id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-315498-gpzee1f2	Parkinson, N.	Systematic review and meta-analysis identifies potential host therapeutic targets in COVID-19.	2020-09-01		.txt	text/plain	4964	296	46	2, 6, 7, 8, 9, 10 In this analysis we systematically identify and combine existing data from human betacoronavirus research to generate a comprehensive ranked list of host genes as a resource to inform further work on COVID-19. To identify existing literature which could provide informative datasets for host gene prioritisation, we conducted a systematic review of published studies and preprint manuscripts pertaining to host gene involvement in human betacoronavirus infection and associated disease. Results from identified studies, in the form of lists of implicated host factor genes, were combined using meta-analysis by information content (MAIC), 3 an approach we previously developed to identify host genes necessary for Influenza A virus (IAV) replication. Table 2 Candidate-gene human genetic studies < 5 hosts in virus group or control group in patient studies Meta-analyses, in silico anayses, re-analysis of data published elsewhere Potentially relevant pre-print manuscripts were identified by screening all papers categorised as COVID-19-related in the bioRxiv and medRxiv servers.	./cache/cord-315498-gpzee1f2.txt	./txt/cord-315498-gpzee1f2.txt