id	sid	tid	token	lemma	pos
cord-010027-r0tl01kq	1	1	key	key	NNP
cord-010027-r0tl01kq	1	2	:	:	:
cord-010027-r0tl01kq	1	3	cord-010027-r0tl01kq	cord-010027-r0tl01kq	JJ
cord-010027-r0tl01kq	1	4	authors	author	NNS
cord-010027-r0tl01kq	1	5	:	:	:
cord-010027-r0tl01kq	2	1	nan	nan	NNP
cord-010027-r0tl01kq	2	2	title	title	NN
cord-010027-r0tl01kq	2	3	:	:	:
cord-010027-r0tl01kq	2	4	Dublin	Dublin	NNP
cord-010027-r0tl01kq	2	5	Pathology	Pathology	NNP
cord-010027-r0tl01kq	2	6	2015	2015	CD
cord-010027-r0tl01kq	2	7	.	.	.
cord-010027-r0tl01kq	3	1	8th	8th	NNP
cord-010027-r0tl01kq	3	2	Joint	Joint	NNP
cord-010027-r0tl01kq	3	3	Meeting	Meeting	NNP
cord-010027-r0tl01kq	3	4	of	of	IN
cord-010027-r0tl01kq	3	5	the	the	DT
cord-010027-r0tl01kq	3	6	British	British	NNP
cord-010027-r0tl01kq	3	7	Division	Division	NNP
cord-010027-r0tl01kq	3	8	of	of	IN
cord-010027-r0tl01kq	3	9	the	the	DT
cord-010027-r0tl01kq	3	10	International	International	NNP
cord-010027-r0tl01kq	3	11	Academy	Academy	NNP
cord-010027-r0tl01kq	3	12	of	of	IN
cord-010027-r0tl01kq	3	13	Pathology	Pathology	NNP
cord-010027-r0tl01kq	3	14	and	and	CC
cord-010027-r0tl01kq	3	15	the	the	DT
cord-010027-r0tl01kq	3	16	Pathological	Pathological	NNP
cord-010027-r0tl01kq	3	17	Society	Society	NNP
cord-010027-r0tl01kq	3	18	of	of	IN
cord-010027-r0tl01kq	3	19	Great	Great	NNP
cord-010027-r0tl01kq	3	20	Britain	Britain	NNP
cord-010027-r0tl01kq	3	21	&	&	CC
cord-010027-r0tl01kq	3	22	Ireland	Ireland	NNP
cord-010027-r0tl01kq	3	23	date	date	NN
cord-010027-r0tl01kq	3	24	:	:	:
cord-010027-r0tl01kq	3	25	2015	2015	CD
cord-010027-r0tl01kq	3	26	-	-	HYPH
cord-010027-r0tl01kq	3	27	09	09	CD
cord-010027-r0tl01kq	3	28	-	-	SYM
cord-010027-r0tl01kq	3	29	15	15	CD
cord-010027-r0tl01kq	3	30	journal	journal	NN
cord-010027-r0tl01kq	3	31	:	:	:
cord-010027-r0tl01kq	4	1	J	J	NNP
cord-010027-r0tl01kq	4	2	Pathol	Pathol	NNP
cord-010027-r0tl01kq	4	3	DOI	DOI	NNP
cord-010027-r0tl01kq	4	4	:	:	:
cord-010027-r0tl01kq	5	1	10.1002	10.1002	CD
cord-010027-r0tl01kq	5	2	/	/	SYM
cord-010027-r0tl01kq	5	3	path.4631	path.4631	NNP
cord-010027-r0tl01kq	5	4	sha	sha	NNP
cord-010027-r0tl01kq	5	5	:	:	:
cord-010027-r0tl01kq	5	6	f8fee87468d60e19bc12d9a88c189abcda28b98c	f8fee87468d60e19bc12d9a88c189abcda28b98c	ADD
cord-010027-r0tl01kq	6	1	doc_id	doc_id	CD
cord-010027-r0tl01kq	6	2	:	:	:
cord-010027-r0tl01kq	6	3	10027	10027	CD
cord-010027-r0tl01kq	6	4	cord_uid	cord_uid	NNS
cord-010027-r0tl01kq	6	5	:	:	:
cord-010027-r0tl01kq	6	6	r0tl01kq	r0tl01kq	.
cord-010027-r0tl01kq	7	1	nan	nan	NNP
cord-010027-r0tl01kq	8	1	The	the	DT
cord-010027-r0tl01kq	8	2	Christie	Christie	NNP
cord-010027-r0tl01kq	8	3	NHS	NHS	NNP
cord-010027-r0tl01kq	8	4	Foundation	Foundation	NNP
cord-010027-r0tl01kq	8	5	Trust	Trust	NNP
cord-010027-r0tl01kq	8	6	,	,	,
cord-010027-r0tl01kq	8	7	Manchester	Manchester	NNP
cord-010027-r0tl01kq	8	8	,	,	,
cord-010027-r0tl01kq	9	1	UK	UK	NNP
cord-010027-r0tl01kq	9	2	One	one	CD
cord-010027-r0tl01kq	9	3	controversy	controversy	NN
cord-010027-r0tl01kq	9	4	in	in	IN
cord-010027-r0tl01kq	9	5	preparing	prepare	VBG
cord-010027-r0tl01kq	9	6	the	the	DT
cord-010027-r0tl01kq	9	7	RCPath	RCPath	NNP
cord-010027-r0tl01kq	9	8	"	"	``
cord-010027-r0tl01kq	9	9	Dataset	dataset	NN
cord-010027-r0tl01kq	9	10	for	for	IN
cord-010027-r0tl01kq	9	11	tumours	tumour	NNS
cord-010027-r0tl01kq	9	12	of	of	IN
cord-010027-r0tl01kq	9	13	the	the	DT
cord-010027-r0tl01kq	9	14	urinary	urinary	JJ
cord-010027-r0tl01kq	9	15	collecting	collecting	NN
cord-010027-r0tl01kq	9	16	system	system	NN
cord-010027-r0tl01kq	9	17	[	[	-LRB-
cord-010027-r0tl01kq	9	18	2nd	2nd	NNP
cord-010027-r0tl01kq	9	19	edition	edition	NN
cord-010027-r0tl01kq	9	20	]	]	-RRB-
cord-010027-r0tl01kq	9	21	)	)	-RRB-
cord-010027-r0tl01kq	9	22	"	"	''
cord-010027-r0tl01kq	9	23	,	,	,
cord-010027-r0tl01kq	9	24	April	April	NNP
cord-010027-r0tl01kq	9	25	2013	2013	CD
cord-010027-r0tl01kq	9	26	was	be	VBD
cord-010027-r0tl01kq	9	27	which	which	WDT
cord-010027-r0tl01kq	9	28	WHO	who	WP
cord-010027-r0tl01kq	9	29	grading	grading	NN
cord-010027-r0tl01kq	9	30	scheme	scheme	NN
cord-010027-r0tl01kq	9	31	(	(	-LRB-
cord-010027-r0tl01kq	9	32	1973	1973	CD
cord-010027-r0tl01kq	9	33	or	or	CC
cord-010027-r0tl01kq	9	34	2004	2004	CD
cord-010027-r0tl01kq	9	35	)	)	-RRB-
cord-010027-r0tl01kq	9	36	to	to	TO
cord-010027-r0tl01kq	9	37	use	use	VB
cord-010027-r0tl01kq	9	38	for	for	IN
cord-010027-r0tl01kq	9	39	urothelial	urothelial	JJ
cord-010027-r0tl01kq	9	40	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	9	41	.	.	.
cord-010027-r0tl01kq	10	1	Since	since	IN
cord-010027-r0tl01kq	10	2	there	there	EX
cord-010027-r0tl01kq	10	3	is	be	VBZ
cord-010027-r0tl01kq	10	4	a	a	DT
cord-010027-r0tl01kq	10	5	split	split	NN
cord-010027-r0tl01kq	10	6	within	within	IN
cord-010027-r0tl01kq	10	7	grade	grade	NN
cord-010027-r0tl01kq	10	8	2	2	CD
cord-010027-r0tl01kq	10	9	(	(	-LRB-
cord-010027-r0tl01kq	10	10	1973	1973	CD
cord-010027-r0tl01kq	10	11	)	)	-RRB-
cord-010027-r0tl01kq	10	12	between	between	IN
cord-010027-r0tl01kq	10	13	low	low	JJ
cord-010027-r0tl01kq	10	14	grade	grade	NN
cord-010027-r0tl01kq	10	15	&	&	CC
cord-010027-r0tl01kq	10	16	high	high	JJ
cord-010027-r0tl01kq	10	17	grade	grade	NN
cord-010027-r0tl01kq	10	18	,	,	,
cord-010027-r0tl01kq	10	19	use	use	NN
cord-010027-r0tl01kq	10	20	of	of	IN
cord-010027-r0tl01kq	10	21	both	both	DT
cord-010027-r0tl01kq	10	22	schemes	scheme	NNS
cord-010027-r0tl01kq	10	23	in	in	IN
cord-010027-r0tl01kq	10	24	parallel	parallel	NN
cord-010027-r0tl01kq	10	25	was	be	VBD
cord-010027-r0tl01kq	10	26	recommended	recommend	VBN
cord-010027-r0tl01kq	10	27	.	.	.
cord-010027-r0tl01kq	11	1	This	this	DT
cord-010027-r0tl01kq	11	2	has	have	VBZ
cord-010027-r0tl01kq	11	3	the	the	DT
cord-010027-r0tl01kq	11	4	advantage	advantage	NN
cord-010027-r0tl01kq	11	5	of	of	IN
cord-010027-r0tl01kq	11	6	better	well	JJR
cord-010027-r0tl01kq	11	7	indicating	indicate	VBG
cord-010027-r0tl01kq	11	8	where	where	WRB
cord-010027-r0tl01kq	11	9	a	a	DT
cord-010027-r0tl01kq	11	10	particular	particular	JJ
cord-010027-r0tl01kq	11	11	patient	patient	NN
cord-010027-r0tl01kq	11	12	lies	lie	VBZ
cord-010027-r0tl01kq	11	13	in	in	IN
cord-010027-r0tl01kq	11	14	the	the	DT
cord-010027-r0tl01kq	11	15	grading	grading	NN
cord-010027-r0tl01kq	11	16	continuum	continuum	NN
cord-010027-r0tl01kq	11	17	&	&	CC
cord-010027-r0tl01kq	11	18	minimises	minimise	VBZ
cord-010027-r0tl01kq	11	19	the	the	DT
cord-010027-r0tl01kq	11	20	consequences	consequence	NNS
cord-010027-r0tl01kq	11	21	of	of	IN
cord-010027-r0tl01kq	11	22	'	'	``
cord-010027-r0tl01kq	11	23	grading	grading	NN
cord-010027-r0tl01kq	11	24	error	error	NN
cord-010027-r0tl01kq	11	25	'	'	''
cord-010027-r0tl01kq	11	26	for	for	IN
cord-010027-r0tl01kq	11	27	cases	case	NNS
cord-010027-r0tl01kq	11	28	close	close	JJ
cord-010027-r0tl01kq	11	29	to	to	IN
cord-010027-r0tl01kq	11	30	the	the	DT
cord-010027-r0tl01kq	11	31	threshold	threshold	NN
cord-010027-r0tl01kq	11	32	between	between	IN
cord-010027-r0tl01kq	11	33	low	low	JJ
cord-010027-r0tl01kq	11	34	&	&	CC
cord-010027-r0tl01kq	11	35	high	high	JJ
cord-010027-r0tl01kq	11	36	grade	grade	NN
cord-010027-r0tl01kq	11	37	in	in	IN
cord-010027-r0tl01kq	11	38	the	the	DT
cord-010027-r0tl01kq	11	39	2004	2004	CD
cord-010027-r0tl01kq	11	40	scheme	scheme	NN
cord-010027-r0tl01kq	11	41	,	,	,
cord-010027-r0tl01kq	11	42	(	(	-LRB-
cord-010027-r0tl01kq	11	43	a	a	DT
cord-010027-r0tl01kq	11	44	critical	critical	JJ
cord-010027-r0tl01kq	11	45	distinction	distinction	NN
cord-010027-r0tl01kq	11	46	for	for	IN
cord-010027-r0tl01kq	11	47	management	management	NN
cord-010027-r0tl01kq	11	48	if	if	IN
cord-010027-r0tl01kq	11	49	2004	2004	CD
cord-010027-r0tl01kq	11	50	WHO	who	WP
cord-010027-r0tl01kq	11	51	grading	grading	NN
cord-010027-r0tl01kq	11	52	is	be	VBZ
cord-010027-r0tl01kq	11	53	used	use	VBN
cord-010027-r0tl01kq	11	54	in	in	IN
cord-010027-r0tl01kq	11	55	isolation	isolation	NN
cord-010027-r0tl01kq	11	56	)	)	-RRB-
cord-010027-r0tl01kq	11	57	.	.	.
cord-010027-r0tl01kq	12	1	The	the	DT
cord-010027-r0tl01kq	12	2	2015	2015	CD
cord-010027-r0tl01kq	12	3	NICE	nice	JJ
cord-010027-r0tl01kq	12	4	guidance	guidance	NN
cord-010027-r0tl01kq	12	5	on	on	IN
cord-010027-r0tl01kq	12	6	bladder	bladder	NN
cord-010027-r0tl01kq	12	7	cancer	cancer	NN
cord-010027-r0tl01kq	12	8	(	(	-LRB-
cord-010027-r0tl01kq	12	9	http://www.nice.org.uk/guidance/	http://www.nice.org.uk/guidance/	NNP
cord-010027-r0tl01kq	12	10	ng2	ng2	NNP
cord-010027-r0tl01kq	12	11	)	)	-RRB-
cord-010027-r0tl01kq	12	12	incorporates	incorporate	VBZ
cord-010027-r0tl01kq	12	13	risk	risk	NN
cord-010027-r0tl01kq	12	14	stratification	stratification	NN
cord-010027-r0tl01kq	12	15	tables	table	NNS
cord-010027-r0tl01kq	12	16	for	for	IN
cord-010027-r0tl01kq	12	17	Ta	Ta	NNP
cord-010027-r0tl01kq	12	18	/	/	SYM
cord-010027-r0tl01kq	12	19	T1	T1	NNP
cord-010027-r0tl01kq	12	20	bladder	bladder	NN
cord-010027-r0tl01kq	12	21	cancer	cancer	NN
cord-010027-r0tl01kq	12	22	utilizing	utilize	VBG
cord-010027-r0tl01kq	12	23	this	this	DT
cord-010027-r0tl01kq	12	24	parallel	parallel	NN
cord-010027-r0tl01kq	12	25	WHO	who	WP
cord-010027-r0tl01kq	12	26	grading	grade	VBG
cord-010027-r0tl01kq	12	27	recommendation	recommendation	NN
cord-010027-r0tl01kq	12	28	in	in	IN
cord-010027-r0tl01kq	12	29	a	a	DT
cord-010027-r0tl01kq	12	30	multiparameter	multiparameter	NN
cord-010027-r0tl01kq	12	31	formula	formula	NN
cord-010027-r0tl01kq	12	32	that	that	WDT
cord-010027-r0tl01kq	12	33	also	also	RB
cord-010027-r0tl01kq	12	34	considers	consider	VBZ
cord-010027-r0tl01kq	12	35	tumour	tumour	NN
cord-010027-r0tl01kq	12	36	size	size	NN
cord-010027-r0tl01kq	12	37	,	,	,
cord-010027-r0tl01kq	12	38	pT	pt	JJ
cord-010027-r0tl01kq	12	39	classification	classification	NN
cord-010027-r0tl01kq	12	40	and	and	CC
cord-010027-r0tl01kq	12	41	the	the	DT
cord-010027-r0tl01kq	12	42	presence	presence	NN
cord-010027-r0tl01kq	12	43	/	/	SYM
cord-010027-r0tl01kq	12	44	absence	absence	NN
cord-010027-r0tl01kq	12	45	of	of	IN
cord-010027-r0tl01kq	12	46	CIS	CIS	NNP
cord-010027-r0tl01kq	12	47	or	or	CC
cord-010027-r0tl01kq	12	48	aggressive	aggressive	JJ
cord-010027-r0tl01kq	12	49	subtype(s	subtype(s	NN
cord-010027-r0tl01kq	12	50	)	)	-RRB-
cord-010027-r0tl01kq	12	51	.	.	.
cord-010027-r0tl01kq	13	1	Amongst	amongst	IN
cord-010027-r0tl01kq	13	2	the	the	DT
cord-010027-r0tl01kq	13	3	more	more	RBR
cord-010027-r0tl01kq	13	4	aggressive	aggressive	JJ
cord-010027-r0tl01kq	13	5	bladder	bladder	NN
cord-010027-r0tl01kq	13	6	cancer	cancer	NN
cord-010027-r0tl01kq	13	7	subtypes	subtype	NNS
cord-010027-r0tl01kq	13	8	is	be	VBZ
cord-010027-r0tl01kq	13	9	invasive	invasive	JJ
cord-010027-r0tl01kq	13	10	micropapillary	micropapillary	JJ
cord-010027-r0tl01kq	13	11	urothelial	urothelial	JJ
cord-010027-r0tl01kq	13	12	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	13	13	and	and	CC
cord-010027-r0tl01kq	13	14	the	the	DT
cord-010027-r0tl01kq	13	15	nested	nested	JJ
cord-010027-r0tl01kq	13	16	variant	variant	NN
cord-010027-r0tl01kq	13	17	.	.	.
cord-010027-r0tl01kq	14	1	A	a	DT
cord-010027-r0tl01kq	14	2	bladder	bladder	NN
cord-010027-r0tl01kq	14	3	origin	origin	NN
cord-010027-r0tl01kq	14	4	can	can	MD
cord-010027-r0tl01kq	14	5	be	be	VB
cord-010027-r0tl01kq	14	6	difficult	difficult	JJ
cord-010027-r0tl01kq	14	7	to	to	TO
cord-010027-r0tl01kq	14	8	recognise	recognise	VB
cord-010027-r0tl01kq	14	9	at	at	IN
cord-010027-r0tl01kq	14	10	metastatic	metastatic	JJ
cord-010027-r0tl01kq	14	11	sites	site	NNS
cord-010027-r0tl01kq	14	12	,	,	,
cord-010027-r0tl01kq	14	13	especially	especially	RB
cord-010027-r0tl01kq	14	14	for	for	IN
cord-010027-r0tl01kq	14	15	micropapillary	micropapillary	NNP
cord-010027-r0tl01kq	14	16	and	and	CC
cord-010027-r0tl01kq	14	17	discohesive	discohesive	NNP
cord-010027-r0tl01kq	14	18	/	/	SYM
cord-010027-r0tl01kq	14	19	plasmacytoid	plasmacytoid	NN
cord-010027-r0tl01kq	14	20	subtypes	subtype	NNS
cord-010027-r0tl01kq	14	21	.	.	.
cord-010027-r0tl01kq	15	1	Uroplakin	Uroplakin	NNP
cord-010027-r0tl01kq	15	2	II	II	NNP
cord-010027-r0tl01kq	15	3	has	have	VBZ
cord-010027-r0tl01kq	15	4	recently	recently	RB
cord-010027-r0tl01kq	15	5	become	become	VBN
cord-010027-r0tl01kq	15	6	available	available	JJ
cord-010027-r0tl01kq	15	7	,	,	,
cord-010027-r0tl01kq	15	8	is	be	VBZ
cord-010027-r0tl01kq	15	9	more	more	RBR
cord-010027-r0tl01kq	15	10	sensitive	sensitive	JJ
cord-010027-r0tl01kq	15	11	than	than	IN
cord-010027-r0tl01kq	15	12	uroplakin	uroplakin	NNP
cord-010027-r0tl01kq	15	13	III	III	NNP
cord-010027-r0tl01kq	15	14	&	&	CC
cord-010027-r0tl01kq	15	15	may	may	MD
cord-010027-r0tl01kq	15	16	assist	assist	VB
cord-010027-r0tl01kq	15	17	within	within	IN
cord-010027-r0tl01kq	15	18	a	a	DT
cord-010027-r0tl01kq	15	19	panel	panel	NN
cord-010027-r0tl01kq	15	20	.	.	.
cord-010027-r0tl01kq	16	1	Spindle	spindle	JJ
cord-010027-r0tl01kq	16	2	cell	cell	NN
cord-010027-r0tl01kq	16	3	lesions	lesion	NNS
cord-010027-r0tl01kq	16	4	of	of	IN
cord-010027-r0tl01kq	16	5	the	the	DT
cord-010027-r0tl01kq	16	6	bladder	bladder	NN
cord-010027-r0tl01kq	16	7	are	be	VBP
cord-010027-r0tl01kq	16	8	often	often	RB
cord-010027-r0tl01kq	16	9	difficult	difficult	JJ
cord-010027-r0tl01kq	16	10	&	&	CC
cord-010027-r0tl01kq	16	11	loss	loss	NN
cord-010027-r0tl01kq	16	12	of	of	IN
cord-010027-r0tl01kq	16	13	cytokeratin	cytokeratin	NNP
cord-010027-r0tl01kq	16	14	expression	expression	NN
cord-010027-r0tl01kq	16	15	is	be	VBZ
cord-010027-r0tl01kq	16	16	common	common	JJ
cord-010027-r0tl01kq	16	17	in	in	IN
cord-010027-r0tl01kq	16	18	sarcomatoid	sarcomatoid	JJ
cord-010027-r0tl01kq	16	19	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	16	20	.	.	.
cord-010027-r0tl01kq	17	1	There	there	EX
cord-010027-r0tl01kq	17	2	is	be	VBZ
cord-010027-r0tl01kq	17	3	potential	potential	JJ
cord-010027-r0tl01kq	17	4	to	to	TO
cord-010027-r0tl01kq	17	5	mistake	mistake	VB
cord-010027-r0tl01kq	17	6	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	17	7	myofibroblastic	myofibroblastic	JJ
cord-010027-r0tl01kq	17	8	tumour	tumour	NN
cord-010027-r0tl01kq	17	9	for	for	IN
cord-010027-r0tl01kq	17	10	a	a	DT
cord-010027-r0tl01kq	17	11	malignant	malignant	JJ
cord-010027-r0tl01kq	17	12	tumour	tumour	NN
cord-010027-r0tl01kq	17	13	.	.	.
cord-010027-r0tl01kq	18	1	Two	two	CD
cord-010027-r0tl01kq	18	2	molecular	molecular	JJ
cord-010027-r0tl01kq	18	3	pathways	pathway	NNS
cord-010027-r0tl01kq	18	4	for	for	IN
cord-010027-r0tl01kq	18	5	bladder	bladder	NN
cord-010027-r0tl01kq	18	6	cancer	cancer	NN
cord-010027-r0tl01kq	18	7	are	be	VBP
cord-010027-r0tl01kq	18	8	recognised	recognise	VBN
cord-010027-r0tl01kq	18	9	.	.	.
cord-010027-r0tl01kq	19	1	FGFR3	fgfr3	XX
cord-010027-r0tl01kq	20	1	at	at	IN
cord-010027-r0tl01kq	20	2	4p16	4p16	CD
cord-010027-r0tl01kq	20	3	is	be	VBZ
cord-010027-r0tl01kq	20	4	the	the	DT
cord-010027-r0tl01kq	20	5	most	most	RBS
cord-010027-r0tl01kq	20	6	frequently	frequently	RB
cord-010027-r0tl01kq	20	7	mutated	mutate	VBN
cord-010027-r0tl01kq	20	8	oncogene	oncogene	NN
cord-010027-r0tl01kq	20	9	in	in	IN
cord-010027-r0tl01kq	20	10	bladder	bladder	NN
cord-010027-r0tl01kq	20	11	cancer	cancer	NN
cord-010027-r0tl01kq	20	12	&	&	CC
cord-010027-r0tl01kq	20	13	is	be	VBZ
cord-010027-r0tl01kq	20	14	prevalent	prevalent	JJ
cord-010027-r0tl01kq	20	15	in	in	IN
cord-010027-r0tl01kq	20	16	low	low	JJ
cord-010027-r0tl01kq	20	17	grade	grade	NN
cord-010027-r0tl01kq	20	18	papillary	papillary	JJ
cord-010027-r0tl01kq	20	19	tumours	tumour	NNS
cord-010027-r0tl01kq	20	20	.	.	.
cord-010027-r0tl01kq	21	1	p53	p53	NN
cord-010027-r0tl01kq	21	2	loss	loss	NN
cord-010027-r0tl01kq	21	3	of	of	IN
cord-010027-r0tl01kq	21	4	function	function	NN
cord-010027-r0tl01kq	21	5	mutations	mutation	NNS
cord-010027-r0tl01kq	21	6	and	and	CC
cord-010027-r0tl01kq	21	7	loss	loss	NN
cord-010027-r0tl01kq	21	8	of	of	IN
cord-010027-r0tl01kq	21	9	RB1	RB1	NNP
cord-010027-r0tl01kq	21	10	are	be	VBP
cord-010027-r0tl01kq	21	11	prevalent	prevalent	JJ
cord-010027-r0tl01kq	21	12	in	in	IN
cord-010027-r0tl01kq	21	13	CIS	CIS	NNP
cord-010027-r0tl01kq	21	14	.	.	.
cord-010027-r0tl01kq	22	1	No	no	DT
cord-010027-r0tl01kq	22	2	prognostic	prognostic	JJ
cord-010027-r0tl01kq	22	3	molecular	molecular	JJ
cord-010027-r0tl01kq	22	4	test	test	NN
cord-010027-r0tl01kq	22	5	is	be	VBZ
cord-010027-r0tl01kq	22	6	currently	currently	RB
cord-010027-r0tl01kq	22	7	validated	validate	VBN
cord-010027-r0tl01kq	22	8	for	for	IN
cord-010027-r0tl01kq	22	9	clinical	clinical	JJ
cord-010027-r0tl01kq	22	10	use	use	NN
cord-010027-r0tl01kq	22	11	in	in	IN
cord-010027-r0tl01kq	22	12	bladder	bladder	NN
cord-010027-r0tl01kq	22	13	cancer	cancer	NN
cord-010027-r0tl01kq	22	14	,	,	,
cord-010027-r0tl01kq	22	15	though	though	IN
cord-010027-r0tl01kq	22	16	some	some	DT
cord-010027-r0tl01kq	22	17	(	(	-LRB-
cord-010027-r0tl01kq	22	18	e.g.	e.g.	IN
cord-010027-r0tl01kq	22	19	FISH	fish	NN
cord-010027-r0tl01kq	22	20	)	)	-RRB-
cord-010027-r0tl01kq	22	21	are	be	VBP
cord-010027-r0tl01kq	22	22	in	in	IN
cord-010027-r0tl01kq	22	23	use	use	NN
cord-010027-r0tl01kq	22	24	as	as	IN
cord-010027-r0tl01kq	22	25	an	an	DT
cord-010027-r0tl01kq	22	26	adjunct	adjunct	NN
cord-010027-r0tl01kq	22	27	in	in	IN
cord-010027-r0tl01kq	22	28	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	22	29	.	.	.
cord-010027-r0tl01kq	23	1	Indiana	Indiana	NNP
cord-010027-r0tl01kq	23	2	University	University	NNP
cord-010027-r0tl01kq	23	3	School	School	NNP
cord-010027-r0tl01kq	23	4	of	of	IN
cord-010027-r0tl01kq	23	5	Medicine	Medicine	NNP
cord-010027-r0tl01kq	23	6	,	,	,
cord-010027-r0tl01kq	23	7	Indianapolis	Indianapolis	NNP
cord-010027-r0tl01kq	23	8	,	,	,
cord-010027-r0tl01kq	23	9	USA	USA	NNP
cord-010027-r0tl01kq	24	1	Some	some	DT
cord-010027-r0tl01kq	24	2	dogmas	dogma	NNS
cord-010027-r0tl01kq	24	3	in	in	IN
cord-010027-r0tl01kq	24	4	testicular	testicular	NN
cord-010027-r0tl01kq	24	5	pathology	pathology	NN
cord-010027-r0tl01kq	24	6	do	do	VBP
cord-010027-r0tl01kq	24	7	not	not	RB
cord-010027-r0tl01kq	24	8	hold	hold	VB
cord-010027-r0tl01kq	24	9	up	up	RP
cord-010027-r0tl01kq	24	10	to	to	IN
cord-010027-r0tl01kq	24	11	scrutiny	scrutiny	NN
cord-010027-r0tl01kq	24	12	.	.	.
cord-010027-r0tl01kq	25	1	The	the	DT
cord-010027-r0tl01kq	25	2	belief	belief	NN
cord-010027-r0tl01kq	25	3	that	that	IN
cord-010027-r0tl01kq	25	4	all	all	DT
cord-010027-r0tl01kq	25	5	pure	pure	JJ
cord-010027-r0tl01kq	25	6	,	,	,
cord-010027-r0tl01kq	25	7	postpubertal	postpubertal	NNP
cord-010027-r0tl01kq	25	8	teratomas	teratoma	NNS
cord-010027-r0tl01kq	25	9	are	be	VBP
cord-010027-r0tl01kq	25	10	malignant	malignant	JJ
cord-010027-r0tl01kq	25	11	is	be	VBZ
cord-010027-r0tl01kq	25	12	invalid	invalid	JJ
cord-010027-r0tl01kq	25	13	.	.	.
cord-010027-r0tl01kq	26	1	Within	within	IN
cord-010027-r0tl01kq	26	2	this	this	DT
cord-010027-r0tl01kq	26	3	group	group	NN
cord-010027-r0tl01kq	26	4	there	there	EX
cord-010027-r0tl01kq	26	5	is	be	VBZ
cord-010027-r0tl01kq	26	6	a	a	DT
cord-010027-r0tl01kq	26	7	small	small	JJ
cord-010027-r0tl01kq	26	8	subset	subset	NN
cord-010027-r0tl01kq	26	9	that	that	WDT
cord-010027-r0tl01kq	26	10	is	be	VBZ
cord-010027-r0tl01kq	26	11	benign	benign	JJ
cord-010027-r0tl01kq	26	12	;	;	:
cord-010027-r0tl01kq	26	13	these	these	DT
cord-010027-r0tl01kq	26	14	may	may	MD
cord-010027-r0tl01kq	26	15	be	be	VB
cord-010027-r0tl01kq	26	16	divided	divide	VBN
cord-010027-r0tl01kq	26	17	into	into	IN
cord-010027-r0tl01kq	26	18	dermoid	dermoid	JJ
cord-010027-r0tl01kq	26	19	and	and	CC
cord-010027-r0tl01kq	26	20	non	non	JJ
cord-010027-r0tl01kq	26	21	-	-	JJ
cord-010027-r0tl01kq	26	22	dermoid	dermoid	JJ
cord-010027-r0tl01kq	26	23	types	type	NNS
cord-010027-r0tl01kq	26	24	that	that	WDT
cord-010027-r0tl01kq	26	25	,	,	,
cord-010027-r0tl01kq	26	26	however	however	RB
cord-010027-r0tl01kq	26	27	,	,	,
cord-010027-r0tl01kq	26	28	share	share	NN
cord-010027-r0tl01kq	26	29	features	feature	NNS
cord-010027-r0tl01kq	26	30	that	that	WDT
cord-010027-r0tl01kq	26	31	distinguish	distinguish	VBP
cord-010027-r0tl01kq	26	32	them	-PRON-	PRP
cord-010027-r0tl01kq	26	33	from	from	IN
cord-010027-r0tl01kq	26	34	the	the	DT
cord-010027-r0tl01kq	26	35	usual	usual	JJ
cord-010027-r0tl01kq	26	36	teratoma	teratoma	NN
cord-010027-r0tl01kq	26	37	of	of	IN
cord-010027-r0tl01kq	26	38	adults	adult	NNS
cord-010027-r0tl01kq	26	39	.	.	.
cord-010027-r0tl01kq	27	1	These	these	DT
cord-010027-r0tl01kq	27	2	include	include	VBP
cord-010027-r0tl01kq	27	3	absence	absence	NN
cord-010027-r0tl01kq	27	4	of	of	IN
cord-010027-r0tl01kq	27	5	:	:	:
cord-010027-r0tl01kq	27	6	atypia	atypia	NN
cord-010027-r0tl01kq	27	7	,	,	,
cord-010027-r0tl01kq	27	8	regressive	regressive	JJ
cord-010027-r0tl01kq	27	9	parenchymal	parenchymal	NN
cord-010027-r0tl01kq	27	10	changes	change	NNS
cord-010027-r0tl01kq	27	11	,	,	,
cord-010027-r0tl01kq	27	12	intratubular	intratubular	JJ
cord-010027-r0tl01kq	27	13	germ	germ	NN
cord-010027-r0tl01kq	27	14	cell	cell	NN
cord-010027-r0tl01kq	27	15	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	27	16	,	,	,
cord-010027-r0tl01kq	27	17	and	and	CC
cord-010027-r0tl01kq	27	18	i(12p	i(12p	LS
cord-010027-r0tl01kq	27	19	)	)	-RRB-
cord-010027-r0tl01kq	27	20	.	.	.
cord-010027-r0tl01kq	28	1	Also	also	RB
cord-010027-r0tl01kq	28	2	they	-PRON-	PRP
cord-010027-r0tl01kq	28	3	usually	usually	RB
cord-010027-r0tl01kq	28	4	show	show	VBP
cord-010027-r0tl01kq	28	5	organoid	organoid	JJ
cord-010027-r0tl01kq	28	6	arrangements	arrangement	NNS
cord-010027-r0tl01kq	28	7	,	,	,
cord-010027-r0tl01kq	28	8	and	and	CC
cord-010027-r0tl01kq	28	9	prominence	prominence	NN
cord-010027-r0tl01kq	28	10	of	of	IN
cord-010027-r0tl01kq	28	11	ciliated	ciliated	JJ
cord-010027-r0tl01kq	28	12	epithelium	epithelium	NN
cord-010027-r0tl01kq	28	13	,	,	,
cord-010027-r0tl01kq	28	14	squamous	squamous	JJ
cord-010027-r0tl01kq	28	15	cysts	cyst	NNS
cord-010027-r0tl01kq	28	16	and	and	CC
cord-010027-r0tl01kq	28	17	smooth	smooth	JJ
cord-010027-r0tl01kq	28	18	muscle	muscle	NN
cord-010027-r0tl01kq	28	19	.	.	.
cord-010027-r0tl01kq	29	1	Patients	patient	NNS
cord-010027-r0tl01kq	29	2	do	do	VBP
cord-010027-r0tl01kq	29	3	not	not	RB
cord-010027-r0tl01kq	29	4	need	need	VB
cord-010027-r0tl01kq	29	5	further	further	JJ
cord-010027-r0tl01kq	29	6	intervention	intervention	NN
cord-010027-r0tl01kq	29	7	beyond	beyond	IN
cord-010027-r0tl01kq	29	8	excision	excision	NN
cord-010027-r0tl01kq	29	9	sufficient	sufficient	JJ
cord-010027-r0tl01kq	29	10	to	to	TO
cord-010027-r0tl01kq	29	11	establish	establish	VB
cord-010027-r0tl01kq	29	12	the	the	DT
cord-010027-r0tl01kq	29	13	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	29	14	.	.	.
cord-010027-r0tl01kq	30	1	Cases	case	NNS
cord-010027-r0tl01kq	30	2	often	often	RB
cord-010027-r0tl01kq	30	3	interpreted	interpret	VBD
cord-010027-r0tl01kq	30	4	as	as	IN
cord-010027-r0tl01kq	30	5	isolated	isolate	VBN
cord-010027-r0tl01kq	30	6	testicular	testicular	JJ
cord-010027-r0tl01kq	30	7	polyarteritis	polyarteritis	NN
cord-010027-r0tl01kq	30	8	nodosa	nodosa	RB
cord-010027-r0tl01kq	30	9	because	because	IN
cord-010027-r0tl01kq	30	10	of	of	IN
cord-010027-r0tl01kq	30	11	the	the	DT
cord-010027-r0tl01kq	30	12	presence	presence	NN
cord-010027-r0tl01kq	30	13	of	of	IN
cord-010027-r0tl01kq	30	14	fibrinoid	fibrinoid	JJ
cord-010027-r0tl01kq	30	15	vascular	vascular	JJ
cord-010027-r0tl01kq	30	16	necrosis	necrosis	NN
cord-010027-r0tl01kq	30	17	are	be	VBP
cord-010027-r0tl01kq	30	18	mostly	mostly	RB
cord-010027-r0tl01kq	30	19	attributable	attributable	JJ
cord-010027-r0tl01kq	30	20	to	to	IN
cord-010027-r0tl01kq	30	21	chronic	chronic	JJ
cord-010027-r0tl01kq	30	22	,	,	,
cord-010027-r0tl01kq	30	23	intermittent	intermittent	JJ
cord-010027-r0tl01kq	30	24	torsion	torsion	NN
cord-010027-r0tl01kq	30	25	.	.	.
cord-010027-r0tl01kq	31	1	They	-PRON-	PRP
cord-010027-r0tl01kq	31	2	usually	usually	RB
cord-010027-r0tl01kq	31	3	present	present	VBP
cord-010027-r0tl01kq	31	4	as	as	IN
cord-010027-r0tl01kq	31	5	pain	pain	NN
cord-010027-r0tl01kq	31	6	-	-	HYPH
cord-010027-r0tl01kq	31	7	associated	associate	VBN
cord-010027-r0tl01kq	31	8	,	,	,
cord-010027-r0tl01kq	31	9	palpable	palpable	JJ
cord-010027-r0tl01kq	31	10	or	or	CC
cord-010027-r0tl01kq	31	11	ultrasound	ultrasound	NN
cord-010027-r0tl01kq	31	12	-	-	HYPH
cord-010027-r0tl01kq	31	13	detected	detect	VBN
cord-010027-r0tl01kq	31	14	masses	masse	NNS
cord-010027-r0tl01kq	31	15	,	,	,
cord-010027-r0tl01kq	31	16	with	with	IN
cord-010027-r0tl01kq	31	17	the	the	DT
cord-010027-r0tl01kq	31	18	"	"	``
cord-010027-r0tl01kq	31	19	mass	mass	NN
cord-010027-r0tl01kq	31	20	"	"	''
cord-010027-r0tl01kq	31	21	corresponding	correspond	VBG
cord-010027-r0tl01kq	31	22	to	to	IN
cord-010027-r0tl01kq	31	23	infarct	infarct	NN
cord-010027-r0tl01kq	31	24	and/or	and/or	CC
cord-010027-r0tl01kq	31	25	hemorrhage	hemorrhage	NN
cord-010027-r0tl01kq	31	26	.	.	.
cord-010027-r0tl01kq	32	1	There	there	EX
cord-010027-r0tl01kq	32	2	are	be	VBP
cord-010027-r0tl01kq	32	3	associated	associate	VBN
cord-010027-r0tl01kq	32	4	chronic	chronic	JJ
cord-010027-r0tl01kq	32	5	vascular	vascular	JJ
cord-010027-r0tl01kq	32	6	changes	change	NNS
cord-010027-r0tl01kq	32	7	,	,	,
cord-010027-r0tl01kq	32	8	with	with	IN
cord-010027-r0tl01kq	32	9	frequent	frequent	JJ
cord-010027-r0tl01kq	32	10	marked	marked	JJ
cord-010027-r0tl01kq	32	11	intimal	intimal	JJ
cord-010027-r0tl01kq	32	12	hyperplasia	hyperplasia	NN
cord-010027-r0tl01kq	32	13	of	of	IN
cord-010027-r0tl01kq	32	14	arteries	artery	NNS
cord-010027-r0tl01kq	32	15	,	,	,
cord-010027-r0tl01kq	32	16	mural	mural	NN
cord-010027-r0tl01kq	32	17	fibrosis	fibrosis	NN
cord-010027-r0tl01kq	32	18	of	of	IN
cord-010027-r0tl01kq	32	19	veins	vein	NNS
cord-010027-r0tl01kq	32	20	,	,	,
cord-010027-r0tl01kq	32	21	dilated	dilated	JJ
cord-010027-r0tl01kq	32	22	venules	venule	NNS
cord-010027-r0tl01kq	32	23	and	and	CC
cord-010027-r0tl01kq	32	24	arteriolar	arteriolar	JJ
cord-010027-r0tl01kq	32	25	hyalinization	hyalinization	NN
cord-010027-r0tl01kq	32	26	,	,	,
cord-010027-r0tl01kq	32	27	consistent	consistent	JJ
cord-010027-r0tl01kq	32	28	with	with	IN
cord-010027-r0tl01kq	32	29	torsion	torsion	NN
cord-010027-r0tl01kq	32	30	-	-	HYPH
cord-010027-r0tl01kq	32	31	induced	induce	VBN
cord-010027-r0tl01kq	32	32	venous	venous	JJ
cord-010027-r0tl01kq	32	33	outflow	outflow	JJ
cord-010027-r0tl01kq	32	34	obstruction	obstruction	NN
cord-010027-r0tl01kq	32	35	and	and	CC
cord-010027-r0tl01kq	32	36	secondary	secondary	JJ
cord-010027-r0tl01kq	32	37	arterial	arterial	JJ
cord-010027-r0tl01kq	32	38	hypertension	hypertension	NN
cord-010027-r0tl01kq	32	39	.	.	.
cord-010027-r0tl01kq	33	1	These	these	DT
cord-010027-r0tl01kq	33	2	patients	patient	NNS
cord-010027-r0tl01kq	33	3	do	do	VBP
cord-010027-r0tl01kq	33	4	not	not	RB
cord-010027-r0tl01kq	33	5	develop	develop	VB
cord-010027-r0tl01kq	33	6	systemic	systemic	JJ
cord-010027-r0tl01kq	33	7	vasculitis	vasculitis	NN
cord-010027-r0tl01kq	33	8	on	on	IN
cord-010027-r0tl01kq	33	9	follow	follow	NN
cord-010027-r0tl01kq	33	10	-	-	HYPH
cord-010027-r0tl01kq	33	11	up	up	NN
cord-010027-r0tl01kq	33	12	.	.	.
cord-010027-r0tl01kq	34	1	Many	many	JJ
cord-010027-r0tl01kq	34	2	"	"	``
cord-010027-r0tl01kq	34	3	sarcomas	sarcoma	NNS
cord-010027-r0tl01kq	34	4	"	"	''
cord-010027-r0tl01kq	34	5	in	in	IN
cord-010027-r0tl01kq	34	6	patients	patient	NNS
cord-010027-r0tl01kq	34	7	with	with	IN
cord-010027-r0tl01kq	34	8	germ	germ	NN
cord-010027-r0tl01kq	34	9	cell	cell	NN
cord-010027-r0tl01kq	34	10	tumours	tumour	NNS
cord-010027-r0tl01kq	34	11	,	,	,
cord-010027-r0tl01kq	34	12	especially	especially	RB
cord-010027-r0tl01kq	34	13	after	after	IN
cord-010027-r0tl01kq	34	14	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	34	15	,	,	,
cord-010027-r0tl01kq	34	16	are	be	VBP
cord-010027-r0tl01kq	34	17	more	more	RBR
cord-010027-r0tl01kq	34	18	correctly	correctly	RB
cord-010027-r0tl01kq	34	19	regarded	regard	VBN
cord-010027-r0tl01kq	34	20	as	as	IN
cord-010027-r0tl01kq	34	21	sarcomatoid	sarcomatoid	NNP
cord-010027-r0tl01kq	34	22	yolk	yolk	NN
cord-010027-r0tl01kq	34	23	sac	sac	NN
cord-010027-r0tl01kq	34	24	tumours	tumour	NNS
cord-010027-r0tl01kq	34	25	.	.	.
cord-010027-r0tl01kq	35	1	They	-PRON-	PRP
cord-010027-r0tl01kq	35	2	are	be	VBP
cord-010027-r0tl01kq	35	3	reactive	reactive	JJ
cord-010027-r0tl01kq	35	4	for	for	IN
cord-010027-r0tl01kq	35	5	cytokeratin	cytokeratin	NNP
cord-010027-r0tl01kq	35	6	and	and	CC
cord-010027-r0tl01kq	35	7	glypican	glypican	NNP
cord-010027-r0tl01kq	35	8	3	3	CD
cord-010027-r0tl01kq	35	9	.	.	.
cord-010027-r0tl01kq	36	1	They	-PRON-	PRP
cord-010027-r0tl01kq	36	2	often	often	RB
cord-010027-r0tl01kq	36	3	show	show	VBP
cord-010027-r0tl01kq	36	4	characteristic	characteristic	JJ
cord-010027-r0tl01kq	36	5	features	feature	NNS
cord-010027-r0tl01kq	36	6	:	:	:
cord-010027-r0tl01kq	36	7	nodular	nodular	JJ
cord-010027-r0tl01kq	36	8	growth	growth	NN
cord-010027-r0tl01kq	36	9	,	,	,
cord-010027-r0tl01kq	36	10	myxoid	myxoid	NN
cord-010027-r0tl01kq	36	11	and	and	CC
cord-010027-r0tl01kq	36	12	fibrous	fibrous	JJ
cord-010027-r0tl01kq	36	13	stroma	stroma	NN
cord-010027-r0tl01kq	36	14	,	,	,
cord-010027-r0tl01kq	36	15	spindled	spindled	JJ
cord-010027-r0tl01kq	36	16	and	and	CC
cord-010027-r0tl01kq	36	17	epithelioid	epithelioid	NN
cord-010027-r0tl01kq	36	18	cells	cell	NNS
cord-010027-r0tl01kq	36	19	,	,	,
cord-010027-r0tl01kq	36	20	abrupt	abrupt	JJ
cord-010027-r0tl01kq	36	21	changes	change	NNS
cord-010027-r0tl01kq	36	22	in	in	IN
cord-010027-r0tl01kq	36	23	cellularity	cellularity	NN
cord-010027-r0tl01kq	36	24	,	,	,
cord-010027-r0tl01kq	36	25	and	and	CC
cord-010027-r0tl01kq	36	26	tumor	tumor	NN
cord-010027-r0tl01kq	36	27	"	"	''
cord-010027-r0tl01kq	36	28	ringlets	ringlet	NNS
cord-010027-r0tl01kq	36	29	.	.	.
cord-010027-r0tl01kq	37	1	"	"	``
cord-010027-r0tl01kq	37	2	Most	Most	JJS
cord-010027-r0tl01kq	37	3	are	be	VBP
cord-010027-r0tl01kq	37	4	high	high	JJ
cord-010027-r0tl01kq	37	5	grade	grade	NN
cord-010027-r0tl01kq	37	6	and	and	CC
cord-010027-r0tl01kq	37	7	aggressive	aggressive	JJ
cord-010027-r0tl01kq	37	8	.	.	.
cord-010027-r0tl01kq	38	1	Most	most	RBS
cord-010027-r0tl01kq	38	2	regressed	regress	VBN
cord-010027-r0tl01kq	38	3	germ	germ	NN
cord-010027-r0tl01kq	38	4	cell	cell	NN
cord-010027-r0tl01kq	38	5	tumours	tumour	NNS
cord-010027-r0tl01kq	38	6	can	can	MD
cord-010027-r0tl01kq	38	7	be	be	VB
cord-010027-r0tl01kq	38	8	recognized	recognize	VBN
cord-010027-r0tl01kq	38	9	through	through	IN
cord-010027-r0tl01kq	38	10	a	a	DT
cord-010027-r0tl01kq	38	11	combination	combination	NN
cord-010027-r0tl01kq	38	12	of	of	IN
cord-010027-r0tl01kq	38	13	findings	finding	NNS
cord-010027-r0tl01kq	38	14	,	,	,
cord-010027-r0tl01kq	38	15	although	although	IN
cord-010027-r0tl01kq	38	16	the	the	DT
cord-010027-r0tl01kq	38	17	only	only	JJ
cord-010027-r0tl01kq	38	18	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	38	19	ones	one	NNS
cord-010027-r0tl01kq	38	20	are	be	VBP
cord-010027-r0tl01kq	38	21	a	a	DT
cord-010027-r0tl01kq	38	22	scar	scar	NN
cord-010027-r0tl01kq	38	23	with	with	IN
cord-010027-r0tl01kq	38	24	coarse	coarse	JJ
cord-010027-r0tl01kq	38	25	intratubular	intratubular	JJ
cord-010027-r0tl01kq	38	26	calcifications	calcification	NNS
cord-010027-r0tl01kq	38	27	or	or	CC
cord-010027-r0tl01kq	38	28	with	with	IN
cord-010027-r0tl01kq	38	29	intratubular	intratubular	JJ
cord-010027-r0tl01kq	38	30	germ	germ	NN
cord-010027-r0tl01kq	38	31	cell	cell	NN
cord-010027-r0tl01kq	38	32	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	38	33	.	.	.
cord-010027-r0tl01kq	39	1	Alcohol	alcohol	NN
cord-010027-r0tl01kq	39	2	consumption	consumption	NN
cord-010027-r0tl01kq	39	3	has	have	VBZ
cord-010027-r0tl01kq	39	4	doubled	double	VBN
cord-010027-r0tl01kq	39	5	in	in	IN
cord-010027-r0tl01kq	39	6	Ireland	Ireland	NNP
cord-010027-r0tl01kq	39	7	and	and	CC
cord-010027-r0tl01kq	39	8	the	the	DT
cord-010027-r0tl01kq	39	9	UK	UK	NNP
cord-010027-r0tl01kq	39	10	in	in	IN
cord-010027-r0tl01kq	39	11	the	the	DT
cord-010027-r0tl01kq	39	12	last	last	JJ
cord-010027-r0tl01kq	39	13	60	60	CD
cord-010027-r0tl01kq	39	14	years	year	NNS
cord-010027-r0tl01kq	39	15	.	.	.
cord-010027-r0tl01kq	40	1	The	the	DT
cord-010027-r0tl01kq	40	2	causes	cause	NNS
cord-010027-r0tl01kq	40	3	of	of	IN
cord-010027-r0tl01kq	40	4	this	this	DT
cord-010027-r0tl01kq	40	5	increase	increase	NN
cord-010027-r0tl01kq	40	6	include	include	VBP
cord-010027-r0tl01kq	40	7	increased	increase	VBN
cord-010027-r0tl01kq	40	8	affordability	affordability	NN
cord-010027-r0tl01kq	40	9	of	of	IN
cord-010027-r0tl01kq	40	10	alcohol	alcohol	NN
cord-010027-r0tl01kq	40	11	and	and	CC
cord-010027-r0tl01kq	40	12	its	-PRON-	PRP$
cord-010027-r0tl01kq	40	13	widespread	widespread	JJ
cord-010027-r0tl01kq	40	14	availability	availability	NN
cord-010027-r0tl01kq	40	15	.	.	.
cord-010027-r0tl01kq	41	1	As	as	IN
cord-010027-r0tl01kq	41	2	a	a	DT
cord-010027-r0tl01kq	41	3	consequence	consequence	NN
cord-010027-r0tl01kq	41	4	,	,	,
cord-010027-r0tl01kq	41	5	the	the	DT
cord-010027-r0tl01kq	41	6	health	health	NN
cord-010027-r0tl01kq	41	7	harms	harm	VBZ
cord-010027-r0tl01kq	41	8	associated	associate	VBN
cord-010027-r0tl01kq	41	9	with	with	IN
cord-010027-r0tl01kq	41	10	alcohol	alcohol	NN
cord-010027-r0tl01kq	41	11	have	have	VBP
cord-010027-r0tl01kq	41	12	dramatically	dramatically	RB
cord-010027-r0tl01kq	41	13	increased	increase	VBN
cord-010027-r0tl01kq	41	14	.	.	.
cord-010027-r0tl01kq	42	1	Binge	binge	NN
cord-010027-r0tl01kq	42	2	drinking	drinking	NN
cord-010027-r0tl01kq	42	3	and	and	CC
cord-010027-r0tl01kq	42	4	alcohol	alcohol	NN
cord-010027-r0tl01kq	42	5	consumption	consumption	NN
cord-010027-r0tl01kq	42	6	among	among	IN
cord-010027-r0tl01kq	42	7	by	by	IN
cord-010027-r0tl01kq	42	8	women	woman	NNS
cord-010027-r0tl01kq	42	9	have	have	VBP
cord-010027-r0tl01kq	42	10	risen	rise	VBN
cord-010027-r0tl01kq	42	11	especially	especially	RB
cord-010027-r0tl01kq	42	12	dramatically	dramatically	RB
cord-010027-r0tl01kq	42	13	.	.	.
cord-010027-r0tl01kq	43	1	For	for	IN
cord-010027-r0tl01kq	43	2	example	example	NN
cord-010027-r0tl01kq	43	3	,	,	,
cord-010027-r0tl01kq	43	4	the	the	DT
cord-010027-r0tl01kq	43	5	mortality	mortality	NN
cord-010027-r0tl01kq	43	6	from	from	IN
cord-010027-r0tl01kq	43	7	cirrhosis	cirrhosis	NN
cord-010027-r0tl01kq	43	8	has	have	VBZ
cord-010027-r0tl01kq	43	9	doubled	double	VBN
cord-010027-r0tl01kq	43	10	in	in	IN
cord-010027-r0tl01kq	43	11	the	the	DT
cord-010027-r0tl01kq	43	12	last	last	JJ
cord-010027-r0tl01kq	43	13	20	20	CD
cord-010027-r0tl01kq	43	14	years	year	NNS
cord-010027-r0tl01kq	43	15	in	in	IN
cord-010027-r0tl01kq	43	16	both	both	DT
cord-010027-r0tl01kq	43	17	men	man	NNS
cord-010027-r0tl01kq	43	18	and	and	CC
cord-010027-r0tl01kq	43	19	women	woman	NNS
cord-010027-r0tl01kq	43	20	.	.	.
cord-010027-r0tl01kq	44	1	In	in	IN
cord-010027-r0tl01kq	44	2	response	response	NN
cord-010027-r0tl01kq	44	3	to	to	IN
cord-010027-r0tl01kq	44	4	this	this	DT
cord-010027-r0tl01kq	44	5	,	,	,
cord-010027-r0tl01kq	44	6	the	the	DT
cord-010027-r0tl01kq	44	7	medical	medical	JJ
cord-010027-r0tl01kq	44	8	profession	profession	NN
cord-010027-r0tl01kq	44	9	on	on	IN
cord-010027-r0tl01kq	44	10	both	both	DT
cord-010027-r0tl01kq	44	11	islands	island	NNS
cord-010027-r0tl01kq	44	12	have	have	VBP
cord-010027-r0tl01kq	44	13	led	lead	VBN
cord-010027-r0tl01kq	44	14	informal	informal	JJ
cord-010027-r0tl01kq	44	15	and	and	CC
cord-010027-r0tl01kq	44	16	later	later	JJ
cord-010027-r0tl01kq	44	17	formal	formal	JJ
cord-010027-r0tl01kq	44	18	campaigns	campaign	NNS
cord-010027-r0tl01kq	44	19	to	to	TO
cord-010027-r0tl01kq	44	20	encourage	encourage	VB
cord-010027-r0tl01kq	44	21	policy	policy	NN
cord-010027-r0tl01kq	44	22	change	change	NN
cord-010027-r0tl01kq	44	23	regarding	regard	VBG
cord-010027-r0tl01kq	44	24	alcohol	alcohol	NN
cord-010027-r0tl01kq	44	25	at	at	IN
cord-010027-r0tl01kq	44	26	a	a	DT
cord-010027-r0tl01kq	44	27	national	national	JJ
cord-010027-r0tl01kq	44	28	level	level	NN
cord-010027-r0tl01kq	44	29	.	.	.
cord-010027-r0tl01kq	45	1	In	in	IN
cord-010027-r0tl01kq	45	2	Ireland	Ireland	NNP
cord-010027-r0tl01kq	45	3	,	,	,
cord-010027-r0tl01kq	45	4	this	this	DT
cord-010027-r0tl01kq	45	5	was	be	VBD
cord-010027-r0tl01kq	45	6	driven	drive	VBN
cord-010027-r0tl01kq	45	7	by	by	IN
cord-010027-r0tl01kq	45	8	RCPI	RCPI	NNP
cord-010027-r0tl01kq	45	9	.	.	.
cord-010027-r0tl01kq	46	1	The	the	DT
cord-010027-r0tl01kq	46	2	involvement	involvement	NN
cord-010027-r0tl01kq	46	3	of	of	IN
cord-010027-r0tl01kq	46	4	the	the	DT
cord-010027-r0tl01kq	46	5	medical	medical	JJ
cord-010027-r0tl01kq	46	6	profession	profession	NN
cord-010027-r0tl01kq	46	7	has	have	VBZ
cord-010027-r0tl01kq	46	8	had	have	VBN
cord-010027-r0tl01kq	46	9	a	a	DT
cord-010027-r0tl01kq	46	10	powerful	powerful	JJ
cord-010027-r0tl01kq	46	11	influence	influence	NN
cord-010027-r0tl01kq	46	12	,	,	,
cord-010027-r0tl01kq	46	13	as	as	IN
cord-010027-r0tl01kq	46	14	doctors	doctor	NNS
cord-010027-r0tl01kq	46	15	do	do	VBP
cord-010027-r0tl01kq	46	16	not	not	RB
cord-010027-r0tl01kq	46	17	have	have	VB
cord-010027-r0tl01kq	46	18	a	a	DT
cord-010027-r0tl01kq	46	19	conflict	conflict	NN
cord-010027-r0tl01kq	46	20	of	of	IN
cord-010027-r0tl01kq	46	21	interest	interest	NN
cord-010027-r0tl01kq	46	22	in	in	IN
cord-010027-r0tl01kq	46	23	this	this	DT
cord-010027-r0tl01kq	46	24	matter	matter	NN
cord-010027-r0tl01kq	46	25	,	,	,
cord-010027-r0tl01kq	46	26	in	in	IN
cord-010027-r0tl01kq	46	27	contrast	contrast	NN
cord-010027-r0tl01kq	46	28	to	to	IN
cord-010027-r0tl01kq	46	29	the	the	DT
cord-010027-r0tl01kq	46	30	alcohol	alcohol	NN
cord-010027-r0tl01kq	46	31	industry	industry	NN
cord-010027-r0tl01kq	46	32	.	.	.
cord-010027-r0tl01kq	47	1	The	the	DT
cord-010027-r0tl01kq	47	2	policy	policy	NN
cord-010027-r0tl01kq	47	3	changes	change	NNS
cord-010027-r0tl01kq	47	4	advocated	advocate	VBN
cord-010027-r0tl01kq	47	5	include	include	VBP
cord-010027-r0tl01kq	47	6	particularly	particularly	RB
cord-010027-r0tl01kq	47	7	Minimum	Minimum	NNP
cord-010027-r0tl01kq	47	8	Unit	Unit	NNP
cord-010027-r0tl01kq	47	9	Pricing	Pricing	NNP
cord-010027-r0tl01kq	47	10	(	(	-LRB-
cord-010027-r0tl01kq	47	11	MUP	MUP	NNP
cord-010027-r0tl01kq	47	12	)	)	-RRB-
cord-010027-r0tl01kq	47	13	,	,	,
cord-010027-r0tl01kq	47	14	which	which	WDT
cord-010027-r0tl01kq	47	15	has	have	VBZ
cord-010027-r0tl01kq	47	16	been	be	VBN
cord-010027-r0tl01kq	47	17	shown	show	VBN
cord-010027-r0tl01kq	47	18	to	to	TO
cord-010027-r0tl01kq	47	19	be	be	VB
cord-010027-r0tl01kq	47	20	effective	effective	JJ
cord-010027-r0tl01kq	47	21	in	in	IN
cord-010027-r0tl01kq	47	22	reducing	reduce	VBG
cord-010027-r0tl01kq	47	23	alcohol	alcohol	NN
cord-010027-r0tl01kq	47	24	consumption	consumption	NN
cord-010027-r0tl01kq	47	25	,	,	,
cord-010027-r0tl01kq	47	26	alcohol	alcohol	NN
cord-010027-r0tl01kq	47	27	-	-	HYPH
cord-010027-r0tl01kq	47	28	related	relate	VBN
cord-010027-r0tl01kq	47	29	admission	admission	NN
cord-010027-r0tl01kq	47	30	to	to	IN
cord-010027-r0tl01kq	47	31	hospital	hospital	NN
cord-010027-r0tl01kq	47	32	and	and	CC
cord-010027-r0tl01kq	47	33	crime	crime	NN
cord-010027-r0tl01kq	47	34	in	in	IN
cord-010027-r0tl01kq	47	35	Canada	Canada	NNP
cord-010027-r0tl01kq	47	36	.	.	.
cord-010027-r0tl01kq	48	1	Modelling	modelling	NN
cord-010027-r0tl01kq	48	2	of	of	IN
cord-010027-r0tl01kq	48	3	the	the	DT
cord-010027-r0tl01kq	48	4	data	data	NN
cord-010027-r0tl01kq	48	5	suggests	suggest	VBZ
cord-010027-r0tl01kq	48	6	it	-PRON-	PRP
cord-010027-r0tl01kq	48	7	would	would	MD
cord-010027-r0tl01kq	48	8	have	have	VB
cord-010027-r0tl01kq	48	9	similar	similar	JJ
cord-010027-r0tl01kq	48	10	benefits	benefit	NNS
cord-010027-r0tl01kq	48	11	in	in	IN
cord-010027-r0tl01kq	48	12	UK	UK	NNP
cord-010027-r0tl01kq	48	13	and	and	CC
cord-010027-r0tl01kq	48	14	Ireland	Ireland	NNP
cord-010027-r0tl01kq	48	15	.	.	.
cord-010027-r0tl01kq	49	1	This	this	DT
cord-010027-r0tl01kq	49	2	is	be	VBZ
cord-010027-r0tl01kq	49	3	regarded	regard	VBN
cord-010027-r0tl01kq	49	4	as	as	IN
cord-010027-r0tl01kq	49	5	the	the	DT
cord-010027-r0tl01kq	49	6	single	single	JJ
cord-010027-r0tl01kq	49	7	most	most	RBS
cord-010027-r0tl01kq	49	8	important	important	JJ
cord-010027-r0tl01kq	49	9	first	first	JJ
cord-010027-r0tl01kq	49	10	step	step	NN
cord-010027-r0tl01kq	49	11	.	.	.
cord-010027-r0tl01kq	50	1	Other	other	JJ
cord-010027-r0tl01kq	50	2	steps	step	NNS
cord-010027-r0tl01kq	50	3	which	which	WDT
cord-010027-r0tl01kq	50	4	will	will	MD
cord-010027-r0tl01kq	50	5	help	help	VB
cord-010027-r0tl01kq	50	6	include	include	VB
cord-010027-r0tl01kq	50	7	actions	action	NNS
cord-010027-r0tl01kq	50	8	around	around	IN
cord-010027-r0tl01kq	50	9	alcohol	alcohol	NN
cord-010027-r0tl01kq	50	10	labelling	labelling	NN
cord-010027-r0tl01kq	50	11	,	,	,
cord-010027-r0tl01kq	50	12	availability	availability	NN
cord-010027-r0tl01kq	50	13	and	and	CC
cord-010027-r0tl01kq	50	14	breaking	break	VBG
cord-010027-r0tl01kq	50	15	the	the	DT
cord-010027-r0tl01kq	50	16	link	link	NN
cord-010027-r0tl01kq	50	17	between	between	IN
cord-010027-r0tl01kq	50	18	alcohol	alcohol	NN
cord-010027-r0tl01kq	50	19	and	and	CC
cord-010027-r0tl01kq	50	20	sports	sport	NNS
cord-010027-r0tl01kq	50	21	and	and	CC
cord-010027-r0tl01kq	50	22	leisure	leisure	NN
cord-010027-r0tl01kq	50	23	promotion	promotion	NN
cord-010027-r0tl01kq	50	24	.	.	.
cord-010027-r0tl01kq	51	1	Turning	turn	VBG
cord-010027-r0tl01kq	51	2	off	off	RP
cord-010027-r0tl01kq	51	3	the	the	DT
cord-010027-r0tl01kq	51	4	tap	tap	NN
cord-010027-r0tl01kq	51	5	of	of	IN
cord-010027-r0tl01kq	51	6	cheap	cheap	JJ
cord-010027-r0tl01kq	51	7	alcohol	alcohol	NN
cord-010027-r0tl01kq	51	8	will	will	MD
cord-010027-r0tl01kq	51	9	hopefully	hopefully	RB
cord-010027-r0tl01kq	51	10	soon	soon	RB
cord-010027-r0tl01kq	51	11	reduce	reduce	VB
cord-010027-r0tl01kq	51	12	alcohol	alcohol	NN
cord-010027-r0tl01kq	51	13	health	health	NN
cord-010027-r0tl01kq	51	14	harms	harm	NNS
cord-010027-r0tl01kq	51	15	in	in	IN
cord-010027-r0tl01kq	51	16	UK	UK	NNP
cord-010027-r0tl01kq	51	17	and	and	CC
cord-010027-r0tl01kq	51	18	Ireland	Ireland	NNP
cord-010027-r0tl01kq	52	1			.
cord-010027-r0tl01kq	53	1	Barrett	Barrett	NNP
cord-010027-r0tl01kq	53	2	's	's	POS
cord-010027-r0tl01kq	53	3	Oesophagus	Oesophagus	NNP
cord-010027-r0tl01kq	53	4	:	:	:
cord-010027-r0tl01kq	54	1	An	an	DT
cord-010027-r0tl01kq	54	2	Evolving	evolve	VBG
cord-010027-r0tl01kq	54	3	Challenge	challenge	NN
cord-010027-r0tl01kq	54	4	for	for	IN
cord-010027-r0tl01kq	54	5	the	the	DT
cord-010027-r0tl01kq	54	6	Gastroenterologist	gastroenterologist	NN
cord-010027-r0tl01kq	54	7	P	p	NN
cord-010027-r0tl01kq	54	8	DOT	DOT	NNP
cord-010027-r0tl01kq	54	9	O'Toole	O'Toole	NNP
cord-010027-r0tl01kq	54	10	Cost	cost	NN
cord-010027-r0tl01kq	54	11	-	-	HYPH
cord-010027-r0tl01kq	54	12	effective	effective	JJ
cord-010027-r0tl01kq	54	13	surveillance	surveillance	NN
cord-010027-r0tl01kq	54	14	programmes	programme	NNS
cord-010027-r0tl01kq	54	15	for	for	IN
cord-010027-r0tl01kq	54	16	Barrett	Barrett	NNP
cord-010027-r0tl01kq	54	17	's	's	POS
cord-010027-r0tl01kq	54	18	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	54	19	(	(	-LRB-
cord-010027-r0tl01kq	54	20	BO	BO	NNP
cord-010027-r0tl01kq	54	21	)	)	-RRB-
cord-010027-r0tl01kq	54	22	needs	need	VBZ
cord-010027-r0tl01kq	54	23	to	to	TO
cord-010027-r0tl01kq	54	24	be	be	VB
cord-010027-r0tl01kq	54	25	focused	focus	VBN
cord-010027-r0tl01kq	54	26	at	at	IN
cord-010027-r0tl01kq	54	27	risk	risk	NN
cord-010027-r0tl01kq	54	28	groups	group	NNS
cord-010027-r0tl01kq	54	29	.	.	.
cord-010027-r0tl01kq	55	1	It	-PRON-	PRP
cord-010027-r0tl01kq	55	2	is	be	VBZ
cord-010027-r0tl01kq	55	3	not	not	RB
cord-010027-r0tl01kq	55	4	only	only	RB
cord-010027-r0tl01kq	55	5	a	a	DT
cord-010027-r0tl01kq	55	6	question	question	NN
cord-010027-r0tl01kq	55	7	of	of	IN
cord-010027-r0tl01kq	55	8	identifying	identify	VBG
cord-010027-r0tl01kq	55	9	more	more	JJR
cord-010027-r0tl01kq	55	10	individuals	individual	NNS
cord-010027-r0tl01kq	55	11	with	with	IN
cord-010027-r0tl01kq	55	12	BO	BO	NNP
cord-010027-r0tl01kq	55	13	(	(	-LRB-
cord-010027-r0tl01kq	55	14	initial	initial	JJ
cord-010027-r0tl01kq	55	15	screening	screening	NN
cord-010027-r0tl01kq	55	16	)	)	-RRB-
cord-010027-r0tl01kq	55	17	but	but	CC
cord-010027-r0tl01kq	55	18	screening	screening	NN
cord-010027-r0tl01kq	55	19	and	and	CC
cord-010027-r0tl01kq	55	20	subsequent	subsequent	JJ
cord-010027-r0tl01kq	55	21	surveillance	surveillance	NN
cord-010027-r0tl01kq	55	22	has	have	VBZ
cord-010027-r0tl01kq	55	23	to	to	TO
cord-010027-r0tl01kq	55	24	identify	identify	VB
cord-010027-r0tl01kq	55	25	at	at	IN
cord-010027-r0tl01kq	55	26	-	-	HYPH
cord-010027-r0tl01kq	55	27	risk	risk	NN
cord-010027-r0tl01kq	55	28	individuals	individual	NNS
cord-010027-r0tl01kq	55	29	with	with	IN
cord-010027-r0tl01kq	55	30	BO	BO	NNP
cord-010027-r0tl01kq	55	31	who	who	WP
cord-010027-r0tl01kq	55	32	can	can	MD
cord-010027-r0tl01kq	55	33	benefit	benefit	VB
cord-010027-r0tl01kq	55	34	most	most	JJS
cord-010027-r0tl01kq	55	35	from	from	IN
cord-010027-r0tl01kq	55	36	surveillance	surveillance	NN
cord-010027-r0tl01kq	55	37	or	or	CC
cord-010027-r0tl01kq	55	38	therapy	therapy	NN
cord-010027-r0tl01kq	55	39	.	.	.
cord-010027-r0tl01kq	56	1	Advances	advance	NNS
cord-010027-r0tl01kq	56	2	in	in	IN
cord-010027-r0tl01kq	56	3	endoscopic	endoscopic	NNS
cord-010027-r0tl01kq	56	4	imaging	imaging	NN
cord-010027-r0tl01kq	56	5	(	(	-LRB-
cord-010027-r0tl01kq	56	6	high	high	JJ
cord-010027-r0tl01kq	56	7	resolution	resolution	NN
cord-010027-r0tl01kq	56	8	endoscopy	endoscopy	NN
cord-010027-r0tl01kq	56	9	(	(	-LRB-
cord-010027-r0tl01kq	56	10	[	[	-LRB-
cord-010027-r0tl01kq	56	11	HRE	HRE	NNP
cord-010027-r0tl01kq	56	12	]	]	-RRB-
cord-010027-r0tl01kq	56	13	with	with	IN
cord-010027-r0tl01kq	56	14	dye	dye	NN
cord-010027-r0tl01kq	56	15	-	-	HYPH
cord-010027-r0tl01kq	56	16	based	base	VBN
cord-010027-r0tl01kq	56	17	chromoendoscopy	chromoendoscopy	NNP
cord-010027-r0tl01kq	56	18	,	,	,
cord-010027-r0tl01kq	56	19	electronic	electronic	JJ
cord-010027-r0tl01kq	56	20	chromoendoscopy	chromoendoscopy	NNP
cord-010027-r0tl01kq	56	21	,	,	,
cord-010027-r0tl01kq	56	22	and	and	CC
cord-010027-r0tl01kq	56	23	autofluorescence	autofluorescence	NNP
cord-010027-r0tl01kq	56	24	,	,	,
cord-010027-r0tl01kq	56	25	...	...	NFP
cord-010027-r0tl01kq	56	26	)	)	-RRB-
cord-010027-r0tl01kq	56	27	certainly	certainly	RB
cord-010027-r0tl01kq	56	28	prove	prove	VBP
cord-010027-r0tl01kq	56	29	beneficial	beneficial	JJ
cord-010027-r0tl01kq	56	30	in	in	IN
cord-010027-r0tl01kq	56	31	better	well	JJR
cord-010027-r0tl01kq	56	32	detecting	detect	VBG
cord-010027-r0tl01kq	56	33	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	56	34	within	within	IN
cord-010027-r0tl01kq	56	35	known	know	VBN
cord-010027-r0tl01kq	56	36	BO	BO	NNP
cord-010027-r0tl01kq	56	37	and	and	CC
cord-010027-r0tl01kq	56	38	can	can	MD
cord-010027-r0tl01kq	56	39	guide	guide	VB
cord-010027-r0tl01kq	56	40	sampling	sampling	NN
cord-010027-r0tl01kq	56	41	and	and	CC
cord-010027-r0tl01kq	56	42	subsequent	subsequent	JJ
cord-010027-r0tl01kq	56	43	therapy	therapy	NN
cord-010027-r0tl01kq	56	44	.	.	.
cord-010027-r0tl01kq	57	1	Dysplasia	dysplasia	NN
cord-010027-r0tl01kq	57	2	can	can	MD
cord-010027-r0tl01kq	57	3	be	be	VB
cord-010027-r0tl01kq	57	4	patchy	patchy	JJ
cord-010027-r0tl01kq	57	5	and	and	CC
cord-010027-r0tl01kq	57	6	easily	easily	RB
cord-010027-r0tl01kq	57	7	missed	miss	VBN
cord-010027-r0tl01kq	57	8	during	during	IN
cord-010027-r0tl01kq	57	9	routine	routine	JJ
cord-010027-r0tl01kq	57	10	biopsy	biopsy	NN
cord-010027-r0tl01kq	57	11	sampling	sampling	NN
cord-010027-r0tl01kq	57	12	of	of	IN
cord-010027-r0tl01kq	57	13	BO	BO	NNP
cord-010027-r0tl01kq	57	14	and	and	CC
cord-010027-r0tl01kq	57	15	adequate	adequate	JJ
cord-010027-r0tl01kq	57	16	training	training	NN
cord-010027-r0tl01kq	57	17	with	with	IN
cord-010027-r0tl01kq	57	18	high	high	JJ
cord-010027-r0tl01kq	57	19	resolution	resolution	NN
cord-010027-r0tl01kq	57	20	instruments	instrument	NNS
cord-010027-r0tl01kq	57	21	is	be	VBZ
cord-010027-r0tl01kq	57	22	needed	need	VBN
cord-010027-r0tl01kq	57	23	to	to	TO
cord-010027-r0tl01kq	57	24	increase	increase	VB
cord-010027-r0tl01kq	57	25	detection	detection	NN
cord-010027-r0tl01kq	57	26	rates	rate	NNS
cord-010027-r0tl01kq	57	27	.	.	.
cord-010027-r0tl01kq	58	1	Once	once	IN
cord-010027-r0tl01kq	58	2	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	58	3	is	be	VBZ
cord-010027-r0tl01kq	58	4	detected	detect	VBN
cord-010027-r0tl01kq	58	5	,	,	,
cord-010027-r0tl01kq	58	6	endoscopic	endoscopic	JJ
cord-010027-r0tl01kq	58	7	ablation	ablation	NN
cord-010027-r0tl01kq	58	8	is	be	VBZ
cord-010027-r0tl01kq	58	9	recommended	recommend	VBN
cord-010027-r0tl01kq	58	10	.	.	.
cord-010027-r0tl01kq	59	1	Until	until	IN
cord-010027-r0tl01kq	59	2	recently	recently	RB
cord-010027-r0tl01kq	59	3	,	,	,
cord-010027-r0tl01kq	59	4	the	the	DT
cord-010027-r0tl01kq	59	5	standard	standard	JJ
cord-010027-r0tl01kq	59	6	treatment	treatment	NN
cord-010027-r0tl01kq	59	7	for	for	IN
cord-010027-r0tl01kq	59	8	HGD	HGD	NNP
cord-010027-r0tl01kq	59	9	was	be	VBD
cord-010027-r0tl01kq	59	10	oesophagectomy	oesophagectomy	JJ
cord-010027-r0tl01kq	59	11	but	but	CC
cord-010027-r0tl01kq	59	12	endoscopic	endoscopic	JJ
cord-010027-r0tl01kq	59	13	resection	resection	NN
cord-010027-r0tl01kq	59	14	and	and	CC
cord-010027-r0tl01kq	59	15	ablation	ablation	NN
cord-010027-r0tl01kq	59	16	techniques	technique	NNS
cord-010027-r0tl01kq	59	17	are	be	VBP
cord-010027-r0tl01kq	59	18	now	now	RB
cord-010027-r0tl01kq	59	19	available	available	JJ
cord-010027-r0tl01kq	59	20	to	to	TO
cord-010027-r0tl01kq	59	21	eradicate	eradicate	VB
cord-010027-r0tl01kq	59	22	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	59	23	and	and	CC
cord-010027-r0tl01kq	59	24	mucosal	mucosal	JJ
cord-010027-r0tl01kq	59	25	adenocarcinomas	adenocarcinoma	NNS
cord-010027-r0tl01kq	59	26	.	.	.
cord-010027-r0tl01kq	60	1	Resecting	resect	VBG
cord-010027-r0tl01kq	60	2	visible	visible	JJ
cord-010027-r0tl01kq	60	3	lesions	lesion	NNS
cord-010027-r0tl01kq	60	4	(	(	-LRB-
cord-010027-r0tl01kq	60	5	using	use	VBG
cord-010027-r0tl01kq	60	6	endoscopic	endoscopic	JJ
cord-010027-r0tl01kq	60	7	mucosal	mucosal	JJ
cord-010027-r0tl01kq	60	8	resection	resection	NN
cord-010027-r0tl01kq	60	9	[	[	-LRB-
cord-010027-r0tl01kq	60	10	EMR	EMR	NNP
cord-010027-r0tl01kq	60	11	]	]	-RRB-
cord-010027-r0tl01kq	60	12	or	or	CC
cord-010027-r0tl01kq	60	13	endoscopic	endoscopic	JJ
cord-010027-r0tl01kq	60	14	submucosal	submucosal	NN
cord-010027-r0tl01kq	60	15	dissection	dissection	NN
cord-010027-r0tl01kq	60	16	techniques	technique	NNS
cord-010027-r0tl01kq	60	17	)	)	-RRB-
cord-010027-r0tl01kq	60	18	allows	allow	VBZ
cord-010027-r0tl01kq	60	19	full	full	JJ
cord-010027-r0tl01kq	60	20	pathological	pathological	JJ
cord-010027-r0tl01kq	60	21	T	t	NN
cord-010027-r0tl01kq	60	22	staging	staging	NN
cord-010027-r0tl01kq	60	23	.	.	.
cord-010027-r0tl01kq	61	1	When	when	WRB
cord-010027-r0tl01kq	61	2	invasive	invasive	JJ
cord-010027-r0tl01kq	61	3	cancer	cancer	NN
cord-010027-r0tl01kq	61	4	is	be	VBZ
cord-010027-r0tl01kq	61	5	eliminated	eliminate	VBN
cord-010027-r0tl01kq	61	6	at	at	IN
cord-010027-r0tl01kq	61	7	multidisciplinary	multidisciplinary	JJ
cord-010027-r0tl01kq	61	8	review	review	NN
cord-010027-r0tl01kq	61	9	(	(	-LRB-
cord-010027-r0tl01kq	61	10	i.e.	i.e.	FW
cord-010027-r0tl01kq	61	11	,	,	,
cord-010027-r0tl01kq	61	12	purely	purely	RB
cord-010027-r0tl01kq	61	13	mucosal	mucosal	JJ
cord-010027-r0tl01kq	61	14	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	61	15	confirmed	confirm	VBN
cord-010027-r0tl01kq	61	16	with	with	IN
cord-010027-r0tl01kq	61	17	a	a	DT
cord-010027-r0tl01kq	61	18	nodal	nodal	JJ
cord-010027-r0tl01kq	61	19	risk	risk	NN
cord-010027-r0tl01kq	61	20	<	<	XX
cord-010027-r0tl01kq	61	21	2	2	CD
cord-010027-r0tl01kq	61	22	%	%	NN
cord-010027-r0tl01kq	61	23	)	)	-RRB-
cord-010027-r0tl01kq	61	24	,	,	,
cord-010027-r0tl01kq	61	25	further	further	RB
cord-010027-r0tl01kq	61	26	endotherapy	endotherapy	NNP
cord-010027-r0tl01kq	61	27	to	to	TO
cord-010027-r0tl01kq	61	28	ablate	ablate	VB
cord-010027-r0tl01kq	61	29	residual	residual	JJ
cord-010027-r0tl01kq	61	30	metaplasia	metaplasia	NN
cord-010027-r0tl01kq	61	31	in	in	IN
cord-010027-r0tl01kq	61	32	BO	BO	NNP
cord-010027-r0tl01kq	61	33	can	can	MD
cord-010027-r0tl01kq	61	34	be	be	VB
cord-010027-r0tl01kq	61	35	performed	perform	VBN
cord-010027-r0tl01kq	61	36	using	use	VBG
cord-010027-r0tl01kq	61	37	radiofrequency	radiofrequency	NN
cord-010027-r0tl01kq	61	38	ablation	ablation	NN
cord-010027-r0tl01kq	61	39	(	(	-LRB-
cord-010027-r0tl01kq	61	40	RAF	RAF	NNP
cord-010027-r0tl01kq	61	41	)	)	-RRB-
cord-010027-r0tl01kq	61	42	.	.	.
cord-010027-r0tl01kq	62	1	In	in	IN
cord-010027-r0tl01kq	62	2	a	a	DT
cord-010027-r0tl01kq	62	3	tertiary	tertiary	JJ
cord-010027-r0tl01kq	62	4	centre	centre	NN
cord-010027-r0tl01kq	62	5	use	use	NN
cord-010027-r0tl01kq	62	6	of	of	IN
cord-010027-r0tl01kq	62	7	staging	stage	VBG
cord-010027-r0tl01kq	62	8	EMR	EMR	NNP
cord-010027-r0tl01kq	62	9	is	be	VBZ
cord-010027-r0tl01kq	62	10	frequently	frequently	RB
cord-010027-r0tl01kq	62	11	necessary	necessary	JJ
cord-010027-r0tl01kq	62	12	(	(	-LRB-
cord-010027-r0tl01kq	62	13	>	>	NFP
cord-010027-r0tl01kq	62	14	60	60	CD
cord-010027-r0tl01kq	62	15	%	%	NN
cord-010027-r0tl01kq	62	16	)	)	-RRB-
cord-010027-r0tl01kq	62	17	in	in	IN
cord-010027-r0tl01kq	62	18	patients	patient	NNS
cord-010027-r0tl01kq	62	19	referred	refer	VBN
cord-010027-r0tl01kq	62	20	for	for	IN
cord-010027-r0tl01kq	62	21	endotherapy	endotherapy	NNP
cord-010027-r0tl01kq	62	22	and	and	CC
cord-010027-r0tl01kq	62	23	expert	expert	JJ
cord-010027-r0tl01kq	62	24	endoscopy	endoscopy	NN
cord-010027-r0tl01kq	62	25	is	be	VBZ
cord-010027-r0tl01kq	62	26	required	require	VBN
cord-010027-r0tl01kq	62	27	to	to	TO
cord-010027-r0tl01kq	62	28	ensure	ensure	VB
cord-010027-r0tl01kq	62	29	safe	safe	JJ
cord-010027-r0tl01kq	62	30	and	and	CC
cord-010027-r0tl01kq	62	31	complete	complete	JJ
cord-010027-r0tl01kq	62	32	oncological	oncological	JJ
cord-010027-r0tl01kq	62	33	resection	resection	NN
cord-010027-r0tl01kq	62	34	.	.	.
cord-010027-r0tl01kq	63	1	Conversely	conversely	RB
cord-010027-r0tl01kq	63	2	pT1	pt1	JJ
cord-010027-r0tl01kq	63	3	submucosal	submucosal	VB
cord-010027-r0tl01kq	63	4	cancers	cancer	NNS
cord-010027-r0tl01kq	63	5	detected	detect	VBD
cord-010027-r0tl01kq	63	6	following	follow	VBG
cord-010027-r0tl01kq	63	7	EMR	EMR	NNP
cord-010027-r0tl01kq	63	8	are	be	VBP
cord-010027-r0tl01kq	63	9	confidently	confidently	RB
cord-010027-r0tl01kq	63	10	triaged	triage	VBN
cord-010027-r0tl01kq	63	11	for	for	IN
cord-010027-r0tl01kq	63	12	oesophagectomy	oesophagectomy	NN
cord-010027-r0tl01kq	63	13	.	.	.
cord-010027-r0tl01kq	64	1	Combination	combination	NN
cord-010027-r0tl01kq	64	2	of	of	IN
cord-010027-r0tl01kq	64	3	EMR	EMR	NNP
cord-010027-r0tl01kq	64	4	and	and	CC
cord-010027-r0tl01kq	64	5	RFA	RFA	NNP
cord-010027-r0tl01kq	64	6	in	in	IN
cord-010027-r0tl01kq	64	7	expert	expert	JJ
cord-010027-r0tl01kq	64	8	groups	group	NNS
cord-010027-r0tl01kq	64	9	exceeds	exceed	VBZ
cord-010027-r0tl01kq	64	10	>	>	XX
cord-010027-r0tl01kq	64	11	95	95	CD
cord-010027-r0tl01kq	64	12	%	%	NN
cord-010027-r0tl01kq	64	13	for	for	IN
cord-010027-r0tl01kq	64	14	eradication	eradication	NN
cord-010027-r0tl01kq	64	15	of	of	IN
cord-010027-r0tl01kq	64	16	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	64	17	and	and	CC
cord-010027-r0tl01kq	64	18	metaplasia	metaplasia	NN
cord-010027-r0tl01kq	64	19	.	.	.
cord-010027-r0tl01kq	65	1	Adverse	adverse	JJ
cord-010027-r0tl01kq	65	2	events	event	NNS
cord-010027-r0tl01kq	65	3	are	be	VBP
cord-010027-r0tl01kq	65	4	quite	quite	RB
cord-010027-r0tl01kq	65	5	low	low	JJ
cord-010027-r0tl01kq	65	6	(	(	-LRB-
cord-010027-r0tl01kq	65	7	stricture	stricture	NN
cord-010027-r0tl01kq	65	8	form	form	NN
cord-010027-r0tl01kq	65	9	healing	healing	NN
cord-010027-r0tl01kq	65	10	,	,	,
cord-010027-r0tl01kq	65	11	4	4	CD
cord-010027-r0tl01kq	65	12	%	%	NN
cord-010027-r0tl01kq	65	13	;	;	,
cord-010027-r0tl01kq	65	14	self	self	NN
cord-010027-r0tl01kq	65	15	-	-	HYPH
cord-010027-r0tl01kq	65	16	limited	limit	VBN
cord-010027-r0tl01kq	65	17	haemorrhage	haemorrhage	NN
cord-010027-r0tl01kq	65	18	,	,	,
cord-010027-r0tl01kq	65	19	very	very	RB
cord-010027-r0tl01kq	65	20	rare	rare	JJ
cord-010027-r0tl01kq	65	21	perforations	perforation	NNS
cord-010027-r0tl01kq	65	22	...	...	NFP
cord-010027-r0tl01kq	65	23	)	)	-RRB-
cord-010027-r0tl01kq	65	24	and	and	CC
cord-010027-r0tl01kq	65	25	recurrence	recurrence	NN
cord-010027-r0tl01kq	65	26	of	of	IN
cord-010027-r0tl01kq	65	27	BO	BO	NNP
cord-010027-r0tl01kq	65	28	is	be	VBZ
cord-010027-r0tl01kq	65	29	also	also	RB
cord-010027-r0tl01kq	65	30	low	low	JJ
cord-010027-r0tl01kq	65	31	(	(	-LRB-
cord-010027-r0tl01kq	65	32	<	<	NNP
cord-010027-r0tl01kq	65	33	10	10	CD
cord-010027-r0tl01kq	65	34	%	%	NN
cord-010027-r0tl01kq	65	35	at	at	IN
cord-010027-r0tl01kq	65	36	5	5	CD
cord-010027-r0tl01kq	65	37	years	year	NNS
cord-010027-r0tl01kq	65	38	)	)	-RRB-
cord-010027-r0tl01kq	65	39	.	.	.
cord-010027-r0tl01kq	66	1	Careful	careful	JJ
cord-010027-r0tl01kq	66	2	follow	follow	NN
cord-010027-r0tl01kq	66	3	-	-	HYPH
cord-010027-r0tl01kq	66	4	up	up	NN
cord-010027-r0tl01kq	66	5	endoscopies	endoscopy	NNS
cord-010027-r0tl01kq	66	6	is	be	VBZ
cord-010027-r0tl01kq	66	7	necessary	necessary	JJ
cord-010027-r0tl01kq	66	8	at	at	IN
cord-010027-r0tl01kq	66	9	3	3	CD
cord-010027-r0tl01kq	66	10	to	to	TO
cord-010027-r0tl01kq	66	11	6	6	CD
cord-010027-r0tl01kq	66	12	months	month	NNS
cord-010027-r0tl01kq	66	13	initially	initially	RB
cord-010027-r0tl01kq	66	14	;	;	:
cord-010027-r0tl01kq	66	15	intervals	interval	NNS
cord-010027-r0tl01kq	66	16	theerafter	theerafter	NNP
cord-010027-r0tl01kq	66	17	probably	probably	RB
cord-010027-r0tl01kq	66	18	yearly	yearly	RB
cord-010027-r0tl01kq	66	19	.	.	.
cord-010027-r0tl01kq	67	1			.
cord-010027-r0tl01kq	68	1	The	the	DT
cord-010027-r0tl01kq	68	2	Pathologist	Pathologist	NNP
cord-010027-r0tl01kq	68	3	's	's	POS
cord-010027-r0tl01kq	68	4	Role	role	NN
cord-010027-r0tl01kq	68	5	in	in	IN
cord-010027-r0tl01kq	68	6	the	the	DT
cord-010027-r0tl01kq	68	7	Diagnosis	Diagnosis	NNP
cord-010027-r0tl01kq	68	8	and	and	CC
cord-010027-r0tl01kq	68	9	Management	Management	NNP
cord-010027-r0tl01kq	68	10	of	of	IN
cord-010027-r0tl01kq	68	11	Neoplasia	Neoplasia	NNP
cord-010027-r0tl01kq	68	12	in	in	IN
cord-010027-r0tl01kq	68	13	Barrett	Barrett	NNP
cord-010027-r0tl01kq	68	14	's	's	POS
cord-010027-r0tl01kq	68	15	Oesophagus	Oesophagus	NNP
cord-010027-r0tl01kq	68	16	P	p	NN
cord-010027-r0tl01kq	68	17	C	C	NNP
cord-010027-r0tl01kq	68	18	Muldoon	Muldoon	NNP
cord-010027-r0tl01kq	68	19	St.	St.	NNP
cord-010027-r0tl01kq	68	20	James	James	NNP
cord-010027-r0tl01kq	68	21	's	's	POS
cord-010027-r0tl01kq	68	22	Hospital	Hospital	NNP
cord-010027-r0tl01kq	68	23	,	,	,
cord-010027-r0tl01kq	68	24	Dublin	Dublin	NNP
cord-010027-r0tl01kq	68	25	,	,	,
cord-010027-r0tl01kq	68	26	Ireland	Ireland	NNP
cord-010027-r0tl01kq	69	1	The	the	DT
cord-010027-r0tl01kq	69	2	last	last	JJ
cord-010027-r0tl01kq	69	3	decade	decade	NN
cord-010027-r0tl01kq	69	4	has	have	VBZ
cord-010027-r0tl01kq	69	5	seen	see	VBN
cord-010027-r0tl01kq	69	6	a	a	DT
cord-010027-r0tl01kq	69	7	revolution	revolution	NN
cord-010027-r0tl01kq	69	8	in	in	IN
cord-010027-r0tl01kq	69	9	the	the	DT
cord-010027-r0tl01kq	69	10	management	management	NN
cord-010027-r0tl01kq	69	11	of	of	IN
cord-010027-r0tl01kq	69	12	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	69	13	in	in	IN
cord-010027-r0tl01kq	69	14	Barrett	Barrett	NNP
cord-010027-r0tl01kq	69	15	's	's	POS
cord-010027-r0tl01kq	69	16	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	69	17	.	.	.
cord-010027-r0tl01kq	70	1	More	more	RBR
cord-010027-r0tl01kq	70	2	detailed	detailed	JJ
cord-010027-r0tl01kq	70	3	biopsy	biopsy	NN
cord-010027-r0tl01kq	70	4	protocols	protocol	NNS
cord-010027-r0tl01kq	70	5	,	,	,
cord-010027-r0tl01kq	70	6	along	along	IN
cord-010027-r0tl01kq	70	7	with	with	IN
cord-010027-r0tl01kq	70	8	the	the	DT
cord-010027-r0tl01kq	70	9	advent	advent	NN
cord-010027-r0tl01kq	70	10	of	of	IN
cord-010027-r0tl01kq	70	11	sophisticated	sophisticated	JJ
cord-010027-r0tl01kq	70	12	local	local	JJ
cord-010027-r0tl01kq	70	13	resection	resection	NN
cord-010027-r0tl01kq	70	14	and	and	CC
cord-010027-r0tl01kq	70	15	ablation	ablation	NN
cord-010027-r0tl01kq	70	16	techniques	technique	NNS
cord-010027-r0tl01kq	70	17	,	,	,
cord-010027-r0tl01kq	70	18	have	have	VBP
cord-010027-r0tl01kq	70	19	radically	radically	RB
cord-010027-r0tl01kq	70	20	altered	alter	VBN
cord-010027-r0tl01kq	70	21	the	the	DT
cord-010027-r0tl01kq	70	22	management	management	NN
cord-010027-r0tl01kq	70	23	of	of	IN
cord-010027-r0tl01kq	70	24	this	this	DT
cord-010027-r0tl01kq	70	25	expanding	expand	VBG
cord-010027-r0tl01kq	70	26	cohort	cohort	NN
cord-010027-r0tl01kq	70	27	of	of	IN
cord-010027-r0tl01kq	70	28	patients	patient	NNS
cord-010027-r0tl01kq	70	29	.	.	.
cord-010027-r0tl01kq	71	1	These	these	DT
cord-010027-r0tl01kq	71	2	new	new	JJ
cord-010027-r0tl01kq	71	3	treatment	treatment	NN
cord-010027-r0tl01kq	71	4	modalities	modality	NNS
cord-010027-r0tl01kq	71	5	,	,	,
cord-010027-r0tl01kq	71	6	coupled	couple	VBN
cord-010027-r0tl01kq	71	7	with	with	IN
cord-010027-r0tl01kq	71	8	a	a	DT
cord-010027-r0tl01kq	71	9	massive	massive	JJ
cord-010027-r0tl01kq	71	10	increase	increase	NN
cord-010027-r0tl01kq	71	11	in	in	IN
cord-010027-r0tl01kq	71	12	the	the	DT
cord-010027-r0tl01kq	71	13	numbers	number	NNS
cord-010027-r0tl01kq	71	14	of	of	IN
cord-010027-r0tl01kq	71	15	cases	case	NNS
cord-010027-r0tl01kq	71	16	of	of	IN
cord-010027-r0tl01kq	71	17	Barrett	Barrett	NNP
cord-010027-r0tl01kq	71	18	's	's	POS
cord-010027-r0tl01kq	71	19	being	be	VBG
cord-010027-r0tl01kq	71	20	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	71	21	,	,	,
cord-010027-r0tl01kq	71	22	have	have	VBP
cord-010027-r0tl01kq	71	23	significantly	significantly	RB
cord-010027-r0tl01kq	71	24	altered	alter	VBN
cord-010027-r0tl01kq	71	25	the	the	DT
cord-010027-r0tl01kq	71	26	demands	demand	NNS
cord-010027-r0tl01kq	71	27	placed	place	VBN
cord-010027-r0tl01kq	71	28	upon	upon	IN
cord-010027-r0tl01kq	71	29	pathologists	pathologist	NNS
cord-010027-r0tl01kq	71	30	involved	involve	VBN
cord-010027-r0tl01kq	71	31	in	in	IN
cord-010027-r0tl01kq	71	32	this	this	DT
cord-010027-r0tl01kq	71	33	area	area	NN
cord-010027-r0tl01kq	71	34	.	.	.
cord-010027-r0tl01kq	72	1	These	these	DT
cord-010027-r0tl01kq	72	2	changes	change	NNS
cord-010027-r0tl01kq	72	3	have	have	VBP
cord-010027-r0tl01kq	72	4	presented	present	VBN
cord-010027-r0tl01kq	72	5	pathologists	pathologist	NNS
cord-010027-r0tl01kq	72	6	with	with	IN
cord-010027-r0tl01kq	72	7	an	an	DT
cord-010027-r0tl01kq	72	8	opportunity	opportunity	NN
cord-010027-r0tl01kq	72	9	to	to	TO
cord-010027-r0tl01kq	72	10	challenge	challenge	VB
cord-010027-r0tl01kq	72	11	our	-PRON-	PRP$
cord-010027-r0tl01kq	72	12	existing	exist	VBG
cord-010027-r0tl01kq	72	13	practices	practice	NNS
cord-010027-r0tl01kq	72	14	,	,	,
cord-010027-r0tl01kq	72	15	to	to	TO
cord-010027-r0tl01kq	72	16	improve	improve	VB
cord-010027-r0tl01kq	72	17	the	the	DT
cord-010027-r0tl01kq	72	18	reproducibility	reproducibility	NN
cord-010027-r0tl01kq	72	19	of	of	IN
cord-010027-r0tl01kq	72	20	our	-PRON-	PRP$
cord-010027-r0tl01kq	72	21	analysis	analysis	NN
cord-010027-r0tl01kq	72	22	and	and	CC
cord-010027-r0tl01kq	72	23	to	to	TO
cord-010027-r0tl01kq	72	24	increase	increase	VB
cord-010027-r0tl01kq	72	25	the	the	DT
cord-010027-r0tl01kq	72	26	clinical	clinical	JJ
cord-010027-r0tl01kq	72	27	relevance	relevance	NN
cord-010027-r0tl01kq	72	28	of	of	IN
cord-010027-r0tl01kq	72	29	the	the	DT
cord-010027-r0tl01kq	72	30	way	way	NN
cord-010027-r0tl01kq	72	31	in	in	IN
cord-010027-r0tl01kq	72	32	which	which	WDT
cord-010027-r0tl01kq	72	33	we	-PRON-	PRP
cord-010027-r0tl01kq	72	34	report	report	VBP
cord-010027-r0tl01kq	72	35	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	72	36	in	in	IN
cord-010027-r0tl01kq	72	37	this	this	DT
cord-010027-r0tl01kq	72	38	setting	setting	NN
cord-010027-r0tl01kq	72	39	,	,	,
cord-010027-r0tl01kq	72	40	where	where	WRB
cord-010027-r0tl01kq	72	41	the	the	DT
cord-010027-r0tl01kq	72	42	pathologist	pathologist	NN
cord-010027-r0tl01kq	72	43	plays	play	VBZ
cord-010027-r0tl01kq	72	44	a	a	DT
cord-010027-r0tl01kq	72	45	critical	critical	JJ
cord-010027-r0tl01kq	72	46	role	role	NN
cord-010027-r0tl01kq	72	47	in	in	IN
cord-010027-r0tl01kq	72	48	the	the	DT
cord-010027-r0tl01kq	72	49	multidisciplinary	multidisciplinary	JJ
cord-010027-r0tl01kq	72	50	management	management	NN
cord-010027-r0tl01kq	72	51	approach	approach	NN
cord-010027-r0tl01kq	72	52	.	.	.
cord-010027-r0tl01kq	73	1	This	this	DT
cord-010027-r0tl01kq	73	2	talk	talk	NN
cord-010027-r0tl01kq	73	3	aims	aim	VBZ
cord-010027-r0tl01kq	73	4	to	to	TO
cord-010027-r0tl01kq	73	5	outline	outline	VB
cord-010027-r0tl01kq	73	6	a	a	DT
cord-010027-r0tl01kq	73	7	practical	practical	JJ
cord-010027-r0tl01kq	73	8	approach	approach	NN
cord-010027-r0tl01kq	73	9	to	to	IN
cord-010027-r0tl01kq	73	10	the	the	DT
cord-010027-r0tl01kq	73	11	handling	handling	NN
cord-010027-r0tl01kq	73	12	of	of	IN
cord-010027-r0tl01kq	73	13	these	these	DT
cord-010027-r0tl01kq	73	14	specimens	specimen	NNS
cord-010027-r0tl01kq	73	15	and	and	CC
cord-010027-r0tl01kq	73	16	to	to	TO
cord-010027-r0tl01kq	73	17	provide	provide	VB
cord-010027-r0tl01kq	73	18	clear	clear	JJ
cord-010027-r0tl01kq	73	19	guidelines	guideline	NNS
cord-010027-r0tl01kq	73	20	as	as	IN
cord-010027-r0tl01kq	73	21	to	to	IN
cord-010027-r0tl01kq	73	22	how	how	WRB
cord-010027-r0tl01kq	73	23	to	to	TO
cord-010027-r0tl01kq	73	24	report	report	VB
cord-010027-r0tl01kq	73	25	them	-PRON-	PRP
cord-010027-r0tl01kq	73	26	in	in	IN
cord-010027-r0tl01kq	73	27	the	the	DT
cord-010027-r0tl01kq	73	28	most	most	RBS
cord-010027-r0tl01kq	73	29	clinically	clinically	RB
cord-010027-r0tl01kq	73	30	useful	useful	JJ
cord-010027-r0tl01kq	73	31	way	way	NN
cord-010027-r0tl01kq	73	32	.	.	.
cord-010027-r0tl01kq	74	1			NNP
cord-010027-r0tl01kq	74	2	Modern	Modern	NNP
cord-010027-r0tl01kq	74	3	Management	Management	NNP
cord-010027-r0tl01kq	74	4	in	in	IN
cord-010027-r0tl01kq	74	5	IBD	IBD	NNP
cord-010027-r0tl01kq	74	6	P	P	NNP
cord-010027-r0tl01kq	74	7	MWR	MWR	NNP
cord-010027-r0tl01kq	74	8	Vieth	Vieth	NNP
cord-010027-r0tl01kq	74	9	1	1	CD
cord-010027-r0tl01kq	74	10	;	;	:
cord-010027-r0tl01kq	74	11	H	H	NNP
cord-010027-r0tl01kq	74	12	Neumann	Neumann	NNP
cord-010027-r0tl01kq	74	13	2	2	CD
cord-010027-r0tl01kq	74	14	1	1	CD
cord-010027-r0tl01kq	74	15	Klinikum	Klinikum	NNP
cord-010027-r0tl01kq	74	16	Bayreuth	Bayreuth	NNP
cord-010027-r0tl01kq	74	17	,	,	,
cord-010027-r0tl01kq	74	18	Pathology	Pathology	NNP
cord-010027-r0tl01kq	74	19	,	,	,
cord-010027-r0tl01kq	74	20	Bayreuth	Bayreuth	NNP
cord-010027-r0tl01kq	74	21	,	,	,
cord-010027-r0tl01kq	74	22	Germany	Germany	NNP
cord-010027-r0tl01kq	74	23	;	;	:
cord-010027-r0tl01kq	74	24	2	2	CD
cord-010027-r0tl01kq	74	25	University	University	NNP
cord-010027-r0tl01kq	74	26	Hospital	Hospital	NNP
cord-010027-r0tl01kq	74	27	Erlangen	Erlangen	NNP
cord-010027-r0tl01kq	74	28	,	,	,
cord-010027-r0tl01kq	74	29	Medical	Medical	NNP
cord-010027-r0tl01kq	74	30	Clinic	Clinic	NNP
cord-010027-r0tl01kq	74	31	I	-PRON-	PRP
cord-010027-r0tl01kq	74	32	,	,	,
cord-010027-r0tl01kq	74	33	Erlangen	Erlangen	NNP
cord-010027-r0tl01kq	74	34	,	,	,
cord-010027-r0tl01kq	74	35	Germany	Germany	NNP
cord-010027-r0tl01kq	74	36	Ulcerative	ulcerative	JJ
cord-010027-r0tl01kq	74	37	colitis	colitis	NN
cord-010027-r0tl01kq	74	38	and	and	CC
cord-010027-r0tl01kq	74	39	Crohn	Crohn	NNP
cord-010027-r0tl01kq	74	40	's	's	POS
cord-010027-r0tl01kq	74	41	make	make	VB
cord-010027-r0tl01kq	74	42	a	a	DT
cord-010027-r0tl01kq	74	43	distinct	distinct	JJ
cord-010027-r0tl01kq	74	44	histological	histological	JJ
cord-010027-r0tl01kq	74	45	picture	picture	NN
cord-010027-r0tl01kq	74	46	.	.	.
cord-010027-r0tl01kq	75	1	Around	around	IN
cord-010027-r0tl01kq	75	2	80	80	CD
cord-010027-r0tl01kq	75	3	%	%	NN
cord-010027-r0tl01kq	75	4	of	of	IN
cord-010027-r0tl01kq	75	5	an	an	DT
cord-010027-r0tl01kq	75	6	IBD	IBD	NNP
cord-010027-r0tl01kq	75	7	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	75	8	is	be	VBZ
cord-010027-r0tl01kq	75	9	the	the	DT
cord-010027-r0tl01kq	75	10	clinical	clinical	JJ
cord-010027-r0tl01kq	75	11	information	information	NN
cord-010027-r0tl01kq	75	12	and	and	CC
cord-010027-r0tl01kq	75	13	about	about	RB
cord-010027-r0tl01kq	75	14	20	20	CD
cord-010027-r0tl01kq	75	15	%	%	NN
cord-010027-r0tl01kq	75	16	derives	derive	VBZ
cord-010027-r0tl01kq	75	17	from	from	IN
cord-010027-r0tl01kq	75	18	histology	histology	NN
cord-010027-r0tl01kq	75	19	,	,	,
cord-010027-r0tl01kq	75	20	only	only	RB
cord-010027-r0tl01kq	75	21	.	.	.
cord-010027-r0tl01kq	76	1	For	for	IN
cord-010027-r0tl01kq	76	2	routine	routine	JJ
cord-010027-r0tl01kq	76	3	purposes	purpose	NNS
cord-010027-r0tl01kq	76	4	it	-PRON-	PRP
cord-010027-r0tl01kq	76	5	is	be	VBZ
cord-010027-r0tl01kq	76	6	recommendable	recommendable	JJ
cord-010027-r0tl01kq	76	7	in	in	IN
cord-010027-r0tl01kq	76	8	case	case	NN
cord-010027-r0tl01kq	76	9	of	of	IN
cord-010027-r0tl01kq	76	10	a	a	DT
cord-010027-r0tl01kq	76	11	first	first	JJ
cord-010027-r0tl01kq	76	12	manifestation	manifestation	NN
cord-010027-r0tl01kq	76	13	of	of	IN
cord-010027-r0tl01kq	76	14	an	an	DT
cord-010027-r0tl01kq	76	15	IBD	IBD	NNP
cord-010027-r0tl01kq	76	16	to	to	TO
cord-010027-r0tl01kq	76	17	make	make	VB
cord-010027-r0tl01kq	76	18	a	a	DT
cord-010027-r0tl01kq	76	19	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	76	20	such	such	JJ
cord-010027-r0tl01kq	76	21	as	as	IN
cord-010027-r0tl01kq	76	22	:	:	:
cord-010027-r0tl01kq	76	23	"	"	``
cord-010027-r0tl01kq	76	24	picture	picture	NN
cord-010027-r0tl01kq	76	25	of	of	IN
cord-010027-r0tl01kq	76	26	ulcerative	ulcerative	JJ
cord-010027-r0tl01kq	76	27	colitis	colitis	NN
cord-010027-r0tl01kq	76	28	or	or	CC
cord-010027-r0tl01kq	76	29	picture	picture	NN
cord-010027-r0tl01kq	76	30	of	of	IN
cord-010027-r0tl01kq	76	31	crohn	crohn	NNP
cord-010027-r0tl01kq	76	32	's	's	POS
cord-010027-r0tl01kq	76	33	disease	disease	NN
cord-010027-r0tl01kq	76	34	"	"	''
cord-010027-r0tl01kq	76	35	and	and	CC
cord-010027-r0tl01kq	76	36	to	to	TO
cord-010027-r0tl01kq	76	37	recommend	recommend	VB
cord-010027-r0tl01kq	76	38	a	a	DT
cord-010027-r0tl01kq	76	39	follow	follow	NN
cord-010027-r0tl01kq	76	40	-	-	HYPH
cord-010027-r0tl01kq	76	41	up	up	NN
cord-010027-r0tl01kq	76	42	endoscopy	endoscopy	NN
cord-010027-r0tl01kq	76	43	with	with	IN
cord-010027-r0tl01kq	76	44	biopsies	biopsy	NNS
cord-010027-r0tl01kq	76	45	not	not	RB
cord-010027-r0tl01kq	76	46	prior	prior	RB
cord-010027-r0tl01kq	76	47	to	to	IN
cord-010027-r0tl01kq	76	48	8	8	CD
cord-010027-r0tl01kq	76	49	weeks	week	NNS
cord-010027-r0tl01kq	76	50	after	after	IN
cord-010027-r0tl01kq	76	51	the	the	DT
cord-010027-r0tl01kq	76	52	first	first	JJ
cord-010027-r0tl01kq	76	53	endoscopy	endoscopy	NN
cord-010027-r0tl01kq	76	54	and	and	CC
cord-010027-r0tl01kq	76	55	than	than	IN
cord-010027-r0tl01kq	76	56	confirm	confirm	VB
cord-010027-r0tl01kq	76	57	the	the	DT
cord-010027-r0tl01kq	76	58	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	76	59	later	later	RB
cord-010027-r0tl01kq	76	60	to	to	TO
cord-010027-r0tl01kq	76	61	exclude	exclude	VB
cord-010027-r0tl01kq	76	62	mimickers	mimicker	NNS
cord-010027-r0tl01kq	76	63	of	of	IN
cord-010027-r0tl01kq	76	64	IBD	IBD	NNP
cord-010027-r0tl01kq	76	65	.	.	.
cord-010027-r0tl01kq	77	1	In	in	IN
cord-010027-r0tl01kq	77	2	Crohn	Crohn	NNP
cord-010027-r0tl01kq	77	3	's	's	POS
cord-010027-r0tl01kq	77	4	disease	disease	NN
cord-010027-r0tl01kq	77	5	it	-PRON-	PRP
cord-010027-r0tl01kq	77	6	is	be	VBZ
cord-010027-r0tl01kq	77	7	helpful	helpful	JJ
cord-010027-r0tl01kq	77	8	to	to	TO
cord-010027-r0tl01kq	77	9	take	take	VB
cord-010027-r0tl01kq	77	10	biopsies	biopsy	NNS
cord-010027-r0tl01kq	77	11	from	from	IN
cord-010027-r0tl01kq	77	12	the	the	DT
cord-010027-r0tl01kq	77	13	upper	upper	JJ
cord-010027-r0tl01kq	77	14	GI	gi	NN
cord-010027-r0tl01kq	77	15	-	-	HYPH
cord-010027-r0tl01kq	77	16	tract	tract	NN
cord-010027-r0tl01kq	77	17	to	to	TO
cord-010027-r0tl01kq	77	18	get	get	VB
cord-010027-r0tl01kq	77	19	further	further	JJ
cord-010027-r0tl01kq	77	20	hints	hint	NNS
cord-010027-r0tl01kq	77	21	of	of	IN
cord-010027-r0tl01kq	77	22	Crohn	Crohn	NNP
cord-010027-r0tl01kq	77	23	's	's	POS
cord-010027-r0tl01kq	77	24	disease	disease	NN
cord-010027-r0tl01kq	77	25	.	.	.
cord-010027-r0tl01kq	78	1	In	in	IN
cord-010027-r0tl01kq	78	2	case	case	NN
cord-010027-r0tl01kq	78	3	of	of	IN
cord-010027-r0tl01kq	78	4	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	78	5	,	,	,
cord-010027-r0tl01kq	78	6	the	the	DT
cord-010027-r0tl01kq	78	7	guidelines	guideline	NNS
cord-010027-r0tl01kq	78	8	leave	leave	VBP
cord-010027-r0tl01kq	78	9	some	some	DT
cord-010027-r0tl01kq	78	10	room	room	NN
cord-010027-r0tl01kq	78	11	for	for	IN
cord-010027-r0tl01kq	78	12	local	local	JJ
cord-010027-r0tl01kq	78	13	endoscopic	endoscopic	JJ
cord-010027-r0tl01kq	78	14	treatment	treatment	NN
cord-010027-r0tl01kq	78	15	of	of	IN
cord-010027-r0tl01kq	78	16	low	low	JJ
cord-010027-r0tl01kq	78	17	grade	grade	NN
cord-010027-r0tl01kq	78	18	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	78	19	whereas	whereas	IN
cord-010027-r0tl01kq	78	20	high	high	JJ
cord-010027-r0tl01kq	78	21	grade	grade	NN
cord-010027-r0tl01kq	78	22	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	78	23	is	be	VBZ
cord-010027-r0tl01kq	78	24	still	still	RB
cord-010027-r0tl01kq	78	25	seen	see	VBN
cord-010027-r0tl01kq	78	26	as	as	IN
cord-010027-r0tl01kq	78	27	an	an	DT
cord-010027-r0tl01kq	78	28	indication	indication	NN
cord-010027-r0tl01kq	78	29	for	for	IN
cord-010027-r0tl01kq	78	30	operation	operation	NN
cord-010027-r0tl01kq	78	31	since	since	IN
cord-010027-r0tl01kq	78	32	there	there	EX
cord-010027-r0tl01kq	78	33	is	be	VBZ
cord-010027-r0tl01kq	78	34	a	a	DT
cord-010027-r0tl01kq	78	35	high	high	JJ
cord-010027-r0tl01kq	78	36	probability	probability	NN
cord-010027-r0tl01kq	78	37	of	of	IN
cord-010027-r0tl01kq	78	38	detecting	detect	VBG
cord-010027-r0tl01kq	78	39	a	a	DT
cord-010027-r0tl01kq	78	40	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	78	41	in	in	IN
cord-010027-r0tl01kq	78	42	the	the	DT
cord-010027-r0tl01kq	78	43	operation	operation	NN
cord-010027-r0tl01kq	78	44	specimen	specimen	NN
cord-010027-r0tl01kq	78	45	afterwards	afterwards	RB
cord-010027-r0tl01kq	78	46	.	.	.
cord-010027-r0tl01kq	79	1	Operation	operation	NN
cord-010027-r0tl01kq	79	2	means	mean	VBZ
cord-010027-r0tl01kq	79	3	on	on	IN
cord-010027-r0tl01kq	79	4	normal	normal	JJ
cord-010027-r0tl01kq	79	5	complete	complete	JJ
cord-010027-r0tl01kq	79	6	proctocolectomy	proctocolectomy	NN
cord-010027-r0tl01kq	79	7	.	.	.
cord-010027-r0tl01kq	80	1	This	this	DT
cord-010027-r0tl01kq	80	2	has	have	VBZ
cord-010027-r0tl01kq	80	3	been	be	VBN
cord-010027-r0tl01kq	80	4	indivdually	indivdually	RB
cord-010027-r0tl01kq	80	5	questioned	question	VBN
cord-010027-r0tl01kq	80	6	in	in	IN
cord-010027-r0tl01kq	80	7	the	the	DT
cord-010027-r0tl01kq	80	8	last	last	JJ
cord-010027-r0tl01kq	80	9	time	time	NN
cord-010027-r0tl01kq	80	10	.	.	.
cord-010027-r0tl01kq	81	1	There	there	EX
cord-010027-r0tl01kq	81	2	are	be	VBP
cord-010027-r0tl01kq	81	3	exceptions	exception	NNS
cord-010027-r0tl01kq	81	4	for	for	IN
cord-010027-r0tl01kq	81	5	discussing	discuss	VBG
cord-010027-r0tl01kq	81	6	the	the	DT
cord-010027-r0tl01kq	81	7	indication	indication	NN
cord-010027-r0tl01kq	81	8	of	of	IN
cord-010027-r0tl01kq	81	9	an	an	DT
cord-010027-r0tl01kq	81	10	operation	operation	NN
cord-010027-r0tl01kq	81	11	in	in	IN
cord-010027-r0tl01kq	81	12	IBD	IBD	NNP
cord-010027-r0tl01kq	81	13	:	:	:
cord-010027-r0tl01kq	81	14	cases	case	NNS
cord-010027-r0tl01kq	81	15	with	with	IN
cord-010027-r0tl01kq	81	16	numerous	numerous	JJ
cord-010027-r0tl01kq	81	17	pseudopolyps	pseudopolyps	NN
cord-010027-r0tl01kq	81	18	that	that	DT
cord-010027-r0tl01kq	81	19	can	can	MD
cord-010027-r0tl01kq	81	20	not	not	RB
cord-010027-r0tl01kq	81	21	be	be	VB
cord-010027-r0tl01kq	81	22	searched	search	VBN
cord-010027-r0tl01kq	81	23	for	for	IN
cord-010027-r0tl01kq	81	24	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	81	25	,	,	,
cord-010027-r0tl01kq	81	26	low	low	JJ
cord-010027-r0tl01kq	81	27	grade	grade	NN
cord-010027-r0tl01kq	81	28	lesions	lesion	NNS
cord-010027-r0tl01kq	81	29	that	that	WDT
cord-010027-r0tl01kq	81	30	can	can	MD
cord-010027-r0tl01kq	81	31	not	not	RB
cord-010027-r0tl01kq	81	32	be	be	VB
cord-010027-r0tl01kq	81	33	completely	completely	RB
cord-010027-r0tl01kq	81	34	removed	remove	VBN
cord-010027-r0tl01kq	81	35	,	,	,
cord-010027-r0tl01kq	81	36	multiple	multiple	JJ
cord-010027-r0tl01kq	81	37	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	81	38	lesions	lesion	NNS
cord-010027-r0tl01kq	81	39	and	and	CC
cord-010027-r0tl01kq	81	40	unresponsiveness	unresponsiveness	NN
cord-010027-r0tl01kq	81	41	to	to	IN
cord-010027-r0tl01kq	81	42	medical	medical	JJ
cord-010027-r0tl01kq	81	43	treatment	treatment	NN
cord-010027-r0tl01kq	81	44	.	.	.
cord-010027-r0tl01kq	82	1	Operation	operation	NN
cord-010027-r0tl01kq	82	2	and	and	CC
cord-010027-r0tl01kq	82	3	endoscopic	endoscopic	NN
cord-010027-r0tl01kq	82	4	specimen	specimen	NN
cord-010027-r0tl01kq	82	5	in	in	IN
cord-010027-r0tl01kq	82	6	IBD	IBD	NNP
cord-010027-r0tl01kq	82	7	need	need	VBP
cord-010027-r0tl01kq	82	8	a	a	DT
cord-010027-r0tl01kq	82	9	subtile	subtile	JJ
cord-010027-r0tl01kq	82	10	search	search	NN
cord-010027-r0tl01kq	82	11	for	for	IN
cord-010027-r0tl01kq	82	12	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	82	13	lesions	lesion	NNS
cord-010027-r0tl01kq	82	14	.	.	.
cord-010027-r0tl01kq	83	1	A	a	DT
cord-010027-r0tl01kq	83	2	microscope	microscope	NN
cord-010027-r0tl01kq	83	3	with	with	IN
cord-010027-r0tl01kq	83	4	reverse	reverse	JJ
cord-010027-r0tl01kq	83	5	light	light	NN
cord-010027-r0tl01kq	83	6	may	may	MD
cord-010027-r0tl01kq	83	7	help	help	VB
cord-010027-r0tl01kq	83	8	to	to	TO
cord-010027-r0tl01kq	83	9	identify	identify	VB
cord-010027-r0tl01kq	83	10	suspicous	suspicous	JJ
cord-010027-r0tl01kq	83	11	lesions	lesion	NNS
cord-010027-r0tl01kq	83	12	and	and	CC
cord-010027-r0tl01kq	83	13	may	may	MD
cord-010027-r0tl01kq	83	14	help	help	VB
cord-010027-r0tl01kq	83	15	to	to	TO
cord-010027-r0tl01kq	83	16	decide	decide	VB
cord-010027-r0tl01kq	83	17	where	where	WRB
cord-010027-r0tl01kq	83	18	exactely	exactely	RB
cord-010027-r0tl01kq	83	19	to	to	TO
cord-010027-r0tl01kq	83	20	cut	cut	VB
cord-010027-r0tl01kq	83	21	a	a	DT
cord-010027-r0tl01kq	83	22	specimen	specimen	NN
cord-010027-r0tl01kq	83	23	.	.	.
cord-010027-r0tl01kq	84	1	In	in	IN
cord-010027-r0tl01kq	84	2	conclusion	conclusion	NN
cord-010027-r0tl01kq	84	3	a	a	DT
cord-010027-r0tl01kq	84	4	tight	tight	JJ
cord-010027-r0tl01kq	84	5	cooperation	cooperation	NN
cord-010027-r0tl01kq	84	6	between	between	IN
cord-010027-r0tl01kq	84	7	clinical	clinical	JJ
cord-010027-r0tl01kq	84	8	and	and	CC
cord-010027-r0tl01kq	84	9	histopathological	histopathological	JJ
cord-010027-r0tl01kq	84	10	partners	partner	NNS
cord-010027-r0tl01kq	84	11	is	be	VBZ
cord-010027-r0tl01kq	84	12	recommended	recommend	VBN
cord-010027-r0tl01kq	84	13	to	to	TO
cord-010027-r0tl01kq	84	14	reach	reach	VB
cord-010027-r0tl01kq	84	15	a	a	DT
cord-010027-r0tl01kq	84	16	high	high	JJ
cord-010027-r0tl01kq	84	17	standard	standard	NN
cord-010027-r0tl01kq	84	18	for	for	IN
cord-010027-r0tl01kq	84	19	patient	patient	JJ
cord-010027-r0tl01kq	84	20	care	care	NN
cord-010027-r0tl01kq	84	21	.	.	.
