id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-292570-618bt2vh	Shuid, Ahmad Naqib	Apoptosis transcriptional mechanism of feline infectious peritonitis virus infected cells	2015-09-19		.txt	text/plain	5657	308	49	Based on bioinformatics analysis, five deregulated genes of the apoptosis cluster were chosen for further analysis; namely, Ras association (RalGDS/AF-6) domain family member 1 (RASSF1), Basic Leucine Zipper Transcriptional Factor ATF-Like 2 (BATF2), Melanoma antigen family B 16 (MAGEB16), Programmed cell death 5 (PDCD5) and TNF receptor-associated factor 2 (TRAF2). Although TNFa did not show significant deregulation at 9 hpi using RNA-seq analysis, the number of related affected genes including significant up regulation of FADD, TRADD, TRAF2, Tumor necrosis factor induced protein 1 and 3 (TNFAIP1 and TNFAIP3) show the importance of analysis of this cytokine during apoptosis mechanism of FIPV. After investigation of the trend of apoptosis and expression change of selected genes from apoptosis cluster, the TNF receptor-associated factor 2 (TRAF2) and programmed cell death-5 (PDCD5) were the only genes that showed significant up regulation from the first hour after infection (Fig. 3) .	./cache/cord-292570-618bt2vh.txt	./txt/cord-292570-618bt2vh.txt