id author title date pages extension mime words sentences flesch summary cache txt cord-274545-r03g7w0b Ayele Mega, Teshale The Outcome of Hydroxychloroquine in Patients Treated for COVID-19: Systematic Review and Meta-Analysis 2020-10-13 .txt text/plain 6277 376 56 In this open-label non-randomized clinical trial, a total of 20 patients were treated with HCQ at a dose of 200 mg three times daily for 10 days, and the data showed a significant reduction in viral carriage at day 6 post-inclusion compared to controls (70.0% clearance by day 6 vs. e outcomes assessed with double-arm studies include virologic efficacy [8, 20, 21] , clinical efficacy (mortality [4, 8, 13, 14, 30, 31] and disease progression [4, 8, 13, 14, 22, 31, 32] ), safety (risk of adverse effects) [8, [20] [21] [22] , and tolerability and QT prolongation [14, 26, 34] . e data from four controlled clinical trials [8, [20] [21] [22] of 278 COVID-19 patients (141 HCQ and 137 from the non-HCQ group) were included to assess overall adverse effects (except QTc prolongation) among HCQ-exposed patients. ./cache/cord-274545-r03g7w0b.txt ./txt/cord-274545-r03g7w0b.txt