cord-010027-r0tl01kq	85	1	Second	second	JJ
cord-010027-r0tl01kq	85	2	opinions	opinion	NNS
cord-010027-r0tl01kq	85	3	may	may	MD
cord-010027-r0tl01kq	85	4	help	help	VB
cord-010027-r0tl01kq	85	5	to	to	TO
cord-010027-r0tl01kq	85	6	achieve	achieve	VB
cord-010027-r0tl01kq	85	7	and	and	CC
cord-010027-r0tl01kq	85	8	fuel	fuel	VB
cord-010027-r0tl01kq	85	9	the	the	DT
cord-010027-r0tl01kq	85	10	own	own	JJ
cord-010027-r0tl01kq	85	11	learning	learning	NN
cord-010027-r0tl01kq	85	12	process	process	NN
cord-010027-r0tl01kq	85	13	esp	esp	RB
cord-010027-r0tl01kq	85	14	.	.	.
cord-010027-r0tl01kq	86	1	in	in	IN
cord-010027-r0tl01kq	86	2	an	an	DT
cord-010027-r0tl01kq	86	3	institution	institution	NN
cord-010027-r0tl01kq	86	4	with	with	IN
cord-010027-r0tl01kq	86	5	a	a	DT
cord-010027-r0tl01kq	86	6	lower	low	JJR
cord-010027-r0tl01kq	86	7	number	number	NN
cord-010027-r0tl01kq	86	8	of	of	IN
cord-010027-r0tl01kq	86	9	IBD	IBD	NNP
cord-010027-r0tl01kq	86	10	patients	patient	NNS
cord-010027-r0tl01kq	86	11	during	during	IN
cord-010027-r0tl01kq	86	12	the	the	DT
cord-010027-r0tl01kq	86	13	year	year	NN
cord-010027-r0tl01kq	86	14	.	.	.
cord-010027-r0tl01kq	87	1	Colorectal	colorectal	JJ
cord-010027-r0tl01kq	87	2	or	or	CC
cord-010027-r0tl01kq	87	3	bowel	bowel	NN
cord-010027-r0tl01kq	87	4	cancer	cancer	NN
cord-010027-r0tl01kq	87	5	screening	screening	NN
cord-010027-r0tl01kq	87	6	(	(	-LRB-
cord-010027-r0tl01kq	87	7	BCS	BCS	NNP
cord-010027-r0tl01kq	87	8	)	)	-RRB-
cord-010027-r0tl01kq	87	9	is	be	VBZ
cord-010027-r0tl01kq	87	10	commonplace	commonplace	JJ
cord-010027-r0tl01kq	87	11	and	and	CC
cord-010027-r0tl01kq	87	12	organised	organise	VBN
cord-010027-r0tl01kq	87	13	national	national	JJ
cord-010027-r0tl01kq	87	14	screening	screening	NN
cord-010027-r0tl01kq	87	15	programmes	programme	NNS
cord-010027-r0tl01kq	87	16	have	have	VBP
cord-010027-r0tl01kq	87	17	been	be	VBN
cord-010027-r0tl01kq	87	18	developed	develop	VBN
cord-010027-r0tl01kq	87	19	in	in	IN
cord-010027-r0tl01kq	87	20	many	many	JJ
cord-010027-r0tl01kq	87	21	countries	country	NNS
cord-010027-r0tl01kq	87	22	,	,	,
cord-010027-r0tl01kq	87	23	most	most	RBS
cord-010027-r0tl01kq	87	24	notably	notably	RB
cord-010027-r0tl01kq	87	25	in	in	IN
cord-010027-r0tl01kq	87	26	western	western	JJ
cord-010027-r0tl01kq	87	27	Europe	Europe	NNP
cord-010027-r0tl01kq	87	28	.	.	.
cord-010027-r0tl01kq	88	1	Traditionally	traditionally	RB
cord-010027-r0tl01kq	88	2	,	,	,
cord-010027-r0tl01kq	88	3	faecal	faecal	JJ
cord-010027-r0tl01kq	88	4	occult	occult	JJ
cord-010027-r0tl01kq	88	5	blood	blood	NN
cord-010027-r0tl01kq	88	6	(	(	-LRB-
cord-010027-r0tl01kq	88	7	FOB	FOB	NNP
cord-010027-r0tl01kq	88	8	)	)	-RRB-
cord-010027-r0tl01kq	88	9	detection	detection	NN
cord-010027-r0tl01kq	88	10	has	have	VBZ
cord-010027-r0tl01kq	88	11	been	be	VBN
cord-010027-r0tl01kq	88	12	the	the	DT
cord-010027-r0tl01kq	88	13	screening	screening	NN
cord-010027-r0tl01kq	88	14	method	method	NN
cord-010027-r0tl01kq	88	15	of	of	IN
cord-010027-r0tl01kq	88	16	choice	choice	NN
cord-010027-r0tl01kq	88	17	,	,	,
cord-010027-r0tl01kq	88	18	those	those	DT
cord-010027-r0tl01kq	88	19	testing	test	VBG
cord-010027-r0tl01kq	88	20	positive	positive	JJ
cord-010027-r0tl01kq	88	21	being	be	VBG
cord-010027-r0tl01kq	88	22	selected	select	VBN
cord-010027-r0tl01kq	88	23	for	for	IN
cord-010027-r0tl01kq	88	24	subsequent	subsequent	JJ
cord-010027-r0tl01kq	88	25	colonoscopy	colonoscopy	NN
cord-010027-r0tl01kq	88	26	,	,	,
cord-010027-r0tl01kq	88	27	but	but	CC
cord-010027-r0tl01kq	88	28	this	this	DT
cord-010027-r0tl01kq	88	29	is	be	VBZ
cord-010027-r0tl01kq	88	30	changing	change	VBG
cord-010027-r0tl01kq	88	31	,	,	,
cord-010027-r0tl01kq	88	32	with	with	IN
cord-010027-r0tl01kq	88	33	alternative	alternative	JJ
cord-010027-r0tl01kq	88	34	or	or	CC
cord-010027-r0tl01kq	88	35	additional	additional	JJ
cord-010027-r0tl01kq	88	36	screening	screening	NN
cord-010027-r0tl01kq	88	37	tests	test	NNS
cord-010027-r0tl01kq	88	38	gaining	gain	VBG
cord-010027-r0tl01kq	88	39	favour	favour	NN
cord-010027-r0tl01kq	88	40	.	.	.
cord-010027-r0tl01kq	89	1	Most	Most	JJS
cord-010027-r0tl01kq	89	2	of	of	IN
cord-010027-r0tl01kq	89	3	the	the	DT
cord-010027-r0tl01kq	89	4	problems	problem	NNS
cord-010027-r0tl01kq	89	5	in	in	IN
cord-010027-r0tl01kq	89	6	BCS	BCS	NNP
cord-010027-r0tl01kq	89	7	pathology	pathology	NN
cord-010027-r0tl01kq	89	8	practice	practice	NN
cord-010027-r0tl01kq	89	9	are	be	VBP
cord-010027-r0tl01kq	89	10	particularly	particularly	RB
cord-010027-r0tl01kq	89	11	related	relate	VBN
cord-010027-r0tl01kq	89	12	to	to	IN
cord-010027-r0tl01kq	89	13	FOB	FOB	NNP
cord-010027-r0tl01kq	89	14	-	-	HYPH
cord-010027-r0tl01kq	89	15	based	base	VBN
cord-010027-r0tl01kq	89	16	screening	screening	NN
cord-010027-r0tl01kq	89	17	programmes	programme	NNS
cord-010027-r0tl01kq	89	18	,	,	,
cord-010027-r0tl01kq	89	19	as	as	IN
cord-010027-r0tl01kq	89	20	these	these	DT
cord-010027-r0tl01kq	89	21	are	be	VBP
cord-010027-r0tl01kq	89	22	enriched	enrich	VBN
cord-010027-r0tl01kq	89	23	for	for	IN
cord-010027-r0tl01kq	89	24	large	large	JJ
cord-010027-r0tl01kq	89	25	,	,	,
cord-010027-r0tl01kq	89	26	bleeding	bleed	VBG
cord-010027-r0tl01kq	89	27	sigmoid	sigmoid	JJ
cord-010027-r0tl01kq	89	28	adenomas	adenoma	NNS
cord-010027-r0tl01kq	89	29	,	,	,
cord-010027-r0tl01kq	89	30	in	in	IN
cord-010027-r0tl01kq	89	31	comparison	comparison	NN
cord-010027-r0tl01kq	89	32	to	to	IN
cord-010027-r0tl01kq	89	33	programmes	programme	NNS
cord-010027-r0tl01kq	89	34	utilising	utilise	VBG
cord-010027-r0tl01kq	89	35	endoscopy	endoscopy	NN
cord-010027-r0tl01kq	89	36	as	as	IN
cord-010027-r0tl01kq	89	37	the	the	DT
cord-010027-r0tl01kq	89	38	primary	primary	JJ
cord-010027-r0tl01kq	89	39	screening	screening	NN
cord-010027-r0tl01kq	89	40	modality	modality	NN
cord-010027-r0tl01kq	89	41	.	.	.
cord-010027-r0tl01kq	90	1	Experience	experience	NN
cord-010027-r0tl01kq	90	2	within	within	IN
cord-010027-r0tl01kq	90	3	the	the	DT
cord-010027-r0tl01kq	90	4	closely	closely	RB
cord-010027-r0tl01kq	90	5	related	relate	VBN
cord-010027-r0tl01kq	90	6	UK	UK	NNP
cord-010027-r0tl01kq	90	7	BCS	BCS	NNP
cord-010027-r0tl01kq	90	8	programmes	programme	NNS
cord-010027-r0tl01kq	90	9	to	to	IN
cord-010027-r0tl01kq	90	10	date	date	NN
cord-010027-r0tl01kq	90	11	has	have	VBZ
cord-010027-r0tl01kq	90	12	yielded	yield	VBN
cord-010027-r0tl01kq	90	13	several	several	JJ
cord-010027-r0tl01kq	90	14	recurring	recur	VBG
cord-010027-r0tl01kq	90	15	problems	problem	NNS
cord-010027-r0tl01kq	90	16	:	:	:
cord-010027-r0tl01kq	90	17	the	the	DT
cord-010027-r0tl01kq	90	18	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	90	19	of	of	IN
cord-010027-r0tl01kq	90	20	stage	stage	NN
cord-010027-r0tl01kq	90	21	pT1	pT1	VBN
cord-010027-r0tl01kq	90	22	or	or	CC
cord-010027-r0tl01kq	90	23	'	'	``
cord-010027-r0tl01kq	90	24	polyp	polyp	NN
cord-010027-r0tl01kq	90	25	'	'	''
cord-010027-r0tl01kq	90	26	cancers	cancer	NNS
cord-010027-r0tl01kq	90	27	,	,	,
cord-010027-r0tl01kq	90	28	in	in	IN
cord-010027-r0tl01kq	90	29	particular	particular	JJ
cord-010027-r0tl01kq	90	30	distinguishing	distinguish	VBG
cord-010027-r0tl01kq	90	31	common	common	JJ
cord-010027-r0tl01kq	90	32	epithelial	epithelial	JJ
cord-010027-r0tl01kq	90	33	misplacement	misplacement	NN
cord-010027-r0tl01kq	90	34	from	from	IN
cord-010027-r0tl01kq	90	35	'	'	``
cord-010027-r0tl01kq	90	36	true	true	JJ
cord-010027-r0tl01kq	90	37	'	'	''
cord-010027-r0tl01kq	90	38	invasion	invasion	NN
cord-010027-r0tl01kq	90	39	;	;	:
cord-010027-r0tl01kq	90	40	the	the	DT
cord-010027-r0tl01kq	90	41	management	management	NN
cord-010027-r0tl01kq	90	42	of	of	IN
cord-010027-r0tl01kq	90	43	stage	stage	NN
cord-010027-r0tl01kq	90	44	pT1	pT1	VBN
cord-010027-r0tl01kq	90	45	cancers	cancer	NNS
cord-010027-r0tl01kq	90	46	,	,	,
cord-010027-r0tl01kq	90	47	in	in	IN
cord-010027-r0tl01kq	90	48	relation	relation	NN
cord-010027-r0tl01kq	90	49	to	to	IN
cord-010027-r0tl01kq	90	50	indications	indication	NNS
cord-010027-r0tl01kq	90	51	for	for	IN
cord-010027-r0tl01kq	90	52	surgical	surgical	JJ
cord-010027-r0tl01kq	90	53	intervention	intervention	NN
cord-010027-r0tl01kq	90	54	after	after	IN
cord-010027-r0tl01kq	90	55	such	such	PDT
cord-010027-r0tl01kq	90	56	a	a	DT
cord-010027-r0tl01kq	90	57	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	90	58	;	;	:
cord-010027-r0tl01kq	90	59	and	and	CC
cord-010027-r0tl01kq	90	60	the	the	DT
cord-010027-r0tl01kq	90	61	minimum	minimum	JJ
cord-010027-r0tl01kq	90	62	criteria	criterion	NNS
cord-010027-r0tl01kq	90	63	for	for	IN
cord-010027-r0tl01kq	90	64	a	a	DT
cord-010027-r0tl01kq	90	65	biopsy	biopsy	JJ
cord-010027-r0tl01kq	90	66	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	90	67	of	of	IN
cord-010027-r0tl01kq	90	68	colorectal	colorectal	JJ
cord-010027-r0tl01kq	90	69	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	90	70	.	.	.
cord-010027-r0tl01kq	91	1	These	these	DT
cord-010027-r0tl01kq	91	2	issues	issue	NNS
cord-010027-r0tl01kq	91	3	will	will	MD
cord-010027-r0tl01kq	91	4	be	be	VB
cord-010027-r0tl01kq	91	5	discussed	discuss	VBN
cord-010027-r0tl01kq	91	6	with	with	IN
cord-010027-r0tl01kq	91	7	illustrative	illustrative	JJ
cord-010027-r0tl01kq	91	8	examples	example	NNS
cord-010027-r0tl01kq	91	9	,	,	,
cord-010027-r0tl01kq	91	10	along	along	IN
cord-010027-r0tl01kq	91	11	with	with	IN
cord-010027-r0tl01kq	91	12	the	the	DT
cord-010027-r0tl01kq	91	13	somewhat	somewhat	RB
cord-010027-r0tl01kq	91	14	more	more	RBR
cord-010027-r0tl01kq	91	15	mundane	mundane	JJ
cord-010027-r0tl01kq	91	16	but	but	CC
cord-010027-r0tl01kq	91	17	highly	highly	RB
cord-010027-r0tl01kq	91	18	important	important	JJ
cord-010027-r0tl01kq	91	19	practical	practical	JJ
cord-010027-r0tl01kq	91	20	issue	issue	NN
cord-010027-r0tl01kq	91	21	of	of	IN
cord-010027-r0tl01kq	91	22	measuring	measure	VBG
cord-010027-r0tl01kq	91	23	various	various	JJ
cord-010027-r0tl01kq	91	24	parameters	parameter	NNS
cord-010027-r0tl01kq	91	25	related	relate	VBN
cord-010027-r0tl01kq	91	26	to	to	IN
cord-010027-r0tl01kq	91	27	BCS	BCS	NNP
cord-010027-r0tl01kq	91	28	pathology	pathology	NN
cord-010027-r0tl01kq	91	29	.	.	.
cord-010027-r0tl01kq	92	1	The	the	DT
cord-010027-r0tl01kq	92	2	importance	importance	NN
cord-010027-r0tl01kq	92	3	of	of	IN
cord-010027-r0tl01kq	92	4	quality	quality	NN
cord-010027-r0tl01kq	92	5	assurance	assurance	NN
cord-010027-r0tl01kq	92	6	measures	measure	NNS
cord-010027-r0tl01kq	92	7	to	to	TO
cord-010027-r0tl01kq	92	8	ensure	ensure	VB
cord-010027-r0tl01kq	92	9	high	high	JJ
cord-010027-r0tl01kq	92	10	standards	standard	NNS
cord-010027-r0tl01kq	92	11	within	within	IN
cord-010027-r0tl01kq	92	12	BCS	BCS	NNP
cord-010027-r0tl01kq	92	13	pathology	pathology	NN
cord-010027-r0tl01kq	92	14	is	be	VBZ
cord-010027-r0tl01kq	92	15	emphasised	emphasise	VBN
cord-010027-r0tl01kq	92	16	.	.	.
cord-010027-r0tl01kq	93	1	With	with	IN
cord-010027-r0tl01kq	93	2	the	the	DT
cord-010027-r0tl01kq	93	3	introduction	introduction	NN
cord-010027-r0tl01kq	93	4	of	of	IN
cord-010027-r0tl01kq	93	5	colorectal	colorectal	JJ
cord-010027-r0tl01kq	93	6	cancer	cancer	NN
cord-010027-r0tl01kq	93	7	screening	screening	NN
cord-010027-r0tl01kq	93	8	in	in	IN
cord-010027-r0tl01kq	93	9	various	various	JJ
cord-010027-r0tl01kq	93	10	countries	country	NNS
cord-010027-r0tl01kq	93	11	of	of	IN
cord-010027-r0tl01kq	93	12	the	the	DT
cord-010027-r0tl01kq	93	13	EU	EU	NNP
cord-010027-r0tl01kq	93	14	there	there	EX
cord-010027-r0tl01kq	93	15	is	be	VBZ
cord-010027-r0tl01kq	93	16	a	a	DT
cord-010027-r0tl01kq	93	17	sharp	sharp	JJ
cord-010027-r0tl01kq	93	18	increase	increase	NN
cord-010027-r0tl01kq	93	19	in	in	IN
cord-010027-r0tl01kq	93	20	the	the	DT
cord-010027-r0tl01kq	93	21	incidence	incidence	NN
cord-010027-r0tl01kq	93	22	of	of	IN
cord-010027-r0tl01kq	93	23	early	early	JJ
cord-010027-r0tl01kq	93	24	colorectal	colorectal	JJ
cord-010027-r0tl01kq	93	25	cancer	cancer	NN
cord-010027-r0tl01kq	93	26	.	.	.
cord-010027-r0tl01kq	94	1	A	a	DT
cord-010027-r0tl01kq	94	2	significant	significant	JJ
cord-010027-r0tl01kq	94	3	part	part	NN
cord-010027-r0tl01kq	94	4	of	of	IN
cord-010027-r0tl01kq	94	5	these	these	DT
cord-010027-r0tl01kq	94	6	early	early	JJ
cord-010027-r0tl01kq	94	7	tumours	tumour	NNS
cord-010027-r0tl01kq	94	8	presents	present	VBZ
cord-010027-r0tl01kq	94	9	in	in	IN
cord-010027-r0tl01kq	94	10	a	a	DT
cord-010027-r0tl01kq	94	11	pedunculated	pedunculated	JJ
cord-010027-r0tl01kq	94	12	polyp	polyp	NN
cord-010027-r0tl01kq	94	13	.	.	.
cord-010027-r0tl01kq	95	1	In	in	IN
cord-010027-r0tl01kq	95	2	most	most	JJS
cord-010027-r0tl01kq	95	3	cases	case	NNS
cord-010027-r0tl01kq	95	4	,	,	,
cord-010027-r0tl01kq	95	5	these	these	DT
cord-010027-r0tl01kq	95	6	carcinomas	carcinoma	NNS
cord-010027-r0tl01kq	95	7	are	be	VBP
cord-010027-r0tl01kq	95	8	already	already	RB
cord-010027-r0tl01kq	95	9	completely	completely	RB
cord-010027-r0tl01kq	95	10	removed	remove	VBN
cord-010027-r0tl01kq	95	11	by	by	IN
cord-010027-r0tl01kq	95	12	polypectomy	polypectomy	NN
cord-010027-r0tl01kq	95	13	.	.	.
cord-010027-r0tl01kq	96	1	Classic	classic	JJ
cord-010027-r0tl01kq	96	2	risk	risk	NN
cord-010027-r0tl01kq	96	3	factors	factor	NNS
cord-010027-r0tl01kq	96	4	that	that	WDT
cord-010027-r0tl01kq	96	5	suggest	suggest	VBP
cord-010027-r0tl01kq	96	6	a	a	DT
cord-010027-r0tl01kq	96	7	high	high	JJ
cord-010027-r0tl01kq	96	8	risk	risk	NN
cord-010027-r0tl01kq	96	9	for	for	IN
cord-010027-r0tl01kq	96	10	lymph	lymph	NN
cord-010027-r0tl01kq	96	11	node	node	NN
cord-010027-r0tl01kq	96	12	metastases	metastasis	NNS
cord-010027-r0tl01kq	96	13	include	include	VBP
cord-010027-r0tl01kq	96	14	Haggitt	Haggitt	NNP
cord-010027-r0tl01kq	96	15	level	level	NN
cord-010027-r0tl01kq	96	16	4	4	CD
cord-010027-r0tl01kq	96	17	,	,	,
cord-010027-r0tl01kq	96	18	positive	positive	JJ
cord-010027-r0tl01kq	96	19	resection	resection	NN
cord-010027-r0tl01kq	96	20	margins	margin	NNS
cord-010027-r0tl01kq	96	21	,	,	,
cord-010027-r0tl01kq	96	22	poor	poor	JJ
cord-010027-r0tl01kq	96	23	differentiation	differentiation	NN
cord-010027-r0tl01kq	96	24	and	and	CC
cord-010027-r0tl01kq	96	25	lymphatic	lymphatic	JJ
cord-010027-r0tl01kq	96	26	or	or	CC
cord-010027-r0tl01kq	96	27	vascular	vascular	JJ
cord-010027-r0tl01kq	96	28	invasion	invasion	NN
cord-010027-r0tl01kq	96	29	.	.	.
cord-010027-r0tl01kq	97	1	However	however	RB
cord-010027-r0tl01kq	97	2	,	,	,
cord-010027-r0tl01kq	97	3	the	the	DT
cord-010027-r0tl01kq	97	4	evidence	evidence	NN
cord-010027-r0tl01kq	97	5	is	be	VBZ
cord-010027-r0tl01kq	97	6	rather	rather	RB
cord-010027-r0tl01kq	97	7	thin	thin	JJ
cord-010027-r0tl01kq	97	8	.	.	.
cord-010027-r0tl01kq	98	1	Most	Most	JJS
cord-010027-r0tl01kq	98	2	pT1	pt1	JJ
cord-010027-r0tl01kq	98	3	studies	study	NNS
cord-010027-r0tl01kq	98	4	are	be	VBP
cord-010027-r0tl01kq	98	5	performed	perform	VBN
cord-010027-r0tl01kq	98	6	on	on	IN
cord-010027-r0tl01kq	98	7	sessile	sessile	JJ
cord-010027-r0tl01kq	98	8	polyps	polyp	NNS
cord-010027-r0tl01kq	98	9	.	.	.
cord-010027-r0tl01kq	99	1	Risk	risk	NN
cord-010027-r0tl01kq	99	2	factors	factor	NNS
cord-010027-r0tl01kq	99	3	are	be	VBP
cord-010027-r0tl01kq	99	4	more	more	RBR
cord-010027-r0tl01kq	99	5	firmly	firmly	RB
cord-010027-r0tl01kq	99	6	established	establish	VBN
cord-010027-r0tl01kq	99	7	and	and	CC
cord-010027-r0tl01kq	99	8	include	include	VBP
cord-010027-r0tl01kq	99	9	differentiation	differentiation	NN
cord-010027-r0tl01kq	99	10	grade	grade	NN
cord-010027-r0tl01kq	99	11	,	,	,
cord-010027-r0tl01kq	99	12	lymphatic	lymphatic	JJ
cord-010027-r0tl01kq	99	13	invasion	invasion	NN
cord-010027-r0tl01kq	99	14	,	,	,
cord-010027-r0tl01kq	99	15	Kikuchi	Kikuchi	NNP
cord-010027-r0tl01kq	99	16	level	level	NN
cord-010027-r0tl01kq	99	17	sm3	sm3	NNP
cord-010027-r0tl01kq	99	18	or	or	CC
cord-010027-r0tl01kq	99	19	the	the	DT
cord-010027-r0tl01kq	99	20	presence	presence	NN
cord-010027-r0tl01kq	99	21	of	of	IN
cord-010027-r0tl01kq	99	22	budding	bud	VBG
cord-010027-r0tl01kq	99	23	.	.	.
cord-010027-r0tl01kq	100	1	However	however	RB
cord-010027-r0tl01kq	100	2	,	,	,
cord-010027-r0tl01kq	100	3	for	for	IN
cord-010027-r0tl01kq	100	4	a	a	DT
cord-010027-r0tl01kq	100	5	clinical	clinical	JJ
cord-010027-r0tl01kq	100	6	useful	useful	JJ
cord-010027-r0tl01kq	100	7	decision	decision	NN
cord-010027-r0tl01kq	100	8	model	model	NN
cord-010027-r0tl01kq	100	9	,	,	,
cord-010027-r0tl01kq	100	10	we	-PRON-	PRP
cord-010027-r0tl01kq	100	11	will	will	MD
cord-010027-r0tl01kq	100	12	need	need	VB
cord-010027-r0tl01kq	100	13	an	an	DT
cord-010027-r0tl01kq	100	14	integrated	integrate	VBN
cord-010027-r0tl01kq	100	15	approach	approach	NN
cord-010027-r0tl01kq	100	16	,	,	,
cord-010027-r0tl01kq	100	17	and	and	CC
cord-010027-r0tl01kq	100	18	both	both	DT
cord-010027-r0tl01kq	100	19	specificity	specificity	NN
cord-010027-r0tl01kq	100	20	and	and	CC
cord-010027-r0tl01kq	100	21	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	100	22	of	of	IN
cord-010027-r0tl01kq	100	23	the	the	DT
cord-010027-r0tl01kq	100	24	various	various	JJ
cord-010027-r0tl01kq	100	25	factors	factor	NNS
cord-010027-r0tl01kq	100	26	should	should	MD
cord-010027-r0tl01kq	100	27	be	be	VB
cord-010027-r0tl01kq	100	28	taken	take	VBN
cord-010027-r0tl01kq	100	29	into	into	IN
cord-010027-r0tl01kq	100	30	account	account	NN
cord-010027-r0tl01kq	100	31	.	.	.
cord-010027-r0tl01kq	101	1	Radical	radical	JJ
cord-010027-r0tl01kq	101	2	surgery	surgery	NN
cord-010027-r0tl01kq	101	3	seems	seem	VBZ
cord-010027-r0tl01kq	101	4	overtreatment	overtreatment	JJ
cord-010027-r0tl01kq	101	5	for	for	IN
cord-010027-r0tl01kq	101	6	a	a	DT
cord-010027-r0tl01kq	101	7	large	large	JJ
cord-010027-r0tl01kq	101	8	number	number	NN
cord-010027-r0tl01kq	101	9	of	of	IN
cord-010027-r0tl01kq	101	10	polyp	polyp	NN
cord-010027-r0tl01kq	101	11	cancers	cancer	NNS
cord-010027-r0tl01kq	101	12	.	.	.
cord-010027-r0tl01kq	102	1	Leeds	Leeds	NNP
cord-010027-r0tl01kq	102	2	University	University	NNP
cord-010027-r0tl01kq	102	3	,	,	,
cord-010027-r0tl01kq	102	4	Leeds	Leeds	NNP
cord-010027-r0tl01kq	102	5	,	,	,
cord-010027-r0tl01kq	102	6	UK	UK	NNP
cord-010027-r0tl01kq	102	7	Minimum	Minimum	NNP
cord-010027-r0tl01kq	102	8	datasets	dataset	NNS
cord-010027-r0tl01kq	102	9	have	have	VBP
cord-010027-r0tl01kq	102	10	changed	change	VBN
cord-010027-r0tl01kq	102	11	cancer	cancer	NN
cord-010027-r0tl01kq	102	12	reporting	reporting	NN
cord-010027-r0tl01kq	102	13	.	.	.
cord-010027-r0tl01kq	103	1	This	this	DT
cord-010027-r0tl01kq	103	2	talk	talk	NN
cord-010027-r0tl01kq	103	3	will	will	MD
cord-010027-r0tl01kq	103	4	explain	explain	VB
cord-010027-r0tl01kq	103	5	the	the	DT
cord-010027-r0tl01kq	103	6	decision	decision	NN
cord-010027-r0tl01kq	103	7	making	make	VBG
cord-010027-r0tl01kq	103	8	processes	process	NNS
cord-010027-r0tl01kq	103	9	behind	behind	IN
cord-010027-r0tl01kq	103	10	the	the	DT
cord-010027-r0tl01kq	103	11	latest	late	JJS
cord-010027-r0tl01kq	103	12	datasets	dataset	NNS
cord-010027-r0tl01kq	103	13	both	both	DT
cord-010027-r0tl01kq	103	14	for	for	IN
cord-010027-r0tl01kq	103	15	cancer	cancer	NN
cord-010027-r0tl01kq	103	16	reporting	reporting	NN
cord-010027-r0tl01kq	103	17	and	and	CC
cord-010027-r0tl01kq	103	18	bowel	bowel	NN
cord-010027-r0tl01kq	103	19	cancer	cancer	NN
cord-010027-r0tl01kq	103	20	screening	screening	NN
cord-010027-r0tl01kq	103	21	.	.	.
cord-010027-r0tl01kq	104	1	It	-PRON-	PRP
cord-010027-r0tl01kq	104	2	will	will	MD
cord-010027-r0tl01kq	104	3	also	also	RB
cord-010027-r0tl01kq	104	4	look	look	VB
cord-010027-r0tl01kq	104	5	at	at	IN
cord-010027-r0tl01kq	104	6	where	where	WRB
cord-010027-r0tl01kq	104	7	we	-PRON-	PRP
cord-010027-r0tl01kq	104	8	may	may	MD
cord-010027-r0tl01kq	104	9	be	be	VB
cord-010027-r0tl01kq	104	10	going	go	VBG
cord-010027-r0tl01kq	104	11	in	in	IN
cord-010027-r0tl01kq	104	12	the	the	DT
cord-010027-r0tl01kq	104	13	future	future	NN
cord-010027-r0tl01kq	104	14	for	for	IN
cord-010027-r0tl01kq	104	15	staging	stage	VBG
cord-010027-r0tl01kq	104	16	and	and	CC
cord-010027-r0tl01kq	104	17	molecular	molecular	JJ
cord-010027-r0tl01kq	104	18	reporting	reporting	NN
cord-010027-r0tl01kq	104	19	.	.	.
cord-010027-r0tl01kq	105	1	The	the	DT
cord-010027-r0tl01kq	105	2	intestines	intestine	NNS
cord-010027-r0tl01kq	105	3	play	play	VBP
cord-010027-r0tl01kq	105	4	host	host	NN
cord-010027-r0tl01kq	105	5	to	to	IN
cord-010027-r0tl01kq	105	6	a	a	DT
cord-010027-r0tl01kq	105	7	broad	broad	JJ
cord-010027-r0tl01kq	105	8	spectrum	spectrum	NN
cord-010027-r0tl01kq	105	9	of	of	IN
cord-010027-r0tl01kq	105	10	infective	infective	JJ
cord-010027-r0tl01kq	105	11	organisms	organism	NNS
cord-010027-r0tl01kq	105	12	ranging	range	VBG
cord-010027-r0tl01kq	105	13	from	from	IN
cord-010027-r0tl01kq	105	14	viruses	virus	NNS
cord-010027-r0tl01kq	105	15	,	,	,
cord-010027-r0tl01kq	105	16	through	through	IN
cord-010027-r0tl01kq	105	17	bacteria	bacteria	NNS
cord-010027-r0tl01kq	105	18	,	,	,
cord-010027-r0tl01kq	105	19	fungi	fungus	NNS
cord-010027-r0tl01kq	105	20	and	and	CC
cord-010027-r0tl01kq	105	21	unicellular	unicellular	JJ
cord-010027-r0tl01kq	105	22	parasites	parasite	NNS
cord-010027-r0tl01kq	105	23	to	to	IN
cord-010027-r0tl01kq	105	24	worms	worm	NNS
cord-010027-r0tl01kq	105	25	.	.	.
cord-010027-r0tl01kq	106	1	The	the	DT
cord-010027-r0tl01kq	106	2	spectrum	spectrum	NN
cord-010027-r0tl01kq	106	3	of	of	IN
cord-010027-r0tl01kq	106	4	infections	infection	NNS
cord-010027-r0tl01kq	106	5	seen	see	VBN
cord-010027-r0tl01kq	106	6	varies	vary	VBZ
cord-010027-r0tl01kq	106	7	with	with	IN
cord-010027-r0tl01kq	106	8	geographical	geographical	JJ
cord-010027-r0tl01kq	106	9	location	location	NN
cord-010027-r0tl01kq	106	10	,	,	,
cord-010027-r0tl01kq	106	11	due	due	IN
cord-010027-r0tl01kq	106	12	to	to	IN
cord-010027-r0tl01kq	106	13	socioeconomic	socioeconomic	JJ
cord-010027-r0tl01kq	106	14	factors	factor	NNS
cord-010027-r0tl01kq	106	15	and	and	CC
cord-010027-r0tl01kq	106	16	due	due	IN
cord-010027-r0tl01kq	106	17	to	to	IN
cord-010027-r0tl01kq	106	18	changes	change	NNS
cord-010027-r0tl01kq	106	19	in	in	IN
cord-010027-r0tl01kq	106	20	human	human	JJ
cord-010027-r0tl01kq	106	21	behaviour	behaviour	NN
cord-010027-r0tl01kq	106	22	.	.	.
cord-010027-r0tl01kq	107	1	Immunocompromisation	Immunocompromisation	NNP
cord-010027-r0tl01kq	107	2	due	due	IN
cord-010027-r0tl01kq	107	3	to	to	IN
cord-010027-r0tl01kq	107	4	infections	infection	NNS
cord-010027-r0tl01kq	107	5	(	(	-LRB-
cord-010027-r0tl01kq	107	6	in	in	IN
cord-010027-r0tl01kq	107	7	particular	particular	JJ
cord-010027-r0tl01kq	107	8	HIV	HIV	NNP
cord-010027-r0tl01kq	107	9	)	)	-RRB-
cord-010027-r0tl01kq	107	10	,	,	,
cord-010027-r0tl01kq	107	11	malignancy	malignancy	NN
cord-010027-r0tl01kq	107	12	(	(	-LRB-
cord-010027-r0tl01kq	107	13	especially	especially	RB
cord-010027-r0tl01kq	107	14	haematological	haematological	JJ
cord-010027-r0tl01kq	107	15	tumours	tumour	NNS
cord-010027-r0tl01kq	107	16	)	)	-RRB-
cord-010027-r0tl01kq	107	17	and	and	CC
cord-010027-r0tl01kq	107	18	the	the	DT
cord-010027-r0tl01kq	107	19	use	use	NN
cord-010027-r0tl01kq	107	20	of	of	IN
cord-010027-r0tl01kq	107	21	immunosuppressive	immunosuppressive	JJ
cord-010027-r0tl01kq	107	22	drugs	drug	NNS
cord-010027-r0tl01kq	107	23	also	also	RB
cord-010027-r0tl01kq	107	24	has	have	VBZ
cord-010027-r0tl01kq	107	25	an	an	DT
cord-010027-r0tl01kq	107	26	important	important	JJ
cord-010027-r0tl01kq	107	27	role	role	NN
cord-010027-r0tl01kq	107	28	in	in	IN
cord-010027-r0tl01kq	107	29	determining	determine	VBG
cord-010027-r0tl01kq	107	30	the	the	DT
cord-010027-r0tl01kq	107	31	infections	infection	NNS
cord-010027-r0tl01kq	107	32	commonly	commonly	RB
cord-010027-r0tl01kq	107	33	seen	see	VBN
cord-010027-r0tl01kq	107	34	in	in	IN
cord-010027-r0tl01kq	107	35	the	the	DT
cord-010027-r0tl01kq	107	36	GI	GI	NNP
cord-010027-r0tl01kq	107	37	tract	tract	NN
cord-010027-r0tl01kq	107	38	.	.	.
cord-010027-r0tl01kq	108	1	The	the	DT
cord-010027-r0tl01kq	108	2	typical	typical	JJ
cord-010027-r0tl01kq	108	3	pathological	pathological	JJ
cord-010027-r0tl01kq	108	4	features	feature	NNS
cord-010027-r0tl01kq	108	5	of	of	IN
cord-010027-r0tl01kq	108	6	intestinal	intestinal	JJ
cord-010027-r0tl01kq	108	7	infections	infection	NNS
cord-010027-r0tl01kq	108	8	will	will	MD
cord-010027-r0tl01kq	108	9	be	be	VB
cord-010027-r0tl01kq	108	10	discussed	discuss	VBN
cord-010027-r0tl01kq	108	11	together	together	RB
cord-010027-r0tl01kq	108	12	with	with	IN
cord-010027-r0tl01kq	108	13	suggestions	suggestion	NNS
cord-010027-r0tl01kq	108	14	on	on	IN
cord-010027-r0tl01kq	108	15	how	how	WRB
cord-010027-r0tl01kq	108	16	to	to	TO
cord-010027-r0tl01kq	108	17	optimise	optimise	VB
cord-010027-r0tl01kq	108	18	the	the	DT
cord-010027-r0tl01kq	108	19	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	108	20	of	of	IN
cord-010027-r0tl01kq	108	21	such	such	JJ
cord-010027-r0tl01kq	108	22	pathologies	pathology	NNS
cord-010027-r0tl01kq	108	23	.	.	.
cord-010027-r0tl01kq	109	1	Erasme	Erasme	NNP
cord-010027-r0tl01kq	109	2	University	University	NNP
cord-010027-r0tl01kq	109	3	Hospital	Hospital	NNP
cord-010027-r0tl01kq	109	4	,	,	,
cord-010027-r0tl01kq	109	5	Brussels	Brussels	NNP
cord-010027-r0tl01kq	109	6	,	,	,
cord-010027-r0tl01kq	109	7	Belgium	Belgium	NNP
cord-010027-r0tl01kq	109	8	Pathologists	Pathologists	NNPS
cord-010027-r0tl01kq	109	9	are	be	VBP
cord-010027-r0tl01kq	109	10	confronted	confront	VBN
cord-010027-r0tl01kq	109	11	with	with	IN
cord-010027-r0tl01kq	109	12	different	different	JJ
cord-010027-r0tl01kq	109	13	types	type	NNS
cord-010027-r0tl01kq	109	14	of	of	IN
cord-010027-r0tl01kq	109	15	colitis	colitis	NN
cord-010027-r0tl01kq	109	16	,	,	,
cord-010027-r0tl01kq	109	17	most	most	RBS
cord-010027-r0tl01kq	109	18	commonly	commonly	RB
cord-010027-r0tl01kq	109	19	infectious	infectious	JJ
cord-010027-r0tl01kq	109	20	colitis	colitis	NN
cord-010027-r0tl01kq	109	21	and	and	CC
cord-010027-r0tl01kq	109	22	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	109	23	bowel	bowel	NN
cord-010027-r0tl01kq	109	24	disease	disease	NN
cord-010027-r0tl01kq	109	25	(	(	-LRB-
cord-010027-r0tl01kq	109	26	IBD	IBD	NNP
cord-010027-r0tl01kq	109	27	)	)	-RRB-
cord-010027-r0tl01kq	109	28	followed	follow	VBN
cord-010027-r0tl01kq	109	29	by	by	IN
cord-010027-r0tl01kq	109	30	microscopic	microscopic	JJ
cord-010027-r0tl01kq	109	31	colitis	colitis	NN
cord-010027-r0tl01kq	109	32	and	and	CC
cord-010027-r0tl01kq	109	33	ischaemic	ischaemic	JJ
cord-010027-r0tl01kq	109	34	colitis	colitis	NN
cord-010027-r0tl01kq	109	35	.	.	.
cord-010027-r0tl01kq	110	1	Several	several	JJ
cord-010027-r0tl01kq	110	2	other	other	JJ
cord-010027-r0tl01kq	110	3	forms	form	NNS
cord-010027-r0tl01kq	110	4	of	of	IN
cord-010027-r0tl01kq	110	5	colitis	colitis	NN
cord-010027-r0tl01kq	110	6	,	,	,
cord-010027-r0tl01kq	110	7	however	however	RB
cord-010027-r0tl01kq	110	8	,	,	,
cord-010027-r0tl01kq	110	9	exist	exist	VBP
cord-010027-r0tl01kq	110	10	and	and	CC
cord-010027-r0tl01kq	110	11	might	may	MD
cord-010027-r0tl01kq	110	12	be	be	VB
cord-010027-r0tl01kq	110	13	underrecognised	underrecognise	VBN
cord-010027-r0tl01kq	110	14	;	;	:
cord-010027-r0tl01kq	110	15	these	these	DT
cord-010027-r0tl01kq	110	16	diseases	disease	NNS
cord-010027-r0tl01kq	110	17	include	include	VBP
cord-010027-r0tl01kq	110	18	segmental	segmental	JJ
cord-010027-r0tl01kq	110	19	colitis	colitis	NN
cord-010027-r0tl01kq	110	20	associated	associate	VBN
cord-010027-r0tl01kq	110	21	with	with	IN
cord-010027-r0tl01kq	110	22	diverticulosis	diverticulosis	NN
cord-010027-r0tl01kq	110	23	,	,	,
cord-010027-r0tl01kq	110	24	diversion	diversion	NN
cord-010027-r0tl01kq	110	25	colitis	colitis	NN
cord-010027-r0tl01kq	110	26	,	,	,
cord-010027-r0tl01kq	110	27	eosinophilic	eosinophilic	JJ
cord-010027-r0tl01kq	110	28	colitis	colitis	NN
cord-010027-r0tl01kq	110	29	and	and	CC
cord-010027-r0tl01kq	110	30	Behcet	Behcet	NNP
cord-010027-r0tl01kq	110	31	's	's	POS
cord-010027-r0tl01kq	110	32	colitis	colitis	NN
cord-010027-r0tl01kq	110	33	.	.	.
cord-010027-r0tl01kq	111	1	Clinical	clinical	JJ
cord-010027-r0tl01kq	111	2	presentations	presentation	NNS
cord-010027-r0tl01kq	111	3	of	of	IN
cord-010027-r0tl01kq	111	4	these	these	DT
cord-010027-r0tl01kq	111	5	rare	rare	JJ
cord-010027-r0tl01kq	111	6	types	type	NNS
cord-010027-r0tl01kq	111	7	of	of	IN
cord-010027-r0tl01kq	111	8	colitis	colitis	NN
cord-010027-r0tl01kq	111	9	vary	vary	VBP
cord-010027-r0tl01kq	111	10	,	,	,
cord-010027-r0tl01kq	111	11	and	and	CC
cord-010027-r0tl01kq	111	12	laboratory	laboratory	NN
cord-010027-r0tl01kq	111	13	data	datum	NNS
cord-010027-r0tl01kq	111	14	are	be	VBP
cord-010027-r0tl01kq	111	15	often	often	RB
cord-010027-r0tl01kq	111	16	non	non	JJ
cord-010027-r0tl01kq	111	17	-	-	JJ
cord-010027-r0tl01kq	111	18	specific	specific	JJ
cord-010027-r0tl01kq	111	19	;	;	:
cord-010027-r0tl01kq	111	20	mucosal	mucosal	JJ
cord-010027-r0tl01kq	111	21	biopsy	biopsy	NN
cord-010027-r0tl01kq	111	22	is	be	VBZ
cord-010027-r0tl01kq	111	23	essential	essential	JJ
cord-010027-r0tl01kq	111	24	in	in	IN
cord-010027-r0tl01kq	111	25	establishing	establish	VBG
cord-010027-r0tl01kq	111	26	the	the	DT
cord-010027-r0tl01kq	111	27	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	111	28	.	.	.
cord-010027-r0tl01kq	112	1	Segmental	Segmental	NNP
cord-010027-r0tl01kq	112	2	colitis	colitis	NN
cord-010027-r0tl01kq	112	3	associated	associate	VBN
cord-010027-r0tl01kq	112	4	with	with	IN
cord-010027-r0tl01kq	112	5	diverticulosis	diverticulosis	NN
cord-010027-r0tl01kq	112	6	(	(	-LRB-
cord-010027-r0tl01kq	112	7	SCAD	SCAD	NNP
cord-010027-r0tl01kq	112	8	)	)	-RRB-
cord-010027-r0tl01kq	112	9	is	be	VBZ
cord-010027-r0tl01kq	112	10	mainly	mainly	RB
cord-010027-r0tl01kq	112	11	characterised	characterise	VBN
cord-010027-r0tl01kq	112	12	by	by	IN
cord-010027-r0tl01kq	112	13	the	the	DT
cord-010027-r0tl01kq	112	14	involvement	involvement	NN
cord-010027-r0tl01kq	112	15	of	of	IN
cord-010027-r0tl01kq	112	16	the	the	DT
cord-010027-r0tl01kq	112	17	sigmoid	sigmoid	JJ
cord-010027-r0tl01kq	112	18	colon	colon	NN
cord-010027-r0tl01kq	112	19	with	with	IN
cord-010027-r0tl01kq	112	20	sparing	sparing	NN
cord-010027-r0tl01kq	112	21	of	of	IN
cord-010027-r0tl01kq	112	22	the	the	DT
cord-010027-r0tl01kq	112	23	rectum	rectum	NN
cord-010027-r0tl01kq	112	24	and	and	CC
cord-010027-r0tl01kq	112	25	proximal	proximal	JJ
cord-010027-r0tl01kq	112	26	colon	colon	NN
cord-010027-r0tl01kq	112	27	.	.	.
cord-010027-r0tl01kq	113	1	SCAD	SCAD	NNP
cord-010027-r0tl01kq	113	2	often	often	RB
cord-010027-r0tl01kq	113	3	mimics	mimic	VBZ
cord-010027-r0tl01kq	113	4	IBD	IBD	NNP
cord-010027-r0tl01kq	113	5	at	at	IN
cord-010027-r0tl01kq	113	6	endoscopic	endoscopic	NNS
cord-010027-r0tl01kq	113	7	and	and	CC
cord-010027-r0tl01kq	113	8	histological	histological	JJ
cord-010027-r0tl01kq	113	9	examination	examination	NN
cord-010027-r0tl01kq	113	10	;	;	:
cord-010027-r0tl01kq	113	11	since	since	IN
cord-010027-r0tl01kq	113	12	SCAD	SCAD	NNP
cord-010027-r0tl01kq	113	13	has	have	VBZ
cord-010027-r0tl01kq	113	14	a	a	DT
cord-010027-r0tl01kq	113	15	self	self	NN
cord-010027-r0tl01kq	113	16	-	-	HYPH
cord-010027-r0tl01kq	113	17	limited	limit	VBN
cord-010027-r0tl01kq	113	18	course	course	NN
cord-010027-r0tl01kq	113	19	that	that	WDT
cord-010027-r0tl01kq	113	20	resolves	resolve	VBZ
cord-010027-r0tl01kq	113	21	without	without	IN
cord-010027-r0tl01kq	113	22	further	further	JJ
cord-010027-r0tl01kq	113	23	recurrence	recurrence	NN
cord-010027-r0tl01kq	113	24	or	or	CC
cord-010027-r0tl01kq	113	25	need	need	NN
cord-010027-r0tl01kq	113	26	for	for	IN
cord-010027-r0tl01kq	113	27	treatment	treatment	NN
cord-010027-r0tl01kq	113	28	,	,	,
cord-010027-r0tl01kq	113	29	the	the	DT
cord-010027-r0tl01kq	113	30	implications	implication	NNS
cord-010027-r0tl01kq	113	31	of	of	IN
cord-010027-r0tl01kq	113	32	an	an	DT
cord-010027-r0tl01kq	113	33	inaccurate	inaccurate	JJ
cord-010027-r0tl01kq	113	34	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	113	35	are	be	VBP
cord-010027-r0tl01kq	113	36	obvious	obvious	JJ
cord-010027-r0tl01kq	113	37	.	.	.
cord-010027-r0tl01kq	114	1	Diversion	diversion	NN
cord-010027-r0tl01kq	114	2	colitis	colitis	NN
cord-010027-r0tl01kq	114	3	is	be	VBZ
cord-010027-r0tl01kq	114	4	a	a	DT
cord-010027-r0tl01kq	114	5	non	non	JJ
cord-010027-r0tl01kq	114	6	-	-	JJ
cord-010027-r0tl01kq	114	7	specific	specific	JJ
cord-010027-r0tl01kq	114	8	colonic	colonic	JJ
cord-010027-r0tl01kq	114	9	inflammation	inflammation	NN
cord-010027-r0tl01kq	114	10	following	follow	VBG
cord-010027-r0tl01kq	114	11	surgical	surgical	JJ
cord-010027-r0tl01kq	114	12	diversion	diversion	NN
cord-010027-r0tl01kq	114	13	of	of	IN
cord-010027-r0tl01kq	114	14	the	the	DT
cord-010027-r0tl01kq	114	15	faecal	faecal	JJ
cord-010027-r0tl01kq	114	16	stream	stream	NN
cord-010027-r0tl01kq	114	17	.	.	.
cord-010027-r0tl01kq	115	1	Is	be	VBZ
cord-010027-r0tl01kq	115	2	is	be	VBZ
cord-010027-r0tl01kq	115	3	characterised	characterise	VBN
cord-010027-r0tl01kq	115	4	by	by	IN
cord-010027-r0tl01kq	115	5	a	a	DT
cord-010027-r0tl01kq	115	6	chronic	chronic	JJ
cord-010027-r0tl01kq	115	7	lymphoplasmacytic	lymphoplasmacytic	JJ
cord-010027-r0tl01kq	115	8	infiltrate	infiltrate	NN
cord-010027-r0tl01kq	115	9	,	,	,
cord-010027-r0tl01kq	115	10	and	and	CC
cord-010027-r0tl01kq	115	11	the	the	DT
cord-010027-r0tl01kq	115	12	existence	existence	NN
cord-010027-r0tl01kq	115	13	of	of	IN
cord-010027-r0tl01kq	115	14	lymphoid	lymphoid	JJ
cord-010027-r0tl01kq	115	15	follicular	follicular	JJ
cord-010027-r0tl01kq	115	16	hyperplasia	hyperplasia	NN
cord-010027-r0tl01kq	115	17	is	be	VBZ
cord-010027-r0tl01kq	115	18	considered	consider	VBN
cord-010027-r0tl01kq	115	19	to	to	TO
cord-010027-r0tl01kq	115	20	be	be	VB
cord-010027-r0tl01kq	115	21	a	a	DT
cord-010027-r0tl01kq	115	22	hallmark	hallmark	JJ
cord-010027-r0tl01kq	115	23	feature	feature	NN
cord-010027-r0tl01kq	115	24	.	.	.
cord-010027-r0tl01kq	116	1	The	the	DT
cord-010027-r0tl01kq	116	2	development	development	NN
cord-010027-r0tl01kq	116	3	of	of	IN
cord-010027-r0tl01kq	116	4	diversion	diversion	NN
cord-010027-r0tl01kq	116	5	colitis	colitis	NN
cord-010027-r0tl01kq	116	6	is	be	VBZ
cord-010027-r0tl01kq	116	7	attributed	attribute	VBN
cord-010027-r0tl01kq	116	8	to	to	IN
cord-010027-r0tl01kq	116	9	a	a	DT
cord-010027-r0tl01kq	116	10	lack	lack	NN
cord-010027-r0tl01kq	116	11	of	of	IN
cord-010027-r0tl01kq	116	12	short	short	JJ
cord-010027-r0tl01kq	116	13	chain	chain	NN
cord-010027-r0tl01kq	116	14	fatty	fatty	JJ
cord-010027-r0tl01kq	116	15	acids	acid	NNS
cord-010027-r0tl01kq	116	16	.	.	.
cord-010027-r0tl01kq	117	1	Eosinophilic	eosinophilic	JJ
cord-010027-r0tl01kq	117	2	colitis	colitis	NN
cord-010027-r0tl01kq	117	3	is	be	VBZ
cord-010027-r0tl01kq	117	4	etiologically	etiologically	RB
cord-010027-r0tl01kq	117	5	obscure	obscure	JJ
cord-010027-r0tl01kq	117	6	and	and	CC
cord-010027-r0tl01kq	117	7	can	can	MD
cord-010027-r0tl01kq	117	8	be	be	VB
cord-010027-r0tl01kq	117	9	associated	associate	VBN
cord-010027-r0tl01kq	117	10	with	with	IN
cord-010027-r0tl01kq	117	11	involvement	involvement	NN
cord-010027-r0tl01kq	117	12	of	of	IN
cord-010027-r0tl01kq	117	13	other	other	JJ
cord-010027-r0tl01kq	117	14	sections	section	NNS
cord-010027-r0tl01kq	117	15	of	of	IN
cord-010027-r0tl01kq	117	16	the	the	DT
cord-010027-r0tl01kq	117	17	gastrointestinal	gastrointestinal	JJ
cord-010027-r0tl01kq	117	18	tract	tract	NN
cord-010027-r0tl01kq	117	19	.	.	.
cord-010027-r0tl01kq	118	1	An	an	DT
cord-010027-r0tl01kq	118	2	infiltrate	infiltrate	NN
cord-010027-r0tl01kq	118	3	of	of	IN
cord-010027-r0tl01kq	118	4	eosinophilic	eosinophilic	JJ
cord-010027-r0tl01kq	118	5	granulocytes	granulocyte	NNS
cord-010027-r0tl01kq	118	6	is	be	VBZ
cord-010027-r0tl01kq	118	7	found	find	VBN
cord-010027-r0tl01kq	118	8	to	to	IN
cord-010027-r0tl01kq	118	9	varying	vary	VBG
cord-010027-r0tl01kq	118	10	degrees	degree	NNS
cord-010027-r0tl01kq	118	11	in	in	IN
cord-010027-r0tl01kq	118	12	all	all	DT
cord-010027-r0tl01kq	118	13	wall	wall	NN
cord-010027-r0tl01kq	118	14	layers	layer	NNS
cord-010027-r0tl01kq	118	15	.	.	.
cord-010027-r0tl01kq	119	1	A	a	DT
cord-010027-r0tl01kq	119	2	history	history	NN
cord-010027-r0tl01kq	119	3	of	of	IN
cord-010027-r0tl01kq	119	4	food	food	NN
cord-010027-r0tl01kq	119	5	intolerance	intolerance	NN
cord-010027-r0tl01kq	119	6	or	or	CC
cord-010027-r0tl01kq	119	7	allergy	allergy	NN
cord-010027-r0tl01kq	119	8	is	be	VBZ
cord-010027-r0tl01kq	119	9	present	present	JJ
cord-010027-r0tl01kq	119	10	in	in	IN
cord-010027-r0tl01kq	119	11	most	most	JJS
cord-010027-r0tl01kq	119	12	of	of	IN
cord-010027-r0tl01kq	119	13	the	the	DT
cord-010027-r0tl01kq	119	14	patients	patient	NNS
cord-010027-r0tl01kq	119	15	,	,	,
cord-010027-r0tl01kq	119	16	and	and	CC
cord-010027-r0tl01kq	119	17	peripheral	peripheral	JJ
cord-010027-r0tl01kq	119	18	eosinophilia	eosinophilia	NN
cord-010027-r0tl01kq	119	19	is	be	VBZ
cord-010027-r0tl01kq	119	20	present	present	JJ
cord-010027-r0tl01kq	119	21	in	in	IN
cord-010027-r0tl01kq	119	22	80	80	CD
cord-010027-r0tl01kq	119	23	%	%	NN
cord-010027-r0tl01kq	119	24	of	of	IN
cord-010027-r0tl01kq	119	25	cases	case	NNS
cord-010027-r0tl01kq	119	26	.	.	.
cord-010027-r0tl01kq	120	1	Gastrointestinal	gastrointestinal	JJ
cord-010027-r0tl01kq	120	2	involvement	involvement	NN
cord-010027-r0tl01kq	120	3	has	have	VBZ
cord-010027-r0tl01kq	120	4	been	be	VBN
cord-010027-r0tl01kq	120	5	reported	report	VBN
cord-010027-r0tl01kq	120	6	in	in	IN
cord-010027-r0tl01kq	120	7	up	up	IN
cord-010027-r0tl01kq	120	8	to	to	TO
cord-010027-r0tl01kq	120	9	25	25	CD
cord-010027-r0tl01kq	120	10	%	%	NN
cord-010027-r0tl01kq	120	11	of	of	IN
cord-010027-r0tl01kq	120	12	patients	patient	NNS
cord-010027-r0tl01kq	120	13	with	with	IN
cord-010027-r0tl01kq	120	14	Behcet	Behcet	NNP
cord-010027-r0tl01kq	120	15	's	's	POS
cord-010027-r0tl01kq	120	16	disease	disease	NN
cord-010027-r0tl01kq	120	17	.	.	.
cord-010027-r0tl01kq	121	1	In	in	IN
cord-010027-r0tl01kq	121	2	cases	case	NNS
cord-010027-r0tl01kq	121	3	with	with	IN
cord-010027-r0tl01kq	121	4	ileocolonic	ileocolonic	JJ
cord-010027-r0tl01kq	121	5	involvement	involvement	NN
cord-010027-r0tl01kq	121	6	,	,	,
cord-010027-r0tl01kq	121	7	it	-PRON-	PRP
cord-010027-r0tl01kq	121	8	is	be	VBZ
cord-010027-r0tl01kq	121	9	often	often	RB
cord-010027-r0tl01kq	121	10	difficult	difficult	JJ
cord-010027-r0tl01kq	121	11	to	to	TO
cord-010027-r0tl01kq	121	12	distinguish	distinguish	VB
cord-010027-r0tl01kq	121	13	Behcet	Behcet	NNP
cord-010027-r0tl01kq	121	14	's	's	POS
cord-010027-r0tl01kq	121	15	disease	disease	NN
cord-010027-r0tl01kq	121	16	from	from	IN
cord-010027-r0tl01kq	121	17	other	other	JJ
cord-010027-r0tl01kq	121	18	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	121	19	bowel	bowel	NN
cord-010027-r0tl01kq	121	20	diseases	disease	NNS
cord-010027-r0tl01kq	121	21	.	.	.
cord-010027-r0tl01kq	122	1	The	the	DT
cord-010027-r0tl01kq	122	2	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	122	3	,	,	,
cord-010027-r0tl01kq	122	4	therefore	therefore	RB
cord-010027-r0tl01kq	122	5	,	,	,
cord-010027-r0tl01kq	122	6	often	often	RB
cord-010027-r0tl01kq	122	7	depends	depend	VBZ
cord-010027-r0tl01kq	122	8	on	on	IN
cord-010027-r0tl01kq	122	9	clinical	clinical	JJ
cord-010027-r0tl01kq	122	10	manifestations	manifestation	NNS
cord-010027-r0tl01kq	122	11	and	and	CC
cord-010027-r0tl01kq	122	12	intestinal	intestinal	JJ
cord-010027-r0tl01kq	122	13	ulcerative	ulcerative	JJ
cord-010027-r0tl01kq	122	14	lesions	lesion	NNS
cord-010027-r0tl01kq	122	15	.	.	.
cord-010027-r0tl01kq	123	1	S·8	S·8	NNP
cord-010027-r0tl01kq	123	2			.
cord-010027-r0tl01kq	124	1	How	how	WRB
cord-010027-r0tl01kq	124	2	to	to	TO
cord-010027-r0tl01kq	124	3	Write	write	VB
cord-010027-r0tl01kq	124	4	a	a	DT
cord-010027-r0tl01kq	124	5	Paper	paper	NN
cord-010027-r0tl01kq	124	6	and	and	CC
cord-010027-r0tl01kq	124	7	Get	get	VB
cord-010027-r0tl01kq	124	8	it	-PRON-	PRP
cord-010027-r0tl01kq	124	9	Published	published	JJ
cord-010027-r0tl01kq	124	10	P	p	NN
cord-010027-r0tl01kq	124	11	CS	CS	NNP
cord-010027-r0tl01kq	124	12	Herrington	Herrington	NNP
cord-010027-r0tl01kq	124	13	1	1	CD
cord-010027-r0tl01kq	124	14	;	;	:
cord-010027-r0tl01kq	124	15	P	p	NN
cord-010027-r0tl01kq	124	16	DM	dm	NN
cord-010027-r0tl01kq	124	17	Berney	Berney	NNP
cord-010027-r0tl01kq	124	18	2	2	CD
cord-010027-r0tl01kq	124	19	1	1	CD
cord-010027-r0tl01kq	124	20	University	University	NNP
cord-010027-r0tl01kq	124	21	of	of	IN
cord-010027-r0tl01kq	124	22	Edinburgh	Edinburgh	NNP
cord-010027-r0tl01kq	124	23	,	,	,
cord-010027-r0tl01kq	124	24	Edinburgh	Edinburgh	NNP
cord-010027-r0tl01kq	124	25	,	,	,
cord-010027-r0tl01kq	124	26	UK	UK	NNP
cord-010027-r0tl01kq	124	27	;	;	:
cord-010027-r0tl01kq	124	28	2	2	CD
cord-010027-r0tl01kq	124	29	Barts	Barts	NNPS
cord-010027-r0tl01kq	124	30	Health	Health	NNP
cord-010027-r0tl01kq	124	31	NHS	NHS	NNP
cord-010027-r0tl01kq	124	32	Trust	Trust	NNP
cord-010027-r0tl01kq	124	33	,	,	,
cord-010027-r0tl01kq	124	34	London	London	NNP
cord-010027-r0tl01kq	124	35	,	,	,
cord-010027-r0tl01kq	124	36	UK	UK	NNP
cord-010027-r0tl01kq	124	37	Scientific	scientific	JJ
cord-010027-r0tl01kq	124	38	papers	paper	NNS
cord-010027-r0tl01kq	124	39	have	have	VBP
cord-010027-r0tl01kq	124	40	a	a	DT
cord-010027-r0tl01kq	124	41	predetermined	predetermine	VBN
cord-010027-r0tl01kq	124	42	structure	structure	NN
cord-010027-r0tl01kq	124	43	,	,	,
cord-010027-r0tl01kq	124	44	and	and	CC
cord-010027-r0tl01kq	124	45	writing	write	VBG
cord-010027-r0tl01kq	124	46	in	in	IN
cord-010027-r0tl01kq	124	47	this	this	DT
cord-010027-r0tl01kq	124	48	way	way	NN
cord-010027-r0tl01kq	124	49	requires	require	VBZ
cord-010027-r0tl01kq	124	50	practice	practice	NN
cord-010027-r0tl01kq	124	51	.	.	.
cord-010027-r0tl01kq	125	1	Most	Most	JJS
cord-010027-r0tl01kq	125	2	Journals	journal	NNS
cord-010027-r0tl01kq	125	3	accept	accept	VBP
cord-010027-r0tl01kq	125	4	only	only	RB
cord-010027-r0tl01kq	125	5	a	a	DT
cord-010027-r0tl01kq	125	6	small	small	JJ
cord-010027-r0tl01kq	125	7	fraction	fraction	NN
cord-010027-r0tl01kq	125	8	of	of	IN
cord-010027-r0tl01kq	125	9	submitted	submit	VBN
cord-010027-r0tl01kq	125	10	papers	paper	NNS
cord-010027-r0tl01kq	125	11	and	and	CC
cord-010027-r0tl01kq	125	12	it	-PRON-	PRP
cord-010027-r0tl01kq	125	13	is	be	VBZ
cord-010027-r0tl01kq	125	14	important	important	JJ
cord-010027-r0tl01kq	125	15	that	that	IN
cord-010027-r0tl01kq	125	16	any	any	DT
cord-010027-r0tl01kq	125	17	paper	paper	NN
cord-010027-r0tl01kq	125	18	has	have	VBZ
cord-010027-r0tl01kq	125	19	something	something	NN
cord-010027-r0tl01kq	125	20	specific	specific	JJ
cord-010027-r0tl01kq	125	21	to	to	TO
cord-010027-r0tl01kq	125	22	say	say	VB
cord-010027-r0tl01kq	125	23	;	;	:
cord-010027-r0tl01kq	125	24	and	and	CC
cord-010027-r0tl01kq	125	25	says	say	VBZ
cord-010027-r0tl01kq	125	26	it	-PRON-	PRP
cord-010027-r0tl01kq	125	27	in	in	IN
cord-010027-r0tl01kq	125	28	a	a	DT
cord-010027-r0tl01kq	125	29	clear	clear	JJ
cord-010027-r0tl01kq	125	30	and	and	CC
cord-010027-r0tl01kq	125	31	concise	concise	JJ
cord-010027-r0tl01kq	125	32	way	way	NN
cord-010027-r0tl01kq	125	33	that	that	WDT
cord-010027-r0tl01kq	125	34	can	can	MD
cord-010027-r0tl01kq	125	35	be	be	VB
cord-010027-r0tl01kq	125	36	understood	understand	VBN
cord-010027-r0tl01kq	125	37	by	by	IN
cord-010027-r0tl01kq	125	38	editors	editor	NNS
cord-010027-r0tl01kq	125	39	,	,	,
cord-010027-r0tl01kq	125	40	reviewers	reviewer	NNS
cord-010027-r0tl01kq	125	41	and	and	CC
cord-010027-r0tl01kq	125	42	readers	reader	NNS
cord-010027-r0tl01kq	125	43	,	,	,
cord-010027-r0tl01kq	125	44	all	all	DT
cord-010027-r0tl01kq	125	45	of	of	IN
cord-010027-r0tl01kq	125	46	whom	whom	WP
cord-010027-r0tl01kq	125	47	play	play	VBP
cord-010027-r0tl01kq	125	48	a	a	DT
cord-010027-r0tl01kq	125	49	role	role	NN
cord-010027-r0tl01kq	125	50	in	in	IN
cord-010027-r0tl01kq	125	51	assessment	assessment	NN
cord-010027-r0tl01kq	125	52	of	of	IN
cord-010027-r0tl01kq	125	53	its	-PRON-	PRP$
cord-010027-r0tl01kq	125	54	contribution	contribution	NN
cord-010027-r0tl01kq	125	55	.	.	.
cord-010027-r0tl01kq	126	1	Editors	editor	NNS
cord-010027-r0tl01kq	126	2	look	look	VBP
cord-010027-r0tl01kq	126	3	for	for	IN
cord-010027-r0tl01kq	126	4	novelty	novelty	NN
cord-010027-r0tl01kq	126	5	and	and	CC
cord-010027-r0tl01kq	126	6	significance	significance	NN
cord-010027-r0tl01kq	126	7	in	in	IN
cord-010027-r0tl01kq	126	8	the	the	DT
cord-010027-r0tl01kq	126	9	context	context	NN
cord-010027-r0tl01kq	126	10	of	of	IN
cord-010027-r0tl01kq	126	11	the	the	DT
cord-010027-r0tl01kq	126	12	aims	aim	NNS
cord-010027-r0tl01kq	126	13	and	and	CC
cord-010027-r0tl01kq	126	14	scope	scope	NN
cord-010027-r0tl01kq	126	15	of	of	IN
cord-010027-r0tl01kq	126	16	their	-PRON-	PRP$
cord-010027-r0tl01kq	126	17	Journal	Journal	NNP
cord-010027-r0tl01kq	126	18	;	;	,
cord-010027-r0tl01kq	126	19	and	and	CC
cord-010027-r0tl01kq	126	20	scientific	scientific	JJ
cord-010027-r0tl01kq	126	21	rigour	rigour	NN
cord-010027-r0tl01kq	126	22	,	,	,
cord-010027-r0tl01kq	126	23	which	which	WDT
cord-010027-r0tl01kq	126	24	expert	expert	NN
cord-010027-r0tl01kq	126	25	reviewers	reviewer	NNS
cord-010027-r0tl01kq	126	26	help	help	VBP
cord-010027-r0tl01kq	126	27	them	-PRON-	PRP
cord-010027-r0tl01kq	126	28	to	to	TO
cord-010027-r0tl01kq	126	29	assess	assess	VB
cord-010027-r0tl01kq	126	30	.	.	.
cord-010027-r0tl01kq	127	1	Writing	write	VBG
cord-010027-r0tl01kq	127	2	a	a	DT
cord-010027-r0tl01kq	127	3	paper	paper	NN
cord-010027-r0tl01kq	127	4	and	and	CC
cord-010027-r0tl01kq	127	5	having	have	VBG
cord-010027-r0tl01kq	127	6	it	-PRON-	PRP
cord-010027-r0tl01kq	127	7	assessed	assess	VBN
cord-010027-r0tl01kq	127	8	by	by	IN
cord-010027-r0tl01kq	127	9	a	a	DT
cord-010027-r0tl01kq	127	10	Journal	Journal	NNP
cord-010027-r0tl01kq	127	11	is	be	VBZ
cord-010027-r0tl01kq	127	12	an	an	DT
cord-010027-r0tl01kq	127	13	iterative	iterative	JJ
cord-010027-r0tl01kq	127	14	process	process	NN
cord-010027-r0tl01kq	127	15	.	.	.
cord-010027-r0tl01kq	128	1	During	during	IN
cord-010027-r0tl01kq	128	2	the	the	DT
cord-010027-r0tl01kq	128	3	writing	writing	NN
cord-010027-r0tl01kq	128	4	phase	phase	NN
cord-010027-r0tl01kq	128	5	,	,	,
cord-010027-r0tl01kq	128	6	the	the	DT
cord-010027-r0tl01kq	128	7	scientific	scientific	JJ
cord-010027-r0tl01kq	128	8	rigour	rigour	NN
cord-010027-r0tl01kq	128	9	of	of	IN
cord-010027-r0tl01kq	128	10	the	the	DT
cord-010027-r0tl01kq	128	11	argument	argument	NN
cord-010027-r0tl01kq	128	12	can	can	MD
cord-010027-r0tl01kq	128	13	be	be	VB
cord-010027-r0tl01kq	128	14	refined	refine	VBN
cord-010027-r0tl01kq	128	15	;	;	:
cord-010027-r0tl01kq	128	16	and	and	CC
cord-010027-r0tl01kq	128	17	following	follow	VBG
cord-010027-r0tl01kq	128	18	submission	submission	NN
cord-010027-r0tl01kq	128	19	and	and	CC
cord-010027-r0tl01kq	128	20	peer	peer	NN
cord-010027-r0tl01kq	128	21	review	review	NN
cord-010027-r0tl01kq	128	22	,	,	,
cord-010027-r0tl01kq	128	23	reviewers	reviewer	NNS
cord-010027-r0tl01kq	128	24	and	and	CC
cord-010027-r0tl01kq	128	25	editors	editor	NNS
cord-010027-r0tl01kq	128	26	often	often	RB
cord-010027-r0tl01kq	128	27	make	make	VBP
cord-010027-r0tl01kq	128	28	constructive	constructive	JJ
cord-010027-r0tl01kq	128	29	comments	comment	NNS
cord-010027-r0tl01kq	128	30	that	that	WDT
cord-010027-r0tl01kq	128	31	help	help	VBP
cord-010027-r0tl01kq	128	32	to	to	TO
cord-010027-r0tl01kq	128	33	improve	improve	VB
cord-010027-r0tl01kq	128	34	it	-PRON-	PRP
cord-010027-r0tl01kq	128	35	still	still	RB
cord-010027-r0tl01kq	128	36	further	further	RB
cord-010027-r0tl01kq	128	37	.	.	.
cord-010027-r0tl01kq	129	1	The	the	DT
cord-010027-r0tl01kq	129	2	peer	peer	NN
cord-010027-r0tl01kq	129	3	review	review	NN
cord-010027-r0tl01kq	129	4	process	process	NN
cord-010027-r0tl01kq	129	5	therefore	therefore	RB
cord-010027-r0tl01kq	129	6	acts	act	VBZ
cord-010027-r0tl01kq	129	7	not	not	RB
cord-010027-r0tl01kq	129	8	only	only	RB
cord-010027-r0tl01kq	129	9	as	as	IN
cord-010027-r0tl01kq	129	10	a	a	DT
cord-010027-r0tl01kq	129	11	quality	quality	NN
cord-010027-r0tl01kq	129	12	filter	filter	NN
cord-010027-r0tl01kq	129	13	but	but	CC
cord-010027-r0tl01kq	129	14	also	also	RB
cord-010027-r0tl01kq	129	15	as	as	IN
cord-010027-r0tl01kq	129	16	a	a	DT
cord-010027-r0tl01kq	129	17	mechanism	mechanism	NN
cord-010027-r0tl01kq	129	18	for	for	IN
cord-010027-r0tl01kq	129	19	quality	quality	NN
cord-010027-r0tl01kq	129	20	improvement	improvement	NN
cord-010027-r0tl01kq	129	21	.	.	.
cord-010027-r0tl01kq	130	1	Writing	writing	NN
cord-010027-r0tl01kq	130	2	papers	paper	NNS
cord-010027-r0tl01kq	130	3	and	and	CC
cord-010027-r0tl01kq	130	4	submitting	submit	VBG
cord-010027-r0tl01kq	130	5	them	-PRON-	PRP
cord-010027-r0tl01kq	130	6	for	for	IN
cord-010027-r0tl01kq	130	7	publication	publication	NN
cord-010027-r0tl01kq	130	8	is	be	VBZ
cord-010027-r0tl01kq	130	9	therefore	therefore	RB
cord-010027-r0tl01kq	130	10	generally	generally	RB
cord-010027-r0tl01kq	130	11	a	a	DT
cord-010027-r0tl01kq	130	12	positive	positive	JJ
cord-010027-r0tl01kq	130	13	experience	experience	NN
cord-010027-r0tl01kq	130	14	,	,	,
cord-010027-r0tl01kq	130	15	particularly	particularly	RB
cord-010027-r0tl01kq	130	16	if	if	IN
cord-010027-r0tl01kq	130	17	one	one	CD
cord-010027-r0tl01kq	130	18	remembers	remember	VBZ
cord-010027-r0tl01kq	130	19	that	that	IN
cord-010027-r0tl01kq	130	20	the	the	DT
cord-010027-r0tl01kq	130	21	process	process	NN
cord-010027-r0tl01kq	130	22	is	be	VBZ
cord-010027-r0tl01kq	130	23	iterative	iterative	JJ
cord-010027-r0tl01kq	130	24	and	and	CC
cord-010027-r0tl01kq	130	25	(	(	-LRB-
cord-010027-r0tl01kq	130	26	inevitably	inevitably	RB
cord-010027-r0tl01kq	130	27	)	)	-RRB-
cord-010027-r0tl01kq	130	28	not	not	RB
cord-010027-r0tl01kq	130	29	all	all	DT
cord-010027-r0tl01kq	130	30	papers	paper	NNS
cord-010027-r0tl01kq	130	31	will	will	MD
cord-010027-r0tl01kq	130	32	be	be	VB
cord-010027-r0tl01kq	130	33	accepted	accept	VBN
cord-010027-r0tl01kq	130	34	for	for	IN
cord-010027-r0tl01kq	130	35	publication	publication	NN
cord-010027-r0tl01kq	130	36	by	by	IN
cord-010027-r0tl01kq	130	37	the	the	DT
cord-010027-r0tl01kq	130	38	first	first	JJ
cord-010027-r0tl01kq	130	39	Journal	Journal	NNP
cord-010027-r0tl01kq	130	40	that	that	IN
cord-010027-r0tl01kq	130	41	they	-PRON-	PRP
cord-010027-r0tl01kq	130	42	are	be	VBP
cord-010027-r0tl01kq	130	43	sent	send	VBN
cord-010027-r0tl01kq	130	44	to	to	IN
cord-010027-r0tl01kq	130	45	.	.	.
cord-010027-r0tl01kq	131	1			NFP
cord-010027-r0tl01kq	131	2	Large	large	JJ
cord-010027-r0tl01kq	131	3	-	-	HYPH
cord-010027-r0tl01kq	131	4	Scale	scale	NN
cord-010027-r0tl01kq	131	5	Routine	Routine	NNP
cord-010027-r0tl01kq	131	6	Diagnostics	diagnostic	NNS
cord-010027-r0tl01kq	131	7	Using	use	VBG
cord-010027-r0tl01kq	131	8	Whole	Whole	NNP
cord-010027-r0tl01kq	131	9	-	-	HYPH
cord-010027-r0tl01kq	131	10	Slide	slide	NN
cord-010027-r0tl01kq	131	11	Imaging	Imaging	NNP
cord-010027-r0tl01kq	131	12	in	in	IN
cord-010027-r0tl01kq	131	13	Sweden	Sweden	NNP
cord-010027-r0tl01kq	132	1	-the	-the	NFP
cord-010027-r0tl01kq	133	1	Linköping	linköpe	VBG
cord-010027-r0tl01kq	133	2	Experience	experience	NN
cord-010027-r0tl01kq	134	1	P	p	NN
cord-010027-r0tl01kq	134	2	C	c	NN
cord-010027-r0tl01kq	134	3	Lundström	Lundström	NNP
cord-010027-r0tl01kq	134	4	CMIV	CMIV	NNP
cord-010027-r0tl01kq	134	5	,	,	,
cord-010027-r0tl01kq	134	6	Linköping	Linköping	NNP
cord-010027-r0tl01kq	134	7	University	University	NNP
cord-010027-r0tl01kq	134	8	,	,	,
cord-010027-r0tl01kq	134	9	Linköping	Linköping	NNP
cord-010027-r0tl01kq	134	10	,	,	,
cord-010027-r0tl01kq	134	11	Sweden	Sweden	NNP
cord-010027-r0tl01kq	134	12	This	this	DT
cord-010027-r0tl01kq	134	13	presentation	presentation	NN
cord-010027-r0tl01kq	134	14	will	will	MD
cord-010027-r0tl01kq	134	15	describe	describe	VB
cord-010027-r0tl01kq	134	16	the	the	DT
cord-010027-r0tl01kq	134	17	large	large	JJ
cord-010027-r0tl01kq	134	18	-	-	HYPH
cord-010027-r0tl01kq	134	19	scale	scale	NN
cord-010027-r0tl01kq	134	20	routine	routine	JJ
cord-010027-r0tl01kq	134	21	usage	usage	NN
cord-010027-r0tl01kq	134	22	of	of	IN
cord-010027-r0tl01kq	134	23	WSI	WSI	NNP
cord-010027-r0tl01kq	134	24	at	at	IN
cord-010027-r0tl01kq	134	25	Linköping	Linköping	NNP
cord-010027-r0tl01kq	134	26	University	University	NNP
cord-010027-r0tl01kq	134	27	Hospital	Hospital	NNP
cord-010027-r0tl01kq	134	28	,	,	,
cord-010027-r0tl01kq	134	29	Sweden	Sweden	NNP
cord-010027-r0tl01kq	134	30	.	.	.
cord-010027-r0tl01kq	135	1	Since	since	IN
cord-010027-r0tl01kq	135	2	2011	2011	CD
cord-010027-r0tl01kq	135	3	all	all	DT
cord-010027-r0tl01kq	135	4	histology	histology	NN
cord-010027-r0tl01kq	135	5	slides	slide	NNS
cord-010027-r0tl01kq	135	6	are	be	VBP
cord-010027-r0tl01kq	135	7	scanned	scan	VBN
cord-010027-r0tl01kq	135	8	,	,	,
cord-010027-r0tl01kq	135	9	amounting	amount	VBG
cord-010027-r0tl01kq	135	10	to	to	IN
cord-010027-r0tl01kq	135	11	more	more	JJR
cord-010027-r0tl01kq	135	12	than	than	IN
cord-010027-r0tl01kq	135	13	half	half	PDT
cord-010027-r0tl01kq	135	14	a	a	DT
cord-010027-r0tl01kq	135	15	million	million	CD
cord-010027-r0tl01kq	135	16	slides	slide	NNS
cord-010027-r0tl01kq	135	17	to	to	IN
cord-010027-r0tl01kq	135	18	date	date	NN
cord-010027-r0tl01kq	135	19	.	.	.
cord-010027-r0tl01kq	136	1	To	to	IN
cord-010027-r0tl01kq	136	2	a	a	DT
cord-010027-r0tl01kq	136	3	significant	significant	JJ
cord-010027-r0tl01kq	136	4	extent	extent	NN
cord-010027-r0tl01kq	136	5	the	the	DT
cord-010027-r0tl01kq	136	6	digital	digital	JJ
cord-010027-r0tl01kq	136	7	images	image	NNS
cord-010027-r0tl01kq	136	8	are	be	VBP
cord-010027-r0tl01kq	136	9	used	use	VBN
cord-010027-r0tl01kq	136	10	for	for	IN
cord-010027-r0tl01kq	136	11	primary	primary	JJ
cord-010027-r0tl01kq	136	12	review	review	NN
cord-010027-r0tl01kq	136	13	.	.	.
cord-010027-r0tl01kq	137	1	The	the	DT
cord-010027-r0tl01kq	137	2	initial	initial	JJ
cord-010027-r0tl01kq	137	3	implementation	implementation	NN
cord-010027-r0tl01kq	137	4	led	lead	VBD
cord-010027-r0tl01kq	137	5	to	to	IN
cord-010027-r0tl01kq	137	6	several	several	JJ
cord-010027-r0tl01kq	137	7	of	of	IN
cord-010027-r0tl01kq	137	8	the	the	DT
cord-010027-r0tl01kq	137	9	benefits	benefit	NNS
cord-010027-r0tl01kq	137	10	foreseen	foresee	VBN
cord-010027-r0tl01kq	137	11	with	with	IN
cord-010027-r0tl01kq	137	12	digital	digital	JJ
cord-010027-r0tl01kq	137	13	pathology	pathology	NN
cord-010027-r0tl01kq	137	14	,	,	,
cord-010027-r0tl01kq	137	15	but	but	CC
cord-010027-r0tl01kq	137	16	it	-PRON-	PRP
cord-010027-r0tl01kq	137	17	could	could	MD
cord-010027-r0tl01kq	137	18	also	also	RB
cord-010027-r0tl01kq	137	19	be	be	VB
cord-010027-r0tl01kq	137	20	concluded	conclude	VBN
cord-010027-r0tl01kq	137	21	that	that	IN
cord-010027-r0tl01kq	137	22	further	further	JJ
cord-010027-r0tl01kq	137	23	development	development	NN
cord-010027-r0tl01kq	137	24	was	be	VBD
cord-010027-r0tl01kq	137	25	needed	need	VBN
cord-010027-r0tl01kq	137	26	to	to	TO
cord-010027-r0tl01kq	137	27	unlock	unlock	VB
cord-010027-r0tl01kq	137	28	the	the	DT
cord-010027-r0tl01kq	137	29	full	full	JJ
cord-010027-r0tl01kq	137	30	potential	potential	NN
cord-010027-r0tl01kq	137	31	,	,	,
cord-010027-r0tl01kq	137	32	in	in	IN
cord-010027-r0tl01kq	137	33	particular	particular	JJ
cord-010027-r0tl01kq	137	34	within	within	IN
cord-010027-r0tl01kq	137	35	the	the	DT
cord-010027-r0tl01kq	137	36	IT	IT	NNP
cord-010027-r0tl01kq	137	37	solutions	solution	NNS
cord-010027-r0tl01kq	137	38	.	.	.
cord-010027-r0tl01kq	138	1	Therefore	therefore	RB
cord-010027-r0tl01kq	138	2	,	,	,
cord-010027-r0tl01kq	138	3	a	a	DT
cord-010027-r0tl01kq	138	4	consortium	consortium	NN
cord-010027-r0tl01kq	138	5	led	lead	VBN
cord-010027-r0tl01kq	138	6	by	by	IN
cord-010027-r0tl01kq	138	7	CMIV	CMIV	NNP
cord-010027-r0tl01kq	138	8	,	,	,
cord-010027-r0tl01kq	138	9	Linköping	Linköping	NNP
cord-010027-r0tl01kq	138	10	University	University	NNP
cord-010027-r0tl01kq	138	11	was	be	VBD
cord-010027-r0tl01kq	138	12	formed	form	VBN
cord-010027-r0tl01kq	138	13	in	in	IN
cord-010027-r0tl01kq	138	14	2012	2012	CD
cord-010027-r0tl01kq	138	15	to	to	TO
cord-010027-r0tl01kq	138	16	create	create	VB
cord-010027-r0tl01kq	138	17	innovations	innovation	NNS
cord-010027-r0tl01kq	138	18	for	for	IN
cord-010027-r0tl01kq	138	19	a	a	DT
cord-010027-r0tl01kq	138	20	new	new	JJ
cord-010027-r0tl01kq	138	21	generation	generation	NN
cord-010027-r0tl01kq	138	22	of	of	IN
cord-010027-r0tl01kq	138	23	digital	digital	JJ
cord-010027-r0tl01kq	138	24	pathology	pathology	NN
cord-010027-r0tl01kq	138	25	.	.	.
cord-010027-r0tl01kq	139	1	This	this	DT
cord-010027-r0tl01kq	139	2	triple	triple	JJ
cord-010027-r0tl01kq	139	3	helix	helix	NN
cord-010027-r0tl01kq	139	4	consortium	consortium	NN
cord-010027-r0tl01kq	139	5	also	also	RB
cord-010027-r0tl01kq	139	6	includes	include	VBZ
cord-010027-r0tl01kq	139	7	industry	industry	NN
cord-010027-r0tl01kq	139	8	and	and	CC
cord-010027-r0tl01kq	139	9	more	more	JJR
cord-010027-r0tl01kq	139	10	than	than	IN
cord-010027-r0tl01kq	139	11	half	half	NN
cord-010027-r0tl01kq	139	12	of	of	IN
cord-010027-r0tl01kq	139	13	Sweden	Sweden	NNP
cord-010027-r0tl01kq	139	14	's	's	POS
cord-010027-r0tl01kq	139	15	health	health	NN
cord-010027-r0tl01kq	139	16	care	care	NN
cord-010027-r0tl01kq	139	17	providers	provider	NNS
cord-010027-r0tl01kq	139	18	,	,	,
cord-010027-r0tl01kq	139	19	an	an	DT
cord-010027-r0tl01kq	139	20	engagement	engagement	NN
cord-010027-r0tl01kq	139	21	that	that	WDT
cord-010027-r0tl01kq	139	22	reflects	reflect	VBZ
cord-010027-r0tl01kq	139	23	the	the	DT
cord-010027-r0tl01kq	139	24	dominating	dominating	JJ
cord-010027-r0tl01kq	139	25	view	view	NN
cord-010027-r0tl01kq	139	26	in	in	IN
cord-010027-r0tl01kq	139	27	Swedish	swedish	JJ
cord-010027-r0tl01kq	139	28	pathology	pathology	NN
cord-010027-r0tl01kq	139	29	that	that	IN
cord-010027-r0tl01kq	139	30	large	large	JJ
cord-010027-r0tl01kq	139	31	-	-	HYPH
cord-010027-r0tl01kq	139	32	scale	scale	NN
cord-010027-r0tl01kq	139	33	adoption	adoption	NN
cord-010027-r0tl01kq	139	34	of	of	IN
cord-010027-r0tl01kq	139	35	WSI	wsi	JJ
cord-010027-r0tl01kq	139	36	practice	practice	NN
cord-010027-r0tl01kq	139	37	is	be	VBZ
cord-010027-r0tl01kq	139	38	possible	possible	JJ
cord-010027-r0tl01kq	139	39	and	and	CC
cord-010027-r0tl01kq	139	40	desirable	desirable	JJ
cord-010027-r0tl01kq	139	41	.	.	.
cord-010027-r0tl01kq	140	1	This	this	DT
cord-010027-r0tl01kq	140	2	talk	talk	NN
cord-010027-r0tl01kq	140	3	covers	cover	VBZ
cord-010027-r0tl01kq	140	4	the	the	DT
cord-010027-r0tl01kq	140	5	experiences	experience	NNS
cord-010027-r0tl01kq	140	6	made	make	VBN
cord-010027-r0tl01kq	140	7	during	during	IN
cord-010027-r0tl01kq	140	8	the	the	DT
cord-010027-r0tl01kq	140	9	initial	initial	JJ
cord-010027-r0tl01kq	140	10	digitization	digitization	NN
cord-010027-r0tl01kq	140	11	,	,	,
cord-010027-r0tl01kq	140	12	including	include	VBG
cord-010027-r0tl01kq	140	13	laboratory	laboratory	NN
cord-010027-r0tl01kq	140	14	process	process	NN
cord-010027-r0tl01kq	140	15	adjustments	adjustment	NNS
cord-010027-r0tl01kq	140	16	,	,	,
cord-010027-r0tl01kq	140	17	and	and	CC
cord-010027-r0tl01kq	140	18	the	the	DT
cord-010027-r0tl01kq	140	19	later	later	JJ
cord-010027-r0tl01kq	140	20	additions	addition	NNS
cord-010027-r0tl01kq	140	21	to	to	IN
cord-010027-r0tl01kq	140	22	the	the	DT
cord-010027-r0tl01kq	140	23	digital	digital	JJ
cord-010027-r0tl01kq	140	24	pathology	pathology	NN
cord-010027-r0tl01kq	140	25	toolbox	toolbox	NN
cord-010027-r0tl01kq	140	26	accomplished	accomplish	VBN
cord-010027-r0tl01kq	140	27	by	by	IN
cord-010027-r0tl01kq	140	28	the	the	DT
cord-010027-r0tl01kq	140	29	ongoing	ongoing	JJ
cord-010027-r0tl01kq	140	30	innovation	innovation	NN
cord-010027-r0tl01kq	140	31	project	project	NN
cord-010027-r0tl01kq	140	32	.	.	.
cord-010027-r0tl01kq	141	1	Apart	apart	RB
cord-010027-r0tl01kq	141	2	from	from	IN
cord-010027-r0tl01kq	141	3	obvious	obvious	JJ
cord-010027-r0tl01kq	141	4	targets	target	NNS
cord-010027-r0tl01kq	141	5	such	such	JJ
cord-010027-r0tl01kq	141	6	as	as	IN
cord-010027-r0tl01kq	141	7	the	the	DT
cord-010027-r0tl01kq	141	8	pathologists	pathologist	NNS
cord-010027-r0tl01kq	141	9	'	'	POS
cord-010027-r0tl01kq	141	10	workstation	workstation	NN
cord-010027-r0tl01kq	141	11	,	,	,
cord-010027-r0tl01kq	141	12	the	the	DT
cord-010027-r0tl01kq	141	13	developments	development	NNS
cord-010027-r0tl01kq	141	14	also	also	RB
cord-010027-r0tl01kq	141	15	touch	touch	VBP
cord-010027-r0tl01kq	141	16	upon	upon	IN
cord-010027-r0tl01kq	141	17	other	other	JJ
cord-010027-r0tl01kq	141	18	areas	area	NNS
cord-010027-r0tl01kq	141	19	including	include	VBG
cord-010027-r0tl01kq	141	20	grossing	gross	VBG
cord-010027-r0tl01kq	141	21	and	and	CC
cord-010027-r0tl01kq	141	22	enterprise	enterprise	NN
cord-010027-r0tl01kq	141	23	image	image	NN
cord-010027-r0tl01kq	141	24	management	management	NN
cord-010027-r0tl01kq	141	25	.	.	.
cord-010027-r0tl01kq	142	1			.
cord-010027-r0tl01kq	143	1	Digital	Digital	NNP
cord-010027-r0tl01kq	143	2	Pathology	Pathology	NNP
cord-010027-r0tl01kq	144	1	-Are	-Are	:
cord-010027-r0tl01kq	145	1	We	-PRON-	PRP
cord-010027-r0tl01kq	145	2	There	there	RB
cord-010027-r0tl01kq	146	1	Yet	yet	RB
cord-010027-r0tl01kq	146	2	?	?	.
cord-010027-r0tl01kq	147	1	P	p	NN
cord-010027-r0tl01kq	147	2	SM	SM	NNP
cord-010027-r0tl01kq	147	3	Hewitt	Hewitt	NNP
cord-010027-r0tl01kq	147	4	National	National	NNP
cord-010027-r0tl01kq	147	5	Cancer	Cancer	NNP
cord-010027-r0tl01kq	147	6	Institute	Institute	NNP
cord-010027-r0tl01kq	147	7	,	,	,
cord-010027-r0tl01kq	147	8	Bethesda	Bethesda	NNP
cord-010027-r0tl01kq	147	9	,	,	,
cord-010027-r0tl01kq	147	10	Maryland	Maryland	NNP
cord-010027-r0tl01kq	147	11	,	,	,
cord-010027-r0tl01kq	147	12	USA	USA	NNP
cord-010027-r0tl01kq	148	1	The	the	DT
cord-010027-r0tl01kq	148	2	implementation	implementation	NN
cord-010027-r0tl01kq	148	3	of	of	IN
cord-010027-r0tl01kq	148	4	whole	whole	JJ
cord-010027-r0tl01kq	148	5	slide	slide	NN
cord-010027-r0tl01kq	148	6	imaging	imaging	NN
cord-010027-r0tl01kq	148	7	for	for	IN
cord-010027-r0tl01kq	148	8	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	148	9	histopathology	histopathology	NN
cord-010027-r0tl01kq	148	10	is	be	VBZ
cord-010027-r0tl01kq	148	11	far	far	RB
cord-010027-r0tl01kq	148	12	more	more	RBR
cord-010027-r0tl01kq	148	13	complex	complex	JJ
cord-010027-r0tl01kq	148	14	than	than	IN
cord-010027-r0tl01kq	148	15	connecting	connect	VBG
cord-010027-r0tl01kq	148	16	an	an	DT
cord-010027-r0tl01kq	148	17	instrument	instrument	NN
cord-010027-r0tl01kq	148	18	to	to	IN
cord-010027-r0tl01kq	148	19	a	a	DT
cord-010027-r0tl01kq	148	20	server	server	NN
cord-010027-r0tl01kq	148	21	,	,	,
cord-010027-r0tl01kq	148	22	and	and	CC
cord-010027-r0tl01kq	148	23	placing	place	VBG
cord-010027-r0tl01kq	148	24	a	a	DT
cord-010027-r0tl01kq	148	25	computer	computer	NN
cord-010027-r0tl01kq	148	26	on	on	IN
cord-010027-r0tl01kq	148	27	a	a	DT
cord-010027-r0tl01kq	148	28	pathologist	pathologist	NN
cord-010027-r0tl01kq	148	29	's	's	POS
cord-010027-r0tl01kq	148	30	desk	desk	NN
cord-010027-r0tl01kq	148	31	.	.	.
cord-010027-r0tl01kq	149	1	The	the	DT
cord-010027-r0tl01kq	149	2	technology	technology	NN
cord-010027-r0tl01kq	149	3	is	be	VBZ
cord-010027-r0tl01kq	149	4	additive	additive	NN
cord-010027-r0tl01kq	149	5	to	to	IN
cord-010027-r0tl01kq	149	6	the	the	DT
cord-010027-r0tl01kq	149	7	histology	histology	NN
cord-010027-r0tl01kq	149	8	workflow	workflow	NN
cord-010027-r0tl01kq	149	9	,	,	,
cord-010027-r0tl01kq	149	10	with	with	IN
cord-010027-r0tl01kq	149	11	additional	additional	JJ
cord-010027-r0tl01kq	149	12	cost	cost	NN
cord-010027-r0tl01kq	149	13	beyond	beyond	IN
cord-010027-r0tl01kq	149	14	the	the	DT
cord-010027-r0tl01kq	149	15	current	current	JJ
cord-010027-r0tl01kq	149	16	practice	practice	NN
cord-010027-r0tl01kq	149	17	of	of	IN
cord-010027-r0tl01kq	149	18	review	review	NN
cord-010027-r0tl01kq	149	19	with	with	IN
cord-010027-r0tl01kq	149	20	a	a	DT
cord-010027-r0tl01kq	149	21	microscope	microscope	NN
cord-010027-r0tl01kq	149	22	.	.	.
cord-010027-r0tl01kq	150	1	The	the	DT
cord-010027-r0tl01kq	150	2	adoption	adoption	NN
cord-010027-r0tl01kq	150	3	of	of	IN
cord-010027-r0tl01kq	150	4	Digital	Digital	NNP
cord-010027-r0tl01kq	150	5	Pathology	Pathology	NNP
cord-010027-r0tl01kq	150	6	for	for	IN
cord-010027-r0tl01kq	150	7	histomorphologic	histomorphologic	JJ
cord-010027-r0tl01kq	150	8	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	150	9	requires	require	VBZ
cord-010027-r0tl01kq	150	10	the	the	DT
cord-010027-r0tl01kq	150	11	restructuring	restructuring	NN
cord-010027-r0tl01kq	150	12	of	of	IN
cord-010027-r0tl01kq	150	13	the	the	DT
cord-010027-r0tl01kq	150	14	workflow	workflow	NN
cord-010027-r0tl01kq	150	15	,	,	,
cord-010027-r0tl01kq	150	16	additional	additional	JJ
cord-010027-r0tl01kq	150	17	technology	technology	NN
cord-010027-r0tl01kq	150	18	advances	advance	VBZ
cord-010027-r0tl01kq	150	19	beyond	beyond	IN
cord-010027-r0tl01kq	150	20	the	the	DT
cord-010027-r0tl01kq	150	21	imaging	imaging	NN
cord-010027-r0tl01kq	150	22	instrument	instrument	NN
cord-010027-r0tl01kq	150	23	,	,	,
cord-010027-r0tl01kq	150	24	and	and	CC
cord-010027-r0tl01kq	150	25	development	development	NN
cord-010027-r0tl01kq	150	26	of	of	IN
cord-010027-r0tl01kq	150	27	new	new	JJ
cord-010027-r0tl01kq	150	28	tools	tool	NNS
cord-010027-r0tl01kq	150	29	to	to	TO
cord-010027-r0tl01kq	150	30	assist	assist	VB
cord-010027-r0tl01kq	150	31	the	the	DT
cord-010027-r0tl01kq	150	32	pathologist	pathologist	NN
cord-010027-r0tl01kq	150	33	.	.	.
cord-010027-r0tl01kq	151	1	The	the	DT
cord-010027-r0tl01kq	151	2	end	end	NN
cord-010027-r0tl01kq	151	3	goal	goal	NN
cord-010027-r0tl01kq	151	4	is	be	VBZ
cord-010027-r0tl01kq	151	5	to	to	TO
cord-010027-r0tl01kq	151	6	improve	improve	VB
cord-010027-r0tl01kq	151	7	pathologist	pathologist	NN
cord-010027-r0tl01kq	151	8	's	's	POS
cord-010027-r0tl01kq	151	9	productivity	productivity	NN
cord-010027-r0tl01kq	151	10	and	and	CC
cord-010027-r0tl01kq	151	11	provide	provide	VB
cord-010027-r0tl01kq	151	12	additional	additional	JJ
cord-010027-r0tl01kq	151	13	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	151	14	information	information	NN
cord-010027-r0tl01kq	151	15	.	.	.
cord-010027-r0tl01kq	152	1	Digital	Digital	NNP
cord-010027-r0tl01kq	152	2	Pathology	Pathology	NNP
cord-010027-r0tl01kq	152	3	,	,	,
cord-010027-r0tl01kq	152	4	to	to	TO
cord-010027-r0tl01kq	152	5	succeed	succeed	VB
cord-010027-r0tl01kq	152	6	must	must	MD
cord-010027-r0tl01kq	152	7	become	become	VB
cord-010027-r0tl01kq	152	8	a	a	DT
cord-010027-r0tl01kq	152	9	value	value	NN
cord-010027-r0tl01kq	152	10	-	-	HYPH
cord-010027-r0tl01kq	152	11	added	add	VBN
cord-010027-r0tl01kq	152	12	proposition	proposition	NN
cord-010027-r0tl01kq	152	13	.	.	.
cord-010027-r0tl01kq	153	1	The	the	DT
cord-010027-r0tl01kq	153	2	adoption	adoption	NN
cord-010027-r0tl01kq	153	3	of	of	IN
cord-010027-r0tl01kq	153	4	Digital	Digital	NNP
cord-010027-r0tl01kq	153	5	Pathology	Pathology	NNP
cord-010027-r0tl01kq	153	6	requires	require	VBZ
cord-010027-r0tl01kq	153	7	:	:	:
cord-010027-r0tl01kq	153	8	1)Improvements	1)improvements	CD
cord-010027-r0tl01kq	153	9	in	in	IN
cord-010027-r0tl01kq	153	10	scanner	scanner	NN
cord-010027-r0tl01kq	153	11	performance	performance	NN
cord-010027-r0tl01kq	153	12	as	as	IN
cord-010027-r0tl01kq	153	13	measured	measure	VBN
cord-010027-r0tl01kq	153	14	by	by	IN
cord-010027-r0tl01kq	153	15	defined	define	VBN
cord-010027-r0tl01kq	153	16	quality	quality	NN
cord-010027-r0tl01kq	153	17	metrics	metric	NNS
cord-010027-r0tl01kq	153	18	.	.	.
cord-010027-r0tl01kq	154	1	2)Advancement	2)advancement	CD
cord-010027-r0tl01kq	154	2	in	in	IN
cord-010027-r0tl01kq	154	3	server	server	NN
cord-010027-r0tl01kq	154	4	and	and	CC
cord-010027-r0tl01kq	154	5	networks	network	NNS
cord-010027-r0tl01kq	154	6	to	to	TO
cord-010027-r0tl01kq	154	7	distribute	distribute	VB
cord-010027-r0tl01kq	154	8	images	image	NNS
cord-010027-r0tl01kq	154	9	to	to	IN
cord-010027-r0tl01kq	154	10	the	the	DT
cord-010027-r0tl01kq	154	11	desktop	desktop	NN
cord-010027-r0tl01kq	154	12	efficiently	efficiently	RB
cord-010027-r0tl01kq	154	13	.	.	.
cord-010027-r0tl01kq	155	1	3)Software	3)software	CD
cord-010027-r0tl01kq	155	2	to	to	TO
cord-010027-r0tl01kq	155	3	facilitate	facilitate	VB
cord-010027-r0tl01kq	155	4	review	review	NN
cord-010027-r0tl01kq	155	5	and	and	CC
cord-010027-r0tl01kq	155	6	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	155	7	,	,	,
cord-010027-r0tl01kq	155	8	beyond	beyond	IN
cord-010027-r0tl01kq	155	9	presenting	present	VBG
cord-010027-r0tl01kq	155	10	only	only	RB
cord-010027-r0tl01kq	155	11	and	and	CC
cord-010027-r0tl01kq	155	12	image	image	NN
cord-010027-r0tl01kq	155	13	of	of	IN
cord-010027-r0tl01kq	155	14	the	the	DT
cord-010027-r0tl01kq	155	15	slide	slide	NN
cord-010027-r0tl01kq	155	16	.	.	.
cord-010027-r0tl01kq	156	1	Evolution	evolution	NN
cord-010027-r0tl01kq	156	2	of	of	IN
cord-010027-r0tl01kq	156	3	the	the	DT
cord-010027-r0tl01kq	156	4	current	current	JJ
cord-010027-r0tl01kq	156	5	technologies	technology	NNS
cord-010027-r0tl01kq	156	6	is	be	VBZ
cord-010027-r0tl01kq	156	7	required	require	VBN
cord-010027-r0tl01kq	156	8	to	to	TO
cord-010027-r0tl01kq	156	9	provide	provide	VB
cord-010027-r0tl01kq	156	10	an	an	DT
cord-010027-r0tl01kq	156	11	economic	economic	JJ
cord-010027-r0tl01kq	156	12	impetus	impetus	NN
cord-010027-r0tl01kq	156	13	for	for	IN
cord-010027-r0tl01kq	156	14	widespread	widespread	JJ
cord-010027-r0tl01kq	156	15	adoption	adoption	NN
cord-010027-r0tl01kq	156	16	and	and	CC
cord-010027-r0tl01kq	156	17	use	use	NN
cord-010027-r0tl01kq	156	18	of	of	IN
cord-010027-r0tl01kq	156	19	Digital	Digital	NNP
cord-010027-r0tl01kq	156	20	Pathology	Pathology	NNP
cord-010027-r0tl01kq	156	21	in	in	IN
cord-010027-r0tl01kq	156	22	the	the	DT
cord-010027-r0tl01kq	156	23	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	156	24	setting	setting	NN
cord-010027-r0tl01kq	156	25	.	.	.
cord-010027-r0tl01kq	157	1	To	to	IN
cord-010027-r0tl01kq	157	2	a	a	DT
cord-010027-r0tl01kq	157	3	significant	significant	JJ
cord-010027-r0tl01kq	157	4	extent	extent	NN
cord-010027-r0tl01kq	157	5	,	,	,
cord-010027-r0tl01kq	157	6	the	the	DT
cord-010027-r0tl01kq	157	7	distinction	distinction	NN
cord-010027-r0tl01kq	157	8	between	between	IN
cord-010027-r0tl01kq	157	9	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	157	10	naevi	naevus	NNS
cord-010027-r0tl01kq	157	11	and	and	CC
cord-010027-r0tl01kq	157	12	malignant	malignant	JJ
cord-010027-r0tl01kq	157	13	melanomas	melanoma	NNS
cord-010027-r0tl01kq	157	14	is	be	VBZ
cord-010027-r0tl01kq	157	15	based	base	VBN
cord-010027-r0tl01kq	157	16	on	on	IN
cord-010027-r0tl01kq	157	17	tissue	tissue	NN
cord-010027-r0tl01kq	157	18	architecture	architecture	NN
cord-010027-r0tl01kq	157	19	.	.	.
cord-010027-r0tl01kq	158	1	Amongst	amongst	IN
cord-010027-r0tl01kq	158	2	the	the	DT
cord-010027-r0tl01kq	158	3	best	well	RBS
cord-010027-r0tl01kq	158	4	known	know	VBN
cord-010027-r0tl01kq	158	5	architectural	architectural	JJ
cord-010027-r0tl01kq	158	6	features	feature	NNS
cord-010027-r0tl01kq	158	7	pointing	point	VBG
cord-010027-r0tl01kq	158	8	to	to	IN
cord-010027-r0tl01kq	158	9	malignancy	malignancy	NN
cord-010027-r0tl01kq	158	10	are	be	VBP
cord-010027-r0tl01kq	158	11	absence	absence	NN
cord-010027-r0tl01kq	158	12	of	of	IN
cord-010027-r0tl01kq	158	13	lesional	lesional	JJ
cord-010027-r0tl01kq	158	14	symmetry	symmetry	NN
cord-010027-r0tl01kq	158	15	and	and	CC
cord-010027-r0tl01kq	158	16	maturation	maturation	NN
cord-010027-r0tl01kq	158	17	,	,	,
cord-010027-r0tl01kq	158	18	and	and	CC
cord-010027-r0tl01kq	158	19	presence	presence	NN
cord-010027-r0tl01kq	158	20	of	of	IN
cord-010027-r0tl01kq	158	21	melanocyte	melanocyte	NN
cord-010027-r0tl01kq	158	22	ascent	ascent	NN
cord-010027-r0tl01kq	158	23	.	.	.
cord-010027-r0tl01kq	159	1	However	however	RB
cord-010027-r0tl01kq	159	2	,	,	,
cord-010027-r0tl01kq	159	3	each	each	DT
cord-010027-r0tl01kq	159	4	of	of	IN
cord-010027-r0tl01kq	159	5	these	these	DT
cord-010027-r0tl01kq	159	6	three	three	CD
cord-010027-r0tl01kq	159	7	features	feature	NNS
cord-010027-r0tl01kq	159	8	has	have	VBZ
cord-010027-r0tl01kq	159	9	significant	significant	JJ
cord-010027-r0tl01kq	159	10	pitfalls	pitfall	NNS
cord-010027-r0tl01kq	159	11	.	.	.
cord-010027-r0tl01kq	160	1	As	as	IN
cord-010027-r0tl01kq	160	2	a	a	DT
cord-010027-r0tl01kq	160	3	rule	rule	NN
cord-010027-r0tl01kq	160	4	,	,	,
cord-010027-r0tl01kq	160	5	naevi	naevus	NNS
cord-010027-r0tl01kq	160	6	are	be	VBP
cord-010027-r0tl01kq	160	7	'	'	``
cord-010027-r0tl01kq	160	8	roughly	roughly	RB
cord-010027-r0tl01kq	160	9	symmetrical	symmetrical	JJ
cord-010027-r0tl01kq	160	10	'	'	''
cord-010027-r0tl01kq	160	11	and	and	CC
cord-010027-r0tl01kq	160	12	melanomas	melanoma	NNS
cord-010027-r0tl01kq	160	13	are	be	VBP
cord-010027-r0tl01kq	160	14	not	not	RB
cord-010027-r0tl01kq	160	15	,	,	,
cord-010027-r0tl01kq	160	16	but	but	CC
cord-010027-r0tl01kq	160	17	there	there	EX
cord-010027-r0tl01kq	160	18	are	be	VBP
cord-010027-r0tl01kq	160	19	asymmetrical	asymmetrical	JJ
cord-010027-r0tl01kq	160	20	naevi	naevus	NNS
cord-010027-r0tl01kq	160	21	(	(	-LRB-
cord-010027-r0tl01kq	160	22	traumatized	traumatize	VBN
cord-010027-r0tl01kq	160	23	naevi	naevus	NNS
cord-010027-r0tl01kq	160	24	,	,	,
cord-010027-r0tl01kq	160	25	most	most	RBS
cord-010027-r0tl01kq	160	26	larger	large	JJR
cord-010027-r0tl01kq	160	27	congenital	congenital	JJ
cord-010027-r0tl01kq	160	28	naevi	naevus	NNS
cord-010027-r0tl01kq	160	29	;	;	:
cord-010027-r0tl01kq	160	30	some	some	DT
cord-010027-r0tl01kq	160	31	combined	combine	VBN
cord-010027-r0tl01kq	160	32	naevi	naevi	NN
cord-010027-r0tl01kq	160	33	;	;	:
cord-010027-r0tl01kq	160	34	some	some	DT
cord-010027-r0tl01kq	160	35	large	large	JJ
cord-010027-r0tl01kq	160	36	acral	acral	JJ
cord-010027-r0tl01kq	160	37	and	and	CC
cord-010027-r0tl01kq	160	38	genital	genital	JJ
cord-010027-r0tl01kq	160	39	naevi	naevus	NNS
cord-010027-r0tl01kq	160	40	)	)	-RRB-
cord-010027-r0tl01kq	160	41	and	and	CC
cord-010027-r0tl01kq	160	42	symmetrical	symmetrical	JJ
cord-010027-r0tl01kq	160	43	melanomas	melanoma	NNS
cord-010027-r0tl01kq	160	44	(	(	-LRB-
cord-010027-r0tl01kq	160	45	including	include	VBG
cord-010027-r0tl01kq	160	46	many	many	JJ
cord-010027-r0tl01kq	160	47	small	small	JJ
cord-010027-r0tl01kq	160	48	melanomas	melanoma	NNS
cord-010027-r0tl01kq	160	49	,	,	,
cord-010027-r0tl01kq	160	50	especially	especially	RB
cord-010027-r0tl01kq	160	51	small	small	JJ
cord-010027-r0tl01kq	160	52	nodular	nodular	JJ
cord-010027-r0tl01kq	160	53	melanomas	melanoma	NNS
cord-010027-r0tl01kq	160	54	;	;	,
cord-010027-r0tl01kq	160	55	some	some	DT
cord-010027-r0tl01kq	160	56	spitzoid	spitzoid	FW
cord-010027-r0tl01kq	160	57	melanomas	melanoma	NNS
cord-010027-r0tl01kq	160	58	)	)	-RRB-
cord-010027-r0tl01kq	160	59	.	.	.
cord-010027-r0tl01kq	161	1	In	in	IN
cord-010027-r0tl01kq	161	2	addition	addition	NN
cord-010027-r0tl01kq	161	3	,	,	,
cord-010027-r0tl01kq	161	4	it	-PRON-	PRP
cord-010027-r0tl01kq	161	5	is	be	VBZ
cord-010027-r0tl01kq	161	6	not	not	RB
cord-010027-r0tl01kq	161	7	always	always	RB
cord-010027-r0tl01kq	161	8	clear	clear	JJ
cord-010027-r0tl01kq	161	9	whether	whether	IN
cord-010027-r0tl01kq	161	10	a	a	DT
cord-010027-r0tl01kq	161	11	lesion	lesion	NN
cord-010027-r0tl01kq	161	12	should	should	MD
cord-010027-r0tl01kq	161	13	be	be	VB
cord-010027-r0tl01kq	161	14	considered	consider	VBN
cord-010027-r0tl01kq	161	15	'	'	``
cord-010027-r0tl01kq	161	16	roughly	roughly	RB
cord-010027-r0tl01kq	161	17	symmetrical	symmetrical	JJ
cord-010027-r0tl01kq	161	18	'	'	''
cord-010027-r0tl01kq	161	19	or	or	CC
cord-010027-r0tl01kq	161	20	not	not	RB
cord-010027-r0tl01kq	161	21	.	.	.
cord-010027-r0tl01kq	162	1	I	-PRON-	PRP
cord-010027-r0tl01kq	162	2	suspect	suspect	VBP
cord-010027-r0tl01kq	162	3	that	that	IN
cord-010027-r0tl01kq	162	4	not	not	RB
cord-010027-r0tl01kq	162	5	uncommonly	uncommonly	RB
cord-010027-r0tl01kq	162	6	,	,	,
cord-010027-r0tl01kq	162	7	a	a	DT
cord-010027-r0tl01kq	162	8	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	162	9	is	be	VBZ
cord-010027-r0tl01kq	162	10	reached	reach	VBN
cord-010027-r0tl01kq	162	11	first	first	RB
cord-010027-r0tl01kq	162	12	,	,	,
cord-010027-r0tl01kq	162	13	and	and	CC
cord-010027-r0tl01kq	162	14	the	the	DT
cord-010027-r0tl01kq	162	15	verdict	verdict	NN
cord-010027-r0tl01kq	162	16	regarding	regard	VBG
cord-010027-r0tl01kq	162	17	symmetry	symmetry	NN
cord-010027-r0tl01kq	162	18	is	be	VBZ
cord-010027-r0tl01kq	162	19	adjusted	adjust	VBN
cord-010027-r0tl01kq	162	20	according	accord	VBG
cord-010027-r0tl01kq	162	21	to	to	IN
cord-010027-r0tl01kq	162	22	that	that	DT
cord-010027-r0tl01kq	162	23	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	162	24	.	.	.
cord-010027-r0tl01kq	163	1	Similar	similar	JJ
cord-010027-r0tl01kq	163	2	caveats	caveat	NNS
cord-010027-r0tl01kq	163	3	relate	relate	VBP
cord-010027-r0tl01kq	163	4	to	to	IN
cord-010027-r0tl01kq	163	5	absence	absence	NN
cord-010027-r0tl01kq	163	6	of	of	IN
cord-010027-r0tl01kq	163	7	maturation	maturation	NN
cord-010027-r0tl01kq	163	8	as	as	IN
cord-010027-r0tl01kq	163	9	an	an	DT
cord-010027-r0tl01kq	163	10	indicator	indicator	NN
cord-010027-r0tl01kq	163	11	of	of	IN
cord-010027-r0tl01kq	163	12	malignancy	malignancy	NN
cord-010027-r0tl01kq	163	13	.	.	.
cord-010027-r0tl01kq	164	1	It	-PRON-	PRP
cord-010027-r0tl01kq	164	2	is	be	VBZ
cord-010027-r0tl01kq	164	3	seen	see	VBN
cord-010027-r0tl01kq	164	4	in	in	IN
cord-010027-r0tl01kq	164	5	blue	blue	JJ
cord-010027-r0tl01kq	164	6	naevi	naevus	NNS
cord-010027-r0tl01kq	164	7	and	and	CC
cord-010027-r0tl01kq	164	8	all	all	PDT
cord-010027-r0tl01kq	164	9	its	-PRON-	PRP$
cord-010027-r0tl01kq	164	10	variants	variant	NNS
cord-010027-r0tl01kq	164	11	;	;	:
cord-010027-r0tl01kq	164	12	deep	deep	JJ
cord-010027-r0tl01kq	164	13	penetrating	penetrating	JJ
cord-010027-r0tl01kq	164	14	naevi	naevi	NN
cord-010027-r0tl01kq	164	15	;	;	:
cord-010027-r0tl01kq	164	16	some	some	DT
cord-010027-r0tl01kq	164	17	BAP1	BAP1	NNP
cord-010027-r0tl01kq	164	18	naevi	naevi	NN
cord-010027-r0tl01kq	164	19	.	.	.
cord-010027-r0tl01kq	165	1	Melanomas	melanoma	NNS
cord-010027-r0tl01kq	165	2	not	not	RB
cord-010027-r0tl01kq	165	3	uncommonly	uncommonly	RB
cord-010027-r0tl01kq	165	4	feature	feature	NN
cord-010027-r0tl01kq	165	5	smaller	small	JJR
cord-010027-r0tl01kq	165	6	cells	cell	NNS
cord-010027-r0tl01kq	165	7	in	in	IN
cord-010027-r0tl01kq	165	8	their	-PRON-	PRP$
cord-010027-r0tl01kq	165	9	deeper	deep	JJR
cord-010027-r0tl01kq	165	10	parts	part	NNS
cord-010027-r0tl01kq	165	11	,	,	,
cord-010027-r0tl01kq	165	12	or	or	CC
cord-010027-r0tl01kq	165	13	there	there	EX
cord-010027-r0tl01kq	165	14	may	may	MD
cord-010027-r0tl01kq	165	15	be	be	VB
cord-010027-r0tl01kq	165	16	an	an	DT
cord-010027-r0tl01kq	165	17	underlying	underlie	VBG
cord-010027-r0tl01kq	165	18	naevus	naevus	NN
cord-010027-r0tl01kq	165	19	remnant	remnant	NN
cord-010027-r0tl01kq	165	20	with	with	IN
cord-010027-r0tl01kq	165	21	smaller	small	JJR
cord-010027-r0tl01kq	165	22	cells	cell	NNS
cord-010027-r0tl01kq	165	23	.	.	.
cord-010027-r0tl01kq	166	1	Naevi	Naevi	NNP
cord-010027-r0tl01kq	166	2	with	with	IN
cord-010027-r0tl01kq	166	3	ascent	ascent	NN
cord-010027-r0tl01kq	166	4	include	include	VBP
cord-010027-r0tl01kq	166	5	many	many	JJ
cord-010027-r0tl01kq	166	6	Spitz	Spitz	NNP
cord-010027-r0tl01kq	166	7	naevi	naevus	NNS
cord-010027-r0tl01kq	166	8	;	;	:
cord-010027-r0tl01kq	166	9	Reed	Reed	NNP
cord-010027-r0tl01kq	166	10	naevi	naevi	NNP
cord-010027-r0tl01kq	166	11	;	;	:
cord-010027-r0tl01kq	166	12	some	some	DT
cord-010027-r0tl01kq	166	13	naevi	naevus	NNS
cord-010027-r0tl01kq	166	14	in	in	IN
cord-010027-r0tl01kq	166	15	early	early	JJ
cord-010027-r0tl01kq	166	16	infancy	infancy	NN
cord-010027-r0tl01kq	166	17	;	;	,
cord-010027-r0tl01kq	166	18	traumatized	traumatize	VBN
cord-010027-r0tl01kq	166	19	naevi	naevi	NNP
cord-010027-r0tl01kq	166	20	;	;	:
cord-010027-r0tl01kq	166	21	naevi	naevi	NNP
cord-010027-r0tl01kq	166	22	of	of	IN
cord-010027-r0tl01kq	166	23	acral	acral	JJ
cord-010027-r0tl01kq	166	24	skin	skin	NN
cord-010027-r0tl01kq	166	25	.	.	.
cord-010027-r0tl01kq	167	1	Over	over	IN
cord-010027-r0tl01kq	167	2	-	-	HYPH
cord-010027-r0tl01kq	167	3	interpretation	interpretation	NN
cord-010027-r0tl01kq	167	4	of	of	IN
cord-010027-r0tl01kq	167	5	ascent	ascent	NN
cord-010027-r0tl01kq	167	6	may	may	MD
cord-010027-r0tl01kq	167	7	result	result	VB
cord-010027-r0tl01kq	167	8	from	from	IN
cord-010027-r0tl01kq	167	9	inexperience	inexperience	NN
cord-010027-r0tl01kq	167	10	with	with	IN
cord-010027-r0tl01kq	167	11	Melan	Melan	NNP
cord-010027-r0tl01kq	167	12	-	-	HYPH
cord-010027-r0tl01kq	167	13	A	A	NNP
cord-010027-r0tl01kq	167	14	and	and	CC
cord-010027-r0tl01kq	167	15	some	some	DT
cord-010027-r0tl01kq	167	16	other	other	JJ
cord-010027-r0tl01kq	167	17	immune	immune	JJ
cord-010027-r0tl01kq	167	18	stains	stain	NNS
cord-010027-r0tl01kq	167	19	.	.	.
