id sid tid token lemma pos cord-261186-4p1cwb2e 1 1 key key JJ cord-261186-4p1cwb2e 1 2 : : : cord-261186-4p1cwb2e 1 3 cord-261186 cord-261186 NNP cord-261186-4p1cwb2e 1 4 - - HYPH cord-261186-4p1cwb2e 1 5 4p1cwb2e 4p1cwb2e CD cord-261186-4p1cwb2e 1 6 authors author NNS cord-261186-4p1cwb2e 1 7 : : : cord-261186-4p1cwb2e 1 8 Guzman Guzman NNP cord-261186-4p1cwb2e 1 9 - - HYPH cord-261186-4p1cwb2e 1 10 Prado Prado NNP cord-261186-4p1cwb2e 1 11 , , , cord-261186-4p1cwb2e 2 1 Yuli Yuli NNP cord-261186-4p1cwb2e 2 2 title title NN cord-261186-4p1cwb2e 2 3 : : : cord-261186-4p1cwb2e 2 4 Recent recent JJ cord-261186-4p1cwb2e 2 5 findings finding NNS cord-261186-4p1cwb2e 2 6 on on IN cord-261186-4p1cwb2e 2 7 cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 2 8 safety safety NN cord-261186-4p1cwb2e 2 9 with with IN cord-261186-4p1cwb2e 2 10 the the DT cord-261186-4p1cwb2e 2 11 use use NN cord-261186-4p1cwb2e 2 12 of of IN cord-261186-4p1cwb2e 2 13 chloroquine chloroquine NN cord-261186-4p1cwb2e 2 14 and and CC cord-261186-4p1cwb2e 2 15 hydroxychloroquine hydroxychloroquine NN cord-261186-4p1cwb2e 2 16 for for IN cord-261186-4p1cwb2e 2 17 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 2 18 . . . cord-261186-4p1cwb2e 2 19 date date NN cord-261186-4p1cwb2e 2 20 : : : cord-261186-4p1cwb2e 2 21 2020 2020 CD cord-261186-4p1cwb2e 2 22 - - HYPH cord-261186-4p1cwb2e 2 23 06 06 CD cord-261186-4p1cwb2e 2 24 - - HYPH cord-261186-4p1cwb2e 2 25 09 09 CD cord-261186-4p1cwb2e 2 26 journal journal NN cord-261186-4p1cwb2e 2 27 : : : cord-261186-4p1cwb2e 3 1 Am be VBP cord-261186-4p1cwb2e 3 2 J J NNP cord-261186-4p1cwb2e 3 3 Cardiol Cardiol NNP cord-261186-4p1cwb2e 4 1 DOI DOI NNP cord-261186-4p1cwb2e 5 1 : : : cord-261186-4p1cwb2e 5 2 10.1016 10.1016 CD cord-261186-4p1cwb2e 5 3 / / SYM cord-261186-4p1cwb2e 5 4 j.amjcard.2020.06.003 j.amjcard.2020.06.003 NN cord-261186-4p1cwb2e 5 5 sha sha NNP cord-261186-4p1cwb2e 5 6 : : : cord-261186-4p1cwb2e 6 1 1b85df584f5cf05e01077673229b523c18ed1f9d 1b85df584f5cf05e01077673229b523c18ed1f9d CD cord-261186-4p1cwb2e 6 2 doc_id doc_id CD cord-261186-4p1cwb2e 6 3 : : : cord-261186-4p1cwb2e 6 4 261186 261186 CD cord-261186-4p1cwb2e 6 5 cord_uid cord_uid NNS cord-261186-4p1cwb2e 6 6 : : : cord-261186-4p1cwb2e 7 1 4p1cwb2e 4p1cwb2e CD cord-261186-4p1cwb2e 7 2 nan nan NNP cord-261186-4p1cwb2e 7 3 and and CC cord-261186-4p1cwb2e 7 4 found find VBD cord-261186-4p1cwb2e 7 5 no no DT cord-261186-4p1cwb2e 7 6 significant significant JJ cord-261186-4p1cwb2e 7 7 differences difference NNS cord-261186-4p1cwb2e 7 8 in in IN cord-261186-4p1cwb2e 7 9 the the DT cord-261186-4p1cwb2e 7 10 likelihood likelihood NN cord-261186-4p1cwb2e 7 11 of of IN cord-261186-4p1cwb2e 7 12 abnormal abnormal JJ cord-261186-4p1cwb2e 7 13 electrocardiogram electrocardiogram NN cord-261186-4p1cwb2e 7 14 findings finding NNS cord-261186-4p1cwb2e 7 15 ( ( -LRB- cord-261186-4p1cwb2e 7 16 defined define VBN cord-261186-4p1cwb2e 7 17 as as IN cord-261186-4p1cwb2e 7 18 arrhythmia arrhythmia NN cord-261186-4p1cwb2e 7 19 or or CC cord-261186-4p1cwb2e 7 20 prolonged prolong VBN cord-261186-4p1cwb2e 7 21 QT qt NN cord-261186-4p1cwb2e 7 22 interval interval NN cord-261186-4p1cwb2e 7 23 ) ) -RRB- cord-261186-4p1cwb2e 7 24 between between IN cord-261186-4p1cwb2e 7 25 groups group NNS cord-261186-4p1cwb2e 7 26 , , , cord-261186-4p1cwb2e 7 27 however however RB cord-261186-4p1cwb2e 7 28 , , , cord-261186-4p1cwb2e 7 29 the the DT cord-261186-4p1cwb2e 7 30 researchers researcher NNS cord-261186-4p1cwb2e 7 31 highlight highlight VBP cord-261186-4p1cwb2e 7 32 that that IN cord-261186-4p1cwb2e 7 33 cardiac cardiac JJ cord-261186-4p1cwb2e 7 34 arrest arrest NN cord-261186-4p1cwb2e 7 35 was be VBD cord-261186-4p1cwb2e 7 36 more more RBR cord-261186-4p1cwb2e 7 37 likely likely JJ cord-261186-4p1cwb2e 7 38 in in IN cord-261186-4p1cwb2e 7 39 the the DT cord-261186-4p1cwb2e 7 40 group group NN cord-261186-4p1cwb2e 7 41 treated treat VBN cord-261186-4p1cwb2e 7 42 with with IN cord-261186-4p1cwb2e 7 43 HCQ HCQ NNP cord-261186-4p1cwb2e 7 44 plus plus CC cord-261186-4p1cwb2e 7 45 AZ AZ NNP cord-261186-4p1cwb2e 7 46 ( ( -LRB- cord-261186-4p1cwb2e 7 47 adjusted adjust VBN cord-261186-4p1cwb2e 7 48 OR or CC cord-261186-4p1cwb2e 7 49 2.13 2.13 CD cord-261186-4p1cwb2e 7 50 ; ; : cord-261186-4p1cwb2e 7 51 95 95 CD cord-261186-4p1cwb2e 7 52 % % NN cord-261186-4p1cwb2e 7 53 CI CI NNP cord-261186-4p1cwb2e 7 54 1.12 1.12 CD cord-261186-4p1cwb2e 7 55 -4.05 -4.05 CD cord-261186-4p1cwb2e 7 56 ) ) -RRB- cord-261186-4p1cwb2e 7 57 . . . cord-261186-4p1cwb2e 8 1 No no DT cord-261186-4p1cwb2e 8 2 significant significant JJ cord-261186-4p1cwb2e 8 3 differences difference NNS cord-261186-4p1cwb2e 8 4 in in IN cord-261186-4p1cwb2e 8 5 in in IN cord-261186-4p1cwb2e 8 6 - - HYPH