id	sid	tid	token	lemma	pos
cord-322516-wekvet6f	1	1	key	key	JJ
cord-322516-wekvet6f	1	2	:	:	:
cord-322516-wekvet6f	1	3	cord-322516-wekvet6f	cord-322516-wekvet6f	VBN
cord-322516-wekvet6f	1	4	authors	author	NNS
cord-322516-wekvet6f	1	5	:	:	:
cord-322516-wekvet6f	1	6	Maceyka	Maceyka	NNP
cord-322516-wekvet6f	1	7	,	,	,
cord-322516-wekvet6f	1	8	Michael	Michael	NNP
cord-322516-wekvet6f	1	9	;	;	:
cord-322516-wekvet6f	1	10	Machamer	Machamer	NNP
cord-322516-wekvet6f	1	11	,	,	,
cord-322516-wekvet6f	1	12	Carolyn	Carolyn	NNP
cord-322516-wekvet6f	1	13	E.	E.	NNP
cord-322516-wekvet6f	1	14	title	title	NN
cord-322516-wekvet6f	1	15	:	:	:
cord-322516-wekvet6f	2	1	Ceramide	Ceramide	NNP
cord-322516-wekvet6f	2	2	Accumulation	Accumulation	NNP
cord-322516-wekvet6f	2	3	Uncovers	uncover	VBZ
cord-322516-wekvet6f	2	4	a	a	DT
cord-322516-wekvet6f	2	5	Cycling	Cycling	NNP
cord-322516-wekvet6f	2	6	Pathway	Pathway	NNP
cord-322516-wekvet6f	2	7	for	for	IN
cord-322516-wekvet6f	2	8	the	the	DT
cord-322516-wekvet6f	2	9	cis	cis	NNP
cord-322516-wekvet6f	2	10	-	-	HYPH
cord-322516-wekvet6f	2	11	Golgi	Golgi	NNP
cord-322516-wekvet6f	2	12	Network	Network	NNP
cord-322516-wekvet6f	2	13	Marker	Marker	NNP
cord-322516-wekvet6f	2	14	,	,	,
cord-322516-wekvet6f	3	1	Infectious	Infectious	NNP
cord-322516-wekvet6f	3	2	Bronchitis	Bronchitis	NNP
cord-322516-wekvet6f	3	3	Virus	Virus	NNP
cord-322516-wekvet6f	3	4	M	M	NNP
cord-322516-wekvet6f	3	5	Protein	Protein	NNP
cord-322516-wekvet6f	3	6	date	date	NN
cord-322516-wekvet6f	3	7	:	:	:
cord-322516-wekvet6f	3	8	1997	1997	CD
cord-322516-wekvet6f	3	9	-	-	SYM
cord-322516-wekvet6f	3	10	12	12	CD
cord-322516-wekvet6f	3	11	-	-	SYM
cord-322516-wekvet6f	3	12	15	15	CD
cord-322516-wekvet6f	3	13	journal	journal	NN
cord-322516-wekvet6f	3	14	:	:	:
cord-322516-wekvet6f	3	15	J	J	NNP
cord-322516-wekvet6f	3	16	Cell	Cell	NNP
cord-322516-wekvet6f	3	17	Biol	Biol	NNP
cord-322516-wekvet6f	3	18	DOI	DOI	NNP
cord-322516-wekvet6f	3	19	:	:	:
cord-322516-wekvet6f	4	1	nan	nan	NNP
cord-322516-wekvet6f	4	2	sha	sha	NNP
cord-322516-wekvet6f	4	3	:	:	:
cord-322516-wekvet6f	4	4	f39b51bbd9ece044b1af4f83b6ff05053810e7d9	f39b51bbd9ece044b1af4f83b6ff05053810e7d9	NNP
cord-322516-wekvet6f	4	5	doc_id	doc_id	NNP
cord-322516-wekvet6f	4	6	:	:	:
cord-322516-wekvet6f	4	7	322516	322516	CD
cord-322516-wekvet6f	4	8	cord_uid	cord_uid	NNS
cord-322516-wekvet6f	4	9	:	:	:
cord-322516-wekvet6f	4	10	wekvet6f	wekvet6f	CD
cord-322516-wekvet6f	5	1	The	the	DT
cord-322516-wekvet6f	5	2	M	M	NNP
cord-322516-wekvet6f	5	3	glycoprotein	glycoprotein	NN
cord-322516-wekvet6f	5	4	from	from	IN
cord-322516-wekvet6f	5	5	the	the	DT
cord-322516-wekvet6f	5	6	avian	avian	JJ
cord-322516-wekvet6f	5	7	coronavirus	coronavirus	NN
cord-322516-wekvet6f	5	8	,	,	,
cord-322516-wekvet6f	5	9	infectious	infectious	JJ
cord-322516-wekvet6f	5	10	bronchitis	bronchitis	NN
cord-322516-wekvet6f	5	11	virus	virus	NN
cord-322516-wekvet6f	5	12	(	(	-LRB-
cord-322516-wekvet6f	5	13	IBV	IBV	NNP
cord-322516-wekvet6f	5	14	)	)	-RRB-
cord-322516-wekvet6f	5	15	,	,	,
cord-322516-wekvet6f	5	16	contains	contain	VBZ
cord-322516-wekvet6f	5	17	information	information	NN
cord-322516-wekvet6f	5	18	for	for	IN
cord-322516-wekvet6f	5	19	localization	localization	NN
cord-322516-wekvet6f	5	20	to	to	IN
cord-322516-wekvet6f	5	21	the	the	DT
cord-322516-wekvet6f	5	22	cis	cis	NNP
cord-322516-wekvet6f	5	23	-	-	HYPH
cord-322516-wekvet6f	5	24	Golgi	Golgi	NNP
cord-322516-wekvet6f	5	25	network	network	NN
cord-322516-wekvet6f	5	26	in	in	IN
cord-322516-wekvet6f	5	27	its	-PRON-	PRP$
cord-322516-wekvet6f	5	28	first	first	JJ
cord-322516-wekvet6f	5	29	transmembrane	transmembrane	NN
cord-322516-wekvet6f	5	30	domain	domain	NN
cord-322516-wekvet6f	5	31	.	.	.
cord-322516-wekvet6f	6	1	We	-PRON-	PRP
cord-322516-wekvet6f	6	2	hypothesize	hypothesize	VBP
cord-322516-wekvet6f	6	3	that	that	IN
cord-322516-wekvet6f	6	4	localization	localization	NN
cord-322516-wekvet6f	6	5	to	to	IN
cord-322516-wekvet6f	6	6	the	the	DT
cord-322516-wekvet6f	6	7	Golgi	Golgi	NNP
cord-322516-wekvet6f	6	8	complex	complex	NN
cord-322516-wekvet6f	6	9	may	may	MD
cord-322516-wekvet6f	6	10	depend	depend	VB
cord-322516-wekvet6f	6	11	in	in	IN
cord-322516-wekvet6f	6	12	part	part	NN
cord-322516-wekvet6f	6	13	on	on	IN
cord-322516-wekvet6f	6	14	specific	specific	JJ
cord-322516-wekvet6f	6	15	interactions	interaction	NNS
cord-322516-wekvet6f	6	16	between	between	IN
cord-322516-wekvet6f	6	17	protein	protein	NN
cord-322516-wekvet6f	6	18	transmembrane	transmembrane	NN
cord-322516-wekvet6f	6	19	domains	domain	NNS
cord-322516-wekvet6f	6	20	and	and	CC
cord-322516-wekvet6f	6	21	membrane	membrane	NN
cord-322516-wekvet6f	6	22	lipids	lipid	NNS
cord-322516-wekvet6f	6	23	.	.	.
cord-322516-wekvet6f	7	1	Because	because	IN
cord-322516-wekvet6f	7	2	the	the	DT
cord-322516-wekvet6f	7	3	site	site	NN
cord-322516-wekvet6f	7	4	of	of	IN
cord-322516-wekvet6f	7	5	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	7	6	synthesis	synthesis	NN
cord-322516-wekvet6f	7	7	overlaps	overlap	VBZ
cord-322516-wekvet6f	7	8	the	the	DT
cord-322516-wekvet6f	7	9	localization	localization	NN
cord-322516-wekvet6f	7	10	of	of	IN
cord-322516-wekvet6f	7	11	IBV	IBV	NNP
cord-322516-wekvet6f	7	12	M	M	NNP
cord-322516-wekvet6f	7	13	,	,	,
cord-322516-wekvet6f	7	14	we	-PRON-	PRP
cord-322516-wekvet6f	7	15	asked	ask	VBD
cord-322516-wekvet6f	7	16	whether	whether	IN
cord-322516-wekvet6f	7	17	perturbation	perturbation	NN
cord-322516-wekvet6f	7	18	of	of	IN
cord-322516-wekvet6f	7	19	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	7	20	affected	affect	VBN
cord-322516-wekvet6f	7	21	localization	localization	NN
cord-322516-wekvet6f	7	22	of	of	IN
cord-322516-wekvet6f	7	23	IBV	IBV	NNP
cord-322516-wekvet6f	7	24	M.	M.	NNP
cord-322516-wekvet6f	7	25	Short	short	JJ
cord-322516-wekvet6f	7	26	-	-	HYPH
cord-322516-wekvet6f	7	27	term	term	NN
cord-322516-wekvet6f	7	28	treatment	treatment	NN
cord-322516-wekvet6f	7	29	with	with	IN
cord-322516-wekvet6f	7	30	two	two	CD
cord-322516-wekvet6f	7	31	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	7	32	of	of	IN
cord-322516-wekvet6f	7	33	sphingolipid	sphingolipid	NNP
cord-322516-wekvet6f	7	34	synthesis	synthesis	NNP
cord-322516-wekvet6f	7	35	had	have	VBD
cord-322516-wekvet6f	7	36	no	no	DT
cord-322516-wekvet6f	7	37	effect	effect	NN
cord-322516-wekvet6f	7	38	on	on	IN
cord-322516-wekvet6f	7	39	localization	localization	NN
cord-322516-wekvet6f	7	40	of	of	IN
cord-322516-wekvet6f	7	41	IBV	IBV	NNP
cord-322516-wekvet6f	7	42	M	M	NNP
cord-322516-wekvet6f	7	43	or	or	CC
cord-322516-wekvet6f	7	44	other	other	JJ
cord-322516-wekvet6f	7	45	Golgi	Golgi	NNP
cord-322516-wekvet6f	7	46	markers	marker	NNS
cord-322516-wekvet6f	7	47	.	.	.
cord-322516-wekvet6f	8	1	Thus	thus	RB
cord-322516-wekvet6f	8	2	,	,	,
cord-322516-wekvet6f	8	3	ongoing	ongoing	JJ
cord-322516-wekvet6f	8	4	synthesis	synthesis	NN
cord-322516-wekvet6f	8	5	of	of	IN
cord-322516-wekvet6f	8	6	these	these	DT
cord-322516-wekvet6f	8	7	lipids	lipid	NNS
cord-322516-wekvet6f	8	8	was	be	VBD
cord-322516-wekvet6f	8	9	not	not	RB
cord-322516-wekvet6f	8	10	required	require	VBN
cord-322516-wekvet6f	8	11	for	for	IN
cord-322516-wekvet6f	8	12	proper	proper	JJ
cord-322516-wekvet6f	8	13	localization	localization	NN
cord-322516-wekvet6f	8	14	.	.	.
cord-322516-wekvet6f	9	1	Surprisingly	surprisingly	RB
cord-322516-wekvet6f	9	2	,	,	,
cord-322516-wekvet6f	9	3	a	a	DT
cord-322516-wekvet6f	9	4	third	third	JJ
cord-322516-wekvet6f	9	5	inhibitor	inhibitor	NN
cord-322516-wekvet6f	9	6	,	,	,
cord-322516-wekvet6f	9	7	d	d	NNP
cord-322516-wekvet6f	9	8	,	,	,
cord-322516-wekvet6f	9	9	l	l	NN
cord-322516-wekvet6f	9	10	-	-	HYPH
cord-322516-wekvet6f	9	11	threo-1-phenyl-2-decanoylamino-3-morpholino-	threo-1-phenyl-2-decanoylamino-3-morpholino-	NN
cord-322516-wekvet6f	9	12	1-propanol	1-propanol	CD
cord-322516-wekvet6f	9	13	(	(	-LRB-
cord-322516-wekvet6f	9	14	PDMP	PDMP	NNP
cord-322516-wekvet6f	9	15	)	)	-RRB-
cord-322516-wekvet6f	9	16	,	,	,
cord-322516-wekvet6f	9	17	shifted	shift	VBD
cord-322516-wekvet6f	9	18	the	the	DT
cord-322516-wekvet6f	9	19	steady	steady	JJ
cord-322516-wekvet6f	9	20	-	-	HYPH
cord-322516-wekvet6f	9	21	state	state	NN
cord-322516-wekvet6f	9	22	distribution	distribution	NN
cord-322516-wekvet6f	9	23	of	of	IN
cord-322516-wekvet6f	9	24	IBV	IBV	NNP
cord-322516-wekvet6f	9	25	M	M	NNP
cord-322516-wekvet6f	9	26	from	from	IN
cord-322516-wekvet6f	9	27	the	the	DT
cord-322516-wekvet6f	9	28	Golgi	Golgi	NNP
cord-322516-wekvet6f	9	29	complex	complex	NN
cord-322516-wekvet6f	9	30	to	to	IN
cord-322516-wekvet6f	9	31	the	the	DT
cord-322516-wekvet6f	9	32	ER	ER	NNP
cord-322516-wekvet6f	9	33	.	.	.
cord-322516-wekvet6f	10	1	This	this	DT
cord-322516-wekvet6f	10	2	effect	effect	NN
cord-322516-wekvet6f	10	3	was	be	VBD
cord-322516-wekvet6f	10	4	rapid	rapid	JJ
cord-322516-wekvet6f	10	5	and	and	CC
cord-322516-wekvet6f	10	6	reversible	reversible	JJ
cord-322516-wekvet6f	10	7	and	and	CC
cord-322516-wekvet6f	10	8	was	be	VBD
cord-322516-wekvet6f	10	9	also	also	RB
cord-322516-wekvet6f	10	10	observed	observe	VBN
cord-322516-wekvet6f	10	11	for	for	IN
cord-322516-wekvet6f	10	12	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	10	13	but	but	CC
cord-322516-wekvet6f	10	14	not	not	RB
cord-322516-wekvet6f	10	15	for	for	IN
cord-322516-wekvet6f	10	16	Golgi	Golgi	NNP
cord-322516-wekvet6f	10	17	stack	stack	NN
cord-322516-wekvet6f	10	18	proteins	protein	NNS
cord-322516-wekvet6f	10	19	.	.	.
cord-322516-wekvet6f	11	1	At	at	IN
cord-322516-wekvet6f	11	2	the	the	DT
cord-322516-wekvet6f	11	3	concentration	concentration	NN
cord-322516-wekvet6f	11	4	of	of	IN
cord-322516-wekvet6f	11	5	PDMP	PDMP	NNP
cord-322516-wekvet6f	11	6	used	use	VBD
cord-322516-wekvet6f	11	7	,	,	,
cord-322516-wekvet6f	11	8	conversion	conversion	NN
cord-322516-wekvet6f	11	9	of	of	IN
cord-322516-wekvet6f	11	10	ceramide	ceramide	NN
cord-322516-wekvet6f	11	11	into	into	IN
cord-322516-wekvet6f	11	12	both	both	CC
cord-322516-wekvet6f	11	13	glucosylceramide	glucosylceramide	NN
cord-322516-wekvet6f	11	14	and	and	CC
cord-322516-wekvet6f	11	15	sphingomyelin	sphingomyelin	NN
cord-322516-wekvet6f	11	16	was	be	VBD
cord-322516-wekvet6f	11	17	inhibited	inhibit	VBN
cord-322516-wekvet6f	11	18	.	.	.
cord-322516-wekvet6f	12	1	Pretreatment	pretreatment	NN
cord-322516-wekvet6f	12	2	with	with	IN
cord-322516-wekvet6f	12	3	upstream	upstream	JJ
cord-322516-wekvet6f	12	4	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	12	5	partially	partially	RB
cord-322516-wekvet6f	12	6	reversed	reverse	VBD
cord-322516-wekvet6f	12	7	the	the	DT
cord-322516-wekvet6f	12	8	effects	effect	NNS
cord-322516-wekvet6f	12	9	of	of	IN
cord-322516-wekvet6f	12	10	PDMP	PDMP	NNP
cord-322516-wekvet6f	12	11	,	,	,
cord-322516-wekvet6f	12	12	suggesting	suggest	VBG
cord-322516-wekvet6f	12	13	that	that	IN
cord-322516-wekvet6f	12	14	ceramide	ceramide	NN
cord-322516-wekvet6f	12	15	accumulation	accumulation	NN
cord-322516-wekvet6f	12	16	mediates	mediate	VBZ
cord-322516-wekvet6f	12	17	the	the	DT
cord-322516-wekvet6f	12	18	PDMP	PDMP	NNP
cord-322516-wekvet6f	12	19	-	-	HYPH
cord-322516-wekvet6f	12	20	induced	induce	VBN
cord-322516-wekvet6f	12	21	alterations	alteration	NNS
cord-322516-wekvet6f	12	22	.	.	.
cord-322516-wekvet6f	13	1	Indeed	indeed	RB
cord-322516-wekvet6f	13	2	,	,	,
cord-322516-wekvet6f	13	3	an	an	DT
cord-322516-wekvet6f	13	4	increase	increase	NN
cord-322516-wekvet6f	13	5	in	in	IN
cord-322516-wekvet6f	13	6	cellular	cellular	JJ
cord-322516-wekvet6f	13	7	ceramide	ceramide	NN
cord-322516-wekvet6f	13	8	was	be	VBD
cord-322516-wekvet6f	13	9	measured	measure	VBN
cord-322516-wekvet6f	13	10	in	in	IN
cord-322516-wekvet6f	13	11	PDMP	PDMP	NNP
cord-322516-wekvet6f	13	12	-	-	HYPH
cord-322516-wekvet6f	13	13	treated	treat	VBN
cord-322516-wekvet6f	13	14	cells	cell	NNS
cord-322516-wekvet6f	13	15	.	.	.
cord-322516-wekvet6f	14	1	We	-PRON-	PRP
cord-322516-wekvet6f	14	2	propose	propose	VBP
cord-322516-wekvet6f	14	3	that	that	IN
cord-322516-wekvet6f	14	4	IBV	IBV	NNP
cord-322516-wekvet6f	14	5	M	M	NNP
cord-322516-wekvet6f	14	6	is	be	VBZ
cord-322516-wekvet6f	14	7	at	at	IN
cord-322516-wekvet6f	14	8	least	least	JJS
cord-322516-wekvet6f	14	9	in	in	IN
cord-322516-wekvet6f	14	10	part	part	NN
cord-322516-wekvet6f	14	11	localized	localize	VBN
cord-322516-wekvet6f	14	12	by	by	IN
cord-322516-wekvet6f	14	13	retrieval	retrieval	NN
cord-322516-wekvet6f	14	14	mechanisms	mechanism	NNS
cord-322516-wekvet6f	14	15	.	.	.
cord-322516-wekvet6f	15	1	Further	further	RB
cord-322516-wekvet6f	15	2	,	,	,
cord-322516-wekvet6f	15	3	ceramide	ceramide	NN
cord-322516-wekvet6f	15	4	accumulation	accumulation	NN
cord-322516-wekvet6f	15	5	reveals	reveal	VBZ
cord-322516-wekvet6f	15	6	this	this	DT
cord-322516-wekvet6f	15	7	cycle	cycle	NN
cord-322516-wekvet6f	15	8	by	by	IN
cord-322516-wekvet6f	15	9	upsetting	upset	VBG
cord-322516-wekvet6f	15	10	the	the	DT
cord-322516-wekvet6f	15	11	balance	balance	NN
cord-322516-wekvet6f	15	12	of	of	IN
cord-322516-wekvet6f	15	13	anterograde	anterograde	JJ
cord-322516-wekvet6f	15	14	and	and	CC
cord-322516-wekvet6f	15	15	retrograde	retrograde	JJ
cord-322516-wekvet6f	15	16	traffic	traffic	NN
cord-322516-wekvet6f	16	1	and/	and/	NNP
cord-322516-wekvet6f	16	2	or	or	CC
cord-322516-wekvet6f	16	3	disrupting	disrupt	VBG
cord-322516-wekvet6f	16	4	retention	retention	NN
cord-322516-wekvet6f	16	5	by	by	IN
cord-322516-wekvet6f	16	6	altering	alter	VBG
cord-322516-wekvet6f	16	7	bilayer	bilayer	NN
cord-322516-wekvet6f	16	8	dynamics	dynamic	NNS
cord-322516-wekvet6f	16	9	.	.	.
cord-322516-wekvet6f	17	1	1-propanol	1-propanol	CD
cord-322516-wekvet6f	18	1	(	(	-LRB-
cord-322516-wekvet6f	18	2	PDMP	PDMP	NNP
cord-322516-wekvet6f	18	3	)	)	-RRB-
cord-322516-wekvet6f	18	4	,	,	,
cord-322516-wekvet6f	18	5	shifted	shift	VBD
cord-322516-wekvet6f	18	6	the	the	DT
cord-322516-wekvet6f	18	7	steady	steady	JJ
cord-322516-wekvet6f	18	8	-	-	HYPH
cord-322516-wekvet6f	18	9	state	state	NN
cord-322516-wekvet6f	18	10	distribution	distribution	NN
cord-322516-wekvet6f	18	11	of	of	IN
cord-322516-wekvet6f	18	12	IBV	IBV	NNP
cord-322516-wekvet6f	18	13	M	M	NNP
cord-322516-wekvet6f	18	14	from	from	IN
cord-322516-wekvet6f	18	15	the	the	DT
cord-322516-wekvet6f	18	16	Golgi	Golgi	NNP
cord-322516-wekvet6f	18	17	complex	complex	NN
cord-322516-wekvet6f	18	18	to	to	IN
cord-322516-wekvet6f	18	19	the	the	DT
cord-322516-wekvet6f	18	20	ER	ER	NNP
cord-322516-wekvet6f	18	21	.	.	.
cord-322516-wekvet6f	19	1	This	this	DT
cord-322516-wekvet6f	19	2	effect	effect	NN
cord-322516-wekvet6f	19	3	was	be	VBD
cord-322516-wekvet6f	19	4	rapid	rapid	JJ
cord-322516-wekvet6f	19	5	and	and	CC
cord-322516-wekvet6f	19	6	reversible	reversible	JJ
cord-322516-wekvet6f	19	7	and	and	CC
cord-322516-wekvet6f	19	8	was	be	VBD
cord-322516-wekvet6f	19	9	also	also	RB
cord-322516-wekvet6f	19	10	observed	observe	VBN
cord-322516-wekvet6f	19	11	for	for	IN
cord-322516-wekvet6f	19	12	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	19	13	but	but	CC
cord-322516-wekvet6f	19	14	not	not	RB
cord-322516-wekvet6f	19	15	for	for	IN
cord-322516-wekvet6f	19	16	Golgi	Golgi	NNP
cord-322516-wekvet6f	19	17	stack	stack	NN
cord-322516-wekvet6f	19	18	proteins	protein	NNS
cord-322516-wekvet6f	19	19	.	.	.
cord-322516-wekvet6f	20	1	At	at	IN
cord-322516-wekvet6f	20	2	the	the	DT
cord-322516-wekvet6f	20	3	concentration	concentration	NN
cord-322516-wekvet6f	20	4	of	of	IN
cord-322516-wekvet6f	20	5	PDMP	PDMP	NNP
cord-322516-wekvet6f	20	6	used	use	VBD
cord-322516-wekvet6f	20	7	,	,	,
cord-322516-wekvet6f	20	8	conversion	conversion	NN
cord-322516-wekvet6f	20	9	of	of	IN
cord-322516-wekvet6f	20	10	ceramide	ceramide	NN
cord-322516-wekvet6f	20	11	into	into	IN
cord-322516-wekvet6f	20	12	both	both	CC
cord-322516-wekvet6f	20	13	glucosylceramide	glucosylceramide	NN
cord-322516-wekvet6f	20	14	and	and	CC
cord-322516-wekvet6f	20	15	sphingomyelin	sphingomyelin	NN
cord-322516-wekvet6f	20	16	was	be	VBD
cord-322516-wekvet6f	20	17	inhibited	inhibit	VBN
cord-322516-wekvet6f	20	18	.	.	.
cord-322516-wekvet6f	21	1	Pretreatment	pretreatment	NN
cord-322516-wekvet6f	21	2	with	with	IN
cord-322516-wekvet6f	21	3	upstream	upstream	JJ
cord-322516-wekvet6f	21	4	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	21	5	partially	partially	RB
cord-322516-wekvet6f	21	6	reversed	reverse	VBD
cord-322516-wekvet6f	21	7	the	the	DT
cord-322516-wekvet6f	21	8	effects	effect	NNS
cord-322516-wekvet6f	21	9	of	of	IN
cord-322516-wekvet6f	21	10	PDMP	PDMP	NNP
cord-322516-wekvet6f	21	11	,	,	,
cord-322516-wekvet6f	21	12	suggesting	suggest	VBG
cord-322516-wekvet6f	21	13	that	that	IN
cord-322516-wekvet6f	21	14	ceramide	ceramide	NN
cord-322516-wekvet6f	21	15	accumulation	accumulation	NN
cord-322516-wekvet6f	21	16	mediates	mediate	VBZ
cord-322516-wekvet6f	21	17	the	the	DT
cord-322516-wekvet6f	21	18	PDMP	PDMP	NNP
cord-322516-wekvet6f	21	19	-	-	HYPH
cord-322516-wekvet6f	21	20	induced	induce	VBN
cord-322516-wekvet6f	21	21	alterations	alteration	NNS
cord-322516-wekvet6f	21	22	.	.	.
cord-322516-wekvet6f	22	1	Indeed	indeed	RB
cord-322516-wekvet6f	22	2	,	,	,
cord-322516-wekvet6f	22	3	an	an	DT
cord-322516-wekvet6f	22	4	increase	increase	NN
cord-322516-wekvet6f	22	5	in	in	IN
cord-322516-wekvet6f	22	6	cellular	cellular	JJ
cord-322516-wekvet6f	22	7	ceramide	ceramide	NN
cord-322516-wekvet6f	22	8	was	be	VBD
cord-322516-wekvet6f	22	9	measured	measure	VBN
cord-322516-wekvet6f	22	10	in	in	IN
cord-322516-wekvet6f	22	11	PDMP	PDMP	NNP
cord-322516-wekvet6f	22	12	-	-	HYPH
cord-322516-wekvet6f	22	13	treated	treat	VBN
cord-322516-wekvet6f	22	14	cells	cell	NNS
cord-322516-wekvet6f	22	15	.	.	.
cord-322516-wekvet6f	23	1	We	-PRON-	PRP
cord-322516-wekvet6f	23	2	propose	propose	VBP
cord-322516-wekvet6f	23	3	that	that	IN
cord-322516-wekvet6f	23	4	IBV	IBV	NNP
cord-322516-wekvet6f	23	5	M	M	NNP
cord-322516-wekvet6f	23	6	is	be	VBZ
cord-322516-wekvet6f	23	7	at	at	IN
cord-322516-wekvet6f	23	8	least	least	JJS
cord-322516-wekvet6f	23	9	in	in	IN
cord-322516-wekvet6f	23	10	part	part	NN
cord-322516-wekvet6f	23	11	localized	localize	VBN
cord-322516-wekvet6f	23	12	by	by	IN
cord-322516-wekvet6f	23	13	retrieval	retrieval	NN
cord-322516-wekvet6f	23	14	mechanisms	mechanism	NNS
cord-322516-wekvet6f	23	15	.	.	.
cord-322516-wekvet6f	24	1	Further	further	RB
cord-322516-wekvet6f	24	2	,	,	,
cord-322516-wekvet6f	24	3	ceramide	ceramide	NN
cord-322516-wekvet6f	24	4	accumulation	accumulation	NN
cord-322516-wekvet6f	24	5	reveals	reveal	VBZ
cord-322516-wekvet6f	24	6	this	this	DT
cord-322516-wekvet6f	24	7	cycle	cycle	NN
cord-322516-wekvet6f	24	8	by	by	IN
cord-322516-wekvet6f	24	9	upsetting	upset	VBG
cord-322516-wekvet6f	24	10	the	the	DT
cord-322516-wekvet6f	24	11	balance	balance	NN
cord-322516-wekvet6f	24	12	of	of	IN
cord-322516-wekvet6f	24	13	anterograde	anterograde	JJ
cord-322516-wekvet6f	24	14	and	and	CC
cord-322516-wekvet6f	24	15	retrograde	retrograde	JJ
cord-322516-wekvet6f	24	16	traffic	traffic	NN
cord-322516-wekvet6f	25	1	and/	and/	NNP
cord-322516-wekvet6f	25	2	or	or	CC
cord-322516-wekvet6f	25	3	disrupting	disrupt	VBG
cord-322516-wekvet6f	25	4	retention	retention	NN
cord-322516-wekvet6f	25	5	by	by	IN
cord-322516-wekvet6f	25	6	altering	alter	VBG
cord-322516-wekvet6f	25	7	bilayer	bilayer	NN
cord-322516-wekvet6f	25	8	dynamics	dynamic	NNS
cord-322516-wekvet6f	25	9	.	.	.
cord-322516-wekvet6f	26	1	T	T	NNP
cord-322516-wekvet6f	26	2	he	-PRON-	PRP
cord-322516-wekvet6f	26	3	organelles	organelle	VBZ
cord-322516-wekvet6f	26	4	of	of	IN
cord-322516-wekvet6f	26	5	the	the	DT
cord-322516-wekvet6f	26	6	classical	classical	JJ
cord-322516-wekvet6f	26	7	secretory	secretory	JJ
cord-322516-wekvet6f	26	8	pathway	pathway	NN
cord-322516-wekvet6f	26	9	must	must	MD
cord-322516-wekvet6f	26	10	maintain	maintain	VB
cord-322516-wekvet6f	26	11	their	-PRON-	PRP$
cord-322516-wekvet6f	26	12	identity	identity	NN
cord-322516-wekvet6f	26	13	despite	despite	IN
cord-322516-wekvet6f	26	14	a	a	DT
cord-322516-wekvet6f	26	15	large	large	JJ
cord-322516-wekvet6f	26	16	flux	flux	NN
cord-322516-wekvet6f	26	17	of	of	IN
cord-322516-wekvet6f	26	18	lipids	lipid	NNS
cord-322516-wekvet6f	26	19	and	and	CC
cord-322516-wekvet6f	26	20	proteins	protein	NNS
cord-322516-wekvet6f	26	21	.	.	.
cord-322516-wekvet6f	27	1	Two	two	CD
cord-322516-wekvet6f	27	2	models	model	NNS
cord-322516-wekvet6f	27	3	have	have	VBP
cord-322516-wekvet6f	27	4	emerged	emerge	VBN
cord-322516-wekvet6f	27	5	to	to	TO
cord-322516-wekvet6f	27	6	explain	explain	VB
cord-322516-wekvet6f	27	7	how	how	WRB
cord-322516-wekvet6f	27	8	proteins	protein	NNS
cord-322516-wekvet6f	27	9	can	can	MD
cord-322516-wekvet6f	27	10	be	be	VB
cord-322516-wekvet6f	27	11	maintained	maintain	VBN
cord-322516-wekvet6f	27	12	in	in	IN
cord-322516-wekvet6f	27	13	specific	specific	JJ
cord-322516-wekvet6f	27	14	compartments	compartment	NNS
cord-322516-wekvet6f	27	15	(	(	-LRB-
cord-322516-wekvet6f	27	16	Machamer	Machamer	NNP
cord-322516-wekvet6f	27	17	,	,	,
cord-322516-wekvet6f	27	18	1993	1993	CD
cord-322516-wekvet6f	27	19	;	;	:
cord-322516-wekvet6f	27	20	Nilsson	Nilsson	NNP
cord-322516-wekvet6f	27	21	and	and	CC
cord-322516-wekvet6f	27	22	Warren	Warren	NNP
cord-322516-wekvet6f	27	23	,	,	,
cord-322516-wekvet6f	27	24	1994	1994	CD
cord-322516-wekvet6f	27	25	)	)	-RRB-
cord-322516-wekvet6f	27	26	.	.	.
cord-322516-wekvet6f	28	1	The	the	DT
cord-322516-wekvet6f	28	2	retention	retention	NN
cord-322516-wekvet6f	28	3	model	model	NN
cord-322516-wekvet6f	28	4	proposes	propose	VBZ
cord-322516-wekvet6f	28	5	that	that	IN
cord-322516-wekvet6f	28	6	proteins	protein	NNS
cord-322516-wekvet6f	28	7	are	be	VBP
cord-322516-wekvet6f	28	8	efficiently	efficiently	RB
cord-322516-wekvet6f	28	9	anchored	anchor	VBN
cord-322516-wekvet6f	28	10	in	in	IN
cord-322516-wekvet6f	28	11	the	the	DT
cord-322516-wekvet6f	28	12	appropriate	appropriate	JJ
cord-322516-wekvet6f	28	13	compartment	compartment	NN
cord-322516-wekvet6f	28	14	.	.	.
cord-322516-wekvet6f	29	1	The	the	DT
cord-322516-wekvet6f	29	2	retrieval	retrieval	NN
cord-322516-wekvet6f	29	3	model	model	NN
cord-322516-wekvet6f	29	4	proposes	propose	VBZ
cord-322516-wekvet6f	29	5	that	that	IN
cord-322516-wekvet6f	29	6	proteins	protein	NNS
cord-322516-wekvet6f	29	7	are	be	VBP
cord-322516-wekvet6f	29	8	continually	continually	RB
cord-322516-wekvet6f	29	9	recycled	recycle	VBN
cord-322516-wekvet6f	29	10	from	from	IN
cord-322516-wekvet6f	29	11	later	later	JJ
cord-322516-wekvet6f	29	12	compartments	compartment	NNS
cord-322516-wekvet6f	29	13	.	.	.
cord-322516-wekvet6f	30	1	The	the	DT
cord-322516-wekvet6f	30	2	two	two	CD
cord-322516-wekvet6f	30	3	models	model	NNS
cord-322516-wekvet6f	30	4	are	be	VBP
cord-322516-wekvet6f	30	5	not	not	RB
cord-322516-wekvet6f	30	6	mutually	mutually	RB
cord-322516-wekvet6f	30	7	exclusive	exclusive	JJ
cord-322516-wekvet6f	30	8	;	;	:
cord-322516-wekvet6f	30	9	indeed	indeed	RB
cord-322516-wekvet6f	30	10	most	most	JJS
cord-322516-wekvet6f	30	11	proteins	protein	NNS
cord-322516-wekvet6f	30	12	within	within	IN
cord-322516-wekvet6f	30	13	the	the	DT
cord-322516-wekvet6f	30	14	secretory	secretory	JJ
cord-322516-wekvet6f	30	15	pathway	pathway	NN
cord-322516-wekvet6f	30	16	probably	probably	RB
cord-322516-wekvet6f	30	17	use	use	VBP
cord-322516-wekvet6f	30	18	both	both	DT
cord-322516-wekvet6f	30	19	mechanisms	mechanism	NNS
cord-322516-wekvet6f	30	20	for	for	IN
cord-322516-wekvet6f	30	21	localization	localization	NN
cord-322516-wekvet6f	30	22	,	,	,
cord-322516-wekvet6f	30	23	albeit	albeit	IN
cord-322516-wekvet6f	30	24	to	to	IN
cord-322516-wekvet6f	30	25	differing	differ	VBG
cord-322516-wekvet6f	30	26	extents	extent	NNS
cord-322516-wekvet6f	30	27	.	.	.
cord-322516-wekvet6f	31	1	An	an	DT
cord-322516-wekvet6f	31	2	example	example	NN
cord-322516-wekvet6f	31	3	of	of	IN
cord-322516-wekvet6f	31	4	this	this	DT
cord-322516-wekvet6f	31	5	is	be	VBZ
cord-322516-wekvet6f	31	6	the	the	DT
cord-322516-wekvet6f	31	7	localization	localization	NN
cord-322516-wekvet6f	31	8	of	of	IN
cord-322516-wekvet6f	31	9	the	the	DT
cord-322516-wekvet6f	31	10	ER	ER	NNP
cord-322516-wekvet6f	31	11	resident	resident	NN
cord-322516-wekvet6f	31	12	protein	protein	NN
cord-322516-wekvet6f	31	13	BiP	BiP	NNP
cord-322516-wekvet6f	31	14	,	,	,
cord-322516-wekvet6f	31	15	which	which	WDT
cord-322516-wekvet6f	31	16	contains	contain	VBZ
cord-322516-wekvet6f	31	17	a	a	DT
cord-322516-wekvet6f	31	18	KDEL	KDEL	NNP
cord-322516-wekvet6f	31	19	retrieval	retrieval	NN
cord-322516-wekvet6f	31	20	signal	signal	NN
cord-322516-wekvet6f	31	21	but	but	CC
cord-322516-wekvet6f	31	22	is	be	VBZ
cord-322516-wekvet6f	31	23	only	only	RB
cord-322516-wekvet6f	31	24	slowly	slowly	RB
cord-322516-wekvet6f	31	25	secreted	secrete	VBN
cord-322516-wekvet6f	31	26	when	when	WRB
cord-322516-wekvet6f	31	27	this	this	DT
cord-322516-wekvet6f	31	28	signal	signal	NN
cord-322516-wekvet6f	31	29	is	be	VBZ
cord-322516-wekvet6f	31	30	removed	remove	VBN
cord-322516-wekvet6f	31	31	(	(	-LRB-
cord-322516-wekvet6f	31	32	Munro	Munro	NNP
cord-322516-wekvet6f	31	33	and	and	CC
cord-322516-wekvet6f	31	34	Pelham	Pelham	NNP
cord-322516-wekvet6f	31	35	,	,	,
cord-322516-wekvet6f	31	36	1987	1987	CD
cord-322516-wekvet6f	31	37	)	)	-RRB-
cord-322516-wekvet6f	31	38	.	.	.
cord-322516-wekvet6f	32	1	This	this	DT
cord-322516-wekvet6f	32	2	suggests	suggest	VBZ
cord-322516-wekvet6f	32	3	that	that	IN
cord-322516-wekvet6f	32	4	other	other	JJ
cord-322516-wekvet6f	32	5	parts	part	NNS
cord-322516-wekvet6f	32	6	of	of	IN
cord-322516-wekvet6f	32	7	the	the	DT
cord-322516-wekvet6f	32	8	molecule	molecule	NN
cord-322516-wekvet6f	32	9	may	may	MD
cord-322516-wekvet6f	32	10	contain	contain	VB
cord-322516-wekvet6f	32	11	retention	retention	NN
cord-322516-wekvet6f	32	12	information	information	NN
cord-322516-wekvet6f	32	13	.	.	.
cord-322516-wekvet6f	33	1	The	the	DT
cord-322516-wekvet6f	33	2	M	M	NNP
cord-322516-wekvet6f	33	3	glycoprotein	glycoprotein	NN
cord-322516-wekvet6f	33	4	from	from	IN
cord-322516-wekvet6f	33	5	the	the	DT
cord-322516-wekvet6f	33	6	avian	avian	JJ
cord-322516-wekvet6f	33	7	coronavirus	coronavirus	NN
cord-322516-wekvet6f	33	8	,	,	,
cord-322516-wekvet6f	33	9	infectious	infectious	JJ
cord-322516-wekvet6f	33	10	bronchitis	bronchitis	NN
cord-322516-wekvet6f	33	11	virus	virus	NN
cord-322516-wekvet6f	33	12	(	(	-LRB-
cord-322516-wekvet6f	33	13	IBV	IBV	NNP
cord-322516-wekvet6f	33	14	)	)	-RRB-
cord-322516-wekvet6f	33	15	,	,	,
cord-322516-wekvet6f	33	16	1	1	CD
cord-322516-wekvet6f	33	17	is	be	VBZ
cord-322516-wekvet6f	33	18	a	a	DT
cord-322516-wekvet6f	33	19	model	model	NN
cord-322516-wekvet6f	33	20	protein	protein	NN
cord-322516-wekvet6f	33	21	for	for	IN
cord-322516-wekvet6f	33	22	studying	study	VBG
cord-322516-wekvet6f	33	23	localization	localization	NN
cord-322516-wekvet6f	33	24	to	to	IN
cord-322516-wekvet6f	33	25	the	the	DT
cord-322516-wekvet6f	33	26	early	early	JJ
cord-322516-wekvet6f	33	27	secretory	secretory	JJ
cord-322516-wekvet6f	33	28	pathway	pathway	NN
cord-322516-wekvet6f	33	29	.	.	.
cord-322516-wekvet6f	34	1	Immunoelectron	Immunoelectron	NNP
cord-322516-wekvet6f	34	2	microscopy	microscopy	NNS
cord-322516-wekvet6f	34	3	showed	show	VBD
cord-322516-wekvet6f	34	4	that	that	IN
cord-322516-wekvet6f	34	5	IBV	IBV	NNP
cord-322516-wekvet6f	34	6	M	M	NNP
cord-322516-wekvet6f	34	7	expressed	express	VBD
cord-322516-wekvet6f	34	8	in	in	IN
cord-322516-wekvet6f	34	9	the	the	DT
cord-322516-wekvet6f	34	10	absence	absence	NN
cord-322516-wekvet6f	34	11	of	of	IN
cord-322516-wekvet6f	34	12	other	other	JJ
cord-322516-wekvet6f	34	13	IBV	IBV	NNP
cord-322516-wekvet6f	34	14	proteins	protein	NNS
cord-322516-wekvet6f	34	15	was	be	VBD
cord-322516-wekvet6f	34	16	found	find	VBN
cord-322516-wekvet6f	34	17	in	in	IN
cord-322516-wekvet6f	34	18	the	the	DT
cord-322516-wekvet6f	34	19	tubulovesicular	tubulovesicular	NNP
cord-322516-wekvet6f	34	20	structures	structure	NNS
cord-322516-wekvet6f	34	21	at	at	IN
cord-322516-wekvet6f	34	22	the	the	DT
cord-322516-wekvet6f	34	23	entry	entry	NN
cord-322516-wekvet6f	34	24	or	or	CC
cord-322516-wekvet6f	34	25	cis	cis	JJ
cord-322516-wekvet6f	34	26	face	face	NN
cord-322516-wekvet6f	34	27	of	of	IN
cord-322516-wekvet6f	34	28	the	the	DT
cord-322516-wekvet6f	34	29	Golgi	Golgi	NNP
cord-322516-wekvet6f	34	30	stack	stack	NN
cord-322516-wekvet6f	34	31	,	,	,
cord-322516-wekvet6f	34	32	as	as	RB
cord-322516-wekvet6f	34	33	well	well	RB
cord-322516-wekvet6f	34	34	as	as	IN
cord-322516-wekvet6f	34	35	the	the	DT
cord-322516-wekvet6f	34	36	first	first	JJ
cord-322516-wekvet6f	34	37	or	or	CC
cord-322516-wekvet6f	34	38	second	second	JJ
cord-322516-wekvet6f	34	39	cisterna	cisterna	NN
cord-322516-wekvet6f	34	40	of	of	IN
cord-322516-wekvet6f	34	41	the	the	DT
cord-322516-wekvet6f	34	42	Golgi	Golgi	NNP
cord-322516-wekvet6f	34	43	stack	stack	NN
cord-322516-wekvet6f	35	1	(	(	-LRB-
cord-322516-wekvet6f	35	2	Machamer	Machamer	NNP
cord-322516-wekvet6f	35	3	et	et	NNP
cord-322516-wekvet6f	35	4	al	al	NNP
cord-322516-wekvet6f	35	5	.	.	.
cord-322516-wekvet6f	36	1	,	,	,
cord-322516-wekvet6f	36	2	1990	1990	CD
cord-322516-wekvet6f	36	3	;	;	:
cord-322516-wekvet6f	36	4	Sodeik	Sodeik	NNP
cord-322516-wekvet6f	36	5	et	et	NNP
cord-322516-wekvet6f	36	6	al	al	NNP
cord-322516-wekvet6f	36	7	.	.	NNP
cord-322516-wekvet6f	36	8	,	,	,
cord-322516-wekvet6f	36	9	1993	1993	CD
cord-322516-wekvet6f	36	10	)	)	-RRB-
cord-322516-wekvet6f	36	11	.	.	.
cord-322516-wekvet6f	37	1	We	-PRON-	PRP
cord-322516-wekvet6f	37	2	will	will	MD
cord-322516-wekvet6f	37	3	refer	refer	VB
cord-322516-wekvet6f	37	4	to	to	IN
cord-322516-wekvet6f	37	5	this	this	DT
cord-322516-wekvet6f	37	6	region	region	NN
cord-322516-wekvet6f	37	7	as	as	IN
cord-322516-wekvet6f	37	8	the	the	DT
cord-322516-wekvet6f	37	9	cis	cis	NNP
cord-322516-wekvet6f	37	10	-Golgi	-Golgi	NNP
cord-322516-wekvet6f	37	11	network	network	NN
cord-322516-wekvet6f	37	12	(	(	-LRB-
cord-322516-wekvet6f	37	13	CGN	CGN	NNP
cord-322516-wekvet6f	37	14	;	;	:
cord-322516-wekvet6f	37	15	Mellman	Mellman	NNP
cord-322516-wekvet6f	37	16	and	and	CC
cord-322516-wekvet6f	37	17	Simons	Simons	NNP
cord-322516-wekvet6f	37	18	,	,	,
cord-322516-wekvet6f	37	19	1992	1992	CD
cord-322516-wekvet6f	37	20	)	)	-RRB-
cord-322516-wekvet6f	37	21	.	.	.
cord-322516-wekvet6f	38	1	Defined	define	VBN
cord-322516-wekvet6f	38	2	in	in	IN
cord-322516-wekvet6f	38	3	this	this	DT
cord-322516-wekvet6f	38	4	way	way	NN
cord-322516-wekvet6f	38	5	,	,	,
cord-322516-wekvet6f	38	6	we	-PRON-	PRP
cord-322516-wekvet6f	38	7	would	would	MD
cord-322516-wekvet6f	38	8	consider	consider	VB
cord-322516-wekvet6f	38	9	the	the	DT
cord-322516-wekvet6f	38	10	CGN	CGN	NNP
cord-322516-wekvet6f	38	11	to	to	IN
cord-322516-wekvet6f	38	12	at	at	IN
cord-322516-wekvet6f	38	13	least	least	JJS
cord-322516-wekvet6f	38	14	partially	partially	RB
cord-322516-wekvet6f	38	15	overlap	overlap	VB
cord-322516-wekvet6f	38	16	with	with	IN
cord-322516-wekvet6f	38	17	the	the	DT
cord-322516-wekvet6f	38	18	intermediate	intermediate	JJ
cord-322516-wekvet6f	38	19	compartment	compartment	NN
cord-322516-wekvet6f	38	20	(	(	-LRB-
cord-322516-wekvet6f	38	21	IC	IC	NNP
cord-322516-wekvet6f	38	22	)	)	-RRB-
cord-322516-wekvet6f	38	23	,	,	,
cord-322516-wekvet6f	38	24	defined	define	VBN
cord-322516-wekvet6f	38	25	by	by	IN
cord-322516-wekvet6f	38	26	such	such	JJ
cord-322516-wekvet6f	38	27	markers	marker	NNS
cord-322516-wekvet6f	38	28	as	as	IN
cord-322516-wekvet6f	38	29	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	38	30	or	or	CC
cord-322516-wekvet6f	38	31	p58	p58	NNP
cord-322516-wekvet6f	38	32	(	(	-LRB-
cord-322516-wekvet6f	38	33	Schweizer	Schweizer	NNP
cord-322516-wekvet6f	38	34	et	et	NNP
cord-322516-wekvet6f	38	35	al	al	NNP
cord-322516-wekvet6f	38	36	.	.	NNP
cord-322516-wekvet6f	38	37	,	,	,
cord-322516-wekvet6f	38	38	1988	1988	CD
cord-322516-wekvet6f	38	39	;	;	:
cord-322516-wekvet6f	38	40	Lahtinen	Lahtinen	NNP
cord-322516-wekvet6f	38	41	et	et	NNP
cord-322516-wekvet6f	38	42	al	al	NNP
cord-322516-wekvet6f	38	43	.	.	NNP
cord-322516-wekvet6f	38	44	,	,	,
cord-322516-wekvet6f	38	45	1996	1996	CD
cord-322516-wekvet6f	38	46	)	)	-RRB-
cord-322516-wekvet6f	38	47	.	.	.
cord-322516-wekvet6f	39	1	The	the	DT
cord-322516-wekvet6f	39	2	first	first	JJ
cord-322516-wekvet6f	39	3	transmembrane	transmembrane	NN
cord-322516-wekvet6f	39	4	domain	domain	NN
cord-322516-wekvet6f	39	5	of	of	IN
cord-322516-wekvet6f	39	6	IBV	IBV	NNP
cord-322516-wekvet6f	39	7	M	M	NNP
cord-322516-wekvet6f	39	8	is	be	VBZ
cord-322516-wekvet6f	39	9	sufficient	sufficient	JJ
cord-322516-wekvet6f	39	10	to	to	TO
cord-322516-wekvet6f	39	11	target	target	VB
cord-322516-wekvet6f	39	12	chimeric	chimeric	JJ
cord-322516-wekvet6f	39	13	proteins	protein	NNS
cord-322516-wekvet6f	39	14	to	to	IN
cord-322516-wekvet6f	39	15	the	the	DT
cord-322516-wekvet6f	39	16	CGN	CGN	NNP
cord-322516-wekvet6f	39	17	(	(	-LRB-
cord-322516-wekvet6f	39	18	Swift	Swift	NNP
cord-322516-wekvet6f	39	19	and	and	CC
cord-322516-wekvet6f	39	20	Machamer	Machamer	NNP
cord-322516-wekvet6f	39	21	,	,	,
cord-322516-wekvet6f	39	22	1991	1991	CD
cord-322516-wekvet6f	39	23	;	;	:
cord-322516-wekvet6f	40	1	Machamer	Machamer	NNP
cord-322516-wekvet6f	40	2	et	et	NNP
cord-322516-wekvet6f	40	3	al	al	NNP
cord-322516-wekvet6f	40	4	.	.	NNP
cord-322516-wekvet6f	40	5	,	,	,
cord-322516-wekvet6f	40	6	1993	1993	CD
cord-322516-wekvet6f	40	7	)	)	-RRB-
cord-322516-wekvet6f	40	8	.	.	.
cord-322516-wekvet6f	41	1	Although	although	IN
cord-322516-wekvet6f	41	2	the	the	DT
cord-322516-wekvet6f	41	3	transmembrane	transmembrane	NN
cord-322516-wekvet6f	41	4	domains	domain	NNS
cord-322516-wekvet6f	41	5	of	of	IN
cord-322516-wekvet6f	41	6	other	other	JJ
cord-322516-wekvet6f	41	7	Golgi	Golgi	NNP
cord-322516-wekvet6f	41	8	proteins	protein	NNS
cord-322516-wekvet6f	41	9	also	also	RB
cord-322516-wekvet6f	41	10	contain	contain	VBP
cord-322516-wekvet6f	41	11	targeting	target	VBG
cord-322516-wekvet6f	41	12	information	information	NN
cord-322516-wekvet6f	41	13	,	,	,
cord-322516-wekvet6f	41	14	no	no	DT
cord-322516-wekvet6f	41	15	consensus	consensus	NN
cord-322516-wekvet6f	41	16	motif	motif	NN
cord-322516-wekvet6f	41	17	for	for	IN
cord-322516-wekvet6f	41	18	localization	localization	NN
cord-322516-wekvet6f	41	19	has	have	VBZ
cord-322516-wekvet6f	41	20	been	be	VBN
cord-322516-wekvet6f	41	21	identified	identify	VBN
cord-322516-wekvet6f	41	22	(	(	-LRB-
cord-322516-wekvet6f	41	23	for	for	IN
cord-322516-wekvet6f	41	24	review	review	NN
cord-322516-wekvet6f	41	25	see	see	VB
cord-322516-wekvet6f	41	26	Colley	Colley	NNP
cord-322516-wekvet6f	41	27	,	,	,
cord-322516-wekvet6f	41	28	1997	1997	CD
cord-322516-wekvet6f	41	29	)	)	-RRB-
cord-322516-wekvet6f	41	30	.	.	.
cord-322516-wekvet6f	42	1	We	-PRON-	PRP
cord-322516-wekvet6f	42	2	are	be	VBP
cord-322516-wekvet6f	42	3	intrigued	intrigued	JJ
cord-322516-wekvet6f	42	4	by	by	IN
cord-322516-wekvet6f	42	5	the	the	DT
cord-322516-wekvet6f	42	6	possibility	possibility	NN
cord-322516-wekvet6f	42	7	that	that	IN
cord-322516-wekvet6f	42	8	the	the	DT
cord-322516-wekvet6f	42	9	targeting	targeting	NN
cord-322516-wekvet6f	42	10	of	of	IN
cord-322516-wekvet6f	42	11	Golgi	Golgi	NNP
cord-322516-wekvet6f	42	12	membrane	membrane	NN
cord-322516-wekvet6f	42	13	proteins	protein	NNS
cord-322516-wekvet6f	42	14	may	may	MD
cord-322516-wekvet6f	42	15	in	in	IN
cord-322516-wekvet6f	42	16	part	part	NN
cord-322516-wekvet6f	42	17	depend	depend	VB
cord-322516-wekvet6f	42	18	on	on	IN
cord-322516-wekvet6f	42	19	interactions	interaction	NNS
cord-322516-wekvet6f	42	20	between	between	IN
cord-322516-wekvet6f	42	21	their	-PRON-	PRP$
cord-322516-wekvet6f	42	22	transmembrane	transmembrane	NN
cord-322516-wekvet6f	42	23	domains	domain	NNS
cord-322516-wekvet6f	42	24	and	and	CC
cord-322516-wekvet6f	42	25	specific	specific	JJ
cord-322516-wekvet6f	42	26	membrane	membrane	NN
cord-322516-wekvet6f	42	27	lipids	lipid	NNS
cord-322516-wekvet6f	42	28	.	.	.
cord-322516-wekvet6f	43	1	Independent	independent	JJ
cord-322516-wekvet6f	43	2	studies	study	NNS
cord-322516-wekvet6f	43	3	demonstrate	demonstrate	VBP
cord-322516-wekvet6f	43	4	that	that	IN
cord-322516-wekvet6f	43	5	the	the	DT
cord-322516-wekvet6f	43	6	lipid	lipid	NN
cord-322516-wekvet6f	43	7	compositions	composition	NNS
cord-322516-wekvet6f	43	8	of	of	IN
cord-322516-wekvet6f	43	9	membranes	membrane	NNS
cord-322516-wekvet6f	43	10	differ	differ	VBP
cord-322516-wekvet6f	43	11	at	at	IN
cord-322516-wekvet6f	43	12	each	each	DT
cord-322516-wekvet6f	43	13	stage	stage	NN
cord-322516-wekvet6f	43	14	of	of	IN
cord-322516-wekvet6f	43	15	the	the	DT
cord-322516-wekvet6f	43	16	secretory	secretory	JJ
cord-322516-wekvet6f	43	17	pathway	pathway	NN
cord-322516-wekvet6f	43	18	(	(	-LRB-
cord-322516-wekvet6f	43	19	Keenan	Keenan	NNP
cord-322516-wekvet6f	43	20	and	and	CC
cord-322516-wekvet6f	43	21	Morre	Morre	NNP
cord-322516-wekvet6f	43	22	,	,	,
cord-322516-wekvet6f	43	23	1970	1970	CD
cord-322516-wekvet6f	43	24	;	;	:
cord-322516-wekvet6f	43	25	Cluett	Cluett	NNP
cord-322516-wekvet6f	43	26	et	et	NNP
cord-322516-wekvet6f	43	27	al	al	NNP
cord-322516-wekvet6f	43	28	.	.	NNP
cord-322516-wekvet6f	43	29	,	,	,
cord-322516-wekvet6f	43	30	1997	1997	CD
cord-322516-wekvet6f	43	31	;	;	:
cord-322516-wekvet6f	43	32	 	 	_SP
cord-322516-wekvet6f	43	33	for	for	IN
cord-322516-wekvet6f	43	34	review	review	NN
cord-322516-wekvet6f	43	35	see	see	VB
cord-322516-wekvet6f	43	36	van	van	NNP
cord-322516-wekvet6f	43	37	Meer	Meer	NNP
cord-322516-wekvet6f	43	38	,	,	,
cord-322516-wekvet6f	43	39	1993	1993	CD
cord-322516-wekvet6f	43	40	)	)	-RRB-
cord-322516-wekvet6f	43	41	.	.	.
