id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-327609-no58ucyq	Murkey, Jamie A.	Hepatitis E Virus–Associated Meningoencephalitis in a Lung Transplant Recipient Diagnosed by Clinical Metagenomic Sequencing	2017-06-13		.txt	text/plain	1951	101	35	We describe a case of genotype 3a HEV meningoencephalitis diagnosed by metagenomic next-generation sequencing, illustrating the power of an unbiased molecular approach to microbial testing and the first reported case of HEV infection presumably acquired through lung transplantation. We demonstrate the power of clinical mNGS in elucidating the cause of uncommon and unexpected infections and identify a case of chronic HEV infection most likely transmitted through the transplanted lungs the patient had received 6 years prior. The case patient is a 58-year-old woman with a history of idiopathic pulmonary fibrosis status post bilateral lung transplant in 2011, migraines, hypercoagulability, and multiple sclerosis (MS) on chronic immunosuppression who was admitted to University of California, Los Angeles Medical Center in October 2016 with 8 days of fever, headache, nausea, vomiting, neck stiffness, and photophobia. Treatment of HEV infection in patients with a solid-organ transplant and chronic hepatitis	./cache/cord-327609-no58ucyq.txt	./txt/cord-327609-no58ucyq.txt