cord-010027-r0tl01kq	168	1	Melanomas	melanoma	NNS
cord-010027-r0tl01kq	168	2	devoid	devoid	JJ
cord-010027-r0tl01kq	168	3	of	of	IN
cord-010027-r0tl01kq	168	4	ascending	ascend	VBG
cord-010027-r0tl01kq	168	5	melanoma	melanoma	NN
cord-010027-r0tl01kq	168	6	cells	cell	NNS
cord-010027-r0tl01kq	168	7	comprise	comprise	VBP
cord-010027-r0tl01kq	168	8	a	a	DT
cord-010027-r0tl01kq	168	9	wide	wide	JJ
cord-010027-r0tl01kq	168	10	variety	variety	NN
cord-010027-r0tl01kq	168	11	of	of	IN
cord-010027-r0tl01kq	168	12	subtypes	subtype	NNS
cord-010027-r0tl01kq	168	13	including	include	VBG
cord-010027-r0tl01kq	168	14	,	,	,
cord-010027-r0tl01kq	168	15	desmoplastic	desmoplastic	JJ
cord-010027-r0tl01kq	168	16	melanomas	melanoma	NNS
cord-010027-r0tl01kq	168	17	and	and	CC
cord-010027-r0tl01kq	168	18	,	,	,
cord-010027-r0tl01kq	168	19	vexingly	vexingly	RB
cord-010027-r0tl01kq	168	20	,	,	,
cord-010027-r0tl01kq	168	21	some	some	DT
cord-010027-r0tl01kq	168	22	spitzoid	spitzoid	NN
cord-010027-r0tl01kq	168	23	melanomas	melanoma	NNS
cord-010027-r0tl01kq	168	24	.	.	.
cord-010027-r0tl01kq	169	1	These	these	DT
cord-010027-r0tl01kq	169	2	architectural	architectural	JJ
cord-010027-r0tl01kq	169	3	features	feature	NNS
cord-010027-r0tl01kq	169	4	must	must	MD
cord-010027-r0tl01kq	169	5	,	,	,
cord-010027-r0tl01kq	169	6	therefore	therefore	RB
cord-010027-r0tl01kq	169	7	,	,	,
cord-010027-r0tl01kq	169	8	be	be	VB
cord-010027-r0tl01kq	169	9	evaluated	evaluate	VBN
cord-010027-r0tl01kq	169	10	in	in	IN
cord-010027-r0tl01kq	169	11	the	the	DT
cord-010027-r0tl01kq	169	12	context	context	NN
cord-010027-r0tl01kq	169	13	of	of	IN
cord-010027-r0tl01kq	169	14	all	all	DT
cord-010027-r0tl01kq	169	15	other	other	JJ
cord-010027-r0tl01kq	169	16	findings	finding	NNS
cord-010027-r0tl01kq	169	17	,	,	,
cord-010027-r0tl01kq	169	18	and	and	CC
cord-010027-r0tl01kq	169	19	with	with	IN
cord-010027-r0tl01kq	169	20	a	a	DT
cord-010027-r0tl01kq	169	21	'	'	``
cord-010027-r0tl01kq	169	22	splitter	splitter	NN
cord-010027-r0tl01kq	169	23	's	's	POS
cord-010027-r0tl01kq	169	24	'	'	''
cord-010027-r0tl01kq	169	25	mind	mind	NN
cord-010027-r0tl01kq	169	26	set	set	VBN
cord-010027-r0tl01kq	169	27	,	,	,
cord-010027-r0tl01kq	169	28	taking	take	VBG
cord-010027-r0tl01kq	169	29	into	into	IN
cord-010027-r0tl01kq	169	30	account	account	NN
cord-010027-r0tl01kq	169	31	the	the	DT
cord-010027-r0tl01kq	169	32	individual	individual	JJ
cord-010027-r0tl01kq	169	33	characteristics	characteristic	NNS
cord-010027-r0tl01kq	169	34	of	of	IN
cord-010027-r0tl01kq	169	35	the	the	DT
cord-010027-r0tl01kq	169	36	specific	specific	JJ
cord-010027-r0tl01kq	169	37	naevus	naevus	NN
cord-010027-r0tl01kq	169	38	and	and	CC
cord-010027-r0tl01kq	169	39	melanoma	melanoma	NN
cord-010027-r0tl01kq	169	40	variants	variant	NNS
cord-010027-r0tl01kq	169	41	that	that	WDT
cord-010027-r0tl01kq	169	42	are	be	VBP
cord-010027-r0tl01kq	169	43	of	of	IN
cord-010027-r0tl01kq	169	44	relevance	relevance	NN
cord-010027-r0tl01kq	169	45	to	to	IN
cord-010027-r0tl01kq	169	46	the	the	DT
cord-010027-r0tl01kq	169	47	case	case	NN
cord-010027-r0tl01kq	169	48	under	under	IN
cord-010027-r0tl01kq	169	49	study	study	NN
cord-010027-r0tl01kq	169	50	.	.	.
cord-010027-r0tl01kq	170	1	Most	Most	JJS
cord-010027-r0tl01kq	170	2	melanomas	melanoma	NNS
cord-010027-r0tl01kq	170	3	are	be	VBP
cord-010027-r0tl01kq	170	4	fairly	fairly	RB
cord-010027-r0tl01kq	170	5	easy	easy	JJ
cord-010027-r0tl01kq	170	6	to	to	TO
cord-010027-r0tl01kq	170	7	diagnose	diagnose	VB
cord-010027-r0tl01kq	170	8	on	on	IN
cord-010027-r0tl01kq	170	9	histological	histological	JJ
cord-010027-r0tl01kq	170	10	grounds	ground	NNS
cord-010027-r0tl01kq	170	11	.	.	.
cord-010027-r0tl01kq	171	1	However	however	RB
cord-010027-r0tl01kq	171	2	,	,	,
cord-010027-r0tl01kq	171	3	melanoma	melanoma	NN
cord-010027-r0tl01kq	171	4	is	be	VBZ
cord-010027-r0tl01kq	171	5	a	a	DT
cord-010027-r0tl01kq	171	6	tumour	tumour	NN
cord-010027-r0tl01kq	171	7	that	that	WDT
cord-010027-r0tl01kq	171	8	can	can	MD
cord-010027-r0tl01kq	171	9	histologically	histologically	RB
cord-010027-r0tl01kq	171	10	mimic	mimic	VB
cord-010027-r0tl01kq	171	11	almost	almost	RB
cord-010027-r0tl01kq	171	12	any	any	DT
cord-010027-r0tl01kq	171	13	other	other	JJ
cord-010027-r0tl01kq	171	14	tumour	tumour	NN
cord-010027-r0tl01kq	171	15	including	include	VBG
cord-010027-r0tl01kq	171	16	epithelial	epithelial	JJ
cord-010027-r0tl01kq	171	17	and	and	CC
cord-010027-r0tl01kq	171	18	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	171	19	neoplasms	neoplasm	NNS
cord-010027-r0tl01kq	171	20	.	.	.
cord-010027-r0tl01kq	172	1	Pathologists	pathologist	NNS
cord-010027-r0tl01kq	172	2	need	need	VBP
cord-010027-r0tl01kq	172	3	to	to	TO
cord-010027-r0tl01kq	172	4	familiarize	familiarize	VB
cord-010027-r0tl01kq	172	5	with	with	IN
cord-010027-r0tl01kq	172	6	the	the	DT
cord-010027-r0tl01kq	172	7	wide	wide	JJ
cord-010027-r0tl01kq	172	8	histological	histological	JJ
cord-010027-r0tl01kq	172	9	appearances	appearance	NNS
cord-010027-r0tl01kq	172	10	of	of	IN
cord-010027-r0tl01kq	172	11	melanoma	melanoma	NN
cord-010027-r0tl01kq	172	12	to	to	TO
cord-010027-r0tl01kq	172	13	avoid	avoid	VB
cord-010027-r0tl01kq	172	14	serious	serious	JJ
cord-010027-r0tl01kq	172	15	misdiagnoses	misdiagnose	NNS
cord-010027-r0tl01kq	172	16	.	.	.
cord-010027-r0tl01kq	173	1	Of	of	IN
cord-010027-r0tl01kq	173	2	crucial	crucial	JJ
cord-010027-r0tl01kq	173	3	importance	importance	NN
cord-010027-r0tl01kq	173	4	is	be	VBZ
cord-010027-r0tl01kq	173	5	the	the	DT
cord-010027-r0tl01kq	173	6	knowledge	knowledge	NN
cord-010027-r0tl01kq	173	7	that	that	WDT
cord-010027-r0tl01kq	173	8	a	a	DT
cord-010027-r0tl01kq	173	9	number	number	NN
cord-010027-r0tl01kq	173	10	of	of	IN
cord-010027-r0tl01kq	173	11	melanomas	melanoma	NNS
cord-010027-r0tl01kq	173	12	can	can	MD
cord-010027-r0tl01kq	173	13	closely	closely	RB
cord-010027-r0tl01kq	173	14	mimic	mimic	VB
cord-010027-r0tl01kq	173	15	benign	benign	JJ
cord-010027-r0tl01kq	173	16	naevi	naevus	NNS
cord-010027-r0tl01kq	173	17	.	.	.
cord-010027-r0tl01kq	174	1	Some	some	DT
cord-010027-r0tl01kq	174	2	variants	variant	NNS
cord-010027-r0tl01kq	174	3	of	of	IN
cord-010027-r0tl01kq	174	4	melanoma	melanoma	NN
cord-010027-r0tl01kq	174	5	represent	represent	VBP
cord-010027-r0tl01kq	174	6	distinctive	distinctive	JJ
cord-010027-r0tl01kq	174	7	clinicopathological	clinicopathological	JJ
cord-010027-r0tl01kq	174	8	entities	entity	NNS
cord-010027-r0tl01kq	174	9	and	and	CC
cord-010027-r0tl01kq	174	10	these	these	DT
cord-010027-r0tl01kq	174	11	include	include	VBP
cord-010027-r0tl01kq	174	12	desmoplastic	desmoplastic	JJ
cord-010027-r0tl01kq	174	13	melanoma	melanoma	NN
cord-010027-r0tl01kq	174	14	,	,	,
cord-010027-r0tl01kq	174	15	"	"	``
cord-010027-r0tl01kq	174	16	malignant	malignant	JJ
cord-010027-r0tl01kq	174	17	"	"	''
cord-010027-r0tl01kq	174	18	blue	blue	JJ
cord-010027-r0tl01kq	174	19	naevus	naevus	NN
cord-010027-r0tl01kq	174	20	,	,	,
cord-010027-r0tl01kq	174	21	pigment	pigment	NN
cord-010027-r0tl01kq	174	22	synthethizing	synthethizing	NN
cord-010027-r0tl01kq	174	23	melanoma	melanoma	NN
cord-010027-r0tl01kq	174	24	,	,	,
cord-010027-r0tl01kq	174	25	naevoid	naevoid	JJ
cord-010027-r0tl01kq	174	26	melanoma	melanoma	NN
cord-010027-r0tl01kq	174	27	,	,	,
cord-010027-r0tl01kq	174	28	spitzoid	spitzoid	FW
cord-010027-r0tl01kq	174	29	melanoma	melanoma	NN
cord-010027-r0tl01kq	174	30	and	and	CC
cord-010027-r0tl01kq	174	31	epidermotropic	epidermotropic	NNP
cord-010027-r0tl01kq	174	32	metastatic	metastatic	JJ
cord-010027-r0tl01kq	174	33	melanoma	melanoma	NN
cord-010027-r0tl01kq	174	34	.	.	.
cord-010027-r0tl01kq	175	1	Tumoral	Tumoral	NNP
cord-010027-r0tl01kq	175	2	melanosis	melanosis	NNP
cord-010027-r0tl01kq	175	3	refers	refer	VBZ
cord-010027-r0tl01kq	175	4	to	to	TO
cord-010027-r0tl01kq	175	5	complete	complete	VB
cord-010027-r0tl01kq	175	6	regression	regression	NN
cord-010027-r0tl01kq	175	7	of	of	IN
cord-010027-r0tl01kq	175	8	a	a	DT
cord-010027-r0tl01kq	175	9	melanoma	melanoma	NN
cord-010027-r0tl01kq	175	10	,	,	,
cord-010027-r0tl01kq	175	11	a	a	DT
cord-010027-r0tl01kq	175	12	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	175	13	that	that	IN
cord-010027-r0tl01kq	175	14	it	-PRON-	PRP
cord-010027-r0tl01kq	175	15	is	be	VBZ
cord-010027-r0tl01kq	175	16	often	often	RB
cord-010027-r0tl01kq	175	17	missed	miss	VBN
cord-010027-r0tl01kq	175	18	because	because	IN
cord-010027-r0tl01kq	175	19	of	of	IN
cord-010027-r0tl01kq	175	20	the	the	DT
cord-010027-r0tl01kq	175	21	absence	absence	NN
cord-010027-r0tl01kq	175	22	of	of	IN
cord-010027-r0tl01kq	175	23	tumour	tumour	NN
cord-010027-r0tl01kq	175	24	cells	cell	NNS
cord-010027-r0tl01kq	175	25	within	within	IN
cord-010027-r0tl01kq	175	26	the	the	DT
cord-010027-r0tl01kq	175	27	regressed	regressed	JJ
cord-010027-r0tl01kq	175	28	area	area	NN
cord-010027-r0tl01kq	175	29	.	.	.
cord-010027-r0tl01kq	176	1	A	a	DT
cord-010027-r0tl01kq	176	2	small	small	JJ
cord-010027-r0tl01kq	176	3	percentage	percentage	NN
cord-010027-r0tl01kq	176	4	of	of	IN
cord-010027-r0tl01kq	176	5	melanomas	melanomas	JJR
cord-010027-r0tl01kq	176	6	display	display	VBP
cord-010027-r0tl01kq	176	7	focal	focal	JJ
cord-010027-r0tl01kq	176	8	or	or	CC
cord-010027-r0tl01kq	176	9	extensive	extensive	JJ
cord-010027-r0tl01kq	176	10	histological	histological	JJ
cord-010027-r0tl01kq	176	11	changes	change	NNS
cord-010027-r0tl01kq	176	12	that	that	WDT
cord-010027-r0tl01kq	176	13	closely	closely	RB
cord-010027-r0tl01kq	176	14	mimic	mimic	VBP
cord-010027-r0tl01kq	176	15	other	other	JJ
cord-010027-r0tl01kq	176	16	neoplasms	neoplasm	NNS
cord-010027-r0tl01kq	176	17	and	and	CC
cord-010027-r0tl01kq	176	18	often	often	RB
cord-010027-r0tl01kq	176	19	a	a	DT
cord-010027-r0tl01kq	176	20	combination	combination	NN
cord-010027-r0tl01kq	176	21	of	of	IN
cord-010027-r0tl01kq	176	22	histological	histological	JJ
cord-010027-r0tl01kq	176	23	features	feature	NNS
cord-010027-r0tl01kq	176	24	with	with	IN
cord-010027-r0tl01kq	176	25	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	176	26	is	be	VBZ
cord-010027-r0tl01kq	176	27	necessary	necessary	JJ
cord-010027-r0tl01kq	176	28	to	to	TO
cord-010027-r0tl01kq	176	29	arrive	arrive	VB
cord-010027-r0tl01kq	176	30	to	to	IN
cord-010027-r0tl01kq	176	31	the	the	DT
cord-010027-r0tl01kq	176	32	correct	correct	JJ
cord-010027-r0tl01kq	176	33	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	176	34	.	.	.
cord-010027-r0tl01kq	177	1	Microscopic	microscopic	JJ
cord-010027-r0tl01kq	177	2	variants	variant	NNS
cord-010027-r0tl01kq	177	3	of	of	IN
cord-010027-r0tl01kq	177	4	melanoma	melanoma	NN
cord-010027-r0tl01kq	177	5	include	include	VBP
cord-010027-r0tl01kq	177	6	adenoid	adenoid	NN
cord-010027-r0tl01kq	177	7	(	(	-LRB-
cord-010027-r0tl01kq	177	8	pseudoglandular	pseudoglandular	NNP
cord-010027-r0tl01kq	177	9	)	)	-RRB-
cord-010027-r0tl01kq	177	10	,	,	,
cord-010027-r0tl01kq	177	11	angiotropic	angiotropic	NNP
cord-010027-r0tl01kq	177	12	and	and	CC
cord-010027-r0tl01kq	177	13	angiomatoid	angiomatoid	NNP
cord-010027-r0tl01kq	177	14	,	,	,
cord-010027-r0tl01kq	177	15	signet	signet	NN
cord-010027-r0tl01kq	177	16	ring	ring	NN
cord-010027-r0tl01kq	177	17	cell	cell	NN
cord-010027-r0tl01kq	177	18	,	,	,
cord-010027-r0tl01kq	177	19	balloon	balloon	NN
cord-010027-r0tl01kq	177	20	cell	cell	NN
cord-010027-r0tl01kq	177	21	,	,	,
cord-010027-r0tl01kq	177	22	clear	clear	JJ
cord-010027-r0tl01kq	177	23	cell	cell	NN
cord-010027-r0tl01kq	177	24	,	,	,
cord-010027-r0tl01kq	177	25	rhabdoid	rhabdoid	NN
cord-010027-r0tl01kq	177	26	and	and	CC
cord-010027-r0tl01kq	177	27	follicular	follicular	JJ
cord-010027-r0tl01kq	177	28	(	(	-LRB-
cord-010027-r0tl01kq	177	29	with	with	IN
cord-010027-r0tl01kq	177	30	exclusive	exclusive	JJ
cord-010027-r0tl01kq	177	31	involvement	involvement	NN
cord-010027-r0tl01kq	177	32	of	of	IN
cord-010027-r0tl01kq	177	33	hair	hair	NN
cord-010027-r0tl01kq	177	34	follicles	follicle	NNS
cord-010027-r0tl01kq	177	35	)	)	-RRB-
cord-010027-r0tl01kq	177	36	.	.	.
cord-010027-r0tl01kq	178	1	Some	some	DT
cord-010027-r0tl01kq	178	2	melanomas	melanoma	NNS
cord-010027-r0tl01kq	178	3	display	display	VBP
cord-010027-r0tl01kq	178	4	heterologous	heterologous	JJ
cord-010027-r0tl01kq	178	5	differentiation	differentiation	NN
cord-010027-r0tl01kq	178	6	also	also	RB
cord-010027-r0tl01kq	178	7	known	know	VBN
cord-010027-r0tl01kq	178	8	as	as	IN
cord-010027-r0tl01kq	178	9	transdifferentiation	transdifferentiation	NN
cord-010027-r0tl01kq	178	10	.	.	.
cord-010027-r0tl01kq	179	1	The	the	DT
cord-010027-r0tl01kq	179	2	latter	latter	JJ
cord-010027-r0tl01kq	179	3	should	should	MD
cord-010027-r0tl01kq	179	4	not	not	RB
cord-010027-r0tl01kq	179	5	be	be	VB
cord-010027-r0tl01kq	179	6	confused	confuse	VBN
cord-010027-r0tl01kq	179	7	with	with	IN
cord-010027-r0tl01kq	179	8	the	the	DT
cord-010027-r0tl01kq	179	9	so	so	RB
cord-010027-r0tl01kq	179	10	-	-	HYPH
cord-010027-r0tl01kq	179	11	called	call	VBN
cord-010027-r0tl01kq	179	12	collision	collision	NN
cord-010027-r0tl01kq	179	13	tumour	tumour	NN
cord-010027-r0tl01kq	179	14	in	in	IN
cord-010027-r0tl01kq	179	15	which	which	WDT
cord-010027-r0tl01kq	179	16	a	a	DT
cord-010027-r0tl01kq	179	17	melanoma	melanoma	NN
cord-010027-r0tl01kq	179	18	co	co	NN
cord-010027-r0tl01kq	179	19	-	-	NN
cord-010027-r0tl01kq	179	20	exists	exist	VBZ
cord-010027-r0tl01kq	179	21	with	with	IN
cord-010027-r0tl01kq	179	22	a	a	DT
cord-010027-r0tl01kq	179	23	neoplasm	neoplasm	NN
cord-010027-r0tl01kq	179	24	of	of	IN
cord-010027-r0tl01kq	179	25	different	different	JJ
cord-010027-r0tl01kq	179	26	lineage	lineage	NN
cord-010027-r0tl01kq	179	27	.	.	.
cord-010027-r0tl01kq	180	1	A	a	DT
cord-010027-r0tl01kq	180	2	wide	wide	JJ
cord-010027-r0tl01kq	180	3	variety	variety	NN
cord-010027-r0tl01kq	180	4	of	of	IN
cord-010027-r0tl01kq	180	5	heterologous	heterologous	JJ
cord-010027-r0tl01kq	180	6	differentiation	differentiation	NN
cord-010027-r0tl01kq	180	7	has	have	VBZ
cord-010027-r0tl01kq	180	8	been	be	VBN
cord-010027-r0tl01kq	180	9	described	describe	VBN
cord-010027-r0tl01kq	180	10	in	in	IN
cord-010027-r0tl01kq	180	11	melanoma	melanoma	NN
cord-010027-r0tl01kq	180	12	including	include	VBG
cord-010027-r0tl01kq	180	13	osteosarcomatous	osteosarcomatous	JJ
cord-010027-r0tl01kq	180	14	and	and	CC
cord-010027-r0tl01kq	180	15	chondrosarcomatous	chondrosarcomatous	NNP
cord-010027-r0tl01kq	180	16	(	(	-LRB-
cord-010027-r0tl01kq	180	17	mainly	mainly	RB
cord-010027-r0tl01kq	180	18	seen	see	VBN
cord-010027-r0tl01kq	180	19	in	in	IN
cord-010027-r0tl01kq	180	20	acral	acral	JJ
cord-010027-r0tl01kq	180	21	melanomas	melanoma	NNS
cord-010027-r0tl01kq	180	22	)	)	-RRB-
cord-010027-r0tl01kq	180	23	,	,	,
cord-010027-r0tl01kq	180	24	meiomysarcomatous	meiomysarcomatous	JJ
cord-010027-r0tl01kq	180	25	,	,	,
cord-010027-r0tl01kq	180	26	rhabdomyosarcomatous	rhabdomyosarcomatous	JJ
cord-010027-r0tl01kq	180	27	,	,	,
cord-010027-r0tl01kq	180	28	neuroendocrine	neuroendocrine	JJ
cord-010027-r0tl01kq	180	29	,	,	,
cord-010027-r0tl01kq	180	30	ganglioneuromatous	ganglioneuromatous	JJ
cord-010027-r0tl01kq	180	31	and	and	CC
cord-010027-r0tl01kq	180	32	even	even	RB
cord-010027-r0tl01kq	180	33	epithelial	epithelial	JJ
cord-010027-r0tl01kq	180	34	.	.	.
cord-010027-r0tl01kq	181	1	Except	except	IN
cord-010027-r0tl01kq	181	2	for	for	IN
cord-010027-r0tl01kq	181	3	desmoplastic	desmoplastic	JJ
cord-010027-r0tl01kq	181	4	and	and	CC
cord-010027-r0tl01kq	181	5	pigment	pigment	NN
cord-010027-r0tl01kq	181	6	synthetizing	synthetize	VBG
cord-010027-r0tl01kq	181	7	melanoma	melanoma	NN
cord-010027-r0tl01kq	181	8	,	,	,
cord-010027-r0tl01kq	181	9	all	all	DT
cord-010027-r0tl01kq	181	10	other	other	JJ
cord-010027-r0tl01kq	181	11	variants	variant	NNS
cord-010027-r0tl01kq	181	12	of	of	IN
cord-010027-r0tl01kq	181	13	the	the	DT
cord-010027-r0tl01kq	181	14	tumour	tumour	NN
cord-010027-r0tl01kq	181	15	have	have	VBP
cord-010027-r0tl01kq	181	16	the	the	DT
cord-010027-r0tl01kq	181	17	same	same	JJ
cord-010027-r0tl01kq	181	18	behaviour	behaviour	NN
cord-010027-r0tl01kq	181	19	as	as	IN
cord-010027-r0tl01kq	181	20	ordinary	ordinary	JJ
cord-010027-r0tl01kq	181	21	melanomas	melanoma	NNS
cord-010027-r0tl01kq	181	22	.	.	.
cord-010027-r0tl01kq	182	1	Melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	182	2	tumours	tumour	NNS
cord-010027-r0tl01kq	182	3	with	with	IN
cord-010027-r0tl01kq	182	4	Spitzoid	Spitzoid	NNP
cord-010027-r0tl01kq	182	5	features	feature	VBZ
cord-010027-r0tl01kq	182	6	represent	represent	VBP
cord-010027-r0tl01kq	182	7	one	one	CD
cord-010027-r0tl01kq	182	8	of	of	IN
cord-010027-r0tl01kq	182	9	the	the	DT
cord-010027-r0tl01kq	182	10	most	most	RBS
cord-010027-r0tl01kq	182	11	challenging	challenging	JJ
cord-010027-r0tl01kq	182	12	and	and	CC
cord-010027-r0tl01kq	182	13	controversial	controversial	JJ
cord-010027-r0tl01kq	182	14	areas	area	NNS
cord-010027-r0tl01kq	182	15	in	in	IN
cord-010027-r0tl01kq	182	16	Dermatopathology	Dermatopathology	NNP
cord-010027-r0tl01kq	182	17	.	.	.
cord-010027-r0tl01kq	183	1	What	what	WP
cord-010027-r0tl01kq	183	2	is	be	VBZ
cord-010027-r0tl01kq	183	3	currently	currently	RB
cord-010027-r0tl01kq	183	4	known	know	VBN
cord-010027-r0tl01kq	183	5	as	as	IN
cord-010027-r0tl01kq	183	6	Spitz	Spitz	NNP
cord-010027-r0tl01kq	183	7	naevus	naevus	NN
cord-010027-r0tl01kq	183	8	was	be	VBD
cord-010027-r0tl01kq	183	9	initially	initially	RB
cord-010027-r0tl01kq	183	10	reported	report	VBN
cord-010027-r0tl01kq	183	11	as	as	IN
cord-010027-r0tl01kq	183	12	"	"	``
cord-010027-r0tl01kq	183	13	juvenile	juvenile	JJ
cord-010027-r0tl01kq	183	14	melanoma	melanoma	NN
cord-010027-r0tl01kq	183	15	"	"	''
cord-010027-r0tl01kq	183	16	by	by	IN
cord-010027-r0tl01kq	183	17	Sophie	Sophie	NNP
cord-010027-r0tl01kq	183	18	Spitz	Spitz	NNP
cord-010027-r0tl01kq	183	19	on	on	IN
cord-010027-r0tl01kq	183	20	1948	1948	CD
cord-010027-r0tl01kq	183	21	.	.	.
cord-010027-r0tl01kq	184	1	She	-PRON-	PRP
cord-010027-r0tl01kq	184	2	recognized	recognize	VBD
cord-010027-r0tl01kq	184	3	the	the	DT
cord-010027-r0tl01kq	184	4	relatively	relatively	RB
cord-010027-r0tl01kq	184	5	indolent	indolent	JJ
cord-010027-r0tl01kq	184	6	but	but	CC
cord-010027-r0tl01kq	184	7	somewhat	somewhat	RB
cord-010027-r0tl01kq	184	8	unpredictable	unpredictable	JJ
cord-010027-r0tl01kq	184	9	behaviour	behaviour	NN
cord-010027-r0tl01kq	184	10	of	of	IN
cord-010027-r0tl01kq	184	11	these	these	DT
cord-010027-r0tl01kq	184	12	distinctive	distinctive	JJ
cord-010027-r0tl01kq	184	13	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	184	14	lesions	lesion	NNS
cord-010027-r0tl01kq	184	15	that	that	WDT
cord-010027-r0tl01kq	184	16	are	be	VBP
cord-010027-r0tl01kq	184	17	particularly	particularly	RB
cord-010027-r0tl01kq	184	18	common	common	JJ
cord-010027-r0tl01kq	184	19	in	in	IN
cord-010027-r0tl01kq	184	20	young	young	JJ
cord-010027-r0tl01kq	184	21	children	child	NNS
cord-010027-r0tl01kq	184	22	.	.	.
cord-010027-r0tl01kq	185	1	Over	over	IN
cord-010027-r0tl01kq	185	2	the	the	DT
cord-010027-r0tl01kq	185	3	years	year	NNS
cord-010027-r0tl01kq	185	4	,	,	,
cord-010027-r0tl01kq	185	5	the	the	DT
cord-010027-r0tl01kq	185	6	histological	histological	JJ
cord-010027-r0tl01kq	185	7	spectrum	spectrum	NN
cord-010027-r0tl01kq	185	8	of	of	IN
cord-010027-r0tl01kq	185	9	these	these	DT
cord-010027-r0tl01kq	185	10	tumours	tumour	NNS
cord-010027-r0tl01kq	185	11	was	be	VBD
cord-010027-r0tl01kq	185	12	expanded	expand	VBN
cord-010027-r0tl01kq	185	13	,	,	,
cord-010027-r0tl01kq	185	14	and	and	CC
cord-010027-r0tl01kq	185	15	it	-PRON-	PRP
cord-010027-r0tl01kq	185	16	has	have	VBZ
cord-010027-r0tl01kq	185	17	become	become	VBN
cord-010027-r0tl01kq	185	18	clear	clear	JJ
cord-010027-r0tl01kq	185	19	that	that	IN
cord-010027-r0tl01kq	185	20	classical	classical	JJ
cord-010027-r0tl01kq	185	21	Spitz	Spitz	NNP
cord-010027-r0tl01kq	185	22	naevi	naevus	NNS
cord-010027-r0tl01kq	185	23	follow	follow	VBP
cord-010027-r0tl01kq	185	24	an	an	DT
cord-010027-r0tl01kq	185	25	entirely	entirely	RB
cord-010027-r0tl01kq	185	26	indolent	indolent	JJ
cord-010027-r0tl01kq	185	27	disease	disease	NN
cord-010027-r0tl01kq	185	28	course	course	NN
cord-010027-r0tl01kq	185	29	.	.	.
cord-010027-r0tl01kq	186	1	The	the	DT
cord-010027-r0tl01kq	186	2	prognosis	prognosis	NN
cord-010027-r0tl01kq	186	3	of	of	IN
cord-010027-r0tl01kq	186	4	tumours	tumour	NNS
cord-010027-r0tl01kq	186	5	with	with	IN
cord-010027-r0tl01kq	186	6	atypical	atypical	JJ
cord-010027-r0tl01kq	186	7	histological	histological	JJ
cord-010027-r0tl01kq	186	8	features	feature	NNS
cord-010027-r0tl01kq	186	9	remains	remain	VBZ
cord-010027-r0tl01kq	186	10	somewhat	somewhat	RB
cord-010027-r0tl01kq	186	11	unpredictable	unpredictable	JJ
cord-010027-r0tl01kq	186	12	.	.	.
cord-010027-r0tl01kq	187	1	This	this	DT
cord-010027-r0tl01kq	187	2	presentation	presentation	NN
cord-010027-r0tl01kq	187	3	will	will	MD
cord-010027-r0tl01kq	187	4	give	give	VB
cord-010027-r0tl01kq	187	5	an	an	DT
cord-010027-r0tl01kq	187	6	overview	overview	NN
cord-010027-r0tl01kq	187	7	of	of	IN
cord-010027-r0tl01kq	187	8	the	the	DT
cord-010027-r0tl01kq	187	9	morphological	morphological	JJ
cord-010027-r0tl01kq	187	10	spectrum	spectrum	NN
cord-010027-r0tl01kq	187	11	of	of	IN
cord-010027-r0tl01kq	187	12	Spitzoid	Spitzoid	NNP
cord-010027-r0tl01kq	187	13	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	187	14	tumours	tumour	NNS
cord-010027-r0tl01kq	187	15	,	,	,
cord-010027-r0tl01kq	187	16	their	-PRON-	PRP$
cord-010027-r0tl01kq	187	17	behaviour	behaviour	NN
cord-010027-r0tl01kq	187	18	and	and	CC
cord-010027-r0tl01kq	187	19	recent	recent	JJ
cord-010027-r0tl01kq	187	20	advances	advance	NNS
cord-010027-r0tl01kq	187	21	of	of	IN
cord-010027-r0tl01kq	187	22	their	-PRON-	PRP$
cord-010027-r0tl01kq	187	23	molecular	molecular	JJ
cord-010027-r0tl01kq	187	24	characteristics	characteristic	NNS
cord-010027-r0tl01kq	187	25	.	.	.
cord-010027-r0tl01kq	188	1	Optimisation	optimisation	NN
cord-010027-r0tl01kq	188	2	is	be	VBZ
cord-010027-r0tl01kq	188	3	a	a	DT
cord-010027-r0tl01kq	188	4	core	core	NN
cord-010027-r0tl01kq	188	5	tenet	tenet	NN
cord-010027-r0tl01kq	188	6	in	in	IN
cord-010027-r0tl01kq	188	7	radiography	radiography	NN
cord-010027-r0tl01kq	188	8	and	and	CC
cord-010027-r0tl01kq	188	9	involves	involve	VBZ
cord-010027-r0tl01kq	188	10	the	the	DT
cord-010027-r0tl01kq	188	11	radiographer	radiographer	NN
cord-010027-r0tl01kq	188	12	ensuring	ensure	VBG
cord-010027-r0tl01kq	188	13	that	that	IN
cord-010027-r0tl01kq	188	14	images	image	NNS
cord-010027-r0tl01kq	188	15	of	of	IN
cord-010027-r0tl01kq	188	16	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	188	17	quality	quality	NN
cord-010027-r0tl01kq	188	18	are	be	VBP
cord-010027-r0tl01kq	188	19	produced	produce	VBN
cord-010027-r0tl01kq	188	20	with	with	IN
cord-010027-r0tl01kq	188	21	minimum	minimum	JJ
cord-010027-r0tl01kq	188	22	radiation	radiation	NN
cord-010027-r0tl01kq	188	23	dose	dose	NN
cord-010027-r0tl01kq	188	24	burden	burden	NN
cord-010027-r0tl01kq	188	25	to	to	IN
cord-010027-r0tl01kq	188	26	patient	patient	NN
cord-010027-r0tl01kq	188	27	and	and	CC
cord-010027-r0tl01kq	188	28	staff	staff	NN
cord-010027-r0tl01kq	188	29	[	[	-LRB-
cord-010027-r0tl01kq	188	30	1	1	CD
cord-010027-r0tl01kq	188	31	,	,	,
cord-010027-r0tl01kq	188	32	2	2	CD
cord-010027-r0tl01kq	188	33	]	]	-RRB-
cord-010027-r0tl01kq	188	34	.	.	.
cord-010027-r0tl01kq	189	1	In	in	IN
cord-010027-r0tl01kq	189	2	paediatric	paediatric	JJ
cord-010027-r0tl01kq	189	3	practice	practice	NN
cord-010027-r0tl01kq	189	4	this	this	DT
cord-010027-r0tl01kq	189	5	is	be	VBZ
cord-010027-r0tl01kq	189	6	particularly	particularly	RB
cord-010027-r0tl01kq	189	7	important	important	JJ
cord-010027-r0tl01kq	189	8	due	due	IN
cord-010027-r0tl01kq	189	9	to	to	IN
cord-010027-r0tl01kq	189	10	the	the	DT
cord-010027-r0tl01kq	189	11	more	more	RBR
cord-010027-r0tl01kq	189	12	radiosensitive	radiosensitive	JJ
cord-010027-r0tl01kq	189	13	nature	nature	NN
cord-010027-r0tl01kq	189	14	of	of	IN
cord-010027-r0tl01kq	189	15	the	the	DT
cord-010027-r0tl01kq	189	16	child	child	NN
cord-010027-r0tl01kq	189	17	[	[	-LRB-
cord-010027-r0tl01kq	189	18	1	1	CD
cord-010027-r0tl01kq	189	19	]	]	-RRB-
cord-010027-r0tl01kq	189	20	.	.	.
cord-010027-r0tl01kq	190	1	In	in	IN
cord-010027-r0tl01kq	190	2	alignment	alignment	NN
cord-010027-r0tl01kq	190	3	with	with	IN
cord-010027-r0tl01kq	190	4	the	the	DT
cord-010027-r0tl01kq	190	5	ISRRT	ISRRT	NNP
cord-010027-r0tl01kq	190	6	2013	2013	CD
cord-010027-r0tl01kq	190	7	World	World	NNP
cord-010027-r0tl01kq	190	8	Radiography	Radiography	NNP
cord-010027-r0tl01kq	190	9	Day	Day	NNP
cord-010027-r0tl01kq	190	10	theme	theme	NN
cord-010027-r0tl01kq	190	11	'	'	''
cord-010027-r0tl01kq	190	12	Radiographers	Radiographers	NNP
cord-010027-r0tl01kq	190	13	Optimise	Optimise	NNP
cord-010027-r0tl01kq	190	14	Dose	Dose	NNP
cord-010027-r0tl01kq	190	15	'	'	''
cord-010027-r0tl01kq	190	16	,	,	,
cord-010027-r0tl01kq	190	17	radiography	radiography	NN
cord-010027-r0tl01kq	190	18	students	student	NNS
cord-010027-r0tl01kq	190	19	in	in	IN
cord-010027-r0tl01kq	190	20	an	an	DT
cord-010027-r0tl01kq	190	21	institution	institution	NN
cord-010027-r0tl01kq	190	22	submitted	submit	VBD
cord-010027-r0tl01kq	190	23	clinical	clinical	JJ
cord-010027-r0tl01kq	190	24	case	case	NN
cord-010027-r0tl01kq	190	25	study	study	NN
cord-010027-r0tl01kq	190	26	coursework	coursework	NN
cord-010027-r0tl01kq	190	27	that	that	WDT
cord-010027-r0tl01kq	190	28	focused	focus	VBD
cord-010027-r0tl01kq	190	29	on	on	IN
cord-010027-r0tl01kq	190	30	paediatric	paediatric	JJ
cord-010027-r0tl01kq	190	31	radiation	radiation	NN
cord-010027-r0tl01kq	190	32	dose	dose	NN
cord-010027-r0tl01kq	190	33	optimisation	optimisation	NN
cord-010027-r0tl01kq	190	34	.	.	.
cord-010027-r0tl01kq	191	1	The	the	DT
cord-010027-r0tl01kq	191	2	purpose	purpose	NN
cord-010027-r0tl01kq	191	3	of	of	IN
cord-010027-r0tl01kq	191	4	the	the	DT
cord-010027-r0tl01kq	191	5	current	current	JJ
cord-010027-r0tl01kq	191	6	study	study	NN
cord-010027-r0tl01kq	191	7	was	be	VBD
cord-010027-r0tl01kq	191	8	to	to	TO
cord-010027-r0tl01kq	191	9	analyse	analyse	VB
cord-010027-r0tl01kq	191	10	these	these	DT
cord-010027-r0tl01kq	191	11	case	case	NN
cord-010027-r0tl01kq	191	12	studies	study	NNS
cord-010027-r0tl01kq	191	13	as	as	IN
cord-010027-r0tl01kq	191	14	examples	example	NNS
cord-010027-r0tl01kq	191	15	of	of	IN
cord-010027-r0tl01kq	191	16	prevailing	prevail	VBG
cord-010027-r0tl01kq	191	17	radiographic	radiographic	JJ
cord-010027-r0tl01kq	191	18	practice	practice	NN
cord-010027-r0tl01kq	191	19	and	and	CC
cord-010027-r0tl01kq	191	20	to	to	TO
cord-010027-r0tl01kq	191	21	compare	compare	VB
cord-010027-r0tl01kq	191	22	students	student	NNS
cord-010027-r0tl01kq	191	23	'	'	POS
cord-010027-r0tl01kq	191	24	perception	perception	NN
cord-010027-r0tl01kq	191	25	of	of	IN
cord-010027-r0tl01kq	191	26	optimisation	optimisation	NN
cord-010027-r0tl01kq	191	27	with	with	IN
cord-010027-r0tl01kq	191	28	the	the	DT
cord-010027-r0tl01kq	191	29	evidence	evidence	NN
cord-010027-r0tl01kq	191	30	within	within	IN
cord-010027-r0tl01kq	191	31	each	each	DT
cord-010027-r0tl01kq	191	32	case	case	NN
cord-010027-r0tl01kq	191	33	.	.	.
cord-010027-r0tl01kq	192	1	The	the	DT
cord-010027-r0tl01kq	192	2	evidence	evidence	NN
cord-010027-r0tl01kq	192	3	of	of	IN
cord-010027-r0tl01kq	192	4	optimisation	optimisation	NN
cord-010027-r0tl01kq	192	5	was	be	VBD
cord-010027-r0tl01kq	192	6	established	establish	VBN
cord-010027-r0tl01kq	192	7	through	through	IN
cord-010027-r0tl01kq	192	8	independent	independent	JJ
cord-010027-r0tl01kq	192	9	and	and	CC
cord-010027-r0tl01kq	192	10	objective	objective	JJ
cord-010027-r0tl01kq	192	11	image	image	NN
cord-010027-r0tl01kq	192	12	analysis	analysis	NN
cord-010027-r0tl01kq	192	13	along	along	IN
cord-010027-r0tl01kq	192	14	with	with	IN
cord-010027-r0tl01kq	192	15	thematic	thematic	JJ
cord-010027-r0tl01kq	192	16	analysis	analysis	NN
cord-010027-r0tl01kq	192	17	of	of	IN
cord-010027-r0tl01kq	192	18	the	the	DT
cord-010027-r0tl01kq	192	19	case	case	NN
cord-010027-r0tl01kq	192	20	commentaries	commentary	NNS
cord-010027-r0tl01kq	192	21	.	.	.
cord-010027-r0tl01kq	193	1	The	the	DT
cord-010027-r0tl01kq	193	2	case	case	NN
cord-010027-r0tl01kq	193	3	study	study	NN
cord-010027-r0tl01kq	193	4	evidence	evidence	NN
cord-010027-r0tl01kq	193	5	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	193	6	that	that	IN
cord-010027-r0tl01kq	193	7	optimised	optimise	VBN
cord-010027-r0tl01kq	193	8	techniques	technique	NNS
cord-010027-r0tl01kq	193	9	were	be	VBD
cord-010027-r0tl01kq	193	10	generally	generally	RB
cord-010027-r0tl01kq	193	11	well	well	RB
cord-010027-r0tl01kq	193	12	implemented	implement	VBN
cord-010027-r0tl01kq	193	13	.	.	.
cord-010027-r0tl01kq	194	1	The	the	DT
cord-010027-r0tl01kq	194	2	exception	exception	NN
cord-010027-r0tl01kq	194	3	was	be	VBD
cord-010027-r0tl01kq	194	4	collimation	collimation	NN
cord-010027-r0tl01kq	194	5	,	,	,
cord-010027-r0tl01kq	194	6	which	which	WDT
cord-010027-r0tl01kq	194	7	was	be	VBD
cord-010027-r0tl01kq	194	8	sub	sub	NN
cord-010027-r0tl01kq	194	9	-	-	JJ
cord-010027-r0tl01kq	194	10	optimal	optimal	JJ
cord-010027-r0tl01kq	194	11	in	in	IN
cord-010027-r0tl01kq	194	12	84	84	CD
cord-010027-r0tl01kq	194	13	%	%	NN
cord-010027-r0tl01kq	194	14	(	(	-LRB-
cord-010027-r0tl01kq	194	15	n=31	n=31	NNP
cord-010027-r0tl01kq	194	16	)	)	-RRB-
cord-010027-r0tl01kq	194	17	of	of	IN
cord-010027-r0tl01kq	194	18	the	the	DT
cord-010027-r0tl01kq	194	19	examinations	examination	NNS
cord-010027-r0tl01kq	194	20	,	,	,
cord-010027-r0tl01kq	194	21	and	and	CC
cord-010027-r0tl01kq	194	22	on	on	IN
cord-010027-r0tl01kq	194	23	average	average	JJ
cord-010027-r0tl01kq	194	24	irradiating	irradiate	VBG
cord-010027-r0tl01kq	194	25	an	an	DT
cord-010027-r0tl01kq	194	26	area	area	NN
cord-010027-r0tl01kq	194	27	27	27	CD
cord-010027-r0tl01kq	194	28	%	%	NN
cord-010027-r0tl01kq	194	29	larger	large	JJR
cord-010027-r0tl01kq	194	30	than	than	IN
cord-010027-r0tl01kq	194	31	necessary	necessary	JJ
cord-010027-r0tl01kq	194	32	.	.	.
cord-010027-r0tl01kq	195	1	Students	student	NNS
cord-010027-r0tl01kq	195	2	were	be	VBD
cord-010027-r0tl01kq	195	3	generally	generally	RB
cord-010027-r0tl01kq	195	4	able	able	JJ
cord-010027-r0tl01kq	195	5	to	to	TO
cord-010027-r0tl01kq	195	6	correctly	correctly	RB
cord-010027-r0tl01kq	195	7	identify	identify	VB
cord-010027-r0tl01kq	195	8	techniques	technique	NNS
cord-010027-r0tl01kq	195	9	as	as	IN
cord-010027-r0tl01kq	195	10	optimal	optimal	JJ
cord-010027-r0tl01kq	195	11	or	or	CC
cord-010027-r0tl01kq	195	12	not	not	RB
cord-010027-r0tl01kq	195	13	.	.	.
cord-010027-r0tl01kq	196	1	However	however	RB
cord-010027-r0tl01kq	196	2	,	,	,
cord-010027-r0tl01kq	196	3	when	when	WRB
cord-010027-r0tl01kq	196	4	appraising	appraise	VBG
cord-010027-r0tl01kq	196	5	exposure	exposure	NN
cord-010027-r0tl01kq	196	6	,	,	,
cord-010027-r0tl01kq	196	7	positioning	positioning	NN
cord-010027-r0tl01kq	196	8	and	and	CC
cord-010027-r0tl01kq	196	9	collimation	collimation	NN
cord-010027-r0tl01kq	196	10	,	,	,
cord-010027-r0tl01kq	196	11	between	between	IN
cord-010027-r0tl01kq	196	12	9	9	CD
cord-010027-r0tl01kq	196	13	%	%	NN
cord-010027-r0tl01kq	196	14	and	and	CC
cord-010027-r0tl01kq	196	15	33	33	CD
cord-010027-r0tl01kq	196	16	%	%	NN
cord-010027-r0tl01kq	196	17	of	of	IN
cord-010027-r0tl01kq	196	18	students	student	NNS
cord-010027-r0tl01kq	196	19	were	be	VBD
cord-010027-r0tl01kq	196	20	inaccurate	inaccurate	JJ
cord-010027-r0tl01kq	196	21	in	in	IN
cord-010027-r0tl01kq	196	22	their	-PRON-	PRP$
cord-010027-r0tl01kq	196	23	assessment	assessment	NN
cord-010027-r0tl01kq	196	24	of	of	IN
cord-010027-r0tl01kq	196	25	what	what	WP
cord-010027-r0tl01kq	196	26	is	be	VBZ
cord-010027-r0tl01kq	196	27	optimal	optimal	JJ
cord-010027-r0tl01kq	196	28	.	.	.
cord-010027-r0tl01kq	197	1	Overall	overall	RB
cord-010027-r0tl01kq	197	2	the	the	DT
cord-010027-r0tl01kq	197	3	study	study	NN
cord-010027-r0tl01kq	197	4	reflects	reflect	VBZ
cord-010027-r0tl01kq	197	5	positively	positively	RB
cord-010027-r0tl01kq	197	6	on	on	IN
cord-010027-r0tl01kq	197	7	current	current	JJ
cord-010027-r0tl01kq	197	8	Irish	irish	JJ
cord-010027-r0tl01kq	197	9	paediatric	paediatric	JJ
cord-010027-r0tl01kq	197	10	radiography	radiography	NN
cord-010027-r0tl01kq	197	11	with	with	IN
cord-010027-r0tl01kq	197	12	regard	regard	NN
cord-010027-r0tl01kq	197	13	to	to	IN
cord-010027-r0tl01kq	197	14	dose	dose	NN
cord-010027-r0tl01kq	197	15	optimisation	optimisation	NN
cord-010027-r0tl01kq	197	16	,	,	,
cord-010027-r0tl01kq	197	17	although	although	IN
cord-010027-r0tl01kq	197	18	more	more	RBR
cord-010027-r0tl01kq	197	19	accurate	accurate	JJ
cord-010027-r0tl01kq	197	20	collimation	collimation	NN
cord-010027-r0tl01kq	197	21	needs	need	NNS
cord-010027-r0tl01kq	197	22	to	to	TO
cord-010027-r0tl01kq	197	23	be	be	VB
cord-010027-r0tl01kq	197	24	practised	practise	VBN
cord-010027-r0tl01kq	197	25	.	.	.
cord-010027-r0tl01kq	198	1	Similarly	similarly	RB
cord-010027-r0tl01kq	198	2	student	student	NN
cord-010027-r0tl01kq	198	3	perceptions	perception	NNS
cord-010027-r0tl01kq	198	4	show	show	VBP
cord-010027-r0tl01kq	198	5	good	good	JJ
cord-010027-r0tl01kq	198	6	understanding	understanding	NN
cord-010027-r0tl01kq	198	7	of	of	IN
cord-010027-r0tl01kq	198	8	optimal	optimal	JJ
cord-010027-r0tl01kq	198	9	techniques	technique	NNS
cord-010027-r0tl01kq	198	10	,	,	,
cord-010027-r0tl01kq	198	11	although	although	IN
cord-010027-r0tl01kq	198	12	appreciation	appreciation	NN
cord-010027-r0tl01kq	198	13	of	of	IN
cord-010027-r0tl01kq	198	14	exposure	exposure	NN
cord-010027-r0tl01kq	198	15	,	,	,
cord-010027-r0tl01kq	198	16	positioning	positioning	NN
cord-010027-r0tl01kq	198	17	and	and	CC
cord-010027-r0tl01kq	198	18	collimation	collimation	NN
cord-010027-r0tl01kq	198	19	errors	error	NNS
cord-010027-r0tl01kq	198	20	could	could	MD
cord-010027-r0tl01kq	198	21	be	be	VB
cord-010027-r0tl01kq	198	22	improved	improve	VBN
cord-010027-r0tl01kq	198	23	.	.	.
cord-010027-r0tl01kq	199	1	The	the	DT
cord-010027-r0tl01kq	199	2	aim	aim	NN
cord-010027-r0tl01kq	199	3	of	of	IN
cord-010027-r0tl01kq	199	4	this	this	DT
cord-010027-r0tl01kq	199	5	project	project	NN
cord-010027-r0tl01kq	199	6	was	be	VBD
cord-010027-r0tl01kq	199	7	to	to	TO
cord-010027-r0tl01kq	199	8	design	design	VB
cord-010027-r0tl01kq	199	9	and	and	CC
cord-010027-r0tl01kq	199	10	prototype	prototype	NN
cord-010027-r0tl01kq	199	11	immobilisation	immobilisation	NN
cord-010027-r0tl01kq	199	12	devices	device	NNS
cord-010027-r0tl01kq	199	13	for	for	IN
cord-010027-r0tl01kq	199	14	children	child	NNS
cord-010027-r0tl01kq	199	15	who	who	WP
cord-010027-r0tl01kq	199	16	are	be	VBP
cord-010027-r0tl01kq	199	17	unable	unable	JJ
cord-010027-r0tl01kq	199	18	to	to	TO
cord-010027-r0tl01kq	199	19	independently	independently	RB
cord-010027-r0tl01kq	199	20	maintain	maintain	VB
cord-010027-r0tl01kq	199	21	upright	upright	JJ
cord-010027-r0tl01kq	199	22	sitting	sit	VBG
cord-010027-r0tl01kq	199	23	posture	posture	NN
cord-010027-r0tl01kq	199	24	during	during	IN
cord-010027-r0tl01kq	199	25	radiographic	radiographic	JJ
cord-010027-r0tl01kq	199	26	investigations	investigation	NNS
cord-010027-r0tl01kq	199	27	.	.	.
cord-010027-r0tl01kq	200	1	While	while	IN
cord-010027-r0tl01kq	200	2	current	current	JJ
cord-010027-r0tl01kq	200	3	market	market	NN
cord-010027-r0tl01kq	200	4	devices	device	NNS
cord-010027-r0tl01kq	200	5	exist	exist	VBP
cord-010027-r0tl01kq	200	6	,	,	,
cord-010027-r0tl01kq	200	7	they	-PRON-	PRP
cord-010027-r0tl01kq	200	8	are	be	VBP
cord-010027-r0tl01kq	200	9	seldom	seldom	RB
cord-010027-r0tl01kq	200	10	used	use	VBN
cord-010027-r0tl01kq	200	11	by	by	IN
cord-010027-r0tl01kq	200	12	radiographers	radiographer	NNS
cord-010027-r0tl01kq	200	13	-particularly	-particularly	RB
cord-010027-r0tl01kq	200	14	in	in	IN
cord-010027-r0tl01kq	200	15	Europe	Europe	NNP
cord-010027-r0tl01kq	200	16	as	as	IN
cord-010027-r0tl01kq	200	17	their	-PRON-	PRP$
cord-010027-r0tl01kq	200	18	methods	method	NNS
cord-010027-r0tl01kq	200	19	of	of	IN
cord-010027-r0tl01kq	200	20	restraint	restraint	NN
cord-010027-r0tl01kq	200	21	have	have	VBP
cord-010027-r0tl01kq	200	22	been	be	VBN
cord-010027-r0tl01kq	200	23	deemed	deem	VBN
cord-010027-r0tl01kq	200	24	'	'	``
cord-010027-r0tl01kq	200	25	culturally	culturally	RB
cord-010027-r0tl01kq	200	26	unacceptable	unacceptable	JJ
cord-010027-r0tl01kq	200	27	'	'	''
cord-010027-r0tl01kq	200	28	with	with	IN
cord-010027-r0tl01kq	200	29	some	some	DT
cord-010027-r0tl01kq	200	30	claiming	claim	VBG
cord-010027-r0tl01kq	200	31	that	that	IN
cord-010027-r0tl01kq	200	32	they	-PRON-	PRP
cord-010027-r0tl01kq	200	33	are	be	VBP
cord-010027-r0tl01kq	200	34	in	in	IN
cord-010027-r0tl01kq	200	35	violation	violation	NN
cord-010027-r0tl01kq	200	36	of	of	IN
cord-010027-r0tl01kq	200	37	the	the	DT
cord-010027-r0tl01kq	200	38	human	human	JJ
cord-010027-r0tl01kq	200	39	rights	right	NNS
cord-010027-r0tl01kq	200	40	of	of	IN
cord-010027-r0tl01kq	200	41	the	the	DT
cord-010027-r0tl01kq	200	42	child	child	NN
cord-010027-r0tl01kq	200	43	[	[	-LRB-
cord-010027-r0tl01kq	200	44	1	1	CD
cord-010027-r0tl01kq	200	45	]	]	-RRB-
cord-010027-r0tl01kq	200	46	.	.	.
cord-010027-r0tl01kq	201	1	The	the	DT
cord-010027-r0tl01kq	201	2	design	design	NN
cord-010027-r0tl01kq	201	3	challenge	challenge	NN
cord-010027-r0tl01kq	201	4	was	be	VBD
cord-010027-r0tl01kq	201	5	to	to	TO
cord-010027-r0tl01kq	201	6	create	create	VB
cord-010027-r0tl01kq	201	7	devices	device	NNS
cord-010027-r0tl01kq	201	8	that	that	WDT
cord-010027-r0tl01kq	201	9	were	be	VBD
cord-010027-r0tl01kq	201	10	functional	functional	JJ
cord-010027-r0tl01kq	201	11	(	(	-LRB-
cord-010027-r0tl01kq	201	12	fit	fit	JJ
cord-010027-r0tl01kq	201	13	for	for	IN
cord-010027-r0tl01kq	201	14	purpose	purpose	NN
cord-010027-r0tl01kq	201	15	[	[	-LRB-
cord-010027-r0tl01kq	201	16	2	2	CD
cord-010027-r0tl01kq	201	17	]	]	-RRB-
cord-010027-r0tl01kq	201	18	,	,	,
cord-010027-r0tl01kq	201	19	radio	radio	NN
cord-010027-r0tl01kq	201	20	-	-	HYPH
cord-010027-r0tl01kq	201	21	lucent	lucent	NNP
cord-010027-r0tl01kq	201	22	,	,	,
cord-010027-r0tl01kq	201	23	compliant	compliant	JJ
cord-010027-r0tl01kq	201	24	with	with	IN
cord-010027-r0tl01kq	201	25	infection	infection	NN
cord-010027-r0tl01kq	201	26	control	control	NN
cord-010027-r0tl01kq	201	27	and	and	CC
cord-010027-r0tl01kq	201	28	easy	easy	JJ
cord-010027-r0tl01kq	201	29	to	to	TO
cord-010027-r0tl01kq	201	30	use	use	VB
cord-010027-r0tl01kq	201	31	)	)	-RRB-
cord-010027-r0tl01kq	201	32	while	while	IN
cord-010027-r0tl01kq	201	33	minimising	minimise	VBG
cord-010027-r0tl01kq	201	34	discomfort	discomfort	NN
cord-010027-r0tl01kq	201	35	and	and	CC
cord-010027-r0tl01kq	201	36	intimidation	intimidation	NN
cord-010027-r0tl01kq	201	37	.	.	.
cord-010027-r0tl01kq	202	1	A	a	DT
cord-010027-r0tl01kq	202	2	search	search	NN
cord-010027-r0tl01kq	202	3	of	of	IN
cord-010027-r0tl01kq	202	4	the	the	DT
cord-010027-r0tl01kq	202	5	literature	literature	NN
cord-010027-r0tl01kq	202	6	,	,	,
cord-010027-r0tl01kq	202	7	prior	prior	JJ
cord-010027-r0tl01kq	202	8	art	art	NN
cord-010027-r0tl01kq	202	9	,	,	,
cord-010027-r0tl01kq	202	10	patent	patent	NN
cord-010027-r0tl01kq	202	11	landscape	landscape	NN
cord-010027-r0tl01kq	202	12	and	and	CC
cord-010027-r0tl01kq	202	13	current	current	JJ
cord-010027-r0tl01kq	202	14	market	market	NN
cord-010027-r0tl01kq	202	15	devices	device	NNS
cord-010027-r0tl01kq	202	16	was	be	VBD
cord-010027-r0tl01kq	202	17	performed	perform	VBN
cord-010027-r0tl01kq	202	18	in	in	IN
cord-010027-r0tl01kq	202	19	order	order	NN
cord-010027-r0tl01kq	202	20	to	to	TO
cord-010027-r0tl01kq	202	21	identify	identify	VB
cord-010027-r0tl01kq	202	22	product	product	NN
cord-010027-r0tl01kq	202	23	requirements	requirement	NNS
cord-010027-r0tl01kq	202	24	.	.	.
cord-010027-r0tl01kq	203	1	TRIZ	TRIZ	NNS
cord-010027-r0tl01kq	203	2	methodologies	methodology	NNS
cord-010027-r0tl01kq	203	3	-a	-a	:
cord-010027-r0tl01kq	203	4	problem	problem	NN
cord-010027-r0tl01kq	203	5	solving	solving	NN
cord-010027-r0tl01kq	203	6	,	,	,
cord-010027-r0tl01kq	203	7	analysis	analysis	NN
cord-010027-r0tl01kq	203	8	and	and	CC
cord-010027-r0tl01kq	203	9	forecasting	forecasting	NN
cord-010027-r0tl01kq	203	10	tool	tool	NN
cord-010027-r0tl01kq	203	11	derived	derive	VBN
cord-010027-r0tl01kq	203	12	from	from	IN
cord-010027-r0tl01kq	203	13	the	the	DT
cord-010027-r0tl01kq	203	14	study	study	NN
cord-010027-r0tl01kq	203	15	of	of	IN
cord-010027-r0tl01kq	203	16	patterns	pattern	NNS
cord-010027-r0tl01kq	203	17	of	of	IN
cord-010027-r0tl01kq	203	18	invention	invention	NN
cord-010027-r0tl01kq	203	19	in	in	IN
cord-010027-r0tl01kq	203	20	the	the	DT
cord-010027-r0tl01kq	203	21	global	global	JJ
cord-010027-r0tl01kq	203	22	patent	patent	NN
cord-010027-r0tl01kq	203	23	literature	literature	NN
cord-010027-r0tl01kq	203	24	were	be	VBD
cord-010027-r0tl01kq	203	25	used	use	VBN
cord-010027-r0tl01kq	203	26	to	to	TO
cord-010027-r0tl01kq	203	27	identify	identify	VB
cord-010027-r0tl01kq	203	28	the	the	DT
cord-010027-r0tl01kq	203	29	physical	physical	JJ
cord-010027-r0tl01kq	203	30	contradictions	contradiction	NNS
cord-010027-r0tl01kq	203	31	underlying	underlie	VBG
cord-010027-r0tl01kq	203	32	the	the	DT
cord-010027-r0tl01kq	203	33	design	design	NN
cord-010027-r0tl01kq	203	34	challenge	challenge	NN
cord-010027-r0tl01kq	203	35	and	and	CC
cord-010027-r0tl01kq	203	36	generate	generate	VB
cord-010027-r0tl01kq	203	37	potential	potential	JJ
cord-010027-r0tl01kq	203	38	solutions	solution	NNS
cord-010027-r0tl01kq	203	39	.	.	.
cord-010027-r0tl01kq	204	1	Eight	eight	CD
cord-010027-r0tl01kq	204	2	unique	unique	JJ
cord-010027-r0tl01kq	204	3	concept	concept	NN
cord-010027-r0tl01kq	204	4	designs	design	NNS
cord-010027-r0tl01kq	204	5	were	be	VBD
cord-010027-r0tl01kq	204	6	identified	identify	VBN
cord-010027-r0tl01kq	204	7	from	from	IN
cord-010027-r0tl01kq	204	8	these	these	DT
cord-010027-r0tl01kq	204	9	methods	method	NNS
cord-010027-r0tl01kq	204	10	.	.	.
cord-010027-r0tl01kq	205	1	These	these	DT
cord-010027-r0tl01kq	205	2	were	be	VBD
cord-010027-r0tl01kq	205	3	then	then	RB
cord-010027-r0tl01kq	205	4	evaluated	evaluate	VBN
cord-010027-r0tl01kq	205	5	using	use	VBG
cord-010027-r0tl01kq	205	6	Pugh	Pugh	NNP
cord-010027-r0tl01kq	205	7	Criteria	Criteria	NNP
cord-010027-r0tl01kq	205	8	-a	-a	,
cord-010027-r0tl01kq	205	9	ranking	rank	VBG
cord-010027-r0tl01kq	205	10	system	system	NN
cord-010027-r0tl01kq	205	11	of	of	IN
cord-010027-r0tl01kq	205	12	the	the	DT
cord-010027-r0tl01kq	205	13	relative	relative	JJ
cord-010027-r0tl01kq	205	14	merits	merit	NNS
cord-010027-r0tl01kq	205	15	of	of	IN
cord-010027-r0tl01kq	205	16	each	each	DT
cord-010027-r0tl01kq	205	17	concept	concept	NN
cord-010027-r0tl01kq	205	18	based	base	VBN
cord-010027-r0tl01kq	205	19	on	on	IN
cord-010027-r0tl01kq	205	20	design	design	NN
cord-010027-r0tl01kq	205	21	requirements	requirement	NNS
cord-010027-r0tl01kq	205	22	identified	identify	VBN
cord-010027-r0tl01kq	205	23	.	.	.
cord-010027-r0tl01kq	206	1	Four	four	CD
cord-010027-r0tl01kq	206	2	of	of	IN
cord-010027-r0tl01kq	206	3	the	the	DT
cord-010027-r0tl01kq	206	4	eight	eight	CD
cord-010027-r0tl01kq	206	5	concepts	concept	NNS
cord-010027-r0tl01kq	206	6	were	be	VBD
cord-010027-r0tl01kq	206	7	chosen	choose	VBN
cord-010027-r0tl01kq	206	8	to	to	TO
cord-010027-r0tl01kq	206	9	be	be	VB
cord-010027-r0tl01kq	206	10	prototyped	prototype	VBN
cord-010027-r0tl01kq	206	11	:	:	:
cord-010027-r0tl01kq	206	12	a	a	DT
cord-010027-r0tl01kq	206	13	3-D	3-d	JJ
cord-010027-r0tl01kq	206	14	printed	print	VBN
cord-010027-r0tl01kq	206	15	seat	seat	NN
cord-010027-r0tl01kq	206	16	,	,	,
cord-010027-r0tl01kq	206	17	a	a	DT
cord-010027-r0tl01kq	206	18	swing	swing	NN
cord-010027-r0tl01kq	206	19	based	base	VBN
cord-010027-r0tl01kq	206	20	template	template	NN
cord-010027-r0tl01kq	206	21	,	,	,
cord-010027-r0tl01kq	206	22	an	an	DT
cord-010027-r0tl01kq	206	23	acrylic	acrylic	NN
cord-010027-r0tl01kq	206	24	-	-	HYPH
cord-010027-r0tl01kq	206	25	based	base	VBN
cord-010027-r0tl01kq	206	26	support	support	NN
cord-010027-r0tl01kq	206	27	and	and	CC
cord-010027-r0tl01kq	206	28	an	an	DT
cord-010027-r0tl01kq	206	29	adaptable	adaptable	JJ
cord-010027-r0tl01kq	206	30	wheelchair	wheelchair	NN
cord-010027-r0tl01kq	206	31	.	.	.
cord-010027-r0tl01kq	207	1	The	the	DT
cord-010027-r0tl01kq	207	2	prototypes	prototype	NNS
cord-010027-r0tl01kq	207	3	were	be	VBD
cord-010027-r0tl01kq	207	4	made	make	VBN
cord-010027-r0tl01kq	207	5	in	in	IN
cord-010027-r0tl01kq	207	6	collaboration	collaboration	NN
cord-010027-r0tl01kq	207	7	with	with	IN
cord-010027-r0tl01kq	207	8	the	the	DT
cord-010027-r0tl01kq	207	9	UCD	UCD	NNP
cord-010027-r0tl01kq	207	10	School	School	NNP
cord-010027-r0tl01kq	207	11	of	of	IN
cord-010027-r0tl01kq	207	12	Engineering	Engineering	NNP
cord-010027-r0tl01kq	207	13	and	and	CC
cord-010027-r0tl01kq	207	14	tested	test	VBD
cord-010027-r0tl01kq	207	15	using	use	VBG
cord-010027-r0tl01kq	207	16	paediatric	paediatric	JJ
cord-010027-r0tl01kq	207	17	phantoms	phantom	NNS
cord-010027-r0tl01kq	207	18	in	in	IN
cord-010027-r0tl01kq	207	19	UCD	UCD	NNP
cord-010027-r0tl01kq	207	20	Radiography	Radiography	NNP
cord-010027-r0tl01kq	207	21	department	department	NN
cord-010027-r0tl01kq	207	22	.	.	.
cord-010027-r0tl01kq	208	1	The	the	DT
cord-010027-r0tl01kq	208	2	final	final	JJ
cord-010027-r0tl01kq	208	3	prototypes	prototype	NNS
cord-010027-r0tl01kq	208	4	will	will	MD
cord-010027-r0tl01kq	208	5	be	be	VB
cord-010027-r0tl01kq	208	6	trialled	trialle	VBN
cord-010027-r0tl01kq	208	7	in	in	IN
cord-010027-r0tl01kq	208	8	Crumlin	Crumlin	NNP
cord-010027-r0tl01kq	208	9	Children	Children	NNP
cord-010027-r0tl01kq	208	10	's	's	POS
cord-010027-r0tl01kq	208	11	Hospital	Hospital	NNP
cord-010027-r0tl01kq	208	12	with	with	IN
cord-010027-r0tl01kq	208	13	a	a	DT
cord-010027-r0tl01kq	208	14	view	view	NN
cord-010027-r0tl01kq	208	15	to	to	IN
cord-010027-r0tl01kq	208	16	future	future	JJ
cord-010027-r0tl01kq	208	17	use	use	NN
cord-010027-r0tl01kq	208	18	and	and	CC
cord-010027-r0tl01kq	208	19	development	development	NN
cord-010027-r0tl01kq	208	20	.	.	.
cord-010027-r0tl01kq	209	1	Thrombotic	thrombotic	JJ
cord-010027-r0tl01kq	209	2	microangiopathy	microangiopathy	NN
cord-010027-r0tl01kq	209	3	(	(	-LRB-
cord-010027-r0tl01kq	209	4	TMA	TMA	NNP
cord-010027-r0tl01kq	209	5	)	)	-RRB-
cord-010027-r0tl01kq	209	6	is	be	VBZ
cord-010027-r0tl01kq	209	7	a	a	DT
cord-010027-r0tl01kq	209	8	pathology	pathology	NN
cord-010027-r0tl01kq	209	9	that	that	WDT
cord-010027-r0tl01kq	209	10	results	result	VBZ
cord-010027-r0tl01kq	209	11	in	in	IN
cord-010027-r0tl01kq	209	12	thrombosis	thrombosis	NN
cord-010027-r0tl01kq	209	13	of	of	IN
cord-010027-r0tl01kq	209	14	capillaries	capillary	NNS
cord-010027-r0tl01kq	209	15	and	and	CC
cord-010027-r0tl01kq	209	16	arterioles	arteriole	NNS
cord-010027-r0tl01kq	209	17	due	due	JJ
cord-010027-r0tl01kq	209	18	to	to	IN
cord-010027-r0tl01kq	209	19	endothelial	endothelial	JJ
cord-010027-r0tl01kq	209	20	injury	injury	NN
cord-010027-r0tl01kq	209	21	.	.	.
cord-010027-r0tl01kq	210	1	It	-PRON-	PRP
cord-010027-r0tl01kq	210	2	is	be	VBZ
cord-010027-r0tl01kq	210	3	usually	usually	RB
cord-010027-r0tl01kq	210	4	characterized	characterize	VBN
cord-010027-r0tl01kq	210	5	by	by	IN
cord-010027-r0tl01kq	210	6	an	an	DT
cord-010027-r0tl01kq	210	7	atypical	atypical	JJ
cord-010027-r0tl01kq	210	8	haemolytic	haemolytic	JJ
cord-010027-r0tl01kq	210	9	syndrome	syndrome	NN
cord-010027-r0tl01kq	210	10	(	(	-LRB-
cord-010027-r0tl01kq	210	11	aHUS	aHUS	NNP
cord-010027-r0tl01kq	210	12	)	)	-RRB-
cord-010027-r0tl01kq	210	13	or	or	CC
cord-010027-r0tl01kq	210	14	thrombotic	thrombotic	JJ
cord-010027-r0tl01kq	210	15	thrombocytopaenic	thrombocytopaenic	NNP
cord-010027-r0tl01kq	210	16	purpura	purpura	NN
cord-010027-r0tl01kq	210	17	(	(	-LRB-
cord-010027-r0tl01kq	210	18	TTP	TTP	NNP
cord-010027-r0tl01kq	210	19	)	)	-RRB-
cord-010027-r0tl01kq	210	20	.	.	.
cord-010027-r0tl01kq	211	1	TMA	TMA	NNP
cord-010027-r0tl01kq	211	2	is	be	VBZ
cord-010027-r0tl01kq	211	3	considered	consider	VBN
cord-010027-r0tl01kq	211	4	to	to	TO
cord-010027-r0tl01kq	211	5	be	be	VB
cord-010027-r0tl01kq	211	6	caused	cause	VBN
cord-010027-r0tl01kq	211	7	by	by	IN
cord-010027-r0tl01kq	211	8	infections	infection	NNS
cord-010027-r0tl01kq	211	9	,	,	,
cord-010027-r0tl01kq	211	10	drugs	drug	NNS
cord-010027-r0tl01kq	211	11	,	,	,
cord-010027-r0tl01kq	211	12	autoimmunity	autoimmunity	NN
cord-010027-r0tl01kq	211	13	,	,	,
cord-010027-r0tl01kq	211	14	tumours	tumour	NNS
cord-010027-r0tl01kq	211	15	,	,	,
cord-010027-r0tl01kq	211	16	pregnancy	pregnancy	NN
cord-010027-r0tl01kq	211	17	,	,	,
cord-010027-r0tl01kq	211	18	transplants	transplant	NNS
cord-010027-r0tl01kq	211	19	and	and	CC
cord-010027-r0tl01kq	211	20	inherited	inherit	VBN
cord-010027-r0tl01kq	211	21	abnormalities	abnormality	NNS
cord-010027-r0tl01kq	211	22	involving	involve	VBG
cord-010027-r0tl01kq	211	23	the	the	DT
cord-010027-r0tl01kq	211	24	alternate	alternate	JJ
cord-010027-r0tl01kq	211	25	complement	complement	NN
cord-010027-r0tl01kq	211	26	pathway	pathway	NN
cord-010027-r0tl01kq	211	27	.	.	.
cord-010027-r0tl01kq	212	1	This	this	DT
cord-010027-r0tl01kq	212	2	presentation	presentation	NN
cord-010027-r0tl01kq	212	3	describes	describe	VBZ
cord-010027-r0tl01kq	212	4	the	the	DT
cord-010027-r0tl01kq	212	5	pathology	pathology	NN
cord-010027-r0tl01kq	212	6	of	of	IN
cord-010027-r0tl01kq	212	7	TMA	TMA	NNP
cord-010027-r0tl01kq	212	8	.	.	.
cord-010027-r0tl01kq	213	1	It	-PRON-	PRP
cord-010027-r0tl01kq	213	2	includes	include	VBZ
cord-010027-r0tl01kq	213	3	a	a	DT
cord-010027-r0tl01kq	213	4	retrospective	retrospective	JJ
cord-010027-r0tl01kq	213	5	15	15	CD
cord-010027-r0tl01kq	213	6	year	year	NN
cord-010027-r0tl01kq	213	7	study	study	NN
cord-010027-r0tl01kq	213	8	(	(	-LRB-
cord-010027-r0tl01kq	213	9	1999	1999	CD
cord-010027-r0tl01kq	213	10	-2013	-2013	NN
cord-010027-r0tl01kq	213	11	)	)	-RRB-
cord-010027-r0tl01kq	213	12	of	of	IN
cord-010027-r0tl01kq	213	13	all	all	DT
cord-010027-r0tl01kq	213	14	renal	renal	JJ
cord-010027-r0tl01kq	213	15	biopsies	biopsy	NNS
cord-010027-r0tl01kq	213	16	reported	report	VBN
cord-010027-r0tl01kq	213	17	by	by	IN
cord-010027-r0tl01kq	213	18	one	one	CD
cord-010027-r0tl01kq	213	19	pathologist	pathologist	NN
cord-010027-r0tl01kq	213	20	.	.	.
cord-010027-r0tl01kq	214	1	All	all	DT
cord-010027-r0tl01kq	214	2	renal	renal	JJ
cord-010027-r0tl01kq	214	3	biopsy	biopsy	NN
cord-010027-r0tl01kq	214	4	request	request	NN
cord-010027-r0tl01kq	214	5	forms	form	NNS
cord-010027-r0tl01kq	214	6	and	and	CC
cord-010027-r0tl01kq	214	7	reports	report	NNS
cord-010027-r0tl01kq	214	8	,	,	,
cord-010027-r0tl01kq	214	9	where	where	WRB
cord-010027-r0tl01kq	214	10	cases	case	NNS
cord-010027-r0tl01kq	214	11	included	include	VBD
cord-010027-r0tl01kq	214	12	light	light	NN
cord-010027-r0tl01kq	214	13	(	(	-LRB-
cord-010027-r0tl01kq	214	14	LM	LM	NNP
cord-010027-r0tl01kq	214	15	)	)	-RRB-
cord-010027-r0tl01kq	214	16	,	,	,
cord-010027-r0tl01kq	214	17	fluorescence(FM	fluorescence(FM	NNP
cord-010027-r0tl01kq	214	18	)	)	-RRB-
cord-010027-r0tl01kq	214	19	and	and	CC
cord-010027-r0tl01kq	214	20	electron	electron	NN
cord-010027-r0tl01kq	214	21	microscopy(EM	microscopy(em	NN
cord-010027-r0tl01kq	214	22	)	)	-RRB-
cord-010027-r0tl01kq	214	23	,	,	,
cord-010027-r0tl01kq	214	24	were	be	VBD
cord-010027-r0tl01kq	214	25	reviewed	review	VBN
cord-010027-r0tl01kq	214	26	.	.	.
cord-010027-r0tl01kq	215	1	Cases	case	NNS
cord-010027-r0tl01kq	215	2	without	without	IN
cord-010027-r0tl01kq	215	3	all	all	DT
cord-010027-r0tl01kq	215	4	3	3	CD
cord-010027-r0tl01kq	215	5	modalitIes	modalities	NN
cord-010027-r0tl01kq	215	6	(	(	-LRB-
cord-010027-r0tl01kq	215	7	LM	LM	NNP
cord-010027-r0tl01kq	215	8	,	,	,
cord-010027-r0tl01kq	215	9	FM	FM	NNP
cord-010027-r0tl01kq	215	10	,	,	,
cord-010027-r0tl01kq	215	11	and	and	CC
cord-010027-r0tl01kq	215	12	EM	EM	NNP
cord-010027-r0tl01kq	215	13	)	)	-RRB-
cord-010027-r0tl01kq	215	14	were	be	VBD
cord-010027-r0tl01kq	215	15	excluded	exclude	VBN
cord-010027-r0tl01kq	215	16	.	.	.
cord-010027-r0tl01kq	216	1	6639	6639	CD
cord-010027-r0tl01kq	216	2	biopsies	biopsy	NNS
cord-010027-r0tl01kq	216	3	were	be	VBD
cord-010027-r0tl01kq	216	4	reported	report	VBN
cord-010027-r0tl01kq	216	5	in	in	IN
cord-010027-r0tl01kq	216	6	the	the	DT
cord-010027-r0tl01kq	216	7	study	study	NN
cord-010027-r0tl01kq	216	8	period	period	NN
cord-010027-r0tl01kq	216	9	(	(	-LRB-
cord-010027-r0tl01kq	216	10	328	328	CD
cord-010027-r0tl01kq	216	11	in	in	IN
cord-010027-r0tl01kq	216	12	1999	1999	CD
cord-010027-r0tl01kq	216	13	(	(	-LRB-
cord-010027-r0tl01kq	216	14	328	328	CD
cord-010027-r0tl01kq	216	15	in	in	IN
cord-010027-r0tl01kq	216	16	to	to	IN
cord-010027-r0tl01kq	216	17	629	629	CD
cord-010027-r0tl01kq	216	18	IN	in	IN
cord-010027-r0tl01kq	216	19	2013	2013	CD
cord-010027-r0tl01kq	216	20	.	.	.
cord-010027-r0tl01kq	217	1	2105	2105	CD
cord-010027-r0tl01kq	217	2	were	be	VBD
cord-010027-r0tl01kq	217	3	transplant	transplant	NN
cord-010027-r0tl01kq	217	4	biopsies	biopsy	NNS
cord-010027-r0tl01kq	217	5	.	.	.
cord-010027-r0tl01kq	218	1	284	284	CD
cord-010027-r0tl01kq	218	2	biopsies	biopsy	NNS
cord-010027-r0tl01kq	218	3	were	be	VBD
cord-010027-r0tl01kq	218	4	insufficient	insufficient	JJ
cord-010027-r0tl01kq	218	5	(	(	-LRB-
cord-010027-r0tl01kq	218	6	LM	LM	NNP
cord-010027-r0tl01kq	218	7	,	,	,
cord-010027-r0tl01kq	218	8	FM	FM	NNP
cord-010027-r0tl01kq	218	9	and	and	CC
cord-010027-r0tl01kq	218	10	EM	EM	NNP
cord-010027-r0tl01kq	218	11	all	all	DT
cord-010027-r0tl01kq	218	12	not	not	RB
cord-010027-r0tl01kq	218	13	possible	possible	JJ
cord-010027-r0tl01kq	218	14	.	.	.
cord-010027-r0tl01kq	219	1	This	this	DT
cord-010027-r0tl01kq	219	2	resulted	result	VBD
cord-010027-r0tl01kq	219	3	in	in	IN
cord-010027-r0tl01kq	219	4	4250	4250	CD
cord-010027-r0tl01kq	219	5	native	native	JJ
cord-010027-r0tl01kq	219	6	renal	renal	JJ
cord-010027-r0tl01kq	219	7	biopsies	biopsy	NNS
cord-010027-r0tl01kq	219	8	as	as	IN
cord-010027-r0tl01kq	219	9	the	the	DT
cord-010027-r0tl01kq	219	10	study	study	NN
cord-010027-r0tl01kq	219	11	group	group	NN
cord-010027-r0tl01kq	219	12	.	.	.
cord-010027-r0tl01kq	220	1	Following	follow	VBG
cord-010027-r0tl01kq	220	2	review	review	NN
cord-010027-r0tl01kq	220	3	of	of	IN
cord-010027-r0tl01kq	220	4	the	the	DT
cord-010027-r0tl01kq	220	5	reports	report	NNS
cord-010027-r0tl01kq	220	6	641	641	CD
cord-010027-r0tl01kq	220	7	cases	case	NNS
cord-010027-r0tl01kq	220	8	were	be	VBD
cord-010027-r0tl01kq	220	9	reported	report	VBN
cord-010027-r0tl01kq	220	10	as	as	IN
cord-010027-r0tl01kq	220	11	TMA	TMA	NNP
cord-010027-r0tl01kq	220	12	.	.	.
cord-010027-r0tl01kq	221	1	66	66	CD
cord-010027-r0tl01kq	221	2	were	be	VBD
cord-010027-r0tl01kq	221	3	associated	associate	VBN
cord-010027-r0tl01kq	221	4	with	with	IN
cord-010027-r0tl01kq	221	5	thin	thin	JJ
cord-010027-r0tl01kq	221	6	membrane	membrane	NN
cord-010027-r0tl01kq	221	7	nephropathy	nephropathy	NN
cord-010027-r0tl01kq	221	8	,	,	,
cord-010027-r0tl01kq	221	9	41	41	CD
cord-010027-r0tl01kq	221	10	with	with	IN
cord-010027-r0tl01kq	221	11	minimal	minimal	JJ
cord-010027-r0tl01kq	221	12	change	change	NN
cord-010027-r0tl01kq	221	13	disease	disease	NN
cord-010027-r0tl01kq	221	14	and	and	CC
cord-010027-r0tl01kq	221	15	24	24	CD
cord-010027-r0tl01kq	221	16	with	with	IN
cord-010027-r0tl01kq	221	17	plasma	plasma	NN
cord-010027-r0tl01kq	221	18	cell	cell	NN
cord-010027-r0tl01kq	221	19	dyscrasia/	dyscrasia/	CD
cord-010027-r0tl01kq	221	20	B	b	NN
cord-010027-r0tl01kq	221	21	cell	cell	NN
cord-010027-r0tl01kq	221	22	malignancy	malignancy	NN
cord-010027-r0tl01kq	221	23	.	.	.
cord-010027-r0tl01kq	222	1	This	this	DT
cord-010027-r0tl01kq	222	2	resulted	result	VBD
cord-010027-r0tl01kq	222	3	in	in	IN
cord-010027-r0tl01kq	222	4	510	510	CD
cord-010027-r0tl01kq	222	5	cases	case	NNS
cord-010027-r0tl01kq	222	6	with	with	IN
cord-010027-r0tl01kq	222	7	TMA	TMA	NNP
cord-010027-r0tl01kq	222	8	as	as	IN
cord-010027-r0tl01kq	222	9	the	the	DT
cord-010027-r0tl01kq	222	10	only	only	JJ
cord-010027-r0tl01kq	222	11	pathology	pathology	NN
cord-010027-r0tl01kq	222	12	reported	report	VBD
cord-010027-r0tl01kq	222	13	which	which	WDT
cord-010027-r0tl01kq	222	14	represents	represent	VBZ
cord-010027-r0tl01kq	222	15	12	12	CD
cord-010027-r0tl01kq	222	16	%	%	NN
cord-010027-r0tl01kq	222	17	of	of	IN
cord-010027-r0tl01kq	222	18	all	all	DT
cord-010027-r0tl01kq	222	19	adequate	adequate	JJ
cord-010027-r0tl01kq	222	20	native	native	JJ
cord-010027-r0tl01kq	222	21	medical	medical	JJ
cord-010027-r0tl01kq	222	22	renal	renal	JJ
cord-010027-r0tl01kq	222	23	biopsies	biopsy	NNS
cord-010027-r0tl01kq	222	24	.	.	.
cord-010027-r0tl01kq	223	1	Clinical	clinical	JJ
cord-010027-r0tl01kq	223	2	indications	indication	NNS
cord-010027-r0tl01kq	223	3	included	include	VBD
cord-010027-r0tl01kq	223	4	proteinuria	proteinuria	NN
cord-010027-r0tl01kq	223	5	in	in	IN
cord-010027-r0tl01kq	223	6	73	73	CD
cord-010027-r0tl01kq	223	7	%	%	NN
cord-010027-r0tl01kq	223	8	,	,	,
cord-010027-r0tl01kq	223	9	nephrotic	nephrotic	JJ
cord-010027-r0tl01kq	223	10	syndrome	syndrome	NN
cord-010027-r0tl01kq	223	11	in	in	IN
cord-010027-r0tl01kq	223	12	15	15	CD
cord-010027-r0tl01kq	223	13	%	%	NN
cord-010027-r0tl01kq	223	14	,	,	,
cord-010027-r0tl01kq	223	15	increased	increase	VBN
cord-010027-r0tl01kq	223	16	creatinine	creatinine	NN
cord-010027-r0tl01kq	223	17	in	in	IN
cord-010027-r0tl01kq	223	18	43	43	CD
cord-010027-r0tl01kq	223	19	%	%	NN
cord-010027-r0tl01kq	223	20	,	,	,
cord-010027-r0tl01kq	223	21	increased	increase	VBN
cord-010027-r0tl01kq	223	22	blood	blood	NN
cord-010027-r0tl01kq	223	23	pressure	pressure	NN
cord-010027-r0tl01kq	223	24	in	in	IN
cord-010027-r0tl01kq	223	25	55	55	CD
cord-010027-r0tl01kq	223	26	%	%	NN
cord-010027-r0tl01kq	223	27	and	and	CC
cord-010027-r0tl01kq	223	28	haematuria	haematuria	NN
cord-010027-r0tl01kq	223	29	in	in	IN
cord-010027-r0tl01kq	223	30	43	43	CD
cord-010027-r0tl01kq	223	31	%	%	NN
cord-010027-r0tl01kq	223	32	of	of	IN
cord-010027-r0tl01kq	223	33	the	the	DT
cord-010027-r0tl01kq	223	34	cases	case	NNS
cord-010027-r0tl01kq	223	35	.	.	.
cord-010027-r0tl01kq	224	1	Acute	acute	JJ
cord-010027-r0tl01kq	224	2	renal	renal	JJ
cord-010027-r0tl01kq	224	3	failure	failure	NN
cord-010027-r0tl01kq	224	4	was	be	VBD
cord-010027-r0tl01kq	224	5	described	describe	VBN
cord-010027-r0tl01kq	224	6	in	in	IN
cord-010027-r0tl01kq	224	7	10	10	CD
cord-010027-r0tl01kq	224	8	%	%	NN
cord-010027-r0tl01kq	224	9	and	and	CC
cord-010027-r0tl01kq	224	10	HUS	HUS	NNP
cord-010027-r0tl01kq	224	11	in	in	IN
cord-010027-r0tl01kq	224	12	just	just	RB
cord-010027-r0tl01kq	224	13	1	1	CD
cord-010027-r0tl01kq	224	14	%	%	NN
cord-010027-r0tl01kq	224	15	of	of	IN
cord-010027-r0tl01kq	224	16	the	the	DT
cord-010027-r0tl01kq	224	17	cases	case	NNS
cord-010027-r0tl01kq	224	18	.	.	.
cord-010027-r0tl01kq	225	1	Pathological	pathological	JJ
cord-010027-r0tl01kq	225	2	changes	change	NNS
cord-010027-r0tl01kq	225	3	were	be	VBD
cord-010027-r0tl01kq	225	4	predominently	predominently	RB
cord-010027-r0tl01kq	225	5	arteriolar	arteriolar	JJ
cord-010027-r0tl01kq	225	6	sclerosis	sclerosis	NN
cord-010027-r0tl01kq	225	7	and	and	CC
cord-010027-r0tl01kq	225	8	glomerular	glomerular	JJ
cord-010027-r0tl01kq	225	9	double	double	JJ
cord-010027-r0tl01kq	225	10	contours	contour	NNS
cord-010027-r0tl01kq	225	11	on	on	IN
cord-010027-r0tl01kq	225	12	LM	LM	NNP
cord-010027-r0tl01kq	225	13	with	with	IN
cord-010027-r0tl01kq	225	14	chronic	chronic	JJ
cord-010027-r0tl01kq	225	15	subendothelial	subendothelial	JJ
cord-010027-r0tl01kq	225	16	injury	injury	NN
cord-010027-r0tl01kq	225	17	on	on	IN
cord-010027-r0tl01kq	225	18	EM	EM	NNP
cord-010027-r0tl01kq	225	19	.	.	.
cord-010027-r0tl01kq	226	1	The	the	DT
cord-010027-r0tl01kq	226	2	conclusions	conclusion	NNS
cord-010027-r0tl01kq	226	3	of	of	IN
cord-010027-r0tl01kq	226	4	this	this	DT
cord-010027-r0tl01kq	226	5	presentation	presentation	NN
cord-010027-r0tl01kq	226	6	are	be	VBP
cord-010027-r0tl01kq	226	7	1	1	CD
cord-010027-r0tl01kq	226	8	.	.	.
cord-010027-r0tl01kq	227	1	TMA	TMA	NNP
cord-010027-r0tl01kq	227	2	is	be	VBZ
cord-010027-r0tl01kq	227	3	overwhelmingly	overwhelmingly	RB
cord-010027-r0tl01kq	227	4	a	a	DT
cord-010027-r0tl01kq	227	5	chronic	chronic	JJ
cord-010027-r0tl01kq	227	6	lesion	lesion	NN
cord-010027-r0tl01kq	227	7	as	as	IN
cord-010027-r0tl01kq	227	8	seen	see	VBN
cord-010027-r0tl01kq	227	9	in	in	IN
cord-010027-r0tl01kq	227	10	renal	renal	JJ
cord-010027-r0tl01kq	227	11	biopsy	biopsy	NN
cord-010027-r0tl01kq	227	12	pathology	pathology	NN
cord-010027-r0tl01kq	227	13	.	.	.
cord-010027-r0tl01kq	228	1	2	2	LS
cord-010027-r0tl01kq	228	2	.	.	.
cord-010027-r0tl01kq	229	1	It	-PRON-	PRP
cord-010027-r0tl01kq	229	2	is	be	VBZ
cord-010027-r0tl01kq	229	3	a	a	DT
cord-010027-r0tl01kq	229	4	very	very	RB
cord-010027-r0tl01kq	229	5	common	common	JJ
cord-010027-r0tl01kq	229	6	pattern	pattern	NN
cord-010027-r0tl01kq	229	7	of	of	IN
cord-010027-r0tl01kq	229	8	injury	injury	NN
cord-010027-r0tl01kq	229	9	.	.	.
cord-010027-r0tl01kq	230	1	3	3	LS
cord-010027-r0tl01kq	230	2	.	.	.
cord-010027-r0tl01kq	231	1	It	-PRON-	PRP
cord-010027-r0tl01kq	231	2	is	be	VBZ
cord-010027-r0tl01kq	231	3	not	not	RB
cord-010027-r0tl01kq	231	4	usually	usually	RB
cord-010027-r0tl01kq	231	5	associated	associate	VBN
cord-010027-r0tl01kq	231	6	with	with	IN
cord-010027-r0tl01kq	231	7	clinical	clinical	JJ
cord-010027-r0tl01kq	231	8	HUS	hus	NN
cord-010027-r0tl01kq	231	9	or	or	CC
cord-010027-r0tl01kq	231	10	TTP	ttp	NN
cord-010027-r0tl01kq	231	11	features	feature	NNS
cord-010027-r0tl01kq	231	12	at	at	IN
cord-010027-r0tl01kq	231	13	presentation	presentation	NN
cord-010027-r0tl01kq	231	14	.	.	.
cord-010027-r0tl01kq	232	1	The	the	DT
cord-010027-r0tl01kq	232	2	era	era	NN
cord-010027-r0tl01kq	232	3	of	of	IN
cord-010027-r0tl01kq	232	4	targeted	target	VBN
cord-010027-r0tl01kq	232	5	cancer	cancer	NN
cord-010027-r0tl01kq	232	6	therapeutics	therapeutic	NNS
cord-010027-r0tl01kq	232	7	has	have	VBZ
cord-010027-r0tl01kq	232	8	brought	bring	VBN
cord-010027-r0tl01kq	232	9	forth	forth	RP
cord-010027-r0tl01kq	232	10	new	new	JJ
cord-010027-r0tl01kq	232	11	challenges	challenge	NNS
cord-010027-r0tl01kq	232	12	for	for	IN
cord-010027-r0tl01kq	232	13	molecular	molecular	JJ
cord-010027-r0tl01kq	232	14	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	232	15	laboratories	laboratory	NNS
cord-010027-r0tl01kq	232	16	.	.	.
cord-010027-r0tl01kq	233	1	The	the	DT
cord-010027-r0tl01kq	233	2	list	list	NN
cord-010027-r0tl01kq	233	3	of	of	IN
cord-010027-r0tl01kq	233	4	genes	gene	NNS
cord-010027-r0tl01kq	233	5	,	,	,
cord-010027-r0tl01kq	233	6	and	and	CC
cord-010027-r0tl01kq	233	7	indeed	indeed	RB
cord-010027-r0tl01kq	233	8	specific	specific	JJ
cord-010027-r0tl01kq	233	9	mutations	mutation	NNS
cord-010027-r0tl01kq	233	10	,	,	,
cord-010027-r0tl01kq	233	11	that	that	WDT
cord-010027-r0tl01kq	233	12	predict	predict	VBP
cord-010027-r0tl01kq	233	13	drug	drug	NN
cord-010027-r0tl01kq	233	14	responses	response	NNS
cord-010027-r0tl01kq	233	15	keeps	keep	VBZ
cord-010027-r0tl01kq	233	16	growing	grow	VBG
cord-010027-r0tl01kq	233	17	,	,	,
cord-010027-r0tl01kq	233	18	and	and	CC
cord-010027-r0tl01kq	233	19	with	with	IN
cord-010027-r0tl01kq	233	20	it	-PRON-	PRP
cord-010027-r0tl01kq	233	21	grows	grow	VBZ
cord-010027-r0tl01kq	233	22	the	the	DT
cord-010027-r0tl01kq	233	23	demand	demand	NN
cord-010027-r0tl01kq	233	24	for	for	IN
cord-010027-r0tl01kq	233	25	molecular	molecular	JJ
cord-010027-r0tl01kq	233	26	sub	sub	NN
cord-010027-r0tl01kq	233	27	-	-	NN
cord-010027-r0tl01kq	233	28	classification	classification	NN
cord-010027-r0tl01kq	233	29	of	of	IN
cord-010027-r0tl01kq	233	30	tumors	tumor	NNS
cord-010027-r0tl01kq	233	31	.	.	.
cord-010027-r0tl01kq	234	1	In	in	IN
cord-010027-r0tl01kq	234	2	colorectal	colorectal	JJ
cord-010027-r0tl01kq	234	3	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	234	4	,	,	,
cord-010027-r0tl01kq	234	5	for	for	IN
cord-010027-r0tl01kq	234	6	example	example	NN
cord-010027-r0tl01kq	234	7	,	,	,
cord-010027-r0tl01kq	234	8	recent	recent	JJ
cord-010027-r0tl01kq	234	9	studies	study	NNS
cord-010027-r0tl01kq	234	10	support	support	VBP
cord-010027-r0tl01kq	234	11	expanding	expand	VBG
cord-010027-r0tl01kq	234	12	testing	testing	NN
cord-010027-r0tl01kq	234	13	beyond	beyond	IN
cord-010027-r0tl01kq	234	14	KRAS	kra	NNS
cord-010027-r0tl01kq	234	15	to	to	TO
cord-010027-r0tl01kq	234	16	include	include	VB
cord-010027-r0tl01kq	234	17	NRAS	NRAS	NNP
cord-010027-r0tl01kq	234	18	and	and	CC
cord-010027-r0tl01kq	234	19	BRAF	BRAF	NNP
cord-010027-r0tl01kq	234	20	in	in	IN
cord-010027-r0tl01kq	234	21	predicting	predict	VBG
cord-010027-r0tl01kq	234	22	resistance	resistance	NN
cord-010027-r0tl01kq	234	23	to	to	IN
cord-010027-r0tl01kq	234	24	EGFR	EGFR	NNP
cord-010027-r0tl01kq	234	25	-	-	HYPH
cord-010027-r0tl01kq	234	26	targeted	target	VBN
cord-010027-r0tl01kq	234	27	therapies	therapy	NNS
cord-010027-r0tl01kq	234	28	.	.	.
cord-010027-r0tl01kq	235	1	Similarly	similarly	RB
cord-010027-r0tl01kq	235	2	,	,	,
cord-010027-r0tl01kq	235	3	in	in	IN
cord-010027-r0tl01kq	235	4	non	non	JJ
cord-010027-r0tl01kq	235	5	-	-	JJ
cord-010027-r0tl01kq	235	6	small	small	JJ
cord-010027-r0tl01kq	235	7	cell	cell	NN
cord-010027-r0tl01kq	235	8	lung	lung	NN
cord-010027-r0tl01kq	235	9	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	235	10	standard	standard	JJ
cord-010027-r0tl01kq	235	11	screening	screening	NN
cord-010027-r0tl01kq	235	12	for	for	IN
cord-010027-r0tl01kq	235	13	EGFR	EGFR	NNP
cord-010027-r0tl01kq	235	14	mutations	mutation	NNS
cord-010027-r0tl01kq	235	15	and	and	CC
cord-010027-r0tl01kq	235	16	ALK	ALK	NNP
cord-010027-r0tl01kq	235	17	gene	gene	NN
cord-010027-r0tl01kq	235	18	fusions	fusion	NNS
cord-010027-r0tl01kq	235	19	may	may	MD
cord-010027-r0tl01kq	235	20	be	be	VB
cord-010027-r0tl01kq	235	21	insufficient	insufficient	JJ
cord-010027-r0tl01kq	235	22	when	when	WRB
cord-010027-r0tl01kq	235	23	actionable	actionable	JJ
cord-010027-r0tl01kq	235	24	alterations	alteration	NNS
cord-010027-r0tl01kq	235	25	involving	involve	VBG
cord-010027-r0tl01kq	235	26	ROS1	ROS1	NNP
cord-010027-r0tl01kq	235	27	,	,	,
cord-010027-r0tl01kq	235	28	RET	RET	NNP
cord-010027-r0tl01kq	235	29	,	,	,
cord-010027-r0tl01kq	235	30	HER2	HER2	NNP
cord-010027-r0tl01kq	235	31	,	,	,
cord-010027-r0tl01kq	235	32	MET	MET	NNP
cord-010027-r0tl01kq	235	33	,	,	,
cord-010027-r0tl01kq	235	34	BRAF	BRAF	NNP
cord-010027-r0tl01kq	235	35	and	and	CC
cord-010027-r0tl01kq	235	36	other	other	JJ
cord-010027-r0tl01kq	235	37	genes	gene	NNS
cord-010027-r0tl01kq	235	38	are	be	VBP
cord-010027-r0tl01kq	235	39	being	be	VBG
cord-010027-r0tl01kq	235	40	targeted	target	VBN
cord-010027-r0tl01kq	235	41	(	(	-LRB-
cord-010027-r0tl01kq	235	42	successfully	successfully	RB
cord-010027-r0tl01kq	235	43	)	)	-RRB-
cord-010027-r0tl01kq	235	44	in	in	IN
cord-010027-r0tl01kq	235	45	ongoing	ongoing	JJ
cord-010027-r0tl01kq	235	46	clinical	clinical	JJ
cord-010027-r0tl01kq	235	47	trials	trial	NNS
cord-010027-r0tl01kq	235	48	.	.	.
cord-010027-r0tl01kq	236	1	Fortunately	fortunately	RB
cord-010027-r0tl01kq	236	2	,	,	,
cord-010027-r0tl01kq	236	3	the	the	DT
cord-010027-r0tl01kq	236	4	introduction	introduction	NN
cord-010027-r0tl01kq	236	5	of	of	IN
cord-010027-r0tl01kq	236	6	next	next	JJ
cord-010027-r0tl01kq	236	7	-	-	HYPH
cord-010027-r0tl01kq	236	8	generation	generation	NN
cord-010027-r0tl01kq	236	9	sequencing	sequencing	NN
cord-010027-r0tl01kq	236	10	(	(	-LRB-
cord-010027-r0tl01kq	236	11	NGS	NGS	NNP
cord-010027-r0tl01kq	236	12	)	)	-RRB-
cord-010027-r0tl01kq	236	13	into	into	IN
cord-010027-r0tl01kq	236	14	the	the	DT
cord-010027-r0tl01kq	236	15	clinical	clinical	JJ
cord-010027-r0tl01kq	236	16	laboratory	laboratory	NN
cord-010027-r0tl01kq	236	17	is	be	VBZ
cord-010027-r0tl01kq	236	18	meeting	meet	VBG
cord-010027-r0tl01kq	236	19	the	the	DT
cord-010027-r0tl01kq	236	20	demand	demand	NN
cord-010027-r0tl01kq	236	21	.	.	.
cord-010027-r0tl01kq	237	1	Due	due	IN
cord-010027-r0tl01kq	237	2	to	to	IN
cord-010027-r0tl01kq	237	3	its	-PRON-	PRP$
cord-010027-r0tl01kq	237	4	quantitative	quantitative	JJ
cord-010027-r0tl01kq	237	5	output	output	NN
cord-010027-r0tl01kq	237	6	,	,	,
cord-010027-r0tl01kq	237	7	NGS	NGS	NNP
cord-010027-r0tl01kq	237	8	not	not	RB
cord-010027-r0tl01kq	237	9	only	only	RB
cord-010027-r0tl01kq	237	10	provides	provide	VBZ
cord-010027-r0tl01kq	237	11	precise	precise	JJ
cord-010027-r0tl01kq	237	12	mutant	mutant	JJ
cord-010027-r0tl01kq	237	13	allele	allele	NN
cord-010027-r0tl01kq	237	14	ratios	ratio	NNS
cord-010027-r0tl01kq	237	15	,	,	,
cord-010027-r0tl01kq	237	16	but	but	CC
cord-010027-r0tl01kq	237	17	it	-PRON-	PRP
cord-010027-r0tl01kq	237	18	can	can	MD
cord-010027-r0tl01kq	237	19	also	also	RB
cord-010027-r0tl01kq	237	20	be	be	VB
cord-010027-r0tl01kq	237	21	used	use	VBN
cord-010027-r0tl01kq	237	22	to	to	TO
cord-010027-r0tl01kq	237	23	detect	detect	VB
cord-010027-r0tl01kq	237	24	gene	gene	NN
cord-010027-r0tl01kq	237	25	gains	gain	NNS
cord-010027-r0tl01kq	237	26	and	and	CC
cord-010027-r0tl01kq	237	27	losses	loss	NNS
cord-010027-r0tl01kq	237	28	.	.	.
cord-010027-r0tl01kq	238	1	Furthermore	furthermore	RB
cord-010027-r0tl01kq	238	2	,	,	,
cord-010027-r0tl01kq	238	3	when	when	WRB
cord-010027-r0tl01kq	238	4	applied	apply	VBN
cord-010027-r0tl01kq	238	5	to	to	IN
cord-010027-r0tl01kq	238	6	RNA	RNA	NNP
cord-010027-r0tl01kq	238	7	,	,	,
cord-010027-r0tl01kq	238	8	NGS	NGS	NNP
cord-010027-r0tl01kq	238	9	supports	support	VBZ
cord-010027-r0tl01kq	238	10	the	the	DT
cord-010027-r0tl01kq	238	11	detection	detection	NN
cord-010027-r0tl01kq	238	12	of	of	IN
cord-010027-r0tl01kq	238	13	gene	gene	NN
cord-010027-r0tl01kq	238	14	fusions	fusion	NNS
cord-010027-r0tl01kq	238	15	and	and	CC
cord-010027-r0tl01kq	238	16	serves	serve	VBZ
cord-010027-r0tl01kq	238	17	in	in	IN
cord-010027-r0tl01kq	238	18	assessing	assess	VBG
cord-010027-r0tl01kq	238	19	gene	gene	NN
cord-010027-r0tl01kq	238	20	expression	expression	NN
cord-010027-r0tl01kq	238	21	levels	level	NNS
cord-010027-r0tl01kq	238	22	.	.	.
cord-010027-r0tl01kq	239	1	While	while	IN
cord-010027-r0tl01kq	239	2	NGS	NGS	NNP
cord-010027-r0tl01kq	239	3	is	be	VBZ
cord-010027-r0tl01kq	239	4	a	a	DT
cord-010027-r0tl01kq	239	5	powerful	powerful	JJ
cord-010027-r0tl01kq	239	6	tool	tool	NN
cord-010027-r0tl01kq	239	7	for	for	IN
cord-010027-r0tl01kq	239	8	molecularly	molecularly	RB
cord-010027-r0tl01kq	239	9	characterizing	characterize	VBG
cord-010027-r0tl01kq	239	10	solid	solid	JJ
cord-010027-r0tl01kq	239	11	tumors	tumor	NNS
cord-010027-r0tl01kq	239	12	,	,	,
cord-010027-r0tl01kq	239	13	the	the	DT
cord-010027-r0tl01kq	239	14	quality	quality	NN
cord-010027-r0tl01kq	239	15	of	of	IN
cord-010027-r0tl01kq	239	16	the	the	DT
cord-010027-r0tl01kq	239	17	results	result	NNS
cord-010027-r0tl01kq	239	18	in	in	IN
cord-010027-r0tl01kq	239	19	large	large	JJ
cord-010027-r0tl01kq	239	20	part	part	NN
cord-010027-r0tl01kq	239	21	rests	rest	VBZ
cord-010027-r0tl01kq	239	22	on	on	IN
cord-010027-r0tl01kq	239	23	the	the	DT
cord-010027-r0tl01kq	239	24	selection	selection	NN
cord-010027-r0tl01kq	239	25	of	of	IN
cord-010027-r0tl01kq	239	26	appropriate	appropriate	JJ
cord-010027-r0tl01kq	239	27	input	input	NN
cord-010027-r0tl01kq	239	28	material	material	NN
cord-010027-r0tl01kq	239	29	;	;	:
cord-010027-r0tl01kq	239	30	therefore	therefore	RB
cord-010027-r0tl01kq	239	31	,	,	,
cord-010027-r0tl01kq	239	32	review	review	NN
cord-010027-r0tl01kq	239	33	by	by	IN
cord-010027-r0tl01kq	239	34	a	a	DT
cord-010027-r0tl01kq	239	35	pathologist	pathologist	NN
cord-010027-r0tl01kq	239	36	prior	prior	RB
cord-010027-r0tl01kq	239	37	to	to	IN
cord-010027-r0tl01kq	239	38	testing	testing	NN
cord-010027-r0tl01kq	239	39	remains	remain	VBZ
cord-010027-r0tl01kq	239	40	a	a	DT
cord-010027-r0tl01kq	239	41	cornerstone	cornerstone	NN
cord-010027-r0tl01kq	239	42	to	to	IN
cord-010027-r0tl01kq	239	43	success	success	NN
cord-010027-r0tl01kq	239	44	.	.	.
cord-010027-r0tl01kq	240	1	Other	other	JJ
cord-010027-r0tl01kq	240	2	growing	grow	VBG
cord-010027-r0tl01kq	240	3	uses	use	NNS
cord-010027-r0tl01kq	240	4	of	of	IN
cord-010027-r0tl01kq	240	5	NGS	NGS	NNP
cord-010027-r0tl01kq	240	6	include	include	VBP
cord-010027-r0tl01kq	240	7	monitoring	monitor	VBG
cord-010027-r0tl01kq	240	8	minimal	minimal	JJ
cord-010027-r0tl01kq	240	9	residual	residual	JJ
cord-010027-r0tl01kq	240	10	disease	disease	NN
cord-010027-r0tl01kq	240	11	in	in	IN
cord-010027-r0tl01kq	240	12	the	the	DT
cord-010027-r0tl01kq	240	13	setting	setting	NN
cord-010027-r0tl01kq	240	14	of	of	IN
cord-010027-r0tl01kq	240	15	hematologic	hematologic	JJ
cord-010027-r0tl01kq	240	16	malignancies	malignancy	NNS
cord-010027-r0tl01kq	240	17	,	,	,
cord-010027-r0tl01kq	240	18	and	and	CC
cord-010027-r0tl01kq	240	19	in	in	IN
cord-010027-r0tl01kq	240	20	the	the	DT
cord-010027-r0tl01kq	240	21	detection	detection	NN
cord-010027-r0tl01kq	240	22	of	of	IN
cord-010027-r0tl01kq	240	23	targetable	targetable	JJ
cord-010027-r0tl01kq	240	24	mutations	mutation	NNS
cord-010027-r0tl01kq	240	25	in	in	IN
cord-010027-r0tl01kq	240	26	cell	cell	NN
cord-010027-r0tl01kq	240	27	-	-	HYPH
cord-010027-r0tl01kq	240	28	free	free	JJ
cord-010027-r0tl01kq	240	29	DNA	dna	NN
cord-010027-r0tl01kq	240	30	within	within	IN
cord-010027-r0tl01kq	240	31	the	the	DT
cord-010027-r0tl01kq	240	32	plasma	plasma	NN
cord-010027-r0tl01kq	240	33	.	.	.
cord-010027-r0tl01kq	241	1	The	the	DT
cord-010027-r0tl01kq	241	2	advent	advent	NN
cord-010027-r0tl01kq	241	3	of	of	IN
cord-010027-r0tl01kq	241	4	next	next	JJ
cord-010027-r0tl01kq	241	5	generation	generation	NN
cord-010027-r0tl01kq	241	6	sequencing	sequencing	NN
cord-010027-r0tl01kq	241	7	has	have	VBZ
cord-010027-r0tl01kq	241	8	ushered	usher	VBN
cord-010027-r0tl01kq	241	9	in	in	RP
cord-010027-r0tl01kq	241	10	an	an	DT
cord-010027-r0tl01kq	241	11	era	era	NN
cord-010027-r0tl01kq	241	12	of	of	IN
cord-010027-r0tl01kq	241	13	tremendous	tremendous	JJ
cord-010027-r0tl01kq	241	14	potential	potential	NN
cord-010027-r0tl01kq	241	15	for	for	IN
cord-010027-r0tl01kq	241	16	identifying	identify	VBG
cord-010027-r0tl01kq	241	17	the	the	DT
cord-010027-r0tl01kq	241	18	molecular	molecular	JJ
cord-010027-r0tl01kq	241	19	causation	causation	NN
cord-010027-r0tl01kq	241	20	of	of	IN
cord-010027-r0tl01kq	241	21	simple	simple	JJ
cord-010027-r0tl01kq	241	22	and	and	CC
cord-010027-r0tl01kq	241	23	complex	complex	JJ
cord-010027-r0tl01kq	241	24	disorders	disorder	NNS
cord-010027-r0tl01kq	241	25	,	,	,
cord-010027-r0tl01kq	241	26	both	both	CC
cord-010027-r0tl01kq	241	27	rare	rare	JJ
cord-010027-r0tl01kq	241	28	and	and	CC
cord-010027-r0tl01kq	241	29	common	common	JJ
cord-010027-r0tl01kq	241	30	.	.	.
cord-010027-r0tl01kq	242	1	The	the	DT
cord-010027-r0tl01kq	242	2	successes	success	NNS
cord-010027-r0tl01kq	242	3	of	of	IN
cord-010027-r0tl01kq	242	4	next	next	JJ
cord-010027-r0tl01kq	242	5	generation	generation	NN
cord-010027-r0tl01kq	242	6	sequencing	sequencing	NN
cord-010027-r0tl01kq	242	7	reflect	reflect	VBP
cord-010027-r0tl01kq	242	8	the	the	DT
cord-010027-r0tl01kq	242	9	combined	combine	VBN
cord-010027-r0tl01kq	242	10	interpretive	interpretive	JJ
cord-010027-r0tl01kq	242	11	skills	skill	NNS
cord-010027-r0tl01kq	242	12	of	of	IN
cord-010027-r0tl01kq	242	13	geneticists	geneticist	NNS
cord-010027-r0tl01kq	242	14	,	,	,
cord-010027-r0tl01kq	242	15	bioinformaticians	bioinformatician	NNS
cord-010027-r0tl01kq	242	16	and	and	CC
cord-010027-r0tl01kq	242	17	clinicians	clinician	NNS
cord-010027-r0tl01kq	242	18	working	work	VBG
cord-010027-r0tl01kq	242	19	in	in	IN
cord-010027-r0tl01kq	242	20	close	close	JJ
cord-010027-r0tl01kq	242	21	collaboration	collaboration	NN
cord-010027-r0tl01kq	242	22	.	.	.
cord-010027-r0tl01kq	243	1	In	in	IN
cord-010027-r0tl01kq	243	2	the	the	DT
cord-010027-r0tl01kq	243	3	realm	realm	NN
cord-010027-r0tl01kq	243	4	of	of	IN
cord-010027-r0tl01kq	243	5	muscle	muscle	NN
cord-010027-r0tl01kq	243	6	disease	disease	NN
cord-010027-r0tl01kq	243	7	,	,	,
cord-010027-r0tl01kq	243	8	we	-PRON-	PRP
cord-010027-r0tl01kq	243	9	have	have	VBP
cord-010027-r0tl01kq	243	10	witnessed	witness	VBN
cord-010027-r0tl01kq	243	11	both	both	PDT
cord-010027-r0tl01kq	243	12	the	the	DT
cord-010027-r0tl01kq	243	13	strengths	strength	NNS
cord-010027-r0tl01kq	243	14	and	and	CC
cord-010027-r0tl01kq	243	15	the	the	DT
cord-010027-r0tl01kq	243	16	weaknesses	weakness	NNS
cord-010027-r0tl01kq	243	17	of	of	IN
cord-010027-r0tl01kq	243	18	next	next	JJ
cord-010027-r0tl01kq	243	19	generation	generation	NN
cord-010027-r0tl01kq	243	20	sequencing	sequencing	NN
cord-010027-r0tl01kq	243	21	technologies	technology	NNS
cord-010027-r0tl01kq	243	22	.	.	.
cord-010027-r0tl01kq	244	1	The	the	DT
cord-010027-r0tl01kq	244	2	use	use	NN
cord-010027-r0tl01kq	244	3	of	of	IN
cord-010027-r0tl01kq	244	4	exome	exome	NN
cord-010027-r0tl01kq	244	5	sequencing	sequencing	NN
cord-010027-r0tl01kq	244	6	in	in	IN
cord-010027-r0tl01kq	244	7	patients	patient	NNS
cord-010027-r0tl01kq	244	8	with	with	IN
cord-010027-r0tl01kq	244	9	rare	rare	JJ
cord-010027-r0tl01kq	244	10	muscle	muscle	NN
cord-010027-r0tl01kq	244	11	disease	disease	NN
cord-010027-r0tl01kq	244	12	who	who	WP
cord-010027-r0tl01kq	244	13	have	have	VBP
cord-010027-r0tl01kq	244	14	been	be	VBN
cord-010027-r0tl01kq	244	15	carefully	carefully	RB
cord-010027-r0tl01kq	244	16	phenotyped	phenotype	VBN
cord-010027-r0tl01kq	244	17	has	have	VBZ
cord-010027-r0tl01kq	244	18	proven	prove	VBN
cord-010027-r0tl01kq	244	19	to	to	TO
cord-010027-r0tl01kq	244	20	be	be	VB
cord-010027-r0tl01kq	244	21	a	a	DT
cord-010027-r0tl01kq	244	22	successful	successful	JJ
cord-010027-r0tl01kq	244	23	strategy	strategy	NN
cord-010027-r0tl01kq	244	24	for	for	IN
cord-010027-r0tl01kq	244	25	identifying	identify	VBG
cord-010027-r0tl01kq	244	26	causative	causative	JJ
cord-010027-r0tl01kq	244	27	variants	variant	NNS
cord-010027-r0tl01kq	244	28	in	in	IN
cord-010027-r0tl01kq	244	29	new	new	JJ
cord-010027-r0tl01kq	244	30	genes	gene	NNS
cord-010027-r0tl01kq	244	31	as	as	RB
cord-010027-r0tl01kq	244	32	well	well	RB
cord-010027-r0tl01kq	244	33	as	as	IN
cord-010027-r0tl01kq	244	34	in	in	IN
cord-010027-r0tl01kq	244	35	known	know	VBN
cord-010027-r0tl01kq	244	36	genes	gene	NNS
cord-010027-r0tl01kq	244	37	.	.	.
cord-010027-r0tl01kq	245	1	In	in	IN
cord-010027-r0tl01kq	245	2	fact	fact	NN
cord-010027-r0tl01kq	245	3	,	,	,
cord-010027-r0tl01kq	245	4	exome	exome	NN
cord-010027-r0tl01kq	245	5	sequencing	sequencing	NN
cord-010027-r0tl01kq	245	6	has	have	VBZ
cord-010027-r0tl01kq	245	7	significantly	significantly	RB
cord-010027-r0tl01kq	245	8	expanded	expand	VBN
cord-010027-r0tl01kq	245	9	both	both	CC
cord-010027-r0tl01kq	245	10	the	the	DT
cord-010027-r0tl01kq	245	11	clinical	clinical	JJ
cord-010027-r0tl01kq	245	12	and	and	CC
cord-010027-r0tl01kq	245	13	the	the	DT
cord-010027-r0tl01kq	245	14	histological	histological	JJ
cord-010027-r0tl01kq	245	15	phenotypic	phenotypic	JJ
cord-010027-r0tl01kq	245	16	spectra	spectrum	NNS
cord-010027-r0tl01kq	245	17	of	of	IN
cord-010027-r0tl01kq	245	18	muscle	muscle	NN
cord-010027-r0tl01kq	245	19	conditions	condition	NNS
cord-010027-r0tl01kq	245	20	associated	associate	VBN
cord-010027-r0tl01kq	245	21	with	with	IN
cord-010027-r0tl01kq	245	22	causative	causative	JJ
cord-010027-r0tl01kq	245	23	variants	variant	NNS
cord-010027-r0tl01kq	245	24	in	in	IN
cord-010027-r0tl01kq	245	25	known	know	VBN
cord-010027-r0tl01kq	245	26	genes	gene	NNS
cord-010027-r0tl01kq	245	27	.	.	.
cord-010027-r0tl01kq	246	1	In	in	IN
cord-010027-r0tl01kq	246	2	the	the	DT
cord-010027-r0tl01kq	246	3	absence	absence	NN
cord-010027-r0tl01kq	246	4	of	of	IN
cord-010027-r0tl01kq	246	5	careful	careful	JJ
cord-010027-r0tl01kq	246	6	phenotyping	phenotyping	NN
cord-010027-r0tl01kq	246	7	or	or	CC
cord-010027-r0tl01kq	246	8	large	large	JJ
cord-010027-r0tl01kq	246	9	genetic	genetic	JJ
cord-010027-r0tl01kq	246	10	reference	reference	NN
cord-010027-r0tl01kq	246	11	data	data	NN
cord-010027-r0tl01kq	246	12	sets	set	NNS
cord-010027-r0tl01kq	246	13	for	for	IN
cord-010027-r0tl01kq	246	14	identifying	identify	VBG
cord-010027-r0tl01kq	246	15	variants	variant	NNS
cord-010027-r0tl01kq	246	16	of	of	IN
cord-010027-r0tl01kq	246	17	interest	interest	NN
cord-010027-r0tl01kq	246	18	,	,	,
cord-010027-r0tl01kq	246	19	causative	causative	JJ
cord-010027-r0tl01kq	246	20	variants	variant	NNS
cord-010027-r0tl01kq	246	21	may	may	MD
cord-010027-r0tl01kq	246	22	be	be	VB
cord-010027-r0tl01kq	246	23	missed	miss	VBN
cord-010027-r0tl01kq	246	24	,	,	,
cord-010027-r0tl01kq	246	25	however	however	RB
cord-010027-r0tl01kq	246	26	.	.	.
cord-010027-r0tl01kq	247	1	The	the	DT
cord-010027-r0tl01kq	247	2	use	use	NN
cord-010027-r0tl01kq	247	3	of	of	IN
cord-010027-r0tl01kq	247	4	RNA	RNA	NNP
cord-010027-r0tl01kq	247	5	sequencing	sequencing	NN
cord-010027-r0tl01kq	247	6	-	-	HYPH
cord-010027-r0tl01kq	247	7	using	use	VBG
cord-010027-r0tl01kq	247	8	RNA	RNA	NNP
cord-010027-r0tl01kq	247	9	extracted	extract	VBN
cord-010027-r0tl01kq	247	10	from	from	IN
cord-010027-r0tl01kq	247	11	muscle	muscle	NN
cord-010027-r0tl01kq	247	12	biopsy	biopsy	NN
cord-010027-r0tl01kq	247	13	specimens	specimen	NNS
cord-010027-r0tl01kq	247	14	-	-	,
cord-010027-r0tl01kq	247	15	has	have	VBZ
cord-010027-r0tl01kq	247	16	proven	prove	VBN
cord-010027-r0tl01kq	247	17	to	to	TO
cord-010027-r0tl01kq	247	18	be	be	VB
cord-010027-r0tl01kq	247	19	a	a	DT
cord-010027-r0tl01kq	247	20	powerful	powerful	JJ
cord-010027-r0tl01kq	247	21	tool	tool	NN
cord-010027-r0tl01kq	247	22	for	for	IN
cord-010027-r0tl01kq	247	23	finding	find	VBG
cord-010027-r0tl01kq	247	24	causative	causative	JJ
cord-010027-r0tl01kq	247	25	variants	variant	NNS
cord-010027-r0tl01kq	247	26	affecting	affect	VBG
cord-010027-r0tl01kq	247	27	gene	gene	NN
cord-010027-r0tl01kq	247	28	splicing	splicing	NN
cord-010027-r0tl01kq	247	29	or	or	CC
cord-010027-r0tl01kq	247	30	expression	expression	NN
cord-010027-r0tl01kq	247	31	,	,	,
cord-010027-r0tl01kq	247	32	which	which	WDT
cord-010027-r0tl01kq	247	33	may	may	MD
cord-010027-r0tl01kq	247	34	be	be	VB
cord-010027-r0tl01kq	247	35	missed	miss	VBN
cord-010027-r0tl01kq	247	36	with	with	IN
cord-010027-r0tl01kq	247	37	next	next	JJ
cord-010027-r0tl01kq	247	38	generation	generation	NN
cord-010027-r0tl01kq	247	39	sequencing	sequencing	NN
cord-010027-r0tl01kq	247	40	.	.	.
cord-010027-r0tl01kq	248	1	Muscle	muscle	NN
cord-010027-r0tl01kq	248	2	pathology	pathology	NN
cord-010027-r0tl01kq	248	3	plays	play	VBZ
cord-010027-r0tl01kq	248	4	an	an	DT
cord-010027-r0tl01kq	248	5	essential	essential	JJ
cord-010027-r0tl01kq	248	6	role	role	NN
cord-010027-r0tl01kq	248	7	in	in	IN
cord-010027-r0tl01kq	248	8	complementing	complement	VBG
cord-010027-r0tl01kq	248	9	next	next	JJ
cord-010027-r0tl01kq	248	10	generation	generation	NN
cord-010027-r0tl01kq	248	11	sequencing	sequencing	NN
cord-010027-r0tl01kq	248	12	.	.	.
cord-010027-r0tl01kq	249	1	The	the	DT
cord-010027-r0tl01kq	249	2	deep	deep	JJ
cord-010027-r0tl01kq	249	3	phenotyping	phenotyping	NN
cord-010027-r0tl01kq	249	4	of	of	IN
cord-010027-r0tl01kq	249	5	patients	patient	NNS
cord-010027-r0tl01kq	249	6	with	with	IN
cord-010027-r0tl01kq	249	7	muscle	muscle	NN
cord-010027-r0tl01kq	249	8	disease	disease	NN
cord-010027-r0tl01kq	249	9	relies	rely	VBZ
cord-010027-r0tl01kq	249	10	heavily	heavily	RB
cord-010027-r0tl01kq	249	11	on	on	IN
cord-010027-r0tl01kq	249	12	muscle	muscle	NN
cord-010027-r0tl01kq	249	13	histological	histological	JJ
cord-010027-r0tl01kq	249	14	and	and	CC
cord-010027-r0tl01kq	249	15	immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	249	16	findings	finding	NNS
cord-010027-r0tl01kq	249	17	in	in	IN
cord-010027-r0tl01kq	249	18	combination	combination	NN
cord-010027-r0tl01kq	249	19	with	with	IN
cord-010027-r0tl01kq	249	20	muscle	muscle	NN
cord-010027-r0tl01kq	249	21	imaging	imaging	NN
cord-010027-r0tl01kq	249	22	,	,	,
cord-010027-r0tl01kq	249	23	clinical	clinical	JJ
cord-010027-r0tl01kq	249	24	history	history	NN
cord-010027-r0tl01kq	249	25	and	and	CC
cord-010027-r0tl01kq	249	26	neuromuscular	neuromuscular	JJ
cord-010027-r0tl01kq	249	27	examination	examination	NN
cord-010027-r0tl01kq	249	28	findings	finding	NNS
cord-010027-r0tl01kq	249	29	.	.	.
cord-010027-r0tl01kq	250	1	Examples	example	NNS
cord-010027-r0tl01kq	250	2	of	of	IN
cord-010027-r0tl01kq	250	3	how	how	WRB
cord-010027-r0tl01kq	250	4	next	next	JJ
cord-010027-r0tl01kq	250	5	generation	generation	NN
cord-010027-r0tl01kq	250	6	sequencing	sequencing	NN
cord-010027-r0tl01kq	250	7	coupled	couple	VBN
cord-010027-r0tl01kq	250	8	with	with	IN
cord-010027-r0tl01kq	250	9	careful	careful	JJ
cord-010027-r0tl01kq	250	10	clinical	clinical	JJ
cord-010027-r0tl01kq	250	11	and	and	CC
cord-010027-r0tl01kq	250	12	histological	histological	JJ
cord-010027-r0tl01kq	250	13	phenotyping	phenotyping	NN
cord-010027-r0tl01kq	250	14	has	have	VBZ
cord-010027-r0tl01kq	250	15	uncovered	uncover	VBN
cord-010027-r0tl01kq	250	16	causative	causative	JJ
cord-010027-r0tl01kq	250	17	variants	variant	NNS
cord-010027-r0tl01kq	250	18	in	in	IN
cord-010027-r0tl01kq	250	19	new	new	JJ
cord-010027-r0tl01kq	250	20	genes	gene	NNS
cord-010027-r0tl01kq	250	21	as	as	RB
cord-010027-r0tl01kq	250	22	well	well	RB
cord-010027-r0tl01kq	250	23	as	as	IN
cord-010027-r0tl01kq	250	24	in	in	IN
cord-010027-r0tl01kq	250	25	known	know	VBN
cord-010027-r0tl01kq	250	26	genes	gene	NNS
cord-010027-r0tl01kq	250	27	will	will	MD
cord-010027-r0tl01kq	250	28	be	be	VB
cord-010027-r0tl01kq	250	29	discussed	discuss	VBN
cord-010027-r0tl01kq	250	30	in	in	IN
cord-010027-r0tl01kq	250	31	this	this	DT
cord-010027-r0tl01kq	250	32	talk	talk	NN
cord-010027-r0tl01kq	250	33	.	.	.
cord-010027-r0tl01kq	251	1	Medicine	medicine	NN
cord-010027-r0tl01kq	251	2	,	,	,
cord-010027-r0tl01kq	251	3	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	251	4	pathology	pathology	NN
cord-010027-r0tl01kq	251	5	,	,	,
cord-010027-r0tl01kq	251	6	technology	technology	NN
cord-010027-r0tl01kq	251	7	,	,	,
cord-010027-r0tl01kq	251	8	and	and	CC
cord-010027-r0tl01kq	251	9	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	251	10	tests	test	NNS
cord-010027-r0tl01kq	251	11	are	be	VBP
cord-010027-r0tl01kq	251	12	evolving	evolve	VBG
cord-010027-r0tl01kq	251	13	at	at	IN
cord-010027-r0tl01kq	251	14	an	an	DT
cord-010027-r0tl01kq	251	15	extremely	extremely	RB
cord-010027-r0tl01kq	251	16	rapid	rapid	JJ
cord-010027-r0tl01kq	251	17	pace	pace	NN
cord-010027-r0tl01kq	251	18	.	.	.
cord-010027-r0tl01kq	252	1	Drug	drug	NN
cord-010027-r0tl01kq	252	2	developers	developer	NNS
cord-010027-r0tl01kq	252	3	and	and	CC
cord-010027-r0tl01kq	252	4	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	252	5	developers	developer	NNS
cord-010027-r0tl01kq	252	6	each	each	DT
cord-010027-r0tl01kq	252	7	face	face	VBP
cord-010027-r0tl01kq	252	8	unique	unique	JJ
cord-010027-r0tl01kq	252	9	challenges	challenge	NNS
cord-010027-r0tl01kq	252	10	.	.	.
cord-010027-r0tl01kq	253	1	Companion	companion	NN
cord-010027-r0tl01kq	253	2	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	253	3	development	development	NN
cord-010027-r0tl01kq	253	4	is	be	VBZ
cord-010027-r0tl01kq	253	5	a	a	DT
cord-010027-r0tl01kq	253	6	key	key	JJ
cord-010027-r0tl01kq	253	7	component	component	NN
cord-010027-r0tl01kq	253	8	of	of	IN
cord-010027-r0tl01kq	253	9	pharma	pharma	NNP
cord-010027-r0tl01kq	253	10	drug	drug	NNP
cord-010027-r0tl01kq	253	11	development	development	NNP
cord-010027-r0tl01kq	253	12	strategy	strategy	NN
cord-010027-r0tl01kq	253	13	.	.	.
cord-010027-r0tl01kq	254	1	We	-PRON-	PRP
cord-010027-r0tl01kq	254	2	will	will	MD
cord-010027-r0tl01kq	254	3	discuss	discuss	VB
cord-010027-r0tl01kq	254	4	the	the	DT
cord-010027-r0tl01kq	254	5	importance	importance	NN
cord-010027-r0tl01kq	254	6	of	of	IN
cord-010027-r0tl01kq	254	7	companion	companion	NN
cord-010027-r0tl01kq	254	8	diagnostics	diagnostic	NNS
cord-010027-r0tl01kq	254	9	in	in	IN
cord-010027-r0tl01kq	254	10	the	the	DT
cord-010027-r0tl01kq	254	11	success	success	NN
cord-010027-r0tl01kq	254	12	of	of	IN
cord-010027-r0tl01kq	254	13	personalized	personalized	JJ
cord-010027-r0tl01kq	254	14	medicine	medicine	NN
cord-010027-r0tl01kq	254	15	,	,	,
cord-010027-r0tl01kq	254	16	the	the	DT
cord-010027-r0tl01kq	254	17	FDA	FDA	NNP
cord-010027-r0tl01kq	254	18	position	position	NN
cord-010027-r0tl01kq	254	19	on	on	IN
cord-010027-r0tl01kq	254	20	companion	companion	NN
cord-010027-r0tl01kq	254	21	diagnostics	diagnostic	NNS
cord-010027-r0tl01kq	254	22	,	,	,
cord-010027-r0tl01kq	254	23	and	and	CC
cord-010027-r0tl01kq	254	24	the	the	DT
cord-010027-r0tl01kq	254	25	role	role	NN
cord-010027-r0tl01kq	254	26	,	,	,
cord-010027-r0tl01kq	254	27	advantages	advantage	NNS
cord-010027-r0tl01kq	254	28	and	and	CC
cord-010027-r0tl01kq	254	29	disadvantages	disadvantage	NNS
cord-010027-r0tl01kq	254	30	of	of	IN
cord-010027-r0tl01kq	254	31	tissue	tissue	NN
cord-010027-r0tl01kq	254	32	based	base	VBN
cord-010027-r0tl01kq	254	33	companion	companion	NN
cord-010027-r0tl01kq	254	34	diagnostics	diagnostic	NNS
cord-010027-r0tl01kq	254	35	.	.	.
cord-010027-r0tl01kq	255	1	Other	other	JJ
cord-010027-r0tl01kq	255	2	technologies	technology	NNS
cord-010027-r0tl01kq	255	3	,	,	,
cord-010027-r0tl01kq	255	4	such	such	JJ
cord-010027-r0tl01kq	255	5	as	as	IN
cord-010027-r0tl01kq	255	6	Next	Next	NNP
cord-010027-r0tl01kq	255	7	Gen	Gen	NNP
cord-010027-r0tl01kq	255	8	Sequencing	Sequencing	NNP
cord-010027-r0tl01kq	255	9	,	,	,
cord-010027-r0tl01kq	255	10	will	will	MD
cord-010027-r0tl01kq	255	11	increasingly	increasingly	RB
cord-010027-r0tl01kq	255	12	be	be	VB
cord-010027-r0tl01kq	255	13	utilized	utilize	VBN
cord-010027-r0tl01kq	255	14	in	in	IN
cord-010027-r0tl01kq	255	15	a	a	DT
cord-010027-r0tl01kq	255	16	complementary	complementary	JJ
cord-010027-r0tl01kq	255	17	fashion	fashion	NN
cord-010027-r0tl01kq	255	18	along	along	IN
cord-010027-r0tl01kq	255	19	with	with	IN
cord-010027-r0tl01kq	255	20	traditional	traditional	JJ
cord-010027-r0tl01kq	255	21	slide	slide	NN
cord-010027-r0tl01kq	255	22	based	base	VBN
cord-010027-r0tl01kq	255	23	immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	255	24	and	and	CC
cord-010027-r0tl01kq	255	25	in	in	IN
cord-010027-r0tl01kq	255	26	situ	situ	JJ
cord-010027-r0tl01kq	255	27	hybridization	hybridization	NN
cord-010027-r0tl01kq	255	28	.	.	.
cord-010027-r0tl01kq	256	1	The	the	DT
cord-010027-r0tl01kq	256	2	scope	scope	NN
cord-010027-r0tl01kq	256	3	and	and	CC
cord-010027-r0tl01kq	256	4	limitations	limitation	NNS
cord-010027-r0tl01kq	256	5	of	of	IN
cord-010027-r0tl01kq	256	6	available	available	JJ
cord-010027-r0tl01kq	256	7	technologies	technology	NNS
cord-010027-r0tl01kq	256	8	will	will	MD
cord-010027-r0tl01kq	256	9	be	be	VB
cord-010027-r0tl01kq	256	10	reviewed	review	VBN
cord-010027-r0tl01kq	256	11	.	.	.
cord-010027-r0tl01kq	257	1	Diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	257	2	technologies	technology	NNS
cord-010027-r0tl01kq	257	3	of	of	IN
cord-010027-r0tl01kq	257	4	all	all	DT
cord-010027-r0tl01kq	257	5	types	type	NNS
cord-010027-r0tl01kq	257	6	will	will	MD
cord-010027-r0tl01kq	257	7	complement	complement	VB
cord-010027-r0tl01kq	257	8	each	each	DT
cord-010027-r0tl01kq	257	9	other	other	JJ
cord-010027-r0tl01kq	257	10	to	to	TO
cord-010027-r0tl01kq	257	11	provide	provide	VB
cord-010027-r0tl01kq	257	12	the	the	DT
cord-010027-r0tl01kq	257	13	most	most	RBS
cord-010027-r0tl01kq	257	14	accurate	accurate	JJ
cord-010027-r0tl01kq	257	15	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	257	16	information	information	NN
cord-010027-r0tl01kq	257	17	for	for	IN
cord-010027-r0tl01kq	257	18	clinicians	clinician	NNS
cord-010027-r0tl01kq	257	19	and	and	CC
cord-010027-r0tl01kq	257	20	patients	patient	NNS
cord-010027-r0tl01kq	257	21	.	.	.
cord-010027-r0tl01kq	258	1	Following	follow	VBG
cord-010027-r0tl01kq	258	2	the	the	DT
cord-010027-r0tl01kq	258	3	2008	2008	CD
cord-010027-r0tl01kq	258	4	WHO	who	WP
cord-010027-r0tl01kq	258	5	classification	classification	NN
cord-010027-r0tl01kq	258	6	of	of	IN
cord-010027-r0tl01kq	258	7	haematological	haematological	JJ
cord-010027-r0tl01kq	258	8	malignancies	malignancy	NNS
cord-010027-r0tl01kq	258	9	there	there	EX
cord-010027-r0tl01kq	258	10	has	have	VBZ
cord-010027-r0tl01kq	258	11	been	be	VBN
cord-010027-r0tl01kq	258	12	a	a	DT
cord-010027-r0tl01kq	258	13	greater	great	JJR
cord-010027-r0tl01kq	258	14	emphasis	emphasis	NN
cord-010027-r0tl01kq	258	15	on	on	IN
cord-010027-r0tl01kq	258	16	the	the	DT
cord-010027-r0tl01kq	258	17	integration	integration	NN
cord-010027-r0tl01kq	258	18	of	of	IN
cord-010027-r0tl01kq	258	19	molecular	molecular	JJ
cord-010027-r0tl01kq	258	20	information	information	NN
cord-010027-r0tl01kq	258	21	with	with	IN
cord-010027-r0tl01kq	258	22	clinical	clinical	JJ
cord-010027-r0tl01kq	258	23	and	and	CC
cord-010027-r0tl01kq	258	24	morphological	morphological	JJ
cord-010027-r0tl01kq	258	25	data	datum	NNS
cord-010027-r0tl01kq	258	26	not	not	RB
cord-010027-r0tl01kq	258	27	just	just	RB
cord-010027-r0tl01kq	258	28	for	for	IN
cord-010027-r0tl01kq	258	29	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	258	30	purposes	purpose	NNS
cord-010027-r0tl01kq	258	31	but	but	CC
cord-010027-r0tl01kq	258	32	also	also	RB
cord-010027-r0tl01kq	258	33	to	to	TO
cord-010027-r0tl01kq	258	34	help	help	VB
cord-010027-r0tl01kq	258	35	convey	convey	VB
cord-010027-r0tl01kq	258	36	both	both	DT
cord-010027-r0tl01kq	258	37	prognostic	prognostic	JJ
cord-010027-r0tl01kq	258	38	and	and	CC
cord-010027-r0tl01kq	258	39	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	258	40	information	information	NN
cord-010027-r0tl01kq	258	41	.	.	.
cord-010027-r0tl01kq	259	1	This	this	DT
cord-010027-r0tl01kq	259	2	talk	talk	NN
cord-010027-r0tl01kq	259	3	will	will	MD
cord-010027-r0tl01kq	259	4	concentrate	concentrate	VB
cord-010027-r0tl01kq	259	5	on	on	IN
cord-010027-r0tl01kq	259	6	routine	routine	JJ
cord-010027-r0tl01kq	259	7	testing	testing	NN
cord-010027-r0tl01kq	259	8	in	in	IN
cord-010027-r0tl01kq	259	9	the	the	DT
cord-010027-r0tl01kq	259	10	work	work	NN
cord-010027-r0tl01kq	259	11	-	-	HYPH
cord-010027-r0tl01kq	259	12	up	up	NN
cord-010027-r0tl01kq	259	13	of	of	IN
cord-010027-r0tl01kq	259	14	common	common	JJ
cord-010027-r0tl01kq	259	15	haematological	haematological	JJ
cord-010027-r0tl01kq	259	16	malignancies	malignancy	NNS
cord-010027-r0tl01kq	259	17	focusing	focus	VBG
cord-010027-r0tl01kq	259	18	specifically	specifically	RB
cord-010027-r0tl01kq	259	19	on	on	IN
cord-010027-r0tl01kq	259	20	clonality	clonality	NN
cord-010027-r0tl01kq	259	21	and	and	CC
cord-010027-r0tl01kq	259	22	translocation	translocation	NN
cord-010027-r0tl01kq	259	23	analysis	analysis	NN
cord-010027-r0tl01kq	259	24	in	in	IN
cord-010027-r0tl01kq	259	25	lymphoproliferations	lymphoproliferation	NNS
cord-010027-r0tl01kq	259	26	and	and	CC
cord-010027-r0tl01kq	259	27	mutational	mutational	JJ
cord-010027-r0tl01kq	259	28	testing	testing	NN
cord-010027-r0tl01kq	259	29	in	in	IN
cord-010027-r0tl01kq	259	30	BCR	BCR	NNP
cord-010027-r0tl01kq	259	31	-	-	HYPH
cord-010027-r0tl01kq	259	32	ABL	ABL	NNP
cord-010027-r0tl01kq	259	33	negative	negative	JJ
cord-010027-r0tl01kq	259	34	myeloproliferative	myeloproliferative	JJ
cord-010027-r0tl01kq	259	35	neoplasms	neoplasm	NNS
cord-010027-r0tl01kq	259	36	.	.	.
cord-010027-r0tl01kq	260	1	Using	use	VBG
cord-010027-r0tl01kq	260	2	case	case	NN
cord-010027-r0tl01kq	260	3	studies	study	NNS
cord-010027-r0tl01kq	260	4	to	to	TO
cord-010027-r0tl01kq	260	5	illustrate	illustrate	VB
cord-010027-r0tl01kq	260	6	common	common	JJ
cord-010027-r0tl01kq	260	7	indications	indication	NNS
cord-010027-r0tl01kq	260	8	for	for	IN
cord-010027-r0tl01kq	260	9	testing	test	VBG
cord-010027-r0tl01kq	260	10	this	this	DT
cord-010027-r0tl01kq	260	11	talk	talk	NN
cord-010027-r0tl01kq	260	12	will	will	MD
cord-010027-r0tl01kq	260	13	also	also	RB
cord-010027-r0tl01kq	260	14	highlight	highlight	VB
cord-010027-r0tl01kq	260	15	some	some	DT
cord-010027-r0tl01kq	260	16	of	of	IN
cord-010027-r0tl01kq	260	17	the	the	DT
cord-010027-r0tl01kq	260	18	practical	practical	JJ
cord-010027-r0tl01kq	260	19	points	point	NNS
cord-010027-r0tl01kq	260	20	and	and	CC
cord-010027-r0tl01kq	260	21	pitfalls	pitfall	NNS
cord-010027-r0tl01kq	260	22	in	in	IN
cord-010027-r0tl01kq	260	23	the	the	DT
cord-010027-r0tl01kq	260	24	interpretation	interpretation	NN
cord-010027-r0tl01kq	260	25	of	of	IN
cord-010027-r0tl01kq	260	26	these	these	DT
cord-010027-r0tl01kq	260	27	tests	test	NNS
cord-010027-r0tl01kq	260	28	.	.	.
cord-010027-r0tl01kq	261	1	Beaumont	Beaumont	NNP
cord-010027-r0tl01kq	261	2	Hospital	Hospital	NNP
cord-010027-r0tl01kq	261	3	,	,	,
cord-010027-r0tl01kq	261	4	Dublin	Dublin	NNP
cord-010027-r0tl01kq	261	5	,	,	,
cord-010027-r0tl01kq	261	6	Ireland	Ireland	NNP
cord-010027-r0tl01kq	261	7	"	"	''
cord-010027-r0tl01kq	262	1	Should	Should	MD
cord-010027-r0tl01kq	262	2	I	-PRON-	PRP
cord-010027-r0tl01kq	262	3	keep	keep	VB
cord-010027-r0tl01kq	262	4	the	the	DT
cord-010027-r0tl01kq	262	5	brain	brain	NN
cord-010027-r0tl01kq	262	6	?	?	.
cord-010027-r0tl01kq	263	1	"	"	``
cord-010027-r0tl01kq	263	2	is	be	VBZ
cord-010027-r0tl01kq	263	3	one	one	CD
cord-010027-r0tl01kq	263	4	of	of	IN
cord-010027-r0tl01kq	263	5	the	the	DT
cord-010027-r0tl01kq	263	6	most	most	RBS
cord-010027-r0tl01kq	263	7	frequent	frequent	JJ
cord-010027-r0tl01kq	263	8	questions	question	NNS
cord-010027-r0tl01kq	263	9	addressed	address	VBN
cord-010027-r0tl01kq	263	10	to	to	IN
cord-010027-r0tl01kq	263	11	neuropathologists	neuropathologist	NNS
cord-010027-r0tl01kq	263	12	by	by	IN
cord-010027-r0tl01kq	263	13	surgical	surgical	JJ
cord-010027-r0tl01kq	263	14	pathology	pathology	NN
cord-010027-r0tl01kq	263	15	colleagues	colleague	NNS
cord-010027-r0tl01kq	263	16	.	.	.
cord-010027-r0tl01kq	264	1	Fears	fear	NNS
cord-010027-r0tl01kq	264	2	relating	relate	VBG
cord-010027-r0tl01kq	264	3	to	to	IN
cord-010027-r0tl01kq	264	4	inappropriate	inappropriate	JJ
cord-010027-r0tl01kq	264	5	organ	organ	NN
cord-010027-r0tl01kq	264	6	retention	retention	NN
cord-010027-r0tl01kq	264	7	coupled	couple	VBN
cord-010027-r0tl01kq	264	8	with	with	IN
cord-010027-r0tl01kq	264	9	decreasing	decrease	VBG
cord-010027-r0tl01kq	264	10	availability	availability	NN
cord-010027-r0tl01kq	264	11	of	of	IN
cord-010027-r0tl01kq	264	12	expert	expert	JJ
cord-010027-r0tl01kq	264	13	neuropathology	neuropathology	NN
cord-010027-r0tl01kq	264	14	opinion	opinion	NN
cord-010027-r0tl01kq	264	15	and	and	CC
cord-010027-r0tl01kq	264	16	the	the	DT
cord-010027-r0tl01kq	264	17	widely	widely	RB
cord-010027-r0tl01kq	264	18	held	held	JJ
cord-010027-r0tl01kq	264	19	belief	belief	NN
cord-010027-r0tl01kq	264	20	that	that	IN
cord-010027-r0tl01kq	264	21	advances	advance	VBZ
cord-010027-r0tl01kq	264	22	in	in	IN
cord-010027-r0tl01kq	264	23	neuroimaging	neuroimaging	NN
cord-010027-r0tl01kq	264	24	have	have	VBP
cord-010027-r0tl01kq	264	25	replaced	replace	VBN
cord-010027-r0tl01kq	264	26	the	the	DT
cord-010027-r0tl01kq	264	27	brain	brain	NN
cord-010027-r0tl01kq	264	28	autopsy	autopsy	NN
cord-010027-r0tl01kq	264	29	,	,	,
cord-010027-r0tl01kq	264	30	have	have	VBP
cord-010027-r0tl01kq	264	31	all	all	DT
cord-010027-r0tl01kq	264	32	contributed	contribute	VBN
cord-010027-r0tl01kq	264	33	to	to	IN
cord-010027-r0tl01kq	264	34	a	a	DT
cord-010027-r0tl01kq	264	35	decline	decline	NN
cord-010027-r0tl01kq	264	36	in	in	IN
cord-010027-r0tl01kq	264	37	the	the	DT
cord-010027-r0tl01kq	264	38	post	post	AFX
cord-010027-r0tl01kq	264	39	mortem	mortem	NN
cord-010027-r0tl01kq	264	40	study	study	NN
cord-010027-r0tl01kq	264	41	of	of	IN
cord-010027-r0tl01kq	264	42	human	human	JJ
cord-010027-r0tl01kq	264	43	brain	brain	NN
cord-010027-r0tl01kq	264	44	tissue	tissue	NN
cord-010027-r0tl01kq	264	45	.	.	.
cord-010027-r0tl01kq	265	1	Leaving	leave	VBG
cord-010027-r0tl01kq	265	2	aside	aside	RB
cord-010027-r0tl01kq	265	3	the	the	DT
cord-010027-r0tl01kq	265	4	critical	critical	JJ
cord-010027-r0tl01kq	265	5	relevance	relevance	NN
cord-010027-r0tl01kq	265	6	of	of	IN
cord-010027-r0tl01kq	265	7	neuropathology	neuropathology	NN
cord-010027-r0tl01kq	265	8	to	to	IN
cord-010027-r0tl01kq	265	9	forensic	forensic	JJ
cord-010027-r0tl01kq	265	10	medicine	medicine	NN
cord-010027-r0tl01kq	265	11	,	,	,
cord-010027-r0tl01kq	265	12	the	the	DT
cord-010027-r0tl01kq	265	13	vital	vital	JJ
cord-010027-r0tl01kq	265	14	role	role	NN
cord-010027-r0tl01kq	265	15	played	play	VBN
cord-010027-r0tl01kq	265	16	by	by	IN
cord-010027-r0tl01kq	265	17	careful	careful	JJ
cord-010027-r0tl01kq	265	18	examination	examination	NN
cord-010027-r0tl01kq	265	19	of	of	IN
cord-010027-r0tl01kq	265	20	the	the	DT
cord-010027-r0tl01kq	265	21	post	post	FW
cord-010027-r0tl01kq	265	22	mortem	mortem	NN
cord-010027-r0tl01kq	265	23	brain	brain	NN
cord-010027-r0tl01kq	265	24	extends	extend	VBZ
cord-010027-r0tl01kq	265	25	far	far	RB
cord-010027-r0tl01kq	265	26	beyond	beyond	IN
cord-010027-r0tl01kq	265	27	pathology	pathology	NN
cord-010027-r0tl01kq	265	28	and	and	CC
cord-010027-r0tl01kq	265	29	has	have	VBZ
cord-010027-r0tl01kq	265	30	contributed	contribute	VBN
cord-010027-r0tl01kq	265	31	greatly	greatly	RB
cord-010027-r0tl01kq	265	32	to	to	IN
cord-010027-r0tl01kq	265	33	science	science	NN
cord-010027-r0tl01kq	265	34	and	and	CC
cord-010027-r0tl01kq	265	35	medicine	medicine	NN
cord-010027-r0tl01kq	265	36	.	.	.
cord-010027-r0tl01kq	266	1	In	in	IN
cord-010027-r0tl01kq	266	2	general	general	JJ
cord-010027-r0tl01kq	266	3	,	,	,
cord-010027-r0tl01kq	266	4	prolonged	prolonged	JJ
cord-010027-r0tl01kq	266	5	retention	retention	NN
cord-010027-r0tl01kq	266	6	of	of	IN
cord-010027-r0tl01kq	266	7	entire	entire	JJ
cord-010027-r0tl01kq	266	8	brains	brain	NNS
cord-010027-r0tl01kq	266	9	may	may	MD
cord-010027-r0tl01kq	266	10	be	be	VB
cord-010027-r0tl01kq	266	11	avoided	avoid	VBN
cord-010027-r0tl01kq	266	12	.	.	.
cord-010027-r0tl01kq	267	1	In	in	IN
cord-010027-r0tl01kq	267	2	hospital	hospital	NN
cord-010027-r0tl01kq	267	3	practice	practice	NN
cord-010027-r0tl01kq	267	4	it	-PRON-	PRP
cord-010027-r0tl01kq	267	5	is	be	VBZ
cord-010027-r0tl01kq	267	6	uncommon	uncommon	JJ
cord-010027-r0tl01kq	267	7	for	for	IN
cord-010027-r0tl01kq	267	8	a	a	DT
cord-010027-r0tl01kq	267	9	patient	patient	NN
cord-010027-r0tl01kq	267	10	to	to	TO
cord-010027-r0tl01kq	267	11	die	die	VB
cord-010027-r0tl01kq	267	12	without	without	IN
cord-010027-r0tl01kq	267	13	brain	brain	NN
cord-010027-r0tl01kq	267	14	imaging	imaging	NN
cord-010027-r0tl01kq	267	15	.	.	.
cord-010027-r0tl01kq	268	1	Access	access	NN
cord-010027-r0tl01kq	268	2	to	to	IN
cord-010027-r0tl01kq	268	3	pre	pre	JJ
cord-010027-r0tl01kq	268	4	-	-	JJ
cord-010027-r0tl01kq	268	5	mortem	mortem	JJ
cord-010027-r0tl01kq	268	6	brain	brain	NN
cord-010027-r0tl01kq	268	7	imaging	imaging	NN
cord-010027-r0tl01kq	268	8	will	will	MD
cord-010027-r0tl01kq	268	9	guide	guide	VB
cord-010027-r0tl01kq	268	10	the	the	DT
cord-010027-r0tl01kq	268	11	surgical	surgical	JJ
cord-010027-r0tl01kq	268	12	pathologist	pathologist	NN
cord-010027-r0tl01kq	268	13	in	in	IN
cord-010027-r0tl01kq	268	14	careful	careful	JJ
cord-010027-r0tl01kq	268	15	and	and	CC
cord-010027-r0tl01kq	268	16	appropriate	appropriate	JJ
cord-010027-r0tl01kq	268	17	sampling	sampling	NN
cord-010027-r0tl01kq	268	18	of	of	IN
cord-010027-r0tl01kq	268	19	calvarial	calvarial	NN
cord-010027-r0tl01kq	268	20	,	,	,
cord-010027-r0tl01kq	268	21	dural	dural	NN
cord-010027-r0tl01kq	268	22	,	,	,
cord-010027-r0tl01kq	268	23	meningeal	meningeal	JJ
cord-010027-r0tl01kq	268	24	,	,	,
cord-010027-r0tl01kq	268	25	vascular	vascular	JJ
cord-010027-r0tl01kq	268	26	and	and	CC
cord-010027-r0tl01kq	268	27	parenchymal	parenchymal	JJ
cord-010027-r0tl01kq	268	28	central	central	JJ
cord-010027-r0tl01kq	268	29	nervous	nervous	JJ
cord-010027-r0tl01kq	268	30	system	system	NN
cord-010027-r0tl01kq	268	31	components	component	NNS
cord-010027-r0tl01kq	268	32	.	.	.
cord-010027-r0tl01kq	269	1	Spinal	spinal	JJ
cord-010027-r0tl01kq	269	2	cord	cord	NN
cord-010027-r0tl01kq	269	3	examination	examination	NN
cord-010027-r0tl01kq	269	4	requires	require	VBZ
cord-010027-r0tl01kq	269	5	prior	prior	JJ
cord-010027-r0tl01kq	269	6	experience	experience	NN
cord-010027-r0tl01kq	269	7	in	in	IN
cord-010027-r0tl01kq	269	8	spinal	spinal	JJ
cord-010027-r0tl01kq	269	9	cord	cord	NN
cord-010027-r0tl01kq	269	10	removal	removal	NN
cord-010027-r0tl01kq	269	11	but	but	CC
cord-010027-r0tl01kq	269	12	most	most	JJS
cord-010027-r0tl01kq	269	13	post	post	NN
cord-010027-r0tl01kq	269	14	mortem	mortem	NN
cord-010027-r0tl01kq	269	15	technologists	technologist	NNS
cord-010027-r0tl01kq	269	16	are	be	VBP
cord-010027-r0tl01kq	269	17	expert	expert	JJ
cord-010027-r0tl01kq	269	18	in	in	IN
cord-010027-r0tl01kq	269	19	cord	cord	NN
cord-010027-r0tl01kq	269	20	extraction	extraction	NN
cord-010027-r0tl01kq	269	21	.	.	.
cord-010027-r0tl01kq	270	1	Sampling	sampling	NN
cord-010027-r0tl01kq	270	2	and	and	CC
cord-010027-r0tl01kq	270	3	appropriate	appropriate	JJ
cord-010027-r0tl01kq	270	4	processing	processing	NN
cord-010027-r0tl01kq	270	5	of	of	IN
cord-010027-r0tl01kq	270	6	nerve	nerve	NN
cord-010027-r0tl01kq	270	7	and	and	CC
cord-010027-r0tl01kq	270	8	muscle	muscle	NN
cord-010027-r0tl01kq	270	9	requires	require	VBZ
cord-010027-r0tl01kq	270	10	prior	prior	JJ
cord-010027-r0tl01kq	270	11	experience	experience	NN
cord-010027-r0tl01kq	270	12	or	or	CC
cord-010027-r0tl01kq	270	13	neuropathology	neuropathology	NN
cord-010027-r0tl01kq	270	14	advice	advice	NN
cord-010027-r0tl01kq	270	15	.	.	.
cord-010027-r0tl01kq	271	1	High	high	JJ
cord-010027-r0tl01kq	271	2	quality	quality	NN
cord-010027-r0tl01kq	271	3	photography	photography	NN
cord-010027-r0tl01kq	271	4	obtained	obtain	VBN
cord-010027-r0tl01kq	271	5	at	at	IN
cord-010027-r0tl01kq	271	6	all	all	DT
cord-010027-r0tl01kq	271	7	phases	phase	NNS
cord-010027-r0tl01kq	271	8	of	of	IN
cord-010027-r0tl01kq	271	9	post	post	FW
cord-010027-r0tl01kq	271	10	mortem	mortem	NN
cord-010027-r0tl01kq	271	11	brain	brain	NN
cord-010027-r0tl01kq	271	12	examination	examination	NN
cord-010027-r0tl01kq	271	13	including	include	VBG
cord-010027-r0tl01kq	271	14	the	the	DT
cord-010027-r0tl01kq	271	15	coronally	coronally	RB
cord-010027-r0tl01kq	271	16	sectioned	section	VBN
cord-010027-r0tl01kq	271	17	individual	individual	JJ
cord-010027-r0tl01kq	271	18	cerebral	cerebral	JJ
cord-010027-r0tl01kq	271	19	hemispheres	hemisphere	NNS
cord-010027-r0tl01kq	271	20	,	,	,
cord-010027-r0tl01kq	271	21	with	with	IN
cord-010027-r0tl01kq	271	22	retention	retention	NN
cord-010027-r0tl01kq	271	23	of	of	IN
cord-010027-r0tl01kq	271	24	blocks	block	NNS
cord-010027-r0tl01kq	271	25	from	from	IN
cord-010027-r0tl01kq	271	26	each	each	DT
cord-010027-r0tl01kq	271	27	of	of	IN
cord-010027-r0tl01kq	271	28	the	the	DT
cord-010027-r0tl01kq	271	29	brain	brain	NN
cord-010027-r0tl01kq	271	30	lobes	lob	VBZ
cord-010027-r0tl01kq	271	31	together	together	RB
cord-010027-r0tl01kq	271	32	with	with	IN
cord-010027-r0tl01kq	271	33	cerebellum	cerebellum	NN
cord-010027-r0tl01kq	271	34	,	,	,
cord-010027-r0tl01kq	271	35	brain	brain	NN
cord-010027-r0tl01kq	271	36	stem	stem	NN
cord-010027-r0tl01kq	271	37	,	,	,
cord-010027-r0tl01kq	271	38	vessels	vessel	NNS
cord-010027-r0tl01kq	271	39	and	and	CC
cord-010027-r0tl01kq	271	40	dura	dura	NN
cord-010027-r0tl01kq	271	41	-meninges	-meninge	NNS
cord-010027-r0tl01kq	271	42	will	will	MD
cord-010027-r0tl01kq	271	43	ensure	ensure	VB
cord-010027-r0tl01kq	271	44	that	that	IN
cord-010027-r0tl01kq	271	45	in	in	IN
cord-010027-r0tl01kq	271	46	the	the	DT
cord-010027-r0tl01kq	271	47	event	event	NN
cord-010027-r0tl01kq	271	48	of	of	IN
cord-010027-r0tl01kq	271	49	a	a	DT
cord-010027-r0tl01kq	271	50	neuropathology	neuropathology	NN
cord-010027-r0tl01kq	271	51	opinion	opinion	NN
cord-010027-r0tl01kq	271	52	benign	benign	JJ
cord-010027-r0tl01kq	271	53	required	require	VBN
cord-010027-r0tl01kq	271	54	-that	-that	NN
cord-010027-r0tl01kq	271	55	opinion	opinion	NN
cord-010027-r0tl01kq	271	56	will	will	MD
cord-010027-r0tl01kq	271	57	not	not	RB
cord-010027-r0tl01kq	271	58	be	be	VB
cord-010027-r0tl01kq	271	59	compromised	compromise	VBN
cord-010027-r0tl01kq	271	60	.	.	.
cord-010027-r0tl01kq	272	1	Specific	specific	JJ
cord-010027-r0tl01kq	272	2	issues	issue	NNS
cord-010027-r0tl01kq	272	3	which	which	WDT
cord-010027-r0tl01kq	272	4	will	will	MD
cord-010027-r0tl01kq	272	5	be	be	VB
cord-010027-r0tl01kq	272	6	addressed	address	VBN
cord-010027-r0tl01kq	272	7	will	will	MD
cord-010027-r0tl01kq	272	8	include	include	VB
cord-010027-r0tl01kq	272	9	the	the	DT
cord-010027-r0tl01kq	272	10	death	death	NN
cord-010027-r0tl01kq	272	11	of	of	IN
cord-010027-r0tl01kq	272	12	patients	patient	NNS
cord-010027-r0tl01kq	272	13	with	with	IN
cord-010027-r0tl01kq	272	14	epilepsy	epilepsy	NN
cord-010027-r0tl01kq	272	15	,	,	,
cord-010027-r0tl01kq	272	16	dementia	dementia	NN
cord-010027-r0tl01kq	272	17	,	,	,
cord-010027-r0tl01kq	272	18	stroke	stroke	NN
cord-010027-r0tl01kq	272	19	and	and	CC
cord-010027-r0tl01kq	272	20	undiagnosed	undiagnosed	JJ
cord-010027-r0tl01kq	272	21	neurological	neurological	JJ
cord-010027-r0tl01kq	272	22	disease	disease	NN
cord-010027-r0tl01kq	272	23	.	.	.
cord-010027-r0tl01kq	273	1	The	the	DT
cord-010027-r0tl01kq	273	2	key	key	JJ
cord-010027-r0tl01kq	273	3	learning	learn	VBG
cord-010027-r0tl01kq	273	4	objective	objective	NN
cord-010027-r0tl01kq	273	5	will	will	MD
cord-010027-r0tl01kq	273	6	be	be	VB
cord-010027-r0tl01kq	273	7	to	to	TO
cord-010027-r0tl01kq	273	8	ensure	ensure	VB
cord-010027-r0tl01kq	273	9	that	that	IN
cord-010027-r0tl01kq	273	10	pathology	pathology	NN
cord-010027-r0tl01kq	273	11	trainees	trainee	NNS
cord-010027-r0tl01kq	273	12	approach	approach	VBP
cord-010027-r0tl01kq	273	13	post	post	AFX
cord-010027-r0tl01kq	273	14	mortem	mortem	NN
cord-010027-r0tl01kq	273	15	examination	examination	NN
cord-010027-r0tl01kq	273	16	of	of	IN
cord-010027-r0tl01kq	273	17	the	the	DT
cord-010027-r0tl01kq	273	18	nervous	nervous	JJ
cord-010027-r0tl01kq	273	19	system	system	NN
cord-010027-r0tl01kq	273	20	with	with	IN
cord-010027-r0tl01kq	273	21	interest	interest	NN
cord-010027-r0tl01kq	273	22	and	and	CC
cord-010027-r0tl01kq	273	23	excitement	excitement	NN
cord-010027-r0tl01kq	273	24	.	.	.
cord-010027-r0tl01kq	274	1	Following	follow	VBG
cord-010027-r0tl01kq	274	2	several	several	JJ
cord-010027-r0tl01kq	274	3	high	high	JJ
cord-010027-r0tl01kq	274	4	profile	profile	NN
cord-010027-r0tl01kq	274	5	misdiagnoses	misdiagnose	NNS
cord-010027-r0tl01kq	274	6	in	in	IN
cord-010027-r0tl01kq	274	7	Ireland	Ireland	NNP
cord-010027-r0tl01kq	274	8	a	a	DT
cord-010027-r0tl01kq	274	9	national	national	JJ
cord-010027-r0tl01kq	274	10	quality	quality	NN
cord-010027-r0tl01kq	274	11	assurance	assurance	NN
cord-010027-r0tl01kq	274	12	(	(	-LRB-
cord-010027-r0tl01kq	274	13	QA	QA	NNP
cord-010027-r0tl01kq	274	14	)	)	-RRB-
cord-010027-r0tl01kq	274	15	programme	programme	NN
cord-010027-r0tl01kq	274	16	for	for	IN
cord-010027-r0tl01kq	274	17	cellular	cellular	JJ
cord-010027-r0tl01kq	274	18	pathology	pathology	NN
cord-010027-r0tl01kq	274	19	in	in	IN
cord-010027-r0tl01kq	274	20	2009	2009	CD
cord-010027-r0tl01kq	274	21	was	be	VBD
cord-010027-r0tl01kq	274	22	initiated	initiate	VBN
cord-010027-r0tl01kq	274	23	with	with	IN
cord-010027-r0tl01kq	274	24	a	a	DT
cord-010027-r0tl01kq	274	25	vision	vision	NN
cord-010027-r0tl01kq	274	26	of	of	IN
cord-010027-r0tl01kq	274	27	establishing	establish	VBG
cord-010027-r0tl01kq	274	28	a	a	DT
cord-010027-r0tl01kq	274	29	patientcentred	patientcentre	VBN
cord-010027-r0tl01kq	274	30	pathologist	pathologist	NN
cord-010027-r0tl01kq	274	31	-	-	HYPH
cord-010027-r0tl01kq	274	32	led	lead	VBN
cord-010027-r0tl01kq	274	33	framework	framework	NN
cord-010027-r0tl01kq	274	34	that	that	WDT
cord-010027-r0tl01kq	274	35	would	would	MD
cord-010027-r0tl01kq	274	36	enhance	enhance	VB
cord-010027-r0tl01kq	274	37	the	the	DT
cord-010027-r0tl01kq	274	38	quality	quality	NN
cord-010027-r0tl01kq	274	39	of	of	IN
cord-010027-r0tl01kq	274	40	patient	patient	JJ
cord-010027-r0tl01kq	274	41	care	care	NN
cord-010027-r0tl01kq	274	42	with	with	IN
cord-010027-r0tl01kq	274	43	timely	timely	JJ
cord-010027-r0tl01kq	274	44	,	,	,
cord-010027-r0tl01kq	274	45	accurate	accurate	JJ
cord-010027-r0tl01kq	274	46	and	and	CC
cord-010027-r0tl01kq	274	47	complete	complete	JJ
cord-010027-r0tl01kq	274	48	pathological	pathological	JJ
cord-010027-r0tl01kq	274	49	diagnoses	diagnosis	NNS
cord-010027-r0tl01kq	274	50	and	and	CC
cord-010027-r0tl01kq	274	51	reporting	reporting	NN
cord-010027-r0tl01kq	274	52	.	.	.
cord-010027-r0tl01kq	275	1	National	National	NNP
cord-010027-r0tl01kq	275	2	QA	QA	NNP
cord-010027-r0tl01kq	275	3	guidelines	guideline	NNS
cord-010027-r0tl01kq	275	4	were	be	VBD
cord-010027-r0tl01kq	275	5	developed	develop	VBN
cord-010027-r0tl01kq	275	6	based	base	VBN
cord-010027-r0tl01kq	275	7	on	on	IN
cord-010027-r0tl01kq	275	8	17	17	CD
cord-010027-r0tl01kq	275	9	key	key	JJ
cord-010027-r0tl01kq	275	10	quality	quality	NN
cord-010027-r0tl01kq	275	11	activities	activity	NNS
cord-010027-r0tl01kq	275	12	generating	generate	VBG
cord-010027-r0tl01kq	275	13	a	a	DT
cord-010027-r0tl01kq	275	14	total	total	NN
cord-010027-r0tl01kq	275	15	of	of	IN
cord-010027-r0tl01kq	275	16	51	51	CD
cord-010027-r0tl01kq	275	17	Key	Key	NNP
cord-010027-r0tl01kq	275	18	Quality	Quality	NNP
cord-010027-r0tl01kq	275	19	Indicators	Indicators	NNP
cord-010027-r0tl01kq	275	20	(	(	-LRB-
cord-010027-r0tl01kq	275	21	KQI	KQI	NNP
cord-010027-r0tl01kq	275	22	)	)	-RRB-
cord-010027-r0tl01kq	275	23	.	.	.
cord-010027-r0tl01kq	276	1	Examples	example	NNS
cord-010027-r0tl01kq	276	2	of	of	IN
cord-010027-r0tl01kq	276	3	the	the	DT
cord-010027-r0tl01kq	276	4	quality	quality	NN
cord-010027-r0tl01kq	276	5	activities	activity	NNS
cord-010027-r0tl01kq	276	6	include	include	VBP
cord-010027-r0tl01kq	276	7	turnaround	turnaround	NN
cord-010027-r0tl01kq	276	8	time	time	NN
cord-010027-r0tl01kq	276	9	,	,	,
cord-010027-r0tl01kq	276	10	monitoring	monitoring	NN
cord-010027-r0tl01kq	276	11	of	of	IN
cord-010027-r0tl01kq	276	12	amended	amend	VBN
cord-010027-r0tl01kq	276	13	reports	report	NNS
cord-010027-r0tl01kq	276	14	,	,	,
cord-010027-r0tl01kq	276	15	frozen	frozen	JJ
cord-010027-r0tl01kq	276	16	section	section	NN
cord-010027-r0tl01kq	276	17	correlation	correlation	NN
cord-010027-r0tl01kq	276	18	and	and	CC
cord-010027-r0tl01kq	276	19	various	various	JJ
cord-010027-r0tl01kq	276	20	elements	element	NNS
cord-010027-r0tl01kq	276	21	of	of	IN
cord-010027-r0tl01kq	276	22	peer	peer	NN
cord-010027-r0tl01kq	276	23	review	review	NN
cord-010027-r0tl01kq	276	24	.	.	.
cord-010027-r0tl01kq	277	1	All	all	DT
cord-010027-r0tl01kq	277	2	25	25	CD
cord-010027-r0tl01kq	277	3	cellular	cellular	JJ
cord-010027-r0tl01kq	277	4	pathology	pathology	NN
cord-010027-r0tl01kq	277	5	departments	department	NNS
cord-010027-r0tl01kq	277	6	in	in	IN
cord-010027-r0tl01kq	277	7	the	the	DT
cord-010027-r0tl01kq	277	8	public	public	JJ
cord-010027-r0tl01kq	277	9	state	state	NN
cord-010027-r0tl01kq	277	10	-	-	HYPH
cord-010027-r0tl01kq	277	11	funded	fund	VBN
cord-010027-r0tl01kq	277	12	hospitals	hospital	NNS
cord-010027-r0tl01kq	277	13	participate	participate	VBP
cord-010027-r0tl01kq	277	14	in	in	IN
cord-010027-r0tl01kq	277	15	the	the	DT
cord-010027-r0tl01kq	277	16	programme	programme	NN
cord-010027-r0tl01kq	277	17	in	in	IN
cord-010027-r0tl01kq	277	18	addition	addition	NN
cord-010027-r0tl01kq	277	19	to	to	IN
cord-010027-r0tl01kq	277	20	7	7	CD
cord-010027-r0tl01kq	277	21	laboratories	laboratory	NNS
cord-010027-r0tl01kq	277	22	within	within	IN
cord-010027-r0tl01kq	277	23	privately	privately	RB
cord-010027-r0tl01kq	277	24	-	-	HYPH
cord-010027-r0tl01kq	277	25	run	run	VBN
cord-010027-r0tl01kq	277	26	hospitals	hospital	NNS
cord-010027-r0tl01kq	277	27	.	.	.
cord-010027-r0tl01kq	278	1	Each	each	DT
cord-010027-r0tl01kq	278	2	laboratory	laboratory	NN
cord-010027-r0tl01kq	278	3	enters	enter	VBZ
cord-010027-r0tl01kq	278	4	codes	code	NNS
cord-010027-r0tl01kq	278	5	on	on	IN
cord-010027-r0tl01kq	278	6	individual	individual	JJ
cord-010027-r0tl01kq	278	7	cases	case	NNS
cord-010027-r0tl01kq	278	8	designed	design	VBN
cord-010027-r0tl01kq	278	9	to	to	TO
cord-010027-r0tl01kq	278	10	capture	capture	VB
cord-010027-r0tl01kq	278	11	the	the	DT
cord-010027-r0tl01kq	278	12	relevant	relevant	JJ
cord-010027-r0tl01kq	278	13	KQI	KQI	NNP
cord-010027-r0tl01kq	278	14	and	and	CC
cord-010027-r0tl01kq	278	15	the	the	DT
cord-010027-r0tl01kq	278	16	anonymised	anonymised	JJ
cord-010027-r0tl01kq	278	17	encrypted	encrypt	VBN
cord-010027-r0tl01kq	278	18	QA	QA	NNP
cord-010027-r0tl01kq	278	19	data	data	NN
cord-010027-r0tl01kq	278	20	is	be	VBZ
cord-010027-r0tl01kq	278	21	then	then	RB
cord-010027-r0tl01kq	278	22	electronically	electronically	RB
cord-010027-r0tl01kq	278	23	extracted	extract	VBN
cord-010027-r0tl01kq	278	24	from	from	IN
cord-010027-r0tl01kq	278	25	the	the	DT
cord-010027-r0tl01kq	278	26	laboratory	laboratory	NN
cord-010027-r0tl01kq	278	27	information	information	NN
cord-010027-r0tl01kq	278	28	system	system	NN
cord-010027-r0tl01kq	278	29	to	to	IN
cord-010027-r0tl01kq	278	30	a	a	DT
cord-010027-r0tl01kq	278	31	national	national	JJ
cord-010027-r0tl01kq	278	32	database	database	NN
cord-010027-r0tl01kq	278	33	.	.	.
cord-010027-r0tl01kq	279	1	This	this	DT
cord-010027-r0tl01kq	279	2	national	national	JJ
cord-010027-r0tl01kq	279	3	central	central	JJ
cord-010027-r0tl01kq	279	4	database	database	NN
cord-010027-r0tl01kq	279	5	is	be	VBZ
cord-010027-r0tl01kq	279	6	managed	manage	VBN
cord-010027-r0tl01kq	279	7	by	by	IN
cord-010027-r0tl01kq	279	8	a	a	DT
cord-010027-r0tl01kq	279	9	novel	novel	JJ
cord-010027-r0tl01kq	279	10	information	information	NN
cord-010027-r0tl01kq	279	11	technology	technology	NN
cord-010027-r0tl01kq	279	12	system	system	NN
cord-010027-r0tl01kq	279	13	,	,	,
cord-010027-r0tl01kq	279	14	the	the	DT
cord-010027-r0tl01kq	279	15	National	National	NNP
cord-010027-r0tl01kq	279	16	Quality	Quality	NNP
cord-010027-r0tl01kq	279	17	Assurance	Assurance	NNP
cord-010027-r0tl01kq	279	18	Intelligence	Intelligence	NNP
cord-010027-r0tl01kq	279	19	System	System	NNP
cord-010027-r0tl01kq	279	20	(	(	-LRB-
cord-010027-r0tl01kq	279	21	NQAIS)-Histopathology	NQAIS)-Histopathology	NNP
cord-010027-r0tl01kq	279	22	,	,	,
cord-010027-r0tl01kq	279	23	that	that	WDT
cord-010027-r0tl01kq	279	24	was	be	VBD
cord-010027-r0tl01kq	279	25	designed	design	VBN
cord-010027-r0tl01kq	279	26	to	to	TO
cord-010027-r0tl01kq	279	27	process	process	VB
cord-010027-r0tl01kq	279	28	and	and	CC
cord-010027-r0tl01kq	279	29	display	display	VB
cord-010027-r0tl01kq	279	30	the	the	DT
cord-010027-r0tl01kq	279	31	QA	QA	NNP
cord-010027-r0tl01kq	279	32	data	datum	NNS
cord-010027-r0tl01kq	279	33	so	so	IN
cord-010027-r0tl01kq	279	34	that	that	IN
cord-010027-r0tl01kq	279	35	each	each	DT
cord-010027-r0tl01kq	279	36	individual	individual	JJ
cord-010027-r0tl01kq	279	37	laboratory	laboratory	NN
cord-010027-r0tl01kq	279	38	can	can	MD
cord-010027-r0tl01kq	279	39	analyse	analyse	VB
cord-010027-r0tl01kq	279	40	their	-PRON-	PRP$
cord-010027-r0tl01kq	279	41	own	own	JJ
cord-010027-r0tl01kq	279	42	data	datum	NNS
cord-010027-r0tl01kq	279	43	and	and	CC
cord-010027-r0tl01kq	279	44	also	also	RB
cord-010027-r0tl01kq	279	45	compare	compare	VBP
cord-010027-r0tl01kq	279	46	their	-PRON-	PRP$
cord-010027-r0tl01kq	279	47	performance	performance	NN
cord-010027-r0tl01kq	279	48	to	to	IN
cord-010027-r0tl01kq	279	49	the	the	DT
cord-010027-r0tl01kq	279	50	national	national	JJ
cord-010027-r0tl01kq	279	51	average	average	NN
cord-010027-r0tl01kq	279	52	for	for	IN
cord-010027-r0tl01kq	279	53	each	each	DT
cord-010027-r0tl01kq	279	54	KQI	KQI	NNP
cord-010027-r0tl01kq	279	55	.	.	.
cord-010027-r0tl01kq	280	1	Since	since	IN
cord-010027-r0tl01kq	280	2	2013	2013	CD
cord-010027-r0tl01kq	280	3	complete	complete	JJ
cord-010027-r0tl01kq	280	4	national	national	JJ
cord-010027-r0tl01kq	280	5	data	datum	NNS
cord-010027-r0tl01kq	280	6	has	have	VBZ
cord-010027-r0tl01kq	280	7	been	be	VBN
cord-010027-r0tl01kq	280	8	inputted	inputte	VBN
cord-010027-r0tl01kq	280	9	into	into	IN
cord-010027-r0tl01kq	280	10	the	the	DT
cord-010027-r0tl01kq	280	11	NQAIS	NQAIS	NNP
cord-010027-r0tl01kq	280	12	system	system	NN
cord-010027-r0tl01kq	280	13	and	and	CC
cord-010027-r0tl01kq	280	14	in	in	IN
cord-010027-r0tl01kq	280	15	2014	2014	CD
cord-010027-r0tl01kq	280	16	initial	initial	JJ
cord-010027-r0tl01kq	280	17	QA	QA	NNP
cord-010027-r0tl01kq	280	18	targets	target	NNS
cord-010027-r0tl01kq	280	19	were	be	VBD
cord-010027-r0tl01kq	280	20	agreed	agree	VBN
cord-010027-r0tl01kq	280	21	for	for	IN
cord-010027-r0tl01kq	280	22	turnaround	turnaround	NN
cord-010027-r0tl01kq	280	23	time	time	NN
cord-010027-r0tl01kq	280	24	,	,	,
cord-010027-r0tl01kq	280	25	frozen	frozen	JJ
cord-010027-r0tl01kq	280	26	section	section	NN
cord-010027-r0tl01kq	280	27	correlation	correlation	NN
cord-010027-r0tl01kq	280	28	and	and	CC
cord-010027-r0tl01kq	280	29	rate	rate	NN
cord-010027-r0tl01kq	280	30	of	of	IN
cord-010027-r0tl01kq	280	31	intra	intra	JJ
cord-010027-r0tl01kq	280	32	-	-	JJ
cord-010027-r0tl01kq	280	33	departmental	departmental	JJ
cord-010027-r0tl01kq	280	34	consultation	consultation	NN
cord-010027-r0tl01kq	280	35	(	(	-LRB-
cord-010027-r0tl01kq	280	36	IDC	IDC	NNP
cord-010027-r0tl01kq	280	37	)	)	-RRB-
cord-010027-r0tl01kq	280	38	.	.	.
cord-010027-r0tl01kq	281	1	In	in	IN
cord-010027-r0tl01kq	281	2	2015	2015	CD
cord-010027-r0tl01kq	281	3	additional	additional	JJ
cord-010027-r0tl01kq	281	4	targets	target	NNS
cord-010027-r0tl01kq	281	5	for	for	IN
cord-010027-r0tl01kq	281	6	autopsy	autopsy	JJ
cord-010027-r0tl01kq	281	7	ICD	ICD	NNP
cord-010027-r0tl01kq	281	8	,	,	,
cord-010027-r0tl01kq	281	9	frozen	frozen	JJ
cord-010027-r0tl01kq	281	10	section	section	NN
cord-010027-r0tl01kq	281	11	deferral	deferral	NN
cord-010027-r0tl01kq	281	12	rate	rate	NN
cord-010027-r0tl01kq	281	13	and	and	CC
cord-010027-r0tl01kq	281	14	turnaround	turnaround	NN
cord-010027-r0tl01kq	281	15	time	time	NN
cord-010027-r0tl01kq	281	16	have	have	VBP
cord-010027-r0tl01kq	281	17	been	be	VBN
cord-010027-r0tl01kq	281	18	added	add	VBN
cord-010027-r0tl01kq	281	19	.	.	.
cord-010027-r0tl01kq	282	1	To	to	IN
cord-010027-r0tl01kq	282	2	our	-PRON-	PRP$
cord-010027-r0tl01kq	282	3	knowledge	knowledge	NN
cord-010027-r0tl01kq	282	4	this	this	DT
cord-010027-r0tl01kq	282	5	programme	programme	NN
cord-010027-r0tl01kq	282	6	has	have	VBZ
cord-010027-r0tl01kq	282	7	enabled	enable	VBN
cord-010027-r0tl01kq	282	8	Ireland	Ireland	NNP
cord-010027-r0tl01kq	282	9	to	to	TO
cord-010027-r0tl01kq	282	10	be	be	VB
cord-010027-r0tl01kq	282	11	the	the	DT
cord-010027-r0tl01kq	282	12	first	first	JJ
cord-010027-r0tl01kq	282	13	country	country	NN
cord-010027-r0tl01kq	282	14	to	to	TO
cord-010027-r0tl01kq	282	15	publically	publically	RB
cord-010027-r0tl01kq	282	16	report	report	VB
cord-010027-r0tl01kq	282	17	national	national	JJ
cord-010027-r0tl01kq	282	18	metrics	metric	NNS
cord-010027-r0tl01kq	282	19	on	on	IN
cord-010027-r0tl01kq	282	20	the	the	DT
cord-010027-r0tl01kq	282	21	quality	quality	NN
cord-010027-r0tl01kq	282	22	of	of	IN
cord-010027-r0tl01kq	282	23	their	-PRON-	PRP$
cord-010027-r0tl01kq	282	24	pathology	pathology	NN
cord-010027-r0tl01kq	282	25	services	service	NNS
cord-010027-r0tl01kq	282	26	.	.	.
cord-010027-r0tl01kq	283	1			.
cord-010027-r0tl01kq	284	1	The	the	DT
cord-010027-r0tl01kq	284	2	Politics	Politics	NNPS
cord-010027-r0tl01kq	284	3	of	of	IN
cord-010027-r0tl01kq	284	4	EQA	EQA	NNP
cord-010027-r0tl01kq	284	5	:	:	:
cord-010027-r0tl01kq	285	1	The	the	DT
cord-010027-r0tl01kq	285	2	NHS	NHS	NNP
cord-010027-r0tl01kq	285	3	England	England	NNP
cord-010027-r0tl01kq	285	4	QA	QA	NNP
cord-010027-r0tl01kq	285	5	Review	Review	NNP
cord-010027-r0tl01kq	285	6	and	and	CC
cord-010027-r0tl01kq	285	7	its	-PRON-	PRP$
cord-010027-r0tl01kq	285	8	Consequences	consequence	NNS
cord-010027-r0tl01kq	285	9	P	P	NNP
cord-010027-r0tl01kq	285	10	DE	DE	NNP
cord-010027-r0tl01kq	285	11	Hughes	Hughes	NNP
cord-010027-r0tl01kq	286	1	In	in	IN
cord-010027-r0tl01kq	286	2	2013	2013	CD
cord-010027-r0tl01kq	286	3	,	,	,
cord-010027-r0tl01kq	286	4	a	a	DT
cord-010027-r0tl01kq	286	5	review	review	NN
cord-010027-r0tl01kq	286	6	of	of	IN
cord-010027-r0tl01kq	286	7	External	External	NNP
cord-010027-r0tl01kq	286	8	Quality	Quality	NNP
cord-010027-r0tl01kq	286	9	Assessment	Assessment	NNP
cord-010027-r0tl01kq	286	10	processes	process	NNS
cord-010027-r0tl01kq	286	11	was	be	VBD
cord-010027-r0tl01kq	286	12	carried	carry	VBN
cord-010027-r0tl01kq	286	13	out	out	RP
cord-010027-r0tl01kq	286	14	on	on	IN
cord-010027-r0tl01kq	286	15	behalf	behalf	NN
cord-010027-r0tl01kq	286	16	of	of	IN
cord-010027-r0tl01kq	286	17	NHS	NHS	NNP
cord-010027-r0tl01kq	286	18	England	England	NNP
cord-010027-r0tl01kq	286	19	.	.	.
cord-010027-r0tl01kq	287	1	The	the	DT
cord-010027-r0tl01kq	287	2	main	main	JJ
cord-010027-r0tl01kq	287	3	recommendations	recommendation	NNS
cord-010027-r0tl01kq	287	4	of	of	IN
cord-010027-r0tl01kq	287	5	this	this	DT
cord-010027-r0tl01kq	287	6	review	review	NN
cord-010027-r0tl01kq	287	7	related	relate	VBN
cord-010027-r0tl01kq	287	8	to	to	IN
cord-010027-r0tl01kq	287	9	the	the	DT
cord-010027-r0tl01kq	287	10	strengthening	strengthening	NN
cord-010027-r0tl01kq	287	11	of	of	IN
cord-010027-r0tl01kq	287	12	governance	governance	NN
cord-010027-r0tl01kq	287	13	of	of	IN
cord-010027-r0tl01kq	287	14	EQA	EQA	NNP
cord-010027-r0tl01kq	287	15	,	,	,
cord-010027-r0tl01kq	287	16	both	both	CC
cord-010027-r0tl01kq	287	17	nationally	nationally	RB
cord-010027-r0tl01kq	287	18	and	and	CC
cord-010027-r0tl01kq	287	19	within	within	IN
cord-010027-r0tl01kq	287	20	pathology	pathology	NN
cord-010027-r0tl01kq	287	21	provider	provider	NN
cord-010027-r0tl01kq	287	22	organisations	organisation	NNS
cord-010027-r0tl01kq	287	23	.	.	.
cord-010027-r0tl01kq	288	1	Recommendations	recommendation	NNS
cord-010027-r0tl01kq	288	2	specifically	specifically	RB
cord-010027-r0tl01kq	288	3	affecting	affect	VBG
cord-010027-r0tl01kq	288	4	Cellular	Cellular	NNP
cord-010027-r0tl01kq	288	5	Pathology	Pathology	NNP
cord-010027-r0tl01kq	288	6	were	be	VBD
cord-010027-r0tl01kq	288	7	:	:	:
cord-010027-r0tl01kq	288	8	(	(	-LRB-
cord-010027-r0tl01kq	288	9	i	i	NN
cord-010027-r0tl01kq	288	10	)	)	-RRB-
cord-010027-r0tl01kq	288	11	Professional	professional	JJ
cord-010027-r0tl01kq	288	12	bodies	body	NNS
cord-010027-r0tl01kq	288	13	,	,	,
cord-010027-r0tl01kq	288	14	led	lead	VBN
cord-010027-r0tl01kq	288	15	by	by	IN
cord-010027-r0tl01kq	288	16	RCPath	RCPath	NNP
cord-010027-r0tl01kq	288	17	,	,	,
cord-010027-r0tl01kq	288	18	should	should	MD
cord-010027-r0tl01kq	288	19	develop	develop	VB
cord-010027-r0tl01kq	288	20	methodologies	methodology	NNS
cord-010027-r0tl01kq	288	21	for	for	IN
cord-010027-r0tl01kq	288	22	assessing	assess	VBG
cord-010027-r0tl01kq	288	23	the	the	DT
cord-010027-r0tl01kq	288	24	performance	performance	NN
cord-010027-r0tl01kq	288	25	of	of	IN
cord-010027-r0tl01kq	288	26	individuals	individual	NNS
cord-010027-r0tl01kq	288	27	in	in	IN
cord-010027-r0tl01kq	288	28	EQA	EQA	NNP
cord-010027-r0tl01kq	288	29	schemes	scheme	NNS
cord-010027-r0tl01kq	288	30	.	.	.
cord-010027-r0tl01kq	289	1	(	(	-LRB-
cord-010027-r0tl01kq	289	2	ii	ii	NN
cord-010027-r0tl01kq	289	3	)	)	-RRB-
cord-010027-r0tl01kq	290	1	All	all	DT
cord-010027-r0tl01kq	290	2	pathologists	pathologist	NNS
cord-010027-r0tl01kq	290	3	reporting	report	VBG
cord-010027-r0tl01kq	290	4	pathology	pathology	NN
cord-010027-r0tl01kq	290	5	results	result	NNS
cord-010027-r0tl01kq	290	6	and	and	CC
cord-010027-r0tl01kq	290	7	providing	provide	VBG
cord-010027-r0tl01kq	290	8	clinical	clinical	JJ
cord-010027-r0tl01kq	290	9	advice	advice	NN
cord-010027-r0tl01kq	290	10	should	should	MD
cord-010027-r0tl01kq	290	11	be	be	VB
cord-010027-r0tl01kq	290	12	participate	participate	VB
cord-010027-r0tl01kq	290	13	in	in	IN
cord-010027-r0tl01kq	290	14	EQA	EQA	NNP
cord-010027-r0tl01kq	290	15	schemes	scheme	NNS
cord-010027-r0tl01kq	290	16	relevant	relevant	JJ
cord-010027-r0tl01kq	290	17	to	to	IN
cord-010027-r0tl01kq	290	18	their	-PRON-	PRP$
cord-010027-r0tl01kq	290	19	practice	practice	NN
cord-010027-r0tl01kq	290	20	,	,	,
cord-010027-r0tl01kq	290	21	should	should	MD
cord-010027-r0tl01kq	290	22	achieve	achieve	VB
cord-010027-r0tl01kq	290	23	levels	level	NNS
cord-010027-r0tl01kq	290	24	of	of	IN
cord-010027-r0tl01kq	290	25	performance	performance	NN
cord-010027-r0tl01kq	290	26	determined	determine	VBN
cord-010027-r0tl01kq	290	27	by	by	IN
cord-010027-r0tl01kq	290	28	the	the	DT
cord-010027-r0tl01kq	290	29	professional	professional	JJ
cord-010027-r0tl01kq	290	30	bodies	body	NNS
cord-010027-r0tl01kq	290	31	and	and	CC
cord-010027-r0tl01kq	290	32	this	this	DT
cord-010027-r0tl01kq	290	33	performance	performance	NN
cord-010027-r0tl01kq	290	34	should	should	MD
cord-010027-r0tl01kq	290	35	be	be	VB
cord-010027-r0tl01kq	290	36	noted	note	VBN
cord-010027-r0tl01kq	290	37	at	at	IN
cord-010027-r0tl01kq	290	38	annual	annual	JJ
cord-010027-r0tl01kq	290	39	appraisal	appraisal	NN
cord-010027-r0tl01kq	290	40	.	.	.
cord-010027-r0tl01kq	291	1	(	(	-LRB-
cord-010027-r0tl01kq	291	2	iii	iii	NN
cord-010027-r0tl01kq	291	3	)	)	-RRB-
cord-010027-r0tl01kq	292	1	Where	where	WRB
cord-010027-r0tl01kq	292	2	a	a	DT
cord-010027-r0tl01kq	292	3	need	need	NN
cord-010027-r0tl01kq	292	4	to	to	TO
cord-010027-r0tl01kq	292	5	improve	improve	VB
cord-010027-r0tl01kq	292	6	performance	performance	NN
cord-010027-r0tl01kq	292	7	is	be	VBZ
cord-010027-r0tl01kq	292	8	identified	identify	VBN
cord-010027-r0tl01kq	292	9	,	,	,
cord-010027-r0tl01kq	292	10	additional	additional	JJ
cord-010027-r0tl01kq	292	11	remedial	remedial	JJ
cord-010027-r0tl01kq	292	12	training	training	NN
cord-010027-r0tl01kq	292	13	should	should	MD
cord-010027-r0tl01kq	292	14	be	be	VB
cord-010027-r0tl01kq	292	15	carried	carry	VBN
cord-010027-r0tl01kq	292	16	out	out	RP
cord-010027-r0tl01kq	292	17	,	,	,
cord-010027-r0tl01kq	292	18	or	or	CC
cord-010027-r0tl01kq	292	19	practice	practice	VB
cord-010027-r0tl01kq	292	20	in	in	IN
cord-010027-r0tl01kq	292	21	the	the	DT
cord-010027-r0tl01kq	292	22	area	area	NN
cord-010027-r0tl01kq	292	23	of	of	IN
cord-010027-r0tl01kq	292	24	concern	concern	NN
cord-010027-r0tl01kq	292	25	should	should	MD
cord-010027-r0tl01kq	292	26	be	be	VB
cord-010027-r0tl01kq	292	27	stopped	stop	VBN
cord-010027-r0tl01kq	292	28	until	until	IN
cord-010027-r0tl01kq	292	29	appropriate	appropriate	JJ
cord-010027-r0tl01kq	292	30	retraining	retraining	NN
cord-010027-r0tl01kq	292	31	has	have	VBZ
cord-010027-r0tl01kq	292	32	been	be	VBN
cord-010027-r0tl01kq	292	33	undertaken	undertake	VBN
cord-010027-r0tl01kq	292	34	and	and	CC
cord-010027-r0tl01kq	292	35	revalidation	revalidation	NN
cord-010027-r0tl01kq	292	36	achieved	achieve	VBN
cord-010027-r0tl01kq	292	37	.	.	.
cord-010027-r0tl01kq	293	1	This	this	DT
cord-010027-r0tl01kq	293	2	process	process	NN
cord-010027-r0tl01kq	293	3	should	should	MD
cord-010027-r0tl01kq	293	4	supported	support	VBN
cord-010027-r0tl01kq	293	5	and	and	CC
cord-010027-r0tl01kq	293	6	resourced	resource	VBN
cord-010027-r0tl01kq	293	7	by	by	IN
cord-010027-r0tl01kq	293	8	the	the	DT
cord-010027-r0tl01kq	293	9	employing	employ	VBG
cord-010027-r0tl01kq	293	10	organisation	organisation	NN
cord-010027-r0tl01kq	293	11	,	,	,
cord-010027-r0tl01kq	293	12	as	as	IN
cord-010027-r0tl01kq	293	13	should	should	MD
cord-010027-r0tl01kq	293	14	EQA	eqa	VB
cord-010027-r0tl01kq	293	15	scheme	scheme	NN
cord-010027-r0tl01kq	293	16	participation	participation	NN
cord-010027-r0tl01kq	293	17	.	.	.
cord-010027-r0tl01kq	294	1	(	(	-LRB-
cord-010027-r0tl01kq	294	2	iv	iv	LS
cord-010027-r0tl01kq	294	3	)	)	-RRB-
cord-010027-r0tl01kq	294	4	Interpretative	interpretative	JJ
cord-010027-r0tl01kq	294	5	EQA	EQA	NNP
cord-010027-r0tl01kq	294	6	schemes	scheme	NNS
cord-010027-r0tl01kq	294	7	are	be	VBP
cord-010027-r0tl01kq	294	8	designed	design	VBN
cord-010027-r0tl01kq	294	9	to	to	TO
cord-010027-r0tl01kq	294	10	assess	assess	VB
cord-010027-r0tl01kq	294	11	and	and	CC
cord-010027-r0tl01kq	294	12	improve	improve	VB
cord-010027-r0tl01kq	294	13	individual	individual	JJ
cord-010027-r0tl01kq	294	14	performance	performance	NN
cord-010027-r0tl01kq	294	15	,	,	,
cord-010027-r0tl01kq	294	16	and	and	CC
cord-010027-r0tl01kq	294	17	attempts	attempt	VBZ
cord-010027-r0tl01kq	294	18	at	at	IN
cord-010027-r0tl01kq	294	19	collusion	collusion	NN
cord-010027-r0tl01kq	294	20	are	be	VBP
cord-010027-r0tl01kq	294	21	considered	consider	VBN
cord-010027-r0tl01kq	294	22	matters	matter	NNS
cord-010027-r0tl01kq	294	23	of	of	IN
cord-010027-r0tl01kq	294	24	professional	professional	JJ
cord-010027-r0tl01kq	294	25	probity	probity	NN
cord-010027-r0tl01kq	294	26	.	.	.
cord-010027-r0tl01kq	295	1	The	the	DT
cord-010027-r0tl01kq	295	2	professional	professional	JJ
cord-010027-r0tl01kq	295	3	response	response	NN
cord-010027-r0tl01kq	295	4	to	to	IN
cord-010027-r0tl01kq	295	5	these	these	DT
cord-010027-r0tl01kq	295	6	recommendations	recommendation	NNS
cord-010027-r0tl01kq	295	7	is	be	VBZ
cord-010027-r0tl01kq	295	8	expected	expect	VBN
cord-010027-r0tl01kq	295	9	to	to	TO
cord-010027-r0tl01kq	295	10	be	be	VB
cord-010027-r0tl01kq	295	11	led	lead	VBN
cord-010027-r0tl01kq	295	12	by	by	IN
cord-010027-r0tl01kq	295	13	the	the	DT
cord-010027-r0tl01kq	295	14	RCPath	RCPath	NNP
cord-010027-r0tl01kq	295	15	under	under	IN
cord-010027-r0tl01kq	295	16	the	the	DT
cord-010027-r0tl01kq	295	17	guidance	guidance	NN
cord-010027-r0tl01kq	295	18	of	of	IN
cord-010027-r0tl01kq	295	19	a	a	DT
cord-010027-r0tl01kq	295	20	newly	newly	RB
cord-010027-r0tl01kq	295	21	-	-	HYPH
cord-010027-r0tl01kq	295	22	established	establish	VBN
cord-010027-r0tl01kq	295	23	national	national	JJ
cord-010027-r0tl01kq	295	24	oversight	oversight	NN
cord-010027-r0tl01kq	295	25	group	group	NN
cord-010027-r0tl01kq	295	26	working	work	VBG
cord-010027-r0tl01kq	295	27	on	on	IN
cord-010027-r0tl01kq	295	28	behalf	behalf	NN
cord-010027-r0tl01kq	295	29	of	of	IN
cord-010027-r0tl01kq	295	30	NHS	NHS	NNP
cord-010027-r0tl01kq	295	31	England	England	NNP
cord-010027-r0tl01kq	295	32	and	and	CC
cord-010027-r0tl01kq	295	33	should	should	MD
cord-010027-r0tl01kq	295	34	be	be	VB
cord-010027-r0tl01kq	295	35	more	more	RBR
cord-010027-r0tl01kq	295	36	clear	clear	JJ
cord-010027-r0tl01kq	295	37	at	at	IN
cord-010027-r0tl01kq	295	38	the	the	DT
cord-010027-r0tl01kq	295	39	time	time	NN
cord-010027-r0tl01kq	295	40	of	of	IN
cord-010027-r0tl01kq	295	41	the	the	DT
cord-010027-r0tl01kq	295	42	Pathsoc	Pathsoc	NNP
cord-010027-r0tl01kq	295	43	conference	conference	NN
cord-010027-r0tl01kq	295	44	.	.	.
cord-010027-r0tl01kq	296	1	A	a	DT
cord-010027-r0tl01kq	296	2	key	key	JJ
cord-010027-r0tl01kq	296	3	part	part	NN
cord-010027-r0tl01kq	296	4	of	of	IN
cord-010027-r0tl01kq	296	5	this	this	DT
cord-010027-r0tl01kq	296	6	response	response	NN
cord-010027-r0tl01kq	296	7	will	will	MD
cord-010027-r0tl01kq	296	8	be	be	VB
cord-010027-r0tl01kq	296	9	to	to	TO
cord-010027-r0tl01kq	296	10	separately	separately	RB
cord-010027-r0tl01kq	296	11	consider	consider	VB
cord-010027-r0tl01kq	296	12	the	the	DT
cord-010027-r0tl01kq	296	13	implications	implication	NNS
cord-010027-r0tl01kq	296	14	of	of	IN
cord-010027-r0tl01kq	296	15	this	this	DT
cord-010027-r0tl01kq	296	16	review	review	NN
cord-010027-r0tl01kq	296	17	for	for	IN
cord-010027-r0tl01kq	296	18	technical	technical	JJ
cord-010027-r0tl01kq	296	19	schemes	scheme	NNS
cord-010027-r0tl01kq	296	20	,	,	,
cord-010027-r0tl01kq	296	21	affecting	affect	VBG
cord-010027-r0tl01kq	296	22	laboratories	laboratory	NNS
cord-010027-r0tl01kq	296	23	,	,	,
cord-010027-r0tl01kq	296	24	and	and	CC
cord-010027-r0tl01kq	296	25	interpretative	interpretative	JJ
cord-010027-r0tl01kq	296	26	schemes	scheme	NNS
cord-010027-r0tl01kq	296	27	,	,	,
cord-010027-r0tl01kq	296	28	affecting	affect	VBG
cord-010027-r0tl01kq	296	29	individual	individual	JJ
cord-010027-r0tl01kq	296	30	practitioners	practitioner	NNS
cord-010027-r0tl01kq	296	31	.	.	.
cord-010027-r0tl01kq	297	1	Roche	Roche	NNP
cord-010027-r0tl01kq	297	2	Tissue	Tissue	NNP
cord-010027-r0tl01kq	297	3	Diagnostics	Diagnostics	NNP
cord-010027-r0tl01kq	297	4	,	,	,
cord-010027-r0tl01kq	297	5	Tucson	Tucson	NNP
cord-010027-r0tl01kq	297	6	,	,	,
cord-010027-r0tl01kq	297	7	Arizona	Arizona	NNP
cord-010027-r0tl01kq	297	8	,	,	,
cord-010027-r0tl01kq	297	9	USA	USA	NNP
cord-010027-r0tl01kq	297	10	Tumour	tumour	NN
cord-010027-r0tl01kq	297	11	samples	sample	NNS
cord-010027-r0tl01kq	297	12	to	to	TO
cord-010027-r0tl01kq	297	13	guide	guide	VB
cord-010027-r0tl01kq	297	14	treatment	treatment	NN
cord-010027-r0tl01kq	297	15	decisions	decision	NNS
cord-010027-r0tl01kq	297	16	have	have	VBP
cord-010027-r0tl01kq	297	17	become	become	VBN
cord-010027-r0tl01kq	297	18	of	of	IN
cord-010027-r0tl01kq	297	19	increasing	increase	VBG
cord-010027-r0tl01kq	297	20	significance	significance	NN
cord-010027-r0tl01kq	297	21	.	.	.
cord-010027-r0tl01kq	298	1	Most	most	RBS
cord-010027-r0tl01kq	298	2	importantly	importantly	RB
cord-010027-r0tl01kq	298	3	the	the	DT
cord-010027-r0tl01kq	298	4	results	result	NNS
cord-010027-r0tl01kq	298	5	of	of	IN
cord-010027-r0tl01kq	298	6	companion	companion	NN
cord-010027-r0tl01kq	298	7	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	298	8	testing	testing	NN
cord-010027-r0tl01kq	298	9	directly	directly	RB
cord-010027-r0tl01kq	298	10	influences	influence	VBZ
cord-010027-r0tl01kq	298	11	the	the	DT
cord-010027-r0tl01kq	298	12	management	management	NN
cord-010027-r0tl01kq	298	13	of	of	IN
cord-010027-r0tl01kq	298	14	individual	individual	JJ
cord-010027-r0tl01kq	298	15	patients	patient	NNS
cord-010027-r0tl01kq	298	16	as	as	IN
cord-010027-r0tl01kq	298	17	more	more	JJR
cord-010027-r0tl01kq	298	18	drugs	drug	NNS
cord-010027-r0tl01kq	298	19	are	be	VBP
cord-010027-r0tl01kq	298	20	approved	approve	VBN
cord-010027-r0tl01kq	298	21	for	for	IN
cord-010027-r0tl01kq	298	22	treatment	treatment	NN
cord-010027-r0tl01kq	298	23	of	of	IN
cord-010027-r0tl01kq	298	24	specific	specific	JJ
cord-010027-r0tl01kq	298	25	molecular	molecular	JJ
cord-010027-r0tl01kq	298	26	distinct	distinct	JJ
cord-010027-r0tl01kq	298	27	subgroups	subgroup	NNS
cord-010027-r0tl01kq	298	28	.	.	.
cord-010027-r0tl01kq	299	1	Reporting	report	VBG
cord-010027-r0tl01kq	299	2	suboptimal	suboptimal	JJ
cord-010027-r0tl01kq	299	3	quality	quality	NN
cord-010027-r0tl01kq	299	4	test	test	NN
cord-010027-r0tl01kq	299	5	results	result	NNS
cord-010027-r0tl01kq	299	6	may	may	MD
cord-010027-r0tl01kq	299	7	be	be	VB
cord-010027-r0tl01kq	299	8	harmful	harmful	JJ
cord-010027-r0tl01kq	299	9	to	to	IN
cord-010027-r0tl01kq	299	10	the	the	DT
cord-010027-r0tl01kq	299	11	patient	patient	NN
cord-010027-r0tl01kq	299	12	and	and	CC
cord-010027-r0tl01kq	299	13	cause	cause	VB
cord-010027-r0tl01kq	299	14	the	the	DT
cord-010027-r0tl01kq	299	15	mismanagement	mismanagement	NN
cord-010027-r0tl01kq	299	16	of	of	IN
cord-010027-r0tl01kq	299	17	a	a	DT
cord-010027-r0tl01kq	299	18	prescribed	prescribed	JJ
cord-010027-r0tl01kq	299	19	companion	companion	NN
cord-010027-r0tl01kq	299	20	drug	drug	NN
cord-010027-r0tl01kq	299	21	.	.	.
cord-010027-r0tl01kq	300	1	The	the	DT
cord-010027-r0tl01kq	300	2	consequences	consequence	NNS
cord-010027-r0tl01kq	300	3	of	of	IN
cord-010027-r0tl01kq	300	4	unsatisfactory	unsatisfactory	JJ
cord-010027-r0tl01kq	300	5	performance	performance	NN
cord-010027-r0tl01kq	300	6	and	and	CC
cord-010027-r0tl01kq	300	7	measures	measure	NNS
cord-010027-r0tl01kq	300	8	for	for	IN
cord-010027-r0tl01kq	300	9	improvement	improvement	NN
cord-010027-r0tl01kq	300	10	are	be	VBP
cord-010027-r0tl01kq	300	11	the	the	DT
cord-010027-r0tl01kq	300	12	responsibility	responsibility	NN
cord-010027-r0tl01kq	300	13	of	of	IN
cord-010027-r0tl01kq	300	14	the	the	DT
cord-010027-r0tl01kq	300	15	laboratory	laboratory	NN
cord-010027-r0tl01kq	300	16	.	.	.
cord-010027-r0tl01kq	301	1	Presently	presently	RB
cord-010027-r0tl01kq	301	2	,	,	,
cord-010027-r0tl01kq	301	3	there	there	EX
cord-010027-r0tl01kq	301	4	are	be	VBP
cord-010027-r0tl01kq	301	5	number	number	NN
cord-010027-r0tl01kq	301	6	of	of	IN
cord-010027-r0tl01kq	301	7	EQA	EQA	NNP
cord-010027-r0tl01kq	301	8	schemes	scheme	NNS
cord-010027-r0tl01kq	301	9	for	for	IN
cord-010027-r0tl01kq	301	10	molecular	molecular	JJ
cord-010027-r0tl01kq	301	11	testing	testing	NN
cord-010027-r0tl01kq	301	12	available	available	JJ
cord-010027-r0tl01kq	301	13	in	in	IN
cord-010027-r0tl01kq	301	14	Europe	Europe	NNP
cord-010027-r0tl01kq	301	15	however	however	RB
cord-010027-r0tl01kq	301	16	,	,	,
cord-010027-r0tl01kq	301	17	their	-PRON-	PRP$
cord-010027-r0tl01kq	301	18	results	result	NNS
cord-010027-r0tl01kq	301	19	clearly	clearly	RB
cord-010027-r0tl01kq	301	20	indicate	indicate	VBP
cord-010027-r0tl01kq	301	21	the	the	DT
cord-010027-r0tl01kq	301	22	need	need	NN
cord-010027-r0tl01kq	301	23	for	for	IN
cord-010027-r0tl01kq	301	24	EQA	eqa	NN
cord-010027-r0tl01kq	301	25	since	since	IN
cord-010027-r0tl01kq	301	26	10%-15	10%-15	CD
cord-010027-r0tl01kq	301	27	%	%	NN
cord-010027-r0tl01kq	301	28	of	of	IN
cord-010027-r0tl01kq	301	29	laboratories	laboratory	NNS
cord-010027-r0tl01kq	301	30	do	do	VBP
cord-010027-r0tl01kq	301	31	not	not	RB
cord-010027-r0tl01kq	301	32	carry	carry	VB
cord-010027-r0tl01kq	301	33	out	out	RP
cord-010027-r0tl01kq	301	34	according	accord	VBG
cord-010027-r0tl01kq	301	35	to	to	IN
cord-010027-r0tl01kq	301	36	the	the	DT
cord-010027-r0tl01kq	301	37	standard	standard	JJ
cord-010027-r0tl01kq	301	38	set	set	VBN
cord-010027-r0tl01kq	301	39	by	by	IN
cord-010027-r0tl01kq	301	40	the	the	DT
cord-010027-r0tl01kq	301	41	EQA	EQA	NNP
cord-010027-r0tl01kq	301	42	provider	provider	NN
cord-010027-r0tl01kq	301	43	or	or	CC
cord-010027-r0tl01kq	301	44	utilize	utilize	VB
cord-010027-r0tl01kq	301	45	standardized	standardized	JJ
cord-010027-r0tl01kq	301	46	procedures	procedure	NNS
cord-010027-r0tl01kq	301	47	.	.	.
cord-010027-r0tl01kq	302	1	Continual	continual	JJ
cord-010027-r0tl01kq	302	2	improvement	improvement	NN
cord-010027-r0tl01kq	302	3	programs	program	NNS
cord-010027-r0tl01kq	302	4	,	,	,
cord-010027-r0tl01kq	302	5	internal	internal	JJ
cord-010027-r0tl01kq	302	6	quality	quality	NN
cord-010027-r0tl01kq	302	7	control	control	NN
cord-010027-r0tl01kq	302	8	and	and	CC
cord-010027-r0tl01kq	302	9	validation	validation	NN
cord-010027-r0tl01kq	302	10	program	program	NN
cord-010027-r0tl01kq	302	11	assist	assist	VBP
cord-010027-r0tl01kq	302	12	laboratories	laboratory	NNS
cord-010027-r0tl01kq	302	13	however	however	RB
cord-010027-r0tl01kq	302	14	;	;	:
cord-010027-r0tl01kq	302	15	by	by	IN
cord-010027-r0tl01kq	302	16	using	use	VBG
cord-010027-r0tl01kq	302	17	standardized	standardized	JJ
cord-010027-r0tl01kq	302	18	quality	quality	NN
cord-010027-r0tl01kq	302	19	practices	practice	NNS
cord-010027-r0tl01kq	302	20	such	such	JJ
cord-010027-r0tl01kq	302	21	as	as	IN
cord-010027-r0tl01kq	302	22	ISO	iso	NN
cord-010027-r0tl01kq	302	23	15189	15189	CD
cord-010027-r0tl01kq	302	24	and	and	CC
cord-010027-r0tl01kq	302	25	the	the	DT
cord-010027-r0tl01kq	302	26	use	use	NN
cord-010027-r0tl01kq	302	27	of	of	IN
cord-010027-r0tl01kq	302	28	external	external	JJ
cord-010027-r0tl01kq	302	29	quality	quality	NN
cord-010027-r0tl01kq	302	30	assurance	assurance	NN
cord-010027-r0tl01kq	302	31	schemes	scheme	NNS
cord-010027-r0tl01kq	302	32	can	can	MD
cord-010027-r0tl01kq	302	33	provide	provide	VB
cord-010027-r0tl01kq	302	34	essential	essential	JJ
cord-010027-r0tl01kq	302	35	feedback	feedback	NN
cord-010027-r0tl01kq	302	36	to	to	IN
cord-010027-r0tl01kq	302	37	the	the	DT
cord-010027-r0tl01kq	302	38	laboratory	laboratory	NN
cord-010027-r0tl01kq	302	39	to	to	TO
cord-010027-r0tl01kq	302	40	assure	assure	VB
cord-010027-r0tl01kq	302	41	accurate	accurate	JJ
cord-010027-r0tl01kq	302	42	molecular	molecular	JJ
cord-010027-r0tl01kq	302	43	testing	testing	NN
cord-010027-r0tl01kq	302	44	results	result	NNS
cord-010027-r0tl01kq	302	45	.	.	.
cord-010027-r0tl01kq	303	1			,
cord-010027-r0tl01kq	303	2	How	how	WRB
cord-010027-r0tl01kq	303	3	to	to	TO
cord-010027-r0tl01kq	303	4	Run	run	VB
cord-010027-r0tl01kq	303	5	a	a	DT
cord-010027-r0tl01kq	303	6	Histopathology	Histopathology	NNP
cord-010027-r0tl01kq	303	7	EQA	EQA	NNP
cord-010027-r0tl01kq	303	8	in	in	IN
cord-010027-r0tl01kq	303	9	the	the	DT
cord-010027-r0tl01kq	303	10	Digital	Digital	NNP
cord-010027-r0tl01kq	303	11	Age	Age	NNP
cord-010027-r0tl01kq	303	12	P	P	NNP
cord-010027-r0tl01kq	303	13	NJ	NJ	NNP
cord-010027-r0tl01kq	303	14	Mayer	Mayer	NNP
cord-010027-r0tl01kq	303	15	1	1	CD
cord-010027-r0tl01kq	303	16	;	;	:
cord-010027-r0tl01kq	303	17	P	P	NNP
cord-010027-r0tl01kq	303	18	JD	JD	NNP
cord-010027-r0tl01kq	303	19	Oxley	Oxley	NNP
cord-010027-r0tl01kq	303	20	2	2	CD
cord-010027-r0tl01kq	303	21	1	1	CD
cord-010027-r0tl01kq	303	22	Cork	Cork	NNP
cord-010027-r0tl01kq	303	23	University	University	NNP
cord-010027-r0tl01kq	303	24	Hospital	Hospital	NNP
cord-010027-r0tl01kq	303	25	,	,	,
cord-010027-r0tl01kq	303	26	Cork	Cork	NNP
cord-010027-r0tl01kq	303	27	,	,	,
cord-010027-r0tl01kq	303	28	Ireland	Ireland	NNP
cord-010027-r0tl01kq	303	29	;	;	:
cord-010027-r0tl01kq	303	30	2	2	CD
cord-010027-r0tl01kq	303	31	Southmead	Southmead	NNP
cord-010027-r0tl01kq	303	32	Hospital	Hospital	NNP
cord-010027-r0tl01kq	303	33	,	,	,
cord-010027-r0tl01kq	303	34	Bristol	Bristol	NNP
cord-010027-r0tl01kq	303	35	,	,	,
cord-010027-r0tl01kq	303	36	UK	UK	NNP
cord-010027-r0tl01kq	303	37	Interpretative	Interpretative	NNP
cord-010027-r0tl01kq	303	38	EQA	EQA	NNP
cord-010027-r0tl01kq	303	39	schemes	scheme	NNS
cord-010027-r0tl01kq	303	40	in	in	IN
cord-010027-r0tl01kq	303	41	Histopathology	Histopathology	NNP
cord-010027-r0tl01kq	303	42	were	be	VBD
cord-010027-r0tl01kq	303	43	first	first	RB
cord-010027-r0tl01kq	303	44	introduced	introduce	VBN
cord-010027-r0tl01kq	303	45	in	in	IN
cord-010027-r0tl01kq	303	46	the	the	DT
cord-010027-r0tl01kq	303	47	UK	UK	NNP
cord-010027-r0tl01kq	303	48	in	in	IN
cord-010027-r0tl01kq	303	49	the	the	DT
cord-010027-r0tl01kq	303	50	mid-1980s	mid-1980	NNS
cord-010027-r0tl01kq	303	51	,	,	,
cord-010027-r0tl01kq	303	52	well	well	RB
cord-010027-r0tl01kq	303	53	before	before	IN
cord-010027-r0tl01kq	303	54	the	the	DT
cord-010027-r0tl01kq	303	55	advent	advent	NN
cord-010027-r0tl01kq	303	56	of	of	IN
cord-010027-r0tl01kq	303	57	the	the	DT
cord-010027-r0tl01kq	303	58	Internet	internet	NN
cord-010027-r0tl01kq	303	59	and	and	CC
cord-010027-r0tl01kq	303	60	high	high	JJ
cord-010027-r0tl01kq	303	61	resolution	resolution	NN
cord-010027-r0tl01kq	303	62	digital	digital	JJ
cord-010027-r0tl01kq	303	63	images	image	NNS
cord-010027-r0tl01kq	303	64	.	.	.
cord-010027-r0tl01kq	304	1	In	in	IN
cord-010027-r0tl01kq	304	2	this	this	DT
cord-010027-r0tl01kq	304	3	lecture	lecture	NN
cord-010027-r0tl01kq	304	4	we	-PRON-	PRP
cord-010027-r0tl01kq	304	5	will	will	MD
cord-010027-r0tl01kq	304	6	outline	outline	VB
cord-010027-r0tl01kq	304	7	key	key	JJ
cord-010027-r0tl01kq	304	8	developments	development	NNS
cord-010027-r0tl01kq	304	9	,	,	,
cord-010027-r0tl01kq	304	10	as	as	IN
cord-010027-r0tl01kq	304	11	EQA	EQA	NNP
cord-010027-r0tl01kq	304	12	schemes	scheme	NNS
cord-010027-r0tl01kq	304	13	have	have	VBP
cord-010027-r0tl01kq	304	14	evolved	evolve	VBN
cord-010027-r0tl01kq	304	15	into	into	IN
cord-010027-r0tl01kq	304	16	the	the	DT
cord-010027-r0tl01kq	304	17	digital	digital	JJ
cord-010027-r0tl01kq	304	18	era	era	NN
cord-010027-r0tl01kq	304	19	,	,	,
cord-010027-r0tl01kq	304	20	with	with	IN
cord-010027-r0tl01kq	304	21	particular	particular	JJ
cord-010027-r0tl01kq	304	22	emphasis	emphasis	NN
cord-010027-r0tl01kq	304	23	on	on	IN
cord-010027-r0tl01kq	304	24	the	the	DT
cord-010027-r0tl01kq	304	25	National	National	NNP
cord-010027-r0tl01kq	304	26	Urological	Urological	NNP
cord-010027-r0tl01kq	304	27	EQA	EQA	NNP
cord-010027-r0tl01kq	304	28	scheme	scheme	NN
cord-010027-r0tl01kq	304	29	,	,	,
cord-010027-r0tl01kq	304	30	which	which	WDT
cord-010027-r0tl01kq	304	31	we	-PRON-	PRP
cord-010027-r0tl01kq	304	32	have	have	VBP
cord-010027-r0tl01kq	304	33	run	run	VBN
cord-010027-r0tl01kq	304	34	since	since	IN
cord-010027-r0tl01kq	304	35	2007	2007	CD
cord-010027-r0tl01kq	304	36	.	.	.
cord-010027-r0tl01kq	305	1	We	-PRON-	PRP
cord-010027-r0tl01kq	305	2	will	will	MD
cord-010027-r0tl01kq	305	3	outline	outline	VB
cord-010027-r0tl01kq	305	4	the	the	DT
cord-010027-r0tl01kq	305	5	main	main	JJ
cord-010027-r0tl01kq	305	6	practical	practical	JJ
cord-010027-r0tl01kq	305	7	issues	issue	NNS
cord-010027-r0tl01kq	305	8	involved	involve	VBN
cord-010027-r0tl01kq	305	9	in	in	IN
cord-010027-r0tl01kq	305	10	running	run	VBG
cord-010027-r0tl01kq	305	11	an	an	DT
cord-010027-r0tl01kq	305	12	EQA	eqa	NN
cord-010027-r0tl01kq	305	13	scheme	scheme	NN
cord-010027-r0tl01kq	305	14	and	and	CC
cord-010027-r0tl01kq	305	15	share	share	VB
cord-010027-r0tl01kq	305	16	our	-PRON-	PRP$
cord-010027-r0tl01kq	305	17	personal	personal	JJ
cord-010027-r0tl01kq	305	18	experience	experience	NN
cord-010027-r0tl01kq	305	19	of	of	IN
cord-010027-r0tl01kq	305	20	the	the	DT
cord-010027-r0tl01kq	305	21	development	development	NN
cord-010027-r0tl01kq	305	22	and	and	CC
cord-010027-r0tl01kq	305	23	introduction	introduction	NN
cord-010027-r0tl01kq	305	24	of	of	IN
cord-010027-r0tl01kq	305	25	the	the	DT
cord-010027-r0tl01kq	305	26	web	web	NN
cord-010027-r0tl01kq	305	27	-	-	HYPH
cord-010027-r0tl01kq	305	28	based	base	VBN
cord-010027-r0tl01kq	305	29	EQAlite	EQAlite	NNP
cord-010027-r0tl01kq	305	30	software	software	NN
cord-010027-r0tl01kq	305	31	,	,	,
cord-010027-r0tl01kq	305	32	which	which	WDT
cord-010027-r0tl01kq	305	33	is	be	VBZ
cord-010027-r0tl01kq	305	34	being	be	VBG
cord-010027-r0tl01kq	305	35	utilised	utilise	VBN
cord-010027-r0tl01kq	305	36	by	by	IN
cord-010027-r0tl01kq	305	37	increasing	increase	VBG
cord-010027-r0tl01kq	305	38	numbers	number	NNS
cord-010027-r0tl01kq	305	39	of	of	IN
cord-010027-r0tl01kq	305	40	schemes	scheme	NNS
cord-010027-r0tl01kq	305	41	.	.	.
cord-010027-r0tl01kq	306	1	We	-PRON-	PRP
cord-010027-r0tl01kq	306	2	will	will	MD
cord-010027-r0tl01kq	306	3	address	address	VB
cord-010027-r0tl01kq	306	4	the	the	DT
cord-010027-r0tl01kq	306	5	pros	pro	NNS
cord-010027-r0tl01kq	306	6	and	and	CC
cord-010027-r0tl01kq	306	7	cons	con	NNS
cord-010027-r0tl01kq	306	8	of	of	IN
cord-010027-r0tl01kq	306	9	traditional	traditional	JJ
cord-010027-r0tl01kq	306	10	glass	glass	NN
cord-010027-r0tl01kq	306	11	slide	slide	NN
cord-010027-r0tl01kq	306	12	-	-	HYPH
cord-010027-r0tl01kq	306	13	based	base	VBN
cord-010027-r0tl01kq	306	14	circulations	circulation	NNS
cord-010027-r0tl01kq	306	15	versus	versus	IN
cord-010027-r0tl01kq	306	16	virtual	virtual	JJ
cord-010027-r0tl01kq	306	17	circulations	circulation	NNS
cord-010027-r0tl01kq	306	18	using	use	VBG
cord-010027-r0tl01kq	306	19	scanned	scan	VBN
cord-010027-r0tl01kq	306	20	digital	digital	JJ
cord-010027-r0tl01kq	306	21	images	image	NNS
cord-010027-r0tl01kq	306	22	and	and	CC
cord-010027-r0tl01kq	306	23	show	show	VB
cord-010027-r0tl01kq	306	24	how	how	WRB
cord-010027-r0tl01kq	306	25	the	the	DT
cord-010027-r0tl01kq	306	26	digital	digital	JJ
cord-010027-r0tl01kq	306	27	archive	archive	NN
cord-010027-r0tl01kq	306	28	generated	generate	VBN
cord-010027-r0tl01kq	306	29	from	from	IN
cord-010027-r0tl01kq	306	30	old	old	JJ
cord-010027-r0tl01kq	306	31	EQA	EQA	NNP
cord-010027-r0tl01kq	306	32	circulations	circulation	NNS
cord-010027-r0tl01kq	306	33	has	have	VBZ
cord-010027-r0tl01kq	306	34	become	become	VBN
cord-010027-r0tl01kq	306	35	a	a	DT
cord-010027-r0tl01kq	306	36	valuable	valuable	JJ
cord-010027-r0tl01kq	306	37	educational	educational	JJ
cord-010027-r0tl01kq	306	38	and	and	CC
cord-010027-r0tl01kq	306	39	teaching	teaching	NN
cord-010027-r0tl01kq	306	40	resource	resource	NN
cord-010027-r0tl01kq	306	41	.	.	.
cord-010027-r0tl01kq	307	1	We	-PRON-	PRP
cord-010027-r0tl01kq	307	2	will	will	MD
cord-010027-r0tl01kq	307	3	also	also	RB
cord-010027-r0tl01kq	307	4	briefly	briefly	RB
cord-010027-r0tl01kq	307	5	explore	explore	VB
cord-010027-r0tl01kq	307	6	,	,	,
cord-010027-r0tl01kq	307	7	from	from	IN
cord-010027-r0tl01kq	307	8	an	an	DT
cord-010027-r0tl01kq	307	9	Organiser	Organiser	NNP
cord-010027-r0tl01kq	307	10	's	's	POS
cord-010027-r0tl01kq	307	11	perspective	perspective	NN
cord-010027-r0tl01kq	307	12	,	,	,
cord-010027-r0tl01kq	307	13	the	the	DT
cord-010027-r0tl01kq	307	14	major	major	JJ
cord-010027-r0tl01kq	307	15	issues	issue	NNS
cord-010027-r0tl01kq	307	16	facing	face	VBG
cord-010027-r0tl01kq	307	17	EQA	EQA	NNP
cord-010027-r0tl01kq	307	18	schemes	scheme	NNS
cord-010027-r0tl01kq	307	19	in	in	IN
cord-010027-r0tl01kq	307	20	the	the	DT
cord-010027-r0tl01kq	307	21	future	future	NN
cord-010027-r0tl01kq	307	22	,	,	,
cord-010027-r0tl01kq	307	23	as	as	IN
cord-010027-r0tl01kq	307	24	EQA	EQA	NNP
cord-010027-r0tl01kq	307	25	performance	performance	NN
cord-010027-r0tl01kq	307	26	becomes	become	VBZ
cord-010027-r0tl01kq	307	27	more	more	RBR
cord-010027-r0tl01kq	307	28	embedded	embed	VBN
cord-010027-r0tl01kq	307	29	into	into	IN
cord-010027-r0tl01kq	307	30	revalidation	revalidation	NN
cord-010027-r0tl01kq	307	31	and	and	CC
cord-010027-r0tl01kq	307	32	fitness	fitness	NN
cord-010027-r0tl01kq	307	33	to	to	TO
cord-010027-r0tl01kq	307	34	practice	practice	VB
cord-010027-r0tl01kq	307	35	.	.	.
cord-010027-r0tl01kq	308	1			NFP
cord-010027-r0tl01kq	308	2	Molecular	Molecular	NNP
cord-010027-r0tl01kq	308	3	Pathology	Pathology	NNP
cord-010027-r0tl01kq	308	4	:	:	:
cord-010027-r0tl01kq	308	5	The	the	DT
cord-010027-r0tl01kq	308	6	Future	Future	NNP
cord-010027-r0tl01kq	308	7	?	?	.
cord-010027-r0tl01kq	309	1	P	p	NN
cord-010027-r0tl01kq	309	2	CS	CS	NNP
cord-010027-r0tl01kq	309	3	Herrington	Herrington	NNP
cord-010027-r0tl01kq	309	4	Molecular	Molecular	NNP
cord-010027-r0tl01kq	309	5	pathology	pathology	NN
cord-010027-r0tl01kq	309	6	is	be	VBZ
cord-010027-r0tl01kq	309	7	already	already	RB
cord-010027-r0tl01kq	309	8	central	central	JJ
cord-010027-r0tl01kq	309	9	to	to	IN
cord-010027-r0tl01kq	309	10	stratified	stratified	JJ
cord-010027-r0tl01kq	309	11	medicine	medicine	NN
cord-010027-r0tl01kq	309	12	.	.	.
cord-010027-r0tl01kq	310	1	And	and	CC
cord-010027-r0tl01kq	310	2	the	the	DT
cord-010027-r0tl01kq	310	3	ability	ability	NN
cord-010027-r0tl01kq	310	4	of	of	IN
cord-010027-r0tl01kq	310	5	pathologists	pathologist	NNS
cord-010027-r0tl01kq	310	6	to	to	TO
cord-010027-r0tl01kq	310	7	understand	understand	VB
cord-010027-r0tl01kq	310	8	disease	disease	NN
cord-010027-r0tl01kq	310	9	phenotype	phenotype	NN
cord-010027-r0tl01kq	310	10	is	be	VBZ
cord-010027-r0tl01kq	310	11	essential	essential	JJ
cord-010027-r0tl01kq	310	12	for	for	IN
cord-010027-r0tl01kq	310	13	interpretation	interpretation	NN
cord-010027-r0tl01kq	310	14	of	of	IN
cord-010027-r0tl01kq	310	15	the	the	DT
cord-010027-r0tl01kq	310	16	current	current	JJ
cord-010027-r0tl01kq	310	17	explosion	explosion	NN
cord-010027-r0tl01kq	310	18	in	in	IN
cord-010027-r0tl01kq	310	19	'	'	``
cord-010027-r0tl01kq	310	20	-omics	-omic	NNS
cord-010027-r0tl01kq	310	21	'	'	POS
cord-010027-r0tl01kq	310	22	data	datum	NNS
cord-010027-r0tl01kq	310	23	.	.	.
cord-010027-r0tl01kq	311	1	Moreover	moreover	RB
cord-010027-r0tl01kq	311	2	,	,	,
cord-010027-r0tl01kq	311	3	the	the	DT
cord-010027-r0tl01kq	311	4	future	future	NN
cord-010027-r0tl01kq	311	5	of	of	IN
cord-010027-r0tl01kq	311	6	stratified	stratified	JJ
cord-010027-r0tl01kq	311	7	medicine	medicine	NN
cord-010027-r0tl01kq	311	8	will	will	MD
cord-010027-r0tl01kq	311	9	require	require	VB
cord-010027-r0tl01kq	311	10	integration	integration	NN
cord-010027-r0tl01kq	311	11	of	of	IN
cord-010027-r0tl01kq	311	12	information	information	NN
cord-010027-r0tl01kq	311	13	from	from	IN
cord-010027-r0tl01kq	311	14	different	different	JJ
cord-010027-r0tl01kq	311	15	sources	source	NNS
cord-010027-r0tl01kq	311	16	,	,	,
cord-010027-r0tl01kq	311	17	in	in	IN
cord-010027-r0tl01kq	311	18	the	the	DT
cord-010027-r0tl01kq	311	19	context	context	NN
cord-010027-r0tl01kq	311	20	of	of	IN
cord-010027-r0tl01kq	311	21	disease	disease	NN
cord-010027-r0tl01kq	311	22	phenotype	phenotype	NN
cord-010027-r0tl01kq	311	23	,	,	,
cord-010027-r0tl01kq	311	24	to	to	TO
cord-010027-r0tl01kq	311	25	inform	inform	VB
cord-010027-r0tl01kq	311	26	patient	patient	JJ
cord-010027-r0tl01kq	311	27	management	management	NN
cord-010027-r0tl01kq	311	28	:	:	:
cord-010027-r0tl01kq	311	29	pathologists	pathologist	NNS
cord-010027-r0tl01kq	311	30	are	be	VBP
cord-010027-r0tl01kq	311	31	ideally	ideally	RB
cord-010027-r0tl01kq	311	32	placed	place	VBN
cord-010027-r0tl01kq	311	33	to	to	TO
cord-010027-r0tl01kq	311	34	lead	lead	VB
cord-010027-r0tl01kq	311	35	this	this	DT
cord-010027-r0tl01kq	311	36	integration	integration	NN
cord-010027-r0tl01kq	311	37	.	.	.
cord-010027-r0tl01kq	312	1	This	this	DT
cord-010027-r0tl01kq	312	2	applies	apply	VBZ
cord-010027-r0tl01kq	312	3	not	not	RB
cord-010027-r0tl01kq	312	4	only	only	RB
cord-010027-r0tl01kq	312	5	to	to	IN
cord-010027-r0tl01kq	312	6	data	datum	NNS
cord-010027-r0tl01kq	312	7	derived	derive	VBN
cord-010027-r0tl01kq	312	8	from	from	IN
cord-010027-r0tl01kq	312	9	ex	ex	NNP
cord-010027-r0tl01kq	312	10	vivo	vivo	NN
cord-010027-r0tl01kq	312	11	cells	cell	NNS
cord-010027-r0tl01kq	312	12	and	and	CC
cord-010027-r0tl01kq	312	13	tissues	tissue	NNS
cord-010027-r0tl01kq	312	14	but	but	CC
cord-010027-r0tl01kq	312	15	also	also	RB
cord-010027-r0tl01kq	312	16	to	to	IN
cord-010027-r0tl01kq	312	17	molecular	molecular	JJ
cord-010027-r0tl01kq	312	18	imaging	imaging	NN
cord-010027-r0tl01kq	312	19	data	datum	NNS
cord-010027-r0tl01kq	312	20	,	,	,
cord-010027-r0tl01kq	312	21	which	which	WDT
cord-010027-r0tl01kq	312	22	require	require	VBP
cord-010027-r0tl01kq	312	23	accurate	accurate	JJ
cord-010027-r0tl01kq	312	24	correlation	correlation	NN
cord-010027-r0tl01kq	312	25	with	with	IN
cord-010027-r0tl01kq	312	26	cell	cell	NN
cord-010027-r0tl01kq	312	27	and	and	CC
cord-010027-r0tl01kq	312	28	tissue	tissue	NN
cord-010027-r0tl01kq	312	29	phenotype	phenotype	NN
cord-010027-r0tl01kq	312	30	for	for	IN
cord-010027-r0tl01kq	312	31	accurate	accurate	JJ
cord-010027-r0tl01kq	312	32	interpretation	interpretation	NN
cord-010027-r0tl01kq	312	33	.	.	.
cord-010027-r0tl01kq	313	1	Molecular	molecular	JJ
cord-010027-r0tl01kq	313	2	pathology	pathology	NN
cord-010027-r0tl01kq	313	3	is	be	VBZ
cord-010027-r0tl01kq	313	4	key	key	JJ
cord-010027-r0tl01kq	313	5	to	to	IN
cord-010027-r0tl01kq	313	6	the	the	DT
cord-010027-r0tl01kq	313	7	future	future	NN
cord-010027-r0tl01kq	313	8	of	of	IN
cord-010027-r0tl01kq	313	9	pathology	pathology	NN
cord-010027-r0tl01kq	313	10	;	;	:
cord-010027-r0tl01kq	313	11	and	and	CC
cord-010027-r0tl01kq	313	12	this	this	DT
cord-010027-r0tl01kq	313	13	future	future	NN
cord-010027-r0tl01kq	313	14	extends	extend	VBZ
cord-010027-r0tl01kq	313	15	beyond	beyond	IN
cord-010027-r0tl01kq	313	16	the	the	DT
cord-010027-r0tl01kq	313	17	traditional	traditional	JJ
cord-010027-r0tl01kq	313	18	light	light	JJ
cord-010027-r0tl01kq	313	19	microscope	microscope	NN
cord-010027-r0tl01kq	314	1	The	the	DT
cord-010027-r0tl01kq	314	2	following	follow	VBG
cord-010027-r0tl01kq	314	3	Plenary	Plenary	NNP
cord-010027-r0tl01kq	314	4	,	,	,
cord-010027-r0tl01kq	314	5	Oral	oral	JJ
cord-010027-r0tl01kq	314	6	and	and	CC
cord-010027-r0tl01kq	314	7	Poster	poster	NN
cord-010027-r0tl01kq	314	8	abstracts	abstract	NNS
cord-010027-r0tl01kq	314	9	have	have	VBP
cord-010027-r0tl01kq	314	10	been	be	VBN
cord-010027-r0tl01kq	314	11	subjected	subject	VBN
cord-010027-r0tl01kq	314	12	to	to	IN
cord-010027-r0tl01kq	314	13	peer	peer	NN
cord-010027-r0tl01kq	314	14	review	review	NN
cord-010027-r0tl01kq	314	15	.	.	.
cord-010027-r0tl01kq	315	1	Hypothesis	hypothesis	NN
cord-010027-r0tl01kq	315	2	:	:	:
cord-010027-r0tl01kq	315	3	Suppressor	suppressor	NN
cord-010027-r0tl01kq	315	4	of	of	IN
cord-010027-r0tl01kq	315	5	cytokine	cytokine	NN
cord-010027-r0tl01kq	315	6	signalling	signalling	NN
cord-010027-r0tl01kq	316	1	(	(	-LRB-
cord-010027-r0tl01kq	316	2	SOCS	SOCS	NNP
cord-010027-r0tl01kq	316	3	)	)	-RRB-
cord-010027-r0tl01kq	316	4	family	family	NN
cord-010027-r0tl01kq	316	5	members	member	NNS
cord-010027-r0tl01kq	316	6	play	play	VBP
cord-010027-r0tl01kq	316	7	a	a	DT
cord-010027-r0tl01kq	316	8	vital	vital	JJ
cord-010027-r0tl01kq	316	9	role	role	NN
cord-010027-r0tl01kq	316	10	in	in	IN
cord-010027-r0tl01kq	316	11	the	the	DT
cord-010027-r0tl01kq	316	12	activation	activation	NN
cord-010027-r0tl01kq	316	13	of	of	IN
cord-010027-r0tl01kq	316	14	the	the	DT
cord-010027-r0tl01kq	316	15	JAK	JAK	NNP
cord-010027-r0tl01kq	316	16	/	/	SYM
cord-010027-r0tl01kq	316	17	STAT	STAT	NNP
cord-010027-r0tl01kq	316	18	signalling	signal	VBG
cord-010027-r0tl01kq	316	19	pathway	pathway	NN
cord-010027-r0tl01kq	316	20	via	via	IN
cord-010027-r0tl01kq	316	21	a	a	DT
cord-010027-r0tl01kq	316	22	negative	negative	JJ
cord-010027-r0tl01kq	316	23	feedback	feedback	NN
cord-010027-r0tl01kq	316	24	loop	loop	NN
cord-010027-r0tl01kq	316	25	and	and	CC
cord-010027-r0tl01kq	316	26	have	have	VBP
cord-010027-r0tl01kq	316	27	been	be	VBN
cord-010027-r0tl01kq	316	28	implicated	implicate	VBN
cord-010027-r0tl01kq	316	29	in	in	IN
cord-010027-r0tl01kq	316	30	the	the	DT
cord-010027-r0tl01kq	316	31	development	development	NN
cord-010027-r0tl01kq	316	32	of	of	IN
cord-010027-r0tl01kq	316	33	cancers	cancer	NNS
cord-010027-r0tl01kq	316	34	.	.	.
cord-010027-r0tl01kq	317	1	In	in	IN
cord-010027-r0tl01kq	317	2	breast	breast	NN
cord-010027-r0tl01kq	317	3	cancer	cancer	NN
cord-010027-r0tl01kq	317	4	(	(	-LRB-
cord-010027-r0tl01kq	317	5	BC	BC	NNP
cord-010027-r0tl01kq	317	6	)	)	-RRB-
cord-010027-r0tl01kq	317	7	,	,	,
cord-010027-r0tl01kq	317	8	SOCS2	SOCS2	NNP
cord-010027-r0tl01kq	317	9	mRNA	mRNA	NNP
cord-010027-r0tl01kq	317	10	has	have	VBZ
cord-010027-r0tl01kq	317	11	been	be	VBN
cord-010027-r0tl01kq	317	12	correlated	correlate	VBN
cord-010027-r0tl01kq	317	13	with	with	IN
cord-010027-r0tl01kq	317	14	oestrogen	oestrogen	NN
cord-010027-r0tl01kq	317	15	receptor	receptor	NN
cord-010027-r0tl01kq	317	16	(	(	-LRB-
cord-010027-r0tl01kq	317	17	ER	ER	NNP
cord-010027-r0tl01kq	317	18	)	)	-RRB-
cord-010027-r0tl01kq	317	19	positive	positive	JJ
cord-010027-r0tl01kq	317	20	tumours	tumour	NNS
cord-010027-r0tl01kq	317	21	favouring	favour	VBG
cord-010027-r0tl01kq	317	22	a	a	DT
cord-010027-r0tl01kq	317	23	good	good	JJ
cord-010027-r0tl01kq	317	24	prognosis	prognosis	NN
cord-010027-r0tl01kq	317	25	(	(	-LRB-
cord-010027-r0tl01kq	317	26	BMC	BMC	NNP
cord-010027-r0tl01kq	317	27	Cancer	Cancer	NNP
cord-010027-r0tl01kq	317	28	2007	2007	CD
cord-010027-r0tl01kq	317	29	,	,	,
cord-010027-r0tl01kq	317	30	7:136	7:136	CD
cord-010027-r0tl01kq	317	31	)	)	-RRB-
cord-010027-r0tl01kq	317	32	.	.	.
