 studies study NNS cord-280571-ntgt5hy9 86 5 have have VBP cord-280571-ntgt5hy9 86 6 shown show VBN cord-280571-ntgt5hy9 86 7 that that IN cord-280571-ntgt5hy9 86 8 the the DT cord-280571-ntgt5hy9 86 9 estimated estimate VBN cord-280571-ntgt5hy9 86 10 costs cost NNS cord-280571-ntgt5hy9 86 11 associated associate VBN cord-280571-ntgt5hy9 86 12 with with IN cord-280571-ntgt5hy9 86 13 an an DT cord-280571-ntgt5hy9 86 14 inaccurate inaccurate JJ cord-280571-ntgt5hy9 86 15 diagnosis diagnosis NN cord-280571-ntgt5hy9 86 16 of of IN cord-280571-ntgt5hy9 86 17 M. M. NNP cord-280571-ntgt5hy9 86 18 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 86 19 infection infection NN cord-280571-ntgt5hy9 86 20 are be VBP cord-280571-ntgt5hy9 86 21 substantial substantial JJ cord-280571-ntgt5hy9 86 22 ( ( -LRB- cord-280571-ntgt5hy9 86 23 $ $ $ cord-280571-ntgt5hy9 86 24 11,576 11,576 CD cord-280571-ntgt5hy9 86 25 per per IN cord-280571-ntgt5hy9 86 26 patient patient NN cord-280571-ntgt5hy9 86 27 ) ) -RRB- cord-280571-ntgt5hy9 86 28 because because IN cord-280571-ntgt5hy9 86 29 of of IN cord-280571-ntgt5hy9 86 30 institutional institutional JJ cord-280571-ntgt5hy9 86 31 isolation isolation NN cord-280571-ntgt5hy9 86 32 procedures procedure NNS cord-280571-ntgt5hy9 86 33 [ [ -LRB- cord-280571-ntgt5hy9 86 34 27 27 CD cord-280571-ntgt5hy9 86 35 ] ] -RRB- cord-280571-ntgt5hy9 86 36 . . . cord-280571-ntgt5hy9 87 1 Direct direct JJ cord-280571-ntgt5hy9 87 2 sample sample NN cord-280571-ntgt5hy9 87 3 testing testing NN cord-280571-ntgt5hy9 87 4 can can MD cord-280571-ntgt5hy9 87 5 detect detect VB cord-280571-ntgt5hy9 87 6 M. M. NNP cord-280571-ntgt5hy9 87 7 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 87 8 within within IN cord-280571-ntgt5hy9 87 9 24 24 CD cord-280571-ntgt5hy9 87 10 - - SYM cord-280571-ntgt5hy9 87 11 48 48 CD cord-280571-ntgt5hy9 87 12 h h NN cord-280571-ntgt5hy9 87 13 of of IN cord-280571-ntgt5hy9 87 14 sample sample NN cord-280571-ntgt5hy9 87 15 collection collection NN cord-280571-ntgt5hy9 87 16 , , , cord-280571-ntgt5hy9 87 17 compared compare VBN cord-280571-ntgt5hy9 87 18 with with IN cord-280571-ntgt5hy9 87 19 1 1 CD cord-280571-ntgt5hy9 87 20 - - SYM cord-280571-ntgt5hy9 87 21 4 4 CD cord-280571-ntgt5hy9 87 22 weeks week NNS cord-280571-ntgt5hy9 87 23 for for IN cord-280571-ntgt5hy9 87 24 liquid liquid JJ cord-280571-ntgt5hy9 87 25 and and CC cord-280571-ntgt5hy9 87 26 traditional traditional JJ cord-280571-ntgt5hy9 87 27 solid solid JJ cord-280571-ntgt5hy9 87 28 media medium NNS cord-280571-ntgt5hy9 87 29 culture culture NN cord-280571-ntgt5hy9 87 30 methods method NNS cord-280571-ntgt5hy9 87 31 . . . cord-280571-ntgt5hy9 88 1 Although although IN cord-280571-ntgt5hy9 88 2 acid acid NN cord-280571-ntgt5hy9 88 3 - - HYPH cord-280571-ntgt5hy9 88 4 fast fast JJ cord-280571-ntgt5hy9 88 5 bacilli bacilli JJ cord-280571-ntgt5hy9 88 6 ( ( -LRB- cord-280571-ntgt5hy9 88 7 AFB AFB NNP cord-280571-ntgt5hy9 88 8 ) ) -RRB- cord-280571-ntgt5hy9 88 9 smear smear NN cord-280571-ntgt5hy9 88 10 microscopy microscopy NN cord-280571-ntgt5hy9 88 11 is be VBZ cord-280571-ntgt5hy9 88 12 inexpensive inexpensive JJ cord-280571-ntgt5hy9 88 13 and and CC cord-280571-ntgt5hy9 88 14 rapid rapid JJ cord-280571-ntgt5hy9 88 15 to to TO cord-280571-ntgt5hy9 88 16 perform perform VB cord-280571-ntgt5hy9 88 17 , , , cord-280571-ntgt5hy9 88 18 the the DT cord-280571-ntgt5hy9 88 19 sensitivity sensitivity NN cord-280571-ntgt5hy9 88 20 of of IN cord-280571-ntgt5hy9 88 21 the the DT cord-280571-ntgt5hy9 88 22 test test NN cord-280571-ntgt5hy9 88 23 can can MD cord-280571-ntgt5hy9 88 24 be be VB cord-280571-ntgt5hy9 88 25 poor poor JJ cord-280571-ntgt5hy9 88 26 ( ( -LRB- cord-280571-ntgt5hy9 88 27 45%-80 45%-80 CD cord-280571-ntgt5hy9 88 28 % % NN cord-280571-ntgt5hy9 88 29 with with IN cord-280571-ntgt5hy9 88 30 culture culture NN cord-280571-ntgt5hy9 88 31 - - HYPH cord-280571-ntgt5hy9 88 32 confirmed confirm VBN cord-280571-ntgt5hy9 88 33 pulmonary pulmonary JJ cord-280571-ntgt5hy9 88 34 M. M. NNP cord-280571-ntgt5hy9 88 35 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 88 36 colonization colonization NN cord-280571-ntgt5hy9 88 37 or or CC cord-280571-ntgt5hy9 88 38 infection infection NN cord-280571-ntgt5hy9 88 39 ) ) -RRB- cord-280571-ntgt5hy9 88 40 and and CC cord-280571-ntgt5hy9 88 41 can can MD cord-280571-ntgt5hy9 88 42 not not RB cord-280571-ntgt5hy9 88 43 differentiate differentiate VB cord-280571-ntgt5hy9 88 44 M. M. NNP cord-280571-ntgt5hy9 88 45 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 88 46 from from IN cord-280571-ntgt5hy9 88 47 mycobacteria mycobacterium NNS cord-280571-ntgt5hy9 88 48 other other JJ cord-280571-ntgt5hy9 88 49 than than IN cord-280571-ntgt5hy9 88 50 M. M. NNP cord-280571-ntgt5hy9 88 51 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 88 52 [ [ -LRB- cord-280571-ntgt5hy9 88 53 26 26 CD cord-280571-ntgt5hy9 88 54 ] ] -RRB- cord-280571-ntgt5hy9 88 55 . . . cord-280571-ntgt5hy9 89 1 The the DT cord-280571-ntgt5hy9 89 2 2009 2009 CD cord-280571-ntgt5hy9 89 3 Centers Centers NNPS cord-280571-ntgt5hy9 89 4 for for IN cord-280571-ntgt5hy9 89 5 Disease Disease NNP cord-280571-ntgt5hy9 89 6 Control Control NNP cord-280571-ntgt5hy9 89 7 and and CC cord-280571-ntgt5hy9 89 8 Prevention Prevention NNP cord-280571-ntgt5hy9 89 9 ( ( -LRB- cord-280571-ntgt5hy9 89 10 CDC CDC NNP cord-280571-ntgt5hy9 89 11 ) ) -RRB- cord-280571-ntgt5hy9 89 12 guidelines guideline NNS cord-280571-ntgt5hy9 89 13 recommend recommend VBP cord-280571-ntgt5hy9 89 14 that that IN cord-280571-ntgt5hy9 89 15 NAATs NAATs NNP cord-280571-ntgt5hy9 89 16 should should MD cord-280571-ntgt5hy9 89 17 be be VB cord-280571-ntgt5hy9 89 18 performed perform VBN cord-280571-ntgt5hy9 89 19 on on IN cord-280571-ntgt5hy9 89 20 at at RB cord-280571-ntgt5hy9 89 21 least least JJS cord-280571-ntgt5hy9 89 22 1 1 CD cord-280571-ntgt5hy9 89 23 respiratory respiratory JJ cord-280571-ntgt5hy9 89 24 sample sample NN cord-280571-ntgt5hy9 89 25 from from IN cord-280571-ntgt5hy9 89 26 patients patient NNS cord-280571-ntgt5hy9 89 27 with with IN cord-280571-ntgt5hy9 89 28 signs sign NNS cord-280571-ntgt5hy9 89 29 and and CC cord-280571-ntgt5hy9 89 30 symptoms symptom NNS cord-280571-ntgt5hy9 89 31 of of IN cord-280571-ntgt5hy9 89 32 pulmonary pulmonary JJ cord-280571-ntgt5hy9 89 33 M. M. NNP cord-280571-ntgt5hy9 89 34 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 89 35 colonization colonization NN cord-280571-ntgt5hy9 89 36 or or CC cord-280571-ntgt5hy9 89 37 infection infection NN cord-280571-ntgt5hy9 89 38 for for IN cord-280571-ntgt5hy9 89 39 whom whom WP cord-280571-ntgt5hy9 89 40 a a DT cord-280571-ntgt5hy9 89 41 diagnosis diagnosis NN cord-280571-ntgt5hy9 89 42 of of IN cord-280571-ntgt5hy9 89 43 M. M. NNP cord-280571-ntgt5hy9 89 44 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 89 45 colonization colonization NN cord-280571-ntgt5hy9 89 46 or or CC cord-280571-ntgt5hy9 89 47 infection infection NN cord-280571-ntgt5hy9 89 48 has have VBZ cord-280571-ntgt5hy9 89 49 not not RB cord-280571-ntgt5hy9 89 50 been be VBN cord-280571-ntgt5hy9 89 51 established establish VBN cord-280571-ntgt5hy9 89 52 or or CC cord-280571-ntgt5hy9 89 53 when when WRB cord-280571-ntgt5hy9 89 54 the the DT cord-280571-ntgt5hy9 89 55 results result NNS cord-280571-ntgt5hy9 89 56 would would MD cord-280571-ntgt5hy9 89 57 alter alter VB cord-280571-ntgt5hy9 89 58 case case NN cord-280571-ntgt5hy9 89 59 management management NN cord-280571-ntgt5hy9 89 60 or or CC cord-280571-ntgt5hy9 89 61 infection infection NN cord-280571-ntgt5hy9 89 62 control control NN cord-280571-ntgt5hy9 89 63 procedures procedure NNS cord-280571-ntgt5hy9 89 64 [ [ -LRB- cord-280571-ntgt5hy9 89 65 28 28 CD cord-280571-ntgt5hy9 89 66 ] ] -RRB- cord-280571-ntgt5hy9 89 67 . . . cord-280571-ntgt5hy9 90 1 Mycobacterial mycobacterial JJ cord-280571-ntgt5hy9 90 2 culture culture NN cord-280571-ntgt5hy9 90 3 is be VBZ cord-280571-ntgt5hy9 90 4 still still RB cord-280571-ntgt5hy9 90 5 required require VBN cord-280571-ntgt5hy9 90 6 , , , cord-280571-ntgt5hy9 90 7 because because IN cord-280571-ntgt5hy9 90 8 the the DT cord-280571-ntgt5hy9 90 9 M. M. NNP cord-280571-ntgt5hy9 90 10 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 90 11 isolate isolate VBP cord-280571-ntgt5hy9 90 12 is be VBZ cord-280571-ntgt5hy9 90 13 needed need VBN cord-280571-ntgt5hy9 90 14 for for IN cord-280571-ntgt5hy9 90 15 drug drug NN cord-280571-ntgt5hy9 90 16 susceptibility susceptibility NN cord-280571-ntgt5hy9 90 17 testing testing NN cord-280571-ntgt5hy9 90 18 . . . cord-280571-ntgt5hy9 91 1 Currently currently RB cord-280571-ntgt5hy9 91 2 , , , cord-280571-ntgt5hy9 91 3 there there EX cord-280571-ntgt5hy9 91 4 are be VBP cord-280571-ntgt5hy9 91 5 2 2 CD cord-280571-ntgt5hy9 91 6 FDA FDA NNP cord-280571-ntgt5hy9 91 7 - - HYPH cord-280571-ntgt5hy9 91 8 approved approve VBN cord-280571-ntgt5hy9 91 9 NAATs NAATs NNP cord-280571-ntgt5hy9 91 10 available available JJ cord-280571-ntgt5hy9 91 11 for for IN cord-280571-ntgt5hy9 91 12 the the DT cord-280571-ntgt5hy9 91 13 detection detection NN cord-280571-ntgt5hy9 91 14 of of IN cord-280571-ntgt5hy9 91 15 M. M. NNP cord-280571-ntgt5hy9 91 16 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 91 17 complex complex JJ cord-280571-ntgt5hy9 91 18 from from IN cord-280571-ntgt5hy9 91 19 respiratory respiratory JJ cord-280571-ntgt5hy9 91 20 samples sample NNS cord-280571-ntgt5hy9 91 21 , , , cord-280571-ntgt5hy9 91 22 the the DT cord-280571-ntgt5hy9 91 23 Amplified Amplified NNP cord-280571-ntgt5hy9 91 24 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 91 25 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 91 26 Direct direct JJ cord-280571-ntgt5hy9 91 27 Test test NN cord-280571-ntgt5hy9 91 28 ( ( -LRB- cord-280571-ntgt5hy9 91 29 AMTD AMTD NNP cord-280571-ntgt5hy9 91 30 , , , cord-280571-ntgt5hy9 91 31 Gen Gen NNP cord-280571-ntgt5hy9 91 32 - - HYPH cord-280571-ntgt5hy9 91 33 Probe Probe NNP cord-280571-ntgt5hy9 91 34 ) ) -RRB- cord-280571-ntgt5hy9 92 1 [ [ -LRB- cord-280571-ntgt5hy9 92 2 25 25 CD cord-280571-ntgt5hy9 92 3 , , , cord-280571-ntgt5hy9 92 4 [ [ -LRB- cord-280571-ntgt5hy9 92 5 29 29 CD cord-280571-ntgt5hy9 92 6 ] ] -RRB- cord-280571-ntgt5hy9 92 7 [ [ -LRB- cord-280571-ntgt5hy9 92 8 30 30 CD cord-280571-ntgt5hy9 92 9 ] ] -RRB- cord-280571-ntgt5hy9 92 10 [ [ -LRB- cord-280571-ntgt5hy9 92 11 31 31 CD cord-280571-ntgt5hy9 92 12 ] ] -RRB- cord-280571-ntgt5hy9 92 13 and and CC cord-280571-ntgt5hy9 92 14 the the DT cord-280571-ntgt5hy9 92 15 Amplicor Amplicor NNP cord-280571-ntgt5hy9 92 16 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 92 17 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 92 18 Test test NN cord-280571-ntgt5hy9 92 19 ( ( -LRB- cord-280571-ntgt5hy9 92 20 Amplicor Amplicor NNP cord-280571-ntgt5hy9 92 21 , , , cord-280571-ntgt5hy9 92 22 Roche Roche NNP cord-280571-ntgt5hy9 92 23 Diagnostics Diagnostics NNP cord-280571-ntgt5hy9 92 24 ) ) -RRB- cord-280571-ntgt5hy9 92 25 [ [ -LRB- cord-280571-ntgt5hy9 92 26 32 32 CD cord-280571-ntgt5hy9 92 27 ] ] -RRB- cord-280571-ntgt5hy9 92 28 [ [ -LRB- cord-280571-ntgt5hy9 92 29 33 33 CD cord-280571-ntgt5hy9 92 30 ] ] -RRB- cord-280571-ntgt5hy9 92 31 [ [ -LRB- cord-280571-ntgt5hy9 92 32 34 34 CD cord-280571-ntgt5hy9 92 33 ] ] -RRB- cord-280571-ntgt5hy9 92 34 [ [ -LRB- cord-280571-ntgt5hy9 92 35 35 35 CD cord-280571-ntgt5hy9 92 36 ] ] -RRB- cord-280571-ntgt5hy9 92 37 . . . cord-280571-ntgt5hy9 93 1 Recently recently RB cord-280571-ntgt5hy9 93 2 , , , cord-280571-ntgt5hy9 93 3 a a DT cord-280571-ntgt5hy9 93 4 new new JJ cord-280571-ntgt5hy9 93 5 assay assay NN cord-280571-ntgt5hy9 93 6 called call VBN cord-280571-ntgt5hy9 93 7 the the DT cord-280571-ntgt5hy9 93 8 Xpert Xpert NNP cord-280571-ntgt5hy9 93 9 MTB MTB NNP cord-280571-ntgt5hy9 93 10 / / SYM cord-280571-ntgt5hy9 93 11 RIF RIF NNP cord-280571-ntgt5hy9 93 12 ( ( -LRB- cord-280571-ntgt5hy9 93 13 Cepheid Cepheid NNP cord-280571-ntgt5hy9 93 14 ) ) -RRB- cord-280571-ntgt5hy9 93 15 was be VBD cord-280571-ntgt5hy9 93 16 developed develop VBN cord-280571-ntgt5hy9 93 17 to to TO cord-280571-ntgt5hy9 93 18 detect detect VB cord-280571-ntgt5hy9 93 19 the the DT cord-280571-ntgt5hy9 93 20 presence presence NN cord-280571-ntgt5hy9 93 21 of of IN cord-280571-ntgt5hy9 93 22 M. M. NNP cord-280571-ntgt5hy9 93 23 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 93 24 and and CC cord-280571-ntgt5hy9 93 25 rifampin rifampin NN cord-280571-ntgt5hy9 93 26 resistance resistance NN cord-280571-ntgt5hy9 93 27 directly directly RB cord-280571-ntgt5hy9 93 28 from from IN cord-280571-ntgt5hy9 93 29 processed process VBN cord-280571-ntgt5hy9 93 30 clinical clinical JJ cord-280571-ntgt5hy9 93 31 samples sample NNS cord-280571-ntgt5hy9 93 32 [ [ -LRB- cord-280571-ntgt5hy9 93 33 reviewed review VBN cord-280571-ntgt5hy9 93 34 in in IN cord-280571-ntgt5hy9 93 35 36 36 CD cord-280571-ntgt5hy9 93 36 ] ] -RRB- cord-280571-ntgt5hy9 93 37 . . . cord-280571-ntgt5hy9 94 1 The the DT cord-280571-ntgt5hy9 94 2 assay assay NN cord-280571-ntgt5hy9 94 3 uses use VBZ cord-280571-ntgt5hy9 94 4 a a DT cord-280571-ntgt5hy9 94 5 heminested heminested JJ cord-280571-ntgt5hy9 94 6 real real JJ cord-280571-ntgt5hy9 94 7 - - HYPH cord-280571-ntgt5hy9 94 8 time time NN cord-280571-ntgt5hy9 94 9 PCR PCR NNP cord-280571-ntgt5hy9 94 10 with with IN cord-280571-ntgt5hy9 94 11 molecular molecular JJ cord-280571-ntgt5hy9 94 12 beacon beacon NN cord-280571-ntgt5hy9 94 13 detection detection NN cord-280571-ntgt5hy9 94 14 and and CC cord-280571-ntgt5hy9 94 15 is be VBZ cord-280571-ntgt5hy9 94 16 performed perform VBN cord-280571-ntgt5hy9 94 17 on on IN cord-280571-ntgt5hy9 94 18 the the DT cord-280571-ntgt5hy9 94 19 GeneXpert GeneXpert NNP cord-280571-ntgt5hy9 94 20 instrument instrument NN cord-280571-ntgt5hy9 94 21 ( ( -LRB- cord-280571-ntgt5hy9 94 22 Cepheid Cepheid NNP cord-280571-ntgt5hy9 94 23 ) ) -RRB- cord-280571-ntgt5hy9 94 24 . . . cord-280571-ntgt5hy9 95 1 Benefits benefit NNS cord-280571-ntgt5hy9 95 2 of of IN cord-280571-ntgt5hy9 95 3 this this DT cord-280571-ntgt5hy9 95 4 assay assay NN cord-280571-ntgt5hy9 95 5 include include VBP cord-280571-ntgt5hy9 95 6 low low JJ cord-280571-ntgt5hy9 95 7 technical technical JJ cord-280571-ntgt5hy9 95 8 complexity complexity NN cord-280571-ntgt5hy9 95 9 , , , cord-280571-ntgt5hy9 95 10 allowing allow VBG cord-280571-ntgt5hy9 95 11 for for IN cord-280571-ntgt5hy9 95 12 potential potential JJ cord-280571-ntgt5hy9 95 13 point point NN cord-280571-ntgt5hy9 95 14 - - HYPH cord-280571-ntgt5hy9 95 15 of of IN cord-280571-ntgt5hy9 95 16 - - HYPH cord-280571-ntgt5hy9 95 17 care care NN cord-280571-ntgt5hy9 95 18 testing testing NN cord-280571-ntgt5hy9 95 19 ; ; : cord-280571-ntgt5hy9 95 20 minimal minimal JJ cord-280571-ntgt5hy9 95 21 hands hand NNS cord-280571-ntgt5hy9 95 22 - - HYPH cord-280571-ntgt5hy9 95 23 on on RP cord-280571-ntgt5hy9 95 24 time time NN cord-280571-ntgt5hy9 95 25 ( ( -LRB- cord-280571-ntgt5hy9 95 26 15 15 CD cord-280571-ntgt5hy9 95 27 - - SYM cord-280571-ntgt5hy9 95 28 20 20 CD cord-280571-ntgt5hy9 95 29 min min NN cord-280571-ntgt5hy9 95 30 ) ) -RRB- cord-280571-ntgt5hy9 95 31 ; ; : cord-280571-ntgt5hy9 95 32 test test VB cord-280571-ntgt5hy9 95 33 turnaround turnaround NN cord-280571-ntgt5hy9 95 34 time time NN cord-280571-ntgt5hy9 95 35 of of IN cord-280571-ntgt5hy9 95 36 , , , cord-280571-ntgt5hy9 95 37 2 2 CD cord-280571-ntgt5hy9 95 38 h h NN cord-280571-ntgt5hy9 95 39 ; ; : cord-280571-ntgt5hy9 95 40 and and CC cord-280571-ntgt5hy9 95 41 containment containment NN cord-280571-ntgt5hy9 95 42 of of IN cord-280571-ntgt5hy9 95 43 the the DT cord-280571-ntgt5hy9 95 44 sample sample NN cord-280571-ntgt5hy9 95 45 , , , cord-280571-ntgt5hy9 95 46 extracted extract VBN cord-280571-ntgt5hy9 95 47 nucleic nucleic JJ cord-280571-ntgt5hy9 95 48 acids acid NNS cord-280571-ntgt5hy9 95 49 , , , cord-280571-ntgt5hy9 95 50 and and CC cord-280571-ntgt5hy9 95 51 amplicons amplicon NNS cord-280571-ntgt5hy9 95 52 in in IN cord-280571-ntgt5hy9 95 53 the the DT cord-280571-ntgt5hy9 95 54 test test NN cord-280571-ntgt5hy9 95 55 cartridge cartridge NN cord-280571-ntgt5hy9 95 56 . . . cord-280571-ntgt5hy9 96 1 When when WRB cord-280571-ntgt5hy9 96 2 compared compare VBN cord-280571-ntgt5hy9 96 3 with with IN cord-280571-ntgt5hy9 96 4 culture culture NN cord-280571-ntgt5hy9 96 5 , , , cord-280571-ntgt5hy9 96 6 the the DT cord-280571-ntgt5hy9 96 7 sensitivity sensitivity NN cord-280571-ntgt5hy9 96 8 of of IN cord-280571-ntgt5hy9 96 9 the the DT cord-280571-ntgt5hy9 96 10 assay assay NN cord-280571-ntgt5hy9 96 11 for for IN cord-280571-ntgt5hy9 96 12 the the DT cord-280571-ntgt5hy9 96 13 detection detection NN cord-280571-ntgt5hy9 96 14 of of IN cord-280571-ntgt5hy9 96 15 M. M. NNP cord-280571-ntgt5hy9 96 16 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 96 17 ranged range VBD cord-280571-ntgt5hy9 96 18 from from IN cord-280571-ntgt5hy9 96 19 98.2 98.2 CD cord-280571-ntgt5hy9 96 20 % % NN cord-280571-ntgt5hy9 96 21 ( ( -LRB- cord-280571-ntgt5hy9 96 22 1 1 CD cord-280571-ntgt5hy9 96 23 sample sample NN cord-280571-ntgt5hy9 96 24 tested test VBN cord-280571-ntgt5hy9 96 25 per per IN cord-280571-ntgt5hy9 96 26 patient patient NN cord-280571-ntgt5hy9 96 27 ) ) -RRB- cord-280571-ntgt5hy9 96 28 to to IN cord-280571-ntgt5hy9 96 29 99.8 99.8 CD cord-280571-ntgt5hy9 96 30 % % NN cord-280571-ntgt5hy9 96 31 ( ( -LRB- cord-280571-ntgt5hy9 96 32 3 3 CD cord-280571-ntgt5hy9 96 33 samples sample NNS cord-280571-ntgt5hy9 96 34 tested test VBN cord-280571-ntgt5hy9 96 35 per per IN cord-280571-ntgt5hy9 96 36 patient patient NN cord-280571-ntgt5hy9 96 37 ) ) -RRB- cord-280571-ntgt5hy9 96 38 for for IN cord-280571-ntgt5hy9 96 39 AFB AFB NNP cord-280571-ntgt5hy9 96 40 smear smear NN cord-280571-ntgt5hy9 96 41 - - HYPH cord-280571-ntgt5hy9 96 42 positive positive JJ cord-280571-ntgt5hy9 96 43 samples sample NNS cord-280571-ntgt5hy9 96 44 and and CC cord-280571-ntgt5hy9 96 45 from from IN cord-280571-ntgt5hy9 96 46 72.5 72.5 CD cord-280571-ntgt5hy9 96 47 % % NN cord-280571-ntgt5hy9 96 48 ( ( -LRB- cord-280571-ntgt5hy9 96 49 1 1 CD cord-280571-ntgt5hy9 96 50 sample sample NN cord-280571-ntgt5hy9 96 51 tested test VBN cord-280571-ntgt5hy9 96 52 per per IN cord-280571-ntgt5hy9 96 53 patient patient NN cord-280571-ntgt5hy9 96 54 ) ) -RRB- cord-280571-ntgt5hy9 96 55 to to IN cord-280571-ntgt5hy9 96 56 90.2 90.2 CD cord-280571-ntgt5hy9 96 57 % % NN cord-280571-ntgt5hy9 96 58 ( ( -LRB- cord-280571-ntgt5hy9 96 59 3 3 CD cord-280571-ntgt5hy9 96 60 samples sample NNS cord-280571-ntgt5hy9 96 61 tested test VBN cord-280571-ntgt5hy9 96 62 per per IN cord-280571-ntgt5hy9 96 63 patient patient NN cord-280571-ntgt5hy9 96 64 ) ) -RRB- cord-280571-ntgt5hy9 96 65 for for IN cord-280571-ntgt5hy9 96 66 AFB AFB NNP cord-280571-ntgt5hy9 96 67 smear smear NN cord-280571-ntgt5hy9 96 68 - - HYPH cord-280571-ntgt5hy9 96 69 negative negative JJ cord-280571-ntgt5hy9 96 70 samples sample NNS cord-280571-ntgt5hy9 96 71 . . . cord-280571-ntgt5hy9 97 1 The the DT cord-280571-ntgt5hy9 97 2 specificity specificity NN cord-280571-ntgt5hy9 97 3 of of IN cord-280571-ntgt5hy9 97 4 the the DT cord-280571-ntgt5hy9 97 5 assay assay NN cord-280571-ntgt5hy9 97 6 ranged range VBD cord-280571-ntgt5hy9 97 7 from from IN cord-280571-ntgt5hy9 97 8 98.1 98.1 CD cord-280571-ntgt5hy9 97 9 % % NN cord-280571-ntgt5hy9 97 10 to to IN cord-280571-ntgt5hy9 97 11 99.2 99.2 CD cord-280571-ntgt5hy9 97 12 % % NN cord-280571-ntgt5hy9 97 13 . . . cord-280571-ntgt5hy9 98 1 The the DT cord-280571-ntgt5hy9 98 2 assay assay NN cord-280571-ntgt5hy9 98 3 is be VBZ cord-280571-ntgt5hy9 98 4 currently currently RB cord-280571-ntgt5hy9 98 5 available available JJ cord-280571-ntgt5hy9 98 6 for for IN cord-280571-ntgt5hy9 98 7 diagnostic diagnostic JJ cord-280571-ntgt5hy9 98 8 testing testing NN cord-280571-ntgt5hy9 98 9 only only RB cord-280571-ntgt5hy9 98 10 in in IN cord-280571-ntgt5hy9 98 11 Europe Europe NNP cord-280571-ntgt5hy9 98 12 . . . cord-280571-ntgt5hy9 99 1 Amplified amplify VBN cord-280571-ntgt5hy9 99 2 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 99 3 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 99 4 Direct direct JJ cord-280571-ntgt5hy9 99 5 Test test NN cord-280571-ntgt5hy9 99 6 ( ( -LRB- cord-280571-ntgt5hy9 99 7 AMTD AMTD NNP cord-280571-ntgt5hy9 99 8 , , , cord-280571-ntgt5hy9 99 9 Gen Gen NNP cord-280571-ntgt5hy9 99 10 - - HYPH cord-280571-ntgt5hy9 99 11 Probe Probe NNP cord-280571-ntgt5hy9 99 12 ) ) -RRB- cord-280571-ntgt5hy9 100 1 The the DT cord-280571-ntgt5hy9 100 2 AMTD AMTD NNP cord-280571-ntgt5hy9 100 3 is be VBZ cord-280571-ntgt5hy9 100 4 a a DT cord-280571-ntgt5hy9 100 5 target target NN cord-280571-ntgt5hy9 100 6 - - HYPH cord-280571-ntgt5hy9 100 7 amplified amplify VBN cord-280571-ntgt5hy9 100 8 nucleic nucleic JJ cord-280571-ntgt5hy9 100 9 acid acid NN cord-280571-ntgt5hy9 100 10 probe probe NN cord-280571-ntgt5hy9 100 11 test test NN cord-280571-ntgt5hy9 100 12 for for IN cord-280571-ntgt5hy9 100 13 the the DT cord-280571-ntgt5hy9 100 14 direct direct JJ cord-280571-ntgt5hy9 100 15 detection detection NN cord-280571-ntgt5hy9 100 16 of of IN cord-280571-ntgt5hy9 100 17 M. M. NNP cord-280571-ntgt5hy9 100 18 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 100 19 complex complex NN cord-280571-ntgt5hy9 100 20 ( ( -LRB- cord-280571-ntgt5hy9 100 21 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 100 22 bovis bovis NN cord-280571-ntgt5hy9 100 23 , , , cord-280571-ntgt5hy9 100 24 M. M. NNP cord-280571-ntgt5hy9 100 25 bovis bovis NN cord-280571-ntgt5hy9 100 26 BCG BCG NNP cord-280571-ntgt5hy9 100 27 , , , cord-280571-ntgt5hy9 100 28 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 100 29 africanum africanum NN cord-280571-ntgt5hy9 100 30 , , , cord-280571-ntgt5hy9 100 31 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 100 32 microti microti NN cord-280571-ntgt5hy9 100 33 , , , cord-280571-ntgt5hy9 100 34 and and CC cord-280571-ntgt5hy9 100 35 M. M. NNP cord-280571-ntgt5hy9 100 36 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 100 37 ) ) -RRB- cord-280571-ntgt5hy9 101 1 ribosomal ribosomal NNP cord-280571-ntgt5hy9 101 2 RNA RNA NNP cord-280571-ntgt5hy9 101 3 ( ( -LRB- cord-280571-ntgt5hy9 101 4 rRNA rrna NN cord-280571-ntgt5hy9 101 5 ) ) -RRB- cord-280571-ntgt5hy9 102 1 [ [ -LRB- cord-280571-ntgt5hy9 102 2 25 25 CD cord-280571-ntgt5hy9 102 3 , , , cord-280571-ntgt5hy9 102 4 [ [ -LRB- cord-280571-ntgt5hy9 102 5 29 29 CD cord-280571-ntgt5hy9 102 6 ] ] -RRB- cord-280571-ntgt5hy9 102 7 [ [ -LRB- cord-280571-ntgt5hy9 102 8 30 30 CD cord-280571-ntgt5hy9 102 9 ] ] -RRB- cord-280571-ntgt5hy9 102 10 [ [ -LRB- cord-280571-ntgt5hy9 102 11 31 31 CD cord-280571-ntgt5hy9 102 12 ] ] -RRB- cord-280571-ntgt5hy9 102 13 . . . cord-280571-ntgt5hy9 103 1 AMTD AMTD NNP cord-280571-ntgt5hy9 103 2 is be VBZ cord-280571-ntgt5hy9 103 3 approved approve VBN cord-280571-ntgt5hy9 103 4 for for IN cord-280571-ntgt5hy9 103 5 testing test VBG cord-280571-ntgt5hy9 103 6 both both DT cord-280571-ntgt5hy9 103 7 AFB AFB NNP cord-280571-ntgt5hy9 103 8 smear smear NN cord-280571-ntgt5hy9 103 9 - - HYPH cord-280571-ntgt5hy9 103 10 positive positive JJ cord-280571-ntgt5hy9 103 11 and and CC cord-280571-ntgt5hy9 103 12 smear smear JJ cord-280571-ntgt5hy9 103 13 - - HYPH cord-280571-ntgt5hy9 103 14 negative negative JJ cord-280571-ntgt5hy9 103 15 respiratory respiratory JJ cord-280571-ntgt5hy9 103 16 specimens specimen NNS cord-280571-ntgt5hy9 103 17 collected collect VBN cord-280571-ntgt5hy9 103 18 from from IN cord-280571-ntgt5hy9 103 19 patients patient NNS cord-280571-ntgt5hy9 103 20 suspected suspect VBN cord-280571-ntgt5hy9 103 21 of of IN cord-280571-ntgt5hy9 103 22 having have VBG cord-280571-ntgt5hy9 103 23 M. M. NNP cord-280571-ntgt5hy9 103 24 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 103 25 colonization colonization NN cord-280571-ntgt5hy9 103 26 or or CC cord-280571-ntgt5hy9 103 27 infection infection NN cord-280571-ntgt5hy9 103 28 . . . cord-280571-ntgt5hy9 104 1 The the DT cord-280571-ntgt5hy9 104 2 AMTD AMTD NNP cord-280571-ntgt5hy9 104 3 test test NN cord-280571-ntgt5hy9 104 4 is be VBZ cord-280571-ntgt5hy9 104 5 based base VBN cord-280571-ntgt5hy9 104 6 on on IN cord-280571-ntgt5hy9 104 7 isothermal isothermal JJ cord-280571-ntgt5hy9 104 8 ( ( -LRB- cord-280571-ntgt5hy9 104 9 42 42 CD cord-280571-ntgt5hy9 104 10 o o NN cord-280571-ntgt5hy9 104 11 C c NN cord-280571-ntgt5hy9 104 12 ) ) -RRB- cord-280571-ntgt5hy9 104 13 transcription transcription NN cord-280571-ntgt5hy9 104 14 - - HYPH cord-280571-ntgt5hy9 104 15 mediated mediate VBN cord-280571-ntgt5hy9 104 16 amplification amplification NN cord-280571-ntgt5hy9 104 17 that that WDT cord-280571-ntgt5hy9 104 18 uses use VBZ cord-280571-ntgt5hy9 104 19 2 2 CD cord-280571-ntgt5hy9 104 20 enzymes enzyme NNS cord-280571-ntgt5hy9 104 21 , , , cord-280571-ntgt5hy9 104 22 reverse reverse JJ cord-280571-ntgt5hy9 104 23 transcriptase transcriptase NN cord-280571-ntgt5hy9 104 24 ( ( -LRB- cord-280571-ntgt5hy9 104 25 RT RT NNP cord-280571-ntgt5hy9 104 26 ) ) -RRB- cord-280571-ntgt5hy9 104 27 and and CC cord-280571-ntgt5hy9 104 28 T7 T7 NNP cord-280571-ntgt5hy9 104 29 RNA RNA NNP cord-280571-ntgt5hy9 104 30 polymerase polymerase NN cord-280571-ntgt5hy9 104 31 , , , cord-280571-ntgt5hy9 104 32 and and CC cord-280571-ntgt5hy9 104 33 targetspecific targetspecific NN cord-280571-ntgt5hy9 104 34 primers primer NNS cord-280571-ntgt5hy9 104 35 . . . cord-280571-ntgt5hy9 105 1 A a DT cord-280571-ntgt5hy9 105 2 hybridization hybridization NN cord-280571-ntgt5hy9 105 3 protection protection NN cord-280571-ntgt5hy9 105 4 detection detection NN cord-280571-ntgt5hy9 105 5 assay assay NN cord-280571-ntgt5hy9 105 6 that that WDT cord-280571-ntgt5hy9 105 7 uses use VBZ cord-280571-ntgt5hy9 105 8 a a DT cord-280571-ntgt5hy9 105 9 chemiluminescent chemiluminescent NN cord-280571-ntgt5hy9 105 10 - - HYPH cord-280571-ntgt5hy9 105 11 labeled label VBN cord-280571-ntgt5hy9 105 12 , , , cord-280571-ntgt5hy9 105 13 single single RB cord-280571-ntgt5hy9 105 14 - - HYPH cord-280571-ntgt5hy9 105 15 stranded strand VBN cord-280571-ntgt5hy9 105 16 DNA dna NN cord-280571-ntgt5hy9 105 17 probe probe NN cord-280571-ntgt5hy9 105 18 complementary complementary JJ cord-280571-ntgt5hy9 105 19 to to IN cord-280571-ntgt5hy9 105 20 the the DT cord-280571-ntgt5hy9 105 21 M. M. NNP cord-280571-ntgt5hy9 105 22 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 105 23 complex complex JJ cord-280571-ntgt5hy9 105 24 - - HYPH cord-280571-ntgt5hy9 105 25 specific specific JJ cord-280571-ntgt5hy9 105 26 sequences sequence NNS cord-280571-ntgt5hy9 105 27 detects detect VBZ cord-280571-ntgt5hy9 105 28 the the DT cord-280571-ntgt5hy9 105 29 amplified amplify VBN cord-280571-ntgt5hy9 105 30 rRNA rrna NN cord-280571-ntgt5hy9 105 31 using use VBG cord-280571-ntgt5hy9 105 32 the the DT cord-280571-ntgt5hy9 105 33 Gen Gen NNP cord-280571-ntgt5hy9 105 34 - - HYPH cord-280571-ntgt5hy9 105 35 Probe Probe NNP cord-280571-ntgt5hy9 105 36 Leader Leader NNP cord-280571-ntgt5hy9 105 37 luminometer luminometer NN cord-280571-ntgt5hy9 105 38 . . . cord-280571-ntgt5hy9 106 1 Numerous numerous JJ cord-280571-ntgt5hy9 106 2 studies study NNS cord-280571-ntgt5hy9 106 3 have have VBP cord-280571-ntgt5hy9 106 4 evaluated evaluate VBN cord-280571-ntgt5hy9 106 5 AMTD AMTD NNP cord-280571-ntgt5hy9 106 6 and and CC cord-280571-ntgt5hy9 106 7 have have VBP cord-280571-ntgt5hy9 106 8 revealed reveal VBN cord-280571-ntgt5hy9 106 9 an an DT cord-280571-ntgt5hy9 106 10 average average JJ cord-280571-ntgt5hy9 106 11 sensitivity sensitivity NN cord-280571-ntgt5hy9 106 12 and and CC cord-280571-ntgt5hy9 106 13 specificity specificity NN cord-280571-ntgt5hy9 106 14 of of IN cord-280571-ntgt5hy9 106 15 .95 .95 CD cord-280571-ntgt5hy9 106 16 % % NN cord-280571-ntgt5hy9 106 17 and and CC cord-280571-ntgt5hy9 106 18 .98 .98 CD cord-280571-ntgt5hy9 106 19 % % NN cord-280571-ntgt5hy9 106 20 , , , cord-280571-ntgt5hy9 106 21 respectively respectively RB cord-280571-ntgt5hy9 106 22 , , , cord-280571-ntgt5hy9 106 23 for for IN cord-280571-ntgt5hy9 106 24 the the DT cord-280571-ntgt5hy9 106 25 detection detection NN cord-280571-ntgt5hy9 106 26 of of IN cord-280571-ntgt5hy9 106 27 M. M. NNP cord-280571-ntgt5hy9 106 28 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 106 29 complex complex NN cord-280571-ntgt5hy9 106 30 in in IN cord-280571-ntgt5hy9 106 31 smear smear NN cord-280571-ntgt5hy9 106 32 - - HYPH cord-280571-ntgt5hy9 106 33 positive positive JJ cord-280571-ntgt5hy9 106 34 respiratory respiratory JJ cord-280571-ntgt5hy9 106 35 samples sample NNS cord-280571-ntgt5hy9 106 36 and and CC cord-280571-ntgt5hy9 106 37 a a DT cord-280571-ntgt5hy9 106 38 sensitivity sensitivity NN cord-280571-ntgt5hy9 106 39 and and CC cord-280571-ntgt5hy9 106 40 specificity specificity NN cord-280571-ntgt5hy9 106 41 of of IN cord-280571-ntgt5hy9 106 42 .60 .60 CD cord-280571-ntgt5hy9 106 43 % % NN cord-280571-ntgt5hy9 106 44 and and CC cord-280571-ntgt5hy9 106 45 .72 .72 CD cord-280571-ntgt5hy9 106 46 % % NN cord-280571-ntgt5hy9 106 47 , , , cord-280571-ntgt5hy9 106 48 respectively respectively RB cord-280571-ntgt5hy9 106 49 , , , cord-280571-ntgt5hy9 106 50 for for IN cord-280571-ntgt5hy9 106 51 smear smear VB cord-280571-ntgt5hy9 106 52 - - HYPH cord-280571-ntgt5hy9 106 53 negative negative JJ cord-280571-ntgt5hy9 106 54 respiratory respiratory JJ cord-280571-ntgt5hy9 106 55 samples sample NNS cord-280571-ntgt5hy9 106 56 [ [ -LRB- cord-280571-ntgt5hy9 106 57 29 29 CD cord-280571-ntgt5hy9 106 58 ] ] -RRB- cord-280571-ntgt5hy9 106 59 [ [ -LRB- cord-280571-ntgt5hy9 106 60 30 30 CD cord-280571-ntgt5hy9 106 61 ] ] -RRB- cord-280571-ntgt5hy9 106 62 [ [ -LRB- cord-280571-ntgt5hy9 106 63 31 31 CD cord-280571-ntgt5hy9 106 64 ] ] -RRB- cord-280571-ntgt5hy9 106 65 . . . cord-280571-ntgt5hy9 107 1 Additional additional JJ cord-280571-ntgt5hy9 107 2 studies study NNS cord-280571-ntgt5hy9 107 3 have have VBP cord-280571-ntgt5hy9 107 4 evaluated evaluate VBN cord-280571-ntgt5hy9 107 5 the the DT cord-280571-ntgt5hy9 107 6 use use NN cord-280571-ntgt5hy9 107 7 of of IN cord-280571-ntgt5hy9 107 8 the the DT cord-280571-ntgt5hy9 107 9 test test NN cord-280571-ntgt5hy9 107 10 for for IN cord-280571-ntgt5hy9 107 11 several several JJ cord-280571-ntgt5hy9 107 12 types type NNS cord-280571-ntgt5hy9 107 13 of of IN cord-280571-ntgt5hy9 107 14 nonrespiratory nonrespiratory NN cord-280571-ntgt5hy9 107 15 samples sample NNS cord-280571-ntgt5hy9 107 16 , , , cord-280571-ntgt5hy9 107 17 such such JJ cord-280571-ntgt5hy9 107 18 as as IN cord-280571-ntgt5hy9 107 19 cerebrospinal cerebrospinal JJ cord-280571-ntgt5hy9 107 20 fluid fluid NN cord-280571-ntgt5hy9 107 21 and and CC cord-280571-ntgt5hy9 107 22 lymph lymph NN cord-280571-ntgt5hy9 107 23 nodes node NNS cord-280571-ntgt5hy9 107 24 [ [ -LRB- cord-280571-ntgt5hy9 107 25 29 29 CD cord-280571-ntgt5hy9 107 26 ] ] -RRB- cord-280571-ntgt5hy9 107 27 [ [ -LRB- cord-280571-ntgt5hy9 107 28 30 30 CD cord-280571-ntgt5hy9 107 29 ] ] -RRB- cord-280571-ntgt5hy9 107 30 [ [ -LRB- cord-280571-ntgt5hy9 107 31 31 31 CD cord-280571-ntgt5hy9 107 32 ] ] -RRB- cord-280571-ntgt5hy9 107 33 . . . cord-280571-ntgt5hy9 108 1 Amplicor Amplicor NNP cord-280571-ntgt5hy9 108 2 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 108 3 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 108 4 Test test NN cord-280571-ntgt5hy9 109 1 ( ( -LRB- cord-280571-ntgt5hy9 109 2 Amplicor Amplicor NNP cord-280571-ntgt5hy9 109 3 , , , cord-280571-ntgt5hy9 109 4 Roche Roche NNP cord-280571-ntgt5hy9 109 5 Diagnostics Diagnostics NNP cord-280571-ntgt5hy9 109 6 ) ) -RRB- cord-280571-ntgt5hy9 110 1 The the DT cord-280571-ntgt5hy9 110 2 Amplicor Amplicor NNP cord-280571-ntgt5hy9 110 3 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 110 4 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 110 5 test test NN cord-280571-ntgt5hy9 110 6 is be VBZ cord-280571-ntgt5hy9 110 7 FDA FDA NNP cord-280571-ntgt5hy9 110 8 approved approve VBN cord-280571-ntgt5hy9 110 9 for for IN cord-280571-ntgt5hy9 110 10 use use NN cord-280571-ntgt5hy9 110 11 with with IN cord-280571-ntgt5hy9 110 12 AFB AFB NNP cord-280571-ntgt5hy9 110 13 smear smear NN cord-280571-ntgt5hy9 110 14 - - HYPH cord-280571-ntgt5hy9 110 15 positive positive JJ cord-280571-ntgt5hy9 110 16 respiratory respiratory JJ cord-280571-ntgt5hy9 110 17 specimens specimen NNS cord-280571-ntgt5hy9 110 18 from from IN cord-280571-ntgt5hy9 110 19 patients patient NNS cord-280571-ntgt5hy9 110 20 suspected suspect VBN cord-280571-ntgt5hy9 110 21 of of IN cord-280571-ntgt5hy9 110 22 having have VBG cord-280571-ntgt5hy9 110 23 M. M. NNP cord-280571-ntgt5hy9 110 24 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 110 25 infection infection NN cord-280571-ntgt5hy9 110 26 or or CC cord-280571-ntgt5hy9 110 27 colonization colonization NN cord-280571-ntgt5hy9 110 28 [ [ -LRB- cord-280571-ntgt5hy9 110 29 32 32 CD cord-280571-ntgt5hy9 110 30 ] ] -RRB- cord-280571-ntgt5hy9 111 1 [ [ -LRB- cord-280571-ntgt5hy9 111 2 33 33 CD cord-280571-ntgt5hy9 111 3 ] ] -RRB- cord-280571-ntgt5hy9 112 1 [ [ -LRB- cord-280571-ntgt5hy9 112 2 34 34 CD cord-280571-ntgt5hy9 112 3 ] ] -RRB- cord-280571-ntgt5hy9 112 4 [ [ -LRB- cord-280571-ntgt5hy9 112 5 35 35 CD cord-280571-ntgt5hy9 112 6 ] ] -RRB- cord-280571-ntgt5hy9 112 7 . . . cord-280571-ntgt5hy9 113 1 The the DT cord-280571-ntgt5hy9 113 2 Amplicor Amplicor NNP cord-280571-ntgt5hy9 113 3 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 113 4 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 113 5 test test NN cord-280571-ntgt5hy9 113 6 uses use VBZ cord-280571-ntgt5hy9 113 7 traditional traditional JJ cord-280571-ntgt5hy9 113 8 PCR pcr NN cord-280571-ntgt5hy9 113 9 to to TO cord-280571-ntgt5hy9 113 10 amplify amplify VB cord-280571-ntgt5hy9 113 11 a a DT cord-280571-ntgt5hy9 113 12 region region NN cord-280571-ntgt5hy9 113 13 of of IN cord-280571-ntgt5hy9 113 14 the the DT cord-280571-ntgt5hy9 113 15 gene gene NN cord-280571-ntgt5hy9 113 16 encoding encode VBG cord-280571-ntgt5hy9 113 17 the the DT