cord-261186-4p1cwb2e 8 7 hospital hospital NN cord-261186-4p1cwb2e 8 8 mortality mortality NN cord-261186-4p1cwb2e 8 9 were be VBD cord-261186-4p1cwb2e 8 10 found find VBN cord-261186-4p1cwb2e 8 11 . . . cord-261186-4p1cwb2e 9 1 In in IN cord-261186-4p1cwb2e 9 2 order order NN cord-261186-4p1cwb2e 9 3 to to TO cord-261186-4p1cwb2e 9 4 elucidate elucidate VB cord-261186-4p1cwb2e 9 5 if if IN cord-261186-4p1cwb2e 9 6 the the DT cord-261186-4p1cwb2e 9 7 finding finding NN cord-261186-4p1cwb2e 9 8 of of IN cord-261186-4p1cwb2e 9 9 cardiac cardiac JJ cord-261186-4p1cwb2e 9 10 arrest arrest NN cord-261186-4p1cwb2e 9 11 was be VBD cord-261186-4p1cwb2e 9 12 mediated mediate VBN cord-261186-4p1cwb2e 9 13 or or CC cord-261186-4p1cwb2e 9 14 not not RB cord-261186-4p1cwb2e 9 15 by by IN cord-261186-4p1cwb2e 9 16 mechanical mechanical JJ cord-261186-4p1cwb2e 9 17 ventilation ventilation NN cord-261186-4p1cwb2e 9 18 , , , cord-261186-4p1cwb2e 9 19 the the DT cord-261186-4p1cwb2e 9 20 authors author NNS cord-261186-4p1cwb2e 9 21 performed perform VBD cord-261186-4p1cwb2e 9 22 a a DT cord-261186-4p1cwb2e 9 23 stratified stratified JJ cord-261186-4p1cwb2e 9 24 analysis analysis NN cord-261186-4p1cwb2e 9 25 and and CC cord-261186-4p1cwb2e 9 26 indicated indicate VBD cord-261186-4p1cwb2e 9 27 that that IN cord-261186-4p1cwb2e 9 28 in in IN cord-261186-4p1cwb2e 9 29 the the DT cord-261186-4p1cwb2e 9 30 group group NN cord-261186-4p1cwb2e 9 31 of of IN cord-261186-4p1cwb2e 9 32 patients patient NNS cord-261186-4p1cwb2e 9 33 who who WP cord-261186-4p1cwb2e 9 34 did do VBD cord-261186-4p1cwb2e 9 35 not not RB cord-261186-4p1cwb2e 9 36 receive receive VB cord-261186-4p1cwb2e 9 37 mechanical mechanical JJ cord-261186-4p1cwb2e 9 38 ventilation ventilation NN cord-261186-4p1cwb2e 9 39 , , , cord-261186-4p1cwb2e 9 40 the the DT cord-261186-4p1cwb2e 9 41 risk risk NN cord-261186-4p1cwb2e 9 42 for for IN cord-261186-4p1cwb2e 9 43 cardiac cardiac JJ cord-261186-4p1cwb2e 9 44 arrest arrest NN cord-261186-4p1cwb2e 9 45 remained remain VBD cord-261186-4p1cwb2e 9 46 increased increase VBN cord-261186-4p1cwb2e 9 47 for for IN cord-261186-4p1cwb2e 9 48 HCQ HCQ NNP cord-261186-4p1cwb2e 9 49 alone alone RB cord-261186-4p1cwb2e 9 50 compared compare VBN cord-261186-4p1cwb2e 9 51 with with IN cord-261186-4p1cwb2e 9 52 AZ AZ NNP cord-261186-4p1cwb2e 9 53 alone alone JJ cord-261186-4p1cwb2e 9 54 ( ( -LRB- cord-261186-4p1cwb2e 9 55 adjusted adjust VBN cord-261186-4p1cwb2e 9 56 OR or CC cord-261186-4p1cwb2e 9 57 3.01 3.01 CD cord-261186-4p1cwb2e 9 58 95 95 CD cord-261186-4p1cwb2e 9 59 % % NN cord-261186-4p1cwb2e 9 60 CI CI NNP cord-261186-4p1cwb2e 9 61 1.07 1.07 CD cord-261186-4p1cwb2e 9 62 - - HYPH cord-261186-4p1cwb2e 9 63 8.51 8.51 CD cord-261186-4p1cwb2e 9 64 ) ) -RRB- cord-261186-4p1cwb2e 9 65 . . . cord-261186-4p1cwb2e 10 1 The the DT cord-261186-4p1cwb2e 10 2 analysis analysis NN cord-261186-4p1cwb2e 10 3 performed perform VBN cord-261186-4p1cwb2e 10 4 in in IN cord-261186-4p1cwb2e 10 5 this this DT cord-261186-4p1cwb2e 10 6 study study NN cord-261186-4p1cwb2e 10 7 was be VBD cord-261186-4p1cwb2e 10 8 adjusted adjust VBN cord-261186-4p1cwb2e 10 9 for for IN cord-261186-4p1cwb2e 10 10 likely likely JJ cord-261186-4p1cwb2e 10 11 confounders confounder NNS cord-261186-4p1cwb2e 10 12 , , , cord-261186-4p1cwb2e 10 13 including include VBG cord-261186-4p1cwb2e 10 14 comorbidities comorbiditie NNS cord-261186-4p1cwb2e 10 15 , , , cord-261186-4p1cwb2e 10 16 demographics demographic NNS cord-261186-4p1cwb2e 10 17 and and CC cord-261186-4p1cwb2e 10 18 disease disease NN cord-261186-4p1cwb2e 10 19 severity severity NN cord-261186-4p1cwb2e 10 20 . . . cord-261186-4p1cwb2e 11 1 However however RB cord-261186-4p1cwb2e 11 2 , , , cord-261186-4p1cwb2e 11 3 due due IN cord-261186-4p1cwb2e 11 4 to to IN cord-261186-4p1cwb2e 11 5 the the DT cord-261186-4p1cwb2e 11 6 observational observational JJ cord-261186-4p1cwb2e 11 7 study study NN cord-261186-4p1cwb2e 11 8 design design NN cord-261186-4p1cwb2e 11 9 it -PRON- PRP cord-261186-4p1cwb2e 11 10 is be VBZ cord-261186-4p1cwb2e 11 11 possible possible JJ cord-261186-4p1cwb2e 11 12 that that IN cord-261186-4p1cwb2e 11 13 some some DT cord-261186-4p1cwb2e 11 14 amount amount NN cord-261186-4p1cwb2e 11 15 of of IN cord-261186-4p1cwb2e 11 16 unmeasured unmeasured JJ cord-261186-4p1cwb2e 11 17 confounding confounding JJ cord-261186-4p1cwb2e 11 18 remains remain NNS cord-261186-4p1cwb2e 11 19 . . . cord-261186-4p1cwb2e 12 1 Later later RB cord-261186-4p1cwb2e 12 2 on on RB cord-261186-4p1cwb2e 12 3 , , , cord-261186-4p1cwb2e 12 4 Mehra Mehra NNP cord-261186-4p1cwb2e 12 5 et et NNP cord-261186-4p1cwb2e 12 6 al al NNP cord-261186-4p1cwb2e 12 7 ( ( -LRB- cord-261186-4p1cwb2e 12 8 9 9 CD cord-261186-4p1cwb2e 12 9 ) ) -RRB- cord-261186-4p1cwb2e 