cord-010027-r0tl01kq	318	1	This	this	DT
cord-010027-r0tl01kq	318	2	study	study	NN
cord-010027-r0tl01kq	318	3	aimed	aim	VBD
cord-010027-r0tl01kq	318	4	to	to	TO
cord-010027-r0tl01kq	318	5	determine	determine	VB
cord-010027-r0tl01kq	318	6	whether	whether	IN
cord-010027-r0tl01kq	318	7	SOCS2	socs2	NN
cord-010027-r0tl01kq	318	8	at	at	IN
cord-010027-r0tl01kq	318	9	the	the	DT
cord-010027-r0tl01kq	318	10	protein	protein	NN
cord-010027-r0tl01kq	318	11	level	level	NN
cord-010027-r0tl01kq	318	12	correlates	correlate	VBZ
cord-010027-r0tl01kq	318	13	with	with	IN
cord-010027-r0tl01kq	318	14	tumour	tumour	NN
cord-010027-r0tl01kq	318	15	morphology	morphology	NN
cord-010027-r0tl01kq	318	16	and	and	CC
cord-010027-r0tl01kq	318	17	low	low	JJ
cord-010027-r0tl01kq	318	18	grade	grade	NN
cord-010027-r0tl01kq	318	19	in	in	IN
cord-010027-r0tl01kq	318	20	BC	BC	NNP
cord-010027-r0tl01kq	318	21	.	.	.
cord-010027-r0tl01kq	319	1	Methods	method	NNS
cord-010027-r0tl01kq	319	2	:	:	:
cord-010027-r0tl01kq	319	3	Differential	differential	JJ
cord-010027-r0tl01kq	319	4	expression	expression	NN
cord-010027-r0tl01kq	319	5	analysis	analysis	NN
cord-010027-r0tl01kq	319	6	between	between	IN
cord-010027-r0tl01kq	319	7	tubular	tubular	JJ
cord-010027-r0tl01kq	319	8	and	and	CC
cord-010027-r0tl01kq	319	9	grade	grade	NN
cord-010027-r0tl01kq	319	10	matched	match	VBN
cord-010027-r0tl01kq	319	11	NSTs	nst	NNS
cord-010027-r0tl01kq	319	12	were	be	VBD
cord-010027-r0tl01kq	319	13	undertaken	undertake	VBN
cord-010027-r0tl01kq	319	14	in	in	IN
cord-010027-r0tl01kq	319	15	the	the	DT
cord-010027-r0tl01kq	319	16	METABRIC	METABRIC	NNP
cord-010027-r0tl01kq	319	17	cohort	cohort	NN
cord-010027-r0tl01kq	319	18	.	.	.
cord-010027-r0tl01kq	320	1	Primary	primary	JJ
cord-010027-r0tl01kq	320	2	breast	breast	NN
cord-010027-r0tl01kq	320	3	cancer	cancer	NN
cord-010027-r0tl01kq	320	4	tissue	tissue	NN
cord-010027-r0tl01kq	320	5	microarrays	microarray	NNS
cord-010027-r0tl01kq	320	6	(	(	-LRB-
cord-010027-r0tl01kq	320	7	n=1041	n=1041	CD
cord-010027-r0tl01kq	320	8	)	)	-RRB-
cord-010027-r0tl01kq	320	9	were	be	VBD
cord-010027-r0tl01kq	320	10	immuno	immuno	JJ
cord-010027-r0tl01kq	320	11	-	-	HYPH
cord-010027-r0tl01kq	320	12	stained	stained	JJ
cord-010027-r0tl01kq	320	13	for	for	IN
cord-010027-r0tl01kq	320	14	SOCS2	socs2	NN
cord-010027-r0tl01kq	320	15	and	and	CC
cord-010027-r0tl01kq	320	16	expression	expression	NN
cord-010027-r0tl01kq	320	17	patterns	pattern	NNS
cord-010027-r0tl01kq	320	18	correlated	correlate	VBN
cord-010027-r0tl01kq	320	19	with	with	IN
cord-010027-r0tl01kq	320	20	clinico	clinico	NN
cord-010027-r0tl01kq	320	21	-	-	HYPH
cord-010027-r0tl01kq	320	22	pathological	pathological	JJ
cord-010027-r0tl01kq	320	23	and	and	CC
cord-010027-r0tl01kq	320	24	molecular	molecular	JJ
cord-010027-r0tl01kq	320	25	variables	variable	NNS
cord-010027-r0tl01kq	320	26	including	include	VBG
cord-010027-r0tl01kq	320	27	outcome	outcome	NN
cord-010027-r0tl01kq	320	28	.	.	.
cord-010027-r0tl01kq	321	1	Results	result	NNS
cord-010027-r0tl01kq	321	2	:	:	:
cord-010027-r0tl01kq	322	1	Differential	differential	JJ
cord-010027-r0tl01kq	322	2	gene	gene	NN
cord-010027-r0tl01kq	322	3	expression	expression	NN
cord-010027-r0tl01kq	322	4	analysis	analysis	NN
cord-010027-r0tl01kq	322	5	on	on	IN
cord-010027-r0tl01kq	322	6	the	the	DT
cord-010027-r0tl01kq	322	7	METABRIC	METABRIC	NNP
cord-010027-r0tl01kq	322	8	data	datum	NNS
cord-010027-r0tl01kq	322	9	identified	identify	VBD
cord-010027-r0tl01kq	322	10	SOCS2	socs2	NN
cord-010027-r0tl01kq	322	11	as	as	IN
cord-010027-r0tl01kq	322	12	the	the	DT
cord-010027-r0tl01kq	322	13	top	top	JJ
cord-010027-r0tl01kq	322	14	gene	gene	NN
cord-010027-r0tl01kq	322	15	with	with	IN
cord-010027-r0tl01kq	322	16	a	a	DT
cord-010027-r0tl01kq	322	17	significant	significant	JJ
cord-010027-r0tl01kq	322	18	overexpression	overexpression	NN
cord-010027-r0tl01kq	322	19	in	in	IN
cord-010027-r0tl01kq	322	20	the	the	DT
cord-010027-r0tl01kq	322	21	tubular	tubular	JJ
cord-010027-r0tl01kq	322	22	type	type	NN
cord-010027-r0tl01kq	322	23	as	as	IN
cord-010027-r0tl01kq	322	24	compared	compare	VBN
cord-010027-r0tl01kq	322	25	to	to	IN
cord-010027-r0tl01kq	322	26	low	low	JJ
cord-010027-r0tl01kq	322	27	grade	grade	NN
cord-010027-r0tl01kq	322	28	NSTs	nst	NNS
cord-010027-r0tl01kq	322	29	(	(	-LRB-
cord-010027-r0tl01kq	322	30	adjusted	adjust	VBN
cord-010027-r0tl01kq	322	31	p	p	NN
cord-010027-r0tl01kq	322	32	value=0.004	value=0.004	NN
cord-010027-r0tl01kq	322	33	)	)	-RRB-
cord-010027-r0tl01kq	322	34	.	.	.
cord-010027-r0tl01kq	323	1	Immunohistochemistry	Immunohistochemistry	NNP
cord-010027-r0tl01kq	323	2	on	on	IN
cord-010027-r0tl01kq	323	3	the	the	DT
cord-010027-r0tl01kq	323	4	Tenovus	Tenovus	NNP
cord-010027-r0tl01kq	323	5	series	series	NN
cord-010027-r0tl01kq	323	6	showed	show	VBD
cord-010027-r0tl01kq	323	7	positive	positive	JJ
cord-010027-r0tl01kq	323	8	nuclear	nuclear	JJ
cord-010027-r0tl01kq	323	9	SOCS2	socs2	NN
cord-010027-r0tl01kq	323	10	expression	expression	NN
cord-010027-r0tl01kq	323	11	to	to	TO
cord-010027-r0tl01kq	323	12	correlate	correlate	VB
cord-010027-r0tl01kq	323	13	with	with	IN
cord-010027-r0tl01kq	323	14	tumours	tumour	NNS
cord-010027-r0tl01kq	323	15	of	of	IN
cord-010027-r0tl01kq	323	16	low	low	JJ
cord-010027-r0tl01kq	323	17	grade	grade	NN
cord-010027-r0tl01kq	323	18	(	(	-LRB-
cord-010027-r0tl01kq	323	19	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	323	20	)	)	-RRB-
cord-010027-r0tl01kq	323	21	,	,	,
cord-010027-r0tl01kq	323	22	low	low	JJ
cord-010027-r0tl01kq	323	23	proliferation	proliferation	NN
cord-010027-r0tl01kq	323	24	(	(	-LRB-
cord-010027-r0tl01kq	323	25	Ki67	Ki67	NNP
cord-010027-r0tl01kq	323	26	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	323	27	)	)	-RRB-
cord-010027-r0tl01kq	323	28	,	,	,
cord-010027-r0tl01kq	323	29	ER	ER	NNP
cord-010027-r0tl01kq	323	30	/	/	SYM
cord-010027-r0tl01kq	323	31	PR	PR	NNP
cord-010027-r0tl01kq	323	32	positive	positive	JJ
cord-010027-r0tl01kq	323	33	(	(	-LRB-
cord-010027-r0tl01kq	323	34	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	323	35	)	)	-RRB-
cord-010027-r0tl01kq	323	36	phenotype	phenotype	NN
cord-010027-r0tl01kq	323	37	and	and	CC
cord-010027-r0tl01kq	323	38	tubular	tubular	JJ
cord-010027-r0tl01kq	323	39	morphology	morphology	NN
cord-010027-r0tl01kq	323	40	(	(	-LRB-
cord-010027-r0tl01kq	323	41	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	323	42	)	)	-RRB-
cord-010027-r0tl01kq	323	43	;	;	:
cord-010027-r0tl01kq	323	44	as	as	RB
cord-010027-r0tl01kq	323	45	well	well	RB
cord-010027-r0tl01kq	323	46	as	as	IN
cord-010027-r0tl01kq	323	47	negative	negative	JJ
cord-010027-r0tl01kq	323	48	HER2	her2	JJ
cord-010027-r0tl01kq	323	49	status	status	NN
cord-010027-r0tl01kq	323	50	(	(	-LRB-
cord-010027-r0tl01kq	323	51	p=0.005	p=0.005	NNP
cord-010027-r0tl01kq	323	52	)	)	-RRB-
cord-010027-r0tl01kq	323	53	and	and	CC
cord-010027-r0tl01kq	323	54	non	non	JJ
cord-010027-r0tl01kq	323	55	-	-	JJ
cord-010027-r0tl01kq	323	56	triple	triple	JJ
cord-010027-r0tl01kq	323	57	negative	negative	JJ
cord-010027-r0tl01kq	323	58	status	status	NN
cord-010027-r0tl01kq	323	59	(	(	-LRB-
cord-010027-r0tl01kq	323	60	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	323	61	)	)	-RRB-
cord-010027-r0tl01kq	323	62	.	.	.
cord-010027-r0tl01kq	324	1	Survival	survival	NN
cord-010027-r0tl01kq	324	2	analysis	analysis	NN
cord-010027-r0tl01kq	324	3	revealed	reveal	VBD
cord-010027-r0tl01kq	324	4	significant	significant	JJ
cord-010027-r0tl01kq	324	5	associations	association	NNS
cord-010027-r0tl01kq	324	6	with	with	IN
cord-010027-r0tl01kq	324	7	long	long	JJ
cord-010027-r0tl01kq	324	8	term	term	NN
cord-010027-r0tl01kq	324	9	breast	breast	NN
cord-010027-r0tl01kq	324	10	cancer	cancer	NN
cord-010027-r0tl01kq	324	11	specific	specific	JJ
cord-010027-r0tl01kq	324	12	survival	survival	NN
cord-010027-r0tl01kq	324	13	(	(	-LRB-
cord-010027-r0tl01kq	324	14	p=0.019	p=0.019	NNP
cord-010027-r0tl01kq	324	15	)	)	-RRB-
cord-010027-r0tl01kq	324	16	.	.	.
cord-010027-r0tl01kq	325	1	Positive	positive	JJ
cord-010027-r0tl01kq	325	2	SOCS2	socs2	NN
cord-010027-r0tl01kq	325	3	correlations	correlation	NNS
cord-010027-r0tl01kq	325	4	were	be	VBD
cord-010027-r0tl01kq	325	5	also	also	RB
cord-010027-r0tl01kq	325	6	observed	observe	VBN
cord-010027-r0tl01kq	325	7	with	with	IN
cord-010027-r0tl01kq	325	8	the	the	DT
cord-010027-r0tl01kq	325	9	expression	expression	NN
cord-010027-r0tl01kq	325	10	of	of	IN
cord-010027-r0tl01kq	325	11	androgen	androgen	NN
cord-010027-r0tl01kq	325	12	receptor	receptor	NN
cord-010027-r0tl01kq	325	13	(	(	-LRB-
cord-010027-r0tl01kq	325	14	AR	AR	NNP
cord-010027-r0tl01kq	325	15	)	)	-RRB-
cord-010027-r0tl01kq	325	16	(	(	-LRB-
cord-010027-r0tl01kq	325	17	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	325	18	)	)	-RRB-
cord-010027-r0tl01kq	325	19	and	and	CC
cord-010027-r0tl01kq	325	20	STAT3	STAT3	NNP
cord-010027-r0tl01kq	325	21	(	(	-LRB-
cord-010027-r0tl01kq	325	22	p=0.001	p=0.001	NNP
cord-010027-r0tl01kq	325	23	)	)	-RRB-
cord-010027-r0tl01kq	325	24	,	,	,
cord-010027-r0tl01kq	325	25	further	further	RB
cord-010027-r0tl01kq	325	26	indicating	indicate	VBG
cord-010027-r0tl01kq	325	27	its	-PRON-	PRP$
cord-010027-r0tl01kq	325	28	role	role	NN
cord-010027-r0tl01kq	325	29	in	in	IN
cord-010027-r0tl01kq	325	30	these	these	DT
cord-010027-r0tl01kq	325	31	two	two	CD
cord-010027-r0tl01kq	325	32	signalling	signal	VBG
cord-010027-r0tl01kq	325	33	pathways	pathway	NNS
cord-010027-r0tl01kq	325	34	.	.	.
cord-010027-r0tl01kq	326	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	326	2	:	:	:
cord-010027-r0tl01kq	327	1	Results	result	NNS
cord-010027-r0tl01kq	327	2	from	from	IN
cord-010027-r0tl01kq	327	3	this	this	DT
cord-010027-r0tl01kq	327	4	study	study	NN
cord-010027-r0tl01kq	327	5	suggest	suggest	VBP
cord-010027-r0tl01kq	327	6	SOCS2	socs2	NN
cord-010027-r0tl01kq	327	7	to	to	TO
cord-010027-r0tl01kq	327	8	be	be	VB
cord-010027-r0tl01kq	327	9	a	a	DT
cord-010027-r0tl01kq	327	10	marker	marker	NN
cord-010027-r0tl01kq	327	11	of	of	IN
cord-010027-r0tl01kq	327	12	favourable	favourable	JJ
cord-010027-r0tl01kq	327	13	prognosis	prognosis	NN
cord-010027-r0tl01kq	327	14	:	:	:
cord-010027-r0tl01kq	327	15	identifying	identify	VBG
cord-010027-r0tl01kq	327	16	low	low	JJ
cord-010027-r0tl01kq	327	17	grade	grade	NN
cord-010027-r0tl01kq	327	18	,	,	,
cord-010027-r0tl01kq	327	19	ER	ER	NNP
cord-010027-r0tl01kq	327	20	positive	positive	JJ
cord-010027-r0tl01kq	327	21	breast	breast	NN
cord-010027-r0tl01kq	327	22	tumours	tumour	NNS
cord-010027-r0tl01kq	327	23	with	with	IN
cord-010027-r0tl01kq	327	24	particular	particular	JJ
cord-010027-r0tl01kq	327	25	correlations	correlation	NNS
cord-010027-r0tl01kq	327	26	to	to	IN
cord-010027-r0tl01kq	327	27	the	the	DT
cord-010027-r0tl01kq	327	28	tubular	tubular	JJ
cord-010027-r0tl01kq	327	29	histological	histological	JJ
cord-010027-r0tl01kq	327	30	tumour	tumour	NN
cord-010027-r0tl01kq	327	31	type	type	NN
cord-010027-r0tl01kq	327	32	.	.	.
cord-010027-r0tl01kq	328	1	Background	background	NN
cord-010027-r0tl01kq	328	2	:	:	:
cord-010027-r0tl01kq	329	1	Ovarian	ovarian	JJ
cord-010027-r0tl01kq	329	2	cancer	cancer	NN
cord-010027-r0tl01kq	329	3	is	be	VBZ
cord-010027-r0tl01kq	329	4	the	the	DT
cord-010027-r0tl01kq	329	5	fifth	fifth	JJ
cord-010027-r0tl01kq	329	6	leading	leading	JJ
cord-010027-r0tl01kq	329	7	cause	cause	NN
cord-010027-r0tl01kq	329	8	of	of	IN
cord-010027-r0tl01kq	329	9	cancer	cancer	NN
cord-010027-r0tl01kq	329	10	in	in	IN
cord-010027-r0tl01kq	329	11	women	woman	NNS
cord-010027-r0tl01kq	329	12	and	and	CC
cord-010027-r0tl01kq	329	13	has	have	VBZ
cord-010027-r0tl01kq	329	14	poor	poor	JJ
cord-010027-r0tl01kq	329	15	long	long	JJ
cord-010027-r0tl01kq	329	16	-	-	HYPH
cord-010027-r0tl01kq	329	17	term	term	NN
cord-010027-r0tl01kq	329	18	survival	survival	NN
cord-010027-r0tl01kq	329	19	,	,	,
cord-010027-r0tl01kq	329	20	in	in	IN
cord-010027-r0tl01kq	329	21	part	part	NN
cord-010027-r0tl01kq	329	22	,	,	,
cord-010027-r0tl01kq	329	23	due	due	IN
cord-010027-r0tl01kq	329	24	to	to	IN
cord-010027-r0tl01kq	329	25	chemoresistance	chemoresistance	NNP
cord-010027-r0tl01kq	329	26	.	.	.
cord-010027-r0tl01kq	330	1	Tumour	tumour	NN
cord-010027-r0tl01kq	330	2	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	330	3	is	be	VBZ
cord-010027-r0tl01kq	330	4	associated	associate	VBN
cord-010027-r0tl01kq	330	5	with	with	IN
cord-010027-r0tl01kq	330	6	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	330	7	in	in	IN
cord-010027-r0tl01kq	330	8	ovarian	ovarian	JJ
cord-010027-r0tl01kq	330	9	cancer	cancer	NN
cord-010027-r0tl01kq	330	10	.	.	.
cord-010027-r0tl01kq	331	1	However	however	RB
cord-010027-r0tl01kq	331	2	,	,	,
cord-010027-r0tl01kq	331	3	relatively	relatively	RB
cord-010027-r0tl01kq	331	4	little	little	JJ
cord-010027-r0tl01kq	331	5	is	be	VBZ
cord-010027-r0tl01kq	331	6	known	know	VBN
cord-010027-r0tl01kq	331	7	about	about	IN
cord-010027-r0tl01kq	331	8	the	the	DT
cord-010027-r0tl01kq	331	9	genes	gene	NNS
cord-010027-r0tl01kq	331	10	activated	activate	VBN
cord-010027-r0tl01kq	331	11	in	in	IN
cord-010027-r0tl01kq	331	12	ovarian	ovarian	JJ
cord-010027-r0tl01kq	331	13	cancer	cancer	NN
cord-010027-r0tl01kq	331	14	which	which	WDT
cord-010027-r0tl01kq	331	15	cause	cause	VBP
cord-010027-r0tl01kq	331	16	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	331	17	due	due	IN
cord-010027-r0tl01kq	331	18	to	to	IN
cord-010027-r0tl01kq	331	19	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	331	20	.	.	.
cord-010027-r0tl01kq	332	1	This	this	DT
cord-010027-r0tl01kq	332	2	study	study	NN
cord-010027-r0tl01kq	332	3	aimed	aim	VBD
cord-010027-r0tl01kq	332	4	to	to	TO
cord-010027-r0tl01kq	332	5	firstly	firstly	RB
cord-010027-r0tl01kq	332	6	identify	identify	VB
cord-010027-r0tl01kq	332	7	genes	gene	NNS
cord-010027-r0tl01kq	332	8	whose	whose	WP$
cord-010027-r0tl01kq	332	9	expression	expression	NN
cord-010027-r0tl01kq	332	10	is	be	VBZ
cord-010027-r0tl01kq	332	11	associated	associate	VBN
cord-010027-r0tl01kq	332	12	with	with	IN
cord-010027-r0tl01kq	332	13	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	332	14	-	-	HYPH
cord-010027-r0tl01kq	332	15	induced	induce	VBN
cord-010027-r0tl01kq	332	16	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	332	17	,	,	,
cord-010027-r0tl01kq	332	18	and	and	CC
cord-010027-r0tl01kq	332	19	secondly	secondly	RB
cord-010027-r0tl01kq	332	20	select	select	VB
cord-010027-r0tl01kq	332	21	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	332	22	-	-	HYPH
cord-010027-r0tl01kq	332	23	associated	associate	VBN
cord-010027-r0tl01kq	332	24	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	332	25	and	and	CC
cord-010027-r0tl01kq	332	26	evaluate	evaluate	VB
cord-010027-r0tl01kq	332	27	their	-PRON-	PRP$
cord-010027-r0tl01kq	332	28	expression	expression	NN
cord-010027-r0tl01kq	332	29	in	in	IN
cord-010027-r0tl01kq	332	30	ovarian	ovarian	JJ
cord-010027-r0tl01kq	332	31	tumours	tumour	NNS
cord-010027-r0tl01kq	332	32	.	.	.
cord-010027-r0tl01kq	333	1	Methods	method	NNS
cord-010027-r0tl01kq	333	2	:	:	:
cord-010027-r0tl01kq	334	1	Cisplatin	cisplatin	NN
cord-010027-r0tl01kq	334	2	-	-	HYPH
cord-010027-r0tl01kq	334	3	sensitive	sensitive	JJ
cord-010027-r0tl01kq	334	4	(	(	-LRB-
cord-010027-r0tl01kq	334	5	A2780	A2780	NNP
cord-010027-r0tl01kq	334	6	)	)	-RRB-
cord-010027-r0tl01kq	334	7	and	and	CC
cord-010027-r0tl01kq	334	8	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	334	9	-	-	HYPH
cord-010027-r0tl01kq	334	10	resistant	resistant	JJ
cord-010027-r0tl01kq	335	1	(	(	-LRB-
cord-010027-r0tl01kq	335	2	A2780cis	A2780cis	NNP
cord-010027-r0tl01kq	335	3	)	)	-RRB-
cord-010027-r0tl01kq	335	4	ovarian	ovarian	JJ
cord-010027-r0tl01kq	335	5	cancer	cancer	NN
cord-010027-r0tl01kq	335	6	cell	cell	NN
cord-010027-r0tl01kq	335	7	lines	line	NNS
cord-010027-r0tl01kq	335	8	were	be	VBD
cord-010027-r0tl01kq	335	9	exposed	expose	VBN
cord-010027-r0tl01kq	335	10	to	to	IN
cord-010027-r0tl01kq	335	11	combinations	combination	NNS
cord-010027-r0tl01kq	335	12	of	of	IN
cord-010027-r0tl01kq	335	13	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	335	14	and/or	and/or	CC
cord-010027-r0tl01kq	336	1	cisplatin	cisplatin	RB
cord-010027-r0tl01kq	336	2	as	as	IN
cord-010027-r0tl01kq	336	3	part	part	NN
cord-010027-r0tl01kq	336	4	of	of	IN
cord-010027-r0tl01kq	336	5	a	a	DT
cord-010027-r0tl01kq	336	6	matrix	matrix	NN
cord-010027-r0tl01kq	336	7	designed	design	VBN
cord-010027-r0tl01kq	336	8	to	to	TO
cord-010027-r0tl01kq	336	9	reflect	reflect	VB
cord-010027-r0tl01kq	336	10	clinically	clinically	RB
cord-010027-r0tl01kq	336	11	relevant	relevant	JJ
cord-010027-r0tl01kq	336	12	scenarios	scenario	NNS
cord-010027-r0tl01kq	336	13	.	.	.
cord-010027-r0tl01kq	337	1	RNA	RNA	NNP
cord-010027-r0tl01kq	337	2	was	be	VBD
cord-010027-r0tl01kq	337	3	extracted	extract	VBN
cord-010027-r0tl01kq	337	4	and	and	CC
cord-010027-r0tl01kq	337	5	interrogated	interrogate	VBN
cord-010027-r0tl01kq	337	6	on	on	IN
cord-010027-r0tl01kq	337	7	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	337	8	Human	Human	NNP
cord-010027-r0tl01kq	337	9	Gene	Gene	NNP
cord-010027-r0tl01kq	337	10	arrays	array	NNS
cord-010027-r0tl01kq	337	11	.	.	.
cord-010027-r0tl01kq	338	1	Differential	differential	JJ
cord-010027-r0tl01kq	338	2	gene	gene	NN
cord-010027-r0tl01kq	338	3	expression	expression	NN
cord-010027-r0tl01kq	338	4	was	be	VBD
cord-010027-r0tl01kq	338	5	analysed	analyse	VBN
cord-010027-r0tl01kq	338	6	for	for	IN
cord-010027-r0tl01kq	338	7	cells	cell	NNS
cord-010027-r0tl01kq	338	8	exposed	expose	VBN
cord-010027-r0tl01kq	338	9	to	to	IN
cord-010027-r0tl01kq	338	10	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	338	11	and/or	and/or	CC
cord-010027-r0tl01kq	338	12	treated	treat	VBN
cord-010027-r0tl01kq	338	13	with	with	IN
cord-010027-r0tl01kq	338	14	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	338	15	.	.	.
cord-010027-r0tl01kq	339	1	Potential	potential	JJ
cord-010027-r0tl01kq	339	2	markers	marker	NNS
cord-010027-r0tl01kq	339	3	of	of	IN
cord-010027-r0tl01kq	339	4	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	339	5	were	be	VBD
cord-010027-r0tl01kq	339	6	selected	select	VBN
cord-010027-r0tl01kq	339	7	for	for	IN
cord-010027-r0tl01kq	339	8	evaluation	evaluation	NN
cord-010027-r0tl01kq	339	9	in	in	IN
cord-010027-r0tl01kq	339	10	a	a	DT
cord-010027-r0tl01kq	339	11	cohort	cohort	NN
cord-010027-r0tl01kq	339	12	of	of	IN
cord-010027-r0tl01kq	339	13	ovarian	ovarian	JJ
cord-010027-r0tl01kq	339	14	tumour	tumour	NN
cord-010027-r0tl01kq	339	15	samples	sample	NNS
cord-010027-r0tl01kq	339	16	by	by	IN
cord-010027-r0tl01kq	339	17	RT	RT	NNP
cord-010027-r0tl01kq	339	18	-	-	HYPH
cord-010027-r0tl01kq	339	19	PCR	PCR	NNP
cord-010027-r0tl01kq	339	20	.	.	.
cord-010027-r0tl01kq	340	1	Results	result	NNS
cord-010027-r0tl01kq	340	2	:	:	:
cord-010027-r0tl01kq	341	1	A	a	DT
cord-010027-r0tl01kq	341	2	wide	wide	JJ
cord-010027-r0tl01kq	341	3	range	range	NN
cord-010027-r0tl01kq	341	4	of	of	IN
cord-010027-r0tl01kq	341	5	genes	gene	NNS
cord-010027-r0tl01kq	341	6	associated	associate	VBN
cord-010027-r0tl01kq	341	7	with	with	IN
cord-010027-r0tl01kq	341	8	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	341	9	were	be	VBD
cord-010027-r0tl01kq	341	10	differentially	differentially	RB
cord-010027-r0tl01kq	341	11	expressed	express	VBN
cord-010027-r0tl01kq	341	12	in	in	IN
cord-010027-r0tl01kq	341	13	cells	cell	NNS
cord-010027-r0tl01kq	341	14	exposed	expose	VBN
cord-010027-r0tl01kq	341	15	to	to	IN
cord-010027-r0tl01kq	341	16	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	341	17	and/or	and/or	CC
cord-010027-r0tl01kq	341	18	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	341	19	.	.	.
cord-010027-r0tl01kq	342	1	Selected	select	VBN
cord-010027-r0tl01kq	342	2	genes	gene	NNS
cord-010027-r0tl01kq	342	3	[	[	-LRB-
cord-010027-r0tl01kq	342	4	ANGPTL4	ANGPTL4	NNP
cord-010027-r0tl01kq	342	5	,	,	,
cord-010027-r0tl01kq	342	6	HER3	HER3	NNP
cord-010027-r0tl01kq	342	7	and	and	CC
cord-010027-r0tl01kq	342	8	HIF-1α	HIF-1α	NNP
cord-010027-r0tl01kq	342	9	]	]	-RRB-
cord-010027-r0tl01kq	342	10	were	be	VBD
cord-010027-r0tl01kq	342	11	chosen	choose	VBN
cord-010027-r0tl01kq	342	12	for	for	IN
cord-010027-r0tl01kq	342	13	further	further	JJ
cord-010027-r0tl01kq	342	14	validation	validation	NN
cord-010027-r0tl01kq	342	15	in	in	IN
cord-010027-r0tl01kq	342	16	a	a	DT
cord-010027-r0tl01kq	342	17	cohort	cohort	NN
cord-010027-r0tl01kq	342	18	of	of	IN
cord-010027-r0tl01kq	342	19	ovarian	ovarian	JJ
cord-010027-r0tl01kq	342	20	tumour	tumour	NN
cord-010027-r0tl01kq	342	21	samples	sample	NNS
cord-010027-r0tl01kq	342	22	,	,	,
cord-010027-r0tl01kq	342	23	n=35	n=35	PRP
cord-010027-r0tl01kq	342	24	.	.	.
cord-010027-r0tl01kq	343	1	High	high	JJ
cord-010027-r0tl01kq	343	2	expression	expression	NN
cord-010027-r0tl01kq	343	3	of	of	IN
cord-010027-r0tl01kq	343	4	ANGPTL4	ANGPTL4	NNP
cord-010027-r0tl01kq	343	5	trended	trend	VBN
cord-010027-r0tl01kq	343	6	towards	towards	IN
cord-010027-r0tl01kq	343	7	reduced	reduce	VBN
cord-010027-r0tl01kq	343	8	progression	progression	NN
cord-010027-r0tl01kq	343	9	-	-	HYPH
cord-010027-r0tl01kq	343	10	free	free	JJ
cord-010027-r0tl01kq	343	11	and	and	CC
cord-010027-r0tl01kq	343	12	overall	overall	JJ
cord-010027-r0tl01kq	343	13	survival	survival	NN
cord-010027-r0tl01kq	343	14	.	.	.
cord-010027-r0tl01kq	344	1	High	high	JJ
cord-010027-r0tl01kq	344	2	expression	expression	NN
cord-010027-r0tl01kq	344	3	of	of	IN
cord-010027-r0tl01kq	344	4	HER3	HER3	NNP
cord-010027-r0tl01kq	344	5	trended	trend	VBD
cord-010027-r0tl01kq	344	6	to	to	IN
cord-010027-r0tl01kq	344	7	increased	increase	VBN
cord-010027-r0tl01kq	344	8	progression	progression	NN
cord-010027-r0tl01kq	344	9	-	-	HYPH
cord-010027-r0tl01kq	344	10	free	free	JJ
cord-010027-r0tl01kq	344	11	but	but	CC
cord-010027-r0tl01kq	344	12	reduced	reduced	JJ
cord-010027-r0tl01kq	344	13	overall	overall	JJ
cord-010027-r0tl01kq	344	14	survival	survival	NN
cord-010027-r0tl01kq	344	15	,	,	,
cord-010027-r0tl01kq	344	16	while	while	IN
cord-010027-r0tl01kq	344	17	high	high	JJ
cord-010027-r0tl01kq	344	18	expression	expression	NN
cord-010027-r0tl01kq	344	19	of	of	IN
cord-010027-r0tl01kq	344	20	HIF-1α	HIF-1α	NNP
cord-010027-r0tl01kq	344	21	trended	trend	VBD
cord-010027-r0tl01kq	344	22	towards	towards	IN
cord-010027-r0tl01kq	344	23	reduced	reduce	VBN
cord-010027-r0tl01kq	344	24	progression	progression	NN
cord-010027-r0tl01kq	344	25	-	-	HYPH
cord-010027-r0tl01kq	344	26	free	free	JJ
cord-010027-r0tl01kq	344	27	and	and	CC
cord-010027-r0tl01kq	344	28	increased	increase	VBN
cord-010027-r0tl01kq	344	29	overall	overall	JJ
cord-010027-r0tl01kq	344	30	survival	survival	NN
cord-010027-r0tl01kq	344	31	.	.	.
cord-010027-r0tl01kq	345	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	345	2	:	:	:
cord-010027-r0tl01kq	346	1	This	this	DT
cord-010027-r0tl01kq	346	2	study	study	NN
cord-010027-r0tl01kq	346	3	has	have	VBZ
cord-010027-r0tl01kq	346	4	further	further	RB
cord-010027-r0tl01kq	346	5	characterized	characterize	VBN
cord-010027-r0tl01kq	346	6	the	the	DT
cord-010027-r0tl01kq	346	7	relationship	relationship	NN
cord-010027-r0tl01kq	346	8	between	between	IN
cord-010027-r0tl01kq	346	9	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	346	10	and	and	CC
cord-010027-r0tl01kq	346	11	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	346	12	in	in	IN
cord-010027-r0tl01kq	346	13	an	an	DT
cord-010027-r0tl01kq	346	14	ovarian	ovarian	JJ
cord-010027-r0tl01kq	346	15	cancer	cancer	NN
cord-010027-r0tl01kq	346	16	model	model	NN
cord-010027-r0tl01kq	346	17	.	.	.
cord-010027-r0tl01kq	347	1	We	-PRON-	PRP
cord-010027-r0tl01kq	347	2	have	have	VBP
cord-010027-r0tl01kq	347	3	also	also	RB
cord-010027-r0tl01kq	347	4	identified	identify	VBN
cord-010027-r0tl01kq	347	5	many	many	JJ
cord-010027-r0tl01kq	347	6	potential	potential	JJ
cord-010027-r0tl01kq	347	7	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	347	8	of	of	IN
cord-010027-r0tl01kq	347	9	hypoxia	hypoxia	NN
cord-010027-r0tl01kq	347	10	and	and	CC
cord-010027-r0tl01kq	347	11	platinum	platinum	NN
cord-010027-r0tl01kq	347	12	resistance	resistance	NN
cord-010027-r0tl01kq	347	13	and	and	CC
cord-010027-r0tl01kq	347	14	provide	provide	VB
cord-010027-r0tl01kq	347	15	initial	initial	JJ
cord-010027-r0tl01kq	347	16	validation	validation	NN
cord-010027-r0tl01kq	347	17	of	of	IN
cord-010027-r0tl01kq	347	18	a	a	DT
cord-010027-r0tl01kq	347	19	subset	subset	NN
cord-010027-r0tl01kq	347	20	of	of	IN
cord-010027-r0tl01kq	347	21	these	these	DT
cord-010027-r0tl01kq	347	22	markers	marker	NNS
cord-010027-r0tl01kq	347	23	in	in	IN
cord-010027-r0tl01kq	347	24	ovarian	ovarian	JJ
cord-010027-r0tl01kq	347	25	cancer	cancer	NN
cord-010027-r0tl01kq	347	26	tissues	tissue	NNS
cord-010027-r0tl01kq	347	27	.	.	.
cord-010027-r0tl01kq	348	1	Methods	method	NNS
cord-010027-r0tl01kq	348	2	:	:	:
cord-010027-r0tl01kq	348	3	Analysis	Analysis	NNP
cord-010027-r0tl01kq	348	4	of	of	IN
cord-010027-r0tl01kq	348	5	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	348	6	™	™	HYPH
cord-010027-r0tl01kq	348	7	Human	Human	NNP
cord-010027-r0tl01kq	348	8	Exon	Exon	NNP
cord-010027-r0tl01kq	348	9	1.0ST	1.0st	CD
cord-010027-r0tl01kq	348	10	microarray	microarray	NN
cord-010027-r0tl01kq	348	11	data	datum	NNS
cord-010027-r0tl01kq	348	12	revealed	reveal	VBD
cord-010027-r0tl01kq	348	13	differentially	differentially	RB
cord-010027-r0tl01kq	348	14	expressed	express	VBN
cord-010027-r0tl01kq	348	15	genes	gene	NNS
cord-010027-r0tl01kq	348	16	(	(	-LRB-
cord-010027-r0tl01kq	348	17	DEGs	DEGs	NNP
cord-010027-r0tl01kq	348	18	)	)	-RRB-
cord-010027-r0tl01kq	348	19	between	between	IN
cord-010027-r0tl01kq	348	20	a	a	DT
cord-010027-r0tl01kq	348	21	BC	BC	NNP
cord-010027-r0tl01kq	348	22	group	group	NN
cord-010027-r0tl01kq	348	23	and	and	CC
cord-010027-r0tl01kq	348	24	a	a	DT
cord-010027-r0tl01kq	348	25	control	control	NN
cord-010027-r0tl01kq	348	26	non	non	JJ
cord-010027-r0tl01kq	348	27	-	-	JJ
cord-010027-r0tl01kq	348	28	BC	BC	NNP
cord-010027-r0tl01kq	348	29	group	group	NN
cord-010027-r0tl01kq	348	30	.	.	.
cord-010027-r0tl01kq	349	1	Ingenuity	Ingenuity	NNP
cord-010027-r0tl01kq	349	2	Pathway	Pathway	NNP
cord-010027-r0tl01kq	349	3	Analysis	Analysis	NNP
cord-010027-r0tl01kq	349	4	(	(	-LRB-
cord-010027-r0tl01kq	349	5	IPA	IPA	NNP
cord-010027-r0tl01kq	349	6	;	;	,
cord-010027-r0tl01kq	349	7	bioinformatics	bioinformatics	NN
cord-010027-r0tl01kq	349	8	software	software	NN
cord-010027-r0tl01kq	349	9	)	)	-RRB-
cord-010027-r0tl01kq	349	10	was	be	VBD
cord-010027-r0tl01kq	349	11	used	use	VBN
cord-010027-r0tl01kq	349	12	to	to	TO
cord-010027-r0tl01kq	349	13	identify	identify	VB
cord-010027-r0tl01kq	349	14	networks	network	NNS
cord-010027-r0tl01kq	349	15	of	of	IN
cord-010027-r0tl01kq	349	16	the	the	DT
cord-010027-r0tl01kq	349	17	DEGs	deg	NNS
cord-010027-r0tl01kq	349	18	.	.	.
cord-010027-r0tl01kq	350	1	The	the	DT
cord-010027-r0tl01kq	350	2	expression	expression	NN
cord-010027-r0tl01kq	350	3	of	of	IN
cord-010027-r0tl01kq	350	4	a	a	DT
cord-010027-r0tl01kq	350	5	micro	micro	JJ
cord-010027-r0tl01kq	350	6	-	-	NN
cord-010027-r0tl01kq	350	7	network	network	NN
cord-010027-r0tl01kq	350	8	was	be	VBD
cord-010027-r0tl01kq	350	9	validated	validate	VBN
cord-010027-r0tl01kq	350	10	using	use	VBG
cord-010027-r0tl01kq	350	11	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	350	12	.	.	.
cord-010027-r0tl01kq	351	1	Double	double	JJ
cord-010027-r0tl01kq	351	2	immunofluorescence	immunofluorescence	NN
cord-010027-r0tl01kq	351	3	was	be	VBD
cord-010027-r0tl01kq	351	4	undertaken	undertake	VBN
cord-010027-r0tl01kq	351	5	to	to	TO
cord-010027-r0tl01kq	351	6	identify	identify	VB
cord-010027-r0tl01kq	351	7	the	the	DT
cord-010027-r0tl01kq	351	8	lineage	lineage	NN
cord-010027-r0tl01kq	351	9	of	of	IN
cord-010027-r0tl01kq	351	10	cells	cell	NNS
cord-010027-r0tl01kq	351	11	expressing	express	VBG
cord-010027-r0tl01kq	351	12	components	component	NNS
cord-010027-r0tl01kq	351	13	of	of	IN
cord-010027-r0tl01kq	351	14	the	the	DT
cord-010027-r0tl01kq	351	15	network	network	NN
cord-010027-r0tl01kq	351	16	.	.	.
cord-010027-r0tl01kq	352	1	Results	result	NNS
cord-010027-r0tl01kq	352	2	:	:	:
cord-010027-r0tl01kq	353	1	We	-PRON-	PRP
cord-010027-r0tl01kq	353	2	identified	identify	VBD
cord-010027-r0tl01kq	353	3	a	a	DT
cord-010027-r0tl01kq	353	4	network	network	NN
cord-010027-r0tl01kq	353	5	of	of	IN
cord-010027-r0tl01kq	353	6	interacting	interact	VBG
cord-010027-r0tl01kq	353	7	genes	gene	NNS
cord-010027-r0tl01kq	353	8	that	that	WDT
cord-010027-r0tl01kq	353	9	were	be	VBD
cord-010027-r0tl01kq	353	10	upregulated	upregulate	VBN
cord-010027-r0tl01kq	353	11	in	in	IN
cord-010027-r0tl01kq	353	12	FCDIIb	FCDIIb	NNS
cord-010027-r0tl01kq	353	13	compared	compare	VBN
cord-010027-r0tl01kq	353	14	to	to	IN
cord-010027-r0tl01kq	353	15	normally	normally	RB
cord-010027-r0tl01kq	353	16	formed	form	VBN
cord-010027-r0tl01kq	353	17	cortex	cortex	NN
cord-010027-r0tl01kq	353	18	or	or	CC
cord-010027-r0tl01kq	353	19	FCD	FCD	NNP
cord-010027-r0tl01kq	353	20	without	without	IN
cord-010027-r0tl01kq	353	21	balloon	balloon	NN
cord-010027-r0tl01kq	353	22	cells	cell	NNS
cord-010027-r0tl01kq	353	23	(	(	-LRB-
cord-010027-r0tl01kq	353	24	FCDIIa	FCDIIa	NNS
cord-010027-r0tl01kq	353	25	)	)	-RRB-
cord-010027-r0tl01kq	353	26	.	.	.
cord-010027-r0tl01kq	354	1	Some	some	DT
cord-010027-r0tl01kq	354	2	components	component	NNS
cord-010027-r0tl01kq	354	3	of	of	IN
cord-010027-r0tl01kq	354	4	this	this	DT
cord-010027-r0tl01kq	354	5	network	network	NN
cord-010027-r0tl01kq	354	6	were	be	VBD
cord-010027-r0tl01kq	354	7	expressed	express	VBN
cord-010027-r0tl01kq	354	8	in	in	IN
cord-010027-r0tl01kq	354	9	BCs	BCs	NNP
cord-010027-r0tl01kq	354	10	but	but	CC
cord-010027-r0tl01kq	354	11	others	other	NNS
cord-010027-r0tl01kq	354	12	were	be	VBD
cord-010027-r0tl01kq	354	13	expressed	express	VBN
cord-010027-r0tl01kq	354	14	in	in	IN
cord-010027-r0tl01kq	354	15	novel	novel	JJ
cord-010027-r0tl01kq	354	16	cell	cell	NN
cord-010027-r0tl01kq	354	17	populations	population	NNS
cord-010027-r0tl01kq	354	18	.	.	.
cord-010027-r0tl01kq	355	1	Double	double	JJ
cord-010027-r0tl01kq	355	2	immunofluorescence	immunofluorescence	NN
cord-010027-r0tl01kq	355	3	identified	identify	VBD
cord-010027-r0tl01kq	355	4	a	a	DT
cord-010027-r0tl01kq	355	5	cell	cell	NN
cord-010027-r0tl01kq	355	6	with	with	IN
cord-010027-r0tl01kq	355	7	the	the	DT
cord-010027-r0tl01kq	355	8	phenotype	phenotype	NN
cord-010027-r0tl01kq	355	9	of	of	IN
cord-010027-r0tl01kq	355	10	a	a	DT
cord-010027-r0tl01kq	355	11	glial	glial	JJ
cord-010027-r0tl01kq	355	12	progenitor	progenitor	NN
cord-010027-r0tl01kq	355	13	that	that	WDT
cord-010027-r0tl01kq	355	14	was	be	VBD
cord-010027-r0tl01kq	355	15	only	only	RB
cord-010027-r0tl01kq	355	16	present	present	JJ
cord-010027-r0tl01kq	355	17	in	in	IN
cord-010027-r0tl01kq	355	18	FCDIIb	FCDIIb	NNS
cord-010027-r0tl01kq	355	19	but	but	CC
cord-010027-r0tl01kq	355	20	not	not	RB
cord-010027-r0tl01kq	355	21	in	in	IN
cord-010027-r0tl01kq	355	22	normally	normally	RB
cord-010027-r0tl01kq	355	23	formed	form	VBN
cord-010027-r0tl01kq	355	24	cortex	cortex	NN
cord-010027-r0tl01kq	355	25	.	.	.
cord-010027-r0tl01kq	356	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	356	2	:	:	:
cord-010027-r0tl01kq	357	1	We	-PRON-	PRP
cord-010027-r0tl01kq	357	2	have	have	VBP
cord-010027-r0tl01kq	357	3	identified	identify	VBN
cord-010027-r0tl01kq	357	4	a	a	DT
cord-010027-r0tl01kq	357	5	novel	novel	JJ
cord-010027-r0tl01kq	357	6	population	population	NN
cord-010027-r0tl01kq	357	7	of	of	IN
cord-010027-r0tl01kq	357	8	glial	glial	JJ
cord-010027-r0tl01kq	357	9	progenitors	progenitor	NNS
cord-010027-r0tl01kq	357	10	found	find	VBN
cord-010027-r0tl01kq	357	11	frequently	frequently	RB
cord-010027-r0tl01kq	357	12	adjacent	adjacent	JJ
cord-010027-r0tl01kq	357	13	to	to	IN
cord-010027-r0tl01kq	357	14	BCs	BCs	NNP
cord-010027-r0tl01kq	357	15	in	in	IN
cord-010027-r0tl01kq	357	16	FCDIIb	FCDIIb	NNP
cord-010027-r0tl01kq	357	17	.	.	.
cord-010027-r0tl01kq	358	1	Paracrine	Paracrine	NNP
cord-010027-r0tl01kq	358	2	signaling	signal	VBG
cord-010027-r0tl01kq	358	3	between	between	IN
cord-010027-r0tl01kq	358	4	BCs	BCs	NNP
cord-010027-r0tl01kq	358	5	and	and	CC
cord-010027-r0tl01kq	358	6	the	the	DT
cord-010027-r0tl01kq	358	7	novel	novel	JJ
cord-010027-r0tl01kq	358	8	CHI3L1	chi3l1	CC
cord-010027-r0tl01kq	358	9	positive	positive	JJ
cord-010027-r0tl01kq	358	10	cells	cell	NNS
cord-010027-r0tl01kq	358	11	is	be	VBZ
cord-010027-r0tl01kq	358	12	likely	likely	JJ
cord-010027-r0tl01kq	358	13	to	to	TO
cord-010027-r0tl01kq	358	14	be	be	VB
cord-010027-r0tl01kq	358	15	involved	involve	VBN
cord-010027-r0tl01kq	358	16	in	in	IN
cord-010027-r0tl01kq	358	17	the	the	DT
cord-010027-r0tl01kq	358	18	pathogenesis	pathogenesis	NN
cord-010027-r0tl01kq	358	19	in	in	IN
cord-010027-r0tl01kq	358	20	FCDIIb	FCDIIb	NNS
cord-010027-r0tl01kq	358	21	.	.	.
cord-010027-r0tl01kq	359	1	Further	further	JJ
cord-010027-r0tl01kq	359	2	investigations	investigation	NNS
cord-010027-r0tl01kq	359	3	into	into	IN
cord-010027-r0tl01kq	359	4	the	the	DT
cord-010027-r0tl01kq	359	5	role	role	NN
cord-010027-r0tl01kq	359	6	of	of	IN
cord-010027-r0tl01kq	359	7	these	these	DT
cord-010027-r0tl01kq	359	8	cells	cell	NNS
cord-010027-r0tl01kq	359	9	would	would	MD
cord-010027-r0tl01kq	359	10	give	give	VB
cord-010027-r0tl01kq	359	11	us	-PRON-	PRP
cord-010027-r0tl01kq	359	12	a	a	DT
cord-010027-r0tl01kq	359	13	better	well	JJR
cord-010027-r0tl01kq	359	14	understanding	understanding	NN
cord-010027-r0tl01kq	359	15	of	of	IN
cord-010027-r0tl01kq	359	16	the	the	DT
cord-010027-r0tl01kq	359	17	molecular	molecular	JJ
cord-010027-r0tl01kq	359	18	abnormalities	abnormality	NNS
cord-010027-r0tl01kq	359	19	underlying	underlie	VBG
cord-010027-r0tl01kq	359	20	FCD	FCD	NNP
cord-010027-r0tl01kq	359	21	and	and	CC
cord-010027-r0tl01kq	359	22	possibly	possibly	RB
cord-010027-r0tl01kq	359	23	provide	provide	VB
cord-010027-r0tl01kq	359	24	novel	novel	JJ
cord-010027-r0tl01kq	359	25	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	359	26	targets	target	NNS
cord-010027-r0tl01kq	359	27	.	.	.
cord-010027-r0tl01kq	360	1	Excellent	excellent	JJ
cord-010027-r0tl01kq	360	2	anatomical	anatomical	JJ
cord-010027-r0tl01kq	360	3	knowledge	knowledge	NN
cord-010027-r0tl01kq	360	4	of	of	IN
cord-010027-r0tl01kq	360	5	the	the	DT
cord-010027-r0tl01kq	360	6	anal	anal	JJ
cord-010027-r0tl01kq	360	7	sphincter	sphincter	NN
cord-010027-r0tl01kq	360	8	complex	complex	NN
cord-010027-r0tl01kq	360	9	(	(	-LRB-
cord-010027-r0tl01kq	360	10	ASC	ASC	NNP
cord-010027-r0tl01kq	360	11	)	)	-RRB-
cord-010027-r0tl01kq	360	12	is	be	VBZ
cord-010027-r0tl01kq	360	13	essential	essential	JJ
cord-010027-r0tl01kq	360	14	for	for	IN
cord-010027-r0tl01kq	360	15	the	the	DT
cord-010027-r0tl01kq	360	16	treatment	treatment	NN
cord-010027-r0tl01kq	360	17	and	and	CC
cord-010027-r0tl01kq	360	18	understanding	understanding	NN
cord-010027-r0tl01kq	360	19	of	of	IN
cord-010027-r0tl01kq	360	20	low	low	JJ
cord-010027-r0tl01kq	360	21	rectal	rectal	JJ
cord-010027-r0tl01kq	360	22	and	and	CC
cord-010027-r0tl01kq	360	23	anal	anal	JJ
cord-010027-r0tl01kq	360	24	pathology	pathology	NN
cord-010027-r0tl01kq	360	25	.	.	.
cord-010027-r0tl01kq	361	1	Some	some	DT
cord-010027-r0tl01kq	361	2	of	of	IN
cord-010027-r0tl01kq	361	3	the	the	DT
cord-010027-r0tl01kq	361	4	current	current	JJ
cord-010027-r0tl01kq	361	5	descriptions	description	NNS
cord-010027-r0tl01kq	361	6	of	of	IN
cord-010027-r0tl01kq	361	7	the	the	DT
cord-010027-r0tl01kq	361	8	ASC	ASC	NNP
cord-010027-r0tl01kq	361	9	are	be	VBP
cord-010027-r0tl01kq	361	10	contradictory	contradictory	JJ
cord-010027-r0tl01kq	361	11	.	.	.
cord-010027-r0tl01kq	362	1	In	in	IN
cord-010027-r0tl01kq	362	2	this	this	DT
cord-010027-r0tl01kq	362	3	study	study	NN
cord-010027-r0tl01kq	362	4	,	,	,
cord-010027-r0tl01kq	362	5	the	the	DT
cord-010027-r0tl01kq	362	6	three	three	CD
cord-010027-r0tl01kq	362	7	-	-	HYPH
cord-010027-r0tl01kq	362	8	dimensional	dimensional	JJ
cord-010027-r0tl01kq	362	9	(	(	-LRB-
cord-010027-r0tl01kq	362	10	3D	3D	NNP
cord-010027-r0tl01kq	362	11	)	)	-RRB-
cord-010027-r0tl01kq	362	12	anatomy	anatomy	NN
cord-010027-r0tl01kq	362	13	of	of	IN
cord-010027-r0tl01kq	362	14	the	the	DT
cord-010027-r0tl01kq	362	15	ASC	ASC	NNP
cord-010027-r0tl01kq	362	16	is	be	VBZ
cord-010027-r0tl01kq	362	17	described	describe	VBN
cord-010027-r0tl01kq	362	18	with	with	IN
cord-010027-r0tl01kq	362	19	relevance	relevance	NN
cord-010027-r0tl01kq	362	20	to	to	IN
cord-010027-r0tl01kq	362	21	low	low	JJ
cord-010027-r0tl01kq	362	22	rectal	rectal	NN
cord-010027-r0tl01kq	362	23	and	and	CC
cord-010027-r0tl01kq	362	24	anal	anal	JJ
cord-010027-r0tl01kq	362	25	surgical	surgical	JJ
cord-010027-r0tl01kq	362	26	pathology	pathology	NN
cord-010027-r0tl01kq	362	27	.	.	.
cord-010027-r0tl01kq	363	1	Six	six	CD
cord-010027-r0tl01kq	363	2	human	human	JJ
cord-010027-r0tl01kq	363	3	adult	adult	NN
cord-010027-r0tl01kq	363	4	cadaveric	cadaveric	JJ
cord-010027-r0tl01kq	363	5	specimens	specimen	NNS
cord-010027-r0tl01kq	363	6	(	(	-LRB-
cord-010027-r0tl01kq	363	7	three	three	CD
cord-010027-r0tl01kq	363	8	males	male	NNS
cord-010027-r0tl01kq	363	9	,	,	,
cord-010027-r0tl01kq	363	10	three	three	CD
cord-010027-r0tl01kq	363	11	females	female	NNS
cord-010027-r0tl01kq	363	12	)	)	-RRB-
cord-010027-r0tl01kq	363	13	were	be	VBD
cord-010027-r0tl01kq	363	14	obtained	obtain	VBN
cord-010027-r0tl01kq	363	15	from	from	IN
cord-010027-r0tl01kq	363	16	the	the	DT
cord-010027-r0tl01kq	363	17	Leeds	Leeds	NNP
cord-010027-r0tl01kq	363	18	GIFT	GIFT	NNP
cord-010027-r0tl01kq	363	19	Research	Research	NNP
cord-010027-r0tl01kq	363	20	Tissue	Tissue	NNP
cord-010027-r0tl01kq	363	21	Programme	Programme	NNP
cord-010027-r0tl01kq	363	22	.	.	.
cord-010027-r0tl01kq	364	1	Paraffin	paraffin	NN
cord-010027-r0tl01kq	364	2	embedded	embed	VBN
cord-010027-r0tl01kq	364	3	mega	mega	NNS
cord-010027-r0tl01kq	364	4	-	-	NNS
cord-010027-r0tl01kq	364	5	blocks	block	NNS
cord-010027-r0tl01kq	364	6	containing	contain	VBG
cord-010027-r0tl01kq	364	7	the	the	DT
cord-010027-r0tl01kq	364	8	ASC	ASC	NNP
cord-010027-r0tl01kq	364	9	were	be	VBD
cord-010027-r0tl01kq	364	10	serially	serially	RB
cord-010027-r0tl01kq	364	11	sectioned	section	VBN
cord-010027-r0tl01kq	364	12	at	at	IN
cord-010027-r0tl01kq	364	13	250	250	CD
cord-010027-r0tl01kq	364	14	µm	µm	CD
cord-010027-r0tl01kq	364	15	intervals	interval	NNS
cord-010027-r0tl01kq	364	16	.	.	.
cord-010027-r0tl01kq	365	1	Sections	section	NNS
cord-010027-r0tl01kq	365	2	were	be	VBD
cord-010027-r0tl01kq	365	3	stained	stain	VBN
cord-010027-r0tl01kq	365	4	with	with	IN
cord-010027-r0tl01kq	365	5	haematoxylin	haematoxylin	NNP
cord-010027-r0tl01kq	365	6	&	&	CC
cord-010027-r0tl01kq	365	7	eosin	eosin	NNP
cord-010027-r0tl01kq	365	8	,	,	,
cord-010027-r0tl01kq	365	9	Masson	Masson	NNP
cord-010027-r0tl01kq	365	10	's	's	POS
cord-010027-r0tl01kq	365	11	trichrome	trichrome	JJ
cord-010027-r0tl01kq	365	12	and	and	CC
cord-010027-r0tl01kq	365	13	Millers	Millers	NNP
cord-010027-r0tl01kq	365	14	'	'	POS
cord-010027-r0tl01kq	365	15	elastin	elastin	NN
cord-010027-r0tl01kq	365	16	,	,	,
cord-010027-r0tl01kq	365	17	from	from	IN
cord-010027-r0tl01kq	365	18	which	which	WDT
cord-010027-r0tl01kq	365	19	3D	3d	JJ
cord-010027-r0tl01kq	365	20	reconstructions	reconstruction	NNS
cord-010027-r0tl01kq	365	21	were	be	VBD
cord-010027-r0tl01kq	365	22	developed	develop	VBN
cord-010027-r0tl01kq	365	23	.	.	.
cord-010027-r0tl01kq	366	1	The	the	DT
cord-010027-r0tl01kq	366	2	ASC	ASC	NNP
cord-010027-r0tl01kq	366	3	is	be	VBZ
cord-010027-r0tl01kq	366	4	a	a	DT
cord-010027-r0tl01kq	366	5	complex	complex	JJ
cord-010027-r0tl01kq	366	6	structure	structure	NN
cord-010027-r0tl01kq	366	7	,	,	,
cord-010027-r0tl01kq	366	8	varying	vary	VBG
cord-010027-r0tl01kq	366	9	between	between	IN
cord-010027-r0tl01kq	366	10	individuals	individual	NNS
cord-010027-r0tl01kq	366	11	in	in	IN
cord-010027-r0tl01kq	366	12	the	the	DT
cord-010027-r0tl01kq	366	13	size	size	NN
cord-010027-r0tl01kq	366	14	and	and	CC
cord-010027-r0tl01kq	366	15	distribution	distribution	NN
cord-010027-r0tl01kq	366	16	of	of	IN
cord-010027-r0tl01kq	366	17	its	-PRON-	PRP$
cord-010027-r0tl01kq	366	18	layers	layer	NNS
cord-010027-r0tl01kq	366	19	with	with	IN
cord-010027-r0tl01kq	366	20	intermingling	intermingle	VBG
cord-010027-r0tl01kq	366	21	of	of	IN
cord-010027-r0tl01kq	366	22	fibres	fibre	NNS
cord-010027-r0tl01kq	366	23	and	and	CC
cord-010027-r0tl01kq	366	24	inconsistency	inconsistency	NN
cord-010027-r0tl01kq	366	25	of	of	IN
cord-010027-r0tl01kq	366	26	the	the	DT
cord-010027-r0tl01kq	366	27	longitudinal	longitudinal	JJ
cord-010027-r0tl01kq	366	28	smooth	smooth	JJ
cord-010027-r0tl01kq	366	29	muscle	muscle	NN
cord-010027-r0tl01kq	366	30	affecting	affect	VBG
cord-010027-r0tl01kq	366	31	the	the	DT
cord-010027-r0tl01kq	366	32	creation	creation	NN
cord-010027-r0tl01kq	366	33	of	of	IN
cord-010027-r0tl01kq	366	34	the	the	DT
cord-010027-r0tl01kq	366	35	surgical	surgical	JJ
cord-010027-r0tl01kq	366	36	intersphincteric	intersphincteric	JJ
cord-010027-r0tl01kq	366	37	plane	plane	NN
cord-010027-r0tl01kq	366	38	.	.	.
cord-010027-r0tl01kq	367	1	Longitudinal	longitudinal	JJ
cord-010027-r0tl01kq	367	2	fibres	fibre	NNS
cord-010027-r0tl01kq	367	3	penetrate	penetrate	VBP
cord-010027-r0tl01kq	367	4	the	the	DT
cord-010027-r0tl01kq	367	5	internal	internal	JJ
cord-010027-r0tl01kq	367	6	and	and	CC
cord-010027-r0tl01kq	367	7	external	external	JJ
cord-010027-r0tl01kq	367	8	anal	anal	JJ
cord-010027-r0tl01kq	367	9	sphincter	sphincter	NN
cord-010027-r0tl01kq	367	10	to	to	TO
cord-010027-r0tl01kq	367	11	anchor	anchor	VB
cord-010027-r0tl01kq	367	12	in	in	IN
cord-010027-r0tl01kq	367	13	the	the	DT
cord-010027-r0tl01kq	367	14	submucosa	submucosa	NNP
cord-010027-r0tl01kq	367	15	and	and	CC
cord-010027-r0tl01kq	367	16	ischiorectal	ischiorectal	JJ
cord-010027-r0tl01kq	367	17	fossa	fossa	NN
cord-010027-r0tl01kq	367	18	.	.	.
cord-010027-r0tl01kq	368	1	Striated	striated	JJ
cord-010027-r0tl01kq	368	2	muscle	muscle	NN
cord-010027-r0tl01kq	368	3	fibres	fibre	NNS
cord-010027-r0tl01kq	368	4	from	from	IN
cord-010027-r0tl01kq	368	5	the	the	DT
cord-010027-r0tl01kq	368	6	external	external	JJ
cord-010027-r0tl01kq	368	7	sphincter	sphincter	NN
cord-010027-r0tl01kq	368	8	were	be	VBD
cord-010027-r0tl01kq	368	9	identified	identify	VBN
cord-010027-r0tl01kq	368	10	in	in	IN
cord-010027-r0tl01kq	368	11	the	the	DT
cord-010027-r0tl01kq	368	12	submucosa	submucosa	NNP
cord-010027-r0tl01kq	368	13	in	in	IN
cord-010027-r0tl01kq	368	14	four	four	CD
cord-010027-r0tl01kq	368	15	of	of	IN
cord-010027-r0tl01kq	368	16	six	six	CD
cord-010027-r0tl01kq	368	17	specimens	specimen	NNS
cord-010027-r0tl01kq	368	18	.	.	.
cord-010027-r0tl01kq	369	1	The	the	DT
cord-010027-r0tl01kq	369	2	ASC	ASC	NNP
cord-010027-r0tl01kq	369	3	is	be	VBZ
cord-010027-r0tl01kq	369	4	highly	highly	RB
cord-010027-r0tl01kq	369	5	complex	complex	JJ
cord-010027-r0tl01kq	369	6	due	due	IN
cord-010027-r0tl01kq	369	7	to	to	IN
cord-010027-r0tl01kq	369	8	the	the	DT
cord-010027-r0tl01kq	369	9	degree	degree	NN
cord-010027-r0tl01kq	369	10	of	of	IN
cord-010027-r0tl01kq	369	11	variation	variation	NN
cord-010027-r0tl01kq	369	12	in	in	IN
cord-010027-r0tl01kq	369	13	its	-PRON-	PRP$
cord-010027-r0tl01kq	369	14	structure	structure	NN
cord-010027-r0tl01kq	369	15	and	and	CC
cord-010027-r0tl01kq	369	16	intermingling	intermingling	NN
cord-010027-r0tl01kq	369	17	of	of	IN
cord-010027-r0tl01kq	369	18	smooth	smooth	JJ
cord-010027-r0tl01kq	369	19	and	and	CC
cord-010027-r0tl01kq	369	20	striated	striated	JJ
cord-010027-r0tl01kq	369	21	muscle	muscle	NN
cord-010027-r0tl01kq	369	22	fibres	fibre	NNS
cord-010027-r0tl01kq	369	23	and	and	CC
cord-010027-r0tl01kq	369	24	their	-PRON-	PRP$
cord-010027-r0tl01kq	369	25	penetration	penetration	NN
cord-010027-r0tl01kq	369	26	of	of	IN
cord-010027-r0tl01kq	369	27	major	major	JJ
cord-010027-r0tl01kq	369	28	structures	structure	NNS
cord-010027-r0tl01kq	369	29	.	.	.
cord-010027-r0tl01kq	370	1	This	this	DT
cord-010027-r0tl01kq	370	2	creates	create	VBZ
cord-010027-r0tl01kq	370	3	potential	potential	JJ
cord-010027-r0tl01kq	370	4	tissue	tissue	NN
cord-010027-r0tl01kq	370	5	planes	plane	NNS
cord-010027-r0tl01kq	370	6	for	for	IN
cord-010027-r0tl01kq	370	7	the	the	DT
cord-010027-r0tl01kq	370	8	spread	spread	NN
cord-010027-r0tl01kq	370	9	of	of	IN
cord-010027-r0tl01kq	370	10	infection	infection	NN
cord-010027-r0tl01kq	370	11	,	,	,
cord-010027-r0tl01kq	370	12	fistula	fistula	NN
cord-010027-r0tl01kq	370	13	extension	extension	NN
cord-010027-r0tl01kq	370	14	and	and	CC
cord-010027-r0tl01kq	370	15	tumour	tumour	NN
cord-010027-r0tl01kq	370	16	spread	spread	NN
cord-010027-r0tl01kq	370	17	.	.	.
cord-010027-r0tl01kq	371	1	The	the	DT
cord-010027-r0tl01kq	371	2	complex	complex	JJ
cord-010027-r0tl01kq	371	3	anatomy	anatomy	NN
cord-010027-r0tl01kq	371	4	of	of	IN
cord-010027-r0tl01kq	371	5	the	the	DT
cord-010027-r0tl01kq	371	6	ASC	ASC	NNP
cord-010027-r0tl01kq	371	7	also	also	RB
cord-010027-r0tl01kq	371	8	impacts	impact	VBZ
cord-010027-r0tl01kq	371	9	on	on	IN
cord-010027-r0tl01kq	371	10	the	the	DT
cord-010027-r0tl01kq	371	11	staging	staging	NN
cord-010027-r0tl01kq	371	12	of	of	IN
cord-010027-r0tl01kq	371	13	low	low	JJ
cord-010027-r0tl01kq	371	14	rectal	rectal	JJ
cord-010027-r0tl01kq	371	15	cancers	cancer	NNS
cord-010027-r0tl01kq	371	16	in	in	IN
cord-010027-r0tl01kq	371	17	this	this	DT
cord-010027-r0tl01kq	371	18	region	region	NN
cord-010027-r0tl01kq	371	19	,	,	,
cord-010027-r0tl01kq	371	20	which	which	WDT
cord-010027-r0tl01kq	371	21	requires	require	VBZ
cord-010027-r0tl01kq	371	22	further	further	JJ
cord-010027-r0tl01kq	371	23	investigation	investigation	NN
cord-010027-r0tl01kq	371	24	.	.	.
cord-010027-r0tl01kq	372	1	P	p	NN
cord-010027-r0tl01kq	372	2	H	H	NNP
cord-010027-r0tl01kq	372	3	Thorpe	Thorpe	NNP
cord-010027-r0tl01kq	372	4	;	;	:
cord-010027-r0tl01kq	372	5	A	a	DT
cord-010027-r0tl01kq	372	6	Asiri	Asiri	NNP
cord-010027-r0tl01kq	372	7	;	;	:
cord-010027-r0tl01kq	372	8	M	M	NNP
cord-010027-r0tl01kq	372	9	Akhlaq	Akhlaq	NNP
cord-010027-r0tl01kq	372	10	;	;	:
cord-010027-r0tl01kq	372	11	D	D	NNP
cord-010027-r0tl01kq	372	12	Jackson	Jackson	NNP
cord-010027-r0tl01kq	373	1	;	;	:
cord-010027-r0tl01kq	373	2	M	M	NNP
cord-010027-r0tl01kq	373	3	Ilyas	Ilyas	NNP
cord-010027-r0tl01kq	373	4	Cten	Cten	NNP
cord-010027-r0tl01kq	373	5	is	be	VBZ
cord-010027-r0tl01kq	373	6	upregulated	upregulate	VBN
cord-010027-r0tl01kq	373	7	in	in	IN
cord-010027-r0tl01kq	373	8	a	a	DT
cord-010027-r0tl01kq	373	9	number	number	NN
cord-010027-r0tl01kq	373	10	of	of	IN
cord-010027-r0tl01kq	373	11	tumour	tumour	NN
cord-010027-r0tl01kq	373	12	types	type	NNS
cord-010027-r0tl01kq	373	13	and	and	CC
cord-010027-r0tl01kq	373	14	in	in	IN
cord-010027-r0tl01kq	373	15	colorectal	colorectal	JJ
cord-010027-r0tl01kq	373	16	cancer	cancer	NN
cord-010027-r0tl01kq	373	17	expression	expression	NN
cord-010027-r0tl01kq	373	18	is	be	VBZ
cord-010027-r0tl01kq	373	19	associated	associate	VBN
cord-010027-r0tl01kq	373	20	with	with	IN
cord-010027-r0tl01kq	373	21	advanced	advanced	JJ
cord-010027-r0tl01kq	373	22	Dukes	Dukes	NNP
cord-010027-r0tl01kq	373	23	stage	stage	NN
cord-010027-r0tl01kq	373	24	,	,	,
cord-010027-r0tl01kq	373	25	poor	poor	JJ
cord-010027-r0tl01kq	373	26	prognosis	prognosis	NN
cord-010027-r0tl01kq	373	27	and	and	CC
cord-010027-r0tl01kq	373	28	distant	distant	JJ
cord-010027-r0tl01kq	373	29	metastasis	metastasis	NN
cord-010027-r0tl01kq	373	30	.	.	.
cord-010027-r0tl01kq	374	1	Cten	Cten	NNP
cord-010027-r0tl01kq	374	2	is	be	VBZ
cord-010027-r0tl01kq	374	3	localised	localise	VBN
cord-010027-r0tl01kq	374	4	at	at	IN
cord-010027-r0tl01kq	374	5	focal	focal	JJ
cord-010027-r0tl01kq	374	6	adhesions	adhesion	NNS
cord-010027-r0tl01kq	374	7	and	and	CC
cord-010027-r0tl01kq	374	8	regulates	regulate	VBZ
cord-010027-r0tl01kq	374	9	cell	cell	NN
cord-010027-r0tl01kq	374	10	motility	motility	NN
cord-010027-r0tl01kq	374	11	but	but	CC
cord-010027-r0tl01kq	374	12	knowledge	knowledge	NN
cord-010027-r0tl01kq	374	13	of	of	IN
cord-010027-r0tl01kq	374	14	underlying	underlie	VBG
cord-010027-r0tl01kq	374	15	signalling	signalling	NN
cord-010027-r0tl01kq	374	16	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	374	17	is	be	VBZ
cord-010027-r0tl01kq	374	18	sparse	sparse	JJ
cord-010027-r0tl01kq	374	19	.	.	.
cord-010027-r0tl01kq	375	1	Epithelial	epithelial	JJ
cord-010027-r0tl01kq	375	2	to	to	IN
cord-010027-r0tl01kq	375	3	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	375	4	transition	transition	NN
cord-010027-r0tl01kq	375	5	(	(	-LRB-
cord-010027-r0tl01kq	375	6	EMT	EMT	NNP
cord-010027-r0tl01kq	375	7	)	)	-RRB-
cord-010027-r0tl01kq	375	8	is	be	VBZ
cord-010027-r0tl01kq	375	9	a	a	DT
cord-010027-r0tl01kq	375	10	process	process	NN
cord-010027-r0tl01kq	375	11	whereby	whereby	WRB
cord-010027-r0tl01kq	375	12	cells	cell	NNS
cord-010027-r0tl01kq	375	13	acquire	acquire	VBP
cord-010027-r0tl01kq	375	14	an	an	DT
cord-010027-r0tl01kq	375	15	invasive	invasive	JJ
cord-010027-r0tl01kq	375	16	phenotype	phenotype	NN
cord-010027-r0tl01kq	375	17	to	to	TO
cord-010027-r0tl01kq	375	18	aid	aid	VB
cord-010027-r0tl01kq	375	19	cell	cell	NN
cord-010027-r0tl01kq	375	20	migration	migration	NN
cord-010027-r0tl01kq	375	21	and	and	CC
cord-010027-r0tl01kq	375	22	is	be	VBZ
cord-010027-r0tl01kq	375	23	found	find	VBN
cord-010027-r0tl01kq	375	24	to	to	TO
cord-010027-r0tl01kq	375	25	occur	occur	VB
cord-010027-r0tl01kq	375	26	in	in	IN
cord-010027-r0tl01kq	375	27	a	a	DT
cord-010027-r0tl01kq	375	28	number	number	NN
cord-010027-r0tl01kq	375	29	of	of	IN
cord-010027-r0tl01kq	375	30	biological	biological	JJ
cord-010027-r0tl01kq	375	31	processes	process	NNS
cord-010027-r0tl01kq	375	32	including	include	VBG
cord-010027-r0tl01kq	375	33	cancer	cancer	NN
cord-010027-r0tl01kq	375	34	metastasis	metastasis	NN
cord-010027-r0tl01kq	375	35	.	.	.
cord-010027-r0tl01kq	376	1	We	-PRON-	PRP
cord-010027-r0tl01kq	376	2	investigated	investigate	VBD
cord-010027-r0tl01kq	376	3	whether	whether	IN
cord-010027-r0tl01kq	376	4	Cten	Cten	NNP
cord-010027-r0tl01kq	376	5	increases	increase	VBZ
cord-010027-r0tl01kq	376	6	cell	cell	NN
cord-010027-r0tl01kq	376	7	migration	migration	NN
cord-010027-r0tl01kq	376	8	through	through	IN
cord-010027-r0tl01kq	376	9	EMT	EMT	NNP
cord-010027-r0tl01kq	376	10	pathways	pathway	NNS
cord-010027-r0tl01kq	376	11	in	in	IN
cord-010027-r0tl01kq	376	12	colorectal	colorectal	JJ
cord-010027-r0tl01kq	376	13	cancer	cancer	NN
cord-010027-r0tl01kq	376	14	.	.	.
cord-010027-r0tl01kq	377	1	Cten	Cten	NNP
cord-010027-r0tl01kq	377	2	was	be	VBD
cord-010027-r0tl01kq	377	3	forcibly	forcibly	RB
cord-010027-r0tl01kq	377	4	expressed	express	VBN
cord-010027-r0tl01kq	377	5	in	in	IN
cord-010027-r0tl01kq	377	6	colorectal	colorectal	JJ
cord-010027-r0tl01kq	377	7	cell	cell	NN
cord-010027-r0tl01kq	377	8	lines	line	NNS
cord-010027-r0tl01kq	377	9	and	and	CC
cord-010027-r0tl01kq	377	10	Snail	Snail	NNP
cord-010027-r0tl01kq	377	11	expression	expression	NN
cord-010027-r0tl01kq	377	12	determined	determine	VBN
cord-010027-r0tl01kq	377	13	by	by	IN
cord-010027-r0tl01kq	377	14	qPCR	qPCR	NNP
cord-010027-r0tl01kq	377	15	and	and	CC
cord-010027-r0tl01kq	377	16	western	western	JJ
cord-010027-r0tl01kq	377	17	blot	blot	NN
cord-010027-r0tl01kq	377	18	.	.	.
cord-010027-r0tl01kq	378	1	The	the	DT
cord-010027-r0tl01kq	378	2	cycloheximide	cycloheximide	NN
cord-010027-r0tl01kq	378	3	pulse	pulse	NN
cord-010027-r0tl01kq	378	4	chase	chase	NN
cord-010027-r0tl01kq	378	5	assay	assay	NN
cord-010027-r0tl01kq	378	6	was	be	VBD
cord-010027-r0tl01kq	378	7	used	use	VBN
cord-010027-r0tl01kq	378	8	to	to	TO
cord-010027-r0tl01kq	378	9	assess	assess	VB
cord-010027-r0tl01kq	378	10	any	any	DT
cord-010027-r0tl01kq	378	11	changes	change	NNS
cord-010027-r0tl01kq	378	12	in	in	IN
cord-010027-r0tl01kq	378	13	Snail	Snail	NNP
cord-010027-r0tl01kq	378	14	protein	protein	NN
cord-010027-r0tl01kq	378	15	stability	stability	NN
cord-010027-r0tl01kq	378	16	.	.	.
cord-010027-r0tl01kq	379	1	Further	further	RB
cord-010027-r0tl01kq	379	2	to	to	IN
cord-010027-r0tl01kq	379	3	this	this	DT
cord-010027-r0tl01kq	379	4	,	,	,
cord-010027-r0tl01kq	379	5	the	the	DT
cord-010027-r0tl01kq	379	6	Transwell	Transwell	NNP
cord-010027-r0tl01kq	379	7	migration	migration	NN
cord-010027-r0tl01kq	379	8	assay	assay	NN
cord-010027-r0tl01kq	379	9	was	be	VBD
cord-010027-r0tl01kq	379	10	performed	perform	VBN
cord-010027-r0tl01kq	379	11	to	to	TO
cord-010027-r0tl01kq	379	12	investigate	investigate	VB
cord-010027-r0tl01kq	379	13	changes	change	NNS
cord-010027-r0tl01kq	379	14	in	in	IN
cord-010027-r0tl01kq	379	15	cell	cell	NN
cord-010027-r0tl01kq	379	16	motility	motility	NN
cord-010027-r0tl01kq	379	17	.	.	.
cord-010027-r0tl01kq	380	1	Forced	force	VBN
cord-010027-r0tl01kq	380	2	expression	expression	NN
cord-010027-r0tl01kq	380	3	of	of	IN
cord-010027-r0tl01kq	380	4	Cten	Cten	NNP
cord-010027-r0tl01kq	380	5	was	be	VBD
cord-010027-r0tl01kq	380	6	shown	show	VBN
cord-010027-r0tl01kq	380	7	to	to	TO
cord-010027-r0tl01kq	380	8	increase	increase	VB
cord-010027-r0tl01kq	380	9	Snail	Snail	NNP
cord-010027-r0tl01kq	380	10	protein	protein	NN
cord-010027-r0tl01kq	380	11	expression	expression	NN
cord-010027-r0tl01kq	380	12	in	in	IN
cord-010027-r0tl01kq	380	13	HCT116	HCT116	NNP
cord-010027-r0tl01kq	380	14	and	and	CC
cord-010027-r0tl01kq	380	15	Caco2	caco2	JJ
cord-010027-r0tl01kq	380	16	cell	cell	NN
cord-010027-r0tl01kq	380	17	lines	line	NNS
cord-010027-r0tl01kq	380	18	.	.	.
cord-010027-r0tl01kq	381	1	There	there	EX
cord-010027-r0tl01kq	381	2	was	be	VBD
cord-010027-r0tl01kq	381	3	no	no	DT
cord-010027-r0tl01kq	381	4	change	change	NN
cord-010027-r0tl01kq	381	5	in	in	IN
cord-010027-r0tl01kq	381	6	the	the	DT
cord-010027-r0tl01kq	381	7	level	level	NN
cord-010027-r0tl01kq	381	8	of	of	IN
cord-010027-r0tl01kq	381	9	Snail	Snail	NNP
cord-010027-r0tl01kq	381	10	mRNA	mRNA	NNP
cord-010027-r0tl01kq	381	11	suggesting	suggest	VBG
cord-010027-r0tl01kq	381	12	that	that	IN
cord-010027-r0tl01kq	381	13	Cten	Cten	NNP
cord-010027-r0tl01kq	381	14	regulates	regulate	VBZ
cord-010027-r0tl01kq	381	15	Snail	Snail	NNP
cord-010027-r0tl01kq	381	16	at	at	IN
cord-010027-r0tl01kq	381	17	a	a	DT
cord-010027-r0tl01kq	381	18	post	post	JJ
cord-010027-r0tl01kq	381	19	transcriptional	transcriptional	JJ
cord-010027-r0tl01kq	381	20	level	level	NN
cord-010027-r0tl01kq	381	21	.	.	.
cord-010027-r0tl01kq	382	1	Inhibition	inhibition	NN
cord-010027-r0tl01kq	382	2	of	of	IN
cord-010027-r0tl01kq	382	3	protein	protein	NN
cord-010027-r0tl01kq	382	4	synthesis	synthesis	NN
cord-010027-r0tl01kq	382	5	confirmed	confirm	VBD
cord-010027-r0tl01kq	382	6	this	this	DT
cord-010027-r0tl01kq	382	7	and	and	CC
cord-010027-r0tl01kq	382	8	showed	show	VBD
cord-010027-r0tl01kq	382	9	that	that	IN
cord-010027-r0tl01kq	382	10	Cten	Cten	NNP
cord-010027-r0tl01kq	382	11	regulates	regulate	VBZ
cord-010027-r0tl01kq	382	12	the	the	DT
cord-010027-r0tl01kq	382	13	stability	stability	NN
cord-010027-r0tl01kq	382	14	of	of	IN
cord-010027-r0tl01kq	382	15	Snail	Snail	NNP
cord-010027-r0tl01kq	382	16	protein	protein	NN
cord-010027-r0tl01kq	382	17	.	.	.
cord-010027-r0tl01kq	383	1	Simultaneous	simultaneous	JJ
cord-010027-r0tl01kq	383	2	forced	force	VBN
cord-010027-r0tl01kq	383	3	expression	expression	NN
cord-010027-r0tl01kq	383	4	of	of	IN
cord-010027-r0tl01kq	383	5	Cten	Cten	NNP
cord-010027-r0tl01kq	383	6	and	and	CC
cord-010027-r0tl01kq	383	7	knockdown	knockdown	NN
cord-010027-r0tl01kq	383	8	of	of	IN
cord-010027-r0tl01kq	383	9	Snail	Snail	NNP
cord-010027-r0tl01kq	383	10	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	383	11	that	that	IN
cord-010027-r0tl01kq	383	12	this	this	DT
cord-010027-r0tl01kq	383	13	relationship	relationship	NN
cord-010027-r0tl01kq	383	14	was	be	VBD
cord-010027-r0tl01kq	383	15	functionally	functionally	RB
cord-010027-r0tl01kq	383	16	active	active	JJ
cord-010027-r0tl01kq	383	17	.	.	.
cord-010027-r0tl01kq	384	1	Forced	force	VBN
cord-010027-r0tl01kq	384	2	expression	expression	NN
cord-010027-r0tl01kq	384	3	of	of	IN
cord-010027-r0tl01kq	384	4	Cten	Cten	NNP
cord-010027-r0tl01kq	384	5	increased	increase	VBD
cord-010027-r0tl01kq	384	6	cell	cell	NN
cord-010027-r0tl01kq	384	7	migration	migration	NN
cord-010027-r0tl01kq	384	8	(	(	-LRB-
cord-010027-r0tl01kq	384	9	p<0.05	p<0.05	CD
cord-010027-r0tl01kq	384	10	)	)	-RRB-
cord-010027-r0tl01kq	384	11	which	which	WDT
cord-010027-r0tl01kq	384	12	was	be	VBD
cord-010027-r0tl01kq	384	13	subsequently	subsequently	RB
cord-010027-r0tl01kq	384	14	lost	lose	VBN
cord-010027-r0tl01kq	384	15	when	when	WRB
cord-010027-r0tl01kq	384	16	Snail	Snail	NNP
cord-010027-r0tl01kq	384	17	was	be	VBD
cord-010027-r0tl01kq	384	18	knocked	knock	VBN
cord-010027-r0tl01kq	384	19	down	down	RP
cord-010027-r0tl01kq	384	20	(	(	-LRB-
cord-010027-r0tl01kq	384	21	p<0.001	p<0.001	CD
cord-010027-r0tl01kq	384	22	)	)	-RRB-
cord-010027-r0tl01kq	384	23	.	.	.
cord-010027-r0tl01kq	385	1	We	-PRON-	PRP
cord-010027-r0tl01kq	385	2	are	be	VBP
cord-010027-r0tl01kq	385	3	the	the	DT
cord-010027-r0tl01kq	385	4	first	first	JJ
cord-010027-r0tl01kq	385	5	to	to	TO
cord-010027-r0tl01kq	385	6	identify	identify	VB
cord-010027-r0tl01kq	385	7	Snail	Snail	NNP
cord-010027-r0tl01kq	385	8	as	as	IN
cord-010027-r0tl01kq	385	9	a	a	DT
cord-010027-r0tl01kq	385	10	downstream	downstream	JJ
cord-010027-r0tl01kq	385	11	target	target	NN
cord-010027-r0tl01kq	385	12	of	of	IN
cord-010027-r0tl01kq	385	13	Cten	Cten	NNP
cord-010027-r0tl01kq	385	14	signalling	signal	VBG
cord-010027-r0tl01kq	385	15	.	.	.
cord-010027-r0tl01kq	386	1	This	this	DT
cord-010027-r0tl01kq	386	2	finding	finding	NN
cord-010027-r0tl01kq	386	3	advances	advance	VBZ
cord-010027-r0tl01kq	386	4	the	the	DT
cord-010027-r0tl01kq	386	5	understanding	understanding	NN
cord-010027-r0tl01kq	386	6	of	of	IN
cord-010027-r0tl01kq	386	7	cancer	cancer	NN
cord-010027-r0tl01kq	386	8	cell	cell	NN
cord-010027-r0tl01kq	386	9	motility	motility	NN
cord-010027-r0tl01kq	386	10	regulatory	regulatory	JJ
cord-010027-r0tl01kq	386	11	networks	network	NNS
cord-010027-r0tl01kq	386	12	and	and	CC
cord-010027-r0tl01kq	386	13	further	further	JJ
cord-010027-r0tl01kq	386	14	highlights	highlight	NNS
cord-010027-r0tl01kq	386	15	Cten	Cten	NNP
cord-010027-r0tl01kq	386	16	as	as	IN
cord-010027-r0tl01kq	386	17	a	a	DT
cord-010027-r0tl01kq	386	18	potential	potential	JJ
cord-010027-r0tl01kq	386	19	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	386	20	target	target	NN
cord-010027-r0tl01kq	386	21	in	in	IN
cord-010027-r0tl01kq	386	22	colorectal	colorectal	JJ
cord-010027-r0tl01kq	386	23	cancer	cancer	NN
cord-010027-r0tl01kq	386	24	.	.	.
cord-010027-r0tl01kq	387	1	Work	work	NN
cord-010027-r0tl01kq	387	2	supported	support	VBN
cord-010027-r0tl01kq	387	3	by	by	IN
cord-010027-r0tl01kq	387	4	a	a	DT
cord-010027-r0tl01kq	387	5	Pathological	Pathological	NNP
cord-010027-r0tl01kq	387	6	Society	Society	NNP
cord-010027-r0tl01kq	387	7	grant	grant	NN
cord-010027-r0tl01kq	387	8	.	.	.
cord-010027-r0tl01kq	388	1	Treatment	treatment	NN
cord-010027-r0tl01kq	388	2	Strategies	strategy	NNS
cord-010027-r0tl01kq	388	3	for	for	IN
cord-010027-r0tl01kq	388	4	Patients	patient	NNS
cord-010027-r0tl01kq	388	5	with	with	IN
cord-010027-r0tl01kq	388	6	Advanced	Advanced	NNP
cord-010027-r0tl01kq	388	7	Colorectal	Colorectal	NNP
cord-010027-r0tl01kq	388	8	Cancer	Cancer	NNP
cord-010027-r0tl01kq	388	9	P	P	NNP
cord-010027-r0tl01kq	388	10	SD	SD	NNP
cord-010027-r0tl01kq	388	11	Richman	Richman	NNP
cord-010027-r0tl01kq	388	12	1	1	CD
cord-010027-r0tl01kq	388	13	;	;	:
cord-010027-r0tl01kq	388	14	GJ	GJ	NNP
cord-010027-r0tl01kq	388	15	Hemmings	Hemmings	NNP
cord-010027-r0tl01kq	388	16	1	1	CD
cord-010027-r0tl01kq	388	17	;	;	:
cord-010027-r0tl01kq	388	18	P	p	NN
cord-010027-r0tl01kq	388	19	Chambers	chamber	NNS
cord-010027-r0tl01kq	388	20	1	1	CD
cord-010027-r0tl01kq	388	21	;	;	:
cord-010027-r0tl01kq	388	22	M	M	NNP
cord-010027-r0tl01kq	388	23	Taylor	Taylor	NNP
cord-010027-r0tl01kq	388	24	1	1	CD
cord-010027-r0tl01kq	388	25	;	;	:
cord-010027-r0tl01kq	388	26	HM	HM	NNP
cord-010027-r0tl01kq	388	27	Wood	Wood	NNP
cord-010027-r0tl01kq	388	28	1	1	CD
cord-010027-r0tl01kq	388	29	;	;	:
cord-010027-r0tl01kq	388	30	E	E	NNP
cord-010027-r0tl01kq	388	31	Tinkler	Tinkler	NNP
cord-010027-r0tl01kq	388	32	-	-	HYPH
cord-010027-r0tl01kq	388	33	Hundal	Hundal	NNP
cord-010027-r0tl01kq	388	34	1	1	CD
cord-010027-r0tl01kq	388	35	;	;	:
cord-010027-r0tl01kq	389	1	K	K	NNP
cord-010027-r0tl01kq	389	2	Southward	Southward	NNP
cord-010027-r0tl01kq	389	3	1	1	CD
cord-010027-r0tl01kq	389	4	;	;	:
cord-010027-r0tl01kq	389	5	JM	JM	NNP
cord-010027-r0tl01kq	389	6	Foster	Foster	NNP
cord-010027-r0tl01kq	389	7	2	2	CD
cord-010027-r0tl01kq	389	8	;	;	:
cord-010027-r0tl01kq	389	9	A	a	DT
cord-010027-r0tl01kq	389	10	Ouime	Ouime	NNP
cord-010027-r0tl01kq	389	11	2	2	CD
cord-010027-r0tl01kq	389	12	;	;	:
cord-010027-r0tl01kq	389	13	KG	KG	NNP
cord-010027-r0tl01kq	389	14	Spink	Spink	NNP
cord-010027-r0tl01kq	389	15	2	2	CD
cord-010027-r0tl01kq	389	16	;	;	:
cord-010027-r0tl01kq	389	17	P	P	NNP
cord-010027-r0tl01kq	389	18	Quirke	Quirke	NNP
cord-010027-r0tl01kq	389	19	1	1	CD
cord-010027-r0tl01kq	389	20	1	1	CD
cord-010027-r0tl01kq	389	21	Leeds	Leeds	NNP
cord-010027-r0tl01kq	389	22	Institute	Institute	NNP
cord-010027-r0tl01kq	389	23	of	of	IN
cord-010027-r0tl01kq	389	24	Cancer	Cancer	NNP
cord-010027-r0tl01kq	389	25	and	and	CC
cord-010027-r0tl01kq	389	26	Pathology	Pathology	NNP
cord-010027-r0tl01kq	389	27	,	,	,
cord-010027-r0tl01kq	389	28	Leeds	Leeds	NNP
cord-010027-r0tl01kq	389	29	,	,	,
cord-010027-r0tl01kq	389	30	UK	UK	NNP
cord-010027-r0tl01kq	389	31	;	;	:
cord-010027-r0tl01kq	389	32	2	2	CD
cord-010027-r0tl01kq	389	33	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	389	34	,	,	,
cord-010027-r0tl01kq	389	35	High	High	NNP
cord-010027-r0tl01kq	389	36	Wycombe	Wycombe	NNP
cord-010027-r0tl01kq	389	37	,	,	,
cord-010027-r0tl01kq	389	38	UK	UK	NNP
cord-010027-r0tl01kq	389	39	Treatment	Treatment	NNP
cord-010027-r0tl01kq	389	40	for	for	IN
cord-010027-r0tl01kq	389	41	advanced	advanced	JJ
cord-010027-r0tl01kq	389	42	colorectal	colorectal	JJ
cord-010027-r0tl01kq	389	43	cancer	cancer	NN
cord-010027-r0tl01kq	389	44	is	be	VBZ
cord-010027-r0tl01kq	389	45	moving	move	VBG
cord-010027-r0tl01kq	389	46	to	to	IN
cord-010027-r0tl01kq	389	47	combination	combination	NN
cord-010027-r0tl01kq	389	48	therapies	therapy	NNS
cord-010027-r0tl01kq	389	49	,	,	,
cord-010027-r0tl01kq	389	50	targeting	target	VBG
cord-010027-r0tl01kq	389	51	multiple	multiple	JJ
cord-010027-r0tl01kq	389	52	signalling	signal	VBG
cord-010027-r0tl01kq	389	53	pathways	pathway	NNS
cord-010027-r0tl01kq	389	54	.	.	.
cord-010027-r0tl01kq	390	1	Indeed	indeed	RB
cord-010027-r0tl01kq	390	2	,	,	,
cord-010027-r0tl01kq	390	3	MRC	MRC	NNP
cord-010027-r0tl01kq	390	4	FOCUS4	FOCUS4	NNP
cord-010027-r0tl01kq	390	5	has	have	VBZ
cord-010027-r0tl01kq	390	6	been	be	VBN
cord-010027-r0tl01kq	390	7	designed	design	VBN
cord-010027-r0tl01kq	390	8	to	to	TO
cord-010027-r0tl01kq	390	9	assess	assess	VB
cord-010027-r0tl01kq	390	10	this	this	DT
cord-010027-r0tl01kq	390	11	.	.	.
cord-010027-r0tl01kq	391	1	We	-PRON-	PRP
cord-010027-r0tl01kq	391	2	determined	determine	VBD
cord-010027-r0tl01kq	391	3	pTEN	pten	NN
cord-010027-r0tl01kq	391	4	protein	protein	NN
cord-010027-r0tl01kq	391	5	expression	expression	NN
cord-010027-r0tl01kq	391	6	,	,	,
cord-010027-r0tl01kq	391	7	and	and	CC
cord-010027-r0tl01kq	391	8	assessed	assess	VBD
cord-010027-r0tl01kq	391	9	this	this	DT
cord-010027-r0tl01kq	391	10	in	in	IN
cord-010027-r0tl01kq	391	11	relation	relation	NN
cord-010027-r0tl01kq	391	12	to	to	IN
cord-010027-r0tl01kq	391	13	other	other	JJ
cord-010027-r0tl01kq	391	14	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	391	15	associated	associate	VBN
cord-010027-r0tl01kq	391	16	with	with	IN
cord-010027-r0tl01kq	391	17	signalling	signal	VBG
cord-010027-r0tl01kq	391	18	downstream	downstream	NN
cord-010027-r0tl01kq	391	19	of	of	IN
cord-010027-r0tl01kq	391	20	the	the	DT
cord-010027-r0tl01kq	391	21	epidermal	epidermal	JJ
cord-010027-r0tl01kq	391	22	growth	growth	NN
cord-010027-r0tl01kq	391	23	factor	factor	NN
cord-010027-r0tl01kq	391	24	receptor	receptor	NN
cord-010027-r0tl01kq	391	25	.	.	.
cord-010027-r0tl01kq	392	1	Tissue	tissue	NN
cord-010027-r0tl01kq	392	2	microarrays	microarray	NNS
cord-010027-r0tl01kq	392	3	were	be	VBD
cord-010027-r0tl01kq	392	4	constructed	construct	VBN
cord-010027-r0tl01kq	392	5	from	from	IN
cord-010027-r0tl01kq	392	6	2	2	CD
cord-010027-r0tl01kq	392	7	advanced	advanced	JJ
cord-010027-r0tl01kq	392	8	colorectal	colorectal	JJ
cord-010027-r0tl01kq	392	9	cancer	cancer	NN
cord-010027-r0tl01kq	392	10	(	(	-LRB-
cord-010027-r0tl01kq	392	11	aCRC	acrc	JJ
cord-010027-r0tl01kq	392	12	)	)	-RRB-
cord-010027-r0tl01kq	392	13	clinical	clinical	JJ
cord-010027-r0tl01kq	392	14	trials	trial	NNS
cord-010027-r0tl01kq	392	15	(	(	-LRB-
cord-010027-r0tl01kq	392	16	FOCUS	FOCUS	NNP
cord-010027-r0tl01kq	392	17	and	and	CC
cord-010027-r0tl01kq	392	18	PICCOLO	PICCOLO	NNP
cord-010027-r0tl01kq	392	19	)	)	-RRB-
cord-010027-r0tl01kq	392	20	for	for	IN
cord-010027-r0tl01kq	392	21	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	392	22	(	(	-LRB-
cord-010027-r0tl01kq	392	23	IHC	IHC	NNP
cord-010027-r0tl01kq	392	24	)	)	-RRB-
cord-010027-r0tl01kq	392	25	.	.	.
cord-010027-r0tl01kq	393	1	Mutation	mutation	NN
cord-010027-r0tl01kq	393	2	status	status	NN
cord-010027-r0tl01kq	393	3	of	of	IN
cord-010027-r0tl01kq	393	4	KRAS	KRAS	NNP
cord-010027-r0tl01kq	393	5	,	,	,
cord-010027-r0tl01kq	393	6	NRAS	NRAS	NNP
cord-010027-r0tl01kq	393	7	,	,	,
cord-010027-r0tl01kq	393	8	PIK3CA	pik3ca	NN
cord-010027-r0tl01kq	393	9	and	and	CC
cord-010027-r0tl01kq	393	10	BRAF	BRAF	NNP
cord-010027-r0tl01kq	393	11	was	be	VBD
cord-010027-r0tl01kq	393	12	assessed	assess	VBN
cord-010027-r0tl01kq	393	13	by	by	IN
cord-010027-r0tl01kq	393	14	pyrosequencing	pyrosequence	VBG
cord-010027-r0tl01kq	393	15	.	.	.
cord-010027-r0tl01kq	394	1	Copy	copy	JJ
cord-010027-r0tl01kq	394	2	number	number	NN
cord-010027-r0tl01kq	394	3	variation	variation	NN
cord-010027-r0tl01kq	394	4	was	be	VBD
cord-010027-r0tl01kq	394	5	assessed	assess	VBN
cord-010027-r0tl01kq	394	6	on	on	IN
cord-010027-r0tl01kq	394	7	Oncoscan	Oncoscan	NNP
cord-010027-r0tl01kq	394	8	®	®	POS
cord-010027-r0tl01kq	394	9	FFPE	FFPE	NNP
cord-010027-r0tl01kq	394	10	Assay	Assay	NNP
cord-010027-r0tl01kq	394	11	Kit	kit	NN
cord-010027-r0tl01kq	394	12	(	(	-LRB-
cord-010027-r0tl01kq	394	13	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	394	14	Inc.	Inc.	NNP
cord-010027-r0tl01kq	394	15	)	)	-RRB-
cord-010027-r0tl01kq	394	16	.	.	.
cord-010027-r0tl01kq	395	1	pTEN	pTEN	NNP
cord-010027-r0tl01kq	395	2	protein	protein	NNP
cord-010027-r0tl01kq	395	3	expression	expression	NN
cord-010027-r0tl01kq	395	4	was	be	VBD
cord-010027-r0tl01kq	395	5	correlated	correlate	VBN
cord-010027-r0tl01kq	395	6	with	with	IN
cord-010027-r0tl01kq	395	7	mutation	mutation	NN
cord-010027-r0tl01kq	395	8	status	status	NN
cord-010027-r0tl01kq	395	9	,	,	,
cord-010027-r0tl01kq	395	10	MMR	MMR	NNP
cord-010027-r0tl01kq	395	11	status	status	NN
cord-010027-r0tl01kq	395	12	,	,	,
cord-010027-r0tl01kq	395	13	primary	primary	JJ
cord-010027-r0tl01kq	395	14	tumour	tumour	NN
cord-010027-r0tl01kq	395	15	location	location	NN
cord-010027-r0tl01kq	395	16	and	and	CC
cord-010027-r0tl01kq	395	17	copy	copy	NN
cord-010027-r0tl01kq	395	18	number	number	NN
cord-010027-r0tl01kq	395	19	.	.	.
cord-010027-r0tl01kq	396	1	pTEN	pTEN	NNP
cord-010027-r0tl01kq	396	2	protein	protein	NN
cord-010027-r0tl01kq	396	3	expression	expression	NN
cord-010027-r0tl01kq	396	4	for	for	IN
cord-010027-r0tl01kq	396	5	1288	1288	CD
cord-010027-r0tl01kq	396	6	patients	patient	NNS
cord-010027-r0tl01kq	396	7	showed	show	VBD
cord-010027-r0tl01kq	396	8	complete	complete	JJ
cord-010027-r0tl01kq	396	9	loss	loss	NN
cord-010027-r0tl01kq	396	10	of	of	IN
cord-010027-r0tl01kq	396	11	expression	expression	NN
cord-010027-r0tl01kq	396	12	in	in	IN
cord-010027-r0tl01kq	396	13	85/787	85/787	CD
cord-010027-r0tl01kq	396	14	(	(	-LRB-
cord-010027-r0tl01kq	396	15	10.8	10.8	CD
cord-010027-r0tl01kq	396	16	%	%	NN
cord-010027-r0tl01kq	396	17	)	)	-RRB-
cord-010027-r0tl01kq	396	18	-FOCUS	-FOCUS	.
cord-010027-r0tl01kq	397	1	and	and	CC
cord-010027-r0tl01kq	397	2	64/501	64/501	CD
cord-010027-r0tl01kq	397	3	(	(	-LRB-
cord-010027-r0tl01kq	397	4	12.8	12.8	CD
cord-010027-r0tl01kq	397	5	%	%	NN
cord-010027-r0tl01kq	397	6	)	)	-RRB-
cord-010027-r0tl01kq	398	1	-PICCOLO	-PICCOLO	.
cord-010027-r0tl01kq	398	2	.	.	.
cord-010027-r0tl01kq	399	1	BRAF	BRAF	NNP
cord-010027-r0tl01kq	399	2	mutation	mutation	NN
cord-010027-r0tl01kq	399	3	status	status	NN
cord-010027-r0tl01kq	399	4	was	be	VBD
cord-010027-r0tl01kq	399	5	significantly	significantly	RB
cord-010027-r0tl01kq	399	6	different	different	JJ
cord-010027-r0tl01kq	399	7	between	between	IN
cord-010027-r0tl01kq	399	8	the	the	DT
cord-010027-r0tl01kq	399	9	pTEN	pten	JJ
cord-010027-r0tl01kq	399	10	negative	negative	JJ
cord-010027-r0tl01kq	399	11	and	and	CC
cord-010027-r0tl01kq	399	12	pTEN	pten	JJ
cord-010027-r0tl01kq	399	13	positive	positive	JJ
cord-010027-r0tl01kq	399	14	populations	population	NNS
cord-010027-r0tl01kq	399	15	(	(	-LRB-
cord-010027-r0tl01kq	399	16	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	399	17	)	)	-RRB-
cord-010027-r0tl01kq	399	18	,	,	,
cord-010027-r0tl01kq	399	19	with	with	IN
cord-010027-r0tl01kq	399	20	significantly	significantly	RB
cord-010027-r0tl01kq	399	21	more	more	JJR
cord-010027-r0tl01kq	399	22	pTEN	pten	JJ
cord-010027-r0tl01kq	399	23	negative	negative	JJ
cord-010027-r0tl01kq	399	24	tumours	tumour	NNS
cord-010027-r0tl01kq	399	25	having	have	VBG
cord-010027-r0tl01kq	399	26	the	the	DT
cord-010027-r0tl01kq	399	27	BRAF	BRAF	NNP
cord-010027-r0tl01kq	399	28	V600E	V600E	NNP
cord-010027-r0tl01kq	399	29	mutation	mutation	NN
cord-010027-r0tl01kq	399	30	.	.	.
cord-010027-r0tl01kq	400	1	Loss	loss	NN
cord-010027-r0tl01kq	400	2	of	of	IN
cord-010027-r0tl01kq	400	3	pTEN	pten	JJ
cord-010027-r0tl01kq	400	4	expression	expression	NN
cord-010027-r0tl01kq	400	5	correlated	correlate	VBN
cord-010027-r0tl01kq	400	6	with	with	IN
cord-010027-r0tl01kq	400	7	genomic	genomic	JJ
cord-010027-r0tl01kq	400	8	deletions	deletion	NNS
cord-010027-r0tl01kq	400	9	involving	involve	VBG
cord-010027-r0tl01kq	400	10	the	the	DT
cord-010027-r0tl01kq	400	11	pTEN	pten	NN
cord-010027-r0tl01kq	400	12	gene	gene	NN
cord-010027-r0tl01kq	400	13	.	.	.
cord-010027-r0tl01kq	401	1	20/30	20/30	CD
cord-010027-r0tl01kq	401	2	(	(	-LRB-
cord-010027-r0tl01kq	401	3	66	66	CD
cord-010027-r0tl01kq	401	4	%	%	NN
cord-010027-r0tl01kq	401	5	)	)	-RRB-
cord-010027-r0tl01kq	401	6	of	of	IN
cord-010027-r0tl01kq	401	7	pTEN	pten	JJ
cord-010027-r0tl01kq	401	8	negative	negative	JJ
cord-010027-r0tl01kq	401	9	tumours	tumour	NNS
cord-010027-r0tl01kq	401	10	exhibited	exhibit	VBD
cord-010027-r0tl01kq	401	11	loss	loss	NN
cord-010027-r0tl01kq	401	12	of	of	IN
cord-010027-r0tl01kq	401	13	the	the	DT
cord-010027-r0tl01kq	401	14	pTEN	pten	JJ
cord-010027-r0tl01kq	401	15	region	region	NN
cord-010027-r0tl01kq	401	16	(	(	-LRB-
cord-010027-r0tl01kq	401	17	10q	10q	CD
cord-010027-r0tl01kq	401	18	)	)	-RRB-
cord-010027-r0tl01kq	401	19	,	,	,
cord-010027-r0tl01kq	401	20	half	half	NN
cord-010027-r0tl01kq	401	21	of	of	IN
cord-010027-r0tl01kq	401	22	which	which	WDT
cord-010027-r0tl01kq	401	23	were	be	VBD
cord-010027-r0tl01kq	401	24	focal	focal	JJ
cord-010027-r0tl01kq	401	25	deletions	deletion	NNS
cord-010027-r0tl01kq	401	26	.	.	.
cord-010027-r0tl01kq	402	1	Only	only	RB
cord-010027-r0tl01kq	402	2	54/202	54/202	CD
cord-010027-r0tl01kq	402	3	(	(	-LRB-
cord-010027-r0tl01kq	402	4	26.7	26.7	CD
cord-010027-r0tl01kq	402	5	%	%	NN
cord-010027-r0tl01kq	402	6	)	)	-RRB-
cord-010027-r0tl01kq	403	1	pTEN	pten	JJ
cord-010027-r0tl01kq	403	2	positive	positive	JJ
cord-010027-r0tl01kq	403	3	tumours	tumour	NNS
cord-010027-r0tl01kq	403	4	showed	show	VBD
cord-010027-r0tl01kq	403	5	deletions	deletion	NNS
cord-010027-r0tl01kq	403	6	of	of	IN
cord-010027-r0tl01kq	403	7	this	this	DT
cord-010027-r0tl01kq	403	8	region	region	NN
cord-010027-r0tl01kq	403	9	,	,	,
cord-010027-r0tl01kq	403	10	and	and	CC
cord-010027-r0tl01kq	403	11	none	none	NN
cord-010027-r0tl01kq	403	12	were	be	VBD
cord-010027-r0tl01kq	403	13	focal	focal	JJ
cord-010027-r0tl01kq	403	14	events	event	NNS
cord-010027-r0tl01kq	403	15	.	.	.
cord-010027-r0tl01kq	404	1	There	there	EX
cord-010027-r0tl01kq	404	2	was	be	VBD
cord-010027-r0tl01kq	404	3	no	no	DT
cord-010027-r0tl01kq	404	4	significant	significant	JJ
cord-010027-r0tl01kq	404	5	difference	difference	NN
cord-010027-r0tl01kq	404	6	in	in	IN
cord-010027-r0tl01kq	404	7	either	either	DT
cord-010027-r0tl01kq	404	8	primary	primary	JJ
cord-010027-r0tl01kq	404	9	tumour	tumour	NN
cord-010027-r0tl01kq	404	10	site	site	NN
cord-010027-r0tl01kq	404	11	or	or	CC
cord-010027-r0tl01kq	404	12	MMR	MMR	NNP
cord-010027-r0tl01kq	404	13	status	status	NN
cord-010027-r0tl01kq	404	14	(	(	-LRB-
cord-010027-r0tl01kq	404	15	p=0.1765	p=0.1765	NNP
cord-010027-r0tl01kq	404	16	)	)	-RRB-
cord-010027-r0tl01kq	404	17	between	between	IN
cord-010027-r0tl01kq	404	18	the	the	DT
cord-010027-r0tl01kq	404	19	pTEN	pten	JJ
cord-010027-r0tl01kq	404	20	negative	negative	JJ
cord-010027-r0tl01kq	404	21	and	and	CC
cord-010027-r0tl01kq	404	22	pTEN	pten	JJ
cord-010027-r0tl01kq	404	23	positive	positive	JJ
cord-010027-r0tl01kq	404	24	populations	population	NNS
cord-010027-r0tl01kq	404	25	.	.	.
cord-010027-r0tl01kq	405	1	Signalling	signal	VBG
cord-010027-r0tl01kq	405	2	pathways	pathway	NNS
cord-010027-r0tl01kq	405	3	do	do	VBP
cord-010027-r0tl01kq	405	4	not	not	RB
cord-010027-r0tl01kq	405	5	stand	stand	VB
cord-010027-r0tl01kq	405	6	in	in	IN
cord-010027-r0tl01kq	405	7	isolation	isolation	NN
cord-010027-r0tl01kq	405	8	;	;	:
cord-010027-r0tl01kq	405	9	they	-PRON-	PRP
cord-010027-r0tl01kq	405	10	are	be	VBP
cord-010027-r0tl01kq	405	11	interlinked	interlink	VBN
cord-010027-r0tl01kq	405	12	in	in	IN
cord-010027-r0tl01kq	405	13	a	a	DT
cord-010027-r0tl01kq	405	14	complex	complex	JJ
cord-010027-r0tl01kq	405	15	signalling	signalling	NN
cord-010027-r0tl01kq	405	16	network	network	NN
cord-010027-r0tl01kq	405	17	.	.	.
cord-010027-r0tl01kq	406	1	Current	current	JJ
cord-010027-r0tl01kq	406	2	treatment	treatment	NN
cord-010027-r0tl01kq	406	3	interventions	intervention	NNS
cord-010027-r0tl01kq	406	4	must	must	MD
cord-010027-r0tl01kq	406	5	target	target	VB
cord-010027-r0tl01kq	406	6	the	the	DT
cord-010027-r0tl01kq	406	7	correct	correct	JJ
cord-010027-r0tl01kq	406	8	pathway	pathway	NN
cord-010027-r0tl01kq	406	9	combinations	combination	NNS
cord-010027-r0tl01kq	406	10	if	if	IN
cord-010027-r0tl01kq	406	11	patients	patient	NNS
cord-010027-r0tl01kq	406	12	are	be	VBP
cord-010027-r0tl01kq	406	13	to	to	TO
cord-010027-r0tl01kq	406	14	benefit	benefit	VB
cord-010027-r0tl01kq	406	15	from	from	IN
cord-010027-r0tl01kq	406	16	targeted	target	VBN
cord-010027-r0tl01kq	406	17	therapy	therapy	NN
cord-010027-r0tl01kq	406	18	.	.	.
cord-010027-r0tl01kq	407	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	407	2	data	data	NN
cord-010027-r0tl01kq	407	3	suggests	suggest	VBZ
cord-010027-r0tl01kq	407	4	a	a	DT
cord-010027-r0tl01kq	407	5	subset	subset	NN
cord-010027-r0tl01kq	407	6	of	of	IN
cord-010027-r0tl01kq	407	7	patients	patient	NNS
cord-010027-r0tl01kq	407	8	may	may	MD
cord-010027-r0tl01kq	407	9	require	require	VB
cord-010027-r0tl01kq	407	10	dual	dual	JJ
cord-010027-r0tl01kq	407	11	AKT	AKT	NNP
cord-010027-r0tl01kq	407	12	and	and	CC
cord-010027-r0tl01kq	407	13	MEK	MEK	NNP
cord-010027-r0tl01kq	407	14	pathway	pathway	NN
cord-010027-r0tl01kq	407	15	inhibition	inhibition	NN
cord-010027-r0tl01kq	407	16	,	,	,
cord-010027-r0tl01kq	407	17	in	in	IN
cord-010027-r0tl01kq	407	18	addition	addition	NN
cord-010027-r0tl01kq	407	19	to	to	IN
cord-010027-r0tl01kq	407	20	anti	anti	JJ
cord-010027-r0tl01kq	407	21	-	-	JJ
cord-010027-r0tl01kq	407	22	EGFR	egfr	JJ
cord-010027-r0tl01kq	407	23	monoclonal	monoclonal	JJ
cord-010027-r0tl01kq	407	24	antibody	antibody	NN
cord-010027-r0tl01kq	407	25	therapy	therapy	NN
cord-010027-r0tl01kq	407	26	and	and	CC
cord-010027-r0tl01kq	407	27	inhibition	inhibition	NN
cord-010027-r0tl01kq	407	28	of	of	IN
cord-010027-r0tl01kq	407	29	BRAF	BRAF	NNP
cord-010027-r0tl01kq	407	30	.	.	.
cord-010027-r0tl01kq	408	1	Zonal	Zonal	NNP
cord-010027-r0tl01kq	408	2	Differences	Differences	NNPS
cord-010027-r0tl01kq	408	3	in	in	IN
cord-010027-r0tl01kq	408	4	PD1	PD1	NNP
cord-010027-r0tl01kq	408	5	Expression	Expression	NNP
cord-010027-r0tl01kq	408	6	in	in	IN
cord-010027-r0tl01kq	408	7	Centre	Centre	NNP
cord-010027-r0tl01kq	408	8	of	of	IN
cord-010027-r0tl01kq	408	9	Tumour	Tumour	NNP
cord-010027-r0tl01kq	409	1	Versus	versus	IN
cord-010027-r0tl01kq	409	2	Periphery	Periphery	NNP
cord-010027-r0tl01kq	409	3	in	in	IN
cord-010027-r0tl01kq	409	4	Microsatellite	Microsatellite	NNP
cord-010027-r0tl01kq	409	5	Stable	stable	JJ
cord-010027-r0tl01kq	409	6	and	and	CC
cord-010027-r0tl01kq	409	7	Unstable	unstable	JJ
cord-010027-r0tl01kq	409	8	Colorectal	Colorectal	NNP
cord-010027-r0tl01kq	410	1	Cancer	cancer	NN
cord-010027-r0tl01kq	410	2	P	p	NN
cord-010027-r0tl01kq	410	3	GM	GM	NNP
cord-010027-r0tl01kq	410	4	O'Kane	O'Kane	NNP
cord-010027-r0tl01kq	410	5	1	1	CD
cord-010027-r0tl01kq	411	1	;	;	:
cord-010027-r0tl01kq	411	2	M	M	NNP
cord-010027-r0tl01kq	411	3	Lynch	Lynch	NNP
cord-010027-r0tl01kq	411	4	2	2	CD
cord-010027-r0tl01kq	411	5	;	;	:
cord-010027-r0tl01kq	411	6	J	J	NNP
cord-010027-r0tl01kq	411	7	Aird	Aird	NNP
cord-010027-r0tl01kq	411	8	3	3	CD
cord-010027-r0tl01kq	411	9	;	;	:
cord-010027-r0tl01kq	411	10	S	S	NNP
cord-010027-r0tl01kq	411	11	Hooper	Hooper	NNP
cord-010027-r0tl01kq	411	12	3	3	CD
cord-010027-r0tl01kq	411	13	;	;	:
cord-010027-r0tl01kq	411	14	C	C	NNP
cord-010027-r0tl01kq	411	15	Muldoon	Muldoon	NNP
cord-010027-r0tl01kq	411	16	1	1	CD
cord-010027-r0tl01kq	411	17	;	;	:
cord-010027-r0tl01kq	411	18	N	n	CD
cord-010027-r0tl01kq	411	19	Mulligan	Mulligan	NNP
cord-010027-r0tl01kq	411	20	3	3	CD
cord-010027-r0tl01kq	411	21	;	;	:
cord-010027-r0tl01kq	411	22	C	C	NNP
cord-010027-r0tl01kq	411	23	Loscher	Loscher	NNP
cord-010027-r0tl01kq	411	24	2	2	CD
cord-010027-r0tl01kq	411	25	;	;	:
cord-010027-r0tl01kq	412	1	DJ	DJ	NNP
cord-010027-r0tl01kq	412	2	Gallagher	Gallagher	NNP
cord-010027-r0tl01kq	412	3	3	3	CD
cord-010027-r0tl01kq	412	4	1	1	CD
cord-010027-r0tl01kq	412	5	St.	St.	NNP
cord-010027-r0tl01kq	412	6	James	James	NNP
cord-010027-r0tl01kq	412	7	's	's	POS
cord-010027-r0tl01kq	412	8	Hospital	Hospital	NNP
cord-010027-r0tl01kq	412	9	,	,	,
cord-010027-r0tl01kq	412	10	Dublin	Dublin	NNP
cord-010027-r0tl01kq	412	11	,	,	,
cord-010027-r0tl01kq	412	12	Ireland	Ireland	NNP
cord-010027-r0tl01kq	412	13	;	;	:
cord-010027-r0tl01kq	412	14	2	2	CD
cord-010027-r0tl01kq	412	15	Dublin	Dublin	NNP
cord-010027-r0tl01kq	412	16	City	City	NNP
cord-010027-r0tl01kq	412	17	University	University	NNP
cord-010027-r0tl01kq	412	18	,	,	,
cord-010027-r0tl01kq	412	19	Dublin	Dublin	NNP
cord-010027-r0tl01kq	412	20	,	,	,
cord-010027-r0tl01kq	412	21	Ireland	Ireland	NNP
cord-010027-r0tl01kq	412	22	;	;	:
cord-010027-r0tl01kq	412	23	3	3	CD
cord-010027-r0tl01kq	412	24	Mater	Mater	NNP
cord-010027-r0tl01kq	412	25	Misericordiae	Misericordiae	NNP
cord-010027-r0tl01kq	412	26	University	University	NNP
cord-010027-r0tl01kq	412	27	Hospital	Hospital	NNP
cord-010027-r0tl01kq	412	28	,	,	,
cord-010027-r0tl01kq	412	29	Dublin	Dublin	NNP
cord-010027-r0tl01kq	412	30	,	,	,
cord-010027-r0tl01kq	412	31	Ireland	Ireland	NNP
cord-010027-r0tl01kq	412	32	Colorectal	Colorectal	NNP
cord-010027-r0tl01kq	412	33	cancers	cancer	NNS
cord-010027-r0tl01kq	412	34	(	(	-LRB-
cord-010027-r0tl01kq	412	35	CRC	CRC	NNP
cord-010027-r0tl01kq	412	36	)	)	-RRB-
cord-010027-r0tl01kq	412	37	that	that	WDT
cord-010027-r0tl01kq	412	38	show	show	VBP
cord-010027-r0tl01kq	412	39	evidence	evidence	NN
cord-010027-r0tl01kq	412	40	of	of	IN
cord-010027-r0tl01kq	412	41	microsatellite	microsatellite	JJ
cord-010027-r0tl01kq	412	42	instability	instability	NN
cord-010027-r0tl01kq	413	1	(	(	-LRB-
cord-010027-r0tl01kq	413	2	MSI	MSI	NNP
cord-010027-r0tl01kq	413	3	-	-	HYPH
cord-010027-r0tl01kq	413	4	H	H	NNP
cord-010027-r0tl01kq	413	5	)	)	-RRB-
cord-010027-r0tl01kq	413	6	are	be	VBP
cord-010027-r0tl01kq	413	7	marked	mark	VBN
cord-010027-r0tl01kq	413	8	by	by	IN
cord-010027-r0tl01kq	413	9	a	a	DT
cord-010027-r0tl01kq	413	10	high	high	JJ
cord-010027-r0tl01kq	413	11	tumour	tumour	NN
cord-010027-r0tl01kq	413	12	infiltrating	infiltrate	VBG
cord-010027-r0tl01kq	413	13	lymphocyte	lymphocyte	NN
cord-010027-r0tl01kq	413	14	(	(	-LRB-
cord-010027-r0tl01kq	413	15	TiL	til	NN
cord-010027-r0tl01kq	413	16	)	)	-RRB-
cord-010027-r0tl01kq	413	17	population	population	NN
cord-010027-r0tl01kq	413	18	which	which	WDT
cord-010027-r0tl01kq	413	19	is	be	VBZ
cord-010027-r0tl01kq	413	20	thought	think	VBN
cord-010027-r0tl01kq	413	21	to	to	TO
cord-010027-r0tl01kq	413	22	be	be	VB
cord-010027-r0tl01kq	413	23	prognostic	prognostic	JJ
cord-010027-r0tl01kq	413	24	.	.	.