cord-280571-ntgt5hy9 113 18 16S 16S NNPS cord-280571-ntgt5hy9 113 19 rRNA rrna NN cord-280571-ntgt5hy9 113 20 of of IN cord-280571-ntgt5hy9 113 21 all all DT cord-280571-ntgt5hy9 113 22 mycobacteria mycobacterium NNS cord-280571-ntgt5hy9 113 23 . . . cord-280571-ntgt5hy9 114 1 Members member NNS cord-280571-ntgt5hy9 114 2 of of IN cord-280571-ntgt5hy9 114 3 the the DT cord-280571-ntgt5hy9 114 4 M. M. NNP cord-280571-ntgt5hy9 114 5 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 114 6 complex complex NN cord-280571-ntgt5hy9 114 7 are be VBP cord-280571-ntgt5hy9 114 8 identified identify VBN cord-280571-ntgt5hy9 114 9 after after IN cord-280571-ntgt5hy9 114 10 hybridization hybridization NN cord-280571-ntgt5hy9 114 11 with with IN cord-280571-ntgt5hy9 114 12 a a DT cord-280571-ntgt5hy9 114 13 DNA dna NN cord-280571-ntgt5hy9 114 14 target target NN cord-280571-ntgt5hy9 114 15 - - HYPH cord-280571-ntgt5hy9 114 16 specific specific JJ cord-280571-ntgt5hy9 114 17 probe probe NN cord-280571-ntgt5hy9 114 18 , , , cord-280571-ntgt5hy9 114 19 followed follow VBN cord-280571-ntgt5hy9 114 20 by by IN cord-280571-ntgt5hy9 114 21 substrate substrate JJ cord-280571-ntgt5hy9 114 22 addition addition NN cord-280571-ntgt5hy9 114 23 and and CC cord-280571-ntgt5hy9 114 24 colorimetric colorimetric JJ cord-280571-ntgt5hy9 114 25 detection detection NN cord-280571-ntgt5hy9 114 26 [ [ -LRB- cord-280571-ntgt5hy9 114 27 32 32 CD cord-280571-ntgt5hy9 114 28 ] ] -RRB- cord-280571-ntgt5hy9 114 29 . . . cord-280571-ntgt5hy9 115 1 When when WRB cord-280571-ntgt5hy9 115 2 testing test VBG cord-280571-ntgt5hy9 115 3 AFB AFB NNP cord-280571-ntgt5hy9 115 4 smear smear NN cord-280571-ntgt5hy9 115 5 - - HYPH cord-280571-ntgt5hy9 115 6 positive positive JJ cord-280571-ntgt5hy9 115 7 samples sample NNS cord-280571-ntgt5hy9 115 8 , , , cord-280571-ntgt5hy9 115 9 the the DT cord-280571-ntgt5hy9 115 10 Amplicor Amplicor NNP cord-280571-ntgt5hy9 115 11 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 115 12 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 115 13 test test NN cord-280571-ntgt5hy9 115 14 demonstrated demonstrate VBD cord-280571-ntgt5hy9 115 15 sensitivities sensitivity NNS cord-280571-ntgt5hy9 115 16 and and CC cord-280571-ntgt5hy9 115 17 specificities specificity NNS cord-280571-ntgt5hy9 115 18 for for IN cord-280571-ntgt5hy9 115 19 the the DT cord-280571-ntgt5hy9 115 20 detection detection NN cord-280571-ntgt5hy9 115 21 of of IN cord-280571-ntgt5hy9 115 22 M. M. NNP cord-280571-ntgt5hy9 115 23 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 115 24 complex complex NN cord-280571-ntgt5hy9 115 25 ranging range VBG cord-280571-ntgt5hy9 115 26 from from IN cord-280571-ntgt5hy9 115 27 92.9 92.9 CD cord-280571-ntgt5hy9 115 28 % % NN cord-280571-ntgt5hy9 115 29 to to IN cord-280571-ntgt5hy9 115 30 100 100 CD cord-280571-ntgt5hy9 115 31 % % NN cord-280571-ntgt5hy9 115 32 and and CC cord-280571-ntgt5hy9 115 33 from from IN cord-280571-ntgt5hy9 115 34 77.3 77.3 CD cord-280571-ntgt5hy9 115 35 % % NN cord-280571-ntgt5hy9 115 36 to to IN cord-280571-ntgt5hy9 115 37 100 100 CD cord-280571-ntgt5hy9 115 38 % % NN cord-280571-ntgt5hy9 115 39 , , , cord-280571-ntgt5hy9 115 40 respectively respectively RB cord-280571-ntgt5hy9 115 41 [ [ -LRB- cord-280571-ntgt5hy9 115 42 32 32 CD cord-280571-ntgt5hy9 115 43 , , , cord-280571-ntgt5hy9 115 44 33 33 CD cord-280571-ntgt5hy9 115 45 ] ] -RRB- cord-280571-ntgt5hy9 115 46 . . . cord-280571-ntgt5hy9 116 1 The the DT cord-280571-ntgt5hy9 116 2 sensitivities sensitivity NNS cord-280571-ntgt5hy9 116 3 and and CC cord-280571-ntgt5hy9 116 4 specificities specificity NNS cord-280571-ntgt5hy9 116 5 of of IN cord-280571-ntgt5hy9 116 6 Amplicor Amplicor NNP cord-280571-ntgt5hy9 116 7 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 116 8 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 116 9 for for IN cord-280571-ntgt5hy9 116 10 AFB AFB NNP cord-280571-ntgt5hy9 116 11 smear smear NN cord-280571-ntgt5hy9 116 12 - - HYPH cord-280571-ntgt5hy9 116 13 negative negative JJ cord-280571-ntgt5hy9 116 14 specimens specimen NNS cord-280571-ntgt5hy9 116 15 ranged range VBD cord-280571-ntgt5hy9 116 16 from from IN cord-280571-ntgt5hy9 116 17 51.2 51.2 CD cord-280571-ntgt5hy9 116 18 % % NN cord-280571-ntgt5hy9 116 19 to to IN cord-280571-ntgt5hy9 116 20 73.1 73.1 CD cord-280571-ntgt5hy9 116 21 % % NN cord-280571-ntgt5hy9 116 22 and and CC cord-280571-ntgt5hy9 116 23 99 99 CD cord-280571-ntgt5hy9 116 24 % % NN cord-280571-ntgt5hy9 116 25 to to IN cord-280571-ntgt5hy9 116 26 99.8 99.8 CD cord-280571-ntgt5hy9 116 27 % % NN cord-280571-ntgt5hy9 116 28 , , , cord-280571-ntgt5hy9 116 29 respectively respectively RB cord-280571-ntgt5hy9 116 30 [ [ -LRB- cord-280571-ntgt5hy9 116 31 32 32 CD cord-280571-ntgt5hy9 116 32 , , , cord-280571-ntgt5hy9 116 33 33 33 CD cord-280571-ntgt5hy9 116 34 ] ] -RRB- cord-280571-ntgt5hy9 116 35 . . . cord-280571-ntgt5hy9 117 1 The the DT cord-280571-ntgt5hy9 117 2 Amplicor Amplicor NNP cord-280571-ntgt5hy9 117 3 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 117 4 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 117 5 test test NN cord-280571-ntgt5hy9 117 6 has have VBZ cord-280571-ntgt5hy9 117 7 also also RB cord-280571-ntgt5hy9 117 8 been be VBN cord-280571-ntgt5hy9 117 9 evaluated evaluate VBN cord-280571-ntgt5hy9 117 10 for for IN cord-280571-ntgt5hy9 117 11 detection detection NN cord-280571-ntgt5hy9 117 12 of of IN cord-280571-ntgt5hy9 117 13 M. M. NNP cord-280571-ntgt5hy9 117 14 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 117 15 meningitis meningitis NN cord-280571-ntgt5hy9 117 16 [ [ -LRB- cord-280571-ntgt5hy9 117 17 34 34 CD cord-280571-ntgt5hy9 117 18 ] ] -RRB- cord-280571-ntgt5hy9 117 19 and and CC cord-280571-ntgt5hy9 117 20 for for IN cord-280571-ntgt5hy9 117 21 use use NN cord-280571-ntgt5hy9 117 22 with with IN cord-280571-ntgt5hy9 117 23 nonrespiratory nonrespiratory JJ cord-280571-ntgt5hy9 117 24 sample sample NN cord-280571-ntgt5hy9 117 25 types type NNS cord-280571-ntgt5hy9 117 26 [ [ -LRB- cord-280571-ntgt5hy9 117 27 35 35 CD cord-280571-ntgt5hy9 117 28 ] ] -RRB- cord-280571-ntgt5hy9 117 29 . . . cord-280571-ntgt5hy9 118 1 Viral viral JJ cord-280571-ntgt5hy9 118 2 respiratory respiratory JJ cord-280571-ntgt5hy9 118 3 pathogens pathogen NNS cord-280571-ntgt5hy9 118 4 are be VBP cord-280571-ntgt5hy9 118 5 particularly particularly RB cord-280571-ntgt5hy9 118 6 suited suit VBN cord-280571-ntgt5hy9 118 7 for for IN cord-280571-ntgt5hy9 118 8 detection detection NN cord-280571-ntgt5hy9 118 9 using use VBG cord-280571-ntgt5hy9 118 10 NAAT NAAT NNP cord-280571-ntgt5hy9 118 11 , , , cord-280571-ntgt5hy9 118 12 since since IN cord-280571-ntgt5hy9 118 13 the the DT cord-280571-ntgt5hy9 118 14 number number NN cord-280571-ntgt5hy9 118 15 of of IN cord-280571-ntgt5hy9 118 16 targets target NNS cord-280571-ntgt5hy9 118 17 is be VBZ cord-280571-ntgt5hy9 118 18 relatively relatively RB cord-280571-ntgt5hy9 118 19 limited limited JJ cord-280571-ntgt5hy9 118 20 , , , cord-280571-ntgt5hy9 118 21 compared compare VBN cord-280571-ntgt5hy9 118 22 with with IN cord-280571-ntgt5hy9 118 23 the the DT cord-280571-ntgt5hy9 118 24 numerous numerous JJ cord-280571-ntgt5hy9 118 25 potential potential JJ cord-280571-ntgt5hy9 118 26 bacterial bacterial JJ cord-280571-ntgt5hy9 118 27 pathogens pathogen NNS cord-280571-ntgt5hy9 118 28 that that WDT cord-280571-ntgt5hy9 118 29 can can MD cord-280571-ntgt5hy9 118 30 cause cause VB cord-280571-ntgt5hy9 118 31 respiratory respiratory JJ cord-280571-ntgt5hy9 118 32 disease disease NN cord-280571-ntgt5hy9 118 33 ( ( -LRB- cord-280571-ntgt5hy9 118 34 Table table NN cord-280571-ntgt5hy9 118 35 1 1 CD cord-280571-ntgt5hy9 118 36 ) ) -RRB- cord-280571-ntgt5hy9 118 37 . . . cord-280571-ntgt5hy9 119 1 Although although IN cord-280571-ntgt5hy9 119 2 there there EX cord-280571-ntgt5hy9 119 3 is be VBZ cord-280571-ntgt5hy9 119 4 much much JJ cord-280571-ntgt5hy9 119 5 to to TO cord-280571-ntgt5hy9 119 6 learn learn VB cord-280571-ntgt5hy9 119 7 regarding regard VBG cord-280571-ntgt5hy9 119 8 the the DT cord-280571-ntgt5hy9 119 9 clinical clinical JJ cord-280571-ntgt5hy9 119 10 relevance relevance NN cord-280571-ntgt5hy9 119 11 of of IN cord-280571-ntgt5hy9 119 12 mixed mixed JJ cord-280571-ntgt5hy9 119 13 viral viral JJ cord-280571-ntgt5hy9 119 14 respiratory respiratory JJ cord-280571-ntgt5hy9 119 15 infections infection NNS cord-280571-ntgt5hy9 119 16 , , , cord-280571-ntgt5hy9 119 17 the the DT cord-280571-ntgt5hy9 119 18 detection detection NN cord-280571-ntgt5hy9 119 19 of of IN cord-280571-ntgt5hy9 119 20 a a DT cord-280571-ntgt5hy9 119 21 respiratory respiratory JJ cord-280571-ntgt5hy9 119 22 virus virus NN cord-280571-ntgt5hy9 119 23 is be VBZ cord-280571-ntgt5hy9 119 24 generally generally RB cord-280571-ntgt5hy9 119 25 considered consider VBN cord-280571-ntgt5hy9 119 26 diagnostic diagnostic JJ cord-280571-ntgt5hy9 119 27 at at IN cord-280571-ntgt5hy9 119 28 this this DT cord-280571-ntgt5hy9 119 29 time time NN cord-280571-ntgt5hy9 119 30 . . . cord-280571-ntgt5hy9 120 1 Today today NN cord-280571-ntgt5hy9 120 2 , , , cord-280571-ntgt5hy9 120 3 most most JJS cord-280571-ntgt5hy9 120 4 laboratories laboratory NNS cord-280571-ntgt5hy9 120 5 do do VBP cord-280571-ntgt5hy9 120 6 not not RB cord-280571-ntgt5hy9 120 7 have have VB cord-280571-ntgt5hy9 120 8 the the DT cord-280571-ntgt5hy9 120 9 facilities facility NNS cord-280571-ntgt5hy9 120 10 for for IN cord-280571-ntgt5hy9 120 11 comprehensive comprehensive JJ cord-280571-ntgt5hy9 120 12 tissue tissue NN cord-280571-ntgt5hy9 120 13 culture culture NN cord-280571-ntgt5hy9 120 14 based base VBN cord-280571-ntgt5hy9 120 15 viral viral JJ cord-280571-ntgt5hy9 120 16 diagnostics diagnostic NNS cord-280571-ntgt5hy9 120 17 and and CC cord-280571-ntgt5hy9 120 18 therefore therefore RB cord-280571-ntgt5hy9 120 19 are be VBP cord-280571-ntgt5hy9 120 20 limited limit VBN cord-280571-ntgt5hy9 120 21 to to IN cord-280571-ntgt5hy9 120 22 testing test VBG cord-280571-ntgt5hy9 120 23 with with IN cord-280571-ntgt5hy9 120 24 less less RBR cord-280571-ntgt5hy9 120 25 sensitive sensitive JJ cord-280571-ntgt5hy9 120 26 and and CC cord-280571-ntgt5hy9 120 27 less less RBR cord-280571-ntgt5hy9 120 28 specific specific JJ cord-280571-ntgt5hy9 120 29 RADTs radt NNS cord-280571-ntgt5hy9 120 30 for for IN cord-280571-ntgt5hy9 120 31 only only JJ cord-280571-ntgt5hy9 120 32 influenza influenza NN cord-280571-ntgt5hy9 120 33 A a NN cord-280571-ntgt5hy9 120 34 , , , cord-280571-ntgt5hy9 120 35 influenza influenza NN cord-280571-ntgt5hy9 120 36 B b NN cord-280571-ntgt5hy9 120 37 , , , cord-280571-ntgt5hy9 120 38 and and CC cord-280571-ntgt5hy9 120 39 RSV RSV NNP cord-280571-ntgt5hy9 120 40 . . . cord-280571-ntgt5hy9 121 1 NAATS NAATS NNP cord-280571-ntgt5hy9 121 2 offer offer VBP cord-280571-ntgt5hy9 121 3 an an DT cord-280571-ntgt5hy9 121 4 excellent excellent JJ cord-280571-ntgt5hy9 121 5 alternative alternative NN cord-280571-ntgt5hy9 121 6 to to TO cord-280571-ntgt5hy9 121 7 greatly greatly RB cord-280571-ntgt5hy9 121 8 expand expand VB cord-280571-ntgt5hy9 121 9 the the DT cord-280571-ntgt5hy9 121 10 test test NN cord-280571-ntgt5hy9 121 11 menu menu NN cord-280571-ntgt5hy9 121 12 of of IN cord-280571-ntgt5hy9 121 13 clinical clinical JJ cord-280571-ntgt5hy9 121 14 laboratories laboratory NNS cord-280571-ntgt5hy9 121 15 , , , cord-280571-ntgt5hy9 121 16 thereby thereby RB cord-280571-ntgt5hy9 121 17 providing provide VBG cord-280571-ntgt5hy9 121 18 rapid rapid JJ cord-280571-ntgt5hy9 121 19 , , , cord-280571-ntgt5hy9 121 20 accurate accurate JJ cord-280571-ntgt5hy9 121 21 comprehensive comprehensive JJ cord-280571-ntgt5hy9 121 22 diagnostics diagnostic NNS cord-280571-ntgt5hy9 121 23 . . . cord-280571-ntgt5hy9 122 1 The the DT cord-280571-ntgt5hy9 122 2 first first JJ cord-280571-ntgt5hy9 122 3 multiplex multiplex NN cord-280571-ntgt5hy9 122 4 NAAT naat NN cord-280571-ntgt5hy9 122 5 to to TO cord-280571-ntgt5hy9 122 6 receive receive VB cord-280571-ntgt5hy9 122 7 clearance clearance NN cord-280571-ntgt5hy9 122 8 by by IN cord-280571-ntgt5hy9 122 9 the the DT cord-280571-ntgt5hy9 122 10 FDA FDA NNP cord-280571-ntgt5hy9 122 11 was be VBD cord-280571-ntgt5hy9 122 12 the the DT cord-280571-ntgt5hy9 122 13 xTAG xtag JJ cord-280571-ntgt5hy9 122 14 respiratory respiratory JJ cord-280571-ntgt5hy9 122 15 virus virus NN cord-280571-ntgt5hy9 122 16 panel panel NN cord-280571-ntgt5hy9 122 17 ( ( -LRB- cord-280571-ntgt5hy9 122 18 RVP RVP NNP cord-280571-ntgt5hy9 122 19 ) ) -RRB- cord-280571-ntgt5hy9 122 20 assay assay NN cord-280571-ntgt5hy9 122 21 in in IN cord-280571-ntgt5hy9 122 22 January January NNP cord-280571-ntgt5hy9 122 23 2008 2008 CD cord-280571-ntgt5hy9 122 24 . . . cord-280571-ntgt5hy9 123 1 The the DT cord-280571-ntgt5hy9 123 2 FDA FDA NNP cord-280571-ntgt5hy9 123 3 - - HYPH cord-280571-ntgt5hy9 123 4 approved approve VBN cord-280571-ntgt5hy9 123 5 version version NN cord-280571-ntgt5hy9 123 6 of of IN cord-280571-ntgt5hy9 123 7 RVP RVP NNP cord-280571-ntgt5hy9 123 8 detects detect VBZ cord-280571-ntgt5hy9 123 9 adenovirus adenovirus NN cord-280571-ntgt5hy9 123 10 , , , cord-280571-ntgt5hy9 123 11 influenza influenza NN cord-280571-ntgt5hy9 123 12 A a NN cord-280571-ntgt5hy9 123 13 ( ( -LRB- cord-280571-ntgt5hy9 123 14 with with IN cord-280571-ntgt5hy9 123 15 subtyping subtyping NN cord-280571-ntgt5hy9 123 16 of of IN cord-280571-ntgt5hy9 123 17 seasonal seasonal JJ cord-280571-ntgt5hy9 123 18 influenza influenza NN cord-280571-ntgt5hy9 123 19 A A NNP cord-280571-ntgt5hy9 123 20 / / SYM cord-280571-ntgt5hy9 123 21 H1 h1 NN cord-280571-ntgt5hy9 123 22 and and CC cord-280571-ntgt5hy9 123 23 seasonal seasonal JJ cord-280571-ntgt5hy9 123 24 influenza influenza NN cord-280571-ntgt5hy9 123 25 A A NNP cord-280571-ntgt5hy9 123 26 / / SYM cord-280571-ntgt5hy9 123 27 H3 H3 NNP cord-280571-ntgt5hy9 123 28 ) ) -RRB- cord-280571-ntgt5hy9 123 29 , , , cord-280571-ntgt5hy9 123 30 influenza influenza NN cord-280571-ntgt5hy9 123 31 B b NN cord-280571-ntgt5hy9 123 32 , , , cord-280571-ntgt5hy9 123 33 PIV-1 PIV-1 NNP cord-280571-ntgt5hy9 123 34 , , , cord-280571-ntgt5hy9 123 35 PIV-2 PIV-2 NNP cord-280571-ntgt5hy9 123 36 , , , cord-280571-ntgt5hy9 123 37 PIV-3 PIV-3 NNP cord-280571-ntgt5hy9 123 38 , , , cord-280571-ntgt5hy9 123 39 hMPV hmpv NN cord-280571-ntgt5hy9 123 40 , , , cord-280571-ntgt5hy9 123 41 rhinovirus rhinovirus NN cord-280571-ntgt5hy9 123 42 , , , cord-280571-ntgt5hy9 123 43 RSV RSV NNP cord-280571-ntgt5hy9 123 44 A A NNP cord-280571-ntgt5hy9 123 45 , , , cord-280571-ntgt5hy9 123 46 and and CC cord-280571-ntgt5hy9 123 47 RSV RSV NNP cord-280571-ntgt5hy9 123 48 B B NNP cord-280571-ntgt5hy9 123 49 [ [ -LRB- cord-280571-ntgt5hy9 123 50 37 37 CD cord-280571-ntgt5hy9 123 51 , , , cord-280571-ntgt5hy9 123 52 38 38 CD cord-280571-ntgt5hy9 123 53 ] ] -RRB- cord-280571-ntgt5hy9 123 54 . . . cord-280571-ntgt5hy9 124 1 The the DT cord-280571-ntgt5hy9 124 2 US US NNP cord-280571-ntgt5hy9 124 3 / / SYM cord-280571-ntgt5hy9 124 4 Canadian canadian JJ cord-280571-ntgt5hy9 124 5 research research NN cord-280571-ntgt5hy9 124 6 use use NN cord-280571-ntgt5hy9 124 7 - - HYPH cord-280571-ntgt5hy9 124 8 only only RB cord-280571-ntgt5hy9 124 9 version version NN cord-280571-ntgt5hy9 124 10 of of IN cord-280571-ntgt5hy9 124 11 the the DT cord-280571-ntgt5hy9 124 12 assay assay NN cord-280571-ntgt5hy9 124 13 also also RB cord-280571-ntgt5hy9 124 14 detects detect VBZ cord-280571-ntgt5hy9 124 15 4 4 CD cord-280571-ntgt5hy9 124 16 coronaviruses coronaviruse NNS cord-280571-ntgt5hy9 124 17 ( ( -LRB- cord-280571-ntgt5hy9 124 18 OC43 OC43 NNP cord-280571-ntgt5hy9 124 19 , , , cord-280571-ntgt5hy9 124 20 229E 229e CD cord-280571-ntgt5hy9 124 21 , , , cord-280571-ntgt5hy9 124 22 NL63 NL63 NNP cord-280571-ntgt5hy9 124 23 , , , cord-280571-ntgt5hy9 124 24 and and CC cord-280571-ntgt5hy9 124 25 HKU-1 HKU-1 NNP cord-280571-ntgt5hy9 124 26 ) ) -RRB- cord-280571-ntgt5hy9 124 27 , , , cord-280571-ntgt5hy9 124 28 parainfluenza parainfluenza NNP cord-280571-ntgt5hy9 124 29 type type NNP cord-280571-ntgt5hy9 124 30 4 4 CD cord-280571-ntgt5hy9 124 31 , , , cord-280571-ntgt5hy9 124 32 and and CC cord-280571-ntgt5hy9 124 33 enterovirus enterovirus NN cord-280571-ntgt5hy9 124 34 . . . cord-280571-ntgt5hy9 125 1 The the DT cord-280571-ntgt5hy9 125 2 test test NN cord-280571-ntgt5hy9 125 3 is be VBZ cord-280571-ntgt5hy9 125 4 approved approve VBN cord-280571-ntgt5hy9 125 5 for for IN cord-280571-ntgt5hy9 125 6 use use NN cord-280571-ntgt5hy9 125 7 with with IN cord-280571-ntgt5hy9 125 8 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 125 9 swab swab NN cord-280571-ntgt5hy9 125 10 samples sample NNS cord-280571-ntgt5hy9 125 11 collected collect VBN cord-280571-ntgt5hy9 125 12 from from IN cord-280571-ntgt5hy9 125 13 persons person NNS cord-280571-ntgt5hy9 125 14 symptomatic symptomatic JJ cord-280571-ntgt5hy9 125 15 for for IN cord-280571-ntgt5hy9 125 16 a a DT cord-280571-ntgt5hy9 125 17 respiratory respiratory JJ cord-280571-ntgt5hy9 125 18 virus virus NN cord-280571-ntgt5hy9 125 19 infection infection NN cord-280571-ntgt5hy9 125 20 and and CC cord-280571-ntgt5hy9 125 21 placed place VBN cord-280571-ntgt5hy9 125 22 in in IN cord-280571-ntgt5hy9 125 23 viral viral JJ cord-280571-ntgt5hy9 125 24 transport transport NN cord-280571-ntgt5hy9 125 25 media medium NNS cord-280571-ntgt5hy9 125 26 . . . cord-280571-ntgt5hy9 126 1 The the DT cord-280571-ntgt5hy9 126 2 xTAG xtag JJ cord-280571-ntgt5hy9 126 3 RVP RVP NNP cord-280571-ntgt5hy9 126 4 is be VBZ cord-280571-ntgt5hy9 126 5 a a DT cord-280571-ntgt5hy9 126 6 multistep multistep JJ cord-280571-ntgt5hy9 126 7 test test NN cord-280571-ntgt5hy9 126 8 that that WDT cord-280571-ntgt5hy9 126 9 takes take VBZ cord-280571-ntgt5hy9 126 10 approximately approximately RB cord-280571-ntgt5hy9 126 11 8 8 CD cord-280571-ntgt5hy9 126 12 - - SYM cord-280571-ntgt5hy9 126 13 10 10 CD cord-280571-ntgt5hy9 126 14 h h NN cord-280571-ntgt5hy9 126 15 to to TO cord-280571-ntgt5hy9 126 16 complete complete VB cord-280571-ntgt5hy9 126 17 , , , cord-280571-ntgt5hy9 126 18 depending depend VBG cord-280571-ntgt5hy9 126 19 on on IN cord-280571-ntgt5hy9 126 20 the the DT cord-280571-ntgt5hy9 126 21 number number NN cord-280571-ntgt5hy9 126 22 of of IN cord-280571-ntgt5hy9 126 23 samples sample NNS cord-280571-ntgt5hy9 126 24 to to TO cord-280571-ntgt5hy9 126 25 be be VB cord-280571-ntgt5hy9 126 26 tested test VBN cord-280571-ntgt5hy9 126 27 ( ( -LRB- cord-280571-ntgt5hy9 126 28 Figure figure NN cord-280571-ntgt5hy9 126 29 1 1 CD cord-280571-ntgt5hy9 126 30 ) ) -RRB- cord-280571-ntgt5hy9 126 31 . . . cord-280571-ntgt5hy9 127 1 Viral viral JJ cord-280571-ntgt5hy9 127 2 nucleic nucleic JJ cord-280571-ntgt5hy9 127 3 acid acid NN cord-280571-ntgt5hy9 127 4 and and CC cord-280571-ntgt5hy9 127 5 an an DT cord-280571-ntgt5hy9 127 6 internal internal JJ cord-280571-ntgt5hy9 127 7 control control NN cord-280571-ntgt5hy9 127 8 ( ( -LRB- cord-280571-ntgt5hy9 127 9 E. E. NNP cord-280571-ntgt5hy9 127 10 coli coli NNP cord-280571-ntgt5hy9 127 11 MS2 MS2 NNP cord-280571-ntgt5hy9 127 12 phage phage NN cord-280571-ntgt5hy9 127 13 ) ) -RRB- cord-280571-ntgt5hy9 127 14 are be VBP cord-280571-ntgt5hy9 127 15 coextracted coextracte VBN cord-280571-ntgt5hy9 127 16 from from IN cord-280571-ntgt5hy9 127 17 clinical clinical JJ cord-280571-ntgt5hy9 127 18 samples sample NNS cord-280571-ntgt5hy9 127 19 using use VBG cord-280571-ntgt5hy9 127 20 the the DT cord-280571-ntgt5hy9 127 21 QIAamp QIAamp NNP cord-280571-ntgt5hy9 127 22 MiniElute MiniElute NNP cord-280571-ntgt5hy9 127 23 ( ( -LRB- cord-280571-ntgt5hy9 127 24 Qiagen Qiagen NNP cord-280571-ntgt5hy9 127 25 ) ) -RRB- cord-280571-ntgt5hy9 127 26 , , , cord-280571-ntgt5hy9 127 27 the the DT cord-280571-ntgt5hy9 127 28 easyMAG easymag XX cord-280571-ntgt5hy9 127 29 ( ( -LRB- cord-280571-ntgt5hy9 127 30 bioMérieux bioMérieux NNP cord-280571-ntgt5hy9 127 31 ) ) -RRB- cord-280571-ntgt5hy9 127 32 , , , cord-280571-ntgt5hy9 127 33 or or CC cord-280571-ntgt5hy9 127 34 the the DT cord-280571-ntgt5hy9 127 35 miniMAG miniMAG NNS cord-280571-ntgt5hy9 127 36 ( ( -LRB- cord-280571-ntgt5hy9 127 37 bioMérieux bioMérieux NNP cord-280571-ntgt5hy9 127 38 ) ) -RRB- cord-280571-ntgt5hy9 127 39 extraction extraction NN cord-280571-ntgt5hy9 127 40 platforms platform NNS cord-280571-ntgt5hy9 127 41 . . . cord-280571-ntgt5hy9 128 1 A a DT cord-280571-ntgt5hy9 128 2 multiplex multiplex JJ cord-280571-ntgt5hy9 128 3 reverse reverse NN cord-280571-ntgt5hy9 128 4 transcription transcription NN cord-280571-ntgt5hy9 128 5 polymerase polymerase NN cord-280571-ntgt5hy9 128 6 chain chain NN cord-280571-ntgt5hy9 128 7 reaction reaction NN cord-280571-ntgt5hy9 128 8 ( ( -LRB- cord-280571-ntgt5hy9 128 9 RT RT NNP cord-280571-ntgt5hy9 128 10 - - HYPH cord-280571-ntgt5hy9 128 11 PCR PCR NNP cord-280571-ntgt5hy9 128 12 ) ) -RRB- cord-280571-ntgt5hy9 128 13 , , , cord-280571-ntgt5hy9 128 14 using use VBG cord-280571-ntgt5hy9 128 15 primer primer NN cord-280571-ntgt5hy9 128 16 sets set NNS cord-280571-ntgt5hy9 128 17 specific specific JJ cord-280571-ntgt5hy9 128 18 for for IN cord-280571-ntgt5hy9 128 19 the the DT cord-280571-ntgt5hy9 128 20 test test NN cord-280571-ntgt5hy9 128 21 targets target NNS cord-280571-ntgt5hy9 128 22 , , , cord-280571-ntgt5hy9 128 23 amplifies amplify VBZ cord-280571-ntgt5hy9 128 24 the the DT cord-280571-ntgt5hy9 128 25 viral viral JJ cord-280571-ntgt5hy9 128 26 nucleic nucleic JJ cord-280571-ntgt5hy9 128 27 acid acid NN cord-280571-ntgt5hy9 128 28 and and CC cord-280571-ntgt5hy9 128 29 internal internal JJ cord-280571-ntgt5hy9 128 30 control control NN cord-280571-ntgt5hy9 128 31 nucleic nucleic JJ cord-280571-ntgt5hy9 128 32 acid acid NN cord-280571-ntgt5hy9 128 33 . . . cord-280571-ntgt5hy9 129 1 PCR PCR NNP cord-280571-ntgt5hy9 129 2 products product NNS cord-280571-ntgt5hy9 129 3 are be VBP cord-280571-ntgt5hy9 129 4 treated treat VBN cord-280571-ntgt5hy9 129 5 with with IN cord-280571-ntgt5hy9 129 6 exonuclease exonuclease NN cord-280571-ntgt5hy9 129 7 I -PRON- PRP cord-280571-ntgt5hy9 129 8 to to TO cord-280571-ntgt5hy9 129 9 degrade degrade VB cord-280571-ntgt5hy9 129 10 any any DT cord-280571-ntgt5hy9 129 11 remaining remain VBG cord-280571-ntgt5hy9 129 12 primers primer NNS cord-280571-ntgt5hy9 129 13 and and CC cord-280571-ntgt5hy9 129 14 with with IN cord-280571-ntgt5hy9 129 15 shrimp shrimp NN cord-280571-ntgt5hy9 129 16 alkaline alkaline JJ cord-280571-ntgt5hy9 129 17 phosphatase phosphatase NN cord-280571-ntgt5hy9 129 18 to to TO cord-280571-ntgt5hy9 129 19 degrade degrade VB cord-280571-ntgt5hy9 129 20 any any DT cord-280571-ntgt5hy9 129 21 remaining remain VBG cord-280571-ntgt5hy9 129 22 nucleotides nucleotide NNS cord-280571-ntgt5hy9 129 23 . . . cord-280571-ntgt5hy9 130 1 The the DT cord-280571-ntgt5hy9 130 2 next next JJ cord-280571-ntgt5hy9 130 3 step step NN cord-280571-ntgt5hy9 130 4 consists consist VBZ cord-280571-ntgt5hy9 130 5 of of IN cord-280571-ntgt5hy9 130 6 target target NN cord-280571-ntgt5hy9 130 7 - - HYPH cord-280571-ntgt5hy9 130 8 specific specific JJ cord-280571-ntgt5hy9 130 9 primer primer NN cord-280571-ntgt5hy9 130 10 extension extension NN cord-280571-ntgt5hy9 130 11 ( ( -LRB- cord-280571-ntgt5hy9 130 12 TSPE TSPE NNP cord-280571-ntgt5hy9 130 13 ) ) -RRB- cord-280571-ntgt5hy9 130 14 . . . cord-280571-ntgt5hy9 131 1 When when WRB cord-280571-ntgt5hy9 131 2 a a DT cord-280571-ntgt5hy9 131 3 viral viral JJ cord-280571-ntgt5hy9 131 4 target(s target(s NNP cord-280571-ntgt5hy9 131 5 ) ) -RRB- cord-280571-ntgt5hy9 131 6 is be VBZ cord-280571-ntgt5hy9 131 7 present present JJ cord-280571-ntgt5hy9 131 8 , , , cord-280571-ntgt5hy9 131 9 the the DT cord-280571-ntgt5hy9 131 10 target target NN cord-280571-ntgt5hy9 131 11 - - HYPH cord-280571-ntgt5hy9 131 12 specific specific JJ cord-280571-ntgt5hy9 131 13 primer primer NN cord-280571-ntgt5hy9 131 14 ( ( -LRB- cord-280571-ntgt5hy9 131 15 containing contain VBG cord-280571-ntgt5hy9 131 16 a a DT cord-280571-ntgt5hy9 131 17 unique unique JJ cord-280571-ntgt5hy9 131 18 tag tag NN cord-280571-ntgt5hy9 131 19 sequence sequence NN cord-280571-ntgt5hy9 131 20 ) ) -RRB- cord-280571-ntgt5hy9 131 21 is be VBZ cord-280571-ntgt5hy9 131 22 extended extend VBN cord-280571-ntgt5hy9 131 23 and and CC cord-280571-ntgt5hy9 131 24 biotin biotin NN cord-280571-ntgt5hy9 131 25 - - HYPH cord-280571-ntgt5hy9 131 26 deoxycytidine deoxycytidine NN cord-280571-ntgt5hy9 131 27 triphosphate triphosphate NN cord-280571-ntgt5hy9 131 28 is be VBZ cord-280571-ntgt5hy9 131 29 incorporated incorporate VBN cord-280571-ntgt5hy9 131 30 into into IN cord-280571-ntgt5hy9 131 31 the the DT cord-280571-ntgt5hy9 131 32 extending extend VBG cord-280571-ntgt5hy9 131 33 chain chain NN cord-280571-ntgt5hy9 131 34 . . . cord-280571-ntgt5hy9 132 1 On on IN cord-280571-ntgt5hy9 132 2 completion completion NN cord-280571-ntgt5hy9 132 3 of of IN cord-280571-ntgt5hy9 132 4 the the DT cord-280571-ntgt5hy9 132 5 TSPE TSPE NNP cord-280571-ntgt5hy9 132 6 , , , cord-280571-ntgt5hy9 132 7 the the DT cord-280571-ntgt5hy9 132 8 detection detection NN cord-280571-ntgt5hy9 132 9 of of IN cord-280571-ntgt5hy9 132 10 amplified amplified JJ cord-280571-ntgt5hy9 132 11 products product NNS cord-280571-ntgt5hy9 132 12 is be VBZ cord-280571-ntgt5hy9 132 13 performed perform VBN cord-280571-ntgt5hy9 132 14 using use VBG cord-280571-ntgt5hy9 132 15 Luminex Luminex NNP cord-280571-ntgt5hy9 132 16 's 's POS cord-280571-ntgt5hy9 132 17 Universal Universal NNP cord-280571-ntgt5hy9 132 18 Tag Tag NNP cord-280571-ntgt5hy9 132 19 sorting sorting NN cord-280571-ntgt5hy9 132 20 system system NN cord-280571-ntgt5hy9 132 21 . . . cord-280571-ntgt5hy9 133 1 The the DT cord-280571-ntgt5hy9 133 2 TSPE TSPE NNP cord-280571-ntgt5hy9 133 3 reaction reaction NN cord-280571-ntgt5hy9 133 4 is be VBZ cord-280571-ntgt5hy9 133 5 added add VBN cord-280571-ntgt5hy9 133 6 directly directly RB cord-280571-ntgt5hy9 133 7 to to IN cord-280571-ntgt5hy9 133 8 microwells microwell NNS cord-280571-ntgt5hy9 133 9 containing contain VBG cord-280571-ntgt5hy9 133 10 spectrally spectrally RB cord-280571-ntgt5hy9 133 11 distinguishable distinguishable JJ cord-280571-ntgt5hy9 133 12 beads bead NNS cord-280571-ntgt5hy9 133 13 with with IN cord-280571-ntgt5hy9 133 14 antitags antitag NNS cord-280571-ntgt5hy9 133 15 , , , cord-280571-ntgt5hy9 133 16 which which WDT cord-280571-ntgt5hy9 133 17 are be VBP cord-280571-ntgt5hy9 133 18 complementary complementary JJ cord-280571-ntgt5hy9 133 19 to to IN cord-280571-ntgt5hy9 133 20 the the DT cord-280571-ntgt5hy9 133 21 sequence sequence NN cord-280571-ntgt5hy9 133 22 tags tag NNS cord-280571-ntgt5hy9 133 23 on on IN cord-280571-ntgt5hy9 133 24 the the DT cord-280571-ntgt5hy9 133 25 primers primer NNS cord-280571-ntgt5hy9 133 26 . . . cord-280571-ntgt5hy9 134 1 Each each DT cord-280571-ntgt5hy9 134 2 tagged tag VBN cord-280571-ntgt5hy9 134 3 primer primer NN cord-280571-ntgt5hy9 134 4 will will MD cord-280571-ntgt5hy9 134 5 hybridize hybridize VB cord-280571-ntgt5hy9 134 6 only only RB cord-280571-ntgt5hy9 134 7 to to IN cord-280571-ntgt5hy9 134 8 its -PRON- PRP$ cord-280571-ntgt5hy9 134 9 unique unique JJ cord-280571-ntgt5hy9 134 10 antitag antitag NN cord-280571-ntgt5hy9 134 11 complement complement NN cord-280571-ntgt5hy9 134 12 associated associate VBN cord-280571-ntgt5hy9 134 13 with with IN cord-280571-ntgt5hy9 134 14 a a DT cord-280571-ntgt5hy9 134 15 specific specific JJ cord-280571-ntgt5hy9 134 16 colored colored JJ cord-280571-ntgt5hy9 134 17 bead bead NN cord-280571-ntgt5hy9 134 18 . . . cord-280571-ntgt5hy9 135 1 A a DT cord-280571-ntgt5hy9 135 2 fluorescent fluorescent JJ cord-280571-ntgt5hy9 135 3 reporter reporter NN cord-280571-ntgt5hy9 135 4 molecule molecule NN cord-280571-ntgt5hy9 135 5 ( ( -LRB- cord-280571-ntgt5hy9 135 6 streptavidin streptavidin NNP cord-280571-ntgt5hy9 135 7 - - HYPH cord-280571-ntgt5hy9 135 8 phycoerythrin phycoerythrin NNP cord-280571-ntgt5hy9 135 9 ) ) -RRB- cord-280571-ntgt5hy9 135 10 will will MD cord-280571-ntgt5hy9 135 11 bind bind VB cord-280571-ntgt5hy9 135 12 to to IN cord-280571-ntgt5hy9 135 13 the the DT cord-280571-ntgt5hy9 135 14 biotin biotin NN cord-280571-ntgt5hy9 135 15 on on IN cord-280571-ntgt5hy9 135 16 the the DT cord-280571-ntgt5hy9 135 17 extended extended JJ cord-280571-ntgt5hy9 135 18 primers primer NNS cord-280571-ntgt5hy9 135 19 . . . cord-280571-ntgt5hy9 136 1 The the DT cord-280571-ntgt5hy9 136 2 beads bead NNS cord-280571-ntgt5hy9 136 3 are be VBP cord-280571-ntgt5hy9 136 4 then then RB cord-280571-ntgt5hy9 136 5 analyzed analyze VBN cord-280571-ntgt5hy9 136 6 with with IN cord-280571-ntgt5hy9 136 7 the the DT cord-280571-ntgt5hy9 136 8 Luminex Luminex NNP cord-280571-ntgt5hy9 136 9 xMAP xMAP HYPH cord-280571-ntgt5hy9 136 10 100/200 100/200 CD cord-280571-ntgt5hy9 136 11 instruments instrument NNS cord-280571-ntgt5hy9 136 12 . . . cord-280571-ntgt5hy9 137 1 Two two CD cord-280571-ntgt5hy9 137 2 lasers laser NNS cord-280571-ntgt5hy9 137 3 read read VBP cord-280571-ntgt5hy9 137 4 each each DT cord-280571-ntgt5hy9 137 5 bead bead NN cord-280571-ntgt5hy9 137 6 ; ; : cord-280571-ntgt5hy9 137 7 the the DT cord-280571-ntgt5hy9 137 8 first first JJ cord-280571-ntgt5hy9 137 9 identifies identify VBZ cord-280571-ntgt5hy9 137 10 the the DT cord-280571-ntgt5hy9 137 11 virus virus NN cord-280571-ntgt5hy9 137 12 - - HYPH cord-280571-ntgt5hy9 137 13 specific specific JJ cord-280571-ntgt5hy9 137 14 color color NN cord-280571-ntgt5hy9 137 15 - - HYPH cord-280571-ntgt5hy9 137 16 coded code VBN cord-280571-ntgt5hy9 137 17 bead bead NN cord-280571-ntgt5hy9 137 18 , , , cord-280571-ntgt5hy9 137 19 and and CC cord-280571-ntgt5hy9 137 20 the the DT cord-280571-ntgt5hy9 137 21 second second JJ cord-280571-ntgt5hy9 137 22 determines determine VBZ cord-280571-ntgt5hy9 137 23 whether whether IN cord-280571-ntgt5hy9 137 24 an an DT cord-280571-ntgt5hy9 137 25 amplicon amplicon NN cord-280571-ntgt5hy9 137 26 is be VBZ cord-280571-ntgt5hy9 137 27 hybridized hybridize VBN cord-280571-ntgt5hy9 137 28 to to IN cord-280571-ntgt5hy9 137 29 the the DT cord-280571-ntgt5hy9 137 30 bead bead NN cord-280571-ntgt5hy9 137 31 on on IN cord-280571-ntgt5hy9 137 32 the the DT cord-280571-ntgt5hy9 137 33 basis basis NN cord-280571-ntgt5hy9 137 34 of of IN cord-280571-ntgt5hy9 137 35 the the DT cord-280571-ntgt5hy9 137 36 detection detection NN cord-280571-ntgt5hy9 137 37 of of IN cord-280571-ntgt5hy9 137 38 fluorescence fluorescence NN cord-280571-ntgt5hy9 137 39 ( ( -LRB- cord-280571-ntgt5hy9 137 40 mean mean VB cord-280571-ntgt5hy9 137 41 fluorescence fluorescence NN cord-280571-ntgt5hy9 137 42 intensities intensity NNS cord-280571-ntgt5hy9 137 43 [ [ -LRB- cord-280571-ntgt5hy9 137 44 MFIs mfi NNS cord-280571-ntgt5hy9 137 45 ] ] -RRB- cord-280571-ntgt5hy9 137 46 ) ) -RRB- cord-280571-ntgt5hy9 137 47 above above IN cord-280571-ntgt5hy9 137 48 a a DT cord-280571-ntgt5hy9 137 49 background background NN cord-280571-ntgt5hy9 137 50 threshold threshold NN cord-280571-ntgt5hy9 137 51 . . . cord-280571-ntgt5hy9 138 1 The the DT cord-280571-ntgt5hy9 138 2 clinical clinical JJ cord-280571-ntgt5hy9 138 3 performance performance NN cord-280571-ntgt5hy9 138 4 characteristics characteristic NNS cord-280571-ntgt5hy9 138 5 of of IN cord-280571-ntgt5hy9 138 6 the the DT cord-280571-ntgt5hy9 138 7 xTAG xtag JJ cord-280571-ntgt5hy9 138 8 RVP RVP NNP cord-280571-ntgt5hy9 138 9 assay assay NN cord-280571-ntgt5hy9 138 10 were be VBD cord-280571-ntgt5hy9 138 11 established establish VBN cord-280571-ntgt5hy9 138 12 by by IN cord-280571-ntgt5hy9 138 13 the the DT cord-280571-ntgt5hy9 138 14 manufacturer manufacturer NN cord-280571-ntgt5hy9 138 15 through through IN cord-280571-ntgt5hy9 138 16 prospectively prospectively RB cord-280571-ntgt5hy9 138 17 collected collect VBN cord-280571-ntgt5hy9 138 18 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 138 19 swab swab NN cord-280571-ntgt5hy9 138 20 samples sample NNS cord-280571-ntgt5hy9 138 21 ( ( -LRB- cord-280571-ntgt5hy9 138 22 n n NN cord-280571-ntgt5hy9 138 23 5 5 CD cord-280571-ntgt5hy9 138 24 544 544 CD cord-280571-ntgt5hy9 138 25 ) ) -RRB- cord-280571-ntgt5hy9 138 26 tested test VBD cord-280571-ntgt5hy9 138 27 during during IN cord-280571-ntgt5hy9 138 28 the the DT cord-280571-ntgt5hy9 138 29 2005 2005 CD cord-280571-ntgt5hy9 138 30 - - SYM cord-280571-ntgt5hy9 138 31 2006 2006 CD cord-280571-ntgt5hy9 138 32 influenza influenza NN cord-280571-ntgt5hy9 138 33 season season NN cord-280571-ntgt5hy9 138 34 at at IN cord-280571-ntgt5hy9 138 35 4 4 CD cord-280571-ntgt5hy9 138 36 North north JJ cord-280571-ntgt5hy9 138 37 American american JJ cord-280571-ntgt5hy9 138 38 clinical clinical JJ cord-280571-ntgt5hy9 138 39 laboratories laboratory NNS cord-280571-ntgt5hy9 138 40 [ [ -LRB- cord-280571-ntgt5hy9 138 41 101 101 CD cord-280571-ntgt5hy9 138 42 ] ] -RRB- cord-280571-ntgt5hy9 138 43 . . . cord-280571-ntgt5hy9 139 1 All all DT cord-280571-ntgt5hy9 139 2 specimens specimen NNS cord-280571-ntgt5hy9 139 3 were be VBD cord-280571-ntgt5hy9 139 4 tested test VBN cord-280571-ntgt5hy9 139 5 by by IN cord-280571-ntgt5hy9 139 6 means mean NNS cord-280571-ntgt5hy9 139 7 of of IN cord-280571-ntgt5hy9 139 8 viral viral JJ cord-280571-ntgt5hy9 139 9 culture culture NN cord-280571-ntgt5hy9 139 10 and/or and/or CC cord-280571-ntgt5hy9 140 1 DFA DFA NNP cord-280571-ntgt5hy9 140 2 testing testing NN cord-280571-ntgt5hy9 140 3 for for IN cord-280571-ntgt5hy9 140 4 the the DT cord-280571-ntgt5hy9 140 5 following follow VBG cord-280571-ntgt5hy9 140 6 targets target NNS cord-280571-ntgt5hy9 140 7 : : : cord-280571-ntgt5hy9 140 8 influenza influenza NN cord-280571-ntgt5hy9 140 9 A A NNP cord-280571-ntgt5hy9 140 10 , , , cord-280571-ntgt5hy9 140 11 influenza influenza NN cord-280571-ntgt5hy9 140 12 B b NN cord-280571-ntgt5hy9 140 13 , , , cord-280571-ntgt5hy9 140 14 RSV RSV NNP cord-280571-ntgt5hy9 140 15 , , , cord-280571-ntgt5hy9 140 16 PIV-1 PIV-1 NNP cord-280571-ntgt5hy9 140 17 , , , cord-280571-ntgt5hy9 140 18 PIV-2 PIV-2 NNP cord-280571-ntgt5hy9 140 19 , , , cord-280571-ntgt5hy9 