id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-252781-06hs9pit	Lai, Wing-Fu	Cyclodextrins in non-viral gene delivery	2013-10-05		.txt	text/plain	6592	357	44	CDs have practical potential in gene delivery, but due to their failure to form stable complexes with plasmid DNA (pDNA) [40] , native CDs have limited transfection efficiency. Luciferase activity assays in K562 leukemia cells found that the transfection efficiency of the nanoparticles surface-modified with transferrin-PEG-AD conjugates was 4-fold higher than that of the unmodified counterparts [57] . In HEK293 cells, the polyrotaxanes fabricated showed higher transfection efficiency than PEI 25 kDa [58] , and deserve further evaluation as gene carriers for both in vitro and in vivo applications. The polymer showed more than 1-fold higher transfection efficiency, but lower cytotoxicity, than the PAMAM control (G4, with an ethylenediamine core) in human neuroblastoma SH-SY5Y cells. Efficient gene transfection in the neurotypic cells by star-shaped polymer consisting of b-cyclodextrin core and poly(amidoamine) dendron arms Enhancing effects of galactosylated dendrimer/a-cyclodextrin conjugates on gene transfer efficiency	./cache/cord-252781-06hs9pit.txt	./txt/cord-252781-06hs9pit.txt