id sid tid token lemma pos cord-015569-vy49r1zd 1 1 key key NN cord-015569-vy49r1zd 1 2 : : : cord-015569-vy49r1zd 1 3 cord-015569-vy49r1zd cord-015569-vy49r1zd NN cord-015569-vy49r1zd 1 4 authors author NNS cord-015569-vy49r1zd 1 5 : : : cord-015569-vy49r1zd 2 1 nan nan NNP cord-015569-vy49r1zd 2 2 title title NN cord-015569-vy49r1zd 2 3 : : : cord-015569-vy49r1zd 2 4 Abstracts abstract NNS cord-015569-vy49r1zd 2 5 from from IN cord-015569-vy49r1zd 2 6 the the DT cord-015569-vy49r1zd 2 7 45(th 45(th CD cord-015569-vy49r1zd 2 8 ) ) -RRB- cord-015569-vy49r1zd 3 1 Annual annual JJ cord-015569-vy49r1zd 3 2 Meeting Meeting NNP cord-015569-vy49r1zd 3 3 of of IN cord-015569-vy49r1zd 3 4 Japanese Japanese NNP cord-015569-vy49r1zd 3 5 Association Association NNP cord-015569-vy49r1zd 3 6 for for IN cord-015569-vy49r1zd 3 7 the the DT cord-015569-vy49r1zd 3 8 Stusy Stusy NNP cord-015569-vy49r1zd 3 9 of of IN cord-015569-vy49r1zd 3 10 Taste Taste NNP cord-015569-vy49r1zd 3 11 and and CC cord-015569-vy49r1zd 3 12 Smell Smell NNP cord-015569-vy49r1zd 3 13 ( ( -LRB- cord-015569-vy49r1zd 3 14 JASTS JASTS NNP cord-015569-vy49r1zd 3 15 2011 2011 CD cord-015569-vy49r1zd 3 16 ) ) -RRB- cord-015569-vy49r1zd 4 1 , , , cord-015569-vy49r1zd 4 2 Kanazawa Kanazawa NNP cord-015569-vy49r1zd 4 3 , , , cord-015569-vy49r1zd 4 4 Japan Japan NNP cord-015569-vy49r1zd 4 5 , , , cord-015569-vy49r1zd 4 6 October October NNP cord-015569-vy49r1zd 4 7 5 5 CD cord-015569-vy49r1zd 4 8 - - HYPH cord-015569-vy49r1zd 4 9 7(th 7(th CD cord-015569-vy49r1zd 4 10 ) ) -RRB- cord-015569-vy49r1zd 4 11 , , , cord-015569-vy49r1zd 4 12 2011 2011 CD cord-015569-vy49r1zd 5 1 ( ( -LRB- cord-015569-vy49r1zd 5 2 The the DT cord-015569-vy49r1zd 5 3 president president NN cord-015569-vy49r1zd 5 4 of of IN cord-015569-vy49r1zd 5 5 the the DT cord-015569-vy49r1zd 5 6 meeting meeting NN cord-015569-vy49r1zd 5 7 was be VBD cord-015569-vy49r1zd 5 8 Dr. Dr. NNP cord-015569-vy49r1zd 5 9 Takaki Takaki NNP cord-015569-vy49r1zd 5 10 Miwa Miwa NNP cord-015569-vy49r1zd 5 11 , , , cord-015569-vy49r1zd 5 12 Kanazawa Kanazawa NNP cord-015569-vy49r1zd 5 13 Medical Medical NNP cord-015569-vy49r1zd 5 14 University University NNP cord-015569-vy49r1zd 5 15 ) ) -RRB- cord-015569-vy49r1zd 5 16 date date NN cord-015569-vy49r1zd 5 17 : : : cord-015569-vy49r1zd 5 18 2012 2012 CD cord-015569-vy49r1zd 5 19 - - HYPH cord-015569-vy49r1zd 5 20 05 05 CD cord-015569-vy49r1zd 5 21 - - SYM cord-015569-vy49r1zd 5 22 17 17 CD cord-015569-vy49r1zd 5 23 journal journal NN cord-015569-vy49r1zd 5 24 : : : cord-015569-vy49r1zd 6 1 Chem Chem NNP cord-015569-vy49r1zd 6 2 Senses Senses NNP cord-015569-vy49r1zd 6 3 DOI DOI NNP cord-015569-vy49r1zd 6 4 : : : cord-015569-vy49r1zd 6 5 10.1093 10.1093 CD cord-015569-vy49r1zd 6 6 / / SYM cord-015569-vy49r1zd 6 7 chemse chemse NNP cord-015569-vy49r1zd 6 8 / / SYM cord-015569-vy49r1zd 6 9 bjs052 bjs052 NNP cord-015569-vy49r1zd 6 10 sha sha NNP cord-015569-vy49r1zd 6 11 : : : cord-015569-vy49r1zd 7 1 c82b4dfc17c0221eeb08886c6f1d015f27028760 c82b4dfc17c0221eeb08886c6f1d015f27028760 NNP cord-015569-vy49r1zd 7 2 doc_id doc_id CD cord-015569-vy49r1zd 7 3 : : : cord-015569-vy49r1zd 7 4 15569 15569 CD cord-015569-vy49r1zd 7 5 cord_uid cord_uid FW cord-015569-vy49r1zd 7 6 : : : cord-015569-vy49r1zd 8 1 vy49r1zd vy49r1zd NNP cord-015569-vy49r1zd 8 2 nan nan NNP cord-015569-vy49r1zd 9 1 Since since IN cord-015569-vy49r1zd 9 2 umami umami NN cord-015569-vy49r1zd 9 3 taste taste NN cord-015569-vy49r1zd 9 4 receptors receptor NNS cord-015569-vy49r1zd 9 5 T1R1 T1R1 NNP cord-015569-vy49r1zd 9 6 and and CC cord-015569-vy49r1zd 9 7 T1R3 T1R3 NNP cord-015569-vy49r1zd 9 8 have have VBP cord-015569-vy49r1zd 9 9 been be VBN cord-015569-vy49r1zd 9 10 identified identify VBN cord-015569-vy49r1zd 9 11 , , , cord-015569-vy49r1zd 9 12 some some DT cord-015569-vy49r1zd 9 13 reports report NNS cord-015569-vy49r1zd 9 14 revealed reveal VBD cord-015569-vy49r1zd 9 15 their -PRON- PRP$ cord-015569-vy49r1zd 9 16 structures structure NNS cord-015569-vy49r1zd 9 17 and and CC cord-015569-vy49r1zd 9 18 functions function NNS cord-015569-vy49r1zd 9 19 . . . cord-015569-vy49r1zd 10 1 Umami Umami VBG cord-015569-vy49r1zd 10 2 taste taste VBP cord-015569-vy49r1zd 10 3 receptors receptor NNS cord-015569-vy49r1zd 10 4 are be VBP cord-015569-vy49r1zd 10 5 member member NN cord-015569-vy49r1zd 10 6 of of IN cord-015569-vy49r1zd 10 7 G G NNP cord-015569-vy49r1zd 10 8 protein protein NN cord-015569-vy49r1zd 10 9 - - HYPH cord-015569-vy49r1zd 10 10 coupled couple VBN cord-015569-vy49r1zd 10 11 receptors receptor NNS cord-015569-vy49r1zd 10 12 , , , cord-015569-vy49r1zd 10 13 belonging belong VBG cord-015569-vy49r1zd 10 14 to to IN cord-015569-vy49r1zd 10 15 family family NN cord-015569-vy49r1zd 10 16 C C NNP cord-015569-vy49r1zd 10 17 with with IN cord-015569-vy49r1zd 10 18 long long JJ cord-015569-vy49r1zd 10 19 N n CD cord-015569-vy49r1zd 10 20 - - HYPH cord-015569-vy49r1zd 10 21 terminal terminal NN cord-015569-vy49r1zd 10 22 extracellular extracellular JJ cord-015569-vy49r1zd 10 23 domain domain NN cord-015569-vy49r1zd 10 24 . . . cord-015569-vy49r1zd 11 1 T1R1 T1R1 NNP cord-015569-vy49r1zd 11 2 and and CC cord-015569-vy49r1zd 11 3 T1R3 T1R3 NNP cord-015569-vy49r1zd 11 4 percept percept NNP cord-015569-vy49r1zd 11 5 umami umami JJ cord-015569-vy49r1zd 11 6 taste taste NN cord-015569-vy49r1zd 11 7 as as IN cord-015569-vy49r1zd 11 8 a a DT cord-015569-vy49r1zd 11 9 heterodimer heterodimer NN cord-015569-vy49r1zd 11 10 . . . cord-015569-vy49r1zd 12 1 We -PRON- PRP cord-015569-vy49r1zd 12 2 focused focus VBD cord-015569-vy49r1zd 12 3 on on IN cord-015569-vy49r1zd 12 4 leucine leucine NN cord-015569-vy49r1zd 12 5 repeats repeat NNS cord-015569-vy49r1zd 12 6 of of IN cord-015569-vy49r1zd 12 7 T1R1 T1R1 NNP cord-015569-vy49r1zd 12 8 and and CC cord-015569-vy49r1zd 12 9 T1R3 T1R3 NNP cord-015569-vy49r1zd 12 10 in in IN cord-015569-vy49r1zd 12 11 their -PRON- PRP$ cord-015569-vy49r1zd 12 12 transmembrane transmembrane NN cord-015569-vy49r1zd 12 13 domains domain NNS cord-015569-vy49r1zd 12 14 . . . cord-015569-vy49r1zd 13 1 We -PRON- PRP cord-015569-vy49r1zd 13 2 have have VBP cord-015569-vy49r1zd 13 3 reported report VBN cord-015569-vy49r1zd 13 4 the the DT cord-015569-vy49r1zd 13 5 possibility possibility NN cord-015569-vy49r1zd 13 6 of of IN cord-015569-vy49r1zd 13 7 correlation correlation NN cord-015569-vy49r1zd 13 8 between between IN cord-015569-vy49r1zd 13 9 the the DT cord-015569-vy49r1zd 13 10 food food NN cord-015569-vy49r1zd 13 11 preference preference NN cord-015569-vy49r1zd 13 12 of of IN cord-015569-vy49r1zd 13 13 animals animal NNS cord-015569-vy49r1zd 13 14 and and CC cord-015569-vy49r1zd 13 15 difference difference NN cord-015569-vy49r1zd 13 16 in in IN cord-015569-vy49r1zd 13 17 the the DT cord-015569-vy49r1zd 13 18 length length NN cord-015569-vy49r1zd 13 19 of of IN cord-015569-vy49r1zd 13 20 leucine leucine NN cord-015569-vy49r1zd 13 21 repeats repeat VBZ cord-015569-vy49r1zd 13 22 . . . cord-015569-vy49r1zd 14 1 Poly poly JJ cord-015569-vy49r1zd 14 2 leucine leucine NN cord-015569-vy49r1zd 14 3 ( ( -LRB- cord-015569-vy49r1zd 14 4 polyL polyL NNP cord-015569-vy49r1zd 14 5 ) ) -RRB- cord-015569-vy49r1zd 14 6 is be VBZ cord-015569-vy49r1zd 14 7 called call VBN cord-015569-vy49r1zd 14 8 homo homo JJ cord-015569-vy49r1zd 14 9 polymeric polymeric JJ cord-015569-vy49r1zd 14 10 amino amino NN cord-015569-vy49r1zd 14 11 acid acid NN cord-015569-vy49r1zd 14 12 , , , cord-015569-vy49r1zd 14 13 so so RB cord-015569-vy49r1zd 14 14 called call VBN cord-015569-vy49r1zd 14 15 HPAA HPAA NNP cord-015569-vy49r1zd 14 16 . . . cord-015569-vy49r1zd 15 1 It -PRON- PRP cord-015569-vy49r1zd 15 2 is be VBZ cord-015569-vy49r1zd 15 3 reported report VBN cord-015569-vy49r1zd 15 4 that that IN cord-015569-vy49r1zd 15 5 1;2 1;2 CD cord-015569-vy49r1zd 15 6 % % NN cord-015569-vy49r1zd 15 7 of of IN cord-015569-vy49r1zd 15 8 proteins protein NNS cord-015569-vy49r1zd 15 9 in in IN cord-015569-vy49r1zd 15 10 prokaryotic prokaryotic JJ cord-015569-vy49r1zd 15 11 and and CC cord-015569-vy49r1zd 15 12 eukaryotic eukaryotic JJ cord-015569-vy49r1zd 15 13 organisms organism NNS cord-015569-vy49r1zd 15 14 contain contain VBP cord-015569-vy49r1zd 15 15 HPAAs hpaa NNS cord-015569-vy49r1zd 15 16 . . . cord-015569-vy49r1zd 16 1 It -PRON- PRP cord-015569-vy49r1zd 16 2 is be VBZ cord-015569-vy49r1zd 16 3 also also RB cord-015569-vy49r1zd 16 4 suggested suggest VBN cord-015569-vy49r1zd 16 5 that that IN cord-015569-vy49r1zd 16 6 polyL polyL NNP cord-015569-vy49r1zd 16 7 could could MD cord-015569-vy49r1zd 16 8 interact interact VB cord-015569-vy49r1zd 16 9 with with IN cord-015569-vy49r1zd 16 10 each each DT cord-015569-vy49r1zd 16 11 other other JJ cord-015569-vy49r1zd 16 12 more more JJR cord-015569-vy49r1zd 16 13 than than IN cord-015569-vy49r1zd 16 14 with with IN cord-015569-vy49r1zd 16 15 the the DT cord-015569-vy49r1zd 16 16 other other JJ cord-015569-vy49r1zd 16 17 HPAAs hpaa NNS cord-015569-vy49r1zd 16 18 . . . cord-015569-vy49r1zd 17 1 Some some DT cord-015569-vy49r1zd 17 2 inherited inherit VBN cord-015569-vy49r1zd 17 3 diseases disease NNS cord-015569-vy49r1zd 17 4 are be VBP cord-015569-vy49r1zd 17 5 caused cause VBN cord-015569-vy49r1zd 17 6 by by IN cord-015569-vy49r1zd 17 7 proteins protein NNS cord-015569-vy49r1zd 17 8 in in IN cord-015569-vy49r1zd 17 9 which which WDT cord-015569-vy49r1zd 17 10 HPAAs hpaa NNS cord-015569-vy49r1zd 17 11 such such JJ cord-015569-vy49r1zd 17 12 as as IN cord-015569-vy49r1zd 17 13 polyQ polyQ NNP cord-015569-vy49r1zd 17 14 , , , cord-015569-vy49r1zd 17 15 polyA polyA NNP cord-015569-vy49r1zd 17 16 are be VBP cord-015569-vy49r1zd 17 17 expanded expand VBN cord-015569-vy49r1zd 17 18 to to IN cord-015569-vy49r1zd 17 19 excessive excessive JJ cord-015569-vy49r1zd 17 20 length length NN cord-015569-vy49r1zd 17 21 . . . cord-015569-vy49r1zd 18 1 Activity activity NN cord-015569-vy49r1zd 18 2 of of IN cord-015569-vy49r1zd 18 3 the the DT cord-015569-vy49r1zd 18 4 protein protein NN cord-015569-vy49r1zd 18 5 containing contain VBG cord-015569-vy49r1zd 18 6 HPAAs HPAAs NNP cord-015569-vy49r1zd 18 7 is be VBZ cord-015569-vy49r1zd 18 8 thought think VBN cord-015569-vy49r1zd 18 9 to to TO cord-015569-vy49r1zd 18 10 be be VB cord-015569-vy49r1zd 18 11 increased increase VBN cord-015569-vy49r1zd 18 12 by by IN cord-015569-vy49r1zd 18 13 expansion expansion NN cord-015569-vy49r1zd 18 14 of of IN cord-015569-vy49r1zd 18 15 HPAAs hpaa NNS cord-015569-vy49r1zd 18 16 , , , cord-015569-vy49r1zd 18 17 but but CC cord-015569-vy49r1zd 18 18 with with IN cord-015569-vy49r1zd 18 19 expansion expansion NN cord-015569-vy49r1zd 18 20 of of IN cord-015569-vy49r1zd 18 21 more more JJR cord-015569-vy49r1zd 18 22 than than IN cord-015569-vy49r1zd 18 23 the the DT cord-015569-vy49r1zd 18 24 threshold threshold NN cord-015569-vy49r1zd 18 25 , , , cord-015569-vy49r1zd 18 26 activity activity NN cord-015569-vy49r1zd 18 27 of of IN cord-015569-vy49r1zd 18 28 the the DT cord-015569-vy49r1zd 18 29 protein protein NN cord-015569-vy49r1zd 18 30 is be VBZ cord-015569-vy49r1zd 18 31 suddenly suddenly RB cord-015569-vy49r1zd 18 32 decreased decrease VBN cord-015569-vy49r1zd 18 33 . . . cord-015569-vy49r1zd 19 1 HPAAs hpaa NNS cord-015569-vy49r1zd 19 2 are be VBP cord-015569-vy49r1zd 19 3 one one CD cord-015569-vy49r1zd 19 4 of of IN cord-015569-vy49r1zd 19 5 the the DT cord-015569-vy49r1zd 19 6 structures structure NNS cord-015569-vy49r1zd 19 7 to to TO cord-015569-vy49r1zd 19 8 be be VB cord-015569-vy49r1zd 19 9 seen see VBN cord-015569-vy49r1zd 19 10 frequently frequently RB cord-015569-vy49r1zd 19 11 . . . cord-015569-vy49r1zd 20 1 It -PRON- PRP cord-015569-vy49r1zd 20 2 is be VBZ cord-015569-vy49r1zd 20 3 suggested suggest VBN cord-015569-vy49r1zd 20 4 that that IN cord-015569-vy49r1zd 20 5 HPAAs hpaa NNS cord-015569-vy49r1zd 20 6 are be VBP cord-015569-vy49r1zd 20 7 important important JJ cord-015569-vy49r1zd 20 8 structures structure NNS cord-015569-vy49r1zd 20 9 for for IN cord-015569-vy49r1zd 20 10 some some DT cord-015569-vy49r1zd 20 11 proteins protein NNS cord-015569-vy49r1zd 20 12 to to TO cord-015569-vy49r1zd 20 13 function function VB cord-015569-vy49r1zd 20 14 . . . cord-015569-vy49r1zd 21 1 On on IN cord-015569-vy49r1zd 21 2 the the DT cord-015569-vy49r1zd 21 3 other other JJ cord-015569-vy49r1zd 21 4 hand hand NN cord-015569-vy49r1zd 21 5 normal normal JJ cord-015569-vy49r1zd 21 6 function function NN cord-015569-vy49r1zd 21 7 of of IN cord-015569-vy49r1zd 21 8 HPAAs HPAAs NNP cord-015569-vy49r1zd 21 9 remains remain VBZ cord-015569-vy49r1zd 21 10 unclear unclear JJ cord-015569-vy49r1zd 21 11 . . . cord-015569-vy49r1zd 22 1 From from IN cord-015569-vy49r1zd 22 2 the the DT cord-015569-vy49r1zd 22 3 above above JJ cord-015569-vy49r1zd 22 4 point point NN cord-015569-vy49r1zd 22 5 of of IN cord-015569-vy49r1zd 22 6 view view NN cord-015569-vy49r1zd 22 7 , , , cord-015569-vy49r1zd 22 8 polyL polyL NNP cord-015569-vy49r1zd 22 9 might may MD cord-015569-vy49r1zd 22 10 affect affect VB cord-015569-vy49r1zd 22 11 interaction interaction NN cord-015569-vy49r1zd 22 12 of of IN cord-015569-vy49r1zd 22 13 umami umami NN cord-015569-vy49r1zd 22 14 taste taste NN cord-015569-vy49r1zd 22 15 receptor receptor NN cord-015569-vy49r1zd 22 16 T1R1 T1R1 NNP cord-015569-vy49r1zd 22 17 and and CC cord-015569-vy49r1zd 22 18 T1R3 T1R3 NNP cord-015569-vy49r1zd 22 19 . . . cord-015569-vy49r1zd 23 1 We -PRON- PRP cord-015569-vy49r1zd 23 2 also also RB cord-015569-vy49r1zd 23 3 hypothesize hypothesize VBP cord-015569-vy49r1zd 23 4 polyL polyL NNP cord-015569-vy49r1zd 23 5 play play VB cord-015569-vy49r1zd 23 6 an an DT cord-015569-vy49r1zd 23 7 important important JJ cord-015569-vy49r1zd 23 8 role role NN cord-015569-vy49r1zd 23 9 in in IN cord-015569-vy49r1zd 23 10 the the DT cord-015569-vy49r1zd 23 11 perception perception NN cord-015569-vy49r1zd 23 12 of of IN cord-015569-vy49r1zd 23 13 umami umami NN cord-015569-vy49r1zd 23 14 . . . cord-015569-vy49r1zd 24 1 Some some DT cord-015569-vy49r1zd 24 2 odorant odorant NN cord-015569-vy49r1zd 24 3 receptors receptor NNS cord-015569-vy49r1zd 24 4 also also RB cord-015569-vy49r1zd 24 5 have have VBP cord-015569-vy49r1zd 24 6 the the DT cord-015569-vy49r1zd 24 7 similar similar JJ cord-015569-vy49r1zd 24 8 polyL polyL NNP cord-015569-vy49r1zd 24 9 structure structure NN cord-015569-vy49r1zd 24 10 , , , cord-015569-vy49r1zd 24 11 suggesting suggest VBG cord-015569-vy49r1zd 24 12 that that IN cord-015569-vy49r1zd 24 13 under under IN cord-015569-vy49r1zd 24 14 the the DT cord-015569-vy49r1zd 24 15 hydrophobic hydrophobic JJ cord-015569-vy49r1zd 24 16 condition condition NN cord-015569-vy49r1zd 24 17 some some DT cord-015569-vy49r1zd 24 18 proteins protein NNS cord-015569-vy49r1zd 24 19 are be VBP cord-015569-vy49r1zd 24 20 dimerized dimerize VBN cord-015569-vy49r1zd 24 21 by by IN cord-015569-vy49r1zd 24 22 interactions interaction NNS cord-015569-vy49r1zd 24 23 between between IN cord-015569-vy49r1zd 24 24 leucine leucine NN cord-015569-vy49r1zd 24 25 repeats repeat VBZ cord-015569-vy49r1zd 24 26 . . . cord-015569-vy49r1zd 25 1 We -PRON- PRP cord-015569-vy49r1zd 25 2 named name VBD cord-015569-vy49r1zd 25 3 a a DT cord-015569-vy49r1zd 25 4 leucine leucine NN cord-015569-vy49r1zd 25 5 HPAAs hpaas NN cord-015569-vy49r1zd 25 6 motif motif NN cord-015569-vy49r1zd 25 7 for for IN cord-015569-vy49r1zd 25 8 protein protein NN cord-015569-vy49r1zd 25 9 - - HYPH cord-015569-vy49r1zd 25 10 protein protein NN cord-015569-vy49r1zd 25 11 interaction interaction NN cord-015569-vy49r1zd 25 12 as as IN cord-015569-vy49r1zd 25 13 ' ' '' cord-015569-vy49r1zd 25 14 ' ' `` cord-015569-vy49r1zd 25 15 Leucine Leucine NNP cord-015569-vy49r1zd 25 16 Glue Glue NNP cord-015569-vy49r1zd 25 17 . . . cord-015569-vy49r1zd 25 18 ' ' '' cord-015569-vy49r1zd 25 19 ' ' '' cord-015569-vy49r1zd 26 1 We -PRON- PRP cord-015569-vy49r1zd 26 2 are be VBP cord-015569-vy49r1zd 26 3 discussing discuss VBG cord-015569-vy49r1zd 26 4 the the DT cord-015569-vy49r1zd 26 5 effect effect NN cord-015569-vy49r1zd 26 6 of of IN cord-015569-vy49r1zd 26 7 polyL polyL NNP cord-015569-vy49r1zd 26 8 on on IN cord-015569-vy49r1zd 26 9 protein protein NN cord-015569-vy49r1zd 26 10 - - HYPH cord-015569-vy49r1zd 26 11 protein protein NN cord-015569-vy49r1zd 26 12 interaction interaction NN cord-015569-vy49r1zd 26 13 by by IN cord-015569-vy49r1zd 26 14 using use VBG cord-015569-vy49r1zd 26 15 Split Split NNP cord-015569-vy49r1zd 26 16 GFP GFP NNP cord-015569-vy49r1zd 26 17 assay assay NN cord-015569-vy49r1zd 26 18 . . . cord-015569-vy49r1zd 27 1 # # $ cord-015569-vy49r1zd 27 2 3 3 CD cord-015569-vy49r1zd 27 3 Comparative comparative JJ cord-015569-vy49r1zd 27 4 analysis analysis NN cord-015569-vy49r1zd 27 5 of of IN cord-015569-vy49r1zd 27 6 the the DT cord-015569-vy49r1zd 27 7 umami umami NN cord-015569-vy49r1zd 27 8 receptor receptor NN cord-015569-vy49r1zd 27 9 gene gene NN cord-015569-vy49r1zd 27 10 , , , cord-015569-vy49r1zd 27 11 t1r1 t1r1 NN cord-015569-vy49r1zd 27 12 from from IN cord-015569-vy49r1zd 27 13 Cetaceans Cetaceans NNP cord-015569-vy49r1zd 27 14 T1R1 T1R1 NNP cord-015569-vy49r1zd 27 15 and and CC cord-015569-vy49r1zd 27 16 T1R3 T1R3 NNP cord-015569-vy49r1zd 27 17 are be VBP cord-015569-vy49r1zd 27 18 known know VBN cord-015569-vy49r1zd 27 19 to to TO cord-015569-vy49r1zd 27 20 act act VB cord-015569-vy49r1zd 27 21 as as IN cord-015569-vy49r1zd 27 22 umami umami NN cord-015569-vy49r1zd 27 23 receptor receptor NN cord-015569-vy49r1zd 27 24 . . . cord-015569-vy49r1zd 28 1 They -PRON- PRP cord-015569-vy49r1zd 28 2 are be VBP cord-015569-vy49r1zd 28 3 member member NN cord-015569-vy49r1zd 28 4 of of IN cord-015569-vy49r1zd 28 5 G G NNP cord-015569-vy49r1zd 28 6 protein protein NN cord-015569-vy49r1zd 28 7 - - HYPH cord-015569-vy49r1zd 28 8 coupled couple VBN cord-015569-vy49r1zd 28 9 receptors receptor NNS cord-015569-vy49r1zd 28 10 ( ( -LRB- cord-015569-vy49r1zd 28 11 GPCR GPCR NNP cord-015569-vy49r1zd 28 12 ) ) -RRB- cord-015569-vy49r1zd 28 13 and and CC cord-015569-vy49r1zd 28 14 have have VBP cord-015569-vy49r1zd 28 15 seven seven CD cord-015569-vy49r1zd 28 16 transmembrane transmembrane NN cord-015569-vy49r1zd 28 17 domains domain NNS cord-015569-vy49r1zd 28 18 . . . cord-015569-vy49r1zd 29 1 In in IN cord-015569-vy49r1zd 29 2 2010 2010 CD cord-015569-vy49r1zd 29 3 , , , cord-015569-vy49r1zd 29 4 it -PRON- PRP cord-015569-vy49r1zd 29 5 has have VBZ cord-015569-vy49r1zd 29 6 been be VBN cord-015569-vy49r1zd 29 7 reported report VBN cord-015569-vy49r1zd 29 8 that that IN cord-015569-vy49r1zd 29 9 the the DT cord-015569-vy49r1zd 29 10 t1r1 t1r1 NNP cord-015569-vy49r1zd 29 11 gene gene NN cord-015569-vy49r1zd 29 12 of of IN cord-015569-vy49r1zd 29 13 giant giant JJ cord-015569-vy49r1zd 29 14 panda panda NN cord-015569-vy49r1zd 29 15 has have VBZ cord-015569-vy49r1zd 29 16 frameshift frameshift NN cord-015569-vy49r1zd 29 17 mutation mutation NN cord-015569-vy49r1zd 29 18 , , , cord-015569-vy49r1zd 29 19 resulting result VBG cord-015569-vy49r1zd 29 20 in in IN cord-015569-vy49r1zd 29 21 inactivation inactivation NN cord-015569-vy49r1zd 29 22 of of IN cord-015569-vy49r1zd 29 23 umami umami NN cord-015569-vy49r1zd 29 24 receptor receptor NN cord-015569-vy49r1zd 29 25 . . . cord-015569-vy49r1zd 30 1 Originally originally RB cord-015569-vy49r1zd 30 2 , , , cord-015569-vy49r1zd 30 3 they -PRON- PRP cord-015569-vy49r1zd 30 4 are be VBP cord-015569-vy49r1zd 30 5 used use VBN cord-015569-vy49r1zd 30 6 to to TO cord-015569-vy49r1zd 30 7 be be VB cord-015569-vy49r1zd 30 8 a a DT cord-015569-vy49r1zd 30 9 carnivorous carnivorous JJ cord-015569-vy49r1zd 30 10 animal animal NN cord-015569-vy49r1zd 30 11 . . . cord-015569-vy49r1zd 31 1 It -PRON- PRP cord-015569-vy49r1zd 31 2 is be VBZ cord-015569-vy49r1zd 31 3 suggested suggest VBN cord-015569-vy49r1zd 31 4 that that IN cord-015569-vy49r1zd 31 5 the the DT cord-015569-vy49r1zd 31 6 mutation mutation NN cord-015569-vy49r1zd 31 7 of of IN cord-015569-vy49r1zd 31 8 the the DT cord-015569-vy49r1zd 31 9 t1r1 t1r1 NNP cord-015569-vy49r1zd 31 10 gene gene NN cord-015569-vy49r1zd 31 11 might may MD cord-015569-vy49r1zd 31 12 be be VB cord-015569-vy49r1zd 31 13 associated associate VBN cord-015569-vy49r1zd 31 14 with with IN cord-015569-vy49r1zd 31 15 their -PRON- PRP$ cord-015569-vy49r1zd 31 16 current current JJ cord-015569-vy49r1zd 31 17 food food NN cord-015569-vy49r1zd 31 18 preference preference NN cord-015569-vy49r1zd 31 19 . . . cord-015569-vy49r1zd 32 1 We -PRON- PRP cord-015569-vy49r1zd 32 2 have have VBP cord-015569-vy49r1zd 32 3 already already RB cord-015569-vy49r1zd 32 4 analyzed analyze VBN cord-015569-vy49r1zd 32 5 genomic genomic JJ cord-015569-vy49r1zd 32 6 sequences sequence NNS cord-015569-vy49r1zd 32 7 of of IN cord-015569-vy49r1zd 32 8 the the DT cord-015569-vy49r1zd 32 9 t1r1 t1r1 NNP cord-015569-vy49r1zd 32 10 genes gene NNS cord-015569-vy49r1zd 32 11 from from IN cord-015569-vy49r1zd 32 12 two two CD cord-015569-vy49r1zd 32 13 different different JJ cord-015569-vy49r1zd 32 14 dolphins dolphin NNS cord-015569-vy49r1zd 32 15 ; ; : cord-015569-vy49r1zd 32 16 Lagenorhynchus Lagenorhynchus NNP cord-015569-vy49r1zd 32 17 obliquidens obliquidens NNP cord-015569-vy49r1zd 32 18 and and CC cord-015569-vy49r1zd 32 19 Tursiops Tursiops NNP cord-015569-vy49r1zd 32 20 truncatus truncatus NN cord-015569-vy49r1zd 32 21 . . . cord-015569-vy49r1zd 33 1 The the DT cord-015569-vy49r1zd 33 2 results result NNS cord-015569-vy49r1zd 33 3 strongly strongly RB cord-015569-vy49r1zd 33 4 suggested suggest VBD cord-015569-vy49r1zd 33 5 that that IN cord-015569-vy49r1zd 33 6 umami umami NN cord-015569-vy49r1zd 33 7 receptor receptor NN cord-015569-vy49r1zd 33 8 genes gene NNS cord-015569-vy49r1zd 33 9 , , , cord-015569-vy49r1zd 33 10 t1r1 t1r1 VBD cord-015569-vy49r1zd 33 11 from from IN cord-015569-vy49r1zd 33 12 both both DT cord-015569-vy49r1zd 33 13 cetaceans cetacean NNS cord-015569-vy49r1zd 33 14 are be VBP cord-015569-vy49r1zd 33 15 not not RB cord-015569-vy49r1zd 33 16 functional functional JJ cord-015569-vy49r1zd 33 17 , , , cord-015569-vy49r1zd 33 18 because because IN cord-015569-vy49r1zd 33 19 frameshift frameshift NN cord-015569-vy49r1zd 33 20 mutations mutation NNS cord-015569-vy49r1zd 33 21 occurred occur VBD cord-015569-vy49r1zd 33 22 in in IN cord-015569-vy49r1zd 33 23 their -PRON- PRP$ cord-015569-vy49r1zd 33 24 coding coding NN cord-015569-vy49r1zd 33 25 sequences sequence NNS cord-015569-vy49r1zd 33 26 . . . cord-015569-vy49r1zd 34 1 Nonsense nonsense NN cord-015569-vy49r1zd 34 2 codon codon NN cord-015569-vy49r1zd 34 3 caused cause VBN cord-015569-vy49r1zd 34 4 by by IN cord-015569-vy49r1zd 34 5 these these DT cord-015569-vy49r1zd 34 6 framshift framshift NNP cord-015569-vy49r1zd 34 7 mutations mutation NNS cord-015569-vy49r1zd 34 8 appeared appear VBD cord-015569-vy49r1zd 34 9 on on IN cord-015569-vy49r1zd 34 10 their -PRON- PRP$ cord-015569-vy49r1zd 34 11 downstream downstream JJ cord-015569-vy49r1zd 34 12 region region NN cord-015569-vy49r1zd 34 13 . . . cord-015569-vy49r1zd 35 1 In in IN cord-015569-vy49r1zd 35 2 this this DT cord-015569-vy49r1zd 35 3 study study NN cord-015569-vy49r1zd 35 4 , , , cord-015569-vy49r1zd 35 5 we -PRON- PRP cord-015569-vy49r1zd 35 6 have have VBP cord-015569-vy49r1zd 35 7 also also RB cord-015569-vy49r1zd 35 8 cloned clone VBN cord-015569-vy49r1zd 35 9 two two CD cord-015569-vy49r1zd 35 10 more more JJR cord-015569-vy49r1zd 35 11 t1r1 t1r1 NN cord-015569-vy49r1zd 35 12 genes gene NNS cord-015569-vy49r1zd 35 13 from from IN cord-015569-vy49r1zd 35 14 cetaceans cetacean NNS cord-015569-vy49r1zd 35 15 , , , cord-015569-vy49r1zd 35 16 Balaenoptera Balaenoptera NNP cord-015569-vy49r1zd 35 17 acutorostrata acutorostrata VBZ cord-015569-vy49r1zd 35 18 and and CC cord-015569-vy49r1zd 35 19 Balaenoptera Balaenoptera NNP cord-015569-vy49r1zd 35 20 physalus physalus NNP cord-015569-vy49r1zd 35 21 . . . cord-015569-vy49r1zd 36 1 Both both DT cord-015569-vy49r1zd 36 2 the the DT cord-015569-vy49r1zd 36 3 t1r1 t1r1 NNP cord-015569-vy49r1zd 36 4 genes gene NNS cord-015569-vy49r1zd 36 5 had have VBD cord-015569-vy49r1zd 36 6 frameshift frameshift NN cord-015569-vy49r1zd 36 7 mutation mutation NN cord-015569-vy49r1zd 36 8 and and CC cord-015569-vy49r1zd 36 9 various various JJ cord-015569-vy49r1zd 36 10 mutations mutation NNS cord-015569-vy49r1zd 36 11 in in IN cord-015569-vy49r1zd 36 12 their -PRON- PRP$ cord-015569-vy49r1zd 36 13 coding coding NN cord-015569-vy49r1zd 36 14 sequences sequence NNS cord-015569-vy49r1zd 36 15 . . . cord-015569-vy49r1zd 37 1 In in IN cord-015569-vy49r1zd 37 2 addition addition NN cord-015569-vy49r1zd 37 3 , , , cord-015569-vy49r1zd 37 4 we -PRON- PRP cord-015569-vy49r1zd 37 5 have have VBP cord-015569-vy49r1zd 37 6 also also RB cord-015569-vy49r1zd 37 7 cloned clone VBN cord-015569-vy49r1zd 37 8 two two CD cord-015569-vy49r1zd 37 9 more more JJR cord-015569-vy49r1zd 37 10 t1r1 t1r1 NN cord-015569-vy49r1zd 37 11 genes gene NNS cord-015569-vy49r1zd 37 12 from from IN cord-015569-vy49r1zd 37 13 cetaceans cetacean NNS cord-015569-vy49r1zd 37 14 , , , cord-015569-vy49r1zd 37 15 B. B. NNP cord-015569-vy49r1zd 37 16 acutorostrata acutorostrata NN cord-015569-vy49r1zd 37 17 and and CC cord-015569-vy49r1zd 37 18 B. B. NNP cord-015569-vy49r1zd 37 19 Physalus Physalus NNP cord-015569-vy49r1zd 37 20 . . . cord-015569-vy49r1zd 38 1 Both both DT cord-015569-vy49r1zd 38 2 the the DT cord-015569-vy49r1zd 38 3 t1r1 t1r1 NNP cord-015569-vy49r1zd 38 4 genes gene NNS cord-015569-vy49r1zd 38 5 had have VBD cord-015569-vy49r1zd 38 6 frameshift frameshift NN cord-015569-vy49r1zd 38 7 mutations mutation NNS cord-015569-vy49r1zd 38 8 and and CC cord-015569-vy49r1zd 38 9 various various JJ cord-015569-vy49r1zd 38 10 mutations mutation NNS cord-015569-vy49r1zd 38 11 in in IN cord-015569-vy49r1zd 38 12 their -PRON- PRP$ cord-015569-vy49r1zd 38 13 coding coding NN cord-015569-vy49r1zd 38 14 sequences sequence NNS cord-015569-vy49r1zd 38 15 as as RB cord-015569-vy49r1zd 38 16 well well RB cord-015569-vy49r1zd 38 17 as as IN cord-015569-vy49r1zd 38 18 dolphins dolphin NNS cord-015569-vy49r1zd 38 19 described describe VBN cord-015569-vy49r1zd 38 20 above above RB cord-015569-vy49r1zd 38 21 . . . cord-015569-vy49r1zd 39 1 Especially especially RB cord-015569-vy49r1zd 39 2 , , , cord-015569-vy49r1zd 39 3 in in IN cord-015569-vy49r1zd 39 4 one one CD cord-015569-vy49r1zd 39 5 allele allele NN cord-015569-vy49r1zd 39 6 from from IN cord-015569-vy49r1zd 39 7 both both CC cord-015569-vy49r1zd 39 8 B. B. NNP cord-015569-vy49r1zd 39 9 acutorostrata acutorostrata NN cord-015569-vy49r1zd 39 10 and and CC cord-015569-vy49r1zd 39 11 B. B. NNP cord-015569-vy49r1zd 39 12 Physalus Physalus NNP cord-015569-vy49r1zd 39 13 , , , cord-015569-vy49r1zd 39 14 we -PRON- PRP cord-015569-vy49r1zd 39 15 found find VBD cord-015569-vy49r1zd 39 16 point point NN cord-015569-vy49r1zd 39 17 mutiations mutiation NNS cord-015569-vy49r1zd 39 18 at at IN cord-015569-vy49r1zd 39 19 start start NN cord-015569-vy49r1zd 40 1 codon codon NNP cord-015569-vy49r1zd 40 2 ATG ATG NNP cord-015569-vy49r1zd 40 3 which which WDT cord-015569-vy49r1zd 40 4 is be VBZ cord-015569-vy49r1zd 40 5 A a DT cord-015569-vy49r1zd 40 6 to to IN cord-015569-vy49r1zd 40 7 G g NN cord-015569-vy49r1zd 40 8 substitution substitution NN cord-015569-vy49r1zd 40 9 , , , cord-015569-vy49r1zd 40 10 resulting result VBG cord-015569-vy49r1zd 40 11 in in IN cord-015569-vy49r1zd 40 12 GTG GTG NNP cord-015569-vy49r1zd 40 13 . . . cord-015569-vy49r1zd 41 1 By by IN cord-015569-vy49r1zd 41 2 this this DT cord-015569-vy49r1zd 41 3 mutation mutation NN cord-015569-vy49r1zd 41 4 , , , cord-015569-vy49r1zd 41 5 t1r1 t1r1 PRP cord-015569-vy49r1zd 41 6 could could MD cord-015569-vy49r1zd 41 7 not not RB cord-015569-vy49r1zd 41 8 be be VB cord-015569-vy49r1zd 41 9 translated translate VBN cord-015569-vy49r1zd 41 10 . . . cord-015569-vy49r1zd 42 1 Cell cell NN cord-015569-vy49r1zd 42 2 - - HYPH cord-015569-vy49r1zd 42 3 based base VBN cord-015569-vy49r1zd 42 4 expression expression NN cord-015569-vy49r1zd 42 5 studies study NNS cord-015569-vy49r1zd 42 6 have have VBP cord-015569-vy49r1zd 42 7 shown show VBN cord-015569-vy49r1zd 42 8 that that IN cord-015569-vy49r1zd 42 9 mammalian mammalian JJ cord-015569-vy49r1zd 42 10 T1R1 T1R1 NNP cord-015569-vy49r1zd 42 11 and and CC cord-015569-vy49r1zd 42 12 T1R3 T1R3 NNP cord-015569-vy49r1zd 42 13 G G NNP cord-015569-vy49r1zd 42 14 - - HYPH cord-015569-vy49r1zd 42 15 protein protein NN cord-015569-vy49r1zd 42 16 coupled coupled JJ cord-015569-vy49r1zd 42 17 receptors receptor NNS cord-015569-vy49r1zd 42 18 combine combine VBP cord-015569-vy49r1zd 42 19 to to TO cord-015569-vy49r1zd 42 20 form form VB cord-015569-vy49r1zd 42 21 a a DT cord-015569-vy49r1zd 42 22 broadly broadly RB cord-015569-vy49r1zd 42 23 tuned tune VBN cord-015569-vy49r1zd 42 24 L l NN cord-015569-vy49r1zd 42 25 - - HYPH cord-015569-vy49r1zd 42 26 amino amino NN cord-015569-vy49r1zd 42 27 - - HYPH cord-015569-vy49r1zd 42 28 acid acid NN cord-015569-vy49r1zd 42 29 receptor receptor NN cord-015569-vy49r1zd 42 30 . . . cord-015569-vy49r1zd 43 1 However however RB cord-015569-vy49r1zd 43 2 , , , cord-015569-vy49r1zd 43 3 contradictory contradictory JJ cord-015569-vy49r1zd 43 4 data datum NNS cord-015569-vy49r1zd 43 5 in in IN cord-015569-vy49r1zd 43 6 T1R3 T1R3 NNP cord-015569-vy49r1zd 43 7 knockout knockout NN cord-015569-vy49r1zd 43 8 ( ( -LRB- cord-015569-vy49r1zd 43 9 KO KO NNP cord-015569-vy49r1zd 43 10 ) ) -RRB- cord-015569-vy49r1zd 43 11 mouse mouse NN cord-015569-vy49r1zd 43 12 models model NNS cord-015569-vy49r1zd 43 13 have have VBP cord-015569-vy49r1zd 43 14 been be VBN cord-015569-vy49r1zd 43 15 reported report VBN cord-015569-vy49r1zd 43 16 on on IN cord-015569-vy49r1zd 43 17 taste taste NN cord-015569-vy49r1zd 43 18 nerve nerve NN cord-015569-vy49r1zd 43 19 responsiveness responsiveness NN cord-015569-vy49r1zd 43 20 . . . cord-015569-vy49r1zd 44 1 One one CD cord-015569-vy49r1zd 44 2 study study NN cord-015569-vy49r1zd 44 3 showed show VBD cord-015569-vy49r1zd 44 4 that that IN cord-015569-vy49r1zd 44 5 taste taste VBP cord-015569-vy49r1zd 44 6 nerve nerve NN cord-015569-vy49r1zd 44 7 responses response NNS cord-015569-vy49r1zd 44 8 to to IN cord-015569-vy49r1zd 44 9 amino amino NN cord-015569-vy49r1zd 44 10 acid acid NN cord-015569-vy49r1zd 44 11 stimuli stimulus NNS cord-015569-vy49r1zd 44 12 in in IN cord-015569-vy49r1zd 44 13 T1R3-KO t1r3-ko $ cord-015569-vy49r1zd 44 14 mice mouse NNS cord-015569-vy49r1zd 44 15 were be VBD cord-015569-vy49r1zd 44 16 totally totally RB cord-015569-vy49r1zd 44 17 abolished abolish VBN cord-015569-vy49r1zd 44 18 . . . cord-015569-vy49r1zd 45 1 The the DT cord-015569-vy49r1zd 45 2 other other JJ cord-015569-vy49r1zd 45 3 reported report VBD cord-015569-vy49r1zd 45 4 reduced reduce VBN cord-015569-vy49r1zd 45 5 but but CC cord-015569-vy49r1zd 45 6 not not RB cord-015569-vy49r1zd 45 7 abolished abolish VBN cord-015569-vy49r1zd 45 8 responses response NNS cord-015569-vy49r1zd 45 9 to to IN cord-015569-vy49r1zd 45 10 glutamate glutamate NN cord-015569-vy49r1zd 45 11 in in IN cord-015569-vy49r1zd 45 12 T1R3-KO t1r3-ko $ cord-015569-vy49r1zd 45 13 mice mouse NNS cord-015569-vy49r1zd 45 14 . . . cord-015569-vy49r1zd 46 1 In in IN cord-015569-vy49r1zd 46 2 the the DT cord-015569-vy49r1zd 46 3 present present JJ cord-015569-vy49r1zd 46 4 study study NN cord-015569-vy49r1zd 46 5 , , , cord-015569-vy49r1zd 46 6 we -PRON- PRP cord-015569-vy49r1zd 46 7 have have VBP cord-015569-vy49r1zd 46 8 tried try VBN cord-015569-vy49r1zd 46 9 to to TO cord-015569-vy49r1zd 46 10 recharacterize recharacterize VB cord-015569-vy49r1zd 46 11 the the DT cord-015569-vy49r1zd 46 12 role role NN cord-015569-vy49r1zd 46 13 of of IN cord-015569-vy49r1zd 46 14 T1R3 T1R3 NNP cord-015569-vy49r1zd 46 15 for for IN cord-015569-vy49r1zd 46 16 the the DT cord-015569-vy49r1zd 46 17 taste taste NN cord-015569-vy49r1zd 46 18 nerve nerve NN cord-015569-vy49r1zd 46 19 responses response NNS cord-015569-vy49r1zd 46 20 to to IN cord-015569-vy49r1zd 46 21 amino amino JJ cord-015569-vy49r1zd 46 22 acids acid NNS cord-015569-vy49r1zd 46 23 using use VBG cord-015569-vy49r1zd 46 24 a a DT cord-015569-vy49r1zd 46 25 wide wide JJ cord-015569-vy49r1zd 46 26 variety variety NN cord-015569-vy49r1zd 46 27 of of IN cord-015569-vy49r1zd 46 28 taste taste NN cord-015569-vy49r1zd 46 29 stimuli stimulus NNS cord-015569-vy49r1zd 46 30 . . . cord-015569-vy49r1zd 47 1 We -PRON- PRP cord-015569-vy49r1zd 47 2 have have VBP cord-015569-vy49r1zd 47 3 recorded record VBN cord-015569-vy49r1zd 47 4 from from IN cord-015569-vy49r1zd 47 5 whole whole JJ cord-015569-vy49r1zd 47 6 - - HYPH cord-015569-vy49r1zd 47 7 nerve nerve NN cord-015569-vy49r1zd 47 8 chorda chorda NN cord-015569-vy49r1zd 47 9 tympani tympani NN cord-015569-vy49r1zd 47 10 nerve nerve NN cord-015569-vy49r1zd 47 11 responses response NNS cord-015569-vy49r1zd 47 12 from from IN cord-015569-vy49r1zd 47 13 T1R3-KO t1r3-ko $ cord-015569-vy49r1zd 47 14 mice mouse NNS cord-015569-vy49r1zd 47 15 to to IN cord-015569-vy49r1zd 47 16 lingual lingual JJ cord-015569-vy49r1zd 47 17 application application NN cord-015569-vy49r1zd 47 18 of of IN cord-015569-vy49r1zd 47 19 various various JJ cord-015569-vy49r1zd 47 20 amino amino NN cord-015569-vy49r1zd 47 21 acid acid NN cord-015569-vy49r1zd 47 22 stimuli stimulus NNS cord-015569-vy49r1zd 47 23 including include VBG cord-015569-vy49r1zd 47 24 sweet sweet JJ cord-015569-vy49r1zd 47 25 - - HYPH cord-015569-vy49r1zd 47 26 and and CC cord-015569-vy49r1zd 47 27 umami umami NN cord-015569-vy49r1zd 47 28 - - HYPH cord-015569-vy49r1zd 47 29 tasting taste VBG cord-015569-vy49r1zd 47 30 amino amino NN cord-015569-vy49r1zd 47 31 acids acid NNS cord-015569-vy49r1zd 47 32 . . . cord-015569-vy49r1zd 48 1 Whole whole JJ cord-015569-vy49r1zd 48 2 - - HYPH cord-015569-vy49r1zd 48 3 nerve nerve NN cord-015569-vy49r1zd 48 4 recordings recording NNS cord-015569-vy49r1zd 48 5 of of IN cord-015569-vy49r1zd 48 6 chorda chorda NN cord-015569-vy49r1zd 48 7 tympani tympani NN cord-015569-vy49r1zd 48 8 nerve nerve NN cord-015569-vy49r1zd 48 9 in in IN cord-015569-vy49r1zd 48 10 T1R3-KO t1r3-ko $ cord-015569-vy49r1zd 48 11 mice mouse NNS cord-015569-vy49r1zd 48 12 showed show VBD cord-015569-vy49r1zd 48 13 robust robust JJ cord-015569-vy49r1zd 48 14 responses response NNS cord-015569-vy49r1zd 48 15 to to IN cord-015569-vy49r1zd 48 16 all all PDT cord-015569-vy49r1zd 48 17 the the DT cord-015569-vy49r1zd 48 18 tested test VBN cord-015569-vy49r1zd 48 19 amino amino NN cord-015569-vy49r1zd 48 20 acids acid NNS cord-015569-vy49r1zd 48 21 . . . cord-015569-vy49r1zd 49 1 Comparing compare VBG cord-015569-vy49r1zd 49 2 to to IN cord-015569-vy49r1zd 49 3 those those DT cord-015569-vy49r1zd 49 4 from from IN cord-015569-vy49r1zd 49 5 C57BL/6 C57BL/6 NNP cord-015569-vy49r1zd 49 6 wild wild JJ cord-015569-vy49r1zd 49 7 - - HYPH cord-015569-vy49r1zd 49 8 type type NN cord-015569-vy49r1zd 49 9 mice mice NN cord-015569-vy49r1zd 49 10 , , , cord-015569-vy49r1zd 49 11 only only RB cord-015569-vy49r1zd 49 12 small small JJ cord-015569-vy49r1zd 49 13 reductions reduction NNS cord-015569-vy49r1zd 49 14 of of IN cord-015569-vy49r1zd 49 15 responses response NNS cord-015569-vy49r1zd 49 16 to to IN cord-015569-vy49r1zd 49 17 glycine glycine NN cord-015569-vy49r1zd 49 18 and and CC cord-015569-vy49r1zd 49 19 L l NN cord-015569-vy49r1zd 49 20 - - HYPH cord-015569-vy49r1zd 49 21 alanine alanine NN cord-015569-vy49r1zd 49 22 , , , cord-015569-vy49r1zd 49 23 but but CC cord-015569-vy49r1zd 49 24 no no DT cord-015569-vy49r1zd 49 25 reduction reduction NN cord-015569-vy49r1zd 49 26 in in IN cord-015569-vy49r1zd 49 27 responses response NNS cord-015569-vy49r1zd 49 28 to to IN cord-015569-vy49r1zd 49 29 L l NN cord-015569-vy49r1zd 49 30 - - HYPH cord-015569-vy49r1zd 49 31 proline proline NN cord-015569-vy49r1zd 49 32 , , , cord-015569-vy49r1zd 49 33 L l NN cord-015569-vy49r1zd 49 34 - - HYPH cord-015569-vy49r1zd 49 35 serine serine NN cord-015569-vy49r1zd 49 36 , , , cord-015569-vy49r1zd 49 37 L l NN cord-015569-vy49r1zd 49 38 - - HYPH cord-015569-vy49r1zd 49 39 glutamine glutamine NNP cord-015569-vy49r1zd 49 40 and and CC cord-015569-vy49r1zd 49 41 L l NN cord-015569-vy49r1zd 49 42 - - HYPH cord-015569-vy49r1zd 49 43 glutamate glutamate NN cord-015569-vy49r1zd 49 44 salts salt NNS cord-015569-vy49r1zd 49 45 have have VBP cord-015569-vy49r1zd 49 46 been be VBN cord-015569-vy49r1zd 49 47 observed observe VBN cord-015569-vy49r1zd 49 48 . . . cord-015569-vy49r1zd 50 1 These these DT cord-015569-vy49r1zd 50 2 results result NNS cord-015569-vy49r1zd 50 3 suggest suggest VBP cord-015569-vy49r1zd 50 4 that that IN cord-015569-vy49r1zd 50 5 T1R3 T1R3 NNP cord-015569-vy49r1zd 50 6 mediated mediate VBN cord-015569-vy49r1zd 50 7 receptor receptor NN cord-015569-vy49r1zd 50 8 system system NN cord-015569-vy49r1zd 50 9 may may MD cord-015569-vy49r1zd 50 10 play play VB cord-015569-vy49r1zd 50 11 limited limited JJ cord-015569-vy49r1zd 50 12 role role NN cord-015569-vy49r1zd 50 13 for for IN cord-015569-vy49r1zd 50 14 detection detection NN cord-015569-vy49r1zd 50 15 of of IN cord-015569-vy49r1zd 50 16 amino amino JJ cord-015569-vy49r1zd 50 17 acids acid NNS cord-015569-vy49r1zd 50 18 . . . cord-015569-vy49r1zd 51 1 Type type NN cord-015569-vy49r1zd 51 2 III III NNP cord-015569-vy49r1zd 51 3 taste taste NN cord-015569-vy49r1zd 51 4 cells cell NNS cord-015569-vy49r1zd 51 5 play play VBP cord-015569-vy49r1zd 51 6 to to TO cord-015569-vy49r1zd 51 7 act act VB cord-015569-vy49r1zd 51 8 to to TO cord-015569-vy49r1zd 51 9 receive receive VB cord-015569-vy49r1zd 51 10 sour sour JJ cord-015569-vy49r1zd 51 11 taste taste NN cord-015569-vy49r1zd 51 12 and and CC cord-015569-vy49r1zd 51 13 also also RB cord-015569-vy49r1zd 51 14 to to TO cord-015569-vy49r1zd 51 15 act act VB cord-015569-vy49r1zd 51 16 as as IN cord-015569-vy49r1zd 51 17 ' ' '' cord-015569-vy49r1zd 51 18 ' ' `` cord-015569-vy49r1zd 51 19 taste taste NN cord-015569-vy49r1zd 51 20 integration integration NN cord-015569-vy49r1zd 51 21 cell cell NN cord-015569-vy49r1zd 51 22 ' ' '' cord-015569-vy49r1zd 51 23 ' ' '' cord-015569-vy49r1zd 51 24 to to TO cord-015569-vy49r1zd 51 25 transmit transmit VB cord-015569-vy49r1zd 51 26 taste taste NN cord-015569-vy49r1zd 51 27 information information NN cord-015569-vy49r1zd 51 28 from from IN cord-015569-vy49r1zd 51 29 type type NN cord-015569-vy49r1zd 51 30 II II NNP cord-015569-vy49r1zd 51 31 taste taste NN cord-015569-vy49r1zd 51 32 cells cell NNS cord-015569-vy49r1zd 51 33 through through IN cord-015569-vy49r1zd 51 34 ATP ATP NNP cord-015569-vy49r1zd 51 35 . . . cord-015569-vy49r1zd 52 1 But but CC cord-015569-vy49r1zd 52 2 , , , cord-015569-vy49r1zd 52 3 it -PRON- PRP cord-015569-vy49r1zd 52 4 is be VBZ cord-015569-vy49r1zd 52 5 not not RB cord-015569-vy49r1zd 52 6 known know VBN cord-015569-vy49r1zd 52 7 whether whether IN cord-015569-vy49r1zd 52 8 a a DT cord-015569-vy49r1zd 52 9 type type NN cord-015569-vy49r1zd 52 10 III iii CD cord-015569-vy49r1zd 52 11 taste taste NN cord-015569-vy49r1zd 52 12 cell cell NN cord-015569-vy49r1zd 52 13 has have VBZ cord-015569-vy49r1zd 52 14 both both DT cord-015569-vy49r1zd 52 15 roles role NNS cord-015569-vy49r1zd 52 16 and and CC cord-015569-vy49r1zd 52 17 whether whether IN cord-015569-vy49r1zd 52 18 two two CD cord-015569-vy49r1zd 52 19 kinds kind NNS cord-015569-vy49r1zd 52 20 of of IN cord-015569-vy49r1zd 52 21 type type NN cord-015569-vy49r1zd 52 22 III iii CD cord-015569-vy49r1zd 52 23 taste taste NN cord-015569-vy49r1zd 52 24 cells cell NNS cord-015569-vy49r1zd 52 25 share share VBP cord-015569-vy49r1zd 52 26 each each DT cord-015569-vy49r1zd 52 27 role role NN cord-015569-vy49r1zd 52 28 separately separately RB cord-015569-vy49r1zd 52 29 . . . cord-015569-vy49r1zd 53 1 Using use VBG cord-015569-vy49r1zd 53 2 calcium calcium NN cord-015569-vy49r1zd 53 3 imaging imaging NN cord-015569-vy49r1zd 53 4 and and CC cord-015569-vy49r1zd 53 5 immunocytochemistry immunocytochemistry NN cord-015569-vy49r1zd 53 6 , , , cord-015569-vy49r1zd 53 7 we -PRON- PRP cord-015569-vy49r1zd 53 8 revealed reveal VBD cord-015569-vy49r1zd 53 9 that that IN cord-015569-vy49r1zd 53 10 ATP ATP NNP cord-015569-vy49r1zd 53 11 activates activate VBZ cord-015569-vy49r1zd 53 12 type type NN cord-015569-vy49r1zd 53 13 II II NNP cord-015569-vy49r1zd 53 14 and and CC cord-015569-vy49r1zd 53 15 III III NNP cord-015569-vy49r1zd 53 16 taste taste NN cord-015569-vy49r1zd 53 17 cells cell NNS cord-015569-vy49r1zd 53 18 and and CC cord-015569-vy49r1zd 53 19 HCl hcl NN cord-015569-vy49r1zd 53 20 activates activate VBZ cord-015569-vy49r1zd 53 21 type type NN cord-015569-vy49r1zd 53 22 III iii CD cord-015569-vy49r1zd 53 23 taste taste NN cord-015569-vy49r1zd 53 24 cells cell NNS cord-015569-vy49r1zd 53 25 , , , cord-015569-vy49r1zd 53 26 and and CC cord-015569-vy49r1zd 53 27 also also RB cord-015569-vy49r1zd 53 28 that that IN cord-015569-vy49r1zd 53 29 HCl HCl NNP cord-015569-vy49r1zd 53 30 and and CC cord-015569-vy49r1zd 53 31 ATP ATP NNP cord-015569-vy49r1zd 53 32 activate activate VBP cord-015569-vy49r1zd 53 33 separate separate JJ cord-015569-vy49r1zd 53 34 subpopulations subpopulation NNS cord-015569-vy49r1zd 53 35 of of IN cord-015569-vy49r1zd 53 36 taste taste NN cord-015569-vy49r1zd 53 37 cells cell NNS cord-015569-vy49r1zd 53 38 . . . cord-015569-vy49r1zd 54 1 We -PRON- PRP cord-015569-vy49r1zd 54 2 also also RB cord-015569-vy49r1zd 54 3 showed show VBD cord-015569-vy49r1zd 54 4 that that IN cord-015569-vy49r1zd 54 5 sour sour RB cord-015569-vy49r1zd 54 6 - - HYPH cord-015569-vy49r1zd 54 7 responding respond VBG cord-015569-vy49r1zd 54 8 taste taste NN cord-015569-vy49r1zd 54 9 cells cell NNS cord-015569-vy49r1zd 54 10 do do VBP cord-015569-vy49r1zd 54 11 not not RB cord-015569-vy49r1zd 54 12 have have VB cord-015569-vy49r1zd 54 13 P2X p2x CD cord-015569-vy49r1zd 54 14 2 2 CD cord-015569-vy49r1zd 54 15 and and CC cord-015569-vy49r1zd 54 16 P2Y p2y NN cord-015569-vy49r1zd 54 17 1 1 CD cord-015569-vy49r1zd 54 18 as as IN cord-015569-vy49r1zd 54 19 ATP ATP NNP cord-015569-vy49r1zd 54 20 receptors receptor NNS cord-015569-vy49r1zd 54 21 in in IN cord-015569-vy49r1zd 54 22 taste taste NN cord-015569-vy49r1zd 54 23 buds bud NNS cord-015569-vy49r1zd 54 24 . . . cord-015569-vy49r1zd 55 1 Moreover moreover RB cord-015569-vy49r1zd 55 2 , , , cord-015569-vy49r1zd 55 3 we -PRON- PRP cord-015569-vy49r1zd 55 4 carried carry VBD cord-015569-vy49r1zd 55 5 out out RP cord-015569-vy49r1zd 55 6 double double JJ cord-015569-vy49r1zd 55 7 cell cell NN cord-015569-vy49r1zd 55 8 staining staining NN cord-015569-vy49r1zd 55 9 of of IN cord-015569-vy49r1zd 55 10 mice mice NN cord-015569-vy49r1zd 55 11 circumvallate circumvallate JJ cord-015569-vy49r1zd 55 12 papillae papilla NNS cord-015569-vy49r1zd 55 13 using use VBG cord-015569-vy49r1zd 55 14 antibodies antibody NNS cord-015569-vy49r1zd 55 15 to to IN cord-015569-vy49r1zd 55 16 ATP ATP NNP cord-015569-vy49r1zd 55 17 receptor receptor NN cord-015569-vy49r1zd 55 18 ( ( -LRB- cord-015569-vy49r1zd 55 19 P2X P2X NNP cord-015569-vy49r1zd 55 20 2 2 CD cord-015569-vy49r1zd 55 21 , , , cord-015569-vy49r1zd 55 22 P2X p2x NN cord-015569-vy49r1zd 55 23 3 3 CD cord-015569-vy49r1zd 55 24 and and CC cord-015569-vy49r1zd 55 25 P2Y p2y NN cord-015569-vy49r1zd 55 26 1 1 CD cord-015569-vy49r1zd 55 27 ) ) -RRB- cord-015569-vy49r1zd 55 28 and and CC cord-015569-vy49r1zd 55 29 sour sour JJ cord-015569-vy49r1zd 55 30 taste taste NN cord-015569-vy49r1zd 55 31 receptor receptor NN cord-015569-vy49r1zd 55 32 ( ( -LRB- cord-015569-vy49r1zd 55 33 PKD2L1 pkd2l1 NN cord-015569-vy49r1zd 55 34 ) ) -RRB- cord-015569-vy49r1zd 55 35 using use VBG cord-015569-vy49r1zd 55 36 an an DT cord-015569-vy49r1zd 55 37 antibody antibody NN cord-015569-vy49r1zd 55 38 to to TO cord-015569-vy49r1zd 55 39 type type VB cord-015569-vy49r1zd 55 40 II II NNP cord-015569-vy49r1zd 55 41 taste taste NN cord-015569-vy49r1zd 55 42 cell cell NN cord-015569-vy49r1zd 55 43 marker marker NN cord-015569-vy49r1zd 55 44 ( ( -LRB- cord-015569-vy49r1zd 55 45 PLCb2 plcb2 NN cord-015569-vy49r1zd 55 46 ) ) -RRB- cord-015569-vy49r1zd 55 47 and and CC cord-015569-vy49r1zd 55 48 type type NN cord-015569-vy49r1zd 55 49 III iii CD cord-015569-vy49r1zd 55 50 taste taste NN cord-015569-vy49r1zd 55 51 cell cell NN cord-015569-vy49r1zd 55 52 marker marker NN cord-015569-vy49r1zd 55 53 ( ( -LRB- cord-015569-vy49r1zd 55 54 PGP9.5 PGP9.5 NNP cord-015569-vy49r1zd 55 55 ) ) -RRB- cord-015569-vy49r1zd 55 56 . . . cord-015569-vy49r1zd 56 1 It -PRON- PRP cord-015569-vy49r1zd 56 2 was be VBD cord-015569-vy49r1zd 56 3 shown show VBN cord-015569-vy49r1zd 56 4 that that IN cord-015569-vy49r1zd 56 5 P2X p2x NN cord-015569-vy49r1zd 56 6 2 2 CD cord-015569-vy49r1zd 56 7 and and CC cord-015569-vy49r1zd 56 8 P2X p2x NN cord-015569-vy49r1zd 56 9 3 3 CD cord-015569-vy49r1zd 56 10 are be VBP cord-015569-vy49r1zd 56 11 expressed express VBN cord-015569-vy49r1zd 56 12 in in IN cord-015569-vy49r1zd 56 13 taste taste NN cord-015569-vy49r1zd 56 14 nerves nerve NNS cord-015569-vy49r1zd 56 15 , , , cord-015569-vy49r1zd 56 16 P2Y p2y NN cord-015569-vy49r1zd 56 17 1 1 CD cord-015569-vy49r1zd 56 18 is be VBZ cord-015569-vy49r1zd 56 19 in in IN cord-015569-vy49r1zd 56 20 type type NN cord-015569-vy49r1zd 56 21 II ii CD cord-015569-vy49r1zd 56 22 taste taste NN cord-015569-vy49r1zd 56 23 cells cell NNS cord-015569-vy49r1zd 56 24 , , , cord-015569-vy49r1zd 56 25 and and CC cord-015569-vy49r1zd 56 26 PKD2L1 PKD2L1 NNP cord-015569-vy49r1zd 56 27 is be VBZ cord-015569-vy49r1zd 56 28 in in IN cord-015569-vy49r1zd 56 29 type type NN cord-015569-vy49r1zd 56 30 III iii CD cord-015569-vy49r1zd 56 31 taste taste NN cord-015569-vy49r1zd 56 32 cells cell NNS cord-015569-vy49r1zd 56 33 . . . cord-015569-vy49r1zd 57 1 No no DT cord-015569-vy49r1zd 57 2 taste taste NN cord-015569-vy49r1zd 57 3 cell cell NN cord-015569-vy49r1zd 57 4 was be VBD cord-015569-vy49r1zd 57 5 stained stain VBN cord-015569-vy49r1zd 57 6 by by IN cord-015569-vy49r1zd 57 7 both both DT cord-015569-vy49r1zd 57 8 ATP ATP NNP cord-015569-vy49r1zd 57 9 receptor receptor NN cord-015569-vy49r1zd 57 10 and and CC cord-015569-vy49r1zd 57 11 sour sour JJ cord-015569-vy49r1zd 57 12 taste taste NN cord-015569-vy49r1zd 57 13 receptor receptor NN cord-015569-vy49r1zd 57 14 . . . cord-015569-vy49r1zd 58 1 Although although IN cord-015569-vy49r1zd 58 2 we -PRON- PRP cord-015569-vy49r1zd 58 3 could could MD cord-015569-vy49r1zd 58 4 not not RB cord-015569-vy49r1zd 58 5 cover cover VB cord-015569-vy49r1zd 58 6 all all PDT cord-015569-vy49r1zd 58 7 the the DT cord-015569-vy49r1zd 58 8 ATP ATP NNP cord-015569-vy49r1zd 58 9 or or CC cord-015569-vy49r1zd 58 10 sour sour JJ cord-015569-vy49r1zd 58 11 taste taste NN cord-015569-vy49r1zd 58 12 receptors receptor NNS cord-015569-vy49r1zd 58 13 , , , cord-015569-vy49r1zd 58 14 these these DT cord-015569-vy49r1zd 58 15 results result NNS cord-015569-vy49r1zd 58 16 suggest suggest VBP cord-015569-vy49r1zd 58 17 that that IN cord-015569-vy49r1zd 58 18 there there EX cord-015569-vy49r1zd 58 19 are be VBP cord-015569-vy49r1zd 58 20 the the DT cord-015569-vy49r1zd 58 21 two two CD cord-015569-vy49r1zd 58 22 separate separate JJ cord-015569-vy49r1zd 58 23 subpopulations subpopulation NNS cord-015569-vy49r1zd 58 24 of of IN cord-015569-vy49r1zd 58 25 type type NN cord-015569-vy49r1zd 58 26 III iii CD cord-015569-vy49r1zd 58 27 taste taste NN cord-015569-vy49r1zd 58 28 cells cell NNS cord-015569-vy49r1zd 58 29 : : : cord-015569-vy49r1zd 58 30 the the DT cord-015569-vy49r1zd 58 31 one one NN cord-015569-vy49r1zd 58 32 sensing sense VBG cord-015569-vy49r1zd 58 33 sour sour JJ cord-015569-vy49r1zd 58 34 taste taste NN cord-015569-vy49r1zd 58 35 and and CC cord-015569-vy49r1zd 58 36 the the DT cord-015569-vy49r1zd 58 37 other other JJ cord-015569-vy49r1zd 58 38 accepting accept VBG cord-015569-vy49r1zd 58 39 the the DT cord-015569-vy49r1zd 58 40 ATP ATP NNP cord-015569-vy49r1zd 58 41 released release VBN cord-015569-vy49r1zd 58 42 from from IN cord-015569-vy49r1zd 58 43 type type NN cord-015569-vy49r1zd 58 44 II II NNP cord-015569-vy49r1zd 58 45 taste taste NN cord-015569-vy49r1zd 58 46 cells cell NNS cord-015569-vy49r1zd 58 47 . . . cord-015569-vy49r1zd 59 1 # # $ cord-015569-vy49r1zd 59 2 6 6 CD cord-015569-vy49r1zd 59 3 Development development NN cord-015569-vy49r1zd 59 4 of of IN cord-015569-vy49r1zd 59 5 gustatory gustatory JJ cord-015569-vy49r1zd 59 6 papillae papilla NNS cord-015569-vy49r1zd 59 7 in in IN cord-015569-vy49r1zd 59 8 the the DT cord-015569-vy49r1zd 59 9 absence absence NN cord-015569-vy49r1zd 59 10 of of IN cord-015569-vy49r1zd 60 1 Six1 six1 JJ cord-015569-vy49r1zd 60 2 and and CC cord-015569-vy49r1zd 60 3 Six4 Six4 NNP cord-015569-vy49r1zd 60 4 Six Six NNP cord-015569-vy49r1zd 60 5 family family NN cord-015569-vy49r1zd 60 6 genes gene NNS cord-015569-vy49r1zd 60 7 encode encode VBP cord-015569-vy49r1zd 60 8 homeobox homeobox NN cord-015569-vy49r1zd 60 9 transcription transcription NN cord-015569-vy49r1zd 60 10 factors factor NNS cord-015569-vy49r1zd 60 11 , , , cord-015569-vy49r1zd 60 12 and and CC cord-015569-vy49r1zd 60 13 a a DT cord-015569-vy49r1zd 60 14 deficiency deficiency NN cord-015569-vy49r1zd 60 15 in in IN cord-015569-vy49r1zd 60 16 them -PRON- PRP cord-015569-vy49r1zd 60 17 leads lead VBZ cord-015569-vy49r1zd 60 18 to to IN cord-015569-vy49r1zd 60 19 abnormal abnormal JJ cord-015569-vy49r1zd 60 20 structures structure NNS cord-015569-vy49r1zd 60 21 of of IN cord-015569-vy49r1zd 60 22 the the DT cord-015569-vy49r1zd 60 23 sensory sensory JJ cord-015569-vy49r1zd 60 24 organs organ NNS cord-015569-vy49r1zd 60 25 . . . cord-015569-vy49r1zd 61 1 In in IN cord-015569-vy49r1zd 61 2 a a DT cord-015569-vy49r1zd 61 3 previous previous JJ cord-015569-vy49r1zd 61 4 paper paper NN cord-015569-vy49r1zd 61 5 , , , cord-015569-vy49r1zd 61 6 Six1 Six1 NNP cord-015569-vy49r1zd 61 7 was be VBD cord-015569-vy49r1zd 61 8 reported report VBN cord-015569-vy49r1zd 61 9 to to TO cord-015569-vy49r1zd 61 10 be be VB cord-015569-vy49r1zd 61 11 expressed express VBN cord-015569-vy49r1zd 61 12 in in IN cord-015569-vy49r1zd 61 13 the the DT cord-015569-vy49r1zd 61 14 taste taste NN cord-015569-vy49r1zd 61 15 bud bud NN cord-015569-vy49r1zd 61 16 - - HYPH cord-015569-vy49r1zd 61 17 bearing bear VBG cord-015569-vy49r1zd 61 18 lingual lingual JJ cord-015569-vy49r1zd 61 19 papillae papilla NNS cord-015569-vy49r1zd 61 20 of of IN cord-015569-vy49r1zd 61 21 mice mouse NNS cord-015569-vy49r1zd 61 22 , , , cord-015569-vy49r1zd 61 23 and and CC cord-015569-vy49r1zd 61 24 loss loss NN cord-015569-vy49r1zd 61 25 of of IN cord-015569-vy49r1zd 61 26 Six1 Six1 NNP cord-015569-vy49r1zd 61 27 affected affect VBD cord-015569-vy49r1zd 61 28 the the DT cord-015569-vy49r1zd 61 29 development development NN cord-015569-vy49r1zd 61 30 of of IN cord-015569-vy49r1zd 61 31 these these DT cord-015569-vy49r1zd 61 32 gustatory gustatory JJ cord-015569-vy49r1zd 61 33 papillae papilla NNS cord-015569-vy49r1zd 61 34 . . . cord-015569-vy49r1zd 62 1 We -PRON- PRP cord-015569-vy49r1zd 62 2 show show VBP cord-015569-vy49r1zd 62 3 here here RB cord-015569-vy49r1zd 62 4 that that IN cord-015569-vy49r1zd 62 5 embryos embryo NNS cord-015569-vy49r1zd 62 6 lacking lack VBG cord-015569-vy49r1zd 62 7 both both CC cord-015569-vy49r1zd 62 8 Six1 Six1 NNP cord-015569-vy49r1zd 62 9 and and CC cord-015569-vy49r1zd 62 10 Six4 Six4 NNP cord-015569-vy49r1zd 62 11 revealed reveal VBD cord-015569-vy49r1zd 62 12 more more RBR cord-015569-vy49r1zd 62 13 severe severe JJ cord-015569-vy49r1zd 62 14 abnormalities abnormality NNS cord-015569-vy49r1zd 62 15 than than IN cord-015569-vy49r1zd 62 16 those those DT cord-015569-vy49r1zd 62 17 lacking lack VBG cord-015569-vy49r1zd 62 18 Six1 Six1 NNP cord-015569-vy49r1zd 62 19 alone alone RB cord-015569-vy49r1zd 62 20 during during IN cord-015569-vy49r1zd 62 21 morphogenesis morphogenesis NN cord-015569-vy49r1zd 62 22 of of IN cord-015569-vy49r1zd 62 23 their -PRON- PRP$ cord-015569-vy49r1zd 62 24 gustatory gustatory JJ cord-015569-vy49r1zd 62 25 papillae papilla NNS cord-015569-vy49r1zd 62 26 . . . cord-015569-vy49r1zd 63 1 By by IN cord-015569-vy49r1zd 63 2 in in IN cord-015569-vy49r1zd 63 3 situ situ NN cord-015569-vy49r1zd 63 4 hybridization hybridization NN cord-015569-vy49r1zd 63 5 , , , cord-015569-vy49r1zd 63 6 Six4 Six4 NNP cord-015569-vy49r1zd 63 7 was be VBD cord-015569-vy49r1zd 63 8 shown show VBN cord-015569-vy49r1zd 63 9 to to TO cord-015569-vy49r1zd 63 10 be be VB cord-015569-vy49r1zd 63 11 broadly broadly RB cord-015569-vy49r1zd 63 12 distributed distribute VBN cord-015569-vy49r1zd 63 13 in in IN cord-015569-vy49r1zd 63 14 the the DT cord-015569-vy49r1zd 63 15 epithelium epithelium NN cord-015569-vy49r1zd 63 16 of of IN cord-015569-vy49r1zd 63 17 the the DT cord-015569-vy49r1zd 63 18 lateral lateral JJ cord-015569-vy49r1zd 63 19 lingual lingual JJ cord-015569-vy49r1zd 63 20 swellings swelling NNS cord-015569-vy49r1zd 63 21 at at IN cord-015569-vy49r1zd 63 22 embryonic embryonic JJ cord-015569-vy49r1zd 63 23 day day NN cord-015569-vy49r1zd 64 1 ( ( -LRB- cord-015569-vy49r1zd 64 2 E e NN cord-015569-vy49r1zd 64 3 ) ) -RRB- cord-015569-vy49r1zd 64 4 11.5 11.5 CD cord-015569-vy49r1zd 64 5 , , , cord-015569-vy49r1zd 64 6 and and CC cord-015569-vy49r1zd 64 7 in in IN cord-015569-vy49r1zd 64 8 the the DT cord-015569-vy49r1zd 64 9 tongue tongue NN cord-015569-vy49r1zd 64 10 epithelium epithelium NN cord-015569-vy49r1zd 64 11 , , , cord-015569-vy49r1zd 64 12 mesenchyme mesenchyme NNS cord-015569-vy49r1zd 64 13 , , , cord-015569-vy49r1zd 64 14 and and CC cord-015569-vy49r1zd 64 15 muscles muscle NNS cord-015569-vy49r1zd 64 16 at at IN cord-015569-vy49r1zd 64 17 E12.5 E12.5 NNP cord-015569-vy49r1zd 64 18 . . . cord-015569-vy49r1zd 65 1 From from IN cord-015569-vy49r1zd 65 2 E14 E14 NNP cord-015569-vy49r1zd 65 3 , , , cord-015569-vy49r1zd 65 4 Six4 Six4 NNP cord-015569-vy49r1zd 65 5 was be VBD cord-015569-vy49r1zd 65 6 similar similar JJ cord-015569-vy49r1zd 65 7 in in IN cord-015569-vy49r1zd 65 8 expression expression NN cord-015569-vy49r1zd 65 9 pattern pattern NN cord-015569-vy49r1zd 65 10 to to IN cord-015569-vy49r1zd 65 11 Six1 Six1 NNP cord-015569-vy49r1zd 65 12 , , , cord-015569-vy49r1zd 65 13 as as IN cord-015569-vy49r1zd 65 14 previously previously RB cord-015569-vy49r1zd 65 15 reported report VBN cord-015569-vy49r1zd 65 16 ; ; : cord-015569-vy49r1zd 65 17 and and CC cord-015569-vy49r1zd 65 18 in in IN cord-015569-vy49r1zd 65 19 the the DT cord-015569-vy49r1zd 65 20 fungiform fungiform JJ cord-015569-vy49r1zd 65 21 papillae papilla NNS cord-015569-vy49r1zd 65 22 , , , cord-015569-vy49r1zd 65 23 Six4 Six4 NNP cord-015569-vy49r1zd 65 24 was be VBD cord-015569-vy49r1zd 65 25 expressed express VBN cord-015569-vy49r1zd 65 26 in in IN cord-015569-vy49r1zd 65 27 the the DT cord-015569-vy49r1zd 65 28 epithelium epithelium NN cord-015569-vy49r1zd 65 29 at at IN cord-015569-vy49r1zd 65 30 E14-E16.5 E14-E16.5 NNP cord-015569-vy49r1zd 65 31 . . . cord-015569-vy49r1zd 66 1 In in IN cord-015569-vy49r1zd 66 2 the the DT cord-015569-vy49r1zd 66 3 circumvallate circumvallate JJ cord-015569-vy49r1zd 66 4 and and CC cord-015569-vy49r1zd 66 5 foliate foliate JJ cord-015569-vy49r1zd 66 6 papillae papilla NNS cord-015569-vy49r1zd 66 7 , , , cord-015569-vy49r1zd 66 8 Six4 six4 JJ cord-015569-vy49r1zd 66 9 expression expression NN cord-015569-vy49r1zd 66 10 observed observe VBD cord-015569-vy49r1zd 66 11 in in IN cord-015569-vy49r1zd 66 12 the the DT cord-015569-vy49r1zd 66 13 trench trench NN cord-015569-vy49r1zd 66 14 wall wall NN cord-015569-vy49r1zd 66 15 of of IN cord-015569-vy49r1zd 66 16 these these DT cord-015569-vy49r1zd 66 17 papillae papilla NNS cord-015569-vy49r1zd 66 18 at at IN cord-015569-vy49r1zd 66 19 E15.5-P0 E15.5-P0 NNP cord-015569-vy49r1zd 66 20 . . . cord-015569-vy49r1zd 67 1 Although although IN cord-015569-vy49r1zd 67 2 Six4-deficient six4-deficient JJ cord-015569-vy49r1zd 67 3 mice mouse NNS cord-015569-vy49r1zd 67 4 had have VBD cord-015569-vy49r1zd 67 5 no no DT cord-015569-vy49r1zd 67 6 abnormalities abnormality NNS cord-015569-vy49r1zd 67 7 , , . cord-015569-vy49r1zd 68 1 Six1 six1 JJ cord-015569-vy49r1zd 68 2 / / SYM cord-015569-vy49r1zd 68 3 Six4-deficient six4-deficient JJ cord-015569-vy49r1zd 68 4 mice mouse NNS cord-015569-vy49r1zd 68 5 showed show VBD cord-015569-vy49r1zd 68 6 distinct distinct JJ cord-015569-vy49r1zd 68 7 morphological morphological JJ cord-015569-vy49r1zd 68 8 changes change NNS cord-015569-vy49r1zd 68 9 : : : cord-015569-vy49r1zd 68 10 fusion fusion NN cord-015569-vy49r1zd 68 11 of of IN cord-015569-vy49r1zd 68 12 the the DT cord-015569-vy49r1zd 68 13 lateral lateral JJ cord-015569-vy49r1zd 68 14 lingual lingual JJ cord-015569-vy49r1zd 68 15 swellings swelling NNS cord-015569-vy49r1zd 68 16 was be VBD cord-015569-vy49r1zd 68 17 delayed delay VBN cord-015569-vy49r1zd 68 18 , , , cord-015569-vy49r1zd 68 19 and and CC cord-015569-vy49r1zd 68 20 the the DT cord-015569-vy49r1zd 68 21 tongue tongue NN cord-015569-vy49r1zd 68 22 was be VBD cord-015569-vy49r1zd 68 23 poorly poorly RB cord-015569-vy49r1zd 68 24 developed develop VBN cord-015569-vy49r1zd 68 25 . . . cord-015569-vy49r1zd 69 1 The the DT cord-015569-vy49r1zd 69 2 primordia primordium NNS cord-015569-vy49r1zd 69 3 of of IN cord-015569-vy49r1zd 69 4 fungiform fungiform NN cord-015569-vy49r1zd 69 5 papillae papilla NNS cord-015569-vy49r1zd 69 6 appeared appear VBD cord-015569-vy49r1zd 69 7 earlier early RBR cord-015569-vy49r1zd 69 8 than than IN cord-015569-vy49r1zd 69 9 those those DT cord-015569-vy49r1zd 69 10 in in IN cord-015569-vy49r1zd 69 11 the the DT cord-015569-vy49r1zd 69 12 wild wild JJ cord-015569-vy49r1zd 69 13 - - HYPH cord-015569-vy49r1zd 69 14 type type NN cord-015569-vy49r1zd 69 15 or or CC cord-015569-vy49r1zd 69 16 Six1-deficient six1-deficient NN cord-015569-vy49r1zd 69 17 mice mouse NNS cord-015569-vy49r1zd 69 18 , , , cord-015569-vy49r1zd 69 19 and and CC cord-015569-vy49r1zd 69 20 the the DT cord-015569-vy49r1zd 69 21 papillae papilla NNS cord-015569-vy49r1zd 69 22 rapidly rapidly RB cord-015569-vy49r1zd 69 23 increased increase VBD cord-015569-vy49r1zd 69 24 in in IN cord-015569-vy49r1zd 69 25 size size NN cord-015569-vy49r1zd 69 26 ; ; : cord-015569-vy49r1zd 69 27 thus thus RB cord-015569-vy49r1zd 69 28 fusion fusion NN cord-015569-vy49r1zd 69 29 of of IN cord-015569-vy49r1zd 69 30 each each DT cord-015569-vy49r1zd 69 31 papilla papilla NN cord-015569-vy49r1zd 69 32 was be VBD cord-015569-vy49r1zd 69 33 evident evident JJ cord-015569-vy49r1zd 69 34 . . . cord-015569-vy49r1zd 70 1 The the DT cord-015569-vy49r1zd 70 2 circumvallate circumvallate JJ cord-015569-vy49r1zd 70 3 papillae papilla NNS cord-015569-vy49r1zd 70 4 showed show VBD cord-015569-vy49r1zd 70 5 severe severe JJ cord-015569-vy49r1zd 70 6 defects defect NNS cord-015569-vy49r1zd 70 7 ; ; , cord-015569-vy49r1zd 70 8 e.g. e.g. RB cord-015569-vy49r1zd 70 9 , , , cord-015569-vy49r1zd 70 10 invagination invagination NN cord-015569-vy49r1zd 70 11 of of IN cord-015569-vy49r1zd 70 12 the the DT cord-015569-vy49r1zd 70 13 trenches trench NNS cord-015569-vy49r1zd 70 14 started start VBD cord-015569-vy49r1zd 70 15 asymmetrically asymmetrically RB cord-015569-vy49r1zd 70 16 , , , cord-015569-vy49r1zd 70 17 which which WDT cord-015569-vy49r1zd 70 18 resulted result VBD cord-015569-vy49r1zd 70 19 in in IN cord-015569-vy49r1zd 70 20 longer long JJR cord-015569-vy49r1zd 70 21 and and CC cord-015569-vy49r1zd 70 22 shorter short JJR cord-015569-vy49r1zd 70 23 trenches trench NNS cord-015569-vy49r1zd 70 24 . . . cord-015569-vy49r1zd 71 1 The the DT cord-015569-vy49r1zd 71 2 foliate foliate JJ cord-015569-vy49r1zd 71 3 papillae papilla NNS cord-015569-vy49r1zd 71 4 elevated elevate VBD cord-015569-vy49r1zd 71 5 initially initially RB cord-015569-vy49r1zd 71 6 , , , cord-015569-vy49r1zd 71 7 and and CC cord-015569-vy49r1zd 71 8 showed show VBD cord-015569-vy49r1zd 71 9 stunted stunted JJ cord-015569-vy49r1zd 71 10 trenches trench NNS cord-015569-vy49r1zd 71 11 . . . cord-015569-vy49r1zd 72 1 Therefore therefore RB cord-015569-vy49r1zd 72 2 , , , cord-015569-vy49r1zd 72 3 Six1 Six1 NNP cord-015569-vy49r1zd 72 4 and and CC cord-015569-vy49r1zd 72 5 Six4 Six4 NNP cord-015569-vy49r1zd 72 6 function function NN cord-015569-vy49r1zd 72 7 synergistically synergistically RB cord-015569-vy49r1zd 72 8 to to TO cord-015569-vy49r1zd 72 9 form form VB cord-015569-vy49r1zd 72 10 gustatory gustatory JJ cord-015569-vy49r1zd 72 11 papillae papilla NNS cord-015569-vy49r1zd 72 12 during during IN cord-015569-vy49r1zd 72 13 development development NN cord-015569-vy49r1zd 72 14 of of IN cord-015569-vy49r1zd 72 15 the the DT cord-015569-vy49r1zd 72 16 tongue tongue NN cord-015569-vy49r1zd 72 17 . . . cord-015569-vy49r1zd 73 1 The the DT cord-015569-vy49r1zd 73 2 life life NN cord-015569-vy49r1zd 73 3 span span NN cord-015569-vy49r1zd 73 4 of of IN cord-015569-vy49r1zd 73 5 taste taste NN cord-015569-vy49r1zd 73 6 cells cell NNS cord-015569-vy49r1zd 73 7 was be VBD cord-015569-vy49r1zd 73 8 previously previously RB cord-015569-vy49r1zd 73 9 estimated estimate VBN cord-015569-vy49r1zd 73 10 as as IN cord-015569-vy49r1zd 73 11 10 10 CD cord-015569-vy49r1zd 73 12 - - SYM cord-015569-vy49r1zd 73 13 14 14 CD cord-015569-vy49r1zd 73 14 days day NNS cord-015569-vy49r1zd 73 15 by by IN cord-015569-vy49r1zd 73 16 labeling label VBG cord-015569-vy49r1zd 73 17 newly newly RB cord-015569-vy49r1zd 73 18 proliferated proliferate VBN cord-015569-vy49r1zd 73 19 taste taste NN cord-015569-vy49r1zd 73 20 cells cell NNS cord-015569-vy49r1zd 73 21 with with IN cord-015569-vy49r1zd 73 22 radioactive radioactive JJ cord-015569-vy49r1zd 73 23 3 3 CD cord-015569-vy49r1zd 73 24 Hthymidine Hthymidine NNP cord-015569-vy49r1zd 73 25 or or CC cord-015569-vy49r1zd 73 26 Bromo Bromo NNP cord-015569-vy49r1zd 73 27 - - HYPH cord-015569-vy49r1zd 73 28 d d NNP cord-015569-vy49r1zd 73 29 - - HYPH cord-015569-vy49r1zd 73 30 uridine uridine JJ cord-015569-vy49r1zd 73 31 ( ( -LRB- cord-015569-vy49r1zd 73 32 BrdU BrdU NNP cord-015569-vy49r1zd 73 33 ) ) -RRB- cord-015569-vy49r1zd 73 34 incorporated incorporate VBD cord-015569-vy49r1zd 73 35 during during IN cord-015569-vy49r1zd 73 36 DNA dna NN cord-015569-vy49r1zd 73 37 synthesis synthesis NN cord-015569-vy49r1zd 73 38 . . . cord-015569-vy49r1zd 74 1 To to TO cord-015569-vy49r1zd 74 2 re re VB cord-015569-vy49r1zd 74 3 - - VB cord-015569-vy49r1zd 74 4 evaluate evaluate VB cord-015569-vy49r1zd 74 5 this this DT cord-015569-vy49r1zd 74 6 observed observed JJ cord-015569-vy49r1zd 74 7 lifetime lifetime NN cord-015569-vy49r1zd 74 8 of of IN cord-015569-vy49r1zd 74 9 taste taste NN cord-015569-vy49r1zd 74 10 bud bud NN cord-015569-vy49r1zd 74 11 cells cell NNS cord-015569-vy49r1zd 74 12 , , , cord-015569-vy49r1zd 74 13 we -PRON- PRP cord-015569-vy49r1zd 74 14 repeated repeat VBD cord-015569-vy49r1zd 74 15 the the DT cord-015569-vy49r1zd 74 16 analysis analysis NN cord-015569-vy49r1zd 74 17 of of IN cord-015569-vy49r1zd 74 18 lingual lingual JJ cord-015569-vy49r1zd 74 19 tissues tissue NNS cord-015569-vy49r1zd 74 20 of of IN cord-015569-vy49r1zd 74 21 mice mouse NNS cord-015569-vy49r1zd 74 22 after after IN cord-015569-vy49r1zd 74 23 incorporation incorporation NN cord-015569-vy49r1zd 74 24 of of IN cord-015569-vy49r1zd 74 25 ethynyl ethynyl NNP cord-015569-vy49r1zd 74 26 - - HYPH cord-015569-vy49r1zd 74 27 d d NN cord-015569-vy49r1zd 74 28 - - HYPH cord-015569-vy49r1zd 74 29 uridine uridine JJ cord-015569-vy49r1zd 74 30 ( ( -LRB- cord-015569-vy49r1zd 74 31 EdU edu NN cord-015569-vy49r1zd 74 32 ) ) -RRB- cord-015569-vy49r1zd 74 33 instead instead RB cord-015569-vy49r1zd 74 34 of of IN cord-015569-vy49r1zd 74 35 BrdU BrdU NNP cord-015569-vy49r1zd 74 36 , , , cord-015569-vy49r1zd 74 37 followed follow VBN cord-015569-vy49r1zd 74 38 by by IN cord-015569-vy49r1zd 74 39 detection detection NN cord-015569-vy49r1zd 74 40 of of IN cord-015569-vy49r1zd 74 41 EdU edu NN cord-015569-vy49r1zd 74 42 by by IN cord-015569-vy49r1zd 74 43 a a DT cord-015569-vy49r1zd 74 44 click click NN cord-015569-vy49r1zd 74 45 reaction reaction NN cord-015569-vy49r1zd 74 46 . . . cord-015569-vy49r1zd 75 1 We -PRON- PRP cord-015569-vy49r1zd 75 2 injected inject VBD cord-015569-vy49r1zd 75 3 EdU edu NN cord-015569-vy49r1zd 75 4 into into IN cord-015569-vy49r1zd 75 5 adult adult NN cord-015569-vy49r1zd 75 6 mice mouse NNS cord-015569-vy49r1zd 75 7 and and CC cord-015569-vy49r1zd 75 8 sacrificed sacrifice VBD cord-015569-vy49r1zd 75 9 them -PRON- PRP cord-015569-vy49r1zd 75 10 1 1 CD cord-015569-vy49r1zd 75 11 , , , cord-015569-vy49r1zd 75 12 3 3 CD cord-015569-vy49r1zd 75 13 , , , cord-015569-vy49r1zd 75 14 5 5 CD cord-015569-vy49r1zd 75 15 , , , cord-015569-vy49r1zd 75 16 6 6 CD cord-015569-vy49r1zd 75 17 , , , cord-015569-vy49r1zd 75 18 10 10 CD cord-015569-vy49r1zd 75 19 , , , cord-015569-vy49r1zd 75 20 15 15 CD cord-015569-vy49r1zd 75 21 , , , cord-015569-vy49r1zd 75 22 20 20 CD cord-015569-vy49r1zd 75 23 , , , cord-015569-vy49r1zd 75 24 25 25 CD cord-015569-vy49r1zd 75 25 , , , cord-015569-vy49r1zd 75 26 30 30 CD cord-015569-vy49r1zd 75 27 , , , cord-015569-vy49r1zd 75 28 35 35 CD cord-015569-vy49r1zd 75 29 , , , cord-015569-vy49r1zd 75 30 or or CC cord-015569-vy49r1zd 75 31 40 40 CD cord-015569-vy49r1zd 75 32 days day NNS cord-015569-vy49r1zd 75 33 later later RB cord-015569-vy49r1zd 75 34 . . . cord-015569-vy49r1zd 76 1 The the DT cord-015569-vy49r1zd 76 2 vallate vallate NN cord-015569-vy49r1zd 76 3 papillae papilla NNS cord-015569-vy49r1zd 76 4 were be VBD cord-015569-vy49r1zd 76 5 fixed fix VBN cord-015569-vy49r1zd 76 6 , , , cord-015569-vy49r1zd 76 7 cryo cryo NN cord-015569-vy49r1zd 76 8 - - HYPH cord-015569-vy49r1zd 76 9 sectioned section VBN cord-015569-vy49r1zd 76 10 , , , cord-015569-vy49r1zd 76 11 immunostained immunostaine VBN cord-015569-vy49r1zd 76 12 for for IN cord-015569-vy49r1zd 76 13 PLCb2 PLCb2 NNP cord-015569-vy49r1zd 76 14 ( ( -LRB- cord-015569-vy49r1zd 76 15 a a DT cord-015569-vy49r1zd 76 16 marker marker NN cord-015569-vy49r1zd 76 17 for for IN cord-015569-vy49r1zd 76 18 Type Type NNP cord-015569-vy49r1zd 76 19 II II NNP cord-015569-vy49r1zd 76 20 cells cell NNS cord-015569-vy49r1zd 76 21 ) ) -RRB- cord-015569-vy49r1zd 76 22 and and CC cord-015569-vy49r1zd 76 23 examined examine VBD cord-015569-vy49r1zd 76 24 with with IN cord-015569-vy49r1zd 76 25 a a DT cord-015569-vy49r1zd 76 26 confocal confocal JJ cord-015569-vy49r1zd 76 27 laser laser NN cord-015569-vy49r1zd 76 28 scanning scanning NN cord-015569-vy49r1zd 76 29 microscope microscope NN cord-015569-vy49r1zd 76 30 with with IN cord-015569-vy49r1zd 76 31 optical optical JJ cord-015569-vy49r1zd 76 32 sectioning sectioning NN cord-015569-vy49r1zd 76 33 at at IN cord-015569-vy49r1zd 76 34 2 2 CD cord-015569-vy49r1zd 76 35 lm lm NNP cord-015569-vy49r1zd 76 36 . . . cord-015569-vy49r1zd 77 1 Taste taste NN cord-015569-vy49r1zd 77 2 buds bud NNS cord-015569-vy49r1zd 77 3 were be VBD cord-015569-vy49r1zd 77 4 identified identify VBN cord-015569-vy49r1zd 77 5 in in IN cord-015569-vy49r1zd 77 6 DIC DIC NNP cord-015569-vy49r1zd 77 7 images image NNS cord-015569-vy49r1zd 77 8 captured capture VBN cord-015569-vy49r1zd 77 9 in in IN cord-015569-vy49r1zd 77 10 parallel parallel NN cord-015569-vy49r1zd 77 11 . . . cord-015569-vy49r1zd 78 1 Numerous numerous JJ cord-015569-vy49r1zd 78 2 cells cell NNS cord-015569-vy49r1zd 78 3 with with IN cord-015569-vy49r1zd 78 4 brightly brightly RB cord-015569-vy49r1zd 78 5 fluorescent fluorescent JJ cord-015569-vy49r1zd 78 6 nuclei nucleus NNS cord-015569-vy49r1zd 78 7 ( ( -LRB- cord-015569-vy49r1zd 78 8 EdU+ edu+ NN cord-015569-vy49r1zd 78 9 cells cell NNS cord-015569-vy49r1zd 78 10 ) ) -RRB- cord-015569-vy49r1zd 78 11 appeared appear VBD cord-015569-vy49r1zd 78 12 at at IN cord-015569-vy49r1zd 78 13 Day day NN cord-015569-vy49r1zd 78 14 1 1 CD cord-015569-vy49r1zd 78 15 near near RB cord-015569-vy49r1zd 78 16 and and CC cord-015569-vy49r1zd 78 17 within within IN cord-015569-vy49r1zd 78 18 taste taste NN cord-015569-vy49r1zd 78 19 buds bud NNS cord-015569-vy49r1zd 78 20 . . . cord-015569-vy49r1zd 79 1 The the DT cord-015569-vy49r1zd 79 2 number number NN cord-015569-vy49r1zd 79 3 of of IN cord-015569-vy49r1zd 79 4 those those DT cord-015569-vy49r1zd 79 5 cells cell NNS cord-015569-vy49r1zd 79 6 declined decline VBD cord-015569-vy49r1zd 79 7 rapidly rapidly RB cord-015569-vy49r1zd 79 8 toward toward IN cord-015569-vy49r1zd 79 9 Day Day NNP cord-015569-vy49r1zd 79 10 10 10 CD cord-015569-vy49r1zd 79 11 . . . cord-015569-vy49r1zd 80 1 However however RB cord-015569-vy49r1zd 80 2 , , , cord-015569-vy49r1zd 80 3 among among IN cord-015569-vy49r1zd 80 4 Type Type NNP cord-015569-vy49r1zd 80 5 II II NNP cord-015569-vy49r1zd 80 6 cells cell NNS cord-015569-vy49r1zd 80 7 , , , cord-015569-vy49r1zd 80 8 very very RB cord-015569-vy49r1zd 80 9 few few JJ cord-015569-vy49r1zd 80 10 appeared appear VBD cord-015569-vy49r1zd 80 11 to to TO cord-015569-vy49r1zd 80 12 be be VB cord-015569-vy49r1zd 80 13 EdU+ edu+ JJ cord-015569-vy49r1zd 80 14 at at IN cord-015569-vy49r1zd 80 15 Day day NN cord-015569-vy49r1zd 80 16 1 1 CD cord-015569-vy49r1zd 80 17 . . . cord-015569-vy49r1zd 81 1 The the DT cord-015569-vy49r1zd 81 2 number number NN cord-015569-vy49r1zd 81 3 of of IN cord-015569-vy49r1zd 81 4 EdU+ EdU+ NNP cord-015569-vy49r1zd 81 5 Type Type NNP cord-015569-vy49r1zd 81 6 II II NNP cord-015569-vy49r1zd 81 7 cells cell NNS cord-015569-vy49r1zd 81 8 increased increase VBD cord-015569-vy49r1zd 81 9 at at IN cord-015569-vy49r1zd 81 10 Day day NN cord-015569-vy49r1zd 81 11 3 3 CD cord-015569-vy49r1zd 81 12 , , , cord-015569-vy49r1zd 81 13 showed show VBD cord-015569-vy49r1zd 81 14 a a DT cord-015569-vy49r1zd 81 15 broad broad JJ cord-015569-vy49r1zd 81 16 peak peak NN cord-015569-vy49r1zd 81 17 around around IN cord-015569-vy49r1zd 81 18 Day Day NNP cord-015569-vy49r1zd 81 19 10 10 CD cord-015569-vy49r1zd 81 20 , , , cord-015569-vy49r1zd 81 21 and and CC cord-015569-vy49r1zd 81 22 then then RB cord-015569-vy49r1zd 81 23 declined decline VBD cord-015569-vy49r1zd 81 24 . . . cord-015569-vy49r1zd 82 1 Occasional occasional JJ cord-015569-vy49r1zd 82 2 EdU+ EdU+ NNP cord-015569-vy49r1zd 82 3 Type Type NNP cord-015569-vy49r1zd 82 4 II II NNP cord-015569-vy49r1zd 82 5 cells cell NNS cord-015569-vy49r1zd 82 6 were be VBD cord-015569-vy49r1zd 82 7 still still RB cord-015569-vy49r1zd 82 8 detected detect VBN cord-015569-vy49r1zd 82 9 at at IN cord-015569-vy49r1zd 82 10 Day day NN cord-015569-vy49r1zd 82 11 40 40 CD cord-015569-vy49r1zd 82 12 . . . cord-015569-vy49r1zd 83 1 Because because IN cord-015569-vy49r1zd 83 2 labeling labeling NN cord-015569-vy49r1zd 83 3 of of IN cord-015569-vy49r1zd 83 4 DNA dna NN cord-015569-vy49r1zd 83 5 with with IN cord-015569-vy49r1zd 83 6 EdU edu NN cord-015569-vy49r1zd 83 7 is be VBZ cord-015569-vy49r1zd 83 8 much much RB cord-015569-vy49r1zd 83 9 faster fast JJR cord-015569-vy49r1zd 83 10 , , , cord-015569-vy49r1zd 83 11 brighter bright JJR cord-015569-vy49r1zd 83 12 and and CC cord-015569-vy49r1zd 83 13 more more RBR cord-015569-vy49r1zd 83 14 consistent consistent JJ cord-015569-vy49r1zd 83 15 than than IN cord-015569-vy49r1zd 83 16 with with IN cord-015569-vy49r1zd 83 17 BrdU BrdU NNP cord-015569-vy49r1zd 83 18 , , , cord-015569-vy49r1zd 83 19 this this DT cord-015569-vy49r1zd 83 20 method method NN cord-015569-vy49r1zd 83 21 will will MD cord-015569-vy49r1zd 83 22 be be VB cord-015569-vy49r1zd 83 23 useful useful JJ cord-015569-vy49r1zd 83 24 to to TO cord-015569-vy49r1zd 83 25 study study VB cord-015569-vy49r1zd 83 26 proliferating proliferate VBG cord-015569-vy49r1zd 83 27 cells cell NNS cord-015569-vy49r1zd 83 28 in in IN cord-015569-vy49r1zd 83 29 taste taste NN cord-015569-vy49r1zd 83 30 buds bud NNS cord-015569-vy49r1zd 83 31 . . . cord-015569-vy49r1zd 84 1 By by IN cord-015569-vy49r1zd 84 2 combining combine VBG cord-015569-vy49r1zd 84 3 EdU edu NN cord-015569-vy49r1zd 84 4 labeling labeling NN cord-015569-vy49r1zd 84 5 and and CC cord-015569-vy49r1zd 84 6 immunstaining immunstaine VBG cord-015569-vy49r1zd 84 7 for for IN cord-015569-vy49r1zd 84 8 approapriate approapriate NN cord-015569-vy49r1zd 84 9 markers marker NNS cord-015569-vy49r1zd 84 10 , , , cord-015569-vy49r1zd 84 11 the the DT cord-015569-vy49r1zd 84 12 longevity longevity NN cord-015569-vy49r1zd 84 13 of of IN cord-015569-vy49r1zd 84 14 taste taste NN cord-015569-vy49r1zd 84 15 cell cell NN cord-015569-vy49r1zd 84 16 types type NNS cord-015569-vy49r1zd 84 17 can can MD cord-015569-vy49r1zd 84 18 be be VB cord-015569-vy49r1zd 84 19 examined examine VBN cord-015569-vy49r1zd 84 20 . . . cord-015569-vy49r1zd 85 1 Adiponectin Adiponectin NNP cord-015569-vy49r1zd 85 2 is be VBZ cord-015569-vy49r1zd 85 3 a a DT cord-015569-vy49r1zd 85 4 white white JJ cord-015569-vy49r1zd 85 5 adipose adipose JJ cord-015569-vy49r1zd 85 6 protein protein NN cord-015569-vy49r1zd 85 7 that that WDT cord-015569-vy49r1zd 85 8 plays play VBZ cord-015569-vy49r1zd 85 9 important important JJ cord-015569-vy49r1zd 85 10 roles role NNS cord-015569-vy49r1zd 85 11 in in IN cord-015569-vy49r1zd 85 12 glucose glucose NN cord-015569-vy49r1zd 85 13 homeostasis homeostasis NN cord-015569-vy49r1zd 85 14 and and CC cord-015569-vy49r1zd 85 15 lipid lipid NN cord-015569-vy49r1zd 85 16 metabolism metabolism NN cord-015569-vy49r1zd 85 17 and and CC cord-015569-vy49r1zd 85 18 is be VBZ cord-015569-vy49r1zd 85 19 involved involve VBN cord-015569-vy49r1zd 85 20 in in IN cord-015569-vy49r1zd 85 21 cell cell NN cord-015569-vy49r1zd 85 22 proliferation proliferation NN cord-015569-vy49r1zd 85 23 and and CC cord-015569-vy49r1zd 85 24 differentiation differentiation NN cord-015569-vy49r1zd 85 25 . . . cord-015569-vy49r1zd 86 1 The the DT cord-015569-vy49r1zd 86 2 function function NN cord-015569-vy49r1zd 86 3 of of IN cord-015569-vy49r1zd 86 4 adiponectin adiponectin NN cord-015569-vy49r1zd 86 5 is be VBZ cord-015569-vy49r1zd 86 6 mediated mediate VBN cord-015569-vy49r1zd 86 7 by by IN cord-015569-vy49r1zd 86 8 its -PRON- PRP$ cord-015569-vy49r1zd 86 9 receptors receptor NNS cord-015569-vy49r1zd 86 10 ( ( -LRB- cord-015569-vy49r1zd 86 11 AdipoR1 adipor1 NN cord-015569-vy49r1zd 86 12 and and CC cord-015569-vy49r1zd 86 13 AdipoR2 adipor2 NN cord-015569-vy49r1zd 86 14 ) ) -RRB- cord-015569-vy49r1zd 86 15 , , , cord-015569-vy49r1zd 86 16 which which WDT cord-015569-vy49r1zd 86 17 have have VBP cord-015569-vy49r1zd 86 18 different different JJ cord-015569-vy49r1zd 86 19 expression expression NN cord-015569-vy49r1zd 86 20 patterns pattern NNS cord-015569-vy49r1zd 86 21 . . . cord-015569-vy49r1zd 87 1 In in IN cord-015569-vy49r1zd 87 2 the the DT cord-015569-vy49r1zd 87 3 gustatory gustatory JJ cord-015569-vy49r1zd 87 4 system system NN cord-015569-vy49r1zd 87 5 , , , cord-015569-vy49r1zd 87 6 adiponectin adiponectin NN cord-015569-vy49r1zd 87 7 is be VBZ cord-015569-vy49r1zd 87 8 contained contain VBN cord-015569-vy49r1zd 87 9 in in IN cord-015569-vy49r1zd 87 10 the the DT cord-015569-vy49r1zd 87 11 saliva saliva NN cord-015569-vy49r1zd 87 12 ; ; : cord-015569-vy49r1zd 87 13 however however RB cord-015569-vy49r1zd 87 14 , , , cord-015569-vy49r1zd 87 15 the the DT cord-015569-vy49r1zd 87 16 function function NN cord-015569-vy49r1zd 87 17 of of IN cord-015569-vy49r1zd 87 18 adiponectin adiponectin NN cord-015569-vy49r1zd 87 19 signaling signal VBG cord-015569-vy49r1zd 87 20 in in IN cord-015569-vy49r1zd 87 21 gustatory gustatory JJ cord-015569-vy49r1zd 87 22 tissues tissue NNS cord-015569-vy49r1zd 87 23 has have VBZ cord-015569-vy49r1zd 87 24 not not RB cord-015569-vy49r1zd 87 25 been be VBN cord-015569-vy49r1zd 87 26 elucidated elucidate VBN cord-015569-vy49r1zd 87 27 yet yet RB cord-015569-vy49r1zd 87 28 . . . cord-015569-vy49r1zd 88 1 Therefore therefore RB cord-015569-vy49r1zd 88 2 , , , cord-015569-vy49r1zd 88 3 we -PRON- PRP cord-015569-vy49r1zd 88 4 have have VBP cord-015569-vy49r1zd 88 5 examined examine VBN cord-015569-vy49r1zd 88 6 the the DT cord-015569-vy49r1zd 88 7 expression expression NN cord-015569-vy49r1zd 88 8 patterns pattern NNS cord-015569-vy49r1zd 88 9 of of IN cord-015569-vy49r1zd 88 10 AdipoR1 adipor1 NN cord-015569-vy49r1zd 88 11 and and CC cord-015569-vy49r1zd 88 12 AdipoR2 adipor2 NN cord-015569-vy49r1zd 88 13 in in IN cord-015569-vy49r1zd 88 14 mouse mouse NN cord-015569-vy49r1zd 88 15 gustatory gustatory JJ cord-015569-vy49r1zd 88 16 tissues tissue NNS cord-015569-vy49r1zd 88 17 . . . cord-015569-vy49r1zd 89 1 Reverse reverse JJ cord-015569-vy49r1zd 89 2 transcription transcription NN cord-015569-vy49r1zd 89 3 polymerase polymerase NN cord-015569-vy49r1zd 89 4 chain chain NN cord-015569-vy49r1zd 89 5 reaction reaction NN cord-015569-vy49r1zd 89 6 assays assay NNS cord-015569-vy49r1zd 89 7 have have VBP cord-015569-vy49r1zd 89 8 revealed reveal VBN cord-015569-vy49r1zd 89 9 that that DT cord-015569-vy49r1zd 89 10 AdipoR1 adipor1 NN cord-015569-vy49r1zd 89 11 and and CC cord-015569-vy49r1zd 90 1 AdipoR2 adipor2 LS cord-015569-vy49r1zd 90 2 mRNAs mrnas CD cord-015569-vy49r1zd 90 3 were be VBD cord-015569-vy49r1zd 90 4 expressed express VBN cord-015569-vy49r1zd 90 5 in in IN cord-015569-vy49r1zd 90 6 the the DT cord-015569-vy49r1zd 90 7 circumvallate circumvallate JJ cord-015569-vy49r1zd 90 8 papillae papilla NNS cord-015569-vy49r1zd 90 9 . . . cord-015569-vy49r1zd 91 1 Using use VBG cord-015569-vy49r1zd 91 2 immunohistochemistry immunohistochemistry NN cord-015569-vy49r1zd 91 3 , , , cord-015569-vy49r1zd 91 4 the the DT cord-015569-vy49r1zd 91 5 anti anti NN cord-015569-vy49r1zd 91 6 - - JJ cord-015569-vy49r1zd 91 7 AdipoR1 adipor1 JJ cord-015569-vy49r1zd 91 8 antibody antibody NN cord-015569-vy49r1zd 91 9 labeled label VBN cord-015569-vy49r1zd 91 10 at at IN cord-015569-vy49r1zd 91 11 the the DT cord-015569-vy49r1zd 91 12 taste taste NN cord-015569-vy49r1zd 91 13 hairs hair NNS cord-015569-vy49r1zd 91 14 in in IN cord-015569-vy49r1zd 91 15 the the DT cord-015569-vy49r1zd 91 16 fungiform fungiform NN cord-015569-vy49r1zd 91 17 , , , cord-015569-vy49r1zd 91 18 foliate foliate NN cord-015569-vy49r1zd 91 19 and and CC cord-015569-vy49r1zd 91 20 circumvallate circumvallate JJ cord-015569-vy49r1zd 91 21 papillae papilla NNS cord-015569-vy49r1zd 91 22 . . . cord-015569-vy49r1zd 92 1 Double double JJ cord-015569-vy49r1zd 92 2 - - HYPH cord-015569-vy49r1zd 92 3 labeling labeling NN cord-015569-vy49r1zd 92 4 experiments experiment NNS cord-015569-vy49r1zd 92 5 have have VBP cord-015569-vy49r1zd 92 6 demonstrated demonstrate VBN cord-015569-vy49r1zd 92 7 an an DT cord-015569-vy49r1zd 92 8 expression expression NN cord-015569-vy49r1zd 92 9 pattern pattern NN cord-015569-vy49r1zd 92 10 of of IN cord-015569-vy49r1zd 92 11 AdipoR1-positive AdipoR1-positive NNP cord-015569-vy49r1zd 92 12 cells cell NNS cord-015569-vy49r1zd 92 13 in in IN cord-015569-vy49r1zd 92 14 a a DT cord-015569-vy49r1zd 92 15 subset subset NN cord-015569-vy49r1zd 92 16 of of IN cord-015569-vy49r1zd 92 17 basal basal NN cord-015569-vy49r1zd 92 18 cells cell NNS cord-015569-vy49r1zd 92 19 within within IN cord-015569-vy49r1zd 92 20 the the DT cord-015569-vy49r1zd 92 21 taste taste NN cord-015569-vy49r1zd 92 22 buds bud NNS cord-015569-vy49r1zd 92 23 and and CC cord-015569-vy49r1zd 92 24 extragemmal extragemmal JJ cord-015569-vy49r1zd 92 25 epithelium epithelium NN cord-015569-vy49r1zd 92 26 cells cell NNS cord-015569-vy49r1zd 92 27 to to IN cord-015569-vy49r1zd 92 28 marker marker NN cord-015569-vy49r1zd 92 29 proteins protein NNS cord-015569-vy49r1zd 92 30 for for IN cord-015569-vy49r1zd 92 31 taste taste NN cord-015569-vy49r1zd 92 32 cell cell NN cord-015569-vy49r1zd 92 33 types type NNS cord-015569-vy49r1zd 92 34 ( ( -LRB- cord-015569-vy49r1zd 92 35 including include VBG cord-015569-vy49r1zd 92 36 types type NNS cord-015569-vy49r1zd 92 37 I -PRON- PRP cord-015569-vy49r1zd 92 38 , , , cord-015569-vy49r1zd 92 39 II II NNP cord-015569-vy49r1zd 92 40 , , , cord-015569-vy49r1zd 92 41 III III NNP cord-015569-vy49r1zd 92 42 , , , cord-015569-vy49r1zd 92 43 and and CC cord-015569-vy49r1zd 92 44 basal basal NN cord-015569-vy49r1zd 92 45 cells cell NNS cord-015569-vy49r1zd 92 46 ) ) -RRB- cord-015569-vy49r1zd 92 47 . . . cord-015569-vy49r1zd 93 1 For for IN cord-015569-vy49r1zd 93 2 the the DT cord-015569-vy49r1zd 93 3 marker marker NN cord-015569-vy49r1zd 93 4 proteins protein NNS cord-015569-vy49r1zd 93 5 analyzed analyze VBN cord-015569-vy49r1zd 93 6 , , , cord-015569-vy49r1zd 93 7 only only RB cord-015569-vy49r1zd 93 8 Shh Shh NNP cord-015569-vy49r1zd 93 9 was be VBD cord-015569-vy49r1zd 93 10 co co VBN cord-015569-vy49r1zd 93 11 - - VBN cord-015569-vy49r1zd 93 12 expressed express VBN cord-015569-vy49r1zd 93 13 with with IN cord-015569-vy49r1zd 93 14 AdipoR1 adipor1 NN cord-015569-vy49r1zd 93 15 in in IN cord-015569-vy49r1zd 93 16 a a DT cord-015569-vy49r1zd 93 17 subset subset NN cord-015569-vy49r1zd 93 18 of of IN cord-015569-vy49r1zd 93 19 basal basal NN cord-015569-vy49r1zd 93 20 cells cell NNS cord-015569-vy49r1zd 93 21 within within IN cord-015569-vy49r1zd 93 22 the the DT cord-015569-vy49r1zd 93 23 taste taste NN cord-015569-vy49r1zd 93 24 buds bud NNS cord-015569-vy49r1zd 93 25 in in IN cord-015569-vy49r1zd 93 26 the the DT cord-015569-vy49r1zd 93 27 circumvallate circumvallate JJ cord-015569-vy49r1zd 93 28 papillae papilla NNS cord-015569-vy49r1zd 93 29 . . . cord-015569-vy49r1zd 94 1 These these DT cord-015569-vy49r1zd 94 2 results result NNS cord-015569-vy49r1zd 94 3 show show VBP cord-015569-vy49r1zd 94 4 that that IN cord-015569-vy49r1zd 94 5 AdipoR1 adipor1 NN cord-015569-vy49r1zd 94 6 at at IN cord-015569-vy49r1zd 94 7 taste taste NN cord-015569-vy49r1zd 94 8 hairs hair NNS cord-015569-vy49r1zd 94 9 in in IN cord-015569-vy49r1zd 94 10 gustatory gustatory JJ cord-015569-vy49r1zd 94 11 tissues tissue NNS cord-015569-vy49r1zd 94 12 may may MD cord-015569-vy49r1zd 94 13 detect detect VB cord-015569-vy49r1zd 94 14 saliva saliva NN cord-015569-vy49r1zd 94 15 adiponectin adiponectin NN cord-015569-vy49r1zd 94 16 and and CC cord-015569-vy49r1zd 94 17 may may MD cord-015569-vy49r1zd 94 18 play play VB cord-015569-vy49r1zd 94 19 a a DT cord-015569-vy49r1zd 94 20 role role NN cord-015569-vy49r1zd 94 21 in in IN cord-015569-vy49r1zd 94 22 taste taste NN cord-015569-vy49r1zd 94 23 sensing sensing NN cord-015569-vy49r1zd 94 24 in in IN cord-015569-vy49r1zd 94 25 the the DT cord-015569-vy49r1zd 94 26 taste taste NN cord-015569-vy49r1zd 94 27 buds bud NNS cord-015569-vy49r1zd 94 28 . . . cord-015569-vy49r1zd 95 1 In in IN cord-015569-vy49r1zd 95 2 addition addition NN cord-015569-vy49r1zd 95 3 , , , cord-015569-vy49r1zd 95 4 AdipoR1 adipor1 NN cord-015569-vy49r1zd 95 5 may may MD cord-015569-vy49r1zd 95 6 play play VB cord-015569-vy49r1zd 95 7 a a DT cord-015569-vy49r1zd 95 8 role role NN cord-015569-vy49r1zd 95 9 in in IN cord-015569-vy49r1zd 95 10 cell cell NN cord-015569-vy49r1zd 95 11 proliferation proliferation NN cord-015569-vy49r1zd 95 12 and and CC cord-015569-vy49r1zd 95 13 differentiation differentiation NN cord-015569-vy49r1zd 95 14 for for IN cord-015569-vy49r1zd 95 15 the the DT cord-015569-vy49r1zd 95 16 Shh Shh NNP cord-015569-vy49r1zd 95 17 and and CC cord-015569-vy49r1zd 95 18 AdipoR1 adipor1 NN cord-015569-vy49r1zd 96 1 expressing express VBG cord-015569-vy49r1zd 96 2 basal basal NN cord-015569-vy49r1zd 96 3 cells cell NNS cord-015569-vy49r1zd 96 4 within within IN cord-015569-vy49r1zd 96 5 the the DT cord-015569-vy49r1zd 96 6 taste taste NN cord-015569-vy49r1zd 96 7 buds bud NNS cord-015569-vy49r1zd 96 8 . . . cord-015569-vy49r1zd 97 1 Mash1 Mash1 NNP cord-015569-vy49r1zd 97 2 is be VBZ cord-015569-vy49r1zd 97 3 expressed express VBN cord-015569-vy49r1zd 97 4 in in IN cord-015569-vy49r1zd 97 5 subsets subset NNS cord-015569-vy49r1zd 97 6 of of IN cord-015569-vy49r1zd 97 7 neuronal neuronal JJ cord-015569-vy49r1zd 97 8 precursors precursor NNS cord-015569-vy49r1zd 97 9 in in IN cord-015569-vy49r1zd 97 10 both both CC cord-015569-vy49r1zd 97 11 the the DT cord-015569-vy49r1zd 97 12 central central JJ cord-015569-vy49r1zd 97 13 nervous nervous JJ cord-015569-vy49r1zd 97 14 system system NN cord-015569-vy49r1zd 97 15 and and CC cord-015569-vy49r1zd 97 16 the the DT cord-015569-vy49r1zd 97 17 peripheral peripheral JJ cord-015569-vy49r1zd 97 18 nervous nervous JJ cord-015569-vy49r1zd 97 19 system system NN cord-015569-vy49r1zd 97 20 . . . cord-015569-vy49r1zd 98 1 However however RB cord-015569-vy49r1zd 98 2 , , , cord-015569-vy49r1zd 98 3 involvement involvement NN cord-015569-vy49r1zd 98 4 of of IN cord-015569-vy49r1zd 98 5 Mash1 Mash1 NNS cord-015569-vy49r1zd 98 6 in in IN cord-015569-vy49r1zd 98 7 taste taste NN cord-015569-vy49r1zd 98 8 bud bud NN cord-015569-vy49r1zd 98 9 cell cell NN cord-015569-vy49r1zd 98 10 differentiation differentiation NN cord-015569-vy49r1zd 98 11 remained remain VBD cord-015569-vy49r1zd 98 12 to to TO cord-015569-vy49r1zd 98 13 be be VB cord-015569-vy49r1zd 98 14 demonstrated demonstrate VBN cord-015569-vy49r1zd 98 15 . . . cord-015569-vy49r1zd 99 1 In in IN cord-015569-vy49r1zd 99 2 the the DT cord-015569-vy49r1zd 99 3 present present JJ cord-015569-vy49r1zd 99 4 study study NN cord-015569-vy49r1zd 99 5 , , , cord-015569-vy49r1zd 99 6 to to TO cord-015569-vy49r1zd 99 7 begin begin VB cord-015569-vy49r1zd 99 8 to to TO cord-015569-vy49r1zd 99 9 understand understand VB cord-015569-vy49r1zd 99 10 the the DT cord-015569-vy49r1zd 99 11 mechanisms mechanism NNS cord-015569-vy49r1zd 99 12 that that WDT cord-015569-vy49r1zd 99 13 regulate regulate VBP cord-015569-vy49r1zd 99 14 taste taste NN cord-015569-vy49r1zd 99 15 bud bud NN cord-015569-vy49r1zd 99 16 cell cell NN cord-015569-vy49r1zd 99 17 differentiation differentiation NN cord-015569-vy49r1zd 99 18 , , , cord-015569-vy49r1zd 99 19 we -PRON- PRP cord-015569-vy49r1zd 99 20 have have VBP cord-015569-vy49r1zd 99 21 investigated investigate VBN cord-015569-vy49r1zd 99 22 the the DT cord-015569-vy49r1zd 99 23 role role NN cord-015569-vy49r1zd 99 24 of of IN cord-015569-vy49r1zd 99 25 Mash1 Mash1 NNS cord-015569-vy49r1zd 99 26 in in IN cord-015569-vy49r1zd 99 27 regulating regulate VBG cord-015569-vy49r1zd 99 28 taste taste NN cord-015569-vy49r1zd 99 29 bud bud NN cord-015569-vy49r1zd 99 30 cell cell NN cord-015569-vy49r1zd 99 31 differentiation differentiation NN cord-015569-vy49r1zd 99 32 using use VBG cord-015569-vy49r1zd 99 33 Mash1 Mash1 NNS cord-015569-vy49r1zd 99 34 KO KO NNP cord-015569-vy49r1zd 99 35 mice mouse NNS cord-015569-vy49r1zd 99 36 and and CC cord-015569-vy49r1zd 99 37 forced force VBN cord-015569-vy49r1zd 99 38 expression expression NN cord-015569-vy49r1zd 99 39 of of IN cord-015569-vy49r1zd 99 40 Mash1 Mash1 NNS cord-015569-vy49r1zd 99 41 in in IN cord-015569-vy49r1zd 99 42 lingual lingual JJ cord-015569-vy49r1zd 99 43 epithelial epithelial JJ cord-015569-vy49r1zd 99 44 cells cell NNS cord-015569-vy49r1zd 99 45 . . . cord-015569-vy49r1zd 100 1 In in IN cord-015569-vy49r1zd 100 2 Mash1 Mash1 NNS cord-015569-vy49r1zd 100 3 KO KO NNP cord-015569-vy49r1zd 100 4 mice mouse NNS cord-015569-vy49r1zd 100 5 , , , cord-015569-vy49r1zd 100 6 AADC AADC NNP cord-015569-vy49r1zd 100 7 - - HYPH cord-015569-vy49r1zd 100 8 IR IR NNP cord-015569-vy49r1zd 100 9 cells cell NNS cord-015569-vy49r1zd 100 10 are be VBP cord-015569-vy49r1zd 100 11 missing miss VBG cord-015569-vy49r1zd 100 12 both both DT cord-015569-vy49r1zd 100 13 in in IN cord-015569-vy49r1zd 100 14 the the DT cord-015569-vy49r1zd 100 15 Mash1 Mash1 NNP cord-015569-vy49r1zd 100 16 mutant mutant JJ cord-015569-vy49r1zd 100 17 circumvallate circumvallate NN cord-015569-vy49r1zd 100 18 papilla papilla NN cord-015569-vy49r1zd 100 19 epithelium epithelium NN cord-015569-vy49r1zd 100 20 and and CC cord-015569-vy49r1zd 100 21 in in IN cord-015569-vy49r1zd 100 22 the the DT cord-015569-vy49r1zd 100 23 taste taste NN cord-015569-vy49r1zd 100 24 buds bud NNS cord-015569-vy49r1zd 100 25 of of IN cord-015569-vy49r1zd 100 26 soft soft JJ cord-015569-vy49r1zd 100 27 palate palate NN cord-015569-vy49r1zd 100 28 . . . cord-015569-vy49r1zd 101 1 In in IN cord-015569-vy49r1zd 101 2 Mash1 Mash1 NNS cord-015569-vy49r1zd 101 3 KO KO NNP cord-015569-vy49r1zd 101 4 / / SYM cord-015569-vy49r1zd 101 5 GAD67-GFP GAD67-GFP NNP cord-015569-vy49r1zd 101 6 mice mouse NNS cord-015569-vy49r1zd 101 7 , , , cord-015569-vy49r1zd 101 8 GFP gfp NN cord-015569-vy49r1zd 101 9 - - HYPH cord-015569-vy49r1zd 101 10 positive positive JJ cord-015569-vy49r1zd 101 11 cells cell NNS cord-015569-vy49r1zd 101 12 ( ( -LRB- cord-015569-vy49r1zd 101 13 GAD67 gad67 NN cord-015569-vy49r1zd 101 14 expressing express VBG cord-015569-vy49r1zd 101 15 type type NN cord-015569-vy49r1zd 101 16 III iii CD cord-015569-vy49r1zd 101 17 cells cell NNS cord-015569-vy49r1zd 101 18 ) ) -RRB- cord-015569-vy49r1zd 101 19 are be VBP cord-015569-vy49r1zd 101 20 also also RB cord-015569-vy49r1zd 101 21 missing miss VBG cord-015569-vy49r1zd 101 22 in in IN cord-015569-vy49r1zd 101 23 the the DT cord-015569-vy49r1zd 101 24 taste taste NN cord-015569-vy49r1zd 101 25 buds bud NNS cord-015569-vy49r1zd 101 26 of of IN cord-015569-vy49r1zd 101 27 soft soft JJ cord-015569-vy49r1zd 101 28 palate palate NN cord-015569-vy49r1zd 101 29 . . . cord-015569-vy49r1zd 102 1 On on IN cord-015569-vy49r1zd 102 2 the the DT cord-015569-vy49r1zd 102 3 other other JJ cord-015569-vy49r1zd 102 4 hand hand NN cord-015569-vy49r1zd 102 5 , , , cord-015569-vy49r1zd 102 6 Gustducin Gustducin NNP cord-015569-vy49r1zd 102 7 , , , cord-015569-vy49r1zd 102 8 a a DT cord-015569-vy49r1zd 102 9 type type NN cord-015569-vy49r1zd 102 10 II ii CD cord-015569-vy49r1zd 102 11 cell cell NN cord-015569-vy49r1zd 102 12 marker marker NN cord-015569-vy49r1zd 102 13 of of IN cord-015569-vy49r1zd 102 14 taste taste NN cord-015569-vy49r1zd 102 15 bud bud NN cord-015569-vy49r1zd 102 16 , , , cord-015569-vy49r1zd 102 17 is be VBZ cord-015569-vy49r1zd 102 18 expressed express VBN cord-015569-vy49r1zd 102 19 in in IN cord-015569-vy49r1zd 102 20 soft soft JJ cord-015569-vy49r1zd 102 21 palate palate NN cord-015569-vy49r1zd 102 22 taste taste NN cord-015569-vy49r1zd 102 23 buds bud NNS cord-015569-vy49r1zd 102 24 in in IN cord-015569-vy49r1zd 102 25 Mash1 Mash1 NNP cord-015569-vy49r1zd 102 26 mutant mutant JJ cord-015569-vy49r1zd 102 27 mice mouse NNS cord-015569-vy49r1zd 102 28 . . . cord-015569-vy49r1zd 103 1 These these DT cord-015569-vy49r1zd 103 2 results result NNS cord-015569-vy49r1zd 103 3 suggest suggest VBP cord-015569-vy49r1zd 103 4 that that IN cord-015569-vy49r1zd 103 5 Mash1 Mash1 NNP cord-015569-vy49r1zd 103 6 plays play VBZ cord-015569-vy49r1zd 103 7 an an DT cord-015569-vy49r1zd 103 8 important important JJ cord-015569-vy49r1zd 103 9 role role NN cord-015569-vy49r1zd 103 10 for for IN cord-015569-vy49r1zd 103 11 expression expression NN cord-015569-vy49r1zd 103 12 of of IN cord-015569-vy49r1zd 103 13 AADC AADC NNP cord-015569-vy49r1zd 103 14 and and CC cord-015569-vy49r1zd 103 15 GAD67 GAD67 NNP cord-015569-vy49r1zd 103 16 in in IN cord-015569-vy49r1zd 103 17 type type NN cord-015569-vy49r1zd 103 18 III iii CD cord-015569-vy49r1zd 103 19 cells cell NNS cord-015569-vy49r1zd 103 20 in in IN cord-015569-vy49r1zd 103 21 taste taste NN cord-015569-vy49r1zd 103 22 buds bud NNS cord-015569-vy49r1zd 103 23 . . . cord-015569-vy49r1zd 104 1 Taste taste VB cord-015569-vy49r1zd 104 2 receptor receptor NN cord-015569-vy49r1zd 104 3 cells cell NNS cord-015569-vy49r1zd 104 4 are be VBP cord-015569-vy49r1zd 104 5 epithelial epithelial JJ cord-015569-vy49r1zd 104 6 in in IN cord-015569-vy49r1zd 104 7 sense sense NN cord-015569-vy49r1zd 104 8 that that IN cord-015569-vy49r1zd 104 9 they -PRON- PRP cord-015569-vy49r1zd 104 10 have have VBP cord-015569-vy49r1zd 104 11 a a DT cord-015569-vy49r1zd 104 12 limited limited JJ cord-015569-vy49r1zd 104 13 life life NN cord-015569-vy49r1zd 104 14 span span NN cord-015569-vy49r1zd 104 15 and and CC cord-015569-vy49r1zd 104 16 therefore therefore RB cord-015569-vy49r1zd 104 17 must must MD cord-015569-vy49r1zd 104 18 be be VB cord-015569-vy49r1zd 104 19 replaced replace VBN cord-015569-vy49r1zd 104 20 to to TO cord-015569-vy49r1zd 104 21 maintain maintain VB cord-015569-vy49r1zd 104 22 the the DT cord-015569-vy49r1zd 104 23 structure structure NN cord-015569-vy49r1zd 104 24 of of IN cord-015569-vy49r1zd 104 25 the the DT cord-015569-vy49r1zd 104 26 epithelium epithelium NN cord-015569-vy49r1zd 104 27 . . . cord-015569-vy49r1zd 105 1 Therefore therefore RB cord-015569-vy49r1zd 105 2 gustatory gustatory JJ cord-015569-vy49r1zd 105 3 nerves nerve NNS cord-015569-vy49r1zd 105 4 need need VBP cord-015569-vy49r1zd 105 5 to to TO cord-015569-vy49r1zd 105 6 make make VB cord-015569-vy49r1zd 105 7 synapse synapse NN cord-015569-vy49r1zd 105 8 with with IN cord-015569-vy49r1zd 105 9 appropriate appropriate JJ cord-015569-vy49r1zd 105 10 taste taste NN cord-015569-vy49r1zd 105 11 receptor receptor NN cord-015569-vy49r1zd 105 12 cells cell NNS cord-015569-vy49r1zd 105 13 . . . cord-015569-vy49r1zd 106 1 However however RB cord-015569-vy49r1zd 106 2 , , , cord-015569-vy49r1zd 106 3 mechanism mechanism NN cord-015569-vy49r1zd 106 4 of of IN cord-015569-vy49r1zd 106 5 recognition recognition NN cord-015569-vy49r1zd 106 6 of of IN cord-015569-vy49r1zd 106 7 taste taste NN cord-015569-vy49r1zd 106 8 receptor receptor NN cord-015569-vy49r1zd 106 9 cells cell NNS cord-015569-vy49r1zd 106 10 which which WDT cord-015569-vy49r1zd 106 11 express express VBP cord-015569-vy49r1zd 106 12 appropriate appropriate JJ cord-015569-vy49r1zd 106 13 taste taste NN cord-015569-vy49r1zd 106 14 receptor receptor NN cord-015569-vy49r1zd 106 15 is be VBZ cord-015569-vy49r1zd 106 16 still still RB cord-015569-vy49r1zd 106 17 unknown unknown JJ cord-015569-vy49r1zd 106 18 . . . cord-015569-vy49r1zd 107 1 The the DT cord-015569-vy49r1zd 107 2 cadherin cadherin NN cord-015569-vy49r1zd 107 3 superfamily superfamily NN cord-015569-vy49r1zd 107 4 of of IN cord-015569-vy49r1zd 107 5 cell cell NN cord-015569-vy49r1zd 107 6 - - HYPH cord-015569-vy49r1zd 107 7 cell cell NN cord-015569-vy49r1zd 107 8 adhesion adhesion NN cord-015569-vy49r1zd 107 9 molecules molecule NNS cord-015569-vy49r1zd 107 10 controls control VBZ cord-015569-vy49r1zd 107 11 a a DT cord-015569-vy49r1zd 107 12 series series NN cord-015569-vy49r1zd 107 13 of of IN cord-015569-vy49r1zd 107 14 interactions interaction NNS cord-015569-vy49r1zd 107 15 that that WDT cord-015569-vy49r1zd 107 16 regulates regulate VBZ cord-015569-vy49r1zd 107 17 synapse synapse NN cord-015569-vy49r1zd 107 18 formation formation NN cord-015569-vy49r1zd 107 19 . . . cord-015569-vy49r1zd 108 1 In in IN cord-015569-vy49r1zd 108 2 this this DT cord-015569-vy49r1zd 108 3 study study NN cord-015569-vy49r1zd 108 4 , , , cord-015569-vy49r1zd 108 5 in in IN cord-015569-vy49r1zd 108 6 order order NN cord-015569-vy49r1zd 108 7 to to TO cord-015569-vy49r1zd 108 8 test test VB cord-015569-vy49r1zd 108 9 whether whether IN cord-015569-vy49r1zd 108 10 the the DT cord-015569-vy49r1zd 108 11 cadherins cadherin NNS cord-015569-vy49r1zd 108 12 are be VBP cord-015569-vy49r1zd 108 13 required require VBN cord-015569-vy49r1zd 108 14 for for IN cord-015569-vy49r1zd 108 15 formation formation NN cord-015569-vy49r1zd 108 16 of of IN cord-015569-vy49r1zd 108 17 synapse synapse NN cord-015569-vy49r1zd 108 18 between between IN cord-015569-vy49r1zd 108 19 gustatory gustatory JJ cord-015569-vy49r1zd 108 20 nerve nerve NN cord-015569-vy49r1zd 108 21 fibers fiber NNS cord-015569-vy49r1zd 108 22 and and CC cord-015569-vy49r1zd 108 23 taste taste VBP cord-015569-vy49r1zd 108 24 receptor receptor NN cord-015569-vy49r1zd 108 25 cells cell NNS cord-015569-vy49r1zd 108 26 , , , cord-015569-vy49r1zd 108 27 we -PRON- PRP cord-015569-vy49r1zd 108 28 have have VBP cord-015569-vy49r1zd 108 29 investigated investigate VBN cord-015569-vy49r1zd 108 30 expression expression NN cord-015569-vy49r1zd 108 31 patterns pattern NNS cord-015569-vy49r1zd 108 32 of of IN cord-015569-vy49r1zd 108 33 cadherin cadherin NN cord-015569-vy49r1zd 108 34 superfamily superfamily NN cord-015569-vy49r1zd 108 35 in in IN cord-015569-vy49r1zd 108 36 the the DT cord-015569-vy49r1zd 108 37 taste taste NN cord-015569-vy49r1zd 108 38 buds bud NNS cord-015569-vy49r1zd 108 39 . . . cord-015569-vy49r1zd 109 1 # # $ cord-015569-vy49r1zd 109 2 10 10 CD cord-015569-vy49r1zd 109 3 Induction Induction NNP cord-015569-vy49r1zd 109 4 of of IN cord-015569-vy49r1zd 109 5 Type Type NNP cord-015569-vy49r1zd 109 6 III III NNP cord-015569-vy49r1zd 109 7 - - HYPH cord-015569-vy49r1zd 109 8 like like JJ cord-015569-vy49r1zd 109 9 taste taste NN cord-015569-vy49r1zd 109 10 cells cell NNS cord-015569-vy49r1zd 109 11 in in IN cord-015569-vy49r1zd 109 12 threedimensional threedimensional JJ cord-015569-vy49r1zd 109 13 co co NN cord-015569-vy49r1zd 109 14 - - NN cord-015569-vy49r1zd 109 15 culture culture NN cord-015569-vy49r1zd 109 16 and and CC cord-015569-vy49r1zd 109 17 analysis analysis NN cord-015569-vy49r1zd 109 18 of of IN cord-015569-vy49r1zd 109 19 excitability excitability NN cord-015569-vy49r1zd 109 20 of of IN cord-015569-vy49r1zd 109 21 clonal clonal JJ cord-015569-vy49r1zd 109 22 cell cell NN cord-015569-vy49r1zd 109 23 lines line NNS cord-015569-vy49r1zd 109 24 derived derive VBN cord-015569-vy49r1zd 109 25 from from IN cord-015569-vy49r1zd 109 26 murine murine JJ cord-015569-vy49r1zd 109 27 taste taste NN cord-015569-vy49r1zd 109 28 buds bud NNS cord-015569-vy49r1zd 109 29 We -PRON- PRP cord-015569-vy49r1zd 109 30 have have VBP cord-015569-vy49r1zd 109 31 collected collect VBN cord-015569-vy49r1zd 109 32 taste taste NN cord-015569-vy49r1zd 109 33 buds bud NNS cord-015569-vy49r1zd 109 34 from from IN cord-015569-vy49r1zd 109 35 a a DT cord-015569-vy49r1zd 109 36 tongue tongue NN cord-015569-vy49r1zd 109 37 of of IN cord-015569-vy49r1zd 109 38 a a DT cord-015569-vy49r1zd 109 39 p53-deficient p53-deficient NN cord-015569-vy49r1zd 109 40 mouse mouse NN cord-015569-vy49r1zd 109 41 and and CC cord-015569-vy49r1zd 109 42 established establish VBN cord-015569-vy49r1zd 109 43 clonal clonal JJ cord-015569-vy49r1zd 109 44 cell cell NN cord-015569-vy49r1zd 109 45 lines line NNS cord-015569-vy49r1zd 109 46 ( ( -LRB- cord-015569-vy49r1zd 109 47 TBD TBD NNP cord-015569-vy49r1zd 109 48 cell cell NN cord-015569-vy49r1zd 109 49 lines line NNS cord-015569-vy49r1zd 109 50 ) ) -RRB- cord-015569-vy49r1zd 109 51 . . . cord-015569-vy49r1zd 110 1 Each each DT cord-015569-vy49r1zd 110 2 of of IN cord-015569-vy49r1zd 110 3 TBD TBD NNP cord-015569-vy49r1zd 110 4 cell cell NN cord-015569-vy49r1zd 110 5 lines line NNS cord-015569-vy49r1zd 110 6 expresses express VBZ cord-015569-vy49r1zd 110 7 gustducin gustducin NNP cord-015569-vy49r1zd 110 8 and and CC cord-015569-vy49r1zd 110 9 neural neural JJ cord-015569-vy49r1zd 110 10 cell cell NN cord-015569-vy49r1zd 110 11 adhesion adhesion NN cord-015569-vy49r1zd 110 12 molecule molecule NN cord-015569-vy49r1zd 110 13 ( ( -LRB- cord-015569-vy49r1zd 110 14 NCAM NCAM NNP cord-015569-vy49r1zd 110 15 ) ) -RRB- cord-015569-vy49r1zd 110 16 , , , cord-015569-vy49r1zd 110 17 suggesting suggest VBG cord-015569-vy49r1zd 110 18 that that IN cord-015569-vy49r1zd 110 19 TBD TBD NNP cord-015569-vy49r1zd 110 20 cell cell NN cord-015569-vy49r1zd 110 21 lines line NNS cord-015569-vy49r1zd 110 22 have have VBP cord-015569-vy49r1zd 110 23 characteristics characteristic NNS cord-015569-vy49r1zd 110 24 of of IN cord-015569-vy49r1zd 110 25 both both DT cord-015569-vy49r1zd 110 26 Type Type NNP cord-015569-vy49r1zd 110 27 II II NNP cord-015569-vy49r1zd 110 28 and and CC cord-015569-vy49r1zd 110 29 Type Type NNP cord-015569-vy49r1zd 110 30 III III NNP cord-015569-vy49r1zd 110 31 taste taste NN cord-015569-vy49r1zd 110 32 cells cell NNS cord-015569-vy49r1zd 110 33 . . . cord-015569-vy49r1zd 111 1 To to TO cord-015569-vy49r1zd 111 2 reveal reveal VB cord-015569-vy49r1zd 111 3 whether whether IN cord-015569-vy49r1zd 111 4 TBD TBD NNP cord-015569-vy49r1zd 111 5 cell cell NN cord-015569-vy49r1zd 111 6 lines line NNS cord-015569-vy49r1zd 111 7 have have VBP cord-015569-vy49r1zd 111 8 excitability excitability NN cord-015569-vy49r1zd 111 9 or or CC cord-015569-vy49r1zd 111 10 not not RB cord-015569-vy49r1zd 111 11 , , , cord-015569-vy49r1zd 111 12 we -PRON- PRP cord-015569-vy49r1zd 111 13 analyzed analyze VBD cord-015569-vy49r1zd 111 14 the the DT cord-015569-vy49r1zd 111 15 expression expression NN cord-015569-vy49r1zd 111 16 pattern pattern NN cord-015569-vy49r1zd 111 17 of of IN cord-015569-vy49r1zd 111 18 voltage voltage NN cord-015569-vy49r1zd 111 19 - - HYPH cord-015569-vy49r1zd 111 20 dependent dependent JJ cord-015569-vy49r1zd 111 21 sodium sodium NN cord-015569-vy49r1zd 111 22 channels channel NNS cord-015569-vy49r1zd 111 23 in in IN cord-015569-vy49r1zd 111 24 one one CD cord-015569-vy49r1zd 111 25 of of IN cord-015569-vy49r1zd 111 26 TBD TBD NNP cord-015569-vy49r1zd 111 27 cell cell NN cord-015569-vy49r1zd 111 28 lines line NNS cord-015569-vy49r1zd 111 29 , , , cord-015569-vy49r1zd 111 30 TBD TBD NNP cord-015569-vy49r1zd 111 31 - - HYPH cord-015569-vy49r1zd 111 32 a5 a5 NNP cord-015569-vy49r1zd 111 33 cells cell NNS cord-015569-vy49r1zd 111 34 and and CC cord-015569-vy49r1zd 111 35 performed perform VBD cord-015569-vy49r1zd 111 36 patch patch NN cord-015569-vy49r1zd 111 37 clamp clamp NN cord-015569-vy49r1zd 111 38 recording recording NN cord-015569-vy49r1zd 111 39 . . . cord-015569-vy49r1zd 112 1 SCN2A scn2a CD cord-015569-vy49r1zd 112 2 , , , cord-015569-vy49r1zd 112 3 SCN3A SCN3A NNP cord-015569-vy49r1zd 112 4 , , , cord-015569-vy49r1zd 112 5 SCN5A SCN5A NNP cord-015569-vy49r1zd 112 6 and and CC cord-015569-vy49r1zd 112 7 SCN9A SCN9A NNS cord-015569-vy49r1zd 112 8 genes gene NNS cord-015569-vy49r1zd 112 9 coding code VBG cord-015569-vy49r1zd 112 10 voltage voltage NN cord-015569-vy49r1zd 112 11 - - HYPH cord-015569-vy49r1zd 112 12 dependent dependent JJ cord-015569-vy49r1zd 112 13 sodium sodium NN cord-015569-vy49r1zd 112 14 channels channel NNS cord-015569-vy49r1zd 112 15 were be VBD cord-015569-vy49r1zd 112 16 detected detect VBN cord-015569-vy49r1zd 112 17 in in IN cord-015569-vy49r1zd 112 18 TBD TBD NNP cord-015569-vy49r1zd 112 19 - - HYPH cord-015569-vy49r1zd 112 20 a5 a5 NN cord-015569-vy49r1zd 112 21 cells cell NNS cord-015569-vy49r1zd 112 22 by by IN cord-015569-vy49r1zd 112 23 RT RT NNP cord-015569-vy49r1zd 112 24 - - HYPH cord-015569-vy49r1zd 112 25 PCR PCR NNP cord-015569-vy49r1zd 112 26 . . . cord-015569-vy49r1zd 113 1 Patch patch NN cord-015569-vy49r1zd 113 2 clamp clamp NN cord-015569-vy49r1zd 113 3 recording recording NN cord-015569-vy49r1zd 113 4 revealed reveal VBD cord-015569-vy49r1zd 113 5 that that IN cord-015569-vy49r1zd 113 6 TBD TBD NNP cord-015569-vy49r1zd 113 7 - - HYPH cord-015569-vy49r1zd 113 8 a5 a5 NN cord-015569-vy49r1zd 113 9 cells cell NNS cord-015569-vy49r1zd 113 10 had have VBD cord-015569-vy49r1zd 113 11 tonic tonic JJ cord-015569-vy49r1zd 113 12 outward outward JJ cord-015569-vy49r1zd 113 13 currents current NNS cord-015569-vy49r1zd 113 14 , , , cord-015569-vy49r1zd 113 15 but but CC cord-015569-vy49r1zd 113 16 lacked lack VBD cord-015569-vy49r1zd 113 17 transient transient JJ cord-015569-vy49r1zd 113 18 inward inward JJ cord-015569-vy49r1zd 113 19 currents current NNS cord-015569-vy49r1zd 113 20 . . . cord-015569-vy49r1zd 114 1 These these DT cord-015569-vy49r1zd 114 2 results result NNS cord-015569-vy49r1zd 114 3 suggest suggest VBP cord-015569-vy49r1zd 114 4 that that IN cord-015569-vy49r1zd 114 5 functional functional JJ cord-015569-vy49r1zd 114 6 voltage voltage NN cord-015569-vy49r1zd 114 7 - - HYPH cord-015569-vy49r1zd 114 8 dependent dependent JJ cord-015569-vy49r1zd 114 9 sodium sodium NN cord-015569-vy49r1zd 114 10 channels channel NNS cord-015569-vy49r1zd 114 11 are be VBP cord-015569-vy49r1zd 114 12 not not RB cord-015569-vy49r1zd 114 13 expressed express VBN cord-015569-vy49r1zd 114 14 in in IN cord-015569-vy49r1zd 114 15 TBD TBD NNP cord-015569-vy49r1zd 114 16 - - HYPH cord-015569-vy49r1zd 114 17 a5 a5 NN cord-015569-vy49r1zd 114 18 cells cell NNS cord-015569-vy49r1zd 114 19 . . . cord-015569-vy49r1zd 115 1 Next next RB cord-015569-vy49r1zd 115 2 , , , cord-015569-vy49r1zd 115 3 we -PRON- PRP cord-015569-vy49r1zd 115 4 tried try VBD cord-015569-vy49r1zd 115 5 to to TO cord-015569-vy49r1zd 115 6 establish establish VB cord-015569-vy49r1zd 115 7 a a DT cord-015569-vy49r1zd 115 8 culture culture NN cord-015569-vy49r1zd 115 9 model model NN cord-015569-vy49r1zd 115 10 mimicking mimic VBG cord-015569-vy49r1zd 115 11 the the DT cord-015569-vy49r1zd 115 12 lingual lingual JJ cord-015569-vy49r1zd 115 13 taste taste NN cord-015569-vy49r1zd 115 14 cells cell NNS cord-015569-vy49r1zd 115 15 of of IN cord-015569-vy49r1zd 115 16 the the DT cord-015569-vy49r1zd 115 17 mouse mouse NN cord-015569-vy49r1zd 115 18 . . . cord-015569-vy49r1zd 116 1 TBD TBD NNP cord-015569-vy49r1zd 116 2 cell cell NN cord-015569-vy49r1zd 116 3 lines line NNS cord-015569-vy49r1zd 116 4 were be VBD cord-015569-vy49r1zd 116 5 co co JJ cord-015569-vy49r1zd 116 6 - - JJ cord-015569-vy49r1zd 116 7 cultured cultured JJ cord-015569-vy49r1zd 116 8 with with IN cord-015569-vy49r1zd 116 9 a a DT cord-015569-vy49r1zd 116 10 lingual lingual JJ cord-015569-vy49r1zd 116 11 epithelial epithelial JJ cord-015569-vy49r1zd 116 12 cell cell NN cord-015569-vy49r1zd 116 13 line line NN cord-015569-vy49r1zd 116 14 ( ( -LRB- cord-015569-vy49r1zd 116 15 20A 20A NNP cord-015569-vy49r1zd 116 16 cell cell NN cord-015569-vy49r1zd 116 17 line line NN cord-015569-vy49r1zd 116 18 ) ) -RRB- cord-015569-vy49r1zd 116 19 and and CC cord-015569-vy49r1zd 116 20 a a DT cord-015569-vy49r1zd 116 21 lingual lingual JJ cord-015569-vy49r1zd 116 22 mesenchymederived mesenchymederived JJ cord-015569-vy49r1zd 116 23 cell cell NN cord-015569-vy49r1zd 116 24 line line NN cord-015569-vy49r1zd 116 25 ( ( -LRB- cord-015569-vy49r1zd 116 26 TMD TMD NNP cord-015569-vy49r1zd 116 27 cell cell NN cord-015569-vy49r1zd 116 28 line line NN cord-015569-vy49r1zd 116 29 ) ) -RRB- cord-015569-vy49r1zd 116 30 . . . cord-015569-vy49r1zd 117 1 TBD TBD NNP cord-015569-vy49r1zd 117 2 , , , cord-015569-vy49r1zd 117 3 20A 20A NNP cord-015569-vy49r1zd 117 4 and and CC cord-015569-vy49r1zd 117 5 TMD TMD NNP cord-015569-vy49r1zd 117 6 cell cell NN cord-015569-vy49r1zd 117 7 lines line NNS cord-015569-vy49r1zd 117 8 were be VBD cord-015569-vy49r1zd 117 9 maintained maintain VBN cord-015569-vy49r1zd 117 10 in in IN cord-015569-vy49r1zd 117 11 a a DT cord-015569-vy49r1zd 117 12 triple triple JJ cord-015569-vy49r1zd 117 13 co co NN cord-015569-vy49r1zd 117 14 - - NN cord-015569-vy49r1zd 117 15 culture culture NN cord-015569-vy49r1zd 117 16 , , , cord-015569-vy49r1zd 117 17 in in IN cord-015569-vy49r1zd 117 18 which which WDT cord-015569-vy49r1zd 117 19 TBD TBD NNP cord-015569-vy49r1zd 117 20 cells cell NNS cord-015569-vy49r1zd 117 21 were be VBD cord-015569-vy49r1zd 117 22 preseeded preseede VBN cord-015569-vy49r1zd 117 23 as as IN cord-015569-vy49r1zd 117 24 aggregates aggregate NNS cord-015569-vy49r1zd 117 25 or or CC cord-015569-vy49r1zd 117 26 in in IN cord-015569-vy49r1zd 117 27 suspension suspension NN cord-015569-vy49r1zd 117 28 on on IN cord-015569-vy49r1zd 117 29 the the DT cord-015569-vy49r1zd 117 30 collagen collagen NN cord-015569-vy49r1zd 117 31 gel gel NN cord-015569-vy49r1zd 117 32 containing contain VBG cord-015569-vy49r1zd 117 33 TMD TMD NNP cord-015569-vy49r1zd 117 34 cells cell NNS cord-015569-vy49r1zd 117 35 and and CC cord-015569-vy49r1zd 117 36 20A 20a NN cord-015569-vy49r1zd 117 37 cells cell NNS cord-015569-vy49r1zd 117 38 were be VBD cord-015569-vy49r1zd 117 39 laid lay VBN cord-015569-vy49r1zd 117 40 over over IN cord-015569-vy49r1zd 117 41 the the DT cord-015569-vy49r1zd 117 42 TBD TBD NNP cord-015569-vy49r1zd 117 43 cells cell NNS cord-015569-vy49r1zd 117 44 . . . cord-015569-vy49r1zd 118 1 TBD TBD NNP cord-015569-vy49r1zd 118 2 cells cell NNS cord-015569-vy49r1zd 118 3 in in IN cord-015569-vy49r1zd 118 4 the the DT cord-015569-vy49r1zd 118 5 triple triple JJ cord-015569-vy49r1zd 118 6 co co NN cord-015569-vy49r1zd 118 7 - - NN cord-015569-vy49r1zd 118 8 culture culture NN cord-015569-vy49r1zd 118 9 expressed express VBD cord-015569-vy49r1zd 118 10 NCAM NCAM NNP cord-015569-vy49r1zd 118 11 , , , cord-015569-vy49r1zd 118 12 however however RB cord-015569-vy49r1zd 118 13 gustducin gustducin NNP cord-015569-vy49r1zd 118 14 was be VBD cord-015569-vy49r1zd 118 15 not not RB cord-015569-vy49r1zd 118 16 immunohistochemically immunohistochemically RB cord-015569-vy49r1zd 118 17 detected detect VBN cord-015569-vy49r1zd 118 18 in in IN cord-015569-vy49r1zd 118 19 TBD TBD NNP cord-015569-vy49r1zd 118 20 cells cell NNS cord-015569-vy49r1zd 118 21 . . . cord-015569-vy49r1zd 119 1 This this DT cord-015569-vy49r1zd 119 2 result result NN cord-015569-vy49r1zd 119 3 suggests suggest VBZ cord-015569-vy49r1zd 119 4 that that IN cord-015569-vy49r1zd 119 5 TBD TBD NNP cord-015569-vy49r1zd 119 6 cells cell NNS cord-015569-vy49r1zd 119 7 in in IN cord-015569-vy49r1zd 119 8 the the DT cord-015569-vy49r1zd 119 9 co co NN cord-015569-vy49r1zd 119 10 - - NN cord-015569-vy49r1zd 119 11 culture culture NN cord-015569-vy49r1zd 119 12 exhibited exhibit VBD cord-015569-vy49r1zd 119 13 a a DT cord-015569-vy49r1zd 119 14 characteristic characteristic NN cord-015569-vy49r1zd 119 15 of of IN cord-015569-vy49r1zd 119 16 Type Type NNP cord-015569-vy49r1zd 119 17 III III NNP cord-015569-vy49r1zd 119 18 taste taste NN cord-015569-vy49r1zd 119 19 cells cell NNS cord-015569-vy49r1zd 119 20 . . . cord-015569-vy49r1zd 120 1 This this DT cord-015569-vy49r1zd 120 2 triple triple JJ cord-015569-vy49r1zd 120 3 co co JJ cord-015569-vy49r1zd 120 4 - - JJ cord-015569-vy49r1zd 120 5 culture culture JJ cord-015569-vy49r1zd 120 6 model model NN cord-015569-vy49r1zd 120 7 would would MD cord-015569-vy49r1zd 120 8 be be VB cord-015569-vy49r1zd 120 9 useful useful JJ cord-015569-vy49r1zd 120 10 to to TO cord-015569-vy49r1zd 120 11 study study VB cord-015569-vy49r1zd 120 12 morphogenesis morphogenesis NN cord-015569-vy49r1zd 120 13 and and CC cord-015569-vy49r1zd 120 14 functions function NNS cord-015569-vy49r1zd 120 15 of of IN cord-015569-vy49r1zd 120 16 the the DT cord-015569-vy49r1zd 120 17 gustatory gustatory JJ cord-015569-vy49r1zd 120 18 organ organ NN cord-015569-vy49r1zd 120 19 . . . cord-015569-vy49r1zd 121 1 Immunohistochemistry immunohistochemistry NN cord-015569-vy49r1zd 121 2 of of IN cord-015569-vy49r1zd 121 3 taste taste NN cord-015569-vy49r1zd 121 4 - - HYPH cord-015569-vy49r1zd 121 5 signaling signal VBG cord-015569-vy49r1zd 121 6 molecules molecule NNS cord-015569-vy49r1zd 121 7 is be VBZ cord-015569-vy49r1zd 121 8 useful useful JJ cord-015569-vy49r1zd 121 9 for for IN cord-015569-vy49r1zd 121 10 the the DT cord-015569-vy49r1zd 121 11 distinction distinction NN cord-015569-vy49r1zd 121 12 of of IN cord-015569-vy49r1zd 121 13 taste taste NN cord-015569-vy49r1zd 121 14 - - HYPH cord-015569-vy49r1zd 121 15 bud bud NN cord-015569-vy49r1zd 121 16 cell cell NN cord-015569-vy49r1zd 121 17 types type NNS cord-015569-vy49r1zd 121 18 . . . cord-015569-vy49r1zd 122 1 However however RB cord-015569-vy49r1zd 122 2 , , , cord-015569-vy49r1zd 122 3 the the DT cord-015569-vy49r1zd 122 4 optimal optimal JJ cord-015569-vy49r1zd 122 5 immunohistochemical immunohistochemical JJ cord-015569-vy49r1zd 122 6 detection detection NN cord-015569-vy49r1zd 122 7 depends depend VBZ cord-015569-vy49r1zd 122 8 on on IN cord-015569-vy49r1zd 122 9 specimen specimen NN cord-015569-vy49r1zd 122 10 - - HYPH cord-015569-vy49r1zd 122 11 preparing prepare VBG cord-015569-vy49r1zd 122 12 conditions condition NNS cord-015569-vy49r1zd 122 13 . . . cord-015569-vy49r1zd 123 1 Therefore therefore RB cord-015569-vy49r1zd 123 2 , , , cord-015569-vy49r1zd 123 3 this this DT cord-015569-vy49r1zd 123 4 study study NN cord-015569-vy49r1zd 123 5 aimed aim VBD cord-015569-vy49r1zd 123 6 to to TO cord-015569-vy49r1zd 123 7 examine examine VB cord-015569-vy49r1zd 123 8 differences difference NNS cord-015569-vy49r1zd 123 9 in in IN cord-015569-vy49r1zd 123 10 immunoreactivities immunoreactivitie NNS cord-015569-vy49r1zd 123 11 under under IN cord-015569-vy49r1zd 123 12 various various JJ cord-015569-vy49r1zd 123 13 tissue tissue NN cord-015569-vy49r1zd 123 14 - - HYPH cord-015569-vy49r1zd 123 15 preparing prepare VBG cord-015569-vy49r1zd 123 16 conditions condition NNS cord-015569-vy49r1zd 123 17 in in IN cord-015569-vy49r1zd 123 18 rat rat NN cord-015569-vy49r1zd 123 19 vallate vallate NN cord-015569-vy49r1zd 123 20 taste taste VBP cord-015569-vy49r1zd 123 21 buds bud NNS cord-015569-vy49r1zd 123 22 for for IN cord-015569-vy49r1zd 123 23 some some DT cord-015569-vy49r1zd 123 24 typical typical JJ cord-015569-vy49r1zd 123 25 markers marker NNS cord-015569-vy49r1zd 123 26 of of IN cord-015569-vy49r1zd 123 27 gustatory gustatory JJ cord-015569-vy49r1zd 123 28 cells cell NNS cord-015569-vy49r1zd 123 29 as as IN cord-015569-vy49r1zd 123 30 follows follow VBZ cord-015569-vy49r1zd 123 31 : : : cord-015569-vy49r1zd 123 32 gustducin gustducin NNP cord-015569-vy49r1zd 123 33 , , , cord-015569-vy49r1zd 123 34 type type NN cord-015569-vy49r1zd 123 35 III iii CD cord-015569-vy49r1zd 123 36 inositol inositol NN cord-015569-vy49r1zd 123 37 triphosphate triphosphate NN cord-015569-vy49r1zd 123 38 receptor receptor NN cord-015569-vy49r1zd 123 39 ( ( -LRB- cord-015569-vy49r1zd 123 40 IP IP NNP cord-015569-vy49r1zd 123 41 3 3 CD cord-015569-vy49r1zd 123 42 R3 R3 NNP cord-015569-vy49r1zd 123 43 ) ) -RRB- cord-015569-vy49r1zd 123 44 , , . cord-015569-vy49r1zd 124 1 synaptobrevin-2 synaptobrevin-2 NNP cord-015569-vy49r1zd 124 2 ( ( -LRB- cord-015569-vy49r1zd 124 3 VAMP2 VAMP2 NNP cord-015569-vy49r1zd 124 4 ) ) -RRB- cord-015569-vy49r1zd 124 5 , , , cord-015569-vy49r1zd 124 6 protein protein NN cord-015569-vy49r1zd 124 7 gene gene NN cord-015569-vy49r1zd 124 8 product product NN cord-015569-vy49r1zd 124 9 9.5 9.5 CD