140 20 PIV-3 PIV-3 NNP cord-280571-ntgt5hy9 140 21 , , , cord-280571-ntgt5hy9 140 22 and and CC cord-280571-ntgt5hy9 140 23 adenovirus adenovirus NN cord-280571-ntgt5hy9 140 24 . . . cord-280571-ntgt5hy9 141 1 The the DT cord-280571-ntgt5hy9 141 2 comparator comparator NN cord-280571-ntgt5hy9 141 3 methods method NNS cord-280571-ntgt5hy9 141 4 for for IN cord-280571-ntgt5hy9 141 5 influenza influenza NN cord-280571-ntgt5hy9 141 6 A a DT cord-280571-ntgt5hy9 141 7 subtyping subtyping NN cord-280571-ntgt5hy9 141 8 , , , cord-280571-ntgt5hy9 141 9 RSV RSV NNP cord-280571-ntgt5hy9 141 10 subtyping subtyping NN cord-280571-ntgt5hy9 141 11 , , , cord-280571-ntgt5hy9 141 12 and and CC cord-280571-ntgt5hy9 141 13 hMPV hmpv NN cord-280571-ntgt5hy9 141 14 and and CC cord-280571-ntgt5hy9 141 15 rhinovirus rhinovirus NN cord-280571-ntgt5hy9 141 16 detection detection NN cord-280571-ntgt5hy9 141 17 were be VBD cord-280571-ntgt5hy9 141 18 wellcharacterized wellcharacterize VBN cord-280571-ntgt5hy9 141 19 RT RT NNP cord-280571-ntgt5hy9 141 20 - - HYPH cord-280571-ntgt5hy9 141 21 PCR PCR NNP cord-280571-ntgt5hy9 141 22 assays assay NNS cord-280571-ntgt5hy9 141 23 followed follow VBN cord-280571-ntgt5hy9 141 24 by by IN cord-280571-ntgt5hy9 141 25 bidirectional bidirectional JJ cord-280571-ntgt5hy9 141 26 sequencing sequencing NN cord-280571-ntgt5hy9 141 27 . . . cord-280571-ntgt5hy9 142 1 xTAG xTAG NNP cord-280571-ntgt5hy9 143 1 RVP RVP NNP cord-280571-ntgt5hy9 143 2 sensitivity sensitivity NN cord-280571-ntgt5hy9 143 3 for for IN cord-280571-ntgt5hy9 143 4 each each DT cord-280571-ntgt5hy9 143 5 target target NN cord-280571-ntgt5hy9 143 6 was be VBD cord-280571-ntgt5hy9 143 7 determined determine VBN cord-280571-ntgt5hy9 143 8 as as IN cord-280571-ntgt5hy9 143 9 follows follow VBZ cord-280571-ntgt5hy9 143 10 : : : cord-280571-ntgt5hy9 144 1 The the DT cord-280571-ntgt5hy9 144 2 benefits benefit NNS cord-280571-ntgt5hy9 144 3 of of IN cord-280571-ntgt5hy9 144 4 the the DT cord-280571-ntgt5hy9 144 5 xTAG xtag JJ cord-280571-ntgt5hy9 144 6 RVP RVP NNP cord-280571-ntgt5hy9 144 7 assay assay NN cord-280571-ntgt5hy9 144 8 include include VBP cord-280571-ntgt5hy9 144 9 the the DT cord-280571-ntgt5hy9 144 10 broad broad JJ cord-280571-ntgt5hy9 144 11 spectrum spectrum NN cord-280571-ntgt5hy9 144 12 of of IN cord-280571-ntgt5hy9 144 13 viruses virus NNS cord-280571-ntgt5hy9 144 14 detected detect VBN cord-280571-ntgt5hy9 144 15 by by IN cord-280571-ntgt5hy9 144 16 a a DT cord-280571-ntgt5hy9 144 17 single single JJ cord-280571-ntgt5hy9 144 18 test test NN cord-280571-ntgt5hy9 144 19 , , , cord-280571-ntgt5hy9 144 20 with with IN cord-280571-ntgt5hy9 144 21 a a DT cord-280571-ntgt5hy9 144 22 cost cost NN cord-280571-ntgt5hy9 144 23 per per IN cord-280571-ntgt5hy9 144 24 test test NN cord-280571-ntgt5hy9 144 25 comparable comparable JJ cord-280571-ntgt5hy9 144 26 to to IN cord-280571-ntgt5hy9 144 27 real real JJ cord-280571-ntgt5hy9 144 28 - - HYPH cord-280571-ntgt5hy9 144 29 time time NN cord-280571-ntgt5hy9 144 30 assays assay NNS cord-280571-ntgt5hy9 144 31 that that WDT cord-280571-ntgt5hy9 144 32 only only RB cord-280571-ntgt5hy9 144 33 target target VBP cord-280571-ntgt5hy9 144 34 up up IN cord-280571-ntgt5hy9 144 35 to to TO cord-280571-ntgt5hy9 144 36 3 3 CD cord-280571-ntgt5hy9 144 37 analytes analyte NNS cord-280571-ntgt5hy9 144 38 . . . cord-280571-ntgt5hy9 145 1 The the DT cord-280571-ntgt5hy9 145 2 subtyping subtyping NN cord-280571-ntgt5hy9 145 3 of of IN cord-280571-ntgt5hy9 145 4 influenza influenza NN cord-280571-ntgt5hy9 145 5 A a DT cord-280571-ntgt5hy9 145 6 viruses virus NNS cord-280571-ntgt5hy9 145 7 as as IN cord-280571-ntgt5hy9 145 8 seasonal seasonal JJ cord-280571-ntgt5hy9 145 9 influenza influenza NN cord-280571-ntgt5hy9 145 10 A A NNP cord-280571-ntgt5hy9 145 11 / / SYM cord-280571-ntgt5hy9 145 12 H1 h1 NN cord-280571-ntgt5hy9 145 13 or or CC cord-280571-ntgt5hy9 145 14 seasonal seasonal JJ cord-280571-ntgt5hy9 145 15 influenza influenza NN cord-280571-ntgt5hy9 145 16 A A NNP cord-280571-ntgt5hy9 145 17 / / SYM cord-280571-ntgt5hy9 145 18 H3 H3 NNP cord-280571-ntgt5hy9 145 19 or or CC cord-280571-ntgt5hy9 145 20 the the DT cord-280571-ntgt5hy9 145 21 identification identification NN cord-280571-ntgt5hy9 145 22 of of IN cord-280571-ntgt5hy9 145 23 an an DT cord-280571-ntgt5hy9 145 24 ' ' '' cord-280571-ntgt5hy9 145 25 ' ' `` cord-280571-ntgt5hy9 145 26 unsubtypeable unsubtypeable JJ cord-280571-ntgt5hy9 145 27 ' ' '' cord-280571-ntgt5hy9 145 28 ' ' '' cord-280571-ntgt5hy9 145 29 virus virus NN cord-280571-ntgt5hy9 145 30 has have VBZ cord-280571-ntgt5hy9 145 31 proven prove VBN cord-280571-ntgt5hy9 145 32 to to TO cord-280571-ntgt5hy9 145 33 be be VB cord-280571-ntgt5hy9 145 34 an an DT cord-280571-ntgt5hy9 145 35 important important JJ cord-280571-ntgt5hy9 145 36 aid aid NN cord-280571-ntgt5hy9 145 37 in in IN cord-280571-ntgt5hy9 145 38 identifying identify VBG cord-280571-ntgt5hy9 145 39 novel novel NN cord-280571-ntgt5hy9 145 40 influenza influenza NN cord-280571-ntgt5hy9 145 41 A a DT cord-280571-ntgt5hy9 145 42 strains strain NNS cord-280571-ntgt5hy9 145 43 . . . cord-280571-ntgt5hy9 146 1 A a DT cord-280571-ntgt5hy9 146 2 limitation limitation NN cord-280571-ntgt5hy9 146 3 of of IN cord-280571-ntgt5hy9 146 4 the the DT cord-280571-ntgt5hy9 146 5 assay assay NN cord-280571-ntgt5hy9 146 6 is be VBZ cord-280571-ntgt5hy9 146 7 the the DT cord-280571-ntgt5hy9 146 8 decreased decrease VBN cord-280571-ntgt5hy9 146 9 sensitivity sensitivity NN cord-280571-ntgt5hy9 146 10 for for IN cord-280571-ntgt5hy9 146 11 the the DT cord-280571-ntgt5hy9 146 12 detection detection NN cord-280571-ntgt5hy9 146 13 of of IN cord-280571-ntgt5hy9 146 14 certain certain JJ cord-280571-ntgt5hy9 146 15 adenovirus adenovirus NN cord-280571-ntgt5hy9 146 16 strains strain NNS cord-280571-ntgt5hy9 146 17 . . . cord-280571-ntgt5hy9 147 1 In in IN cord-280571-ntgt5hy9 147 2 - - HYPH cord-280571-ntgt5hy9 147 3 house house NN cord-280571-ntgt5hy9 147 4 validation validation NN cord-280571-ntgt5hy9 147 5 studies study NNS cord-280571-ntgt5hy9 147 6 by by IN cord-280571-ntgt5hy9 147 7 our -PRON- PRP$ cord-280571-ntgt5hy9 147 8 laboratory laboratory NN cord-280571-ntgt5hy9 147 9 have have VBP cord-280571-ntgt5hy9 147 10 found find VBN cord-280571-ntgt5hy9 147 11 that that IN cord-280571-ntgt5hy9 147 12 by by IN cord-280571-ntgt5hy9 147 13 reducing reduce VBG cord-280571-ntgt5hy9 147 14 the the DT cord-280571-ntgt5hy9 147 15 positive positive JJ cord-280571-ntgt5hy9 147 16 cutoff cutoff NN cord-280571-ntgt5hy9 147 17 MFI mfi NN cord-280571-ntgt5hy9 147 18 level level NN cord-280571-ntgt5hy9 147 19 from from IN cord-280571-ntgt5hy9 147 20 300 300 CD cord-280571-ntgt5hy9 147 21 to to TO cord-280571-ntgt5hy9 147 22 150 150 CD cord-280571-ntgt5hy9 147 23 for for IN cord-280571-ntgt5hy9 147 24 adenovirus adenovirus NN cord-280571-ntgt5hy9 147 25 , , , cord-280571-ntgt5hy9 147 26 improved improve VBN cord-280571-ntgt5hy9 147 27 sensitivity sensitivity NN cord-280571-ntgt5hy9 147 28 for for IN cord-280571-ntgt5hy9 147 29 the the DT cord-280571-ntgt5hy9 147 30 detection detection NN cord-280571-ntgt5hy9 147 31 of of IN cord-280571-ntgt5hy9 147 32 adenovirus adenovirus NN cord-280571-ntgt5hy9 147 33 was be VBD cord-280571-ntgt5hy9 147 34 obtained obtain VBN cord-280571-ntgt5hy9 147 35 without without IN cord-280571-ntgt5hy9 147 36 loss loss NN cord-280571-ntgt5hy9 147 37 of of IN cord-280571-ntgt5hy9 147 38 specificity specificity NN cord-280571-ntgt5hy9 147 39 ( ( -LRB- cord-280571-ntgt5hy9 147 40 unpublished unpublished JJ cord-280571-ntgt5hy9 147 41 data datum NNS cord-280571-ntgt5hy9 147 42 ) ) -RRB- cord-280571-ntgt5hy9 147 43 . . . cord-280571-ntgt5hy9 148 1 Additional additional JJ cord-280571-ntgt5hy9 148 2 limitations limitation NNS cord-280571-ntgt5hy9 148 3 of of IN cord-280571-ntgt5hy9 148 4 the the DT cord-280571-ntgt5hy9 148 5 assay assay NN cord-280571-ntgt5hy9 148 6 include include VBP cord-280571-ntgt5hy9 148 7 the the DT cord-280571-ntgt5hy9 148 8 time time NN cord-280571-ntgt5hy9 148 9 to to IN cord-280571-ntgt5hy9 148 10 final final JJ cord-280571-ntgt5hy9 148 11 results result NNS cord-280571-ntgt5hy9 148 12 , , , cord-280571-ntgt5hy9 148 13 number number NN cord-280571-ntgt5hy9 148 14 of of IN cord-280571-ntgt5hy9 148 15 required require VBN cord-280571-ntgt5hy9 148 16 steps step NNS cord-280571-ntgt5hy9 148 17 , , , cord-280571-ntgt5hy9 148 18 technical technical JJ cord-280571-ntgt5hy9 148 19 handson handson JJ cord-280571-ntgt5hy9 148 20 time time NN cord-280571-ntgt5hy9 148 21 , , , cord-280571-ntgt5hy9 148 22 and and CC cord-280571-ntgt5hy9 148 23 a a DT cord-280571-ntgt5hy9 148 24 potential potential NN cord-280571-ntgt5hy9 148 25 for for IN cord-280571-ntgt5hy9 148 26 amplicon amplicon NN cord-280571-ntgt5hy9 148 27 contamination contamination NN cord-280571-ntgt5hy9 148 28 . . . cord-280571-ntgt5hy9 149 1 There there EX cord-280571-ntgt5hy9 149 2 is be VBZ cord-280571-ntgt5hy9 149 3 a a DT cord-280571-ntgt5hy9 149 4 second second JJ cord-280571-ntgt5hy9 149 5 - - HYPH cord-280571-ntgt5hy9 149 6 generation generation NN cord-280571-ntgt5hy9 149 7 assay assay NN cord-280571-ntgt5hy9 149 8 called call VBN cord-280571-ntgt5hy9 149 9 RVP RVP NNP cord-280571-ntgt5hy9 149 10 FAST FAST NNP cord-280571-ntgt5hy9 149 11 ( ( -LRB- cord-280571-ntgt5hy9 149 12 Luminex Luminex NNP cord-280571-ntgt5hy9 149 13 ) ) -RRB- cord-280571-ntgt5hy9 149 14 available available JJ cord-280571-ntgt5hy9 149 15 in in IN cord-280571-ntgt5hy9 149 16 Europe Europe NNP cord-280571-ntgt5hy9 149 17 that that WDT cord-280571-ntgt5hy9 149 18 addresses address VBZ cord-280571-ntgt5hy9 149 19 several several JJ cord-280571-ntgt5hy9 149 20 of of IN cord-280571-ntgt5hy9 149 21 these these DT cord-280571-ntgt5hy9 149 22 issues issue NNS cord-280571-ntgt5hy9 149 23 by by IN cord-280571-ntgt5hy9 149 24 reducing reduce VBG cord-280571-ntgt5hy9 149 25 the the DT cord-280571-ntgt5hy9 149 26 number number NN cord-280571-ntgt5hy9 149 27 of of IN cord-280571-ntgt5hy9 149 28 steps step NNS cord-280571-ntgt5hy9 149 29 and and CC cord-280571-ntgt5hy9 149 30 the the DT cord-280571-ntgt5hy9 149 31 time time NN cord-280571-ntgt5hy9 149 32 to to TO cord-280571-ntgt5hy9 149 33 results result NNS cord-280571-ntgt5hy9 149 34 by by IN cord-280571-ntgt5hy9 149 35 3 3 CD cord-280571-ntgt5hy9 149 36 - - SYM cord-280571-ntgt5hy9 149 37 4 4 CD cord-280571-ntgt5hy9 149 38 h h NN cord-280571-ntgt5hy9 149 39 , , , cord-280571-ntgt5hy9 149 40 making make VBG cord-280571-ntgt5hy9 149 41 it -PRON- PRP cord-280571-ntgt5hy9 149 42 possible possible JJ cord-280571-ntgt5hy9 149 43 to to TO cord-280571-ntgt5hy9 149 44 provide provide VB cord-280571-ntgt5hy9 149 45 comprehensive comprehensive JJ cord-280571-ntgt5hy9 149 46 results result NNS cord-280571-ntgt5hy9 149 47 within within IN cord-280571-ntgt5hy9 149 48 a a DT cord-280571-ntgt5hy9 149 49 single single JJ cord-280571-ntgt5hy9 149 50 shift shift NN cord-280571-ntgt5hy9 149 51 . . . cord-280571-ntgt5hy9 150 1 Gen Gen NNP cord-280571-ntgt5hy9 150 2 - - HYPH cord-280571-ntgt5hy9 150 3 Probe Probe NNP cord-280571-ntgt5hy9 151 1 /Prodesse /Prodesse : cord-280571-ntgt5hy9 151 2 ProFlu,1ProFlu ProFlu,1ProFlu NNP cord-280571-ntgt5hy9 151 3 - - HYPH cord-280571-ntgt5hy9 151 4 ST ST NNP cord-280571-ntgt5hy9 151 5 , , , cord-280571-ntgt5hy9 151 6 Pro Pro NNP cord-280571-ntgt5hy9 151 7 hMPV1 hMPV1 NNP cord-280571-ntgt5hy9 151 8 , , , cord-280571-ntgt5hy9 151 9 and and CC cord-280571-ntgt5hy9 151 10 ProParaflu1 ProParaflu1 NNP cord-280571-ntgt5hy9 151 11 Assays Assays NNP cord-280571-ntgt5hy9 151 12 ( ( -LRB- cord-280571-ntgt5hy9 151 13 Gen Gen NNP cord-280571-ntgt5hy9 151 14 - - HYPH cord-280571-ntgt5hy9 151 15 Probe Probe NNP cord-280571-ntgt5hy9 151 16 / / SYM cord-280571-ntgt5hy9 151 17 Prodesse Prodesse NNP cord-280571-ntgt5hy9 151 18 ) ) -RRB- cord-280571-ntgt5hy9 152 1 Currently currently RB cord-280571-ntgt5hy9 152 2 , , , cord-280571-ntgt5hy9 152 3 there there EX cord-280571-ntgt5hy9 152 4 are be VBP cord-280571-ntgt5hy9 152 5 3 3 CD cord-280571-ntgt5hy9 152 6 Gen Gen NNP cord-280571-ntgt5hy9 152 7 - - HYPH cord-280571-ntgt5hy9 152 8 Probe Probe NNP cord-280571-ntgt5hy9 152 9 / / SYM cord-280571-ntgt5hy9 152 10 Prodesse Prodesse NNP cord-280571-ntgt5hy9 152 11 FDA FDA NNP cord-280571-ntgt5hy9 152 12 - - HYPH cord-280571-ntgt5hy9 152 13 cleared clear VBN cord-280571-ntgt5hy9 152 14 multiplex multiplex JJ cord-280571-ntgt5hy9 152 15 real real JJ cord-280571-ntgt5hy9 152 16 - - HYPH cord-280571-ntgt5hy9 152 17 time time NN cord-280571-ntgt5hy9 152 18 RT rt NN cord-280571-ntgt5hy9 152 19 - - HYPH cord-280571-ntgt5hy9 152 20 PCR PCR NNP cord-280571-ntgt5hy9 152 21 assays assay NNS cord-280571-ntgt5hy9 152 22 for for IN cord-280571-ntgt5hy9 152 23 the the DT cord-280571-ntgt5hy9 152 24 qualitative qualitative JJ cord-280571-ntgt5hy9 152 25 detection detection NN cord-280571-ntgt5hy9 152 26 and and CC cord-280571-ntgt5hy9 152 27 discrimination discrimination NN cord-280571-ntgt5hy9 152 28 of of IN cord-280571-ntgt5hy9 152 29 respiratory respiratory JJ cord-280571-ntgt5hy9 152 30 viruses virus NNS cord-280571-ntgt5hy9 152 31 . . . cord-280571-ntgt5hy9 153 1 The the DT cord-280571-ntgt5hy9 153 2 ProFlu1 ProFlu1 NNP cord-280571-ntgt5hy9 153 3 assay assay NN cord-280571-ntgt5hy9 153 4 targets target VBZ cord-280571-ntgt5hy9 153 5 the the DT cord-280571-ntgt5hy9 153 6 matrix matrix NN cord-280571-ntgt5hy9 153 7 gene gene NN cord-280571-ntgt5hy9 153 8 for for IN cord-280571-ntgt5hy9 153 9 influenza influenza NN cord-280571-ntgt5hy9 153 10 A A NNP cord-280571-ntgt5hy9 153 11 , , , cord-280571-ntgt5hy9 153 12 nonstructural nonstructural JJ cord-280571-ntgt5hy9 153 13 genes gene NNS cord-280571-ntgt5hy9 153 14 NS-1 NS-1 NNP cord-280571-ntgt5hy9 153 15 and and CC cord-280571-ntgt5hy9 153 16 NS-2 NS-2 NNP cord-280571-ntgt5hy9 153 17 for for IN cord-280571-ntgt5hy9 153 18 influenza influenza NN cord-280571-ntgt5hy9 153 19 B b NN cord-280571-ntgt5hy9 153 20 , , , cord-280571-ntgt5hy9 153 21 and and CC cord-280571-ntgt5hy9 153 22 the the DT cord-280571-ntgt5hy9 153 23 polymerase polymerase NN cord-280571-ntgt5hy9 153 24 gene gene NN cord-280571-ntgt5hy9 153 25 for for IN cord-280571-ntgt5hy9 153 26 RSV RSV NNP cord-280571-ntgt5hy9 153 27 A A NNP cord-280571-ntgt5hy9 153 28 and and CC cord-280571-ntgt5hy9 153 29 RSV RSV NNP cord-280571-ntgt5hy9 154 1 B. B. NNP cord-280571-ntgt5hy9 154 2 The the DT cord-280571-ntgt5hy9 154 3 Pro pro JJ cord-280571-ntgt5hy9 154 4 hMPV1 hmpv1 NN cord-280571-ntgt5hy9 154 5 assay assay NN cord-280571-ntgt5hy9 154 6 targets target VBZ cord-280571-ntgt5hy9 154 7 highly highly RB cord-280571-ntgt5hy9 154 8 conserved conserved JJ cord-280571-ntgt5hy9 154 9 regions region NNS cord-280571-ntgt5hy9 154 10 of of IN cord-280571-ntgt5hy9 154 11 the the DT cord-280571-ntgt5hy9 154 12 nucleocapsid nucleocapsid NN cord-280571-ntgt5hy9 154 13 ( ( -LRB- cord-280571-ntgt5hy9 154 14 N N NNP cord-280571-ntgt5hy9 154 15 ) ) -RRB- cord-280571-ntgt5hy9 154 16 gene gene NN cord-280571-ntgt5hy9 154 17 for for IN cord-280571-ntgt5hy9 154 18 hMPV hmpv NN cord-280571-ntgt5hy9 154 19 and and CC cord-280571-ntgt5hy9 154 20 a a DT cord-280571-ntgt5hy9 154 21 transcript transcript NN cord-280571-ntgt5hy9 154 22 derived derive VBN cord-280571-ntgt5hy9 154 23 from from IN cord-280571-ntgt5hy9 154 24 Escherichia Escherichia NNP cord-280571-ntgt5hy9 154 25 coli coli VBZ cord-280571-ntgt5hy9 154 26 Bacteriophage Bacteriophage NNP cord-280571-ntgt5hy9 154 27 MS2 MS2 NNP cord-280571-ntgt5hy9 154 28 A A NNP cord-280571-ntgt5hy9 154 29 - - HYPH cord-280571-ntgt5hy9 154 30 protein protein NN cord-280571-ntgt5hy9 154 31 gene gene NN cord-280571-ntgt5hy9 154 32 ( ( -LRB- cord-280571-ntgt5hy9 154 33 Internal Internal NNP cord-280571-ntgt5hy9 154 34 Control Control NNP cord-280571-ntgt5hy9 154 35 ) ) -RRB- cord-280571-ntgt5hy9 154 36 . . . cord-280571-ntgt5hy9 155 1 The the DT cord-280571-ntgt5hy9 155 2 ProParaflu1 ProParaflu1 NNP cord-280571-ntgt5hy9 155 3 assay assay NN cord-280571-ntgt5hy9 155 4 targets target VBZ cord-280571-ntgt5hy9 155 5 conserved conserve VBN cord-280571-ntgt5hy9 155 6 regions region NNS cord-280571-ntgt5hy9 155 7 of of IN cord-280571-ntgt5hy9 155 8 the the DT cord-280571-ntgt5hy9 155 9 hemagglutinin hemagglutinin NN cord-280571-ntgt5hy9 155 10 - - HYPH cord-280571-ntgt5hy9 155 11 neuraminidase neuraminidase NN cord-280571-ntgt5hy9 155 12 gene gene NN cord-280571-ntgt5hy9 155 13 for for IN cord-280571-ntgt5hy9 155 14 PIV-1 PIV-1 NNP cord-280571-ntgt5hy9 155 15 , , , cord-280571-ntgt5hy9 155 16 PIV-2 PIV-2 NNP cord-280571-ntgt5hy9 155 17 , , , cord-280571-ntgt5hy9 155 18 and and CC cord-280571-ntgt5hy9 155 19 PIV-3 PIV-3 NNP cord-280571-ntgt5hy9 155 20 and and CC cord-280571-ntgt5hy9 155 21 a a DT cord-280571-ntgt5hy9 155 22 transcript transcript NN cord-280571-ntgt5hy9 155 23 derived derive VBN cord-280571-ntgt5hy9 155 24 from from IN cord-280571-ntgt5hy9 155 25 E. E. NNP cord-280571-ntgt5hy9 155 26 coli coli VBZ cord-280571-ntgt5hy9 155 27 Bacteriophage Bacteriophage NNP cord-280571-ntgt5hy9 155 28 MS2 MS2 NNP cord-280571-ntgt5hy9 155 29 A A NNP cord-280571-ntgt5hy9 155 30 - - HYPH cord-280571-ntgt5hy9 155 31 protein protein NN cord-280571-ntgt5hy9 155 32 gene gene NN cord-280571-ntgt5hy9 155 33 ( ( -LRB- cord-280571-ntgt5hy9 155 34 Internal Internal NNP cord-280571-ntgt5hy9 155 35 Control Control NNP cord-280571-ntgt5hy9 155 36 ) ) -RRB- cord-280571-ntgt5hy9 155 37 . . . cord-280571-ntgt5hy9 156 1 All all DT cord-280571-ntgt5hy9 156 2 3 3 CD cord-280571-ntgt5hy9 156 3 assays assay NNS cord-280571-ntgt5hy9 156 4 are be VBP cord-280571-ntgt5hy9 156 5 approved approve VBN cord-280571-ntgt5hy9 156 6 for for IN cord-280571-ntgt5hy9 156 7 testing test VBG cord-280571-ntgt5hy9 156 8 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 156 9 swab swab NN cord-280571-ntgt5hy9 156 10 specimens specimen NNS cord-280571-ntgt5hy9 156 11 obtained obtain VBN cord-280571-ntgt5hy9 156 12 from from IN cord-280571-ntgt5hy9 156 13 symptomatic symptomatic JJ cord-280571-ntgt5hy9 156 14 persons person NNS cord-280571-ntgt5hy9 156 15 . . . cord-280571-ntgt5hy9 157 1 Viral viral JJ cord-280571-ntgt5hy9 157 2 nucleic nucleic JJ cord-280571-ntgt5hy9 157 3 acids acid NNS cord-280571-ntgt5hy9 157 4 from from IN cord-280571-ntgt5hy9 157 5 patient patient JJ cord-280571-ntgt5hy9 157 6 samples sample NNS cord-280571-ntgt5hy9 157 7 are be VBP cord-280571-ntgt5hy9 157 8 coextracted coextracte VBN cord-280571-ntgt5hy9 157 9 with with IN cord-280571-ntgt5hy9 157 10 an an DT cord-280571-ntgt5hy9 157 11 internal internal JJ cord-280571-ntgt5hy9 157 12 control control NN cord-280571-ntgt5hy9 157 13 that that WDT cord-280571-ntgt5hy9 157 14 monitors monitor VBZ cord-280571-ntgt5hy9 157 15 assay assay NN cord-280571-ntgt5hy9 157 16 performance performance NN cord-280571-ntgt5hy9 157 17 and and CC cord-280571-ntgt5hy9 157 18 the the DT cord-280571-ntgt5hy9 157 19 presence presence NN cord-280571-ntgt5hy9 157 20 of of IN cord-280571-ntgt5hy9 157 21 amplification amplification NN cord-280571-ntgt5hy9 157 22 inhibitors inhibitor NNS cord-280571-ntgt5hy9 157 23 that that WDT cord-280571-ntgt5hy9 157 24 could could MD cord-280571-ntgt5hy9 157 25 lead lead VB cord-280571-ntgt5hy9 157 26 to to IN cord-280571-ntgt5hy9 157 27 false false JJ cord-280571-ntgt5hy9 157 28 - - HYPH cord-280571-ntgt5hy9 157 29 negative negative JJ cord-280571-ntgt5hy9 157 30 results result NNS cord-280571-ntgt5hy9 157 31 . . . cord-280571-ntgt5hy9 158 1 Nucleic nucleic JJ cord-280571-ntgt5hy9 158 2 acids acid NNS cord-280571-ntgt5hy9 158 3 are be VBP cord-280571-ntgt5hy9 158 4 extracted extract VBN cord-280571-ntgt5hy9 158 5 using use VBG cord-280571-ntgt5hy9 158 6 a a DT cord-280571-ntgt5hy9 158 7 MagNA MagNA NNP cord-280571-ntgt5hy9 158 8 Pure Pure NNP cord-280571-ntgt5hy9 158 9 LC LC NNP cord-280571-ntgt5hy9 158 10 Instrument instrument NN cord-280571-ntgt5hy9 158 11 ( ( -LRB- cord-280571-ntgt5hy9 158 12 Roche Roche NNP cord-280571-ntgt5hy9 158 13 Diagnostics Diagnostics NNP cord-280571-ntgt5hy9 158 14 Corp Corp NNP cord-280571-ntgt5hy9 158 15 ) ) -RRB- cord-280571-ntgt5hy9 158 16 and and CC cord-280571-ntgt5hy9 158 17 the the DT cord-280571-ntgt5hy9 158 18 MagNA MagNA NNP cord-280571-ntgt5hy9 158 19 Pure Pure NNP cord-280571-ntgt5hy9 158 20 Total Total NNP cord-280571-ntgt5hy9 158 21 Nucleic Nucleic NNP cord-280571-ntgt5hy9 158 22 Acid acid NN cord-280571-ntgt5hy9 158 23 Isolation isolation NN cord-280571-ntgt5hy9 158 24 Kit kit NN cord-280571-ntgt5hy9 158 25 ( ( -LRB- cord-280571-ntgt5hy9 158 26 Roche Roche NNP cord-280571-ntgt5hy9 158 27 ) ) -RRB- cord-280571-ntgt5hy9 158 28 or or CC cord-280571-ntgt5hy9 158 29 a a DT cord-280571-ntgt5hy9 158 30 NucliSENS NucliSENS NNP cord-280571-ntgt5hy9 158 31 easyMAG easymag XX cord-280571-ntgt5hy9 158 32 System system NN cord-280571-ntgt5hy9 158 33 and and CC cord-280571-ntgt5hy9 158 34 the the DT cord-280571-ntgt5hy9 158 35 Automated Automated NNP cord-280571-ntgt5hy9 158 36 Magnetic Magnetic NNP cord-280571-ntgt5hy9 158 37 Extraction Extraction NNP cord-280571-ntgt5hy9 158 38 Reagents Reagents NNPS cord-280571-ntgt5hy9 158 39 ( ( -LRB- cord-280571-ntgt5hy9 158 40 bio bio NNP cord-280571-ntgt5hy9 158 41 - - HYPH cord-280571-ntgt5hy9 158 42 Mérieux Mérieux NNP cord-280571-ntgt5hy9 158 43 ) ) -RRB- cord-280571-ntgt5hy9 158 44 . . . cord-280571-ntgt5hy9 159 1 The the DT cord-280571-ntgt5hy9 159 2 purified purify VBN cord-280571-ntgt5hy9 159 3 nucleic nucleic JJ cord-280571-ntgt5hy9 159 4 acids acid NNS cord-280571-ntgt5hy9 159 5 are be VBP cord-280571-ntgt5hy9 159 6 amplified amplify VBN cord-280571-ntgt5hy9 159 7 by by IN cord-280571-ntgt5hy9 159 8 means mean NNS cord-280571-ntgt5hy9 159 9 of of IN cord-280571-ntgt5hy9 159 10 RT RT NNP cord-280571-ntgt5hy9 159 11 - - HYPH cord-280571-ntgt5hy9 159 12 PCR PCR NNP cord-280571-ntgt5hy9 159 13 using use VBG cord-280571-ntgt5hy9 159 14 target target NN cord-280571-ntgt5hy9 159 15 - - HYPH cord-280571-ntgt5hy9 159 16 specific specific JJ cord-280571-ntgt5hy9 159 17 oligonucleotide oligonucleotide JJ cord-280571-ntgt5hy9 159 18 primers primer NNS cord-280571-ntgt5hy9 159 19 and and CC cord-280571-ntgt5hy9 159 20 Taqman Taqman NNP cord-280571-ntgt5hy9 159 21 probes probe NNS cord-280571-ntgt5hy9 159 22 complementary complementary JJ cord-280571-ntgt5hy9 159 23 to to IN cord-280571-ntgt5hy9 159 24 highly highly RB cord-280571-ntgt5hy9 159 25 conserved conserve VBN cord-280571-ntgt5hy9 159 26 regions region NNS cord-280571-ntgt5hy9 159 27 of of IN cord-280571-ntgt5hy9 159 28 the the DT cord-280571-ntgt5hy9 159 29 target target NN cord-280571-ntgt5hy9 159 30 gene gene NN cord-280571-ntgt5hy9 159 31 . . . cord-280571-ntgt5hy9 160 1 The the DT cord-280571-ntgt5hy9 160 2 Taqman Taqman NNP cord-280571-ntgt5hy9 160 3 probes probe NNS cord-280571-ntgt5hy9 160 4 are be VBP cord-280571-ntgt5hy9 160 5 labeled label VBN cord-280571-ntgt5hy9 160 6 with with IN cord-280571-ntgt5hy9 160 7 a a DT cord-280571-ntgt5hy9 160 8 quencher quencher NN cord-280571-ntgt5hy9 160 9 dye dye NN cord-280571-ntgt5hy9 160 10 attached attach VBN cord-280571-ntgt5hy9 160 11 to to IN cord-280571-ntgt5hy9 160 12 the the DT cord-280571-ntgt5hy9 160 13 3'-end 3'-end CD cord-280571-ntgt5hy9 160 14 and and CC cord-280571-ntgt5hy9 160 15 a a DT cord-280571-ntgt5hy9 160 16 reporter reporter NN cord-280571-ntgt5hy9 160 17 dye dye NN cord-280571-ntgt5hy9 160 18 at at IN cord-280571-ntgt5hy9 160 19 the the DT cord-280571-ntgt5hy9 160 20 5'-end 5'-end CD cord-280571-ntgt5hy9 160 21 . . . cord-280571-ntgt5hy9 161 1 When when WRB cord-280571-ntgt5hy9 161 2 amplified amplify VBN cord-280571-ntgt5hy9 161 3 target target NN cord-280571-ntgt5hy9 161 4 is be VBZ cord-280571-ntgt5hy9 161 5 present present JJ cord-280571-ntgt5hy9 161 6 , , , cord-280571-ntgt5hy9 161 7 the the DT cord-280571-ntgt5hy9 161 8 probes probe NNS cord-280571-ntgt5hy9 161 9 bind bind VBP cord-280571-ntgt5hy9 161 10 and and CC cord-280571-ntgt5hy9 161 11 the the DT cord-280571-ntgt5hy9 161 12 5'-3 5'-3 CD cord-280571-ntgt5hy9 161 13 ' ' '' cord-280571-ntgt5hy9 161 14 exonuclease exonuclease NN cord-280571-ntgt5hy9 161 15 activity activity NN cord-280571-ntgt5hy9 161 16 of of IN cord-280571-ntgt5hy9 161 17 Taq Taq NNP cord-280571-ntgt5hy9 161 18 polymerase polymerase NN cord-280571-ntgt5hy9 161 19 cleaves cleave VBZ cord-280571-ntgt5hy9 161 20 the the DT cord-280571-ntgt5hy9 161 21 probe probe NN cord-280571-ntgt5hy9 161 22 , , , cord-280571-ntgt5hy9 161 23 thus thus RB cord-280571-ntgt5hy9 161 24 separating separate VBG cord-280571-ntgt5hy9 161 25 the the DT cord-280571-ntgt5hy9 161 26 reporter reporter NN cord-280571-ntgt5hy9 161 27 dye dye NN cord-280571-ntgt5hy9 161 28 from from IN cord-280571-ntgt5hy9 161 29 the the DT cord-280571-ntgt5hy9 161 30 quencher quencher NN cord-280571-ntgt5hy9 161 31 . . . cord-280571-ntgt5hy9 162 1 Because because IN cord-280571-ntgt5hy9 162 2 the the DT cord-280571-ntgt5hy9 162 3 quencher quencher NN cord-280571-ntgt5hy9 162 4 and and CC cord-280571-ntgt5hy9 162 5 reporter reporter NN cord-280571-ntgt5hy9 162 6 dye dye NN cord-280571-ntgt5hy9 162 7 are be VBP cord-280571-ntgt5hy9 162 8 now now RB cord-280571-ntgt5hy9 162 9 physically physically RB cord-280571-ntgt5hy9 162 10 separated separate VBN cord-280571-ntgt5hy9 162 11 , , , cord-280571-ntgt5hy9 162 12 there there EX cord-280571-ntgt5hy9 162 13 is be VBZ cord-280571-ntgt5hy9 162 14 an an DT cord-280571-ntgt5hy9 162 15 increase increase NN cord-280571-ntgt5hy9 162 16 in in IN cord-280571-ntgt5hy9 162 17 fluorescent fluorescent JJ cord-280571-ntgt5hy9 162 18 signal signal NN cord-280571-ntgt5hy9 162 19 upon upon IN cord-280571-ntgt5hy9 162 20 excitation excitation NN cord-280571-ntgt5hy9 162 21 from from IN cord-280571-ntgt5hy9 162 22 a a DT cord-280571-ntgt5hy9 162 23 light light JJ cord-280571-ntgt5hy9 162 24 source source NN cord-280571-ntgt5hy9 162 25 . . . cord-280571-ntgt5hy9 163 1 The the DT cord-280571-ntgt5hy9 163 2 fluorescent fluorescent NN cord-280571-ntgt5hy9 163 3 signal signal NN cord-280571-ntgt5hy9 163 4 increases increase NNS cord-280571-ntgt5hy9 163 5 with with IN cord-280571-ntgt5hy9 163 6 each each DT cord-280571-ntgt5hy9 163 7 cycle cycle NN cord-280571-ntgt5hy9 163 8 as as IN cord-280571-ntgt5hy9 163 9 additional additional JJ cord-280571-ntgt5hy9 163 10 reporter reporter NN cord-280571-ntgt5hy9 163 11 dye dye NN cord-280571-ntgt5hy9 163 12 molecules molecule NNS cord-280571-ntgt5hy9 163 13 are be VBP cord-280571-ntgt5hy9 163 14 cleaved cleave VBN cord-280571-ntgt5hy9 163 15 from from IN cord-280571-ntgt5hy9 163 16 their -PRON- PRP$ cord-280571-ntgt5hy9 163 17 respective respective JJ cord-280571-ntgt5hy9 163 18 probes probe NNS cord-280571-ntgt5hy9 163 19 . . . cord-280571-ntgt5hy9 164 1 During during IN cord-280571-ntgt5hy9 164 2 each each DT cord-280571-ntgt5hy9 164 3 PCR PCR NNP cord-280571-ntgt5hy9 164 4 cycle cycle NN cord-280571-ntgt5hy9 164 5 , , , cord-280571-ntgt5hy9 164 6 the the DT cord-280571-ntgt5hy9 164 7 fluorescent fluorescent JJ cord-280571-ntgt5hy9 164 8 intensity intensity NN cord-280571-ntgt5hy9 164 9 is be VBZ cord-280571-ntgt5hy9 164 10 monitored monitor VBN cord-280571-ntgt5hy9 164 11 by by IN cord-280571-ntgt5hy9 164 12 the the DT cord-280571-ntgt5hy9 164 13 realtime realtime JJ cord-280571-ntgt5hy9 164 14 instrument instrument NN cord-280571-ntgt5hy9 164 15 , , , cord-280571-ntgt5hy9 164 16 the the DT cord-280571-ntgt5hy9 164 17 SmartCycler SmartCycler NNP cord-280571-ntgt5hy9 164 18 II II NNP cord-280571-ntgt5hy9 164 19 ( ( -LRB- cord-280571-ntgt5hy9 164 20 time time NN cord-280571-ntgt5hy9 164 21 to to IN cord-280571-ntgt5hy9 164 22 results result NNS cord-280571-ntgt5hy9 164 23 , , , cord-280571-ntgt5hy9 164 24 including include VBG cord-280571-ntgt5hy9 164 25 extraction extraction NN cord-280571-ntgt5hy9 164 26 , , , cord-280571-ntgt5hy9 164 27 is be VBZ cord-280571-ntgt5hy9 164 28 approximately approximately RB cord-280571-ntgt5hy9 164 29 3 3 CD cord-280571-ntgt5hy9 164 30 - - SYM cord-280571-ntgt5hy9 164 31 3.5 3.5 CD cord-280571-ntgt5hy9 164 32 hr hr NN cord-280571-ntgt5hy9 164 33 for for IN cord-280571-ntgt5hy9 164 34 each each DT cord-280571-ntgt5hy9 164 35 test test NN cord-280571-ntgt5hy9 164 36 run run NN cord-280571-ntgt5hy9 164 37 ) ) -RRB- cord-280571-ntgt5hy9 164 38 . . . cord-280571-ntgt5hy9 165 1 The the DT cord-280571-ntgt5hy9 165 2 performance performance NN cord-280571-ntgt5hy9 165 3 characteristics characteristic NNS cord-280571-ntgt5hy9 165 4 of of IN cord-280571-ntgt5hy9 165 5 the the DT cord-280571-ntgt5hy9 165 6 assays assay NNS cord-280571-ntgt5hy9 165 7 were be VBD cord-280571-ntgt5hy9 165 8 established establish VBN cord-280571-ntgt5hy9 165 9 by by IN cord-280571-ntgt5hy9 165 10 the the DT cord-280571-ntgt5hy9 165 11 manufacturer manufacturer NN cord-280571-ntgt5hy9 165 12 through through IN cord-280571-ntgt5hy9 165 13 prospective prospective JJ cord-280571-ntgt5hy9 165 14 and and CC cord-280571-ntgt5hy9 165 15 retrospective retrospective JJ cord-280571-ntgt5hy9 165 16 clinical clinical JJ cord-280571-ntgt5hy9 165 17 studies study NNS cord-280571-ntgt5hy9 165 18 used use VBN cord-280571-ntgt5hy9 165 19 for for IN cord-280571-ntgt5hy9 165 20 FDA FDA NNP cord-280571-ntgt5hy9 165 21 clearance clearance NN cord-280571-ntgt5hy9 165 22 of of IN cord-280571-ntgt5hy9 165 23 the the DT cord-280571-ntgt5hy9 165 24 tests test NNS cord-280571-ntgt5hy9 165 25 . . . cord-280571-ntgt5hy9 166 1 ProFlu1 proflu1 JJ cord-280571-ntgt5hy9 166 2 assay assay NN cord-280571-ntgt5hy9 166 3 results result NNS cord-280571-ntgt5hy9 166 4 obtained obtain VBN cord-280571-ntgt5hy9 166 5 by by IN cord-280571-ntgt5hy9 166 6 testing test VBG cord-280571-ntgt5hy9 166 7 891 891 CD cord-280571-ntgt5hy9 166 8 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 166 9 samples sample NNS cord-280571-ntgt5hy9 166 10 were be VBD cord-280571-ntgt5hy9 166 11 compared compare VBN cord-280571-ntgt5hy9 166 12 with with IN cord-280571-ntgt5hy9 166 13 results result NNS cord-280571-ntgt5hy9 166 14 of of IN cord-280571-ntgt5hy9 166 15 rapid rapid JJ cord-280571-ntgt5hy9 166 16 shell shell NN cord-280571-ntgt5hy9 166 17 vial vial NN cord-280571-ntgt5hy9 166 18 culture culture NN cord-280571-ntgt5hy9 166 19 . . . cord-280571-ntgt5hy9 167 1 ProFlu1 ProFlu1 NNS cord-280571-ntgt5hy9 167 2 sensitivities sensitivity NNS cord-280571-ntgt5hy9 167 3 and and CC cord-280571-ntgt5hy9 167 4 specificities specificity NNS cord-280571-ntgt5hy9 167 5 for for IN cord-280571-ntgt5hy9 167 6 the the DT cord-280571-ntgt5hy9 167 7 detection detection NN cord-280571-ntgt5hy9 167 8 of of IN cord-280571-ntgt5hy9 167 9 influenza influenza NN cord-280571-ntgt5hy9 167 10 A a NN cord-280571-ntgt5hy9 167 11 were be VBD cord-280571-ntgt5hy9 167 12 100 100 CD cord-280571-ntgt5hy9 167 13 % % NN cord-280571-ntgt5hy9 167 14 and and CC cord-280571-ntgt5hy9 167 15 92.6 92.6 CD cord-280571-ntgt5hy9 167 16 % % NN cord-280571-ntgt5hy9 167 17 , , , cord-280571-ntgt5hy9 167 18 respectively respectively RB cord-280571-ntgt5hy9 167 19 ; ; : cord-280571-ntgt5hy9 167 20 for for IN cord-280571-ntgt5hy9 167 21 influenza influenza NN cord-280571-ntgt5hy9 167 22 B B NNP cord-280571-ntgt5hy9 167 23 were be VBD cord-280571-ntgt5hy9 167 24 97.8 97.8 CD cord-280571-ntgt5hy9 167 25 % % NN cord-280571-ntgt5hy9 167 26 and and CC cord-280571-ntgt5hy9 167 27 98.6 98.6 CD cord-280571-ntgt5hy9 167 28 % % NN cord-280571-ntgt5hy9 167 29 , , , cord-280571-ntgt5hy9 167 30 respectively respectively RB cord-280571-ntgt5hy9 167 31 ; ; : cord-280571-ntgt5hy9 167 32 and and CC cord-280571-ntgt5hy9 167 33 for for IN cord-280571-ntgt5hy9 167 34 RSV RSV NNP cord-280571-ntgt5hy9 167 35 were be VBD cord-280571-ntgt5hy9 167 36 89.5 89.5 CD cord-280571-ntgt5hy9 167 37 % % NN cord-280571-ntgt5hy9 167 38 and and CC cord-280571-ntgt5hy9 167 39 94.9 94.9 CD cord-280571-ntgt5hy9 167 40 % % NN cord-280571-ntgt5hy9 167 41 , , , cord-280571-ntgt5hy9 167 42 respectively respectively RB cord-280571-ntgt5hy9 167 43 [ [ -LRB- cord-280571-ntgt5hy9 167 44 102 102 CD cord-280571-ntgt5hy9 167 45 ] ] -RRB- cord-280571-ntgt5hy9 167 46 . . . cord-280571-ntgt5hy9 168 1 A a DT cord-280571-ntgt5hy9 168 2 study study NN cord-280571-ntgt5hy9 168 3 by by IN cord-280571-ntgt5hy9 168 4 Liao Liao NNP cord-280571-ntgt5hy9 168 5 et et NNP cord-280571-ntgt5hy9 168 6 al al NNP cord-280571-ntgt5hy9 168 7 compared compare VBD cord-280571-ntgt5hy9 168 8 the the DT cord-280571-ntgt5hy9 168 9 Prodesse Prodesse NNP cord-280571-ntgt5hy9 168 10 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 168 11 assay assay NN cord-280571-ntgt5hy9 168 12 , , , cord-280571-ntgt5hy9 168 13 a a DT cord-280571-ntgt5hy9 168 14 previous previous JJ cord-280571-ntgt5hy9 168 15 version version NN cord-280571-ntgt5hy9 168 16 of of IN cord-280571-ntgt5hy9 168 17 the the DT cord-280571-ntgt5hy9 168 18 ProFlu1 ProFlu1 NNP cord-280571-ntgt5hy9 168 19 assay assay NN cord-280571-ntgt5hy9 168 20 , , , cord-280571-ntgt5hy9 168 21 with with IN cord-280571-ntgt5hy9 168 22 viral viral JJ cord-280571-ntgt5hy9 168 23 culture culture NN cord-280571-ntgt5hy9 168 24 and and CC cord-280571-ntgt5hy9 168 25 RADTs radt NNS cord-280571-ntgt5hy9 168 26 for for IN cord-280571-ntgt5hy9 168 27 RSV RSV NNP cord-280571-ntgt5hy9 168 28 ( ( -LRB- cord-280571-ntgt5hy9 168 29 NOW now RB cord-280571-ntgt5hy9 168 30 RSV RSV NNP cord-280571-ntgt5hy9 168 31 , , , cord-280571-ntgt5hy9 168 32 Binax Binax NNP cord-280571-ntgt5hy9 168 33 , , , cord-280571-ntgt5hy9 168 34 Inverness Inverness NNP cord-280571-ntgt5hy9 168 35 Medical Medical NNP cord-280571-ntgt5hy9 168 36 ) ) -RRB- cord-280571-ntgt5hy9 168 37 and and CC cord-280571-ntgt5hy9 168 38 for for IN cord-280571-ntgt5hy9 168 39 influenza influenza NN cord-280571-ntgt5hy9 168 40 A a NN cord-280571-ntgt5hy9 168 41 and and CC cord-280571-ntgt5hy9 168 42 B B NNP cord-280571-ntgt5hy9 168 43 ( ( -LRB- cord-280571-ntgt5hy9 168 44 Directogen Directogen NNP cord-280571-ntgt5hy9 168 45 A1B a1b NN cord-280571-ntgt5hy9 168 46 , , , cord-280571-ntgt5hy9 168 47 BD BD NNP cord-280571-ntgt5hy9 168 48 Diagnostics Diagnostics NNP cord-280571-ntgt5hy9 168 