id author title date pages extension mime words sentences flesch summary cache txt cord-324720-acei0pn8 Howe, Charles L Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain 2012-03-09 .txt text/plain 5532 348 54 METHODS: The identity of brain-infiltrating leukocytes was determined using microscopy and flow cytometry at several acute time points following intracranial infection of mice with the Theiler's murine encephalomyelitis virus. Likewise, the population of CD45 hi cells could be distinguished by surface F4/80 expression, with some F4/80 + Figure 1 Histological evidence of rapid immune cell infiltration into the hippocampus of mice acutely infected with Theiler's murine encephalomyelitis virus (TMEV). We were unable to identify a population of inflammatory monocytes in the blood in the infected mice, suggesting either that these cells are not circulating at this time or that so many have been recruited to the brain that the Figure 2 Flow cytometric assessment of the infiltrate present in the brain of mice acutely infected with Theiler's murine encephalomyelitis virus (TMEV). ./cache/cord-324720-acei0pn8.txt ./txt/cord-324720-acei0pn8.txt