cord-322516-wekvet6f	44	1	Sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	44	2	,	,	,
cord-322516-wekvet6f	44	3	including	include	VBG
cord-322516-wekvet6f	44	4	sphingomyelin	sphingomyelin	NN
cord-322516-wekvet6f	44	5	(	(	-LRB-
cord-322516-wekvet6f	44	6	SM	sm	NN
cord-322516-wekvet6f	44	7	)	)	-RRB-
cord-322516-wekvet6f	44	8	and	and	CC
cord-322516-wekvet6f	44	9	glucosylceramide	glucosylceramide	NN
cord-322516-wekvet6f	44	10	(	(	-LRB-
cord-322516-wekvet6f	44	11	GlcCer	glccer	NN
cord-322516-wekvet6f	44	12	)	)	-RRB-
cord-322516-wekvet6f	44	13	,	,	,
cord-322516-wekvet6f	44	14	the	the	DT
cord-322516-wekvet6f	44	15	precursor	precursor	NN
cord-322516-wekvet6f	44	16	to	to	IN
cord-322516-wekvet6f	44	17	all	all	DT
cord-322516-wekvet6f	44	18	gangliosides	ganglioside	NNS
cord-322516-wekvet6f	44	19	,	,	,
cord-322516-wekvet6f	44	20	are	be	VBP
cord-322516-wekvet6f	44	21	one	one	CD
cord-322516-wekvet6f	44	22	class	class	NN
cord-322516-wekvet6f	44	23	of	of	IN
cord-322516-wekvet6f	44	24	lipids	lipid	NNS
cord-322516-wekvet6f	44	25	thought	think	VBN
cord-322516-wekvet6f	44	26	to	to	TO
cord-322516-wekvet6f	44	27	increase	increase	VB
cord-322516-wekvet6f	44	28	in	in	IN
cord-322516-wekvet6f	44	29	relative	relative	JJ
cord-322516-wekvet6f	44	30	concentration	concentration	NN
cord-322516-wekvet6f	44	31	through	through	IN
cord-322516-wekvet6f	44	32	the	the	DT
cord-322516-wekvet6f	44	33	secretory	secretory	JJ
cord-322516-wekvet6f	44	34	pathway	pathway	NN
cord-322516-wekvet6f	44	35	.	.	.
cord-322516-wekvet6f	45	1	Ceramide	ceramide	NN
cord-322516-wekvet6f	45	2	,	,	,
cord-322516-wekvet6f	45	3	the	the	DT
cord-322516-wekvet6f	45	4	precursor	precursor	NN
cord-322516-wekvet6f	45	5	of	of	IN
cord-322516-wekvet6f	45	6	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	45	7	,	,	,
cord-322516-wekvet6f	45	8	is	be	VBZ
cord-322516-wekvet6f	45	9	synthesized	synthesize	VBN
cord-322516-wekvet6f	45	10	in	in	IN
cord-322516-wekvet6f	45	11	the	the	DT
cord-322516-wekvet6f	45	12	ER	er	NN
cord-322516-wekvet6f	45	13	.	.	.
cord-322516-wekvet6f	46	1	In	in	IN
cord-322516-wekvet6f	46	2	rat	rat	NN
cord-322516-wekvet6f	46	3	liver	liver	NN
cord-322516-wekvet6f	46	4	,	,	,
cord-322516-wekvet6f	46	5	ceramide	ceramide	NN
cord-322516-wekvet6f	46	6	is	be	VBZ
cord-322516-wekvet6f	46	7	converted	convert	VBN
cord-322516-wekvet6f	46	8	into	into	IN
cord-322516-wekvet6f	46	9	the	the	DT
cord-322516-wekvet6f	46	10	different	different	JJ
cord-322516-wekvet6f	46	11	classes	class	NNS
cord-322516-wekvet6f	46	12	of	of	IN
cord-322516-wekvet6f	46	13	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	46	14	by	by	IN
cord-322516-wekvet6f	46	15	enzymes	enzyme	NNS
cord-322516-wekvet6f	46	16	localized	localize	VBN
cord-322516-wekvet6f	46	17	to	to	IN
cord-322516-wekvet6f	46	18	the	the	DT
cord-322516-wekvet6f	46	19	CGN	CGN	NNP
cord-322516-wekvet6f	46	20	and	and	CC
cord-322516-wekvet6f	46	21	the	the	DT
cord-322516-wekvet6f	46	22	cis	cis	NNP
cord-322516-wekvet6f	46	23	-and	-and	HYPH
cord-322516-wekvet6f	46	24	medial	medial	JJ
cord-322516-wekvet6f	46	25	-Golgi	-Golgi	NNP
cord-322516-wekvet6f	46	26	cisternae	cisternae	NNP
cord-322516-wekvet6f	47	1	(	(	-LRB-
cord-322516-wekvet6f	47	2	Futerman	Futerman	NNP
cord-322516-wekvet6f	47	3	et	et	FW
cord-322516-wekvet6f	47	4	al	al	NNP
cord-322516-wekvet6f	47	5	.	.	NNP
cord-322516-wekvet6f	47	6	,	,	,
cord-322516-wekvet6f	47	7	1990	1990	CD
cord-322516-wekvet6f	47	8	;	;	:
cord-322516-wekvet6f	48	1	Futerman	Futerman	NNP
cord-322516-wekvet6f	48	2	and	and	CC
cord-322516-wekvet6f	48	3	Pagano	Pagano	NNP
cord-322516-wekvet6f	48	4	,	,	,
cord-322516-wekvet6f	48	5	1991	1991	CD
cord-322516-wekvet6f	48	6	)	)	-RRB-
cord-322516-wekvet6f	48	7	.	.	.
cord-322516-wekvet6f	49	1	When	when	WRB
cord-322516-wekvet6f	49	2	expressed	express	VBN
cord-322516-wekvet6f	49	3	from	from	IN
cord-322516-wekvet6f	49	4	a	a	DT
cord-322516-wekvet6f	49	5	recombinant	recombinant	JJ
cord-322516-wekvet6f	49	6	vaccinia	vaccinia	NN
cord-322516-wekvet6f	49	7	virus	virus	NN
cord-322516-wekvet6f	49	8	,	,	,
cord-322516-wekvet6f	49	9	IBV	IBV	NNP
cord-322516-wekvet6f	49	10	M	M	NNP
cord-322516-wekvet6f	49	11	is	be	VBZ
cord-322516-wekvet6f	49	12	localized	localize	VBN
cord-322516-wekvet6f	49	13	to	to	IN
cord-322516-wekvet6f	49	14	the	the	DT
cord-322516-wekvet6f	49	15	CGN	CGN	NNP
cord-322516-wekvet6f	49	16	in	in	IN
cord-322516-wekvet6f	49	17	several	several	JJ
cord-322516-wekvet6f	49	18	cell	cell	NN
cord-322516-wekvet6f	49	19	types	type	NNS
cord-322516-wekvet6f	49	20	,	,	,
cord-322516-wekvet6f	49	21	and	and	CC
cord-322516-wekvet6f	49	22	its	-PRON-	PRP$
cord-322516-wekvet6f	49	23	localization	localization	NN
cord-322516-wekvet6f	49	24	presumably	presumably	RB
cord-322516-wekvet6f	49	25	overlaps	overlap	VBZ
cord-322516-wekvet6f	49	26	with	with	IN
cord-322516-wekvet6f	49	27	that	that	DT
cord-322516-wekvet6f	49	28	of	of	IN
cord-322516-wekvet6f	49	29	SM	SM	NNP
cord-322516-wekvet6f	49	30	and	and	CC
cord-322516-wekvet6f	49	31	GlcCer	GlcCer	NNP
cord-322516-wekvet6f	49	32	synthase	synthase	NN
cord-322516-wekvet6f	49	33	activities	activity	NNS
cord-322516-wekvet6f	49	34	.	.	.
cord-322516-wekvet6f	50	1	This	this	DT
cord-322516-wekvet6f	50	2	led	lead	VBD
cord-322516-wekvet6f	50	3	us	-PRON-	PRP
cord-322516-wekvet6f	50	4	to	to	TO
cord-322516-wekvet6f	50	5	speculate	speculate	VB
cord-322516-wekvet6f	50	6	that	that	IN
cord-322516-wekvet6f	50	7	there	there	EX
cord-322516-wekvet6f	50	8	may	may	MD
cord-322516-wekvet6f	50	9	be	be	VB
cord-322516-wekvet6f	50	10	a	a	DT
cord-322516-wekvet6f	50	11	link	link	NN
cord-322516-wekvet6f	50	12	between	between	IN
cord-322516-wekvet6f	50	13	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	50	14	synthesis	synthesis	NN
cord-322516-wekvet6f	50	15	and	and	CC
cord-322516-wekvet6f	50	16	the	the	DT
cord-322516-wekvet6f	50	17	localization	localization	NN
cord-322516-wekvet6f	50	18	of	of	IN
cord-322516-wekvet6f	50	19	IBV	IBV	NNP
cord-322516-wekvet6f	50	20	M.	M.	NNP
cord-322516-wekvet6f	51	1	To	to	TO
cord-322516-wekvet6f	51	2	address	address	VB
cord-322516-wekvet6f	51	3	this	this	DT
cord-322516-wekvet6f	51	4	question	question	NN
cord-322516-wekvet6f	51	5	we	-PRON-	PRP
cord-322516-wekvet6f	51	6	tested	test	VBD
cord-322516-wekvet6f	51	7	the	the	DT
cord-322516-wekvet6f	51	8	effects	effect	NNS
cord-322516-wekvet6f	51	9	of	of	IN
cord-322516-wekvet6f	51	10	three	three	CD
cord-322516-wekvet6f	51	11	sphingolipid	sphingolipid	NNP
cord-322516-wekvet6f	51	12	synthesis	synthesis	NN
cord-322516-wekvet6f	51	13	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	51	14	on	on	IN
cord-322516-wekvet6f	51	15	the	the	DT
cord-322516-wekvet6f	51	16	steady	steady	JJ
cord-322516-wekvet6f	51	17	-	-	HYPH
cord-322516-wekvet6f	51	18	state	state	NN
cord-322516-wekvet6f	51	19	localization	localization	NN
cord-322516-wekvet6f	51	20	of	of	IN
cord-322516-wekvet6f	51	21	IBV	IBV	NNP
cord-322516-wekvet6f	51	22	M.	M.	NNP
cord-322516-wekvet6f	52	1	We	-PRON-	PRP
cord-322516-wekvet6f	52	2	observed	observe	VBD
cord-322516-wekvet6f	52	3	a	a	DT
cord-322516-wekvet6f	52	4	dramatic	dramatic	JJ
cord-322516-wekvet6f	52	5	redistribution	redistribution	NN
cord-322516-wekvet6f	52	6	of	of	IN
cord-322516-wekvet6f	52	7	IBV	IBV	NNP
cord-322516-wekvet6f	52	8	M	M	NNP
cord-322516-wekvet6f	52	9	induced	induce	VBN
cord-322516-wekvet6f	52	10	by	by	IN
cord-322516-wekvet6f	52	11	one	one	CD
cord-322516-wekvet6f	52	12	of	of	IN
cord-322516-wekvet6f	52	13	these	these	DT
cord-322516-wekvet6f	52	14	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	52	15	,	,	,
cord-322516-wekvet6f	52	16	the	the	DT
cord-322516-wekvet6f	52	17	glucosylceramide	glucosylceramide	NNP
cord-322516-wekvet6f	52	18	analogue	analogue	NNP
cord-322516-wekvet6f	52	19	d	d	NNP
cord-322516-wekvet6f	52	20	,	,	,
cord-322516-wekvet6f	52	21	l	l	NN
cord-322516-wekvet6f	52	22	-	-	HYPH
cord-322516-wekvet6f	52	23	threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol	threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol	JJ
cord-322516-wekvet6f	52	24	(	(	-LRB-
cord-322516-wekvet6f	52	25	PDMP	PDMP	NNP
cord-322516-wekvet6f	52	26	)	)	-RRB-
cord-322516-wekvet6f	52	27	.	.	.
cord-322516-wekvet6f	53	1	Use	use	NN
cord-322516-wekvet6f	53	2	of	of	IN
cord-322516-wekvet6f	53	3	upstream	upstream	JJ
cord-322516-wekvet6f	53	4	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	53	5	coupled	couple	VBN
cord-322516-wekvet6f	53	6	with	with	IN
cord-322516-wekvet6f	53	7	lipid	lipid	NN
cord-322516-wekvet6f	53	8	analysis	analysis	NN
cord-322516-wekvet6f	53	9	suggested	suggest	VBD
cord-322516-wekvet6f	53	10	that	that	IN
cord-322516-wekvet6f	53	11	the	the	DT
cord-322516-wekvet6f	53	12	PDMP	PDMP	NNP
cord-322516-wekvet6f	53	13	effects	effect	NNS
cord-322516-wekvet6f	53	14	are	be	VBP
cord-322516-wekvet6f	53	15	mediated	mediate	VBN
cord-322516-wekvet6f	53	16	by	by	IN
cord-322516-wekvet6f	53	17	the	the	DT
cord-322516-wekvet6f	53	18	accumulation	accumulation	NN
cord-322516-wekvet6f	53	19	of	of	IN
cord-322516-wekvet6f	53	20	the	the	DT
cord-322516-wekvet6f	53	21	precursor	precursor	NN
cord-322516-wekvet6f	53	22	ceramide	ceramide	NN
cord-322516-wekvet6f	53	23	.	.	.
cord-322516-wekvet6f	54	1	Because	because	IN
cord-322516-wekvet6f	54	2	IBV	IBV	NNP
cord-322516-wekvet6f	54	3	M	M	NNP
cord-322516-wekvet6f	54	4	can	can	MD
cord-322516-wekvet6f	54	5	be	be	VB
cord-322516-wekvet6f	54	6	induced	induce	VBN
cord-322516-wekvet6f	54	7	to	to	TO
cord-322516-wekvet6f	54	8	move	move	VB
cord-322516-wekvet6f	54	9	to	to	IN
cord-322516-wekvet6f	54	10	the	the	DT
cord-322516-wekvet6f	54	11	ER	ER	NNP
cord-322516-wekvet6f	54	12	,	,	,
cord-322516-wekvet6f	54	13	we	-PRON-	PRP
cord-322516-wekvet6f	54	14	propose	propose	VBP
cord-322516-wekvet6f	54	15	that	that	IN
cord-322516-wekvet6f	54	16	IBV	IBV	NNP
cord-322516-wekvet6f	54	17	M	M	NNP
cord-322516-wekvet6f	54	18	is	be	VBZ
cord-322516-wekvet6f	54	19	at	at	IN
cord-322516-wekvet6f	54	20	least	least	JJS
cord-322516-wekvet6f	54	21	in	in	IN
cord-322516-wekvet6f	54	22	part	part	NN
cord-322516-wekvet6f	54	23	localized	localize	VBN
cord-322516-wekvet6f	54	24	by	by	IN
cord-322516-wekvet6f	54	25	retrieval	retrieval	NN
cord-322516-wekvet6f	54	26	mechanisms	mechanism	NNS
cord-322516-wekvet6f	54	27	.	.	.
cord-322516-wekvet6f	55	1	FCS	FCS	NNP
cord-322516-wekvet6f	55	2	was	be	VBD
cord-322516-wekvet6f	55	3	from	from	IN
cord-322516-wekvet6f	55	4	Atlanta	Atlanta	NNP
cord-322516-wekvet6f	55	5	Biologicals	Biologicals	NNP
cord-322516-wekvet6f	55	6	(	(	-LRB-
cord-322516-wekvet6f	55	7	Norcross	Norcross	NNP
cord-322516-wekvet6f	55	8	,	,	,
cord-322516-wekvet6f	55	9	GA	GA	NNP
cord-322516-wekvet6f	55	10	)	)	-RRB-
cord-322516-wekvet6f	55	11	;	;	:
cord-322516-wekvet6f	55	12	fumonisin	fumonisin	NNP
cord-322516-wekvet6f	55	13	B1	B1	NNP
cord-322516-wekvet6f	55	14	was	be	VBD
cord-322516-wekvet6f	55	15	from	from	IN
cord-322516-wekvet6f	55	16	Calbiochem	Calbiochem	NNP
cord-322516-wekvet6f	55	17	(	(	-LRB-
cord-322516-wekvet6f	55	18	La	La	NNP
cord-322516-wekvet6f	55	19	Jolla	Jolla	NNP
cord-322516-wekvet6f	55	20	,	,	,
cord-322516-wekvet6f	55	21	CA	CA	NNP
cord-322516-wekvet6f	55	22	)	)	-RRB-
cord-322516-wekvet6f	55	23	;	;	:
cord-322516-wekvet6f	55	24	chromatography	chromatography	NN
cord-322516-wekvet6f	55	25	plates	plate	NNS
cord-322516-wekvet6f	55	26	were	be	VBD
cord-322516-wekvet6f	55	27	from	from	IN
cord-322516-wekvet6f	55	28	E.	E.	NNP
cord-322516-wekvet6f	55	29	Merck	Merck	NNP
cord-322516-wekvet6f	55	30	(	(	-LRB-
cord-322516-wekvet6f	55	31	Darmstadt	Darmstadt	NNP
cord-322516-wekvet6f	55	32	,	,	,
cord-322516-wekvet6f	55	33	Germany	Germany	NNP
cord-322516-wekvet6f	55	34	)	)	-RRB-
cord-322516-wekvet6f	55	35	;	;	:
cord-322516-wekvet6f	55	36	endoglycosidase	endoglycosidase	NNP
cord-322516-wekvet6f	55	37	H	H	NNP
cord-322516-wekvet6f	55	38	(	(	-LRB-
cord-322516-wekvet6f	55	39	endo	endo	NN
cord-322516-wekvet6f	55	40	H	H	NNP
cord-322516-wekvet6f	55	41	)	)	-RRB-
cord-322516-wekvet6f	55	42	from	from	IN
cord-322516-wekvet6f	55	43	New	New	NNP
cord-322516-wekvet6f	55	44	England	England	NNP
cord-322516-wekvet6f	55	45	Biolabs	Biolabs	NNP
cord-322516-wekvet6f	55	46	(	(	-LRB-
cord-322516-wekvet6f	55	47	Beverly	Beverly	NNP
cord-322516-wekvet6f	55	48	,	,	,
cord-322516-wekvet6f	55	49	MA	MA	NNP
cord-322516-wekvet6f	55	50	)	)	-RRB-
cord-322516-wekvet6f	55	51	;	;	:
cord-322516-wekvet6f	56	1	N	n	CD
cord-322516-wekvet6f	56	2	-hexanoylsphingosine	-hexanoylsphingosine	NNP
cord-322516-wekvet6f	57	1	(	(	-LRB-
cord-322516-wekvet6f	57	2	C	C	NNP
cord-322516-wekvet6f	57	3	6	6	CD
cord-322516-wekvet6f	57	4	Cer	Cer	NNP
cord-322516-wekvet6f	57	5	)	)	-RRB-
cord-322516-wekvet6f	57	6	,	,	,
cord-322516-wekvet6f	57	7	lipid	lipid	NN
cord-322516-wekvet6f	57	8	standards	standard	NNS
cord-322516-wekvet6f	57	9	,	,	,
cord-322516-wekvet6f	57	10	and	and	CC
cord-322516-wekvet6f	57	11	PDMP	PDMP	NNP
cord-322516-wekvet6f	57	12	were	be	VBD
cord-322516-wekvet6f	57	13	from	from	IN
cord-322516-wekvet6f	57	14	Matreya	Matreya	NNP
cord-322516-wekvet6f	57	15	(	(	-LRB-
cord-322516-wekvet6f	57	16	Pleasant	pleasant	JJ
cord-322516-wekvet6f	57	17	Gap	Gap	NNP
cord-322516-wekvet6f	57	18	,	,	,
cord-322516-wekvet6f	57	19	PA	PA	NNP
cord-322516-wekvet6f	57	20	)	)	-RRB-
cord-322516-wekvet6f	57	21	;	;	:
cord-322516-wekvet6f	57	22	[	[	-LRB-
cord-322516-wekvet6f	57	23	3	3	CD
cord-322516-wekvet6f	57	24	H]palmitate	H]palmitate	NNP
cord-322516-wekvet6f	57	25	(	(	-LRB-
cord-322516-wekvet6f	57	26	50	50	CD
cord-322516-wekvet6f	57	27	Ci	ci	NN
cord-322516-wekvet6f	57	28	/	/	SYM
cord-322516-wekvet6f	57	29	mmol	mmol	NN
cord-322516-wekvet6f	57	30	)	)	-RRB-
cord-322516-wekvet6f	57	31	was	be	VBD
cord-322516-wekvet6f	57	32	from	from	IN
cord-322516-wekvet6f	57	33	DuPont	DuPont	NNP
cord-322516-wekvet6f	57	34	-	-	HYPH
cord-322516-wekvet6f	57	35	NEN	NEN	NNP
cord-322516-wekvet6f	57	36	(	(	-LRB-
cord-322516-wekvet6f	57	37	Wilmington	Wilmington	NNP
cord-322516-wekvet6f	57	38	,	,	,
cord-322516-wekvet6f	57	39	DE	DE	NNP
cord-322516-wekvet6f	57	40	)	)	-RRB-
cord-322516-wekvet6f	57	41	;	;	:
cord-322516-wekvet6f	57	42	Pro	Pro	NNP
cord-322516-wekvet6f	57	43	-	-	HYPH
cord-322516-wekvet6f	57	44	Mix	mix	NN
cord-322516-wekvet6f	58	1	(	(	-LRB-
cord-322516-wekvet6f	58	2	Ͼ	ͼ	NN
cord-322516-wekvet6f	58	3	1,000	1,000	CD
cord-322516-wekvet6f	58	4	mCi	mCi	NNS
cord-322516-wekvet6f	58	5	/	/	SYM
cord-322516-wekvet6f	58	6	mmol	mmol	NN
cord-322516-wekvet6f	58	7	[	[	-LRB-
cord-322516-wekvet6f	58	8	35	35	CD
cord-322516-wekvet6f	58	9	S]methionine	S]methionine	NNP
cord-322516-wekvet6f	58	10	)	)	-RRB-
cord-322516-wekvet6f	58	11	was	be	VBD
cord-322516-wekvet6f	58	12	from	from	IN
cord-322516-wekvet6f	58	13	Amersham	Amersham	NNP
cord-322516-wekvet6f	58	14	Intl	Intl	NNP
cord-322516-wekvet6f	58	15	.	.	.
cord-322516-wekvet6f	59	1	(	(	-LRB-
cord-322516-wekvet6f	59	2	Arlington	Arlington	NNP
cord-322516-wekvet6f	59	3	Heights	Heights	NNP
cord-322516-wekvet6f	59	4	,	,	,
cord-322516-wekvet6f	59	5	IL	IL	NNP
cord-322516-wekvet6f	59	6	)	)	-RRB-
cord-322516-wekvet6f	59	7	;	;	:
cord-322516-wekvet6f	59	8	DME	DME	NNP
cord-322516-wekvet6f	59	9	,	,	,
cord-322516-wekvet6f	59	10	tissue	tissue	NN
cord-322516-wekvet6f	59	11	culture	culture	NN
cord-322516-wekvet6f	59	12	-	-	HYPH
cord-322516-wekvet6f	59	13	grade	grade	NN
cord-322516-wekvet6f	59	14	trypsin	trypsin	NN
cord-322516-wekvet6f	59	15	,	,	,
cord-322516-wekvet6f	59	16	and	and	CC
cord-322516-wekvet6f	59	17	penicillin	penicillin	NN
cord-322516-wekvet6f	59	18	-	-	HYPH
cord-322516-wekvet6f	59	19	streptomycin	streptomycin	NNS
cord-322516-wekvet6f	59	20	were	be	VBD
cord-322516-wekvet6f	59	21	from	from	IN
cord-322516-wekvet6f	59	22	GIBCO	GIBCO	NNP
cord-322516-wekvet6f	59	23	BRL	BRL	NNP
cord-322516-wekvet6f	59	24	(	(	-LRB-
cord-322516-wekvet6f	59	25	Gaithersburg	Gaithersburg	NNP
cord-322516-wekvet6f	59	26	,	,	,
cord-322516-wekvet6f	59	27	MD	MD	NNP
cord-322516-wekvet6f	59	28	)	)	-RRB-
cord-322516-wekvet6f	59	29	;	;	:
cord-322516-wekvet6f	59	30	all	all	DT
cord-322516-wekvet6f	59	31	other	other	JJ
cord-322516-wekvet6f	59	32	reagents	reagent	NNS
cord-322516-wekvet6f	59	33	were	be	VBD
cord-322516-wekvet6f	59	34	from	from	IN
cord-322516-wekvet6f	59	35	Sigma	Sigma	NNP
cord-322516-wekvet6f	59	36	Chemical	Chemical	NNP
cord-322516-wekvet6f	59	37	Co.	Co.	NNP
cord-322516-wekvet6f	59	38	(	(	-LRB-
cord-322516-wekvet6f	59	39	St.	St.	NNP
cord-322516-wekvet6f	59	40	Louis	Louis	NNP
cord-322516-wekvet6f	59	41	,	,	,
cord-322516-wekvet6f	59	42	MO	MO	NNP
cord-322516-wekvet6f	59	43	)	)	-RRB-
cord-322516-wekvet6f	59	44	.	.	.
cord-322516-wekvet6f	60	1	Antibodies	antibody	NNS
cord-322516-wekvet6f	60	2	were	be	VBD
cord-322516-wekvet6f	60	3	obtained	obtain	VBN
cord-322516-wekvet6f	60	4	as	as	IN
cord-322516-wekvet6f	60	5	follows	follow	VBZ
cord-322516-wekvet6f	60	6	:	:	:
cord-322516-wekvet6f	61	1	monoclonal	monoclonal	JJ
cord-322516-wekvet6f	61	2	anti	anti	NNP
cord-322516-wekvet6f	61	3	-	-	NNP
cord-322516-wekvet6f	61	4	Bip	Bip	NNP
cord-322516-wekvet6f	62	1	,	,	,
cord-322516-wekvet6f	62	2	Stressgen	Stressgen	NNP
cord-322516-wekvet6f	62	3	(	(	-LRB-
cord-322516-wekvet6f	62	4	Victoria	Victoria	NNP
cord-322516-wekvet6f	62	5	,	,	,
cord-322516-wekvet6f	62	6	BC	BC	NNP
cord-322516-wekvet6f	62	7	,	,	,
cord-322516-wekvet6f	62	8	Canada	Canada	NNP
cord-322516-wekvet6f	62	9	)	)	-RRB-
cord-322516-wekvet6f	62	10	;	;	,
cord-322516-wekvet6f	62	11	monoclonal	monoclonal	JJ
cord-322516-wekvet6f	62	12	anti	anti	JJ
cord-322516-wekvet6f	62	13	-	-	NN
cord-322516-wekvet6f	62	14	giantin	giantin	JJ
cord-322516-wekvet6f	63	1	and	and	CC
cord-322516-wekvet6f	63	2	monoclonal	monoclonal	JJ
cord-322516-wekvet6f	63	3	anti	anti	NNP
cord-322516-wekvet6f	63	4	-	-	NNP
cord-322516-wekvet6f	63	5	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	63	6	,	,	,
cord-322516-wekvet6f	63	7	Hans	Hans	NNP
cord-322516-wekvet6f	63	8	-	-	HYPH
cord-322516-wekvet6f	63	9	Peter	Peter	NNP
cord-322516-wekvet6f	63	10	Hauri	Hauri	NNP
cord-322516-wekvet6f	63	11	(	(	-LRB-
cord-322516-wekvet6f	63	12	Basel	Basel	NNP
cord-322516-wekvet6f	63	13	,	,	,
cord-322516-wekvet6f	63	14	Switzerland	Switzerland	NNP
cord-322516-wekvet6f	63	15	)	)	-RRB-
cord-322516-wekvet6f	63	16	;	;	:
cord-322516-wekvet6f	63	17	polyclonal	polyclonal	JJ
cord-322516-wekvet6f	63	18	anti-	anti-	NN
cord-322516-wekvet6f	63	19	␤	␤	.
cord-322516-wekvet6f	64	1	-COP	-COP	:
cord-322516-wekvet6f	64	2	,	,	,
cord-322516-wekvet6f	64	3	Jennifer	Jennifer	NNP
cord-322516-wekvet6f	64	4	Lippincott	Lippincott	NNP
cord-322516-wekvet6f	64	5	-	-	HYPH
cord-322516-wekvet6f	64	6	Schwartz	Schwartz	NNP
cord-322516-wekvet6f	64	7	(	(	-LRB-
cord-322516-wekvet6f	64	8	National	National	NNP
cord-322516-wekvet6f	64	9	Institutes	Institutes	NNPS
cord-322516-wekvet6f	64	10	of	of	IN
cord-322516-wekvet6f	64	11	Health	Health	NNP
cord-322516-wekvet6f	64	12	,	,	,
cord-322516-wekvet6f	64	13	Bethesda	Bethesda	NNP
cord-322516-wekvet6f	64	14	,	,	,
cord-322516-wekvet6f	64	15	MD	MD	NNP
cord-322516-wekvet6f	64	16	)	)	-RRB-
cord-322516-wekvet6f	64	17	;	;	,
cord-322516-wekvet6f	64	18	polyclonal	polyclonal	JJ
cord-322516-wekvet6f	65	1	␣	␣	NNP
cord-322516-wekvet6f	65	2	-mannosidase	-mannosidase	NNP
cord-322516-wekvet6f	65	3	II	II	NNP
cord-322516-wekvet6f	65	4	,	,	,
cord-322516-wekvet6f	65	5	Marilyn	Marilyn	NNP
cord-322516-wekvet6f	65	6	Farquhar	Farquhar	NNP
cord-322516-wekvet6f	65	7	(	(	-LRB-
cord-322516-wekvet6f	65	8	University	University	NNP
cord-322516-wekvet6f	65	9	of	of	IN
cord-322516-wekvet6f	65	10	California	California	NNP
cord-322516-wekvet6f	65	11	at	at	IN
cord-322516-wekvet6f	65	12	San	San	NNP
cord-322516-wekvet6f	65	13	Diego	Diego	NNP
cord-322516-wekvet6f	65	14	,	,	,
cord-322516-wekvet6f	65	15	La	La	NNP
cord-322516-wekvet6f	65	16	Jolla	Jolla	NNP
cord-322516-wekvet6f	65	17	,	,	,
cord-322516-wekvet6f	65	18	CA	CA	NNP
cord-322516-wekvet6f	65	19	)	)	-RRB-
cord-322516-wekvet6f	65	20	and	and	CC
cord-322516-wekvet6f	65	21	Kelley	Kelley	NNP
cord-322516-wekvet6f	65	22	Moreman	Moreman	NNP
cord-322516-wekvet6f	65	23	(	(	-LRB-
cord-322516-wekvet6f	65	24	University	University	NNP
cord-322516-wekvet6f	65	25	of	of	IN
cord-322516-wekvet6f	65	26	Georgia	Georgia	NNP
cord-322516-wekvet6f	65	27	,	,	,
cord-322516-wekvet6f	65	28	Athens	Athens	NNP
cord-322516-wekvet6f	65	29	,	,	,
cord-322516-wekvet6f	65	30	GA	GA	NNP
cord-322516-wekvet6f	65	31	)	)	-RRB-
cord-322516-wekvet6f	65	32	;	;	,
cord-322516-wekvet6f	65	33	polyclonal	polyclonal	JJ
cord-322516-wekvet6f	65	34	antibodies	antibody	NNS
cord-322516-wekvet6f	65	35	to	to	IN
cord-322516-wekvet6f	65	36	IBV	IBV	NNP
cord-322516-wekvet6f	65	37	M	M	NNP
cord-322516-wekvet6f	65	38	and	and	CC
cord-322516-wekvet6f	65	39	vesicular	vesicular	JJ
cord-322516-wekvet6f	65	40	stomatitis	stomatitis	NN
cord-322516-wekvet6f	65	41	virus	virus	NN
cord-322516-wekvet6f	65	42	(	(	-LRB-
cord-322516-wekvet6f	65	43	VSV	VSV	NNP
cord-322516-wekvet6f	65	44	)	)	-RRB-
cord-322516-wekvet6f	65	45	were	be	VBD
cord-322516-wekvet6f	65	46	prepared	prepare	VBN
cord-322516-wekvet6f	65	47	as	as	IN
cord-322516-wekvet6f	65	48	described	describe	VBN
cord-322516-wekvet6f	65	49	(	(	-LRB-
cord-322516-wekvet6f	65	50	Machamer	Machamer	NNP
cord-322516-wekvet6f	65	51	and	and	CC
cord-322516-wekvet6f	65	52	Rose	Rose	NNP
cord-322516-wekvet6f	65	53	,	,	,
cord-322516-wekvet6f	65	54	1987	1987	CD
cord-322516-wekvet6f	65	55	;	;	:
cord-322516-wekvet6f	65	56	Weisz	Weisz	NNP
cord-322516-wekvet6f	65	57	et	et	NNP
cord-322516-wekvet6f	65	58	al	al	NNP
cord-322516-wekvet6f	65	59	.	.	NNP
cord-322516-wekvet6f	65	60	,	,	,
cord-322516-wekvet6f	65	61	1993	1993	CD
cord-322516-wekvet6f	65	62	,	,	,
cord-322516-wekvet6f	65	63	respectively	respectively	RB
cord-322516-wekvet6f	65	64	)	)	-RRB-
cord-322516-wekvet6f	65	65	;	;	:
cord-322516-wekvet6f	65	66	Texas	Texas	NNP
cord-322516-wekvet6f	65	67	red	red	JJ
cord-322516-wekvet6f	65	68	-	-	:
cord-322516-wekvet6f	65	69	and	and	CC
cord-322516-wekvet6f	65	70	FITC	FITC	NNP
cord-322516-wekvet6f	65	71	-	-	HYPH
cord-322516-wekvet6f	65	72	conjugated	conjugate	VBN
cord-322516-wekvet6f	65	73	secondary	secondary	JJ
cord-322516-wekvet6f	65	74	antibodies	antibody	NNS
cord-322516-wekvet6f	65	75	,	,	,
cord-322516-wekvet6f	65	76	Jackson	Jackson	NNP
cord-322516-wekvet6f	65	77	ImmunoResearch	ImmunoResearch	NNP
cord-322516-wekvet6f	65	78	(	(	-LRB-
cord-322516-wekvet6f	65	79	West	West	NNP
cord-322516-wekvet6f	65	80	Grove	Grove	NNP
cord-322516-wekvet6f	65	81	,	,	,
cord-322516-wekvet6f	65	82	PA	PA	NNP
cord-322516-wekvet6f	65	83	)	)	-RRB-
cord-322516-wekvet6f	65	84	.	.	.
cord-322516-wekvet6f	66	1	Cell	cell	NN
cord-322516-wekvet6f	66	2	Culture	culture	NN
cord-322516-wekvet6f	66	3	.	.	.
cord-322516-wekvet6f	67	1	Tissue	tissue	NN
cord-322516-wekvet6f	67	2	culture	culture	NN
cord-322516-wekvet6f	67	3	cells	cell	NNS
cord-322516-wekvet6f	67	4	were	be	VBD
cord-322516-wekvet6f	67	5	grown	grow	VBN
cord-322516-wekvet6f	67	6	in	in	IN
cord-322516-wekvet6f	67	7	DME	DME	NNP
cord-322516-wekvet6f	67	8	supplemented	supplement	VBN
cord-322516-wekvet6f	67	9	with	with	IN
cord-322516-wekvet6f	67	10	5	5	CD
cord-322516-wekvet6f	67	11	%	%	NN
cord-322516-wekvet6f	67	12	(	(	-LRB-
cord-322516-wekvet6f	67	13	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	67	14	)	)	-RRB-
cord-322516-wekvet6f	67	15	or	or	CC
cord-322516-wekvet6f	67	16	10	10	CD
cord-322516-wekvet6f	67	17	%	%	NN
cord-322516-wekvet6f	67	18	(	(	-LRB-
cord-322516-wekvet6f	67	19	Vero	Vero	NNP
cord-322516-wekvet6f	67	20	)	)	-RRB-
cord-322516-wekvet6f	67	21	FCS	FCS	NNP
cord-322516-wekvet6f	67	22	.	.	.
cord-322516-wekvet6f	68	1	Cells	cell	NNS
cord-322516-wekvet6f	68	2	were	be	VBD
cord-322516-wekvet6f	68	3	grown	grow	VBN
cord-322516-wekvet6f	68	4	at	at	IN
cord-322516-wekvet6f	68	5	37	37	CD
cord-322516-wekvet6f	68	6	Њ	њ	NN
cord-322516-wekvet6f	68	7	C	c	NN
cord-322516-wekvet6f	68	8	in	in	IN
cord-322516-wekvet6f	68	9	an	an	DT
cord-322516-wekvet6f	68	10	atmosphere	atmosphere	NN
cord-322516-wekvet6f	68	11	of	of	IN
cord-322516-wekvet6f	68	12	5	5	CD
cord-322516-wekvet6f	68	13	%	%	NN
cord-322516-wekvet6f	68	14	CO	co	NN
cord-322516-wekvet6f	68	15	2	2	CD
cord-322516-wekvet6f	68	16	.	.	.
cord-322516-wekvet6f	69	1	Pulse	pulse	NN
cord-322516-wekvet6f	69	2	-	-	HYPH
cord-322516-wekvet6f	69	3	Chase	chase	NN
cord-322516-wekvet6f	69	4	Labeling	labeling	NN
cord-322516-wekvet6f	69	5	.	.	.
cord-322516-wekvet6f	70	1	Pulse	pulse	NN
cord-322516-wekvet6f	70	2	-	-	HYPH
cord-322516-wekvet6f	70	3	chase	chase	NN
cord-322516-wekvet6f	70	4	experiments	experiment	NNS
cord-322516-wekvet6f	70	5	were	be	VBD
cord-322516-wekvet6f	70	6	performed	perform	VBN
cord-322516-wekvet6f	70	7	as	as	IN
cord-322516-wekvet6f	70	8	previously	previously	RB
cord-322516-wekvet6f	70	9	described	describe	VBN
cord-322516-wekvet6f	71	1	(	(	-LRB-
cord-322516-wekvet6f	71	2	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	71	3	et	et	NNP
cord-322516-wekvet6f	71	4	al	al	NNP
cord-322516-wekvet6f	71	5	.	.	NNP
cord-322516-wekvet6f	71	6	,	,	,
cord-322516-wekvet6f	71	7	1992	1992	CD
cord-322516-wekvet6f	71	8	;	;	:
cord-322516-wekvet6f	71	9	Weisz	Weisz	NNP
cord-322516-wekvet6f	71	10	et	et	NNP
cord-322516-wekvet6f	71	11	al	al	NNP
cord-322516-wekvet6f	71	12	.	.	NNP
cord-322516-wekvet6f	71	13	,	,	,
cord-322516-wekvet6f	71	14	1993	1993	CD
cord-322516-wekvet6f	71	15	)	)	-RRB-
cord-322516-wekvet6f	71	16	.	.	.
cord-322516-wekvet6f	72	1	Briefly	briefly	RB
cord-322516-wekvet6f	72	2	,	,	,
cord-322516-wekvet6f	72	3	cells	cell	NNS
cord-322516-wekvet6f	72	4	were	be	VBD
cord-322516-wekvet6f	72	5	plated	plate	VBN
cord-322516-wekvet6f	72	6	in	in	IN
cord-322516-wekvet6f	72	7	35-mm	35-mm	CD
cord-322516-wekvet6f	72	8	dishes	dish	NNS
cord-322516-wekvet6f	72	9	the	the	DT
cord-322516-wekvet6f	72	10	night	night	NN
cord-322516-wekvet6f	72	11	before	before	IN
cord-322516-wekvet6f	72	12	the	the	DT
cord-322516-wekvet6f	72	13	experiment	experiment	NN
cord-322516-wekvet6f	72	14	to	to	TO
cord-322516-wekvet6f	72	15	be	be	VB
cord-322516-wekvet6f	72	16	90	90	CD
cord-322516-wekvet6f	72	17	%	%	NN
cord-322516-wekvet6f	72	18	confluent	confluent	JJ
cord-322516-wekvet6f	72	19	the	the	DT
cord-322516-wekvet6f	72	20	next	next	JJ
cord-322516-wekvet6f	72	21	day	day	NN
cord-322516-wekvet6f	72	22	.	.	.
cord-322516-wekvet6f	73	1	VSV	VSV	NNP
cord-322516-wekvet6f	73	2	(	(	-LRB-
cord-322516-wekvet6f	73	3	San	San	NNP
cord-322516-wekvet6f	73	4	Juan	Juan	NNP
cord-322516-wekvet6f	73	5	strain	strain	NN
cord-322516-wekvet6f	73	6	,	,	,
cord-322516-wekvet6f	73	7	Indiana	Indiana	NNP
cord-322516-wekvet6f	73	8	serotype	serotype	NN
cord-322516-wekvet6f	73	9	)	)	-RRB-
cord-322516-wekvet6f	73	10	was	be	VBD
cord-322516-wekvet6f	73	11	adsorbed	adsorb	VBN
cord-322516-wekvet6f	73	12	for	for	IN
cord-322516-wekvet6f	73	13	30	30	CD
cord-322516-wekvet6f	73	14	min	min	NN
cord-322516-wekvet6f	73	15	in	in	IN
cord-322516-wekvet6f	73	16	0.5	0.5	CD
cord-322516-wekvet6f	73	17	ml	ml	NNS
cord-322516-wekvet6f	73	18	of	of	IN
cord-322516-wekvet6f	73	19	serum	serum	NN
cord-322516-wekvet6f	73	20	-	-	HYPH
cord-322516-wekvet6f	73	21	free	free	JJ
cord-322516-wekvet6f	73	22	DME	DME	NNP
cord-322516-wekvet6f	73	23	.	.	.
cord-322516-wekvet6f	74	1	At	at	IN
cord-322516-wekvet6f	74	2	4	4	CD
cord-322516-wekvet6f	74	3	h	h	NN
cord-322516-wekvet6f	74	4	after	after	IN
cord-322516-wekvet6f	74	5	infection	infection	NN
cord-322516-wekvet6f	74	6	,	,	,
cord-322516-wekvet6f	74	7	the	the	DT
cord-322516-wekvet6f	74	8	cells	cell	NNS
cord-322516-wekvet6f	74	9	were	be	VBD
cord-322516-wekvet6f	74	10	starved	starve	VBN
cord-322516-wekvet6f	74	11	for	for	IN
cord-322516-wekvet6f	74	12	methionine	methionine	NN
cord-322516-wekvet6f	74	13	for	for	IN
cord-322516-wekvet6f	74	14	15	15	CD
cord-322516-wekvet6f	74	15	min	min	NN
cord-322516-wekvet6f	74	16	.	.	.
cord-322516-wekvet6f	75	1	Cells	cell	NNS
cord-322516-wekvet6f	75	2	were	be	VBD
cord-322516-wekvet6f	75	3	then	then	RB
cord-322516-wekvet6f	75	4	pulsed	pulse	VBN
cord-322516-wekvet6f	75	5	for	for	IN
cord-322516-wekvet6f	75	6	5	5	CD
cord-322516-wekvet6f	75	7	min	min	NN
cord-322516-wekvet6f	75	8	with	with	IN
cord-322516-wekvet6f	75	9	50	50	CD
cord-322516-wekvet6f	75	10	Ci	ci	NN
cord-322516-wekvet6f	75	11	35	35	CD
cord-322516-wekvet6f	75	12	S	S	NNP
cord-322516-wekvet6f	75	13	-	-	HYPH
cord-322516-wekvet6f	75	14	Pro	pro	JJ
cord-322516-wekvet6f	75	15	-	-	NN
cord-322516-wekvet6f	75	16	mix	mix	NN
cord-322516-wekvet6f	75	17	and	and	CC
cord-322516-wekvet6f	75	18	chased	chase	VBN
cord-322516-wekvet6f	75	19	for	for	IN
cord-322516-wekvet6f	75	20	the	the	DT
cord-322516-wekvet6f	75	21	indicated	indicate	VBN
cord-322516-wekvet6f	75	22	amount	amount	NN
cord-322516-wekvet6f	75	23	of	of	IN
cord-322516-wekvet6f	75	24	time	time	NN
cord-322516-wekvet6f	75	25	in	in	IN
cord-322516-wekvet6f	75	26	the	the	DT
cord-322516-wekvet6f	75	27	presence	presence	NN
cord-322516-wekvet6f	75	28	or	or	CC
cord-322516-wekvet6f	75	29	absence	absence	NN
cord-322516-wekvet6f	75	30	of	of	IN
cord-322516-wekvet6f	75	31	the	the	DT
cord-322516-wekvet6f	75	32	indicated	indicate	VBN
cord-322516-wekvet6f	75	33	drugs	drug	NNS
cord-322516-wekvet6f	75	34	.	.	.
cord-322516-wekvet6f	76	1	The	the	DT
cord-322516-wekvet6f	76	2	isopropanol	isopropanol	NN
cord-322516-wekvet6f	76	3	carrier	carrier	NN
cord-322516-wekvet6f	76	4	alone	alone	RB
cord-322516-wekvet6f	76	5	had	have	VBD
cord-322516-wekvet6f	76	6	no	no	DT
cord-322516-wekvet6f	76	7	effect	effect	NN
cord-322516-wekvet6f	76	8	on	on	IN
cord-322516-wekvet6f	76	9	the	the	DT
cord-322516-wekvet6f	76	10	rate	rate	NN
cord-322516-wekvet6f	76	11	of	of	IN
cord-322516-wekvet6f	76	12	transport	transport	NN
cord-322516-wekvet6f	76	13	of	of	IN
cord-322516-wekvet6f	76	14	VSV	VSV	NNP
cord-322516-wekvet6f	76	15	G	G	NNP
cord-322516-wekvet6f	76	16	protein	protein	NN
cord-322516-wekvet6f	76	17	.	.	.
cord-322516-wekvet6f	77	1	After	after	IN
cord-322516-wekvet6f	77	2	the	the	DT
cord-322516-wekvet6f	77	3	chase	chase	NN
cord-322516-wekvet6f	77	4	,	,	,
cord-322516-wekvet6f	77	5	cells	cell	NNS
cord-322516-wekvet6f	77	6	were	be	VBD
cord-322516-wekvet6f	77	7	washed	wash	VBN
cord-322516-wekvet6f	77	8	once	once	RB
cord-322516-wekvet6f	77	9	with	with	IN
cord-322516-wekvet6f	77	10	cold	cold	JJ
cord-322516-wekvet6f	77	11	PBS	PBS	NNP
cord-322516-wekvet6f	77	12	and	and	CC
cord-322516-wekvet6f	77	13	lysed	lyse	VBN
cord-322516-wekvet6f	77	14	in	in	IN
cord-322516-wekvet6f	77	15	detergent	detergent	NN
cord-322516-wekvet6f	77	16	.	.	.
cord-322516-wekvet6f	78	1	VSV	VSV	NNP
cord-322516-wekvet6f	78	2	G	G	NNP
cord-322516-wekvet6f	78	3	protein	protein	NN
cord-322516-wekvet6f	78	4	was	be	VBD
cord-322516-wekvet6f	78	5	then	then	RB
cord-322516-wekvet6f	78	6	immunoprecipitated	immunoprecipitate	VBN
cord-322516-wekvet6f	78	7	,	,	,
cord-322516-wekvet6f	78	8	treated	treat	VBN
cord-322516-wekvet6f	78	9	with	with	IN
cord-322516-wekvet6f	78	10	endo	endo	NNP
cord-322516-wekvet6f	78	11	H	H	NNP
cord-322516-wekvet6f	78	12	as	as	IN
cord-322516-wekvet6f	78	13	described	describe	VBN
cord-322516-wekvet6f	78	14	(	(	-LRB-
cord-322516-wekvet6f	78	15	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	78	16	et	et	NNP
cord-322516-wekvet6f	78	17	al	al	NNP
cord-322516-wekvet6f	78	18	.	.	NNP
cord-322516-wekvet6f	78	19	,	,	,
cord-322516-wekvet6f	78	20	1992	1992	CD
cord-322516-wekvet6f	78	21	)	)	-RRB-
cord-322516-wekvet6f	78	22	,	,	,
cord-322516-wekvet6f	78	23	separated	separate	VBN
cord-322516-wekvet6f	78	24	by	by	IN
cord-322516-wekvet6f	78	25	SDS	SDS	NNP
cord-322516-wekvet6f	78	26	-	-	HYPH
cord-322516-wekvet6f	78	27	PAGE	PAGE	NNP
cord-322516-wekvet6f	78	28	,	,	,
cord-322516-wekvet6f	78	29	and	and	CC
cord-322516-wekvet6f	78	30	visu	visu	NN
cord-322516-wekvet6f	78	31	-	-	HYPH
cord-322516-wekvet6f	78	32	alized	alize	VBN
cord-322516-wekvet6f	78	33	by	by	IN
cord-322516-wekvet6f	78	34	fluorography	fluorography	NNP
cord-322516-wekvet6f	78	35	.	.	.
cord-322516-wekvet6f	79	1	Endo	Endo	NNP
cord-322516-wekvet6f	79	2	H	H	NNP
cord-322516-wekvet6f	79	3	-	-	HYPH
cord-322516-wekvet6f	79	4	sensitive	sensitive	JJ
cord-322516-wekvet6f	79	5	and	and	CC
cord-322516-wekvet6f	79	6	-resistant	-resistant	JJ
cord-322516-wekvet6f	79	7	forms	form	NNS
cord-322516-wekvet6f	79	8	of	of	IN
cord-322516-wekvet6f	79	9	the	the	DT
cord-322516-wekvet6f	79	10	VSV	VSV	NNP
cord-322516-wekvet6f	79	11	G	G	NNP
cord-322516-wekvet6f	79	12	protein	protein	NN
cord-322516-wekvet6f	79	13	were	be	VBD
cord-322516-wekvet6f	79	14	quantitated	quantitate	VBN
cord-322516-wekvet6f	79	15	by	by	IN
cord-322516-wekvet6f	79	16	densitometry	densitometry	NNP
cord-322516-wekvet6f	79	17	.	.	.
cord-322516-wekvet6f	80	1	Indirect	Indirect	NNP
cord-322516-wekvet6f	80	2	Immunofluorescence	Immunofluorescence	NNP
cord-322516-wekvet6f	80	3	Microscopy	Microscopy	NNP
cord-322516-wekvet6f	80	4	.	.	.
cord-322516-wekvet6f	81	1	These	these	DT
cord-322516-wekvet6f	81	2	experiments	experiment	NNS
cord-322516-wekvet6f	81	3	were	be	VBD
cord-322516-wekvet6f	81	4	performed	perform	VBN
cord-322516-wekvet6f	81	5	as	as	IN
cord-322516-wekvet6f	81	6	previously	previously	RB
cord-322516-wekvet6f	81	7	described	describe	VBN
cord-322516-wekvet6f	81	8	(	(	-LRB-
cord-322516-wekvet6f	81	9	Swift	Swift	NNP
cord-322516-wekvet6f	81	10	and	and	CC
cord-322516-wekvet6f	81	11	Machamer	Machamer	NNP
cord-322516-wekvet6f	81	12	,	,	,
cord-322516-wekvet6f	81	13	1991	1991	CD
cord-322516-wekvet6f	81	14	)	)	-RRB-
cord-322516-wekvet6f	81	15	.	.	.
cord-322516-wekvet6f	82	1	Briefly	briefly	RB
cord-322516-wekvet6f	82	2	,	,	,
cord-322516-wekvet6f	82	3	cells	cell	NNS
cord-322516-wekvet6f	82	4	were	be	VBD
cord-322516-wekvet6f	82	5	infected	infect	VBN
cord-322516-wekvet6f	82	6	for	for	IN
cord-322516-wekvet6f	82	7	30	30	CD
cord-322516-wekvet6f	82	8	min	min	NN
cord-322516-wekvet6f	82	9	with	with	IN
cord-322516-wekvet6f	82	10	a	a	DT
cord-322516-wekvet6f	82	11	recombinant	recombinant	JJ
cord-322516-wekvet6f	82	12	vaccinia	vaccinia	NN
cord-322516-wekvet6f	82	13	virus	virus	NN
cord-322516-wekvet6f	82	14	encoding	encode	VBG
cord-322516-wekvet6f	82	15	IBV	IBV	NNP
cord-322516-wekvet6f	82	16	M	M	NNP
cord-322516-wekvet6f	82	17	,	,	,
cord-322516-wekvet6f	82	18	and	and	CC
cord-322516-wekvet6f	82	19	the	the	DT
cord-322516-wekvet6f	82	20	indicated	indicate	VBN
cord-322516-wekvet6f	82	21	treatments	treatment	NNS
cord-322516-wekvet6f	82	22	were	be	VBD
cord-322516-wekvet6f	82	23	begun	begin	VBN
cord-322516-wekvet6f	82	24	4	4	CD
cord-322516-wekvet6f	82	25	h	h	NN
cord-322516-wekvet6f	82	26	after	after	IN
cord-322516-wekvet6f	82	27	infection	infection	NN
cord-322516-wekvet6f	82	28	.	.	.
cord-322516-wekvet6f	83	1	For	for	IN
cord-322516-wekvet6f	83	2	experiments	experiment	NNS
cord-322516-wekvet6f	83	3	using	use	VBG
cord-322516-wekvet6f	83	4	exogenous	exogenous	JJ
cord-322516-wekvet6f	83	5	ceramides	ceramide	NNS
cord-322516-wekvet6f	83	6	,	,	,
cord-322516-wekvet6f	83	7	the	the	DT
cord-322516-wekvet6f	83	8	soluble	soluble	JJ
cord-322516-wekvet6f	83	9	short	short	JJ
cord-322516-wekvet6f	83	10	-	-	HYPH
cord-322516-wekvet6f	83	11	chain	chain	NN
cord-322516-wekvet6f	83	12	analogues	analogue	NNS
cord-322516-wekvet6f	83	13	of	of	IN
cord-322516-wekvet6f	83	14	ceramide	ceramide	NN
cord-322516-wekvet6f	83	15	were	be	VBD
cord-322516-wekvet6f	83	16	added	add	VBN
cord-322516-wekvet6f	83	17	to	to	IN
cord-322516-wekvet6f	83	18	cells	cell	NNS
cord-322516-wekvet6f	83	19	as	as	IN
cord-322516-wekvet6f	83	20	a	a	DT
cord-322516-wekvet6f	83	21	complex	complex	NN
cord-322516-wekvet6f	83	22	with	with	IN
cord-322516-wekvet6f	83	23	0.34	0.34	CD
cord-322516-wekvet6f	83	24	mg	mg	NNP
cord-322516-wekvet6f	83	25	/	/	SYM
cord-322516-wekvet6f	83	26	ml	ml	NN
cord-322516-wekvet6f	83	27	defatted	defatte	VBD
cord-322516-wekvet6f	83	28	BSA	BSA	NNP
cord-322516-wekvet6f	83	29	as	as	IN
cord-322516-wekvet6f	83	30	described	describe	VBN
cord-322516-wekvet6f	83	31	(	(	-LRB-
cord-322516-wekvet6f	83	32	Pagano	Pagano	NNP
cord-322516-wekvet6f	83	33	and	and	CC
cord-322516-wekvet6f	83	34	Martin	Martin	NNP
cord-322516-wekvet6f	83	35	,	,	,
cord-322516-wekvet6f	83	36	1988	1988	CD
cord-322516-wekvet6f	83	37	)	)	-RRB-
cord-322516-wekvet6f	83	38	.	.	.
cord-322516-wekvet6f	84	1	After	after	IN
cord-322516-wekvet6f	84	2	treatment	treatment	NN
cord-322516-wekvet6f	84	3	,	,	,
cord-322516-wekvet6f	84	4	cells	cell	NNS
cord-322516-wekvet6f	84	5	were	be	VBD
cord-322516-wekvet6f	84	6	fixed	fix	VBN
cord-322516-wekvet6f	84	7	,	,	,
cord-322516-wekvet6f	84	8	permeabilized	permeabilized	JJ
cord-322516-wekvet6f	84	9	,	,	,
cord-322516-wekvet6f	84	10	and	and	CC
cord-322516-wekvet6f	84	11	stained	stain	VBN
cord-322516-wekvet6f	84	12	with	with	IN
cord-322516-wekvet6f	84	13	the	the	DT
cord-322516-wekvet6f	84	14	appropriate	appropriate	JJ
cord-322516-wekvet6f	84	15	antibody	antibody	NN
cord-322516-wekvet6f	84	16	.	.	.