49 ) ) -RRB- cord-280571-ntgt5hy9 168 50 [ [ -LRB- cord-280571-ntgt5hy9 168 51 10 10 CD cord-280571-ntgt5hy9 168 52 ] ] -RRB- cord-280571-ntgt5hy9 168 53 . . . cord-280571-ntgt5hy9 169 1 The the DT cord-280571-ntgt5hy9 169 2 specificities specificity NNS cord-280571-ntgt5hy9 169 3 of of IN cord-280571-ntgt5hy9 169 4 all all DT cord-280571-ntgt5hy9 169 5 methods method NNS cord-280571-ntgt5hy9 169 6 were be VBD cord-280571-ntgt5hy9 169 7 found find VBN cord-280571-ntgt5hy9 169 8 to to TO cord-280571-ntgt5hy9 169 9 be be VB cord-280571-ntgt5hy9 169 10 .99 .99 CD cord-280571-ntgt5hy9 169 11 % % NN cord-280571-ntgt5hy9 169 12 . . . cord-280571-ntgt5hy9 170 1 The the DT cord-280571-ntgt5hy9 170 2 sensitivities sensitivity NNS cord-280571-ntgt5hy9 170 3 for for IN cord-280571-ntgt5hy9 170 4 detection detection NN cord-280571-ntgt5hy9 170 5 of of IN cord-280571-ntgt5hy9 170 6 influenza influenza NN cord-280571-ntgt5hy9 170 7 were be VBD cord-280571-ntgt5hy9 170 8 59 59 CD cord-280571-ntgt5hy9 170 9 % % NN cord-280571-ntgt5hy9 170 10 for for IN cord-280571-ntgt5hy9 170 11 Directogen Directogen NNP cord-280571-ntgt5hy9 170 12 A A NNP cord-280571-ntgt5hy9 170 13 1 1 CD cord-280571-ntgt5hy9 170 14 B b NN cord-280571-ntgt5hy9 170 15 , , , cord-280571-ntgt5hy9 170 16 54 54 CD cord-280571-ntgt5hy9 170 17 % % NN cord-280571-ntgt5hy9 170 18 for for IN cord-280571-ntgt5hy9 170 19 viral viral JJ cord-280571-ntgt5hy9 170 20 culture culture NN cord-280571-ntgt5hy9 170 21 , , , cord-280571-ntgt5hy9 170 22 and and CC cord-280571-ntgt5hy9 170 23 98 98 CD cord-280571-ntgt5hy9 170 24 % % NN cord-280571-ntgt5hy9 170 25 for for IN cord-280571-ntgt5hy9 170 26 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 170 27 ; ; : cord-280571-ntgt5hy9 170 28 the the DT cord-280571-ntgt5hy9 170 29 sensitivities sensitivity NNS cord-280571-ntgt5hy9 170 30 for for IN cord-280571-ntgt5hy9 170 31 the the DT cord-280571-ntgt5hy9 170 32 detection detection NN cord-280571-ntgt5hy9 170 33 of of IN cord-280571-ntgt5hy9 170 34 RSV RSV NNP cord-280571-ntgt5hy9 170 35 were be VBD cord-280571-ntgt5hy9 170 36 82 82 CD cord-280571-ntgt5hy9 170 37 % % NN cord-280571-ntgt5hy9 170 38 for for IN cord-280571-ntgt5hy9 170 39 RSV RSV NNP cord-280571-ntgt5hy9 170 40 NOW now RB cord-280571-ntgt5hy9 170 41 , , , cord-280571-ntgt5hy9 170 42 57 57 CD cord-280571-ntgt5hy9 170 43 % % NN cord-280571-ntgt5hy9 170 44 for for IN cord-280571-ntgt5hy9 170 45 viral viral JJ cord-280571-ntgt5hy9 170 46 culture culture NN cord-280571-ntgt5hy9 170 47 , , , cord-280571-ntgt5hy9 170 48 and and CC cord-280571-ntgt5hy9 170 49 95 95 CD cord-280571-ntgt5hy9 170 50 % % NN cord-280571-ntgt5hy9 170 51 for for IN cord-280571-ntgt5hy9 170 52 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 170 53 . . . cord-280571-ntgt5hy9 171 1 In in IN cord-280571-ntgt5hy9 171 2 another another DT cord-280571-ntgt5hy9 171 3 study study NN cord-280571-ntgt5hy9 171 4 , , , cord-280571-ntgt5hy9 171 5 LeGoff LeGoff NNP cord-280571-ntgt5hy9 171 6 et et NNP cord-280571-ntgt5hy9 171 7 al al NNP cord-280571-ntgt5hy9 171 8 evaluated evaluate VBD cord-280571-ntgt5hy9 171 9 the the DT cord-280571-ntgt5hy9 171 10 performance performance NN cord-280571-ntgt5hy9 171 11 of of IN cord-280571-ntgt5hy9 171 12 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 171 13 in in IN cord-280571-ntgt5hy9 171 14 353 353 CD cord-280571-ntgt5hy9 171 15 pediatric pediatric JJ cord-280571-ntgt5hy9 171 16 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 171 17 specimens specimen NNS cord-280571-ntgt5hy9 171 18 [ [ -LRB- cord-280571-ntgt5hy9 171 19 40 40 CD cord-280571-ntgt5hy9 171 20 ] ] -RRB- cord-280571-ntgt5hy9 171 21 . . . cord-280571-ntgt5hy9 172 1 Results result NNS cord-280571-ntgt5hy9 172 2 were be VBD cord-280571-ntgt5hy9 172 3 compared compare VBN cord-280571-ntgt5hy9 172 4 with with IN cord-280571-ntgt5hy9 172 5 DFA DFA NNP cord-280571-ntgt5hy9 172 6 testing testing NN cord-280571-ntgt5hy9 172 7 and and CC cord-280571-ntgt5hy9 172 8 viral viral JJ cord-280571-ntgt5hy9 172 9 culture culture NN cord-280571-ntgt5hy9 172 10 . . . cord-280571-ntgt5hy9 173 1 The the DT cord-280571-ntgt5hy9 173 2 sensitivities sensitivity NNS cord-280571-ntgt5hy9 173 3 and and CC cord-280571-ntgt5hy9 173 4 specificities specificity NNS cord-280571-ntgt5hy9 173 5 of of IN cord-280571-ntgt5hy9 173 6 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 173 7 ranged range VBD cord-280571-ntgt5hy9 173 8 from from IN cord-280571-ntgt5hy9 173 9 97 97 CD cord-280571-ntgt5hy9 173 10 % % NN cord-280571-ntgt5hy9 173 11 to to TO cord-280571-ntgt5hy9 173 12 100 100 CD cord-280571-ntgt5hy9 173 13 % % NN cord-280571-ntgt5hy9 173 14 , , , cord-280571-ntgt5hy9 173 15 and and CC cord-280571-ntgt5hy9 173 16 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 173 17 detected detect VBD cord-280571-ntgt5hy9 173 18 viruses virus NNS cord-280571-ntgt5hy9 173 19 in in IN cord-280571-ntgt5hy9 173 20 9 9 CD cord-280571-ntgt5hy9 173 21 % % NN cord-280571-ntgt5hy9 173 22 of of IN cord-280571-ntgt5hy9 173 23 the the DT cord-280571-ntgt5hy9 173 24 samples sample NNS cord-280571-ntgt5hy9 173 25 that that WDT cord-280571-ntgt5hy9 173 26 had have VBD cord-280571-ntgt5hy9 173 27 negative negative JJ cord-280571-ntgt5hy9 173 28 results result NNS cord-280571-ntgt5hy9 173 29 by by IN cord-280571-ntgt5hy9 173 30 conventional conventional JJ cord-280571-ntgt5hy9 173 31 methods method NNS cord-280571-ntgt5hy9 173 32 . . . cord-280571-ntgt5hy9 174 1 In in IN cord-280571-ntgt5hy9 174 2 response response NN cord-280571-ntgt5hy9 174 3 to to IN cord-280571-ntgt5hy9 174 4 the the DT cord-280571-ntgt5hy9 174 5 2009 2009 CD cord-280571-ntgt5hy9 174 6 influenza influenza NN cord-280571-ntgt5hy9 174 7 A a DT cord-280571-ntgt5hy9 174 8 H1N1 H1N1 NNP cord-280571-ntgt5hy9 174 9 outbreak outbreak NN cord-280571-ntgt5hy9 174 10 , , , cord-280571-ntgt5hy9 174 11 an an DT cord-280571-ntgt5hy9 174 12 influenza influenza NN cord-280571-ntgt5hy9 174 13 A a DT cord-280571-ntgt5hy9 174 14 subtyping subtyping NN cord-280571-ntgt5hy9 174 15 assay assay NN cord-280571-ntgt5hy9 174 16 ( ( -LRB- cord-280571-ntgt5hy9 174 17 ProFlu ProFlu NNP cord-280571-ntgt5hy9 174 18 - - HYPH cord-280571-ntgt5hy9 174 19 ST ST NNP cord-280571-ntgt5hy9 174 20 ) ) -RRB- cord-280571-ntgt5hy9 174 21 was be VBD cord-280571-ntgt5hy9 174 22 developed develop VBN cord-280571-ntgt5hy9 174 23 by by IN cord-280571-ntgt5hy9 174 24 Prodesse Prodesse NNP cord-280571-ntgt5hy9 174 25 and and CC cord-280571-ntgt5hy9 174 26 received receive VBD cord-280571-ntgt5hy9 174 27 Emergency Emergency NNP cord-280571-ntgt5hy9 174 28 Use Use NNP cord-280571-ntgt5hy9 174 29 Authorization Authorization NNP cord-280571-ntgt5hy9 174 30 ( ( -LRB- cord-280571-ntgt5hy9 174 31 EUA EUA NNP cord-280571-ntgt5hy9 174 32 ) ) -RRB- cord-280571-ntgt5hy9 174 33 from from IN cord-280571-ntgt5hy9 174 34 the the DT cord-280571-ntgt5hy9 174 35 FDA FDA NNP cord-280571-ntgt5hy9 174 36 in in IN cord-280571-ntgt5hy9 174 37 July July NNP cord-280571-ntgt5hy9 174 38 2009 2009 CD cord-280571-ntgt5hy9 174 39 ( ( -LRB- cord-280571-ntgt5hy9 174 40 see see VB cord-280571-ntgt5hy9 174 41 EUA EUA NNP cord-280571-ntgt5hy9 174 42 section section NN cord-280571-ntgt5hy9 174 43 ) ) -RRB- cord-280571-ntgt5hy9 174 44 . . . cord-280571-ntgt5hy9 175 1 ProFlu ProFlu NNP cord-280571-ntgt5hy9 175 2 - - HYPH cord-280571-ntgt5hy9 175 3 ST ST NNP cord-280571-ntgt5hy9 175 4 is be VBZ cord-280571-ntgt5hy9 175 5 a a DT cord-280571-ntgt5hy9 175 6 qualitative qualitative JJ cord-280571-ntgt5hy9 175 7 multiplex multiplex JJ cord-280571-ntgt5hy9 175 8 real real JJ cord-280571-ntgt5hy9 175 9 - - HYPH cord-280571-ntgt5hy9 175 10 time time NN cord-280571-ntgt5hy9 175 11 RT RT NNP cord-280571-ntgt5hy9 175 12 - - HYPH cord-280571-ntgt5hy9 175 13 PCR PCR NNP cord-280571-ntgt5hy9 175 14 assay assay NN cord-280571-ntgt5hy9 175 15 that that WDT cord-280571-ntgt5hy9 175 16 targets target VBZ cord-280571-ntgt5hy9 175 17 the the DT cord-280571-ntgt5hy9 175 18 nucleoprotein nucleoprotein NNP cord-280571-ntgt5hy9 175 19 gene gene NN cord-280571-ntgt5hy9 175 20 of of IN cord-280571-ntgt5hy9 175 21 2009 2009 CD cord-280571-ntgt5hy9 175 22 influenza influenza NN cord-280571-ntgt5hy9 175 23 A a DT cord-280571-ntgt5hy9 175 24 H1N1 H1N1 NNP cord-280571-ntgt5hy9 175 25 , , , cord-280571-ntgt5hy9 175 26 the the DT cord-280571-ntgt5hy9 175 27 specific specific JJ cord-280571-ntgt5hy9 175 28 hemagglutinin hemagglutinin NN cord-280571-ntgt5hy9 175 29 genes gene NNS cord-280571-ntgt5hy9 175 30 of of IN cord-280571-ntgt5hy9 175 31 seasonal seasonal JJ cord-280571-ntgt5hy9 175 32 influenza influenza NN cord-280571-ntgt5hy9 175 33 A A NNP cord-280571-ntgt5hy9 175 34 / / SYM cord-280571-ntgt5hy9 175 35 H1 h1 NN cord-280571-ntgt5hy9 175 36 and and CC cord-280571-ntgt5hy9 175 37 seasonal seasonal JJ cord-280571-ntgt5hy9 175 38 influenza influenza NN cord-280571-ntgt5hy9 175 39 A A NNP cord-280571-ntgt5hy9 175 40 / / SYM cord-280571-ntgt5hy9 175 41 H3 H3 NNP cord-280571-ntgt5hy9 175 42 , , , cord-280571-ntgt5hy9 175 43 and and CC cord-280571-ntgt5hy9 175 44 an an DT cord-280571-ntgt5hy9 175 45 internal internal JJ cord-280571-ntgt5hy9 175 46 control control NN cord-280571-ntgt5hy9 175 47 ( ( -LRB- cord-280571-ntgt5hy9 175 48 MS2 MS2 NNP cord-280571-ntgt5hy9 175 49 phage phage NN cord-280571-ntgt5hy9 175 50 ) ) -RRB- cord-280571-ntgt5hy9 175 51 . . . cord-280571-ntgt5hy9 176 1 The the DT cord-280571-ntgt5hy9 176 2 identification identification NN cord-280571-ntgt5hy9 176 3 of of IN cord-280571-ntgt5hy9 176 4 2009 2009 CD cord-280571-ntgt5hy9 176 5 influenza influenza NN cord-280571-ntgt5hy9 176 6 A a DT cord-280571-ntgt5hy9 176 7 H1N1 H1N1 NNP cord-280571-ntgt5hy9 176 8 is be VBZ cord-280571-ntgt5hy9 176 9 aided aid VBN cord-280571-ntgt5hy9 176 10 by by IN cord-280571-ntgt5hy9 176 11 an an DT cord-280571-ntgt5hy9 176 12 algorithm algorithm NN cord-280571-ntgt5hy9 176 13 that that WDT cord-280571-ntgt5hy9 176 14 relies rely VBZ cord-280571-ntgt5hy9 176 15 on on IN cord-280571-ntgt5hy9 176 16 seasonal seasonal JJ cord-280571-ntgt5hy9 176 17 influenza influenza NN cord-280571-ntgt5hy9 176 18 A A NNP cord-280571-ntgt5hy9 176 19 / / SYM cord-280571-ntgt5hy9 176 20 H1 H1 NNP cord-280571-ntgt5hy9 176 21 virus virus NN cord-280571-ntgt5hy9 176 22 and and CC cord-280571-ntgt5hy9 176 23 seasonal seasonal JJ cord-280571-ntgt5hy9 176 24 influenza influenza NN cord-280571-ntgt5hy9 176 25 A A NNP cord-280571-ntgt5hy9 176 26 / / SYM cord-280571-ntgt5hy9 176 27 H3 H3 NNP cord-280571-ntgt5hy9 176 28 virus virus NN cord-280571-ntgt5hy9 176 29 results result VBZ cord-280571-ntgt5hy9 176 30 in in IN cord-280571-ntgt5hy9 176 31 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 176 32 swab swab NN cord-280571-ntgt5hy9 176 33 specimens specimen NNS cord-280571-ntgt5hy9 176 34 from from IN cord-280571-ntgt5hy9 176 35 patients patient NNS cord-280571-ntgt5hy9 176 36 who who WP cord-280571-ntgt5hy9 176 37 receive receive VBP cord-280571-ntgt5hy9 176 38 a a DT cord-280571-ntgt5hy9 176 39 diagnosis diagnosis NN cord-280571-ntgt5hy9 176 40 of of IN cord-280571-ntgt5hy9 176 41 influenza influenza NN cord-280571-ntgt5hy9 176 42 A a NN cord-280571-ntgt5hy9 176 43 by by IN cord-280571-ntgt5hy9 176 44 a a DT cord-280571-ntgt5hy9 176 45 currently currently RB cord-280571-ntgt5hy9 176 46 available available JJ cord-280571-ntgt5hy9 176 47 FDA FDA NNP cord-280571-ntgt5hy9 176 48 - - HYPH cord-280571-ntgt5hy9 176 49 cleared clear VBN cord-280571-ntgt5hy9 176 50 or or CC cord-280571-ntgt5hy9 176 51 authorized authorize VBN cord-280571-ntgt5hy9 176 52 device device NN cord-280571-ntgt5hy9 176 53 . . . cord-280571-ntgt5hy9 177 1 This this DT cord-280571-ntgt5hy9 177 2 assay assay NN cord-280571-ntgt5hy9 177 3 is be VBZ cord-280571-ntgt5hy9 177 4 intended intend VBN cord-280571-ntgt5hy9 177 5 for for IN cord-280571-ntgt5hy9 177 6 use use NN cord-280571-ntgt5hy9 177 7 in in IN cord-280571-ntgt5hy9 177 8 only only JJ cord-280571-ntgt5hy9 177 9 CLIA CLIA NNP cord-280571-ntgt5hy9 177 10 high high JJ cord-280571-ntgt5hy9 177 11 - - HYPH cord-280571-ntgt5hy9 177 12 complexity complexity NN cord-280571-ntgt5hy9 177 13 laboratories laboratory NNS cord-280571-ntgt5hy9 177 14 . . . cord-280571-ntgt5hy9 178 1 The the DT cord-280571-ntgt5hy9 178 2 performance performance NN cord-280571-ntgt5hy9 178 3 of of IN cord-280571-ntgt5hy9 178 4 the the DT cord-280571-ntgt5hy9 178 5 assay assay NN cord-280571-ntgt5hy9 178 6 was be VBD cord-280571-ntgt5hy9 178 7 evaluated evaluate VBN cord-280571-ntgt5hy9 178 8 retrospectively retrospectively RB cord-280571-ntgt5hy9 178 9 using use VBG cord-280571-ntgt5hy9 178 10 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 178 11 swab swab NN cord-280571-ntgt5hy9 178 12 specimens specimen NNS cord-280571-ntgt5hy9 178 13 that that WDT cord-280571-ntgt5hy9 178 14 were be VBD cord-280571-ntgt5hy9 178 15 previously previously RB cord-280571-ntgt5hy9 178 16 tested test VBN cord-280571-ntgt5hy9 178 17 with with IN cord-280571-ntgt5hy9 178 18 either either CC cord-280571-ntgt5hy9 178 19 the the DT cord-280571-ntgt5hy9 178 20 CDC CDC NNP cord-280571-ntgt5hy9 178 21 rRT rRT NNP cord-280571-ntgt5hy9 178 22 - - HYPH cord-280571-ntgt5hy9 178 23 PCR PCR NNP cord-280571-ntgt5hy9 178 24 Flu Flu NNP cord-280571-ntgt5hy9 178 25 Panel Panel NNP cord-280571-ntgt5hy9 178 26 ( ( -LRB- cord-280571-ntgt5hy9 178 27 IVD IVD NNP cord-280571-ntgt5hy9 178 28 device device NN cord-280571-ntgt5hy9 178 29 ) ) -RRB- cord-280571-ntgt5hy9 178 30 to to TO cord-280571-ntgt5hy9 178 31 detect detect VB cord-280571-ntgt5hy9 178 32 seasonal seasonal JJ cord-280571-ntgt5hy9 178 33 influenza influenza NN cord-280571-ntgt5hy9 178 34 A A NNP cord-280571-ntgt5hy9 178 35 / / SYM cord-280571-ntgt5hy9 178 36 H1 h1 NN cord-280571-ntgt5hy9 178 37 and and CC cord-280571-ntgt5hy9 178 38 influenza influenza NN cord-280571-ntgt5hy9 178 39 A A NNP cord-280571-ntgt5hy9 178 40 / / SYM cord-280571-ntgt5hy9 178 41 H3 H3 NNP cord-280571-ntgt5hy9 178 42 or or CC cord-280571-ntgt5hy9 178 43 the the DT cord-280571-ntgt5hy9 178 44 CDC CDC NNP cord-280571-ntgt5hy9 178 45 rRT rRT NNP cord-280571-ntgt5hy9 178 46 - - HYPH cord-280571-ntgt5hy9 178 47 PCR PCR NNP cord-280571-ntgt5hy9 178 48 Swine Swine NNP cord-280571-ntgt5hy9 178 49 Flu Flu NNP cord-280571-ntgt5hy9 178 50 Panel Panel NNP cord-280571-ntgt5hy9 178 51 ( ( -LRB- cord-280571-ntgt5hy9 178 52 EUA EUA NNP cord-280571-ntgt5hy9 178 53 ) ) -RRB- cord-280571-ntgt5hy9 178 54 . . . cord-280571-ntgt5hy9 179 1 The the DT cord-280571-ntgt5hy9 179 2 positive positive JJ cord-280571-ntgt5hy9 179 3 and and CC cord-280571-ntgt5hy9 179 4 negative negative JJ cord-280571-ntgt5hy9 179 5 agreements agreement NNS cord-280571-ntgt5hy9 179 6 for for IN cord-280571-ntgt5hy9 179 7 the the DT cord-280571-ntgt5hy9 179 8 detection detection NN cord-280571-ntgt5hy9 179 9 of of IN cord-280571-ntgt5hy9 179 10 seasonal seasonal JJ cord-280571-ntgt5hy9 179 11 influenza influenza NN cord-280571-ntgt5hy9 179 12 A/ A/ NNP cord-280571-ntgt5hy9 180 1 H1were h1were RB cord-280571-ntgt5hy9 181 1 95.8 95.8 CD cord-280571-ntgt5hy9 181 2 % % NN cord-280571-ntgt5hy9 181 3 and and CC cord-280571-ntgt5hy9 181 4 100 100 CD cord-280571-ntgt5hy9 181 5 % % NN cord-280571-ntgt5hy9 181 6 , , , cord-280571-ntgt5hy9 181 7 respectively respectively RB cord-280571-ntgt5hy9 181 8 ; ; : cord-280571-ntgt5hy9 181 9 for for IN cord-280571-ntgt5hy9 181 10 seasonal seasonal JJ cord-280571-ntgt5hy9 181 11 influenza influenza NN cord-280571-ntgt5hy9 181 12 A A NNP cord-280571-ntgt5hy9 181 13 / / SYM cord-280571-ntgt5hy9 181 14 H3 H3 NNP cord-280571-ntgt5hy9 181 15 were be VBD cord-280571-ntgt5hy9 181 16 100 100 CD cord-280571-ntgt5hy9 181 17 % % NN cord-280571-ntgt5hy9 181 18 and and CC cord-280571-ntgt5hy9 181 19 100 100 CD cord-280571-ntgt5hy9 181 20 % % NN cord-280571-ntgt5hy9 181 21 , , , cord-280571-ntgt5hy9 181 22 respectively respectively RB cord-280571-ntgt5hy9 181 23 ; ; : cord-280571-ntgt5hy9 181 24 and and CC cord-280571-ntgt5hy9 181 25 for for IN cord-280571-ntgt5hy9 181 26 2009 2009 CD cord-280571-ntgt5hy9 181 27 influenza influenza NN cord-280571-ntgt5hy9 181 28 A a DT cord-280571-ntgt5hy9 181 29 H1N1 H1N1 NNP cord-280571-ntgt5hy9 181 30 were be VBD cord-280571-ntgt5hy9 181 31 96.2 96.2 CD cord-280571-ntgt5hy9 181 32 % % NN cord-280571-ntgt5hy9 181 33 and and CC cord-280571-ntgt5hy9 181 34 100 100 CD cord-280571-ntgt5hy9 181 35 % % NN cord-280571-ntgt5hy9 181 36 , , , cord-280571-ntgt5hy9 181 37 respectively respectively RB cord-280571-ntgt5hy9 181 38 [ [ -LRB- cord-280571-ntgt5hy9 181 39 103 103 CD cord-280571-ntgt5hy9 181 40 ] ] -RRB- cord-280571-ntgt5hy9 181 41 . . . cord-280571-ntgt5hy9 182 1 The the DT cord-280571-ntgt5hy9 182 2 Pro pro JJ cord-280571-ntgt5hy9 182 3 hMPV1 hmpv1 NN cord-280571-ntgt5hy9 182 4 assay assay NN cord-280571-ntgt5hy9 182 5 clinical clinical JJ cord-280571-ntgt5hy9 182 6 trial trial NN cord-280571-ntgt5hy9 182 7 study study NN cord-280571-ntgt5hy9 182 8 for for IN cord-280571-ntgt5hy9 182 9 FDA FDA NNP cord-280571-ntgt5hy9 182 10 clearance clearance NN cord-280571-ntgt5hy9 182 11 evaluated evaluate VBD cord-280571-ntgt5hy9 182 12 the the DT cord-280571-ntgt5hy9 182 13 assay assay NN cord-280571-ntgt5hy9 182 14 's 's POS cord-280571-ntgt5hy9 182 15 clinical clinical JJ cord-280571-ntgt5hy9 182 16 performance performance NN cord-280571-ntgt5hy9 182 17 using use VBG cord-280571-ntgt5hy9 182 18 1275 1275 CD cord-280571-ntgt5hy9 182 19 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 182 20 swab swab NN cord-280571-ntgt5hy9 182 21 specimens specimen NNS cord-280571-ntgt5hy9 182 22 tested test VBN cord-280571-ntgt5hy9 182 23 by by IN cord-280571-ntgt5hy9 182 24 4 4 CD cord-280571-ntgt5hy9 182 25 clinical clinical JJ cord-280571-ntgt5hy9 182 26 laboratories laboratory NNS cord-280571-ntgt5hy9 182 27 across across IN cord-280571-ntgt5hy9 182 28 the the DT cord-280571-ntgt5hy9 182 29 United United NNP cord-280571-ntgt5hy9 182 30 States States NNP cord-280571-ntgt5hy9 182 31 . . . cord-280571-ntgt5hy9 183 1 Using use VBG cord-280571-ntgt5hy9 183 2 the the DT cord-280571-ntgt5hy9 183 3 Luminex Luminex NNP cord-280571-ntgt5hy9 183 4 RVP RVP NNP cord-280571-ntgt5hy9 183 5 assay assay NN cord-280571-ntgt5hy9 183 6 as as IN cord-280571-ntgt5hy9 183 7 the the DT cord-280571-ntgt5hy9 183 8 predicate predicate NN cord-280571-ntgt5hy9 183 9 device device NN cord-280571-ntgt5hy9 183 10 , , , cord-280571-ntgt5hy9 183 11 the the DT cord-280571-ntgt5hy9 183 12 sensitivity sensitivity NN cord-280571-ntgt5hy9 183 13 of of IN cord-280571-ntgt5hy9 183 14 Pro Pro NNP cord-280571-ntgt5hy9 183 15 hMPV1 hmpv1 NN cord-280571-ntgt5hy9 183 16 was be VBD cord-280571-ntgt5hy9 183 17 94.1 94.1 CD cord-280571-ntgt5hy9 183 18 % % NN cord-280571-ntgt5hy9 183 19 and and CC cord-280571-ntgt5hy9 183 20 the the DT cord-280571-ntgt5hy9 183 21 specificity specificity NN cord-280571-ntgt5hy9 183 22 was be VBD cord-280571-ntgt5hy9 183 23 99.3 99.3 CD cord-280571-ntgt5hy9 183 24 % % NN cord-280571-ntgt5hy9 183 25 [ [ -LRB- cord-280571-ntgt5hy9 183 26 104 104 CD cord-280571-ntgt5hy9 183 27 ] ] -RRB- cord-280571-ntgt5hy9 183 28 . . . cord-280571-ntgt5hy9 184 1 The the DT cord-280571-ntgt5hy9 184 2 performance performance NN cord-280571-ntgt5hy9 184 3 of of IN cord-280571-ntgt5hy9 184 4 the the DT cord-280571-ntgt5hy9 184 5 ProParaflu1 ProParaflu1 NNP cord-280571-ntgt5hy9 184 6 assay assay NN cord-280571-ntgt5hy9 184 7 was be VBD cord-280571-ntgt5hy9 184 8 evaluated evaluate VBN cord-280571-ntgt5hy9 184 9 during during IN cord-280571-ntgt5hy9 184 10 the the DT cord-280571-ntgt5hy9 184 11 clinical clinical JJ cord-280571-ntgt5hy9 184 12 trials trial NNS cord-280571-ntgt5hy9 184 13 for for IN cord-280571-ntgt5hy9 184 14 FDA FDA NNP cord-280571-ntgt5hy9 184 15 clearance clearance NN cord-280571-ntgt5hy9 184 16 . . . cord-280571-ntgt5hy9 185 1 Using use VBG cord-280571-ntgt5hy9 185 2 857 857 CD cord-280571-ntgt5hy9 185 3 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 185 4 swab swab NN cord-280571-ntgt5hy9 185 5 specimens specimen NNS cord-280571-ntgt5hy9 185 6 tested test VBN cord-280571-ntgt5hy9 185 7 by by IN cord-280571-ntgt5hy9 185 8 4 4 CD cord-280571-ntgt5hy9 185 9 clinical clinical JJ cord-280571-ntgt5hy9 185 10 laboratories laboratory NNS cord-280571-ntgt5hy9 185 11 across across IN cord-280571-ntgt5hy9 185 12 the the DT cord-280571-ntgt5hy9 185 13 United United NNP cord-280571-ntgt5hy9 185 14 States States NNP cord-280571-ntgt5hy9 185 15 [ [ -LRB- cord-280571-ntgt5hy9 185 16 105 105 CD cord-280571-ntgt5hy9 185 17 ] ] -RRB- cord-280571-ntgt5hy9 185 18 , , , cord-280571-ntgt5hy9 185 19 the the DT cord-280571-ntgt5hy9 185 20 sensitivities sensitivity NNS cord-280571-ntgt5hy9 185 21 and and CC cord-280571-ntgt5hy9 185 22 specificities specificity NNS cord-280571-ntgt5hy9 185 23 of of IN cord-280571-ntgt5hy9 185 24 the the DT cord-280571-ntgt5hy9 185 25 assay assay NN cord-280571-ntgt5hy9 185 26 for for IN cord-280571-ntgt5hy9 185 27 the the DT cord-280571-ntgt5hy9 185 28 detection detection NN cord-280571-ntgt5hy9 185 29 of of IN cord-280571-ntgt5hy9 185 30 PIV-1 PIV-1 NNP cord-280571-ntgt5hy9 185 31 were be VBD cord-280571-ntgt5hy9 185 32 88.9 88.9 CD cord-280571-ntgt5hy9 185 33 % % NN cord-280571-ntgt5hy9 185 34 and and CC cord-280571-ntgt5hy9 185 35 99.9 99.9 CD cord-280571-ntgt5hy9 185 36 % % NN cord-280571-ntgt5hy9 185 37 , , , cord-280571-ntgt5hy9 185 38 respectively respectively RB cord-280571-ntgt5hy9 185 39 ; ; : cord-280571-ntgt5hy9 185 40 for for IN cord-280571-ntgt5hy9 185 41 the the DT cord-280571-ntgt5hy9 185 42 detection detection NN cord-280571-ntgt5hy9 185 43 of of IN cord-280571-ntgt5hy9 185 44 PIV-2 PIV-2 NNP cord-280571-ntgt5hy9 185 45 were be VBD cord-280571-ntgt5hy9 185 46 96.3 96.3 CD cord-280571-ntgt5hy9 185 47 % % NN cord-280571-ntgt5hy9 185 48 and and CC cord-280571-ntgt5hy9 185 49 99.8 99.8 CD cord-280571-ntgt5hy9 185 50 % % NN cord-280571-ntgt5hy9 185 51 , , , cord-280571-ntgt5hy9 185 52 respectively respectively RB cord-280571-ntgt5hy9 185 53 , , , cord-280571-ntgt5hy9 185 54 and and CC cord-280571-ntgt5hy9 185 55 for for IN cord-280571-ntgt5hy9 185 56 the the DT cord-280571-ntgt5hy9 185 57 detection detection NN cord-280571-ntgt5hy9 185 58 of of IN cord-280571-ntgt5hy9 185 59 PIV-3 PIV-3 NNP cord-280571-ntgt5hy9 185 60 were be VBD cord-280571-ntgt5hy9 185 61 97.3 97.3 CD cord-280571-ntgt5hy9 185 62 % % NN cord-280571-ntgt5hy9 185 63 and and CC cord-280571-ntgt5hy9 185 64 99.2 99.2 CD cord-280571-ntgt5hy9 185 65 % % NN cord-280571-ntgt5hy9 185 66 , , , cord-280571-ntgt5hy9 185 67 respectively respectively RB cord-280571-ntgt5hy9 185 68 [ [ -LRB- cord-280571-ntgt5hy9 185 69 105 105 CD cord-280571-ntgt5hy9 185 70 ] ] -RRB- cord-280571-ntgt5hy9 185 71 . . . cord-280571-ntgt5hy9 186 1 At at IN cord-280571-ntgt5hy9 186 2 this this DT cord-280571-ntgt5hy9 186 3 time time NN cord-280571-ntgt5hy9 186 4 , , , cord-280571-ntgt5hy9 186 5 no no DT cord-280571-ntgt5hy9 186 6 additional additional JJ cord-280571-ntgt5hy9 186 7 independent independent JJ cord-280571-ntgt5hy9 186 8 performance performance NN cord-280571-ntgt5hy9 186 9 data datum NNS cord-280571-ntgt5hy9 186 10 are be VBP cord-280571-ntgt5hy9 186 11 available available JJ cord-280571-ntgt5hy9 186 12 . . . cord-280571-ntgt5hy9 187 1 The the DT cord-280571-ntgt5hy9 187 2 benefits benefit NNS cord-280571-ntgt5hy9 187 3 of of IN cord-280571-ntgt5hy9 187 4 the the DT cord-280571-ntgt5hy9 187 5 Gen Gen NNP cord-280571-ntgt5hy9 187 6 - - HYPH cord-280571-ntgt5hy9 187 7 Probe Probe NNP cord-280571-ntgt5hy9 187 8 / / SYM cord-280571-ntgt5hy9 187 9 Prodesse Prodesse NNP cord-280571-ntgt5hy9 187 10 assays assay NNS cord-280571-ntgt5hy9 187 11 include include VBP cord-280571-ntgt5hy9 187 12 ease ease NN cord-280571-ntgt5hy9 187 13 of of IN cord-280571-ntgt5hy9 187 14 use use NN cord-280571-ntgt5hy9 187 15 , , , cord-280571-ntgt5hy9 187 16 with with IN cord-280571-ntgt5hy9 187 17 approximately approximately RB cord-280571-ntgt5hy9 187 18 1.5 1.5 CD cord-280571-ntgt5hy9 187 19 h h NN cord-280571-ntgt5hy9 187 20 of of IN cord-280571-ntgt5hy9 187 21 hands hand NNS cord-280571-ntgt5hy9 187 22 - - HYPH cord-280571-ntgt5hy9 187 23 on on RP cord-280571-ntgt5hy9 187 24 time time NN cord-280571-ntgt5hy9 187 25 for for IN cord-280571-ntgt5hy9 187 26 nucleic nucleic JJ cord-280571-ntgt5hy9 187 27 acid acid NN cord-280571-ntgt5hy9 187 28 extraction extraction NN cord-280571-ntgt5hy9 187 29 preparation preparation NN cord-280571-ntgt5hy9 187 30 and and CC cord-280571-ntgt5hy9 187 31 a a DT cord-280571-ntgt5hy9 187 32 1-step 1-step CD cord-280571-ntgt5hy9 187 33 RT RT NNP cord-280571-ntgt5hy9 187 34 - - HYPH cord-280571-ntgt5hy9 187 35 PCR PCR NNP cord-280571-ntgt5hy9 187 36 setup setup NN cord-280571-ntgt5hy9 187 37 . . . cord-280571-ntgt5hy9 188 1 The the DT cord-280571-ntgt5hy9 188 2 overall overall JJ cord-280571-ntgt5hy9 188 3 time time NN cord-280571-ntgt5hy9 188 4 to to IN cord-280571-ntgt5hy9 188 5 results result NNS cord-280571-ntgt5hy9 188 6 is be VBZ cord-280571-ntgt5hy9 188 7 4.5 4.5 CD cord-280571-ntgt5hy9 188 8 - - SYM cord-280571-ntgt5hy9 188 9 5.5 5.5 CD cord-280571-ntgt5hy9 188 10 h. h. NN cord-280571-ntgt5hy9 188 11 Multiple multiple JJ cord-280571-ntgt5hy9 188 12 SmartCycler SmartCycler NNP cord-280571-ntgt5hy9 188 13 instruments instrument NNS cord-280571-ntgt5hy9 188 14 can can MD cord-280571-ntgt5hy9 188 15 be be VB cord-280571-ntgt5hy9 188 16 run run VBN cord-280571-ntgt5hy9 188 17 simultaneously simultaneously RB cord-280571-ntgt5hy9 188 18 , , , cord-280571-ntgt5hy9 188 19 with with IN cord-280571-ntgt5hy9 188 20 as as RB cord-280571-ntgt5hy9 188 21 many many JJ cord-280571-ntgt5hy9 188 22 units unit NNS cord-280571-ntgt5hy9 188 23 per per IN cord-280571-ntgt5hy9 188 24 cycler cycler NN cord-280571-ntgt5hy9 188 25 used use VBN cord-280571-ntgt5hy9 188 26 as as IN cord-280571-ntgt5hy9 188 27 needed need VBN cord-280571-ntgt5hy9 188 28 , , , cord-280571-ntgt5hy9 188 29 giving give VBG cord-280571-ntgt5hy9 188 30 flexibility flexibility NN cord-280571-ntgt5hy9 188 31 to to TO cord-280571-ntgt5hy9 188 32 run run VB cord-280571-ntgt5hy9 188 33 sizes size NNS cord-280571-ntgt5hy9 188 34 . . . cord-280571-ntgt5hy9 189 1 Because because IN cord-280571-ntgt5hy9 189 2 tubes tube NNS cord-280571-ntgt5hy9 189 3 containing contain VBG cord-280571-ntgt5hy9 189 4 amplicons amplicon NNS cord-280571-ntgt5hy9 189 5 are be VBP cord-280571-ntgt5hy9 189 6 never never RB cord-280571-ntgt5hy9 189 7 opened open VBN cord-280571-ntgt5hy9 189 8 , , , cord-280571-ntgt5hy9 189 9 the the DT cord-280571-ntgt5hy9 189 10 risk risk NN cord-280571-ntgt5hy9 189 11 of of IN cord-280571-ntgt5hy9 189 12 amplicon amplicon NN cord-280571-ntgt5hy9 189 13 contamination contamination NN cord-280571-ntgt5hy9 189 14 is be VBZ cord-280571-ntgt5hy9 189 15 minimal minimal JJ cord-280571-ntgt5hy9 189 16 . . . cord-280571-ntgt5hy9 190 1 One one CD cord-280571-ntgt5hy9 190 2 limitation limitation NN cord-280571-ntgt5hy9 190 3 of of IN cord-280571-ntgt5hy9 190 4 the the DT cord-280571-ntgt5hy9 190 5 assays assay NNS cord-280571-ntgt5hy9 190 6 is be VBZ cord-280571-ntgt5hy9 190 7 a a DT cord-280571-ntgt5hy9 190 8 maximum maximum NN cord-280571-ntgt5hy9 190 9 of of IN cord-280571-ntgt5hy9 190 10 3 3 CD cord-280571-ntgt5hy9 190 11 targets target NNS cord-280571-ntgt5hy9 190 12 plus plus CC cord-280571-ntgt5hy9 190 13 an an DT cord-280571-ntgt5hy9 190 14 internal internal JJ cord-280571-ntgt5hy9 190 15 control control NN cord-280571-ntgt5hy9 190 16 that that WDT cord-280571-ntgt5hy9 190 17 can can MD cord-280571-ntgt5hy9 190 18 be be VB cord-280571-ntgt5hy9 190 19 detected detect VBN cord-280571-ntgt5hy9 190 20 in in IN cord-280571-ntgt5hy9 190 21 a a DT cord-280571-ntgt5hy9 190 22 single single JJ cord-280571-ntgt5hy9 190 23 reaction reaction NN cord-280571-ntgt5hy9 190 24 . . . cord-280571-ntgt5hy9 191 1 Therefore therefore RB cord-280571-ntgt5hy9 191 2 , , , cord-280571-ntgt5hy9 191 3 a a DT cord-280571-ntgt5hy9 191 4 comprehensive comprehensive JJ cord-280571-ntgt5hy9 191 5 viral viral JJ cord-280571-ntgt5hy9 191 6 diagnostic diagnostic JJ cord-280571-ntgt5hy9 191 7 panel panel NN cord-280571-ntgt5hy9 191 8 requires require VBZ cord-280571-ntgt5hy9 191 9 multiple multiple JJ cord-280571-ntgt5hy9 191 10 PCRs pcr NNS cord-280571-ntgt5hy9 191 11 . . . cord-280571-ntgt5hy9 192 1 Multiple multiple JJ cord-280571-ntgt5hy9 192 2 PCRs pcr NNS cord-280571-ntgt5hy9 192 3 are be VBP cord-280571-ntgt5hy9 192 4 costly costly JJ cord-280571-ntgt5hy9 192 5 to to IN cord-280571-ntgt5hy9 192 6 the the DT cord-280571-ntgt5hy9 192 7 laboratory laboratory NN cord-280571-ntgt5hy9 192 8 in in IN cord-280571-ntgt5hy9 192 9 both both DT cord-280571-ntgt5hy9 192 10 technical technical JJ cord-280571-ntgt5hy9 192 11 time time NN cord-280571-ntgt5hy9 192 12 and and CC cord-280571-ntgt5hy9 192 13 reagent reagent NN cord-280571-ntgt5hy9 192 14 cost cost NN cord-280571-ntgt5hy9 192 15 . . . cord-280571-ntgt5hy9 193 1 However however RB cord-280571-ntgt5hy9 193 2 , , , cord-280571-ntgt5hy9 193 3 the the DT cord-280571-ntgt5hy9 193 4 limited limited JJ cord-280571-ntgt5hy9 193 5 panel panel NN cord-280571-ntgt5hy9 193 6 size size NN cord-280571-ntgt5hy9 193 7 could could MD cord-280571-ntgt5hy9 193 8 provide provide VB cord-280571-ntgt5hy9 193 9 a a DT cord-280571-ntgt5hy9 193 10 mix mix NN cord-280571-ntgt5hy9 193 11 - - HYPH cord-280571-ntgt5hy9 193 12 and and CC cord-280571-ntgt5hy9 193 13 - - HYPH cord-280571-ntgt5hy9 193 14 match match NN cord-280571-ntgt5hy9 193 15 test test NN cord-280571-ntgt5hy9 193 16 menu menu NN cord-280571-ntgt5hy9 193 17 , , , cord-280571-ntgt5hy9 193 18 allowing allow VBG cord-280571-ntgt5hy9 193 19 clinicians clinician NNS cord-280571-ntgt5hy9 193 20 the the DT cord-280571-ntgt5hy9 193 21 option option NN cord-280571-ntgt5hy9 193 22 of of IN cord-280571-ntgt5hy9 193 23 selecting select VBG cord-280571-ntgt5hy9 193 24 1 1 CD cord-280571-ntgt5hy9 193 25 or or CC cord-280571-ntgt5hy9 193 26 several several JJ cord-280571-ntgt5hy9 193 27 panels panel NNS cord-280571-ntgt5hy9 193 28 . . . cord-280571-ntgt5hy9 194 1 The the DT cord-280571-ntgt5hy9 194 2 first first JJ cord-280571-ntgt5hy9 194 3 - - HYPH cord-280571-ntgt5hy9 194 4 generation generation NN cord-280571-ntgt5hy9 194 5 Verigene Verigene NNP cord-280571-ntgt5hy9 194 6 Respiratory Respiratory NNP cord-280571-ntgt5hy9 194 7 Virus virus NN cord-280571-ntgt5hy9 194 8 Nucleic Nucleic NNP cord-280571-ntgt5hy9 194 9 Acid acid NN cord-280571-ntgt5hy9 194 10 Test test NN cord-280571-ntgt5hy9 194 11 ( ( -LRB- cord-280571-ntgt5hy9 194 12 VRNAT VRNAT NNP cord-280571-ntgt5hy9 194 13 ) ) -RRB- cord-280571-ntgt5hy9 194 14 was be VBD cord-280571-ntgt5hy9 194 15 cleared clear VBN cord-280571-ntgt5hy9 194 16 by by IN cord-280571-ntgt5hy9 194 17 the the DT cord-280571-ntgt5hy9 194 18 FDA FDA NNP cord-280571-ntgt5hy9 194 19 in in IN cord-280571-ntgt5hy9 194 20 May May NNP cord-280571-ntgt5hy9 194 21 2009 2009 CD cord-280571-ntgt5hy9 194 22 . . . cord-280571-ntgt5hy9 195 1 This this DT cord-280571-ntgt5hy9 195 2 test test NN cord-280571-ntgt5hy9 195 3 has have VBZ cord-280571-ntgt5hy9 195 4 been be VBN cord-280571-ntgt5hy9 195 5 replaced replace VBN cord-280571-ntgt5hy9 195 6 by by IN cord-280571-ntgt5hy9 195 7 the the DT cord-280571-ntgt5hy9 195 8 automated automate VBN cord-280571-ntgt5hy9 195 9 Verigene Verigene NNP cord-280571-ntgt5hy9 195 10 VRNAT VRNAT NNP cord-280571-ntgt5hy9 195 11 SP SP NNP cord-280571-ntgt5hy9 195 12 , , , cord-280571-ntgt5hy9 195 13 a a DT cord-280571-ntgt5hy9 195 14 CLIA CLIA NNP cord-280571-ntgt5hy9 195 15 moderately moderately RB cord-280571-ntgt5hy9 195 16 complex complex JJ cord-280571-ntgt5hy9 195 17 test test NN cord-280571-ntgt5hy9 195 18 that that WDT cord-280571-ntgt5hy9 195 19 is be VBZ cord-280571-ntgt5hy9 195 20 intended intend VBN cord-280571-ntgt5hy9 195 21 for for IN cord-280571-ntgt5hy9 195 22 the the DT cord-280571-ntgt5hy9 195 23 identification identification NN cord-280571-ntgt5hy9 195 24 of of IN cord-280571-ntgt5hy9 195 25 influenza influenza NN cord-280571-ntgt5hy9 195 26 A a NN cord-280571-ntgt5hy9 195 27 , , , cord-280571-ntgt5hy9 195 28 influenza influenza NN cord-280571-ntgt5hy9 195 29 B b NN cord-280571-ntgt5hy9 195 30 , , , cord-280571-ntgt5hy9 195 31 and and CC cord-280571-ntgt5hy9 195 32 RSV RSV NNP cord-280571-ntgt5hy9 195 33 ( ( -LRB- cord-280571-ntgt5hy9 195 34 types type NNS cord-280571-ntgt5hy9 195 35 A A NNP cord-280571-ntgt5hy9 195 36 and and CC cord-280571-ntgt5hy9 195 37 B b NN cord-280571-ntgt5hy9 195 38 inclusive inclusive JJ cord-280571-ntgt5hy9 195 39 ) ) -RRB- cord-280571-ntgt5hy9 195 40 from from IN cord-280571-ntgt5hy9 195 41 nasopharyngeal nasopharyngeal JJ cord-280571-ntgt5hy9 195 42 swab swab NN cord-280571-ntgt5hy9 195 43 specimens specimen NNS cord-280571-ntgt5hy9 195 44 placed place VBN cord-280571-ntgt5hy9 195 45 in in IN cord-280571-ntgt5hy9 195 46 viral viral JJ cord-280571-ntgt5hy9 195 47 transport transport NN cord-280571-ntgt5hy9 195 48 media medium NNS cord-280571-ntgt5hy9 195 49 . . . cord-280571-ntgt5hy9 196 1 The the DT cord-280571-ntgt5hy9 196 2 Verigene Verigene NNP cord-280571-ntgt5hy9 196 3 System System NNP cord-280571-ntgt5hy9 196 4 consists consist VBZ cord-280571-ntgt5hy9 196 5 of of IN cord-280571-ntgt5hy9 196 6 2 2 CD cord-280571-ntgt5hy9 196 7 instruments instrument NNS cord-280571-ntgt5hy9 196 8 ( ( -LRB- cord-280571-ntgt5hy9 196 9 the the DT cord-280571-ntgt5hy9 196 10 fully fully RB cord-280571-ntgt5hy9 196 11 automated automate VBN cord-280571-ntgt5hy9 196 12 Verigene Verigene NNP cord-280571-ntgt5hy9 196 13 Processor Processor NNP cord-280571-ntgt5hy9 196 14 and and CC cord-280571-ntgt5hy9 196 15 the the DT cord-280571-ntgt5hy9 196 16 Verigene Verigene NNP cord-280571-ntgt5hy9 196 17 Reader Reader NNP cord-280571-ntgt5hy9 196 18 ) ) -RRB- cord-280571-ntgt5hy9 196 19 and and CC cord-280571-ntgt5hy9 196 20 single single JJ cord-280571-ntgt5hy9 196 21 - - HYPH cord-280571-ntgt5hy9 196 22 use use NN cord-280571-ntgt5hy9 196 23 test test NN cord-280571-ntgt5hy9 196 24 cartridges cartridge NNS cord-280571-ntgt5hy9 196 25 ( ( -LRB- cord-280571-ntgt5hy9 196 26 