12 10 , , , cord-261186-4p1cwb2e 12 11 reported report VBD cord-261186-4p1cwb2e 12 12 a a DT cord-261186-4p1cwb2e 12 13 large large JJ cord-261186-4p1cwb2e 12 14 international international JJ cord-261186-4p1cwb2e 12 15 observational observational JJ cord-261186-4p1cwb2e 12 16 registry registry NN cord-261186-4p1cwb2e 12 17 including include VBG cord-261186-4p1cwb2e 12 18 data datum NNS cord-261186-4p1cwb2e 12 19 from from IN cord-261186-4p1cwb2e 12 20 96032 96032 CD cord-261186-4p1cwb2e 12 21 patients patient NNS cord-261186-4p1cwb2e 12 22 from from IN cord-261186-4p1cwb2e 12 23 671 671 CD cord-261186-4p1cwb2e 12 24 hospitals hospital NNS cord-261186-4p1cwb2e 12 25 in in IN cord-261186-4p1cwb2e 12 26 six six CD cord-261186-4p1cwb2e 12 27 continents continent NNS cord-261186-4p1cwb2e 12 28 ( ( -LRB- cord-261186-4p1cwb2e 12 29 mainly mainly RB cord-261186-4p1cwb2e 12 30 North North NNP cord-261186-4p1cwb2e 12 31 America America NNP cord-261186-4p1cwb2e 12 32 and and CC cord-261186-4p1cwb2e 12 33 Europe Europe NNP cord-261186-4p1cwb2e 12 34 ) ) -RRB- cord-261186-4p1cwb2e 12 35 who who WP cord-261186-4p1cwb2e 12 36 received receive VBD cord-261186-4p1cwb2e 12 37 CQ CQ NNP cord-261186-4p1cwb2e 12 38 ( ( -LRB- cord-261186-4p1cwb2e 12 39 n=1868 n=1868 NNP cord-261186-4p1cwb2e 12 40 ) ) -RRB- cord-261186-4p1cwb2e 12 41 ; ; : cord-261186-4p1cwb2e 12 42 CQ CQ NNP cord-261186-4p1cwb2e 12 43 plus plus CC cord-261186-4p1cwb2e 12 44 macrolide macrolide NN cord-261186-4p1cwb2e 12 45 ( ( -LRB- cord-261186-4p1cwb2e 12 46 n=3783 n=3783 CD cord-261186-4p1cwb2e 12 47 ) ) -RRB- cord-261186-4p1cwb2e 12 48 ; ; : cord-261186-4p1cwb2e 12 49 HCQ HCQ NNP cord-261186-4p1cwb2e 12 50 ( ( -LRB- cord-261186-4p1cwb2e 12 51 n=3016 n=3016 NN cord-261186-4p1cwb2e 12 52 ) ) -RRB- cord-261186-4p1cwb2e 12 53 ; ; : cord-261186-4p1cwb2e 12 54 HCQ hcq NN cord-261186-4p1cwb2e 12 55 plus plus CC cord-261186-4p1cwb2e 12 56 macrolide macrolide NN cord-261186-4p1cwb2e 12 57 ( ( -LRB- cord-261186-4p1cwb2e 12 58 n=6221 n=6221 NFP cord-261186-4p1cwb2e 12 59 ) ) -RRB- cord-261186-4p1cwb2e 12 60 versus versus IN cord-261186-4p1cwb2e 12 61 none none NN cord-261186-4p1cwb2e 12 62 of of IN cord-261186-4p1cwb2e 12 63 these these DT cord-261186-4p1cwb2e 12 64 drugs drug NNS cord-261186-4p1cwb2e 12 65 ( ( -LRB- cord-261186-4p1cwb2e 12 66 n=81144 n=81144 CD cord-261186-4p1cwb2e 12 67 ) ) -RRB- cord-261186-4p1cwb2e 12 68 and and CC cord-261186-4p1cwb2e 12 69 found find VBD cord-261186-4p1cwb2e 12 70 that that IN cord-261186-4p1cwb2e 12 71 the the DT cord-261186-4p1cwb2e 12 72 use use NN cord-261186-4p1cwb2e 12 73 of of IN cord-261186-4p1cwb2e 12 74 CQ CQ NNP cord-261186-4p1cwb2e 12 75 or or CC cord-261186-4p1cwb2e 12 76 HCQ HCQ NNP cord-261186-4p1cwb2e 12 77 with with IN cord-261186-4p1cwb2e 12 78 or or CC cord-261186-4p1cwb2e 12 79 without without IN cord-261186-4p1cwb2e 12 80 macrolides macrolide NNS cord-261186-4p1cwb2e 12 81 was be VBD cord-261186-4p1cwb2e 12 82 independently independently RB cord-261186-4p1cwb2e 12 83 associated associate VBN cord-261186-4p1cwb2e 12 84 with with IN cord-261186-4p1cwb2e 12 85 a a DT cord-261186-4p1cwb2e 12 86 higher high JJR cord-261186-4p1cwb2e 12 87 risk risk NN cord-261186-4p1cwb2e 12 88 of of IN cord-261186-4p1cwb2e 12 89 in in IN cord-261186-4p1cwb2e 12 90 - - HYPH cord-261186-4p1cwb2e 12 91 hospital hospital NN cord-261186-4p1cwb2e 12 92 mortality mortality NN cord-261186-4p1cwb2e 12 93 and and CC cord-261186-4p1cwb2e 12 94 an an DT cord-261186-4p1cwb2e 12 95 increased increase VBN cord-261186-4p1cwb2e 12 96 frequency frequency NN cord-261186-4p1cwb2e 12 97 of of IN cord-261186-4p1cwb2e 12 98 de de JJ cord-261186-4p1cwb2e 12 99 - - JJ cord-261186-4p1cwb2e 12 100 novo novo JJ cord-261186-4p1cwb2e 12 101 ventricular ventricular JJ cord-261186-4p1cwb2e 12 102 arrhythmia arrhythmia NN cord-261186-4p1cwb2e 12 103 ( ( -LRB- cord-261186-4p1cwb2e 12 104 non non JJ cord-261186-4p1cwb2e 12 105 - - JJ cord-261186-4p1cwb2e 12 106 sustained sustained JJ cord-261186-4p1cwb2e 12 107 or or CC cord-261186-4p1cwb2e 12 108 sustained sustain VBN cord-261186-4p1cwb2e 12 109 ventricular ventricular JJ cord-261186-4p1cwb2e 12 110 tachycardia tachycardia JJ cord-261186-4p1cwb2e 12 111 or or CC cord-261186-4p1cwb2e 12 112 ventricular ventricular JJ cord-261186-4p1cwb2e 12 113 fibrillation fibrillation NN cord-261186-4p1cwb2e 12 114 ) ) -RRB- cord-261186-4p1cwb2e 12 115 . . . cord-261186-4p1cwb2e 13 1 The the DT cord-261186-4p1cwb2e 13 2 authors author NNS cord-261186-4p1cwb2e 13 3 state state VBP cord-261186-4p1cwb2e 13 4 that that IN cord-261186-4p1cwb2e 13 5 the the DT cord-261186-4p1cwb2e 13 6 combination combination NN cord-261186-4p1cwb2e 13 7 of of IN cord-261186-4p1cwb2e 13 8 CQ CQ NNP cord-261186-4p1cwb2e 13 9 or or CC cord-261186-4p1cwb2e 13 10 HCQ HCQ NNP cord-261186-4p1cwb2e 13 11 with with IN cord-261186-4p1cwb2e 13 12 a a DT cord-261186-4p1cwb2e 13 13 macrolide macrolide NN cord-261186-4p1cwb2e 13 14 increased increase VBD cord-261186-4p1cwb2e 13 15 the the DT cord-261186-4p1cwb2e 13 16 hazard hazard NN cord-261186-4p1cwb2e 13 17 of of IN cord-261186-4p1cwb2e 13 18 de de NNP cord-261186-4p1cwb2e 13 19 - - JJ cord-261186-4p1cwb2e 13 20 novo novo JJ cord-261186-4p1cwb2e 13 21 ventricular ventricular JJ cord-261186-4p1cwb2e 13 22 arrhythmias arrhythmias RB cord-261186-4p1cwb2e 13 23 : : : cord-261186-4p1cwb2e 13 24 CQ CQ NNP cord-261186-4p1cwb2e 13 25 with with IN cord-261186-4p1cwb2e 13 26 a a DT cord-261186-4p1cwb2e 13 27 macrolide macrolide NN cord-261186-4p1cwb2e 13 28 ( ( -LRB- cord-261186-4p1cwb2e 13 29 HR HR NNP cord-261186-4p1cwb2e 13 30 4.01 4.01 CD cord-261186-4p1cwb2e 13 31 ; ; : cord-261186-4p1cwb2e 13 32 95 95 CD cord-261186-4p1cwb2e 13 33 % % NN cord-261186-4p1cwb2e 13 34 CI CI NNP cord-261186-4p1cwb2e 13 35 3.34 3.34 CD cord-261186-4p1cwb2e 13 36 -4.81 -4.81 CD cord-261186-4p1cwb2e 13 37 ) ) -RRB- cord-261186-4p1cwb2e 13 38 ; ; : cord-261186-4p1cwb2e 13 39 CQ CQ NNP cord-261186-4p1cwb2e 13 40 alone alone RB cord-261186-4p1cwb2e 13 41 ( ( -LRB- cord-261186-4p1cwb2e 13 42 HR HR NNP cord-261186-4p1cwb2e 13 43 3.56 3.56 CD cord-261186-4p1cwb2e 13 44 ; ; : cord-261186-4p1cwb2e 13 45 95 95 CD cord-261186-4p1cwb2e 13 46 % % NN cord-261186-4p1cwb2e 13 47 CI CI NNP cord-261186-4p1cwb2e 13 48 2.76 2.76 CD cord-261186-4p1cwb2e 13 49 -4.59 -4.59 CD cord-261186-4p1cwb2e 13 50 ) ) -RRB- cord-261186-4p1cwb2e 13 51 ; ; : cord-261186-4p1cwb2e 13 52 HCQ HCQ NNP cord-261186-4p1cwb2e 13 53 with with IN cord-261186-4p1cwb2e 13 54 a a DT cord-261186-4p1cwb2e 13 55 macrolide macrolide NN cord-261186-4p1cwb2e 13 56 ( ( -LRB- cord-261186-4p1cwb2e 13 57 HR HR NNP cord-261186-4p1cwb2e 13 58 5.10 5.10 CD cord-261186-4p1cwb2e 13 59 ; ; : cord-261186-4p1cwb2e 13 60 95 95 CD cord-261186-4p1cwb2e 13 61 % % NN cord-261186-4p1cwb2e 13 62 CI ci NN cord-261186-4p1cwb2e 14 1 4.10 4.10 CD cord-261186-4p1cwb2e 14 2 -5.98 -5.98 CD cord-261186-4p1cwb2e 14 3 ) ) -RRB- cord-261186-4p1cwb2e 15 1 and and CC cord-261186-4p1cwb2e 15 2 HCQ HCQ NNP cord-261186-4p1cwb2e 15 3 alone alone JJ cord-261186-4p1cwb2e 15 4 ( ( -LRB- cord-261186-4p1cwb2e 15 5 HR HR NNP cord-261186-4p1cwb2e 15 6 2.36 2.36 CD cord-261186-4p1cwb2e 15 7 ; ; : cord-261186-4p1cwb2e 15 8 95 95 CD cord-261186-4p1cwb2e 15 9 % % NN cord-261186-4p1cwb2e 15 10 CI CI NNP cord-261186-4p1cwb2e 15 11 1.93 1.93 CD cord-261186-4p1cwb2e 15 12 -2.90 -2.90 CD cord-261186-4p1cwb2e 15 13 ) ) -RRB- cord-261186-4p1cwb2e 15 14 . . . cord-261186-4p1cwb2e 16 1 Predictors predictor NNS cord-261186-4p1cwb2e 16 2 of of IN cord-261186-4p1cwb2e 16 3 ventricular ventricular JJ cord-261186-4p1cwb2e 16 4 arrhythmia arrhythmia NN cord-261186-4p1cwb2e 16 5 were be VBD cord-261186-4p1cwb2e 16 6 also also RB cord-261186-4p1cwb2e 16 7 investigated investigate VBN cord-261186-4p1cwb2e 16 8 and and CC cord-261186-4p1cwb2e 16 9 the the DT cord-261186-4p1cwb2e 16 10 variables variable NNS cord-261186-4p1cwb2e 16 11 found find VBN cord-261186-4p1cwb2e 16 12 to to TO cord-261186-4p1cwb2e 16 13 be be VB cord-261186-4p1cwb2e 16 14 independently independently RB cord-261186-4p1cwb2e 16 15 associated associate VBN cord-261186-4p1cwb2e 16 16 with with IN cord-261186-4p1cwb2e 16 17 higher high JJR cord-261186-4p1cwb2e 16 18 risk risk NN cord-261186-4p1cwb2e 16 19 of of IN cord-261186-4p1cwb2e 16 20 de de NNP cord-261186-4p1cwb2e 16 21 - - JJ cord-261186-4p1cwb2e 16 22 novo novo JJ cord-261186-4p1cwb2e 16 23 ventricular ventricular JJ cord-261186-4p1cwb2e 16 24 arrhythmias arrhythmia NNS cord-261186-4p1cwb2e 16 25 were be VBD cord-261186-4p1cwb2e 16 26 CQ CQ NNP cord-261186-4p1cwb2e 16 27 or or CC cord-261186-4p1cwb2e 16 28 HCQ HCQ NNP cord-261186-4p1cwb2e 16 29 with with IN cord-261186-4p1cwb2e 16 30 or or CC cord-261186-4p1cwb2e 16 31 without without IN cord-261186-4p1cwb2e 16 32 macrolides macrolide NNS cord-261186-4p1cwb2e 16 33 and and CC cord-261186-4p1cwb2e 16 34 baseline baseline JJ cord-261186-4p1cwb2e 16 35 comorbidities comorbiditie NNS cord-261186-4p1cwb2e 16 36 such such JJ cord-261186-4p1cwb2e 16 37 as as IN cord-261186-4p1cwb2e 16 38 coronary coronary JJ cord-261186-4p1cwb2e 16 39 artery artery NN cord-261186-4p1cwb2e 16 40 disease disease NN cord-261186-4p1cwb2e 16 41 , , , cord-261186-4p1cwb2e 16 42 congestive congestive JJ cord-261186-4p1cwb2e 16 43 heart heart NN cord-261186-4p1cwb2e 16 44 failure failure NN cord-261186-4p1cwb2e 16 45 , , , cord-261186-4p1cwb2e 16 46 history history NN cord-261186-4p1cwb2e 16 47 of of IN cord-261186-4p1cwb2e 16 48 cardiac cardiac JJ cord-261186-4p1cwb2e 16 49 arrhythmia arrhythmia NN cord-261186-4p1cwb2e 16 50 , , , cord-261186-4p1cwb2e 16 51 and and CC cord-261186-4p1cwb2e 16 52 chronic chronic JJ cord-261186-4p1cwb2e 16 53 obstructive obstructive JJ cord-261186-4p1cwb2e 16 54 pulmonary pulmonary JJ cord-261186-4p1cwb2e 16 55 disease disease NN cord-261186-4p1cwb2e 16 56 . . . cord-261186-4p1cwb2e 17 1 The the DT cord-261186-4p1cwb2e 17 2 researchers researcher NNS cord-261186-4p1cwb2e 17 3 argue argue VBP cord-261186-4p1cwb2e 17 4 that that IN cord-261186-4p1cwb2e 17 5 the the DT cord-261186-4p1cwb2e 17 6 presence presence NN cord-261186-4p1cwb2e 17 7 of of IN cord-261186-4p1cwb2e 17 8 underlying underlie VBG cord-261186-4p1cwb2e 17 9 cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 17 10 disease disease NN cord-261186-4p1cwb2e 17 11 could could MD cord-261186-4p1cwb2e 17 12 represent represent VB cord-261186-4p1cwb2e 17 13 a a DT cord-261186-4p1cwb2e 17 14 partial partial JJ cord-261186-4p1cwb2e 17 15 explanation explanation NN cord-261186-4p1cwb2e 17 16 of of IN cord-261186-4p1cwb2e 17 17 the the DT cord-261186-4p1cwb2e 17 18 cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 17 19 toxicity toxicity NN cord-261186-4p1cwb2e 17 20 associated associate VBN cord-261186-4p1cwb2e 17 21 with with IN cord-261186-4p1cwb2e 17 22 the the DT cord-261186-4p1cwb2e 17 23 use use NN cord-261186-4p1cwb2e 17 24 of of IN cord-261186-4p1cwb2e 17 25 CQ CQ NNP cord-261186-4p1cwb2e 17 26 or or CC cord-261186-4p1cwb2e 17 27 HCQ HCQ NNP cord-261186-4p1cwb2e 17 28 particularly particularly RB cord-261186-4p1cwb2e 17 29 with with IN cord-261186-4p1cwb2e 17 30 the the DT cord-261186-4p1cwb2e 17 31 combination combination NN cord-261186-4p1cwb2e 17 32 of of IN cord-261186-4p1cwb2e 17 33 macrolides macrolide NNS cord-261186-4p1cwb2e 17 34 . . . cord-261186-4p1cwb2e 18 1 Notably notably RB cord-261186-4p1cwb2e 18 2 , , , cord-261186-4p1cwb2e 18 3 a a DT cord-261186-4p1cwb2e 18 4 propensity propensity NN cord-261186-4p1cwb2e 18 5 score score NN cord-261186-4p1cwb2e 18 6 matching matching NN cord-261186-4p1cwb2e 18 7 analysis analysis NN cord-261186-4p1cwb2e 18 8 was be VBD cord-261186-4p1cwb2e 18 9 conducted conduct VBN cord-261186-4p1cwb2e 18 10 to to TO cord-261186-4p1cwb2e 18 11 mitigate mitigate VB cord-261186-4p1cwb2e 18 12 potential potential JJ cord-261186-4p1cwb2e 18 13 confounders confounder NNS cord-261186-4p1cwb2e 18 14 . . . cord-261186-4p1cwb2e 19 1 Moreover moreover RB cord-261186-4p1cwb2e 19 2 , , , cord-261186-4p1cwb2e 19 3 Cox Cox NNP cord-261186-4p1cwb2e 19 4 proportional proportional JJ cord-261186-4p1cwb2e 19 5 hazards hazard NNS cord-261186-4p1cwb2e 19 6 models model NNS cord-261186-4p1cwb2e 19 7 and and CC cord-261186-4p1cwb2e 19 8 a a DT cord-261186-4p1cwb2e 19 9 tipping tipping NN cord-261186-4p1cwb2e 19 10 - - HYPH cord-261186-4p1cwb2e 19 11 point point NN cord-261186-4p1cwb2e 19 12 analysis analysis NN cord-261186-4p1cwb2e 19 13 were be VBD cord-261186-4p1cwb2e 19 14 performed perform VBN cord-261186-4p1cwb2e 19 15 to to TO cord-261186-4p1cwb2e 19 16 assess assess VB cord-261186-4p1cwb2e 19 17 the the DT cord-261186-4p1cwb2e 19 18 robustness robustness NN cord-261186-4p1cwb2e 19 19 of of IN cord-261186-4p1cwb2e 19 20 the the DT cord-261186-4p1cwb2e 19 21 estimates estimate NNS cord-261186-4p1cwb2e 19 22 . . . cord-261186-4p1cwb2e 20 1 Clearly clearly RB cord-261186-4p1cwb2e 20 2 , , , cord-261186-4p1cwb2e 20 3 this this DT cord-261186-4p1cwb2e 20 4 study study NN cord-261186-4p1cwb2e 20 5 represents represent VBZ cord-261186-4p1cwb2e 20 6 a a DT cord-261186-4p1cwb2e 20 7 potential potential JJ cord-261186-4p1cwb2e 20 8 landmark landmark NN cord-261186-4p1cwb2e 20 9 regarding regard VBG cord-261186-4p1cwb2e 20 10 safety safety NN cord-261186-4p1cwb2e 20 11 and and CC cord-261186-4p1cwb2e 20 12 efficacy efficacy NN cord-261186-4p1cwb2e 20 13 of of IN cord-261186-4p1cwb2e 20 14 CQ CQ NNP cord-261186-4p1cwb2e 20 15 and and CC cord-261186-4p1cwb2e 20 16 HCQ HCQ NNP cord-261186-4p1cwb2e 20 17 , , , cord-261186-4p1cwb2e 20 18 either either CC cord-261186-4p1cwb2e 20 19 alone alone RB cord-261186-4p1cwb2e 20 20 or or CC cord-261186-4p1cwb2e 20 21 in in IN cord-261186-4p1cwb2e 20 22 combination combination NN cord-261186-4p1cwb2e 20 23 with with IN cord-261186-4p1cwb2e 20 24 macrolides macrolide NNS cord-261186-4p1cwb2e 20 25 , , , cord-261186-4p1cwb2e 20 26 for for IN cord-261186-4p1cwb2e 20 27 the the DT cord-261186-4p1cwb2e 20 28 treatment treatment NN cord-261186-4p1cwb2e 20 29 of of IN cord-261186-4p1cwb2e 20 30 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 20 31 . . . cord-261186-4p1cwb2e 21 1 However however RB cord-261186-4p1cwb2e 21 2 , , , cord-261186-4p1cwb2e 21 3 the the DT cord-261186-4p1cwb2e 21 4 observational observational JJ cord-261186-4p1cwb2e 21 5 retrospective retrospective JJ cord-261186-4p1cwb2e 21 6 design