cord-322516-wekvet6f	85	1	Images	image	NNS
cord-322516-wekvet6f	85	2	were	be	VBD
cord-322516-wekvet6f	85	3	acquired	acquire	VBN
cord-322516-wekvet6f	85	4	using	use	VBG
cord-322516-wekvet6f	85	5	a	a	DT
cord-322516-wekvet6f	85	6	microscope	microscope	NN
cord-322516-wekvet6f	85	7	(	(	-LRB-
cord-322516-wekvet6f	85	8	Axioskop	Axioskop	NNP
cord-322516-wekvet6f	85	9	;	;	:
cord-322516-wekvet6f	85	10	Zeiss	Zeiss	NNP
cord-322516-wekvet6f	85	11	,	,	,
cord-322516-wekvet6f	85	12	Inc.	Inc.	NNP
cord-322516-wekvet6f	85	13	,	,	,
cord-322516-wekvet6f	85	14	Thornwood	Thornwood	NNP
cord-322516-wekvet6f	85	15	,	,	,
cord-322516-wekvet6f	85	16	NY	NY	NNP
cord-322516-wekvet6f	85	17	)	)	-RRB-
cord-322516-wekvet6f	85	18	equipped	equip	VBN
cord-322516-wekvet6f	85	19	with	with	IN
cord-322516-wekvet6f	85	20	epifluorescence	epifluorescence	NN
cord-322516-wekvet6f	85	21	and	and	CC
cord-322516-wekvet6f	85	22	a	a	DT
cord-322516-wekvet6f	85	23	CCD	ccd	NN
cord-322516-wekvet6f	85	24	camera	camera	NN
cord-322516-wekvet6f	86	1	(	(	-LRB-
cord-322516-wekvet6f	86	2	Photometrics	Photometrics	NNP
cord-322516-wekvet6f	86	3	Sensys	Sensys	NNP
cord-322516-wekvet6f	86	4	,	,	,
cord-322516-wekvet6f	86	5	Tucson	Tucson	NNP
cord-322516-wekvet6f	86	6	,	,	,
cord-322516-wekvet6f	86	7	AZ	AZ	NNP
cord-322516-wekvet6f	86	8	)	)	-RRB-
cord-322516-wekvet6f	86	9	using	use	VBG
cord-322516-wekvet6f	86	10	IP	IP	NNP
cord-322516-wekvet6f	86	11	Lab	Lab	NNP
cord-322516-wekvet6f	86	12	software	software	NN
cord-322516-wekvet6f	86	13	(	(	-LRB-
cord-322516-wekvet6f	86	14	Signal	Signal	NNP
cord-322516-wekvet6f	86	15	Analytics	Analytics	NNP
cord-322516-wekvet6f	86	16	Corp.	Corp.	NNP
cord-322516-wekvet6f	86	17	,	,	,
cord-322516-wekvet6f	86	18	Vienna	Vienna	NNP
cord-322516-wekvet6f	86	19	,	,	,
cord-322516-wekvet6f	86	20	VA	VA	NNP
cord-322516-wekvet6f	86	21	)	)	-RRB-
cord-322516-wekvet6f	86	22	.	.	.
cord-322516-wekvet6f	87	1	All	all	DT
cord-322516-wekvet6f	87	2	images	image	NNS
cord-322516-wekvet6f	87	3	shown	show	VBN
cord-322516-wekvet6f	87	4	are	be	VBP
cord-322516-wekvet6f	87	5	the	the	DT
cord-322516-wekvet6f	87	6	raw	raw	JJ
cord-322516-wekvet6f	87	7	data	datum	NNS
cord-322516-wekvet6f	87	8	collected	collect	VBN
cord-322516-wekvet6f	87	9	at	at	IN
cord-322516-wekvet6f	87	10	1	1	CD
cord-322516-wekvet6f	87	11	ϫ	ϫ	CD
cord-322516-wekvet6f	87	12	1	1	CD
cord-322516-wekvet6f	87	13	binning	binning	NN
cord-322516-wekvet6f	87	14	with	with	IN
cord-322516-wekvet6f	87	15	a	a	DT
cord-322516-wekvet6f	87	16	gain	gain	NN
cord-322516-wekvet6f	87	17	of	of	IN
cord-322516-wekvet6f	87	18	1	1	CD
cord-322516-wekvet6f	87	19	.	.	.
cord-322516-wekvet6f	88	1	Lipid	Lipid	NNP
cord-322516-wekvet6f	88	2	Synthesis	Synthesis	NNP
cord-322516-wekvet6f	88	3	Assays	Assays	NNPS
cord-322516-wekvet6f	88	4	.	.	.
cord-322516-wekvet6f	89	1	Cells	cell	NNS
cord-322516-wekvet6f	89	2	were	be	VBD
cord-322516-wekvet6f	89	3	seeded	seed	VBN
cord-322516-wekvet6f	89	4	onto	onto	IN
cord-322516-wekvet6f	89	5	6-cm	6-cm	CD
cord-322516-wekvet6f	89	6	plastic	plastic	JJ
cord-322516-wekvet6f	89	7	dishes	dish	NNS
cord-322516-wekvet6f	89	8	2	2	CD
cord-322516-wekvet6f	89	9	d	d	NN
cord-322516-wekvet6f	89	10	before	before	IN
cord-322516-wekvet6f	89	11	the	the	DT
cord-322516-wekvet6f	89	12	experiment	experiment	NN
cord-322516-wekvet6f	89	13	so	so	IN
cord-322516-wekvet6f	89	14	that	that	IN
cord-322516-wekvet6f	89	15	they	-PRON-	PRP
cord-322516-wekvet6f	89	16	were	be	VBD
cord-322516-wekvet6f	89	17	90	90	CD
cord-322516-wekvet6f	89	18	%	%	NN
cord-322516-wekvet6f	89	19	confluent	confluent	JJ
cord-322516-wekvet6f	89	20	the	the	DT
cord-322516-wekvet6f	89	21	day	day	NN
cord-322516-wekvet6f	89	22	of	of	IN
cord-322516-wekvet6f	89	23	the	the	DT
cord-322516-wekvet6f	89	24	experiment	experiment	NN
cord-322516-wekvet6f	89	25	.	.	.
cord-322516-wekvet6f	90	1	Cells	cell	NNS
cord-322516-wekvet6f	90	2	were	be	VBD
cord-322516-wekvet6f	90	3	incubated	incubate	VBN
cord-322516-wekvet6f	90	4	in	in	IN
cord-322516-wekvet6f	90	5	DME	DME	NNP
cord-322516-wekvet6f	90	6	supplemented	supplement	VBN
cord-322516-wekvet6f	90	7	with	with	IN
cord-322516-wekvet6f	90	8	50	50	CD
cord-322516-wekvet6f	90	9	g	g	NN
cord-322516-wekvet6f	90	10	/	/	SYM
cord-322516-wekvet6f	90	11	ml	ml	NN
cord-322516-wekvet6f	90	12	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	90	13	,	,	,
cord-322516-wekvet6f	90	14	and	and	CC
cord-322516-wekvet6f	90	15	half	half	NN
cord-322516-wekvet6f	90	16	of	of	IN
cord-322516-wekvet6f	90	17	the	the	DT
cord-322516-wekvet6f	90	18	dishes	dish	NNS
cord-322516-wekvet6f	90	19	were	be	VBD
cord-322516-wekvet6f	90	20	also	also	RB
cord-322516-wekvet6f	90	21	incubated	incubate	VBN
cord-322516-wekvet6f	90	22	with	with	IN
cord-322516-wekvet6f	90	23	5	5	CD
cord-322516-wekvet6f	90	24	mM	mm	NN
cord-322516-wekvet6f	90	25	␤	␤	NNP
cord-322516-wekvet6f	90	26	CA	CA	NNP
cord-322516-wekvet6f	90	27	.	.	.
cord-322516-wekvet6f	91	1	1	1	CD
cord-322516-wekvet6f	91	2	h	h	NN
cord-322516-wekvet6f	91	3	later	later	RB
cord-322516-wekvet6f	91	4	,	,	,
cord-322516-wekvet6f	91	5	fresh	fresh	JJ
cord-322516-wekvet6f	91	6	medium	medium	NN
cord-322516-wekvet6f	91	7	containing	contain	VBG
cord-322516-wekvet6f	91	8	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	91	9	and	and	CC
cord-322516-wekvet6f	91	10	[	[	-LRB-
cord-322516-wekvet6f	91	11	3	3	CD
cord-322516-wekvet6f	91	12	H]palmitate	H]palmitate	NNP
cord-322516-wekvet6f	91	13	(	(	-LRB-
cord-322516-wekvet6f	91	14	100	100	CD
cord-322516-wekvet6f	91	15	Ci/	Ci/	NNP
cord-322516-wekvet6f	91	16	dish	dish	NN
cord-322516-wekvet6f	91	17	)	)	-RRB-
cord-322516-wekvet6f	91	18	was	be	VBD
cord-322516-wekvet6f	91	19	added	add	VBN
cord-322516-wekvet6f	91	20	,	,	,
cord-322516-wekvet6f	91	21	along	along	IN
cord-322516-wekvet6f	91	22	with	with	IN
cord-322516-wekvet6f	91	23	either	either	DT
cord-322516-wekvet6f	91	24	1	1	CD
cord-322516-wekvet6f	91	25	%	%	NN
cord-322516-wekvet6f	91	26	isopropanol	isopropanol	NN
cord-322516-wekvet6f	91	27	(	(	-LRB-
cord-322516-wekvet6f	91	28	control	control	NN
cord-322516-wekvet6f	91	29	and	and	CC
cord-322516-wekvet6f	91	30	␤	␤	NNP
cord-322516-wekvet6f	91	31	CA	CA	NNP
cord-322516-wekvet6f	91	32	)	)	-RRB-
cord-322516-wekvet6f	91	33	or	or	CC
cord-322516-wekvet6f	91	34	100	100	CD
cord-322516-wekvet6f	91	35	M	M	NNP
cord-322516-wekvet6f	91	36	PDMP	PDMP	NNP
cord-322516-wekvet6f	91	37	and	and	CC
cord-322516-wekvet6f	91	38	5	5	CD
cord-322516-wekvet6f	91	39	mM	mm	CD
cord-322516-wekvet6f	91	40	␤	␤	NNP
cord-322516-wekvet6f	91	41	CA	CA	NNP
cord-322516-wekvet6f	91	42	if	if	IN
cord-322516-wekvet6f	91	43	indicated	indicate	VBN
cord-322516-wekvet6f	91	44	.	.	.
cord-322516-wekvet6f	92	1	1	1	CD
cord-322516-wekvet6f	92	2	h	h	NN
cord-322516-wekvet6f	92	3	later	later	RB
cord-322516-wekvet6f	92	4	,	,	,
cord-322516-wekvet6f	92	5	cells	cell	NNS
cord-322516-wekvet6f	92	6	were	be	VBD
cord-322516-wekvet6f	92	7	trypsinized	trypsinize	VBN
cord-322516-wekvet6f	92	8	and	and	CC
cord-322516-wekvet6f	92	9	washed	wash	VBD
cord-322516-wekvet6f	92	10	off	off	RP
cord-322516-wekvet6f	92	11	the	the	DT
cord-322516-wekvet6f	92	12	plate	plate	NN
cord-322516-wekvet6f	92	13	in	in	IN
cord-322516-wekvet6f	92	14	0.8	0.8	CD
cord-322516-wekvet6f	92	15	ml	ml	NN
cord-322516-wekvet6f	92	16	cold	cold	JJ
cord-322516-wekvet6f	92	17	PBS	PBS	NNP
cord-322516-wekvet6f	92	18	.	.	.
cord-322516-wekvet6f	93	1	To	to	TO
cord-322516-wekvet6f	93	2	normalize	normalize	VB
cord-322516-wekvet6f	93	3	lipid	lipid	NN
cord-322516-wekvet6f	93	4	levels	level	NNS
cord-322516-wekvet6f	93	5	,	,	,
cord-322516-wekvet6f	93	6	50	50	CD
cord-322516-wekvet6f	93	7	l	l	NNS
cord-322516-wekvet6f	93	8	were	be	VBD
cord-322516-wekvet6f	93	9	removed	remove	VBN
cord-322516-wekvet6f	93	10	for	for	IN
cord-322516-wekvet6f	93	11	a	a	DT
cord-322516-wekvet6f	93	12	protein	protein	NN
cord-322516-wekvet6f	93	13	assay	assay	NN
cord-322516-wekvet6f	93	14	by	by	IN
cord-322516-wekvet6f	93	15	the	the	DT
cord-322516-wekvet6f	93	16	method	method	NN
cord-322516-wekvet6f	93	17	of	of	IN
cord-322516-wekvet6f	93	18	Bradford	Bradford	NNP
cord-322516-wekvet6f	93	19	(	(	-LRB-
cord-322516-wekvet6f	93	20	1976	1976	CD
cord-322516-wekvet6f	93	21	)	)	-RRB-
cord-322516-wekvet6f	93	22	.	.	.
cord-322516-wekvet6f	94	1	Lipids	lipid	NNS
cord-322516-wekvet6f	94	2	were	be	VBD
cord-322516-wekvet6f	94	3	then	then	RB
cord-322516-wekvet6f	94	4	extracted	extract	VBN
cord-322516-wekvet6f	94	5	by	by	IN
cord-322516-wekvet6f	94	6	the	the	DT
cord-322516-wekvet6f	94	7	method	method	NN
cord-322516-wekvet6f	94	8	of	of	IN
cord-322516-wekvet6f	94	9	Bligh	Bligh	NNP
cord-322516-wekvet6f	94	10	and	and	CC
cord-322516-wekvet6f	94	11	Dyer	Dyer	NNP
cord-322516-wekvet6f	94	12	(	(	-LRB-
cord-322516-wekvet6f	94	13	1959	1959	CD
cord-322516-wekvet6f	94	14	)	)	-RRB-
cord-322516-wekvet6f	94	15	.	.	.
cord-322516-wekvet6f	95	1	Labeled	label	VBN
cord-322516-wekvet6f	95	2	samples	sample	NNS
cord-322516-wekvet6f	95	3	were	be	VBD
cord-322516-wekvet6f	95	4	doped	dope	VBN
cord-322516-wekvet6f	95	5	with	with	IN
cord-322516-wekvet6f	95	6	10	10	CD
cord-322516-wekvet6f	95	7	g	g	NN
cord-322516-wekvet6f	95	8	cold	cold	JJ
cord-322516-wekvet6f	95	9	ceramide	ceramide	NN
cord-322516-wekvet6f	95	10	to	to	TO
cord-322516-wekvet6f	95	11	allow	allow	VB
cord-322516-wekvet6f	95	12	for	for	IN
cord-322516-wekvet6f	95	13	visualization	visualization	NN
cord-322516-wekvet6f	95	14	.	.	.
cord-322516-wekvet6f	96	1	Samples	sample	NNS
cord-322516-wekvet6f	96	2	were	be	VBD
cord-322516-wekvet6f	96	3	run	run	VBN
cord-322516-wekvet6f	96	4	on	on	IN
cord-322516-wekvet6f	96	5	10	10	CD
cord-322516-wekvet6f	96	6	ϫ	ϫ	CD
cord-322516-wekvet6f	96	7	10	10	CD
cord-322516-wekvet6f	96	8	cm	cm	NN
cord-322516-wekvet6f	96	9	high	high	JJ
cord-322516-wekvet6f	96	10	performance	performance	NN
cord-322516-wekvet6f	96	11	thinlayer	thinlayer	NN
cord-322516-wekvet6f	96	12	chromatography	chromatography	NN
cord-322516-wekvet6f	96	13	plates	plate	NNS
cord-322516-wekvet6f	96	14	with	with	IN
cord-322516-wekvet6f	96	15	a	a	DT
cord-322516-wekvet6f	96	16	mobile	mobile	JJ
cord-322516-wekvet6f	96	17	phase	phase	NN
cord-322516-wekvet6f	96	18	of	of	IN
cord-322516-wekvet6f	96	19	chloroform	chloroform	NN
cord-322516-wekvet6f	96	20	/	/	SYM
cord-322516-wekvet6f	96	21	glacial	glacial	JJ
cord-322516-wekvet6f	96	22	acetic	acetic	JJ
cord-322516-wekvet6f	96	23	acid	acid	NN
cord-322516-wekvet6f	96	24	(	(	-LRB-
cord-322516-wekvet6f	96	25	9:1	9:1	CD
cord-322516-wekvet6f	96	26	;	;	:
cord-322516-wekvet6f	96	27	Abe	Abe	NNP
cord-322516-wekvet6f	96	28	et	et	NNP
cord-322516-wekvet6f	96	29	al	al	NNP
cord-322516-wekvet6f	96	30	.	.	NNP
cord-322516-wekvet6f	96	31	,	,	,
cord-322516-wekvet6f	96	32	1992	1992	CD
cord-322516-wekvet6f	96	33	)	)	-RRB-
cord-322516-wekvet6f	96	34	.	.	.
cord-322516-wekvet6f	97	1	Plates	plate	NNS
cord-322516-wekvet6f	97	2	were	be	VBD
cord-322516-wekvet6f	97	3	sprayed	spray	VBN
cord-322516-wekvet6f	97	4	with	with	IN
cord-322516-wekvet6f	97	5	water	water	NN
cord-322516-wekvet6f	97	6	to	to	TO
cord-322516-wekvet6f	97	7	visualize	visualize	VB
cord-322516-wekvet6f	97	8	the	the	DT
cord-322516-wekvet6f	97	9	ceramide	ceramide	NN
cord-322516-wekvet6f	97	10	bands	band	NNS
cord-322516-wekvet6f	97	11	that	that	WDT
cord-322516-wekvet6f	97	12	were	be	VBD
cord-322516-wekvet6f	97	13	scraped	scrape	VBN
cord-322516-wekvet6f	97	14	and	and	CC
cord-322516-wekvet6f	97	15	counted	count	VBN
cord-322516-wekvet6f	97	16	after	after	IN
cord-322516-wekvet6f	97	17	the	the	DT
cord-322516-wekvet6f	97	18	addition	addition	NN
cord-322516-wekvet6f	97	19	of	of	IN
cord-322516-wekvet6f	97	20	scintillation	scintillation	NN
cord-322516-wekvet6f	97	21	fluid	fluid	NN
cord-322516-wekvet6f	97	22	.	.	.
cord-322516-wekvet6f	98	1	Alternatively	alternatively	RB
cord-322516-wekvet6f	98	2	,	,	,
cord-322516-wekvet6f	98	3	plates	plate	NNS
cord-322516-wekvet6f	98	4	were	be	VBD
cord-322516-wekvet6f	98	5	dipped	dip	VBN
cord-322516-wekvet6f	98	6	in	in	IN
cord-322516-wekvet6f	98	7	10	10	CD
cord-322516-wekvet6f	98	8	%	%	NN
cord-322516-wekvet6f	98	9	4,5-diphenyloxazole	4,5-diphenyloxazole	CD
cord-322516-wekvet6f	98	10	in	in	IN
cord-322516-wekvet6f	98	11	chloroform	chloroform	NN
cord-322516-wekvet6f	98	12	for	for	IN
cord-322516-wekvet6f	98	13	visualization	visualization	NN
cord-322516-wekvet6f	98	14	by	by	IN
cord-322516-wekvet6f	98	15	fluorography	fluorography	NNP
cord-322516-wekvet6f	98	16	(	(	-LRB-
cord-322516-wekvet6f	98	17	Henderson	Henderson	NNP
cord-322516-wekvet6f	98	18	and	and	CC
cord-322516-wekvet6f	98	19	Tocher	Tocher	NNP
cord-322516-wekvet6f	98	20	,	,	,
cord-322516-wekvet6f	98	21	1992	1992	CD
cord-322516-wekvet6f	98	22	)	)	-RRB-
cord-322516-wekvet6f	98	23	.	.	.
cord-322516-wekvet6f	99	1	To	to	TO
cord-322516-wekvet6f	99	2	test	test	VB
cord-322516-wekvet6f	99	3	whether	whether	IN
cord-322516-wekvet6f	99	4	ongoing	ongoing	JJ
cord-322516-wekvet6f	99	5	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	99	6	synthesis	synthesis	NN
cord-322516-wekvet6f	99	7	was	be	VBD
cord-322516-wekvet6f	99	8	necessary	necessary	JJ
cord-322516-wekvet6f	99	9	for	for	IN
cord-322516-wekvet6f	99	10	the	the	DT
cord-322516-wekvet6f	99	11	correct	correct	JJ
cord-322516-wekvet6f	99	12	localization	localization	NN
cord-322516-wekvet6f	99	13	of	of	IN
cord-322516-wekvet6f	99	14	the	the	DT
cord-322516-wekvet6f	99	15	IBV	IBV	NNP
cord-322516-wekvet6f	99	16	M	M	NNP
cord-322516-wekvet6f	99	17	protein	protein	NN
cord-322516-wekvet6f	99	18	,	,	,
cord-322516-wekvet6f	99	19	we	-PRON-	PRP
cord-322516-wekvet6f	99	20	used	use	VBD
cord-322516-wekvet6f	99	21	three	three	CD
cord-322516-wekvet6f	99	22	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	99	23	of	of	IN
cord-322516-wekvet6f	99	24	sphingolipid	sphingolipid	NNP
cord-322516-wekvet6f	99	25	synthesis	synthesis	NN
cord-322516-wekvet6f	99	26	:	:	:
cord-322516-wekvet6f	99	27	␤	␤	.
cord-322516-wekvet6f	100	1	-chloroalanine	-chloroalanine	.
cord-322516-wekvet6f	101	1	(	(	-LRB-
cord-322516-wekvet6f	101	2	␤	␤	.
cord-322516-wekvet6f	102	1	CA	CA	NNP
cord-322516-wekvet6f	102	2	;	;	:
cord-322516-wekvet6f	102	3	Medlock	Medlock	NNP
cord-322516-wekvet6f	102	4	and	and	CC
cord-322516-wekvet6f	102	5	Merrill	Merrill	NNP
cord-322516-wekvet6f	102	6	,	,	,
cord-322516-wekvet6f	102	7	1988	1988	CD
cord-322516-wekvet6f	102	8	)	)	-RRB-
cord-322516-wekvet6f	102	9	,	,	,
cord-322516-wekvet6f	102	10	fumonisin	fumonisin	NNP
cord-322516-wekvet6f	102	11	B1	B1	NNP
cord-322516-wekvet6f	102	12	(	(	-LRB-
cord-322516-wekvet6f	102	13	FB1	FB1	NNP
cord-322516-wekvet6f	102	14	;	;	:
cord-322516-wekvet6f	102	15	Wang	Wang	NNP
cord-322516-wekvet6f	102	16	et	et	NNP
cord-322516-wekvet6f	102	17	al	al	NNP
cord-322516-wekvet6f	102	18	.	.	NNP
cord-322516-wekvet6f	102	19	,	,	,
cord-322516-wekvet6f	102	20	1991	1991	CD
cord-322516-wekvet6f	102	21	)	)	-RRB-
cord-322516-wekvet6f	102	22	,	,	,
cord-322516-wekvet6f	102	23	and	and	CC
cord-322516-wekvet6f	102	24	PDMP	PDMP	NNP
cord-322516-wekvet6f	102	25	(	(	-LRB-
cord-322516-wekvet6f	102	26	Vunnam	Vunnam	NNP
cord-322516-wekvet6f	102	27	and	and	CC
cord-322516-wekvet6f	102	28	Radin	Radin	NNP
cord-322516-wekvet6f	102	29	,	,	,
cord-322516-wekvet6f	102	30	1980	1980	CD
cord-322516-wekvet6f	102	31	;	;	:
cord-322516-wekvet6f	102	32	Inokuchi	Inokuchi	NNP
cord-322516-wekvet6f	102	33	and	and	CC
cord-322516-wekvet6f	102	34	Radin	Radin	NNP
cord-322516-wekvet6f	102	35	,	,	,
cord-322516-wekvet6f	102	36	1987	1987	CD
cord-322516-wekvet6f	102	37	)	)	-RRB-
cord-322516-wekvet6f	102	38	.	.	.
cord-322516-wekvet6f	103	1	The	the	DT
cord-322516-wekvet6f	103	2	biosynthetic	biosynthetic	JJ
cord-322516-wekvet6f	103	3	pathway	pathway	NN
cord-322516-wekvet6f	103	4	for	for	IN
cord-322516-wekvet6f	103	5	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	103	6	with	with	IN
cord-322516-wekvet6f	103	7	the	the	DT
cord-322516-wekvet6f	103	8	sites	site	NNS
cord-322516-wekvet6f	103	9	of	of	IN
cord-322516-wekvet6f	103	10	inhibition	inhibition	NN
cord-322516-wekvet6f	103	11	of	of	IN
cord-322516-wekvet6f	103	12	these	these	DT
cord-322516-wekvet6f	103	13	drugs	drug	NNS
cord-322516-wekvet6f	103	14	is	be	VBZ
cord-322516-wekvet6f	103	15	shown	show	VBN
cord-322516-wekvet6f	103	16	in	in	IN
cord-322516-wekvet6f	103	17	Fig	Fig	NNP
cord-322516-wekvet6f	103	18	.	.	.
cord-322516-wekvet6f	104	1	1	1	LS
cord-322516-wekvet6f	104	2	.	.	.
cord-322516-wekvet6f	105	1	Both	both	DT
cord-322516-wekvet6f	105	2	␤	␤	``
cord-322516-wekvet6f	105	3	CA	CA	NNP
cord-322516-wekvet6f	105	4	(	(	-LRB-
cord-322516-wekvet6f	105	5	5	5	CD
cord-322516-wekvet6f	105	6	mM	mm	CD
cord-322516-wekvet6f	105	7	)	)	-RRB-
cord-322516-wekvet6f	105	8	and	and	CC
cord-322516-wekvet6f	105	9	FB1	FB1	NNP
cord-322516-wekvet6f	105	10	(	(	-LRB-
cord-322516-wekvet6f	105	11	100	100	CD
cord-322516-wekvet6f	105	12	M	M	NNP
cord-322516-wekvet6f	105	13	)	)	-RRB-
cord-322516-wekvet6f	105	14	inhibited	inhibit	VBD
cord-322516-wekvet6f	105	15	the	the	DT
cord-322516-wekvet6f	105	16	incorporation	incorporation	NN
cord-322516-wekvet6f	105	17	of	of	IN
cord-322516-wekvet6f	105	18	radiolabeled	radiolabele	VBN
cord-322516-wekvet6f	105	19	precursors	precursor	NNS
cord-322516-wekvet6f	105	20	into	into	IN
cord-322516-wekvet6f	105	21	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	105	22	in	in	IN
cord-322516-wekvet6f	105	23	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	105	24	cells	cell	NNS
cord-322516-wekvet6f	105	25	by	by	IN
cord-322516-wekvet6f	105	26	Ͼ	ͼ	NN
cord-322516-wekvet6f	105	27	90	90	CD
cord-322516-wekvet6f	105	28	%	%	NN
cord-322516-wekvet6f	105	29	(	(	-LRB-
cord-322516-wekvet6f	105	30	data	datum	NNS
cord-322516-wekvet6f	105	31	not	not	RB
cord-322516-wekvet6f	105	32	shown	show	VBN
cord-322516-wekvet6f	105	33	)	)	-RRB-
cord-322516-wekvet6f	105	34	.	.	.
cord-322516-wekvet6f	106	1	Consistent	consistent	JJ
cord-322516-wekvet6f	106	2	with	with	IN
cord-322516-wekvet6f	106	3	previous	previous	JJ
cord-322516-wekvet6f	106	4	results	result	NNS
cord-322516-wekvet6f	106	5	(	(	-LRB-
cord-322516-wekvet6f	106	6	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	106	7	et	et	NNP
cord-322516-wekvet6f	106	8	al	al	NNP
cord-322516-wekvet6f	106	9	.	.	NNP
cord-322516-wekvet6f	106	10	,	,	,
cord-322516-wekvet6f	106	11	1992	1992	CD
cord-322516-wekvet6f	106	12	)	)	-RRB-
cord-322516-wekvet6f	106	13	,	,	,
cord-322516-wekvet6f	106	14	we	-PRON-	PRP
cord-322516-wekvet6f	106	15	found	find	VBD
cord-322516-wekvet6f	106	16	that	that	IN
cord-322516-wekvet6f	106	17	PDMP	PDMP	NNP
cord-322516-wekvet6f	106	18	(	(	-LRB-
cord-322516-wekvet6f	106	19	100	100	CD
cord-322516-wekvet6f	106	20	M	M	NNP
cord-322516-wekvet6f	106	21	)	)	-RRB-
cord-322516-wekvet6f	106	22	inhibited	inhibit	VBD
cord-322516-wekvet6f	106	23	GlcCer	GlcCer	NNP
cord-322516-wekvet6f	106	24	synthesis	synthesis	NN
cord-322516-wekvet6f	106	25	by	by	IN
cord-322516-wekvet6f	106	26	‫ف‬	‫ف‬	NNP
cord-322516-wekvet6f	106	27	90	90	CD
cord-322516-wekvet6f	106	28	%	%	NN
cord-322516-wekvet6f	106	29	and	and	CC
cord-322516-wekvet6f	106	30	SM	sm	NN
cord-322516-wekvet6f	106	31	synthesis	synthesis	NN
cord-322516-wekvet6f	106	32	by	by	IN
cord-322516-wekvet6f	106	33	‫ف‬	‫ف‬	NNP
cord-322516-wekvet6f	106	34	50	50	CD
cord-322516-wekvet6f	106	35	%	%	NN
cord-322516-wekvet6f	106	36	in	in	IN
cord-322516-wekvet6f	106	37	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	106	38	cells	cell	NNS
cord-322516-wekvet6f	106	39	(	(	-LRB-
cord-322516-wekvet6f	106	40	data	datum	NNS
cord-322516-wekvet6f	106	41	not	not	RB
cord-322516-wekvet6f	106	42	shown	show	VBN
cord-322516-wekvet6f	106	43	)	)	-RRB-
cord-322516-wekvet6f	106	44	.	.	.
cord-322516-wekvet6f	107	1	To	to	TO
cord-322516-wekvet6f	107	2	express	express	VB
cord-322516-wekvet6f	107	3	the	the	DT
cord-322516-wekvet6f	107	4	IBV	IBV	NNP
cord-322516-wekvet6f	107	5	M	M	NNP
cord-322516-wekvet6f	107	6	protein	protein	NN
cord-322516-wekvet6f	107	7	,	,	,
cord-322516-wekvet6f	107	8	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	107	9	cells	cell	NNS
cord-322516-wekvet6f	107	10	were	be	VBD
cord-322516-wekvet6f	107	11	infected	infect	VBN
cord-322516-wekvet6f	107	12	with	with	IN
cord-322516-wekvet6f	107	13	a	a	DT
cord-322516-wekvet6f	107	14	recombinant	recombinant	JJ
cord-322516-wekvet6f	107	15	vaccinia	vaccinia	NN
cord-322516-wekvet6f	107	16	virus	virus	NN
cord-322516-wekvet6f	107	17	encoding	encode	VBG
cord-322516-wekvet6f	107	18	IBV	IBV	NNP
cord-322516-wekvet6f	107	19	M	M	NNP
cord-322516-wekvet6f	107	20	(	(	-LRB-
cord-322516-wekvet6f	107	21	Machamer	Machamer	NNP
cord-322516-wekvet6f	107	22	and	and	CC
cord-322516-wekvet6f	107	23	Rose	Rose	NNP
cord-322516-wekvet6f	107	24	,	,	,
cord-322516-wekvet6f	107	25	1987	1987	CD
cord-322516-wekvet6f	107	26	)	)	-RRB-
cord-322516-wekvet6f	107	27	.	.	.
cord-322516-wekvet6f	108	1	4	4	LS
cord-322516-wekvet6f	108	2	h	h	NN
cord-322516-wekvet6f	108	3	after	after	IN
cord-322516-wekvet6f	108	4	infection	infection	NN
cord-322516-wekvet6f	108	5	the	the	DT
cord-322516-wekvet6f	108	6	cells	cell	NNS
cord-322516-wekvet6f	108	7	were	be	VBD
cord-322516-wekvet6f	108	8	treated	treat	VBN
cord-322516-wekvet6f	108	9	with	with	IN
cord-322516-wekvet6f	108	10	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	108	11	for	for	IN
cord-322516-wekvet6f	108	12	1	1	CD
cord-322516-wekvet6f	108	13	h	h	NN
cord-322516-wekvet6f	108	14	to	to	TO
cord-322516-wekvet6f	108	15	chase	chase	VB
cord-322516-wekvet6f	108	16	newly	newly	RB
cord-322516-wekvet6f	108	17	synthesized	synthesize	VBN
cord-322516-wekvet6f	108	18	M	M	NNP
cord-322516-wekvet6f	108	19	protein	protein	NN
cord-322516-wekvet6f	108	20	out	out	IN
cord-322516-wekvet6f	108	21	of	of	IN
cord-322516-wekvet6f	108	22	the	the	DT
cord-322516-wekvet6f	108	23	ER	ER	NNP
cord-322516-wekvet6f	108	24	.	.	.
cord-322516-wekvet6f	109	1	Sphingolipid	Sphingolipid	NNP
cord-322516-wekvet6f	109	2	synthesis	synthesis	NN
cord-322516-wekvet6f	109	3	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	109	4	were	be	VBD
cord-322516-wekvet6f	109	5	then	then	RB
cord-322516-wekvet6f	109	6	added	add	VBN
cord-322516-wekvet6f	109	7	and	and	CC
cord-322516-wekvet6f	109	8	the	the	DT
cord-322516-wekvet6f	109	9	cells	cell	NNS
cord-322516-wekvet6f	109	10	incubated	incubate	VBN
cord-322516-wekvet6f	109	11	for	for	IN
cord-322516-wekvet6f	109	12	another	another	DT
cord-322516-wekvet6f	109	13	1	1	CD
cord-322516-wekvet6f	109	14	h	h	NN
cord-322516-wekvet6f	109	15	before	before	IN
cord-322516-wekvet6f	109	16	processing	process	VBG
cord-322516-wekvet6f	109	17	for	for	IN
cord-322516-wekvet6f	109	18	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	109	19	(	(	-LRB-
cord-322516-wekvet6f	109	20	Fig	Fig	NNP
cord-322516-wekvet6f	109	21	.	.	NNP
cord-322516-wekvet6f	109	22	2	2	CD
cord-322516-wekvet6f	109	23	)	)	-RRB-
cord-322516-wekvet6f	109	24	.	.	.
cord-322516-wekvet6f	110	1	In	in	IN
cord-322516-wekvet6f	110	2	control	control	NN
cord-322516-wekvet6f	110	3	cells	cell	NNS
cord-322516-wekvet6f	110	4	,	,	,
cord-322516-wekvet6f	110	5	IBV	IBV	NNP
cord-322516-wekvet6f	110	6	M	M	NNP
cord-322516-wekvet6f	110	7	exhibited	exhibit	VBD
cord-322516-wekvet6f	110	8	a	a	DT
cord-322516-wekvet6f	110	9	tight	tight	JJ
cord-322516-wekvet6f	110	10	,	,	,
cord-322516-wekvet6f	110	11	juxtanuclear	juxtanuclear	NN
cord-322516-wekvet6f	110	12	staining	staining	NN
cord-322516-wekvet6f	110	13	pattern	pattern	NN
cord-322516-wekvet6f	110	14	that	that	WDT
cord-322516-wekvet6f	110	15	colocalized	colocalize	VBN
cord-322516-wekvet6f	110	16	with	with	IN
cord-322516-wekvet6f	110	17	Golgi	Golgi	NNP
cord-322516-wekvet6f	110	18	markers	marker	NNS
cord-322516-wekvet6f	110	19	.	.	.
cord-322516-wekvet6f	111	1	The	the	DT
cord-322516-wekvet6f	111	2	Golgi	Golgi	NNP
cord-322516-wekvet6f	111	3	localization	localization	NN
cord-322516-wekvet6f	111	4	pattern	pattern	NN
cord-322516-wekvet6f	111	5	of	of	IN
cord-322516-wekvet6f	111	6	IBV	IBV	NNP
cord-322516-wekvet6f	111	7	M	M	NNP
cord-322516-wekvet6f	111	8	was	be	VBD
cord-322516-wekvet6f	111	9	unchanged	unchanged	JJ
cord-322516-wekvet6f	111	10	by	by	IN
cord-322516-wekvet6f	111	11	treatment	treatment	NN
cord-322516-wekvet6f	111	12	with	with	IN
cord-322516-wekvet6f	111	13	either	either	CC
cord-322516-wekvet6f	111	14	␤	␤	NNP
cord-322516-wekvet6f	111	15	CA	CA	NNP
cord-322516-wekvet6f	111	16	or	or	CC
cord-322516-wekvet6f	111	17	FB1	FB1	NNP
cord-322516-wekvet6f	111	18	,	,	,
cord-322516-wekvet6f	111	19	suggesting	suggest	VBG
cord-322516-wekvet6f	111	20	that	that	IN
cord-322516-wekvet6f	111	21	ongoing	ongoing	JJ
cord-322516-wekvet6f	111	22	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	111	23	synthesis	synthesis	NN
cord-322516-wekvet6f	111	24	is	be	VBZ
cord-322516-wekvet6f	111	25	not	not	RB
cord-322516-wekvet6f	111	26	required	require	VBN
cord-322516-wekvet6f	111	27	for	for	IN
cord-322516-wekvet6f	111	28	proper	proper	JJ
cord-322516-wekvet6f	111	29	localization	localization	NN
cord-322516-wekvet6f	111	30	of	of	IN
cord-322516-wekvet6f	111	31	IBV	IBV	NNP
cord-322516-wekvet6f	111	32	M.	M.	NNP
cord-322516-wekvet6f	112	1	In	in	IN
cord-322516-wekvet6f	112	2	contrast	contrast	NN
cord-322516-wekvet6f	112	3	,	,	,
cord-322516-wekvet6f	112	4	PDMP	PDMP	NNP
cord-322516-wekvet6f	112	5	-	-	HYPH
cord-322516-wekvet6f	112	6	treated	treat	VBN
cord-322516-wekvet6f	112	7	cells	cell	NNS
cord-322516-wekvet6f	112	8	showed	show	VBD
cord-322516-wekvet6f	112	9	a	a	DT
cord-322516-wekvet6f	112	10	marked	marked	JJ
cord-322516-wekvet6f	112	11	change	change	NN
cord-322516-wekvet6f	112	12	in	in	IN
cord-322516-wekvet6f	112	13	the	the	DT
cord-322516-wekvet6f	112	14	staining	staining	NN
cord-322516-wekvet6f	112	15	pattern	pattern	NN
cord-322516-wekvet6f	112	16	of	of	IN
cord-322516-wekvet6f	112	17	the	the	DT
cord-322516-wekvet6f	112	18	IBV	IBV	NNP
cord-322516-wekvet6f	112	19	M	M	NNP
cord-322516-wekvet6f	112	20	pro	pro	NNP
cord-322516-wekvet6f	112	21	-	-	JJ
cord-322516-wekvet6f	112	22	tein	tein	NNP
cord-322516-wekvet6f	112	23	after	after	IN
cord-322516-wekvet6f	112	24	1	1	CD
cord-322516-wekvet6f	112	25	h.	h.	NN
cord-322516-wekvet6f	113	1	The	the	DT
cord-322516-wekvet6f	113	2	localization	localization	NN
cord-322516-wekvet6f	113	3	of	of	IN
cord-322516-wekvet6f	113	4	IBV	IBV	NNP
cord-322516-wekvet6f	113	5	M	M	NNP
cord-322516-wekvet6f	113	6	in	in	IN
cord-322516-wekvet6f	113	7	the	the	DT
cord-322516-wekvet6f	113	8	presence	presence	NN
cord-322516-wekvet6f	113	9	of	of	IN
cord-322516-wekvet6f	113	10	PDMP	PDMP	NNP
cord-322516-wekvet6f	113	11	changed	change	VBD
cord-322516-wekvet6f	113	12	from	from	IN
cord-322516-wekvet6f	113	13	Golgi	Golgi	NNP
cord-322516-wekvet6f	113	14	to	to	IN
cord-322516-wekvet6f	113	15	ER	ER	NNP
cord-322516-wekvet6f	113	16	based	base	VBN
cord-322516-wekvet6f	113	17	on	on	IN
cord-322516-wekvet6f	113	18	the	the	DT
cord-322516-wekvet6f	113	19	absence	absence	NN
cord-322516-wekvet6f	113	20	of	of	IN
cord-322516-wekvet6f	113	21	strong	strong	JJ
cord-322516-wekvet6f	113	22	juxtanuclear	juxtanuclear	NN
cord-322516-wekvet6f	113	23	staining	staining	NN
cord-322516-wekvet6f	113	24	and	and	CC
cord-322516-wekvet6f	113	25	the	the	DT
cord-322516-wekvet6f	113	26	presence	presence	NN
cord-322516-wekvet6f	113	27	of	of	IN
cord-322516-wekvet6f	113	28	nuclear	nuclear	JJ
cord-322516-wekvet6f	113	29	rim	rim	NN
cord-322516-wekvet6f	113	30	staining	staining	NN
cord-322516-wekvet6f	113	31	and	and	CC
cord-322516-wekvet6f	113	32	a	a	DT
cord-322516-wekvet6f	113	33	tubulo	tubulo	JJ
cord-322516-wekvet6f	113	34	-	-	HYPH
cord-322516-wekvet6f	113	35	reticular	reticular	JJ
cord-322516-wekvet6f	113	36	staining	staining	NN
cord-322516-wekvet6f	113	37	pattern	pattern	NN
cord-322516-wekvet6f	113	38	that	that	WDT
cord-322516-wekvet6f	113	39	colocalized	colocalize	VBN
cord-322516-wekvet6f	113	40	with	with	IN
cord-322516-wekvet6f	113	41	ER	ER	NNP
cord-322516-wekvet6f	113	42	markers	marker	NNS
cord-322516-wekvet6f	113	43	.	.	.
cord-322516-wekvet6f	114	1	Treatment	treatment	NN
cord-322516-wekvet6f	114	2	of	of	IN
cord-322516-wekvet6f	114	3	infected	infected	JJ
cord-322516-wekvet6f	114	4	cells	cell	NNS
cord-322516-wekvet6f	114	5	with	with	IN
cord-322516-wekvet6f	114	6	lower	low	JJR
cord-322516-wekvet6f	114	7	concentrations	concentration	NNS
cord-322516-wekvet6f	114	8	of	of	IN
cord-322516-wekvet6f	114	9	PDMP	PDMP	NNP
cord-322516-wekvet6f	114	10	had	have	VBD
cord-322516-wekvet6f	114	11	no	no	DT
cord-322516-wekvet6f	114	12	effect	effect	NN
cord-322516-wekvet6f	114	13	on	on	IN
cord-322516-wekvet6f	114	14	IBV	IBV	NNP
cord-322516-wekvet6f	114	15	M	M	NNP
cord-322516-wekvet6f	114	16	localization	localization	NN
cord-322516-wekvet6f	114	17	and	and	CC
cord-322516-wekvet6f	114	18	very	very	RB
cord-322516-wekvet6f	114	19	little	little	JJ
cord-322516-wekvet6f	114	20	effect	effect	NN
cord-322516-wekvet6f	114	21	on	on	IN
cord-322516-wekvet6f	114	22	SM	sm	NN
cord-322516-wekvet6f	114	23	synthesis	synthesis	NN
cord-322516-wekvet6f	114	24	(	(	-LRB-
cord-322516-wekvet6f	114	25	data	datum	NNS
cord-322516-wekvet6f	114	26	not	not	RB
cord-322516-wekvet6f	114	27	shown	show	VBN
cord-322516-wekvet6f	114	28	)	)	-RRB-
cord-322516-wekvet6f	114	29	.	.	.
cord-322516-wekvet6f	115	1	We	-PRON-	PRP
cord-322516-wekvet6f	115	2	next	next	RB
cord-322516-wekvet6f	115	3	tested	test	VBD
cord-322516-wekvet6f	115	4	the	the	DT
cord-322516-wekvet6f	115	5	kinetics	kinetic	NNS
cord-322516-wekvet6f	115	6	of	of	IN
cord-322516-wekvet6f	115	7	PDMP	PDMP	NNP
cord-322516-wekvet6f	115	8	-	-	HYPH
cord-322516-wekvet6f	115	9	induced	induce	VBN
cord-322516-wekvet6f	115	10	mislocalization	mislocalization	NN
cord-322516-wekvet6f	115	11	of	of	IN
cord-322516-wekvet6f	115	12	IBV	IBV	NNP
cord-322516-wekvet6f	115	13	M.	M.	NNP
cord-322516-wekvet6f	115	14	Cells	Cells	NNP
cord-322516-wekvet6f	115	15	were	be	VBD
cord-322516-wekvet6f	115	16	infected	infect	VBN
cord-322516-wekvet6f	115	17	as	as	IN
cord-322516-wekvet6f	115	18	before	before	RB
cord-322516-wekvet6f	115	19	and	and	CC
cord-322516-wekvet6f	115	20	treated	treat	VBN
cord-322516-wekvet6f	115	21	for	for	IN
cord-322516-wekvet6f	115	22	1	1	CD
cord-322516-wekvet6f	115	23	h	h	NN
cord-322516-wekvet6f	115	24	with	with	IN
cord-322516-wekvet6f	115	25	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	115	26	.	.	.
cord-322516-wekvet6f	116	1	Then	then	RB
cord-322516-wekvet6f	116	2	cells	cell	NNS
cord-322516-wekvet6f	116	3	were	be	VBD
cord-322516-wekvet6f	116	4	treated	treat	VBN
cord-322516-wekvet6f	116	5	with	with	IN
cord-322516-wekvet6f	116	6	PDMP	PDMP	NNP
cord-322516-wekvet6f	116	7	for	for	IN
cord-322516-wekvet6f	116	8	varying	vary	VBG
cord-322516-wekvet6f	116	9	lengths	length	NNS
cord-322516-wekvet6f	116	10	of	of	IN
cord-322516-wekvet6f	116	11	time	time	NN
cord-322516-wekvet6f	116	12	up	up	IN
cord-322516-wekvet6f	116	13	to	to	IN
cord-322516-wekvet6f	116	14	1	1	CD
cord-322516-wekvet6f	116	15	h	h	NN
cord-322516-wekvet6f	116	16	(	(	-LRB-
cord-322516-wekvet6f	116	17	Fig	Fig	NNP
cord-322516-wekvet6f	116	18	.	.	.
cord-322516-wekvet6f	116	19	3	3	CD
cord-322516-wekvet6f	116	20	)	)	-RRB-
cord-322516-wekvet6f	116	21	.	.	.
cord-322516-wekvet6f	117	1	Redistribution	redistribution	NN
cord-322516-wekvet6f	117	2	was	be	VBD
cord-322516-wekvet6f	117	3	first	first	RB
cord-322516-wekvet6f	117	4	observed	observe	VBN
cord-322516-wekvet6f	117	5	at	at	IN
cord-322516-wekvet6f	117	6	15	15	CD
cord-322516-wekvet6f	117	7	min	min	NN
cord-322516-wekvet6f	117	8	and	and	CC
cord-322516-wekvet6f	117	9	became	become	VBD
cord-322516-wekvet6f	117	10	maximal	maximal	JJ
cord-322516-wekvet6f	117	11	at	at	IN
cord-322516-wekvet6f	117	12	60	60	CD
cord-322516-wekvet6f	117	13	min	min	NN
cord-322516-wekvet6f	117	14	.	.	.
cord-322516-wekvet6f	118	1	This	this	DT
cord-322516-wekvet6f	118	2	redistribution	redistribution	NN
cord-322516-wekvet6f	118	3	was	be	VBD
cord-322516-wekvet6f	118	4	rapidly	rapidly	RB
cord-322516-wekvet6f	118	5	reversible	reversible	JJ
cord-322516-wekvet6f	118	6	,	,	,
cord-322516-wekvet6f	118	7	such	such	JJ
cord-322516-wekvet6f	118	8	that	that	IN
cord-322516-wekvet6f	118	9	30	30	CD
cord-322516-wekvet6f	118	10	min	min	NN
cord-322516-wekvet6f	118	11	after	after	IN
cord-322516-wekvet6f	118	12	washing	wash	VBG
cord-322516-wekvet6f	118	13	out	out	RP
cord-322516-wekvet6f	118	14	PDMP	PDMP	NNP
cord-322516-wekvet6f	118	15	,	,	,
cord-322516-wekvet6f	118	16	IBV	IBV	NNP
cord-322516-wekvet6f	118	17	M	M	NNP
cord-322516-wekvet6f	118	18	had	have	VBD
cord-322516-wekvet6f	118	19	moved	move	VBN
cord-322516-wekvet6f	118	20	back	back	RB
cord-322516-wekvet6f	118	21	to	to	IN
cord-322516-wekvet6f	118	22	the	the	DT
cord-322516-wekvet6f	118	23	Golgi	Golgi	NNP
cord-322516-wekvet6f	118	24	region	region	NN
cord-322516-wekvet6f	118	25	.	.	.
cord-322516-wekvet6f	119	1	We	-PRON-	PRP
cord-322516-wekvet6f	119	2	next	next	RB
cord-322516-wekvet6f	119	3	asked	ask	VBD
cord-322516-wekvet6f	119	4	if	if	IN
cord-322516-wekvet6f	119	5	PDMP	PDMP	NNP
cord-322516-wekvet6f	119	6	mislocalized	mislocalize	VBD
cord-322516-wekvet6f	119	7	other	other	JJ
cord-322516-wekvet6f	119	8	Golgi	Golgi	NNP
cord-322516-wekvet6f	119	9	markers	marker	NNS
cord-322516-wekvet6f	119	10	.	.	.
cord-322516-wekvet6f	120	1	Cells	cell	NNS
cord-322516-wekvet6f	120	2	were	be	VBD
cord-322516-wekvet6f	120	3	infected	infect	VBN
cord-322516-wekvet6f	120	4	and	and	CC
cord-322516-wekvet6f	120	5	treated	treat	VBN
cord-322516-wekvet6f	120	6	as	as	IN
cord-322516-wekvet6f	120	7	described	describe	VBN
cord-322516-wekvet6f	120	8	above	above	RB
cord-322516-wekvet6f	120	9	and	and	CC
cord-322516-wekvet6f	120	10	then	then	RB
cord-322516-wekvet6f	120	11	stained	stain	VBN
cord-322516-wekvet6f	120	12	with	with	IN
cord-322516-wekvet6f	120	13	antibodies	antibody	NNS
cord-322516-wekvet6f	120	14	to	to	IN
cord-322516-wekvet6f	120	15	two	two	CD
cord-322516-wekvet6f	120	16	integral	integral	JJ
cord-322516-wekvet6f	120	17	membrane	membrane	NN
cord-322516-wekvet6f	120	18	proteins	protein	NNS
cord-322516-wekvet6f	120	19	of	of	IN
cord-322516-wekvet6f	120	20	the	the	DT
cord-322516-wekvet6f	120	21	Golgi	Golgi	NNP
cord-322516-wekvet6f	120	22	stack	stack	NN
cord-322516-wekvet6f	120	23	,	,	,
cord-322516-wekvet6f	120	24	giantin	giantin	NNP
cord-322516-wekvet6f	120	25	(	(	-LRB-
cord-322516-wekvet6f	120	26	Linstedt	Linstedt	NNP
cord-322516-wekvet6f	120	27	and	and	CC
cord-322516-wekvet6f	120	28	Hauri	Hauri	NNP
cord-322516-wekvet6f	120	29	,	,	,
cord-322516-wekvet6f	120	30	1993	1993	CD
cord-322516-wekvet6f	120	31	)	)	-RRB-
cord-322516-wekvet6f	120	32	and	and	CC
cord-322516-wekvet6f	120	33	mannosidase	mannosidase	NNP
cord-322516-wekvet6f	120	34	II	II	NNP
cord-322516-wekvet6f	120	35	(	(	-LRB-
cord-322516-wekvet6f	120	36	Man	Man	NNP
cord-322516-wekvet6f	120	37	II	II	NNP
cord-322516-wekvet6f	120	38	;	;	:
cord-322516-wekvet6f	120	39	Moremen	Moremen	NNP
cord-322516-wekvet6f	120	40	and	and	CC
cord-322516-wekvet6f	120	41	Robbins	Robbins	NNP
cord-322516-wekvet6f	120	42	,	,	,
cord-322516-wekvet6f	120	43	1991	1991	CD
cord-322516-wekvet6f	120	44	;	;	:
cord-322516-wekvet6f	121	1	Velasco	Velasco	NNP
cord-322516-wekvet6f	121	2	et	et	NNP
cord-322516-wekvet6f	121	3	al	al	NNP
cord-322516-wekvet6f	121	4	.	.	NNP
cord-322516-wekvet6f	121	5	,	,	,
cord-322516-wekvet6f	121	6	1993	1993	CD
cord-322516-wekvet6f	121	7	)	)	-RRB-
cord-322516-wekvet6f	121	8	.	.	.
cord-322516-wekvet6f	122	1	Treatment	treatment	NN
cord-322516-wekvet6f	122	2	of	of	IN
cord-322516-wekvet6f	122	3	cells	cell	NNS
cord-322516-wekvet6f	122	4	with	with	IN
cord-322516-wekvet6f	122	5	100	100	CD
cord-322516-wekvet6f	122	6	M	M	NNP
cord-322516-wekvet6f	122	7	PDMP	PDMP	NNP
cord-322516-wekvet6f	122	8	for	for	IN
cord-322516-wekvet6f	122	9	1	1	CD
cord-322516-wekvet6f	122	10	h	h	NN
cord-322516-wekvet6f	122	11	had	have	VBD
cord-322516-wekvet6f	122	12	no	no	DT
cord-322516-wekvet6f	122	13	effect	effect	NN
cord-322516-wekvet6f	122	14	on	on	IN
cord-322516-wekvet6f	122	15	the	the	DT
cord-322516-wekvet6f	122	16	localization	localization	NN
cord-322516-wekvet6f	122	17	of	of	IN
cord-322516-wekvet6f	122	18	either	either	DT
cord-322516-wekvet6f	122	19	protein	protein	NN
cord-322516-wekvet6f	122	20	(	(	-LRB-
cord-322516-wekvet6f	122	21	Fig	Fig	NNP
cord-322516-wekvet6f	122	22	.	.	.
cord-322516-wekvet6f	122	23	4	4	CD
cord-322516-wekvet6f	122	24	)	)	-RRB-
cord-322516-wekvet6f	122	25	,	,	,
cord-322516-wekvet6f	122	26	suggesting	suggest	VBG
cord-322516-wekvet6f	122	27	that	that	IN
cord-322516-wekvet6f	122	28	the	the	DT
cord-322516-wekvet6f	122	29	morphology	morphology	NN
cord-322516-wekvet6f	122	30	of	of	IN
cord-322516-wekvet6f	122	31	the	the	DT
cord-322516-wekvet6f	122	32	Golgi	Golgi	NNP
cord-322516-wekvet6f	122	33	was	be	VBD
cord-322516-wekvet6f	122	34	not	not	RB
cord-322516-wekvet6f	122	35	greatly	greatly	RB
cord-322516-wekvet6f	122	36	altered	alter	VBN
cord-322516-wekvet6f	122	37	.	.	.
cord-322516-wekvet6f	123	1	We	-PRON-	PRP
cord-322516-wekvet6f	123	2	also	also	RB
cord-322516-wekvet6f	123	3	examined	examine	VBD
cord-322516-wekvet6f	123	4	the	the	DT
cord-322516-wekvet6f	123	5	localization	localization	NN
cord-322516-wekvet6f	123	6	of	of	IN
cord-322516-wekvet6f	123	7	␤	␤	NNP
cord-322516-wekvet6f	123	8	-COP	-COP	JJR
cord-322516-wekvet6f	123	9	,	,	,
cord-322516-wekvet6f	123	10	a	a	DT
cord-322516-wekvet6f	123	11	peripheral	peripheral	JJ
cord-322516-wekvet6f	123	12	membrane	membrane	NN
cord-322516-wekvet6f	123	13	protein	protein	NN
cord-322516-wekvet6f	123	14	of	of	IN
cord-322516-wekvet6f	123	15	the	the	DT
cord-322516-wekvet6f	123	16	stack	stack	NN
cord-322516-wekvet6f	123	17	and	and	CC
cord-322516-wekvet6f	123	18	CGN	CGN	NNP
cord-322516-wekvet6f	123	19	involved	involve	VBN
cord-322516-wekvet6f	123	20	in	in	IN
cord-322516-wekvet6f	123	21	vesicular	vesicular	JJ
cord-322516-wekvet6f	123	22	traffic	traffic	NN
cord-322516-wekvet6f	124	1	(	(	-LRB-
cord-322516-wekvet6f	124	2	Oprins	Oprins	NNP
cord-322516-wekvet6f	124	3	et	et	NNP
cord-322516-wekvet6f	124	4	al	al	NNP
cord-322516-wekvet6f	124	5	.	.	NNP
cord-322516-wekvet6f	124	6	,	,	,
cord-322516-wekvet6f	124	7	1993	1993	CD
cord-322516-wekvet6f	124	8	)	)	-RRB-
cord-322516-wekvet6f	124	9	.	.	.
cord-322516-wekvet6f	125	1	As	as	IN
cord-322516-wekvet6f	125	2	seen	see	VBN
cord-322516-wekvet6f	125	3	in	in	IN
cord-322516-wekvet6f	125	4	Fig	Fig	NNP
cord-322516-wekvet6f	125	5	.	.	NNP
cord-322516-wekvet6f	125	6	4	4	CD
cord-322516-wekvet6f	125	7	,	,	,
cord-322516-wekvet6f	125	8	the	the	DT
cord-322516-wekvet6f	125	9	distribution	distribution	NN
cord-322516-wekvet6f	125	10	of	of	IN
cord-322516-wekvet6f	125	11	␤	␤	NNP
cord-322516-wekvet6f	125	12	-COP	-cop	WP
cord-322516-wekvet6f	125	13	appeared	appear	VBD
cord-322516-wekvet6f	125	14	unaffected	unaffected	JJ
cord-322516-wekvet6f	125	15	in	in	IN
cord-322516-wekvet6f	125	16	treated	treat	VBN
cord-322516-wekvet6f	125	17	cells	cell	NNS
cord-322516-wekvet6f	125	18	.	.	.