cord-010027-r0tl01kq	414	1	Programmed	program	VBN
cord-010027-r0tl01kq	414	2	cell	cell	NN
cord-010027-r0tl01kq	414	3	death	death	NN
cord-010027-r0tl01kq	414	4	1(PD-1	1(pd-1	CD
cord-010027-r0tl01kq	414	5	)	)	-RRB-
cord-010027-r0tl01kq	414	6	is	be	VBZ
cord-010027-r0tl01kq	414	7	a	a	DT
cord-010027-r0tl01kq	414	8	negative	negative	JJ
cord-010027-r0tl01kq	414	9	regulator	regulator	NN
cord-010027-r0tl01kq	414	10	of	of	IN
cord-010027-r0tl01kq	414	11	the	the	DT
cord-010027-r0tl01kq	414	12	immune	immune	JJ
cord-010027-r0tl01kq	414	13	system	system	NN
cord-010027-r0tl01kq	414	14	and	and	CC
cord-010027-r0tl01kq	414	15	targeting	target	VBG
cord-010027-r0tl01kq	414	16	the	the	DT
cord-010027-r0tl01kq	414	17	interaction	interaction	NN
cord-010027-r0tl01kq	414	18	with	with	IN
cord-010027-r0tl01kq	414	19	its	-PRON-	PRP$
cord-010027-r0tl01kq	414	20	ligand	ligand	NN
cord-010027-r0tl01kq	414	21	PD	PD	NNP
cord-010027-r0tl01kq	414	22	-	-	HYPH
cord-010027-r0tl01kq	414	23	L1	L1	NNP
cord-010027-r0tl01kq	414	24	offers	offer	VBZ
cord-010027-r0tl01kq	414	25	a	a	DT
cord-010027-r0tl01kq	414	26	potential	potential	JJ
cord-010027-r0tl01kq	414	27	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	414	28	target	target	NN
cord-010027-r0tl01kq	414	29	.	.	.
cord-010027-r0tl01kq	415	1	We	-PRON-	PRP
cord-010027-r0tl01kq	415	2	aimed	aim	VBD
cord-010027-r0tl01kq	415	3	to	to	TO
cord-010027-r0tl01kq	415	4	characterize	characterize	VB
cord-010027-r0tl01kq	415	5	CD8	CD8	NNP
cord-010027-r0tl01kq	415	6	and	and	CC
cord-010027-r0tl01kq	415	7	PD-1	PD-1	NNP
cord-010027-r0tl01kq	415	8	expression	expression	NN
cord-010027-r0tl01kq	415	9	in	in	IN
cord-010027-r0tl01kq	415	10	both	both	CC
cord-010027-r0tl01kq	415	11	the	the	DT
cord-010027-r0tl01kq	415	12	tumour	tumour	NN
cord-010027-r0tl01kq	415	13	centre	centre	NN
cord-010027-r0tl01kq	415	14	(	(	-LRB-
cord-010027-r0tl01kq	415	15	cT	ct	NN
cord-010027-r0tl01kq	415	16	)	)	-RRB-
cord-010027-r0tl01kq	415	17	and	and	CC
cord-010027-r0tl01kq	415	18	tumour	tumour	NN
cord-010027-r0tl01kq	415	19	periphery	periphery	NN
cord-010027-r0tl01kq	415	20	(	(	-LRB-
cord-010027-r0tl01kq	415	21	pT	pT	NNP
cord-010027-r0tl01kq	415	22	)	)	-RRB-
cord-010027-r0tl01kq	415	23	of	of	IN
cord-010027-r0tl01kq	415	24	microsatellite	microsatellite	JJ
cord-010027-r0tl01kq	415	25	stable	stable	JJ
cord-010027-r0tl01kq	415	26	(	(	-LRB-
cord-010027-r0tl01kq	415	27	MSS	MSS	NNP
cord-010027-r0tl01kq	415	28	)	)	-RRB-
cord-010027-r0tl01kq	415	29	and	and	CC
cord-010027-r0tl01kq	415	30	unstable	unstable	JJ
cord-010027-r0tl01kq	415	31	CRC	crc	NN
cord-010027-r0tl01kq	415	32	.	.	.
cord-010027-r0tl01kq	416	1	Methods	method	NNS
cord-010027-r0tl01kq	416	2	:	:	:
cord-010027-r0tl01kq	416	3	Paraffin	paraffin	NN
cord-010027-r0tl01kq	416	4	-	-	HYPH
cord-010027-r0tl01kq	416	5	embedded	embed	VBN
cord-010027-r0tl01kq	416	6	tumour	tumour	NN
cord-010027-r0tl01kq	416	7	blocks	block	NNS
cord-010027-r0tl01kq	416	8	were	be	VBD
cord-010027-r0tl01kq	416	9	cut	cut	VBN
cord-010027-r0tl01kq	416	10	at	at	IN
cord-010027-r0tl01kq	416	11	5um	5um	NN
cord-010027-r0tl01kq	416	12	,	,	,
cord-010027-r0tl01kq	416	13	prepared	prepared	JJ
cord-010027-r0tl01kq	416	14	and	and	CC
cord-010027-r0tl01kq	416	15	stained	stain	VBN
cord-010027-r0tl01kq	416	16	using	use	VBG
cord-010027-r0tl01kq	416	17	specific	specific	JJ
cord-010027-r0tl01kq	416	18	antibodies	antibody	NNS
cord-010027-r0tl01kq	416	19	for	for	IN
cord-010027-r0tl01kq	416	20	CD8	CD8	NNP
cord-010027-r0tl01kq	416	21	and	and	CC
cord-010027-r0tl01kq	416	22	PD-1	PD-1	NNP
cord-010027-r0tl01kq	416	23	.	.	.
cord-010027-r0tl01kq	417	1	The	the	DT
cord-010027-r0tl01kq	417	2	pT	pT	NNP
cord-010027-r0tl01kq	417	3	was	be	VBD
cord-010027-r0tl01kq	417	4	defined	define	VBN
cord-010027-r0tl01kq	417	5	as	as	IN
cord-010027-r0tl01kq	417	6	the	the	DT
cord-010027-r0tl01kq	417	7	area	area	NN
cord-010027-r0tl01kq	417	8	within	within	IN
cord-010027-r0tl01kq	417	9	a	a	DT
cord-010027-r0tl01kq	417	10	400x	400x	CD
cord-010027-r0tl01kq	417	11	high	high	JJ
cord-010027-r0tl01kq	417	12	power	power	NN
cord-010027-r0tl01kq	417	13	field	field	NN
cord-010027-r0tl01kq	417	14	(	(	-LRB-
cord-010027-r0tl01kq	417	15	HPF	HPF	NNP
cord-010027-r0tl01kq	417	16	)	)	-RRB-
cord-010027-r0tl01kq	417	17	from	from	IN
cord-010027-r0tl01kq	417	18	the	the	DT
cord-010027-r0tl01kq	417	19	outline	outline	NN
cord-010027-r0tl01kq	417	20	of	of	IN
cord-010027-r0tl01kq	417	21	the	the	DT
cord-010027-r0tl01kq	417	22	tumor	tumor	NN
cord-010027-r0tl01kq	417	23	.	.	.
cord-010027-r0tl01kq	418	1	The	the	DT
cord-010027-r0tl01kq	418	2	cT	ct	NN
cord-010027-r0tl01kq	418	3	was	be	VBD
cord-010027-r0tl01kq	418	4	defined	define	VBN
cord-010027-r0tl01kq	418	5	as	as	IN
cord-010027-r0tl01kq	418	6	the	the	DT
cord-010027-r0tl01kq	418	7	area	area	NN
cord-010027-r0tl01kq	418	8	at	at	IN
cord-010027-r0tl01kq	418	9	least	least	JJS
cord-010027-r0tl01kq	418	10	one	one	CD
cord-010027-r0tl01kq	418	11	400x	400x	CD
cord-010027-r0tl01kq	418	12	HPF	HPF	NNP
cord-010027-r0tl01kq	419	1	apart	apart	RB
cord-010027-r0tl01kq	419	2	from	from	IN
cord-010027-r0tl01kq	419	3	the	the	DT
cord-010027-r0tl01kq	419	4	tumor	tumor	NN
cord-010027-r0tl01kq	419	5	outline	outline	NN
cord-010027-r0tl01kq	419	6	toward	toward	IN
cord-010027-r0tl01kq	419	7	centre	centre	NN
cord-010027-r0tl01kq	419	8	of	of	IN
cord-010027-r0tl01kq	419	9	the	the	DT
cord-010027-r0tl01kq	419	10	tumor	tumor	NN
cord-010027-r0tl01kq	419	11	.	.	.
cord-010027-r0tl01kq	420	1	Images	image	NNS
cord-010027-r0tl01kq	420	2	were	be	VBD
cord-010027-r0tl01kq	420	3	taken	take	VBN
cord-010027-r0tl01kq	420	4	at	at	IN
cord-010027-r0tl01kq	420	5	40x	40x	CD
cord-010027-r0tl01kq	420	6	,	,	,
cord-010027-r0tl01kq	420	7	100x	100x	CD
cord-010027-r0tl01kq	420	8	,	,	,
cord-010027-r0tl01kq	420	9	200x	200x	CD
cord-010027-r0tl01kq	420	10	and	and	CC
cord-010027-r0tl01kq	420	11	400x	400x	CD
cord-010027-r0tl01kq	420	12	.	.	.
cord-010027-r0tl01kq	421	1	Positive	positive	JJ
cord-010027-r0tl01kq	421	2	cells	cell	NNS
cord-010027-r0tl01kq	421	3	were	be	VBD
cord-010027-r0tl01kq	421	4	averaged	average	VBN
cord-010027-r0tl01kq	421	5	across	across	IN
cord-010027-r0tl01kq	421	6	3	3	CD
cord-010027-r0tl01kq	421	7	high	high	JJ
cord-010027-r0tl01kq	421	8	power	power	NN
cord-010027-r0tl01kq	421	9	fields	field	NNS
cord-010027-r0tl01kq	421	10	and	and	CC
cord-010027-r0tl01kq	421	11	classified	classify	VBN
cord-010027-r0tl01kq	421	12	as	as	IN
cord-010027-r0tl01kq	421	13	high	high	JJ
cord-010027-r0tl01kq	421	14	or	or	CC
cord-010027-r0tl01kq	421	15	low	low	JJ
cord-010027-r0tl01kq	421	16	positivity	positivity	NN
cord-010027-r0tl01kq	421	17	.	.	.
cord-010027-r0tl01kq	422	1	Results	result	NNS
cord-010027-r0tl01kq	422	2	:	:	:
cord-010027-r0tl01kq	423	1	Forty	forty	CD
cord-010027-r0tl01kq	423	2	-	-	HYPH
cord-010027-r0tl01kq	423	3	two	two	CD
cord-010027-r0tl01kq	423	4	specimens	specimen	NNS
cord-010027-r0tl01kq	423	5	have	have	VBP
cord-010027-r0tl01kq	423	6	been	be	VBN
cord-010027-r0tl01kq	423	7	analysed	analyse	VBN
cord-010027-r0tl01kq	423	8	to	to	IN
cord-010027-r0tl01kq	423	9	date	date	NN
cord-010027-r0tl01kq	423	10	including	include	VBG
cord-010027-r0tl01kq	423	11	28	28	CD
cord-010027-r0tl01kq	423	12	MSI	MSI	NNP
cord-010027-r0tl01kq	423	13	-	-	HYPH
cord-010027-r0tl01kq	423	14	H	H	NNP
cord-010027-r0tl01kq	423	15	and	and	CC
cord-010027-r0tl01kq	423	16	13	13	CD
cord-010027-r0tl01kq	423	17	MSS	MSS	NNP
cord-010027-r0tl01kq	423	18	tumours	tumour	NNS
cord-010027-r0tl01kq	423	19	.	.	.
cord-010027-r0tl01kq	424	1	Sixty	sixty	CD
cord-010027-r0tl01kq	424	2	-	-	HYPH
cord-010027-r0tl01kq	424	3	eight	eight	CD
cord-010027-r0tl01kq	424	4	percent	percent	NN
cord-010027-r0tl01kq	424	5	of	of	IN
cord-010027-r0tl01kq	424	6	MSI	MSI	NNP
cord-010027-r0tl01kq	424	7	-	-	HYPH
cord-010027-r0tl01kq	424	8	H	H	NNP
cord-010027-r0tl01kq	424	9	were	be	VBD
cord-010027-r0tl01kq	424	10	stage	stage	NN
cord-010027-r0tl01kq	424	11	II	II	NNP
cord-010027-r0tl01kq	424	12	and	and	CC
cord-010027-r0tl01kq	425	1	69	69	CD
cord-010027-r0tl01kq	425	2	%	%	NN
cord-010027-r0tl01kq	425	3	of	of	IN
cord-010027-r0tl01kq	425	4	MSS	MSS	NNP
cord-010027-r0tl01kq	425	5	were	be	VBD
cord-010027-r0tl01kq	425	6	stage	stage	NN
cord-010027-r0tl01kq	425	7	III	III	NNP
cord-010027-r0tl01kq	425	8	.	.	.
cord-010027-r0tl01kq	426	1	In	in	IN
cord-010027-r0tl01kq	426	2	the	the	DT
cord-010027-r0tl01kq	426	3	MSI	MSI	NNP
cord-010027-r0tl01kq	426	4	-	-	HYPH
cord-010027-r0tl01kq	426	5	H	H	NNP
cord-010027-r0tl01kq	426	6	group	group	NN
cord-010027-r0tl01kq	426	7	,	,	,
cord-010027-r0tl01kq	426	8	a	a	DT
cord-010027-r0tl01kq	426	9	high	high	JJ
cord-010027-r0tl01kq	426	10	CD8	CD8	NNP
cord-010027-r0tl01kq	426	11	count	count	VBP
cord-010027-r0tl01kq	426	12	in	in	IN
cord-010027-r0tl01kq	426	13	the	the	DT
cord-010027-r0tl01kq	426	14	cT	cT	NNP
cord-010027-r0tl01kq	426	15	and	and	CC
cord-010027-r0tl01kq	426	16	pT	pT	NNP
cord-010027-r0tl01kq	426	17	correlated	correlate	VBN
cord-010027-r0tl01kq	426	18	with	with	IN
cord-010027-r0tl01kq	426	19	and	and	CC
cord-010027-r0tl01kq	426	20	earlier	early	JJR
cord-010027-r0tl01kq	426	21	tumour	tumour	NN
cord-010027-r0tl01kq	426	22	size	size	NN
cord-010027-r0tl01kq	426	23	and	and	CC
cord-010027-r0tl01kq	426	24	stage	stage	NN
cord-010027-r0tl01kq	426	25	.	.	.
cord-010027-r0tl01kq	427	1	PD-1	pd-1	DT
cord-010027-r0tl01kq	427	2	positivity	positivity	NN
cord-010027-r0tl01kq	427	3	was	be	VBD
cord-010027-r0tl01kq	427	4	seen	see	VBN
cord-010027-r0tl01kq	427	5	in	in	IN
cord-010027-r0tl01kq	427	6	61	61	CD
cord-010027-r0tl01kq	427	7	%	%	NN
cord-010027-r0tl01kq	427	8	of	of	IN
cord-010027-r0tl01kq	427	9	MSI	MSI	NNP
cord-010027-r0tl01kq	427	10	-	-	HYPH
cord-010027-r0tl01kq	427	11	H	H	NNP
cord-010027-r0tl01kq	427	12	cT	ct	NN
cord-010027-r0tl01kq	427	13	compared	compare	VBN
cord-010027-r0tl01kq	427	14	to	to	IN
cord-010027-r0tl01kq	427	15	0	0	CD
cord-010027-r0tl01kq	427	16	%	%	NN
cord-010027-r0tl01kq	427	17	positivity	positivity	NN
cord-010027-r0tl01kq	427	18	in	in	IN
cord-010027-r0tl01kq	427	19	the	the	DT
cord-010027-r0tl01kq	427	20	cT	ct	NN
cord-010027-r0tl01kq	427	21	of	of	IN
cord-010027-r0tl01kq	427	22	MSS	MSS	NNP
cord-010027-r0tl01kq	427	23	tumours	tumour	NNS
cord-010027-r0tl01kq	427	24	.	.	.
cord-010027-r0tl01kq	428	1	The	the	DT
cord-010027-r0tl01kq	428	2	periphery	periphery	NN
cord-010027-r0tl01kq	428	3	of	of	IN
cord-010027-r0tl01kq	428	4	both	both	DT
cord-010027-r0tl01kq	428	5	MSS	MSS	NNP
cord-010027-r0tl01kq	428	6	and	and	CC
cord-010027-r0tl01kq	428	7	MSI	MSI	NNP
cord-010027-r0tl01kq	428	8	-	-	HYPH
cord-010027-r0tl01kq	428	9	H	H	NNP
cord-010027-r0tl01kq	428	10	specimens	specimen	NNS
cord-010027-r0tl01kq	428	11	showed	show	VBD
cord-010027-r0tl01kq	428	12	significant	significant	JJ
cord-010027-r0tl01kq	428	13	PD-1	PD-1	NNP
cord-010027-r0tl01kq	428	14	expression	expression	NN
cord-010027-r0tl01kq	428	15	with	with	IN
cord-010027-r0tl01kq	428	16	71	71	CD
cord-010027-r0tl01kq	428	17	%	%	NN
cord-010027-r0tl01kq	428	18	and	and	CC
cord-010027-r0tl01kq	428	19	85	85	CD
cord-010027-r0tl01kq	428	20	%	%	NN
cord-010027-r0tl01kq	428	21	of	of	IN
cord-010027-r0tl01kq	428	22	samples	sample	NNS
cord-010027-r0tl01kq	428	23	showing	show	VBG
cord-010027-r0tl01kq	428	24	positivity	positivity	NN
cord-010027-r0tl01kq	428	25	respectively	respectively	RB
cord-010027-r0tl01kq	428	26	.	.	.
cord-010027-r0tl01kq	429	1	There	there	EX
cord-010027-r0tl01kq	429	2	was	be	VBD
cord-010027-r0tl01kq	429	3	no	no	DT
cord-010027-r0tl01kq	429	4	association	association	NN
cord-010027-r0tl01kq	429	5	between	between	IN
cord-010027-r0tl01kq	429	6	high	high	JJ
cord-010027-r0tl01kq	429	7	or	or	CC
cord-010027-r0tl01kq	429	8	low	low	JJ
cord-010027-r0tl01kq	429	9	densities	density	NNS
cord-010027-r0tl01kq	429	10	of	of	IN
cord-010027-r0tl01kq	429	11	staining	staining	NN
cord-010027-r0tl01kq	429	12	and	and	CC
cord-010027-r0tl01kq	429	13	stage	stage	NN
cord-010027-r0tl01kq	429	14	.	.	.
cord-010027-r0tl01kq	430	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	430	2	:	:	:
cord-010027-r0tl01kq	431	1	Zonal	zonal	JJ
cord-010027-r0tl01kq	431	2	differences	difference	NNS
cord-010027-r0tl01kq	431	3	exist	exist	VBP
cord-010027-r0tl01kq	431	4	in	in	IN
cord-010027-r0tl01kq	431	5	the	the	DT
cord-010027-r0tl01kq	431	6	expression	expression	NN
cord-010027-r0tl01kq	431	7	of	of	IN
cord-010027-r0tl01kq	431	8	CD8	CD8	NNP
cord-010027-r0tl01kq	431	9	and	and	CC
cord-010027-r0tl01kq	431	10	PD-1	PD-1	NNP
cord-010027-r0tl01kq	431	11	in	in	IN
cord-010027-r0tl01kq	431	12	microsatellite	microsatellite	JJ
cord-010027-r0tl01kq	431	13	stable	stable	JJ
cord-010027-r0tl01kq	431	14	and	and	CC
cord-010027-r0tl01kq	431	15	unstable	unstable	JJ
cord-010027-r0tl01kq	431	16	tumours	tumour	NNS
cord-010027-r0tl01kq	431	17	.	.	.
cord-010027-r0tl01kq	432	1	A	a	DT
cord-010027-r0tl01kq	432	2	high	high	JJ
cord-010027-r0tl01kq	432	3	proportion	proportion	NN
cord-010027-r0tl01kq	432	4	of	of	IN
cord-010027-r0tl01kq	432	5	MSI	MSI	NNP
cord-010027-r0tl01kq	432	6	-	-	HYPH
cord-010027-r0tl01kq	432	7	H	H	NNP
cord-010027-r0tl01kq	432	8	tumours	tumour	NNS
cord-010027-r0tl01kq	432	9	show	show	VBP
cord-010027-r0tl01kq	432	10	PD-1	PD-1	NNP
cord-010027-r0tl01kq	432	11	activity	activity	NN
cord-010027-r0tl01kq	432	12	in	in	IN
cord-010027-r0tl01kq	432	13	the	the	DT
cord-010027-r0tl01kq	432	14	centre	centre	NN
cord-010027-r0tl01kq	432	15	of	of	IN
cord-010027-r0tl01kq	432	16	the	the	DT
cord-010027-r0tl01kq	432	17	tumour	tumour	NN
cord-010027-r0tl01kq	432	18	despite	despite	IN
cord-010027-r0tl01kq	432	19	an	an	DT
cord-010027-r0tl01kq	432	20	improved	improved	JJ
cord-010027-r0tl01kq	432	21	prognosis	prognosis	NN
cord-010027-r0tl01kq	432	22	.	.	.
cord-010027-r0tl01kq	433	1	Further	further	JJ
cord-010027-r0tl01kq	433	2	profiling	profiling	NN
cord-010027-r0tl01kq	433	3	of	of	IN
cord-010027-r0tl01kq	433	4	other	other	JJ
cord-010027-r0tl01kq	433	5	T	t	NN
cord-010027-r0tl01kq	433	6	cell	cell	NN
cord-010027-r0tl01kq	433	7	populations	population	NNS
cord-010027-r0tl01kq	433	8	may	may	MD
cord-010027-r0tl01kq	433	9	help	help	VB
cord-010027-r0tl01kq	433	10	to	to	TO
cord-010027-r0tl01kq	433	11	further	further	RB
cord-010027-r0tl01kq	433	12	understand	understand	VB
cord-010027-r0tl01kq	433	13	this	this	DT
cord-010027-r0tl01kq	433	14	expression	expression	NN
cord-010027-r0tl01kq	433	15	which	which	WDT
cord-010027-r0tl01kq	433	16	may	may	MD
cord-010027-r0tl01kq	433	17	act	act	VB
cord-010027-r0tl01kq	433	18	as	as	IN
cord-010027-r0tl01kq	433	19	a	a	DT
cord-010027-r0tl01kq	433	20	biomarker	biomarker	NN
cord-010027-r0tl01kq	433	21	or	or	CC
cord-010027-r0tl01kq	433	22	provide	provide	VB
cord-010027-r0tl01kq	433	23	a	a	DT
cord-010027-r0tl01kq	433	24	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	433	25	target	target	NN
cord-010027-r0tl01kq	433	26	Biomarkers	biomarker	NNS
cord-010027-r0tl01kq	433	27	that	that	WDT
cord-010027-r0tl01kq	433	28	are	be	VBP
cord-010027-r0tl01kq	433	29	able	able	JJ
cord-010027-r0tl01kq	433	30	to	to	TO
cord-010027-r0tl01kq	433	31	distinguish	distinguish	VB
cord-010027-r0tl01kq	433	32	stage	stage	NN
cord-010027-r0tl01kq	433	33	II	II	NNP
cord-010027-r0tl01kq	433	34	and	and	CC
cord-010027-r0tl01kq	433	35	III	iii	CD
cord-010027-r0tl01kq	433	36	colon	colon	NN
cord-010027-r0tl01kq	433	37	cancer	cancer	NN
cord-010027-r0tl01kq	433	38	patients	patient	NNS
cord-010027-r0tl01kq	433	39	at	at	IN
cord-010027-r0tl01kq	433	40	high	high	JJ
cord-010027-r0tl01kq	433	41	risk	risk	NN
cord-010027-r0tl01kq	433	42	of	of	IN
cord-010027-r0tl01kq	433	43	developing	develop	VBG
cord-010027-r0tl01kq	433	44	disease	disease	NN
cord-010027-r0tl01kq	433	45	recurrence	recurrence	NN
cord-010027-r0tl01kq	433	46	,	,	,
cord-010027-r0tl01kq	433	47	who	who	WP
cord-010027-r0tl01kq	433	48	may	may	MD
cord-010027-r0tl01kq	433	49	benefit	benefit	VB
cord-010027-r0tl01kq	433	50	from	from	IN
cord-010027-r0tl01kq	433	51	adjuvant	adjuvant	JJ
cord-010027-r0tl01kq	433	52	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	433	53	,	,	,
cord-010027-r0tl01kq	433	54	are	be	VBP
cord-010027-r0tl01kq	433	55	still	still	RB
cord-010027-r0tl01kq	433	56	lacking	lack	VBG
cord-010027-r0tl01kq	433	57	.	.	.
cord-010027-r0tl01kq	434	1	Genome	genome	NN
cord-010027-r0tl01kq	434	2	-	-	HYPH
cord-010027-r0tl01kq	434	3	wide	wide	JJ
cord-010027-r0tl01kq	434	4	profiling	profiling	NN
cord-010027-r0tl01kq	434	5	of	of	IN
cord-010027-r0tl01kq	434	6	somatic	somatic	JJ
cord-010027-r0tl01kq	434	7	aberrations	aberration	NNS
cord-010027-r0tl01kq	434	8	,	,	,
cord-010027-r0tl01kq	434	9	including	include	VBG
cord-010027-r0tl01kq	434	10	gene	gene	NN
cord-010027-r0tl01kq	434	11	point	point	NN
cord-010027-r0tl01kq	434	12	mutations	mutation	NNS
cord-010027-r0tl01kq	434	13	,	,	,
cord-010027-r0tl01kq	434	14	DNA	DNA	NNP
cord-010027-r0tl01kq	434	15	copy	copy	NN
cord-010027-r0tl01kq	434	16	number	number	NN
cord-010027-r0tl01kq	434	17	aberrations	aberration	NNS
cord-010027-r0tl01kq	434	18	(	(	-LRB-
cord-010027-r0tl01kq	434	19	CNA	CNA	NNP
cord-010027-r0tl01kq	434	20	)	)	-RRB-
cord-010027-r0tl01kq	434	21	and	and	CC
cord-010027-r0tl01kq	434	22	structural	structural	JJ
cord-010027-r0tl01kq	434	23	variants	variant	NNS
cord-010027-r0tl01kq	434	24	(	(	-LRB-
cord-010027-r0tl01kq	434	25	SV	SV	NNP
cord-010027-r0tl01kq	434	26	)	)	-RRB-
cord-010027-r0tl01kq	434	27	,	,	,
cord-010027-r0tl01kq	434	28	is	be	VBZ
cord-010027-r0tl01kq	434	29	expected	expect	VBN
cord-010027-r0tl01kq	434	30	to	to	TO
cord-010027-r0tl01kq	434	31	provide	provide	VB
cord-010027-r0tl01kq	434	32	better	well	JJR
cord-010027-r0tl01kq	434	33	insight	insight	NN
cord-010027-r0tl01kq	434	34	into	into	IN
cord-010027-r0tl01kq	434	35	the	the	DT
cord-010027-r0tl01kq	434	36	molecular	molecular	JJ
cord-010027-r0tl01kq	434	37	pathology	pathology	NN
cord-010027-r0tl01kq	434	38	of	of	IN
cord-010027-r0tl01kq	434	39	tumour	tumour	NN
cord-010027-r0tl01kq	434	40	progression	progression	NN
cord-010027-r0tl01kq	434	41	and	and	CC
cord-010027-r0tl01kq	434	42	clinical	clinical	JJ
cord-010027-r0tl01kq	434	43	outcome	outcome	NN
cord-010027-r0tl01kq	434	44	.	.	.
cord-010027-r0tl01kq	435	1	Genome	genome	NN
cord-010027-r0tl01kq	435	2	-	-	HYPH
cord-010027-r0tl01kq	435	3	wide	wide	JJ
cord-010027-r0tl01kq	435	4	analysis	analysis	NN
cord-010027-r0tl01kq	435	5	of	of	IN
cord-010027-r0tl01kq	435	6	CNAs	CNAs	NNPS
cord-010027-r0tl01kq	435	7	was	be	VBD
cord-010027-r0tl01kq	435	8	performed	perform	VBN
cord-010027-r0tl01kq	435	9	using	use	VBG
cord-010027-r0tl01kq	435	10	high	high	JJ
cord-010027-r0tl01kq	435	11	-	-	HYPH
cord-010027-r0tl01kq	435	12	resolution	resolution	NN
cord-010027-r0tl01kq	435	13	comparative	comparative	JJ
cord-010027-r0tl01kq	435	14	genomic	genomic	JJ
cord-010027-r0tl01kq	435	15	hybridization	hybridization	NN
cord-010027-r0tl01kq	435	16	for	for	IN
cord-010027-r0tl01kq	435	17	microsatellite	microsatellite	JJ
cord-010027-r0tl01kq	435	18	stable	stable	JJ
cord-010027-r0tl01kq	435	19	(	(	-LRB-
cord-010027-r0tl01kq	435	20	MSS	MSS	NNP
cord-010027-r0tl01kq	435	21	)	)	-RRB-
cord-010027-r0tl01kq	435	22	stage	stage	NN
cord-010027-r0tl01kq	435	23	II	II	NNP
cord-010027-r0tl01kq	435	24	and	and	CC
cord-010027-r0tl01kq	435	25	III	iii	CD
cord-010027-r0tl01kq	435	26	primary	primary	JJ
cord-010027-r0tl01kq	435	27	colon	colon	NN
cord-010027-r0tl01kq	435	28	cancer	cancer	NN
cord-010027-r0tl01kq	435	29	samples	sample	NNS
cord-010027-r0tl01kq	435	30	(	(	-LRB-
cord-010027-r0tl01kq	435	31	n=114	n=114	NNP
cord-010027-r0tl01kq	435	32	)	)	-RRB-
cord-010027-r0tl01kq	435	33	.	.	.
cord-010027-r0tl01kq	436	1	In	in	IN
cord-010027-r0tl01kq	436	2	addition	addition	NN
cord-010027-r0tl01kq	436	3	,	,	,
cord-010027-r0tl01kq	436	4	the	the	DT
cord-010027-r0tl01kq	436	5	prevalence	prevalence	NN
cord-010027-r0tl01kq	436	6	of	of	IN
cord-010027-r0tl01kq	436	7	genes	gene	NNS
cord-010027-r0tl01kq	436	8	suffering	suffer	VBG
cord-010027-r0tl01kq	436	9	from	from	IN
cord-010027-r0tl01kq	436	10	CNA	CNA	NNP
cord-010027-r0tl01kq	436	11	-	-	HYPH
cord-010027-r0tl01kq	436	12	associated	associate	VBN
cord-010027-r0tl01kq	436	13	chromosomal	chromosomal	JJ
cord-010027-r0tl01kq	436	14	breaks	break	NNS
cord-010027-r0tl01kq	436	15	,	,	,
cord-010027-r0tl01kq	436	16	indicative	indicative	JJ
cord-010027-r0tl01kq	436	17	for	for	IN
cord-010027-r0tl01kq	436	18	SVs	sv	NNS
cord-010027-r0tl01kq	436	19	,	,	,
cord-010027-r0tl01kq	436	20	was	be	VBD
cord-010027-r0tl01kq	436	21	determined	determine	VBN
cord-010027-r0tl01kq	436	22	.	.	.
cord-010027-r0tl01kq	437	1	The	the	DT
cord-010027-r0tl01kq	437	2	mutation	mutation	NN
cord-010027-r0tl01kq	437	3	status	status	NN
cord-010027-r0tl01kq	437	4	of	of	IN
cord-010027-r0tl01kq	437	5	commonly	commonly	RB
cord-010027-r0tl01kq	437	6	affected	affect	VBN
cord-010027-r0tl01kq	437	7	APC	APC	NNP
cord-010027-r0tl01kq	437	8	,	,	,
cord-010027-r0tl01kq	437	9	TP53	TP53	NNP
cord-010027-r0tl01kq	437	10	,	,	,
cord-010027-r0tl01kq	437	11	KRAS	KRAS	NNP
cord-010027-r0tl01kq	437	12	,	,	,
cord-010027-r0tl01kq	437	13	PIK3CA	pik3ca	NN
cord-010027-r0tl01kq	437	14	,	,	,
cord-010027-r0tl01kq	437	15	FBXW7	fbxw7	CD
cord-010027-r0tl01kq	437	16	,	,	,
cord-010027-r0tl01kq	437	17	SMAD4	smad4	NN
cord-010027-r0tl01kq	437	18	,	,	,
cord-010027-r0tl01kq	437	19	BRAF	BRAF	NNP
cord-010027-r0tl01kq	437	20	and	and	CC
cord-010027-r0tl01kq	437	21	NRAS	NRAS	NNP
cord-010027-r0tl01kq	437	22	genes	gene	NNS
cord-010027-r0tl01kq	437	23	was	be	VBD
cord-010027-r0tl01kq	437	24	examined	examine	VBN
cord-010027-r0tl01kq	437	25	for	for	IN
cord-010027-r0tl01kq	437	26	60	60	CD
cord-010027-r0tl01kq	437	27	samples	sample	NNS
cord-010027-r0tl01kq	437	28	using	use	VBG
cord-010027-r0tl01kq	437	29	targeted	target	VBN
cord-010027-r0tl01kq	437	30	massive	massive	JJ
cord-010027-r0tl01kq	437	31	parallel	parallel	JJ
cord-010027-r0tl01kq	437	32	sequencing	sequencing	NN
cord-010027-r0tl01kq	437	33	.	.	.
cord-010027-r0tl01kq	438	1	Associations	association	NNS
cord-010027-r0tl01kq	438	2	of	of	IN
cord-010027-r0tl01kq	438	3	genomic	genomic	JJ
cord-010027-r0tl01kq	438	4	aberrations	aberration	NNS
cord-010027-r0tl01kq	438	5	with	with	IN
cord-010027-r0tl01kq	438	6	disease	disease	NN
cord-010027-r0tl01kq	438	7	-	-	HYPH
cord-010027-r0tl01kq	438	8	free	free	JJ
cord-010027-r0tl01kq	438	9	survival	survival	NN
cord-010027-r0tl01kq	438	10	(	(	-LRB-
cord-010027-r0tl01kq	438	11	DFS	DFS	NNP
cord-010027-r0tl01kq	438	12	)	)	-RRB-
cord-010027-r0tl01kq	438	13	rates	rate	NNS
cord-010027-r0tl01kq	438	14	were	be	VBD
cord-010027-r0tl01kq	438	15	explored	explore	VBN
cord-010027-r0tl01kq	438	16	by	by	IN
cord-010027-r0tl01kq	438	17	log	log	NN
cord-010027-r0tl01kq	438	18	-	-	HYPH
cord-010027-r0tl01kq	438	19	rank	rank	NN
cord-010027-r0tl01kq	438	20	tests	test	NNS
cord-010027-r0tl01kq	438	21	using	use	VBG
cord-010027-r0tl01kq	438	22	10,000	10,000	CD
cord-010027-r0tl01kq	438	23	permutations	permutation	NNS
cord-010027-r0tl01kq	438	24	.	.	.
cord-010027-r0tl01kq	439	1	Disease	disease	NN
cord-010027-r0tl01kq	439	2	recurrence	recurrence	NN
cord-010027-r0tl01kq	439	3	and	and	CC
cord-010027-r0tl01kq	439	4	DFS	DFS	NNP
cord-010027-r0tl01kq	439	5	rates	rate	NNS
cord-010027-r0tl01kq	439	6	differed	differ	VBD
cord-010027-r0tl01kq	439	7	significantly	significantly	RB
cord-010027-r0tl01kq	439	8	for	for	IN
cord-010027-r0tl01kq	439	9	several	several	JJ
cord-010027-r0tl01kq	439	10	CNA	CNA	NNP
cord-010027-r0tl01kq	439	11	-	-	HYPH
cord-010027-r0tl01kq	439	12	regions	region	NNS
cord-010027-r0tl01kq	439	13	(	(	-LRB-
cord-010027-r0tl01kq	439	14	P<0.05	P<0.05	NNS
cord-010027-r0tl01kq	439	15	)	)	-RRB-
cord-010027-r0tl01kq	439	16	.	.	.
cord-010027-r0tl01kq	440	1	A	a	DT
cord-010027-r0tl01kq	440	2	total	total	NN
cord-010027-r0tl01kq	440	3	of	of	IN
cord-010027-r0tl01kq	440	4	267	267	CD
cord-010027-r0tl01kq	440	5	genes	gene	NNS
cord-010027-r0tl01kq	440	6	were	be	VBD
cord-010027-r0tl01kq	440	7	recurrently	recurrently	RB
cord-010027-r0tl01kq	440	8	affected	affect	VBN
cord-010027-r0tl01kq	440	9	by	by	IN
cord-010027-r0tl01kq	440	10	CNA	CNA	NNP
cord-010027-r0tl01kq	440	11	-	-	HYPH
cord-010027-r0tl01kq	440	12	associated	associate	VBN
cord-010027-r0tl01kq	440	13	chromosomal	chromosomal	NN
cord-010027-r0tl01kq	440	14	breaks	break	NNS
cord-010027-r0tl01kq	440	15	(	(	-LRB-
cord-010027-r0tl01kq	440	16	FDR<0.1	FDR<0.1	NNP
cord-010027-r0tl01kq	440	17	)	)	-RRB-
cord-010027-r0tl01kq	440	18	,	,	,
cord-010027-r0tl01kq	440	19	among	among	IN
cord-010027-r0tl01kq	440	20	which	which	WDT
cord-010027-r0tl01kq	440	21	168	168	CD
cord-010027-r0tl01kq	440	22	genes	gene	NNS
cord-010027-r0tl01kq	440	23	(	(	-LRB-
cord-010027-r0tl01kq	440	24	66	66	CD
cord-010027-r0tl01kq	440	25	%	%	NN
cord-010027-r0tl01kq	440	26	)	)	-RRB-
cord-010027-r0tl01kq	440	27	that	that	WDT
cord-010027-r0tl01kq	440	28	were	be	VBD
cord-010027-r0tl01kq	440	29	also	also	RB
cord-010027-r0tl01kq	440	30	identified	identify	VBN
cord-010027-r0tl01kq	440	31	in	in	IN
cord-010027-r0tl01kq	440	32	a	a	DT
cord-010027-r0tl01kq	440	33	previously	previously	RB
cord-010027-r0tl01kq	440	34	analysed	analyse	VBN
cord-010027-r0tl01kq	440	35	cohort	cohort	NN
cord-010027-r0tl01kq	440	36	of	of	IN
cord-010027-r0tl01kq	440	37	352	352	CD
cord-010027-r0tl01kq	440	38	metastatic	metastatic	JJ
cord-010027-r0tl01kq	440	39	colorectal	colorectal	JJ
cord-010027-r0tl01kq	440	40	cancers	cancer	NNS
cord-010027-r0tl01kq	440	41	.	.	.
cord-010027-r0tl01kq	441	1	Gene	gene	NN
cord-010027-r0tl01kq	441	2	point	point	NN
cord-010027-r0tl01kq	441	3	mutation	mutation	NN
cord-010027-r0tl01kq	441	4	frequencies	frequency	NNS
cord-010027-r0tl01kq	441	5	were	be	VBD
cord-010027-r0tl01kq	441	6	in	in	IN
cord-010027-r0tl01kq	441	7	concordance	concordance	NN
cord-010027-r0tl01kq	441	8	with	with	IN
cord-010027-r0tl01kq	441	9	literature	literature	NN
cord-010027-r0tl01kq	441	10	.	.	.
cord-010027-r0tl01kq	442	1	In	in	IN
cord-010027-r0tl01kq	442	2	a	a	DT
cord-010027-r0tl01kq	442	3	univariate	univariate	JJ
cord-010027-r0tl01kq	442	4	analysis	analysis	NN
cord-010027-r0tl01kq	442	5	,	,	,
cord-010027-r0tl01kq	442	6	none	none	NN
cord-010027-r0tl01kq	442	7	of	of	IN
cord-010027-r0tl01kq	442	8	the	the	DT
cord-010027-r0tl01kq	442	9	individual	individual	JJ
cord-010027-r0tl01kq	442	10	mutated	mutate	VBN
cord-010027-r0tl01kq	442	11	genes	gene	NNS
cord-010027-r0tl01kq	442	12	appeared	appear	VBD
cord-010027-r0tl01kq	442	13	to	to	TO
cord-010027-r0tl01kq	442	14	be	be	VB
cord-010027-r0tl01kq	442	15	significantly	significantly	RB
cord-010027-r0tl01kq	442	16	associated	associate	VBN
cord-010027-r0tl01kq	442	17	with	with	IN
cord-010027-r0tl01kq	442	18	DFS	DFS	NNP
cord-010027-r0tl01kq	442	19	.	.	.
cord-010027-r0tl01kq	443	1	In	in	IN
cord-010027-r0tl01kq	443	2	summary	summary	NN
cord-010027-r0tl01kq	443	3	,	,	,
cord-010027-r0tl01kq	443	4	several	several	JJ
cord-010027-r0tl01kq	443	5	associations	association	NNS
cord-010027-r0tl01kq	443	6	are	be	VBP
cord-010027-r0tl01kq	443	7	found	find	VBN
cord-010027-r0tl01kq	443	8	between	between	IN
cord-010027-r0tl01kq	443	9	highly	highly	RB
cord-010027-r0tl01kq	443	10	prevalent	prevalent	JJ
cord-010027-r0tl01kq	443	11	genomic	genomic	JJ
cord-010027-r0tl01kq	443	12	CNAs	cna	NNS
cord-010027-r0tl01kq	443	13	and	and	CC
cord-010027-r0tl01kq	443	14	disease	disease	NN
cord-010027-r0tl01kq	443	15	recurrence	recurrence	NN
cord-010027-r0tl01kq	443	16	in	in	IN
cord-010027-r0tl01kq	443	17	this	this	DT
cord-010027-r0tl01kq	443	18	cohort	cohort	NN
cord-010027-r0tl01kq	443	19	of	of	IN
cord-010027-r0tl01kq	443	20	MSS	MSS	NNP
cord-010027-r0tl01kq	443	21	stage	stage	NN
cord-010027-r0tl01kq	443	22	II	II	NNP
cord-010027-r0tl01kq	443	23	and	and	CC
cord-010027-r0tl01kq	443	24	III	iii	CD
cord-010027-r0tl01kq	443	25	colon	colon	NN
cord-010027-r0tl01kq	443	26	cancers	cancer	NNS
cord-010027-r0tl01kq	443	27	.	.	.
cord-010027-r0tl01kq	444	1	Further	further	RB
cord-010027-r0tl01kq	444	2	in	in	IN
cord-010027-r0tl01kq	444	3	-	-	HYPH
cord-010027-r0tl01kq	444	4	depth	depth	NN
cord-010027-r0tl01kq	444	5	analysis	analysis	NN
cord-010027-r0tl01kq	444	6	is	be	VBZ
cord-010027-r0tl01kq	444	7	required	require	VBN
cord-010027-r0tl01kq	444	8	to	to	TO
cord-010027-r0tl01kq	444	9	unravel	unravel	VB
cord-010027-r0tl01kq	444	10	underlying	underlie	VBG
cord-010027-r0tl01kq	444	11	biology	biology	NN
cord-010027-r0tl01kq	444	12	that	that	WDT
cord-010027-r0tl01kq	444	13	contributes	contribute	VBZ
cord-010027-r0tl01kq	444	14	to	to	IN
cord-010027-r0tl01kq	444	15	disease	disease	NN
cord-010027-r0tl01kq	444	16	recurrence	recurrence	NN
cord-010027-r0tl01kq	444	17	.	.	.
cord-010027-r0tl01kq	445	1	KM	KM	NNP
cord-010027-r0tl01kq	445	2	Sutton	Sutton	NNP
cord-010027-r0tl01kq	445	3	1	1	CD
cord-010027-r0tl01kq	445	4	;	;	:
cord-010027-r0tl01kq	445	5	D	D	NNP
cord-010027-r0tl01kq	445	6	Bottomley	Bottomley	NNP
cord-010027-r0tl01kq	445	7	1	1	CD
cord-010027-r0tl01kq	445	8	;	;	:
cord-010027-r0tl01kq	445	9	D	D	NNP
cord-010027-r0tl01kq	445	10	Morton	Morton	NNP
cord-010027-r0tl01kq	445	11	2	2	CD
cord-010027-r0tl01kq	445	12	;	;	:
cord-010027-r0tl01kq	445	13	P	P	NNP
cord-010027-r0tl01kq	445	14	Quirke	Quirke	NNP
cord-010027-r0tl01kq	445	15	1	1	CD
cord-010027-r0tl01kq	445	16	;	;	:
cord-010027-r0tl01kq	445	17	P	P	NNP
cord-010027-r0tl01kq	445	18	NP	NP	NNP
cord-010027-r0tl01kq	445	19	West	West	NNP
cord-010027-r0tl01kq	445	20	1	1	CD
cord-010027-r0tl01kq	445	21	Accurate	accurate	JJ
cord-010027-r0tl01kq	445	22	and	and	CC
cord-010027-r0tl01kq	445	23	reliable	reliable	JJ
cord-010027-r0tl01kq	445	24	methods	method	NNS
cord-010027-r0tl01kq	445	25	for	for	IN
cord-010027-r0tl01kq	445	26	assessing	assess	VBG
cord-010027-r0tl01kq	445	27	the	the	DT
cord-010027-r0tl01kq	445	28	molecular	molecular	JJ
cord-010027-r0tl01kq	445	29	profile	profile	NN
cord-010027-r0tl01kq	445	30	of	of	IN
cord-010027-r0tl01kq	445	31	clinical	clinical	JJ
cord-010027-r0tl01kq	445	32	tumour	tumour	NN
cord-010027-r0tl01kq	445	33	samples	sample	NNS
cord-010027-r0tl01kq	445	34	are	be	VBP
cord-010027-r0tl01kq	445	35	important	important	JJ
cord-010027-r0tl01kq	445	36	for	for	IN
cord-010027-r0tl01kq	445	37	the	the	DT
cord-010027-r0tl01kq	445	38	delivery	delivery	NN
cord-010027-r0tl01kq	445	39	of	of	IN
cord-010027-r0tl01kq	445	40	personalised	personalised	JJ
cord-010027-r0tl01kq	445	41	medicine	medicine	NN
cord-010027-r0tl01kq	445	42	.	.	.
cord-010027-r0tl01kq	446	1	When	when	WRB
cord-010027-r0tl01kq	446	2	adopting	adopt	VBG
cord-010027-r0tl01kq	446	3	a	a	DT
cord-010027-r0tl01kq	446	4	targeted	target	VBN
cord-010027-r0tl01kq	446	5	amplicon	amplicon	NN
cord-010027-r0tl01kq	446	6	sequencing	sequencing	NN
cord-010027-r0tl01kq	446	7	method	method	NN
cord-010027-r0tl01kq	446	8	in	in	IN
cord-010027-r0tl01kq	446	9	combination	combination	NN
cord-010027-r0tl01kq	446	10	with	with	IN
cord-010027-r0tl01kq	446	11	next	next	JJ
cord-010027-r0tl01kq	446	12	generation	generation	NN
cord-010027-r0tl01kq	446	13	sequencing	sequencing	NN
cord-010027-r0tl01kq	446	14	(	(	-LRB-
cord-010027-r0tl01kq	446	15	NGS	NGS	NNP
cord-010027-r0tl01kq	446	16	)	)	-RRB-
cord-010027-r0tl01kq	446	17	,	,	,
cord-010027-r0tl01kq	446	18	it	-PRON-	PRP
cord-010027-r0tl01kq	446	19	is	be	VBZ
cord-010027-r0tl01kq	446	20	ideal	ideal	JJ
cord-010027-r0tl01kq	446	21	to	to	TO
cord-010027-r0tl01kq	446	22	call	call	VB
cord-010027-r0tl01kq	446	23	mutations	mutation	NNS
cord-010027-r0tl01kq	446	24	against	against	IN
cord-010027-r0tl01kq	446	25	a	a	DT
cord-010027-r0tl01kq	446	26	control	control	NN
cord-010027-r0tl01kq	446	27	sample	sample	NN
cord-010027-r0tl01kq	446	28	to	to	TO
cord-010027-r0tl01kq	446	29	enable	enable	VB
cord-010027-r0tl01kq	446	30	artefacts	artefact	NNS
cord-010027-r0tl01kq	446	31	to	to	TO
cord-010027-r0tl01kq	446	32	be	be	VB
cord-010027-r0tl01kq	446	33	removed	remove	VBN
cord-010027-r0tl01kq	446	34	from	from	IN
cord-010027-r0tl01kq	446	35	the	the	DT
cord-010027-r0tl01kq	446	36	analysis	analysis	NN
cord-010027-r0tl01kq	446	37	.	.	.
cord-010027-r0tl01kq	447	1	Blood	blood	NN
cord-010027-r0tl01kq	447	2	is	be	VBZ
cord-010027-r0tl01kq	447	3	considered	consider	VBN
cord-010027-r0tl01kq	447	4	the	the	DT
cord-010027-r0tl01kq	447	5	gold	gold	JJ
cord-010027-r0tl01kq	447	6	standard	standard	JJ
cord-010027-r0tl01kq	447	7	control	control	NN
cord-010027-r0tl01kq	447	8	but	but	CC
cord-010027-r0tl01kq	447	9	may	may	MD
cord-010027-r0tl01kq	447	10	not	not	RB
cord-010027-r0tl01kq	447	11	always	always	RB
cord-010027-r0tl01kq	447	12	be	be	VB
cord-010027-r0tl01kq	447	13	available	available	JJ
cord-010027-r0tl01kq	447	14	.	.	.
cord-010027-r0tl01kq	448	1	We	-PRON-	PRP
cord-010027-r0tl01kq	448	2	compared	compare	VBD
cord-010027-r0tl01kq	448	3	the	the	DT
cord-010027-r0tl01kq	448	4	use	use	NN
cord-010027-r0tl01kq	448	5	of	of	IN
cord-010027-r0tl01kq	448	6	histologically	histologically	RB
cord-010027-r0tl01kq	448	7	normal	normal	JJ
cord-010027-r0tl01kq	448	8	mucosa	mucosa	NN
cord-010027-r0tl01kq	448	9	to	to	IN
cord-010027-r0tl01kq	448	10	blood	blood	NN
cord-010027-r0tl01kq	448	11	as	as	IN
cord-010027-r0tl01kq	448	12	a	a	DT
cord-010027-r0tl01kq	448	13	control	control	NN
cord-010027-r0tl01kq	448	14	in	in	IN
cord-010027-r0tl01kq	448	15	colon	colon	NN
cord-010027-r0tl01kq	448	16	cancer	cancer	NN
cord-010027-r0tl01kq	448	17	.	.	.
cord-010027-r0tl01kq	449	1	We	-PRON-	PRP
cord-010027-r0tl01kq	449	2	examined	examine	VBD
cord-010027-r0tl01kq	449	3	mutations	mutation	NNS
cord-010027-r0tl01kq	449	4	in	in	IN
cord-010027-r0tl01kq	449	5	40	40	CD
cord-010027-r0tl01kq	449	6	colon	colon	NN
cord-010027-r0tl01kq	449	7	cancers	cancer	NNS
cord-010027-r0tl01kq	449	8	from	from	IN
cord-010027-r0tl01kq	449	9	the	the	DT
cord-010027-r0tl01kq	449	10	NCRI	NCRI	NNP
cord-010027-r0tl01kq	449	11	FOxTROT	FOxTROT	NNP
cord-010027-r0tl01kq	449	12	trial	trial	NN
cord-010027-r0tl01kq	449	13	using	use	VBG
cord-010027-r0tl01kq	449	14	the	the	DT
cord-010027-r0tl01kq	449	15	Fluidigm	Fluidigm	NNP
cord-010027-r0tl01kq	449	16	Access	Access	NNP
cord-010027-r0tl01kq	449	17	Array	Array	NNP
cord-010027-r0tl01kq	449	18	for	for	IN
cord-010027-r0tl01kq	449	19	NGS	NGS	NNP
cord-010027-r0tl01kq	449	20	library	library	NN
cord-010027-r0tl01kq	449	21	preparation	preparation	NN
cord-010027-r0tl01kq	449	22	.	.	.
cord-010027-r0tl01kq	450	1	We	-PRON-	PRP
cord-010027-r0tl01kq	450	2	assessed	assess	VBD
cord-010027-r0tl01kq	450	3	the	the	DT
cord-010027-r0tl01kq	450	4	use	use	NN
cord-010027-r0tl01kq	450	5	of	of	IN
cord-010027-r0tl01kq	450	6	both	both	DT
cord-010027-r0tl01kq	450	7	blood	blood	NN
cord-010027-r0tl01kq	450	8	and	and	CC
cord-010027-r0tl01kq	450	9	normal	normal	JJ
cord-010027-r0tl01kq	450	10	colonic	colonic	JJ
cord-010027-r0tl01kq	450	11	mucosa	mucosa	NN
cord-010027-r0tl01kq	450	12	as	as	IN
cord-010027-r0tl01kq	450	13	a	a	DT
cord-010027-r0tl01kq	450	14	control	control	NN
cord-010027-r0tl01kq	450	15	for	for	IN
cord-010027-r0tl01kq	450	16	assessing	assess	VBG
cord-010027-r0tl01kq	450	17	mutations	mutation	NNS
cord-010027-r0tl01kq	450	18	in	in	IN
cord-010027-r0tl01kq	450	19	11	11	CD
cord-010027-r0tl01kq	450	20	genes	gene	NNS
cord-010027-r0tl01kq	450	21	.	.	.
cord-010027-r0tl01kq	451	1	All	all	DT
cord-010027-r0tl01kq	451	2	samples	sample	NNS
cord-010027-r0tl01kq	451	3	were	be	VBD
cord-010027-r0tl01kq	451	4	tested	test	VBN
cord-010027-r0tl01kq	451	5	in	in	IN
cord-010027-r0tl01kq	451	6	duplicate	duplicate	NN
cord-010027-r0tl01kq	451	7	.	.	.
cord-010027-r0tl01kq	452	1	The	the	DT
cord-010027-r0tl01kq	452	2	work	work	NN
cord-010027-r0tl01kq	452	3	was	be	VBD
cord-010027-r0tl01kq	452	4	partly	partly	RB
cord-010027-r0tl01kq	452	5	funded	fund	VBN
cord-010027-r0tl01kq	452	6	by	by	IN
cord-010027-r0tl01kq	452	7	a	a	DT
cord-010027-r0tl01kq	452	8	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	452	9	Career	Career	NNP
cord-010027-r0tl01kq	452	10	Development	Development	NNP
cord-010027-r0tl01kq	452	11	Fellowship	Fellowship	NNP
cord-010027-r0tl01kq	452	12	and	and	CC
cord-010027-r0tl01kq	452	13	is	be	VBZ
cord-010027-r0tl01kq	452	14	presented	present	VBN
cord-010027-r0tl01kq	452	15	on	on	IN
cord-010027-r0tl01kq	452	16	behalf	behalf	NN
cord-010027-r0tl01kq	452	17	of	of	IN
cord-010027-r0tl01kq	452	18	the	the	DT
cord-010027-r0tl01kq	452	19	FOxTROT	FOxTROT	NNP
cord-010027-r0tl01kq	452	20	Collaborative	Collaborative	NNP
cord-010027-r0tl01kq	452	21	Group	Group	NNP
cord-010027-r0tl01kq	452	22	.	.	.
cord-010027-r0tl01kq	453	1	Mutation	mutation	NN
cord-010027-r0tl01kq	453	2	calls	call	NNS
cord-010027-r0tl01kq	453	3	made	make	VBN
cord-010027-r0tl01kq	453	4	using	use	VBG
cord-010027-r0tl01kq	453	5	normal	normal	JJ
cord-010027-r0tl01kq	453	6	mucosa	mucosa	NN
cord-010027-r0tl01kq	453	7	as	as	IN
cord-010027-r0tl01kq	453	8	a	a	DT
cord-010027-r0tl01kq	453	9	control	control	NN
cord-010027-r0tl01kq	453	10	compared	compare	VBN
cord-010027-r0tl01kq	453	11	to	to	IN
cord-010027-r0tl01kq	453	12	blood	blood	NN
cord-010027-r0tl01kq	453	13	were	be	VBD
cord-010027-r0tl01kq	453	14	in	in	IN
cord-010027-r0tl01kq	453	15	good	good	JJ
cord-010027-r0tl01kq	453	16	agreement	agreement	NN
cord-010027-r0tl01kq	453	17	;	;	:
cord-010027-r0tl01kq	453	18	a	a	DT
cord-010027-r0tl01kq	453	19	Mathew	Mathew	NNP
cord-010027-r0tl01kq	453	20	's	's	POS
cord-010027-r0tl01kq	453	21	Correlation	Correlation	NNP
cord-010027-r0tl01kq	453	22	Coefficient	Coefficient	NNP
cord-010027-r0tl01kq	453	23	above	above	IN
cord-010027-r0tl01kq	453	24	0.7	0.7	CD
cord-010027-r0tl01kq	453	25	was	be	VBD
cord-010027-r0tl01kq	453	26	seen	see	VBN
cord-010027-r0tl01kq	453	27	for	for	IN
cord-010027-r0tl01kq	453	28	all	all	DT
cord-010027-r0tl01kq	453	29	of	of	IN
cord-010027-r0tl01kq	453	30	the	the	DT
cord-010027-r0tl01kq	453	31	genes	gene	NNS
cord-010027-r0tl01kq	453	32	where	where	WRB
cord-010027-r0tl01kq	453	33	agreement	agreement	NN
cord-010027-r0tl01kq	453	34	could	could	MD
cord-010027-r0tl01kq	453	35	be	be	VB
cord-010027-r0tl01kq	453	36	assessed	assess	VBN
cord-010027-r0tl01kq	453	37	.	.	.
cord-010027-r0tl01kq	454	1	We	-PRON-	PRP
cord-010027-r0tl01kq	454	2	found	find	VBD
cord-010027-r0tl01kq	454	3	that	that	IN
cord-010027-r0tl01kq	454	4	false	false	JJ
cord-010027-r0tl01kq	454	5	positive	positive	JJ
cord-010027-r0tl01kq	454	6	mutations	mutation	NNS
cord-010027-r0tl01kq	454	7	were	be	VBD
cord-010027-r0tl01kq	454	8	due	due	JJ
cord-010027-r0tl01kq	454	9	to	to	IN
cord-010027-r0tl01kq	454	10	poorer	poor	JJR
cord-010027-r0tl01kq	454	11	amplification	amplification	NN
cord-010027-r0tl01kq	454	12	of	of	IN
cord-010027-r0tl01kq	454	13	the	the	DT
cord-010027-r0tl01kq	454	14	normal	normal	JJ
cord-010027-r0tl01kq	454	15	mucosa	mucosa	JJ
cord-010027-r0tl01kq	454	16	samples	sample	NNS
cord-010027-r0tl01kq	454	17	and	and	CC
cord-010027-r0tl01kq	454	18	false	false	JJ
cord-010027-r0tl01kq	454	19	negatives	negative	NNS
cord-010027-r0tl01kq	454	20	were	be	VBD
cord-010027-r0tl01kq	454	21	due	due	JJ
cord-010027-r0tl01kq	454	22	to	to	IN
cord-010027-r0tl01kq	454	23	mutation	mutation	NN
cord-010027-r0tl01kq	454	24	calls	call	NNS
cord-010027-r0tl01kq	454	25	in	in	IN
cord-010027-r0tl01kq	454	26	the	the	DT
cord-010027-r0tl01kq	454	27	normal	normal	JJ
cord-010027-r0tl01kq	454	28	mucosa	mucosa	NN
cord-010027-r0tl01kq	454	29	.	.	.
cord-010027-r0tl01kq	455	1	Overall	overall	RB
cord-010027-r0tl01kq	455	2	we	-PRON-	PRP
cord-010027-r0tl01kq	455	3	found	find	VBD
cord-010027-r0tl01kq	455	4	that	that	IN
cord-010027-r0tl01kq	455	5	when	when	WRB
cord-010027-r0tl01kq	455	6	assessing	assess	VBG
cord-010027-r0tl01kq	455	7	mutations	mutation	NNS
cord-010027-r0tl01kq	455	8	in	in	IN
cord-010027-r0tl01kq	455	9	hotspot	hotspot	NN
cord-010027-r0tl01kq	455	10	oncogenes	oncogene	NNS
cord-010027-r0tl01kq	455	11	,	,	,
cord-010027-r0tl01kq	455	12	testing	test	VBG
cord-010027-r0tl01kq	455	13	in	in	IN
cord-010027-r0tl01kq	455	14	duplicate	duplicate	NN
cord-010027-r0tl01kq	455	15	and	and	CC
cord-010027-r0tl01kq	455	16	the	the	DT
cord-010027-r0tl01kq	455	17	use	use	NN
cord-010027-r0tl01kq	455	18	of	of	IN
cord-010027-r0tl01kq	455	19	a	a	DT
cord-010027-r0tl01kq	455	20	normal	normal	JJ
cord-010027-r0tl01kq	455	21	control	control	NN
cord-010027-r0tl01kq	455	22	tissue	tissue	NN
cord-010027-r0tl01kq	455	23	is	be	VBZ
cord-010027-r0tl01kq	455	24	not	not	RB
cord-010027-r0tl01kq	455	25	required	require	VBN
cord-010027-r0tl01kq	455	26	to	to	TO
cord-010027-r0tl01kq	455	27	make	make	VB
cord-010027-r0tl01kq	455	28	mutation	mutation	NN
cord-010027-r0tl01kq	455	29	calls	call	NNS
cord-010027-r0tl01kq	455	30	.	.	.
cord-010027-r0tl01kq	456	1	However	however	RB
cord-010027-r0tl01kq	456	2	,	,	,
cord-010027-r0tl01kq	456	3	where	where	WRB
cord-010027-r0tl01kq	456	4	a	a	DT
cord-010027-r0tl01kq	456	5	normal	normal	JJ
cord-010027-r0tl01kq	456	6	control	control	NN
cord-010027-r0tl01kq	456	7	is	be	VBZ
cord-010027-r0tl01kq	456	8	required	require	VBN
cord-010027-r0tl01kq	456	9	,	,	,
cord-010027-r0tl01kq	456	10	normal	normal	JJ
cord-010027-r0tl01kq	456	11	mucosa	mucosa	RB
cord-010027-r0tl01kq	456	12	from	from	IN
cord-010027-r0tl01kq	456	13	the	the	DT
cord-010027-r0tl01kq	456	14	resection	resection	NN
cord-010027-r0tl01kq	456	15	margin	margin	NN
cord-010027-r0tl01kq	456	16	is	be	VBZ
cord-010027-r0tl01kq	456	17	a	a	DT
cord-010027-r0tl01kq	456	18	suitable	suitable	JJ
cord-010027-r0tl01kq	456	19	alternative	alternative	NN
cord-010027-r0tl01kq	456	20	to	to	IN
cord-010027-r0tl01kq	456	21	blood	blood	NN
cord-010027-r0tl01kq	456	22	where	where	WRB
cord-010027-r0tl01kq	456	23	it	-PRON-	PRP
cord-010027-r0tl01kq	456	24	is	be	VBZ
cord-010027-r0tl01kq	456	25	not	not	RB
cord-010027-r0tl01kq	456	26	available	available	JJ
cord-010027-r0tl01kq	456	27	.	.	.
cord-010027-r0tl01kq	457	1	We	-PRON-	PRP
cord-010027-r0tl01kq	457	2	report	report	VBP
cord-010027-r0tl01kq	457	3	a	a	DT
cord-010027-r0tl01kq	457	4	series	series	NN
cord-010027-r0tl01kq	457	5	of	of	IN
cord-010027-r0tl01kq	457	6	four	four	CD
cord-010027-r0tl01kq	457	7	unusual	unusual	JJ
cord-010027-r0tl01kq	457	8	ovarian	ovarian	NN
cord-010027-r0tl01kq	457	9	or	or	CC
cord-010027-r0tl01kq	457	10	extraovarian	extraovarian	JJ
cord-010027-r0tl01kq	457	11	neoplasms	neoplasm	NNS
cord-010027-r0tl01kq	457	12	composed	compose	VBN
cord-010027-r0tl01kq	457	13	of	of	IN
cord-010027-r0tl01kq	457	14	an	an	DT
cord-010027-r0tl01kq	457	15	admixture	admixture	NN
cord-010027-r0tl01kq	457	16	of	of	IN
cord-010027-r0tl01kq	457	17	adenosarcoma	adenosarcoma	NNS
cord-010027-r0tl01kq	457	18	and	and	CC
cord-010027-r0tl01kq	457	19	a	a	DT
cord-010027-r0tl01kq	457	20	predominant	predominant	JJ
cord-010027-r0tl01kq	457	21	component	component	NN
cord-010027-r0tl01kq	457	22	comprising	comprise	VBG
cord-010027-r0tl01kq	457	23	a	a	DT
cord-010027-r0tl01kq	457	24	sex	sex	NN
cord-010027-r0tl01kq	457	25	cord	cord	NN
cord-010027-r0tl01kq	457	26	tumour	tumour	NN
cord-010027-r0tl01kq	457	27	.	.	.
cord-010027-r0tl01kq	458	1	The	the	DT
cord-010027-r0tl01kq	458	2	neoplasms	neoplasm	NNS
cord-010027-r0tl01kq	458	3	occurred	occur	VBD
cord-010027-r0tl01kq	458	4	in	in	IN
cord-010027-r0tl01kq	458	5	women	woman	NNS
cord-010027-r0tl01kq	458	6	aged	age	VBN
cord-010027-r0tl01kq	458	7	50	50	CD
cord-010027-r0tl01kq	458	8	to	to	IN
cord-010027-r0tl01kq	458	9	69	69	CD
cord-010027-r0tl01kq	458	10	.	.	.
cord-010027-r0tl01kq	459	1	Three	three	CD
cord-010027-r0tl01kq	459	2	cases	case	NNS
cord-010027-r0tl01kq	459	3	arose	arise	VBD
cord-010027-r0tl01kq	459	4	within	within	IN
cord-010027-r0tl01kq	459	5	the	the	DT
cord-010027-r0tl01kq	459	6	ovary	ovary	NN
cord-010027-r0tl01kq	459	7	and	and	CC
cord-010027-r0tl01kq	459	8	one	one	CD
cord-010027-r0tl01kq	459	9	was	be	VBD
cord-010027-r0tl01kq	459	10	extraovarian	extraovarian	JJ
cord-010027-r0tl01kq	459	11	(	(	-LRB-
cord-010027-r0tl01kq	459	12	pelvis	pelvi	NNS
cord-010027-r0tl01kq	459	13	and	and	CC
cord-010027-r0tl01kq	459	14	abdomen	abdomen	NN
cord-010027-r0tl01kq	459	15	)	)	-RRB-
cord-010027-r0tl01kq	459	16	in	in	IN
cord-010027-r0tl01kq	459	17	location	location	NN
cord-010027-r0tl01kq	459	18	.	.	.
cord-010027-r0tl01kq	460	1	In	in	IN
cord-010027-r0tl01kq	460	2	all	all	DT
cord-010027-r0tl01kq	460	3	four	four	CD
cord-010027-r0tl01kq	460	4	cases	case	NNS
cord-010027-r0tl01kq	460	5	,	,	,
cord-010027-r0tl01kq	460	6	there	there	EX
cord-010027-r0tl01kq	460	7	were	be	VBD
cord-010027-r0tl01kq	460	8	minor	minor	JJ
cord-010027-r0tl01kq	460	9	areas	area	NNS
cord-010027-r0tl01kq	460	10	with	with	IN
cord-010027-r0tl01kq	460	11	morphological	morphological	JJ
cord-010027-r0tl01kq	460	12	features	feature	NNS
cord-010027-r0tl01kq	460	13	of	of	IN
cord-010027-r0tl01kq	460	14	adenosarcoma	adenosarcoma	NNS
cord-010027-r0tl01kq	460	15	with	with	IN
cord-010027-r0tl01kq	460	16	a	a	DT
cord-010027-r0tl01kq	460	17	phyllodes	phyllodes	NN
cord-010027-r0tl01kq	460	18	-	-	HYPH
cord-010027-r0tl01kq	460	19	like	like	JJ
cord-010027-r0tl01kq	460	20	architecture	architecture	NN
cord-010027-r0tl01kq	460	21	and	and	CC
cord-010027-r0tl01kq	460	22	periglandular	periglandular	NNP
cord-010027-r0tl01kq	460	23	increased	increase	VBD
cord-010027-r0tl01kq	460	24	cellularity	cellularity	NN
cord-010027-r0tl01kq	460	25	with	with	IN
cord-010027-r0tl01kq	460	26	mitotic	mitotic	JJ
cord-010027-r0tl01kq	460	27	figures	figure	NNS
cord-010027-r0tl01kq	460	28	.	.	.
cord-010027-r0tl01kq	461	1	In	in	IN
cord-010027-r0tl01kq	461	2	two	two	CD
cord-010027-r0tl01kq	461	3	cases	case	NNS
cord-010027-r0tl01kq	461	4	,	,	,
cord-010027-r0tl01kq	461	5	the	the	DT
cord-010027-r0tl01kq	461	6	stromal	stromal	JJ
cord-010027-r0tl01kq	461	7	component	component	NN
cord-010027-r0tl01kq	461	8	was	be	VBD
cord-010027-r0tl01kq	461	9	morphologically	morphologically	RB
cord-010027-r0tl01kq	461	10	in	in	IN
cord-010027-r0tl01kq	461	11	keeping	keep	VBG
cord-010027-r0tl01kq	461	12	with	with	IN
cord-010027-r0tl01kq	461	13	a	a	DT
cord-010027-r0tl01kq	461	14	juvenile	juvenile	JJ
cord-010027-r0tl01kq	461	15	granulosa	granulosa	JJ
cord-010027-r0tl01kq	461	16	cell	cell	NN
cord-010027-r0tl01kq	461	17	tumour	tumour	NN
cord-010027-r0tl01kq	461	18	.	.	.
cord-010027-r0tl01kq	462	1	In	in	IN
cord-010027-r0tl01kq	462	2	one	one	CD
cord-010027-r0tl01kq	462	3	case	case	NN
cord-010027-r0tl01kq	462	4	,	,	,
cord-010027-r0tl01kq	462	5	the	the	DT
cord-010027-r0tl01kq	462	6	stromal	stromal	JJ
cord-010027-r0tl01kq	462	7	component	component	NN
cord-010027-r0tl01kq	462	8	had	have	VBD
cord-010027-r0tl01kq	462	9	some	some	DT
cord-010027-r0tl01kq	462	10	features	feature	NNS
cord-010027-r0tl01kq	462	11	of	of	IN
cord-010027-r0tl01kq	462	12	both	both	DT
cord-010027-r0tl01kq	462	13	adult	adult	NN
cord-010027-r0tl01kq	462	14	granulosa	granulosa	JJ
cord-010027-r0tl01kq	462	15	cell	cell	NN
cord-010027-r0tl01kq	462	16	tumour	tumour	NN
cord-010027-r0tl01kq	462	17	and	and	CC
cord-010027-r0tl01kq	462	18	Sertoli	sertoli	JJ
cord-010027-r0tl01kq	462	19	cell	cell	NN
cord-010027-r0tl01kq	462	20	tumour	tumour	NN
cord-010027-r0tl01kq	462	21	within	within	IN
cord-010027-r0tl01kq	462	22	a	a	DT
cord-010027-r0tl01kq	462	23	fibromatous	fibromatous	JJ
cord-010027-r0tl01kq	462	24	background	background	NN
cord-010027-r0tl01kq	462	25	.	.	.
cord-010027-r0tl01kq	463	1	The	the	DT
cord-010027-r0tl01kq	463	2	fourth	fourth	JJ
cord-010027-r0tl01kq	463	3	case	case	NN
cord-010027-r0tl01kq	463	4	morphologically	morphologically	RB
cord-010027-r0tl01kq	463	5	could	could	MD
cord-010027-r0tl01kq	463	6	not	not	RB
cord-010027-r0tl01kq	463	7	be	be	VB
cord-010027-r0tl01kq	463	8	categorised	categorise	VBN
cord-010027-r0tl01kq	463	9	as	as	IN
cord-010027-r0tl01kq	463	10	any	any	DT
cord-010027-r0tl01kq	463	11	of	of	IN
cord-010027-r0tl01kq	463	12	the	the	DT
cord-010027-r0tl01kq	463	13	usual	usual	JJ
cord-010027-r0tl01kq	463	14	types	type	NNS
cord-010027-r0tl01kq	463	15	of	of	IN
cord-010027-r0tl01kq	463	16	ovarian	ovarian	JJ
cord-010027-r0tl01kq	463	17	sex	sex	NN
cord-010027-r0tl01kq	463	18	cord	cord	NN
cord-010027-r0tl01kq	463	19	tumour	tumour	NN
cord-010027-r0tl01kq	463	20	and	and	CC
cord-010027-r0tl01kq	463	21	was	be	VBD
cord-010027-r0tl01kq	463	22	categorised	categorise	VBN
cord-010027-r0tl01kq	463	23	as	as	IN
cord-010027-r0tl01kq	463	24	an	an	DT
cord-010027-r0tl01kq	463	25	unclassifiable	unclassifiable	JJ
cord-010027-r0tl01kq	463	26	sex	sex	NN
cord-010027-r0tl01kq	463	27	cord	cord	NN
cord-010027-r0tl01kq	463	28	tumour	tumour	NN
cord-010027-r0tl01kq	463	29	.	.	.
cord-010027-r0tl01kq	464	1	In	in	IN
cord-010027-r0tl01kq	464	2	all	all	DT
cord-010027-r0tl01kq	464	3	four	four	CD
cord-010027-r0tl01kq	464	4	cases	case	NNS
cord-010027-r0tl01kq	464	5	,	,	,
cord-010027-r0tl01kq	464	6	there	there	EX
cord-010027-r0tl01kq	464	7	was	be	VBD
cord-010027-r0tl01kq	464	8	immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	464	9	evidence	evidence	NN
cord-010027-r0tl01kq	464	10	of	of	IN
cord-010027-r0tl01kq	464	11	sex	sex	NN
cord-010027-r0tl01kq	464	12	cord	cord	NN
cord-010027-r0tl01kq	464	13	differentiation	differentiation	NN
cord-010027-r0tl01kq	464	14	.	.	.
cord-010027-r0tl01kq	465	1	In	in	IN
cord-010027-r0tl01kq	465	2	each	each	DT
cord-010027-r0tl01kq	465	3	case	case	NN
cord-010027-r0tl01kq	465	4	,	,	,
cord-010027-r0tl01kq	465	5	we	-PRON-	PRP
cord-010027-r0tl01kq	465	6	propose	propose	VBP
cord-010027-r0tl01kq	465	7	that	that	IN
cord-010027-r0tl01kq	465	8	the	the	DT
cord-010027-r0tl01kq	465	9	sex	sex	NN
cord-010027-r0tl01kq	465	10	cord	cord	NN
cord-010027-r0tl01kq	465	11	tumour	tumour	NN
cord-010027-r0tl01kq	465	12	arose	arise	VBD
cord-010027-r0tl01kq	465	13	from	from	IN
cord-010027-r0tl01kq	465	14	a	a	DT
cord-010027-r0tl01kq	465	15	pre	pre	JJ
cord-010027-r0tl01kq	465	16	-	-	JJ
cord-010027-r0tl01kq	465	17	existing	existing	JJ
cord-010027-r0tl01kq	465	18	adenosarcoma	adenosarcoma	NNS
cord-010027-r0tl01kq	465	19	thus	thus	RB
cord-010027-r0tl01kq	465	20	representing	represent	VBG
cord-010027-r0tl01kq	465	21	an	an	DT
cord-010027-r0tl01kq	465	22	unusual	unusual	JJ
cord-010027-r0tl01kq	465	23	form	form	NN
cord-010027-r0tl01kq	465	24	of	of	IN
cord-010027-r0tl01kq	465	25	sarcomatous	sarcomatous	JJ
cord-010027-r0tl01kq	465	26	overgrowth	overgrowth	NN
cord-010027-r0tl01kq	465	27	of	of	IN
cord-010027-r0tl01kq	465	28	sex	sex	NN
cord-010027-r0tl01kq	465	29	cord	cord	NN
cord-010027-r0tl01kq	465	30	elements	element	NNS
cord-010027-r0tl01kq	465	31	which	which	WDT
cord-010027-r0tl01kq	465	32	can	can	MD
cord-010027-r0tl01kq	465	33	occur	occur	VB
cord-010027-r0tl01kq	465	34	within	within	IN
cord-010027-r0tl01kq	465	35	adenosarcomas	adenosarcomas	NNP
cord-010027-r0tl01kq	465	36	.	.	.
cord-010027-r0tl01kq	466	1	This	this	DT
cord-010027-r0tl01kq	466	2	phenomenon	phenomenon	NN
cord-010027-r0tl01kq	466	3	is	be	VBZ
cord-010027-r0tl01kq	466	4	not	not	RB
cord-010027-r0tl01kq	466	5	well	well	RB
cord-010027-r0tl01kq	466	6	described	describe	VBN
cord-010027-r0tl01kq	466	7	in	in	IN
cord-010027-r0tl01kq	466	8	the	the	DT
cord-010027-r0tl01kq	466	9	literature	literature	NN
cord-010027-r0tl01kq	466	10	.	.	.
cord-010027-r0tl01kq	467	1	Background	background	NN
cord-010027-r0tl01kq	467	2	:	:	:
cord-010027-r0tl01kq	468	1	Human	human	JJ
cord-010027-r0tl01kq	468	2	epididymis	epididymis	NN
cord-010027-r0tl01kq	468	3	protein	protein	NN
cord-010027-r0tl01kq	468	4	4	4	CD
cord-010027-r0tl01kq	468	5	(	(	-LRB-
cord-010027-r0tl01kq	468	6	HE4	HE4	NNP
cord-010027-r0tl01kq	468	7	)	)	-RRB-
cord-010027-r0tl01kq	468	8	is	be	VBZ
cord-010027-r0tl01kq	468	9	a	a	DT
cord-010027-r0tl01kq	468	10	secreted	secrete	VBN
cord-010027-r0tl01kq	468	11	protein	protein	NN
cord-010027-r0tl01kq	468	12	that	that	WDT
cord-010027-r0tl01kq	468	13	is	be	VBZ
cord-010027-r0tl01kq	468	14	overexpressed	overexpresse	VBN
cord-010027-r0tl01kq	468	15	in	in	IN
cord-010027-r0tl01kq	468	16	some	some	DT
cord-010027-r0tl01kq	468	17	cancers	cancer	NNS
cord-010027-r0tl01kq	468	18	.	.	.
cord-010027-r0tl01kq	469	1	HE4	HE4	NNP
cord-010027-r0tl01kq	469	2	is	be	VBZ
cord-010027-r0tl01kq	469	3	emerging	emerge	VBG
cord-010027-r0tl01kq	469	4	as	as	IN
cord-010027-r0tl01kq	469	5	a	a	DT
cord-010027-r0tl01kq	469	6	useful	useful	JJ
cord-010027-r0tl01kq	469	7	biomarker	biomarker	NN
cord-010027-r0tl01kq	469	8	in	in	IN
cord-010027-r0tl01kq	469	9	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	469	10	and	and	CC
cord-010027-r0tl01kq	469	11	follow	follow	NN
cord-010027-r0tl01kq	469	12	-	-	HYPH
cord-010027-r0tl01kq	469	13	up	up	NN
cord-010027-r0tl01kq	469	14	of	of	IN
cord-010027-r0tl01kq	469	15	endometrial	endometrial	JJ
cord-010027-r0tl01kq	469	16	cancers	cancer	NNS
cord-010027-r0tl01kq	469	17	.	.	.
cord-010027-r0tl01kq	470	1	The	the	DT
cord-010027-r0tl01kq	470	2	aim	aim	NN
cord-010027-r0tl01kq	470	3	of	of	IN
cord-010027-r0tl01kq	470	4	this	this	DT
cord-010027-r0tl01kq	470	5	study	study	NN
cord-010027-r0tl01kq	470	6	was	be	VBD
cord-010027-r0tl01kq	470	7	to	to	TO
cord-010027-r0tl01kq	470	8	evaluate	evaluate	VB
cord-010027-r0tl01kq	470	9	the	the	DT
cord-010027-r0tl01kq	470	10	potential	potential	JJ
cord-010027-r0tl01kq	470	11	role	role	NN
cord-010027-r0tl01kq	470	12	of	of	IN
cord-010027-r0tl01kq	470	13	serum	serum	NN
cord-010027-r0tl01kq	470	14	HE4	HE4	NNP
cord-010027-r0tl01kq	470	15	in	in	IN
cord-010027-r0tl01kq	470	16	the	the	DT
cord-010027-r0tl01kq	470	17	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	470	18	and	and	CC
cord-010027-r0tl01kq	470	19	management	management	NN
cord-010027-r0tl01kq	470	20	of	of	IN
cord-010027-r0tl01kq	470	21	endometrial	endometrial	JJ
cord-010027-r0tl01kq	470	22	cancer	cancer	NN
cord-010027-r0tl01kq	470	23	.	.	.
cord-010027-r0tl01kq	471	1	Methods	method	NNS
cord-010027-r0tl01kq	471	2	:	:	:
cord-010027-r0tl01kq	471	3	Patients	patient	NNS
cord-010027-r0tl01kq	471	4	undergoing	undergo	VBG
cord-010027-r0tl01kq	471	5	surgery	surgery	NN
cord-010027-r0tl01kq	471	6	for	for	IN
cord-010027-r0tl01kq	471	7	endometrial	endometrial	JJ
cord-010027-r0tl01kq	471	8	disease	disease	NN
cord-010027-r0tl01kq	471	9	were	be	VBD
cord-010027-r0tl01kq	471	10	recruited	recruit	VBN
cord-010027-r0tl01kq	471	11	into	into	IN
cord-010027-r0tl01kq	471	12	this	this	DT
cord-010027-r0tl01kq	471	13	study	study	NN
cord-010027-r0tl01kq	471	14	and	and	CC
cord-010027-r0tl01kq	471	15	had	have	VBD
cord-010027-r0tl01kq	471	16	pre	pre	JJ
cord-010027-r0tl01kq	471	17	-	-	JJ
cord-010027-r0tl01kq	471	18	operative	operative	JJ
cord-010027-r0tl01kq	471	19	serum	serum	NN
cord-010027-r0tl01kq	471	20	samples	sample	NNS
cord-010027-r0tl01kq	471	21	taken	take	VBN
cord-010027-r0tl01kq	471	22	,	,	,
cord-010027-r0tl01kq	471	23	n=157	n=157	ADD
cord-010027-r0tl01kq	471	24	.	.	.
cord-010027-r0tl01kq	472	1	Demographic	demographic	JJ
cord-010027-r0tl01kq	472	2	,	,	,
cord-010027-r0tl01kq	472	3	clinical	clinical	JJ
cord-010027-r0tl01kq	472	4	,	,	,
cord-010027-r0tl01kq	472	5	radiological	radiological	JJ
cord-010027-r0tl01kq	472	6	and	and	CC
cord-010027-r0tl01kq	472	7	laboratory	laboratory	NN
cord-010027-r0tl01kq	472	8	data	datum	NNS
cord-010027-r0tl01kq	472	9	were	be	VBD
cord-010027-r0tl01kq	472	10	reviewed	review	VBN
cord-010027-r0tl01kq	472	11	.	.	.
cord-010027-r0tl01kq	473	1	HE4	HE4	NNP
cord-010027-r0tl01kq	473	2	and	and	CC
cord-010027-r0tl01kq	473	3	CA125	ca125	NN
cord-010027-r0tl01kq	473	4	serum	serum	NN
cord-010027-r0tl01kq	473	5	levels	level	NNS
cord-010027-r0tl01kq	473	6	were	be	VBD
cord-010027-r0tl01kq	473	7	analysed	analyse	VBN
cord-010027-r0tl01kq	473	8	using	use	VBG
cord-010027-r0tl01kq	473	9	the	the	DT
cord-010027-r0tl01kq	473	10	Fujirebio	Fujirebio	NNP
cord-010027-r0tl01kq	473	11	Diagnostic	Diagnostic	NNP
cord-010027-r0tl01kq	473	12	ELISA	ELISA	NNP
cord-010027-r0tl01kq	473	13	Kits	kit	NNS
cord-010027-r0tl01kq	473	14	and	and	CC
cord-010027-r0tl01kq	473	15	results	result	NNS
cord-010027-r0tl01kq	473	16	correlated	correlate	VBN
cord-010027-r0tl01kq	473	17	with	with	IN
cord-010027-r0tl01kq	473	18	clinicopathological	clinicopathological	JJ
cord-010027-r0tl01kq	473	19	details	detail	NNS
cord-010027-r0tl01kq	473	20	.	.	.
cord-010027-r0tl01kq	474	1	Standard	standard	JJ
cord-010027-r0tl01kq	474	2	cut	cut	VB
cord-010027-r0tl01kq	474	3	-	-	HYPH
cord-010027-r0tl01kq	474	4	off	off	RP
cord-010027-r0tl01kq	474	5	points	point	NNS
cord-010027-r0tl01kq	474	6	of	of	IN
cord-010027-r0tl01kq	474	7	70	70	CD
cord-010027-r0tl01kq	474	8	pmol	pmol	NN
cord-010027-r0tl01kq	474	9	/	/	SYM
cord-010027-r0tl01kq	474	10	L	l	NN
cord-010027-r0tl01kq	474	11	for	for	IN
cord-010027-r0tl01kq	474	12	HE4	HE4	NNP
cord-010027-r0tl01kq	474	13	and	and	CC
cord-010027-r0tl01kq	474	14	35	35	CD
cord-010027-r0tl01kq	474	15	U	U	NNP
cord-010027-r0tl01kq	474	16	/	/	SYM
cord-010027-r0tl01kq	474	17	ml	ml	XX
cord-010027-r0tl01kq	474	18	for	for	IN
cord-010027-r0tl01kq	474	19	CA125	ca125	NN
cord-010027-r0tl01kq	474	20	were	be	VBD
cord-010027-r0tl01kq	474	21	used	use	VBN
cord-010027-r0tl01kq	474	22	.	.	.
cord-010027-r0tl01kq	475	1	Results	result	NNS
cord-010027-r0tl01kq	475	2	:	:	:
cord-010027-r0tl01kq	475	3	HE4	HE4	NNP
cord-010027-r0tl01kq	475	4	showed	show	VBD
cord-010027-r0tl01kq	475	5	a	a	DT
cord-010027-r0tl01kq	475	6	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	475	7	of	of	IN
cord-010027-r0tl01kq	475	8	64	64	CD
cord-010027-r0tl01kq	475	9	%	%	NN
cord-010027-r0tl01kq	475	10	and	and	CC
cord-010027-r0tl01kq	475	11	specificity	specificity	NN
cord-010027-r0tl01kq	475	12	of	of	IN
cord-010027-r0tl01kq	475	13	97.50	97.50	CD
cord-010027-r0tl01kq	475	14	%	%	NN
cord-010027-r0tl01kq	475	15	for	for	IN
cord-010027-r0tl01kq	475	16	detection	detection	NN
cord-010027-r0tl01kq	475	17	of	of	IN
cord-010027-r0tl01kq	475	18	endometrial	endometrial	JJ
cord-010027-r0tl01kq	475	19	cancer	cancer	NN
cord-010027-r0tl01kq	475	20	.	.	.
cord-010027-r0tl01kq	476	1	CA125	CA125	NNP
cord-010027-r0tl01kq	476	2	had	have	VBD
cord-010027-r0tl01kq	476	3	a	a	DT
cord-010027-r0tl01kq	476	4	very	very	RB
cord-010027-r0tl01kq	476	5	low	low	JJ
cord-010027-r0tl01kq	476	6	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	476	7	of	of	IN
cord-010027-r0tl01kq	476	8	14	14	CD
cord-010027-r0tl01kq	476	9	%	%	NN
cord-010027-r0tl01kq	476	10	for	for	IN
cord-010027-r0tl01kq	476	11	endometrial	endometrial	JJ
cord-010027-r0tl01kq	476	12	cancer	cancer	NN
cord-010027-r0tl01kq	476	13	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	476	14	.	.	.
cord-010027-r0tl01kq	477	1	HE4	HE4	NNP
cord-010027-r0tl01kq	477	2	was	be	VBD
cord-010027-r0tl01kq	477	3	elevated	elevate	VBN
cord-010027-r0tl01kq	477	4	in	in	IN
cord-010027-r0tl01kq	477	5	all	all	DT
cord-010027-r0tl01kq	477	6	stages	stage	NNS
cord-010027-r0tl01kq	477	7	of	of	IN
cord-010027-r0tl01kq	477	8	endometrial	endometrial	JJ
cord-010027-r0tl01kq	477	9	cancer	cancer	NN
cord-010027-r0tl01kq	477	10	and	and	CC
cord-010027-r0tl01kq	477	11	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	477	12	the	the	DT
cord-010027-r0tl01kq	477	13	ability	ability	NN
cord-010027-r0tl01kq	477	14	to	to	TO
cord-010027-r0tl01kq	477	15	distinguish	distinguish	VB
cord-010027-r0tl01kq	477	16	between	between	IN
cord-010027-r0tl01kq	477	17	benign	benign	JJ
cord-010027-r0tl01kq	477	18	and	and	CC
cord-010027-r0tl01kq	477	19	malignant	malignant	JJ
cord-010027-r0tl01kq	477	20	groups	group	NNS
cord-010027-r0tl01kq	477	21	.	.	.
cord-010027-r0tl01kq	478	1	HE4	HE4	NNP
cord-010027-r0tl01kq	478	2	also	also	RB
cord-010027-r0tl01kq	478	3	provided	provide	VBD
cord-010027-r0tl01kq	478	4	information	information	NN
cord-010027-r0tl01kq	478	5	about	about	IN
cord-010027-r0tl01kq	478	6	myometrial	myometrial	JJ
cord-010027-r0tl01kq	478	7	space	space	NN
cord-010027-r0tl01kq	478	8	invasion	invasion	NN
cord-010027-r0tl01kq	478	9	.	.	.
cord-010027-r0tl01kq	479	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	479	2	:	:	:
cord-010027-r0tl01kq	479	3	HE4	HE4	NNP
cord-010027-r0tl01kq	479	4	has	have	VBZ
cord-010027-r0tl01kq	479	5	a	a	DT
cord-010027-r0tl01kq	479	6	role	role	NN
cord-010027-r0tl01kq	479	7	in	in	IN
cord-010027-r0tl01kq	479	8	endometrial	endometrial	JJ
cord-010027-r0tl01kq	479	9	cancer	cancer	NN
cord-010027-r0tl01kq	479	10	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	479	11	and	and	CC
cord-010027-r0tl01kq	479	12	prognosis	prognosis	NN
cord-010027-r0tl01kq	479	13	and	and	CC
cord-010027-r0tl01kq	479	14	has	have	VBZ
cord-010027-r0tl01kq	479	15	the	the	DT
cord-010027-r0tl01kq	479	16	potential	potential	NN
cord-010027-r0tl01kq	479	17	to	to	TO
cord-010027-r0tl01kq	479	18	be	be	VB
cord-010027-r0tl01kq	479	19	used	use	VBN
cord-010027-r0tl01kq	479	20	in	in	IN
cord-010027-r0tl01kq	479	21	a	a	DT
cord-010027-r0tl01kq	479	22	screening	screening	NN
cord-010027-r0tl01kq	479	23	setting	setting	NN
cord-010027-r0tl01kq	479	24	or	or	CC
cord-010027-r0tl01kq	479	25	as	as	IN
cord-010027-r0tl01kq	479	26	a	a	DT
cord-010027-r0tl01kq	479	27	triage	triage	NN
cord-010027-r0tl01kq	479	28	marker	marker	NN
cord-010027-r0tl01kq	479	29	in	in	IN
cord-010027-r0tl01kq	479	30	the	the	DT
cord-010027-r0tl01kq	479	31	primary	primary	JJ
cord-010027-r0tl01kq	479	32	care	care	NN
cord-010027-r0tl01kq	479	33	setting	setting	NN
cord-010027-r0tl01kq	479	34	.	.	.
cord-010027-r0tl01kq	480	1	For	for	IN
cord-010027-r0tl01kq	480	2	women	woman	NNS
cord-010027-r0tl01kq	480	3	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	480	4	with	with	IN
cord-010027-r0tl01kq	480	5	endometrial	endometrial	JJ
cord-010027-r0tl01kq	480	6	cancer	cancer	NN
cord-010027-r0tl01kq	480	7	,	,	,
cord-010027-r0tl01kq	480	8	HE4	HE4	NNP
cord-010027-r0tl01kq	480	9	has	have	VBZ
cord-010027-r0tl01kq	480	10	the	the	DT
cord-010027-r0tl01kq	480	11	potential	potential	NN
cord-010027-r0tl01kq	480	12	to	to	TO
cord-010027-r0tl01kq	480	13	stratify	stratify	VB
cord-010027-r0tl01kq	480	14	them	-PRON-	PRP
cord-010027-r0tl01kq	480	15	into	into	IN
cord-010027-r0tl01kq	480	16	treatment	treatment	NN
cord-010027-r0tl01kq	480	17	regimens	regimen	NNS
cord-010027-r0tl01kq	480	18	where	where	WRB
cord-010027-r0tl01kq	480	19	the	the	DT
cord-010027-r0tl01kq	480	20	most	most	RBS
cord-010027-r0tl01kq	480	21	appropriate	appropriate	JJ
cord-010027-r0tl01kq	480	22	treatment	treatment	NN
cord-010027-r0tl01kq	480	23	can	can	MD
cord-010027-r0tl01kq	480	24	be	be	VB
cord-010027-r0tl01kq	480	25	delivered	deliver	VBN
cord-010027-r0tl01kq	480	26	resulting	result	VBG
cord-010027-r0tl01kq	480	27	in	in	IN
cord-010027-r0tl01kq	480	28	improved	improved	JJ
cord-010027-r0tl01kq	480	29	quality	quality	NN
cord-010027-r0tl01kq	480	30	of	of	IN
cord-010027-r0tl01kq	480	31	life	life	NN
cord-010027-r0tl01kq	480	32	and	and	CC
cord-010027-r0tl01kq	480	33	outcome	outcome	NN
cord-010027-r0tl01kq	480	34	for	for	IN
cord-010027-r0tl01kq	480	35	endometrial	endometrial	JJ
cord-010027-r0tl01kq	480	36	cancer	cancer	NN
cord-010027-r0tl01kq	480	37	patients	patient	NNS
cord-010027-r0tl01kq	480	38	.	.	.
cord-010027-r0tl01kq	481	1	Platelets	platelet	NNS
cord-010027-r0tl01kq	481	2	Drive	drive	VBP
cord-010027-r0tl01kq	481	3	Metastatic	metastatic	JJ
cord-010027-r0tl01kq	481	4	Changes	change	NNS
cord-010027-r0tl01kq	481	5	in	in	IN
cord-010027-r0tl01kq	481	6	Ovarian	Ovarian	NNP
cord-010027-r0tl01kq	481	7	Cancer	Cancer	NNP
cord-010027-r0tl01kq	481	8	Cells	Cells	NNP
cord-010027-r0tl01kq	481	9	P	p	NN
cord-010027-r0tl01kq	481	10	CD	cd	NN
cord-010027-r0tl01kq	481	11	Spillane	Spillane	NNP
cord-010027-r0tl01kq	481	12	1	1	CD
cord-010027-r0tl01kq	481	13	;	;	:
cord-010027-r0tl01kq	481	14	NM	NM	NNP
cord-010027-r0tl01kq	481	15	Cooke	Cooke	NNP
cord-010027-r0tl01kq	481	16	2	2	CD
cord-010027-r0tl01kq	481	17	;	;	:
cord-010027-r0tl01kq	481	18	S	S	NNP
cord-010027-r0tl01kq	481	19	O'Toole	O'Toole	NNP
cord-010027-r0tl01kq	481	20	3	3	CD
cord-010027-r0tl01kq	481	21	;	;	:
cord-010027-r0tl01kq	481	22	D	D	NNP
cord-010027-r0tl01kq	481	23	Kenny	Kenny	NNP
cord-010027-r0tl01kq	481	24	2	2	CD
cord-010027-r0tl01kq	481	25	;	;	:
cord-010027-r0tl01kq	481	26	O	o	UH
cord-010027-r0tl01kq	481	27	Sheils	Sheils	NNP
cord-010027-r0tl01kq	481	28	1	1	CD
cord-010027-r0tl01kq	481	29	;	;	:
cord-010027-r0tl01kq	481	30	JJ	JJ	NNP
cord-010027-r0tl01kq	481	31	O'Leary	O'Leary	NNP
cord-010027-r0tl01kq	481	32	1	1	CD
cord-010027-r0tl01kq	481	33	1	1	CD
cord-010027-r0tl01kq	481	34	Histopathology	Histopathology	NNP
cord-010027-r0tl01kq	481	35	Department	Department	NNP
cord-010027-r0tl01kq	481	36	,	,	,
cord-010027-r0tl01kq	481	37	Trinity	Trinity	NNP
cord-010027-r0tl01kq	481	38	College	College	NNP
cord-010027-r0tl01kq	481	39	Dublin	Dublin	NNP
cord-010027-r0tl01kq	481	40	,	,	,
cord-010027-r0tl01kq	481	41	Dublin	Dublin	NNP
cord-010027-r0tl01kq	481	42	,	,	,
cord-010027-r0tl01kq	481	43	Ireland	Ireland	NNP
cord-010027-r0tl01kq	481	44	;	;	:
cord-010027-r0tl01kq	481	45	2	2	CD
cord-010027-r0tl01kq	481	46	Department	Department	NNP
cord-010027-r0tl01kq	481	47	of	of	IN
cord-010027-r0tl01kq	481	48	Molecular	Molecular	NNP
cord-010027-r0tl01kq	481	49	and	and	CC
cord-010027-r0tl01kq	481	50	Cellular	Cellular	NNP
cord-010027-r0tl01kq	481	51	Therapeutics	Therapeutics	NNP
cord-010027-r0tl01kq	481	52	,	,	,
cord-010027-r0tl01kq	481	53	RCSI	RCSI	NNP
cord-010027-r0tl01kq	481	54	,	,	,
cord-010027-r0tl01kq	481	55	Dublin	Dublin	NNP
cord-010027-r0tl01kq	481	56	,	,	,
cord-010027-r0tl01kq	481	57	Ireland	Ireland	NNP
cord-010027-r0tl01kq	481	58	;	;	:
cord-010027-r0tl01kq	481	59	3	3	CD
cord-010027-r0tl01kq	481	60	Department	Department	NNP
cord-010027-r0tl01kq	481	61	of	of	IN
cord-010027-r0tl01kq	481	62	Obstetrics	Obstetrics	NNP
cord-010027-r0tl01kq	481	63	and	and	CC
cord-010027-r0tl01kq	481	64	Gynaecology	Gynaecology	NNP
cord-010027-r0tl01kq	481	65	,	,	,
cord-010027-r0tl01kq	481	66	Trinity	Trinity	NNP
cord-010027-r0tl01kq	481	67	College	College	NNP
cord-010027-r0tl01kq	481	68	Dublin	Dublin	NNP
cord-010027-r0tl01kq	481	69	,	,	,
cord-010027-r0tl01kq	481	70	Dublin	Dublin	NNP
cord-010027-r0tl01kq	481	71	,	,	,
cord-010027-r0tl01kq	482	1	Ireland	Ireland	NNP
cord-010027-r0tl01kq	482	2	Background	Background	NNP
cord-010027-r0tl01kq	482	3	:	:	:
cord-010027-r0tl01kq	483	1	Ovarian	ovarian	JJ
cord-010027-r0tl01kq	483	2	cancer	cancer	NN
cord-010027-r0tl01kq	483	3	is	be	VBZ
cord-010027-r0tl01kq	483	4	the	the	DT
cord-010027-r0tl01kq	483	5	5th	5th	JJ
cord-010027-r0tl01kq	483	6	leading	leading	NN
cord-010027-r0tl01kq	483	7	cause	cause	NN
cord-010027-r0tl01kq	483	8	of	of	IN
cord-010027-r0tl01kq	483	9	cancer	cancer	NN
cord-010027-r0tl01kq	483	10	related	relate	VBN
cord-010027-r0tl01kq	483	11	deaths	death	NNS
cord-010027-r0tl01kq	483	12	in	in	IN
cord-010027-r0tl01kq	483	13	women	woman	NNS
cord-010027-r0tl01kq	483	14	.	.	.
cord-010027-r0tl01kq	484	1	Previously	previously	RB
cord-010027-r0tl01kq	484	2	we	-PRON-	PRP
cord-010027-r0tl01kq	484	3	described	describe	VBD
cord-010027-r0tl01kq	484	4	a	a	DT
cord-010027-r0tl01kq	484	5	dynamic	dynamic	JJ
cord-010027-r0tl01kq	484	6	interaction	interaction	NN
cord-010027-r0tl01kq	484	7	between	between	IN
cord-010027-r0tl01kq	484	8	ovarian	ovarian	JJ
cord-010027-r0tl01kq	484	9	cancer	cancer	NN
cord-010027-r0tl01kq	484	10	cells	cell	NNS
cord-010027-r0tl01kq	484	11	and	and	CC
cord-010027-r0tl01kq	484	12	platelets	platelet	NNS
cord-010027-r0tl01kq	484	13	in	in	IN
cord-010027-r0tl01kq	484	14	vitro	vitro	FW
cord-010027-r0tl01kq	484	15	,	,	,
cord-010027-r0tl01kq	484	16	involving	involve	VBG
cord-010027-r0tl01kq	484	17	platelet	platelet	NN
cord-010027-r0tl01kq	484	18	adhesion	adhesion	NN
cord-010027-r0tl01kq	484	19	,	,	,
cord-010027-r0tl01kq	484	20	activation	activation	NN
cord-010027-r0tl01kq	484	21	and	and	CC
cord-010027-r0tl01kq	484	22	induction	induction	NN
cord-010027-r0tl01kq	484	23	of	of	IN
cord-010027-r0tl01kq	484	24	pro	pro	JJ
cord-010027-r0tl01kq	484	25	-	-	JJ
cord-010027-r0tl01kq	484	26	survival	survival	JJ
cord-010027-r0tl01kq	484	27	and	and	CC
cord-010027-r0tl01kq	484	28	pro	pro	JJ
cord-010027-r0tl01kq	484	29	-	-	JJ
cord-010027-r0tl01kq	484	30	angiogenic	angiogenic	JJ
cord-010027-r0tl01kq	484	31	signals	signal	NNS
cord-010027-r0tl01kq	484	32	in	in	IN
cord-010027-r0tl01kq	484	33	the	the	DT
cord-010027-r0tl01kq	484	34	cancer	cancer	NN
cord-010027-r0tl01kq	484	35	cells	cell	NNS
cord-010027-r0tl01kq	484	36	.	.	.
cord-010027-r0tl01kq	485	1	This	this	DT
cord-010027-r0tl01kq	485	2	study	study	NN
cord-010027-r0tl01kq	485	3	looked	look	VBD
cord-010027-r0tl01kq	485	4	to	to	TO
cord-010027-r0tl01kq	485	5	further	further	RB
cord-010027-r0tl01kq	485	6	investigate	investigate	VB
cord-010027-r0tl01kq	485	7	this	this	DT
cord-010027-r0tl01kq	485	8	phenomenon	phenomenon	NN
cord-010027-r0tl01kq	485	9	in	in	IN
cord-010027-r0tl01kq	485	10	ovarian	ovarian	JJ
cord-010027-r0tl01kq	485	11	cancer	cancer	NN
cord-010027-r0tl01kq	485	12	cells	cell	NNS
cord-010027-r0tl01kq	485	13	by	by	IN
cord-010027-r0tl01kq	485	14	assessing	assess	VBG
cord-010027-r0tl01kq	485	15	the	the	DT
cord-010027-r0tl01kq	485	16	molecular	molecular	JJ
cord-010027-r0tl01kq	485	17	changes	change	NNS
cord-010027-r0tl01kq	485	18	it	-PRON-	PRP
cord-010027-r0tl01kq	485	19	induced	induce	VBD
cord-010027-r0tl01kq	485	20	.	.	.
cord-010027-r0tl01kq	486	1	Methods	method	NNS
cord-010027-r0tl01kq	486	2	:	:	:
cord-010027-r0tl01kq	486	3	Cell	cell	NN
cord-010027-r0tl01kq	486	4	lines	line	NNS
cord-010027-r0tl01kq	486	5	59	59	CD
cord-010027-r0tl01kq	486	6	M	M	NNP
cord-010027-r0tl01kq	486	7	and	and	CC
cord-010027-r0tl01kq	486	8	SKOV3	SKOV3	NNP
cord-010027-r0tl01kq	486	9	were	be	VBD
cord-010027-r0tl01kq	486	10	used	use	VBN
cord-010027-r0tl01kq	486	11	as	as	IN
cord-010027-r0tl01kq	486	12	in	in	IN
cord-010027-r0tl01kq	486	13	vitro	vitro	FW
cord-010027-r0tl01kq	486	14	models	model	NNS
cord-010027-r0tl01kq	486	15	of	of	IN
cord-010027-r0tl01kq	486	16	metastatic	metastatic	JJ
cord-010027-r0tl01kq	486	17	ovarian	ovarian	JJ
cord-010027-r0tl01kq	486	18	cancer	cancer	NN
cord-010027-r0tl01kq	486	19	.	.	.
cord-010027-r0tl01kq	487	1	Platelet	platelet	NN
cord-010027-r0tl01kq	487	2	cloaking	cloaking	NN
cord-010027-r0tl01kq	487	3	of	of	IN
cord-010027-r0tl01kq	487	4	cells	cell	NNS
cord-010027-r0tl01kq	487	5	was	be	VBD
cord-010027-r0tl01kq	487	6	quantified	quantify	VBN
cord-010027-r0tl01kq	487	7	by	by	IN
cord-010027-r0tl01kq	487	8	flow	flow	NN
cord-010027-r0tl01kq	487	9	cytometry	cytometry	NN
cord-010027-r0tl01kq	487	10	.	.	.
cord-010027-r0tl01kq	488	1	Cells	cell	NNS
cord-010027-r0tl01kq	488	2	co	co	VBP
cord-010027-r0tl01kq	488	3	-	-	JJ
cord-010027-r0tl01kq	488	4	cultured	cultured	JJ
cord-010027-r0tl01kq	488	5	with/	with/	NNP
cord-010027-r0tl01kq	488	6	without	without	IN
cord-010027-r0tl01kq	488	7	platelets	platelet	NNS
cord-010027-r0tl01kq	488	8	for	for	IN
cord-010027-r0tl01kq	488	9	24hrs	24hrs	NN
cord-010027-r0tl01kq	488	10	were	be	VBD
cord-010027-r0tl01kq	488	11	examined	examine	VBN
cord-010027-r0tl01kq	488	12	by	by	IN
cord-010027-r0tl01kq	488	13	RT	RT	NNP
cord-010027-r0tl01kq	488	14	-	-	HYPH
cord-010027-r0tl01kq	488	15	PCR	PCR	NNP
cord-010027-r0tl01kq	488	16	for	for	IN
cord-010027-r0tl01kq	488	17	EMT	EMT	NNP
cord-010027-r0tl01kq	488	18	related	relate	VBN
cord-010027-r0tl01kq	488	19	changes	change	NNS
cord-010027-r0tl01kq	488	20	and	and	CC
cord-010027-r0tl01kq	488	21	by	by	IN
cord-010027-r0tl01kq	488	22	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	488	23	Gene2.0ST	Gene2.0ST	NNP
cord-010027-r0tl01kq	488	24	arrays	array	NNS
cord-010027-r0tl01kq	488	25	for	for	IN
cord-010027-r0tl01kq	488	26	whole	whole	JJ
cord-010027-r0tl01kq	488	27	transcriptome	transcriptome	NN
cord-010027-r0tl01kq	488	28	changes	change	NNS
cord-010027-r0tl01kq	488	29	.	.	.
cord-010027-r0tl01kq	489	1	Results	result	NNS
cord-010027-r0tl01kq	489	2	:	:	:
cord-010027-r0tl01kq	490	1	Significantly	significantly	RB
cord-010027-r0tl01kq	490	2	more	more	JJR
cord-010027-r0tl01kq	490	3	platelets	platelet	NNS
cord-010027-r0tl01kq	490	4	adhered	adhere	VBN
cord-010027-r0tl01kq	490	5	to	to	IN
cord-010027-r0tl01kq	490	6	SKOV3	SKOV3	NNP
cord-010027-r0tl01kq	490	7	cells	cell	NNS
cord-010027-r0tl01kq	490	8	than	than	IN
cord-010027-r0tl01kq	490	9	59	59	CD
cord-010027-r0tl01kq	490	10	M	M	NNP
cord-010027-r0tl01kq	490	11	cells	cell	NNS
cord-010027-r0tl01kq	490	12	.	.	.
cord-010027-r0tl01kq	491	1	While	while	IN
cord-010027-r0tl01kq	491	2	there	there	EX
cord-010027-r0tl01kq	491	3	were	be	VBD
cord-010027-r0tl01kq	491	4	different	different	JJ
cord-010027-r0tl01kq	491	5	rates	rate	NNS
cord-010027-r0tl01kq	491	6	of	of	IN
cord-010027-r0tl01kq	491	7	adhesion	adhesion	NN
cord-010027-r0tl01kq	491	8	,	,	,
cord-010027-r0tl01kq	491	9	the	the	DT
cord-010027-r0tl01kq	491	10	platelets	platelet	NNS
cord-010027-r0tl01kq	491	11	induced	induce	VBD
cord-010027-r0tl01kq	491	12	similar	similar	JJ
cord-010027-r0tl01kq	491	13	changes	change	NNS
cord-010027-r0tl01kq	491	14	in	in	IN
cord-010027-r0tl01kq	491	15	EMT	EMT	NNP
cord-010027-r0tl01kq	491	16	related	related	JJ
cord-010027-r0tl01kq	491	17	genes	gene	NNS
cord-010027-r0tl01kq	491	18	in	in	IN
cord-010027-r0tl01kq	491	19	both	both	DT
cord-010027-r0tl01kq	491	20	.	.	.
cord-010027-r0tl01kq	492	1	There	there	EX
cord-010027-r0tl01kq	492	2	was	be	VBD
cord-010027-r0tl01kq	492	3	a	a	DT
cord-010027-r0tl01kq	492	4	significant	significant	JJ
cord-010027-r0tl01kq	492	5	loss	loss	NN
cord-010027-r0tl01kq	492	6	in	in	IN
cord-010027-r0tl01kq	492	7	expression	expression	NN
cord-010027-r0tl01kq	492	8	of	of	IN
cord-010027-r0tl01kq	492	9	epithelial	epithelial	JJ
cord-010027-r0tl01kq	492	10	genes	gene	NNS
cord-010027-r0tl01kq	492	11	and	and	CC
cord-010027-r0tl01kq	492	12	an	an	DT
cord-010027-r0tl01kq	492	13	increase	increase	NN
cord-010027-r0tl01kq	492	14	in	in	IN
cord-010027-r0tl01kq	492	15	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	492	16	genes	gene	NNS
cord-010027-r0tl01kq	492	17	,	,	,
cord-010027-r0tl01kq	492	18	indicating	indicate	VBG
cord-010027-r0tl01kq	492	19	the	the	DT
cord-010027-r0tl01kq	492	20	induction	induction	NN
cord-010027-r0tl01kq	492	21	of	of	IN
cord-010027-r0tl01kq	492	22	EMT	EMT	NNP
cord-010027-r0tl01kq	492	23	.	.	.
cord-010027-r0tl01kq	493	1	Whole	whole	JJ
cord-010027-r0tl01kq	493	2	transcriptome	transcriptome	NN
cord-010027-r0tl01kq	493	3	analysis	analysis	NN
cord-010027-r0tl01kq	493	4	showed	show	VBD
cord-010027-r0tl01kq	493	5	that	that	IN
cord-010027-r0tl01kq	493	6	there	there	EX
cord-010027-r0tl01kq	493	7	were	be	VBD
cord-010027-r0tl01kq	493	8	a	a	DT
cord-010027-r0tl01kq	493	9	greater	great	JJR
cord-010027-r0tl01kq	493	10	number	number	NN
cord-010027-r0tl01kq	493	11	of	of	IN
cord-010027-r0tl01kq	493	12	gene	gene	NN
cord-010027-r0tl01kq	493	13	expression	expression	NN
cord-010027-r0tl01kq	493	14	changes	change	NNS
cord-010027-r0tl01kq	493	15	occurring	occur	VBG
cord-010027-r0tl01kq	493	16	in	in	IN
cord-010027-r0tl01kq	493	17	SKOV3	SKOV3	NNP
cord-010027-r0tl01kq	493	18	cells	cell	NNS
cord-010027-r0tl01kq	493	19	compared	compare	VBN
cord-010027-r0tl01kq	493	20	to	to	IN
cord-010027-r0tl01kq	493	21	59	59	CD
cord-010027-r0tl01kq	493	22	M	M	NNP
cord-010027-r0tl01kq	493	23	cells	cell	NNS
cord-010027-r0tl01kq	493	24	,	,	,
cord-010027-r0tl01kq	493	25	correlating	correlate	VBG
cord-010027-r0tl01kq	493	26	with	with	IN
cord-010027-r0tl01kq	493	27	the	the	DT
cord-010027-r0tl01kq	493	28	adhesion	adhesion	NN
cord-010027-r0tl01kq	493	29	data	datum	NNS
cord-010027-r0tl01kq	493	30	.	.	.
cord-010027-r0tl01kq	494	1	A	a	DT
cord-010027-r0tl01kq	494	2	32	32	CD
cord-010027-r0tl01kq	494	3	gene	gene	NN
cord-010027-r0tl01kq	494	4	panel	panel	NN
cord-010027-r0tl01kq	494	5	of	of	IN
cord-010027-r0tl01kq	494	6	commonly	commonly	RB
cord-010027-r0tl01kq	494	7	affected	affect	VBN
cord-010027-r0tl01kq	494	8	genes	gene	NNS
cord-010027-r0tl01kq	494	9	in	in	IN
cord-010027-r0tl01kq	494	10	both	both	DT
cord-010027-r0tl01kq	494	11	cell	cell	NN
cord-010027-r0tl01kq	494	12	lines	line	NNS
cord-010027-r0tl01kq	494	13	was	be	VBD
cord-010027-r0tl01kq	494	14	identified	identify	VBN
cord-010027-r0tl01kq	494	15	,	,	,
cord-010027-r0tl01kq	494	16	many	many	JJ
cord-010027-r0tl01kq	494	17	of	of	IN
cord-010027-r0tl01kq	494	18	which	which	WDT
cord-010027-r0tl01kq	494	19	form	form	VBP
cord-010027-r0tl01kq	494	20	part	part	NN
cord-010027-r0tl01kq	494	21	of	of	IN
cord-010027-r0tl01kq	494	22	an	an	DT
cord-010027-r0tl01kq	494	23	interlinking	interlink	VBG
cord-010027-r0tl01kq	494	24	pathway	pathway	NN
cord-010027-r0tl01kq	494	25	that	that	WDT
cord-010027-r0tl01kq	494	26	is	be	VBZ
cord-010027-r0tl01kq	494	27	regulated	regulate	VBN
cord-010027-r0tl01kq	494	28	by	by	IN
cord-010027-r0tl01kq	494	29	TGFβ1	TGFβ1	NNS
cord-010027-r0tl01kq	494	30	and	and	CC
cord-010027-r0tl01kq	494	31	associated	associate	VBN
cord-010027-r0tl01kq	494	32	with	with	IN
cord-010027-r0tl01kq	494	33	cell	cell	NN
cord-010027-r0tl01kq	494	34	adhesion	adhesion	NN
cord-010027-r0tl01kq	494	35	/	/	SYM
cord-010027-r0tl01kq	494	36	ECM	ECM	NNP
cord-010027-r0tl01kq	494	37	remodelling	remodelling	NN
cord-010027-r0tl01kq	494	38	.	.	.
cord-010027-r0tl01kq	495	1	Though	though	IN
cord-010027-r0tl01kq	495	2	only	only	RB
cord-010027-r0tl01kq	495	3	32	32	CD
cord-010027-r0tl01kq	495	4	genes	gene	NNS
cord-010027-r0tl01kq	495	5	overlapped	overlap	VBN
cord-010027-r0tl01kq	495	6	,	,	,
cord-010027-r0tl01kq	495	7	the	the	DT
cord-010027-r0tl01kq	495	8	biological	biological	JJ
cord-010027-r0tl01kq	495	9	processes	process	NNS
cord-010027-r0tl01kq	495	10	affected	affect	VBN
cord-010027-r0tl01kq	495	11	in	in	IN
cord-010027-r0tl01kq	495	12	both	both	DT
cord-010027-r0tl01kq	495	13	cell	cell	NN
cord-010027-r0tl01kq	495	14	lines	line	NNS
cord-010027-r0tl01kq	495	15	were	be	VBD
cord-010027-r0tl01kq	495	16	very	very	RB
cord-010027-r0tl01kq	495	17	similar	similar	JJ
cord-010027-r0tl01kq	495	18	,	,	,
cord-010027-r0tl01kq	495	19	with	with	IN
cord-010027-r0tl01kq	495	20	103	103	CD
cord-010027-r0tl01kq	495	21	of	of	IN
cord-010027-r0tl01kq	495	22	the	the	DT
cord-010027-r0tl01kq	495	23	148	148	CD
cord-010027-r0tl01kq	495	24	processes	process	NNS
cord-010027-r0tl01kq	495	25	enriched	enrich	VBN
cord-010027-r0tl01kq	495	26	in	in	IN
cord-010027-r0tl01kq	495	27	the	the	DT
cord-010027-r0tl01kq	495	28	59	59	CD
cord-010027-r0tl01kq	495	29	M	M	NNP
cord-010027-r0tl01kq	495	30	data	datum	NNS
cord-010027-r0tl01kq	495	31	set	set	VBN
cord-010027-r0tl01kq	495	32	also	also	RB
cord-010027-r0tl01kq	495	33	seen	see	VBN
cord-010027-r0tl01kq	495	34	in	in	IN
cord-010027-r0tl01kq	495	35	the	the	DT
cord-010027-r0tl01kq	495	36	SKOV3	SKOV3	NNP
cord-010027-r0tl01kq	495	37	data	data	NN
cord-010027-r0tl01kq	495	38	set	set	NN
cord-010027-r0tl01kq	495	39	.	.	.
cord-010027-r0tl01kq	496	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	496	2	:	:	:
cord-010027-r0tl01kq	497	1	This	this	DT
cord-010027-r0tl01kq	497	2	study	study	NN
cord-010027-r0tl01kq	497	3	shows	show	VBZ
cord-010027-r0tl01kq	497	4	that	that	IN
cord-010027-r0tl01kq	497	5	platelets	platelet	NNS
cord-010027-r0tl01kq	497	6	can	can	MD
cord-010027-r0tl01kq	497	7	enhance	enhance	VB
cord-010027-r0tl01kq	497	8	the	the	DT
cord-010027-r0tl01kq	497	9	metastatic	metastatic	JJ
cord-010027-r0tl01kq	497	10	potential	potential	NN
cord-010027-r0tl01kq	497	11	of	of	IN
cord-010027-r0tl01kq	497	12	ovarian	ovarian	JJ
cord-010027-r0tl01kq	497	13	cancer	cancer	NN
cord-010027-r0tl01kq	497	14	cells	cell	NNS
cord-010027-r0tl01kq	497	15	through	through	IN
cord-010027-r0tl01kq	497	16	the	the	DT
cord-010027-r0tl01kq	497	17	induction	induction	NN
cord-010027-r0tl01kq	497	18	of	of	IN
cord-010027-r0tl01kq	497	19	EMT	EMT	NNP
cord-010027-r0tl01kq	497	20	and	and	CC
cord-010027-r0tl01kq	497	21	ECM	ECM	NNP
cord-010027-r0tl01kq	497	22	changes	change	NNS
cord-010027-r0tl01kq	497	23	.	.	.
cord-010027-r0tl01kq	498	1	In	in	IN
cord-010027-r0tl01kq	498	2	addition	addition	NN
cord-010027-r0tl01kq	498	3	,	,	,
cord-010027-r0tl01kq	498	4	it	-PRON-	PRP
cord-010027-r0tl01kq	498	5	has	have	VBZ
cord-010027-r0tl01kq	498	6	identified	identify	VBN
cord-010027-r0tl01kq	498	7	a	a	DT
cord-010027-r0tl01kq	498	8	set	set	NN
cord-010027-r0tl01kq	498	9	of	of	IN
cord-010027-r0tl01kq	498	10	32	32	CD
cord-010027-r0tl01kq	498	11	genes	gene	NNS
cord-010027-r0tl01kq	498	12	that	that	WDT
cord-010027-r0tl01kq	498	13	hold	hold	VBP
cord-010027-r0tl01kq	498	14	potential	potential	NN
cord-010027-r0tl01kq	498	15	to	to	TO
cord-010027-r0tl01kq	498	16	be	be	VB
cord-010027-r0tl01kq	498	17	in	in	IN
cord-010027-r0tl01kq	498	18	vivo	vivo	NN
cord-010027-r0tl01kq	498	19	markers	marker	NNS
cord-010027-r0tl01kq	498	20	of	of	IN
cord-010027-r0tl01kq	498	21	this	this	DT
cord-010027-r0tl01kq	498	22	interaction	interaction	NN
cord-010027-r0tl01kq	498	23	.	.	.