Figure figure NN cord-280571-ntgt5hy9 196 27 2 2 CD cord-280571-ntgt5hy9 196 28 ) ) -RRB- cord-280571-ntgt5hy9 196 29 . . . cord-280571-ntgt5hy9 197 1 The the DT cord-280571-ntgt5hy9 197 2 entire entire JJ cord-280571-ntgt5hy9 197 3 test test NN cord-280571-ntgt5hy9 197 4 process process NN cord-280571-ntgt5hy9 197 5 only only RB cord-280571-ntgt5hy9 197 6 requires require VBZ cord-280571-ntgt5hy9 197 7 1 1 CD cord-280571-ntgt5hy9 197 8 user user NN cord-280571-ntgt5hy9 197 9 pipetting pipetting JJ cord-280571-ntgt5hy9 197 10 step step NN cord-280571-ntgt5hy9 197 11 , , , cord-280571-ntgt5hy9 197 12 less less JJR cord-280571-ntgt5hy9 197 13 than than IN cord-280571-ntgt5hy9 197 14 5 5 CD cord-280571-ntgt5hy9 197 15 min min NN cord-280571-ntgt5hy9 197 16 of of IN cord-280571-ntgt5hy9 197 17 technical technical JJ cord-280571-ntgt5hy9 197 18 handson handson JJ cord-280571-ntgt5hy9 197 19 time time NN cord-280571-ntgt5hy9 197 20 , , , cord-280571-ntgt5hy9 197 21 and and CC cord-280571-ntgt5hy9 197 22 a a DT cord-280571-ntgt5hy9 197 23 sample sample NN cord-280571-ntgt5hy9 197 24 - - HYPH cord-280571-ntgt5hy9 197 25 to to IN cord-280571-ntgt5hy9 197 26 - - HYPH cord-280571-ntgt5hy9 197 27 result result VB cord-280571-ntgt5hy9 197 28 turnaround turnaround NN cord-280571-ntgt5hy9 197 29 time time NN cord-280571-ntgt5hy9 197 30 of of IN cord-280571-ntgt5hy9 197 31 about about RB cord-280571-ntgt5hy9 197 32 3.5 3.5 CD cord-280571-ntgt5hy9 197 33 h. h. NN cord-280571-ntgt5hy9 198 1 The the DT cord-280571-ntgt5hy9 198 2 basis basis NN cord-280571-ntgt5hy9 198 3 of of IN cord-280571-ntgt5hy9 198 4 VRNATsp vrnatsp NN cord-280571-ntgt5hy9 198 5 is be VBZ cord-280571-ntgt5hy9 198 6 Nanosphere Nanosphere NNP cord-280571-ntgt5hy9 198 7 's 's POS cord-280571-ntgt5hy9 198 8 proprietary proprietary JJ cord-280571-ntgt5hy9 198 9 gold gold NN cord-280571-ntgt5hy9 198 10 nanoparticle nanoparticle NN cord-280571-ntgt5hy9 198 11 hybridization hybridization NN cord-280571-ntgt5hy9 198 12 technology technology NN cord-280571-ntgt5hy9 198 13 [ [ -LRB- cord-280571-ntgt5hy9 198 14 41 41 CD cord-280571-ntgt5hy9 198 15 ] ] -RRB- cord-280571-ntgt5hy9 198 16 . . . cord-280571-ntgt5hy9 199 1 The the DT cord-280571-ntgt5hy9 199 2 gold gold NN cord-280571-ntgt5hy9 199 3 nanoparticles nanoparticle NNS cord-280571-ntgt5hy9 199 4 contain contain VBP cord-280571-ntgt5hy9 199 5 a a DT cord-280571-ntgt5hy9 199 6 high high JJ cord-280571-ntgt5hy9 199 7 density density NN cord-280571-ntgt5hy9 199 8 ( ( -LRB- cord-280571-ntgt5hy9 199 9 200 200 CD cord-280571-ntgt5hy9 199 10 ) ) -RRB- cord-280571-ntgt5hy9 199 11 of of IN cord-280571-ntgt5hy9 199 12 sequence sequence NN cord-280571-ntgt5hy9 199 13 - - HYPH cord-280571-ntgt5hy9 199 14 specific specific JJ cord-280571-ntgt5hy9 199 15 oligonucleotides oligonucleotide NNS cord-280571-ntgt5hy9 199 16 with with IN cord-280571-ntgt5hy9 199 17 a a DT cord-280571-ntgt5hy9 199 18 high high JJ cord-280571-ntgt5hy9 199 19 affinity affinity NN cord-280571-ntgt5hy9 199 20 for for IN cord-280571-ntgt5hy9 199 21 complementary complementary JJ cord-280571-ntgt5hy9 199 22 DNA dna NN cord-280571-ntgt5hy9 199 23 , , , cord-280571-ntgt5hy9 199 24 which which WDT cord-280571-ntgt5hy9 199 25 allows allow VBZ cord-280571-ntgt5hy9 199 26 for for IN cord-280571-ntgt5hy9 199 27 very very RB cord-280571-ntgt5hy9 199 28 efficient efficient JJ cord-280571-ntgt5hy9 199 29 hybridization hybridization NN cord-280571-ntgt5hy9 199 30 kinetics kinetics NN cord-280571-ntgt5hy9 199 31 . . . cord-280571-ntgt5hy9 200 1 The the DT cord-280571-ntgt5hy9 200 2 clinical clinical JJ cord-280571-ntgt5hy9 200 3 sample sample NN cord-280571-ntgt5hy9 200 4 is be VBZ cord-280571-ntgt5hy9 200 5 pipetted pipette VBN cord-280571-ntgt5hy9 200 6 into into IN cord-280571-ntgt5hy9 200 7 a a DT cord-280571-ntgt5hy9 200 8 single single JJ cord-280571-ntgt5hy9 200 9 - - HYPH cord-280571-ntgt5hy9 200 10 use use NN cord-280571-ntgt5hy9 200 11 extraction extraction NN cord-280571-ntgt5hy9 200 12 tray tray NN cord-280571-ntgt5hy9 200 13 , , , cord-280571-ntgt5hy9 200 14 which which WDT cord-280571-ntgt5hy9 200 15 is be VBZ cord-280571-ntgt5hy9 200 16 loaded load VBN cord-280571-ntgt5hy9 200 17 into into IN cord-280571-ntgt5hy9 200 18 the the DT cord-280571-ntgt5hy9 200 19 Verigene Verigene NNP cord-280571-ntgt5hy9 200 20 processing processing NN cord-280571-ntgt5hy9 200 21 unit unit NN cord-280571-ntgt5hy9 200 22 . . . cord-280571-ntgt5hy9 201 1 Chaotropic Chaotropic NNP cord-280571-ntgt5hy9 201 2 agents agent NNS cord-280571-ntgt5hy9 201 3 are be VBP cord-280571-ntgt5hy9 201 4 added add VBN cord-280571-ntgt5hy9 201 5 to to IN cord-280571-ntgt5hy9 201 6 the the DT cord-280571-ntgt5hy9 201 7 sample sample NN cord-280571-ntgt5hy9 201 8 to to TO cord-280571-ntgt5hy9 201 9 lyse lyse VB cord-280571-ntgt5hy9 201 10 cells cell NNS cord-280571-ntgt5hy9 201 11 , , , cord-280571-ntgt5hy9 201 12 viral viral JJ cord-280571-ntgt5hy9 201 13 particles particle NNS cord-280571-ntgt5hy9 201 14 , , , cord-280571-ntgt5hy9 201 15 and and CC cord-280571-ntgt5hy9 201 16 an an DT cord-280571-ntgt5hy9 201 17 internal internal JJ cord-280571-ntgt5hy9 201 18 control control NN cord-280571-ntgt5hy9 201 19 ( ( -LRB- cord-280571-ntgt5hy9 201 20 MS2 MS2 NNP cord-280571-ntgt5hy9 201 21 phage phage NN cord-280571-ntgt5hy9 201 22 ) ) -RRB- cord-280571-ntgt5hy9 201 23 that that WDT cord-280571-ntgt5hy9 201 24 is be VBZ cord-280571-ntgt5hy9 201 25 added add VBN cord-280571-ntgt5hy9 201 26 prior prior RB cord-280571-ntgt5hy9 201 27 to to IN cord-280571-ntgt5hy9 201 28 the the DT cord-280571-ntgt5hy9 201 29 extraction extraction NN cord-280571-ntgt5hy9 201 30 step step NN cord-280571-ntgt5hy9 201 31 . . . cord-280571-ntgt5hy9 202 1 The the DT cord-280571-ntgt5hy9 202 2 released release VBN cord-280571-ntgt5hy9 202 3 nucleic nucleic JJ cord-280571-ntgt5hy9 202 4 acids acid NNS cord-280571-ntgt5hy9 202 5 are be VBP cord-280571-ntgt5hy9 202 6 then then RB cord-280571-ntgt5hy9 202 7 captured capture VBN cord-280571-ntgt5hy9 202 8 on on IN cord-280571-ntgt5hy9 202 9 magnetic magnetic JJ cord-280571-ntgt5hy9 202 10 microparticles microparticle NNS cord-280571-ntgt5hy9 202 11 ( ( -LRB- cord-280571-ntgt5hy9 202 12 MMPs MMPs NNP cord-280571-ntgt5hy9 202 13 ) ) -RRB- cord-280571-ntgt5hy9 202 14 . . . cord-280571-ntgt5hy9 203 1 The the DT cord-280571-ntgt5hy9 203 2 MMP MMP NNP cord-280571-ntgt5hy9 203 3 - - HYPH cord-280571-ntgt5hy9 203 4 bound bind VBN cord-280571-ntgt5hy9 203 5 nucleic nucleic JJ cord-280571-ntgt5hy9 203 6 acids acid NNS cord-280571-ntgt5hy9 203 7 are be VBP cord-280571-ntgt5hy9 203 8 washed wash VBN cord-280571-ntgt5hy9 203 9 , , , cord-280571-ntgt5hy9 203 10 and and CC cord-280571-ntgt5hy9 203 11 the the DT cord-280571-ntgt5hy9 203 12 purified purify VBN cord-280571-ntgt5hy9 203 13 nucleic nucleic JJ cord-280571-ntgt5hy9 203 14 acids acid NNS cord-280571-ntgt5hy9 203 15 are be VBP cord-280571-ntgt5hy9 203 16 eluted elute VBN cord-280571-ntgt5hy9 203 17 from from IN cord-280571-ntgt5hy9 203 18 the the DT cord-280571-ntgt5hy9 203 19 MMPs mmp NNS cord-280571-ntgt5hy9 203 20 and and CC cord-280571-ntgt5hy9 203 21 transferred transfer VBN cord-280571-ntgt5hy9 203 22 to to IN cord-280571-ntgt5hy9 203 23 the the DT cord-280571-ntgt5hy9 203 24 amplification amplification NN cord-280571-ntgt5hy9 203 25 tray tray NN cord-280571-ntgt5hy9 203 26 . . . cord-280571-ntgt5hy9 204 1 A a DT cord-280571-ntgt5hy9 204 2 1-step 1-step CD cord-280571-ntgt5hy9 204 3 RT RT NNP cord-280571-ntgt5hy9 204 4 - - HYPH cord-280571-ntgt5hy9 204 5 PCR PCR NNP cord-280571-ntgt5hy9 204 6 is be VBZ cord-280571-ntgt5hy9 204 7 performed perform VBN cord-280571-ntgt5hy9 204 8 using use VBG cord-280571-ntgt5hy9 204 9 primers primer NNS cord-280571-ntgt5hy9 204 10 that that WDT cord-280571-ntgt5hy9 204 11 target target VBP cord-280571-ntgt5hy9 204 12 the the DT cord-280571-ntgt5hy9 204 13 influenza influenza NN cord-280571-ntgt5hy9 204 14 A a DT cord-280571-ntgt5hy9 204 15 matrix matrix NN cord-280571-ntgt5hy9 204 16 gene gene NN cord-280571-ntgt5hy9 204 17 , , , cord-280571-ntgt5hy9 204 18 the the DT cord-280571-ntgt5hy9 204 19 influenza influenza NN cord-280571-ntgt5hy9 204 20 B b NN cord-280571-ntgt5hy9 204 21 matrix matrix NN cord-280571-ntgt5hy9 204 22 gene gene NN cord-280571-ntgt5hy9 204 23 and and CC cord-280571-ntgt5hy9 204 24 nonstructural nonstructural JJ cord-280571-ntgt5hy9 204 25 gene gene NN cord-280571-ntgt5hy9 204 26 , , , cord-280571-ntgt5hy9 204 27 and and CC cord-280571-ntgt5hy9 204 28 the the DT cord-280571-ntgt5hy9 204 29 RSV RSV NNP cord-280571-ntgt5hy9 204 30 L L NNP cord-280571-ntgt5hy9 204 31 gene gene NN cord-280571-ntgt5hy9 204 32 and and CC cord-280571-ntgt5hy9 204 33 F F NNP cord-280571-ntgt5hy9 204 34 gene gene NN cord-280571-ntgt5hy9 204 35 . . . cord-280571-ntgt5hy9 205 1 The the DT cord-280571-ntgt5hy9 205 2 RT RT NNP cord-280571-ntgt5hy9 205 3 - - HYPH cord-280571-ntgt5hy9 205 4 PCR PCR NNP cord-280571-ntgt5hy9 205 5 reaction reaction NN cord-280571-ntgt5hy9 205 6 is be VBZ cord-280571-ntgt5hy9 205 7 followed follow VBN cord-280571-ntgt5hy9 205 8 by by IN cord-280571-ntgt5hy9 205 9 the the DT cord-280571-ntgt5hy9 205 10 primary primary JJ cord-280571-ntgt5hy9 205 11 hybridization hybridization NN cord-280571-ntgt5hy9 205 12 step step NN cord-280571-ntgt5hy9 205 13 . . . cord-280571-ntgt5hy9 206 1 During during IN cord-280571-ntgt5hy9 206 2 primary primary JJ cord-280571-ntgt5hy9 206 3 hybridization hybridization NN cord-280571-ntgt5hy9 206 4 , , , cord-280571-ntgt5hy9 206 5 target target NN cord-280571-ntgt5hy9 206 6 DNA DNA NNP cord-280571-ntgt5hy9 206 7 is be VBZ cord-280571-ntgt5hy9 206 8 simultaneously simultaneously RB cord-280571-ntgt5hy9 206 9 hybridized hybridize VBN cord-280571-ntgt5hy9 206 10 to to TO cord-280571-ntgt5hy9 206 11 target target VB cord-280571-ntgt5hy9 206 12 - - HYPH cord-280571-ntgt5hy9 206 13 specific specific JJ cord-280571-ntgt5hy9 206 14 capture capture NN cord-280571-ntgt5hy9 206 15 DNA dna NN cord-280571-ntgt5hy9 206 16 oligonucleotides oligonucleotide NNS cord-280571-ntgt5hy9 206 17 arrayed array VBN cord-280571-ntgt5hy9 206 18 in in IN cord-280571-ntgt5hy9 206 19 replicate replicate NN cord-280571-ntgt5hy9 206 20 on on IN cord-280571-ntgt5hy9 206 21 a a DT cord-280571-ntgt5hy9 206 22 solid solid JJ cord-280571-ntgt5hy9 206 23 substrate substrate NN cord-280571-ntgt5hy9 206 24 ( ( -LRB- cord-280571-ntgt5hy9 206 25 a a DT cord-280571-ntgt5hy9 206 26 microarray microarray NN cord-280571-ntgt5hy9 206 27 ) ) -RRB- cord-280571-ntgt5hy9 206 28 and and CC cord-280571-ntgt5hy9 206 29 to to TO cord-280571-ntgt5hy9 206 30 target target VB cord-280571-ntgt5hy9 206 31 - - HYPH cord-280571-ntgt5hy9 206 32 specific specific JJ cord-280571-ntgt5hy9 206 33 mediator mediator NN cord-280571-ntgt5hy9 206 34 DNA dna NN cord-280571-ntgt5hy9 206 35 oligonucleotides oligonucleotide NNS cord-280571-ntgt5hy9 206 36 . . . cord-280571-ntgt5hy9 207 1 After after IN cord-280571-ntgt5hy9 207 2 removal removal NN cord-280571-ntgt5hy9 207 3 of of IN cord-280571-ntgt5hy9 207 4 uncaptured uncaptured JJ cord-280571-ntgt5hy9 207 5 target target NN cord-280571-ntgt5hy9 207 6 nucleic nucleic JJ cord-280571-ntgt5hy9 207 7 acids acid NNS cord-280571-ntgt5hy9 207 8 and and CC cord-280571-ntgt5hy9 207 9 unhybridized unhybridized JJ cord-280571-ntgt5hy9 207 10 mediator mediator NN cord-280571-ntgt5hy9 207 11 oligonucleotides oligonucleotide NNS cord-280571-ntgt5hy9 207 12 , , , cord-280571-ntgt5hy9 207 13 the the DT cord-280571-ntgt5hy9 207 14 process process NN cord-280571-ntgt5hy9 207 15 continues continue VBZ cord-280571-ntgt5hy9 207 16 with with IN cord-280571-ntgt5hy9 207 17 the the DT cord-280571-ntgt5hy9 207 18 secondary secondary JJ cord-280571-ntgt5hy9 207 19 hybridization hybridization NN cord-280571-ntgt5hy9 207 20 . . . cord-280571-ntgt5hy9 208 1 Each each DT cord-280571-ntgt5hy9 208 2 microarray microarray NN cord-280571-ntgt5hy9 208 3 spot spot NN cord-280571-ntgt5hy9 208 4 , , , cord-280571-ntgt5hy9 208 5 where where WRB cord-280571-ntgt5hy9 208 6 an an DT cord-280571-ntgt5hy9 208 7 appropriate appropriate JJ cord-280571-ntgt5hy9 208 8 target target NN cord-280571-ntgt5hy9 208 9 is be VBZ cord-280571-ntgt5hy9 208 10 hybridized hybridize VBN cord-280571-ntgt5hy9 208 11 to to TO cord-280571-ntgt5hy9 208 12 capture capture VB cord-280571-ntgt5hy9 208 13 both both CC cord-280571-ntgt5hy9 208 14 an an DT cord-280571-ntgt5hy9 208 15 oligonucleotide oligonucleotide NN cord-280571-ntgt5hy9 208 16 and and CC cord-280571-ntgt5hy9 208 17 a a DT cord-280571-ntgt5hy9 208 18 mediator mediator NN cord-280571-ntgt5hy9 208 19 oligonucleotide oligonucleotide NN cord-280571-ntgt5hy9 208 20 , , , cord-280571-ntgt5hy9 208 21 is be VBZ cord-280571-ntgt5hy9 208 22 saturated saturate VBN cord-280571-ntgt5hy9 208 23 with with IN cord-280571-ntgt5hy9 208 24 silver silver JJ cord-280571-ntgt5hy9 208 25 - - HYPH cord-280571-ntgt5hy9 208 26 coated coated JJ cord-280571-ntgt5hy9 208 27 gold gold NN cord-280571-ntgt5hy9 208 28 nanoparticle nanoparticle NN cord-280571-ntgt5hy9 208 29 probes probe NNS cord-280571-ntgt5hy9 208 30 . . . cord-280571-ntgt5hy9 209 1 After after IN cord-280571-ntgt5hy9 209 2 hybridization hybridization NN cord-280571-ntgt5hy9 209 3 , , , cord-280571-ntgt5hy9 209 4 the the DT cord-280571-ntgt5hy9 209 5 cartridge cartridge NN cord-280571-ntgt5hy9 209 6 is be VBZ cord-280571-ntgt5hy9 209 7 removed remove VBN cord-280571-ntgt5hy9 209 8 from from IN cord-280571-ntgt5hy9 209 9 the the DT cord-280571-ntgt5hy9 209 10 processor processor NN cord-280571-ntgt5hy9 209 11 unit unit NN cord-280571-ntgt5hy9 209 12 and and CC cord-280571-ntgt5hy9 209 13 the the DT cord-280571-ntgt5hy9 209 14 glass glass NN cord-280571-ntgt5hy9 209 15 slide slide NN cord-280571-ntgt5hy9 209 16 ( ( -LRB- cord-280571-ntgt5hy9 209 17 microarray microarray NN cord-280571-ntgt5hy9 209 18 ) ) -RRB- cord-280571-ntgt5hy9 209 19 is be VBZ cord-280571-ntgt5hy9 209 20 separated separate VBN cord-280571-ntgt5hy9 209 21 from from IN cord-280571-ntgt5hy9 209 22 the the DT cord-280571-ntgt5hy9 209 23 cartridge cartridge NN cord-280571-ntgt5hy9 209 24 and and CC cord-280571-ntgt5hy9 209 25 inserted insert VBD cord-280571-ntgt5hy9 209 26 into into IN cord-280571-ntgt5hy9 209 27 the the DT cord-280571-ntgt5hy9 209 28 Verigene Verigene NNP cord-280571-ntgt5hy9 209 29 Reader Reader NNP cord-280571-ntgt5hy9 209 30 . . . cord-280571-ntgt5hy9 210 1 A a DT cord-280571-ntgt5hy9 210 2 light light JJ cord-280571-ntgt5hy9 210 3 - - HYPH cord-280571-ntgt5hy9 210 4 scattering scattering NN cord-280571-ntgt5hy9 210 5 technique technique NN cord-280571-ntgt5hy9 210 6 , , , cord-280571-ntgt5hy9 210 7 in in IN cord-280571-ntgt5hy9 210 8 which which WDT cord-280571-ntgt5hy9 210 9 the the DT cord-280571-ntgt5hy9 210 10 slide slide NN cord-280571-ntgt5hy9 210 11 is be VBZ cord-280571-ntgt5hy9 210 12 illuminated illuminate VBN cord-280571-ntgt5hy9 210 13 internally internally RB cord-280571-ntgt5hy9 210 14 with with IN cord-280571-ntgt5hy9 210 15 light light JJ cord-280571-ntgt5hy9 210 16 parallel parallel JJ cord-280571-ntgt5hy9 210 17 to to IN cord-280571-ntgt5hy9 210 18 the the DT cord-280571-ntgt5hy9 210 19 slide slide NN cord-280571-ntgt5hy9 210 20 surface surface NN cord-280571-ntgt5hy9 210 21 , , , cord-280571-ntgt5hy9 210 22 is be VBZ cord-280571-ntgt5hy9 210 23 used use VBN cord-280571-ntgt5hy9 210 24 to to TO cord-280571-ntgt5hy9 210 25 analyze analyze VB cord-280571-ntgt5hy9 210 26 the the DT cord-280571-ntgt5hy9 210 27 results result NNS cord-280571-ntgt5hy9 210 28 . . . cord-280571-ntgt5hy9 211 1 Spots spot NNS cord-280571-ntgt5hy9 211 2 where where WRB cord-280571-ntgt5hy9 211 3 silverenhanced silverenhanced JJ cord-280571-ntgt5hy9 211 4 gold gold NN cord-280571-ntgt5hy9 211 5 nanoparticle nanoparticle NN cord-280571-ntgt5hy9 211 6 probes probe NNS cord-280571-ntgt5hy9 211 7 are be VBP cord-280571-ntgt5hy9 211 8 present present JJ cord-280571-ntgt5hy9 211 9 scatter scatter NN cord-280571-ntgt5hy9 211 10 this this DT cord-280571-ntgt5hy9 211 11 light light NN cord-280571-ntgt5hy9 211 12 , , , cord-280571-ntgt5hy9 211 13 and and CC cord-280571-ntgt5hy9 211 14 the the DT cord-280571-ntgt5hy9 211 15 light light JJ cord-280571-ntgt5hy9 211 16 scatter scatter NN cord-280571-ntgt5hy9 211 17 is be VBZ cord-280571-ntgt5hy9 211 18 detected detect VBN cord-280571-ntgt5hy9 211 19 optically optically RB cord-280571-ntgt5hy9 211 20 and and CC cord-280571-ntgt5hy9 211 21 translated translate VBN cord-280571-ntgt5hy9 211 22 into into IN cord-280571-ntgt5hy9 211 23 a a DT cord-280571-ntgt5hy9 211 24 measurable measurable JJ cord-280571-ntgt5hy9 211 25 signal signal NN cord-280571-ntgt5hy9 211 26 . . . cord-280571-ntgt5hy9 212 1 The the DT cord-280571-ntgt5hy9 212 2 performance performance NN cord-280571-ntgt5hy9 212 3 characteristics characteristic NNS cord-280571-ntgt5hy9 212 4 of of IN cord-280571-ntgt5hy9 212 5 the the DT cord-280571-ntgt5hy9 212 6 first first JJ cord-280571-ntgt5hy9 212 7 - - HYPH cord-280571-ntgt5hy9 212 8 generation generation NN cord-280571-ntgt5hy9 212 9 VRNAT VRNAT NNP cord-280571-ntgt5hy9 212 10 assay assay NN cord-280571-ntgt5hy9 212 11 were be VBD cord-280571-ntgt5hy9 212 12 established establish VBN cord-280571-ntgt5hy9 212 13 during during IN cord-280571-ntgt5hy9 212 14 the the DT cord-280571-ntgt5hy9 212 15 clinical clinical JJ cord-280571-ntgt5hy9 212 16 trials trial NNS cord-280571-ntgt5hy9 212 17 for for IN cord-280571-ntgt5hy9 212 18 IVD IVD NNP cord-280571-ntgt5hy9 212 19 device device NN cord-280571-ntgt5hy9 212 20 clearance clearance NN cord-280571-ntgt5hy9 212 21 . . . cord-280571-ntgt5hy9 213 1 VRNAT VRNAT NNP cord-280571-ntgt5hy9 213 2 was be VBD cord-280571-ntgt5hy9 213 3 compared compare VBN cord-280571-ntgt5hy9 213 4 with with IN cord-280571-ntgt5hy9 213 5 viral viral JJ cord-280571-ntgt5hy9 213 6 culture culture NN cord-280571-ntgt5hy9 213 7 / / SYM cord-280571-ntgt5hy9 213 8 DFA DFA NNP cord-280571-ntgt5hy9 213 9 testing testing NN cord-280571-ntgt5hy9 213 10 with with IN cord-280571-ntgt5hy9 213 11 bidirectional bidirectional JJ cord-280571-ntgt5hy9 213 12 sequencing sequencing NN cord-280571-ntgt5hy9 213 13 to to TO cord-280571-ntgt5hy9 213 14 resolve resolve VB cord-280571-ntgt5hy9 213 15 discordant discordant JJ cord-280571-ntgt5hy9 213 16 results result NNS cord-280571-ntgt5hy9 213 17 . . . cord-280571-ntgt5hy9 214 1 Test test NN cord-280571-ntgt5hy9 214 2 sensitivities sensitivity NNS cord-280571-ntgt5hy9 214 3 and and CC cord-280571-ntgt5hy9 214 4 specificities specificity NNS cord-280571-ntgt5hy9 214 5 for for IN cord-280571-ntgt5hy9 214 6 the the DT cord-280571-ntgt5hy9 214 7 detection detection NN cord-280571-ntgt5hy9 214 8 of of IN cord-280571-ntgt5hy9 214 9 influenza influenza NN cord-280571-ntgt5hy9 214 10 A a NN cord-280571-ntgt5hy9 214 11 were be VBD cord-280571-ntgt5hy9 214 12 100 100 CD cord-280571-ntgt5hy9 214 13 % % NN cord-280571-ntgt5hy9 214 14 and and CC cord-280571-ntgt5hy9 214 15 99.8 99.8 CD cord-280571-ntgt5hy9 214 16 % % NN cord-280571-ntgt5hy9 214 17 , , , cord-280571-ntgt5hy9 214 18 respectively respectively RB cord-280571-ntgt5hy9 214 19 ; ; : cord-280571-ntgt5hy9 214 20 for for IN cord-280571-ntgt5hy9 214 21 influenza influenza NN cord-280571-ntgt5hy9 214 22 B B NNP cord-280571-ntgt5hy9 214 23 were be VBD cord-280571-ntgt5hy9 214 24 100 100 CD cord-280571-ntgt5hy9 214 25 % % NN cord-280571-ntgt5hy9 214 26 and and CC cord-280571-ntgt5hy9 214 27 99.1 99.1 CD cord-280571-ntgt5hy9 214 28 % % NN cord-280571-ntgt5hy9 214 29 , , , cord-280571-ntgt5hy9 214 30 respectively respectively RB cord-280571-ntgt5hy9 214 31 ; ; : cord-280571-ntgt5hy9 214 32 and and CC cord-280571-ntgt5hy9 214 33 for for IN cord-280571-ntgt5hy9 214 34 RSV RSV NNP cord-280571-ntgt5hy9 214 35 were be VBD cord-280571-ntgt5hy9 214 36 95.7 95.7 CD cord-280571-ntgt5hy9 214 37 % % NN cord-280571-ntgt5hy9 214 38 and and CC cord-280571-ntgt5hy9 214 39 98.2 98.2 CD cord-280571-ntgt5hy9 214 40 % % NN cord-280571-ntgt5hy9 214 41 , , , cord-280571-ntgt5hy9 214 42 respectively respectively RB cord-280571-ntgt5hy9 214 43 [ [ -LRB- cord-280571-ntgt5hy9 214 44 106 106 CD cord-280571-ntgt5hy9 214 45 ] ] -RRB- cord-280571-ntgt5hy9 214 46 . . . cord-280571-ntgt5hy9 215 1 Comparison comparison NN cord-280571-ntgt5hy9 215 2 of of IN cord-280571-ntgt5hy9 215 3 VRNAT VRNAT NNP cord-280571-ntgt5hy9 215 4 with with IN cord-280571-ntgt5hy9 215 5 VRNATsp VRNATsp NNP cord-280571-ntgt5hy9 215 6 revealed reveal VBD cord-280571-ntgt5hy9 215 7 an an DT cord-280571-ntgt5hy9 215 8 overall overall JJ cord-280571-ntgt5hy9 215 9 positive positive JJ cord-280571-ntgt5hy9 215 10 agreement agreement NN cord-280571-ntgt5hy9 215 11 of of IN cord-280571-ntgt5hy9 215 12 97.9 97.9 CD cord-280571-ntgt5hy9 215 13 % % NN cord-280571-ntgt5hy9 215 14 and and CC cord-280571-ntgt5hy9 215 15 a a DT cord-280571-ntgt5hy9 215 16 negative negative JJ cord-280571-ntgt5hy9 215 17 agreement agreement NN cord-280571-ntgt5hy9 215 18 value value NN cord-280571-ntgt5hy9 215 19 of of IN cord-280571-ntgt5hy9 215 20 100 100 CD cord-280571-ntgt5hy9 215 21 % % NN cord-280571-ntgt5hy9 215 22 [ [ -LRB- cord-280571-ntgt5hy9 215 23 107 107 CD cord-280571-ntgt5hy9 215 24 ] ] -RRB- cord-280571-ntgt5hy9 215 25 . . . cord-280571-ntgt5hy9 216 1 The the DT cord-280571-ntgt5hy9 216 2 benefits benefit NNS cord-280571-ntgt5hy9 216 3 of of IN cord-280571-ntgt5hy9 216 4 the the DT cord-280571-ntgt5hy9 216 5 VRNATsp VRNATsp NNP cord-280571-ntgt5hy9 216 6 System System NNP cord-280571-ntgt5hy9 216 7 include include VBP cord-280571-ntgt5hy9 216 8 the the DT cord-280571-ntgt5hy9 216 9 scalability scalability NN cord-280571-ntgt5hy9 216 10 of of IN cord-280571-ntgt5hy9 216 11 the the DT cord-280571-ntgt5hy9 216 12 system system NN cord-280571-ntgt5hy9 216 13 ( ( -LRB- cord-280571-ntgt5hy9 216 14 addition addition NN cord-280571-ntgt5hy9 216 15 of of IN cord-280571-ntgt5hy9 216 16 multiple multiple JJ cord-280571-ntgt5hy9 216 17 processors processor NNS cord-280571-ntgt5hy9 216 18 and and CC cord-280571-ntgt5hy9 216 19 readers reader NNS cord-280571-ntgt5hy9 216 20 ) ) -RRB- cord-280571-ntgt5hy9 216 21 , , , cord-280571-ntgt5hy9 216 22 individual individual JJ cord-280571-ntgt5hy9 216 23 sample sample NN cord-280571-ntgt5hy9 216 24 processing processing NN cord-280571-ntgt5hy9 216 25 with with IN cord-280571-ntgt5hy9 216 26 random random JJ cord-280571-ntgt5hy9 216 27 access access NN cord-280571-ntgt5hy9 216 28 format format NN cord-280571-ntgt5hy9 216 29 , , , cord-280571-ntgt5hy9 216 30 minimal minimal JJ cord-280571-ntgt5hy9 216 31 hands hand NNS cord-280571-ntgt5hy9 216 32 - - HYPH cord-280571-ntgt5hy9 216 33 on on RP cord-280571-ntgt5hy9 216 34 time time NN cord-280571-ntgt5hy9 216 35 , , , cord-280571-ntgt5hy9 216 36 and and CC cord-280571-ntgt5hy9 216 37 minimal minimal JJ cord-280571-ntgt5hy9 216 38 technical technical JJ cord-280571-ntgt5hy9 216 39 expertise expertise NN cord-280571-ntgt5hy9 216 40 required require VBN cord-280571-ntgt5hy9 216 41 to to TO cord-280571-ntgt5hy9 216 42 perform perform VB cord-280571-ntgt5hy9 216 43 the the DT cord-280571-ntgt5hy9 216 44 test test NN cord-280571-ntgt5hy9 216 45 . . . cord-280571-ntgt5hy9 217 1 Because because IN cord-280571-ntgt5hy9 217 2 this this DT cord-280571-ntgt5hy9 217 3 test test NN cord-280571-ntgt5hy9 217 4 is be VBZ cord-280571-ntgt5hy9 217 5 CLIA CLIA NNP cord-280571-ntgt5hy9 217 6 moderate moderate JJ cord-280571-ntgt5hy9 217 7 complexity complexity NN cord-280571-ntgt5hy9 217 8 , , , cord-280571-ntgt5hy9 217 9 trained train VBN cord-280571-ntgt5hy9 217 10 laboratory laboratory NN cord-280571-ntgt5hy9 217 11 technicians technician NNS cord-280571-ntgt5hy9 217 12 could could MD cord-280571-ntgt5hy9 217 13 perform perform VB cord-280571-ntgt5hy9 217 14 the the DT cord-280571-ntgt5hy9 217 15 testing testing NN cord-280571-ntgt5hy9 217 16 . . . cord-280571-ntgt5hy9 218 1 This this DT cord-280571-ntgt5hy9 218 2 test test NN cord-280571-ntgt5hy9 218 3 would would MD cord-280571-ntgt5hy9 218 4 be be VB cord-280571-ntgt5hy9 218 5 well well RB cord-280571-ntgt5hy9 218 6 suited suited JJ cord-280571-ntgt5hy9 218 7 for for IN cord-280571-ntgt5hy9 218 8 small small JJ cord-280571-ntgt5hy9 218 9 - - HYPH cord-280571-ntgt5hy9 218 10 to to TO cord-280571-ntgt5hy9 218 11 medium medium JJ cord-280571-ntgt5hy9 218 12 - - HYPH cord-280571-ntgt5hy9 218 13 sized sized JJ cord-280571-ntgt5hy9 218 14 laboratories laboratory NNS cord-280571-ntgt5hy9 218 15 , , , cord-280571-ntgt5hy9 218 16 in in IN cord-280571-ntgt5hy9 218 17 particular particular JJ cord-280571-ntgt5hy9 218 18 for for IN cord-280571-ntgt5hy9 218 19 laboratories laboratory NNS cord-280571-ntgt5hy9 218 20 with with IN cord-280571-ntgt5hy9 218 21 little little JJ cord-280571-ntgt5hy9 218 22 or or CC cord-280571-ntgt5hy9 218 23 no no DT cord-280571-ntgt5hy9 218 24 molecular molecular JJ cord-280571-ntgt5hy9 218 25 testing testing NN cord-280571-ntgt5hy9 218 26 experience experience NN cord-280571-ntgt5hy9 218 27 . . . cord-280571-ntgt5hy9 219 1 Limitations limitation NNS cord-280571-ntgt5hy9 219 2 of of IN cord-280571-ntgt5hy9 219 3 the the DT cord-280571-ntgt5hy9 219 4 assay assay NN cord-280571-ntgt5hy9 219 5 include include VBP cord-280571-ntgt5hy9 219 6 the the DT cord-280571-ntgt5hy9 219 7 single single JJ cord-280571-ntgt5hy9 219 8 test test NN cord-280571-ntgt5hy9 219 9 format format NN cord-280571-ntgt5hy9 219 10 that that WDT cord-280571-ntgt5hy9 219 11 requires require VBZ cord-280571-ntgt5hy9 219 12 a a DT cord-280571-ntgt5hy9 219 13 dedicated dedicated JJ cord-280571-ntgt5hy9 219 14 processor processor NN cord-280571-ntgt5hy9 219 15 for for IN cord-280571-ntgt5hy9 219 16 each each DT cord-280571-ntgt5hy9 219 17 sample sample NN cord-280571-ntgt5hy9 219 18 for for IN cord-280571-ntgt5hy9 219 19 3 3 CD cord-280571-ntgt5hy9 219 20 - - SYM cord-280571-ntgt5hy9 219 21 3.5 3.5 CD cord-280571-ntgt5hy9 219 22 h. h. NN cord-280571-ntgt5hy9 219 23 Multiple multiple JJ cord-280571-ntgt5hy9 219 24 processor processor NN cord-280571-ntgt5hy9 219 25 units unit NNS cord-280571-ntgt5hy9 219 26 would would MD cord-280571-ntgt5hy9 219 27 be be VB cord-280571-ntgt5hy9 219 28 needed need VBN cord-280571-ntgt5hy9 219 29 for for IN cord-280571-ntgt5hy9 219 30 larger large JJR cord-280571-ntgt5hy9 219 31 volume volume NN cord-280571-ntgt5hy9 219 32 laboratories laboratory NNS cord-280571-ntgt5hy9 219 33 , , , cord-280571-ntgt5hy9 219 34 and and CC cord-280571-ntgt5hy9 219 35 the the DT cord-280571-ntgt5hy9 219 36 additional additional JJ cord-280571-ntgt5hy9 219 37 instrumentation instrumentation NN cord-280571-ntgt5hy9 219 38 would would MD cord-280571-ntgt5hy9 219 39 increase increase VB cord-280571-ntgt5hy9 219 40 costs cost NNS cord-280571-ntgt5hy9 219 41 for for IN cord-280571-ntgt5hy9 219 42 the the DT cord-280571-ntgt5hy9 219 43 lab lab NN cord-280571-ntgt5hy9 219 44 , , , cord-280571-ntgt5hy9 219 45 compared compare VBN cord-280571-ntgt5hy9 219 46 with with IN cord-280571-ntgt5hy9 219 47 using use VBG cord-280571-ntgt5hy9 219 48 an an DT cord-280571-ntgt5hy9 219 49 instrument instrument NN cord-280571-ntgt5hy9 219 50 that that WDT cord-280571-ntgt5hy9 219 51 can can MD cord-280571-ntgt5hy9 219 52 run run VB cord-280571-ntgt5hy9 219 53 multiple multiple JJ cord-280571-ntgt5hy9 219 54 tests test NNS cord-280571-ntgt5hy9 219 55 at at IN cord-280571-ntgt5hy9 219 56 a a DT cord-280571-ntgt5hy9 219 57 time time NN cord-280571-ntgt5hy9 219 58 . . . cord-280571-ntgt5hy9 220 1 Table table NN cord-280571-ntgt5hy9 220 2 2 2 CD cord-280571-ntgt5hy9 220 3 were be VBD cord-280571-ntgt5hy9 220 4 rescinded rescind VBN cord-280571-ntgt5hy9 220 5 as as IN cord-280571-ntgt5hy9 220 6 of of IN cord-280571-ntgt5hy9 220 7 23 23 CD cord-280571-ntgt5hy9 220 8 June June NNP cord-280571-ntgt5hy9 220 9 2010 2010 CD cord-280571-ntgt5hy9 220 10 . . . cord-280571-ntgt5hy9 221 1 As as IN cord-280571-ntgt5hy9 221 2 of of IN cord-280571-ntgt5hy9 221 3 July July NNP cord-280571-ntgt5hy9 221 4 2010 2010 CD cord-280571-ntgt5hy9 221 5 , , , cord-280571-ntgt5hy9 221 6 only only RB cord-280571-ntgt5hy9 221 7 2 2 CD cord-280571-ntgt5hy9 221 8 of of IN cord-280571-ntgt5hy9 221 9 these these DT cord-280571-ntgt5hy9 221 10 tests test NNS cord-280571-ntgt5hy9 221 11 have have VBP cord-280571-ntgt5hy9 221 12 received receive VBN cord-280571-ntgt5hy9 221 13 FDA FDA NNP cord-280571-ntgt5hy9 221 14 approval approval NN cord-280571-ntgt5hy9 221 15 for for IN cord-280571-ntgt5hy9 221 16 use use NN cord-280571-ntgt5hy9 221 17 as as IN cord-280571-ntgt5hy9 221 18 an an DT cord-280571-ntgt5hy9 221 19 IVD IVD NNP cord-280571-ntgt5hy9 221 20 device device NN cord-280571-ntgt5hy9 221 21 for for IN cord-280571-ntgt5hy9 221 22 the the DT cord-280571-ntgt5hy9 221 23 diagnosis diagnosis NN cord-280571-ntgt5hy9 221 24 of of IN cord-280571-ntgt5hy9 221 25 2009 2009 CD cord-280571-ntgt5hy9 221 26 pandemic pandemic NN cord-280571-ntgt5hy9 221 27 influenza influenza NN cord-280571-ntgt5hy9 221 28 A a DT cord-280571-ntgt5hy9 221 29 H1N1 H1N1 NNP cord-280571-ntgt5hy9 221 30 . . . cord-280571-ntgt5hy9 222 1 The the DT cord-280571-ntgt5hy9 222 2 first first JJ cord-280571-ntgt5hy9 222 3 test test NN cord-280571-ntgt5hy9 222 4 approved approve VBN cord-280571-ntgt5hy9 222 5 was be VBD cord-280571-ntgt5hy9 222 6 a a DT cord-280571-ntgt5hy9 222 7 new new JJ cord-280571-ntgt5hy9 222 8 optimized optimize VBN cord-280571-ntgt5hy9 222 9 CDC CDC NNP cord-280571-ntgt5hy9 222 10 H1N1 H1N1 NNP cord-280571-ntgt5hy9 222 11 assay assay NN cord-280571-ntgt5hy9 222 12 that that WDT cord-280571-ntgt5hy9 222 13 is be VBZ cord-280571-ntgt5hy9 222 14 available available JJ cord-280571-ntgt5hy9 222 15 in in IN cord-280571-ntgt5hy9 222 16 CDC CDC NNP cord-280571-ntgt5hy9 222 17 - - HYPH cord-280571-ntgt5hy9 222 18 qualified qualify VBN cord-280571-ntgt5hy9 222 19 laboratories laboratory NNS cord-280571-ntgt5hy9 222 20 . . . cord-280571-ntgt5hy9 223 1 The the DT cord-280571-ntgt5hy9 223 2 second second JJ cord-280571-ntgt5hy9 223 3 test test NN cord-280571-ntgt5hy9 223 4 is be VBZ cord-280571-ntgt5hy9 223 5 the the DT cord-280571-ntgt5hy9 223 6 Focus Focus NNP cord-280571-ntgt5hy9 223 7 Diagnostics Diagnostics NNP cord-280571-ntgt5hy9 223 8 Simplexa Simplexa NNP cord-280571-ntgt5hy9 224 1 Influenza Influenza NNP cord-280571-ntgt5hy9 224 2 A a DT cord-280571-ntgt5hy9 224 3 H1N1 H1N1 NNP cord-280571-ntgt5hy9 224 4 ( ( -LRB- cord-280571-ntgt5hy9 224 5 2009 2009 CD cord-280571-ntgt5hy9 224 6 ) ) -RRB- cord-280571-ntgt5hy9 224 7 , , , cord-280571-ntgt5hy9 224 8 which which WDT cord-280571-ntgt5hy9 224 9 is be VBZ cord-280571-ntgt5hy9 224 10 performed perform VBN cord-280571-ntgt5hy9 224 11 using use VBG cord-280571-ntgt5hy9 224 12 the the DT cord-280571-ntgt5hy9 224 13 3 3 CD cord-280571-ntgt5hy9 224 14 M M NNP cord-280571-ntgt5hy9 224 15 Integrated Integrated NNP cord-280571-ntgt5hy9 224 16 Cycler Cycler NNP cord-280571-ntgt5hy9 224 17 ( ( -LRB- cord-280571-ntgt5hy9 224 18 3 3 CD cord-280571-ntgt5hy9 224 19 M M NNP cord-280571-ntgt5hy9 224 20 ) ) -RRB- cord-280571-ntgt5hy9 224 21 . . . cord-280571-ntgt5hy9 225 1 The the DT cord-280571-ntgt5hy9 225 2 use use NN cord-280571-ntgt5hy9 225 3 of of IN cord-280571-ntgt5hy9 225 4 FDA FDA NNP cord-280571-ntgt5hy9 225 5 - - HYPH cord-280571-ntgt5hy9 225 6 approved approve VBN cord-280571-ntgt5hy9 225 7 / / SYM cord-280571-ntgt5hy9 225 8 cleared clear VBN cord-280571-ntgt5hy9 225 9 NAATs NAATs NNP cord-280571-ntgt5hy9 225 10 , , , cord-280571-ntgt5hy9 225 11 in in IN cord-280571-ntgt5hy9 225 12 contrast contrast NN cord-280571-ntgt5hy9 225 13 to to IN cord-280571-ntgt5hy9 225 14 laboratory laboratory NN cord-280571-ntgt5hy9 225 15 - - HYPH cord-280571-ntgt5hy9 225 16 developed develop VBN cord-280571-ntgt5hy9 225 17 tests test NNS cord-280571-ntgt5hy9 225 18 , , , cord-280571-ntgt5hy9 225 19 has have VBZ cord-280571-ntgt5hy9 225 20 substantial substantial JJ cord-280571-ntgt5hy9 225 21 benefits benefit NNS cord-280571-ntgt5hy9 225 22 for for IN cord-280571-ntgt5hy9 225 23 the the DT cord-280571-ntgt5hy9 225 24 laboratory laboratory NN cord-280571-ntgt5hy9 225 25 . . . cord-280571-ntgt5hy9 226 1 Approved approve VBN cord-280571-ntgt5hy9 226 2 tests test NNS cord-280571-ntgt5hy9 226 3 have have VBP cord-280571-ntgt5hy9 226 4 undergone undergo VBN cord-280571-ntgt5hy9 226 5 extensive extensive JJ cord-280571-ntgt5hy9 226 6 analytical analytical JJ cord-280571-ntgt5hy9 226 7 and and CC cord-280571-ntgt5hy9 226 8 clinical clinical JJ cord-280571-ntgt5hy9 226 9 validations validation NNS cord-280571-ntgt5hy9 226 10 during during IN cord-280571-ntgt5hy9 226 11 the the DT cord-280571-ntgt5hy9 226 12 course course NN cord-280571-ntgt5hy9 226 13 of of IN cord-280571-ntgt5hy9 226 14 the the DT cord-280571-ntgt5hy9 226 15 FDA FDA NNP cord-280571-ntgt5hy9 226 16 evaluations evaluation NNS cord-280571-ntgt5hy9 226 17 . . . cord-280571-ntgt5hy9 227 1 Therefore therefore RB cord-280571-ntgt5hy9 227 2 , , , cord-280571-ntgt5hy9 227 3 performance performance NN cord-280571-ntgt5hy9 227 4 parameters parameter NNS cord-280571-ntgt5hy9 227 5 are be VBP cord-280571-ntgt5hy9 227 6 well well RB cord-280571-ntgt5hy9 227 7 characterized characterize VBN cord-280571-ntgt5hy9 227 8 , , , cord-280571-ntgt5hy9 227 9 and and CC cord-280571-ntgt5hy9 227 10 the the DT cord-280571-ntgt5hy9 227 11 FDA FDA NNP cord-280571-ntgt5hy9 227 12 monitors monitor NNS cord-280571-ntgt5hy9 227 13 postapproval postapproval NN cord-280571-ntgt5hy9 227 14 performance performance NN cord-280571-ntgt5hy9 227 15 . . . cord-280571-ntgt5hy9 228 1 Most Most JJS cord-280571-ntgt5hy9 228 2 laboratories laboratory NNS cord-280571-ntgt5hy9 228 3 do do VBP cord-280571-ntgt5hy9 228 4 not not RB cord-280571-ntgt5hy9 228 5 have have VB cord-280571-ntgt5hy9 228 6 the the DT cord-280571-ntgt5hy9 228 7 expertise expertise NN cord-280571-ntgt5hy9 228 8 and and CC cord-280571-ntgt5hy9 228 9 resources resource NNS cord-280571-ntgt5hy9 228 10 to to TO cord-280571-ntgt5hy9 228 11 perform perform VB cord-280571-ntgt5hy9 228 12 extensive extensive JJ cord-280571-ntgt5hy9 228 13 ( ( -LRB- cord-280571-ntgt5hy9 228 14 Table Table NNP cord-280571-ntgt5hy9 228 