cord-015569-vy49r1zd 124 10 ( ( -LRB- cord-015569-vy49r1zd 124 11 PGP9.5 PGP9.5 NNP cord-015569-vy49r1zd 124 12 ) ) -RRB- cord-015569-vy49r1zd 124 13 , , , cord-015569-vy49r1zd 124 14 and and CC cord-015569-vy49r1zd 124 15 neural neural JJ cord-015569-vy49r1zd 124 16 cell cell NN cord-015569-vy49r1zd 124 17 adhesion adhesion NN cord-015569-vy49r1zd 124 18 molecule molecule NN cord-015569-vy49r1zd 124 19 ( ( -LRB- cord-015569-vy49r1zd 124 20 NCAM NCAM NNP cord-015569-vy49r1zd 124 21 ) ) -RRB- cord-015569-vy49r1zd 124 22 . . . cord-015569-vy49r1zd 125 1 Staining stain VBG cord-015569-vy49r1zd 125 2 patterns pattern NNS cord-015569-vy49r1zd 125 3 and and CC cord-015569-vy49r1zd 125 4 intensities intensity NNS cord-015569-vy49r1zd 125 5 of of IN cord-015569-vy49r1zd 125 6 immunoreactivities immunoreactivitie NNS cord-015569-vy49r1zd 125 7 for for IN cord-015569-vy49r1zd 125 8 these these DT cord-015569-vy49r1zd 125 9 molecules molecule NNS cord-015569-vy49r1zd 125 10 varied vary VBN cord-015569-vy49r1zd 125 11 according accord VBG cord-015569-vy49r1zd 125 12 to to IN cord-015569-vy49r1zd 125 13 tissue tissue NN cord-015569-vy49r1zd 125 14 - - HYPH cord-015569-vy49r1zd 125 15 preparing prepare VBG cord-015569-vy49r1zd 125 16 conditions condition NNS cord-015569-vy49r1zd 125 17 , , , cord-015569-vy49r1zd 125 18 especially especially RB cord-015569-vy49r1zd 125 19 the the DT cord-015569-vy49r1zd 125 20 fixation fixation NN cord-015569-vy49r1zd 125 21 . . . cord-015569-vy49r1zd 126 1 Confirming confirm VBG cord-015569-vy49r1zd 126 2 our -PRON- PRP$ cord-015569-vy49r1zd 126 3 previous previous JJ cord-015569-vy49r1zd 126 4 finding finding NN cord-015569-vy49r1zd 126 5 , , , cord-015569-vy49r1zd 126 6 gustducin gustducin NNP cord-015569-vy49r1zd 126 7 immunoreactivities immunoreactivities NNP cord-015569-vy49r1zd 126 8 were be VBD cord-015569-vy49r1zd 126 9 localized localize VBN cord-015569-vy49r1zd 126 10 to to IN cord-015569-vy49r1zd 126 11 the the DT cord-015569-vy49r1zd 126 12 upper upper JJ cord-015569-vy49r1zd 126 13 part part NN cord-015569-vy49r1zd 126 14 of of IN cord-015569-vy49r1zd 126 15 the the DT cord-015569-vy49r1zd 126 16 taste taste NN cord-015569-vy49r1zd 126 17 bud bud NN cord-015569-vy49r1zd 126 18 called call VBD cord-015569-vy49r1zd 126 19 taste taste NN cord-015569-vy49r1zd 126 20 hairs hair NNS cord-015569-vy49r1zd 126 21 in in IN cord-015569-vy49r1zd 126 22 case case NN cord-015569-vy49r1zd 126 23 of of IN cord-015569-vy49r1zd 126 24 short short JJ cord-015569-vy49r1zd 126 25 fixation fixation NN cord-015569-vy49r1zd 126 26 , , , cord-015569-vy49r1zd 126 27 but but CC cord-015569-vy49r1zd 126 28 to to IN cord-015569-vy49r1zd 126 29 the the DT cord-015569-vy49r1zd 126 30 cell cell NN cord-015569-vy49r1zd 126 31 body body NN cord-015569-vy49r1zd 126 32 cytoplasm cytoplasm NN cord-015569-vy49r1zd 126 33 excluding exclude VBG cord-015569-vy49r1zd 126 34 the the DT cord-015569-vy49r1zd 126 35 taste taste NN cord-015569-vy49r1zd 126 36 hairs hair NNS cord-015569-vy49r1zd 126 37 in in IN cord-015569-vy49r1zd 126 38 case case NN cord-015569-vy49r1zd 126 39 of of IN cord-015569-vy49r1zd 126 40 long long JJ cord-015569-vy49r1zd 126 41 fixation fixation NN cord-015569-vy49r1zd 126 42 . . . cord-015569-vy49r1zd 127 1 The the DT cord-015569-vy49r1zd 127 2 specific specific JJ cord-015569-vy49r1zd 127 3 immunostaining immunostaining NN cord-015569-vy49r1zd 127 4 for for IN cord-015569-vy49r1zd 127 5 IP IP NNP cord-015569-vy49r1zd 127 6 3 3 CD cord-015569-vy49r1zd 127 7 R3 R3 NNP cord-015569-vy49r1zd 127 8 was be VBD cord-015569-vy49r1zd 127 9 strong strong JJ cord-015569-vy49r1zd 127 10 in in IN cord-015569-vy49r1zd 127 11 short short JJ cord-015569-vy49r1zd 127 12 - - HYPH cord-015569-vy49r1zd 127 13 time time NN cord-015569-vy49r1zd 127 14 fixation fixation NN cord-015569-vy49r1zd 127 15 . . . cord-015569-vy49r1zd 128 1 On on IN cord-015569-vy49r1zd 128 2 the the DT cord-015569-vy49r1zd 128 3 other other JJ cord-015569-vy49r1zd 128 4 hand hand NN cord-015569-vy49r1zd 128 5 , , , cord-015569-vy49r1zd 128 6 those those DT cord-015569-vy49r1zd 128 7 for for IN cord-015569-vy49r1zd 128 8 VAMP2 vamp2 NN cord-015569-vy49r1zd 128 9 , , , cord-015569-vy49r1zd 128 10 PGP9.5 PGP9.5 NNP cord-015569-vy49r1zd 128 11 , , , cord-015569-vy49r1zd 128 12 and and CC cord-015569-vy49r1zd 128 13 NCAM NCAM NNP cord-015569-vy49r1zd 128 14 were be VBD cord-015569-vy49r1zd 128 15 intense intense JJ cord-015569-vy49r1zd 128 16 in in IN cord-015569-vy49r1zd 128 17 long long JJ cord-015569-vy49r1zd 128 18 - - HYPH cord-015569-vy49r1zd 128 19 time time NN cord-015569-vy49r1zd 128 20 fixation fixation NN cord-015569-vy49r1zd 128 21 . . . cord-015569-vy49r1zd 129 1 The the DT cord-015569-vy49r1zd 129 2 present present JJ cord-015569-vy49r1zd 129 3 data datum NNS cord-015569-vy49r1zd 129 4 suggest suggest VBP cord-015569-vy49r1zd 129 5 that that IN cord-015569-vy49r1zd 129 6 different different JJ cord-015569-vy49r1zd 129 7 experimental experimental JJ cord-015569-vy49r1zd 129 8 protocols protocol NNS cord-015569-vy49r1zd 129 9 cause cause VBP cord-015569-vy49r1zd 129 10 the the DT cord-015569-vy49r1zd 129 11 discrepancies discrepancy NNS cord-015569-vy49r1zd 129 12 in in IN cord-015569-vy49r1zd 129 13 immunoreactivities immunoreactivitie NNS cord-015569-vy49r1zd 129 14 for for IN cord-015569-vy49r1zd 129 15 these these DT cord-015569-vy49r1zd 129 16 markers marker NNS cord-015569-vy49r1zd 129 17 . . . cord-015569-vy49r1zd 130 1 Further further JJ cord-015569-vy49r1zd 130 2 investigations investigation NNS cord-015569-vy49r1zd 130 3 based base VBN cord-015569-vy49r1zd 130 4 on on IN cord-015569-vy49r1zd 130 5 this this DT cord-015569-vy49r1zd 130 6 study study NN cord-015569-vy49r1zd 130 7 should should MD cord-015569-vy49r1zd 130 8 provide provide VB cord-015569-vy49r1zd 130 9 important important JJ cord-015569-vy49r1zd 130 10 information information NN cord-015569-vy49r1zd 130 11 on on IN cord-015569-vy49r1zd 130 12 the the DT cord-015569-vy49r1zd 130 13 classification classification NN cord-015569-vy49r1zd 130 14 of of IN cord-015569-vy49r1zd 130 15 the the DT cord-015569-vy49r1zd 130 16 gustatory gustatory JJ cord-015569-vy49r1zd 130 17 cell cell NN cord-015569-vy49r1zd 130 18 type type NN cord-015569-vy49r1zd 130 19 . . . cord-015569-vy49r1zd 131 1 # # $ cord-015569-vy49r1zd 131 2 12 12 CD cord-015569-vy49r1zd 131 3 Immunohistochemical Immunohistochemical NNP cord-015569-vy49r1zd 131 4 localization localization NN cord-015569-vy49r1zd 131 5 of of IN cord-015569-vy49r1zd 131 6 NK1 NK1 NNP cord-015569-vy49r1zd 131 7 and and CC cord-015569-vy49r1zd 131 8 VPAC1 vpac1 NN cord-015569-vy49r1zd 131 9 receptors receptor NNS cord-015569-vy49r1zd 131 10 in in IN cord-015569-vy49r1zd 131 11 the the DT cord-015569-vy49r1zd 131 12 frog frog NN cord-015569-vy49r1zd 131 13 fungiform fungiform NN cord-015569-vy49r1zd 131 14 papilla papilla NN cord-015569-vy49r1zd 131 15 Hiroshi Hiroshi NNP cord-015569-vy49r1zd 131 16 Ando Ando NNP cord-015569-vy49r1zd 131 17 1 1 CD cord-015569-vy49r1zd 131 18 , , , cord-015569-vy49r1zd 131 19 Osamu Osamu NNP cord-015569-vy49r1zd 131 20 Tadokoro Tadokoro NNP cord-015569-vy49r1zd 131 21 2 2 CD cord-015569-vy49r1zd 131 22 , , , cord-015569-vy49r1zd 131 23 Naokazu Naokazu NNPS cord-015569-vy49r1zd 131 24 Asanuma Asanuma NNP cord-015569-vy49r1zd 131 25 1 1 CD cord-015569-vy49r1zd 131 26 , , , cord-015569-vy49r1zd 131 27 Mihoko Mihoko NNP cord-015569-vy49r1zd 131 28 Tomida Tomida NNP cord-015569-vy49r1zd 131 29 1 1 CD cord-015569-vy49r1zd 131 30 , , , cord-015569-vy49r1zd 131 31 Takami Takami NNP cord-015569-vy49r1zd 131 32 Nakamura Nakamura NNP cord-015569-vy49r1zd 131 33 1 1 CD cord-015569-vy49r1zd 131 34 and and CC cord-015569-vy49r1zd 131 35 Eiji Eiji NNP cord-015569-vy49r1zd 131 36 Kondo Kondo NNP cord-015569-vy49r1zd 131 37 2 2 CD cord-015569-vy49r1zd 131 38 1 1 CD cord-015569-vy49r1zd 131 39 Department Department NNP cord-015569-vy49r1zd 131 40 of of IN cord-015569-vy49r1zd 131 41 Oral Oral NNP cord-015569-vy49r1zd 131 42 Physiology Physiology NNP cord-015569-vy49r1zd 131 43 and and CC cord-015569-vy49r1zd 131 44 2 2 CD cord-015569-vy49r1zd 131 45 Department Department NNP cord-015569-vy49r1zd 131 46 of of IN cord-015569-vy49r1zd 131 47 Oral Oral NNP cord-015569-vy49r1zd 131 48 Anatomy Anatomy NNP cord-015569-vy49r1zd 131 49 , , , cord-015569-vy49r1zd 131 50 Matsumoto Matsumoto NNP cord-015569-vy49r1zd 131 51 Dental Dental NNP cord-015569-vy49r1zd 131 52 University University NNP cord-015569-vy49r1zd 131 53 , , , cord-015569-vy49r1zd 131 54 Shiojiri Shiojiri NNP cord-015569-vy49r1zd 131 55 399 399 CD cord-015569-vy49r1zd 131 56 - - HYPH cord-015569-vy49r1zd 131 57 0781 0781 CD cord-015569-vy49r1zd 131 58 , , , cord-015569-vy49r1zd 132 1 Japan Japan NNP cord-015569-vy49r1zd 133 1 Although although IN cord-015569-vy49r1zd 133 2 the the DT cord-015569-vy49r1zd 133 3 presence presence NN cord-015569-vy49r1zd 133 4 of of IN cord-015569-vy49r1zd 133 5 substance substance NN cord-015569-vy49r1zd 133 6 P p NN cord-015569-vy49r1zd 133 7 ( ( -LRB- cord-015569-vy49r1zd 133 8 SP SP NNP cord-015569-vy49r1zd 133 9 ) ) -RRB- cord-015569-vy49r1zd 133 10 immunoreactive immunoreactive JJ cord-015569-vy49r1zd 133 11 ( ( -LRB- cord-015569-vy49r1zd 133 12 IR IR NNP cord-015569-vy49r1zd 133 13 ) ) -RRB- cord-015569-vy49r1zd 133 14 nerve nerve NN cord-015569-vy49r1zd 133 15 fibers fiber NNS cord-015569-vy49r1zd 133 16 and and CC cord-015569-vy49r1zd 133 17 vasoactive vasoactive JJ cord-015569-vy49r1zd 133 18 intestinal intestinal JJ cord-015569-vy49r1zd 133 19 peptide peptide NN cord-015569-vy49r1zd 133 20 ( ( -LRB- cord-015569-vy49r1zd 133 21 VIP)-IR vip)-ir CD cord-015569-vy49r1zd 133 22 nerve nerve NN cord-015569-vy49r1zd 133 23 fibers fiber NNS cord-015569-vy49r1zd 133 24 has have VBZ cord-015569-vy49r1zd 133 25 been be VBN cord-015569-vy49r1zd 133 26 reported report VBN cord-015569-vy49r1zd 133 27 in in IN cord-015569-vy49r1zd 133 28 the the DT cord-015569-vy49r1zd 133 29 frog frog NN cord-015569-vy49r1zd 133 30 fungiform fungiform NN cord-015569-vy49r1zd 133 31 papilla papilla NNP cord-015569-vy49r1zd 133 32 , , , cord-015569-vy49r1zd 133 33 the the DT cord-015569-vy49r1zd 133 34 functional functional JJ cord-015569-vy49r1zd 133 35 roles role NNS cord-015569-vy49r1zd 133 36 of of IN cord-015569-vy49r1zd 133 37 these these DT cord-015569-vy49r1zd 133 38 fibers fiber NNS cord-015569-vy49r1zd 133 39 remain remain VBP cord-015569-vy49r1zd 133 40 to to TO cord-015569-vy49r1zd 133 41 be be VB cord-015569-vy49r1zd 133 42 elucidated elucidate VBN cord-015569-vy49r1zd 133 43 . . . cord-015569-vy49r1zd 134 1 To to TO cord-015569-vy49r1zd 134 2 clarify clarify VB cord-015569-vy49r1zd 134 3 whether whether IN cord-015569-vy49r1zd 134 4 these these DT cord-015569-vy49r1zd 134 5 SP SP NNP cord-015569-vy49r1zd 134 6 - - HYPH cord-015569-vy49r1zd 134 7 IR IR NNP cord-015569-vy49r1zd 134 8 and and CC cord-015569-vy49r1zd 134 9 VIP VIP NNP cord-015569-vy49r1zd 134 10 - - HYPH cord-015569-vy49r1zd 134 11 IR IR NNP cord-015569-vy49r1zd 134 12 fibers fiber NNS cord-015569-vy49r1zd 134 13 play play VBP cord-015569-vy49r1zd 134 14 any any DT cord-015569-vy49r1zd 134 15 efferent efferent JJ cord-015569-vy49r1zd 134 16 roles role NNS cord-015569-vy49r1zd 134 17 in in IN cord-015569-vy49r1zd 134 18 the the DT cord-015569-vy49r1zd 134 19 taste taste NN cord-015569-vy49r1zd 134 20 disc disc NN cord-015569-vy49r1zd 134 21 in in IN cord-015569-vy49r1zd 134 22 the the DT cord-015569-vy49r1zd 134 23 fungiform fungiform NN cord-015569-vy49r1zd 134 24 papilla papilla NN cord-015569-vy49r1zd 134 25 , , , cord-015569-vy49r1zd 134 26 we -PRON- PRP cord-015569-vy49r1zd 134 27 immunohistochemically immunohistochemically RB cord-015569-vy49r1zd 134 28 examined examine VBD cord-015569-vy49r1zd 134 29 the the DT cord-015569-vy49r1zd 134 30 existence existence NN cord-015569-vy49r1zd 134 31 of of IN cord-015569-vy49r1zd 134 32 neurokinin neurokinin NNP cord-015569-vy49r1zd 134 33 1 1 CD cord-015569-vy49r1zd 134 34 receptor receptor NN cord-015569-vy49r1zd 134 35 ( ( -LRB- cord-015569-vy49r1zd 134 36 NK1R NK1R NNP cord-015569-vy49r1zd 134 37 ) ) -RRB- cord-015569-vy49r1zd 134 38 , , , cord-015569-vy49r1zd 134 39 which which WDT cord-015569-vy49r1zd 134 40 is be VBZ cord-015569-vy49r1zd 134 41 also also RB cord-015569-vy49r1zd 134 42 a a DT cord-015569-vy49r1zd 134 43 SP SP NNP cord-015569-vy49r1zd 134 44 receptor receptor NN cord-015569-vy49r1zd 134 45 , , , cord-015569-vy49r1zd 134 46 and and CC cord-015569-vy49r1zd 134 47 VIP vip NN cord-015569-vy49r1zd 134 48 and and CC cord-015569-vy49r1zd 134 49 pituitary pituitary NN cord-015569-vy49r1zd 134 50 adenylate adenylate NN cord-015569-vy49r1zd 134 51 cyclase cyclase NN cord-015569-vy49r1zd 134 52 activating activate VBG cord-015569-vy49r1zd 134 53 hormone hormone NN cord-015569-vy49r1zd 134 54 1 1 CD cord-015569-vy49r1zd 134 55 receptor receptor NN cord-015569-vy49r1zd 134 56 ( ( -LRB- cord-015569-vy49r1zd 134 57 VPAC1R vpac1r NN cord-015569-vy49r1zd 134 58 ) ) -RRB- cord-015569-vy49r1zd 134 59 , , , cord-015569-vy49r1zd 134 60 which which WDT cord-015569-vy49r1zd 134 61 is be VBZ cord-015569-vy49r1zd 134 62 also also RB cord-015569-vy49r1zd 134 63 a a DT cord-015569-vy49r1zd 134 64 VIP vip NN cord-015569-vy49r1zd 134 65 receptor receptor NN cord-015569-vy49r1zd 134 66 , , , cord-015569-vy49r1zd 134 67 in in IN cord-015569-vy49r1zd 134 68 the the DT cord-015569-vy49r1zd 134 69 fungiform fungiform NN cord-015569-vy49r1zd 134 70 papilla papilla NN cord-015569-vy49r1zd 134 71 of of IN cord-015569-vy49r1zd 134 72 the the DT cord-015569-vy49r1zd 134 73 frog frog NN cord-015569-vy49r1zd 134 74 , , , cord-015569-vy49r1zd 134 75 Rana Rana NNP cord-015569-vy49r1zd 134 76 catesbeiana catesbeiana NNP cord-015569-vy49r1zd 134 77 . . . cord-015569-vy49r1zd 135 1 Many many JJ cord-015569-vy49r1zd 135 2 NK1R NK1R NNP cord-015569-vy49r1zd 135 3 - - HYPH cord-015569-vy49r1zd 135 4 IR IR NNP cord-015569-vy49r1zd 135 5 structures structure NNS cord-015569-vy49r1zd 135 6 were be VBD cord-015569-vy49r1zd 135 7 observed observe VBN cord-015569-vy49r1zd 135 8 in in IN cord-015569-vy49r1zd 135 9 the the DT cord-015569-vy49r1zd 135 10 taste taste NN cord-015569-vy49r1zd 135 11 disc disc NN cord-015569-vy49r1zd 135 12 . . . cord-015569-vy49r1zd 136 1 These these DT cord-015569-vy49r1zd 136 2 were be VBD cord-015569-vy49r1zd 136 3 conical conical JJ cord-015569-vy49r1zd 136 4 in in IN cord-015569-vy49r1zd 136 5 shape shape NN cord-015569-vy49r1zd 136 6 in in IN cord-015569-vy49r1zd 136 7 the the DT cord-015569-vy49r1zd 136 8 middle middle JJ cord-015569-vy49r1zd 136 9 layer layer NN cord-015569-vy49r1zd 136 10 of of IN cord-015569-vy49r1zd 136 11 the the DT cord-015569-vy49r1zd 136 12 taste taste NN cord-015569-vy49r1zd 136 13 disc disc NN cord-015569-vy49r1zd 136 14 and and CC cord-015569-vy49r1zd 136 15 had have VBD cord-015569-vy49r1zd 136 16 a a DT cord-015569-vy49r1zd 136 17 rod rod NN cord-015569-vy49r1zd 136 18 - - HYPH cord-015569-vy49r1zd 136 19 like like JJ cord-015569-vy49r1zd 136 20 thin thin JJ cord-015569-vy49r1zd 136 21 apical apical JJ cord-015569-vy49r1zd 136 22 process process NN cord-015569-vy49r1zd 136 23 toward toward IN cord-015569-vy49r1zd 136 24 the the DT cord-015569-vy49r1zd 136 25 upper upper JJ cord-015569-vy49r1zd 136 26 layer layer NN cord-015569-vy49r1zd 136 27 of of IN cord-015569-vy49r1zd 136 28 the the DT cord-015569-vy49r1zd 136 29 taste taste NN cord-015569-vy49r1zd 136 30 disc disc NN cord-015569-vy49r1zd 136 31 . . . cord-015569-vy49r1zd 137 1 Double double JJ cord-015569-vy49r1zd 137 2 - - HYPH cord-015569-vy49r1zd 137 3 labeling labeling NN cord-015569-vy49r1zd 137 4 immunohistochemistry immunohistochemistry NN cord-015569-vy49r1zd 137 5 showed show VBD cord-015569-vy49r1zd 137 6 that that IN cord-015569-vy49r1zd 137 7 only only RB cord-015569-vy49r1zd 137 8 a a DT cord-015569-vy49r1zd 137 9 few few JJ cord-015569-vy49r1zd 137 10 NK1R NK1R NNP cord-015569-vy49r1zd 137 11 - - HYPH cord-015569-vy49r1zd 137 12 IR IR NNP cord-015569-vy49r1zd 137 13 structures structure NNS cord-015569-vy49r1zd 137 14 were be VBD cord-015569-vy49r1zd 137 15 located locate VBN cord-015569-vy49r1zd 137 16 adjacent adjacent JJ cord-015569-vy49r1zd 137 17 to to IN cord-015569-vy49r1zd 137 18 the the DT cord-015569-vy49r1zd 137 19 SP SP NNP cord-015569-vy49r1zd 137 20 - - HYPH cord-015569-vy49r1zd 137 21 IR IR NNP cord-015569-vy49r1zd 137 22 nerve nerve NN cord-015569-vy49r1zd 137 23 fibers fiber NNS cord-015569-vy49r1zd 137 24 in in IN cord-015569-vy49r1zd 137 25 the the DT cord-015569-vy49r1zd 137 26 taste taste NN cord-015569-vy49r1zd 137 27 disc disc NN cord-015569-vy49r1zd 137 28 . . . cord-015569-vy49r1zd 138 1 VPAC1R VPAC1R NNP cord-015569-vy49r1zd 138 2 immunoreactivity immunoreactivity NN cord-015569-vy49r1zd 138 3 was be VBD cord-015569-vy49r1zd 138 4 observed observe VBN cord-015569-vy49r1zd 138 5 in in IN cord-015569-vy49r1zd 138 6 the the DT cord-015569-vy49r1zd 138 7 taste taste NN cord-015569-vy49r1zd 138 8 disc disc NN cord-015569-vy49r1zd 138 9 cells cell NNS cord-015569-vy49r1zd 138 10 and and CC cord-015569-vy49r1zd 138 11 the the DT cord-015569-vy49r1zd 138 12 glossopharyngeal glossopharyngeal JJ cord-015569-vy49r1zd 138 13 nerve nerve NN cord-015569-vy49r1zd 138 14 bundle bundle NN cord-015569-vy49r1zd 138 15 beneath beneath IN cord-015569-vy49r1zd 138 16 the the DT cord-015569-vy49r1zd 138 17 taste taste NN cord-015569-vy49r1zd 138 18 disc disc NN cord-015569-vy49r1zd 138 19 . . . cord-015569-vy49r1zd 139 1 VPAC1R vpac1r NN cord-015569-vy49r1zd 139 2 - - HYPH cord-015569-vy49r1zd 139 3 IR IR NNP cord-015569-vy49r1zd 139 4 cells cell NNS cord-015569-vy49r1zd 139 5 in in IN cord-015569-vy49r1zd 139 6 the the DT cord-015569-vy49r1zd 139 7 taste taste NN cord-015569-vy49r1zd 139 8 disc disc NN cord-015569-vy49r1zd 139 9 had have VBD cord-015569-vy49r1zd 139 10 either either CC cord-015569-vy49r1zd 139 11 a a DT cord-015569-vy49r1zd 139 12 thin thin JJ cord-015569-vy49r1zd 139 13 or or CC cord-015569-vy49r1zd 139 14 thick thick JJ cord-015569-vy49r1zd 139 15 apical apical JJ cord-015569-vy49r1zd 139 16 process process NN cord-015569-vy49r1zd 139 17 . . . cord-015569-vy49r1zd 140 1 VIP vip NN cord-015569-vy49r1zd 140 2 - - HYPH cord-015569-vy49r1zd 140 3 immunonegative immunonegative JJ cord-015569-vy49r1zd 140 4 nerves nerve NNS cord-015569-vy49r1zd 140 5 beneath beneath IN cord-015569-vy49r1zd 140 6 the the DT cord-015569-vy49r1zd 140 7 taste taste NN cord-015569-vy49r1zd 140 8 disc disc NN cord-015569-vy49r1zd 140 9 showed show VBD cord-015569-vy49r1zd 140 10 VPAC1R vpac1r NN cord-015569-vy49r1zd 140 11 - - HYPH cord-015569-vy49r1zd 140 12 IR IR NNP cord-015569-vy49r1zd 140 13 . . . cord-015569-vy49r1zd 141 1 VIP VIP NNP cord-015569-vy49r1zd 141 2 - - HYPH cord-015569-vy49r1zd 141 3 IR IR NNP cord-015569-vy49r1zd 141 4 neuronal neuronal JJ cord-015569-vy49r1zd 141 5 cell cell NN cord-015569-vy49r1zd 141 6 bodies body NNS cord-015569-vy49r1zd 141 7 colocalized colocalize VBD cord-015569-vy49r1zd 141 8 VAPC1R vapc1r NN cord-015569-vy49r1zd 141 9 in in IN cord-015569-vy49r1zd 141 10 the the DT cord-015569-vy49r1zd 141 11 grossopharyngeal grossopharyngeal NN cord-015569-vy49r1zd 141 12 nerve nerve NN cord-015569-vy49r1zd 141 13 bundle bundle NN cord-015569-vy49r1zd 141 14 within within IN cord-015569-vy49r1zd 141 15 the the DT cord-015569-vy49r1zd 141 16 tongue tongue NN cord-015569-vy49r1zd 141 17 . . . cord-015569-vy49r1zd 142 1 The the DT cord-015569-vy49r1zd 142 2 presence presence NN cord-015569-vy49r1zd 142 3 of of IN cord-015569-vy49r1zd 142 4 the the DT cord-015569-vy49r1zd 142 5 NK1R NK1R NNP cord-015569-vy49r1zd 142 6 and and CC cord-015569-vy49r1zd 142 7 VPAC1R vpac1r NN cord-015569-vy49r1zd 142 8 in in IN cord-015569-vy49r1zd 142 9 the the DT cord-015569-vy49r1zd 142 10 taste taste NN cord-015569-vy49r1zd 142 11 disc disc NN cord-015569-vy49r1zd 142 12 suggests suggest VBZ cord-015569-vy49r1zd 142 13 that that IN cord-015569-vy49r1zd 142 14 SP SP NNP cord-015569-vy49r1zd 142 15 - - HYPH cord-015569-vy49r1zd 142 16 IR IR NNP cord-015569-vy49r1zd 142 17 and and CC cord-015569-vy49r1zd 142 18 VIP VIP NNP cord-015569-vy49r1zd 142 19 - - HYPH cord-015569-vy49r1zd 142 20 IR IR NNP cord-015569-vy49r1zd 142 21 nerve nerve NN cord-015569-vy49r1zd 142 22 fibers fiber NNS cord-015569-vy49r1zd 142 23 play play VBP cord-015569-vy49r1zd 142 24 efferent efferent JJ cord-015569-vy49r1zd 142 25 roles role NNS cord-015569-vy49r1zd 142 26 in in IN cord-015569-vy49r1zd 142 27 the the DT cord-015569-vy49r1zd 142 28 taste taste NN cord-015569-vy49r1zd 142 29 disc disc NN cord-015569-vy49r1zd 142 30 in in IN cord-015569-vy49r1zd 142 31 the the DT cord-015569-vy49r1zd 142 32 frog frog NN cord-015569-vy49r1zd 142 33 fungiform fungiform NN cord-015569-vy49r1zd 142 34 papilla papilla NN cord-015569-vy49r1zd 142 35 . . . cord-015569-vy49r1zd 143 1 # # $ cord-015569-vy49r1zd 143 2 13 13 CD cord-015569-vy49r1zd 143 3 Cesium cesium NN cord-015569-vy49r1zd 143 4 - - HYPH cord-015569-vy49r1zd 143 5 permeable permeable JJ cord-015569-vy49r1zd 143 6 potassium potassium NN cord-015569-vy49r1zd 143 7 channel channel NN cord-015569-vy49r1zd 143 8 in in IN cord-015569-vy49r1zd 143 9 the the DT cord-015569-vy49r1zd 143 10 rod rod NN cord-015569-vy49r1zd 143 11 cells cell NNS cord-015569-vy49r1zd 143 12 of of IN cord-015569-vy49r1zd 143 13 frog frog NN cord-015569-vy49r1zd 143 14 taste taste VBP cord-015569-vy49r1zd 143 15 disc disc NN cord-015569-vy49r1zd 143 16 In in IN cord-015569-vy49r1zd 143 17 animal animal NN cord-015569-vy49r1zd 143 18 cells cell NNS cord-015569-vy49r1zd 144 1 , , , cord-015569-vy49r1zd 144 2 the the DT cord-015569-vy49r1zd 144 3 resting rest VBG cord-015569-vy49r1zd 144 4 membrane membrane NN cord-015569-vy49r1zd 144 5 potential potential NN cord-015569-vy49r1zd 144 6 is be VBZ cord-015569-vy49r1zd 144 7 maintained maintain VBN cord-015569-vy49r1zd 144 8 by by IN cord-015569-vy49r1zd 144 9 random random JJ cord-015569-vy49r1zd 144 10 open open RB cord-015569-vy49r1zd 144 11 - - HYPH cord-015569-vy49r1zd 144 12 shut shut NN cord-015569-vy49r1zd 144 13 gating gating NN cord-015569-vy49r1zd 144 14 of of IN cord-015569-vy49r1zd 144 15 a a DT cord-015569-vy49r1zd 144 16 leaky leaky JJ cord-015569-vy49r1zd 144 17 potassium potassium NN cord-015569-vy49r1zd 144 18 channel channel NN cord-015569-vy49r1zd 144 19 . . . cord-015569-vy49r1zd 145 1 Frog Frog NNP cord-015569-vy49r1zd 145 2 taste taste VBP cord-015569-vy49r1zd 145 3 disc disc NN cord-015569-vy49r1zd 145 4 cells cell NNS cord-015569-vy49r1zd 145 5 display display VBP cord-015569-vy49r1zd 145 6 the the DT cord-015569-vy49r1zd 145 7 resting rest VBG cord-015569-vy49r1zd 145 8 membrane membrane NN cord-015569-vy49r1zd 145 9 potential potential NN cord-015569-vy49r1zd 145 10 of of IN cord-015569-vy49r1zd 145 11 about about RB cord-015569-vy49r1zd 145 12 -50 -50 NN cord-015569-vy49r1zd 146 1 mV. mV. NNP cord-015569-vy49r1zd 147 1 The the DT cord-015569-vy49r1zd 147 2 magnitude magnitude NN cord-015569-vy49r1zd 147 3 is be VBZ cord-015569-vy49r1zd 147 4 not not RB cord-015569-vy49r1zd 147 5 consistent consistent JJ cord-015569-vy49r1zd 147 6 with with IN cord-015569-vy49r1zd 147 7 the the DT cord-015569-vy49r1zd 147 8 equilibrium equilibrium NN cord-015569-vy49r1zd 147 9 potential potential NN cord-015569-vy49r1zd 147 10 of of IN cord-015569-vy49r1zd 147 11 potassium potassium NN cord-015569-vy49r1zd 147 12 ( ( -LRB- cord-015569-vy49r1zd 147 13 -90 -90 NNP cord-015569-vy49r1zd 147 14 mV mV NNP cord-015569-vy49r1zd 147 15 ) ) -RRB- cord-015569-vy49r1zd 147 16 . . . cord-015569-vy49r1zd 148 1 When when WRB cord-015569-vy49r1zd 148 2 internal internal JJ cord-015569-vy49r1zd 148 3 potassium potassium NN cord-015569-vy49r1zd 148 4 was be VBD cord-015569-vy49r1zd 148 5 replaced replace VBN cord-015569-vy49r1zd 148 6 with with IN cord-015569-vy49r1zd 148 7 cesium cesium NN cord-015569-vy49r1zd 148 8 in in IN cord-015569-vy49r1zd 148 9 whole whole JJ cord-015569-vy49r1zd 148 10 - - HYPH cord-015569-vy49r1zd 148 11 cell cell NN cord-015569-vy49r1zd 148 12 configuration configuration NN cord-015569-vy49r1zd 148 13 , , , cord-015569-vy49r1zd 148 14 the the DT cord-015569-vy49r1zd 148 15 rod rod NN cord-015569-vy49r1zd 148 16 cells cell NNS cord-015569-vy49r1zd 148 17 in in IN cord-015569-vy49r1zd 148 18 frog frog NN cord-015569-vy49r1zd 148 19 taste taste NN cord-015569-vy49r1zd 148 20 disc disc NN cord-015569-vy49r1zd 148 21 increased increase VBD cord-015569-vy49r1zd 148 22 a a DT cord-015569-vy49r1zd 148 23 parabolic parabolic JJ cord-015569-vy49r1zd 148 24 outward outward JJ cord-015569-vy49r1zd 148 25 current current NN cord-015569-vy49r1zd 148 26 gradually gradually RB cord-015569-vy49r1zd 148 27 and and CC cord-015569-vy49r1zd 148 28 displayed display VBD cord-015569-vy49r1zd 148 29 the the DT cord-015569-vy49r1zd 148 30 resting rest VBG cord-015569-vy49r1zd 148 31 membrane membrane NN cord-015569-vy49r1zd 148 32 potential potential NN cord-015569-vy49r1zd 148 33 of of IN cord-015569-vy49r1zd 148 34 -49 -49 CD cord-015569-vy49r1zd 149 1 ± ± NNP cord-015569-vy49r1zd 149 2 2 2 CD cord-015569-vy49r1zd 149 3 mV mV NNP cord-015569-vy49r1zd 149 4 ( ( -LRB- cord-015569-vy49r1zd 149 5 n=23 n=23 NNP cord-015569-vy49r1zd 149 6 ) ) -RRB- cord-015569-vy49r1zd 149 7 . . . cord-015569-vy49r1zd 150 1 The the DT cord-015569-vy49r1zd 150 2 wing wing NN cord-015569-vy49r1zd 150 3 cells cell NNS cord-015569-vy49r1zd 150 4 did do VBD cord-015569-vy49r1zd 150 5 not not RB cord-015569-vy49r1zd 150 6 possess possess VB cord-015569-vy49r1zd 150 7 the the DT cord-015569-vy49r1zd 150 8 outward outward JJ cord-015569-vy49r1zd 150 9 current current NN cord-015569-vy49r1zd 150 10 and and CC cord-015569-vy49r1zd 150 11 displayed display VBD cord-015569-vy49r1zd 150 12 the the DT cord-015569-vy49r1zd 150 13 resting resting NN cord-015569-vy49r1zd 150 14 potential potential NN cord-015569-vy49r1zd 150 15 of of IN cord-015569-vy49r1zd 150 16 5 5 CD cord-015569-vy49r1zd 150 17 ± ± CD cord-015569-vy49r1zd 150 18 1 1 CD cord-015569-vy49r1zd 150 19 mV mV NNP cord-015569-vy49r1zd 150 20 ( ( -LRB- cord-015569-vy49r1zd 150 21 n=41 n=41 RB cord-015569-vy49r1zd 150 22 ) ) -RRB- cord-015569-vy49r1zd 150 23 in in IN cord-015569-vy49r1zd 150 24 the the DT cord-015569-vy49r1zd 150 25 condition condition NN cord-015569-vy49r1zd 150 26 of of IN cord-015569-vy49r1zd 150 27 internal internal JJ cord-015569-vy49r1zd 150 28 cesium cesium NN cord-015569-vy49r1zd 150 29 solution solution NN cord-015569-vy49r1zd 150 30 . . . cord-015569-vy49r1zd 151 1 The the DT cord-015569-vy49r1zd 151 2 replacement replacement NN cord-015569-vy49r1zd 151 3 of of IN cord-015569-vy49r1zd 151 4 external external JJ cord-015569-vy49r1zd 151 5 normal normal JJ cord-015569-vy49r1zd 151 6 saline saline NN cord-015569-vy49r1zd 151 7 solution solution NN cord-015569-vy49r1zd 151 8 with with IN cord-015569-vy49r1zd 151 9 cesium cesium NN cord-015569-vy49r1zd 151 10 saline saline NN cord-015569-vy49r1zd 151 11 solution solution NN cord-015569-vy49r1zd 151 12 turned turn VBD cord-015569-vy49r1zd 151 13 the the DT cord-015569-vy49r1zd 151 14 parabolic parabolic JJ cord-015569-vy49r1zd 151 15 outward outward JJ cord-015569-vy49r1zd 151 16 current current NN cord-015569-vy49r1zd 151 17 to to IN cord-015569-vy49r1zd 151 18 the the DT cord-015569-vy49r1zd 151 19 inward inward JJ cord-015569-vy49r1zd 151 20 current current NN cord-015569-vy49r1zd 151 21 . . . cord-015569-vy49r1zd 152 1 The the DT cord-015569-vy49r1zd 152 2 inward inward JJ cord-015569-vy49r1zd 152 3 current current NN cord-015569-vy49r1zd 152 4 reversed reverse VBD cord-015569-vy49r1zd 152 5 at at IN cord-015569-vy49r1zd 152 6 2 2 CD cord-015569-vy49r1zd 152 7 ± ± CD cord-015569-vy49r1zd 152 8 1 1 CD cord-015569-vy49r1zd 152 9 mV mV NNP cord-015569-vy49r1zd 152 10 ( ( -LRB- cord-015569-vy49r1zd 152 11 n=10 n=10 NNP cord-015569-vy49r1zd 152 12 ) ) -RRB- cord-015569-vy49r1zd 152 13 which which WDT cord-015569-vy49r1zd 152 14 is be VBZ cord-015569-vy49r1zd 152 15 close close JJ cord-015569-vy49r1zd 152 16 to to IN cord-015569-vy49r1zd 152 17 the the DT cord-015569-vy49r1zd 152 18 equilibrium equilibrium NN cord-015569-vy49r1zd 152 19 potential potential NN cord-015569-vy49r1zd 152 20 of of IN cord-015569-vy49r1zd 152 21 cesium cesium NN cord-015569-vy49r1zd 152 22 ( ( -LRB- cord-015569-vy49r1zd 152 23 4 4 CD cord-015569-vy49r1zd 152 24 mV mV NNP cord-015569-vy49r1zd 152 25 ) ) -RRB- cord-015569-vy49r1zd 152 26 . . . cord-015569-vy49r1zd 153 1 Several several JJ cord-015569-vy49r1zd 153 2 experiments experiment NNS cord-015569-vy49r1zd 153 3 on on IN cord-015569-vy49r1zd 153 4 cationic cationic JJ cord-015569-vy49r1zd 153 5 replacement replacement NN cord-015569-vy49r1zd 153 6 showed show VBD cord-015569-vy49r1zd 153 7 the the DT cord-015569-vy49r1zd 153 8 permeability permeability NN cord-015569-vy49r1zd 153 9 ratio ratio NN cord-015569-vy49r1zd 153 10 of of IN cord-015569-vy49r1zd 153 11 P p NN cord-015569-vy49r1zd 153 12 K k NN cord-015569-vy49r1zd 153 13 :P :P . cord-015569-vy49r1zd 154 1 Cs Cs NNP cord-015569-vy49r1zd 154 2 :P :P . cord-015569-vy49r1zd 155 1 Na Na NNP cord-015569-vy49r1zd 155 2 :P :p SYM cord-015569-vy49r1zd 155 3 NMDG NMDG NNP cord-015569-vy49r1zd 155 4 = = SYM cord-015569-vy49r1zd 155 5 1.67:1.00:0.29:0.15 1.67:1.00:0.29:0.15 CD cord-015569-vy49r1zd 155 6 . . . cord-015569-vy49r1zd 156 1 Carbenoxolone Carbenoxolone NNP cord-015569-vy49r1zd 156 2 ( ( -LRB- cord-015569-vy49r1zd 156 3 CBX CBX NNP cord-015569-vy49r1zd 156 4 , , , cord-015569-vy49r1zd 156 5 a a DT cord-015569-vy49r1zd 156 6 blocker blocker NN cord-015569-vy49r1zd 156 7 of of IN cord-015569-vy49r1zd 156 8 pannexin pannexin NNP cord-015569-vy49r1zd 156 9 ) ) -RRB- cord-015569-vy49r1zd 156 10 inhibited inhibit VBD cord-015569-vy49r1zd 156 11 the the DT cord-015569-vy49r1zd 156 12 parabolic parabolic JJ cord-015569-vy49r1zd 156 13 outward outward JJ cord-015569-vy49r1zd 156 14 current current NN cord-015569-vy49r1zd 156 15 moderately moderately RB cord-015569-vy49r1zd 157 1 ( ( -LRB- cord-015569-vy49r1zd 157 2 IC IC NNP cord-015569-vy49r1zd 157 3 50 50 CD cord-015569-vy49r1zd 157 4 , , , cord-015569-vy49r1zd 157 5 26 26 CD cord-015569-vy49r1zd 157 6 lM lm NN cord-015569-vy49r1zd 157 7 ) ) -RRB- cord-015569-vy49r1zd 157 8 . . . cord-015569-vy49r1zd 158 1 The the DT cord-015569-vy49r1zd 158 2 dialysis dialysis NN cord-015569-vy49r1zd 158 3 of of IN cord-015569-vy49r1zd 158 4 20 20 CD cord-015569-vy49r1zd 158 5 lM lm NN cord-015569-vy49r1zd 158 6 arachidonic arachidonic NN cord-015569-vy49r1zd 158 7 acid acid NN cord-015569-vy49r1zd 158 8 in in IN cord-015569-vy49r1zd 158 9 internal internal JJ cord-015569-vy49r1zd 158 10 cesium cesium NN cord-015569-vy49r1zd 158 11 solution solution NN cord-015569-vy49r1zd 158 12 changed change VBD cord-015569-vy49r1zd 158 13 the the DT cord-015569-vy49r1zd 158 14 parabolic parabolic JJ cord-015569-vy49r1zd 158 15 outward outward JJ cord-015569-vy49r1zd 158 16 current current NN cord-015569-vy49r1zd 158 17 to to IN cord-015569-vy49r1zd 158 18 the the DT cord-015569-vy49r1zd 158 19 exponential exponential JJ cord-015569-vy49r1zd 158 20 one one CD cord-015569-vy49r1zd 158 21 and and CC cord-015569-vy49r1zd 158 22 depolarized depolarize VBD cord-015569-vy49r1zd 158 23 the the DT cord-015569-vy49r1zd 158 24 membrane membrane NN cord-015569-vy49r1zd 158 25 potential potential NN cord-015569-vy49r1zd 158 26 by by IN cord-015569-vy49r1zd 158 27 15 15 CD cord-015569-vy49r1zd 158 28 mV. mv. NN cord-015569-vy49r1zd 159 1 The the DT cord-015569-vy49r1zd 159 2 results result NNS cord-015569-vy49r1zd 159 3 suggest suggest VBP cord-015569-vy49r1zd 159 4 that that IN cord-015569-vy49r1zd 159 5 the the DT cord-015569-vy49r1zd 159 6 outward outward JJ cord-015569-vy49r1zd 159 7 cesium cesium NN cord-015569-vy49r1zd 159 8 current current JJ cord-015569-vy49r1zd 159 9 in in IN cord-015569-vy49r1zd 159 10 the the DT cord-015569-vy49r1zd 159 11 frog frog NN cord-015569-vy49r1zd 159 12 rod rod NN cord-015569-vy49r1zd 159 13 cells cell NNS cord-015569-vy49r1zd 159 14 may may MD cord-015569-vy49r1zd 159 15 flow flow VB cord-015569-vy49r1zd 159 16 through through IN cord-015569-vy49r1zd 159 17 a a DT cord-015569-vy49r1zd 159 18 novel novel JJ cord-015569-vy49r1zd 159 19 channel channel NN cord-015569-vy49r1zd 159 20 different different JJ cord-015569-vy49r1zd 159 21 from from IN cord-015569-vy49r1zd 159 22 mammalian mammalian JJ cord-015569-vy49r1zd 159 23 cesium cesium NN cord-015569-vy49r1zd 159 24 - - HYPH cord-015569-vy49r1zd 159 25 permeable permeable JJ cord-015569-vy49r1zd 159 26 potassium potassium NN cord-015569-vy49r1zd 159 27 channel channel NN cord-015569-vy49r1zd 159 28 . . . cord-015569-vy49r1zd 160 1 Capsaicin capsaicin NN cord-015569-vy49r1zd 160 2 , , , cord-015569-vy49r1zd 160 3 which which WDT cord-015569-vy49r1zd 160 4 is be VBZ cord-015569-vy49r1zd 160 5 the the DT cord-015569-vy49r1zd 160 6 main main JJ cord-015569-vy49r1zd 160 7 component component NN cord-015569-vy49r1zd 160 8 of of IN cord-015569-vy49r1zd 160 9 chili chili NN cord-015569-vy49r1zd 160 10 pepper pepper NN cord-015569-vy49r1zd 160 11 and and CC cord-015569-vy49r1zd 160 12 has have VBZ cord-015569-vy49r1zd 160 13 many many JJ cord-015569-vy49r1zd 160 14 physiological physiological JJ cord-015569-vy49r1zd 160 15 functions function NNS cord-015569-vy49r1zd 160 16 such such JJ cord-015569-vy49r1zd 160 17 as as IN cord-015569-vy49r1zd 160 18 increasing increase VBG cord-015569-vy49r1zd 160 19 perspiration perspiration NN cord-015569-vy49r1zd 160 20 and and CC cord-015569-vy49r1zd 160 21 energy energy NN cord-015569-vy49r1zd 160 22 metabolism metabolism NN cord-015569-vy49r1zd 160 23 , , , cord-015569-vy49r1zd 160 24 has have VBZ cord-015569-vy49r1zd 160 25 negative negative JJ cord-015569-vy49r1zd 160 26 effect effect NN cord-015569-vy49r1zd 160 27 of of IN cord-015569-vy49r1zd 160 28 its -PRON- PRP$ cord-015569-vy49r1zd 160 29 strong strong JJ cord-015569-vy49r1zd 160 30 pungency pungency NN cord-015569-vy49r1zd 160 31 . . . cord-015569-vy49r1zd 161 1 Capsiate Capsiate NNP cord-015569-vy49r1zd 161 2 was be VBD cord-015569-vy49r1zd 161 3 identified identify VBN cord-015569-vy49r1zd 161 4 from from IN cord-015569-vy49r1zd 161 5 ÔCH-19 ÔCH-19 NNP cord-015569-vy49r1zd 161 6 SweetÕ sweetõ XX cord-015569-vy49r1zd 161 7 ( ( -LRB- cord-015569-vy49r1zd 161 8 Capsicum Capsicum NNP cord-015569-vy49r1zd 161 9 annuun annuun NN cord-015569-vy49r1zd 161 10 L. L. NNP cord-015569-vy49r1zd 161 11 ) ) -RRB- cord-015569-vy49r1zd 161 12 , , , cord-015569-vy49r1zd 161 13 a a DT cord-015569-vy49r1zd 161 14 non non JJ cord-015569-vy49r1zd 161 15 - - JJ cord-015569-vy49r1zd 161 16 pungent pungent JJ cord-015569-vy49r1zd 161 17 cultivar cultivar NN cord-015569-vy49r1zd 161 18 of of IN cord-015569-vy49r1zd 161 19 red red JJ cord-015569-vy49r1zd 161 20 pepper pepper NN cord-015569-vy49r1zd 161 21 . . . cord-015569-vy49r1zd 162 1 Like like IN cord-015569-vy49r1zd 162 2 capsaicin capsaicin NN cord-015569-vy49r1zd 162 3 , , , cord-015569-vy49r1zd 162 4 capsiate capsiate NNP cord-015569-vy49r1zd 162 5 is be VBZ cord-015569-vy49r1zd 162 6 thought think VBN cord-015569-vy49r1zd 162 7 to to TO cord-015569-vy49r1zd 162 8 enhance enhance VB cord-015569-vy49r1zd 162 9 energy energy NN cord-015569-vy49r1zd 162 10 metabolism metabolism NN cord-015569-vy49r1zd 162 11 by by IN cord-015569-vy49r1zd 162 12 activating activate VBG cord-015569-vy49r1zd 162 13 the the DT cord-015569-vy49r1zd 162 14 sympathetic sympathetic JJ cord-015569-vy49r1zd 162 15 nervous nervous JJ cord-015569-vy49r1zd 162 16 system system NN cord-015569-vy49r1zd 162 17 . . . cord-015569-vy49r1zd 163 1 Human human JJ cord-015569-vy49r1zd 163 2 sensory sensory JJ cord-015569-vy49r1zd 163 3 evaluation evaluation NN cord-015569-vy49r1zd 163 4 tests test NNS cord-015569-vy49r1zd 163 5 demonstrated demonstrate VBD cord-015569-vy49r1zd 163 6 that that IN cord-015569-vy49r1zd 163 7 capsiate capsiate NN cord-015569-vy49r1zd 163 8 and and CC cord-015569-vy49r1zd 163 9 that that IN cord-015569-vy49r1zd 163 10 analogs analog NNS cord-015569-vy49r1zd 163 11 ( ( -LRB- cord-015569-vy49r1zd 163 12 capsinoids capsinoids NNP cord-015569-vy49r1zd 163 13 ) ) -RRB- cord-015569-vy49r1zd 163 14 had have VBD cord-015569-vy49r1zd 163 15 very very RB cord-015569-vy49r1zd 163 16 weak weak JJ cord-015569-vy49r1zd 163 17 pungency pungency NN cord-015569-vy49r1zd 163 18 compared compare VBN cord-015569-vy49r1zd 163 19 with with IN cord-015569-vy49r1zd 163 20 capsaicin capsaicin NN cord-015569-vy49r1zd 163 21 and and CC cord-015569-vy49r1zd 163 22 capsaicin capsaicin NN cord-015569-vy49r1zd 163 23 analogs analog NNS cord-015569-vy49r1zd 163 24 ( ( -LRB- cord-015569-vy49r1zd 163 25 capsaicinoids capsaicinoids NNP cord-015569-vy49r1zd 163 26 ) ) -RRB- cord-015569-vy49r1zd 163 27 , , , cord-015569-vy49r1zd 163 28 and and CC cord-015569-vy49r1zd 163 29 the the DT cord-015569-vy49r1zd 163 30 difference difference NN cord-015569-vy49r1zd 163 31 of of IN cord-015569-vy49r1zd 163 32 threshold threshold NN cord-015569-vy49r1zd 163 33 level level NN cord-015569-vy49r1zd 163 34 between between IN cord-015569-vy49r1zd 163 35 capsinoids capsinoid NNS cord-015569-vy49r1zd 163 36 and and CC cord-015569-vy49r1zd 163 37 capsaicinoids capsaicinoids NNP cord-015569-vy49r1zd 163 38 was be VBD cord-015569-vy49r1zd 163 39 about about RB cord-015569-vy49r1zd 163 40 1000-fold 1000-fold CD cord-015569-vy49r1zd 163 41 . . . cord-015569-vy49r1zd 164 1 However however RB cord-015569-vy49r1zd 164 2 , , , cord-015569-vy49r1zd 164 3 the the DT cord-015569-vy49r1zd 164 4 in in IN cord-015569-vy49r1zd 164 5 vivo vivo NNP cord-015569-vy49r1zd 164 6 studies study NNS cord-015569-vy49r1zd 164 7 focused focus VBD cord-015569-vy49r1zd 164 8 on on IN cord-015569-vy49r1zd 164 9 the the DT cord-015569-vy49r1zd 164 10 reception reception NN cord-015569-vy49r1zd 164 11 of of IN cord-015569-vy49r1zd 164 12 them -PRON- PRP cord-015569-vy49r1zd 164 13 in in IN cord-015569-vy49r1zd 164 14 oral oral JJ cord-015569-vy49r1zd 164 15 cavity cavity NN cord-015569-vy49r1zd 164 16 are be VBP cord-015569-vy49r1zd 164 17 few few JJ cord-015569-vy49r1zd 164 18 because because IN cord-015569-vy49r1zd 164 19 the the DT cord-015569-vy49r1zd 164 20 reception reception NN cord-015569-vy49r1zd 164 21 mechanism mechanism NN cord-015569-vy49r1zd 164 22 of of IN cord-015569-vy49r1zd 164 23 hot hot JJ cord-015569-vy49r1zd 164 24 taste taste NN cord-015569-vy49r1zd 164 25 is be VBZ cord-015569-vy49r1zd 164 26 unclear unclear JJ cord-015569-vy49r1zd 164 27 , , , cord-015569-vy49r1zd 164 28 and and CC cord-015569-vy49r1zd 164 29 the the DT cord-015569-vy49r1zd 164 30 reason reason NN cord-015569-vy49r1zd 164 31 of of IN cord-015569-vy49r1zd 164 32 weak weak JJ cord-015569-vy49r1zd 164 33 pungency pungency NN cord-015569-vy49r1zd 164 34 of of IN cord-015569-vy49r1zd 164 35 capsinoids capsinoid NNS cord-015569-vy49r1zd 164 36 is be VBZ cord-015569-vy49r1zd 164 37 not not RB cord-015569-vy49r1zd 164 38 well well RB cord-015569-vy49r1zd 164 39 understood understand VBN cord-015569-vy49r1zd 164 40 . . . cord-015569-vy49r1zd 165 1 Therefore therefore RB cord-015569-vy49r1zd 165 2 , , , cord-015569-vy49r1zd 165 3 this this DT cord-015569-vy49r1zd 165 4 study study NN cord-015569-vy49r1zd 165 5 focuses focus VBZ cord-015569-vy49r1zd 165 6 on on IN cord-015569-vy49r1zd 165 7 the the DT cord-015569-vy49r1zd 165 8 reception reception NN cord-015569-vy49r1zd 165 9 of of IN cord-015569-vy49r1zd 165 10 capsinoids capsinoids NNP cord-015569-vy49r1zd 165 11 and and CC cord-015569-vy49r1zd 165 12 capsaicinoids capsaicinoids NNP cord-015569-vy49r1zd 165 13 in in IN cord-015569-vy49r1zd 165 14 the the DT cord-015569-vy49r1zd 165 15 oral oral JJ cord-015569-vy49r1zd 165 16 cavity cavity NN cord-015569-vy49r1zd 165 17 . . . cord-015569-vy49r1zd 166 1 Firstly firstly RB cord-015569-vy49r1zd 166 2 , , , cord-015569-vy49r1zd 166 3 we -PRON- PRP cord-015569-vy49r1zd 166 4 performed perform VBD cord-015569-vy49r1zd 166 5 two two CD cord-015569-vy49r1zd 166 6 - - HYPH cord-015569-vy49r1zd 166 7 bottle bottle NN cord-015569-vy49r1zd 166 8 preference preference NN cord-015569-vy49r1zd 166 9 tests test NNS cord-015569-vy49r1zd 166 10 using use VBG cord-015569-vy49r1zd 166 11 rats rat NNS cord-015569-vy49r1zd 166 12 and and CC cord-015569-vy49r1zd 166 13 confirmed confirm VBD cord-015569-vy49r1zd 166 14 that that IN cord-015569-vy49r1zd 166 15 they -PRON- PRP cord-015569-vy49r1zd 166 16 began begin VBD cord-015569-vy49r1zd 166 17 to to TO cord-015569-vy49r1zd 166 18 avoid avoid VB cord-015569-vy49r1zd 166 19 capsinoids capsinoid NNS cord-015569-vy49r1zd 166 20 at at IN cord-015569-vy49r1zd 166 21 about about IN cord-015569-vy49r1zd 166 22 1000 1000 CD cord-015569-vy49r1zd 166 23 times time NNS cord-015569-vy49r1zd 166 24 higher high JJR cord-015569-vy49r1zd 166 25 concentrations concentration NNS cord-015569-vy49r1zd 166 26 than than IN cord-015569-vy49r1zd 166 27 that that DT cord-015569-vy49r1zd 166 28 of of IN cord-015569-vy49r1zd 166 29 capsaicinoids capsaicinoid NNS cord-015569-vy49r1zd 166 30 . . . cord-015569-vy49r1zd 167 1 In in IN cord-015569-vy49r1zd 167 2 addition addition NN cord-015569-vy49r1zd 167 3 , , , cord-015569-vy49r1zd 167 4 we -PRON- PRP cord-015569-vy49r1zd 167 5 recorded record VBD cord-015569-vy49r1zd 167 6 the the DT cord-015569-vy49r1zd 167 7 lingual lingual JJ cord-015569-vy49r1zd 167 8 trigeminal trigeminal JJ cord-015569-vy49r1zd 167 9 nerve nerve NN cord-015569-vy49r1zd 167 10 responses response NNS cord-015569-vy49r1zd 167 11 to to IN cord-015569-vy49r1zd 167 12 capsinoids capsinoids NNP cord-015569-vy49r1zd 167 13 and and CC cord-015569-vy49r1zd 167 14 capsaicinoids capsaicinoids NNP cord-015569-vy49r1zd 167 15 and and CC cord-015569-vy49r1zd 167 16 found find VBD cord-015569-vy49r1zd 167 17 that that IN cord-015569-vy49r1zd 167 18 capsinoids capsinoid NNS cord-015569-vy49r1zd 167 19 induced induce VBD cord-015569-vy49r1zd 167 20 little little JJ cord-015569-vy49r1zd 167 21 responses response NNS cord-015569-vy49r1zd 167 22 while while IN cord-015569-vy49r1zd 167 23 capsaicinoids capsaicinoid NNS cord-015569-vy49r1zd 167 24 evoked evoke VBD cord-015569-vy49r1zd 167 25 apparent apparent JJ cord-015569-vy49r1zd 167 26 intensive intensive JJ cord-015569-vy49r1zd 167 27 responses response NNS cord-015569-vy49r1zd 167 28 . . . cord-015569-vy49r1zd 168 1 Such such JJ cord-015569-vy49r1zd 168 2 differences difference NNS cord-015569-vy49r1zd 168 3 were be VBD cord-015569-vy49r1zd 168 4 also also RB cord-015569-vy49r1zd 168 5 found find VBN cord-015569-vy49r1zd 168 6 in in IN cord-015569-vy49r1zd 168 7 immunohistochemical immunohistochemical JJ cord-015569-vy49r1zd 168 8 detection detection NN cord-015569-vy49r1zd 168 9 of of IN cord-015569-vy49r1zd 168 10 p p NN cord-015569-vy49r1zd 168 11 - - NN cord-015569-vy49r1zd 168 12 ERK ERK NNP cord-015569-vy49r1zd 168 13 in in IN cord-015569-vy49r1zd 168 14 the the DT cord-015569-vy49r1zd 168 15 trigeminal trigeminal JJ cord-015569-vy49r1zd 168 16 ganglion ganglion NN cord-015569-vy49r1zd 168 17 after after IN cord-015569-vy49r1zd 168 18 stimulation stimulation NN cord-015569-vy49r1zd 168 19 of of IN cord-015569-vy49r1zd 168 20 capsinoids capsinoid NNS cord-015569-vy49r1zd 168 21 and and CC cord-015569-vy49r1zd 168 22 capsaicinoids capsaicinoids NNP cord-015569-vy49r1zd 168 23 . . . cord-015569-vy49r1zd 169 1 Recent recent JJ cord-015569-vy49r1zd 169 2 studies study NNS cord-015569-vy49r1zd 169 3 using use VBG cord-015569-vy49r1zd 169 4 animal animal NN cord-015569-vy49r1zd 169 5 models model NNS cord-015569-vy49r1zd 169 6 of of IN cord-015569-vy49r1zd 169 7 binge binge NN cord-015569-vy49r1zd 169 8 eating eating NN cord-015569-vy49r1zd 169 9 shows show NNS cord-015569-vy49r1zd 169 10 that that IN cord-015569-vy49r1zd 169 11 the the DT cord-015569-vy49r1zd 169 12 accumbal accumbal JJ cord-015569-vy49r1zd 169 13 dopaminergic dopaminergic JJ cord-015569-vy49r1zd 169 14 neurotransmission neurotransmission NN cord-015569-vy49r1zd 169 15 is be VBZ cord-015569-vy49r1zd 169 16 elevated elevate VBN cord-015569-vy49r1zd 169 17 in in IN cord-015569-vy49r1zd 169 18 bingeing bingeing NN cord-015569-vy49r1zd 169 19 . . . cord-015569-vy49r1zd 170 1 It -PRON- PRP cord-015569-vy49r1zd 170 2 suggests suggest VBZ cord-015569-vy49r1zd 170 3 that that IN cord-015569-vy49r1zd 170 4 the the DT cord-015569-vy49r1zd 170 5 experience experience NN cord-015569-vy49r1zd 170 6 of of IN cord-015569-vy49r1zd 170 7 bingeing bingeing NN cord-015569-vy49r1zd 170 8 modifies modify VBZ cord-015569-vy49r1zd 170 9 the the DT cord-015569-vy49r1zd 170 10 activity activity NN cord-015569-vy49r1zd 170 11 of of IN cord-015569-vy49r1zd 170 12 midbrain midbrain NN cord-015569-vy49r1zd 170 13 dopaminergic dopaminergic JJ cord-015569-vy49r1zd 170 14 neurons neuron NNS cord-015569-vy49r1zd 170 15 in in IN cord-015569-vy49r1zd 170 16 the the DT cord-015569-vy49r1zd 170 17 ventral ventral JJ cord-015569-vy49r1zd 170 18 tegmental tegmental JJ cord-015569-vy49r1zd 170 19 area area NN cord-015569-vy49r1zd 170 20 ( ( -LRB- cord-015569-vy49r1zd 170 21 VTA VTA NNP cord-015569-vy49r1zd 170 22 ) ) -RRB- cord-015569-vy49r1zd 170 23 . . . cord-015569-vy49r1zd 171 1 However however RB cord-015569-vy49r1zd 171 2 , , , cord-015569-vy49r1zd 171 3 few few JJ cord-015569-vy49r1zd 171 4 evidences evidence NNS cord-015569-vy49r1zd 171 5 directly directly RB cord-015569-vy49r1zd 171 6 clarify clarify VBP cord-015569-vy49r1zd 171 7 whether whether IN cord-015569-vy49r1zd 171 8 the the DT cord-015569-vy49r1zd 171 9 activity activity NN cord-015569-vy49r1zd 171 10 of of IN cord-015569-vy49r1zd 171 11 the the DT cord-015569-vy49r1zd 171 12 VTA VTA NNP cord-015569-vy49r1zd 171 13 is be VBZ cord-015569-vy49r1zd 171 14 elevated elevate VBN cord-015569-vy49r1zd 171 15 anticipatorily anticipatorily NN cord-015569-vy49r1zd 171 16 , , , cord-015569-vy49r1zd 171 17 that that RB cord-015569-vy49r1zd 171 18 is is RB cord-015569-vy49r1zd 171 19 , , , cord-015569-vy49r1zd 171 20 before before IN cord-015569-vy49r1zd 171 21 receiving receive VBG cord-015569-vy49r1zd 171 22 the the DT cord-015569-vy49r1zd 171 23 oral oral JJ cord-015569-vy49r1zd 171 24 ( ( -LRB- cord-015569-vy49r1zd 171 25 taste taste NN cord-015569-vy49r1zd 171 26 ) ) -RRB- cord-015569-vy49r1zd 171 27 and/or and/or CC cord-015569-vy49r1zd 171 28 post post JJ cord-015569-vy49r1zd 171 29 - - JJ cord-015569-vy49r1zd 171 30 oral oral JJ cord-015569-vy49r1zd 171 31 ( ( -LRB- cord-015569-vy49r1zd 171 32 viscerosensory viscerosensory NN cord-015569-vy49r1zd 171 33 ) ) -RRB- cord-015569-vy49r1zd 171 34 cues cue NNS cord-015569-vy49r1zd 171 35 of of IN cord-015569-vy49r1zd 171 36 palatable palatable JJ cord-015569-vy49r1zd 171 37 food food NN cord-015569-vy49r1zd 171 38 . . . cord-015569-vy49r1zd 172 1 To to TO cord-015569-vy49r1zd 172 2 address address VB cord-015569-vy49r1zd 172 3 the the DT cord-015569-vy49r1zd 172 4 issue issue NN cord-015569-vy49r1zd 172 5 , , , cord-015569-vy49r1zd 172 6 we -PRON- PRP cord-015569-vy49r1zd 172 7 explored explore VBD cord-015569-vy49r1zd 172 8 possible possible JJ cord-015569-vy49r1zd 172 9 changes change NNS cord-015569-vy49r1zd 172 10 in in IN cord-015569-vy49r1zd 172 11 the the DT cord-015569-vy49r1zd 172 12 activity activity NN cord-015569-vy49r1zd 172 13 of of IN cord-015569-vy49r1zd 172 14 the the DT cord-015569-vy49r1zd 172 15 VTA VTA NNP cord-015569-vy49r1zd 172 16 neurons neuron NNS cord-015569-vy49r1zd 172 17 in in IN cord-015569-vy49r1zd 172 18 mice mouse NNS cord-015569-vy49r1zd 172 19 bingeing binge VBG cord-015569-vy49r1zd 172 20 on on IN cord-015569-vy49r1zd 172 21 sugar sugar NN cord-015569-vy49r1zd 172 22 by by IN cord-015569-vy49r1zd 172 23 immunohistochemical immunohistochemical JJ cord-015569-vy49r1zd 172 24 detection detection NN cord-015569-vy49r1zd 172 25 of of IN cord-015569-vy49r1zd 172 26 c c NNP cord-015569-vy49r1zd 172 27 - - HYPH cord-015569-vy49r1zd 172 28 fos fos NNP cord-015569-vy49r1zd 172 29 expression expression NN cord-015569-vy49r1zd 172 30 as as IN cord-015569-vy49r1zd 172 31 a a DT cord-015569-vy49r1zd 172 32 marker marker NN cord-015569-vy49r1zd 172 33 of of IN cord-015569-vy49r1zd 172 34 neuronal neuronal JJ cord-015569-vy49r1zd 172 35 activation activation NN cord-015569-vy49r1zd 172 36 . . . cord-015569-vy49r1zd 173 1 Under under IN cord-015569-vy49r1zd 173 2 food food NN cord-015569-vy49r1zd 173 3 restriction restriction NN cord-015569-vy49r1zd 173 4 , , , cord-015569-vy49r1zd 173 5 mice mouse NNS cord-015569-vy49r1zd 173 6 were be VBD cord-015569-vy49r1zd 173 7 subjected subject VBN cord-015569-vy49r1zd 173 8 to to IN cord-015569-vy49r1zd 173 9 a a DT cord-015569-vy49r1zd 173 10 binge binge NN cord-015569-vy49r1zd 173 11 - - HYPH cord-015569-vy49r1zd 173 12 type type NN cord-015569-vy49r1zd 173 13 eating eating NN cord-015569-vy49r1zd 173 14 training training NN cord-015569-vy49r1zd 173 15 for for IN cord-015569-vy49r1zd 173 16 10 10 CD cord-015569-vy49r1zd 173 17 days day NNS cord-015569-vy49r1zd 173 18 ( ( -LRB- cord-015569-vy49r1zd 173 19 day day NN cord-015569-vy49r1zd 173 20 1 1 CD cord-015569-vy49r1zd 173 21 - - SYM cord-015569-vy49r1zd 173 22 10 10 CD cord-015569-vy49r1zd 173 23 ) ) -RRB- cord-015569-vy49r1zd 173 24 , , , cord-015569-vy49r1zd 173 25 in in IN cord-015569-vy49r1zd 173 26 which which WDT cord-015569-vy49r1zd 173 27 their -PRON- PRP$ cord-015569-vy49r1zd 173 28 intake intake NN cord-015569-vy49r1zd 173 29 of of IN cord-015569-vy49r1zd 173 30 sucrose sucrose NN cord-015569-vy49r1zd 173 31 solution solution NN cord-015569-vy49r1zd 173 32 gradually gradually RB cord-015569-vy49r1zd 173 33 increased increase VBD cord-015569-vy49r1zd 173 34 day day NN cord-015569-vy49r1zd 173 35 by by IN cord-015569-vy49r1zd 173 36 day day NN cord-015569-vy49r1zd 173 37 , , , cord-015569-vy49r1zd 173 38 resulting result VBG cord-015569-vy49r1zd 173 39 in in IN cord-015569-vy49r1zd 173 40 its -PRON- PRP$ cord-015569-vy49r1zd 173 41 overconsumption overconsumption NN cord-015569-vy49r1zd 173 42 . . . cord-015569-vy49r1zd 174 1 On on IN cord-015569-vy49r1zd 174 2 day day NN cord-015569-vy49r1zd 174 3 11 11 CD cord-015569-vy49r1zd 174 4 , , , cord-015569-vy49r1zd 174 5 mice mouse NNS cord-015569-vy49r1zd 174 6 were be VBD cord-015569-vy49r1zd 174 7 deeply deeply RB cord-015569-vy49r1zd 174 8 anesthetized anesthetize VBN cord-015569-vy49r1zd 174 9 and and CC cord-015569-vy49r1zd 174 10 transcardially transcardially RB cord-015569-vy49r1zd 174 11 perfused perfuse VBN cord-015569-vy49r1zd 174 12 with with IN cord-015569-vy49r1zd 174 13 4 4 CD cord-015569-vy49r1zd 174 14 % % NN cord-015569-vy49r1zd 174 15 paraformaldehyde paraformaldehyde NNP cord-015569-vy49r1zd 174 16 before before IN cord-015569-vy49r1zd 174 17 receiving receive VBG cord-015569-vy49r1zd 174 18 the the DT cord-015569-vy49r1zd 174 19 sugar sugar NN cord-015569-vy49r1zd 174 20 exposure exposure NN cord-015569-vy49r1zd 174 21 . . . cord-015569-vy49r1zd 175 1 Brain brain NN cord-015569-vy49r1zd 175 2 sections section NNS cord-015569-vy49r1zd 175 3 including include VBG cord-015569-vy49r1zd 175 4 the the DT cord-015569-vy49r1zd 175 5 ventral ventral JJ cord-015569-vy49r1zd 175 6 midbrain midbrain NN cord-015569-vy49r1zd 175 7 were be VBD cord-015569-vy49r1zd 175 8 immunohistochemically immunohistochemically RB cord-015569-vy49r1zd 175 9 processed process VBN cord-015569-vy49r1zd 175 10 to to TO cord-015569-vy49r1zd 175 11 detect detect VB cord-015569-vy49r1zd 175 12 the the DT cord-015569-vy49r1zd 175 13 c c NNP cord-015569-vy49r1zd 175 14 - - HYPH cord-015569-vy49r1zd 175 15 fos fos NNP cord-015569-vy49r1zd 175 16 gene gene NN cord-015569-vy49r1zd 175 17 expression expression NN cord-015569-vy49r1zd 175 18 product product NN cord-015569-vy49r1zd 175 19 , , , cord-015569-vy49r1zd 175 20 Fos Fos NNP cord-015569-vy49r1zd 175 21 protein protein NN cord-015569-vy49r1zd 175 22 . . . cord-015569-vy49r1zd 176 1 The the DT cord-015569-vy49r1zd 176 2 number number NN cord-015569-vy49r1zd 176 3 of of IN cord-015569-vy49r1zd 176 4 Fos Fos NNP cord-015569-vy49r1zd 176 5 immunopositive immunopositive JJ cord-015569-vy49r1zd 176 6 neurons neuron NNS cord-015569-vy49r1zd 176 7 in in IN cord-015569-vy49r1zd 176 8 the the DT cord-015569-vy49r1zd 176 9 VTA VTA NNP cord-015569-vy49r1zd 176 10 of of IN cord-015569-vy49r1zd 176 11 trained train VBN cord-015569-vy49r1zd 176 12 mice mouse NNS cord-015569-vy49r1zd 176 13 was be VBD cord-015569-vy49r1zd 176 14 larger large JJR cord-015569-vy49r1zd 176 15 than than IN cord-015569-vy49r1zd 176 16 that that DT cord-015569-vy49r1zd 176 17 of of IN cord-015569-vy49r1zd 176 18 untrained untrained JJ cord-015569-vy49r1zd 176 19 naïve naïve JJ cord-015569-vy49r1zd 176 20 mice mouse NNS cord-015569-vy49r1zd 176 21 . . . cord-015569-vy49r1zd 177 1 The the DT cord-015569-vy49r1zd 177 2 finding finding NN cord-015569-vy49r1zd 177 3 suggests suggest VBZ cord-015569-vy49r1zd 177 4 that that IN cord-015569-vy49r1zd 177 5 the the DT cord-015569-vy49r1zd 177 6 activity activity NN cord-015569-vy49r1zd 177 7 of of IN cord-015569-vy49r1zd 177 8 the the DT cord-015569-vy49r1zd 177 9 VTA VTA NNP cord-015569-vy49r1zd 177 10 is be VBZ cord-015569-vy49r1zd 177 11 elevated elevate VBN cord-015569-vy49r1zd 177 12 anticipatorily anticipatorily NN cord-015569-vy49r1zd 177 13 before before IN cord-015569-vy49r1zd 177 14 sugar sugar NN cord-015569-vy49r1zd 177 15 exposure exposure NN cord-015569-vy49r1zd 177 16 and and CC cord-015569-vy49r1zd 177 17 contributes contribute VBZ cord-015569-vy49r1zd 177 18 to to IN cord-015569-vy49r1zd 177 19 the the DT cord-015569-vy49r1zd 177 20 stimulation stimulation NN cord-015569-vy49r1zd 177 21 of of IN cord-015569-vy49r1zd 177 22 the the DT cord-015569-vy49r1zd 177 23 mesolimbic mesolimbic JJ cord-015569-vy49r1zd 177 24 dopamine dopamine NN cord-015569-vy49r1zd 177 25 system system NN cord-015569-vy49r1zd 177 26 , , , cord-015569-vy49r1zd 177 27 resulting result VBG cord-015569-vy49r1zd 177 28 in in IN cord-015569-vy49r1zd 177 29 sugar sugar NN cord-015569-vy49r1zd 177 30 bingeing bingeing NN cord-015569-vy49r1zd 177 31 . . . cord-015569-vy49r1zd 178 1 # # $ cord-015569-vy49r1zd 178 2 16 16 CD cord-015569-vy49r1zd 178 3 Activation activation NN cord-015569-vy49r1zd 178 4 of of IN cord-015569-vy49r1zd 178 5 output output NN cord-015569-vy49r1zd 178 6 neurons neuron NNS cord-015569-vy49r1zd 178 7 in in IN cord-015569-vy49r1zd 178 8 the the DT cord-015569-vy49r1zd 178 9 basolateral basolateral JJ cord-015569-vy49r1zd 178 10 nucleus nucleus NN cord-015569-vy49r1zd 178 11 of of IN cord-015569-vy49r1zd 178 12 the the DT cord-015569-vy49r1zd 178 13 amygdala amygdala NN cord-015569-vy49r1zd 178 14 by by IN cord-015569-vy49r1zd 178 15 a a DT cord-015569-vy49r1zd 178 16 learned learn VBN cord-015569-vy49r1zd 178 17 aversive aversive JJ cord-015569-vy49r1zd 178 18 taste taste NN cord-015569-vy49r1zd 178 19 : : : cord-015569-vy49r1zd 178 20 a a DT cord-015569-vy49r1zd 178 21 manganese manganese NN cord-015569-vy49r1zd 178 22 - - HYPH cord-015569-vy49r1zd 178 23 enhanced enhance VBN cord-015569-vy49r1zd 178 24 MRI MRI NNP cord-015569-vy49r1zd 178 25 study study NN cord-015569-vy49r1zd 178 26 Tadashi Tadashi NNP cord-015569-vy49r1zd 178 27 Inui Inui NNP cord-015569-vy49r1zd 178 28 1 1 CD cord-015569-vy49r1zd 178 29 , , , cord-015569-vy49r1zd 178 30 Chizuko Chizuko NNP cord-015569-vy49r1zd 178 31 Inui Inui NNP cord-015569-vy49r1zd 178 32 - - HYPH cord-015569-vy49r1zd 178 33 Yamamoto Yamamoto NNP cord-015569-vy49r1zd 178 34 2 2 CD cord-015569-vy49r1zd 178 35 , , , cord-015569-vy49r1zd 178 36 Izumi Izumi NNP cord-015569-vy49r1zd 178 37 Ohzawa Ohzawa NNP cord-015569-vy49r1zd 178 38 3 3 CD cord-015569-vy49r1zd 178 39 , , , cord-015569-vy49r1zd 178 40 Yoshichika Yoshichika NNP cord-015569-vy49r1zd 178 41 Yoshioka Yoshioka NNP cord-015569-vy49r1zd 178 42 4 4 CD cord-015569-vy49r1zd 178 43 and and CC cord-015569-vy49r1zd 178 44 Tsuyoshi Tsuyoshi NNP cord-015569-vy49r1zd 178 45 Shimura Shimura NNP cord-015569-vy49r1zd 178 46 1 1 CD cord-015569-vy49r1zd 178 47 1 1 CD cord-015569-vy49r1zd 178 48 Grad Grad NNP cord-015569-vy49r1zd 178 49 . . . cord-015569-vy49r1zd 179 1 Sch Sch NNP cord-015569-vy49r1zd 179 2 . . . cord-015569-vy49r1zd 180 1 Human Human NNP cord-015569-vy49r1zd 180 2 Sci Sci NNP cord-015569-vy49r1zd 180 3 . . NNP cord-015569-vy49r1zd 180 4 , , , cord-015569-vy49r1zd 180 5 Osaka Osaka NNP cord-015569-vy49r1zd 180 6 Univ Univ NNP cord-015569-vy49r1zd 180 7 . . NNP cord-015569-vy49r1zd 180 8 , , , cord-015569-vy49r1zd 180 9 Suita Suita NNP cord-015569-vy49r1zd 180 10 , , , cord-015569-vy49r1zd 180 11 565 565 CD cord-015569-vy49r1zd 180 12 - - HYPH cord-015569-vy49r1zd 180 13 0871 0871 CD cord-015569-vy49r1zd 180 14 , , , cord-015569-vy49r1zd 180 15 Japan Japan NNP cord-015569-vy49r1zd 180 16 , , , cord-015569-vy49r1zd 180 17 2 2 CD cord-015569-vy49r1zd 180 18 Dept Dept NNP cord-015569-vy49r1zd 180 19 . . . cord-015569-vy49r1zd 181 1 Oral Oral NNP cord-015569-vy49r1zd 181 2 Anatomy Anatomy NNP cord-015569-vy49r1zd 181 3 , , , cord-015569-vy49r1zd 181 4 Osaka Osaka NNP cord-015569-vy49r1zd 181 5 Dental Dental NNP cord-015569-vy49r1zd 181 6 Univ Univ NNP cord-015569-vy49r1zd 181 7 . . NNP cord-015569-vy49r1zd 181 8 , , , cord-015569-vy49r1zd 181 9 Hirakata Hirakata NNP cord-015569-vy49r1zd 181 10 573 573 CD cord-015569-vy49r1zd 181 11 - - SYM cord-015569-vy49r1zd 181 12 1121 1121 CD cord-015569-vy49r1zd 181 13 , , , cord-015569-vy49r1zd 181 14 Japan Japan NNP cord-015569-vy49r1zd 181 15 , , , cord-015569-vy49r1zd 181 16 3 3 CD cord-015569-vy49r1zd 181 17 Grad Grad NNP cord-015569-vy49r1zd 181 18 . . . cord-015569-vy49r1zd 182 1 Sch Sch NNP cord-015569-vy49r1zd 182 2 . . . cord-015569-vy49r1zd 183 1 Frontier Frontier NNP cord-015569-vy49r1zd 183 2 Biosci Biosci NNP cord-015569-vy49r1zd 183 3 . . NNP cord-015569-vy49r1zd 183 4 , , , cord-015569-vy49r1zd 183 5 Osaka Osaka NNP cord-015569-vy49r1zd 183 6 Univ Univ NNP cord-015569-vy49r1zd 183 7 . . NNP cord-015569-vy49r1zd 183 8 , , , cord-015569-vy49r1zd 184 1 Suita Suita NNP cord-015569-vy49r1zd 184 2 565 565 CD cord-015569-vy49r1zd 184 3 - - HYPH cord-015569-vy49r1zd 184 4 0871 0871 CD cord-015569-vy49r1zd 184 5 , , , cord-015569-vy49r1zd 184 6 Japan Japan NNP cord-015569-vy49r1zd 184 7 and and CC cord-015569-vy49r1zd 184 8 4 4 CD cord-015569-vy49r1zd 184 9 Immunology Immunology NNP cord-015569-vy49r1zd 184 10 Frontier Frontier NNP cord-015569-vy49r1zd 184 11 Research Research NNP cord-015569-vy49r1zd 184 12 Center Center NNP cord-015569-vy49r1zd 184 13 , , , cord-015569-vy49r1zd 184 14 Osaka Osaka NNP cord-015569-vy49r1zd 184 15 University University NNP cord-015569-vy49r1zd 184 16 , , , cord-015569-vy49r1zd 184 17 Suita Suita NNP cord-015569-vy49r1zd 185 1 The the DT cord-015569-vy49r1zd 185 2 basolateral basolateral JJ cord-015569-vy49r1zd 185 3 nucleus nucleus NN cord-015569-vy49r1zd 185 4 of of IN cord-015569-vy49r1zd 185 5 the the DT cord-015569-vy49r1zd 185 6 amygdala amygdala NN cord-015569-vy49r1zd 185 7 ( ( -LRB- cord-015569-vy49r1zd 185 8 BLA BLA NNP cord-015569-vy49r1zd 185 9 ) ) -RRB- cord-015569-vy49r1zd 185 10 is be VBZ cord-015569-vy49r1zd 185 11 known know VBN cord-015569-vy49r1zd 185 12 to to TO cord-015569-vy49r1zd 185 13 play play VB cord-015569-vy49r1zd 185 14 an an DT cord-015569-vy49r1zd 185 15 important important JJ cord-015569-vy49r1zd 185 16 role role NN cord-015569-vy49r1zd 185 17 in in IN cord-015569-vy49r1zd 185 18 conditioned condition VBN cord-015569-vy49r1zd 185 19 taste taste NN cord-015569-vy49r1zd 185 20 aversion aversion NN cord-015569-vy49r1zd 185 21 ( ( -LRB- cord-015569-vy49r1zd 185 22 CTA CTA NNP cord-015569-vy49r1zd 185 23 ) ) -RRB- cord-015569-vy49r1zd 185 24 . . . cord-015569-vy49r1zd 186 1 Anatomical anatomical JJ cord-015569-vy49r1zd 186 2 studies study NNS cord-015569-vy49r1zd 186 3 have have VBP cord-015569-vy49r1zd 186 4 shown show VBN cord-015569-vy49r1zd 186 5 that that IN cord-015569-vy49r1zd 186 6 the the DT cord-015569-vy49r1zd 186 7 BLA BLA NNP cord-015569-vy49r1zd 186 8 has have VBZ cord-015569-vy49r1zd 186 9 reciprocal reciprocal JJ cord-015569-vy49r1zd 186 10 neural neural JJ cord-015569-vy49r1zd 186 11 projections projection NNS cord-015569-vy49r1zd 186 12 with with IN cord-015569-vy49r1zd 186 13 many many JJ cord-015569-vy49r1zd 186 14 brain brain NN cord-015569-vy49r1zd 186 15 regions region NNS cord-015569-vy49r1zd 186 16 . . . cord-015569-vy49r1zd 187 1 It -PRON- PRP cord-015569-vy49r1zd 187 2 is be VBZ cord-015569-vy49r1zd 187 3 still still RB cord-015569-vy49r1zd 187 4 unclear unclear JJ cord-015569-vy49r1zd 187 5 , , , cord-015569-vy49r1zd 187 6 however however RB cord-015569-vy49r1zd 187 7 , , , cord-015569-vy49r1zd 187 8 which which WDT cord-015569-vy49r1zd 187 9 connections connection NNS cord-015569-vy49r1zd 187 10 are be VBP cord-015569-vy49r1zd 187 11 involved involve VBN cord-015569-vy49r1zd 187 12 in in IN cord-015569-vy49r1zd 187 13 the the DT cord-015569-vy49r1zd 187 14 retrieval retrieval NN cord-015569-vy49r1zd 187 15 of of IN cord-015569-vy49r1zd 187 16 CTA CTA NNP cord-015569-vy49r1zd 187 17 . . . cord-015569-vy49r1zd 188 1 To to TO cord-015569-vy49r1zd 188 2 elucidate elucidate VB cord-015569-vy49r1zd 188 3 the the DT cord-015569-vy49r1zd 188 4 neural neural JJ cord-015569-vy49r1zd 188 5 circuits circuit NNS cord-015569-vy49r1zd 188 6 for for IN cord-015569-vy49r1zd 188 7 the the DT cord-015569-vy49r1zd 188 8 retrieval retrieval NN cord-015569-vy49r1zd 188 9 of of IN cord-015569-vy49r1zd 188 10 CTA CTA NNP cord-015569-vy49r1zd 188 11 , , , cord-015569-vy49r1zd 188 12 we -PRON- PRP cord-015569-vy49r1zd 188 13 examined examine VBD cord-015569-vy49r1zd 188 14 the the DT cord-015569-vy49r1zd 188 15 enhancement enhancement NN cord-015569-vy49r1zd 188 16 of of IN cord-015569-vy49r1zd 188 17 activity activity NN cord-015569-vy49r1zd 188 18 of of IN cord-015569-vy49r1zd 188 19 the the DT cord-015569-vy49r1zd 188 20 efferents efferent NNS cord-015569-vy49r1zd 188 21 from from IN cord-015569-vy49r1zd 188 22 the the DT cord-015569-vy49r1zd 188 23 BLA BLA NNP cord-015569-vy49r1zd 188 24 by by IN cord-015569-vy49r1zd 188 25 the the DT cord-015569-vy49r1zd 188 26 presentation presentation NN cord-015569-vy49r1zd 188 27 of of IN cord-015569-vy49r1zd 188 28 learned learn VBN cord-015569-vy49r1zd 188 29 aversive aversive JJ cord-015569-vy49r1zd 188 30 taste taste NN cord-015569-vy49r1zd 188 31 , , , cord-015569-vy49r1zd 188 32 using use VBG cord-015569-vy49r1zd 188 33 a a DT cord-015569-vy49r1zd 188 34 manganese manganese NN cord-015569-vy49r1zd 188 35 - - HYPH cord-015569-vy49r1zd 188 36 enhanced enhance VBN cord-015569-vy49r1zd 188 37 MRI mri NN cord-015569-vy49r1zd 188 38 technique technique NN cord-015569-vy49r1zd 188 39 . . . cord-015569-vy49r1zd 189 1 Rats rat NNS cord-015569-vy49r1zd 189 2 received receive VBD cord-015569-vy49r1zd 189 3 a a DT cord-015569-vy49r1zd 189 4 pairing pairing NN cord-015569-vy49r1zd 189 5 of of IN cord-015569-vy49r1zd 189 6 5 5 CD cord-015569-vy49r1zd 189 7 mM mm CD cord-015569-vy49r1zd 189 8 saccharin saccharin NN cord-015569-vy49r1zd 189 9 with with IN cord-015569-vy49r1zd 189 10 0.15 0.15 CD cord-015569-vy49r1zd 189 11 M M NNP cord-015569-vy49r1zd 189 12 lithium lithium NN cord-015569-vy49r1zd 189 13 chloride chloride NN cord-015569-vy49r1zd 189 14 or or CC cord-015569-vy49r1zd 189 15 saline saline NN cord-015569-vy49r1zd 189 16 ( ( -LRB- cord-015569-vy49r1zd 189 17 CTA CTA NNP cord-015569-vy49r1zd 189 18 or or CC cord-015569-vy49r1zd 189 19 sham sham NN cord-015569-vy49r1zd 189 20 group group NN cord-015569-vy49r1zd 189 21 , , , cord-015569-vy49r1zd 189 22 respectively respectively RB cord-015569-vy49r1zd 189 23 ) ) -RRB- cord-015569-vy49r1zd 189 24 . . . cord-015569-vy49r1zd 190 1 On on IN cord-015569-vy49r1zd 190 2 the the DT cord-015569-vy49r1zd 190 3 test test NN cord-015569-vy49r1zd 190 4 day day NN cord-015569-vy49r1zd 190 5 , , , cord-015569-vy49r1zd 190 6 thirty thirty CD cord-015569-vy49r1zd 190 7 min min NN cord-015569-vy49r1zd 190 8 after after IN cord-015569-vy49r1zd 190 9 an an DT cord-015569-vy49r1zd 190 10 injection injection NN cord-015569-vy49r1zd 190 11 of of IN cord-015569-vy49r1zd 190 12 40 40 CD cord-015569-vy49r1zd 190 13 mM mm CD cord-015569-vy49r1zd 190 14 MnCl MnCl NNP cord-015569-vy49r1zd 190 15 2 2 CD cord-015569-vy49r1zd 190 16 into into IN cord-015569-vy49r1zd 190 17 the the DT cord-015569-vy49r1zd 190 18 BLA BLA NNP cord-015569-vy49r1zd 190 19 , , , cord-015569-vy49r1zd 190 20 rats rat NNS cord-015569-vy49r1zd 190 21 were be VBD cord-015569-vy49r1zd 190 22 intraorally intraorally RB cord-015569-vy49r1zd 190 23 infused infuse VBN cord-015569-vy49r1zd 190 24 with with IN cord-015569-vy49r1zd 190 25 saccharin saccharin NN cord-015569-vy49r1zd 190 26 . . . cord-015569-vy49r1zd 191 1 Sixty Sixty NNP cord-015569-vy49r1zd 191 2 min min NN cord-015569-vy49r1zd 191 3 after after IN cord-015569-vy49r1zd 191 4 the the DT cord-015569-vy49r1zd 191 5 MnCl MnCl NNP cord-015569-vy49r1zd 191 6 2 2 CD cord-015569-vy49r1zd 191 7 injection injection NN cord-015569-vy49r1zd 191 8 , , , cord-015569-vy49r1zd 191 9 we -PRON- PRP cord-015569-vy49r1zd 191 10 acquired acquire VBD cord-015569-vy49r1zd 191 11 triple triple RB cord-015569-vy49r1zd 191 12 T1-weighed t1-weighed NN cord-015569-vy49r1zd 191 13 MR MR NNP cord-015569-vy49r1zd 191 14 images image NNS cord-015569-vy49r1zd 191 15 at at IN cord-015569-vy49r1zd 191 16 hourly hourly JJ cord-015569-vy49r1zd 191 17 intervals interval NNS cord-015569-vy49r1zd 191 18 . . . cord-015569-vy49r1zd 192 1 The the DT cord-015569-vy49r1zd 192 2 signal signal NN cord-015569-vy49r1zd 192 3 intensities intensity NNS cord-015569-vy49r1zd 192 4 of of IN cord-015569-vy49r1zd 192 5 MR MR NNP cord-015569-vy49r1zd 192 6 images image NNS cord-015569-vy49r1zd 192 7 , , , cord-015569-vy49r1zd 192 8 which which WDT cord-015569-vy49r1zd 192 9 reflect reflect VBP cord-015569-vy49r1zd 192 10 the the DT cord-015569-vy49r1zd 192 11 movements movement NNS cord-015569-vy49r1zd 192 12 of of IN cord-015569-vy49r1zd 192 13 manganese manganese NN cord-015569-vy49r1zd 192 14 by by IN cord-015569-vy49r1zd 192 15 the the DT cord-015569-vy49r1zd 192 16 activated activate VBN cord-015569-vy49r1zd 192 17 BLA BLA NNP cord-015569-vy49r1zd 192 18 neurons neuron NNS cord-015569-vy49r1zd 192 19 , , , cord-015569-vy49r1zd 192 20 were be VBD cord-015569-vy49r1zd 192 21 measured measure VBN cord-015569-vy49r1zd 192 22 . . . cord-015569-vy49r1zd 193 1 The the DT cord-015569-vy49r1zd 193 2 CTA CTA NNP cord-015569-vy49r1zd 193 3 group group NN cord-015569-vy49r1zd 193 4 showed show VBD cord-015569-vy49r1zd 193 5 significant significant JJ cord-015569-vy49r1zd 193 6 time time NN cord-015569-vy49r1zd 193 7 - - HYPH cord-015569-vy49r1zd 193 8 dependent dependent JJ cord-015569-vy49r1zd 193 9 increase increase NN cord-015569-vy49r1zd 193 10 of of IN cord-015569-vy49r1zd 193 11 signal signal JJ cord-015569-vy49r1zd 193 12 intensity intensity NN cord-015569-vy49r1zd 193 13 in in IN cord-015569-vy49r1zd 193 14 the the DT cord-015569-vy49r1zd 193 15 CeA CeA NNP cord-015569-vy49r1zd 193 16 than than IN cord-015569-vy49r1zd 193 17 did do VBD cord-015569-vy49r1zd 193 18 the the DT cord-015569-vy49r1zd 193 19 sham sham NN cord-015569-vy49r1zd 193 20 group group NN cord-015569-vy49r1zd 193 21 , , , cord-015569-vy49r1zd 193 22 indicating indicate VBG cord-015569-vy49r1zd 193 23 that that IN cord-015569-vy49r1zd 193 24 the the DT cord-015569-vy49r1zd 193 25 retrieval retrieval NN cord-015569-vy49r1zd 193 26 of of IN cord-015569-vy49r1zd 193 27 CTA CTA NNP cord-015569-vy49r1zd 193 28 activates activate VBZ cord-015569-vy49r1zd 193 29 efferents efferent NNS cord-015569-vy49r1zd 193 30 from from IN cord-015569-vy49r1zd 193 31 the the DT cord-015569-vy49r1zd 193 32 BLA BLA NNP cord-015569-vy49r1zd 193 33 to to IN cord-015569-vy49r1zd 193 34 the the DT cord-015569-vy49r1zd 193 35 CeA. CeA. NNP cord-015569-vy49r1zd 194 1 Furthermore furthermore RB cord-015569-vy49r1zd 194 2 , , , cord-015569-vy49r1zd 194 3 the the DT cord-015569-vy49r1zd 194 4 analyses analysis NNS cord-015569-vy49r1zd 194 5 based base VBN cord-015569-vy49r1zd 194 6 on on IN cord-015569-vy49r1zd 194 7 the the DT cord-015569-vy49r1zd 194 8 injection injection NN cord-015569-vy49r1zd 194 9 site site NN cord-015569-vy49r1zd 194 10 of of IN cord-015569-vy49r1zd 194 11 MnCl MnCl NNP cord-015569-vy49r1zd 194 12 2 2 CD cord-015569-vy49r1zd 194 13 ( ( -LRB- cord-015569-vy49r1zd 194 14 rostral rostral JJ cord-015569-vy49r1zd 194 15 or or CC cord-015569-vy49r1zd 194 16 caudal caudal JJ cord-015569-vy49r1zd 194 17 ) ) -RRB- cord-015569-vy49r1zd 194 18 demonstrated demonstrate VBD cord-015569-vy49r1zd 194 19 the the DT cord-015569-vy49r1zd 194 20 larger large JJR cord-015569-vy49r1zd 194 21 movements movement NNS cord-015569-vy49r1zd 194 22 of of IN cord-015569-vy49r1zd 194 23 manganese manganese NN cord-015569-vy49r1zd 194 24 toward toward IN cord-015569-vy49r1zd 194 25 the the DT cord-015569-vy49r1zd 194 26 CeA CeA NNP cord-015569-vy49r1zd 194 27 and and CC cord-015569-vy49r1zd 194 28 cortices cortex NNS cord-015569-vy49r1zd 194 29 ( ( -LRB- cord-015569-vy49r1zd 194 30 insular insular JJ cord-015569-vy49r1zd 194 31 and and CC cord-015569-vy49r1zd 194 32 piriform piriform NNP cord-015569-vy49r1zd 194 33 ) ) -RRB- cord-015569-vy49r1zd 194 34 in in IN cord-015569-vy49r1zd 194 35 the the DT cord-015569-vy49r1zd 194 36 rostrally rostrally RB cord-015569-vy49r1zd 194 37 - - HYPH cord-015569-vy49r1zd 194 38 injected inject VBN cord-015569-vy49r1zd 194 39 CTA CTA NNP cord-015569-vy49r1zd 194 40 group group NN cord-015569-vy49r1zd 194 41 . . . cord-015569-vy49r1zd 195 1 Therefore therefore RB cord-015569-vy49r1zd 195 2 , , , cord-015569-vy49r1zd 195 3 the the DT cord-015569-vy49r1zd 195 4 outputs output NNS cord-015569-vy49r1zd 195 5 of of IN cord-015569-vy49r1zd 195 6 efferent efferent JJ cord-015569-vy49r1zd 195 7 neurons neuron NNS cord-015569-vy49r1zd 195 8 in in IN cord-015569-vy49r1zd 195 9 the the DT cord-015569-vy49r1zd 195 10 rostral rostral JJ cord-015569-vy49r1zd 195 11 part part NN cord-015569-vy49r1zd 195 12 of of IN cord-015569-vy49r1zd 195 13 the the DT cord-015569-vy49r1zd 195 14 BLA BLA NNP cord-015569-vy49r1zd 195 15 may may MD cord-015569-vy49r1zd 195 16 be be VB cord-015569-vy49r1zd 195 17 separated separate VBN cord-015569-vy49r1zd 195 18 in in IN cord-015569-vy49r1zd 195 19 two two CD cord-015569-vy49r1zd 195 20 directions direction NNS cord-015569-vy49r1zd 195 21 , , , cord-015569-vy49r1zd 195 22 medial medial JJ cord-015569-vy49r1zd 195 23 ( ( -LRB- cord-015569-vy49r1zd 195 24 CeA cea JJ cord-015569-vy49r1zd 195 25 ) ) -RRB- cord-015569-vy49r1zd 195 26 and and CC cord-015569-vy49r1zd 195 27 lateral lateral JJ cord-015569-vy49r1zd 195 28 ( ( -LRB- cord-015569-vy49r1zd 195 29 cortices cortex NNS cord-015569-vy49r1zd 195 30 ) ) -RRB- cord-015569-vy49r1zd 195 31 . . . cord-015569-vy49r1zd 196 1 This this DT cord-015569-vy49r1zd 196 2 work work NN cord-015569-vy49r1zd 196 3 was be VBD cord-015569-vy49r1zd 196 4 supported support VBN cord-015569-vy49r1zd 196 5 by by IN cord-015569-vy49r1zd 196 6 KAKENHI KAKENHI NNP cord-015569-vy49r1zd 196 7 ( ( -LRB- cord-015569-vy49r1zd 196 8 22700748 22700748 CD cord-015569-vy49r1zd 196 9 ) ) -RRB- cord-015569-vy49r1zd 196 10 . . . cord-015569-vy49r1zd 197 1 The the DT cord-015569-vy49r1zd 197 2 13 13 CD cord-015569-vy49r1zd 197 3 C c NN cord-015569-vy49r1zd 197 4 isotope isotope NN cord-015569-vy49r1zd 197 5 - - HYPH cord-015569-vy49r1zd 197 6 labelled label VBN cord-015569-vy49r1zd 197 7 acetic acetic JJ cord-015569-vy49r1zd 197 8 acid acid NN cord-015569-vy49r1zd 197 9 breath breath NN cord-015569-vy49r1zd 197 10 test test NN cord-015569-vy49r1zd 197 11 is be VBZ cord-015569-vy49r1zd 197 12 a a DT cord-015569-vy49r1zd 197 13 common common JJ cord-015569-vy49r1zd 197 14 clinical clinical JJ cord-015569-vy49r1zd 197 15 method method NN cord-015569-vy49r1zd 197 16 to to TO cord-015569-vy49r1zd 197 17 evaluate evaluate VB cord-015569-vy49r1zd 197 18 gastric gastric JJ cord-015569-vy49r1zd 197 19 emptying emptying NN cord-015569-vy49r1zd 197 20 and and CC cord-015569-vy49r1zd 197 21 is be VBZ cord-015569-vy49r1zd 197 22 a a DT cord-015569-vy49r1zd 197 23 non non JJ cord-015569-vy49r1zd 197 24 - - JJ cord-015569-vy49r1zd 197 25 invasive invasive JJ cord-015569-vy49r1zd 197 26 and and CC cord-015569-vy49r1zd 197 27 repeatable repeatable JJ cord-015569-vy49r1zd 197 28 method method NN cord-015569-vy49r1zd 197 29 in in IN cord-015569-vy49r1zd 197 30 rodents rodent NNS cord-015569-vy49r1zd 197 31 . . . cord-015569-vy49r1zd 198 1 However however RB cord-015569-vy49r1zd 198 2 , , , cord-015569-vy49r1zd 198 3 the the DT cord-015569-vy49r1zd 198 4 sensitivity sensitivity NN cord-015569-vy49r1zd 198 5 of of IN cord-015569-vy49r1zd 198 6 this this DT cord-015569-vy49r1zd 198 7 test test NN cord-015569-vy49r1zd 198 8 to to TO cord-015569-vy49r1zd 198 9 detect detect VB cord-015569-vy49r1zd 198 10 changes change NNS cord-015569-vy49r1zd 198 11 in in IN cord-015569-vy49r1zd 198 12 gastric gastric JJ cord-015569-vy49r1zd 198 13 emptying emptying NN cord-015569-vy49r1zd 198 14 of of IN cord-015569-vy49r1zd 198 15 liquid liquid JJ cord-015569-vy49r1zd 198 16 diet diet NN cord-015569-vy49r1zd 198 17 in in IN cord-015569-vy49r1zd 198 18 mice mouse NNS cord-015569-vy49r1zd 198 19 has have VBZ cord-015569-vy49r1zd 198 20 not not RB cord-015569-vy49r1zd 198 21 been be VBN cord-015569-vy49r1zd 198 22 studied study VBN cord-015569-vy49r1zd 198 23 thoroughly thoroughly RB cord-015569-vy49r1zd 198 24 . . . cord-015569-vy49r1zd 199 1 The the DT cord-015569-vy49r1zd 199 2 present present JJ cord-015569-vy49r1zd 199 3 study study NN cord-015569-vy49r1zd 199 4 aimed aim VBN cord-015569-vy49r1zd 199 5 to to TO cord-015569-vy49r1zd 199 6 validate validate VB cord-015569-vy49r1zd 199 7 this this DT cord-015569-vy49r1zd 199 8 method method NN cord-015569-vy49r1zd 199 9 by by IN cord-015569-vy49r1zd 199 10 using use VBG cord-015569-vy49r1zd 199 11 Bethanechol Bethanechol NNP cord-015569-vy49r1zd 199 12 chloride chloride NN cord-015569-vy49r1zd 199 13 , , , cord-015569-vy49r1zd 199 14 atropine atropine NN cord-015569-vy49r1zd 199 15 sulfate sulfate NN cord-015569-vy49r1zd 199 16 , , , cord-015569-vy49r1zd 199 17 clonidine clonidine NN cord-015569-vy49r1zd 199 18 hydrochloride hydrochloride NN cord-015569-vy49r1zd 199 19 , , , cord-015569-vy49r1zd 199 20 CCK-8S CCK-8S NNP cord-015569-vy49r1zd 199 21 and and CC cord-015569-vy49r1zd 199 22 phenylthiocarbamide phenylthiocarbamide NN cord-015569-vy49r1zd 199 23 . . . cord-015569-vy49r1zd 200 1 Male male JJ cord-015569-vy49r1zd 200 2 C57BL-6J c57bl-6j NN cord-015569-vy49r1zd 200 3 mice mouse NNS cord-015569-vy49r1zd 200 4 after after IN cord-015569-vy49r1zd 200 5 overnight overnight JJ cord-015569-vy49r1zd 200 6 fasting fast VBG cord-015569-vy49r1zd 200 7 were be VBD cord-015569-vy49r1zd 200 8 placed place VBN cord-015569-vy49r1zd 200 9 in in IN cord-015569-vy49r1zd 200 10 the the DT cord-015569-vy49r1zd 200 11 metabolic metabolic JJ cord-015569-vy49r1zd 200 12 chamber chamber NN cord-015569-vy49r1zd 200 13 . . . cord-015569-vy49r1zd 201 1 Commercial commercial JJ cord-015569-vy49r1zd 201 2 liquid liquid NN cord-015569-vy49r1zd 201 3 diet diet NN cord-015569-vy49r1zd 201 4 containing contain VBG cord-015569-vy49r1zd 201 5 13 13 CD cord-015569-vy49r1zd 201 6 C c NN cord-015569-vy49r1zd 201 7 - - HYPH cord-015569-vy49r1zd 201 8 acetic acetic NN cord-015569-vy49r1zd 201 9 acid acid NN cord-015569-vy49r1zd 201 10 was be VBD cord-015569-vy49r1zd 201 11 used use VBN cord-015569-vy49r1zd 201 12 as as IN cord-015569-vy49r1zd 201 13 the the DT cord-015569-vy49r1zd 201 14 test test NN cord-015569-vy49r1zd 201 15 meal meal NN cord-015569-vy49r1zd 201 16 . . . cord-015569-vy49r1zd 202 1 After after IN cord-015569-vy49r1zd 202 2 intragastric intragastric JJ cord-015569-vy49r1zd 202 3 administration administration NN cord-015569-vy49r1zd 202 4 of of IN cord-015569-vy49r1zd 202 5 the the DT cord-015569-vy49r1zd 202 6 test test NN cord-015569-vy49r1zd 202 7 meal meal NN cord-015569-vy49r1zd 202 8 , , , cord-015569-vy49r1zd 202 9 the the DT cord-015569-vy49r1zd 202 10 expired expire VBN cord-015569-vy49r1zd 202 11 air air NN cord-015569-vy49r1zd 202 12 was be VBD cord-015569-vy49r1zd 202 13 collected collect VBN cord-015569-vy49r1zd 202 14 at at IN cord-015569-vy49r1zd 202 15 5-min 5-min JJ cord-015569-vy49r1zd 202 16 intervals interval NNS cord-015569-vy49r1zd 202 17 for for IN cord-015569-vy49r1zd 202 18 four four CD cord-015569-vy49r1zd 202 19 hours hour NNS cord-015569-vy49r1zd 202 20 by by IN cord-015569-vy49r1zd 202 21 a a DT cord-015569-vy49r1zd 202 22 fully fully RB cord-015569-vy49r1zd 202 23 automated automate VBN cord-015569-vy49r1zd 202 24 system system NN cord-015569-vy49r1zd 202 25 . . . cord-015569-vy49r1zd 203 1 The the DT cord-015569-vy49r1zd 203 2 13 13 CD cord-015569-vy49r1zd 203 3 CO co NN cord-015569-vy49r1zd 203 4 2 2 CD cord-015569-vy49r1zd 203 5 / / SYM cord-015569-vy49r1zd 203 6 12 12 CD cord-015569-vy49r1zd 203 7 CO co NN cord-015569-vy49r1zd 203 8 2 2 CD cord-015569-vy49r1zd 203 9 levels level NNS cord-015569-vy49r1zd 203 10 were be VBD cord-015569-vy49r1zd 203 11 measured measure VBN cord-015569-vy49r1zd 203 12 by by IN cord-015569-vy49r1zd 203 13 the the DT cord-015569-vy49r1zd 203 14 mass mass NN cord-015569-vy49r1zd 203 15 spectrometer spectrometer NN cord-015569-vy49r1zd 203 16 . . . cord-015569-vy49r1zd 204 1 The the DT cord-015569-vy49r1zd 204 2 13 13 CD cord-015569-vy49r1zd 204 3 CO co NN cord-015569-vy49r1zd 204 4 2 2 CD cord-015569-vy49r1zd 204 5 excretion excretion NN cord-015569-vy49r1zd 204 6 data datum NNS cord-015569-vy49r1zd 204 7 were be VBD cord-015569-vy49r1zd 204 8 analyzed analyze VBN cord-015569-vy49r1zd 204 9 for for IN cord-015569-vy49r1zd 204 10 calculation calculation NN cord-015569-vy49r1zd 204 11 of of IN cord-015569-vy49r1zd 204 12 gastric gastric JJ cord-015569-vy49r1zd 204 13 half half JJ cord-015569-vy49r1zd 204 14 excretion excretion NN cord-015569-vy49r1zd 204 15 time time NN cord-015569-vy49r1zd 204 16 ( ( -LRB- cord-015569-vy49r1zd 204 17 T T NNP cord-015569-vy49r1zd 204 18 1/2 1/2 CD cord-015569-vy49r1zd 204 19 ) ) -RRB- cord-015569-vy49r1zd 204 20 as as IN cord-015569-vy49r1zd 204 21 the the DT cord-015569-vy49r1zd 204 22 gastric gastric JJ cord-015569-vy49r1zd 204 23 emptying emptying NN cord-015569-vy49r1zd 204 24 parameter parameter NN cord-015569-vy49r1zd 204 25 . . . cord-015569-vy49r1zd 205 1 T t NN cord-015569-vy49r1zd 205 2 - - HYPH cord-015569-vy49r1zd 205 3 test test NN cord-015569-vy49r1zd 205 4 was be VBD cord-015569-vy49r1zd 205 5 used use VBN cord-015569-vy49r1zd 205 6 for for IN cord-015569-vy49r1zd 205 7 statistical statistical JJ cord-015569-vy49r1zd 205 8 analysis analysis NN cord-015569-vy49r1zd 205 9 ( ( -LRB- cord-015569-vy49r1zd 205 10 p<0.05 p<0.05 CD cord-015569-vy49r1zd 205 11 ) ) -RRB- cord-015569-vy49r1zd 205 12 . . . cord-015569-vy49r1zd 206 1 Bethanechol Bethanechol NNP cord-015569-vy49r1zd 206 2 chloride chloride NN cord-015569-vy49r1zd 206 3 decreased decrease VBD cord-015569-vy49r1zd 206 4 T T NNP cord-015569-vy49r1zd 206 5 1/2 1/2 CD cord-015569-vy49r1zd 206 6 of of IN cord-015569-vy49r1zd 206 7 liquid liquid JJ cord-015569-vy49r1zd 206 8 diet diet NN cord-015569-vy49r1zd 206 9 and and CC cord-015569-vy49r1zd 206 10 atropine atropine NN cord-015569-vy49r1zd 206 11 sulfate sulfate NN cord-015569-vy49r1zd 206 12 and and CC cord-015569-vy49r1zd 206 13 clonidine clonidine NN cord-015569-vy49r1zd 206 14 hydrochloride hydrochloride NN cord-015569-vy49r1zd 206 15 increased increase VBD cord-015569-vy49r1zd 206 16 T T NNP cord-015569-vy49r1zd 206 17 1/2 1/2 CD cord-015569-vy49r1zd 206 18 . . . cord-015569-vy49r1zd 207 1 CCK-8S CCK-8S NNP cord-015569-vy49r1zd 207 2 increased increase VBD cord-015569-vy49r1zd 207 3 T T NNP cord-015569-vy49r1zd 207 4 1/2 1/2 CD cord-015569-vy49r1zd 207 5 and and CC cord-015569-vy49r1zd 207 6 CCK1 CCK1 NNP cord-015569-vy49r1zd 207 7 receptor receptor NN cord-015569-vy49r1zd 207 8 antagonist antagonist NN cord-015569-vy49r1zd 207 9 , , , cord-015569-vy49r1zd 207 10 Devazepide Devazepide NNP cord-015569-vy49r1zd 207 11 , , , cord-015569-vy49r1zd 207 12 attenuated attenuate VBD cord-015569-vy49r1zd 207 13 the the DT cord-015569-vy49r1zd 207 14 delay delay NN cord-015569-vy49r1zd 207 15 of of IN cord-015569-vy49r1zd 207 16 gastric gastric JJ cord-015569-vy49r1zd 207 17 emptying emptying NN cord-015569-vy49r1zd 207 18 by by IN cord-015569-vy49r1zd 207 19 CCK-8S. CCK-8S. NNS cord-015569-vy49r1zd 207 20 Bitter bitter JJ cord-015569-vy49r1zd 207 21 tastant tastant NN cord-015569-vy49r1zd 207 22 , , , cord-015569-vy49r1zd 207 23 phenylthiocarbamide phenylthiocarbamide NN cord-015569-vy49r1zd 207 24 increased increase VBD cord-015569-vy49r1zd 207 25 T T NNP cord-015569-vy49r1zd 207 26 1/2 1/2 CD cord-015569-vy49r1zd 207 27 . . . cord-015569-vy49r1zd 208 1 Our -PRON- PRP$ cord-015569-vy49r1zd 208 2 study study NN cord-015569-vy49r1zd 208 3 indicated indicate VBD cord-015569-vy49r1zd 208 4 that that IN cord-015569-vy49r1zd 208 5 the the DT cord-015569-vy49r1zd 208 6 13 13 CD cord-015569-vy49r1zd 208 7 C c NN cord-015569-vy49r1zd 208 8 - - HYPH cord-015569-vy49r1zd 208 9 breath breath NN cord-015569-vy49r1zd 208 10 test test NN cord-015569-vy49r1zd 208 11 was be VBD cord-015569-vy49r1zd 208 12 sensitive sensitive JJ cord-015569-vy49r1zd 208 13 to to TO cord-015569-vy49r1zd 208 14 detect detect VB cord-015569-vy49r1zd 208 15 difference difference NN cord-015569-vy49r1zd 208 16 in in IN cord-015569-vy49r1zd 208 17 gastric gastric JJ cord-015569-vy49r1zd 208 18 emptying emptying NN cord-015569-vy49r1zd 208 19 of of IN cord-015569-vy49r1zd 208 20 liquid liquid JJ cord-015569-vy49r1zd 208 21 diet diet NN cord-015569-vy49r1zd 208 22 induced induce VBN cord-015569-vy49r1zd 208 23 by by IN cord-015569-vy49r1zd 208 24 pharmacological pharmacological JJ cord-015569-vy49r1zd 208 25 agents agent NNS cord-015569-vy49r1zd 208 26 , , , cord-015569-vy49r1zd 208 27 hormones hormone NNS cord-015569-vy49r1zd 208 28 and and CC cord-015569-vy49r1zd 208 29 tastants tastant NNS cord-015569-vy49r1zd 208 30 . . . cord-015569-vy49r1zd 209 1 We -PRON- PRP cord-015569-vy49r1zd 209 2 concluded conclude VBD cord-015569-vy49r1zd 209 3 that that IN cord-015569-vy49r1zd 209 4 this this DT cord-015569-vy49r1zd 209 5 technique technique NN cord-015569-vy49r1zd 209 6 could could MD cord-015569-vy49r1zd 209 7 be be VB cord-015569-vy49r1zd 209 8 used use VBN cord-015569-vy49r1zd 209 9 to to TO cord-015569-vy49r1zd 209 10 determine determine VB cord-015569-vy49r1zd 209 11 the the DT cord-015569-vy49r1zd 209 12 effect effect NN cord-015569-vy49r1zd 209 13 of of IN cord-015569-vy49r1zd 209 14 physiological physiological JJ cord-015569-vy49r1zd 209 15 , , , cord-015569-vy49r1zd 209 16 pharmacological pharmacological JJ cord-015569-vy49r1zd 209 17 and and CC cord-015569-vy49r1zd 209 18 nutritional nutritional JJ cord-015569-vy49r1zd 209 19 intervention intervention NN cord-015569-vy49r1zd 209 20 on on IN cord-015569-vy49r1zd 209 21 the the DT cord-015569-vy49r1zd 209 22 motility motility NN cord-015569-vy49r1zd 209 23 of of IN cord-015569-vy49r1zd 209 24 the the DT cord-015569-vy49r1zd 209 25 gastrointestinal gastrointestinal JJ cord-015569-vy49r1zd 209 26 tract tract NN cord-015569-vy49r1zd 209 27 . . . cord-015569-vy49r1zd 210 1 In in IN cord-015569-vy49r1zd 210 2 oral oral JJ cord-015569-vy49r1zd 210 3 surgery surgery NN cord-015569-vy49r1zd 210 4 treatments treatment NNS cord-015569-vy49r1zd 210 5 , , , cord-015569-vy49r1zd 210 6 acrinol acrinol NNP cord-015569-vy49r1zd 210 7 hydrate hydrate NNP cord-015569-vy49r1zd 210 8 is be VBZ cord-015569-vy49r1zd 210 9 often often RB cord-015569-vy49r1zd 210 10 used use VBN cord-015569-vy49r1zd 210 11 as as IN cord-015569-vy49r1zd 210 12 a a DT cord-015569-vy49r1zd 210 13 disinfectant disinfectant NN cord-015569-vy49r1zd 210 14 for for IN cord-015569-vy49r1zd 210 15 oral oral JJ cord-015569-vy49r1zd 210 16 membranes membrane NNS cord-015569-vy49r1zd 210 17 ; ; : cord-015569-vy49r1zd 210 18 however however RB cord-015569-vy49r1zd 210 19 , , , cord-015569-vy49r1zd 210 20 there there EX cord-015569-vy49r1zd 210 21 are be VBP cord-015569-vy49r1zd 210 22 few few JJ cord-015569-vy49r1zd 210 23 reports report NNS cord-015569-vy49r1zd 210 24 about about IN cord-015569-vy49r1zd 210 25 the the DT cord-015569-vy49r1zd 210 26 effect effect NN cord-015569-vy49r1zd 210 27 on on IN cord-015569-vy49r1zd 210 28 taste taste NN cord-015569-vy49r1zd 210 29 nerve nerve NN cord-015569-vy49r1zd 210 30 response response NN cord-015569-vy49r1zd 210 31 to to IN cord-015569-vy49r1zd 210 32 this this DT cord-015569-vy49r1zd 210 33 disinfectant disinfectant NN cord-015569-vy49r1zd 210 34 . . . cord-015569-vy49r1zd 211 1 In in IN cord-015569-vy49r1zd 211 2 this this DT cord-015569-vy49r1zd 211 3 study study NN cord-015569-vy49r1zd 211 4 , , , cord-015569-vy49r1zd 211 5 we -PRON- PRP cord-015569-vy49r1zd 211 6 tested test VBD cord-015569-vy49r1zd 211 7 if if IN cord-015569-vy49r1zd 211 8 tongue tongue NN cord-015569-vy49r1zd 211 9 treatment treatment NN cord-015569-vy49r1zd 211 10 with with IN cord-015569-vy49r1zd 211 11 acrinol acrinol NNP cord-015569-vy49r1zd 211 12 hydrate hydrate NNP cord-015569-vy49r1zd 211 13 affects affect VBZ cord-015569-vy49r1zd 211 14 taste taste VBP cord-015569-vy49r1zd 211 15 nerve nerve NN cord-015569-vy49r1zd 211 16 responses response NNS cord-015569-vy49r1zd 211 17 in in IN cord-015569-vy49r1zd 211 18 mice mouse NNS cord-015569-vy49r1zd 211 19 . . . cord-015569-vy49r1zd 212 1 The the DT cord-015569-vy49r1zd 212 2 chorda chorda NN cord-015569-vy49r1zd 212 3 tympani tympani NN cord-015569-vy49r1zd 212 4 nerve nerve NN cord-015569-vy49r1zd 212 5 responses response NNS cord-015569-vy49r1zd 212 6 of of IN cord-015569-vy49r1zd 212 7 C57BL/6 C57BL/6 NNP cord-015569-vy49r1zd 212 8 mice mouse NNS cord-015569-vy49r1zd 212 9 to to TO cord-015569-vy49r1zd 212 10 5 5 CD cord-015569-vy49r1zd 212 11 basic basic JJ cord-015569-vy49r1zd 212 12 taste taste NN cord-015569-vy49r1zd 212 13 stimuli stimulus NNS cord-015569-vy49r1zd 212 14 before before IN cord-015569-vy49r1zd 212 15 and and CC cord-015569-vy49r1zd 212 16 after after IN cord-015569-vy49r1zd 212 17 treatment treatment NN cord-015569-vy49r1zd 212 18 with with IN cord-015569-vy49r1zd 212 19 acrinol acrinol NNP cord-015569-vy49r1zd 212 20 hydrate hydrate NNP cord-015569-vy49r1zd 212 21 were be VBD cord-015569-vy49r1zd 212 22 recorded record VBN cord-015569-vy49r1zd 212 23 and and CC cord-015569-vy49r1zd 212 24 compared compare VBN cord-015569-vy49r1zd 212 25 . . . cord-015569-vy49r1zd 213 1 The the DT cord-015569-vy49r1zd 213 2 results result NNS cord-015569-vy49r1zd 213 3 of of IN cord-015569-vy49r1zd 213 4 the the DT cord-015569-vy49r1zd 213 5 treatment treatment NN cord-015569-vy49r1zd 213 6 with with IN cord-015569-vy49r1zd 213 7 acrinol acrinol NNP cord-015569-vy49r1zd 213 8 hydrate hydrate NNP cord-015569-vy49r1zd 213 9 indicated indicate VBD cord-015569-vy49r1zd 213 10 that that IN cord-015569-vy49r1zd 213 11 the the DT cord-015569-vy49r1zd 213 12 chorda chorda NNP cord-015569-vy49r1zd 213 13 tympani tympani NNP cord-015569-vy49r1zd 213 14 nerve nerve NN cord-015569-vy49r1zd 213 15 response response NN cord-015569-vy49r1zd 213 16 to to IN cord-015569-vy49r1zd 213 17 0.5 0.5 CD cord-015569-vy49r1zd 213 18 M M NNP cord-015569-vy49r1zd 213 19 sucrose sucrose NN cord-015569-vy49r1zd 213 20 was be VBD cord-015569-vy49r1zd 213 21 suppressed suppress VBN cord-015569-vy49r1zd 213 22 by by IN cord-015569-vy49r1zd 213 23 60 60 CD cord-015569-vy49r1zd 213 24 % % NN cord-015569-vy49r1zd 213 25 ; ; , cord-015569-vy49r1zd 213 26 however however RB cord-015569-vy49r1zd 213 27 , , , cord-015569-vy49r1zd 213 28 there there EX cord-015569-vy49r1zd 213 29 was be VBD cord-015569-vy49r1zd 213 30 no no DT cord-015569-vy49r1zd 213 31 change change NN cord-015569-vy49r1zd 213 32 in in IN cord-015569-vy49r1zd 213 33 the the DT cord-015569-vy49r1zd 213 34 responses response NNS cord-015569-vy49r1zd 213 35 to to IN cord-015569-vy49r1zd 213 36 0.1 0.1 CD cord-015569-vy49r1zd 213 37 M M NNP cord-015569-vy49r1zd 213 38 NaCl nacl NN cord-015569-vy49r1zd 213 39 , , , cord-015569-vy49r1zd 213 40 0.01 0.01 CD cord-015569-vy49r1zd 213 41 M M NNP cord-015569-vy49r1zd 213 42 HCl HCl NNP cord-015569-vy49r1zd 213 43 , , , cord-015569-vy49r1zd 213 44 0.02 0.02 CD cord-015569-vy49r1zd 213 45 M m CD cord-015569-vy49r1zd 213 46 quinine quinine NN cord-015569-vy49r1zd 213 47 hydrochloride hydrochloride NN cord-015569-vy49r1zd 213 48 and and CC cord-015569-vy49r1zd 213 49 0.1 0.1 CD cord-015569-vy49r1zd 213 50 M m NN cord-015569-vy49r1zd 213 51 monopotassium monopotassium NN cord-015569-vy49r1zd 213 52 glutamate glutamate NN cord-015569-vy49r1zd 213 53 . . . cord-015569-vy49r1zd 214 1 The the DT cord-015569-vy49r1zd 214 2 suppression suppression NN cord-015569-vy49r1zd 214 3 of of IN cord-015569-vy49r1zd 214 4 the the DT cord-015569-vy49r1zd 214 5 sucrose sucrose NN cord-015569-vy49r1zd 214 6 response response NN cord-015569-vy49r1zd 214 7 by by IN cord-015569-vy49r1zd 214 8 this this DT cord-015569-vy49r1zd 214 9 treatment treatment NN cord-015569-vy49r1zd 214 10 recovered recover VBD cord-015569-vy49r1zd 214 11 within within IN cord-015569-vy49r1zd 214 12 1 1 CD cord-015569-vy49r1zd 214 13 minute minute NN cord-015569-vy49r1zd 214 14 after after IN cord-015569-vy49r1zd 214 15 washing washing NN cord-015569-vy49r1zd 214 16 . . . cord-015569-vy49r1zd 215 1 These these DT cord-015569-vy49r1zd 215 2 results result NNS cord-015569-vy49r1zd 215 3 suggest suggest VBP cord-015569-vy49r1zd 215 4 that that IN cord-015569-vy49r1zd 215 5 acrinol acrinol NNP cord-015569-vy49r1zd 215 6 hydrate hydrate NNP cord-015569-vy49r1zd 215 7 has have VBZ cord-015569-vy49r1zd 215 8 an an DT cord-015569-vy49r1zd 215 9 ability ability NN cord-015569-vy49r1zd 215 10 to to TO cord-015569-vy49r1zd 215 11 suppress suppress VB cord-015569-vy49r1zd 215 12 sweet sweet JJ cord-015569-vy49r1zd 215 13 taste taste NN cord-015569-vy49r1zd 215 14 . . . cord-015569-vy49r1zd 216 1 Some some DT cord-015569-vy49r1zd 216 2 mints mint NNS cord-015569-vy49r1zd 216 3 , , , cord-015569-vy49r1zd 216 4 such such JJ cord-015569-vy49r1zd 216 5 as as IN cord-015569-vy49r1zd 216 6 peppermint peppermint NN cord-015569-vy49r1zd 216 7 , , , cord-015569-vy49r1zd 216 8 are be VBP cord-015569-vy49r1zd 216 9 used use VBN cord-015569-vy49r1zd 216 10 as as IN cord-015569-vy49r1zd 216 11 flavoring flavor VBG cord-015569-vy49r1zd 216 12 substances substance NNS cord-015569-vy49r1zd 216 13 for for IN cord-015569-vy49r1zd 216 14 foods food NNS cord-015569-vy49r1zd 216 15 and and CC cord-015569-vy49r1zd 216 16 toothpaste toothpaste NN cord-015569-vy49r1zd 216 17 widely widely RB cord-015569-vy49r1zd 216 18 . . . cord-015569-vy49r1zd 217 1 However however RB cord-015569-vy49r1zd 217 2 , , , cord-015569-vy49r1zd 217 3 it -PRON- PRP cord-015569-vy49r1zd 217 4 is be VBZ cord-015569-vy49r1zd 217 5 not not RB cord-015569-vy49r1zd 217 6 clear clear JJ cord-015569-vy49r1zd 217 7 whether whether IN cord-015569-vy49r1zd 217 8 mints mint NNS cord-015569-vy49r1zd 217 9 affect affect VBP cord-015569-vy49r1zd 217 10 the the DT cord-015569-vy49r1zd 217 11 taste taste NN cord-015569-vy49r1zd 217 12 receptor receptor NN cord-015569-vy49r1zd 217 13 mechanisms mechanism NNS cord-015569-vy49r1zd 217 14 or or CC cord-015569-vy49r1zd 217 15 not not RB cord-015569-vy49r1zd 217 16 . . . cord-015569-vy49r1zd 218 1 In in IN cord-015569-vy49r1zd 218 2 the the DT cord-015569-vy49r1zd 218 3 present present JJ cord-015569-vy49r1zd 218 4 study study NN cord-015569-vy49r1zd 218 5 , , , cord-015569-vy49r1zd 218 6 therefore therefore RB cord-015569-vy49r1zd 218 7 , , , cord-015569-vy49r1zd 218 8 the the DT cord-015569-vy49r1zd 218 9 chorda chorda NNP cord-015569-vy49r1zd 218 10 tympani tympani NN cord-015569-vy49r1zd 218 11 nerve nerve NN cord-015569-vy49r1zd 218 12 responses response NNS cord-015569-vy49r1zd 218 13 to to IN cord-015569-vy49r1zd 218 14 5 5 CD cord-015569-vy49r1zd 218 15 basic basic JJ cord-015569-vy49r1zd 218 16 tastes taste NNS cord-015569-vy49r1zd 218 17 were be VBD cord-015569-vy49r1zd 218 18 compared compare VBN cord-015569-vy49r1zd 218 19 before before IN cord-015569-vy49r1zd 218 20 and and CC cord-015569-vy49r1zd 218 21 after after IN cord-015569-vy49r1zd 218 22 mixing mix VBG cord-015569-vy49r1zd 218 23 with with IN cord-015569-vy49r1zd 218 24 3 3 CD cord-015569-vy49r1zd 218 25 types type NNS cord-015569-vy49r1zd 218 26 of of IN cord-015569-vy49r1zd 218 27 mints mint NNS cord-015569-vy49r1zd 218 28 , , , cord-015569-vy49r1zd 218 29 such such JJ cord-015569-vy49r1zd 218 30 as as IN cord-015569-vy49r1zd 218 31 0.18 0.18 CD cord-015569-vy49r1zd 218 32 % % NN cord-015569-vy49r1zd 218 33 peppermint peppermint NN cord-015569-vy49r1zd 218 34 , , , cord-015569-vy49r1zd 218 35 0.18 0.18 CD cord-015569-vy49r1zd 218 36 % % NN cord-015569-vy49r1zd 218 37 spearmint spearmint NN cord-015569-vy49r1zd 218 38 and and CC cord-015569-vy49r1zd 218 39 0.10 0.10 CD cord-015569-vy49r1zd 218 40 % % NN cord-015569-vy49r1zd 218 41 menthol menthol NN cord-015569-vy49r1zd 218 42 , , , cord-015569-vy49r1zd 218 43 in in IN cord-015569-vy49r1zd 218 44 C57BL/6 C57BL/6 NNP cord-015569-vy49r1zd 218 45 mice mouse NNS cord-015569-vy49r1zd 218 46 . . . cord-015569-vy49r1zd 219 1 When when WRB cord-015569-vy49r1zd 219 2 spearmint spearmint NN cord-015569-vy49r1zd 219 3 was be VBD cord-015569-vy49r1zd 219 4 mixed mix VBN cord-015569-vy49r1zd 219 5 with with IN cord-015569-vy49r1zd 219 6 0.5 0.5 CD cord-015569-vy49r1zd 219 7 M M NNP cord-015569-vy49r1zd 219 8 sucrose sucrose NN cord-015569-vy49r1zd 219 9 , , , cord-015569-vy49r1zd 219 10 20 20 CD cord-015569-vy49r1zd 219 11 mM mm CD cord-015569-vy49r1zd 219 12 denatonium denatonium NN cord-015569-vy49r1zd 219 13 benzoate benzoate NN cord-015569-vy49r1zd 219 14 , , , cord-015569-vy49r1zd 219 15 0.1 0.1 CD cord-015569-vy49r1zd 219 16 M m NN cord-015569-vy49r1zd 219 17 monopotassium monopotassium NN cord-015569-vy49r1zd 219 18 glutamate glutamate NN cord-015569-vy49r1zd 219 19 ( ( -LRB- cord-015569-vy49r1zd 219 20 MPG MPG NNP cord-015569-vy49r1zd 219 21 ) ) -RRB- cord-015569-vy49r1zd 219 22 , , , cord-015569-vy49r1zd 219 23 5 5 CD cord-015569-vy49r1zd 219 24 mM mm NN cord-015569-vy49r1zd 219 25 5#-inositol 5#-inositol CD cord-015569-vy49r1zd 219 26 monophosphate monophosphate NN cord-015569-vy49r1zd 219 27 ( ( -LRB- cord-015569-vy49r1zd 219 28 IMP IMP NNP cord-015569-vy49r1zd 219 29 ) ) -RRB- cord-015569-vy49r1zd 219 30 and and CC cord-015569-vy49r1zd 219 31 the the DT cord-015569-vy49r1zd 219 32 mixture mixture NN cord-015569-vy49r1zd 219 33 of of IN cord-015569-vy49r1zd 219 34 0.1 0.1 CD cord-015569-vy49r1zd 219 35 M m NN cord-015569-vy49r1zd 219 36 MPG MPG NNP cord-015569-vy49r1zd 219 37 and and CC cord-015569-vy49r1zd 219 38 5 5 CD cord-015569-vy49r1zd 219 39 mM mm CD cord-015569-vy49r1zd 219 40 IMP imp NN cord-015569-vy49r1zd 219 41 ( ( -LRB- cord-015569-vy49r1zd 219 42 M+I M+I NNP cord-015569-vy49r1zd 219 43 ) ) -RRB- cord-015569-vy49r1zd 219 44 , , , cord-015569-vy49r1zd 219 45 the the DT cord-015569-vy49r1zd 219 46 neural neural JJ cord-015569-vy49r1zd 219 47 responses response NNS cord-015569-vy49r1zd 219 48 to to IN cord-015569-vy49r1zd 219 49 these these DT cord-015569-vy49r1zd 219 50 stimuli stimulus NNS cord-015569-vy49r1zd 219 51 were be VBD cord-015569-vy49r1zd 219 52 suppressed suppress VBN cord-015569-vy49r1zd 219 53 . . . cord-015569-vy49r1zd 220 1 But but CC cord-015569-vy49r1zd 220 2 mixing mix VBG cord-015569-vy49r1zd 220 3 of of IN cord-015569-vy49r1zd 220 4 spearmint spearmint NN cord-015569-vy49r1zd 220 5 did do VBD cord-015569-vy49r1zd 220 6 not not RB cord-015569-vy49r1zd 220 7 change change VB cord-015569-vy49r1zd 220 8 the the DT cord-015569-vy49r1zd 220 9 responses response NNS cord-015569-vy49r1zd 220 10 to to IN cord-015569-vy49r1zd 220 11 0.1 0.1 CD cord-015569-vy49r1zd 220 12 M M NNP cord-015569-vy49r1zd 220 13 NaCl nacl NN cord-015569-vy49r1zd 220 14 , , , cord-015569-vy49r1zd 220 15 20 20 CD cord-015569-vy49r1zd 220 16 mM mm CD cord-015569-vy49r1zd 220 17 quinine quinine NN cord-015569-vy49r1zd 220 18 - - HYPH cord-015569-vy49r1zd 220 19 hydrochloride hydrochloride NN cord-015569-vy49r1zd 220 20 and and CC cord-015569-vy49r1zd 220 21 10 10 CD cord-015569-vy49r1zd 220 22 mM mm CD cord-015569-vy49r1zd 220 23 HCl hcl NN cord-015569-vy49r1zd 220 24 . . . cord-015569-vy49r1zd 221 1 Mixing mix VBG cord-015569-vy49r1zd 221 2 of of IN cord-015569-vy49r1zd 221 3 peppermint peppermint NN cord-015569-vy49r1zd 221 4 or or CC cord-015569-vy49r1zd 221 5 menthol menthol NN cord-015569-vy49r1zd 221 6 did do VBD cord-015569-vy49r1zd 221 7 not not RB cord-015569-vy49r1zd 221 8 change change VB cord-015569-vy49r1zd 221 9 any any DT cord-015569-vy49r1zd 221 10 responses response NNS cord-015569-vy49r1zd 221 11 to to IN cord-015569-vy49r1zd 221 12 all all DT cord-015569-vy49r1zd 221 13 tested test VBN cord-015569-vy49r1zd 221 14 stimuli stimulus NNS cord-015569-vy49r1zd 221 15 in in IN cord-015569-vy49r1zd 221 16 the the DT cord-015569-vy49r1zd 221 17 present present JJ cord-015569-vy49r1zd 221 18 study study NN cord-015569-vy49r1zd 221 19 . . . cord-015569-vy49r1zd 222 1 These these DT cord-015569-vy49r1zd 222 2 results result NNS cord-015569-vy49r1zd 222 3 suggest suggest VBP cord-015569-vy49r1zd 222 4 that that IN cord-015569-vy49r1zd 222 5 spearmint spearmint NN cord-015569-vy49r1zd 222 6 may may MD cord-015569-vy49r1zd 222 7 work work VB cord-015569-vy49r1zd 222 8 as as IN cord-015569-vy49r1zd 222 9 a a DT cord-015569-vy49r1zd 222 10 suppressant suppressant NN cord-015569-vy49r1zd 222 11 for for IN cord-015569-vy49r1zd 222 12 some some DT cord-015569-vy49r1zd 222 13 kind kind NN cord-015569-vy49r1zd 222 14 of of IN cord-015569-vy49r1zd 222 15 receptors receptor NNS cord-015569-vy49r1zd 222 16 for for IN cord-015569-vy49r1zd 222 17 sweet sweet JJ cord-015569-vy49r1zd 222 18 , , , cord-015569-vy49r1zd 222 19 umami umami NN cord-015569-vy49r1zd 222 20 and and CC cord-015569-vy49r1zd 222 21 bitter bitter JJ cord-015569-vy49r1zd 222 22 . . . cord-015569-vy49r1zd 223 1 The the DT cord-015569-vy49r1zd 223 2 majority majority NN cord-015569-vy49r1zd 223 3 of of IN cord-015569-vy49r1zd 223 4 the the DT cord-015569-vy49r1zd 223 5 experiments experiment NNS cord-015569-vy49r1zd 223 6 for for IN cord-015569-vy49r1zd 223 7 investigating investigate VBG cord-015569-vy49r1zd 223 8 gustatory gustatory JJ cord-015569-vy49r1zd 223 9 information information NN cord-015569-vy49r1zd 223 10 processing processing NN cord-015569-vy49r1zd 223 11 in in IN cord-015569-vy49r1zd 223 12 the the DT cord-015569-vy49r1zd 223 13 nucleus nucleus NN cord-015569-vy49r1zd 223 14 of of IN cord-015569-vy49r1zd 223 15 the the DT cord-015569-vy49r1zd 223 16 solitary solitary JJ cord-015569-vy49r1zd 223 17 tract tract NN cord-015569-vy49r1zd 223 18 ( ( -LRB- cord-015569-vy49r1zd 223 19 NST NST NNP cord-015569-vy49r1zd 223 20 ) ) -RRB- cord-015569-vy49r1zd 223 21 have have VBP cord-015569-vy49r1zd 223 22 been be VBN cord-015569-vy49r1zd 223 23 performed perform VBN cord-015569-vy49r1zd 223 24 using use VBG cord-015569-vy49r1zd 223 25 rats rat NNS cord-015569-vy49r1zd 223 26 as as IN cord-015569-vy49r1zd 223 27 experimental experimental JJ cord-015569-vy49r1zd 223 28 animals animal NNS cord-015569-vy49r1zd 223 29 . . . cord-015569-vy49r1zd 224 1 Although although IN cord-015569-vy49r1zd 224 2 the the DT cord-015569-vy49r1zd 224 3 importance importance NN cord-015569-vy49r1zd 224 4 of of IN cord-015569-vy49r1zd 224 5 mice mouse NNS cord-015569-vy49r1zd 224 6 in in IN cord-015569-vy49r1zd 224 7 this this DT cord-015569-vy49r1zd 224 8 kind kind NN cord-015569-vy49r1zd 224 9 of of IN cord-015569-vy49r1zd 224 10 study study NN cord-015569-vy49r1zd 224 11 is be VBZ cord-015569-vy49r1zd 224 12 widely widely RB cord-015569-vy49r1zd 224 13 recognized recognize VBN cord-015569-vy49r1zd 224 14 from from IN cord-015569-vy49r1zd 224 15 the the DT cord-015569-vy49r1zd 224 16 view view NN cord-015569-vy49r1zd 224 17 point point NN cord-015569-vy49r1zd 224 18 of of IN cord-015569-vy49r1zd 224 19 recent recent JJ cord-015569-vy49r1zd 224 20 , , , cord-015569-vy49r1zd 224 21 rapid rapid JJ cord-015569-vy49r1zd 224 22 advance advance NN cord-015569-vy49r1zd 224 23 in in IN cord-015569-vy49r1zd 224 24 gene gene NN cord-015569-vy49r1zd 224 25 manipulation manipulation NN cord-015569-vy49r1zd 224 26 techniques technique NNS cord-015569-vy49r1zd 224 27 , , , cord-015569-vy49r1zd 224 28 there there EX cord-015569-vy49r1zd 224 29 are be VBP cord-015569-vy49r1zd 224 30 very very RB cord-015569-vy49r1zd 224 31 few few JJ cord-015569-vy49r1zd 224 32 studies study NNS cord-015569-vy49r1zd 224 33 using use VBG cord-015569-vy49r1zd 224 34 mice mouse NNS cord-015569-vy49r1zd 224 35 in in IN cord-015569-vy49r1zd 224 36 this this DT cord-015569-vy49r1zd 224 37 academic academic JJ cord-015569-vy49r1zd 224 38 field field NN cord-015569-vy49r1zd 224 39 . . . cord-015569-vy49r1zd 225 1 Also also RB cord-015569-vy49r1zd 225 2 , , , cord-015569-vy49r1zd 225 3 it -PRON- PRP cord-015569-vy49r1zd 225 4 is be VBZ cord-015569-vy49r1zd 225 5 desirable desirable JJ cord-015569-vy49r1zd 225 6 for for IN cord-015569-vy49r1zd 225 7 physiological physiological JJ cord-015569-vy49r1zd 225 8 studies study NNS cord-015569-vy49r1zd 225 9 on on IN cord-015569-vy49r1zd 225 10 neural neural JJ cord-015569-vy49r1zd 225 11 mechanisms mechanism NNS cord-015569-vy49r1zd 225 12 of of IN cord-015569-vy49r1zd 225 13 taste taste NN cord-015569-vy49r1zd 225 14 perception perception NN cord-015569-vy49r1zd 225 15 to to TO cord-015569-vy49r1zd 225 16 use use VB cord-015569-vy49r1zd 225 17 awake awake JJ cord-015569-vy49r1zd 225 18 , , , cord-015569-vy49r1zd 225 19 or or CC cord-015569-vy49r1zd 225 20 at at IN cord-015569-vy49r1zd 225 21 least least JJS cord-015569-vy49r1zd 225 22 , , , cord-015569-vy49r1zd 225 23 weakly weakly RB cord-015569-vy49r1zd 225 24 anesthetized anesthetize VBN cord-015569-vy49r1zd 225 25 animals animal NNS cord-015569-vy49r1zd 225 26 . . . cord-015569-vy49r1zd 226 1 Therefore therefore RB cord-015569-vy49r1zd 226 2 , , , cord-015569-vy49r1zd 226 3 in in IN cord-015569-vy49r1zd 226 4 the the DT cord-015569-vy49r1zd 226 5 present present JJ cord-015569-vy49r1zd 226 6 study study NN cord-015569-vy49r1zd 226 7 we -PRON- PRP cord-015569-vy49r1zd 226 8 tried try VBD cord-015569-vy49r1zd 226 9 to to TO cord-015569-vy49r1zd 226 10 establish establish VB cord-015569-vy49r1zd 226 11 an an DT cord-015569-vy49r1zd 226 12 experimental experimental JJ cord-015569-vy49r1zd 226 13 model model NN cord-015569-vy49r1zd 226 14 for for IN cord-015569-vy49r1zd 226 15 in in IN cord-015569-vy49r1zd 226 16 vivo vivo NN cord-015569-vy49r1zd 226 17 recording recording NN cord-015569-vy49r1zd 226 18 of of IN cord-015569-vy49r1zd 226 19 NST NST NNP cord-015569-vy49r1zd 226 20 neurons neuron NNS cord-015569-vy49r1zd 226 21 in in IN cord-015569-vy49r1zd 226 22 slightly slightly RB cord-015569-vy49r1zd 226 23 anesthetized anesthetized JJ cord-015569-vy49r1zd 226 24 or or CC cord-015569-vy49r1zd 226 25 awake awake JJ cord-015569-vy49r1zd 226 26 mice mouse NNS cord-015569-vy49r1zd 226 27 . . . cord-015569-vy49r1zd 227 1 For for IN cord-015569-vy49r1zd 227 2 this this DT cord-015569-vy49r1zd 227 3 , , , cord-015569-vy49r1zd 227 4 we -PRON- PRP cord-015569-vy49r1zd 227 5 surgically surgically RB cord-015569-vy49r1zd 227 6 fixed fix VBD cord-015569-vy49r1zd 227 7 a a DT cord-015569-vy49r1zd 227 8 head head NN cord-015569-vy49r1zd 227 9 restraining restrain VBG cord-015569-vy49r1zd 227 10 holder holder NN cord-015569-vy49r1zd 227 11 to to IN cord-015569-vy49r1zd 227 12 the the DT cord-015569-vy49r1zd 227 13 mouse mouse NN cord-015569-vy49r1zd 227 14 scull scull NN cord-015569-vy49r1zd 227 15 , , , cord-015569-vy49r1zd 227 16 which which WDT cord-015569-vy49r1zd 227 17 made make VBD cord-015569-vy49r1zd 227 18 it -PRON- PRP cord-015569-vy49r1zd 227 19 possible possible JJ cord-015569-vy49r1zd 227 20 to to TO cord-015569-vy49r1zd 227 21 place place VB cord-015569-vy49r1zd 227 22 the the DT cord-015569-vy49r1zd 227 23 mouse mouse NN cord-015569-vy49r1zd 227 24 head head NN cord-015569-vy49r1zd 227 25 precisely precisely RB cord-015569-vy49r1zd 227 26 in in IN cord-015569-vy49r1zd 227 27 a a DT cord-015569-vy49r1zd 227 28 stereotaxic stereotaxic JJ cord-015569-vy49r1zd 227 29 position position NN cord-015569-vy49r1zd 227 30 repeatedly repeatedly RB cord-015569-vy49r1zd 227 31 without without IN cord-015569-vy49r1zd 227 32 pain pain NN cord-015569-vy49r1zd 227 33 . . . cord-015569-vy49r1zd 228 1 After after IN cord-015569-vy49r1zd 228 2 the the DT cord-015569-vy49r1zd 228 3 recovery recovery NN cord-015569-vy49r1zd 228 4 from from IN cord-015569-vy49r1zd 228 5 this this DT cord-015569-vy49r1zd 228 6 surgery surgery NN cord-015569-vy49r1zd 228 7 , , , cord-015569-vy49r1zd 228 8 the the DT cord-015569-vy49r1zd 228 9 gustatory gustatory JJ cord-015569-vy49r1zd 228 10 area area NN cord-015569-vy49r1zd 228 11 in in IN cord-015569-vy49r1zd 228 12 the the DT cord-015569-vy49r1zd 228 13 NST NST NNP cord-015569-vy49r1zd 228 14 was be VBD cord-015569-vy49r1zd 228 15 localized localize VBN cord-015569-vy49r1zd 228 16 electrophysiologically electrophysiologically RB cord-015569-vy49r1zd 228 17 under under IN cord-015569-vy49r1zd 228 18 anesthesia anesthesia NN cord-015569-vy49r1zd 228 19 . . . cord-015569-vy49r1zd 229 1 Then then RB cord-015569-vy49r1zd 229 2 , , , cord-015569-vy49r1zd 229 3 single single JJ cord-015569-vy49r1zd 229 4 neuron neuron NN cord-015569-vy49r1zd 229 5 activity activity NN cord-015569-vy49r1zd 229 6 was be VBD cord-015569-vy49r1zd 229 7 recorded record VBN cord-015569-vy49r1zd 229 8 in in IN cord-015569-vy49r1zd 229 9 this this DT cord-015569-vy49r1zd 229 10 area area NN cord-015569-vy49r1zd 229 11 under under IN cord-015569-vy49r1zd 229 12 slight slight JJ cord-015569-vy49r1zd 229 13 anesthesia anesthesia NN cord-015569-vy49r1zd 229 14 , , , cord-015569-vy49r1zd 229 15 and and CC cord-015569-vy49r1zd 229 16 responsiveness responsiveness NN cord-015569-vy49r1zd 229 17 to to IN cord-015569-vy49r1zd 229 18 4 4 CD cord-015569-vy49r1zd 229 19 standard standard JJ cord-015569-vy49r1zd 229 20 taste taste NN cord-015569-vy49r1zd 229 21 solutions solution NNS cord-015569-vy49r1zd 229 22 ( ( -LRB- cord-015569-vy49r1zd 229 23 NaCl nacl NN cord-015569-vy49r1zd 229 24 , , , cord-015569-vy49r1zd 229 25 sucrose sucrose NN cord-015569-vy49r1zd 229 26 , , , cord-015569-vy49r1zd 229 27 citric citric NN cord-015569-vy49r1zd 229 28 acid acid NN cord-015569-vy49r1zd 229 29 and and CC cord-015569-vy49r1zd 229 30 quinine quinine NN cord-015569-vy49r1zd 229 31 HCl HCl NNP cord-015569-vy49r1zd 229 32 ) ) -RRB- cord-015569-vy49r1zd 229 33 was be VBD cord-015569-vy49r1zd 229 34 tested test VBN cord-015569-vy49r1zd 229 35 . . . cord-015569-vy49r1zd 230 1 As as IN cord-015569-vy49r1zd 230 2 a a DT cord-015569-vy49r1zd 230 3 result result NN cord-015569-vy49r1zd 230 4 , , , cord-015569-vy49r1zd 230 5 9 9 CD cord-015569-vy49r1zd 230 6 gustatory gustatory JJ cord-015569-vy49r1zd 230 7 neurons neuron NNS cord-015569-vy49r1zd 230 8 were be VBD cord-015569-vy49r1zd 230 9 recorded record VBN cord-015569-vy49r1zd 230 10 ; ; : cord-015569-vy49r1zd 230 11 of of IN cord-015569-vy49r1zd 230 12 these these DT cord-015569-vy49r1zd 230 13 , , , cord-015569-vy49r1zd 230 14 4 4 CD cord-015569-vy49r1zd 230 15 , , , cord-015569-vy49r1zd 230 16 4 4 CD cord-015569-vy49r1zd 230 17 and and CC cord-015569-vy49r1zd 230 18 1 1 CD cord-015569-vy49r1zd 230 19 neurons neuron NNS cord-015569-vy49r1zd 230 20 were be VBD cord-015569-vy49r1zd 230 21 classified classify VBN cord-015569-vy49r1zd 230 22 into into IN cord-015569-vy49r1zd 230 23 NaCl nacl NN cord-015569-vy49r1zd 230 24 - - HYPH cord-015569-vy49r1zd 230 25 best good JJS cord-015569-vy49r1zd 230 26 , , , cord-015569-vy49r1zd 230 27 sucrose sucrose NN cord-015569-vy49r1zd 230 28 - - HYPH cord-015569-vy49r1zd 230 29 best good JJS cord-015569-vy49r1zd 230 30 and and CC cord-015569-vy49r1zd 230 31 citric citric JJ cord-015569-vy49r1zd 230 32 acid acid NN cord-015569-vy49r1zd 230 33 - - HYPH cord-015569-vy49r1zd 230 34 best good JJS cord-015569-vy49r1zd 230 35 , , , cord-015569-vy49r1zd 230 36 respectively respectively RB cord-015569-vy49r1zd 230 37 . . . cord-015569-vy49r1zd 231 1 Furthermore furthermore RB cord-015569-vy49r1zd 231 2 , , , cord-015569-vy49r1zd 231 3 we -PRON- PRP cord-015569-vy49r1zd 231 4 found find VBD cord-015569-vy49r1zd 231 5 that that IN cord-015569-vy49r1zd 231 6 the the DT cord-015569-vy49r1zd 231 7 mouse mouse NN cord-015569-vy49r1zd 231 8 could could MD cord-015569-vy49r1zd 231 9 be be VB cord-015569-vy49r1zd 231 10 easily easily RB cord-015569-vy49r1zd 231 11 trained train VBN cord-015569-vy49r1zd 231 12 to to TO cord-015569-vy49r1zd 231 13 lick lick VB cord-015569-vy49r1zd 231 14 taste taste NN cord-015569-vy49r1zd 231 15 stimuli stimulus NNS cord-015569-vy49r1zd 231 16 with with IN cord-015569-vy49r1zd 231 17 the the DT cord-015569-vy49r1zd 231 18 head head NN cord-015569-vy49r1zd 231 19 restrained restrain VBN cord-015569-vy49r1zd 231 20 in in IN cord-015569-vy49r1zd 231 21 the the DT cord-015569-vy49r1zd 231 22 stereotaxic stereotaxic NNP cord-015569-vy49r1zd 231 23 device device NN cord-015569-vy49r1zd 231 24 . . . cord-015569-vy49r1zd 232 1 These these DT cord-015569-vy49r1zd 232 2 results result NNS cord-015569-vy49r1zd 232 3 indicate indicate VBP cord-015569-vy49r1zd 232 4 that that IN cord-015569-vy49r1zd 232 5 the the DT cord-015569-vy49r1zd 232 6 present present JJ cord-015569-vy49r1zd 232 7 method method NN cord-015569-vy49r1zd 232 8 is be VBZ cord-015569-vy49r1zd 232 9 applicable applicable JJ cord-015569-vy49r1zd 232 10 to to IN cord-015569-vy49r1zd 232 11 the the DT cord-015569-vy49r1zd 232 12 investigation investigation NN cord-015569-vy49r1zd 232 13 of of IN cord-015569-vy49r1zd 232 14 gustatory gustatory JJ cord-015569-vy49r1zd 232 15 information information NN cord-015569-vy49r1zd 232 16 processing processing NN cord-015569-vy49r1zd 232 17 in in IN cord-015569-vy49r1zd 232 18 the the DT cord-015569-vy49r1zd 232 19 NST NST NNP cord-015569-vy49r1zd 232 20 of of IN cord-015569-vy49r1zd 232 21 mice mouse NNS cord-015569-vy49r1zd 232 22 under under IN cord-015569-vy49r1zd 232 23 a a DT cord-015569-vy49r1zd 232 24 physiological physiological JJ cord-015569-vy49r1zd 232 25 condition condition NN cord-015569-vy49r1zd 232 26 . . . cord-015569-vy49r1zd 233 1 # # $ cord-015569-vy49r1zd 233 2 21 21 CD cord-015569-vy49r1zd 233 3 Comparison comparison NN cord-015569-vy49r1zd 233 4 of of IN cord-015569-vy49r1zd 233 5 preference preference NN cord-015569-vy49r1zd 233 6 between between IN cord-015569-vy49r1zd 233 7 sucrose sucrose NN cord-015569-vy49r1zd 233 8 and and CC cord-015569-vy49r1zd 233 9 sugar sugar NN cord-015569-vy49r1zd 233 10 alcohols alcohol NNS cord-015569-vy49r1zd 233 11 in in IN cord-015569-vy49r1zd 233 12 C57BL/6 C57BL/6 NNP cord-015569-vy49r1zd 233 13 mice mouse NNS cord-015569-vy49r1zd 233 14 Yoshihisa Yoshihisa NNP cord-015569-vy49r1zd 233 15 Katagawa Katagawa NNP cord-015569-vy49r1zd 233 16 3 3 CD cord-015569-vy49r1zd 233 17 , , , cord-015569-vy49r1zd 233 18 Toshiaki Toshiaki NNP cord-015569-vy49r1zd 233 19 Yasuo Yasuo NNP cord-015569-vy49r1zd 233 20 1 1 CD cord-015569-vy49r1zd 233 21 , , , cord-015569-vy49r1zd 233 22 Keika Keika NNP cord-015569-vy49r1zd 233 23 Gen Gen NNP cord-015569-vy49r1zd 233 24 3 3 CD cord-015569-vy49r1zd 233 25 , , , cord-015569-vy49r1zd 233 26 Takashi Takashi NNP cord-015569-vy49r1zd 233 27 Yamamoto Yamamoto NNP cord-015569-vy49r1zd 233 28 2 2 CD cord-015569-vy49r1zd 233 29 and and CC cord-015569-vy49r1zd 233 30 Noritaka Noritaka NNP cord-015569-vy49r1zd 233 31 Sako Sako NNP cord-015569-vy49r1zd 233 32 1 1 CD cord-015569-vy49r1zd 233 33 1 1 CD cord-015569-vy49r1zd 233 34 Department Department NNP cord-015569-vy49r1zd 233 35 of of IN cord-015569-vy49r1zd 233 36 Oral Oral NNP cord-015569-vy49r1zd 233 37 Physiology Physiology NNP cord-015569-vy49r1zd 233 38 , , , cord-015569-vy49r1zd 233 39 Asahi Asahi NNP cord-015569-vy49r1zd 233 40 University University NNP cord-015569-vy49r1zd 233 41 School School NNP cord-015569-vy49r1zd 233 42 of of IN cord-015569-vy49r1zd 233 43 Dentistry Dentistry NNP cord-015569-vy49r1zd 233 44 , , , cord-015569-vy49r1zd 233 45 Mizuho Mizuho NNP cord-015569-vy49r1zd 233 46 501 501 CD cord-015569-vy49r1zd 233 47 - - HYPH cord-015569-vy49r1zd 233 48 0296 0296 CD cord-015569-vy49r1zd 233 49 , , , cord-015569-vy49r1zd 233 50 Japan Japan NNP cord-015569-vy49r1zd 233 51 , , , cord-015569-vy49r1zd 233 52 2 2 CD cord-015569-vy49r1zd 233 53 Department Department NNP cord-015569-vy49r1zd 233 54 of of IN cord-015569-vy49r1zd 233 55 Health Health NNP cord-015569-vy49r1zd 233 56 and and CC cord-015569-vy49r1zd 233 57 Nutrition Nutrition NNP cord-015569-vy49r1zd 233 58 , , , cord-015569-vy49r1zd 233 59 Faculty Faculty NNP cord-015569-vy49r1zd 233 60 of of IN cord-015569-vy49r1zd 233 61 Health Health NNP cord-015569-vy49r1zd 233 62 Science Science NNP cord-015569-vy49r1zd 233 63 , , , cord-015569-vy49r1zd 233 64 Kio Kio NNP cord-015569-vy49r1zd 233 65 University University NNP cord-015569-vy49r1zd 233 66 , , , cord-015569-vy49r1zd 233 67 Nara Nara NNP cord-015569-vy49r1zd 233 68 635 635 CD cord-015569-vy49r1zd 233 69 - - HYPH cord-015569-vy49r1zd 233 70 0832 0832 CD cord-015569-vy49r1zd 233 71 , , , cord-015569-vy49r1zd 233 72 Japan Japan NNP cord-015569-vy49r1zd 233 73 and and CC cord-015569-vy49r1zd 233 74 although although IN cord-015569-vy49r1zd 233 75 sorbitol sorbitol NN cord-015569-vy49r1zd 233 76 tended tend VBD cord-015569-vy49r1zd 233 77 to to TO cord-015569-vy49r1zd 233 78 be be VB cord-015569-vy49r1zd 233 79 less less RBR cord-015569-vy49r1zd 233 80 preferred prefer VBN cord-015569-vy49r1zd 233 81 compared compare VBN cord-015569-vy49r1zd 233 82 to to IN cord-015569-vy49r1zd 233 83 palatinit palatinit NNP cord-015569-vy49r1zd 233 84 . . . cord-015569-vy49r1zd 234 1 The the DT cord-015569-vy49r1zd 234 2 present present JJ cord-015569-vy49r1zd 234 3 study study NN cord-015569-vy49r1zd 234 4 suggests suggest VBZ cord-015569-vy49r1zd 234 5 that that IN cord-015569-vy49r1zd 234 6 the the DT cord-015569-vy49r1zd 234 7 sugar sugar NN cord-015569-vy49r1zd 234 8 alcohols alcohol NNS cord-015569-vy49r1zd 234 9 are be VBP cord-015569-vy49r1zd 234 10 less less RBR cord-015569-vy49r1zd 234 11 palatable palatable JJ cord-015569-vy49r1zd 234 12 than than IN cord-015569-vy49r1zd 234 13 that that DT cord-015569-vy49r1zd 234 14 to to IN cord-015569-vy49r1zd 234 15 common common JJ cord-015569-vy49r1zd 234 16 sugars sugar NNS cord-015569-vy49r1zd 234 17 , , , cord-015569-vy49r1zd 234 18 such such JJ cord-015569-vy49r1zd 234 19 as as IN cord-015569-vy49r1zd 234 20 sucrose sucrose NN cord-015569-vy49r1zd 234 21 , , , cord-015569-vy49r1zd 234 22 in in IN cord-015569-vy49r1zd 234 23 mice mouse NNS cord-015569-vy49r1zd 234 24 . . . cord-015569-vy49r1zd 235 1 # # $ cord-015569-vy49r1zd 235 2 22 22 CD cord-015569-vy49r1zd 235 3 Novel Novel NNP cord-015569-vy49r1zd 235 4 peptides peptide NNS cord-015569-vy49r1zd 235 5 , , , cord-015569-vy49r1zd 235 6 dRYamide-1 dryamide-1 NN cord-015569-vy49r1zd 235 7 , , , cord-015569-vy49r1zd 236 1 dRYamide-2 dryamide-2 JJ cord-015569-vy49r1zd 236 2 : : : cord-015569-vy49r1zd 236 3 Comparison comparison NN cord-015569-vy49r1zd 236 4 in in IN cord-015569-vy49r1zd 236 5 regulatory regulatory JJ cord-015569-vy49r1zd 236 6 effects effect NNS cord-015569-vy49r1zd 236 7 on on IN cord-015569-vy49r1zd 236 8 feeding feed VBG cord-015569-vy49r1zd 236 9 behavior behavior NN cord-015569-vy49r1zd 236 10 of of IN cord-015569-vy49r1zd 236 11 the the DT cord-015569-vy49r1zd 236 12 blowfly blowfly NNP cord-015569-vy49r1zd 236 13 Phormia Phormia NNP cord-015569-vy49r1zd 236 14 regina regina NNP cord-015569-vy49r1zd 237 1 Because because IN cord-015569-vy49r1zd 237 2 the the DT cord-015569-vy49r1zd 237 3 Drosophila Drosophila NNP cord-015569-vy49r1zd 237 4 orphan orphan NN cord-015569-vy49r1zd 237 5 receptor receptor NN cord-015569-vy49r1zd 237 6 CG5811 CG5811 NNP cord-015569-vy49r1zd 237 7 is be VBZ cord-015569-vy49r1zd 237 8 similar similar JJ cord-015569-vy49r1zd 237 9 to to IN cord-015569-vy49r1zd 237 10 the the DT cord-015569-vy49r1zd 237 11 vertebrate vertebrate JJ cord-015569-vy49r1zd 237 12 neuropeptide neuropeptide NN cord-015569-vy49r1zd 237 13 Y Y NNP cord-015569-vy49r1zd 237 14 receptor receptor NN cord-015569-vy49r1zd 237 15 , , , cord-015569-vy49r1zd 237 16 we -PRON- PRP cord-015569-vy49r1zd 237 17 screened screen VBD cord-015569-vy49r1zd 237 18 its -PRON- PRP$ cord-015569-vy49r1zd 237 19 putative putative JJ cord-015569-vy49r1zd 237 20 ligands ligand NNS cord-015569-vy49r1zd 237 21 and and CC cord-015569-vy49r1zd 237 22 purified purify VBD cord-015569-vy49r1zd 237 23 two two CD cord-015569-vy49r1zd 237 24 novel novel JJ cord-015569-vy49r1zd 237 25 peptides peptide NNS cord-015569-vy49r1zd 237 26 : : : cord-015569-vy49r1zd 237 27 dRYamide-1 dRYamide-1 NNP cord-015569-vy49r1zd 237 28 and and CC cord-015569-vy49r1zd 237 29 -2 -2 NNP cord-015569-vy49r1zd 237 30 . . . cord-015569-vy49r1zd 238 1 To to TO cord-015569-vy49r1zd 238 2 investigate investigate VB cord-015569-vy49r1zd 238 3 their -PRON- PRP$ cord-015569-vy49r1zd 238 4 function function NN cord-015569-vy49r1zd 238 5 , , , cord-015569-vy49r1zd 238 6 we -PRON- PRP cord-015569-vy49r1zd 238 7 injected inject VBD cord-015569-vy49r1zd 238 8 these these DT cord-015569-vy49r1zd 238 9 peptides peptide NNS cord-015569-vy49r1zd 238 10 into into IN cord-015569-vy49r1zd 238 11 the the DT cord-015569-vy49r1zd 238 12 thorax thorax NN cord-015569-vy49r1zd 238 13 of of IN cord-015569-vy49r1zd 238 14 the the DT cord-015569-vy49r1zd 238 15 blow blow NN cord-015569-vy49r1zd 238 16 fly fly NN cord-015569-vy49r1zd 238 17 , , , cord-015569-vy49r1zd 238 18 Phormia Phormia NNP cord-015569-vy49r1zd 238 19 regina regina NNP cord-015569-vy49r1zd 238 20 , , , cord-015569-vy49r1zd 238 21 and and CC cord-015569-vy49r1zd 238 22 observed observe VBD cord-015569-vy49r1zd 238 23 the the DT cord-015569-vy49r1zd 238 24 subsequent subsequent JJ cord-015569-vy49r1zd 238 25 changes change NNS cord-015569-vy49r1zd 238 26 in in IN cord-015569-vy49r1zd 238 27 feeding feed VBG cord-015569-vy49r1zd 238 28 behavior behavior NN cord-015569-vy49r1zd 238 29 and and CC cord-015569-vy49r1zd 238 30 taste taste VB cord-015569-vy49r1zd 238 31 sensitivity sensitivity NN cord-015569-vy49r1zd 238 32 to to IN cord-015569-vy49r1zd 238 33 sucrose sucrose NN cord-015569-vy49r1zd 238 34 . . . cord-015569-vy49r1zd 239 1 The the DT cord-015569-vy49r1zd 239 2 blow blow NN cord-015569-vy49r1zd 239 3 fly fly NN cord-015569-vy49r1zd 239 4 was be VBD cord-015569-vy49r1zd 239 5 used use VBN cord-015569-vy49r1zd 239 6 for for IN cord-015569-vy49r1zd 239 7 technical technical JJ cord-015569-vy49r1zd 239 8 reasons reason NNS cord-015569-vy49r1zd 239 9 , , , cord-015569-vy49r1zd 239 10 to to TO cord-015569-vy49r1zd 239 11 facilitate facilitate VB cord-015569-vy49r1zd 239 12 injection injection NN cord-015569-vy49r1zd 239 13 . . . cord-015569-vy49r1zd 240 1 Before before IN cord-015569-vy49r1zd 240 2 and and CC cord-015569-vy49r1zd 240 3 after after IN cord-015569-vy49r1zd 240 4 peptide peptide JJ cord-015569-vy49r1zd 240 5 injection injection NN cord-015569-vy49r1zd 240 6 , , , cord-015569-vy49r1zd 240 7 we -PRON- PRP cord-015569-vy49r1zd 240 8 measured measure VBD cord-015569-vy49r1zd 240 9 1 1 CD cord-015569-vy49r1zd 240 10 ) ) -RRB- cord-015569-vy49r1zd 241 1 the the DT cord-015569-vy49r1zd 241 2 sucrose sucrose NN cord-015569-vy49r1zd 241 3 intake intake NN cord-015569-vy49r1zd 241 4 as as IN cord-015569-vy49r1zd 241 5 an an DT cord-015569-vy49r1zd 241 6 indicator indicator NN cord-015569-vy49r1zd 241 7 of of IN cord-015569-vy49r1zd 241 8 appetite appetite NN cord-015569-vy49r1zd 241 9 , , , cord-015569-vy49r1zd 241 10 2 2 LS cord-015569-vy49r1zd 241 11 ) ) -RRB- cord-015569-vy49r1zd 241 12 the the DT cord-015569-vy49r1zd 241 13 proboscis proboscis NN cord-015569-vy49r1zd 241 14 extension extension NN cord-015569-vy49r1zd 241 15 reflex reflex NN cord-015569-vy49r1zd 241 16 ( ( -LRB- cord-015569-vy49r1zd 241 17 PER per NN cord-015569-vy49r1zd 241 18 ) ) -RRB- cord-015569-vy49r1zd 241 19 as as IN cord-015569-vy49r1zd 241 20 an an DT cord-015569-vy49r1zd 241 21 indicator indicator NN cord-015569-vy49r1zd 241 22 of of IN cord-015569-vy49r1zd 241 23 feeding feed VBG cord-015569-vy49r1zd 241 24 motivation motivation NN cord-015569-vy49r1zd 241 25 , , , cord-015569-vy49r1zd 241 26 and and CC cord-015569-vy49r1zd 241 27 3 3 LS cord-015569-vy49r1zd 241 28 ) ) -RRB- cord-015569-vy49r1zd 241 29 the the DT cord-015569-vy49r1zd 241 30 electrophysiological electrophysiological JJ cord-015569-vy49r1zd 241 31 response response NN cord-015569-vy49r1zd 241 32 of of IN cord-015569-vy49r1zd 241 33 the the DT cord-015569-vy49r1zd 241 34 labellar labellar NNP cord-015569-vy49r1zd 241 35 contact contact NN cord-015569-vy49r1zd 241 36 chemosensilla chemosensilla NNP cord-015569-vy49r1zd 241 37 to to TO cord-015569-vy49r1zd 241 38 measure measure VB cord-015569-vy49r1zd 241 39 the the DT cord-015569-vy49r1zd 241 40 magnitude magnitude NN cord-015569-vy49r1zd 241 41 of of IN cord-015569-vy49r1zd 241 42 the the DT cord-015569-vy49r1zd 241 43 gustatory gustatory JJ cord-015569-vy49r1zd 241 44 input input NN cord-015569-vy49r1zd 241 45 inducing induce VBG cord-015569-vy49r1zd 241 46 PER per NN cord-015569-vy49r1zd 241 47 . . . cord-015569-vy49r1zd 242 1 There there EX cord-015569-vy49r1zd 242 2 was be VBD cord-015569-vy49r1zd 242 3 no no DT cord-015569-vy49r1zd 242 4 significant significant JJ cord-015569-vy49r1zd 242 5 change change NN cord-015569-vy49r1zd 242 6 in in IN cord-015569-vy49r1zd 242 7 sucrose sucrose NN cord-015569-vy49r1zd 242 8 intake intake NN cord-015569-vy49r1zd 242 9 after after IN cord-015569-vy49r1zd 242 10 injection injection NN cord-015569-vy49r1zd 242 11 . . . cord-015569-vy49r1zd 243 1 Injecting inject VBG cord-015569-vy49r1zd 243 2 both both DT cord-015569-vy49r1zd 243 3 peptides peptide NNS cord-015569-vy49r1zd 243 4 depressed depress VBN cord-015569-vy49r1zd 243 5 PER per NN cord-015569-vy49r1zd 243 6 and and CC cord-015569-vy49r1zd 243 7 reduced reduce VBD cord-015569-vy49r1zd 243 8 the the DT cord-015569-vy49r1zd 243 9 percentage percentage NN cord-015569-vy49r1zd 243 10 of of IN cord-015569-vy49r1zd 243 11 flies fly NNS cord-015569-vy49r1zd 243 12 that that WDT cord-015569-vy49r1zd 243 13 performed perform VBD cord-015569-vy49r1zd 243 14 PER per NN cord-015569-vy49r1zd 243 15 . . . cord-015569-vy49r1zd 244 1 The the DT cord-015569-vy49r1zd 244 2 electrophysiological electrophysiological JJ cord-015569-vy49r1zd 244 3 response response NN cord-015569-vy49r1zd 244 4 of of IN cord-015569-vy49r1zd 244 5 the the DT cord-015569-vy49r1zd 244 6 labellar labellar NNP cord-015569-vy49r1zd 244 7 taste taste VBP cord-015569-vy49r1zd 244 8 sensillum sensillum NN cord-015569-vy49r1zd 244 9 to to IN cord-015569-vy49r1zd 244 10 sucrose sucrose NN cord-015569-vy49r1zd 244 11 seemed seem VBD cord-015569-vy49r1zd 244 12 to to TO cord-015569-vy49r1zd 244 13 decrease decrease VB cord-015569-vy49r1zd 244 14 after after IN cord-015569-vy49r1zd 244 15 injecting inject VBG cord-015569-vy49r1zd 244 16 dRYamide-1 dryamide-1 NN cord-015569-vy49r1zd 244 17 , , , cord-015569-vy49r1zd 244 18 but but CC cord-015569-vy49r1zd 244 19 not not RB cord-015569-vy49r1zd 244 20 dRYamide-2 dryamide-2 JJ cord-015569-vy49r1zd 244 21 . . . cord-015569-vy49r1zd 245 1 Therefore therefore RB cord-015569-vy49r1zd 245 2 , , , cord-015569-vy49r1zd 245 3 once once RB cord-015569-vy49r1zd 245 4 feeding feeding NN cord-015569-vy49r1zd 245 5 starts start VBZ cord-015569-vy49r1zd 245 6 , , , cord-015569-vy49r1zd 245 7 these these DT cord-015569-vy49r1zd 245 8 peptides peptide NNS cord-015569-vy49r1zd 245 9 might may MD cord-015569-vy49r1zd 245 10 not not RB cord-015569-vy49r1zd 245 11 limit limit VB cord-015569-vy49r1zd 245 12 the the DT cord-015569-vy49r1zd 245 13 food food NN cord-015569-vy49r1zd 245 14 intake intake NN cord-015569-vy49r1zd 245 15 of of IN cord-015569-vy49r1zd 245 16 the the DT cord-015569-vy49r1zd 245 17 fly fly NN cord-015569-vy49r1zd 245 18 . . . cord-015569-vy49r1zd 246 1 Nevertheless nevertheless RB cord-015569-vy49r1zd 246 2 , , , cord-015569-vy49r1zd 246 3 the the DT cord-015569-vy49r1zd 246 4 results result NNS cord-015569-vy49r1zd 246 5 of of IN cord-015569-vy49r1zd 246 6 the the DT cord-015569-vy49r1zd 246 7 PER per NN cord-015569-vy49r1zd 246 8 test test NN cord-015569-vy49r1zd 246 9 suggest suggest VBP cord-015569-vy49r1zd 246 10 that that IN cord-015569-vy49r1zd 246 11 these these DT cord-015569-vy49r1zd 246 12 peptides peptide NNS cord-015569-vy49r1zd 246 13 contribute contribute VBP cord-015569-vy49r1zd 246 14 to to IN cord-015569-vy49r1zd 246 15 feeding feed VBG cord-015569-vy49r1zd 246 16 initiation initiation NN cord-015569-vy49r1zd 246 17 . . . cord-015569-vy49r1zd 247 1 Together together RB cord-015569-vy49r1zd 247 2 with with IN cord-015569-vy49r1zd 247 3 other other JJ cord-015569-vy49r1zd 247 4 peptides peptide NNS cord-015569-vy49r1zd 247 5 that that WDT cord-015569-vy49r1zd 247 6 restrict restrict VBP cord-015569-vy49r1zd 247 7 food food NN cord-015569-vy49r1zd 247 8 intake intake NN cord-015569-vy49r1zd 247 9 , , , cord-015569-vy49r1zd 247 10 dRYamide-1 dryamide-1 JJ cord-015569-vy49r1zd 247 11 and and CC cord-015569-vy49r1zd 247 12 -2 -2 NN cord-015569-vy49r1zd 247 13 might may MD cord-015569-vy49r1zd 247 14 contribute contribute VB cord-015569-vy49r1zd 247 15 to to IN cord-015569-vy49r1zd 247 16 the the DT cord-015569-vy49r1zd 247 17 overall overall JJ cord-015569-vy49r1zd 247 18 regulation regulation NN cord-015569-vy49r1zd 247 19 of of IN cord-015569-vy49r1zd 247 20 feeding feed VBG cord-015569-vy49r1zd 247 21 behavior behavior NN cord-015569-vy49r1zd 247 22 in in IN cord-015569-vy49r1zd 247 23 Phormia Phormia NNP cord-015569-vy49r1zd 247 24 regina regina NNP cord-015569-vy49r1zd 247 25 . . . cord-015569-vy49r1zd 248 1 # # $ cord-015569-vy49r1zd 248 2 23 23 CD cord-015569-vy49r1zd 248 3 Stand stand VB cord-015569-vy49r1zd 248 4 off off RP cord-015569-vy49r1zd 248 5 effect effect NN cord-015569-vy49r1zd 248 6 between between IN cord-015569-vy49r1zd 248 7 the the DT cord-015569-vy49r1zd 248 8 noble noble JJ cord-015569-vy49r1zd 248 9 bioactive bioactive JJ cord-015569-vy49r1zd 248 10 peptide peptide NN cord-015569-vy49r1zd 248 11 and and CC cord-015569-vy49r1zd 248 12 appetitive appetitive JJ cord-015569-vy49r1zd 248 13 odor odor NN cord-015569-vy49r1zd 248 14 on on IN cord-015569-vy49r1zd 248 15 feeding feed VBG cord-015569-vy49r1zd 248 16 behavior behavior NN cord-015569-vy49r1zd 248 17 in in IN cord-015569-vy49r1zd 248 18 blowfly blowfly NNP cord-015569-vy49r1zd 249 1 We -PRON- PRP cord-015569-vy49r1zd 249 2 compared compare VBD cord-015569-vy49r1zd 249 3 the the DT cord-015569-vy49r1zd 249 4 behavioral behavioral JJ cord-015569-vy49r1zd 249 5 effects effect NNS cord-015569-vy49r1zd 249 6 of of IN cord-015569-vy49r1zd 249 7 feeding feed VBG cord-015569-vy49r1zd 249 8 suppression suppression NN cord-015569-vy49r1zd 249 9 by by IN cord-015569-vy49r1zd 249 10 the the DT cord-015569-vy49r1zd 249 11 two two CD cord-015569-vy49r1zd 249 12 kinds kind NNS cord-015569-vy49r1zd 249 13 of of IN cord-015569-vy49r1zd 249 14 new new JJ cord-015569-vy49r1zd 249 15 peptides peptide NNS cord-015569-vy49r1zd 249 16 ( ( -LRB- cord-015569-vy49r1zd 249 17 dRYamide-1 dRYamide-1 NNP cord-015569-vy49r1zd 249 18 , , , cord-015569-vy49r1zd 249 19 2 2 CD cord-015569-vy49r1zd 249 20 ) ) -RRB- cord-015569-vy49r1zd 249 21 in in IN cord-015569-vy49r1zd 249 22 blowfly blowfly NNP cord-015569-vy49r1zd 249 23 . . . cord-015569-vy49r1zd 250 1 Both both DT cord-015569-vy49r1zd 250 2 of of IN cord-015569-vy49r1zd 250 3 gustatory gustatory JJ cord-015569-vy49r1zd 250 4 and and CC cord-015569-vy49r1zd 250 5 olfactory olfactory JJ cord-015569-vy49r1zd 250 6 systems system NNS cord-015569-vy49r1zd 250 7 are be VBP cord-015569-vy49r1zd 250 8 required require VBN cord-015569-vy49r1zd 250 9 to to TO cord-015569-vy49r1zd 250 10 elicit elicit VB cord-015569-vy49r1zd 250 11 appropriate appropriate JJ cord-015569-vy49r1zd 250 12 motor motor NN cord-015569-vy49r1zd 250 13 pattern pattern NN cord-015569-vy49r1zd 250 14 in in IN cord-015569-vy49r1zd 250 15 feeding feed VBG cord-015569-vy49r1zd 250 16 behavior behavior NN cord-015569-vy49r1zd 250 17 . . . cord-015569-vy49r1zd 251 1 Feeding feed VBG cord-015569-vy49r1zd 251 2 behavior behavior NN cord-015569-vy49r1zd 251 3 was be VBD cord-015569-vy49r1zd 251 4 also also RB cord-015569-vy49r1zd 251 5 controlled control VBN cord-015569-vy49r1zd 251 6 by by IN cord-015569-vy49r1zd 251 7 internal internal JJ cord-015569-vy49r1zd 251 8 condition condition NN cord-015569-vy49r1zd 251 9 based base VBN cord-015569-vy49r1zd 251 10 on on IN cord-015569-vy49r1zd 251 11 many many JJ cord-015569-vy49r1zd 251 12 bioactive bioactive JJ cord-015569-vy49r1zd 251 13 peptides peptide NNS cord-015569-vy49r1zd 251 14 . . . cord-015569-vy49r1zd 252 1 Proboscis proboscis NN cord-015569-vy49r1zd 252 2 extension extension NN cord-015569-vy49r1zd 252 3 response response NN cord-015569-vy49r1zd 252 4 ( ( -LRB- cord-015569-vy49r1zd 252 5 PER per NN cord-015569-vy49r1zd 252 6 ) ) -RRB- cord-015569-vy49r1zd 252 7 is be VBZ cord-015569-vy49r1zd 252 8 indicator indicator NN cord-015569-vy49r1zd 252 9 of of IN cord-015569-vy49r1zd 252 10 feeding feed VBG cord-015569-vy49r1zd 252 11 behavior behavior NN cord-015569-vy49r1zd 252 12 that that WDT cord-015569-vy49r1zd 252 13 is be VBZ cord-015569-vy49r1zd 252 14 generally generally RB cord-015569-vy49r1zd 252 15 controlled control VBN cord-015569-vy49r1zd 252 16 by by IN cord-015569-vy49r1zd 252 17 the the DT cord-015569-vy49r1zd 252 18 chemical chemical JJ cord-015569-vy49r1zd 252 19 cues cue NNS cord-015569-vy49r1zd 252 20 from from IN cord-015569-vy49r1zd 252 21 the the DT cord-015569-vy49r1zd 252 22 maxillary maxillary JJ cord-015569-vy49r1zd 252 23 palps palp NNS cord-015569-vy49r1zd 252 24 . . . cord-015569-vy49r1zd 253 1 The the DT cord-015569-vy49r1zd 253 2 behavioral behavioral JJ cord-015569-vy49r1zd 253 3 experiment experiment NN cord-015569-vy49r1zd 253 4 showed show VBD cord-015569-vy49r1zd 253 5 that that IN cord-015569-vy49r1zd 253 6 they -PRON- PRP cord-015569-vy49r1zd 253 7 detect detect VBP cord-015569-vy49r1zd 253 8 palatable palatable JJ cord-015569-vy49r1zd 253 9 chemical chemical NN cord-015569-vy49r1zd 253 10 signals signal NNS cord-015569-vy49r1zd 253 11 increasing increase VBG cord-015569-vy49r1zd 253 12 their -PRON- PRP$ cord-015569-vy49r1zd 253 13 appetite appetite NN cord-015569-vy49r1zd 253 14 in in IN cord-015569-vy49r1zd 253 15 blowfly blowfly NNP cord-015569-vy49r1zd 253 16 , , , cord-015569-vy49r1zd 253 17 Phormia Phormia NNP cord-015569-vy49r1zd 253 18 regina regina NNP cord-015569-vy49r1zd 253 19 . . . cord-015569-vy49r1zd 254 1 Phormia Phormia NNP cord-015569-vy49r1zd 254 2 usually usually RB cord-015569-vy49r1zd 254 3 have have VBP cord-015569-vy49r1zd 254 4 detected detect VBN cord-015569-vy49r1zd 254 5 the the DT cord-015569-vy49r1zd 254 6 appetite appetite NN cord-015569-vy49r1zd 254 7 odor odor NN cord-015569-vy49r1zd 254 8 like like IN cord-015569-vy49r1zd 254 9 mushroom mushroom NN cord-015569-vy49r1zd 254 10 ( ( -LRB- cord-015569-vy49r1zd 254 11 1-octen-3-ol 1-octen-3-ol CD cord-015569-vy49r1zd 254 12 ) ) -RRB- cord-015569-vy49r1zd 254 13 by by IN cord-015569-vy49r1zd 254 14 maxillary maxillary JJ cord-015569-vy49r1zd 254 15 palps palp NNS cord-015569-vy49r1zd 254 16 . . . cord-015569-vy49r1zd 255 1 However however RB cord-015569-vy49r1zd 255 2 , , , cord-015569-vy49r1zd 255 3 some some DT cord-015569-vy49r1zd 255 4 kinds kind NNS cord-015569-vy49r1zd 255 5 of of IN cord-015569-vy49r1zd 255 6 newly newly RB cord-015569-vy49r1zd 255 7 found find VBN cord-015569-vy49r1zd 255 8 peptide peptide JJ cord-015569-vy49r1zd 255 9 have have VBP cord-015569-vy49r1zd 255 10 an an DT cord-015569-vy49r1zd 255 11 effect effect NN cord-015569-vy49r1zd 255 12 on on IN cord-015569-vy49r1zd 255 13 feeding feed VBG cord-015569-vy49r1zd 255 14 behavior behavior NN cord-015569-vy49r1zd 255 15 . . . cord-015569-vy49r1zd 256 1 Therefore therefore RB cord-015569-vy49r1zd 256 2 , , , cord-015569-vy49r1zd 256 3 we -PRON- PRP cord-015569-vy49r1zd 256 4 compared compare VBD cord-015569-vy49r1zd 256 5 the the DT cord-015569-vy49r1zd 256 6 effect effect NN cord-015569-vy49r1zd 256 7 of of IN cord-015569-vy49r1zd 256 8 two two CD cord-015569-vy49r1zd 256 9 kinds kind NNS cord-015569-vy49r1zd 256 10 of of IN cord-015569-vy49r1zd 256 11 newly newly RB cord-015569-vy49r1zd 256 12 found find VBN cord-015569-vy49r1zd 256 13 peptides peptide NNS cord-015569-vy49r1zd 256 14 in in IN cord-015569-vy49r1zd 256 15 drosophila drosophila NN cord-015569-vy49r1zd 256 16 . . . cord-015569-vy49r1zd 257 1 First first RB cord-015569-vy49r1zd 257 2 , , , cord-015569-vy49r1zd 257 3 we -PRON- PRP cord-015569-vy49r1zd 257 4 test test VBP cord-015569-vy49r1zd 257 5 whether whether IN cord-015569-vy49r1zd 257 6 they -PRON- PRP cord-015569-vy49r1zd 257 7 affect affect VBP cord-015569-vy49r1zd 257 8 feeding feed VBG cord-015569-vy49r1zd 257 9 behavior behavior NN cord-015569-vy49r1zd 257 10 by by IN cord-015569-vy49r1zd 257 11 the the DT cord-015569-vy49r1zd 257 12 amount amount NN cord-015569-vy49r1zd 257 13 of of IN cord-015569-vy49r1zd 257 14 sucrose sucrose NN cord-015569-vy49r1zd 257 15 intake intake NN cord-015569-vy49r1zd 257 16 . . . cord-015569-vy49r1zd 258 1 After after IN cord-015569-vy49r1zd 258 2 injection injection NN cord-015569-vy49r1zd 258 3 of of IN cord-015569-vy49r1zd 258 4 one one CD cord-015569-vy49r1zd 258 5 kind kind NN cord-015569-vy49r1zd 258 6 of of IN cord-015569-vy49r1zd 258 7 peptide peptide NN cord-015569-vy49r1zd 258 8 , , , cord-015569-vy49r1zd 258 9 food food NN cord-015569-vy49r1zd 258 10 intake intake NN cord-015569-vy49r1zd 258 11 amount amount NN cord-015569-vy49r1zd 258 12 was be VBD cord-015569-vy49r1zd 258 13 obviously obviously RB cord-015569-vy49r1zd 258 14 increased increase VBN cord-015569-vy49r1zd 258 15 . . . cord-015569-vy49r1zd 259 1 In in IN cord-015569-vy49r1zd 259 2 the the DT cord-015569-vy49r1zd 259 3 next next JJ cord-015569-vy49r1zd 259 4 step step NN cord-015569-vy49r1zd 259 5 , , , cord-015569-vy49r1zd 259 6 we -PRON- PRP cord-015569-vy49r1zd 259 7 investigated investigate VBD cord-015569-vy49r1zd 259 8 the the DT cord-015569-vy49r1zd 259 9 odor odor NN cord-015569-vy49r1zd 259 10 of of IN cord-015569-vy49r1zd 259 11 1octen-3-ol 1octen-3-ol CD cord-015569-vy49r1zd 259 12 by by IN cord-015569-vy49r1zd 259 13 maxillary maxillary JJ cord-015569-vy49r1zd 259 14 palps palps NNPS cord-015569-vy49r1zd 259 15 did do VBD cord-015569-vy49r1zd 259 16 not not RB cord-015569-vy49r1zd 259 17 work work VB cord-015569-vy49r1zd 259 18 as as IN cord-015569-vy49r1zd 259 19 appetitive appetitive JJ cord-015569-vy49r1zd 259 20 odor odor NN cord-015569-vy49r1zd 259 21 when when WRB cord-015569-vy49r1zd 259 22 they -PRON- PRP cord-015569-vy49r1zd 259 23 are be VBP cord-015569-vy49r1zd 259 24 starved starve VBN cord-015569-vy49r1zd 259 25 sufficiently sufficiently RB cord-015569-vy49r1zd 259 26 in in IN cord-015569-vy49r1zd 259 27 behavioral behavioral JJ cord-015569-vy49r1zd 259 28 experiments experiment NNS cord-015569-vy49r1zd 259 29 . . . cord-015569-vy49r1zd 260 1 The the DT cord-015569-vy49r1zd 260 2 results result NNS cord-015569-vy49r1zd 260 3 showed show VBD cord-015569-vy49r1zd 260 4 that that IN cord-015569-vy49r1zd 260 5 these these DT cord-015569-vy49r1zd 260 6 peptides peptide NNS cord-015569-vy49r1zd 260 7 work work VBP cord-015569-vy49r1zd 260 8 as as IN cord-015569-vy49r1zd 260 9 the the DT cord-015569-vy49r1zd 260 10 appetitesuppressant appetitesuppressant JJ cord-015569-vy49r1zd 260 11 in in IN cord-015569-vy49r1zd 260 12 blowfly blowfly NNP cord-015569-vy49r1zd 260 13 feeding feeding NN cord-015569-vy49r1zd 260 14 behavior behavior NN cord-015569-vy49r1zd 260 15 , , , cord-015569-vy49r1zd 260 16 and and CC cord-015569-vy49r1zd 260 17 it -PRON- PRP cord-015569-vy49r1zd 260 18 did do VBD cord-015569-vy49r1zd 260 19 worked work VBD cord-015569-vy49r1zd 260 20 as as IN cord-015569-vy49r1zd 260 21 counteractant counteractant NN cord-015569-vy49r1zd 260 22 to to IN cord-015569-vy49r1zd 260 23 odor odor NN cord-015569-vy49r1zd 260 24 stimulation stimulation NN cord-015569-vy49r1zd 260 25 . . . cord-015569-vy49r1zd 261 1 Sodium sodium NN cord-015569-vy49r1zd 261 2 - - HYPH cord-015569-vy49r1zd 261 3 deficient deficient JJ cord-015569-vy49r1zd 261 4 animals animal NNS cord-015569-vy49r1zd 261 5 ingest ingest VBP cord-015569-vy49r1zd 261 6 sodium sodium NN cord-015569-vy49r1zd 261 7 chloride chloride NN cord-015569-vy49r1zd 261 8 at at IN cord-015569-vy49r1zd 261 9 concentrations concentration NNS cord-015569-vy49r1zd 261 10 normally normally RB cord-015569-vy49r1zd 261 11 rejected reject VBD cord-015569-vy49r1zd 261 12 , , , cord-015569-vy49r1zd 261 13 and and CC cord-015569-vy49r1zd 261 14 this this DT cord-015569-vy49r1zd 261 15 motivated motivated JJ cord-015569-vy49r1zd 261 16 behavioral behavioral JJ cord-015569-vy49r1zd 261 17 state state NN cord-015569-vy49r1zd 261 18 is be VBZ cord-015569-vy49r1zd 261 19 known know VBN cord-015569-vy49r1zd 261 20 as as IN cord-015569-vy49r1zd 261 21 sodium sodium NN cord-015569-vy49r1zd 261 22 appetite appetite NN cord-015569-vy49r1zd 261 23 . . . cord-015569-vy49r1zd 262 1 For for IN cord-015569-vy49r1zd 262 2 neural neural JJ cord-015569-vy49r1zd 262 3 mechanisms mechanism NNS cord-015569-vy49r1zd 262 4 of of IN cord-015569-vy49r1zd 262 5 sodium sodium NN cord-015569-vy49r1zd 262 6 appetite appetite NN cord-015569-vy49r1zd 262 7 , , , cord-015569-vy49r1zd 262 8 there there EX cord-015569-vy49r1zd 262 9 is be VBZ cord-015569-vy49r1zd 262 10 a a DT cord-015569-vy49r1zd 262 11 line line NN cord-015569-vy49r1zd 262 12 of of IN cord-015569-vy49r1zd 262 13 electrophysiological electrophysiological JJ cord-015569-vy49r1zd 262 14 evidence evidence NN cord-015569-vy49r1zd 262 15 in in IN cord-015569-vy49r1zd 262 16 rats rat NNS cord-015569-vy49r1zd 262 17 , , , cord-015569-vy49r1zd 262 18 whereas whereas IN cord-015569-vy49r1zd 262 19 there there EX cord-015569-vy49r1zd 262 20 is be VBZ cord-015569-vy49r1zd 262 21 less less JJR cord-015569-vy49r1zd 262 22 evidence evidence NN cord-015569-vy49r1zd 262 23 in in IN cord-015569-vy49r1zd 262 24 mice mouse NNS cord-015569-vy49r1zd 262 25 . . . cord-015569-vy49r1zd 263 1 In in IN cord-015569-vy49r1zd 263 2 order order NN cord-015569-vy49r1zd 263 3 to to TO cord-015569-vy49r1zd 263 4 develop develop VB cord-015569-vy49r1zd 263 5 a a DT cord-015569-vy49r1zd 263 6 model model NN cord-015569-vy49r1zd 263 7 for for IN cord-015569-vy49r1zd 263 8 sodium sodium NN cord-015569-vy49r1zd 263 9 appetite appetite NN cord-015569-vy49r1zd 263 10 in in IN cord-015569-vy49r1zd 263 11 mice mouse NNS cord-015569-vy49r1zd 263 12 , , , cord-015569-vy49r1zd 263 13 we -PRON- PRP cord-015569-vy49r1zd 263 14 examined examine VBD cord-015569-vy49r1zd 263 15 the the DT cord-015569-vy49r1zd 263 16 effects effect NNS cord-015569-vy49r1zd 263 17 of of IN cord-015569-vy49r1zd 263 18 repeated repeat VBN cord-015569-vy49r1zd 263 19 sodium sodium NN cord-015569-vy49r1zd 263 20 depletion depletion NN cord-015569-vy49r1zd 263 21 on on IN cord-015569-vy49r1zd 263 22 salt salt NN cord-015569-vy49r1zd 263 23 intakes intake NNS cord-015569-vy49r1zd 263 24 in in IN cord-015569-vy49r1zd 263 25 C57BL/6J C57BL/6J NNP cord-015569-vy49r1zd 263 26 mice mouse NNS cord-015569-vy49r1zd 263 27 . . . cord-015569-vy49r1zd 264 1 Adult adult JJ cord-015569-vy49r1zd 264 2 male male NN cord-015569-vy49r1zd 264 3 C57BL/6J C57BL/6J NNP cord-015569-vy49r1zd 264 4 mice mouse NNS cord-015569-vy49r1zd 264 5 ( ( -LRB- cord-015569-vy49r1zd 264 6 n=5 n=5 RB cord-015569-vy49r1zd 264 7 , , , cord-015569-vy49r1zd 264 8 8 8 CD cord-015569-vy49r1zd 264 9 weeks week NNS cord-015569-vy49r1zd 264 10 , , , cord-015569-vy49r1zd 264 11 21 21 CD cord-015569-vy49r1zd 264 12 - - SYM cord-015569-vy49r1zd 264 13 26 26 CD cord-015569-vy49r1zd 264 14 g g NN cord-015569-vy49r1zd 264 15 at at IN cord-015569-vy49r1zd 264 16 the the DT cord-015569-vy49r1zd 264 17 beginning beginning NN cord-015569-vy49r1zd 264 18 of of IN cord-015569-vy49r1zd 264 19 the the DT cord-015569-vy49r1zd 264 20 experiment experiment NN cord-015569-vy49r1zd 264 21 ) ) -RRB- cord-015569-vy49r1zd 264 22 were be VBD cord-015569-vy49r1zd 264 23 used use VBN cord-015569-vy49r1zd 264 24 ; ; : cord-015569-vy49r1zd 264 25 each each DT cord-015569-vy49r1zd 264 26 animal animal NN cord-015569-vy49r1zd 264 27 was be VBD cord-015569-vy49r1zd 264 28 housed house VBN cord-015569-vy49r1zd 264 29 individually individually RB cord-015569-vy49r1zd 264 30 in in IN cord-015569-vy49r1zd 264 31 a a DT cord-015569-vy49r1zd 264 32 metabolism metabolism NN cord-015569-vy49r1zd 264 33 cage cage NN cord-015569-vy49r1zd 264 34 during during IN cord-015569-vy49r1zd 264 35 the the DT cord-015569-vy49r1zd 264 36 experiment experiment NN cord-015569-vy49r1zd 264 37 . . . cord-015569-vy49r1zd 265 1 A a DT cord-015569-vy49r1zd 265 2 combination combination NN cord-015569-vy49r1zd 265 3 of of IN cord-015569-vy49r1zd 265 4 furosemide furosemide NN cord-015569-vy49r1zd 265 5 injection injection NN cord-015569-vy49r1zd 265 6 with with IN cord-015569-vy49r1zd 265 7 sodium sodium NN cord-015569-vy49r1zd 265 8 - - HYPH cord-015569-vy49r1zd 265 9 deficient deficient JJ cord-015569-vy49r1zd 265 10 diet diet NN cord-015569-vy49r1zd 265 11 was be VBD cord-015569-vy49r1zd 265 12 used use VBN cord-015569-vy49r1zd 265 13 to to TO cord-015569-vy49r1zd 265 14 induce induce VB cord-015569-vy49r1zd 265 15 acute acute JJ cord-015569-vy49r1zd 265 16 sodium sodium NN cord-015569-vy49r1zd 265 17 deficiency deficiency NN cord-015569-vy49r1zd 265 18 . . . cord-015569-vy49r1zd 266 1 In in IN cord-015569-vy49r1zd 266 2 3 3 CD cord-015569-vy49r1zd 266 3 of of IN cord-015569-vy49r1zd 266 4 the the DT cord-015569-vy49r1zd 266 5 5 5 CD cord-015569-vy49r1zd 266 6 mice mouse NNS cord-015569-vy49r1zd 266 7 , , , cord-015569-vy49r1zd 266 8 furosemide furosemide NN cord-015569-vy49r1zd 266 9 was be VBD cord-015569-vy49r1zd 266 10 injected inject VBN cord-015569-vy49r1zd 266 11 in in IN cord-015569-vy49r1zd 266 12 the the DT cord-015569-vy49r1zd 266 13 1st 1st JJ cord-015569-vy49r1zd 266 14 week week NN cord-015569-vy49r1zd 266 15 and and CC cord-015569-vy49r1zd 266 16 saline saline NN cord-015569-vy49r1zd 266 17 was be VBD cord-015569-vy49r1zd 266 18 injected inject VBN cord-015569-vy49r1zd 266 19 in in IN cord-015569-vy49r1zd 266 20 the the DT cord-015569-vy49r1zd 266 21 2nd 2nd JJ cord-015569-vy49r1zd 266 22 week week NN cord-015569-vy49r1zd 266 23 . . . cord-015569-vy49r1zd 267 1 In in IN cord-015569-vy49r1zd 267 2 the the DT cord-015569-vy49r1zd 267 3 remaining remain VBG cord-015569-vy49r1zd 267 4 2 2 CD cord-015569-vy49r1zd 267 5 mice mouse NNS cord-015569-vy49r1zd 267 6 , , , cord-015569-vy49r1zd 267 7 the the DT cord-015569-vy49r1zd 267 8 injection injection NN cord-015569-vy49r1zd 267 9 order order NN cord-015569-vy49r1zd 267 10 was be VBD cord-015569-vy49r1zd 267 11 reversed reverse VBN cord-015569-vy49r1zd 267 12 . . . cord-015569-vy49r1zd 268 1 This this DT cord-015569-vy49r1zd 268 2 pattern pattern NN cord-015569-vy49r1zd 268 3 was be VBD cord-015569-vy49r1zd 268 4 repeated repeat VBN cord-015569-vy49r1zd 268 5 4 4 CD cord-015569-vy49r1zd 268 6 times time NNS cord-015569-vy49r1zd 268 7 over over IN cord-015569-vy49r1zd 268 8 2 2 CD cord-015569-vy49r1zd 268 9 months month NNS cord-015569-vy49r1zd 268 10 . . . cord-015569-vy49r1zd 269 1 After after IN cord-015569-vy49r1zd 269 2 24 24 CD cord-015569-vy49r1zd 269 3 hours hour NNS cord-015569-vy49r1zd 269 4 following follow VBG cord-015569-vy49r1zd 269 5 the the DT cord-015569-vy49r1zd 269 6 injection injection NN cord-015569-vy49r1zd 269 7 , , , cord-015569-vy49r1zd 269 8 intakes intake NNS cord-015569-vy49r1zd 269 9 of of IN cord-015569-vy49r1zd 269 10 0.3 0.3 CD cord-015569-vy49r1zd 269 11 M M NNP cord-015569-vy49r1zd 269 12 NaCl nacl NN cord-015569-vy49r1zd 269 13 and and CC cord-015569-vy49r1zd 269 14 distilled distilled JJ cord-015569-vy49r1zd 269 15 water water NN cord-015569-vy49r1zd 269 16 were be VBD cord-015569-vy49r1zd 269 17 measured measure VBN cord-015569-vy49r1zd 269 18 . . . cord-015569-vy49r1zd 270 1 The the DT cord-015569-vy49r1zd 270 2 furosemide furosemide NN cord-015569-vy49r1zd 270 3 injection injection NN cord-015569-vy49r1zd 270 4 shortened shorten VBD cord-015569-vy49r1zd 270 5 the the DT cord-015569-vy49r1zd 270 6 latency latency NN cord-015569-vy49r1zd 270 7 of of IN cord-015569-vy49r1zd 270 8 , , , cord-015569-vy49r1zd 270 9 and and CC cord-015569-vy49r1zd 270 10 increased increase VBD cord-015569-vy49r1zd 270 11 the the DT cord-015569-vy49r1zd 270 12 amount amount NN cord-015569-vy49r1zd 270 13 of of IN cord-015569-vy49r1zd 270 14 , , , cord-015569-vy49r1zd 270 15 0.3 0.3 CD cord-015569-vy49r1zd 270 16 M m NN cord-015569-vy49r1zd 270 17 NaCl nacl NN cord-015569-vy49r1zd 270 18 intake intake NN cord-015569-vy49r1zd 270 19 . . . cord-015569-vy49r1zd 271 1 Furthermore furthermore RB cord-015569-vy49r1zd 271 2 , , , cord-015569-vy49r1zd 271 3 the the DT cord-015569-vy49r1zd 271 4 increase increase NN cord-015569-vy49r1zd 271 5 in in IN cord-015569-vy49r1zd 271 6 0.3 0.3 CD cord-015569-vy49r1zd 271 7 M m NN cord-015569-vy49r1zd 271 8 NaCl nacl NN cord-015569-vy49r1zd 271 9 intake intake NN cord-015569-vy49r1zd 271 10 was be VBD cord-015569-vy49r1zd 271 11 tended tend VBN cord-015569-vy49r1zd 271 12 to to TO cord-015569-vy49r1zd 271 13 be be VB cord-015569-vy49r1zd 271 14 enhanced enhance VBN cord-015569-vy49r1zd 271 15 at at IN cord-015569-vy49r1zd 271 16 later later JJ cord-015569-vy49r1zd 271 17 furosemide furosemide NN cord-015569-vy49r1zd 271 18 injections injection NNS cord-015569-vy49r1zd 271 19 . . . cord-015569-vy49r1zd 272 1 Both both DT cord-015569-vy49r1zd 272 2 urine urine NN cord-015569-vy49r1zd 272 3 volume volume NN cord-015569-vy49r1zd 272 4 and and CC cord-015569-vy49r1zd 272 5 24-h 24-h JJ cord-015569-vy49r1zd 272 6 urinary urinary JJ cord-015569-vy49r1zd 272 7 sodium sodium NN cord-015569-vy49r1zd 272 8 excretion excretion NN cord-015569-vy49r1zd 272 9 were be VBD cord-015569-vy49r1zd 272 10 greater great JJR cord-015569-vy49r1zd 272 11 after after IN cord-015569-vy49r1zd 272 12 the the DT cord-015569-vy49r1zd 272 13 furosemide furosemide NN cord-015569-vy49r1zd 272 14 injection injection NN cord-015569-vy49r1zd 272 15 than than IN cord-015569-vy49r1zd 272 16 after after IN cord-015569-vy49r1zd 272 17 the the DT cord-015569-vy49r1zd 272 18 saline saline NN cord-015569-vy49r1zd 272 19 injection injection NN cord-015569-vy49r1zd 272 20 , , , cord-015569-vy49r1zd 272 21 but but CC cord-015569-vy49r1zd 272 22 there there EX cord-015569-vy49r1zd 272 23 were be VBD cord-015569-vy49r1zd 272 24 no no DT cord-015569-vy49r1zd 272 25 significant significant JJ cord-015569-vy49r1zd 272 26 differences difference NNS cord-015569-vy49r1zd 272 27 of of IN cord-015569-vy49r1zd 272 28 these these DT cord-015569-vy49r1zd 272 29 measures measure NNS cord-015569-vy49r1zd 272 30 across across IN cord-015569-vy49r1zd 272 31 repeated repeat VBN cord-015569-vy49r1zd 272 32 depletions depletion NNS cord-015569-vy49r1zd 272 33 . . . cord-015569-vy49r1zd 273 1 These these DT cord-015569-vy49r1zd 273 2 results result NNS cord-015569-vy49r1zd 273 3 show show VBP cord-015569-vy49r1zd 273 4 that that IN cord-015569-vy49r1zd 273 5 present present JJ cord-015569-vy49r1zd 273 6 procedure procedure NN cord-015569-vy49r1zd 273 7 reliably reliably RB cord-015569-vy49r1zd 273 8 elicits elicit VBZ cord-015569-vy49r1zd 273 9 sodium sodium NN cord-015569-vy49r1zd 273 10 appetite appetite NN cord-015569-vy49r1zd 273 11 in in IN cord-015569-vy49r1zd 273 12 C57BL/ C57BL/ NNP cord-015569-vy49r1zd 273 13 6J 6j CD cord-015569-vy49r1zd 273 14 mice mouse NNS cord-015569-vy49r1zd 273 15 , , , cord-015569-vy49r1zd 273 16 suggesting suggest VBG cord-015569-vy49r1zd 273 17 that that IN cord-015569-vy49r1zd 273 18 this this DT cord-015569-vy49r1zd 273 19 is be VBZ cord-015569-vy49r1zd 273 20 a a DT cord-015569-vy49r1zd 273 21 suitable suitable JJ cord-015569-vy49r1zd 273 22 experimental experimental JJ cord-015569-vy49r1zd 273 23 model model NN cord-015569-vy49r1zd 273 24 of of IN cord-015569-vy49r1zd 273 25 sodium sodium NN cord-015569-vy49r1zd 273 26 appetite appetite NN cord-015569-vy49r1zd 273 27 in in IN cord-015569-vy49r1zd 273 28 mice mouse NNS cord-015569-vy49r1zd 273 29 . . . cord-015569-vy49r1zd 274 1 The the DT cord-015569-vy49r1zd 274 2 sensations sensation NNS cord-015569-vy49r1zd 274 3 of of IN cord-015569-vy49r1zd 274 4 taste taste NN cord-015569-vy49r1zd 274 5 and and CC cord-015569-vy49r1zd 274 6 smell smell NN cord-015569-vy49r1zd 274 7 are be VBP cord-015569-vy49r1zd 274 8 the the DT cord-015569-vy49r1zd 274 9 important important JJ cord-015569-vy49r1zd 274 10 determinants determinant NNS cord-015569-vy49r1zd 274 11 guiding guide VBG cord-015569-vy49r1zd 274 12 preference preference NN cord-015569-vy49r1zd 274 13 for for IN cord-015569-vy49r1zd 274 14 foods food NNS cord-015569-vy49r1zd 274 15 and and CC cord-015569-vy49r1zd 274 16 fluids fluid NNS cord-015569-vy49r1zd 274 17 . . . cord-015569-vy49r1zd 275 1 The the DT cord-015569-vy49r1zd 275 2 dried dry VBN cord-015569-vy49r1zd 275 3 - - HYPH cord-015569-vy49r1zd 275 4 bonito bonito FW cord-015569-vy49r1zd 275 5 dashi dashi NN cord-015569-vy49r1zd 275 6 is be VBZ cord-015569-vy49r1zd 275 7 a a DT cord-015569-vy49r1zd 275 8 traditional traditional JJ cord-015569-vy49r1zd 275 9 Japanese japanese JJ cord-015569-vy49r1zd 275 10 fish fish NN cord-015569-vy49r1zd 275 11 broth broth NN cord-015569-vy49r1zd 275 12 that that WDT cord-015569-vy49r1zd 275 13 enhances enhance VBZ cord-015569-vy49r1zd 275 14 palatability palatability NN cord-015569-vy49r1zd 275 15 of of IN cord-015569-vy49r1zd 275 16 various various JJ cord-015569-vy49r1zd 275 17 dishes dish NNS cord-015569-vy49r1zd 275 18 due due IN cord-015569-vy49r1zd 275 19 to to IN cord-015569-vy49r1zd 275 20 its -PRON- PRP$ cord-015569-vy49r1zd 275 21 specific specific JJ cord-015569-vy49r1zd 275 22 flavor flavor NN cord-015569-vy49r1zd 275 23 . . . cord-015569-vy49r1zd 276 1 However however RB cord-015569-vy49r1zd 276 2 , , , cord-015569-vy49r1zd 276 3 the the DT cord-015569-vy49r1zd 276 4 scientific scientific JJ cord-015569-vy49r1zd 276 5 evidence evidence NN cord-015569-vy49r1zd 276 6 why why WRB cord-015569-vy49r1zd 276 7 dried dry VBN cord-015569-vy49r1zd 276 8 - - HYPH cord-015569-vy49r1zd 276 9 bonito bonito FW cord-015569-vy49r1zd 276 10 dashi dashi NN cord-015569-vy49r1zd 276 11 is be VBZ cord-015569-vy49r1zd 276 12 important important JJ cord-015569-vy49r1zd 276 13 for for IN cord-015569-vy49r1zd 276 14 Japanese japanese JJ cord-015569-vy49r1zd 276 15 dishes dish NNS cord-015569-vy49r1zd 276 16 is be VBZ cord-015569-vy49r1zd 276 17 little little RB cord-015569-vy49r1zd 276 18 known known JJ cord-015569-vy49r1zd 276 19 . . . cord-015569-vy49r1zd 277 1 In in IN cord-015569-vy49r1zd 277 2 general general JJ cord-015569-vy49r1zd 277 3 , , , cord-015569-vy49r1zd 277 4 the the DT cord-015569-vy49r1zd 277 5 main main JJ cord-015569-vy49r1zd 277 6 stimulus stimulus NN cord-015569-vy49r1zd 277 7 is be VBZ cord-015569-vy49r1zd 277 8 considered consider VBN cord-015569-vy49r1zd 277 9 as as IN cord-015569-vy49r1zd 277 10 inosinate inosinate NNP cord-015569-vy49r1zd 277 11 ( ( -LRB- cord-015569-vy49r1zd 277 12 an an DT cord-015569-vy49r1zd 277 13 umami umami NN cord-015569-vy49r1zd 277 14 substance substance NN cord-015569-vy49r1zd 277 15 ) ) -RRB- cord-015569-vy49r1zd 277 16 but but CC cord-015569-vy49r1zd 277 17 the the DT cord-015569-vy49r1zd 277 18 dashi dashi NN cord-015569-vy49r1zd 277 19 is be VBZ cord-015569-vy49r1zd 277 20 a a DT cord-015569-vy49r1zd 277 21 complex complex JJ cord-015569-vy49r1zd 277 22 mixture mixture NN cord-015569-vy49r1zd 277 23 of of IN cord-015569-vy49r1zd 277 24 many many JJ cord-015569-vy49r1zd 277 25 taste taste NN cord-015569-vy49r1zd 277 26 substances substance NNS cord-015569-vy49r1zd 277 27 such such JJ cord-015569-vy49r1zd 277 28 as as IN cord-015569-vy49r1zd 277 29 lactate lactate NN cord-015569-vy49r1zd 277 30 ( ( -LRB- cord-015569-vy49r1zd 277 31 sour sour JJ cord-015569-vy49r1zd 277 32 ) ) -RRB- cord-015569-vy49r1zd 277 33 , , , cord-015569-vy49r1zd 277 34 histidine histidine NN cord-015569-vy49r1zd 277 35 ( ( -LRB- cord-015569-vy49r1zd 277 36 bitter bitter JJ cord-015569-vy49r1zd 277 37 ) ) -RRB- cord-015569-vy49r1zd 277 38 , , , cord-015569-vy49r1zd 277 39 sodium sodium NN cord-015569-vy49r1zd 277 40 ( ( -LRB- cord-015569-vy49r1zd 277 41 salty salty JJ cord-015569-vy49r1zd 277 42 ) ) -RRB- cord-015569-vy49r1zd 277 43 and and CC cord-015569-vy49r1zd 277 44 other other JJ cord-015569-vy49r1zd 277 45 minerals mineral NNS cord-015569-vy49r1zd 277 46 ( ( -LRB- cord-015569-vy49r1zd 277 47 generally generally RB cord-015569-vy49r1zd 277 48 bitter bitter JJ cord-015569-vy49r1zd 277 49 ) ) -RRB- cord-015569-vy49r1zd 277 50 as as RB cord-015569-vy49r1zd 277 51 well well RB cord-015569-vy49r1zd 277 52 as as IN cord-015569-vy49r1zd 277 53 macromolecules macromolecule NNS cord-015569-vy49r1zd 277 54 ( ( -LRB- cord-015569-vy49r1zd 277 55 proteins protein NNS cord-015569-vy49r1zd 277 56 and and CC cord-015569-vy49r1zd 277 57 peptides peptide NNS cord-015569-vy49r1zd 277 58 ) ) -RRB- cord-015569-vy49r1zd 277 59 and and CC cord-015569-vy49r1zd 277 60 over over IN cord-015569-vy49r1zd 277 61 400 400 CD cord-015569-vy49r1zd 277 62 odorants odorant NNS cord-015569-vy49r1zd 277 63 . . . cord-015569-vy49r1zd 278 1 Here here RB cord-015569-vy49r1zd 278 2 we -PRON- PRP cord-015569-vy49r1zd 278 3 investigated investigate VBD cord-015569-vy49r1zd 278 4 mechanisms mechanism NNS cord-015569-vy49r1zd 278 5 of of IN cord-015569-vy49r1zd 278 6 preference preference NN cord-015569-vy49r1zd 278 7 for for IN cord-015569-vy49r1zd 278 8 dried dry VBN cord-015569-vy49r1zd 278 9 - - HYPH cord-015569-vy49r1zd 278 10 bonito bonito FW cord-015569-vy49r1zd 278 11 dashi dashi NNS cord-015569-vy49r1zd 278 12 using use VBG cord-015569-vy49r1zd 278 13 48-h 48-h CD cord-015569-vy49r1zd 278 14 two two CD cord-015569-vy49r1zd 278 15 - - HYPH cord-015569-vy49r1zd 278 16 bottle bottle NN cord-015569-vy49r1zd 278 17 choice choice NN cord-015569-vy49r1zd 278 18 tests test NNS cord-015569-vy49r1zd 278 19 in in IN cord-015569-vy49r1zd 278 20 adult adult NN cord-015569-vy49r1zd 278 21 male male JJ cord-015569-vy49r1zd 278 22 Sprague Sprague NNP cord-015569-vy49r1zd 278 23 - - HYPH cord-015569-vy49r1zd 278 24 Dawley Dawley NNP cord-015569-vy49r1zd 278 25 rats rat NNS cord-015569-vy49r1zd 278 26 . . . cord-015569-vy49r1zd 279 1 We -PRON- PRP cord-015569-vy49r1zd 279 2 found find VBD cord-015569-vy49r1zd 279 3 that that DT cord-015569-vy49r1zd 279 4 preference preference NN cord-015569-vy49r1zd 279 5 for for IN cord-015569-vy49r1zd 279 6 dashi dashi NNS cord-015569-vy49r1zd 279 7 was be VBD cord-015569-vy49r1zd 279 8 influenced influence VBN cord-015569-vy49r1zd 279 9 by by IN cord-015569-vy49r1zd 279 10 current current JJ cord-015569-vy49r1zd 279 11 nutrition nutrition NN cord-015569-vy49r1zd 279 12 , , , cord-015569-vy49r1zd 279 13 i.e. i.e. FW cord-015569-vy49r1zd 279 14 , , , cord-015569-vy49r1zd 279 15 ingestion ingestion NN cord-015569-vy49r1zd 279 16 of of IN cord-015569-vy49r1zd 279 17 high high JJ cord-015569-vy49r1zd 279 18 fat fat NN cord-015569-vy49r1zd 279 19 or or CC cord-015569-vy49r1zd 279 20 high high JJ cord-015569-vy49r1zd 279 21 sucrose sucrose NN cord-015569-vy49r1zd 279 22 diet diet NN cord-015569-vy49r1zd 279 23 suppressed suppress VBD cord-015569-vy49r1zd 279 24 preference preference NN cord-015569-vy49r1zd 279 25 for for IN cord-015569-vy49r1zd 279 26 dashi dashi NNS cord-015569-vy49r1zd 279 27 . . . cord-015569-vy49r1zd 280 1 In in IN cord-015569-vy49r1zd 280 2 addition addition NN cord-015569-vy49r1zd 280 3 , , , cord-015569-vy49r1zd 280 4 past past JJ cord-015569-vy49r1zd 280 5 experience experience NN cord-015569-vy49r1zd 280 6 / / SYM cord-015569-vy49r1zd 280 7 learning learning NN cord-015569-vy49r1zd 280 8 of of IN cord-015569-vy49r1zd 280 9 dashi dashi JJ cord-015569-vy49r1zd 280 10 ingestion ingestion NN cord-015569-vy49r1zd 280 11 was be VBD cord-015569-vy49r1zd 280 12 the the DT cord-015569-vy49r1zd 280 13 most most RBS cord-015569-vy49r1zd 280 14 important important JJ cord-015569-vy49r1zd 280 15 determinant determinant NN cord-015569-vy49r1zd 280 16 that that WDT cord-015569-vy49r1zd 280 17 could could MD cord-015569-vy49r1zd 280 18 overcome overcome VB cord-015569-vy49r1zd 280 19 the the DT cord-015569-vy49r1zd 280 20 influences influence NNS cord-015569-vy49r1zd 280 21 of of IN cord-015569-vy49r1zd 280 22 current current JJ cord-015569-vy49r1zd 280 23 nutrition nutrition NN cord-015569-vy49r1zd 280 24 . . . cord-015569-vy49r1zd 281 1 For for IN cord-015569-vy49r1zd 281 2 example example NN cord-015569-vy49r1zd 281 3 , , , cord-015569-vy49r1zd 281 4 preference preference NN cord-015569-vy49r1zd 281 5 of of IN cord-015569-vy49r1zd 281 6 the the DT cord-015569-vy49r1zd 281 7 threshold threshold NN cord-015569-vy49r1zd 281 8 concentrations concentration NNS cord-015569-vy49r1zd 281 9 ( ( -LRB- cord-015569-vy49r1zd 281 10 0.4 0.4 CD cord-015569-vy49r1zd 281 11 % % NN cord-015569-vy49r1zd 281 12 ) ) -RRB- cord-015569-vy49r1zd 281 13 of of IN cord-015569-vy49r1zd 281 14 dashi dashi NN cord-015569-vy49r1zd 281 15 increased increase VBD cord-015569-vy49r1zd 281 16 gradually gradually RB cord-015569-vy49r1zd 281 17 during during IN cord-015569-vy49r1zd 281 18 repeated repeat VBN cord-015569-vy49r1zd 281 19 exposure exposure NN cord-015569-vy49r1zd 281 20 to to IN cord-015569-vy49r1zd 281 21 dashi dashi JJ cord-015569-vy49r1zd 281 22 solution solution NN cord-015569-vy49r1zd 281 23 . . . cord-015569-vy49r1zd 282 1 After after IN cord-015569-vy49r1zd 282 2 the the DT cord-015569-vy49r1zd 282 3 repeated repeat VBN cord-015569-vy49r1zd 282 4 ingestion ingestion NN cord-015569-vy49r1zd 282 5 of of IN cord-015569-vy49r1zd 282 6 dashi dashi JJ cord-015569-vy49r1zd 282 7 solution solution NN cord-015569-vy49r1zd 282 8 , , , cord-015569-vy49r1zd 282 9 ingestion ingestion NN cord-015569-vy49r1zd 282 10 of of IN cord-015569-vy49r1zd 282 11 high high JJ cord-015569-vy49r1zd 282 12 fat fat NN cord-015569-vy49r1zd 282 13 or or CC cord-015569-vy49r1zd 282 14 high high JJ cord-015569-vy49r1zd 282 15 sucrose sucrose NN cord-015569-vy49r1zd 282 16 diet diet NN cord-015569-vy49r1zd 282 17 has have VBZ cord-015569-vy49r1zd 282 18 no no DT cord-015569-vy49r1zd 282 19 influence influence NN cord-015569-vy49r1zd 282 20 on on IN cord-015569-vy49r1zd 282 21 dashi dashi JJ cord-015569-vy49r1zd 282 22 preference preference NN cord-015569-vy49r1zd 282 23 . . . cord-015569-vy49r1zd 283 1 In in IN cord-015569-vy49r1zd 283 2 the the DT cord-015569-vy49r1zd 283 3 descending descend VBG cord-015569-vy49r1zd 283 4 concentration concentration NN cord-015569-vy49r1zd 283 5 series series NN cord-015569-vy49r1zd 283 6 , , , cord-015569-vy49r1zd 283 7 the the DT cord-015569-vy49r1zd 283 8 concentration concentration NN cord-015569-vy49r1zd 283 9 - - HYPH cord-015569-vy49r1zd 283 10 preference preference NN cord-015569-vy49r1zd 283 11 function function NN cord-015569-vy49r1zd 283 12 shifted shift VBD cord-015569-vy49r1zd 283 13 100-fold 100-fold CD cord-015569-vy49r1zd 283 14 to to IN cord-015569-vy49r1zd 283 15 the the DT cord-015569-vy49r1zd 283 16 lower low JJR cord-015569-vy49r1zd 283 17 concentrations concentration NNS cord-015569-vy49r1zd 283 18 compared compare VBN cord-015569-vy49r1zd 283 19 with with IN cord-015569-vy49r1zd 283 20 the the DT cord-015569-vy49r1zd 283 21 ascending ascend VBG cord-015569-vy49r1zd 283 22 one one CD cord-015569-vy49r1zd 283 23 . . . cord-015569-vy49r1zd 284 1 These these DT cord-015569-vy49r1zd 284 2 results result NNS cord-015569-vy49r1zd 284 3 suggested suggest VBD cord-015569-vy49r1zd 284 4 that that IN cord-015569-vy49r1zd 284 5 postingestive postingestive JJ cord-015569-vy49r1zd 284 6 consequences consequence NNS cord-015569-vy49r1zd 284 7 as as RB cord-015569-vy49r1zd 284 8 well well RB cord-015569-vy49r1zd 284 9 as as IN cord-015569-vy49r1zd 284 10 oronasal oronasal NN cord-015569-vy49r1zd 284 11 sensations sensation NNS cord-015569-vy49r1zd 284 12 guide guide VBP cord-015569-vy49r1zd 284 13 the the DT cord-015569-vy49r1zd 284 14 preference preference NN cord-015569-vy49r1zd 284 15 for for IN cord-015569-vy49r1zd 284 16 dashi dashi JJ cord-015569-vy49r1zd 284 17 solutions solution NNS cord-015569-vy49r1zd 284 18 that that WDT cord-015569-vy49r1zd 284 19 are be VBP cord-015569-vy49r1zd 284 20 under under IN cord-015569-vy49r1zd 284 21 the the DT cord-015569-vy49r1zd 284 22 control control NN cord-015569-vy49r1zd 284 23 of of IN cord-015569-vy49r1zd 284 24 current current JJ cord-015569-vy49r1zd 284 25 nutrition nutrition NN cord-015569-vy49r1zd 284 26 and and CC cord-015569-vy49r1zd 284 27 past past NN cord-015569-vy49r1zd 284 28 experience experience NN cord-015569-vy49r1zd 284 29 / / SYM cord-015569-vy49r1zd 284 30 learning learning NN cord-015569-vy49r1zd 284 31 . . . cord-015569-vy49r1zd 285 1 Food food NN cord-015569-vy49r1zd 285 2 aversion aversion NN cord-015569-vy49r1zd 285 3 learning learning NN cord-015569-vy49r1zd 285 4 is be VBZ cord-015569-vy49r1zd 285 5 the the DT cord-015569-vy49r1zd 285 6 long long JJ cord-015569-vy49r1zd 285 7 - - HYPH cord-015569-vy49r1zd 285 8 term term NN cord-015569-vy49r1zd 285 9 memory memory NN cord-015569-vy49r1zd 285 10 established establish VBN cord-015569-vy49r1zd 285 11 after after IN cord-015569-vy49r1zd 285 12 association association NN cord-015569-vy49r1zd 285 13 of of IN cord-015569-vy49r1zd 285 14 the the DT cord-015569-vy49r1zd 285 15 properties property NNS cord-015569-vy49r1zd 285 16 of of IN cord-015569-vy49r1zd 285 17 food food NN cord-015569-vy49r1zd 285 18 , , , cord-015569-vy49r1zd 285 19 such such JJ cord-015569-vy49r1zd 285 20 as as IN cord-015569-vy49r1zd 285 21 texture texture NN cord-015569-vy49r1zd 285 22 and and CC cord-015569-vy49r1zd 285 23 taste taste NN cord-015569-vy49r1zd 285 24 ( ( -LRB- cord-015569-vy49r1zd 285 25 conditioned condition VBN cord-015569-vy49r1zd 285 26 stimulus stimulus NN cord-015569-vy49r1zd 285 27 , , , cord-015569-vy49r1zd 285 28 CS CS NNP cord-015569-vy49r1zd 285 29 ) ) -RRB- cord-015569-vy49r1zd 285 30 , , , cord-015569-vy49r1zd 285 31 with with IN cord-015569-vy49r1zd 285 32 visceral visceral JJ cord-015569-vy49r1zd 285 33 malaise malaise NN cord-015569-vy49r1zd 285 34 ( ( -LRB- cord-015569-vy49r1zd 285 35 unconditioned unconditioned JJ cord-015569-vy49r1zd 285 36 stimulus stimulus NN cord-015569-vy49r1zd 285 37 , , , cord-015569-vy49r1zd 285 38 US US NNP cord-015569-vy49r1zd 285 39 ) ) -RRB- cord-015569-vy49r1zd 285 40 . . . cord-015569-vy49r1zd 286 1 After after IN cord-015569-vy49r1zd 286 2 the the DT cord-015569-vy49r1zd 286 3 acquisition acquisition NN cord-015569-vy49r1zd 286 4 of of IN cord-015569-vy49r1zd 286 5 the the DT cord-015569-vy49r1zd 286 6 learning learning NN cord-015569-vy49r1zd 286 7 , , , cord-015569-vy49r1zd 286 8 the the DT cord-015569-vy49r1zd 286 9 re re NN cord-015569-vy49r1zd 286 10 - - NN cord-015569-vy49r1zd 286 11 exposure exposure NN cord-015569-vy49r1zd 286 12 to to IN cord-015569-vy49r1zd 286 13 the the DT cord-015569-vy49r1zd 286 14 CS CS NNP cord-015569-vy49r1zd 286 15 induces induce VBZ cord-015569-vy49r1zd 286 16 the the DT cord-015569-vy49r1zd 286 17 retrieval retrieval NN cord-015569-vy49r1zd 286 18 of of IN cord-015569-vy49r1zd 286 19 the the DT cord-015569-vy49r1zd 286 20 memory memory NN cord-015569-vy49r1zd 286 21 and and CC cord-015569-vy49r1zd 286 22 the the DT cord-015569-vy49r1zd 286 23 rejection rejection NN cord-015569-vy49r1zd 286 24 of of IN cord-015569-vy49r1zd 286 25 the the DT cord-015569-vy49r1zd 286 26 CS CS NNP cord-015569-vy49r1zd 286 27 occurs occur VBZ cord-015569-vy49r1zd 286 28 . . . cord-015569-vy49r1zd 287 1 Previously previously RB cord-015569-vy49r1zd 287 2 , , , cord-015569-vy49r1zd 287 3 we -PRON- PRP cord-015569-vy49r1zd 287 4 showed show VBD cord-015569-vy49r1zd 287 5 that that IN cord-015569-vy49r1zd 287 6 histamine histamine NN cord-015569-vy49r1zd 287 7 release release NN cord-015569-vy49r1zd 287 8 in in IN cord-015569-vy49r1zd 287 9 the the DT cord-015569-vy49r1zd 287 10 central central JJ cord-015569-vy49r1zd 287 11 nucleus nucleus NN cord-015569-vy49r1zd 287 12 of of IN cord-015569-vy49r1zd 287 13 amygdala amygdala NNP cord-015569-vy49r1zd 287 14 ( ( -LRB- cord-015569-vy49r1zd 287 15 CeA CeA NNP cord-015569-vy49r1zd 287 16 ) ) -RRB- cord-015569-vy49r1zd 287 17 during during IN cord-015569-vy49r1zd 287 18 the the DT cord-015569-vy49r1zd 287 19 re re NN cord-015569-vy49r1zd 287 20 - - NN cord-015569-vy49r1zd 287 21 exposure exposure NN cord-015569-vy49r1zd 287 22 to to IN cord-015569-vy49r1zd 287 23 the the DT cord-015569-vy49r1zd 287 24 CS CS NNP cord-015569-vy49r1zd 287 25 was be VBD cord-015569-vy49r1zd 287 26 increased increase VBN cord-015569-vy49r1zd 287 27 in in IN cord-015569-vy49r1zd 287 28 soft soft JJ cord-015569-vy49r1zd 287 29 pellets pellet NNS cord-015569-vy49r1zd 287 30 - - HYPH cord-015569-vy49r1zd 287 31 conditioned condition VBN cord-015569-vy49r1zd 287 32 rats rat NNS cord-015569-vy49r1zd 287 33 , , , cord-015569-vy49r1zd 287 34 but but CC cord-015569-vy49r1zd 287 35 not not RB cord-015569-vy49r1zd 287 36 in in IN cord-015569-vy49r1zd 287 37 sweet sweet JJ cord-015569-vy49r1zd 287 38 pellets pellet NNS cord-015569-vy49r1zd 287 39 - - HYPH cord-015569-vy49r1zd 287 40 conditioned condition VBN cord-015569-vy49r1zd 287 41 rats rat NNS cord-015569-vy49r1zd 287 42 . . . cord-015569-vy49r1zd 288 1 In in IN cord-015569-vy49r1zd 288 2 the the DT cord-015569-vy49r1zd 288 3 present present JJ cord-015569-vy49r1zd 288 4 study study NN cord-015569-vy49r1zd 288 5 , , , cord-015569-vy49r1zd 288 6 we -PRON- PRP cord-015569-vy49r1zd 288 7 studied study VBD cord-015569-vy49r1zd 288 8 the the DT cord-015569-vy49r1zd 288 9 role role NN cord-015569-vy49r1zd 288 10 of of IN cord-015569-vy49r1zd 288 11 the the DT cord-015569-vy49r1zd 288 12 histaminergic histaminergic JJ cord-015569-vy49r1zd 288 13 transmission transmission NN cord-015569-vy49r1zd 288 14 in in IN cord-015569-vy49r1zd 288 15 the the DT cord-015569-vy49r1zd 288 16 CeA CeA NNP cord-015569-vy49r1zd 288 17 in in IN cord-015569-vy49r1zd 288 18 the the DT cord-015569-vy49r1zd 288 19 retrieval retrieval NN cord-015569-vy49r1zd 288 20 of of IN cord-015569-vy49r1zd 288 21 food food NN cord-015569-vy49r1zd 288 22 aversion aversion NN cord-015569-vy49r1zd 288 23 learning learning NN cord-015569-vy49r1zd 288 24 induced induce VBN cord-015569-vy49r1zd 288 25 by by IN cord-015569-vy49r1zd 288 26 two two CD cord-015569-vy49r1zd 288 27 patterns pattern NNS cord-015569-vy49r1zd 288 28 of of IN cord-015569-vy49r1zd 288 29 the the DT cord-015569-vy49r1zd 288 30 CS CS NNP cord-015569-vy49r1zd 288 31 . . . cord-015569-vy49r1zd 288 32 Fos Fos NNP cord-015569-vy49r1zd 288 33 expression expression NN cord-015569-vy49r1zd 288 34 , , , cord-015569-vy49r1zd 288 35 a a DT cord-015569-vy49r1zd 288 36 marker marker NN cord-015569-vy49r1zd 288 37 of of IN cord-015569-vy49r1zd 288 38 neuronal neuronal JJ cord-015569-vy49r1zd 288 39 activation activation NN cord-015569-vy49r1zd 288 40 , , , cord-015569-vy49r1zd 288 41 following follow VBG cord-015569-vy49r1zd 288 42 the the DT cord-015569-vy49r1zd 288 43 retrieval retrieval NN cord-015569-vy49r1zd 288 44 of of IN cord-015569-vy49r1zd 288 45 food food NN cord-015569-vy49r1zd 288 46 aversion aversion NN cord-015569-vy49r1zd 288 47 learning learning NN cord-015569-vy49r1zd 288 48 induced induce VBN cord-015569-vy49r1zd 288 49 by by IN cord-015569-vy49r1zd 288 50 each each DT cord-015569-vy49r1zd 288 51 CS CS NNP cord-015569-vy49r1zd 288 52 ( ( -LRB- cord-015569-vy49r1zd 288 53 soft soft JJ cord-015569-vy49r1zd 288 54 pellets pellet NNS cord-015569-vy49r1zd 288 55 or or CC cord-015569-vy49r1zd 288 56 sweet sweet JJ cord-015569-vy49r1zd 288 57 pellets pellet NNS cord-015569-vy49r1zd 288 58 ) ) -RRB- cord-015569-vy49r1zd 288 59 and and CC cord-015569-vy49r1zd 288 60 US US NNP cord-015569-vy49r1zd 288 61 pairing pair VBG cord-015569-vy49r1zd 288 62 was be VBD cord-015569-vy49r1zd 288 63 examined examine VBN cord-015569-vy49r1zd 288 64 . . . cord-015569-vy49r1zd 289 1 Few few JJ cord-015569-vy49r1zd 289 2 Fos Fos NNP cord-015569-vy49r1zd 289 3 - - HYPH cord-015569-vy49r1zd 289 4 positive positive JJ cord-015569-vy49r1zd 289 5 cells cell NNS cord-015569-vy49r1zd 289 6 in in IN cord-015569-vy49r1zd 289 7 the the DT cord-015569-vy49r1zd 289 8 CeA CeA NNP cord-015569-vy49r1zd 289 9 were be VBD cord-015569-vy49r1zd 289 10 observed observe VBN cord-015569-vy49r1zd 289 11 by by IN cord-015569-vy49r1zd 289 12 consuming consume VBG cord-015569-vy49r1zd 289 13 both both DT cord-015569-vy49r1zd 289 14 types type NNS cord-015569-vy49r1zd 289 15 of of IN cord-015569-vy49r1zd 289 16 pellets pellet NNS cord-015569-vy49r1zd 289 17 in in IN cord-015569-vy49r1zd 289 18 naïve naïve JJ cord-015569-vy49r1zd 289 19 rats rat NNS cord-015569-vy49r1zd 289 20 . . . cord-015569-vy49r1zd 290 1 In in IN cord-015569-vy49r1zd 290 2 the the DT cord-015569-vy49r1zd 290 3 conditioned condition VBN cord-015569-vy49r1zd 290 4 rats rat NNS cord-015569-vy49r1zd 290 5 , , , cord-015569-vy49r1zd 290 6 Fos Fos NNP cord-015569-vy49r1zd 290 7 expression expression NN cord-015569-vy49r1zd 290 8 in in IN cord-015569-vy49r1zd 290 9 the the DT cord-015569-vy49r1zd 290 10 CeA CeA NNP cord-015569-vy49r1zd 290 11 was be VBD cord-015569-vy49r1zd 290 12 increased increase VBN cord-015569-vy49r1zd 290 13 in in IN cord-015569-vy49r1zd 290 14 response response NN cord-015569-vy49r1zd 290 15 to to IN cord-015569-vy49r1zd 290 16 the the DT cord-015569-vy49r1zd 290 17 re re NN cord-015569-vy49r1zd 290 18 - - NN cord-015569-vy49r1zd 290 19 exposure exposure NN cord-015569-vy49r1zd 290 20 to to IN cord-015569-vy49r1zd 290 21 soft soft JJ cord-015569-vy49r1zd 290 22 pellets pellet NNS cord-015569-vy49r1zd 290 23 while while IN cord-015569-vy49r1zd 290 24 it -PRON- PRP cord-015569-vy49r1zd 290 25 was be VBD cord-015569-vy49r1zd 290 26 not not RB cord-015569-vy49r1zd 290 27 elevated elevate VBN cord-015569-vy49r1zd 290 28 by by IN cord-015569-vy49r1zd 290 29 the the DT cord-015569-vy49r1zd 290 30 re re NN cord-015569-vy49r1zd 290 31 - - NN cord-015569-vy49r1zd 290 32 exposure exposure NN cord-015569-vy49r1zd 290 33 to to IN cord-015569-vy49r1zd 290 34 sweet sweet JJ cord-015569-vy49r1zd 290 35 pellets pellet NNS cord-015569-vy49r1zd 290 36 . . . cord-015569-vy49r1zd 291 1 In in IN cord-015569-vy49r1zd 291 2 addition addition NN cord-015569-vy49r1zd 291 3 , , , cord-015569-vy49r1zd 291 4 the the DT cord-015569-vy49r1zd 291 5 microinjection microinjection NN cord-015569-vy49r1zd 291 6 of of IN cord-015569-vy49r1zd 291 7 H H NNP cord-015569-vy49r1zd 291 8 1 1 CD cord-015569-vy49r1zd 291 9 -antagonist -antagonist NN cord-015569-vy49r1zd 291 10 to to IN cord-015569-vy49r1zd 291 11 the the DT cord-015569-vy49r1zd 291 12 bilateral bilateral JJ cord-015569-vy49r1zd 291 13 CeA cea NN cord-015569-vy49r1zd 291 14 just just RB cord-015569-vy49r1zd 291 15 before before IN cord-015569-vy49r1zd 291 16 the the DT cord-015569-vy49r1zd 291 17 re re NN cord-015569-vy49r1zd 291 18 - - NN cord-015569-vy49r1zd 291 19 exposure exposure NN cord-015569-vy49r1zd 291 20 to to IN cord-015569-vy49r1zd 291 21 the the DT cord-015569-vy49r1zd 291 22 CS CS NNP cord-015569-vy49r1zd 291 23 impaired impair VBD cord-015569-vy49r1zd 291 24 the the DT cord-015569-vy49r1zd 291 25 aversive aversive JJ cord-015569-vy49r1zd 291 26 response response NN cord-015569-vy49r1zd 291 27 to to IN cord-015569-vy49r1zd 291 28 soft soft JJ cord-015569-vy49r1zd 291 29 pellets pellet NNS cord-015569-vy49r1zd 291 30 but but CC cord-015569-vy49r1zd 291 31 not not RB cord-015569-vy49r1zd 291 32 to to IN cord-015569-vy49r1zd 291 33 sweet sweet JJ cord-015569-vy49r1zd 291 34 pellets pellet NNS cord-015569-vy49r1zd 291 35 . . . cord-015569-vy49r1zd 292 1 These these DT cord-015569-vy49r1zd 292 2 findings finding NNS cord-015569-vy49r1zd 292 3 indicate indicate VBP cord-015569-vy49r1zd 292 4 that that IN cord-015569-vy49r1zd 292 5 the the DT cord-015569-vy49r1zd 292 6 neuronal neuronal JJ cord-015569-vy49r1zd 292 7 activation activation NN cord-015569-vy49r1zd 292 8 through through IN cord-015569-vy49r1zd 292 9 the the DT cord-015569-vy49r1zd 292 10 histaminergic histaminergic JJ cord-015569-vy49r1zd 292 11 system system NN cord-015569-vy49r1zd 292 12 via via IN cord-015569-vy49r1zd 292 13 H h NN cord-015569-vy49r1zd 292 14 1 1 CD cord-015569-vy49r1zd 292 15 receptor receptor NN cord-015569-vy49r1zd 292 16 is be VBZ cord-015569-vy49r1zd 292 17 involved involve VBN cord-015569-vy49r1zd 292 18 in in IN cord-015569-vy49r1zd 292 19 the the DT cord-015569-vy49r1zd 292 20 retrieval retrieval NN cord-015569-vy49r1zd 292 21 of of IN cord-015569-vy49r1zd 292 22 texture texture NN cord-015569-vy49r1zd 292 23 aversion aversion NN cord-015569-vy49r1zd 292 24 learning learning NN cord-015569-vy49r1zd 292 25 but but CC cord-015569-vy49r1zd 292 26 not not RB cord-015569-vy49r1zd 292 27 in in IN cord-015569-vy49r1zd 292 28 that that DT cord-015569-vy49r1zd 292 29 of of IN cord-015569-vy49r1zd 292 30 taste taste NN cord-015569-vy49r1zd 292 31 aversion aversion NN cord-015569-vy49r1zd 292 32 learning learning NN cord-015569-vy49r1zd 292 33 . . . cord-015569-vy49r1zd 293 1 # # $ cord-015569-vy49r1zd 293 2 27 27 CD cord-015569-vy49r1zd 293 3 Food food NN cord-015569-vy49r1zd 293 4 entrained entrain VBN cord-015569-vy49r1zd 293 5 feeding feeding NN cord-015569-vy49r1zd 293 6 behavior behavior NN cord-015569-vy49r1zd 293 7 to to IN cord-015569-vy49r1zd 293 8 highly highly RB cord-015569-vy49r1zd 293 9 sweet sweet JJ cord-015569-vy49r1zd 293 10 food food NN cord-015569-vy49r1zd 293 11 in in IN cord-015569-vy49r1zd 293 12 non non JJ cord-015569-vy49r1zd 293 13 - - JJ cord-015569-vy49r1zd 293 14 food food JJ cord-015569-vy49r1zd 293 15 deprived deprive VBN cord-015569-vy49r1zd 293 16 mice mouse NNS cord-015569-vy49r1zd 293 17 Yasunobu Yasunobu NNP cord-015569-vy49r1zd 293 18 Yasoshima Yasoshima NNP cord-015569-vy49r1zd 293 19 , , , cord-015569-vy49r1zd 293 20 Megumi Megumi NNP cord-015569-vy49r1zd 293 21 Tanibuchi Tanibuchi NNP cord-015569-vy49r1zd 293 22 and and CC cord-015569-vy49r1zd 293 23 Tsuyoshi Tsuyoshi NNP cord-015569-vy49r1zd 293 24 Shimura Shimura NNP cord-015569-vy49r1zd 293 25 Division Division NNP cord-015569-vy49r1zd 293 26 of of IN cord-015569-vy49r1zd 293 27 Behavioral Behavioral NNP cord-015569-vy49r1zd 293 28 Physiology Physiology NNP cord-015569-vy49r1zd 293 29 , , , cord-015569-vy49r1zd 293 30 Department Department NNP cord-015569-vy49r1zd 293 31 of of IN cord-015569-vy49r1zd 293 32 Behavioral Behavioral NNP cord-015569-vy49r1zd 293 33 Sciences Sciences NNPS cord-015569-vy49r1zd 293 34 , , , cord-015569-vy49r1zd 293 35 Graduate Graduate NNP cord-015569-vy49r1zd 293 36 School School NNP cord-015569-vy49r1zd 293 37 of of IN cord-015569-vy49r1zd 293 38 Human Human NNP cord-015569-vy49r1zd 293 39 Sciences Sciences NNPS cord-015569-vy49r1zd 293 40 , , , cord-015569-vy49r1zd 293 41 Osaka Osaka NNP cord-015569-vy49r1zd 293 42 University University NNP cord-015569-vy49r1zd 293 43 , , , cord-015569-vy49r1zd 293 44 Suita Suita NNP cord-015569-vy49r1zd 293 45 565 565 CD cord-015569-vy49r1zd 293 46 - - HYPH cord-015569-vy49r1zd 293 47 0871 0871 CD cord-015569-vy49r1zd 294 1 , , , cord-015569-vy49r1zd 294 2 Japan Japan NNP cord-015569-vy49r1zd 294 3 Light Light NNP cord-015569-vy49r1zd 294 4 - - HYPH cord-015569-vy49r1zd 294 5 regulated regulate VBN cord-015569-vy49r1zd 294 6 circadian circadian NN cord-015569-vy49r1zd 294 7 clock clock NN cord-015569-vy49r1zd 294 8 in in IN cord-015569-vy49r1zd 294 9 each each DT cord-015569-vy49r1zd 294 10 animal animal NN cord-015569-vy49r1zd 294 11 species species NN cord-015569-vy49r1zd 294 12 affects affect VBZ cord-015569-vy49r1zd 294 13 its -PRON- PRP$ cord-015569-vy49r1zd 294 14 original original JJ cord-015569-vy49r1zd 294 15 feeding feeding NN cord-015569-vy49r1zd 294 16 rhythm rhythm NN cord-015569-vy49r1zd 294 17 . . . cord-015569-vy49r1zd 295 1 Nocturnal nocturnal JJ cord-015569-vy49r1zd 295 2 rodents rodent NNS cord-015569-vy49r1zd 295 3 mainly mainly RB cord-015569-vy49r1zd 295 4 consume consume VBP cord-015569-vy49r1zd 295 5 food food NN cord-015569-vy49r1zd 295 6 during during IN cord-015569-vy49r1zd 295 7 the the DT cord-015569-vy49r1zd 295 8 dark dark JJ cord-015569-vy49r1zd 295 9 phase phase NN cord-015569-vy49r1zd 295 10 under under IN cord-015569-vy49r1zd 295 11 ad ad NN cord-015569-vy49r1zd 295 12 libitum libitum FW cord-015569-vy49r1zd 295 13 food food NN cord-015569-vy49r1zd 295 14 condition condition NN cord-015569-vy49r1zd 295 15 ; ; : cord-015569-vy49r1zd 295 16 however however RB cord-015569-vy49r1zd 295 17 , , , cord-015569-vy49r1zd 295 18 their -PRON- PRP$ cord-015569-vy49r1zd 295 19 daily daily JJ cord-015569-vy49r1zd 295 20 feeding feeding NN cord-015569-vy49r1zd 295 21 rhythm rhythm NN cord-015569-vy49r1zd 295 22 is be VBZ cord-015569-vy49r1zd 295 23 entrained entrain VBN cord-015569-vy49r1zd 295 24 to to IN cord-015569-vy49r1zd 295 25 mealtime mealtime NN cord-015569-vy49r1zd 295 26 when when WRB cord-015569-vy49r1zd 295 27 they -PRON- PRP cord-015569-vy49r1zd 295 28 are be VBP cord-015569-vy49r1zd 295 29 restricted restrict VBN cord-015569-vy49r1zd 295 30 of of IN cord-015569-vy49r1zd 295 31 food food NN cord-015569-vy49r1zd 295 32 . . . cord-015569-vy49r1zd 296 1 Food food NN cord-015569-vy49r1zd 296 2 - - HYPH cord-015569-vy49r1zd 296 3 entrainment entrainment NN cord-015569-vy49r1zd 296 4 is be VBZ cord-015569-vy49r1zd 296 5 suggested suggest VBN cord-015569-vy49r1zd 296 6 to to TO cord-015569-vy49r1zd 296 7 be be VB cord-015569-vy49r1zd 296 8 mediated mediate VBN cord-015569-vy49r1zd 296 9 by by IN cord-015569-vy49r1zd 296 10 increased increase VBN cord-015569-vy49r1zd 296 11 arousal arousal NN cord-015569-vy49r1zd 296 12 and and CC cord-015569-vy49r1zd 296 13 food food NN cord-015569-vy49r1zd 296 14 - - HYPH cord-015569-vy49r1zd 296 15 oriented orient VBN cord-015569-vy49r1zd 296 16 motivation motivation NN cord-015569-vy49r1zd 296 17 derived derive VBN cord-015569-vy49r1zd 296 18 from from IN cord-015569-vy49r1zd 296 19 calorie calorie JJ cord-015569-vy49r1zd 296 20 deficiency deficiency NN cord-015569-vy49r1zd 296 21 , , , cord-015569-vy49r1zd 296 22 but but CC cord-015569-vy49r1zd 296 23 recent recent JJ cord-015569-vy49r1zd 296 24 studies study NNS cord-015569-vy49r1zd 296 25 indicate indicate VBP cord-015569-vy49r1zd 296 26 that that IN cord-015569-vy49r1zd 296 27 taste taste VBP cord-015569-vy49r1zd 296 28 palatability palatability NN cord-015569-vy49r1zd 296 29 seems seem VBZ cord-015569-vy49r1zd 296 30 to to TO cord-015569-vy49r1zd 296 31 be be VB cord-015569-vy49r1zd 296 32 important important JJ cord-015569-vy49r1zd 296 33 in in IN cord-015569-vy49r1zd 296 34 food food NN cord-015569-vy49r1zd 296 35 - - HYPH cord-015569-vy49r1zd 296 36 entrainment entrainment NN cord-015569-vy49r1zd 296 37 . . . cord-015569-vy49r1zd 297 1 However however RB cord-015569-vy49r1zd 297 2 , , , cord-015569-vy49r1zd 297 3 the the DT cord-015569-vy49r1zd 297 4 role role NN cord-015569-vy49r1zd 297 5 of of IN cord-015569-vy49r1zd 297 6 taste taste NN cord-015569-vy49r1zd 297 7 palatability palatability NN cord-015569-vy49r1zd 297 8 ( ( -LRB- cord-015569-vy49r1zd 297 9 hedonic hedonic JJ cord-015569-vy49r1zd 297 10 aspect aspect NN cord-015569-vy49r1zd 297 11 of of IN cord-015569-vy49r1zd 297 12 taste taste NN cord-015569-vy49r1zd 297 13 ) ) -RRB- cord-015569-vy49r1zd 297 14 in in IN cord-015569-vy49r1zd 297 15 food food NN cord-015569-vy49r1zd 297 16 - - HYPH cord-015569-vy49r1zd 297 17 entrainment entrainment NN cord-015569-vy49r1zd 297 18 remains remain VBZ cord-015569-vy49r1zd 297 19 not not RB cord-015569-vy49r1zd 297 20 fully fully RB cord-015569-vy49r1zd 297 21 understood understand VBN cord-015569-vy49r1zd 297 22 . . . cord-015569-vy49r1zd 298 1 To to TO cord-015569-vy49r1zd 298 2 study study VB cord-015569-vy49r1zd 298 3 the the DT cord-015569-vy49r1zd 298 4 issue issue NN cord-015569-vy49r1zd 298 5 , , , cord-015569-vy49r1zd 298 6 we -PRON- PRP cord-015569-vy49r1zd 298 7 developed develop VBD cord-015569-vy49r1zd 298 8 a a DT cord-015569-vy49r1zd 298 9 new new JJ cord-015569-vy49r1zd 298 10 , , , cord-015569-vy49r1zd 298 11 simple simple JJ cord-015569-vy49r1zd 298 12 mouse mouse NN cord-015569-vy49r1zd 298 13 model model NN cord-015569-vy49r1zd 298 14 . . . cord-015569-vy49r1zd 299 1 Ad ad NN cord-015569-vy49r1zd 299 2 libitum libitum NN cord-015569-vy49r1zd 299 3 - - HYPH cord-015569-vy49r1zd 299 4 fed feed VBN cord-015569-vy49r1zd 299 5 C57BL/6J C57BL/6J NNP cord-015569-vy49r1zd 299 6 male male JJ cord-015569-vy49r1zd 299 7 mice mouse NNS cord-015569-vy49r1zd 299 8 received receive VBD cord-015569-vy49r1zd 299 9 daily daily JJ cord-015569-vy49r1zd 299 10 limited limited JJ cord-015569-vy49r1zd 299 11 access access NN cord-015569-vy49r1zd 299 12 to to IN cord-015569-vy49r1zd 299 13 highly highly RB cord-015569-vy49r1zd 299 14 sweet sweet JJ cord-015569-vy49r1zd 299 15 chow chow NN cord-015569-vy49r1zd 299 16 ( ( -LRB- cord-015569-vy49r1zd 299 17 HSC HSC NNP cord-015569-vy49r1zd 299 18 ) ) -RRB- cord-015569-vy49r1zd 299 19 containing contain VBG cord-015569-vy49r1zd 299 20 65 65 CD cord-015569-vy49r1zd 299 21 % % NN cord-015569-vy49r1zd 299 22 sucrose sucrose NN cord-015569-vy49r1zd 299 23 for for IN cord-015569-vy49r1zd 299 24 2 2 CD cord-015569-vy49r1zd 299 25 hours hour NNS cord-015569-vy49r1zd 299 26 in in IN cord-015569-vy49r1zd 299 27 the the DT cord-015569-vy49r1zd 299 28 light light JJ cord-015569-vy49r1zd 299 29 phase phase NN cord-015569-vy49r1zd 299 30 ( ( -LRB- cord-015569-vy49r1zd 299 31 9:00 9:00 CD cord-015569-vy49r1zd 299 32 - - SYM cord-015569-vy49r1zd 299 33 11:00 11:00 CD cord-015569-vy49r1zd 299 34 a.m. a.m. NN cord-015569-vy49r1zd 299 35 ) ) -RRB- cord-015569-vy49r1zd 299 36 . . . cord-015569-vy49r1zd 300 1 They -PRON- PRP cord-015569-vy49r1zd 300 2 received receive VBD cord-015569-vy49r1zd 300 3 the the DT cord-015569-vy49r1zd 300 4 regimen regimen NN cord-015569-vy49r1zd 300 5 for for IN cord-015569-vy49r1zd 300 6 14 14 CD cord-015569-vy49r1zd 300 7 days day NNS cord-015569-vy49r1zd 300 8 as as IN cord-015569-vy49r1zd 300 9 training training NN cord-015569-vy49r1zd 300 10 . . . cord-015569-vy49r1zd 301 1 The the DT cord-015569-vy49r1zd 301 2 intake intake NN cord-015569-vy49r1zd 301 3 of of IN cord-015569-vy49r1zd 301 4 HSC HSC NNP cord-015569-vy49r1zd 301 5 gradually gradually RB cord-015569-vy49r1zd 301 6 increased increase VBD cord-015569-vy49r1zd 301 7 and and CC cord-015569-vy49r1zd 301 8 was be VBD cord-015569-vy49r1zd 301 9 about about RB cord-015569-vy49r1zd 301 10 11-fold 11-fold CD cord-015569-vy49r1zd 301 11 greater great JJR cord-015569-vy49r1zd 301 12 than than IN cord-015569-vy49r1zd 301 13 their -PRON- PRP$ cord-015569-vy49r1zd 301 14 basal basal NN cord-015569-vy49r1zd 301 15 intake intake NN cord-015569-vy49r1zd 301 16 of of IN cord-015569-vy49r1zd 301 17 normal normal JJ cord-015569-vy49r1zd 301 18 chow chow NN cord-015569-vy49r1zd 301 19 at at IN cord-015569-vy49r1zd 301 20 the the DT cord-015569-vy49r1zd 301 21 corresponding corresponding JJ cord-015569-vy49r1zd 301 22 period period NN cord-015569-vy49r1zd 301 23 of of IN cord-015569-vy49r1zd 301 24 time time NN cord-015569-vy49r1zd 301 25 during during IN cord-015569-vy49r1zd 301 26 pretraining pretraining NN cord-015569-vy49r1zd 301 27 phase phase NN cord-015569-vy49r1zd 301 28 . . . cord-015569-vy49r1zd 302 1 On on IN cord-015569-vy49r1zd 302 2 the the DT cord-015569-vy49r1zd 302 3 other other JJ cord-015569-vy49r1zd 302 4 hand hand NN cord-015569-vy49r1zd 302 5 , , , cord-015569-vy49r1zd 302 6 the the DT cord-015569-vy49r1zd 302 7 intake intake NN cord-015569-vy49r1zd 302 8 of of IN cord-015569-vy49r1zd 302 9 normal normal JJ cord-015569-vy49r1zd 302 10 chow chow NN cord-015569-vy49r1zd 302 11 in in IN cord-015569-vy49r1zd 302 12 another another DT cord-015569-vy49r1zd 302 13 group group NN cord-015569-vy49r1zd 302 14 during during IN cord-015569-vy49r1zd 302 15 the the DT cord-015569-vy49r1zd 302 16 corresponding corresponding JJ cord-015569-vy49r1zd 302 17 timing timing NN cord-015569-vy49r1zd 302 18 did do VBD cord-015569-vy49r1zd 302 19 not not RB cord-015569-vy49r1zd 302 20 increase increase VB cord-015569-vy49r1zd 302 21 . . . cord-015569-vy49r1zd 303 1 Intake intake NN cord-015569-vy49r1zd 303 2 of of IN cord-015569-vy49r1zd 303 3 normal normal JJ cord-015569-vy49r1zd 303 4 chow chow NN cord-015569-vy49r1zd 303 5 during during IN cord-015569-vy49r1zd 303 6 the the DT cord-015569-vy49r1zd 303 7 dark dark JJ cord-015569-vy49r1zd 303 8 phase phase NN cord-015569-vy49r1zd 303 9 in in IN cord-015569-vy49r1zd 303 10 mice mouse NNS cord-015569-vy49r1zd 303 11 group group NN cord-015569-vy49r1zd 303 12 receiving receive VBG cord-015569-vy49r1zd 303 13 HSC HSC NNP cord-015569-vy49r1zd 303 14 , , , cord-015569-vy49r1zd 303 15 but but CC cord-015569-vy49r1zd 303 16 not not RB cord-015569-vy49r1zd 303 17 normal normal JJ cord-015569-vy49r1zd 303 18 chow chow NN cord-015569-vy49r1zd 303 19 , , , cord-015569-vy49r1zd 303 20 significantly significantly RB cord-015569-vy49r1zd 303 21 decreased decrease VBD cord-015569-vy49r1zd 303 22 during during IN cord-015569-vy49r1zd 303 23 the the DT cord-015569-vy49r1zd 303 24 training training NN cord-015569-vy49r1zd 303 25 . . . cord-015569-vy49r1zd 304 1 The the DT cord-015569-vy49r1zd 304 2 entrained entrained JJ cord-015569-vy49r1zd 304 3 increase increase NN cord-015569-vy49r1zd 304 4 of of IN cord-015569-vy49r1zd 304 5 HSC HSC NNP cord-015569-vy49r1zd 304 6 intake intake NN cord-015569-vy49r1zd 304 7 was be VBD cord-015569-vy49r1zd 304 8 also also RB cord-015569-vy49r1zd 304 9 observed observe VBN cord-015569-vy49r1zd 304 10 in in IN cord-015569-vy49r1zd 304 11 genetically genetically RB cord-015569-vy49r1zd 304 12 hyperphagic hyperphagic JJ cord-015569-vy49r1zd 304 13 strain strain NN cord-015569-vy49r1zd 304 14 , , , cord-015569-vy49r1zd 304 15 db db NNP cord-015569-vy49r1zd 304 16 / / SYM cord-015569-vy49r1zd 304 17 db db NN cord-015569-vy49r1zd 304 18 ( ( -LRB- cord-015569-vy49r1zd 304 19 leptin leptin NNP cord-015569-vy49r1zd 304 20 receptor receptor NN cord-015569-vy49r1zd 304 21 gene gene NN cord-015569-vy49r1zd 304 22 deficiency deficiency NN cord-015569-vy49r1zd 304 23 ) ) -RRB- cord-015569-vy49r1zd 304 24 mice mouse NNS cord-015569-vy49r1zd 304 25 . . . cord-015569-vy49r1zd 305 1 These these DT cord-015569-vy49r1zd 305 2 results result NNS cord-015569-vy49r1zd 305 3 suggest suggest VBP cord-015569-vy49r1zd 305 4 that that IN cord-015569-vy49r1zd 305 5 taste taste VBP cord-015569-vy49r1zd 305 6 palatability palatability NN cord-015569-vy49r1zd 305 7 and/or and/or CC cord-015569-vy49r1zd 305 8 hedonics hedonic NNS cord-015569-vy49r1zd 305 9 of of IN cord-015569-vy49r1zd 305 10 sweeten sweeten NN cord-015569-vy49r1zd 305 11 food food NN cord-015569-vy49r1zd 305 12 play play VBP cord-015569-vy49r1zd 305 13 a a DT cord-015569-vy49r1zd 305 14 role role NN cord-015569-vy49r1zd 305 15 in in IN cord-015569-vy49r1zd 305 16 shifting shift VBG cord-015569-vy49r1zd 305 17 of of IN cord-015569-vy49r1zd 305 18 daily daily JJ cord-015569-vy49r1zd 305 19 feeding feeding NN cord-015569-vy49r1zd 305 20 rhythm rhythm NN cord-015569-vy49r1zd 305 21 . . . cord-015569-vy49r1zd 306 1 # # $ cord-015569-vy49r1zd 306 2 28 28 CD cord-015569-vy49r1zd 306 3 Sexual sexual JJ cord-015569-vy49r1zd 306 4 difference difference NN cord-015569-vy49r1zd 306 5 of of IN cord-015569-vy49r1zd 306 6 gene gene NN cord-015569-vy49r1zd 306 7 expression expression NN cord-015569-vy49r1zd 306 8 of of IN cord-015569-vy49r1zd 306 9 androgen androgen NN cord-015569-vy49r1zd 306 10 receptor receptor NN cord-015569-vy49r1zd 306 11 in in IN cord-015569-vy49r1zd 306 12 the the DT cord-015569-vy49r1zd 306 13 brain brain NN cord-015569-vy49r1zd 306 14 region region NN cord-015569-vy49r1zd 306 15 related relate VBN cord-015569-vy49r1zd 306 16 to to IN cord-015569-vy49r1zd 306 17 extinction extinction NN cord-015569-vy49r1zd 306 18 memory memory NN cord-015569-vy49r1zd 306 19 after after IN cord-015569-vy49r1zd 306 20 conditioned condition VBN cord-015569-vy49r1zd 306 21 taste taste NN cord-015569-vy49r1zd 306 22 aversion aversion NN cord-015569-vy49r1zd 306 23 learning learn VBG cord-015569-vy49r1zd 306 24 in in IN cord-015569-vy49r1zd 306 25 immature immature JJ cord-015569-vy49r1zd 306 26 mice mouse NNS cord-015569-vy49r1zd 307 1 Mice mouse NNS cord-015569-vy49r1zd 307 2 acquire acquire VBP cord-015569-vy49r1zd 307 3 the the DT cord-015569-vy49r1zd 307 4 conditioned condition VBN cord-015569-vy49r1zd 307 5 taste taste NN cord-015569-vy49r1zd 307 6 aversion aversion NN cord-015569-vy49r1zd 307 7 memory memory NN cord-015569-vy49r1zd 307 8 ( ( -LRB- cord-015569-vy49r1zd 307 9 CTAM CTAM NNP cord-015569-vy49r1zd 307 10 ) ) -RRB- cord-015569-vy49r1zd 307 11 by by IN cord-015569-vy49r1zd 307 12 application application NN cord-015569-vy49r1zd 307 13 of of IN cord-015569-vy49r1zd 307 14 the the DT cord-015569-vy49r1zd 307 15 conditioned condition VBN cord-015569-vy49r1zd 307 16 stimulus stimulus NN cord-015569-vy49r1zd 307 17 ( ( -LRB- cord-015569-vy49r1zd 307 18 CS CS NNP cord-015569-vy49r1zd 307 19 ) ) -RRB- cord-015569-vy49r1zd 307 20 such such JJ cord-015569-vy49r1zd 307 21 as as IN cord-015569-vy49r1zd 307 22 a a DT cord-015569-vy49r1zd 307 23 novel novel JJ cord-015569-vy49r1zd 307 24 taste taste NN cord-015569-vy49r1zd 307 25 , , , cord-015569-vy49r1zd 307 26 sodium sodium NN cord-015569-vy49r1zd 307 27 saccharin saccharin NN cord-015569-vy49r1zd 307 28 ( ( -LRB- cord-015569-vy49r1zd 307 29 Sac Sac NNP cord-015569-vy49r1zd 307 30 ) ) -RRB- cord-015569-vy49r1zd 307 31 , , , cord-015569-vy49r1zd 307 32 followed follow VBN cord-015569-vy49r1zd 307 33 by by IN cord-015569-vy49r1zd 307 34 the the DT cord-015569-vy49r1zd 307 35 unconditioned unconditioned JJ cord-015569-vy49r1zd 307 36 stimulus stimulus NN cord-015569-vy49r1zd 307 37 ( ( -LRB- cord-015569-vy49r1zd 307 38 US US NNP cord-015569-vy49r1zd 307 39 ) ) -RRB- cord-015569-vy49r1zd 307 40 such such JJ cord-015569-vy49r1zd 307 41 as as IN cord-015569-vy49r1zd 307 42 an an DT cord-015569-vy49r1zd 307 43 malaise malaise NN cord-015569-vy49r1zd 307 44 induced induce VBN cord-015569-vy49r1zd 307 45 by by IN cord-015569-vy49r1zd 307 46 an an DT cord-015569-vy49r1zd 307 47 i.p i.p NNP cord-015569-vy49r1zd 307 48 . . NNP cord-015569-vy49r1zd 307 49 injection injection NN cord-015569-vy49r1zd 307 50 of of IN cord-015569-vy49r1zd 307 51 LiCl LiCl NNP cord-015569-vy49r1zd 307 52 . . . cord-015569-vy49r1zd 308 1 After after IN cord-015569-vy49r1zd 308 2 conditioned condition VBN cord-015569-vy49r1zd 308 3 taste taste NN cord-015569-vy49r1zd 308 4 aversion aversion NN cord-015569-vy49r1zd 308 5 ( ( -LRB- cord-015569-vy49r1zd 308 6 CTA CTA NNP cord-015569-vy49r1zd 308 7 ) ) -RRB- cord-015569-vy49r1zd 308 8 learning learning NN cord-015569-vy49r1zd 308 9 , , , cord-015569-vy49r1zd 308 10 the the DT cord-015569-vy49r1zd 308 11 extinction extinction NN cord-015569-vy49r1zd 308 12 of of IN cord-015569-vy49r1zd 308 13 CTAM CTAM NNP cord-015569-vy49r1zd 308 14 is be VBZ cord-015569-vy49r1zd 308 15 induced induce VBN cord-015569-vy49r1zd 308 16 by by IN cord-015569-vy49r1zd 308 17 repeated repeat VBN cord-015569-vy49r1zd 308 18 presentations presentation NNS cord-015569-vy49r1zd 308 19 of of IN cord-015569-vy49r1zd 308 20 CS CS NNP cord-015569-vy49r1zd 308 21 without without IN cord-015569-vy49r1zd 308 22 US US NNP cord-015569-vy49r1zd 308 23 . . . cord-015569-vy49r1zd 309 1 Recent recent JJ cord-015569-vy49r1zd 309 2 studies study NNS cord-015569-vy49r1zd 309 3 have have VBP cord-015569-vy49r1zd 309 4 demonstrated demonstrate VBN cord-015569-vy49r1zd 309 5 that that IN cord-015569-vy49r1zd 309 6 the the DT cord-015569-vy49r1zd 309 7 extinction extinction NN cord-015569-vy49r1zd 309 8 is be VBZ cord-015569-vy49r1zd 309 9 a a DT cord-015569-vy49r1zd 309 10 process process NN cord-015569-vy49r1zd 309 11 of of IN cord-015569-vy49r1zd 309 12 relearning relearning NN cord-015569-vy49r1zd 309 13 , , , cord-015569-vy49r1zd 309 14 where where WRB cord-015569-vy49r1zd 309 15 mice mouse NNS cord-015569-vy49r1zd 309 16 acquire acquire VBP cord-015569-vy49r1zd 309 17 the the DT cord-015569-vy49r1zd 309 18 extinction extinction NN cord-015569-vy49r1zd 309 19 memory memory NN cord-015569-vy49r1zd 309 20 of of IN cord-015569-vy49r1zd 309 21 CTA CTA NNP cord-015569-vy49r1zd 309 22 . . . cord-015569-vy49r1zd 310 1 We -PRON- PRP cord-015569-vy49r1zd 310 2 have have VBP cord-015569-vy49r1zd 310 3 reported report VBN cord-015569-vy49r1zd 310 4 that that IN cord-015569-vy49r1zd 310 5 the the DT cord-015569-vy49r1zd 310 6 sexually sexually RB cord-015569-vy49r1zd 310 7 mature mature JJ cord-015569-vy49r1zd 310 8 male male JJ cord-015569-vy49r1zd 310 9 mice mouse NNS cord-015569-vy49r1zd 310 10 ( ( -LRB- cord-015569-vy49r1zd 310 11 C57BL/6 C57BL/6 NNP cord-015569-vy49r1zd 310 12 ) ) -RRB- cord-015569-vy49r1zd 310 13 represented represent VBD cord-015569-vy49r1zd 310 14 significantly significantly RB cord-015569-vy49r1zd 310 15 higher high JJR cord-015569-vy49r1zd 310 16 retention retention NN cord-015569-vy49r1zd 310 17 of of IN cord-015569-vy49r1zd 310 18 extinction extinction NN cord-015569-vy49r1zd 310 19 memory memory NN cord-015569-vy49r1zd 310 20 ( ( -LRB- cord-015569-vy49r1zd 310 21 REM rem NN cord-015569-vy49r1zd 310 22 ) ) -RRB- cord-015569-vy49r1zd 310 23 than than IN cord-015569-vy49r1zd 310 24 sexually sexually RB cord-015569-vy49r1zd 310 25 immature immature JJ cord-015569-vy49r1zd 310 26 male male JJ cord-015569-vy49r1zd 310 27 mice mouse NNS cord-015569-vy49r1zd 310 28 . . . cord-015569-vy49r1zd 311 1 In in IN cord-015569-vy49r1zd 311 2 contrast contrast NN cord-015569-vy49r1zd 311 3 , , , cord-015569-vy49r1zd 311 4 the the DT cord-015569-vy49r1zd 311 5 significant significant JJ cord-015569-vy49r1zd 311 6 difference difference NN cord-015569-vy49r1zd 311 7 was be VBD cord-015569-vy49r1zd 311 8 not not RB cord-015569-vy49r1zd 311 9 observed observe VBN cord-015569-vy49r1zd 311 10 in in IN cord-015569-vy49r1zd 311 11 female female JJ cord-015569-vy49r1zd 311 12 mice mouse NNS cord-015569-vy49r1zd 311 13 . . . cord-015569-vy49r1zd 312 1 We -PRON- PRP cord-015569-vy49r1zd 312 2 have have VBP cord-015569-vy49r1zd 312 3 also also RB cord-015569-vy49r1zd 312 4 reported report VBN cord-015569-vy49r1zd 312 5 that that IN cord-015569-vy49r1zd 312 6 chronical chronical JJ cord-015569-vy49r1zd 312 7 administration administration NN cord-015569-vy49r1zd 312 8 of of IN cord-015569-vy49r1zd 312 9 androgen androgen NN cord-015569-vy49r1zd 312 10 into into IN cord-015569-vy49r1zd 312 11 castrated castrate VBN cord-015569-vy49r1zd 312 12 mice mouse NNS cord-015569-vy49r1zd 312 13 during during IN cord-015569-vy49r1zd 312 14 prematuration prematuration NN cord-015569-vy49r1zd 312 15 period period NN cord-015569-vy49r1zd 312 16 results result VBZ cord-015569-vy49r1zd 312 17 in in IN cord-015569-vy49r1zd 312 18 an an DT cord-015569-vy49r1zd 312 19 enhancement enhancement NN cord-015569-vy49r1zd 312 20 of of IN cord-015569-vy49r1zd 312 21 REM rem NN cord-015569-vy49r1zd 312 22 in in IN cord-015569-vy49r1zd 312 23 both both DT cord-015569-vy49r1zd 312 24 sexes sex NNS cord-015569-vy49r1zd 312 25 . . . cord-015569-vy49r1zd 313 1 Here here RB cord-015569-vy49r1zd 313 2 we -PRON- PRP cord-015569-vy49r1zd 313 3 investigated investigate VBD cord-015569-vy49r1zd 313 4 whether whether IN cord-015569-vy49r1zd 313 5 the the DT cord-015569-vy49r1zd 313 6 sex sex NN cord-015569-vy49r1zd 313 7 difference difference NN cord-015569-vy49r1zd 313 8 of of IN cord-015569-vy49r1zd 313 9 the the DT cord-015569-vy49r1zd 313 10 gene gene NN cord-015569-vy49r1zd 313 11 expression expression NN cord-015569-vy49r1zd 313 12 of of IN cord-015569-vy49r1zd 313 13 androgen androgen NN cord-015569-vy49r1zd 313 14 receptor receptor NN cord-015569-vy49r1zd 313 15 ( ( -LRB- cord-015569-vy49r1zd 313 16 AR AR NNP cord-015569-vy49r1zd 313 17 ) ) -RRB- cord-015569-vy49r1zd 313 18 is be VBZ cord-015569-vy49r1zd 313 19 observed observe VBN cord-015569-vy49r1zd 313 20 in in IN cord-015569-vy49r1zd 313 21 the the DT cord-015569-vy49r1zd 313 22 ventral ventral JJ cord-015569-vy49r1zd 313 23 medial medial JJ cord-015569-vy49r1zd 313 24 prefrontal prefrontal JJ cord-015569-vy49r1zd 313 25 cortex cortex NN cord-015569-vy49r1zd 313 26 ( ( -LRB- cord-015569-vy49r1zd 313 27 vmPFC vmPFC NNP cord-015569-vy49r1zd 313 28 ) ) -RRB- cord-015569-vy49r1zd 313 29 and and CC cord-015569-vy49r1zd 313 30 amygdala amygdala NN cord-015569-vy49r1zd 313 31 between between IN cord-015569-vy49r1zd 313 32 sexually sexually RB cord-015569-vy49r1zd 313 33 immature immature JJ cord-015569-vy49r1zd 313 34 and and CC cord-015569-vy49r1zd 313 35 mature mature JJ cord-015569-vy49r1zd 313 36 mice mouse NNS cord-015569-vy49r1zd 313 37 by by IN cord-015569-vy49r1zd 313 38 real real JJ cord-015569-vy49r1zd 313 39 - - HYPH cord-015569-vy49r1zd 313 40 time time NN cord-015569-vy49r1zd 313 41 PCR PCR NNP cord-015569-vy49r1zd 313 42 . . . cord-015569-vy49r1zd 314 1 The the DT cord-015569-vy49r1zd 314 2 sexually sexually RB cord-015569-vy49r1zd 314 3 immature immature JJ cord-015569-vy49r1zd 314 4 male male JJ cord-015569-vy49r1zd 314 5 mice mouse NNS cord-015569-vy49r1zd 314 6 presented present VBN cord-015569-vy49r1zd 314 7 significantly significantly RB cord-015569-vy49r1zd 314 8 higher high JJR cord-015569-vy49r1zd 314 9 level level NN cord-015569-vy49r1zd 314 10 of of IN cord-015569-vy49r1zd 314 11 AR AR NNP cord-015569-vy49r1zd 314 12 gene gene NN cord-015569-vy49r1zd 314 13 in in IN cord-015569-vy49r1zd 314 14 vmPFC vmPFC NNS cord-015569-vy49r1zd 314 15 and and CC cord-015569-vy49r1zd 314 16 amygdala amygdala NN cord-015569-vy49r1zd 314 17 than than IN cord-015569-vy49r1zd 314 18 the the DT cord-015569-vy49r1zd 314 19 sexually sexually RB cord-015569-vy49r1zd 314 20 mature mature JJ cord-015569-vy49r1zd 314 21 male male JJ cord-015569-vy49r1zd 314 22 mice mouse NNS cord-015569-vy49r1zd 314 23 . . . cord-015569-vy49r1zd 315 1 However however RB cord-015569-vy49r1zd 315 2 , , , cord-015569-vy49r1zd 315 3 there there EX cord-015569-vy49r1zd 315 4 was be VBD cord-015569-vy49r1zd 315 5 no no DT cord-015569-vy49r1zd 315 6 such such JJ cord-015569-vy49r1zd 315 7 difference difference NN cord-015569-vy49r1zd 315 8 in in IN cord-015569-vy49r1zd 315 9 vmPFC vmPFC NNS cord-015569-vy49r1zd 315 10 and and CC cord-015569-vy49r1zd 315 11 amygdala amygdala NN cord-015569-vy49r1zd 315 12 of of IN cord-015569-vy49r1zd 315 13 the the DT cord-015569-vy49r1zd 315 14 female female JJ cord-015569-vy49r1zd 315 15 mice mouse NNS cord-015569-vy49r1zd 315 16 . . . cord-015569-vy49r1zd 316 1 These these DT cord-015569-vy49r1zd 316 2 results result NNS cord-015569-vy49r1zd 316 3 suggest suggest VBP cord-015569-vy49r1zd 316 4 that that IN cord-015569-vy49r1zd 316 5 the the DT cord-015569-vy49r1zd 316 6 sex sex NN cord-015569-vy49r1zd 316 7 difference difference NN cord-015569-vy49r1zd 316 8 in in IN cord-015569-vy49r1zd 316 9 maturation maturation NN cord-015569-vy49r1zd 316 10 process process NN cord-015569-vy49r1zd 316 11 of of IN cord-015569-vy49r1zd 316 12 REM rem NN cord-015569-vy49r1zd 316 13 is be VBZ cord-015569-vy49r1zd 316 14 induced induce VBN cord-015569-vy49r1zd 316 15 by by IN cord-015569-vy49r1zd 316 16 androgen androgen NN cord-015569-vy49r1zd 316 17 acting act VBG cord-015569-vy49r1zd 316 18 on on IN cord-015569-vy49r1zd 316 19 vmPFC vmPFC NNS cord-015569-vy49r1zd 316 20 and and CC cord-015569-vy49r1zd 316 21 amygdala amygdala NN cord-015569-vy49r1zd 316 22 during during IN cord-015569-vy49r1zd 316 23 sexual sexual JJ cord-015569-vy49r1zd 316 24 prematuration prematuration NN cord-015569-vy49r1zd 316 25 period period NN cord-015569-vy49r1zd 316 26 in in IN cord-015569-vy49r1zd 316 27 mice mouse NNS cord-015569-vy49r1zd 316 28 . . . cord-015569-vy49r1zd 317 1 Our -PRON- PRP$ cord-015569-vy49r1zd 317 2 previous previous JJ cord-015569-vy49r1zd 317 3 study study NN cord-015569-vy49r1zd 317 4 showed show VBD cord-015569-vy49r1zd 317 5 that that IN cord-015569-vy49r1zd 317 6 weanling weanle VBG cord-015569-vy49r1zd 317 7 rats rat NNS cord-015569-vy49r1zd 317 8 acquired acquire VBD cord-015569-vy49r1zd 317 9 conditioned condition VBN cord-015569-vy49r1zd 317 10 flavor flavor NN cord-015569-vy49r1zd 317 11 preference preference NN cord-015569-vy49r1zd 317 12 when when WRB cord-015569-vy49r1zd 317 13 the the DT cord-015569-vy49r1zd 317 14 flavor flavor NN cord-015569-vy49r1zd 317 15 was be VBD cord-015569-vy49r1zd 317 16 associated associate VBN cord-015569-vy49r1zd 317 17 with with IN cord-015569-vy49r1zd 317 18 low low JJ cord-015569-vy49r1zd 317 19 concentration concentration NN cord-015569-vy49r1zd 317 20 of of IN cord-015569-vy49r1zd 317 21 sucrose sucrose NN cord-015569-vy49r1zd 317 22 ; ; : cord-015569-vy49r1zd 317 23 while while IN cord-015569-vy49r1zd 317 24 flavor flavor NN cord-015569-vy49r1zd 317 25 aversion aversion NN cord-015569-vy49r1zd 317 26 when when WRB cord-015569-vy49r1zd 317 27 associated associate VBN cord-015569-vy49r1zd 317 28 with with IN cord-015569-vy49r1zd 317 29 high high JJ cord-015569-vy49r1zd 317 30 concentration concentration NN cord-015569-vy49r1zd 317 31 . . . cord-015569-vy49r1zd 318 1 The the DT cord-015569-vy49r1zd 318 2 present present JJ cord-015569-vy49r1zd 318 3 study study NN cord-015569-vy49r1zd 318 4 aims aim VBZ cord-015569-vy49r1zd 318 5 to to TO cord-015569-vy49r1zd 318 6 confirm confirm VB cord-015569-vy49r1zd 318 7 and and CC cord-015569-vy49r1zd 318 8 extend extend VB cord-015569-vy49r1zd 318 9 this this DT cord-015569-vy49r1zd 318 10 finding finding NN cord-015569-vy49r1zd 318 11 with with IN cord-015569-vy49r1zd 318 12 various various JJ cord-015569-vy49r1zd 318 13 concentrations concentration NNS cord-015569-vy49r1zd 318 14 of of IN cord-015569-vy49r1zd 318 15 sucrose sucrose NN cord-015569-vy49r1zd 318 16 . . . cord-015569-vy49r1zd 319 1 Wister Wister NNP cord-015569-vy49r1zd 319 2 male male JJ cord-015569-vy49r1zd 319 3 3-week 3-week JJ cord-015569-vy49r1zd 319 4 - - HYPH cord-015569-vy49r1zd 319 5 old old JJ cord-015569-vy49r1zd 319 6 rats rat NNS cord-015569-vy49r1zd 319 7 were be VBD cord-015569-vy49r1zd 319 8 used use VBN cord-015569-vy49r1zd 319 9 . . . cord-015569-vy49r1zd 320 1 Half half NN cord-015569-vy49r1zd 320 2 of of IN cord-015569-vy49r1zd 320 3 the the DT cord-015569-vy49r1zd 320 4 rats rat NNS cord-015569-vy49r1zd 320 5 received receive VBD cord-015569-vy49r1zd 320 6 unsweetened unsweetened JJ cord-015569-vy49r1zd 320 7 grape grape NN cord-015569-vy49r1zd 320 8 - - HYPH cord-015569-vy49r1zd 320 9 flavored flavor VBN cord-015569-vy49r1zd 320 10 water water NN cord-015569-vy49r1zd 320 11 on on IN cord-015569-vy49r1zd 320 12 odd odd RB cord-015569-vy49r1zd 320 13 - - HYPH cord-015569-vy49r1zd 320 14 numbered number VBN cord-015569-vy49r1zd 320 15 days day NNS cord-015569-vy49r1zd 320 16 and and CC cord-015569-vy49r1zd 320 17 sweetened sweeten VBN cord-015569-vy49r1zd 320 18 ( ( -LRB- cord-015569-vy49r1zd 320 19 sucrose sucrose NN cord-015569-vy49r1zd 320 20 ) ) -RRB- cord-015569-vy49r1zd 320 21 cherry cherry NN cord-015569-vy49r1zd 320 22 - - HYPH cord-015569-vy49r1zd 320 23 flavored flavor VBN cord-015569-vy49r1zd 320 24 solution solution NN cord-015569-vy49r1zd 320 25 on on IN cord-015569-vy49r1zd 320 26 even even RB cord-015569-vy49r1zd 320 27 - - HYPH cord-015569-vy49r1zd 320 28 numbered number VBN cord-015569-vy49r1zd 320 29 days day NNS cord-015569-vy49r1zd 320 30 . . . cord-015569-vy49r1zd 321 1 The the DT cord-015569-vy49r1zd 321 2 remaining remain VBG cord-015569-vy49r1zd 321 3 rats rat NNS cord-015569-vy49r1zd 321 4 received receive VBD cord-015569-vy49r1zd 321 5 sweetened sweeten VBN cord-015569-vy49r1zd 321 6 grape grape NN cord-015569-vy49r1zd 321 7 - - HYPH cord-015569-vy49r1zd 321 8 flavored flavor VBN cord-015569-vy49r1zd 321 9 solution solution NN cord-015569-vy49r1zd 321 10 on on IN cord-015569-vy49r1zd 321 11 odd odd RB cord-015569-vy49r1zd 321 12 - - HYPH cord-015569-vy49r1zd 321 13 numbered number VBN cord-015569-vy49r1zd 321 14 days day NNS cord-015569-vy49r1zd 321 15 and and CC cord-015569-vy49r1zd 321 16 unsweetened unsweetened JJ cord-015569-vy49r1zd 321 17 cherry cherry NN cord-015569-vy49r1zd 321 18 - - HYPH cord-015569-vy49r1zd 321 19 flavored flavor VBN cord-015569-vy49r1zd 321 20 water water NN cord-015569-vy49r1zd 321 21 on on IN cord-015569-vy49r1zd 321 22 even even RB cord-015569-vy49r1zd 321 23 - - HYPH cord-015569-vy49r1zd 321 24 numbered number VBN cord-015569-vy49r1zd 321 25 days day NNS cord-015569-vy49r1zd 321 26 . . . cord-015569-vy49r1zd 322 1 During during IN cord-015569-vy49r1zd 322 2 the the DT cord-015569-vy49r1zd 322 3 acquisition acquisition NN cord-015569-vy49r1zd 322 4 session session NN cord-015569-vy49r1zd 322 5 , , , cord-015569-vy49r1zd 322 6 the the DT cord-015569-vy49r1zd 322 7 liquid liquid NN cord-015569-vy49r1zd 322 8 was be VBD cord-015569-vy49r1zd 322 9 presented present VBN cord-015569-vy49r1zd 322 10 to to IN cord-015569-vy49r1zd 322 11 each each DT cord-015569-vy49r1zd 322 12 rat rat NN cord-015569-vy49r1zd 322 13 for for IN cord-015569-vy49r1zd 322 14 15 15 CD cord-015569-vy49r1zd 322 15 min min NN cord-015569-vy49r1zd 322 16 daily daily RB cord-015569-vy49r1zd 322 17 across across IN cord-015569-vy49r1zd 322 18 6 6 CD cord-015569-vy49r1zd 322 19 consecutive consecutive JJ cord-015569-vy49r1zd 322 20 days day NNS cord-015569-vy49r1zd 322 21 . . . cord-015569-vy49r1zd 323 1 In in IN cord-015569-vy49r1zd 323 2 the the DT cord-015569-vy49r1zd 323 3 following following JJ cord-015569-vy49r1zd 323 4 test test NN cord-015569-vy49r1zd 323 5 session session NN cord-015569-vy49r1zd 323 6 , , , cord-015569-vy49r1zd 323 7 each each DT cord-015569-vy49r1zd 323 8 rat rat NN cord-015569-vy49r1zd 323 9 was be VBD cord-015569-vy49r1zd 323 10 presented present VBN cord-015569-vy49r1zd 323 11 with with IN cord-015569-vy49r1zd 323 12 unsweetened unsweetened JJ cord-015569-vy49r1zd 323 13 cherry cherry NN cord-015569-vy49r1zd 323 14 - - HYPH cord-015569-vy49r1zd 323 15 and and CC cord-015569-vy49r1zd 323 16 grape grape NN cord-015569-vy49r1zd 323 17 - - HYPH cord-015569-vy49r1zd 323 18 flavored flavor VBN cord-015569-vy49r1zd 323 19 water water NN cord-015569-vy49r1zd 323 20 simultaneously simultaneously RB cord-015569-vy49r1zd 323 21 for for IN cord-015569-vy49r1zd 323 22 15 15 CD cord-015569-vy49r1zd 323 23 min min NN cord-015569-vy49r1zd 323 24 daily daily RB cord-015569-vy49r1zd 323 25 across across IN cord-015569-vy49r1zd 323 26 4 4 CD cord-015569-vy49r1zd 323 27 consecutive consecutive JJ cord-015569-vy49r1zd 323 28 days day NNS cord-015569-vy49r1zd 323 29 . . . cord-015569-vy49r1zd 324 1 The the DT cord-015569-vy49r1zd 324 2 rats rat NNS cord-015569-vy49r1zd 324 3 showed show VBD cord-015569-vy49r1zd 324 4 a a DT cord-015569-vy49r1zd 324 5 significant significant JJ cord-015569-vy49r1zd 324 6 preference preference NN cord-015569-vy49r1zd 324 7 for for IN cord-015569-vy49r1zd 324 8 the the DT cord-015569-vy49r1zd 324 9 flavor flavor NN cord-015569-vy49r1zd 324 10 associated associate VBN cord-015569-vy49r1zd 324 11 with with IN cord-015569-vy49r1zd 324 12 2 2 CD cord-015569-vy49r1zd 324 13 % % NN cord-015569-vy49r1zd 324 14 or or CC cord-015569-vy49r1zd 324 15 10 10 CD cord-015569-vy49r1zd 324 16 % % NN cord-015569-vy49r1zd 324 17 sucrose sucrose NN cord-015569-vy49r1zd 324 18 , , , cord-015569-vy49r1zd 324 19 but but CC cord-015569-vy49r1zd 324 20 showed show VBD cord-015569-vy49r1zd 324 21 a a DT cord-015569-vy49r1zd 324 22 significant significant JJ cord-015569-vy49r1zd 324 23 aversion aversion NN cord-015569-vy49r1zd 324 24 to to IN cord-015569-vy49r1zd 324 25 the the DT cord-015569-vy49r1zd 324 26 flavor flavor NN cord-015569-vy49r1zd 324 27 associated associate VBN cord-015569-vy49r1zd 324 28 with with IN cord-015569-vy49r1zd 324 29 30 30 CD cord-015569-vy49r1zd 324 30 % % NN cord-015569-vy49r1zd 324 31 sucrose sucrose NN cord-015569-vy49r1zd 324 32 , , , cord-015569-vy49r1zd 324 33 suggesting suggest VBG cord-015569-vy49r1zd 324 34 a a DT cord-015569-vy49r1zd 324 35 hedonic hedonic JJ cord-015569-vy49r1zd 324 36 shift shift NN cord-015569-vy49r1zd 324 37 from from IN cord-015569-vy49r1zd 324 38 positive positive JJ cord-015569-vy49r1zd 324 39 to to IN cord-015569-vy49r1zd 324 40 negative negative JJ cord-015569-vy49r1zd 324 41 with with IN cord-015569-vy49r1zd 324 42 increasing increase VBG cord-015569-vy49r1zd 324 43 the the DT cord-015569-vy49r1zd 324 44 concentration concentration NN cord-015569-vy49r1zd 324 45 . . . cord-015569-vy49r1zd 325 1 The the DT cord-015569-vy49r1zd 325 2 association association NN cord-015569-vy49r1zd 325 3 learning learning NN cord-015569-vy49r1zd 325 4 acquired acquire VBD cord-015569-vy49r1zd 325 5 at at IN cord-015569-vy49r1zd 325 6 the the DT cord-015569-vy49r1zd 325 7 age age NN cord-015569-vy49r1zd 325 8 of of IN cord-015569-vy49r1zd 325 9 3 3 CD cord-015569-vy49r1zd 325 10 weeks week NNS cord-015569-vy49r1zd 325 11 was be VBD cord-015569-vy49r1zd 325 12 preserved preserve VBN cord-015569-vy49r1zd 325 13 when when WRB cord-015569-vy49r1zd 325 14 retested reteste VBN cord-015569-vy49r1zd 325 15 at at IN cord-015569-vy49r1zd 325 16 the the DT cord-015569-vy49r1zd 325 17 age age NN cord-015569-vy49r1zd 325 18 of of IN cord-015569-vy49r1zd 325 19 20 20 CD cord-015569-vy49r1zd 325 20 weeks week NNS cord-015569-vy49r1zd 325 21 . . . cord-015569-vy49r1zd 326 1 Short short JJ cord-015569-vy49r1zd 326 2 - - HYPH cord-015569-vy49r1zd 326 3 term term NN cord-015569-vy49r1zd 326 4 ( ( -LRB- cord-015569-vy49r1zd 326 5 5 5 CD cord-015569-vy49r1zd 326 6 min min NN cord-015569-vy49r1zd 326 7 ) ) -RRB- cord-015569-vy49r1zd 326 8 drinking drinking NN cord-015569-vy49r1zd 326 9 test test NN cord-015569-vy49r1zd 326 10 showed show VBD cord-015569-vy49r1zd 326 11 that that IN cord-015569-vy49r1zd 326 12 the the DT cord-015569-vy49r1zd 326 13 volume volume NN cord-015569-vy49r1zd 326 14 of of IN cord-015569-vy49r1zd 326 15 intake intake NN cord-015569-vy49r1zd 326 16 was be VBD cord-015569-vy49r1zd 326 17 significantly significantly RB cord-015569-vy49r1zd 326 18 smaller small JJR cord-015569-vy49r1zd 326 19 for for IN cord-015569-vy49r1zd 326 20 30 30 CD cord-015569-vy49r1zd 326 21 % % NN cord-015569-vy49r1zd 326 22 than than IN cord-015569-vy49r1zd 326 23 for for IN cord-015569-vy49r1zd 326 24 2 2 CD cord-015569-vy49r1zd 326 25 % % NN cord-015569-vy49r1zd 326 26 and and CC cord-015569-vy49r1zd 326 27 20 20 CD cord-015569-vy49r1zd 326 28 % % NN cord-015569-vy49r1zd 326 29 sucrose sucrose NN cord-015569-vy49r1zd 326 30 , , , cord-015569-vy49r1zd 326 31 indicating indicate VBG cord-015569-vy49r1zd 326 32 that that IN cord-015569-vy49r1zd 326 33 30 30 CD cord-015569-vy49r1zd 326 34 % % NN cord-015569-vy49r1zd 326 35 sucrose sucrose NN cord-015569-vy49r1zd 326 36 is be VBZ cord-015569-vy49r1zd 326 37 aversive aversive JJ cord-015569-vy49r1zd 326 38 because because IN cord-015569-vy49r1zd 326 39 of of IN cord-015569-vy49r1zd 326 40 its -PRON- PRP$ cord-015569-vy49r1zd 326 41 oropharyngeal oropharyngeal JJ cord-015569-vy49r1zd 326 42 sensation sensation NN cord-015569-vy49r1zd 326 43 rather rather RB cord-015569-vy49r1zd 326 44 than than IN cord-015569-vy49r1zd 326 45 its -PRON- PRP$ cord-015569-vy49r1zd 326 46 post post JJ cord-015569-vy49r1zd 326 47 - - JJ cord-015569-vy49r1zd 326 48 ingestive ingestive JJ cord-015569-vy49r1zd 326 49 effects effect NNS cord-015569-vy49r1zd 326 50 . . . cord-015569-vy49r1zd 327 1 The the DT cord-015569-vy49r1zd 327 2 present present JJ cord-015569-vy49r1zd 327 3 study study NN cord-015569-vy49r1zd 327 4 suggests suggest VBZ cord-015569-vy49r1zd 327 5 that that IN cord-015569-vy49r1zd 327 6 weanling weanle VBG cord-015569-vy49r1zd 327 7 experience experience NN cord-015569-vy49r1zd 327 8 of of IN cord-015569-vy49r1zd 327 9 food food NN cord-015569-vy49r1zd 327 10 is be VBZ cord-015569-vy49r1zd 327 11 important important JJ cord-015569-vy49r1zd 327 12 in in IN cord-015569-vy49r1zd 327 13 the the DT cord-015569-vy49r1zd 327 14 formation formation NN cord-015569-vy49r1zd 327 15 of of IN cord-015569-vy49r1zd 327 16 feeding feed VBG cord-015569-vy49r1zd 327 17 behavior behavior NN cord-015569-vy49r1zd 327 18 in in IN cord-015569-vy49r1zd 327 19 adulthood adulthood NN cord-015569-vy49r1zd 327 20 . . . cord-015569-vy49r1zd 328 1 Tastes taste NNS cord-015569-vy49r1zd 328 2 play play VBP cord-015569-vy49r1zd 328 3 important important JJ cord-015569-vy49r1zd 328 4 roles role NNS cord-015569-vy49r1zd 328 5 in in IN cord-015569-vy49r1zd 328 6 detecting detect VBG cord-015569-vy49r1zd 328 7 nutrients nutrient NNS cord-015569-vy49r1zd 328 8 and and CC cord-015569-vy49r1zd 328 9 irritant irritant JJ cord-015569-vy49r1zd 328 10 materials material NNS cord-015569-vy49r1zd 328 11 in in IN cord-015569-vy49r1zd 328 12 food food NN cord-015569-vy49r1zd 328 13 . . . cord-015569-vy49r1zd 329 1 Preference preference NN cord-015569-vy49r1zd 329 2 for for IN cord-015569-vy49r1zd 329 3 food food NN cord-015569-vy49r1zd 329 4 tastes taste NNS cord-015569-vy49r1zd 329 5 is be VBZ cord-015569-vy49r1zd 329 6 critical critical JJ cord-015569-vy49r1zd 329 7 for for IN cord-015569-vy49r1zd 329 8 ingestive ingestive JJ cord-015569-vy49r1zd 329 9 behavior behavior NN cord-015569-vy49r1zd 329 10 because because IN cord-015569-vy49r1zd 329 11 greater great JJR cord-015569-vy49r1zd 329 12 palatability palatability NN cord-015569-vy49r1zd 329 13 is be VBZ cord-015569-vy49r1zd 329 14 to to TO cord-015569-vy49r1zd 329 15 evoke evoke VB cord-015569-vy49r1zd 329 16 greater great JJR cord-015569-vy49r1zd 329 17 food food NN cord-015569-vy49r1zd 329 18 intake intake NN cord-015569-vy49r1zd 329 19 . . . cord-015569-vy49r1zd 330 1 Animals animal NNS cord-015569-vy49r1zd 330 2 generally generally RB cord-015569-vy49r1zd 330 3 prefer prefer VBP cord-015569-vy49r1zd 330 4 sweetness sweetness NN cord-015569-vy49r1zd 330 5 but but CC cord-015569-vy49r1zd 330 6 not not RB cord-015569-vy49r1zd 330 7 bitterness bitterness NN cord-015569-vy49r1zd 330 8 . . . cord-015569-vy49r1zd 331 1 Such such JJ cord-015569-vy49r1zd 331 2 taste taste NN cord-015569-vy49r1zd 331 3 preferences preference NNS cord-015569-vy49r1zd 331 4 are be VBP cord-015569-vy49r1zd 331 5 known know VBN cord-015569-vy49r1zd 331 6 to to TO cord-015569-vy49r1zd 331 7 be be VB cord-015569-vy49r1zd 331 8 affected affect VBN cord-015569-vy49r1zd 331 9 by by IN cord-015569-vy49r1zd 331 10 aging age VBG cord-015569-vy49r1zd 331 11 which which WDT cord-015569-vy49r1zd 331 12 causes cause VBZ cord-015569-vy49r1zd 331 13 changes change NNS cord-015569-vy49r1zd 331 14 in in IN cord-015569-vy49r1zd 331 15 the the DT cord-015569-vy49r1zd 331 16 dietary dietary JJ cord-015569-vy49r1zd 331 17 and and CC cord-015569-vy49r1zd 331 18 energy energy NN cord-015569-vy49r1zd 331 19 requirements requirement NNS cord-015569-vy49r1zd 331 20 . . . cord-015569-vy49r1zd 332 1 However however RB cord-015569-vy49r1zd 332 2 , , , cord-015569-vy49r1zd 332 3 the the DT cord-015569-vy49r1zd 332 4 mechanisms mechanism NNS cord-015569-vy49r1zd 332 5 of of IN cord-015569-vy49r1zd 332 6 shift shift NN cord-015569-vy49r1zd 332 7 in in IN cord-015569-vy49r1zd 332 8 taste taste NN cord-015569-vy49r1zd 332 9 preference preference NN cord-015569-vy49r1zd 332 10 by by IN cord-015569-vy49r1zd 332 11 aging age VBG cord-015569-vy49r1zd 332 12 still still RB cord-015569-vy49r1zd 332 13 remain remain VBP cord-015569-vy49r1zd 332 14 unclear unclear JJ cord-015569-vy49r1zd 332 15 . . . cord-015569-vy49r1zd 333 1 Therefore therefore RB cord-015569-vy49r1zd 333 2 , , , cord-015569-vy49r1zd 333 3 to to TO cord-015569-vy49r1zd 333 4 elucidate elucidate VB cord-015569-vy49r1zd 333 5 differences difference NNS cord-015569-vy49r1zd 333 6 in in IN cord-015569-vy49r1zd 333 7 taste taste NN cord-015569-vy49r1zd 333 8 preference preference NN cord-015569-vy49r1zd 333 9 among among IN cord-015569-vy49r1zd 333 10 the the DT cord-015569-vy49r1zd 333 11 life life NN cord-015569-vy49r1zd 333 12 stages stage NNS cord-015569-vy49r1zd 333 13 , , , cord-015569-vy49r1zd 333 14 we -PRON- PRP cord-015569-vy49r1zd 333 15 measured measure VBD cord-015569-vy49r1zd 333 16 the the DT cord-015569-vy49r1zd 333 17 amount amount NN cord-015569-vy49r1zd 333 18 of of IN cord-015569-vy49r1zd 333 19 intake intake NN cord-015569-vy49r1zd 333 20 of of IN cord-015569-vy49r1zd 333 21 taste taste NN cord-015569-vy49r1zd 333 22 solutions solution NNS cord-015569-vy49r1zd 333 23 by by IN cord-015569-vy49r1zd 333 24 the the DT cord-015569-vy49r1zd 333 25 two two CD cord-015569-vy49r1zd 333 26 bottle bottle NN cord-015569-vy49r1zd 333 27 test test NN cord-015569-vy49r1zd 333 28 . . . cord-015569-vy49r1zd 334 1 We -PRON- PRP cord-015569-vy49r1zd 334 2 used use VBD cord-015569-vy49r1zd 334 3 juvenile juvenile JJ cord-015569-vy49r1zd 334 4 ( ( -LRB- cord-015569-vy49r1zd 334 5 3 3 CD cord-015569-vy49r1zd 334 6 - - SYM cord-015569-vy49r1zd 334 7 6 6 CD cord-015569-vy49r1zd 334 8 weeks week NNS cord-015569-vy49r1zd 334 9 ) ) -RRB- cord-015569-vy49r1zd 334 10 , , , cord-015569-vy49r1zd 334 11 young young JJ cord-015569-vy49r1zd 334 12 - - HYPH cord-015569-vy49r1zd 334 13 adult adult NN cord-015569-vy49r1zd 334 14 ( ( -LRB- cord-015569-vy49r1zd 334 15 8 8 CD cord-015569-vy49r1zd 334 16 - - SYM cord-015569-vy49r1zd 334 17 11 11 CD cord-015569-vy49r1zd 334 18 weeks week NNS cord-015569-vy49r1zd 334 19 ) ) -RRB- cord-015569-vy49r1zd 334 20 , , , cord-015569-vy49r1zd 334 21 adult adult NN cord-015569-vy49r1zd 334 22 ( ( -LRB- cord-015569-vy49r1zd 334 23 17 17 CD cord-015569-vy49r1zd 334 24 - - SYM cord-015569-vy49r1zd 334 25 20 20 CD cord-015569-vy49r1zd 334 26 weeks week NNS cord-015569-vy49r1zd 334 27 ) ) -RRB- cord-015569-vy49r1zd 334 28 , , , cord-015569-vy49r1zd 334 29 and and CC cord-015569-vy49r1zd 334 30 middle middle NN cord-015569-vy49r1zd 334 31 - - HYPH cord-015569-vy49r1zd 334 32 aged aged JJ cord-015569-vy49r1zd 334 33 ( ( -LRB- cord-015569-vy49r1zd 334 34 34 34 CD cord-015569-vy49r1zd 334 35 - - SYM cord-015569-vy49r1zd 334 36 37 37 CD cord-015569-vy49r1zd 334 37 weeks week NNS cord-015569-vy49r1zd 334 38 ) ) -RRB- cord-015569-vy49r1zd 334 39 Sprague Sprague NNP cord-015569-vy49r1zd 334 40 - - HYPH cord-015569-vy49r1zd 334 41 Dawley Dawley NNP cord-015569-vy49r1zd 334 42 male male JJ cord-015569-vy49r1zd 334 43 rats rat NNS cord-015569-vy49r1zd 334 44 . . . cord-015569-vy49r1zd 335 1 All all DT cord-015569-vy49r1zd 335 2 rats rat NNS cord-015569-vy49r1zd 335 3 were be VBD cord-015569-vy49r1zd 335 4 fed feed VBN cord-015569-vy49r1zd 335 5 ad ad NN cord-015569-vy49r1zd 335 6 libitum libitum NN cord-015569-vy49r1zd 335 7 during during IN cord-015569-vy49r1zd 335 8 all all DT cord-015569-vy49r1zd 335 9 tests test NNS cord-015569-vy49r1zd 335 10 . . . cord-015569-vy49r1zd 336 1 We -PRON- PRP cord-015569-vy49r1zd 336 2 used use VBD cord-015569-vy49r1zd 336 3 0.1 0.1 CD cord-015569-vy49r1zd 336 4 M m NN cord-015569-vy49r1zd 336 5 or or CC cord-015569-vy49r1zd 336 6 0.3 0.3 CD cord-015569-vy49r1zd 336 7 M M NNP cord-015569-vy49r1zd 336 8 NaCl nacl NN cord-015569-vy49r1zd 336 9 , , , cord-015569-vy49r1zd 336 10 0.01 0.01 CD cord-015569-vy49r1zd 336 11 M m NN cord-015569-vy49r1zd 336 12 or or CC cord-015569-vy49r1zd 336 13 0.1 0.1 CD cord-015569-vy49r1zd 336 14 M m CD cord-015569-vy49r1zd 336 15 HCl hcl NN cord-015569-vy49r1zd 336 16 , , , cord-015569-vy49r1zd 336 17 0.3 0.3 CD cord-015569-vy49r1zd 336 18 M m NN cord-015569-vy49r1zd 336 19 or or CC cord-015569-vy49r1zd 336 20 0.5 0.5 CD cord-015569-vy49r1zd 336 21 M M NNP cord-015569-vy49r1zd 336 22 sucrose sucrose NN cord-015569-vy49r1zd 336 23 , , , cord-015569-vy49r1zd 336 24 5 5 CD cord-015569-vy49r1zd 336 25 mM mm CD cord-015569-vy49r1zd 336 26 saccharin saccharin NN cord-015569-vy49r1zd 336 27 - - HYPH cord-015569-vy49r1zd 336 28 Na Na NNP cord-015569-vy49r1zd 336 29 , , , cord-015569-vy49r1zd 336 30 3·10 3·10 CD cord-015569-vy49r1zd 336 31 -4 -4 NNP cord-015569-vy49r1zd 336 32 M M NNP cord-015569-vy49r1zd 336 33 or or CC cord-015569-vy49r1zd 336 34 3·10 3·10 CD cord-015569-vy49r1zd 336 35 -5 -5 NNP cord-015569-vy49r1zd 337 1 M M NNP cord-015569-vy49r1zd 337 2 quinine quinine NN cord-015569-vy49r1zd 337 3 - - HYPH cord-015569-vy49r1zd 337 4 HCl hcl NN cord-015569-vy49r1zd 337 5 , , , cord-015569-vy49r1zd 337 6 and and CC cord-015569-vy49r1zd 337 7 0.1 0.1 CD cord-015569-vy49r1zd 337 8 M m NN cord-015569-vy49r1zd 337 9 monosodium monosodium NN cord-015569-vy49r1zd 337 10 glutamate glutamate NN cord-015569-vy49r1zd 337 11 ( ( -LRB- cord-015569-vy49r1zd 337 12 MSG MSG NNP cord-015569-vy49r1zd 337 13 ) ) -RRB- cord-015569-vy49r1zd 337 14 . . . cord-015569-vy49r1zd 338 1 The the DT cord-015569-vy49r1zd 338 2 preference preference NN cord-015569-vy49r1zd 338 3 ratio ratio NN cord-015569-vy49r1zd 338 4 for for IN cord-015569-vy49r1zd 338 5 0.5 0.5 CD cord-015569-vy49r1zd 338 6 M M NNP cord-015569-vy49r1zd 338 7 sucrose sucrose NN cord-015569-vy49r1zd 338 8 and and CC cord-015569-vy49r1zd 338 9 0.1 0.1 CD cord-015569-vy49r1zd 338 10 M m NN cord-015569-vy49r1zd 338 11 MSG msg NN cord-015569-vy49r1zd 338 12 in in IN cord-015569-vy49r1zd 338 13 middle middle NN cord-015569-vy49r1zd 338 14 - - HYPH cord-015569-vy49r1zd 338 15 aged aged JJ cord-015569-vy49r1zd 338 16 group group NN cord-015569-vy49r1zd 338 17 was be VBD cord-015569-vy49r1zd 338 18 lower low JJR cord-015569-vy49r1zd 338 19 than than IN cord-015569-vy49r1zd 338 20 that that DT cord-015569-vy49r1zd 338 21 in in IN cord-015569-vy49r1zd 338 22 juvenile juvenile JJ cord-015569-vy49r1zd 338 23 and and CC cord-015569-vy49r1zd 338 24 young young JJ cord-015569-vy49r1zd 338 25 - - HYPH cord-015569-vy49r1zd 338 26 adult adult NN cord-015569-vy49r1zd 338 27 groups group NNS cord-015569-vy49r1zd 338 28 . . . cord-015569-vy49r1zd 339 1 On on IN cord-015569-vy49r1zd 339 2 the the DT cord-015569-vy49r1zd 339 3 other other JJ cord-015569-vy49r1zd 339 4 hand hand NN cord-015569-vy49r1zd 339 5 , , , cord-015569-vy49r1zd 339 6 the the DT cord-015569-vy49r1zd 339 7 preference preference NN cord-015569-vy49r1zd 339 8 ratio ratio NN cord-015569-vy49r1zd 339 9 for for IN cord-015569-vy49r1zd 339 10 3·10 3·10 CD cord-015569-vy49r1zd 339 11 -5 -5 NNP cord-015569-vy49r1zd 339 12 M m CD cord-015569-vy49r1zd 339 13 quinine quinine NN cord-015569-vy49r1zd 339 14 - - HYPH cord-015569-vy49r1zd 339 15 HCl hcl NN cord-015569-vy49r1zd 339 16 in in IN cord-015569-vy49r1zd 339 17 middle middle NN cord-015569-vy49r1zd 339 18 - - HYPH cord-015569-vy49r1zd 339 19 aged aged JJ cord-015569-vy49r1zd 339 20 group group NN cord-015569-vy49r1zd 339 21 was be VBD cord-015569-vy49r1zd 339 22 higher high JJR cord-015569-vy49r1zd 339 23 than than IN cord-015569-vy49r1zd 339 24 that that DT cord-015569-vy49r1zd 339 25 in in IN cord-015569-vy49r1zd 339 26 juvenile juvenile JJ cord-015569-vy49r1zd 339 27 and and CC cord-015569-vy49r1zd 339 28 young young JJ cord-015569-vy49r1zd 339 29 - - HYPH cord-015569-vy49r1zd 339 30 adult adult NN cord-015569-vy49r1zd 339 31 groups group NNS cord-015569-vy49r1zd 339 32 . . . cord-015569-vy49r1zd 340 1 There there EX cord-015569-vy49r1zd 340 2 were be VBD cord-015569-vy49r1zd 340 3 no no DT cord-015569-vy49r1zd 340 4 significant significant JJ cord-015569-vy49r1zd 340 5 differences difference NNS cord-015569-vy49r1zd 340 6 in in IN cord-015569-vy49r1zd 340 7 the the DT cord-015569-vy49r1zd 340 8 preference preference NN cord-015569-vy49r1zd 340 9 for for IN cord-015569-vy49r1zd 340 10 HCl hcl NN cord-015569-vy49r1zd 340 11 and and CC cord-015569-vy49r1zd 340 12 NaCl nacl NN cord-015569-vy49r1zd 340 13 tastes taste NNS cord-015569-vy49r1zd 340 14 among among IN cord-015569-vy49r1zd 340 15 groups group NNS cord-015569-vy49r1zd 340 16 . . . cord-015569-vy49r1zd 341 1 These these DT cord-015569-vy49r1zd 341 2 results result NNS cord-015569-vy49r1zd 341 3 suggest suggest VBP cord-015569-vy49r1zd 341 4 that that IN cord-015569-vy49r1zd 341 5 aging aging NN cord-015569-vy49r1zd 341 6 affects affect VBZ cord-015569-vy49r1zd 341 7 taste taste NN cord-015569-vy49r1zd 341 8 preferences preference NNS cord-015569-vy49r1zd 341 9 for for IN cord-015569-vy49r1zd 341 10 sucrose sucrose NN cord-015569-vy49r1zd 341 11 , , , cord-015569-vy49r1zd 341 12 MSG msg NN cord-015569-vy49r1zd 341 13 and and CC cord-015569-vy49r1zd 341 14 quinine quinine NN cord-015569-vy49r1zd 341 15 - - HYPH cord-015569-vy49r1zd 341 16 HCl hcl NN cord-015569-vy49r1zd 341 17 which which WDT cord-015569-vy49r1zd 341 18 represent represent VBP cord-015569-vy49r1zd 341 19 sweet sweet JJ cord-015569-vy49r1zd 341 20 , , , cord-015569-vy49r1zd 341 21 umami umami NN cord-015569-vy49r1zd 341 22 and and CC cord-015569-vy49r1zd 341 23 bitter bitter JJ cord-015569-vy49r1zd 341 24 tastes taste NNS cord-015569-vy49r1zd 341 25 , , , cord-015569-vy49r1zd 341 26 respectively respectively RB cord-015569-vy49r1zd 341 27 , , , cord-015569-vy49r1zd 341 28 in in IN cord-015569-vy49r1zd 341 29 humans human NNS cord-015569-vy49r1zd 341 30 . . . cord-015569-vy49r1zd 342 1 We -PRON- PRP cord-015569-vy49r1zd 342 2 investigated investigate VBD cord-015569-vy49r1zd 342 3 the the DT cord-015569-vy49r1zd 342 4 effects effect NNS cord-015569-vy49r1zd 342 5 of of IN cord-015569-vy49r1zd 342 6 furanones furanone NNS cord-015569-vy49r1zd 342 7 as as IN cord-015569-vy49r1zd 342 8 the the DT cord-015569-vy49r1zd 342 9 Maillard Maillard NNP cord-015569-vy49r1zd 342 10 reaction reaction NN cord-015569-vy49r1zd 342 11 products product NNS cord-015569-vy49r1zd 342 12 flavors flavor NNS cord-015569-vy49r1zd 342 13 on on IN cord-015569-vy49r1zd 342 14 umami umami NN cord-015569-vy49r1zd 342 15 and and CC cord-015569-vy49r1zd 342 16 sweet sweet JJ cord-015569-vy49r1zd 342 17 taste taste NN cord-015569-vy49r1zd 342 18 preferences preference NNS cord-015569-vy49r1zd 342 19 in in IN cord-015569-vy49r1zd 342 20 mice mouse NNS cord-015569-vy49r1zd 342 21 . . . cord-015569-vy49r1zd 343 1 5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one 5-dimethyl-3-hydroxy-2,5-dihydrofuran-2-one CD cord-015569-vy49r1zd 343 2 ; ; : cord-015569-vy49r1zd 343 3 sotolon sotolon NNP cord-015569-vy49r1zd 343 4 and and CC cord-015569-vy49r1zd 343 5 4-hydroxy-2,5-dimethyl-3(2H)-furanone 4-hydroxy-2,5-dimethyl-3(2h)-furanone CD cord-015569-vy49r1zd 343 6 ; ; : cord-015569-vy49r1zd 343 7 furaneol furaneol NNP cord-015569-vy49r1zd 343 8 ( ( -LRB- cord-015569-vy49r1zd 343 9 Food food NN cord-015569-vy49r1zd 343 10 - - HYPH cord-015569-vy49r1zd 343 11 Grade Grade NNP cord-015569-vy49r1zd 343 12 Certified Certified NNP cord-015569-vy49r1zd 343 13 Products Products NNP cord-015569-vy49r1zd 343 14 , , , cord-015569-vy49r1zd 343 15 SAFC SAFC NNP cord-015569-vy49r1zd 343 16 Supply Supply NNP cord-015569-vy49r1zd 343 17 Solutions Solutions NNPS cord-015569-vy49r1zd 343 18 , , , cord-015569-vy49r1zd 343 19 USA USA NNP cord-015569-vy49r1zd 343 20 ) ) -RRB- cord-015569-vy49r1zd 343 21 were be VBD cord-015569-vy49r1zd 343 22 chosen choose VBN cord-015569-vy49r1zd 343 23 as as IN cord-015569-vy49r1zd 343 24 the the DT cord-015569-vy49r1zd 343 25 Maillard Maillard NNP cord-015569-vy49r1zd 343 26 - - HYPH cord-015569-vy49r1zd 343 27 borne bear VBN cord-015569-vy49r1zd 343 28 odorants odorant NNS cord-015569-vy49r1zd 343 29 . . . cord-015569-vy49r1zd 344 1 In in IN cord-015569-vy49r1zd 344 2 the the DT cord-015569-vy49r1zd 344 3 short short JJ cord-015569-vy49r1zd 344 4 time time NN