design NN cord-261186-4p1cwb2e 21 7 limits limit VBZ cord-261186-4p1cwb2e 21 8 the the DT cord-261186-4p1cwb2e 21 9 study study NN cord-261186-4p1cwb2e 21 10 's 's POS cord-261186-4p1cwb2e 21 11 implications implication NNS cord-261186-4p1cwb2e 21 12 . . . cord-261186-4p1cwb2e 22 1 In in IN cord-261186-4p1cwb2e 22 2 addition addition NN cord-261186-4p1cwb2e 22 3 to to IN cord-261186-4p1cwb2e 22 4 the the DT cord-261186-4p1cwb2e 22 5 cardiotoxic cardiotoxic JJ cord-261186-4p1cwb2e 22 6 considerations consideration NNS cord-261186-4p1cwb2e 22 7 mentioned mention VBN cord-261186-4p1cwb2e 22 8 by by IN cord-261186-4p1cwb2e 22 9 Aggarwal Aggarwal NNP cord-261186-4p1cwb2e 22 10 , , , cord-261186-4p1cwb2e 22 11 et et NNP cord-261186-4p1cwb2e 22 12 al al NNP cord-261186-4p1cwb2e 22 13 ( ( -LRB- cord-261186-4p1cwb2e 22 14 1 1 CD cord-261186-4p1cwb2e 22 15 ) ) -RRB- cord-261186-4p1cwb2e 22 16 , , , cord-261186-4p1cwb2e 22 17 relevant relevant JJ cord-261186-4p1cwb2e 22 18 cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 22 19 side side NN cord-261186-4p1cwb2e 22 20 effects effect NNS cord-261186-4p1cwb2e 22 21 and and CC cord-261186-4p1cwb2e 22 22 toxicities toxicity NNS cord-261186-4p1cwb2e 22 23 associated associate VBN cord-261186-4p1cwb2e 22 24 with with IN cord-261186-4p1cwb2e 22 25 the the DT cord-261186-4p1cwb2e 22 26 use use NN cord-261186-4p1cwb2e 22 27 of of IN cord-261186-4p1cwb2e 22 28 repurposing repurpose VBG cord-261186-4p1cwb2e 22 29 drugs drug NNS cord-261186-4p1cwb2e 22 30 for for IN cord-261186-4p1cwb2e 22 31 the the DT cord-261186-4p1cwb2e 22 32 treatment treatment NN cord-261186-4p1cwb2e 22 33 of of IN cord-261186-4p1cwb2e 22 34 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 22 35 have have VBP cord-261186-4p1cwb2e 22 36 been be VBN cord-261186-4p1cwb2e 22 37 stated state VBN cord-261186-4p1cwb2e 22 38 by by IN cord-261186-4p1cwb2e 22 39 researchers researcher NNS cord-261186-4p1cwb2e 22 40 of of IN cord-261186-4p1cwb2e 22 41 cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 22 42 disease disease NN cord-261186-4p1cwb2e 22 43 who who WP cord-261186-4p1cwb2e 22 44 stress stress VBP cord-261186-4p1cwb2e 22 45 the the DT cord-261186-4p1cwb2e 22 46 risk risk NN cord-261186-4p1cwb2e 22 47 of of IN cord-261186-4p1cwb2e 22 48 QT qt NN cord-261186-4p1cwb2e 22 49 interval interval NN cord-261186-4p1cwb2e 22 50 prolongation prolongation NN cord-261186-4p1cwb2e 22 51 , , , cord-261186-4p1cwb2e 22 52 thrombocytopenia thrombocytopenia NN cord-261186-4p1cwb2e 22 53 and and CC cord-261186-4p1cwb2e 22 54 anaemia anaemia NN cord-261186-4p1cwb2e 22 55 specifically specifically RB cord-261186-4p1cwb2e 22 56 with with IN cord-261186-4p1cwb2e 22 57 the the DT cord-261186-4p1cwb2e 22 58 use use NN cord-261186-4p1cwb2e 22 59 of of IN cord-261186-4p1cwb2e 22 60 CQ CQ NNP cord-261186-4p1cwb2e 22 61 and and CC cord-261186-4p1cwb2e 22 62 HCQ HCQ NNP cord-261186-4p1cwb2e 22 63 ( ( -LRB- cord-261186-4p1cwb2e 22 64 10 10 CD cord-261186-4p1cwb2e 22 65 ) ) -RRB- cord-261186-4p1cwb2e 22 66 . . . cord-261186-4p1cwb2e 23 1 In in IN cord-261186-4p1cwb2e 23 2 conclusion conclusion NN cord-261186-4p1cwb2e 23 3 , , , cord-261186-4p1cwb2e 23 4 it -PRON- PRP cord-261186-4p1cwb2e 23 5 is be VBZ cord-261186-4p1cwb2e 23 6 not not RB cord-261186-4p1cwb2e 23 7 clear clear JJ cord-261186-4p1cwb2e 23 8 whether whether IN cord-261186-4p1cwb2e 23 9 the the DT cord-261186-4p1cwb2e 23 10 risk risk NN cord-261186-4p1cwb2e 23 11 of of IN cord-261186-4p1cwb2e 23 12 toxic toxic JJ cord-261186-4p1cwb2e 23 13 effects effect NNS cord-261186-4p1cwb2e 23 14 may may MD cord-261186-4p1cwb2e 23 15 outweigh outweigh VB cord-261186-4p1cwb2e 23 16 the the DT cord-261186-4p1cwb2e 23 17 benefits benefit NNS cord-261186-4p1cwb2e 23 18 of of IN cord-261186-4p1cwb2e 23 19 potential potential JJ cord-261186-4p1cwb2e 23 20 COVID-19 covid-19 CD cord-261186-4p1cwb2e 23 21 treatments treatment NNS cord-261186-4p1cwb2e 23 22 . . . cord-261186-4p1cwb2e 24 1 A a DT cord-261186-4p1cwb2e 24 2 decisive decisive JJ cord-261186-4p1cwb2e 24 3 answer answer NN cord-261186-4p1cwb2e 24 4 still still RB cord-261186-4p1cwb2e 24 5 awaits await VBZ cord-261186-4p1cwb2e 24 6 the the DT cord-261186-4p1cwb2e 24 7 results result NNS cord-261186-4p1cwb2e 24 8 of of IN cord-261186-4p1cwb2e 24 9 high high JJ cord-261186-4p1cwb2e 24 10 quality quality NN cord-261186-4p1cwb2e 24 11 large large JJ cord-261186-4p1cwb2e 24 12 randomized randomize VBN cord-261186-4p1cwb2e 24 13 controlled control VBN cord-261186-4p1cwb2e 24 14 trials trial NNS cord-261186-4p1cwb2e 24 15 . . . cord-261186-4p1cwb2e 25 1 Cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 25 2 Safety Safety NNP cord-261186-4p1cwb2e 25 3 of of IN cord-261186-4p1cwb2e 25 4 Potential potential JJ cord-261186-4p1cwb2e 25 5 Drugs