id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-008590-xivnsldf	Tartakoff, Alan M.	The Confined Function Model of the Golgi Complex: Center for Ordered Processing of Biosynthetic Products of the Rough Endoplasmic Reticulum	2008-04-14		.txt	text/plain	8142	387	47	These cisternae, in conjunction with other associated smoothsurfaced membranes, are responsible for executing net unidirectional intracellular transport (ICT) from the rough endoplasmic reticulum (RER) toward more distally located structures, e.g., lysosomes and the cell surface (24, 35, 40, 47, 85, 1 1 1, 134) . If they do not, given appropriate control experiments, they may be assigned to relatively late sub compartment^.^ The first indications that the site of interruption of ICT by monensin lies only part way across the GC came from study of the progress of N-linked oligosaccharide maturation of Ig (139) ; however, a recent use of monensin should be mentioned since it adds independent support for this idea (37) . The approaches used involved study of the effect of agents which block secretory protein exit from the RER (e.g., uncouplers) (130), correlation between the kinetics of ICT and cleavage, or, best of all, analysis of smooth microsomal or Golgi-enriched subcellular fractions [e.g., of hepatocytes (92, 102) or virally infected cells (68) ].	./cache/cord-008590-xivnsldf.txt	./txt/cord-008590-xivnsldf.txt