cord-015569-vy49r1zd 344 5 two two CD cord-015569-vy49r1zd 344 6 - - HYPH cord-015569-vy49r1zd 344 7 bottle bottle NN cord-015569-vy49r1zd 344 8 tests test NNS cord-015569-vy49r1zd 344 9 , , , cord-015569-vy49r1zd 344 10 0.001 0.001 CD cord-015569-vy49r1zd 344 11 , , , cord-015569-vy49r1zd 344 12 0.003 0.003 CD cord-015569-vy49r1zd 344 13 , , , cord-015569-vy49r1zd 344 14 0.03 0.03 CD cord-015569-vy49r1zd 344 15 , , , cord-015569-vy49r1zd 344 16 0.1 0.1 CD cord-015569-vy49r1zd 344 17 lg lg NNP cord-015569-vy49r1zd 344 18 / / SYM cord-015569-vy49r1zd 344 19 kg kg NNP cord-015569-vy49r1zd 344 20 sotolon sotolon NNP cord-015569-vy49r1zd 344 21 flavored flavored JJ cord-015569-vy49r1zd 344 22 umami umami NN cord-015569-vy49r1zd 344 23 solutions solution NNS cord-015569-vy49r1zd 344 24 containing contain VBG cord-015569-vy49r1zd 344 25 10 10 CD cord-015569-vy49r1zd 344 26 mM mm CD cord-015569-vy49r1zd 344 27 monosodium monosodium NN cord-015569-vy49r1zd 344 28 glutamate glutamate NN cord-015569-vy49r1zd 344 29 ( ( -LRB- cord-015569-vy49r1zd 344 30 MSG MSG NNP cord-015569-vy49r1zd 344 31 ) ) -RRB- cord-015569-vy49r1zd 344 32 and and CC cord-015569-vy49r1zd 344 33 sweet sweet JJ cord-015569-vy49r1zd 344 34 solutions solution NNS cord-015569-vy49r1zd 344 35 containing contain VBG cord-015569-vy49r1zd 344 36 1 1 CD cord-015569-vy49r1zd 344 37 mM mm CD cord-015569-vy49r1zd 344 38 saccharin saccharin NN cord-015569-vy49r1zd 344 39 were be VBD cord-015569-vy49r1zd 344 40 significantly significantly RB cord-015569-vy49r1zd 344 41 consumed consume VBN cord-015569-vy49r1zd 344 42 more more JJR cord-015569-vy49r1zd 344 43 than than IN cord-015569-vy49r1zd 344 44 distilled distilled JJ cord-015569-vy49r1zd 344 45 water water NN cord-015569-vy49r1zd 344 46 . . . cord-015569-vy49r1zd 345 1 Sotolon Sotolon NNP cord-015569-vy49r1zd 345 2 tended tend VBD cord-015569-vy49r1zd 345 3 to to TO cord-015569-vy49r1zd 345 4 enhance enhance VB cord-015569-vy49r1zd 345 5 umami umami NN cord-015569-vy49r1zd 345 6 and and CC cord-015569-vy49r1zd 345 7 sweet sweet JJ cord-015569-vy49r1zd 345 8 taste taste NN cord-015569-vy49r1zd 345 9 preference preference NN cord-015569-vy49r1zd 345 10 in in IN cord-015569-vy49r1zd 345 11 a a DT cord-015569-vy49r1zd 345 12 dose dose NN cord-015569-vy49r1zd 345 13 dependant dependant JJ cord-015569-vy49r1zd 345 14 manner manner NN cord-015569-vy49r1zd 345 15 . . . cord-015569-vy49r1zd 346 1 Whereas whereas IN cord-015569-vy49r1zd 346 2 there there EX cord-015569-vy49r1zd 346 3 were be VBD cord-015569-vy49r1zd 346 4 no no DT cord-015569-vy49r1zd 346 5 differences difference NNS cord-015569-vy49r1zd 346 6 of of IN cord-015569-vy49r1zd 346 7 intakes intake NNS cord-015569-vy49r1zd 346 8 between between IN cord-015569-vy49r1zd 346 9 sotolon sotolon NNP cord-015569-vy49r1zd 346 10 flavored flavored JJ cord-015569-vy49r1zd 346 11 water water NN cord-015569-vy49r1zd 346 12 and and CC cord-015569-vy49r1zd 346 13 distilled distilled JJ cord-015569-vy49r1zd 346 14 water water NN cord-015569-vy49r1zd 346 15 . . . cord-015569-vy49r1zd 347 1 In in IN cord-015569-vy49r1zd 347 2 addition addition NN cord-015569-vy49r1zd 347 3 , , , cord-015569-vy49r1zd 347 4 furaneol furaneol NNP cord-015569-vy49r1zd 347 5 and and CC cord-015569-vy49r1zd 347 6 citral citral NNP cord-015569-vy49r1zd 347 7 flavor flavor NN cord-015569-vy49r1zd 347 8 agents agent NNS cord-015569-vy49r1zd 347 9 did do VBD cord-015569-vy49r1zd 347 10 not not RB cord-015569-vy49r1zd 347 11 enhance enhance VB cord-015569-vy49r1zd 347 12 umami umami NN cord-015569-vy49r1zd 347 13 solution solution NN cord-015569-vy49r1zd 347 14 preferences preference NNS cord-015569-vy49r1zd 347 15 . . . cord-015569-vy49r1zd 348 1 These these DT cord-015569-vy49r1zd 348 2 results result NNS cord-015569-vy49r1zd 348 3 suggested suggest VBD cord-015569-vy49r1zd 348 4 that that IN cord-015569-vy49r1zd 348 5 sotolon sotolon NNP cord-015569-vy49r1zd 348 6 , , , cord-015569-vy49r1zd 348 7 one one CD cord-015569-vy49r1zd 348 8 of of IN cord-015569-vy49r1zd 348 9 the the DT cord-015569-vy49r1zd 348 10 Maillard Maillard NNP cord-015569-vy49r1zd 348 11 reaction reaction NN cord-015569-vy49r1zd 348 12 products product NNS cord-015569-vy49r1zd 348 13 , , , cord-015569-vy49r1zd 348 14 induced induce VBN cord-015569-vy49r1zd 348 15 enhancement enhancement NN cord-015569-vy49r1zd 348 16 of of IN cord-015569-vy49r1zd 348 17 umami umami NN cord-015569-vy49r1zd 348 18 and and CC cord-015569-vy49r1zd 348 19 sweet sweet JJ cord-015569-vy49r1zd 348 20 taste taste NN cord-015569-vy49r1zd 348 21 preference preference NN cord-015569-vy49r1zd 348 22 in in IN cord-015569-vy49r1zd 348 23 mice mouse NNS cord-015569-vy49r1zd 348 24 . . . cord-015569-vy49r1zd 349 1 Supported support VBN cord-015569-vy49r1zd 349 2 by by IN cord-015569-vy49r1zd 349 3 Society Society NNP cord-015569-vy49r1zd 349 4 for for IN cord-015569-vy49r1zd 349 5 Research Research NNP cord-015569-vy49r1zd 349 6 on on IN cord-015569-vy49r1zd 349 7 Umami Umami NNP cord-015569-vy49r1zd 349 8 Taste Taste NNP cord-015569-vy49r1zd 349 9 and and CC cord-015569-vy49r1zd 349 10 KAKENHI KAKENHI NNP cord-015569-vy49r1zd 349 11 ( ( -LRB- cord-015569-vy49r1zd 349 12 22780127 22780127 CD cord-015569-vy49r1zd 349 13 ) ) -RRB- cord-015569-vy49r1zd 349 14 . . . cord-015569-vy49r1zd 350 1 Zinc zinc NN cord-015569-vy49r1zd 350 2 is be VBZ cord-015569-vy49r1zd 350 3 one one CD cord-015569-vy49r1zd 350 4 of of IN cord-015569-vy49r1zd 350 5 the the DT cord-015569-vy49r1zd 350 6 essential essential JJ cord-015569-vy49r1zd 350 7 trace trace NN cord-015569-vy49r1zd 350 8 elements element NNS cord-015569-vy49r1zd 350 9 and and CC cord-015569-vy49r1zd 350 10 its -PRON- PRP$ cord-015569-vy49r1zd 350 11 deficiency deficiency NN cord-015569-vy49r1zd 350 12 causes cause VBZ cord-015569-vy49r1zd 350 13 anorexia anorexia NN cord-015569-vy49r1zd 350 14 , , , cord-015569-vy49r1zd 350 15 growth growth NN cord-015569-vy49r1zd 350 16 retardation retardation NN cord-015569-vy49r1zd 350 17 , , , cord-015569-vy49r1zd 350 18 and and CC cord-015569-vy49r1zd 350 19 taste taste VB cord-015569-vy49r1zd 350 20 disorder disorder NN cord-015569-vy49r1zd 350 21 . . . cord-015569-vy49r1zd 351 1 Insulin insulin NN cord-015569-vy49r1zd 351 2 in in IN cord-015569-vy49r1zd 351 3 pancreatic pancreatic JJ cord-015569-vy49r1zd 351 4 beta beta NN cord-015569-vy49r1zd 351 5 - - HYPH cord-015569-vy49r1zd 351 6 cells cell NNS cord-015569-vy49r1zd 351 7 is be VBZ cord-015569-vy49r1zd 351 8 known know VBN cord-015569-vy49r1zd 351 9 to to TO cord-015569-vy49r1zd 351 10 be be VB cord-015569-vy49r1zd 351 11 stored store VBN cord-015569-vy49r1zd 351 12 as as IN cord-015569-vy49r1zd 351 13 microcrystals microcrystal NNS cord-015569-vy49r1zd 351 14 of of IN cord-015569-vy49r1zd 351 15 the the DT cord-015569-vy49r1zd 351 16 zinc zinc NN cord-015569-vy49r1zd 351 17 - - HYPH cord-015569-vy49r1zd 351 18 containing contain VBG cord-015569-vy49r1zd 351 19 hexamer hexamer NN cord-015569-vy49r1zd 351 20 , , , cord-015569-vy49r1zd 351 21 and and CC cord-015569-vy49r1zd 351 22 zinc zinc NN cord-015569-vy49r1zd 351 23 is be VBZ cord-015569-vy49r1zd 351 24 thought think VBN cord-015569-vy49r1zd 351 25 to to TO cord-015569-vy49r1zd 351 26 be be VB cord-015569-vy49r1zd 351 27 fundamentally fundamentally RB cord-015569-vy49r1zd 351 28 important important JJ cord-015569-vy49r1zd 351 29 for for IN cord-015569-vy49r1zd 351 30 assembly assembly NN cord-015569-vy49r1zd 351 31 and and CC cord-015569-vy49r1zd 351 32 release release NN cord-015569-vy49r1zd 351 33 of of IN cord-015569-vy49r1zd 351 34 insulin insulin NN cord-015569-vy49r1zd 351 35 from from IN cord-015569-vy49r1zd 351 36 beta beta NN cord-015569-vy49r1zd 351 37 - - HYPH cord-015569-vy49r1zd 351 38 cells cell NNS cord-015569-vy49r1zd 351 39 . . . cord-015569-vy49r1zd 352 1 However however RB cord-015569-vy49r1zd 352 2 , , , cord-015569-vy49r1zd 352 3 the the DT cord-015569-vy49r1zd 352 4 effect effect NN cord-015569-vy49r1zd 352 5 of of IN cord-015569-vy49r1zd 352 6 dietary dietary JJ cord-015569-vy49r1zd 352 7 zinc zinc NN cord-015569-vy49r1zd 352 8 on on IN cord-015569-vy49r1zd 352 9 food food NN cord-015569-vy49r1zd 352 10 intake intake NN cord-015569-vy49r1zd 352 11 or or CC cord-015569-vy49r1zd 352 12 insulin insulin NN cord-015569-vy49r1zd 352 13 secretion secretion NN cord-015569-vy49r1zd 352 14 of of IN cord-015569-vy49r1zd 352 15 model model NN cord-015569-vy49r1zd 352 16 rats rat NNS cord-015569-vy49r1zd 352 17 of of IN cord-015569-vy49r1zd 352 18 diabetes diabetes NN cord-015569-vy49r1zd 352 19 has have VBZ cord-015569-vy49r1zd 352 20 not not RB cord-015569-vy49r1zd 352 21 been be VBN cord-015569-vy49r1zd 352 22 well well RB cord-015569-vy49r1zd 352 23 elucidated elucidate VBN cord-015569-vy49r1zd 352 24 . . . cord-015569-vy49r1zd 353 1 In in IN cord-015569-vy49r1zd 353 2 this this DT cord-015569-vy49r1zd 353 3 study study NN cord-015569-vy49r1zd 353 4 , , , cord-015569-vy49r1zd 353 5 we -PRON- PRP cord-015569-vy49r1zd 353 6 followed follow VBD cord-015569-vy49r1zd 353 7 the the DT cord-015569-vy49r1zd 353 8 levels level NNS cord-015569-vy49r1zd 353 9 of of IN cord-015569-vy49r1zd 353 10 food food NN cord-015569-vy49r1zd 353 11 intake intake NN cord-015569-vy49r1zd 353 12 and and CC cord-015569-vy49r1zd 353 13 insulin insulin NN cord-015569-vy49r1zd 353 14 secretion secretion NN cord-015569-vy49r1zd 353 15 in in IN cord-015569-vy49r1zd 353 16 Type type NN cord-015569-vy49r1zd 353 17 2 2 CD cord-015569-vy49r1zd 353 18 diabetes diabetes NN cord-015569-vy49r1zd 353 19 model model NN cord-015569-vy49r1zd 353 20 GK GK NNP cord-015569-vy49r1zd 353 21 ( ( -LRB- cord-015569-vy49r1zd 353 22 Goto Goto NNP cord-015569-vy49r1zd 353 23 - - HYPH cord-015569-vy49r1zd 353 24 Kakizaki Kakizaki NNP cord-015569-vy49r1zd 353 25 ) ) -RRB- cord-015569-vy49r1zd 353 26 rats rat NNS cord-015569-vy49r1zd 353 27 fed feed VBD cord-015569-vy49r1zd 353 28 on on IN cord-015569-vy49r1zd 353 29 diets diet NNS cord-015569-vy49r1zd 353 30 containing contain VBG cord-015569-vy49r1zd 353 31 different different JJ cord-015569-vy49r1zd 353 32 levels level NNS cord-015569-vy49r1zd 353 33 of of IN cord-015569-vy49r1zd 353 34 dietary dietary JJ cord-015569-vy49r1zd 353 35 zinc zinc NN cord-015569-vy49r1zd 353 36 for for IN cord-015569-vy49r1zd 353 37 27 27 CD cord-015569-vy49r1zd 353 38 weeks week NNS cord-015569-vy49r1zd 353 39 . . . cord-015569-vy49r1zd 354 1 All all PDT cord-015569-vy49r1zd 354 2 the the DT cord-015569-vy49r1zd 354 3 experimental experimental JJ cord-015569-vy49r1zd 354 4 rats rat NNS cord-015569-vy49r1zd 354 5 were be VBD cord-015569-vy49r1zd 354 6 divided divide VBN cord-015569-vy49r1zd 354 7 into into IN cord-015569-vy49r1zd 354 8 four four CD cord-015569-vy49r1zd 354 9 experimental experimental JJ cord-015569-vy49r1zd 354 10 groups group NNS cord-015569-vy49r1zd 354 11 of of IN cord-015569-vy49r1zd 354 12 zinc zinc NN cord-015569-vy49r1zd 354 13 - - HYPH cord-015569-vy49r1zd 354 14 deficient deficient JJ cord-015569-vy49r1zd 354 15 ( ( -LRB- cord-015569-vy49r1zd 354 16 Zn Zn NNP cord-015569-vy49r1zd 354 17 - - HYPH cord-015569-vy49r1zd 354 18 Def Def NNP cord-015569-vy49r1zd 354 19 , , , cord-015569-vy49r1zd 354 20 rats rat NNS cord-015569-vy49r1zd 354 21 fed feed VBD cord-015569-vy49r1zd 354 22 on on IN cord-015569-vy49r1zd 354 23 2.2 2.2 CD cord-015569-vy49r1zd 354 24 mg mg NNP cord-015569-vy49r1zd 354 25 / / SYM cord-015569-vy49r1zd 354 26 kg kg NNP cord-015569-vy49r1zd 354 27 diet diet NN cord-015569-vy49r1zd 354 28 ) ) -RRB- cord-015569-vy49r1zd 354 29 , , , cord-015569-vy49r1zd 354 30 zinc zinc NN cord-015569-vy49r1zd 354 31 - - HYPH cord-015569-vy49r1zd 354 32 sufficient sufficient JJ cord-015569-vy49r1zd 355 1 ( ( -LRB- cord-015569-vy49r1zd 355 2 Zn Zn NNP cord-015569-vy49r1zd 355 3 - - HYPH cord-015569-vy49r1zd 355 4 Suf Suf NNP cord-015569-vy49r1zd 355 5 , , , cord-015569-vy49r1zd 355 6 rats rat NNS cord-015569-vy49r1zd 355 7 fed feed VBD cord-015569-vy49r1zd 355 8 on on IN cord-015569-vy49r1zd 355 9 33.7 33.7 CD cord-015569-vy49r1zd 355 10 mg mg NNP cord-015569-vy49r1zd 355 11 / / SYM cord-015569-vy49r1zd 355 12 kg kg NNP cord-015569-vy49r1zd 355 13 diet diet NN cord-015569-vy49r1zd 355 14 ) ) -RRB- cord-015569-vy49r1zd 355 15 , , , cord-015569-vy49r1zd 355 16 high high JJ cord-015569-vy49r1zd 355 17 - - HYPH cord-015569-vy49r1zd 355 18 zinc zinc NN cord-015569-vy49r1zd 355 19 ( ( -LRB- cord-015569-vy49r1zd 355 20 High High NNP cord-015569-vy49r1zd 355 21 - - HYPH cord-015569-vy49r1zd 355 22 Zn Zn NNP cord-015569-vy49r1zd 355 23 , , , cord-015569-vy49r1zd 355 24 rats rat NNS cord-015569-vy49r1zd 355 25 fed feed VBD cord-015569-vy49r1zd 355 26 on on IN cord-015569-vy49r1zd 355 27 67.4 67.4 CD cord-015569-vy49r1zd 355 28 mg mg NNP cord-015569-vy49r1zd 355 29 / / SYM cord-015569-vy49r1zd 355 30 kg kg NNP cord-015569-vy49r1zd 355 31 diet diet NNP cord-015569-vy49r1zd 355 32 ) ) -RRB- cord-015569-vy49r1zd 355 33 , , , cord-015569-vy49r1zd 355 34 and and CC cord-015569-vy49r1zd 355 35 Pair Pair NNP cord-015569-vy49r1zd 355 36 - - HYPH cord-015569-vy49r1zd 355 37 Fed Fed NNP cord-015569-vy49r1zd 355 38 ( ( -LRB- cord-015569-vy49r1zd 355 39 rats rat NNS cord-015569-vy49r1zd 355 40 fed feed VBD cord-015569-vy49r1zd 355 41 on on IN cord-015569-vy49r1zd 355 42 zinc zinc NN cord-015569-vy49r1zd 355 43 - - HYPH cord-015569-vy49r1zd 355 44 sufficient sufficient JJ cord-015569-vy49r1zd 355 45 diet diet NN cord-015569-vy49r1zd 355 46 with with IN cord-015569-vy49r1zd 355 47 the the DT cord-015569-vy49r1zd 355 48 same same JJ cord-015569-vy49r1zd 355 49 amount amount NN cord-015569-vy49r1zd 355 50 of of IN cord-015569-vy49r1zd 355 51 diet diet NN cord-015569-vy49r1zd 355 52 consumed consume VBN cord-015569-vy49r1zd 355 53 by by IN cord-015569-vy49r1zd 355 54 Zn Zn NNP cord-015569-vy49r1zd 355 55 - - HYPH cord-015569-vy49r1zd 355 56 Def Def NNP cord-015569-vy49r1zd 355 57 one one CD cord-015569-vy49r1zd 355 58 day day NN cord-015569-vy49r1zd 355 59 later later RBR cord-015569-vy49r1zd 355 60 ) ) -RRB- cord-015569-vy49r1zd 355 61 . . . cord-015569-vy49r1zd 356 1 Food food NN cord-015569-vy49r1zd 356 2 intake intake NN cord-015569-vy49r1zd 356 3 in in IN cord-015569-vy49r1zd 356 4 Zn Zn NNP cord-015569-vy49r1zd 356 5 - - HYPH cord-015569-vy49r1zd 356 6 Def Def NNP cord-015569-vy49r1zd 356 7 GK GK NNP cord-015569-vy49r1zd 356 8 rats rat NNS cord-015569-vy49r1zd 356 9 followed follow VBD cord-015569-vy49r1zd 356 10 typical typical JJ cord-015569-vy49r1zd 356 11 cyclic cyclic JJ cord-015569-vy49r1zd 356 12 - - HYPH cord-015569-vy49r1zd 356 13 pattern pattern NN cord-015569-vy49r1zd 356 14 seen see VBN cord-015569-vy49r1zd 356 15 with with IN cord-015569-vy49r1zd 356 16 normal normal JJ cord-015569-vy49r1zd 356 17 rats rat NNS cord-015569-vy49r1zd 356 18 such such JJ cord-015569-vy49r1zd 356 19 as as IN cord-015569-vy49r1zd 356 20 SD SD NNP cord-015569-vy49r1zd 356 21 rats rat NNS cord-015569-vy49r1zd 356 22 . . . cord-015569-vy49r1zd 357 1 Plasma plasma NN cord-015569-vy49r1zd 357 2 zinc zinc NN cord-015569-vy49r1zd 357 3 concentrations concentration NNS cord-015569-vy49r1zd 357 4 and and CC cord-015569-vy49r1zd 357 5 plasma plasma NN cord-015569-vy49r1zd 357 6 insulin insulin NN cord-015569-vy49r1zd 357 7 concentrations concentration NNS cord-015569-vy49r1zd 357 8 were be VBD cord-015569-vy49r1zd 357 9 found find VBN cord-015569-vy49r1zd 357 10 to to TO cord-015569-vy49r1zd 357 11 have have VB cord-015569-vy49r1zd 357 12 positive positive JJ cord-015569-vy49r1zd 357 13 correlations correlation NNS cord-015569-vy49r1zd 357 14 in in IN cord-015569-vy49r1zd 357 15 High High NNP cord-015569-vy49r1zd 357 16 - - HYPH cord-015569-vy49r1zd 357 17 Zn Zn NNP cord-015569-vy49r1zd 357 18 rats rat NNS cord-015569-vy49r1zd 357 19 . . . cord-015569-vy49r1zd 358 1 Orexins orexin NNS cord-015569-vy49r1zd 358 2 are be VBP cord-015569-vy49r1zd 358 3 neuropeptides neuropeptide NNS cord-015569-vy49r1zd 358 4 synthesized synthesize VBN cord-015569-vy49r1zd 358 5 mainly mainly RB cord-015569-vy49r1zd 358 6 in in IN cord-015569-vy49r1zd 358 7 the the DT cord-015569-vy49r1zd 358 8 lateral lateral JJ cord-015569-vy49r1zd 358 9 hypothalamic hypothalamic JJ cord-015569-vy49r1zd 358 10 area area NN cord-015569-vy49r1zd 358 11 and and CC cord-015569-vy49r1zd 358 12 are be VBP cord-015569-vy49r1zd 358 13 implicated implicate VBN cord-015569-vy49r1zd 358 14 in in IN cord-015569-vy49r1zd 358 15 the the DT cord-015569-vy49r1zd 358 16 regulation regulation NN cord-015569-vy49r1zd 358 17 of of IN cord-015569-vy49r1zd 358 18 food food NN cord-015569-vy49r1zd 358 19 intake intake NN cord-015569-vy49r1zd 358 20 in in IN cord-015569-vy49r1zd 358 21 addition addition NN cord-015569-vy49r1zd 358 22 to to IN cord-015569-vy49r1zd 358 23 arousal arousal NN cord-015569-vy49r1zd 358 24 . . . cord-015569-vy49r1zd 359 1 Since since IN cord-015569-vy49r1zd 359 2 swallowing swallowing NN cord-015569-vy49r1zd 359 3 is be VBZ cord-015569-vy49r1zd 359 4 early early JJ cord-015569-vy49r1zd 359 5 step step NN cord-015569-vy49r1zd 359 6 of of IN cord-015569-vy49r1zd 359 7 feeding feed VBG cord-015569-vy49r1zd 359 8 behavior behavior NN cord-015569-vy49r1zd 359 9 , , , cord-015569-vy49r1zd 359 10 orexins orexins NNP cord-015569-vy49r1zd 359 11 might may MD cord-015569-vy49r1zd 359 12 modify modify VB cord-015569-vy49r1zd 359 13 swallowing swallowing NN cord-015569-vy49r1zd 359 14 . . . cord-015569-vy49r1zd 360 1 In in IN cord-015569-vy49r1zd 360 2 the the DT cord-015569-vy49r1zd 360 3 present present JJ cord-015569-vy49r1zd 360 4 study study NN cord-015569-vy49r1zd 360 5 , , , cord-015569-vy49r1zd 360 6 we -PRON- PRP cord-015569-vy49r1zd 360 7 examined examine VBD cord-015569-vy49r1zd 360 8 the the DT cord-015569-vy49r1zd 360 9 effects effect NNS cord-015569-vy49r1zd 360 10 of of IN cord-015569-vy49r1zd 360 11 orexins orexin NNS cord-015569-vy49r1zd 360 12 on on IN cord-015569-vy49r1zd 360 13 the the DT cord-015569-vy49r1zd 360 14 reflex reflex NN cord-015569-vy49r1zd 360 15 swallowing swallowing NN cord-015569-vy49r1zd 360 16 using use VBG cord-015569-vy49r1zd 360 17 anaesthetized anaesthetize VBN cord-015569-vy49r1zd 360 18 rats rat NNS cord-015569-vy49r1zd 360 19 . . . cord-015569-vy49r1zd 361 1 Orexin orexin NN cord-015569-vy49r1zd 361 2 , , , cord-015569-vy49r1zd 361 3 which which WDT cord-015569-vy49r1zd 361 4 was be VBD cord-015569-vy49r1zd 361 5 dissolved dissolve VBN cord-015569-vy49r1zd 361 6 in in IN cord-015569-vy49r1zd 361 7 RingerÕs RingerÕs NNP cord-015569-vy49r1zd 361 8 solution solution NN cord-015569-vy49r1zd 361 9 , , , cord-015569-vy49r1zd 361 10 was be VBD cord-015569-vy49r1zd 361 11 administered administer VBN cord-015569-vy49r1zd 361 12 into into IN cord-015569-vy49r1zd 361 13 the the DT cord-015569-vy49r1zd 361 14 fourth fourth JJ cord-015569-vy49r1zd 361 15 ventricle ventricle NN cord-015569-vy49r1zd 361 16 . . . cord-015569-vy49r1zd 362 1 Orexin-1 Orexin-1 NNP cord-015569-vy49r1zd 362 2 receptor receptor NN cord-015569-vy49r1zd 362 3 antagonist antagonist NN cord-015569-vy49r1zd 362 4 ( ( -LRB- cord-015569-vy49r1zd 362 5 SB334867 SB334867 NNP cord-015569-vy49r1zd 362 6 ) ) -RRB- cord-015569-vy49r1zd 362 7 , , , cord-015569-vy49r1zd 362 8 which which WDT cord-015569-vy49r1zd 362 9 was be VBD cord-015569-vy49r1zd 362 10 dissolved dissolve VBN cord-015569-vy49r1zd 362 11 in in IN cord-015569-vy49r1zd 362 12 dimethyl dimethyl NN cord-015569-vy49r1zd 362 13 sulfoxide sulfoxide NN cord-015569-vy49r1zd 362 14 , , , cord-015569-vy49r1zd 362 15 was be VBD cord-015569-vy49r1zd 362 16 administered administer VBN cord-015569-vy49r1zd 362 17 into into IN cord-015569-vy49r1zd 362 18 the the DT cord-015569-vy49r1zd 362 19 fourth fourth JJ cord-015569-vy49r1zd 362 20 ventricle ventricle NN cord-015569-vy49r1zd 362 21 . . . cord-015569-vy49r1zd 363 1 Three three CD cord-015569-vy49r1zd 363 2 lL lL NNS cord-015569-vy49r1zd 363 3 of of IN cord-015569-vy49r1zd 363 4 drugs drug NNS cord-015569-vy49r1zd 363 5 were be VBD cord-015569-vy49r1zd 363 6 administered administer VBN cord-015569-vy49r1zd 363 7 using use VBG cord-015569-vy49r1zd 363 8 a a DT cord-015569-vy49r1zd 363 9 microsyringe microsyringe NN cord-015569-vy49r1zd 363 10 . . . cord-015569-vy49r1zd 364 1 Swallowing swallow VBG cord-015569-vy49r1zd 364 2 was be VBD cord-015569-vy49r1zd 364 3 induced induce VBN cord-015569-vy49r1zd 364 4 by by IN cord-015569-vy49r1zd 364 5 the the DT cord-015569-vy49r1zd 364 6 electrical electrical JJ cord-015569-vy49r1zd 364 7 stimulation stimulation NN cord-015569-vy49r1zd 364 8 ( ( -LRB- cord-015569-vy49r1zd 364 9 20 20 CD cord-015569-vy49r1zd 364 10 Hz Hz NNP cord-015569-vy49r1zd 364 11 , , , cord-015569-vy49r1zd 364 12 20 20 CD cord-015569-vy49r1zd 364 13 sec sec NNP cord-015569-vy49r1zd 364 14 ) ) -RRB- cord-015569-vy49r1zd 364 15 of of IN cord-015569-vy49r1zd 364 16 the the DT cord-015569-vy49r1zd 364 17 central central JJ cord-015569-vy49r1zd 364 18 cut cut NN cord-015569-vy49r1zd 364 19 end end NN cord-015569-vy49r1zd 364 20 of of IN cord-015569-vy49r1zd 364 21 the the DT cord-015569-vy49r1zd 364 22 superior superior JJ cord-015569-vy49r1zd 364 23 laryngeal laryngeal NN cord-015569-vy49r1zd 364 24 nerve nerve NN cord-015569-vy49r1zd 364 25 ( ( -LRB- cord-015569-vy49r1zd 364 26 SLN SLN NNP cord-015569-vy49r1zd 364 27 ) ) -RRB- cord-015569-vy49r1zd 364 28 and and CC cord-015569-vy49r1zd 364 29 was be VBD cord-015569-vy49r1zd 364 30 monitored monitor VBN cord-015569-vy49r1zd 364 31 by by IN cord-015569-vy49r1zd 364 32 recording record VBG cord-015569-vy49r1zd 364 33 the the DT cord-015569-vy49r1zd 364 34 electromyogram electromyogram NNP cord-015569-vy49r1zd 364 35 of of IN cord-015569-vy49r1zd 364 36 the the DT cord-015569-vy49r1zd 364 37 mylohyoideus mylohyoideus NNP cord-015569-vy49r1zd 364 38 muscle muscle NN cord-015569-vy49r1zd 364 39 . . . cord-015569-vy49r1zd 365 1 The the DT cord-015569-vy49r1zd 365 2 frequency frequency NN cord-015569-vy49r1zd 365 3 of of IN cord-015569-vy49r1zd 365 4 swallowing swallowing NN cord-015569-vy49r1zd 365 5 during during IN cord-015569-vy49r1zd 365 6 the the DT cord-015569-vy49r1zd 365 7 electrical electrical JJ cord-015569-vy49r1zd 365 8 stimulation stimulation NN cord-015569-vy49r1zd 365 9 of of IN cord-015569-vy49r1zd 365 10 the the DT cord-015569-vy49r1zd 365 11 SLN SLN NNP cord-015569-vy49r1zd 365 12 decreased decrease VBD cord-015569-vy49r1zd 365 13 after after IN cord-015569-vy49r1zd 365 14 the the DT cord-015569-vy49r1zd 365 15 administration administration NN cord-015569-vy49r1zd 365 16 of of IN cord-015569-vy49r1zd 365 17 orexin orexin NN cord-015569-vy49r1zd 365 18 - - : cord-015569-vy49r1zd 365 19 A a NN cord-015569-vy49r1zd 365 20 in in IN cord-015569-vy49r1zd 365 21 a a DT cord-015569-vy49r1zd 365 22 dose dose NN cord-015569-vy49r1zd 365 23 - - HYPH cord-015569-vy49r1zd 365 24 dependent dependent JJ cord-015569-vy49r1zd 365 25 manner manner NN cord-015569-vy49r1zd 365 26 . . . cord-015569-vy49r1zd 366 1 Significant significant JJ cord-015569-vy49r1zd 366 2 reduction reduction NN cord-015569-vy49r1zd 366 3 in in IN cord-015569-vy49r1zd 366 4 number number NN cord-015569-vy49r1zd 366 5 of of IN cord-015569-vy49r1zd 366 6 swallowing swallowing NN cord-015569-vy49r1zd 366 7 was be VBD cord-015569-vy49r1zd 366 8 observed observe VBN cord-015569-vy49r1zd 366 9 after after IN cord-015569-vy49r1zd 366 10 the the DT cord-015569-vy49r1zd 366 11 administration administration NN cord-015569-vy49r1zd 366 12 of of IN cord-015569-vy49r1zd 366 13 orexin orexin NN cord-015569-vy49r1zd 366 14 - - : cord-015569-vy49r1zd 366 15 A a NN cord-015569-vy49r1zd 366 16 at at IN cord-015569-vy49r1zd 366 17 the the DT cord-015569-vy49r1zd 366 18 dose dose NN cord-015569-vy49r1zd 366 19 of of IN cord-015569-vy49r1zd 366 20 1 1 CD cord-015569-vy49r1zd 366 21 or or CC cord-015569-vy49r1zd 366 22 3 3 CD cord-015569-vy49r1zd 366 23 nmol nmol NN cord-015569-vy49r1zd 366 24 . . . cord-015569-vy49r1zd 367 1 The the DT cord-015569-vy49r1zd 367 2 latency latency NN cord-015569-vy49r1zd 367 3 of of IN cord-015569-vy49r1zd 367 4 the the DT cord-015569-vy49r1zd 367 5 response response NN cord-015569-vy49r1zd 367 6 tended tend VBD cord-015569-vy49r1zd 367 7 to to TO cord-015569-vy49r1zd 367 8 be be VB cord-015569-vy49r1zd 367 9 longer long JJR cord-015569-vy49r1zd 367 10 in in IN cord-015569-vy49r1zd 367 11 the the DT cord-015569-vy49r1zd 367 12 presence presence NN cord-015569-vy49r1zd 367 13 of of IN cord-015569-vy49r1zd 367 14 orexin orexin NN cord-015569-vy49r1zd 367 15 - - HYPH cord-015569-vy49r1zd 367 16 A. a. NN cord-015569-vy49r1zd 368 1 The the DT cord-015569-vy49r1zd 368 2 administration administration NN cord-015569-vy49r1zd 368 3 of of IN cord-015569-vy49r1zd 368 4 orexin orexin NN cord-015569-vy49r1zd 368 5 - - HYPH cord-015569-vy49r1zd 368 6 B B NNP cord-015569-vy49r1zd 368 7 did do VBD cord-015569-vy49r1zd 368 8 not not RB cord-015569-vy49r1zd 368 9 affect affect VB cord-015569-vy49r1zd 368 10 the the DT cord-015569-vy49r1zd 368 11 frequency frequency NN cord-015569-vy49r1zd 368 12 of of IN cord-015569-vy49r1zd 368 13 swallowing swallowing NN cord-015569-vy49r1zd 368 14 . . . cord-015569-vy49r1zd 369 1 Pre pre JJ cord-015569-vy49r1zd 369 2 - - JJ cord-015569-vy49r1zd 369 3 administration administration NN cord-015569-vy49r1zd 369 4 of of IN cord-015569-vy49r1zd 369 5 SB334867 SB334867 NNP cord-015569-vy49r1zd 369 6 attenuated attenuate VBD cord-015569-vy49r1zd 369 7 the the DT cord-015569-vy49r1zd 369 8 magnitude magnitude NN cord-015569-vy49r1zd 369 9 of of IN cord-015569-vy49r1zd 369 10 inhibition inhibition NN cord-015569-vy49r1zd 369 11 of of IN cord-015569-vy49r1zd 369 12 swallowing swallow VBG cord-015569-vy49r1zd 369 13 frequency frequency NN cord-015569-vy49r1zd 369 14 induced induce VBN cord-015569-vy49r1zd 369 15 by by IN cord-015569-vy49r1zd 369 16 the the DT cord-015569-vy49r1zd 369 17 administration administration NN cord-015569-vy49r1zd 369 18 of of IN cord-015569-vy49r1zd 369 19 orexin orexin NN cord-015569-vy49r1zd 369 20 - - HYPH cord-015569-vy49r1zd 369 21 A. a. NN cord-015569-vy49r1zd 370 1 These these DT cord-015569-vy49r1zd 370 2 results result NNS cord-015569-vy49r1zd 370 3 suggest suggest VBP cord-015569-vy49r1zd 370 4 that that IN cord-015569-vy49r1zd 370 5 orexin orexin NN cord-015569-vy49r1zd 370 6 - - HYPH cord-015569-vy49r1zd 370 7 A a NN cord-015569-vy49r1zd 370 8 but but CC cord-015569-vy49r1zd 370 9 not not RB cord-015569-vy49r1zd 370 10 orexin orexin NN cord-015569-vy49r1zd 370 11 - - HYPH cord-015569-vy49r1zd 370 12 B b NN cord-015569-vy49r1zd 370 13 inhibits inhibit VBZ cord-015569-vy49r1zd 370 14 reflex reflex NN cord-015569-vy49r1zd 370 15 swallowing swallowing NN cord-015569-vy49r1zd 370 16 via via IN cord-015569-vy49r1zd 370 17 type type NN cord-015569-vy49r1zd 370 18 1 1 CD cord-015569-vy49r1zd 370 19 receptors receptor NNS cord-015569-vy49r1zd 370 20 situated situate VBN cord-015569-vy49r1zd 370 21 in in IN cord-015569-vy49r1zd 370 22 the the DT cord-015569-vy49r1zd 370 23 dorsal dorsal JJ cord-015569-vy49r1zd 370 24 medulla medulla NN cord-015569-vy49r1zd 370 25 where where WRB cord-015569-vy49r1zd 370 26 swallowing swallowing NN cord-015569-vy49r1zd 370 27 center center NN cord-015569-vy49r1zd 370 28 is be VBZ cord-015569-vy49r1zd 370 29 housed house VBN cord-015569-vy49r1zd 370 30 . . . cord-015569-vy49r1zd 371 1 This this DT cord-015569-vy49r1zd 371 2 work work NN cord-015569-vy49r1zd 371 3 was be VBD cord-015569-vy49r1zd 371 4 supported support VBN cord-015569-vy49r1zd 371 5 by by IN cord-015569-vy49r1zd 371 6 a a DT cord-015569-vy49r1zd 371 7 Grant Grant NNP cord-015569-vy49r1zd 371 8 - - HYPH cord-015569-vy49r1zd 371 9 in in IN cord-015569-vy49r1zd 371 10 - - HYPH cord-015569-vy49r1zd 371 11 Aid aid NN cord-015569-vy49r1zd 371 12 for for IN cord-015569-vy49r1zd 371 13 Scientific Scientific NNP cord-015569-vy49r1zd 371 14 Research Research NNP cord-015569-vy49r1zd 371 15 from from IN cord-015569-vy49r1zd 371 16 the the DT cord-015569-vy49r1zd 371 17 Japan Japan NNP cord-015569-vy49r1zd 371 18 Society Society NNP cord-015569-vy49r1zd 371 19 for for IN cord-015569-vy49r1zd 371 20 the the DT cord-015569-vy49r1zd 371 21 Promotion Promotion NNP cord-015569-vy49r1zd 371 22 of of IN cord-015569-vy49r1zd 371 23 Science Science NNP cord-015569-vy49r1zd 372 1 ( ( -LRB- cord-015569-vy49r1zd 372 2 No no UH cord-015569-vy49r1zd 372 3 : : : cord-015569-vy49r1zd 372 4 22592064 22592064 CD cord-015569-vy49r1zd 372 5 to to IN cord-015569-vy49r1zd 372 6 MK MK NNP cord-015569-vy49r1zd 372 7 ) ) -RRB- cord-015569-vy49r1zd 372 8 . . . cord-015569-vy49r1zd 373 1 Stimulation stimulation NN cord-015569-vy49r1zd 373 2 of of IN cord-015569-vy49r1zd 373 3 water water NN cord-015569-vy49r1zd 373 4 receptors receptor NNS cord-015569-vy49r1zd 373 5 in in IN cord-015569-vy49r1zd 373 6 the the DT cord-015569-vy49r1zd 373 7 laryngopharynx laryngopharynx NN cord-015569-vy49r1zd 373 8 ( ( -LRB- cord-015569-vy49r1zd 373 9 LP LP NNP cord-015569-vy49r1zd 373 10 ) ) -RRB- cord-015569-vy49r1zd 373 11 with with IN cord-015569-vy49r1zd 373 12 water water NN cord-015569-vy49r1zd 373 13 shortened shorten VBD cord-015569-vy49r1zd 373 14 the the DT cord-015569-vy49r1zd 373 15 swallowing swallowing NN cord-015569-vy49r1zd 373 16 interval interval NN cord-015569-vy49r1zd 373 17 in in IN cord-015569-vy49r1zd 373 18 voluntary voluntary JJ cord-015569-vy49r1zd 373 19 swallowing swallowing NN cord-015569-vy49r1zd 373 20 in in IN cord-015569-vy49r1zd 373 21 humans human NNS cord-015569-vy49r1zd 373 22 . . . cord-015569-vy49r1zd 374 1 We -PRON- PRP cord-015569-vy49r1zd 374 2 previously previously RB cord-015569-vy49r1zd 374 3 found find VBD cord-015569-vy49r1zd 374 4 that that DT cord-015569-vy49r1zd 374 5 excitation excitation NN cord-015569-vy49r1zd 374 6 of of IN cord-015569-vy49r1zd 374 7 water water NN cord-015569-vy49r1zd 374 8 receptors receptor NNS cord-015569-vy49r1zd 374 9 was be VBD cord-015569-vy49r1zd 374 10 due due JJ cord-015569-vy49r1zd 374 11 to to IN cord-015569-vy49r1zd 374 12 absence absence NN cord-015569-vy49r1zd 374 13 or or CC cord-015569-vy49r1zd 374 14 reduced reduce VBN cord-015569-vy49r1zd 374 15 concentration concentration NN cord-015569-vy49r1zd 374 16 of of IN cord-015569-vy49r1zd 374 17 Clin clin JJ cord-015569-vy49r1zd 374 18 fluids fluid NNS cord-015569-vy49r1zd 374 19 applied apply VBN cord-015569-vy49r1zd 374 20 to to IN cord-015569-vy49r1zd 374 21 the the DT cord-015569-vy49r1zd 374 22 LP LP NNP cord-015569-vy49r1zd 374 23 . . . cord-015569-vy49r1zd 375 1 Unstimulated unstimulated JJ cord-015569-vy49r1zd 375 2 saliva saliva NN cord-015569-vy49r1zd 375 3 contains contain VBZ cord-015569-vy49r1zd 375 4 a a DT cord-015569-vy49r1zd 375 5 low low JJ cord-015569-vy49r1zd 375 6 concentration concentration NN cord-015569-vy49r1zd 375 7 of of IN cord-015569-vy49r1zd 375 8 Cl Cl NNP cord-015569-vy49r1zd 375 9 - - HYPH cord-015569-vy49r1zd 375 10 . . . cord-015569-vy49r1zd 376 1 Thus thus RB cord-015569-vy49r1zd 376 2 , , , cord-015569-vy49r1zd 376 3 unstimulated unstimulated JJ cord-015569-vy49r1zd 376 4 saliva saliva NN cord-015569-vy49r1zd 376 5 may may MD cord-015569-vy49r1zd 376 6 excite excite VB cord-015569-vy49r1zd 376 7 water water NN cord-015569-vy49r1zd 376 8 receptors receptor NNS cord-015569-vy49r1zd 376 9 in in IN cord-015569-vy49r1zd 376 10 humans human NNS cord-015569-vy49r1zd 376 11 . . . cord-015569-vy49r1zd 377 1 The the DT cord-015569-vy49r1zd 377 2 aim aim NN cord-015569-vy49r1zd 377 3 of of IN cord-015569-vy49r1zd 377 4 the the DT cord-015569-vy49r1zd 377 5 present present JJ cord-015569-vy49r1zd 377 6 study study NN cord-015569-vy49r1zd 377 7 was be VBD cord-015569-vy49r1zd 377 8 to to TO cord-015569-vy49r1zd 377 9 evaluate evaluate VB cord-015569-vy49r1zd 377 10 the the DT cord-015569-vy49r1zd 377 11 role role NN cord-015569-vy49r1zd 377 12 of of IN cord-015569-vy49r1zd 377 13 unstimulated unstimulated JJ cord-015569-vy49r1zd 377 14 saliva saliva NN cord-015569-vy49r1zd 377 15 in in IN cord-015569-vy49r1zd 377 16 initiation initiation NN cord-015569-vy49r1zd 377 17 of of IN cord-015569-vy49r1zd 377 18 swallowing swallow VBG cord-015569-vy49r1zd 377 19 in in IN cord-015569-vy49r1zd 377 20 humans human NNS cord-015569-vy49r1zd 377 21 . . . cord-015569-vy49r1zd 378 1 Solutions solution NNS cord-015569-vy49r1zd 378 2 were be VBD cord-015569-vy49r1zd 378 3 infused infuse VBN cord-015569-vy49r1zd 378 4 through through IN cord-015569-vy49r1zd 378 5 a a DT cord-015569-vy49r1zd 378 6 fine fine JJ cord-015569-vy49r1zd 378 7 tube tube NN cord-015569-vy49r1zd 378 8 into into IN cord-015569-vy49r1zd 378 9 the the DT cord-015569-vy49r1zd 378 10 LP LP NNP cord-015569-vy49r1zd 378 11 at at IN cord-015569-vy49r1zd 378 12 a a DT cord-015569-vy49r1zd 378 13 slow slow JJ cord-015569-vy49r1zd 378 14 infusion infusion NN cord-015569-vy49r1zd 378 15 rate rate NN cord-015569-vy49r1zd 378 16 ( ( -LRB- cord-015569-vy49r1zd 378 17 0.2 0.2 CD cord-015569-vy49r1zd 378 18 mL ml NN cord-015569-vy49r1zd 378 19 / / SYM cord-015569-vy49r1zd 378 20 min min NN cord-015569-vy49r1zd 378 21 ) ) -RRB- cord-015569-vy49r1zd 378 22 that that WDT cord-015569-vy49r1zd 378 23 minimized minimize VBD cord-015569-vy49r1zd 378 24 the the DT cord-015569-vy49r1zd 378 25 mechanical mechanical JJ cord-015569-vy49r1zd 378 26 effect effect NN cord-015569-vy49r1zd 378 27 of of IN cord-015569-vy49r1zd 378 28 infusion infusion NN cord-015569-vy49r1zd 378 29 . . . cord-015569-vy49r1zd 379 1 Facilitation facilitation NN cord-015569-vy49r1zd 379 2 of of IN cord-015569-vy49r1zd 379 3 voluntary voluntary JJ cord-015569-vy49r1zd 379 4 swallowing swallowing NN cord-015569-vy49r1zd 379 5 by by IN cord-015569-vy49r1zd 379 6 infusion infusion NN cord-015569-vy49r1zd 379 7 of of IN cord-015569-vy49r1zd 379 8 unstimulated unstimulated JJ cord-015569-vy49r1zd 379 9 saliva saliva NN cord-015569-vy49r1zd 379 10 was be VBD cord-015569-vy49r1zd 379 11 almost almost RB cord-015569-vy49r1zd 379 12 the the DT cord-015569-vy49r1zd 379 13 same same JJ cord-015569-vy49r1zd 379 14 as as IN cord-015569-vy49r1zd 379 15 that that IN cord-015569-vy49r1zd 379 16 by by IN cord-015569-vy49r1zd 379 17 infusion infusion NN cord-015569-vy49r1zd 379 18 of of IN cord-015569-vy49r1zd 379 19 water water NN cord-015569-vy49r1zd 379 20 . . . cord-015569-vy49r1zd 380 1 Topical topical JJ cord-015569-vy49r1zd 380 2 anesthesia anesthesia NN cord-015569-vy49r1zd 380 3 of of IN cord-015569-vy49r1zd 380 4 the the DT cord-015569-vy49r1zd 380 5 throat throat NN cord-015569-vy49r1zd 380 6 produced produce VBN cord-015569-vy49r1zd 380 7 loss loss NN cord-015569-vy49r1zd 380 8 of of IN cord-015569-vy49r1zd 380 9 facilitation facilitation NN cord-015569-vy49r1zd 380 10 of of IN cord-015569-vy49r1zd 380 11 voluntary voluntary JJ cord-015569-vy49r1zd 380 12 swallowing swallowing NN cord-015569-vy49r1zd 380 13 by by IN cord-015569-vy49r1zd 380 14 both both DT cord-015569-vy49r1zd 380 15 water water NN cord-015569-vy49r1zd 380 16 infusion infusion NN cord-015569-vy49r1zd 380 17 and and CC cord-015569-vy49r1zd 380 18 unstimulated unstimulated JJ cord-015569-vy49r1zd 380 19 saliva saliva NN cord-015569-vy49r1zd 380 20 infusion infusion NN cord-015569-vy49r1zd 380 21 . . . cord-015569-vy49r1zd 381 1 The the DT cord-015569-vy49r1zd 381 2 similar similar JJ cord-015569-vy49r1zd 381 3 effects effect NNS cord-015569-vy49r1zd 381 4 of of IN cord-015569-vy49r1zd 381 5 water water NN cord-015569-vy49r1zd 381 6 and and CC cord-015569-vy49r1zd 381 7 unstimulated unstimulated JJ cord-015569-vy49r1zd 381 8 saliva saliva NN cord-015569-vy49r1zd 381 9 on on IN cord-015569-vy49r1zd 381 10 voluntary voluntary JJ cord-015569-vy49r1zd 381 11 swallowing swallowing NN cord-015569-vy49r1zd 381 12 suggest suggest VBP cord-015569-vy49r1zd 381 13 that that IN cord-015569-vy49r1zd 381 14 water water NN cord-015569-vy49r1zd 381 15 receptors receptor NNS cord-015569-vy49r1zd 381 16 are be VBP cord-015569-vy49r1zd 381 17 responsible responsible JJ cord-015569-vy49r1zd 381 18 for for IN cord-015569-vy49r1zd 381 19 facilitation facilitation NN cord-015569-vy49r1zd 381 20 of of IN cord-015569-vy49r1zd 381 21 voluntary voluntary JJ cord-015569-vy49r1zd 381 22 swallowing swallowing NN cord-015569-vy49r1zd 381 23 by by IN cord-015569-vy49r1zd 381 24 unstimulated unstimulated JJ cord-015569-vy49r1zd 381 25 saliva saliva NN cord-015569-vy49r1zd 381 26 . . . cord-015569-vy49r1zd 382 1 Since since IN cord-015569-vy49r1zd 382 2 facilitation facilitation NN cord-015569-vy49r1zd 382 3 by by IN cord-015569-vy49r1zd 382 4 water water NN cord-015569-vy49r1zd 382 5 infusion infusion NN cord-015569-vy49r1zd 382 6 appeared appear VBD cord-015569-vy49r1zd 382 7 without without IN cord-015569-vy49r1zd 382 8 mechanical mechanical JJ cord-015569-vy49r1zd 382 9 effect effect NN cord-015569-vy49r1zd 382 10 of of IN cord-015569-vy49r1zd 382 11 infusion infusion NN cord-015569-vy49r1zd 382 12 , , , cord-015569-vy49r1zd 382 13 it -PRON- PRP cord-015569-vy49r1zd 382 14 is be VBZ cord-015569-vy49r1zd 382 15 likely likely JJ cord-015569-vy49r1zd 382 16 that that DT cord-015569-vy49r1zd 382 17 excitation excitation NN cord-015569-vy49r1zd 382 18 of of IN cord-015569-vy49r1zd 382 19 water water NN cord-015569-vy49r1zd 382 20 receptors receptor NNS cord-015569-vy49r1zd 382 21 in in IN cord-015569-vy49r1zd 382 22 the the DT cord-015569-vy49r1zd 382 23 LP LP NNP cord-015569-vy49r1zd 382 24 by by IN cord-015569-vy49r1zd 382 25 a a DT cord-015569-vy49r1zd 382 26 small small JJ cord-015569-vy49r1zd 382 27 amount amount NN cord-015569-vy49r1zd 382 28 of of IN cord-015569-vy49r1zd 382 29 unstimulated unstimulated JJ cord-015569-vy49r1zd 382 30 saliva saliva NN cord-015569-vy49r1zd 382 31 precedes precede VBZ cord-015569-vy49r1zd 382 32 excitation excitation NN cord-015569-vy49r1zd 382 33 of of IN cord-015569-vy49r1zd 382 34 mechanoreceptors mechanoreceptor NNS cord-015569-vy49r1zd 382 35 caused cause VBN cord-015569-vy49r1zd 382 36 by by IN cord-015569-vy49r1zd 382 37 a a DT cord-015569-vy49r1zd 382 38 certain certain JJ cord-015569-vy49r1zd 382 39 amount amount NN cord-015569-vy49r1zd 382 40 of of IN cord-015569-vy49r1zd 382 41 unstimulated unstimulated JJ cord-015569-vy49r1zd 382 42 saliva saliva NN cord-015569-vy49r1zd 382 43 accumulated accumulate VBN cord-015569-vy49r1zd 382 44 in in IN cord-015569-vy49r1zd 382 45 the the DT cord-015569-vy49r1zd 382 46 throat throat NN cord-015569-vy49r1zd 382 47 . . . cord-015569-vy49r1zd 383 1 Excitation excitation NN cord-015569-vy49r1zd 383 2 of of IN cord-015569-vy49r1zd 383 3 water water NN cord-015569-vy49r1zd 383 4 receptors receptor NNS cord-015569-vy49r1zd 383 5 by by IN cord-015569-vy49r1zd 383 6 unstimulated unstimulated JJ cord-015569-vy49r1zd 383 7 saliva saliva NN cord-015569-vy49r1zd 383 8 may may MD cord-015569-vy49r1zd 383 9 initiate initiate VB cord-015569-vy49r1zd 383 10 spontaneous spontaneous JJ cord-015569-vy49r1zd 383 11 swallowing swallowing NN cord-015569-vy49r1zd 383 12 and and CC cord-015569-vy49r1zd 383 13 spontaneous spontaneous JJ cord-015569-vy49r1zd 383 14 swallowing swallowing NN cord-015569-vy49r1zd 383 15 probably probably RB cord-015569-vy49r1zd 383 16 plays play VBZ cord-015569-vy49r1zd 383 17 an an DT cord-015569-vy49r1zd 383 18 important important JJ cord-015569-vy49r1zd 383 19 role role NN cord-015569-vy49r1zd 383 20 in in IN cord-015569-vy49r1zd 383 21 clearance clearance NN cord-015569-vy49r1zd 383 22 of of IN cord-015569-vy49r1zd 383 23 the the DT cord-015569-vy49r1zd 383 24 mouth mouth NN cord-015569-vy49r1zd 383 25 of of IN cord-015569-vy49r1zd 383 26 saliva saliva NN cord-015569-vy49r1zd 383 27 . . . cord-015569-vy49r1zd 384 1 Therefore therefore RB cord-015569-vy49r1zd 384 2 , , , cord-015569-vy49r1zd 384 3 it -PRON- PRP cord-015569-vy49r1zd 384 4 appears appear VBZ cord-015569-vy49r1zd 384 5 that that DT cord-015569-vy49r1zd 384 6 excitation excitation NN cord-015569-vy49r1zd 384 7 of of IN cord-015569-vy49r1zd 384 8 water water NN cord-015569-vy49r1zd 384 9 receptors receptor NNS cord-015569-vy49r1zd 384 10 by by IN cord-015569-vy49r1zd 384 11 unstimulated unstimulated JJ cord-015569-vy49r1zd 384 12 saliva saliva NN cord-015569-vy49r1zd 384 13 may may MD cord-015569-vy49r1zd 384 14 contribute contribute VB cord-015569-vy49r1zd 384 15 to to IN cord-015569-vy49r1zd 384 16 avoidance avoidance NN cord-015569-vy49r1zd 384 17 of of IN cord-015569-vy49r1zd 384 18 aspiration aspiration NN cord-015569-vy49r1zd 384 19 . . . cord-015569-vy49r1zd 385 1 # # $ cord-015569-vy49r1zd 385 2 35 35 CD cord-015569-vy49r1zd 385 3 Peripheral peripheral JJ cord-015569-vy49r1zd 385 4 chemical chemical JJ cord-015569-vy49r1zd 385 5 stimulation stimulation NN cord-015569-vy49r1zd 385 6 to to TO cord-015569-vy49r1zd 385 7 trigger trigger VB cord-015569-vy49r1zd 385 8 the the DT cord-015569-vy49r1zd 385 9 swallowing swallowing NN cord-015569-vy49r1zd 385 10 reflex reflex NN cord-015569-vy49r1zd 385 11 and and CC cord-015569-vy49r1zd 385 12 its -PRON- PRP$ cord-015569-vy49r1zd 385 13 neuronal neuronal JJ cord-015569-vy49r1zd 385 14 mechanisms mechanism NNS cord-015569-vy49r1zd 385 15 in in IN cord-015569-vy49r1zd 385 16 humans human NNS cord-015569-vy49r1zd 386 1 Kensuke Kensuke NNP cord-015569-vy49r1zd 386 2 Kawamoto Kawamoto NNP cord-015569-vy49r1zd 386 3 1 1 CD cord-015569-vy49r1zd 386 4 , , , cord-015569-vy49r1zd 386 5 Takuya Takuya NNP cord-015569-vy49r1zd 386 6 Inoue Inoue NNP cord-015569-vy49r1zd 386 7 1 1 CD cord-015569-vy49r1zd 387 1 , , , cord-015569-vy49r1zd 387 2 Kaya Kaya NNP cord-015569-vy49r1zd 387 3 Narimatsu Narimatsu NNP cord-015569-vy49r1zd 387 4 1 1 CD cord-015569-vy49r1zd 387 5 , , , cord-015569-vy49r1zd 387 6 Yuki Yuki NNP cord-015569-vy49r1zd 387 7 Nakamura Nakamura NNP cord-015569-vy49r1zd 387 8 2 2 CD cord-015569-vy49r1zd 387 9 , , , cord-015569-vy49r1zd 387 10 Makoto Makoto NNP cord-015569-vy49r1zd 387 11 Inoue Inoue NNP cord-015569-vy49r1zd 387 12 2 2 CD cord-015569-vy49r1zd 387 13 , , , cord-015569-vy49r1zd 387 14 Rika Rika NNP cord-015569-vy49r1zd 387 15 Yahagi Yahagi NNP cord-015569-vy49r1zd 387 16 2 2 CD cord-015569-vy49r1zd 387 17 and and CC cord-015569-vy49r1zd 387 18 Yasuyuki Yasuyuki NNP cord-015569-vy49r1zd 387 19 Kitada Kitada NNP cord-015569-vy49r1zd 387 20 3 3 CD cord-015569-vy49r1zd 387 21 1 1 CD cord-015569-vy49r1zd 387 22 Faculty Faculty NNP cord-015569-vy49r1zd 387 23 of of IN cord-015569-vy49r1zd 387 24 Dentistry Dentistry NNP cord-015569-vy49r1zd 387 25 , , , cord-015569-vy49r1zd 387 26 Niigata Niigata NNP cord-015569-vy49r1zd 387 27 University University NNP cord-015569-vy49r1zd 387 28 , , , cord-015569-vy49r1zd 387 29 2 2 CD cord-015569-vy49r1zd 387 30 - - SYM cord-015569-vy49r1zd 387 31 5274 5274 CD cord-015569-vy49r1zd 387 32 Gakkocho Gakkocho NNP cord-015569-vy49r1zd 387 33 - - HYPH cord-015569-vy49r1zd 387 34 dori dori NNP cord-015569-vy49r1zd 387 35 , , , cord-015569-vy49r1zd 387 36 Chuo Chuo NNP cord-015569-vy49r1zd 387 37 - - HYPH cord-015569-vy49r1zd 387 38 ku ku NNP cord-015569-vy49r1zd 387 39 , , , cord-015569-vy49r1zd 387 40 Niigata Niigata NNP cord-015569-vy49r1zd 387 41 951 951 CD cord-015569-vy49r1zd 387 42 - - HYPH cord-015569-vy49r1zd 387 43 8514 8514 CD cord-015569-vy49r1zd 387 44 , , , cord-015569-vy49r1zd 387 45 Japan Japan NNP cord-015569-vy49r1zd 387 46 , , , cord-015569-vy49r1zd 387 47 2 2 CD cord-015569-vy49r1zd 387 48 Division Division NNP cord-015569-vy49r1zd 387 49 of of IN cord-015569-vy49r1zd 387 50 Dysphagia Dysphagia NNP cord-015569-vy49r1zd 387 51 Rehabilitation Rehabilitation NNP cord-015569-vy49r1zd 387 52 , , , cord-015569-vy49r1zd 387 53 Niigata Niigata NNP cord-015569-vy49r1zd 387 54 University University NNP cord-015569-vy49r1zd 387 55 Graduate Graduate NNP cord-015569-vy49r1zd 387 56 School School NNP cord-015569-vy49r1zd 387 57 of of IN cord-015569-vy49r1zd 387 58 Medical Medical NNP cord-015569-vy49r1zd 387 59 and and CC cord-015569-vy49r1zd 387 60 Dental Dental NNP cord-015569-vy49r1zd 387 61 Sciences Sciences NNPS cord-015569-vy49r1zd 387 62 , , , cord-015569-vy49r1zd 387 63 2 2 CD cord-015569-vy49r1zd 387 64 - - SYM cord-015569-vy49r1zd 387 65 5274 5274 CD cord-015569-vy49r1zd 387 66 Gakkocho Gakkocho NNP cord-015569-vy49r1zd 387 67 - - HYPH cord-015569-vy49r1zd 387 68 dori dori NNP cord-015569-vy49r1zd 387 69 , , , cord-015569-vy49r1zd 387 70 Chuo Chuo NNP cord-015569-vy49r1zd 387 71 - - HYPH cord-015569-vy49r1zd 387 72 ku ku NNP cord-015569-vy49r1zd 387 73 , , , cord-015569-vy49r1zd 387 74 Niigata Niigata NNP cord-015569-vy49r1zd 387 75 951 951 CD cord-015569-vy49r1zd 387 76 - - HYPH cord-015569-vy49r1zd 387 77 8514 8514 CD cord-015569-vy49r1zd 387 78 , , , cord-015569-vy49r1zd 387 79 Japan Japan NNP cord-015569-vy49r1zd 387 80 and and CC cord-015569-vy49r1zd 387 81 3 3 CD cord-015569-vy49r1zd 387 82 Morioka Morioka NNP cord-015569-vy49r1zd 387 83 Taste Taste NNP cord-015569-vy49r1zd 387 84 and and CC cord-015569-vy49r1zd 387 85 Swallowing Swallowing NNP cord-015569-vy49r1zd 387 86 Research Research NNP cord-015569-vy49r1zd 387 87 Institute Institute NNP cord-015569-vy49r1zd 387 88 , , , cord-015569-vy49r1zd 387 89 1 1 CD cord-015569-vy49r1zd 387 90 - - SYM cord-015569-vy49r1zd 387 91 15 15 CD cord-015569-vy49r1zd 387 92 - - SYM cord-015569-vy49r1zd 387 93 12 12 CD cord-015569-vy49r1zd 387 94 Higashi Higashi NNP cord-015569-vy49r1zd 387 95 - - HYPH cord-015569-vy49r1zd 387 96 Kuroishino Kuroishino NNP cord-015569-vy49r1zd 387 97 , , , cord-015569-vy49r1zd 387 98 Morioka Morioka NNP cord-015569-vy49r1zd 387 99 020 020 CD cord-015569-vy49r1zd 387 100 - - HYPH cord-015569-vy49r1zd 387 101 0108 0108 CD cord-015569-vy49r1zd 387 102 , , , cord-015569-vy49r1zd 387 103 Japan Japan NNP cord-015569-vy49r1zd 387 104 Initiation Initiation NNP cord-015569-vy49r1zd 387 105 of of IN cord-015569-vy49r1zd 387 106 swallowing swallowing NN cord-015569-vy49r1zd 387 107 is be VBZ cord-015569-vy49r1zd 387 108 mediated mediate VBN cord-015569-vy49r1zd 387 109 by by IN cord-015569-vy49r1zd 387 110 the the DT cord-015569-vy49r1zd 387 111 swallowing swallow VBG cord-015569-vy49r1zd 387 112 central central JJ cord-015569-vy49r1zd 387 113 pattern pattern NN cord-015569-vy49r1zd 387 114 generator generator NN cord-015569-vy49r1zd 387 115 ( ( -LRB- cord-015569-vy49r1zd 387 116 CPG CPG NNP cord-015569-vy49r1zd 387 117 ) ) -RRB- cord-015569-vy49r1zd 387 118 in in IN cord-015569-vy49r1zd 387 119 the the DT cord-015569-vy49r1zd 387 120 brain brain NN cord-015569-vy49r1zd 387 121 stem stem NN cord-015569-vy49r1zd 387 122 . . . cord-015569-vy49r1zd 388 1 Both both DT cord-015569-vy49r1zd 388 2 peripheral peripheral JJ cord-015569-vy49r1zd 388 3 and and CC cord-015569-vy49r1zd 388 4 central central JJ cord-015569-vy49r1zd 388 5 inputs input NNS cord-015569-vy49r1zd 388 6 can can MD cord-015569-vy49r1zd 388 7 activate activate VB cord-015569-vy49r1zd 388 8 the the DT cord-015569-vy49r1zd 388 9 CPG CPG NNP cord-015569-vy49r1zd 388 10 . . . cord-015569-vy49r1zd 389 1 Previous previous JJ cord-015569-vy49r1zd 389 2 studies study NNS cord-015569-vy49r1zd 389 3 demonstrated demonstrate VBD cord-015569-vy49r1zd 389 4 that that IN cord-015569-vy49r1zd 389 5 the the DT cord-015569-vy49r1zd 389 6 ability ability NN cord-015569-vy49r1zd 389 7 to to TO cord-015569-vy49r1zd 389 8 initiate initiate VB cord-015569-vy49r1zd 389 9 repetitive repetitive JJ cord-015569-vy49r1zd 389 10 voluntary voluntary JJ cord-015569-vy49r1zd 389 11 swallowing swallowing NN cord-015569-vy49r1zd 389 12 varies vary VBZ cord-015569-vy49r1zd 389 13 even even RB cord-015569-vy49r1zd 389 14 among among IN cord-015569-vy49r1zd 389 15 healthy healthy JJ cord-015569-vy49r1zd 389 16 humans human NNS cord-015569-vy49r1zd 389 17 and and CC cord-015569-vy49r1zd 389 18 proposed propose VBD cord-015569-vy49r1zd 389 19 that that DT cord-015569-vy49r1zd 389 20 appropriate appropriate JJ cord-015569-vy49r1zd 389 21 chemosensory chemosensory NN cord-015569-vy49r1zd 389 22 inputs input NNS cord-015569-vy49r1zd 389 23 , , , cord-015569-vy49r1zd 389 24 e.g. e.g. RB cord-015569-vy49r1zd 389 25 , , , cord-015569-vy49r1zd 389 26 activation activation NN cord-015569-vy49r1zd 389 27 of of IN cord-015569-vy49r1zd 389 28 water water NN cord-015569-vy49r1zd 389 29 receptors receptor NNS cord-015569-vy49r1zd 389 30 in in IN cord-015569-vy49r1zd 389 31 the the DT cord-015569-vy49r1zd 389 32 pharynx pharynx NN cord-015569-vy49r1zd 389 33 and and CC cord-015569-vy49r1zd 389 34 larynx larynx NN cord-015569-vy49r1zd 389 35 , , , cord-015569-vy49r1zd 389 36 may may MD cord-015569-vy49r1zd 389 37 compensate compensate VB cord-015569-vy49r1zd 389 38 for for IN cord-015569-vy49r1zd 389 39 difficulty difficulty NN cord-015569-vy49r1zd 389 40 in in IN cord-015569-vy49r1zd 389 41 initiation initiation NN cord-015569-vy49r1zd 389 42 of of IN cord-015569-vy49r1zd 389 43 swallowing swallowing NN cord-015569-vy49r1zd 389 44 . . . cord-015569-vy49r1zd 390 1 However however RB cord-015569-vy49r1zd 390 2 , , , cord-015569-vy49r1zd 390 3 whether whether IN cord-015569-vy49r1zd 390 4 variation variation NN cord-015569-vy49r1zd 390 5 also also RB cord-015569-vy49r1zd 390 6 exists exist VBZ cord-015569-vy49r1zd 390 7 in in IN cord-015569-vy49r1zd 390 8 reflexively reflexively RB cord-015569-vy49r1zd 390 9 evoked evoke VBN cord-015569-vy49r1zd 390 10 swallowing swallowing NN cord-015569-vy49r1zd 390 11 is be VBZ cord-015569-vy49r1zd 390 12 unclear unclear JJ cord-015569-vy49r1zd 390 13 , , , cord-015569-vy49r1zd 390 14 and and CC cord-015569-vy49r1zd 390 15 the the DT cord-015569-vy49r1zd 390 16 nature nature NN cord-015569-vy49r1zd 390 17 of of IN cord-015569-vy49r1zd 390 18 interindividual interindividual NNP cord-015569-vy49r1zd 390 19 variation variation NN cord-015569-vy49r1zd 390 20 has have VBZ cord-015569-vy49r1zd 390 21 not not RB cord-015569-vy49r1zd 390 22 been be VBN cord-015569-vy49r1zd 390 23 clarified clarify VBN cord-015569-vy49r1zd 390 24 . . . cord-015569-vy49r1zd 391 1 The the DT cord-015569-vy49r1zd 391 2 aim aim NN cord-015569-vy49r1zd 391 3 of of IN cord-015569-vy49r1zd 391 4 this this DT cord-015569-vy49r1zd 391 5 study study NN cord-015569-vy49r1zd 391 6 was be VBD cord-015569-vy49r1zd 391 7 to to TO cord-015569-vy49r1zd 391 8 investigate investigate VB cord-015569-vy49r1zd 391 9 interindividual interindividual JJ cord-015569-vy49r1zd 391 10 variation variation NN cord-015569-vy49r1zd 391 11 of of IN cord-015569-vy49r1zd 391 12 swallowing swallowing NN cord-015569-vy49r1zd 391 13 initiated initiate VBN cord-015569-vy49r1zd 391 14 by by IN cord-015569-vy49r1zd 391 15 central central JJ cord-015569-vy49r1zd 391 16 and and CC cord-015569-vy49r1zd 391 17 peripheral peripheral JJ cord-015569-vy49r1zd 391 18 inputs input NNS cord-015569-vy49r1zd 391 19 and and CC cord-015569-vy49r1zd 391 20 to to TO cord-015569-vy49r1zd 391 21 clarify clarify VB cord-015569-vy49r1zd 391 22 the the DT cord-015569-vy49r1zd 391 23 neuronal neuronal JJ cord-015569-vy49r1zd 391 24 mechanisms mechanism NNS cord-015569-vy49r1zd 391 25 that that WDT cord-015569-vy49r1zd 391 26 cause cause VBP cord-015569-vy49r1zd 391 27 this this DT cord-015569-vy49r1zd 391 28 variation variation NN cord-015569-vy49r1zd 391 29 . . . cord-015569-vy49r1zd 392 1 Voluntary voluntary JJ cord-015569-vy49r1zd 392 2 and and CC cord-015569-vy49r1zd 392 3 reflexive reflexive JJ cord-015569-vy49r1zd 392 4 swallowing swallowing NN cord-015569-vy49r1zd 392 5 activity activity NN cord-015569-vy49r1zd 392 6 was be VBD cord-015569-vy49r1zd 392 7 recorded record VBN cord-015569-vy49r1zd 392 8 during during IN cord-015569-vy49r1zd 392 9 infusion infusion NN cord-015569-vy49r1zd 392 10 of of IN cord-015569-vy49r1zd 392 11 fluid fluid NN cord-015569-vy49r1zd 392 12 ( ( -LRB- cord-015569-vy49r1zd 392 13 distilled distilled JJ cord-015569-vy49r1zd 392 14 water water NN cord-015569-vy49r1zd 392 15 [ [ -LRB- cord-015569-vy49r1zd 392 16 DW DW NNP cord-015569-vy49r1zd 392 17 ] ] -RRB- cord-015569-vy49r1zd 392 18 or or CC cord-015569-vy49r1zd 392 19 0.3 0.3 CD cord-015569-vy49r1zd 392 20 M m NN cord-015569-vy49r1zd 392 21 NaCl nacl NN cord-015569-vy49r1zd 392 22 solution solution NN cord-015569-vy49r1zd 392 23 ) ) -RRB- cord-015569-vy49r1zd 392 24 into into IN cord-015569-vy49r1zd 392 25 the the DT cord-015569-vy49r1zd 392 26 pharynx pharynx NN cord-015569-vy49r1zd 392 27 and and CC cord-015569-vy49r1zd 392 28 larynx larynx NN cord-015569-vy49r1zd 392 29 at at IN cord-015569-vy49r1zd 392 30 a a DT cord-015569-vy49r1zd 392 31 very very RB cord-015569-vy49r1zd 392 32 low low JJ cord-015569-vy49r1zd 392 33 rate rate NN cord-015569-vy49r1zd 392 34 in in IN cord-015569-vy49r1zd 392 35 20 20 CD cord-015569-vy49r1zd 392 36 healthy healthy JJ cord-015569-vy49r1zd 392 37 volunteers volunteer NNS cord-015569-vy49r1zd 392 38 . . . cord-015569-vy49r1zd 393 1 DW DW NNP cord-015569-vy49r1zd 393 2 and and CC cord-015569-vy49r1zd 393 3 NaCl NaCl NNP cord-015569-vy49r1zd 393 4 were be VBD cord-015569-vy49r1zd 393 5 used use VBN cord-015569-vy49r1zd 393 6 to to TO cord-015569-vy49r1zd 393 7 activate activate VB cord-015569-vy49r1zd 393 8 and and CC cord-015569-vy49r1zd 393 9 inhibit inhibit VB cord-015569-vy49r1zd 393 10 the the DT cord-015569-vy49r1zd 393 11 water water NN cord-015569-vy49r1zd 393 12 receptors receptor NNS cord-015569-vy49r1zd 393 13 , , , cord-015569-vy49r1zd 393 14 the the DT cord-015569-vy49r1zd 393 15 activation activation NN cord-015569-vy49r1zd 393 16 of of IN cord-015569-vy49r1zd 393 17 which which WDT cord-015569-vy49r1zd 393 18 facilitates facilitate VBZ cord-015569-vy49r1zd 393 19 initiation initiation NN cord-015569-vy49r1zd 393 20 of of IN cord-015569-vy49r1zd 393 21 swallowing swallowing NN cord-015569-vy49r1zd 393 22 . . . cord-015569-vy49r1zd 394 1 Swallowing swallow VBG cord-015569-vy49r1zd 394 2 intervals interval NNS cord-015569-vy49r1zd 394 3 ( ( -LRB- cord-015569-vy49r1zd 394 4 SIs sis NN cord-015569-vy49r1zd 394 5 ) ) -RRB- cord-015569-vy49r1zd 394 6 were be VBD cord-015569-vy49r1zd 394 7 measured measure VBN cord-015569-vy49r1zd 394 8 between between IN cord-015569-vy49r1zd 394 9 the the DT cord-015569-vy49r1zd 394 10 fourth fourth JJ cord-015569-vy49r1zd 394 11 and and CC cord-015569-vy49r1zd 394 12 ninth ninth JJ cord-015569-vy49r1zd 394 13 swallows swallow NNS cord-015569-vy49r1zd 394 14 , , , cord-015569-vy49r1zd 394 15 and and CC cord-015569-vy49r1zd 394 16 facilitatory facilitatory NN cord-015569-vy49r1zd 394 17 effects effect NNS cord-015569-vy49r1zd 394 18 ( ( -LRB- cord-015569-vy49r1zd 394 19 FEs FEs NNP cord-015569-vy49r1zd 394 20 ) ) -RRB- cord-015569-vy49r1zd 394 21 were be VBD cord-015569-vy49r1zd 394 22 calculated calculate VBN cord-015569-vy49r1zd 394 23 by by IN cord-015569-vy49r1zd 394 24 subtraction subtraction NN cord-015569-vy49r1zd 394 25 of of IN cord-015569-vy49r1zd 394 26 the the DT cord-015569-vy49r1zd 394 27 SI SI NNP cord-015569-vy49r1zd 394 28 of of IN cord-015569-vy49r1zd 394 29 DW DW NNP cord-015569-vy49r1zd 394 30 from from IN cord-015569-vy49r1zd 394 31 that that DT cord-015569-vy49r1zd 394 32 of of IN cord-015569-vy49r1zd 394 33 NaCl nacl NN cord-015569-vy49r1zd 394 34 . . . cord-015569-vy49r1zd 395 1 There there EX cord-015569-vy49r1zd 395 2 was be VBD cord-015569-vy49r1zd 395 3 a a DT cord-015569-vy49r1zd 395 4 significant significant JJ cord-015569-vy49r1zd 395 5 positive positive JJ cord-015569-vy49r1zd 395 6 correlation correlation NN cord-015569-vy49r1zd 395 7 between between IN cord-015569-vy49r1zd 395 8 SIs si NNS cord-015569-vy49r1zd 395 9 of of IN cord-015569-vy49r1zd 395 10 voluntary voluntary JJ cord-015569-vy49r1zd 395 11 and and CC cord-015569-vy49r1zd 395 12 reflexive reflexive JJ cord-015569-vy49r1zd 395 13 swallowing swallowing NN cord-015569-vy49r1zd 395 14 with with IN cord-015569-vy49r1zd 395 15 NaCl NaCl NNP cord-015569-vy49r1zd 395 16 . . . cord-015569-vy49r1zd 396 1 FEs FEs NNP cord-015569-vy49r1zd 396 2 of of IN cord-015569-vy49r1zd 396 3 both both DT cord-015569-vy49r1zd 396 4 voluntary voluntary JJ cord-015569-vy49r1zd 396 5 and and CC cord-015569-vy49r1zd 396 6 reflexive reflexive JJ cord-015569-vy49r1zd 396 7 swallowing swallowing NN cord-015569-vy49r1zd 396 8 appeared appear VBD cord-015569-vy49r1zd 396 9 strongly strongly RB cord-015569-vy49r1zd 396 10 in in IN cord-015569-vy49r1zd 396 11 subjects subject NNS cord-015569-vy49r1zd 396 12 with with IN cord-015569-vy49r1zd 396 13 longer long JJR cord-015569-vy49r1zd 396 14 SIs sis NN cord-015569-vy49r1zd 396 15 . . . cord-015569-vy49r1zd 397 1 The the DT cord-015569-vy49r1zd 397 2 present present JJ cord-015569-vy49r1zd 397 3 results result NNS cord-015569-vy49r1zd 397 4 suggest suggest VBP cord-015569-vy49r1zd 397 5 that that IN cord-015569-vy49r1zd 397 6 interindividual interindividual JJ cord-015569-vy49r1zd 397 7 variation variation NN cord-015569-vy49r1zd 397 8 in in IN cord-015569-vy49r1zd 397 9 the the DT cord-015569-vy49r1zd 397 10 ability ability NN cord-015569-vy49r1zd 397 11 to to TO cord-015569-vy49r1zd 397 12 initiate initiate VB cord-015569-vy49r1zd 397 13 swallowing swallowing NN cord-015569-vy49r1zd 397 14 depends depend VBZ cord-015569-vy49r1zd 397 15 on on IN cord-015569-vy49r1zd 397 16 the the DT cord-015569-vy49r1zd 397 17 potency potency NN cord-015569-vy49r1zd 397 18 of of IN cord-015569-vy49r1zd 397 19 the the DT cord-015569-vy49r1zd 397 20 swallowing swallow VBG cord-015569-vy49r1zd 397 21 CPG CPG NNP cord-015569-vy49r1zd 397 22 . . . cord-015569-vy49r1zd 398 1 The the DT cord-015569-vy49r1zd 398 2 effects effect NNS cord-015569-vy49r1zd 398 3 of of IN cord-015569-vy49r1zd 398 4 taste taste NN cord-015569-vy49r1zd 398 5 stimuli stimulus NNS cord-015569-vy49r1zd 398 6 on on IN cord-015569-vy49r1zd 398 7 the the DT cord-015569-vy49r1zd 398 8 change change NN cord-015569-vy49r1zd 398 9 in in IN cord-015569-vy49r1zd 398 10 regional regional JJ cord-015569-vy49r1zd 398 11 prefrontal prefrontal JJ cord-015569-vy49r1zd 398 12 cortex cortex NNP cord-015569-vy49r1zd 398 13 blood blood NN cord-015569-vy49r1zd 398 14 flow flow NN cord-015569-vy49r1zd 398 15 ( ( -LRB- cord-015569-vy49r1zd 398 16 rCBF rcbf NN cord-015569-vy49r1zd 398 17 ) ) -RRB- cord-015569-vy49r1zd 398 18 measured measure VBN cord-015569-vy49r1zd 398 19 by by IN cord-015569-vy49r1zd 398 20 multichannel multichannel JJ cord-015569-vy49r1zd 398 21 near near IN cord-015569-vy49r1zd 398 22 infrared infrared JJ cord-015569-vy49r1zd 398 23 spectroscopy spectroscopy NN cord-015569-vy49r1zd 398 24 ( ( -LRB- cord-015569-vy49r1zd 398 25 NIRS NIRS NNP cord-015569-vy49r1zd 398 26 ) ) -RRB- cord-015569-vy49r1zd 398 27 were be VBD cord-015569-vy49r1zd 398 28 evaluated evaluate VBN cord-015569-vy49r1zd 398 29 in in IN cord-015569-vy49r1zd 398 30 10 10 CD cord-015569-vy49r1zd 398 31 healthy healthy JJ cord-015569-vy49r1zd 398 32 women woman NNS cord-015569-vy49r1zd 398 33 volunteers volunteer NNS cord-015569-vy49r1zd 398 34 . . . cord-015569-vy49r1zd 399 1 The the DT cord-015569-vy49r1zd 399 2 test test NN cord-015569-vy49r1zd 399 3 solutions solution NNS cord-015569-vy49r1zd 399 4 were be VBD cord-015569-vy49r1zd 399 5 sucrose sucrose NN cord-015569-vy49r1zd 399 6 , , , cord-015569-vy49r1zd 399 7 NaCl nacl NN cord-015569-vy49r1zd 399 8 , , , cord-015569-vy49r1zd 399 9 citric citric JJ cord-015569-vy49r1zd 399 10 acid acid NN cord-015569-vy49r1zd 399 11 and and CC cord-015569-vy49r1zd 399 12 monosodium monosodium NN cord-015569-vy49r1zd 399 13 glutamate glutamate NN cord-015569-vy49r1zd 399 14 at at IN cord-015569-vy49r1zd 399 15 three three CD cord-015569-vy49r1zd 399 16 different different JJ cord-015569-vy49r1zd 399 17 concentrations concentration NNS cord-015569-vy49r1zd 399 18 each each DT cord-015569-vy49r1zd 399 19 . . . cord-015569-vy49r1zd 400 1 Six six CD cord-015569-vy49r1zd 400 2 pairs pair NNS cord-015569-vy49r1zd 400 3 of of IN cord-015569-vy49r1zd 400 4 source source NN cord-015569-vy49r1zd 400 5 and and CC cord-015569-vy49r1zd 400 6 detector detector NN cord-015569-vy49r1zd 400 7 NIRS nirs NN cord-015569-vy49r1zd 400 8 probes probe NNS cord-015569-vy49r1zd 400 9 were be VBD cord-015569-vy49r1zd 400 10 placed place VBN cord-015569-vy49r1zd 400 11 on on IN cord-015569-vy49r1zd 400 12 the the DT cord-015569-vy49r1zd 400 13 forehead forehead NN cord-015569-vy49r1zd 400 14 with with IN cord-015569-vy49r1zd 400 15 a a DT cord-015569-vy49r1zd 400 16 3 3 CD cord-015569-vy49r1zd 400 17 cm cm NN cord-015569-vy49r1zd 400 18 separation separation NN cord-015569-vy49r1zd 400 19 which which WDT cord-015569-vy49r1zd 400 20 allowed allow VBD cord-015569-vy49r1zd 400 21 the the DT cord-015569-vy49r1zd 400 22 measurement measurement NN cord-015569-vy49r1zd 400 23 of of IN cord-015569-vy49r1zd 400 24 16 16 CD cord-015569-vy49r1zd 400 25 different different JJ cord-015569-vy49r1zd 400 26 channels channel NNS cord-015569-vy49r1zd 400 27 every every DT cord-015569-vy49r1zd 400 28 0.65 0.65 CD cord-015569-vy49r1zd 400 29 sec sec NNP cord-015569-vy49r1zd 400 30 . . . cord-015569-vy49r1zd 401 1 The the DT cord-015569-vy49r1zd 401 2 changes change NNS cord-015569-vy49r1zd 401 3 in in IN cord-015569-vy49r1zd 401 4 oxygenated oxygenated JJ cord-015569-vy49r1zd 401 5 hemoglobin hemoglobin NN cord-015569-vy49r1zd 401 6 ( ( -LRB- cord-015569-vy49r1zd 401 7 oxy oxy NNP cord-015569-vy49r1zd 401 8 - - HYPH cord-015569-vy49r1zd 401 9 Hb Hb NNP cord-015569-vy49r1zd 401 10 ) ) -RRB- cord-015569-vy49r1zd 401 11 , , , cord-015569-vy49r1zd 401 12 which which WDT cord-015569-vy49r1zd 401 13 is be VBZ cord-015569-vy49r1zd 401 14 the the DT cord-015569-vy49r1zd 401 15 most most RBS cord-015569-vy49r1zd 401 16 sensitive sensitive JJ cord-015569-vy49r1zd 401 17 indicator indicator NN cord-015569-vy49r1zd 401 18 of of IN cord-015569-vy49r1zd 401 19 changes change NNS cord-015569-vy49r1zd 401 20 in in IN cord-015569-vy49r1zd 401 21 rCBF rcbf NN cord-015569-vy49r1zd 401 22 , , , cord-015569-vy49r1zd 401 23 were be VBD cord-015569-vy49r1zd 401 24 analyzed analyze VBN cord-015569-vy49r1zd 401 25 . . . cord-015569-vy49r1zd 402 1 Subjects subject NNS cord-015569-vy49r1zd 402 2 were be VBD cord-015569-vy49r1zd 402 3 positioned position VBN cord-015569-vy49r1zd 402 4 in in IN cord-015569-vy49r1zd 402 5 a a DT cord-015569-vy49r1zd 402 6 chair chair NN cord-015569-vy49r1zd 402 7 that that WDT cord-015569-vy49r1zd 402 8 supported support VBD cord-015569-vy49r1zd 402 9 their -PRON- PRP$ cord-015569-vy49r1zd 402 10 back back NN cord-015569-vy49r1zd 402 11 and and CC cord-015569-vy49r1zd 402 12 head head NN cord-015569-vy49r1zd 402 13 while while IN cord-015569-vy49r1zd 402 14 wearing wear VBG cord-015569-vy49r1zd 402 15 a a DT cord-015569-vy49r1zd 402 16 blindfold blindfold NN cord-015569-vy49r1zd 402 17 ( ( -LRB- cord-015569-vy49r1zd 402 18 eyemask eyemask NN cord-015569-vy49r1zd 402 19 ) ) -RRB- cord-015569-vy49r1zd 402 20 and and CC cord-015569-vy49r1zd 402 21 headphones headphone NNS cord-015569-vy49r1zd 402 22 to to TO cord-015569-vy49r1zd 402 23 minimize minimize VB cord-015569-vy49r1zd 402 24 motion motion NN cord-015569-vy49r1zd 402 25 , , , cord-015569-vy49r1zd 402 26 visual visual JJ cord-015569-vy49r1zd 402 27 and and CC cord-015569-vy49r1zd 402 28 auditory auditory JJ cord-015569-vy49r1zd 402 29 disturbances disturbance NNS cord-015569-vy49r1zd 402 30 . . . cord-015569-vy49r1zd 403 1 The the DT cord-015569-vy49r1zd 403 2 entire entire JJ cord-015569-vy49r1zd 403 3 oral oral JJ cord-015569-vy49r1zd 403 4 area area NN cord-015569-vy49r1zd 403 5 was be VBD cord-015569-vy49r1zd 403 6 exposed expose VBN cord-015569-vy49r1zd 403 7 to to IN cord-015569-vy49r1zd 403 8 5 5 CD cord-015569-vy49r1zd 403 9 ml ml NNS cord-015569-vy49r1zd 403 10 of of IN cord-015569-vy49r1zd 403 11 solution solution NN cord-015569-vy49r1zd 403 12 for for IN cord-015569-vy49r1zd 403 13 15 15 CD cord-015569-vy49r1zd 403 14 sec sec NNP cord-015569-vy49r1zd 403 15 applied apply VBD cord-015569-vy49r1zd 403 16 using use VBG cord-015569-vy49r1zd 403 17 a a DT cord-015569-vy49r1zd 403 18 syringe syringe NN cord-015569-vy49r1zd 403 19 and and CC cord-015569-vy49r1zd 403 20 rubber rubber NN cord-015569-vy49r1zd 403 21 tube tube NN cord-015569-vy49r1zd 403 22 positioned position VBN cord-015569-vy49r1zd 403 23 above above IN cord-015569-vy49r1zd 403 24 the the DT cord-015569-vy49r1zd 403 25 head head NN cord-015569-vy49r1zd 403 26 . . . cord-015569-vy49r1zd 404 1 Another another DT cord-015569-vy49r1zd 404 2 solution solution NN cord-015569-vy49r1zd 404 3 was be VBD cord-015569-vy49r1zd 404 4 applied apply VBN cord-015569-vy49r1zd 404 5 after after IN cord-015569-vy49r1zd 404 6 rinsing rinse VBG cord-015569-vy49r1zd 404 7 with with IN cord-015569-vy49r1zd 404 8 deionized deionize VBN cord-015569-vy49r1zd 404 9 water water NN cord-015569-vy49r1zd 404 10 , , , cord-015569-vy49r1zd 404 11 subjects subject NNS cord-015569-vy49r1zd 404 12 were be VBD cord-015569-vy49r1zd 404 13 tested test VBN cord-015569-vy49r1zd 404 14 consecutively consecutively RB cord-015569-vy49r1zd 404 15 for for IN cord-015569-vy49r1zd 404 16 12 12 CD cord-015569-vy49r1zd 404 17 different different JJ cord-015569-vy49r1zd 404 18 solutions solution NNS cord-015569-vy49r1zd 404 19 in in IN cord-015569-vy49r1zd 404 20 random random JJ cord-015569-vy49r1zd 404 21 order order NN cord-015569-vy49r1zd 404 22 . . . cord-015569-vy49r1zd 405 1 Each each DT cord-015569-vy49r1zd 405 2 subject subject NN cord-015569-vy49r1zd 405 3 was be VBD cord-015569-vy49r1zd 405 4 tested test VBN cord-015569-vy49r1zd 405 5 for for IN cord-015569-vy49r1zd 405 6 the the DT cord-015569-vy49r1zd 405 7 same same JJ cord-015569-vy49r1zd 405 8 solution solution NN cord-015569-vy49r1zd 405 9 three three CD cord-015569-vy49r1zd 405 10 times time NNS cord-015569-vy49r1zd 405 11 , , , cord-015569-vy49r1zd 405 12 the the DT cord-015569-vy49r1zd 405 13 data datum NNS cord-015569-vy49r1zd 405 14 were be VBD cord-015569-vy49r1zd 405 15 averaged average VBN cord-015569-vy49r1zd 405 16 and and CC cord-015569-vy49r1zd 405 17 the the DT cord-015569-vy49r1zd 405 18 value value NN cord-015569-vy49r1zd 405 19 for for IN cord-015569-vy49r1zd 405 20 the the DT cord-015569-vy49r1zd 405 21 water water NN cord-015569-vy49r1zd 405 22 test test NN cord-015569-vy49r1zd 405 23 data datum NNS cord-015569-vy49r1zd 405 24 subtracted subtract VBN cord-015569-vy49r1zd 405 25 in in IN cord-015569-vy49r1zd 405 26 order order NN cord-015569-vy49r1zd 405 27 to to TO cord-015569-vy49r1zd 405 28 determine determine VB cord-015569-vy49r1zd 405 29 subjectÕs subjectõs DT cord-015569-vy49r1zd 405 30 value value NN cord-015569-vy49r1zd 405 31 for for IN cord-015569-vy49r1zd 405 32 a a DT cord-015569-vy49r1zd 405 33 given give VBN cord-015569-vy49r1zd 405 34 solution solution NN cord-015569-vy49r1zd 405 35 . . . cord-015569-vy49r1zd 406 1 The the DT cord-015569-vy49r1zd 406 2 taste taste NN cord-015569-vy49r1zd 406 3 hedonic hedonic JJ cord-015569-vy49r1zd 406 4 tone tone NN cord-015569-vy49r1zd 406 5 with with IN cord-015569-vy49r1zd 406 6 a a DT cord-015569-vy49r1zd 406 7 five five CD cord-015569-vy49r1zd 406 8 - - HYPH cord-015569-vy49r1zd 406 9 rating rating NN cord-015569-vy49r1zd 406 10 scale scale NN cord-015569-vy49r1zd 406 11 was be VBD cord-015569-vy49r1zd 406 12 also also RB cord-015569-vy49r1zd 406 13 measured measure VBN cord-015569-vy49r1zd 406 14 for for IN cord-015569-vy49r1zd 406 15 the the DT cord-015569-vy49r1zd 406 16 preference preference NN cord-015569-vy49r1zd 406 17 test test NN cord-015569-vy49r1zd 406 18 . . . cord-015569-vy49r1zd 407 1 Oxy Oxy NNP cord-015569-vy49r1zd 407 2 - - HYPH cord-015569-vy49r1zd 407 3 Hb Hb NNP cord-015569-vy49r1zd 407 4 in in IN cord-015569-vy49r1zd 407 5 all all DT cord-015569-vy49r1zd 407 6 channels channel NNS cord-015569-vy49r1zd 407 7 increased increase VBD cord-015569-vy49r1zd 407 8 during during IN cord-015569-vy49r1zd 407 9 all all DT cord-015569-vy49r1zd 407 10 taste taste NN cord-015569-vy49r1zd 407 11 stimuli stimulus NNS cord-015569-vy49r1zd 407 12 . . . cord-015569-vy49r1zd 408 1 The the DT cord-015569-vy49r1zd 408 2 increases increase NNS cord-015569-vy49r1zd 408 3 in in IN cord-015569-vy49r1zd 408 4 oxy oxy NN cord-015569-vy49r1zd 408 5 - - HYPH cord-015569-vy49r1zd 408 6 Hb Hb NNP cord-015569-vy49r1zd 408 7 and and CC cord-015569-vy49r1zd 408 8 preference preference NN cord-015569-vy49r1zd 408 9 scale scale NN cord-015569-vy49r1zd 408 10 values value NNS cord-015569-vy49r1zd 408 11 showed show VBD cord-015569-vy49r1zd 408 12 significant significant JJ cord-015569-vy49r1zd 408 13 negative negative JJ cord-015569-vy49r1zd 408 14 correlation correlation NN cord-015569-vy49r1zd 408 15 . . . cord-015569-vy49r1zd 409 1 These these DT cord-015569-vy49r1zd 409 2 findings finding NNS cord-015569-vy49r1zd 409 3 indicate indicate VBP cord-015569-vy49r1zd 409 4 that that IN cord-015569-vy49r1zd 409 5 the the DT cord-015569-vy49r1zd 409 6 prefrontal prefrontal NNP cord-015569-vy49r1zd 409 7 cortex cortex NNP cord-015569-vy49r1zd 409 8 activation activation NN cord-015569-vy49r1zd 409 9 evaluated evaluate VBN cord-015569-vy49r1zd 409 10 by by IN cord-015569-vy49r1zd 409 11 NIRS NIRS NNP cord-015569-vy49r1zd 409 12 is be VBZ cord-015569-vy49r1zd 409 13 possibly possibly RB cord-015569-vy49r1zd 409 14 related related JJ cord-015569-vy49r1zd 409 15 to to IN cord-015569-vy49r1zd 409 16 pleasant pleasant JJ cord-015569-vy49r1zd 409 17 or or CC cord-015569-vy49r1zd 409 18 unpleasant unpleasant JJ cord-015569-vy49r1zd 409 19 emotions emotion NNS cord-015569-vy49r1zd 409 20 associated associate VBN cord-015569-vy49r1zd 409 21 with with IN cord-015569-vy49r1zd 409 22 taste taste NN cord-015569-vy49r1zd 409 23 stimuli stimulus NNS cord-015569-vy49r1zd 409 24 . . . cord-015569-vy49r1zd 410 1 We -PRON- PRP cord-015569-vy49r1zd 410 2 receive receive VBP cord-015569-vy49r1zd 410 3 various various JJ cord-015569-vy49r1zd 410 4 different different JJ cord-015569-vy49r1zd 410 5 stimulus stimulus NN cord-015569-vy49r1zd 410 6 modalities modality NNS cord-015569-vy49r1zd 410 7 including include VBG cord-015569-vy49r1zd 410 8 5 5 CD cord-015569-vy49r1zd 410 9 tastants tastant NNS cord-015569-vy49r1zd 410 10 and and CC cord-015569-vy49r1zd 410 11 other other JJ cord-015569-vy49r1zd 410 12 gustatory gustatory JJ cord-015569-vy49r1zd 410 13 and and CC cord-015569-vy49r1zd 410 14 / / SYM cord-015569-vy49r1zd 410 15 or or CC cord-015569-vy49r1zd 410 16 somatosensory somatosensory JJ cord-015569-vy49r1zd 410 17 sensations sensation NNS cord-015569-vy49r1zd 410 18 in in IN cord-015569-vy49r1zd 410 19 eating eat VBG cord-015569-vy49r1zd 410 20 . . . cord-015569-vy49r1zd 411 1 Sensory sensory JJ cord-015569-vy49r1zd 411 2 information information NN cord-015569-vy49r1zd 411 3 from from IN cord-015569-vy49r1zd 411 4 these these DT cord-015569-vy49r1zd 411 5 modalities modality NNS cord-015569-vy49r1zd 411 6 would would MD cord-015569-vy49r1zd 411 7 be be VB cord-015569-vy49r1zd 411 8 integrated integrate VBN cord-015569-vy49r1zd 411 9 and and CC cord-015569-vy49r1zd 411 10 recognized recognize VBN cord-015569-vy49r1zd 411 11 as as IN cord-015569-vy49r1zd 411 12 a a DT cord-015569-vy49r1zd 411 13 ÔFlavorÕ. ôflavorõ. CD cord-015569-vy49r1zd 412 1 It -PRON- PRP cord-015569-vy49r1zd 412 2 is be VBZ cord-015569-vy49r1zd 412 3 useful useful JJ cord-015569-vy49r1zd 412 4 to to TO cord-015569-vy49r1zd 412 5 understand understand VB cord-015569-vy49r1zd 412 6 their -PRON- PRP$ cord-015569-vy49r1zd 412 7 psychophysiological psychophysiological JJ cord-015569-vy49r1zd 412 8 properties property NNS cord-015569-vy49r1zd 412 9 because because IN cord-015569-vy49r1zd 412 10 it -PRON- PRP cord-015569-vy49r1zd 412 11 may may MD cord-015569-vy49r1zd 412 12 help help VB cord-015569-vy49r1zd 412 13 us -PRON- PRP cord-015569-vy49r1zd 412 14 to to TO cord-015569-vy49r1zd 412 15 develop develop VB cord-015569-vy49r1zd 412 16 new new JJ cord-015569-vy49r1zd 412 17 functional functional JJ cord-015569-vy49r1zd 412 18 foods food NNS cord-015569-vy49r1zd 412 19 . . . cord-015569-vy49r1zd 413 1 We -PRON- PRP cord-015569-vy49r1zd 413 2 investigated investigate VBD cord-015569-vy49r1zd 413 3 the the DT cord-015569-vy49r1zd 413 4 effects effect NNS cord-015569-vy49r1zd 413 5 of of IN cord-015569-vy49r1zd 413 6 vanillyl vanillyl JJ cord-015569-vy49r1zd 413 7 butyl butyl NN cord-015569-vy49r1zd 413 8 ether ether NN cord-015569-vy49r1zd 413 9 ( ( -LRB- cord-015569-vy49r1zd 413 10 VBE VBE NNP cord-015569-vy49r1zd 413 11 ) ) -RRB- cord-015569-vy49r1zd 413 12 , , , cord-015569-vy49r1zd 413 13 l l NNP cord-015569-vy49r1zd 413 14 - - HYPH cord-015569-vy49r1zd 413 15 menthol menthol NNP cord-015569-vy49r1zd 413 16 ( ( -LRB- cord-015569-vy49r1zd 413 17 LM LM NNP cord-015569-vy49r1zd 413 18 ) ) -RRB- cord-015569-vy49r1zd 413 19 and and CC cord-015569-vy49r1zd 413 20 carbonated carbonated JJ cord-015569-vy49r1zd 413 21 water water NN cord-015569-vy49r1zd 413 22 ( ( -LRB- cord-015569-vy49r1zd 413 23 CW CW NNP cord-015569-vy49r1zd 413 24 ) ) -RRB- cord-015569-vy49r1zd 413 25 to to IN cord-015569-vy49r1zd 413 26 the the DT cord-015569-vy49r1zd 413 27 arousal arousal NN cord-015569-vy49r1zd 413 28 level level NN cord-015569-vy49r1zd 413 29 of of IN cord-015569-vy49r1zd 413 30 12 12 CD cord-015569-vy49r1zd 413 31 healthy healthy JJ cord-015569-vy49r1zd 413 32 subjects subject NNS cord-015569-vy49r1zd 413 33 . . . cord-015569-vy49r1zd 414 1 These these DT cord-015569-vy49r1zd 414 2 3 3 CD cord-015569-vy49r1zd 414 3 stimuli stimulus NNS cord-015569-vy49r1zd 414 4 were be VBD cord-015569-vy49r1zd 414 5 used use VBN cord-015569-vy49r1zd 414 6 as as IN cord-015569-vy49r1zd 414 7 hot hot JJ cord-015569-vy49r1zd 414 8 , , , cord-015569-vy49r1zd 414 9 cold cold JJ cord-015569-vy49r1zd 414 10 , , , cord-015569-vy49r1zd 414 11 tingling tingle VBG cord-015569-vy49r1zd 414 12 stimulus stimulus NN cord-015569-vy49r1zd 414 13 respectively respectively RB cord-015569-vy49r1zd 414 14 . . . cord-015569-vy49r1zd 415 1 The the DT cord-015569-vy49r1zd 415 2 results result NNS cord-015569-vy49r1zd 415 3 of of IN cord-015569-vy49r1zd 415 4 Contingent Contingent NNP cord-015569-vy49r1zd 415 5 Negative negative JJ cord-015569-vy49r1zd 415 6 Variation Variation NNP cord-015569-vy49r1zd 415 7 showed show VBD cord-015569-vy49r1zd 415 8 that that IN cord-015569-vy49r1zd 415 9 VBE VBE NNP cord-015569-vy49r1zd 415 10 , , , cord-015569-vy49r1zd 415 11 LM LM NNP cord-015569-vy49r1zd 415 12 and and CC cord-015569-vy49r1zd 415 13 CW CW NNP cord-015569-vy49r1zd 415 14 increased increase VBD cord-015569-vy49r1zd 415 15 subjectÕs subjectõs JJ cord-015569-vy49r1zd 415 16 arousal arousal NN cord-015569-vy49r1zd 415 17 level level NN cord-015569-vy49r1zd 415 18 just just RB cord-015569-vy49r1zd 415 19 after after IN cord-015569-vy49r1zd 415 20 ingested ingest VBN cord-015569-vy49r1zd 415 21 by by IN cord-015569-vy49r1zd 415 22 aqueous aqueous JJ cord-015569-vy49r1zd 415 23 solution solution NN cord-015569-vy49r1zd 415 24 whereas whereas IN cord-015569-vy49r1zd 415 25 no no DT cord-015569-vy49r1zd 415 26 significant significant JJ cord-015569-vy49r1zd 415 27 change change NN cord-015569-vy49r1zd 415 28 was be VBD cord-015569-vy49r1zd 415 29 observed observe VBN cord-015569-vy49r1zd 415 30 after after IN cord-015569-vy49r1zd 415 31 the the DT cord-015569-vy49r1zd 415 32 water water NN cord-015569-vy49r1zd 415 33 ingestion ingestion NN cord-015569-vy49r1zd 415 34 . . . cord-015569-vy49r1zd 416 1 The the DT cord-015569-vy49r1zd 416 2 increase increase NN cord-015569-vy49r1zd 416 3 of of IN cord-015569-vy49r1zd 416 4 the the DT cord-015569-vy49r1zd 416 5 arousal arousal NN cord-015569-vy49r1zd 416 6 level level NN cord-015569-vy49r1zd 416 7 still still RB cord-015569-vy49r1zd 416 8 remained remain VBD cord-015569-vy49r1zd 416 9 for for IN cord-015569-vy49r1zd 416 10 20 20 CD cord-015569-vy49r1zd 416 11 min min NN cord-015569-vy49r1zd 416 12 after after IN cord-015569-vy49r1zd 416 13 ingesting ingest VBG cord-015569-vy49r1zd 416 14 VBE VBE NNP cord-015569-vy49r1zd 416 15 and and CC cord-015569-vy49r1zd 416 16 LM LM NNP cord-015569-vy49r1zd 416 17 . . . cord-015569-vy49r1zd 417 1 On on IN cord-015569-vy49r1zd 417 2 the the DT cord-015569-vy49r1zd 417 3 other other JJ cord-015569-vy49r1zd 417 4 hand hand NN cord-015569-vy49r1zd 417 5 , , , cord-015569-vy49r1zd 417 6 the the DT cord-015569-vy49r1zd 417 7 arousal arousal NN cord-015569-vy49r1zd 417 8 level level NN cord-015569-vy49r1zd 417 9 of of IN cord-015569-vy49r1zd 417 10 20 20 CD cord-015569-vy49r1zd 417 11 min min NN cord-015569-vy49r1zd 417 12 after after IN cord-015569-vy49r1zd 417 13 ingesting ingest VBG cord-015569-vy49r1zd 417 14 CW CW NNP cord-015569-vy49r1zd 417 15 decreased decrease VBD cord-015569-vy49r1zd 417 16 to to IN cord-015569-vy49r1zd 417 17 the the DT cord-015569-vy49r1zd 417 18 same same JJ cord-015569-vy49r1zd 417 19 level level NN cord-015569-vy49r1zd 417 20 as as IN cord-015569-vy49r1zd 417 21 before before IN cord-015569-vy49r1zd 417 22 ingestion ingestion NN cord-015569-vy49r1zd 417 23 . . . cord-015569-vy49r1zd 418 1 Apart apart RB cord-015569-vy49r1zd 418 2 of of IN cord-015569-vy49r1zd 418 3 the the DT cord-015569-vy49r1zd 418 4 subjects subject NNS cord-015569-vy49r1zd 418 5 were be VBD cord-015569-vy49r1zd 418 6 asked ask VBN cord-015569-vy49r1zd 418 7 to to TO cord-015569-vy49r1zd 418 8 rate rate VB cord-015569-vy49r1zd 418 9 the the DT cord-015569-vy49r1zd 418 10 general general JJ cord-015569-vy49r1zd 418 11 stimulus stimulus NN cord-015569-vy49r1zd 418 12 intensity intensity NN cord-015569-vy49r1zd 418 13 by by IN cord-015569-vy49r1zd 418 14 9 9 CD cord-015569-vy49r1zd 418 15 point point NN cord-015569-vy49r1zd 418 16 likert likert NNP cord-015569-vy49r1zd 418 17 scale scale NN cord-015569-vy49r1zd 418 18 . . . cord-015569-vy49r1zd 419 1 All all DT cord-015569-vy49r1zd 419 2 samples sample NNS cord-015569-vy49r1zd 419 3 including include VBG cord-015569-vy49r1zd 419 4 water water NN cord-015569-vy49r1zd 419 5 showed show VBD cord-015569-vy49r1zd 419 6 maximum maximum JJ cord-015569-vy49r1zd 419 7 intensity intensity NN cord-015569-vy49r1zd 419 8 just just RB cord-015569-vy49r1zd 419 9 after after IN cord-015569-vy49r1zd 419 10 ingestion ingestion NN cord-015569-vy49r1zd 419 11 and and CC cord-015569-vy49r1zd 419 12 decreased decrease VBD cord-015569-vy49r1zd 419 13 with with IN cord-015569-vy49r1zd 419 14 time time NN cord-015569-vy49r1zd 419 15 course course NN cord-015569-vy49r1zd 419 16 . . . cord-015569-vy49r1zd 420 1 However however RB cord-015569-vy49r1zd 420 2 , , , cord-015569-vy49r1zd 420 3 the the DT cord-015569-vy49r1zd 420 4 significant significant JJ cord-015569-vy49r1zd 420 5 increase increase NN cord-015569-vy49r1zd 420 6 of of IN cord-015569-vy49r1zd 420 7 the the DT cord-015569-vy49r1zd 420 8 stimulus stimulus NN cord-015569-vy49r1zd 420 9 intensity intensity NN cord-015569-vy49r1zd 420 10 still still RB cord-015569-vy49r1zd 420 11 remained remain VBD cord-015569-vy49r1zd 420 12 for for IN cord-015569-vy49r1zd 420 13 20 20 CD cord-015569-vy49r1zd 420 14 min min NN cord-015569-vy49r1zd 420 15 after after IN cord-015569-vy49r1zd 420 16 ingesting ingest VBG cord-015569-vy49r1zd 420 17 3 3 CD cord-015569-vy49r1zd 420 18 stimulus stimulus NN cord-015569-vy49r1zd 420 19 solutions solution NNS cord-015569-vy49r1zd 420 20 . . . cord-015569-vy49r1zd 421 1 These these DT cord-015569-vy49r1zd 421 2 discrepancies discrepancy NNS cord-015569-vy49r1zd 421 3 between between IN cord-015569-vy49r1zd 421 4 the the DT cord-015569-vy49r1zd 421 5 arousal arousal NN cord-015569-vy49r1zd 421 6 level level NN cord-015569-vy49r1zd 421 7 and and CC cord-015569-vy49r1zd 421 8 subjective subjective JJ cord-015569-vy49r1zd 421 9 stimulus stimulus NN cord-015569-vy49r1zd 421 10 intensity intensity NN cord-015569-vy49r1zd 421 11 of of IN cord-015569-vy49r1zd 421 12 CW CW NNP cord-015569-vy49r1zd 421 13 suggest suggest VBP cord-015569-vy49r1zd 421 14 that that IN cord-015569-vy49r1zd 421 15 only only JJ cord-015569-vy49r1zd 421 16 stimulus stimulus NN cord-015569-vy49r1zd 421 17 intensity intensity NN cord-015569-vy49r1zd 421 18 itself -PRON- PRP cord-015569-vy49r1zd 421 19 can can MD cord-015569-vy49r1zd 421 20 not not RB cord-015569-vy49r1zd 421 21 explain explain VB cord-015569-vy49r1zd 421 22 the the DT cord-015569-vy49r1zd 421 23 change change NN cord-015569-vy49r1zd 421 24 of of IN cord-015569-vy49r1zd 421 25 the the DT cord-015569-vy49r1zd 421 26 arousal arousal NN cord-015569-vy49r1zd 421 27 level level NN cord-015569-vy49r1zd 421 28 . . . cord-015569-vy49r1zd 422 1 In in IN cord-015569-vy49r1zd 422 2 order order NN cord-015569-vy49r1zd 422 3 to to TO cord-015569-vy49r1zd 422 4 understand understand VB cord-015569-vy49r1zd 422 5 the the DT cord-015569-vy49r1zd 422 6 property property NN cord-015569-vy49r1zd 422 7 of of IN cord-015569-vy49r1zd 422 8 each each DT cord-015569-vy49r1zd 422 9 stimulus stimulus NN cord-015569-vy49r1zd 422 10 , , , cord-015569-vy49r1zd 422 11 we -PRON- PRP cord-015569-vy49r1zd 422 12 need need VBP cord-015569-vy49r1zd 422 13 to to TO cord-015569-vy49r1zd 422 14 look look VB cord-015569-vy49r1zd 422 15 each each DT cord-015569-vy49r1zd 422 16 stimulus stimulus NN cord-015569-vy49r1zd 422 17 into into IN cord-015569-vy49r1zd 422 18 detail detail NN cord-015569-vy49r1zd 422 19 in in IN cord-015569-vy49r1zd 422 20 the the DT cord-015569-vy49r1zd 422 21 derived derive VBN cord-015569-vy49r1zd 422 22 modality modality NN cord-015569-vy49r1zd 422 23 of of IN cord-015569-vy49r1zd 422 24 the the DT cord-015569-vy49r1zd 422 25 sensation sensation NN cord-015569-vy49r1zd 422 26 , , , cord-015569-vy49r1zd 422 27 intensity intensity NN cord-015569-vy49r1zd 422 28 , , , cord-015569-vy49r1zd 422 29 timing timing NN cord-015569-vy49r1zd 422 30 of of IN cord-015569-vy49r1zd 422 31 appearance appearance NN cord-015569-vy49r1zd 422 32 . . . cord-015569-vy49r1zd 423 1 We -PRON- PRP cord-015569-vy49r1zd 423 2 had have VBD cord-015569-vy49r1zd 423 3 reported report VBN cord-015569-vy49r1zd 423 4 that that IN cord-015569-vy49r1zd 423 5 umami umami NN cord-015569-vy49r1zd 423 6 taste taste NN cord-015569-vy49r1zd 423 7 induced induce VBN cord-015569-vy49r1zd 423 8 sustained sustain VBD cord-015569-vy49r1zd 423 9 saliva saliva NN cord-015569-vy49r1zd 423 10 secretion secretion NN cord-015569-vy49r1zd 423 11 . . . cord-015569-vy49r1zd 424 1 In in IN cord-015569-vy49r1zd 424 2 this this DT cord-015569-vy49r1zd 424 3 study study NN cord-015569-vy49r1zd 424 4 , , , cord-015569-vy49r1zd 424 5 to to TO cord-015569-vy49r1zd 424 6 investigate investigate VB cord-015569-vy49r1zd 424 7 the the DT cord-015569-vy49r1zd 424 8 effect effect NN cord-015569-vy49r1zd 424 9 of of IN cord-015569-vy49r1zd 424 10 repetitive repetitive JJ cord-015569-vy49r1zd 424 11 taste taste NN cord-015569-vy49r1zd 424 12 stimulation stimulation NN cord-015569-vy49r1zd 424 13 on on IN cord-015569-vy49r1zd 424 14 saliva saliva NN cord-015569-vy49r1zd 424 15 secretion secretion NN cord-015569-vy49r1zd 424 16 , , , cord-015569-vy49r1zd 424 17 we -PRON- PRP cord-015569-vy49r1zd 424 18 compared compare VBD cord-015569-vy49r1zd 424 19 the the DT cord-015569-vy49r1zd 424 20 saliva saliva NN cord-015569-vy49r1zd 424 21 weight weight NN cord-015569-vy49r1zd 424 22 secreted secrete VBN cord-015569-vy49r1zd 424 23 by by IN cord-015569-vy49r1zd 424 24 single single JJ cord-015569-vy49r1zd 424 25 taste taste NN cord-015569-vy49r1zd 424 26 stimulation stimulation NN cord-015569-vy49r1zd 424 27 ( ( -LRB- cord-015569-vy49r1zd 424 28 Single single JJ cord-015569-vy49r1zd 424 29 Stimulation stimulation NN cord-015569-vy49r1zd 424 30 methods method NNS cord-015569-vy49r1zd 424 31 ; ; : cord-015569-vy49r1zd 424 32 SS ss NN cord-015569-vy49r1zd 424 33 ) ) -RRB- cord-015569-vy49r1zd 424 34 with with IN cord-015569-vy49r1zd 424 35 repetitive repetitive JJ cord-015569-vy49r1zd 424 36 taste taste NN cord-015569-vy49r1zd 424 37 stimulation stimulation NN cord-015569-vy49r1zd 424 38 ( ( -LRB- cord-015569-vy49r1zd 424 39 Repetitive repetitive JJ cord-015569-vy49r1zd 424 40 Stimulation stimulation NN cord-015569-vy49r1zd 424 41 method method NN cord-015569-vy49r1zd 424 42 ; ; : cord-015569-vy49r1zd 424 43 RS RS NNP cord-015569-vy49r1zd 424 44 ) ) -RRB- cord-015569-vy49r1zd 424 45 , , , cord-015569-vy49r1zd 424 46 using use VBG cord-015569-vy49r1zd 424 47 fourteen fourteen CD cord-015569-vy49r1zd 424 48 healthy healthy JJ cord-015569-vy49r1zd 424 49 adult adult NN cord-015569-vy49r1zd 424 50 subjects subject NNS cord-015569-vy49r1zd 424 51 . . . cord-015569-vy49r1zd 425 1 In in IN cord-015569-vy49r1zd 425 2 SS SS NNP cord-015569-vy49r1zd 425 3 , , , cord-015569-vy49r1zd 425 4 the the DT cord-015569-vy49r1zd 425 5 subjects subject NNS cord-015569-vy49r1zd 425 6 sprayed spray VBD cord-015569-vy49r1zd 425 7 the the DT cord-015569-vy49r1zd 425 8 taste taste NN cord-015569-vy49r1zd 425 9 solution solution NN cord-015569-vy49r1zd 425 10 ( ( -LRB- cord-015569-vy49r1zd 425 11 approx approx NN cord-015569-vy49r1zd 425 12 . . . cord-015569-vy49r1zd 425 13 0.25 0.25 CD cord-015569-vy49r1zd 425 14 ml ml LS cord-015569-vy49r1zd 425 15 ) ) -RRB- cord-015569-vy49r1zd 425 16 using use VBG cord-015569-vy49r1zd 425 17 a a DT cord-015569-vy49r1zd 425 18 spray spray NN cord-015569-vy49r1zd 425 19 bottle bottle NN cord-015569-vy49r1zd 425 20 into into IN cord-015569-vy49r1zd 425 21 the the DT cord-015569-vy49r1zd 425 22 mouth mouth NN cord-015569-vy49r1zd 425 23 , , , cord-015569-vy49r1zd 425 24 and and CC cord-015569-vy49r1zd 425 25 held hold VBD cord-015569-vy49r1zd 425 26 for for IN cord-015569-vy49r1zd 425 27 30 30 CD cord-015569-vy49r1zd 425 28 seconds second NNS cord-015569-vy49r1zd 425 29 and and CC cord-015569-vy49r1zd 425 30 spat spit VBD cord-015569-vy49r1zd 425 31 the the DT cord-015569-vy49r1zd 425 32 whole whole JJ cord-015569-vy49r1zd 425 33 saliva saliva NN cord-015569-vy49r1zd 425 34 into into IN cord-015569-vy49r1zd 425 35 cups cup NNS cord-015569-vy49r1zd 425 36 at at IN cord-015569-vy49r1zd 425 37 every every DT cord-015569-vy49r1zd 425 38 30 30 CD cord-015569-vy49r1zd 425 39 second second NN cord-015569-vy49r1zd 425 40 for for IN cord-015569-vy49r1zd 425 41 10 10 CD cord-015569-vy49r1zd 425 42 minutes minute NNS cord-015569-vy49r1zd 425 43 . . . cord-015569-vy49r1zd 426 1 In in IN cord-015569-vy49r1zd 426 2 RS rs NN cord-015569-vy49r1zd 426 3 , , , cord-015569-vy49r1zd 426 4 the the DT cord-015569-vy49r1zd 426 5 subjects subject NNS cord-015569-vy49r1zd 426 6 sprayed spray VBD cord-015569-vy49r1zd 426 7 the the DT cord-015569-vy49r1zd 426 8 taste taste NN cord-015569-vy49r1zd 426 9 solution solution NN cord-015569-vy49r1zd 426 10 into into IN cord-015569-vy49r1zd 426 11 the the DT cord-015569-vy49r1zd 426 12 mouth mouth NN cord-015569-vy49r1zd 426 13 , , , cord-015569-vy49r1zd 426 14 and and CC cord-015569-vy49r1zd 426 15 held hold VBD cord-015569-vy49r1zd 426 16 for for IN cord-015569-vy49r1zd 426 17 30 30 CD cord-015569-vy49r1zd 426 18 seconds second NNS cord-015569-vy49r1zd 426 19 , , , cord-015569-vy49r1zd 426 20 then then RB cord-015569-vy49r1zd 426 21 , , , cord-015569-vy49r1zd 426 22 spat spit VBD cord-015569-vy49r1zd 426 23 the the DT cord-015569-vy49r1zd 426 24 whole whole JJ cord-015569-vy49r1zd 426 25 saliva saliva NN cord-015569-vy49r1zd 426 26 into into IN cord-015569-vy49r1zd 426 27 cup cup NN cord-015569-vy49r1zd 426 28 , , , cord-015569-vy49r1zd 426 29 and and CC cord-015569-vy49r1zd 426 30 rested rest VBD cord-015569-vy49r1zd 426 31 for for IN cord-015569-vy49r1zd 426 32 1 1 CD cord-015569-vy49r1zd 426 33 minute minute NN cord-015569-vy49r1zd 426 34 until until IN cord-015569-vy49r1zd 426 35 the the DT cord-015569-vy49r1zd 426 36 next next JJ cord-015569-vy49r1zd 426 37 stimulation stimulation NN cord-015569-vy49r1zd 426 38 . . . cord-015569-vy49r1zd 427 1 After after IN cord-015569-vy49r1zd 427 2 this this DT cord-015569-vy49r1zd 427 3 procedure procedure NN cord-015569-vy49r1zd 427 4 was be VBD cord-015569-vy49r1zd 427 5 repeated repeat VBN cord-015569-vy49r1zd 427 6 ten ten CD cord-015569-vy49r1zd 427 7 times time NNS cord-015569-vy49r1zd 427 8 , , , cord-015569-vy49r1zd 427 9 the the DT cord-015569-vy49r1zd 427 10 subject subject NN cord-015569-vy49r1zd 427 11 performed perform VBD cord-015569-vy49r1zd 427 12 the the DT cord-015569-vy49r1zd 427 13 same same JJ cord-015569-vy49r1zd 427 14 procedure procedure NN cord-015569-vy49r1zd 427 15 as as IN cord-015569-vy49r1zd 427 16 SS SS NNP cord-015569-vy49r1zd 427 17 . . . cord-015569-vy49r1zd 428 1 The the DT cord-015569-vy49r1zd 428 2 stimuli stimulus NNS cord-015569-vy49r1zd 428 3 were be VBD cord-015569-vy49r1zd 428 4 100 100 CD cord-015569-vy49r1zd 428 5 mM mm CD cord-015569-vy49r1zd 428 6 monosodium monosodium NN cord-015569-vy49r1zd 428 7 glutamate glutamate NN cord-015569-vy49r1zd 428 8 ( ( -LRB- cord-015569-vy49r1zd 428 9 MSG MSG NNP cord-015569-vy49r1zd 428 10 ) ) -RRB- cord-015569-vy49r1zd 428 11 ( ( -LRB- cord-015569-vy49r1zd 428 12 umami umami NN cord-015569-vy49r1zd 428 13 ) ) -RRB- cord-015569-vy49r1zd 428 14 , , , cord-015569-vy49r1zd 428 15 3.8 3.8 CD cord-015569-vy49r1zd 428 16 mM mm CD cord-015569-vy49r1zd 428 17 citric citric NN cord-015569-vy49r1zd 428 18 acid acid NN cord-015569-vy49r1zd 428 19 ( ( -LRB- cord-015569-vy49r1zd 428 20 sour sour JJ cord-015569-vy49r1zd 428 21 ) ) -RRB- cord-015569-vy49r1zd 428 22 and and CC cord-015569-vy49r1zd 428 23 440 440 CD cord-015569-vy49r1zd 428 24 mM mm CD cord-015569-vy49r1zd 428 25 xylitol xylitol NN cord-015569-vy49r1zd 428 26 ( ( -LRB- cord-015569-vy49r1zd 428 27 sweet sweet NNP cord-015569-vy49r1zd 428 28 ) ) -RRB- cord-015569-vy49r1zd 428 29 , , , cord-015569-vy49r1zd 428 30 which which WDT cord-015569-vy49r1zd 428 31 had have VBD cord-015569-vy49r1zd 428 32 ÔmoderateÕ ÔmoderateÕ `` cord-015569-vy49r1zd 428 33 taste taste VB cord-015569-vy49r1zd 428 34 intensity intensity NN cord-015569-vy49r1zd 428 35 on on IN cord-015569-vy49r1zd 428 36 a a DT cord-015569-vy49r1zd 428 37 labeled label VBN cord-015569-vy49r1zd 428 38 magnitude magnitude NN cord-015569-vy49r1zd 428 39 scale scale NN cord-015569-vy49r1zd 428 40 . . . cord-015569-vy49r1zd 429 1 During during IN cord-015569-vy49r1zd 429 2 the the DT cord-015569-vy49r1zd 429 3 repetitive repetitive JJ cord-015569-vy49r1zd 429 4 stimulation stimulation NN cord-015569-vy49r1zd 429 5 in in IN cord-015569-vy49r1zd 429 6 the the DT cord-015569-vy49r1zd 429 7 RS rs NN cord-015569-vy49r1zd 429 8 of of IN cord-015569-vy49r1zd 429 9 MSG MSG NNP cord-015569-vy49r1zd 429 10 , , , cord-015569-vy49r1zd 429 11 the the DT cord-015569-vy49r1zd 429 12 salivary salivary NN cord-015569-vy49r1zd 429 13 flow flow NN cord-015569-vy49r1zd 429 14 was be VBD cord-015569-vy49r1zd 429 15 reduced reduce VBN cord-015569-vy49r1zd 429 16 gradually gradually RB cord-015569-vy49r1zd 429 17 according accord VBG cord-015569-vy49r1zd 429 18 to to IN cord-015569-vy49r1zd 429 19 the the DT cord-015569-vy49r1zd 429 20 decrease decrease NN cord-015569-vy49r1zd 429 21 of of IN cord-015569-vy49r1zd 429 22 umami umami NN cord-015569-vy49r1zd 429 23 taste taste NN cord-015569-vy49r1zd 429 24 intensity intensity NN cord-015569-vy49r1zd 429 25 by by IN cord-015569-vy49r1zd 429 26 adaptation adaptation NN cord-015569-vy49r1zd 429 27 . . . cord-015569-vy49r1zd 430 1 However however RB cord-015569-vy49r1zd 430 2 , , , cord-015569-vy49r1zd 430 3 the the DT cord-015569-vy49r1zd 430 4 MSG MSG NNP cord-015569-vy49r1zd 430 5 stimulation stimulation NN cord-015569-vy49r1zd 430 6 caused cause VBD cord-015569-vy49r1zd 430 7 a a DT cord-015569-vy49r1zd 430 8 sustained sustain VBN cord-015569-vy49r1zd 430 9 salivary salivary JJ cord-015569-vy49r1zd 430 10 secretion secretion NN cord-015569-vy49r1zd 430 11 after after IN cord-015569-vy49r1zd 430 12 repetitive repetitive JJ cord-015569-vy49r1zd 430 13 stimulation stimulation NN cord-015569-vy49r1zd 430 14 , , , cord-015569-vy49r1zd 430 15 and and CC cord-015569-vy49r1zd 430 16 there there EX cord-015569-vy49r1zd 430 17 was be VBD cord-015569-vy49r1zd 430 18 no no DT cord-015569-vy49r1zd 430 19 significant significant JJ cord-015569-vy49r1zd 430 20 difference difference NN cord-015569-vy49r1zd 430 21 in in IN cord-015569-vy49r1zd 430 22 the the DT cord-015569-vy49r1zd 430 23 10 10 CD cord-015569-vy49r1zd 430 24 minutes minute NNS cord-015569-vy49r1zd 430 25 saliva saliva NN cord-015569-vy49r1zd 430 26 between between IN cord-015569-vy49r1zd 430 27 SS SS NNP cord-015569-vy49r1zd 430 28 and and CC cord-015569-vy49r1zd 430 29 RS rs NN cord-015569-vy49r1zd 430 30 . . . cord-015569-vy49r1zd 431 1 Thus thus RB cord-015569-vy49r1zd 431 2 , , , cord-015569-vy49r1zd 431 3 the the DT cord-015569-vy49r1zd 431 4 repetitive repetitive JJ cord-015569-vy49r1zd 431 5 umami umami NN cord-015569-vy49r1zd 431 6 stimulation stimulation NN cord-015569-vy49r1zd 431 7 did do VBD cord-015569-vy49r1zd 431 8 not not RB cord-015569-vy49r1zd 431 9 reduce reduce VB cord-015569-vy49r1zd 431 10 saliva saliva NN cord-015569-vy49r1zd 431 11 secretion secretion NN cord-015569-vy49r1zd 431 12 and and CC cord-015569-vy49r1zd 431 13 could could MD cord-015569-vy49r1zd 431 14 produce produce VB cord-015569-vy49r1zd 431 15 sustained sustain VBN cord-015569-vy49r1zd 431 16 salivary salivary JJ cord-015569-vy49r1zd 431 17 secretion secretion NN cord-015569-vy49r1zd 431 18 . . . cord-015569-vy49r1zd 432 1 There there EX cord-015569-vy49r1zd 432 2 was be VBD cord-015569-vy49r1zd 432 3 no no DT cord-015569-vy49r1zd 432 4 adaptation adaptation NN cord-015569-vy49r1zd 432 5 in in IN cord-015569-vy49r1zd 432 6 RS rs NN cord-015569-vy49r1zd 432 7 of of IN cord-015569-vy49r1zd 432 8 citric citric JJ cord-015569-vy49r1zd 432 9 acid acid NN cord-015569-vy49r1zd 432 10 and and CC cord-015569-vy49r1zd 432 11 xylitol xylitol NN cord-015569-vy49r1zd 432 12 , , , cord-015569-vy49r1zd 432 13 and and CC cord-015569-vy49r1zd 432 14 the the DT cord-015569-vy49r1zd 432 15 saliva saliva NN cord-015569-vy49r1zd 432 16 secretion secretion NN cord-015569-vy49r1zd 432 17 pattern pattern NN cord-015569-vy49r1zd 432 18 of of IN cord-015569-vy49r1zd 432 19 RS rs NN cord-015569-vy49r1zd 432 20 was be VBD cord-015569-vy49r1zd 432 21 similar similar JJ cord-015569-vy49r1zd 432 22 to to IN cord-015569-vy49r1zd 432 23 that that DT cord-015569-vy49r1zd 432 24 of of IN cord-015569-vy49r1zd 432 25 SS SS NNP cord-015569-vy49r1zd 432 26 , , , cord-015569-vy49r1zd 432 27 with with IN cord-015569-vy49r1zd 432 28 less less JJR cord-015569-vy49r1zd 432 29 saliva saliva NN cord-015569-vy49r1zd 432 30 secretion secretion NN cord-015569-vy49r1zd 432 31 than than IN cord-015569-vy49r1zd 432 32 MSG MSG NNP cord-015569-vy49r1zd 432 33 . . . cord-015569-vy49r1zd 433 1 Dried dry VBN cord-015569-vy49r1zd 433 2 - - HYPH cord-015569-vy49r1zd 433 3 bonito bonito FW cord-015569-vy49r1zd 433 4 ( ( -LRB- cord-015569-vy49r1zd 433 5 DB DB NNP cord-015569-vy49r1zd 433 6 ) ) -RRB- cord-015569-vy49r1zd 433 7 dashi dashi NN cord-015569-vy49r1zd 433 8 is be VBZ cord-015569-vy49r1zd 433 9 a a DT cord-015569-vy49r1zd 433 10 traditional traditional JJ cord-015569-vy49r1zd 433 11 Japanese japanese JJ cord-015569-vy49r1zd 433 12 broth broth NN cord-015569-vy49r1zd 433 13 that that WDT cord-015569-vy49r1zd 433 14 enhances enhance VBZ cord-015569-vy49r1zd 433 15 palatability palatability NN cord-015569-vy49r1zd 433 16 of of IN cord-015569-vy49r1zd 433 17 various various JJ cord-015569-vy49r1zd 433 18 cuisines cuisine NNS cord-015569-vy49r1zd 433 19 due due JJ cord-015569-vy49r1zd 433 20 to to IN cord-015569-vy49r1zd 433 21 its -PRON- PRP$ cord-015569-vy49r1zd 433 22 specific specific JJ cord-015569-vy49r1zd 433 23 flavor flavor NN cord-015569-vy49r1zd 433 24 . . . cord-015569-vy49r1zd 434 1 DB DB NNP cord-015569-vy49r1zd 434 2 dashi dashi NN cord-015569-vy49r1zd 434 3 contains contain VBZ cord-015569-vy49r1zd 434 4 many many JJ cord-015569-vy49r1zd 434 5 components component NNS cord-015569-vy49r1zd 434 6 , , , cord-015569-vy49r1zd 434 7 such such JJ cord-015569-vy49r1zd 434 8 as as IN cord-015569-vy49r1zd 434 9 histidine histidine NN cord-015569-vy49r1zd 434 10 , , , cord-015569-vy49r1zd 434 11 lactate lactate NN cord-015569-vy49r1zd 434 12 , , , cord-015569-vy49r1zd 434 13 inosinate inosinate NNP cord-015569-vy49r1zd 434 14 , , , cord-015569-vy49r1zd 434 15 minerals mineral NNS cord-015569-vy49r1zd 434 16 , , , cord-015569-vy49r1zd 434 17 and and CC cord-015569-vy49r1zd 434 18 proteins protein NNS cord-015569-vy49r1zd 434 19 . . . cord-015569-vy49r1zd 435 1 Ingestion ingestion NN cord-015569-vy49r1zd 435 2 of of IN cord-015569-vy49r1zd 435 3 DB DB NNP cord-015569-vy49r1zd 435 4 dashi dashi NN cord-015569-vy49r1zd 435 5 has have VBZ cord-015569-vy49r1zd 435 6 been be VBN cord-015569-vy49r1zd 435 7 reported report VBN cord-015569-vy49r1zd 435 8 to to TO cord-015569-vy49r1zd 435 9 have have VB cord-015569-vy49r1zd 435 10 various various JJ cord-015569-vy49r1zd 435 11 physiological physiological JJ cord-015569-vy49r1zd 435 12 functions function NNS cord-015569-vy49r1zd 435 13 , , , cord-015569-vy49r1zd 435 14 e.g. e.g. RB cord-015569-vy49r1zd 435 15 , , , cord-015569-vy49r1zd 435 16 effectiveness effectiveness NN cord-015569-vy49r1zd 435 17 against against IN cord-015569-vy49r1zd 435 18 physical physical JJ cord-015569-vy49r1zd 435 19 and and CC cord-015569-vy49r1zd 435 20 mental mental JJ cord-015569-vy49r1zd 435 21 fatigues fatigue NNS cord-015569-vy49r1zd 435 22 , , , cord-015569-vy49r1zd 435 23 enhancement enhancement NN cord-015569-vy49r1zd 435 24 of of IN cord-015569-vy49r1zd 435 25 peripheral peripheral JJ cord-015569-vy49r1zd 435 26 blood blood NN cord-015569-vy49r1zd 435 27 flow flow NN cord-015569-vy49r1zd 435 28 , , , cord-015569-vy49r1zd 435 29 and and CC cord-015569-vy49r1zd 435 30 suppression suppression NN cord-015569-vy49r1zd 435 31 of of IN cord-015569-vy49r1zd 435 32 oxidative oxidative JJ cord-015569-vy49r1zd 435 33 stress stress NN cord-015569-vy49r1zd 435 34 . . . cord-015569-vy49r1zd 436 1 In in IN cord-015569-vy49r1zd 436 2 this this DT cord-015569-vy49r1zd 436 3 study study NN cord-015569-vy49r1zd 436 4 , , , cord-015569-vy49r1zd 436 5 we -PRON- PRP cord-015569-vy49r1zd 436 6 investigated investigate VBD cord-015569-vy49r1zd 436 7 the the DT cord-015569-vy49r1zd 436 8 effects effect NNS cord-015569-vy49r1zd 436 9 of of IN cord-015569-vy49r1zd 436 10 DB db NN cord-015569-vy49r1zd 436 11 dashi dashi NN cord-015569-vy49r1zd 436 12 on on IN cord-015569-vy49r1zd 436 13 gastric gastric JJ cord-015569-vy49r1zd 436 14 electrical electrical JJ cord-015569-vy49r1zd 436 15 activity activity NN cord-015569-vy49r1zd 436 16 and and CC cord-015569-vy49r1zd 436 17 hunger hunger NN cord-015569-vy49r1zd 436 18 - - HYPH cord-015569-vy49r1zd 436 19 satiety satiety NN cord-015569-vy49r1zd 436 20 states state NNS cord-015569-vy49r1zd 436 21 in in IN cord-015569-vy49r1zd 436 22 healthy healthy JJ cord-015569-vy49r1zd 436 23 Japanese japanese JJ cord-015569-vy49r1zd 436 24 males male NNS cord-015569-vy49r1zd 436 25 . . . cord-015569-vy49r1zd 437 1 We -PRON- PRP cord-015569-vy49r1zd 437 2 performed perform VBD cord-015569-vy49r1zd 437 3 a a DT cord-015569-vy49r1zd 437 4 randomized randomized JJ cord-015569-vy49r1zd 437 5 crossover crossover NN cord-015569-vy49r1zd 437 6 study study NN cord-015569-vy49r1zd 437 7 for for IN cord-015569-vy49r1zd 437 8 19 19 CD cord-015569-vy49r1zd 437 9 healthy healthy JJ cord-015569-vy49r1zd 437 10 males male NNS cord-015569-vy49r1zd 437 11 ( ( -LRB- cord-015569-vy49r1zd 437 12 21.5 21.5 CD cord-015569-vy49r1zd 437 13 ± ± CD cord-015569-vy49r1zd 437 14 0.5 0.5 CD cord-015569-vy49r1zd 437 15 yr yr NN cord-015569-vy49r1zd 437 16 ) ) -RRB- cord-015569-vy49r1zd 437 17 . . . cord-015569-vy49r1zd 438 1 Subjects subject NNS cord-015569-vy49r1zd 438 2 were be VBD cord-015569-vy49r1zd 438 3 fasted fast VBN cord-015569-vy49r1zd 438 4 for for IN cord-015569-vy49r1zd 438 5 at at RB cord-015569-vy49r1zd 438 6 least least RBS cord-015569-vy49r1zd 438 7 10 10 CD cord-015569-vy49r1zd 438 8 h h NN cord-015569-vy49r1zd 438 9 , , , cord-015569-vy49r1zd 438 10 and and CC cord-015569-vy49r1zd 438 11 all all DT cord-015569-vy49r1zd 438 12 measurements measurement NNS cord-015569-vy49r1zd 438 13 were be VBD cord-015569-vy49r1zd 438 14 performed perform VBN cord-015569-vy49r1zd 438 15 in in IN cord-015569-vy49r1zd 438 16 the the DT cord-015569-vy49r1zd 438 17 morning morning NN cord-015569-vy49r1zd 438 18 . . . cord-015569-vy49r1zd 439 1 Before before IN cord-015569-vy49r1zd 439 2 and and CC cord-015569-vy49r1zd 439 3 just just RB cord-015569-vy49r1zd 439 4 after after IN cord-015569-vy49r1zd 439 5 a a DT cord-015569-vy49r1zd 439 6 single single JJ cord-015569-vy49r1zd 439 7 ingestion ingestion NN cord-015569-vy49r1zd 439 8 of of IN cord-015569-vy49r1zd 439 9 150 150 CD cord-015569-vy49r1zd 439 10 ml ml NNS cord-015569-vy49r1zd 439 11 of of IN cord-015569-vy49r1zd 439 12 DB DB NNP cord-015569-vy49r1zd 439 13 dashi dashi NNS cord-015569-vy49r1zd 439 14 ( ( -LRB- cord-015569-vy49r1zd 439 15 ' ' '' cord-015569-vy49r1zd 439 16 ' ' '' cord-015569-vy49r1zd 439 17 Hondzukuri Hondzukuri NNP cord-015569-vy49r1zd 439 18 Ichiban Ichiban NNP cord-015569-vy49r1zd 439 19 - - HYPH cord-015569-vy49r1zd 439 20 dashi dashi NNP cord-015569-vy49r1zd 439 21 Katsuo Katsuo NNP cord-015569-vy49r1zd 439 22 ' ' '' cord-015569-vy49r1zd 439 23 ' ' '' cord-015569-vy49r1zd 439 24 , , , cord-015569-vy49r1zd 439 25 Ajinomoto Ajinomoto NNP cord-015569-vy49r1zd 439 26 Co. Co. NNP cord-015569-vy49r1zd 439 27 , , , cord-015569-vy49r1zd 439 28 Inc. Inc. NNP cord-015569-vy49r1zd 439 29 , , , cord-015569-vy49r1zd 439 30 Japan Japan NNP cord-015569-vy49r1zd 439 31 ) ) -RRB- cord-015569-vy49r1zd 439 32 or or CC cord-015569-vy49r1zd 439 33 energy energy NN cord-015569-vy49r1zd 439 34 adjusted adjust VBN cord-015569-vy49r1zd 439 35 water water NN cord-015569-vy49r1zd 439 36 as as IN cord-015569-vy49r1zd 439 37 a a DT cord-015569-vy49r1zd 439 38 control control NN cord-015569-vy49r1zd 439 39 , , , cord-015569-vy49r1zd 439 40 gastric gastric JJ cord-015569-vy49r1zd 439 41 myoelectrical myoelectrical JJ cord-015569-vy49r1zd 439 42 activity activity NN cord-015569-vy49r1zd 439 43 was be VBD cord-015569-vy49r1zd 439 44 measured measure VBN cord-015569-vy49r1zd 439 45 by by IN cord-015569-vy49r1zd 439 46 electrogastrography electrogastrography NN cord-015569-vy49r1zd 439 47 for for IN cord-015569-vy49r1zd 439 48 20 20 CD cord-015569-vy49r1zd 439 49 min min NN cord-015569-vy49r1zd 439 50 . . . cord-015569-vy49r1zd 440 1 Subjective subjective JJ cord-015569-vy49r1zd 440 2 motivation motivation NN cord-015569-vy49r1zd 440 3 to to TO cord-015569-vy49r1zd 440 4 eat eat VB cord-015569-vy49r1zd 440 5 ( ( -LRB- cord-015569-vy49r1zd 440 6 hunger hunger NN cord-015569-vy49r1zd 440 7 and and CC cord-015569-vy49r1zd 440 8 satiety satiety NN cord-015569-vy49r1zd 440 9 ) ) -RRB- cord-015569-vy49r1zd 440 10 was be VBD cord-015569-vy49r1zd 440 11 rated rate VBN cord-015569-vy49r1zd 440 12 by by IN cord-015569-vy49r1zd 440 13 visual visual JJ cord-015569-vy49r1zd 440 14 analogue analogue NN cord-015569-vy49r1zd 440 15 scales scale NNS cord-015569-vy49r1zd 440 16 before before RB cord-015569-vy49r1zd 440 17 , , , cord-015569-vy49r1zd 440 18 immediately immediately RB cord-015569-vy49r1zd 440 19 after after RB cord-015569-vy49r1zd 440 20 , , , cord-015569-vy49r1zd 440 21 and and CC cord-015569-vy49r1zd 440 22 35 35 CD cord-015569-vy49r1zd 440 23 min min NN cord-015569-vy49r1zd 440 24 after after IN cord-015569-vy49r1zd 440 25 the the DT cord-015569-vy49r1zd 440 26 ingestion ingestion NN cord-015569-vy49r1zd 440 27 . . . cord-015569-vy49r1zd 441 1 Ingestion ingestion NN cord-015569-vy49r1zd 441 2 of of IN cord-015569-vy49r1zd 441 3 DB DB NNP cord-015569-vy49r1zd 441 4 dashi dashi NNS cord-015569-vy49r1zd 441 5 significantly significantly RB cord-015569-vy49r1zd 441 6 increased increase VBD cord-015569-vy49r1zd 441 7 both both DT cord-015569-vy49r1zd 441 8 electrogastrographic electrogastrographic NNP cord-015569-vy49r1zd 441 9 normogastric normogastric NNP cord-015569-vy49r1zd 441 10 power power NN cord-015569-vy49r1zd 441 11 and and CC cord-015569-vy49r1zd 441 12 percentage percentage NN cord-015569-vy49r1zd 441 13 in in IN cord-015569-vy49r1zd 441 14 postprandial postprandial JJ cord-015569-vy49r1zd 441 15 state state NN cord-015569-vy49r1zd 441 16 . . . cord-015569-vy49r1zd 442 1 In in IN cord-015569-vy49r1zd 442 2 addition addition NN cord-015569-vy49r1zd 442 3 , , , cord-015569-vy49r1zd 442 4 DB DB NNP cord-015569-vy49r1zd 442 5 dashi dashi NN cord-015569-vy49r1zd 442 6 produced produce VBD cord-015569-vy49r1zd 442 7 higher high JJR cord-015569-vy49r1zd 442 8 satiety satiety NN cord-015569-vy49r1zd 442 9 sensations sensation NNS cord-015569-vy49r1zd 442 10 at at IN cord-015569-vy49r1zd 442 11 35 35 CD cord-015569-vy49r1zd 442 12 min min NN cord-015569-vy49r1zd 442 13 after after IN cord-015569-vy49r1zd 442 14 the the DT cord-015569-vy49r1zd 442 15 ingestion ingestion NN cord-015569-vy49r1zd 442 16 , , , cord-015569-vy49r1zd 442 17 compared compare VBN cord-015569-vy49r1zd 442 18 to to IN cord-015569-vy49r1zd 442 19 the the DT cord-015569-vy49r1zd 442 20 control control NN cord-015569-vy49r1zd 442 21 diet diet NN cord-015569-vy49r1zd 442 22 . . . cord-015569-vy49r1zd 443 1 In in IN cord-015569-vy49r1zd 443 2 conclusion conclusion NN cord-015569-vy49r1zd 443 3 , , , cord-015569-vy49r1zd 443 4 DB DB NNP cord-015569-vy49r1zd 443 5 dashi dashi NN cord-015569-vy49r1zd 443 6 intake intake NN cord-015569-vy49r1zd 443 7 enhances enhance VBZ cord-015569-vy49r1zd 443 8 the the DT cord-015569-vy49r1zd 443 9 gastric gastric JJ cord-015569-vy49r1zd 443 10 motility motility NN cord-015569-vy49r1zd 443 11 and and CC cord-015569-vy49r1zd 443 12 satiety satiety NN cord-015569-vy49r1zd 443 13 in in IN cord-015569-vy49r1zd 443 14 humans human NNS cord-015569-vy49r1zd 443 15 . . . cord-015569-vy49r1zd 444 1 We -PRON- PRP cord-015569-vy49r1zd 444 2 usually usually RB cord-015569-vy49r1zd 444 3 take take VBP cord-015569-vy49r1zd 444 4 sweet sweet JJ cord-015569-vy49r1zd 444 5 foods food NNS cord-015569-vy49r1zd 444 6 with with IN cord-015569-vy49r1zd 444 7 drinking drink VBG cord-015569-vy49r1zd 444 8 tea tea NN cord-015569-vy49r1zd 444 9 or or CC cord-015569-vy49r1zd 444 10 coffee coffee NN cord-015569-vy49r1zd 444 11 not not RB cord-015569-vy49r1zd 444 12 only only RB cord-015569-vy49r1zd 444 13 to to TO cord-015569-vy49r1zd 444 14 increase increase VB cord-015569-vy49r1zd 444 15 nutrition nutrition NN cord-015569-vy49r1zd 444 16 but but CC cord-015569-vy49r1zd 444 17 also also RB cord-015569-vy49r1zd 444 18 to to TO cord-015569-vy49r1zd 444 19 produce produce VB cord-015569-vy49r1zd 444 20 feelings feeling NNS cord-015569-vy49r1zd 444 21 of of IN cord-015569-vy49r1zd 444 22 pleasantness pleasantness NN cord-015569-vy49r1zd 444 23 and and CC cord-015569-vy49r1zd 444 24 restfulness restfulness NN cord-015569-vy49r1zd 444 25 that that WDT cord-015569-vy49r1zd 444 26 belong belong VBP cord-015569-vy49r1zd 444 27 category category NN cord-015569-vy49r1zd 444 28 of of IN cord-015569-vy49r1zd 444 29 emotion emotion NN cord-015569-vy49r1zd 444 30 . . . cord-015569-vy49r1zd 445 1 When when WRB cord-015569-vy49r1zd 445 2 we -PRON- PRP cord-015569-vy49r1zd 445 3 take take VBP cord-015569-vy49r1zd 445 4 sweet sweet JJ cord-015569-vy49r1zd 445 5 foods food NNS cord-015569-vy49r1zd 445 6 , , , cord-015569-vy49r1zd 445 7 comfortable comfortable JJ cord-015569-vy49r1zd 445 8 audio audio JJ cord-015569-vy49r1zd 445 9 - - HYPH cord-015569-vy49r1zd 445 10 visual visual JJ cord-015569-vy49r1zd 445 11 environments environment NNS cord-015569-vy49r1zd 445 12 , , , cord-015569-vy49r1zd 445 13 e.g. e.g. RB cord-015569-vy49r1zd 445 14 consonant consonant JJ cord-015569-vy49r1zd 445 15 interior interior JJ cord-015569-vy49r1zd 445 16 decoration decoration NN cord-015569-vy49r1zd 445 17 , , , cord-015569-vy49r1zd 445 18 good good JJ cord-015569-vy49r1zd 445 19 music music NN cord-015569-vy49r1zd 445 20 and and CC cord-015569-vy49r1zd 445 21 fine fine JJ cord-015569-vy49r1zd 445 22 view view NN cord-015569-vy49r1zd 445 23 may may MD cord-015569-vy49r1zd 445 24 increase increase VB cord-015569-vy49r1zd 445 25 feelings feeling NNS cord-015569-vy49r1zd 445 26 of of IN cord-015569-vy49r1zd 445 27 deliciousness deliciousness NN cord-015569-vy49r1zd 445 28 . . . cord-015569-vy49r1zd 446 1 Thus thus RB cord-015569-vy49r1zd 446 2 , , , cord-015569-vy49r1zd 446 3 it -PRON- PRP cord-015569-vy49r1zd 446 4 is be VBZ cord-015569-vy49r1zd 446 5 hypothesize hypothesize VB cord-015569-vy49r1zd 446 6 that that IN cord-015569-vy49r1zd 446 7 environmental environmental JJ cord-015569-vy49r1zd 446 8 factors factor NNS cord-015569-vy49r1zd 446 9 modify modify VBP cord-015569-vy49r1zd 446 10 feelings feeling NNS cord-015569-vy49r1zd 446 11 of of IN cord-015569-vy49r1zd 446 12 deliciousness deliciousness NN cord-015569-vy49r1zd 446 13 . . . cord-015569-vy49r1zd 447 1 Comprehensive comprehensive JJ cord-015569-vy49r1zd 447 2 delicious delicious JJ cord-015569-vy49r1zd 447 3 feelings feeling NNS cord-015569-vy49r1zd 447 4 during during IN cord-015569-vy49r1zd 447 5 having have VBG cord-015569-vy49r1zd 447 6 sweet sweet JJ cord-015569-vy49r1zd 447 7 foods food NNS cord-015569-vy49r1zd 447 8 might may MD cord-015569-vy49r1zd 447 9 be be VB cord-015569-vy49r1zd 447 10 effectively effectively RB cord-015569-vy49r1zd 447 11 produced produce VBN cord-015569-vy49r1zd 447 12 in in IN cord-015569-vy49r1zd 447 13 the the DT cord-015569-vy49r1zd 447 14 comfortable comfortable JJ cord-015569-vy49r1zd 447 15 environments environment NNS cord-015569-vy49r1zd 447 16 by by IN cord-015569-vy49r1zd 447 17 integration integration NN cord-015569-vy49r1zd 447 18 of of IN cord-015569-vy49r1zd 447 19 various various JJ cord-015569-vy49r1zd 447 20 palatable palatable JJ cord-015569-vy49r1zd 447 21 sensory sensory JJ cord-015569-vy49r1zd 447 22 perceptions perception NNS cord-015569-vy49r1zd 447 23 . . . cord-015569-vy49r1zd 448 1 Electroencephalograms Electroencephalograms NNP cord-015569-vy49r1zd 448 2 ( ( -LRB- cord-015569-vy49r1zd 448 3 EEGs eeg NNS cord-015569-vy49r1zd 448 4 ) ) -RRB- cord-015569-vy49r1zd 448 5 were be VBD cord-015569-vy49r1zd 448 6 recorded record VBN cord-015569-vy49r1zd 448 7 from from IN cord-015569-vy49r1zd 448 8 frontal frontal JJ cord-015569-vy49r1zd 448 9 region region NN cord-015569-vy49r1zd 448 10 of of IN cord-015569-vy49r1zd 448 11 the the DT cord-015569-vy49r1zd 448 12 scalp scalp NN cord-015569-vy49r1zd 448 13 of of IN cord-015569-vy49r1zd 448 14 healthy healthy JJ cord-015569-vy49r1zd 448 15 participants participant NNS cord-015569-vy49r1zd 448 16 under under IN cord-015569-vy49r1zd 448 17 virtual virtual JJ cord-015569-vy49r1zd 448 18 scenes scene NNS cord-015569-vy49r1zd 448 19 of of IN cord-015569-vy49r1zd 448 20 tearoom tearoom NN cord-015569-vy49r1zd 448 21 and and CC cord-015569-vy49r1zd 448 22 construction construction NN cord-015569-vy49r1zd 448 23 work work NN cord-015569-vy49r1zd 448 24 , , , cord-015569-vy49r1zd 448 25 respectively respectively RB cord-015569-vy49r1zd 448 26 . . . cord-015569-vy49r1zd 449 1 The the DT cord-015569-vy49r1zd 449 2 participants participant NNS cord-015569-vy49r1zd 449 3 were be VBD cord-015569-vy49r1zd 449 4 asked ask VBN cord-015569-vy49r1zd 449 5 to to TO cord-015569-vy49r1zd 449 6 rate rate VB cord-015569-vy49r1zd 449 7 deliciousness deliciousness NN cord-015569-vy49r1zd 449 8 after after IN cord-015569-vy49r1zd 449 9 the the DT cord-015569-vy49r1zd 449 10 recordings recording NNS cord-015569-vy49r1zd 449 11 . . . cord-015569-vy49r1zd 450 1 Frequency frequency NN cord-015569-vy49r1zd 450 2 analyses analysis NNS cord-015569-vy49r1zd 450 3 were be VBD cord-015569-vy49r1zd 450 4 performed perform VBN cord-015569-vy49r1zd 450 5 from from IN cord-015569-vy49r1zd 450 6 the the DT cord-015569-vy49r1zd 450 7 EEGs eeg NNS cord-015569-vy49r1zd 450 8 . . . cord-015569-vy49r1zd 451 1 During during IN cord-015569-vy49r1zd 451 2 having have VBG cord-015569-vy49r1zd 451 3 the the DT cord-015569-vy49r1zd 451 4 foods food NNS cord-015569-vy49r1zd 451 5 , , , cord-015569-vy49r1zd 451 6 occupancy occupancy NN cord-015569-vy49r1zd 451 7 rates rate NNS cord-015569-vy49r1zd 451 8 of of IN cord-015569-vy49r1zd 451 9 beta beta JJ cord-015569-vy49r1zd 451 10 frequency frequency NN cord-015569-vy49r1zd 451 11 band band NN cord-015569-vy49r1zd 451 12 between between IN cord-015569-vy49r1zd 451 13 tearoom tearoom NN cord-015569-vy49r1zd 451 14 scenes scene NNS cord-015569-vy49r1zd 451 15 and and CC cord-015569-vy49r1zd 451 16 construction construction NN cord-015569-vy49r1zd 451 17 work work NN cord-015569-vy49r1zd 451 18 scenes scene NNS cord-015569-vy49r1zd 451 19 were be VBD cord-015569-vy49r1zd 451 20 markedly markedly RB cord-015569-vy49r1zd 451 21 different different JJ cord-015569-vy49r1zd 451 22 , , , cord-015569-vy49r1zd 451 23 but but CC cord-015569-vy49r1zd 451 24 not not RB cord-015569-vy49r1zd 451 25 in in IN cord-015569-vy49r1zd 451 26 other other JJ cord-015569-vy49r1zd 451 27 frequency frequency NN cord-015569-vy49r1zd 451 28 bands band NNS cord-015569-vy49r1zd 451 29 . . . cord-015569-vy49r1zd 452 1 During during IN cord-015569-vy49r1zd 452 2 having have VBG cord-015569-vy49r1zd 452 3 no no DT cord-015569-vy49r1zd 452 4 food food NN cord-015569-vy49r1zd 452 5 , , , cord-015569-vy49r1zd 452 6 in in IN cord-015569-vy49r1zd 452 7 contrast contrast NN cord-015569-vy49r1zd 452 8 , , , cord-015569-vy49r1zd 452 9 there there EX cord-015569-vy49r1zd 452 10 was be VBD cord-015569-vy49r1zd 452 11 no no DT cord-015569-vy49r1zd 452 12 difference difference NN cord-015569-vy49r1zd 452 13 of of IN cord-015569-vy49r1zd 452 14 occupancy occupancy NN cord-015569-vy49r1zd 452 15 rates rate NNS cord-015569-vy49r1zd 452 16 in in IN cord-015569-vy49r1zd 452 17 respective respective JJ cord-015569-vy49r1zd 452 18 frequency frequency NN cord-015569-vy49r1zd 452 19 bands band NNS cord-015569-vy49r1zd 452 20 between between IN cord-015569-vy49r1zd 452 21 the the DT cord-015569-vy49r1zd 452 22 two two CD cord-015569-vy49r1zd 452 23 different different JJ cord-015569-vy49r1zd 452 24 scenes scene NNS cord-015569-vy49r1zd 452 25 . . . cord-015569-vy49r1zd 453 1 With with IN cord-015569-vy49r1zd 453 2 regard regard NN cord-015569-vy49r1zd 453 3 to to IN cord-015569-vy49r1zd 453 4 deliciousness deliciousness NN cord-015569-vy49r1zd 