cord-322516-wekvet6f	126	1	We	-PRON-	PRP
cord-322516-wekvet6f	126	2	then	then	RB
cord-322516-wekvet6f	126	3	looked	look	VBD
cord-322516-wekvet6f	126	4	at	at	IN
cord-322516-wekvet6f	126	5	a	a	DT
cord-322516-wekvet6f	126	6	protein	protein	NN
cord-322516-wekvet6f	126	7	which	which	WDT
cord-322516-wekvet6f	126	8	cycles	cycle	VBZ
cord-322516-wekvet6f	126	9	through	through	IN
cord-322516-wekvet6f	126	10	the	the	DT
cord-322516-wekvet6f	126	11	cis	cis	NNP
cord-322516-wekvet6f	126	12	-Golgi	-golgi	ADD
cord-322516-wekvet6f	126	13	.	.	.
cord-322516-wekvet6f	127	1	As	as	IN
cord-322516-wekvet6f	127	2	we	-PRON-	PRP
cord-322516-wekvet6f	127	3	did	do	VBD
cord-322516-wekvet6f	127	4	not	not	RB
cord-322516-wekvet6f	127	5	have	have	VB
cord-322516-wekvet6f	127	6	access	access	NN
cord-322516-wekvet6f	127	7	to	to	IN
cord-322516-wekvet6f	127	8	antibodies	antibody	NNS
cord-322516-wekvet6f	127	9	that	that	WDT
cord-322516-wekvet6f	127	10	crossreact	crossreact	VBP
cord-322516-wekvet6f	127	11	with	with	IN
cord-322516-wekvet6f	127	12	known	know	VBN
cord-322516-wekvet6f	127	13	markers	marker	NNS
cord-322516-wekvet6f	127	14	in	in	IN
cord-322516-wekvet6f	127	15	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	127	16	cells	cell	NNS
cord-322516-wekvet6f	127	17	,	,	,
cord-322516-wekvet6f	127	18	we	-PRON-	PRP
cord-322516-wekvet6f	127	19	examined	examine	VBD
cord-322516-wekvet6f	127	20	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	127	21	in	in	IN
cord-322516-wekvet6f	127	22	Vero	Vero	NNP
cord-322516-wekvet6f	127	23	cells	cell	NNS
cord-322516-wekvet6f	127	24	.	.	.
cord-322516-wekvet6f	128	1	IBV	IBV	NNP
cord-322516-wekvet6f	128	2	M	M	NNP
cord-322516-wekvet6f	128	3	localizes	localize	VBZ
cord-322516-wekvet6f	128	4	to	to	IN
cord-322516-wekvet6f	128	5	the	the	DT
cord-322516-wekvet6f	128	6	CGN	CGN	NNP
cord-322516-wekvet6f	128	7	in	in	IN
cord-322516-wekvet6f	128	8	these	these	DT
cord-322516-wekvet6f	128	9	cells	cell	NNS
cord-322516-wekvet6f	128	10	and	and	CC
cord-322516-wekvet6f	128	11	is	be	VBZ
cord-322516-wekvet6f	128	12	also	also	RB
cord-322516-wekvet6f	128	13	redistributed	redistribute	VBN
cord-322516-wekvet6f	128	14	to	to	IN
cord-322516-wekvet6f	128	15	the	the	DT
cord-322516-wekvet6f	128	16	ER	ER	NNP
cord-322516-wekvet6f	128	17	by	by	IN
cord-322516-wekvet6f	128	18	PDMP	PDMP	NNP
cord-322516-wekvet6f	128	19	(	(	-LRB-
cord-322516-wekvet6f	128	20	data	datum	NNS
cord-322516-wekvet6f	128	21	not	not	RB
cord-322516-wekvet6f	128	22	shown	show	VBN
cord-322516-wekvet6f	128	23	)	)	-RRB-
cord-322516-wekvet6f	128	24	.	.	.
cord-322516-wekvet6f	129	1	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	129	2	is	be	VBZ
cord-322516-wekvet6f	129	3	an	an	DT
cord-322516-wekvet6f	129	4	IC	IC	NNP
cord-322516-wekvet6f	129	5	protein	protein	NN
cord-322516-wekvet6f	129	6	that	that	IN
cord-322516-wekvet6f	129	7	cycles	cycle	NNS
cord-322516-wekvet6f	129	8	between	between	IN
cord-322516-wekvet6f	129	9	the	the	DT
cord-322516-wekvet6f	129	10	ER	ER	NNP
cord-322516-wekvet6f	129	11	,	,	,
cord-322516-wekvet6f	129	12	IC	IC	NNP
cord-322516-wekvet6f	129	13	,	,	,
cord-322516-wekvet6f	129	14	and	and	CC
cord-322516-wekvet6f	129	15	Golgi	Golgi	NNP
cord-322516-wekvet6f	129	16	stack	stack	NN
cord-322516-wekvet6f	129	17	(	(	-LRB-
cord-322516-wekvet6f	129	18	Lippincott	Lippincott	NNP
cord-322516-wekvet6f	129	19	-	-	HYPH
cord-322516-wekvet6f	129	20	Schwartz	Schwartz	NNP
cord-322516-wekvet6f	129	21	et	et	NNP
cord-322516-wekvet6f	129	22	al	al	NNP
cord-322516-wekvet6f	129	23	.	.	NNP
cord-322516-wekvet6f	129	24	,	,	,
cord-322516-wekvet6f	129	25	1990	1990	CD
cord-322516-wekvet6f	129	26	;	;	:
cord-322516-wekvet6f	129	27	Schindler	Schindler	NNP
cord-322516-wekvet6f	129	28	et	et	NNP
cord-322516-wekvet6f	129	29	al	al	NNP
cord-322516-wekvet6f	129	30	.	.	NNP
cord-322516-wekvet6f	129	31	,	,	,
cord-322516-wekvet6f	129	32	1993	1993	CD
cord-322516-wekvet6f	129	33	)	)	-RRB-
cord-322516-wekvet6f	129	34	.	.	.
cord-322516-wekvet6f	130	1	Vero	Vero	NNP
cord-322516-wekvet6f	130	2	cells	cell	NNS
cord-322516-wekvet6f	130	3	were	be	VBD
cord-322516-wekvet6f	130	4	treated	treat	VBN
cord-322516-wekvet6f	130	5	with	with	IN
cord-322516-wekvet6f	130	6	50	50	CD
cord-322516-wekvet6f	130	7	g	g	NN
cord-322516-wekvet6f	130	8	/	/	SYM
cord-322516-wekvet6f	130	9	ml	ml	NN
cord-322516-wekvet6f	130	10	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	130	11	for	for	IN
cord-322516-wekvet6f	130	12	1	1	CD
cord-322516-wekvet6f	130	13	h.	h.	NN
cord-322516-wekvet6f	130	14	PDMP	PDMP	NNP
cord-322516-wekvet6f	130	15	(	(	-LRB-
cord-322516-wekvet6f	130	16	100	100	CD
cord-322516-wekvet6f	130	17	M	M	NNP
cord-322516-wekvet6f	130	18	)	)	-RRB-
cord-322516-wekvet6f	130	19	was	be	VBD
cord-322516-wekvet6f	130	20	added	add	VBN
cord-322516-wekvet6f	130	21	,	,	,
cord-322516-wekvet6f	130	22	and	and	CC
cord-322516-wekvet6f	130	23	dishes	dish	NNS
cord-322516-wekvet6f	130	24	were	be	VBD
cord-322516-wekvet6f	130	25	fixed	fix	VBN
cord-322516-wekvet6f	130	26	at	at	IN
cord-322516-wekvet6f	130	27	the	the	DT
cord-322516-wekvet6f	130	28	indicated	indicate	VBN
cord-322516-wekvet6f	130	29	times	time	NNS
cord-322516-wekvet6f	130	30	and	and	CC
cord-322516-wekvet6f	130	31	prepared	prepare	VBN
cord-322516-wekvet6f	130	32	for	for	IN
cord-322516-wekvet6f	130	33	indirect	indirect	JJ
cord-322516-wekvet6f	130	34	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	130	35	.	.	.
cord-322516-wekvet6f	131	1	After	after	IN
cord-322516-wekvet6f	131	2	1	1	CD
cord-322516-wekvet6f	131	3	h	h	NN
cord-322516-wekvet6f	131	4	in	in	IN
cord-322516-wekvet6f	131	5	PDMP	PDMP	NNP
cord-322516-wekvet6f	131	6	,	,	,
cord-322516-wekvet6f	131	7	the	the	DT
cord-322516-wekvet6f	131	8	remaining	remain	VBG
cord-322516-wekvet6f	131	9	dishes	dish	NNS
cord-322516-wekvet6f	131	10	were	be	VBD
cord-322516-wekvet6f	131	11	washed	wash	VBN
cord-322516-wekvet6f	131	12	three	three	CD
cord-322516-wekvet6f	131	13	times	time	NNS
cord-322516-wekvet6f	131	14	with	with	IN
cord-322516-wekvet6f	131	15	1	1	CD
cord-322516-wekvet6f	131	16	ml	ml	NN
cord-322516-wekvet6f	131	17	DME	DME	NNP
cord-322516-wekvet6f	131	18	with	with	IN
cord-322516-wekvet6f	131	19	serum	serum	NN
cord-322516-wekvet6f	131	20	and	and	CC
cord-322516-wekvet6f	131	21	incubated	incubate	VBN
cord-322516-wekvet6f	131	22	with	with	IN
cord-322516-wekvet6f	131	23	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	131	24	-	-	HYPH
cord-322516-wekvet6f	131	25	containing	contain	VBG
cord-322516-wekvet6f	131	26	medium	medium	NN
cord-322516-wekvet6f	131	27	for	for	IN
cord-322516-wekvet6f	131	28	the	the	DT
cord-322516-wekvet6f	131	29	indicated	indicate	VBN
cord-322516-wekvet6f	131	30	time	time	NN
cord-322516-wekvet6f	131	31	before	before	IN
cord-322516-wekvet6f	131	32	being	be	VBG
cord-322516-wekvet6f	131	33	prepared	prepare	VBN
cord-322516-wekvet6f	131	34	for	for	IN
cord-322516-wekvet6f	131	35	indirect	indirect	JJ
cord-322516-wekvet6f	131	36	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	131	37	.	.	.
cord-322516-wekvet6f	132	1	For	for	IN
cord-322516-wekvet6f	132	2	each	each	DT
cord-322516-wekvet6f	132	3	experimental	experimental	JJ
cord-322516-wekvet6f	132	4	series	series	NN
cord-322516-wekvet6f	132	5	,	,	,
cord-322516-wekvet6f	132	6	the	the	DT
cord-322516-wekvet6f	132	7	Nomarski	Nomarski	NNP
cord-322516-wekvet6f	132	8	image	image	NN
cord-322516-wekvet6f	132	9	is	be	VBZ
cord-322516-wekvet6f	132	10	shown	show	VBN
cord-322516-wekvet6f	132	11	on	on	IN
cord-322516-wekvet6f	132	12	the	the	DT
cord-322516-wekvet6f	132	13	left	left	NN
cord-322516-wekvet6f	132	14	and	and	CC
cord-322516-wekvet6f	132	15	the	the	DT
cord-322516-wekvet6f	132	16	fluorescence	fluorescence	NN
cord-322516-wekvet6f	132	17	image	image	NN
cord-322516-wekvet6f	132	18	on	on	IN
cord-322516-wekvet6f	132	19	the	the	DT
cord-322516-wekvet6f	132	20	right	right	NN
cord-322516-wekvet6f	132	21	.	.	.
cord-322516-wekvet6f	133	1	Bar	bar	NN
cord-322516-wekvet6f	133	2	,	,	,
cord-322516-wekvet6f	133	3	10	10	CD
cord-322516-wekvet6f	133	4	m.	m.	NN
cord-322516-wekvet6f	133	5	with	with	IN
cord-322516-wekvet6f	133	6	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	133	7	for	for	IN
cord-322516-wekvet6f	133	8	1	1	CD
cord-322516-wekvet6f	133	9	h	h	NN
cord-322516-wekvet6f	134	1	and	and	CC
cord-322516-wekvet6f	134	2	then	then	RB
cord-322516-wekvet6f	134	3	with	with	IN
cord-322516-wekvet6f	134	4	or	or	CC
cord-322516-wekvet6f	134	5	without	without	IN
cord-322516-wekvet6f	134	6	100	100	CD
cord-322516-wekvet6f	134	7	M	m	NN
cord-322516-wekvet6f	134	8	PDMP	PDMP	NNP
cord-322516-wekvet6f	135	1	for	for	IN
cord-322516-wekvet6f	135	2	an	an	DT
cord-322516-wekvet6f	135	3	additional	additional	JJ
cord-322516-wekvet6f	135	4	hour	hour	NN
cord-322516-wekvet6f	135	5	before	before	IN
cord-322516-wekvet6f	135	6	being	be	VBG
cord-322516-wekvet6f	135	7	fixed	fix	VBN
cord-322516-wekvet6f	135	8	and	and	CC
cord-322516-wekvet6f	135	9	prepared	prepare	VBN
cord-322516-wekvet6f	135	10	for	for	IN
cord-322516-wekvet6f	135	11	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	135	12	(	(	-LRB-
cord-322516-wekvet6f	135	13	Fig	Fig	NNP
cord-322516-wekvet6f	135	14	.	.	.
cord-322516-wekvet6f	135	15	5	5	CD
cord-322516-wekvet6f	135	16	)	)	-RRB-
cord-322516-wekvet6f	135	17	.	.	.
cord-322516-wekvet6f	136	1	Similar	similar	JJ
cord-322516-wekvet6f	136	2	to	to	IN
cord-322516-wekvet6f	136	3	the	the	DT
cord-322516-wekvet6f	136	4	effects	effect	NNS
cord-322516-wekvet6f	136	5	on	on	IN
cord-322516-wekvet6f	136	6	IBV	IBV	NNP
cord-322516-wekvet6f	136	7	M	M	NNP
cord-322516-wekvet6f	136	8	,	,	,
cord-322516-wekvet6f	136	9	PDMP	PDMP	NNP
cord-322516-wekvet6f	136	10	treatment	treatment	NN
cord-322516-wekvet6f	136	11	shifted	shift	VBD
cord-322516-wekvet6f	136	12	the	the	DT
cord-322516-wekvet6f	136	13	steady	steady	JJ
cord-322516-wekvet6f	136	14	-	-	HYPH
cord-322516-wekvet6f	136	15	state	state	NN
cord-322516-wekvet6f	136	16	distribution	distribution	NN
cord-322516-wekvet6f	136	17	of	of	IN
cord-322516-wekvet6f	136	18	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	136	19	to	to	IN
cord-322516-wekvet6f	136	20	the	the	DT
cord-322516-wekvet6f	136	21	ER	ER	NNP
cord-322516-wekvet6f	136	22	.	.	.
cord-322516-wekvet6f	137	1	In	in	IN
cord-322516-wekvet6f	137	2	addition	addition	NN
cord-322516-wekvet6f	137	3	,	,	,
cord-322516-wekvet6f	137	4	neither	neither	CC
cord-322516-wekvet6f	137	5	␤	␤	NNP
cord-322516-wekvet6f	137	6	CA	CA	NNP
cord-322516-wekvet6f	137	7	nor	nor	CC
cord-322516-wekvet6f	137	8	FB1	FB1	NNP
cord-322516-wekvet6f	137	9	had	have	VBD
cord-322516-wekvet6f	137	10	any	any	DT
cord-322516-wekvet6f	137	11	effect	effect	NN
cord-322516-wekvet6f	137	12	on	on	IN
cord-322516-wekvet6f	137	13	the	the	DT
cord-322516-wekvet6f	137	14	localization	localization	NN
cord-322516-wekvet6f	137	15	of	of	IN
cord-322516-wekvet6f	137	16	ER	ER	NNP
cord-322516-wekvet6f	137	17	-	-	HYPH
cord-322516-wekvet6f	137	18	GIC-53	GIC-53	NNP
cord-322516-wekvet6f	138	1	(	(	-LRB-
cord-322516-wekvet6f	138	2	data	datum	NNS
cord-322516-wekvet6f	138	3	not	not	RB
cord-322516-wekvet6f	138	4	shown	show	VBN
cord-322516-wekvet6f	138	5	)	)	-RRB-
cord-322516-wekvet6f	138	6	.	.	.
cord-322516-wekvet6f	139	1	The	the	DT
cord-322516-wekvet6f	139	2	above	above	JJ
cord-322516-wekvet6f	139	3	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	139	4	results	result	NNS
cord-322516-wekvet6f	139	5	suggested	suggest	VBD
cord-322516-wekvet6f	139	6	that	that	IN
cord-322516-wekvet6f	139	7	PDMP	PDMP	NNP
cord-322516-wekvet6f	139	8	might	may	MD
cord-322516-wekvet6f	139	9	generally	generally	RB
cord-322516-wekvet6f	139	10	alter	alter	VB
cord-322516-wekvet6f	139	11	the	the	DT
cord-322516-wekvet6f	139	12	distribution	distribution	NN
cord-322516-wekvet6f	139	13	of	of	IN
cord-322516-wekvet6f	139	14	proteins	protein	NNS
cord-322516-wekvet6f	139	15	that	that	WDT
cord-322516-wekvet6f	139	16	have	have	VBP
cord-322516-wekvet6f	139	17	a	a	DT
cord-322516-wekvet6f	139	18	dynamic	dynamic	JJ
cord-322516-wekvet6f	139	19	localization	localization	NN
cord-322516-wekvet6f	139	20	mechanism	mechanism	NN
cord-322516-wekvet6f	139	21	.	.	.
cord-322516-wekvet6f	140	1	Interestingly	interestingly	RB
cord-322516-wekvet6f	140	2	,	,	,
cord-322516-wekvet6f	140	3	it	-PRON-	PRP
cord-322516-wekvet6f	140	4	has	have	VBZ
cord-322516-wekvet6f	140	5	been	be	VBN
cord-322516-wekvet6f	140	6	shown	show	VBN
cord-322516-wekvet6f	140	7	that	that	IN
cord-322516-wekvet6f	140	8	PDMP	PDMP	NNP
cord-322516-wekvet6f	140	9	slows	slow	VBZ
cord-322516-wekvet6f	140	10	the	the	DT
cord-322516-wekvet6f	140	11	rate	rate	NN
cord-322516-wekvet6f	140	12	of	of	IN
cord-322516-wekvet6f	140	13	both	both	DT
cord-322516-wekvet6f	140	14	anterograde	anterograde	JJ
cord-322516-wekvet6f	140	15	vesicular	vesicular	JJ
cord-322516-wekvet6f	140	16	traffic	traffic	NN
cord-322516-wekvet6f	141	1	(	(	-LRB-
cord-322516-wekvet6f	141	2	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	141	3	et	et	NNP
cord-322516-wekvet6f	141	4	al	al	NNP
cord-322516-wekvet6f	141	5	.	.	NNP
cord-322516-wekvet6f	141	6	,	,	,
cord-322516-wekvet6f	141	7	1992	1992	CD
cord-322516-wekvet6f	141	8	)	)	-RRB-
cord-322516-wekvet6f	141	9	and	and	CC
cord-322516-wekvet6f	141	10	endocytosis	endocytosis	NN
cord-322516-wekvet6f	142	1	(	(	-LRB-
cord-322516-wekvet6f	142	2	Chen	Chen	NNP
cord-322516-wekvet6f	142	3	et	et	NNP
cord-322516-wekvet6f	142	4	al	al	NNP
cord-322516-wekvet6f	142	5	.	.	NNP
cord-322516-wekvet6f	142	6	,	,	,
cord-322516-wekvet6f	142	7	1995	1995	CD
cord-322516-wekvet6f	142	8	)	)	-RRB-
cord-322516-wekvet6f	142	9	in	in	IN
cord-322516-wekvet6f	142	10	CHO	CHO	NNP
cord-322516-wekvet6f	142	11	cells	cell	NNS
cord-322516-wekvet6f	142	12	.	.	.
cord-322516-wekvet6f	143	1	We	-PRON-	PRP
cord-322516-wekvet6f	143	2	tested	test	VBD
cord-322516-wekvet6f	143	3	whether	whether	IN
cord-322516-wekvet6f	143	4	PDMP	PDMP	NNP
cord-322516-wekvet6f	143	5	also	also	RB
cord-322516-wekvet6f	143	6	slowed	slow	VBD
cord-322516-wekvet6f	143	7	anterograde	anterograde	JJ
cord-322516-wekvet6f	143	8	traffic	traffic	NN
cord-322516-wekvet6f	143	9	in	in	IN
cord-322516-wekvet6f	143	10	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	143	11	cells	cell	NNS
cord-322516-wekvet6f	143	12	.	.	.
cord-322516-wekvet6f	144	1	We	-PRON-	PRP
cord-322516-wekvet6f	144	2	used	use	VBD
cord-322516-wekvet6f	144	3	a	a	DT
cord-322516-wekvet6f	144	4	plasma	plasma	NN
cord-322516-wekvet6f	144	5	membrane	membrane	NN
cord-322516-wekvet6f	144	6	protein	protein	NN
cord-322516-wekvet6f	144	7	,	,	,
cord-322516-wekvet6f	144	8	the	the	DT
cord-322516-wekvet6f	144	9	well	well	RB
cord-322516-wekvet6f	144	10	-	-	HYPH
cord-322516-wekvet6f	144	11	characterized	characterize	VBN
cord-322516-wekvet6f	144	12	G	g	NN
cord-322516-wekvet6f	144	13	protein	protein	NN
cord-322516-wekvet6f	144	14	from	from	IN
cord-322516-wekvet6f	144	15	VSV	VSV	NNP
cord-322516-wekvet6f	144	16	.	.	.
cord-322516-wekvet6f	145	1	A	a	DT
cord-322516-wekvet6f	145	2	pulse	pulse	NN
cord-322516-wekvet6f	145	3	-	-	HYPH
cord-322516-wekvet6f	145	4	chase	chase	NN
cord-322516-wekvet6f	145	5	experiment	experiment	NN
cord-322516-wekvet6f	145	6	was	be	VBD
cord-322516-wekvet6f	145	7	performed	perform	VBN
cord-322516-wekvet6f	145	8	either	either	CC
cord-322516-wekvet6f	145	9	in	in	IN
cord-322516-wekvet6f	145	10	the	the	DT
cord-322516-wekvet6f	145	11	presence	presence	NN
cord-322516-wekvet6f	145	12	or	or	CC
cord-322516-wekvet6f	145	13	absence	absence	NN
cord-322516-wekvet6f	145	14	of	of	IN
cord-322516-wekvet6f	145	15	PDMP	PDMP	NNP
cord-322516-wekvet6f	145	16	,	,	,
cord-322516-wekvet6f	145	17	␤	␤	NNP
cord-322516-wekvet6f	145	18	CA	CA	NNP
cord-322516-wekvet6f	145	19	,	,	,
cord-322516-wekvet6f	145	20	or	or	CC
cord-322516-wekvet6f	145	21	FB1	FB1	NNP
cord-322516-wekvet6f	145	22	.	.	.
cord-322516-wekvet6f	146	1	The	the	DT
cord-322516-wekvet6f	146	2	rate	rate	NN
cord-322516-wekvet6f	146	3	of	of	IN
cord-322516-wekvet6f	146	4	accumulation	accumulation	NN
cord-322516-wekvet6f	146	5	of	of	IN
cord-322516-wekvet6f	146	6	endo	endo	NN
cord-322516-wekvet6f	146	7	H	H	NNP
cord-322516-wekvet6f	146	8	-	-	HYPH
cord-322516-wekvet6f	146	9	resistant	resistant	JJ
cord-322516-wekvet6f	146	10	VSV	VSV	NNP
cord-322516-wekvet6f	146	11	G	G	NNP
cord-322516-wekvet6f	146	12	was	be	VBD
cord-322516-wekvet6f	146	13	used	use	VBN
cord-322516-wekvet6f	146	14	as	as	IN
cord-322516-wekvet6f	146	15	an	an	DT
cord-322516-wekvet6f	146	16	assay	assay	NN
cord-322516-wekvet6f	146	17	for	for	IN
cord-322516-wekvet6f	146	18	the	the	DT
cord-322516-wekvet6f	146	19	rate	rate	NN
cord-322516-wekvet6f	146	20	of	of	IN
cord-322516-wekvet6f	146	21	arrival	arrival	NN
cord-322516-wekvet6f	146	22	at	at	IN
cord-322516-wekvet6f	146	23	the	the	DT
cord-322516-wekvet6f	146	24	medial	medial	NN
cord-322516-wekvet6f	146	25	-Golgi	-golgi	NN
cord-322516-wekvet6f	146	26	.	.	.
cord-322516-wekvet6f	147	1	Neither	neither	CC
cord-322516-wekvet6f	147	2	␤	␤	.
cord-322516-wekvet6f	148	1	CA	CA	NNP
cord-322516-wekvet6f	148	2	nor	nor	CC
cord-322516-wekvet6f	148	3	FB1	FB1	NNP
cord-322516-wekvet6f	148	4	had	have	VBD
cord-322516-wekvet6f	148	5	any	any	DT
cord-322516-wekvet6f	148	6	effect	effect	NN
cord-322516-wekvet6f	148	7	on	on	IN
cord-322516-wekvet6f	148	8	the	the	DT
cord-322516-wekvet6f	148	9	rate	rate	NN
cord-322516-wekvet6f	148	10	of	of	IN
cord-322516-wekvet6f	148	11	anterograde	anterograde	JJ
cord-322516-wekvet6f	148	12	traffic	traffic	NN
cord-322516-wekvet6f	148	13	.	.	.
cord-322516-wekvet6f	149	1	However	however	RB
cord-322516-wekvet6f	149	2	,	,	,
cord-322516-wekvet6f	149	3	PDMP	PDMP	NNP
cord-322516-wekvet6f	149	4	increased	increase	VBD
cord-322516-wekvet6f	149	5	the	the	DT
cord-322516-wekvet6f	149	6	halftime	halftime	NN
cord-322516-wekvet6f	149	7	for	for	IN
cord-322516-wekvet6f	149	8	transport	transport	NN
cord-322516-wekvet6f	149	9	by	by	IN
cord-322516-wekvet6f	149	10	‫ف‬	‫ف‬	NNP
cord-322516-wekvet6f	149	11	2.5-fold	2.5-fold	CD
cord-322516-wekvet6f	149	12	from	from	IN
cord-322516-wekvet6f	149	13	18	18	CD
cord-322516-wekvet6f	149	14	to	to	TO
cord-322516-wekvet6f	149	15	44	44	CD
cord-322516-wekvet6f	149	16	min	min	NN
cord-322516-wekvet6f	149	17	(	(	-LRB-
cord-322516-wekvet6f	149	18	Fig	Fig	NNP
cord-322516-wekvet6f	149	19	.	.	.
cord-322516-wekvet6f	149	20	6	6	CD
cord-322516-wekvet6f	149	21	)	)	-RRB-
cord-322516-wekvet6f	149	22	.	.	.
cord-322516-wekvet6f	150	1	Fig	Fig	NNP
cord-322516-wekvet6f	150	2	.	.	NNP
cord-322516-wekvet6f	150	3	6	6	CD
cord-322516-wekvet6f	150	4	shows	show	VBZ
cord-322516-wekvet6f	150	5	that	that	IN
cord-322516-wekvet6f	150	6	neither	neither	CC
cord-322516-wekvet6f	150	7	␤	␤	NNP
cord-322516-wekvet6f	150	8	CA	CA	NNP
cord-322516-wekvet6f	150	9	nor	nor	CC
cord-322516-wekvet6f	150	10	FB1	FB1	NNP
cord-322516-wekvet6f	150	11	had	have	VBD
cord-322516-wekvet6f	150	12	any	any	DT
cord-322516-wekvet6f	150	13	effect	effect	NN
cord-322516-wekvet6f	150	14	on	on	IN
cord-322516-wekvet6f	150	15	the	the	DT
cord-322516-wekvet6f	150	16	transit	transit	NN
cord-322516-wekvet6f	150	17	rate	rate	NN
cord-322516-wekvet6f	150	18	of	of	IN
cord-322516-wekvet6f	150	19	VSV	VSV	NNP
cord-322516-wekvet6f	150	20	G	G	NNP
cord-322516-wekvet6f	150	21	,	,	,
cord-322516-wekvet6f	150	22	suggesting	suggest	VBG
cord-322516-wekvet6f	150	23	that	that	IN
cord-322516-wekvet6f	150	24	the	the	DT
cord-322516-wekvet6f	150	25	decreased	decrease	VBN
cord-322516-wekvet6f	150	26	rate	rate	NN
cord-322516-wekvet6f	150	27	with	with	IN
cord-322516-wekvet6f	150	28	PDMP	PDMP	NNP
cord-322516-wekvet6f	150	29	was	be	VBD
cord-322516-wekvet6f	150	30	not	not	RB
cord-322516-wekvet6f	150	31	due	due	JJ
cord-322516-wekvet6f	150	32	to	to	IN
cord-322516-wekvet6f	150	33	a	a	DT
cord-322516-wekvet6f	150	34	block	block	NN
cord-322516-wekvet6f	150	35	in	in	IN
cord-322516-wekvet6f	150	36	the	the	DT
cord-322516-wekvet6f	150	37	ongoing	ongoing	JJ
cord-322516-wekvet6f	150	38	synthesis	synthesis	NN
cord-322516-wekvet6f	150	39	of	of	IN
cord-322516-wekvet6f	150	40	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	150	41	.	.	.
cord-322516-wekvet6f	151	1	PDMP	PDMP	NNP
cord-322516-wekvet6f	151	2	inhibits	inhibit	VBZ
cord-322516-wekvet6f	151	3	the	the	DT
cord-322516-wekvet6f	151	4	conversion	conversion	NN
cord-322516-wekvet6f	151	5	of	of	IN
cord-322516-wekvet6f	151	6	ceramide	ceramide	NN
cord-322516-wekvet6f	151	7	into	into	IN
cord-322516-wekvet6f	151	8	glycosphingolipids	glycosphingolipid	NNS
cord-322516-wekvet6f	151	9	and	and	CC
cord-322516-wekvet6f	151	10	sphingomyelin	sphingomyelin	NN
cord-322516-wekvet6f	151	11	.	.	.
cord-322516-wekvet6f	152	1	One	one	CD
cord-322516-wekvet6f	152	2	possible	possible	JJ
cord-322516-wekvet6f	152	3	explanation	explanation	NN
cord-322516-wekvet6f	152	4	for	for	IN
cord-322516-wekvet6f	152	5	the	the	DT
cord-322516-wekvet6f	152	6	effects	effect	NNS
cord-322516-wekvet6f	152	7	observed	observe	VBN
cord-322516-wekvet6f	152	8	with	with	IN
cord-322516-wekvet6f	152	9	PDMP	PDMP	NNP
cord-322516-wekvet6f	152	10	was	be	VBD
cord-322516-wekvet6f	152	11	an	an	DT
cord-322516-wekvet6f	152	12	accumulation	accumulation	NN
cord-322516-wekvet6f	152	13	of	of	IN
cord-322516-wekvet6f	152	14	the	the	DT
cord-322516-wekvet6f	152	15	precursor	precursor	NN
cord-322516-wekvet6f	152	16	ceramide	ceramide	NN
cord-322516-wekvet6f	152	17	.	.	.
cord-322516-wekvet6f	153	1	␤	␤	.
cord-322516-wekvet6f	154	1	CA	CA	NNP
cord-322516-wekvet6f	154	2	and	and	CC
cord-322516-wekvet6f	154	3	FB1	FB1	NNP
cord-322516-wekvet6f	154	4	act	act	NNP
cord-322516-wekvet6f	154	5	upstream	upstream	RB
cord-322516-wekvet6f	154	6	of	of	IN
cord-322516-wekvet6f	154	7	PDMP	PDMP	NNP
cord-322516-wekvet6f	154	8	(	(	-LRB-
cord-322516-wekvet6f	154	9	Fig	Fig	NNP
cord-322516-wekvet6f	154	10	.	.	.
cord-322516-wekvet6f	154	11	1	1	CD
cord-322516-wekvet6f	154	12	)	)	-RRB-
cord-322516-wekvet6f	154	13	,	,	,
cord-322516-wekvet6f	154	14	and	and	CC
cord-322516-wekvet6f	154	15	the	the	DT
cord-322516-wekvet6f	154	16	intermediates	intermediate	NNS
cord-322516-wekvet6f	154	17	in	in	IN
cord-322516-wekvet6f	154	18	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	154	19	synthesis	synthesis	NN
cord-322516-wekvet6f	154	20	between	between	IN
cord-322516-wekvet6f	154	21	these	these	DT
cord-322516-wekvet6f	154	22	steps	step	NNS
cord-322516-wekvet6f	154	23	and	and	CC
cord-322516-wekvet6f	154	24	ceramide	ceramide	NN
cord-322516-wekvet6f	154	25	production	production	NN
cord-322516-wekvet6f	154	26	are	be	VBP
cord-322516-wekvet6f	154	27	thought	think	VBN
cord-322516-wekvet6f	154	28	to	to	TO
cord-322516-wekvet6f	154	29	be	be	VB
cord-322516-wekvet6f	154	30	short	short	RB
cord-322516-wekvet6f	154	31	lived	live	VBN
cord-322516-wekvet6f	154	32	(	(	-LRB-
cord-322516-wekvet6f	154	33	Merrill	Merrill	NNP
cord-322516-wekvet6f	154	34	and	and	CC
cord-322516-wekvet6f	154	35	Wang	Wang	NNP
cord-322516-wekvet6f	154	36	,	,	,
cord-322516-wekvet6f	154	37	1986	1986	CD
cord-322516-wekvet6f	154	38	;	;	:
cord-322516-wekvet6f	154	39	Medlock	Medlock	NNP
cord-322516-wekvet6f	154	40	and	and	CC
cord-322516-wekvet6f	154	41	Merril	Merril	NNP
cord-322516-wekvet6f	154	42	,	,	,
cord-322516-wekvet6f	154	43	1988	1988	CD
cord-322516-wekvet6f	154	44	)	)	-RRB-
cord-322516-wekvet6f	154	45	.	.	.
cord-322516-wekvet6f	155	1	To	to	TO
cord-322516-wekvet6f	155	2	ask	ask	VB
cord-322516-wekvet6f	155	3	if	if	IN
cord-322516-wekvet6f	155	4	ceramide	ceramide	NN
cord-322516-wekvet6f	155	5	accumulation	accumulation	NN
cord-322516-wekvet6f	155	6	might	may	MD
cord-322516-wekvet6f	155	7	mediate	mediate	VB
cord-322516-wekvet6f	155	8	the	the	DT
cord-322516-wekvet6f	155	9	PDMP	PDMP	NNP
cord-322516-wekvet6f	155	10	-	-	HYPH
cord-322516-wekvet6f	155	11	induced	induce	VBN
cord-322516-wekvet6f	155	12	slowing	slowing	NN
cord-322516-wekvet6f	155	13	of	of	IN
cord-322516-wekvet6f	155	14	anterograde	anterograde	JJ
cord-322516-wekvet6f	155	15	traffic	traffic	NN
cord-322516-wekvet6f	155	16	,	,	,
cord-322516-wekvet6f	155	17	cells	cell	NNS
cord-322516-wekvet6f	155	18	were	be	VBD
cord-322516-wekvet6f	155	19	treated	treat	VBN
cord-322516-wekvet6f	155	20	with	with	IN
cord-322516-wekvet6f	155	21	␤	␤	NNP
cord-322516-wekvet6f	155	22	CA	CA	NNP
cord-322516-wekvet6f	155	23	or	or	CC
cord-322516-wekvet6f	155	24	FB1	fb1	NN
cord-322516-wekvet6f	155	25	before	before	IN
cord-322516-wekvet6f	155	26	PDMP	PDMP	NNP
cord-322516-wekvet6f	155	27	.	.	.
cord-322516-wekvet6f	156	1	We	-PRON-	PRP
cord-322516-wekvet6f	156	2	performed	perform	VBD
cord-322516-wekvet6f	156	3	a	a	DT
cord-322516-wekvet6f	156	4	pulse	pulse	NN
cord-322516-wekvet6f	156	5	-	-	HYPH
cord-322516-wekvet6f	156	6	chase	chase	NN
cord-322516-wekvet6f	156	7	labeling	labeling	NN
cord-322516-wekvet6f	156	8	experiment	experiment	NN
cord-322516-wekvet6f	156	9	with	with	IN
cord-322516-wekvet6f	156	10	cells	cell	NNS
cord-322516-wekvet6f	156	11	pretreated	pretreate	VBN
cord-322516-wekvet6f	156	12	with	with	IN
cord-322516-wekvet6f	156	13	either	either	DT
cord-322516-wekvet6f	156	14	␤	␤	NNP
cord-322516-wekvet6f	156	15	CA	CA	NNP
cord-322516-wekvet6f	156	16	or	or	CC
cord-322516-wekvet6f	156	17	FB1	FB1	NNP
cord-322516-wekvet6f	156	18	for	for	IN
cord-322516-wekvet6f	156	19	1	1	CD
cord-322516-wekvet6f	156	20	h	h	NN
cord-322516-wekvet6f	156	21	before	before	IN
cord-322516-wekvet6f	156	22	being	be	VBG
cord-322516-wekvet6f	156	23	chased	chase	VBN
cord-322516-wekvet6f	156	24	in	in	IN
cord-322516-wekvet6f	156	25	the	the	DT
cord-322516-wekvet6f	156	26	presence	presence	NN
cord-322516-wekvet6f	156	27	or	or	CC
cord-322516-wekvet6f	156	28	absence	absence	NN
cord-322516-wekvet6f	156	29	of	of	IN
cord-322516-wekvet6f	156	30	␤	␤	``
cord-322516-wekvet6f	156	31	CA	CA	NNP
cord-322516-wekvet6f	156	32	or	or	CC
cord-322516-wekvet6f	156	33	FB1	FB1	NNP
cord-322516-wekvet6f	156	34	and	and	CC
cord-322516-wekvet6f	156	35	PDMP	PDMP	NNP
cord-322516-wekvet6f	156	36	(	(	-LRB-
cord-322516-wekvet6f	156	37	Fig	Fig	NNP
cord-322516-wekvet6f	156	38	.	.	.
cord-322516-wekvet6f	156	39	6	6	CD
cord-322516-wekvet6f	156	40	)	)	-RRB-
cord-322516-wekvet6f	156	41	.	.	.
cord-322516-wekvet6f	157	1	Pretreatment	pretreatment	JJ
cord-322516-wekvet6f	157	2	with	with	IN
cord-322516-wekvet6f	157	3	the	the	DT
cord-322516-wekvet6f	157	4	earlier	early	JJR
cord-322516-wekvet6f	157	5	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	157	6	reduced	reduce	VBD
cord-322516-wekvet6f	157	7	the	the	DT
cord-322516-wekvet6f	157	8	PDMP	PDMP	NNP
cord-322516-wekvet6f	157	9	-	-	HYPH
cord-322516-wekvet6f	157	10	induced	induce	VBN
cord-322516-wekvet6f	157	11	slowing	slowing	NN
cord-322516-wekvet6f	157	12	of	of	IN
cord-322516-wekvet6f	157	13	anterograde	anterograde	JJ
cord-322516-wekvet6f	157	14	traffic	traffic	NN
cord-322516-wekvet6f	157	15	by	by	IN
cord-322516-wekvet6f	157	16	about	about	RB
cord-322516-wekvet6f	157	17	half	half	NN
cord-322516-wekvet6f	157	18	,	,	,
cord-322516-wekvet6f	157	19	suggesting	suggest	VBG
cord-322516-wekvet6f	157	20	that	that	IN
cord-322516-wekvet6f	157	21	accumulation	accumulation	NN
cord-322516-wekvet6f	157	22	of	of	IN
cord-322516-wekvet6f	157	23	newly	newly	RB
cord-322516-wekvet6f	157	24	synthesized	synthesize	VBN
cord-322516-wekvet6f	157	25	ceramide	ceramide	NN
cord-322516-wekvet6f	157	26	at	at	IN
cord-322516-wekvet6f	157	27	least	least	JJS
cord-322516-wekvet6f	157	28	partially	partially	RB
cord-322516-wekvet6f	157	29	mediates	mediate	VBZ
cord-322516-wekvet6f	157	30	this	this	DT
cord-322516-wekvet6f	157	31	effect	effect	NN
cord-322516-wekvet6f	157	32	.	.	.
cord-322516-wekvet6f	158	1	To	to	TO
cord-322516-wekvet6f	158	2	test	test	VB
cord-322516-wekvet6f	158	3	whether	whether	IN
cord-322516-wekvet6f	158	4	ceramide	ceramide	NN
cord-322516-wekvet6f	158	5	was	be	VBD
cord-322516-wekvet6f	158	6	likely	likely	JJ
cord-322516-wekvet6f	158	7	to	to	TO
cord-322516-wekvet6f	158	8	mediate	mediate	VB
cord-322516-wekvet6f	158	9	the	the	DT
cord-322516-wekvet6f	158	10	PDMPinduced	pdmpinduced	JJ
cord-322516-wekvet6f	158	11	mislocalization	mislocalization	NN
cord-322516-wekvet6f	158	12	of	of	IN
cord-322516-wekvet6f	158	13	IBV	IBV	NNP
cord-322516-wekvet6f	158	14	M	M	NNP
cord-322516-wekvet6f	158	15	,	,	,
cord-322516-wekvet6f	158	16	indirect	indirect	JJ
cord-322516-wekvet6f	158	17	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	158	18	was	be	VBD
cord-322516-wekvet6f	158	19	performed	perform	VBN
cord-322516-wekvet6f	158	20	as	as	IN
cord-322516-wekvet6f	158	21	above	above	RB
cord-322516-wekvet6f	158	22	with	with	IN
cord-322516-wekvet6f	158	23	cells	cell	NNS
cord-322516-wekvet6f	158	24	pretreated	pretreate	VBN
cord-322516-wekvet6f	158	25	with	with	IN
cord-322516-wekvet6f	158	26	either	either	DT
cord-322516-wekvet6f	158	27	␤	␤	NNP
cord-322516-wekvet6f	158	28	CA	CA	NNP
cord-322516-wekvet6f	158	29	or	or	CC
cord-322516-wekvet6f	158	30	FB1	FB1	NNP
cord-322516-wekvet6f	158	31	for	for	IN
cord-322516-wekvet6f	158	32	1	1	CD
cord-322516-wekvet6f	158	33	h	h	NN
cord-322516-wekvet6f	158	34	before	before	IN
cord-322516-wekvet6f	158	35	the	the	DT
cord-322516-wekvet6f	158	36	addition	addition	NN
cord-322516-wekvet6f	158	37	of	of	IN
cord-322516-wekvet6f	158	38	PDMP	PDMP	NNP
cord-322516-wekvet6f	158	39	.	.	.
cord-322516-wekvet6f	159	1	To	to	TO
cord-322516-wekvet6f	159	2	simplify	simplify	VB
cord-322516-wekvet6f	159	3	the	the	DT
cord-322516-wekvet6f	159	4	quantification	quantification	NN
cord-322516-wekvet6f	159	5	,	,	,
cord-322516-wekvet6f	159	6	the	the	DT
cord-322516-wekvet6f	159	7	localization	localization	NN
cord-322516-wekvet6f	159	8	of	of	IN
cord-322516-wekvet6f	159	9	IBV	IBV	NNP
cord-322516-wekvet6f	159	10	M	M	NNP
cord-322516-wekvet6f	159	11	was	be	VBD
cord-322516-wekvet6f	159	12	classified	classify	VBN
cord-322516-wekvet6f	159	13	into	into	IN
cord-322516-wekvet6f	159	14	one	one	CD
cord-322516-wekvet6f	159	15	of	of	IN
cord-322516-wekvet6f	159	16	three	three	CD
cord-322516-wekvet6f	159	17	staining	stain	VBG
cord-322516-wekvet6f	159	18	patterns	pattern	NNS
cord-322516-wekvet6f	159	19	.	.	.
cord-322516-wekvet6f	160	1	Class	class	NN
cord-322516-wekvet6f	160	2	1	1	CD
cord-322516-wekvet6f	160	3	was	be	VBD
cord-322516-wekvet6f	160	4	the	the	DT
cord-322516-wekvet6f	160	5	most	most	RBS
cord-322516-wekvet6f	160	6	commonly	commonly	RB
cord-322516-wekvet6f	160	7	seen	see	VBN
cord-322516-wekvet6f	160	8	pattern	pattern	NN
cord-322516-wekvet6f	160	9	in	in	IN
cord-322516-wekvet6f	160	10	untreated	untreated	JJ
cord-322516-wekvet6f	160	11	cells	cell	NNS
cord-322516-wekvet6f	160	12	,	,	,
cord-322516-wekvet6f	160	13	i.e.	i.e.	FW
cord-322516-wekvet6f	160	14	,	,	,
cord-322516-wekvet6f	160	15	tight	tight	JJ
cord-322516-wekvet6f	160	16	juxta	juxta	JJ
cord-322516-wekvet6f	160	17	-	-	HYPH
cord-322516-wekvet6f	160	18	nuclear	nuclear	JJ
cord-322516-wekvet6f	160	19	staining	staining	NN
cord-322516-wekvet6f	160	20	that	that	WDT
cord-322516-wekvet6f	160	21	colocalized	colocalize	VBN
cord-322516-wekvet6f	160	22	with	with	IN
cord-322516-wekvet6f	160	23	Golgi	Golgi	NNP
cord-322516-wekvet6f	160	24	markers	marker	NNS
cord-322516-wekvet6f	160	25	.	.	.
cord-322516-wekvet6f	161	1	Class	class	NN
cord-322516-wekvet6f	161	2	3	3	CD
cord-322516-wekvet6f	161	3	was	be	VBD
cord-322516-wekvet6f	161	4	the	the	DT
cord-322516-wekvet6f	161	5	most	most	RBS
cord-322516-wekvet6f	161	6	commonly	commonly	RB
cord-322516-wekvet6f	161	7	seen	see	VBN
cord-322516-wekvet6f	161	8	pattern	pattern	NN
cord-322516-wekvet6f	161	9	in	in	IN
cord-322516-wekvet6f	161	10	PDMP	PDMP	NNP
cord-322516-wekvet6f	161	11	-	-	HYPH
cord-322516-wekvet6f	161	12	treated	treat	VBN
cord-322516-wekvet6f	161	13	cells	cell	NNS
cord-322516-wekvet6f	161	14	,	,	,
cord-322516-wekvet6f	161	15	i.e.	i.e.	FW
cord-322516-wekvet6f	161	16	,	,	,
cord-322516-wekvet6f	161	17	diffuse	diffuse	VB
cord-322516-wekvet6f	161	18	staining	staining	NN
cord-322516-wekvet6f	161	19	with	with	IN
cord-322516-wekvet6f	161	20	prominent	prominent	JJ
cord-322516-wekvet6f	161	21	nuclear	nuclear	JJ
cord-322516-wekvet6f	161	22	envelope	envelope	NN
cord-322516-wekvet6f	161	23	staining	stain	VBG
cord-322516-wekvet6f	161	24	that	that	IN
cord-322516-wekvet6f	161	25	colocalized	colocalize	VBN
cord-322516-wekvet6f	161	26	with	with	IN
cord-322516-wekvet6f	161	27	ER	ER	NNP
cord-322516-wekvet6f	161	28	markers	marker	NNS
cord-322516-wekvet6f	161	29	.	.	.
cord-322516-wekvet6f	162	1	Class	class	NN
cord-322516-wekvet6f	162	2	2	2	CD
cord-322516-wekvet6f	162	3	was	be	VBD
cord-322516-wekvet6f	162	4	intermediate	intermediate	JJ
cord-322516-wekvet6f	162	5	between	between	IN
cord-322516-wekvet6f	162	6	the	the	DT
cord-322516-wekvet6f	162	7	class	class	NN
cord-322516-wekvet6f	162	8	1	1	CD
cord-322516-wekvet6f	162	9	and	and	CC
cord-322516-wekvet6f	162	10	class	class	NN
cord-322516-wekvet6f	162	11	3	3	CD
cord-322516-wekvet6f	162	12	.	.	.
cord-322516-wekvet6f	163	1	Whether	whether	IN
cord-322516-wekvet6f	163	2	this	this	DT
cord-322516-wekvet6f	163	3	pattern	pattern	NN
cord-322516-wekvet6f	163	4	represents	represent	VBZ
cord-322516-wekvet6f	163	5	an	an	DT
cord-322516-wekvet6f	163	6	overlap	overlap	NN
cord-322516-wekvet6f	163	7	of	of	IN
cord-322516-wekvet6f	163	8	ER	ER	NNP
cord-322516-wekvet6f	163	9	and	and	CC
cord-322516-wekvet6f	163	10	Golgi	Golgi	NNP
cord-322516-wekvet6f	163	11	staining	staining	NN
cord-322516-wekvet6f	163	12	patterns	pattern	NNS
cord-322516-wekvet6f	163	13	or	or	CC
cord-322516-wekvet6f	163	14	an	an	DT
cord-322516-wekvet6f	163	15	increase	increase	NN
cord-322516-wekvet6f	163	16	in	in	IN
cord-322516-wekvet6f	163	17	IC	IC	NNP
cord-322516-wekvet6f	163	18	staining	staining	NN
cord-322516-wekvet6f	163	19	is	be	VBZ
cord-322516-wekvet6f	163	20	not	not	RB
cord-322516-wekvet6f	163	21	clear	clear	JJ
cord-322516-wekvet6f	163	22	.	.	.
cord-322516-wekvet6f	164	1	For	for	IN
cord-322516-wekvet6f	164	2	these	these	DT
cord-322516-wekvet6f	164	3	experiments	experiment	NNS
cord-322516-wekvet6f	164	4	,	,	,
cord-322516-wekvet6f	164	5	coded	code	VBN
cord-322516-wekvet6f	164	6	samples	sample	NNS
cord-322516-wekvet6f	164	7	were	be	VBD
cord-322516-wekvet6f	164	8	quantified	quantify	VBN
cord-322516-wekvet6f	164	9	by	by	IN
cord-322516-wekvet6f	164	10	counting	count	VBG
cord-322516-wekvet6f	164	11	at	at	IN
cord-322516-wekvet6f	164	12	least	least	RBS
cord-322516-wekvet6f	164	13	100	100	CD
cord-322516-wekvet6f	164	14	cells	cell	NNS
cord-322516-wekvet6f	164	15	for	for	IN
cord-322516-wekvet6f	164	16	each	each	DT
cord-322516-wekvet6f	164	17	sample	sample	NN
cord-322516-wekvet6f	164	18	.	.	.
cord-322516-wekvet6f	165	1	The	the	DT
cord-322516-wekvet6f	165	2	experiment	experiment	NN
cord-322516-wekvet6f	165	3	was	be	VBD
cord-322516-wekvet6f	165	4	performed	perform	VBN
cord-322516-wekvet6f	165	5	five	five	CD
cord-322516-wekvet6f	165	6	times	time	NNS
cord-322516-wekvet6f	165	7	,	,	,
cord-322516-wekvet6f	165	8	with	with	IN
cord-322516-wekvet6f	165	9	one	one	CD
cord-322516-wekvet6f	165	10	representative	representative	JJ
cord-322516-wekvet6f	165	11	experiment	experiment	NN
cord-322516-wekvet6f	165	12	shown	show	VBN
cord-322516-wekvet6f	165	13	(	(	-LRB-
cord-322516-wekvet6f	165	14	Fig	Fig	NNP
cord-322516-wekvet6f	165	15	.	.	NNP
cord-322516-wekvet6f	165	16	7	7	CD
cord-322516-wekvet6f	165	17	)	)	-RRB-
cord-322516-wekvet6f	165	18	.	.	.
cord-322516-wekvet6f	166	1	Interestingly	interestingly	RB
cord-322516-wekvet6f	166	2	,	,	,
cord-322516-wekvet6f	166	3	when	when	WRB
cord-322516-wekvet6f	166	4	cells	cell	NNS
cord-322516-wekvet6f	166	5	were	be	VBD
cord-322516-wekvet6f	166	6	quantified	quantify	VBN
cord-322516-wekvet6f	166	7	in	in	IN
cord-322516-wekvet6f	166	8	this	this	DT
cord-322516-wekvet6f	166	9	way	way	NN
cord-322516-wekvet6f	166	10	,	,	,
cord-322516-wekvet6f	166	11	we	-PRON-	PRP
cord-322516-wekvet6f	166	12	observed	observe	VBD
cord-322516-wekvet6f	166	13	that	that	IN
cord-322516-wekvet6f	166	14	both	both	DT
cord-322516-wekvet6f	166	15	␤	␤	IN
cord-322516-wekvet6f	166	16	CA	CA	NNP
cord-322516-wekvet6f	166	17	and	and	CC
cord-322516-wekvet6f	166	18	FB1	FB1	NNP
cord-322516-wekvet6f	166	19	caused	cause	VBD
cord-322516-wekvet6f	166	20	a	a	DT
cord-322516-wekvet6f	166	21	slight	slight	JJ
cord-322516-wekvet6f	166	22	shift	shift	NN
cord-322516-wekvet6f	166	23	from	from	IN
cord-322516-wekvet6f	166	24	class	class	NN
cord-322516-wekvet6f	166	25	1	1	CD
cord-322516-wekvet6f	166	26	to	to	IN
cord-322516-wekvet6f	166	27	class	class	NN
cord-322516-wekvet6f	166	28	2	2	CD
cord-322516-wekvet6f	166	29	.	.	.
cord-322516-wekvet6f	167	1	The	the	DT
cord-322516-wekvet6f	167	2	significance	significance	NN
cord-322516-wekvet6f	167	3	of	of	IN
cord-322516-wekvet6f	167	4	this	this	DT
cord-322516-wekvet6f	167	5	observation	observation	NN
cord-322516-wekvet6f	167	6	is	be	VBZ
cord-322516-wekvet6f	167	7	not	not	RB
cord-322516-wekvet6f	167	8	clear	clear	JJ
cord-322516-wekvet6f	167	9	.	.	.
cord-322516-wekvet6f	168	1	PDMP	PDMP	NNP
cord-322516-wekvet6f	168	2	dramatically	dramatically	RB
cord-322516-wekvet6f	168	3	shifted	shift	VBD
cord-322516-wekvet6f	168	4	the	the	DT
cord-322516-wekvet6f	168	5	distribution	distribution	NN
cord-322516-wekvet6f	168	6	of	of	IN
cord-322516-wekvet6f	168	7	IBV	IBV	NNP
cord-322516-wekvet6f	168	8	M	M	NNP
cord-322516-wekvet6f	168	9	from	from	IN
cord-322516-wekvet6f	168	10	mainly	mainly	RB
cord-322516-wekvet6f	168	11	class	class	NN
cord-322516-wekvet6f	168	12	1	1	CD
cord-322516-wekvet6f	168	13	in	in	IN
cord-322516-wekvet6f	168	14	the	the	DT
cord-322516-wekvet6f	168	15	control	control	NN
cord-322516-wekvet6f	168	16	cells	cell	NNS
cord-322516-wekvet6f	168	17	to	to	IN
cord-322516-wekvet6f	168	18	mainly	mainly	RB
cord-322516-wekvet6f	168	19	class	class	NN
cord-322516-wekvet6f	168	20	3	3	CD
cord-322516-wekvet6f	168	21	.	.	.
cord-322516-wekvet6f	169	1	Pretreatment	pretreatment	JJ
cord-322516-wekvet6f	169	2	with	with	IN
cord-322516-wekvet6f	169	3	either	either	DT
cord-322516-wekvet6f	169	4	␤	␤	NNP
cord-322516-wekvet6f	169	5	CA	CA	NNP
cord-322516-wekvet6f	169	6	or	or	CC
cord-322516-wekvet6f	169	7	FB1	FB1	NNP
cord-322516-wekvet6f	169	8	significantly	significantly	RB
cord-322516-wekvet6f	169	9	reduced	reduce	VBD
cord-322516-wekvet6f	169	10	this	this	DT
cord-322516-wekvet6f	169	11	shift	shift	NN
cord-322516-wekvet6f	169	12	in	in	IN
cord-322516-wekvet6f	169	13	the	the	DT
cord-322516-wekvet6f	169	14	staining	staining	NN
cord-322516-wekvet6f	169	15	pattern	pattern	NN
cord-322516-wekvet6f	169	16	of	of	IN
cord-322516-wekvet6f	169	17	IBV	IBV	NNP
cord-322516-wekvet6f	169	18	M	M	NNP
cord-322516-wekvet6f	169	19	,	,	,
cord-322516-wekvet6f	169	20	suggesting	suggest	VBG
cord-322516-wekvet6f	169	21	that	that	IN
cord-322516-wekvet6f	169	22	accumula-	accumula-	JJ
cord-322516-wekvet6f	169	23	Figure	figure	NN
cord-322516-wekvet6f	169	24	5	5	CD
cord-322516-wekvet6f	169	25	.	.	.