cord-010027-r0tl01kq	499	1	Background	background	NN
cord-010027-r0tl01kq	499	2	:	:	:
cord-010027-r0tl01kq	500	1	During	during	IN
cord-010027-r0tl01kq	500	2	the	the	DT
cord-010027-r0tl01kq	500	3	metastatic	metastatic	JJ
cord-010027-r0tl01kq	500	4	cascade	cascade	NN
cord-010027-r0tl01kq	500	5	,	,	,
cord-010027-r0tl01kq	500	6	circulating	circulate	VBG
cord-010027-r0tl01kq	500	7	tumour	tumour	NN
cord-010027-r0tl01kq	500	8	cells	cell	NNS
cord-010027-r0tl01kq	500	9	rapidly	rapidly	RB
cord-010027-r0tl01kq	500	10	and	and	CC
cord-010027-r0tl01kq	500	11	efficiently	efficiently	RB
cord-010027-r0tl01kq	500	12	adopt	adopt	VB
cord-010027-r0tl01kq	500	13	a	a	DT
cord-010027-r0tl01kq	500	14	platelet	platelet	NN
cord-010027-r0tl01kq	500	15	cloak	cloak	NN
cord-010027-r0tl01kq	500	16	.	.	.
cord-010027-r0tl01kq	501	1	Platelet	platelet	NN
cord-010027-r0tl01kq	501	2	cloaking	cloaking	NN
cord-010027-r0tl01kq	501	3	of	of	IN
cord-010027-r0tl01kq	501	4	tumour	tumour	NN
cord-010027-r0tl01kq	501	5	cells	cell	NNS
cord-010027-r0tl01kq	501	6	promotes	promote	VBZ
cord-010027-r0tl01kq	501	7	metastatic	metastatic	JJ
cord-010027-r0tl01kq	501	8	disease	disease	NN
cord-010027-r0tl01kq	501	9	by	by	IN
cord-010027-r0tl01kq	501	10	promoting	promote	VBG
cord-010027-r0tl01kq	501	11	cellular	cellular	JJ
cord-010027-r0tl01kq	501	12	proliferation	proliferation	NN
cord-010027-r0tl01kq	501	13	,	,	,
cord-010027-r0tl01kq	501	14	angiogenesis	angiogenesis	NN
cord-010027-r0tl01kq	501	15	and	and	CC
cord-010027-r0tl01kq	501	16	EMT	EMT	NNP
cord-010027-r0tl01kq	501	17	while	while	IN
cord-010027-r0tl01kq	501	18	inhibiting	inhibit	VBG
cord-010027-r0tl01kq	501	19	autophagy	autophagy	NN
cord-010027-r0tl01kq	501	20	and	and	CC
cord-010027-r0tl01kq	501	21	apoptosis	apoptosis	NN
cord-010027-r0tl01kq	501	22	.	.	.
cord-010027-r0tl01kq	502	1	The	the	DT
cord-010027-r0tl01kq	502	2	aim	aim	NN
cord-010027-r0tl01kq	502	3	of	of	IN
cord-010027-r0tl01kq	502	4	this	this	DT
cord-010027-r0tl01kq	502	5	study	study	NN
cord-010027-r0tl01kq	502	6	is	be	VBZ
cord-010027-r0tl01kq	502	7	to	to	TO
cord-010027-r0tl01kq	502	8	examine	examine	VB
cord-010027-r0tl01kq	502	9	whether	whether	IN
cord-010027-r0tl01kq	502	10	the	the	DT
cord-010027-r0tl01kq	502	11	platelet	platelet	NN
cord-010027-r0tl01kq	502	12	cloak	cloak	NN
cord-010027-r0tl01kq	502	13	contributes	contribute	VBZ
cord-010027-r0tl01kq	502	14	to	to	TO
cord-010027-r0tl01kq	502	15	tumour	tumour	NN
cord-010027-r0tl01kq	502	16	cell	cell	NN
cord-010027-r0tl01kq	502	17	evasion	evasion	NN
cord-010027-r0tl01kq	502	18	of	of	IN
cord-010027-r0tl01kq	502	19	NK	NK	NNP
cord-010027-r0tl01kq	502	20	cell	cell	NN
cord-010027-r0tl01kq	502	21	mediated	mediate	VBD
cord-010027-r0tl01kq	502	22	immune	immune	JJ
cord-010027-r0tl01kq	502	23	surveillance	surveillance	NN
cord-010027-r0tl01kq	502	24	.	.	.
cord-010027-r0tl01kq	503	1	Methods	method	NNS
cord-010027-r0tl01kq	503	2	:	:	:
cord-010027-r0tl01kq	503	3	Freshly	freshly	RB
cord-010027-r0tl01kq	503	4	isolated	isolate	VBN
cord-010027-r0tl01kq	503	5	PBMCs	pbmc	NNS
cord-010027-r0tl01kq	503	6	were	be	VBD
cord-010027-r0tl01kq	503	7	harvested	harvest	VBN
cord-010027-r0tl01kq	503	8	from	from	IN
cord-010027-r0tl01kq	503	9	healthy	healthy	JJ
cord-010027-r0tl01kq	503	10	donors	donor	NNS
cord-010027-r0tl01kq	503	11	and	and	CC
cord-010027-r0tl01kq	503	12	stimulated	stimulate	VBD
cord-010027-r0tl01kq	503	13	for	for	IN
cord-010027-r0tl01kq	503	14	18	18	CD
cord-010027-r0tl01kq	503	15	hours	hour	NNS
cord-010027-r0tl01kq	503	16	with	with	IN
cord-010027-r0tl01kq	503	17	IL-2	IL-2	NNP
cord-010027-r0tl01kq	503	18	(	(	-LRB-
cord-010027-r0tl01kq	503	19	500U	500U	NNP
cord-010027-r0tl01kq	503	20	/	/	SYM
cord-010027-r0tl01kq	503	21	mL	ml	NN
cord-010027-r0tl01kq	503	22	)	)	-RRB-
cord-010027-r0tl01kq	503	23	.	.	.
cord-010027-r0tl01kq	504	1	PBMCs	pbmc	NNS
cord-010027-r0tl01kq	504	2	were	be	VBD
cord-010027-r0tl01kq	504	3	co	co	JJ
cord-010027-r0tl01kq	504	4	-	-	VBN
cord-010027-r0tl01kq	504	5	incubated	incubate	VBN
cord-010027-r0tl01kq	505	1	with	with	IN
cord-010027-r0tl01kq	505	2	ovarian	ovarian	NN
cord-010027-r0tl01kq	505	3	(	(	-LRB-
cord-010027-r0tl01kq	505	4	59	59	CD
cord-010027-r0tl01kq	505	5	M	M	NNP
cord-010027-r0tl01kq	505	6	and	and	CC
cord-010027-r0tl01kq	505	7	SKOV3	SKOV3	NNP
cord-010027-r0tl01kq	505	8	)	)	-RRB-
cord-010027-r0tl01kq	505	9	,	,	,
cord-010027-r0tl01kq	505	10	melanoma	melanoma	NN
cord-010027-r0tl01kq	505	11	(	(	-LRB-
cord-010027-r0tl01kq	505	12	Sk	Sk	NNP
cord-010027-r0tl01kq	505	13	-	-	HYPH
cord-010027-r0tl01kq	505	14	Mel-28	Mel-28	NNP
cord-010027-r0tl01kq	505	15	)	)	-RRB-
cord-010027-r0tl01kq	505	16	and	and	CC
cord-010027-r0tl01kq	505	17	CML	CML	NNP
cord-010027-r0tl01kq	505	18	(	(	-LRB-
cord-010027-r0tl01kq	505	19	K562	k562	CD
cord-010027-r0tl01kq	505	20	)	)	-RRB-
cord-010027-r0tl01kq	505	21	cell	cell	NN
cord-010027-r0tl01kq	505	22	lines	line	NNS
cord-010027-r0tl01kq	505	23	that	that	WDT
cord-010027-r0tl01kq	505	24	were	be	VBD
cord-010027-r0tl01kq	505	25	either	either	RB
cord-010027-r0tl01kq	505	26	uncloaked	uncloak	VBN
cord-010027-r0tl01kq	505	27	,	,	,
cord-010027-r0tl01kq	505	28	or	or	CC
cord-010027-r0tl01kq	505	29	cloaked	cloak	VBN
cord-010027-r0tl01kq	505	30	with	with	IN
cord-010027-r0tl01kq	505	31	washed	washed	JJ
cord-010027-r0tl01kq	505	32	platelets	platelet	NNS
cord-010027-r0tl01kq	505	33	from	from	IN
cord-010027-r0tl01kq	505	34	healthy	healthy	JJ
cord-010027-r0tl01kq	505	35	donors	donor	NNS
cord-010027-r0tl01kq	505	36	.	.	.
cord-010027-r0tl01kq	506	1	The	the	DT
cord-010027-r0tl01kq	506	2	NK	NK	NNP
cord-010027-r0tl01kq	506	3	-	-	HYPH
cord-010027-r0tl01kq	506	4	tumour	tumour	NN
cord-010027-r0tl01kq	506	5	cell	cell	NN
cord-010027-r0tl01kq	506	6	receptor	receptor	NN
cord-010027-r0tl01kq	506	7	ligand	ligand	NN
cord-010027-r0tl01kq	506	8	systems	system	NNS
cord-010027-r0tl01kq	506	9	,	,	,
cord-010027-r0tl01kq	506	10	NKG2D	nkg2d	NN
cord-010027-r0tl01kq	506	11	-	-	HYPH
cord-010027-r0tl01kq	506	12	MICA	MICA	NNP
cord-010027-r0tl01kq	506	13	/	/	SYM
cord-010027-r0tl01kq	506	14	MICB	MICB	NNP
cord-010027-r0tl01kq	506	15	and	and	CC
cord-010027-r0tl01kq	506	16	CD96	CD96	NNP
cord-010027-r0tl01kq	506	17	/	/	SYM
cord-010027-r0tl01kq	506	18	CD226-CD155	cd226-cd155	PRP
cord-010027-r0tl01kq	506	19	were	be	VBD
cord-010027-r0tl01kq	506	20	examined	examine	VBN
cord-010027-r0tl01kq	506	21	using	use	VBG
cord-010027-r0tl01kq	506	22	NK	NK	NNP
cord-010027-r0tl01kq	506	23	cell	cell	NN
cord-010027-r0tl01kq	506	24	CD107a	CD107a	NNP
cord-010027-r0tl01kq	506	25	expression	expression	NN
cord-010027-r0tl01kq	506	26	and	and	CC
cord-010027-r0tl01kq	506	27	interferon	interferon	NN
cord-010027-r0tl01kq	506	28	-	-	HYPH
cord-010027-r0tl01kq	506	29	gamma	gamma	NN
cord-010027-r0tl01kq	506	30	production	production	NN
cord-010027-r0tl01kq	506	31	to	to	TO
cord-010027-r0tl01kq	506	32	quantify	quantify	VB
cord-010027-r0tl01kq	506	33	NK	NK	NNP
cord-010027-r0tl01kq	506	34	cell	cell	NN
cord-010027-r0tl01kq	506	35	mediated	mediate	VBN
cord-010027-r0tl01kq	506	36	recognition	recognition	NN
cord-010027-r0tl01kq	506	37	and	and	CC
cord-010027-r0tl01kq	506	38	'	'	``
cord-010027-r0tl01kq	506	39	killing	killing	NN
cord-010027-r0tl01kq	506	40	'	'	''
cord-010027-r0tl01kq	506	41	of	of	IN
cord-010027-r0tl01kq	506	42	cancer	cancer	NN
cord-010027-r0tl01kq	506	43	cells	cell	NNS
cord-010027-r0tl01kq	506	44	.	.	.
cord-010027-r0tl01kq	507	1	Results	result	NNS
cord-010027-r0tl01kq	508	1	:	:	:
cord-010027-r0tl01kq	508	2	We	-PRON-	PRP
cord-010027-r0tl01kq	508	3	first	first	RB
cord-010027-r0tl01kq	508	4	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	508	5	that	that	IN
cord-010027-r0tl01kq	508	6	ovarian	ovarian	NN
cord-010027-r0tl01kq	508	7	and	and	CC
cord-010027-r0tl01kq	508	8	melanoma	melanoma	NN
cord-010027-r0tl01kq	508	9	cancer	cancer	NN
cord-010027-r0tl01kq	508	10	cell	cell	NN
cord-010027-r0tl01kq	508	11	lines	line	NNS
cord-010027-r0tl01kq	508	12	when	when	WRB
cord-010027-r0tl01kq	508	13	cloaked	cloak	VBN
cord-010027-r0tl01kq	508	14	with	with	IN
cord-010027-r0tl01kq	508	15	washed	washed	JJ
cord-010027-r0tl01kq	508	16	platelets	platelet	NNS
cord-010027-r0tl01kq	508	17	strongly	strongly	RB
cord-010027-r0tl01kq	508	18	inhibited	inhibit	VBD
cord-010027-r0tl01kq	508	19	NK	NK	NNP
cord-010027-r0tl01kq	508	20	cell	cell	NN
cord-010027-r0tl01kq	508	21	antitumor	antitumor	NN
cord-010027-r0tl01kq	508	22	reactivity	reactivity	NN
cord-010027-r0tl01kq	508	23	.	.	.
cord-010027-r0tl01kq	509	1	Platelet	platelet	NN
cord-010027-r0tl01kq	509	2	cloaking	cloaking	NN
cord-010027-r0tl01kq	509	3	induced	induce	VBN
cord-010027-r0tl01kq	509	4	down	down	IN
cord-010027-r0tl01kq	509	5	-	-	HYPH
cord-010027-r0tl01kq	509	6	regulation	regulation	NN
cord-010027-r0tl01kq	509	7	of	of	IN
cord-010027-r0tl01kq	509	8	the	the	DT
cord-010027-r0tl01kq	509	9	stress	stress	NN
cord-010027-r0tl01kq	509	10	ligands	ligand	NNS
cord-010027-r0tl01kq	509	11	MICA	MICA	NNP
cord-010027-r0tl01kq	509	12	and	and	CC
cord-010027-r0tl01kq	509	13	MICB	MICB	NNP
cord-010027-r0tl01kq	509	14	on	on	IN
cord-010027-r0tl01kq	509	15	the	the	DT
cord-010027-r0tl01kq	509	16	tumour	tumour	NN
cord-010027-r0tl01kq	509	17	cell	cell	NN
cord-010027-r0tl01kq	509	18	coupled	couple	VBN
cord-010027-r0tl01kq	509	19	with	with	IN
cord-010027-r0tl01kq	509	20	their	-PRON-	PRP$
cord-010027-r0tl01kq	509	21	release	release	NN
cord-010027-r0tl01kq	509	22	into	into	IN
cord-010027-r0tl01kq	509	23	the	the	DT
cord-010027-r0tl01kq	509	24	microenvironment	microenvironment	NN
cord-010027-r0tl01kq	509	25	,	,	,
cord-010027-r0tl01kq	509	26	a	a	DT
cord-010027-r0tl01kq	509	27	known	know	VBN
cord-010027-r0tl01kq	509	28	NK	NK	NNP
cord-010027-r0tl01kq	509	29	cell	cell	NN
cord-010027-r0tl01kq	509	30	immune	immune	JJ
cord-010027-r0tl01kq	509	31	decoy	decoy	NN
cord-010027-r0tl01kq	509	32	strategy	strategy	NN
cord-010027-r0tl01kq	509	33	.	.	.
cord-010027-r0tl01kq	510	1	In	in	IN
cord-010027-r0tl01kq	510	2	addition	addition	NN
cord-010027-r0tl01kq	510	3	,	,	,
cord-010027-r0tl01kq	510	4	platelets	platelet	NNS
cord-010027-r0tl01kq	510	5	significantly	significantly	RB
cord-010027-r0tl01kq	510	6	down	down	RB
cord-010027-r0tl01kq	510	7	-	-	HYPH
cord-010027-r0tl01kq	510	8	regulated	regulate	VBN
cord-010027-r0tl01kq	510	9	both	both	CC
cord-010027-r0tl01kq	510	10	CD96	CD96	NNP
cord-010027-r0tl01kq	510	11	(	(	-LRB-
cord-010027-r0tl01kq	510	12	NK	NK	NNP
cord-010027-r0tl01kq	510	13	cell	cell	NN
cord-010027-r0tl01kq	510	14	)	)	-RRB-
cord-010027-r0tl01kq	510	15	and	and	CC
cord-010027-r0tl01kq	510	16	CD155	cd155	NN
cord-010027-r0tl01kq	510	17	(	(	-LRB-
cord-010027-r0tl01kq	510	18	tumour	tumour	NN
cord-010027-r0tl01kq	510	19	cell	cell	NN
cord-010027-r0tl01kq	510	20	)	)	-RRB-
cord-010027-r0tl01kq	510	21	,	,	,
cord-010027-r0tl01kq	510	22	inhibiting	inhibit	VBG
cord-010027-r0tl01kq	510	23	NK	NK	NNP
cord-010027-r0tl01kq	510	24	cell	cell	NN
cord-010027-r0tl01kq	510	25	activity	activity	NN
cord-010027-r0tl01kq	510	26	.	.	.
cord-010027-r0tl01kq	511	1	Both	both	DT
cord-010027-r0tl01kq	511	2	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	511	3	occur	occur	VBP
cord-010027-r0tl01kq	511	4	in	in	IN
cord-010027-r0tl01kq	511	5	tandem	tandem	NN
cord-010027-r0tl01kq	511	6	to	to	TO
cord-010027-r0tl01kq	511	7	comprehensively	comprehensively	RB
cord-010027-r0tl01kq	511	8	incapacitate	incapacitate	VB
cord-010027-r0tl01kq	511	9	NK	NK	NNP
cord-010027-r0tl01kq	511	10	cells	cell	NNS
cord-010027-r0tl01kq	511	11	and	and	CC
cord-010027-r0tl01kq	511	12	promote	promote	VB
cord-010027-r0tl01kq	511	13	tumour	tumour	NN
cord-010027-r0tl01kq	511	14	immune	immune	JJ
cord-010027-r0tl01kq	511	15	evasion	evasion	NN
cord-010027-r0tl01kq	511	16	.	.	.
cord-010027-r0tl01kq	512	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	512	2	:	:	:
cord-010027-r0tl01kq	513	1	Ovarian	ovarian	NN
cord-010027-r0tl01kq	513	2	and	and	CC
cord-010027-r0tl01kq	513	3	melanoma	melanoma	NN
cord-010027-r0tl01kq	513	4	tumour	tumour	NN
cord-010027-r0tl01kq	513	5	cells	cell	NNS
cord-010027-r0tl01kq	513	6	are	be	VBP
cord-010027-r0tl01kq	513	7	efficiently	efficiently	RB
cord-010027-r0tl01kq	513	8	cloaked	cloak	VBN
cord-010027-r0tl01kq	513	9	by	by	IN
cord-010027-r0tl01kq	513	10	platelets	platelet	NNS
cord-010027-r0tl01kq	513	11	,	,	,
cord-010027-r0tl01kq	513	12	which	which	WDT
cord-010027-r0tl01kq	513	13	facilitates	facilitate	VBZ
cord-010027-r0tl01kq	513	14	immune	immune	JJ
cord-010027-r0tl01kq	513	15	evasion	evasion	NN
cord-010027-r0tl01kq	513	16	by	by	IN
cord-010027-r0tl01kq	513	17	actively	actively	RB
cord-010027-r0tl01kq	513	18	suppressing	suppress	VBG
cord-010027-r0tl01kq	513	19	NK	NK	NNP
cord-010027-r0tl01kq	513	20	cell	cell	NN
cord-010027-r0tl01kq	513	21	cytotoxicity	cytotoxicity	NN
cord-010027-r0tl01kq	513	22	and	and	CC
cord-010027-r0tl01kq	513	23	cytokine	cytokine	NN
cord-010027-r0tl01kq	513	24	production	production	NN
cord-010027-r0tl01kq	513	25	.	.	.
cord-010027-r0tl01kq	514	1	Purpose	purpose	NN
cord-010027-r0tl01kq	514	2	of	of	IN
cord-010027-r0tl01kq	514	3	the	the	DT
cord-010027-r0tl01kq	514	4	study	study	NN
cord-010027-r0tl01kq	514	5	:	:	:
cord-010027-r0tl01kq	514	6	Glioblastomas	Glioblastomas	NNP
cord-010027-r0tl01kq	514	7	(	(	-LRB-
cord-010027-r0tl01kq	514	8	GBM	GBM	NNP
cord-010027-r0tl01kq	514	9	)	)	-RRB-
cord-010027-r0tl01kq	514	10	are	be	VBP
cord-010027-r0tl01kq	514	11	the	the	DT
cord-010027-r0tl01kq	514	12	most	most	RBS
cord-010027-r0tl01kq	514	13	common	common	JJ
cord-010027-r0tl01kq	514	14	and	and	CC
cord-010027-r0tl01kq	514	15	most	most	RBS
cord-010027-r0tl01kq	514	16	aggressive	aggressive	JJ
cord-010027-r0tl01kq	514	17	primary	primary	JJ
cord-010027-r0tl01kq	514	18	malignant	malignant	JJ
cord-010027-r0tl01kq	514	19	brain	brain	NN
cord-010027-r0tl01kq	514	20	tumours	tumour	NNS
cord-010027-r0tl01kq	514	21	in	in	IN
cord-010027-r0tl01kq	514	22	adults	adult	NNS
cord-010027-r0tl01kq	514	23	.	.	.
cord-010027-r0tl01kq	515	1	One	one	CD
cord-010027-r0tl01kq	515	2	of	of	IN
cord-010027-r0tl01kq	515	3	their	-PRON-	PRP$
cord-010027-r0tl01kq	515	4	histopathological	histopathological	JJ
cord-010027-r0tl01kq	515	5	hallmarks	hallmarks	NNP
cord-010027-r0tl01kq	515	6	is	be	VBZ
cord-010027-r0tl01kq	515	7	the	the	DT
cord-010027-r0tl01kq	515	8	microvascular	microvascular	JJ
cord-010027-r0tl01kq	515	9	proliferation	proliferation	NN
cord-010027-r0tl01kq	515	10	;	;	:
cord-010027-r0tl01kq	515	11	these	these	DT
cord-010027-r0tl01kq	515	12	tumours	tumour	NNS
cord-010027-r0tl01kq	515	13	are	be	VBP
cord-010027-r0tl01kq	515	14	among	among	IN
cord-010027-r0tl01kq	515	15	the	the	DT
cord-010027-r0tl01kq	515	16	most	most	JJS
cord-010027-r0tl01kq	515	17	angiogenic	angiogenic	NN
cord-010027-r0tl01kq	515	18	of	of	IN
cord-010027-r0tl01kq	515	19	malignancies	malignancy	NNS
cord-010027-r0tl01kq	515	20	by	by	IN
cord-010027-r0tl01kq	515	21	displaying	display	VBG
cord-010027-r0tl01kq	515	22	the	the	DT
cord-010027-r0tl01kq	515	23	highest	high	JJS
cord-010027-r0tl01kq	515	24	degree	degree	NN
cord-010027-r0tl01kq	515	25	of	of	IN
cord-010027-r0tl01kq	515	26	microvascular	microvascular	JJ
cord-010027-r0tl01kq	515	27	proliferation	proliferation	NN
cord-010027-r0tl01kq	515	28	.	.	.
cord-010027-r0tl01kq	516	1	IGFIIR	IGFIIR	NNP
cord-010027-r0tl01kq	516	2	/	/	SYM
cord-010027-r0tl01kq	516	3	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	516	4	is	be	VBZ
cord-010027-r0tl01kq	516	5	a	a	DT
cord-010027-r0tl01kq	516	6	receptor	receptor	NN
cord-010027-r0tl01kq	516	7	that	that	WDT
cord-010027-r0tl01kq	516	8	belongs	belong	VBZ
cord-010027-r0tl01kq	516	9	to	to	IN
cord-010027-r0tl01kq	516	10	the	the	DT
cord-010027-r0tl01kq	516	11	insulin	insulin	NN
cord-010027-r0tl01kq	516	12	-	-	HYPH
cord-010027-r0tl01kq	516	13	like	like	JJ
cord-010027-r0tl01kq	516	14	growth	growth	NN
cord-010027-r0tl01kq	516	15	factor	factor	NN
cord-010027-r0tl01kq	516	16	(	(	-LRB-
cord-010027-r0tl01kq	516	17	IGF	IGF	NNP
cord-010027-r0tl01kq	516	18	)	)	-RRB-
cord-010027-r0tl01kq	516	19	system	system	NN
cord-010027-r0tl01kq	516	20	.	.	.
cord-010027-r0tl01kq	517	1	The	the	DT
cord-010027-r0tl01kq	517	2	involvement	involvement	NN
cord-010027-r0tl01kq	517	3	of	of	IN
cord-010027-r0tl01kq	517	4	IGF	IGF	NNP
cord-010027-r0tl01kq	517	5	-	-	HYPH
cord-010027-r0tl01kq	517	6	IIR	IIR	NNP
cord-010027-r0tl01kq	517	7	/	/	SYM
cord-010027-r0tl01kq	517	8	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	517	9	in	in	IN
cord-010027-r0tl01kq	517	10	the	the	DT
cord-010027-r0tl01kq	517	11	process	process	NN
cord-010027-r0tl01kq	517	12	of	of	IN
cord-010027-r0tl01kq	517	13	angiogenesis	angiogenesis	NN
cord-010027-r0tl01kq	517	14	has	have	VBZ
cord-010027-r0tl01kq	517	15	been	be	VBN
cord-010027-r0tl01kq	517	16	postulated	postulate	VBN
cord-010027-r0tl01kq	517	17	in	in	IN
cord-010027-r0tl01kq	517	18	rare	rare	JJ
cord-010027-r0tl01kq	517	19	earlier	early	JJR
cord-010027-r0tl01kq	517	20	studies	study	NNS
cord-010027-r0tl01kq	517	21	.	.	.
cord-010027-r0tl01kq	518	1	To	to	IN
cord-010027-r0tl01kq	518	2	our	-PRON-	PRP$
cord-010027-r0tl01kq	518	3	knowledge	knowledge	NN
cord-010027-r0tl01kq	518	4	,	,	,
cord-010027-r0tl01kq	518	5	the	the	DT
cord-010027-r0tl01kq	518	6	role	role	NN
cord-010027-r0tl01kq	518	7	of	of	IN
cord-010027-r0tl01kq	518	8	IGF	IGF	NNP
cord-010027-r0tl01kq	518	9	-	-	HYPH
cord-010027-r0tl01kq	518	10	IIR	IIR	NNP
cord-010027-r0tl01kq	518	11	/	/	SYM
cord-010027-r0tl01kq	518	12	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	518	13	in	in	IN
cord-010027-r0tl01kq	518	14	the	the	DT
cord-010027-r0tl01kq	518	15	neovascularisation	neovascularisation	NN
cord-010027-r0tl01kq	518	16	of	of	IN
cord-010027-r0tl01kq	518	17	human	human	JJ
cord-010027-r0tl01kq	518	18	GBM	GBM	NNP
cord-010027-r0tl01kq	518	19	has	have	VBZ
cord-010027-r0tl01kq	518	20	never	never	RB
cord-010027-r0tl01kq	518	21	been	be	VBN
cord-010027-r0tl01kq	518	22	studied	study	VBN
cord-010027-r0tl01kq	518	23	.	.	.
cord-010027-r0tl01kq	519	1	Methods	method	NNS
cord-010027-r0tl01kq	519	2	:	:	:
cord-010027-r0tl01kq	520	1	IGF	IGF	NNP
cord-010027-r0tl01kq	520	2	-	-	HYPH
cord-010027-r0tl01kq	520	3	IIR	IIR	NNP
cord-010027-r0tl01kq	520	4	/	/	SYM
cord-010027-r0tl01kq	520	5	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	520	6	expression	expression	NN
cord-010027-r0tl01kq	520	7	was	be	VBD
cord-010027-r0tl01kq	520	8	evaluated	evaluate	VBN
cord-010027-r0tl01kq	520	9	in	in	IN
cord-010027-r0tl01kq	520	10	the	the	DT
cord-010027-r0tl01kq	520	11	vascular	vascular	JJ
cord-010027-r0tl01kq	520	12	compartment	compartment	NN
cord-010027-r0tl01kq	520	13	from	from	IN
cord-010027-r0tl01kq	520	14	322	322	CD
cord-010027-r0tl01kq	520	15	human	human	NN
cord-010027-r0tl01kq	520	16	GBM	GBM	NNP
cord-010027-r0tl01kq	520	17	and	and	CC
cord-010027-r0tl01kq	520	18	from	from	IN
cord-010027-r0tl01kq	520	19	10	10	CD
cord-010027-r0tl01kq	520	20	normal	normal	JJ
cord-010027-r0tl01kq	520	21	adult	adult	NN
cord-010027-r0tl01kq	520	22	brain	brain	NN
cord-010027-r0tl01kq	520	23	samples	sample	NNS
cord-010027-r0tl01kq	520	24	by	by	IN
cord-010027-r0tl01kq	520	25	means	mean	NNS
cord-010027-r0tl01kq	520	26	of	of	IN
cord-010027-r0tl01kq	520	27	quantitative	quantitative	JJ
cord-010027-r0tl01kq	520	28	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	520	29	on	on	IN
cord-010027-r0tl01kq	520	30	tissue	tissue	NN
cord-010027-r0tl01kq	520	31	microarray	microarray	NN
cord-010027-r0tl01kq	520	32	sections	section	NNS
cord-010027-r0tl01kq	520	33	.	.	.
cord-010027-r0tl01kq	521	1	In	in	IN
cord-010027-r0tl01kq	521	2	vitro	vitro	FW
cord-010027-r0tl01kq	521	3	cell	cell	NN
cord-010027-r0tl01kq	521	4	line	line	NN
cord-010027-r0tl01kq	521	5	experiments	experiment	NNS
cord-010027-r0tl01kq	521	6	were	be	VBD
cord-010027-r0tl01kq	521	7	carried	carry	VBN
cord-010027-r0tl01kq	521	8	out	out	RP
cord-010027-r0tl01kq	521	9	in	in	IN
cord-010027-r0tl01kq	521	10	order	order	NN
cord-010027-r0tl01kq	521	11	to	to	TO
cord-010027-r0tl01kq	521	12	characterise	characterise	VB
cord-010027-r0tl01kq	521	13	the	the	DT
cord-010027-r0tl01kq	521	14	IGFIIR	IGFIIR	NNP
cord-010027-r0tl01kq	521	15	/	/	SYM
cord-010027-r0tl01kq	521	16	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	521	17	role	role	NN
cord-010027-r0tl01kq	521	18	in	in	IN
cord-010027-r0tl01kq	521	19	angiogenesis	angiogenesis	NN
cord-010027-r0tl01kq	521	20	.	.	.
cord-010027-r0tl01kq	522	1	Summary	summary	NN
cord-010027-r0tl01kq	522	2	of	of	IN
cord-010027-r0tl01kq	522	3	results	result	NNS
cord-010027-r0tl01kq	522	4	:	:	:
cord-010027-r0tl01kq	523	1	IGF	IGF	NNP
cord-010027-r0tl01kq	523	2	-	-	HYPH
cord-010027-r0tl01kq	523	3	IIR	IIR	NNP
cord-010027-r0tl01kq	523	4	/	/	SYM
cord-010027-r0tl01kq	523	5	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	523	6	was	be	VBD
cord-010027-r0tl01kq	523	7	strongly	strongly	RB
cord-010027-r0tl01kq	523	8	expressed	express	VBN
cord-010027-r0tl01kq	523	9	in	in	IN
cord-010027-r0tl01kq	523	10	the	the	DT
cord-010027-r0tl01kq	523	11	cytoplasm	cytoplasm	NN
cord-010027-r0tl01kq	523	12	of	of	IN
cord-010027-r0tl01kq	523	13	endothelial	endothelial	JJ
cord-010027-r0tl01kq	523	14	cells	cell	NNS
cord-010027-r0tl01kq	523	15	in	in	IN
cord-010027-r0tl01kq	523	16	hyperplastic	hyperplastic	JJ
cord-010027-r0tl01kq	523	17	vessels	vessel	NNS
cord-010027-r0tl01kq	523	18	and	and	CC
cord-010027-r0tl01kq	523	19	exhibited	exhibit	VBD
cord-010027-r0tl01kq	523	20	a	a	DT
cord-010027-r0tl01kq	523	21	dot	dot	NN
cord-010027-r0tl01kq	523	22	-	-	HYPH
cord-010027-r0tl01kq	523	23	staining	stain	VBG
cord-010027-r0tl01kq	523	24	pattern	pattern	NN
cord-010027-r0tl01kq	523	25	.	.	.
cord-010027-r0tl01kq	524	1	We	-PRON-	PRP
cord-010027-r0tl01kq	524	2	found	find	VBD
cord-010027-r0tl01kq	524	3	a	a	DT
cord-010027-r0tl01kq	524	4	higher	high	JJR
cord-010027-r0tl01kq	524	5	expression	expression	NN
cord-010027-r0tl01kq	524	6	of	of	IN
cord-010027-r0tl01kq	524	7	IGF	IGF	NNP
cord-010027-r0tl01kq	524	8	-	-	HYPH
cord-010027-r0tl01kq	524	9	IIR	IIR	NNP
cord-010027-r0tl01kq	524	10	/	/	SYM
cord-010027-r0tl01kq	524	11	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	524	12	in	in	IN
cord-010027-r0tl01kq	524	13	GBM	GBM	NNP
cord-010027-r0tl01kq	524	14	vessels	vessel	NNS
cord-010027-r0tl01kq	524	15	compared	compare	VBN
cord-010027-r0tl01kq	524	16	to	to	IN
cord-010027-r0tl01kq	524	17	normal	normal	JJ
cord-010027-r0tl01kq	524	18	brain	brain	NN
cord-010027-r0tl01kq	524	19	vessels	vessel	NNS
cord-010027-r0tl01kq	524	20	(	(	-LRB-
cord-010027-r0tl01kq	524	21	p=0.05	p=0.05	JJ
cord-010027-r0tl01kq	524	22	)	)	-RRB-
cord-010027-r0tl01kq	524	23	.	.	.
cord-010027-r0tl01kq	525	1	Furthermore	furthermore	RB
cord-010027-r0tl01kq	525	2	,	,	,
cord-010027-r0tl01kq	525	3	preliminary	preliminary	JJ
cord-010027-r0tl01kq	525	4	in	in	IN
cord-010027-r0tl01kq	525	5	vitro	vitro	FW
cord-010027-r0tl01kq	525	6	experiments	experiment	NNS
cord-010027-r0tl01kq	525	7	suggest	suggest	VBP
cord-010027-r0tl01kq	525	8	a	a	DT
cord-010027-r0tl01kq	525	9	role	role	NN
cord-010027-r0tl01kq	525	10	of	of	IN
cord-010027-r0tl01kq	525	11	IGF	IGF	NNP
cord-010027-r0tl01kq	525	12	-	-	HYPH
cord-010027-r0tl01kq	525	13	IIR	IIR	NNP
cord-010027-r0tl01kq	525	14	/	/	SYM
cord-010027-r0tl01kq	525	15	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	525	16	in	in	IN
cord-010027-r0tl01kq	525	17	tube	tube	NN
cord-010027-r0tl01kq	525	18	formation	formation	NN
cord-010027-r0tl01kq	525	19	but	but	CC
cord-010027-r0tl01kq	525	20	not	not	RB
cord-010027-r0tl01kq	525	21	in	in	IN
cord-010027-r0tl01kq	525	22	growth	growth	NN
cord-010027-r0tl01kq	525	23	of	of	IN
cord-010027-r0tl01kq	525	24	the	the	DT
cord-010027-r0tl01kq	525	25	EA.hy926	ea.hy926	JJ
cord-010027-r0tl01kq	525	26	endothelial	endothelial	JJ
cord-010027-r0tl01kq	525	27	cell	cell	NN
cord-010027-r0tl01kq	525	28	line	line	NN
cord-010027-r0tl01kq	525	29	.	.	.
cord-010027-r0tl01kq	526	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	526	2	:	:	:
cord-010027-r0tl01kq	527	1	This	this	DT
cord-010027-r0tl01kq	527	2	work	work	NN
cord-010027-r0tl01kq	527	3	shows	show	VBZ
cord-010027-r0tl01kq	527	4	a	a	DT
cord-010027-r0tl01kq	527	5	possible	possible	JJ
cord-010027-r0tl01kq	527	6	role	role	NN
cord-010027-r0tl01kq	527	7	of	of	IN
cord-010027-r0tl01kq	527	8	IGFIIR	IGFIIR	NNP
cord-010027-r0tl01kq	527	9	/	/	SYM
cord-010027-r0tl01kq	527	10	Man-6-P	Man-6-P	NNP
cord-010027-r0tl01kq	527	11	in	in	IN
cord-010027-r0tl01kq	527	12	the	the	DT
cord-010027-r0tl01kq	527	13	process	process	NN
cord-010027-r0tl01kq	527	14	of	of	IN
cord-010027-r0tl01kq	527	15	neovascularisation	neovascularisation	NN
cord-010027-r0tl01kq	527	16	of	of	IN
cord-010027-r0tl01kq	527	17	GBM	GBM	NNP
cord-010027-r0tl01kq	527	18	angiogenesis	angiogenesis	NN
cord-010027-r0tl01kq	527	19	.	.	.
cord-010027-r0tl01kq	528	1	Additional	additional	JJ
cord-010027-r0tl01kq	528	2	investigations	investigation	NNS
cord-010027-r0tl01kq	528	3	are	be	VBP
cord-010027-r0tl01kq	528	4	required	require	VBN
cord-010027-r0tl01kq	528	5	to	to	TO
cord-010027-r0tl01kq	528	6	confirm	confirm	VB
cord-010027-r0tl01kq	528	7	the	the	DT
cord-010027-r0tl01kq	528	8	role	role	NN
cord-010027-r0tl01kq	528	9	of	of	IN
cord-010027-r0tl01kq	528	10	this	this	DT
cord-010027-r0tl01kq	528	11	receptor	receptor	NN
cord-010027-r0tl01kq	528	12	as	as	IN
cord-010027-r0tl01kq	528	13	a	a	DT
cord-010027-r0tl01kq	528	14	direct	direct	JJ
cord-010027-r0tl01kq	528	15	actor	actor	NN
cord-010027-r0tl01kq	528	16	of	of	IN
cord-010027-r0tl01kq	528	17	angiogenesis	angiogenesis	NN
cord-010027-r0tl01kq	528	18	in	in	IN
cord-010027-r0tl01kq	528	19	GBM	GBM	NNP
cord-010027-r0tl01kq	528	20	.	.	.
cord-010027-r0tl01kq	529	1	Purpose	purpose	NN
cord-010027-r0tl01kq	529	2	of	of	IN
cord-010027-r0tl01kq	529	3	the	the	DT
cord-010027-r0tl01kq	529	4	study	study	NN
cord-010027-r0tl01kq	529	5	:	:	:
cord-010027-r0tl01kq	529	6	Vasa	Vasa	NNP
cord-010027-r0tl01kq	529	7	vasorum	vasorum	NNP
cord-010027-r0tl01kq	529	8	(	(	-LRB-
cord-010027-r0tl01kq	529	9	VV	VV	NNP
cord-010027-r0tl01kq	529	10	)	)	-RRB-
cord-010027-r0tl01kq	529	11	are	be	VBP
cord-010027-r0tl01kq	529	12	microvessels	microvessel	NNS
cord-010027-r0tl01kq	529	13	which	which	WDT
cord-010027-r0tl01kq	529	14	supply	supply	VBP
cord-010027-r0tl01kq	529	15	vessels	vessel	NNS
cord-010027-r0tl01kq	529	16	that	that	WDT
cord-010027-r0tl01kq	529	17	can	can	MD
cord-010027-r0tl01kq	529	18	not	not	RB
cord-010027-r0tl01kq	529	19	be	be	VB
cord-010027-r0tl01kq	529	20	nourished	nourish	VBN
cord-010027-r0tl01kq	529	21	by	by	IN
cord-010027-r0tl01kq	529	22	diffusion	diffusion	NN
cord-010027-r0tl01kq	529	23	from	from	IN
cord-010027-r0tl01kq	529	24	their	-PRON-	PRP$
cord-010027-r0tl01kq	529	25	own	own	JJ
cord-010027-r0tl01kq	529	26	lumina	lumina	NN
cord-010027-r0tl01kq	529	27	.	.	.
cord-010027-r0tl01kq	530	1	VV	VV	NNP
cord-010027-r0tl01kq	530	2	are	be	VBP
cord-010027-r0tl01kq	530	3	believed	believe	VBN
cord-010027-r0tl01kq	530	4	to	to	TO
cord-010027-r0tl01kq	530	5	be	be	VB
cord-010027-r0tl01kq	530	6	a	a	DT
cord-010027-r0tl01kq	530	7	key	key	JJ
cord-010027-r0tl01kq	530	8	element	element	NN
cord-010027-r0tl01kq	530	9	in	in	IN
cord-010027-r0tl01kq	530	10	the	the	DT
cord-010027-r0tl01kq	530	11	pathogenesis	pathogenesis	NN
cord-010027-r0tl01kq	530	12	of	of	IN
cord-010027-r0tl01kq	530	13	vascular	vascular	JJ
cord-010027-r0tl01kq	530	14	diseases	disease	NNS
cord-010027-r0tl01kq	530	15	.	.	.
cord-010027-r0tl01kq	531	1	A	a	DT
cord-010027-r0tl01kq	531	2	number	number	NN
cord-010027-r0tl01kq	531	3	of	of	IN
cord-010027-r0tl01kq	531	4	different	different	JJ
cord-010027-r0tl01kq	531	5	imaging	imaging	NN
cord-010027-r0tl01kq	531	6	methods	method	NNS
cord-010027-r0tl01kq	531	7	have	have	VBP
cord-010027-r0tl01kq	531	8	been	be	VBN
cord-010027-r0tl01kq	531	9	used	use	VBN
cord-010027-r0tl01kq	531	10	to	to	TO
cord-010027-r0tl01kq	531	11	study	study	VB
cord-010027-r0tl01kq	531	12	the	the	DT
cord-010027-r0tl01kq	531	13	VV	VV	NNP
cord-010027-r0tl01kq	532	1	but	but	CC
cord-010027-r0tl01kq	532	2	there	there	EX
cord-010027-r0tl01kq	532	3	is	be	VBZ
cord-010027-r0tl01kq	532	4	still	still	RB
cord-010027-r0tl01kq	532	5	no	no	DT
cord-010027-r0tl01kq	532	6	definitive	definitive	JJ
cord-010027-r0tl01kq	532	7	consensus	consensus	NN
cord-010027-r0tl01kq	532	8	on	on	IN
cord-010027-r0tl01kq	532	9	their	-PRON-	PRP$
cord-010027-r0tl01kq	532	10	structure	structure	NN
cord-010027-r0tl01kq	532	11	.	.	.
cord-010027-r0tl01kq	533	1	The	the	DT
cord-010027-r0tl01kq	533	2	aim	aim	NN
cord-010027-r0tl01kq	533	3	was	be	VBD
cord-010027-r0tl01kq	533	4	to	to	TO
cord-010027-r0tl01kq	533	5	describe	describe	VB
cord-010027-r0tl01kq	533	6	the	the	DT
cord-010027-r0tl01kq	533	7	normal	normal	JJ
cord-010027-r0tl01kq	533	8	microvessel	microvessel	NN
cord-010027-r0tl01kq	533	9	anatomy	anatomy	NN
cord-010027-r0tl01kq	533	10	of	of	IN
cord-010027-r0tl01kq	533	11	temporal	temporal	JJ
cord-010027-r0tl01kq	533	12	arteries	artery	NNS
cord-010027-r0tl01kq	533	13	.	.	.
cord-010027-r0tl01kq	534	1	Methods	method	NNS
cord-010027-r0tl01kq	534	2	:	:	:
cord-010027-r0tl01kq	534	3	Human	human	JJ
cord-010027-r0tl01kq	534	4	temporal	temporal	JJ
cord-010027-r0tl01kq	534	5	artery	artery	NN
cord-010027-r0tl01kq	534	6	,	,	,
cord-010027-r0tl01kq	534	7	obtained	obtain	VBD
cord-010027-r0tl01kq	534	8	following	follow	VBG
cord-010027-r0tl01kq	534	9	routine	routine	JJ
cord-010027-r0tl01kq	534	10	biopsy	biopsy	NN
cord-010027-r0tl01kq	534	11	with	with	IN
cord-010027-r0tl01kq	534	12	ethical	ethical	JJ
cord-010027-r0tl01kq	534	13	approval	approval	NN
cord-010027-r0tl01kq	534	14	and	and	CC
cord-010027-r0tl01kq	534	15	patient	patient	NN
cord-010027-r0tl01kq	534	16	consent	consent	NN
cord-010027-r0tl01kq	534	17	.	.	.
cord-010027-r0tl01kq	535	1	Samples	sample	NNS
cord-010027-r0tl01kq	535	2	were	be	VBD
cord-010027-r0tl01kq	535	3	embedded	embed	VBN
cord-010027-r0tl01kq	535	4	into	into	IN
cord-010027-r0tl01kq	535	5	paraffin	paraffin	NN
cord-010027-r0tl01kq	535	6	blocks	block	NNS
cord-010027-r0tl01kq	535	7	and	and	CC
cord-010027-r0tl01kq	535	8	serially	serially	RB
cord-010027-r0tl01kq	535	9	sectioned	section	VBN
cord-010027-r0tl01kq	535	10	at	at	IN
cord-010027-r0tl01kq	535	11	5	5	CD
cord-010027-r0tl01kq	535	12	micron	micron	NN
cord-010027-r0tl01kq	535	13	intervals	interval	NNS
cord-010027-r0tl01kq	535	14	.	.	.
cord-010027-r0tl01kq	536	1	Alternate	alternate	JJ
cord-010027-r0tl01kq	536	2	sections	section	NNS
cord-010027-r0tl01kq	536	3	were	be	VBD
cord-010027-r0tl01kq	536	4	stained	stain	VBN
cord-010027-r0tl01kq	536	5	with	with	IN
cord-010027-r0tl01kq	536	6	H&E	H&E	NNP
cord-010027-r0tl01kq	536	7	and	and	CC
cord-010027-r0tl01kq	536	8	scanned	scan	VBD
cord-010027-r0tl01kq	536	9	to	to	TO
cord-010027-r0tl01kq	536	10	create	create	VB
cord-010027-r0tl01kq	536	11	virtual	virtual	JJ
cord-010027-r0tl01kq	536	12	slides	slide	NNS
cord-010027-r0tl01kq	536	13	.	.	.
cord-010027-r0tl01kq	537	1	The	the	DT
cord-010027-r0tl01kq	537	2	slides	slide	NNS
cord-010027-r0tl01kq	537	3	were	be	VBD
cord-010027-r0tl01kq	537	4	aligned	align	VBN
cord-010027-r0tl01kq	537	5	,	,	,
cord-010027-r0tl01kq	537	6	VV	VV	NNP
cord-010027-r0tl01kq	537	7	were	be	VBD
cord-010027-r0tl01kq	537	8	segmented	segmented	JJ
cord-010027-r0tl01kq	537	9	(	(	-LRB-
cord-010027-r0tl01kq	537	10	annotated	annotate	VBN
cord-010027-r0tl01kq	537	11	)	)	-RRB-
cord-010027-r0tl01kq	537	12	and	and	CC
cord-010027-r0tl01kq	537	13	iso	iso	NN
cord-010027-r0tl01kq	537	14	-	-	:
cord-010027-r0tl01kq	537	15	surfaced	surface	VBN
cord-010027-r0tl01kq	537	16	to	to	TO
cord-010027-r0tl01kq	537	17	generate	generate	VB
cord-010027-r0tl01kq	537	18	3D	3d	JJ
cord-010027-r0tl01kq	537	19	reconstructions	reconstruction	NNS
cord-010027-r0tl01kq	537	20	.	.	.
cord-010027-r0tl01kq	538	1	Summary	summary	NN
cord-010027-r0tl01kq	538	2	of	of	IN
cord-010027-r0tl01kq	538	3	results	result	NNS
cord-010027-r0tl01kq	538	4	:	:	:
cord-010027-r0tl01kq	538	5	The	the	DT
cord-010027-r0tl01kq	538	6	reconstruction	reconstruction	NN
cord-010027-r0tl01kq	538	7	shows	show	VBZ
cord-010027-r0tl01kq	538	8	the	the	DT
cord-010027-r0tl01kq	538	9	structural	structural	JJ
cord-010027-r0tl01kq	538	10	arrangement	arrangement	NN
cord-010027-r0tl01kq	538	11	of	of	IN
cord-010027-r0tl01kq	538	12	the	the	DT
cord-010027-r0tl01kq	538	13	VV	VV	NNP
cord-010027-r0tl01kq	538	14	as	as	IN
cord-010027-r0tl01kq	538	15	a	a	DT
cord-010027-r0tl01kq	538	16	complex	complex	JJ
cord-010027-r0tl01kq	538	17	plexus	plexus	NN
cord-010027-r0tl01kq	538	18	.	.	.
cord-010027-r0tl01kq	539	1	No	no	DT
cord-010027-r0tl01kq	539	2	connection	connection	NN
cord-010027-r0tl01kq	539	3	to	to	IN
cord-010027-r0tl01kq	539	4	the	the	DT
cord-010027-r0tl01kq	539	5	vascular	vascular	JJ
cord-010027-r0tl01kq	539	6	lumen	lumen	NN
cord-010027-r0tl01kq	539	7	was	be	VBD
cord-010027-r0tl01kq	539	8	visualised	visualise	VBN
cord-010027-r0tl01kq	539	9	.	.	.
cord-010027-r0tl01kq	540	1	In	in	IN
cord-010027-r0tl01kq	540	2	this	this	DT
cord-010027-r0tl01kq	540	3	segment	segment	NN
cord-010027-r0tl01kq	540	4	a	a	DT
cord-010027-r0tl01kq	540	5	hierarchical	hierarchical	JJ
cord-010027-r0tl01kq	540	6	branching	branch	VBG
cord-010027-r0tl01kq	540	7	structure	structure	NN
cord-010027-r0tl01kq	540	8	was	be	VBD
cord-010027-r0tl01kq	540	9	not	not	RB
cord-010027-r0tl01kq	540	10	observed	observe	VBN
cord-010027-r0tl01kq	540	11	.	.	.
cord-010027-r0tl01kq	541	1	VV	VV	NNP
cord-010027-r0tl01kq	541	2	were	be	VBD
cord-010027-r0tl01kq	541	3	almost	almost	RB
cord-010027-r0tl01kq	541	4	exclusively	exclusively	RB
cord-010027-r0tl01kq	541	5	restricted	restricted	JJ
cord-010027-r0tl01kq	541	6	to	to	IN
cord-010027-r0tl01kq	541	7	the	the	DT
cord-010027-r0tl01kq	541	8	adventitia	adventitia	NN
cord-010027-r0tl01kq	541	9	of	of	IN
cord-010027-r0tl01kq	541	10	the	the	DT
cord-010027-r0tl01kq	541	11	vessel	vessel	NN
cord-010027-r0tl01kq	541	12	wall	wall	NN
cord-010027-r0tl01kq	541	13	.	.	.
cord-010027-r0tl01kq	542	1	Mean	mean	JJ
cord-010027-r0tl01kq	542	2	±	±	NNP
cord-010027-r0tl01kq	542	3	SD	sd	NN
cord-010027-r0tl01kq	542	4	area	area	NN
cord-010027-r0tl01kq	542	5	of	of	IN
cord-010027-r0tl01kq	542	6	the	the	DT
cord-010027-r0tl01kq	542	7	VV	VV	NNP
cord-010027-r0tl01kq	542	8	(	(	-LRB-
cord-010027-r0tl01kq	542	9	n	n	NN
cord-010027-r0tl01kq	542	10	=	=	SYM
cord-010027-r0tl01kq	542	11	5283	5283	CD
cord-010027-r0tl01kq	542	12	)	)	-RRB-
cord-010027-r0tl01kq	542	13	is	be	VBZ
cord-010027-r0tl01kq	542	14	2287.23µm2	2287.23µm2	NNP
cord-010027-r0tl01kq	542	15	(	(	-LRB-
cord-010027-r0tl01kq	542	16	±4956.03	±4956.03	NN
cord-010027-r0tl01kq	542	17	)	)	-RRB-
cord-010027-r0tl01kq	542	18	.	.	.
cord-010027-r0tl01kq	543	1	The	the	DT
cord-010027-r0tl01kq	543	2	mean	mean	JJ
cord-010027-r0tl01kq	543	3	±	±	NNP
cord-010027-r0tl01kq	543	4	SD	sd	NN
cord-010027-r0tl01kq	543	5	number	number	NN
cord-010027-r0tl01kq	543	6	of	of	IN
cord-010027-r0tl01kq	543	7	vessels	vessel	NNS
cord-010027-r0tl01kq	543	8	per	per	IN
cord-010027-r0tl01kq	543	9	slide	slide	NN
cord-010027-r0tl01kq	543	10	is	be	VBZ
cord-010027-r0tl01kq	543	11	60.76	60.76	CD
cord-010027-r0tl01kq	543	12	(	(	-LRB-
cord-010027-r0tl01kq	543	13	±15.37	±15.37	NNP
cord-010027-r0tl01kq	543	14	)	)	-RRB-
cord-010027-r0tl01kq	543	15	.	.	.
cord-010027-r0tl01kq	544	1	These	these	DT
cord-010027-r0tl01kq	544	2	metrics	metric	NNS
cord-010027-r0tl01kq	544	3	are	be	VBP
cord-010027-r0tl01kq	544	4	based	base	VBN
cord-010027-r0tl01kq	544	5	on	on	IN
cord-010027-r0tl01kq	544	6	one	one	CD
cord-010027-r0tl01kq	544	7	arterial	arterial	JJ
cord-010027-r0tl01kq	544	8	specimen	specimen	NN
cord-010027-r0tl01kq	544	9	.	.	.
cord-010027-r0tl01kq	545	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	545	2	:	:	:
cord-010027-r0tl01kq	546	1	This	this	DT
cord-010027-r0tl01kq	546	2	method	method	NN
cord-010027-r0tl01kq	546	3	allows	allow	VBZ
cord-010027-r0tl01kq	546	4	us	-PRON-	PRP
cord-010027-r0tl01kq	546	5	to	to	TO
cord-010027-r0tl01kq	546	6	study	study	VB
cord-010027-r0tl01kq	546	7	the	the	DT
cord-010027-r0tl01kq	546	8	three	three	CD
cord-010027-r0tl01kq	546	9	-	-	HYPH
cord-010027-r0tl01kq	546	10	dimensional	dimensional	JJ
cord-010027-r0tl01kq	546	11	spatial	spatial	JJ
cord-010027-r0tl01kq	546	12	relationships	relationship	NNS
cord-010027-r0tl01kq	546	13	of	of	IN
cord-010027-r0tl01kq	546	14	microvessels	microvessel	NNS
cord-010027-r0tl01kq	546	15	within	within	IN
cord-010027-r0tl01kq	546	16	arterial	arterial	JJ
cord-010027-r0tl01kq	546	17	specimens	specimen	NNS
cord-010027-r0tl01kq	546	18	.	.	.
cord-010027-r0tl01kq	547	1	Furthermore	furthermore	RB
cord-010027-r0tl01kq	547	2	,	,	,
cord-010027-r0tl01kq	547	3	metric	metric	JJ
cord-010027-r0tl01kq	547	4	data	datum	NNS
cord-010027-r0tl01kq	547	5	generated	generate	VBN
cord-010027-r0tl01kq	547	6	in	in	IN
cord-010027-r0tl01kq	547	7	the	the	DT
cord-010027-r0tl01kq	547	8	process	process	NN
cord-010027-r0tl01kq	547	9	can	can	MD
cord-010027-r0tl01kq	547	10	support	support	VB
cord-010027-r0tl01kq	547	11	the	the	DT
cord-010027-r0tl01kq	547	12	3D	3d	JJ
cord-010027-r0tl01kq	547	13	images	image	NNS
cord-010027-r0tl01kq	547	14	to	to	TO
cord-010027-r0tl01kq	547	15	study	study	VB
cord-010027-r0tl01kq	547	16	the	the	DT
cord-010027-r0tl01kq	547	17	microvasculature	microvasculature	NN
cord-010027-r0tl01kq	547	18	.	.	.
cord-010027-r0tl01kq	548	1	This	this	DT
cord-010027-r0tl01kq	548	2	method	method	NN
cord-010027-r0tl01kq	548	3	will	will	MD
cord-010027-r0tl01kq	548	4	be	be	VB
cord-010027-r0tl01kq	548	5	applied	apply	VBN
cord-010027-r0tl01kq	548	6	to	to	IN
cord-010027-r0tl01kq	548	7	diseased	diseased	JJ
cord-010027-r0tl01kq	548	8	arteries	artery	NNS
cord-010027-r0tl01kq	548	9	in	in	IN
cord-010027-r0tl01kq	548	10	future	future	NN
cord-010027-r0tl01kq	548	11	to	to	TO
cord-010027-r0tl01kq	548	12	generate	generate	VB
cord-010027-r0tl01kq	548	13	novel	novel	JJ
cord-010027-r0tl01kq	548	14	hypotheses	hypothesis	NNS
cord-010027-r0tl01kq	548	15	about	about	IN
cord-010027-r0tl01kq	548	16	the	the	DT
cord-010027-r0tl01kq	548	17	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	548	18	process	process	NN
cord-010027-r0tl01kq	548	19	.	.	.
cord-010027-r0tl01kq	549	1	Acknowledgements	acknowledgement	NNS
cord-010027-r0tl01kq	549	2	:	:	:
cord-010027-r0tl01kq	550	1	This	this	DT
cord-010027-r0tl01kq	550	2	research	research	NN
cord-010027-r0tl01kq	550	3	was	be	VBD
cord-010027-r0tl01kq	550	4	supported	support	VBN
cord-010027-r0tl01kq	550	5	by	by	IN
cord-010027-r0tl01kq	550	6	a	a	DT
cord-010027-r0tl01kq	550	7	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	550	8	intercalated	intercalate	VBN
cord-010027-r0tl01kq	550	9	studentship	studentship	NN
cord-010027-r0tl01kq	550	10	.	.	.
cord-010027-r0tl01kq	551	1	Purpose	purpose	NN
cord-010027-r0tl01kq	551	2	of	of	IN
cord-010027-r0tl01kq	551	3	the	the	DT
cord-010027-r0tl01kq	551	4	Study	study	NN
cord-010027-r0tl01kq	551	5	:	:	:
cord-010027-r0tl01kq	551	6	It	-PRON-	PRP
cord-010027-r0tl01kq	551	7	is	be	VBZ
cord-010027-r0tl01kq	551	8	controversial	controversial	JJ
cord-010027-r0tl01kq	551	9	whether	whether	IN
cord-010027-r0tl01kq	551	10	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	551	11	can	can	MD
cord-010027-r0tl01kq	551	12	be	be	VB
cord-010027-r0tl01kq	551	13	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	551	14	with	with	IN
cord-010027-r0tl01kq	551	15	confidence	confidence	NN
cord-010027-r0tl01kq	551	16	in	in	IN
cord-010027-r0tl01kq	551	17	effusion	effusion	NN
cord-010027-r0tl01kq	551	18	cytology	cytology	NN
cord-010027-r0tl01kq	551	19	and	and	CC
cord-010027-r0tl01kq	551	20	therefore	therefore	RB
cord-010027-r0tl01kq	551	21	an	an	DT
cord-010027-r0tl01kq	551	22	ancillary	ancillary	JJ
cord-010027-r0tl01kq	551	23	marker	marker	NN
cord-010027-r0tl01kq	551	24	of	of	IN
cord-010027-r0tl01kq	551	25	malignant	malignant	JJ
cord-010027-r0tl01kq	551	26	mesothelial	mesothelial	JJ
cord-010027-r0tl01kq	551	27	cells	cell	NNS
cord-010027-r0tl01kq	551	28	would	would	MD
cord-010027-r0tl01kq	551	29	be	be	VB
cord-010027-r0tl01kq	551	30	clinically	clinically	RB
cord-010027-r0tl01kq	551	31	valuable	valuable	JJ
cord-010027-r0tl01kq	551	32	.	.	.
cord-010027-r0tl01kq	552	1	BRCA-1	BRCA-1	NNP
cord-010027-r0tl01kq	552	2	associated	associated	JJ
cord-010027-r0tl01kq	552	3	protein	protein	NN
cord-010027-r0tl01kq	552	4	(	(	-LRB-
cord-010027-r0tl01kq	552	5	BAP1	BAP1	NNP
cord-010027-r0tl01kq	552	6	)	)	-RRB-
cord-010027-r0tl01kq	552	7	is	be	VBZ
cord-010027-r0tl01kq	552	8	a	a	DT
cord-010027-r0tl01kq	552	9	tumour	tumour	NN
cord-010027-r0tl01kq	552	10	suppressor	suppressor	NN
cord-010027-r0tl01kq	552	11	gene	gene	NN
cord-010027-r0tl01kq	552	12	which	which	WDT
cord-010027-r0tl01kq	552	13	shows	show	VBZ
cord-010027-r0tl01kq	552	14	biallelic	biallelic	NN
cord-010027-r0tl01kq	552	15	inactivation	inactivation	NN
cord-010027-r0tl01kq	552	16	in	in	IN
cord-010027-r0tl01kq	552	17	approximately	approximately	RB
cord-010027-r0tl01kq	552	18	half	half	NN
cord-010027-r0tl01kq	552	19	of	of	IN
cord-010027-r0tl01kq	552	20	all	all	DT
cord-010027-r0tl01kq	552	21	mesotheliomas	mesotheliomas	NN
cord-010027-r0tl01kq	552	22	.	.	.
cord-010027-r0tl01kq	553	1	BAP1	BAP1	NNP
cord-010027-r0tl01kq	553	2	expression	expression	NN
cord-010027-r0tl01kq	553	3	is	be	VBZ
cord-010027-r0tl01kq	553	4	commonly	commonly	RB
cord-010027-r0tl01kq	553	5	lost	lose	VBN
cord-010027-r0tl01kq	553	6	in	in	IN
cord-010027-r0tl01kq	553	7	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	553	8	.	.	.
cord-010027-r0tl01kq	554	1	We	-PRON-	PRP
cord-010027-r0tl01kq	554	2	investigated	investigate	VBD
cord-010027-r0tl01kq	554	3	whether	whether	IN
cord-010027-r0tl01kq	554	4	loss	loss	NN
cord-010027-r0tl01kq	554	5	of	of	IN
cord-010027-r0tl01kq	554	6	BAP1	BAP1	NNP
cord-010027-r0tl01kq	554	7	expression	expression	NN
cord-010027-r0tl01kq	554	8	can	can	MD
cord-010027-r0tl01kq	554	9	be	be	VB
cord-010027-r0tl01kq	554	10	used	use	VBN
cord-010027-r0tl01kq	554	11	to	to	TO
cord-010027-r0tl01kq	554	12	support	support	VB
cord-010027-r0tl01kq	554	13	a	a	DT
cord-010027-r0tl01kq	554	14	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	554	15	of	of	IN
cord-010027-r0tl01kq	554	16	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	554	17	in	in	IN
cord-010027-r0tl01kq	554	18	effusion	effusion	NN
cord-010027-r0tl01kq	554	19	cytology	cytology	NN
cord-010027-r0tl01kq	554	20	.	.	.
cord-010027-r0tl01kq	555	1	Methods	method	NNS
cord-010027-r0tl01kq	555	2	:	:	:
cord-010027-r0tl01kq	555	3	Immunohistochemistry	Immunohistochemistry	NNP
cord-010027-r0tl01kq	555	4	(	(	-LRB-
cord-010027-r0tl01kq	555	5	IHC	IHC	NNP
cord-010027-r0tl01kq	555	6	)	)	-RRB-
cord-010027-r0tl01kq	555	7	for	for	IN
cord-010027-r0tl01kq	555	8	BAP1	BAP1	NNP
cord-010027-r0tl01kq	555	9	was	be	VBD
cord-010027-r0tl01kq	555	10	performed	perform	VBN
cord-010027-r0tl01kq	555	11	on	on	IN
cord-010027-r0tl01kq	555	12	cell	cell	NN
cord-010027-r0tl01kq	555	13	blocks	block	NNS
cord-010027-r0tl01kq	555	14	from	from	IN
cord-010027-r0tl01kq	555	15	effusions	effusion	NNS
cord-010027-r0tl01kq	555	16	associated	associate	VBN
cord-010027-r0tl01kq	555	17	with	with	IN
cord-010027-r0tl01kq	555	18	confirmed	confirm	VBN
cord-010027-r0tl01kq	555	19	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	555	20	cases	case	NNS
cord-010027-r0tl01kq	555	21	,	,	,
cord-010027-r0tl01kq	555	22	effusions	effusion	NNS
cord-010027-r0tl01kq	555	23	containing	contain	VBG
cord-010027-r0tl01kq	555	24	mesothelial	mesothelial	JJ
cord-010027-r0tl01kq	555	25	cell	cell	NN
cord-010027-r0tl01kq	555	26	atypia	atypia	NN
cord-010027-r0tl01kq	555	27	,	,	,
cord-010027-r0tl01kq	555	28	benign	benign	JJ
cord-010027-r0tl01kq	555	29	effusions	effusion	NNS
cord-010027-r0tl01kq	555	30	,	,	,
cord-010027-r0tl01kq	555	31	and	and	CC
cord-010027-r0tl01kq	555	32	effusions	effusion	NNS
cord-010027-r0tl01kq	555	33	from	from	IN
cord-010027-r0tl01kq	555	34	patients	patient	NNS
cord-010027-r0tl01kq	555	35	with	with	IN
cord-010027-r0tl01kq	555	36	lung	lung	NN
cord-010027-r0tl01kq	555	37	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	555	38	.	.	.
cord-010027-r0tl01kq	556	1	Results	result	NNS
cord-010027-r0tl01kq	556	2	:	:	:
cord-010027-r0tl01kq	556	3	IHC	IHC	NNP
cord-010027-r0tl01kq	556	4	for	for	IN
cord-010027-r0tl01kq	556	5	BAP1	BAP1	NNP
cord-010027-r0tl01kq	556	6	was	be	VBD
cord-010027-r0tl01kq	556	7	performed	perform	VBN
cord-010027-r0tl01kq	556	8	on	on	IN
cord-010027-r0tl01kq	556	9	75	75	CD
cord-010027-r0tl01kq	556	10	cases	case	NNS
cord-010027-r0tl01kq	556	11	of	of	IN
cord-010027-r0tl01kq	556	12	confirmed	confirm	VBN
cord-010027-r0tl01kq	556	13	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	556	14	.	.	.
cord-010027-r0tl01kq	557	1	43	43	CD
cord-010027-r0tl01kq	557	2	(	(	-LRB-
cord-010027-r0tl01kq	557	3	57.3	57.3	CD
cord-010027-r0tl01kq	557	4	%	%	NN
cord-010027-r0tl01kq	557	5	)	)	-RRB-
cord-010027-r0tl01kq	557	6	showed	show	VBD
cord-010027-r0tl01kq	557	7	negative	negative	JJ
cord-010027-r0tl01kq	557	8	staining	staining	NN
cord-010027-r0tl01kq	557	9	in	in	IN
cord-010027-r0tl01kq	557	10	the	the	DT
cord-010027-r0tl01kq	557	11	presence	presence	NN
cord-010027-r0tl01kq	557	12	of	of	IN
cord-010027-r0tl01kq	557	13	an	an	DT
cord-010027-r0tl01kq	557	14	internal	internal	JJ
cord-010027-r0tl01kq	557	15	positive	positive	JJ
cord-010027-r0tl01kq	557	16	control	control	NN
cord-010027-r0tl01kq	557	17	.	.	.
cord-010027-r0tl01kq	558	1	In	in	IN
cord-010027-r0tl01kq	558	2	57	57	CD
cord-010027-r0tl01kq	558	3	effusions	effusion	NNS
cord-010027-r0tl01kq	558	4	considered	consider	VBN
cord-010027-r0tl01kq	558	5	to	to	TO
cord-010027-r0tl01kq	558	6	have	have	VB
cord-010027-r0tl01kq	558	7	atypical	atypical	JJ
cord-010027-r0tl01kq	558	8	mesothelial	mesothelial	JJ
cord-010027-r0tl01kq	558	9	cells	cell	NNS
cord-010027-r0tl01kq	558	10	in	in	IN
cord-010027-r0tl01kq	558	11	the	the	DT
cord-010027-r0tl01kq	558	12	absence	absence	NN
cord-010027-r0tl01kq	558	13	of	of	IN
cord-010027-r0tl01kq	558	14	definitive	definitive	JJ
cord-010027-r0tl01kq	558	15	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	558	16	of	of	IN
cord-010027-r0tl01kq	558	17	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	558	18	,	,	,
cord-010027-r0tl01kq	558	19	8	8	CD
cord-010027-r0tl01kq	558	20	cases	case	NNS
cord-010027-r0tl01kq	558	21	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	558	22	negative	negative	JJ
cord-010027-r0tl01kq	558	23	staining	staining	NN
cord-010027-r0tl01kq	558	24	for	for	IN
cord-010027-r0tl01kq	558	25	BAP1	BAP1	NNP
cord-010027-r0tl01kq	558	26	.	.	.
cord-010027-r0tl01kq	559	1	On	on	IN
cord-010027-r0tl01kq	559	2	follow	follow	NN
cord-010027-r0tl01kq	559	3	up	up	RP
cord-010027-r0tl01kq	559	4	,	,	,
cord-010027-r0tl01kq	559	5	6	6	CD
cord-010027-r0tl01kq	559	6	of	of	IN
cord-010027-r0tl01kq	559	7	these	these	DT
cord-010027-r0tl01kq	559	8	patients	patient	NNS
cord-010027-r0tl01kq	559	9	received	receive	VBD
cord-010027-r0tl01kq	559	10	a	a	DT
cord-010027-r0tl01kq	559	11	definitive	definitive	JJ
cord-010027-r0tl01kq	559	12	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	559	13	of	of	IN
cord-010027-r0tl01kq	559	14	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	559	15	in	in	IN
cord-010027-r0tl01kq	559	16	the	the	DT
cord-010027-r0tl01kq	559	17	subsequent	subsequent	JJ
cord-010027-r0tl01kq	559	18	14	14	CD
cord-010027-r0tl01kq	559	19	months	month	NNS
cord-010027-r0tl01kq	559	20	(	(	-LRB-
cord-010027-r0tl01kq	559	21	2	2	CD
cord-010027-r0tl01kq	559	22	were	be	VBD
cord-010027-r0tl01kq	559	23	lost	lose	VBN
cord-010027-r0tl01kq	559	24	to	to	TO
cord-010027-r0tl01kq	559	25	follow	follow	VB
cord-010027-r0tl01kq	559	26	up	up	RP
cord-010027-r0tl01kq	559	27	immediately	immediately	RB
cord-010027-r0tl01kq	559	28	)	)	-RRB-
cord-010027-r0tl01kq	559	29	.	.	.
cord-010027-r0tl01kq	560	1	Only	only	RB
cord-010027-r0tl01kq	560	2	5	5	CD
cord-010027-r0tl01kq	560	3	of	of	IN
cord-010027-r0tl01kq	560	4	100	100	CD
cord-010027-r0tl01kq	560	5	consecutive	consecutive	JJ
cord-010027-r0tl01kq	560	6	benign	benign	JJ
cord-010027-r0tl01kq	560	7	effusions	effusion	NNS
cord-010027-r0tl01kq	560	8	were	be	VBD
cord-010027-r0tl01kq	560	9	interpreted	interpret	VBN
cord-010027-r0tl01kq	560	10	as	as	IN
cord-010027-r0tl01kq	560	11	BAP1	BAP1	NNP
cord-010027-r0tl01kq	560	12	negative	negative	JJ
cord-010027-r0tl01kq	560	13	.	.	.
cord-010027-r0tl01kq	561	1	47	47	CD
cord-010027-r0tl01kq	561	2	patients	patient	NNS
cord-010027-r0tl01kq	561	3	with	with	IN
cord-010027-r0tl01kq	561	4	confirmed	confirm	VBN
cord-010027-r0tl01kq	561	5	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	561	6	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	561	7	positive	positive	JJ
cord-010027-r0tl01kq	561	8	staining	staining	NN
cord-010027-r0tl01kq	561	9	for	for	IN
cord-010027-r0tl01kq	561	10	BAP1	BAP1	NNP
cord-010027-r0tl01kq	561	11	.	.	.
cord-010027-r0tl01kq	562	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	562	2	:	:	:
cord-010027-r0tl01kq	563	1	We	-PRON-	PRP
cord-010027-r0tl01kq	563	2	conclude	conclude	VBP
cord-010027-r0tl01kq	563	3	that	that	IN
cord-010027-r0tl01kq	563	4	loss	loss	NN
cord-010027-r0tl01kq	563	5	of	of	IN
cord-010027-r0tl01kq	563	6	BAP1	BAP1	NNP
cord-010027-r0tl01kq	563	7	expression	expression	NN
cord-010027-r0tl01kq	563	8	in	in	IN
cord-010027-r0tl01kq	563	9	effusion	effusion	NN
cord-010027-r0tl01kq	563	10	cytology	cytology	NN
cord-010027-r0tl01kq	563	11	is	be	VBZ
cord-010027-r0tl01kq	563	12	quite	quite	RB
cord-010027-r0tl01kq	563	13	specific	specific	JJ
cord-010027-r0tl01kq	563	14	for	for	IN
cord-010027-r0tl01kq	563	15	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	563	16	.	.	.
cord-010027-r0tl01kq	564	1	Whilst	whilst	IN
cord-010027-r0tl01kq	564	2	it	-PRON-	PRP
cord-010027-r0tl01kq	564	3	is	be	VBZ
cord-010027-r0tl01kq	564	4	not	not	RB
cord-010027-r0tl01kq	564	5	definitive	definitive	JJ
cord-010027-r0tl01kq	564	6	,	,	,
cord-010027-r0tl01kq	564	7	it	-PRON-	PRP
cord-010027-r0tl01kq	564	8	can	can	MD
cord-010027-r0tl01kq	564	9	be	be	VB
cord-010027-r0tl01kq	564	10	used	use	VBN
cord-010027-r0tl01kq	564	11	to	to	TO
cord-010027-r0tl01kq	564	12	support	support	VB
cord-010027-r0tl01kq	564	13	the	the	DT
cord-010027-r0tl01kq	564	14	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	564	15	of	of	IN
cord-010027-r0tl01kq	564	16	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	564	17	in	in	IN
cord-010027-r0tl01kq	564	18	atypical	atypical	JJ
cord-010027-r0tl01kq	564	19	effusions	effusion	NNS
cord-010027-r0tl01kq	564	20	.	.	.
cord-010027-r0tl01kq	565	1	We	-PRON-	PRP
cord-010027-r0tl01kq	565	2	caution	caution	VBP
cord-010027-r0tl01kq	565	3	that	that	DT
cord-010027-r0tl01kq	565	4	interpretation	interpretation	NN
cord-010027-r0tl01kq	565	5	of	of	IN
cord-010027-r0tl01kq	565	6	BAP1	BAP1	NNP
cord-010027-r0tl01kq	565	7	IHC	IHC	NNP
cord-010027-r0tl01kq	565	8	on	on	IN
cord-010027-r0tl01kq	565	9	cell	cell	NN
cord-010027-r0tl01kq	565	10	block	block	NN
cord-010027-r0tl01kq	565	11	may	may	MD
cord-010027-r0tl01kq	565	12	be	be	VB
cord-010027-r0tl01kq	565	13	difficult	difficult	JJ
cord-010027-r0tl01kq	565	14	and	and	CC
cord-010027-r0tl01kq	565	15	that	that	IN
cord-010027-r0tl01kq	565	16	convincing	convincing	JJ
cord-010027-r0tl01kq	565	17	positive	positive	JJ
cord-010027-r0tl01kq	565	18	staining	staining	NN
cord-010027-r0tl01kq	565	19	in	in	IN
cord-010027-r0tl01kq	565	20	non	non	JJ
cord-010027-r0tl01kq	565	21	-	-	JJ
cord-010027-r0tl01kq	565	22	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	565	23	cells	cell	NNS
cord-010027-r0tl01kq	565	24	is	be	VBZ
cord-010027-r0tl01kq	565	25	required	require	VBN
cord-010027-r0tl01kq	565	26	before	before	IN
cord-010027-r0tl01kq	565	27	atypical	atypical	JJ
cord-010027-r0tl01kq	565	28	cells	cell	NNS
cord-010027-r0tl01kq	565	29	are	be	VBP
cord-010027-r0tl01kq	565	30	considered	consider	VBN
cord-010027-r0tl01kq	565	31	negative	negative	JJ
cord-010027-r0tl01kq	565	32	.	.	.
cord-010027-r0tl01kq	566	1	We	-PRON-	PRP
cord-010027-r0tl01kq	566	2	also	also	RB
cord-010027-r0tl01kq	566	3	note	note	VBP
cord-010027-r0tl01kq	566	4	that	that	IN
cord-010027-r0tl01kq	566	5	BAP1	BAP1	NNP
cord-010027-r0tl01kq	566	6	loss	loss	NN
cord-010027-r0tl01kq	566	7	is	be	VBZ
cord-010027-r0tl01kq	566	8	not	not	RB
cord-010027-r0tl01kq	566	9	a	a	DT
cord-010027-r0tl01kq	566	10	sensitive	sensitive	JJ
cord-010027-r0tl01kq	566	11	test	test	NN
cord-010027-r0tl01kq	566	12	and	and	CC
cord-010027-r0tl01kq	566	13	can	can	MD
cord-010027-r0tl01kq	566	14	not	not	RB
cord-010027-r0tl01kq	566	15	be	be	VB
cord-010027-r0tl01kq	566	16	used	use	VBN
cord-010027-r0tl01kq	566	17	to	to	TO
cord-010027-r0tl01kq	566	18	exclude	exclude	VB
cord-010027-r0tl01kq	566	19	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	566	20	.	.	.
cord-010027-r0tl01kq	567	1	The	the	DT
cord-010027-r0tl01kq	567	2	South	South	NNP
cord-010027-r0tl01kq	567	3	-	-	HYPH
cord-010027-r0tl01kq	567	4	East	East	NNP
cord-010027-r0tl01kq	567	5	of	of	IN
cord-010027-r0tl01kq	567	6	Scotland	Scotland	NNP
cord-010027-r0tl01kq	567	7	Experience	Experience	NNP
cord-010027-r0tl01kq	567	8	on	on	IN
cord-010027-r0tl01kq	567	9	the	the	DT
cord-010027-r0tl01kq	567	10	Molecular	Molecular	NNP
cord-010027-r0tl01kq	567	11	Detection	Detection	NNP
cord-010027-r0tl01kq	567	12	of	of	IN
cord-010027-r0tl01kq	567	13	EGFR	EGFR	NNP
cord-010027-r0tl01kq	567	14	,	,	,
cord-010027-r0tl01kq	567	15	KRAS	KRAS	NNP
cord-010027-r0tl01kq	567	16	and	and	CC
cord-010027-r0tl01kq	567	17	ALK	ALK	NNP
cord-010027-r0tl01kq	567	18	Mutations	Mutations	NNPS
cord-010027-r0tl01kq	567	19	in	in	IN
cord-010027-r0tl01kq	567	20	Lung	Lung	NNP
cord-010027-r0tl01kq	567	21	Adenocarcinomas	Adenocarcinomas	NNP
cord-010027-r0tl01kq	567	22	P	P	NNP
cord-010027-r0tl01kq	567	23	Y	Y	NNP
cord-010027-r0tl01kq	567	24	Kheng	Kheng	NNP
cord-010027-r0tl01kq	567	25	1	1	CD
cord-010027-r0tl01kq	567	26	;	;	:
cord-010027-r0tl01kq	567	27	L	L	NNP
cord-010027-r0tl01kq	567	28	Williams	Williams	NNP
cord-010027-r0tl01kq	567	29	2	2	CD
cord-010027-r0tl01kq	567	30	;	;	:
cord-010027-r0tl01kq	567	31	K	K	NNP
cord-010027-r0tl01kq	567	32	Walsh	Walsh	NNP
cord-010027-r0tl01kq	567	33	1	1	CD
cord-010027-r0tl01kq	567	34	;	;	:
cord-010027-r0tl01kq	567	35	J	J	NNP
cord-010027-r0tl01kq	567	36	Fairley	Fairley	NNP
cord-010027-r0tl01kq	567	37	1	1	CD
cord-010027-r0tl01kq	567	38	;	;	:
cord-010027-r0tl01kq	567	39	S	S	NNP
cord-010027-r0tl01kq	567	40	Camus	Camus	NNP
cord-010027-r0tl01kq	567	41	1	1	CD
cord-010027-r0tl01kq	567	42	;	;	:
cord-010027-r0tl01kq	567	43	L	L	NNP
cord-010027-r0tl01kq	567	44	Gilroy	Gilroy	NNP
cord-010027-r0tl01kq	567	45	1	1	CD
cord-010027-r0tl01kq	567	46	;	;	:
cord-010027-r0tl01kq	567	47	K	K	NNP
cord-010027-r0tl01kq	567	48	Gilmour	Gilmour	NNP
cord-010027-r0tl01kq	567	49	1	1	CD
cord-010027-r0tl01kq	567	50	;	;	:
cord-010027-r0tl01kq	567	51	D	D	NNP
cord-010027-r0tl01kq	567	52	Stirling	Stirling	NNP
cord-010027-r0tl01kq	567	53	1	1	CD
cord-010027-r0tl01kq	567	54	;	;	:
cord-010027-r0tl01kq	567	55	W	W	NNP
cord-010027-r0tl01kq	567	56	Wallace	Wallace	NNP
cord-010027-r0tl01kq	567	57	1	1	CD
cord-010027-r0tl01kq	567	58	;	;	:
cord-010027-r0tl01kq	567	59	D	D	NNP
cord-010027-r0tl01kq	567	60	Harrison	Harrison	NNP
cord-010027-r0tl01kq	567	61	1	1	CD
cord-010027-r0tl01kq	567	62	;	;	:
cord-010027-r0tl01kq	568	1	A	a	DT
cord-010027-r0tl01kq	568	2	Oniscu	Oniscu	NNP
cord-010027-r0tl01kq	568	3	1	1	CD
cord-010027-r0tl01kq	568	4	1	1	CD
cord-010027-r0tl01kq	568	5	Royal	Royal	NNP
cord-010027-r0tl01kq	568	6	Infirmary	Infirmary	NNP
cord-010027-r0tl01kq	568	7	of	of	IN
cord-010027-r0tl01kq	568	8	Edinburgh	Edinburgh	NNP
cord-010027-r0tl01kq	568	9	,	,	,
cord-010027-r0tl01kq	568	10	Edinburgh	Edinburgh	NNP
cord-010027-r0tl01kq	568	11	,	,	,
cord-010027-r0tl01kq	568	12	UK	UK	NNP
cord-010027-r0tl01kq	568	13	;	;	:
cord-010027-r0tl01kq	568	14	2	2	LS
cord-010027-r0tl01kq	568	15	The	the	DT
cord-010027-r0tl01kq	568	16	University	University	NNP
cord-010027-r0tl01kq	568	17	of	of	IN
cord-010027-r0tl01kq	568	18	Edinburgh	Edinburgh	NNP
cord-010027-r0tl01kq	568	19	,	,	,
cord-010027-r0tl01kq	568	20	Edinburgh	Edinburgh	NNP
cord-010027-r0tl01kq	568	21	,	,	,
cord-010027-r0tl01kq	568	22	UK	UK	NNP
cord-010027-r0tl01kq	569	1	The	the	DT
cord-010027-r0tl01kq	569	2	approval	approval	NN
cord-010027-r0tl01kq	569	3	of	of	IN
cord-010027-r0tl01kq	569	4	novel	novel	NN
cord-010027-r0tl01kq	569	5	targeted	target	VBN
cord-010027-r0tl01kq	569	6	treatments	treatment	NNS
cord-010027-r0tl01kq	569	7	for	for	IN
cord-010027-r0tl01kq	569	8	EGFR	egfr	NN
cord-010027-r0tl01kq	569	9	-	-	HYPH
cord-010027-r0tl01kq	569	10	positive	positive	JJ
cord-010027-r0tl01kq	569	11	and	and	CC
cord-010027-r0tl01kq	569	12	ALK	alk	NN
cord-010027-r0tl01kq	569	13	-	-	HYPH
cord-010027-r0tl01kq	569	14	positive	positive	JJ
cord-010027-r0tl01kq	569	15	non	non	JJ
cord-010027-r0tl01kq	569	16	-	-	JJ
cord-010027-r0tl01kq	569	17	small	small	JJ
cord-010027-r0tl01kq	569	18	cell	cell	NN
cord-010027-r0tl01kq	569	19	lung	lung	NN
cord-010027-r0tl01kq	569	20	cancer	cancer	NN
cord-010027-r0tl01kq	569	21	(	(	-LRB-
cord-010027-r0tl01kq	569	22	NSCLC	NSCLC	NNP
cord-010027-r0tl01kq	569	23	)	)	-RRB-
cord-010027-r0tl01kq	569	24	has	have	VBZ
cord-010027-r0tl01kq	569	25	led	lead	VBN
cord-010027-r0tl01kq	569	26	to	to	IN
cord-010027-r0tl01kq	569	27	the	the	DT
cord-010027-r0tl01kq	569	28	increased	increase	VBN
cord-010027-r0tl01kq	569	29	requirement	requirement	NN
cord-010027-r0tl01kq	569	30	for	for	IN
cord-010027-r0tl01kq	569	31	mutation	mutation	NN
cord-010027-r0tl01kq	569	32	testing	testing	NN
cord-010027-r0tl01kq	569	33	services	service	NNS
cord-010027-r0tl01kq	569	34	in	in	IN
cord-010027-r0tl01kq	569	35	South	South	NNP
cord-010027-r0tl01kq	569	36	East	East	NNP
cord-010027-r0tl01kq	569	37	of	of	IN
cord-010027-r0tl01kq	569	38	Scotland	Scotland	NNP
cord-010027-r0tl01kq	569	39	.	.	.
cord-010027-r0tl01kq	570	1	EGFR	EGFR	NNP
cord-010027-r0tl01kq	570	2	mutations	mutation	NNS
cord-010027-r0tl01kq	570	3	are	be	VBP
cord-010027-r0tl01kq	570	4	typically	typically	RB
cord-010027-r0tl01kq	570	5	found	find	VBN
cord-010027-r0tl01kq	570	6	in	in	IN
cord-010027-r0tl01kq	570	7	females	female	NNS
cord-010027-r0tl01kq	570	8	,	,	,
cord-010027-r0tl01kq	570	9	Asians	Asians	NNPS
cord-010027-r0tl01kq	570	10	and	and	CC
cord-010027-r0tl01kq	570	11	never	never	RB
cord-010027-r0tl01kq	570	12	smokers	smoker	NNS
cord-010027-r0tl01kq	570	13	whereas	whereas	IN
cord-010027-r0tl01kq	570	14	KRAS	kra	NNS
cord-010027-r0tl01kq	570	15	mutations	mutation	NNS
cord-010027-r0tl01kq	570	16	are	be	VBP
cord-010027-r0tl01kq	570	17	associated	associate	VBN
cord-010027-r0tl01kq	570	18	with	with	IN
cord-010027-r0tl01kq	570	19	smoking	smoking	NN
cord-010027-r0tl01kq	570	20	.	.	.
cord-010027-r0tl01kq	571	1	ALK	ALK	NNP
cord-010027-r0tl01kq	571	2	rearrangements	rearrangement	NNS
cord-010027-r0tl01kq	571	3	are	be	VBP
cord-010027-r0tl01kq	571	4	commonly	commonly	RB
cord-010027-r0tl01kq	571	5	found	find	VBN
cord-010027-r0tl01kq	571	6	in	in	IN
cord-010027-r0tl01kq	571	7	younger	young	JJR
cord-010027-r0tl01kq	571	8	patients	patient	NNS
cord-010027-r0tl01kq	571	9	and	and	CC
cord-010027-r0tl01kq	571	10	never	never	RB
cord-010027-r0tl01kq	571	11	smokers	smoker	NNS
cord-010027-r0tl01kq	571	12	.	.	.
cord-010027-r0tl01kq	572	1	This	this	DT
cord-010027-r0tl01kq	572	2	study	study	NN
cord-010027-r0tl01kq	572	3	aimed	aim	VBD
cord-010027-r0tl01kq	572	4	to	to	TO
cord-010027-r0tl01kq	572	5	determine	determine	VB
cord-010027-r0tl01kq	572	6	the	the	DT
cord-010027-r0tl01kq	572	7	prevalence	prevalence	NN
cord-010027-r0tl01kq	572	8	of	of	IN
cord-010027-r0tl01kq	572	9	EGFR	EGFR	NNP
cord-010027-r0tl01kq	572	10	,	,	,
cord-010027-r0tl01kq	572	11	KRAS	KRAS	NNP
cord-010027-r0tl01kq	572	12	and	and	CC
cord-010027-r0tl01kq	572	13	ALK	ALK	NNP
cord-010027-r0tl01kq	572	14	mutations	mutation	NNS
cord-010027-r0tl01kq	572	15	in	in	IN
cord-010027-r0tl01kq	572	16	South	South	NNP
cord-010027-r0tl01kq	572	17	East	East	NNP
cord-010027-r0tl01kq	572	18	of	of	IN
cord-010027-r0tl01kq	572	19	Scotland	Scotland	NNP
cord-010027-r0tl01kq	572	20	and	and	CC
cord-010027-r0tl01kq	572	21	to	to	TO
cord-010027-r0tl01kq	572	22	evaluate	evaluate	VB
cord-010027-r0tl01kq	572	23	our	-PRON-	PRP$
cord-010027-r0tl01kq	572	24	experience	experience	NN
cord-010027-r0tl01kq	572	25	in	in	IN
cord-010027-r0tl01kq	572	26	testing	testing	NN
cord-010027-r0tl01kq	572	27	of	of	IN
cord-010027-r0tl01kq	572	28	ALK	ALK	NNP
cord-010027-r0tl01kq	572	29	with	with	IN
cord-010027-r0tl01kq	572	30	IHC	IHC	NNP
cord-010027-r0tl01kq	572	31	and	and	CC
cord-010027-r0tl01kq	572	32	FISH	fish	NN
cord-010027-r0tl01kq	572	33	.	.	.
cord-010027-r0tl01kq	573	1	Data	datum	NNS
cord-010027-r0tl01kq	573	2	of	of	IN
cord-010027-r0tl01kq	573	3	all	all	DT
cord-010027-r0tl01kq	573	4	patients	patient	NNS
cord-010027-r0tl01kq	573	5	tested	test	VBN
cord-010027-r0tl01kq	573	6	were	be	VBD
cord-010027-r0tl01kq	573	7	collected	collect	VBN
cord-010027-r0tl01kq	573	8	retrospectively	retrospectively	RB
cord-010027-r0tl01kq	573	9	from	from	IN
cord-010027-r0tl01kq	573	10	clinical	clinical	JJ
cord-010027-r0tl01kq	573	11	records	record	NNS
cord-010027-r0tl01kq	573	12	.	.	.
cord-010027-r0tl01kq	574	1	From	from	IN
cord-010027-r0tl01kq	574	2	January	January	NNP
cord-010027-r0tl01kq	574	3	2011	2011	CD
cord-010027-r0tl01kq	574	4	to	to	IN
cord-010027-r0tl01kq	574	5	May	May	NNP
cord-010027-r0tl01kq	574	6	2014	2014	CD
cord-010027-r0tl01kq	574	7	,	,	,
cord-010027-r0tl01kq	574	8	we	-PRON-	PRP
cord-010027-r0tl01kq	574	9	reported	report	VBD
cord-010027-r0tl01kq	574	10	mutation	mutation	NN
cord-010027-r0tl01kq	574	11	rates	rate	NNS
cord-010027-r0tl01kq	574	12	of	of	IN
cord-010027-r0tl01kq	574	13	EGFR	EGFR	NNP
cord-010027-r0tl01kq	574	14	,	,	,
cord-010027-r0tl01kq	574	15	KRAS	KRAS	NNP
cord-010027-r0tl01kq	574	16	and	and	CC
cord-010027-r0tl01kq	574	17	ALK	ALK	NNP
cord-010027-r0tl01kq	574	18	to	to	TO
cord-010027-r0tl01kq	574	19	be	be	VB
cord-010027-r0tl01kq	574	20	10.4	10.4	CD
cord-010027-r0tl01kq	574	21	%	%	NN
cord-010027-r0tl01kq	574	22	(	(	-LRB-
cord-010027-r0tl01kq	574	23	67/643	67/643	CD
cord-010027-r0tl01kq	574	24	)	)	-RRB-
cord-010027-r0tl01kq	574	25	,	,	,
cord-010027-r0tl01kq	574	26	35.8	35.8	CD
cord-010027-r0tl01kq	574	27	%	%	NN
cord-010027-r0tl01kq	574	28	(	(	-LRB-
cord-010027-r0tl01kq	574	29	86/240	86/240	CD
cord-010027-r0tl01kq	574	30	)	)	-RRB-
cord-010027-r0tl01kq	574	31	and	and	CC
cord-010027-r0tl01kq	574	32	2.3	2.3	CD
cord-010027-r0tl01kq	574	33	%	%	NN
cord-010027-r0tl01kq	574	34	(	(	-LRB-
cord-010027-r0tl01kq	574	35	7/304	7/304	CD
cord-010027-r0tl01kq	574	36	)	)	-RRB-
cord-010027-r0tl01kq	574	37	respectively	respectively	RB
cord-010027-r0tl01kq	574	38	.	.	.
cord-010027-r0tl01kq	575	1	In	in	IN
cord-010027-r0tl01kq	575	2	our	-PRON-	PRP$
cord-010027-r0tl01kq	575	3	cohort	cohort	NN
cord-010027-r0tl01kq	575	4	,	,	,
cord-010027-r0tl01kq	575	5	an	an	DT
cord-010027-r0tl01kq	575	6	increase	increase	NN
cord-010027-r0tl01kq	575	7	in	in	IN
cord-010027-r0tl01kq	575	8	one	one	CD
cord-010027-r0tl01kq	575	9	pack	pack	NN
cord-010027-r0tl01kq	575	10	years	year	NNS
cord-010027-r0tl01kq	575	11	of	of	IN
cord-010027-r0tl01kq	575	12	smoking	smoking	NN
cord-010027-r0tl01kq	575	13	resulted	result	VBD
cord-010027-r0tl01kq	575	14	in	in	IN
cord-010027-r0tl01kq	575	15	a	a	DT
cord-010027-r0tl01kq	575	16	decrease	decrease	NN
cord-010027-r0tl01kq	575	17	in	in	IN
cord-010027-r0tl01kq	575	18	the	the	DT
cord-010027-r0tl01kq	575	19	odds	odd	NNS
cord-010027-r0tl01kq	575	20	ratio	ratio	NN
cord-010027-r0tl01kq	575	21	of	of	IN
cord-010027-r0tl01kq	575	22	EGFR	egfr	NN
cord-010027-r0tl01kq	575	23	-	-	HYPH
cord-010027-r0tl01kq	575	24	positivity	positivity	NN
cord-010027-r0tl01kq	575	25	(	(	-LRB-
cord-010027-r0tl01kq	575	26	OR	or	CC
cord-010027-r0tl01kq	575	27	0.94	0.94	CD
cord-010027-r0tl01kq	575	28	,	,	,
cord-010027-r0tl01kq	575	29	95	95	CD
cord-010027-r0tl01kq	575	30	%	%	NN
cord-010027-r0tl01kq	575	31	CI	CI	NNP
cord-010027-r0tl01kq	575	32	0.92	0.92	CD
cord-010027-r0tl01kq	575	33	-0.96	-0.96	CD
cord-010027-r0tl01kq	575	34	,	,	,
cord-010027-r0tl01kq	575	35	p<0.001	p<0.001	CD
cord-010027-r0tl01kq	575	36	)	)	-RRB-
cord-010027-r0tl01kq	575	37	.	.	.
cord-010027-r0tl01kq	576	1	KRAS	kra	NNS
cord-010027-r0tl01kq	576	2	-	-	HYPH
cord-010027-r0tl01kq	576	3	positivity	positivity	NN
cord-010027-r0tl01kq	576	4	was	be	VBD
cord-010027-r0tl01kq	576	5	associated	associate	VBN
cord-010027-r0tl01kq	576	6	with	with	IN
cord-010027-r0tl01kq	576	7	a	a	DT
cord-010027-r0tl01kq	576	8	history	history	NN
cord-010027-r0tl01kq	576	9	of	of	IN
cord-010027-r0tl01kq	576	10	smoking	smoking	NN
cord-010027-r0tl01kq	576	11	,	,	,
cord-010027-r0tl01kq	576	12	with	with	IN
cord-010027-r0tl01kq	576	13	rates	rate	NNS
cord-010027-r0tl01kq	576	14	in	in	IN
cord-010027-r0tl01kq	576	15	both	both	DT
cord-010027-r0tl01kq	576	16	former	former	JJ
cord-010027-r0tl01kq	576	17	(	(	-LRB-
cord-010027-r0tl01kq	576	18	OR	or	CC
cord-010027-r0tl01kq	576	19	6.26	6.26	CD
cord-010027-r0tl01kq	576	20	,	,	,
cord-010027-r0tl01kq	576	21	95	95	CD
cord-010027-r0tl01kq	576	22	%	%	NN
cord-010027-r0tl01kq	576	23	CI	CI	NNP
cord-010027-r0tl01kq	576	24	2.00	2.00	CD
cord-010027-r0tl01kq	576	25	-	-	SYM
cord-010027-r0tl01kq	576	26	19.56	19.56	CD
cord-010027-r0tl01kq	576	27	,	,	,
cord-010027-r0tl01kq	576	28	p=0.002	p=0.002	NNP
cord-010027-r0tl01kq	576	29	)	)	-RRB-
cord-010027-r0tl01kq	576	30	and	and	CC
cord-010027-r0tl01kq	576	31	current	current	JJ
cord-010027-r0tl01kq	576	32	smokers	smoker	NNS
cord-010027-r0tl01kq	576	33	(	(	-LRB-
cord-010027-r0tl01kq	576	34	OR	or	CC
cord-010027-r0tl01kq	576	35	6.82	6.82	CD
cord-010027-r0tl01kq	576	36	,	,	,
cord-010027-r0tl01kq	576	37	95	95	CD
cord-010027-r0tl01kq	576	38	%	%	NN
cord-010027-r0tl01kq	576	39	CI	CI	NNP
cord-010027-r0tl01kq	576	40	2.18	2.18	CD
cord-010027-r0tl01kq	576	41	-	-	HYPH
cord-010027-r0tl01kq	576	42	21.35	21.35	CD
cord-010027-r0tl01kq	576	43	,	,	,
cord-010027-r0tl01kq	576	44	p=0.001	p=0.001	NNP
cord-010027-r0tl01kq	576	45	)	)	-RRB-
cord-010027-r0tl01kq	576	46	significantly	significantly	RB
cord-010027-r0tl01kq	576	47	higher	high	JJR
cord-010027-r0tl01kq	576	48	than	than	IN
cord-010027-r0tl01kq	576	49	in	in	IN
cord-010027-r0tl01kq	576	50	non	non	JJ
cord-010027-r0tl01kq	576	51	-	-	NNS
cord-010027-r0tl01kq	576	52	smokers	smoker	NNS
cord-010027-r0tl01kq	576	53	.	.	.
cord-010027-r0tl01kq	577	1	The	the	DT
cord-010027-r0tl01kq	577	2	number	number	NN
cord-010027-r0tl01kq	577	3	of	of	IN
cord-010027-r0tl01kq	577	4	smoking	smoke	VBG
cord-010027-r0tl01kq	577	5	pack	pack	NN
cord-010027-r0tl01kq	577	6	years	year	NNS
cord-010027-r0tl01kq	577	7	had	have	VBD
cord-010027-r0tl01kq	577	8	no	no	DT
cord-010027-r0tl01kq	577	9	influence	influence	NN
cord-010027-r0tl01kq	577	10	on	on	IN
cord-010027-r0tl01kq	577	11	the	the	DT
cord-010027-r0tl01kq	577	12	rates	rate	NNS
cord-010027-r0tl01kq	577	13	of	of	IN
cord-010027-r0tl01kq	577	14	KRAS	kra	NNS
cord-010027-r0tl01kq	577	15	-	-	HYPH
cord-010027-r0tl01kq	577	16	positivity	positivity	NN
cord-010027-r0tl01kq	577	17	.	.	.
cord-010027-r0tl01kq	578	1	ALK	ALK	NNP
cord-010027-r0tl01kq	578	2	-	-	HYPH
cord-010027-r0tl01kq	578	3	rearrangements	rearrangement	NNS
cord-010027-r0tl01kq	578	4	were	be	VBD
cord-010027-r0tl01kq	578	5	found	find	VBN
cord-010027-r0tl01kq	578	6	to	to	TO
cord-010027-r0tl01kq	578	7	be	be	VB
cord-010027-r0tl01kq	578	8	associated	associate	VBN
cord-010027-r0tl01kq	578	9	with	with	IN
cord-010027-r0tl01kq	578	10	never	never	RB
cord-010027-r0tl01kq	578	11	smokers	smoker	NNS
cord-010027-r0tl01kq	578	12	(	(	-LRB-
cord-010027-r0tl01kq	578	13	p<0.001	p<0.001	CD
cord-010027-r0tl01kq	578	14	)	)	-RRB-
cord-010027-r0tl01kq	578	15	and	and	CC
cord-010027-r0tl01kq	578	16	younger	young	JJR
cord-010027-r0tl01kq	578	17	patients	patient	NNS
cord-010027-r0tl01kq	578	18	(	(	-LRB-
cord-010027-r0tl01kq	578	19	≤50	≤50	NN
cord-010027-r0tl01kq	578	20	years	year	NNS
cord-010027-r0tl01kq	578	21	old	old	JJ
cord-010027-r0tl01kq	578	22	)	)	-RRB-
cord-010027-r0tl01kq	578	23	(	(	-LRB-
cord-010027-r0tl01kq	578	24	p<0.001	p<0.001	CD
cord-010027-r0tl01kq	578	25	)	)	-RRB-
cord-010027-r0tl01kq	578	26	.	.	.
cord-010027-r0tl01kq	579	1	To	to	IN
cord-010027-r0tl01kq	579	2	date	date	NN
cord-010027-r0tl01kq	579	3	,	,	,
cord-010027-r0tl01kq	579	4	no	no	DT
cord-010027-r0tl01kq	579	5	false	false	JJ
cord-010027-r0tl01kq	579	6	positives	positive	NNS
cord-010027-r0tl01kq	579	7	were	be	VBD
cord-010027-r0tl01kq	579	8	reported	report	VBN
cord-010027-r0tl01kq	579	9	for	for	IN
cord-010027-r0tl01kq	579	10	parallel	parallel	JJ
cord-010027-r0tl01kq	579	11	testing	testing	NN
cord-010027-r0tl01kq	579	12	of	of	IN
cord-010027-r0tl01kq	579	13	ALK	ALK	NNP
cord-010027-r0tl01kq	579	14	with	with	IN
cord-010027-r0tl01kq	579	15	IHC	IHC	NNP
cord-010027-r0tl01kq	579	16	and	and	CC
cord-010027-r0tl01kq	579	17	FISH	fish	NN
cord-010027-r0tl01kq	579	18	.	.	.
cord-010027-r0tl01kq	580	1	We	-PRON-	PRP
cord-010027-r0tl01kq	580	2	observed	observe	VBD
cord-010027-r0tl01kq	580	3	100	100	CD
cord-010027-r0tl01kq	580	4	%	%	NN
cord-010027-r0tl01kq	580	5	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	580	6	(	(	-LRB-
cord-010027-r0tl01kq	580	7	7	7	CD
cord-010027-r0tl01kq	580	8	IHC+/7	IHC+/7	NNP
cord-010027-r0tl01kq	580	9	FISH+	FISH+	NNP
cord-010027-r0tl01kq	580	10	)	)	-RRB-
cord-010027-r0tl01kq	580	11	and	and	CC
cord-010027-r0tl01kq	580	12	96.6	96.6	CD
cord-010027-r0tl01kq	580	13	%	%	NN
cord-010027-r0tl01kq	580	14	specificity	specificity	NN
cord-010027-r0tl01kq	580	15	(	(	-LRB-
cord-010027-r0tl01kq	580	16	113	113	CD
cord-010027-r0tl01kq	580	17	IHC-/117	ihc-/117	CD
cord-010027-r0tl01kq	580	18	FISH-	FISH-	NNS
cord-010027-r0tl01kq	580	19	)	)	-RRB-
cord-010027-r0tl01kq	580	20	when	when	WRB
cord-010027-r0tl01kq	580	21	comparing	compare	VBG
cord-010027-r0tl01kq	580	22	IHC	IHC	NNP
cord-010027-r0tl01kq	580	23	with	with	IN
cord-010027-r0tl01kq	580	24	FISH	fish	NN
cord-010027-r0tl01kq	580	25	.	.	.
cord-010027-r0tl01kq	581	1	In	in	IN
cord-010027-r0tl01kq	581	2	conclusion	conclusion	NN
cord-010027-r0tl01kq	581	3	,	,	,
cord-010027-r0tl01kq	581	4	the	the	DT
cord-010027-r0tl01kq	581	5	prevalence	prevalence	NN
cord-010027-r0tl01kq	581	6	of	of	IN
cord-010027-r0tl01kq	581	7	EGFR	EGFR	NNP
cord-010027-r0tl01kq	581	8	mutation	mutation	NN
cord-010027-r0tl01kq	581	9	in	in	IN
cord-010027-r0tl01kq	581	10	South	South	NNP
cord-010027-r0tl01kq	581	11	East	East	NNP
cord-010027-r0tl01kq	581	12	of	of	IN
cord-010027-r0tl01kq	581	13	Scotland	Scotland	NNP
cord-010027-r0tl01kq	581	14	has	have	VBZ
cord-010027-r0tl01kq	581	15	reflected	reflect	VBN
cord-010027-r0tl01kq	581	16	mutation	mutation	NN
cord-010027-r0tl01kq	581	17	rates	rate	NNS
cord-010027-r0tl01kq	581	18	reported	report	VBN
cord-010027-r0tl01kq	581	19	in	in	IN
cord-010027-r0tl01kq	581	20	West	West	NNP
cord-010027-r0tl01kq	581	21	of	of	IN
cord-010027-r0tl01kq	581	22	Scotland	Scotland	NNP
cord-010027-r0tl01kq	581	23	.	.	.
cord-010027-r0tl01kq	582	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	582	2	findings	finding	NNS
cord-010027-r0tl01kq	582	3	further	far	RBR
cord-010027-r0tl01kq	582	4	support	support	VBP
cord-010027-r0tl01kq	582	5	the	the	DT
cord-010027-r0tl01kq	582	6	use	use	NN
cord-010027-r0tl01kq	582	7	of	of	IN
cord-010027-r0tl01kq	582	8	ALK	ALK	NNP
cord-010027-r0tl01kq	582	9	-	-	HYPH
cord-010027-r0tl01kq	582	10	IHC	IHC	NNP
cord-010027-r0tl01kq	582	11	as	as	IN
cord-010027-r0tl01kq	582	12	a	a	DT
cord-010027-r0tl01kq	582	13	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	582	14	screening	screening	NN
cord-010027-r0tl01kq	582	15	tool	tool	NN
cord-010027-r0tl01kq	582	16	.	.	.
cord-010027-r0tl01kq	583	1	Purpose	purpose	NN
cord-010027-r0tl01kq	583	2	of	of	IN
cord-010027-r0tl01kq	583	3	the	the	DT
cord-010027-r0tl01kq	583	4	Study	Study	NNP
cord-010027-r0tl01kq	583	5	:	:	:
cord-010027-r0tl01kq	583	6	The	the	DT
cord-010027-r0tl01kq	583	7	molecular	molecular	JJ
cord-010027-r0tl01kq	583	8	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	583	9	of	of	IN
cord-010027-r0tl01kq	583	10	metastasis	metastasis	NN
cord-010027-r0tl01kq	583	11	and	and	CC
cord-010027-r0tl01kq	583	12	progression	progression	NN
cord-010027-r0tl01kq	583	13	of	of	IN
cord-010027-r0tl01kq	583	14	penile	penile	JJ
cord-010027-r0tl01kq	583	15	squamous	squamous	JJ
cord-010027-r0tl01kq	583	16	cell	cell	NN
cord-010027-r0tl01kq	583	17	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	583	18	(	(	-LRB-
cord-010027-r0tl01kq	583	19	PSCC	PSCC	NNP
cord-010027-r0tl01kq	583	20	)	)	-RRB-
cord-010027-r0tl01kq	583	21	are	be	VBP
cord-010027-r0tl01kq	583	22	unclear	unclear	JJ
cord-010027-r0tl01kq	583	23	.	.	.
cord-010027-r0tl01kq	584	1	Nobody	nobody	NN
cord-010027-r0tl01kq	584	2	,	,	,
cord-010027-r0tl01kq	584	3	to	to	IN
cord-010027-r0tl01kq	584	4	our	-PRON-	PRP$
cord-010027-r0tl01kq	584	5	knowledge	knowledge	NN
cord-010027-r0tl01kq	584	6	,	,	,
cord-010027-r0tl01kq	584	7	has	have	VBZ
cord-010027-r0tl01kq	584	8	investigated	investigate	VBN
cord-010027-r0tl01kq	584	9	the	the	DT
cord-010027-r0tl01kq	584	10	expression	expression	NN
cord-010027-r0tl01kq	584	11	of	of	IN
cord-010027-r0tl01kq	584	12	cell	cell	NN
cord-010027-r0tl01kq	584	13	-	-	HYPH
cord-010027-r0tl01kq	584	14	cycle	cycle	NN
cord-010027-r0tl01kq	584	15	proteins	protein	NNS
cord-010027-r0tl01kq	584	16	in	in	IN
cord-010027-r0tl01kq	584	17	advanced	advanced	JJ
cord-010027-r0tl01kq	584	18	or	or	CC
cord-010027-r0tl01kq	584	19	metastatic	metastatic	JJ
cord-010027-r0tl01kq	584	20	PSCC	PSCC	NNP
cord-010027-r0tl01kq	584	21	.	.	.
cord-010027-r0tl01kq	585	1	We	-PRON-	PRP
cord-010027-r0tl01kq	585	2	aimed	aim	VBD
cord-010027-r0tl01kq	585	3	to	to	TO
cord-010027-r0tl01kq	585	4	determine	determine	VB
cord-010027-r0tl01kq	585	5	the	the	DT
cord-010027-r0tl01kq	585	6	extent	extent	NN
cord-010027-r0tl01kq	585	7	of	of	IN
cord-010027-r0tl01kq	585	8	HPV	hpv	NN
cord-010027-r0tl01kq	585	9	infection	infection	NN
cord-010027-r0tl01kq	585	10	in	in	IN
cord-010027-r0tl01kq	585	11	patients	patient	NNS
cord-010027-r0tl01kq	585	12	with	with	IN
cord-010027-r0tl01kq	585	13	advanced	advanced	JJ
cord-010027-r0tl01kq	585	14	PSCC	PSCC	NNP
cord-010027-r0tl01kq	585	15	and	and	CC
cord-010027-r0tl01kq	585	16	its	-PRON-	PRP$
cord-010027-r0tl01kq	585	17	effect	effect	NN
cord-010027-r0tl01kq	585	18	on	on	IN
cord-010027-r0tl01kq	585	19	the	the	DT
cord-010027-r0tl01kq	585	20	expression	expression	NN
cord-010027-r0tl01kq	585	21	of	of	IN
cord-010027-r0tl01kq	585	22	the	the	DT
cord-010027-r0tl01kq	585	23	key	key	JJ
cord-010027-r0tl01kq	585	24	cell	cell	NN
cord-010027-r0tl01kq	585	25	-	-	HYPH
cord-010027-r0tl01kq	585	26	cycle	cycle	NN
cord-010027-r0tl01kq	585	27	proteins	protein	NNS
cord-010027-r0tl01kq	585	28	p53	p53	NN
cord-010027-r0tl01kq	585	29	,	,	,
cord-010027-r0tl01kq	585	30	p16INK4A	p16ink4a	NN
cord-010027-r0tl01kq	585	31	and	and	CC
cord-010027-r0tl01kq	585	32	retinoblastoma	retinoblastoma	NN
cord-010027-r0tl01kq	585	33	(	(	-LRB-
cord-010027-r0tl01kq	585	34	RB	RB	NNP
cord-010027-r0tl01kq	585	35	)	)	-RRB-
cord-010027-r0tl01kq	585	36	.	.	.
cord-010027-r0tl01kq	586	1	Methods	method	NNS
cord-010027-r0tl01kq	586	2	:	:	:
cord-010027-r0tl01kq	587	1	Archival	archival	JJ
cord-010027-r0tl01kq	587	2	paraffin	paraffin	NN
cord-010027-r0tl01kq	587	3	embedded	embed	VBN
cord-010027-r0tl01kq	587	4	blocks	block	NNS
cord-010027-r0tl01kq	587	5	were	be	VBD
cord-010027-r0tl01kq	587	6	obtained	obtain	VBN
cord-010027-r0tl01kq	587	7	from	from	IN
cord-010027-r0tl01kq	587	8	27	27	CD
cord-010027-r0tl01kq	587	9	primary	primary	JJ
cord-010027-r0tl01kq	587	10	penile	penile	JJ
cord-010027-r0tl01kq	587	11	cancers	cancer	NNS
cord-010027-r0tl01kq	587	12	,	,	,
cord-010027-r0tl01kq	587	13	all	all	DT
cord-010027-r0tl01kq	587	14	patients	patient	NNS
cord-010027-r0tl01kq	587	15	having	have	VBG
cord-010027-r0tl01kq	587	16	developed	develop	VBN
cord-010027-r0tl01kq	587	17	locally	locally	RB
cord-010027-r0tl01kq	587	18	-	-	HYPH
cord-010027-r0tl01kq	587	19	advanced	advance	VBN
cord-010027-r0tl01kq	587	20	or	or	CC
cord-010027-r0tl01kq	587	21	metastatic	metastatic	JJ
cord-010027-r0tl01kq	587	22	disease	disease	NN
cord-010027-r0tl01kq	587	23	.	.	.
cord-010027-r0tl01kq	588	1	All	all	DT
cord-010027-r0tl01kq	588	2	patients	patient	NNS
cord-010027-r0tl01kq	588	3	were	be	VBD
cord-010027-r0tl01kq	588	4	treated	treat	VBN
cord-010027-r0tl01kq	588	5	in	in	IN
cord-010027-r0tl01kq	588	6	the	the	DT
cord-010027-r0tl01kq	588	7	Phase	Phase	NNP
cord-010027-r0tl01kq	588	8	II	II	NNP
cord-010027-r0tl01kq	588	9	Trial	Trial	NNP
cord-010027-r0tl01kq	588	10	of	of	IN
cord-010027-r0tl01kq	588	11	docetaxel	docetaxel	NNP
cord-010027-r0tl01kq	588	12	,	,	,
cord-010027-r0tl01kq	588	13	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	588	14	&	&	CC
cord-010027-r0tl01kq	588	15	5-fluorouracil	5-fluorouracil	CD
cord-010027-r0tl01kq	588	16	(	(	-LRB-
cord-010027-r0tl01kq	588	17	TPF	TPF	NNP
cord-010027-r0tl01kq	588	18	)	)	-RRB-
cord-010027-r0tl01kq	589	1	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	589	2	CRUK/09/001	CRUK/09/001	NNP
cord-010027-r0tl01kq	590	1	(	(	-LRB-
cord-010027-r0tl01kq	590	2	Nicholson	Nicholson	NNP
cord-010027-r0tl01kq	590	3	et	et	NNP
cord-010027-r0tl01kq	590	4	al	al	NNP
cord-010027-r0tl01kq	590	5	.	.	.
cord-010027-r0tl01kq	591	1	BJC	BJC	NNP
cord-010027-r0tl01kq	591	2	2013	2013	CD
cord-010027-r0tl01kq	591	3	;	;	:
cord-010027-r0tl01kq	591	4	109	109	CD
cord-010027-r0tl01kq	591	5	:	:	SYM
cord-010027-r0tl01kq	591	6	2554	2554	CD
cord-010027-r0tl01kq	591	7	-	-	SYM
cord-010027-r0tl01kq	591	8	9	9	CD
cord-010027-r0tl01kq	591	9	)	)	-RRB-
cord-010027-r0tl01kq	591	10	.	.	.
cord-010027-r0tl01kq	592	1	Samples	sample	NNS
cord-010027-r0tl01kq	592	2	were	be	VBD
cord-010027-r0tl01kq	592	3	analysed	analyse	VBN
cord-010027-r0tl01kq	592	4	immunohistochemically	immunohistochemically	RB
cord-010027-r0tl01kq	592	5	for	for	IN
cord-010027-r0tl01kq	592	6	p16INK4A	p16INK4A	NNP
cord-010027-r0tl01kq	592	7	,	,	,
cord-010027-r0tl01kq	592	8	p53	p53	NN
cord-010027-r0tl01kq	592	9	and	and	CC
cord-010027-r0tl01kq	592	10	RB	rb	NN
cord-010027-r0tl01kq	592	11	protein	protein	NN
cord-010027-r0tl01kq	592	12	expression	expression	NN
cord-010027-r0tl01kq	592	13	on	on	IN
cord-010027-r0tl01kq	592	14	a	a	DT
cord-010027-r0tl01kq	592	15	tissue	tissue	NN
cord-010027-r0tl01kq	592	16	microarray	microarray	NN
cord-010027-r0tl01kq	592	17	.	.	.
cord-010027-r0tl01kq	593	1	All	all	DT
cord-010027-r0tl01kq	593	2	tumours	tumour	NNS
cord-010027-r0tl01kq	593	3	were	be	VBD
cord-010027-r0tl01kq	593	4	HPV	HPV	NNP
cord-010027-r0tl01kq	593	5	typed	type	VBN
cord-010027-r0tl01kq	593	6	using	use	VBG
cord-010027-r0tl01kq	593	7	PCR	PCR	NNP
cord-010027-r0tl01kq	593	8	.	.	.
cord-010027-r0tl01kq	594	1	Summary	summary	NN
cord-010027-r0tl01kq	594	2	of	of	IN
cord-010027-r0tl01kq	594	3	Results	result	NNS
cord-010027-r0tl01kq	594	4	:	:	:
cord-010027-r0tl01kq	595	1	HPV	HPV	NNP
cord-010027-r0tl01kq	595	2	DNA	DNA	NNP
cord-010027-r0tl01kq	595	3	was	be	VBD
cord-010027-r0tl01kq	595	4	detected	detect	VBN
cord-010027-r0tl01kq	595	5	in	in	IN
cord-010027-r0tl01kq	595	6	8/22	8/22	CD
cord-010027-r0tl01kq	595	7	(	(	-LRB-
cord-010027-r0tl01kq	595	8	36	36	CD
cord-010027-r0tl01kq	595	9	%	%	NN
cord-010027-r0tl01kq	595	10	)	)	-RRB-
cord-010027-r0tl01kq	595	11	with	with	IN
cord-010027-r0tl01kq	595	12	HPV	HPV	NNP
cord-010027-r0tl01kq	595	13	16	16	CD
cord-010027-r0tl01kq	595	14	present	present	NN
cord-010027-r0tl01kq	595	15	in	in	IN
cord-010027-r0tl01kq	595	16	7/8	7/8	CD
cord-010027-r0tl01kq	595	17	(	(	-LRB-
cord-010027-r0tl01kq	595	18	88	88	CD
cord-010027-r0tl01kq	595	19	%	%	NN
cord-010027-r0tl01kq	595	20	)	)	-RRB-
cord-010027-r0tl01kq	595	21	.	.	.
cord-010027-r0tl01kq	596	1	5	5	CD
cord-010027-r0tl01kq	596	2	cases	case	NNS
cord-010027-r0tl01kq	596	3	were	be	VBD
cord-010027-r0tl01kq	596	4	not	not	RB
cord-010027-r0tl01kq	596	5	suitable	suitable	JJ
cord-010027-r0tl01kq	596	6	for	for	IN
cord-010027-r0tl01kq	596	7	analysis	analysis	NN
cord-010027-r0tl01kq	596	8	.	.	.