453 5 during during IN cord-015569-vy49r1zd 453 6 having have VBG cord-015569-vy49r1zd 453 7 sweet sweet JJ cord-015569-vy49r1zd 453 8 foods food NNS cord-015569-vy49r1zd 453 9 , , , cord-015569-vy49r1zd 453 10 all all DT cord-015569-vy49r1zd 453 11 participants participant NNS cord-015569-vy49r1zd 453 12 rated rate VBD cord-015569-vy49r1zd 453 13 high high JJ cord-015569-vy49r1zd 453 14 scores score NNS cord-015569-vy49r1zd 453 15 under under IN cord-015569-vy49r1zd 453 16 the the DT cord-015569-vy49r1zd 453 17 scenes scene NNS cord-015569-vy49r1zd 453 18 of of IN cord-015569-vy49r1zd 453 19 tearoom tearoom NN cord-015569-vy49r1zd 453 20 than than IN cord-015569-vy49r1zd 453 21 those those DT cord-015569-vy49r1zd 453 22 under under IN cord-015569-vy49r1zd 453 23 the the DT cord-015569-vy49r1zd 453 24 scenes scene NNS cord-015569-vy49r1zd 453 25 of of IN cord-015569-vy49r1zd 453 26 construction construction NN cord-015569-vy49r1zd 453 27 work work NN cord-015569-vy49r1zd 453 28 . . . cord-015569-vy49r1zd 454 1 Interestingly interestingly RB cord-015569-vy49r1zd 454 2 , , , cord-015569-vy49r1zd 454 3 there there EX cord-015569-vy49r1zd 454 4 is be VBZ cord-015569-vy49r1zd 454 5 a a DT cord-015569-vy49r1zd 454 6 positive positive JJ cord-015569-vy49r1zd 454 7 correlation correlation NN cord-015569-vy49r1zd 454 8 between between IN cord-015569-vy49r1zd 454 9 occupancy occupancy NN cord-015569-vy49r1zd 454 10 rates rate NNS cord-015569-vy49r1zd 454 11 of of IN cord-015569-vy49r1zd 454 12 beta beta JJ cord-015569-vy49r1zd 454 13 frequency frequency NN cord-015569-vy49r1zd 454 14 band band NN cord-015569-vy49r1zd 454 15 and and CC cord-015569-vy49r1zd 454 16 scores score NNS cord-015569-vy49r1zd 454 17 of of IN cord-015569-vy49r1zd 454 18 deliciousness deliciousness NN cord-015569-vy49r1zd 454 19 . . . cord-015569-vy49r1zd 455 1 These these DT cord-015569-vy49r1zd 455 2 findings finding NNS cord-015569-vy49r1zd 455 3 suggest suggest VBP cord-015569-vy49r1zd 455 4 that that IN cord-015569-vy49r1zd 455 5 comfortable comfortable JJ cord-015569-vy49r1zd 455 6 audio audio JJ cord-015569-vy49r1zd 455 7 - - HYPH cord-015569-vy49r1zd 455 8 visual visual JJ cord-015569-vy49r1zd 455 9 environments environment NNS cord-015569-vy49r1zd 455 10 play play VBP cord-015569-vy49r1zd 455 11 an an DT cord-015569-vy49r1zd 455 12 important important JJ cord-015569-vy49r1zd 455 13 role role NN cord-015569-vy49r1zd 455 14 for for IN cord-015569-vy49r1zd 455 15 increasing increase VBG cord-015569-vy49r1zd 455 16 delicious delicious JJ cord-015569-vy49r1zd 455 17 feelings feeling NNS cord-015569-vy49r1zd 455 18 during during IN cord-015569-vy49r1zd 455 19 having have VBG cord-015569-vy49r1zd 455 20 sweet sweet JJ cord-015569-vy49r1zd 455 21 foods food NNS cord-015569-vy49r1zd 455 22 , , , cord-015569-vy49r1zd 455 23 in in IN cord-015569-vy49r1zd 455 24 which which WDT cord-015569-vy49r1zd 455 25 beta beta NN cord-015569-vy49r1zd 455 26 frequency frequency NN cord-015569-vy49r1zd 455 27 rhythms rhythm NNS cord-015569-vy49r1zd 455 28 may may MD cord-015569-vy49r1zd 455 29 be be VB cord-015569-vy49r1zd 455 30 concerned concern VBN cord-015569-vy49r1zd 455 31 with with IN cord-015569-vy49r1zd 455 32 producing produce VBG cord-015569-vy49r1zd 455 33 comprehensive comprehensive JJ cord-015569-vy49r1zd 455 34 feelings feeling NNS cord-015569-vy49r1zd 455 35 of of IN cord-015569-vy49r1zd 455 36 deliciousness deliciousness NN cord-015569-vy49r1zd 455 37 . . . cord-015569-vy49r1zd 456 1 Though though IN cord-015569-vy49r1zd 456 2 it -PRON- PRP cord-015569-vy49r1zd 456 3 has have VBZ cord-015569-vy49r1zd 456 4 been be VBN cord-015569-vy49r1zd 456 5 reported report VBN cord-015569-vy49r1zd 456 6 that that IN cord-015569-vy49r1zd 456 7 capsaicin capsaicin NN cord-015569-vy49r1zd 456 8 possesses possess VBZ cord-015569-vy49r1zd 456 9 effects effect NNS cord-015569-vy49r1zd 456 10 of of IN cord-015569-vy49r1zd 456 11 stomach stomach NN cord-015569-vy49r1zd 456 12 protection protection NN cord-015569-vy49r1zd 456 13 and and CC cord-015569-vy49r1zd 456 14 appetite appetite NN cord-015569-vy49r1zd 456 15 improvement improvement NN cord-015569-vy49r1zd 456 16 , , , cord-015569-vy49r1zd 456 17 the the DT cord-015569-vy49r1zd 456 18 influence influence NN cord-015569-vy49r1zd 456 19 of of IN cord-015569-vy49r1zd 456 20 dietary dietary JJ cord-015569-vy49r1zd 456 21 habits habit NNS cord-015569-vy49r1zd 456 22 of of IN cord-015569-vy49r1zd 456 23 consuming consume VBG cord-015569-vy49r1zd 456 24 pungent pungent JJ cord-015569-vy49r1zd 456 25 substance substance NN cord-015569-vy49r1zd 456 26 such such JJ cord-015569-vy49r1zd 456 27 as as IN cord-015569-vy49r1zd 456 28 capsaicin capsaicin NN cord-015569-vy49r1zd 456 29 on on IN cord-015569-vy49r1zd 456 30 taste taste NN cord-015569-vy49r1zd 456 31 sensitivity sensitivity NN cord-015569-vy49r1zd 456 32 has have VBZ cord-015569-vy49r1zd 456 33 not not RB cord-015569-vy49r1zd 456 34 been be VBN cord-015569-vy49r1zd 456 35 investigated investigate VBN cord-015569-vy49r1zd 456 36 . . . cord-015569-vy49r1zd 457 1 In in IN cord-015569-vy49r1zd 457 2 order order NN cord-015569-vy49r1zd 457 3 to to TO cord-015569-vy49r1zd 457 4 elucidate elucidate VB cord-015569-vy49r1zd 457 5 the the DT cord-015569-vy49r1zd 457 6 influence influence NN cord-015569-vy49r1zd 457 7 of of IN cord-015569-vy49r1zd 457 8 dietary dietary JJ cord-015569-vy49r1zd 457 9 intake intake NN cord-015569-vy49r1zd 457 10 of of IN cord-015569-vy49r1zd 457 11 capsaicin capsaicin NN cord-015569-vy49r1zd 457 12 on on IN cord-015569-vy49r1zd 457 13 taste taste NN cord-015569-vy49r1zd 457 14 and and CC cord-015569-vy49r1zd 457 15 pungent pungent JJ cord-015569-vy49r1zd 457 16 sensitivities sensitivity NNS cord-015569-vy49r1zd 457 17 , , , cord-015569-vy49r1zd 457 18 we -PRON- PRP cord-015569-vy49r1zd 457 19 measured measure VBD cord-015569-vy49r1zd 457 20 the the DT cord-015569-vy49r1zd 457 21 thresholds threshold NNS cord-015569-vy49r1zd 457 22 for for IN cord-015569-vy49r1zd 457 23 5 5 CD cord-015569-vy49r1zd 457 24 basic basic JJ cord-015569-vy49r1zd 457 25 tastes taste NNS cord-015569-vy49r1zd 457 26 and and CC cord-015569-vy49r1zd 457 27 capsaicin capsaicin NNS cord-015569-vy49r1zd 457 28 in in IN cord-015569-vy49r1zd 457 29 Thai Thai NNP cord-015569-vy49r1zd 457 30 and and CC cord-015569-vy49r1zd 457 31 Japanese Japanese NNP cord-015569-vy49r1zd 457 32 , , , cord-015569-vy49r1zd 457 33 because because IN cord-015569-vy49r1zd 457 34 Thai Thai NNP cord-015569-vy49r1zd 457 35 have have VBP cord-015569-vy49r1zd 457 36 a a DT cord-015569-vy49r1zd 457 37 dietary dietary JJ cord-015569-vy49r1zd 457 38 habit habit NN cord-015569-vy49r1zd 457 39 of of IN cord-015569-vy49r1zd 457 40 much much RB cord-015569-vy49r1zd 457 41 more more JJR cord-015569-vy49r1zd 457 42 use use NN cord-015569-vy49r1zd 457 43 of of IN cord-015569-vy49r1zd 457 44 pungent pungent JJ cord-015569-vy49r1zd 457 45 substances substance NNS cord-015569-vy49r1zd 457 46 for for IN cord-015569-vy49r1zd 457 47 meal meal NN cord-015569-vy49r1zd 457 48 than than IN cord-015569-vy49r1zd 457 49 Japanese Japanese NNP cord-015569-vy49r1zd 457 50 . . . cord-015569-vy49r1zd 458 1 In in IN cord-015569-vy49r1zd 458 2 addition addition NN cord-015569-vy49r1zd 458 3 , , , cord-015569-vy49r1zd 458 4 we -PRON- PRP cord-015569-vy49r1zd 458 5 conducted conduct VBD cord-015569-vy49r1zd 458 6 questionnaire questionnaire NN cord-015569-vy49r1zd 458 7 study study NN cord-015569-vy49r1zd 458 8 about about IN cord-015569-vy49r1zd 458 9 dietary dietary JJ cord-015569-vy49r1zd 458 10 habits habit NNS cord-015569-vy49r1zd 458 11 of of IN cord-015569-vy49r1zd 458 12 both both DT cord-015569-vy49r1zd 458 13 groups group NNS cord-015569-vy49r1zd 458 14 . . . cord-015569-vy49r1zd 459 1 Regarding regard VBG cord-015569-vy49r1zd 459 2 the the DT cord-015569-vy49r1zd 459 3 recognition recognition NN cord-015569-vy49r1zd 459 4 thresholds threshold NNS cord-015569-vy49r1zd 459 5 for for IN cord-015569-vy49r1zd 459 6 5 5 CD cord-015569-vy49r1zd 459 7 basic basic JJ cord-015569-vy49r1zd 459 8 tastes taste NNS cord-015569-vy49r1zd 459 9 , , , cord-015569-vy49r1zd 459 10 the the DT cord-015569-vy49r1zd 459 11 threshold threshold NN cord-015569-vy49r1zd 459 12 for for IN cord-015569-vy49r1zd 459 13 umami umami NN cord-015569-vy49r1zd 459 14 tended tend VBD cord-015569-vy49r1zd 459 15 to to TO cord-015569-vy49r1zd 459 16 be be VB cord-015569-vy49r1zd 459 17 higher high JJR cord-015569-vy49r1zd 459 18 in in IN cord-015569-vy49r1zd 459 19 Thai Thai NNP cord-015569-vy49r1zd 459 20 compared compare VBN cord-015569-vy49r1zd 459 21 to to IN cord-015569-vy49r1zd 459 22 Japanese Japanese NNP cord-015569-vy49r1zd 459 23 with with IN cord-015569-vy49r1zd 459 24 no no DT cord-015569-vy49r1zd 459 25 differences difference NNS cord-015569-vy49r1zd 459 26 in in IN cord-015569-vy49r1zd 459 27 other other JJ cord-015569-vy49r1zd 459 28 basic basic JJ cord-015569-vy49r1zd 459 29 tastes taste NNS cord-015569-vy49r1zd 459 30 . . . cord-015569-vy49r1zd 460 1 This this DT cord-015569-vy49r1zd 460 2 result result NN cord-015569-vy49r1zd 460 3 indicates indicate VBZ cord-015569-vy49r1zd 460 4 that that IN cord-015569-vy49r1zd 460 5 daily daily JJ cord-015569-vy49r1zd 460 6 high high JJ cord-015569-vy49r1zd 460 7 intake intake NN cord-015569-vy49r1zd 460 8 of of IN cord-015569-vy49r1zd 460 9 pungent pungent JJ cord-015569-vy49r1zd 460 10 substances substance NNS cord-015569-vy49r1zd 460 11 hardly hardly RB cord-015569-vy49r1zd 460 12 affect affect VBP cord-015569-vy49r1zd 460 13 taste taste NN cord-015569-vy49r1zd 460 14 sensitivities sensitivity NNS cord-015569-vy49r1zd 460 15 . . . cord-015569-vy49r1zd 461 1 However however RB cord-015569-vy49r1zd 461 2 , , , cord-015569-vy49r1zd 461 3 the the DT cord-015569-vy49r1zd 461 4 threshold threshold NN cord-015569-vy49r1zd 461 5 for for IN cord-015569-vy49r1zd 461 6 capsaicin capsaicin NN cord-015569-vy49r1zd 461 7 in in IN cord-015569-vy49r1zd 461 8 Thai Thai NNP cord-015569-vy49r1zd 461 9 was be VBD cord-015569-vy49r1zd 461 10 significantly significantly RB cord-015569-vy49r1zd 461 11 higher high JJR cord-015569-vy49r1zd 461 12 than than IN cord-015569-vy49r1zd 461 13 Japanese Japanese NNP cord-015569-vy49r1zd 461 14 , , , cord-015569-vy49r1zd 461 15 which which WDT cord-015569-vy49r1zd 461 16 was be VBD cord-015569-vy49r1zd 461 17 considered consider VBN cord-015569-vy49r1zd 461 18 to to TO cord-015569-vy49r1zd 461 19 result result VB cord-015569-vy49r1zd 461 20 from from IN cord-015569-vy49r1zd 461 21 much much RB cord-015569-vy49r1zd 461 22 more more JJR cord-015569-vy49r1zd 461 23 use use NN cord-015569-vy49r1zd 461 24 of of IN cord-015569-vy49r1zd 461 25 hot hot JJ cord-015569-vy49r1zd 461 26 pepper pepper NN cord-015569-vy49r1zd 461 27 for for IN cord-015569-vy49r1zd 461 28 meal meal NN cord-015569-vy49r1zd 461 29 in in IN cord-015569-vy49r1zd 461 30 Thai Thai NNP cord-015569-vy49r1zd 461 31 . . . cord-015569-vy49r1zd 462 1 When when WRB cord-015569-vy49r1zd 462 2 the the DT cord-015569-vy49r1zd 462 3 thresholds threshold NNS cord-015569-vy49r1zd 462 4 for for IN cord-015569-vy49r1zd 462 5 5 5 CD cord-015569-vy49r1zd 462 6 basic basic JJ cord-015569-vy49r1zd 462 7 tastes taste NNS cord-015569-vy49r1zd 462 8 were be VBD cord-015569-vy49r1zd 462 9 measured measure VBN cord-015569-vy49r1zd 462 10 immediately immediately RB cord-015569-vy49r1zd 462 11 after after IN cord-015569-vy49r1zd 462 12 capsaicin capsaicin NN cord-015569-vy49r1zd 462 13 stimulation stimulation NN cord-015569-vy49r1zd 462 14 , , , cord-015569-vy49r1zd 462 15 the the DT cord-015569-vy49r1zd 462 16 thresholds threshold NNS cord-015569-vy49r1zd 462 17 for for IN cord-015569-vy49r1zd 462 18 acid acid NN cord-015569-vy49r1zd 462 19 and and CC cord-015569-vy49r1zd 462 20 bitter bitter JJ cord-015569-vy49r1zd 462 21 tastes taste NNS cord-015569-vy49r1zd 462 22 were be VBD cord-015569-vy49r1zd 462 23 elevated elevate VBN cord-015569-vy49r1zd 462 24 in in IN cord-015569-vy49r1zd 462 25 Thai Thai NNP cord-015569-vy49r1zd 462 26 whereas whereas IN cord-015569-vy49r1zd 462 27 they -PRON- PRP cord-015569-vy49r1zd 462 28 did do VBD cord-015569-vy49r1zd 462 29 not not RB cord-015569-vy49r1zd 462 30 change change VB cord-015569-vy49r1zd 462 31 in in IN cord-015569-vy49r1zd 462 32 Japanese Japanese NNP cord-015569-vy49r1zd 462 33 . . . cord-015569-vy49r1zd 463 1 This this DT cord-015569-vy49r1zd 463 2 difference difference NN cord-015569-vy49r1zd 463 3 may may MD cord-015569-vy49r1zd 463 4 be be VB cord-015569-vy49r1zd 463 5 due due JJ cord-015569-vy49r1zd 463 6 to to IN cord-015569-vy49r1zd 463 7 the the DT cord-015569-vy49r1zd 463 8 concentration concentration NN cord-015569-vy49r1zd 463 9 of of IN cord-015569-vy49r1zd 463 10 pretreatment pretreatment NN cord-015569-vy49r1zd 463 11 capsaicin capsaicin NNS cord-015569-vy49r1zd 463 12 because because IN cord-015569-vy49r1zd 463 13 suprathreshold suprathreshold JJ cord-015569-vy49r1zd 463 14 concentration concentration NN cord-015569-vy49r1zd 463 15 was be VBD cord-015569-vy49r1zd 463 16 used use VBN cord-015569-vy49r1zd 463 17 in in IN cord-015569-vy49r1zd 463 18 the the DT cord-015569-vy49r1zd 463 19 experiment experiment NN cord-015569-vy49r1zd 463 20 , , , cord-015569-vy49r1zd 463 21 showing show VBG cord-015569-vy49r1zd 463 22 that that IN cord-015569-vy49r1zd 463 23 high high JJ cord-015569-vy49r1zd 463 24 concentration concentration NN cord-015569-vy49r1zd 463 25 of of IN cord-015569-vy49r1zd 463 26 capsaicin capsaicin NN cord-015569-vy49r1zd 463 27 may may MD cord-015569-vy49r1zd 463 28 cause cause VB cord-015569-vy49r1zd 463 29 transient transient JJ cord-015569-vy49r1zd 463 30 impairment impairment NN cord-015569-vy49r1zd 463 31 in in IN cord-015569-vy49r1zd 463 32 some some DT cord-015569-vy49r1zd 463 33 taste taste NN cord-015569-vy49r1zd 463 34 sensitivities sensitivity NNS cord-015569-vy49r1zd 463 35 . . . cord-015569-vy49r1zd 464 1 In in IN cord-015569-vy49r1zd 464 2 conclusion conclusion NN cord-015569-vy49r1zd 464 3 , , , cord-015569-vy49r1zd 464 4 it -PRON- PRP cord-015569-vy49r1zd 464 5 was be VBD cord-015569-vy49r1zd 464 6 suggested suggest VBN cord-015569-vy49r1zd 464 7 that that IN cord-015569-vy49r1zd 464 8 daily daily JJ cord-015569-vy49r1zd 464 9 high high JJ cord-015569-vy49r1zd 464 10 consumption consumption NN cord-015569-vy49r1zd 464 11 of of IN cord-015569-vy49r1zd 464 12 pungent pungent JJ cord-015569-vy49r1zd 464 13 substances substance NNS cord-015569-vy49r1zd 464 14 hardly hardly RB cord-015569-vy49r1zd 464 15 affects affect VBZ cord-015569-vy49r1zd 464 16 taste taste NN cord-015569-vy49r1zd 464 17 sensitivities sensitivity NNS cord-015569-vy49r1zd 464 18 but but CC cord-015569-vy49r1zd 464 19 high high JJ cord-015569-vy49r1zd 464 20 concentration concentration NN cord-015569-vy49r1zd 464 21 of of IN cord-015569-vy49r1zd 464 22 capsaicin capsaicin NN cord-015569-vy49r1zd 464 23 causes cause VBZ cord-015569-vy49r1zd 464 24 transient transient JJ cord-015569-vy49r1zd 464 25 hyposensitivity hyposensitivity NN cord-015569-vy49r1zd 464 26 of of IN cord-015569-vy49r1zd 464 27 some some DT cord-015569-vy49r1zd 464 28 tastes taste NNS cord-015569-vy49r1zd 464 29 . . . cord-015569-vy49r1zd 465 1 This this DT cord-015569-vy49r1zd 465 2 study study NN cord-015569-vy49r1zd 465 3 aimed aim VBD cord-015569-vy49r1zd 465 4 to to TO cord-015569-vy49r1zd 465 5 investigate investigate VB cord-015569-vy49r1zd 465 6 what what WP cord-015569-vy49r1zd 465 7 flavors flavor NNS cord-015569-vy49r1zd 465 8 show show VBP cord-015569-vy49r1zd 465 9 interaction interaction NN cord-015569-vy49r1zd 465 10 with with IN cord-015569-vy49r1zd 465 11 Umami Umami NNP cord-015569-vy49r1zd 465 12 taste taste NN cord-015569-vy49r1zd 465 13 . . . cord-015569-vy49r1zd 466 1 Twenty twenty CD cord-015569-vy49r1zd 466 2 - - HYPH cord-015569-vy49r1zd 466 3 one one CD cord-015569-vy49r1zd 466 4 female female JJ cord-015569-vy49r1zd 466 5 university university NN cord-015569-vy49r1zd 466 6 students student NNS cord-015569-vy49r1zd 466 7 participated participate VBD cord-015569-vy49r1zd 466 8 in in IN cord-015569-vy49r1zd 466 9 this this DT cord-015569-vy49r1zd 466 10 study study NN cord-015569-vy49r1zd 466 11 . . . cord-015569-vy49r1zd 467 1 Solutions solution NNS cord-015569-vy49r1zd 467 2 of of IN cord-015569-vy49r1zd 467 3 0.25 0.25 CD cord-015569-vy49r1zd 467 4 % % NN cord-015569-vy49r1zd 467 5 MSG MSG NNP cord-015569-vy49r1zd 467 6 were be VBD cord-015569-vy49r1zd 467 7 used use VBN cord-015569-vy49r1zd 467 8 as as IN cord-015569-vy49r1zd 467 9 taste taste NN cord-015569-vy49r1zd 467 10 stimuli stimulus NNS cord-015569-vy49r1zd 467 11 , , , cord-015569-vy49r1zd 467 12 and and CC cord-015569-vy49r1zd 467 13 the the DT cord-015569-vy49r1zd 467 14 19 19 CD cord-015569-vy49r1zd 467 15 kinds kind NNS cord-015569-vy49r1zd 467 16 of of IN cord-015569-vy49r1zd 467 17 flavors flavor NNS cord-015569-vy49r1zd 467 18 were be VBD cord-015569-vy49r1zd 467 19 used use VBN cord-015569-vy49r1zd 467 20 as as IN cord-015569-vy49r1zd 467 21 flavor flavor NN cord-015569-vy49r1zd 467 22 stimuli stimulus NNS cord-015569-vy49r1zd 467 23 . . . cord-015569-vy49r1zd 468 1 Participants participant NNS cord-015569-vy49r1zd 468 2 were be VBD cord-015569-vy49r1zd 468 3 asked ask VBN cord-015569-vy49r1zd 468 4 to to TO cord-015569-vy49r1zd 468 5 taste taste VB cord-015569-vy49r1zd 468 6 a a DT cord-015569-vy49r1zd 468 7 pair pair NN cord-015569-vy49r1zd 468 8 of of IN cord-015569-vy49r1zd 468 9 flavor flavor NN cord-015569-vy49r1zd 468 10 and and CC cord-015569-vy49r1zd 468 11 MSG MSG NNP cord-015569-vy49r1zd 468 12 solution solution NN cord-015569-vy49r1zd 468 13 , , , cord-015569-vy49r1zd 468 14 and and CC cord-015569-vy49r1zd 468 15 to to TO cord-015569-vy49r1zd 468 16 evaluate evaluate VB cord-015569-vy49r1zd 468 17 the the DT cord-015569-vy49r1zd 468 18 intensity intensity NN cord-015569-vy49r1zd 468 19 of of IN cord-015569-vy49r1zd 468 20 umami umami NN cord-015569-vy49r1zd 468 21 taste taste NN cord-015569-vy49r1zd 468 22 and and CC cord-015569-vy49r1zd 468 23 the the DT cord-015569-vy49r1zd 468 24 congruency congruency NN cord-015569-vy49r1zd 468 25 of of IN cord-015569-vy49r1zd 468 26 the the DT cord-015569-vy49r1zd 468 27 flavor flavor NN cord-015569-vy49r1zd 468 28 with with IN cord-015569-vy49r1zd 468 29 the the DT cord-015569-vy49r1zd 468 30 umami umami NN cord-015569-vy49r1zd 468 31 . . . cord-015569-vy49r1zd 469 1 When when WRB cord-015569-vy49r1zd 469 2 the the DT cord-015569-vy49r1zd 469 3 participants participant NNS cord-015569-vy49r1zd 469 4 taste taste VBP cord-015569-vy49r1zd 469 5 MSG MSG NNP cord-015569-vy49r1zd 469 6 solution solution NN cord-015569-vy49r1zd 469 7 with with IN cord-015569-vy49r1zd 469 8 flavor flavor NN cord-015569-vy49r1zd 469 9 of of IN cord-015569-vy49r1zd 469 10 dried dry VBN cord-015569-vy49r1zd 469 11 bonito bonito NNP cord-015569-vy49r1zd 469 12 , , , cord-015569-vy49r1zd 469 13 and and CC cord-015569-vy49r1zd 469 14 of of IN cord-015569-vy49r1zd 469 15 garlic garlic NN cord-015569-vy49r1zd 469 16 , , , cord-015569-vy49r1zd 469 17 they -PRON- PRP cord-015569-vy49r1zd 469 18 evaluated evaluate VBD cord-015569-vy49r1zd 469 19 the the DT cord-015569-vy49r1zd 469 20 umami umami NN cord-015569-vy49r1zd 469 21 taste taste NN cord-015569-vy49r1zd 469 22 stronger strong JJR cord-015569-vy49r1zd 469 23 than than IN cord-015569-vy49r1zd 469 24 when when WRB cord-015569-vy49r1zd 469 25 they -PRON- PRP cord-015569-vy49r1zd 469 26 taste taste VBP cord-015569-vy49r1zd 469 27 it -PRON- PRP cord-015569-vy49r1zd 469 28 without without IN cord-015569-vy49r1zd 469 29 flavors flavor NNS cord-015569-vy49r1zd 469 30 ( ( -LRB- cord-015569-vy49r1zd 469 31 potentiation potentiation NN cord-015569-vy49r1zd 469 32 effect effect NN cord-015569-vy49r1zd 469 33 ) ) -RRB- cord-015569-vy49r1zd 469 34 . . . cord-015569-vy49r1zd 470 1 When when WRB cord-015569-vy49r1zd 470 2 the the DT cord-015569-vy49r1zd 470 3 participants participant NNS cord-015569-vy49r1zd 470 4 taste taste VBP cord-015569-vy49r1zd 470 5 MSG MSG NNP cord-015569-vy49r1zd 470 6 solution solution NN cord-015569-vy49r1zd 470 7 with with IN cord-015569-vy49r1zd 470 8 flavor flavor NN cord-015569-vy49r1zd 470 9 of of IN cord-015569-vy49r1zd 470 10 tomato tomato NN cord-015569-vy49r1zd 470 11 , , , cord-015569-vy49r1zd 470 12 of of IN cord-015569-vy49r1zd 470 13 garlic garlic NN cord-015569-vy49r1zd 470 14 , , , cord-015569-vy49r1zd 470 15 and and CC cord-015569-vy49r1zd 470 16 of of IN cord-015569-vy49r1zd 470 17 onion onion NN cord-015569-vy49r1zd 470 18 , , , cord-015569-vy49r1zd 470 19 they -PRON- PRP cord-015569-vy49r1zd 470 20 evaluated evaluate VBD cord-015569-vy49r1zd 470 21 those those DT cord-015569-vy49r1zd 470 22 flavors flavor NNS cord-015569-vy49r1zd 470 23 more more RBR cord-015569-vy49r1zd 470 24 congruent congruent JJ cord-015569-vy49r1zd 470 25 with with IN cord-015569-vy49r1zd 470 26 umami umami JJ cord-015569-vy49r1zd 470 27 taste taste NN cord-015569-vy49r1zd 470 28 than than IN cord-015569-vy49r1zd 470 29 when when WRB cord-015569-vy49r1zd 470 30 they -PRON- PRP cord-015569-vy49r1zd 470 31 taste taste VBP cord-015569-vy49r1zd 470 32 it -PRON- PRP cord-015569-vy49r1zd 470 33 without without IN cord-015569-vy49r1zd 470 34 flavors flavor NNS cord-015569-vy49r1zd 470 35 . . . cord-015569-vy49r1zd 471 1 They -PRON- PRP cord-015569-vy49r1zd 471 2 evaluated evaluate VBD cord-015569-vy49r1zd 471 3 congruency congruency NN cord-015569-vy49r1zd 471 4 of of IN cord-015569-vy49r1zd 471 5 dried dry VBN cord-015569-vy49r1zd 471 6 bonito bonito NNP cord-015569-vy49r1zd 471 7 and and CC cord-015569-vy49r1zd 471 8 of of IN cord-015569-vy49r1zd 471 9 matsutake matsutake NN cord-015569-vy49r1zd 471 10 less less RBR cord-015569-vy49r1zd 471 11 congruent congruent JJ cord-015569-vy49r1zd 471 12 with with IN cord-015569-vy49r1zd 471 13 umami umami JJ cord-015569-vy49r1zd 471 14 taste taste NN cord-015569-vy49r1zd 471 15 . . . cord-015569-vy49r1zd 472 1 There there EX cord-015569-vy49r1zd 472 2 is be VBZ cord-015569-vy49r1zd 472 3 a a DT cord-015569-vy49r1zd 472 4 significant significant JJ cord-015569-vy49r1zd 472 5 , , , cord-015569-vy49r1zd 472 6 but but CC cord-015569-vy49r1zd 472 7 weak weak JJ cord-015569-vy49r1zd 472 8 , , , cord-015569-vy49r1zd 472 9 interaction interaction NN cord-015569-vy49r1zd 472 10 between between IN cord-015569-vy49r1zd 472 11 the the DT cord-015569-vy49r1zd 472 12 congruency congruency NN cord-015569-vy49r1zd 472 13 with with IN cord-015569-vy49r1zd 472 14 umami umami NN cord-015569-vy49r1zd 472 15 taste taste NN cord-015569-vy49r1zd 472 16 and and CC cord-015569-vy49r1zd 472 17 the the DT cord-015569-vy49r1zd 472 18 potentiation potentiation NN cord-015569-vy49r1zd 472 19 effect effect NN cord-015569-vy49r1zd 472 20 of of IN cord-015569-vy49r1zd 472 21 umami umami NN cord-015569-vy49r1zd 472 22 taste taste NN cord-015569-vy49r1zd 472 23 ( ( -LRB- cord-015569-vy49r1zd 472 24 r=0.36 r=0.36 NN cord-015569-vy49r1zd 472 25 , , , cord-015569-vy49r1zd 472 26 p<0.05 p<0.05 CD cord-015569-vy49r1zd 472 27 ) ) -RRB- cord-015569-vy49r1zd 472 28 . . . cord-015569-vy49r1zd 473 1 In in IN cord-015569-vy49r1zd 473 2 general general JJ cord-015569-vy49r1zd 473 3 , , , cord-015569-vy49r1zd 473 4 the the DT cord-015569-vy49r1zd 473 5 flavors flavor NNS cord-015569-vy49r1zd 473 6 that that WDT cord-015569-vy49r1zd 473 7 are be VBP cord-015569-vy49r1zd 473 8 experienced experience VBN cord-015569-vy49r1zd 473 9 in in IN cord-015569-vy49r1zd 473 10 our -PRON- PRP$ cord-015569-vy49r1zd 473 11 daily daily JJ cord-015569-vy49r1zd 473 12 lives life NNS cord-015569-vy49r1zd 473 13 are be VBP cord-015569-vy49r1zd 473 14 evaluated evaluate VBN cord-015569-vy49r1zd 473 15 more more RBR cord-015569-vy49r1zd 473 16 congruent congruent JJ cord-015569-vy49r1zd 473 17 with with IN cord-015569-vy49r1zd 473 18 umami umami JJ cord-015569-vy49r1zd 473 19 taste taste NN cord-015569-vy49r1zd 473 20 , , , cord-015569-vy49r1zd 473 21 and and CC cord-015569-vy49r1zd 473 22 have have VBP cord-015569-vy49r1zd 473 23 potentiation potentiation NN cord-015569-vy49r1zd 473 24 effect effect NN cord-015569-vy49r1zd 473 25 on on IN cord-015569-vy49r1zd 473 26 umami umami JJ cord-015569-vy49r1zd 473 27 taste taste NN cord-015569-vy49r1zd 473 28 perception perception NN cord-015569-vy49r1zd 473 29 . . . cord-015569-vy49r1zd 474 1 Preceding precede VBG cord-015569-vy49r1zd 474 2 studies study NNS cord-015569-vy49r1zd 474 3 also also RB cord-015569-vy49r1zd 474 4 suggest suggest VBP cord-015569-vy49r1zd 474 5 that that IN cord-015569-vy49r1zd 474 6 the the DT cord-015569-vy49r1zd 474 7 interaction interaction NN cord-015569-vy49r1zd 474 8 between between IN cord-015569-vy49r1zd 474 9 olfaction olfaction NN cord-015569-vy49r1zd 474 10 and and CC cord-015569-vy49r1zd 474 11 taste taste NN cord-015569-vy49r1zd 474 12 , , , cord-015569-vy49r1zd 474 13 and and CC cord-015569-vy49r1zd 474 14 perception perception NN cord-015569-vy49r1zd 474 15 of of IN cord-015569-vy49r1zd 474 16 umami umami NN cord-015569-vy49r1zd 474 17 taste taste NN cord-015569-vy49r1zd 474 18 are be VBP cord-015569-vy49r1zd 474 19 based base VBN cord-015569-vy49r1zd 474 20 on on IN cord-015569-vy49r1zd 474 21 learning learn VBG cord-015569-vy49r1zd 474 22 . . . cord-015569-vy49r1zd 475 1 This this DT cord-015569-vy49r1zd 475 2 study study NN cord-015569-vy49r1zd 475 3 also also RB cord-015569-vy49r1zd 475 4 supports support VBZ cord-015569-vy49r1zd 475 5 the the DT cord-015569-vy49r1zd 475 6 view view NN cord-015569-vy49r1zd 475 7 of of IN cord-015569-vy49r1zd 475 8 ' ' '' cord-015569-vy49r1zd 475 9 ' ' '' cord-015569-vy49r1zd 475 10 learned learn VBD cord-015569-vy49r1zd 475 11 synesthesia synesthesia NN cord-015569-vy49r1zd 475 12 ' ' '' cord-015569-vy49r1zd 475 13 ' ' '' cord-015569-vy49r1zd 475 14 of of IN cord-015569-vy49r1zd 475 15 olfaction olfaction NN cord-015569-vy49r1zd 475 16 and and CC cord-015569-vy49r1zd 475 17 taste taste NN cord-015569-vy49r1zd 475 18 . . . cord-015569-vy49r1zd 476 1 Acknowledgment acknowledgment NN cord-015569-vy49r1zd 476 2 : : : cord-015569-vy49r1zd 477 1 This this DT cord-015569-vy49r1zd 477 2 study study NN cord-015569-vy49r1zd 477 3 was be VBD cord-015569-vy49r1zd 477 4 supported support VBN cord-015569-vy49r1zd 477 5 by by IN cord-015569-vy49r1zd 477 6 Society Society NNP cord-015569-vy49r1zd 477 7 for for IN cord-015569-vy49r1zd 477 8 Research Research NNP cord-015569-vy49r1zd 477 9 on on IN cord-015569-vy49r1zd 477 10 Umami Umami NNP cord-015569-vy49r1zd 477 11 Taste Taste NNP cord-015569-vy49r1zd 477 12 . . . cord-015569-vy49r1zd 478 1 Eating eat VBG cord-015569-vy49r1zd 478 2 with with IN cord-015569-vy49r1zd 478 3 someone someone NN cord-015569-vy49r1zd 478 4 makes make VBZ cord-015569-vy49r1zd 478 5 the the DT cord-015569-vy49r1zd 478 6 foods food NNS cord-015569-vy49r1zd 478 7 more more RBR cord-015569-vy49r1zd 478 8 palatable palatable JJ cord-015569-vy49r1zd 478 9 , , , cord-015569-vy49r1zd 478 10 and and CC cord-015569-vy49r1zd 478 11 the the DT cord-015569-vy49r1zd 478 12 family family NN cord-015569-vy49r1zd 478 13 ties tie VBZ cord-015569-vy49r1zd 478 14 more more RBR cord-015569-vy49r1zd 478 15 strong strong JJ cord-015569-vy49r1zd 478 16 . . . cord-015569-vy49r1zd 479 1 On on IN cord-015569-vy49r1zd 479 2 the the DT cord-015569-vy49r1zd 479 3 other other JJ cord-015569-vy49r1zd 479 4 hands hand NNS cord-015569-vy49r1zd 479 5 , , , cord-015569-vy49r1zd 479 6 eating eat VBG cord-015569-vy49r1zd 479 7 alone alone JJ cord-015569-vy49r1zd 479 8 ( ( -LRB- cord-015569-vy49r1zd 479 9 KO KO NNP cord-015569-vy49r1zd 479 10 - - HYPH cord-015569-vy49r1zd 479 11 SHO SHO NNP cord-015569-vy49r1zd 479 12 - - HYPH cord-015569-vy49r1zd 479 13 KU KU NNP cord-015569-vy49r1zd 479 14 , , , cord-015569-vy49r1zd 479 15 in in IN cord-015569-vy49r1zd 479 16 Japanese Japanese NNP cord-015569-vy49r1zd 479 17 ) ) -RRB- cord-015569-vy49r1zd 479 18 has have VBZ cord-015569-vy49r1zd 479 19 many many JJ cord-015569-vy49r1zd 479 20 problems problem NNS cord-015569-vy49r1zd 479 21 , , , cord-015569-vy49r1zd 479 22 such such JJ cord-015569-vy49r1zd 479 23 as as IN cord-015569-vy49r1zd 479 24 malnutrition malnutrition NN cord-015569-vy49r1zd 479 25 , , , cord-015569-vy49r1zd 479 26 unbalanced unbalanced JJ cord-015569-vy49r1zd 479 27 meals meal NNS cord-015569-vy49r1zd 479 28 , , , cord-015569-vy49r1zd 479 29 not not RB cord-015569-vy49r1zd 479 30 good good JJ cord-015569-vy49r1zd 479 31 at at IN cord-015569-vy49r1zd 479 32 communication communication NN cord-015569-vy49r1zd 479 33 etc etc FW cord-015569-vy49r1zd 479 34 . . . cord-015569-vy49r1zd 480 1 KO KO NNP cord-015569-vy49r1zd 480 2 - - HYPH cord-015569-vy49r1zd 480 3 SHO SHO NNP cord-015569-vy49r1zd 480 4 - - HYPH cord-015569-vy49r1zd 480 5 KU KU NNP cord-015569-vy49r1zd 480 6 is be VBZ cord-015569-vy49r1zd 480 7 very very RB cord-015569-vy49r1zd 480 8 severe severe JJ cord-015569-vy49r1zd 480 9 problems problem NNS cord-015569-vy49r1zd 480 10 in in IN cord-015569-vy49r1zd 480 11 modern modern JJ cord-015569-vy49r1zd 480 12 Japanese japanese JJ cord-015569-vy49r1zd 480 13 society society NN cord-015569-vy49r1zd 480 14 . . . cord-015569-vy49r1zd 481 1 Thus thus RB cord-015569-vy49r1zd 481 2 , , , cord-015569-vy49r1zd 481 3 we -PRON- PRP cord-015569-vy49r1zd 481 4 aimed aim VBD cord-015569-vy49r1zd 481 5 to to TO cord-015569-vy49r1zd 481 6 study study VB cord-015569-vy49r1zd 481 7 the the DT cord-015569-vy49r1zd 481 8 effect effect NN cord-015569-vy49r1zd 481 9 of of IN cord-015569-vy49r1zd 481 10 KO KO NNP cord-015569-vy49r1zd 481 11 - - HYPH cord-015569-vy49r1zd 481 12 SHO SHO NNP cord-015569-vy49r1zd 481 13 - - HYPH cord-015569-vy49r1zd 481 14 KU KU NNP cord-015569-vy49r1zd 481 15 on on IN cord-015569-vy49r1zd 481 16 palatability palatability NN cord-015569-vy49r1zd 481 17 of of IN cord-015569-vy49r1zd 481 18 the the DT cord-015569-vy49r1zd 481 19 foods food NNS cord-015569-vy49r1zd 481 20 . . . cord-015569-vy49r1zd 482 1 In in IN cord-015569-vy49r1zd 482 2 the the DT cord-015569-vy49r1zd 482 3 study study NN cord-015569-vy49r1zd 482 4 1 1 CD cord-015569-vy49r1zd 482 5 , , , cord-015569-vy49r1zd 482 6 ratings rating NNS cord-015569-vy49r1zd 482 7 for for IN cord-015569-vy49r1zd 482 8 taste taste NN cord-015569-vy49r1zd 482 9 and and CC cord-015569-vy49r1zd 482 10 palatability palatability NN cord-015569-vy49r1zd 482 11 of of IN cord-015569-vy49r1zd 482 12 confectioneries confectionery NNS cord-015569-vy49r1zd 482 13 were be VBD cord-015569-vy49r1zd 482 14 compared compare VBN cord-015569-vy49r1zd 482 15 between between IN cord-015569-vy49r1zd 482 16 when when WRB cord-015569-vy49r1zd 482 17 they -PRON- PRP cord-015569-vy49r1zd 482 18 were be VBD cord-015569-vy49r1zd 482 19 eaten eat VBN cord-015569-vy49r1zd 482 20 with with IN cord-015569-vy49r1zd 482 21 friends friend NNS cord-015569-vy49r1zd 482 22 and/or and/or CC cord-015569-vy49r1zd 482 23 family family NN cord-015569-vy49r1zd 482 24 members member NNS cord-015569-vy49r1zd 482 25 and and CC cord-015569-vy49r1zd 482 26 when when WRB cord-015569-vy49r1zd 482 27 eaten eat VBN cord-015569-vy49r1zd 482 28 alone alone RB cord-015569-vy49r1zd 482 29 . . . cord-015569-vy49r1zd 483 1 Thirty thirty CD cord-015569-vy49r1zd 483 2 six six CD cord-015569-vy49r1zd 483 3 female female JJ cord-015569-vy49r1zd 483 4 university university NN cord-015569-vy49r1zd 483 5 students student NNS cord-015569-vy49r1zd 483 6 participated participate VBD cord-015569-vy49r1zd 483 7 in in IN cord-015569-vy49r1zd 483 8 this this DT cord-015569-vy49r1zd 483 9 study study NN cord-015569-vy49r1zd 483 10 , , , cord-015569-vy49r1zd 483 11 and and CC cord-015569-vy49r1zd 483 12 were be VBD cord-015569-vy49r1zd 483 13 asked ask VBN cord-015569-vy49r1zd 483 14 to to TO cord-015569-vy49r1zd 483 15 eat eat VB cord-015569-vy49r1zd 483 16 two two CD cord-015569-vy49r1zd 483 17 kinds kind NNS cord-015569-vy49r1zd 483 18 of of IN cord-015569-vy49r1zd 483 19 chocolate chocolate NN cord-015569-vy49r1zd 483 20 and and CC cord-015569-vy49r1zd 483 21 two two CD cord-015569-vy49r1zd 483 22 kinds kind NNS cord-015569-vy49r1zd 483 23 of of IN cord-015569-vy49r1zd 483 24 cookies cookie NNS cord-015569-vy49r1zd 483 25 in in IN cord-015569-vy49r1zd 483 26 a a DT cord-015569-vy49r1zd 483 27 laboratory laboratory NN cord-015569-vy49r1zd 483 28 ( ( -LRB- cord-015569-vy49r1zd 483 29 alone alone RB cord-015569-vy49r1zd 483 30 ) ) -RRB- cord-015569-vy49r1zd 483 31 and and CC cord-015569-vy49r1zd 483 32 in in IN cord-015569-vy49r1zd 483 33 their -PRON- PRP$ cord-015569-vy49r1zd 483 34 home home NN cord-015569-vy49r1zd 483 35 ( ( -LRB- cord-015569-vy49r1zd 483 36 with with IN cord-015569-vy49r1zd 483 37 someone someone NN cord-015569-vy49r1zd 483 38 ) ) -RRB- cord-015569-vy49r1zd 483 39 . . . cord-015569-vy49r1zd 484 1 Palatability palatability NN cord-015569-vy49r1zd 484 2 ratings rating NNS cord-015569-vy49r1zd 484 3 were be VBD cord-015569-vy49r1zd 484 4 higher high JJR cord-015569-vy49r1zd 484 5 when when WRB cord-015569-vy49r1zd 484 6 they -PRON- PRP cord-015569-vy49r1zd 484 7 were be VBD cord-015569-vy49r1zd 484 8 eaten eat VBN cord-015569-vy49r1zd 484 9 with with IN cord-015569-vy49r1zd 484 10 someone someone NN cord-015569-vy49r1zd 484 11 in in IN cord-015569-vy49r1zd 484 12 their -PRON- PRP$ cord-015569-vy49r1zd 484 13 home home NN cord-015569-vy49r1zd 484 14 . . . cord-015569-vy49r1zd 485 1 In in IN cord-015569-vy49r1zd 485 2 the the DT cord-015569-vy49r1zd 485 3 study study NN cord-015569-vy49r1zd 485 4 2 2 CD cord-015569-vy49r1zd 485 5 , , , cord-015569-vy49r1zd 485 6 ratings rating NNS cord-015569-vy49r1zd 485 7 for for IN cord-015569-vy49r1zd 485 8 taste taste NN cord-015569-vy49r1zd 485 9 and and CC cord-015569-vy49r1zd 485 10 palatability palatability NN cord-015569-vy49r1zd 485 11 of of IN cord-015569-vy49r1zd 485 12 jellies jelly NNS cord-015569-vy49r1zd 485 13 were be VBD cord-015569-vy49r1zd 485 14 compared compare VBN cord-015569-vy49r1zd 485 15 between between IN cord-015569-vy49r1zd 485 16 when when WRB cord-015569-vy49r1zd 485 17 they -PRON- PRP cord-015569-vy49r1zd 485 18 were be VBD cord-015569-vy49r1zd 485 19 eaten eat VBN cord-015569-vy49r1zd 485 20 with with IN cord-015569-vy49r1zd 485 21 watching watch VBG cord-015569-vy49r1zd 485 22 a a DT cord-015569-vy49r1zd 485 23 child child NN cord-015569-vy49r1zd 485 24 eating eat VBG cord-015569-vy49r1zd 485 25 same same JJ cord-015569-vy49r1zd 485 26 jellies jelly NNS cord-015569-vy49r1zd 485 27 in in IN cord-015569-vy49r1zd 485 28 a a DT cord-015569-vy49r1zd 485 29 video video NN cord-015569-vy49r1zd 485 30 and and CC cord-015569-vy49r1zd 485 31 without without IN cord-015569-vy49r1zd 485 32 watching watch VBG cord-015569-vy49r1zd 485 33 it -PRON- PRP cord-015569-vy49r1zd 485 34 . . . cord-015569-vy49r1zd 486 1 Fifteen fifteen CD cord-015569-vy49r1zd 486 2 female female JJ cord-015569-vy49r1zd 486 3 university university NN cord-015569-vy49r1zd 486 4 students student NNS cord-015569-vy49r1zd 486 5 participated participate VBD cord-015569-vy49r1zd 486 6 in in IN cord-015569-vy49r1zd 486 7 this this DT cord-015569-vy49r1zd 486 8 study study NN cord-015569-vy49r1zd 486 9 , , , cord-015569-vy49r1zd 486 10 and and CC cord-015569-vy49r1zd 486 11 were be VBD cord-015569-vy49r1zd 486 12 asked ask VBN cord-015569-vy49r1zd 486 13 to to TO cord-015569-vy49r1zd 486 14 eat eat VB cord-015569-vy49r1zd 486 15 three three CD cord-015569-vy49r1zd 486 16 kinds kind NNS cord-015569-vy49r1zd 486 17 of of IN cord-015569-vy49r1zd 486 18 jellies jelly NNS cord-015569-vy49r1zd 486 19 in in IN cord-015569-vy49r1zd 486 20 a a DT cord-015569-vy49r1zd 486 21 laboratory laboratory NN cord-015569-vy49r1zd 486 22 and and CC cord-015569-vy49r1zd 486 23 to to TO cord-015569-vy49r1zd 486 24 rate rate VB cord-015569-vy49r1zd 486 25 a a DT cord-015569-vy49r1zd 486 26 questionnaire questionnaire NN cord-015569-vy49r1zd 486 27 about about IN cord-015569-vy49r1zd 486 28 their -PRON- PRP$ cord-015569-vy49r1zd 486 29 ability ability NN cord-015569-vy49r1zd 486 30 of of IN cord-015569-vy49r1zd 486 31 sympathy sympathy NN cord-015569-vy49r1zd 486 32 . . . cord-015569-vy49r1zd 487 1 Students student NNS cord-015569-vy49r1zd 487 2 with with IN cord-015569-vy49r1zd 487 3 high high JJ cord-015569-vy49r1zd 487 4 sympathy sympathy NN cord-015569-vy49r1zd 487 5 tend tend VBP cord-015569-vy49r1zd 487 6 to to TO cord-015569-vy49r1zd 487 7 rate rate VB cord-015569-vy49r1zd 487 8 the the DT cord-015569-vy49r1zd 487 9 jellies jelly NNS cord-015569-vy49r1zd 487 10 more more RBR cord-015569-vy49r1zd 487 11 palatable palatable JJ cord-015569-vy49r1zd 487 12 . . . cord-015569-vy49r1zd 488 1 These these DT cord-015569-vy49r1zd 488 2 results result NNS cord-015569-vy49r1zd 488 3 suggested suggest VBD cord-015569-vy49r1zd 488 4 that that IN cord-015569-vy49r1zd 488 5 human human JJ cord-015569-vy49r1zd 488 6 perceptions perception NNS cord-015569-vy49r1zd 488 7 of of IN cord-015569-vy49r1zd 488 8 taste taste NN cord-015569-vy49r1zd 488 9 and and CC cord-015569-vy49r1zd 488 10 food food NN cord-015569-vy49r1zd 488 11 palatability palatability NN cord-015569-vy49r1zd 488 12 were be VBD cord-015569-vy49r1zd 488 13 affected affect VBN cord-015569-vy49r1zd 488 14 not not RB cord-015569-vy49r1zd 488 15 only only RB cord-015569-vy49r1zd 488 16 by by IN cord-015569-vy49r1zd 488 17 foods food NNS cord-015569-vy49r1zd 488 18 but but CC cord-015569-vy49r1zd 488 19 also also RB cord-015569-vy49r1zd 488 20 by by IN cord-015569-vy49r1zd 488 21 contextual contextual JJ cord-015569-vy49r1zd 488 22 and and CC cord-015569-vy49r1zd 488 23 social social JJ cord-015569-vy49r1zd 488 24 variables variable NNS cord-015569-vy49r1zd 488 25 . . . cord-015569-vy49r1zd 489 1 Acknowledgement acknowledgement NN cord-015569-vy49r1zd 489 2 : : : cord-015569-vy49r1zd 489 3 Part part NN cord-015569-vy49r1zd 489 4 of of IN cord-015569-vy49r1zd 489 5 this this DT cord-015569-vy49r1zd 489 6 study study NN cord-015569-vy49r1zd 489 7 was be VBD cord-015569-vy49r1zd 489 8 supported support VBN cord-015569-vy49r1zd 489 9 by by IN cord-015569-vy49r1zd 489 10 a a DT cord-015569-vy49r1zd 489 11 grant grant NN cord-015569-vy49r1zd 489 12 titled title VBN cord-015569-vy49r1zd 489 13 " " `` cord-015569-vy49r1zd 489 14 Effects effect NNS cord-015569-vy49r1zd 489 15 of of IN cord-015569-vy49r1zd 489 16 eating eat VBG cord-015569-vy49r1zd 489 17 with with IN cord-015569-vy49r1zd 489 18 someone someone NN cord-015569-vy49r1zd 489 19 on on IN cord-015569-vy49r1zd 489 20 palatability palatability NN cord-015569-vy49r1zd 489 21 of of IN cord-015569-vy49r1zd 489 22 foods food NNS cord-015569-vy49r1zd 489 23 . . . cord-015569-vy49r1zd 489 24 " " '' cord-015569-vy49r1zd 490 1 from from IN cord-015569-vy49r1zd 490 2 ASAHI ASAHI NNP cord-015569-vy49r1zd 490 3 BREWERIES BREWERIES NNP cord-015569-vy49r1zd 490 4 FOUNDATION FOUNDATION NNP cord-015569-vy49r1zd 490 5 . . . cord-015569-vy49r1zd 491 1 # # $ cord-015569-vy49r1zd 491 2 44 44 CD cord-015569-vy49r1zd 491 3 Taste taste NN cord-015569-vy49r1zd 491 4 and and CC cord-015569-vy49r1zd 491 5 smell smell NN cord-015569-vy49r1zd 491 6 of of IN cord-015569-vy49r1zd 491 7 the the DT cord-015569-vy49r1zd 491 8 bread bread NN cord-015569-vy49r1zd 491 9 made make VBN cord-015569-vy49r1zd 491 10 using use VBG cord-015569-vy49r1zd 491 11 pre pre JJ cord-015569-vy49r1zd 491 12 - - JJ cord-015569-vy49r1zd 491 13 germinated germinate VBN cord-015569-vy49r1zd 491 14 brown brown JJ cord-015569-vy49r1zd 491 15 rice rice NN cord-015569-vy49r1zd 491 16 sake sake NN cord-015569-vy49r1zd 491 17 lees lees NNP cord-015569-vy49r1zd 491 18 Kana Kana NNP cord-015569-vy49r1zd 491 19 Kogiso Kogiso NNP cord-015569-vy49r1zd 491 20 1 1 CD cord-015569-vy49r1zd 492 1 , , , cord-015569-vy49r1zd 492 2 Hiroko Hiroko NNP cord-015569-vy49r1zd 492 3 Nakazawa Nakazawa NNP cord-015569-vy49r1zd 492 4 1 1 CD cord-015569-vy49r1zd 492 5 , , , cord-015569-vy49r1zd 492 6 Yumi Yumi NNP cord-015569-vy49r1zd 492 7 Yoshioka Yoshioka NNP cord-015569-vy49r1zd 492 8 1 1 CD cord-015569-vy49r1zd 492 9 , , , cord-015569-vy49r1zd 492 10 Akiko Akiko NNP cord-015569-vy49r1zd 492 11 Sato Sato NNP cord-015569-vy49r1zd 492 12 1 1 CD cord-015569-vy49r1zd 492 13 and and CC cord-015569-vy49r1zd 492 14 Mitsuo Mitsuo NNP cord-015569-vy49r1zd 492 15 Okazaki Okazaki NNP cord-015569-vy49r1zd 493 1 2 2 LS cord-015569-vy49r1zd 493 2 1 1 CD cord-015569-vy49r1zd 493 3 Faculty Faculty NNP cord-015569-vy49r1zd 493 4 of of IN cord-015569-vy49r1zd 493 5 Human Human NNP cord-015569-vy49r1zd 493 6 Life Life NNP cord-015569-vy49r1zd 493 7 Sciences Sciences NNPS cord-015569-vy49r1zd 493 8 , , , cord-015569-vy49r1zd 493 9 Nagano Nagano NNP cord-015569-vy49r1zd 493 10 Prefectural Prefectural NNP cord-015569-vy49r1zd 493 11 Collage Collage NNP cord-015569-vy49r1zd 493 12 , , , cord-015569-vy49r1zd 493 13 Nagano Nagano NNP cord-015569-vy49r1zd 493 14 , , , cord-015569-vy49r1zd 493 15 Nagano Nagano NNP cord-015569-vy49r1zd 493 16 380 380 CD cord-015569-vy49r1zd 493 17 - - HYPH cord-015569-vy49r1zd 493 18 8525 8525 CD cord-015569-vy49r1zd 493 19 , , , cord-015569-vy49r1zd 493 20 Japan Japan NNP cord-015569-vy49r1zd 493 21 and and CC cord-015569-vy49r1zd 493 22 2 2 CD cord-015569-vy49r1zd 493 23 Okazaki Okazaki NNP cord-015569-vy49r1zd 493 24 Brewer Brewer NNP cord-015569-vy49r1zd 493 25 co co VBD cord-015569-vy49r1zd 493 26 , , , cord-015569-vy49r1zd 493 27 ltd ltd NNP cord-015569-vy49r1zd 493 28 . . NNP cord-015569-vy49r1zd 493 29 , , , cord-015569-vy49r1zd 493 30 Ueda Ueda NNP cord-015569-vy49r1zd 493 31 , , , cord-015569-vy49r1zd 493 32 386 386 CD cord-015569-vy49r1zd 493 33 - - HYPH cord-015569-vy49r1zd 493 34 0012 0012 CD cord-015569-vy49r1zd 494 1 , , , cord-015569-vy49r1zd 494 2 Japan Japan NNP cord-015569-vy49r1zd 494 3 Pre Pre NNP cord-015569-vy49r1zd 494 4 - - VBD cord-015569-vy49r1zd 494 5 germinated germinate VBN cord-015569-vy49r1zd 494 6 brown brown JJ cord-015569-vy49r1zd 494 7 rice rice NN cord-015569-vy49r1zd 494 8 is be VBZ cord-015569-vy49r1zd 494 9 prepared prepare VBN cord-015569-vy49r1zd 494 10 by by IN cord-015569-vy49r1zd 494 11 soaking soak VBG cord-015569-vy49r1zd 494 12 brown brown JJ cord-015569-vy49r1zd 494 13 rice rice NN cord-015569-vy49r1zd 494 14 in in IN cord-015569-vy49r1zd 494 15 water water NN cord-015569-vy49r1zd 494 16 at at IN cord-015569-vy49r1zd 494 17 37 37 CD cord-015569-vy49r1zd 494 18 o o NN cord-015569-vy49r1zd 494 19 C c NN cord-015569-vy49r1zd 494 20 for for IN cord-015569-vy49r1zd 494 21 24 24 CD cord-015569-vy49r1zd 494 22 - - SYM cord-015569-vy49r1zd 494 23 48 48 CD cord-015569-vy49r1zd 494 24 hours hour NNS cord-015569-vy49r1zd 494 25 to to TO cord-015569-vy49r1zd 494 26 initiate initiate VB cord-015569-vy49r1zd 494 27 germination germination NN cord-015569-vy49r1zd 494 28 of of IN cord-015569-vy49r1zd 494 29 sprouts sprout NNS cord-015569-vy49r1zd 494 30 not not RB cord-015569-vy49r1zd 494 31 exceeding exceed VBG cord-015569-vy49r1zd 494 32 0.5 0.5 CD cord-015569-vy49r1zd 494 33 - - SYM cord-015569-vy49r1zd 494 34 1.0 1.0 CD cord-015569-vy49r1zd 494 35 mm mm NN cord-015569-vy49r1zd 494 36 in in IN cord-015569-vy49r1zd 494 37 length length NN cord-015569-vy49r1zd 494 38 . . . cord-015569-vy49r1zd 495 1 In in IN cord-015569-vy49r1zd 495 2 the the DT cord-015569-vy49r1zd 495 3 traditional traditional JJ cord-015569-vy49r1zd 495 4 method method NN cord-015569-vy49r1zd 495 5 of of IN cord-015569-vy49r1zd 495 6 brewing brewing NN cord-015569-vy49r1zd 495 7 sake sake NN cord-015569-vy49r1zd 495 8 , , , cord-015569-vy49r1zd 495 9 rice rice NN cord-015569-vy49r1zd 495 10 bran bran NN cord-015569-vy49r1zd 495 11 and and CC cord-015569-vy49r1zd 495 12 embryo embryo NN cord-015569-vy49r1zd 495 13 bud bud NN cord-015569-vy49r1zd 495 14 are be VBP cord-015569-vy49r1zd 495 15 separated separate VBN cord-015569-vy49r1zd 495 16 from from IN cord-015569-vy49r1zd 495 17 brewer brewer NN cord-015569-vy49r1zd 495 18 's 's POS cord-015569-vy49r1zd 495 19 brown brown JJ cord-015569-vy49r1zd 495 20 rice rice NN cord-015569-vy49r1zd 495 21 during during IN cord-015569-vy49r1zd 495 22 sake sake NN cord-015569-vy49r1zd 495 23 brewing brewing NN cord-015569-vy49r1zd 495 24 in in IN cord-015569-vy49r1zd 495 25 order order NN cord-015569-vy49r1zd 495 26 to to TO cord-015569-vy49r1zd 495 27 remove remove VB cord-015569-vy49r1zd 495 28 the the DT cord-015569-vy49r1zd 495 29 rough rough JJ cord-015569-vy49r1zd 495 30 taste taste NN cord-015569-vy49r1zd 495 31 . . . cord-015569-vy49r1zd 496 1 This this DT cord-015569-vy49r1zd 496 2 study study NN cord-015569-vy49r1zd 496 3 tried try VBD cord-015569-vy49r1zd 496 4 to to TO cord-015569-vy49r1zd 496 5 use use VB cord-015569-vy49r1zd 496 6 sake sake NN cord-015569-vy49r1zd 496 7 lees lee NNS cord-015569-vy49r1zd 496 8 in in IN cord-015569-vy49r1zd 496 9 fermentation fermentation NN cord-015569-vy49r1zd 496 10 with with IN cord-015569-vy49r1zd 496 11 pregerminated pregerminated JJ cord-015569-vy49r1zd 496 12 brown brown NNP cord-015569-vy49r1zd 496 13 rice rice NNP cord-015569-vy49r1zd 496 14 , , , cord-015569-vy49r1zd 496 15 since since IN cord-015569-vy49r1zd 496 16 the the DT cord-015569-vy49r1zd 496 17 sake sake NN cord-015569-vy49r1zd 496 18 made make VBN cord-015569-vy49r1zd 496 19 from from IN cord-015569-vy49r1zd 496 20 pre pre JJ cord-015569-vy49r1zd 496 21 - - JJ cord-015569-vy49r1zd 496 22 germinated germinate VBN cord-015569-vy49r1zd 496 23 brown brown JJ cord-015569-vy49r1zd 496 24 rice rice NN cord-015569-vy49r1zd 496 25 has have VBZ cord-015569-vy49r1zd 496 26 hardly hardly RB cord-015569-vy49r1zd 496 27 appeared appear VBN cord-015569-vy49r1zd 496 28 on on IN cord-015569-vy49r1zd 496 29 the the DT cord-015569-vy49r1zd 496 30 market market NN cord-015569-vy49r1zd 496 31 . . . cord-015569-vy49r1zd 497 1 Also also RB cord-015569-vy49r1zd 497 2 , , , cord-015569-vy49r1zd 497 3 the the DT cord-015569-vy49r1zd 497 4 use use NN cord-015569-vy49r1zd 497 5 and and CC cord-015569-vy49r1zd 497 6 benefit benefit NN cord-015569-vy49r1zd 497 7 of of IN cord-015569-vy49r1zd 497 8 pre pre JJ cord-015569-vy49r1zd 497 9 - - JJ cord-015569-vy49r1zd 497 10 germinated germinate VBN cord-015569-vy49r1zd 497 11 brown brown JJ cord-015569-vy49r1zd 497 12 rice rice NN cord-015569-vy49r1zd 497 13 - - HYPH cord-015569-vy49r1zd 497 14 made make VBN cord-015569-vy49r1zd 497 15 sake sake NN cord-015569-vy49r1zd 497 16 and and CC cord-015569-vy49r1zd 497 17 sake sake NN cord-015569-vy49r1zd 497 18 lees lee NNS cord-015569-vy49r1zd 497 19 have have VBP cord-015569-vy49r1zd 497 20 not not RB cord-015569-vy49r1zd 497 21 been be VBN cord-015569-vy49r1zd 497 22 reported report VBN cord-015569-vy49r1zd 497 23 . . . cord-015569-vy49r1zd 498 1 In in IN cord-015569-vy49r1zd 498 2 this this DT cord-015569-vy49r1zd 498 3 study study NN cord-015569-vy49r1zd 498 4 , , , cord-015569-vy49r1zd 498 5 we -PRON- PRP cord-015569-vy49r1zd 498 6 made make VBD cord-015569-vy49r1zd 498 7 sensory sensory JJ cord-015569-vy49r1zd 498 8 evaluation evaluation NN cord-015569-vy49r1zd 498 9 to to TO cord-015569-vy49r1zd 498 10 measure measure VB cord-015569-vy49r1zd 498 11 the the DT cord-015569-vy49r1zd 498 12 difference difference NN cord-015569-vy49r1zd 498 13 in in IN cord-015569-vy49r1zd 498 14 taste taste NN cord-015569-vy49r1zd 498 15 and and CC cord-015569-vy49r1zd 498 16 smell smell NN cord-015569-vy49r1zd 498 17 between between IN cord-015569-vy49r1zd 498 18 bread bread NN cord-015569-vy49r1zd 498 19 made make VBN cord-015569-vy49r1zd 498 20 using use VBG cord-015569-vy49r1zd 498 21 normal normal JJ cord-015569-vy49r1zd 498 22 sake sake NN cord-015569-vy49r1zd 498 23 lees lee NNS cord-015569-vy49r1zd 498 24 and and CC cord-015569-vy49r1zd 498 25 bread bread NN cord-015569-vy49r1zd 498 26 made make VBN cord-015569-vy49r1zd 498 27 using use VBG cord-015569-vy49r1zd 498 28 pre pre JJ cord-015569-vy49r1zd 498 29 - - JJ cord-015569-vy49r1zd 498 30 germinated germinate VBN cord-015569-vy49r1zd 498 31 brown brown JJ cord-015569-vy49r1zd 498 32 rice rice NN cord-015569-vy49r1zd 498 33 sake sake NN cord-015569-vy49r1zd 498 34 lees lees NNP cord-015569-vy49r1zd 498 35 . . . cord-015569-vy49r1zd 499 1 The the DT cord-015569-vy49r1zd 499 2 result result NN cord-015569-vy49r1zd 499 3 showed show VBD cord-015569-vy49r1zd 499 4 that that IN cord-015569-vy49r1zd 499 5 the the DT cord-015569-vy49r1zd 499 6 bread bread NN cord-015569-vy49r1zd 499 7 made make VBN cord-015569-vy49r1zd 499 8 with with IN cord-015569-vy49r1zd 499 9 pre pre JJ cord-015569-vy49r1zd 499 10 - - JJ cord-015569-vy49r1zd 499 11 germinated germinate VBN cord-015569-vy49r1zd 499 12 brown brown JJ cord-015569-vy49r1zd 499 13 rice rice NN cord-015569-vy49r1zd 499 14 sake sake NN cord-015569-vy49r1zd 499 15 lees lees NNP cord-015569-vy49r1zd 499 16 had have VBD cord-015569-vy49r1zd 499 17 significantly significantly RB cord-015569-vy49r1zd 499 18 better well JJR cord-015569-vy49r1zd 499 19 smell smell NN cord-015569-vy49r1zd 499 20 ( ( -LRB- cord-015569-vy49r1zd 499 21 p p NN cord-015569-vy49r1zd 499 22 = = SYM cord-015569-vy49r1zd 499 23 0.0365 0.0365 CD cord-015569-vy49r1zd 499 24 ) ) -RRB- cord-015569-vy49r1zd 499 25 and and CC cord-015569-vy49r1zd 499 26 stronger strong JJR cord-015569-vy49r1zd 499 27 sake sake NN cord-015569-vy49r1zd 500 1 lees lees NNP cord-015569-vy49r1zd 500 2 smell smell NNP cord-015569-vy49r1zd 500 3 ( ( -LRB- cord-015569-vy49r1zd 500 4 p p NN cord-015569-vy49r1zd 500 5 = = SYM cord-015569-vy49r1zd 500 6 0.0026 0.0026 CD cord-015569-vy49r1zd 500 7 ) ) -RRB- cord-015569-vy49r1zd 500 8 as as RB cord-015569-vy49r1zd 500 9 well well RB cord-015569-vy49r1zd 500 10 as as IN cord-015569-vy49r1zd 500 11 a a DT cord-015569-vy49r1zd 500 12 stronger strong JJR cord-015569-vy49r1zd 500 13 sake sake NN cord-015569-vy49r1zd 500 14 less less JJR cord-015569-vy49r1zd 500 15 taste taste NN cord-015569-vy49r1zd 500 16 ( ( -LRB- cord-015569-vy49r1zd 500 17 p p NN cord-015569-vy49r1zd 500 18 < < XX cord-015569-vy49r1zd 500 19 0.0001 0.0001 CD cord-015569-vy49r1zd 500 20 ) ) -RRB- cord-015569-vy49r1zd 500 21 than than IN cord-015569-vy49r1zd 500 22 the the DT cord-015569-vy49r1zd 500 23 bread bread NN cord-015569-vy49r1zd 500 24 made make VBN cord-015569-vy49r1zd 500 25 with with IN cord-015569-vy49r1zd 500 26 normal normal JJ cord-015569-vy49r1zd 500 27 sake sake NN cord-015569-vy49r1zd 500 28 lees lees NNP cord-015569-vy49r1zd 500 29 . . . cord-015569-vy49r1zd 501 1 The the DT cord-015569-vy49r1zd 501 2 complex complex JJ cord-015569-vy49r1zd 501 3 flavor flavor NN cord-015569-vy49r1zd 501 4 ( ( -LRB- cord-015569-vy49r1zd 501 5 p p NN cord-015569-vy49r1zd 501 6 = = SYM cord-015569-vy49r1zd 501 7 0.0587 0.0587 CD cord-015569-vy49r1zd 501 8 ) ) -RRB- cord-015569-vy49r1zd 501 9 and and CC cord-015569-vy49r1zd 501 10 saltiness saltiness NN cord-015569-vy49r1zd 501 11 ( ( -LRB- cord-015569-vy49r1zd 501 12 p p NN cord-015569-vy49r1zd 501 13 = = SYM cord-015569-vy49r1zd 501 14 0.0511 0.0511 CD cord-015569-vy49r1zd 501 15 ) ) -RRB- cord-015569-vy49r1zd 501 16 of of IN cord-015569-vy49r1zd 501 17 the the DT cord-015569-vy49r1zd 501 18 bread bread NN cord-015569-vy49r1zd 501 19 made make VBN cord-015569-vy49r1zd 501 20 with with IN cord-015569-vy49r1zd 501 21 pre pre JJ cord-015569-vy49r1zd 501 22 - - JJ cord-015569-vy49r1zd 501 23 germinated germinate VBN cord-015569-vy49r1zd 501 24 brown brown JJ cord-015569-vy49r1zd 501 25 rice rice NN cord-015569-vy49r1zd 501 26 sake sake NN cord-015569-vy49r1zd 501 27 lees lees NNP cord-015569-vy49r1zd 501 28 tended tend VBD cord-015569-vy49r1zd 501 29 to to TO cord-015569-vy49r1zd 501 30 be be VB cord-015569-vy49r1zd 501 31 stronger strong JJR cord-015569-vy49r1zd 501 32 than than IN cord-015569-vy49r1zd 501 33 that that DT cord-015569-vy49r1zd 501 34 of of IN cord-015569-vy49r1zd 501 35 the the DT cord-015569-vy49r1zd 501 36 made make VBN cord-015569-vy49r1zd 501 37 with with IN cord-015569-vy49r1zd 501 38 normal normal JJ cord-015569-vy49r1zd 501 39 sake sake NN cord-015569-vy49r1zd 501 40 lees lees NNP cord-015569-vy49r1zd 501 41 . . . cord-015569-vy49r1zd 502 1 Female female JJ cord-015569-vy49r1zd 502 2 college college NN cord-015569-vy49r1zd 502 3 studentsÕ studentsÕ NNP cord-015569-vy49r1zd 502 4 preference preference NN cord-015569-vy49r1zd 502 5 to to IN cord-015569-vy49r1zd 502 6 steamed steam VBN cord-015569-vy49r1zd 502 7 and and CC cord-015569-vy49r1zd 502 8 cured cure VBN cord-015569-vy49r1zd 502 9 slices slice NNS cord-015569-vy49r1zd 502 10 of of IN cord-015569-vy49r1zd 502 11 sweet sweet JJ cord-015569-vy49r1zd 502 12 potato potato NN cord-015569-vy49r1zd 502 13 was be VBD cord-015569-vy49r1zd 502 14 evaluated evaluate VBN cord-015569-vy49r1zd 502 15 to to TO cord-015569-vy49r1zd 502 16 find find VB cord-015569-vy49r1zd 502 17 their -PRON- PRP$ cord-015569-vy49r1zd 502 18 sensory sensory JJ cord-015569-vy49r1zd 502 19 characteristics characteristic NNS cord-015569-vy49r1zd 502 20 . . . cord-015569-vy49r1zd 503 1 Evaluation evaluation NN cord-015569-vy49r1zd 503 2 was be VBD cord-015569-vy49r1zd 503 3 carried carry VBN cord-015569-vy49r1zd 503 4 out out RP cord-015569-vy49r1zd 503 5 with with IN cord-015569-vy49r1zd 503 6 the the DT cord-015569-vy49r1zd 503 7 10 10 CD cord-015569-vy49r1zd 503 8 sweet sweet JJ cord-015569-vy49r1zd 503 9 potato potato NN cord-015569-vy49r1zd 503 10 cultivars cultivar NNS cord-015569-vy49r1zd 503 11 and and CC cord-015569-vy49r1zd 503 12 lines line NNS cord-015569-vy49r1zd 503 13 , , , cord-015569-vy49r1zd 503 14 Tamayutaka Tamayutaka NNP cord-015569-vy49r1zd 503 15 , , , cord-015569-vy49r1zd 503 16 Izumi13 Izumi13 NNP cord-015569-vy49r1zd 503 17 , , , cord-015569-vy49r1zd 503 18 Hoshikirari Hoshikirari NNP cord-015569-vy49r1zd 503 19 , , , cord-015569-vy49r1zd 503 20 Kanto131 Kanto131 NNP cord-015569-vy49r1zd 503 21 , , , cord-015569-vy49r1zd 503 22 Tamaotome Tamaotome NNP cord-015569-vy49r1zd 503 23 , , , cord-015569-vy49r1zd 503 24 Quick Quick NNP cord-015569-vy49r1zd 503 25 Sweet Sweet NNP cord-015569-vy49r1zd 503 26 , , , cord-015569-vy49r1zd 503 27 Hitachi Hitachi NNP cord-015569-vy49r1zd 503 28 Red Red NNP cord-015569-vy49r1zd 503 29 , , , cord-015569-vy49r1zd 503 30 Hamakomachi Hamakomachi NNP cord-015569-vy49r1zd 503 31 , , , cord-015569-vy49r1zd 503 32 Purple Purple NNP cord-015569-vy49r1zd 503 33 Sweet Sweet NNP cord-015569-vy49r1zd 503 34 Lord Lord NNP cord-015569-vy49r1zd 503 35 and and CC cord-015569-vy49r1zd 503 36 Sakukei20 Sakukei20 NNP cord-015569-vy49r1zd 503 37 in in IN cord-015569-vy49r1zd 503 38 terms term NNS cord-015569-vy49r1zd 503 39 of of IN cord-015569-vy49r1zd 503 40 appearance appearance NN cord-015569-vy49r1zd 503 41 , , , cord-015569-vy49r1zd 503 42 fragrance fragrance NN cord-015569-vy49r1zd 503 43 , , , cord-015569-vy49r1zd 503 44 texture texture NN cord-015569-vy49r1zd 503 45 and and CC cord-015569-vy49r1zd 503 46 taste taste NN cord-015569-vy49r1zd 503 47 by by IN cord-015569-vy49r1zd 503 48 a a DT cord-015569-vy49r1zd 503 49 rank rank NN cord-015569-vy49r1zd 503 50 - - HYPH cord-015569-vy49r1zd 503 51 scoring scoring NN cord-015569-vy49r1zd 503 52 method method NN cord-015569-vy49r1zd 503 53 . . . cord-015569-vy49r1zd 504 1 The the DT cord-015569-vy49r1zd 504 2 most most RBS cord-015569-vy49r1zd 504 3 preferable preferable JJ cord-015569-vy49r1zd 504 4 cultivars cultivar NNS cord-015569-vy49r1zd 504 5 were be VBD cord-015569-vy49r1zd 504 6 Hoshikirari Hoshikirari NNP cord-015569-vy49r1zd 504 7 , , , cord-015569-vy49r1zd 504 8 Tamaotome Tamaotome NNP cord-015569-vy49r1zd 504 9 , , , cord-015569-vy49r1zd 504 10 and and CC cord-015569-vy49r1zd 504 11 Kanto131 Kanto131 NNP cord-015569-vy49r1zd 504 12 ; ; : cord-015569-vy49r1zd 504 13 sweetness sweetness NN cord-015569-vy49r1zd 504 14 greatly greatly RB cord-015569-vy49r1zd 504 15 contributed contribute VBD cord-015569-vy49r1zd 504 16 to to IN cord-015569-vy49r1zd 504 17 the the DT cord-015569-vy49r1zd 504 18 taste taste NN cord-015569-vy49r1zd 504 19 of of IN cord-015569-vy49r1zd 504 20 the the DT cord-015569-vy49r1zd 504 21 steamed steamed JJ cord-015569-vy49r1zd 504 22 and and CC cord-015569-vy49r1zd 504 23 cured cure VBN cord-015569-vy49r1zd 504 24 slices slice NNS cord-015569-vy49r1zd 504 25 of of IN cord-015569-vy49r1zd 504 26 these these DT cord-015569-vy49r1zd 504 27 samples sample NNS cord-015569-vy49r1zd 504 28 , , , cord-015569-vy49r1zd 504 29 while while IN cord-015569-vy49r1zd 504 30 appearance appearance NN cord-015569-vy49r1zd 504 31 and and CC cord-015569-vy49r1zd 504 32 texture texture NN cord-015569-vy49r1zd 504 33 somehow somehow RB cord-015569-vy49r1zd 504 34 influenced influence VBD cord-015569-vy49r1zd 504 35 their -PRON- PRP$ cord-015569-vy49r1zd 504 36 taste taste NN cord-015569-vy49r1zd 504 37 scores score NNS cord-015569-vy49r1zd 504 38 . . . cord-015569-vy49r1zd 505 1 Fish fish NN cord-015569-vy49r1zd 505 2 flakes flake NNS cord-015569-vy49r1zd 505 3 are be VBP cord-015569-vy49r1zd 505 4 one one CD cord-015569-vy49r1zd 505 5 of of IN cord-015569-vy49r1zd 505 6 the the DT cord-015569-vy49r1zd 505 7 traditional traditional JJ cord-015569-vy49r1zd 505 8 Japanese japanese JJ cord-015569-vy49r1zd 505 9 ingredients ingredient NNS cord-015569-vy49r1zd 505 10 for for IN cord-015569-vy49r1zd 505 11 dashi dashi NNS cord-015569-vy49r1zd 505 12 . . . cord-015569-vy49r1zd 506 1 Various various JJ cord-015569-vy49r1zd 506 2 methods method NNS cord-015569-vy49r1zd 506 3 are be VBP cord-015569-vy49r1zd 506 4 used use VBN cord-015569-vy49r1zd 506 5 to to TO cord-015569-vy49r1zd 506 6 extract extract VB cord-015569-vy49r1zd 506 7 dashi dashi NNS cord-015569-vy49r1zd 506 8 depending depend VBG cord-015569-vy49r1zd 506 9 on on IN cord-015569-vy49r1zd 506 10 the the DT cord-015569-vy49r1zd 506 11 thickness thickness NN cord-015569-vy49r1zd 506 12 of of IN cord-015569-vy49r1zd 506 13 flake flake NN cord-015569-vy49r1zd 506 14 . . . cord-015569-vy49r1zd 507 1 Especially especially RB cord-015569-vy49r1zd 507 2 , , , cord-015569-vy49r1zd 507 3 the the DT cord-015569-vy49r1zd 507 4 thick thick JJ cord-015569-vy49r1zd 507 5 type type NN cord-015569-vy49r1zd 507 6 flake flake NN cord-015569-vy49r1zd 507 7 that that WDT cord-015569-vy49r1zd 507 8 is be VBZ cord-015569-vy49r1zd 507 9 often often RB cord-015569-vy49r1zd 507 10 used use VBN cord-015569-vy49r1zd 507 11 for for IN cord-015569-vy49r1zd 507 12 Soba soba NN cord-015569-vy49r1zd 507 13 noodle noodle NN cord-015569-vy49r1zd 507 14 sauce sauce NN cord-015569-vy49r1zd 507 15 requires require VBZ cord-015569-vy49r1zd 507 16 around around RB cord-015569-vy49r1zd 507 17 30 30 CD cord-015569-vy49r1zd 507 18 minutes minute NNS cord-015569-vy49r1zd 507 19 of of IN cord-015569-vy49r1zd 507 20 cooking cooking NN cord-015569-vy49r1zd 507 21 time time NN cord-015569-vy49r1zd 507 22 and and CC cord-015569-vy49r1zd 507 23 extracting extract VBG cord-015569-vy49r1zd 507 24 conditions condition NNS cord-015569-vy49r1zd 507 25 vary vary VBP cord-015569-vy49r1zd 507 26 as as RB cord-015569-vy49r1zd 507 27 well well RB cord-015569-vy49r1zd 507 28 . . . cord-015569-vy49r1zd 508 1 The the DT cord-015569-vy49r1zd 508 2 energy energy NN cord-015569-vy49r1zd 508 3 saving saving NN cord-015569-vy49r1zd 508 4 has have VBZ cord-015569-vy49r1zd 508 5 become become VBN cord-015569-vy49r1zd 508 6 recent recent JJ cord-015569-vy49r1zd 508 7 tendency tendency NN cord-015569-vy49r1zd 508 8 even even RB cord-015569-vy49r1zd 508 9 in in IN cord-015569-vy49r1zd 508 10 culinary culinary JJ cord-015569-vy49r1zd 508 11 field field NN cord-015569-vy49r1zd 508 12 , , , cord-015569-vy49r1zd 508 13 and and CC cord-015569-vy49r1zd 508 14 we -PRON- PRP cord-015569-vy49r1zd 508 15 focused focus VBD cord-015569-vy49r1zd 508 16 on on IN cord-015569-vy49r1zd 508 17 a a DT cord-015569-vy49r1zd 508 18 cooking cooking NN cord-015569-vy49r1zd 508 19 method method NN cord-015569-vy49r1zd 508 20 using use VBG cord-015569-vy49r1zd 508 21 remaining remain VBG cord-015569-vy49r1zd 508 22 heat heat NN cord-015569-vy49r1zd 508 23 . . . cord-015569-vy49r1zd 509 1 We -PRON- PRP cord-015569-vy49r1zd 509 2 analyzed analyze VBD cord-015569-vy49r1zd 509 3 the the DT cord-015569-vy49r1zd 509 4 free free JJ cord-015569-vy49r1zd 509 5 amino amino NN cord-015569-vy49r1zd 509 6 acid acid NN cord-015569-vy49r1zd 509 7 and and CC cord-015569-vy49r1zd 509 8 5#-IMP 5#-imp NN cord-015569-vy49r1zd 509 9 . . . cord-015569-vy49r1zd 510 1 Sensory sensory JJ cord-015569-vy49r1zd 510 2 evaluation evaluation NN cord-015569-vy49r1zd 510 3 was be VBD cord-015569-vy49r1zd 510 4 carried carry VBN cord-015569-vy49r1zd 510 5 out out RP cord-015569-vy49r1zd 510 6 at at IN cord-015569-vy49r1zd 510 7 the the DT cord-015569-vy49r1zd 510 8 same same JJ cord-015569-vy49r1zd 510 9 time time NN cord-015569-vy49r1zd 510 10 . . . cord-015569-vy49r1zd 511 1 As as IN cord-015569-vy49r1zd 511 2 a a DT cord-015569-vy49r1zd 511 3 result result NN cord-015569-vy49r1zd 511 4 , , , cord-015569-vy49r1zd 511 5 we -PRON- PRP cord-015569-vy49r1zd 511 6 can can MD cord-015569-vy49r1zd 511 7 suggest suggest VB cord-015569-vy49r1zd 511 8 that that IN cord-015569-vy49r1zd 511 9 there there EX cord-015569-vy49r1zd 511 10 is be VBZ cord-015569-vy49r1zd 511 11 a a DT cord-015569-vy49r1zd 511 12 method method NN cord-015569-vy49r1zd 511 13 for for IN cord-015569-vy49r1zd 511 14 extracting extract VBG cord-015569-vy49r1zd 511 15 the the DT cord-015569-vy49r1zd 511 16 most most RBS cord-015569-vy49r1zd 511 17 effective effective JJ cord-015569-vy49r1zd 511 18 use use NN cord-015569-vy49r1zd 511 19 of of IN cord-015569-vy49r1zd 511 20 remaining remain VBG cord-015569-vy49r1zd 511 21 heat heat NN cord-015569-vy49r1zd 511 22 for for IN cord-015569-vy49r1zd 511 23 25 25 CD cord-015569-vy49r1zd 511 24 minutes minute NNS cord-015569-vy49r1zd 511 25 after after IN cord-015569-vy49r1zd 511 26 heating heat VBG cord-015569-vy49r1zd 511 27 for for IN cord-015569-vy49r1zd 511 28 5 5 CD cord-015569-vy49r1zd 511 29 minutes minute NNS cord-015569-vy49r1zd 511 30 . . . cord-015569-vy49r1zd 512 1 We -PRON- PRP cord-015569-vy49r1zd 512 2 were be VBD cord-015569-vy49r1zd 512 3 able able JJ cord-015569-vy49r1zd 512 4 to to TO cord-015569-vy49r1zd 512 5 explain explain VB cord-015569-vy49r1zd 512 6 the the DT cord-015569-vy49r1zd 512 7 taste taste NN cord-015569-vy49r1zd 512 8 improvement improvement NN cord-015569-vy49r1zd 512 9 from from IN cord-015569-vy49r1zd 512 10 the the DT cord-015569-vy49r1zd 512 11 amino amino NN cord-015569-vy49r1zd 512 12 acid acid NN cord-015569-vy49r1zd 512 13 composition composition NN cord-015569-vy49r1zd 512 14 determined determine VBN cord-015569-vy49r1zd 512 15 by by IN cord-015569-vy49r1zd 512 16 AccQ- AccQ- NNP cord-015569-vy49r1zd 513 1 Tag Tag NNP cord-015569-vy49r1zd 513 2 TM TM NNP cord-015569-vy49r1zd 513 3 Ultra ultra JJ cord-015569-vy49r1zd 513 4 method method NN cord-015569-vy49r1zd 513 5 . . . cord-015569-vy49r1zd 514 1 This this DT cord-015569-vy49r1zd 514 2 condition condition NN cord-015569-vy49r1zd 514 3 can can MD cord-015569-vy49r1zd 514 4 be be VB cord-015569-vy49r1zd 514 5 considered consider VBN cord-015569-vy49r1zd 514 6 effective effective JJ cord-015569-vy49r1zd 514 7 for for IN cord-015569-vy49r1zd 514 8 both both DT cord-015569-vy49r1zd 514 9 energy energy NN cord-015569-vy49r1zd 514 10 saving saving NN cord-015569-vy49r1zd 514 11 and and CC cord-015569-vy49r1zd 514 12 flavor flavor NN cord-015569-vy49r1zd 514 13 improvement improvement NN cord-015569-vy49r1zd 514 14 of of IN cord-015569-vy49r1zd 514 15 dashi dashi NN cord-015569-vy49r1zd 514 16 . . . cord-015569-vy49r1zd 515 1 Oolong oolong NN cord-015569-vy49r1zd 515 2 tea tea NN cord-015569-vy49r1zd 515 3 is be VBZ cord-015569-vy49r1zd 515 4 usually usually RB cord-015569-vy49r1zd 515 5 served serve VBN cord-015569-vy49r1zd 515 6 with with IN cord-015569-vy49r1zd 515 7 oil oil NN cord-015569-vy49r1zd 515 8 - - HYPH cord-015569-vy49r1zd 515 9 rich rich JJ cord-015569-vy49r1zd 515 10 Chinese chinese JJ cord-015569-vy49r1zd 515 11 food food NN cord-015569-vy49r1zd 515 12 . . . cord-015569-vy49r1zd 516 1 Our -PRON- PRP$ cord-015569-vy49r1zd 516 2 group group NN cord-015569-vy49r1zd 516 3 has have VBZ cord-015569-vy49r1zd 516 4 been be VBN cord-015569-vy49r1zd 516 5 studying study VBG cord-015569-vy49r1zd 516 6 on on IN cord-015569-vy49r1zd 516 7 the the DT cord-015569-vy49r1zd 516 8 mechanism mechanism NN cord-015569-vy49r1zd 516 9 of of IN cord-015569-vy49r1zd 516 10 oil oil NN cord-015569-vy49r1zd 516 11 rinsing rinsing NN cord-015569-vy49r1zd 516 12 in in IN cord-015569-vy49r1zd 516 13 the the DT cord-015569-vy49r1zd 516 14 mouth mouth NN cord-015569-vy49r1zd 516 15 and and CC cord-015569-vy49r1zd 516 16 , , , cord-015569-vy49r1zd 516 17 in in IN cord-015569-vy49r1zd 516 18 particular particular JJ cord-015569-vy49r1zd 516 19 , , , cord-015569-vy49r1zd 516 20 on on IN cord-015569-vy49r1zd 516 21 the the DT cord-015569-vy49r1zd 516 22 interactions interaction NNS cord-015569-vy49r1zd 516 23 between between IN cord-015569-vy49r1zd 516 24 oolong oolong NN cord-015569-vy49r1zd 516 25 tea tea NN cord-015569-vy49r1zd 516 26 components component NNS cord-015569-vy49r1zd 516 27 and and CC cord-015569-vy49r1zd 516 28 oil oil NN cord-015569-vy49r1zd 516 29 . . . cord-015569-vy49r1zd 517 1 Our -PRON- PRP$ cord-015569-vy49r1zd 517 2 previous previous JJ cord-015569-vy49r1zd 517 3 studies study NNS cord-015569-vy49r1zd 517 4 showed show VBD cord-015569-vy49r1zd 517 5 that that IN cord-015569-vy49r1zd 517 6 oolong oolong NN cord-015569-vy49r1zd 517 7 tea tea NN cord-015569-vy49r1zd 517 8 had have VBD cord-015569-vy49r1zd 517 9 a a DT cord-015569-vy49r1zd 517 10 higher high JJR cord-015569-vy49r1zd 517 11 affinity affinity NN cord-015569-vy49r1zd 517 12 for for IN cord-015569-vy49r1zd 517 13 oil oil NN cord-015569-vy49r1zd 517 14 than than IN cord-015569-vy49r1zd 517 15 deionized deionize VBN cord-015569-vy49r1zd 517 16 water water NN cord-015569-vy49r1zd 517 17 , , , cord-015569-vy49r1zd 517 18 mineral mineral NN cord-015569-vy49r1zd 517 19 water water NN cord-015569-vy49r1zd 517 20 and and CC cord-015569-vy49r1zd 517 21 green green JJ cord-015569-vy49r1zd 517 22 tea tea NN cord-015569-vy49r1zd 517 23 did do VBD cord-015569-vy49r1zd 517 24 . . . cord-015569-vy49r1zd 518 1 It -PRON- PRP cord-015569-vy49r1zd 518 2 may may MD cord-015569-vy49r1zd 518 3 thus thus RB cord-015569-vy49r1zd 518 4 be be VB cord-015569-vy49r1zd 518 5 more more RBR cord-015569-vy49r1zd 518 6 effective effective JJ cord-015569-vy49r1zd 518 7 in in IN cord-015569-vy49r1zd 518 8 washing wash VBG cord-015569-vy49r1zd 518 9 out out RP cord-015569-vy49r1zd 518 10 remaining remain VBG cord-015569-vy49r1zd 518 11 oil oil NN cord-015569-vy49r1zd 518 12 from from IN cord-015569-vy49r1zd 518 13 the the DT cord-015569-vy49r1zd 518 14 mouth mouth NN cord-015569-vy49r1zd 518 15 . . . cord-015569-vy49r1zd 519 1 The the DT cord-015569-vy49r1zd 519 2 objective objective NN cord-015569-vy49r1zd 519 3 of of IN cord-015569-vy49r1zd 519 4 this this DT cord-015569-vy49r1zd 519 5 study study NN cord-015569-vy49r1zd 519 6 is be VBZ cord-015569-vy49r1zd 519 7 to to TO cord-015569-vy49r1zd 519 8 determine determine VB cord-015569-vy49r1zd 519 9 the the DT cord-015569-vy49r1zd 519 10 effective effective JJ cord-015569-vy49r1zd 519 11 oolong oolong NN cord-015569-vy49r1zd 519 12 tea tea NN cord-015569-vy49r1zd 519 13 components component NNS cord-015569-vy49r1zd 519 14 contributing contribute VBG cord-015569-vy49r1zd 519 15 to to IN cord-015569-vy49r1zd 519 16 removing remove VBG cord-015569-vy49r1zd 519 17 the the DT cord-015569-vy49r1zd 519 18 residual residual JJ cord-015569-vy49r1zd 519 19 oily oily JJ cord-015569-vy49r1zd 519 20 sensation sensation NN cord-015569-vy49r1zd 519 21 . . . cord-015569-vy49r1zd 520 1 For for IN cord-015569-vy49r1zd 520 2 the the DT cord-015569-vy49r1zd 520 3 human human JJ cord-015569-vy49r1zd 520 4 sensory sensory JJ cord-015569-vy49r1zd 520 5 evaluation evaluation NN cord-015569-vy49r1zd 520 6 , , , cord-015569-vy49r1zd 520 7 sweetened sweeten VBN cord-015569-vy49r1zd 520 8 whipped whip VBN cord-015569-vy49r1zd 520 9 cream cream NN cord-015569-vy49r1zd 520 10 was be VBD cord-015569-vy49r1zd 520 11 used use VBN cord-015569-vy49r1zd 520 12 as as IN cord-015569-vy49r1zd 520 13 an an DT cord-015569-vy49r1zd 520 14 aliment aliment NN cord-015569-vy49r1zd 520 15 , , , cord-015569-vy49r1zd 520 16 and and CC cord-015569-vy49r1zd 520 17 mineral mineral NN cord-015569-vy49r1zd 520 18 water water NN cord-015569-vy49r1zd 520 19 or or CC cord-015569-vy49r1zd 520 20 oolong oolong NN cord-015569-vy49r1zd 520 21 tea tea NN cord-015569-vy49r1zd 520 22 was be VBD cord-015569-vy49r1zd 520 23 used use VBN cord-015569-vy49r1zd 520 24 as as IN cord-015569-vy49r1zd 520 25 a a DT cord-015569-vy49r1zd 520 26 washer washer NN cord-015569-vy49r1zd 520 27 , , , cord-015569-vy49r1zd 520 28 with with IN cord-015569-vy49r1zd 520 29 the the DT cord-015569-vy49r1zd 520 30 result result NN cord-015569-vy49r1zd 520 31 that that IN cord-015569-vy49r1zd 520 32 oolong oolong NN cord-015569-vy49r1zd 520 33 tea tea NN cord-015569-vy49r1zd 520 34 more more RBR cord-015569-vy49r1zd 520 35 effectively effectively RB cord-015569-vy49r1zd 520 36 reduced reduce VBD cord-015569-vy49r1zd 520 37 the the DT cord-015569-vy49r1zd 520 38 sense sense NN cord-015569-vy49r1zd 520 39 of of IN cord-015569-vy49r1zd 520 40 residual residual JJ cord-015569-vy49r1zd 520 41 oiliness oiliness NN cord-015569-vy49r1zd 520 42 . . . cord-015569-vy49r1zd 521 1 An an DT cord-015569-vy49r1zd 521 2 aqueous aqueous JJ cord-015569-vy49r1zd 521 3 solution solution NN cord-015569-vy49r1zd 521 4 of of IN cord-015569-vy49r1zd 521 5 Epigallocatechin Epigallocatechin NNP cord-015569-vy49r1zd 521 6 gallate gallate NNP cord-015569-vy49r1zd 521 7 ( ( -LRB- cord-015569-vy49r1zd 521 8 EGCG EGCG NNP cord-015569-vy49r1zd 521 9 ) ) -RRB- cord-015569-vy49r1zd 521 10 and and CC cord-015569-vy49r1zd 521 11 epigallocatechin epigallocatechin NNP cord-015569-vy49r1zd 521 12 ( ( -LRB- cord-015569-vy49r1zd 521 13 EGC EGC NNP cord-015569-vy49r1zd 521 14 ) ) -RRB- cord-015569-vy49r1zd 521 15 as as IN cord-015569-vy49r1zd 521 16 tea tea NN cord-015569-vy49r1zd 521 17 constituents constituent NNS cord-015569-vy49r1zd 521 18 was be VBD cord-015569-vy49r1zd 521 19 used use VBN cord-015569-vy49r1zd 521 20 to to TO cord-015569-vy49r1zd 521 21 measure measure VB cord-015569-vy49r1zd 521 22 its -PRON- PRP$ cord-015569-vy49r1zd 521 23 interfacial interfacial JJ cord-015569-vy49r1zd 521 24 tension tension NN cord-015569-vy49r1zd 521 25 activity activity NN cord-015569-vy49r1zd 521 26 in in IN cord-015569-vy49r1zd 521 27 the the DT cord-015569-vy49r1zd 521 28 presence presence NN cord-015569-vy49r1zd 521 29 of of IN cord-015569-vy49r1zd 521 30 soybean soybean NN cord-015569-vy49r1zd 521 31 oil oil NN cord-015569-vy49r1zd 521 32 by by IN cord-015569-vy49r1zd 521 33 a a DT cord-015569-vy49r1zd 521 34 face face NN cord-015569-vy49r1zd 521 35 surface surface NN cord-015569-vy49r1zd 521 36 tensiometer tensiometer NN cord-015569-vy49r1zd 521 37 . . . cord-015569-vy49r1zd 522 1 Also also RB cord-015569-vy49r1zd 522 2 , , , cord-015569-vy49r1zd 522 3 we -PRON- PRP cord-015569-vy49r1zd 522 4 emulsified emulsify VBD cord-015569-vy49r1zd 522 5 soybean soybean NN cord-015569-vy49r1zd 522 6 oil oil NN cord-015569-vy49r1zd 522 7 with with IN cord-015569-vy49r1zd 522 8 EGCG EGCG NNP cord-015569-vy49r1zd 522 9 or or CC cord-015569-vy49r1zd 522 10 EGC EGC NNP cord-015569-vy49r1zd 522 11 and and CC cord-015569-vy49r1zd 522 12 examined examine VBD cord-015569-vy49r1zd 522 13 the the DT cord-015569-vy49r1zd 522 14 resulting result VBG cord-015569-vy49r1zd 522 15 average average JJ cord-015569-vy49r1zd 522 16 particle particle NN cord-015569-vy49r1zd 522 17 size size NN cord-015569-vy49r1zd 522 18 with with IN cord-015569-vy49r1zd 522 19 a a DT cord-015569-vy49r1zd 522 20 Laser Laser NNP cord-015569-vy49r1zd 522 21 Diffraction diffraction NN cord-015569-vy49r1zd 522 22 Particle particle NN cord-015569-vy49r1zd 522 23 Size size NN cord-015569-vy49r1zd 522 24 Analyzer Analyzer NNP cord-015569-vy49r1zd 522 25 . . . cord-015569-vy49r1zd 523 1 It -PRON- PRP cord-015569-vy49r1zd 523 2 was be VBD cord-015569-vy49r1zd 523 3 found find VBN cord-015569-vy49r1zd 523 4 that that IN cord-015569-vy49r1zd 523 5 EGCG EGCG NNP cord-015569-vy49r1zd 523 6 and and CC cord-015569-vy49r1zd 523 7 EGC EGC NNP cord-015569-vy49r1zd 523 8 did do VBD cord-015569-vy49r1zd 523 9 not not RB cord-015569-vy49r1zd 523 10 influence influence VB cord-015569-vy49r1zd 523 11 the the DT cord-015569-vy49r1zd 523 12 interfacial interfacial JJ cord-015569-vy49r1zd 523 13 tension tension NN cord-015569-vy49r1zd 523 14 and and CC cord-015569-vy49r1zd 523 15 average average JJ cord-015569-vy49r1zd 523 16 particle particle NN cord-015569-vy49r1zd 523 17 size size NN cord-015569-vy49r1zd 523 18 . . . cord-015569-vy49r1zd 524 1 Further further JJ cord-015569-vy49r1zd 524 2 studies study NNS cord-015569-vy49r1zd 524 3 are be VBP cord-015569-vy49r1zd 524 4 required require VBN cord-015569-vy49r1zd 524 5 to to TO cord-015569-vy49r1zd 524 6 find find VB cord-015569-vy49r1zd 524 7 some some DT cord-015569-vy49r1zd 524 8 contributory contributory JJ cord-015569-vy49r1zd 524 9 factor factor NN cord-015569-vy49r1zd 524 10 . . . cord-015569-vy49r1zd 525 1 Commercial commercial JJ cord-015569-vy49r1zd 525 2 granulated granulated JJ cord-015569-vy49r1zd 525 3 sugars sugar NNS cord-015569-vy49r1zd 525 4 are be VBP cord-015569-vy49r1zd 525 5 of of IN cord-015569-vy49r1zd 525 6 99.9 99.9 CD cord-015569-vy49r1zd 525 7 % % NN cord-015569-vy49r1zd 525 8 purity purity NN cord-015569-vy49r1zd 525 9 which which WDT cord-015569-vy49r1zd 525 10 is be VBZ cord-015569-vy49r1zd 525 11 almost almost RB cord-015569-vy49r1zd 525 12 equivalent equivalent JJ cord-015569-vy49r1zd 525 13 to to IN cord-015569-vy49r1zd 525 14 the the DT cord-015569-vy49r1zd 525 15 purity purity NN cord-015569-vy49r1zd 525 16 of of IN cord-015569-vy49r1zd 525 17 a a DT cord-015569-vy49r1zd 525 18 guaranteed guarantee VBN cord-015569-vy49r1zd 525 19 reagent reagent NN cord-015569-vy49r1zd 525 20 - - HYPH cord-015569-vy49r1zd 525 21 grade grade NN cord-015569-vy49r1zd 525 22 sucrose sucrose NN cord-015569-vy49r1zd 525 23 . . . cord-015569-vy49r1zd 526 1 We -PRON- PRP cord-015569-vy49r1zd 526 2 observed observe VBD cord-015569-vy49r1zd 526 3 that that IN cord-015569-vy49r1zd 526 4 commercial commercial JJ cord-015569-vy49r1zd 526 5 sugars sugar NNS cord-015569-vy49r1zd 526 6 were be VBD cord-015569-vy49r1zd 526 7 different different JJ cord-015569-vy49r1zd 526 8 in in IN cord-015569-vy49r1zd 526 9 melting melt VBG cord-015569-vy49r1zd 526 10 point point NN cord-015569-vy49r1zd 526 11 from from IN cord-015569-vy49r1zd 526 12 one one CD cord-015569-vy49r1zd 526 13 another another DT cord-015569-vy49r1zd 526 14 and and CC cord-015569-vy49r1zd 526 15 the the DT cord-015569-vy49r1zd 526 16 tastes taste NNS cord-015569-vy49r1zd 526 17 of of IN cord-015569-vy49r1zd 526 18 caramel caramel JJ cord-015569-vy49r1zd 526 19 sauces sauce NNS cord-015569-vy49r1zd 526 20 prepared prepare VBN cord-015569-vy49r1zd 526 21 from from IN cord-015569-vy49r1zd 526 22 these these DT cord-015569-vy49r1zd 526 23 sugars sugar NNS cord-015569-vy49r1zd 526 24 were be VBD cord-015569-vy49r1zd 526 25 different different JJ cord-015569-vy49r1zd 526 26 . . . cord-015569-vy49r1zd 527 1 A a DT cord-015569-vy49r1zd 527 2 white white JJ cord-015569-vy49r1zd 527 3 coarse coarse RB cord-015569-vy49r1zd 527 4 bright bright JJ cord-015569-vy49r1zd 527 5 sugar sugar NN cord-015569-vy49r1zd 527 6 with with IN cord-015569-vy49r1zd 527 7 larger large JJR cord-015569-vy49r1zd 527 8 grain grain NN cord-015569-vy49r1zd 527 9 size size NN cord-015569-vy49r1zd 527 10 than than IN cord-015569-vy49r1zd 527 11 that that DT cord-015569-vy49r1zd 527 12 of of IN cord-015569-vy49r1zd 527 13 regular regular JJ cord-015569-vy49r1zd 527 14 granulated granulated JJ cord-015569-vy49r1zd 527 15 sugar sugar NN cord-015569-vy49r1zd 527 16 used use VBN cord-015569-vy49r1zd 527 17 as as IN cord-015569-vy49r1zd 527 18 an an DT cord-015569-vy49r1zd 527 19 experimental experimental JJ cord-015569-vy49r1zd 527 20 sucrose sucrose NN cord-015569-vy49r1zd 527 21 crystal crystal NN cord-015569-vy49r1zd 527 22 was be VBD cord-015569-vy49r1zd 527 23 milled mill VBN cord-015569-vy49r1zd 527 24 into into IN cord-015569-vy49r1zd 527 25 powder powder NN cord-015569-vy49r1zd 527 26 . . . cord-015569-vy49r1zd 528 1 In in IN cord-015569-vy49r1zd 528 2 a a DT cord-015569-vy49r1zd 528 3 differential differential JJ cord-015569-vy49r1zd 528 4 scanning scanning NN cord-015569-vy49r1zd 528 5 calorimetry calorimetry NN cord-015569-vy49r1zd 528 6 of of IN cord-015569-vy49r1zd 528 7 the the DT cord-015569-vy49r1zd 528 8 crystals crystal NNS cord-015569-vy49r1zd 528 9 , , , cord-015569-vy49r1zd 528 10 a a DT cord-015569-vy49r1zd 528 11 higher high JJR cord-015569-vy49r1zd 528 12 peak peak NN cord-015569-vy49r1zd 528 13 in in IN cord-015569-vy49r1zd 528 14 the the DT cord-015569-vy49r1zd 528 15 curve curve NN cord-015569-vy49r1zd 528 16 of of IN cord-015569-vy49r1zd 528 17 endothermic endothermic JJ cord-015569-vy49r1zd 528 18 heat heat NN cord-015569-vy49r1zd 528 19 flow flow NN cord-015569-vy49r1zd 528 20 shifted shift VBD cord-015569-vy49r1zd 528 21 to to IN cord-015569-vy49r1zd 528 22 higher high JJR cord-015569-vy49r1zd 528 23 temperature temperature NN cord-015569-vy49r1zd 528 24 side side NN cord-015569-vy49r1zd 528 25 after after IN cord-015569-vy49r1zd 528 26 milling mill VBG cord-015569-vy49r1zd 528 27 . . . cord-015569-vy49r1zd 529 1 The the DT cord-015569-vy49r1zd 529 2 powder powder NN cord-015569-vy49r1zd 529 3 crystal crystal NN cord-015569-vy49r1zd 529 4 became become VBD cord-015569-vy49r1zd 529 5 more more RBR cord-015569-vy49r1zd 529 6 stabilized stabilize VBN cord-015569-vy49r1zd 529 7 on on IN cord-015569-vy49r1zd 529 8 heating heating NN cord-015569-vy49r1zd 529 9 than than IN cord-015569-vy49r1zd 529 10 the the DT cord-015569-vy49r1zd 529 11 coarse coarse JJ cord-015569-vy49r1zd 529 12 crystal crystal NN cord-015569-vy49r1zd 529 13 . . . cord-015569-vy49r1zd 530 1 Using use VBG cord-015569-vy49r1zd 530 2 the the DT cord-015569-vy49r1zd 530 3 coarse coarse NN cord-015569-vy49r1zd 530 4 and and CC cord-015569-vy49r1zd 530 5 the the DT cord-015569-vy49r1zd 530 6 powder powder NN cord-015569-vy49r1zd 530 7 crystals crystal NNS cord-015569-vy49r1zd 530 8 , , , cord-015569-vy49r1zd 530 9 caramel caramel JJ cord-015569-vy49r1zd 530 10 sauces sauce NNS cord-015569-vy49r1zd 530 11 ( ( -LRB- cord-015569-vy49r1zd 530 12 ' ' `` cord-015569-vy49r1zd 530 13 ' ' `` cord-015569-vy49r1zd 530 14 sauce sauce NN cord-015569-vy49r1zd 530 15 C c NN cord-015569-vy49r1zd 530 16 ' ' '' cord-015569-vy49r1zd 530 17 ' ' '' cord-015569-vy49r1zd 530 18 and and CC cord-015569-vy49r1zd 530 19 ' ' '' cord-015569-vy49r1zd 530 20 ' ' '' cord-015569-vy49r1zd 530 21 sauce sauce NN cord-015569-vy49r1zd 530 22 P p NN cord-015569-vy49r1zd 530 23 ' ' '' cord-015569-vy49r1zd 530 24 ' ' '' cord-015569-vy49r1zd 530 25 , , , cord-015569-vy49r1zd 530 26 respectively respectively RB cord-015569-vy49r1zd 530 27 ) ) -RRB- cord-015569-vy49r1zd 530 28 were be VBD cord-015569-vy49r1zd 530 29 prepared prepare VBN cord-015569-vy49r1zd 530 30 . . . cord-015569-vy49r1zd 531 1 Sensory sensory JJ cord-015569-vy49r1zd 531 2 tests test NNS cord-015569-vy49r1zd 531 3 showed show VBD cord-015569-vy49r1zd 531 4 that that IN cord-015569-vy49r1zd 531 5 sauce sauce NN cord-015569-vy49r1zd 531 6 C c NN cord-015569-vy49r1zd 531 7 was be VBD cord-015569-vy49r1zd 531 8 more more RBR cord-015569-vy49r1zd 531 9 brownish brownish JJ cord-015569-vy49r1zd 531 10 in in IN cord-015569-vy49r1zd 531 11 color color NN cord-015569-vy49r1zd 531 12 and and CC cord-015569-vy49r1zd 531 13 was be VBD cord-015569-vy49r1zd 531 14 stronger strong JJR cord-015569-vy49r1zd 531 15 in in IN cord-015569-vy49r1zd 531 16 sourness sourness NN cord-015569-vy49r1zd 531 17 , , , cord-015569-vy49r1zd 531 18 bitterness bitterness NN cord-015569-vy49r1zd 531 19 and and CC cord-015569-vy49r1zd 531 20 acridity acridity NN cord-015569-vy49r1zd 531 21 . . . cord-015569-vy49r1zd 532 1 On on IN cord-015569-vy49r1zd 532 2 the the DT cord-015569-vy49r1zd 532 3 other other JJ cord-015569-vy49r1zd 532 4 hand hand NN cord-015569-vy49r1zd 532 5 , , , cord-015569-vy49r1zd 532 6 sauce sauce NN cord-015569-vy49r1zd 532 7 P p NN cord-015569-vy49r1zd 532 8 was be VBD cord-015569-vy49r1zd 532 9 better well JJR cord-015569-vy49r1zd 532 10 in in IN cord-015569-vy49r1zd 532 11 aroma aroma NN cord-015569-vy49r1zd 532 12 , , , cord-015569-vy49r1zd 532 13 stronger strong JJR cord-015569-vy49r1zd 532 14 in in IN cord-015569-vy49r1zd 532 15 sweetness sweetness NN cord-015569-vy49r1zd 532 16 and and CC cord-015569-vy49r1zd 532 17 more more RBR cord-015569-vy49r1zd 532 18 preferable preferable JJ cord-015569-vy49r1zd 532 19 in in IN cord-015569-vy49r1zd 532 20 taste taste NN cord-015569-vy49r1zd 532 21 and and CC cord-015569-vy49r1zd 532 22 aftertaste aftertaste NN cord-015569-vy49r1zd 532 23 . . . cord-015569-vy49r1zd 533 1 Sauce Sauce NNP cord-015569-vy49r1zd 533 2 C C NNP cord-015569-vy49r1zd 533 3 was be VBD cord-015569-vy49r1zd 533 4 lower low JJR cord-015569-vy49r1zd 533 5 in in IN cord-015569-vy49r1zd 533 6 pH pH NNP cord-015569-vy49r1zd 533 7 , , , cord-015569-vy49r1zd 533 8 giving give VBG cord-015569-vy49r1zd 533 9 stronger strong JJR cord-015569-vy49r1zd 533 10 sourness sourness NN cord-015569-vy49r1zd 533 11 . . . cord-015569-vy49r1zd 534 1 The the DT cord-015569-vy49r1zd 534 2 use use NN cord-015569-vy49r1zd 534 3 of of IN cord-015569-vy49r1zd 534 4 a a DT cord-015569-vy49r1zd 534 5 color color NN cord-015569-vy49r1zd 534 6 difference difference NN cord-015569-vy49r1zd 534 7 meter meter NN cord-015569-vy49r1zd 534 8 showed show VBD cord-015569-vy49r1zd 534 9 a a DT cord-015569-vy49r1zd 534 10 large large JJ cord-015569-vy49r1zd 534 11 difference difference NN cord-015569-vy49r1zd 534 12 between between IN cord-015569-vy49r1zd 534 13 the the DT cord-015569-vy49r1zd 534 14 two two CD cord-015569-vy49r1zd 534 15 sauces sauce NNS cord-015569-vy49r1zd 534 16 ( ( -LRB- cord-015569-vy49r1zd 534 17 DE=6.4 DE=6.4 NNP cord-015569-vy49r1zd 534 18 ) ) -RRB- cord-015569-vy49r1zd 534 19 . . . cord-015569-vy49r1zd 535 1 Coarse coarse JJ cord-015569-vy49r1zd 535 2 crystal crystal NN cord-015569-vy49r1zd 535 3 was be VBD cord-015569-vy49r1zd 535 4 less less RBR cord-015569-vy49r1zd 535 5 stable stable JJ cord-015569-vy49r1zd 535 6 on on IN cord-015569-vy49r1zd 535 7 heating heating NN cord-015569-vy49r1zd 535 8 and and CC cord-015569-vy49r1zd 535 9 sauce sauce NN cord-015569-vy49r1zd 535 10 C C NNP cord-015569-vy49r1zd 535 11 was be VBD cord-015569-vy49r1zd 535 12 more more RBR cord-015569-vy49r1zd 535 13 brownish brownish JJ cord-015569-vy49r1zd 535 14 in in IN cord-015569-vy49r1zd 535 15 color color NN cord-015569-vy49r1zd 535 16 , , , cord-015569-vy49r1zd 535 17 having have VBG cord-015569-vy49r1zd 535 18 stronger strong JJR cord-015569-vy49r1zd 535 19 bitterness bitterness NN cord-015569-vy49r1zd 535 20 . . . cord-015569-vy49r1zd 536 1 In in IN cord-015569-vy49r1zd 536 2 the the DT cord-015569-vy49r1zd 536 3 sensory sensory JJ cord-015569-vy49r1zd 536 4 studies study NNS cord-015569-vy49r1zd 536 5 for for IN cord-015569-vy49r1zd 536 6 flavor flavor NN cord-015569-vy49r1zd 536 7 development development NN cord-015569-vy49r1zd 536 8 , , , cord-015569-vy49r1zd 536 9 commercial commercial JJ cord-015569-vy49r1zd 536 10 products product NNS cord-015569-vy49r1zd 536 11 or or CC cord-015569-vy49r1zd 536 12 trial trial NN cord-015569-vy49r1zd 536 13 products product NNS cord-015569-vy49r1zd 536 14 are be VBP cord-015569-vy49r1zd 536 15 often often RB cord-015569-vy49r1zd 536 16 used use VBN cord-015569-vy49r1zd 536 17 as as IN cord-015569-vy49r1zd 536 18 samples sample NNS cord-015569-vy49r1zd 536 19 , , , cord-015569-vy49r1zd 536 20 because because IN cord-015569-vy49r1zd 536 21 sensory sensory JJ cord-015569-vy49r1zd 536 22 evaluation evaluation NN cord-015569-vy49r1zd 536 23 is be VBZ cord-015569-vy49r1zd 536 24 conducted conduct VBN cord-015569-vy49r1zd 536 25 considering consider VBG cord-015569-vy49r1zd 536 26 usual usual JJ cord-015569-vy49r1zd 536 27 behavior behavior NN cord-015569-vy49r1zd 536 28 of of IN cord-015569-vy49r1zd 536 29 eating eat VBG cord-015569-vy49r1zd 536 30 habit habit NN cord-015569-vy49r1zd 536 31 . . . cord-015569-vy49r1zd 537 1 But but CC cord-015569-vy49r1zd 537 2 in in IN cord-015569-vy49r1zd 537 3 the the DT cord-015569-vy49r1zd 537 4 case case NN cord-015569-vy49r1zd 537 5 of of IN cord-015569-vy49r1zd 537 6 odor odor NN cord-015569-vy49r1zd 537 7 - - HYPH cord-015569-vy49r1zd 537 8 taste taste NN cord-015569-vy49r1zd 537 9 interaction interaction NN cord-015569-vy49r1zd 537 10 studies study NNS cord-015569-vy49r1zd 537 11 , , , cord-015569-vy49r1zd 537 12 it -PRON- PRP cord-015569-vy49r1zd 537 13 is be VBZ cord-015569-vy49r1zd 537 14 desired desire VBN cord-015569-vy49r1zd 537 15 that that IN cord-015569-vy49r1zd 537 16 odorants odorant NNS cord-015569-vy49r1zd 537 17 and and CC cord-015569-vy49r1zd 537 18 tastants tastant NNS cord-015569-vy49r1zd 537 19 are be VBP cord-015569-vy49r1zd 537 20 completely completely RB cord-015569-vy49r1zd 537 21 separated separate VBN cord-015569-vy49r1zd 537 22 and and CC cord-015569-vy49r1zd 537 23 presented present VBN cord-015569-vy49r1zd 537 24 to to IN cord-015569-vy49r1zd 537 25 subjects subject NNS cord-015569-vy49r1zd 537 26 simultaneously simultaneously RB cord-015569-vy49r1zd 537 27 . . . cord-015569-vy49r1zd 538 1 In in IN cord-015569-vy49r1zd 538 2 this this DT cord-015569-vy49r1zd 538 3 study study NN cord-015569-vy49r1zd 538 4 , , , cord-015569-vy49r1zd 538 5 we -PRON- PRP cord-015569-vy49r1zd 538 6 established establish VBD cord-015569-vy49r1zd 538 7 a a DT cord-015569-vy49r1zd 538 8 simple simple JJ cord-015569-vy49r1zd 538 9 and and CC cord-015569-vy49r1zd 538 10 effective effective JJ cord-015569-vy49r1zd 538 11 way way NN cord-015569-vy49r1zd 538 12 of of IN cord-015569-vy49r1zd 538 13 presenting present VBG cord-015569-vy49r1zd 538 14 odor odor NN cord-015569-vy49r1zd 538 15 and and CC cord-015569-vy49r1zd 538 16 taste taste NN cord-015569-vy49r1zd 538 17 stimuli stimulus NNS cord-015569-vy49r1zd 538 18 separately separately RB cord-015569-vy49r1zd 538 19 under under IN cord-015569-vy49r1zd 538 20 two two CD cord-015569-vy49r1zd 538 21 model model NN cord-015569-vy49r1zd 538 22 systems system NNS cord-015569-vy49r1zd 538 23 : : : cord-015569-vy49r1zd 538 24 beverage beverage NN cord-015569-vy49r1zd 538 25 and and CC cord-015569-vy49r1zd 538 26 soup soup NN cord-015569-vy49r1zd 538 27 . . . cord-015569-vy49r1zd 539 1 Experiment.1 Experiment.1 NNP cord-015569-vy49r1zd 539 2 : : : cord-015569-vy49r1zd 540 1 Evaluation evaluation NN cord-015569-vy49r1zd 540 2 of of IN cord-015569-vy49r1zd 540 3 sweet sweet JJ cord-015569-vy49r1zd 540 4 / / SYM cord-015569-vy49r1zd 540 5 sour sour JJ cord-015569-vy49r1zd 540 6 intensity intensity NN cord-015569-vy49r1zd 540 7 in in IN cord-015569-vy49r1zd 540 8 fruit fruit NN cord-015569-vy49r1zd 540 9 flavor flavor NN cord-015569-vy49r1zd 540 10 beverage beverage NN cord-015569-vy49r1zd 540 11 Firstly firstly RB cord-015569-vy49r1zd 540 12 , , , cord-015569-vy49r1zd 540 13 we -PRON- PRP cord-015569-vy49r1zd 540 14 prepared prepare VBD cord-015569-vy49r1zd 540 15 simple simple JJ cord-015569-vy49r1zd 540 16 equipment equipment NN cord-015569-vy49r1zd 540 17 comprising comprise VBG cord-015569-vy49r1zd 540 18 clear clear JJ cord-015569-vy49r1zd 540 19 plastic plastic NN cord-015569-vy49r1zd 540 20 cup cup NN cord-015569-vy49r1zd 540 21 with with IN cord-015569-vy49r1zd 540 22 scented scented JJ cord-015569-vy49r1zd 540 23 papers paper NNS cord-015569-vy49r1zd 540 24 attached attach VBN cord-015569-vy49r1zd 540 25 on on IN cord-015569-vy49r1zd 540 26 the the DT cord-015569-vy49r1zd 540 27 upper upper JJ cord-015569-vy49r1zd 540 28 inside inside JJ cord-015569-vy49r1zd 540 29 edge edge NN cord-015569-vy49r1zd 540 30 . . . cord-015569-vy49r1zd 541 1 The the DT cord-015569-vy49r1zd 541 2 use use NN cord-015569-vy49r1zd 541 3 of of IN cord-015569-vy49r1zd 541 4 non non JJ cord-015569-vy49r1zd 541 5 - - JJ cord-015569-vy49r1zd 541 6 flavored flavored JJ cord-015569-vy49r1zd 541 7 solution solution NN cord-015569-vy49r1zd 541 8 and and CC cord-015569-vy49r1zd 541 9 flavor flavor NN cord-015569-vy49r1zd 541 10 on on IN cord-015569-vy49r1zd 541 11 the the DT cord-015569-vy49r1zd 541 12 scented scented JJ cord-015569-vy49r1zd 541 13 papers paper NNS cord-015569-vy49r1zd 541 14 allow allow VBP cord-015569-vy49r1zd 541 15 subjects subject NNS cord-015569-vy49r1zd 541 16 to to TO cord-015569-vy49r1zd 541 17 evaluate evaluate VB cord-015569-vy49r1zd 541 18 beverage beverage NN cord-015569-vy49r1zd 541 19 . . . cord-015569-vy49r1zd 542 1 Sugar sugar NN cord-015569-vy49r1zd 542 2 - - HYPH cord-015569-vy49r1zd 542 3 acid acid NN cord-015569-vy49r1zd 542 4 water water NN cord-015569-vy49r1zd 542 5 solution solution NN cord-015569-vy49r1zd 542 6 was be VBD cord-015569-vy49r1zd 542 7 used use VBN cord-015569-vy49r1zd 542 8 as as IN cord-015569-vy49r1zd 542 9 taste taste NN cord-015569-vy49r1zd 542 10 stimulus stimulus NN cord-015569-vy49r1zd 542 11 and and CC cord-015569-vy49r1zd 542 12 , , , cord-015569-vy49r1zd 542 13 Lemon Lemon NNP cord-015569-vy49r1zd 542 14 and and CC cord-015569-vy49r1zd 542 15 Strawberry Strawberry NNP cord-015569-vy49r1zd 542 16 flavors flavor NNS cord-015569-vy49r1zd 542 17 were be VBD cord-015569-vy49r1zd 542 18 used use VBN cord-015569-vy49r1zd 542 19 as as IN cord-015569-vy49r1zd 542 20 odor odor NN cord-015569-vy49r1zd 542 21 stimuli stimulus NNS cord-015569-vy49r1zd 542 22 . . . cord-015569-vy49r1zd 543 1 Untrained untrained JJ cord-015569-vy49r1zd 543 2 panel panel NN cord-015569-vy49r1zd 543 3 ( ( -LRB- cord-015569-vy49r1zd 543 4 n n NN cord-015569-vy49r1zd 543 5 = = SYM cord-015569-vy49r1zd 543 6 45 45 CD cord-015569-vy49r1zd 543 7 ) ) -RRB- cord-015569-vy49r1zd 543 8 evaluated evaluate VBN cord-015569-vy49r1zd 543 9 intensity intensity NN cord-015569-vy49r1zd 543 10 of of IN cord-015569-vy49r1zd 543 11 sweet sweet JJ cord-015569-vy49r1zd 543 12 and and CC cord-015569-vy49r1zd 543 13 sour sour JJ cord-015569-vy49r1zd 543 14 characters character NNS cord-015569-vy49r1zd 543 15 . . . cord-015569-vy49r1zd 544 1 The the DT cord-015569-vy49r1zd 544 2 result result NN cord-015569-vy49r1zd 544 3 showed show VBD cord-015569-vy49r1zd 544 4 that that IN cord-015569-vy49r1zd 544 5 Lemon Lemon NNP cord-015569-vy49r1zd 544 6 flavor flavor NN cord-015569-vy49r1zd 544 7 enhanced enhance VBD cord-015569-vy49r1zd 544 8 sour sour JJ cord-015569-vy49r1zd 544 9 character character NN cord-015569-vy49r1zd 544 10 and and CC cord-015569-vy49r1zd 544 11 decreased decrease VBD cord-015569-vy49r1zd 544 12 sweet sweet JJ cord-015569-vy49r1zd 544 13 character character NN cord-015569-vy49r1zd 544 14 when when WRB cord-015569-vy49r1zd 544 15 compared compare VBN cord-015569-vy49r1zd 544 16 with with IN cord-015569-vy49r1zd 544 17 non non JJ cord-015569-vy49r1zd 544 18 - - JJ cord-015569-vy49r1zd 544 19 flavored flavored JJ cord-015569-vy49r1zd 544 20 condition condition NN cord-015569-vy49r1zd 544 21 . . . cord-015569-vy49r1zd 545 1 Experiment.2 experiment.2 UH cord-015569-vy49r1zd 545 2 : : : cord-015569-vy49r1zd 545 3 Evaluation evaluation NN cord-015569-vy49r1zd 545 4 for for IN cord-015569-vy49r1zd 545 5 savory savory JJ cord-015569-vy49r1zd 545 6 -citrus -citrus CD cord-015569-vy49r1zd 545 7 flavor flavor NN cord-015569-vy49r1zd 545 8 interaction interaction NN cord-015569-vy49r1zd 546 1 We -PRON- PRP cord-015569-vy49r1zd 546 2 prepared prepare VBD cord-015569-vy49r1zd 546 3 ordinary ordinary JJ cord-015569-vy49r1zd 546 4 soup soup NN cord-015569-vy49r1zd 546 5 solution solution NN cord-015569-vy49r1zd 546 6 as as IN cord-015569-vy49r1zd 546 7 taste taste NN cord-015569-vy49r1zd 546 8 stimulus stimulus NN cord-015569-vy49r1zd 546 9 , , , cord-015569-vy49r1zd 546 10 with with IN cord-015569-vy49r1zd 546 11 two two CD cord-015569-vy49r1zd 546 12 savory savory JJ cord-015569-vy49r1zd 546 13 flavor flavor NN cord-015569-vy49r1zd 546 14 ( ( -LRB- cord-015569-vy49r1zd 546 15 Chicken Chicken NNP cord-015569-vy49r1zd 546 16 and and CC cord-015569-vy49r1zd 546 17 Dried Dried NNP cord-015569-vy49r1zd 546 18 bonito bonito NNP cord-015569-vy49r1zd 546 19 ) ) -RRB- cord-015569-vy49r1zd 546 20 and and CC cord-015569-vy49r1zd 546 21 two two CD cord-015569-vy49r1zd 546 22 citrus citrus NN cord-015569-vy49r1zd 546 23 flavor flavor NN cord-015569-vy49r1zd 546 24 ( ( -LRB- cord-015569-vy49r1zd 546 25 Lemon Lemon NNP cord-015569-vy49r1zd 546 26 and and CC cord-015569-vy49r1zd 546 27 Yuzu Yuzu NNP cord-015569-vy49r1zd 546 28 ) ) -RRB- cord-015569-vy49r1zd 546 29 as as IN cord-015569-vy49r1zd 546 30 odor odor NN cord-015569-vy49r1zd 546 31 stimuli stimulus NNS cord-015569-vy49r1zd 546 32 . . . cord-015569-vy49r1zd 547 1 Untrained untrained JJ cord-015569-vy49r1zd 547 2 panel panel NN cord-015569-vy49r1zd 547 3 ( ( -LRB- cord-015569-vy49r1zd 547 4 n=66 n=66 NN cord-015569-vy49r1zd 547 5 ) ) -RRB- cord-015569-vy49r1zd 547 6 evaluated evaluate VBD cord-015569-vy49r1zd 547 7 6 6 CD cord-015569-vy49r1zd 547 8 characters character NNS cord-015569-vy49r1zd 547 9 ( ( -LRB- cord-015569-vy49r1zd 547 10 saltiness saltiness NN cord-015569-vy49r1zd 547 11 , , , cord-015569-vy49r1zd 547 12 umami umami NN cord-015569-vy49r1zd 547 13 , , , cord-015569-vy49r1zd 547 14 sourness sourness NN cord-015569-vy49r1zd 547 15 , , , cord-015569-vy49r1zd 547 16 mild mild JJ cord-015569-vy49r1zd 547 17 , , , cord-015569-vy49r1zd 547 18 fatty fatty JJ cord-015569-vy49r1zd 547 19 , , , cord-015569-vy49r1zd 547 20 animalic animalic JJ cord-015569-vy49r1zd 547 21 ) ) -RRB- cord-015569-vy49r1zd 547 22 . . . cord-015569-vy49r1zd 548 1 The the DT cord-015569-vy49r1zd 548 2 results result NNS cord-015569-vy49r1zd 548 3 showed show VBD cord-015569-vy49r1zd 548 4 flavor flavor NN cord-015569-vy49r1zd 548 5 influenced influence VBD cord-015569-vy49r1zd 548 6 taste taste NN cord-015569-vy49r1zd 548 7 intensity intensity NN cord-015569-vy49r1zd 548 8 as as IN cord-015569-vy49r1zd 548 9 is be VBZ cord-015569-vy49r1zd 548 10 the the DT cord-015569-vy49r1zd 548 11 case case NN cord-015569-vy49r1zd 548 12 in in IN cord-015569-vy49r1zd 548 13 experiment experiment NN cord-015569-vy49r1zd 548 14 1 1 CD cord-015569-vy49r1zd 548 15 . . . cord-015569-vy49r1zd 549 1 In in IN cord-015569-vy49r1zd 549 2 conclusion conclusion NN cord-015569-vy49r1zd 549 3 , , , cord-015569-vy49r1zd 549 4 we -PRON- PRP cord-015569-vy49r1zd 549 5 successfully successfully RB cord-015569-vy49r1zd 549 6 showed show VBD cord-015569-vy49r1zd 549 7 the the DT cord-015569-vy49r1zd 549 8 important important JJ cord-015569-vy49r1zd 549 9 effect effect NN cord-015569-vy49r1zd 549 10 of of IN cord-015569-vy49r1zd 549 11 odor odor NN cord-015569-vy49r1zd 549 12 on on IN cord-015569-vy49r1zd 549 13 taste taste NN cord-015569-vy49r1zd 549 14 perception perception NN cord-015569-vy49r1zd 549 15 by by IN cord-015569-vy49r1zd 549 16 using use VBG cord-015569-vy49r1zd 549 17 this this DT cord-015569-vy49r1zd 549 18 study study NN cord-015569-vy49r1zd 549 19 . . . cord-015569-vy49r1zd 550 1 # # $ cord-015569-vy49r1zd 550 2 50 50 CD cord-015569-vy49r1zd 550 3 Added add VBN cord-015569-vy49r1zd 550 4 flavorings flavoring NNS cord-015569-vy49r1zd 550 5 enhance enhance VBP cord-015569-vy49r1zd 550 6 salivary salivary JJ cord-015569-vy49r1zd 550 7 hemodynamic hemodynamic JJ cord-015569-vy49r1zd 550 8 responses response NNS cord-015569-vy49r1zd 550 9 to to IN cord-015569-vy49r1zd 550 10 tastes taste NNS cord-015569-vy49r1zd 550 11 detected detect VBN cord-015569-vy49r1zd 550 12 by by IN cord-015569-vy49r1zd 550 13 near near JJ cord-015569-vy49r1zd 550 14 - - HYPH cord-015569-vy49r1zd 550 15 infrared infrared JJ cord-015569-vy49r1zd 550 16 spectroscopy spectroscopy NN cord-015569-vy49r1zd 550 17 -Flavor -flavor NN cord-015569-vy49r1zd 550 18 creation creation NN cord-015569-vy49r1zd 550 19 using use VBG cord-015569-vy49r1zd 550 20 optical optical JJ cord-015569-vy49r1zd 550 21 imaging imaging NN cord-015569-vy49r1zd 550 22 - - HYPH cord-015569-vy49r1zd 550 23 Dried dry VBN cord-015569-vy49r1zd 550 24 - - HYPH cord-015569-vy49r1zd 550 25 bonito bonito FW cord-015569-vy49r1zd 550 26 ( ( -LRB- cord-015569-vy49r1zd 550 27 Katsuobushi Katsuobushi NNP cord-015569-vy49r1zd 550 28 ) ) -RRB- cord-015569-vy49r1zd 550 29 broth broth NN cord-015569-vy49r1zd 550 30 , , , cord-015569-vy49r1zd 550 31 an an DT cord-015569-vy49r1zd 550 32 important important JJ cord-015569-vy49r1zd 550 33 seasoning seasoning NN cord-015569-vy49r1zd 550 34 in in IN cord-015569-vy49r1zd 550 35 Japanese japanese JJ cord-015569-vy49r1zd 550 36 cuisine cuisine NN cord-015569-vy49r1zd 550 37 , , , cord-015569-vy49r1zd 550 38 has have VBZ cord-015569-vy49r1zd 550 39 long long RB cord-015569-vy49r1zd 550 40 been be VBN cord-015569-vy49r1zd 550 41 used use VBN cord-015569-vy49r1zd 550 42 to to TO cord-015569-vy49r1zd 550 43 reinforce reinforce VB cord-015569-vy49r1zd 550 44 the the DT cord-015569-vy49r1zd 550 45 flavor flavor NN cord-015569-vy49r1zd 550 46 of of IN cord-015569-vy49r1zd 550 47 appetitive appetitive JJ cord-015569-vy49r1zd 550 48 foods food NNS cord-015569-vy49r1zd 550 49 . . . cord-015569-vy49r1zd 551 1 Not not RB cord-015569-vy49r1zd 551 2 only only RB cord-015569-vy49r1zd 551 3 the the DT cord-015569-vy49r1zd 551 4 taste taste NN cord-015569-vy49r1zd 551 5 but but CC cord-015569-vy49r1zd 551 6 also also RB cord-015569-vy49r1zd 552 1 the the DT cord-015569-vy49r1zd 552 2 aroma aroma NN cord-015569-vy49r1zd 552 3 components component NNS cord-015569-vy49r1zd 552 4 of of IN cord-015569-vy49r1zd 552 5 the the DT cord-015569-vy49r1zd 552 6 broth broth NN cord-015569-vy49r1zd 552 7 contribute contribute VBP cord-015569-vy49r1zd 552 8 well well RB cord-015569-vy49r1zd 552 9 to to IN cord-015569-vy49r1zd 552 10 the the DT cord-015569-vy49r1zd 552 11 enhancement enhancement NN cord-015569-vy49r1zd 552 12 . . . cord-015569-vy49r1zd 553 1 To to TO cord-015569-vy49r1zd 553 2 elucidate elucidate VB cord-015569-vy49r1zd 553 3 the the DT cord-015569-vy49r1zd 553 4 effects effect NNS cord-015569-vy49r1zd 553 5 of of IN cord-015569-vy49r1zd 553 6 aroma aroma NN cord-015569-vy49r1zd 553 7 from from IN cord-015569-vy49r1zd 553 8 dried dry VBN cord-015569-vy49r1zd 553 9 - - HYPH cord-015569-vy49r1zd 553 10 bonito bonito FW cord-015569-vy49r1zd 553 11 on on IN cord-015569-vy49r1zd 553 12 broth broth NN cord-015569-vy49r1zd 553 13 tastes taste NNS cord-015569-vy49r1zd 553 14 caused cause VBN cord-015569-vy49r1zd 553 15 by by IN cord-015569-vy49r1zd 553 16 the the DT cord-015569-vy49r1zd 553 17 central central JJ cord-015569-vy49r1zd 553 18 integration integration NN cord-015569-vy49r1zd 553 19 of of IN cord-015569-vy49r1zd 553 20 flavor flavor NN cord-015569-vy49r1zd 553 21 , , , cord-015569-vy49r1zd 553 22 we -PRON- PRP cord-015569-vy49r1zd 553 23 performed perform VBD cord-015569-vy49r1zd 553 24 optical optical JJ cord-015569-vy49r1zd 553 25 imaging imaging NN cord-015569-vy49r1zd 553 26 of of IN cord-015569-vy49r1zd 553 27 salivary salivary JJ cord-015569-vy49r1zd 553 28 hemodynamic hemodynamic JJ cord-015569-vy49r1zd 553 29 responses response NNS cord-015569-vy49r1zd 553 30 using use VBG cord-015569-vy49r1zd 553 31 near near JJ cord-015569-vy49r1zd 553 32 - - HYPH cord-015569-vy49r1zd 553 33 infrared infrared JJ cord-015569-vy49r1zd 553 34 spectroscopy spectroscopy NN cord-015569-vy49r1zd 553 35 ( ( -LRB- cord-015569-vy49r1zd 553 36 NIRS NIRS NNP cord-015569-vy49r1zd 553 37 ) ) -RRB- cord-015569-vy49r1zd 553 38 . . . cord-015569-vy49r1zd 554 1 When when WRB cord-015569-vy49r1zd 554 2 hemodynamic hemodynamic JJ cord-015569-vy49r1zd 554 3 responses response NNS cord-015569-vy49r1zd 554 4 to to IN cord-015569-vy49r1zd 554 5 a a DT cord-015569-vy49r1zd 554 6 reconstituted reconstitute VBN cord-015569-vy49r1zd 554 7 dried dry VBN cord-015569-vy49r1zd 554 8 - - HYPH cord-015569-vy49r1zd 554 9 bonito bonito NN cord-015569-vy49r1zd 554 10 flavored flavor VBN cord-015569-vy49r1zd 554 11 broth broth NN cord-015569-vy49r1zd 554 12 were be VBD cord-015569-vy49r1zd 554 13 compared compare VBN cord-015569-vy49r1zd 554 14 to to IN cord-015569-vy49r1zd 554 15 those those DT cord-015569-vy49r1zd 554 16 of of IN cord-015569-vy49r1zd 554 17 odorless odorless JJ cord-015569-vy49r1zd 554 18 broth broth NN cord-015569-vy49r1zd 554 19 taste taste NN cord-015569-vy49r1zd 554 20 solutions solution NNS cord-015569-vy49r1zd 554 21 , , , cord-015569-vy49r1zd 554 22 the the DT cord-015569-vy49r1zd 554 23 flavored flavored JJ cord-015569-vy49r1zd 554 24 broth broth NN cord-015569-vy49r1zd 554 25 produced produce VBD cord-015569-vy49r1zd 554 26 a a DT cord-015569-vy49r1zd 554 27 significantly significantly RB cord-015569-vy49r1zd 554 28 larger large JJR cord-015569-vy49r1zd 554 29 response response NN cord-015569-vy49r1zd 554 30 than than IN cord-015569-vy49r1zd 554 31 the the DT cord-015569-vy49r1zd 554 32 odorless odorless JJ cord-015569-vy49r1zd 554 33 broth broth NN cord-015569-vy49r1zd 554 34 . . . cord-015569-vy49r1zd 555 1 This this DT cord-015569-vy49r1zd 555 2 was be VBD cord-015569-vy49r1zd 555 3 the the DT cord-015569-vy49r1zd 555 4 case case NN cord-015569-vy49r1zd 555 5 for for IN cord-015569-vy49r1zd 555 6 five five CD cord-015569-vy49r1zd 555 7 of of IN cord-015569-vy49r1zd 555 8 the the DT cord-015569-vy49r1zd 555 9 ten ten CD cord-015569-vy49r1zd 555 10 participants participant NNS cord-015569-vy49r1zd 555 11 , , , cord-015569-vy49r1zd 555 12 who who WP cord-015569-vy49r1zd 555 13 felt feel VBD cord-015569-vy49r1zd 555 14 that that IN cord-015569-vy49r1zd 555 15 the the DT cord-015569-vy49r1zd 555 16 combination combination NN cord-015569-vy49r1zd 555 17 of of IN cord-015569-vy49r1zd 555 18 the the DT cord-015569-vy49r1zd 555 19 aroma aroma NN cord-015569-vy49r1zd 555 20 with with IN cord-015569-vy49r1zd 555 21 the the DT cord-015569-vy49r1zd 555 22 tastes taste NNS cord-015569-vy49r1zd 555 23 was be VBD cord-015569-vy49r1zd 555 24 congruent congruent JJ cord-015569-vy49r1zd 555 25 . . . cord-015569-vy49r1zd 556 1 In in IN cord-015569-vy49r1zd 556 2 the the DT cord-015569-vy49r1zd 556 3 remaining remain VBG cord-015569-vy49r1zd 556 4 five five CD cord-015569-vy49r1zd 556 5 who who WP cord-015569-vy49r1zd 556 6 felt feel VBD cord-015569-vy49r1zd 556 7 the the DT cord-015569-vy49r1zd 556 8 combination combination NN cord-015569-vy49r1zd 556 9 incongruent incongruent JJ cord-015569-vy49r1zd 556 10 , , , cord-015569-vy49r1zd 556 11 the the DT cord-015569-vy49r1zd 556 12 flavored flavored JJ cord-015569-vy49r1zd 556 13 broth broth NN cord-015569-vy49r1zd 556 14 did do VBD cord-015569-vy49r1zd 556 15 not not RB cord-015569-vy49r1zd 556 16 cause cause VB cord-015569-vy49r1zd 556 17 the the DT cord-015569-vy49r1zd 556 18 enhancement enhancement NN cord-015569-vy49r1zd 556 19 of of IN cord-015569-vy49r1zd 556 20 responses response NNS cord-015569-vy49r1zd 556 21 . . . cord-015569-vy49r1zd 557 1 Moreover moreover RB cord-015569-vy49r1zd 557 2 , , , cord-015569-vy49r1zd 557 3 when when WRB cord-015569-vy49r1zd 557 4 ( ( -LRB- cord-015569-vy49r1zd 557 5 Z z NN cord-015569-vy49r1zd 557 6 , , , cord-015569-vy49r1zd 557 7 Z)-4,7-Tridecadienal z)-4,7-tridecadienal NN cord-015569-vy49r1zd 557 8 , , , cord-015569-vy49r1zd 557 9 one one CD cord-015569-vy49r1zd 557 10 of of IN cord-015569-vy49r1zd 557 11 the the DT cord-015569-vy49r1zd 557 12 most most RBS cord-015569-vy49r1zd 557 13 important important JJ cord-015569-vy49r1zd 557 14 key key JJ cord-015569-vy49r1zd 557 15 aroma aroma NN cord-015569-vy49r1zd 557 16 components component NNS cord-015569-vy49r1zd 557 17 of of IN cord-015569-vy49r1zd 557 18 dried dry VBN cord-015569-vy49r1zd 557 19 - - HYPH cord-015569-vy49r1zd 557 20 bonito bonito NN cord-015569-vy49r1zd 557 21 extracts extract NNS cord-015569-vy49r1zd 557 22 , , , cord-015569-vy49r1zd 557 23 was be VBD cord-015569-vy49r1zd 557 24 added add VBN cord-015569-vy49r1zd 557 25 to to IN cord-015569-vy49r1zd 557 26 the the DT cord-015569-vy49r1zd 557 27 flavoring flavoring NN cord-015569-vy49r1zd 557 28 , , , cord-015569-vy49r1zd 557 29 the the DT cord-015569-vy49r1zd 557 30 latter latter JJ cord-015569-vy49r1zd 557 31 five five CD cord-015569-vy49r1zd 557 32 as as RB cord-015569-vy49r1zd 557 33 well well RB cord-015569-vy49r1zd 557 34 as as IN cord-015569-vy49r1zd 557 35 the the DT cord-015569-vy49r1zd 557 36 former former JJ cord-015569-vy49r1zd 557 37 five five CD cord-015569-vy49r1zd 557 38 participants participant NNS cord-015569-vy49r1zd 557 39 came come VBD cord-015569-vy49r1zd 557 40 to to TO cord-015569-vy49r1zd 557 41 feel feel VB cord-015569-vy49r1zd 557 42 congruency congruency NN cord-015569-vy49r1zd 557 43 of of IN cord-015569-vy49r1zd 557 44 the the DT cord-015569-vy49r1zd 557 45 reconstructed reconstruct VBN cord-015569-vy49r1zd 557 46 aroma aroma NN cord-015569-vy49r1zd 557 47 with with IN cord-015569-vy49r1zd 557 48 broth broth NN cord-015569-vy49r1zd 557 49 tastes taste NNS cord-015569-vy49r1zd 557 50 . . . cord-015569-vy49r1zd 558 1 The the DT cord-015569-vy49r1zd 558 2 reconstruncted reconstruncted JJ cord-015569-vy49r1zd 558 3 flavored flavored JJ cord-015569-vy49r1zd 558 4 broth broth NN cord-015569-vy49r1zd 558 5 produced produce VBN cord-015569-vy49r1zd 558 6 significantly significantly RB cord-015569-vy49r1zd 558 7 larger large JJR cord-015569-vy49r1zd 558 8 hemodynamic hemodynamic JJ cord-015569-vy49r1zd 558 9 responses response NNS cord-015569-vy49r1zd 558 10 than than IN cord-015569-vy49r1zd 558 11 the the DT cord-015569-vy49r1zd 558 12 odorless odorless JJ cord-015569-vy49r1zd 558 13 broth broth NN cord-015569-vy49r1zd 558 14 in in IN cord-015569-vy49r1zd 558 15 both both DT cord-015569-vy49r1zd 558 16 participantsÕ participantsÕ NNP cord-015569-vy49r1zd 558 17 groups group NNS cord-015569-vy49r1zd 558 18 . . . cord-015569-vy49r1zd 559 1 Accordingly accordingly RB cord-015569-vy49r1zd 559 2 , , , cord-015569-vy49r1zd 559 3 there there EX cord-015569-vy49r1zd 559 4 is be VBZ cord-015569-vy49r1zd 559 5 a a DT cord-015569-vy49r1zd 559 6 positive positive JJ cord-015569-vy49r1zd 559 7 correlation correlation NN cord-015569-vy49r1zd 559 8 between between IN cord-015569-vy49r1zd 559 9 the the DT cord-015569-vy49r1zd 559 10 degree degree NN cord-015569-vy49r1zd 559 11 of of IN cord-015569-vy49r1zd 559 12 congruency congruency NN cord-015569-vy49r1zd 559 13 and and CC cord-015569-vy49r1zd 559 14 increase increase NN cord-015569-vy49r1zd 559 15 of of IN cord-015569-vy49r1zd 559 16 the the DT cord-015569-vy49r1zd 559 17 salivary salivary NN cord-015569-vy49r1zd 559 18 responses response NNS cord-015569-vy49r1zd 559 19 . . . cord-015569-vy49r1zd 560 1 These these DT cord-015569-vy49r1zd 560 2 results result NNS cord-015569-vy49r1zd 560 3 indicate indicate VBP cord-015569-vy49r1zd 560 4 that that IN cord-015569-vy49r1zd 560 5 NIRS NIRS NNP cord-015569-vy49r1zd 560 6 offers offer VBZ cord-015569-vy49r1zd 560 7 a a DT cord-015569-vy49r1zd 560 8 sensitive sensitive JJ cord-015569-vy49r1zd 560 9 method method NN cord-015569-vy49r1zd 560 10 to to TO cord-015569-vy49r1zd 560 11 detect detect VB cord-015569-vy49r1zd 560 12 the the DT cord-015569-vy49r1zd 560 13 effect effect NN cord-015569-vy49r1zd 560 14 of of IN cord-015569-vy49r1zd 560 15 flavoring flavor VBG cord-015569-vy49r1zd 560 16 on on IN cord-015569-vy49r1zd 560 17 the the DT cord-015569-vy49r1zd 560 18 taste taste NN cord-015569-vy49r1zd 560 19 - - HYPH cord-015569-vy49r1zd 560 20 related relate VBN cord-015569-vy49r1zd 560 21 salivary salivary JJ cord-015569-vy49r1zd 560 22 hemodynamic hemodynamic JJ cord-015569-vy49r1zd 560 23 responses response NNS cord-015569-vy49r1zd 560 24 , , , cord-015569-vy49r1zd 560 25 dependent dependent JJ cord-015569-vy49r1zd 560 26 on on IN cord-015569-vy49r1zd 560 27 the the DT cord-015569-vy49r1zd 560 28 perceptual perceptual JJ cord-015569-vy49r1zd 560 29 experience experience NN cord-015569-vy49r1zd 560 30 of of IN cord-015569-vy49r1zd 560 31 the the DT cord-015569-vy49r1zd 560 32 combination combination NN cord-015569-vy49r1zd 560 33 of of IN cord-015569-vy49r1zd 560 34 aromas aroma NNS cord-015569-vy49r1zd 560 35 and and CC cord-015569-vy49r1zd 560 36 tastes taste NNS cord-015569-vy49r1zd 560 37 . . . cord-015569-vy49r1zd 561 1 Minty minty JJ cord-015569-vy49r1zd 561 2 flavors flavor NNS cord-015569-vy49r1zd 561 3 are be VBP cord-015569-vy49r1zd 561 4 utilized utilize VBN cord-015569-vy49r1zd 561 5 in in IN cord-015569-vy49r1zd 561 6 foods food NNS cord-015569-vy49r1zd 561 7 , , , cord-015569-vy49r1zd 561 8 beverages beverage NNS cord-015569-vy49r1zd 561 9 , , , cord-015569-vy49r1zd 561 10 toothpastes toothpaste NNS cord-015569-vy49r1zd 561 11 and and CC cord-015569-vy49r1zd 561 12 tobacco tobacco NN cord-015569-vy49r1zd 561 13 . . . cord-015569-vy49r1zd 562 1 Minty minty JJ cord-015569-vy49r1zd 562 2 flavors flavor NNS cord-015569-vy49r1zd 562 3 are be VBP cord-015569-vy49r1zd 562 4 considered consider VBN cord-015569-vy49r1zd 562 5 to to TO cord-015569-vy49r1zd 562 6 have have VB cord-015569-vy49r1zd 562 7 a a DT cord-015569-vy49r1zd 562 8 relaxing relaxing JJ cord-015569-vy49r1zd 562 9 effect effect NN cord-015569-vy49r1zd 562 10 , , , cord-015569-vy49r1zd 562 11 which which WDT cord-015569-vy49r1zd 562 12 is be VBZ cord-015569-vy49r1zd 562 13 necessary necessary JJ cord-015569-vy49r1zd 562 14 for for IN cord-015569-vy49r1zd 562 15 us -PRON- PRP cord-015569-vy49r1zd 562 16 , , , cord-015569-vy49r1zd 562 17 living live VBG cord-015569-vy49r1zd 562 18 in in IN cord-015569-vy49r1zd 562 19 modern modern JJ cord-015569-vy49r1zd 562 20 and and CC cord-015569-vy49r1zd 562 21 urban urban JJ cord-015569-vy49r1zd 562 22 societies society NNS cord-015569-vy49r1zd 562 23 . . . cord-015569-vy49r1zd 563 1 The the DT cord-015569-vy49r1zd 563 2 authors author NNS cord-015569-vy49r1zd 563 3 have have VBP cord-015569-vy49r1zd 563 4 reported report VBN cord-015569-vy49r1zd 563 5 that that IN cord-015569-vy49r1zd 563 6 the the DT cord-015569-vy49r1zd 563 7 participants participant NNS cord-015569-vy49r1zd 563 8 evaluated evaluate VBD cord-015569-vy49r1zd 563 9 themselves -PRON- PRP cord-015569-vy49r1zd 563 10 more more RBR cord-015569-vy49r1zd 563 11 relaxing relaxing JJ cord-015569-vy49r1zd 563 12 after after IN cord-015569-vy49r1zd 563 13 smelling smell VBG cord-015569-vy49r1zd 563 14 minty minty JJ cord-015569-vy49r1zd 563 15 odor odor NN cord-015569-vy49r1zd 563 16 , , , cord-015569-vy49r1zd 563 17 when when WRB cord-015569-vy49r1zd 563 18 they -PRON- PRP cord-015569-vy49r1zd 563 19 were be VBD cord-015569-vy49r1zd 563 20 tied tie VBN cord-015569-vy49r1zd 563 21 out out RP cord-015569-vy49r1zd 563 22 for for IN cord-015569-vy49r1zd 563 23 solving solve VBG cord-015569-vy49r1zd 563 24 hard hard JJ cord-015569-vy49r1zd 563 25 puzzles puzzle NNS cord-015569-vy49r1zd 563 26 . . . cord-015569-vy49r1zd 564 1 However however RB cord-015569-vy49r1zd 564 2 , , , cord-015569-vy49r1zd 564 3 psychological psychological JJ cord-015569-vy49r1zd 564 4 and and CC cord-015569-vy49r1zd 564 5 physiological physiological JJ cord-015569-vy49r1zd 564 6 effects effect NNS cord-015569-vy49r1zd 564 7 of of IN cord-015569-vy49r1zd 564 8 minty minty JJ cord-015569-vy49r1zd 564 9 flavors flavor NNS cord-015569-vy49r1zd 564 10 are be VBP cord-015569-vy49r1zd 564 11 still still RB cord-015569-vy49r1zd 564 12 unclear unclear JJ cord-015569-vy49r1zd 564 13 . . . cord-015569-vy49r1zd 565 1 This this DT cord-015569-vy49r1zd 565 2 study study NN cord-015569-vy49r1zd 565 3 was be VBD cord-015569-vy49r1zd 565 4 aimed aim VBN cord-015569-vy49r1zd 565 5 to to TO cord-015569-vy49r1zd 565 6 reveal reveal VB cord-015569-vy49r1zd 565 7 brain brain NN cord-015569-vy49r1zd 565 8 responses response NNS cord-015569-vy49r1zd 565 9 to to IN cord-015569-vy49r1zd 565 10 minty minty JJ cord-015569-vy49r1zd 565 11 flavors flavor NNS cord-015569-vy49r1zd 565 12 and and CC cord-015569-vy49r1zd 565 13 minty minty JJ cord-015569-vy49r1zd 565 14 odors odor NNS cord-015569-vy49r1zd 565 15 with with IN cord-015569-vy49r1zd 565 16 NIRS NIRS NNP cord-015569-vy49r1zd 565 17 ( ( -LRB- cord-015569-vy49r1zd 565 18 near near IN cord-015569-vy49r1zd 565 19 infrared infrared JJ cord-015569-vy49r1zd 565 20 spectroscopy spectroscopy NN cord-015569-vy49r1zd 565 21 ) ) -RRB- cord-015569-vy49r1zd 565 22 . . . cord-015569-vy49r1zd 566 1 Sixty sixty CD cord-015569-vy49r1zd 566 2 female female JJ cord-015569-vy49r1zd 566 3 university university NN cord-015569-vy49r1zd 566 4 students student NNS cord-015569-vy49r1zd 566 5 participated participate VBD cord-015569-vy49r1zd 566 6 in in IN cord-015569-vy49r1zd 566 7 this this DT cord-015569-vy49r1zd 566 8 study study NN cord-015569-vy49r1zd 566 9 . . . cord-015569-vy49r1zd 567 1 They -PRON- PRP cord-015569-vy49r1zd 567 2 received receive VBD cord-015569-vy49r1zd 567 3 detailed detailed JJ cord-015569-vy49r1zd 567 4 explanation explanation NN cord-015569-vy49r1zd 567 5 about about IN cord-015569-vy49r1zd 567 6 the the DT cord-015569-vy49r1zd 567 7 experiment experiment NN cord-015569-vy49r1zd 567 8 and and CC cord-015569-vy49r1zd 567 9 wrote write VBD cord-015569-vy49r1zd 567 10 consent consent NN cord-015569-vy49r1zd 567 11 for for IN cord-015569-vy49r1zd 567 12 participating participate VBG cord-015569-vy49r1zd 567 13 in in IN cord-015569-vy49r1zd 567 14 this this DT cord-015569-vy49r1zd 567 15 study study NN cord-015569-vy49r1zd 567 16 . . . cord-015569-vy49r1zd 568 1 The the DT cord-015569-vy49r1zd 568 2 three three CD cord-015569-vy49r1zd 568 3 minty minty JJ cord-015569-vy49r1zd 568 4 stimuli stimulus NNS cord-015569-vy49r1zd 568 5 , , , cord-015569-vy49r1zd 568 6 menthol menthol NN cord-015569-vy49r1zd 568 7 , , , cord-015569-vy49r1zd 568 8 spearmint spearmint NN cord-015569-vy49r1zd 568 9 and and CC cord-015569-vy49r1zd 568 10 peppermint peppermint NN cord-015569-vy49r1zd 568 11 and and CC cord-015569-vy49r1zd 568 12 the the DT cord-015569-vy49r1zd 568 13 other other JJ cord-015569-vy49r1zd 568 14 three three CD cord-015569-vy49r1zd 568 15 odor odor NN cord-015569-vy49r1zd 568 16 stimuli stimulus NNS cord-015569-vy49r1zd 568 17 , , , cord-015569-vy49r1zd 568 18 rose rise VBD cord-015569-vy49r1zd 568 19 , , , cord-015569-vy49r1zd 568 20 skatol skatol NNP cord-015569-vy49r1zd 568 21 and and CC cord-015569-vy49r1zd 568 22 orange orange NNP cord-015569-vy49r1zd 568 23 , , , cord-015569-vy49r1zd 568 24 were be VBD cord-015569-vy49r1zd 568 25 administered administer VBN cord-015569-vy49r1zd 568 26 to to IN cord-015569-vy49r1zd 568 27 the the DT cord-015569-vy49r1zd 568 28 participants participant NNS cord-015569-vy49r1zd 568 29 via via IN cord-015569-vy49r1zd 568 30 the the DT cord-015569-vy49r1zd 568 31 olfactometer olfactometer NN cord-015569-vy49r1zd 568 32 . . . cord-015569-vy49r1zd 569 1 The the DT cord-015569-vy49r1zd 569 2 participants participant NNS cord-015569-vy49r1zd 569 3 were be VBD cord-015569-vy49r1zd 569 4 asked ask VBN cord-015569-vy49r1zd 569 5 to to TO cord-015569-vy49r1zd 569 6 smell smell VB cord-015569-vy49r1zd 569 7 the the DT cord-015569-vy49r1zd 569 8 stimuli stimulus NNS cord-015569-vy49r1zd 569 9 by by IN cord-015569-vy49r1zd 569 10 an an DT cord-015569-vy49r1zd 569 11 orthonasal orthonasal NN cord-015569-vy49r1zd 569 12 or or CC cord-015569-vy49r1zd 569 13 retronasal retronasal NN cord-015569-vy49r1zd 569 14 route route NN cord-015569-vy49r1zd 569 15 or or CC cord-015569-vy49r1zd 569 16 to to TO cord-015569-vy49r1zd 569 17 taste taste VB cord-015569-vy49r1zd 569 18 them -PRON- PRP cord-015569-vy49r1zd 569 19 . . . cord-015569-vy49r1zd 570 1 Brain brain NN cord-015569-vy49r1zd 570 2 responses response NNS cord-015569-vy49r1zd 570 3 were be VBD cord-015569-vy49r1zd 570 4 measured measure VBN cord-015569-vy49r1zd 570 5 with with IN cord-015569-vy49r1zd 570 6 NIRS NIRS NNP cord-015569-vy49r1zd 570 7 ( ( -LRB- cord-015569-vy49r1zd 570 8 BOM-1 BOM-1 NNP cord-015569-vy49r1zd 570 9 , , , cord-015569-vy49r1zd 570 10 Omegawave Omegawave NNP cord-015569-vy49r1zd 570 11 , , , cord-015569-vy49r1zd 570 12 CO CO NNP cord-015569-vy49r1zd 570 13 LTD LTD NNP cord-015569-vy49r1zd 570 14 ) ) -RRB- cord-015569-vy49r1zd 570 15 and and CC cord-015569-vy49r1zd 570 16 recorded record VBN cord-015569-vy49r1zd 570 17 with with IN cord-015569-vy49r1zd 570 18 AD ad NN cord-015569-vy49r1zd 570 19 converter converter NN cord-015569-vy49r1zd 570 20 ( ( -LRB- cord-015569-vy49r1zd 570 21 Powerlab powerlab NN cord-015569-vy49r1zd 570 22 ) ) -RRB- cord-015569-vy49r1zd 570 23 connected connect VBN cord-015569-vy49r1zd 570 24 to to IN cord-015569-vy49r1zd 570 25 the the DT cord-015569-vy49r1zd 570 26 iMac iMac NNP cord-015569-vy49r1zd 570 27 . . . cord-015569-vy49r1zd 571 1 The the DT cord-015569-vy49r1zd 571 2 participants participant NNS cord-015569-vy49r1zd 571 3 were be VBD cord-015569-vy49r1zd 571 4 also also RB cord-015569-vy49r1zd 571 5 asked ask VBN cord-015569-vy49r1zd 571 6 to to TO cord-015569-vy49r1zd 571 7 evaluate evaluate VB cord-015569-vy49r1zd 571 8 the the DT cord-015569-vy49r1zd 571 9 intensity intensity NN cord-015569-vy49r1zd 571 10 of of IN cord-015569-vy49r1zd 571 11 the the DT cord-015569-vy49r1zd 571 12 odor odor NN cord-015569-vy49r1zd 571 13 continuously continuously RB cord-015569-vy49r1zd 571 14 with with IN cord-015569-vy49r1zd 571 15 the the DT cord-015569-vy49r1zd 571 16 apparatus apparatus NN cord-015569-vy49r1zd 571 17 which which WDT cord-015569-vy49r1zd 571 18 outputs output VBZ cord-015569-vy49r1zd 571 19 0;5 0;5 CD cord-015569-vy49r1zd 572 1 V v LS cord-015569-vy49r1zd 572 2 being be VBG cord-015569-vy49r1zd 572 3 based base VBN cord-015569-vy49r1zd 572 4 on on IN cord-015569-vy49r1zd 572 5 the the DT cord-015569-vy49r1zd 572 6 participantsÕ participantsÕ NNP cord-015569-vy49r1zd 572 7 evaluations evaluation NNS cord-015569-vy49r1zd 572 8 . . . cord-015569-vy49r1zd 573 1 The the DT cord-015569-vy49r1zd 573 2 results result NNS cord-015569-vy49r1zd 573 3 showed show VBD cord-015569-vy49r1zd 573 4 that that IN cord-015569-vy49r1zd 573 5 the the DT cord-015569-vy49r1zd 573 6 stimuli stimulus NNS cord-015569-vy49r1zd 573 7 were be VBD cord-015569-vy49r1zd 573 8 recognized recognize VBN cord-015569-vy49r1zd 573 9 faster fast RBR cord-015569-vy49r1zd 573 10 and and CC cord-015569-vy49r1zd 573 11 stronger strong JJR cord-015569-vy49r1zd 573 12 when when WRB cord-015569-vy49r1zd 573 13 the the DT cord-015569-vy49r1zd 573 14 stimuli stimulus NNS cord-015569-vy49r1zd 573 15 were be VBD cord-015569-vy49r1zd 573 16 administrated administrate VBN cord-015569-vy49r1zd 573 17 via via IN cord-015569-vy49r1zd 573 18 orthonasal orthonasal NN cord-015569-vy49r1zd 573 19 and and CC cord-015569-vy49r1zd 573 20 retronasal retronasal NN cord-015569-vy49r1zd 573 21 routes route NNS cord-015569-vy49r1zd 573 22 than than IN cord-015569-vy49r1zd 573 23 via via IN cord-015569-vy49r1zd 573 24 oral oral JJ cord-015569-vy49r1zd 573 25 cavity cavity NN cord-015569-vy49r1zd 573 26 . . . cord-015569-vy49r1zd 574 1 The the DT cord-015569-vy49r1zd 574 2 rose rose JJ cord-015569-vy49r1zd 574 3 odor odor NN cord-015569-vy49r1zd 574 4 and and CC cord-015569-vy49r1zd 574 5 orange orange JJ cord-015569-vy49r1zd 574 6 odor odor NN cord-015569-vy49r1zd 574 7 were be VBD cord-015569-vy49r1zd 574 8 recognized recognize VBN cord-015569-vy49r1zd 574 9 faster fast RBR cord-015569-vy49r1zd 574 10 and and CC cord-015569-vy49r1zd 574 11 stronger strong JJR cord-015569-vy49r1zd 574 12 than than IN cord-015569-vy49r1zd 574 13 the the DT cord-015569-vy49r1zd 574 14 menthol menthol NN cord-015569-vy49r1zd 574 15 odor odor NN cord-015569-vy49r1zd 574 16 . . . cord-015569-vy49r1zd 575 1 The the DT cord-015569-vy49r1zd 575 2 right right JJ cord-015569-vy49r1zd 575 3 forebrain forebrain NN cord-015569-vy49r1zd 575 4 showed show VBD cord-015569-vy49r1zd 575 5 greater great JJR cord-015569-vy49r1zd 575 6 responses response NNS cord-015569-vy49r1zd 575 7 to to IN cord-015569-vy49r1zd 575 8 the the DT cord-015569-vy49r1zd 575 9 stimuli stimulus NNS cord-015569-vy49r1zd 575 10 via via IN cord-015569-vy49r1zd 575 11 an an DT cord-015569-vy49r1zd 575 12 orthonasal orthonasal NN cord-015569-vy49r1zd 575 13 route route NN cord-015569-vy49r1zd 575 14 than than IN cord-015569-vy49r1zd 575 15 via via IN cord-015569-vy49r1zd 575 16 the the DT cord-015569-vy49r1zd 575 17 other other JJ cord-015569-vy49r1zd 575 18 routes route NNS cord-015569-vy49r1zd 575 19 , , , cord-015569-vy49r1zd 575 20 and and CC cord-015569-vy49r1zd 575 21 greater great JJR cord-015569-vy49r1zd 575 22 responses response NNS cord-015569-vy49r1zd 575 23 to to IN cord-015569-vy49r1zd 575 24 the the DT cord-015569-vy49r1zd 575 25 rose rose JJ cord-015569-vy49r1zd 575 26 odor odor NN cord-015569-vy49r1zd 575 27 than than IN cord-015569-vy49r1zd 575 28 the the DT cord-015569-vy49r1zd 575 29 menthol menthol NN cord-015569-vy49r1zd 575 30 and and CC cord-015569-vy49r1zd 575 31 the the DT cord-015569-vy49r1zd 575 32 peppermint peppermint NN cord-015569-vy49r1zd 575 33 odors odor NNS cord-015569-vy49r1zd 575 34 . . . cord-015569-vy49r1zd 576 1 Currently currently RB cord-015569-vy49r1zd 576 2 existing exist VBG cord-015569-vy49r1zd 576 3 odorant odorant NN cord-015569-vy49r1zd 576 4 sensors sensor NNS cord-015569-vy49r1zd 576 5 are be VBP cord-015569-vy49r1zd 576 6 mainly mainly RB cord-015569-vy49r1zd 576 7 fabricated fabricate VBN cord-015569-vy49r1zd 576 8 based base VBN cord-015569-vy49r1zd 576 9 on on IN cord-015569-vy49r1zd 576 10 metal metal NN cord-015569-vy49r1zd 576 11 - - HYPH cord-015569-vy49r1zd 576 12 oxide oxide NN cord-015569-vy49r1zd 576 13 semiconductor semiconductor NN cord-015569-vy49r1zd 576 14 devices device NNS cord-015569-vy49r1zd 576 15 , , , cord-015569-vy49r1zd 576 16 conducting conduct VBG cord-015569-vy49r1zd 576 17 polymers polymer NNS cord-015569-vy49r1zd 576 18 , , , cord-015569-vy49r1zd 576 19 quartz quartz NNP cord-015569-vy49r1zd 576 20 crystal crystal NNP cord-015569-vy49r1zd 576 21 microbalances microbalance NNS cord-015569-vy49r1zd 576 22 , , , cord-015569-vy49r1zd 576 23 or or CC cord-015569-vy49r1zd 576 24 surface surface NN cord-015569-vy49r1zd 576 25 acoustic acoustic JJ cord-015569-vy49r1zd 576 26 wave wave NN cord-015569-vy49r1zd 576 27 detectors detector NNS cord-015569-vy49r1zd 576 28 . . . cord-015569-vy49r1zd 577 1 These these DT cord-015569-vy49r1zd 577 2 sensors sensor NNS cord-015569-vy49r1zd 577 3 have have VBP cord-015569-vy49r1zd 577 4 been be VBN cord-015569-vy49r1zd 577 5 studied study VBN cord-015569-vy49r1zd 577 6 for for IN cord-015569-vy49r1zd 577 7 improving improve VBG cord-015569-vy49r1zd 577 8 on on IN cord-015569-vy49r1zd 577 9 various various JJ cord-015569-vy49r1zd 577 10 parameters parameter NNS cord-015569-vy49r1zd 577 11 , , , cord-015569-vy49r1zd 577 12 such such JJ cord-015569-vy49r1zd 577 13 as as IN cord-015569-vy49r1zd 577 14 sensitivity sensitivity NN cord-015569-vy49r1zd 577 15 , , , cord-015569-vy49r1zd 577 16 selectivity selectivity NN cord-015569-vy49r1zd 577 17 , , , cord-015569-vy49r1zd 577 18 response response NN cord-015569-vy49r1zd 577 19 speed speed NN cord-015569-vy49r1zd 577 20 , , , cord-015569-vy49r1zd 577 21 and and CC cord-015569-vy49r1zd 577 22 portability portability NN cord-015569-vy49r1zd 577 23 . . . cord-015569-vy49r1zd 578 1 However however RB cord-015569-vy49r1zd 578 2 , , , cord-015569-vy49r1zd 578 3 it -PRON- PRP cord-015569-vy49r1zd 578 4 has have VBZ cord-015569-vy49r1zd 578 5 been be VBN cord-015569-vy49r1zd 578 6 difficult difficult JJ cord-015569-vy49r1zd 578 7 to to TO cord-015569-vy49r1zd 578 8 develop develop VB cord-015569-vy49r1zd 578 9 odorant odorant NN cord-015569-vy49r1zd 578 10 sensor sensor NN cord-015569-vy49r1zd 578 11 elements element NNS cord-015569-vy49r1zd 578 12 that that WDT cord-015569-vy49r1zd 578 13 incorporate incorporate VBP cord-015569-vy49r1zd 578 14 a a DT cord-015569-vy49r1zd 578 15 combination combination NN cord-015569-vy49r1zd 578 16 of of IN cord-015569-vy49r1zd 578 17 desirable desirable JJ cord-015569-vy49r1zd 578 18 properties property NNS cord-015569-vy49r1zd 578 19 . . . cord-015569-vy49r1zd 579 1 In in IN cord-015569-vy49r1zd 579 2 contrast contrast NN cord-015569-vy49r1zd 579 3 , , , cord-015569-vy49r1zd 579 4 living live VBG cord-015569-vy49r1zd 579 5 organisms organism NNS cord-015569-vy49r1zd 579 6 , , , cord-015569-vy49r1zd 579 7 especially especially RB cord-015569-vy49r1zd 579 8 insects insect NNS cord-015569-vy49r1zd 579 9 , , , cord-015569-vy49r1zd 579 10 use use VBP cord-015569-vy49r1zd 579 11 numerous numerous JJ cord-015569-vy49r1zd 579 12 olfactory olfactory JJ cord-015569-vy49r1zd 579 13 sensory sensory JJ cord-015569-vy49r1zd 579 14 cells cell NNS cord-015569-vy49r1zd 579 15 , , , cord-015569-vy49r1zd 579 16 which which WDT cord-015569-vy49r1zd 579 17 express express VBP cord-015569-vy49r1zd 579 18 odorant odorant NN cord-015569-vy49r1zd 579 19 receptors receptor NNS cord-015569-vy49r1zd 579 20 , , , cord-015569-vy49r1zd 579 21 to to TO cord-015569-vy49r1zd 579 22 sensitively sensitively RB cord-015569-vy49r1zd 579 23 detect detect VB cord-015569-vy49r1zd 579 24 environmental environmental JJ cord-015569-vy49r1zd 579 25 odorants odorant NNS cord-015569-vy49r1zd 579 26 in in IN cord-015569-vy49r1zd 579 27 real real JJ cord-015569-vy49r1zd 579 28 time time NN cord-015569-vy49r1zd 579 29 . . . cord-015569-vy49r1zd 580 1 So so RB cord-015569-vy49r1zd 580 2 far far RB cord-015569-vy49r1zd 580 3 , , , cord-015569-vy49r1zd 580 4 we -PRON- PRP cord-015569-vy49r1zd 580 5 have have VBP cord-015569-vy49r1zd 580 6 developed develop VBN cord-015569-vy49r1zd 580 7 a a DT cord-015569-vy49r1zd 580 8 compact compact JJ cord-015569-vy49r1zd 580 9 odorant odorant NN cord-015569-vy49r1zd 580 10 sensor sensor NN cord-015569-vy49r1zd 580 11 that that WDT cord-015569-vy49r1zd 580 12 consists consist VBZ cord-015569-vy49r1zd 580 13 of of IN cord-015569-vy49r1zd 580 14 a a DT cord-015569-vy49r1zd 580 15 multichannel multichannel JJ cord-015569-vy49r1zd 580 16 fluidic fluidic JJ cord-015569-vy49r1zd 580 17 device device NN cord-015569-vy49r1zd 580 18 and and CC cord-015569-vy49r1zd 580 19 Xenopus Xenopus NNP cord-015569-vy49r1zd 580 20 laevis laevi NNS cord-015569-vy49r1zd 580 21 oocytes oocyte NNS cord-015569-vy49r1zd 580 22 expressing express VBG cord-015569-vy49r1zd 580 23 insect insect NN cord-015569-vy49r1zd 580 24 odorant odorant NN cord-015569-vy49r1zd 580 25 receptors receptor NNS cord-015569-vy49r1zd 580 26 . . . cord-015569-vy49r1zd 581 1 Although although IN cord-015569-vy49r1zd 581 2 this this DT cord-015569-vy49r1zd 581 3 odorant odorant NN cord-015569-vy49r1zd 581 4 sensor sensor NN cord-015569-vy49r1zd 581 5 possessed possess VBD cord-015569-vy49r1zd 581 6 fast fast JJ cord-015569-vy49r1zd 581 7 responsiveness responsiveness NN cord-015569-vy49r1zd 581 8 and and CC cord-015569-vy49r1zd 581 9 good good JJ cord-015569-vy49r1zd 581 10 portability portability NN cord-015569-vy49r1zd 581 11 , , , cord-015569-vy49r1zd 581 12 it -PRON- PRP cord-015569-vy49r1zd 581 13 had have VBD cord-015569-vy49r1zd 581 14 some some DT cord-015569-vy49r1zd 581 15 technical technical JJ cord-015569-vy49r1zd 581 16 disadvantages disadvantage NNS cord-015569-vy49r1zd 581 17 in in IN cord-015569-vy49r1zd 581 18 terms term NNS cord-015569-vy49r1zd 581 19 of of IN cord-015569-vy49r1zd 581 20 the the DT cord-015569-vy49r1zd 581 21 stability stability NN cord-015569-vy49r1zd 581 22 of of IN cord-015569-vy49r1zd 581 23 response response NN cord-015569-vy49r1zd 581 24 measurements measurement NNS cord-015569-vy49r1zd 581 25 in in IN cord-015569-vy49r1zd 581 26 the the DT cord-015569-vy49r1zd 581 27 oocytes oocyte NNS cord-015569-vy49r1zd 581 28 . . . cord-015569-vy49r1zd 582 1 Here here RB cord-015569-vy49r1zd 582 2 , , , cord-015569-vy49r1zd 582 3 we -PRON- PRP cord-015569-vy49r1zd 582 4 report report VBP cord-015569-vy49r1zd 582 5 the the DT cord-015569-vy49r1zd 582 6 development development NN cord-015569-vy49r1zd 582 7 of of IN cord-015569-vy49r1zd 582 8 new new JJ cord-015569-vy49r1zd 582 9 odorant odorant NN cord-015569-vy49r1zd 582 10 sensor sensor NN cord-015569-vy49r1zd 582 11 elements element NNS cord-015569-vy49r1zd 582 12 that that WDT cord-015569-vy49r1zd 582 13 enable enable VBP cord-015569-vy49r1zd 582 14 us -PRON- PRP cord-015569-vy49r1zd 582 15 to to TO cord-015569-vy49r1zd 582 16 acquire acquire VB cord-015569-vy49r1zd 582 17 stable stable JJ cord-015569-vy49r1zd 582 18 odorant odorant NN cord-015569-vy49r1zd 582 19 response response NN cord-015569-vy49r1zd 582 20 measurements measurement NNS cord-015569-vy49r1zd 582 21 . . . cord-015569-vy49r1zd 583 1 We -PRON- PRP cord-015569-vy49r1zd 583 2 introduced introduce VBD cord-015569-vy49r1zd 583 3 insect insect NN cord-015569-vy49r1zd 583 4 odorant odorant NN cord-015569-vy49r1zd 583 5 receptors receptor NNS cord-015569-vy49r1zd 583 6 and and CC cord-015569-vy49r1zd 583 7 the the DT cord-015569-vy49r1zd 583 8 olfactory olfactory JJ cord-015569-vy49r1zd 583 9 receptor receptor NN cord-015569-vy49r1zd 583 10 co co NN cord-015569-vy49r1zd 583 11 - - NN cord-015569-vy49r1zd 583 12 receptor receptor NN cord-015569-vy49r1zd 583 13 ( ( -LRB- cord-015569-vy49r1zd 583 14 Orco Orco NNP cord-015569-vy49r1zd 583 15 ) ) -RRB- cord-015569-vy49r1zd 583 16 as as RB cord-015569-vy49r1zd 583 17 well well RB cord-015569-vy49r1zd 583 18 as as IN cord-015569-vy49r1zd 583 19 a a DT cord-015569-vy49r1zd 583 20 calcium calcium NN cord-015569-vy49r1zd 583 21 indicator indicator NN cord-015569-vy49r1zd 583 22 protein protein NN cord-015569-vy49r1zd 583 23 , , , cord-015569-vy49r1zd 583 24 GCaMP3 GCaMP3 NNP cord-015569-vy49r1zd 583 25 , , , cord-015569-vy49r1zd 583 26 into into IN cord-015569-vy49r1zd 583 27 Spodoptera Spodoptera NNP cord-015569-vy49r1zd 583 28 frugiperda frugiperda NN cord-015569-vy49r1zd 583 29 Sf21 sf21 NN cord-015569-vy49r1zd 584 1 cells cell NNS cord-015569-vy49r1zd 584 2 to to TO cord-015569-vy49r1zd 584 3 construct construct VB cord-015569-vy49r1zd 584 4 sensor sensor NN cord-015569-vy49r1zd 584 5 cell cell NN cord-015569-vy49r1zd 584 6 lines line NNS cord-015569-vy49r1zd 584 7 . . . cord-015569-vy49r1zd 585 1 When when WRB cord-015569-vy49r1zd 585 2 these these DT cord-015569-vy49r1zd 585 3 cells cell NNS cord-015569-vy49r1zd 585 4 were be VBD cord-015569-vy49r1zd 585 5 stimulated stimulate VBN cord-015569-vy49r1zd 585 6 with with IN cord-015569-vy49r1zd 585 7 a a DT cord-015569-vy49r1zd 585 8 set set NN cord-015569-vy49r1zd 585 9 of of IN cord-015569-vy49r1zd 585 10 odorants odorant NNS cord-015569-vy49r1zd 585 11 in in IN cord-015569-vy49r1zd 585 12 solution solution NN cord-015569-vy49r1zd 585 13 , , , cord-015569-vy49r1zd 585 14 intracellular intracellular JJ cord-015569-vy49r1zd 585 15 calcium calcium NN cord-015569-vy49r1zd 585 16 as as IN cord-015569-vy49r1zd 585 17 monitored monitor VBN cord-015569-vy49r1zd 585 18 by by IN cord-015569-vy49r1zd 585 19 fluorescence fluorescence NN cord-015569-vy49r1zd 585 20 imaging imaging NN cord-015569-vy49r1zd 585 21 showed show VBD cord-015569-vy49r1zd 585 22 sensitive sensitive JJ cord-015569-vy49r1zd 585 23 responses response NNS cord-015569-vy49r1zd 585 24 in in IN cord-015569-vy49r1zd 585 25 accordance accordance NN cord-015569-vy49r1zd 585 26 to to IN cord-015569-vy49r1zd 585 27 the the DT cord-015569-vy49r1zd 585 28 ligand ligand NN cord-015569-vy49r1zd 585 29 specificity specificity NN cord-015569-vy49r1zd 585 30 of of IN cord-015569-vy49r1zd 585 31 the the DT cord-015569-vy49r1zd 585 32 expressed express VBN cord-015569-vy49r1zd 585 33 odorant odorant NN cord-015569-vy49r1zd 585 34 receptors receptor NNS cord-015569-vy49r1zd 585 35 . . . cord-015569-vy49r1zd 586 1 These these DT cord-015569-vy49r1zd 586 2 results result NNS cord-015569-vy49r1zd 586 3 show show VBP cord-015569-vy49r1zd 586 4 that that IN cord-015569-vy49r1zd 586 5 our -PRON- PRP$ cord-015569-vy49r1zd 586 6 sensor sensor NN cord-015569-vy49r1zd 586 7 cells cell NNS cord-015569-vy49r1zd 586 8 can can MD cord-015569-vy49r1zd 586 9 be be VB cord-015569-vy49r1zd 586 10 applied apply VBN cord-015569-vy49r1zd 586 11 as as IN cord-015569-vy49r1zd 586 12 odorant odorant NN cord-015569-vy49r1zd 586 13 sensor sensor NN cord-015569-vy49r1zd 586 14 elements element NNS cord-015569-vy49r1zd 586 15 that that WDT cord-015569-vy49r1zd 586 16 detect detect VBP cord-015569-vy49r1zd 586 17 various various JJ cord-015569-vy49r1zd 586 18 kinds kind NNS cord-015569-vy49r1zd 586 19 of of IN cord-015569-vy49r1zd 586 20 odorants odorant NNS cord-015569-vy49r1zd 586 21 with with IN cord-015569-vy49r1zd 586 22 high high JJ cord-015569-vy49r1zd 586 23 sensitivity sensitivity NN cord-015569-vy49r1zd 586 24 , , , cord-015569-vy49r1zd 586 25 selectivity selectivity NN cord-015569-vy49r1zd 586 26 , , , cord-015569-vy49r1zd 586 27 and and CC cord-015569-vy49r1zd 586 28 stability stability NN cord-015569-vy49r1zd 586 29 . . . cord-015569-vy49r1zd 587 1 With with IN cord-015569-vy49r1zd 587 2 promotion promotion NN cord-015569-vy49r1zd 587 3 of of IN cord-015569-vy49r1zd 587 4 globalization globalization NN cord-015569-vy49r1zd 587 5 , , , cord-015569-vy49r1zd 587 6 our -PRON- PRP$ cord-015569-vy49r1zd 587 7 diet diet NN cord-015569-vy49r1zd 587 8 are be VBP cord-015569-vy49r1zd 587 9 changing change VBG cord-015569-vy49r1zd 587 10 in in IN cord-015569-vy49r1zd 587 11 several several JJ cord-015569-vy49r1zd 587 12 directions direction NNS cord-015569-vy49r1zd 587 13 ( ( -LRB- cord-015569-vy49r1zd 587 14 diversification diversification NN cord-015569-vy49r1zd 587 15 , , , cord-015569-vy49r1zd 587 16 mass mass NN cord-015569-vy49r1zd 587 17 commercialization commercialization NN cord-015569-vy49r1zd 587 18 , , , cord-015569-vy49r1zd 587 19 or or CC cord-015569-vy49r1zd 587 20 high high JJ cord-015569-vy49r1zd 587 21 quality quality NN cord-015569-vy49r1zd 587 22 ) ) -RRB- cord-015569-vy49r1zd 587 23 . . . cord-015569-vy49r1zd 588 1 Because because IN cord-015569-vy49r1zd 588 2 of of IN cord-015569-vy49r1zd 588 3 the the DT cord-015569-vy49r1zd 588 4 change change NN cord-015569-vy49r1zd 588 5 , , , cord-015569-vy49r1zd 588 6 objective objective JJ cord-015569-vy49r1zd 588 7 evaluation evaluation NN cord-015569-vy49r1zd 588 8 techniques technique NNS cord-015569-vy49r1zd 588 9 for for IN cord-015569-vy49r1zd 588 10 taste taste NN cord-015569-vy49r1zd 588 11 or or CC cord-015569-vy49r1zd 588 12 odor odor NN cord-015569-vy49r1zd 588 13 of of IN cord-015569-vy49r1zd 588 14 foods food NNS cord-015569-vy49r1zd 588 15 and and CC cord-015569-vy49r1zd 588 16 beverages beverage NNS cord-015569-vy49r1zd 588 17 are be VBP cord-015569-vy49r1zd 588 18 needed need VBN cord-015569-vy49r1zd 588 19 for for IN cord-015569-vy49r1zd 588 20 effective effective JJ cord-015569-vy49r1zd 588 21 R&D r&d NN cord-015569-vy49r1zd 588 22 and and CC cord-015569-vy49r1zd 588 23 strict strict JJ cord-015569-vy49r1zd 588 24 quality quality NN cord-015569-vy49r1zd 588 25 control control NN cord-015569-vy49r1zd 588 26 . . . cord-015569-vy49r1zd 589 1 In in IN cord-015569-vy49r1zd 589 2 recent recent JJ cord-015569-vy49r1zd 589 3 years year NNS cord-015569-vy49r1zd 589 4 , , , cord-015569-vy49r1zd 589 5 biomimetic biomimetic JJ cord-015569-vy49r1zd 589 6 sensors sensor NNS cord-015569-vy49r1zd 589 7 , , , cord-015569-vy49r1zd 589 8 such such JJ cord-015569-vy49r1zd 589 9 as as IN cord-015569-vy49r1zd 589 10 taste taste NN cord-015569-vy49r1zd 589 11 sensor sensor NN cord-015569-vy49r1zd 589 12 , , , cord-015569-vy49r1zd 589 13 have have VBP cord-015569-vy49r1zd 589 14 been be VBN cord-015569-vy49r1zd 589 15 more more RBR cord-015569-vy49r1zd 589 16 developed develop VBN cord-015569-vy49r1zd 589 17 as as IN cord-015569-vy49r1zd 589 18 practical practical JJ cord-015569-vy49r1zd 589 19 objective objective JJ cord-015569-vy49r1zd 589 20 evaluation evaluation NN cord-015569-vy49r1zd 589 21 tools tool NNS cord-015569-vy49r1zd 589 22 for for IN cord-015569-vy49r1zd 589 23 taste taste NN cord-015569-vy49r1zd 589 24 or or CC cord-015569-vy49r1zd 589 25 odor odor NN cord-015569-vy49r1zd 589 26 . . . cord-015569-vy49r1zd 590 1 With with IN cord-015569-vy49r1zd 590 2 development development NN cord-015569-vy49r1zd 590 3 of of IN cord-015569-vy49r1zd 590 4 these these DT cord-015569-vy49r1zd 590 5 sensors sensor NNS cord-015569-vy49r1zd 590 6 , , , cord-015569-vy49r1zd 590 7 development development NN cord-015569-vy49r1zd 590 8 of of IN cord-015569-vy49r1zd 590 9 correlativity correlativity NN cord-015569-vy49r1zd 590 10 evaluation evaluation NN cord-015569-vy49r1zd 590 11 system system NN cord-015569-vy49r1zd 590 12 between between IN cord-015569-vy49r1zd 590 13 objective objective JJ cord-015569-vy49r1zd 590 14 values value NNS cord-015569-vy49r1zd 590 15 ( ( -LRB- cord-015569-vy49r1zd 590 16 sensor sensor NN cord-015569-vy49r1zd 590 17 outputs output NNS cord-015569-vy49r1zd 590 18 ) ) -RRB- cord-015569-vy49r1zd 590 19 and and CC cord-015569-vy49r1zd 590 20 subjective subjective JJ cord-015569-vy49r1zd 590 21 values value NNS cord-015569-vy49r1zd 590 22 ( ( -LRB- cord-015569-vy49r1zd 590 23 sensory sensory JJ cord-015569-vy49r1zd 590 24 scores score NNS cord-015569-vy49r1zd 590 25 ) ) -RRB- cord-015569-vy49r1zd 590 26 is be VBZ cord-015569-vy49r1zd 590 27 needed need VBN cord-015569-vy49r1zd 590 28 to to TO cord-015569-vy49r1zd 590 29 realize realize VB cord-015569-vy49r1zd 590 30 objective objective JJ cord-015569-vy49r1zd 590 31 quality quality NN cord-015569-vy49r1zd 590 32 evaluation evaluation NN cord-015569-vy49r1zd 590 33 of of IN cord-015569-vy49r1zd 590 34 foods food NNS cord-015569-vy49r1zd 590 35 and and CC cord-015569-vy49r1zd 590 36 beverages beverage NNS cord-015569-vy49r1zd 590 37 . . . cord-015569-vy49r1zd 591 1 Mainly mainly RB cord-015569-vy49r1zd 591 2 developing develop VBG cord-015569-vy49r1zd 591 3 artificial artificial JJ cord-015569-vy49r1zd 591 4 - - HYPH cord-015569-vy49r1zd 591 5 lipids lipid NNS cord-015569-vy49r1zd 591 6 - - HYPH cord-015569-vy49r1zd 591 7 based base VBN cord-015569-vy49r1zd 591 8 taste taste NN cord-015569-vy49r1zd 591 9 sensors sensor NNS cord-015569-vy49r1zd 591 10 with with IN cord-015569-vy49r1zd 591 11 global global JJ cord-015569-vy49r1zd 591 12 selectivity selectivity NN cord-015569-vy49r1zd 591 13 , , , cord-015569-vy49r1zd 591 14 our -PRON- PRP$ cord-015569-vy49r1zd 591 15 research research NN cord-015569-vy49r1zd 591 16 group group NN cord-015569-vy49r1zd 591 17 have have VBP cord-015569-vy49r1zd 591 18 studied study VBN cord-015569-vy49r1zd 591 19 for for IN cord-015569-vy49r1zd 591 20 realization realization NN cord-015569-vy49r1zd 591 21 of of IN cord-015569-vy49r1zd 591 22 Ôtaste Ôtaste NNP cord-015569-vy49r1zd 591 23 - - HYPH cord-015569-vy49r1zd 591 24 odor odor NN cord-015569-vy49r1zd 591 25 fusion fusion NN cord-015569-vy49r1zd 591 26 biosensor biosensor NN cord-015569-vy49r1zd 591 27 system system NN cord-015569-vy49r1zd 591 28 , , , cord-015569-vy49r1zd 591 29 Õ Õ NNP cord-015569-vy49r1zd 591 30 which which WDT cord-015569-vy49r1zd 591 31 estimates estimate VBZ cord-015569-vy49r1zd 591 32 quality quality NN cord-015569-vy49r1zd 591 33 ( ( -LRB- cord-015569-vy49r1zd 591 34 deliciousness deliciousness NN cord-015569-vy49r1zd 591 35 and and CC cord-015569-vy49r1zd 591 36 safety safety NN cord-015569-vy49r1zd 591 37 ) ) -RRB- cord-015569-vy49r1zd 591 38 of of IN cord-015569-vy49r1zd 591 39 foods food NNS cord-015569-vy49r1zd 591 40 or or CC cord-015569-vy49r1zd 591 41 beverages beverage NNS cord-015569-vy49r1zd 591 42 using use VBG cord-015569-vy49r1zd 591 43 several several JJ cord-015569-vy49r1zd 591 44 sensor sensor NN cord-015569-vy49r1zd 591 45 outputs output NNS cord-015569-vy49r1zd 591 46 through through IN cord-015569-vy49r1zd 591 47 analysis analysis NN cord-015569-vy49r1zd 591 48 and and CC cord-015569-vy49r1zd 591 49 evaluation evaluation NN cord-015569-vy49r1zd 591 50 of of IN cord-015569-vy49r1zd 591 51 subjective subjective JJ cord-015569-vy49r1zd 591 52 - - HYPH cord-015569-vy49r1zd 591 53 objective objective JJ cord-015569-vy49r1zd 591 54 relation relation NN cord-015569-vy49r1zd 591 55 . . . cord-015569-vy49r1zd 592 1 In in IN cord-015569-vy49r1zd 592 2 the the DT cord-015569-vy49r1zd 592 3 studies study NNS cord-015569-vy49r1zd 592 4 , , , cord-015569-vy49r1zd 592 5 we -PRON- PRP cord-015569-vy49r1zd 592 6 have have VBP cord-015569-vy49r1zd 592 7 estimated estimate VBN cord-015569-vy49r1zd 592 8 relations relation NNS cord-015569-vy49r1zd 592 9 between between IN cord-015569-vy49r1zd 592 10 each each DT cord-015569-vy49r1zd 592 11 taste taste NN cord-015569-vy49r1zd 592 12 sensory sensory JJ cord-015569-vy49r1zd 592 13 and and CC cord-015569-vy49r1zd 592 14 each each DT cord-015569-vy49r1zd 592 15 sensor sensor NN cord-015569-vy49r1zd 592 16 output output NN cord-015569-vy49r1zd 592 17 , , , cord-015569-vy49r1zd 592 18 but but CC cord-015569-vy49r1zd 592 19 did do VBD cord-015569-vy49r1zd 592 20 not not RB cord-015569-vy49r1zd 592 21 investigate investigate VB cord-015569-vy49r1zd 592 22 about about IN cord-015569-vy49r1zd 592 23 correlativity correlativity NN cord-015569-vy49r1zd 592 24 among among IN cord-015569-vy49r1zd 592 25 quality quality NN cord-015569-vy49r1zd 592 26 of of IN cord-015569-vy49r1zd 592 27 foods food NNS cord-015569-vy49r1zd 592 28 or or CC cord-015569-vy49r1zd 592 29 beverages beverage NNS cord-015569-vy49r1zd 592 30 and and CC cord-015569-vy49r1zd 592 31 sensor sensor NN cord-015569-vy49r1zd 592 32 outputs output NNS cord-015569-vy49r1zd 592 33 . . . cord-015569-vy49r1zd 593 1 Hence hence RB cord-015569-vy49r1zd 593 2 , , , cord-015569-vy49r1zd 593 3 in in IN cord-015569-vy49r1zd 593 4 this this DT cord-015569-vy49r1zd 593 5 study study NN cord-015569-vy49r1zd 593 6 , , , cord-015569-vy49r1zd 593 7 we -PRON- PRP cord-015569-vy49r1zd 593 8 investigated investigate VBD cord-015569-vy49r1zd 593 9 correlativity correlativity NN cord-015569-vy49r1zd 593 10 among among IN cord-015569-vy49r1zd 593 11 sensory sensory NN cord-015569-vy49r1zd 593 12 of of IN cord-015569-vy49r1zd 593 13 deliciousness deliciousness NN cord-015569-vy49r1zd 593 14 and and CC cord-015569-vy49r1zd 593 15 several several JJ cord-015569-vy49r1zd 593 16 sensorsÕ sensorsÕ NNP cord-015569-vy49r1zd 593 17 outputs output NNS cord-015569-vy49r1zd 593 18 on on IN cord-015569-vy49r1zd 593 19 a a DT cord-015569-vy49r1zd 593 20 particular particular JJ cord-015569-vy49r1zd 593 21 sample sample NN cord-015569-vy49r1zd 593 22 as as IN cord-015569-vy49r1zd 593 23 the the DT cord-015569-vy49r1zd 593 24 next next JJ cord-015569-vy49r1zd 593 25 step step NN cord-015569-vy49r1zd 593 26 of of IN cord-015569-vy49r1zd 593 27 realizing realize VBG cord-015569-vy49r1zd 593 28 Ôtaste Ôtaste NNP cord-015569-vy49r1zd 593 29 - - HYPH cord-015569-vy49r1zd 593 30 odor odor NN cord-015569-vy49r1zd 593 31 fusion fusion NN cord-015569-vy49r1zd 593 32 biosensor biosensor NN cord-015569-vy49r1zd 593 33 system system NN cord-015569-vy49r1zd 593 34 . . . cord-015569-vy49r1zd 594 1 Õ õ RB cord-015569-vy49r1zd 595 1 As as IN cord-015569-vy49r1zd 595 2 a a DT cord-015569-vy49r1zd 595 3 result result NN cord-015569-vy49r1zd 595 4 , , , cord-015569-vy49r1zd 595 5 we -PRON- PRP cord-015569-vy49r1zd 595 6 found find VBD cord-015569-vy49r1zd 595 7 that that IN cord-015569-vy49r1zd 595 8 sensory sensory JJ cord-015569-vy49r1zd 595 9 scores score NNS cord-015569-vy49r1zd 595 10 of of IN cord-015569-vy49r1zd 595 11 deliciousness deliciousness NN cord-015569-vy49r1zd 595 12 were be VBD cord-015569-vy49r1zd 595 13 able able JJ cord-015569-vy49r1zd 595 14 to to TO cord-015569-vy49r1zd 595 15 be be VB cord-015569-vy49r1zd 595 16 displayed display VBN cord-015569-vy49r1zd 595 17 on on IN cord-015569-vy49r1zd 595 18 a a DT cord-015569-vy49r1zd 595 19 superspace superspace NN cord-015569-vy49r1zd 595 20 as as IN cord-015569-vy49r1zd 595 21 a a DT cord-015569-vy49r1zd 595 22 hyperplane hyperplane NN cord-015569-vy49r1zd 595 23 and and CC cord-015569-vy49r1zd 595 24 to to TO cord-015569-vy49r1zd 595 25 be be VB cord-015569-vy49r1zd 595 26 estimated estimate VBN cord-015569-vy49r1zd 595 27 by by IN cord-015569-vy49r1zd 595 28 the the DT cord-015569-vy49r1zd 595 29 hyperplane hyperplane NN cord-015569-vy49r1zd 595 30 and and CC cord-015569-vy49r1zd 595 31 sensor sensor NN cord-015569-vy49r1zd 595 32 outputs output NNS cord-015569-vy49r1zd 595 33 . . . cord-015569-vy49r1zd 596 1 This this DT cord-015569-vy49r1zd 596 2 means mean VBZ cord-015569-vy49r1zd 596 3 that that IN cord-015569-vy49r1zd 596 4 a a DT cord-015569-vy49r1zd 596 5 sensory sensory JJ cord-015569-vy49r1zd 596 6 score score NN cord-015569-vy49r1zd 596 7 on on IN cord-015569-vy49r1zd 596 8 the the DT cord-015569-vy49r1zd 596 9 particular particular JJ cord-015569-vy49r1zd 596 10 sample sample NN cord-015569-vy49r1zd 596 11 can can MD cord-015569-vy49r1zd 596 12 be be VB cord-015569-vy49r1zd 596 13 calculated calculate VBN cord-015569-vy49r1zd 596 14 using use VBG cord-015569-vy49r1zd 596 15 sensor sensor NN cord-015569-vy49r1zd 596 16 outputs output NNS cord-015569-vy49r1zd 596 17 and and CC cord-015569-vy49r1zd 596 18 an an DT cord-015569-vy49r1zd 596 19 estimation estimation NN cord-015569-vy49r1zd 596 20 equation equation NN cord-015569-vy49r1zd 596 21 indicating indicate VBG cord-015569-vy49r1zd 596 22 the the DT cord-015569-vy49r1zd 596 23 hyperplane hyperplane NN cord-015569-vy49r1zd 596 24 . . . cord-015569-vy49r1zd 597 1 It -PRON- PRP cord-015569-vy49r1zd 597 2 has have VBZ cord-015569-vy49r1zd 597 3 been be VBN cord-015569-vy49r1zd 597 4 reported report VBN cord-015569-vy49r1zd 597 5 that that IN cord-015569-vy49r1zd 597 6 taste taste NN cord-015569-vy49r1zd 597 7 disorder disorder NN cord-015569-vy49r1zd 597 8 caused cause VBN cord-015569-vy49r1zd 597 9 by by IN cord-015569-vy49r1zd 597 10 systemic systemic JJ cord-015569-vy49r1zd 597 11 diseases disease NNS cord-015569-vy49r1zd 597 12 is be VBZ cord-015569-vy49r1zd 597 13 associated associate VBN cord-015569-vy49r1zd 597 14 with with IN cord-015569-vy49r1zd 597 15 zinc zinc NN cord-015569-vy49r1zd 597 16 deficiency deficiency NN cord-015569-vy49r1zd 597 17 . . . cord-015569-vy49r1zd 598 1 This this DT cord-015569-vy49r1zd 598 2 study study NN cord-015569-vy49r1zd 598 3 included include VBD cord-015569-vy49r1zd 598 4 101 101 CD cord-015569-vy49r1zd 598 5 patients patient NNS cord-015569-vy49r1zd 598 6 with with IN cord-015569-vy49r1zd 598 7 dysgeusia dysgeusia NNS cord-015569-vy49r1zd 598 8 due due JJ cord-015569-vy49r1zd 598 9 to to IN cord-015569-vy49r1zd 598 10 systemic systemic JJ cord-015569-vy49r1zd 598 11 diseases disease NNS cord-015569-vy49r1zd 598 12 : : : cord-015569-vy49r1zd 598 13 30 30 CD cord-015569-vy49r1zd 598 14 patients patient NNS cord-015569-vy49r1zd 598 15 with with IN cord-015569-vy49r1zd 598 16 diabetes diabetes NN cord-015569-vy49r1zd 598 17 mellitus mellitus NN cord-015569-vy49r1zd 598 18 ( ( -LRB- cord-015569-vy49r1zd 598 19 DM DM NNP cord-015569-vy49r1zd 598 20 ) ) -RRB- cord-015569-vy49r1zd 598 21 , , , cord-015569-vy49r1zd 598 22 21 21 CD cord-015569-vy49r1zd 598 23 with with IN cord-015569-vy49r1zd 598 24 renal renal JJ cord-015569-vy49r1zd 598 25 failures failure NNS cord-015569-vy49r1zd 598 26 , , , cord-015569-vy49r1zd 598 27 19 19 CD cord-015569-vy49r1zd 598 28 with with IN cord-015569-vy49r1zd 598 29 digestive digestive JJ cord-015569-vy49r1zd 598 30 diseases disease NNS cord-015569-vy49r1zd 598 31 , , , cord-015569-vy49r1zd 598 32 21 21 CD cord-015569-vy49r1zd 598 33 with with IN cord-015569-vy49r1zd 598 34 digestive digestive JJ cord-015569-vy49r1zd 598 35 diseases disease NNS cord-015569-vy49r1zd 598 36 post post NN cord-015569-vy49r1zd 598 37 operation operation NN cord-015569-vy49r1zd 598 38 , , , cord-015569-vy49r1zd 598 39 and and CC cord-015569-vy49r1zd 598 40 8 8 CD cord-015569-vy49r1zd 598 41 with with IN cord-015569-vy49r1zd 598 42 liver liver NN cord-015569-vy49r1zd 598 43 failure failure NN cord-015569-vy49r1zd 598 44 . . . cord-015569-vy49r1zd 599 1 Taste taste NN cord-015569-vy49r1zd 599 2 function function NN cord-015569-vy49r1zd 599 3 was be VBD cord-015569-vy49r1zd 599 4 tested test VBN cord-015569-vy49r1zd 599 5 by by IN cord-015569-vy49r1zd 599 6 electrogustometry electrogustometry NNP cord-015569-vy49r1zd 599 7 ( ( -LRB- cord-015569-vy49r1zd 599 8 EGM EGM NNP cord-015569-vy49r1zd 599 9 ) ) -RRB- cord-015569-vy49r1zd 599 10 and and CC cord-015569-vy49r1zd 599 11 filter filter VB cord-015569-vy49r1zd 599 12 paper paper NN cord-015569-vy49r1zd 599 13 disk disk NN cord-015569-vy49r1zd 599 14 method method NN cord-015569-vy49r1zd 599 15 ( ( -LRB- cord-015569-vy49r1zd 599 16 FPD FPD NNP cord-015569-vy49r1zd 599 17 method method NN cord-015569-vy49r1zd 599 18 ) ) -RRB- cord-015569-vy49r1zd 599 19 in in IN cord-015569-vy49r1zd 599 20 the the DT cord-015569-vy49r1zd 599 21 area area NN cord-015569-vy49r1zd 599 22 controlled control VBN cord-015569-vy49r1zd 599 23 by by IN cord-015569-vy49r1zd 599 24 the the DT cord-015569-vy49r1zd 599 25 chorda chorda NNP cord-015569-vy49r1zd 599 26 tympani tympani NN cord-015569-vy49r1zd 599 27 nerve nerve NN cord-015569-vy49r1zd 599 28 . . . cord-015569-vy49r1zd 600 1 The the DT cord-015569-vy49r1zd 600 2 severe severe JJ cord-015569-vy49r1zd 600 3 grades grade NNS cord-015569-vy49r1zd 600 4 of of IN cord-015569-vy49r1zd 600 5 taste taste NN cord-015569-vy49r1zd 600 6 threshold threshold NN cord-015569-vy49r1zd 600 7 before before IN cord-015569-vy49r1zd 600 8 treatment treatment NN cord-015569-vy49r1zd 600 9 were be VBD cord-015569-vy49r1zd 600 10 more more JJR cord-015569-vy49r1zd 600 11 than than IN cord-015569-vy49r1zd 600 12 60 60 CD cord-015569-vy49r1zd 600 13 % % NN cord-015569-vy49r1zd 600 14 for for IN cord-015569-vy49r1zd 600 15 renal renal JJ cord-015569-vy49r1zd 600 16 and and CC cord-015569-vy49r1zd 600 17 liver liver NN cord-015569-vy49r1zd 600 18 failure failure NN cord-015569-vy49r1zd 600 19 patients patient NNS cord-015569-vy49r1zd 600 20 . . . cord-015569-vy49r1zd 601 1 All all DT cord-015569-vy49r1zd 601 2 patients patient NNS cord-015569-vy49r1zd 601 3 were be VBD cord-015569-vy49r1zd 601 4 treated treat VBN cord-015569-vy49r1zd 601 5 with with IN cord-015569-vy49r1zd 601 6 zinc zinc NN cord-015569-vy49r1zd 601 7 sulfate sulfate NN cord-015569-vy49r1zd 601 8 . . . cord-015569-vy49r1zd 602 1 The the DT cord-015569-vy49r1zd 602 2 rates rate NNS cord-015569-vy49r1zd 602 3 of of IN cord-015569-vy49r1zd 602 4 serum serum NN cord-015569-vy49r1zd 602 5 zinc zinc NN cord-015569-vy49r1zd 602 6 deficiency deficiency NN cord-015569-vy49r1zd 602 7 ( ( -LRB- cord-015569-vy49r1zd 602 8 < < NNP cord-015569-vy49r1zd 602 9 80 80 CD cord-015569-vy49r1zd 602 10 lg lg NNP cord-015569-vy49r1zd 602 11 / / SYM cord-015569-vy49r1zd 602 12 dl dl NNP cord-015569-vy49r1zd 602 13 ) ) -RRB- cord-015569-vy49r1zd 602 14 were be VBD cord-015569-vy49r1zd 602 15 more more JJR cord-015569-vy49r1zd 602 16 than than IN cord-015569-vy49r1zd 602 17 80 80 CD cord-015569-vy49r1zd 602 18 % % NN cord-015569-vy49r1zd 602 19 for for IN cord-015569-vy49r1zd 602 20 all all DT cord-015569-vy49r1zd 602 21 systemic systemic JJ cord-015569-vy49r1zd 602 22 diseases disease NNS cord-015569-vy49r1zd 602 23 . . . cord-015569-vy49r1zd 603 1 In in IN cord-015569-vy49r1zd 603 2 patients patient NNS cord-015569-vy49r1zd 603 3 with with IN cord-015569-vy49r1zd 603 4 renal renal JJ cord-015569-vy49r1zd 603 5 failure failure NN cord-015569-vy49r1zd 603 6 , , , cord-015569-vy49r1zd 603 7 the the DT cord-015569-vy49r1zd 603 8 symptom symptom NN cord-015569-vy49r1zd 603 9 improvement improvement NN cord-015569-vy49r1zd 603 10 rate rate NN cord-015569-vy49r1zd 603 11 was be VBD cord-015569-vy49r1zd 603 12 the the DT cord-015569-vy49r1zd 603 13 highest high JJS cord-015569-vy49r1zd 603 14 , , , cord-015569-vy49r1zd 603 15 and and CC cord-015569-vy49r1zd 603 16 the the DT cord-015569-vy49r1zd 603 17 curative curative JJ cord-015569-vy49r1zd 603 18 period period NN cord-015569-vy49r1zd 603 19 was be VBD cord-015569-vy49r1zd 603 20 shortest short JJS cord-015569-vy49r1zd 603 21 . . . cord-015569-vy49r1zd 604 1 However however RB cord-015569-vy49r1zd 604 2 , , , cord-015569-vy49r1zd 604 3 in in IN cord-015569-vy49r1zd 604 4 DM DM NNP cord-015569-vy49r1zd 604 5 patients patient NNS cord-015569-vy49r1zd 604 6 , , , cord-015569-vy49r1zd 604 7 the the DT cord-015569-vy49r1zd 604 8 improvement improvement NN cord-015569-vy49r1zd 604 9 rate rate NN cord-015569-vy49r1zd 604 10 was be VBD cord-015569-vy49r1zd 604 11 the the DT cord-015569-vy49r1zd 604 12 lowest low JJS cord-015569-vy49r1zd 604 13 , , , cord-015569-vy49r1zd 604 14 and and CC cord-015569-vy49r1zd 604 15 the the DT cord-015569-vy49r1zd 604 16 curative curative JJ cord-015569-vy49r1zd 604 17 period period NN cord-015569-vy49r1zd 604 18 was be VBD cord-015569-vy49r1zd 604 19 longest long JJS cord-015569-vy49r1zd 604 20 . . . cord-015569-vy49r1zd 605 1 This this DT cord-015569-vy49r1zd 605 2 study study NN cord-015569-vy49r1zd 605 3 demonstrated demonstrate VBD cord-015569-vy49r1zd 605 4 that that IN cord-015569-vy49r1zd 605 5 zinc zinc NN cord-015569-vy49r1zd 605 6 deficiency deficiency NN cord-015569-vy49r1zd 605 7 is be VBZ cord-015569-vy49r1zd 605 8 induced induce VBN cord-015569-vy49r1zd 605 9 by by IN cord-015569-vy49r1zd 605 10 systemic systemic JJ cord-015569-vy49r1zd 605 11 diseases disease NNS cord-015569-vy49r1zd 605 12 , , , cord-015569-vy49r1zd 605 13 and and CC cord-015569-vy49r1zd 605 14 might may MD cord-015569-vy49r1zd 605 15 cause cause VB cord-015569-vy49r1zd 605 16 taste taste NN cord-015569-vy49r1zd 605 17 disorder disorder NN cord-015569-vy49r1zd 605 18 . . . cord-015569-vy49r1zd 606 1 It -PRON- PRP cord-015569-vy49r1zd 606 2 is be VBZ cord-015569-vy49r1zd 606 3 also also RB cord-015569-vy49r1zd 606 4 necessary necessary JJ cord-015569-vy49r1zd 606 5 to to TO cord-015569-vy49r1zd 606 6 consider consider VB cord-015569-vy49r1zd 606 7 the the DT cord-015569-vy49r1zd 606 8 possibility possibility NN cord-015569-vy49r1zd 606 9 of of IN cord-015569-vy49r1zd 606 10 taste taste NN cord-015569-vy49r1zd 606 11 disorder disorder NN cord-015569-vy49r1zd 606 12 caused cause VBN cord-015569-vy49r1zd 606 13 by by IN cord-015569-vy49r1zd 606 14 medication medication NN cord-015569-vy49r1zd 606 15 . . . cord-015569-vy49r1zd 607 1 This this DT cord-015569-vy49r1zd 607 2 study study NN cord-015569-vy49r1zd 607 3 analyzed analyze VBD cord-015569-vy49r1zd 607 4 124 124 CD cord-015569-vy49r1zd 607 5 patients patient NNS cord-015569-vy49r1zd 607 6 with with IN cord-015569-vy49r1zd 607 7 BMS BMS NNP cord-015569-vy49r1zd 607 8 . . . cord-015569-vy49r1zd 608 1 The the DT cord-015569-vy49r1zd 608 2 threshold threshold NN cord-015569-vy49r1zd 608 3 of of IN cord-015569-vy49r1zd 608 4 the the DT cord-015569-vy49r1zd 608 5 taste taste NN cord-015569-vy49r1zd 608 6 function function NN cord-015569-vy49r1zd 608 7 was be VBD cord-015569-vy49r1zd 608 8 measured measure VBN cord-015569-vy49r1zd 608 9 by by IN cord-015569-vy49r1zd 608 10 electrogustometry electrogustometry NNP cord-015569-vy49r1zd 608 11 ( ( -LRB- cord-015569-vy49r1zd 608 12 EGM EGM NNP cord-015569-vy49r1zd 608 13 ) ) -RRB- cord-015569-vy49r1zd 608 14 and and CC cord-015569-vy49r1zd 608 15 the the DT cord-015569-vy49r1zd 608 16 filter filter NN cord-015569-vy49r1zd 608 17 - - HYPH cord-015569-vy49r1zd 608 18 paper paper NN cord-015569-vy49r1zd 608 19 disk disk NN cord-015569-vy49r1zd 608 20 ( ( -LRB- cord-015569-vy49r1zd 608 21 FPD FPD NNP cord-015569-vy49r1zd 608 22 ) ) -RRB- cord-015569-vy49r1zd 608 23 method method NN cord-015569-vy49r1zd 608 24 . . . cord-015569-vy49r1zd 609 1 Both both DT cord-015569-vy49r1zd 609 2 basal basal NN cord-015569-vy49r1zd 609 3 and and CC cord-015569-vy49r1zd 609 4 stimulated stimulate VBD cord-015569-vy49r1zd 609 5 salivary salivary JJ cord-015569-vy49r1zd 609 6 secretions secretion NNS cord-015569-vy49r1zd 609 7 were be VBD cord-015569-vy49r1zd 609 8 measured measure VBN cord-015569-vy49r1zd 609 9 . . . cord-015569-vy49r1zd 610 1 In in IN cord-015569-vy49r1zd 610 2 addition addition NN cord-015569-vy49r1zd 610 3 , , , cord-015569-vy49r1zd 610 4 the the DT cord-015569-vy49r1zd 610 5 self self NN cord-015569-vy49r1zd 610 6 - - HYPH cord-015569-vy49r1zd 610 7 rating rate VBG cord-015569-vy49r1zd 610 8 depression depression NN cord-015569-vy49r1zd 610 9 scale scale NN cord-015569-vy49r1zd 610 10 ( ( -LRB- cord-015569-vy49r1zd 610 11 SDS SDS NNP cord-015569-vy49r1zd 610 12 ) ) -RRB- cord-015569-vy49r1zd 610 13 was be VBD cord-015569-vy49r1zd 610 14 assessed assess VBN cord-015569-vy49r1zd 610 15 . . . cord-015569-vy49r1zd 611 1 Serum serum NN cord-015569-vy49r1zd 611 2 zinc zinc NN cord-015569-vy49r1zd 611 3 and and CC cord-015569-vy49r1zd 611 4 copper copper NN cord-015569-vy49r1zd 611 5 levels level NNS cord-015569-vy49r1zd 611 6 were be VBD cord-015569-vy49r1zd 611 7 also also RB cord-015569-vy49r1zd 611 8 measured measure VBN cord-015569-vy49r1zd 611 9 . . . cord-015569-vy49r1zd 612 1 The the DT cord-015569-vy49r1zd 612 2 EGM EGM NNP cord-015569-vy49r1zd 612 3 threshold threshold NN cord-015569-vy49r1zd 612 4 was be VBD cord-015569-vy49r1zd 612 5 more more JJR cord-015569-vy49r1zd 612 6 than than IN cord-015569-vy49r1zd 612 7 10 10 CD cord-015569-vy49r1zd 612 8 dB dB NNS cord-015569-vy49r1zd 612 9 in in IN cord-015569-vy49r1zd 612 10 80 80 CD cord-015569-vy49r1zd 612 11 ( ( -LRB- cord-015569-vy49r1zd 612 12 67.2 67.2 CD cord-015569-vy49r1zd 612 13 % % NN cord-015569-vy49r1zd 612 14 ) ) -RRB- cord-015569-vy49r1zd 612 15 of of IN cord-015569-vy49r1zd 612 16 119 119 CD cord-015569-vy49r1zd 612 17 patients patient NNS cord-015569-vy49r1zd 612 18 , , , cord-015569-vy49r1zd 612 19 and and CC cord-015569-vy49r1zd 612 20 the the DT cord-015569-vy49r1zd 612 21 taste taste NN cord-015569-vy49r1zd 612 22 threshold threshold NN cord-015569-vy49r1zd 612 23 measured measure VBN cord-015569-vy49r1zd 612 24 by by IN cord-015569-vy49r1zd 612 25 the the DT cord-015569-vy49r1zd 612 26 FPD FPD NNP cord-015569-vy49r1zd 612 27 method method NN cord-015569-vy49r1zd 612 28 was be VBD cord-015569-vy49r1zd 612 29 more more JJR cord-015569-vy49r1zd 612 30 than than IN cord-015569-vy49r1zd 612 31 4 4 CD cord-015569-vy49r1zd 612 32 points point NNS cord-015569-vy49r1zd 612 33 in in IN cord-015569-vy49r1zd 612 34 61 61 CD cord-015569-vy49r1zd 612 35 ( ( -LRB- cord-015569-vy49r1zd 612 36 51.3 51.3 CD cord-015569-vy49r1zd 612 37 % % NN cord-015569-vy49r1zd 612 38 ) ) -RRB- cord-015569-vy49r1zd 612 39 of of IN cord-015569-vy49r1zd 612 40 119 119 CD cord-015569-vy49r1zd 612 41 patients patient NNS cord-015569-vy49r1zd 612 42 . . . cord-015569-vy49r1zd 613 1 Basal basal NN cord-015569-vy49r1zd 613 2 and and CC cord-015569-vy49r1zd 613 3 stimulated stimulate VBD cord-015569-vy49r1zd 613 4 salivary salivary JJ cord-015569-vy49r1zd 613 5 secretions secretion NNS cord-015569-vy49r1zd 613 6 were be VBD cord-015569-vy49r1zd 613 7 less less JJR cord-015569-vy49r1zd 613 8 than than IN cord-015569-vy49r1zd 613 9 3 3 CD cord-015569-vy49r1zd 613 10 ml ml NNS cord-015569-vy49r1zd 613 11 in in IN cord-015569-vy49r1zd 613 12 90 90 CD cord-015569-vy49r1zd 613 13 ( ( -LRB- cord-015569-vy49r1zd 613 14 78.3 78.3 CD cord-015569-vy49r1zd 613 15 % % NN cord-015569-vy49r1zd 613 16 ) ) -RRB- cord-015569-vy49r1zd 613 17 of of IN cord-015569-vy49r1zd 613 18 115 115 CD cord-015569-vy49r1zd 613 19 patients patient NNS cord-015569-vy49r1zd 613 20 and and CC cord-015569-vy49r1zd 613 21 less less JJR cord-015569-vy49r1zd 613 22 than than IN cord-015569-vy49r1zd 613 23 10 10 CD cord-015569-vy49r1zd 613 24 ml ml NNS cord-015569-vy49r1zd 613 25 in in IN cord-015569-vy49r1zd 613 26 52 52 CD cord-015569-vy49r1zd 613 27 ( ( -LRB- cord-015569-vy49r1zd 613 28 45.2 45.2 CD cord-015569-vy49r1zd 613 29 % % NN cord-015569-vy49r1zd 613 30 ) ) -RRB- cord-015569-vy49r1zd 613 31 of of IN cord-015569-vy49r1zd 613 32 115 115 CD cord-015569-vy49r1zd 613 33 patients patient NNS cord-015569-vy49r1zd 613 34 , , , cord-015569-vy49r1zd 613 35 respectively respectively RB cord-015569-vy49r1zd 613 36 . . . cord-015569-vy49r1zd 614 1 Based base VBN cord-015569-vy49r1zd 614 2 on on IN cord-015569-vy49r1zd 614 3 the the DT cord-015569-vy49r1zd 614 4 SDS SDS NNP cord-015569-vy49r1zd 614 5 , , , cord-015569-vy49r1zd 614 6 45 45 CD cord-015569-vy49r1zd 614 7 ( ( -LRB- cord-015569-vy49r1zd 614 8 56.2 56.2 CD cord-015569-vy49r1zd 614 9 % % NN cord-015569-vy49r1zd 614 10 ) ) -RRB- cord-015569-vy49r1zd 614 11 and and CC cord-015569-vy49r1zd 614 12 14 14 CD cord-015569-vy49r1zd 614 13 ( ( -LRB- cord-015569-vy49r1zd 614 14 17.5 17.5 CD cord-015569-vy49r1zd 614 15 % % NN cord-015569-vy49r1zd 614 16 ) ) -RRB- cord-015569-vy49r1zd 614 17 of of IN cord-015569-vy49r1zd 614 18 80 80 CD cord-015569-vy49r1zd 614 19 patients patient NNS cord-015569-vy49r1zd 614 20 were be VBD cord-015569-vy49r1zd 614 21 diagnosed diagnose VBN cord-015569-vy49r1zd 614 22 with with IN cord-015569-vy49r1zd 614 23 neurosis neurosis NN cord-015569-vy49r1zd 614 24 and and CC cord-015569-vy49r1zd 614 25 depression depression NN cord-015569-vy49r1zd 614 26 , , , cord-015569-vy49r1zd 614 27 respectively respectively RB cord-015569-vy49r1zd 614 28 . . . cord-015569-vy49r1zd 615 1 Blood blood NN cord-015569-vy49r1zd 615 2 tests test NNS cord-015569-vy49r1zd 615 3 showed show VBD cord-015569-vy49r1zd 615 4 that that IN cord-015569-vy49r1zd 615 5 the the DT cord-015569-vy49r1zd 615 6 serum serum NN cord-015569-vy49r1zd 615 7 levels level NNS cord-015569-vy49r1zd 615 8 of of IN cord-015569-vy49r1zd 615 9 zinc zinc NN cord-015569-vy49r1zd 615 10 were be VBD cord-015569-vy49r1zd 615 11 less less JJR cord-015569-vy49r1zd 615 12 than than IN cord-015569-vy49r1zd 615 13 70 70 CD cord-015569-vy49r1zd 615 14 or or CC cord-015569-vy49r1zd 615 15 that that DT cord-015569-vy49r1zd 615 16 of of IN cord-015569-vy49r1zd 615 17 copper copper NN cord-015569-vy49r1zd 615 18 were be VBD cord-015569-vy49r1zd 615 19 more more JJR cord-015569-vy49r1zd 615 20 than than IN cord-015569-vy49r1zd 615 21 130 130 CD cord-015569-vy49r1zd 615 22 lg lg NNP cord-015569-vy49r1zd 615 23 / / SYM cord-015569-vy49r1zd 615 24 dL dl NN cord-015569-vy49r1zd 615 25 , , , cord-015569-vy49r1zd 615 26 respectively respectively RB cord-015569-vy49r1zd 615 27 , , , cord-015569-vy49r1zd 615 28 in in IN cord-015569-vy49r1zd 615 29 61 61 CD cord-015569-vy49r1zd 615 30 ( ( -LRB- cord-015569-vy49r1zd 615 31 54.5 54.5 CD cord-015569-vy49r1zd 615 32 % % NN cord-015569-vy49r1zd 615 33 ) ) -RRB- cord-015569-vy49r1zd 615 34 of of IN cord-015569-vy49r1zd 615 35 112 112 CD cord-015569-vy49r1zd 615 36 patients patient NNS cord-015569-vy49r1zd 615 37 . . . cord-015569-vy49r1zd 616 1 The the DT cord-015569-vy49r1zd 616 2 clinical clinical JJ cord-015569-vy49r1zd 616 3 outcome outcome NN cord-015569-vy49r1zd 616 4 was be VBD cord-015569-vy49r1zd 616 5 cure cure NN cord-015569-vy49r1zd 616 6 in in IN cord-015569-vy49r1zd 616 7 38.1 38.1 CD cord-015569-vy49r1zd 616 8 % % NN cord-015569-vy49r1zd 616 9 , , , cord-015569-vy49r1zd 616 10 improvement improvement NN cord-015569-vy49r1zd 616 11 in in IN cord-015569-vy49r1zd 616 12 13.6 13.6 CD cord-015569-vy49r1zd 616 13 % % NN cord-015569-vy49r1zd 616 14 , , , cord-015569-vy49r1zd 616 15 recurrence recurrence NN cord-015569-vy49r1zd 616 16 in in IN cord-015569-vy49r1zd 616 17 11.9 11.9 CD cord-015569-vy49r1zd 616 18 % % NN cord-015569-vy49r1zd 616 19 , , , cord-015569-vy49r1zd 616 20 unchanged unchanged JJ cord-015569-vy49r1zd 616 21 in in IN cord-015569-vy49r1zd 616 22 11.0 11.0 CD cord-015569-vy49r1zd 616 23 % % NN cord-015569-vy49r1zd 616 24 , , , cord-015569-vy49r1zd 616 25 and and CC cord-015569-vy49r1zd 616 26 dropped drop VBD cord-015569-vy49r1zd 616 27 out out RP cord-015569-vy49r1zd 616 28 in in IN cord-015569-vy49r1zd 616 29 16.9 16.9 CD cord-015569-vy49r1zd 616 30 % % NN cord-015569-vy49r1zd 616 31 . . . cord-015569-vy49r1zd 617 1 In in IN cord-015569-vy49r1zd 617 2 this this DT cord-015569-vy49r1zd 617 3 study study NN cord-015569-vy49r1zd 617 4 , , , cord-015569-vy49r1zd 617 5 basal basal NN cord-015569-vy49r1zd 617 6 salivary salivary NN cord-015569-vy49r1zd 617 7 secretions secretion NNS cord-015569-vy49r1zd 617 8 lower low JJR cord-015569-vy49r1zd 617 9 than than IN cord-015569-vy49r1zd 617 10 the the DT cord-015569-vy49r1zd 617 11 normal normal JJ cord-015569-vy49r1zd 617 12 range range NN cord-015569-vy49r1zd 617 13 compared compare VBN cord-015569-vy49r1zd 617 14 with with IN cord-015569-vy49r1zd 617 15 stimulated stimulate VBN cord-015569-vy49r1zd 617 16 salivary salivary JJ cord-015569-vy49r1zd 617 17 secretions secretion NNS cord-015569-vy49r1zd 617 18 . . . cord-015569-vy49r1zd 618 1 This this DT cord-015569-vy49r1zd 618 2 suggests suggest VBZ cord-015569-vy49r1zd 618 3 that that IN cord-015569-vy49r1zd 618 4 , , , cord-015569-vy49r1zd 618 5 even even RB cord-015569-vy49r1zd 618 6 if if IN cord-015569-vy49r1zd 618 7 the the DT cord-015569-vy49r1zd 618 8 salivary salivary NN cord-015569-vy49r1zd 618 9 secretory secretory JJ cord-015569-vy49r1zd 618 10 function function NN cord-015569-vy49r1zd 618 11 is be VBZ cord-015569-vy49r1zd 618 12 maintained maintain VBN cord-015569-vy49r1zd 618 13 to to IN cord-015569-vy49r1zd 618 14 some some DT cord-015569-vy49r1zd 618 15 extent extent NN cord-015569-vy49r1zd 618 16 , , , cord-015569-vy49r1zd 618 17 the the DT cord-015569-vy49r1zd 618 18 sympathetic sympathetic JJ cord-015569-vy49r1zd 618 19 nerve nerve NN cord-015569-vy49r1zd 618 20 activity activity NN cord-015569-vy49r1zd 618 21 is be VBZ cord-015569-vy49r1zd 618 22 predominant predominant JJ cord-015569-vy49r1zd 618 23 due due IN cord-015569-vy49r1zd 618 24 to to IN cord-015569-vy49r1zd 618 25 tension tension NN cord-015569-vy49r1zd 618 26 . . . cord-015569-vy49r1zd 619 1 It -PRON- PRP cord-015569-vy49r1zd 619 2 is be VBZ cord-015569-vy49r1zd 619 3 necessary necessary JJ cord-015569-vy49r1zd 619 4 to to TO cord-015569-vy49r1zd 619 5 accumulate accumulate VB cord-015569-vy49r1zd 619 6 more more JJR cord-015569-vy49r1zd 619 7 clinical clinical JJ cord-015569-vy49r1zd 619 8 data datum NNS cord-015569-vy49r1zd 619 9 , , , cord-015569-vy49r1zd 619 10 such such JJ cord-015569-vy49r1zd 619 11 as as IN cord-015569-vy49r1zd 619 12 trigeminal trigeminal JJ cord-015569-vy49r1zd 619 13 sensitivity sensitivity NN cord-015569-vy49r1zd 619 14 of of IN cord-015569-vy49r1zd 619 15 the the DT cord-015569-vy49r1zd 619 16 tongue tongue NN cord-015569-vy49r1zd 619 17 in in IN cord-015569-vy49r1zd 619 18 comparison comparison NN cord-015569-vy49r1zd 619 19 with with IN cord-015569-vy49r1zd 619 20 the the DT cord-015569-vy49r1zd 619 21 electric electric JJ cord-015569-vy49r1zd 619 22 taste taste NN cord-015569-vy49r1zd 619 23 threshold threshold NN cord-015569-vy49r1zd 619 24 . . . cord-015569-vy49r1zd 620 1 Postoperative postoperative JJ cord-015569-vy49r1zd 620 2 oral oral JJ cord-015569-vy49r1zd 620 3 tumor tumor NN cord-015569-vy49r1zd 620 4 patients patient NNS cord-015569-vy49r1zd 620 5 show show VBP cord-015569-vy49r1zd 620 6 a a DT cord-015569-vy49r1zd 620 7 variety variety NN cord-015569-vy49r1zd 620 8 of of IN cord-015569-vy49r1zd 620 9 conditions condition NNS cord-015569-vy49r1zd 620 10 and and CC cord-015569-vy49r1zd 620 11 often often RB cord-015569-vy49r1zd 620 12 display display VBP cord-015569-vy49r1zd 620 13 taste taste NN cord-015569-vy49r1zd 620 14 dysfunction dysfunction NN cord-015569-vy49r1zd 620 15 resulting result VBG cord-015569-vy49r1zd 620 16 from from IN cord-015569-vy49r1zd 620 17 anti anti JJ cord-015569-vy49r1zd 620 18 - - JJ cord-015569-vy49r1zd 620 19 cancer cancer JJ cord-015569-vy49r1zd 620 20 drugs drug NNS cord-015569-vy49r1zd 620 21 , , , cord-015569-vy49r1zd 620 22 irradiation irradiation NN cord-015569-vy49r1zd 620 23 and and CC cord-015569-vy49r1zd 620 24 defects defect NNS cord-015569-vy49r1zd 620 25 of of IN cord-015569-vy49r1zd 620 26 oral oral JJ cord-015569-vy49r1zd 620 27 tissue tissue NN cord-015569-vy49r1zd 620 28 . . . cord-015569-vy49r1zd 621 1 Prosthetic prosthetic JJ cord-015569-vy49r1zd 621 2 rehabilitation rehabilitation NN cord-015569-vy49r1zd 621 3 should should MD cord-015569-vy49r1zd 621 4 be be VB cord-015569-vy49r1zd 621 5 required require VBN cord-015569-vy49r1zd 621 6 for for IN cord-015569-vy49r1zd 621 7 the the DT cord-015569-vy49r1zd 621 8 recovery recovery NN cord-015569-vy49r1zd 621 9 of of IN cord-015569-vy49r1zd 621 10 oral oral JJ cord-015569-vy49r1zd 621 11 functional functional JJ cord-015569-vy49r1zd 621 12 disorders disorder NNS cord-015569-vy49r1zd 621 13 . . . cord-015569-vy49r1zd 622 1 However however RB cord-015569-vy49r1zd 622 2 , , , cord-015569-vy49r1zd 622 3 no no DT cord-015569-vy49r1zd 622 4 reports report NNS cord-015569-vy49r1zd 622 5 have have VBP cord-015569-vy49r1zd 622 6 investigated investigate VBN cord-015569-vy49r1zd 622 7 taste taste NN cord-015569-vy49r1zd 622 8 disorder disorder NN cord-015569-vy49r1zd 622 9 for for IN cord-015569-vy49r1zd 622 10 patients patient NNS cord-015569-vy49r1zd 622 11 wearing wear VBG cord-015569-vy49r1zd 622 12 maxillofacial maxillofacial JJ cord-015569-vy49r1zd 622 13 prostheses prosthesis NNS cord-015569-vy49r1zd 622 14 . . . cord-015569-vy49r1zd 623 1 The the DT cord-015569-vy49r1zd 623 2 aim aim NN cord-015569-vy49r1zd 623 3 of of IN cord-015569-vy49r1zd 623 4 this this DT cord-015569-vy49r1zd 623 5 study study NN cord-015569-vy49r1zd 623 6 was be VBD cord-015569-vy49r1zd 623 7 to to TO cord-015569-vy49r1zd 623 8 clarify clarify VB cord-015569-vy49r1zd 623 9 taste taste NN cord-015569-vy49r1zd 623 10 sensation sensation NN cord-015569-vy49r1zd 623 11 in in IN cord-015569-vy49r1zd 623 12 postoperative postoperative JJ cord-015569-vy49r1zd 623 13 oral oral JJ cord-015569-vy49r1zd 623 14 tumor tumor NN cord-015569-vy49r1zd 623 15 patients patient NNS cord-015569-vy49r1zd 623 16 using use VBG cord-015569-vy49r1zd 623 17 the the DT cord-015569-vy49r1zd 623 18 filter filter NN cord-015569-vy49r1zd 623 19 - - HYPH cord-015569-vy49r1zd 623 20 paper paper NN cord-015569-vy49r1zd 623 21 disc disc NN cord-015569-vy49r1zd 623 22 method method NN cord-015569-vy49r1zd 623 23 , , , cord-015569-vy49r1zd 623 24 salivary salivary JJ cord-015569-vy49r1zd 623 25 secretions secretion NNS cord-015569-vy49r1zd 623 26 measured measure VBN cord-015569-vy49r1zd 623 27 by by IN cord-015569-vy49r1zd 623 28 gum gum NN cord-015569-vy49r1zd 623 29 chewing chewing NN cord-015569-vy49r1zd 623 30 , , , cord-015569-vy49r1zd 623 31 serum serum NN cord-015569-vy49r1zd 623 32 zinc zinc NN cord-015569-vy49r1zd 623 33 concentrations concentration NNS cord-015569-vy49r1zd 623 34 by by IN cord-015569-vy49r1zd 623 35 blood blood NN cord-015569-vy49r1zd 623 36 tests test NNS cord-015569-vy49r1zd 623 37 . . . cord-015569-vy49r1zd 624 1 We -PRON- PRP cord-015569-vy49r1zd 624 2 investigated investigate VBD cord-015569-vy49r1zd 624 3 patients patient NNS cord-015569-vy49r1zd 624 4 who who WP cord-015569-vy49r1zd 624 5 had have VBD cord-015569-vy49r1zd 624 6 undergone undergo VBN cord-015569-vy49r1zd 624 7 prosthodontic prosthodontic JJ cord-015569-vy49r1zd 624 8 treatment treatment NN cord-015569-vy49r1zd 624 9 in in IN cord-015569-vy49r1zd 624 10 the the DT cord-015569-vy49r1zd 624 11 Department Department NNP cord-015569-vy49r1zd 624 12 of of IN cord-015569-vy49r1zd 624 13 Prothodontics Prothodontics NNP cord-015569-vy49r1zd 624 14 and and CC cord-015569-vy49r1zd 624 15 Oral Oral NNP cord-015569-vy49r1zd 624 16 Rehabilitation Rehabilitation NNP cord-015569-vy49r1zd 624 17 at at IN cord-015569-vy49r1zd 624 18 Iwate Iwate NNP cord-015569-vy49r1zd 624 19 Medical Medical NNP cord-015569-vy49r1zd 624 20 University University NNP cord-015569-vy49r1zd 624 21 Dental Dental NNP cord-015569-vy49r1zd 624 22 Center Center NNP cord-015569-vy49r1zd 624 23 . . . cord-015569-vy49r1zd 625 1 Results result NNS cord-015569-vy49r1zd 625 2 were be VBD cord-015569-vy49r1zd 625 3 as as IN cord-015569-vy49r1zd 625 4 follows follow VBZ cord-015569-vy49r1zd 625 5 : : : cord-015569-vy49r1zd 626 1 1 1 LS cord-015569-vy49r1zd 626 2 ) ) -RRB- cord-015569-vy49r1zd 626 3 taste taste NN cord-015569-vy49r1zd 626 4 disorder disorder NN cord-015569-vy49r1zd 626 5 was be VBD cord-015569-vy49r1zd 626 6 seen see VBN cord-015569-vy49r1zd 626 7 in in IN cord-015569-vy49r1zd 626 8 90 90 CD cord-015569-vy49r1zd 626 9 % % NN cord-015569-vy49r1zd 626 10 of of IN cord-015569-vy49r1zd 626 11 cases case NNS cord-015569-vy49r1zd 626 12 ; ; : cord-015569-vy49r1zd 626 13 2 2 LS cord-015569-vy49r1zd 626 14 ) ) -RRB- cord-015569-vy49r1zd 626 15 within within IN cord-015569-vy49r1zd 626 16 2 2 CD cord-015569-vy49r1zd 626 17 years year NNS cord-015569-vy49r1zd 626 18 after after IN cord-015569-vy49r1zd 626 19 radiation radiation NN cord-015569-vy49r1zd 626 20 exposure exposure NN cord-015569-vy49r1zd 626 21 , , , cord-015569-vy49r1zd 626 22 the the DT cord-015569-vy49r1zd 626 23 degree degree NN cord-015569-vy49r1zd 626 24 of of IN cord-015569-vy49r1zd 626 25 taste taste NN cord-015569-vy49r1zd 626 26 disorder disorder NN cord-015569-vy49r1zd 626 27 was be VBD cord-015569-vy49r1zd 626 28 severe severe JJ cord-015569-vy49r1zd 626 29 ; ; : cord-015569-vy49r1zd 626 30 3 3 LS cord-015569-vy49r1zd 626 31 ) ) -RRB- cord-015569-vy49r1zd 626 32 disease disease NN cord-015569-vy49r1zd 626 33 severity severity NN cord-015569-vy49r1zd 626 34 did do VBD cord-015569-vy49r1zd 626 35 not not RB cord-015569-vy49r1zd 626 36 necessarily necessarily RB cord-015569-vy49r1zd 626 37 accord accord VB cord-015569-vy49r1zd 626 38 with with IN cord-015569-vy49r1zd 626 39 awareness awareness NN cord-015569-vy49r1zd 626 40 of of IN cord-015569-vy49r1zd 626 41 taste taste NN cord-015569-vy49r1zd 626 42 disorder disorder NN cord-015569-vy49r1zd 626 43 , , , cord-015569-vy49r1zd 626 44 and and CC cord-015569-vy49r1zd 626 45 some some DT cord-015569-vy49r1zd 626 46 patients patient NNS cord-015569-vy49r1zd 626 47 with with IN cord-015569-vy49r1zd 626 48 serious serious JJ cord-015569-vy49r1zd 626 49 taste taste NN cord-015569-vy49r1zd 626 50 decline decline NN cord-015569-vy49r1zd 626 51 were be VBD cord-015569-vy49r1zd 626 52 unaware unaware JJ cord-015569-vy49r1zd 626 53 of of IN cord-015569-vy49r1zd 626 54 their -PRON- PRP$ cord-015569-vy49r1zd 626 55 taste taste NN cord-015569-vy49r1zd 626 56 disorder disorder NN cord-015569-vy49r1zd 626 57 ; ; : cord-015569-vy49r1zd 626 58 and and CC cord-015569-vy49r1zd 626 59 4 4 LS cord-015569-vy49r1zd 626 60 ) ) -RRB- cord-015569-vy49r1zd 626 61 patients patient NNS cord-015569-vy49r1zd 626 62 who who WP cord-015569-vy49r1zd 626 63 were be VBD cord-015569-vy49r1zd 626 64 aware aware JJ cord-015569-vy49r1zd 626 65 of of IN cord-015569-vy49r1zd 626 66 their -PRON- PRP$ cord-015569-vy49r1zd 626 67 taste taste NN cord-015569-vy49r1zd 626 68 decline decline NN cord-015569-vy49r1zd 626 69 also also RB cord-015569-vy49r1zd 626 70 showed show VBD cord-015569-vy49r1zd 626 71 declines decline NNS cord-015569-vy49r1zd 626 72 in in IN cord-015569-vy49r1zd 626 73 chewing chewing NN cord-015569-vy49r1zd 626 74 score score NN cord-015569-vy49r1zd 626 75 . . . cord-015569-vy49r1zd 627 1 Objective objective JJ cord-015569-vy49r1zd 627 2 inspection inspection NN cord-015569-vy49r1zd 627 3 and and CC cord-015569-vy49r1zd 627 4 liaison liaison NN cord-015569-vy49r1zd 627 5 with with IN cord-015569-vy49r1zd 627 6 other other JJ cord-015569-vy49r1zd 627 7 departments department NNS cord-015569-vy49r1zd 627 8 to to TO cord-015569-vy49r1zd 627 9 include include VB cord-015569-vy49r1zd 627 10 an an DT cord-015569-vy49r1zd 627 11 otolaryngologist otolaryngologist NN cord-015569-vy49r1zd 627 12 , , , cord-015569-vy49r1zd 627 13 doctor doctor NN cord-015569-vy49r1zd 627 14 of of IN cord-015569-vy49r1zd 627 15 psychosomatic psychosomatic JJ cord-015569-vy49r1zd 627 16 medicine medicine NN cord-015569-vy49r1zd 627 17 , , , cord-015569-vy49r1zd 627 18 and and CC cord-015569-vy49r1zd 627 19 a a DT cord-015569-vy49r1zd 627 20 dietitian dietitian NN cord-015569-vy49r1zd 627 21 is be VBZ cord-015569-vy49r1zd 627 22 important important JJ cord-015569-vy49r1zd 627 23 . . . cord-015569-vy49r1zd 628 1 It -PRON- PRP cord-015569-vy49r1zd 628 2 is be VBZ cord-015569-vy49r1zd 628 3 known know VBN cord-015569-vy49r1zd 628 4 that that IN cord-015569-vy49r1zd 628 5 more more JJR cord-015569-vy49r1zd 628 6 than than IN cord-015569-vy49r1zd 628 7 70 70 CD cord-015569-vy49r1zd 628 8 % % NN cord-015569-vy49r1zd 628 9 of of IN cord-015569-vy49r1zd 628 10 patients patient NNS cord-015569-vy49r1zd 628 11 with with IN cord-015569-vy49r1zd 628 12 taste taste NN cord-015569-vy49r1zd 628 13 dysfunction dysfunction NN cord-015569-vy49r1zd 628 14 have have VBP cord-015569-vy49r1zd 628 15 zinc zinc NN cord-015569-vy49r1zd 628 16 deficiency deficiency NN cord-015569-vy49r1zd 628 17 . . . cord-015569-vy49r1zd 629 1 Carbonic carbonic JJ cord-015569-vy49r1zd 629 2 anhydrase anhydrase NN cord-015569-vy49r1zd 629 3 ( ( -LRB- cord-015569-vy49r1zd 629 4 CA CA NNP cord-015569-vy49r1zd 629 5 ) ) -RRB- cord-015569-vy49r1zd 629 6 VI VI NNP cord-015569-vy49r1zd 629 7 , , , cord-015569-vy49r1zd 629 8 also also RB cord-015569-vy49r1zd 629 9 known know VBN cord-015569-vy49r1zd 629 10 as as IN cord-015569-vy49r1zd 629 11 gustin gustin NNP cord-015569-vy49r1zd 629 12 , , , cord-015569-vy49r1zd 629 13 is be VBZ cord-015569-vy49r1zd 629 14 a a DT cord-015569-vy49r1zd 629 15 37,000-Da 37,000-da CD cord-015569-vy49r1zd 629 16 zinc zinc NN cord-015569-vy49r1zd 629 17 metallo metallo NN cord-015569-vy49r1zd 629 18 - - HYPH cord-015569-vy49r1zd 629 19 protein protein NN cord-015569-vy49r1zd 629 20 found find VBN cord-015569-vy49r1zd 629 21 in in IN cord-015569-vy49r1zd 629 22 human human JJ cord-015569-vy49r1zd 629 23 saliva saliva NN cord-015569-vy49r1zd 629 24 and and CC cord-015569-vy49r1zd 629 25 is be VBZ cord-015569-vy49r1zd 629 26 involved involve VBN cord-015569-vy49r1zd 629 27 in in IN cord-015569-vy49r1zd 629 28 taste taste NN cord-015569-vy49r1zd 629 29 dysfunction dysfunction NN cord-015569-vy49r1zd 629 30 . . . cord-015569-vy49r1zd 630 1 It -PRON- PRP cord-015569-vy49r1zd 630 2 can can MD cord-015569-vy49r1zd 630 3 be be VB cord-015569-vy49r1zd 630 4 detected detect VBN cord-015569-vy49r1zd 630 5 by by IN cord-015569-vy49r1zd 630 6 enzymelinked enzymelinked JJ cord-015569-vy49r1zd 630 7 immunosorbent immunosorbent JJ cord-015569-vy49r1zd 630 8 assay assay NN cord-015569-vy49r1zd 630 9 , , , cord-015569-vy49r1zd 630 10 but but CC cord-015569-vy49r1zd 630 11 the the DT cord-015569-vy49r1zd 630 12 test test NN cord-015569-vy49r1zd 630 13 takes take VBZ cord-015569-vy49r1zd 630 14 time time NN cord-015569-vy49r1zd 630 15 . . . cord-015569-vy49r1zd 631 1 Therefore therefore RB cord-015569-vy49r1zd 631 2 , , , cord-015569-vy49r1zd 631 3 in in IN cord-015569-vy49r1zd 631 4 this this DT cord-015569-vy49r1zd 631 5 study study NN cord-015569-vy49r1zd 631 6 , , , cord-015569-vy49r1zd 631 7 we -PRON- PRP cord-015569-vy49r1zd 631 8 developed develop VBD cord-015569-vy49r1zd 631 9 a a DT cord-015569-vy49r1zd 631 10 new new JJ cord-015569-vy49r1zd 631 11 quick quick JJ cord-015569-vy49r1zd 631 12 and and CC cord-015569-vy49r1zd 631 13 simple simple JJ cord-015569-vy49r1zd 631 14 method method NN cord-015569-vy49r1zd 631 15 of of IN cord-015569-vy49r1zd 631 16 diagnosis diagnosis NN cord-015569-vy49r1zd 631 17 using use VBG cord-015569-vy49r1zd 631 18 an an DT cord-015569-vy49r1zd 631 19 immunochromatography immunochromatography NN cord-015569-vy49r1zd 631 20 assay assay NN cord-015569-vy49r1zd 631 21 to to TO cord-015569-vy49r1zd 631 22 be be VB cord-015569-vy49r1zd 631 23 used use VBN cord-015569-vy49r1zd 631 24 as as IN cord-015569-vy49r1zd 631 25 an an DT cord-015569-vy49r1zd 631 26 on on IN cord-015569-vy49r1zd 631 27 - - HYPH cord-015569-vy49r1zd 631 28 site site NN cord-015569-vy49r1zd 631 29 test test NN cord-015569-vy49r1zd 631 30 . . . cord-015569-vy49r1zd 632 1 First first RB cord-015569-vy49r1zd 632 2 , , , cord-015569-vy49r1zd 632 3 reactivity reactivity NN cord-015569-vy49r1zd 632 4 with with IN cord-015569-vy49r1zd 632 5 a a DT cord-015569-vy49r1zd 632 6 serum serum NN cord-015569-vy49r1zd 632 7 antibody antibody NN cord-015569-vy49r1zd 632 8 ( ( -LRB- cord-015569-vy49r1zd 632 9 prepared prepare VBN cord-015569-vy49r1zd 632 10 using use VBG cord-015569-vy49r1zd 632 11 a a DT cord-015569-vy49r1zd 632 12 synthetic synthetic JJ cord-015569-vy49r1zd 632 13 peptide peptide NN cord-015569-vy49r1zd 632 14 designed design VBN cord-015569-vy49r1zd 632 15 from from IN cord-015569-vy49r1zd 632 16 a a DT cord-015569-vy49r1zd 632 17 93 93 CD cord-015569-vy49r1zd 632 18 - - SYM cord-015569-vy49r1zd 632 19 111 111 CD cord-015569-vy49r1zd 632 20 amino amino NN cord-015569-vy49r1zd 632 21 acid acid NN cord-015569-vy49r1zd 632 22 chain chain NN cord-015569-vy49r1zd 632 23 of of IN cord-015569-vy49r1zd 632 24 human human JJ cord-015569-vy49r1zd 632 25 CA CA NNP cord-015569-vy49r1zd 632 26 VI VI NNP cord-015569-vy49r1zd 632 27 as as IN cord-015569-vy49r1zd 632 28 a a DT cord-015569-vy49r1zd 632 29 hapten hapten NN cord-015569-vy49r1zd 632 30 conjugated conjugate VBN cord-015569-vy49r1zd 632 31 to to TO cord-015569-vy49r1zd 632 32 keyhole keyhole VB cord-015569-vy49r1zd 632 33 limpet limpet NNP cord-015569-vy49r1zd 632 34 hemocyanin hemocyanin NN cord-015569-vy49r1zd 632 35 and and CC cord-015569-vy49r1zd 632 36 injected inject VBD cord-015569-vy49r1zd 632 37 into into IN cord-015569-vy49r1zd 632 38 two two CD cord-015569-vy49r1zd 632 39 New New NNP cord-015569-vy49r1zd 632 40 Zealand Zealand NNP cord-015569-vy49r1zd 632 41 white white JJ cord-015569-vy49r1zd 632 42 rabbits rabbit NNS cord-015569-vy49r1zd 632 43 ) ) -RRB- cord-015569-vy49r1zd 632 44 was be VBD cord-015569-vy49r1zd 632 45 evaluated evaluate VBN cord-015569-vy49r1zd 632 46 and and CC cord-015569-vy49r1zd 632 47 compared compare VBN cord-015569-vy49r1zd 632 48 to to IN cord-015569-vy49r1zd 632 49 a a DT cord-015569-vy49r1zd 632 50 control control NN cord-015569-vy49r1zd 632 51 ( ( -LRB- cord-015569-vy49r1zd 632 52 swine swine NNP cord-015569-vy49r1zd 632 53 antirabbit antirabbit NNP cord-015569-vy49r1zd 632 54 IgG IgG NNP cord-015569-vy49r1zd 632 55 ) ) -RRB- cord-015569-vy49r1zd 632 56 using use VBG cord-015569-vy49r1zd 632 57 a a DT cord-015569-vy49r1zd 632 58 Hi hi JJ cord-015569-vy49r1zd 632 59 - - HYPH cord-015569-vy49r1zd 632 60 flow flow NN cord-015569-vy49r1zd 632 61 plus120 plus120 NN cord-015569-vy49r1zd 632 62 membrane membrane NN cord-015569-vy49r1zd 632 63 and and CC cord-015569-vy49r1zd 632 64 detected detect VBN cord-015569-vy49r1zd 632 65 with with IN cord-015569-vy49r1zd 632 66 colloidal colloidal JJ cord-015569-vy49r1zd 632 67 gold gold NN cord-015569-vy49r1zd 632 68 . . . cord-015569-vy49r1zd 633 1 A a DT cord-015569-vy49r1zd 633 2 difference difference NN cord-015569-vy49r1zd 633 3 in in IN cord-015569-vy49r1zd 633 4 color color NN cord-015569-vy49r1zd 633 5 development development NN cord-015569-vy49r1zd 633 6 was be VBD cord-015569-vy49r1zd 633 7 observed observe VBN cord-015569-vy49r1zd 633 8 between between IN cord-015569-vy49r1zd 633 9 samples sample NNS cord-015569-vy49r1zd 633 10 of of IN cord-015569-vy49r1zd 633 11 PBS PBS NNP cord-015569-vy49r1zd 633 12 ( ( -LRB- cord-015569-vy49r1zd 633 13 - - : cord-015569-vy49r1zd 633 14 ) ) -RRB- cord-015569-vy49r1zd 633 15 and and CC cord-015569-vy49r1zd 633 16 the the DT cord-015569-vy49r1zd 633 17 positive positive JJ cord-015569-vy49r1zd 633 18 control control NN cord-015569-vy49r1zd 633 19 ( ( -LRB- cord-015569-vy49r1zd 633 20 synthetic synthetic JJ cord-015569-vy49r1zd 633 21 peptide peptide NN cord-015569-vy49r1zd 633 22 ) ) -RRB- cord-015569-vy49r1zd 633 23 . . . cord-015569-vy49r1zd 634 1 Furthermore furthermore RB cord-015569-vy49r1zd 634 2 , , , cord-015569-vy49r1zd 634 3 it -PRON- PRP cord-015569-vy49r1zd 634 4 was be VBD cord-015569-vy49r1zd 634 5 density density NN cord-015569-vy49r1zd 634 6 dependent dependent JJ cord-015569-vy49r1zd 634 7 , , , cord-015569-vy49r1zd 634 8 and and CC cord-015569-vy49r1zd 634 9 in in IN cord-015569-vy49r1zd 634 10 serially serially RB cord-015569-vy49r1zd 634 11 diluted dilute VBN cord-015569-vy49r1zd 634 12 parotid parotid JJ cord-015569-vy49r1zd 634 13 gland gland NN cord-015569-vy49r1zd 634 14 saliva saliva NN cord-015569-vy49r1zd 634 15 , , , cord-015569-vy49r1zd 634 16 the the DT cord-015569-vy49r1zd 634 17 color color NN cord-015569-vy49r1zd 634 18 development development NN cord-015569-vy49r1zd 634 19 was be VBD cord-015569-vy49r1zd 634 20 seen see VBN cord-015569-vy49r1zd 634 21 to to TO cord-015569-vy49r1zd 634 22 be be VB cord-015569-vy49r1zd 634 23 640 640 CD cord-015569-vy49r1zd 634 24 times time NNS cord-015569-vy49r1zd 634 25 dilution dilution NN cord-015569-vy49r1zd 634 26 density density NN cord-015569-vy49r1zd 634 27 from from IN cord-015569-vy49r1zd 634 28 8 8 CD cord-015569-vy49r1zd 634 29 times time NNS cord-015569-vy49r1zd 634 30 dilution dilution NN cord-015569-vy49r1zd 634 31 density density NN cord-015569-vy49r1zd 634 32 . . . cord-015569-vy49r1zd 635 1 The the DT cord-015569-vy49r1zd 635 2 results result NNS cord-015569-vy49r1zd 635 3 suggest suggest VBP cord-015569-vy49r1zd 635 4 that that IN cord-015569-vy49r1zd 635 5 an an DT cord-015569-vy49r1zd 635 6 immunochromatography immunochromatography NN cord-015569-vy49r1zd 635 7 assay assay NN cord-015569-vy49r1zd 635 8 using use VBG cord-015569-vy49r1zd 635 9 this this DT cord-015569-vy49r1zd 635 10 novel novel JJ cord-015569-vy49r1zd 635 11 antibody antibody NN cord-015569-vy49r1zd 635 12 can can MD cord-015569-vy49r1zd 635 13 be be VB cord-015569-vy49r1zd 635 14 used use VBN cord-015569-vy49r1zd 635 15 to to TO cord-015569-vy49r1zd 635 16 quantitatively quantitatively RB cord-015569-vy49r1zd 635 17 measure measure VB cord-015569-vy49r1zd 635 18 CA CA NNP cord-015569-vy49r1zd 635 19 VI VI NNP cord-015569-vy49r1zd 635 20 , , , cord-015569-vy49r1zd 635 21 which which WDT cord-015569-vy49r1zd 635 22 may may MD cord-015569-vy49r1zd 635 23 be be VB cord-015569-vy49r1zd 635 24 useful useful JJ cord-015569-vy49r1zd 635 25 in in IN cord-015569-vy49r1zd 635 26 the the DT cord-015569-vy49r1zd 635 27 diagnosis diagnosis NN cord-015569-vy49r1zd 635 28 of of IN cord-015569-vy49r1zd 635 29 taste taste NN cord-015569-vy49r1zd 635 30 dysfunction dysfunction NN cord-015569-vy49r1zd 635 31 caused cause VBN cord-015569-vy49r1zd 635 32 by by IN cord-015569-vy49r1zd 635 33 zinc zinc NN cord-015569-vy49r1zd 635 34 deficiency deficiency NN cord-015569-vy49r1zd 635 35 . . . cord-015569-vy49r1zd 636 1 # # $ cord-015569-vy49r1zd 636 2 58 58 CD cord-015569-vy49r1zd 636 3 The the DT cord-015569-vy49r1zd 636 4 epithelium epithelium NN cord-015569-vy49r1zd 636 5 of of IN cord-015569-vy49r1zd 636 6 recessus recessus NN cord-015569-vy49r1zd 636 7 olfactorius olfactorius NNP cord-015569-vy49r1zd 636 8 is be VBZ cord-015569-vy49r1zd 636 9 a a DT cord-015569-vy49r1zd 636 10 part part NN cord-015569-vy49r1zd 636 11 of of IN cord-015569-vy49r1zd 636 12 the the DT cord-015569-vy49r1zd 636 13 accessory accessory JJ cord-015569-vy49r1zd 636 14 olfactory olfactory JJ cord-015569-vy49r1zd 636 15 system system NN cord-015569-vy49r1zd 636 16 in in IN cord-015569-vy49r1zd 636 17 the the DT cord-015569-vy49r1zd 636 18 Japanese japanese JJ cord-015569-vy49r1zd 636 19 toad toad NN cord-015569-vy49r1zd 636 20 ( ( -LRB- cord-015569-vy49r1zd 636 21 Bufo Bufo NNP cord-015569-vy49r1zd 636 22 japonicus japonicus NN cord-015569-vy49r1zd 636 23 ) ) -RRB- cord-015569-vy49r1zd 637 1 Hideo Hideo NNP cord-015569-vy49r1zd 637 2 Nakazawa Nakazawa NNP cord-015569-vy49r1zd 637 3 1 1 CD cord-015569-vy49r1zd 637 4 , , , cord-015569-vy49r1zd 637 5 Kimiko Kimiko NNP cord-015569-vy49r1zd 637 6 Hagino Hagino NNP cord-015569-vy49r1zd 637 7 - - HYPH cord-015569-vy49r1zd 637 8 Yamagishi Yamagishi NNP cord-015569-vy49r1zd 637 9 2 2 CD cord-015569-vy49r1zd 637 10 , , , cord-015569-vy49r1zd 637 11 Atsushi Atsushi NNP cord-015569-vy49r1zd 637 12 C. C. NNP cord-015569-vy49r1zd 637 13 Suzuki Suzuki NNP cord-015569-vy49r1zd 637 14 1 1 CD cord-015569-vy49r1zd 637 15 and and CC cord-015569-vy49r1zd 637 16 Takatoshi Takatoshi NNP cord-015569-vy49r1zd 637 17 Nagai Nagai NNP cord-015569-vy49r1zd 637 18 1 1 CD cord-015569-vy49r1zd 638 1 The the DT cord-015569-vy49r1zd 638 2 recessus recessus NN cord-015569-vy49r1zd 638 3 olfactorius olfactorius NN cord-015569-vy49r1zd 638 4 ( ( -LRB- cord-015569-vy49r1zd 638 5 RO RO NNP cord-015569-vy49r1zd 638 6 ) ) -RRB- cord-015569-vy49r1zd 638 7 is be VBZ cord-015569-vy49r1zd 638 8 a a DT cord-015569-vy49r1zd 638 9 small small JJ cord-015569-vy49r1zd 638 10 pouch pouch NN cord-015569-vy49r1zd 638 11 observed observe VBN cord-015569-vy49r1zd 638 12 in in IN cord-015569-vy49r1zd 638 13 the the DT cord-015569-vy49r1zd 638 14 antero antero NNP cord-015569-vy49r1zd 638 15 - - HYPH cord-015569-vy49r1zd 638 16 lateral lateral JJ cord-015569-vy49r1zd 638 17 olfactory olfactory JJ cord-015569-vy49r1zd 638 18 epithelium epithelium NN cord-015569-vy49r1zd 638 19 of of IN cord-015569-vy49r1zd 638 20 anurans anuran NNS cord-015569-vy49r1zd 638 21 . . . cord-015569-vy49r1zd 639 1 RO RO NNP cord-015569-vy49r1zd 639 2 is be VBZ cord-015569-vy49r1zd 639 3 mostly mostly RB cord-015569-vy49r1zd 639 4 covered cover VBN cord-015569-vy49r1zd 639 5 with with IN cord-015569-vy49r1zd 639 6 the the DT cord-015569-vy49r1zd 639 7 epithelial epithelial JJ cord-015569-vy49r1zd 639 8 cells cell NNS cord-015569-vy49r1zd 639 9 with with IN cord-015569-vy49r1zd 639 10 cilia cilium NNS cord-015569-vy49r1zd 639 11 , , , cord-015569-vy49r1zd 639 12 which which WDT cord-015569-vy49r1zd 639 13 is be VBZ cord-015569-vy49r1zd 639 14 reminiscent reminiscent JJ cord-015569-vy49r1zd 639 15 of of IN cord-015569-vy49r1zd 639 16 sensory sensory JJ cord-015569-vy49r1zd 639 17 function function NN cord-015569-vy49r1zd 639 18 . . . cord-015569-vy49r1zd 640 1 However however RB cord-015569-vy49r1zd 640 2 , , , cord-015569-vy49r1zd 640 3 if if IN cord-015569-vy49r1zd 640 4 RO RO NNP cord-015569-vy49r1zd 640 5 is be VBZ cord-015569-vy49r1zd 640 6 a a DT cord-015569-vy49r1zd 640 7 part part NN cord-015569-vy49r1zd 640 8 of of IN cord-015569-vy49r1zd 640 9 the the DT cord-015569-vy49r1zd 640 10 main main JJ cord-015569-vy49r1zd 640 11 olfactory olfactory JJ cord-015569-vy49r1zd 640 12 system system NN cord-015569-vy49r1zd 640 13 has have VBZ cord-015569-vy49r1zd 640 14 not not RB cord-015569-vy49r1zd 640 15 been be VBN cord-015569-vy49r1zd 640 16 studied study VBN cord-015569-vy49r1zd 640 17 . . . cord-015569-vy49r1zd 641 1 We -PRON- PRP cord-015569-vy49r1zd 641 2 studied study VBD cord-015569-vy49r1zd 641 3 the the DT cord-015569-vy49r1zd 641 4 epithelium epithelium NN cord-015569-vy49r1zd 641 5 of of IN cord-015569-vy49r1zd 641 6 RO ro NN cord-015569-vy49r1zd 641 7 ( ( -LRB- cord-015569-vy49r1zd 641 8 RO ro NN cord-015569-vy49r1zd 641 9 epithelium epithelium NN cord-015569-vy49r1zd 641 10 ) ) -RRB- cord-015569-vy49r1zd 641 11 in in IN cord-015569-vy49r1zd 641 12 Japanese japanese JJ cord-015569-vy49r1zd 641 13 toads toad NNS cord-015569-vy49r1zd 641 14 regarding regard VBG cord-015569-vy49r1zd 641 15 central central JJ cord-015569-vy49r1zd 641 16 projection projection NN cord-015569-vy49r1zd 641 17 , , , cord-015569-vy49r1zd 641 18 ultrastructure ultrastructure NN cord-015569-vy49r1zd 641 19 and and CC cord-015569-vy49r1zd 641 20 expression expression NN cord-015569-vy49r1zd 641 21 of of IN cord-015569-vy49r1zd 641 22 proteins protein NNS cord-015569-vy49r1zd 641 23 involved involve VBN cord-015569-vy49r1zd 641 24 in in IN cord-015569-vy49r1zd 641 25 olfactory olfactory JJ cord-015569-vy49r1zd 641 26 transduction transduction NN cord-015569-vy49r1zd 641 27 . . . cord-015569-vy49r1zd 642 1 Fluorescent fluorescent JJ cord-015569-vy49r1zd 642 2 carbocyanine carbocyanine JJ cord-015569-vy49r1zd 642 3 dye dye NN cord-015569-vy49r1zd 642 4 ( ( -LRB- cord-015569-vy49r1zd 642 5 diI diI NNP cord-015569-vy49r1zd 642 6 ) ) -RRB- cord-015569-vy49r1zd 642 7 was be VBD cord-015569-vy49r1zd 642 8 placed place VBN cord-015569-vy49r1zd 642 9 on on IN cord-015569-vy49r1zd 642 10 the the DT cord-015569-vy49r1zd 642 11 RO ro NN cord-015569-vy49r1zd 642 12 epithelium epithelium NN cord-015569-vy49r1zd 642 13 to to TO cord-015569-vy49r1zd 642 14 show show VB cord-015569-vy49r1zd 642 15 a a DT cord-015569-vy49r1zd 642 16 neuronal neuronal JJ cord-015569-vy49r1zd 642 17 projection projection NN cord-015569-vy49r1zd 642 18 from from IN cord-015569-vy49r1zd 642 19 RO RO NNP cord-015569-vy49r1zd 642 20 . . . cord-015569-vy49r1zd 643 1 Fluorescent fluorescent JJ cord-015569-vy49r1zd 643 2 signal signal NN cord-015569-vy49r1zd 643 3 was be VBD cord-015569-vy49r1zd 643 4 not not RB cord-015569-vy49r1zd 643 5 detected detect VBN cord-015569-vy49r1zd 643 6 in in IN cord-015569-vy49r1zd 643 7 the the DT cord-015569-vy49r1zd 643 8 main main JJ cord-015569-vy49r1zd 643 9 olfactory olfactory JJ cord-015569-vy49r1zd 643 10 bulb bulb NN cord-015569-vy49r1zd 643 11 , , , cord-015569-vy49r1zd 643 12 but but CC cord-015569-vy49r1zd 643 13 in in IN cord-015569-vy49r1zd 643 14 the the DT cord-015569-vy49r1zd 643 15 accessory accessory JJ cord-015569-vy49r1zd 643 16 olfactory olfactory JJ cord-015569-vy49r1zd 643 17 bulb bulb NN cord-015569-vy49r1zd 643 18 . . . cord-015569-vy49r1zd 644 1 In in IN cord-015569-vy49r1zd 644 2 contrast contrast NN cord-015569-vy49r1zd 644 3 to to IN cord-015569-vy49r1zd 644 4 the the DT cord-015569-vy49r1zd 644 5 olfactory olfactory JJ cord-015569-vy49r1zd 644 6 epithelium epithelium NN cord-015569-vy49r1zd 644 7 which which WDT cord-015569-vy49r1zd 644 8 does do VBZ cord-015569-vy49r1zd 644 9 not not RB cord-015569-vy49r1zd 644 10 contain contain VB cord-015569-vy49r1zd 644 11 microvillous microvillous JJ cord-015569-vy49r1zd 644 12 receptor receptor NN cord-015569-vy49r1zd 644 13 cells cell NNS cord-015569-vy49r1zd 644 14 , , , cord-015569-vy49r1zd 644 15 the the DT cord-015569-vy49r1zd 644 16 RO ro NN cord-015569-vy49r1zd 644 17 epithelium epithelium NN cord-015569-vy49r1zd 644 18 contained contain VBD cord-015569-vy49r1zd 644 19 both both DT cord-015569-vy49r1zd 644 20 ciliated ciliated JJ cord-015569-vy49r1zd 644 21 cells cell NNS cord-015569-vy49r1zd 644 22 and and CC cord-015569-vy49r1zd 644 23 micro micro JJ cord-015569-vy49r1zd 644 24 - - JJ cord-015569-vy49r1zd 644 25 villous villous JJ cord-015569-vy49r1zd 644 26 cells cell NNS cord-015569-vy49r1zd 644 27 . . . cord-015569-vy49r1zd 645 1 The the DT cord-015569-vy49r1zd 645 2 expression expression NN cord-015569-vy49r1zd 645 3 of of IN cord-015569-vy49r1zd 645 4 a a DT cord-015569-vy49r1zd 645 5 - - HYPH cord-015569-vy49r1zd 645 6 subunit subunit NN cord-015569-vy49r1zd 645 7 of of IN cord-015569-vy49r1zd 645 8 G g NN cord-015569-vy49r1zd 645 9 - - HYPH cord-015569-vy49r1zd 645 10 proteins protein NNS cord-015569-vy49r1zd 645 11 ( ( -LRB- cord-015569-vy49r1zd 645 12 G g NN cord-015569-vy49r1zd 645 13 aolf aolf NN cord-015569-vy49r1zd 645 14 and and CC cord-015569-vy49r1zd 645 15 G G NNP cord-015569-vy49r1zd 645 16 ao ao NN cord-015569-vy49r1zd 645 17 ) ) -RRB- cord-015569-vy49r1zd 645 18 in in IN cord-015569-vy49r1zd 645 19 the the DT cord-015569-vy49r1zd 645 20 RO RO NNP cord-015569-vy49r1zd 645 21 epithelium epithelium NN cord-015569-vy49r1zd 645 22 was be VBD cord-015569-vy49r1zd 645 23 examined examine VBN cord-015569-vy49r1zd 645 24 by by IN cord-015569-vy49r1zd 645 25 immunohistochemistry immunohistochemistry NN cord-015569-vy49r1zd 645 26 and and CC cord-015569-vy49r1zd 645 27 in in IN cord-015569-vy49r1zd 645 28 situ situ JJ cord-015569-vy49r1zd 645 29 hybridization hybridization NN cord-015569-vy49r1zd 645 30 . . . cord-015569-vy49r1zd 646 1 Regionally regionally RB cord-015569-vy49r1zd 646 2 different different JJ cord-015569-vy49r1zd 646 3 expression expression NN cord-015569-vy49r1zd 646 4 of of IN cord-015569-vy49r1zd 646 5 G g NN cord-015569-vy49r1zd 646 6 aolf aolf NN cord-015569-vy49r1zd 646 7 and and CC cord-015569-vy49r1zd 646 8 G G NNP cord-015569-vy49r1zd 646 9 ao ao NN cord-015569-vy49r1zd 646 10 was be VBD cord-015569-vy49r1zd 646 11 detected detect VBN cord-015569-vy49r1zd 646 12 in in IN cord-015569-vy49r1zd 646 13 the the DT cord-015569-vy49r1zd 646 14 RO ro NN cord-015569-vy49r1zd 646 15 epithelium epithelium NN cord-015569-vy49r1zd 646 16 , , , cord-015569-vy49r1zd 646 17 namely namely RB cord-015569-vy49r1zd 646 18 expression expression NN cord-015569-vy49r1zd 646 19 of of IN cord-015569-vy49r1zd 646 20 G g NN cord-015569-vy49r1zd 646 21 aolf aolf NN cord-015569-vy49r1zd 646 22 in in IN cord-015569-vy49r1zd 646 23 the the DT cord-015569-vy49r1zd 646 24 apical apical JJ cord-015569-vy49r1zd 646 25 cell cell NN cord-015569-vy49r1zd 646 26 layer layer NN cord-015569-vy49r1zd 646 27 and and CC cord-015569-vy49r1zd 646 28 G G NNP cord-015569-vy49r1zd 646 29 ao ao NN cord-015569-vy49r1zd 646 30 in in IN cord-015569-vy49r1zd 646 31 the the DT cord-015569-vy49r1zd 646 32 basal basal NN cord-015569-vy49r1zd 646 33 cell cell NN cord-015569-vy49r1zd 646 34 layer layer NN cord-015569-vy49r1zd 646 35 . . . cord-015569-vy49r1zd 647 1 Such such JJ cord-015569-vy49r1zd 647 2 a a DT cord-015569-vy49r1zd 647 3 pattern pattern NN cord-015569-vy49r1zd 647 4 of of IN cord-015569-vy49r1zd 647 5 G g NN cord-015569-vy49r1zd 647 6 - - HYPH cord-015569-vy49r1zd 647 7 protein protein NN cord-015569-vy49r1zd 647 8 expression expression NN cord-015569-vy49r1zd 647 9 in in IN cord-015569-vy49r1zd 647 10 the the DT cord-015569-vy49r1zd 647 11 RO ro NN cord-015569-vy49r1zd 647 12 epithelium epithelium NN cord-015569-vy49r1zd 647 13 was be VBD cord-015569-vy49r1zd 647 14 similar similar JJ cord-015569-vy49r1zd 647 15 to to IN cord-015569-vy49r1zd 647 16 that that DT cord-015569-vy49r1zd 647 17 in in IN cord-015569-vy49r1zd 647 18 the the DT cord-015569-vy49r1zd 647 19 vomeronasal vomeronasal NN cord-015569-vy49r1zd 647 20 epithelium epithelium NN cord-015569-vy49r1zd 647 21 . . . cord-015569-vy49r1zd 648 1 These these DT cord-015569-vy49r1zd 648 2 results result NNS cord-015569-vy49r1zd 648 3 suggest suggest VBP cord-015569-vy49r1zd 648 4 that that IN cord-015569-vy49r1zd 648 5 the the DT cord-015569-vy49r1zd 648 6 RO ro NN cord-015569-vy49r1zd 648 7 epithelium epithelium NN cord-015569-vy49r1zd 648 8 belongs belong VBZ cord-015569-vy49r1zd 648 9 to to IN cord-015569-vy49r1zd 648 10 the the DT cord-015569-vy49r1zd 648 11 accessory accessory JJ cord-015569-vy49r1zd 648 12 olfactory olfactory JJ cord-015569-vy49r1zd 648 13 system system NN cord-015569-vy49r1zd 648 14 . . . cord-015569-vy49r1zd 649 1 However however RB cord-015569-vy49r1zd 649 2 , , , cord-015569-vy49r1zd 649 3 the the DT cord-015569-vy49r1zd 649 4 RO ro NN cord-015569-vy49r1zd 649 5 epithelium epithelium NN cord-015569-vy49r1zd 649 6 contained contain VBD cord-015569-vy49r1zd 649 7 secretory secretory JJ cord-015569-vy49r1zd 649 8 cells cell NNS cord-015569-vy49r1zd 649 9 with with IN cord-015569-vy49r1zd 649 10 granules granule NNS cord-015569-vy49r1zd 649 11 that that WDT cord-015569-vy49r1zd 649 12 were be VBD cord-015569-vy49r1zd 649 13 not not RB cord-015569-vy49r1zd 649 14 contained contain VBN cord-015569-vy49r1zd 649 15 in in IN cord-015569-vy49r1zd 649 16 the the DT cord-015569-vy49r1zd 649 17 vomeronasal vomeronasal NN cord-015569-vy49r1zd 649 18 epithelium epithelium NN cord-015569-vy49r1zd 649 19 . . . cord-015569-vy49r1zd 650 1 Physiological physiological JJ cord-015569-vy49r1zd 650 2 experiments experiment NNS cord-015569-vy49r1zd 650 3 will will MD cord-015569-vy49r1zd 650 4 further further RB cord-015569-vy49r1zd 650 5 clarify clarify VB cord-015569-vy49r1zd 650 6 if if IN cord-015569-vy49r1zd 650 7 the the DT cord-015569-vy49r1zd 650 8 RO ro NN cord-015569-vy49r1zd 650 9 epithelium epithelium NN cord-015569-vy49r1zd 650 10 is be VBZ cord-015569-vy49r1zd 650 11 functionally functionally RB cord-015569-vy49r1zd 650 12 similar similar JJ cord-015569-vy49r1zd 650 13 to to IN cord-015569-vy49r1zd 650 14 the the DT cord-015569-vy49r1zd 650 15 vomeronasal vomeronasal NN cord-015569-vy49r1zd 650 16 epithelium epithelium NN cord-015569-vy49r1zd 650 17 . . . cord-015569-vy49r1zd 651 1 In in IN cord-015569-vy49r1zd 651 2 mice mouse NNS cord-015569-vy49r1zd 651 3 , , , cord-015569-vy49r1zd 651 4 the the DT cord-015569-vy49r1zd 651 5 female female NN cord-015569-vy49r1zd 651 6 memorizes memorize VBZ cord-015569-vy49r1zd 651 7 some some DT cord-015569-vy49r1zd 651 8 urinary urinary JJ cord-015569-vy49r1zd 651 9 pheromones pheromone NNS cord-015569-vy49r1zd 651 10 of of IN cord-015569-vy49r1zd 651 11 the the DT cord-015569-vy49r1zd 651 12 mating mating NN cord-015569-vy49r1zd 651 13 male male NN cord-015569-vy49r1zd 651 14 , , , cord-015569-vy49r1zd 651 15 thereby thereby RB cord-015569-vy49r1zd 651 16 preventing prevent VBG cord-015569-vy49r1zd 651 17 the the DT cord-015569-vy49r1zd 651 18 pheromones pheromone NNS cord-015569-vy49r1zd 651 19 from from IN cord-015569-vy49r1zd 651 20 inducing induce VBG cord-015569-vy49r1zd 651 21 pregnancy pregnancy NN cord-015569-vy49r1zd 651 22 block block NN cord-015569-vy49r1zd 651 23 . . . cord-015569-vy49r1zd 652 1 The the DT cord-015569-vy49r1zd 652 2 memory memory NN cord-015569-vy49r1zd 652 3 depends depend VBZ cord-015569-vy49r1zd 652 4 on on IN cord-015569-vy49r1zd 652 5 the the DT cord-015569-vy49r1zd 652 6 neural neural JJ cord-015569-vy49r1zd 652 7 changes change NNS cord-015569-vy49r1zd 652 8 in in IN cord-015569-vy49r1zd 652 9 the the DT cord-015569-vy49r1zd 652 10 accessory accessory JJ cord-015569-vy49r1zd 652 11 olfactory olfactory JJ cord-015569-vy49r1zd 652 12 bulb bulb NN cord-015569-vy49r1zd 652 13 ( ( -LRB- cord-015569-vy49r1zd 652 14 AOB AOB NNP cord-015569-vy49r1zd 652 15 ) ) -RRB- cord-015569-vy49r1zd 652 16 , , , cord-015569-vy49r1zd 652 17 the the DT cord-015569-vy49r1zd 652 18 first first JJ cord-015569-vy49r1zd 652 19 relay relay NN cord-015569-vy49r1zd 652 20 in in IN cord-015569-vy49r1zd 652 21 the the DT cord-015569-vy49r1zd 652 22 vomeronasal vomeronasal NN cord-015569-vy49r1zd 652 23 system system NN cord-015569-vy49r1zd 652 24 . . . cord-015569-vy49r1zd 653 1 Microcircuits microcircuit NNS cord-015569-vy49r1zd 653 2 in in IN cord-015569-vy49r1zd 653 3 the the DT cord-015569-vy49r1zd 653 4 AOB AOB NNP cord-015569-vy49r1zd 653 5 include include VBP cord-015569-vy49r1zd 653 6 the the DT cord-015569-vy49r1zd 653 7 prominent prominent JJ cord-015569-vy49r1zd 653 8 reciprocal reciprocal JJ cord-015569-vy49r1zd 653 9 dendrodendritic dendrodendritic JJ cord-015569-vy49r1zd 653 10 synapse synapse NN cord-015569-vy49r1zd 653 11 between between IN cord-015569-vy49r1zd 653 12 mitral mitral JJ cord-015569-vy49r1zd 653 13 cell cell NN cord-015569-vy49r1zd 653 14 projection projection NN cord-015569-vy49r1zd 653 15 neurons neuron NNS cord-015569-vy49r1zd 653 16 and and CC cord-015569-vy49r1zd 653 17 granule granule NN cord-015569-vy49r1zd 653 18 cell cell NN cord-015569-vy49r1zd 653 19 interneurons interneuron NNS cord-015569-vy49r1zd 653 20 . . . cord-015569-vy49r1zd 654 1 A a DT cord-015569-vy49r1zd 654 2 previous previous JJ cord-015569-vy49r1zd 654 3 study study NN cord-015569-vy49r1zd 654 4 has have VBZ cord-015569-vy49r1zd 654 5 shown show VBN cord-015569-vy49r1zd 654 6 that that IN cord-015569-vy49r1zd 654 7 in in IN cord-015569-vy49r1zd 654 8 vivo vivo NN cord-015569-vy49r1zd 654 9 infusion infusion NN cord-015569-vy49r1zd 654 10 of of IN cord-015569-vy49r1zd 654 11 a a DT cord-015569-vy49r1zd 654 12 protein protein NN cord-015569-vy49r1zd 654 13 synthesis synthesis NN cord-015569-vy49r1zd 654 14 inhibitor inhibitor NN cord-015569-vy49r1zd 654 15 , , , cord-015569-vy49r1zd 654 16 anisomycin anisomycin NNP cord-015569-vy49r1zd 654 17 , , , cord-015569-vy49r1zd 654 18 in in IN cord-015569-vy49r1zd 654 19 the the DT cord-015569-vy49r1zd 654 20 AOB AOB NNP cord-015569-vy49r1zd 654 21 is be VBZ cord-015569-vy49r1zd 654 22 able able JJ cord-015569-vy49r1zd 654 23 to to TO cord-015569-vy49r1zd 654 24 prevent prevent VB cord-015569-vy49r1zd 654 25 the the DT cord-015569-vy49r1zd 654 26 pheromonal pheromonal JJ cord-015569-vy49r1zd 654 27 memory memory NN cord-015569-vy49r1zd 654 28 formation formation NN cord-015569-vy49r1zd 654 29 . . . cord-015569-vy49r1zd 655 1 Other other JJ cord-015569-vy49r1zd 655 2 reports report NNS cord-015569-vy49r1zd 655 3 have have VBP cord-015569-vy49r1zd 655 4 indicated indicate VBN cord-015569-vy49r1zd 655 5 that that IN cord-015569-vy49r1zd 655 6 antidromical antidromical JJ cord-015569-vy49r1zd 655 7 stimulation stimulation NN cord-015569-vy49r1zd 655 8 of of IN cord-015569-vy49r1zd 655 9 mitral mitral JJ cord-015569-vy49r1zd 655 10 cell cell NN cord-015569-vy49r1zd 655 11 axons axon NNS cord-015569-vy49r1zd 655 12 induces induce VBZ cord-015569-vy49r1zd 655 13 long long JJ cord-015569-vy49r1zd 655 14 - - HYPH cord-015569-vy49r1zd 655 15 term term NN cord-015569-vy49r1zd 655 16 potentiation potentiation NN cord-015569-vy49r1zd 655 17 ( ( -LRB- cord-015569-vy49r1zd 655 18 LTP LTP NNP cord-015569-vy49r1zd 655 19 ) ) -RRB- cord-015569-vy49r1zd 655 20 at at IN cord-015569-vy49r1zd 655 21 the the DT cord-015569-vy49r1zd 655 22 mitral mitral JJ cord-015569-vy49r1zd 655 23 - - HYPH cord-015569-vy49r1zd 655 24 to to IN cord-015569-vy49r1zd 655 25 - - HYPH cord-015569-vy49r1zd 655 26 granule granule NN cord-015569-vy49r1zd 655 27 cell cell NN cord-015569-vy49r1zd 655 28 synapse synapse NN cord-015569-vy49r1zd 655 29 in in IN cord-015569-vy49r1zd 655 30 slice slice NN cord-015569-vy49r1zd 655 31 preparations preparation NNS cord-015569-vy49r1zd 655 32 of of IN cord-015569-vy49r1zd 655 33 the the DT cord-015569-vy49r1zd 655 34 AOB AOB NNP cord-015569-vy49r1zd 655 35 . . . cord-015569-vy49r1zd 656 1 Using use VBG cord-015569-vy49r1zd 656 2 AOB AOB NNP cord-015569-vy49r1zd 656 3 slices slice NNS cord-015569-vy49r1zd 656 4 , , , cord-015569-vy49r1zd 656 5 we -PRON- PRP cord-015569-vy49r1zd 656 6 measured measure VBD cord-015569-vy49r1zd 656 7 field field NN cord-015569-vy49r1zd 656 8 EPSPs epsp NNS cord-015569-vy49r1zd 656 9 derived derive VBN cord-015569-vy49r1zd 656 10 from from IN cord-015569-vy49r1zd 656 11 granule granule NN cord-015569-vy49r1zd 656 12 cells cell NNS cord-015569-vy49r1zd 656 13 to to TO cord-015569-vy49r1zd 656 14 examine examine VB cord-015569-vy49r1zd 656 15 the the DT cord-015569-vy49r1zd 656 16 effects effect NNS cord-015569-vy49r1zd 656 17 of of IN cord-015569-vy49r1zd 656 18 protein protein NN cord-015569-vy49r1zd 656 19 synthesis synthesis NN cord-015569-vy49r1zd 656 20 inhibition inhibition NN cord-015569-vy49r1zd 656 21 on on IN cord-015569-vy49r1zd 656 22 LTP LTP NNP cord-015569-vy49r1zd 656 23 at at IN cord-015569-vy49r1zd 656 24 the the DT cord-015569-vy49r1zd 656 25 mitral mitral JJ cord-015569-vy49r1zd 656 26 - - HYPH cord-015569-vy49r1zd 656 27 to to IN cord-015569-vy49r1zd 656 28 - - HYPH cord-015569-vy49r1zd 656 29 granule granule NN cord-015569-vy49r1zd 656 30 cell cell NN cord-015569-vy49r1zd 656 31 synapse synapse NN cord-015569-vy49r1zd 656 32 . . . cord-015569-vy49r1zd 657 1 High high JJ cord-015569-vy49r1zd 657 2 frequency frequency NN cord-015569-vy49r1zd 657 3 stimulation stimulation NN cord-015569-vy49r1zd 657 4 , , , cord-015569-vy49r1zd 657 5 consisting consist VBG cord-015569-vy49r1zd 657 6 of of IN cord-015569-vy49r1zd 657 7 a a DT cord-015569-vy49r1zd 657 8 100 100 CD cord-015569-vy49r1zd 657 9 Hz Hz NNP cord-015569-vy49r1zd 657 10 , , , cord-015569-vy49r1zd 657 11 100 100 CD cord-015569-vy49r1zd 657 12 pulse pulse NN cord-015569-vy49r1zd 657 13 train train NN cord-015569-vy49r1zd 657 14 applied apply VBD cord-015569-vy49r1zd 657 15 four four CD cord-015569-vy49r1zd 657 16 times time NNS cord-015569-vy49r1zd 657 17 at at IN cord-015569-vy49r1zd 657 18 3 3 CD cord-015569-vy49r1zd 657 19 min min NN cord-015569-vy49r1zd 657 20 intervals interval NNS cord-015569-vy49r1zd 657 21 , , , cord-015569-vy49r1zd 657 22 induced induce VBD cord-015569-vy49r1zd 657 23 LTP LTP NNP cord-015569-vy49r1zd 657 24 lasting last VBG cord-015569-vy49r1zd 657 25 for for IN cord-015569-vy49r1zd 657 26 180 180 CD cord-015569-vy49r1zd 657 27 min min NN cord-015569-vy49r1zd 657 28 . . . cord-015569-vy49r1zd 658 1 Under under IN cord-015569-vy49r1zd 658 2 bath bath NN cord-015569-vy49r1zd 658 3 application application NN cord-015569-vy49r1zd 658 4 of of IN cord-015569-vy49r1zd 658 5 anisomycin anisomycin NNP cord-015569-vy49r1zd 658 6 ( ( -LRB- cord-015569-vy49r1zd 658 7 20 20 CD cord-015569-vy49r1zd 658 8 lM lM NNP cord-015569-vy49r1zd 658 9 ) ) -RRB- cord-015569-vy49r1zd 658 10 , , , cord-015569-vy49r1zd 658 11 high high JJ cord-015569-vy49r1zd 658 12 frequency frequency NN cord-015569-vy49r1zd 658 13 stimulation stimulation NN cord-015569-vy49r1zd 658 14 induced induce VBD cord-015569-vy49r1zd 658 15 short short JJ cord-015569-vy49r1zd 658 16 - - HYPH cord-015569-vy49r1zd 658 17 term term NN cord-015569-vy49r1zd 658 18 potentiation potentiation NN cord-015569-vy49r1zd 658 19 and and CC cord-015569-vy49r1zd 658 20 early early JJ cord-015569-vy49r1zd 658 21 - - HYPH cord-015569-vy49r1zd 658 22 phase phase NN cord-015569-vy49r1zd 658 23 LTP LTP NNP cord-015569-vy49r1zd 658 24 , , , cord-015569-vy49r1zd 658 25 but but CC cord-015569-vy49r1zd 658 26 failed fail VBD cord-015569-vy49r1zd 658 27 to to TO cord-015569-vy49r1zd 658 28 induce induce VB cord-015569-vy49r1zd 658 29 late late JJ cord-015569-vy49r1zd 658 30 - - HYPH cord-015569-vy49r1zd 658 31 phase phase NN cord-015569-vy49r1zd 658 32 LTP LTP NNP cord-015569-vy49r1zd 658 33 . . . cord-015569-vy49r1zd 659 1 The the DT cord-015569-vy49r1zd 659 2 results result NNS cord-015569-vy49r1zd 659 3 suggest suggest VBP cord-015569-vy49r1zd 659 4 that that IN cord-015569-vy49r1zd 659 5 protein protein NN cord-015569-vy49r1zd 659 6 synthesis synthesis NN cord-015569-vy49r1zd 659 7 underlies underlie VBZ cord-015569-vy49r1zd 659 8 late late JJ cord-015569-vy49r1zd 659 9 - - HYPH cord-015569-vy49r1zd 659 10 phase phase NN cord-015569-vy49r1zd 659 11 LTP LTP NNP cord-015569-vy49r1zd 659 12 at at IN cord-015569-vy49r1zd 659 13 the the DT cord-015569-vy49r1zd 659 14 mitral mitral JJ cord-015569-vy49r1zd 659 15 - - HYPH cord-015569-vy49r1zd 659 16 to to IN cord-015569-vy49r1zd 659 17 - - HYPH cord-015569-vy49r1zd 659 18 granule granule NN cord-015569-vy49r1zd 659 19 cell cell NN cord-015569-vy49r1zd 659 20 synapse synapse NN cord-015569-vy49r1zd 659 21 in in IN cord-015569-vy49r1zd 659 22 the the DT cord-015569-vy49r1zd 659 23 AOB AOB NNP cord-015569-vy49r1zd 659 24 . . . cord-015569-vy49r1zd 660 1 The the DT cord-015569-vy49r1zd 660 2 goal goal NN cord-015569-vy49r1zd 660 3 of of IN cord-015569-vy49r1zd 660 4 our -PRON- PRP$ cord-015569-vy49r1zd 660 5 research research NN cord-015569-vy49r1zd 660 6 is be VBZ cord-015569-vy49r1zd 660 7 to to TO cord-015569-vy49r1zd 660 8 understand understand VB cord-015569-vy49r1zd 660 9 the the DT cord-015569-vy49r1zd 660 10 mechanism mechanism NN cord-015569-vy49r1zd 660 11 of of IN cord-015569-vy49r1zd 660 12 synaptic synaptic JJ cord-015569-vy49r1zd 660 13 transmission transmission NN cord-015569-vy49r1zd 660 14 in in IN cord-015569-vy49r1zd 660 15 the the DT cord-015569-vy49r1zd 660 16 AOB AOB NNP cord-015569-vy49r1zd 660 17 that that WDT cord-015569-vy49r1zd 660 18 has have VBZ cord-015569-vy49r1zd 660 19 been be VBN cord-015569-vy49r1zd 660 20 demonstrated demonstrate VBN cord-015569-vy49r1zd 660 21 to to TO cord-015569-vy49r1zd 660 22 be be VB cord-015569-vy49r1zd 660 23 critical critical JJ cord-015569-vy49r1zd 660 24 to to IN cord-015569-vy49r1zd 660 25 memory memory NN cord-015569-vy49r1zd 660 26 formation formation NN cord-015569-vy49r1zd 660 27 for for IN cord-015569-vy49r1zd 660 28 male male JJ cord-015569-vy49r1zd 660 29 mouse mouse NN cord-015569-vy49r1zd 660 30 pheromones pheromone NNS cord-015569-vy49r1zd 660 31 . . . cord-015569-vy49r1zd 661 1 By by IN cord-015569-vy49r1zd 661 2 measuring measure VBG cord-015569-vy49r1zd 661 3 the the DT cord-015569-vy49r1zd 661 4 reciprocal reciprocal JJ cord-015569-vy49r1zd 661 5 synaptic synaptic JJ cord-015569-vy49r1zd 661 6 currents current NNS cord-015569-vy49r1zd 661 7 from from IN cord-015569-vy49r1zd 661 8 mitral mitral JJ cord-015569-vy49r1zd 661 9 cells cell NNS cord-015569-vy49r1zd 661 10 in in IN cord-015569-vy49r1zd 661 11 the the DT cord-015569-vy49r1zd 661 12 AOB AOB NNP cord-015569-vy49r1zd 661 13 , , , cord-015569-vy49r1zd 661 14 we -PRON- PRP cord-015569-vy49r1zd 661 15 have have VBP cord-015569-vy49r1zd 661 16 demonstrated demonstrate VBN cord-015569-vy49r1zd 661 17 that that IN cord-015569-vy49r1zd 661 18 an an DT cord-015569-vy49r1zd 661 19 agonist agonist NN cord-015569-vy49r1zd 661 20 for for IN cord-015569-vy49r1zd 661 21 group group NN cord-015569-vy49r1zd 661 22 II II NNP cord-015569-vy49r1zd 661 23 metabotropic metabotropic NN cord-015569-vy49r1zd 661 24 glutamate glutamate NN cord-015569-vy49r1zd 661 25 receptors receptor NNS cord-015569-vy49r1zd 661 26 ( ( -LRB- cord-015569-vy49r1zd 661 27 mGluR2 mGluR2 NNP cord-015569-vy49r1zd 661 28 / / SYM cord-015569-vy49r1zd 661 29 mGluR3 mGluR3 NNP cord-015569-vy49r1zd 661 30 ) ) -RRB- cord-015569-vy49r1zd 661 31 , , , cord-015569-vy49r1zd 661 32 DCG DCG NNP cord-015569-vy49r1zd 661 33 - - HYPH cord-015569-vy49r1zd 661 34 IV IV NNP cord-015569-vy49r1zd 661 35 , , , cord-015569-vy49r1zd 661 36 suppressed suppress VBN cord-015569-vy49r1zd 661 37 dendrodendritic dendrodendritic JJ cord-015569-vy49r1zd 661 38 inhibition inhibition NN cord-015569-vy49r1zd 661 39 ( ( -LRB- cord-015569-vy49r1zd 661 40 DDI DDI NNP cord-015569-vy49r1zd 661 41 ) ) -RRB- cord-015569-vy49r1zd 661 42 in in IN cord-015569-vy49r1zd 661 43 a a DT cord-015569-vy49r1zd 661 44 reversible reversible JJ cord-015569-vy49r1zd 661 45 manner manner NN cord-015569-vy49r1zd 661 46 while while IN cord-015569-vy49r1zd 661 47 the the DT cord-015569-vy49r1zd 661 48 mGluR2 mGluR2 NNP cord-015569-vy49r1zd 661 49 / / SYM cord-015569-vy49r1zd 661 50 mGluR3 mGluR3 NNP cord-015569-vy49r1zd 661 51 antagonist antagonist NN cord-015569-vy49r1zd 661 52 LY341495 LY341495 NNP cord-015569-vy49r1zd 661 53 enhanced enhance VBD cord-015569-vy49r1zd 661 54 it -PRON- PRP cord-015569-vy49r1zd 661 55 . . . cord-015569-vy49r1zd 662 1 The the DT cord-015569-vy49r1zd 662 2 effects effect NNS cord-015569-vy49r1zd 662 3 of of IN cord-015569-vy49r1zd 662 4 these these DT cord-015569-vy49r1zd 662 5 drugs drug NNS cord-015569-vy49r1zd 662 6 were be VBD cord-015569-vy49r1zd 662 7 markedly markedly RB cord-015569-vy49r1zd 662 8 impaired impair VBN cord-015569-vy49r1zd 662 9 by by IN cord-015569-vy49r1zd 662 10 genetic genetic JJ cord-015569-vy49r1zd 662 11 ablation ablation NN cord-015569-vy49r1zd 662 12 of of IN cord-015569-vy49r1zd 662 13 mGluR2 mGluR2 NNP cord-015569-vy49r1zd 662 14 , , , cord-015569-vy49r1zd 662 15 indicating indicate VBG cord-015569-vy49r1zd 662 16 that that IN cord-015569-vy49r1zd 662 17 DCG DCG NNP cord-015569-vy49r1zd 662 18 - - HYPH cord-015569-vy49r1zd 662 19 IV IV NNP cord-015569-vy49r1zd 662 20 - - HYPH cord-015569-vy49r1zd 662 21 mediated mediate VBN cord-015569-vy49r1zd 662 22 suppression suppression NN cord-015569-vy49r1zd 662 23 of of IN cord-015569-vy49r1zd 662 24 DDI DDI NNP cord-015569-vy49r1zd 662 25 is be VBZ cord-015569-vy49r1zd 662 26 mediated mediate VBN cord-015569-vy49r1zd 662 27 by by IN cord-015569-vy49r1zd 662 28 mGluR2 mGluR2 NNP cord-015569-vy49r1zd 662 29 . . . cord-015569-vy49r1zd 663 1 In in IN cord-015569-vy49r1zd 663 2 these these DT cord-015569-vy49r1zd 663 3 studies study NNS cord-015569-vy49r1zd 663 4 , , , cord-015569-vy49r1zd 663 5 glutamate glutamate NN cord-015569-vy49r1zd 663 6 release release NN cord-015569-vy49r1zd 663 7 was be VBD cord-015569-vy49r1zd 663 8 triggered trigger VBN cord-015569-vy49r1zd 663 9 by by IN cord-015569-vy49r1zd 663 10 an an DT cord-015569-vy49r1zd 663 11 application application NN cord-015569-vy49r1zd 663 12 of of IN cord-015569-vy49r1zd 663 13 a a DT cord-015569-vy49r1zd 663 14 voltage voltage NN cord-015569-vy49r1zd 663 15 step step NN cord-015569-vy49r1zd 663 16 from from IN cord-015569-vy49r1zd 663 17 -70 -70 NN cord-015569-vy49r1zd 663 18 to to IN cord-015569-vy49r1zd 663 19 0 0 CD cord-015569-vy49r1zd 664 1 mV. mV. NNP cord-015569-vy49r1zd 665 1 In in IN cord-015569-vy49r1zd 665 2 the the DT cord-015569-vy49r1zd 665 3 present present JJ cord-015569-vy49r1zd 665 4 study study NN cord-015569-vy49r1zd 665 5 , , , cord-015569-vy49r1zd 665 6 to to TO cord-015569-vy49r1zd 665 7 see see VB cord-015569-vy49r1zd 665 8 whether whether IN cord-015569-vy49r1zd 665 9 mGluR2 mGluR2 NNP cord-015569-vy49r1zd 665 10 has have VBZ cord-015569-vy49r1zd 665 11 similar similar JJ cord-015569-vy49r1zd 665 12 effects effect NNS cord-015569-vy49r1zd 665 13 on on IN cord-015569-vy49r1zd 665 14 the the DT cord-015569-vy49r1zd 665 15 DDI DDI NNP cord-015569-vy49r1zd 665 16 elicited elicit VBN cord-015569-vy49r1zd 665 17 by by IN cord-015569-vy49r1zd 665 18 more more JJR cord-015569-vy49r1zd 665 19 physiological physiological JJ cord-015569-vy49r1zd 665 20 stimuli stimulus NNS cord-015569-vy49r1zd 665 21 , , , cord-015569-vy49r1zd 665 22 IPSPs ipsp NNS cord-015569-vy49r1zd 665 23 triggered trigger VBN cord-015569-vy49r1zd 665 24 by by IN cord-015569-vy49r1zd 665 25 spike spike NN cord-015569-vy49r1zd 665 26 trains train NNS cord-015569-vy49r1zd 665 27 in in IN cord-015569-vy49r1zd 665 28 mitral mitral JJ cord-015569-vy49r1zd 665 29 cells cell NNS cord-015569-vy49r1zd 665 30 in in IN cord-015569-vy49r1zd 665 31 slice slice NN cord-015569-vy49r1zd 665 32 preparations preparation NNS cord-015569-vy49r1zd 665 33 were be VBD cord-015569-vy49r1zd 665 34 recorded record VBN cord-015569-vy49r1zd 665 35 using use VBG cord-015569-vy49r1zd 665 36 the the DT cord-015569-vy49r1zd 665 37 patch patch NN cord-015569-vy49r1zd 665 38 - - HYPH cord-015569-vy49r1zd 665 39 clamp clamp NN cord-015569-vy49r1zd 665 40 technique technique NN cord-015569-vy49r1zd 665 41 in in IN cord-015569-vy49r1zd 665 42 whole whole JJ cord-015569-vy49r1zd 665 43 - - HYPH cord-015569-vy49r1zd 665 44 cell cell NN cord-015569-vy49r1zd 665 45 configuration configuration NN cord-015569-vy49r1zd 665 46 . . . cord-015569-vy49r1zd 666 1 AOB AOB NNP cord-015569-vy49r1zd 666 2 slices slice NNS cord-015569-vy49r1zd 666 3 were be VBD cord-015569-vy49r1zd 666 4 prepared prepare VBN cord-015569-vy49r1zd 666 5 from from IN cord-015569-vy49r1zd 666 6 23-to 23-to CD cord-015569-vy49r1zd 666 7 36-day 36-day CD cord-015569-vy49r1zd 666 8 - - HYPH cord-015569-vy49r1zd 666 9 old old JJ cord-015569-vy49r1zd 666 10 Balb Balb NNP cord-015569-vy49r1zd 666 11 / / SYM cord-015569-vy49r1zd 666 12 c c NN cord-015569-vy49r1zd 666 13 mice mouse NNS cord-015569-vy49r1zd 666 14 . . . cord-015569-vy49r1zd 667 1 LY341495 LY341495 NNP cord-015569-vy49r1zd 667 2 enhanced enhance VBD cord-015569-vy49r1zd 667 3 it -PRON- PRP cord-015569-vy49r1zd 667 4 . . . cord-015569-vy49r1zd 668 1 Together together RB cord-015569-vy49r1zd 668 2 with with IN cord-015569-vy49r1zd 668 3 previous previous JJ cord-015569-vy49r1zd 668 4 results result NNS cord-015569-vy49r1zd 668 5 , , , cord-015569-vy49r1zd 668 6 the the DT cord-015569-vy49r1zd 668 7 present present JJ cord-015569-vy49r1zd 668 8 result result NN cord-015569-vy49r1zd 668 9 suggests suggest VBZ cord-015569-vy49r1zd 668 10 that that IN cord-015569-vy49r1zd 668 11 mGluR2 mGluR2 NNP cord-015569-vy49r1zd 668 12 / / SYM cord-015569-vy49r1zd 668 13 mGluR3 mGluR3 NNP cord-015569-vy49r1zd 668 14 can can MD cord-015569-vy49r1zd 668 15 be be VB cord-015569-vy49r1zd 668 16 activated activate VBN cord-015569-vy49r1zd 668 17 by by IN cord-015569-vy49r1zd 668 18 endogenous endogenous JJ cord-015569-vy49r1zd 668 19 glutamate glutamate NN cord-015569-vy49r1zd 668 20 release release NN cord-015569-vy49r1zd 668 21 from from IN cord-015569-vy49r1zd 668 22 mitral mitral JJ cord-015569-vy49r1zd 668 23 cells cell NNS cord-015569-vy49r1zd 668 24 , , , cord-015569-vy49r1zd 668 25 which which WDT cord-015569-vy49r1zd 668 26 results result VBZ cord-015569-vy49r1zd 668 27 in in IN cord-015569-vy49r1zd 668 28 the the DT cord-015569-vy49r1zd 668 29 suppression suppression NN cord-015569-vy49r1zd 668 30 of of IN cord-015569-vy49r1zd 668 31 the the DT cord-015569-vy49r1zd 668 32 synaptic synaptic JJ cord-015569-vy49r1zd 668 33 transmission transmission NN cord-015569-vy49r1zd 668 34 from from IN cord-015569-vy49r1zd 668 35 mitral mitral JJ cord-015569-vy49r1zd 668 36 to to IN cord-015569-vy49r1zd 668 37 granule granule NN cord-015569-vy49r1zd 668 38 cells cell NNS cord-015569-vy49r1zd 668 39 in in IN cord-015569-vy49r1zd 668 40 the the DT cord-015569-vy49r1zd 668 41 AOB AOB NNP cord-015569-vy49r1zd 668 42 . . . cord-015569-vy49r1zd 669 1 Phenols phenol NNS cord-015569-vy49r1zd 669 2 are be VBP cord-015569-vy49r1zd 669 3 predominant predominant JJ cord-015569-vy49r1zd 669 4 in in IN cord-015569-vy49r1zd 669 5 the the DT cord-015569-vy49r1zd 669 6 total total JJ cord-015569-vy49r1zd 669 7 flavor flavor NN cord-015569-vy49r1zd 669 8 compounds compound NNS cord-015569-vy49r1zd 669 9 of of IN cord-015569-vy49r1zd 669 10 dried dry VBN cord-015569-vy49r1zd 669 11 bonito bonito NNP cord-015569-vy49r1zd 669 12 ( ( -LRB- cord-015569-vy49r1zd 669 13 Katsuobushi Katsuobushi NNP cord-015569-vy49r1zd 669 14 ) ) -RRB- cord-015569-vy49r1zd 669 15 . . . cord-015569-vy49r1zd 670 1 The the DT cord-015569-vy49r1zd 670 2 influence influence NN cord-015569-vy49r1zd 670 3 of of IN cord-015569-vy49r1zd 670 4 odors odor NNS cord-015569-vy49r1zd 670 5 of of IN cord-015569-vy49r1zd 670 6 1,3,5-trimethoxybenzene 1,3,5-trimethoxybenzene CD cord-015569-vy49r1zd 670 7 ( ( -LRB- cord-015569-vy49r1zd 670 8 TM TM NNP cord-015569-vy49r1zd 670 9 ; ; : cord-015569-vy49r1zd 670 10 M=168 M=168 NNP cord-015569-vy49r1zd 670 11 ) ) -RRB- cord-015569-vy49r1zd 670 12 , , , cord-015569-vy49r1zd 670 13 2,6-dimethoxyphenol 2,6-dimethoxyphenol CD cord-015569-vy49r1zd 670 14 ( ( -LRB- cord-015569-vy49r1zd 670 15 DT DT NNP cord-015569-vy49r1zd 670 16 ; ; : cord-015569-vy49r1zd 670 17 M=154 M=154 NNP cord-015569-vy49r1zd 670 18 ) ) -RRB- cord-015569-vy49r1zd 670 19 , , , cord-015569-vy49r1zd 670 20 and and CC cord-015569-vy49r1zd 670 21 guaiacol guaiacol NNP cord-015569-vy49r1zd 670 22 ( ( -LRB- cord-015569-vy49r1zd 670 23 GU GU NNP cord-015569-vy49r1zd 670 24 ; ; : cord-015569-vy49r1zd 670 25 M=124 m=124 ADD cord-015569-vy49r1zd 670 26 ) ) -RRB- cord-015569-vy49r1zd 670 27 , , , cord-015569-vy49r1zd 670 28 which which WDT cord-015569-vy49r1zd 670 29 were be VBD cord-015569-vy49r1zd 670 30 the the DT cord-015569-vy49r1zd 670 31 chemicals chemical NNS cord-015569-vy49r1zd 670 32 responsible responsible JJ cord-015569-vy49r1zd 670 33 for for IN cord-015569-vy49r1zd 670 34 the the DT cord-015569-vy49r1zd 670 35 Katsuobushi Katsuobushi NNP cord-015569-vy49r1zd 670 36 aroma aroma NN cord-015569-vy49r1zd 670 37 , , , cord-015569-vy49r1zd 670 38 on on IN cord-015569-vy49r1zd 670 39 the the DT cord-015569-vy49r1zd 670 40 production production NN cord-015569-vy49r1zd 670 41 of of IN cord-015569-vy49r1zd 670 42 b b NN cord-015569-vy49r1zd 670 43 - - HYPH cord-015569-vy49r1zd 670 44 endorphin endorphin NN cord-015569-vy49r1zd 670 45 ( ( -LRB- cord-015569-vy49r1zd 670 46 BE be VB cord-015569-vy49r1zd 670 47 ) ) -RRB- cord-015569-vy49r1zd 671 1 in in IN cord-015569-vy49r1zd 671 2 the the DT cord-015569-vy49r1zd 671 3 hypothalamus hypothalamus NN cord-015569-vy49r1zd 671 4 were be VBD cord-015569-vy49r1zd 671 5 examined examine VBN cord-015569-vy49r1zd 671 6 in in IN cord-015569-vy49r1zd 671 7 F344 f344 JJ cord-015569-vy49r1zd 671 8 male male JJ cord-015569-vy49r1zd 671 9 rats rat NNS cord-015569-vy49r1zd 671 10 . . . cord-015569-vy49r1zd 672 1 Rats rat NNS cord-015569-vy49r1zd 672 2 ( ( -LRB- cord-015569-vy49r1zd 672 3 5 5 CD cord-015569-vy49r1zd 672 4 weeks week NNS cord-015569-vy49r1zd 672 5 of of IN cord-015569-vy49r1zd 672 6 age age NN cord-015569-vy49r1zd 672 7 ) ) -RRB- cord-015569-vy49r1zd 672 8 were be VBD cord-015569-vy49r1zd 672 9 exposed expose VBN cord-015569-vy49r1zd 672 10 to to IN cord-015569-vy49r1zd 672 11 0.1 0.1 CD cord-015569-vy49r1zd 672 12 % % NN cord-015569-vy49r1zd 672 13 of of IN cord-015569-vy49r1zd 672 14 odors odor NNS cord-015569-vy49r1zd 672 15 dissolved dissolve VBN cord-015569-vy49r1zd 672 16 in in IN cord-015569-vy49r1zd 672 17 either either DT cord-015569-vy49r1zd 672 18 ethyl ethyl NN cord-015569-vy49r1zd 672 19 alcohol alcohol NN cord-015569-vy49r1zd 672 20 ( ( -LRB- cord-015569-vy49r1zd 672 21 EtOH EtOH NNP cord-015569-vy49r1zd 672 22 : : : cord-015569-vy49r1zd 672 23 M=46 M=46 NNP cord-015569-vy49r1zd 672 24 ) ) -RRB- cord-015569-vy49r1zd 672 25 or or CC cord-015569-vy49r1zd 672 26 triethyl triethyl NNP cord-015569-vy49r1zd 672 27 citrate citrate NNP cord-015569-vy49r1zd 673 1 ( ( -LRB- cord-015569-vy49r1zd 673 2 TEC TEC NNP cord-015569-vy49r1zd 673 3 : : : cord-015569-vy49r1zd 673 4 M=276 M=276 NNP cord-015569-vy49r1zd 673 5 ) ) -RRB- cord-015569-vy49r1zd 673 6 for for IN cord-015569-vy49r1zd 673 7 10h/ 10h/ CD cord-015569-vy49r1zd 673 8 day day NN cord-015569-vy49r1zd 673 9 for for IN cord-015569-vy49r1zd 673 10 one one CD cord-015569-vy49r1zd 673 11 or or CC cord-015569-vy49r1zd 673 12 two two CD cord-015569-vy49r1zd 673 13 weeks week NNS cord-015569-vy49r1zd 673 14 . . . cord-015569-vy49r1zd 674 1 BE be VB cord-015569-vy49r1zd 674 2 levels level NNS cord-015569-vy49r1zd 674 3 in in IN cord-015569-vy49r1zd 674 4 water water NN cord-015569-vy49r1zd 674 5 soluble soluble JJ cord-015569-vy49r1zd 674 6 extracts extract NNS cord-015569-vy49r1zd 674 7 of of IN cord-015569-vy49r1zd 674 8 hypothalamus hypothalamus NN cord-015569-vy49r1zd 674 9 were be VBD cord-015569-vy49r1zd 674 10 examined examine VBN cord-015569-vy49r1zd 674 11 by by IN cord-015569-vy49r1zd 674 12 ELISA ELISA NNP cord-015569-vy49r1zd 674 13 kits kit NNS cord-015569-vy49r1zd 674 14 . . . cord-015569-vy49r1zd 675 1 Among among IN cord-015569-vy49r1zd 675 2 three three CD cord-015569-vy49r1zd 675 3 phenols phenol NNS cord-015569-vy49r1zd 675 4 , , , cord-015569-vy49r1zd 675 5 TM TM NNP cord-015569-vy49r1zd 675 6 is be VBZ cord-015569-vy49r1zd 675 7 the the DT cord-015569-vy49r1zd 675 8 most most RBS cord-015569-vy49r1zd 675 9 potent potent JJ cord-015569-vy49r1zd 675 10 odor odor NN cord-015569-vy49r1zd 675 11 to to TO cord-015569-vy49r1zd 675 12 increase increase VB cord-015569-vy49r1zd 675 13 BE be NN cord-015569-vy49r1zd 675 14 levels level NNS cord-015569-vy49r1zd 675 15 in in IN cord-015569-vy49r1zd 675 16 rat rat NN cord-015569-vy49r1zd 675 17 hypothalamus hypothalamus NN cord-015569-vy49r1zd 675 18 , , , cord-015569-vy49r1zd 675 19 followed follow VBN cord-015569-vy49r1zd 675 20 by by IN cord-015569-vy49r1zd 675 21 DT DT NNP cord-015569-vy49r1zd 675 22 and and CC cord-015569-vy49r1zd 675 23 GU GU NNP cord-015569-vy49r1zd 675 24 : : : cord-015569-vy49r1zd 675 25 the the DT cord-015569-vy49r1zd 675 26 increasing increase VBG cord-015569-vy49r1zd 675 27 rate rate NN cord-015569-vy49r1zd 675 28 as as IN cord-015569-vy49r1zd 675 29 compared compare VBN cord-015569-vy49r1zd 675 30 with with IN cord-015569-vy49r1zd 675 31 the the DT cord-015569-vy49r1zd 675 32 control control NN cord-015569-vy49r1zd 675 33 was be VBD cord-015569-vy49r1zd 675 34 170 170 CD cord-015569-vy49r1zd 675 35 % % NN cord-015569-vy49r1zd 675 36 , , , cord-015569-vy49r1zd 675 37 160 160 CD cord-015569-vy49r1zd 675 38 % % NN cord-015569-vy49r1zd 675 39 and and CC cord-015569-vy49r1zd 675 40 140 140 CD cord-015569-vy49r1zd 675 41 % % NN cord-015569-vy49r1zd 675 42 , , , cord-015569-vy49r1zd 675 43 respectively respectively RB cord-015569-vy49r1zd 675 44 . . . cord-015569-vy49r1zd 676 1 These these DT cord-015569-vy49r1zd 676 2 phenols phenol NNS cord-015569-vy49r1zd 676 3 may may MD cord-015569-vy49r1zd 676 4 activate activate VB cord-015569-vy49r1zd 676 5 glomeruli glomeruli NN cord-015569-vy49r1zd 676 6 clusterd clusterd NN cord-015569-vy49r1zd 676 7 in in IN cord-015569-vy49r1zd 676 8 the the DT cord-015569-vy49r1zd 676 9 lateral lateral JJ cord-015569-vy49r1zd 676 10 domain domain NN cord-015569-vy49r1zd 676 11 of of IN cord-015569-vy49r1zd 676 12 the the