cord-322516-wekvet6f	170	1	PDMP	PDMP	NNP
cord-322516-wekvet6f	170	2	induced	induce	VBD
cord-322516-wekvet6f	170	3	the	the	DT
cord-322516-wekvet6f	170	4	redistribution	redistribution	NN
cord-322516-wekvet6f	170	5	of	of	IN
cord-322516-wekvet6f	170	6	the	the	DT
cord-322516-wekvet6f	170	7	endogenous	endogenous	JJ
cord-322516-wekvet6f	170	8	IC	IC	NNP
cord-322516-wekvet6f	170	9	protein	protein	NN
cord-322516-wekvet6f	170	10	,	,	,
cord-322516-wekvet6f	170	11	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	170	12	,	,	,
cord-322516-wekvet6f	170	13	to	to	IN
cord-322516-wekvet6f	170	14	the	the	DT
cord-322516-wekvet6f	170	15	ER	ER	NNP
cord-322516-wekvet6f	170	16	.	.	.
cord-322516-wekvet6f	171	1	Vero	Vero	NNP
cord-322516-wekvet6f	171	2	cells	cell	NNS
cord-322516-wekvet6f	171	3	were	be	VBD
cord-322516-wekvet6f	171	4	incubated	incubate	VBN
cord-322516-wekvet6f	171	5	with	with	IN
cord-322516-wekvet6f	171	6	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	171	7	for	for	IN
cord-322516-wekvet6f	171	8	1	1	CD
cord-322516-wekvet6f	171	9	h	h	NN
cord-322516-wekvet6f	171	10	and	and	CC
cord-322516-wekvet6f	171	11	then	then	RB
cord-322516-wekvet6f	171	12	incubated	incubate	VBD
cord-322516-wekvet6f	171	13	for	for	IN
cord-322516-wekvet6f	171	14	1	1	CD
cord-322516-wekvet6f	171	15	h	h	NN
cord-322516-wekvet6f	171	16	in	in	IN
cord-322516-wekvet6f	171	17	the	the	DT
cord-322516-wekvet6f	171	18	presence	presence	NN
cord-322516-wekvet6f	171	19	either	either	CC
cord-322516-wekvet6f	171	20	1	1	CD
cord-322516-wekvet6f	171	21	%	%	NN
cord-322516-wekvet6f	171	22	isopropanol	isopropanol	NN
cord-322516-wekvet6f	171	23	(	(	-LRB-
cord-322516-wekvet6f	171	24	control	control	NN
cord-322516-wekvet6f	171	25	)	)	-RRB-
cord-322516-wekvet6f	171	26	or	or	CC
cord-322516-wekvet6f	171	27	100	100	CD
cord-322516-wekvet6f	171	28	M	M	NNP
cord-322516-wekvet6f	171	29	PDMP	PDMP	NNP
cord-322516-wekvet6f	171	30	.	.	.
cord-322516-wekvet6f	172	1	Cells	cell	NNS
cord-322516-wekvet6f	172	2	were	be	VBD
cord-322516-wekvet6f	172	3	then	then	RB
cord-322516-wekvet6f	172	4	fixed	fix	VBN
cord-322516-wekvet6f	172	5	and	and	CC
cord-322516-wekvet6f	172	6	prepared	prepare	VBN
cord-322516-wekvet6f	172	7	for	for	IN
cord-322516-wekvet6f	172	8	indirect	indirect	JJ
cord-322516-wekvet6f	172	9	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	172	10	with	with	IN
cord-322516-wekvet6f	172	11	antibodies	antibody	NNS
cord-322516-wekvet6f	172	12	to	to	IN
cord-322516-wekvet6f	172	13	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	172	14	.	.	.
cord-322516-wekvet6f	173	1	For	for	IN
cord-322516-wekvet6f	173	2	each	each	DT
cord-322516-wekvet6f	173	3	experimental	experimental	JJ
cord-322516-wekvet6f	173	4	group	group	NN
cord-322516-wekvet6f	173	5	,	,	,
cord-322516-wekvet6f	173	6	the	the	DT
cord-322516-wekvet6f	173	7	Nomarski	Nomarski	NNP
cord-322516-wekvet6f	173	8	image	image	NN
cord-322516-wekvet6f	173	9	is	be	VBZ
cord-322516-wekvet6f	173	10	shown	show	VBN
cord-322516-wekvet6f	173	11	on	on	IN
cord-322516-wekvet6f	173	12	the	the	DT
cord-322516-wekvet6f	173	13	left	left	NN
cord-322516-wekvet6f	173	14	and	and	CC
cord-322516-wekvet6f	173	15	the	the	DT
cord-322516-wekvet6f	173	16	fluorescence	fluorescence	NN
cord-322516-wekvet6f	173	17	image	image	NN
cord-322516-wekvet6f	173	18	on	on	IN
cord-322516-wekvet6f	173	19	the	the	DT
cord-322516-wekvet6f	173	20	right	right	NN
cord-322516-wekvet6f	173	21	.	.	.
cord-322516-wekvet6f	174	1	Bar	bar	NN
cord-322516-wekvet6f	174	2	,	,	,
cord-322516-wekvet6f	174	3	10	10	CD
cord-322516-wekvet6f	174	4	m.	m.	NN
cord-322516-wekvet6f	174	5	 	 	_SP
cord-322516-wekvet6f	175	1	The	the	DT
cord-322516-wekvet6f	175	2	pretreatment	pretreatment	NN
cord-322516-wekvet6f	175	3	experiments	experiment	NNS
cord-322516-wekvet6f	175	4	suggested	suggest	VBD
cord-322516-wekvet6f	175	5	that	that	IN
cord-322516-wekvet6f	175	6	increased	increase	VBN
cord-322516-wekvet6f	175	7	levels	level	NNS
cord-322516-wekvet6f	175	8	of	of	IN
cord-322516-wekvet6f	175	9	ceramide	ceramide	NN
cord-322516-wekvet6f	175	10	mediate	mediate	VBP
cord-322516-wekvet6f	175	11	the	the	DT
cord-322516-wekvet6f	175	12	PDMP	PDMP	NNP
cord-322516-wekvet6f	175	13	-	-	HYPH
cord-322516-wekvet6f	175	14	induced	induce	VBN
cord-322516-wekvet6f	175	15	effects	effect	NNS
cord-322516-wekvet6f	175	16	on	on	IN
cord-322516-wekvet6f	175	17	IBV	IBV	NNP
cord-322516-wekvet6f	175	18	M	M	NNP
cord-322516-wekvet6f	175	19	localization	localization	NN
cord-322516-wekvet6f	175	20	.	.	.
cord-322516-wekvet6f	176	1	Ceramide	ceramide	NN
cord-322516-wekvet6f	176	2	can	can	MD
cord-322516-wekvet6f	176	3	act	act	VB
cord-322516-wekvet6f	176	4	as	as	IN
cord-322516-wekvet6f	176	5	a	a	DT
cord-322516-wekvet6f	176	6	second	second	JJ
cord-322516-wekvet6f	176	7	messenger	messenger	NN
cord-322516-wekvet6f	176	8	(	(	-LRB-
cord-322516-wekvet6f	176	9	for	for	IN
cord-322516-wekvet6f	176	10	review	review	NN
cord-322516-wekvet6f	176	11	see	see	VB
cord-322516-wekvet6f	176	12	Hannun	Hannun	NNP
cord-322516-wekvet6f	176	13	,	,	,
cord-322516-wekvet6f	176	14	1994	1994	CD
cord-322516-wekvet6f	176	15	)	)	-RRB-
cord-322516-wekvet6f	176	16	and	and	CC
cord-322516-wekvet6f	176	17	has	have	VBZ
cord-322516-wekvet6f	176	18	been	be	VBN
cord-322516-wekvet6f	176	19	suggested	suggest	VBN
cord-322516-wekvet6f	176	20	to	to	TO
cord-322516-wekvet6f	176	21	be	be	VB
cord-322516-wekvet6f	176	22	the	the	DT
cord-322516-wekvet6f	176	23	mediator	mediator	NN
cord-322516-wekvet6f	176	24	of	of	IN
cord-322516-wekvet6f	176	25	some	some	DT
cord-322516-wekvet6f	176	26	of	of	IN
cord-322516-wekvet6f	176	27	the	the	DT
cord-322516-wekvet6f	176	28	effects	effect	NNS
cord-322516-wekvet6f	176	29	of	of	IN
cord-322516-wekvet6f	176	30	PDMP	PDMP	NNP
cord-322516-wekvet6f	176	31	in	in	IN
cord-322516-wekvet6f	176	32	CHO	CHO	NNP
cord-322516-wekvet6f	176	33	cells	cell	NNS
cord-322516-wekvet6f	176	34	(	(	-LRB-
cord-322516-wekvet6f	176	35	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	176	36	and	and	CC
cord-322516-wekvet6f	176	37	Pagano	Pagano	NNP
cord-322516-wekvet6f	176	38	,	,	,
cord-322516-wekvet6f	176	39	1993	1993	CD
cord-322516-wekvet6f	176	40	)	)	-RRB-
cord-322516-wekvet6f	176	41	.	.	.
cord-322516-wekvet6f	177	1	Furthermore	furthermore	RB
cord-322516-wekvet6f	177	2	,	,	,
cord-322516-wekvet6f	177	3	in	in	IN
cord-322516-wekvet6f	177	4	several	several	JJ
cord-322516-wekvet6f	177	5	systems	system	NNS
cord-322516-wekvet6f	177	6	,	,	,
cord-322516-wekvet6f	177	7	cellular	cellular	JJ
cord-322516-wekvet6f	177	8	levels	level	NNS
cord-322516-wekvet6f	177	9	of	of	IN
cord-322516-wekvet6f	177	10	ceramide	ceramide	NN
cord-322516-wekvet6f	177	11	increased	increase	VBD
cord-322516-wekvet6f	177	12	upon	upon	IN
cord-322516-wekvet6f	177	13	treatment	treatment	NN
cord-322516-wekvet6f	177	14	with	with	IN
cord-322516-wekvet6f	177	15	PDMP	PDMP	NNP
cord-322516-wekvet6f	177	16	or	or	CC
cord-322516-wekvet6f	177	17	one	one	CD
cord-322516-wekvet6f	177	18	of	of	IN
cord-322516-wekvet6f	177	19	its	-PRON-	PRP$
cord-322516-wekvet6f	177	20	more	more	RBR
cord-322516-wekvet6f	177	21	soluble	soluble	JJ
cord-322516-wekvet6f	177	22	analogues	analogue	NNS
cord-322516-wekvet6f	177	23	(	(	-LRB-
cord-322516-wekvet6f	177	24	for	for	IN
cord-322516-wekvet6f	177	25	example	example	NN
cord-322516-wekvet6f	177	26	see	see	VBP
cord-322516-wekvet6f	177	27	Rani	Rani	NNP
cord-322516-wekvet6f	177	28	et	et	NNP
cord-322516-wekvet6f	177	29	al	al	NNP
cord-322516-wekvet6f	177	30	.	.	NNP
cord-322516-wekvet6f	177	31	,	,	,
cord-322516-wekvet6f	177	32	1995	1995	CD
cord-322516-wekvet6f	177	33	;	;	:
cord-322516-wekvet6f	177	34	Posse	Posse	NNP
cord-322516-wekvet6f	177	35	de	de	FW
cord-322516-wekvet6f	177	36	Chaves	Chaves	NNP
cord-322516-wekvet6f	177	37	et	et	NNP
cord-322516-wekvet6f	177	38	al	al	NNP
cord-322516-wekvet6f	177	39	.	.	NNP
cord-322516-wekvet6f	177	40	,	,	,
cord-322516-wekvet6f	177	41	1997	1997	CD
cord-322516-wekvet6f	177	42	)	)	-RRB-
cord-322516-wekvet6f	177	43	.	.	.
cord-322516-wekvet6f	178	1	We	-PRON-	PRP
cord-322516-wekvet6f	178	2	measured	measure	VBD
cord-322516-wekvet6f	178	3	the	the	DT
cord-322516-wekvet6f	178	4	levels	level	NNS
cord-322516-wekvet6f	178	5	of	of	IN
cord-322516-wekvet6f	178	6	ceramide	ceramide	NN
cord-322516-wekvet6f	178	7	after	after	IN
cord-322516-wekvet6f	178	8	various	various	JJ
cord-322516-wekvet6f	178	9	treatments	treatment	NNS
cord-322516-wekvet6f	178	10	by	by	IN
cord-322516-wekvet6f	178	11	pulse	pulse	NN
cord-322516-wekvet6f	178	12	-	-	HYPH
cord-322516-wekvet6f	178	13	labeling	labeling	NN
cord-322516-wekvet6f	178	14	with	with	IN
cord-322516-wekvet6f	178	15	[	[	-LRB-
cord-322516-wekvet6f	178	16	3	3	CD
cord-322516-wekvet6f	178	17	H]palmitate	H]palmitate	NNP
cord-322516-wekvet6f	178	18	.	.	.
cord-322516-wekvet6f	179	1	After	after	IN
cord-322516-wekvet6f	179	2	labeling	labeling	NN
cord-322516-wekvet6f	179	3	and	and	CC
cord-322516-wekvet6f	179	4	treatment	treatment	NN
cord-322516-wekvet6f	179	5	,	,	,
cord-322516-wekvet6f	179	6	cellular	cellular	JJ
cord-322516-wekvet6f	179	7	lipids	lipid	NNS
cord-322516-wekvet6f	179	8	were	be	VBD
cord-322516-wekvet6f	179	9	extracted	extract	VBN
cord-322516-wekvet6f	179	10	and	and	CC
cord-322516-wekvet6f	179	11	run	run	VBN
cord-322516-wekvet6f	179	12	on	on	IN
cord-322516-wekvet6f	179	13	chromatography	chromatography	NN
cord-322516-wekvet6f	179	14	plates	plate	NNS
cord-322516-wekvet6f	179	15	.	.	.
cord-322516-wekvet6f	180	1	The	the	DT
cord-322516-wekvet6f	180	2	appropriate	appropriate	JJ
cord-322516-wekvet6f	180	3	spots	spot	NNS
cord-322516-wekvet6f	180	4	corresponding	correspond	VBG
cord-322516-wekvet6f	180	5	to	to	IN
cord-322516-wekvet6f	180	6	ceramide	ceramide	NN
cord-322516-wekvet6f	180	7	were	be	VBD
cord-322516-wekvet6f	180	8	scraped	scrape	VBN
cord-322516-wekvet6f	180	9	and	and	CC
cord-322516-wekvet6f	180	10	counted	count	VBN
cord-322516-wekvet6f	180	11	.	.	.
cord-322516-wekvet6f	181	1	Consistent	consistent	JJ
cord-322516-wekvet6f	181	2	with	with	IN
cord-322516-wekvet6f	181	3	our	-PRON-	PRP$
cord-322516-wekvet6f	181	4	hypothesis	hypothesis	NN
cord-322516-wekvet6f	181	5	,	,	,
cord-322516-wekvet6f	181	6	Fig	Fig	NNP
cord-322516-wekvet6f	181	7	.	.	.
cord-322516-wekvet6f	181	8	8	8	CD
cord-322516-wekvet6f	182	1	A	a	DT
cord-322516-wekvet6f	182	2	shows	show	NNS
cord-322516-wekvet6f	182	3	that	that	IN
cord-322516-wekvet6f	182	4	PDMP	PDMP	NNP
cord-322516-wekvet6f	182	5	treatment	treatment	NN
cord-322516-wekvet6f	182	6	increased	increase	VBD
cord-322516-wekvet6f	182	7	the	the	DT
cord-322516-wekvet6f	182	8	levels	level	NNS
cord-322516-wekvet6f	182	9	of	of	IN
cord-322516-wekvet6f	182	10	ceramide	ceramide	NN
cord-322516-wekvet6f	182	11	2.5-fold	2.5-fold	CD
cord-322516-wekvet6f	182	12	over	over	IN
cord-322516-wekvet6f	182	13	control	control	NN
cord-322516-wekvet6f	182	14	levels	level	NNS
cord-322516-wekvet6f	182	15	.	.	.
cord-322516-wekvet6f	183	1	Pretreatment	pretreatment	JJ
cord-322516-wekvet6f	183	2	with	with	IN
cord-322516-wekvet6f	183	3	␤	␤	.
cord-322516-wekvet6f	184	1	CA	CA	NNP
cord-322516-wekvet6f	184	2	reduced	reduce	VBD
cord-322516-wekvet6f	184	3	PDMPinduced	pdmpinduced	JJ
cord-322516-wekvet6f	184	4	ceramide	ceramide	NN
cord-322516-wekvet6f	184	5	accumulation	accumulation	NN
cord-322516-wekvet6f	184	6	to	to	IN
cord-322516-wekvet6f	184	7	roughly	roughly	RB
cord-322516-wekvet6f	184	8	half	half	NN
cord-322516-wekvet6f	184	9	of	of	IN
cord-322516-wekvet6f	184	10	control	control	NN
cord-322516-wekvet6f	184	11	levels	level	NNS
cord-322516-wekvet6f	184	12	,	,	,
cord-322516-wekvet6f	184	13	but	but	CC
cord-322516-wekvet6f	184	14	this	this	DT
cord-322516-wekvet6f	184	15	level	level	NN
cord-322516-wekvet6f	184	16	was	be	VBD
cord-322516-wekvet6f	184	17	still	still	RB
cord-322516-wekvet6f	184	18	threefold	threefold	RB
cord-322516-wekvet6f	184	19	higher	high	JJR
cord-322516-wekvet6f	184	20	than	than	IN
cord-322516-wekvet6f	184	21	cells	cell	NNS
cord-322516-wekvet6f	184	22	treated	treat	VBN
cord-322516-wekvet6f	184	23	with	with	IN
cord-322516-wekvet6f	184	24	␤	␤	NNP
cord-322516-wekvet6f	184	25	CA	CA	NNP
cord-322516-wekvet6f	184	26	alone	alone	RB
cord-322516-wekvet6f	184	27	.	.	.
cord-322516-wekvet6f	185	1	Fig	Fig	NNP
cord-322516-wekvet6f	185	2	.	.	.
cord-322516-wekvet6f	186	1	8	8	CD
cord-322516-wekvet6f	186	2	B	b	NN
cord-322516-wekvet6f	186	3	is	be	VBZ
cord-322516-wekvet6f	186	4	a	a	DT
cord-322516-wekvet6f	186	5	representative	representative	JJ
cord-322516-wekvet6f	186	6	fluorograph	fluorograph	NN
cord-322516-wekvet6f	186	7	showing	show	VBG
cord-322516-wekvet6f	186	8	the	the	DT
cord-322516-wekvet6f	186	9	ceramide	ceramide	NN
cord-322516-wekvet6f	186	10	region	region	NN
cord-322516-wekvet6f	186	11	that	that	WDT
cord-322516-wekvet6f	186	12	was	be	VBD
cord-322516-wekvet6f	186	13	quantified	quantify	VBN
cord-322516-wekvet6f	186	14	in	in	IN
cord-322516-wekvet6f	186	15	Fig	Fig	NNP
cord-322516-wekvet6f	186	16	.	.	.
cord-322516-wekvet6f	187	1	8	8	CD
cord-322516-wekvet6f	187	2	A.	a.	NN
cord-322516-wekvet6f	188	1	Interestingly	interestingly	RB
cord-322516-wekvet6f	188	2	,	,	,
cord-322516-wekvet6f	188	3	we	-PRON-	PRP
cord-322516-wekvet6f	188	4	noticed	notice	VBD
cord-322516-wekvet6f	188	5	the	the	DT
cord-322516-wekvet6f	188	6	appearance	appearance	NN
cord-322516-wekvet6f	188	7	of	of	IN
cord-322516-wekvet6f	188	8	a	a	DT
cord-322516-wekvet6f	188	9	lower	lower	RBR
cord-322516-wekvet6f	188	10	migrating	migrate	VBG
cord-322516-wekvet6f	188	11	ceramide	ceramide	NN
cord-322516-wekvet6f	188	12	band	band	NN
cord-322516-wekvet6f	188	13	in	in	IN
cord-322516-wekvet6f	188	14	PDMP	PDMP	NNP
cord-322516-wekvet6f	188	15	-	-	HYPH
cord-322516-wekvet6f	188	16	treated	treat	VBN
cord-322516-wekvet6f	188	17	cells	cell	NNS
cord-322516-wekvet6f	188	18	.	.	.
cord-322516-wekvet6f	189	1	The	the	DT
cord-322516-wekvet6f	189	2	pretreatment	pretreatment	NN
cord-322516-wekvet6f	189	3	experiments	experiment	NNS
cord-322516-wekvet6f	189	4	as	as	RB
cord-322516-wekvet6f	189	5	well	well	RB
cord-322516-wekvet6f	189	6	as	as	IN
cord-322516-wekvet6f	189	7	lipid	lipid	NN
cord-322516-wekvet6f	189	8	analysis	analysis	NN
cord-322516-wekvet6f	189	9	implicated	implicate	VBN
cord-322516-wekvet6f	189	10	ceramide	ceramide	NN
cord-322516-wekvet6f	189	11	as	as	IN
cord-322516-wekvet6f	189	12	the	the	DT
cord-322516-wekvet6f	189	13	mediator	mediator	NN
cord-322516-wekvet6f	189	14	of	of	IN
cord-322516-wekvet6f	189	15	PDMP	PDMP	NNP
cord-322516-wekvet6f	189	16	effects	effect	NNS
cord-322516-wekvet6f	189	17	.	.	.
cord-322516-wekvet6f	190	1	If	if	IN
cord-322516-wekvet6f	190	2	this	this	DT
cord-322516-wekvet6f	190	3	were	be	VBD
cord-322516-wekvet6f	190	4	true	true	JJ
cord-322516-wekvet6f	190	5	,	,	,
cord-322516-wekvet6f	190	6	addition	addition	NN
cord-322516-wekvet6f	190	7	of	of	IN
cord-322516-wekvet6f	190	8	a	a	DT
cord-322516-wekvet6f	190	9	soluble	soluble	JJ
cord-322516-wekvet6f	190	10	,	,	,
cord-322516-wekvet6f	190	11	short	short	JJ
cord-322516-wekvet6f	190	12	-	-	HYPH
cord-322516-wekvet6f	190	13	chain	chain	NN
cord-322516-wekvet6f	190	14	analogue	analogue	NN
cord-322516-wekvet6f	190	15	of	of	IN
cord-322516-wekvet6f	190	16	ceramide	ceramide	NN
cord-322516-wekvet6f	190	17	might	may	MD
cord-322516-wekvet6f	190	18	mimic	mimic	VB
cord-322516-wekvet6f	190	19	the	the	DT
cord-322516-wekvet6f	190	20	effects	effect	NNS
cord-322516-wekvet6f	190	21	of	of	IN
cord-322516-wekvet6f	190	22	PDMP	PDMP	NNP
cord-322516-wekvet6f	190	23	.	.	.
cord-322516-wekvet6f	191	1	Indeed	indeed	RB
cord-322516-wekvet6f	191	2	,	,	,
cord-322516-wekvet6f	191	3	one	one	CD
cord-322516-wekvet6f	191	4	such	such	JJ
cord-322516-wekvet6f	191	5	cell	cell	NN
cord-322516-wekvet6f	191	6	-	-	HYPH
cord-322516-wekvet6f	191	7	permeable	permeable	JJ
cord-322516-wekvet6f	191	8	analogue	analogue	NN
cord-322516-wekvet6f	191	9	of	of	IN
cord-322516-wekvet6f	191	10	ceramide	ceramide	NN
cord-322516-wekvet6f	191	11	,	,	,
cord-322516-wekvet6f	191	12	N	n	CD
cord-322516-wekvet6f	191	13	-hexanoylsphingosine	-hexanoylsphingosine	NN
cord-322516-wekvet6f	191	14	(	(	-LRB-
cord-322516-wekvet6f	191	15	C	C	NNP
cord-322516-wekvet6f	191	16	6	6	CD
cord-322516-wekvet6f	191	17	Cer	Cer	NNP
cord-322516-wekvet6f	191	18	)	)	-RRB-
cord-322516-wekvet6f	191	19	,	,	,
cord-322516-wekvet6f	191	20	reproduces	reproduce	VBZ
cord-322516-wekvet6f	191	21	the	the	DT
cord-322516-wekvet6f	191	22	effects	effect	NNS
cord-322516-wekvet6f	191	23	of	of	IN
cord-322516-wekvet6f	191	24	PDMP	PDMP	NNP
cord-322516-wekvet6f	191	25	on	on	IN
cord-322516-wekvet6f	191	26	anterograde	anterograde	JJ
cord-322516-wekvet6f	191	27	traffic	traffic	NN
cord-322516-wekvet6f	191	28	of	of	IN
cord-322516-wekvet6f	191	29	VSV	VSV	NNP
cord-322516-wekvet6f	191	30	G	G	NNP
cord-322516-wekvet6f	191	31	in	in	IN
cord-322516-wekvet6f	191	32	CHO	CHO	NNP
cord-322516-wekvet6f	191	33	cells	cell	NNS
cord-322516-wekvet6f	191	34	(	(	-LRB-
cord-322516-wekvet6f	191	35	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	191	36	and	and	CC
cord-322516-wekvet6f	191	37	Pagano	Pagano	NNP
cord-322516-wekvet6f	191	38	,	,	,
cord-322516-wekvet6f	191	39	1993	1993	CD
cord-322516-wekvet6f	191	40	)	)	-RRB-
cord-322516-wekvet6f	191	41	.	.	.
cord-322516-wekvet6f	192	1	We	-PRON-	PRP
cord-322516-wekvet6f	192	2	first	first	RB
cord-322516-wekvet6f	192	3	asked	ask	VBD
cord-322516-wekvet6f	192	4	whether	whether	IN
cord-322516-wekvet6f	192	5	C	C	NNP
cord-322516-wekvet6f	192	6	6	6	CD
cord-322516-wekvet6f	192	7	Cer	Cer	NNP
cord-322516-wekvet6f	192	8	slowed	slow	VBD
cord-322516-wekvet6f	192	9	anterograde	anterograde	JJ
cord-322516-wekvet6f	192	10	traffic	traffic	NN
cord-322516-wekvet6f	192	11	in	in	IN
cord-322516-wekvet6f	192	12	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	192	13	cells	cell	NNS
cord-322516-wekvet6f	192	14	.	.	.
cord-322516-wekvet6f	193	1	A	a	DT
cord-322516-wekvet6f	193	2	pulse	pulse	NN
cord-322516-wekvet6f	193	3	-	-	HYPH
cord-322516-wekvet6f	193	4	chase	chase	NN
cord-322516-wekvet6f	193	5	labeling	labeling	NN
cord-322516-wekvet6f	193	6	experiment	experiment	NN
cord-322516-wekvet6f	193	7	with	with	IN
cord-322516-wekvet6f	193	8	VSV	VSV	NNP
cord-322516-wekvet6f	193	9	-	-	HYPH
cord-322516-wekvet6f	193	10	infected	infect	VBN
cord-322516-wekvet6f	193	11	cells	cell	NNS
cord-322516-wekvet6f	193	12	was	be	VBD
cord-322516-wekvet6f	193	13	performed	perform	VBN
cord-322516-wekvet6f	193	14	,	,	,
cord-322516-wekvet6f	193	15	with	with	IN
cord-322516-wekvet6f	193	16	cells	cell	NNS
cord-322516-wekvet6f	193	17	chased	chase	VBN
cord-322516-wekvet6f	193	18	in	in	IN
cord-322516-wekvet6f	193	19	the	the	DT
cord-322516-wekvet6f	193	20	absence	absence	NN
cord-322516-wekvet6f	193	21	or	or	CC
cord-322516-wekvet6f	193	22	presence	presence	NN
cord-322516-wekvet6f	193	23	of	of	IN
cord-322516-wekvet6f	193	24	25	25	CD
cord-322516-wekvet6f	193	25	M	M	NNP
cord-322516-wekvet6f	193	26	C	C	NNP
cord-322516-wekvet6f	193	27	6	6	CD
cord-322516-wekvet6f	193	28	Cer	cer	NN
cord-322516-wekvet6f	193	29	.	.	.
cord-322516-wekvet6f	194	1	C	C	NNP
cord-322516-wekvet6f	194	2	6	6	CD
cord-322516-wekvet6f	194	3	Cer	Cer	NNP
cord-322516-wekvet6f	194	4	slowed	slow	VBD
cord-322516-wekvet6f	194	5	the	the	DT
cord-322516-wekvet6f	194	6	rate	rate	NN
cord-322516-wekvet6f	194	7	of	of	IN
cord-322516-wekvet6f	194	8	anterograde	anterograde	JJ
cord-322516-wekvet6f	194	9	traffic	traffic	NN
cord-322516-wekvet6f	194	10	in	in	IN
cord-322516-wekvet6f	194	11	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	194	12	cells	cell	NNS
cord-322516-wekvet6f	195	1	‫-5.2ف‬fold	‫-5.2ف‬fold	NNP
cord-322516-wekvet6f	195	2	(	(	-LRB-
cord-322516-wekvet6f	195	3	data	datum	NNS
cord-322516-wekvet6f	195	4	not	not	RB
cord-322516-wekvet6f	195	5	shown	show	VBN
cord-322516-wekvet6f	195	6	)	)	-RRB-
cord-322516-wekvet6f	195	7	.	.	.
cord-322516-wekvet6f	196	1	We	-PRON-	PRP
cord-322516-wekvet6f	196	2	went	go	VBD
cord-322516-wekvet6f	196	3	on	on	RP
cord-322516-wekvet6f	196	4	to	to	TO
cord-322516-wekvet6f	196	5	use	use	VB
cord-322516-wekvet6f	196	6	C	C	NNP
cord-322516-wekvet6f	196	7	6	6	CD
cord-322516-wekvet6f	196	8	Cer	cer	NN
cord-322516-wekvet6f	196	9	in	in	IN
cord-322516-wekvet6f	196	10	our	-PRON-	PRP$
cord-322516-wekvet6f	196	11	indirect	indirect	JJ
cord-322516-wekvet6f	196	12	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	196	13	assay	assay	NN
cord-322516-wekvet6f	196	14	.	.	.
cord-322516-wekvet6f	197	1	As	as	IN
cord-322516-wekvet6f	197	2	expected	expect	VBN
cord-322516-wekvet6f	197	3	,	,	,
cord-322516-wekvet6f	197	4	C	C	NNP
cord-322516-wekvet6f	197	5	6	6	CD
cord-322516-wekvet6f	197	6	Cer	Cer	NNP
cord-322516-wekvet6f	197	7	had	have	VBD
cord-322516-wekvet6f	197	8	no	no	DT
cord-322516-wekvet6f	197	9	effect	effect	NN
cord-322516-wekvet6f	197	10	on	on	IN
cord-322516-wekvet6f	197	11	the	the	DT
cord-322516-wekvet6f	197	12	localization	localization	NN
cord-322516-wekvet6f	197	13	of	of	IN
cord-322516-wekvet6f	197	14	either	either	DT
cord-322516-wekvet6f	197	15	Man	Man	NNP
cord-322516-wekvet6f	197	16	II	II	NNP
cord-322516-wekvet6f	197	17	or	or	CC
cord-322516-wekvet6f	197	18	␤	␤	.
cord-322516-wekvet6f	197	19	-COP	-cop	ADD
cord-322516-wekvet6f	198	1	(	(	-LRB-
cord-322516-wekvet6f	198	2	Fig	Fig	NNP
cord-322516-wekvet6f	198	3	.	.	.
cord-322516-wekvet6f	198	4	9	9	CD
cord-322516-wekvet6f	198	5	)	)	-RRB-
cord-322516-wekvet6f	198	6	.	.	.
cord-322516-wekvet6f	199	1	However	however	RB
cord-322516-wekvet6f	199	2	,	,	,
cord-322516-wekvet6f	199	3	contrary	contrary	JJ
cord-322516-wekvet6f	199	4	to	to	IN
cord-322516-wekvet6f	199	5	our	-PRON-	PRP$
cord-322516-wekvet6f	199	6	expectation	expectation	NN
cord-322516-wekvet6f	199	7	,	,	,
cord-322516-wekvet6f	199	8	C	C	NNP
cord-322516-wekvet6f	199	9	6	6	CD
cord-322516-wekvet6f	199	10	Cer	Cer	NNP
cord-322516-wekvet6f	199	11	did	do	VBD
cord-322516-wekvet6f	199	12	not	not	RB
cord-322516-wekvet6f	199	13	alter	alter	VB
cord-322516-wekvet6f	199	14	the	the	DT
cord-322516-wekvet6f	199	15	localization	localization	NN
cord-322516-wekvet6f	199	16	of	of	IN
cord-322516-wekvet6f	199	17	either	either	CC
cord-322516-wekvet6f	199	18	IBV	IBV	NNP
cord-322516-wekvet6f	199	19	M	M	NNP
cord-322516-wekvet6f	199	20	or	or	CC
cord-322516-wekvet6f	199	21	ER	ER	NNP
cord-322516-wekvet6f	199	22	-	-	HYPH
cord-322516-wekvet6f	199	23	GIC-53	GIC-53	NNP
cord-322516-wekvet6f	199	24	.	.	.
cord-322516-wekvet6f	200	1	This	this	DT
cord-322516-wekvet6f	200	2	suggests	suggest	VBZ
cord-322516-wekvet6f	200	3	that	that	IN
cord-322516-wekvet6f	200	4	exogenously	exogenously	RB
cord-322516-wekvet6f	200	5	added	add	VBN
cord-322516-wekvet6f	200	6	C	C	NNP
cord-322516-wekvet6f	200	7	6	6	CD
cord-322516-wekvet6f	200	8	Cer	cer	NN
cord-322516-wekvet6f	200	9	and	and	CC
cord-322516-wekvet6f	200	10	ceramide	ceramide	NN
cord-322516-wekvet6f	200	11	generated	generate	VBN
cord-322516-wekvet6f	200	12	by	by	IN
cord-322516-wekvet6f	200	13	treatment	treatment	NN
cord-322516-wekvet6f	200	14	with	with	IN
cord-322516-wekvet6f	200	15	PDMP	PDMP	NNP
cord-322516-wekvet6f	200	16	do	do	VBP
cord-322516-wekvet6f	200	17	not	not	RB
cord-322516-wekvet6f	200	18	have	have	VB
cord-322516-wekvet6f	200	19	the	the	DT
cord-322516-wekvet6f	200	20	same	same	JJ
cord-322516-wekvet6f	200	21	effects	effect	NNS
cord-322516-wekvet6f	200	22	.	.	.
cord-322516-wekvet6f	201	1	Two	two	CD
cord-322516-wekvet6f	201	2	other	other	JJ
cord-322516-wekvet6f	201	3	soluble	soluble	JJ
cord-322516-wekvet6f	201	4	analogues	analogue	NNS
cord-322516-wekvet6f	201	5	of	of	IN
cord-322516-wekvet6f	201	6	ceramide	ceramide	NN
cord-322516-wekvet6f	201	7	,	,	,
cord-322516-wekvet6f	201	8	C	C	NNP
cord-322516-wekvet6f	201	9	2	2	CD
cord-322516-wekvet6f	201	10	Cer	Cer	NNP
cord-322516-wekvet6f	201	11	and	and	CC
cord-322516-wekvet6f	201	12	C	C	NNP
cord-322516-wekvet6f	201	13	8	8	CD
cord-322516-wekvet6f	201	14	Cer	Cer	NNP
cord-322516-wekvet6f	201	15	,	,	,
cord-322516-wekvet6f	201	16	were	be	VBD
cord-322516-wekvet6f	201	17	also	also	RB
cord-322516-wekvet6f	201	18	tested	test	VBN
cord-322516-wekvet6f	201	19	and	and	CC
cord-322516-wekvet6f	201	20	found	find	VBN
cord-322516-wekvet6f	201	21	to	to	TO
cord-322516-wekvet6f	201	22	have	have	VB
cord-322516-wekvet6f	201	23	no	no	DT
cord-322516-wekvet6f	201	24	effect	effect	NN
cord-322516-wekvet6f	201	25	on	on	IN
cord-322516-wekvet6f	201	26	the	the	DT
cord-322516-wekvet6f	201	27	localization	localization	NN
cord-322516-wekvet6f	201	28	of	of	IN
cord-322516-wekvet6f	201	29	IBV	IBV	NNP
cord-322516-wekvet6f	201	30	M	M	NNP
cord-322516-wekvet6f	201	31	(	(	-LRB-
cord-322516-wekvet6f	201	32	data	datum	NNS
cord-322516-wekvet6f	201	33	not	not	RB
cord-322516-wekvet6f	201	34	shown	show	VBN
cord-322516-wekvet6f	201	35	)	)	-RRB-
cord-322516-wekvet6f	201	36	.	.	.
cord-322516-wekvet6f	202	1	There	there	EX
cord-322516-wekvet6f	202	2	are	be	VBP
cord-322516-wekvet6f	202	3	two	two	CD
cord-322516-wekvet6f	202	4	possible	possible	JJ
cord-322516-wekvet6f	202	5	mechanisms	mechanism	NNS
cord-322516-wekvet6f	202	6	to	to	TO
cord-322516-wekvet6f	202	7	maintain	maintain	VB
cord-322516-wekvet6f	202	8	the	the	DT
cord-322516-wekvet6f	202	9	steady	steady	JJ
cord-322516-wekvet6f	202	10	-	-	HYPH
cord-322516-wekvet6f	202	11	state	state	NN
cord-322516-wekvet6f	202	12	localization	localization	NN
cord-322516-wekvet6f	202	13	of	of	IN
cord-322516-wekvet6f	202	14	proteins	protein	NNS
cord-322516-wekvet6f	202	15	to	to	IN
cord-322516-wekvet6f	202	16	specific	specific	JJ
cord-322516-wekvet6f	202	17	sites	site	NNS
cord-322516-wekvet6f	202	18	along	along	IN
cord-322516-wekvet6f	202	19	the	the	DT
cord-322516-wekvet6f	202	20	secretory	secretory	JJ
cord-322516-wekvet6f	202	21	pathway	pathway	NN
cord-322516-wekvet6f	202	22	:	:	:
cord-322516-wekvet6f	202	23	(	(	-LRB-
cord-322516-wekvet6f	202	24	a	a	LS
cord-322516-wekvet6f	202	25	)	)	-RRB-
cord-322516-wekvet6f	202	26	retention	retention	NN
cord-322516-wekvet6f	202	27	in	in	IN
cord-322516-wekvet6f	202	28	the	the	DT
cord-322516-wekvet6f	202	29	particular	particular	JJ
cord-322516-wekvet6f	202	30	compartment	compartment	NN
cord-322516-wekvet6f	202	31	,	,	,
cord-322516-wekvet6f	202	32	and	and	CC
cord-322516-wekvet6f	202	33	(	(	-LRB-
cord-322516-wekvet6f	202	34	b	b	NN
cord-322516-wekvet6f	202	35	)	)	-RRB-
cord-322516-wekvet6f	202	36	retrieval	retrieval	NN
cord-322516-wekvet6f	202	37	from	from	IN
cord-322516-wekvet6f	202	38	other	other	JJ
cord-322516-wekvet6f	202	39	compartments	compartment	NNS
cord-322516-wekvet6f	202	40	(	(	-LRB-
cord-322516-wekvet6f	202	41	Machamer	Machamer	NNP
cord-322516-wekvet6f	202	42	,	,	,
cord-322516-wekvet6f	202	43	1993	1993	CD
cord-322516-wekvet6f	202	44	;	;	:
cord-322516-wekvet6f	203	1	Nilsson	Nilsson	NNP
cord-322516-wekvet6f	203	2	and	and	CC
cord-322516-wekvet6f	203	3	Warren	Warren	NNP
cord-322516-wekvet6f	203	4	,	,	,
cord-322516-wekvet6f	203	5	1994	1994	CD
cord-322516-wekvet6f	203	6	)	)	-RRB-
cord-322516-wekvet6f	203	7	.	.	.
cord-322516-wekvet6f	204	1	The	the	DT
cord-322516-wekvet6f	204	2	redistribution	redistribution	NN
cord-322516-wekvet6f	204	3	of	of	IN
cord-322516-wekvet6f	204	4	IBV	IBV	NNP
cord-322516-wekvet6f	204	5	M	M	NNP
cord-322516-wekvet6f	204	6	induced	induce	VBN
cord-322516-wekvet6f	204	7	by	by	IN
cord-322516-wekvet6f	204	8	PDMP	PDMP	NNP
cord-322516-wekvet6f	204	9	was	be	VBD
cord-322516-wekvet6f	204	10	surprising	surprising	JJ
cord-322516-wekvet6f	204	11	,	,	,
cord-322516-wekvet6f	204	12	as	as	IN
cord-322516-wekvet6f	204	13	we	-PRON-	PRP
cord-322516-wekvet6f	204	14	expected	expect	VBD
cord-322516-wekvet6f	204	15	that	that	IN
cord-322516-wekvet6f	204	16	if	if	IN
cord-322516-wekvet6f	204	17	we	-PRON-	PRP
cord-322516-wekvet6f	204	18	disrupted	disrupt	VBD
cord-322516-wekvet6f	204	19	its	-PRON-	PRP$
cord-322516-wekvet6f	204	20	localization	localization	NN
cord-322516-wekvet6f	204	21	,	,	,
cord-322516-wekvet6f	204	22	it	-PRON-	PRP
cord-322516-wekvet6f	204	23	would	would	MD
cord-322516-wekvet6f	204	24	move	move	VB
cord-322516-wekvet6f	204	25	with	with	IN
cord-322516-wekvet6f	204	26	"	"	``
cord-322516-wekvet6f	204	27	bulk	bulk	JJ
cord-322516-wekvet6f	204	28	flow	flow	NN
cord-322516-wekvet6f	204	29	"	"	''
cord-322516-wekvet6f	204	30	to	to	IN
cord-322516-wekvet6f	204	31	the	the	DT
cord-322516-wekvet6f	204	32	plasma	plasma	NN
cord-322516-wekvet6f	204	33	membrane	membrane	NN
cord-322516-wekvet6f	204	34	.	.	.
cord-322516-wekvet6f	205	1	That	that	IN
cord-322516-wekvet6f	205	2	IBV	IBV	NNP
cord-322516-wekvet6f	205	3	M	M	NNP
cord-322516-wekvet6f	205	4	was	be	VBD
cord-322516-wekvet6f	205	5	redistributed	redistribute	VBN
cord-322516-wekvet6f	205	6	to	to	IN
cord-322516-wekvet6f	205	7	the	the	DT
cord-322516-wekvet6f	205	8	ER	ER	NNP
cord-322516-wekvet6f	205	9	suggests	suggest	VBZ
cord-322516-wekvet6f	205	10	that	that	IN
cord-322516-wekvet6f	205	11	it	-PRON-	PRP
cord-322516-wekvet6f	205	12	has	have	VBZ
cord-322516-wekvet6f	205	13	specific	specific	JJ
cord-322516-wekvet6f	205	14	targeting	target	VBG
cord-322516-wekvet6f	205	15	information	information	NN
cord-322516-wekvet6f	205	16	for	for	IN
cord-322516-wekvet6f	205	17	retrieval	retrieval	NN
cord-322516-wekvet6f	205	18	to	to	IN
cord-322516-wekvet6f	205	19	the	the	DT
cord-322516-wekvet6f	205	20	ER	ER	NNP
cord-322516-wekvet6f	205	21	.	.	.
cord-322516-wekvet6f	206	1	Coupled	couple	VBN
cord-322516-wekvet6f	206	2	with	with	IN
cord-322516-wekvet6f	206	3	earlier	early	JJR
cord-322516-wekvet6f	206	4	work	work	NN
cord-322516-wekvet6f	206	5	in	in	IN
cord-322516-wekvet6f	206	6	our	-PRON-	PRP$
cord-322516-wekvet6f	206	7	laboratory	laboratory	NN
cord-322516-wekvet6f	206	8	on	on	IN
cord-322516-wekvet6f	206	9	the	the	DT
cord-322516-wekvet6f	206	10	role	role	NN
cord-322516-wekvet6f	206	11	of	of	IN
cord-322516-wekvet6f	206	12	oligomerization	oligomerization	NN
cord-322516-wekvet6f	206	13	of	of	IN
cord-322516-wekvet6f	206	14	IBV	IBV	NNP
cord-322516-wekvet6f	206	15	M	M	NNP
cord-322516-wekvet6f	206	16	chimeras	chimera	NNS
cord-322516-wekvet6f	206	17	in	in	IN
cord-322516-wekvet6f	206	18	CGN	CGN	NNP
cord-322516-wekvet6f	206	19	targeting	target	VBG
cord-322516-wekvet6f	207	1	(	(	-LRB-
cord-322516-wekvet6f	207	2	Weisz	Weisz	NNP
cord-322516-wekvet6f	207	3	et	et	NNP
cord-322516-wekvet6f	207	4	al	al	NNP
cord-322516-wekvet6f	207	5	.	.	.
cord-322516-wekvet6f	208	1	,	,	,
cord-322516-wekvet6f	208	2	1993	1993	CD
cord-322516-wekvet6f	208	3	)	)	-RRB-
cord-322516-wekvet6f	208	4	,	,	,
cord-322516-wekvet6f	208	5	our	-PRON-	PRP$
cord-322516-wekvet6f	208	6	findings	finding	NNS
cord-322516-wekvet6f	208	7	suggest	suggest	VBP
cord-322516-wekvet6f	208	8	that	that	IN
cord-322516-wekvet6f	208	9	IBV	IBV	NNP
cord-322516-wekvet6f	208	10	M	M	NNP
cord-322516-wekvet6f	208	11	maintains	maintain	VBZ
cord-322516-wekvet6f	208	12	its	-PRON-	PRP$
cord-322516-wekvet6f	208	13	steady	steady	JJ
cord-322516-wekvet6f	208	14	-	-	HYPH
cord-322516-wekvet6f	208	15	state	state	NN
cord-322516-wekvet6f	208	16	distribution	distribution	NN
cord-322516-wekvet6f	208	17	by	by	IN
cord-322516-wekvet6f	208	18	both	both	DT
cord-322516-wekvet6f	208	19	retention	retention	NN
cord-322516-wekvet6f	208	20	and	and	CC
cord-322516-wekvet6f	208	21	retrieval	retrieval	NN
cord-322516-wekvet6f	209	1	(	(	-LRB-
cord-322516-wekvet6f	209	2	Fig	Fig	NNP
cord-322516-wekvet6f	209	3	.	.	.
cord-322516-wekvet6f	209	4	10	10	CD
cord-322516-wekvet6f	209	5	A	a	NN
cord-322516-wekvet6f	209	6	)	)	-RRB-
cord-322516-wekvet6f	209	7	.	.	.
cord-322516-wekvet6f	210	1	We	-PRON-	PRP
cord-322516-wekvet6f	210	2	propose	propose	VBP
cord-322516-wekvet6f	210	3	two	two	CD
cord-322516-wekvet6f	210	4	models	model	NNS
cord-322516-wekvet6f	210	5	to	to	TO
cord-322516-wekvet6f	210	6	explain	explain	VB
cord-322516-wekvet6f	210	7	the	the	DT
cord-322516-wekvet6f	210	8	redistribution	redistribution	NN
cord-322516-wekvet6f	210	9	of	of	IN
cord-322516-wekvet6f	210	10	IBV	IBV	NNP
cord-322516-wekvet6f	210	11	M	M	NNP
cord-322516-wekvet6f	210	12	protein	protein	NN
cord-322516-wekvet6f	210	13	induced	induce	VBN
cord-322516-wekvet6f	210	14	by	by	IN
cord-322516-wekvet6f	210	15	PDMP	PDMP	NNP
cord-322516-wekvet6f	210	16	.	.	.
cord-322516-wekvet6f	211	1	The	the	DT
cord-322516-wekvet6f	211	2	simplest	simple	JJS
cord-322516-wekvet6f	211	3	model	model	NN
cord-322516-wekvet6f	211	4	(	(	-LRB-
cord-322516-wekvet6f	211	5	Fig	Fig	NNP
cord-322516-wekvet6f	211	6	.	.	.
cord-322516-wekvet6f	211	7	10	10	CD
cord-322516-wekvet6f	211	8	B	b	NN
cord-322516-wekvet6f	211	9	,	,	,
cord-322516-wekvet6f	211	10	left	leave	VBD
cord-322516-wekvet6f	211	11	arrow	arrow	NN
cord-322516-wekvet6f	211	12	)	)	-RRB-
cord-322516-wekvet6f	211	13	is	be	VBZ
cord-322516-wekvet6f	211	14	that	that	IN
cord-322516-wekvet6f	211	15	the	the	DT
cord-322516-wekvet6f	211	16	M	M	NNP
cord-322516-wekvet6f	211	17	protein	protein	NN
cord-322516-wekvet6f	211	18	normally	normally	RB
cord-322516-wekvet6f	211	19	cycles	cycle	VBZ
cord-322516-wekvet6f	211	20	between	between	IN
cord-322516-wekvet6f	211	21	the	the	DT
cord-322516-wekvet6f	211	22	ER	ER	NNP
cord-322516-wekvet6f	211	23	and	and	CC
cord-322516-wekvet6f	211	24	the	the	DT
cord-322516-wekvet6f	211	25	Golgi	Golgi	NNP
cord-322516-wekvet6f	211	26	at	at	IN
cord-322516-wekvet6f	211	27	a	a	DT
cord-322516-wekvet6f	211	28	significant	significant	JJ
cord-322516-wekvet6f	211	29	rate	rate	NN
cord-322516-wekvet6f	211	30	,	,	,
cord-322516-wekvet6f	211	31	as	as	IN
cord-322516-wekvet6f	211	32	has	have	VBZ
cord-322516-wekvet6f	211	33	been	be	VBN
cord-322516-wekvet6f	211	34	shown	show	VBN
cord-322516-wekvet6f	211	35	for	for	IN
cord-322516-wekvet6f	211	36	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	212	1	(	(	-LRB-
cord-322516-wekvet6f	212	2	Lippincott	Lippincott	NNP
cord-322516-wekvet6f	212	3	-	-	HYPH
cord-322516-wekvet6f	212	4	Schwartz	Schwartz	NNP
cord-322516-wekvet6f	212	5	et	et	NNP
cord-322516-wekvet6f	212	6	al	al	NNP
cord-322516-wekvet6f	212	7	.	.	.
cord-322516-wekvet6f	213	1	,	,	,
cord-322516-wekvet6f	213	2	1990	1990	CD
cord-322516-wekvet6f	213	3	;	;	:
cord-322516-wekvet6f	213	4	Schindler	Schindler	NNP
cord-322516-wekvet6f	213	5	et	et	NNP
cord-322516-wekvet6f	213	6	al	al	NNP
cord-322516-wekvet6f	213	7	.	.	NNP
cord-322516-wekvet6f	213	8	,	,	,
cord-322516-wekvet6f	213	9	1993	1993	CD
cord-322516-wekvet6f	213	10	)	)	-RRB-
cord-322516-wekvet6f	213	11	.	.	.
cord-322516-wekvet6f	214	1	The	the	DT
cord-322516-wekvet6f	214	2	slowing	slowing	NN
cord-322516-wekvet6f	214	3	of	of	IN
cord-322516-wekvet6f	214	4	anterograde	anterograde	JJ
cord-322516-wekvet6f	214	5	traffic	traffic	NN
cord-322516-wekvet6f	214	6	would	would	MD
cord-322516-wekvet6f	214	7	cause	cause	VB
cord-322516-wekvet6f	214	8	the	the	DT
cord-322516-wekvet6f	214	9	protein	protein	NN
cord-322516-wekvet6f	214	10	to	to	TO
cord-322516-wekvet6f	214	11	shift	shift	VB
cord-322516-wekvet6f	214	12	its	-PRON-	PRP$
cord-322516-wekvet6f	214	13	steady	steady	JJ
cord-322516-wekvet6f	214	14	-	-	HYPH
cord-322516-wekvet6f	214	15	state	state	NN
cord-322516-wekvet6f	214	16	distribution	distribution	NN
cord-322516-wekvet6f	214	17	to	to	IN
cord-322516-wekvet6f	214	18	the	the	DT
cord-322516-wekvet6f	214	19	ER	ER	NNP
cord-322516-wekvet6f	214	20	,	,	,
cord-322516-wekvet6f	214	21	assuming	assume	VBG
cord-322516-wekvet6f	214	22	that	that	DT
cord-322516-wekvet6f	214	23	retrograde	retrograde	JJ
cord-322516-wekvet6f	214	24	traffic	traffic	NN
cord-322516-wekvet6f	214	25	is	be	VBZ
cord-322516-wekvet6f	214	26	unaffected	unaffected	JJ
cord-322516-wekvet6f	214	27	or	or	CC
cord-322516-wekvet6f	214	28	perhaps	perhaps	RB
cord-322516-wekvet6f	214	29	increased	increase	VBN
cord-322516-wekvet6f	214	30	by	by	IN
cord-322516-wekvet6f	214	31	PDMP	PDMP	NNP
cord-322516-wekvet6f	214	32	.	.	.
cord-322516-wekvet6f	215	1	A	a	DT
cord-322516-wekvet6f	215	2	second	second	JJ
cord-322516-wekvet6f	215	3	possibility	possibility	NN
cord-322516-wekvet6f	215	4	is	be	VBZ
cord-322516-wekvet6f	215	5	that	that	IN
cord-322516-wekvet6f	215	6	PDMP	PDMP	NNP
cord-322516-wekvet6f	215	7	disrupts	disrupt	VBZ
cord-322516-wekvet6f	215	8	retention	retention	NN
cord-322516-wekvet6f	215	9	of	of	IN
cord-322516-wekvet6f	215	10	the	the	DT
cord-322516-wekvet6f	215	11	M	M	NNP
cord-322516-wekvet6f	215	12	protein	protein	NN
cord-322516-wekvet6f	215	13	,	,	,
cord-322516-wekvet6f	215	14	which	which	WDT
cord-322516-wekvet6f	215	15	then	then	RB
cord-322516-wekvet6f	215	16	cycles	cycle	VBZ
cord-322516-wekvet6f	215	17	back	back	RB
cord-322516-wekvet6f	215	18	to	to	IN
cord-322516-wekvet6f	215	19	the	the	DT
cord-322516-wekvet6f	215	20	ER	ER	NNP
cord-322516-wekvet6f	215	21	by	by	IN
cord-322516-wekvet6f	215	22	normal	normal	JJ
cord-322516-wekvet6f	215	23	retrieval	retrieval	NN
cord-322516-wekvet6f	215	24	mechanisms	mechanism	NNS
cord-322516-wekvet6f	216	1	(	(	-LRB-
cord-322516-wekvet6f	216	2	Fig	Fig	NNP
cord-322516-wekvet6f	216	3	.	.	.
cord-322516-wekvet6f	216	4	10	10	CD
cord-322516-wekvet6f	216	5	B	b	NN
cord-322516-wekvet6f	216	6	,	,	,
cord-322516-wekvet6f	216	7	right	right	JJ
cord-322516-wekvet6f	216	8	arrow	arrow	NN
cord-322516-wekvet6f	216	9	)	)	-RRB-
cord-322516-wekvet6f	216	10	.	.	.
cord-322516-wekvet6f	217	1	These	these	DT
cord-322516-wekvet6f	217	2	two	two	CD
cord-322516-wekvet6f	217	3	models	model	NNS
cord-322516-wekvet6f	217	4	are	be	VBP
cord-322516-wekvet6f	217	5	not	not	RB
cord-322516-wekvet6f	217	6	mutually	mutually	RB
cord-322516-wekvet6f	217	7	exclusive	exclusive	JJ
cord-322516-wekvet6f	217	8	,	,	,
cord-322516-wekvet6f	217	9	and	and	CC
cord-322516-wekvet6f	217	10	both	both	DT
cord-322516-wekvet6f	217	11	effects	effect	NNS
cord-322516-wekvet6f	217	12	of	of	IN
cord-322516-wekvet6f	217	13	PDMP	PDMP	NNP
cord-322516-wekvet6f	217	14	may	may	MD
cord-322516-wekvet6f	217	15	be	be	VB
cord-322516-wekvet6f	217	16	necessary	necessary	JJ
cord-322516-wekvet6f	217	17	to	to	TO
cord-322516-wekvet6f	217	18	redistribute	redistribute	VB
cord-322516-wekvet6f	217	19	IBV	IBV	NNP
cord-322516-wekvet6f	217	20	M	M	NNP
cord-322516-wekvet6f	217	21	to	to	IN
cord-322516-wekvet6f	217	22	the	the	DT
cord-322516-wekvet6f	217	23	extent	extent	NN
cord-322516-wekvet6f	217	24	observed	observe	VBN
cord-322516-wekvet6f	217	25	.	.	.
cord-322516-wekvet6f	218	1	Implicit	implicit	JJ
cord-322516-wekvet6f	218	2	in	in	IN
cord-322516-wekvet6f	218	3	both	both	DT
cord-322516-wekvet6f	218	4	models	model	NNS
cord-322516-wekvet6f	218	5	is	be	VBZ
cord-322516-wekvet6f	218	6	the	the	DT
cord-322516-wekvet6f	218	7	idea	idea	NN
cord-322516-wekvet6f	218	8	that	that	IN
cord-322516-wekvet6f	218	9	IBV	IBV	NNP
cord-322516-wekvet6f	218	10	M	M	NNP
cord-322516-wekvet6f	218	11	contains	contain	VBZ
cord-322516-wekvet6f	218	12	retrieval	retrieval	NN
cord-322516-wekvet6f	218	13	information	information	NN
cord-322516-wekvet6f	218	14	.	.	.