drug NNS cord-261186-4p1cwb2e 25 6 for for IN cord-261186-4p1cwb2e 25 7 the the DT cord-261186-4p1cwb2e 25 8 Treatment Treatment NNP cord-261186-4p1cwb2e 25 9 of of IN cord-261186-4p1cwb2e 25 10 Coronavirus Coronavirus NNP cord-261186-4p1cwb2e 25 11 Disease Disease NNP cord-261186-4p1cwb2e 25 12 Effect Effect NNP cord-261186-4p1cwb2e 25 13 of of IN cord-261186-4p1cwb2e 25 14 High High NNP cord-261186-4p1cwb2e 25 15 vs vs IN cord-261186-4p1cwb2e 25 16 Low Low NNP cord-261186-4p1cwb2e 25 17 Doses Doses NNPS cord-261186-4p1cwb2e 25 18 of of IN cord-261186-4p1cwb2e 25 19 Chloroquine Chloroquine NNP cord-261186-4p1cwb2e 25 20 Diphosphate Diphosphate NNP cord-261186-4p1cwb2e 25 21 as as IN cord-261186-4p1cwb2e 25 22 Adjunctive Adjunctive NNP cord-261186-4p1cwb2e 25 23 Therapy Therapy NNP cord-261186-4p1cwb2e 25 24 for for IN cord-261186-4p1cwb2e 25 25 Patients patient NNS cord-261186-4p1cwb2e 25 26 Hospitalized hospitalize VBN cord-261186-4p1cwb2e 25 27 With with IN cord-261186-4p1cwb2e 25 28 Severe severe JJ cord-261186-4p1cwb2e 25 29 Acute acute JJ cord-261186-4p1cwb2e 25 30 Respiratory Respiratory NNP cord-261186-4p1cwb2e 25 31 Syndrome Syndrome NNP cord-261186-4p1cwb2e 25 32 Coronavirus Coronavirus NNP cord-261186-4p1cwb2e 25 33 2 2 CD cord-261186-4p1cwb2e 26 1 ( ( -LRB- cord-261186-4p1cwb2e 26 2 SARS SARS NNP cord-261186-4p1cwb2e 26 3 - - HYPH cord-261186-4p1cwb2e 26 4 CoV-2 CoV-2 NNP cord-261186-4p1cwb2e 26 5 ) ) -RRB- cord-261186-4p1cwb2e 26 6 Infection infection NN cord-261186-4p1cwb2e 26 7 : : : cord-261186-4p1cwb2e 26 8 A a DT cord-261186-4p1cwb2e 26 9 Randomized Randomized NNP cord-261186-4p1cwb2e 26 10 Clinical Clinical NNP cord-261186-4p1cwb2e 26 11 Trial Trial NNP cord-261186-4p1cwb2e 26 12 Clinical clinical JJ cord-261186-4p1cwb2e 26 13 and and CC cord-261186-4p1cwb2e 26 14 microbiological microbiological JJ cord-261186-4p1cwb2e 26 15 effect effect NN cord-261186-4p1cwb2e 26 16 of of IN cord-261186-4p1cwb2e 26 17 a a DT cord-261186-4p1cwb2e 26 18 combination combination NN cord-261186-4p1cwb2e 26 19 of of IN cord-261186-4p1cwb2e 26 20 hydroxychloroquine hydroxychloroquine NN cord-261186-4p1cwb2e 26 21 and and CC cord-261186-4p1cwb2e 26 22 azithromycin azithromycin NNP cord-261186-4p1cwb2e 26 23 in in IN cord-261186-4p1cwb2e 26 24 80 80 CD cord-261186-4p1cwb2e 26 25 COVID-19 covid-19 JJ cord-261186-4p1cwb2e 26 26 patients patient NNS cord-261186-4p1cwb2e 26 27 with with IN cord-261186-4p1cwb2e 26 28 at at RB cord-261186-4p1cwb2e 26 29 least least JJS cord-261186-4p1cwb2e 26 30 a a DT cord-261186-4p1cwb2e 26 31 six six CD cord-261186-4p1cwb2e 26 32 - - HYPH cord-261186-4p1cwb2e 26 33 day day NN cord-261186-4p1cwb2e 26 34 follow follow VB cord-261186-4p1cwb2e 26 35 up up RP cord-261186-4p1cwb2e 26 36 : : : cord-261186-4p1cwb2e 26 37 A a DT cord-261186-4p1cwb2e 26 38 pilot pilot NN cord-261186-4p1cwb2e 26 39 observational observational JJ cord-261186-4p1cwb2e 26 40 study study NN cord-261186-4p1cwb2e 27 1 The the DT cord-261186-4p1cwb2e 27 2 QT QT NNP cord-261186-4p1cwb2e 27 3 interval interval NN cord-261186-4p1cwb2e 27 4 in in IN cord-261186-4p1cwb2e 27 5 patients patient NNS cord-261186-4p1cwb2e 27 6 with with IN cord-261186-4p1cwb2e 27 7 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 27 8 treated treat VBN cord-261186-4p1cwb2e 27 9 with with IN cord-261186-4p1cwb2e 27 10 hydroxychloroquine hydroxychloroquine NN cord-261186-4p1cwb2e 27 11 and and CC cord-261186-4p1cwb2e 27 12 azithromycin azithromycin NNP cord-261186-4p1cwb2e 27 13 Assessment Assessment NNP cord-261186-4p1cwb2e 27 14 of of IN cord-261186-4p1cwb2e 27 15 QT QT NNP cord-261186-4p1cwb2e 27 16 Intervals Intervals NNPS cord-261186-4p1cwb2e 27 17 in in IN cord-261186-4p1cwb2e 27 18 a a DT cord-261186-4p1cwb2e 27 19 case case NN cord-261186-4p1cwb2e 27 20 series series NN cord-261186-4p1cwb2e 27 21 of of IN cord-261186-4p1cwb2e 27 22 patients patient NNS cord-261186-4p1cwb2e 27 23 with with IN cord-261186-4p1cwb2e 27 24 coronavirus coronavirus NN cord-261186-4p1cwb2e 27 25 disease disease NN cord-261186-4p1cwb2e 27 26 2019 2019 CD cord-261186-4p1cwb2e 27 27 ( ( -LRB- cord-261186-4p1cwb2e 27 28 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 27 29 ) ) -RRB- cord-261186-4p1cwb2e 27 30 infection infection NN cord-261186-4p1cwb2e 27 31 treated treat VBN cord-261186-4p1cwb2e 27 32 with with IN cord-261186-4p1cwb2e 27 33 hydroxychloroquine hydroxychloroquine NN cord-261186-4p1cwb2e 27 34 alone alone JJ cord-261186-4p1cwb2e 27 35 or or CC cord-261186-4p1cwb2e 27 36 in in IN cord-261186-4p1cwb2e 27 37 combination combination NN cord-261186-4p1cwb2e 27 38 with with IN cord-261186-4p1cwb2e 27 39 azithromycin azithromycin NNP cord-261186-4p1cwb2e 27 40 in in IN cord-261186-4p1cwb2e 27 41 an an DT cord-261186-4p1cwb2e 27 42 intensive intensive JJ cord-261186-4p1cwb2e 27 43 care care NN cord-261186-4p1cwb2e 27 44 unit unit NN cord-261186-4p1cwb2e 27 45 Risk Risk NNP cord-261186-4p1cwb2e 27 46 of of IN cord-261186-4p1cwb2e 27 47 QT QT NNP cord-261186-4p1cwb2e 27 48 interval interval NN cord-261186-4p1cwb2e 27 49 prolongation prolongation NN cord-261186-4p1cwb2e 27 50 associated associate VBN cord-261186-4p1cwb2e 27 51 with with IN cord-261186-4p1cwb2e 27 52 use use NN cord-261186-4p1cwb2e 27 53 of of IN cord-261186-4p1cwb2e 27 54 hydroxychloroquine hydroxychloroquine NN cord-261186-4p1cwb2e 27 55 with with IN cord-261186-4p1cwb2e 27 56 or or CC cord-261186-4p1cwb2e 27 57 without without IN cord-261186-4p1cwb2e 27 58 concomitant concomitant JJ cord-261186-4p1cwb2e 27 59 azithromycin azithromycin NNS cord-261186-4p1cwb2e 27 60 among among IN cord-261186-4p1cwb2e 27 61 hospitalized hospitalize VBN cord-261186-4p1cwb2e 27 62 patients patient NNS cord-261186-4p1cwb2e 27 63 testing test VBG cord-261186-4p1cwb2e 27 64 positive positive JJ cord-261186-4p1cwb2e 27 65 for for IN cord-261186-4p1cwb2e 27 66 coronavirus coronavirus NN cord-261186-4p1cwb2e 27 67 2019 2019 CD cord-261186-4p1cwb2e 27 68 ( ( -LRB- cord-261186-4p1cwb2e 27 69 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 27 70 ) ) -RRB- cord-261186-4p1cwb2e 27 71 infection infection NN cord-261186-4p1cwb2e 27 72 . . . cord-261186-4p1cwb2e 28 1 JAMA JAMA NNP cord-261186-4p1cwb2e 29 1 Cardiol Cardiol NNP cord-261186-4p1cwb2e 29 2 Clinical clinical JJ cord-261186-4p1cwb2e 29 3 efficacy efficacy NN cord-261186-4p1cwb2e 29 4 of of IN cord-261186-4p1cwb2e 29 5 hydroxychloroquine hydroxychloroquine NN cord-261186-4p1cwb2e 29 6 in in IN cord-261186-4p1cwb2e 29 7 patients patient NNS cord-261186-4p1cwb2e 29 8 with with IN cord-261186-4p1cwb2e 29 9 covid-19 covid-19 NNP cord-261186-4p1cwb2e 29 10 pneumonia pneumonia NN cord-261186-4p1cwb2e 29 11 who who WP cord-261186-4p1cwb2e 29 12 require require VBP cord-261186-4p1cwb2e 29 13 oxygen oxygen NN cord-261186-4p1cwb2e 29 14 : : : cord-261186-4p1cwb2e 29 15 observational observational JJ cord-261186-4p1cwb2e 29 16 comparative comparative JJ cord-261186-4p1cwb2e 29 17 study study NN cord-261186-4p1cwb2e 29 18 using use VBG cord-261186-4p1cwb2e 29 19 routine routine JJ cord-261186-4p1cwb2e 29 20 care care NN cord-261186-4p1cwb2e 29 21 data data NNPS cord-261186-4p1cwb2e 29 22 Association Association NNP cord-261186-4p1cwb2e 29 23 of of IN cord-261186-4p1cwb2e 29 24 Treatment Treatment NNP cord-261186-4p1cwb2e 29 25 With with IN cord-261186-4p1cwb2e 29 26 Hydroxychloroquine Hydroxychloroquine NNP cord-261186-4p1cwb2e 29 27 or or CC cord-261186-4p1cwb2e 29 28 Azithromycin Azithromycin NNP cord-261186-4p1cwb2e 29 29 With with IN cord-261186-4p1cwb2e 29 30 In in IN cord-261186-4p1cwb2e 29 31 - - HYPH cord-261186-4p1cwb2e 29 32 Hospital hospital NN cord-261186-4p1cwb2e 29 33 Mortality mortality NN cord-261186-4p1cwb2e 29 34 in in IN cord-261186-4p1cwb2e 29 35 Patients patient NNS cord-261186-4p1cwb2e 29 36 With with IN cord-261186-4p1cwb2e 29 37 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 29 38 in in IN cord-261186-4p1cwb2e 29 39 New New NNP cord-261186-4p1cwb2e 29 40 York York NNP cord-261186-4p1cwb2e 29 41 State State NNP cord-261186-4p1cwb2e 29 42 Hydroxychloroquine Hydroxychloroquine NNP cord-261186-4p1cwb2e 29 43 or or CC cord-261186-4p1cwb2e 29 44 chloroquine chloroquine NN cord-261186-4p1cwb2e 29 45 with with IN cord-261186-4p1cwb2e 29 46 or or CC cord-261186-4p1cwb2e 29 47 without without IN cord-261186-4p1cwb2e 29 48 a a DT cord-261186-4p1cwb2e 29 49 macrolide macrolide NN cord-261186-4p1cwb2e 29 50 for for IN cord-261186-4p1cwb2e 29 51 treatment treatment NN cord-261186-4p1cwb2e 29 52 of of IN cord-261186-4p1cwb2e 29 53 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 29 54 : : : cord-261186-4p1cwb2e 29 55 a a DT cord-261186-4p1cwb2e 29 56 multinational multinational JJ cord-261186-4p1cwb2e 29 57 registry registry NN cord-261186-4p1cwb2e 29 58 analysis analysis NN cord-261186-4p1cwb2e 29 59 . . . cord-261186-4p1cwb2e 30 1 The the DT cord-261186-4p1cwb2e 30 2 Lancet Lancet NNP cord-261186-4p1cwb2e 30 3 COVID-19 COVID-19 NNP cord-261186-4p1cwb2e 30 4 and and CC cord-261186-4p1cwb2e 30 5 the the DT cord-261186-4p1cwb2e 30 6 cardiovascular cardiovascular JJ cord-261186-4p1cwb2e 30 7 system system NN cord-261186-4p1cwb2e 30 8 : : : cord-261186-4p1cwb2e 30 9 implications implication NNS cord-261186-4p1cwb2e 30 10 for for IN cord-261186-4p1cwb2e 30 11 risk risk NN cord-261186-4p1cwb2e 30 12 assessment assessment NN cord-261186-4p1cwb2e 30 13 , , , cord-261186-4p1cwb2e 30 14 diagnosis diagnosis NN cord-261186-4p1cwb2e 30 15 , , , cord-261186-4p1cwb2e 30 16 and and CC cord-261186-4p1cwb2e 30 17 treatment treatment NN cord-261186-4p1cwb2e 30 18 options option NNS