15 3 3 CD cord-280571-ntgt5hy9 228 16 ) ) -RRB- cord-280571-ntgt5hy9 228 17 , , , cord-280571-ntgt5hy9 228 18 thereby thereby RB cord-280571-ntgt5hy9 228 19 saving save VBG cord-280571-ntgt5hy9 228 20 the the DT cord-280571-ntgt5hy9 228 21 laboratory laboratory NN cord-280571-ntgt5hy9 228 22 considerable considerable JJ cord-280571-ntgt5hy9 228 23 cost cost NN cord-280571-ntgt5hy9 228 24 and and CC cord-280571-ntgt5hy9 228 25 technical technical JJ cord-280571-ntgt5hy9 228 26 time time NN cord-280571-ntgt5hy9 228 27 . . . cord-280571-ntgt5hy9 229 1 The the DT cord-280571-ntgt5hy9 229 2 regulatory regulatory JJ cord-280571-ntgt5hy9 229 3 requirements requirement NNS cord-280571-ntgt5hy9 229 4 for for IN cord-280571-ntgt5hy9 229 5 ongoing ongoing JJ cord-280571-ntgt5hy9 229 6 quality quality NN cord-280571-ntgt5hy9 229 7 assurance assurance NN cord-280571-ntgt5hy9 229 8 monitoring monitoring NN cord-280571-ntgt5hy9 229 9 are be VBP cord-280571-ntgt5hy9 229 10 also also RB cord-280571-ntgt5hy9 229 11 fewer few JJR cord-280571-ntgt5hy9 229 12 for for IN cord-280571-ntgt5hy9 229 13 FDA FDA NNP cord-280571-ntgt5hy9 229 14 - - HYPH cord-280571-ntgt5hy9 229 15 approved approve VBN cord-280571-ntgt5hy9 229 16 / / SYM cord-280571-ntgt5hy9 229 17 cleared clear VBN cord-280571-ntgt5hy9 229 18 NAATs NAATs NNP cord-280571-ntgt5hy9 229 19 than than IN cord-280571-ntgt5hy9 229 20 for for IN cord-280571-ntgt5hy9 229 21 laboratory laboratory NN cord-280571-ntgt5hy9 229 22 - - HYPH cord-280571-ntgt5hy9 229 23 developed develop VBN cord-280571-ntgt5hy9 229 24 tests test NNS cord-280571-ntgt5hy9 229 25 [ [ -LRB- cord-280571-ntgt5hy9 229 26 42 42 CD cord-280571-ntgt5hy9 229 27 ] ] -RRB- cord-280571-ntgt5hy9 229 28 . . . cord-280571-ntgt5hy9 230 1 In in IN cord-280571-ntgt5hy9 230 2 addition addition NN cord-280571-ntgt5hy9 230 3 , , , cord-280571-ntgt5hy9 230 4 for for IN cord-280571-ntgt5hy9 230 5 regulatory regulatory JJ cord-280571-ntgt5hy9 230 6 reasons reason NNS cord-280571-ntgt5hy9 230 7 , , , cord-280571-ntgt5hy9 230 8 some some DT cord-280571-ntgt5hy9 230 9 health health NN cord-280571-ntgt5hy9 230 10 care care NN cord-280571-ntgt5hy9 230 11 institutions institution NNS cord-280571-ntgt5hy9 230 12 will will MD cord-280571-ntgt5hy9 230 13 only only RB cord-280571-ntgt5hy9 230 14 allow allow VB cord-280571-ntgt5hy9 230 15 the the DT cord-280571-ntgt5hy9 230 16 use use NN cord-280571-ntgt5hy9 230 17 of of IN cord-280571-ntgt5hy9 230 18 FDA FDA NNP cord-280571-ntgt5hy9 230 19 - - HYPH cord-280571-ntgt5hy9 230 20 approved approve VBN cord-280571-ntgt5hy9 230 21 / / SYM cord-280571-ntgt5hy9 230 22 cleared clear VBN cord-280571-ntgt5hy9 230 23 NAATs naat NNS cord-280571-ntgt5hy9 230 24 . . . cord-280571-ntgt5hy9 231 1 Because because IN cord-280571-ntgt5hy9 231 2 the the DT cord-280571-ntgt5hy9 231 3 clinical clinical JJ cord-280571-ntgt5hy9 231 4 relevance relevance NN cord-280571-ntgt5hy9 231 5 of of IN cord-280571-ntgt5hy9 231 6 the the DT cord-280571-ntgt5hy9 231 7 assays assay NNS cord-280571-ntgt5hy9 231 8 has have VBZ cord-280571-ntgt5hy9 231 9 been be VBN cord-280571-ntgt5hy9 231 10 established establish VBN cord-280571-ntgt5hy9 231 11 , , , cord-280571-ntgt5hy9 231 12 the the DT cord-280571-ntgt5hy9 231 13 use use NN cord-280571-ntgt5hy9 231 14 of of IN cord-280571-ntgt5hy9 231 15 FDA FDA NNP cord-280571-ntgt5hy9 231 16 - - HYPH cord-280571-ntgt5hy9 231 17 approved approve VBN cord-280571-ntgt5hy9 231 18 / / SYM cord-280571-ntgt5hy9 231 19 cleared clear VBN cord-280571-ntgt5hy9 231 20 NAATs NAATs NNP cord-280571-ntgt5hy9 231 21 has have VBZ cord-280571-ntgt5hy9 231 22 a a DT cord-280571-ntgt5hy9 231 23 higher high JJR cord-280571-ntgt5hy9 231 24 chance chance NN cord-280571-ntgt5hy9 231 25 of of IN cord-280571-ntgt5hy9 231 26 reimbursement reimbursement NN cord-280571-ntgt5hy9 231 27 from from IN cord-280571-ntgt5hy9 231 28 both both CC cord-280571-ntgt5hy9 231 29 federal federal JJ cord-280571-ntgt5hy9 231 30 and and CC cord-280571-ntgt5hy9 231 31 private private JJ cord-280571-ntgt5hy9 231 32 insurance insurance NN cord-280571-ntgt5hy9 231 33 payors payor NNS cord-280571-ntgt5hy9 231 34 . . . cord-280571-ntgt5hy9 232 1 However however RB cord-280571-ntgt5hy9 232 2 , , , cord-280571-ntgt5hy9 232 3 FDA FDA NNP cord-280571-ntgt5hy9 232 4 approval approval NN cord-280571-ntgt5hy9 232 5 / / SYM cord-280571-ntgt5hy9 232 6 clearance clearance NN cord-280571-ntgt5hy9 232 7 does do VBZ cord-280571-ntgt5hy9 232 8 not not RB cord-280571-ntgt5hy9 232 9 guarantee guarantee VB cord-280571-ntgt5hy9 232 10 that that IN cord-280571-ntgt5hy9 232 11 these these DT cord-280571-ntgt5hy9 232 12 tests test NNS cord-280571-ntgt5hy9 232 13 will will MD cord-280571-ntgt5hy9 232 14 be be VB cord-280571-ntgt5hy9 232 15 reimbursed reimburse VBN cord-280571-ntgt5hy9 232 16 , , , cord-280571-ntgt5hy9 232 17 and and CC cord-280571-ntgt5hy9 232 18 , , , cord-280571-ntgt5hy9 232 19 if if IN cord-280571-ntgt5hy9 232 20 reimbursed reimburse VBN cord-280571-ntgt5hy9 232 21 , , , cord-280571-ntgt5hy9 232 22 the the DT cord-280571-ntgt5hy9 232 23 actual actual JJ cord-280571-ntgt5hy9 232 24 amount amount NN cord-280571-ntgt5hy9 232 25 of of IN cord-280571-ntgt5hy9 232 26 the the DT cord-280571-ntgt5hy9 232 27 reimbursement reimbursement NN cord-280571-ntgt5hy9 232 28 can can MD cord-280571-ntgt5hy9 232 29 vary vary VB cord-280571-ntgt5hy9 232 30 from from IN cord-280571-ntgt5hy9 232 31 state state NN cord-280571-ntgt5hy9 232 32 to to IN cord-280571-ntgt5hy9 232 33 state state NN cord-280571-ntgt5hy9 232 34 and and CC cord-280571-ntgt5hy9 232 35 by by IN cord-280571-ntgt5hy9 232 36 payor payor NN cord-280571-ntgt5hy9 232 37 . . . cord-280571-ntgt5hy9 233 1 Finally finally RB cord-280571-ntgt5hy9 233 2 , , , cord-280571-ntgt5hy9 233 3 the the DT cord-280571-ntgt5hy9 233 4 simple simple JJ cord-280571-ntgt5hy9 233 5 - - HYPH cord-280571-ntgt5hy9 233 6 to to IN cord-280571-ntgt5hy9 233 7 - - HYPH cord-280571-ntgt5hy9 233 8 use use VB cord-280571-ntgt5hy9 233 9 fully fully RB cord-280571-ntgt5hy9 233 10 automated automate VBN cord-280571-ntgt5hy9 233 11 molecular molecular JJ cord-280571-ntgt5hy9 233 12 platforms platform NNS cord-280571-ntgt5hy9 233 13 , , , cord-280571-ntgt5hy9 233 14 such such JJ cord-280571-ntgt5hy9 233 15 as as IN cord-280571-ntgt5hy9 233 16 the the DT cord-280571-ntgt5hy9 233 17 GeneXpert GeneXpert NNP cord-280571-ntgt5hy9 233 18 and and CC cord-280571-ntgt5hy9 233 19 GeneSTAT GeneSTAT NNP cord-280571-ntgt5hy9 233 20 , , , cord-280571-ntgt5hy9 233 21 which which WDT cord-280571-ntgt5hy9 233 22 incorporate incorporate VBP cord-280571-ntgt5hy9 233 23 all all DT cord-280571-ntgt5hy9 233 24 steps step NNS cord-280571-ntgt5hy9 233 25 of of IN cord-280571-ntgt5hy9 233 26 the the DT cord-280571-ntgt5hy9 233 27 test test NN cord-280571-ntgt5hy9 233 28 process process NN cord-280571-ntgt5hy9 233 29 in in IN cord-280571-ntgt5hy9 233 30 a a DT cord-280571-ntgt5hy9 233 31 single single JJ cord-280571-ntgt5hy9 233 32 test test NN cord-280571-ntgt5hy9 233 33 cartridge cartridge NN cord-280571-ntgt5hy9 233 34 and and CC cord-280571-ntgt5hy9 233 35 have have VBP cord-280571-ntgt5hy9 233 36 random random JJ cord-280571-ntgt5hy9 233 37 - - HYPH cord-280571-ntgt5hy9 233 38 access access NN cord-280571-ntgt5hy9 233 39 sample sample NN cord-280571-ntgt5hy9 233 40 - - HYPH cord-280571-ntgt5hy9 233 41 in in RP cord-280571-ntgt5hy9 233 42 result result NN cord-280571-ntgt5hy9 233 43 - - HYPH cord-280571-ntgt5hy9 233 44 out out NN cord-280571-ntgt5hy9 233 45 reporting reporting NN cord-280571-ntgt5hy9 233 46 , , , cord-280571-ntgt5hy9 233 47 enable enable VB cord-280571-ntgt5hy9 233 48 laboratories laboratory NNS cord-280571-ntgt5hy9 233 49 of of IN cord-280571-ntgt5hy9 233 50 all all DT cord-280571-ntgt5hy9 233 51 sizes size NNS cord-280571-ntgt5hy9 233 52 to to TO cord-280571-ntgt5hy9 233 53 perform perform VB cord-280571-ntgt5hy9 233 54 rapid rapid JJ cord-280571-ntgt5hy9 233 55 , , , cord-280571-ntgt5hy9 233 56 accurate accurate JJ cord-280571-ntgt5hy9 233 57 , , , cord-280571-ntgt5hy9 233 58 and and CC cord-280571-ntgt5hy9 233 59 sensitive sensitive JJ cord-280571-ntgt5hy9 233 60 molecular molecular JJ cord-280571-ntgt5hy9 233 61 diagnostic diagnostic JJ cord-280571-ntgt5hy9 233 62 testing testing NN cord-280571-ntgt5hy9 233 63 . . . cord-280571-ntgt5hy9 234 1 The the DT cord-280571-ntgt5hy9 234 2 most most RBS cord-280571-ntgt5hy9 234 3 important important JJ cord-280571-ntgt5hy9 234 4 limitation limitation NN cord-280571-ntgt5hy9 234 5 of of IN cord-280571-ntgt5hy9 234 6 the the DT cord-280571-ntgt5hy9 234 7 current current JJ cord-280571-ntgt5hy9 234 8 FDA FDA NNP cord-280571-ntgt5hy9 234 9 - - HYPH cord-280571-ntgt5hy9 234 10 approved/ approved/ NNP cord-280571-ntgt5hy9 234 11 cleared clear VBD cord-280571-ntgt5hy9 235 1 NAATs NAATs NNP cord-280571-ntgt5hy9 235 2 is be VBZ cord-280571-ntgt5hy9 235 3 the the DT cord-280571-ntgt5hy9 235 4 lack lack NN cord-280571-ntgt5hy9 235 5 of of IN cord-280571-ntgt5hy9 235 6 tests test NNS cord-280571-ntgt5hy9 235 7 for for IN cord-280571-ntgt5hy9 235 8 the the DT cord-280571-ntgt5hy9 235 9 detection detection NN cord-280571-ntgt5hy9 235 10 of of IN cord-280571-ntgt5hy9 235 11 nonviral nonviral JJ cord-280571-ntgt5hy9 235 12 targets target NNS cord-280571-ntgt5hy9 235 13 . . . cord-280571-ntgt5hy9 236 1 In in IN cord-280571-ntgt5hy9 236 2 particular particular JJ cord-280571-ntgt5hy9 236 3 , , , cord-280571-ntgt5hy9 236 4 NAATs NAATs NNPS cord-280571-ntgt5hy9 236 5 are be VBP cord-280571-ntgt5hy9 236 6 needed need VBN cord-280571-ntgt5hy9 236 7 for for IN cord-280571-ntgt5hy9 236 8 the the DT cord-280571-ntgt5hy9 236 9 detection detection NN cord-280571-ntgt5hy9 236 10 of of IN cord-280571-ntgt5hy9 236 11 the the DT cord-280571-ntgt5hy9 236 12 atypical atypical JJ cord-280571-ntgt5hy9 236 13 pneumonia pneumonia NN cord-280571-ntgt5hy9 236 14 pathogens pathogen NNS cord-280571-ntgt5hy9 236 15 . . . cord-280571-ntgt5hy9 237 1 However however RB cord-280571-ntgt5hy9 237 2 , , , cord-280571-ntgt5hy9 237 3 the the DT cord-280571-ntgt5hy9 237 4 costs cost NNS cord-280571-ntgt5hy9 237 5 of of IN cord-280571-ntgt5hy9 237 6 clinical clinical JJ cord-280571-ntgt5hy9 237 7 trials trial NNS cord-280571-ntgt5hy9 237 8 for for IN cord-280571-ntgt5hy9 237 9 IVD IVD NNP cord-280571-ntgt5hy9 237 10 device device NN cord-280571-ntgt5hy9 237 11 clearance clearance NN cord-280571-ntgt5hy9 237 12 can can MD cord-280571-ntgt5hy9 237 13 sometimes sometimes RB cord-280571-ntgt5hy9 237 14 be be VB cord-280571-ntgt5hy9 237 15 quite quite RB cord-280571-ntgt5hy9 237 16 prohibitive prohibitive JJ cord-280571-ntgt5hy9 237 17 ( ( -LRB- cord-280571-ntgt5hy9 237 18 .$10 .$10 CD cord-280571-ntgt5hy9 237 19 million million CD cord-280571-ntgt5hy9 237 20 , , , cord-280571-ntgt5hy9 237 21 not not RB cord-280571-ntgt5hy9 237 22 including include VBG cord-280571-ntgt5hy9 237 23 the the DT cord-280571-ntgt5hy9 237 24 costs cost NNS cord-280571-ntgt5hy9 237 25 of of IN cord-280571-ntgt5hy9 237 26 developing develop VBG cord-280571-ntgt5hy9 237 27 and and CC cord-280571-ntgt5hy9 237 28 manufacturing manufacture VBG cord-280571-ntgt5hy9 237 29 the the DT cord-280571-ntgt5hy9 237 30 IVD IVD NNP cord-280571-ntgt5hy9 237 31 device device NN cord-280571-ntgt5hy9 237 32 ) ) -RRB- cord-280571-ntgt5hy9 237 33 and and CC cord-280571-ntgt5hy9 237 34 depend depend VB cord-280571-ntgt5hy9 237 35 on on IN cord-280571-ntgt5hy9 237 36 the the DT cord-280571-ntgt5hy9 237 37 complexity complexity NN cord-280571-ntgt5hy9 237 38 and and CC cord-280571-ntgt5hy9 237 39 clinical clinical JJ cord-280571-ntgt5hy9 237 40 relevance relevance NN cord-280571-ntgt5hy9 237 41 of of IN cord-280571-ntgt5hy9 237 42 the the DT cord-280571-ntgt5hy9 237 43 test test NN cord-280571-ntgt5hy9 237 44 and and CC cord-280571-ntgt5hy9 237 45 what what WP cord-280571-ntgt5hy9 237 46 is be VBZ cord-280571-ntgt5hy9 237 47 required require VBN cord-280571-ntgt5hy9 237 48 for for IN cord-280571-ntgt5hy9 237 49 FDA FDA NNP cord-280571-ntgt5hy9 237 50 approval approval NN cord-280571-ntgt5hy9 237 51 ( ( -LRB- cord-280571-ntgt5hy9 237 52 eg eg IN cord-280571-ntgt5hy9 237 53 , , , cord-280571-ntgt5hy9 237 54 number number NN cord-280571-ntgt5hy9 237 55 of of IN cord-280571-ntgt5hy9 237 56 trial trial NN cord-280571-ntgt5hy9 237 57 sites site NNS cord-280571-ntgt5hy9 237 58 , , , cord-280571-ntgt5hy9 237 59 number number NN cord-280571-ntgt5hy9 237 60 of of IN cord-280571-ntgt5hy9 237 61 patients patient NNS cord-280571-ntgt5hy9 237 62 enrolled enrol VBN cord-280571-ntgt5hy9 237 63 , , , cord-280571-ntgt5hy9 237 64 clinical clinical JJ cord-280571-ntgt5hy9 237 65 indications indication NNS cord-280571-ntgt5hy9 237 66 sought seek VBD cord-280571-ntgt5hy9 237 67 , , , cord-280571-ntgt5hy9 237 68 need need VBP cord-280571-ntgt5hy9 237 69 for for IN cord-280571-ntgt5hy9 237 70 long long JJ cord-280571-ntgt5hy9 237 71 - - HYPH cord-280571-ntgt5hy9 237 72 term term NN cord-280571-ntgt5hy9 237 73 patient patient JJ cord-280571-ntgt5hy9 237 74 follow follow NN cord-280571-ntgt5hy9 237 75 - - HYPH cord-280571-ntgt5hy9 237 76 up up NN cord-280571-ntgt5hy9 237 77 , , , cord-280571-ntgt5hy9 237 78 associated associate VBN cord-280571-ntgt5hy9 237 79 diagnostic diagnostic JJ cord-280571-ntgt5hy9 237 80 procedures procedure NNS cord-280571-ntgt5hy9 237 81 [ [ -LRB- cord-280571-ntgt5hy9 237 82 such such JJ cord-280571-ntgt5hy9 237 83 as as IN cord-280571-ntgt5hy9 237 84 biopsy biopsy NN cord-280571-ntgt5hy9 237 85 ] ] -RRB- cord-280571-ntgt5hy9 237 86 , , . cord-280571-ntgt5hy9 238 1 device device NN cord-280571-ntgt5hy9 238 2 evaluations evaluation NNS cord-280571-ntgt5hy9 238 3 , , , cord-280571-ntgt5hy9 238 4 predicate predicate NN cord-280571-ntgt5hy9 238 5 device device NN cord-280571-ntgt5hy9 238 6 comparisons comparison NNS cord-280571-ntgt5hy9 238 7 , , , cord-280571-ntgt5hy9 238 8 legal legal JJ cord-280571-ntgt5hy9 238 9 and and CC cord-280571-ntgt5hy9 238 10 regulatory regulatory JJ cord-280571-ntgt5hy9 238 11 components component NNS cord-280571-ntgt5hy9 238 12 , , , cord-280571-ntgt5hy9 238 13 and and CC cord-280571-ntgt5hy9 238 14 so so RB cord-280571-ntgt5hy9 238 15 forth forth RB cord-280571-ntgt5hy9 238 16 ) ) -RRB- cord-280571-ntgt5hy9 238 17 . . . cord-280571-ntgt5hy9 239 1 Manufacturers manufacturer NNS cord-280571-ntgt5hy9 239 2 must must MD cord-280571-ntgt5hy9 239 3 consider consider VB cord-280571-ntgt5hy9 239 4 the the DT cord-280571-ntgt5hy9 239 5 potential potential JJ cord-280571-ntgt5hy9 239 6 number number NN cord-280571-ntgt5hy9 239 7 of of IN cord-280571-ntgt5hy9 239 8 tests test NNS cord-280571-ntgt5hy9 239 9 that that WDT cord-280571-ntgt5hy9 239 10 will will MD cord-280571-ntgt5hy9 239 11 be be VB cord-280571-ntgt5hy9 239 12 purchased purchase VBN cord-280571-ntgt5hy9 239 13 and and CC cord-280571-ntgt5hy9 239 14 the the DT cord-280571-ntgt5hy9 239 15 difficulty difficulty NN cord-280571-ntgt5hy9 239 16 of of IN cord-280571-ntgt5hy9 239 17 the the DT cord-280571-ntgt5hy9 239 18 trials trial NNS cord-280571-ntgt5hy9 239 19 for for IN cord-280571-ntgt5hy9 239 20 low low JJ cord-280571-ntgt5hy9 239 21 - - HYPH cord-280571-ntgt5hy9 239 22 prevalence prevalence NN cord-280571-ntgt5hy9 239 23 pathogens pathogen NNS cord-280571-ntgt5hy9 239 24 before before IN cord-280571-ntgt5hy9 239 25 committing commit VBG cord-280571-ntgt5hy9 239 26 the the DT cord-280571-ntgt5hy9 239 27 finances finance NNS cord-280571-ntgt5hy9 239 28 and and CC cord-280571-ntgt5hy9 239 29 resources resource NNS cord-280571-ntgt5hy9 239 30 to to TO cord-280571-ntgt5hy9 239 31 bring bring VB cord-280571-ntgt5hy9 239 32 such such JJ cord-280571-ntgt5hy9 239 33 tests test NNS cord-280571-ntgt5hy9 239 34 through through IN cord-280571-ntgt5hy9 239 35 the the DT cord-280571-ntgt5hy9 239 36 approval approval NN cord-280571-ntgt5hy9 239 37 process process NN cord-280571-ntgt5hy9 239 38 . . . cord-280571-ntgt5hy9 240 1 These these DT cord-280571-ntgt5hy9 240 2 factors factor NNS cord-280571-ntgt5hy9 240 3 will will MD cord-280571-ntgt5hy9 240 4 continue continue VB cord-280571-ntgt5hy9 240 5 to to TO cord-280571-ntgt5hy9 240 6 limit limit VB cord-280571-ntgt5hy9 240 7 the the DT cord-280571-ntgt5hy9 240 8 scope scope NN cord-280571-ntgt5hy9 240 9 of of IN cord-280571-ntgt5hy9 240 10 FDA FDA NNP cord-280571-ntgt5hy9 240 11 - - HYPH cord-280571-ntgt5hy9 240 12 approved approve VBN cord-280571-ntgt5hy9 240 13 / / SYM cord-280571-ntgt5hy9 240 14 cleared clear VBN cord-280571-ntgt5hy9 240 15 NAATs NAATs NNP cord-280571-ntgt5hy9 240 16 until until IN cord-280571-ntgt5hy9 240 17 the the DT cord-280571-ntgt5hy9 240 18 approval approval NN cord-280571-ntgt5hy9 240 19 process process NN cord-280571-ntgt5hy9 240 20 can can MD cord-280571-ntgt5hy9 240 21 be be VB cord-280571-ntgt5hy9 240 22 modified modify VBN cord-280571-ntgt5hy9 240 23 to to TO cord-280571-ntgt5hy9 240 24 encourage encourage VB cord-280571-ntgt5hy9 240 25 the the DT cord-280571-ntgt5hy9 240 26 submission submission NN cord-280571-ntgt5hy9 240 27 of of IN cord-280571-ntgt5hy9 240 28 NAATs NAATs NNP cord-280571-ntgt5hy9 240 29 for for IN cord-280571-ntgt5hy9 240 30 low low JJ cord-280571-ntgt5hy9 240 31 - - HYPH cord-280571-ntgt5hy9 240 32 prevalence prevalence NN cord-280571-ntgt5hy9 240 33 targets target NNS cord-280571-ntgt5hy9 240 34 . . . cord-280571-ntgt5hy9 241 1 The the DT cord-280571-ntgt5hy9 241 2 current current JJ cord-280571-ntgt5hy9 241 3 formats format NNS cord-280571-ntgt5hy9 241 4 of of IN cord-280571-ntgt5hy9 241 5 the the DT cord-280571-ntgt5hy9 241 6 NAATs NAATs NNPS cord-280571-ntgt5hy9 241 7 require require VBP cord-280571-ntgt5hy9 241 8 laboratories laboratory NNS cord-280571-ntgt5hy9 241 9 to to TO cord-280571-ntgt5hy9 241 10 choose choose VB cord-280571-ntgt5hy9 241 11 between between IN cord-280571-ntgt5hy9 241 12 real real JJ cord-280571-ntgt5hy9 241 13 - - HYPH cord-280571-ntgt5hy9 241 14 time time NN cord-280571-ntgt5hy9 241 15 , , , cord-280571-ntgt5hy9 241 16 easier easy JJR cord-280571-ntgt5hy9 241 17 to to TO cord-280571-ntgt5hy9 241 18 perform perform VB cord-280571-ntgt5hy9 241 19 , , , cord-280571-ntgt5hy9 241 20 more more RBR cord-280571-ntgt5hy9 241 21 rapid rapid JJ cord-280571-ntgt5hy9 241 22 assays assay NNS cord-280571-ntgt5hy9 241 23 that that WDT cord-280571-ntgt5hy9 241 24 have have VBP cord-280571-ntgt5hy9 241 25 limited limit VBN cord-280571-ntgt5hy9 241 26 targets target NNS cord-280571-ntgt5hy9 241 27 ( ( -LRB- cord-280571-ntgt5hy9 241 28 generally generally RB cord-280571-ntgt5hy9 241 29 up up IN cord-280571-ntgt5hy9 241 30 to to IN cord-280571-ntgt5hy9 241 31 3 3 CD cord-280571-ntgt5hy9 241 32 ) ) -RRB- cord-280571-ntgt5hy9 241 33 and and CC cord-280571-ntgt5hy9 241 34 more more RBR cord-280571-ntgt5hy9 241 35 highly highly RB cord-280571-ntgt5hy9 241 36 multiplex multiplex JJ cord-280571-ntgt5hy9 241 37 tests test NNS cord-280571-ntgt5hy9 241 38 ( ( -LRB- cord-280571-ntgt5hy9 241 39 .10 .10 NFP cord-280571-ntgt5hy9 241 40 ) ) -RRB- cord-280571-ntgt5hy9 241 41 that that WDT cord-280571-ntgt5hy9 241 42 require require VBP cord-280571-ntgt5hy9 241 43 more more JJR cord-280571-ntgt5hy9 241 44 hands hand NNS cord-280571-ntgt5hy9 241 45 - - HYPH cord-280571-ntgt5hy9 241 46 on on RP cord-280571-ntgt5hy9 241 47 time time NN cord-280571-ntgt5hy9 241 48 and and CC cord-280571-ntgt5hy9 241 49 technical technical JJ cord-280571-ntgt5hy9 241 50 steps step NNS cord-280571-ntgt5hy9 241 51 and and CC cord-280571-ntgt5hy9 241 52 more more JJR cord-280571-ntgt5hy9 241 53 time time NN cord-280571-ntgt5hy9 241 54 to to TO cord-280571-ntgt5hy9 241 55 result result VB cord-280571-ntgt5hy9 241 56 reporting report VBG cord-280571-ntgt5hy9 241 57 . . . cord-280571-ntgt5hy9 242 1 NAATs NAATs NNP cord-280571-ntgt5hy9 242 2 with with IN cord-280571-ntgt5hy9 242 3 limited limited JJ cord-280571-ntgt5hy9 242 4 targets target NNS cord-280571-ntgt5hy9 242 5 would would MD cord-280571-ntgt5hy9 242 6 require require VB cord-280571-ntgt5hy9 242 7 laboratories laboratory NNS cord-280571-ntgt5hy9 242 8 to to TO cord-280571-ntgt5hy9 242 9 run run VB cord-280571-ntgt5hy9 242 10 multiple multiple JJ cord-280571-ntgt5hy9 242 11 tests test NNS cord-280571-ntgt5hy9 242 12 if if IN cord-280571-ntgt5hy9 242 13 a a DT cord-280571-ntgt5hy9 242 14 broader broad JJR cord-280571-ntgt5hy9 242 15 range range NN cord-280571-ntgt5hy9 242 16 of of IN cord-280571-ntgt5hy9 242 17 target target NN cord-280571-ntgt5hy9 242 18 detection detection NN cord-280571-ntgt5hy9 242 19 is be VBZ cord-280571-ntgt5hy9 242 20 indicated indicate VBN cord-280571-ntgt5hy9 242 21 . . . cord-280571-ntgt5hy9 243 1 Multiple multiple JJ cord-280571-ntgt5hy9 243 2 tests test NNS cord-280571-ntgt5hy9 243 3 would would MD cord-280571-ntgt5hy9 243 4 increase increase VB cord-280571-ntgt5hy9 243 5 both both CC cord-280571-ntgt5hy9 243 6 the the DT cord-280571-ntgt5hy9 243 7 required require VBN cord-280571-ntgt5hy9 243 8 technical technical JJ cord-280571-ntgt5hy9 243 9 time time NN cord-280571-ntgt5hy9 243 10 and and CC cord-280571-ntgt5hy9 243 11 the the DT cord-280571-ntgt5hy9 243 12 cost cost NN cord-280571-ntgt5hy9 243 13 per per IN cord-280571-ntgt5hy9 243 14 patient patient JJ cord-280571-ntgt5hy9 243 15 diagnosis diagnosis NN cord-280571-ntgt5hy9 243 16 . . . cord-280571-ntgt5hy9 244 1 Conversely conversely RB cord-280571-ntgt5hy9 244 2 , , , cord-280571-ntgt5hy9 244 3 the the DT cord-280571-ntgt5hy9 244 4 use use NN cord-280571-ntgt5hy9 244 5 of of IN cord-280571-ntgt5hy9 244 6 multiple multiple JJ cord-280571-ntgt5hy9 244 7 , , , cord-280571-ntgt5hy9 244 8 lower low JJR cord-280571-ntgt5hy9 244 9 multiplex multiplex NN cord-280571-ntgt5hy9 244 10 tests test NNS cord-280571-ntgt5hy9 244 11 allows allow VBZ cord-280571-ntgt5hy9 244 12 for for IN cord-280571-ntgt5hy9 244 13 the the DT cord-280571-ntgt5hy9 244 14 selection selection NN cord-280571-ntgt5hy9 244 15 of of IN cord-280571-ntgt5hy9 244 16 the the DT cord-280571-ntgt5hy9 244 17 most most RBS cord-280571-ntgt5hy9 244 18 appropriate appropriate JJ cord-280571-ntgt5hy9 244 19 panels panel NNS cord-280571-ntgt5hy9 244 20 as as IN cord-280571-ntgt5hy9 244 21 related relate VBN cord-280571-ntgt5hy9 244 22 to to IN cord-280571-ntgt5hy9 244 23 age age NN cord-280571-ntgt5hy9 244 24 of of IN cord-280571-ntgt5hy9 244 25 the the DT cord-280571-ntgt5hy9 244 26 patient patient NN cord-280571-ntgt5hy9 244 27 , , , cord-280571-ntgt5hy9 244 28 clinical clinical JJ cord-280571-ntgt5hy9 244 29 status status NN cord-280571-ntgt5hy9 244 30 , , , cord-280571-ntgt5hy9 244 31 underlying underlie VBG cord-280571-ntgt5hy9 244 32 disease disease NN cord-280571-ntgt5hy9 244 33 , , , cord-280571-ntgt5hy9 244 34 state state NN cord-280571-ntgt5hy9 244 35 of of IN cord-280571-ntgt5hy9 244 36 immune immune JJ cord-280571-ntgt5hy9 244 37 competence competence NN cord-280571-ntgt5hy9 244 38 , , , cord-280571-ntgt5hy9 244 39 and and CC cord-280571-ntgt5hy9 244 40 the the DT cord-280571-ntgt5hy9 244 41 suspected suspect VBN cord-280571-ntgt5hy9 244 42 virus(es virus(es CD cord-280571-ntgt5hy9 244 43 ) ) -RRB- cord-280571-ntgt5hy9 244 44 . . . cord-280571-ntgt5hy9 245 1 Currently currently RB cord-280571-ntgt5hy9 245 2 in in IN cord-280571-ntgt5hy9 245 3 development development NN cord-280571-ntgt5hy9 245 4 are be VBP cord-280571-ntgt5hy9 245 5 modified modify VBN cord-280571-ntgt5hy9 245 6 faster fast JJR cord-280571-ntgt5hy9 245 7 versions version NNS cord-280571-ntgt5hy9 245 8 of of IN cord-280571-ntgt5hy9 245 9 the the DT cord-280571-ntgt5hy9 245 10 highly highly RB cord-280571-ntgt5hy9 245 11 multiplex multiplex JJ cord-280571-ntgt5hy9 245 12 assays assay NNS cord-280571-ntgt5hy9 245 13 that that WDT cord-280571-ntgt5hy9 245 14 have have VBP cord-280571-ntgt5hy9 245 15 been be VBN cord-280571-ntgt5hy9 245 16 designed design VBN cord-280571-ntgt5hy9 245 17 to to TO cord-280571-ntgt5hy9 245 18 reduce reduce VB cord-280571-ntgt5hy9 245 19 technical technical JJ cord-280571-ntgt5hy9 245 20 hands hand NNS cord-280571-ntgt5hy9 245 21 - - HYPH cord-280571-ntgt5hy9 245 22 on on RP cord-280571-ntgt5hy9 245 23 time time NN cord-280571-ntgt5hy9 245 24 and and CC cord-280571-ntgt5hy9 245 25 the the DT cord-280571-ntgt5hy9 245 26 time time NN cord-280571-ntgt5hy9 245 27 to to TO cord-280571-ntgt5hy9 245 28 results result NNS cord-280571-ntgt5hy9 245 29 . . . cord-280571-ntgt5hy9 246 1 Some some DT cord-280571-ntgt5hy9 246 2 of of IN cord-280571-ntgt5hy9 246 3 the the DT cord-280571-ntgt5hy9 246 4 FDA FDA NNP cord-280571-ntgt5hy9 246 5 - - HYPH cord-280571-ntgt5hy9 246 6 approved approve VBN cord-280571-ntgt5hy9 246 7 / / SYM cord-280571-ntgt5hy9 246 8 cleared clear VBN cord-280571-ntgt5hy9 246 9 real real JJ cord-280571-ntgt5hy9 246 10 - - HYPH cord-280571-ntgt5hy9 246 11 time time NN cord-280571-ntgt5hy9 246 12 NAATs NAATs NNPS cord-280571-ntgt5hy9 246 13 do do VBP cord-280571-ntgt5hy9 246 14 not not RB cord-280571-ntgt5hy9 246 15 allow allow VB cord-280571-ntgt5hy9 246 16 the the DT cord-280571-ntgt5hy9 246 17 user user NN cord-280571-ntgt5hy9 246 18 to to TO cord-280571-ntgt5hy9 246 19 see see VB cord-280571-ntgt5hy9 246 20 and and CC cord-280571-ntgt5hy9 246 21 evaluate evaluate VB cord-280571-ntgt5hy9 246 22 the the DT cord-280571-ntgt5hy9 246 23 actual actual JJ cord-280571-ntgt5hy9 246 24 amplification amplification NN cord-280571-ntgt5hy9 246 25 curves curve NNS cord-280571-ntgt5hy9 246 26 . . . cord-280571-ntgt5hy9 247 1 The the DT cord-280571-ntgt5hy9 247 2 inability inability NN cord-280571-ntgt5hy9 247 3 to to TO cord-280571-ntgt5hy9 247 4 see see VB cord-280571-ntgt5hy9 247 5 the the DT cord-280571-ntgt5hy9 247 6 curves curve NNS cord-280571-ntgt5hy9 247 7 makes make VBZ cord-280571-ntgt5hy9 247 8 it -PRON- PRP cord-280571-ntgt5hy9 247 9 difficult difficult JJ cord-280571-ntgt5hy9 247 10 to to TO cord-280571-ntgt5hy9 247 11 troubleshoot troubleshoot VB cord-280571-ntgt5hy9 247 12 when when WRB cord-280571-ntgt5hy9 247 13 problems problem NNS cord-280571-ntgt5hy9 247 14 occur occur VBP cord-280571-ntgt5hy9 247 15 . . . cord-280571-ntgt5hy9 248 1 Although although IN cord-280571-ntgt5hy9 248 2 the the DT cord-280571-ntgt5hy9 248 3 user user NN cord-280571-ntgt5hy9 248 4 should should MD cord-280571-ntgt5hy9 248 5 not not RB cord-280571-ntgt5hy9 248 6 be be VB cord-280571-ntgt5hy9 248 7 able able JJ cord-280571-ntgt5hy9 248 8 to to TO cord-280571-ntgt5hy9 248 9 alter alter VB cord-280571-ntgt5hy9 248 10 cutoff cutoff NN cord-280571-ntgt5hy9 248 11 values value NNS cord-280571-ntgt5hy9 248 12 established establish VBN cord-280571-ntgt5hy9 248 13 during during IN cord-280571-ntgt5hy9 248 14 the the DT cord-280571-ntgt5hy9 248 15 FDA FDA NNP cord-280571-ntgt5hy9 248 16 trials trial NNS cord-280571-ntgt5hy9 248 17 , , , cord-280571-ntgt5hy9 248 18 access access NN cord-280571-ntgt5hy9 248 19 to to IN cord-280571-ntgt5hy9 248 20 all all DT cord-280571-ntgt5hy9 248 21 or or CC cord-280571-ntgt5hy9 248 22 part part NN cord-280571-ntgt5hy9 248 23 of of IN cord-280571-ntgt5hy9 248 24 the the DT cord-280571-ntgt5hy9 248 25 raw raw JJ cord-280571-ntgt5hy9 248 26 data data NN cord-280571-ntgt5hy9 248 27 is be VBZ cord-280571-ntgt5hy9 248 28 desirable desirable JJ cord-280571-ntgt5hy9 248 29 . . . cord-280571-ntgt5hy9 249 1 One one CD cord-280571-ntgt5hy9 249 2 caveat caveat NN cord-280571-ntgt5hy9 249 3 for for IN cord-280571-ntgt5hy9 249 4 most most JJS cord-280571-ntgt5hy9 249 5 qualitative qualitative JJ cord-280571-ntgt5hy9 249 6 NAATs NAATs NNPS cord-280571-ntgt5hy9 249 7 is be VBZ cord-280571-ntgt5hy9 249 8 that that IN cord-280571-ntgt5hy9 249 9 they -PRON- PRP cord-280571-ntgt5hy9 249 10 can can MD cord-280571-ntgt5hy9 249 11 not not RB cord-280571-ntgt5hy9 249 12 distinguish distinguish VB cord-280571-ntgt5hy9 249 13 between between IN cord-280571-ntgt5hy9 249 14 live live JJ cord-280571-ntgt5hy9 249 15 and and CC cord-280571-ntgt5hy9 249 16 dead dead JJ cord-280571-ntgt5hy9 249 17 organisms organism NNS cord-280571-ntgt5hy9 249 18 and and CC cord-280571-ntgt5hy9 249 19 therefore therefore RB cord-280571-ntgt5hy9 249 20 , , , cord-280571-ntgt5hy9 249 21 depending depend VBG cord-280571-ntgt5hy9 249 22 on on IN cord-280571-ntgt5hy9 249 23 the the DT cord-280571-ntgt5hy9 249 24 time time NN cord-280571-ntgt5hy9 249 25 for for IN cord-280571-ntgt5hy9 249 26 nucleic nucleic JJ cord-280571-ntgt5hy9 249 27 acid acid NN cord-280571-ntgt5hy9 249 28 clearance clearance NN cord-280571-ntgt5hy9 249 29 , , , cord-280571-ntgt5hy9 249 30 can can MD cord-280571-ntgt5hy9 249 31 be be VB cord-280571-ntgt5hy9 249 32 limited limit VBN cord-280571-ntgt5hy9 249 33 in in IN cord-280571-ntgt5hy9 249 34 monitoring monitor VBG cord-280571-ntgt5hy9 249 35 response response NN cord-280571-ntgt5hy9 249 36 to to IN cord-280571-ntgt5hy9 249 37 therapy therapy NN cord-280571-ntgt5hy9 249 38 . . . cord-280571-ntgt5hy9 250 1 In in IN cord-280571-ntgt5hy9 250 2 addition addition NN cord-280571-ntgt5hy9 250 3 , , , cord-280571-ntgt5hy9 250 4 with with IN cord-280571-ntgt5hy9 250 5 multiple multiple JJ cord-280571-ntgt5hy9 250 6 viral viral JJ cord-280571-ntgt5hy9 250 7 infections infection NNS cord-280571-ntgt5hy9 250 8 , , , cord-280571-ntgt5hy9 250 9 determining determine VBG cord-280571-ntgt5hy9 250 10 the the DT cord-280571-ntgt5hy9 250 11 relevance relevance NN cord-280571-ntgt5hy9 250 12 of of IN cord-280571-ntgt5hy9 250 13 each each DT cord-280571-ntgt5hy9 250 14 virus virus NN cord-280571-ntgt5hy9 250 15 present present JJ cord-280571-ntgt5hy9 250 16 in in IN cord-280571-ntgt5hy9 250 17 the the DT cord-280571-ntgt5hy9 250 18 sample sample NN cord-280571-ntgt5hy9 250 19 is be VBZ cord-280571-ntgt5hy9 250 20 difficult difficult JJ cord-280571-ntgt5hy9 250 21 , , , cord-280571-ntgt5hy9 250 22 because because IN cord-280571-ntgt5hy9 250 23 residual residual JJ cord-280571-ntgt5hy9 250 24 virus virus NN cord-280571-ntgt5hy9 250 25 detected detect VBN cord-280571-ntgt5hy9 250 26 may may MD cord-280571-ntgt5hy9 250 27 have have VB cord-280571-ntgt5hy9 250 28 been be VBN cord-280571-ntgt5hy9 250 29 from from IN cord-280571-ntgt5hy9 250 30 a a DT cord-280571-ntgt5hy9 250 31 previous previous JJ cord-280571-ntgt5hy9 250 32 infection infection NN cord-280571-ntgt5hy9 250 33 and and CC cord-280571-ntgt5hy9 250 34 may may MD cord-280571-ntgt5hy9 250 35 not not RB cord-280571-ntgt5hy9 250 36 be be VB cord-280571-ntgt5hy9 250 37 contributing contribute VBG cord-280571-ntgt5hy9 250 38 to to IN cord-280571-ntgt5hy9 250 39 the the DT cord-280571-ntgt5hy9 250 40 current current JJ cord-280571-ntgt5hy9 250 41 illness illness NN cord-280571-ntgt5hy9 250 42 . . . cord-280571-ntgt5hy9 251 1 The the DT cord-280571-ntgt5hy9 251 2 development development NN cord-280571-ntgt5hy9 251 3 of of IN cord-280571-ntgt5hy9 251 4 quantitative quantitative JJ cord-280571-ntgt5hy9 251 5 assays assay NNS cord-280571-ntgt5hy9 251 6 and and CC cord-280571-ntgt5hy9 251 7 evidence evidence NN cord-280571-ntgt5hy9 251 8 of of IN cord-280571-ntgt5hy9 251 9 declining decline VBG cord-280571-ntgt5hy9 251 10 viral viral JJ cord-280571-ntgt5hy9 251 11 load load NN cord-280571-ntgt5hy9 251 12 may may MD cord-280571-ntgt5hy9 251 13 clarify clarify VB cord-280571-ntgt5hy9 251 14 or or CC cord-280571-ntgt5hy9 251 15 resolve resolve VB cord-280571-ntgt5hy9 251 16 both both DT cord-280571-ntgt5hy9 251 17 of of IN cord-280571-ntgt5hy9 251 18 these these DT cord-280571-ntgt5hy9 251 19 issues issue NNS cord-280571-ntgt5hy9 251 20 . . . cord-280571-ntgt5hy9 252 1 Finally finally RB cord-280571-ntgt5hy9 252 2 , , , cord-280571-ntgt5hy9 252 3 issues issue NNS cord-280571-ntgt5hy9 252 4 relating relate VBG cord-280571-ntgt5hy9 252 5 to to IN cord-280571-ntgt5hy9 252 6 billing billing NN cord-280571-ntgt5hy9 252 7 and and CC cord-280571-ntgt5hy9 252 8 reimbursement reimbursement NN cord-280571-ntgt5hy9 252 9 are be VBP cord-280571-ntgt5hy9 252 10 substantial substantial JJ cord-280571-ntgt5hy9 252 11 . . . cord-280571-ntgt5hy9 253 1 The the DT cord-280571-ntgt5hy9 253 2 lack lack NN cord-280571-ntgt5hy9 253 3 of of IN cord-280571-ntgt5hy9 253 4 specific specific JJ cord-280571-ntgt5hy9 253 5 Current current JJ cord-280571-ntgt5hy9 253 6 Procedural procedural JJ cord-280571-ntgt5hy9 253 7 Terminology terminology NN cord-280571-ntgt5hy9 253 8 ( ( -LRB- cord-280571-ntgt5hy9 253 9 CPT CPT NNP cord-280571-ntgt5hy9 253 10 ) ) -RRB- cord-280571-ntgt5hy9 253 11 codes code NNS cord-280571-ntgt5hy9 253 12 for for IN cord-280571-ntgt5hy9 253 13 each each DT cord-280571-ntgt5hy9 253 14 of of IN cord-280571-ntgt5hy9 253 15 the the DT cord-280571-ntgt5hy9 253 16 individual individual JJ cord-280571-ntgt5hy9 253 17 targets target NNS cord-280571-ntgt5hy9 253 18 requires require VBZ cord-280571-ntgt5hy9 253 19 laboratories laboratory NNS cord-280571-ntgt5hy9 253 20 to to IN cord-280571-ntgt5hy9 253 21 bill bill VB cord-280571-ntgt5hy9 253 22 for for IN cord-280571-ntgt5hy9 253 23 multiple multiple JJ cord-280571-ntgt5hy9 253 24 targets target NNS cord-280571-ntgt5hy9 253 25 using use VBG cord-280571-ntgt5hy9 253 26 the the DT cord-280571-ntgt5hy9 253 27 same same JJ cord-280571-ntgt5hy9 253 28 generic generic JJ cord-280571-ntgt5hy9 253 29 amplified amplify VBN cord-280571-ntgt5hy9 253 30 probe probe NN cord-280571-ntgt5hy9 253 31 CPT CPT NNP cord-280571-ntgt5hy9 253 32 code code NN cord-280571-ntgt5hy9 253 33 ( ( -LRB- cord-280571-ntgt5hy9 253 34 87798 87798 CD cord-280571-ntgt5hy9 253 35 ) ) -RRB- cord-280571-ntgt5hy9 253 36 . . . cord-280571-ntgt5hy9 254 1 Although although IN cord-280571-ntgt5hy9 254 2 it -PRON- PRP cord-280571-ntgt5hy9 254 3 is be VBZ cord-280571-ntgt5hy9 254 4 appropriate appropriate JJ cord-280571-ntgt5hy9 254 5 to to IN cord-280571-ntgt5hy9 254 6 bill bill VB cord-280571-ntgt5hy9 254 7 for for IN cord-280571-ntgt5hy9 254 8 each each DT cord-280571-ntgt5hy9 254 9 target target NN cord-280571-ntgt5hy9 254 10 present present JJ cord-280571-ntgt5hy9 254 11 in in IN cord-280571-ntgt5hy9 254 12 a a DT cord-280571-ntgt5hy9 254 13 multiplex multiplex JJ cord-280571-ntgt5hy9 254 14 assay assay NN cord-280571-ntgt5hy9 254 15 , , , cord-280571-ntgt5hy9 254 16 the the DT cord-280571-ntgt5hy9 