cord-322516-wekvet6f	219	1	PDMP	pdmp	NN
cord-322516-wekvet6f	219	2	-	-	HYPH
cord-322516-wekvet6f	219	3	induced	induce	VBN
cord-322516-wekvet6f	219	4	ER	ER	NNP
cord-322516-wekvet6f	219	5	redistribution	redistribution	NN
cord-322516-wekvet6f	219	6	was	be	VBD
cord-322516-wekvet6f	219	7	also	also	RB
cord-322516-wekvet6f	219	8	observed	observe	VBN
cord-322516-wekvet6f	219	9	for	for	IN
cord-322516-wekvet6f	219	10	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	219	11	,	,	,
cord-322516-wekvet6f	219	12	a	a	DT
cord-322516-wekvet6f	219	13	dilysine	dilysine	NN
cord-322516-wekvet6f	219	14	-	-	HYPH
cord-322516-wekvet6f	219	15	containing	contain	VBG
cord-322516-wekvet6f	219	16	IC	IC	NNP
cord-322516-wekvet6f	219	17	marker	marker	NN
cord-322516-wekvet6f	219	18	known	know	VBN
cord-322516-wekvet6f	219	19	to	to	TO
cord-322516-wekvet6f	219	20	cycle	cycle	VB
cord-322516-wekvet6f	219	21	through	through	IN
cord-322516-wekvet6f	219	22	the	the	DT
cord-322516-wekvet6f	219	23	ER	er	NN
cord-322516-wekvet6f	220	1	(	(	-LRB-
cord-322516-wekvet6f	220	2	Lippincott	Lippincott	NNP
cord-322516-wekvet6f	220	3	-	-	HYPH
cord-322516-wekvet6f	220	4	Schwartz	Schwartz	NNP
cord-322516-wekvet6f	220	5	et	et	NNP
cord-322516-wekvet6f	220	6	al	al	NNP
cord-322516-wekvet6f	220	7	.	.	.
cord-322516-wekvet6f	221	1	,	,	,
cord-322516-wekvet6f	221	2	1990	1990	CD
cord-322516-wekvet6f	221	3	;	;	:
cord-322516-wekvet6f	221	4	Schindler	Schindler	NNP
cord-322516-wekvet6f	221	5	et	et	NNP
cord-322516-wekvet6f	221	6	al	al	NNP
cord-322516-wekvet6f	221	7	.	.	NNP
cord-322516-wekvet6f	221	8	,	,	,
cord-322516-wekvet6f	221	9	1993	1993	CD
cord-322516-wekvet6f	221	10	)	)	-RRB-
cord-322516-wekvet6f	221	11	.	.	.
cord-322516-wekvet6f	222	1	Double	double	JJ
cord-322516-wekvet6f	222	2	-	-	HYPH
cord-322516-wekvet6f	222	3	label	label	NN
cord-322516-wekvet6f	222	4	immunoelectron	immunoelectron	NNP
cord-322516-wekvet6f	222	5	microscopy	microscopy	NN
cord-322516-wekvet6f	222	6	in	in	IN
cord-322516-wekvet6f	222	7	HeLa	HeLa	NNP
cord-322516-wekvet6f	222	8	cells	cell	NNS
cord-322516-wekvet6f	222	9	showed	show	VBD
cord-322516-wekvet6f	222	10	that	that	IN
cord-322516-wekvet6f	222	11	the	the	DT
cord-322516-wekvet6f	222	12	distri	distri	NN
cord-322516-wekvet6f	222	13	-	-	HYPH
cord-322516-wekvet6f	222	14	bution	bution	NN
cord-322516-wekvet6f	222	15	of	of	IN
cord-322516-wekvet6f	222	16	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	222	17	and	and	CC
cord-322516-wekvet6f	222	18	IBV	IBV	NNP
cord-322516-wekvet6f	222	19	M	M	NNP
cord-322516-wekvet6f	222	20	overlapped	overlap	VBD
cord-322516-wekvet6f	222	21	significantly	significantly	RB
cord-322516-wekvet6f	222	22	,	,	,
cord-322516-wekvet6f	222	23	though	though	IN
cord-322516-wekvet6f	222	24	not	not	RB
cord-322516-wekvet6f	222	25	completely	completely	RB
cord-322516-wekvet6f	222	26	(	(	-LRB-
cord-322516-wekvet6f	222	27	Sodeik	Sodeik	NNP
cord-322516-wekvet6f	222	28	et	et	FW
cord-322516-wekvet6f	222	29	al	al	NNP
cord-322516-wekvet6f	222	30	.	.	NNP
cord-322516-wekvet6f	222	31	,	,	,
cord-322516-wekvet6f	222	32	1993	1993	CD
cord-322516-wekvet6f	222	33	)	)	-RRB-
cord-322516-wekvet6f	222	34	.	.	.
cord-322516-wekvet6f	223	1	This	this	DT
cord-322516-wekvet6f	223	2	suggests	suggest	VBZ
cord-322516-wekvet6f	223	3	that	that	IN
cord-322516-wekvet6f	223	4	IBV	IBV	NNP
cord-322516-wekvet6f	223	5	M	M	NNP
cord-322516-wekvet6f	223	6	may	may	MD
cord-322516-wekvet6f	223	7	in	in	IN
cord-322516-wekvet6f	223	8	part	part	NN
cord-322516-wekvet6f	223	9	use	use	VB
cord-322516-wekvet6f	223	10	the	the	DT
cord-322516-wekvet6f	223	11	same	same	JJ
cord-322516-wekvet6f	223	12	,	,	,
cord-322516-wekvet6f	223	13	as	as	IN
cord-322516-wekvet6f	223	14	yet	yet	RB
cord-322516-wekvet6f	223	15	unknown	unknown	JJ
cord-322516-wekvet6f	223	16	,	,	,
cord-322516-wekvet6f	223	17	cellular	cellular	JJ
cord-322516-wekvet6f	223	18	machinery	machinery	NN
cord-322516-wekvet6f	223	19	used	use	VBN
cord-322516-wekvet6f	223	20	by	by	IN
cord-322516-wekvet6f	223	21	IC	IC	NNP
cord-322516-wekvet6f	223	22	proteins	protein	NNS
cord-322516-wekvet6f	223	23	to	to	TO
cord-322516-wekvet6f	223	24	maintain	maintain	VB
cord-322516-wekvet6f	223	25	its	-PRON-	PRP$
cord-322516-wekvet6f	223	26	steadystate	steadystate	NN
cord-322516-wekvet6f	223	27	localization	localization	NN
cord-322516-wekvet6f	223	28	.	.	.
cord-322516-wekvet6f	224	1	Using	use	VBG
cord-322516-wekvet6f	224	2	deletion	deletion	NN
cord-322516-wekvet6f	224	3	mutants	mutant	NNS
cord-322516-wekvet6f	224	4	and	and	CC
cord-322516-wekvet6f	224	5	chimeric	chimeric	JJ
cord-322516-wekvet6f	224	6	molecules	molecule	NNS
cord-322516-wekvet6f	224	7	,	,	,
cord-322516-wekvet6f	224	8	dissection	dissection	NN
cord-322516-wekvet6f	224	9	of	of	IN
cord-322516-wekvet6f	224	10	IBV	IBV	NNP
cord-322516-wekvet6f	224	11	M	M	NNP
cord-322516-wekvet6f	224	12	retention	retention	NN
cord-322516-wekvet6f	224	13	and	and	CC
cord-322516-wekvet6f	224	14	retrieval	retrieval	NN
cord-322516-wekvet6f	224	15	information	information	NN
cord-322516-wekvet6f	224	16	should	should	MD
cord-322516-wekvet6f	224	17	be	be	VB
cord-322516-wekvet6f	224	18	possible	possible	JJ
cord-322516-wekvet6f	224	19	using	use	VBG
cord-322516-wekvet6f	224	20	PDMP	PDMP	NNP
cord-322516-wekvet6f	224	21	as	as	IN
cord-322516-wekvet6f	224	22	a	a	DT
cord-322516-wekvet6f	224	23	tool	tool	NN
cord-322516-wekvet6f	224	24	.	.	.
cord-322516-wekvet6f	225	1	The	the	DT
cord-322516-wekvet6f	225	2	pathway	pathway	NN
cord-322516-wekvet6f	225	3	followed	follow	VBN
cord-322516-wekvet6f	225	4	by	by	IN
cord-322516-wekvet6f	225	5	IBV	IBV	NNP
cord-322516-wekvet6f	225	6	M	M	NNP
cord-322516-wekvet6f	225	7	during	during	IN
cord-322516-wekvet6f	225	8	retrieval	retrieval	NN
cord-322516-wekvet6f	225	9	will	will	MD
cord-322516-wekvet6f	225	10	also	also	RB
cord-322516-wekvet6f	225	11	be	be	VB
cord-322516-wekvet6f	225	12	important	important	JJ
cord-322516-wekvet6f	225	13	to	to	TO
cord-322516-wekvet6f	225	14	decipher	decipher	VB
cord-322516-wekvet6f	225	15	.	.	.
cord-322516-wekvet6f	226	1	Experiments	experiment	NNS
cord-322516-wekvet6f	226	2	in	in	IN
cord-322516-wekvet6f	226	3	nontreated	nontreated	JJ
cord-322516-wekvet6f	226	4	cells	cell	NNS
cord-322516-wekvet6f	226	5	suggest	suggest	VBP
cord-322516-wekvet6f	226	6	that	that	IN
cord-322516-wekvet6f	226	7	the	the	DT
cord-322516-wekvet6f	226	8	protein	protein	NN
cord-322516-wekvet6f	226	9	may	may	MD
cord-322516-wekvet6f	226	10	move	move	VB
cord-322516-wekvet6f	226	11	through	through	IN
cord-322516-wekvet6f	226	12	later	later	JJ
cord-322516-wekvet6f	226	13	Golgi	Golgi	NNP
cord-322516-wekvet6f	226	14	compartments	compartment	NNS
cord-322516-wekvet6f	226	15	even	even	RB
cord-322516-wekvet6f	226	16	though	though	IN
cord-322516-wekvet6f	226	17	its	-PRON-	PRP$
cord-322516-wekvet6f	226	18	steady	steady	JJ
cord-322516-wekvet6f	226	19	-	-	HYPH
cord-322516-wekvet6f	226	20	state	state	NN
cord-322516-wekvet6f	226	21	distribution	distribution	NN
cord-322516-wekvet6f	226	22	is	be	VBZ
cord-322516-wekvet6f	226	23	the	the	DT
cord-322516-wekvet6f	226	24	CGN	CGN	NNP
cord-322516-wekvet6f	226	25	,	,	,
cord-322516-wekvet6f	226	26	because	because	IN
cord-322516-wekvet6f	226	27	its	-PRON-	PRP$
cord-322516-wekvet6f	226	28	oligosaccharides	oligosaccharide	NNS
cord-322516-wekvet6f	226	29	are	be	VBP
cord-322516-wekvet6f	226	30	slowly	slowly	RB
cord-322516-wekvet6f	226	31	processed	process	VBN
cord-322516-wekvet6f	226	32	(	(	-LRB-
cord-322516-wekvet6f	226	33	Machamer	Machamer	NNP
cord-322516-wekvet6f	226	34	et	et	NNP
cord-322516-wekvet6f	226	35	al	al	NNP
cord-322516-wekvet6f	226	36	.	.	NNP
cord-322516-wekvet6f	226	37	,	,	,
cord-322516-wekvet6f	226	38	1990	1990	CD
cord-322516-wekvet6f	226	39	)	)	-RRB-
cord-322516-wekvet6f	226	40	.	.	.
cord-322516-wekvet6f	227	1	Interestingly	interestingly	RB
cord-322516-wekvet6f	227	2	,	,	,
cord-322516-wekvet6f	227	3	we	-PRON-	PRP
cord-322516-wekvet6f	227	4	did	do	VBD
cord-322516-wekvet6f	227	5	not	not	RB
cord-322516-wekvet6f	227	6	observe	observe	VB
cord-322516-wekvet6f	227	7	redistribution	redistribution	NN
cord-322516-wekvet6f	227	8	of	of	IN
cord-322516-wekvet6f	227	9	two	two	CD
cord-322516-wekvet6f	227	10	Golgi	Golgi	NNP
cord-322516-wekvet6f	227	11	stack	stack	NN
cord-322516-wekvet6f	227	12	markers	marker	NNS
cord-322516-wekvet6f	227	13	(	(	-LRB-
cord-322516-wekvet6f	227	14	Man	Man	NNP
cord-322516-wekvet6f	227	15	II	II	NNP
cord-322516-wekvet6f	227	16	and	and	CC
cord-322516-wekvet6f	227	17	giantin	giantin	NNP
cord-322516-wekvet6f	227	18	)	)	-RRB-
cord-322516-wekvet6f	227	19	to	to	IN
cord-322516-wekvet6f	227	20	the	the	DT
cord-322516-wekvet6f	227	21	ER	ER	NNP
cord-322516-wekvet6f	227	22	with	with	IN
cord-322516-wekvet6f	227	23	PDMP	PDMP	NNP
cord-322516-wekvet6f	227	24	treatment	treatment	NN
cord-322516-wekvet6f	227	25	.	.	.
cord-322516-wekvet6f	228	1	Golgi	golgi	NN
cord-322516-wekvet6f	228	2	membrane	membrane	NN
cord-322516-wekvet6f	228	3	proteins	protein	NNS
cord-322516-wekvet6f	228	4	were	be	VBD
cord-322516-wekvet6f	228	5	recently	recently	RB
cord-322516-wekvet6f	228	6	suggested	suggest	VBN
cord-322516-wekvet6f	228	7	to	to	TO
cord-322516-wekvet6f	228	8	be	be	VB
cord-322516-wekvet6f	228	9	highly	highly	RB
cord-322516-wekvet6f	228	10	mobile	mobile	JJ
cord-322516-wekvet6f	228	11	(	(	-LRB-
cord-322516-wekvet6f	228	12	Cole	Cole	NNP
cord-322516-wekvet6f	228	13	et	et	NNP
cord-322516-wekvet6f	228	14	al	al	NNP
cord-322516-wekvet6f	228	15	.	.	NNP
cord-322516-wekvet6f	228	16	,	,	,
cord-322516-wekvet6f	228	17	1996b	1996b	CD
cord-322516-wekvet6f	228	18	)	)	-RRB-
cord-322516-wekvet6f	228	19	and	and	CC
cord-322516-wekvet6f	228	20	to	to	TO
cord-322516-wekvet6f	228	21	cycle	cycle	VB
cord-322516-wekvet6f	228	22	through	through	IN
cord-322516-wekvet6f	228	23	the	the	DT
cord-322516-wekvet6f	228	24	ER	er	NN
cord-322516-wekvet6f	229	1	(	(	-LRB-
cord-322516-wekvet6f	229	2	Cole	Cole	NNP
cord-322516-wekvet6f	229	3	et	et	NNP
cord-322516-wekvet6f	229	4	al	al	NNP
cord-322516-wekvet6f	229	5	.	.	NNP
cord-322516-wekvet6f	229	6	,	,	,
cord-322516-wekvet6f	229	7	1996a	1996a	CD
cord-322516-wekvet6f	229	8	)	)	-RRB-
cord-322516-wekvet6f	229	9	.	.	.
cord-322516-wekvet6f	230	1	Our	-PRON-	PRP$
cord-322516-wekvet6f	230	2	results	result	NNS
cord-322516-wekvet6f	230	3	with	with	IN
cord-322516-wekvet6f	230	4	PDMP	PDMP	NNP
cord-322516-wekvet6f	230	5	suggest	suggest	VBP
cord-322516-wekvet6f	230	6	that	that	IN
cord-322516-wekvet6f	230	7	cycling	cycling	NN
cord-322516-wekvet6f	230	8	of	of	IN
cord-322516-wekvet6f	230	9	these	these	DT
cord-322516-wekvet6f	230	10	proteins	protein	NNS
cord-322516-wekvet6f	230	11	does	do	VBZ
cord-322516-wekvet6f	230	12	not	not	RB
cord-322516-wekvet6f	230	13	occur	occur	VB
cord-322516-wekvet6f	230	14	during	during	IN
cord-322516-wekvet6f	230	15	the	the	DT
cord-322516-wekvet6f	230	16	time	time	NN
cord-322516-wekvet6f	230	17	scale	scale	NN
cord-322516-wekvet6f	230	18	of	of	IN
cord-322516-wekvet6f	230	19	our	-PRON-	PRP$
cord-322516-wekvet6f	230	20	experiments	experiment	NNS
cord-322516-wekvet6f	230	21	,	,	,
cord-322516-wekvet6f	230	22	and/or	and/or	CC
cord-322516-wekvet6f	230	23	that	that	IN
cord-322516-wekvet6f	230	24	its	-PRON-	PRP$
cord-322516-wekvet6f	230	25	predominant	predominant	JJ
cord-322516-wekvet6f	230	26	effect	effect	NN
cord-322516-wekvet6f	230	27	on	on	IN
cord-322516-wekvet6f	230	28	IBV	IBV	NNP
cord-322516-wekvet6f	230	29	M	M	NNP
cord-322516-wekvet6f	230	30	is	be	VBZ
cord-322516-wekvet6f	230	31	a	a	DT
cord-322516-wekvet6f	230	32	loss	loss	NN
cord-322516-wekvet6f	230	33	of	of	IN
cord-322516-wekvet6f	230	34	retention	retention	NN
cord-322516-wekvet6f	230	35	.	.	.
cord-322516-wekvet6f	231	1	Interestingly	interestingly	RB
cord-322516-wekvet6f	231	2	,	,	,
cord-322516-wekvet6f	231	3	it	-PRON-	PRP
cord-322516-wekvet6f	231	4	has	have	VBZ
cord-322516-wekvet6f	231	5	been	be	VBN
cord-322516-wekvet6f	231	6	shown	show	VBN
cord-322516-wekvet6f	231	7	that	that	IN
cord-322516-wekvet6f	231	8	myriocin	myriocin	NNS
cord-322516-wekvet6f	231	9	,	,	,
cord-322516-wekvet6f	231	10	an	an	DT
cord-322516-wekvet6f	231	11	inhibitor	inhibitor	NN
cord-322516-wekvet6f	231	12	of	of	IN
cord-322516-wekvet6f	231	13	sphingolipid	sphingolipid	NNP
cord-322516-wekvet6f	231	14	synthesis	synthesis	NNP
cord-322516-wekvet6f	231	15	thought	think	VBD
cord-322516-wekvet6f	231	16	to	to	TO
cord-322516-wekvet6f	231	17	inhibit	inhibit	VB
cord-322516-wekvet6f	231	18	the	the	DT
cord-322516-wekvet6f	231	19	same	same	JJ
cord-322516-wekvet6f	231	20	step	step	NN
cord-322516-wekvet6f	231	21	as	as	IN
cord-322516-wekvet6f	231	22	␤	␤	NNP
cord-322516-wekvet6f	231	23	CA	CA	NNP
cord-322516-wekvet6f	231	24	,	,	,
cord-322516-wekvet6f	231	25	reduces	reduce	VBZ
cord-322516-wekvet6f	231	26	the	the	DT
cord-322516-wekvet6f	231	27	rate	rate	NN
cord-322516-wekvet6f	231	28	of	of	IN
cord-322516-wekvet6f	231	29	transport	transport	NN
cord-322516-wekvet6f	231	30	of	of	IN
cord-322516-wekvet6f	231	31	a	a	DT
cord-322516-wekvet6f	231	32	glycosylphosphatidylinositol	glycosylphosphatidylinositol	NN
cord-322516-wekvet6f	231	33	-	-	HYPH
cord-322516-wekvet6f	231	34	linked	link	VBN
cord-322516-wekvet6f	231	35	protein	protein	NN
cord-322516-wekvet6f	231	36	but	but	CC
cord-322516-wekvet6f	231	37	not	not	RB
cord-322516-wekvet6f	231	38	other	other	JJ
cord-322516-wekvet6f	231	39	proteins	protein	NNS
cord-322516-wekvet6f	231	40	out	out	IN
cord-322516-wekvet6f	231	41	of	of	IN
cord-322516-wekvet6f	231	42	the	the	DT
cord-322516-wekvet6f	231	43	ER	ER	NNP
cord-322516-wekvet6f	231	44	in	in	IN
cord-322516-wekvet6f	231	45	yeast	yeast	NN
cord-322516-wekvet6f	232	1	(	(	-LRB-
cord-322516-wekvet6f	232	2	Horvath	Horvath	NNP
cord-322516-wekvet6f	232	3	et	et	NNP
cord-322516-wekvet6f	232	4	al	al	NNP
cord-322516-wekvet6f	232	5	.	.	NNP
cord-322516-wekvet6f	232	6	,	,	,
cord-322516-wekvet6f	232	7	1994	1994	CD
cord-322516-wekvet6f	232	8	)	)	-RRB-
cord-322516-wekvet6f	232	9	.	.	.
cord-322516-wekvet6f	233	1	It	-PRON-	PRP
cord-322516-wekvet6f	233	2	would	would	MD
cord-322516-wekvet6f	233	3	be	be	VB
cord-322516-wekvet6f	233	4	interesting	interesting	JJ
cord-322516-wekvet6f	233	5	to	to	TO
cord-322516-wekvet6f	233	6	test	test	VB
cord-322516-wekvet6f	233	7	whether	whether	IN
cord-322516-wekvet6f	233	8	inhibition	inhibition	NN
cord-322516-wekvet6f	233	9	of	of	IN
cord-322516-wekvet6f	233	10	ceramide	ceramide	NN
cord-322516-wekvet6f	233	11	synthesis	synthesis	NN
cord-322516-wekvet6f	233	12	in	in	IN
cord-322516-wekvet6f	233	13	mammalian	mammalian	JJ
cord-322516-wekvet6f	233	14	cells	cell	NNS
cord-322516-wekvet6f	233	15	also	also	RB
cord-322516-wekvet6f	233	16	slows	slow	VBZ
cord-322516-wekvet6f	233	17	the	the	DT
cord-322516-wekvet6f	233	18	rate	rate	NN
cord-322516-wekvet6f	233	19	of	of	IN
cord-322516-wekvet6f	233	20	transport	transport	NN
cord-322516-wekvet6f	233	21	of	of	IN
cord-322516-wekvet6f	233	22	glycosylphosphatidylinositol	glycosylphosphatidylinositol	NNP
cord-322516-wekvet6f	233	23	-	-	HYPH
cord-322516-wekvet6f	233	24	linked	link	VBN
cord-322516-wekvet6f	233	25	proteins	protein	NNS
cord-322516-wekvet6f	233	26	in	in	IN
cord-322516-wekvet6f	233	27	mammalian	mammalian	JJ
cord-322516-wekvet6f	233	28	cells	cell	NNS
cord-322516-wekvet6f	233	29	.	.	.
cord-322516-wekvet6f	234	1	However	however	RB
cord-322516-wekvet6f	234	2	,	,	,
cord-322516-wekvet6f	234	3	neither	neither	CC
cord-322516-wekvet6f	234	4	␤	␤	NNP
cord-322516-wekvet6f	234	5	CA	CA	NNP
cord-322516-wekvet6f	234	6	nor	nor	CC
cord-322516-wekvet6f	234	7	FB1	FB1	NNP
cord-322516-wekvet6f	234	8	had	have	VBD
cord-322516-wekvet6f	234	9	an	an	DT
cord-322516-wekvet6f	234	10	effect	effect	NN
cord-322516-wekvet6f	234	11	on	on	IN
cord-322516-wekvet6f	234	12	the	the	DT
cord-322516-wekvet6f	234	13	rate	rate	NN
cord-322516-wekvet6f	234	14	of	of	IN
cord-322516-wekvet6f	234	15	anterograde	anterograde	JJ
cord-322516-wekvet6f	234	16	traffic	traffic	NN
cord-322516-wekvet6f	234	17	of	of	IN
cord-322516-wekvet6f	234	18	VSV	VSV	NNP
cord-322516-wekvet6f	234	19	G	G	NNP
cord-322516-wekvet6f	234	20	or	or	CC
cord-322516-wekvet6f	234	21	the	the	DT
cord-322516-wekvet6f	234	22	localization	localization	NN
cord-322516-wekvet6f	234	23	of	of	IN
cord-322516-wekvet6f	234	24	IC	IC	NNP
cord-322516-wekvet6f	234	25	,	,	,
cord-322516-wekvet6f	234	26	CGN	CGN	NNP
cord-322516-wekvet6f	234	27	,	,	,
cord-322516-wekvet6f	234	28	or	or	CC
cord-322516-wekvet6f	234	29	Golgi	Golgi	NNP
cord-322516-wekvet6f	234	30	stack	stack	NN
cord-322516-wekvet6f	234	31	proteins	protein	NNS
cord-322516-wekvet6f	234	32	.	.	.
cord-322516-wekvet6f	235	1	When	when	WRB
cord-322516-wekvet6f	235	2	we	-PRON-	PRP
cord-322516-wekvet6f	235	3	quantified	quantify	VBD
cord-322516-wekvet6f	235	4	the	the	DT
cord-322516-wekvet6f	235	5	effects	effect	NNS
cord-322516-wekvet6f	235	6	of	of	IN
cord-322516-wekvet6f	235	7	these	these	DT
cord-322516-wekvet6f	235	8	two	two	CD
cord-322516-wekvet6f	235	9	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	235	10	on	on	IN
cord-322516-wekvet6f	235	11	the	the	DT
cord-322516-wekvet6f	235	12	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	235	13	Figure	figure	NN
cord-322516-wekvet6f	235	14	9	9	CD
cord-322516-wekvet6f	235	15	.	.	.
cord-322516-wekvet6f	236	1	Exogenous	exogenous	JJ
cord-322516-wekvet6f	236	2	C	C	NNP
cord-322516-wekvet6f	236	3	6	6	CD
cord-322516-wekvet6f	236	4	Cer	Cer	NNP
cord-322516-wekvet6f	236	5	did	do	VBD
cord-322516-wekvet6f	236	6	not	not	RB
cord-322516-wekvet6f	236	7	redistribute	redistribute	VB
cord-322516-wekvet6f	236	8	IBV	IBV	NNP
cord-322516-wekvet6f	236	9	M	M	NNP
cord-322516-wekvet6f	236	10	or	or	CC
cord-322516-wekvet6f	236	11	ER	ER	NNP
cord-322516-wekvet6f	236	12	-	-	HYPH
cord-322516-wekvet6f	236	13	GIC-53	GIC-53	NNP
cord-322516-wekvet6f	236	14	.	.	.
cord-322516-wekvet6f	237	1	BHK	BHK	NNP
cord-322516-wekvet6f	237	2	cells	cell	NNS
cord-322516-wekvet6f	237	3	(	(	-LRB-
cord-322516-wekvet6f	237	4	IBV	IBV	NNP
cord-322516-wekvet6f	237	5	M	M	NNP
cord-322516-wekvet6f	237	6	,	,	,
cord-322516-wekvet6f	237	7	Man	Man	NNP
cord-322516-wekvet6f	237	8	II	II	NNP
cord-322516-wekvet6f	237	9	,	,	,
cord-322516-wekvet6f	237	10	and	and	CC
cord-322516-wekvet6f	237	11	␤	␤	NNP
cord-322516-wekvet6f	237	12	-COP	-COP	JJR
cord-322516-wekvet6f	237	13	)	)	-RRB-
cord-322516-wekvet6f	237	14	or	or	CC
cord-322516-wekvet6f	237	15	Vero	Vero	NNP
cord-322516-wekvet6f	237	16	cells	cell	NNS
cord-322516-wekvet6f	237	17	(	(	-LRB-
cord-322516-wekvet6f	237	18	ERGIC-53	ergic-53	CD
cord-322516-wekvet6f	237	19	)	)	-RRB-
cord-322516-wekvet6f	237	20	were	be	VBD
cord-322516-wekvet6f	237	21	infected	infect	VBN
cord-322516-wekvet6f	237	22	with	with	IN
cord-322516-wekvet6f	237	23	a	a	DT
cord-322516-wekvet6f	237	24	recombinant	recombinant	JJ
cord-322516-wekvet6f	237	25	vaccinia	vaccinia	NN
cord-322516-wekvet6f	237	26	virus	virus	NN
cord-322516-wekvet6f	237	27	expressing	express	VBG
cord-322516-wekvet6f	237	28	IBV	IBV	NNP
cord-322516-wekvet6f	237	29	M.	M.	NNP
cord-322516-wekvet6f	237	30	4	4	CD
cord-322516-wekvet6f	237	31	h	h	NN
cord-322516-wekvet6f	237	32	after	after	IN
cord-322516-wekvet6f	237	33	infection	infection	NN
cord-322516-wekvet6f	237	34	the	the	DT
cord-322516-wekvet6f	237	35	cells	cell	NNS
cord-322516-wekvet6f	237	36	were	be	VBD
cord-322516-wekvet6f	237	37	treated	treat	VBN
cord-322516-wekvet6f	237	38	with	with	IN
cord-322516-wekvet6f	237	39	50	50	CD
cord-322516-wekvet6f	237	40	g	g	NN
cord-322516-wekvet6f	237	41	/	/	SYM
cord-322516-wekvet6f	237	42	ml	ml	NN
cord-322516-wekvet6f	237	43	cycloheximide	cycloheximide	NN
cord-322516-wekvet6f	237	44	.	.	.
cord-322516-wekvet6f	238	1	At	at	IN
cord-322516-wekvet6f	238	2	5	5	CD
cord-322516-wekvet6f	238	3	h	h	NN
cord-322516-wekvet6f	238	4	after	after	IN
cord-322516-wekvet6f	238	5	infection	infection	NN
cord-322516-wekvet6f	238	6	cells	cell	NNS
cord-322516-wekvet6f	238	7	were	be	VBD
cord-322516-wekvet6f	238	8	incubated	incubate	VBN
cord-322516-wekvet6f	238	9	for	for	IN
cord-322516-wekvet6f	238	10	1	1	CD
cord-322516-wekvet6f	238	11	h	h	NN
cord-322516-wekvet6f	238	12	in	in	IN
cord-322516-wekvet6f	238	13	serum	serum	NN
cord-322516-wekvet6f	238	14	-	-	HYPH
cord-322516-wekvet6f	238	15	free	free	JJ
cord-322516-wekvet6f	238	16	DME	DME	NNP
cord-322516-wekvet6f	238	17	with	with	IN
cord-322516-wekvet6f	238	18	0.34	0.34	CD
cord-322516-wekvet6f	238	19	mg	mg	NNP
cord-322516-wekvet6f	238	20	/	/	SYM
cord-322516-wekvet6f	238	21	ml	ml	NN
cord-322516-wekvet6f	238	22	defatted	defatte	VBD
cord-322516-wekvet6f	238	23	BSA	BSA	NNP
cord-322516-wekvet6f	238	24	with	with	IN
cord-322516-wekvet6f	238	25	or	or	CC
cord-322516-wekvet6f	238	26	without	without	IN
cord-322516-wekvet6f	238	27	25	25	CD
cord-322516-wekvet6f	238	28	M	M	NNP
cord-322516-wekvet6f	238	29	C	C	NNP
cord-322516-wekvet6f	238	30	6	6	CD
cord-322516-wekvet6f	238	31	Cer	cer	NN
cord-322516-wekvet6f	238	32	.	.	.
cord-322516-wekvet6f	239	1	Cells	cell	NNS
cord-322516-wekvet6f	239	2	were	be	VBD
cord-322516-wekvet6f	239	3	then	then	RB
cord-322516-wekvet6f	239	4	prepared	prepare	VBN
cord-322516-wekvet6f	239	5	for	for	IN
cord-322516-wekvet6f	239	6	indirect	indirect	JJ
cord-322516-wekvet6f	239	7	immunofluorescence	immunofluorescence	NN
cord-322516-wekvet6f	239	8	and	and	CC
cord-322516-wekvet6f	239	9	stained	stain	VBN
cord-322516-wekvet6f	239	10	with	with	IN
cord-322516-wekvet6f	239	11	the	the	DT
cord-322516-wekvet6f	239	12	indicated	indicate	VBN
cord-322516-wekvet6f	239	13	antibodies	antibody	NNS
cord-322516-wekvet6f	239	14	.	.	.
cord-322516-wekvet6f	240	1	For	for	IN
cord-322516-wekvet6f	240	2	each	each	DT
cord-322516-wekvet6f	240	3	experimental	experimental	JJ
cord-322516-wekvet6f	240	4	series	series	NN
cord-322516-wekvet6f	240	5	,	,	,
cord-322516-wekvet6f	240	6	the	the	DT
cord-322516-wekvet6f	240	7	Nomarski	Nomarski	NNP
cord-322516-wekvet6f	240	8	image	image	NN
cord-322516-wekvet6f	240	9	is	be	VBZ
cord-322516-wekvet6f	240	10	shown	show	VBN
cord-322516-wekvet6f	240	11	on	on	IN
cord-322516-wekvet6f	240	12	the	the	DT
cord-322516-wekvet6f	240	13	left	left	NN
cord-322516-wekvet6f	240	14	and	and	CC
cord-322516-wekvet6f	240	15	the	the	DT
cord-322516-wekvet6f	240	16	fluorescence	fluorescence	NN
cord-322516-wekvet6f	240	17	image	image	NN
cord-322516-wekvet6f	240	18	on	on	IN
cord-322516-wekvet6f	240	19	the	the	DT
cord-322516-wekvet6f	240	20	right	right	NN
cord-322516-wekvet6f	240	21	.	.	.
cord-322516-wekvet6f	241	1	Bar	bar	NN
cord-322516-wekvet6f	241	2	,	,	,
cord-322516-wekvet6f	241	3	10	10	CD
cord-322516-wekvet6f	241	4	m.	m.	NN
cord-322516-wekvet6f	241	5	Figure	Figure	NNP
cord-322516-wekvet6f	241	6	10	10	CD
cord-322516-wekvet6f	241	7	.	.	.
cord-322516-wekvet6f	242	1	Current	current	JJ
cord-322516-wekvet6f	242	2	models	model	NNS
cord-322516-wekvet6f	242	3	for	for	IN
cord-322516-wekvet6f	242	4	how	how	WRB
cord-322516-wekvet6f	242	5	IBV	IBV	NNP
cord-322516-wekvet6f	242	6	M	M	NNP
cord-322516-wekvet6f	242	7	maintains	maintain	VBZ
cord-322516-wekvet6f	242	8	its	-PRON-	PRP$
cord-322516-wekvet6f	242	9	steady	steady	JJ
cord-322516-wekvet6f	242	10	-	-	HYPH
cord-322516-wekvet6f	242	11	state	state	NN
cord-322516-wekvet6f	242	12	distribution	distribution	NN
cord-322516-wekvet6f	242	13	and	and	CC
cord-322516-wekvet6f	242	14	how	how	WRB
cord-322516-wekvet6f	242	15	PDMP	PDMP	NNP
cord-322516-wekvet6f	242	16	might	may	MD
cord-322516-wekvet6f	242	17	alter	alter	VB
cord-322516-wekvet6f	242	18	this	this	DT
cord-322516-wekvet6f	242	19	distribution	distribution	NN
cord-322516-wekvet6f	242	20	.	.	.
cord-322516-wekvet6f	243	1	(	(	-LRB-
cord-322516-wekvet6f	243	2	A	a	NN
cord-322516-wekvet6f	243	3	)	)	-RRB-
cord-322516-wekvet6f	243	4	Evidence	evidence	NN
cord-322516-wekvet6f	243	5	presented	present	VBN
cord-322516-wekvet6f	243	6	here	here	RB
cord-322516-wekvet6f	243	7	shows	show	VBZ
cord-322516-wekvet6f	243	8	that	that	IN
cord-322516-wekvet6f	243	9	IBV	IBV	NNP
cord-322516-wekvet6f	243	10	M	M	NNP
cord-322516-wekvet6f	243	11	can	can	MD
cord-322516-wekvet6f	243	12	be	be	VB
cord-322516-wekvet6f	243	13	induced	induce	VBN
cord-322516-wekvet6f	243	14	to	to	TO
cord-322516-wekvet6f	243	15	redistribute	redistribute	VB
cord-322516-wekvet6f	243	16	to	to	IN
cord-322516-wekvet6f	243	17	the	the	DT
cord-322516-wekvet6f	243	18	ER	ER	NNP
cord-322516-wekvet6f	243	19	,	,	,
cord-322516-wekvet6f	243	20	indicating	indicate	VBG
cord-322516-wekvet6f	243	21	that	that	IN
cord-322516-wekvet6f	243	22	IBV	IBV	NNP
cord-322516-wekvet6f	243	23	M	M	NNP
cord-322516-wekvet6f	243	24	has	have	VBZ
cord-322516-wekvet6f	243	25	information	information	NN
cord-322516-wekvet6f	243	26	necessary	necessary	JJ
cord-322516-wekvet6f	243	27	for	for	IN
cord-322516-wekvet6f	243	28	traffic	traffic	NN
cord-322516-wekvet6f	243	29	to	to	IN
cord-322516-wekvet6f	243	30	the	the	DT
cord-322516-wekvet6f	243	31	ER	ER	NNP
cord-322516-wekvet6f	243	32	.	.	.
cord-322516-wekvet6f	244	1	We	-PRON-	PRP
cord-322516-wekvet6f	244	2	propose	propose	VBP
cord-322516-wekvet6f	244	3	that	that	IN
cord-322516-wekvet6f	244	4	IBV	IBV	NNP
cord-322516-wekvet6f	244	5	M	M	NNP
cord-322516-wekvet6f	244	6	normally	normally	RB
cord-322516-wekvet6f	244	7	maintains	maintain	VBZ
cord-322516-wekvet6f	244	8	its	-PRON-	PRP$
cord-322516-wekvet6f	244	9	steady	steady	JJ
cord-322516-wekvet6f	244	10	-	-	HYPH
cord-322516-wekvet6f	244	11	state	state	NN
cord-322516-wekvet6f	244	12	distribution	distribution	NN
cord-322516-wekvet6f	244	13	by	by	IN
cord-322516-wekvet6f	244	14	cycling	cycle	VBG
cord-322516-wekvet6f	244	15	through	through	IN
cord-322516-wekvet6f	244	16	the	the	DT
cord-322516-wekvet6f	244	17	ER	ER	NNP
cord-322516-wekvet6f	244	18	at	at	IN
cord-322516-wekvet6f	244	19	some	some	DT
cord-322516-wekvet6f	244	20	basal	basal	NN
cord-322516-wekvet6f	244	21	rate	rate	NN
cord-322516-wekvet6f	244	22	.	.	.
cord-322516-wekvet6f	245	1	(	(	-LRB-
cord-322516-wekvet6f	245	2	B	b	NN
cord-322516-wekvet6f	245	3	)	)	-RRB-
cord-322516-wekvet6f	245	4	If	if	IN
cord-322516-wekvet6f	245	5	IBV	IBV	NNP
cord-322516-wekvet6f	245	6	M	M	NNP
cord-322516-wekvet6f	245	7	is	be	VBZ
cord-322516-wekvet6f	245	8	cycling	cycle	VBG
cord-322516-wekvet6f	245	9	through	through	IN
cord-322516-wekvet6f	245	10	the	the	DT
cord-322516-wekvet6f	245	11	ER	ER	NNP
cord-322516-wekvet6f	245	12	normally	normally	RB
cord-322516-wekvet6f	245	13	,	,	,
cord-322516-wekvet6f	245	14	then	then	RB
cord-322516-wekvet6f	245	15	its	-PRON-	PRP$
cord-322516-wekvet6f	245	16	localization	localization	NN
cord-322516-wekvet6f	245	17	would	would	MD
cord-322516-wekvet6f	245	18	depend	depend	VB
cord-322516-wekvet6f	245	19	on	on	IN
cord-322516-wekvet6f	245	20	the	the	DT
cord-322516-wekvet6f	245	21	balance	balance	NN
cord-322516-wekvet6f	245	22	of	of	IN
cord-322516-wekvet6f	245	23	anterograde	anterograde	JJ
cord-322516-wekvet6f	245	24	and	and	CC
cord-322516-wekvet6f	245	25	retrograde	retrograde	JJ
cord-322516-wekvet6f	245	26	traffic	traffic	NN
cord-322516-wekvet6f	245	27	rates	rate	NNS
cord-322516-wekvet6f	245	28	.	.	.
cord-322516-wekvet6f	246	1	As	as	IN
cord-322516-wekvet6f	246	2	PDMP	PDMP	NNP
cord-322516-wekvet6f	246	3	slows	slow	VBZ
cord-322516-wekvet6f	246	4	anterograde	anterograde	JJ
cord-322516-wekvet6f	246	5	traffic	traffic	NN
cord-322516-wekvet6f	246	6	,	,	,
cord-322516-wekvet6f	246	7	IBV	IBV	NNP
cord-322516-wekvet6f	246	8	M	M	NNP
cord-322516-wekvet6f	246	9	could	could	MD
cord-322516-wekvet6f	246	10	accumulate	accumulate	VB
cord-322516-wekvet6f	246	11	in	in	IN
cord-322516-wekvet6f	246	12	the	the	DT
cord-322516-wekvet6f	246	13	ER	er	NN
cord-322516-wekvet6f	246	14	when	when	WRB
cord-322516-wekvet6f	246	15	the	the	DT
cord-322516-wekvet6f	246	16	balance	balance	NN
cord-322516-wekvet6f	246	17	of	of	IN
cord-322516-wekvet6f	246	18	membrane	membrane	NN
cord-322516-wekvet6f	246	19	traffic	traffic	NN
cord-322516-wekvet6f	246	20	is	be	VBZ
cord-322516-wekvet6f	246	21	disrupted	disrupt	VBN
cord-322516-wekvet6f	246	22	(	(	-LRB-
cord-322516-wekvet6f	246	23	left	leave	VBN
cord-322516-wekvet6f	246	24	arrow	arrow	NN
cord-322516-wekvet6f	246	25	)	)	-RRB-
cord-322516-wekvet6f	246	26	.	.	.
cord-322516-wekvet6f	247	1	Alternatively	alternatively	RB
cord-322516-wekvet6f	247	2	,	,	,
cord-322516-wekvet6f	247	3	PDMP	PDMP	NNP
cord-322516-wekvet6f	247	4	may	may	MD
cord-322516-wekvet6f	247	5	act	act	VB
cord-322516-wekvet6f	247	6	by	by	IN
cord-322516-wekvet6f	247	7	disrupting	disrupt	VBG
cord-322516-wekvet6f	247	8	the	the	DT
cord-322516-wekvet6f	247	9	retention	retention	NN
cord-322516-wekvet6f	247	10	of	of	IN
cord-322516-wekvet6f	247	11	IBV	IBV	NNP
cord-322516-wekvet6f	247	12	M	M	NNP
cord-322516-wekvet6f	247	13	,	,	,
cord-322516-wekvet6f	247	14	causing	cause	VBG
cord-322516-wekvet6f	247	15	it	-PRON-	PRP
cord-322516-wekvet6f	247	16	to	to	TO
cord-322516-wekvet6f	247	17	move	move	VB
cord-322516-wekvet6f	247	18	out	out	IN
cord-322516-wekvet6f	247	19	of	of	IN
cord-322516-wekvet6f	247	20	the	the	DT
cord-322516-wekvet6f	247	21	Golgi	Golgi	NNP
cord-322516-wekvet6f	247	22	(	(	-LRB-
cord-322516-wekvet6f	247	23	right	right	JJ
cord-322516-wekvet6f	247	24	arrow	arrow	NN
cord-322516-wekvet6f	247	25	)	)	-RRB-
cord-322516-wekvet6f	247	26	.	.	.
cord-322516-wekvet6f	248	1	It	-PRON-	PRP
cord-322516-wekvet6f	248	2	is	be	VBZ
cord-322516-wekvet6f	248	3	also	also	RB
cord-322516-wekvet6f	248	4	possible	possible	JJ
cord-322516-wekvet6f	248	5	that	that	IN
cord-322516-wekvet6f	248	6	redistribution	redistribution	NN
cord-322516-wekvet6f	248	7	of	of	IN
cord-322516-wekvet6f	248	8	IBV	IBV	NNP
cord-322516-wekvet6f	248	9	M	M	NNP
cord-322516-wekvet6f	248	10	requires	require	VBZ
cord-322516-wekvet6f	248	11	both	both	DT
cord-322516-wekvet6f	248	12	effects	effect	NNS
cord-322516-wekvet6f	248	13	of	of	IN
cord-322516-wekvet6f	248	14	PDMP	PDMP	NNP
cord-322516-wekvet6f	248	15	.	.	.
cord-322516-wekvet6f	249	1	staining	stain	VBG
cord-322516-wekvet6f	249	2	pattern	pattern	NN
cord-322516-wekvet6f	249	3	of	of	IN
cord-322516-wekvet6f	249	4	IBV	IBV	NNP
cord-322516-wekvet6f	249	5	M	M	NNP
cord-322516-wekvet6f	249	6	,	,	,
cord-322516-wekvet6f	249	7	we	-PRON-	PRP
cord-322516-wekvet6f	249	8	did	do	VBD
cord-322516-wekvet6f	249	9	detect	detect	VB
cord-322516-wekvet6f	249	10	a	a	DT
cord-322516-wekvet6f	249	11	slight	slight	JJ
cord-322516-wekvet6f	249	12	shift	shift	NN
cord-322516-wekvet6f	249	13	toward	toward	IN
cord-322516-wekvet6f	249	14	the	the	DT
cord-322516-wekvet6f	249	15	intermediate	intermediate	JJ
cord-322516-wekvet6f	249	16	staining	staining	NN
cord-322516-wekvet6f	249	17	pattern	pattern	NN
cord-322516-wekvet6f	249	18	(	(	-LRB-
cord-322516-wekvet6f	249	19	Fig	Fig	NNP
cord-322516-wekvet6f	249	20	.	.	NNP
cord-322516-wekvet6f	249	21	7	7	CD
cord-322516-wekvet6f	249	22	)	)	-RRB-
cord-322516-wekvet6f	249	23	.	.	.
cord-322516-wekvet6f	250	1	Whether	whether	IN
cord-322516-wekvet6f	250	2	this	this	DT
cord-322516-wekvet6f	250	3	represents	represent	VBZ
cord-322516-wekvet6f	250	4	an	an	DT
cord-322516-wekvet6f	250	5	altered	altered	JJ
cord-322516-wekvet6f	250	6	distribution	distribution	NN
cord-322516-wekvet6f	250	7	pattern	pattern	NN
cord-322516-wekvet6f	250	8	or	or	CC
cord-322516-wekvet6f	250	9	subtle	subtle	JJ
cord-322516-wekvet6f	250	10	effects	effect	NNS
cord-322516-wekvet6f	250	11	on	on	IN
cord-322516-wekvet6f	250	12	Golgi	Golgi	NNP
cord-322516-wekvet6f	250	13	structure	structure	NN
cord-322516-wekvet6f	250	14	caused	cause	VBN
cord-322516-wekvet6f	250	15	by	by	IN
cord-322516-wekvet6f	250	16	these	these	DT
cord-322516-wekvet6f	250	17	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	250	18	is	be	VBZ
cord-322516-wekvet6f	250	19	unclear	unclear	JJ
cord-322516-wekvet6f	250	20	.	.	.
cord-322516-wekvet6f	251	1	From	from	IN
cord-322516-wekvet6f	251	2	these	these	DT
cord-322516-wekvet6f	251	3	results	result	NNS
cord-322516-wekvet6f	251	4	we	-PRON-	PRP
cord-322516-wekvet6f	251	5	conclude	conclude	VBP
cord-322516-wekvet6f	251	6	that	that	IN
cord-322516-wekvet6f	251	7	ongoing	ongoing	JJ
cord-322516-wekvet6f	251	8	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	251	9	synthesis	synthesis	NN
cord-322516-wekvet6f	251	10	is	be	VBZ
cord-322516-wekvet6f	251	11	not	not	RB
cord-322516-wekvet6f	251	12	required	require	VBN
cord-322516-wekvet6f	251	13	for	for	IN
cord-322516-wekvet6f	251	14	either	either	DT
cord-322516-wekvet6f	251	15	normal	normal	JJ
cord-322516-wekvet6f	251	16	rates	rate	NNS
cord-322516-wekvet6f	251	17	of	of	IN
cord-322516-wekvet6f	251	18	anterograde	anterograde	JJ
cord-322516-wekvet6f	251	19	traffic	traffic	NN
cord-322516-wekvet6f	251	20	or	or	CC
cord-322516-wekvet6f	251	21	proper	proper	JJ
cord-322516-wekvet6f	251	22	localization	localization	NN
cord-322516-wekvet6f	251	23	of	of	IN
cord-322516-wekvet6f	251	24	Golgi	Golgi	NNP
cord-322516-wekvet6f	251	25	proteins	protein	NNS
cord-322516-wekvet6f	251	26	.	.	.
cord-322516-wekvet6f	252	1	However	however	RB
cord-322516-wekvet6f	252	2	,	,	,
cord-322516-wekvet6f	252	3	the	the	DT
cord-322516-wekvet6f	252	4	glucosylceramide	glucosylceramide	NN
cord-322516-wekvet6f	252	5	analogue	analogue	NN
cord-322516-wekvet6f	252	6	PDMP	PDMP	NNP
cord-322516-wekvet6f	252	7	,	,	,
cord-322516-wekvet6f	252	8	at	at	IN
cord-322516-wekvet6f	252	9	a	a	DT
cord-322516-wekvet6f	252	10	concentration	concentration	NN
cord-322516-wekvet6f	252	11	that	that	WDT
cord-322516-wekvet6f	252	12	inhibits	inhibit	VBZ
cord-322516-wekvet6f	252	13	both	both	DT
cord-322516-wekvet6f	252	14	GlcCer	GlcCer	NNP
cord-322516-wekvet6f	252	15	and	and	CC
cord-322516-wekvet6f	252	16	SM	SM	NNP
cord-322516-wekvet6f	252	17	synthases	synthase	NNS
cord-322516-wekvet6f	252	18	,	,	,
cord-322516-wekvet6f	252	19	causes	cause	VBZ
cord-322516-wekvet6f	252	20	a	a	DT
cord-322516-wekvet6f	252	21	redistribution	redistribution	NN
cord-322516-wekvet6f	252	22	of	of	IN
cord-322516-wekvet6f	252	23	IBV	IBV	NNP
cord-322516-wekvet6f	252	24	M	M	NNP
cord-322516-wekvet6f	252	25	to	to	IN
cord-322516-wekvet6f	252	26	the	the	DT
cord-322516-wekvet6f	252	27	ER	er	NN
cord-322516-wekvet6f	252	28	and	and	CC
cord-322516-wekvet6f	252	29	a	a	DT
cord-322516-wekvet6f	252	30	slowing	slowing	NN
cord-322516-wekvet6f	252	31	of	of	IN
cord-322516-wekvet6f	252	32	anterograde	anterograde	JJ
cord-322516-wekvet6f	252	33	traffic	traffic	NN
cord-322516-wekvet6f	252	34	in	in	IN
cord-322516-wekvet6f	252	35	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	252	36	cells	cell	NNS
cord-322516-wekvet6f	252	37	.	.	.
cord-322516-wekvet6f	253	1	Why	why	WRB
cord-322516-wekvet6f	253	2	does	do	VBZ
cord-322516-wekvet6f	253	3	PDMP	PDMP	NNP
cord-322516-wekvet6f	253	4	have	have	VB
cord-322516-wekvet6f	253	5	these	these	DT
cord-322516-wekvet6f	253	6	effects	effect	NNS
cord-322516-wekvet6f	253	7	while	while	IN
cord-322516-wekvet6f	253	8	␤	␤	.
cord-322516-wekvet6f	254	1	CA	CA	NNP
cord-322516-wekvet6f	254	2	and	and	CC
cord-322516-wekvet6f	254	3	FB1	FB1	NNP
cord-322516-wekvet6f	254	4	do	do	VB
cord-322516-wekvet6f	254	5	not	not	RB
cord-322516-wekvet6f	254	6	?	?	.
cord-322516-wekvet6f	255	1	It	-PRON-	PRP
cord-322516-wekvet6f	255	2	is	be	VBZ
cord-322516-wekvet6f	255	3	likely	likely	JJ
cord-322516-wekvet6f	255	4	that	that	IN
cord-322516-wekvet6f	255	5	PDMP	PDMP	NNP
cord-322516-wekvet6f	255	6	exerts	exert	VBZ
cord-322516-wekvet6f	255	7	its	-PRON-	PRP$
cord-322516-wekvet6f	255	8	effects	effect	NNS
cord-322516-wekvet6f	255	9	by	by	IN
cord-322516-wekvet6f	255	10	causing	cause	VBG
cord-322516-wekvet6f	255	11	the	the	DT
cord-322516-wekvet6f	255	12	accumulation	accumulation	NN
cord-322516-wekvet6f	255	13	of	of	IN
cord-322516-wekvet6f	255	14	ceramide	ceramide	NN
cord-322516-wekvet6f	255	15	.	.	.
cord-322516-wekvet6f	256	1	Other	other	JJ
cord-322516-wekvet6f	256	2	groups	group	NNS
cord-322516-wekvet6f	256	3	have	have	VBP
cord-322516-wekvet6f	256	4	found	find	VBN
cord-322516-wekvet6f	256	5	that	that	IN
cord-322516-wekvet6f	256	6	the	the	DT
cord-322516-wekvet6f	256	7	various	various	JJ
cord-322516-wekvet6f	256	8	effects	effect	NNS
cord-322516-wekvet6f	256	9	of	of	IN
cord-322516-wekvet6f	256	10	PDMP	PDMP	NNP
cord-322516-wekvet6f	256	11	and	and	CC
cord-322516-wekvet6f	256	12	its	-PRON-	PRP$
cord-322516-wekvet6f	256	13	active	active	JJ
cord-322516-wekvet6f	256	14	analogues	analogue	NNS
cord-322516-wekvet6f	256	15	were	be	VBD
cord-322516-wekvet6f	256	16	concomitant	concomitant	JJ
cord-322516-wekvet6f	256	17	with	with	IN
cord-322516-wekvet6f	256	18	(	(	-LRB-
cord-322516-wekvet6f	256	19	Uemura	Uemura	NNP
cord-322516-wekvet6f	256	20	et	et	NNP
cord-322516-wekvet6f	256	21	al	al	NNP
cord-322516-wekvet6f	256	22	.	.	NNP
cord-322516-wekvet6f	256	23	,	,	,
cord-322516-wekvet6f	256	24	1990	1990	CD
cord-322516-wekvet6f	256	25	;	;	:
cord-322516-wekvet6f	256	26	Shayman	Shayman	NNP
cord-322516-wekvet6f	256	27	et	et	NNP
cord-322516-wekvet6f	256	28	al	al	NNP
cord-322516-wekvet6f	256	29	.	.	NNP
cord-322516-wekvet6f	256	30	;	;	:
cord-322516-wekvet6f	257	1	Rani	Rani	NNP
cord-322516-wekvet6f	257	2	et	et	NNP
cord-322516-wekvet6f	257	3	al	al	NNP
cord-322516-wekvet6f	257	4	.	.	NNP
cord-322516-wekvet6f	257	5	,	,	,
cord-322516-wekvet6f	257	6	1995	1995	CD
cord-322516-wekvet6f	257	7	)	)	-RRB-
cord-322516-wekvet6f	257	8	or	or	CC
cord-322516-wekvet6f	257	9	actually	actually	RB
cord-322516-wekvet6f	257	10	caused	cause	VBN
cord-322516-wekvet6f	257	11	by	by	IN
cord-322516-wekvet6f	257	12	increases	increase	NNS
cord-322516-wekvet6f	257	13	in	in	IN
cord-322516-wekvet6f	257	14	ceramide	ceramide	NN
cord-322516-wekvet6f	257	15	concentrations	concentration	NNS
cord-322516-wekvet6f	257	16	(	(	-LRB-
cord-322516-wekvet6f	258	1	Abe	Abe	NNP
cord-322516-wekvet6f	258	2	et	et	NNP
cord-322516-wekvet6f	258	3	al	al	NNP
cord-322516-wekvet6f	258	4	.	.	.
cord-322516-wekvet6f	259	1	,	,	,
cord-322516-wekvet6f	259	2	1996	1996	CD
cord-322516-wekvet6f	259	3	;	;	:
cord-322516-wekvet6f	259	4	Posse	Posse	NNP
cord-322516-wekvet6f	259	5	de	de	FW
cord-322516-wekvet6f	259	6	Chaves	Chaves	NNP
cord-322516-wekvet6f	260	1	et	et	NNP
cord-322516-wekvet6f	260	2	al	al	NNP
cord-322516-wekvet6f	260	3	.	.	NNP
cord-322516-wekvet6f	260	4	,	,	,
cord-322516-wekvet6f	260	5	1997	1997	CD
cord-322516-wekvet6f	260	6	)	)	-RRB-
cord-322516-wekvet6f	260	7	.	.	.
