id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-007760-it9wach2	Jiao, Long R.	Suicide Gene Therapy in Liver Tumors	2004		.txt	text/plain	7100	352	51	have recently published the result of a phase I clinical trial using intratumoral injection of escalating doses of adenovirus-mediated suicide gene followed by intravenous GCV at a fixed dose in patients with colorectal liver metastases (13). The study seeks to determine the safety, biological efficacy, and effect of the Ad-TK-GCV dose in the locoregional gene therapy of primary malignant tumors of the liver. The following must be performed within 2 wk prior to study admission: complete medical history; physical examination; toxicity evaluation; performance status; height and weight and body surface area; laboratory screening (*eligibility criteria) for full blood count with differential, platelet count*, serum electrolytes (sodium, potassium, chloride, bicarbonate), urea, creatinine*, glucose, uric acid, albumin, liver function tests, including total protein, calcium, phosphorus, magnesium, aspartate transaminase (AST*), alanine transaminase (ALT*), total bilirubin*, alkaline phosphatase, lactate dehydrogenase (LDH), PT*, partial thomboplastin time (PTT*); urinalysis; α-fetoprotein; electrocardiogram (12-lead); chest X-ray (PA and lateral views); abdomen and pelvis CT or MRI scan.	./cache/cord-007760-it9wach2.txt	./txt/cord-007760-it9wach2.txt