254 17 use use NN cord-280571-ntgt5hy9 254 18 of of IN cord-280571-ntgt5hy9 254 19 the the DT cord-280571-ntgt5hy9 254 20 same same JJ cord-280571-ntgt5hy9 254 21 CPT CPT NNP cord-280571-ntgt5hy9 254 22 code code NN cord-280571-ntgt5hy9 254 23 multiple multiple JJ cord-280571-ntgt5hy9 254 24 times time NNS cord-280571-ntgt5hy9 254 25 for for IN cord-280571-ntgt5hy9 254 26 a a DT cord-280571-ntgt5hy9 254 27 single single JJ cord-280571-ntgt5hy9 254 28 test test NN cord-280571-ntgt5hy9 254 29 can can MD cord-280571-ntgt5hy9 254 30 be be VB cord-280571-ntgt5hy9 254 31 problematic problematic JJ cord-280571-ntgt5hy9 254 32 . . . cord-280571-ntgt5hy9 255 1 For for IN cord-280571-ntgt5hy9 255 2 example example NN cord-280571-ntgt5hy9 255 3 , , , cord-280571-ntgt5hy9 255 4 many many JJ cord-280571-ntgt5hy9 255 5 laboratory laboratory NN cord-280571-ntgt5hy9 255 6 or or CC cord-280571-ntgt5hy9 255 7 hospital hospital NN cord-280571-ntgt5hy9 255 8 billing billing NN cord-280571-ntgt5hy9 255 9 systems system NNS cord-280571-ntgt5hy9 255 10 do do VBP cord-280571-ntgt5hy9 255 11 not not RB cord-280571-ntgt5hy9 255 12 recognize recognize VB cord-280571-ntgt5hy9 255 13 multiple multiple JJ cord-280571-ntgt5hy9 255 14 similar similar JJ cord-280571-ntgt5hy9 255 15 CPTs cpt NNS cord-280571-ntgt5hy9 255 16 for for IN cord-280571-ntgt5hy9 255 17 a a DT cord-280571-ntgt5hy9 255 18 single single JJ cord-280571-ntgt5hy9 255 19 test test NN cord-280571-ntgt5hy9 255 20 and and CC cord-280571-ntgt5hy9 255 21 will will MD cord-280571-ntgt5hy9 255 22 only only RB cord-280571-ntgt5hy9 255 23 drop drop VB cord-280571-ntgt5hy9 255 24 1 1 CD cord-280571-ntgt5hy9 255 25 CPT CPT NNP cord-280571-ntgt5hy9 255 26 code code NN cord-280571-ntgt5hy9 255 27 charge charge NN cord-280571-ntgt5hy9 255 28 . . . cord-280571-ntgt5hy9 256 1 Some some DT cord-280571-ntgt5hy9 256 2 insurance insurance NN cord-280571-ntgt5hy9 256 3 payors payor NNS cord-280571-ntgt5hy9 256 4 will will MD cord-280571-ntgt5hy9 256 5 cover cover VB cord-280571-ntgt5hy9 256 6 only only RB cord-280571-ntgt5hy9 256 7 the the DT cord-280571-ntgt5hy9 256 8 charge charge NN cord-280571-ntgt5hy9 256 9 of of IN cord-280571-ntgt5hy9 256 10 the the DT cord-280571-ntgt5hy9 256 11 first first JJ cord-280571-ntgt5hy9 256 12 CPT CPT NNP cord-280571-ntgt5hy9 256 13 code code NN cord-280571-ntgt5hy9 256 14 , , , cord-280571-ntgt5hy9 256 15 and and CC cord-280571-ntgt5hy9 256 16 there there EX cord-280571-ntgt5hy9 256 17 are be VBP cord-280571-ntgt5hy9 256 18 also also RB cord-280571-ntgt5hy9 256 19 limitations limitation NNS cord-280571-ntgt5hy9 256 20 on on IN cord-280571-ntgt5hy9 256 21 how how WRB cord-280571-ntgt5hy9 256 22 many many JJ cord-280571-ntgt5hy9 256 23 times time NNS cord-280571-ntgt5hy9 256 24 per per IN cord-280571-ntgt5hy9 256 25 day day NN cord-280571-ntgt5hy9 256 26 a a DT cord-280571-ntgt5hy9 256 27 similar similar JJ cord-280571-ntgt5hy9 256 28 CPT CPT NNP cord-280571-ntgt5hy9 256 29 code code NN cord-280571-ntgt5hy9 256 30 can can MD cord-280571-ntgt5hy9 256 31 be be VB cord-280571-ntgt5hy9 256 32 billed bill VBN cord-280571-ntgt5hy9 256 33 . . . cord-280571-ntgt5hy9 257 1 As as IN cord-280571-ntgt5hy9 257 2 a a DT cord-280571-ntgt5hy9 257 3 result result NN cord-280571-ntgt5hy9 257 4 , , , cord-280571-ntgt5hy9 257 5 reimbursement reimbursement NN cord-280571-ntgt5hy9 257 6 for for IN cord-280571-ntgt5hy9 257 7 a a DT cord-280571-ntgt5hy9 257 8 highly highly RB cord-280571-ntgt5hy9 257 9 multiplexed multiplexed JJ cord-280571-ntgt5hy9 257 10 assay assay NN cord-280571-ntgt5hy9 257 11 could could MD cord-280571-ntgt5hy9 257 12 be be VB cord-280571-ntgt5hy9 257 13 limited limit VBN cord-280571-ntgt5hy9 257 14 to to IN cord-280571-ntgt5hy9 257 15 1 1 CD cord-280571-ntgt5hy9 257 16 charge charge NN cord-280571-ntgt5hy9 257 17 , , , cord-280571-ntgt5hy9 257 18 thereby thereby RB cord-280571-ntgt5hy9 257 19 significantly significantly RB cord-280571-ntgt5hy9 257 20 increasing increase VBG cord-280571-ntgt5hy9 257 21 the the DT cord-280571-ntgt5hy9 257 22 costs cost NNS cord-280571-ntgt5hy9 257 23 to to IN cord-280571-ntgt5hy9 257 24 the the DT cord-280571-ntgt5hy9 257 25 laboratory laboratory NN cord-280571-ntgt5hy9 257 26 and and CC cord-280571-ntgt5hy9 257 27 decreasing decrease VBG cord-280571-ntgt5hy9 257 28 test test NN cord-280571-ntgt5hy9 257 29 profitability profitability NN cord-280571-ntgt5hy9 257 30 . . . cord-280571-ntgt5hy9 258 1 Under under IN cord-280571-ntgt5hy9 258 2 these these DT cord-280571-ntgt5hy9 258 3 circumstances circumstance NNS cord-280571-ntgt5hy9 258 4 and and CC cord-280571-ntgt5hy9 258 5 with with IN cord-280571-ntgt5hy9 258 6 pressure pressure NN cord-280571-ntgt5hy9 258 7 to to TO cord-280571-ntgt5hy9 258 8 reduce reduce VB cord-280571-ntgt5hy9 258 9 medical medical JJ cord-280571-ntgt5hy9 258 10 costs cost NNS cord-280571-ntgt5hy9 258 11 , , , cord-280571-ntgt5hy9 258 12 many many JJ cord-280571-ntgt5hy9 258 13 administrators administrator NNS cord-280571-ntgt5hy9 258 14 will will MD cord-280571-ntgt5hy9 258 15 not not RB cord-280571-ntgt5hy9 258 16 approve approve VB cord-280571-ntgt5hy9 258 17 the the DT cord-280571-ntgt5hy9 258 18 implementation implementation NN cord-280571-ntgt5hy9 258 19 of of IN cord-280571-ntgt5hy9 258 20 this this DT cord-280571-ntgt5hy9 258 21 testing testing NN cord-280571-ntgt5hy9 258 22 if if IN cord-280571-ntgt5hy9 258 23 reimbursement reimbursement NN cord-280571-ntgt5hy9 258 24 is be VBZ cord-280571-ntgt5hy9 258 25 questionable questionable JJ cord-280571-ntgt5hy9 258 26 . . . cord-280571-ntgt5hy9 259 1 Laboratories laboratory NNS cord-280571-ntgt5hy9 259 2 need need VBP cord-280571-ntgt5hy9 259 3 analyte analyte VBN cord-280571-ntgt5hy9 259 4 - - HYPH cord-280571-ntgt5hy9 259 5 specific specific JJ cord-280571-ntgt5hy9 259 6 CPT CPT NNP cord-280571-ntgt5hy9 259 7 codes code NNS cord-280571-ntgt5hy9 259 8 , , , cord-280571-ntgt5hy9 259 9 and and CC cord-280571-ntgt5hy9 259 10 payors payor NNS cord-280571-ntgt5hy9 259 11 should should MD cord-280571-ntgt5hy9 259 12 reimburse reimburse VB cord-280571-ntgt5hy9 259 13 for for IN cord-280571-ntgt5hy9 259 14 medically medically RB cord-280571-ntgt5hy9 259 15 relevant relevant JJ cord-280571-ntgt5hy9 259 16 NAATs naat NNS cord-280571-ntgt5hy9 259 17 . . . cord-280571-ntgt5hy9 260 1 The the DT cord-280571-ntgt5hy9 260 2 North North NNP cord-280571-ntgt5hy9 260 3 Shore Shore NNP cord-280571-ntgt5hy9 260 4 - - HYPH cord-280571-ntgt5hy9 260 5 Long Long NNP cord-280571-ntgt5hy9 260 6 Island Island NNP cord-280571-ntgt5hy9 260 7 Jewish Jewish NNP cord-280571-ntgt5hy9 260 8 Health Health NNP cord-280571-ntgt5hy9 260 9 System System NNP cord-280571-ntgt5hy9 260 10 ( ( -LRB- cord-280571-ntgt5hy9 260 11 NS NS NNP cord-280571-ntgt5hy9 260 12 - - HYPH cord-280571-ntgt5hy9 260 13 LIJHS LIJHS NNP cord-280571-ntgt5hy9 260 14 ) ) -RRB- cord-280571-ntgt5hy9 261 1 Infectious Infectious NNP cord-280571-ntgt5hy9 261 2 Diseases Diseases NNPS cord-280571-ntgt5hy9 261 3 Molecular Molecular NNP cord-280571-ntgt5hy9 261 4 Diagnostics Diagnostics NNPS cord-280571-ntgt5hy9 261 5 Laboratory Laboratory NNP cord-280571-ntgt5hy9 261 6 opened open VBD cord-280571-ntgt5hy9 261 7 12 12 CD cord-280571-ntgt5hy9 261 8 years year NNS cord-280571-ntgt5hy9 261 9 ago ago RB cord-280571-ntgt5hy9 261 10 . . . cord-280571-ntgt5hy9 262 1 We -PRON- PRP cord-280571-ntgt5hy9 262 2 performed perform VBD cord-280571-ntgt5hy9 262 3 3 3 CD cord-280571-ntgt5hy9 262 4 tests test NNS cord-280571-ntgt5hy9 262 5 : : : cord-280571-ntgt5hy9 262 6 human human JJ cord-280571-ntgt5hy9 262 7 immunodeficiency immunodeficiency NN cord-280571-ntgt5hy9 262 8 virus virus NN cord-280571-ntgt5hy9 262 9 type type NN cord-280571-ntgt5hy9 262 10 1 1 CD cord-280571-ntgt5hy9 262 11 viral viral JJ cord-280571-ntgt5hy9 262 12 load load NN cord-280571-ntgt5hy9 262 13 , , , cord-280571-ntgt5hy9 262 14 AMTD AMTD NNP cord-280571-ntgt5hy9 262 15 , , , cord-280571-ntgt5hy9 262 16 and and CC cord-280571-ntgt5hy9 262 17 Chlamydia Chlamydia NNP cord-280571-ntgt5hy9 262 18 trachomatis/ trachomatis/ ADD cord-280571-ntgt5hy9 263 1 Neisseria Neisseria NNP cord-280571-ntgt5hy9 263 2 gonorrhoeae gonorrhoeae NNP cord-280571-ntgt5hy9 263 3 NAATs NAATs NNP cord-280571-ntgt5hy9 263 4 , , , cord-280571-ntgt5hy9 263 5 with with IN cord-280571-ntgt5hy9 263 6 a a DT cord-280571-ntgt5hy9 263 7 total total JJ cord-280571-ntgt5hy9 263 8 testing testing NN cord-280571-ntgt5hy9 263 9 volume volume NN cord-280571-ntgt5hy9 263 10 of of IN cord-280571-ntgt5hy9 263 11 5000 5000 CD cord-280571-ntgt5hy9 263 12 tests test NNS cord-280571-ntgt5hy9 263 13 per per IN cord-280571-ntgt5hy9 263 14 year year NN cord-280571-ntgt5hy9 263 15 . . . cord-280571-ntgt5hy9 264 1 Today today NN cord-280571-ntgt5hy9 264 2 , , , cord-280571-ntgt5hy9 264 3 the the DT cord-280571-ntgt5hy9 264 4 laboratory laboratory NN cord-280571-ntgt5hy9 264 5 performs perform VBZ cord-280571-ntgt5hy9 264 6 NAATs NAATs NNP cord-280571-ntgt5hy9 264 7 for for IN cord-280571-ntgt5hy9 264 8 40 40 CD cord-280571-ntgt5hy9 264 9 different different JJ cord-280571-ntgt5hy9 264 10 pathogens pathogen NNS cord-280571-ntgt5hy9 264 11 ( ( -LRB- cord-280571-ntgt5hy9 264 12 including include VBG cord-280571-ntgt5hy9 264 13 bacterial bacterial JJ cord-280571-ntgt5hy9 264 14 , , , cord-280571-ntgt5hy9 264 15 mycobacterial mycobacterial JJ cord-280571-ntgt5hy9 264 16 , , , cord-280571-ntgt5hy9 264 17 fungal fungal JJ cord-280571-ntgt5hy9 264 18 , , , cord-280571-ntgt5hy9 264 19 parasitic parasitic JJ cord-280571-ntgt5hy9 264 20 , , , cord-280571-ntgt5hy9 264 21 and and CC cord-280571-ntgt5hy9 264 22 viral viral JJ cord-280571-ntgt5hy9 264 23 targets target NNS cord-280571-ntgt5hy9 264 24 ) ) -RRB- cord-280571-ntgt5hy9 264 25 , , , cord-280571-ntgt5hy9 264 26 with with IN cord-280571-ntgt5hy9 264 27 a a DT cord-280571-ntgt5hy9 264 28 volume volume NN cord-280571-ntgt5hy9 264 29 of of IN cord-280571-ntgt5hy9 264 30 more more JJR cord-280571-ntgt5hy9 264 31 than than IN cord-280571-ntgt5hy9 264 32 225,000 225,000 CD cord-280571-ntgt5hy9 264 33 tests test NNS cord-280571-ntgt5hy9 264 34 per per IN cord-280571-ntgt5hy9 264 35 year year NN cord-280571-ntgt5hy9 264 36 , , , cord-280571-ntgt5hy9 264 37 and and CC cord-280571-ntgt5hy9 264 38 in in IN cord-280571-ntgt5hy9 264 39 space space NN cord-280571-ntgt5hy9 264 40 that that WDT cord-280571-ntgt5hy9 264 41 has have VBZ cord-280571-ntgt5hy9 264 42 tripled triple VBN cord-280571-ntgt5hy9 264 43 in in IN cord-280571-ntgt5hy9 264 44 size size NN cord-280571-ntgt5hy9 264 45 . . . cord-280571-ntgt5hy9 265 1 Molecular molecular JJ cord-280571-ntgt5hy9 265 2 diagnostics diagnostic NNS cord-280571-ntgt5hy9 265 3 for for IN cord-280571-ntgt5hy9 265 4 infectious infectious JJ cord-280571-ntgt5hy9 265 5 diseases disease NNS cord-280571-ntgt5hy9 265 6 , , , cord-280571-ntgt5hy9 265 7 along along IN cord-280571-ntgt5hy9 265 8 with with IN cord-280571-ntgt5hy9 265 9 molecular molecular JJ cord-280571-ntgt5hy9 265 10 pathology pathology NN cord-280571-ntgt5hy9 265 11 , , , cord-280571-ntgt5hy9 265 12 are be VBP cord-280571-ntgt5hy9 265 13 2 2 CD cord-280571-ntgt5hy9 265 14 of of IN cord-280571-ntgt5hy9 265 15 the the DT cord-280571-ntgt5hy9 265 16 fastest fast JJS cord-280571-ntgt5hy9 265 17 growing grow VBG cord-280571-ntgt5hy9 265 18 laboratory laboratory NN cord-280571-ntgt5hy9 265 19 departments department NNS cord-280571-ntgt5hy9 265 20 in in IN cord-280571-ntgt5hy9 265 21 the the DT cord-280571-ntgt5hy9 265 22 NS NS NNP cord-280571-ntgt5hy9 265 23 - - HYPH cord-280571-ntgt5hy9 265 24 LIJHS LIJHS NNP cord-280571-ntgt5hy9 265 25 . . . cord-280571-ntgt5hy9 266 1 In in IN cord-280571-ntgt5hy9 266 2 addition addition NN cord-280571-ntgt5hy9 266 3 , , , cord-280571-ntgt5hy9 266 4 as as IN cord-280571-ntgt5hy9 266 5 best good JJS cord-280571-ntgt5hy9 266 6 exemplified exemplify VBN cord-280571-ntgt5hy9 266 7 by by IN cord-280571-ntgt5hy9 266 8 the the DT cord-280571-ntgt5hy9 266 9 2001 2001 CD cord-280571-ntgt5hy9 266 10 anthrax anthrax NN cord-280571-ntgt5hy9 266 11 bioterrorism bioterrorism NN cord-280571-ntgt5hy9 266 12 event event NN cord-280571-ntgt5hy9 266 13 and and CC cord-280571-ntgt5hy9 266 14 the the DT cord-280571-ntgt5hy9 266 15 2009 2009 CD cord-280571-ntgt5hy9 266 16 influenza influenza NN cord-280571-ntgt5hy9 266 17 A a DT cord-280571-ntgt5hy9 266 18 H1N1 H1N1 NNP cord-280571-ntgt5hy9 266 19 pandemic pandemic NN cord-280571-ntgt5hy9 266 20 , , , cord-280571-ntgt5hy9 266 21 laboratories laboratory NNS cord-280571-ntgt5hy9 266 22 must must MD cord-280571-ntgt5hy9 266 23 be be VB cord-280571-ntgt5hy9 266 24 able able JJ cord-280571-ntgt5hy9 266 25 to to TO cord-280571-ntgt5hy9 266 26 respond respond VB cord-280571-ntgt5hy9 266 27 immediately immediately RB cord-280571-ntgt5hy9 266 28 by by IN cord-280571-ntgt5hy9 266 29 rapidly rapidly RB cord-280571-ntgt5hy9 266 30 expanding expand VBG cord-280571-ntgt5hy9 266 31 testing testing NN cord-280571-ntgt5hy9 266 32 capabilities capability NNS cord-280571-ntgt5hy9 266 33 , , , cord-280571-ntgt5hy9 266 34 including include VBG cord-280571-ntgt5hy9 266 35 sensitive sensitive JJ cord-280571-ntgt5hy9 266 36 and and CC cord-280571-ntgt5hy9 266 37 specific specific JJ cord-280571-ntgt5hy9 266 38 molecular molecular JJ cord-280571-ntgt5hy9 266 39 diagnostics diagnostic NNS cord-280571-ntgt5hy9 266 40 [ [ -LRB- cord-280571-ntgt5hy9 266 41 43 43 CD cord-280571-ntgt5hy9 266 42 ] ] -RRB- cord-280571-ntgt5hy9 266 43 . . . cord-280571-ntgt5hy9 267 1 At at IN cord-280571-ntgt5hy9 267 2 the the DT cord-280571-ntgt5hy9 267 3 onset onset NN cord-280571-ntgt5hy9 267 4 of of IN cord-280571-ntgt5hy9 267 5 the the DT cord-280571-ntgt5hy9 267 6 Queens Queens NNPS cord-280571-ntgt5hy9 267 7 , , , cord-280571-ntgt5hy9 267 8 New New NNP cord-280571-ntgt5hy9 267 9 York York NNP cord-280571-ntgt5hy9 267 10 , , , cord-280571-ntgt5hy9 267 11 area area NN cord-280571-ntgt5hy9 267 12 2009 2009 CD cord-280571-ntgt5hy9 267 13 influenza influenza NN cord-280571-ntgt5hy9 267 14 A a DT cord-280571-ntgt5hy9 267 15 H1N1 H1N1 NNP cord-280571-ntgt5hy9 267 16 outbreak outbreak NN cord-280571-ntgt5hy9 267 17 , , , cord-280571-ntgt5hy9 267 18 the the DT cord-280571-ntgt5hy9 267 19 NS NS NNP cord-280571-ntgt5hy9 267 20 - - HYPH cord-280571-ntgt5hy9 267 21 LIJHS LIJHS NNP cord-280571-ntgt5hy9 267 22 laboratories laboratory NNS cord-280571-ntgt5hy9 267 23 ' ' POS cord-280571-ntgt5hy9 267 24 respiratory respiratory JJ cord-280571-ntgt5hy9 267 25 virus virus NN cord-280571-ntgt5hy9 267 26 testing testing NN cord-280571-ntgt5hy9 267 27 volume volume NN cord-280571-ntgt5hy9 267 28 increased increase VBD cord-280571-ntgt5hy9 267 29 from from IN cord-280571-ntgt5hy9 267 30 a a DT cord-280571-ntgt5hy9 267 31 baseline baseline NN cord-280571-ntgt5hy9 267 32 of of IN cord-280571-ntgt5hy9 267 33 225 225 CD cord-280571-ntgt5hy9 267 34 tests test NNS cord-280571-ntgt5hy9 267 35 per per IN cord-280571-ntgt5hy9 267 36 day day NN cord-280571-ntgt5hy9 267 37 to to IN cord-280571-ntgt5hy9 267 38 more more JJR cord-280571-ntgt5hy9 267 39 than than IN cord-280571-ntgt5hy9 267 40 950 950 CD cord-280571-ntgt5hy9 267 41 tests test NNS cord-280571-ntgt5hy9 267 42 per per IN cord-280571-ntgt5hy9 267 43 day day NN cord-280571-ntgt5hy9 267 44 , , , cord-280571-ntgt5hy9 267 45 within within IN cord-280571-ntgt5hy9 267 46 3 3 CD cord-280571-ntgt5hy9 267 47 days day NNS cord-280571-ntgt5hy9 267 48 . . . cord-280571-ntgt5hy9 268 1 It -PRON- PRP cord-280571-ntgt5hy9 268 2 was be VBD cord-280571-ntgt5hy9 268 3 clear clear JJ cord-280571-ntgt5hy9 268 4 from from IN cord-280571-ntgt5hy9 268 5 the the DT cord-280571-ntgt5hy9 268 6 first first JJ cord-280571-ntgt5hy9 268 7 week week NN cord-280571-ntgt5hy9 268 8 of of IN cord-280571-ntgt5hy9 268 9 the the DT cord-280571-ntgt5hy9 268 10 outbreak outbreak NN cord-280571-ntgt5hy9 268 11 that that WDT cord-280571-ntgt5hy9 268 12 the the DT cord-280571-ntgt5hy9 268 13 laboratory laboratory NN cord-280571-ntgt5hy9 268 14 urgently urgently RB cord-280571-ntgt5hy9 268 15 needed need VBD cord-280571-ntgt5hy9 268 16 to to TO cord-280571-ntgt5hy9 268 17 switch switch VB cord-280571-ntgt5hy9 268 18 all all DT cord-280571-ntgt5hy9 268 19 influenza influenza NN cord-280571-ntgt5hy9 268 20 testing test VBG cord-280571-ntgt5hy9 268 21 to to IN cord-280571-ntgt5hy9 268 22 molecular molecular JJ cord-280571-ntgt5hy9 268 23 methods method NNS cord-280571-ntgt5hy9 268 24 to to TO cord-280571-ntgt5hy9 268 25 obtain obtain VB cord-280571-ntgt5hy9 268 26 sufficient sufficient JJ cord-280571-ntgt5hy9 268 27 diagnostic diagnostic JJ cord-280571-ntgt5hy9 268 28 sensitivity sensitivity NN cord-280571-ntgt5hy9 268 29 and and CC cord-280571-ntgt5hy9 268 30 to to TO cord-280571-ntgt5hy9 268 31 subtype subtype VB cord-280571-ntgt5hy9 268 32 the the DT cord-280571-ntgt5hy9 268 33 influenza influenza NN cord-280571-ntgt5hy9 268 34 strains strain NNS cord-280571-ntgt5hy9 268 35 . . . cord-280571-ntgt5hy9 269 1 Fortunately fortunately RB cord-280571-ntgt5hy9 269 2 , , , cord-280571-ntgt5hy9 269 3 an an DT cord-280571-ntgt5hy9 269 4 FDA FDA NNP cord-280571-ntgt5hy9 269 5 - - HYPH cord-280571-ntgt5hy9 269 6 approved approve VBN cord-280571-ntgt5hy9 269 7 test test NN cord-280571-ntgt5hy9 269 8 , , , cord-280571-ntgt5hy9 269 9 the the DT cord-280571-ntgt5hy9 269 10 Luminex Luminex NNP cord-280571-ntgt5hy9 269 11 xTAG xTAG VBD cord-280571-ntgt5hy9 269 12 RVP RVP NNP cord-280571-ntgt5hy9 269 13 test test NN cord-280571-ntgt5hy9 269 14 , , , cord-280571-ntgt5hy9 269 15 was be VBD cord-280571-ntgt5hy9 269 16 available available JJ cord-280571-ntgt5hy9 269 17 and and CC cord-280571-ntgt5hy9 269 18 met meet VBD cord-280571-ntgt5hy9 269 19 our -PRON- PRP$ cord-280571-ntgt5hy9 269 20 diagnostic diagnostic JJ cord-280571-ntgt5hy9 269 21 requirements requirement NNS cord-280571-ntgt5hy9 269 22 [ [ -LRB- cord-280571-ntgt5hy9 269 23 5 5 CD cord-280571-ntgt5hy9 269 24 , , , cord-280571-ntgt5hy9 269 25 24 24 CD cord-280571-ntgt5hy9 269 26 , , , cord-280571-ntgt5hy9 269 27 43 43 CD cord-280571-ntgt5hy9 269 28 ] ] -RRB- cord-280571-ntgt5hy9 269 29 . . . cord-280571-ntgt5hy9 270 1 Laboratories laboratory NNS cord-280571-ntgt5hy9 270 2 must must MD cord-280571-ntgt5hy9 270 3 continue continue VB cord-280571-ntgt5hy9 270 4 to to TO cord-280571-ntgt5hy9 270 5 plan plan VB cord-280571-ntgt5hy9 270 6 for for IN cord-280571-ntgt5hy9 270 7 future future JJ cord-280571-ntgt5hy9 270 8 pandemic pandemic NN cord-280571-ntgt5hy9 270 9 outbreaks outbreak NNS cord-280571-ntgt5hy9 270 10 and and CC cord-280571-ntgt5hy9 270 11 biothreat biothreat NN cord-280571-ntgt5hy9 270 12 events event NNS cord-280571-ntgt5hy9 270 13 . . . cord-280571-ntgt5hy9 271 1 Therefore therefore RB cord-280571-ntgt5hy9 271 2 , , , cord-280571-ntgt5hy9 271 3 laboratories laboratory NNS cord-280571-ntgt5hy9 271 4 are be VBP cord-280571-ntgt5hy9 271 5 constantly constantly RB cord-280571-ntgt5hy9 271 6 under under IN cord-280571-ntgt5hy9 271 7 pressure pressure NN cord-280571-ntgt5hy9 271 8 to to TO cord-280571-ntgt5hy9 271 9 expand expand VB cord-280571-ntgt5hy9 271 10 testing testing NN cord-280571-ntgt5hy9 271 11 and and CC cord-280571-ntgt5hy9 271 12 meet meet VB cord-280571-ntgt5hy9 271 13 the the DT cord-280571-ntgt5hy9 271 14 demands demand NNS cord-280571-ntgt5hy9 271 15 of of IN cord-280571-ntgt5hy9 271 16 their -PRON- PRP$ cord-280571-ntgt5hy9 271 17 clinical clinical JJ cord-280571-ntgt5hy9 271 18 staff staff NN cord-280571-ntgt5hy9 271 19 and and CC cord-280571-ntgt5hy9 271 20 their -PRON- PRP$ cord-280571-ntgt5hy9 271 21 diverse diverse JJ cord-280571-ntgt5hy9 271 22 patient patient JJ cord-280571-ntgt5hy9 271 23 populations population NNS cord-280571-ntgt5hy9 271 24 . . . cord-280571-ntgt5hy9 272 1 To to TO cord-280571-ntgt5hy9 272 2 do do VB cord-280571-ntgt5hy9 272 3 this this DT cord-280571-ntgt5hy9 272 4 , , , cord-280571-ntgt5hy9 272 5 laboratories laboratory NNS cord-280571-ntgt5hy9 272 6 must must MD cord-280571-ntgt5hy9 272 7 provide provide VB cord-280571-ntgt5hy9 272 8 clinically clinically RB cord-280571-ntgt5hy9 272 9 relevant relevant JJ cord-280571-ntgt5hy9 272 10 , , , cord-280571-ntgt5hy9 272 11 high high JJ cord-280571-ntgt5hy9 272 12 - - HYPH cord-280571-ntgt5hy9 272 13 quality quality NN cord-280571-ntgt5hy9 272 14 , , , cord-280571-ntgt5hy9 272 15 cost cost NN cord-280571-ntgt5hy9 272 16 - - HYPH cord-280571-ntgt5hy9 272 17 effective effective JJ cord-280571-ntgt5hy9 272 18 NAATS NAATS NNP cord-280571-ntgt5hy9 272 19 that that WDT cord-280571-ntgt5hy9 272 20 are be VBP cord-280571-ntgt5hy9 272 21 preferably preferably RB cord-280571-ntgt5hy9 272 22 FDA FDA NNP cord-280571-ntgt5hy9 272 23 approved approve VBN cord-280571-ntgt5hy9 272 24 / / SYM cord-280571-ntgt5hy9 272 25 cleared clear VBN cord-280571-ntgt5hy9 272 26 . . . cord-280571-ntgt5hy9 273 1 As as IN cord-280571-ntgt5hy9 273 2 we -PRON- PRP cord-280571-ntgt5hy9 273 3 move move VBP cord-280571-ntgt5hy9 273 4 forward forward RB cord-280571-ntgt5hy9 273 5 , , , cord-280571-ntgt5hy9 273 6 we -PRON- PRP cord-280571-ntgt5hy9 273 7 request request VBP cord-280571-ntgt5hy9 273 8 that that IN cord-280571-ntgt5hy9 273 9 the the DT cord-280571-ntgt5hy9 273 10 FDA FDA NNP cord-280571-ntgt5hy9 273 11 work work NN cord-280571-ntgt5hy9 273 12 closely closely RB cord-280571-ntgt5hy9 273 13 with with IN cord-280571-ntgt5hy9 273 14 such such JJ cord-280571-ntgt5hy9 273 15 organizations organization NNS cord-280571-ntgt5hy9 273 16 as as IN cord-280571-ntgt5hy9 273 17 the the DT cord-280571-ntgt5hy9 273 18 Infectious Infectious NNP cord-280571-ntgt5hy9 273 19 Diseases Diseases NNPS cord-280571-ntgt5hy9 273 20 Society Society NNP cord-280571-ntgt5hy9 273 21 of of IN cord-280571-ntgt5hy9 273 22 America America NNP cord-280571-ntgt5hy9 273 23 and and CC cord-280571-ntgt5hy9 273 24 the the DT cord-280571-ntgt5hy9 273 25 American American NNP cord-280571-ntgt5hy9 273 26 Society Society NNP cord-280571-ntgt5hy9 273 27 for for IN cord-280571-ntgt5hy9 273 28 Microbiology Microbiology NNP cord-280571-ntgt5hy9 273 29 , , , cord-280571-ntgt5hy9 273 30 with with IN cord-280571-ntgt5hy9 273 31 laboratory laboratory NN cord-280571-ntgt5hy9 273 32 directors director NNS cord-280571-ntgt5hy9 273 33 , , , cord-280571-ntgt5hy9 273 34 and and CC cord-280571-ntgt5hy9 273 35 with with IN cord-280571-ntgt5hy9 273 36 IVD IVD NNP cord-280571-ntgt5hy9 273 37 device device NN cord-280571-ntgt5hy9 273 38 manufacturers manufacturer NNS cord-280571-ntgt5hy9 273 39 so so IN cord-280571-ntgt5hy9 273 40 that that IN cord-280571-ntgt5hy9 273 41 this this DT cord-280571-ntgt5hy9 273 42 goal goal NN cord-280571-ntgt5hy9 273 43 can can MD cord-280571-ntgt5hy9 273 44 be be VB cord-280571-ntgt5hy9 273 45 met meet VBN cord-280571-ntgt5hy9 273 46 . . . cord-280571-ntgt5hy9 274 1 The the DT cord-280571-ntgt5hy9 274 2 labor labor NN cord-280571-ntgt5hy9 274 3 - - HYPH cord-280571-ntgt5hy9 274 4 intensive intensive JJ cord-280571-ntgt5hy9 274 5 , , , cord-280571-ntgt5hy9 274 6 complex complex JJ cord-280571-ntgt5hy9 274 7 methods method NNS cord-280571-ntgt5hy9 274 8 and and CC cord-280571-ntgt5hy9 274 9 platforms platform NNS cord-280571-ntgt5hy9 274 10 of of IN cord-280571-ntgt5hy9 274 11 yesterday yesterday NN cord-280571-ntgt5hy9 274 12 have have VBP cord-280571-ntgt5hy9 274 13 evolved evolve VBN cord-280571-ntgt5hy9 274 14 into into IN cord-280571-ntgt5hy9 274 15 simpler simple JJR cord-280571-ntgt5hy9 274 16 , , , cord-280571-ntgt5hy9 274 17 user user VB cord-280571-ntgt5hy9 274 18 friendly friendly JJ cord-280571-ntgt5hy9 274 19 versions version NNS cord-280571-ntgt5hy9 274 20 that that WDT cord-280571-ntgt5hy9 274 21 can can MD cord-280571-ntgt5hy9 274 22 be be VB cord-280571-ntgt5hy9 274 23 applicable applicable JJ cord-280571-ntgt5hy9 274 24 to to IN cord-280571-ntgt5hy9 274 25 all all DT cord-280571-ntgt5hy9 274 26 health health NN cord-280571-ntgt5hy9 274 27 care care NN cord-280571-ntgt5hy9 274 28 settings setting NNS cord-280571-ntgt5hy9 274 29 . . . cord-280571-ntgt5hy9 275 1 We -PRON- PRP cord-280571-ntgt5hy9 275 2 encourage encourage VBP cord-280571-ntgt5hy9 275 3 the the DT cord-280571-ntgt5hy9 275 4 FDA FDA NNP cord-280571-ntgt5hy9 275 5 to to TO cord-280571-ntgt5hy9 275 6 allow allow VB cord-280571-ntgt5hy9 275 7 the the DT cord-280571-ntgt5hy9 275 8 submission submission NN cord-280571-ntgt5hy9 275 9 process process NN cord-280571-ntgt5hy9 275 10 to to TO cord-280571-ntgt5hy9 275 11 evolve evolve VB cord-280571-ntgt5hy9 275 12 in in IN cord-280571-ntgt5hy9 275 13 a a DT cord-280571-ntgt5hy9 275 14 similar similar JJ cord-280571-ntgt5hy9 275 15 manner manner NN cord-280571-ntgt5hy9 275 16 . . . cord-280571-ntgt5hy9 276 1 No no RB cord-280571-ntgt5hy9 276 2 longer long RBR cord-280571-ntgt5hy9 276 3 are be VBP cord-280571-ntgt5hy9 276 4 the the DT cord-280571-ntgt5hy9 276 5 old old JJ cord-280571-ntgt5hy9 276 6 ' ' '' cord-280571-ntgt5hy9 276 7 ' ' `` cord-280571-ntgt5hy9 276 8 gold gold NN cord-280571-ntgt5hy9 276 9 standards standard NNS cord-280571-ntgt5hy9 276 10 ' ' '' cord-280571-ntgt5hy9 276 11 ' ' '' cord-280571-ntgt5hy9 276 12 of of IN cord-280571-ntgt5hy9 276 13 culture culture NN cord-280571-ntgt5hy9 276 14 applicable applicable JJ cord-280571-ntgt5hy9 276 15 , , , cord-280571-ntgt5hy9 276 16 and and CC cord-280571-ntgt5hy9 276 17 new new JJ cord-280571-ntgt5hy9 276 18 ways way NNS cord-280571-ntgt5hy9 276 19 to to TO cord-280571-ntgt5hy9 276 20 evaluate evaluate VB cord-280571-ntgt5hy9 276 21 these these DT cord-280571-ntgt5hy9 276 22 tests test NNS cord-280571-ntgt5hy9 276 23 must must MD cord-280571-ntgt5hy9 276 24 be be VB cord-280571-ntgt5hy9 276 25 considered consider VBN cord-280571-ntgt5hy9 276 26 [ [ -LRB- cord-280571-ntgt5hy9 276 27 44 44 CD cord-280571-ntgt5hy9 276 28 ] ] -RRB- cord-280571-ntgt5hy9 276 29 so so IN cord-280571-ntgt5hy9 276 30 that that DT cord-280571-ntgt5hy9 276 31 accurate accurate JJ cord-280571-ntgt5hy9 276 32 performance performance NN cord-280571-ntgt5hy9 276 33 characteristics characteristic NNS cord-280571-ntgt5hy9 276 34 can can MD cord-280571-ntgt5hy9 276 35 be be VB cord-280571-ntgt5hy9 276 36 determined determine VBN cord-280571-ntgt5hy9 276 37 in in IN cord-280571-ntgt5hy9 276 38 a a DT cord-280571-ntgt5hy9 276 39 cost cost NN cord-280571-ntgt5hy9 276 40 - - HYPH cord-280571-ntgt5hy9 276 41 effective effective JJ cord-280571-ntgt5hy9 276 42 manner manner NN cord-280571-ntgt5hy9 276 43 . . . cord-280571-ntgt5hy9 277 1 The the DT cord-280571-ntgt5hy9 277 2 latter latter JJ cord-280571-ntgt5hy9 277 3 is be VBZ cord-280571-ntgt5hy9 277 4 especially especially RB cord-280571-ntgt5hy9 277 5 true true JJ cord-280571-ntgt5hy9 277 6 for for IN cord-280571-ntgt5hy9 277 7 low low JJ cord-280571-ntgt5hy9 277 8 - - HYPH cord-280571-ntgt5hy9 277 9 volume volume NN cord-280571-ntgt5hy9 277 10 but but CC cord-280571-ntgt5hy9 277 11 highly highly RB cord-280571-ntgt5hy9 277 12 relevant relevant JJ cord-280571-ntgt5hy9 277 13 assays assay NNS cord-280571-ntgt5hy9 277 14 , , , cord-280571-ntgt5hy9 277 15 such such JJ cord-280571-ntgt5hy9 277 16 as as IN cord-280571-ntgt5hy9 277 17 quantitative quantitative JJ cord-280571-ntgt5hy9 277 18 NAATs naat NNS cord-280571-ntgt5hy9 277 19 for for IN cord-280571-ntgt5hy9 277 20 transplantation transplantation NN cord-280571-ntgt5hy9 277 21 monitoring monitoring NN cord-280571-ntgt5hy9 277 22 . . . cord-280571-ntgt5hy9 278 1 In in IN cord-280571-ntgt5hy9 278 2 a a DT cord-280571-ntgt5hy9 278 3 reasonable reasonable JJ cord-280571-ntgt5hy9 278 4 and and CC cord-280571-ntgt5hy9 278 5 clear clear JJ cord-280571-ntgt5hy9 278 6 regulatory regulatory JJ cord-280571-ntgt5hy9 278 7 environment environment NN cord-280571-ntgt5hy9 278 8 , , , cord-280571-ntgt5hy9 278 9 the the DT cord-280571-ntgt5hy9 278 10 IVD IVD NNP cord-280571-ntgt5hy9 278 11 device device NN cord-280571-ntgt5hy9 278 12 manufacturers manufacturer NNS cord-280571-ntgt5hy9 278 13 will will MD cord-280571-ntgt5hy9 278 14 succeed succeed VB cord-280571-ntgt5hy9 278 15 in in IN cord-280571-ntgt5hy9 278 16 bringing bring VBG cord-280571-ntgt5hy9 278 17 their -PRON- PRP$ cord-280571-ntgt5hy9 278 18 NAATS NAATS NNP cord-280571-ntgt5hy9 278 19 through through IN cord-280571-ntgt5hy9 278 20 the the DT cord-280571-ntgt5hy9 278 21 approval approval NN cord-280571-ntgt5hy9 278 22 process process NN cord-280571-ntgt5hy9 278 23 . . . cord-280571-ntgt5hy9 279 1 The the DT cord-280571-ntgt5hy9 279 2 role role NN cord-280571-ntgt5hy9 279 3 of of IN cord-280571-ntgt5hy9 279 4 antimicrobial antimicrobial JJ cord-280571-ntgt5hy9 279 5 management management NN cord-280571-ntgt5hy9 279 6 programs program NNS cord-280571-ntgt5hy9 279 7 in in IN cord-280571-ntgt5hy9 279 8 optimizing optimize VBG cord-280571-ntgt5hy9 279 9 antibiotic antibiotic JJ cord-280571-ntgt5hy9 279 10 prescribing prescribing NN cord-280571-ntgt5hy9 279 11 within within IN cord-280571-ntgt5hy9 279 12 hospitals hospital NNS cord-280571-ntgt5hy9 279 13 Antimicrobial antimicrobial JJ cord-280571-ntgt5hy9 279 14 stewardship stewardship NN cord-280571-ntgt5hy9 279 15 programs program NNS cord-280571-ntgt5hy9 279 16 in in IN cord-280571-ntgt5hy9 279 17 health health NN cord-280571-ntgt5hy9 279 18 care care NN cord-280571-ntgt5hy9 279 19 systems system NNS cord-280571-ntgt5hy9 280 1 Excessive excessive JJ cord-280571-ntgt5hy9 280 2 antibiotic antibiotic JJ cord-280571-ntgt5hy9 280 3 use use NN cord-280571-ntgt5hy9 280 4 for for IN cord-280571-ntgt5hy9 280 5 acute acute JJ cord-280571-ntgt5hy9 280 6 respiratory respiratory JJ cord-280571-ntgt5hy9 280 7 infections infection NNS cord-280571-ntgt5hy9 280 8 in in IN cord-280571-ntgt5hy9 280 9 the the DT cord-280571-ntgt5hy9 280 10 United United NNP cord-280571-ntgt5hy9 280 11 States States NNP cord-280571-ntgt5hy9 280 12 Lack Lack NNP cord-280571-ntgt5hy9 280 13 of of IN cord-280571-ntgt5hy9 280 14 sensitivity sensitivity NN cord-280571-ntgt5hy9 280 15 of of IN cord-280571-ntgt5hy9 280 16 rapid rapid JJ cord-280571-ntgt5hy9 280 17 antigen antigen NN cord-280571-ntgt5hy9 280 18 tests test NNS cord-280571-ntgt5hy9 280 19 for for IN cord-280571-ntgt5hy9 280 20 the the DT cord-280571-ntgt5hy9 280 21 diagnosis diagnosis NN cord-280571-ntgt5hy9 280 22 of of IN cord-280571-ntgt5hy9 280 23 respiratory respiratory JJ cord-280571-ntgt5hy9 280 24 syncytial syncytial JJ cord-280571-ntgt5hy9 280 25 virus virus NN cord-280571-ntgt5hy9 280 26 infection infection NN cord-280571-ntgt5hy9 280 27 in in IN cord-280571-ntgt5hy9 280 28 adults adult NNS cord-280571-ntgt5hy9 280 29 Evaluation Evaluation NNP cord-280571-ntgt5hy9 280 30 of of IN cord-280571-ntgt5hy9 280 31 multiple multiple JJ cord-280571-ntgt5hy9 280 32 test test NN cord-280571-ntgt5hy9 280 33 methods method NNS cord-280571-ntgt5hy9 280 34 for for IN cord-280571-ntgt5hy9 280 35 the the DT cord-280571-ntgt5hy9 280 36 detection detection NN cord-280571-ntgt5hy9 280 37 of of IN cord-280571-ntgt5hy9 280 38 the the DT cord-280571-ntgt5hy9 280 39 novel novel JJ cord-280571-ntgt5hy9 280 40 2009 2009 CD cord-280571-ntgt5hy9 280 41 influenza influenza NN cord-280571-ntgt5hy9 280 42 A a NN cord-280571-ntgt5hy9 280 43 ( ( -LRB- cord-280571-ntgt5hy9 280 44 H1N1 H1N1 NNP cord-280571-ntgt5hy9 280 45 ) ) -RRB- cord-280571-ntgt5hy9 280 46 during during IN cord-280571-ntgt5hy9 280 47 the the DT cord-280571-ntgt5hy9 280 48 New New NNP cord-280571-ntgt5hy9 280 49 York York NNP cord-280571-ntgt5hy9 280 50 City City NNP cord-280571-ntgt5hy9 280 51 outbreak outbreak NN cord-280571-ntgt5hy9 280 52 Role role NN cord-280571-ntgt5hy9 280 53 of of IN cord-280571-ntgt5hy9 280 54 cell cell NN cord-280571-ntgt5hy9 280 55 culture culture NN cord-280571-ntgt5hy9 280 56 for for IN cord-280571-ntgt5hy9 280 57 virus virus NN cord-280571-ntgt5hy9 280 58 detection detection NN cord-280571-ntgt5hy9 280 59 in in IN cord-280571-ntgt5hy9 280 60 the the DT cord-280571-ntgt5hy9 280 61 age age NN cord-280571-ntgt5hy9 280 62 of of IN cord-280571-ntgt5hy9 280 63 technology technology NN cord-280571-ntgt5hy9 280 64 Rapid rapid JJ cord-280571-ntgt5hy9 280 65 diagnosis diagnosis NN cord-280571-ntgt5hy9 280 66 of of IN cord-280571-ntgt5hy9 280 67 respiratory respiratory JJ cord-280571-ntgt5hy9 280 68 syncytial syncytial JJ cord-280571-ntgt5hy9 280 69 virus virus NN cord-280571-ntgt5hy9 280 70 infections infection NNS cord-280571-ntgt5hy9 280 71 in in IN cord-280571-ntgt5hy9 280 72 immunocompromised immunocompromised JJ cord-280571-ntgt5hy9 280 73 adults adult NNS cord-280571-ntgt5hy9 281 1 Quantitative quantitative JJ cord-280571-ntgt5hy9 281 2 shedding shed VBG cord-280571-ntgt5hy9 281 3 patterns pattern NNS cord-280571-ntgt5hy9 281 4 of of IN cord-280571-ntgt5hy9 281 5 respiratory respiratory JJ cord-280571-ntgt5hy9 281 6 syncytial syncytial JJ cord-280571-ntgt5hy9 281 7 virus virus NN cord-280571-ntgt5hy9 281 8 in in IN cord-280571-ntgt5hy9 281 9 infants infant NNS cord-280571-ntgt5hy9 281 10 Diagnostic diagnostic JJ cord-280571-ntgt5hy9 281 11 assays assay NNS cord-280571-ntgt5hy9 281 12 for for IN cord-280571-ntgt5hy9 281 13 respiratory respiratory JJ cord-280571-ntgt5hy9 281 14 syncytial syncytial JJ cord-280571-ntgt5hy9 281 15 virus virus NN cord-280571-ntgt5hy9 281 16 . . . cord-280571-ntgt5hy9 282 1 Pediatr Pediatr NNP cord-280571-ntgt5hy9 282 2 Comparison Comparison NNP cord-280571-ntgt5hy9 282 3 of of IN cord-280571-ntgt5hy9 282 4 viral viral JJ cord-280571-ntgt5hy9 282 5 isolation isolation NN cord-280571-ntgt5hy9 282 6 and and CC cord-280571-ntgt5hy9 282 7 multiplex multiplex JJ cord-280571-ntgt5hy9 282 8 real real JJ cord-280571-ntgt5hy9 282 9 - - HYPH cord-280571-ntgt5hy9 282 10 time time NN cord-280571-ntgt5hy9 282 11 reverse reverse NN cord-280571-ntgt5hy9 282 12 transcription transcription NN cord-280571-ntgt5hy9 282 13 - - HYPH cord-280571-ntgt5hy9 282 14 PCR pcr NN cord-280571-ntgt5hy9 282 15 for for IN cord-280571-ntgt5hy9 282 16 confirmation confirmation NN cord-280571-ntgt5hy9 282 17 of of IN cord-280571-ntgt5hy9 282 18 respiratory respiratory JJ cord-280571-ntgt5hy9 282 19 syncytial syncytial JJ cord-280571-ntgt5hy9 282 20 virus virus NN cord-280571-ntgt5hy9 282 21 and and CC