id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261163-n9tp9nx7	Ko, Jae-Hoon	Serologic responses of 42 MERS-coronavirus-infected patients according to the disease severity	2017-10-31		.txt	text/plain	3140	144	44	Abstract We evaluated serologic response of 42 Middle East respiratory syndrome coronavirus (MERS-CoV)-infected patients according to 4 severity groups: asymptomatic infection (Group 0), symptomatic infection without pneumonia (Group 1), pneumonia without respiratory failure (Group 2), and pneumonia progressing to respiratory failure (Group 3). Based on these findings, we evaluated serologic response of 42 MERS-CoV-infected patients according to the disease severity to investigate potential role of serodiagnostic parameters as prognostic markers. Although different seroconversion rates depending on disease severity can be inferred from previous serologic investigation (Min et al., 2016) , the number of evaluated MERS patients was limited to 14 and neutralization testing was not performed. Serologic response was delayed in Group 3 patients, and negative seroconversion by the third week of illness was associated with fatal outcome among patients with MERS pneumonia (HR 27.83, 95% CI 2.76-280.21, P = 0.005).	./cache/cord-261163-n9tp9nx7.txt	./txt/cord-261163-n9tp9nx7.txt