id author title date pages extension mime words sentences flesch summary cache txt cord-009962-k3opc553 Stjernquist‐Desatnik, Anna Pharyngotonsillitis 2008-12-17 .txt text/plain 5501 317 32 Acute rheumatic fever, the most serious nonsuppurative complication of beta-hemolytic group A streptococcal pharyngotonsillitis, is the leading cause of acquired heart disease among children in developing countries (5) . However, beta-hemolytic group A streptococci are amongst the most virulent human pathogens, and patients with pharyngotonsillitis caused by infection with this bacterium can be seriously affected with high fever, dysphagia and severe pain. The decline of acute rheumatic fever in the developed world may indeed be the result of routine antibiotic use for beta-hemolytic group A streptococcal pharyngotonsillitis, supporting the present principles of treatment. Penicillin V was detected in tonsillar surface fluid in a majority of patients on the first day of treatment of acute beta-hemolytic group A streptococcus pharyngotonsillitis, but despite a high concentration in serum, was rarely present on the 10th day or in healthy, treated subjects (81) . ./cache/cord-009962-k3opc553.txt ./txt/cord-009962-k3opc553.txt