cord-280571-ntgt5hy9 282 22 influenza influenza NN cord-280571-ntgt5hy9 282 23 virus virus NN cord-280571-ntgt5hy9 282 24 detection detection NN cord-280571-ntgt5hy9 282 25 by by IN cord-280571-ntgt5hy9 282 26 antigen antigen NNP cord-280571-ntgt5hy9 282 27 immunoassays immunoassays NNP cord-280571-ntgt5hy9 283 1 The the DT cord-280571-ntgt5hy9 283 2 unrecognized unrecognized JJ cord-280571-ntgt5hy9 283 3 burden burden NN cord-280571-ntgt5hy9 283 4 of of IN cord-280571-ntgt5hy9 283 5 influenza influenza NN cord-280571-ntgt5hy9 283 6 in in IN cord-280571-ntgt5hy9 283 7 young young JJ cord-280571-ntgt5hy9 283 8 children child NNS cord-280571-ntgt5hy9 283 9 Oseltamivir Oseltamivir NNP cord-280571-ntgt5hy9 283 10 - - HYPH cord-280571-ntgt5hy9 283 11 resistant resistant JJ cord-280571-ntgt5hy9 283 12 2009 2009 CD cord-280571-ntgt5hy9 283 13 pandemic pandemic NN cord-280571-ntgt5hy9 283 14 influenza influenza NN cord-280571-ntgt5hy9 283 15 A A NNP cord-280571-ntgt5hy9 283 16 ( ( -LRB- cord-280571-ntgt5hy9 283 17 H1N1 H1N1 NNP cord-280571-ntgt5hy9 283 18 ) ) -RRB- cord-280571-ntgt5hy9 283 19 virus virus NN cord-280571-ntgt5hy9 283 20 infection infection NN cord-280571-ntgt5hy9 283 21 in in IN cord-280571-ntgt5hy9 283 22 two two CD cord-280571-ntgt5hy9 283 23 summer summer NN cord-280571-ntgt5hy9 283 24 campers camper NNS cord-280571-ntgt5hy9 283 25 receiving receive VBG cord-280571-ntgt5hy9 283 26 prophylaxis prophylaxis NN cord-280571-ntgt5hy9 283 27 - - HYPH cord-280571-ntgt5hy9 283 28 North North NNP cord-280571-ntgt5hy9 283 29 Carolina Carolina NNP cord-280571-ntgt5hy9 283 30 Oseltamivir Oseltamivir NNP cord-280571-ntgt5hy9 283 31 resistant resistant JJ cord-280571-ntgt5hy9 283 32 2009 2009 CD cord-280571-ntgt5hy9 283 33 - - SYM cord-280571-ntgt5hy9 283 34 2010 2010 CD cord-280571-ntgt5hy9 283 35 pandemic pandemic NN cord-280571-ntgt5hy9 283 36 influenza influenza NN cord-280571-ntgt5hy9 283 37 A A NNP cord-280571-ntgt5hy9 283 38 ( ( -LRB- cord-280571-ntgt5hy9 283 39 H1N1 H1N1 NNP cord-280571-ntgt5hy9 283 40 ) ) -RRB- cord-280571-ntgt5hy9 283 41 in in IN cord-280571-ntgt5hy9 283 42 an an DT cord-280571-ntgt5hy9 283 43 immunocompromised immunocompromised JJ cord-280571-ntgt5hy9 283 44 patient patient NN cord-280571-ntgt5hy9 283 45 Comparison comparison NN cord-280571-ntgt5hy9 283 46 of of IN cord-280571-ntgt5hy9 283 47 clinical clinical JJ cord-280571-ntgt5hy9 283 48 features feature NNS cord-280571-ntgt5hy9 283 49 of of IN cord-280571-ntgt5hy9 283 50 pediatric pediatric JJ cord-280571-ntgt5hy9 283 51 RSV RSV NNP cord-280571-ntgt5hy9 283 52 and and CC cord-280571-ntgt5hy9 283 53 human human JJ cord-280571-ntgt5hy9 283 54 metapneumovirus metapneumovirus NNP cord-280571-ntgt5hy9 283 55 infections infection NNS cord-280571-ntgt5hy9 283 56 Clinical clinical JJ cord-280571-ntgt5hy9 283 57 evaluation evaluation NN cord-280571-ntgt5hy9 283 58 of of IN cord-280571-ntgt5hy9 283 59 NucliSENS NucliSENS NNP cord-280571-ntgt5hy9 283 60 magnetic magnetic JJ cord-280571-ntgt5hy9 283 61 extraction extraction NN cord-280571-ntgt5hy9 283 62 and and CC cord-280571-ntgt5hy9 283 63 NucliSENS nuclisens NN cord-280571-ntgt5hy9 283 64 analyte analyte NN cord-280571-ntgt5hy9 283 65 specific specific JJ cord-280571-ntgt5hy9 283 66 reagents reagent NNS cord-280571-ntgt5hy9 283 67 for for IN cord-280571-ntgt5hy9 283 68 the the DT cord-280571-ntgt5hy9 283 69 real real JJ cord-280571-ntgt5hy9 283 70 - - HYPH cord-280571-ntgt5hy9 283 71 time time NN cord-280571-ntgt5hy9 283 72 detection detection NN cord-280571-ntgt5hy9 283 73 of of IN cord-280571-ntgt5hy9 283 74 respiratory respiratory JJ cord-280571-ntgt5hy9 283 75 syncytial syncytial JJ cord-280571-ntgt5hy9 283 76 virus virus NN cord-280571-ntgt5hy9 283 77 ( ( -LRB- cord-280571-ntgt5hy9 283 78 RSV RSV NNP cord-280571-ntgt5hy9 283 79 ) ) -RRB- cord-280571-ntgt5hy9 283 80 in in IN cord-280571-ntgt5hy9 283 81 paediatric paediatric JJ cord-280571-ntgt5hy9 283 82 respiratory respiratory JJ cord-280571-ntgt5hy9 283 83 specimens specimen NNS cord-280571-ntgt5hy9 283 84 Cost cost NN cord-280571-ntgt5hy9 283 85 - - HYPH cord-280571-ntgt5hy9 283 86 effective effective JJ cord-280571-ntgt5hy9 283 87 use use NN cord-280571-ntgt5hy9 283 88 of of IN cord-280571-ntgt5hy9 283 89 rapid rapid JJ cord-280571-ntgt5hy9 283 90 diagnostic diagnostic JJ cord-280571-ntgt5hy9 283 91 techniques technique NNS cord-280571-ntgt5hy9 283 92 in in IN cord-280571-ntgt5hy9 283 93 the the DT cord-280571-ntgt5hy9 283 94 treatment treatment NN cord-280571-ntgt5hy9 283 95 and and CC cord-280571-ntgt5hy9 283 96 prevention prevention NN cord-280571-ntgt5hy9 283 97 of of IN cord-280571-ntgt5hy9 283 98 viral viral JJ cord-280571-ntgt5hy9 283 99 respiratory respiratory JJ cord-280571-ntgt5hy9 283 100 infections infection NNS cord-280571-ntgt5hy9 283 101 Comparison comparison NN cord-280571-ntgt5hy9 283 102 of of IN cord-280571-ntgt5hy9 283 103 rapid rapid JJ cord-280571-ntgt5hy9 283 104 detection detection NN cord-280571-ntgt5hy9 283 105 methods method NNS cord-280571-ntgt5hy9 283 106 for for IN cord-280571-ntgt5hy9 283 107 influenza influenza NN cord-280571-ntgt5hy9 283 108 A a DT cord-280571-ntgt5hy9 283 109 virus virus NN cord-280571-ntgt5hy9 283 110 and and CC cord-280571-ntgt5hy9 283 111 their -PRON- PRP$ cord-280571-ntgt5hy9 283 112 value value NN cord-280571-ntgt5hy9 283 113 in in IN cord-280571-ntgt5hy9 283 114 health health NN cord-280571-ntgt5hy9 283 115 care care NN cord-280571-ntgt5hy9 283 116 - - HYPH cord-280571-ntgt5hy9 283 117 management management NN cord-280571-ntgt5hy9 283 118 of of IN cord-280571-ntgt5hy9 283 119 institutionalized institutionalized JJ cord-280571-ntgt5hy9 283 120 geriatric geriatric JJ cord-280571-ntgt5hy9 283 121 patients patient NNS cord-280571-ntgt5hy9 284 1 Why why WRB cord-280571-ntgt5hy9 284 2 diagnose diagnose VB cord-280571-ntgt5hy9 284 3 influenza influenza NN cord-280571-ntgt5hy9 284 4 in in IN cord-280571-ntgt5hy9 284 5 hospitalized hospitalize VBN cord-280571-ntgt5hy9 284 6 pediatric pediatric JJ cord-280571-ntgt5hy9 284 7 patients patient NNS cord-280571-ntgt5hy9 284 8 ? ? . cord-280571-ntgt5hy9 285 1 Cost cost NN cord-280571-ntgt5hy9 285 2 - - HYPH cord-280571-ntgt5hy9 285 3 effectiveness effectiveness NN cord-280571-ntgt5hy9 285 4 of of IN cord-280571-ntgt5hy9 285 5 rapid rapid JJ cord-280571-ntgt5hy9 285 6 diagnosis diagnosis NN cord-280571-ntgt5hy9 285 7 of of IN cord-280571-ntgt5hy9 285 8 viral viral JJ cord-280571-ntgt5hy9 285 9 respiratory respiratory JJ cord-280571-ntgt5hy9 285 10 tract tract NN cord-280571-ntgt5hy9 285 11 infections infection NNS cord-280571-ntgt5hy9 285 12 in in IN cord-280571-ntgt5hy9 285 13 pediatric pediatric JJ cord-280571-ntgt5hy9 285 14 patients patient NNS cord-280571-ntgt5hy9 286 1 An an DT cord-280571-ntgt5hy9 286 2 outbreak outbreak NN cord-280571-ntgt5hy9 286 3 of of IN cord-280571-ntgt5hy9 286 4 severe severe JJ cord-280571-ntgt5hy9 286 5 respiratory respiratory JJ cord-280571-ntgt5hy9 286 6 tract tract NN cord-280571-ntgt5hy9 286 7 infection infection NN cord-280571-ntgt5hy9 286 8 due due IN cord-280571-ntgt5hy9 286 9 to to IN cord-280571-ntgt5hy9 286 10 human human JJ cord-280571-ntgt5hy9 286 11 metapneumovirus metapneumovirus NN cord-280571-ntgt5hy9 286 12 in in IN cord-280571-ntgt5hy9 286 13 a a DT cord-280571-ntgt5hy9 286 14 longterm longterm JJ cord-280571-ntgt5hy9 286 15 care care NN cord-280571-ntgt5hy9 286 16 facility facility NN cord-280571-ntgt5hy9 286 17 Outbreak outbreak NN cord-280571-ntgt5hy9 286 18 of of IN cord-280571-ntgt5hy9 286 19 human human JJ cord-280571-ntgt5hy9 286 20 metapneumovirus metapneumovirus JJ cord-280571-ntgt5hy9 286 21 infection infection NN cord-280571-ntgt5hy9 286 22 in in IN cord-280571-ntgt5hy9 286 23 psychiatric psychiatric JJ cord-280571-ntgt5hy9 286 24 inpatients inpatient NNS cord-280571-ntgt5hy9 286 25 : : : cord-280571-ntgt5hy9 286 26 implications implication NNS cord-280571-ntgt5hy9 286 27 for for IN cord-280571-ntgt5hy9 286 28 directly directly RB cord-280571-ntgt5hy9 286 29 observed observe VBN cord-280571-ntgt5hy9 286 30 use use NN cord-280571-ntgt5hy9 286 31 of of IN cord-280571-ntgt5hy9 287 1 alcohol alcohol NN cord-280571-ntgt5hy9 287 2 hand hand NN cord-280571-ntgt5hy9 287 3 rub rub NN cord-280571-ntgt5hy9 287 4 in in IN cord-280571-ntgt5hy9 287 5 prevention prevention NN cord-280571-ntgt5hy9 287 6 of of IN cord-280571-ntgt5hy9 287 7 nosocomial nosocomial JJ cord-280571-ntgt5hy9 287 8 outbreaks outbreak NNS cord-280571-ntgt5hy9 287 9 Outbreak outbreak NN cord-280571-ntgt5hy9 287 10 of of IN cord-280571-ntgt5hy9 287 11 swine swine NN cord-280571-ntgt5hy9 287 12 - - HYPH cord-280571-ntgt5hy9 287 13 origin origin NN cord-280571-ntgt5hy9 287 14 influenza influenza NN cord-280571-ntgt5hy9 287 15 A A NNP cord-280571-ntgt5hy9 287 16 ( ( -LRB- cord-280571-ntgt5hy9 287 17 H1N1 H1N1 NNP cord-280571-ntgt5hy9 287 18 ) ) -RRB- cord-280571-ntgt5hy9 287 19 virus virus NN cord-280571-ntgt5hy9 287 20 infection infection NN cord-280571-ntgt5hy9 287 21 - - : cord-280571-ntgt5hy9 287 22 Mexico Mexico NNP cord-280571-ntgt5hy9 287 23 Swine swine NN cord-280571-ntgt5hy9 287 24 - - HYPH cord-280571-ntgt5hy9 287 25 origin origin NN cord-280571-ntgt5hy9 287 26 influenza influenza NN cord-280571-ntgt5hy9 287 27 A a NN cord-280571-ntgt5hy9 287 28 ( ( -LRB- cord-280571-ntgt5hy9 287 29 H1N1 H1N1 NNP cord-280571-ntgt5hy9 287 30 ) ) -RRB- cord-280571-ntgt5hy9 287 31 virus virus NN cord-280571-ntgt5hy9 287 32 infections infection NNS cord-280571-ntgt5hy9 287 33 in in IN cord-280571-ntgt5hy9 287 34 a a DT cord-280571-ntgt5hy9 287 35 school school NN cord-280571-ntgt5hy9 287 36 Likelihood likelihood NN cord-280571-ntgt5hy9 287 37 that that IN cord-280571-ntgt5hy9 287 38 an an DT cord-280571-ntgt5hy9 287 39 unsubtypeable unsubtypeable JJ cord-280571-ntgt5hy9 287 40 influenza influenza NN cord-280571-ntgt5hy9 287 41 A a DT cord-280571-ntgt5hy9 287 42 result result NN cord-280571-ntgt5hy9 287 43 in in IN cord-280571-ntgt5hy9 287 44 the the DT cord-280571-ntgt5hy9 287 45 Luminex Luminex NNP cord-280571-ntgt5hy9 287 46 xTAG xTAG VBD cord-280571-ntgt5hy9 287 47 Respiratory Respiratory NNP cord-280571-ntgt5hy9 287 48 Virus Virus NNP cord-280571-ntgt5hy9 287 49 Panel Panel NNP cord-280571-ntgt5hy9 287 50 is be VBZ cord-280571-ntgt5hy9 287 51 indicative indicative JJ cord-280571-ntgt5hy9 287 52 of of IN cord-280571-ntgt5hy9 287 53 novel novel JJ cord-280571-ntgt5hy9 287 54 A A NNP cord-280571-ntgt5hy9 287 55 / / SYM cord-280571-ntgt5hy9 287 56 H1N1 H1N1 NNP cord-280571-ntgt5hy9 287 57 ( ( -LRB- cord-280571-ntgt5hy9 287 58 swine swine NN cord-280571-ntgt5hy9 287 59 - - HYPH cord-280571-ntgt5hy9 287 60 like like JJ cord-280571-ntgt5hy9 287 61 ) ) -RRB- cord-280571-ntgt5hy9 287 62 influenza influenza NN cord-280571-ntgt5hy9 287 63 Comprehensive comprehensive JJ cord-280571-ntgt5hy9 287 64 evaluation evaluation NN cord-280571-ntgt5hy9 287 65 of of IN cord-280571-ntgt5hy9 287 66 performance performance NN cord-280571-ntgt5hy9 287 67 , , , cord-280571-ntgt5hy9 287 68 laboratory laboratory NN cord-280571-ntgt5hy9 287 69 application application NN cord-280571-ntgt5hy9 287 70 , , , cord-280571-ntgt5hy9 287 71 and and CC cord-280571-ntgt5hy9 287 72 clinical clinical JJ cord-280571-ntgt5hy9 287 73 usefulness usefulness NN cord-280571-ntgt5hy9 287 74 of of IN cord-280571-ntgt5hy9 287 75 two two CD cord-280571-ntgt5hy9 287 76 direct direct JJ cord-280571-ntgt5hy9 287 77 amplification amplification NN cord-280571-ntgt5hy9 287 78 technologies technology NNS cord-280571-ntgt5hy9 287 79 for for IN cord-280571-ntgt5hy9 287 80 the the DT cord-280571-ntgt5hy9 287 81 detection detection NN cord-280571-ntgt5hy9 287 82 of of IN cord-280571-ntgt5hy9 287 83 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 84 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 85 complex complex JJ cord-280571-ntgt5hy9 287 86 Use use NN cord-280571-ntgt5hy9 287 87 of of IN cord-280571-ntgt5hy9 287 88 the the DT cord-280571-ntgt5hy9 287 89 amplified amplify VBN cord-280571-ntgt5hy9 287 90 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 91 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 92 direct direct JJ cord-280571-ntgt5hy9 287 93 test test NN cord-280571-ntgt5hy9 287 94 in in IN cord-280571-ntgt5hy9 287 95 a a DT cord-280571-ntgt5hy9 287 96 public public JJ cord-280571-ntgt5hy9 287 97 health health NN cord-280571-ntgt5hy9 287 98 laboratory laboratory NN cord-280571-ntgt5hy9 287 99 : : : cord-280571-ntgt5hy9 287 100 test test NN cord-280571-ntgt5hy9 287 101 performance performance NN cord-280571-ntgt5hy9 287 102 and and CC cord-280571-ntgt5hy9 287 103 impact impact NN cord-280571-ntgt5hy9 287 104 on on IN cord-280571-ntgt5hy9 287 105 clinical clinical JJ cord-280571-ntgt5hy9 287 106 care care NN cord-280571-ntgt5hy9 287 107 Evaluation Evaluation NNP cord-280571-ntgt5hy9 287 108 and and CC cord-280571-ntgt5hy9 287 109 follow follow VB cord-280571-ntgt5hy9 287 110 up up IN cord-280571-ntgt5hy9 287 111 of of IN cord-280571-ntgt5hy9 287 112 infectious infectious JJ cord-280571-ntgt5hy9 287 113 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 114 at at IN cord-280571-ntgt5hy9 287 115 the the DT cord-280571-ntgt5hy9 287 116 University University NNP cord-280571-ntgt5hy9 287 117 of of IN cord-280571-ntgt5hy9 287 118 Ottawa Ottawa NNP cord-280571-ntgt5hy9 287 119 Updated update VBD cord-280571-ntgt5hy9 287 120 guidelines guideline NNS cord-280571-ntgt5hy9 287 121 for for IN cord-280571-ntgt5hy9 287 122 the the DT cord-280571-ntgt5hy9 287 123 use use NN cord-280571-ntgt5hy9 287 124 of of IN cord-280571-ntgt5hy9 287 125 nucleic nucleic JJ cord-280571-ntgt5hy9 287 126 acid acid NN cord-280571-ntgt5hy9 287 127 amplification amplification NN cord-280571-ntgt5hy9 287 128 tests test NNS cord-280571-ntgt5hy9 287 129 in in IN cord-280571-ntgt5hy9 287 130 the the DT cord-280571-ntgt5hy9 287 131 diagnosis diagnosis NN cord-280571-ntgt5hy9 287 132 of of IN cord-280571-ntgt5hy9 287 133 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 134 Comparative comparative JJ cord-280571-ntgt5hy9 287 135 evaluation evaluation NN cord-280571-ntgt5hy9 287 136 of of IN cord-280571-ntgt5hy9 287 137 initial initial JJ cord-280571-ntgt5hy9 287 138 and and CC cord-280571-ntgt5hy9 287 139 new new JJ cord-280571-ntgt5hy9 287 140 versions version NNS cord-280571-ntgt5hy9 287 141 of of IN cord-280571-ntgt5hy9 287 142 the the DT cord-280571-ntgt5hy9 287 143 Gen Gen NNP cord-280571-ntgt5hy9 287 144 - - HYPH cord-280571-ntgt5hy9 287 145 Probe Probe NNP cord-280571-ntgt5hy9 287 146 Amplified amplify VBD cord-280571-ntgt5hy9 287 147 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 148 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 149 Direct direct JJ cord-280571-ntgt5hy9 287 150 Test test NN cord-280571-ntgt5hy9 287 151 for for IN cord-280571-ntgt5hy9 287 152 direct direct JJ cord-280571-ntgt5hy9 287 153 detection detection NN cord-280571-ntgt5hy9 287 154 of of IN cord-280571-ntgt5hy9 287 155 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 156 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 157 in in IN cord-280571-ntgt5hy9 287 158 respiratory respiratory JJ cord-280571-ntgt5hy9 287 159 and and CC cord-280571-ntgt5hy9 287 160 nonrespiratory nonrespiratory NN cord-280571-ntgt5hy9 287 161 specimens specimen NNS cord-280571-ntgt5hy9 287 162 Comparison comparison NN cord-280571-ntgt5hy9 287 163 of of IN cord-280571-ntgt5hy9 287 164 the the DT cord-280571-ntgt5hy9 287 165 real real JJ cord-280571-ntgt5hy9 287 166 - - HYPH cord-280571-ntgt5hy9 287 167 time time NN cord-280571-ntgt5hy9 287 168 PCR pcr NN cord-280571-ntgt5hy9 287 169 method method NN cord-280571-ntgt5hy9 287 170 and and CC cord-280571-ntgt5hy9 287 171 the the DT cord-280571-ntgt5hy9 287 172 Gen Gen NNP cord-280571-ntgt5hy9 287 173 - - HYPH cord-280571-ntgt5hy9 287 174 Probe Probe NNP cord-280571-ntgt5hy9 287 175 Amplified amplify VBD cord-280571-ntgt5hy9 287 176 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 177 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 178 Direct direct JJ cord-280571-ntgt5hy9 287 179 Test test NN cord-280571-ntgt5hy9 287 180 for for IN cord-280571-ntgt5hy9 287 181 detection detection NN cord-280571-ntgt5hy9 287 182 of of IN cord-280571-ntgt5hy9 287 183 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 184 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 185 in in IN cord-280571-ntgt5hy9 287 186 pulmonary pulmonary JJ cord-280571-ntgt5hy9 287 187 and and CC cord-280571-ntgt5hy9 287 188 nonpulmonary nonpulmonary JJ cord-280571-ntgt5hy9 287 189 specimens specimens NNP cord-280571-ntgt5hy9 287 190 Evaluation Evaluation NNP cord-280571-ntgt5hy9 287 191 of of IN cord-280571-ntgt5hy9 287 192 Gen Gen NNP cord-280571-ntgt5hy9 287 193 - - HYPH cord-280571-ntgt5hy9 287 194 Probe Probe NNP cord-280571-ntgt5hy9 287 195 Amplified amplify VBD cord-280571-ntgt5hy9 287 196 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 197 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 198 Direct direct JJ cord-280571-ntgt5hy9 287 199 Test test NN cord-280571-ntgt5hy9 287 200 by by IN cord-280571-ntgt5hy9 287 201 using use VBG cord-280571-ntgt5hy9 287 202 respiratory respiratory JJ cord-280571-ntgt5hy9 287 203 and and CC cord-280571-ntgt5hy9 287 204 nonrespiratory nonrespiratory NN cord-280571-ntgt5hy9 287 205 specimens specimen NNS cord-280571-ntgt5hy9 287 206 in in IN cord-280571-ntgt5hy9 287 207 a a DT cord-280571-ntgt5hy9 287 208 tertiary tertiary JJ cord-280571-ntgt5hy9 287 209 care care NN cord-280571-ntgt5hy9 287 210 center center NN cord-280571-ntgt5hy9 287 211 laboratory laboratory NN cord-280571-ntgt5hy9 287 212 Detection Detection NNP cord-280571-ntgt5hy9 287 213 of of IN cord-280571-ntgt5hy9 287 214 Mycobacterum Mycobacterum NNP cord-280571-ntgt5hy9 287 215 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 216 by by IN cord-280571-ntgt5hy9 287 217 PCR PCR NNP cord-280571-ntgt5hy9 287 218 amplification amplification NN cord-280571-ntgt5hy9 287 219 with with IN cord-280571-ntgt5hy9 287 220 pan pan JJ cord-280571-ntgt5hy9 287 221 - - HYPH cord-280571-ntgt5hy9 287 222 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 223 primers primer NNS cord-280571-ntgt5hy9 287 224 and and CC cord-280571-ntgt5hy9 287 225 hybridization hybridization NN cord-280571-ntgt5hy9 287 226 to to IN cord-280571-ntgt5hy9 287 227 an an DT cord-280571-ntgt5hy9 287 228 M. M. NNP cord-280571-ntgt5hy9 287 229 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 230 - - HYPH cord-280571-ntgt5hy9 287 231 specific specific JJ cord-280571-ntgt5hy9 287 232 probe probe NN cord-280571-ntgt5hy9 287 233 Rapid rapid JJ cord-280571-ntgt5hy9 287 234 diagnosis diagnosis NN cord-280571-ntgt5hy9 287 235 of of IN cord-280571-ntgt5hy9 287 236 pulmonary pulmonary JJ cord-280571-ntgt5hy9 287 237 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 238 by by IN cord-280571-ntgt5hy9 287 239 using use VBG cord-280571-ntgt5hy9 287 240 the the DT cord-280571-ntgt5hy9 287 241 Roche Roche NNP cord-280571-ntgt5hy9 287 242 AMPLICOR AMPLICOR NNP cord-280571-ntgt5hy9 287 243 Mycobacterium Mycobacterium NNP cord-280571-ntgt5hy9 287 244 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 245 PCR PCR NNP cord-280571-ntgt5hy9 287 246 test test NN cord-280571-ntgt5hy9 287 247 Use Use NNP cord-280571-ntgt5hy9 287 248 of of IN cord-280571-ntgt5hy9 287 249 Roche Roche NNP cord-280571-ntgt5hy9 287 250 AMPLICOR AMPLICOR NNP cord-280571-ntgt5hy9 287 251 Mycobacterum Mycobacterum NNP cord-280571-ntgt5hy9 287 252 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 253 PCR PCR NNP cord-280571-ntgt5hy9 287 254 in in IN cord-280571-ntgt5hy9 287 255 early early JJ cord-280571-ntgt5hy9 287 256 diagnosis diagnosis NN cord-280571-ntgt5hy9 287 257 of of IN cord-280571-ntgt5hy9 287 258 tuberculous tuberculous JJ cord-280571-ntgt5hy9 287 259 meningitis meningitis NNP cord-280571-ntgt5hy9 287 260 Application Application NNP cord-280571-ntgt5hy9 287 261 of of IN cord-280571-ntgt5hy9 287 262 the the DT cord-280571-ntgt5hy9 287 263 Roche Roche NNP cord-280571-ntgt5hy9 287 264 AMPLICOR AMPLICOR NNP cord-280571-ntgt5hy9 287 265 Mycobacterum Mycobacterum NNP cord-280571-ntgt5hy9 287 266 tuberculosis tuberculosis NN cord-280571-ntgt5hy9 287 267 ( ( -LRB- cord-280571-ntgt5hy9 287 268 PCR PCR NNP cord-280571-ntgt5hy9 287 269 ) ) -RRB- cord-280571-ntgt5hy9 287 270 test test NN cord-280571-ntgt5hy9 287 271 to to IN cord-280571-ntgt5hy9 287 272 specimens specimen NNS cord-280571-ntgt5hy9 287 273 other other JJ cord-280571-ntgt5hy9 287 274 than than IN cord-280571-ntgt5hy9 287 275 respiratory respiratory JJ cord-280571-ntgt5hy9 287 276 secretions secretion NNS cord-280571-ntgt5hy9 287 277 Xpert Xpert NNP cord-280571-ntgt5hy9 287 278 M. M. NNP cord-280571-ntgt5hy9 287 279 tuberculosis/ tuberculosis/ NN cord-280571-ntgt5hy9 287 280 RIF rif NN cord-280571-ntgt5hy9 287 281 for for IN cord-280571-ntgt5hy9 287 282 point point NN cord-280571-ntgt5hy9 287 283 - - HYPH cord-280571-ntgt5hy9 287 284 of of IN cord-280571-ntgt5hy9 287 285 - - HYPH cord-280571-ntgt5hy9 287 286 care care NN cord-280571-ntgt5hy9 287 287 diagnosis diagnosis NN cord-280571-ntgt5hy9 287 288 of of IN cord-280571-ntgt5hy9 287 289 TB TB NNP cord-280571-ntgt5hy9 287 290 in in IN cord-280571-ntgt5hy9 287 291 high high JJ cord-280571-ntgt5hy9 287 292 - - HYPH cord-280571-ntgt5hy9 287 293 HIV HIV NNP cord-280571-ntgt5hy9 287 294 burden burden NN cord-280571-ntgt5hy9 287 295 , , , cord-280571-ntgt5hy9 287 296 resourcelimited resourcelimited JJ cord-280571-ntgt5hy9 287 297 countries country NNS cord-280571-ntgt5hy9 287 298 : : : cord-280571-ntgt5hy9 288 1 hype hype NN cord-280571-ntgt5hy9 288 2 or or CC cord-280571-ntgt5hy9 288 3 hope hope NN cord-280571-ntgt5hy9 288 4 ? ? . cord-280571-ntgt5hy9 289 1 Development development NN cord-280571-ntgt5hy9 289 2 of of IN cord-280571-ntgt5hy9 289 3 a a DT cord-280571-ntgt5hy9 289 4 respiratory respiratory JJ cord-280571-ntgt5hy9 289 5 virus virus NN cord-280571-ntgt5hy9 289 6 panel panel NN cord-280571-ntgt5hy9 289 7 test test NN cord-280571-ntgt5hy9 289 8 for for IN cord-280571-ntgt5hy9 289 9 detection detection NN cord-280571-ntgt5hy9 289 10 of of IN cord-280571-ntgt5hy9 289 11 twenty twenty CD cord-280571-ntgt5hy9 289 12 human human JJ cord-280571-ntgt5hy9 289 13 respiratory respiratory JJ cord-280571-ntgt5hy9 289 14 viruses virus NNS cord-280571-ntgt5hy9 289 15 by by IN cord-280571-ntgt5hy9 289 16 use use NN cord-280571-ntgt5hy9 289 17 of of IN cord-280571-ntgt5hy9 289 18 multiplex multiplex NN cord-280571-ntgt5hy9 289 19 PCR PCR NNP cord-280571-ntgt5hy9 289 20 and and CC cord-280571-ntgt5hy9 289 21 a a DT cord-280571-ntgt5hy9 289 22 fluid fluid JJ cord-280571-ntgt5hy9 289 23 microbead microbead NN cord-280571-ntgt5hy9 289 24 - - HYPH cord-280571-ntgt5hy9 289 25 based base VBN cord-280571-ntgt5hy9 289 26 assay assay NN cord-280571-ntgt5hy9 289 27 Principles principle NNS cord-280571-ntgt5hy9 289 28 of of IN cord-280571-ntgt5hy9 289 29 the the DT cord-280571-ntgt5hy9 289 30 xTAG xtag JJ cord-280571-ntgt5hy9 289 31 respiratory respiratory JJ cord-280571-ntgt5hy9 289 32 viral viral JJ cord-280571-ntgt5hy9 289 33 panel panel NN cord-280571-ntgt5hy9 289 34 assay assay NN cord-280571-ntgt5hy9 289 35 ( ( -LRB- cord-280571-ntgt5hy9 289 36 RVP RVP NNP cord-280571-ntgt5hy9 289 37 assay assay NN cord-280571-ntgt5hy9 289 38 ) ) -RRB- cord-280571-ntgt5hy9 289 39 xTAG xtag JJ cord-280571-ntgt5hy9 289 40 Respiratory Respiratory NNP cord-280571-ntgt5hy9 289 41 Virus Virus NNP cord-280571-ntgt5hy9 289 42 Panel Panel NNP cord-280571-ntgt5hy9 290 1 Luminex Luminex NNP cord-280571-ntgt5hy9 290 2 Molecular Molecular NNP cord-280571-ntgt5hy9 290 3 Diagnostics Diagnostics NNPS cord-280571-ntgt5hy9 290 4 Enhanced enhance VBN cord-280571-ntgt5hy9 290 5 viral viral JJ cord-280571-ntgt5hy9 290 6 etiological etiological JJ cord-280571-ntgt5hy9 290 7 diagnosis diagnosis NN cord-280571-ntgt5hy9 290 8 of of IN cord-280571-ntgt5hy9 290 9 respiratory respiratory JJ cord-280571-ntgt5hy9 290 10 system system NN cord-280571-ntgt5hy9 290 11 infection infection NN cord-280571-ntgt5hy9 290 12 outbreaks outbreak NNS cord-280571-ntgt5hy9 290 13 by by IN cord-280571-ntgt5hy9 290 14 use use NN cord-280571-ntgt5hy9 290 15 of of IN cord-280571-ntgt5hy9 290 16 a a DT cord-280571-ntgt5hy9 290 17 multitarget multitarget NN cord-280571-ntgt5hy9 290 18 nucleic nucleic JJ cord-280571-ntgt5hy9 290 19 acid acid NN cord-280571-ntgt5hy9 290 20 amplification amplification NN cord-280571-ntgt5hy9 290 21 assay assay NN cord-280571-ntgt5hy9 290 22 WI WI NNP cord-280571-ntgt5hy9 290 23 : : : cord-280571-ntgt5hy9 290 24 Gen Gen NNP cord-280571-ntgt5hy9 290 25 - - HYPH cord-280571-ntgt5hy9 290 26 Probe Probe NNP cord-280571-ntgt5hy9 290 27 / / SYM cord-280571-ntgt5hy9 290 28 Prodesse Prodesse NNP cord-280571-ntgt5hy9 290 29 Evaluation Evaluation NNP cord-280571-ntgt5hy9 290 30 of of IN cord-280571-ntgt5hy9 290 31 the the DT cord-280571-ntgt5hy9 290 32 one one CD cord-280571-ntgt5hy9 290 33 - - HYPH cord-280571-ntgt5hy9 290 34 step step NN cord-280571-ntgt5hy9 290 35 multiplex multiplex NN cord-280571-ntgt5hy9 290 36 real real JJ cord-280571-ntgt5hy9 290 37 - - HYPH cord-280571-ntgt5hy9 290 38 time time NN cord-280571-ntgt5hy9 290 39 reverse reverse NN cord-280571-ntgt5hy9 290 40 transcription transcription NN cord-280571-ntgt5hy9 290 41 - - HYPH cord-280571-ntgt5hy9 290 42 PCR PCR NNP cord-280571-ntgt5hy9 290 43 ProFlu-1 ProFlu-1 NNP cord-280571-ntgt5hy9 290 44 assay assay NN cord-280571-ntgt5hy9 290 45 for for IN cord-280571-ntgt5hy9 290 46 detection detection NN cord-280571-ntgt5hy9 290 47 of of IN cord-280571-ntgt5hy9 290 48 influenza influenza NN cord-280571-ntgt5hy9 290 49 A a NN cord-280571-ntgt5hy9 290 50 and and CC cord-280571-ntgt5hy9 290 51 influenza influenza NN cord-280571-ntgt5hy9 290 52 B b NN cord-280571-ntgt5hy9 290 53 viruses virus NNS cord-280571-ntgt5hy9 290 54 and and CC cord-280571-ntgt5hy9 290 55 respiratory respiratory JJ cord-280571-ntgt5hy9 290 56 syncytial syncytial JJ cord-280571-ntgt5hy9 290 57 viruses virus NNS cord-280571-ntgt5hy9 290 58 in in IN cord-280571-ntgt5hy9 290 59 children child NNS cord-280571-ntgt5hy9 290 60 WI WI NNP cord-280571-ntgt5hy9 290 61 : : : cord-280571-ntgt5hy9 290 62 Gen Gen NNP cord-280571-ntgt5hy9 290 63 - - HYPH cord-280571-ntgt5hy9 290 64 Probe Probe NNP cord-280571-ntgt5hy9 290 65 / / SYM cord-280571-ntgt5hy9 290 66 Prodesse Prodesse NNP cord-280571-ntgt5hy9 290 67 WI WI NNP cord-280571-ntgt5hy9 290 68 : : : cord-280571-ntgt5hy9 290 69 Gen Gen NNP cord-280571-ntgt5hy9 290 70 - - HYPH cord-280571-ntgt5hy9 290 71 Probe Probe NNP cord-280571-ntgt5hy9 290 72 / / SYM cord-280571-ntgt5hy9 290 73 Prodesse Prodesse NNP cord-280571-ntgt5hy9 290 74 WI WI NNP cord-280571-ntgt5hy9 290 75 : : : cord-280571-ntgt5hy9 290 76 Gen Gen NNP cord-280571-ntgt5hy9 290 77 - - HYPH cord-280571-ntgt5hy9 290 78 Probe Probe NNP cord-280571-ntgt5hy9 290 79 / / SYM cord-280571-ntgt5hy9 290 80 Prodesse Prodesse NNP cord-280571-ntgt5hy9 290 81 Verigene Verigene NNP cord-280571-ntgt5hy9 290 82 Respiratory Respiratory NNP cord-280571-ntgt5hy9 290 83 Virus virus NN cord-280571-ntgt5hy9 290 84 Nucleic Nucleic NNP cord-280571-ntgt5hy9 290 85 Acid acid NN cord-280571-ntgt5hy9 290 86 Test test NN cord-280571-ntgt5hy9 290 87 IL il NN cord-280571-ntgt5hy9 290 88 : : : cord-280571-ntgt5hy9 291 1 Nanosphere Nanosphere NNP cord-280571-ntgt5hy9 291 2 IL IL NNP cord-280571-ntgt5hy9 291 3 : : : cord-280571-ntgt5hy9 292 1 Nanosphere Nanosphere NNP cord-280571-ntgt5hy9 292 2 Homogeneous homogeneous JJ cord-280571-ntgt5hy9 292 3 detection detection NN cord-280571-ntgt5hy9 292 4 of of IN cord-280571-ntgt5hy9 292 5 unamplified unamplified JJ cord-280571-ntgt5hy9 292 6 genomic genomic JJ cord-280571-ntgt5hy9 292 7 DNA dna NN cord-280571-ntgt5hy9 292 8 sequences sequence NNS cord-280571-ntgt5hy9 292 9 based base VBN cord-280571-ntgt5hy9 292 10 on on IN cord-280571-ntgt5hy9 292 11 colorimetric colorimetric JJ cord-280571-ntgt5hy9 292 12 scatter scatter NN cord-280571-ntgt5hy9 292 13 of of IN cord-280571-ntgt5hy9 292 14 gold gold NN cord-280571-ntgt5hy9 292 15 nanoparticle nanoparticle NN cord-280571-ntgt5hy9 292 16 probes probe NNS cord-280571-ntgt5hy9 292 17 Quality Quality NNP cord-280571-ntgt5hy9 292 18 assurance assurance NN cord-280571-ntgt5hy9 292 19 in in IN cord-280571-ntgt5hy9 292 20 clinical clinical JJ cord-280571-ntgt5hy9 292 21 virology virology NNP cord-280571-ntgt5hy9 292 22 Laboratory Laboratory NNP cord-280571-ntgt5hy9 292 23 surge surge NN cord-280571-ntgt5hy9 292 24 response response NN cord-280571-ntgt5hy9 292 25 to to IN cord-280571-ntgt5hy9 292 26 pandemic pandemic NN cord-280571-ntgt5hy9 292 27 ( ( -LRB- cord-280571-ntgt5hy9 292 28 H1N1 H1N1 NNP cord-280571-ntgt5hy9 292 29 ) ) -RRB- cord-280571-ntgt5hy9 293 1 2009 2009 CD cord-280571-ntgt5hy9 293 2 outbreak outbreak NN cord-280571-ntgt5hy9 293 3 Discrepant Discrepant NNP cord-280571-ntgt5hy9 293 4 analysis analysis NN cord-280571-ntgt5hy9 294 1 : : : cord-280571-ntgt5hy9 294 2 how how WRB cord-280571-ntgt5hy9 294 3 can can MD cord-280571-ntgt5hy9 294 4 we -PRON- PRP cord-280571-ntgt5hy9 294 5 test test VB cord-280571-ntgt5hy9 294 6 a a DT cord-280571-ntgt5hy9 294 7 test test NN cord-280571-ntgt5hy9 294 8 ? ? . cord-280571-ntgt5hy9 295 1 I -PRON- PRP cord-280571-ntgt5hy9 295 2 sincerely sincerely RB cord-280571-ntgt5hy9 295 3 thank thank VBP cord-280571-ntgt5hy9 295 4 the the DT cord-280571-ntgt5hy9 295 5 FDA FDA NNP cord-280571-ntgt5hy9 295 6 and and CC cord-280571-ntgt5hy9 295 7 the the DT cord-280571-ntgt5hy9 295 8 Infectious Infectious NNP cord-280571-ntgt5hy9 295 9 Diseases Diseases NNPS cord-280571-ntgt5hy9 295 10 Society Society NNP cord-280571-ntgt5hy9 295 11 of of IN cord-280571-ntgt5hy9 295 12 America America NNP cord-280571-ntgt5hy9 295 13 for for IN cord-280571-ntgt5hy9 295 14 providing provide VBG cord-280571-ntgt5hy9 295 15 a a DT cord-280571-ntgt5hy9 295 16 forum forum NN cord-280571-ntgt5hy9 295 17 for for IN cord-280571-ntgt5hy9 295 18 discussion discussion NN cord-280571-ntgt5hy9 295 19 and and CC cord-280571-ntgt5hy9 295 20 exchange exchange NN cord-280571-ntgt5hy9 295 21 of of IN cord-280571-ntgt5hy9 295 22 ideas idea NNS cord-280571-ntgt5hy9 295 23 relating relate VBG cord-280571-ntgt5hy9 295 24 to to IN cord-280571-ntgt5hy9 295 25 this this DT cord-280571-ntgt5hy9 295 26 timely timely JJ cord-280571-ntgt5hy9 295 27 and and CC cord-280571-ntgt5hy9 295 28 clinically clinically RB cord-280571-ntgt5hy9 295 29 relevant relevant JJ cord-280571-ntgt5hy9 295 30 topic topic NN cord-280571-ntgt5hy9 295 31 . . . cord-280571-ntgt5hy9 296 1 Financial financial JJ cord-280571-ntgt5hy9 296 2 support support NN cord-280571-ntgt5hy9 296 3 . . . cord-280571-ntgt5hy9 297 1 This this DT cord-280571-ntgt5hy9 297 2 work work NN cord-280571-ntgt5hy9 297 3 was be VBD cord-280571-ntgt5hy9 297 4 supported support VBN cord-280571-ntgt5hy9 297 5 by by IN cord-280571-ntgt5hy9 297 6 US US NNP cord-280571-ntgt5hy9 297 7 Department Department NNP cord-280571-ntgt5hy9 297 8 of of IN cord-280571-ntgt5hy9 297 9 Defense Defense NNP cord-280571-ntgt5hy9 297 10 Award Award NNP cord-280571-ntgt5hy9 297 11 W81XWH-08 W81XWH-08 NNP cord-280571-ntgt5hy9 297 12 - - HYPH cord-280571-ntgt5hy9 297 13 1 1 CD cord-280571-ntgt5hy9 297 14 - - HYPH cord-280571-ntgt5hy9 297 15 0477 0477 CD cord-280571-ntgt5hy9 297 16 . . . cord-280571-ntgt5hy9 298 1 Potential potential JJ cord-280571-ntgt5hy9 298 2 conflicts conflict NNS cord-280571-ntgt5hy9 298 3 of of IN cord-280571-ntgt5hy9 298 4 interest interest NN cord-280571-ntgt5hy9 298 5 . . . cord-280571-ntgt5hy9 299 1 C. C. NNP cord-280571-ntgt5hy9 299 2 C. C. NNP cord-280571-ntgt5hy9 299 3 G. G. NNP cord-280571-ntgt5hy9 299 4 is be VBZ cord-280571-ntgt5hy9 299 5 a a DT cord-280571-ntgt5hy9 299 6 member member NN cord-280571-ntgt5hy9 299 7 of of IN cord-280571-ntgt5hy9 299 8 the the DT cord-280571-ntgt5hy9 299 9 Scientific Scientific NNP cord-280571-ntgt5hy9 299 10 Advisory Advisory NNP cord-280571-ntgt5hy9 299 11 Boards Boards NNPS cord-280571-ntgt5hy9 299 12 of of IN cord-280571-ntgt5hy9 299 13 Gen Gen NNP cord-280571-ntgt5hy9 299 14 - - HYPH cord-280571-ntgt5hy9 299 15 Probe Probe NNP cord-280571-ntgt5hy9 299 16 / / SYM cord-280571-ntgt5hy9 299 17 Prodesse Prodesse NNP cord-280571-ntgt5hy9 299 18 and and CC cord-280571-ntgt5hy9 299 19 Luminex Luminex NNP cord-280571-ntgt5hy9 299 20 Molecular Molecular NNP cord-280571-ntgt5hy9 299 21 Diagnostics Diagnostics NNPS cord-280571-ntgt5hy9 299 22 . . . cord-280571-ntgt5hy9 300 1 C. C. NNP cord-280571-ntgt5hy9 300 2 C. C. NNP cord-280571-ntgt5hy9 300 3 G. G. NNP cord-280571-ntgt5hy9 300 4 has have VBZ cord-280571-ntgt5hy9 300 5 received receive VBN cord-280571-ntgt5hy9 300 6 research research NN cord-280571-ntgt5hy9 300 7 grants grant NNS cord-280571-ntgt5hy9 300 8 and and CC cord-280571-ntgt5hy9 300 9 honoraria honorarium NNS cord-280571-ntgt5hy9 300 10 from from IN cord-280571-ntgt5hy9 300 11 Gen Gen NNP cord-280571-ntgt5hy9 300 12 - - HYPH cord-280571-ntgt5hy9 300 13 Probe Probe NNP cord-280571-ntgt5hy9 300 14 / / SYM cord-280571-ntgt5hy9 300 15 Prodesse Prodesse NNP cord-280571-ntgt5hy9 300 16 , , , cord-280571-ntgt5hy9 300 17 Luminex Luminex NNP cord-280571-ntgt5hy9 300 18 Molecular Molecular NNP cord-280571-ntgt5hy9 300 19 Diagnostics Diagnostics NNPS cord-280571-ntgt5hy9 300 20 , , , cord-280571-ntgt5hy9 300 21 and and CC cord-280571-ntgt5hy9 300 22 Diagnostic Diagnostic NNP cord-280571-ntgt5hy9 300 23 Hybrids Hybrids NNPS cord-280571-ntgt5hy9 300 24 and and CC cord-280571-ntgt5hy9 300 25 research research NN cord-280571-ntgt5hy9 300 26 grants grant NNS cord-280571-ntgt5hy9 300 27 from from IN cord-280571-ntgt5hy9 300 28 3 3 CD cord-280571-ntgt5hy9 300 29 M M NNP cord-280571-ntgt5hy9 300 30 Molecular Molecular NNP cord-280571-ntgt5hy9 300 31 Diagnostics Diagnostics NNPS cord-280571-ntgt5hy9 300 32 and and CC cord-280571-ntgt5hy9 300 33 has have VBZ cord-280571-ntgt5hy9 300 34 been be VBN cord-280571-ntgt5hy9 300 35 a a DT cord-280571-ntgt5hy9 300 36 consultant consultant NN cord-280571-ntgt5hy9 300 37 for for IN cord-280571-ntgt5hy9 300 38 Nanosphere Nanosphere NNP cord-280571-ntgt5hy9 300 39 . . .