DT cord-015569-vy49r1zd 676 13 dorsal dorsal JJ cord-015569-vy49r1zd 676 14 surface surface NN cord-015569-vy49r1zd 676 15 of of IN cord-015569-vy49r1zd 676 16 the the DT cord-015569-vy49r1zd 676 17 mammalian mammalian JJ cord-015569-vy49r1zd 676 18 olfactory olfactory JJ cord-015569-vy49r1zd 676 19 bulb bulb NN cord-015569-vy49r1zd 676 20 and and CC cord-015569-vy49r1zd 676 21 probably probably RB cord-015569-vy49r1zd 676 22 suppress suppress VB cord-015569-vy49r1zd 676 23 the the DT cord-015569-vy49r1zd 676 24 activities activity NNS cord-015569-vy49r1zd 676 25 of of IN cord-015569-vy49r1zd 676 26 sympathetic sympathetic JJ cord-015569-vy49r1zd 676 27 nervous nervous JJ cord-015569-vy49r1zd 676 28 system system NN cord-015569-vy49r1zd 676 29 . . . cord-015569-vy49r1zd 677 1 These these DT cord-015569-vy49r1zd 677 2 results result NNS cord-015569-vy49r1zd 677 3 suggest suggest VBP cord-015569-vy49r1zd 677 4 that that IN cord-015569-vy49r1zd 677 5 the the DT cord-015569-vy49r1zd 677 6 long long JJ cord-015569-vy49r1zd 677 7 - - HYPH cord-015569-vy49r1zd 677 8 term term NN cord-015569-vy49r1zd 677 9 exposure exposure NN cord-015569-vy49r1zd 677 10 to to IN cord-015569-vy49r1zd 677 11 bonito bonito NNP cord-015569-vy49r1zd 677 12 bouillon bouillon NN cord-015569-vy49r1zd 677 13 - - HYPH cord-015569-vy49r1zd 677 14 flavored flavor VBN cord-015569-vy49r1zd 677 15 diet diet NN cord-015569-vy49r1zd 677 16 enhanced enhance VBN cord-015569-vy49r1zd 677 17 ratÕs ratõs JJ cord-015569-vy49r1zd 677 18 preference preference NN cord-015569-vy49r1zd 677 19 for for IN cord-015569-vy49r1zd 677 20 bonito bonito NNP cord-015569-vy49r1zd 677 21 bouillon bouillon NNP cord-015569-vy49r1zd 677 22 . . . cord-015569-vy49r1zd 678 1 Neurogenesis neurogenesis NN cord-015569-vy49r1zd 678 2 occurs occur VBZ cord-015569-vy49r1zd 678 3 in in IN cord-015569-vy49r1zd 678 4 the the DT cord-015569-vy49r1zd 678 5 forebrain forebrain NNP cord-015569-vy49r1zd 678 6 subventricular subventricular NNP cord-015569-vy49r1zd 678 7 zone zone NNP cord-015569-vy49r1zd 678 8 ( ( -LRB- cord-015569-vy49r1zd 678 9 SVZ SVZ NNP cord-015569-vy49r1zd 678 10 ) ) -RRB- cord-015569-vy49r1zd 678 11 throughout throughout IN cord-015569-vy49r1zd 678 12 life life NN cord-015569-vy49r1zd 678 13 . . . cord-015569-vy49r1zd 679 1 These these DT cord-015569-vy49r1zd 679 2 neurons neuron NNS cord-015569-vy49r1zd 679 3 migrate migrate VBP cord-015569-vy49r1zd 679 4 to to IN cord-015569-vy49r1zd 679 5 the the DT cord-015569-vy49r1zd 679 6 main main JJ cord-015569-vy49r1zd 679 7 olfactory olfactory JJ cord-015569-vy49r1zd 679 8 bulb bulb NN cord-015569-vy49r1zd 679 9 ( ( -LRB- cord-015569-vy49r1zd 679 10 MOB MOB NNP cord-015569-vy49r1zd 679 11 ) ) -RRB- cord-015569-vy49r1zd 679 12 via via IN cord-015569-vy49r1zd 679 13 the the DT cord-015569-vy49r1zd 679 14 rostral rostral JJ cord-015569-vy49r1zd 679 15 migratory migratory JJ cord-015569-vy49r1zd 679 16 stream stream NN cord-015569-vy49r1zd 679 17 ( ( -LRB- cord-015569-vy49r1zd 679 18 RMS RMS NNP cord-015569-vy49r1zd 679 19 ) ) -RRB- cord-015569-vy49r1zd 679 20 , , , cord-015569-vy49r1zd 679 21 and and CC cord-015569-vy49r1zd 679 22 upon upon IN cord-015569-vy49r1zd 679 23 reaching reach VBG cord-015569-vy49r1zd 679 24 the the DT cord-015569-vy49r1zd 679 25 MOB mob NN cord-015569-vy49r1zd 679 26 they -PRON- PRP cord-015569-vy49r1zd 679 27 differentiate differentiate VBP cord-015569-vy49r1zd 679 28 into into IN cord-015569-vy49r1zd 679 29 granule granule NN cord-015569-vy49r1zd 679 30 cells cell NNS cord-015569-vy49r1zd 679 31 and and CC cord-015569-vy49r1zd 679 32 periglomerular periglomerular JJ cord-015569-vy49r1zd 679 33 cells cell NNS cord-015569-vy49r1zd 679 34 . . . cord-015569-vy49r1zd 680 1 The the DT cord-015569-vy49r1zd 680 2 information information NN cord-015569-vy49r1zd 680 3 broadcast broadcast VBN cord-015569-vy49r1zd 680 4 by by IN cord-015569-vy49r1zd 680 5 general general JJ cord-015569-vy49r1zd 680 6 odorants odorant NNS cord-015569-vy49r1zd 680 7 is be VBZ cord-015569-vy49r1zd 680 8 received receive VBN cord-015569-vy49r1zd 680 9 by by IN cord-015569-vy49r1zd 680 10 the the DT cord-015569-vy49r1zd 680 11 olfactory olfactory JJ cord-015569-vy49r1zd 680 12 sensory sensory JJ cord-015569-vy49r1zd 680 13 neurons neuron NNS cord-015569-vy49r1zd 680 14 and and CC cord-015569-vy49r1zd 680 15 transmitted transmit VBN cord-015569-vy49r1zd 680 16 to to IN cord-015569-vy49r1zd 680 17 the the DT cord-015569-vy49r1zd 680 18 MOB mob NN cord-015569-vy49r1zd 680 19 . . . cord-015569-vy49r1zd 681 1 Newly newly RB cord-015569-vy49r1zd 681 2 generated generate VBN cord-015569-vy49r1zd 681 3 neurons neuron NNS cord-015569-vy49r1zd 681 4 at at IN cord-015569-vy49r1zd 681 5 the the DT cord-015569-vy49r1zd 681 6 SVZ SVZ NNP cord-015569-vy49r1zd 681 7 play play VBP cord-015569-vy49r1zd 681 8 important important JJ cord-015569-vy49r1zd 681 9 roles role NNS cord-015569-vy49r1zd 681 10 in in IN cord-015569-vy49r1zd 681 11 odor odor NN cord-015569-vy49r1zd 681 12 discrimination discrimination NN cord-015569-vy49r1zd 681 13 and and CC cord-015569-vy49r1zd 681 14 odor odor NN cord-015569-vy49r1zd 681 15 memory memory NN cord-015569-vy49r1zd 681 16 . . . cord-015569-vy49r1zd 682 1 Recent recent JJ cord-015569-vy49r1zd 682 2 studies study NNS cord-015569-vy49r1zd 682 3 have have VBP cord-015569-vy49r1zd 682 4 shown show VBN cord-015569-vy49r1zd 682 5 that that DT cord-015569-vy49r1zd 682 6 reduction reduction NN cord-015569-vy49r1zd 682 7 of of IN cord-015569-vy49r1zd 682 8 mastication mastication NN cord-015569-vy49r1zd 682 9 impairs impair VBZ cord-015569-vy49r1zd 682 10 neurogenesis neurogenesis NN cord-015569-vy49r1zd 682 11 at at IN cord-015569-vy49r1zd 682 12 the the DT cord-015569-vy49r1zd 682 13 hippocampus hippocampus NN cord-015569-vy49r1zd 682 14 and and CC cord-015569-vy49r1zd 682 15 brain brain NN cord-015569-vy49r1zd 682 16 functions function NNS cord-015569-vy49r1zd 682 17 . . . cord-015569-vy49r1zd 683 1 In in IN cord-015569-vy49r1zd 683 2 the the DT cord-015569-vy49r1zd 683 3 present present JJ cord-015569-vy49r1zd 683 4 study study NN cord-015569-vy49r1zd 683 5 , , , cord-015569-vy49r1zd 683 6 bromodeoxyuridine bromodeoxyuridine NN cord-015569-vy49r1zd 683 7 - - HYPH cord-015569-vy49r1zd 683 8 immunoreactive immunoreactive NNP cord-015569-vy49r1zd 683 9 ( ( -LRB- cord-015569-vy49r1zd 683 10 BrdU BrdU NNP cord-015569-vy49r1zd 683 11 - - HYPH cord-015569-vy49r1zd 683 12 ir ir NNP cord-015569-vy49r1zd 683 13 ) ) -RRB- cord-015569-vy49r1zd 683 14 structures structure NNS cord-015569-vy49r1zd 683 15 in in IN cord-015569-vy49r1zd 683 16 the the DT cord-015569-vy49r1zd 683 17 sagittal sagittal JJ cord-015569-vy49r1zd 683 18 section section NN cord-015569-vy49r1zd 683 19 of of IN cord-015569-vy49r1zd 683 20 the the DT cord-015569-vy49r1zd 683 21 SVZ SVZ NNP cord-015569-vy49r1zd 683 22 , , , cord-015569-vy49r1zd 683 23 RMS RMS NNP cord-015569-vy49r1zd 683 24 , , , cord-015569-vy49r1zd 683 25 MOB mob NN cord-015569-vy49r1zd 683 26 and and CC cord-015569-vy49r1zd 683 27 accessory accessory JJ cord-015569-vy49r1zd 683 28 olfactory olfactory JJ cord-015569-vy49r1zd 683 29 bulb bulb NN cord-015569-vy49r1zd 683 30 ( ( -LRB- cord-015569-vy49r1zd 683 31 AOB AOB NNP cord-015569-vy49r1zd 683 32 ) ) -RRB- cord-015569-vy49r1zd 683 33 of of IN cord-015569-vy49r1zd 683 34 female female JJ cord-015569-vy49r1zd 683 35 adult adult NN cord-015569-vy49r1zd 683 36 mice mouse NNS cord-015569-vy49r1zd 683 37 fed feed VBD cord-015569-vy49r1zd 683 38 a a DT cord-015569-vy49r1zd 683 39 soft soft JJ cord-015569-vy49r1zd 683 40 diet diet NN cord-015569-vy49r1zd 683 41 were be VBD cord-015569-vy49r1zd 683 42 studied study VBN cord-015569-vy49r1zd 683 43 to to TO cord-015569-vy49r1zd 683 44 explore explore VB cord-015569-vy49r1zd 683 45 the the DT cord-015569-vy49r1zd 683 46 effects effect NNS cord-015569-vy49r1zd 683 47 of of IN cord-015569-vy49r1zd 683 48 reduction reduction NN cord-015569-vy49r1zd 683 49 of of IN cord-015569-vy49r1zd 683 50 mastication mastication NN cord-015569-vy49r1zd 683 51 on on IN cord-015569-vy49r1zd 683 52 newly newly RB cord-015569-vy49r1zd 683 53 generated generate VBN cord-015569-vy49r1zd 683 54 neurons neuron NNS cord-015569-vy49r1zd 683 55 at at IN cord-015569-vy49r1zd 683 56 the the DT cord-015569-vy49r1zd 683 57 SVZ SVZ NNP cord-015569-vy49r1zd 683 58 and and CC cord-015569-vy49r1zd 683 59 MOB MOB NNP cord-015569-vy49r1zd 683 60 . . . cord-015569-vy49r1zd 684 1 The the DT cord-015569-vy49r1zd 684 2 numbers number NNS cord-015569-vy49r1zd 684 3 of of IN cord-015569-vy49r1zd 684 4 BrdU BrdU NNP cord-015569-vy49r1zd 684 5 - - HYPH cord-015569-vy49r1zd 684 6 ir ir NNP cord-015569-vy49r1zd 684 7 cells cell NNS cord-015569-vy49r1zd 684 8 in in IN cord-015569-vy49r1zd 684 9 the the DT cord-015569-vy49r1zd 684 10 SVZ SVZ NNP cord-015569-vy49r1zd 684 11 of of IN cord-015569-vy49r1zd 684 12 adult adult NN cord-015569-vy49r1zd 684 13 mice mouse NNS cord-015569-vy49r1zd 684 14 fed feed VBD cord-015569-vy49r1zd 684 15 a a DT cord-015569-vy49r1zd 684 16 soft soft JJ cord-015569-vy49r1zd 684 17 diet diet NN cord-015569-vy49r1zd 684 18 for for IN cord-015569-vy49r1zd 684 19 1 1 CD cord-015569-vy49r1zd 684 20 , , , cord-015569-vy49r1zd 684 21 3 3 CD cord-015569-vy49r1zd 684 22 , , , cord-015569-vy49r1zd 684 23 or or CC cord-015569-vy49r1zd 684 24 6 6 CD cord-015569-vy49r1zd 684 25 months month NNS cord-015569-vy49r1zd 684 26 were be VBD cord-015569-vy49r1zd 684 27 lower low JJR cord-015569-vy49r1zd 684 28 than than IN cord-015569-vy49r1zd 684 29 those those DT cord-015569-vy49r1zd 684 30 of of IN cord-015569-vy49r1zd 684 31 mice mouse NNS cord-015569-vy49r1zd 684 32 fed feed VBD cord-015569-vy49r1zd 684 33 a a DT cord-015569-vy49r1zd 684 34 hard hard JJ cord-015569-vy49r1zd 684 35 diet diet NN cord-015569-vy49r1zd 684 36 . . . cord-015569-vy49r1zd 685 1 The the DT cord-015569-vy49r1zd 685 2 odor odor NN cord-015569-vy49r1zd 685 3 preferences preference NNS cord-015569-vy49r1zd 685 4 of of IN cord-015569-vy49r1zd 685 5 individual individual JJ cord-015569-vy49r1zd 685 6 female female JJ cord-015569-vy49r1zd 685 7 mice mouse NNS cord-015569-vy49r1zd 685 8 to to IN cord-015569-vy49r1zd 685 9 butyric butyric NN cord-015569-vy49r1zd 685 10 acid acid NN cord-015569-vy49r1zd 685 11 were be VBD cord-015569-vy49r1zd 685 12 tested test VBN cord-015569-vy49r1zd 685 13 in in IN cord-015569-vy49r1zd 685 14 a a DT cord-015569-vy49r1zd 685 15 Plexiglas Plexiglas NNP cord-015569-vy49r1zd 685 16 Y Y NNP cord-015569-vy49r1zd 685 17 - - HYPH cord-015569-vy49r1zd 685 18 maze maze NN cord-015569-vy49r1zd 685 19 preference preference NN cord-015569-vy49r1zd 685 20 apparatus apparatus NN cord-015569-vy49r1zd 685 21 . . . cord-015569-vy49r1zd 686 1 Feeding feed VBG cord-015569-vy49r1zd 686 2 the the DT cord-015569-vy49r1zd 686 3 soft soft JJ cord-015569-vy49r1zd 686 4 - - HYPH cord-015569-vy49r1zd 686 5 diet diet NN cord-015569-vy49r1zd 686 6 affected affect VBD cord-015569-vy49r1zd 686 7 the the DT cord-015569-vy49r1zd 686 8 adverse adverse JJ cord-015569-vy49r1zd 686 9 responses response NNS cord-015569-vy49r1zd 686 10 of of IN cord-015569-vy49r1zd 686 11 mice mouse NNS cord-015569-vy49r1zd 686 12 to to IN cord-015569-vy49r1zd 686 13 butyric butyric NN cord-015569-vy49r1zd 686 14 acid acid NN cord-015569-vy49r1zd 686 15 . . . cord-015569-vy49r1zd 687 1 The the DT cord-015569-vy49r1zd 687 2 results result NNS cord-015569-vy49r1zd 687 3 suggest suggest VBP cord-015569-vy49r1zd 687 4 that that IN cord-015569-vy49r1zd 687 5 feeding feed VBG cord-015569-vy49r1zd 687 6 with with IN cord-015569-vy49r1zd 687 7 a a DT cord-015569-vy49r1zd 687 8 soft soft JJ cord-015569-vy49r1zd 687 9 - - HYPH cord-015569-vy49r1zd 687 10 diet diet NN cord-015569-vy49r1zd 687 11 reduces reduce VBZ cord-015569-vy49r1zd 687 12 neurogenesis neurogenesis NN cord-015569-vy49r1zd 687 13 at at IN cord-015569-vy49r1zd 687 14 the the DT cord-015569-vy49r1zd 687 15 SVZ SVZ NNP cord-015569-vy49r1zd 687 16 , , , cord-015569-vy49r1zd 687 17 which which WDT cord-015569-vy49r1zd 687 18 in in IN cord-015569-vy49r1zd 687 19 turn turn NN cord-015569-vy49r1zd 687 20 reduces reduce VBZ cord-015569-vy49r1zd 687 21 olfactory olfactory JJ cord-015569-vy49r1zd 687 22 function function NN cord-015569-vy49r1zd 687 23 at at IN cord-015569-vy49r1zd 687 24 the the DT cord-015569-vy49r1zd 687 25 MOB mob NN cord-015569-vy49r1zd 687 26 . . . cord-015569-vy49r1zd 688 1 Epigenetic epigenetic JJ cord-015569-vy49r1zd 688 2 mechanisms mechanism NNS cord-015569-vy49r1zd 688 3 play play VBP cord-015569-vy49r1zd 688 4 an an DT cord-015569-vy49r1zd 688 5 important important JJ cord-015569-vy49r1zd 688 6 role role NN cord-015569-vy49r1zd 688 7 in in IN cord-015569-vy49r1zd 688 8 memory memory NN cord-015569-vy49r1zd 688 9 formation formation NN cord-015569-vy49r1zd 688 10 and and CC cord-015569-vy49r1zd 688 11 synaptic synaptic JJ cord-015569-vy49r1zd 688 12 plasticity plasticity NN cord-015569-vy49r1zd 688 13 . . . cord-015569-vy49r1zd 689 1 Specifically specifically RB cord-015569-vy49r1zd 689 2 , , , cord-015569-vy49r1zd 689 3 histone histone NN cord-015569-vy49r1zd 689 4 - - HYPH cord-015569-vy49r1zd 689 5 associated associate VBN cord-015569-vy49r1zd 689 6 heterochromatin heterochromatin NN cord-015569-vy49r1zd 689 7 undergoes undergo VBZ cord-015569-vy49r1zd 689 8 changes change NNS cord-015569-vy49r1zd 689 9 in in IN cord-015569-vy49r1zd 689 10 structure structure NN cord-015569-vy49r1zd 689 11 during during IN cord-015569-vy49r1zd 689 12 the the DT cord-015569-vy49r1zd 689 13 early early JJ cord-015569-vy49r1zd 689 14 stages stage NNS cord-015569-vy49r1zd 689 15 of of IN cord-015569-vy49r1zd 689 16 long long JJ cord-015569-vy49r1zd 689 17 - - HYPH cord-015569-vy49r1zd 689 18 term term NN cord-015569-vy49r1zd 689 19 memory memory NN cord-015569-vy49r1zd 689 20 formation formation NN cord-015569-vy49r1zd 689 21 . . . cord-015569-vy49r1zd 690 1 Before before IN cord-015569-vy49r1zd 690 2 eye eye NN cord-015569-vy49r1zd 690 3 opening open VBG cord-015569-vy49r1zd 690 4 young young JJ cord-015569-vy49r1zd 690 5 rats rat NNS cord-015569-vy49r1zd 690 6 depend depend VBP cord-015569-vy49r1zd 690 7 on on IN cord-015569-vy49r1zd 690 8 somatosensory somatosensory JJ cord-015569-vy49r1zd 690 9 and and CC cord-015569-vy49r1zd 690 10 olfactory olfactory JJ cord-015569-vy49r1zd 690 11 function function NN cord-015569-vy49r1zd 690 12 for for IN cord-015569-vy49r1zd 690 13 survival survival NN cord-015569-vy49r1zd 690 14 , , , cord-015569-vy49r1zd 690 15 as as IN cord-015569-vy49r1zd 690 16 they -PRON- PRP cord-015569-vy49r1zd 690 17 can can MD cord-015569-vy49r1zd 690 18 learn learn VB cord-015569-vy49r1zd 690 19 their -PRON- PRP$ cord-015569-vy49r1zd 690 20 damÕs damõs NN cord-015569-vy49r1zd 690 21 odor odor NN cord-015569-vy49r1zd 690 22 and and CC cord-015569-vy49r1zd 690 23 approach approach VB cord-015569-vy49r1zd 690 24 her -PRON- PRP cord-015569-vy49r1zd 690 25 without without IN cord-015569-vy49r1zd 690 26 visual visual JJ cord-015569-vy49r1zd 690 27 information information NN cord-015569-vy49r1zd 690 28 . . . cord-015569-vy49r1zd 691 1 In in IN cord-015569-vy49r1zd 691 2 order order NN cord-015569-vy49r1zd 691 3 to to TO cord-015569-vy49r1zd 691 4 establish establish VB cord-015569-vy49r1zd 691 5 olfactory olfactory JJ cord-015569-vy49r1zd 691 6 learning learning NN cord-015569-vy49r1zd 691 7 , , , cord-015569-vy49r1zd 691 8 the the DT cord-015569-vy49r1zd 691 9 pairing pairing NN cord-015569-vy49r1zd 691 10 of of IN cord-015569-vy49r1zd 691 11 odor odor NN cord-015569-vy49r1zd 691 12 and and CC cord-015569-vy49r1zd 691 13 somatosensory somatosensory JJ cord-015569-vy49r1zd 691 14 stimulation stimulation NN cord-015569-vy49r1zd 691 15 is be VBZ cord-015569-vy49r1zd 691 16 crucial crucial JJ cord-015569-vy49r1zd 691 17 . . . cord-015569-vy49r1zd 692 1 We -PRON- PRP cord-015569-vy49r1zd 692 2 have have VBP cord-015569-vy49r1zd 692 3 shown show VBN cord-015569-vy49r1zd 692 4 that that IN cord-015569-vy49r1zd 692 5 synaptic synaptic JJ cord-015569-vy49r1zd 692 6 plasticity plasticity NN cord-015569-vy49r1zd 692 7 in in IN cord-015569-vy49r1zd 692 8 the the DT cord-015569-vy49r1zd 692 9 OB OB NNP cord-015569-vy49r1zd 692 10 underlies underlie VBZ cord-015569-vy49r1zd 692 11 aversive aversive JJ cord-015569-vy49r1zd 692 12 olfactory olfactory JJ cord-015569-vy49r1zd 692 13 learning learning NN cord-015569-vy49r1zd 692 14 . . . cord-015569-vy49r1zd 693 1 Our -PRON- PRP$ cord-015569-vy49r1zd 693 2 behavioral behavioral JJ cord-015569-vy49r1zd 693 3 pharmacological pharmacological JJ cord-015569-vy49r1zd 693 4 experiments experiment NNS cord-015569-vy49r1zd 693 5 have have VBP cord-015569-vy49r1zd 693 6 shown show VBN cord-015569-vy49r1zd 693 7 that that IN cord-015569-vy49r1zd 693 8 long long JJ cord-015569-vy49r1zd 693 9 - - HYPH cord-015569-vy49r1zd 693 10 term term NN cord-015569-vy49r1zd 693 11 olfactory olfactory JJ cord-015569-vy49r1zd 693 12 memory memory NN cord-015569-vy49r1zd 693 13 requires require VBZ cord-015569-vy49r1zd 693 14 activation activation NN cord-015569-vy49r1zd 693 15 of of IN cord-015569-vy49r1zd 693 16 CREB CREB NNP cord-015569-vy49r1zd 693 17 . . . cord-015569-vy49r1zd 694 1 Western western JJ cord-015569-vy49r1zd 694 2 blot blot NN cord-015569-vy49r1zd 694 3 analyses analysis NNS cord-015569-vy49r1zd 694 4 have have VBP cord-015569-vy49r1zd 694 5 revealed reveal VBN cord-015569-vy49r1zd 694 6 that that DT cord-015569-vy49r1zd 694 7 expression expression NN cord-015569-vy49r1zd 694 8 of of IN cord-015569-vy49r1zd 694 9 P p NN cord-015569-vy49r1zd 694 10 - - HYPH cord-015569-vy49r1zd 694 11 MAPK MAPK NNP cord-015569-vy49r1zd 694 12 / / SYM cord-015569-vy49r1zd 694 13 ERK ERK NNP cord-015569-vy49r1zd 694 14 is be VBZ cord-015569-vy49r1zd 694 15 increased increase VBN cord-015569-vy49r1zd 694 16 for for IN cord-015569-vy49r1zd 694 17 1 1 CD cord-015569-vy49r1zd 694 18 hour hour NN cord-015569-vy49r1zd 694 19 after after IN cord-015569-vy49r1zd 694 20 odor odor NN cord-015569-vy49r1zd 694 21 - - HYPH cord-015569-vy49r1zd 694 22 shock shock NN cord-015569-vy49r1zd 694 23 training training NN cord-015569-vy49r1zd 694 24 , , , cord-015569-vy49r1zd 694 25 followed follow VBN cord-015569-vy49r1zd 694 26 by by IN cord-015569-vy49r1zd 694 27 increase increase NN cord-015569-vy49r1zd 694 28 of of IN cord-015569-vy49r1zd 694 29 P p NN cord-015569-vy49r1zd 694 30 - - HYPH cord-015569-vy49r1zd 694 31 CREB CREB NNP cord-015569-vy49r1zd 694 32 lasting last VBG cord-015569-vy49r1zd 694 33 for for IN cord-015569-vy49r1zd 694 34 6 6 CD cord-015569-vy49r1zd 694 35 hours hour NNS cord-015569-vy49r1zd 694 36 . . . cord-015569-vy49r1zd 695 1 Therefore therefore RB cord-015569-vy49r1zd 695 2 , , , cord-015569-vy49r1zd 695 3 we -PRON- PRP cord-015569-vy49r1zd 695 4 examined examine VBD cord-015569-vy49r1zd 695 5 whether whether IN cord-015569-vy49r1zd 695 6 intrabulbar intrabulbar NN cord-015569-vy49r1zd 695 7 infusion infusion NN cord-015569-vy49r1zd 695 8 of of IN cord-015569-vy49r1zd 695 9 trichostatin trichostatin NNP cord-015569-vy49r1zd 695 10 A A NNP cord-015569-vy49r1zd 695 11 ( ( -LRB- cord-015569-vy49r1zd 695 12 TSA TSA NNP cord-015569-vy49r1zd 695 13 ) ) -RRB- cord-015569-vy49r1zd 695 14 , , , cord-015569-vy49r1zd 695 15 a a DT cord-015569-vy49r1zd 695 16 histone histone NN cord-015569-vy49r1zd 695 17 deacetylase deacetylase NN cord-015569-vy49r1zd 695 18 ( ( -LRB- cord-015569-vy49r1zd 695 19 HDAC HDAC NNP cord-015569-vy49r1zd 695 20 ) ) -RRB- cord-015569-vy49r1zd 695 21 inhibitor inhibitor NN cord-015569-vy49r1zd 695 22 , , , cord-015569-vy49r1zd 695 23 facilitates facilitate VBZ cord-015569-vy49r1zd 695 24 olfactory olfactory JJ cord-015569-vy49r1zd 695 25 learning learn VBG cord-015569-vy49r1zd 695 26 in in IN cord-015569-vy49r1zd 695 27 young young JJ cord-015569-vy49r1zd 695 28 rats rat NNS cord-015569-vy49r1zd 695 29 . . . cord-015569-vy49r1zd 696 1 TSA TSA NNP cord-015569-vy49r1zd 696 2 infusion infusion NN cord-015569-vy49r1zd 696 3 during during IN cord-015569-vy49r1zd 696 4 odor odor NN cord-015569-vy49r1zd 696 5 - - HYPH cord-015569-vy49r1zd 696 6 shock shock NN cord-015569-vy49r1zd 696 7 training training NN cord-015569-vy49r1zd 696 8 enhanced enhance VBD cord-015569-vy49r1zd 696 9 a a DT cord-015569-vy49r1zd 696 10 conditioned condition VBN cord-015569-vy49r1zd 696 11 odor odor NN cord-015569-vy49r1zd 696 12 aversion aversion NN cord-015569-vy49r1zd 696 13 in in IN cord-015569-vy49r1zd 696 14 a a DT cord-015569-vy49r1zd 696 15 dose dose NN cord-015569-vy49r1zd 696 16 - - HYPH cord-015569-vy49r1zd 696 17 dependent dependent JJ cord-015569-vy49r1zd 696 18 manner manner NN cord-015569-vy49r1zd 696 19 . . . cord-015569-vy49r1zd 697 1 We -PRON- PRP cord-015569-vy49r1zd 697 2 further further RB cord-015569-vy49r1zd 697 3 tested test VBD cord-015569-vy49r1zd 697 4 whether whether IN cord-015569-vy49r1zd 697 5 odor odor NN cord-015569-vy49r1zd 697 6 - - HYPH cord-015569-vy49r1zd 697 7 shock shock NN cord-015569-vy49r1zd 697 8 training training NN cord-015569-vy49r1zd 697 9 leads lead VBZ cord-015569-vy49r1zd 697 10 to to IN cord-015569-vy49r1zd 697 11 histone histone NN cord-015569-vy49r1zd 697 12 acetylation acetylation NN cord-015569-vy49r1zd 697 13 in in IN cord-015569-vy49r1zd 697 14 the the DT cord-015569-vy49r1zd 697 15 OB OB NNP cord-015569-vy49r1zd 697 16 and and CC cord-015569-vy49r1zd 697 17 defined define VBD cord-015569-vy49r1zd 697 18 the the DT cord-015569-vy49r1zd 697 19 time time NN cord-015569-vy49r1zd 697 20 course course NN cord-015569-vy49r1zd 697 21 of of IN cord-015569-vy49r1zd 697 22 the the DT cord-015569-vy49r1zd 697 23 activation activation NN cord-015569-vy49r1zd 697 24 . . . cord-015569-vy49r1zd 698 1 The the DT cord-015569-vy49r1zd 698 2 acetylation acetylation NN cord-015569-vy49r1zd 698 3 of of IN cord-015569-vy49r1zd 698 4 histone histone NN cord-015569-vy49r1zd 698 5 H3 H3 NNP cord-015569-vy49r1zd 698 6 was be VBD cord-015569-vy49r1zd 698 7 significantly significantly RB cord-015569-vy49r1zd 698 8 increased increase VBN cord-015569-vy49r1zd 698 9 for for IN cord-015569-vy49r1zd 698 10 1 1 CD cord-015569-vy49r1zd 698 11 hour hour NN cord-015569-vy49r1zd 698 12 after after IN cord-015569-vy49r1zd 698 13 odor odor NN cord-015569-vy49r1zd 698 14 - - HYPH cord-015569-vy49r1zd 698 15 shock shock NN cord-015569-vy49r1zd 698 16 pairing pairing NN cord-015569-vy49r1zd 698 17 compared compare VBN cord-015569-vy49r1zd 698 18 with with IN cord-015569-vy49r1zd 698 19 odor odor NN cord-015569-vy49r1zd 698 20 only only RB cord-015569-vy49r1zd 698 21 or or CC cord-015569-vy49r1zd 698 22 no no DT cord-015569-vy49r1zd 698 23 stimulation stimulation NN cord-015569-vy49r1zd 698 24 . . . cord-015569-vy49r1zd 699 1 TSA TSA NNP cord-015569-vy49r1zd 699 2 infusion infusion NN cord-015569-vy49r1zd 699 3 significantly significantly RB cord-015569-vy49r1zd 699 4 increased increase VBD cord-015569-vy49r1zd 699 5 histone histone JJ cord-015569-vy49r1zd 699 6 acetylation acetylation NN cord-015569-vy49r1zd 699 7 levels level NNS cord-015569-vy49r1zd 699 8 as as RB cord-015569-vy49r1zd 699 9 well well RB cord-015569-vy49r1zd 699 10 . . . cord-015569-vy49r1zd 700 1 These these DT cord-015569-vy49r1zd 700 2 results result NNS cord-015569-vy49r1zd 700 3 show show VBP cord-015569-vy49r1zd 700 4 that that IN cord-015569-vy49r1zd 700 5 HDAC HDAC NNP cord-015569-vy49r1zd 700 6 inhibition inhibition NN cord-015569-vy49r1zd 700 7 is be VBZ cord-015569-vy49r1zd 700 8 associated associate VBN cord-015569-vy49r1zd 700 9 with with IN cord-015569-vy49r1zd 700 10 aversive aversive JJ cord-015569-vy49r1zd 700 11 olfactory olfactory JJ cord-015569-vy49r1zd 700 12 learning learning NN cord-015569-vy49r1zd 700 13 in in IN cord-015569-vy49r1zd 700 14 young young JJ cord-015569-vy49r1zd 700 15 rats rat NNS cord-015569-vy49r1zd 700 16 . . . cord-015569-vy49r1zd 701 1 The the DT cord-015569-vy49r1zd 701 2 endopiriform endopiriform JJ cord-015569-vy49r1zd 701 3 nucleus nucleus NN cord-015569-vy49r1zd 701 4 ( ( -LRB- cord-015569-vy49r1zd 701 5 EPN EPN NNP cord-015569-vy49r1zd 701 6 ) ) -RRB- cord-015569-vy49r1zd 701 7 is be VBZ cord-015569-vy49r1zd 701 8 a a DT cord-015569-vy49r1zd 701 9 large large JJ cord-015569-vy49r1zd 701 10 group group NN cord-015569-vy49r1zd 701 11 of of IN cord-015569-vy49r1zd 701 12 multipolar multipolar JJ cord-015569-vy49r1zd 701 13 cells cell NNS cord-015569-vy49r1zd 701 14 located locate VBN cord-015569-vy49r1zd 701 15 in in IN cord-015569-vy49r1zd 701 16 the the DT cord-015569-vy49r1zd 701 17 depth depth NN cord-015569-vy49r1zd 701 18 of of IN cord-015569-vy49r1zd 701 19 the the DT cord-015569-vy49r1zd 701 20 pirifprm pirifprm JJ cord-015569-vy49r1zd 701 21 cortex cortex NNP cord-015569-vy49r1zd 701 22 ( ( -LRB- cord-015569-vy49r1zd 701 23 PC PC NNP cord-015569-vy49r1zd 701 24 ) ) -RRB- cord-015569-vy49r1zd 701 25 . . . cord-015569-vy49r1zd 702 1 Although although IN cord-015569-vy49r1zd 702 2 many many JJ cord-015569-vy49r1zd 702 3 studies study NNS cord-015569-vy49r1zd 702 4 have have VBP cord-015569-vy49r1zd 702 5 suggested suggest VBN cord-015569-vy49r1zd 702 6 that that IN cord-015569-vy49r1zd 702 7 the the DT cord-015569-vy49r1zd 702 8 EPN EPN NNP cord-015569-vy49r1zd 702 9 plays play VBZ cord-015569-vy49r1zd 702 10 a a DT cord-015569-vy49r1zd 702 11 role role NN cord-015569-vy49r1zd 702 12 in in IN cord-015569-vy49r1zd 702 13 temporal temporal JJ cord-015569-vy49r1zd 702 14 lobe lobe NN cord-015569-vy49r1zd 702 15 epilepsy epilepsy NN cord-015569-vy49r1zd 702 16 , , , cord-015569-vy49r1zd 702 17 the the DT cord-015569-vy49r1zd 702 18 normal normal JJ cord-015569-vy49r1zd 702 19 function function NN cord-015569-vy49r1zd 702 20 of of IN cord-015569-vy49r1zd 702 21 the the DT cord-015569-vy49r1zd 702 22 EPN EPN NNP cord-015569-vy49r1zd 702 23 remains remain VBZ cord-015569-vy49r1zd 702 24 to to TO cord-015569-vy49r1zd 702 25 be be VB cord-015569-vy49r1zd 702 26 elucidated elucidate VBN cord-015569-vy49r1zd 702 27 . . . cord-015569-vy49r1zd 703 1 By by IN cord-015569-vy49r1zd 703 2 using use VBG cord-015569-vy49r1zd 703 3 optical optical JJ cord-015569-vy49r1zd 703 4 imaging imaging NN cord-015569-vy49r1zd 703 5 with with IN cord-015569-vy49r1zd 703 6 voltage voltage NN cord-015569-vy49r1zd 703 7 - - HYPH cord-015569-vy49r1zd 703 8 sensitive sensitive JJ cord-015569-vy49r1zd 703 9 dye dye NN cord-015569-vy49r1zd 703 10 in in IN cord-015569-vy49r1zd 703 11 slice slice NN cord-015569-vy49r1zd 703 12 preparations preparation NNS cord-015569-vy49r1zd 703 13 , , , cord-015569-vy49r1zd 703 14 we -PRON- PRP cord-015569-vy49r1zd 703 15 previously previously RB cord-015569-vy49r1zd 703 16 found find VBD cord-015569-vy49r1zd 703 17 that that IN cord-015569-vy49r1zd 703 18 paired pair VBN cord-015569-vy49r1zd 703 19 - - HYPH cord-015569-vy49r1zd 703 20 pulse pulse NN cord-015569-vy49r1zd 703 21 stimulation stimulation NN cord-015569-vy49r1zd 703 22 to to IN cord-015569-vy49r1zd 703 23 PC pc NN cord-015569-vy49r1zd 703 24 and/or and/or CC cord-015569-vy49r1zd 703 25 gustatory gustatory JJ cord-015569-vy49r1zd 703 26 cortex cortex NN cord-015569-vy49r1zd 703 27 ( ( -LRB- cord-015569-vy49r1zd 703 28 GC GC NNP cord-015569-vy49r1zd 703 29 ) ) -RRB- cord-015569-vy49r1zd 703 30 evoked evoke VBD cord-015569-vy49r1zd 703 31 the the DT cord-015569-vy49r1zd 703 32 excitation excitation NN cord-015569-vy49r1zd 703 33 propagation propagation NN cord-015569-vy49r1zd 703 34 to to IN cord-015569-vy49r1zd 703 35 the the DT cord-015569-vy49r1zd 703 36 EPN EPN NNP cord-015569-vy49r1zd 703 37 , , , cord-015569-vy49r1zd 703 38 agranular agranular NNP cord-015569-vy49r1zd 703 39 division division NN cord-015569-vy49r1zd 703 40 ( ( -LRB- cord-015569-vy49r1zd 703 41 AI AI NNP cord-015569-vy49r1zd 703 42 ) ) -RRB- cord-015569-vy49r1zd 703 43 of of IN cord-015569-vy49r1zd 703 44 the the DT cord-015569-vy49r1zd 703 45 insular insular JJ cord-015569-vy49r1zd 703 46 cortex cortex NN cord-015569-vy49r1zd 703 47 and and CC cord-015569-vy49r1zd 703 48 further further RB cord-015569-vy49r1zd 703 49 to to IN cord-015569-vy49r1zd 703 50 the the DT cord-015569-vy49r1zd 703 51 claustrum claustrum NNS cord-015569-vy49r1zd 703 52 ( ( -LRB- cord-015569-vy49r1zd 703 53 paired pair VBN cord-015569-vy49r1zd 703 54 - - HYPH cord-015569-vy49r1zd 703 55 pulse pulse NN cord-015569-vy49r1zd 703 56 facilitation facilitation NN cord-015569-vy49r1zd 703 57 ) ) -RRB- cord-015569-vy49r1zd 703 58 . . . cord-015569-vy49r1zd 704 1 In in IN cord-015569-vy49r1zd 704 2 the the DT cord-015569-vy49r1zd 704 3 present present JJ cord-015569-vy49r1zd 704 4 study study NN cord-015569-vy49r1zd 704 5 , , , cord-015569-vy49r1zd 704 6 we -PRON- PRP cord-015569-vy49r1zd 704 7 investigated investigate VBD cord-015569-vy49r1zd 704 8 the the DT cord-015569-vy49r1zd 704 9 electrophysiological electrophysiological JJ cord-015569-vy49r1zd 704 10 properties property NNS cord-015569-vy49r1zd 704 11 of of IN cord-015569-vy49r1zd 704 12 neurons neuron NNS cord-015569-vy49r1zd 704 13 in in IN cord-015569-vy49r1zd 704 14 the the DT cord-015569-vy49r1zd 704 15 EPN EPN NNP cord-015569-vy49r1zd 704 16 , , , cord-015569-vy49r1zd 704 17 claustrum claustrum NNP cord-015569-vy49r1zd 704 18 and and CC cord-015569-vy49r1zd 704 19 AI AI NNP cord-015569-vy49r1zd 704 20 in in IN cord-015569-vy49r1zd 704 21 anaesthetized anaesthetize VBN cord-015569-vy49r1zd 704 22 rats rat NNS cord-015569-vy49r1zd 704 23 . . . cord-015569-vy49r1zd 705 1 In in IN cord-015569-vy49r1zd 705 2 response response NN cord-015569-vy49r1zd 705 3 to to IN cord-015569-vy49r1zd 705 4 electrical electrical JJ cord-015569-vy49r1zd 705 5 stimulation stimulation NN cord-015569-vy49r1zd 705 6 of of IN cord-015569-vy49r1zd 705 7 the the DT cord-015569-vy49r1zd 705 8 olfactory olfactory JJ cord-015569-vy49r1zd 705 9 bulb bulb NN cord-015569-vy49r1zd 705 10 , , , cord-015569-vy49r1zd 705 11 the the DT cord-015569-vy49r1zd 705 12 evoked evoke VBN cord-015569-vy49r1zd 705 13 potentials potential NNS cord-015569-vy49r1zd 705 14 with with IN cord-015569-vy49r1zd 705 15 a a DT cord-015569-vy49r1zd 705 16 latency latency NN cord-015569-vy49r1zd 705 17 of of IN cord-015569-vy49r1zd 705 18 about about RB cord-015569-vy49r1zd 705 19 50 50 CD cord-015569-vy49r1zd 705 20 ms m NNS cord-015569-vy49r1zd 705 21 were be VBD cord-015569-vy49r1zd 705 22 elicited elicit VBN cord-015569-vy49r1zd 705 23 in in IN cord-015569-vy49r1zd 705 24 these these DT cord-015569-vy49r1zd 705 25 regions region NNS cord-015569-vy49r1zd 705 26 . . . cord-015569-vy49r1zd 706 1 Paired pair VBN cord-015569-vy49r1zd 706 2 - - HYPH cord-015569-vy49r1zd 706 3 pulse pulse NN cord-015569-vy49r1zd 706 4 facilitation facilitation NN cord-015569-vy49r1zd 706 5 of of IN cord-015569-vy49r1zd 706 6 the the DT cord-015569-vy49r1zd 706 7 evoked evoke VBN cord-015569-vy49r1zd 706 8 potential potential NN cord-015569-vy49r1zd 706 9 was be VBD cord-015569-vy49r1zd 706 10 also also RB cord-015569-vy49r1zd 706 11 observed observe VBN cord-015569-vy49r1zd 706 12 . . . cord-015569-vy49r1zd 707 1 Of of IN cord-015569-vy49r1zd 707 2 the the DT cord-015569-vy49r1zd 707 3 52 52 CD cord-015569-vy49r1zd 707 4 neurons neuron NNS cord-015569-vy49r1zd 707 5 in in IN cord-015569-vy49r1zd 707 6 these these DT cord-015569-vy49r1zd 707 7 regions region NNS cord-015569-vy49r1zd 707 8 tested test VBN cord-015569-vy49r1zd 707 9 with with IN cord-015569-vy49r1zd 707 10 odor odor NN cord-015569-vy49r1zd 707 11 and and CC cord-015569-vy49r1zd 707 12 gustatory gustatory JJ cord-015569-vy49r1zd 707 13 stimulation stimulation NN cord-015569-vy49r1zd 707 14 , , , cord-015569-vy49r1zd 707 15 8 8 CD cord-015569-vy49r1zd 707 16 ( ( -LRB- cord-015569-vy49r1zd 707 17 15 15 CD cord-015569-vy49r1zd 707 18 % % NN cord-015569-vy49r1zd 707 19 ) ) -RRB- cord-015569-vy49r1zd 707 20 showed show VBD cord-015569-vy49r1zd 707 21 excitatory excitatory JJ cord-015569-vy49r1zd 707 22 responses response NNS cord-015569-vy49r1zd 707 23 to to IN cord-015569-vy49r1zd 707 24 both both DT cord-015569-vy49r1zd 707 25 odor odor NN cord-015569-vy49r1zd 707 26 and and CC cord-015569-vy49r1zd 707 27 taste taste VBP cord-015569-vy49r1zd 707 28 stimulation stimulation NN cord-015569-vy49r1zd 707 29 , , , cord-015569-vy49r1zd 707 30 14 14 CD cord-015569-vy49r1zd 707 31 ( ( -LRB- cord-015569-vy49r1zd 707 32 27 27 CD cord-015569-vy49r1zd 707 33 % % NN cord-015569-vy49r1zd 707 34 ) ) -RRB- cord-015569-vy49r1zd 707 35 had have VBD cord-015569-vy49r1zd 707 36 excitatory excitatory JJ cord-015569-vy49r1zd 707 37 responses response NNS cord-015569-vy49r1zd 707 38 to to IN cord-015569-vy49r1zd 707 39 odor odor NN cord-015569-vy49r1zd 707 40 but but CC cord-015569-vy49r1zd 707 41 not not RB cord-015569-vy49r1zd 707 42 to to TO cord-015569-vy49r1zd 707 43 taste taste VB cord-015569-vy49r1zd 707 44 stimulation stimulation NN cord-015569-vy49r1zd 707 45 , , , cord-015569-vy49r1zd 707 46 2 2 CD cord-015569-vy49r1zd 707 47 ( ( -LRB- cord-015569-vy49r1zd 707 48 4 4 CD cord-015569-vy49r1zd 707 49 % % NN cord-015569-vy49r1zd 707 50 ) ) -RRB- cord-015569-vy49r1zd 707 51 had have VBD cord-015569-vy49r1zd 707 52 excitatory excitatory JJ cord-015569-vy49r1zd 707 53 responses response NNS cord-015569-vy49r1zd 707 54 to to TO cord-015569-vy49r1zd 707 55 taste taste VB cord-015569-vy49r1zd 708 1 but but CC cord-015569-vy49r1zd 708 2 not not RB cord-015569-vy49r1zd 708 3 to to TO cord-015569-vy49r1zd 708 4 odor odor VB cord-015569-vy49r1zd 708 5 stimulation stimulation NN cord-015569-vy49r1zd 708 6 , , , cord-015569-vy49r1zd 708 7 and and CC cord-015569-vy49r1zd 708 8 the the DT cord-015569-vy49r1zd 708 9 remaining remain VBG cord-015569-vy49r1zd 708 10 28 28 CD cord-015569-vy49r1zd 708 11 ( ( -LRB- cord-015569-vy49r1zd 708 12 54 54 CD cord-015569-vy49r1zd 708 13 % % NN cord-015569-vy49r1zd 708 14 ) ) -RRB- cord-015569-vy49r1zd 708 15 had have VBD cord-015569-vy49r1zd 708 16 no no DT cord-015569-vy49r1zd 708 17 response response NN cord-015569-vy49r1zd 708 18 . . . cord-015569-vy49r1zd 709 1 Further further RB cord-015569-vy49r1zd 709 2 , , , cord-015569-vy49r1zd 709 3 we -PRON- PRP cord-015569-vy49r1zd 709 4 previously previously RB cord-015569-vy49r1zd 709 5 found find VBD cord-015569-vy49r1zd 709 6 significant significant JJ cord-015569-vy49r1zd 709 7 increases increase NNS cord-015569-vy49r1zd 709 8 in in IN cord-015569-vy49r1zd 709 9 the the DT cord-015569-vy49r1zd 709 10 numbers number NNS cord-015569-vy49r1zd 709 11 of of IN cord-015569-vy49r1zd 709 12 c c LS cord-015569-vy49r1zd 709 13 - - : cord-015569-vy49r1zd 709 14 Fospositive fospositive JJ cord-015569-vy49r1zd 709 15 cells cell NNS cord-015569-vy49r1zd 709 16 in in IN cord-015569-vy49r1zd 709 17 the the DT cord-015569-vy49r1zd 709 18 PC pc NN cord-015569-vy49r1zd 709 19 , , , cord-015569-vy49r1zd 709 20 GC GC NNP cord-015569-vy49r1zd 709 21 , , , cord-015569-vy49r1zd 709 22 EPN EPN NNP cord-015569-vy49r1zd 709 23 , , , cord-015569-vy49r1zd 709 24 AI AI NNP cord-015569-vy49r1zd 709 25 and and CC cord-015569-vy49r1zd 709 26 claustrum claustrum NNP cord-015569-vy49r1zd 709 27 following follow VBG cord-015569-vy49r1zd 709 28 natural natural JJ cord-015569-vy49r1zd 709 29 stimuli stimulus NNS cord-015569-vy49r1zd 709 30 , , , cord-015569-vy49r1zd 709 31 such such JJ cord-015569-vy49r1zd 709 32 as as IN cord-015569-vy49r1zd 709 33 feeding feed VBG cord-015569-vy49r1zd 709 34 an an DT cord-015569-vy49r1zd 709 35 apple apple NN cord-015569-vy49r1zd 709 36 . . . cord-015569-vy49r1zd 710 1 These these DT cord-015569-vy49r1zd 710 2 results result NNS cord-015569-vy49r1zd 710 3 , , , cord-015569-vy49r1zd 710 4 together together RB cord-015569-vy49r1zd 710 5 with with IN cord-015569-vy49r1zd 710 6 previous previous JJ cord-015569-vy49r1zd 710 7 results result NNS cord-015569-vy49r1zd 710 8 , , , cord-015569-vy49r1zd 710 9 suggest suggest VBP cord-015569-vy49r1zd 710 10 that that IN cord-015569-vy49r1zd 710 11 the the DT cord-015569-vy49r1zd 710 12 EPN EPN NNP cord-015569-vy49r1zd 710 13 , , , cord-015569-vy49r1zd 710 14 claustrum claustrum NNP cord-015569-vy49r1zd 710 15 and and CC cord-015569-vy49r1zd 710 16 AI AI NNP cord-015569-vy49r1zd 710 17 are be VBP cord-015569-vy49r1zd 710 18 the the DT cord-015569-vy49r1zd 710 19 multimodal multimodal NN cord-015569-vy49r1zd 710 20 - - HYPH cord-015569-vy49r1zd 710 21 chemosensory chemosensory JJ cord-015569-vy49r1zd 710 22 regions region NNS cord-015569-vy49r1zd 710 23 , , , cord-015569-vy49r1zd 710 24 where where WRB cord-015569-vy49r1zd 710 25 olfactory olfactory JJ cord-015569-vy49r1zd 710 26 and and CC cord-015569-vy49r1zd 710 27 gustatory gustatory JJ cord-015569-vy49r1zd 710 28 information information NN cord-015569-vy49r1zd 710 29 is be VBZ cord-015569-vy49r1zd 710 30 centrally centrally RB cord-015569-vy49r1zd 710 31 integrated integrate VBN cord-015569-vy49r1zd 710 32 . . . cord-015569-vy49r1zd 711 1 Department Department NNP cord-015569-vy49r1zd 711 2 of of IN cord-015569-vy49r1zd 711 3 Science Science NNP cord-015569-vy49r1zd 711 4 Education Education NNP cord-015569-vy49r1zd 711 5 , , , cord-015569-vy49r1zd 711 6 Faculty Faculty NNP cord-015569-vy49r1zd 711 7 of of IN cord-015569-vy49r1zd 711 8 Education Education NNP cord-015569-vy49r1zd 711 9 , , , cord-015569-vy49r1zd 711 10 Chiba Chiba NNP cord-015569-vy49r1zd 711 11 University University NNP cord-015569-vy49r1zd 711 12 , , , cord-015569-vy49r1zd 711 13 Chiba Chiba NNP cord-015569-vy49r1zd 711 14 263 263 CD cord-015569-vy49r1zd 711 15 - - HYPH cord-015569-vy49r1zd 711 16 8522 8522 CD cord-015569-vy49r1zd 711 17 , , , cord-015569-vy49r1zd 711 18 Japan Japan NNP cord-015569-vy49r1zd 712 1 We -PRON- PRP cord-015569-vy49r1zd 712 2 found find VBD cord-015569-vy49r1zd 712 3 that that IN cord-015569-vy49r1zd 712 4 a a DT cord-015569-vy49r1zd 712 5 simple simple JJ cord-015569-vy49r1zd 712 6 and and CC cord-015569-vy49r1zd 712 7 typical typical JJ cord-015569-vy49r1zd 712 8 association association NN cord-015569-vy49r1zd 712 9 learning learning NN cord-015569-vy49r1zd 712 10 of of IN cord-015569-vy49r1zd 712 11 a a DT cord-015569-vy49r1zd 712 12 flower flower NN cord-015569-vy49r1zd 712 13 odor odor NN cord-015569-vy49r1zd 712 14 with with IN cord-015569-vy49r1zd 712 15 proboscis proboscis NN cord-015569-vy49r1zd 712 16 extension extension NN cord-015569-vy49r1zd 712 17 reflex reflex NN cord-015569-vy49r1zd 712 18 to to IN cord-015569-vy49r1zd 712 19 nectar nectar NN cord-015569-vy49r1zd 712 20 in in IN cord-015569-vy49r1zd 712 21 honeybees honeybee NNS cord-015569-vy49r1zd 712 22 was be VBD cord-015569-vy49r1zd 712 23 inhibited inhibit VBN cord-015569-vy49r1zd 712 24 by by IN cord-015569-vy49r1zd 712 25 exposure exposure NN cord-015569-vy49r1zd 712 26 to to IN cord-015569-vy49r1zd 712 27 extremely extremely RB cord-015569-vy49r1zd 712 28 low low JJ cord-015569-vy49r1zd 712 29 frequency frequency NN cord-015569-vy49r1zd 712 30 ( ( -LRB- cord-015569-vy49r1zd 712 31 ELF ELF NNP cord-015569-vy49r1zd 712 32 ) ) -RRB- cord-015569-vy49r1zd 712 33 alternating alternate VBG cord-015569-vy49r1zd 712 34 magnetic magnetic JJ cord-015569-vy49r1zd 712 35 fields field NNS cord-015569-vy49r1zd 712 36 . . . cord-015569-vy49r1zd 713 1 We -PRON- PRP cord-015569-vy49r1zd 713 2 postulated postulate VBD cord-015569-vy49r1zd 713 3 that that IN cord-015569-vy49r1zd 713 4 the the DT cord-015569-vy49r1zd 713 5 ELF ELF NNP cord-015569-vy49r1zd 713 6 magnetic magnetic JJ cord-015569-vy49r1zd 713 7 fields field NNS cord-015569-vy49r1zd 713 8 could could MD cord-015569-vy49r1zd 713 9 be be VB cord-015569-vy49r1zd 713 10 detected detect VBN cord-015569-vy49r1zd 713 11 by by IN cord-015569-vy49r1zd 713 12 magneto magneto NN cord-015569-vy49r1zd 713 13 - - HYPH cord-015569-vy49r1zd 713 14 receptors receptor NNS cord-015569-vy49r1zd 713 15 . . . cord-015569-vy49r1zd 714 1 Honeybees honeybee NNS cord-015569-vy49r1zd 714 2 have have VBP cord-015569-vy49r1zd 714 3 two two CD cord-015569-vy49r1zd 714 4 types type NNS cord-015569-vy49r1zd 714 5 of of IN cord-015569-vy49r1zd 714 6 putative putative JJ cord-015569-vy49r1zd 714 7 magneto magneto NN cord-015569-vy49r1zd 714 8 - - HYPH cord-015569-vy49r1zd 714 9 receptors receptor NNS cord-015569-vy49r1zd 714 10 which which WDT cord-015569-vy49r1zd 714 11 either either CC cord-015569-vy49r1zd 714 12 contain contain VBP cord-015569-vy49r1zd 714 13 magnetite magnetite JJ cord-015569-vy49r1zd 714 14 crystals crystal NNS cord-015569-vy49r1zd 714 15 , , , cord-015569-vy49r1zd 714 16 abdominal abdominal JJ cord-015569-vy49r1zd 714 17 dark dark JJ cord-015569-vy49r1zd 714 18 short short JJ cord-015569-vy49r1zd 714 19 hairs hair NNS cord-015569-vy49r1zd 714 20 or or CC cord-015569-vy49r1zd 714 21 abdominal abdominal JJ cord-015569-vy49r1zd 714 22 trophocystes trophocyste NNS cord-015569-vy49r1zd 714 23 . . . cord-015569-vy49r1zd 715 1 We -PRON- PRP cord-015569-vy49r1zd 715 2 previously previously RB cord-015569-vy49r1zd 715 3 reported report VBD cord-015569-vy49r1zd 715 4 that that IN cord-015569-vy49r1zd 715 5 a a DT cord-015569-vy49r1zd 715 6 cutting cutting NN cord-015569-vy49r1zd 715 7 of of IN cord-015569-vy49r1zd 715 8 the the DT cord-015569-vy49r1zd 715 9 abdomen abdomen JJ cord-015569-vy49r1zd 715 10 longitudinal longitudinal JJ cord-015569-vy49r1zd 715 11 connective connective JJ cord-015569-vy49r1zd 715 12 nerve nerve NN cord-015569-vy49r1zd 715 13 between between IN cord-015569-vy49r1zd 715 14 3rd 3rd JJ cord-015569-vy49r1zd 715 15 ganglion ganglion NN cord-015569-vy49r1zd 715 16 ( ( -LRB- cord-015569-vy49r1zd 715 17 first first JJ cord-015569-vy49r1zd 715 18 ganglion ganglion NN cord-015569-vy49r1zd 715 19 in in IN cord-015569-vy49r1zd 715 20 abdomen abdomen NN cord-015569-vy49r1zd 715 21 ) ) -RRB- cord-015569-vy49r1zd 715 22 and and CC cord-015569-vy49r1zd 715 23 4th 4th JJ cord-015569-vy49r1zd 715 24 ganglion ganglion NN cord-015569-vy49r1zd 715 25 had have VBD cord-015569-vy49r1zd 715 26 no no DT cord-015569-vy49r1zd 715 27 effect effect NN cord-015569-vy49r1zd 715 28 on on IN cord-015569-vy49r1zd 715 29 the the DT cord-015569-vy49r1zd 715 30 inhibitory inhibitory JJ cord-015569-vy49r1zd 715 31 action action NN cord-015569-vy49r1zd 715 32 of of IN cord-015569-vy49r1zd 715 33 alternating alternate VBG cord-015569-vy49r1zd 715 34 magnetic magnetic JJ cord-015569-vy49r1zd 715 35 fields field NNS cord-015569-vy49r1zd 715 36 . . . cord-015569-vy49r1zd 716 1 And and CC cord-015569-vy49r1zd 716 2 we -PRON- PRP cord-015569-vy49r1zd 716 3 concluded conclude VBD cord-015569-vy49r1zd 716 4 that that IN cord-015569-vy49r1zd 716 5 the the DT cord-015569-vy49r1zd 716 6 trophocystes trophocystes NNPS cord-015569-vy49r1zd 716 7 had have VBD cord-015569-vy49r1zd 716 8 no no DT cord-015569-vy49r1zd 716 9 role role NN cord-015569-vy49r1zd 716 10 in in IN cord-015569-vy49r1zd 716 11 magnetoreception magnetoreception NN cord-015569-vy49r1zd 716 12 . . . cord-015569-vy49r1zd 717 1 In in IN cord-015569-vy49r1zd 717 2 this this DT cord-015569-vy49r1zd 717 3 work work NN cord-015569-vy49r1zd 717 4 , , , cord-015569-vy49r1zd 717 5 we -PRON- PRP cord-015569-vy49r1zd 717 6 confirmed confirm VBD cord-015569-vy49r1zd 717 7 that that IN cord-015569-vy49r1zd 717 8 the the DT cord-015569-vy49r1zd 717 9 dark dark JJ cord-015569-vy49r1zd 717 10 hairs hair NNS cord-015569-vy49r1zd 717 11 had have VBD cord-015569-vy49r1zd 717 12 a a DT cord-015569-vy49r1zd 717 13 role role NN cord-015569-vy49r1zd 717 14 in in IN cord-015569-vy49r1zd 717 15 magnetoreception magnetoreception NN cord-015569-vy49r1zd 717 16 and and CC cord-015569-vy49r1zd 717 17 inhibitory inhibitory JJ cord-015569-vy49r1zd 717 18 action action NN cord-015569-vy49r1zd 717 19 of of IN cord-015569-vy49r1zd 717 20 olfactory olfactory JJ cord-015569-vy49r1zd 717 21 learning learning NN cord-015569-vy49r1zd 717 22 by by IN cord-015569-vy49r1zd 717 23 magnetic magnetic JJ cord-015569-vy49r1zd 717 24 fields field NNS cord-015569-vy49r1zd 717 25 . . . cord-015569-vy49r1zd 718 1 An an DT cord-015569-vy49r1zd 718 2 exposure exposure NN cord-015569-vy49r1zd 718 3 to to IN cord-015569-vy49r1zd 718 4 100Hz 100hz NN cord-015569-vy49r1zd 718 5 alternating alternate VBG cord-015569-vy49r1zd 718 6 magnetic magnetic JJ cord-015569-vy49r1zd 718 7 fields field NNS cord-015569-vy49r1zd 718 8 of of IN cord-015569-vy49r1zd 718 9 approximate approximate JJ cord-015569-vy49r1zd 718 10 450lT 450lt CD cord-015569-vy49r1zd 718 11 inhibited inhibit VBD cord-015569-vy49r1zd 718 12 the the DT cord-015569-vy49r1zd 718 13 performance performance NN cord-015569-vy49r1zd 718 14 of of IN cord-015569-vy49r1zd 718 15 conditioning conditioning NN cord-015569-vy49r1zd 718 16 learning learn VBG cord-015569-vy49r1zd 718 17 in in IN cord-015569-vy49r1zd 718 18 intact intact JJ cord-015569-vy49r1zd 718 19 bees bee NNS cord-015569-vy49r1zd 718 20 . . . cord-015569-vy49r1zd 719 1 When when WRB cord-015569-vy49r1zd 719 2 all all DT cord-015569-vy49r1zd 719 3 dark dark JJ cord-015569-vy49r1zd 719 4 hairs hair NNS cord-015569-vy49r1zd 719 5 were be VBD cord-015569-vy49r1zd 719 6 pull pull VBN cord-015569-vy49r1zd 719 7 out out RP cord-015569-vy49r1zd 719 8 , , , cord-015569-vy49r1zd 719 9 an an DT cord-015569-vy49r1zd 719 10 exposure exposure NN cord-015569-vy49r1zd 719 11 to to IN cord-015569-vy49r1zd 719 12 alternating alternate VBG cord-015569-vy49r1zd 719 13 magnetic magnetic JJ cord-015569-vy49r1zd 719 14 fields field NNS cord-015569-vy49r1zd 719 15 had have VBD cord-015569-vy49r1zd 719 16 no no DT cord-015569-vy49r1zd 719 17 inhibitory inhibitory JJ cord-015569-vy49r1zd 719 18 effects effect NNS cord-015569-vy49r1zd 719 19 on on IN cord-015569-vy49r1zd 719 20 the the DT cord-015569-vy49r1zd 719 21 conditioning conditioning NN cord-015569-vy49r1zd 719 22 . . . cord-015569-vy49r1zd 720 1 So so RB cord-015569-vy49r1zd 720 2 , , , cord-015569-vy49r1zd 720 3 it -PRON- PRP cord-015569-vy49r1zd 720 4 was be VBD cord-015569-vy49r1zd 720 5 shown show VBN cord-015569-vy49r1zd 720 6 that that IN cord-015569-vy49r1zd 720 7 the the DT cord-015569-vy49r1zd 720 8 dark dark JJ cord-015569-vy49r1zd 720 9 hairs hair NNS cord-015569-vy49r1zd 720 10 had have VBD cord-015569-vy49r1zd 720 11 a a DT cord-015569-vy49r1zd 720 12 role role NN cord-015569-vy49r1zd 720 13 in in IN cord-015569-vy49r1zd 720 14 magnetoreception magnetoreception NN cord-015569-vy49r1zd 720 15 which which WDT cord-015569-vy49r1zd 720 16 impaired impair VBD cord-015569-vy49r1zd 720 17 olfactory olfactory JJ cord-015569-vy49r1zd 720 18 learning learning NN cord-015569-vy49r1zd 720 19 . . . cord-015569-vy49r1zd 721 1 # # $ cord-015569-vy49r1zd 721 2 66 66 CD cord-015569-vy49r1zd 721 3 Prediction prediction NN cord-015569-vy49r1zd 721 4 of of IN cord-015569-vy49r1zd 721 5 glomerular glomerular JJ cord-015569-vy49r1zd 721 6 activity activity NN cord-015569-vy49r1zd 721 7 patterns pattern NNS cord-015569-vy49r1zd 721 8 using use VBG cord-015569-vy49r1zd 721 9 the the DT cord-015569-vy49r1zd 721 10 graph graph NN cord-015569-vy49r1zd 721 11 structure structure NN cord-015569-vy49r1zd 721 12 of of IN cord-015569-vy49r1zd 721 13 odorant odorant NN cord-015569-vy49r1zd 721 14 molecules molecule NNS cord-015569-vy49r1zd 721 15 Zu Zu NNP cord-015569-vy49r1zd 721 16 Soh Soh NNP cord-015569-vy49r1zd 721 17 1 1 CD cord-015569-vy49r1zd 721 18 , , , cord-015569-vy49r1zd 721 19 Toshio Toshio NNP cord-015569-vy49r1zd 721 20 Tsuji Tsuji NNP cord-015569-vy49r1zd 721 21 2 2 CD cord-015569-vy49r1zd 721 22 , , , cord-015569-vy49r1zd 721 23 Yuichi Yuichi NNP cord-015569-vy49r1zd 721 24 Kurita Kurita NNP cord-015569-vy49r1zd 721 25 2 2 CD cord-015569-vy49r1zd 721 26 , , , cord-015569-vy49r1zd 721 27 Noboru Noboru NNP cord-015569-vy49r1zd 721 28 Takiguchi Takiguchi NNP cord-015569-vy49r1zd 721 29 3 3 CD cord-015569-vy49r1zd 721 30 and and CC cord-015569-vy49r1zd 721 31 Hisao Hisao NNP cord-015569-vy49r1zd 721 32 Ohtake Ohtake NNP cord-015569-vy49r1zd 721 33 1 1 CD cord-015569-vy49r1zd 721 34 1 1 CD cord-015569-vy49r1zd 721 35 Grad Grad NNP cord-015569-vy49r1zd 721 36 . . . cord-015569-vy49r1zd 722 1 School School NNP cord-015569-vy49r1zd 722 2 of of IN cord-015569-vy49r1zd 722 3 Engineering Engineering NNP cord-015569-vy49r1zd 722 4 , , , cord-015569-vy49r1zd 722 5 Osaka Osaka NNP cord-015569-vy49r1zd 722 6 Univ Univ NNP cord-015569-vy49r1zd 722 7 . . NNP cord-015569-vy49r1zd 722 8 , , , cord-015569-vy49r1zd 723 1 Suita Suita NNP cord-015569-vy49r1zd 723 2 565 565 CD cord-015569-vy49r1zd 723 3 - - HYPH cord-015569-vy49r1zd 723 4 0871 0871 CD cord-015569-vy49r1zd 723 5 , , , cord-015569-vy49r1zd 723 6 2 2 CD cord-015569-vy49r1zd 723 7 Grad grad NN cord-015569-vy49r1zd 723 8 . . . cord-015569-vy49r1zd 724 1 School School NNP cord-015569-vy49r1zd 724 2 of of IN cord-015569-vy49r1zd 724 3 Engineering Engineering NNP cord-015569-vy49r1zd 724 4 , , , cord-015569-vy49r1zd 724 5 Hiroshima Hiroshima NNP cord-015569-vy49r1zd 724 6 Univ Univ NNP cord-015569-vy49r1zd 724 7 . . . cord-015569-vy49r1zd 725 1 , , , cord-015569-vy49r1zd 725 2 Higashihiroshima Higashihiroshima NNP cord-015569-vy49r1zd 725 3 739 739 CD cord-015569-vy49r1zd 725 4 - - HYPH cord-015569-vy49r1zd 725 5 8527 8527 CD cord-015569-vy49r1zd 725 6 , , , cord-015569-vy49r1zd 725 7 3 3 CD cord-015569-vy49r1zd 725 8 Grad grad NN cord-015569-vy49r1zd 725 9 . . . cord-015569-vy49r1zd 726 1 School school NN cord-015569-vy49r1zd 726 2 of of IN cord-015569-vy49r1zd 726 3 Natural Natural NNP cord-015569-vy49r1zd 726 4 Science Science NNP cord-015569-vy49r1zd 726 5 and and CC cord-015569-vy49r1zd 726 6 Technology Technology NNP cord-015569-vy49r1zd 726 7 , , , cord-015569-vy49r1zd 726 8 Kanazawa Kanazawa NNP cord-015569-vy49r1zd 726 9 Univ Univ NNP cord-015569-vy49r1zd 726 10 . . NNP cord-015569-vy49r1zd 726 11 , , , cord-015569-vy49r1zd 727 1 Quantitative quantitative JJ cord-015569-vy49r1zd 727 2 evaluation evaluation NN cord-015569-vy49r1zd 727 3 of of IN cord-015569-vy49r1zd 727 4 odor odor NN cord-015569-vy49r1zd 727 5 qualities quality NNS cord-015569-vy49r1zd 727 6 is be VBZ cord-015569-vy49r1zd 727 7 an an DT cord-015569-vy49r1zd 727 8 important important JJ cord-015569-vy49r1zd 727 9 process process NN cord-015569-vy49r1zd 727 10 especially especially RB cord-015569-vy49r1zd 727 11 in in IN cord-015569-vy49r1zd 727 12 the the DT cord-015569-vy49r1zd 727 13 fragrance fragrance NN cord-015569-vy49r1zd 727 14 , , , cord-015569-vy49r1zd 727 15 food food NN cord-015569-vy49r1zd 727 16 and and CC cord-015569-vy49r1zd 727 17 beverage beverage NN cord-015569-vy49r1zd 727 18 industries industry NNS cord-015569-vy49r1zd 727 19 . . . cord-015569-vy49r1zd 728 1 However however RB cord-015569-vy49r1zd 728 2 , , , cord-015569-vy49r1zd 728 3 most most JJS cord-015569-vy49r1zd 728 4 of of IN cord-015569-vy49r1zd 728 5 the the DT cord-015569-vy49r1zd 728 6 conventional conventional JJ cord-015569-vy49r1zd 728 7 odor odor NN cord-015569-vy49r1zd 728 8 sensing sense VBG cord-015569-vy49r1zd 728 9 systems system NNS cord-015569-vy49r1zd 728 10 are be VBP cord-015569-vy49r1zd 728 11 unable unable JJ cord-015569-vy49r1zd 728 12 to to TO cord-015569-vy49r1zd 728 13 assess assess VB cord-015569-vy49r1zd 728 14 odor odor NN cord-015569-vy49r1zd 728 15 qualities quality NNS cord-015569-vy49r1zd 728 16 perceived perceive VBN cord-015569-vy49r1zd 728 17 by by IN cord-015569-vy49r1zd 728 18 humans human NNS cord-015569-vy49r1zd 728 19 . . . cord-015569-vy49r1zd 729 1 This this DT cord-015569-vy49r1zd 729 2 study study NN cord-015569-vy49r1zd 729 3 therefore therefore RB cord-015569-vy49r1zd 729 4 aims aim VBZ cord-015569-vy49r1zd 729 5 to to TO cord-015569-vy49r1zd 729 6 develop develop VB cord-015569-vy49r1zd 729 7 an an DT cord-015569-vy49r1zd 729 8 artificial artificial JJ cord-015569-vy49r1zd 729 9 sensory sensory JJ cord-015569-vy49r1zd 729 10 evaluation evaluation NN cord-015569-vy49r1zd 729 11 system system NN cord-015569-vy49r1zd 729 12 that that WDT cord-015569-vy49r1zd 729 13 can can MD cord-015569-vy49r1zd 729 14 be be VB cord-015569-vy49r1zd 729 15 used use VBN cord-015569-vy49r1zd 729 16 to to TO cord-015569-vy49r1zd 729 17 evaluate evaluate VB cord-015569-vy49r1zd 729 18 odors odor NNS cord-015569-vy49r1zd 729 19 and and CC cord-015569-vy49r1zd 729 20 support support VB cord-015569-vy49r1zd 729 21 sensory sensory JJ cord-015569-vy49r1zd 729 22 testing testing NN cord-015569-vy49r1zd 729 23 . . . cord-015569-vy49r1zd 730 1 As as IN cord-015569-vy49r1zd 730 2 the the DT cord-015569-vy49r1zd 730 3 first first JJ cord-015569-vy49r1zd 730 4 step step NN cord-015569-vy49r1zd 730 5 in in IN cord-015569-vy49r1zd 730 6 the the DT cord-015569-vy49r1zd 730 7 development development NN cord-015569-vy49r1zd 730 8 of of IN cord-015569-vy49r1zd 730 9 such such PDT cord-015569-vy49r1zd 730 10 a a DT cord-015569-vy49r1zd 730 11 system system NN cord-015569-vy49r1zd 730 12 , , , cord-015569-vy49r1zd 730 13 we -PRON- PRP cord-015569-vy49r1zd 730 14 proposed propose VBD cord-015569-vy49r1zd 730 15 a a DT cord-015569-vy49r1zd 730 16 neural neural JJ cord-015569-vy49r1zd 730 17 network network NN cord-015569-vy49r1zd 730 18 model model NN cord-015569-vy49r1zd 730 19 for for IN cord-015569-vy49r1zd 730 20 prediction prediction NN cord-015569-vy49r1zd 730 21 of of IN cord-015569-vy49r1zd 730 22 olfactory olfactory JJ cord-015569-vy49r1zd 730 23 glomerular glomerular JJ cord-015569-vy49r1zd 730 24 activity activity NN cord-015569-vy49r1zd 730 25 based base VBN cord-015569-vy49r1zd 730 26 on on IN cord-015569-vy49r1zd 730 27 the the DT cord-015569-vy49r1zd 730 28 results result NNS cord-015569-vy49r1zd 730 29 of of IN cord-015569-vy49r1zd 730 30 previous previous JJ cord-015569-vy49r1zd 730 31 studies study NNS cord-015569-vy49r1zd 730 32 , , , cord-015569-vy49r1zd 730 33 which which WDT cord-015569-vy49r1zd 730 34 reported report VBD cord-015569-vy49r1zd 730 35 that that IN cord-015569-vy49r1zd 730 36 odors odor NNS cord-015569-vy49r1zd 730 37 evoking evoke VBG cord-015569-vy49r1zd 730 38 similar similar JJ cord-015569-vy49r1zd 730 39 glomerular glomerular JJ cord-015569-vy49r1zd 730 40 activity activity NN cord-015569-vy49r1zd 730 41 patterns pattern NNS cord-015569-vy49r1zd 730 42 have have VBP cord-015569-vy49r1zd 730 43 similar similar JJ cord-015569-vy49r1zd 730 44 odorant odorant NN cord-015569-vy49r1zd 730 45 qualities quality NNS cord-015569-vy49r1zd 730 46 . . . cord-015569-vy49r1zd 731 1 The the DT cord-015569-vy49r1zd 731 2 proposed propose VBN cord-015569-vy49r1zd 731 3 model model NN cord-015569-vy49r1zd 731 4 consists consist VBZ cord-015569-vy49r1zd 731 5 of of IN cord-015569-vy49r1zd 731 6 marginalized marginalize VBN cord-015569-vy49r1zd 731 7 graph graph NN cord-015569-vy49r1zd 731 8 kernels kernel NNS cord-015569-vy49r1zd 731 9 and and CC cord-015569-vy49r1zd 731 10 a a DT cord-015569-vy49r1zd 731 11 multilayer multilayer JJ cord-015569-vy49r1zd 731 12 neural neural JJ cord-015569-vy49r1zd 731 13 network network NN cord-015569-vy49r1zd 731 14 . . . cord-015569-vy49r1zd 732 1 The the DT cord-015569-vy49r1zd 732 2 former former JJ cord-015569-vy49r1zd 732 3 is be VBZ cord-015569-vy49r1zd 732 4 used use VBN cord-015569-vy49r1zd 732 5 to to TO cord-015569-vy49r1zd 732 6 evaluate evaluate VB cord-015569-vy49r1zd 732 7 distances distance NNS cord-015569-vy49r1zd 732 8 between between IN cord-015569-vy49r1zd 732 9 odorant odorant NN cord-015569-vy49r1zd 732 10 structures structure NNS cord-015569-vy49r1zd 732 11 , , , cord-015569-vy49r1zd 732 12 and and CC cord-015569-vy49r1zd 732 13 the the DT cord-015569-vy49r1zd 732 14 latter latter JJ cord-015569-vy49r1zd 732 15 converts convert VBZ cord-015569-vy49r1zd 732 16 these these DT cord-015569-vy49r1zd 732 17 distances distance NNS cord-015569-vy49r1zd 732 18 into into IN cord-015569-vy49r1zd 732 19 glomerular glomerular JJ cord-015569-vy49r1zd 732 20 activity activity NN cord-015569-vy49r1zd 732 21 patterns pattern NNS cord-015569-vy49r1zd 732 22 . . . cord-015569-vy49r1zd 733 1 However however RB cord-015569-vy49r1zd 733 2 , , , cord-015569-vy49r1zd 733 3 a a DT cord-015569-vy49r1zd 733 4 number number NN cord-015569-vy49r1zd 733 5 of of IN cord-015569-vy49r1zd 733 6 parameters parameter NNS cord-015569-vy49r1zd 733 7 included include VBN cord-015569-vy49r1zd 733 8 in in IN cord-015569-vy49r1zd 733 9 the the DT cord-015569-vy49r1zd 733 10 model model NN cord-015569-vy49r1zd 733 11 required require VBN cord-015569-vy49r1zd 733 12 further further JJ cord-015569-vy49r1zd 733 13 discussion discussion NN cord-015569-vy49r1zd 733 14 . . . cord-015569-vy49r1zd 734 1 We -PRON- PRP cord-015569-vy49r1zd 734 2 therefore therefore RB cord-015569-vy49r1zd 734 3 explored explore VBD cord-015569-vy49r1zd 734 4 the the DT cord-015569-vy49r1zd 734 5 two two CD cord-015569-vy49r1zd 734 6 parameters parameter NNS cord-015569-vy49r1zd 734 7 that that WDT cord-015569-vy49r1zd 734 8 most most RBS cord-015569-vy49r1zd 734 9 significantly significantly RB cord-015569-vy49r1zd 734 10 influenced influence VBD cord-015569-vy49r1zd 734 11 the the DT cord-015569-vy49r1zd 734 12 prediction prediction NN cord-015569-vy49r1zd 734 13 accuracy accuracy NN cord-015569-vy49r1zd 734 14 of of IN cord-015569-vy49r1zd 734 15 the the DT cord-015569-vy49r1zd 734 16 model model NN cord-015569-vy49r1zd 734 17 . . . cord-015569-vy49r1zd 735 1 These these DT cord-015569-vy49r1zd 735 2 were be VBD cord-015569-vy49r1zd 735 3 the the DT cord-015569-vy49r1zd 735 4 number number NN cord-015569-vy49r1zd 735 5 of of IN cord-015569-vy49r1zd 735 6 the the DT cord-015569-vy49r1zd 735 7 Gaussian gaussian JJ cord-015569-vy49r1zd 735 8 units unit NNS cord-015569-vy49r1zd 735 9 and and CC cord-015569-vy49r1zd 735 10 the the DT cord-015569-vy49r1zd 735 11 number number NN cord-015569-vy49r1zd 735 12 of of IN cord-015569-vy49r1zd 735 13 neuron neuron NN cord-015569-vy49r1zd 735 14 units unit NNS cord-015569-vy49r1zd 735 15 in in IN cord-015569-vy49r1zd 735 16 the the DT cord-015569-vy49r1zd 735 17 neural neural JJ cord-015569-vy49r1zd 735 18 network network NN cord-015569-vy49r1zd 735 19 . . . cord-015569-vy49r1zd 736 1 The the DT cord-015569-vy49r1zd 736 2 results result NNS cord-015569-vy49r1zd 736 3 indicated indicate VBD cord-015569-vy49r1zd 736 4 that that IN cord-015569-vy49r1zd 736 5 optimal optimal JJ cord-015569-vy49r1zd 736 6 prediction prediction NN cord-015569-vy49r1zd 736 7 ability ability NN cord-015569-vy49r1zd 736 8 was be VBD cord-015569-vy49r1zd 736 9 achieved achieve VBN cord-015569-vy49r1zd 736 10 when when WRB cord-015569-vy49r1zd 736 11 the the DT cord-015569-vy49r1zd 736 12 number number NN cord-015569-vy49r1zd 736 13 of of IN cord-015569-vy49r1zd 736 14 the the DT cord-015569-vy49r1zd 736 15 Gaussian gaussian JJ cord-015569-vy49r1zd 736 16 units unit NNS cord-015569-vy49r1zd 736 17 was be VBD cord-015569-vy49r1zd 736 18 approximately approximately RB cord-015569-vy49r1zd 736 19 sixty sixty CD cord-015569-vy49r1zd 736 20 and and CC cord-015569-vy49r1zd 736 21 the the DT cord-015569-vy49r1zd 736 22 number number NN cord-015569-vy49r1zd 736 23 of of IN cord-015569-vy49r1zd 736 24 neuron neuron NN cord-015569-vy49r1zd 736 25 units unit NNS cord-015569-vy49r1zd 736 26 in in IN cord-015569-vy49r1zd 736 27 the the DT cord-015569-vy49r1zd 736 28 hidden hidden JJ cord-015569-vy49r1zd 736 29 layer layer NN cord-015569-vy49r1zd 736 30 was be VBD cord-015569-vy49r1zd 736 31 approximately approximately RB cord-015569-vy49r1zd 736 32 double double JJ cord-015569-vy49r1zd 736 33 than than IN cord-015569-vy49r1zd 736 34 in in IN cord-015569-vy49r1zd 736 35 the the DT cord-015569-vy49r1zd 736 36 input input NN cord-015569-vy49r1zd 736 37 layer layer NN cord-015569-vy49r1zd 736 38 . . . cord-015569-vy49r1zd 737 1 Based base VBN cord-015569-vy49r1zd 737 2 on on IN cord-015569-vy49r1zd 737 3 these these DT cord-015569-vy49r1zd 737 4 outcomes outcome NNS cord-015569-vy49r1zd 737 5 , , , cord-015569-vy49r1zd 737 6 future future JJ cord-015569-vy49r1zd 737 7 plans plan NNS cord-015569-vy49r1zd 737 8 for for IN cord-015569-vy49r1zd 737 9 further further JJ cord-015569-vy49r1zd 737 10 improvement improvement NN cord-015569-vy49r1zd 737 11 of of IN cord-015569-vy49r1zd 737 12 prediction prediction NN cord-015569-vy49r1zd 737 13 ability ability NN cord-015569-vy49r1zd 737 14 were be VBD cord-015569-vy49r1zd 737 15 discussed discuss VBN cord-015569-vy49r1zd 737 16 . . . cord-015569-vy49r1zd 738 1 In in IN cord-015569-vy49r1zd 738 2 food food NN cord-015569-vy49r1zd 738 3 and and CC cord-015569-vy49r1zd 738 4 beverage beverage NN cord-015569-vy49r1zd 738 5 industries industry NNS cord-015569-vy49r1zd 738 6 , , , cord-015569-vy49r1zd 738 7 quantitative quantitative JJ cord-015569-vy49r1zd 738 8 assessment assessment NN cord-015569-vy49r1zd 738 9 of of IN cord-015569-vy49r1zd 738 10 odors odor NNS cord-015569-vy49r1zd 738 11 is be VBZ cord-015569-vy49r1zd 738 12 an an DT cord-015569-vy49r1zd 738 13 important important JJ cord-015569-vy49r1zd 738 14 process process NN cord-015569-vy49r1zd 738 15 in in IN cord-015569-vy49r1zd 738 16 developing develop VBG cord-015569-vy49r1zd 738 17 new new JJ cord-015569-vy49r1zd 738 18 products product NNS cord-015569-vy49r1zd 738 19 . . . cord-015569-vy49r1zd 739 1 However however RB cord-015569-vy49r1zd 739 2 , , , cord-015569-vy49r1zd 739 3 conventional conventional JJ cord-015569-vy49r1zd 739 4 odor odor NN cord-015569-vy49r1zd 739 5 sensing sense VBG cord-015569-vy49r1zd 739 6 systems system NNS cord-015569-vy49r1zd 739 7 focus focus VBP cord-015569-vy49r1zd 739 8 on on IN cord-015569-vy49r1zd 739 9 identifying identify VBG cord-015569-vy49r1zd 739 10 or or CC cord-015569-vy49r1zd 739 11 detecting detect VBG cord-015569-vy49r1zd 739 12 specific specific JJ cord-015569-vy49r1zd 739 13 odors odor NNS cord-015569-vy49r1zd 739 14 , , , cord-015569-vy49r1zd 739 15 and and CC cord-015569-vy49r1zd 739 16 are be VBP cord-015569-vy49r1zd 739 17 unable unable JJ cord-015569-vy49r1zd 739 18 to to TO cord-015569-vy49r1zd 739 19 assess assess VB cord-015569-vy49r1zd 739 20 odor odor NN cord-015569-vy49r1zd 739 21 qualities quality NNS cord-015569-vy49r1zd 739 22 perceived perceive VBN cord-015569-vy49r1zd 739 23 by by IN cord-015569-vy49r1zd 739 24 humans human NNS cord-015569-vy49r1zd 739 25 . . . cord-015569-vy49r1zd 740 1 Against against IN cord-015569-vy49r1zd 740 2 this this DT cord-015569-vy49r1zd 740 3 background background NN cord-015569-vy49r1zd 740 4 , , , cord-015569-vy49r1zd 740 5 our -PRON- PRP$ cord-015569-vy49r1zd 740 6 study study NN cord-015569-vy49r1zd 740 7 aims aim VBZ cord-015569-vy49r1zd 740 8 to to TO cord-015569-vy49r1zd 740 9 develop develop VB cord-015569-vy49r1zd 740 10 an an DT cord-015569-vy49r1zd 740 11 odor odor NN cord-015569-vy49r1zd 740 12 assessment assessment NN cord-015569-vy49r1zd 740 13 system system NN cord-015569-vy49r1zd 740 14 that that WDT cord-015569-vy49r1zd 740 15 can can MD cord-015569-vy49r1zd 740 16 be be VB cord-015569-vy49r1zd 740 17 used use VBN cord-015569-vy49r1zd 740 18 to to TO cord-015569-vy49r1zd 740 19 evaluate evaluate VB cord-015569-vy49r1zd 740 20 odors odor NNS cord-015569-vy49r1zd 740 21 and and CC cord-015569-vy49r1zd 740 22 support support VB cord-015569-vy49r1zd 740 23 sensory sensory JJ cord-015569-vy49r1zd 740 24 testing testing NN cord-015569-vy49r1zd 740 25 . . . cord-015569-vy49r1zd 741 1 Toward toward IN cord-015569-vy49r1zd 741 2 the the DT cord-015569-vy49r1zd 741 3 development development NN cord-015569-vy49r1zd 741 4 of of IN cord-015569-vy49r1zd 741 5 a a DT cord-015569-vy49r1zd 741 6 model model NN cord-015569-vy49r1zd 741 7 for for IN cord-015569-vy49r1zd 741 8 the the DT cord-015569-vy49r1zd 741 9 evaluation evaluation NN cord-015569-vy49r1zd 741 10 of of IN cord-015569-vy49r1zd 741 11 odor odor NN cord-015569-vy49r1zd 741 12 qualities quality NNS cord-015569-vy49r1zd 741 13 , , , cord-015569-vy49r1zd 741 14 this this DT cord-015569-vy49r1zd 741 15 study study NN cord-015569-vy49r1zd 741 16 focuses focus VBZ cord-015569-vy49r1zd 741 17 on on IN cord-015569-vy49r1zd 741 18 neural neural JJ cord-015569-vy49r1zd 741 19 activity activity NN cord-015569-vy49r1zd 741 20 evoked evoke VBN cord-015569-vy49r1zd 741 21 by by IN cord-015569-vy49r1zd 741 22 odorant odorant NN cord-015569-vy49r1zd 741 23 stimuli stimulus NNS cord-015569-vy49r1zd 741 24 in in IN cord-015569-vy49r1zd 741 25 the the DT cord-015569-vy49r1zd 741 26 olfactory olfactory JJ cord-015569-vy49r1zd 741 27 system system NN cord-015569-vy49r1zd 741 28 . . . cord-015569-vy49r1zd 742 1 This this DT cord-015569-vy49r1zd 742 2 is be VBZ cord-015569-vy49r1zd 742 3 because because IN cord-015569-vy49r1zd 742 4 the the DT cord-015569-vy49r1zd 742 5 results result NNS cord-015569-vy49r1zd 742 6 of of IN cord-015569-vy49r1zd 742 7 previous previous JJ cord-015569-vy49r1zd 742 8 studies study NNS cord-015569-vy49r1zd 742 9 suggested suggest VBD cord-015569-vy49r1zd 742 10 that that IN cord-015569-vy49r1zd 742 11 odorants odorant NNS cord-015569-vy49r1zd 742 12 prompting prompt VBG cord-015569-vy49r1zd 742 13 common common JJ cord-015569-vy49r1zd 742 14 neural neural JJ cord-015569-vy49r1zd 742 15 activity activity NN cord-015569-vy49r1zd 742 16 patterns pattern NNS cord-015569-vy49r1zd 742 17 in in IN cord-015569-vy49r1zd 742 18 the the DT cord-015569-vy49r1zd 742 19 olfactory olfactory JJ cord-015569-vy49r1zd 742 20 system system NN cord-015569-vy49r1zd 742 21 had have VBD cord-015569-vy49r1zd 742 22 similar similar JJ cord-015569-vy49r1zd 742 23 odorant odorant NN cord-015569-vy49r1zd 742 24 qualities quality NNS cord-015569-vy49r1zd 742 25 . . . cord-015569-vy49r1zd 743 1 As as IN cord-015569-vy49r1zd 743 2 a a DT cord-015569-vy49r1zd 743 3 first first JJ cord-015569-vy49r1zd 743 4 step step NN cord-015569-vy49r1zd 743 5 , , , cord-015569-vy49r1zd 743 6 we -PRON- PRP cord-015569-vy49r1zd 743 7 conducted conduct VBD cord-015569-vy49r1zd 743 8 a a DT cord-015569-vy49r1zd 743 9 series series NN cord-015569-vy49r1zd 743 10 of of IN cord-015569-vy49r1zd 743 11 human human JJ cord-015569-vy49r1zd 743 12 sensory sensory JJ cord-015569-vy49r1zd 743 13 tests test NNS cord-015569-vy49r1zd 743 14 to to TO cord-015569-vy49r1zd 743 15 investigate investigate VB cord-015569-vy49r1zd 743 16 perceptual perceptual JJ cord-015569-vy49r1zd 743 17 similarities similarity NNS cord-015569-vy49r1zd 743 18 between between IN cord-015569-vy49r1zd 743 19 odorants odorant NNS cord-015569-vy49r1zd 743 20 , , , cord-015569-vy49r1zd 743 21 and and CC cord-015569-vy49r1zd 743 22 then then RB cord-015569-vy49r1zd 743 23 compared compare VBD cord-015569-vy49r1zd 743 24 the the DT cord-015569-vy49r1zd 743 25 results result NNS cord-015569-vy49r1zd 743 26 with with IN cord-015569-vy49r1zd 743 27 activity activity NN cord-015569-vy49r1zd 743 28 patterns pattern NNS cord-015569-vy49r1zd 743 29 evoked evoke VBN cord-015569-vy49r1zd 743 30 on on IN cord-015569-vy49r1zd 743 31 the the DT cord-015569-vy49r1zd 743 32 glomerular glomerular JJ cord-015569-vy49r1zd 743 33 layer layer NN cord-015569-vy49r1zd 743 34 of of IN cord-015569-vy49r1zd 743 35 the the DT cord-015569-vy49r1zd 743 36 olfactory olfactory JJ cord-015569-vy49r1zd 743 37 bulb bulb NN cord-015569-vy49r1zd 743 38 in in IN cord-015569-vy49r1zd 743 39 rats rat NNS cord-015569-vy49r1zd 743 40 . . . cord-015569-vy49r1zd 744 1 These these DT cord-015569-vy49r1zd 744 2 animals animal NNS cord-015569-vy49r1zd 744 3 were be VBD cord-015569-vy49r1zd 744 4 chosen choose VBN cord-015569-vy49r1zd 744 5 because because IN cord-015569-vy49r1zd 744 6 the the DT cord-015569-vy49r1zd 744 7 structure structure NN cord-015569-vy49r1zd 744 8 of of IN cord-015569-vy49r1zd 744 9 their -PRON- PRP$ cord-015569-vy49r1zd 744 10 olfactory olfactory JJ cord-015569-vy49r1zd 744 11 system system NN cord-015569-vy49r1zd 744 12 is be VBZ cord-015569-vy49r1zd 744 13 similar similar JJ cord-015569-vy49r1zd 744 14 to to IN cord-015569-vy49r1zd 744 15 that that DT cord-015569-vy49r1zd 744 16 of of IN cord-015569-vy49r1zd 744 17 humans human NNS cord-015569-vy49r1zd 744 18 , , , cord-015569-vy49r1zd 744 19 and and CC cord-015569-vy49r1zd 744 20 measurement measurement NN cord-015569-vy49r1zd 744 21 data datum NNS cord-015569-vy49r1zd 744 22 relating relate VBG cord-015569-vy49r1zd 744 23 to to IN cord-015569-vy49r1zd 744 24 their -PRON- PRP$ cord-015569-vy49r1zd 744 25 glomerular glomerular JJ cord-015569-vy49r1zd 744 26 activity activity NN cord-015569-vy49r1zd 744 27 is be VBZ cord-015569-vy49r1zd 744 28 available available JJ cord-015569-vy49r1zd 744 29 online online RB cord-015569-vy49r1zd 744 30 . . . cord-015569-vy49r1zd 745 1 We -PRON- PRP cord-015569-vy49r1zd 745 2 defined define VBD cord-015569-vy49r1zd 745 3 three three CD cord-015569-vy49r1zd 745 4 indices index NNS cord-015569-vy49r1zd 745 5 ( ( -LRB- cord-015569-vy49r1zd 745 6 correlation correlation NN cord-015569-vy49r1zd 745 7 , , , cord-015569-vy49r1zd 745 8 overlap overlap VBP cord-015569-vy49r1zd 745 9 rate rate NN cord-015569-vy49r1zd 745 10 of of IN cord-015569-vy49r1zd 745 11 activation activation NN cord-015569-vy49r1zd 745 12 , , , cord-015569-vy49r1zd 745 13 and and CC cord-015569-vy49r1zd 745 14 sum sum NN cord-015569-vy49r1zd 745 15 of of IN cord-015569-vy49r1zd 745 16 squares square NNS cord-015569-vy49r1zd 745 17 of of IN cord-015569-vy49r1zd 745 18 difference difference NN cord-015569-vy49r1zd 745 19 between between IN cord-015569-vy49r1zd 745 20 histograms histogram NNS cord-015569-vy49r1zd 745 21 ) ) -RRB- cord-015569-vy49r1zd 745 22 to to TO cord-015569-vy49r1zd 745 23 describe describe VB cord-015569-vy49r1zd 745 24 similarities similarity NNS cord-015569-vy49r1zd 745 25 and and CC cord-015569-vy49r1zd 745 26 differences difference NNS cord-015569-vy49r1zd 745 27 between between IN cord-015569-vy49r1zd 745 28 activity activity NN cord-015569-vy49r1zd 745 29 patterns pattern NNS cord-015569-vy49r1zd 745 30 , , , cord-015569-vy49r1zd 745 31 and and CC cord-015569-vy49r1zd 745 32 also also RB cord-015569-vy49r1zd 745 33 conducted conduct VBD cord-015569-vy49r1zd 745 34 sensory sensory JJ cord-015569-vy49r1zd 745 35 testing testing NN cord-015569-vy49r1zd 745 36 to to TO cord-015569-vy49r1zd 745 37 determine determine VB cord-015569-vy49r1zd 745 38 similarities similarity NNS cord-015569-vy49r1zd 745 39 to to IN cord-015569-vy49r1zd 745 40 human human JJ cord-015569-vy49r1zd 745 41 perception perception NN cord-015569-vy49r1zd 745 42 . . . cord-015569-vy49r1zd 746 1 Comparison comparison NN cord-015569-vy49r1zd 746 2 of of IN cord-015569-vy49r1zd 746 3 the the DT cord-015569-vy49r1zd 746 4 results result NNS cord-015569-vy49r1zd 746 5 revealed reveal VBD cord-015569-vy49r1zd 746 6 that that IN cord-015569-vy49r1zd 746 7 each each DT cord-015569-vy49r1zd 746 8 index index NN cord-015569-vy49r1zd 746 9 showed show VBD cord-015569-vy49r1zd 746 10 a a DT cord-015569-vy49r1zd 746 11 weak weak JJ cord-015569-vy49r1zd 746 12 correlation correlation NN cord-015569-vy49r1zd 746 13 to to IN cord-015569-vy49r1zd 746 14 perceptual perceptual JJ cord-015569-vy49r1zd 746 15 similarities similarity NNS cord-015569-vy49r1zd 746 16 . . . cord-015569-vy49r1zd 747 1 We -PRON- PRP cord-015569-vy49r1zd 747 2 therefore therefore RB cord-015569-vy49r1zd 747 3 examined examine VBD cord-015569-vy49r1zd 747 4 whether whether IN cord-015569-vy49r1zd 747 5 similarities similarity NNS cord-015569-vy49r1zd 747 6 between between IN cord-015569-vy49r1zd 747 7 odorants odorant NNS cord-015569-vy49r1zd 747 8 could could MD cord-015569-vy49r1zd 747 9 be be VB cord-015569-vy49r1zd 747 10 predicted predict VBN cord-015569-vy49r1zd 747 11 by by IN cord-015569-vy49r1zd 747 12 combining combine VBG cord-015569-vy49r1zd 747 13 the the DT cord-015569-vy49r1zd 747 14 three three CD cord-015569-vy49r1zd 747 15 indices index NNS cord-015569-vy49r1zd 747 16 using use VBG cord-015569-vy49r1zd 747 17 SVM SVM NNP cord-015569-vy49r1zd 747 18 ( ( -LRB- cord-015569-vy49r1zd 747 19 Support Support NNP cord-015569-vy49r1zd 747 20 Vector Vector NNP cord-015569-vy49r1zd 747 21 Machine Machine NNP cord-015569-vy49r1zd 747 22 ) ) -RRB- cord-015569-vy49r1zd 747 23 , , , cord-015569-vy49r1zd 747 24 and and CC cord-015569-vy49r1zd 747 25 the the DT cord-015569-vy49r1zd 747 26 results result NNS cord-015569-vy49r1zd 747 27 indicated indicate VBD cord-015569-vy49r1zd 747 28 a a DT cord-015569-vy49r1zd 747 29 certain certain JJ cord-015569-vy49r1zd 747 30 level level NN cord-015569-vy49r1zd 747 31 of of IN cord-015569-vy49r1zd 747 32 prediction prediction NN cord-015569-vy49r1zd 747 33 ability ability NN cord-015569-vy49r1zd 747 34 . . . cord-015569-vy49r1zd 748 1 Novel novel JJ cord-015569-vy49r1zd 748 2 esters ester NNS cord-015569-vy49r1zd 748 3 , , , cord-015569-vy49r1zd 748 4 alcohols alcohol NNS cord-015569-vy49r1zd 748 5 , , , cord-015569-vy49r1zd 748 6 and and CC cord-015569-vy49r1zd 748 7 ethers ether NNS cord-015569-vy49r1zd 748 8 containing contain VBG cord-015569-vy49r1zd 748 9 a a DT cord-015569-vy49r1zd 748 10 tetrahydropyran tetrahydropyran NN cord-015569-vy49r1zd 748 11 ring ring NN cord-015569-vy49r1zd 748 12 were be VBD cord-015569-vy49r1zd 748 13 derived derive VBN cord-015569-vy49r1zd 748 14 from from IN cord-015569-vy49r1zd 748 15 ( ( -LRB- cord-015569-vy49r1zd 748 16 2,6,6-trimethyltetrahydropyran-2-yl)acetic 2,6,6-trimethyltetrahydropyran-2-yl)acetic JJ cord-015569-vy49r1zd 748 17 acid acid NN cord-015569-vy49r1zd 748 18 ( ( -LRB- cord-015569-vy49r1zd 748 19 1 1 CD cord-015569-vy49r1zd 748 20 ) ) -RRB- cord-015569-vy49r1zd 748 21 or or CC cord-015569-vy49r1zd 748 22 2-methyl-(2,6,6-trimethyltetra 2-methyl-(2,6,6-trimethyltetra CD cord-015569-vy49r1zd 748 23 - - HYPH cord-015569-vy49r1zd 748 24 hydropyran-2-yl)propanoic hydropyran-2-yl)propanoic NN cord-015569-vy49r1zd 748 25 acid acid NN cord-015569-vy49r1zd 748 26 ( ( -LRB- cord-015569-vy49r1zd 748 27 2 2 CD cord-015569-vy49r1zd 748 28 ) ) -RRB- cord-015569-vy49r1zd 748 29 , , , cord-015569-vy49r1zd 748 30 and and CC cord-015569-vy49r1zd 748 31 their -PRON- PRP$ cord-015569-vy49r1zd 748 32 odor odor NN cord-015569-vy49r1zd 748 33 properties property NNS cord-015569-vy49r1zd 748 34 were be VBD cord-015569-vy49r1zd 748 35 investigated investigate VBN cord-015569-vy49r1zd 748 36 . . . cord-015569-vy49r1zd 749 1 The the DT cord-015569-vy49r1zd 749 2 relationships relationship NNS cord-015569-vy49r1zd 749 3 between between IN cord-015569-vy49r1zd 749 4 the the DT cord-015569-vy49r1zd 749 5 structures structure NNS cord-015569-vy49r1zd 749 6 of of IN cord-015569-vy49r1zd 749 7 the the DT cord-015569-vy49r1zd 749 8 derived derive VBN cord-015569-vy49r1zd 749 9 compounds compound NNS cord-015569-vy49r1zd 749 10 and and CC cord-015569-vy49r1zd 749 11 their -PRON- PRP$ cord-015569-vy49r1zd 749 12 odor odor NN cord-015569-vy49r1zd 749 13 properties property NNS cord-015569-vy49r1zd 749 14 were be VBD cord-015569-vy49r1zd 749 15 also also RB cord-015569-vy49r1zd 749 16 examined examine VBN cord-015569-vy49r1zd 749 17 . . . cord-015569-vy49r1zd 750 1 The the DT cord-015569-vy49r1zd 750 2 methyl methyl NN cord-015569-vy49r1zd 750 3 ester ester NN cord-015569-vy49r1zd 750 4 of of IN cord-015569-vy49r1zd 750 5 carboxylic carboxylic JJ cord-015569-vy49r1zd 750 6 acid acid NN cord-015569-vy49r1zd 750 7 ( ( -LRB- cord-015569-vy49r1zd 750 8 1 1 CD cord-015569-vy49r1zd 750 9 ) ) -RRB- cord-015569-vy49r1zd 750 10 had have VBD cord-015569-vy49r1zd 750 11 a a DT cord-015569-vy49r1zd 750 12 refreshing refreshing JJ cord-015569-vy49r1zd 750 13 , , , cord-015569-vy49r1zd 750 14 floral floral JJ cord-015569-vy49r1zd 750 15 , , , cord-015569-vy49r1zd 750 16 and and CC cord-015569-vy49r1zd 750 17 herbaceous herbaceous JJ cord-015569-vy49r1zd 750 18 odor odor NN cord-015569-vy49r1zd 750 19 , , , cord-015569-vy49r1zd 750 20 and and CC cord-015569-vy49r1zd 750 21 the the DT cord-015569-vy49r1zd 750 22 methyl methyl NN cord-015569-vy49r1zd 750 23 ester ester NN cord-015569-vy49r1zd 750 24 of of IN cord-015569-vy49r1zd 750 25 carboxylic carboxylic JJ cord-015569-vy49r1zd 750 26 acid acid NN cord-015569-vy49r1zd 750 27 ( ( -LRB- cord-015569-vy49r1zd 750 28 2 2 CD cord-015569-vy49r1zd 750 29 ) ) -RRB- cord-015569-vy49r1zd 750 30 had have VBD cord-015569-vy49r1zd 750 31 a a DT cord-015569-vy49r1zd 750 32 refreshing refreshing JJ cord-015569-vy49r1zd 750 33 , , , cord-015569-vy49r1zd 750 34 woody woody JJ cord-015569-vy49r1zd 750 35 odor odor NN cord-015569-vy49r1zd 750 36 . . . cord-015569-vy49r1zd 751 1 The the DT cord-015569-vy49r1zd 751 2 propyl propyl NN cord-015569-vy49r1zd 751 3 ester ester NN cord-015569-vy49r1zd 751 4 of of IN cord-015569-vy49r1zd 751 5 carboxylic carboxylic JJ cord-015569-vy49r1zd 751 6 acid acid NN cord-015569-vy49r1zd 751 7 ( ( -LRB- cord-015569-vy49r1zd 751 8 1 1 CD cord-015569-vy49r1zd 751 9 ) ) -RRB- cord-015569-vy49r1zd 751 10 had have VBD cord-015569-vy49r1zd 751 11 an an DT cord-015569-vy49r1zd 751 12 adzuki adzuki NN cord-015569-vy49r1zd 751 13 - - HYPH cord-015569-vy49r1zd 751 14 bean bean NN cord-015569-vy49r1zd 751 15 odor odor NN cord-015569-vy49r1zd 751 16 , , , cord-015569-vy49r1zd 751 17 and and CC cord-015569-vy49r1zd 751 18 the the DT cord-015569-vy49r1zd 751 19 propyl propyl NN cord-015569-vy49r1zd 751 20 ester ester NN cord-015569-vy49r1zd 751 21 of of IN cord-015569-vy49r1zd 751 22 carboxylic carboxylic JJ cord-015569-vy49r1zd 751 23 acid acid NN cord-015569-vy49r1zd 751 24 ( ( -LRB- cord-015569-vy49r1zd 751 25 2 2 CD cord-015569-vy49r1zd 751 26 ) ) -RRB- cord-015569-vy49r1zd 751 27 had have VBD cord-015569-vy49r1zd 751 28 a a DT cord-015569-vy49r1zd 751 29 vegetable vegetable NN cord-015569-vy49r1zd 751 30 and and CC cord-015569-vy49r1zd 751 31 spicy spicy JJ cord-015569-vy49r1zd 751 32 odor odor NN cord-015569-vy49r1zd 751 33 . . . cord-015569-vy49r1zd 752 1 Thus thus RB cord-015569-vy49r1zd 752 2 , , , cord-015569-vy49r1zd 752 3 the the DT cord-015569-vy49r1zd 752 4 odor odor NN cord-015569-vy49r1zd 752 5 of of IN cord-015569-vy49r1zd 752 6 methyl methyl NN cord-015569-vy49r1zd 752 7 ester ester NN cord-015569-vy49r1zd 752 8 of of IN cord-015569-vy49r1zd 752 9 carboxylic carboxylic JJ cord-015569-vy49r1zd 752 10 acid acid NN cord-015569-vy49r1zd 752 11 ( ( -LRB- cord-015569-vy49r1zd 752 12 1 1 CD cord-015569-vy49r1zd 752 13 ) ) -RRB- cord-015569-vy49r1zd 752 14 was be VBD cord-015569-vy49r1zd 752 15 thus thus RB cord-015569-vy49r1zd 752 16 similar similar JJ cord-015569-vy49r1zd 752 17 to to IN cord-015569-vy49r1zd 752 18 that that DT cord-015569-vy49r1zd 752 19 of of IN cord-015569-vy49r1zd 752 20 methyl methyl NN cord-015569-vy49r1zd 752 21 ester ester NN cord-015569-vy49r1zd 752 22 of of IN cord-015569-vy49r1zd 752 23 carboxylic carboxylic JJ cord-015569-vy49r1zd 752 24 acid acid NN cord-015569-vy49r1zd 752 25 ( ( -LRB- cord-015569-vy49r1zd 752 26 2 2 CD cord-015569-vy49r1zd 752 27 ) ) -RRB- cord-015569-vy49r1zd 752 28 , , , cord-015569-vy49r1zd 752 29 but but CC cord-015569-vy49r1zd 752 30 considerably considerably RB cord-015569-vy49r1zd 752 31 different different JJ cord-015569-vy49r1zd 752 32 from from IN cord-015569-vy49r1zd 752 33 that that DT cord-015569-vy49r1zd 752 34 of of IN cord-015569-vy49r1zd 752 35 the the DT cord-015569-vy49r1zd 752 36 propyl propyl NN cord-015569-vy49r1zd 752 37 ester ester NN cord-015569-vy49r1zd 752 38 . . . cord-015569-vy49r1zd 753 1 Moreover moreover RB cord-015569-vy49r1zd 753 2 , , , cord-015569-vy49r1zd 753 3 the the DT cord-015569-vy49r1zd 753 4 odor odor NN cord-015569-vy49r1zd 753 5 of of IN cord-015569-vy49r1zd 753 6 propyl propyl NN cord-015569-vy49r1zd 753 7 ester ester NN cord-015569-vy49r1zd 753 8 of of IN cord-015569-vy49r1zd 753 9 carboxylic carboxylic JJ cord-015569-vy49r1zd 753 10 acid acid NN cord-015569-vy49r1zd 753 11 ( ( -LRB- cord-015569-vy49r1zd 753 12 1 1 CD cord-015569-vy49r1zd 753 13 ) ) -RRB- cord-015569-vy49r1zd 753 14 was be VBD cord-015569-vy49r1zd 753 15 considerably considerably RB cord-015569-vy49r1zd 753 16 different different JJ cord-015569-vy49r1zd 753 17 from from IN cord-015569-vy49r1zd 753 18 that that DT cord-015569-vy49r1zd 753 19 of of IN cord-015569-vy49r1zd 753 20 propyl propyl NN cord-015569-vy49r1zd 753 21 ester ester NN cord-015569-vy49r1zd 753 22 of of IN cord-015569-vy49r1zd 753 23 carboxylic carboxylic JJ cord-015569-vy49r1zd 753 24 acid acid NN cord-015569-vy49r1zd 753 25 ( ( -LRB- cord-015569-vy49r1zd 753 26 2 2 CD cord-015569-vy49r1zd 753 27 ) ) -RRB- cord-015569-vy49r1zd 753 28 . . . cord-015569-vy49r1zd 754 1 To to TO cord-015569-vy49r1zd 754 2 determine determine VB cord-015569-vy49r1zd 754 3 the the DT cord-015569-vy49r1zd 754 4 most most RBS cord-015569-vy49r1zd 754 5 stable stable JJ cord-015569-vy49r1zd 754 6 structures structure NNS cord-015569-vy49r1zd 754 7 of of IN cord-015569-vy49r1zd 754 8 these these DT cord-015569-vy49r1zd 754 9 esters ester NNS cord-015569-vy49r1zd 754 10 , , , cord-015569-vy49r1zd 754 11 the the DT cord-015569-vy49r1zd 754 12 molecular molecular JJ cord-015569-vy49r1zd 754 13 orbital orbital JJ cord-015569-vy49r1zd 754 14 calculation calculation NN cord-015569-vy49r1zd 754 15 was be VBD cord-015569-vy49r1zd 754 16 carried carry VBN cord-015569-vy49r1zd 754 17 out out RP cord-015569-vy49r1zd 754 18 for for IN cord-015569-vy49r1zd 754 19 each each DT cord-015569-vy49r1zd 754 20 ester ester NN cord-015569-vy49r1zd 754 21 using use VBG cord-015569-vy49r1zd 754 22 MOPAC MOPAC NNP cord-015569-vy49r1zd 754 23 PM3 PM3 NNPS cord-015569-vy49r1zd 754 24 . . . cord-015569-vy49r1zd 755 1 The the DT cord-015569-vy49r1zd 755 2 bulkiness bulkiness NN cord-015569-vy49r1zd 755 3 of of IN cord-015569-vy49r1zd 755 4 the the DT cord-015569-vy49r1zd 755 5 side side NN cord-015569-vy49r1zd 755 6 chain chain NN cord-015569-vy49r1zd 755 7 of of IN cord-015569-vy49r1zd 755 8 a a DT cord-015569-vy49r1zd 755 9 tetrahydropyran tetrahydropyran NN cord-015569-vy49r1zd 755 10 ring ring NN cord-015569-vy49r1zd 755 11 of of IN cord-015569-vy49r1zd 755 12 methyl methyl NN cord-015569-vy49r1zd 755 13 ester ester NN cord-015569-vy49r1zd 755 14 of of IN cord-015569-vy49r1zd 755 15 carboxylic carboxylic JJ cord-015569-vy49r1zd 755 16 acid acid NN cord-015569-vy49r1zd 755 17 ( ( -LRB- cord-015569-vy49r1zd 755 18 1 1 CD cord-015569-vy49r1zd 755 19 ) ) -RRB- cord-015569-vy49r1zd 755 20 was be VBD cord-015569-vy49r1zd 755 21 comparable comparable JJ cord-015569-vy49r1zd 755 22 to to IN cord-015569-vy49r1zd 755 23 that that DT cord-015569-vy49r1zd 755 24 of of IN cord-015569-vy49r1zd 755 25 methyl methyl NN cord-015569-vy49r1zd 755 26 ester ester NN cord-015569-vy49r1zd 755 27 of of IN cord-015569-vy49r1zd 755 28 carboxylic carboxylic JJ cord-015569-vy49r1zd 755 29 acid acid NN cord-015569-vy49r1zd 755 30 ( ( -LRB- cord-015569-vy49r1zd 755 31 2 2 CD cord-015569-vy49r1zd 755 32 ) ) -RRB- cord-015569-vy49r1zd 755 33 . . . cord-015569-vy49r1zd 756 1 However however RB cord-015569-vy49r1zd 756 2 , , , cord-015569-vy49r1zd 756 3 the the DT cord-015569-vy49r1zd 756 4 side side NN cord-015569-vy49r1zd 756 5 chain chain NN cord-015569-vy49r1zd 756 6 of of IN cord-015569-vy49r1zd 756 7 propyl propyl NN cord-015569-vy49r1zd 756 8 ester ester NN cord-015569-vy49r1zd 756 9 of of IN cord-015569-vy49r1zd 756 10 carboxylic carboxylic JJ cord-015569-vy49r1zd 756 11 acid acid NN cord-015569-vy49r1zd 756 12 ( ( -LRB- cord-015569-vy49r1zd 756 13 1 1 CD cord-015569-vy49r1zd 756 14 ) ) -RRB- cord-015569-vy49r1zd 756 15 was be VBD cord-015569-vy49r1zd 756 16 bulkier bulky JJR cord-015569-vy49r1zd 756 17 than than IN cord-015569-vy49r1zd 756 18 that that DT cord-015569-vy49r1zd 756 19 of of IN cord-015569-vy49r1zd 756 20 its -PRON- PRP$ cord-015569-vy49r1zd 756 21 methyl methyl NN cord-015569-vy49r1zd 756 22 ester ester NN cord-015569-vy49r1zd 756 23 , , , cord-015569-vy49r1zd 756 24 and and CC cord-015569-vy49r1zd 756 25 this this DT cord-015569-vy49r1zd 756 26 increased increase VBN cord-015569-vy49r1zd 756 27 bulkiness bulkiness NN cord-015569-vy49r1zd 756 28 prevents prevent VBZ cord-015569-vy49r1zd 756 29 the the DT cord-015569-vy49r1zd 756 30 free free JJ cord-015569-vy49r1zd 756 31 rotation rotation NN cord-015569-vy49r1zd 756 32 of of IN cord-015569-vy49r1zd 756 33 the the DT cord-015569-vy49r1zd 756 34 side side NN cord-015569-vy49r1zd 756 35 chain chain NN cord-015569-vy49r1zd 756 36 of of IN cord-015569-vy49r1zd 756 37 propyl propyl NNP cord-015569-vy49r1zd 756 38 ester ester NN cord-015569-vy49r1zd 756 39 . . . cord-015569-vy49r1zd 757 1 Similarly similarly RB cord-015569-vy49r1zd 757 2 , , , cord-015569-vy49r1zd 757 3 the the DT cord-015569-vy49r1zd 757 4 bulkiness bulkiness NN cord-015569-vy49r1zd 757 5 of of IN cord-015569-vy49r1zd 757 6 the the DT cord-015569-vy49r1zd 757 7 side side NN cord-015569-vy49r1zd 757 8 chain chain NN cord-015569-vy49r1zd 757 9 of of IN cord-015569-vy49r1zd 757 10 propyl propyl NN cord-015569-vy49r1zd 757 11 ester ester NN cord-015569-vy49r1zd 757 12 of of IN cord-015569-vy49r1zd 757 13 carboxylic carboxylic JJ cord-015569-vy49r1zd 757 14 acid acid NN cord-015569-vy49r1zd 757 15 ( ( -LRB- cord-015569-vy49r1zd 757 16 2 2 CD cord-015569-vy49r1zd 757 17 ) ) -RRB- cord-015569-vy49r1zd 757 18 makes make VBZ cord-015569-vy49r1zd 757 19 its -PRON- PRP$ cord-015569-vy49r1zd 757 20 free free JJ cord-015569-vy49r1zd 757 21 rotation rotation NN cord-015569-vy49r1zd 757 22 more more RBR cord-015569-vy49r1zd 757 23 difficult difficult JJ cord-015569-vy49r1zd 757 24 than than IN cord-015569-vy49r1zd 757 25 that that DT cord-015569-vy49r1zd 757 26 of of IN cord-015569-vy49r1zd 757 27 propyl propyl NN cord-015569-vy49r1zd 757 28 ester ester NN cord-015569-vy49r1zd 757 29 of of IN cord-015569-vy49r1zd 757 30 carboxylic carboxylic JJ cord-015569-vy49r1zd 757 31 acid acid NN cord-015569-vy49r1zd 757 32 ( ( -LRB- cord-015569-vy49r1zd 757 33 1 1 CD cord-015569-vy49r1zd 757 34 ) ) -RRB- cord-015569-vy49r1zd 757 35 . . . cord-015569-vy49r1zd 758 1 Thus thus RB cord-015569-vy49r1zd 758 2 , , , cord-015569-vy49r1zd 758 3 the the DT cord-015569-vy49r1zd 758 4 bulkiness bulkiness NN cord-015569-vy49r1zd 758 5 and and CC cord-015569-vy49r1zd 758 6 the the DT cord-015569-vy49r1zd 758 7 degree degree NN cord-015569-vy49r1zd 758 8 of of IN cord-015569-vy49r1zd 758 9 free free JJ cord-015569-vy49r1zd 758 10 rotation rotation NN cord-015569-vy49r1zd 758 11 of of IN cord-015569-vy49r1zd 758 12 the the DT cord-015569-vy49r1zd 758 13 side side NN cord-015569-vy49r1zd 758 14 chain chain NN cord-015569-vy49r1zd 758 15 of of IN cord-015569-vy49r1zd 758 16 a a DT cord-015569-vy49r1zd 758 17 tetrahydropyran tetrahydropyran NN cord-015569-vy49r1zd 758 18 ring ring NN cord-015569-vy49r1zd 758 19 influence influence NN cord-015569-vy49r1zd 758 20 the the DT cord-015569-vy49r1zd 758 21 odor odor NN cord-015569-vy49r1zd 758 22 of of IN cord-015569-vy49r1zd 758 23 compounds compound NNS cord-015569-vy49r1zd 758 24 containing contain VBG cord-015569-vy49r1zd 758 25 a a DT cord-015569-vy49r1zd 758 26 tetrahydropyran tetrahydropyran NN cord-015569-vy49r1zd 758 27 ring ring NN cord-015569-vy49r1zd 758 28 . . . cord-015569-vy49r1zd 759 1 Measured measure VBN cord-015569-vy49r1zd 759 2 odor odor NN cord-015569-vy49r1zd 759 3 thresholds threshold NNS cord-015569-vy49r1zd 759 4 depend depend VBP cord-015569-vy49r1zd 759 5 on on IN cord-015569-vy49r1zd 759 6 both both DT cord-015569-vy49r1zd 759 7 subject subject JJ cord-015569-vy49r1zd 759 8 sensitivity sensitivity NN cord-015569-vy49r1zd 759 9 and and CC cord-015569-vy49r1zd 759 10 method method NN cord-015569-vy49r1zd 759 11 . . . cord-015569-vy49r1zd 760 1 Yet yet RB cord-015569-vy49r1zd 760 2 , , , cord-015569-vy49r1zd 760 3 threshold threshold NN cord-015569-vy49r1zd 760 4 - - HYPH cord-015569-vy49r1zd 760 5 methods method NNS cord-015569-vy49r1zd 760 6 have have VBP cord-015569-vy49r1zd 760 7 received receive VBN cord-015569-vy49r1zd 760 8 relatively relatively RB cord-015569-vy49r1zd 760 9 little little JJ cord-015569-vy49r1zd 760 10 systematic systematic JJ cord-015569-vy49r1zd 760 11 attention attention NN cord-015569-vy49r1zd 760 12 in in IN cord-015569-vy49r1zd 760 13 olfaction olfaction NN cord-015569-vy49r1zd 760 14 . . . cord-015569-vy49r1zd 761 1 We -PRON- PRP cord-015569-vy49r1zd 761 2 measured measure VBD cord-015569-vy49r1zd 761 3 psychometric psychometric JJ cord-015569-vy49r1zd 761 4 , , , cord-015569-vy49r1zd 761 5 i.e. i.e. FW cord-015569-vy49r1zd 761 6 , , , cord-015569-vy49r1zd 761 7 proportion proportion NN cord-015569-vy49r1zd 761 8 correct correct JJ cord-015569-vy49r1zd 761 9 detection detection NN cord-015569-vy49r1zd 761 10 vs. vs. IN cord-015569-vy49r1zd 761 11 concentration concentration NN cord-015569-vy49r1zd 761 12 , , , cord-015569-vy49r1zd 761 13 functions function NNS cord-015569-vy49r1zd 761 14 for for IN cord-015569-vy49r1zd 761 15 acetic acetic JJ cord-015569-vy49r1zd 761 16 acid acid NN cord-015569-vy49r1zd 761 17 . . . cord-015569-vy49r1zd 762 1 A a DT cord-015569-vy49r1zd 762 2 2-outof-5 2-outof-5 CD cord-015569-vy49r1zd 762 3 , , , cord-015569-vy49r1zd 762 4 forced force VBN cord-015569-vy49r1zd 762 5 - - HYPH cord-015569-vy49r1zd 762 6 choice choice NN cord-015569-vy49r1zd 762 7 procedure procedure NN cord-015569-vy49r1zd 762 8 was be VBD cord-015569-vy49r1zd 762 9 used use VBN cord-015569-vy49r1zd 762 10 . . . cord-015569-vy49r1zd 763 1 Stimuli stimulus NNS cord-015569-vy49r1zd 763 2 were be VBD cord-015569-vy49r1zd 763 3 precisely precisely RB cord-015569-vy49r1zd 763 4 controlled control VBN cord-015569-vy49r1zd 763 5 using use VBG cord-015569-vy49r1zd 763 6 an an DT cord-015569-vy49r1zd 763 7 air air NN cord-015569-vy49r1zd 763 8 - - HYPH cord-015569-vy49r1zd 763 9 dilution dilution NN cord-015569-vy49r1zd 763 10 olfactometer olfactometer NN cord-015569-vy49r1zd 763 11 . . . cord-015569-vy49r1zd 764 1 The the DT cord-015569-vy49r1zd 764 2 design design NN cord-015569-vy49r1zd 764 3 had have VBD cord-015569-vy49r1zd 764 4 four four CD cord-015569-vy49r1zd 764 5 factors factor NNS cord-015569-vy49r1zd 764 6 , , , cord-015569-vy49r1zd 764 7 all all DT cord-015569-vy49r1zd 764 8 randomized randomized JJ cord-015569-vy49r1zd 764 9 or or CC cord-015569-vy49r1zd 764 10 counter counter JJ cord-015569-vy49r1zd 764 11 - - JJ cord-015569-vy49r1zd 764 12 balanced balanced JJ cord-015569-vy49r1zd 764 13 : : : cord-015569-vy49r1zd 764 14 1 1 LS cord-015569-vy49r1zd 764 15 ) ) -RRB- cord-015569-vy49r1zd 764 16 practiced practice VBD cord-015569-vy49r1zd 764 17 subjects subject NNS cord-015569-vy49r1zd 764 18 vs. vs. IN cord-015569-vy49r1zd 764 19 unpracticed unpracticed JJ cord-015569-vy49r1zd 764 20 subjects subject NNS cord-015569-vy49r1zd 764 21 ( ( -LRB- cord-015569-vy49r1zd 764 22 between between IN cord-015569-vy49r1zd 764 23 subjects subject NNS cord-015569-vy49r1zd 764 24 ) ) -RRB- cord-015569-vy49r1zd 764 25 ; ; : cord-015569-vy49r1zd 764 26 2 2 LS cord-015569-vy49r1zd 764 27 ) ) -RRB- cord-015569-vy49r1zd 764 28 15-second 15-second JJ cord-015569-vy49r1zd 764 29 inter inter JJ cord-015569-vy49r1zd 764 30 - - JJ cord-015569-vy49r1zd 764 31 trial trial JJ cord-015569-vy49r1zd 764 32 interval interval NN cord-015569-vy49r1zd 764 33 ( ( -LRB- cord-015569-vy49r1zd 764 34 ITI ITI NNP cord-015569-vy49r1zd 764 35 ) ) -RRB- cord-015569-vy49r1zd 764 36 vs. vs. NN cord-015569-vy49r1zd 764 37 30-second 30-second CD cord-015569-vy49r1zd 764 38 ITI ITI NNP cord-015569-vy49r1zd 764 39 ( ( -LRB- cord-015569-vy49r1zd 764 40 within within IN cord-015569-vy49r1zd 764 41 subjects subject NNS cord-015569-vy49r1zd 764 42 ) ) -RRB- cord-015569-vy49r1zd 764 43 ; ; : cord-015569-vy49r1zd 764 44 3 3 LS cord-015569-vy49r1zd 764 45 ) ) -RRB- cord-015569-vy49r1zd 764 46 re re NN cord-015569-vy49r1zd 764 47 - - NN cord-015569-vy49r1zd 764 48 sampling sampling NN cord-015569-vy49r1zd 764 49 allowed allow VBN cord-015569-vy49r1zd 764 50 ( ( -LRB- cord-015569-vy49r1zd 764 51 i.e. i.e. FW cord-015569-vy49r1zd 764 52 , , , cord-015569-vy49r1zd 764 53 subjects subject NNS cord-015569-vy49r1zd 764 54 could could MD cord-015569-vy49r1zd 764 55 smell smell VB cord-015569-vy49r1zd 764 56 each each DT cord-015569-vy49r1zd 764 57 of of IN cord-015569-vy49r1zd 764 58 the the DT cord-015569-vy49r1zd 764 59 5 5 CD cord-015569-vy49r1zd 764 60 stimuli stimulus NNS cord-015569-vy49r1zd 764 61 presented present VBN cord-015569-vy49r1zd 764 62 during during IN cord-015569-vy49r1zd 764 63 a a DT cord-015569-vy49r1zd 764 64 trial trial NN cord-015569-vy49r1zd 764 65 as as IN cord-015569-vy49r1zd 764 66 many many JJ cord-015569-vy49r1zd 764 67 times time NNS cord-015569-vy49r1zd 764 68 as as IN cord-015569-vy49r1zd 764 69 they -PRON- PRP cord-015569-vy49r1zd 764 70 wished wish VBD cord-015569-vy49r1zd 764 71 ) ) -RRB- cord-015569-vy49r1zd 764 72 vs. vs. CC cord-015569-vy49r1zd 764 73 not not RB cord-015569-vy49r1zd 764 74 allowed allow VBN cord-015569-vy49r1zd 764 75 ( ( -LRB- cord-015569-vy49r1zd 764 76 within within IN cord-015569-vy49r1zd 764 77 subjects subject NNS cord-015569-vy49r1zd 764 78 ) ) -RRB- cord-015569-vy49r1zd 764 79 ; ; : cord-015569-vy49r1zd 764 80 4 4 LS cord-015569-vy49r1zd 764 81 ) ) -RRB- cord-015569-vy49r1zd 764 82 concentrations concentration NNS cord-015569-vy49r1zd 764 83 presented present VBN cord-015569-vy49r1zd 764 84 in in IN cord-015569-vy49r1zd 764 85 ascending ascend VBG cord-015569-vy49r1zd 764 86 order order NN cord-015569-vy49r1zd 764 87 ( ( -LRB- cord-015569-vy49r1zd 764 88 lowest low JJS cord-015569-vy49r1zd 764 89 concentration concentration NN cord-015569-vy49r1zd 764 90 first first RB cord-015569-vy49r1zd 764 91 , , , cord-015569-vy49r1zd 764 92 moving move VBG cord-015569-vy49r1zd 764 93 up up RP cord-015569-vy49r1zd 764 94 to to IN cord-015569-vy49r1zd 764 95 the the DT cord-015569-vy49r1zd 764 96 highest high JJS cord-015569-vy49r1zd 764 97 concentration concentration NN cord-015569-vy49r1zd 764 98 , , , cord-015569-vy49r1zd 764 99 then then RB cord-015569-vy49r1zd 764 100 starting start VBG cord-015569-vy49r1zd 764 101 again again RB cord-015569-vy49r1zd 764 102 at at IN cord-015569-vy49r1zd 764 103 the the DT cord-015569-vy49r1zd 764 104 lowest low JJS cord-015569-vy49r1zd 764 105 concentration concentration NN cord-015569-vy49r1zd 764 106 after after IN cord-015569-vy49r1zd 764 107 a a DT cord-015569-vy49r1zd 764 108 break break NN cord-015569-vy49r1zd 764 109 ) ) -RRB- cord-015569-vy49r1zd 764 110 vs. vs. FW cord-015569-vy49r1zd 764 111 random random JJ cord-015569-vy49r1zd 764 112 order order NN cord-015569-vy49r1zd 764 113 ( ( -LRB- cord-015569-vy49r1zd 764 114 within within IN cord-015569-vy49r1zd 764 115 subjects subject NNS cord-015569-vy49r1zd 764 116 ) ) -RRB- cord-015569-vy49r1zd 764 117 . . . cord-015569-vy49r1zd 765 1 A a DT cord-015569-vy49r1zd 765 2 four four CD cord-015569-vy49r1zd 765 3 - - HYPH cord-015569-vy49r1zd 765 4 way way NN cord-015569-vy49r1zd 765 5 ANOVA ANOVA NNP cord-015569-vy49r1zd 765 6 ( ( -LRB- cord-015569-vy49r1zd 765 7 the the DT cord-015569-vy49r1zd 765 8 above above JJ cord-015569-vy49r1zd 765 9 four four CD cord-015569-vy49r1zd 765 10 factors factor NNS cord-015569-vy49r1zd 765 11 ) ) -RRB- cord-015569-vy49r1zd 765 12 revealed reveal VBD cord-015569-vy49r1zd 765 13 a a DT cord-015569-vy49r1zd 765 14 significant significant JJ cord-015569-vy49r1zd 765 15 main main JJ cord-015569-vy49r1zd 765 16 effect effect NN cord-015569-vy49r1zd 765 17 of of IN cord-015569-vy49r1zd 765 18 re re JJ cord-015569-vy49r1zd 765 19 - - JJ cord-015569-vy49r1zd 765 20 sample sample JJ cord-015569-vy49r1zd 765 21 condition condition NN cord-015569-vy49r1zd 765 22 . . . cord-015569-vy49r1zd 766 1 These these DT cord-015569-vy49r1zd 766 2 results result NNS cord-015569-vy49r1zd 766 3 highlight highlight VBP cord-015569-vy49r1zd 766 4 the the DT cord-015569-vy49r1zd 766 5 importance importance NN cord-015569-vy49r1zd 766 6 of of IN cord-015569-vy49r1zd 766 7 methods method NNS cord-015569-vy49r1zd 766 8 for for IN cord-015569-vy49r1zd 766 9 measured measure VBN cord-015569-vy49r1zd 766 10 thresholds threshold NNS cord-015569-vy49r1zd 766 11 , , , cord-015569-vy49r1zd 766 12 and and CC cord-015569-vy49r1zd 766 13 have have VBP cord-015569-vy49r1zd 766 14 implications implication NNS cord-015569-vy49r1zd 766 15 for for IN cord-015569-vy49r1zd 766 16 laboratory laboratory NN cord-015569-vy49r1zd 766 17 practice practice NN cord-015569-vy49r1zd 766 18 . . . cord-015569-vy49r1zd 767 1 Many many JJ cord-015569-vy49r1zd 767 2 researches research NNS cord-015569-vy49r1zd 767 3 have have VBP cord-015569-vy49r1zd 767 4 reported report VBN cord-015569-vy49r1zd 767 5 the the DT cord-015569-vy49r1zd 767 6 influence influence NN cord-015569-vy49r1zd 767 7 of of IN cord-015569-vy49r1zd 767 8 information information NN cord-015569-vy49r1zd 767 9 to to TO cord-015569-vy49r1zd 767 10 identify identify VB cord-015569-vy49r1zd 767 11 an an DT cord-015569-vy49r1zd 767 12 odor odor NN cord-015569-vy49r1zd 767 13 . . . cord-015569-vy49r1zd 768 1 We -PRON- PRP cord-015569-vy49r1zd 768 2 tried try VBD cord-015569-vy49r1zd 768 3 to to TO cord-015569-vy49r1zd 768 4 measure measure VB cord-015569-vy49r1zd 768 5 the the DT cord-015569-vy49r1zd 768 6 prefrontal prefrontal JJ cord-015569-vy49r1zd 768 7 cortex cortex NN cord-015569-vy49r1zd 768 8 activity activity NN cord-015569-vy49r1zd 768 9 during during IN cord-015569-vy49r1zd 768 10 the the DT cord-015569-vy49r1zd 768 11 smelling smell VBG cord-015569-vy49r1zd 768 12 an an DT cord-015569-vy49r1zd 768 13 odor odor NN cord-015569-vy49r1zd 768 14 using use VBG cord-015569-vy49r1zd 768 15 functional functional JJ cord-015569-vy49r1zd 768 16 near near JJ cord-015569-vy49r1zd 768 17 - - HYPH cord-015569-vy49r1zd 768 18 infrared infrared JJ cord-015569-vy49r1zd 768 19 spectroscopy spectroscopy NN cord-015569-vy49r1zd 768 20 ( ( -LRB- cord-015569-vy49r1zd 768 21 fNIRS fnirs NN cord-015569-vy49r1zd 768 22 ) ) -RRB- cord-015569-vy49r1zd 768 23 to to TO cord-015569-vy49r1zd 768 24 find find VB cord-015569-vy49r1zd 768 25 out out RP cord-015569-vy49r1zd 768 26 the the DT cord-015569-vy49r1zd 768 27 effects effect NNS cord-015569-vy49r1zd 768 28 of of IN cord-015569-vy49r1zd 768 29 positive positive JJ cord-015569-vy49r1zd 768 30 and and CC cord-015569-vy49r1zd 768 31 negative negative JJ cord-015569-vy49r1zd 768 32 information information NN cord-015569-vy49r1zd 768 33 with with IN cord-015569-vy49r1zd 768 34 a a DT cord-015569-vy49r1zd 768 35 same same JJ cord-015569-vy49r1zd 768 36 odor odor NN cord-015569-vy49r1zd 768 37 . . . cord-015569-vy49r1zd 769 1 We -PRON- PRP cord-015569-vy49r1zd 769 2 used use VBD cord-015569-vy49r1zd 769 3 three three CD cord-015569-vy49r1zd 769 4 kinds kind NNS cord-015569-vy49r1zd 769 5 of of IN cord-015569-vy49r1zd 769 6 odors odor NNS cord-015569-vy49r1zd 769 7 which which WDT cord-015569-vy49r1zd 769 8 have have VBP cord-015569-vy49r1zd 769 9 been be VBN cord-015569-vy49r1zd 769 10 evaluated evaluate VBN cord-015569-vy49r1zd 769 11 as as IN cord-015569-vy49r1zd 769 12 moderately moderately RB cord-015569-vy49r1zd 769 13 hedonic hedonic JJ cord-015569-vy49r1zd 769 14 values value NNS cord-015569-vy49r1zd 769 15 by by IN cord-015569-vy49r1zd 769 16 a a DT cord-015569-vy49r1zd 769 17 preliminary preliminary JJ cord-015569-vy49r1zd 769 18 experiment experiment NN cord-015569-vy49r1zd 769 19 . . . cord-015569-vy49r1zd 770 1 Eighteen eighteen CD cord-015569-vy49r1zd 770 2 subjects subject NNS cord-015569-vy49r1zd 770 3 who who WP cord-015569-vy49r1zd 770 4 had have VBD cord-015569-vy49r1zd 770 5 normal normal JJ cord-015569-vy49r1zd 770 6 sense sense NN cord-015569-vy49r1zd 770 7 of of IN cord-015569-vy49r1zd 770 8 odor odor NN cord-015569-vy49r1zd 770 9 were be VBD cord-015569-vy49r1zd 770 10 presented present VBN cord-015569-vy49r1zd 770 11 these these DT cord-015569-vy49r1zd 770 12 odors odor NNS cord-015569-vy49r1zd 770 13 with with IN cord-015569-vy49r1zd 770 14 visual visual JJ cord-015569-vy49r1zd 770 15 stimulation stimulation NN cord-015569-vy49r1zd 770 16 on on IN cord-015569-vy49r1zd 770 17 a a DT cord-015569-vy49r1zd 770 18 display display NN cord-015569-vy49r1zd 770 19 . . . cord-015569-vy49r1zd 771 1 The the DT cord-015569-vy49r1zd 771 2 visual visual JJ cord-015569-vy49r1zd 771 3 stimulation stimulation NN cord-015569-vy49r1zd 771 4 showed show VBD cord-015569-vy49r1zd 771 5 the the DT cord-015569-vy49r1zd 771 6 explanations explanation NNS cord-015569-vy49r1zd 771 7 of of IN cord-015569-vy49r1zd 771 8 each each DT cord-015569-vy49r1zd 771 9 odor odor NN cord-015569-vy49r1zd 771 10 with with IN cord-015569-vy49r1zd 771 11 positive positive JJ cord-015569-vy49r1zd 771 12 or or CC cord-015569-vy49r1zd 771 13 negative negative JJ cord-015569-vy49r1zd 771 14 information information NN cord-015569-vy49r1zd 771 15 . . . cord-015569-vy49r1zd 772 1 During during IN cord-015569-vy49r1zd 772 2 the the DT cord-015569-vy49r1zd 772 3 experiment experiment NN cord-015569-vy49r1zd 772 4 , , , cord-015569-vy49r1zd 772 5 subjects subject NNS cord-015569-vy49r1zd 772 6 were be VBD cord-015569-vy49r1zd 772 7 measured measure VBN cord-015569-vy49r1zd 772 8 for for IN cord-015569-vy49r1zd 772 9 their -PRON- PRP$ cord-015569-vy49r1zd 772 10 prefrontal prefrontal JJ cord-015569-vy49r1zd 772 11 cortex cortex NN cord-015569-vy49r1zd 772 12 activity activity NN cord-015569-vy49r1zd 772 13 with with IN cord-015569-vy49r1zd 772 14 42 42 CD cord-015569-vy49r1zd 772 15 channels channel NNS cord-015569-vy49r1zd 772 16 ( ( -LRB- cord-015569-vy49r1zd 772 17 3x9 3x9 CD cord-015569-vy49r1zd 772 18 distributions distribution NNS cord-015569-vy49r1zd 772 19 ) ) -RRB- cord-015569-vy49r1zd 772 20 by by IN cord-015569-vy49r1zd 772 21 fNIRS fnirs NN cord-015569-vy49r1zd 773 1 ( ( -LRB- cord-015569-vy49r1zd 773 2 FOIRE-3000 FOIRE-3000 NNP cord-015569-vy49r1zd 773 3 , , , cord-015569-vy49r1zd 773 4 Shimadzu Shimadzu NNP cord-015569-vy49r1zd 773 5 corp corp NNP cord-015569-vy49r1zd 773 6 ) ) -RRB- cord-015569-vy49r1zd 773 7 . . . cord-015569-vy49r1zd 774 1 These these DT cord-015569-vy49r1zd 774 2 odors odor NNS cord-015569-vy49r1zd 774 3 were be VBD cord-015569-vy49r1zd 774 4 presented present VBN cord-015569-vy49r1zd 774 5 by by IN cord-015569-vy49r1zd 774 6 odor odor NN cord-015569-vy49r1zd 774 7 - - HYPH cord-015569-vy49r1zd 774 8 stimulation stimulation NN cord-015569-vy49r1zd 774 9 system system NN cord-015569-vy49r1zd 774 10 through through IN cord-015569-vy49r1zd 774 11 tubes tube NNS cord-015569-vy49r1zd 774 12 and and CC cord-015569-vy49r1zd 774 13 a a DT cord-015569-vy49r1zd 774 14 mask mask NN cord-015569-vy49r1zd 774 15 . . . cord-015569-vy49r1zd 775 1 The the DT cord-015569-vy49r1zd 775 2 experiment experiment NN cord-015569-vy49r1zd 775 3 was be VBD cord-015569-vy49r1zd 775 4 conducted conduct VBN cord-015569-vy49r1zd 775 5 by by IN cord-015569-vy49r1zd 775 6 the the DT cord-015569-vy49r1zd 775 7 following follow VBG cord-015569-vy49r1zd 775 8 protocol protocol NN cord-015569-vy49r1zd 775 9 ; ; : cord-015569-vy49r1zd 775 10 pre pre JJ cord-015569-vy49r1zd 775 11 - - JJ cord-015569-vy49r1zd 775 12 resting resting JJ cord-015569-vy49r1zd 775 13 period period NN cord-015569-vy49r1zd 775 14 ( ( -LRB- cord-015569-vy49r1zd 775 15 20s 20 NNS cord-015569-vy49r1zd 775 16 ) ) -RRB- cord-015569-vy49r1zd 775 17 , , , cord-015569-vy49r1zd 775 18 task task NN cord-015569-vy49r1zd 775 19 period period NN cord-015569-vy49r1zd 775 20 ( ( -LRB- cord-015569-vy49r1zd 775 21 15s 15 NNS cord-015569-vy49r1zd 775 22 ) ) -RRB- cord-015569-vy49r1zd 775 23 , , , cord-015569-vy49r1zd 775 24 evaluation evaluation NN cord-015569-vy49r1zd 775 25 period period NN cord-015569-vy49r1zd 775 26 ( ( -LRB- cord-015569-vy49r1zd 775 27 25s 25s NNPS cord-015569-vy49r1zd 775 28 ) ) -RRB- cord-015569-vy49r1zd 775 29 and and CC cord-015569-vy49r1zd 775 30 post post JJ cord-015569-vy49r1zd 775 31 - - JJ cord-015569-vy49r1zd 775 32 resting resting JJ cord-015569-vy49r1zd 775 33 period period NN cord-015569-vy49r1zd 775 34 ( ( -LRB- cord-015569-vy49r1zd 775 35 25s 25 NNS cord-015569-vy49r1zd 775 36 ) ) -RRB- cord-015569-vy49r1zd 775 37 . . . cord-015569-vy49r1zd 776 1 We -PRON- PRP cord-015569-vy49r1zd 776 2 had have VBD cord-015569-vy49r1zd 776 3 24 24 CD cord-015569-vy49r1zd 776 4 trials trial NNS cord-015569-vy49r1zd 776 5 ( ( -LRB- cord-015569-vy49r1zd 776 6 3 3 CD cord-015569-vy49r1zd 776 7 odors odor NNS cord-015569-vy49r1zd 776 8 x x LS cord-015569-vy49r1zd 776 9 positive positive JJ cord-015569-vy49r1zd 776 10 / / SYM cord-015569-vy49r1zd 776 11 negative negative JJ cord-015569-vy49r1zd 777 1 information information NN cord-015569-vy49r1zd 777 2 x x SYM cord-015569-vy49r1zd 777 3 4 4 CD cord-015569-vy49r1zd 777 4 trials trial NNS cord-015569-vy49r1zd 777 5 ) ) -RRB- cord-015569-vy49r1zd 777 6 and and CC cord-015569-vy49r1zd 777 7 4 4 CD cord-015569-vy49r1zd 777 8 control control NN cord-015569-vy49r1zd 777 9 tasks task NNS cord-015569-vy49r1zd 777 10 with with IN cord-015569-vy49r1zd 777 11 odorless odorless NN cord-015569-vy49r1zd 777 12 . . . cord-015569-vy49r1zd 778 1 During during IN cord-015569-vy49r1zd 778 2 the the DT cord-015569-vy49r1zd 778 3 evaluation evaluation NN cord-015569-vy49r1zd 778 4 period period NN cord-015569-vy49r1zd 778 5 , , , cord-015569-vy49r1zd 778 6 subjects subject NNS cord-015569-vy49r1zd 778 7 evaluated evaluate VBD cord-015569-vy49r1zd 778 8 the the DT cord-015569-vy49r1zd 778 9 intensity intensity NN cord-015569-vy49r1zd 778 10 , , , cord-015569-vy49r1zd 778 11 pleasantness pleasantness NN cord-015569-vy49r1zd 778 12 / / SYM cord-015569-vy49r1zd 778 13 unpleasantness unpleasantness NN cord-015569-vy49r1zd 778 14 and and CC cord-015569-vy49r1zd 778 15 familiarity familiarity NN cord-015569-vy49r1zd 778 16 of of IN cord-015569-vy49r1zd 778 17 each each DT cord-015569-vy49r1zd 778 18 odor odor NN cord-015569-vy49r1zd 778 19 . . . cord-015569-vy49r1zd 779 1 The the DT cord-015569-vy49r1zd 779 2 stimuli stimulus NNS cord-015569-vy49r1zd 779 3 were be VBD cord-015569-vy49r1zd 779 4 presented present VBN cord-015569-vy49r1zd 779 5 by by IN cord-015569-vy49r1zd 779 6 random random JJ cord-015569-vy49r1zd 779 7 order order NN cord-015569-vy49r1zd 779 8 . . . cord-015569-vy49r1zd 780 1 As as IN cord-015569-vy49r1zd 780 2 a a DT cord-015569-vy49r1zd 780 3 result result NN cord-015569-vy49r1zd 780 4 , , , cord-015569-vy49r1zd 780 5 we -PRON- PRP cord-015569-vy49r1zd 780 6 showed show VBD cord-015569-vy49r1zd 780 7 the the DT cord-015569-vy49r1zd 780 8 different different JJ cord-015569-vy49r1zd 780 9 evaluation evaluation NN cord-015569-vy49r1zd 780 10 value value NN cord-015569-vy49r1zd 780 11 on on IN cord-015569-vy49r1zd 780 12 the the DT cord-015569-vy49r1zd 780 13 same same JJ cord-015569-vy49r1zd 780 14 odor odor NN cord-015569-vy49r1zd 780 15 but but CC cord-015569-vy49r1zd 780 16 different different JJ cord-015569-vy49r1zd 780 17 information information NN cord-015569-vy49r1zd 780 18 condition condition NN cord-015569-vy49r1zd 780 19 . . . cord-015569-vy49r1zd 781 1 The the DT cord-015569-vy49r1zd 781 2 positive positive JJ cord-015569-vy49r1zd 781 3 information information NN cord-015569-vy49r1zd 781 4 condition condition NN cord-015569-vy49r1zd 781 5 showed show VBD cord-015569-vy49r1zd 781 6 significantly significantly RB cord-015569-vy49r1zd 781 7 higher high JJR cord-015569-vy49r1zd 781 8 pleasant pleasant JJ cord-015569-vy49r1zd 781 9 value value NN cord-015569-vy49r1zd 781 10 than than IN cord-015569-vy49r1zd 781 11 negative negative JJ cord-015569-vy49r1zd 781 12 information information NN cord-015569-vy49r1zd 781 13 condition condition NN cord-015569-vy49r1zd 781 14 ( ( -LRB- cord-015569-vy49r1zd 781 15 p<.05 p<.05 NNP cord-015569-vy49r1zd 781 16 ) ) -RRB- cord-015569-vy49r1zd 781 17 . . . cord-015569-vy49r1zd 782 1 fNIRS fNIRS NNP cord-015569-vy49r1zd 782 2 data data NNP cord-015569-vy49r1zd 782 3 also also RB cord-015569-vy49r1zd 782 4 showed show VBD cord-015569-vy49r1zd 782 5 the the DT cord-015569-vy49r1zd 782 6 significantly significantly RB cord-015569-vy49r1zd 782 7 different different JJ cord-015569-vy49r1zd 782 8 prefrontal prefrontal JJ cord-015569-vy49r1zd 782 9 cortex cortex NN cord-015569-vy49r1zd 782 10 activation activation NN cord-015569-vy49r1zd 782 11 between between IN cord-015569-vy49r1zd 782 12 positive positive JJ cord-015569-vy49r1zd 782 13 and and CC cord-015569-vy49r1zd 782 14 negative negative JJ cord-015569-vy49r1zd 782 15 information information NN cord-015569-vy49r1zd 782 16 conditions condition NNS cord-015569-vy49r1zd 782 17 . . . cord-015569-vy49r1zd 783 1 We -PRON- PRP cord-015569-vy49r1zd 783 2 showed show VBD cord-015569-vy49r1zd 783 3 the the DT cord-015569-vy49r1zd 783 4 effects effect NNS cord-015569-vy49r1zd 783 5 of of IN cord-015569-vy49r1zd 783 6 positive positive JJ cord-015569-vy49r1zd 783 7 and and CC cord-015569-vy49r1zd 783 8 negative negative JJ cord-015569-vy49r1zd 783 9 information information NN cord-015569-vy49r1zd 783 10 on on IN cord-015569-vy49r1zd 783 11 a a DT cord-015569-vy49r1zd 783 12 same same JJ cord-015569-vy49r1zd 783 13 odor odor NN cord-015569-vy49r1zd 783 14 . . . cord-015569-vy49r1zd 784 1 First first JJ cord-015569-vy49r1zd 784 2 impression impression NN cord-015569-vy49r1zd 784 3 of of IN cord-015569-vy49r1zd 784 4 a a DT cord-015569-vy49r1zd 784 5 stranger stranger NN cord-015569-vy49r1zd 784 6 is be VBZ cord-015569-vy49r1zd 784 7 created create VBN cord-015569-vy49r1zd 784 8 by by IN cord-015569-vy49r1zd 784 9 several several JJ cord-015569-vy49r1zd 784 10 perceptions perception NNS cord-015569-vy49r1zd 784 11 , , , cord-015569-vy49r1zd 784 12 such such JJ cord-015569-vy49r1zd 784 13 as as IN cord-015569-vy49r1zd 784 14 face face NN cord-015569-vy49r1zd 784 15 , , , cord-015569-vy49r1zd 784 16 tone tone NN cord-015569-vy49r1zd 784 17 of of IN cord-015569-vy49r1zd 784 18 voice voice NN cord-015569-vy49r1zd 784 19 , , , cord-015569-vy49r1zd 784 20 speed speed NN cord-015569-vy49r1zd 784 21 of of IN cord-015569-vy49r1zd 784 22 words word NNS cord-015569-vy49r1zd 784 23 etc etc FW cord-015569-vy49r1zd 784 24 . . . cord-015569-vy49r1zd 785 1 There there EX cord-015569-vy49r1zd 785 2 are be VBP cord-015569-vy49r1zd 785 3 many many JJ cord-015569-vy49r1zd 785 4 researches research NNS cord-015569-vy49r1zd 785 5 on on IN cord-015569-vy49r1zd 785 6 development development NN cord-015569-vy49r1zd 785 7 of of IN cord-015569-vy49r1zd 785 8 first first JJ cord-015569-vy49r1zd 785 9 impressions impression NNS cord-015569-vy49r1zd 785 10 , , , cord-015569-vy49r1zd 785 11 but but CC cord-015569-vy49r1zd 785 12 there there EX cord-015569-vy49r1zd 785 13 are be VBP cord-015569-vy49r1zd 785 14 few few JJ cord-015569-vy49r1zd 785 15 researches research NNS cord-015569-vy49r1zd 785 16 that that WDT cord-015569-vy49r1zd 785 17 study study VBP cord-015569-vy49r1zd 785 18 a a DT cord-015569-vy49r1zd 785 19 role role NN cord-015569-vy49r1zd 785 20 of of IN cord-015569-vy49r1zd 785 21 olfaction olfaction NN cord-015569-vy49r1zd 785 22 on on IN cord-015569-vy49r1zd 785 23 development development NN cord-015569-vy49r1zd 785 24 of of IN cord-015569-vy49r1zd 785 25 first first JJ cord-015569-vy49r1zd 785 26 impressions impression NNS cord-015569-vy49r1zd 785 27 . . . cord-015569-vy49r1zd 786 1 We -PRON- PRP cord-015569-vy49r1zd 786 2 wear wear VBP cord-015569-vy49r1zd 786 3 perfume perfume NN cord-015569-vy49r1zd 786 4 not not RB cord-015569-vy49r1zd 786 5 only only RB cord-015569-vy49r1zd 786 6 because because IN cord-015569-vy49r1zd 786 7 we -PRON- PRP cord-015569-vy49r1zd 786 8 like like VBP cord-015569-vy49r1zd 786 9 it -PRON- PRP cord-015569-vy49r1zd 786 10 , , , cord-015569-vy49r1zd 786 11 but but CC cord-015569-vy49r1zd 786 12 also also RB cord-015569-vy49r1zd 786 13 because because IN cord-015569-vy49r1zd 786 14 we -PRON- PRP cord-015569-vy49r1zd 786 15 want want VBP cord-015569-vy49r1zd 786 16 someone someone NN cord-015569-vy49r1zd 786 17 to to TO cord-015569-vy49r1zd 786 18 have have VB cord-015569-vy49r1zd 786 19 good good JJ cord-015569-vy49r1zd 786 20 impressions impression NNS cord-015569-vy49r1zd 786 21 . . . cord-015569-vy49r1zd 787 1 This this DT cord-015569-vy49r1zd 787 2 study study NN cord-015569-vy49r1zd 787 3 aimed aim VBD cord-015569-vy49r1zd 787 4 to to TO cord-015569-vy49r1zd 787 5 investigate investigate VB cord-015569-vy49r1zd 787 6 whether whether IN cord-015569-vy49r1zd 787 7 the the DT cord-015569-vy49r1zd 787 8 perfume perfume NN cord-015569-vy49r1zd 787 9 that that WDT cord-015569-vy49r1zd 787 10 we -PRON- PRP cord-015569-vy49r1zd 787 11 wear wear VBP cord-015569-vy49r1zd 787 12 affects affect VBZ cord-015569-vy49r1zd 787 13 othersÕ othersõ VBP cord-015569-vy49r1zd 787 14 first first JJ cord-015569-vy49r1zd 787 15 impression impression NN cord-015569-vy49r1zd 787 16 for for IN cord-015569-vy49r1zd 787 17 us -PRON- PRP cord-015569-vy49r1zd 787 18 . . . cord-015569-vy49r1zd 788 1 Sixty sixty CD cord-015569-vy49r1zd 788 2 female female JJ cord-015569-vy49r1zd 788 3 university university NN cord-015569-vy49r1zd 788 4 students student NNS cord-015569-vy49r1zd 788 5 participated participate VBD cord-015569-vy49r1zd 788 6 in in IN cord-015569-vy49r1zd 788 7 this this DT cord-015569-vy49r1zd 788 8 study study NN cord-015569-vy49r1zd 788 9 , , , cord-015569-vy49r1zd 788 10 and and CC cord-015569-vy49r1zd 788 11 all all DT cord-015569-vy49r1zd 788 12 of of IN cord-015569-vy49r1zd 788 13 them -PRON- PRP cord-015569-vy49r1zd 788 14 were be VBD cord-015569-vy49r1zd 788 15 not not RB cord-015569-vy49r1zd 788 16 acquaintance acquaintance NN cord-015569-vy49r1zd 788 17 of of IN cord-015569-vy49r1zd 788 18 the the DT cord-015569-vy49r1zd 788 19 experimenters experimenter NNS cord-015569-vy49r1zd 788 20 . . . cord-015569-vy49r1zd 789 1 CK CK NNP cord-015569-vy49r1zd 789 2 One one CD cord-015569-vy49r1zd 789 3 , , , cord-015569-vy49r1zd 789 4 citrus citrus JJ cord-015569-vy49r1zd 789 5 - - HYPH cord-015569-vy49r1zd 789 6 floral floral JJ cord-015569-vy49r1zd 789 7 perfume perfume NN cord-015569-vy49r1zd 789 8 , , , cord-015569-vy49r1zd 789 9 and and CC cord-015569-vy49r1zd 789 10 COCO COCO NNP cord-015569-vy49r1zd 789 11 Chanel Chanel NNP cord-015569-vy49r1zd 789 12 , , , cord-015569-vy49r1zd 789 13 fresh fresh JJ cord-015569-vy49r1zd 789 14 oriental oriental JJ cord-015569-vy49r1zd 789 15 note note NN cord-015569-vy49r1zd 789 16 perfume perfume NN cord-015569-vy49r1zd 789 17 , , , cord-015569-vy49r1zd 789 18 were be VBD cord-015569-vy49r1zd 789 19 used use VBN cord-015569-vy49r1zd 789 20 