cord-322516-wekvet6f	261	1	In	in	IN
cord-322516-wekvet6f	261	2	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	261	3	cells	cell	NNS
cord-322516-wekvet6f	261	4	treated	treat	VBN
cord-322516-wekvet6f	261	5	with	with	IN
cord-322516-wekvet6f	261	6	100	100	CD
cord-322516-wekvet6f	261	7	M	M	NNP
cord-322516-wekvet6f	261	8	PDMP	PDMP	NNP
cord-322516-wekvet6f	261	9	for	for	IN
cord-322516-wekvet6f	261	10	1	1	CD
cord-322516-wekvet6f	261	11	h	h	NN
cord-322516-wekvet6f	262	1	we	-PRON-	PRP
cord-322516-wekvet6f	262	2	measured	measure	VBD
cord-322516-wekvet6f	262	3	an	an	DT
cord-322516-wekvet6f	262	4	increase	increase	NN
cord-322516-wekvet6f	262	5	in	in	IN
cord-322516-wekvet6f	262	6	newly	newly	RB
cord-322516-wekvet6f	262	7	synthesized	synthesize	VBN
cord-322516-wekvet6f	262	8	ceramide	ceramide	NN
cord-322516-wekvet6f	262	9	(	(	-LRB-
cord-322516-wekvet6f	262	10	Fig	Fig	NNP
cord-322516-wekvet6f	262	11	.	.	.
cord-322516-wekvet6f	262	12	8	8	CD
cord-322516-wekvet6f	262	13	A	a	CD
cord-322516-wekvet6f	262	14	)	)	-RRB-
cord-322516-wekvet6f	262	15	,	,	,
cord-322516-wekvet6f	262	16	showing	show	VBG
cord-322516-wekvet6f	262	17	at	at	IN
cord-322516-wekvet6f	262	18	least	least	JJS
cord-322516-wekvet6f	262	19	a	a	DT
cord-322516-wekvet6f	262	20	correlation	correlation	NN
cord-322516-wekvet6f	262	21	between	between	IN
cord-322516-wekvet6f	262	22	levels	level	NNS
cord-322516-wekvet6f	262	23	of	of	IN
cord-322516-wekvet6f	262	24	newly	newly	RB
cord-322516-wekvet6f	262	25	synthesized	synthesize	VBN
cord-322516-wekvet6f	262	26	ceramide	ceramide	NN
cord-322516-wekvet6f	262	27	and	and	CC
cord-322516-wekvet6f	262	28	the	the	DT
cord-322516-wekvet6f	262	29	effects	effect	NNS
cord-322516-wekvet6f	262	30	of	of	IN
cord-322516-wekvet6f	262	31	PDMP	PDMP	NNP
cord-322516-wekvet6f	262	32	on	on	IN
cord-322516-wekvet6f	262	33	protein	protein	NN
cord-322516-wekvet6f	262	34	traffic	traffic	NN
cord-322516-wekvet6f	262	35	and	and	CC
cord-322516-wekvet6f	262	36	localization	localization	NN
cord-322516-wekvet6f	262	37	.	.	.
cord-322516-wekvet6f	263	1	The	the	DT
cord-322516-wekvet6f	263	2	fact	fact	NN
cord-322516-wekvet6f	263	3	that	that	IN
cord-322516-wekvet6f	263	4	pretreatment	pretreatment	NN
cord-322516-wekvet6f	263	5	with	with	IN
cord-322516-wekvet6f	263	6	either	either	CC
cord-322516-wekvet6f	263	7	␤	␤	NNP
cord-322516-wekvet6f	263	8	CA	CA	NNP
cord-322516-wekvet6f	263	9	or	or	CC
cord-322516-wekvet6f	263	10	FB1	FB1	NNP
cord-322516-wekvet6f	263	11	,	,	,
cord-322516-wekvet6f	263	12	both	both	DT
cord-322516-wekvet6f	263	13	of	of	IN
cord-322516-wekvet6f	263	14	which	which	WDT
cord-322516-wekvet6f	263	15	block	block	VBP
cord-322516-wekvet6f	263	16	the	the	DT
cord-322516-wekvet6f	263	17	synthesis	synthesis	NN
cord-322516-wekvet6f	263	18	of	of	IN
cord-322516-wekvet6f	263	19	ceramide	ceramide	NN
cord-322516-wekvet6f	263	20	,	,	,
cord-322516-wekvet6f	263	21	can	can	MD
cord-322516-wekvet6f	263	22	ameliorate	ameliorate	VB
cord-322516-wekvet6f	263	23	the	the	DT
cord-322516-wekvet6f	263	24	effects	effect	NNS
cord-322516-wekvet6f	263	25	of	of	IN
cord-322516-wekvet6f	263	26	PDMP	PDMP	NNP
cord-322516-wekvet6f	263	27	demonstrates	demonstrate	VBZ
cord-322516-wekvet6f	263	28	that	that	IN
cord-322516-wekvet6f	263	29	ceramide	ceramide	NN
cord-322516-wekvet6f	263	30	is	be	VBZ
cord-322516-wekvet6f	263	31	at	at	IN
cord-322516-wekvet6f	263	32	least	least	JJS
cord-322516-wekvet6f	263	33	in	in	IN
cord-322516-wekvet6f	263	34	part	part	NN
cord-322516-wekvet6f	263	35	the	the	DT
cord-322516-wekvet6f	263	36	mediator	mediator	NN
cord-322516-wekvet6f	263	37	of	of	IN
cord-322516-wekvet6f	263	38	these	these	DT
cord-322516-wekvet6f	263	39	effects	effect	NNS
cord-322516-wekvet6f	263	40	.	.	.
cord-322516-wekvet6f	264	1	However	however	RB
cord-322516-wekvet6f	264	2	,	,	,
cord-322516-wekvet6f	264	3	the	the	DT
cord-322516-wekvet6f	264	4	effects	effect	NNS
cord-322516-wekvet6f	264	5	of	of	IN
cord-322516-wekvet6f	264	6	PDMP	PDMP	NNP
cord-322516-wekvet6f	264	7	are	be	VBP
cord-322516-wekvet6f	264	8	not	not	RB
cord-322516-wekvet6f	264	9	completely	completely	RB
cord-322516-wekvet6f	264	10	abolished	abolish	VBN
cord-322516-wekvet6f	264	11	by	by	IN
cord-322516-wekvet6f	264	12	pretreatment	pretreatment	NN
cord-322516-wekvet6f	264	13	,	,	,
cord-322516-wekvet6f	264	14	even	even	RB
cord-322516-wekvet6f	264	15	though	though	IN
cord-322516-wekvet6f	264	16	␤	␤	NNP
cord-322516-wekvet6f	264	17	CA	CA	NNP
cord-322516-wekvet6f	264	18	pretreatment	pretreatment	NN
cord-322516-wekvet6f	264	19	reduced	reduce	VBD
cord-322516-wekvet6f	264	20	the	the	DT
cord-322516-wekvet6f	264	21	level	level	NN
cord-322516-wekvet6f	264	22	of	of	IN
cord-322516-wekvet6f	264	23	newly	newly	RB
cord-322516-wekvet6f	264	24	synthesized	synthesize	VBN
cord-322516-wekvet6f	264	25	ceramide	ceramide	NN
cord-322516-wekvet6f	264	26	by	by	IN
cord-322516-wekvet6f	264	27	50	50	CD
cord-322516-wekvet6f	264	28	%	%	NN
cord-322516-wekvet6f	264	29	compared	compare	VBN
cord-322516-wekvet6f	264	30	to	to	IN
cord-322516-wekvet6f	264	31	control	control	NN
cord-322516-wekvet6f	264	32	.	.	.
cord-322516-wekvet6f	265	1	One	one	CD
cord-322516-wekvet6f	265	2	explanation	explanation	NN
cord-322516-wekvet6f	265	3	is	be	VBZ
cord-322516-wekvet6f	265	4	that	that	IN
cord-322516-wekvet6f	265	5	ceramide	ceramide	NN
cord-322516-wekvet6f	265	6	accumulation	accumulation	NN
cord-322516-wekvet6f	265	7	is	be	VBZ
cord-322516-wekvet6f	265	8	only	only	RB
cord-322516-wekvet6f	265	9	one	one	CD
cord-322516-wekvet6f	265	10	of	of	IN
cord-322516-wekvet6f	265	11	the	the	DT
cord-322516-wekvet6f	265	12	ways	way	NNS
cord-322516-wekvet6f	265	13	that	that	WDT
cord-322516-wekvet6f	265	14	PDMP	PDMP	NNP
cord-322516-wekvet6f	265	15	exerts	exert	VBZ
cord-322516-wekvet6f	265	16	its	-PRON-	PRP$
cord-322516-wekvet6f	265	17	effects	effect	NNS
cord-322516-wekvet6f	265	18	.	.	.
cord-322516-wekvet6f	266	1	Another	another	DT
cord-322516-wekvet6f	266	2	possibility	possibility	NN
cord-322516-wekvet6f	266	3	is	be	VBZ
cord-322516-wekvet6f	266	4	that	that	DT
cord-322516-wekvet6f	266	5	ceramide	ceramide	NN
cord-322516-wekvet6f	266	6	is	be	VBZ
cord-322516-wekvet6f	266	7	being	be	VBG
cord-322516-wekvet6f	266	8	generated	generate	VBN
cord-322516-wekvet6f	266	9	by	by	IN
cord-322516-wekvet6f	266	10	the	the	DT
cord-322516-wekvet6f	266	11	degradation	degradation	NN
cord-322516-wekvet6f	266	12	of	of	IN
cord-322516-wekvet6f	266	13	preexisting	preexisting	JJ
cord-322516-wekvet6f	266	14	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	266	15	,	,	,
cord-322516-wekvet6f	266	16	e.g.	e.g.	RB
cord-322516-wekvet6f	266	17	,	,	,
cord-322516-wekvet6f	266	18	at	at	IN
cord-322516-wekvet6f	266	19	the	the	DT
cord-322516-wekvet6f	266	20	cell	cell	NN
cord-322516-wekvet6f	266	21	surface	surface	NN
cord-322516-wekvet6f	266	22	or	or	CC
cord-322516-wekvet6f	266	23	in	in	IN
cord-322516-wekvet6f	266	24	lysosomes	lysosome	NNS
cord-322516-wekvet6f	266	25	.	.	.
cord-322516-wekvet6f	267	1	This	this	DT
cord-322516-wekvet6f	267	2	ceramide	ceramide	NN
cord-322516-wekvet6f	267	3	can	can	MD
cord-322516-wekvet6f	267	4	not	not	RB
cord-322516-wekvet6f	267	5	be	be	VB
cord-322516-wekvet6f	267	6	made	make	VBN
cord-322516-wekvet6f	267	7	back	back	RP
cord-322516-wekvet6f	267	8	into	into	IN
cord-322516-wekvet6f	267	9	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	267	10	because	because	IN
cord-322516-wekvet6f	267	11	the	the	DT
cord-322516-wekvet6f	267	12	enzymes	enzyme	NNS
cord-322516-wekvet6f	267	13	SM	SM	NNP
cord-322516-wekvet6f	267	14	and	and	CC
cord-322516-wekvet6f	267	15	GlcCer	GlcCer	NNP
cord-322516-wekvet6f	267	16	synthases	synthase	NNS
cord-322516-wekvet6f	267	17	are	be	VBP
cord-322516-wekvet6f	267	18	inhibited	inhibit	VBN
cord-322516-wekvet6f	267	19	in	in	IN
cord-322516-wekvet6f	267	20	the	the	DT
cord-322516-wekvet6f	267	21	presence	presence	NN
cord-322516-wekvet6f	267	22	of	of	IN
cord-322516-wekvet6f	267	23	PDMP	PDMP	NNP
cord-322516-wekvet6f	267	24	.	.	.
cord-322516-wekvet6f	268	1	Interestingly	interestingly	RB
cord-322516-wekvet6f	268	2	,	,	,
cord-322516-wekvet6f	268	3	the	the	DT
cord-322516-wekvet6f	268	4	fluorograph	fluorograph	NN
cord-322516-wekvet6f	268	5	of	of	IN
cord-322516-wekvet6f	268	6	the	the	DT
cord-322516-wekvet6f	268	7	ceramide	ceramide	NN
cord-322516-wekvet6f	268	8	bands	band	NNS
cord-322516-wekvet6f	268	9	generated	generate	VBN
cord-322516-wekvet6f	268	10	after	after	IN
cord-322516-wekvet6f	268	11	the	the	DT
cord-322516-wekvet6f	268	12	various	various	JJ
cord-322516-wekvet6f	268	13	treatments	treatment	NNS
cord-322516-wekvet6f	268	14	(	(	-LRB-
cord-322516-wekvet6f	268	15	Fig	Fig	NNP
cord-322516-wekvet6f	268	16	.	.	.
cord-322516-wekvet6f	268	17	8	8	CD
cord-322516-wekvet6f	268	18	 	 	_SP
cord-322516-wekvet6f	268	19	B	b	NN
cord-322516-wekvet6f	268	20	)	)	-RRB-
cord-322516-wekvet6f	268	21	shows	show	VBZ
cord-322516-wekvet6f	268	22	different	different	JJ
cord-322516-wekvet6f	268	23	relative	relative	JJ
cord-322516-wekvet6f	268	24	amounts	amount	NNS
cord-322516-wekvet6f	268	25	of	of	IN
cord-322516-wekvet6f	268	26	ceramide	ceramide	NN
cord-322516-wekvet6f	268	27	species	specie	NNS
cord-322516-wekvet6f	268	28	.	.	.
cord-322516-wekvet6f	269	1	We	-PRON-	PRP
cord-322516-wekvet6f	269	2	suspect	suspect	VBP
cord-322516-wekvet6f	269	3	that	that	IN
cord-322516-wekvet6f	269	4	these	these	DT
cord-322516-wekvet6f	269	5	ceramides	ceramide	NNS
cord-322516-wekvet6f	269	6	differ	differ	VBP
cord-322516-wekvet6f	269	7	in	in	IN
cord-322516-wekvet6f	269	8	acyl	acyl	NN
cord-322516-wekvet6f	269	9	chain	chain	NN
cord-322516-wekvet6f	269	10	lengths	length	NNS
cord-322516-wekvet6f	269	11	(	(	-LRB-
cord-322516-wekvet6f	269	12	Abe	Abe	NNP
cord-322516-wekvet6f	269	13	et	et	NNP
cord-322516-wekvet6f	269	14	al	al	NNP
cord-322516-wekvet6f	269	15	.	.	NNP
cord-322516-wekvet6f	269	16	,	,	,
cord-322516-wekvet6f	269	17	1992	1992	CD
cord-322516-wekvet6f	269	18	)	)	-RRB-
cord-322516-wekvet6f	269	19	and	and	CC
cord-322516-wekvet6f	269	20	that	that	IN
cord-322516-wekvet6f	269	21	this	this	DT
cord-322516-wekvet6f	269	22	may	may	MD
cord-322516-wekvet6f	269	23	be	be	VB
cord-322516-wekvet6f	269	24	an	an	DT
cord-322516-wekvet6f	269	25	indication	indication	NN
cord-322516-wekvet6f	269	26	of	of	IN
cord-322516-wekvet6f	269	27	different	different	JJ
cord-322516-wekvet6f	269	28	sources	source	NNS
cord-322516-wekvet6f	269	29	of	of	IN
cord-322516-wekvet6f	269	30	ceramide	ceramide	NN
cord-322516-wekvet6f	269	31	,	,	,
cord-322516-wekvet6f	269	32	i.e.	i.e.	FW
cord-322516-wekvet6f	269	33	,	,	,
cord-322516-wekvet6f	269	34	de	de	FW
cord-322516-wekvet6f	269	35	novo	novo	NNP
cord-322516-wekvet6f	269	36	synthesis	synthesis	NNP
cord-322516-wekvet6f	269	37	or	or	CC
cord-322516-wekvet6f	269	38	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	269	39	degradation	degradation	NN
cord-322516-wekvet6f	269	40	.	.	.
cord-322516-wekvet6f	270	1	We	-PRON-	PRP
cord-322516-wekvet6f	270	2	are	be	VBP
cord-322516-wekvet6f	270	3	currently	currently	RB
cord-322516-wekvet6f	270	4	investigating	investigate	VBG
cord-322516-wekvet6f	270	5	this	this	DT
cord-322516-wekvet6f	270	6	possibility	possibility	NN
cord-322516-wekvet6f	270	7	.	.	.
cord-322516-wekvet6f	271	1	Based	base	VBN
cord-322516-wekvet6f	271	2	on	on	IN
cord-322516-wekvet6f	271	3	the	the	DT
cord-322516-wekvet6f	271	4	pretreatment	pretreatment	NN
cord-322516-wekvet6f	271	5	results	result	NNS
cord-322516-wekvet6f	271	6	,	,	,
cord-322516-wekvet6f	271	7	we	-PRON-	PRP
cord-322516-wekvet6f	271	8	expected	expect	VBD
cord-322516-wekvet6f	271	9	that	that	IN
cord-322516-wekvet6f	271	10	soluble	soluble	JJ
cord-322516-wekvet6f	271	11	analogues	analogue	NNS
cord-322516-wekvet6f	271	12	of	of	IN
cord-322516-wekvet6f	271	13	ceramide	ceramide	NN
cord-322516-wekvet6f	271	14	would	would	MD
cord-322516-wekvet6f	271	15	mimic	mimic	VB
cord-322516-wekvet6f	271	16	the	the	DT
cord-322516-wekvet6f	271	17	effects	effect	NNS
cord-322516-wekvet6f	271	18	of	of	IN
cord-322516-wekvet6f	271	19	PDMP	PDMP	NNP
cord-322516-wekvet6f	271	20	.	.	.
cord-322516-wekvet6f	272	1	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	272	2	and	and	CC
cord-322516-wekvet6f	272	3	Pagano	Pagano	NNP
cord-322516-wekvet6f	272	4	(	(	-LRB-
cord-322516-wekvet6f	272	5	1993	1993	CD
cord-322516-wekvet6f	272	6	)	)	-RRB-
cord-322516-wekvet6f	272	7	showed	show	VBD
cord-322516-wekvet6f	272	8	that	that	IN
cord-322516-wekvet6f	272	9	like	like	UH
cord-322516-wekvet6f	272	10	100	100	CD
cord-322516-wekvet6f	272	11	M	M	NNP
cord-322516-wekvet6f	272	12	PDMP	PDMP	NNP
cord-322516-wekvet6f	272	13	,	,	,
cord-322516-wekvet6f	272	14	25	25	CD
cord-322516-wekvet6f	272	15	M	M	NNP
cord-322516-wekvet6f	272	16	C	C	NNP
cord-322516-wekvet6f	272	17	6	6	CD
cord-322516-wekvet6f	272	18	Cer	Cer	NNP
cord-322516-wekvet6f	272	19	decreased	decrease	VBD
cord-322516-wekvet6f	272	20	the	the	DT
cord-322516-wekvet6f	272	21	rate	rate	NN
cord-322516-wekvet6f	272	22	of	of	IN
cord-322516-wekvet6f	272	23	transit	transit	NN
cord-322516-wekvet6f	272	24	of	of	IN
cord-322516-wekvet6f	272	25	an	an	DT
cord-322516-wekvet6f	272	26	itinerant	itinerant	JJ
cord-322516-wekvet6f	272	27	protein	protein	NN
cord-322516-wekvet6f	272	28	to	to	IN
cord-322516-wekvet6f	272	29	the	the	DT
cord-322516-wekvet6f	272	30	medial	medial	JJ
cord-322516-wekvet6f	272	31	-	-	HYPH
cord-322516-wekvet6f	272	32	Golgi	Golgi	NNP
cord-322516-wekvet6f	272	33	in	in	IN
cord-322516-wekvet6f	272	34	CHO	CHO	NNP
cord-322516-wekvet6f	272	35	cells	cell	NNS
cord-322516-wekvet6f	272	36	.	.	.
cord-322516-wekvet6f	273	1	Consistent	consistent	JJ
cord-322516-wekvet6f	273	2	with	with	IN
cord-322516-wekvet6f	273	3	these	these	DT
cord-322516-wekvet6f	273	4	results	result	NNS
cord-322516-wekvet6f	273	5	,	,	,
cord-322516-wekvet6f	273	6	25	25	CD
cord-322516-wekvet6f	273	7	M	M	NNP
cord-322516-wekvet6f	273	8	C	C	NNP
cord-322516-wekvet6f	273	9	6	6	CD
cord-322516-wekvet6f	273	10	Cer	Cer	NNP
cord-322516-wekvet6f	273	11	also	also	RB
cord-322516-wekvet6f	273	12	slowed	slow	VBD
cord-322516-wekvet6f	273	13	anterograde	anterograde	JJ
cord-322516-wekvet6f	273	14	traffic	traffic	NN
cord-322516-wekvet6f	273	15	in	in	IN
cord-322516-wekvet6f	273	16	BHK-21	BHK-21	NNP
cord-322516-wekvet6f	273	17	cells	cell	NNS
cord-322516-wekvet6f	273	18	.	.	.
cord-322516-wekvet6f	274	1	However	however	RB
cord-322516-wekvet6f	274	2	,	,	,
cord-322516-wekvet6f	274	3	25	25	CD
cord-322516-wekvet6f	274	4	M	M	NNP
cord-322516-wekvet6f	274	5	C	C	NNP
cord-322516-wekvet6f	274	6	6	6	CD
cord-322516-wekvet6f	274	7	Cer	Cer	NNP
cord-322516-wekvet6f	274	8	had	have	VBD
cord-322516-wekvet6f	274	9	no	no	DT
cord-322516-wekvet6f	274	10	effect	effect	NN
cord-322516-wekvet6f	274	11	on	on	IN
cord-322516-wekvet6f	274	12	the	the	DT
cord-322516-wekvet6f	274	13	localization	localization	NN
cord-322516-wekvet6f	274	14	of	of	IN
cord-322516-wekvet6f	274	15	either	either	CC
cord-322516-wekvet6f	274	16	the	the	DT
cord-322516-wekvet6f	274	17	M	M	NNP
cord-322516-wekvet6f	274	18	protein	protein	NN
cord-322516-wekvet6f	274	19	or	or	CC
cord-322516-wekvet6f	274	20	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	274	21	.	.	.
cord-322516-wekvet6f	275	1	Other	other	JJ
cord-322516-wekvet6f	275	2	short	short	JJ
cord-322516-wekvet6f	275	3	-	-	HYPH
cord-322516-wekvet6f	275	4	chain	chain	NN
cord-322516-wekvet6f	275	5	ceramide	ceramide	NN
cord-322516-wekvet6f	275	6	analogues	analogue	NNS
cord-322516-wekvet6f	275	7	(	(	-LRB-
cord-322516-wekvet6f	275	8	C	C	NNP
cord-322516-wekvet6f	275	9	2and	2and	CD
cord-322516-wekvet6f	275	10	C	c	NN
cord-322516-wekvet6f	275	11	8	8	CD
cord-322516-wekvet6f	275	12	-ceramide	-ceramide	NN
cord-322516-wekvet6f	275	13	)	)	-RRB-
cord-322516-wekvet6f	275	14	also	also	RB
cord-322516-wekvet6f	275	15	had	have	VBD
cord-322516-wekvet6f	275	16	no	no	DT
cord-322516-wekvet6f	275	17	effect	effect	NN
cord-322516-wekvet6f	275	18	on	on	IN
cord-322516-wekvet6f	275	19	IBV	IBV	NNP
cord-322516-wekvet6f	275	20	M	M	NNP
cord-322516-wekvet6f	275	21	localization	localization	NN
cord-322516-wekvet6f	275	22	.	.	.
cord-322516-wekvet6f	276	1	How	how	WRB
cord-322516-wekvet6f	276	2	does	do	VBZ
cord-322516-wekvet6f	276	3	this	this	DT
cord-322516-wekvet6f	276	4	fit	fit	VB
cord-322516-wekvet6f	276	5	with	with	IN
cord-322516-wekvet6f	276	6	our	-PRON-	PRP$
cord-322516-wekvet6f	276	7	model	model	NN
cord-322516-wekvet6f	276	8	that	that	DT
cord-322516-wekvet6f	276	9	ceramide	ceramide	NN
cord-322516-wekvet6f	276	10	mediates	mediate	VBZ
cord-322516-wekvet6f	276	11	PDMP	pdmp	NN
cord-322516-wekvet6f	276	12	effects	effect	NNS
cord-322516-wekvet6f	276	13	?	?	.
cord-322516-wekvet6f	277	1	One	one	CD
cord-322516-wekvet6f	277	2	explanation	explanation	NN
cord-322516-wekvet6f	277	3	is	be	VBZ
cord-322516-wekvet6f	277	4	that	that	IN
cord-322516-wekvet6f	277	5	the	the	DT
cord-322516-wekvet6f	277	6	effect	effect	NN
cord-322516-wekvet6f	277	7	on	on	IN
cord-322516-wekvet6f	277	8	protein	protein	NN
cord-322516-wekvet6f	277	9	localization	localization	NN
cord-322516-wekvet6f	277	10	is	be	VBZ
cord-322516-wekvet6f	277	11	independent	independent	JJ
cord-322516-wekvet6f	277	12	of	of	IN
cord-322516-wekvet6f	277	13	the	the	DT
cord-322516-wekvet6f	277	14	effect	effect	NN
cord-322516-wekvet6f	277	15	on	on	IN
cord-322516-wekvet6f	277	16	antero	antero	NNP
cord-322516-wekvet6f	277	17	-	-	HYPH
cord-322516-wekvet6f	277	18	grade	grade	NN
cord-322516-wekvet6f	277	19	traffic	traffic	NN
cord-322516-wekvet6f	277	20	rates	rate	NNS
cord-322516-wekvet6f	277	21	.	.	.
cord-322516-wekvet6f	278	1	In	in	IN
cord-322516-wekvet6f	278	2	this	this	DT
cord-322516-wekvet6f	278	3	case	case	NN
cord-322516-wekvet6f	278	4	,	,	,
cord-322516-wekvet6f	278	5	it	-PRON-	PRP
cord-322516-wekvet6f	278	6	may	may	MD
cord-322516-wekvet6f	278	7	be	be	VB
cord-322516-wekvet6f	278	8	that	that	IN
cord-322516-wekvet6f	278	9	C	C	NNP
cord-322516-wekvet6f	278	10	6	6	CD
cord-322516-wekvet6f	278	11	Cer	cer	NN
cord-322516-wekvet6f	278	12	and	and	CC
cord-322516-wekvet6f	278	13	endogenous	endogenous	JJ
cord-322516-wekvet6f	278	14	ceramide	ceramide	NN
cord-322516-wekvet6f	278	15	have	have	VBP
cord-322516-wekvet6f	278	16	similar	similar	JJ
cord-322516-wekvet6f	278	17	ability	ability	NN
cord-322516-wekvet6f	278	18	to	to	TO
cord-322516-wekvet6f	278	19	bind	bind	VB
cord-322516-wekvet6f	278	20	and	and	CC
cord-322516-wekvet6f	278	21	affect	affect	VB
cord-322516-wekvet6f	278	22	proteins	protein	NNS
cord-322516-wekvet6f	278	23	that	that	WDT
cord-322516-wekvet6f	278	24	regulate	regulate	VBP
cord-322516-wekvet6f	278	25	anterograde	anterograde	JJ
cord-322516-wekvet6f	278	26	traffic	traffic	NN
cord-322516-wekvet6f	278	27	,	,	,
cord-322516-wekvet6f	278	28	but	but	CC
cord-322516-wekvet6f	278	29	C	C	NNP
cord-322516-wekvet6f	278	30	6	6	CD
cord-322516-wekvet6f	278	31	Cer	Cer	NNP
cord-322516-wekvet6f	278	32	is	be	VBZ
cord-322516-wekvet6f	278	33	unable	unable	JJ
cord-322516-wekvet6f	278	34	to	to	TO
cord-322516-wekvet6f	278	35	bind	bind	VB
cord-322516-wekvet6f	278	36	or	or	CC
cord-322516-wekvet6f	278	37	affect	affect	VB
cord-322516-wekvet6f	278	38	proteins	protein	NNS
cord-322516-wekvet6f	278	39	that	that	WDT
cord-322516-wekvet6f	278	40	regulate	regulate	VBP
cord-322516-wekvet6f	278	41	protein	protein	NN
cord-322516-wekvet6f	278	42	localization	localization	NN
cord-322516-wekvet6f	278	43	.	.	.
cord-322516-wekvet6f	279	1	It	-PRON-	PRP
cord-322516-wekvet6f	279	2	has	have	VBZ
cord-322516-wekvet6f	279	3	been	be	VBN
cord-322516-wekvet6f	279	4	shown	show	VBN
cord-322516-wekvet6f	279	5	that	that	IN
cord-322516-wekvet6f	279	6	some	some	DT
cord-322516-wekvet6f	279	7	short	short	JJ
cord-322516-wekvet6f	279	8	chain	chain	NN
cord-322516-wekvet6f	279	9	analogues	analogue	NNS
cord-322516-wekvet6f	279	10	of	of	IN
cord-322516-wekvet6f	279	11	ceramide	ceramide	NN
cord-322516-wekvet6f	279	12	do	do	VBP
cord-322516-wekvet6f	279	13	not	not	RB
cord-322516-wekvet6f	279	14	have	have	VB
cord-322516-wekvet6f	279	15	the	the	DT
cord-322516-wekvet6f	279	16	same	same	JJ
cord-322516-wekvet6f	279	17	effects	effect	NNS
cord-322516-wekvet6f	279	18	as	as	IN
cord-322516-wekvet6f	279	19	endogenous	endogenous	JJ
cord-322516-wekvet6f	279	20	ceramide	ceramide	NN
cord-322516-wekvet6f	279	21	(	(	-LRB-
cord-322516-wekvet6f	279	22	e.g.	e.g.	RB
cord-322516-wekvet6f	279	23	,	,	,
cord-322516-wekvet6f	279	24	Wolff	Wolff	NNP
cord-322516-wekvet6f	279	25	et	et	NNP
cord-322516-wekvet6f	279	26	al	al	NNP
cord-322516-wekvet6f	279	27	.	.	NNP
cord-322516-wekvet6f	279	28	,	,	,
cord-322516-wekvet6f	279	29	1994	1994	CD
cord-322516-wekvet6f	279	30	)	)	-RRB-
cord-322516-wekvet6f	279	31	.	.	.
cord-322516-wekvet6f	280	1	A	a	DT
cord-322516-wekvet6f	280	2	second	second	JJ
cord-322516-wekvet6f	280	3	possibility	possibility	NN
cord-322516-wekvet6f	280	4	is	be	VBZ
cord-322516-wekvet6f	280	5	that	that	IN
cord-322516-wekvet6f	280	6	effects	effect	NNS
cord-322516-wekvet6f	280	7	of	of	IN
cord-322516-wekvet6f	280	8	ceramide	ceramide	NN
cord-322516-wekvet6f	280	9	are	be	VBP
cord-322516-wekvet6f	280	10	limited	limit	VBN
cord-322516-wekvet6f	280	11	to	to	IN
cord-322516-wekvet6f	280	12	the	the	DT
cord-322516-wekvet6f	280	13	bilayers	bilayer	NNS
cord-322516-wekvet6f	280	14	in	in	IN
cord-322516-wekvet6f	280	15	which	which	WDT
cord-322516-wekvet6f	280	16	its	-PRON-	PRP$
cord-322516-wekvet6f	280	17	concentration	concentration	NN
cord-322516-wekvet6f	280	18	increases	increase	VBZ
cord-322516-wekvet6f	280	19	,	,	,
cord-322516-wekvet6f	280	20	and	and	CC
cord-322516-wekvet6f	280	21	the	the	DT
cord-322516-wekvet6f	280	22	difference	difference	NN
cord-322516-wekvet6f	280	23	seen	see	VBN
cord-322516-wekvet6f	280	24	between	between	IN
cord-322516-wekvet6f	280	25	endogenous	endogenous	JJ
cord-322516-wekvet6f	280	26	ceramide	ceramide	NN
cord-322516-wekvet6f	280	27	and	and	CC
cord-322516-wekvet6f	280	28	exogenous	exogenous	JJ
cord-322516-wekvet6f	280	29	C	C	NNP
cord-322516-wekvet6f	280	30	6	6	CD
cord-322516-wekvet6f	280	31	Cer	Cer	NNP
cord-322516-wekvet6f	280	32	is	be	VBZ
cord-322516-wekvet6f	280	33	due	due	JJ
cord-322516-wekvet6f	280	34	to	to	IN
cord-322516-wekvet6f	280	35	the	the	DT
cord-322516-wekvet6f	280	36	different	different	JJ
cord-322516-wekvet6f	280	37	intracellular	intracellular	JJ
cord-322516-wekvet6f	280	38	distribution	distribution	NN
cord-322516-wekvet6f	280	39	of	of	IN
cord-322516-wekvet6f	280	40	these	these	DT
cord-322516-wekvet6f	280	41	molecules	molecule	NNS
cord-322516-wekvet6f	280	42	.	.	.
cord-322516-wekvet6f	281	1	C	C	NNP
cord-322516-wekvet6f	281	2	6	6	CD
cord-322516-wekvet6f	281	3	Cer	Cer	NNP
cord-322516-wekvet6f	281	4	would	would	MD
cord-322516-wekvet6f	281	5	be	be	VB
cord-322516-wekvet6f	281	6	unlikely	unlikely	JJ
cord-322516-wekvet6f	281	7	to	to	TO
cord-322516-wekvet6f	281	8	accumulate	accumulate	VB
cord-322516-wekvet6f	281	9	in	in	IN
cord-322516-wekvet6f	281	10	compartments	compartment	NNS
cord-322516-wekvet6f	281	11	where	where	WRB
cord-322516-wekvet6f	281	12	IBV	IBV	NNP
cord-322516-wekvet6f	281	13	M	M	NNP
cord-322516-wekvet6f	281	14	and	and	CC
cord-322516-wekvet6f	281	15	ERGIC	ERGIC	NNP
cord-322516-wekvet6f	281	16	53	53	CD
cord-322516-wekvet6f	281	17	reside	reside	VBP
cord-322516-wekvet6f	281	18	,	,	,
cord-322516-wekvet6f	281	19	because	because	IN
cord-322516-wekvet6f	281	20	it	-PRON-	PRP
cord-322516-wekvet6f	281	21	is	be	VBZ
cord-322516-wekvet6f	281	22	rapidly	rapidly	RB
cord-322516-wekvet6f	281	23	converted	convert	VBN
cord-322516-wekvet6f	281	24	to	to	IN
cord-322516-wekvet6f	281	25	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	281	26	there	there	RB
cord-322516-wekvet6f	282	1	(	(	-LRB-
cord-322516-wekvet6f	282	2	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	282	3	et	et	NNP
cord-322516-wekvet6f	282	4	al	al	NNP
cord-322516-wekvet6f	282	5	.	.	NNP
cord-322516-wekvet6f	282	6	,	,	,
cord-322516-wekvet6f	282	7	1992	1992	CD
cord-322516-wekvet6f	282	8	)	)	-RRB-
cord-322516-wekvet6f	282	9	.	.	.
cord-322516-wekvet6f	283	1	Effects	effect	NNS
cord-322516-wekvet6f	283	2	on	on	IN
cord-322516-wekvet6f	283	3	membrane	membrane	NN
cord-322516-wekvet6f	283	4	traffic	traffic	NN
cord-322516-wekvet6f	283	5	might	may	MD
cord-322516-wekvet6f	283	6	be	be	VB
cord-322516-wekvet6f	283	7	more	more	RBR
cord-322516-wekvet6f	283	8	dramatic	dramatic	JJ
cord-322516-wekvet6f	283	9	in	in	IN
cord-322516-wekvet6f	283	10	compartments	compartment	NNS
cord-322516-wekvet6f	283	11	where	where	WRB
cord-322516-wekvet6f	283	12	C	C	NNP
cord-322516-wekvet6f	283	13	6	6	CD
cord-322516-wekvet6f	283	14	Cer	cer	NN
cord-322516-wekvet6f	283	15	accumulates	accumulate	VBZ
cord-322516-wekvet6f	283	16	,	,	,
cord-322516-wekvet6f	283	17	possibly	possibly	RB
cord-322516-wekvet6f	283	18	the	the	DT
cord-322516-wekvet6f	283	19	trans	trans	NNP
cord-322516-wekvet6f	283	20	-	-	NNP
cord-322516-wekvet6f	283	21	Golgi	Golgi	NNP
cord-322516-wekvet6f	283	22	and	and	CC
cord-322516-wekvet6f	283	23	TGN	TGN	NNP
cord-322516-wekvet6f	283	24	(	(	-LRB-
cord-322516-wekvet6f	283	25	Pagano	Pagano	NNP
cord-322516-wekvet6f	283	26	et	et	NNP
cord-322516-wekvet6f	283	27	al	al	NNP
cord-322516-wekvet6f	283	28	.	.	NNP
cord-322516-wekvet6f	283	29	,	,	,
cord-322516-wekvet6f	283	30	1989	1989	CD
cord-322516-wekvet6f	283	31	)	)	-RRB-
cord-322516-wekvet6f	283	32	.	.	.
cord-322516-wekvet6f	284	1	Consistent	consistent	JJ
cord-322516-wekvet6f	284	2	with	with	IN
cord-322516-wekvet6f	284	3	this	this	DT
cord-322516-wekvet6f	284	4	idea	idea	NN
cord-322516-wekvet6f	284	5	,	,	,
cord-322516-wekvet6f	284	6	the	the	DT
cord-322516-wekvet6f	284	7	rate	rate	NN
cord-322516-wekvet6f	284	8	of	of	IN
cord-322516-wekvet6f	284	9	movement	movement	NN
cord-322516-wekvet6f	284	10	of	of	IN
cord-322516-wekvet6f	284	11	VSV	VSV	NNP
cord-322516-wekvet6f	284	12	G	G	NNP
cord-322516-wekvet6f	284	13	through	through	IN
cord-322516-wekvet6f	284	14	the	the	DT
cord-322516-wekvet6f	284	15	late	late	JJ
cord-322516-wekvet6f	284	16	Golgi	Golgi	NNP
cord-322516-wekvet6f	284	17	(	(	-LRB-
cord-322516-wekvet6f	284	18	measured	measure	VBN
cord-322516-wekvet6f	284	19	by	by	IN
cord-322516-wekvet6f	284	20	sialylation	sialylation	NN
cord-322516-wekvet6f	284	21	)	)	-RRB-
cord-322516-wekvet6f	284	22	was	be	VBD
cord-322516-wekvet6f	284	23	slowed	slow	VBN
cord-322516-wekvet6f	284	24	to	to	IN
cord-322516-wekvet6f	284	25	a	a	DT
cord-322516-wekvet6f	284	26	much	much	RB
cord-322516-wekvet6f	284	27	greater	great	JJR
cord-322516-wekvet6f	284	28	extent	extent	NN
cord-322516-wekvet6f	284	29	by	by	IN
cord-322516-wekvet6f	284	30	C	C	NNP
cord-322516-wekvet6f	284	31	6	6	CD
cord-322516-wekvet6f	284	32	Cer	Cer	NNP
cord-322516-wekvet6f	284	33	than	than	IN
cord-322516-wekvet6f	284	34	by	by	IN
cord-322516-wekvet6f	284	35	PDMP	PDMP	NNP
cord-322516-wekvet6f	284	36	(	(	-LRB-
cord-322516-wekvet6f	284	37	Rosenwald	Rosenwald	NNP
cord-322516-wekvet6f	284	38	and	and	CC
cord-322516-wekvet6f	284	39	Pagano	Pagano	NNP
cord-322516-wekvet6f	284	40	,	,	,
cord-322516-wekvet6f	284	41	1993	1993	CD
cord-322516-wekvet6f	284	42	)	)	-RRB-
cord-322516-wekvet6f	284	43	.	.	.
cord-322516-wekvet6f	285	1	It	-PRON-	PRP
cord-322516-wekvet6f	285	2	is	be	VBZ
cord-322516-wekvet6f	285	3	not	not	RB
cord-322516-wekvet6f	285	4	yet	yet	RB
cord-322516-wekvet6f	285	5	clear	clear	JJ
cord-322516-wekvet6f	285	6	how	how	WRB
cord-322516-wekvet6f	285	7	ceramide	ceramide	NN
cord-322516-wekvet6f	285	8	induces	induce	VBZ
cord-322516-wekvet6f	285	9	the	the	DT
cord-322516-wekvet6f	285	10	changes	change	NNS
cord-322516-wekvet6f	285	11	in	in	IN
cord-322516-wekvet6f	285	12	anterograde	anterograde	JJ
cord-322516-wekvet6f	285	13	traffic	traffic	NN
cord-322516-wekvet6f	285	14	and	and	CC
cord-322516-wekvet6f	285	15	protein	protein	NN
cord-322516-wekvet6f	285	16	localization	localization	NN
cord-322516-wekvet6f	285	17	.	.	.
cord-322516-wekvet6f	286	1	Recent	recent	JJ
cord-322516-wekvet6f	286	2	studies	study	NNS
cord-322516-wekvet6f	286	3	have	have	VBP
cord-322516-wekvet6f	286	4	shown	show	VBN
cord-322516-wekvet6f	286	5	that	that	DT
cord-322516-wekvet6f	286	6	ceramide	ceramide	NN
cord-322516-wekvet6f	286	7	(	(	-LRB-
cord-322516-wekvet6f	286	8	Hannun	Hannun	NNP
cord-322516-wekvet6f	286	9	,	,	,
cord-322516-wekvet6f	286	10	1994	1994	CD
cord-322516-wekvet6f	286	11	)	)	-RRB-
cord-322516-wekvet6f	286	12	and	and	CC
cord-322516-wekvet6f	286	13	its	-PRON-	PRP$
cord-322516-wekvet6f	286	14	metabolites	metabolite	NNS
cord-322516-wekvet6f	286	15	(	(	-LRB-
cord-322516-wekvet6f	286	16	Hakomori	Hakomori	NNP
cord-322516-wekvet6f	286	17	,	,	,
cord-322516-wekvet6f	286	18	1990	1990	CD
cord-322516-wekvet6f	286	19	)	)	-RRB-
cord-322516-wekvet6f	286	20	play	play	VBP
cord-322516-wekvet6f	286	21	a	a	DT
cord-322516-wekvet6f	286	22	major	major	JJ
cord-322516-wekvet6f	286	23	role	role	NN
cord-322516-wekvet6f	286	24	as	as	IN
cord-322516-wekvet6f	286	25	second	second	JJ
cord-322516-wekvet6f	286	26	messengers	messenger	NNS
cord-322516-wekvet6f	286	27	.	.	.
cord-322516-wekvet6f	287	1	Preliminary	preliminary	JJ
cord-322516-wekvet6f	287	2	experiments	experiment	NNS
cord-322516-wekvet6f	287	3	with	with	IN
cord-322516-wekvet6f	287	4	both	both	CC
cord-322516-wekvet6f	287	5	the	the	DT
cord-322516-wekvet6f	287	6	ceramidase	ceramidase	NN
cord-322516-wekvet6f	287	7	inhibitor	inhibitor	NN
cord-322516-wekvet6f	287	8	N	N	NNP
cord-322516-wekvet6f	287	9	-	-	HYPH
cord-322516-wekvet6f	287	10	oleoylethanolamine	oleoylethanolamine	NNP
cord-322516-wekvet6f	287	11	and	and	CC
cord-322516-wekvet6f	287	12	exogenously	exogenously	RB
cord-322516-wekvet6f	287	13	added	add	VBN
cord-322516-wekvet6f	287	14	sphingosine	sphingosine	NNP
cord-322516-wekvet6f	287	15	suggest	suggest	VBP
cord-322516-wekvet6f	287	16	that	that	IN
cord-322516-wekvet6f	287	17	the	the	DT
cord-322516-wekvet6f	287	18	ceramide	ceramide	NN
cord-322516-wekvet6f	287	19	breakdown	breakdown	NN
cord-322516-wekvet6f	287	20	product	product	NN
cord-322516-wekvet6f	287	21	sphingosine	sphingosine	NN
cord-322516-wekvet6f	287	22	does	do	VBZ
cord-322516-wekvet6f	287	23	not	not	RB
cord-322516-wekvet6f	287	24	play	play	VB
cord-322516-wekvet6f	287	25	a	a	DT
cord-322516-wekvet6f	287	26	role	role	NN
cord-322516-wekvet6f	287	27	in	in	IN
cord-322516-wekvet6f	287	28	the	the	DT
cord-322516-wekvet6f	287	29	localization	localization	NN
cord-322516-wekvet6f	287	30	of	of	IN
cord-322516-wekvet6f	287	31	IBV	IBV	NNP
cord-322516-wekvet6f	287	32	M	M	NNP
cord-322516-wekvet6f	287	33	(	(	-LRB-
cord-322516-wekvet6f	287	34	Maceyka	Maceyka	NNP
cord-322516-wekvet6f	287	35	,	,	,
cord-322516-wekvet6f	287	36	M.	M.	NNP
cord-322516-wekvet6f	287	37	,	,	,
cord-322516-wekvet6f	287	38	and	and	CC
cord-322516-wekvet6f	287	39	C.	C.	NNP
cord-322516-wekvet6f	287	40	Machamer	Machamer	NNP
cord-322516-wekvet6f	287	41	,	,	,
cord-322516-wekvet6f	287	42	unpublished	unpublished	JJ
cord-322516-wekvet6f	287	43	observations	observation	NNS
cord-322516-wekvet6f	287	44	)	)	-RRB-
cord-322516-wekvet6f	287	45	.	.	.
cord-322516-wekvet6f	288	1	Ceramide	ceramide	NN
cord-322516-wekvet6f	288	2	activates	activate	VBZ
cord-322516-wekvet6f	288	3	a	a	DT
cord-322516-wekvet6f	288	4	cytosolic	cytosolic	JJ
cord-322516-wekvet6f	288	5	protein	protein	NN
cord-322516-wekvet6f	288	6	phosphatase	phosphatase	NN
cord-322516-wekvet6f	288	7	(	(	-LRB-
cord-322516-wekvet6f	288	8	Dobrowsky	Dobrowsky	NNP
cord-322516-wekvet6f	288	9	and	and	CC
cord-322516-wekvet6f	288	10	Hannun	Hannun	NNP
cord-322516-wekvet6f	288	11	,	,	,
cord-322516-wekvet6f	288	12	1992	1992	CD
cord-322516-wekvet6f	288	13	;	;	:
cord-322516-wekvet6f	288	14	Wolff	Wolff	NNP
cord-322516-wekvet6f	288	15	et	et	NNP
cord-322516-wekvet6f	288	16	al	al	NNP
cord-322516-wekvet6f	288	17	.	.	NNP
cord-322516-wekvet6f	288	18	,	,	,
cord-322516-wekvet6f	288	19	1994	1994	CD
cord-322516-wekvet6f	288	20	)	)	-RRB-
cord-322516-wekvet6f	288	21	that	that	WDT
cord-322516-wekvet6f	288	22	can	can	MD
cord-322516-wekvet6f	288	23	be	be	VB
cord-322516-wekvet6f	288	24	inhibited	inhibit	VBN
cord-322516-wekvet6f	288	25	by	by	IN
cord-322516-wekvet6f	288	26	okadaic	okadaic	JJ
cord-322516-wekvet6f	288	27	acid	acid	NN
cord-322516-wekvet6f	288	28	.	.	.
cord-322516-wekvet6f	289	1	Preliminary	preliminary	JJ
cord-322516-wekvet6f	289	2	experiments	experiment	NNS
cord-322516-wekvet6f	289	3	suggest	suggest	VBP
cord-322516-wekvet6f	289	4	that	that	IN
cord-322516-wekvet6f	289	5	okadaic	okadaic	JJ
cord-322516-wekvet6f	289	6	acid	acid	NN
cord-322516-wekvet6f	289	7	does	do	VBZ
cord-322516-wekvet6f	289	8	not	not	RB
cord-322516-wekvet6f	289	9	block	block	VB
cord-322516-wekvet6f	289	10	the	the	DT
cord-322516-wekvet6f	289	11	PDMPinduced	pdmpinduced	JJ
cord-322516-wekvet6f	289	12	changes	change	NNS
cord-322516-wekvet6f	289	13	(	(	-LRB-
cord-322516-wekvet6f	289	14	Maceyka	Maceyka	NNP
cord-322516-wekvet6f	289	15	,	,	,
cord-322516-wekvet6f	289	16	M.	M.	NNP
cord-322516-wekvet6f	289	17	,	,	,
cord-322516-wekvet6f	289	18	and	and	CC
cord-322516-wekvet6f	289	19	C.	C.	NNP
cord-322516-wekvet6f	289	20	Machamer	Machamer	NNP
cord-322516-wekvet6f	289	21	,	,	,
cord-322516-wekvet6f	289	22	unpublished	unpublished	JJ
cord-322516-wekvet6f	289	23	observations	observation	NNS
cord-322516-wekvet6f	289	24	)	)	-RRB-
cord-322516-wekvet6f	289	25	.	.	.
cord-322516-wekvet6f	290	1	Ceramide	ceramide	NN
cord-322516-wekvet6f	290	2	could	could	MD
cord-322516-wekvet6f	290	3	be	be	VB
cord-322516-wekvet6f	290	4	activating	activate	VBG
cord-322516-wekvet6f	290	5	a	a	DT
cord-322516-wekvet6f	290	6	protein	protein	NN
cord-322516-wekvet6f	290	7	kinase	kinase	NN
cord-322516-wekvet6f	290	8	(	(	-LRB-
cord-322516-wekvet6f	290	9	Mathias	Mathias	NNP
cord-322516-wekvet6f	290	10	et	et	NNP
cord-322516-wekvet6f	290	11	al	al	NNP
cord-322516-wekvet6f	290	12	.	.	NNP
cord-322516-wekvet6f	290	13	,	,	,
cord-322516-wekvet6f	290	14	1991	1991	CD
cord-322516-wekvet6f	290	15	)	)	-RRB-
cord-322516-wekvet6f	290	16	,	,	,
cord-322516-wekvet6f	290	17	but	but	CC
cord-322516-wekvet6f	290	18	this	this	DT
cord-322516-wekvet6f	290	19	kinase	kinase	NN
cord-322516-wekvet6f	290	20	has	have	VBZ
cord-322516-wekvet6f	290	21	not	not	RB
cord-322516-wekvet6f	290	22	been	be	VBN
cord-322516-wekvet6f	290	23	fully	fully	RB
cord-322516-wekvet6f	290	24	characterized	characterize	VBN
cord-322516-wekvet6f	290	25	.	.	.
cord-322516-wekvet6f	291	1	Another	another	DT
cord-322516-wekvet6f	291	2	possibility	possibility	NN
cord-322516-wekvet6f	291	3	is	be	VBZ
cord-322516-wekvet6f	291	4	that	that	DT
cord-322516-wekvet6f	291	5	increased	increase	VBN
cord-322516-wekvet6f	291	6	ceramide	ceramide	NN
cord-322516-wekvet6f	291	7	within	within	IN
cord-322516-wekvet6f	291	8	the	the	DT
cord-322516-wekvet6f	291	9	lipid	lipid	NN
cord-322516-wekvet6f	291	10	bilayer	bilayer	NN
cord-322516-wekvet6f	291	11	directly	directly	RB
cord-322516-wekvet6f	291	12	affects	affect	VBZ
cord-322516-wekvet6f	291	13	the	the	DT
cord-322516-wekvet6f	291	14	localization	localization	NN
cord-322516-wekvet6f	291	15	of	of	IN
cord-322516-wekvet6f	291	16	IBV	IBV	NNP
cord-322516-wekvet6f	291	17	M.	M.	NNP
cord-322516-wekvet6f	291	18	Earlier	Earlier	NNP
cord-322516-wekvet6f	291	19	work	work	NN
cord-322516-wekvet6f	291	20	from	from	IN
cord-322516-wekvet6f	291	21	our	-PRON-	PRP$
cord-322516-wekvet6f	291	22	laboratory	laboratory	NN
cord-322516-wekvet6f	291	23	showed	show	VBD
cord-322516-wekvet6f	291	24	that	that	IN
cord-322516-wekvet6f	291	25	the	the	DT
cord-322516-wekvet6f	291	26	first	first	JJ
cord-322516-wekvet6f	291	27	transmembrane	transmembrane	NN
cord-322516-wekvet6f	291	28	domain	domain	NN
cord-322516-wekvet6f	291	29	of	of	IN
cord-322516-wekvet6f	291	30	IBV	IBV	NNP
cord-322516-wekvet6f	291	31	M	M	NNP
cord-322516-wekvet6f	291	32	can	can	MD
cord-322516-wekvet6f	291	33	target	target	VB
cord-322516-wekvet6f	291	34	chimeras	chimera	NNS
cord-322516-wekvet6f	291	35	to	to	IN
cord-322516-wekvet6f	291	36	the	the	DT
cord-322516-wekvet6f	291	37	CGN	CGN	NNP
cord-322516-wekvet6f	291	38	(	(	-LRB-
cord-322516-wekvet6f	291	39	Swift	Swift	NNP
cord-322516-wekvet6f	291	40	and	and	CC
cord-322516-wekvet6f	291	41	Machamer	Machamer	NNP
cord-322516-wekvet6f	291	42	,	,	,
cord-322516-wekvet6f	291	43	1991	1991	CD
cord-322516-wekvet6f	291	44	;	;	:
cord-322516-wekvet6f	291	45	Machamer	Machamer	NNP
cord-322516-wekvet6f	291	46	et	et	NNP
cord-322516-wekvet6f	291	47	al	al	NNP
cord-322516-wekvet6f	291	48	.	.	NNP
cord-322516-wekvet6f	291	49	,	,	,
cord-322516-wekvet6f	291	50	1993	1993	CD
cord-322516-wekvet6f	291	51	)	)	-RRB-
cord-322516-wekvet6f	291	52	.	.	.
cord-322516-wekvet6f	292	1	It	-PRON-	PRP
cord-322516-wekvet6f	292	2	is	be	VBZ
cord-322516-wekvet6f	292	3	possible	possible	JJ
cord-322516-wekvet6f	292	4	that	that	IN
cord-322516-wekvet6f	292	5	CGN	CGN	NNP
cord-322516-wekvet6f	292	6	bilayers	bilayer	NNS
cord-322516-wekvet6f	292	7	have	have	VBP
cord-322516-wekvet6f	292	8	distinct	distinct	JJ
cord-322516-wekvet6f	292	9	lipid	lipid	NN
cord-322516-wekvet6f	292	10	domains	domain	NNS
cord-322516-wekvet6f	292	11	,	,	,
cord-322516-wekvet6f	292	12	and	and	CC
cord-322516-wekvet6f	292	13	that	that	IN
cord-322516-wekvet6f	292	14	these	these	DT
cord-322516-wekvet6f	292	15	domains	domain	NNS
cord-322516-wekvet6f	292	16	contain	contain	VBP
cord-322516-wekvet6f	292	17	different	different	JJ
cord-322516-wekvet6f	292	18	sets	set	NNS
cord-322516-wekvet6f	292	19	of	of	IN
cord-322516-wekvet6f	292	20	proteins	protein	NNS
cord-322516-wekvet6f	292	21	,	,	,
cord-322516-wekvet6f	292	22	analogous	analogous	JJ
cord-322516-wekvet6f	292	23	to	to	IN
cord-322516-wekvet6f	292	24	glycosphingolipid	glycosphingolipid	NN
cord-322516-wekvet6f	292	25	rafts	raft	NNS
cord-322516-wekvet6f	292	26	.	.	.
cord-322516-wekvet6f	293	1	Segregation	segregation	NN
cord-322516-wekvet6f	293	2	of	of	IN
cord-322516-wekvet6f	293	3	membrane	membrane	NN
cord-322516-wekvet6f	293	4	proteins	protein	NNS
cord-322516-wekvet6f	293	5	involved	involve	VBN
cord-322516-wekvet6f	293	6	in	in	IN
cord-322516-wekvet6f	293	7	vesicular	vesicular	JJ
cord-322516-wekvet6f	293	8	traffic	traffic	NN
cord-322516-wekvet6f	293	9	,	,	,
cord-322516-wekvet6f	293	10	such	such	JJ
cord-322516-wekvet6f	293	11	as	as	IN
cord-322516-wekvet6f	293	12	SNAREs	SNAREs	NNP
cord-322516-wekvet6f	293	13	,	,	,
cord-322516-wekvet6f	293	14	would	would	MD
cord-322516-wekvet6f	293	15	lead	lead	VB
cord-322516-wekvet6f	293	16	to	to	IN
cord-322516-wekvet6f	293	17	mobile	mobile	JJ
cord-322516-wekvet6f	293	18	and	and	CC
cord-322516-wekvet6f	293	19	immobile	immobile	JJ
cord-322516-wekvet6f	293	20	domains	domain	NNS
cord-322516-wekvet6f	293	21	.	.	.
cord-322516-wekvet6f	294	1	We	-PRON-	PRP
cord-322516-wekvet6f	294	2	hypothesize	hypothesize	VBP
cord-322516-wekvet6f	294	3	that	that	IN
cord-322516-wekvet6f	294	4	under	under	IN
cord-322516-wekvet6f	294	5	normal	normal	JJ
cord-322516-wekvet6f	294	6	conditions	condition	NNS
cord-322516-wekvet6f	294	7	,	,	,
cord-322516-wekvet6f	294	8	IBV	IBV	NNP
cord-322516-wekvet6f	294	9	M	M	NNP
cord-322516-wekvet6f	294	10	would	would	MD
cord-322516-wekvet6f	294	11	be	be	VB
cord-322516-wekvet6f	294	12	targeted	target	VBN
cord-322516-wekvet6f	294	13	to	to	IN
cord-322516-wekvet6f	294	14	an	an	DT
cord-322516-wekvet6f	294	15	immobile	immobile	JJ
cord-322516-wekvet6f	294	16	domain	domain	NN
cord-322516-wekvet6f	294	17	and	and	CC
cord-322516-wekvet6f	294	18	escaped	escape	VBD
cord-322516-wekvet6f	294	19	molecules	molecule	NNS
cord-322516-wekvet6f	294	20	would	would	MD
cord-322516-wekvet6f	294	21	be	be	VB
cord-322516-wekvet6f	294	22	cycled	cycle	VBN
cord-322516-wekvet6f	294	23	back	back	RB
cord-322516-wekvet6f	294	24	through	through	IN
cord-322516-wekvet6f	294	25	the	the	DT
cord-322516-wekvet6f	294	26	ER	er	NN
cord-322516-wekvet6f	294	27	.	.	.
