id author title date pages extension mime words sentences flesch summary cache txt cord-327352-cbnjsrmt Kipar, A Cellular composition, coronavirus antigen expression and production of specific antibodies in lesions in feline infectious peritonitis 1998-10-23 .txt text/plain 4923 263 38 Diffuse alterations on serosal surfaces were represented either by activated mesothelial cells with single coronavirus antigen-bearing macrophages or by layers of precipitated exudate containing single to numerous granulomas with areas of necrosis. Single plasma-cells positive for coronavirus-specific antibodies were found around blood vessels distant from inflammatory alterations, within the lung parenchyma, as infiltrating cells in the mucosa of the small intestine, and in spleen and mesenteric lymph node. Based on immunohistological and histochemical characterization of inflammatory cells as well as the presence of coronavirus antigen and plasma-cells producing coronavirus-specific antibodies in the lesions of 23 cats with spontaneous FIP, this study describes the composition of alterations observed in FIP after natural infection. Viral antigen was moderately expressed in granulomas, in the periphery of which few plasma-cells producing coronavirus-specific antibodies were seen. ./cache/cord-327352-cbnjsrmt.txt ./txt/cord-327352-cbnjsrmt.txt