as as IN cord-015569-vy49r1zd 789 21 olfactory olfactory JJ cord-015569-vy49r1zd 789 22 stimuli stimulus NNS cord-015569-vy49r1zd 789 23 . . . cord-015569-vy49r1zd 790 1 The the DT cord-015569-vy49r1zd 790 2 method method NN cord-015569-vy49r1zd 790 3 to to TO cord-015569-vy49r1zd 790 4 investigate investigate VB cord-015569-vy49r1zd 790 5 for for IN cord-015569-vy49r1zd 790 6 participantsÕ participantsÕ NNP cord-015569-vy49r1zd 790 7 impression impression NN cord-015569-vy49r1zd 790 8 for for IN cord-015569-vy49r1zd 790 9 the the DT cord-015569-vy49r1zd 790 10 female female JJ cord-015569-vy49r1zd 790 11 model model NN cord-015569-vy49r1zd 790 12 ( ( -LRB- cord-015569-vy49r1zd 790 13 experimenter experimenter NN cord-015569-vy49r1zd 790 14 ) ) -RRB- cord-015569-vy49r1zd 790 15 was be VBD cord-015569-vy49r1zd 790 16 TEG TEG NNP cord-015569-vy49r1zd 790 17 II II NNP cord-015569-vy49r1zd 791 1 ( ( -LRB- cord-015569-vy49r1zd 791 2 Tokyo Tokyo NNP cord-015569-vy49r1zd 791 3 University University NNP cord-015569-vy49r1zd 791 4 Egogram Egogram NNP cord-015569-vy49r1zd 791 5 ver ver NN cord-015569-vy49r1zd 791 6 . . . cord-015569-vy49r1zd 792 1 II II NNP cord-015569-vy49r1zd 792 2 , , , cord-015569-vy49r1zd 792 3 published publish VBN cord-015569-vy49r1zd 792 4 by by IN cord-015569-vy49r1zd 792 5 Kaneko Kaneko NNP cord-015569-vy49r1zd 792 6 Shobo Shobo NNP cord-015569-vy49r1zd 792 7 ) ) -RRB- cord-015569-vy49r1zd 792 8 . . . cord-015569-vy49r1zd 793 1 When when WRB cord-015569-vy49r1zd 793 2 the the DT cord-015569-vy49r1zd 793 3 model model NN cord-015569-vy49r1zd 793 4 wore wear VBD cord-015569-vy49r1zd 793 5 CK CK NNP cord-015569-vy49r1zd 793 6 One one CD cord-015569-vy49r1zd 793 7 , , , cord-015569-vy49r1zd 793 8 she -PRON- PRP cord-015569-vy49r1zd 793 9 was be VBD cord-015569-vy49r1zd 793 10 evaluated evaluate VBN cord-015569-vy49r1zd 793 11 as as IN cord-015569-vy49r1zd 793 12 having have VBG cord-015569-vy49r1zd 793 13 stronger strong JJR cord-015569-vy49r1zd 793 14 sense sense NN cord-015569-vy49r1zd 793 15 of of IN cord-015569-vy49r1zd 793 16 responsibility responsibility NN cord-015569-vy49r1zd 793 17 and and CC cord-015569-vy49r1zd 793 18 the the DT cord-015569-vy49r1zd 793 19 makings makings NN cord-015569-vy49r1zd 793 20 of of IN cord-015569-vy49r1zd 793 21 leader leader NN cord-015569-vy49r1zd 793 22 . . . cord-015569-vy49r1zd 794 1 On on IN cord-015569-vy49r1zd 794 2 the the DT cord-015569-vy49r1zd 794 3 other other JJ cord-015569-vy49r1zd 794 4 hand hand NN cord-015569-vy49r1zd 794 5 , , , cord-015569-vy49r1zd 794 6 when when WRB cord-015569-vy49r1zd 794 7 the the DT cord-015569-vy49r1zd 794 8 model model NN cord-015569-vy49r1zd 794 9 wore wear VBD cord-015569-vy49r1zd 794 10 COCO COCO NNP cord-015569-vy49r1zd 794 11 , , , cord-015569-vy49r1zd 794 12 she -PRON- PRP cord-015569-vy49r1zd 794 13 was be VBD cord-015569-vy49r1zd 794 14 evaluated evaluate VBN cord-015569-vy49r1zd 794 15 as as IN cord-015569-vy49r1zd 794 16 having have VBG cord-015569-vy49r1zd 794 17 unique unique JJ cord-015569-vy49r1zd 794 18 personality personality NN cord-015569-vy49r1zd 794 19 and and CC cord-015569-vy49r1zd 794 20 strong strong JJ cord-015569-vy49r1zd 794 21 self self NN cord-015569-vy49r1zd 794 22 - - HYPH cord-015569-vy49r1zd 794 23 assertion assertion NN cord-015569-vy49r1zd 794 24 . . . cord-015569-vy49r1zd 795 1 These these DT cord-015569-vy49r1zd 795 2 results result NNS cord-015569-vy49r1zd 795 3 show show VBP cord-015569-vy49r1zd 795 4 the the DT cord-015569-vy49r1zd 795 5 perfume perfume NN cord-015569-vy49r1zd 795 6 that that WDT cord-015569-vy49r1zd 795 7 we -PRON- PRP cord-015569-vy49r1zd 795 8 wear wear VBP cord-015569-vy49r1zd 795 9 changes change NNS cord-015569-vy49r1zd 795 10 othersÕ othersõ VBP cord-015569-vy49r1zd 795 11 first first JJ cord-015569-vy49r1zd 795 12 impressions impression NNS cord-015569-vy49r1zd 795 13 for for IN cord-015569-vy49r1zd 795 14 us -PRON- PRP cord-015569-vy49r1zd 795 15 . . . cord-015569-vy49r1zd 796 1 The the DT cord-015569-vy49r1zd 796 2 authors author NNS cord-015569-vy49r1zd 796 3 are be VBP cord-015569-vy49r1zd 796 4 continuing continue VBG cord-015569-vy49r1zd 796 5 to to TO cord-015569-vy49r1zd 796 6 study study VB cord-015569-vy49r1zd 796 7 about about IN cord-015569-vy49r1zd 796 8 this this DT cord-015569-vy49r1zd 796 9 phenomenon phenomenon NN cord-015569-vy49r1zd 796 10 , , , cord-015569-vy49r1zd 796 11 and and CC cord-015569-vy49r1zd 796 12 confirm confirm VB cord-015569-vy49r1zd 796 13 it -PRON- PRP cord-015569-vy49r1zd 796 14 with with IN cord-015569-vy49r1zd 796 15 another another DT cord-015569-vy49r1zd 796 16 models model NNS cord-015569-vy49r1zd 796 17 and and CC cord-015569-vy49r1zd 796 18 with with IN cord-015569-vy49r1zd 796 19 another another DT cord-015569-vy49r1zd 796 20 perfumes perfume NNS cord-015569-vy49r1zd 796 21 . . . cord-015569-vy49r1zd 797 1 # # $ cord-015569-vy49r1zd 797 2 72 72 CD cord-015569-vy49r1zd 797 3 A a DT cord-015569-vy49r1zd 797 4 study study NN cord-015569-vy49r1zd 797 5 of of IN cord-015569-vy49r1zd 797 6 the the DT cord-015569-vy49r1zd 797 7 image image NN cord-015569-vy49r1zd 797 8 congruency congruency NN cord-015569-vy49r1zd 797 9 between between IN cord-015569-vy49r1zd 797 10 bottle bottle NN cord-015569-vy49r1zd 797 11 appearance appearance NN cord-015569-vy49r1zd 797 12 and and CC cord-015569-vy49r1zd 797 13 fragrance fragrance NN cord-015569-vy49r1zd 797 14 of of IN cord-015569-vy49r1zd 797 15 perfume perfume NN cord-015569-vy49r1zd 797 16 Appearance appearance NN cord-015569-vy49r1zd 797 17 of of IN cord-015569-vy49r1zd 797 18 bottles bottle NNS cord-015569-vy49r1zd 797 19 might may MD cord-015569-vy49r1zd 797 20 influence influence VB cord-015569-vy49r1zd 797 21 on on IN cord-015569-vy49r1zd 797 22 the the DT cord-015569-vy49r1zd 797 23 evaluation evaluation NN cord-015569-vy49r1zd 797 24 of of IN cord-015569-vy49r1zd 797 25 perfumes perfume NNS cord-015569-vy49r1zd 797 26 as as IN cord-015569-vy49r1zd 797 27 visual visual JJ cord-015569-vy49r1zd 797 28 information information NN cord-015569-vy49r1zd 797 29 before before IN cord-015569-vy49r1zd 797 30 sniffing sniff VBG cord-015569-vy49r1zd 797 31 fragrance fragrance NN cord-015569-vy49r1zd 797 32 . . . cord-015569-vy49r1zd 798 1 We -PRON- PRP cord-015569-vy49r1zd 798 2 investigated investigate VBD cord-015569-vy49r1zd 798 3 such such JJ cord-015569-vy49r1zd 798 4 congruencies/ congruencies/ CD cord-015569-vy49r1zd 798 5 incongruencies incongruencie NNS cord-015569-vy49r1zd 798 6 between between IN cord-015569-vy49r1zd 798 7 visual visual JJ cord-015569-vy49r1zd 798 8 and and CC cord-015569-vy49r1zd 798 9 odor odor NN cord-015569-vy49r1zd 798 10 information information NN cord-015569-vy49r1zd 798 11 in in IN cord-015569-vy49r1zd 798 12 the the DT cord-015569-vy49r1zd 798 13 market market NN cord-015569-vy49r1zd 798 14 products product NNS cord-015569-vy49r1zd 798 15 of of IN cord-015569-vy49r1zd 798 16 perfume perfume NN cord-015569-vy49r1zd 798 17 through through IN cord-015569-vy49r1zd 798 18 the the DT cord-015569-vy49r1zd 798 19 two two CD cord-015569-vy49r1zd 798 20 experiments experiment NNS cord-015569-vy49r1zd 798 21 . . . cord-015569-vy49r1zd 799 1 In in IN cord-015569-vy49r1zd 799 2 the the DT cord-015569-vy49r1zd 799 3 experiment1 experiment1 NN cord-015569-vy49r1zd 799 4 , , , cord-015569-vy49r1zd 799 5 we -PRON- PRP cord-015569-vy49r1zd 799 6 investigated investigate VBD cord-015569-vy49r1zd 799 7 broad broad JJ cord-015569-vy49r1zd 799 8 constructs construct NNS cord-015569-vy49r1zd 799 9 of of IN cord-015569-vy49r1zd 799 10 image image NN cord-015569-vy49r1zd 799 11 aroused arouse VBN cord-015569-vy49r1zd 799 12 from from IN cord-015569-vy49r1zd 799 13 appearance appearance NN cord-015569-vy49r1zd 799 14 of of IN cord-015569-vy49r1zd 799 15 bottles bottle NNS cord-015569-vy49r1zd 799 16 and and CC cord-015569-vy49r1zd 799 17 flagrance flagrance NN cord-015569-vy49r1zd 799 18 of of IN cord-015569-vy49r1zd 799 19 perfumes perfume NNS cord-015569-vy49r1zd 799 20 , , , cord-015569-vy49r1zd 799 21 and and CC cord-015569-vy49r1zd 799 22 reviewed review VBD cord-015569-vy49r1zd 799 23 congruencies congruencie NNS cord-015569-vy49r1zd 799 24 between between IN cord-015569-vy49r1zd 799 25 bottles bottle NNS cord-015569-vy49r1zd 799 26 and and CC cord-015569-vy49r1zd 799 27 fragrances fragrance NNS cord-015569-vy49r1zd 799 28 . . . cord-015569-vy49r1zd 800 1 We -PRON- PRP cord-015569-vy49r1zd 800 2 selected select VBD cord-015569-vy49r1zd 800 3 10 10 CD cord-015569-vy49r1zd 800 4 products product NNS cord-015569-vy49r1zd 800 5 as as IN cord-015569-vy49r1zd 800 6 samples sample NNS cord-015569-vy49r1zd 800 7 , , , cord-015569-vy49r1zd 800 8 and and CC cord-015569-vy49r1zd 800 9 used use VBD cord-015569-vy49r1zd 800 10 ' ' '' cord-015569-vy49r1zd 800 11 ' ' `` cord-015569-vy49r1zd 800 12 Napping Napping NNP cord-015569-vy49r1zd 800 13 ' ' '' cord-015569-vy49r1zd 800 14 ' ' '' cord-015569-vy49r1zd 800 15 for for IN cord-015569-vy49r1zd 800 16 experiment1 experiment1 NN cord-015569-vy49r1zd 800 17 . . . cord-015569-vy49r1zd 801 1 In in IN cord-015569-vy49r1zd 801 2 Napping Napping NNP cord-015569-vy49r1zd 801 3 , , , cord-015569-vy49r1zd 801 4 subject subject JJ cord-015569-vy49r1zd 801 5 sort sort RB cord-015569-vy49r1zd 801 6 the the DT cord-015569-vy49r1zd 801 7 samples sample NNS cord-015569-vy49r1zd 801 8 on on IN cord-015569-vy49r1zd 801 9 the the DT cord-015569-vy49r1zd 801 10 space space NN cord-015569-vy49r1zd 801 11 reflecting reflect VBG cord-015569-vy49r1zd 801 12 sensory sensory JJ cord-015569-vy49r1zd 801 13 similarities similarity NNS cord-015569-vy49r1zd 801 14 . . . cord-015569-vy49r1zd 802 1 11 11 CD cord-015569-vy49r1zd 803 1 our -PRON- PRP$ cord-015569-vy49r1zd 803 2 subjects subject NNS cord-015569-vy49r1zd 803 3 carried carry VBD cord-015569-vy49r1zd 803 4 out out RP cord-015569-vy49r1zd 803 5 Napping Napping NNP cord-015569-vy49r1zd 803 6 under under IN cord-015569-vy49r1zd 803 7 the the DT cord-015569-vy49r1zd 803 8 two two CD cord-015569-vy49r1zd 803 9 conditions condition NNS cord-015569-vy49r1zd 803 10 . . . cord-015569-vy49r1zd 804 1 Subjects subject NNS cord-015569-vy49r1zd 804 2 were be VBD cord-015569-vy49r1zd 804 3 asked ask VBN cord-015569-vy49r1zd 804 4 to to TO cord-015569-vy49r1zd 804 5 sort sort VB cord-015569-vy49r1zd 804 6 samples sample NNS cord-015569-vy49r1zd 804 7 according accord VBG cord-015569-vy49r1zd 804 8 to to IN cord-015569-vy49r1zd 804 9 similarities similarity NNS cord-015569-vy49r1zd 804 10 of of IN cord-015569-vy49r1zd 804 11 scents scent NNS cord-015569-vy49r1zd 804 12 . . . cord-015569-vy49r1zd 805 1 These these DT cord-015569-vy49r1zd 805 2 scents scent NNS cord-015569-vy49r1zd 805 3 were be VBD cord-015569-vy49r1zd 805 4 sniffed sniff VBN cord-015569-vy49r1zd 805 5 actually actually RB cord-015569-vy49r1zd 805 6 in in IN cord-015569-vy49r1zd 805 7 the the DT cord-015569-vy49r1zd 805 8 sniffing sniffing NN cord-015569-vy49r1zd 805 9 condition condition NN cord-015569-vy49r1zd 805 10 , , , cord-015569-vy49r1zd 805 11 but but CC cord-015569-vy49r1zd 805 12 in in IN cord-015569-vy49r1zd 805 13 the the DT cord-015569-vy49r1zd 805 14 viewing view VBG cord-015569-vy49r1zd 805 15 condition condition NN cord-015569-vy49r1zd 805 16 , , , cord-015569-vy49r1zd 805 17 scents scent NNS cord-015569-vy49r1zd 805 18 were be VBD cord-015569-vy49r1zd 805 19 imagined imagine VBN cord-015569-vy49r1zd 805 20 from from IN cord-015569-vy49r1zd 805 21 appearance appearance NN cord-015569-vy49r1zd 805 22 of of IN cord-015569-vy49r1zd 805 23 bottles bottle NNS cord-015569-vy49r1zd 805 24 . . . cord-015569-vy49r1zd 806 1 Distances distance NNS cord-015569-vy49r1zd 806 2 matrixes matrix NNS cord-015569-vy49r1zd 806 3 between between IN cord-015569-vy49r1zd 806 4 samples sample NNS cord-015569-vy49r1zd 806 5 were be VBD cord-015569-vy49r1zd 806 6 measured measure VBN cord-015569-vy49r1zd 806 7 from from IN cord-015569-vy49r1zd 806 8 results result NNS cord-015569-vy49r1zd 806 9 of of IN cord-015569-vy49r1zd 806 10 Napping Napping NNP cord-015569-vy49r1zd 806 11 , , , cord-015569-vy49r1zd 806 12 and and CC cord-015569-vy49r1zd 806 13 were be VBD cord-015569-vy49r1zd 806 14 used use VBN cord-015569-vy49r1zd 806 15 for for IN cord-015569-vy49r1zd 806 16 Multi Multi NNP cord-015569-vy49r1zd 806 17 - - JJ cord-015569-vy49r1zd 806 18 Dimensional dimensional JJ cord-015569-vy49r1zd 806 19 Scaling Scaling NNP cord-015569-vy49r1zd 806 20 ( ( -LRB- cord-015569-vy49r1zd 806 21 MDS MDS NNP cord-015569-vy49r1zd 806 22 ) ) -RRB- cord-015569-vy49r1zd 806 23 . . . cord-015569-vy49r1zd 807 1 The the DT cord-015569-vy49r1zd 807 2 result result NN cord-015569-vy49r1zd 807 3 of of IN cord-015569-vy49r1zd 807 4 MDS MDS NNP cord-015569-vy49r1zd 807 5 showed show VBD cord-015569-vy49r1zd 807 6 that that IN cord-015569-vy49r1zd 807 7 dimension1 dimension1 NNP cord-015569-vy49r1zd 807 8 could could MD cord-015569-vy49r1zd 807 9 represent represent VB cord-015569-vy49r1zd 807 10 major major JJ cord-015569-vy49r1zd 807 11 image image NN cord-015569-vy49r1zd 807 12 of of IN cord-015569-vy49r1zd 807 13 perfumes perfume NNS cord-015569-vy49r1zd 807 14 ( ( -LRB- cord-015569-vy49r1zd 807 15 for for IN cord-015569-vy49r1zd 807 16 men man NNS cord-015569-vy49r1zd 807 17 or or CC cord-015569-vy49r1zd 807 18 female female NN cord-015569-vy49r1zd 807 19 ) ) -RRB- cord-015569-vy49r1zd 807 20 in in IN cord-015569-vy49r1zd 807 21 the the DT cord-015569-vy49r1zd 807 22 both both DT cord-015569-vy49r1zd 807 23 conditions condition NNS cord-015569-vy49r1zd 807 24 , , , cord-015569-vy49r1zd 807 25 and and CC cord-015569-vy49r1zd 807 26 that that IN cord-015569-vy49r1zd 807 27 diman diman NN cord-015569-vy49r1zd 807 28 - - HYPH cord-015569-vy49r1zd 807 29 sion2 sion2 NN cord-015569-vy49r1zd 807 30 in in IN cord-015569-vy49r1zd 807 31 the the DT cord-015569-vy49r1zd 807 32 viewing view VBG cord-015569-vy49r1zd 807 33 condition condition NN cord-015569-vy49r1zd 807 34 could could MD cord-015569-vy49r1zd 807 35 represent represent VB cord-015569-vy49r1zd 807 36 lightness lightness NN cord-015569-vy49r1zd 807 37 of of IN cord-015569-vy49r1zd 807 38 scents scent NNS cord-015569-vy49r1zd 807 39 related relate VBN cord-015569-vy49r1zd 807 40 to to IN cord-015569-vy49r1zd 807 41 transparencies transparency NNS cord-015569-vy49r1zd 807 42 of of IN cord-015569-vy49r1zd 807 43 bottles bottle NNS cord-015569-vy49r1zd 807 44 . . . cord-015569-vy49r1zd 808 1 However however RB cord-015569-vy49r1zd 808 2 , , , cord-015569-vy49r1zd 808 3 we -PRON- PRP cord-015569-vy49r1zd 808 4 could could MD cord-015569-vy49r1zd 808 5 not not RB cord-015569-vy49r1zd 808 6 find find VB cord-015569-vy49r1zd 808 7 systematic systematic JJ cord-015569-vy49r1zd 808 8 feature feature NN cord-015569-vy49r1zd 808 9 change change NN cord-015569-vy49r1zd 808 10 of of IN cord-015569-vy49r1zd 808 11 scents scent NNS cord-015569-vy49r1zd 808 12 on on IN cord-015569-vy49r1zd 808 13 dimension2 dimension2 NN cord-015569-vy49r1zd 808 14 in in IN cord-015569-vy49r1zd 808 15 sniffing sniff VBG cord-015569-vy49r1zd 808 16 condition condition NN cord-015569-vy49r1zd 808 17 . . . cord-015569-vy49r1zd 809 1 It -PRON- PRP cord-015569-vy49r1zd 809 2 may may MD cord-015569-vy49r1zd 809 3 suggest suggest VB cord-015569-vy49r1zd 809 4 complexity complexity NN cord-015569-vy49r1zd 809 5 of of IN cord-015569-vy49r1zd 809 6 scents scent NNS cord-015569-vy49r1zd 809 7 sniffed sniff VBD cord-015569-vy49r1zd 809 8 actually actually RB cord-015569-vy49r1zd 809 9 . . . cord-015569-vy49r1zd 810 1 We -PRON- PRP cord-015569-vy49r1zd 810 2 then then RB cord-015569-vy49r1zd 810 3 examined examine VBD cord-015569-vy49r1zd 810 4 the the DT cord-015569-vy49r1zd 810 5 qualitative qualitative JJ cord-015569-vy49r1zd 810 6 aspects aspect NNS cord-015569-vy49r1zd 810 7 in in IN cord-015569-vy49r1zd 810 8 congruencies/ congruencies/ CD cord-015569-vy49r1zd 810 9 incongruencies incongruencie NNS cord-015569-vy49r1zd 810 10 between between IN cord-015569-vy49r1zd 810 11 bottles bottle NNS cord-015569-vy49r1zd 810 12 and and CC cord-015569-vy49r1zd 810 13 flagrancies flagrancie NNS cord-015569-vy49r1zd 810 14 in in IN cord-015569-vy49r1zd 810 15 the the DT cord-015569-vy49r1zd 810 16 experiment2 experiment2 NN cord-015569-vy49r1zd 810 17 . . . cord-015569-vy49r1zd 811 1 We -PRON- PRP cord-015569-vy49r1zd 811 2 selected select VBD cord-015569-vy49r1zd 811 3 5 5 CD cord-015569-vy49r1zd 811 4 among among IN cord-015569-vy49r1zd 811 5 10 10 CD cord-015569-vy49r1zd 811 6 perfumes perfume NNS cord-015569-vy49r1zd 811 7 used use VBN cord-015569-vy49r1zd 811 8 in in IN cord-015569-vy49r1zd 811 9 experiment1 experiment1 NN cord-015569-vy49r1zd 811 10 , , , cord-015569-vy49r1zd 811 11 and and CC cord-015569-vy49r1zd 811 12 used use VBD cord-015569-vy49r1zd 811 13 10 10 CD cord-015569-vy49r1zd 811 14 descriptive descriptive JJ cord-015569-vy49r1zd 811 15 terms term NNS cord-015569-vy49r1zd 811 16 to to TO cord-015569-vy49r1zd 811 17 evaluate evaluate VB cord-015569-vy49r1zd 811 18 each each DT cord-015569-vy49r1zd 811 19 of of IN cord-015569-vy49r1zd 811 20 the the DT cord-015569-vy49r1zd 811 21 samples sample NNS cord-015569-vy49r1zd 811 22 . . . cord-015569-vy49r1zd 812 1 In in IN cord-015569-vy49r1zd 812 2 the the DT cord-015569-vy49r1zd 812 3 results result NNS cord-015569-vy49r1zd 812 4 of of IN cord-015569-vy49r1zd 812 5 experiment experiment NN cord-015569-vy49r1zd 812 6 2 2 CD cord-015569-vy49r1zd 812 7 , , , cord-015569-vy49r1zd 812 8 we -PRON- PRP cord-015569-vy49r1zd 812 9 could could MD cord-015569-vy49r1zd 812 10 not not RB cord-015569-vy49r1zd 812 11 find find VB cord-015569-vy49r1zd 812 12 any any DT cord-015569-vy49r1zd 812 13 relations relation NNS cord-015569-vy49r1zd 812 14 between between IN cord-015569-vy49r1zd 812 15 terms term NNS cord-015569-vy49r1zd 812 16 with with IN cord-015569-vy49r1zd 812 17 perfumes perfume NNS cord-015569-vy49r1zd 812 18 . . . cord-015569-vy49r1zd 813 1 Changes change NNS cord-015569-vy49r1zd 813 2 of of IN cord-015569-vy49r1zd 813 3 the the DT cord-015569-vy49r1zd 813 4 physiological physiological JJ cord-015569-vy49r1zd 813 5 parameters parameter NNS cord-015569-vy49r1zd 813 6 ( ( -LRB- cord-015569-vy49r1zd 813 7 saliva saliva NN cord-015569-vy49r1zd 813 8 amylase amylase NN cord-015569-vy49r1zd 813 9 , , , cord-015569-vy49r1zd 813 10 heart heart NN cord-015569-vy49r1zd 813 11 rate rate NN cord-015569-vy49r1zd 813 12 , , , cord-015569-vy49r1zd 813 13 and and CC cord-015569-vy49r1zd 813 14 brain brain NN cord-015569-vy49r1zd 813 15 waves wave NNS cord-015569-vy49r1zd 813 16 ) ) -RRB- cord-015569-vy49r1zd 813 17 of of IN cord-015569-vy49r1zd 813 18 10 10 CD cord-015569-vy49r1zd 813 19 subjects subject NNS cord-015569-vy49r1zd 813 20 during during IN cord-015569-vy49r1zd 813 21 the the DT cord-015569-vy49r1zd 813 22 smelling smelling NN cord-015569-vy49r1zd 813 23 of of IN cord-015569-vy49r1zd 813 24 the the DT cord-015569-vy49r1zd 813 25 bark bark NN cord-015569-vy49r1zd 813 26 oil oil NN cord-015569-vy49r1zd 813 27 of of IN cord-015569-vy49r1zd 813 28 Lindera Lindera NNP cord-015569-vy49r1zd 813 29 umbellata umbellata NNS cord-015569-vy49r1zd 813 30 were be VBD cord-015569-vy49r1zd 813 31 measured measure VBN cord-015569-vy49r1zd 813 32 . . . cord-015569-vy49r1zd 814 1 The the DT cord-015569-vy49r1zd 814 2 value value NN cord-015569-vy49r1zd 814 3 of of IN cord-015569-vy49r1zd 814 4 saliva saliva NN cord-015569-vy49r1zd 814 5 amylase amylase NN cord-015569-vy49r1zd 814 6 did do VBD cord-015569-vy49r1zd 814 7 not not RB cord-015569-vy49r1zd 814 8 change change VB cord-015569-vy49r1zd 814 9 during during IN cord-015569-vy49r1zd 814 10 the the DT cord-015569-vy49r1zd 814 11 smelling smelling NN cord-015569-vy49r1zd 814 12 of of IN cord-015569-vy49r1zd 814 13 the the DT cord-015569-vy49r1zd 814 14 bark bark NN cord-015569-vy49r1zd 814 15 oil oil NN cord-015569-vy49r1zd 814 16 . . . cord-015569-vy49r1zd 815 1 The the DT cord-015569-vy49r1zd 815 2 proportion proportion NN cord-015569-vy49r1zd 815 3 of of IN cord-015569-vy49r1zd 815 4 the the DT cord-015569-vy49r1zd 815 5 parasympathetic parasympathetic JJ cord-015569-vy49r1zd 815 6 nervous nervous JJ cord-015569-vy49r1zd 815 7 system system NN cord-015569-vy49r1zd 815 8 increased increase VBD cord-015569-vy49r1zd 815 9 significantly significantly RB cord-015569-vy49r1zd 815 10 during during IN cord-015569-vy49r1zd 815 11 the the DT cord-015569-vy49r1zd 815 12 smelling smelling NN cord-015569-vy49r1zd 815 13 of of IN cord-015569-vy49r1zd 815 14 the the DT cord-015569-vy49r1zd 815 15 oil oil NN cord-015569-vy49r1zd 815 16 , , , cord-015569-vy49r1zd 815 17 while while IN cord-015569-vy49r1zd 815 18 that that DT cord-015569-vy49r1zd 815 19 of of IN cord-015569-vy49r1zd 815 20 the the DT cord-015569-vy49r1zd 815 21 sympathetic sympathetic JJ cord-015569-vy49r1zd 815 22 nervous nervous JJ cord-015569-vy49r1zd 815 23 system system NN cord-015569-vy49r1zd 815 24 decreased decrease VBD cord-015569-vy49r1zd 815 25 . . . cord-015569-vy49r1zd 816 1 On on IN cord-015569-vy49r1zd 816 2 the the DT cord-015569-vy49r1zd 816 3 other other JJ cord-015569-vy49r1zd 816 4 hand hand NN cord-015569-vy49r1zd 816 5 , , , cord-015569-vy49r1zd 816 6 the the DT cord-015569-vy49r1zd 816 7 proportion proportion NN cord-015569-vy49r1zd 816 8 of of IN cord-015569-vy49r1zd 816 9 b b NN cord-015569-vy49r1zd 816 10 - - HYPH cord-015569-vy49r1zd 816 11 wave wave NN cord-015569-vy49r1zd 816 12 decreased decrease VBD cord-015569-vy49r1zd 816 13 significantly significantly RB cord-015569-vy49r1zd 816 14 during during IN cord-015569-vy49r1zd 816 15 the the DT cord-015569-vy49r1zd 816 16 smelling smelling NN cord-015569-vy49r1zd 816 17 of of IN cord-015569-vy49r1zd 816 18 the the DT cord-015569-vy49r1zd 816 19 oil oil NN cord-015569-vy49r1zd 816 20 . . . cord-015569-vy49r1zd 817 1 Thus thus RB cord-015569-vy49r1zd 817 2 , , , cord-015569-vy49r1zd 817 3 the the DT cord-015569-vy49r1zd 817 4 bark bark NN cord-015569-vy49r1zd 817 5 oil oil NN cord-015569-vy49r1zd 817 6 exhibited exhibit VBD cord-015569-vy49r1zd 817 7 the the DT cord-015569-vy49r1zd 817 8 relaxation relaxation NN cord-015569-vy49r1zd 817 9 effects effect NNS cord-015569-vy49r1zd 817 10 for for IN cord-015569-vy49r1zd 817 11 the the DT cord-015569-vy49r1zd 817 12 subjects subject NNS cord-015569-vy49r1zd 817 13 . . . cord-015569-vy49r1zd 818 1 The the DT cord-015569-vy49r1zd 818 2 bark bark NN cord-015569-vy49r1zd 818 3 oils oil NNS cord-015569-vy49r1zd 818 4 included include VBD cord-015569-vy49r1zd 818 5 monoterpene monoterpene NNP cord-015569-vy49r1zd 818 6 alcohols alcohol NNS cord-015569-vy49r1zd 818 7 ( ( -LRB- cord-015569-vy49r1zd 818 8 73.19 73.19 CD cord-015569-vy49r1zd 818 9 % % NN cord-015569-vy49r1zd 818 10 ) ) -RRB- cord-015569-vy49r1zd 818 11 and and CC cord-015569-vy49r1zd 818 12 ketones ketone NNS cord-015569-vy49r1zd 818 13 ( ( -LRB- cord-015569-vy49r1zd 818 14 6.99 6.99 CD cord-015569-vy49r1zd 818 15 % % NN cord-015569-vy49r1zd 818 16 ) ) -RRB- cord-015569-vy49r1zd 818 17 , , , cord-015569-vy49r1zd 818 18 monoterpene monoterpene NNP cord-015569-vy49r1zd 818 19 oxides oxide NNS cord-015569-vy49r1zd 818 20 ( ( -LRB- cord-015569-vy49r1zd 818 21 5.59 5.59 CD cord-015569-vy49r1zd 818 22 % % NN cord-015569-vy49r1zd 818 23 ) ) -RRB- cord-015569-vy49r1zd 818 24 , , , cord-015569-vy49r1zd 818 25 monoterpene monoterpene NNP cord-015569-vy49r1zd 818 26 hydrocarbons hydrocarbon NNS cord-015569-vy49r1zd 818 27 ( ( -LRB- cord-015569-vy49r1zd 818 28 5.18 5.18 CD cord-015569-vy49r1zd 818 29 % % NN cord-015569-vy49r1zd 818 30 ) ) -RRB- cord-015569-vy49r1zd 818 31 , , , cord-015569-vy49r1zd 818 32 and and CC cord-015569-vy49r1zd 818 33 others other NNS cord-015569-vy49r1zd 818 34 . . . cord-015569-vy49r1zd 819 1 Among among IN cord-015569-vy49r1zd 819 2 of of IN cord-015569-vy49r1zd 819 3 these these DT cord-015569-vy49r1zd 819 4 , , , cord-015569-vy49r1zd 819 5 linalool linalool NN cord-015569-vy49r1zd 819 6 ( ( -LRB- cord-015569-vy49r1zd 819 7 63.70 63.70 CD cord-015569-vy49r1zd 819 8 % % NN cord-015569-vy49r1zd 819 9 ) ) -RRB- cord-015569-vy49r1zd 819 10 was be VBD cord-015569-vy49r1zd 819 11 the the DT cord-015569-vy49r1zd 819 12 most most RBS cord-015569-vy49r1zd 819 13 abundant abundant JJ cord-015569-vy49r1zd 819 14 component component NN cord-015569-vy49r1zd 819 15 . . . cord-015569-vy49r1zd 820 1 Here here RB cord-015569-vy49r1zd 820 2 we -PRON- PRP cord-015569-vy49r1zd 820 3 investigated investigate VBD cord-015569-vy49r1zd 820 4 relationship relationship NN cord-015569-vy49r1zd 820 5 between between IN cord-015569-vy49r1zd 820 6 the the DT cord-015569-vy49r1zd 820 7 number number NN cord-015569-vy49r1zd 820 8 of of IN cord-015569-vy49r1zd 820 9 constituent constituent NN cord-015569-vy49r1zd 820 10 odors odor NNS cord-015569-vy49r1zd 820 11 and and CC cord-015569-vy49r1zd 820 12 odor odor NN cord-015569-vy49r1zd 820 13 pleasantness pleasantness NN cord-015569-vy49r1zd 820 14 . . . cord-015569-vy49r1zd 821 1 We -PRON- PRP cord-015569-vy49r1zd 821 2 hypothesized hypothesize VBD cord-015569-vy49r1zd 821 3 that that IN cord-015569-vy49r1zd 821 4 the the DT cord-015569-vy49r1zd 821 5 stability stability NN cord-015569-vy49r1zd 821 6 of of IN cord-015569-vy49r1zd 821 7 the the DT cord-015569-vy49r1zd 821 8 olfactory olfactory JJ cord-015569-vy49r1zd 821 9 perception perception NN cord-015569-vy49r1zd 821 10 depends depend VBZ cord-015569-vy49r1zd 821 11 on on IN cord-015569-vy49r1zd 821 12 the the DT cord-015569-vy49r1zd 821 13 number number NN cord-015569-vy49r1zd 821 14 of of IN cord-015569-vy49r1zd 821 15 odor odor NN cord-015569-vy49r1zd 821 16 components component NNS cord-015569-vy49r1zd 821 17 and and CC cord-015569-vy49r1zd 821 18 their -PRON- PRP$ cord-015569-vy49r1zd 821 19 molecular molecular JJ cord-015569-vy49r1zd 821 20 variability variability NN cord-015569-vy49r1zd 821 21 . . . cord-015569-vy49r1zd 822 1 We -PRON- PRP cord-015569-vy49r1zd 822 2 especially especially RB cord-015569-vy49r1zd 822 3 focused focus VBD cord-015569-vy49r1zd 822 4 on on IN cord-015569-vy49r1zd 822 5 odor odor NN cord-015569-vy49r1zd 822 6 pleasantness pleasantness NN cord-015569-vy49r1zd 822 7 , , , cord-015569-vy49r1zd 822 8 which which WDT cord-015569-vy49r1zd 822 9 best good JJS cord-015569-vy49r1zd 822 10 explains explain VBZ cord-015569-vy49r1zd 822 11 molecular molecular JJ cord-015569-vy49r1zd 822 12 variability variability NN cord-015569-vy49r1zd 822 13 of of IN cord-015569-vy49r1zd 822 14 odorants odorant NNS cord-015569-vy49r1zd 822 15 in in IN cord-015569-vy49r1zd 822 16 the the DT cord-015569-vy49r1zd 822 17 natural natural JJ cord-015569-vy49r1zd 822 18 world world NN cord-015569-vy49r1zd 822 19 . . . cord-015569-vy49r1zd 823 1 Three three CD cord-015569-vy49r1zd 823 2 different different JJ cord-015569-vy49r1zd 823 3 categories category NNS cord-015569-vy49r1zd 823 4 of of IN cord-015569-vy49r1zd 823 5 odors odor NNS cord-015569-vy49r1zd 823 6 , , , cord-015569-vy49r1zd 823 7 aliphatics aliphatic NNS cord-015569-vy49r1zd 823 8 , , , cord-015569-vy49r1zd 823 9 aromatics aromatic NNS cord-015569-vy49r1zd 823 10 and and CC cord-015569-vy49r1zd 823 11 terpenoids terpenoid NNS cord-015569-vy49r1zd 823 12 , , , cord-015569-vy49r1zd 823 13 were be VBD cord-015569-vy49r1zd 823 14 used use VBN cord-015569-vy49r1zd 823 15 in in IN cord-015569-vy49r1zd 823 16 this this DT cord-015569-vy49r1zd 823 17 study study NN cord-015569-vy49r1zd 823 18 . . . cord-015569-vy49r1zd 824 1 We -PRON- PRP cord-015569-vy49r1zd 824 2 used use VBD cord-015569-vy49r1zd 824 3 5 5 CD cord-015569-vy49r1zd 824 4 or or CC cord-015569-vy49r1zd 824 5 10 10 CD cord-015569-vy49r1zd 824 6 odors odor NNS cord-015569-vy49r1zd 824 7 for for IN cord-015569-vy49r1zd 824 8 preparing prepare VBG cord-015569-vy49r1zd 824 9 multi multi JJ cord-015569-vy49r1zd 824 10 component component NN cord-015569-vy49r1zd 824 11 odors odor NNS cord-015569-vy49r1zd 824 12 . . . cord-015569-vy49r1zd 825 1 Odor odor NN cord-015569-vy49r1zd 825 2 pleasantness pleasantness NN cord-015569-vy49r1zd 825 3 for for IN cord-015569-vy49r1zd 825 4 the the DT cord-015569-vy49r1zd 825 5 multi multi JJ cord-015569-vy49r1zd 825 6 component component NN cord-015569-vy49r1zd 825 7 odors odor NNS cord-015569-vy49r1zd 825 8 tended tend VBD cord-015569-vy49r1zd 825 9 to to TO cord-015569-vy49r1zd 825 10 be be VB cord-015569-vy49r1zd 825 11 more more RBR cord-015569-vy49r1zd 825 12 stable stable JJ cord-015569-vy49r1zd 825 13 against against IN cord-015569-vy49r1zd 825 14 concentration concentration NN cord-015569-vy49r1zd 825 15 changes change NNS cord-015569-vy49r1zd 825 16 than than IN cord-015569-vy49r1zd 825 17 that that DT cord-015569-vy49r1zd 825 18 of of IN cord-015569-vy49r1zd 825 19 the the DT cord-015569-vy49r1zd 825 20 single single JJ cord-015569-vy49r1zd 825 21 component component NN cord-015569-vy49r1zd 825 22 odors odor NNS cord-015569-vy49r1zd 825 23 . . . cord-015569-vy49r1zd 826 1 Notably notably RB cord-015569-vy49r1zd 826 2 , , , cord-015569-vy49r1zd 826 3 multi multi JJ cord-015569-vy49r1zd 826 4 component component NN cord-015569-vy49r1zd 826 5 odors odor NNS cord-015569-vy49r1zd 826 6 containing contain VBG cord-015569-vy49r1zd 826 7 odorants odorant NNS cord-015569-vy49r1zd 826 8 of of IN cord-015569-vy49r1zd 826 9 all all DT cord-015569-vy49r1zd 826 10 categories category NNS cord-015569-vy49r1zd 826 11 showed show VBD cord-015569-vy49r1zd 826 12 higher high JJR cord-015569-vy49r1zd 826 13 stability stability NN cord-015569-vy49r1zd 826 14 than than IN cord-015569-vy49r1zd 826 15 odors odor NNS cord-015569-vy49r1zd 826 16 containing contain VBG cord-015569-vy49r1zd 826 17 single single JJ cord-015569-vy49r1zd 826 18 odor odor NN cord-015569-vy49r1zd 826 19 category category NN cord-015569-vy49r1zd 826 20 . . . cord-015569-vy49r1zd 827 1 Future future JJ cord-015569-vy49r1zd 827 2 study study NN cord-015569-vy49r1zd 827 3 for for IN cord-015569-vy49r1zd 827 4 large large JJ cord-015569-vy49r1zd 827 5 number number NN cord-015569-vy49r1zd 827 6 of of IN cord-015569-vy49r1zd 827 7 components component NNS cord-015569-vy49r1zd 827 8 with with IN cord-015569-vy49r1zd 827 9 different different JJ cord-015569-vy49r1zd 827 10 molecular molecular JJ cord-015569-vy49r1zd 827 11 variability variability NN cord-015569-vy49r1zd 827 12 will will MD cord-015569-vy49r1zd 827 13 reveal reveal VB cord-015569-vy49r1zd 827 14 rules rule NNS cord-015569-vy49r1zd 827 15 for for IN cord-015569-vy49r1zd 827 16 the the DT cord-015569-vy49r1zd 827 17 prediction prediction NN cord-015569-vy49r1zd 827 18 of of IN cord-015569-vy49r1zd 827 19 the the DT cord-015569-vy49r1zd 827 20 odor odor NN cord-015569-vy49r1zd 827 21 perception perception NN cord-015569-vy49r1zd 827 22 for for IN cord-015569-vy49r1zd 827 23 odor odor NN cord-015569-vy49r1zd 827 24 mixtures mixture NNS cord-015569-vy49r1zd 827 25 . . . cord-015569-vy49r1zd 828 1 # # $ cord-015569-vy49r1zd 828 2 75 75 CD cord-015569-vy49r1zd 828 3 fMRI fmri NN cord-015569-vy49r1zd 828 4 of of IN cord-015569-vy49r1zd 828 5 brain brain NN cord-015569-vy49r1zd 828 6 responses response NNS cord-015569-vy49r1zd 828 7 to to IN cord-015569-vy49r1zd 828 8 complex complex JJ cord-015569-vy49r1zd 828 9 odor odor NN cord-015569-vy49r1zd 828 10 and and CC cord-015569-vy49r1zd 828 11 visual visual JJ cord-015569-vy49r1zd 828 12 stimuli stimulus NNS cord-015569-vy49r1zd 829 1 One one CD cord-015569-vy49r1zd 829 2 of of IN cord-015569-vy49r1zd 829 3 the the DT cord-015569-vy49r1zd 829 4 most most RBS cord-015569-vy49r1zd 829 5 important important JJ cord-015569-vy49r1zd 829 6 features feature NNS cord-015569-vy49r1zd 829 7 of of IN cord-015569-vy49r1zd 829 8 odor odor NN cord-015569-vy49r1zd 829 9 perception perception NN cord-015569-vy49r1zd 829 10 is be VBZ cord-015569-vy49r1zd 829 11 the the DT cord-015569-vy49r1zd 829 12 hedonic hedonic JJ cord-015569-vy49r1zd 829 13 or or CC cord-015569-vy49r1zd 829 14 emotional emotional JJ cord-015569-vy49r1zd 829 15 component component NN cord-015569-vy49r1zd 829 16 . . . cord-015569-vy49r1zd 830 1 The the DT cord-015569-vy49r1zd 830 2 purpose purpose NN cord-015569-vy49r1zd 830 3 of of IN cord-015569-vy49r1zd 830 4 this this DT cord-015569-vy49r1zd 830 5 study study NN cord-015569-vy49r1zd 830 6 was be VBD cord-015569-vy49r1zd 830 7 to to TO cord-015569-vy49r1zd 830 8 measure measure VB cord-015569-vy49r1zd 830 9 the the DT cord-015569-vy49r1zd 830 10 brain brain NN cord-015569-vy49r1zd 830 11 activity activity NN cord-015569-vy49r1zd 830 12 associated associate VBN cord-015569-vy49r1zd 830 13 with with IN cord-015569-vy49r1zd 830 14 human human JJ cord-015569-vy49r1zd 830 15 olfaction olfaction NN cord-015569-vy49r1zd 830 16 using use VBG cord-015569-vy49r1zd 830 17 functional functional JJ cord-015569-vy49r1zd 830 18 magnetic magnetic JJ cord-015569-vy49r1zd 830 19 resonance resonance NN cord-015569-vy49r1zd 830 20 imaging imaging NN cord-015569-vy49r1zd 830 21 ( ( -LRB- cord-015569-vy49r1zd 830 22 fMRI fMRI NNP cord-015569-vy49r1zd 830 23 ) ) -RRB- cord-015569-vy49r1zd 830 24 and and CC cord-015569-vy49r1zd 830 25 to to TO cord-015569-vy49r1zd 830 26 evaluate evaluate VB cord-015569-vy49r1zd 830 27 the the DT cord-015569-vy49r1zd 830 28 influence influence NN cord-015569-vy49r1zd 830 29 of of IN cord-015569-vy49r1zd 830 30 the the DT cord-015569-vy49r1zd 830 31 pleasantness pleasantness NN cord-015569-vy49r1zd 830 32 of of IN cord-015569-vy49r1zd 830 33 odors odor NNS cord-015569-vy49r1zd 830 34 by by IN cord-015569-vy49r1zd 830 35 complex complex JJ cord-015569-vy49r1zd 830 36 odor odor NN cord-015569-vy49r1zd 830 37 and and CC cord-015569-vy49r1zd 830 38 visual visual JJ cord-015569-vy49r1zd 830 39 stimuli stimulus NNS cord-015569-vy49r1zd 830 40 . . . cord-015569-vy49r1zd 831 1 Seventeen seventeen CD cord-015569-vy49r1zd 831 2 healthy healthy JJ cord-015569-vy49r1zd 831 3 right right RB cord-015569-vy49r1zd 831 4 - - HYPH cord-015569-vy49r1zd 831 5 handed handed JJ cord-015569-vy49r1zd 831 6 subjects subject NNS cord-015569-vy49r1zd 831 7 ( ( -LRB- cord-015569-vy49r1zd 831 8 9 9 CD cord-015569-vy49r1zd 831 9 men man NNS cord-015569-vy49r1zd 831 10 ; ; : cord-015569-vy49r1zd 831 11 8 8 CD cord-015569-vy49r1zd 831 12 women woman NNS cord-015569-vy49r1zd 831 13 ) ) -RRB- cord-015569-vy49r1zd 831 14 with with IN cord-015569-vy49r1zd 831 15 normal normal JJ cord-015569-vy49r1zd 831 16 olfaction olfaction NN cord-015569-vy49r1zd 831 17 participated participate VBD cord-015569-vy49r1zd 831 18 in in IN cord-015569-vy49r1zd 831 19 the the DT cord-015569-vy49r1zd 831 20 study study NN cord-015569-vy49r1zd 831 21 . . . cord-015569-vy49r1zd 832 1 An an DT cord-015569-vy49r1zd 832 2 event event NN cord-015569-vy49r1zd 832 3 - - HYPH cord-015569-vy49r1zd 832 4 related relate VBN cord-015569-vy49r1zd 832 5 MRI MRI NNP cord-015569-vy49r1zd 832 6 method method NN cord-015569-vy49r1zd 832 7 was be VBD cord-015569-vy49r1zd 832 8 used use VBN cord-015569-vy49r1zd 832 9 to to TO cord-015569-vy49r1zd 832 10 analyze analyze VB cord-015569-vy49r1zd 832 11 olfaction olfaction NN cord-015569-vy49r1zd 832 12 - - HYPH cord-015569-vy49r1zd 832 13 induced induce VBN cord-015569-vy49r1zd 832 14 responses response NNS cord-015569-vy49r1zd 832 15 on on IN cord-015569-vy49r1zd 832 16 fMRI fMRI NNP cord-015569-vy49r1zd 832 17 . . . cord-015569-vy49r1zd 833 1 A a DT cord-015569-vy49r1zd 833 2 puff puff NN cord-015569-vy49r1zd 833 3 of of IN cord-015569-vy49r1zd 833 4 odorant odorant NN cord-015569-vy49r1zd 833 5 was be VBD cord-015569-vy49r1zd 833 6 delivered deliver VBN cord-015569-vy49r1zd 833 7 to to IN cord-015569-vy49r1zd 833 8 the the DT cord-015569-vy49r1zd 833 9 nose nose NN cord-015569-vy49r1zd 833 10 of of IN cord-015569-vy49r1zd 833 11 each each DT cord-015569-vy49r1zd 833 12 subject subject NN cord-015569-vy49r1zd 833 13 through through IN cord-015569-vy49r1zd 833 14 a a DT cord-015569-vy49r1zd 833 15 nose nose NN cord-015569-vy49r1zd 833 16 mask mask NN cord-015569-vy49r1zd 833 17 with with IN cord-015569-vy49r1zd 833 18 electrically electrically RB cord-015569-vy49r1zd 833 19 controlled control VBN cord-015569-vy49r1zd 833 20 pneumatic pneumatic JJ cord-015569-vy49r1zd 833 21 valves valve NNS cord-015569-vy49r1zd 833 22 . . . cord-015569-vy49r1zd 834 1 For for IN cord-015569-vy49r1zd 834 2 the the DT cord-015569-vy49r1zd 834 3 event event NN cord-015569-vy49r1zd 834 4 - - HYPH cord-015569-vy49r1zd 834 5 related relate VBN cord-015569-vy49r1zd 834 6 task task NN cord-015569-vy49r1zd 834 7 in in IN cord-015569-vy49r1zd 834 8 the the DT cord-015569-vy49r1zd 834 9 fMRI fMRI NNP cord-015569-vy49r1zd 834 10 experiment experiment NN cord-015569-vy49r1zd 834 11 , , , cord-015569-vy49r1zd 834 12 two two CD cord-015569-vy49r1zd 834 13 odorants odorant NNS cord-015569-vy49r1zd 834 14 ( ( -LRB- cord-015569-vy49r1zd 834 15 pleasant pleasant JJ cord-015569-vy49r1zd 834 16 odor odor NN cord-015569-vy49r1zd 834 17 : : : cord-015569-vy49r1zd 834 18 amyl amyl NN cord-015569-vy49r1zd 834 19 - - HYPH cord-015569-vy49r1zd 834 20 acetate acetate NN cord-015569-vy49r1zd 834 21 , , , cord-015569-vy49r1zd 834 22 unpleasant unpleasant JJ cord-015569-vy49r1zd 834 23 odor odor NN cord-015569-vy49r1zd 834 24 : : : cord-015569-vy49r1zd 834 25 iso iso NN cord-015569-vy49r1zd 834 26 - - HYPH cord-015569-vy49r1zd 834 27 valeric valeric JJ cord-015569-vy49r1zd 834 28 acid acid NN cord-015569-vy49r1zd 834 29 ) ) -RRB- cord-015569-vy49r1zd 834 30 and and CC cord-015569-vy49r1zd 834 31 two two CD cord-015569-vy49r1zd 834 32 types type NNS cord-015569-vy49r1zd 834 33 of of IN cord-015569-vy49r1zd 834 34 visual visual JJ cord-015569-vy49r1zd 834 35 stimuli stimulus NNS cord-015569-vy49r1zd 834 36 ( ( -LRB- cord-015569-vy49r1zd 834 37 pleasant pleasant JJ cord-015569-vy49r1zd 834 38 image image NN cord-015569-vy49r1zd 834 39 , , , cord-015569-vy49r1zd 834 40 unpleasant unpleasant JJ cord-015569-vy49r1zd 834 41 image image NN cord-015569-vy49r1zd 834 42 ) ) -RRB- cord-015569-vy49r1zd 834 43 were be VBD cord-015569-vy49r1zd 834 44 randomly randomly RB cord-015569-vy49r1zd 834 45 presented present VBN cord-015569-vy49r1zd 834 46 . . . cord-015569-vy49r1zd 835 1 Two two CD cord-015569-vy49r1zd 835 2 cross cross JJ cord-015569-vy49r1zd 835 3 - - JJ cord-015569-vy49r1zd 835 4 modal modal JJ cord-015569-vy49r1zd 835 5 sensual sensual JJ cord-015569-vy49r1zd 835 6 interactions interaction NNS cord-015569-vy49r1zd 835 7 were be VBD cord-015569-vy49r1zd 835 8 tested test VBN cord-015569-vy49r1zd 835 9 using use VBG cord-015569-vy49r1zd 835 10 SPM SPM NNP cord-015569-vy49r1zd 835 11 - - HYPH cord-015569-vy49r1zd 835 12 software software NN cord-015569-vy49r1zd 835 13 for for IN cord-015569-vy49r1zd 835 14 both both CC cord-015569-vy49r1zd 835 15 matching matching NN cord-015569-vy49r1zd 835 16 / / SYM cord-015569-vy49r1zd 835 17 mismatching mismatching NN cord-015569-vy49r1zd 835 18 conditions condition NNS cord-015569-vy49r1zd 835 19 and and CC cord-015569-vy49r1zd 835 20 pleasant pleasant JJ cord-015569-vy49r1zd 835 21 / / SYM cord-015569-vy49r1zd 835 22 unpleasant unpleasant JJ cord-015569-vy49r1zd 835 23 conditions condition NNS cord-015569-vy49r1zd 835 24 , , , cord-015569-vy49r1zd 835 25 respectively respectively RB cord-015569-vy49r1zd 835 26 . . . cord-015569-vy49r1zd 836 1 Results result NNS cord-015569-vy49r1zd 836 2 revealed reveal VBD cord-015569-vy49r1zd 836 3 specific specific JJ cord-015569-vy49r1zd 836 4 brain brain NN cord-015569-vy49r1zd 836 5 areas area NNS cord-015569-vy49r1zd 836 6 that that WDT cord-015569-vy49r1zd 836 7 were be VBD cord-015569-vy49r1zd 836 8 activated activate VBN cord-015569-vy49r1zd 836 9 by by IN cord-015569-vy49r1zd 836 10 cross cross JJ cord-015569-vy49r1zd 836 11 - - JJ cord-015569-vy49r1zd 836 12 modal modal JJ cord-015569-vy49r1zd 836 13 interactions interaction NNS cord-015569-vy49r1zd 836 14 with with IN cord-015569-vy49r1zd 836 15 odor odor NN cord-015569-vy49r1zd 836 16 and and CC cord-015569-vy49r1zd 836 17 visual visual JJ cord-015569-vy49r1zd 836 18 stimuli stimulus NNS cord-015569-vy49r1zd 836 19 . . . cord-015569-vy49r1zd 837 1 In in IN cord-015569-vy49r1zd 837 2 advance advance NN cord-015569-vy49r1zd 837 3 of of IN cord-015569-vy49r1zd 837 4 the the DT cord-015569-vy49r1zd 837 5 fMRI fMRI NNP cord-015569-vy49r1zd 837 6 experiment experiment NN cord-015569-vy49r1zd 837 7 , , , cord-015569-vy49r1zd 837 8 psychological psychological JJ cord-015569-vy49r1zd 837 9 odor odor NN cord-015569-vy49r1zd 837 10 experiments experiment NNS cord-015569-vy49r1zd 837 11 ( ( -LRB- cord-015569-vy49r1zd 837 12 cross cross JJ cord-015569-vy49r1zd 837 13 - - JJ cord-015569-vy49r1zd 837 14 modal modal JJ cord-015569-vy49r1zd 837 15 , , , cord-015569-vy49r1zd 837 16 complex complex JJ cord-015569-vy49r1zd 837 17 stimuli stimulus NNS cord-015569-vy49r1zd 837 18 with with IN cord-015569-vy49r1zd 837 19 a a DT cord-015569-vy49r1zd 837 20 visual visual JJ cord-015569-vy49r1zd 837 21 and and CC cord-015569-vy49r1zd 837 22 odor odor NN cord-015569-vy49r1zd 837 23 evaluation evaluation NN cord-015569-vy49r1zd 837 24 test test NN cord-015569-vy49r1zd 837 25 ) ) -RRB- cord-015569-vy49r1zd 837 26 were be VBD cord-015569-vy49r1zd 837 27 conducted conduct VBN cord-015569-vy49r1zd 837 28 using use VBG cord-015569-vy49r1zd 837 29 a a DT cord-015569-vy49r1zd 837 30 subjective subjective JJ cord-015569-vy49r1zd 837 31 judgment judgment NN cord-015569-vy49r1zd 837 32 method method NN cord-015569-vy49r1zd 837 33 or or CC cord-015569-vy49r1zd 837 34 pleasantness pleasantness NN cord-015569-vy49r1zd 837 35 / / SYM cord-015569-vy49r1zd 837 36 unpleasantness unpleasantness NN cord-015569-vy49r1zd 837 37 , , , cord-015569-vy49r1zd 837 38 respectively respectively RB cord-015569-vy49r1zd 837 39 . . . cord-015569-vy49r1zd 838 1 Based base VBN cord-015569-vy49r1zd 838 2 on on IN cord-015569-vy49r1zd 838 3 the the DT cord-015569-vy49r1zd 838 4 fMRI fmri NN cord-015569-vy49r1zd 838 5 and and CC cord-015569-vy49r1zd 838 6 psychological psychological JJ cord-015569-vy49r1zd 838 7 experiments experiment NNS cord-015569-vy49r1zd 838 8 , , , cord-015569-vy49r1zd 838 9 we -PRON- PRP cord-015569-vy49r1zd 838 10 estimated estimate VBD cord-015569-vy49r1zd 838 11 the the DT cord-015569-vy49r1zd 838 12 most most RBS cord-015569-vy49r1zd 838 13 suitable suitable JJ cord-015569-vy49r1zd 838 14 conditions condition NNS cord-015569-vy49r1zd 838 15 for for IN cord-015569-vy49r1zd 838 16 evaluating evaluate VBG cord-015569-vy49r1zd 838 17 the the DT cord-015569-vy49r1zd 838 18 pleasantness pleasantness NN cord-015569-vy49r1zd 838 19 of of IN cord-015569-vy49r1zd 838 20 odors odor NNS cord-015569-vy49r1zd 838 21 . . . cord-015569-vy49r1zd 839 1 From from IN cord-015569-vy49r1zd 839 2 analysis analysis NN cord-015569-vy49r1zd 839 3 of of IN cord-015569-vy49r1zd 839 4 the the DT cord-015569-vy49r1zd 839 5 fMRI fMRI NNP cord-015569-vy49r1zd 839 6 experiments experiment NNS cord-015569-vy49r1zd 839 7 , , , cord-015569-vy49r1zd 839 8 two two CD cord-015569-vy49r1zd 839 9 responses response NNS cord-015569-vy49r1zd 839 10 ( ( -LRB- cord-015569-vy49r1zd 839 11 1 1 CD cord-015569-vy49r1zd 839 12 : : : cord-015569-vy49r1zd 839 13 emotional emotional JJ cord-015569-vy49r1zd 839 14 response response NN cord-015569-vy49r1zd 839 15 to to IN cord-015569-vy49r1zd 839 16 pleasantness pleasantness NN cord-015569-vy49r1zd 839 17 / / SYM cord-015569-vy49r1zd 839 18 unpleasantness unpleasantness NN cord-015569-vy49r1zd 839 19 , , , cord-015569-vy49r1zd 839 20 and and CC cord-015569-vy49r1zd 839 21 2 2 CD cord-015569-vy49r1zd 839 22 : : : cord-015569-vy49r1zd 839 23 response response NN cord-015569-vy49r1zd 839 24 to to IN cord-015569-vy49r1zd 839 25 matching/ matching/ CD cord-015569-vy49r1zd 839 26 mismatching mismatching NN cord-015569-vy49r1zd 839 27 ) ) -RRB- cord-015569-vy49r1zd 839 28 were be VBD cord-015569-vy49r1zd 839 29 obtained obtain VBN cord-015569-vy49r1zd 839 30 with with IN cord-015569-vy49r1zd 839 31 the the DT cord-015569-vy49r1zd 839 32 cross cross JJ cord-015569-vy49r1zd 839 33 - - JJ cord-015569-vy49r1zd 839 34 modal modal JJ cord-015569-vy49r1zd 839 35 , , , cord-015569-vy49r1zd 839 36 complex complex JJ cord-015569-vy49r1zd 839 37 stimuli stimulus NNS cord-015569-vy49r1zd 839 38 using use VBG cord-015569-vy49r1zd 839 39 odors odor NNS cord-015569-vy49r1zd 839 40 and and CC cord-015569-vy49r1zd 839 41 images image NNS cord-015569-vy49r1zd 839 42 . . . cord-015569-vy49r1zd 840 1 From from IN cord-015569-vy49r1zd 840 2 the the DT cord-015569-vy49r1zd 840 3 analysis analysis NN cord-015569-vy49r1zd 840 4 of of IN cord-015569-vy49r1zd 840 5 our -PRON- PRP$ cord-015569-vy49r1zd 840 6 experiments experiment NNS cord-015569-vy49r1zd 840 7 , , , cord-015569-vy49r1zd 840 8 activity activity NN cord-015569-vy49r1zd 840 9 associated associate VBN cord-015569-vy49r1zd 840 10 with with IN cord-015569-vy49r1zd 840 11 the the DT cord-015569-vy49r1zd 840 12 response response NN cord-015569-vy49r1zd 840 13 to to IN cord-015569-vy49r1zd 840 14 pleasantness pleasantness NN cord-015569-vy49r1zd 840 15 / / SYM cord-015569-vy49r1zd 840 16 unpleasantness unpleasantness NN cord-015569-vy49r1zd 840 17 was be VBD cord-015569-vy49r1zd 840 18 seen see VBN cord-015569-vy49r1zd 840 19 mainly mainly RB cord-015569-vy49r1zd 840 20 in in IN cord-015569-vy49r1zd 840 21 the the DT cord-015569-vy49r1zd 840 22 right right JJ cord-015569-vy49r1zd 840 23 orbital orbital JJ cord-015569-vy49r1zd 840 24 frontal frontal JJ cord-015569-vy49r1zd 840 25 cerebrum cerebrum NN cord-015569-vy49r1zd 840 26 and and CC cord-015569-vy49r1zd 840 27 the the DT cord-015569-vy49r1zd 840 28 supramarginal supramarginal NNP cord-015569-vy49r1zd 840 29 gyrus gyrus NNP cord-015569-vy49r1zd 840 30 , , , cord-015569-vy49r1zd 840 31 middle middle JJ cord-015569-vy49r1zd 840 32 frontal frontal JJ cord-015569-vy49r1zd 840 33 gyrus gyrus NNP cord-015569-vy49r1zd 840 34 and and CC cord-015569-vy49r1zd 840 35 amygdala amygdala NN cord-015569-vy49r1zd 840 36 . . . cord-015569-vy49r1zd 841 1 On on IN cord-015569-vy49r1zd 841 2 the the DT cord-015569-vy49r1zd 841 3 other other JJ cord-015569-vy49r1zd 841 4 hand hand NN cord-015569-vy49r1zd 841 5 , , , cord-015569-vy49r1zd 841 6 activity activity NN cord-015569-vy49r1zd 841 7 associated associate VBN cord-015569-vy49r1zd 841 8 with with IN cord-015569-vy49r1zd 841 9 the the DT cord-015569-vy49r1zd 841 10 response response NN cord-015569-vy49r1zd 841 11 to to IN cord-015569-vy49r1zd 841 12 matching matching NN cord-015569-vy49r1zd 841 13 / / SYM cord-015569-vy49r1zd 841 14 mismatching mismatching NN cord-015569-vy49r1zd 841 15 was be VBD cord-015569-vy49r1zd 841 16 seen see VBN cord-015569-vy49r1zd 841 17 in in IN cord-015569-vy49r1zd 841 18 areas area NNS cord-015569-vy49r1zd 841 19 of of IN cord-015569-vy49r1zd 841 20 the the DT cord-015569-vy49r1zd 841 21 brain brain NN cord-015569-vy49r1zd 841 22 corresponding correspond VBG cord-015569-vy49r1zd 841 23 to to IN cord-015569-vy49r1zd 841 24 memory memory NN cord-015569-vy49r1zd 841 25 and and CC cord-015569-vy49r1zd 841 26 cognition cognition NN cord-015569-vy49r1zd 841 27 . . . cord-015569-vy49r1zd 842 1 Thus thus RB cord-015569-vy49r1zd 842 2 , , , cord-015569-vy49r1zd 842 3 cross cross JJ cord-015569-vy49r1zd 842 4 - - JJ cord-015569-vy49r1zd 842 5 modal modal JJ cord-015569-vy49r1zd 842 6 , , , cord-015569-vy49r1zd 842 7 complex complex JJ cord-015569-vy49r1zd 842 8 effects effect NNS cord-015569-vy49r1zd 842 9 were be VBD cord-015569-vy49r1zd 842 10 suggested suggest VBN cord-015569-vy49r1zd 842 11 to to TO cord-015569-vy49r1zd 842 12 be be VB cord-015569-vy49r1zd 842 13 an an DT cord-015569-vy49r1zd 842 14 emotional emotional JJ cord-015569-vy49r1zd 842 15 response response NN cord-015569-vy49r1zd 842 16 to to IN cord-015569-vy49r1zd 842 17 pleasantness pleasantness NN cord-015569-vy49r1zd 842 18 / / SYM cord-015569-vy49r1zd 842 19 unpleasantness unpleasantness NN cord-015569-vy49r1zd 842 20 and and CC cord-015569-vy49r1zd 842 21 cognitive cognitive JJ cord-015569-vy49r1zd 842 22 and and CC cord-015569-vy49r1zd 842 23 memory memory NN cord-015569-vy49r1zd 842 24 responses response NNS cord-015569-vy49r1zd 842 25 to to IN cord-015569-vy49r1zd 842 26 matching matching NN cord-015569-vy49r1zd 842 27 / / SYM cord-015569-vy49r1zd 842 28 mismatching mismatching NN cord-015569-vy49r1zd 842 29 . . . cord-015569-vy49r1zd 843 1 As as IN cord-015569-vy49r1zd 843 2 otorhinolaryngologists otorhinolaryngologist NNS cord-015569-vy49r1zd 843 3 , , , cord-015569-vy49r1zd 843 4 it -PRON- PRP cord-015569-vy49r1zd 843 5 is be VBZ cord-015569-vy49r1zd 843 6 important important JJ cord-015569-vy49r1zd 843 7 to to TO cord-015569-vy49r1zd 843 8 grasp grasp VB cord-015569-vy49r1zd 843 9 the the DT cord-015569-vy49r1zd 843 10 grade grade NN cord-015569-vy49r1zd 843 11 of of IN cord-015569-vy49r1zd 843 12 subjective subjective JJ cord-015569-vy49r1zd 843 13 symptoms symptom NNS cord-015569-vy49r1zd 843 14 and and CC cord-015569-vy49r1zd 843 15 quality quality NN cord-015569-vy49r1zd 843 16 of of IN cord-015569-vy49r1zd 843 17 life life NN cord-015569-vy49r1zd 843 18 ( ( -LRB- cord-015569-vy49r1zd 843 19 QOL QOL NNP cord-015569-vy49r1zd 843 20 ) ) -RRB- cord-015569-vy49r1zd 843 21 when when WRB cord-015569-vy49r1zd 843 22 we -PRON- PRP cord-015569-vy49r1zd 843 23 examine examine VBP cord-015569-vy49r1zd 843 24 outpatients outpatient NNS cord-015569-vy49r1zd 843 25 with with IN cord-015569-vy49r1zd 843 26 olfactory olfactory JJ cord-015569-vy49r1zd 843 27 dysfunction dysfunction NN cord-015569-vy49r1zd 843 28 . . . cord-015569-vy49r1zd 844 1 However however RB cord-015569-vy49r1zd 844 2 , , , cord-015569-vy49r1zd 844 3 the the DT cord-015569-vy49r1zd 844 4 influence influence NN cord-015569-vy49r1zd 844 5 that that IN cord-015569-vy49r1zd 844 6 the the DT cord-015569-vy49r1zd 844 7 sense sense NN cord-015569-vy49r1zd 844 8 of of IN cord-015569-vy49r1zd 844 9 smell smell NN cord-015569-vy49r1zd 844 10 exerts exert VBZ cord-015569-vy49r1zd 844 11 on on IN cord-015569-vy49r1zd 844 12 the the DT cord-015569-vy49r1zd 844 13 QOL QOL NNP cord-015569-vy49r1zd 844 14 related relate VBN cord-015569-vy49r1zd 844 15 to to IN cord-015569-vy49r1zd 844 16 health health NN cord-015569-vy49r1zd 844 17 is be VBZ cord-015569-vy49r1zd 844 18 not not RB cord-015569-vy49r1zd 844 19 clear clear JJ cord-015569-vy49r1zd 844 20 . . . cord-015569-vy49r1zd 845 1 Therefore therefore RB cord-015569-vy49r1zd 845 2 , , , cord-015569-vy49r1zd 845 3 we -PRON- PRP cord-015569-vy49r1zd 845 4 investigated investigate VBD cord-015569-vy49r1zd 845 5 outpatientsÕ outpatientsÕ NNP cord-015569-vy49r1zd 845 6 QOL QOL NNP cord-015569-vy49r1zd 845 7 using use VBG cord-015569-vy49r1zd 845 8 the the DT cord-015569-vy49r1zd 845 9 ' ' `` cord-015569-vy49r1zd 845 10 ' ' '' cord-015569-vy49r1zd 845 11 Health Health NNP cord-015569-vy49r1zd 845 12 - - HYPH cord-015569-vy49r1zd 845 13 Related relate VBN cord-015569-vy49r1zd 845 14 QOL QOL NNP cord-015569-vy49r1zd 845 15 Measure measure NN cord-015569-vy49r1zd 845 16 ( ( -LRB- cord-015569-vy49r1zd 845 17 SF-36 SF-36 NNP cord-015569-vy49r1zd 845 18 ) ) -RRB- cord-015569-vy49r1zd 845 19 , , , cord-015569-vy49r1zd 845 20 ' ' '' cord-015569-vy49r1zd 845 21 ' ' '' cord-015569-vy49r1zd 845 22 which which WDT cord-015569-vy49r1zd 845 23 is be VBZ cord-015569-vy49r1zd 845 24 widely widely RB cord-015569-vy49r1zd 845 25 used use VBN cord-015569-vy49r1zd 845 26 around around IN cord-015569-vy49r1zd 845 27 the the DT cord-015569-vy49r1zd 845 28 world world NN cord-015569-vy49r1zd 845 29 . . . cord-015569-vy49r1zd 846 1 Concurrently concurrently RB cord-015569-vy49r1zd 846 2 , , , cord-015569-vy49r1zd 846 3 we -PRON- PRP cord-015569-vy49r1zd 846 4 applied apply VBD cord-015569-vy49r1zd 846 5 a a DT cord-015569-vy49r1zd 846 6 1 1 CD cord-015569-vy49r1zd 846 7 ) ) -RRB- cord-015569-vy49r1zd 846 8 visual visual JJ cord-015569-vy49r1zd 846 9 analog analog NN cord-015569-vy49r1zd 846 10 scale scale NN cord-015569-vy49r1zd 846 11 ( ( -LRB- cord-015569-vy49r1zd 846 12 VAS vas NN cord-015569-vy49r1zd 846 13 ) ) -RRB- cord-015569-vy49r1zd 846 14 to to TO cord-015569-vy49r1zd 846 15 grade grade VB cord-015569-vy49r1zd 846 16 subjective subjective JJ cord-015569-vy49r1zd 846 17 symptoms symptom NNS cord-015569-vy49r1zd 846 18 ( ( -LRB- cord-015569-vy49r1zd 846 19 the the DT cord-015569-vy49r1zd 846 20 smell smell NN cord-015569-vy49r1zd 846 21 of of IN cord-015569-vy49r1zd 846 22 food food NN cord-015569-vy49r1zd 846 23 and and CC cord-015569-vy49r1zd 846 24 drink drink NN cord-015569-vy49r1zd 846 25 , , , cord-015569-vy49r1zd 846 26 perfumes perfume NNS cord-015569-vy49r1zd 846 27 , , , cord-015569-vy49r1zd 846 28 excreta excreta NN cord-015569-vy49r1zd 846 29 and and CC cord-015569-vy49r1zd 846 30 gases gas NNS cord-015569-vy49r1zd 846 31 ) ) -RRB- cord-015569-vy49r1zd 846 32 and and CC cord-015569-vy49r1zd 846 33 the the DT cord-015569-vy49r1zd 846 34 deliciousness deliciousness NN cord-015569-vy49r1zd 846 35 of of IN cord-015569-vy49r1zd 846 36 meals meal NNS cord-015569-vy49r1zd 846 37 ( ( -LRB- cord-015569-vy49r1zd 846 38 QOL QOL NNP cord-015569-vy49r1zd 846 39 ) ) -RRB- cord-015569-vy49r1zd 846 40 , , , cord-015569-vy49r1zd 846 41 2 2 CD cord-015569-vy49r1zd 846 42 ) ) -RRB- cord-015569-vy49r1zd 847 1 smell smell NNP cord-015569-vy49r1zd 847 2 questionnaire questionnaire NN cord-015569-vy49r1zd 847 3 for for IN cord-015569-vy49r1zd 847 4 daily daily JJ cord-015569-vy49r1zd 847 5 life life NN cord-015569-vy49r1zd 847 6 , , , cord-015569-vy49r1zd 847 7 3 3 CD cord-015569-vy49r1zd 847 8 ) ) -RRB- cord-015569-vy49r1zd 848 1 T&T t&t NN cord-015569-vy49r1zd 848 2 olfactometry olfactometry NN cord-015569-vy49r1zd 848 3 , , , cord-015569-vy49r1zd 848 4 4 4 CD cord-015569-vy49r1zd 848 5 ) ) -RRB- cord-015569-vy49r1zd 848 6 intravenous intravenous JJ cord-015569-vy49r1zd 848 7 olfaction olfaction NN cord-015569-vy49r1zd 848 8 test test NN cord-015569-vy49r1zd 848 9 ( ( -LRB- cord-015569-vy49r1zd 848 10 Alinamin Alinamin NNP cord-015569-vy49r1zd 848 11 test test NN cord-015569-vy49r1zd 848 12 ) ) -RRB- cord-015569-vy49r1zd 848 13 and and CC cord-015569-vy49r1zd 848 14 5 5 LS cord-015569-vy49r1zd 848 15 ) ) -RRB- cord-015569-vy49r1zd 848 16 card card NN cord-015569-vy49r1zd 848 17 - - HYPH cord-015569-vy49r1zd 848 18 type type NN cord-015569-vy49r1zd 848 19 smell smell NN cord-015569-vy49r1zd 848 20 identification identification NN cord-015569-vy49r1zd 848 21 test test NN cord-015569-vy49r1zd 848 22 ( ( -LRB- cord-015569-vy49r1zd 848 23 Open Open NNP cord-015569-vy49r1zd 848 24 Essence Essence NNP cord-015569-vy49r1zd 848 25 ) ) -RRB- cord-015569-vy49r1zd 848 26 . . . cord-015569-vy49r1zd 849 1 We -PRON- PRP cord-015569-vy49r1zd 849 2 then then RB cord-015569-vy49r1zd 849 3 analyzed analyze VBD cord-015569-vy49r1zd 849 4 those those DT cord-015569-vy49r1zd 849 5 tests test NNS cord-015569-vy49r1zd 849 6 and and CC cord-015569-vy49r1zd 849 7 SF-36 SF-36 NNP cord-015569-vy49r1zd 849 8 for for IN cord-015569-vy49r1zd 849 9 correlations correlation NNS cord-015569-vy49r1zd 849 10 . . . cord-015569-vy49r1zd 850 1 As as IN cord-015569-vy49r1zd 850 2 the the DT cord-015569-vy49r1zd 850 3 results result NNS cord-015569-vy49r1zd 850 4 , , , cord-015569-vy49r1zd 850 5 ' ' '' cord-015569-vy49r1zd 850 6 ' ' '' cord-015569-vy49r1zd 850 7 Vitality Vitality NNP cord-015569-vy49r1zd 850 8 ( ( -LRB- cord-015569-vy49r1zd 850 9 VT VT NNP cord-015569-vy49r1zd 850 10 ) ) -RRB- cord-015569-vy49r1zd 850 11 , , , cord-015569-vy49r1zd 850 12 ' ' '' cord-015569-vy49r1zd 850 13 ' ' '' cord-015569-vy49r1zd 850 14 which which WDT cord-015569-vy49r1zd 850 15 is be VBZ cord-015569-vy49r1zd 850 16 a a DT cord-015569-vy49r1zd 850 17 subscale subscale NN cord-015569-vy49r1zd 850 18 of of IN cord-015569-vy49r1zd 850 19 SF-36 SF-36 NNP cord-015569-vy49r1zd 850 20 , , , cord-015569-vy49r1zd 850 21 correlated correlate VBD cord-015569-vy49r1zd 850 22 weakly weakly RB cord-015569-vy49r1zd 850 23 with with IN cord-015569-vy49r1zd 850 24 the the DT cord-015569-vy49r1zd 850 25 subjective subjective JJ cord-015569-vy49r1zd 850 26 symptom symptom NN cord-015569-vy49r1zd 850 27 VAS vas NN cord-015569-vy49r1zd 850 28 for for IN cord-015569-vy49r1zd 850 29 '' '' '' cord-015569-vy49r1zd 851 1 smell smell NN cord-015569-vy49r1zd 851 2 of of IN cord-015569-vy49r1zd 851 3 perfume perfume NN cord-015569-vy49r1zd 851 4 ' ' '' cord-015569-vy49r1zd 851 5 ' ' '' cord-015569-vy49r1zd 852 1 ( ( -LRB- cord-015569-vy49r1zd 852 2 r r NNP cord-015569-vy49r1zd 852 3 s s NN cord-015569-vy49r1zd 852 4 = = SYM cord-015569-vy49r1zd 852 5 0.262 0.262 CD cord-015569-vy49r1zd 852 6 ) ) -RRB- cord-015569-vy49r1zd 853 1 and and CC cord-015569-vy49r1zd 853 2 the the DT cord-015569-vy49r1zd 853 3 T&T T&T NNP cord-015569-vy49r1zd 853 4 recognition recognition NN cord-015569-vy49r1zd 853 5 threshold threshold NN cord-015569-vy49r1zd 854 1 ( ( -LRB- cord-015569-vy49r1zd 854 2 r r NNP cord-015569-vy49r1zd 854 3 s s NN cord-015569-vy49r1zd 854 4 = = SYM cord-015569-vy49r1zd 854 5 0.203 0.203 CD cord-015569-vy49r1zd 854 6 ) ) -RRB- cord-015569-vy49r1zd 854 7 . . . cord-015569-vy49r1zd 854 8 ' ' '' cord-015569-vy49r1zd 855 1 ' ' `` cord-015569-vy49r1zd 855 2 Role role NN cord-015569-vy49r1zd 855 3 functioning function VBG cord-015569-vy49r1zd 855 4 emotional emotional JJ cord-015569-vy49r1zd 855 5 ( ( -LRB- cord-015569-vy49r1zd 855 6 RE RE NNP cord-015569-vy49r1zd 855 7 ) ) -RRB- cord-015569-vy49r1zd 855 8 , , , cord-015569-vy49r1zd 855 9 ' ' '' cord-015569-vy49r1zd 855 10 ' ' '' cord-015569-vy49r1zd 855 11 which which WDT cord-015569-vy49r1zd 855 12 is be VBZ cord-015569-vy49r1zd 855 13 another another DT cord-015569-vy49r1zd 855 14 subscale subscale NN cord-015569-vy49r1zd 855 15 of of IN cord-015569-vy49r1zd 855 16 SF36 SF36 NNP cord-015569-vy49r1zd 855 17 , , , cord-015569-vy49r1zd 855 18 correlated correlate VBD cord-015569-vy49r1zd 855 19 weakly weakly RB cord-015569-vy49r1zd 855 20 with with IN cord-015569-vy49r1zd 855 21 the the DT cord-015569-vy49r1zd 855 22 subjective subjective JJ cord-015569-vy49r1zd 855 23 symptom symptom NN cord-015569-vy49r1zd 855 24 VAS vas NN cord-015569-vy49r1zd 855 25 for for IN cord-015569-vy49r1zd 855 26 each each DT cord-015569-vy49r1zd 855 27 of of IN cord-015569-vy49r1zd 855 28 ' ' `` cord-015569-vy49r1zd 855 29 ' ' '' cord-015569-vy49r1zd 855 30 smell smell NN cord-015569-vy49r1zd 855 31 of of IN cord-015569-vy49r1zd 855 32 food food NN cord-015569-vy49r1zd 855 33 and and CC cord-015569-vy49r1zd 855 34 drink drink NN cord-015569-vy49r1zd 855 35 ' ' '' cord-015569-vy49r1zd 855 36 ' ' '' cord-015569-vy49r1zd 856 1 ( ( -LRB- cord-015569-vy49r1zd 856 2 r r NNP cord-015569-vy49r1zd 856 3 s s NN cord-015569-vy49r1zd 856 4 = = NN cord-015569-vy49r1zd 856 5 0.234 0.234 CD cord-015569-vy49r1zd 856 6 ) ) -RRB- cord-015569-vy49r1zd 856 7 , , , cord-015569-vy49r1zd 856 8 ' ' '' cord-015569-vy49r1zd 856 9 ' ' '' cord-015569-vy49r1zd 856 10 smell smell NN cord-015569-vy49r1zd 856 11 of of IN cord-015569-vy49r1zd 856 12 perfume perfume NN cord-015569-vy49r1zd 856 13 ' ' '' cord-015569-vy49r1zd 856 14 ' ' '' cord-015569-vy49r1zd 857 1 ( ( -LRB- cord-015569-vy49r1zd 857 2 r r NNP cord-015569-vy49r1zd 857 3 s s NN cord-015569-vy49r1zd 857 4 = = SYM cord-015569-vy49r1zd 857 5 0.272 0.272 CD cord-015569-vy49r1zd 857 6 ) ) -RRB- cord-015569-vy49r1zd 858 1 and and CC cord-015569-vy49r1zd 858 2 ' ' `` cord-015569-vy49r1zd 858 3 ' ' '' cord-015569-vy49r1zd 858 4 smell smell NN cord-015569-vy49r1zd 858 5 of of IN cord-015569-vy49r1zd 858 6 gas gas NN cord-015569-vy49r1zd 858 7 ' ' '' cord-015569-vy49r1zd 858 8 ' ' '' cord-015569-vy49r1zd 859 1 ( ( -LRB- cord-015569-vy49r1zd 859 2 r r NNP cord-015569-vy49r1zd 859 3 s s NN cord-015569-vy49r1zd 859 4 = = SYM cord-015569-vy49r1zd 859 5 0.222 0.222 CD cord-015569-vy49r1zd 859 6 ) ) -RRB- cord-015569-vy49r1zd 859 7 . . . cord-015569-vy49r1zd 860 1 No no DT cord-015569-vy49r1zd 860 2 other other JJ cord-015569-vy49r1zd 860 3 correlation correlation NN cord-015569-vy49r1zd 860 4 was be VBD cord-015569-vy49r1zd 860 5 found find VBN cord-015569-vy49r1zd 860 6 for for IN cord-015569-vy49r1zd 860 7 any any DT cord-015569-vy49r1zd 860 8 of of IN cord-015569-vy49r1zd 860 9 the the DT cord-015569-vy49r1zd 860 10 olfactory olfactory JJ cord-015569-vy49r1zd 860 11 tests test NNS cord-015569-vy49r1zd 860 12 . . . cord-015569-vy49r1zd 861 1 These these DT cord-015569-vy49r1zd 861 2 results result NNS cord-015569-vy49r1zd 861 3 showed show VBD cord-015569-vy49r1zd 861 4 that that IN cord-015569-vy49r1zd 861 5 , , , cord-015569-vy49r1zd 861 6 although although IN cord-015569-vy49r1zd 861 7 olfactory olfactory JJ cord-015569-vy49r1zd 861 8 dysfunction dysfunction NN cord-015569-vy49r1zd 861 9 affected affect VBD cord-015569-vy49r1zd 861 10 the the DT cord-015569-vy49r1zd 861 11 VT VT NNP cord-015569-vy49r1zd 861 12 and and CC cord-015569-vy49r1zd 861 13 RE RE NNP cord-015569-vy49r1zd 861 14 of of IN cord-015569-vy49r1zd 861 15 the the DT cord-015569-vy49r1zd 861 16 patientsÕ patientsÕ NNP cord-015569-vy49r1zd 861 17 health health NN cord-015569-vy49r1zd 861 18 - - HYPH cord-015569-vy49r1zd 861 19 related relate VBN cord-015569-vy49r1zd 861 20 QOL QOL NNP cord-015569-vy49r1zd 861 21 , , , cord-015569-vy49r1zd 861 22 it -PRON- PRP cord-015569-vy49r1zd 861 23 was be VBD cord-015569-vy49r1zd 861 24 very very RB cord-015569-vy49r1zd 861 25 slight slight JJ cord-015569-vy49r1zd 861 26 . . . cord-015569-vy49r1zd 862 1 Even even RB cord-015569-vy49r1zd 862 2 if if IN cord-015569-vy49r1zd 862 3 olfactory olfactory JJ cord-015569-vy49r1zd 862 4 dysfunction dysfunction NN cord-015569-vy49r1zd 862 5 develops develop VBZ cord-015569-vy49r1zd 862 6 , , , cord-015569-vy49r1zd 862 7 the the DT cord-015569-vy49r1zd 862 8 effect effect NN cord-015569-vy49r1zd 862 9 on on IN cord-015569-vy49r1zd 862 10 the the DT cord-015569-vy49r1zd 862 11 overall overall JJ cord-015569-vy49r1zd 862 12 QOL QOL NNP cord-015569-vy49r1zd 862 13 of of IN cord-015569-vy49r1zd 862 14 the the DT cord-015569-vy49r1zd 862 15 patient patient NN cord-015569-vy49r1zd 862 16 is be VBZ cord-015569-vy49r1zd 862 17 slight slight JJ cord-015569-vy49r1zd 862 18 compared compare VBN cord-015569-vy49r1zd 862 19 with with IN cord-015569-vy49r1zd 862 20 other other JJ cord-015569-vy49r1zd 862 21 diseases disease NNS cord-015569-vy49r1zd 862 22 . . . cord-015569-vy49r1zd 863 1 This this DT cord-015569-vy49r1zd 863 2 likely likely RB cord-015569-vy49r1zd 863 3 explains explain VBZ cord-015569-vy49r1zd 863 4 why why WRB cord-015569-vy49r1zd 863 5 these these DT cord-015569-vy49r1zd 863 6 patients patient NNS cord-015569-vy49r1zd 863 7 are be VBP cord-015569-vy49r1zd 863 8 slow slow JJ cord-015569-vy49r1zd 863 9 to to TO cord-015569-vy49r1zd 863 10 consult consult VB cord-015569-vy49r1zd 863 11 a a DT cord-015569-vy49r1zd 863 12 doctor doctor NN cord-015569-vy49r1zd 863 13 . . . cord-015569-vy49r1zd 864 1 ½Introduction ½Introduction NNP cord-015569-vy49r1zd 864 2 Olfactory olfactory JJ cord-015569-vy49r1zd 864 3 dysfunction dysfunction NN cord-015569-vy49r1zd 864 4 is be VBZ cord-015569-vy49r1zd 864 5 most most RBS cord-015569-vy49r1zd 864 6 commonly commonly RB cord-015569-vy49r1zd 864 7 caused cause VBN cord-015569-vy49r1zd 864 8 by by IN cord-015569-vy49r1zd 864 9 chronic chronic JJ cord-015569-vy49r1zd 864 10 rhinosinusitis rhinosinusitis NNP cord-015569-vy49r1zd 864 11 ( ( -LRB- cord-015569-vy49r1zd 864 12 CRS CRS NNP cord-015569-vy49r1zd 864 13 ) ) -RRB- cord-015569-vy49r1zd 864 14 in in IN cord-015569-vy49r1zd 864 15 Japan Japan NNP cord-015569-vy49r1zd 864 16 . . . cord-015569-vy49r1zd 865 1 Within within IN cord-015569-vy49r1zd 865 2 CRS CRS NNP cord-015569-vy49r1zd 865 3 , , , cord-015569-vy49r1zd 865 4 eosinophilic eosinophilic JJ cord-015569-vy49r1zd 865 5 chronic chronic JJ cord-015569-vy49r1zd 865 6 rhinosinusitis rhinosinusitis NN cord-015569-vy49r1zd 865 7 ( ( -LRB- cord-015569-vy49r1zd 865 8 ECRS ECRS NNP cord-015569-vy49r1zd 865 9 ) ) -RRB- cord-015569-vy49r1zd 865 10 is be VBZ cord-015569-vy49r1zd 865 11 said say VBN cord-015569-vy49r1zd 865 12 to to TO cord-015569-vy49r1zd 865 13 cause cause VB cord-015569-vy49r1zd 865 14 severe severe JJ cord-015569-vy49r1zd 865 15 olfactory olfactory JJ cord-015569-vy49r1zd 865 16 dysfunction dysfunction NN cord-015569-vy49r1zd 865 17 . . . cord-015569-vy49r1zd 866 1 However however RB cord-015569-vy49r1zd 866 2 , , , cord-015569-vy49r1zd 866 3 there there EX cord-015569-vy49r1zd 866 4 have have VBP cord-015569-vy49r1zd 866 5 been be VBN cord-015569-vy49r1zd 866 6 few few JJ cord-015569-vy49r1zd 866 7 reports report NNS cord-015569-vy49r1zd 866 8 that that WDT cord-015569-vy49r1zd 866 9 have have VBP cord-015569-vy49r1zd 866 10 compared compare VBN cord-015569-vy49r1zd 866 11 ECRS ECRS NNP cord-015569-vy49r1zd 866 12 with with IN cord-015569-vy49r1zd 866 13 non non JJ cord-015569-vy49r1zd 866 14 eosinophilic eosinophilic JJ cord-015569-vy49r1zd 866 15 chronic chronic JJ cord-015569-vy49r1zd 866 16 rhinosinusitis rhinosinusitis NN cord-015569-vy49r1zd 866 17 ( ( -LRB- cord-015569-vy49r1zd 866 18 NECRS NECRS NNP cord-015569-vy49r1zd 866 19 ) ) -RRB- cord-015569-vy49r1zd 866 20 . . . cord-015569-vy49r1zd 867 1 ½Patients ½patient NNS cord-015569-vy49r1zd 867 2 and and CC cord-015569-vy49r1zd 867 3 Methods method NNS cord-015569-vy49r1zd 868 1 A a DT cord-015569-vy49r1zd 868 2 prospective prospective JJ cord-015569-vy49r1zd 868 3 study study NN cord-015569-vy49r1zd 868 4 was be VBD cord-015569-vy49r1zd 868 5 carried carry VBN cord-015569-vy49r1zd 868 6 out out RP cord-015569-vy49r1zd 868 7 at at IN cord-015569-vy49r1zd 868 8 three three CD cord-015569-vy49r1zd 868 9 institutions institution NNS cord-015569-vy49r1zd 868 10 . . . cord-015569-vy49r1zd 869 1 A a DT cord-015569-vy49r1zd 869 2 total total NN cord-015569-vy49r1zd 869 3 of of IN cord-015569-vy49r1zd 869 4 621 621 CD cord-015569-vy49r1zd 869 5 patients patient NNS cord-015569-vy49r1zd 869 6 underwent undergo VBD cord-015569-vy49r1zd 869 7 endoscopic endoscopic JJ cord-015569-vy49r1zd 869 8 sinus sinus NN cord-015569-vy49r1zd 869 9 surgery surgery NN cord-015569-vy49r1zd 869 10 between between IN cord-015569-vy49r1zd 869 11 April April NNP cord-015569-vy49r1zd 869 12 2007 2007 CD cord-015569-vy49r1zd 869 13 and and CC cord-015569-vy49r1zd 869 14 March March NNP cord-015569-vy49r1zd 869 15 2008 2008 CD cord-015569-vy49r1zd 869 16 and and CC cord-015569-vy49r1zd 869 17 were be VBD cord-015569-vy49r1zd 869 18 pathologically pathologically RB cord-015569-vy49r1zd 869 19 diagnosed diagnose VBN cord-015569-vy49r1zd 869 20 with with IN cord-015569-vy49r1zd 869 21 CRS CRS NNP cord-015569-vy49r1zd 869 22 . . . cord-015569-vy49r1zd 870 1 Of of IN cord-015569-vy49r1zd 870 2 those those DT cord-015569-vy49r1zd 870 3 , , , cord-015569-vy49r1zd 870 4 464 464 CD cord-015569-vy49r1zd 870 5 patients patient NNS cord-015569-vy49r1zd 870 6 ( ( -LRB- cord-015569-vy49r1zd 870 7 318 318 CD cord-015569-vy49r1zd 870 8 males male NNS cord-015569-vy49r1zd 870 9 , , , cord-015569-vy49r1zd 870 10 146 146 CD cord-015569-vy49r1zd 870 11 females female NNS cord-015569-vy49r1zd 870 12 ; ; : cord-015569-vy49r1zd 870 13 mean mean VB cord-015569-vy49r1zd 870 14 age age NN cord-015569-vy49r1zd 870 15 : : : cord-015569-vy49r1zd 870 16 48.2 48.2 CD cord-015569-vy49r1zd 870 17 years year NNS cord-015569-vy49r1zd 870 18 ) ) -RRB- cord-015569-vy49r1zd 870 19 were be VBD cord-015569-vy49r1zd 870 20 included include VBN cord-015569-vy49r1zd 870 21 in in IN cord-015569-vy49r1zd 870 22 this this DT cord-015569-vy49r1zd 870 23 study study NN cord-015569-vy49r1zd 870 24 because because IN cord-015569-vy49r1zd 870 25 they -PRON- PRP cord-015569-vy49r1zd 870 26 had have VBD cord-015569-vy49r1zd 870 27 undergone undergo VBN cord-015569-vy49r1zd 870 28 olfactory olfactory JJ cord-015569-vy49r1zd 870 29 evaluation evaluation NN cord-015569-vy49r1zd 870 30 preoperatively preoperatively NN cord-015569-vy49r1zd 870 31 . . . cord-015569-vy49r1zd 871 1 Olfactory olfactory JJ cord-015569-vy49r1zd 871 2 dysfunction dysfunction NN cord-015569-vy49r1zd 871 3 was be VBD cord-015569-vy49r1zd 871 4 assessed assess VBN cord-015569-vy49r1zd 871 5 using use VBG cord-015569-vy49r1zd 871 6 the the DT cord-015569-vy49r1zd 871 7 standard standard JJ cord-015569-vy49r1zd 871 8 olfactory olfactory JJ cord-015569-vy49r1zd 871 9 threshold threshold NN cord-015569-vy49r1zd 871 10 test test NN cord-015569-vy49r1zd 871 11 ( ( -LRB- cord-015569-vy49r1zd 871 12 T&T t&t NN cord-015569-vy49r1zd 871 13 ) ) -RRB- cord-015569-vy49r1zd 871 14 and and CC cord-015569-vy49r1zd 871 15 subjective subjective JJ cord-015569-vy49r1zd 871 16 symptom symptom NN cord-015569-vy49r1zd 871 17 score score NN cord-015569-vy49r1zd 871 18 ( ( -LRB- cord-015569-vy49r1zd 871 19 0;6 0;6 CD cord-015569-vy49r1zd 871 20 ) ) -RRB- cord-015569-vy49r1zd 871 21 . . . cord-015569-vy49r1zd 872 1 Data datum NNS cord-015569-vy49r1zd 872 2 were be VBD cord-015569-vy49r1zd 872 3 analyzed analyze VBN cord-015569-vy49r1zd 872 4 using use VBG cord-015569-vy49r1zd 872 5 SPSS SPSS NNP cord-015569-vy49r1zd 872 6 software software NN cord-015569-vy49r1zd 872 7 ver ver NN cord-015569-vy49r1zd 872 8 . . . cord-015569-vy49r1zd 873 1 11 11 CD cord-015569-vy49r1zd 873 2 . . . cord-015569-vy49r1zd 874 1 ½Results ½Results NNP cord-015569-vy49r1zd 875 1 The the DT cord-015569-vy49r1zd 875 2 464 464 CD cord-015569-vy49r1zd 875 3 patients patient NNS cord-015569-vy49r1zd 875 4 consisted consist VBD cord-015569-vy49r1zd 875 5 of of IN cord-015569-vy49r1zd 875 6 228 228 CD cord-015569-vy49r1zd 875 7 NECRS NECRS NNP cord-015569-vy49r1zd 875 8 patients patient NNS cord-015569-vy49r1zd 875 9 , , , cord-015569-vy49r1zd 875 10 190 190 CD cord-015569-vy49r1zd 875 11 ECRS ecr NNS cord-015569-vy49r1zd 875 12 patients patient NNS cord-015569-vy49r1zd 875 13 , , , cord-015569-vy49r1zd 875 14 21 21 CD cord-015569-vy49r1zd 875 15 patients patient NNS cord-015569-vy49r1zd 875 16 with with IN cord-015569-vy49r1zd 875 17 allergic allergic JJ cord-015569-vy49r1zd 875 18 fungal fungal NN cord-015569-vy49r1zd 875 19 rhinosinusitis rhinosinusitis NN cord-015569-vy49r1zd 875 20 ( ( -LRB- cord-015569-vy49r1zd 875 21 AFRS AFRS NNP cord-015569-vy49r1zd 875 22 ) ) -RRB- cord-015569-vy49r1zd 875 23 , , , cord-015569-vy49r1zd 875 24 13 13 CD cord-015569-vy49r1zd 875 25 patients patient NNS cord-015569-vy49r1zd 875 26 with with IN cord-015569-vy49r1zd 875 27 odontogenic odontogenic JJ cord-015569-vy49r1zd 875 28 maxillary maxillary JJ cord-015569-vy49r1zd 875 29 sinusitis sinusitis NN cord-015569-vy49r1zd 875 30 and and CC cord-015569-vy49r1zd 875 31 12 12 CD cord-015569-vy49r1zd 875 32 patients patient NNS cord-015569-vy49r1zd 875 33 with with IN cord-015569-vy49r1zd 875 34 fungal fungal JJ cord-015569-vy49r1zd 875 35 rhinosinusitis rhinosinusitis NN cord-015569-vy49r1zd 875 36 . . . cord-015569-vy49r1zd 876 1 T&T T&T NNP cord-015569-vy49r1zd 876 2 found find VBD cord-015569-vy49r1zd 876 3 that that IN cord-015569-vy49r1zd 876 4 54.9 54.9 CD cord-015569-vy49r1zd 876 5 % % NN cord-015569-vy49r1zd 876 6 of of IN cord-015569-vy49r1zd 876 7 the the DT cord-015569-vy49r1zd 876 8 total total JJ cord-015569-vy49r1zd 876 9 patients patient NNS cord-015569-vy49r1zd 876 10 had have VBD cord-015569-vy49r1zd 876 11 olfactory olfactory JJ cord-015569-vy49r1zd 876 12 dysfunction dysfunction NN cord-015569-vy49r1zd 876 13 with with IN cord-015569-vy49r1zd 876 14 a a DT cord-015569-vy49r1zd 876 15 mean mean JJ cord-015569-vy49r1zd 876 16 recognition recognition NN cord-015569-vy49r1zd 876 17 threshold threshold NN cord-015569-vy49r1zd 876 18 of of IN cord-015569-vy49r1zd 876 19 ‡4.1 ‡4.1 NN cord-015569-vy49r1zd 876 20 ( ( -LRB- cord-015569-vy49r1zd 876 21 107 107 CD cord-015569-vy49r1zd 876 22 of of IN cord-015569-vy49r1zd 876 23 228 228 CD cord-015569-vy49r1zd 876 24 NECRS NECRS NNP cord-015569-vy49r1zd 876 25 patients patient NNS cord-015569-vy49r1zd 876 26 ; ; : cord-015569-vy49r1zd 876 27 46.9 46.9 CD cord-015569-vy49r1zd 876 28 % % NN cord-015569-vy49r1zd 876 29 , , , cord-015569-vy49r1zd 876 30 119 119 CD cord-015569-vy49r1zd 876 31 of of IN cord-015569-vy49r1zd 876 32 190 190 CD cord-015569-vy49r1zd 876 33 ECRS ecr NNS cord-015569-vy49r1zd 876 34 patients patient NNS cord-015569-vy49r1zd 876 35 ; ; : cord-015569-vy49r1zd 876 36 62.6 62.6 CD cord-015569-vy49r1zd 876 37 % % NN cord-015569-vy49r1zd 876 38 ) ) -RRB- cord-015569-vy49r1zd 876 39 , , , cord-015569-vy49r1zd 876 40 while while IN cord-015569-vy49r1zd 876 41 57.2 57.2 CD cord-015569-vy49r1zd 876 42 % % NN cord-015569-vy49r1zd 876 43 of of IN cord-015569-vy49r1zd 876 44 the the DT cord-015569-vy49r1zd 876 45 total total JJ cord-015569-vy49r1zd 876 46 patients patient NNS cord-015569-vy49r1zd 876 47 had have VBD cord-015569-vy49r1zd 876 48 olfactory olfactory JJ cord-015569-vy49r1zd 876 49 dysfunction dysfunction NN cord-015569-vy49r1zd 876 50 with with IN cord-015569-vy49r1zd 876 51 a a DT cord-015569-vy49r1zd 876 52 subjective subjective JJ cord-015569-vy49r1zd 876 53 symptom symptom NN cord-015569-vy49r1zd 876 54 score score NN cord-015569-vy49r1zd 876 55 of of IN cord-015569-vy49r1zd 876 56 ‡ ‡ NNP cord-015569-vy49r1zd 876 57 3 3 CD cord-015569-vy49r1zd 876 58 ( ( -LRB- cord-015569-vy49r1zd 876 59 100 100 CD cord-015569-vy49r1zd 876 60 of of IN cord-015569-vy49r1zd 876 61 NECRS NECRS NNP cord-015569-vy49r1zd 876 62 228 228 CD cord-015569-vy49r1zd 876 63 patients patient NNS cord-015569-vy49r1zd 876 64 ; ; : cord-015569-vy49r1zd 876 65 43.9 43.9 CD cord-015569-vy49r1zd 876 66 % % NN cord-015569-vy49r1zd 876 67 , , , cord-015569-vy49r1zd 876 68 135 135 CD cord-015569-vy49r1zd 876 69 of of IN cord-015569-vy49r1zd 876 70 190 190 CD cord-015569-vy49r1zd 876 71 ECRS ecr NNS cord-015569-vy49r1zd 876 72 patients patient NNS cord-015569-vy49r1zd 876 73 ; ; : cord-015569-vy49r1zd 876 74 71.1 71.1 CD cord-015569-vy49r1zd 876 75 % % NN cord-015569-vy49r1zd 876 76 ) ) -RRB- cord-015569-vy49r1zd 876 77 . . . cord-015569-vy49r1zd 877 1 Both both DT cord-015569-vy49r1zd 877 2 the the DT cord-015569-vy49r1zd 877 3 T&T t&t NN cord-015569-vy49r1zd 877 4 result result NN cord-015569-vy49r1zd 877 5 ( ( -LRB- cord-015569-vy49r1zd 877 6 OR or CC cord-015569-vy49r1zd 877 7 : : : cord-015569-vy49r1zd 877 8 1.895 1.895 CD cord-015569-vy49r1zd 877 9 ) ) -RRB- cord-015569-vy49r1zd 877 10 and and CC cord-015569-vy49r1zd 877 11 the the DT cord-015569-vy49r1zd 877 12 subjective subjective JJ cord-015569-vy49r1zd 877 13 symptom symptom NN cord-015569-vy49r1zd 877 14 score score NN cord-015569-vy49r1zd 877 15 ( ( -LRB- cord-015569-vy49r1zd 877 16 OR or NN cord-015569-vy49r1zd 877 17 : : : cord-015569-vy49r1zd 877 18 3.309 3.309 CD cord-015569-vy49r1zd 877 19 ) ) -RRB- cord-015569-vy49r1zd 877 20 were be VBD cord-015569-vy49r1zd 877 21 significantly significantly RB cord-015569-vy49r1zd 877 22 worse bad JJR cord-015569-vy49r1zd 877 23 in in IN cord-015569-vy49r1zd 877 24 the the DT cord-015569-vy49r1zd 877 25 ECRS ECRS NNP cord-015569-vy49r1zd 877 26 patients patient NNS cord-015569-vy49r1zd 877 27 than than IN cord-015569-vy49r1zd 877 28 in in IN cord-015569-vy49r1zd 877 29 the the DT cord-015569-vy49r1zd 877 30 NECRS NECRS NNP cord-015569-vy49r1zd 877 31 patients patient NNS cord-015569-vy49r1zd 877 32 . . . cord-015569-vy49r1zd 878 1 [ [ -LRB- cord-015569-vy49r1zd 878 2 Introduction introduction NN cord-015569-vy49r1zd 878 3 ] ] -RRB- cord-015569-vy49r1zd 879 1 We -PRON- PRP cord-015569-vy49r1zd 879 2 investigated investigate VBD cord-015569-vy49r1zd 879 3 the the DT cord-015569-vy49r1zd 879 4 hypothesis hypothesis NN cord-015569-vy49r1zd 879 5 that that IN cord-015569-vy49r1zd 879 6 the the DT cord-015569-vy49r1zd 879 7 prognosis prognosis NN cord-015569-vy49r1zd 879 8 of of IN cord-015569-vy49r1zd 879 9 olfactory olfactory JJ cord-015569-vy49r1zd 879 10 dysfunction dysfunction NN cord-015569-vy49r1zd 879 11 ( ( -LRB- cord-015569-vy49r1zd 879 12 OD OD NNP cord-015569-vy49r1zd 879 13 ) ) -RRB- cord-015569-vy49r1zd 879 14 due due IN cord-015569-vy49r1zd 879 15 to to IN cord-015569-vy49r1zd 879 16 chronic chronic JJ cord-015569-vy49r1zd 879 17 rhinosinusitis rhinosinusitis NN cord-015569-vy49r1zd 879 18 ( ( -LRB- cord-015569-vy49r1zd 879 19 CRS CRS NNP cord-015569-vy49r1zd 879 20 ) ) -RRB- cord-015569-vy49r1zd 879 21 becomes become VBZ cord-015569-vy49r1zd 879 22 worse bad JJR cord-015569-vy49r1zd 879 23 as as IN cord-015569-vy49r1zd 879 24 the the DT cord-015569-vy49r1zd 879 25 duration duration NN cord-015569-vy49r1zd 879 26 of of IN cord-015569-vy49r1zd 879 27 OD OD NNP cord-015569-vy49r1zd 879 28 becomes become VBZ cord-015569-vy49r1zd 879 29 longer long RBR cord-015569-vy49r1zd 879 30 . . . cord-015569-vy49r1zd 880 1 [ [ -LRB- cord-015569-vy49r1zd 880 2 Patients patient NNS cord-015569-vy49r1zd 880 3 and and CC cord-015569-vy49r1zd 880 4 Methods Methods NNPS cord-015569-vy49r1zd 880 5 ] ] -RRB- cord-015569-vy49r1zd 880 6 113 113 CD cord-015569-vy49r1zd 880 7 patients patient NNS cord-015569-vy49r1zd 880 8 ( ( -LRB- cord-015569-vy49r1zd 880 9 70 70 CD cord-015569-vy49r1zd 880 10 males male NNS cord-015569-vy49r1zd 880 11 , , , cord-015569-vy49r1zd 880 12 43 43 CD cord-015569-vy49r1zd 880 13 females female NNS cord-015569-vy49r1zd 880 14 ; ; : cord-015569-vy49r1zd 880 15 age age NN cord-015569-vy49r1zd 880 16 range range NN cord-015569-vy49r1zd 880 17 : : : cord-015569-vy49r1zd 880 18 21 21 CD cord-015569-vy49r1zd 880 19 - - SYM cord-015569-vy49r1zd 880 20 74 74 CD cord-015569-vy49r1zd 880 21 years year NNS cord-015569-vy49r1zd 880 22 ; ; : cord-015569-vy49r1zd 880 23 mean mean VB cord-015569-vy49r1zd 880 24 age age NN cord-015569-vy49r1zd 880 25 : : : cord-015569-vy49r1zd 880 26 50.9±12.7 50.9±12.7 CD cord-015569-vy49r1zd 880 27 years year NNS cord-015569-vy49r1zd 880 28 ) ) -RRB- cord-015569-vy49r1zd 880 29 with with IN cord-015569-vy49r1zd 880 30 OD OD NNP cord-015569-vy49r1zd 880 31 due due IN cord-015569-vy49r1zd 880 32 to to IN cord-015569-vy49r1zd 880 33 CRS CRS NNP cord-015569-vy49r1zd 880 34 underwent undergo VBD cord-015569-vy49r1zd 880 35 appropriate appropriate JJ cord-015569-vy49r1zd 880 36 surgery surgery NN cord-015569-vy49r1zd 880 37 and and CC cord-015569-vy49r1zd 880 38 postoperative postoperative JJ cord-015569-vy49r1zd 880 39 treatment treatment NN cord-015569-vy49r1zd 880 40 , , , cord-015569-vy49r1zd 880 41 and and CC cord-015569-vy49r1zd 880 42 were be VBD cord-015569-vy49r1zd 880 43 followed follow VBN cord-015569-vy49r1zd 880 44 up up RP cord-015569-vy49r1zd 880 45 for for IN cord-015569-vy49r1zd 880 46 at at RB cord-015569-vy49r1zd 880 47 least least JJS cord-015569-vy49r1zd 880 48 3 3 CD cord-015569-vy49r1zd 880 49 months month NNS cord-015569-vy49r1zd 880 50 . . . cord-015569-vy49r1zd 881 1 A a DT cord-015569-vy49r1zd 881 2 visual visual JJ cord-015569-vy49r1zd 881 3 analog analog NN cord-015569-vy49r1zd 881 4 scale scale NN cord-015569-vy49r1zd 881 5 ( ( -LRB- cord-015569-vy49r1zd 881 6 VAS VAS NNP cord-015569-vy49r1zd 881 7 ) ) -RRB- cord-015569-vy49r1zd 881 8 was be VBD cord-015569-vy49r1zd 881 9 used use VBN cord-015569-vy49r1zd 881 10 to to TO cord-015569-vy49r1zd 881 11 evaluate evaluate VB cord-015569-vy49r1zd 881 12 their -PRON- PRP$ cord-015569-vy49r1zd 881 13 pre pre JJ cord-015569-vy49r1zd 881 14 - - JJ cord-015569-vy49r1zd 881 15 and and CC cord-015569-vy49r1zd 881 16 post post JJ cord-015569-vy49r1zd 881 17 - - JJ cord-015569-vy49r1zd 881 18 treatment treatment JJ cord-015569-vy49r1zd 881 19 symptoms symptom NNS cord-015569-vy49r1zd 881 20 of of IN cord-015569-vy49r1zd 881 21 OD OD NNP cord-015569-vy49r1zd 881 22 . . . cord-015569-vy49r1zd 882 1 [ [ -LRB- cord-015569-vy49r1zd 882 2 Results result NNS cord-015569-vy49r1zd 882 3 and and CC cord-015569-vy49r1zd 882 4 Discussion Discussion NNP cord-015569-vy49r1zd 882 5 ] ] -RRB- cord-015569-vy49r1zd 882 6 Patients patient NNS cord-015569-vy49r1zd 882 7 with with IN cord-015569-vy49r1zd 882 8 an an DT cord-015569-vy49r1zd 882 9 OD OD NNP cord-015569-vy49r1zd 882 10 duration duration NN cord-015569-vy49r1zd 882 11 of of IN cord-015569-vy49r1zd 882 12 ‡5 ‡5 CD cord-015569-vy49r1zd 882 13 years year NNS cord-015569-vy49r1zd 882 14 showed show VBD cord-015569-vy49r1zd 882 15 significantly significantly RB cord-015569-vy49r1zd 882 16 less less JJR cord-015569-vy49r1zd 882 17 improvement improvement NN cord-015569-vy49r1zd 882 18 compared compare VBN cord-015569-vy49r1zd 882 19 with with IN cord-015569-vy49r1zd 882 20 an an DT cord-015569-vy49r1zd 882 21 OD OD NNP cord-015569-vy49r1zd 882 22 duration duration NN cord-015569-vy49r1zd 882 23 of of IN cord-015569-vy49r1zd 882 24 < < $ cord-015569-vy49r1zd 882 25 5 5 CD cord-015569-vy49r1zd 882 26 years year NNS cord-015569-vy49r1zd 882 27 . . . cord-015569-vy49r1zd 883 1 The the DT cord-015569-vy49r1zd 883 2 OD OD NNP cord-015569-vy49r1zd 883 3 duration duration NN cord-015569-vy49r1zd 883 4 and and CC cord-015569-vy49r1zd 883 5 the the DT cord-015569-vy49r1zd 883 6 post post JJ cord-015569-vy49r1zd 883 7 treatment treatment NN cord-015569-vy49r1zd 883 8 VAS VAS NNP cord-015569-vy49r1zd 883 9 showed show VBD cord-015569-vy49r1zd 883 10 a a DT cord-015569-vy49r1zd 883 11 significant significant JJ cord-015569-vy49r1zd 883 12 negative negative JJ cord-015569-vy49r1zd 883 13 correlation correlation NN cord-015569-vy49r1zd 883 14 ( ( -LRB- cord-015569-vy49r1zd 883 15 r r NN cord-015569-vy49r1zd 883 16 s s NN cord-015569-vy49r1zd 883 17 = = NN cord-015569-vy49r1zd 883 18 À.399 À.399 NNP cord-015569-vy49r1zd 883 19 , , , cord-015569-vy49r1zd 883 20 n=113 n=113 NNP cord-015569-vy49r1zd 883 21 ) ) -RRB- cord-015569-vy49r1zd 883 22 . . . cord-015569-vy49r1zd 884 1 It -PRON- PRP cord-015569-vy49r1zd 884 2 was be VBD cord-015569-vy49r1zd 884 3 particularly particularly RB cord-015569-vy49r1zd 884 4 strong strong JJ cord-015569-vy49r1zd 884 5 in in IN cord-015569-vy49r1zd 884 6 male male JJ cord-015569-vy49r1zd 884 7 patients patient NNS cord-015569-vy49r1zd 884 8 aged age VBN cord-015569-vy49r1zd 884 9 ‡60 ‡60 NNP cord-015569-vy49r1zd 884 10 years year NNS cord-015569-vy49r1zd 885 1 ( ( -LRB- cord-015569-vy49r1zd 885 2 r r NNP cord-015569-vy49r1zd 885 3 s s NN cord-015569-vy49r1zd 885 4 = = SYM cord-015569-vy49r1zd 885 5 À.632 à.632 CD cord-015569-vy49r1zd 885 6 , , , cord-015569-vy49r1zd 885 7 n=27 n=27 NNP cord-015569-vy49r1zd 885 8 ) ) -RRB- cord-015569-vy49r1zd 885 9 , , , cord-015569-vy49r1zd 885 10 and and CC cord-015569-vy49r1zd 886 1 in in IN cord-015569-vy49r1zd 886 2 the the DT cord-015569-vy49r1zd 886 3 aspirin aspirin NN cord-015569-vy49r1zd 886 4 - - HYPH cord-015569-vy49r1zd 886 5 intolerant intolerant JJ cord-015569-vy49r1zd 886 6 asthma asthma NN cord-015569-vy49r1zd 886 7 ( ( -LRB- cord-015569-vy49r1zd 886 8 r r NNP cord-015569-vy49r1zd 886 9 s s NN cord-015569-vy49r1zd 886 10 = = SYM cord-015569-vy49r1zd 886 11 À.624 À.624 NNP cord-015569-vy49r1zd 886 12 , , , cord-015569-vy49r1zd 886 13 n=11 n=11 NNP cord-015569-vy49r1zd 886 14 ) ) -RRB- cord-015569-vy49r1zd 886 15 , , , cord-015569-vy49r1zd 886 16 peripheral peripheral JJ cord-015569-vy49r1zd 886 17 eosinophil eosinophil JJ cord-015569-vy49r1zd 886 18 count count NN cord-015569-vy49r1zd 886 19 of of IN cord-015569-vy49r1zd 886 20 ‡800 ‡800 NNP cord-015569-vy49r1zd 886 21 / / SYM cord-015569-vy49r1zd 886 22 microL microL NNP cord-015569-vy49r1zd 887 1 ( ( -LRB- cord-015569-vy49r1zd 887 2 r r NNP cord-015569-vy49r1zd 887 3 s s NN cord-015569-vy49r1zd 887 4 = = NN cord-015569-vy49r1zd 887 5 À.528 À.528 NNP cord-015569-vy49r1zd 887 6 , , , cord-015569-vy49r1zd 887 7 n=17 n=17 NNP cord-015569-vy49r1zd 887 8 ) ) -RRB- cord-015569-vy49r1zd 887 9 and and CC cord-015569-vy49r1zd 887 10 current current JJ cord-015569-vy49r1zd 887 11 smoking smoking NN cord-015569-vy49r1zd 888 1 ( ( -LRB- cord-015569-vy49r1zd 888 2 r r NNP cord-015569-vy49r1zd 888 3 s s NNP cord-015569-vy49r1zd 889 1 = = SYM cord-015569-vy49r1zd 889 2 À.731 à.731 PRP cord-015569-vy49r1zd 889 3 , , , cord-015569-vy49r1zd 889 4 n=11 n=11 NNP cord-015569-vy49r1zd 889 5 ) ) -RRB- cord-015569-vy49r1zd 889 6 subgroups subgroup NNS cord-015569-vy49r1zd 889 7 . . . cord-015569-vy49r1zd 890 1 Multiple multiple JJ cord-015569-vy49r1zd 890 2 logistic logistic JJ cord-015569-vy49r1zd 890 3 regression regression NN cord-015569-vy49r1zd 890 4 analysis analysis NN cord-015569-vy49r1zd 890 5 of of IN cord-015569-vy49r1zd 890 6 19 19 CD cord-015569-vy49r1zd 890 7 patients patient NNS cord-015569-vy49r1zd 890 8 with with IN cord-015569-vy49r1zd 890 9 severe severe JJ cord-015569-vy49r1zd 890 10 OD od NN cord-015569-vy49r1zd 890 11 even even RB cord-015569-vy49r1zd 890 12 after after IN cord-015569-vy49r1zd 890 13 appropriate appropriate JJ cord-015569-vy49r1zd 890 14 treatment treatment NN cord-015569-vy49r1zd 890 15 identified identify VBD cord-015569-vy49r1zd 890 16 the the DT cord-015569-vy49r1zd 890 17 following follow VBG cord-015569-vy49r1zd 890 18 as as IN cord-015569-vy49r1zd 890 19 poor poor JJ cord-015569-vy49r1zd 890 20 prognostic prognostic JJ cord-015569-vy49r1zd 890 21 factors factor NNS cord-015569-vy49r1zd 890 22 : : : cord-015569-vy49r1zd 890 23 1 1 LS cord-015569-vy49r1zd 890 24 ) ) -RRB- cord-015569-vy49r1zd 891 1 male male JJ cord-015569-vy49r1zd 891 2 gender gender NN cord-015569-vy49r1zd 891 3 ( ( -LRB- cord-015569-vy49r1zd 891 4 OR=18.996 OR=18.996 NNP cord-015569-vy49r1zd 891 5 ) ) -RRB- cord-015569-vy49r1zd 892 1 , , , cord-015569-vy49r1zd 892 2 2 2 LS cord-015569-vy49r1zd 892 3 ) ) -RRB- cord-015569-vy49r1zd 892 4 OD od NN cord-015569-vy49r1zd 892 5 duration duration NN cord-015569-vy49r1zd 892 6 ‡5 ‡5 CD cord-015569-vy49r1zd 892 7 years year NNS cord-015569-vy49r1zd 892 8 ( ( -LRB- cord-015569-vy49r1zd 892 9 10.023 10.023 CD cord-015569-vy49r1zd 892 10 ) ) -RRB- cord-015569-vy49r1zd 892 11 , , . cord-015569-vy49r1zd 893 1 3 3 LS cord-015569-vy49r1zd 893 2 ) ) -RRB- cord-015569-vy49r1zd 893 3 age age NN cord-015569-vy49r1zd 893 4 ‡60 ‡60 NN cord-015569-vy49r1zd 893 5 years year NNS cord-015569-vy49r1zd 893 6 ( ( -LRB- cord-015569-vy49r1zd 893 7 9.349 9.349 CD cord-015569-vy49r1zd 893 8 ) ) -RRB- cord-015569-vy49r1zd 893 9 and and CC cord-015569-vy49r1zd 893 10 4 4 LS cord-015569-vy49r1zd 893 11 ) ) -RRB- cord-015569-vy49r1zd 893 12 peripheral peripheral JJ cord-015569-vy49r1zd 893 13 eosinophil eosinophil JJ cord-015569-vy49r1zd 893 14 count count NN cord-015569-vy49r1zd 893 15 of of IN cord-015569-vy49r1zd 893 16 ‡800microl ‡800microl NNP cord-015569-vy49r1zd 893 17 ( ( -LRB- cord-015569-vy49r1zd 893 18 8.234 8.234 CD cord-015569-vy49r1zd 893 19 ) ) -RRB- cord-015569-vy49r1zd 893 20 ( ( -LRB- cord-015569-vy49r1zd 893 21 predictive predictive JJ cord-015569-vy49r1zd 893 22 rate rate NN cord-015569-vy49r1zd 893 23 : : : cord-015569-vy49r1zd 893 24 89.4 89.4 CD cord-015569-vy49r1zd 893 25 % % NN cord-015569-vy49r1zd 893 26 ) ) -RRB- cord-015569-vy49r1zd 893 27 . . . cord-015569-vy49r1zd 894 1 These these DT cord-015569-vy49r1zd 894 2 results result NNS cord-015569-vy49r1zd 894 3 indicate indicate VBP cord-015569-vy49r1zd 894 4 that that IN cord-015569-vy49r1zd 894 5 the the DT cord-015569-vy49r1zd 894 6 prognosis prognosis NN cord-015569-vy49r1zd 894 7 of of IN cord-015569-vy49r1zd 894 8 OD OD NNP cord-015569-vy49r1zd 894 9 due due IN cord-015569-vy49r1zd 894 10 to to IN cord-015569-vy49r1zd 894 11 CRS CRS NNP cord-015569-vy49r1zd 894 12 becomes become VBZ cord-015569-vy49r1zd 894 13 poorer poor JJR cord-015569-vy49r1zd 894 14 as as IN cord-015569-vy49r1zd 894 15 the the DT cord-015569-vy49r1zd 894 16 duration duration NN cord-015569-vy49r1zd 894 17 of of IN cord-015569-vy49r1zd 894 18 the the DT cord-015569-vy49r1zd 894 19 disease disease NN cord-015569-vy49r1zd 894 20 becomes become VBZ cord-015569-vy49r1zd 894 21 longer long RBR cord-015569-vy49r1zd 894 22 . . . cord-015569-vy49r1zd 895 1 In in IN cord-015569-vy49r1zd 895 2 particular particular JJ cord-015569-vy49r1zd 895 3 , , , cord-015569-vy49r1zd 895 4 patients patient NNS cord-015569-vy49r1zd 895 5 who who WP cord-015569-vy49r1zd 895 6 have have VBP cord-015569-vy49r1zd 895 7 these these DT cord-015569-vy49r1zd 895 8 risk risk NN cord-015569-vy49r1zd 895 9 factors factor NNS cord-015569-vy49r1zd 895 10 should should MD cord-015569-vy49r1zd 895 11 be be VB cord-015569-vy49r1zd 895 12 started start VBN cord-015569-vy49r1zd 895 13 on on IN cord-015569-vy49r1zd 895 14 treatment treatment NN cord-015569-vy49r1zd 895 15 as as RB cord-015569-vy49r1zd 895 16 soon soon RB cord-015569-vy49r1zd 895 17 as as IN cord-015569-vy49r1zd 895 18 possible possible JJ cord-015569-vy49r1zd 895 19 and and CC cord-015569-vy49r1zd 895 20 should should MD cord-015569-vy49r1zd 895 21 be be VB cord-015569-vy49r1zd 895 22 advised advise VBN cord-015569-vy49r1zd 895 23 to to TO cord-015569-vy49r1zd 895 24 quit quit VB cord-015569-vy49r1zd 895 25 smoking smoking NN cord-015569-vy49r1zd 895 26 . . . cord-015569-vy49r1zd 896 1 Motohiko Motohiko NNP cord-015569-vy49r1zd 896 2 Suzuki Suzuki NNP cord-015569-vy49r1zd 896 3 , , , cord-015569-vy49r1zd 896 4 Yoshihisa Yoshihisa NNP cord-015569-vy49r1zd 896 5 Nakamura Nakamura NNP cord-015569-vy49r1zd 896 6 , , , cord-015569-vy49r1zd 896 7 Hiroshi Hiroshi NNP cord-015569-vy49r1zd 896 8 Kawaguchi Kawaguchi NNP cord-015569-vy49r1zd 896 9 and and CC cord-015569-vy49r1zd 896 10 Shingo Shingo NNP cord-015569-vy49r1zd 896 11 Murakami Murakami NNP cord-015569-vy49r1zd 896 12 Causative causative JJ cord-015569-vy49r1zd 896 13 viruses virus NNS cord-015569-vy49r1zd 896 14 of of IN cord-015569-vy49r1zd 896 15 postviral postviral JJ cord-015569-vy49r1zd 896 16 olfactory olfactory JJ cord-015569-vy49r1zd 896 17 dysfunction dysfunction NN cord-015569-vy49r1zd 896 18 have have VBP cord-015569-vy49r1zd 896 19 not not RB cord-015569-vy49r1zd 896 20 yet yet RB cord-015569-vy49r1zd 896 21 been be VBN cord-015569-vy49r1zd 896 22 identified identify VBN cord-015569-vy49r1zd 896 23 . . . cord-015569-vy49r1zd 897 1 We -PRON- PRP cord-015569-vy49r1zd 897 2 investigated investigate VBD cord-015569-vy49r1zd 897 3 causative causative JJ cord-015569-vy49r1zd 897 4 viruses virus NNS cord-015569-vy49r1zd 897 5 in in IN cord-015569-vy49r1zd 897 6 patients patient NNS cord-015569-vy49r1zd 897 7 with with IN cord-015569-vy49r1zd 897 8 postviral postviral JJ cord-015569-vy49r1zd 897 9 olfactory olfactory JJ cord-015569-vy49r1zd 897 10 dysfunction dysfunction NN cord-015569-vy49r1zd 897 11 . . . cord-015569-vy49r1zd 898 1 We -PRON- PRP cord-015569-vy49r1zd 898 2 examined examine VBD cord-015569-vy49r1zd 898 3 the the DT cord-015569-vy49r1zd 898 4 presence presence NN cord-015569-vy49r1zd 898 5 of of IN cord-015569-vy49r1zd 898 6 viruses virus NNS cord-015569-vy49r1zd 898 7 in in IN cord-015569-vy49r1zd 898 8 nasal nasal NN cord-015569-vy49r1zd 898 9 discharge discharge NN cord-015569-vy49r1zd 898 10 and and CC cord-015569-vy49r1zd 898 11 examined examine VBD cord-015569-vy49r1zd 898 12 the the DT cord-015569-vy49r1zd 898 13 time time NN cord-015569-vy49r1zd 898 14 course course NN cord-015569-vy49r1zd 898 15 , , , cord-015569-vy49r1zd 898 16 with with IN cord-015569-vy49r1zd 898 17 regard regard NN cord-015569-vy49r1zd 898 18 to to IN cord-015569-vy49r1zd 898 19 changes change NNS cord-015569-vy49r1zd 898 20 in in IN cord-015569-vy49r1zd 898 21 olfactory olfactory JJ cord-015569-vy49r1zd 898 22 dysfunction dysfunction NN cord-015569-vy49r1zd 898 23 and and CC cord-015569-vy49r1zd 898 24 nasal nasal JJ cord-015569-vy49r1zd 898 25 obstruction obstruction NN cord-015569-vy49r1zd 898 26 in in IN cord-015569-vy49r1zd 898 27 24 24 CD cord-015569-vy49r1zd 898 28 patients patient NNS cord-015569-vy49r1zd 898 29 with with IN cord-015569-vy49r1zd 898 30 postviral postviral JJ cord-015569-vy49r1zd 898 31 olfactory olfactory JJ cord-015569-vy49r1zd 898 32 dysfunction dysfunction NN cord-015569-vy49r1zd 898 33 , , , cord-015569-vy49r1zd 898 34 using use VBG cord-015569-vy49r1zd 898 35 questionnaires questionnaire NNS cord-015569-vy49r1zd 898 36 , , , cord-015569-vy49r1zd 898 37 acoustic acoustic JJ cord-015569-vy49r1zd 898 38 rhinometry rhinometry NN cord-015569-vy49r1zd 898 39 , , , cord-015569-vy49r1zd 898 40 and and CC cord-015569-vy49r1zd 898 41 olfactory olfactory JJ cord-015569-vy49r1zd 898 42 tests test NNS cord-015569-vy49r1zd 898 43 . . . cord-015569-vy49r1zd 899 1 Nasal nasal NN cord-015569-vy49r1zd 899 2 discharge discharge NN cord-015569-vy49r1zd 899 3 was be VBD cord-015569-vy49r1zd 899 4 collected collect VBN cord-015569-vy49r1zd 899 5 from from IN cord-015569-vy49r1zd 899 6 patients patient NNS cord-015569-vy49r1zd 899 7 with with IN cord-015569-vy49r1zd 899 8 postviral postviral JJ cord-015569-vy49r1zd 899 9 olfactory olfactory JJ cord-015569-vy49r1zd 899 10 dysfunction dysfunction NN cord-015569-vy49r1zd 899 11 . . . cord-015569-vy49r1zd 900 1 Rhinoviruses Rhinoviruses NNP cord-015569-vy49r1zd 900 2 were be VBD cord-015569-vy49r1zd 900 3 detected detect VBN cord-015569-vy49r1zd 900 4 in in IN cord-015569-vy49r1zd 900 5 10 10 CD cord-015569-vy49r1zd 900 6 patients patient NNS cord-015569-vy49r1zd 900 7 . . . cord-015569-vy49r1zd 901 1 Viral viral JJ cord-015569-vy49r1zd 901 2 serotypes serotype NNS cord-015569-vy49r1zd 901 3 were be VBD cord-015569-vy49r1zd 901 4 identified identify VBN cord-015569-vy49r1zd 901 5 by by IN cord-015569-vy49r1zd 901 6 nucleotide nucleotide JJ cord-015569-vy49r1zd 901 7 sequences sequence NNS cord-015569-vy49r1zd 901 8 to to TO cord-015569-vy49r1zd 901 9 be be VB cord-015569-vy49r1zd 901 10 human human JJ cord-015569-vy49r1zd 901 11 rhinovirus-40 rhinovirus-40 NN cord-015569-vy49r1zd 901 12 , , , cord-015569-vy49r1zd 901 13 human human JJ cord-015569-vy49r1zd 901 14 rhinovirus-75 rhinovirus-75 CD cord-015569-vy49r1zd 901 15 , , , cord-015569-vy49r1zd 901 16 human human NN cord-015569-vy49r1zd 901 17 rhinovirus-78 rhinovirus-78 NN cord-015569-vy49r1zd 901 18 , , , cord-015569-vy49r1zd 901 19 and and CC cord-015569-vy49r1zd 901 20 human human JJ cord-015569-vy49r1zd 901 21 rhinovirus-80 rhinovirus-80 CD cord-015569-vy49r1zd 901 22 . . . cord-015569-vy49r1zd 902 1 One one CD cord-015569-vy49r1zd 902 2 of of IN cord-015569-vy49r1zd 902 3 the the DT cord-015569-vy49r1zd 902 4 four four CD cord-015569-vy49r1zd 902 5 patients patient NNS cord-015569-vy49r1zd 902 6 complained complain VBN cord-015569-vy49r1zd 902 7 of of IN cord-015569-vy49r1zd 902 8 dysosmia dysosmia NNP cord-015569-vy49r1zd 902 9 , , , cord-015569-vy49r1zd 902 10 whereas whereas IN cord-015569-vy49r1zd 902 11 another another DT cord-015569-vy49r1zd 902 12 complained complain VBD cord-015569-vy49r1zd 902 13 of of IN cord-015569-vy49r1zd 902 14 anosmia anosmia NN cord-015569-vy49r1zd 902 15 . . . cord-015569-vy49r1zd 903 1 Results result NNS cord-015569-vy49r1zd 903 2 of of IN cord-015569-vy49r1zd 903 3 acoustic acoustic JJ cord-015569-vy49r1zd 903 4 rhinometry rhinometry NN cord-015569-vy49r1zd 903 5 significantly significantly RB cord-015569-vy49r1zd 903 6 improved improve VBD cord-015569-vy49r1zd 903 7 in in IN cord-015569-vy49r1zd 903 8 the the DT cord-015569-vy49r1zd 903 9 four four CD cord-015569-vy49r1zd 903 10 patients patient NNS cord-015569-vy49r1zd 903 11 , , , cord-015569-vy49r1zd 903 12 although although IN cord-015569-vy49r1zd 903 13 olfactory olfactory JJ cord-015569-vy49r1zd 903 14 testing testing NN cord-015569-vy49r1zd 903 15 did do VBD cord-015569-vy49r1zd 903 16 not not RB cord-015569-vy49r1zd 903 17 show show VB cord-015569-vy49r1zd 903 18 significant significant JJ cord-015569-vy49r1zd 903 19 improvement improvement NN cord-015569-vy49r1zd 903 20 . . . cord-015569-vy49r1zd 904 1 Two two CD cord-015569-vy49r1zd 904 2 of of IN cord-015569-vy49r1zd 904 3 the the DT cord-015569-vy49r1zd 904 4 four four CD cord-015569-vy49r1zd 904 5 patients patient NNS cord-015569-vy49r1zd 904 6 complained complain VBN cord-015569-vy49r1zd 904 7 of of IN cord-015569-vy49r1zd 904 8 olfactory olfactory JJ cord-015569-vy49r1zd 904 9 dysfunction dysfunction NN cord-015569-vy49r1zd 904 10 even even RB cord-015569-vy49r1zd 904 11 6 6 CD cord-015569-vy49r1zd 904 12 months month NNS cord-015569-vy49r1zd 904 13 after after IN cord-015569-vy49r1zd 904 14 the the DT cord-015569-vy49r1zd 904 15 first first JJ cord-015569-vy49r1zd 904 16 visit visit NN cord-015569-vy49r1zd 904 17 . . . cord-015569-vy49r1zd 905 1 Coronavirus Coronavirus NNP cord-015569-vy49r1zd 905 2 and and CC cord-015569-vy49r1zd 905 3 parainfluenza parainfluenza NNP cord-015569-vy49r1zd 905 4 virus virus NN cord-015569-vy49r1zd 905 5 were be VBD cord-015569-vy49r1zd 905 6 detected detect VBN cord-015569-vy49r1zd 905 7 in in IN cord-015569-vy49r1zd 905 8 one one CD cord-015569-vy49r1zd 905 9 patient patient NN cord-015569-vy49r1zd 905 10 each each DT cord-015569-vy49r1zd 905 11 , , , cord-015569-vy49r1zd 905 12 and and CC cord-015569-vy49r1zd 905 13 Epstein Epstein NNP cord-015569-vy49r1zd 905 14 - - HYPH cord-015569-vy49r1zd 905 15 Barr Barr NNP cord-015569-vy49r1zd 905 16 viruses virus NNS cord-015569-vy49r1zd 905 17 were be VBD cord-015569-vy49r1zd 905 18 detected detect VBN cord-015569-vy49r1zd 905 19 in in IN cord-015569-vy49r1zd 905 20 three three CD cord-015569-vy49r1zd 905 21 patients patient NNS cord-015569-vy49r1zd 905 22 . . . cord-015569-vy49r1zd 906 1 The the DT cord-015569-vy49r1zd 906 2 present present JJ cord-015569-vy49r1zd 906 3 study study NN cord-015569-vy49r1zd 906 4 detected detect VBD cord-015569-vy49r1zd 906 5 rhinovirus rhinovirus NN cord-015569-vy49r1zd 906 6 , , , cord-015569-vy49r1zd 906 7 coronavirus coronavirus NN cord-015569-vy49r1zd 906 8 , , , cord-015569-vy49r1zd 906 9 parainfluenza parainfluenza NNP cord-015569-vy49r1zd 906 10 virus virus NNP cord-015569-vy49r1zd 906 11 , , , cord-015569-vy49r1zd 906 12 and and CC cord-015569-vy49r1zd 906 13 Epstein Epstein NNP cord-015569-vy49r1zd 906 14 - - HYPH cord-015569-vy49r1zd 906 15 Barr Barr NNP cord-015569-vy49r1zd 906 16 virus virus NN cord-015569-vy49r1zd 906 17 in in IN cord-015569-vy49r1zd 906 18 nasal nasal JJ cord-015569-vy49r1zd 906 19 discharge discharge NN cord-015569-vy49r1zd 906 20 of of IN cord-015569-vy49r1zd 906 21 patients patient NNS cord-015569-vy49r1zd 906 22 with with IN cord-015569-vy49r1zd 906 23 postviral postviral NNP cord-015569-vy49r1zd 906 24 olfactory olfactory JJ cord-015569-vy49r1zd 906 25 dysfunction dysfunction NN cord-015569-vy49r1zd 906 26 . . . cord-015569-vy49r1zd 907 1 Furthermore furthermore RB cord-015569-vy49r1zd 907 2 , , , cord-015569-vy49r1zd 907 3 this this DT cord-015569-vy49r1zd 907 4 study study NN cord-015569-vy49r1zd 907 5 suggests suggest VBZ cord-015569-vy49r1zd 907 6 that that IN cord-015569-vy49r1zd 907 7 rhinoviruses rhinovirus NNS cord-015569-vy49r1zd 907 8 cause cause VBP cord-015569-vy49r1zd 907 9 olfactory olfactory JJ cord-015569-vy49r1zd 907 10 dysfunction dysfunction NN cord-015569-vy49r1zd 907 11 through through IN cord-015569-vy49r1zd 907 12 mechanisms mechanism NNS cord-015569-vy49r1zd 907 13 other other JJ cord-015569-vy49r1zd 907 14 than than IN cord-015569-vy49r1zd 907 15 nasal nasal JJ cord-015569-vy49r1zd 907 16 obstruction obstruction NN cord-015569-vy49r1zd 907 17 . . . cord-015569-vy49r1zd 908 1 In in IN cord-015569-vy49r1zd 908 2 this this DT cord-015569-vy49r1zd 908 3 study study NN cord-015569-vy49r1zd 908 4 , , , cord-015569-vy49r1zd 908 5 we -PRON- PRP cord-015569-vy49r1zd 908 6 evaluated evaluate VBD cord-015569-vy49r1zd 908 7 10 10 CD cord-015569-vy49r1zd 908 8 patients patient NNS cord-015569-vy49r1zd 908 9 with with IN cord-015569-vy49r1zd 908 10 olfactory olfactory JJ cord-015569-vy49r1zd 908 11 dysfunction dysfunction NN cord-015569-vy49r1zd 908 12 induced induce VBN cord-015569-vy49r1zd 908 13 by by IN cord-015569-vy49r1zd 908 14 central central JJ cord-015569-vy49r1zd 908 15 nervous nervous JJ cord-015569-vy49r1zd 908 16 damage damage NN cord-015569-vy49r1zd 908 17 . . . cord-015569-vy49r1zd 909 1 Six six CD cord-015569-vy49r1zd 909 2 of of IN cord-015569-vy49r1zd 909 3 10 10 CD cord-015569-vy49r1zd 909 4 patients patient NNS cord-015569-vy49r1zd 909 5 developed develop VBN cord-015569-vy49r1zd 909 6 hyposmia hyposmia NN cord-015569-vy49r1zd 909 7 after after IN cord-015569-vy49r1zd 909 8 head head NN cord-015569-vy49r1zd 909 9 trauma trauma NN cord-015569-vy49r1zd 909 10 , , , cord-015569-vy49r1zd 909 11 2 2 CD cord-015569-vy49r1zd 909 12 patients patient NNS cord-015569-vy49r1zd 909 13 by by IN cord-015569-vy49r1zd 909 14 brain brain NN cord-015569-vy49r1zd 909 15 tumor tumor NN cord-015569-vy49r1zd 909 16 , , , cord-015569-vy49r1zd 909 17 one one CD cord-015569-vy49r1zd 909 18 patient patient NN cord-015569-vy49r1zd 909 19 after after IN cord-015569-vy49r1zd 909 20 subarachnoid subarachnoid NN cord-015569-vy49r1zd 909 21 bleeding bleed VBG cord-015569-vy49r1zd 909 22 and and CC cord-015569-vy49r1zd 909 23 one one CD cord-015569-vy49r1zd 909 24 patient patient NN cord-015569-vy49r1zd 909 25 by by IN cord-015569-vy49r1zd 909 26 encephalitis encephalitis RB cord-015569-vy49r1zd 909 27 . . . cord-015569-vy49r1zd 910 1 Five five CD cord-015569-vy49r1zd 910 2 of of IN cord-015569-vy49r1zd 910 3 10 10 CD cord-015569-vy49r1zd 910 4 patients patient NNS cord-015569-vy49r1zd 910 5 did do VBD cord-015569-vy49r1zd 910 6 not not RB cord-015569-vy49r1zd 910 7 sense sense VB cord-015569-vy49r1zd 910 8 any any DT cord-015569-vy49r1zd 910 9 smell smell NN cord-015569-vy49r1zd 910 10 by by IN cord-015569-vy49r1zd 910 11 venous venous JJ cord-015569-vy49r1zd 910 12 injection injection NN cord-015569-vy49r1zd 910 13 of of IN cord-015569-vy49r1zd 910 14 prosultiamine prosultiamine NN cord-015569-vy49r1zd 910 15 . . . cord-015569-vy49r1zd 911 1 Psychophysical psychophysical JJ cord-015569-vy49r1zd 911 2 evaluation evaluation NN cord-015569-vy49r1zd 911 3 of of IN cord-015569-vy49r1zd 911 4 olfactory olfactory JJ cord-015569-vy49r1zd 911 5 function function NN cord-015569-vy49r1zd 911 6 was be VBD cord-015569-vy49r1zd 911 7 performed perform VBN cord-015569-vy49r1zd 911 8 by by IN cord-015569-vy49r1zd 911 9 T&T T&T NNP cord-015569-vy49r1zd 911 10 olfactometry olfactometry NN cord-015569-vy49r1zd 911 11 , , , cord-015569-vy49r1zd 911 12 and and CC cord-015569-vy49r1zd 911 13 the the DT cord-015569-vy49r1zd 911 14 average average JJ cord-015569-vy49r1zd 911 15 threshold threshold NN cord-015569-vy49r1zd 911 16 score score NN cord-015569-vy49r1zd 911 17 of of IN cord-015569-vy49r1zd 911 18 recognition recognition NN cord-015569-vy49r1zd 911 19 was be VBD cord-015569-vy49r1zd 911 20 5.2 5.2 CD cord-015569-vy49r1zd 911 21 ( ( -LRB- cord-015569-vy49r1zd 911 22 severe severe JJ cord-015569-vy49r1zd 911 23 hyposmia hyposmia NN cord-015569-vy49r1zd 911 24 ) ) -RRB- cord-015569-vy49r1zd 911 25 . . . cord-015569-vy49r1zd 912 1 Eight eight CD cord-015569-vy49r1zd 912 2 patients patient NNS cord-015569-vy49r1zd 912 3 got get VBD cord-015569-vy49r1zd 912 4 MRI MRI NNP cord-015569-vy49r1zd 912 5 brain brain NN cord-015569-vy49r1zd 912 6 scans scan NNS cord-015569-vy49r1zd 912 7 and and CC cord-015569-vy49r1zd 912 8 each each DT cord-015569-vy49r1zd 912 9 of of IN cord-015569-vy49r1zd 912 10 them -PRON- PRP cord-015569-vy49r1zd 912 11 had have VBD cord-015569-vy49r1zd 912 12 one one CD cord-015569-vy49r1zd 912 13 or or CC cord-015569-vy49r1zd 912 14 more more JJR cord-015569-vy49r1zd 912 15 intracranial intracranial JJ cord-015569-vy49r1zd 912 16 lesions lesion NNS cord-015569-vy49r1zd 912 17 . . . cord-015569-vy49r1zd 913 1 Frontal frontal JJ cord-015569-vy49r1zd 913 2 lobe lobe NN cord-015569-vy49r1zd 913 3 abnormalities abnormality NNS cord-015569-vy49r1zd 913 4 were be VBD cord-015569-vy49r1zd 913 5 seen see VBN cord-015569-vy49r1zd 913 6 in in IN cord-015569-vy49r1zd 913 7 7 7 CD cord-015569-vy49r1zd 913 8 of of IN cord-015569-vy49r1zd 913 9 8 8 CD cord-015569-vy49r1zd 913 10 patients patient NNS cord-015569-vy49r1zd 913 11 . . . cord-015569-vy49r1zd 914 1 Intracranial intracranial JJ cord-015569-vy49r1zd 914 2 lesions lesion NNS cord-015569-vy49r1zd 914 3 were be VBD cord-015569-vy49r1zd 914 4 also also RB cord-015569-vy49r1zd 914 5 observed observe VBN cord-015569-vy49r1zd 914 6 in in IN cord-015569-vy49r1zd 914 7 3 3 CD cord-015569-vy49r1zd 914 8 temporal temporal JJ cord-015569-vy49r1zd 914 9 lobes lobe NNS cord-015569-vy49r1zd 914 10 and and CC cord-015569-vy49r1zd 914 11 one one CD cord-015569-vy49r1zd 914 12 parietal parietal JJ cord-015569-vy49r1zd 914 13 lobe lobe NN cord-015569-vy49r1zd 914 14 and and CC cord-015569-vy49r1zd 914 15 one one CD cord-015569-vy49r1zd 914 16 occipital occipital JJ cord-015569-vy49r1zd 914 17 lobe lobe NN cord-015569-vy49r1zd 914 18 . . . cord-015569-vy49r1zd 915 1 These these DT cord-015569-vy49r1zd 915 2 MRI MRI NNP cord-015569-vy49r1zd 915 3 findings finding NNS cord-015569-vy49r1zd 915 4 suggested suggest VBD cord-015569-vy49r1zd 915 5 most most JJS cord-015569-vy49r1zd 915 6 of of IN cord-015569-vy49r1zd 915 7 the the DT cord-015569-vy49r1zd 915 8 olfactory olfactory JJ cord-015569-vy49r1zd 915 9 disorders disorder NNS cord-015569-vy49r1zd 915 10 were be VBD cord-015569-vy49r1zd 915 11 come come VBN cord-015569-vy49r1zd 915 12 from from IN cord-015569-vy49r1zd 915 13 damage damage NN cord-015569-vy49r1zd 915 14 of of IN cord-015569-vy49r1zd 915 15 orbitofrontal orbitofrontal JJ cord-015569-vy49r1zd 915 16 cortex cortex NN cord-015569-vy49r1zd 915 17 in in IN cord-015569-vy49r1zd 915 18 frontal frontal JJ cord-015569-vy49r1zd 915 19 lobe lobe NN cord-015569-vy49r1zd 915 20 , , , cord-015569-vy49r1zd 915 21 which which WDT cord-015569-vy49r1zd 915 22 is be VBZ cord-015569-vy49r1zd 915 23 thought think VBN cord-015569-vy49r1zd 915 24 to to TO cord-015569-vy49r1zd 915 25 be be VB cord-015569-vy49r1zd 915 26 the the DT cord-015569-vy49r1zd 915 27 olfactory olfactory JJ cord-015569-vy49r1zd 915 28 center center NN cord-015569-vy49r1zd 915 29 . . . cord-015569-vy49r1zd 916 1 On on IN cord-015569-vy49r1zd 916 2 the the DT cord-015569-vy49r1zd 916 3 other other JJ cord-015569-vy49r1zd 916 4 hand hand NN cord-015569-vy49r1zd 916 5 , , , cord-015569-vy49r1zd 916 6 8 8 CD cord-015569-vy49r1zd 916 7 out out IN cord-015569-vy49r1zd 916 8 of of IN cord-015569-vy49r1zd 916 9 10 10 CD cord-015569-vy49r1zd 916 10 patients patient NNS cord-015569-vy49r1zd 916 11 developed develop VBD cord-015569-vy49r1zd 916 12 taste taste NN cord-015569-vy49r1zd 916 13 disorder disorder NN cord-015569-vy49r1zd 916 14 , , , cord-015569-vy49r1zd 916 15 despite despite IN cord-015569-vy49r1zd 916 16 no no DT cord-015569-vy49r1zd 916 17 pathogenic pathogenic JJ cord-015569-vy49r1zd 916 18 lesion lesion NN cord-015569-vy49r1zd 916 19 was be VBD cord-015569-vy49r1zd 916 20 found find VBN cord-015569-vy49r1zd 916 21 in in IN cord-015569-vy49r1zd 916 22 medullary medullary JJ cord-015569-vy49r1zd 916 23 , , , cord-015569-vy49r1zd 916 24 thalamus thalamus NN cord-015569-vy49r1zd 916 25 and and CC cord-015569-vy49r1zd 916 26 insula insula NNP cord-015569-vy49r1zd 916 27 , , , cord-015569-vy49r1zd 916 28 which which WDT cord-015569-vy49r1zd 916 29 are be VBP cord-015569-vy49r1zd 916 30 thought think VBN cord-015569-vy49r1zd 916 31 to to TO cord-015569-vy49r1zd 916 32 be be VB cord-015569-vy49r1zd 916 33 the the DT cord-015569-vy49r1zd 916 34 central central JJ cord-015569-vy49r1zd 916 35 pathway pathway NN cord-015569-vy49r1zd 916 36 of of IN cord-015569-vy49r1zd 916 37 taste taste NN cord-015569-vy49r1zd 916 38 and and CC cord-015569-vy49r1zd 916 39 taste taste VBP cord-015569-vy49r1zd 916 40 cortex cortex NN cord-015569-vy49r1zd 916 41 . . . cord-015569-vy49r1zd 917 1 Currently currently RB cord-015569-vy49r1zd 917 2 , , , cord-015569-vy49r1zd 917 3 we -PRON- PRP cord-015569-vy49r1zd 917 4 have have VBP cord-015569-vy49r1zd 917 5 yet yet RB cord-015569-vy49r1zd 917 6 to to TO cord-015569-vy49r1zd 917 7 establish establish VB cord-015569-vy49r1zd 917 8 effective effective JJ cord-015569-vy49r1zd 917 9 treatment treatment NN cord-015569-vy49r1zd 917 10 of of IN cord-015569-vy49r1zd 917 11 olfactory olfactory JJ cord-015569-vy49r1zd 917 12 loss loss NN cord-015569-vy49r1zd 917 13 caused cause VBN cord-015569-vy49r1zd 917 14 by by IN cord-015569-vy49r1zd 917 15 central central JJ cord-015569-vy49r1zd 917 16 pathway pathway NN cord-015569-vy49r1zd 917 17 damage damage NN cord-015569-vy49r1zd 917 18 . . . cord-015569-vy49r1zd 918 1 In in IN cord-015569-vy49r1zd 918 2 clinical clinical JJ cord-015569-vy49r1zd 918 3 practice practice NN cord-015569-vy49r1zd 918 4 , , , cord-015569-vy49r1zd 918 5 some some DT cord-015569-vy49r1zd 918 6 of of IN cord-015569-vy49r1zd 918 7 these these DT cord-015569-vy49r1zd 918 8 patients patient NNS cord-015569-vy49r1zd 918 9 show show VBP cord-015569-vy49r1zd 918 10 improvements improvement NNS cord-015569-vy49r1zd 918 11 in in IN cord-015569-vy49r1zd 918 12 olfactory olfactory JJ cord-015569-vy49r1zd 918 13 function function NN cord-015569-vy49r1zd 918 14 with with IN cord-015569-vy49r1zd 918 15 several several JJ cord-015569-vy49r1zd 918 16 years year NNS cord-015569-vy49r1zd 918 17 , , , cord-015569-vy49r1zd 918 18 thus thus RB cord-015569-vy49r1zd 918 19 long long JJ cord-015569-vy49r1zd 918 20 - - HYPH cord-015569-vy49r1zd 918 21 term term NN cord-015569-vy49r1zd 918 22 follow follow NN cord-015569-vy49r1zd 918 23 - - HYPH cord-015569-vy49r1zd 918 24 up up NN cord-015569-vy49r1zd 918 25 of of IN cord-015569-vy49r1zd 918 26 patients patient NNS cord-015569-vy49r1zd 918 27 is be VBZ cord-015569-vy49r1zd 918 28 needed need VBN cord-015569-vy49r1zd 918 29 to to TO cord-015569-vy49r1zd 918 30 develop develop VB cord-015569-vy49r1zd 918 31 new new JJ cord-015569-vy49r1zd 918 32 clinical clinical JJ cord-015569-vy49r1zd 918 33 studies study NNS cord-015569-vy49r1zd 918 34 . . . cord-015569-vy49r1zd 919 1 The the DT cord-015569-vy49r1zd 919 2 clinical clinical JJ cord-015569-vy49r1zd 919 3 study study NN cord-015569-vy49r1zd 919 4 of of IN cord-015569-vy49r1zd 919 5 patients patient NNS cord-015569-vy49r1zd 919 6 with with IN cord-015569-vy49r1zd 919 7 drug drug NN cord-015569-vy49r1zd 919 8 - - HYPH cord-015569-vy49r1zd 919 9 induced induce VBN cord-015569-vy49r1zd 919 10 olfactory olfactory JJ cord-015569-vy49r1zd 919 11 disturbances disturbance NNS cord-015569-vy49r1zd 919 12 cases case NNS cord-015569-vy49r1zd 919 13 ( ( -LRB- cord-015569-vy49r1zd 919 14 1.4 1.4 CD cord-015569-vy49r1zd 919 15 % % NN cord-015569-vy49r1zd 919 16 ) ) -RRB- cord-015569-vy49r1zd 919 17 of of IN cord-015569-vy49r1zd 919 18 drug drug NN cord-015569-vy49r1zd 919 19 - - HYPH cord-015569-vy49r1zd 919 20 induced induce VBN cord-015569-vy49r1zd 919 21 olfactory olfactory JJ cord-015569-vy49r1zd 919 22 disturbance disturbance NN cord-015569-vy49r1zd 919 23 were be VBD cord-015569-vy49r1zd 919 24 investigated investigate VBN cord-015569-vy49r1zd 919 25 . . . cord-015569-vy49r1zd 920 1 Anti anti JJ cord-015569-vy49r1zd 920 2 - - JJ cord-015569-vy49r1zd 920 3 cancer cancer JJ cord-015569-vy49r1zd 920 4 drugs drug NNS cord-015569-vy49r1zd 920 5 occupied occupy VBD cord-015569-vy49r1zd 920 6 81 81 CD cord-015569-vy49r1zd 920 7 % % NN cord-015569-vy49r1zd 920 8 in in IN cord-015569-vy49r1zd 920 9 the the DT cord-015569-vy49r1zd 920 10 frequency frequency NN cord-015569-vy49r1zd 920 11 of of IN cord-015569-vy49r1zd 920 12 causative causative JJ cord-015569-vy49r1zd 920 13 drugs drug NNS cord-015569-vy49r1zd 920 14 . . . cord-015569-vy49r1zd 921 1 Tegafur Tegafur NNP cord-015569-vy49r1zd 921 2 was be VBD cord-015569-vy49r1zd 921 3 most most RBS cord-015569-vy49r1zd 921 4 common common JJ cord-015569-vy49r1zd 921 5 in in IN cord-015569-vy49r1zd 921 6 the the DT cord-015569-vy49r1zd 921 7 causes cause NNS cord-015569-vy49r1zd 921 8 of of IN cord-015569-vy49r1zd 921 9 olfactory olfactory JJ cord-015569-vy49r1zd 921 10 disturbance disturbance NN cord-015569-vy49r1zd 921 11 by by IN cord-015569-vy49r1zd 921 12 anti anti JJ cord-015569-vy49r1zd 921 13 - - JJ cord-015569-vy49r1zd 921 14 cancer cancer JJ cord-015569-vy49r1zd 921 15 drugs drug NNS cord-015569-vy49r1zd 921 16 . . . cord-015569-vy49r1zd 922 1 We -PRON- PRP cord-015569-vy49r1zd 922 2 showed show VBD cord-015569-vy49r1zd 922 3 the the DT cord-015569-vy49r1zd 922 4 characteristics characteristic NNS cord-015569-vy49r1zd 922 5 of of IN cord-015569-vy49r1zd 922 6 drug drug NN cord-015569-vy49r1zd 922 7 - - HYPH cord-015569-vy49r1zd 922 8 induced induce VBN cord-015569-vy49r1zd 922 9 olfactory olfactory JJ cord-015569-vy49r1zd 922 10 disturbance disturbance NN cord-015569-vy49r1zd 922 11 by by IN cord-015569-vy49r1zd 922 12 Tegafur Tegafur NNP cord-015569-vy49r1zd 922 13 . . . cord-015569-vy49r1zd 923 1 A a DT cord-015569-vy49r1zd 923 2 total total NN cord-015569-vy49r1zd 923 3 of of IN cord-015569-vy49r1zd 923 4 21 21 CD cord-015569-vy49r1zd 923 5 patients patient NNS cord-015569-vy49r1zd 923 6 were be VBD cord-015569-vy49r1zd 923 7 identified identify VBN cord-015569-vy49r1zd 923 8 . . . cord-015569-vy49r1zd 924 1 The the DT cord-015569-vy49r1zd 924 2 averaged average VBN cord-015569-vy49r1zd 924 3 recognition recognition NN cord-015569-vy49r1zd 924 4 threshold threshold NN cord-015569-vy49r1zd 924 5 was be VBD cord-015569-vy49r1zd 924 6 5.29 5.29 CD cord-015569-vy49r1zd 924 7 and and CC cord-015569-vy49r1zd 924 8 the the DT cord-015569-vy49r1zd 924 9 averaged average VBN cord-015569-vy49r1zd 924 10 detection detection NN cord-015569-vy49r1zd 924 11 threshold threshold NN cord-015569-vy49r1zd 924 12 was be VBD cord-015569-vy49r1zd 924 13 4.67 4.67 CD cord-015569-vy49r1zd 924 14 in in IN cord-015569-vy49r1zd 924 15 T&T T&T NNP cord-015569-vy49r1zd 924 16 olfactometry olfactometry NN cord-015569-vy49r1zd 924 17 . . . cord-015569-vy49r1zd 925 1 After after IN cord-015569-vy49r1zd 925 2 treatment treatment NN cord-015569-vy49r1zd 925 3 , , , cord-015569-vy49r1zd 925 4 re re NNS cord-015569-vy49r1zd 925 5 - - NNS cord-015569-vy49r1zd 925 6 examinations examination NNS cord-015569-vy49r1zd 925 7 were be VBD cord-015569-vy49r1zd 925 8 performed perform VBN cord-015569-vy49r1zd 925 9 in in IN cord-015569-vy49r1zd 925 10 15 15 CD cord-015569-vy49r1zd 925 11 patients patient NNS cord-015569-vy49r1zd 925 12 . . . cord-015569-vy49r1zd 926 1 The the DT cord-015569-vy49r1zd 926 2 averaged averaged JJ cord-015569-vy49r1zd 926 3 recognition recognition NN