cord-322516-wekvet6f	295	1	Elevated	elevated	JJ
cord-322516-wekvet6f	295	2	levels	level	NNS
cord-322516-wekvet6f	295	3	of	of	IN
cord-322516-wekvet6f	295	4	ceramide	ceramide	NN
cord-322516-wekvet6f	295	5	could	could	MD
cord-322516-wekvet6f	295	6	disrupt	disrupt	VB
cord-322516-wekvet6f	295	7	these	these	DT
cord-322516-wekvet6f	295	8	immobile	immobile	JJ
cord-322516-wekvet6f	295	9	lipid	lipid	NN
cord-322516-wekvet6f	295	10	domains	domain	NNS
cord-322516-wekvet6f	295	11	,	,	,
cord-322516-wekvet6f	295	12	inducing	induce	VBG
cord-322516-wekvet6f	295	13	IBV	IBV	NNP
cord-322516-wekvet6f	295	14	M	M	NNP
cord-322516-wekvet6f	295	15	to	to	TO
cord-322516-wekvet6f	295	16	cycle	cycle	VB
cord-322516-wekvet6f	295	17	.	.	.
cord-322516-wekvet6f	296	1	Alternatively	alternatively	RB
cord-322516-wekvet6f	296	2	,	,	,
cord-322516-wekvet6f	296	3	perhaps	perhaps	RB
cord-322516-wekvet6f	296	4	ceramide	ceramide	NN
cord-322516-wekvet6f	296	5	binds	bind	VBZ
cord-322516-wekvet6f	296	6	to	to	IN
cord-322516-wekvet6f	296	7	IBV	IBV	NNP
cord-322516-wekvet6f	296	8	M	M	NNP
cord-322516-wekvet6f	296	9	transmembrane	transmembrane	NN
cord-322516-wekvet6f	296	10	domains	domain	NNS
cord-322516-wekvet6f	296	11	,	,	,
cord-322516-wekvet6f	296	12	preventing	prevent	VBG
cord-322516-wekvet6f	296	13	an	an	DT
cord-322516-wekvet6f	296	14	interaction	interaction	NN
cord-322516-wekvet6f	296	15	with	with	IN
cord-322516-wekvet6f	296	16	immobile	immobile	JJ
cord-322516-wekvet6f	296	17	lipid	lipid	NN
cord-322516-wekvet6f	296	18	domains	domain	NNS
cord-322516-wekvet6f	296	19	.	.	.
cord-322516-wekvet6f	297	1	Metabolic	metabolic	JJ
cord-322516-wekvet6f	297	2	effects	effect	NNS
cord-322516-wekvet6f	297	3	of	of	IN
cord-322516-wekvet6f	297	4	shortchain	shortchain	NN
cord-322516-wekvet6f	297	5	ceramide	ceramide	NN
cord-322516-wekvet6f	297	6	and	and	CC
cord-322516-wekvet6f	297	7	glucosylceramide	glucosylceramide	NN
cord-322516-wekvet6f	297	8	on	on	IN
cord-322516-wekvet6f	297	9	sphingolipids	sphingolipid	NNS
cord-322516-wekvet6f	297	10	and	and	CC
cord-322516-wekvet6f	297	11	protein	protein	NN
cord-322516-wekvet6f	297	12	kinase	kinase	NN
cord-322516-wekvet6f	297	13	C	C	NNP
cord-322516-wekvet6f	297	14	Inhibition	Inhibition	NNP
cord-322516-wekvet6f	297	15	of	of	IN
cord-322516-wekvet6f	297	16	glucosylceramide	glucosylceramide	JJ
cord-322516-wekvet6f	297	17	synthase	synthase	NN
cord-322516-wekvet6f	297	18	by	by	IN
cord-322516-wekvet6f	297	19	synthase	synthase	NN
cord-322516-wekvet6f	297	20	inhibitors	inhibitor	NNS
cord-322516-wekvet6f	297	21	and	and	CC
cord-322516-wekvet6f	297	22	ceramide	ceramide	NN
cord-322516-wekvet6f	297	23	A	a	DT
cord-322516-wekvet6f	297	24	rapid	rapid	JJ
cord-322516-wekvet6f	297	25	and	and	CC
cord-322516-wekvet6f	297	26	sensitive	sensitive	JJ
cord-322516-wekvet6f	297	27	method	method	NN
cord-322516-wekvet6f	297	28	for	for	IN
cord-322516-wekvet6f	297	29	the	the	DT
cord-322516-wekvet6f	297	30	quantitation	quantitation	NN
cord-322516-wekvet6f	297	31	of	of	IN
cord-322516-wekvet6f	297	32	microgram	microgram	NN
cord-322516-wekvet6f	297	33	quantities	quantity	NNS
cord-322516-wekvet6f	297	34	of	of	IN
cord-322516-wekvet6f	297	35	protein	protein	NN
cord-322516-wekvet6f	297	36	utilizing	utilize	VBG
cord-322516-wekvet6f	297	37	the	the	DT
cord-322516-wekvet6f	297	38	principle	principle	NN
cord-322516-wekvet6f	297	39	of	of	IN
cord-322516-wekvet6f	297	40	protein	protein	NN
cord-322516-wekvet6f	297	41	-	-	HYPH
cord-322516-wekvet6f	297	42	dye	dye	NN
cord-322516-wekvet6f	297	43	binding	bind	VBG
cord-322516-wekvet6f	297	44	A	a	DT
cord-322516-wekvet6f	297	45	rapid	rapid	JJ
cord-322516-wekvet6f	297	46	method	method	NN
cord-322516-wekvet6f	297	47	of	of	IN
cord-322516-wekvet6f	297	48	total	total	JJ
cord-322516-wekvet6f	297	49	lipid	lipid	NN
cord-322516-wekvet6f	297	50	extraction	extraction	NN
cord-322516-wekvet6f	297	51	and	and	CC
cord-322516-wekvet6f	297	52	purification	purification	NN
cord-322516-wekvet6f	297	53	Ceramide	Ceramide	NNP
cord-322516-wekvet6f	297	54	as	as	IN
cord-322516-wekvet6f	297	55	a	a	DT
cord-322516-wekvet6f	297	56	modulator	modulator	NN
cord-322516-wekvet6f	297	57	of	of	IN
cord-322516-wekvet6f	297	58	endocytosis	endocytosis	NN
cord-322516-wekvet6f	297	59	Heterogeneous	heterogeneous	JJ
cord-322516-wekvet6f	297	60	distribution	distribution	NN
cord-322516-wekvet6f	297	61	of	of	IN
cord-322516-wekvet6f	297	62	an	an	DT
cord-322516-wekvet6f	297	63	unusual	unusual	JJ
cord-322516-wekvet6f	297	64	phospholipid	phospholipid	NN
cord-322516-wekvet6f	297	65	in	in	IN
cord-322516-wekvet6f	297	66	the	the	DT
cord-322516-wekvet6f	297	67	Golgi	Golgi	NNP
cord-322516-wekvet6f	297	68	complex	complex	JJ
cord-322516-wekvet6f	297	69	Golgi	Golgi	NNP
cord-322516-wekvet6f	297	70	dispersal	dispersal	NN
cord-322516-wekvet6f	297	71	during	during	IN
cord-322516-wekvet6f	297	72	microtubule	microtubule	JJ
cord-322516-wekvet6f	297	73	disruption	disruption	NN
cord-322516-wekvet6f	297	74	:	:	:
cord-322516-wekvet6f	297	75	regeneration	regeneration	NN
cord-322516-wekvet6f	297	76	of	of	IN
cord-322516-wekvet6f	297	77	Golgi	Golgi	NNP
cord-322516-wekvet6f	297	78	stacks	stack	NNS
cord-322516-wekvet6f	297	79	at	at	IN
cord-322516-wekvet6f	297	80	peripheral	peripheral	JJ
cord-322516-wekvet6f	297	81	endoplasmic	endoplasmic	NN
cord-322516-wekvet6f	297	82	reticulum	reticulum	NN
cord-322516-wekvet6f	297	83	exit	exit	NN
cord-322516-wekvet6f	297	84	sites	site	NNS
cord-322516-wekvet6f	297	85	Diffusional	diffusional	JJ
cord-322516-wekvet6f	297	86	mobility	mobility	NN
cord-322516-wekvet6f	297	87	of	of	IN
cord-322516-wekvet6f	297	88	Golgi	Golgi	NNP
cord-322516-wekvet6f	297	89	proteins	protein	NNS
cord-322516-wekvet6f	297	90	in	in	IN
cord-322516-wekvet6f	297	91	membranes	membrane	NNS
cord-322516-wekvet6f	297	92	of	of	IN
cord-322516-wekvet6f	297	93	living	living	NN
cord-322516-wekvet6f	297	94	cells	cell	NNS
cord-322516-wekvet6f	297	95	Golgi	Golgi	NNP
cord-322516-wekvet6f	297	96	localization	localization	NN
cord-322516-wekvet6f	297	97	of	of	IN
cord-322516-wekvet6f	297	98	glycosyltransferases	glycosyltransferase	NNS
cord-322516-wekvet6f	297	99	:	:	:
cord-322516-wekvet6f	297	100	more	more	JJR
cord-322516-wekvet6f	297	101	questions	question	NNS
cord-322516-wekvet6f	297	102	than	than	IN
cord-322516-wekvet6f	297	103	answers	answer	NNS
cord-322516-wekvet6f	298	1	Ceramide	ceramide	NN
cord-322516-wekvet6f	298	2	stimulates	stimulate	VBZ
cord-322516-wekvet6f	298	3	a	a	DT
cord-322516-wekvet6f	298	4	cytosolic	cytosolic	JJ
cord-322516-wekvet6f	298	5	protein	protein	NN
cord-322516-wekvet6f	298	6	phosphatase	phosphatase	NN
cord-322516-wekvet6f	298	7	Determination	determination	NN
cord-322516-wekvet6f	298	8	of	of	IN
cord-322516-wekvet6f	298	9	the	the	DT
cord-322516-wekvet6f	298	10	intracellular	intracellular	JJ
cord-322516-wekvet6f	298	11	sites	site	NNS
cord-322516-wekvet6f	298	12	and	and	CC
cord-322516-wekvet6f	298	13	topology	topology	NN
cord-322516-wekvet6f	298	14	of	of	IN
cord-322516-wekvet6f	298	15	glucosylceramide	glucosylceramide	JJ
cord-322516-wekvet6f	298	16	synthesis	synthesis	NN
cord-322516-wekvet6f	298	17	in	in	IN
cord-322516-wekvet6f	298	18	rat	rat	NN
cord-322516-wekvet6f	298	19	liver	liver	NN
cord-322516-wekvet6f	298	20	Sphingomyelin	Sphingomyelin	NNP
cord-322516-wekvet6f	298	21	synthesis	synthesis	NN
cord-322516-wekvet6f	298	22	in	in	IN
cord-322516-wekvet6f	298	23	rat	rat	NN
cord-322516-wekvet6f	298	24	liver	liver	NN
cord-322516-wekvet6f	298	25	occurs	occur	VBZ
cord-322516-wekvet6f	298	26	predominantly	predominantly	RB
cord-322516-wekvet6f	298	27	at	at	IN
cord-322516-wekvet6f	298	28	the	the	DT
cord-322516-wekvet6f	298	29	cis	cis	NNP
cord-322516-wekvet6f	298	30	and	and	CC
cord-322516-wekvet6f	298	31	medial	medial	NNP
cord-322516-wekvet6f	298	32	cisternae	cisternae	NNP
cord-322516-wekvet6f	298	33	of	of	IN
cord-322516-wekvet6f	298	34	the	the	DT
cord-322516-wekvet6f	298	35	Golgi	Golgi	NNP
cord-322516-wekvet6f	298	36	apparatus	apparatus	NN
cord-322516-wekvet6f	298	37	Bifunctional	Bifunctional	NNP
cord-322516-wekvet6f	298	38	role	role	NN
cord-322516-wekvet6f	298	39	of	of	IN
cord-322516-wekvet6f	298	40	glycosphingolipids	glycosphingolipid	NNS
cord-322516-wekvet6f	298	41	.	.	.
cord-322516-wekvet6f	299	1	Modulators	modulator	NNS
cord-322516-wekvet6f	299	2	for	for	IN
cord-322516-wekvet6f	299	3	transmembrane	transmembrane	NN
cord-322516-wekvet6f	299	4	signaling	signaling	NN
cord-322516-wekvet6f	299	5	and	and	CC
cord-322516-wekvet6f	299	6	mediators	mediator	NNS
cord-322516-wekvet6f	299	7	for	for	IN
cord-322516-wekvet6f	299	8	cellular	cellular	JJ
cord-322516-wekvet6f	299	9	interactions	interaction	NNS
cord-322516-wekvet6f	300	1	The	the	DT
cord-322516-wekvet6f	300	2	sphingomyelin	sphingomyelin	NN
cord-322516-wekvet6f	300	3	cycle	cycle	NN
cord-322516-wekvet6f	300	4	and	and	CC
cord-322516-wekvet6f	300	5	the	the	DT
cord-322516-wekvet6f	300	6	second	second	JJ
cord-322516-wekvet6f	300	7	messenger	messenger	NN
cord-322516-wekvet6f	300	8	function	function	NN
cord-322516-wekvet6f	300	9	of	of	IN
cord-322516-wekvet6f	300	10	ceramide	ceramide	NN
cord-322516-wekvet6f	300	11	Thin	thin	JJ
cord-322516-wekvet6f	300	12	-	-	HYPH
cord-322516-wekvet6f	300	13	layer	layer	NN
cord-322516-wekvet6f	300	14	chromotography	chromotography	NNP
cord-322516-wekvet6f	300	15	Ceramide	ceramide	NN
cord-322516-wekvet6f	300	16	synthesis	synthesis	NN
cord-322516-wekvet6f	300	17	enhances	enhance	VBZ
cord-322516-wekvet6f	300	18	transport	transport	NN
cord-322516-wekvet6f	300	19	of	of	IN
cord-322516-wekvet6f	300	20	GPI	GPI	NNP
cord-322516-wekvet6f	300	21	-	-	HYPH
cord-322516-wekvet6f	300	22	anchored	anchor	VBN
cord-322516-wekvet6f	300	23	proteins	protein	NNS
cord-322516-wekvet6f	300	24	to	to	IN
cord-322516-wekvet6f	300	25	the	the	DT
cord-322516-wekvet6f	300	26	Golgi	Golgi	NNP
cord-322516-wekvet6f	300	27	apparatus	apparatus	NN
cord-322516-wekvet6f	300	28	in	in	IN
cord-322516-wekvet6f	300	29	yeast	yeast	NN
cord-322516-wekvet6f	300	30	Preparation	preparation	NN
cord-322516-wekvet6f	300	31	of	of	IN
cord-322516-wekvet6f	300	32	the	the	DT
cord-322516-wekvet6f	300	33	active	active	JJ
cord-322516-wekvet6f	300	34	isomer	isomer	NN
cord-322516-wekvet6f	300	35	of	of	IN
cord-322516-wekvet6f	300	36	1-phenyl-2-decanoylamino-3-morpholino-1-propanol	1-phenyl-2-decanoylamino-3-morpholino-1-propanol	CD
cord-322516-wekvet6f	300	37	,	,	,
cord-322516-wekvet6f	300	38	inhibitor	inhibitor	NN
cord-322516-wekvet6f	300	39	of	of	IN
cord-322516-wekvet6f	300	40	murine	murine	JJ
cord-322516-wekvet6f	300	41	glucocerebroside	glucocerebroside	JJ
cord-322516-wekvet6f	300	42	synthetase	synthetase	NN
cord-322516-wekvet6f	300	43	Phospholipid	Phospholipid	NNP
cord-322516-wekvet6f	300	44	class	class	NN
cord-322516-wekvet6f	300	45	and	and	CC
cord-322516-wekvet6f	300	46	fatty	fatty	JJ
cord-322516-wekvet6f	300	47	acid	acid	NN
cord-322516-wekvet6f	300	48	composition	composition	NN
cord-322516-wekvet6f	300	49	of	of	IN
cord-322516-wekvet6f	300	50	Golgi	Golgi	NNP
cord-322516-wekvet6f	300	51	apparatus	apparatus	NN
cord-322516-wekvet6f	300	52	isolated	isolate	VBN
cord-322516-wekvet6f	300	53	from	from	IN
cord-322516-wekvet6f	300	54	rat	rat	NN
cord-322516-wekvet6f	300	55	liver	liver	NN
cord-322516-wekvet6f	300	56	and	and	CC
cord-322516-wekvet6f	300	57	comparison	comparison	NN
cord-322516-wekvet6f	300	58	with	with	IN
cord-322516-wekvet6f	300	59	other	other	JJ
cord-322516-wekvet6f	300	60	cell	cell	NN
cord-322516-wekvet6f	300	61	fractions	fraction	NNS
cord-322516-wekvet6f	300	62	Molecular	molecular	JJ
cord-322516-wekvet6f	300	63	cloning	clone	VBG
cord-322516-wekvet6f	300	64	and	and	CC
cord-322516-wekvet6f	300	65	expression	expression	NN
cord-322516-wekvet6f	300	66	of	of	IN
cord-322516-wekvet6f	300	67	a	a	DT
cord-322516-wekvet6f	300	68	58-kDa	58-kda	CD
cord-322516-wekvet6f	300	69	cis	cis	NNP
cord-322516-wekvet6f	300	70	-	-	HYPH
cord-322516-wekvet6f	300	71	Golgi	Golgi	NNP
cord-322516-wekvet6f	300	72	and	and	CC
cord-322516-wekvet6f	300	73	intermediate	intermediate	JJ
cord-322516-wekvet6f	300	74	compartment	compartment	NN
cord-322516-wekvet6f	300	75	protein	protein	NN
cord-322516-wekvet6f	300	76	Giantin	Giantin	NNP
cord-322516-wekvet6f	300	77	,	,	,
cord-322516-wekvet6f	300	78	a	a	DT
cord-322516-wekvet6f	300	79	novel	novel	NN
cord-322516-wekvet6f	300	80	conserved	conserve	VBN
cord-322516-wekvet6f	300	81	Golgi	Golgi	NNP
cord-322516-wekvet6f	300	82	membrane	membrane	NN
cord-322516-wekvet6f	300	83	protein	protein	NN
cord-322516-wekvet6f	300	84	containing	contain	VBG
cord-322516-wekvet6f	300	85	a	a	DT
cord-322516-wekvet6f	300	86	cytoplasmic	cytoplasmic	JJ
cord-322516-wekvet6f	300	87	domain	domain	NN
cord-322516-wekvet6f	300	88	of	of	IN
cord-322516-wekvet6f	300	89	at	at	IN
cord-322516-wekvet6f	300	90	least	least	JJS
cord-322516-wekvet6f	300	91	350kDa	350kda	CD
cord-322516-wekvet6f	300	92	Microtubule	Microtubule	NNP
cord-322516-wekvet6f	300	93	-	-	HYPH
cord-322516-wekvet6f	300	94	dependent	dependent	JJ
cord-322516-wekvet6f	300	95	retrograde	retrograde	JJ
cord-322516-wekvet6f	300	96	transport	transport	NN
cord-322516-wekvet6f	300	97	of	of	IN
cord-322516-wekvet6f	300	98	proteins	protein	NNS
cord-322516-wekvet6f	300	99	into	into	IN
cord-322516-wekvet6f	300	100	the	the	DT
cord-322516-wekvet6f	300	101	ER	ER	NNP
cord-322516-wekvet6f	300	102	in	in	IN
cord-322516-wekvet6f	300	103	the	the	DT
cord-322516-wekvet6f	300	104	presence	presence	NN
cord-322516-wekvet6f	300	105	of	of	IN
cord-322516-wekvet6f	300	106	brefeldin	brefeldin	NNP
cord-322516-wekvet6f	301	1	A	a	DT
cord-322516-wekvet6f	301	2	suggests	suggest	VBZ
cord-322516-wekvet6f	301	3	an	an	DT
cord-322516-wekvet6f	301	4	ER	ER	NNP
cord-322516-wekvet6f	301	5	recycling	recycling	NN
cord-322516-wekvet6f	301	6	pathway	pathway	NN
cord-322516-wekvet6f	301	7	Golgi	Golgi	NNP
cord-322516-wekvet6f	301	8	retention	retention	NN
cord-322516-wekvet6f	301	9	signals	signal	NNS
cord-322516-wekvet6f	301	10	:	:	:
cord-322516-wekvet6f	301	11	do	do	VBP
cord-322516-wekvet6f	301	12	membranes	membrane	NNS
cord-322516-wekvet6f	301	13	hold	hold	VB
cord-322516-wekvet6f	301	14	the	the	DT
cord-322516-wekvet6f	301	15	key	key	NN
cord-322516-wekvet6f	301	16	?	?	.
cord-322516-wekvet6f	302	1	A	a	DT
cord-322516-wekvet6f	302	2	specific	specific	JJ
cord-322516-wekvet6f	302	3	membrane	membrane	NN
cord-322516-wekvet6f	302	4	-	-	HYPH
cord-322516-wekvet6f	302	5	spanning	span	VBG
cord-322516-wekvet6f	302	6	domain	domain	NN
cord-322516-wekvet6f	302	7	of	of	IN
cord-322516-wekvet6f	302	8	a	a	DT
cord-322516-wekvet6f	302	9	coronavirus	coronavirus	NN
cord-322516-wekvet6f	302	10	E1	e1	NN
cord-322516-wekvet6f	302	11	glycoprotein	glycoprotein	NN
cord-322516-wekvet6f	302	12	is	be	VBZ
cord-322516-wekvet6f	302	13	required	require	VBN
cord-322516-wekvet6f	302	14	for	for	IN
cord-322516-wekvet6f	302	15	its	-PRON-	PRP$
cord-322516-wekvet6f	302	16	retention	retention	NN
cord-322516-wekvet6f	302	17	in	in	IN
cord-322516-wekvet6f	302	18	the	the	DT
cord-322516-wekvet6f	302	19	Golgi	Golgi	NNP
cord-322516-wekvet6f	302	20	region	region	NN
cord-322516-wekvet6f	303	1	The	the	DT
cord-322516-wekvet6f	303	2	avian	avian	JJ
cord-322516-wekvet6f	303	3	coronavirus	coronavirus	NN
cord-322516-wekvet6f	303	4	E1	e1	NN
cord-322516-wekvet6f	303	5	protein	protein	NN
cord-322516-wekvet6f	303	6	is	be	VBZ
cord-322516-wekvet6f	303	7	targeted	target	VBN
cord-322516-wekvet6f	303	8	to	to	IN
cord-322516-wekvet6f	303	9	the	the	DT
cord-322516-wekvet6f	303	10	cis	cis	NNP
cord-322516-wekvet6f	303	11	Golgi	Golgi	NNP
cord-322516-wekvet6f	303	12	Retention	Retention	NNP
cord-322516-wekvet6f	303	13	of	of	IN
cord-322516-wekvet6f	303	14	a	a	DT
cord-322516-wekvet6f	303	15	cis	cis	NNP
cord-322516-wekvet6f	303	16	Golgi	Golgi	NNP
cord-322516-wekvet6f	303	17	protein	protein	NN
cord-322516-wekvet6f	303	18	requires	require	VBZ
cord-322516-wekvet6f	303	19	polar	polar	JJ
cord-322516-wekvet6f	303	20	residues	residue	NNS
cord-322516-wekvet6f	303	21	on	on	IN
cord-322516-wekvet6f	303	22	one	one	CD
cord-322516-wekvet6f	303	23	face	face	NN
cord-322516-wekvet6f	303	24	of	of	IN
cord-322516-wekvet6f	303	25	a	a	DT
cord-322516-wekvet6f	303	26	predicted	predict	VBN
cord-322516-wekvet6f	303	27	␣	␣	NN
cord-322516-wekvet6f	303	28	-helix	-helix	NN
cord-322516-wekvet6f	303	29	in	in	IN
cord-322516-wekvet6f	303	30	the	the	DT
cord-322516-wekvet6f	303	31	transmembrane	transmembrane	NN
cord-322516-wekvet6f	303	32	domain	domain	NN
cord-322516-wekvet6f	303	33	Characterization	characterization	NN
cord-322516-wekvet6f	303	34	of	of	IN
cord-322516-wekvet6f	303	35	a	a	DT
cord-322516-wekvet6f	303	36	ceramide	ceramide	NN
cord-322516-wekvet6f	303	37	-	-	HYPH
cord-322516-wekvet6f	303	38	activated	activate	VBN
cord-322516-wekvet6f	303	39	protein	protein	NN
cord-322516-wekvet6f	303	40	kinase	kinase	NN
cord-322516-wekvet6f	303	41	:	:	:
cord-322516-wekvet6f	303	42	stimulation	stimulation	NN
cord-322516-wekvet6f	303	43	by	by	IN
cord-322516-wekvet6f	303	44	tumor	tumor	NN
cord-322516-wekvet6f	303	45	necrosis	necrosis	NN
cord-322516-wekvet6f	303	46	factor	factor	NN
cord-322516-wekvet6f	304	1	␣	␣	NNP
cord-322516-wekvet6f	304	2	Inhibition	Inhibition	NNP
cord-322516-wekvet6f	304	3	of	of	IN
cord-322516-wekvet6f	304	4	serine	serine	JJ
cord-322516-wekvet6f	304	5	palmitoyltransferase	palmitoyltransferase	NN
cord-322516-wekvet6f	304	6	in	in	IN
cord-322516-wekvet6f	304	7	vitro	vitro	FW
cord-322516-wekvet6f	304	8	and	and	CC
cord-322516-wekvet6f	304	9	long	long	JJ
cord-322516-wekvet6f	304	10	-	-	HYPH
cord-322516-wekvet6f	304	11	chain	chain	NN
cord-322516-wekvet6f	304	12	base	base	NN
cord-322516-wekvet6f	304	13	biosynthesis	biosynthesis	NN
cord-322516-wekvet6f	304	14	in	in	IN
cord-322516-wekvet6f	304	15	intact	intact	JJ
cord-322516-wekvet6f	304	16	Chinese	chinese	JJ
cord-322516-wekvet6f	304	17	hamster	hamster	NN
cord-322516-wekvet6f	304	18	ovary	ovary	NN
cord-322516-wekvet6f	304	19	cells	cell	NNS
cord-322516-wekvet6f	304	20	by	by	IN
cord-322516-wekvet6f	304	21	␤	␤	CD
cord-322516-wekvet6f	304	22	-chloroalanine	-chloroalanine	CD
cord-322516-wekvet6f	305	1	The	the	DT
cord-322516-wekvet6f	305	2	Golgi	Golgi	NNP
cord-322516-wekvet6f	305	3	complex	complex	NN
cord-322516-wekvet6f	305	4	:	:	:
cord-322516-wekvet6f	306	1	in	in	IN
cord-322516-wekvet6f	306	2	vitro	vitro	FW
cord-322516-wekvet6f	306	3	veritas	veritas	FW
cord-322516-wekvet6f	306	4	?	?	.
cord-322516-wekvet6f	307	1	Biosynthesis	Biosynthesis	NNP
cord-322516-wekvet6f	307	2	of	of	IN
cord-322516-wekvet6f	307	3	long	long	JJ
cord-322516-wekvet6f	307	4	-	-	HYPH
cord-322516-wekvet6f	307	5	chain	chain	NN
cord-322516-wekvet6f	307	6	(	(	-LRB-
cord-322516-wekvet6f	307	7	sphingoid	sphingoid	NNP
cord-322516-wekvet6f	307	8	)	)	-RRB-
cord-322516-wekvet6f	307	9	bases	basis	NNS
cord-322516-wekvet6f	307	10	from	from	IN
cord-322516-wekvet6f	307	11	serine	serine	NN
cord-322516-wekvet6f	307	12	by	by	IN
cord-322516-wekvet6f	307	13	LM	LM	NNP
cord-322516-wekvet6f	307	14	cells	cell	NNS
cord-322516-wekvet6f	307	15	.	.	.
cord-322516-wekvet6f	308	1	Evidence	evidence	NN
cord-322516-wekvet6f	308	2	for	for	IN
cord-322516-wekvet6f	308	3	introduction	introduction	NN
cord-322516-wekvet6f	308	4	of	of	IN
cord-322516-wekvet6f	308	5	the	the	DT
cord-322516-wekvet6f	308	6	4-trans	4-trans	CD
cord-322516-wekvet6f	308	7	-	-	HYPH
cord-322516-wekvet6f	308	8	double	double	JJ
cord-322516-wekvet6f	308	9	bond	bond	NN
cord-322516-wekvet6f	308	10	after	after	IN
cord-322516-wekvet6f	308	11	de	de	NNP
cord-322516-wekvet6f	308	12	novo	novo	NNP
cord-322516-wekvet6f	308	13	biosynthesis	biosynthesis	NNP
cord-322516-wekvet6f	308	14	of	of	IN
cord-322516-wekvet6f	308	15	N	N	NNP
cord-322516-wekvet6f	308	16	-	-	HYPH
cord-322516-wekvet6f	308	17	acylsphinganines	acylsphinganine	NNS
cord-322516-wekvet6f	308	18	Isolation	Isolation	NNP
cord-322516-wekvet6f	308	19	,	,	,
cord-322516-wekvet6f	308	20	characterization	characterization	NN
cord-322516-wekvet6f	308	21	and	and	CC
cord-322516-wekvet6f	308	22	expression	expression	NN
cord-322516-wekvet6f	308	23	of	of	IN
cord-322516-wekvet6f	308	24	cDNAs	cdna	NNS
cord-322516-wekvet6f	308	25	encoding	encode	VBG
cord-322516-wekvet6f	308	26	murine	murine	JJ
cord-322516-wekvet6f	308	27	␣	␣	NNP
cord-322516-wekvet6f	308	28	-mannosidase	-mannosidase	NNP
cord-322516-wekvet6f	308	29	II	II	NNP
cord-322516-wekvet6f	308	30	,	,	,
cord-322516-wekvet6f	308	31	a	a	DT
cord-322516-wekvet6f	308	32	Golgi	Golgi	NNP
cord-322516-wekvet6f	308	33	enzyme	enzyme	NN
cord-322516-wekvet6f	308	34	that	that	WDT
cord-322516-wekvet6f	308	35	controls	control	VBZ
cord-322516-wekvet6f	308	36	conversion	conversion	NN
cord-322516-wekvet6f	308	37	of	of	IN
cord-322516-wekvet6f	308	38	high	high	JJ
cord-322516-wekvet6f	308	39	mannose	mannose	NN
cord-322516-wekvet6f	308	40	to	to	IN
cord-322516-wekvet6f	308	41	complex	complex	JJ
cord-322516-wekvet6f	308	42	N	n	CD
cord-322516-wekvet6f	308	43	-	-	HYPH
cord-322516-wekvet6f	308	44	glycans	glycan	NNS
cord-322516-wekvet6f	309	1	A	a	DT
cord-322516-wekvet6f	309	2	C	c	NN
cord-322516-wekvet6f	309	3	-	-	HYPH
cord-322516-wekvet6f	309	4	terminal	terminal	NN
cord-322516-wekvet6f	309	5	signal	signal	NN
cord-322516-wekvet6f	309	6	prevents	prevent	VBZ
cord-322516-wekvet6f	309	7	secretion	secretion	NN
cord-322516-wekvet6f	309	8	of	of	IN
cord-322516-wekvet6f	309	9	luminal	luminal	JJ
cord-322516-wekvet6f	309	10	ER	ER	NNP
cord-322516-wekvet6f	309	11	proteins	protein	NNS
cord-322516-wekvet6f	309	12	Retention	Retention	NNP
cord-322516-wekvet6f	309	13	and	and	CC
cord-322516-wekvet6f	309	14	retrieval	retrieval	NN
cord-322516-wekvet6f	309	15	in	in	IN
cord-322516-wekvet6f	309	16	the	the	DT
cord-322516-wekvet6f	309	17	endoplasmic	endoplasmic	NN
cord-322516-wekvet6f	309	18	reticulum	reticulum	NN
cord-322516-wekvet6f	309	19	and	and	CC
cord-322516-wekvet6f	309	20	Golgi	Golgi	NNP
cord-322516-wekvet6f	309	21	apparatus	apparatus	NN
cord-322516-wekvet6f	309	22	␤	␤	NNP
cord-322516-wekvet6f	309	23	-COP	-cop	NN
cord-322516-wekvet6f	309	24	localizes	localize	VBZ
cord-322516-wekvet6f	309	25	mainly	mainly	RB
cord-322516-wekvet6f	309	26	to	to	IN
cord-322516-wekvet6f	309	27	the	the	DT
cord-322516-wekvet6f	309	28	cis	cis	NNP
cord-322516-wekvet6f	309	29	-	-	HYPH
cord-322516-wekvet6f	309	30	Golgi	Golgi	NNP
cord-322516-wekvet6f	309	31	side	side	NN
cord-322516-wekvet6f	309	32	in	in	IN
cord-322516-wekvet6f	309	33	exocrine	exocrine	JJ
cord-322516-wekvet6f	309	34	pancrease	pancrease	NN
cord-322516-wekvet6f	309	35	Use	Use	NNP
cord-322516-wekvet6f	309	36	of	of	IN
cord-322516-wekvet6f	309	37	fluorescent	fluorescent	JJ
cord-322516-wekvet6f	309	38	analogs	analog	NNS
cord-322516-wekvet6f	309	39	of	of	IN
cord-322516-wekvet6f	309	40	ceramide	ceramide	NN
cord-322516-wekvet6f	309	41	to	to	TO
cord-322516-wekvet6f	309	42	study	study	VB
cord-322516-wekvet6f	309	43	the	the	DT
cord-322516-wekvet6f	309	44	Golgi	Golgi	NNP
cord-322516-wekvet6f	309	45	apparatus	apparatus	NN
cord-322516-wekvet6f	309	46	of	of	IN
cord-322516-wekvet6f	309	47	animal	animal	NN
cord-322516-wekvet6f	309	48	cells	cell	NNS
cord-322516-wekvet6f	309	49	Molecular	molecular	JJ
cord-322516-wekvet6f	309	50	trapping	trap	VBG
cord-322516-wekvet6f	309	51	of	of	IN
cord-322516-wekvet6f	309	52	a	a	DT
cord-322516-wekvet6f	309	53	fluorescent	fluorescent	JJ
cord-322516-wekvet6f	309	54	ceramide	ceramide	NN
cord-322516-wekvet6f	309	55	analogue	analogue	NN
cord-322516-wekvet6f	309	56	at	at	IN
cord-322516-wekvet6f	309	57	the	the	DT
cord-322516-wekvet6f	309	58	Golgi	Golgi	NNP
cord-322516-wekvet6f	309	59	apparatus	apparatus	NN
cord-322516-wekvet6f	309	60	of	of	IN
cord-322516-wekvet6f	309	61	fixed	fix	VBN
cord-322516-wekvet6f	309	62	cells	cell	NNS
cord-322516-wekvet6f	309	63	:	:	:
cord-322516-wekvet6f	309	64	interaction	interaction	NN
cord-322516-wekvet6f	309	65	with	with	IN
cord-322516-wekvet6f	309	66	endogenous	endogenous	JJ
cord-322516-wekvet6f	309	67	lipids	lipid	NNS
cord-322516-wekvet6f	309	68	provides	provide	VBZ
cord-322516-wekvet6f	309	69	a	a	DT
cord-322516-wekvet6f	309	70	trans	trans	JJ
cord-322516-wekvet6f	309	71	-	-	JJ
cord-322516-wekvet6f	309	72	Golgi	Golgi	NNP
cord-322516-wekvet6f	309	73	marker	marker	NN
cord-322516-wekvet6f	309	74	for	for	IN
cord-322516-wekvet6f	309	75	both	both	DT
cord-322516-wekvet6f	309	76	light	light	NN
cord-322516-wekvet6f	309	77	and	and	CC
cord-322516-wekvet6f	309	78	electron	electron	NN
cord-322516-wekvet6f	309	79	microscopy	microscopy	NN
cord-322516-wekvet6f	309	80	Elevation	elevation	NN
cord-322516-wekvet6f	309	81	of	of	IN
cord-322516-wekvet6f	309	82	ceramide	ceramide	NN
cord-322516-wekvet6f	309	83	within	within	IN
cord-322516-wekvet6f	309	84	distal	distal	JJ
cord-322516-wekvet6f	309	85	neurites	neurite	NNS
cord-322516-wekvet6f	309	86	inhibits	inhibit	VBZ
cord-322516-wekvet6f	309	87	neurite	neurite	NN
cord-322516-wekvet6f	309	88	growth	growth	NN
cord-322516-wekvet6f	309	89	in	in	IN
cord-322516-wekvet6f	309	90	cultured	cultured	JJ
cord-322516-wekvet6f	309	91	rat	rat	NN
cord-322516-wekvet6f	309	92	sympathetic	sympathetic	JJ
cord-322516-wekvet6f	309	93	neurons	neuron	NNS
cord-322516-wekvet6f	309	94	Cell	Cell	NNP
cord-322516-wekvet6f	309	95	cycle	cycle	NN
cord-322516-wekvet6f	309	96	arrest	arrest	NN
cord-322516-wekvet6f	309	97	induced	induce	VBN
cord-322516-wekvet6f	309	98	by	by	IN
cord-322516-wekvet6f	309	99	an	an	DT
cord-322516-wekvet6f	309	100	inhibitor	inhibitor	NN
cord-322516-wekvet6f	309	101	of	of	IN
cord-322516-wekvet6f	309	102	glucosylceramide	glucosylceramide	JJ
cord-322516-wekvet6f	309	103	synthase	synthase	NN
cord-322516-wekvet6f	309	104	.	.	.
cord-322516-wekvet6f	310	1	Correlation	correlation	NN
cord-322516-wekvet6f	310	2	with	with	IN
cord-322516-wekvet6f	310	3	cyclin	cyclin	NN
cord-322516-wekvet6f	310	4	-	-	HYPH
cord-322516-wekvet6f	310	5	independent	independent	JJ
cord-322516-wekvet6f	310	6	kinases	kinase	NNS
cord-322516-wekvet6f	310	7	Inhibition	Inhibition	NNP
cord-322516-wekvet6f	310	8	of	of	IN
cord-322516-wekvet6f	310	9	glycoprotein	glycoprotein	NN
cord-322516-wekvet6f	310	10	traffic	traffic	NN
cord-322516-wekvet6f	310	11	through	through	IN
cord-322516-wekvet6f	310	12	the	the	DT
cord-322516-wekvet6f	310	13	secretory	secretory	JJ
cord-322516-wekvet6f	310	14	pathway	pathway	NN
cord-322516-wekvet6f	310	15	by	by	IN
cord-322516-wekvet6f	310	16	ceramide	ceramide	NN
cord-322516-wekvet6f	310	17	Effects	effect	NNS
cord-322516-wekvet6f	310	18	of	of	IN
cord-322516-wekvet6f	310	19	a	a	DT
cord-322516-wekvet6f	310	20	sphingolipid	sphingolipid	NN
cord-322516-wekvet6f	310	21	synthesis	synthesis	NN
cord-322516-wekvet6f	310	22	inhibitor	inhibitor	NN
cord-322516-wekvet6f	310	23	on	on	IN
cord-322516-wekvet6f	310	24	membrane	membrane	NN
cord-322516-wekvet6f	310	25	transport	transport	NN
cord-322516-wekvet6f	310	26	through	through	IN
cord-322516-wekvet6f	310	27	the	the	DT
cord-322516-wekvet6f	310	28	secretory	secretory	JJ
cord-322516-wekvet6f	310	29	pathway	pathway	NN
cord-322516-wekvet6f	310	30	ERGIC-53	ERGIC-53	NNP
cord-322516-wekvet6f	310	31	,	,	,
cord-322516-wekvet6f	310	32	a	a	DT
cord-322516-wekvet6f	310	33	membrane	membrane	NN
cord-322516-wekvet6f	310	34	protein	protein	NN
cord-322516-wekvet6f	310	35	of	of	IN
cord-322516-wekvet6f	310	36	the	the	DT
cord-322516-wekvet6f	310	37	ER	ER	NNP
cord-322516-wekvet6f	310	38	-	-	HYPH
cord-322516-wekvet6f	310	39	Golgi	Golgi	NNP
cord-322516-wekvet6f	310	40	intermediate	intermediate	JJ
cord-322516-wekvet6f	310	41	compartment	compartment	NN
cord-322516-wekvet6f	310	42	,	,	,
cord-322516-wekvet6f	310	43	carries	carry	VBZ
cord-322516-wekvet6f	310	44	an	an	DT
cord-322516-wekvet6f	310	45	ER	ER	NNP
cord-322516-wekvet6f	310	46	retention	retention	NN
cord-322516-wekvet6f	310	47	motif	motif	NN
cord-322516-wekvet6f	310	48	Identification	identification	NN
cord-322516-wekvet6f	310	49	,	,	,
cord-322516-wekvet6f	310	50	by	by	IN
cord-322516-wekvet6f	310	51	a	a	DT
cord-322516-wekvet6f	310	52	monoclonal	monoclonal	JJ
cord-322516-wekvet6f	310	53	antibody	antibody	NN
cord-322516-wekvet6f	310	54	,	,	,
cord-322516-wekvet6f	310	55	of	of	IN
cord-322516-wekvet6f	310	56	a	a	DT
cord-322516-wekvet6f	310	57	53-kD	53-kd	CD
cord-322516-wekvet6f	310	58	protein	protein	NN
cord-322516-wekvet6f	310	59	associated	associate	VBN
cord-322516-wekvet6f	310	60	with	with	IN
cord-322516-wekvet6f	310	61	a	a	DT
cord-322516-wekvet6f	310	62	tubulovesicular	tubulovesicular	NNP
cord-322516-wekvet6f	310	63	compartment	compartment	NN
cord-322516-wekvet6f	310	64	at	at	IN
cord-322516-wekvet6f	310	65	the	the	DT
cord-322516-wekvet6f	310	66	cis	cis	NNP
cord-322516-wekvet6f	310	67	-	-	HYPH
cord-322516-wekvet6f	310	68	side	side	NN
cord-322516-wekvet6f	310	69	of	of	IN
cord-322516-wekvet6f	310	70	the	the	DT
cord-322516-wekvet6f	310	71	Golgi	Golgi	NNP
cord-322516-wekvet6f	310	72	apparatus	apparatus	NN
cord-322516-wekvet6f	310	73	Modulation	modulation	NN
cord-322516-wekvet6f	310	74	of	of	IN
cord-322516-wekvet6f	310	75	renal	renal	JJ
cord-322516-wekvet6f	310	76	epithelial	epithelial	JJ
cord-322516-wekvet6f	310	77	cell	cell	NN
cord-322516-wekvet6f	310	78	growth	growth	NN
cord-322516-wekvet6f	310	79	by	by	IN
cord-322516-wekvet6f	310	80	glucosylceramide	glucosylceramide	NNP
cord-322516-wekvet6f	310	81	.	.	.
cord-322516-wekvet6f	311	1	Association	Association	NNP
cord-322516-wekvet6f	311	2	with	with	IN
cord-322516-wekvet6f	311	3	protein	protein	NN
cord-322516-wekvet6f	311	4	kinase	kinase	NN
cord-322516-wekvet6f	311	5	C	C	NNP
cord-322516-wekvet6f	311	6	,	,	,
cord-322516-wekvet6f	311	7	sphingosine	sphingosine	NNP
cord-322516-wekvet6f	311	8	,	,	,
cord-322516-wekvet6f	311	9	and	and	CC
cord-322516-wekvet6f	311	10	diacylglycerol	diacylglycerol	NNP
cord-322516-wekvet6f	311	11	Assembly	Assembly	NNP
cord-322516-wekvet6f	311	12	of	of	IN
cord-322516-wekvet6f	311	13	vaccinia	vaccinia	NN
cord-322516-wekvet6f	311	14	virus	virus	NN
cord-322516-wekvet6f	311	15	:	:	:
cord-322516-wekvet6f	311	16	role	role	NN
cord-322516-wekvet6f	311	17	of	of	IN
cord-322516-wekvet6f	311	18	the	the	DT
cord-322516-wekvet6f	311	19	intermediate	intermediate	JJ
cord-322516-wekvet6f	311	20	compartment	compartment	NN
cord-322516-wekvet6f	311	21	between	between	IN
cord-322516-wekvet6f	311	22	the	the	DT
cord-322516-wekvet6f	311	23	endoplasmic	endoplasmic	NN
cord-322516-wekvet6f	311	24	reticulum	reticulum	NN
cord-322516-wekvet6f	311	25	and	and	CC
cord-322516-wekvet6f	311	26	the	the	DT
cord-322516-wekvet6f	311	27	Golgi	Golgi	NNP
cord-322516-wekvet6f	311	28	stacks	stack	VBZ
cord-322516-wekvet6f	311	29	A	a	DT
cord-322516-wekvet6f	311	30	Golgi	Golgi	NNP
cord-322516-wekvet6f	311	31	retention	retention	NN
cord-322516-wekvet6f	311	32	signal	signal	NN
cord-322516-wekvet6f	311	33	in	in	IN
cord-322516-wekvet6f	311	34	a	a	DT
cord-322516-wekvet6f	311	35	membrane	membrane	NN
cord-322516-wekvet6f	311	36	-	-	HYPH
cord-322516-wekvet6f	311	37	spanning	span	VBG
cord-322516-wekvet6f	311	38	domain	domain	NN
cord-322516-wekvet6f	311	39	of	of	IN
cord-322516-wekvet6f	311	40	coronavirus	coronavirus	NN
cord-322516-wekvet6f	311	41	E1	e1	NN
cord-322516-wekvet6f	311	42	protein	protein	NN
cord-322516-wekvet6f	311	43	Effect	effect	NN
cord-322516-wekvet6f	311	44	of	of	IN
cord-322516-wekvet6f	311	45	an	an	DT
cord-322516-wekvet6f	311	46	inhibitor	inhibitor	NN
cord-322516-wekvet6f	311	47	of	of	IN
cord-322516-wekvet6f	311	48	glucosylceramide	glucosylceramide	JJ
cord-322516-wekvet6f	311	49	synthesis	synthesis	NN
cord-322516-wekvet6f	311	50	on	on	IN
cord-322516-wekvet6f	311	51	cultured	cultured	JJ
cord-322516-wekvet6f	311	52	rabbit	rabbit	NN
cord-322516-wekvet6f	311	53	skin	skin	NN
cord-322516-wekvet6f	311	54	fibroblasts	fibroblast	NNS
cord-322516-wekvet6f	311	55	Transport	transport	NN
cord-322516-wekvet6f	311	56	and	and	CC
cord-322516-wekvet6f	311	57	sorting	sorting	NN
cord-322516-wekvet6f	311	58	of	of	IN
cord-322516-wekvet6f	311	59	membrane	membrane	NN
cord-322516-wekvet6f	311	60	lipids	lipid	NNS
cord-322516-wekvet6f	311	61	Cell	cell	NN
cord-322516-wekvet6f	311	62	type	type	NN
cord-322516-wekvet6f	311	63	-	-	HYPH
cord-322516-wekvet6f	311	64	dependent	dependent	JJ
cord-322516-wekvet6f	311	65	variations	variation	NNS
cord-322516-wekvet6f	311	66	in	in	IN
cord-322516-wekvet6f	311	67	the	the	DT
cord-322516-wekvet6f	311	68	subcellular	subcellular	JJ
cord-322516-wekvet6f	311	69	distribution	distribution	NN
cord-322516-wekvet6f	311	70	of	of	IN
cord-322516-wekvet6f	311	71	␣	␣	NNP
cord-322516-wekvet6f	312	1	-mannosidase	-mannosidase	:
cord-322516-wekvet6f	313	1	I	-PRON-	PRP
cord-322516-wekvet6f	313	2	and	and	CC
cord-322516-wekvet6f	313	3	II	II	NNP
cord-322516-wekvet6f	313	4	Analogs	Analogs	NNP
cord-322516-wekvet6f	313	5	of	of	IN
cord-322516-wekvet6f	313	6	ceramide	ceramide	NN
cord-322516-wekvet6f	313	7	that	that	WDT
cord-322516-wekvet6f	313	8	inhibit	inhibit	VBP
cord-322516-wekvet6f	313	9	glucocerebroside	glucocerebroside	NN
cord-322516-wekvet6f	313	10	synthetase	synthetase	NN
cord-322516-wekvet6f	313	11	in	in	IN
cord-322516-wekvet6f	313	12	mouse	mouse	NN
cord-322516-wekvet6f	313	13	brain	brain	NN
cord-322516-wekvet6f	313	14	Inhibition	inhibition	NN
cord-322516-wekvet6f	313	15	of	of	IN
cord-322516-wekvet6f	313	16	sphingolipid	sphingolipid	NNP
cord-322516-wekvet6f	313	17	biosynthesis	biosynthesis	NN
cord-322516-wekvet6f	313	18	by	by	IN
cord-322516-wekvet6f	313	19	fumonisins	fumonisin	NNS
cord-322516-wekvet6f	313	20	:	:	:
cord-322516-wekvet6f	313	21	implications	implication	NNS
cord-322516-wekvet6f	313	22	for	for	IN
cord-322516-wekvet6f	313	23	diseases	disease	NNS
cord-322516-wekvet6f	313	24	associated	associate	VBN
cord-322516-wekvet6f	313	25	with	with	IN
cord-322516-wekvet6f	313	26	Fusarium	Fusarium	NNP
cord-322516-wekvet6f	313	27	moniliforme	moniliforme	NNP
cord-322516-wekvet6f	313	28	Oligomerization	Oligomerization	NNP
cord-322516-wekvet6f	313	29	of	of	IN
cord-322516-wekvet6f	313	30	a	a	DT
cord-322516-wekvet6f	313	31	membrane	membrane	NN
cord-322516-wekvet6f	313	32	protein	protein	NN
cord-322516-wekvet6f	313	33	correlates	correlate	VBZ
cord-322516-wekvet6f	313	34	with	with	IN
cord-322516-wekvet6f	313	35	its	-PRON-	PRP$
cord-322516-wekvet6f	313	36	retention	retention	NN
cord-322516-wekvet6f	313	37	in	in	IN
cord-322516-wekvet6f	313	38	the	the	DT
cord-322516-wekvet6f	313	39	Golgi	Golgi	NNP
cord-322516-wekvet6f	313	40	complex	complex	JJ
cord-322516-wekvet6f	313	41	Role	role	NN
cord-322516-wekvet6f	313	42	of	of	IN
cord-322516-wekvet6f	313	43	ceramide	ceramide	NN
cord-322516-wekvet6f	313	44	-	-	HYPH
cord-322516-wekvet6f	313	45	activated	activate	VBN
cord-322516-wekvet6f	313	46	protein	protein	NN
cord-322516-wekvet6f	313	47	phosphatase	phosphatase	NN
cord-322516-wekvet6f	313	48	in	in	IN
cord-322516-wekvet6f	313	49	ceramide	ceramide	NN
cord-322516-wekvet6f	313	50	-	-	HYPH
cord-322516-wekvet6f	313	51	mediated	mediate	VBN
cord-322516-wekvet6f	313	52	signal	signal	NN
cord-322516-wekvet6f	313	53	transduction	transduction	NN
cord-322516-wekvet6f	314	1	We	-PRON-	PRP
cord-322516-wekvet6f	314	2	thank	thank	VBP
cord-322516-wekvet6f	314	3	Drs	Drs	NNP
cord-322516-wekvet6f	314	4	.	.	.
cord-322516-wekvet6f	315	1	E.	E.	NNP
cord-322516-wekvet6f	315	2	Cluett	Cluett	NNP
cord-322516-wekvet6f	315	3	,	,	,
cord-322516-wekvet6f	315	4	D.	D.	NNP
cord-322516-wekvet6f	315	5	Raben	Raben	NNP
cord-322516-wekvet6f	315	6	,	,	,
cord-322516-wekvet6f	315	7	and	and	CC
cord-322516-wekvet6f	315	8	A.	A.	NNP
cord-322516-wekvet6f	315	9	Hubbard	Hubbard	NNP
cord-322516-wekvet6f	315	10	for	for	IN
cord-322516-wekvet6f	315	11	useful	useful	JJ
cord-322516-wekvet6f	315	12	discussions	discussion	NNS
cord-322516-wekvet6f	315	13	and	and	CC
cord-322516-wekvet6f	315	14	the	the	DT
cord-322516-wekvet6f	315	15	members	member	NNS
cord-322516-wekvet6f	315	16	of	of	IN
cord-322516-wekvet6f	315	17	the	the	DT
cord-322516-wekvet6f	315	18	Machamer	Machamer	NNP
cord-322516-wekvet6f	315	19	lab	lab	NN
cord-322516-wekvet6f	315	20	for	for	IN
cord-322516-wekvet6f	315	21	critical	critical	JJ
cord-322516-wekvet6f	315	22	reading	reading	NN
cord-322516-wekvet6f	315	23	of	of	IN
cord-322516-wekvet6f	315	24	the	the	DT
cord-322516-wekvet6f	315	25	manuscript	manuscript	NN
cord-322516-wekvet6f	315	26	.	.	.
cord-322516-wekvet6f	316	1	We	-PRON-	PRP
cord-322516-wekvet6f	316	2	also	also	RB
cord-322516-wekvet6f	316	3	thank	thank	VBP
cord-322516-wekvet6f	316	4	H.-P.	H.-P.	.
cord-322516-wekvet6f	317	1	Hauri	Hauri	NNP
cord-322516-wekvet6f	317	2	,	,	,
cord-322516-wekvet6f	317	3	M.	M.	NNP
cord-322516-wekvet6f	317	4	Farquhar	Farquhar	NNP
cord-322516-wekvet6f	317	5	,	,	,
cord-322516-wekvet6f	317	6	K.	K.	NNP
cord-322516-wekvet6f	317	7	Moremen	Moremen	NNP
cord-322516-wekvet6f	317	8	,	,	,
cord-322516-wekvet6f	317	9	and	and	CC
cord-322516-wekvet6f	317	10	J.	J.	NNP
cord-322516-wekvet6f	317	11	Lippincott	Lippincott	NNP
cord-322516-wekvet6f	317	12	-	-	HYPH
cord-322516-wekvet6f	317	13	Schwartz	Schwartz	NNP
cord-322516-wekvet6f	317	14	for	for	IN
cord-322516-wekvet6f	317	15	antibodies	antibody	NNS
cord-322516-wekvet6f	317	16	.	.	.
cord-322516-wekvet6f	318	1	This	this	DT
cord-322516-wekvet6f	318	2	work	work	NN
cord-322516-wekvet6f	318	3	was	be	VBD
cord-322516-wekvet6f	318	4	supported	support	VBN
cord-322516-wekvet6f	318	5	by	by	IN
cord-322516-wekvet6f	318	6	grant	grant	NN
cord-322516-wekvet6f	318	7	GM42522	gm42522	NN
cord-322516-wekvet6f	318	8	from	from	IN
cord-322516-wekvet6f	318	9	the	the	DT
cord-322516-wekvet6f	318	10	National	National	NNP
cord-322516-wekvet6f	318	11	Institutes	Institutes	NNPS
cord-322516-wekvet6f	318	12	of	of	IN
cord-322516-wekvet6f	318	13	Health	Health	NNP
cord-322516-wekvet6f	318	14	.	.	.
cord-322516-wekvet6f	319	1	Received	receive	VBN
cord-322516-wekvet6f	319	2	for	for	IN
cord-322516-wekvet6f	319	3	publication	publication	NN
cord-322516-wekvet6f	319	4	29	29	CD
cord-322516-wekvet6f	319	5	August	August	NNP
cord-322516-wekvet6f	319	6	1997	1997	CD
cord-322516-wekvet6f	319	7	and	and	CC
cord-322516-wekvet6f	319	8	in	in	IN
cord-322516-wekvet6f	319	9	revised	revise	VBN
cord-322516-wekvet6f	319	10	form	form	NN
cord-322516-wekvet6f	319	11	6	6	CD
cord-322516-wekvet6f	319	12	October	October	NNP
cord-322516-wekvet6f	319	13	1997.The	1997.the	CD
cord-322516-wekvet6f	319	14	Journal	Journal	NNP
cord-322516-wekvet6f	319	15	of	of	IN
cord-322516-wekvet6f	319	16	Cell	Cell	NNP
cord-322516-wekvet6f	319	17	Biology	Biology	NNP
cord-322516-wekvet6f	319	18	,	,	,
cord-322516-wekvet6f	319	19	Volume	volume	NN
cord-322516-wekvet6f	319	20	139	139	CD
cord-322516-wekvet6f	319	21	,	,	,
cord-322516-wekvet6f	319	22	1997	1997	CD