id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312551-w4tps34p	Razvi, Mohammad H.	Transcriptional oncogenomic hot spots in Barrett's adenocarcinomas: Serial analysis of gene expression	2007-07-17		.txt	text/plain	5047	291	46	Analyses of the human transcriptome map of normal tissues have shown clustering of highly expressed genes in chromosomal domains (Caron et al., 2001) . In this study, we explored the BA transcriptome using SAGE and mapped gene-expression changes to chromosomal positions, thereby generating a map of transcriptional oncogenomic hot spots of this deadly cancer. We confirmed over-expression of ANPEP, ECGF1, PP1201, and EIF5A1 and downregulation of GKN1 in primary GEJ and lower esophageal adenocarcinoma samples (Table 5 , Fig. 2) . GKN1 shows downregulation ( 0.4-fold expression) whereas ANPEP, PP1201, EIF5A1, and ECGF1 demonstrate overexpression (!2.5 fold expression) in primary tumors as compared to normal tissue samples. Discovery of new markers of cancer through serial analysis of gene expression: Prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma	./cache/cord-312551-w4tps34p.txt	./txt/cord-312551-w4tps34p.txt