cord-010027-r0tl01kq	597	1	No	no	DT
cord-010027-r0tl01kq	597	2	association	association	NN
cord-010027-r0tl01kq	597	3	was	be	VBD
cord-010027-r0tl01kq	597	4	found	find	VBN
cord-010027-r0tl01kq	597	5	between	between	IN
cord-010027-r0tl01kq	597	6	HPV	hpv	NN
cord-010027-r0tl01kq	597	7	and	and	CC
cord-010027-r0tl01kq	597	8	expression	expression	NN
cord-010027-r0tl01kq	597	9	of	of	IN
cord-010027-r0tl01kq	597	10	either	either	DT
cord-010027-r0tl01kq	597	11	p16INK4A	p16INK4A	NNP
cord-010027-r0tl01kq	597	12	(	(	-LRB-
cord-010027-r0tl01kq	597	13	p=	p=	NNP
cord-010027-r0tl01kq	597	14	0.3426	0.3426	CD
cord-010027-r0tl01kq	597	15	)	)	-RRB-
cord-010027-r0tl01kq	597	16	,	,	,
cord-010027-r0tl01kq	597	17	p53	p53	NN
cord-010027-r0tl01kq	597	18	(	(	-LRB-
cord-010027-r0tl01kq	597	19	p=	p=	NNP
cord-010027-r0tl01kq	597	20	0.1365	0.1365	CD
cord-010027-r0tl01kq	597	21	)	)	-RRB-
cord-010027-r0tl01kq	597	22	or	or	CC
cord-010027-r0tl01kq	597	23	RB	RB	NNP
cord-010027-r0tl01kq	597	24	(	(	-LRB-
cord-010027-r0tl01kq	597	25	p=	p=	NNP
cord-010027-r0tl01kq	597	26	1	1	CD
cord-010027-r0tl01kq	597	27	)	)	-RRB-
cord-010027-r0tl01kq	597	28	using	use	VBG
cord-010027-r0tl01kq	597	29	Fisher	Fisher	NNP
cord-010027-r0tl01kq	597	30	's	's	POS
cord-010027-r0tl01kq	597	31	exact	exact	JJ
cord-010027-r0tl01kq	597	32	test	test	NN
cord-010027-r0tl01kq	597	33	.	.	.
cord-010027-r0tl01kq	598	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	598	2	:	:	:
cord-010027-r0tl01kq	599	1	HPV	HPV	NNP
cord-010027-r0tl01kq	599	2	DNA	DNA	NNP
cord-010027-r0tl01kq	599	3	is	be	VBZ
cord-010027-r0tl01kq	599	4	detected	detect	VBN
cord-010027-r0tl01kq	599	5	in	in	IN
cord-010027-r0tl01kq	599	6	less	less	JJR
cord-010027-r0tl01kq	599	7	than	than	IN
cord-010027-r0tl01kq	599	8	half	half	NN
cord-010027-r0tl01kq	599	9	of	of	IN
cord-010027-r0tl01kq	599	10	progressive	progressive	JJ
cord-010027-r0tl01kq	599	11	PSCC	PSCC	NNP
cord-010027-r0tl01kq	599	12	,	,	,
cord-010027-r0tl01kq	599	13	suggesting	suggest	VBG
cord-010027-r0tl01kq	599	14	either	either	CC
cord-010027-r0tl01kq	599	15	the	the	DT
cord-010027-r0tl01kq	599	16	loss	loss	NN
cord-010027-r0tl01kq	599	17	of	of	IN
cord-010027-r0tl01kq	599	18	HPV	hpv	NN
cord-010027-r0tl01kq	599	19	in	in	IN
cord-010027-r0tl01kq	599	20	advanced	advanced	JJ
cord-010027-r0tl01kq	599	21	disease	disease	NN
cord-010027-r0tl01kq	599	22	or	or	CC
cord-010027-r0tl01kq	599	23	that	that	IN
cord-010027-r0tl01kq	599	24	non	non	JJ
cord-010027-r0tl01kq	599	25	-	-	JJ
cord-010027-r0tl01kq	599	26	HPV	hpv	JJ
cord-010027-r0tl01kq	599	27	related	related	JJ
cord-010027-r0tl01kq	599	28	cancers	cancer	NNS
cord-010027-r0tl01kq	599	29	progress	progress	VBP
cord-010027-r0tl01kq	599	30	more	more	RBR
cord-010027-r0tl01kq	599	31	commonly	commonly	RB
cord-010027-r0tl01kq	599	32	.	.	.
cord-010027-r0tl01kq	600	1	The	the	DT
cord-010027-r0tl01kq	600	2	lack	lack	NN
cord-010027-r0tl01kq	600	3	of	of	IN
cord-010027-r0tl01kq	600	4	correlation	correlation	NN
cord-010027-r0tl01kq	600	5	between	between	IN
cord-010027-r0tl01kq	600	6	HPV	HPV	NNP
cord-010027-r0tl01kq	600	7	and	and	CC
cord-010027-r0tl01kq	600	8	these	these	DT
cord-010027-r0tl01kq	600	9	cell	cell	NN
cord-010027-r0tl01kq	600	10	-	-	HYPH
cord-010027-r0tl01kq	600	11	cycle	cycle	NN
cord-010027-r0tl01kq	600	12	proteins	protein	NNS
cord-010027-r0tl01kq	600	13	suggests	suggest	VBZ
cord-010027-r0tl01kq	600	14	that	that	IN
cord-010027-r0tl01kq	600	15	they	-PRON-	PRP
cord-010027-r0tl01kq	600	16	may	may	MD
cord-010027-r0tl01kq	600	17	undergo	undergo	VB
cord-010027-r0tl01kq	600	18	somatic	somatic	JJ
cord-010027-r0tl01kq	600	19	mutation	mutation	NN
cord-010027-r0tl01kq	600	20	that	that	WDT
cord-010027-r0tl01kq	600	21	is	be	VBZ
cord-010027-r0tl01kq	600	22	not	not	RB
cord-010027-r0tl01kq	600	23	driven	drive	VBN
cord-010027-r0tl01kq	600	24	by	by	IN
cord-010027-r0tl01kq	600	25	HPV	HPV	NNP
cord-010027-r0tl01kq	600	26	,	,	,
cord-010027-r0tl01kq	600	27	leading	lead	VBG
cord-010027-r0tl01kq	600	28	to	to	IN
cord-010027-r0tl01kq	600	29	increased	increase	VBN
cord-010027-r0tl01kq	600	30	growth	growth	NN
cord-010027-r0tl01kq	600	31	and	and	CC
cord-010027-r0tl01kq	600	32	invasiveness	invasiveness	NN
cord-010027-r0tl01kq	600	33	.	.	.
cord-010027-r0tl01kq	601	1	Treatment	treatment	NN
cord-010027-r0tl01kq	601	2	strategies	strategy	NNS
cord-010027-r0tl01kq	601	3	may	may	MD
cord-010027-r0tl01kq	601	4	be	be	VB
cord-010027-r0tl01kq	601	5	hampered	hamper	VBN
cord-010027-r0tl01kq	601	6	by	by	IN
cord-010027-r0tl01kq	601	7	this	this	DT
cord-010027-r0tl01kq	601	8	genetic	genetic	JJ
cord-010027-r0tl01kq	601	9	diversity	diversity	NN
cord-010027-r0tl01kq	601	10	,	,	,
cord-010027-r0tl01kq	601	11	which	which	WDT
cord-010027-r0tl01kq	601	12	requires	require	VBZ
cord-010027-r0tl01kq	601	13	further	further	JJ
cord-010027-r0tl01kq	601	14	investigation	investigation	NN
cord-010027-r0tl01kq	601	15	.	.	.
cord-010027-r0tl01kq	602	1	Prostate	prostate	NN
cord-010027-r0tl01kq	602	2	cancer	cancer	NN
cord-010027-r0tl01kq	602	3	is	be	VBZ
cord-010027-r0tl01kq	602	4	the	the	DT
cord-010027-r0tl01kq	602	5	second	second	JJ
cord-010027-r0tl01kq	602	6	most	most	RBS
cord-010027-r0tl01kq	602	7	common	common	JJ
cord-010027-r0tl01kq	602	8	form	form	NN
cord-010027-r0tl01kq	602	9	of	of	IN
cord-010027-r0tl01kq	602	10	cancer	cancer	NN
cord-010027-r0tl01kq	602	11	in	in	IN
cord-010027-r0tl01kq	602	12	males	male	NNS
cord-010027-r0tl01kq	602	13	,	,	,
cord-010027-r0tl01kq	602	14	and	and	CC
cord-010027-r0tl01kq	602	15	the	the	DT
cord-010027-r0tl01kq	602	16	incidence	incidence	NN
cord-010027-r0tl01kq	602	17	of	of	IN
cord-010027-r0tl01kq	602	18	this	this	DT
cord-010027-r0tl01kq	602	19	disease	disease	NN
cord-010027-r0tl01kq	602	20	is	be	VBZ
cord-010027-r0tl01kq	602	21	predicted	predict	VBN
cord-010027-r0tl01kq	602	22	to	to	TO
cord-010027-r0tl01kq	602	23	double	double	VB
cord-010027-r0tl01kq	602	24	globally	globally	RB
cord-010027-r0tl01kq	602	25	by	by	IN
cord-010027-r0tl01kq	602	26	2030	2030	CD
cord-010027-r0tl01kq	602	27	.	.	.
cord-010027-r0tl01kq	603	1	More	More	JJR
cord-010027-r0tl01kq	603	2	than	than	IN
cord-010027-r0tl01kq	603	3	1.1	1.1	CD
cord-010027-r0tl01kq	603	4	million	million	CD
cord-010027-r0tl01kq	603	5	new	new	JJ
cord-010027-r0tl01kq	603	6	cases	case	NNS
cord-010027-r0tl01kq	603	7	of	of	IN
cord-010027-r0tl01kq	603	8	prostate	prostate	NN
cord-010027-r0tl01kq	603	9	cancer	cancer	NN
cord-010027-r0tl01kq	603	10	are	be	VBP
cord-010027-r0tl01kq	603	11	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	603	12	each	each	DT
cord-010027-r0tl01kq	603	13	year	year	NN
cord-010027-r0tl01kq	603	14	and	and	CC
cord-010027-r0tl01kq	604	1	two	two	CD
cord-010027-r0tl01kq	604	2	thirds	third	NNS
cord-010027-r0tl01kq	604	3	of	of	IN
cord-010027-r0tl01kq	604	4	these	these	DT
cord-010027-r0tl01kq	604	5	patients	patient	NNS
cord-010027-r0tl01kq	604	6	are	be	VBP
cord-010027-r0tl01kq	604	7	from	from	IN
cord-010027-r0tl01kq	604	8	the	the	DT
cord-010027-r0tl01kq	604	9	Western	western	JJ
cord-010027-r0tl01kq	604	10	world	world	NN
cord-010027-r0tl01kq	604	11	.	.	.
cord-010027-r0tl01kq	605	1	Current	current	JJ
cord-010027-r0tl01kq	605	2	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	605	3	tests	test	NNS
cord-010027-r0tl01kq	605	4	for	for	IN
cord-010027-r0tl01kq	605	5	prostate	prostate	NN
cord-010027-r0tl01kq	605	6	cancer	cancer	NN
cord-010027-r0tl01kq	605	7	are	be	VBP
cord-010027-r0tl01kq	605	8	limited	limit	VBN
cord-010027-r0tl01kq	605	9	in	in	IN
cord-010027-r0tl01kq	605	10	both	both	DT
cord-010027-r0tl01kq	605	11	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	605	12	and	and	CC
cord-010027-r0tl01kq	605	13	accuracy	accuracy	NN
cord-010027-r0tl01kq	605	14	,	,	,
cord-010027-r0tl01kq	605	15	and	and	CC
cord-010027-r0tl01kq	605	16	a	a	DT
cord-010027-r0tl01kq	605	17	method	method	NN
cord-010027-r0tl01kq	605	18	for	for	IN
cord-010027-r0tl01kq	605	19	accurate	accurate	JJ
cord-010027-r0tl01kq	605	20	prognosis	prognosis	NN
cord-010027-r0tl01kq	605	21	in	in	IN
cord-010027-r0tl01kq	605	22	these	these	DT
cord-010027-r0tl01kq	605	23	patients	patient	NNS
cord-010027-r0tl01kq	605	24	is	be	VBZ
cord-010027-r0tl01kq	605	25	yet	yet	RB
cord-010027-r0tl01kq	605	26	to	to	TO
cord-010027-r0tl01kq	605	27	be	be	VB
cord-010027-r0tl01kq	605	28	developed	develop	VBN
cord-010027-r0tl01kq	605	29	;	;	:
cord-010027-r0tl01kq	605	30	therefore	therefore	RB
cord-010027-r0tl01kq	605	31	,	,	,
cord-010027-r0tl01kq	605	32	there	there	EX
cord-010027-r0tl01kq	605	33	is	be	VBZ
cord-010027-r0tl01kq	605	34	a	a	DT
cord-010027-r0tl01kq	605	35	need	need	NN
cord-010027-r0tl01kq	605	36	for	for	IN
cord-010027-r0tl01kq	605	37	a	a	DT
cord-010027-r0tl01kq	605	38	sensitive	sensitive	JJ
cord-010027-r0tl01kq	605	39	and	and	CC
cord-010027-r0tl01kq	605	40	specific	specific	JJ
cord-010027-r0tl01kq	605	41	prostate	prostate	NN
cord-010027-r0tl01kq	605	42	cancer	cancer	NN
cord-010027-r0tl01kq	605	43	test	test	NN
cord-010027-r0tl01kq	605	44	to	to	TO
cord-010027-r0tl01kq	605	45	implement	implement	VB
cord-010027-r0tl01kq	605	46	early	early	JJ
cord-010027-r0tl01kq	605	47	and	and	CC
cord-010027-r0tl01kq	605	48	appropriate	appropriate	JJ
cord-010027-r0tl01kq	605	49	therapy	therapy	NN
cord-010027-r0tl01kq	605	50	.	.	.
cord-010027-r0tl01kq	606	1	The	the	DT
cord-010027-r0tl01kq	606	2	recent	recent	JJ
cord-010027-r0tl01kq	606	3	discovery	discovery	NN
cord-010027-r0tl01kq	606	4	of	of	IN
cord-010027-r0tl01kq	606	5	altered	alter	VBN
cord-010027-r0tl01kq	606	6	endosomal	endosomal	NNP
cord-010027-r0tl01kq	606	7	-	-	HYPH
cord-010027-r0tl01kq	606	8	lysosomal	lysosomal	VBG
cord-010027-r0tl01kq	606	9	biogenesis	biogenesis	NN
cord-010027-r0tl01kq	606	10	in	in	IN
cord-010027-r0tl01kq	606	11	prostate	prostate	NN
cord-010027-r0tl01kq	606	12	cancer	cancer	NN
cord-010027-r0tl01kq	606	13	cells	cell	NNS
cord-010027-r0tl01kq	606	14	has	have	VBZ
cord-010027-r0tl01kq	606	15	identified	identify	VBN
cord-010027-r0tl01kq	606	16	a	a	DT
cord-010027-r0tl01kq	606	17	fundamental	fundamental	JJ
cord-010027-r0tl01kq	606	18	change	change	NN
cord-010027-r0tl01kq	606	19	in	in	IN
cord-010027-r0tl01kq	606	20	the	the	DT
cord-010027-r0tl01kq	606	21	cell	cell	NN
cord-010027-r0tl01kq	606	22	biology	biology	NN
cord-010027-r0tl01kq	606	23	of	of	IN
cord-010027-r0tl01kq	606	24	this	this	DT
cord-010027-r0tl01kq	606	25	cancer	cancer	NN
cord-010027-r0tl01kq	606	26	that	that	WDT
cord-010027-r0tl01kq	606	27	holds	hold	VBZ
cord-010027-r0tl01kq	606	28	great	great	JJ
cord-010027-r0tl01kq	606	29	promise	promise	NN
cord-010027-r0tl01kq	606	30	for	for	IN
cord-010027-r0tl01kq	606	31	the	the	DT
cord-010027-r0tl01kq	606	32	identification	identification	NN
cord-010027-r0tl01kq	606	33	of	of	IN
cord-010027-r0tl01kq	606	34	novel	novel	JJ
cord-010027-r0tl01kq	606	35	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	606	36	that	that	WDT
cord-010027-r0tl01kq	606	37	can	can	MD
cord-010027-r0tl01kq	606	38	predict	predict	VB
cord-010027-r0tl01kq	606	39	disease	disease	NN
cord-010027-r0tl01kq	606	40	outcomes	outcome	NNS
cord-010027-r0tl01kq	606	41	.	.	.
cord-010027-r0tl01kq	607	1	Investigation	investigation	NN
cord-010027-r0tl01kq	607	2	of	of	IN
cord-010027-r0tl01kq	607	3	the	the	DT
cord-010027-r0tl01kq	607	4	endosome	endosome	NNP
cord-010027-r0tl01kq	607	5	compartment	compartment	NN
cord-010027-r0tl01kq	607	6	and	and	CC
cord-010027-r0tl01kq	607	7	endosome	endosome	NN
cord-010027-r0tl01kq	607	8	biogenesis	biogenesis	NN
cord-010027-r0tl01kq	607	9	revealed	reveal	VBD
cord-010027-r0tl01kq	607	10	elevated	elevated	JJ
cord-010027-r0tl01kq	607	11	gene	gene	NN
cord-010027-r0tl01kq	607	12	and	and	CC
cord-010027-r0tl01kq	607	13	expression	expression	NN
cord-010027-r0tl01kq	607	14	of	of	IN
cord-010027-r0tl01kq	607	15	critical	critical	JJ
cord-010027-r0tl01kq	607	16	machinery	machinery	NN
cord-010027-r0tl01kq	607	17	components	component	NNS
cord-010027-r0tl01kq	607	18	that	that	WDT
cord-010027-r0tl01kq	607	19	are	be	VBP
cord-010027-r0tl01kq	607	20	required	require	VBN
cord-010027-r0tl01kq	607	21	for	for	IN
cord-010027-r0tl01kq	607	22	endosome	endosome	NN
cord-010027-r0tl01kq	607	23	biogenesis	biogenesis	NN
cord-010027-r0tl01kq	607	24	and	and	CC
cord-010027-r0tl01kq	607	25	endocytosis	endocytosis	NN
cord-010027-r0tl01kq	607	26	.	.	.
cord-010027-r0tl01kq	608	1	Here	here	RB
cord-010027-r0tl01kq	608	2	we	-PRON-	PRP
cord-010027-r0tl01kq	608	3	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	608	4	significantly	significantly	RB
cord-010027-r0tl01kq	608	5	altered	alter	VBN
cord-010027-r0tl01kq	608	6	expression	expression	NN
cord-010027-r0tl01kq	608	7	of	of	IN
cord-010027-r0tl01kq	608	8	endosomal	endosomal	NNP
cord-010027-r0tl01kq	608	9	and	and	CC
cord-010027-r0tl01kq	608	10	lysosomal	lysosomal	JJ
cord-010027-r0tl01kq	608	11	genes	gene	NNS
cord-010027-r0tl01kq	608	12	in	in	IN
cord-010027-r0tl01kq	608	13	mRNA	mRNA	NNP
cord-010027-r0tl01kq	608	14	microarrays	microarray	NNS
cord-010027-r0tl01kq	608	15	of	of	IN
cord-010027-r0tl01kq	608	16	prostate	prostate	NN
cord-010027-r0tl01kq	608	17	cancer	cancer	NN
cord-010027-r0tl01kq	608	18	tissue	tissue	NN
cord-010027-r0tl01kq	608	19	compared	compare	VBN
cord-010027-r0tl01kq	608	20	to	to	IN
cord-010027-r0tl01kq	608	21	non	non	JJ
cord-010027-r0tl01kq	608	22	-	-	JJ
cord-010027-r0tl01kq	608	23	malignant	malignant	JJ
cord-010027-r0tl01kq	608	24	tissue	tissue	NN
cord-010027-r0tl01kq	608	25	,	,	,
cord-010027-r0tl01kq	608	26	and	and	CC
cord-010027-r0tl01kq	608	27	that	that	DT
cord-010027-r0tl01kq	608	28	specific	specific	JJ
cord-010027-r0tl01kq	608	29	endosomal	endosomal	NNP
cord-010027-r0tl01kq	608	30	and	and	CC
cord-010027-r0tl01kq	608	31	lysosomal	lysosomal	JJ
cord-010027-r0tl01kq	608	32	genes	gene	NNS
cord-010027-r0tl01kq	608	33	are	be	VBP
cord-010027-r0tl01kq	608	34	predictive	predictive	JJ
cord-010027-r0tl01kq	608	35	of	of	IN
cord-010027-r0tl01kq	608	36	patient	patient	JJ
cord-010027-r0tl01kq	608	37	outcomes	outcome	NNS
cord-010027-r0tl01kq	608	38	.	.	.
cord-010027-r0tl01kq	609	1	Two	two	CD
cord-010027-r0tl01kq	609	2	endosomal	endosomal	JJ
cord-010027-r0tl01kq	609	3	tri	tri	JJ
cord-010027-r0tl01kq	609	4	-	-	JJ
cord-010027-r0tl01kq	609	5	gene	gene	NN
cord-010027-r0tl01kq	609	6	signatures	signature	NNS
cord-010027-r0tl01kq	609	7	were	be	VBD
cord-010027-r0tl01kq	609	8	identified	identify	VBN
cord-010027-r0tl01kq	609	9	that	that	WDT
cord-010027-r0tl01kq	609	10	had	have	VBD
cord-010027-r0tl01kq	609	11	a	a	DT
cord-010027-r0tl01kq	609	12	significant	significant	JJ
cord-010027-r0tl01kq	609	13	capacity	capacity	NN
cord-010027-r0tl01kq	609	14	to	to	TO
cord-010027-r0tl01kq	609	15	stratify	stratify	VB
cord-010027-r0tl01kq	609	16	patient	patient	JJ
cord-010027-r0tl01kq	609	17	outcomes	outcome	NNS
cord-010027-r0tl01kq	609	18	.	.	.
cord-010027-r0tl01kq	610	1	Changes	change	NNS
cord-010027-r0tl01kq	610	2	in	in	IN
cord-010027-r0tl01kq	610	3	the	the	DT
cord-010027-r0tl01kq	610	4	expression	expression	NN
cord-010027-r0tl01kq	610	5	of	of	IN
cord-010027-r0tl01kq	610	6	these	these	DT
cord-010027-r0tl01kq	610	7	genes	gene	NNS
cord-010027-r0tl01kq	610	8	was	be	VBD
cord-010027-r0tl01kq	610	9	further	further	RB
cord-010027-r0tl01kq	610	10	ascertained	ascertain	VBN
cord-010027-r0tl01kq	610	11	by	by	IN
cord-010027-r0tl01kq	610	12	qPCR	qPCR	NNP
cord-010027-r0tl01kq	610	13	in	in	IN
cord-010027-r0tl01kq	610	14	fresh	fresh	JJ
cord-010027-r0tl01kq	610	15	-	-	HYPH
cord-010027-r0tl01kq	610	16	frozen	frozen	JJ
cord-010027-r0tl01kq	610	17	prostate	prostate	NN
cord-010027-r0tl01kq	610	18	tissue	tissue	NN
cord-010027-r0tl01kq	610	19	specimens	specimen	NNS
cord-010027-r0tl01kq	610	20	,	,	,
cord-010027-r0tl01kq	610	21	which	which	WDT
cord-010027-r0tl01kq	610	22	further	further	RB
cord-010027-r0tl01kq	610	23	implicated	implicate	VBD
cord-010027-r0tl01kq	610	24	altered	altered	JJ
cord-010027-r0tl01kq	610	25	endosome	endosome	NN
cord-010027-r0tl01kq	610	26	biology	biology	NN
cord-010027-r0tl01kq	610	27	during	during	IN
cord-010027-r0tl01kq	610	28	disease	disease	NN
cord-010027-r0tl01kq	610	29	progression	progression	NN
cord-010027-r0tl01kq	610	30	,	,	,
cord-010027-r0tl01kq	610	31	with	with	IN
cord-010027-r0tl01kq	610	32	significant	significant	JJ
cord-010027-r0tl01kq	610	33	changes	change	NNS
cord-010027-r0tl01kq	610	34	in	in	IN
cord-010027-r0tl01kq	610	35	expression	expression	NN
cord-010027-r0tl01kq	610	36	observed	observe	VBN
cord-010027-r0tl01kq	610	37	between	between	IN
cord-010027-r0tl01kq	610	38	aggressive	aggressive	JJ
cord-010027-r0tl01kq	610	39	prostate	prostate	NN
cord-010027-r0tl01kq	610	40	cancer	cancer	NN
cord-010027-r0tl01kq	610	41	and	and	CC
cord-010027-r0tl01kq	610	42	indolent	indolent	JJ
cord-010027-r0tl01kq	610	43	disease	disease	NN
cord-010027-r0tl01kq	610	44	or	or	CC
cord-010027-r0tl01kq	610	45	normal	normal	JJ
cord-010027-r0tl01kq	610	46	prostate	prostate	NN
cord-010027-r0tl01kq	610	47	tissue	tissue	NN
cord-010027-r0tl01kq	610	48	.	.	.
cord-010027-r0tl01kq	611	1	These	these	DT
cord-010027-r0tl01kq	611	2	findings	finding	NNS
cord-010027-r0tl01kq	611	3	support	support	VBP
cord-010027-r0tl01kq	611	4	the	the	DT
cord-010027-r0tl01kq	611	5	initiation	initiation	NN
cord-010027-r0tl01kq	611	6	of	of	IN
cord-010027-r0tl01kq	611	7	a	a	DT
cord-010027-r0tl01kq	611	8	retrospective	retrospective	JJ
cord-010027-r0tl01kq	611	9	trial	trial	NN
cord-010027-r0tl01kq	611	10	to	to	TO
cord-010027-r0tl01kq	611	11	determine	determine	VB
cord-010027-r0tl01kq	611	12	if	if	IN
cord-010027-r0tl01kq	611	13	these	these	DT
cord-010027-r0tl01kq	611	14	new	new	JJ
cord-010027-r0tl01kq	611	15	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	611	16	can	can	MD
cord-010027-r0tl01kq	611	17	accurately	accurately	RB
cord-010027-r0tl01kq	611	18	predict	predict	VB
cord-010027-r0tl01kq	611	19	clinical	clinical	JJ
cord-010027-r0tl01kq	611	20	progression	progression	NN
cord-010027-r0tl01kq	611	21	in	in	IN
cord-010027-r0tl01kq	611	22	prostate	prostate	NN
cord-010027-r0tl01kq	611	23	cancer	cancer	NN
cord-010027-r0tl01kq	611	24	patients	patient	NNS
cord-010027-r0tl01kq	611	25	.	.	.
cord-010027-r0tl01kq	612	1	M	M	NNP
cord-010027-r0tl01kq	612	2	Craze	craze	NN
cord-010027-r0tl01kq	612	3	;	;	:
cord-010027-r0tl01kq	612	4	C	C	NNP
cord-010027-r0tl01kq	612	5	Joseph	Joseph	NNP
cord-010027-r0tl01kq	612	6	;	;	:
cord-010027-r0tl01kq	612	7	C	C	NNP
cord-010027-r0tl01kq	612	8	Nolan	Nolan	NNP
cord-010027-r0tl01kq	612	9	;	;	:
cord-010027-r0tl01kq	612	10	A	a	DT
cord-010027-r0tl01kq	612	11	Green	Green	NNP
cord-010027-r0tl01kq	612	12	;	;	:
cord-010027-r0tl01kq	612	13	EA	EA	NNP
cord-010027-r0tl01kq	612	14	Rakha	Rakha	NNP
cord-010027-r0tl01kq	612	15	;	;	:
cord-010027-r0tl01kq	612	16	IO	IO	NNP
cord-010027-r0tl01kq	612	17	Ellis	Ellis	NNP
cord-010027-r0tl01kq	612	18	;	;	:
cord-010027-r0tl01kq	612	19	P	P	NNP
cord-010027-r0tl01kq	612	20	A	A	NNP
cord-010027-r0tl01kq	612	21	Mukherjee	Mukherjee	NNP
cord-010027-r0tl01kq	612	22	University	University	NNP
cord-010027-r0tl01kq	612	23	of	of	IN
cord-010027-r0tl01kq	612	24	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	612	25	,	,	,
cord-010027-r0tl01kq	612	26	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	612	27	,	,	,
cord-010027-r0tl01kq	613	1	UK	UK	NNP
cord-010027-r0tl01kq	613	2	Introduction	introduction	NN
cord-010027-r0tl01kq	613	3	:	:	:
cord-010027-r0tl01kq	614	1	Lymphovascular	lymphovascular	JJ
cord-010027-r0tl01kq	614	2	invasion	invasion	NN
cord-010027-r0tl01kq	614	3	(	(	-LRB-
cord-010027-r0tl01kq	614	4	LVI	LVI	NNP
cord-010027-r0tl01kq	614	5	)	)	-RRB-
cord-010027-r0tl01kq	614	6	is	be	VBZ
cord-010027-r0tl01kq	614	7	an	an	DT
cord-010027-r0tl01kq	614	8	important	important	JJ
cord-010027-r0tl01kq	614	9	step	step	NN
cord-010027-r0tl01kq	614	10	in	in	IN
cord-010027-r0tl01kq	614	11	the	the	DT
cord-010027-r0tl01kq	614	12	metastatic	metastatic	JJ
cord-010027-r0tl01kq	614	13	cascade	cascade	NN
cord-010027-r0tl01kq	614	14	.	.	.
cord-010027-r0tl01kq	615	1	Identification	identification	NN
cord-010027-r0tl01kq	615	2	of	of	IN
cord-010027-r0tl01kq	615	3	a	a	DT
cord-010027-r0tl01kq	615	4	molecular	molecular	JJ
cord-010027-r0tl01kq	615	5	signature	signature	NN
cord-010027-r0tl01kq	615	6	for	for	IN
cord-010027-r0tl01kq	615	7	the	the	DT
cord-010027-r0tl01kq	615	8	LVI	LVI	NNP
cord-010027-r0tl01kq	615	9	positive	positive	JJ
cord-010027-r0tl01kq	615	10	phenotype	phenotype	NN
cord-010027-r0tl01kq	615	11	will	will	MD
cord-010027-r0tl01kq	615	12	help	help	VB
cord-010027-r0tl01kq	615	13	identify	identify	VB
cord-010027-r0tl01kq	615	14	relevant	relevant	JJ
cord-010027-r0tl01kq	615	15	drivers	driver	NNS
cord-010027-r0tl01kq	615	16	and	and	CC
cord-010027-r0tl01kq	615	17	pathways	pathway	NNS
cord-010027-r0tl01kq	615	18	.	.	.
cord-010027-r0tl01kq	616	1	This	this	DT
cord-010027-r0tl01kq	616	2	study	study	NN
cord-010027-r0tl01kq	616	3	aimed	aim	VBD
cord-010027-r0tl01kq	616	4	to	to	TO
cord-010027-r0tl01kq	616	5	investigate	investigate	VB
cord-010027-r0tl01kq	616	6	determinants	determinant	NNS
cord-010027-r0tl01kq	616	7	of	of	IN
cord-010027-r0tl01kq	616	8	LVI	LVI	NNP
cord-010027-r0tl01kq	616	9	from	from	IN
cord-010027-r0tl01kq	616	10	a	a	DT
cord-010027-r0tl01kq	616	11	biomarker	biomarker	NN
cord-010027-r0tl01kq	616	12	database	database	NN
cord-010027-r0tl01kq	616	13	.	.	.
cord-010027-r0tl01kq	617	1	Methods	method	NNS
cord-010027-r0tl01kq	617	2	:	:	:
cord-010027-r0tl01kq	617	3	Biomarkers	Biomarkers	NNPS
cord-010027-r0tl01kq	617	4	(	(	-LRB-
cord-010027-r0tl01kq	617	5	n	n	NN
cord-010027-r0tl01kq	617	6	>	>	XX
cord-010027-r0tl01kq	617	7	200	200	CD
cord-010027-r0tl01kq	617	8	)	)	-RRB-
cord-010027-r0tl01kq	617	9	from	from	IN
cord-010027-r0tl01kq	617	10	a	a	DT
cord-010027-r0tl01kq	617	11	well	well	RB
cord-010027-r0tl01kq	617	12	annotated	annotate	VBN
cord-010027-r0tl01kq	617	13	series	series	NN
cord-010027-r0tl01kq	617	14	(	(	-LRB-
cord-010027-r0tl01kq	617	15	n=1929	n=1929	CD
cord-010027-r0tl01kq	617	16	)	)	-RRB-
cord-010027-r0tl01kq	617	17	were	be	VBD
cord-010027-r0tl01kq	617	18	analysed	analyse	VBN
cord-010027-r0tl01kq	617	19	for	for	IN
cord-010027-r0tl01kq	617	20	correlations	correlation	NNS
cord-010027-r0tl01kq	617	21	with	with	IN
cord-010027-r0tl01kq	617	22	LVI	LVI	NNP
cord-010027-r0tl01kq	617	23	[	[	-LRB-
cord-010027-r0tl01kq	617	24	clinical	clinical	JJ
cord-010027-r0tl01kq	617	25	/	/	SYM
cord-010027-r0tl01kq	617	26	IHC	IHC	NNP
cord-010027-r0tl01kq	617	27	(	(	-LRB-
cord-010027-r0tl01kq	617	28	D2	D2	NNP
cord-010027-r0tl01kq	617	29	-	-	HYPH
cord-010027-r0tl01kq	617	30	40	40	CD
cord-010027-r0tl01kq	617	31	)	)	-RRB-
cord-010027-r0tl01kq	617	32	supplemented	supplement	VBD
cord-010027-r0tl01kq	617	33	]	]	-RRB-
cord-010027-r0tl01kq	617	34	.	.	.
cord-010027-r0tl01kq	618	1	Proteins	protein	NNS
cord-010027-r0tl01kq	618	2	with	with	IN
cord-010027-r0tl01kq	618	3	significant	significant	JJ
cord-010027-r0tl01kq	618	4	associations	association	NNS
cord-010027-r0tl01kq	618	5	with	with	IN
cord-010027-r0tl01kq	618	6	LVI	LVI	NNP
cord-010027-r0tl01kq	618	7	were	be	VBD
cord-010027-r0tl01kq	618	8	interrogated	interrogate	VBN
cord-010027-r0tl01kq	618	9	for	for	IN
cord-010027-r0tl01kq	618	10	pathway	pathway	NN
cord-010027-r0tl01kq	618	11	enrichment	enrichment	NN
cord-010027-r0tl01kq	618	12	analysis	analysis	NN
cord-010027-r0tl01kq	618	13	[	[	-LRB-
cord-010027-r0tl01kq	618	14	corrected	correct	VBN
cord-010027-r0tl01kq	618	15	for	for	IN
cord-010027-r0tl01kq	618	16	false	false	JJ
cord-010027-r0tl01kq	618	17	discovery	discovery	NN
cord-010027-r0tl01kq	618	18	rate	rate	NN
cord-010027-r0tl01kq	618	19	(	(	-LRB-
cord-010027-r0tl01kq	618	20	FDR	FDR	NNP
cord-010027-r0tl01kq	618	21	)	)	-RRB-
cord-010027-r0tl01kq	618	22	]	]	-RRB-
cord-010027-r0tl01kq	618	23	,	,	,
cord-010027-r0tl01kq	618	24	using	use	VBG
cord-010027-r0tl01kq	618	25	the	the	DT
cord-010027-r0tl01kq	618	26	STRING	string	NN
cord-010027-r0tl01kq	618	27	9.1	9.1	CD
cord-010027-r0tl01kq	618	28	platform	platform	NN
cord-010027-r0tl01kq	618	29	incorporating	incorporate	VBG
cord-010027-r0tl01kq	618	30	Gene	Gene	NNP
cord-010027-r0tl01kq	618	31	Ontology	Ontology	NNP
cord-010027-r0tl01kq	618	32	(	(	-LRB-
cord-010027-r0tl01kq	618	33	GO	GO	NNP
cord-010027-r0tl01kq	618	34	)	)	-RRB-
cord-010027-r0tl01kq	618	35	,	,	,
cord-010027-r0tl01kq	618	36	KEGG	KEGG	NNP
cord-010027-r0tl01kq	618	37	and	and	CC
cord-010027-r0tl01kq	618	38	NCI	NCI	NNP
cord-010027-r0tl01kq	618	39	.	.	.
cord-010027-r0tl01kq	619	1	Results	result	NNS
cord-010027-r0tl01kq	619	2	:	:	:
cord-010027-r0tl01kq	620	1	Biomarker	Biomarker	NNP
cord-010027-r0tl01kq	620	2	analysis	analysis	NN
cord-010027-r0tl01kq	620	3	related	relate	VBN
cord-010027-r0tl01kq	620	4	to	to	IN
cord-010027-r0tl01kq	620	5	both	both	CC
cord-010027-r0tl01kq	620	6	clinical	clinical	JJ
cord-010027-r0tl01kq	620	7	/	/	SYM
cord-010027-r0tl01kq	620	8	IHC	IHC	NNP
cord-010027-r0tl01kq	620	9	determined	determine	VBD
cord-010027-r0tl01kq	620	10	LVI	LVI	NNP
cord-010027-r0tl01kq	620	11	identified	identify	VBD
cord-010027-r0tl01kq	620	12	35	35	CD
cord-010027-r0tl01kq	620	13	positively	positively	RB
cord-010027-r0tl01kq	620	14	associated	associate	VBN
cord-010027-r0tl01kq	620	15	markers	marker	NNS
cord-010027-r0tl01kq	620	16	,	,	,
cord-010027-r0tl01kq	620	17	14	14	CD
cord-010027-r0tl01kq	620	18	in	in	IN
cord-010027-r0tl01kq	620	19	both	both	CC
cord-010027-r0tl01kq	620	20	clinical	clinical	JJ
cord-010027-r0tl01kq	620	21	and	and	CC
cord-010027-r0tl01kq	620	22	IHC	IHC	NNP
cord-010027-r0tl01kq	620	23	categories	category	NNS
cord-010027-r0tl01kq	620	24	(	(	-LRB-
cord-010027-r0tl01kq	620	25	e.g.	e.g.	RB
cord-010027-r0tl01kq	620	26	ADA3	ADA3	NNP
cord-010027-r0tl01kq	620	27	,	,	,
cord-010027-r0tl01kq	620	28	CD8	CD8	NNP
cord-010027-r0tl01kq	620	29	,	,	,
cord-010027-r0tl01kq	620	30	FOXP3	FOXP3	NNP
cord-010027-r0tl01kq	620	31	,	,	,
cord-010027-r0tl01kq	620	32	KPNA2	KPNA2	NNP
cord-010027-r0tl01kq	620	33	)	)	-RRB-
cord-010027-r0tl01kq	620	34	.	.	.
cord-010027-r0tl01kq	621	1	A	a	DT
cord-010027-r0tl01kq	621	2	further	further	JJ
cord-010027-r0tl01kq	621	3	21	21	CD
cord-010027-r0tl01kq	621	4	markers	marker	NNS
cord-010027-r0tl01kq	621	5	were	be	VBD
cord-010027-r0tl01kq	621	6	negatively	negatively	RB
cord-010027-r0tl01kq	621	7	associated	associate	VBN
cord-010027-r0tl01kq	621	8	,	,	,
cord-010027-r0tl01kq	621	9	8	8	CD
cord-010027-r0tl01kq	621	10	in	in	IN
cord-010027-r0tl01kq	621	11	both	both	DT
cord-010027-r0tl01kq	621	12	categories	category	NNS
cord-010027-r0tl01kq	621	13	(	(	-LRB-
cord-010027-r0tl01kq	621	14	e.g.	e.g.	RB
cord-010027-r0tl01kq	621	15	Bcl2	Bcl2	NNP
cord-010027-r0tl01kq	621	16	,	,	,
cord-010027-r0tl01kq	621	17	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	621	18	,	,	,
cord-010027-r0tl01kq	621	19	MAGE3	MAGE3	NNP
cord-010027-r0tl01kq	621	20	and	and	CC
cord-010027-r0tl01kq	621	21	SOX10	SOX10	NNP
cord-010027-r0tl01kq	621	22	)	)	-RRB-
cord-010027-r0tl01kq	621	23	.	.	.
cord-010027-r0tl01kq	622	1	Significant	significant	JJ
cord-010027-r0tl01kq	622	2	pathways	pathway	NNS
cord-010027-r0tl01kq	622	3	(	(	-LRB-
cord-010027-r0tl01kq	622	4	p<0.001	p<0.001	JJ
cord-010027-r0tl01kq	622	5	)	)	-RRB-
cord-010027-r0tl01kq	622	6	unifying	unify	VBG
cord-010027-r0tl01kq	622	7	the	the	DT
cord-010027-r0tl01kq	622	8	positively	positively	RB
cord-010027-r0tl01kq	622	9	associated	associate	VBN
cord-010027-r0tl01kq	622	10	proteins	protein	NNS
cord-010027-r0tl01kq	622	11	include	include	VBP
cord-010027-r0tl01kq	622	12	metabolism	metabolism	NN
cord-010027-r0tl01kq	622	13	,	,	,
cord-010027-r0tl01kq	622	14	immune	immune	JJ
cord-010027-r0tl01kq	622	15	responses	response	NNS
cord-010027-r0tl01kq	622	16	(	(	-LRB-
cord-010027-r0tl01kq	622	17	T	t	NN
cord-010027-r0tl01kq	622	18	-	-	HYPH
cord-010027-r0tl01kq	622	19	cell	cell	NN
cord-010027-r0tl01kq	622	20	regulation	regulation	NN
cord-010027-r0tl01kq	622	21	and	and	CC
cord-010027-r0tl01kq	622	22	differentiation	differentiation	NN
cord-010027-r0tl01kq	622	23	)	)	-RRB-
cord-010027-r0tl01kq	622	24	,	,	,
cord-010027-r0tl01kq	622	25	cell	cell	NN
cord-010027-r0tl01kq	622	26	activation	activation	NN
cord-010027-r0tl01kq	622	27	and	and	CC
cord-010027-r0tl01kq	622	28	transcription	transcription	NN
cord-010027-r0tl01kq	622	29	[	[	-LRB-
cord-010027-r0tl01kq	622	30	GO	go	NN
cord-010027-r0tl01kq	622	31	]	]	-RRB-
cord-010027-r0tl01kq	622	32	;	;	:
cord-010027-r0tl01kq	622	33	T	t	NN
cord-010027-r0tl01kq	622	34	-	-	HYPH
cord-010027-r0tl01kq	622	35	cell	cell	NN
cord-010027-r0tl01kq	622	36	receptor	receptor	NN
cord-010027-r0tl01kq	622	37	signalling	signal	VBG
cord-010027-r0tl01kq	622	38	pathways	pathway	NNS
cord-010027-r0tl01kq	622	39	and	and	CC
cord-010027-r0tl01kq	622	40	pathways	pathway	NNS
cord-010027-r0tl01kq	622	41	in	in	IN
cord-010027-r0tl01kq	622	42	cancer	cancer	NN
cord-010027-r0tl01kq	622	43	and	and	CC
cord-010027-r0tl01kq	622	44	haematopoietic	haematopoietic	JJ
cord-010027-r0tl01kq	622	45	cell	cell	NN
cord-010027-r0tl01kq	622	46	lineages	lineage	NNS
cord-010027-r0tl01kq	622	47	[	[	-LRB-
cord-010027-r0tl01kq	622	48	KEGG	KEGG	NNP
cord-010027-r0tl01kq	622	49	]	]	-RRB-
cord-010027-r0tl01kq	622	50	.	.	.
cord-010027-r0tl01kq	623	1	For	for	IN
cord-010027-r0tl01kq	623	2	negatively	negatively	RB
cord-010027-r0tl01kq	623	3	associated	associate	VBN
cord-010027-r0tl01kq	623	4	proteins	protein	NNS
cord-010027-r0tl01kq	623	5	,	,	,
cord-010027-r0tl01kq	623	6	the	the	DT
cord-010027-r0tl01kq	623	7	following	follow	VBG
cord-010027-r0tl01kq	623	8	were	be	VBD
cord-010027-r0tl01kq	623	9	significant	significant	JJ
cord-010027-r0tl01kq	623	10	:	:	:
cord-010027-r0tl01kq	623	11	ubiquitination	ubiquitination	NN
cord-010027-r0tl01kq	623	12	processes	process	NNS
cord-010027-r0tl01kq	623	13	,	,	,
cord-010027-r0tl01kq	623	14	regulation	regulation	NN
cord-010027-r0tl01kq	623	15	of	of	IN
cord-010027-r0tl01kq	623	16	the	the	DT
cord-010027-r0tl01kq	623	17	mitosis	mitosis	NN
cord-010027-r0tl01kq	623	18	[	[	-LRB-
cord-010027-r0tl01kq	623	19	GO	go	VB
cord-010027-r0tl01kq	623	20	]	]	-RRB-
cord-010027-r0tl01kq	623	21	;	;	:
cord-010027-r0tl01kq	623	22	p53	p53	NN
cord-010027-r0tl01kq	623	23	pathways	pathway	NNS
cord-010027-r0tl01kq	623	24	[	[	-LRB-
cord-010027-r0tl01kq	623	25	KEGG	KEGG	NNP
cord-010027-r0tl01kq	623	26	]	]	-RRB-
cord-010027-r0tl01kq	623	27	and	and	CC
cord-010027-r0tl01kq	623	28	apoptotic	apoptotic	JJ
cord-010027-r0tl01kq	623	29	and	and	CC
cord-010027-r0tl01kq	623	30	cell	cell	NN
cord-010027-r0tl01kq	623	31	cycle	cycle	NN
cord-010027-r0tl01kq	623	32	pathways	pathway	NNS
cord-010027-r0tl01kq	623	33	[	[	-LRB-
cord-010027-r0tl01kq	623	34	GO	go	VB
cord-010027-r0tl01kq	623	35	&	&	CC
cord-010027-r0tl01kq	623	36	KEGG	KEGG	NNP
cord-010027-r0tl01kq	623	37	]	]	-RRB-
cord-010027-r0tl01kq	623	38	.	.	.
cord-010027-r0tl01kq	624	1	On	on	IN
cord-010027-r0tl01kq	624	2	cross	cross	NN
cord-010027-r0tl01kq	624	3	-	-	JJ
cord-010027-r0tl01kq	624	4	validating	validate	VBG
cord-010027-r0tl01kq	624	5	a	a	DT
cord-010027-r0tl01kq	624	6	subset	subset	NN
cord-010027-r0tl01kq	624	7	included	include	VBN
cord-010027-r0tl01kq	624	8	in	in	IN
cord-010027-r0tl01kq	624	9	the	the	DT
cord-010027-r0tl01kq	624	10	METABRIC	METABRIC	NNP
cord-010027-r0tl01kq	624	11	cohort	cohort	NN
cord-010027-r0tl01kq	624	12	,	,	,
cord-010027-r0tl01kq	624	13	there	there	EX
cord-010027-r0tl01kq	624	14	were	be	VBD
cord-010027-r0tl01kq	624	15	overlapping	overlap	VBG
cord-010027-r0tl01kq	624	16	enrichments	enrichment	NNS
cord-010027-r0tl01kq	624	17	for	for	IN
cord-010027-r0tl01kq	624	18	immune	immune	JJ
cord-010027-r0tl01kq	624	19	response	response	NN
cord-010027-r0tl01kq	624	20	regulation	regulation	NN
cord-010027-r0tl01kq	624	21	(	(	-LRB-
cord-010027-r0tl01kq	624	22	GO	GO	NNP
cord-010027-r0tl01kq	624	23	)	)	-RRB-
cord-010027-r0tl01kq	624	24	and	and	CC
cord-010027-r0tl01kq	624	25	haematopoietic	haematopoietic	JJ
cord-010027-r0tl01kq	624	26	cell	cell	NN
cord-010027-r0tl01kq	624	27	lineages	lineage	NNS
cord-010027-r0tl01kq	624	28	(	(	-LRB-
cord-010027-r0tl01kq	624	29	KEGG	KEGG	NNP
cord-010027-r0tl01kq	624	30	)	)	-RRB-
cord-010027-r0tl01kq	624	31	.	.	.
cord-010027-r0tl01kq	625	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	625	2	:	:	:
cord-010027-r0tl01kq	626	1	These	these	DT
cord-010027-r0tl01kq	626	2	preliminary	preliminary	JJ
cord-010027-r0tl01kq	626	3	findings	finding	NNS
cord-010027-r0tl01kq	626	4	are	be	VBP
cord-010027-r0tl01kq	626	5	the	the	DT
cord-010027-r0tl01kq	626	6	first	first	JJ
cord-010027-r0tl01kq	626	7	to	to	TO
cord-010027-r0tl01kq	626	8	unify	unify	VB
cord-010027-r0tl01kq	626	9	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	626	10	for	for	IN
cord-010027-r0tl01kq	626	11	LVI	LVI	NNP
cord-010027-r0tl01kq	626	12	pathway	pathway	NN
cord-010027-r0tl01kq	626	13	analysis	analysis	NN
cord-010027-r0tl01kq	626	14	in	in	IN
cord-010027-r0tl01kq	626	15	BC	BC	NNP
cord-010027-r0tl01kq	626	16	,	,	,
cord-010027-r0tl01kq	626	17	using	use	VBG
cord-010027-r0tl01kq	626	18	protein	protein	NN
cord-010027-r0tl01kq	626	19	based	base	VBN
cord-010027-r0tl01kq	626	20	data	datum	NNS
cord-010027-r0tl01kq	626	21	.	.	.
cord-010027-r0tl01kq	627	1	Within	within	IN
cord-010027-r0tl01kq	627	2	the	the	DT
cord-010027-r0tl01kq	627	3	constraints	constraint	NNS
cord-010027-r0tl01kq	627	4	of	of	IN
cord-010027-r0tl01kq	627	5	selection	selection	NN
cord-010027-r0tl01kq	627	6	bias	bias	NN
cord-010027-r0tl01kq	627	7	,	,	,
cord-010027-r0tl01kq	627	8	data	datum	NNS
cord-010027-r0tl01kq	627	9	mining	mining	NN
cord-010027-r0tl01kq	627	10	from	from	IN
cord-010027-r0tl01kq	627	11	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	627	12	of	of	IN
cord-010027-r0tl01kq	627	13	multiple	multiple	JJ
cord-010027-r0tl01kq	627	14	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	627	15	in	in	IN
cord-010027-r0tl01kq	627	16	relation	relation	NN
cord-010027-r0tl01kq	627	17	to	to	IN
cord-010027-r0tl01kq	627	18	biological	biological	JJ
cord-010027-r0tl01kq	627	19	processes	process	NNS
cord-010027-r0tl01kq	627	20	hold	hold	VBP
cord-010027-r0tl01kq	627	21	promise	promise	NN
cord-010027-r0tl01kq	627	22	.	.	.
cord-010027-r0tl01kq	628	1	*	*	NFP
cord-010027-r0tl01kq	628	2	AM	am	VBP
cord-010027-r0tl01kq	628	3	supported	support	VBN
cord-010027-r0tl01kq	628	4	by	by	IN
cord-010027-r0tl01kq	628	5	the	the	DT
cord-010027-r0tl01kq	628	6	NIHR	NIHR	NNP
cord-010027-r0tl01kq	628	7	and	and	CC
cord-010027-r0tl01kq	628	8	the	the	DT
cord-010027-r0tl01kq	628	9	Academy	Academy	NNP
cord-010027-r0tl01kq	628	10	of	of	IN
cord-010027-r0tl01kq	628	11	Medical	Medical	NNP
cord-010027-r0tl01kq	628	12	Sciences	Sciences	NNPS
cord-010027-r0tl01kq	629	1	ABSTRACTS	abstract	NNS
cord-010027-r0tl01kq	630	1	S·17	S·17	NNP
cord-010027-r0tl01kq	630	2	Assessment	Assessment	NNP
cord-010027-r0tl01kq	630	3	of	of	IN
cord-010027-r0tl01kq	630	4	HER2	HER2	NNP
cord-010027-r0tl01kq	630	5	Status	Status	NNP
cord-010027-r0tl01kq	630	6	on	on	IN
cord-010027-r0tl01kq	630	7	Needle	Needle	NNP
cord-010027-r0tl01kq	630	8	Core	Core	NNP
cord-010027-r0tl01kq	630	9	Biopsy	Biopsy	NNP
cord-010027-r0tl01kq	630	10	of	of	IN
cord-010027-r0tl01kq	630	11	Breast	Breast	NNP
cord-010027-r0tl01kq	630	12	Cancer	Cancer	NNP
cord-010027-r0tl01kq	630	13	:	:	:
cord-010027-r0tl01kq	631	1	Impact	impact	NN
cord-010027-r0tl01kq	631	2	of	of	IN
cord-010027-r0tl01kq	631	3	Histopathological	Histopathological	NNP
cord-010027-r0tl01kq	631	4	Concordance	Concordance	NNP
cord-010027-r0tl01kq	631	5	P	P	NNP
cord-010027-r0tl01kq	631	6	M	M	NNP
cord-010027-r0tl01kq	631	7	Pigera	Pigera	NNP
cord-010027-r0tl01kq	631	8	;	;	:
cord-010027-r0tl01kq	632	1	AHS	AHS	NNP
cord-010027-r0tl01kq	632	2	Lee	Lee	NNP
cord-010027-r0tl01kq	632	3	;	;	:
cord-010027-r0tl01kq	632	4	IO	IO	NNP
cord-010027-r0tl01kq	632	5	Ellis	Ellis	NNP
cord-010027-r0tl01kq	632	6	;	;	:
cord-010027-r0tl01kq	632	7	EA	EA	NNP
cord-010027-r0tl01kq	632	8	Rakha	Rakha	NNP
cord-010027-r0tl01kq	632	9	;	;	:
cord-010027-r0tl01kq	632	10	Z	Z	NNP
cord-010027-r0tl01kq	632	11	Hodi	Hodi	NNP
cord-010027-r0tl01kq	632	12	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	632	13	City	City	NNP
cord-010027-r0tl01kq	632	14	Hospital	Hospital	NNP
cord-010027-r0tl01kq	632	15	,	,	,
cord-010027-r0tl01kq	632	16	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	632	17	,	,	,
cord-010027-r0tl01kq	632	18	UK	UK	NNP
cord-010027-r0tl01kq	632	19	One	one	CD
cord-010027-r0tl01kq	632	20	of	of	IN
cord-010027-r0tl01kq	632	21	the	the	DT
cord-010027-r0tl01kq	632	22	key	key	JJ
cord-010027-r0tl01kq	632	23	recommendations	recommendation	NNS
cord-010027-r0tl01kq	632	24	introduced	introduce	VBN
cord-010027-r0tl01kq	632	25	in	in	IN
cord-010027-r0tl01kq	632	26	the	the	DT
cord-010027-r0tl01kq	632	27	ASCO	ASCO	NNP
cord-010027-r0tl01kq	632	28	/	/	SYM
cord-010027-r0tl01kq	632	29	CAP	CAP	NNP
cord-010027-r0tl01kq	632	30	update	update	NN
cord-010027-r0tl01kq	632	31	guideline	guideline	NN
cord-010027-r0tl01kq	632	32	recommendation	recommendation	NN
cord-010027-r0tl01kq	632	33	on	on	IN
cord-010027-r0tl01kq	632	34	HER2	HER2	NNP
cord-010027-r0tl01kq	632	35	testing	testing	NN
cord-010027-r0tl01kq	632	36	is	be	VBZ
cord-010027-r0tl01kq	632	37	the	the	DT
cord-010027-r0tl01kq	632	38	novel	novel	JJ
cord-010027-r0tl01kq	632	39	concept	concept	NN
cord-010027-r0tl01kq	632	40	of	of	IN
cord-010027-r0tl01kq	632	41	"	"	``
cord-010027-r0tl01kq	632	42	histopathological	histopathological	NNP
cord-010027-r0tl01kq	632	43	concordance	concordance	NN
cord-010027-r0tl01kq	632	44	.	.	.
cord-010027-r0tl01kq	633	1	"	"	``
cord-010027-r0tl01kq	633	2	It	-PRON-	PRP
cord-010027-r0tl01kq	633	3	is	be	VBZ
cord-010027-r0tl01kq	633	4	proposed	propose	VBN
cord-010027-r0tl01kq	633	5	that	that	IN
cord-010027-r0tl01kq	633	6	certain	certain	JJ
cord-010027-r0tl01kq	633	7	tumour	tumour	NN
cord-010027-r0tl01kq	633	8	morphological	morphological	JJ
cord-010027-r0tl01kq	633	9	features	feature	NNS
cord-010027-r0tl01kq	633	10	such	such	JJ
cord-010027-r0tl01kq	633	11	as	as	IN
cord-010027-r0tl01kq	633	12	histologic	histologic	JJ
cord-010027-r0tl01kq	633	13	type	type	NN
cord-010027-r0tl01kq	633	14	and	and	CC
cord-010027-r0tl01kq	633	15	grade	grade	NN
cord-010027-r0tl01kq	633	16	should	should	MD
cord-010027-r0tl01kq	633	17	trigger	trigger	VB
cord-010027-r0tl01kq	633	18	repeating	repeat	VBG
cord-010027-r0tl01kq	633	19	a	a	DT
cord-010027-r0tl01kq	633	20	molecular	molecular	JJ
cord-010027-r0tl01kq	633	21	test	test	NN
cord-010027-r0tl01kq	633	22	in	in	IN
cord-010027-r0tl01kq	633	23	cases	case	NNS
cord-010027-r0tl01kq	633	24	of	of	IN
cord-010027-r0tl01kq	633	25	"	"	``
cord-010027-r0tl01kq	633	26	discordance	discordance	NN
cord-010027-r0tl01kq	633	27	"	"	''
cord-010027-r0tl01kq	633	28	.	.	.
cord-010027-r0tl01kq	634	1	In	in	IN
cord-010027-r0tl01kq	634	2	this	this	DT
cord-010027-r0tl01kq	634	3	study	study	NN
cord-010027-r0tl01kq	634	4	we	-PRON-	PRP
cord-010027-r0tl01kq	634	5	have	have	VBP
cord-010027-r0tl01kq	634	6	we	-PRON-	PRP
cord-010027-r0tl01kq	634	7	have	have	VBP
cord-010027-r0tl01kq	634	8	reviewed	review	VBN
cord-010027-r0tl01kq	634	9	3104	3104	CD
cord-010027-r0tl01kq	634	10	breast	breast	NN
cord-010027-r0tl01kq	634	11	cancer	cancer	NN
cord-010027-r0tl01kq	634	12	cases	case	NNS
cord-010027-r0tl01kq	634	13	consecutively	consecutively	RB
cord-010027-r0tl01kq	634	14	reported	report	VBN
cord-010027-r0tl01kq	634	15	in	in	IN
cord-010027-r0tl01kq	634	16	routine	routine	JJ
cord-010027-r0tl01kq	634	17	practice	practice	NN
cord-010027-r0tl01kq	634	18	in	in	IN
cord-010027-r0tl01kq	634	19	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	634	20	in	in	IN
cord-010027-r0tl01kq	634	21	the	the	DT
cord-010027-r0tl01kq	634	22	last	last	JJ
cord-010027-r0tl01kq	634	23	4	4	CD
cord-010027-r0tl01kq	634	24	years	year	NNS
cord-010027-r0tl01kq	634	25	.	.	.
cord-010027-r0tl01kq	635	1	Data	datum	NNS
cord-010027-r0tl01kq	635	2	on	on	IN
cord-010027-r0tl01kq	635	3	HER2	HER2	NNP
cord-010027-r0tl01kq	635	4	status	status	NN
cord-010027-r0tl01kq	635	5	was	be	VBD
cord-010027-r0tl01kq	635	6	collected	collect	VBN
cord-010027-r0tl01kq	635	7	and	and	CC
cord-010027-r0tl01kq	635	8	cases	case	NNS
cord-010027-r0tl01kq	635	9	with	with	IN
cord-010027-r0tl01kq	635	10	HER2	HER2	NNP
cord-010027-r0tl01kq	635	11	assessed	assess	VBN
cord-010027-r0tl01kq	635	12	on	on	IN
cord-010027-r0tl01kq	635	13	resection	resection	NN
cord-010027-r0tl01kq	635	14	specimens	specimen	NNS
cord-010027-r0tl01kq	635	15	(	(	-LRB-
cord-010027-r0tl01kq	635	16	RS	rs	NN
cord-010027-r0tl01kq	635	17	)	)	-RRB-
cord-010027-r0tl01kq	635	18	were	be	VBD
cord-010027-r0tl01kq	635	19	analysed	analyse	VBN
cord-010027-r0tl01kq	635	20	in	in	IN
cord-010027-r0tl01kq	635	21	details	detail	NNS
cord-010027-r0tl01kq	635	22	.	.	.
cord-010027-r0tl01kq	636	1	Results	result	NNS
cord-010027-r0tl01kq	636	2	:	:	:
cord-010027-r0tl01kq	636	3	of	of	IN
cord-010027-r0tl01kq	636	4	all	all	DT
cord-010027-r0tl01kq	636	5	cases	case	NNS
cord-010027-r0tl01kq	636	6	,	,	,
cord-010027-r0tl01kq	637	1	98	98	CD
cord-010027-r0tl01kq	637	2	patients	patient	NNS
cord-010027-r0tl01kq	637	3	(	(	-LRB-
cord-010027-r0tl01kq	637	4	3	3	CD
cord-010027-r0tl01kq	637	5	%	%	NN
cord-010027-r0tl01kq	637	6	)	)	-RRB-
cord-010027-r0tl01kq	637	7	had	have	VBD
cord-010027-r0tl01kq	637	8	HER2	HER2	NNP
cord-010027-r0tl01kq	637	9	status	status	NN
cord-010027-r0tl01kq	637	10	assessed	assess	VBN
cord-010027-r0tl01kq	637	11	on	on	IN
cord-010027-r0tl01kq	637	12	core	core	NN
cord-010027-r0tl01kq	637	13	biopsy	biopsy	NN
cord-010027-r0tl01kq	637	14	and	and	CC
cord-010027-r0tl01kq	637	15	the	the	DT
cord-010027-r0tl01kq	637	16	corresponding	corresponding	JJ
cord-010027-r0tl01kq	637	17	tumour	tumour	NN
cord-010027-r0tl01kq	637	18	RS	rs	NN
cord-010027-r0tl01kq	637	19	.	.	.
cord-010027-r0tl01kq	638	1	The	the	DT
cord-010027-r0tl01kq	638	2	main	main	JJ
cord-010027-r0tl01kq	638	3	reasons	reason	NNS
cord-010027-r0tl01kq	638	4	for	for	IN
cord-010027-r0tl01kq	638	5	a	a	DT
cord-010027-r0tl01kq	638	6	repeat	repeat	NN
cord-010027-r0tl01kq	638	7	were	be	VBD
cord-010027-r0tl01kq	638	8	tumour	tumour	NN
cord-010027-r0tl01kq	638	9	multifocality	multifocality	NN
cord-010027-r0tl01kq	638	10	and	and	CC
cord-010027-r0tl01kq	638	11	morphologically	morphologically	RB
cord-010027-r0tl01kq	638	12	different	different	JJ
cord-010027-r0tl01kq	638	13	or	or	CC
cord-010027-r0tl01kq	638	14	heterogeneous	heterogeneous	JJ
cord-010027-r0tl01kq	638	15	tumours	tumour	NNS
cord-010027-r0tl01kq	638	16	.	.	.
cord-010027-r0tl01kq	639	1	A	a	DT
cord-010027-r0tl01kq	639	2	few	few	JJ
cord-010027-r0tl01kq	639	3	cases	case	NNS
cord-010027-r0tl01kq	639	4	were	be	VBD
cord-010027-r0tl01kq	639	5	repeated	repeat	VBN
cord-010027-r0tl01kq	639	6	because	because	IN
cord-010027-r0tl01kq	639	7	of	of	IN
cord-010027-r0tl01kq	639	8	borderline	borderline	JJ
cord-010027-r0tl01kq	639	9	negative	negative	JJ
cord-010027-r0tl01kq	639	10	FISH	fish	NN
cord-010027-r0tl01kq	639	11	results	result	NNS
cord-010027-r0tl01kq	639	12	or	or	CC
cord-010027-r0tl01kq	639	13	neoadjuvant	neoadjuvant	JJ
cord-010027-r0tl01kq	639	14	therapy	therapy	NN
cord-010027-r0tl01kq	639	15	.	.	.
cord-010027-r0tl01kq	640	1	18	18	CD
cord-010027-r0tl01kq	640	2	cases	case	NNS
cord-010027-r0tl01kq	640	3	were	be	VBD
cord-010027-r0tl01kq	640	4	repeated	repeat	VBN
cord-010027-r0tl01kq	640	5	due	due	IN
cord-010027-r0tl01kq	640	6	to	to	IN
cord-010027-r0tl01kq	640	7	insufficient	insufficient	JJ
cord-010027-r0tl01kq	640	8	tumour	tumour	NN
cord-010027-r0tl01kq	640	9	in	in	IN
cord-010027-r0tl01kq	640	10	the	the	DT
cord-010027-r0tl01kq	640	11	core	core	NN
cord-010027-r0tl01kq	640	12	biopsy	biopsy	NN
cord-010027-r0tl01kq	640	13	.	.	.
cord-010027-r0tl01kq	641	1	In	in	IN
cord-010027-r0tl01kq	641	2	this	this	DT
cord-010027-r0tl01kq	641	3	study	study	NN
cord-010027-r0tl01kq	641	4	the	the	DT
cord-010027-r0tl01kq	641	5	HER2	HER2	NNP
cord-010027-r0tl01kq	641	6	status	status	NN
cord-010027-r0tl01kq	641	7	of	of	IN
cord-010027-r0tl01kq	641	8	the	the	DT
cord-010027-r0tl01kq	641	9	index	index	NN
cord-010027-r0tl01kq	641	10	tumour	tumour	NN
cord-010027-r0tl01kq	641	11	was	be	VBD
cord-010027-r0tl01kq	641	12	changed	change	VBN
cord-010027-r0tl01kq	641	13	in	in	IN
cord-010027-r0tl01kq	641	14	2	2	CD
cord-010027-r0tl01kq	641	15	cases	case	NNS
cord-010027-r0tl01kq	641	16	and	and	CC
cord-010027-r0tl01kq	641	17	both	both	DT
cord-010027-r0tl01kq	641	18	were	be	VBD
cord-010027-r0tl01kq	641	19	in	in	IN
cord-010027-r0tl01kq	641	20	the	the	DT
cord-010027-r0tl01kq	641	21	borderline	borderline	JJ
cord-010027-r0tl01kq	641	22	result	result	NN
cord-010027-r0tl01kq	641	23	category	category	NN
cord-010027-r0tl01kq	641	24	.	.	.
cord-010027-r0tl01kq	642	1	HER2	her2	JJ
cord-010027-r0tl01kq	642	2	testing	testing	NN
cord-010027-r0tl01kq	642	3	of	of	IN
cord-010027-r0tl01kq	642	4	different	different	JJ
cord-010027-r0tl01kq	642	5	tumour	tumour	NN
cord-010027-r0tl01kq	642	6	foci	foci	NN
cord-010027-r0tl01kq	642	7	of	of	IN
cord-010027-r0tl01kq	642	8	multifocal	multifocal	JJ
cord-010027-r0tl01kq	642	9	or	or	CC
cord-010027-r0tl01kq	642	10	morphological	morphological	JJ
cord-010027-r0tl01kq	642	11	heterogeneous	heterogeneous	JJ
cord-010027-r0tl01kq	642	12	tumours	tumour	NNS
cord-010027-r0tl01kq	642	13	was	be	VBD
cord-010027-r0tl01kq	642	14	consistent	consistent	JJ
cord-010027-r0tl01kq	642	15	with	with	IN
cord-010027-r0tl01kq	642	16	that	that	DT
cord-010027-r0tl01kq	642	17	of	of	IN
cord-010027-r0tl01kq	642	18	the	the	DT
cord-010027-r0tl01kq	642	19	index	index	NN
cord-010027-r0tl01kq	642	20	tumour	tumour	NN
cord-010027-r0tl01kq	642	21	assessed	assess	VBN
cord-010027-r0tl01kq	642	22	on	on	IN
cord-010027-r0tl01kq	642	23	the	the	DT
cord-010027-r0tl01kq	642	24	core	core	NN
cord-010027-r0tl01kq	642	25	biopsy	biopsy	NN
cord-010027-r0tl01kq	642	26	apart	apart	RB
cord-010027-r0tl01kq	642	27	from	from	IN
cord-010027-r0tl01kq	642	28	two	two	CD
cord-010027-r0tl01kq	642	29	cases	case	NNS
cord-010027-r0tl01kq	642	30	;	;	:
cord-010027-r0tl01kq	642	31	one	one	CD
cord-010027-r0tl01kq	642	32	positive	positive	JJ
cord-010027-r0tl01kq	642	33	and	and	CC
cord-010027-r0tl01kq	642	34	one	one	CD
cord-010027-r0tl01kq	642	35	negative	negative	JJ
cord-010027-r0tl01kq	642	36	.	.	.
cord-010027-r0tl01kq	643	1	17	17	CD
cord-010027-r0tl01kq	643	2	tumours	tumour	NNS
cord-010027-r0tl01kq	643	3	were	be	VBD
cord-010027-r0tl01kq	643	4	upgraded	upgrade	VBN
cord-010027-r0tl01kq	643	5	from	from	IN
cord-010027-r0tl01kq	643	6	grade	grade	NN
cord-010027-r0tl01kq	643	7	2	2	CD
cord-010027-r0tl01kq	643	8	on	on	IN
cord-010027-r0tl01kq	643	9	core	core	NN
cord-010027-r0tl01kq	643	10	to	to	IN
cord-010027-r0tl01kq	643	11	grade	grade	NN
cord-010027-r0tl01kq	643	12	3	3	CD
cord-010027-r0tl01kq	643	13	on	on	IN
cord-010027-r0tl01kq	643	14	excision	excision	NN
cord-010027-r0tl01kq	643	15	and	and	CC
cord-010027-r0tl01kq	643	16	HER2	HER2	NNP
cord-010027-r0tl01kq	643	17	status	status	NN
cord-010027-r0tl01kq	643	18	did	do	VBD
cord-010027-r0tl01kq	643	19	not	not	RB
cord-010027-r0tl01kq	643	20	change	change	VB
cord-010027-r0tl01kq	643	21	.	.	.
cord-010027-r0tl01kq	644	1	No	no	DT
cord-010027-r0tl01kq	644	2	contribution	contribution	NN
cord-010027-r0tl01kq	644	3	of	of	IN
cord-010027-r0tl01kq	644	4	hormone	hormone	NN
cord-010027-r0tl01kq	644	5	receptor	receptor	NN
cord-010027-r0tl01kq	644	6	or	or	CC
cord-010027-r0tl01kq	644	7	tumour	tumour	NN
cord-010027-r0tl01kq	644	8	type	type	NN
cord-010027-r0tl01kq	644	9	was	be	VBD
cord-010027-r0tl01kq	644	10	identified	identify	VBN
cord-010027-r0tl01kq	644	11	.	.	.
cord-010027-r0tl01kq	645	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	645	2	:	:	:
cord-010027-r0tl01kq	645	3	There	there	EX
cord-010027-r0tl01kq	645	4	is	be	VBZ
cord-010027-r0tl01kq	645	5	excellent	excellent	JJ
cord-010027-r0tl01kq	645	6	agreement	agreement	NN
cord-010027-r0tl01kq	645	7	between	between	IN
cord-010027-r0tl01kq	645	8	HER2	HER2	NNP
cord-010027-r0tl01kq	645	9	assessed	assess	VBN
cord-010027-r0tl01kq	645	10	in	in	IN
cord-010027-r0tl01kq	645	11	core	core	NN
cord-010027-r0tl01kq	645	12	biopsy	biopsy	NN
cord-010027-r0tl01kq	645	13	and	and	CC
cord-010027-r0tl01kq	645	14	RS	rs	NN
cord-010027-r0tl01kq	645	15	.	.	.
cord-010027-r0tl01kq	646	1	Histopathological	Histopathological	NNP
cord-010027-r0tl01kq	646	2	discordance	discordance	NN
cord-010027-r0tl01kq	646	3	seems	seem	VBZ
cord-010027-r0tl01kq	646	4	to	to	TO
cord-010027-r0tl01kq	646	5	play	play	VB
cord-010027-r0tl01kq	646	6	a	a	DT
cord-010027-r0tl01kq	646	7	minor	minor	JJ
cord-010027-r0tl01kq	646	8	role	role	NN
cord-010027-r0tl01kq	646	9	which	which	WDT
cord-010027-r0tl01kq	646	10	does	do	VBZ
cord-010027-r0tl01kq	646	11	not	not	RB
cord-010027-r0tl01kq	646	12	justify	justify	VB
cord-010027-r0tl01kq	646	13	test	test	NN
cord-010027-r0tl01kq	646	14	repeat	repeat	NN
cord-010027-r0tl01kq	646	15	in	in	IN
cord-010027-r0tl01kq	646	16	routine	routine	JJ
cord-010027-r0tl01kq	646	17	practice	practice	NN
cord-010027-r0tl01kq	646	18	.	.	.
cord-010027-r0tl01kq	647	1	Tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	647	2	prevents	prevent	VBZ
cord-010027-r0tl01kq	647	3	breast	breast	NN
cord-010027-r0tl01kq	647	4	cancer	cancer	NN
cord-010027-r0tl01kq	647	5	in	in	IN
cord-010027-r0tl01kq	647	6	a	a	DT
cord-010027-r0tl01kq	647	7	sub	sub	JJ
cord-010027-r0tl01kq	647	8	-	-	JJ
cord-010027-r0tl01kq	647	9	set	set	VBN
cord-010027-r0tl01kq	647	10	of	of	IN
cord-010027-r0tl01kq	647	11	high	high	JJ
cord-010027-r0tl01kq	647	12	-	-	HYPH
cord-010027-r0tl01kq	647	13	risk	risk	NN
cord-010027-r0tl01kq	647	14	women	woman	NNS
cord-010027-r0tl01kq	647	15	in	in	IN
cord-010027-r0tl01kq	647	16	a	a	DT
cord-010027-r0tl01kq	647	17	mechanism	mechanism	NN
cord-010027-r0tl01kq	647	18	that	that	WDT
cord-010027-r0tl01kq	647	19	appears	appear	VBZ
cord-010027-r0tl01kq	647	20	to	to	TO
cord-010027-r0tl01kq	647	21	be	be	VB
cord-010027-r0tl01kq	647	22	dependent	dependent	JJ
cord-010027-r0tl01kq	647	23	on	on	IN
cord-010027-r0tl01kq	647	24	reduction	reduction	NN
cord-010027-r0tl01kq	647	25	of	of	IN
cord-010027-r0tl01kq	647	26	MD	MD	NNP
cord-010027-r0tl01kq	647	27	.	.	.
cord-010027-r0tl01kq	648	1	Animal	animal	NN
cord-010027-r0tl01kq	648	2	model	model	NN
cord-010027-r0tl01kq	648	3	studies	study	NNS
cord-010027-r0tl01kq	648	4	suggest	suggest	VBP
cord-010027-r0tl01kq	648	5	that	that	IN
cord-010027-r0tl01kq	648	6	tamoxifen	tamoxifen	NNP
cord-010027-r0tl01kq	648	7	remodels	remodel	VBZ
cord-010027-r0tl01kq	648	8	the	the	DT
cord-010027-r0tl01kq	648	9	mammary	mammary	JJ
cord-010027-r0tl01kq	648	10	stroma	stroma	NN
cord-010027-r0tl01kq	648	11	to	to	IN
cord-010027-r0tl01kq	648	12	a	a	DT
cord-010027-r0tl01kq	648	13	tumour	tumour	NN
cord-010027-r0tl01kq	648	14	-	-	HYPH
cord-010027-r0tl01kq	648	15	inhibitory	inhibitory	JJ
cord-010027-r0tl01kq	648	16	phenotype	phenotype	NN
cord-010027-r0tl01kq	648	17	.	.	.
cord-010027-r0tl01kq	649	1	This	this	DT
cord-010027-r0tl01kq	649	2	study	study	NN
cord-010027-r0tl01kq	649	3	aims	aim	VBZ
cord-010027-r0tl01kq	649	4	to	to	TO
cord-010027-r0tl01kq	649	5	analyse	analyse	VB
cord-010027-r0tl01kq	649	6	the	the	DT
cord-010027-r0tl01kq	649	7	effect	effect	NN
cord-010027-r0tl01kq	649	8	of	of	IN
cord-010027-r0tl01kq	649	9	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	649	10	on	on	IN
cord-010027-r0tl01kq	649	11	breast	breast	NN
cord-010027-r0tl01kq	649	12	fibroblast	fibroblast	NN
cord-010027-r0tl01kq	649	13	function	function	NN
cord-010027-r0tl01kq	649	14	and	and	CC
cord-010027-r0tl01kq	649	15	identify	identify	VB
cord-010027-r0tl01kq	649	16	potential	potential	JJ
cord-010027-r0tl01kq	649	17	protumourigenic	protumourigenic	JJ
cord-010027-r0tl01kq	649	18	pathways	pathway	NNS
cord-010027-r0tl01kq	649	19	contributing	contribute	VBG
cord-010027-r0tl01kq	649	20	to	to	IN
cord-010027-r0tl01kq	649	21	density	density	NN
cord-010027-r0tl01kq	649	22	-	-	HYPH
cord-010027-r0tl01kq	649	23	associated	associate	VBN
cord-010027-r0tl01kq	649	24	risk	risk	NN
cord-010027-r0tl01kq	649	25	.	.	.
cord-010027-r0tl01kq	650	1	Methods	method	NNS
cord-010027-r0tl01kq	650	2	:	:	:
cord-010027-r0tl01kq	650	3	Primary	primary	JJ
cord-010027-r0tl01kq	650	4	human	human	JJ
cord-010027-r0tl01kq	650	5	breast	breast	NN
cord-010027-r0tl01kq	650	6	fibroblasts	fibroblast	NNS
cord-010027-r0tl01kq	650	7	were	be	VBD
cord-010027-r0tl01kq	650	8	treated	treat	VBN
cord-010027-r0tl01kq	650	9	with	with	IN
cord-010027-r0tl01kq	650	10	hydroxytamoxifen	hydroxytamoxifen	NN
cord-010027-r0tl01kq	650	11	(	(	-LRB-
cord-010027-r0tl01kq	650	12	100nm-5µM	100nm-5µm	CD
cord-010027-r0tl01kq	650	13	)	)	-RRB-
cord-010027-r0tl01kq	650	14	.	.	.
cord-010027-r0tl01kq	651	1	Fibroblast	Fibroblast	NNP
cord-010027-r0tl01kq	651	2	function	function	NN
cord-010027-r0tl01kq	651	3	was	be	VBD
cord-010027-r0tl01kq	651	4	analysed	analyse	VBN
cord-010027-r0tl01kq	651	5	by	by	IN
cord-010027-r0tl01kq	651	6	measuring	measure	VBG
cord-010027-r0tl01kq	651	7	:	:	:
cord-010027-r0tl01kq	651	8	proliferation	proliferation	NN
cord-010027-r0tl01kq	651	9	;	;	:
cord-010027-r0tl01kq	651	10	expression	expression	NN
cord-010027-r0tl01kq	651	11	of	of	IN
cord-010027-r0tl01kq	651	12	stromal	stromal	JJ
cord-010027-r0tl01kq	651	13	proteins	protein	NNS
cord-010027-r0tl01kq	651	14	fibronectin	fibronectin	NN
cord-010027-r0tl01kq	651	15	(	(	-LRB-
cord-010027-r0tl01kq	651	16	FN	FN	NNP
cord-010027-r0tl01kq	651	17	)	)	-RRB-
cord-010027-r0tl01kq	651	18	,	,	,
cord-010027-r0tl01kq	651	19	LOX	LOX	NNP
cord-010027-r0tl01kq	651	20	and	and	CC
cord-010027-r0tl01kq	651	21	collagen	collagen	NN
cord-010027-r0tl01kq	651	22	1	1	CD
cord-010027-r0tl01kq	651	23	;	;	:
cord-010027-r0tl01kq	651	24	effects	effect	NNS
cord-010027-r0tl01kq	651	25	on	on	IN
cord-010027-r0tl01kq	651	26	TGF	TGF	NNP
cord-010027-r0tl01kq	651	27	-	-	HYPH
cord-010027-r0tl01kq	651	28	β	β	NN
cord-010027-r0tl01kq	651	29	signalling	signal	VBG
cord-010027-r0tl01kq	651	30	via	via	IN
cord-010027-r0tl01kq	651	31	SMAD	smad	JJ
cord-010027-r0tl01kq	651	32	phosphorylation	phosphorylation	NN
cord-010027-r0tl01kq	651	33	and	and	CC
cord-010027-r0tl01kq	651	34	upregulation	upregulation	NN
cord-010027-r0tl01kq	651	35	of	of	IN
cord-010027-r0tl01kq	651	36	the	the	DT
cord-010027-r0tl01kq	651	37	myofibroblast	myofibroblast	JJ
cord-010027-r0tl01kq	651	38	marker	marker	NN
cord-010027-r0tl01kq	651	39	SMA	SMA	NNP
cord-010027-r0tl01kq	651	40	.	.	.
cord-010027-r0tl01kq	652	1	Genome	genome	NN
cord-010027-r0tl01kq	652	2	wide	wide	JJ
cord-010027-r0tl01kq	652	3	analysis	analysis	NN
cord-010027-r0tl01kq	652	4	was	be	VBD
cord-010027-r0tl01kq	652	5	performed	perform	VBN
cord-010027-r0tl01kq	652	6	using	use	VBG
cord-010027-r0tl01kq	652	7	RNA	RNA	NNP
cord-010027-r0tl01kq	652	8	-	-	HYPH
cord-010027-r0tl01kq	652	9	Seq	Seq	NNP
cord-010027-r0tl01kq	652	10	.	.	.
cord-010027-r0tl01kq	653	1	Summary	summary	NN
cord-010027-r0tl01kq	653	2	of	of	IN
cord-010027-r0tl01kq	653	3	Results	result	NNS
cord-010027-r0tl01kq	653	4	:	:	:
cord-010027-r0tl01kq	654	1	Fibroblasts	fibroblast	NNS
cord-010027-r0tl01kq	654	2	from	from	IN
cord-010027-r0tl01kq	654	3	25	25	CD
cord-010027-r0tl01kq	654	4	patients	patient	NNS
cord-010027-r0tl01kq	654	5	were	be	VBD
cord-010027-r0tl01kq	654	6	treated	treat	VBN
cord-010027-r0tl01kq	654	7	with	with	IN
cord-010027-r0tl01kq	654	8	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	654	9	.	.	.
cord-010027-r0tl01kq	655	1	All	all	DT
cord-010027-r0tl01kq	655	2	patients	patient	NNS
cord-010027-r0tl01kq	655	3	showed	show	VBD
cord-010027-r0tl01kq	655	4	reduced	reduced	JJ
cord-010027-r0tl01kq	655	5	proliferation	proliferation	NN
cord-010027-r0tl01kq	655	6	with	with	IN
cord-010027-r0tl01kq	655	7	treatment	treatment	NN
cord-010027-r0tl01kq	655	8	.	.	.
cord-010027-r0tl01kq	656	1	In	in	IN
cord-010027-r0tl01kq	656	2	62	62	CD
cord-010027-r0tl01kq	656	3	%	%	NN
cord-010027-r0tl01kq	656	4	of	of	IN
cord-010027-r0tl01kq	656	5	patients	patient	NNS
cord-010027-r0tl01kq	656	6	tamoxifen	tamoxifen	NNP
cord-010027-r0tl01kq	656	7	treatment	treatment	NN
cord-010027-r0tl01kq	656	8	resulted	result	VBD
cord-010027-r0tl01kq	656	9	in	in	IN
cord-010027-r0tl01kq	656	10	reduced	reduce	VBN
cord-010027-r0tl01kq	656	11	expression	expression	NN
cord-010027-r0tl01kq	656	12	of	of	IN
cord-010027-r0tl01kq	656	13	FN	FN	NNP
cord-010027-r0tl01kq	656	14	.	.	.
cord-010027-r0tl01kq	657	1	TGF	TGF	NNP
cord-010027-r0tl01kq	657	2	-	-	HYPH
cord-010027-r0tl01kq	657	3	β	β	NN
cord-010027-r0tl01kq	657	4	-	-	HYPH
cord-010027-r0tl01kq	657	5	mediated	mediate	VBN
cord-010027-r0tl01kq	657	6	upregulation	upregulation	NN
cord-010027-r0tl01kq	657	7	of	of	IN
cord-010027-r0tl01kq	657	8	SMA	SMA	NNP
cord-010027-r0tl01kq	657	9	and	and	CC
cord-010027-r0tl01kq	657	10	FN	FN	NNP
cord-010027-r0tl01kq	657	11	were	be	VBD
cord-010027-r0tl01kq	657	12	consistently	consistently	RB
cord-010027-r0tl01kq	657	13	inhibited	inhibit	VBN
cord-010027-r0tl01kq	657	14	by	by	IN
cord-010027-r0tl01kq	657	15	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	657	16	,	,	,
cord-010027-r0tl01kq	657	17	as	as	IN
cord-010027-r0tl01kq	657	18	was	be	VBD
cord-010027-r0tl01kq	657	19	fibroblast	fibroblast	NN
cord-010027-r0tl01kq	657	20	contraction	contraction	NN
cord-010027-r0tl01kq	657	21	of	of	IN
cord-010027-r0tl01kq	657	22	collagen	collagen	NN
cord-010027-r0tl01kq	657	23	gels	gel	NNS
cord-010027-r0tl01kq	657	24	.	.	.
cord-010027-r0tl01kq	658	1	RNA	RNA	NNP
cord-010027-r0tl01kq	658	2	-	-	HYPH
cord-010027-r0tl01kq	658	3	Seq	Seq	NNP
cord-010027-r0tl01kq	658	4	analysis	analysis	NN
cord-010027-r0tl01kq	658	5	revealed	reveal	VBD
cord-010027-r0tl01kq	658	6	modulation	modulation	NN
cord-010027-r0tl01kq	658	7	of	of	IN
cord-010027-r0tl01kq	658	8	a	a	DT
cord-010027-r0tl01kq	658	9	number	number	NN
cord-010027-r0tl01kq	658	10	of	of	IN
cord-010027-r0tl01kq	658	11	metabolic	metabolic	JJ
cord-010027-r0tl01kq	658	12	pathways	pathway	NNS
cord-010027-r0tl01kq	658	13	by	by	IN
cord-010027-r0tl01kq	658	14	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	658	15	,	,	,
cord-010027-r0tl01kq	658	16	including	include	VBG
cord-010027-r0tl01kq	658	17	significant	significant	JJ
cord-010027-r0tl01kq	658	18	upregulation	upregulation	NN
cord-010027-r0tl01kq	658	19	of	of	IN
cord-010027-r0tl01kq	658	20	DHCR7	dhcr7	NN
cord-010027-r0tl01kq	658	21	,	,	,
cord-010027-r0tl01kq	658	22	part	part	NN
cord-010027-r0tl01kq	658	23	of	of	IN
cord-010027-r0tl01kq	658	24	the	the	DT
cord-010027-r0tl01kq	658	25	microsomal	microsomal	NNP
cord-010027-r0tl01kq	658	26	antioestrogen	antioestrogen	NNP
cord-010027-r0tl01kq	658	27	binding	bind	VBG
cord-010027-r0tl01kq	658	28	site	site	NN
cord-010027-r0tl01kq	658	29	(	(	-LRB-
cord-010027-r0tl01kq	658	30	AEBS	AEBS	NNP
cord-010027-r0tl01kq	658	31	)	)	-RRB-
cord-010027-r0tl01kq	658	32	.	.	.
cord-010027-r0tl01kq	659	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	659	2	:	:	:
cord-010027-r0tl01kq	660	1	These	these	DT
cord-010027-r0tl01kq	660	2	data	datum	NNS
cord-010027-r0tl01kq	660	3	indicate	indicate	VBP
cord-010027-r0tl01kq	660	4	that	that	IN
cord-010027-r0tl01kq	660	5	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	660	6	can	can	MD
cord-010027-r0tl01kq	660	7	directly	directly	RB
cord-010027-r0tl01kq	660	8	remodel	remodel	VB
cord-010027-r0tl01kq	660	9	the	the	DT
cord-010027-r0tl01kq	660	10	stromal	stromal	JJ
cord-010027-r0tl01kq	660	11	microenvironment	microenvironment	NN
cord-010027-r0tl01kq	660	12	,	,	,
cord-010027-r0tl01kq	660	13	generating	generate	VBG
cord-010027-r0tl01kq	660	14	a	a	DT
cord-010027-r0tl01kq	660	15	less	less	RBR
cord-010027-r0tl01kq	660	16	'	'	``
cord-010027-r0tl01kq	660	17	reactive	reactive	JJ
cord-010027-r0tl01kq	660	18	'	'	''
cord-010027-r0tl01kq	660	19	stroma	stroma	NN
cord-010027-r0tl01kq	660	20	.	.	.
cord-010027-r0tl01kq	661	1	Modulation	modulation	NN
cord-010027-r0tl01kq	661	2	of	of	IN
cord-010027-r0tl01kq	661	3	AEBS	AEBS	NNP
cord-010027-r0tl01kq	661	4	activity	activity	NN
cord-010027-r0tl01kq	661	5	has	have	VBZ
cord-010027-r0tl01kq	661	6	been	be	VBN
cord-010027-r0tl01kq	661	7	proposed	propose	VBN
cord-010027-r0tl01kq	661	8	to	to	TO
cord-010027-r0tl01kq	661	9	be	be	VB
cord-010027-r0tl01kq	661	10	anti	anti	JJ
cord-010027-r0tl01kq	661	11	-	-	JJ
cord-010027-r0tl01kq	661	12	tumourigenic	tumourigenic	JJ
cord-010027-r0tl01kq	661	13	,	,	,
cord-010027-r0tl01kq	661	14	and	and	CC
cord-010027-r0tl01kq	661	15	also	also	RB
cord-010027-r0tl01kq	661	16	is	be	VBZ
cord-010027-r0tl01kq	661	17	implicated	implicate	VBN
cord-010027-r0tl01kq	661	18	as	as	IN
cord-010027-r0tl01kq	661	19	a	a	DT
cord-010027-r0tl01kq	661	20	suppressor	suppressor	NN
cord-010027-r0tl01kq	661	21	of	of	IN
cord-010027-r0tl01kq	661	22	Hedgehog	Hedgehog	NNP
cord-010027-r0tl01kq	661	23	signalling	signalling	NN
cord-010027-r0tl01kq	661	24	.	.	.
cord-010027-r0tl01kq	662	1	Thus	thus	RB
cord-010027-r0tl01kq	662	2	,	,	,
cord-010027-r0tl01kq	662	3	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	662	4	impacts	impact	NNS
cord-010027-r0tl01kq	662	5	on	on	IN
cord-010027-r0tl01kq	662	6	multiple	multiple	JJ
cord-010027-r0tl01kq	662	7	pathways	pathway	NNS
cord-010027-r0tl01kq	662	8	to	to	TO
cord-010027-r0tl01kq	662	9	create	create	VB
cord-010027-r0tl01kq	662	10	a	a	DT
cord-010027-r0tl01kq	662	11	tumour	tumour	NN
cord-010027-r0tl01kq	662	12	inhibitory	inhibitory	JJ
cord-010027-r0tl01kq	662	13	phenotype	phenotype	NN
cord-010027-r0tl01kq	662	14	.	.	.
cord-010027-r0tl01kq	663	1	This	this	DT
cord-010027-r0tl01kq	663	2	work	work	NN
cord-010027-r0tl01kq	663	3	was	be	VBD
cord-010027-r0tl01kq	663	4	supported	support	VBN
cord-010027-r0tl01kq	663	5	by	by	IN
cord-010027-r0tl01kq	663	6	the	the	DT
cord-010027-r0tl01kq	663	7	Pathsoc	Pathsoc	NNP
cord-010027-r0tl01kq	663	8	Small	Small	NNP
cord-010027-r0tl01kq	663	9	Grant	Grant	NNP
cord-010027-r0tl01kq	663	10	Scheme	Scheme	NNP
cord-010027-r0tl01kq	663	11	.	.	.
cord-010027-r0tl01kq	664	1	Purpose	purpose	NN
cord-010027-r0tl01kq	664	2	of	of	IN
cord-010027-r0tl01kq	664	3	the	the	DT
cord-010027-r0tl01kq	664	4	Study	Study	NNP
cord-010027-r0tl01kq	664	5	:	:	:
cord-010027-r0tl01kq	664	6	The	the	DT
cord-010027-r0tl01kq	664	7	Phenotypic	Phenotypic	NNP
cord-010027-r0tl01kq	664	8	features	feature	NNS
cord-010027-r0tl01kq	664	9	of	of	IN
cord-010027-r0tl01kq	664	10	basal	basal	NN
cord-010027-r0tl01kq	664	11	like	like	IN
cord-010027-r0tl01kq	664	12	(	(	-LRB-
cord-010027-r0tl01kq	664	13	BL	bl	NN
cord-010027-r0tl01kq	664	14	)	)	-RRB-
cord-010027-r0tl01kq	664	15	breast	breast	NN
cord-010027-r0tl01kq	664	16	cancer	cancer	NN
cord-010027-r0tl01kq	664	17	(	(	-LRB-
cord-010027-r0tl01kq	664	18	BC	BC	NNP
cord-010027-r0tl01kq	664	19	)	)	-RRB-
cord-010027-r0tl01kq	664	20	resemble	resemble	VBP
cord-010027-r0tl01kq	664	21	those	those	DT
cord-010027-r0tl01kq	664	22	occurring	occur	VBG
cord-010027-r0tl01kq	664	23	in	in	IN
cord-010027-r0tl01kq	664	24	BRCA1-germline	BRCA1-germline	NNP
cord-010027-r0tl01kq	664	25	mutation	mutation	NN
cord-010027-r0tl01kq	664	26	carriers	carrier	NNS
cord-010027-r0tl01kq	664	27	.	.	.
cord-010027-r0tl01kq	665	1	Several	several	JJ
cord-010027-r0tl01kq	665	2	lines	line	NNS
cord-010027-r0tl01kq	665	3	of	of	IN
cord-010027-r0tl01kq	665	4	evidence	evidence	NN
cord-010027-r0tl01kq	665	5	suggesting	suggest	VBG
cord-010027-r0tl01kq	665	6	the	the	DT
cord-010027-r0tl01kq	665	7	overall	overall	JJ
cord-010027-r0tl01kq	665	8	tendency	tendency	NN
cord-010027-r0tl01kq	665	9	of	of	IN
cord-010027-r0tl01kq	665	10	basal	basal	NN
cord-010027-r0tl01kq	665	11	-	-	HYPH
cord-010027-r0tl01kq	665	12	like	like	JJ
cord-010027-r0tl01kq	665	13	/	/	SYM
cord-010027-r0tl01kq	665	14	triple	triple	JJ
cord-010027-r0tl01kq	665	15	negative	negative	JJ
cord-010027-r0tl01kq	665	16	BC	BC	NNP
cord-010027-r0tl01kq	665	17	to	to	TO
cord-010027-r0tl01kq	665	18	spread	spread	VB
cord-010027-r0tl01kq	665	19	through	through	IN
cord-010027-r0tl01kq	665	20	vascular	vascular	JJ
cord-010027-r0tl01kq	665	21	rather	rather	RB
cord-010027-r0tl01kq	665	22	than	than	IN
cord-010027-r0tl01kq	665	23	lymphatic	lymphatic	JJ
cord-010027-r0tl01kq	665	24	routes	route	NNS
cord-010027-r0tl01kq	665	25	.	.	.
cord-010027-r0tl01kq	666	1	The	the	DT
cord-010027-r0tl01kq	666	2	latter	latter	NN
cord-010027-r0tl01kq	666	3	has	have	VBZ
cord-010027-r0tl01kq	666	4	recently	recently	RB
cord-010027-r0tl01kq	666	5	been	be	VBN
cord-010027-r0tl01kq	666	6	attributed	attribute	VBN
cord-010027-r0tl01kq	666	7	to	to	IN
cord-010027-r0tl01kq	666	8	the	the	DT
cord-010027-r0tl01kq	666	9	activation	activation	NN
cord-010027-r0tl01kq	666	10	of	of	IN
cord-010027-r0tl01kq	666	11	cadherin	cadherin	NN
cord-010027-r0tl01kq	666	12	switch	switch	NN
cord-010027-r0tl01kq	666	13	,	,	,
cord-010027-r0tl01kq	666	14	an	an	DT
cord-010027-r0tl01kq	666	15	EMT	EMT	NNP
cord-010027-r0tl01kq	666	16	-	-	HYPH
cord-010027-r0tl01kq	666	17	like	like	JJ
cord-010027-r0tl01kq	666	18	phenomenon	phenomenon	NN
cord-010027-r0tl01kq	666	19	,	,	,
cord-010027-r0tl01kq	666	20	in	in	IN
cord-010027-r0tl01kq	666	21	BLBC	BLBC	NNP
cord-010027-r0tl01kq	666	22	.	.	.
cord-010027-r0tl01kq	667	1	This	this	DT
cord-010027-r0tl01kq	667	2	study	study	NN
cord-010027-r0tl01kq	667	3	aims	aim	VBZ
cord-010027-r0tl01kq	667	4	at	at	IN
cord-010027-r0tl01kq	667	5	studying	study	VBG
cord-010027-r0tl01kq	667	6	the	the	DT
cord-010027-r0tl01kq	667	7	cadherin	cadherin	NN
cord-010027-r0tl01kq	667	8	switch	switch	NN
cord-010027-r0tl01kq	667	9	expression	expression	NN
cord-010027-r0tl01kq	667	10	profile	profile	NN
cord-010027-r0tl01kq	667	11	TGFB1	TGFB1	NNP
cord-010027-r0tl01kq	667	12	,	,	,
cord-010027-r0tl01kq	667	13	a	a	DT
cord-010027-r0tl01kq	667	14	key	key	JJ
cord-010027-r0tl01kq	667	15	EMT	EMT	NNP
cord-010027-r0tl01kq	667	16	-	-	HYPH
cord-010027-r0tl01kq	667	17	trigger	trigger	NN
cord-010027-r0tl01kq	667	18	,	,	,
cord-010027-r0tl01kq	667	19	expression	expression	NN
cord-010027-r0tl01kq	667	20	in	in	IN
cord-010027-r0tl01kq	667	21	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	667	22	mutated	mutate	VBN
cord-010027-r0tl01kq	667	23	compared	compare	VBN
cord-010027-r0tl01kq	667	24	to	to	IN
cord-010027-r0tl01kq	667	25	sporadic	sporadic	JJ
cord-010027-r0tl01kq	667	26	BC	BC	NNP
cord-010027-r0tl01kq	667	27	.	.	.
cord-010027-r0tl01kq	668	1	The	the	DT
cord-010027-r0tl01kq	668	2	expression	expression	NN
cord-010027-r0tl01kq	668	3	of	of	IN
cord-010027-r0tl01kq	668	4	E	e	NN
cord-010027-r0tl01kq	668	5	-	-	NN
cord-010027-r0tl01kq	668	6	cadherin	cadherin	NN
cord-010027-r0tl01kq	668	7	,	,	,
cord-010027-r0tl01kq	668	8	N	n	CD
cord-010027-r0tl01kq	668	9	-	-	HYPH
cord-010027-r0tl01kq	668	10	cadherin	cadherin	NN
cord-010027-r0tl01kq	668	11	and	and	CC
cord-010027-r0tl01kq	668	12	TGFB1	TGFB1	NNP
cord-010027-r0tl01kq	668	13	were	be	VBD
cord-010027-r0tl01kq	668	14	studied	study	VBN
cord-010027-r0tl01kq	668	15	in	in	IN
cord-010027-r0tl01kq	668	16	a	a	DT
cord-010027-r0tl01kq	668	17	subset	subset	NN
cord-010027-r0tl01kq	668	18	of	of	IN
cord-010027-r0tl01kq	668	19	germline	germline	JJ
cord-010027-r0tl01kq	668	20	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	668	21	mutated	mutate	VBN
cord-010027-r0tl01kq	668	22	BC	BC	NNP
cord-010027-r0tl01kq	668	23	(	(	-LRB-
cord-010027-r0tl01kq	668	24	n=	n=	NNP
cord-010027-r0tl01kq	668	25	47	47	CD
cord-010027-r0tl01kq	668	26	)	)	-RRB-
cord-010027-r0tl01kq	668	27	compared	compare	VBN
cord-010027-r0tl01kq	668	28	to	to	IN
cord-010027-r0tl01kq	668	29	non	non	JJ
cord-010027-r0tl01kq	668	30	-	-	JJ
cord-010027-r0tl01kq	668	31	selected	selected	JJ
cord-010027-r0tl01kq	668	32	cohorts	cohort	NNS
cord-010027-r0tl01kq	668	33	of	of	IN
cord-010027-r0tl01kq	668	34	non	non	JJ
cord-010027-r0tl01kq	668	35	-	-	JJ
cord-010027-r0tl01kq	668	36	lobular	lobular	JJ
cord-010027-r0tl01kq	668	37	sporadic	sporadic	JJ
cord-010027-r0tl01kq	668	38	invasive	invasive	JJ
cord-010027-r0tl01kq	668	39	BLBC	BLBC	NNP
cord-010027-r0tl01kq	669	1	(	(	-LRB-
cord-010027-r0tl01kq	669	2	n=	n=	NNP
cord-010027-r0tl01kq	669	3	422	422	CD
cord-010027-r0tl01kq	669	4	)	)	-RRB-
cord-010027-r0tl01kq	669	5	and	and	CC
cord-010027-r0tl01kq	669	6	non	non	JJ
cord-010027-r0tl01kq	669	7	-	-	JJ
cord-010027-r0tl01kq	669	8	basal	basal	JJ
cord-010027-r0tl01kq	669	9	BC	BC	NNP
cord-010027-r0tl01kq	669	10	(	(	-LRB-
cord-010027-r0tl01kq	669	11	n=1190	n=1190	CD
cord-010027-r0tl01kq	669	12	)	)	-RRB-
cord-010027-r0tl01kq	670	1	using	use	VBG
cord-010027-r0tl01kq	670	2	IHC	IHC	NNP
cord-010027-r0tl01kq	670	3	and	and	CC
cord-010027-r0tl01kq	670	4	TMA	TMA	NNP
cord-010027-r0tl01kq	670	5	.	.	.
cord-010027-r0tl01kq	671	1	Summary	summary	NN
cord-010027-r0tl01kq	671	2	of	of	IN
cord-010027-r0tl01kq	671	3	results	result	NNS
cord-010027-r0tl01kq	671	4	:	:	:
cord-010027-r0tl01kq	672	1	Compared	compare	VBN
cord-010027-r0tl01kq	672	2	to	to	IN
cord-010027-r0tl01kq	672	3	sporadic	sporadic	JJ
cord-010027-r0tl01kq	672	4	BC	BC	NNP
cord-010027-r0tl01kq	672	5	,	,	,
cord-010027-r0tl01kq	672	6	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	672	7	mutated	mutate	VBN
cord-010027-r0tl01kq	672	8	cases	case	NNS
cord-010027-r0tl01kq	672	9	were	be	VBD
cord-010027-r0tl01kq	672	10	of	of	IN
cord-010027-r0tl01kq	672	11	younger	young	JJR
cord-010027-r0tl01kq	672	12	age	age	NN
cord-010027-r0tl01kq	672	13	,	,	,
cord-010027-r0tl01kq	672	14	more	more	JJR
cord-010027-r0tl01kq	672	15	grade	grade	NN
cord-010027-r0tl01kq	672	16	3	3	CD
cord-010027-r0tl01kq	672	17	,	,	,
cord-010027-r0tl01kq	672	18	with	with	IN
cord-010027-r0tl01kq	672	19	more	more	JJR
cord-010027-r0tl01kq	672	20	medullary	medullary	JJ
cord-010027-r0tl01kq	672	21	-	-	HYPH
cord-010027-r0tl01kq	672	22	like	like	JJ
cord-010027-r0tl01kq	672	23	tumours	tumour	NNS
cord-010027-r0tl01kq	672	24	,	,	,
cord-010027-r0tl01kq	672	25	and	and	CC
cord-010027-r0tl01kq	672	26	more	more	JJR
cord-010027-r0tl01kq	672	27	LVI	LVI	NNP
cord-010027-r0tl01kq	672	28	positive	positive	JJ
cord-010027-r0tl01kq	672	29	.	.	.
cord-010027-r0tl01kq	673	1	E	E	NNP
cord-010027-r0tl01kq	673	2	-	-	NN
cord-010027-r0tl01kq	673	3	cad	cad	NNP
cord-010027-r0tl01kq	673	4	was	be	VBD
cord-010027-r0tl01kq	673	5	significantly	significantly	RB
cord-010027-r0tl01kq	673	6	less	less	RBR
cord-010027-r0tl01kq	673	7	expressed	express	VBN
cord-010027-r0tl01kq	673	8	in	in	IN
cord-010027-r0tl01kq	673	9	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	673	10	cases	case	NNS
cord-010027-r0tl01kq	673	11	than	than	IN
cord-010027-r0tl01kq	673	12	in	in	IN
cord-010027-r0tl01kq	673	13	the	the	DT
cord-010027-r0tl01kq	673	14	sporadic	sporadic	JJ
cord-010027-r0tl01kq	673	15	non	non	JJ
cord-010027-r0tl01kq	673	16	-	-	JJ
cord-010027-r0tl01kq	673	17	basal	basal	JJ
cord-010027-r0tl01kq	673	18	and	and	CC
cord-010027-r0tl01kq	673	19	in	in	IN
cord-010027-r0tl01kq	673	20	the	the	DT
cord-010027-r0tl01kq	673	21	BLBC	BLBC	NNP
cord-010027-r0tl01kq	673	22	.	.	.
cord-010027-r0tl01kq	674	1	However	however	RB
cord-010027-r0tl01kq	674	2	,	,	,
cord-010027-r0tl01kq	674	3	N	N	NNP
cord-010027-r0tl01kq	674	4	-	-	HYPH
cord-010027-r0tl01kq	674	5	cad	cad	NNP
cord-010027-r0tl01kq	674	6	was	be	VBD
cord-010027-r0tl01kq	674	7	not	not	RB
cord-010027-r0tl01kq	674	8	significantly	significantly	RB
cord-010027-r0tl01kq	674	9	expressed	express	VBN
cord-010027-r0tl01kq	674	10	in	in	IN
cord-010027-r0tl01kq	674	11	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	674	12	,	,	,
cord-010027-r0tl01kq	674	13	non	non	JJ
cord-010027-r0tl01kq	674	14	-	-	JJ
cord-010027-r0tl01kq	674	15	basal	basal	JJ
cord-010027-r0tl01kq	674	16	,	,	,
cord-010027-r0tl01kq	674	17	and	and	CC
cord-010027-r0tl01kq	674	18	BLBC	BLBC	NNP
cord-010027-r0tl01kq	674	19	.	.	.
cord-010027-r0tl01kq	675	1	TGFB1	TGFB1	NNP
cord-010027-r0tl01kq	675	2	was	be	VBD
cord-010027-r0tl01kq	675	3	significantly	significantly	RB
cord-010027-r0tl01kq	675	4	less	less	RBR
cord-010027-r0tl01kq	675	5	expressed	express	VBN
cord-010027-r0tl01kq	675	6	in	in	IN
cord-010027-r0tl01kq	675	7	sporadic	sporadic	JJ
cord-010027-r0tl01kq	675	8	BC	BC	NNP
cord-010027-r0tl01kq	675	9	,	,	,
cord-010027-r0tl01kq	675	10	both	both	CC
cord-010027-r0tl01kq	675	11	non	non	JJ
cord-010027-r0tl01kq	675	12	-	-	JJ
cord-010027-r0tl01kq	675	13	basal	basal	JJ
cord-010027-r0tl01kq	675	14	BLBC	BLBC	NNP
cord-010027-r0tl01kq	675	15	than	than	IN
cord-010027-r0tl01kq	675	16	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	675	17	mutated	mutate	VBN
cord-010027-r0tl01kq	675	18	BC	BC	NNP
cord-010027-r0tl01kq	675	19	.	.	.
cord-010027-r0tl01kq	676	1	E	e	JJ
cord-010027-r0tl01kq	676	2	-	-	JJ
cord-010027-r0tl01kq	676	3	cad	cad	NNP
cord-010027-r0tl01kq	676	4	/	/	SYM
cord-010027-r0tl01kq	676	5	N	N	NNP
cord-010027-r0tl01kq	676	6	-	-	HYPH
cord-010027-r0tl01kq	676	7	cad	cad	JJ
cord-010027-r0tl01kq	676	8	combinatorial	combinatorial	JJ
cord-010027-r0tl01kq	676	9	expression	expression	NN
cord-010027-r0tl01kq	676	10	phenotypes	phenotype	NNS
cord-010027-r0tl01kq	676	11	were	be	VBD
cord-010027-r0tl01kq	676	12	significantly	significantly	RB
cord-010027-r0tl01kq	676	13	different	different	JJ
cord-010027-r0tl01kq	676	14	between	between	IN
cord-010027-r0tl01kq	676	15	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	676	16	mutated	mutate	VBN
cord-010027-r0tl01kq	676	17	and	and	CC
cord-010027-r0tl01kq	676	18	non	non	JJ
cord-010027-r0tl01kq	676	19	-	-	JJ
cord-010027-r0tl01kq	676	20	basal	basal	JJ
cord-010027-r0tl01kq	676	21	and	and	CC
cord-010027-r0tl01kq	676	22	BLBC	BLBC	NNP
cord-010027-r0tl01kq	676	23	.	.	.
cord-010027-r0tl01kq	677	1	Higher	high	JJR
cord-010027-r0tl01kq	677	2	proportions	proportion	NNS
cord-010027-r0tl01kq	677	3	E	e	NN
cord-010027-r0tl01kq	677	4	-	-	NN
cord-010027-r0tl01kq	677	5	cad-/N	cad-/n	NN
cord-010027-r0tl01kq	677	6	-	-	:
cord-010027-r0tl01kq	677	7	cad+	cad+	NNP
cord-010027-r0tl01kq	677	8	were	be	VBD
cord-010027-r0tl01kq	677	9	significantly	significantly	RB
cord-010027-r0tl01kq	677	10	observed	observe	VBN
cord-010027-r0tl01kq	677	11	BLBC	BLBC	NNP
cord-010027-r0tl01kq	677	12	than	than	IN
cord-010027-r0tl01kq	677	13	non	non	JJ
cord-010027-r0tl01kq	677	14	-	-	JJ
cord-010027-r0tl01kq	677	15	basal	basal	JJ
cord-010027-r0tl01kq	677	16	BC	BC	NNP
cord-010027-r0tl01kq	677	17	.	.	.
cord-010027-r0tl01kq	678	1	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	678	2	mutated	mutate	VBN
cord-010027-r0tl01kq	678	3	cases	case	NNS
cord-010027-r0tl01kq	678	4	displayed	display	VBD
cord-010027-r0tl01kq	678	5	the	the	DT
cord-010027-r0tl01kq	678	6	least	least	JJS
cord-010027-r0tl01kq	678	7	E	e	NN
cord-010027-r0tl01kq	678	8	-	-	HYPH
cord-010027-r0tl01kq	678	9	cad+	cad+	JJ
cord-010027-r0tl01kq	678	10	expression	expression	NN
cord-010027-r0tl01kq	678	11	and	and	CC
cord-010027-r0tl01kq	678	12	the	the	DT
cord-010027-r0tl01kq	678	13	highest	high	JJS
cord-010027-r0tl01kq	678	14	E	e	NN
cord-010027-r0tl01kq	678	15	-	-	NN
cord-010027-r0tl01kq	678	16	cad-/N	cad-/n	NN
cord-010027-r0tl01kq	678	17	-	-	:
cord-010027-r0tl01kq	678	18	cad+	cad+	NNP
cord-010027-r0tl01kq	678	19	in	in	IN
cord-010027-r0tl01kq	678	20	the	the	DT
cord-010027-r0tl01kq	678	21	studied	study	VBN
cord-010027-r0tl01kq	678	22	series	series	NN
cord-010027-r0tl01kq	678	23	.	.	.
cord-010027-r0tl01kq	679	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	679	2	:	:	:
cord-010027-r0tl01kq	680	1	Despite	despite	IN
cord-010027-r0tl01kq	680	2	the	the	DT
cord-010027-r0tl01kq	680	3	known	know	VBN
cord-010027-r0tl01kq	680	4	similarities	similarity	NNS
cord-010027-r0tl01kq	680	5	between	between	IN
cord-010027-r0tl01kq	680	6	BRCA	BRCA	NNP
cord-010027-r0tl01kq	680	7	mutated	mutate	VBN
cord-010027-r0tl01kq	680	8	and	and	CC
cord-010027-r0tl01kq	680	9	BLBC	BLBC	NNP
cord-010027-r0tl01kq	680	10	,	,	,
cord-010027-r0tl01kq	680	11	results	result	NNS
cord-010027-r0tl01kq	680	12	of	of	IN
cord-010027-r0tl01kq	680	13	this	this	DT
cord-010027-r0tl01kq	680	14	study	study	NN
cord-010027-r0tl01kq	680	15	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	680	16	the	the	DT
cord-010027-r0tl01kq	680	17	more	more	JJR
cord-010027-r0tl01kq	680	18	occurrence	occurrence	NN
cord-010027-r0tl01kq	680	19	of	of	IN
cord-010027-r0tl01kq	680	20	cadherin	cadherin	NN
cord-010027-r0tl01kq	680	21	switch	switch	NN
cord-010027-r0tl01kq	680	22	in	in	IN
cord-010027-r0tl01kq	680	23	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	680	24	mutated	mutate	VBN
cord-010027-r0tl01kq	680	25	breast	breast	NN
cord-010027-r0tl01kq	680	26	cancer	cancer	NN
cord-010027-r0tl01kq	680	27	.	.	.
cord-010027-r0tl01kq	681	1	E	e	JJ
cord-010027-r0tl01kq	681	2	-	-	JJ
cord-010027-r0tl01kq	681	3	cad	cad	JJ
cord-010027-r0tl01kq	681	4	repression	repression	NN
cord-010027-r0tl01kq	681	5	appears	appear	VBZ
cord-010027-r0tl01kq	681	6	to	to	TO
cord-010027-r0tl01kq	681	7	contribute	contribute	VB
cord-010027-r0tl01kq	681	8	more	more	JJR
cord-010027-r0tl01kq	681	9	than	than	IN
cord-010027-r0tl01kq	681	10	N	n	CD
cord-010027-r0tl01kq	681	11	-	-	HYPH
cord-010027-r0tl01kq	681	12	cad	cad	NN
cord-010027-r0tl01kq	681	13	gain	gain	NN
cord-010027-r0tl01kq	681	14	in	in	IN
cord-010027-r0tl01kq	681	15	BLBC	BLBC	NNP
cord-010027-r0tl01kq	681	16	than	than	IN
cord-010027-r0tl01kq	681	17	non	non	JJ
cord-010027-r0tl01kq	681	18	-	-	JJ
cord-010027-r0tl01kq	681	19	basal	basal	JJ
cord-010027-r0tl01kq	681	20	BC	BC	NNP
cord-010027-r0tl01kq	681	21	.	.	.
cord-010027-r0tl01kq	682	1	Exploring	explore	VBG
cord-010027-r0tl01kq	682	2	Molecular	Molecular	NNP
cord-010027-r0tl01kq	682	3	Mechanisms	Mechanisms	NNPS
cord-010027-r0tl01kq	682	4	Underlying	Underlying	NNP
cord-010027-r0tl01kq	682	5	Lymphovascular	Lymphovascular	NNP
cord-010027-r0tl01kq	682	6	Invasion	Invasion	NNP
cord-010027-r0tl01kq	682	7	in	in	IN
cord-010027-r0tl01kq	682	8	Breast	Breast	NNP
cord-010027-r0tl01kq	682	9	Cancer	Cancer	NNP
cord-010027-r0tl01kq	682	10	P	p	NN
cord-010027-r0tl01kq	682	11	SN	SN	NNP
cord-010027-r0tl01kq	682	12	Sonbul	Sonbul	NNP
cord-010027-r0tl01kq	682	13	1	1	CD
cord-010027-r0tl01kq	682	14	;	;	:
cord-010027-r0tl01kq	682	15	A	a	DT
cord-010027-r0tl01kq	682	16	Mukherjee	Mukherjee	NNP
cord-010027-r0tl01kq	682	17	1	1	CD
cord-010027-r0tl01kq	682	18	;	;	:
cord-010027-r0tl01kq	682	19	R	R	NNP
cord-010027-r0tl01kq	682	20	Russell	Russell	NNP
cord-010027-r0tl01kq	682	21	2	2	CD
cord-010027-r0tl01kq	682	22	;	;	:
cord-010027-r0tl01kq	682	23	OM	OM	NNP
cord-010027-r0tl01kq	682	24	Rueda	Rueda	NNP
cord-010027-r0tl01kq	682	25	2	2	CD
cord-010027-r0tl01kq	682	26	;	;	:
cord-010027-r0tl01kq	682	27	M	M	NNP
cord-010027-r0tl01kq	682	28	Aleskandarany	Aleskandarany	NNP
cord-010027-r0tl01kq	682	29	1	1	CD
cord-010027-r0tl01kq	682	30	;	;	:
cord-010027-r0tl01kq	682	31	AR	AR	NNP
cord-010027-r0tl01kq	682	32	Green	Green	NNP
cord-010027-r0tl01kq	682	33	1	1	CD
cord-010027-r0tl01kq	682	34	;	;	:
cord-010027-r0tl01kq	682	35	E	E	NNP
cord-010027-r0tl01kq	682	36	Provenzano	Provenzano	NNP
cord-010027-r0tl01kq	682	37	3	3	CD
cord-010027-r0tl01kq	682	38	;	;	:
cord-010027-r0tl01kq	682	39	C	C	NNP
cord-010027-r0tl01kq	682	40	Caldas	Caldas	NNP
cord-010027-r0tl01kq	682	41	3	3	CD
cord-010027-r0tl01kq	682	42	;	;	:
cord-010027-r0tl01kq	682	43	IO	IO	NNP
cord-010027-r0tl01kq	682	44	Ellis	Ellis	NNP
cord-010027-r0tl01kq	682	45	1	1	CD
cord-010027-r0tl01kq	682	46	;	;	:
cord-010027-r0tl01kq	682	47	EA	EA	NNP
cord-010027-r0tl01kq	682	48	Rakha	Rakha	NNP
cord-010027-r0tl01kq	682	49	1	1	CD
cord-010027-r0tl01kq	683	1	The	the	DT
cord-010027-r0tl01kq	683	2	development	development	NN
cord-010027-r0tl01kq	683	3	of	of	IN
cord-010027-r0tl01kq	683	4	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	683	5	resistance	resistance	NN
cord-010027-r0tl01kq	683	6	(	(	-LRB-
cord-010027-r0tl01kq	683	7	TR	TR	NNP
cord-010027-r0tl01kq	683	8	)	)	-RRB-
cord-010027-r0tl01kq	683	9	in	in	IN
cord-010027-r0tl01kq	683	10	oestrogen	oestrogen	NN
cord-010027-r0tl01kq	683	11	-	-	HYPH
cord-010027-r0tl01kq	683	12	dependent	dependent	JJ
cord-010027-r0tl01kq	683	13	breast	breast	NN
cord-010027-r0tl01kq	683	14	cancer	cancer	NN
cord-010027-r0tl01kq	683	15	(	(	-LRB-
cord-010027-r0tl01kq	683	16	BC	BC	NNP
cord-010027-r0tl01kq	683	17	)	)	-RRB-
cord-010027-r0tl01kq	683	18	is	be	VBZ
cord-010027-r0tl01kq	683	19	a	a	DT
cord-010027-r0tl01kq	683	20	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	683	21	challenge	challenge	NN
cord-010027-r0tl01kq	683	22	.	.	.
cord-010027-r0tl01kq	684	1	Insulin	insulin	NN
cord-010027-r0tl01kq	684	2	-	-	HYPH
cord-010027-r0tl01kq	684	3	like	like	JJ
cord-010027-r0tl01kq	684	4	growth	growth	NN
cord-010027-r0tl01kq	684	5	factor	factor	NN
cord-010027-r0tl01kq	684	6	binding	bind	VBG
cord-010027-r0tl01kq	684	7	proteins	protein	NNS
cord-010027-r0tl01kq	684	8	(	(	-LRB-
cord-010027-r0tl01kq	684	9	IGFBPs	igfbp	NNS
cord-010027-r0tl01kq	684	10	)	)	-RRB-
cord-010027-r0tl01kq	684	11	may	may	MD
cord-010027-r0tl01kq	684	12	play	play	VB
cord-010027-r0tl01kq	684	13	a	a	DT
cord-010027-r0tl01kq	684	14	role	role	NN
cord-010027-r0tl01kq	684	15	in	in	IN
cord-010027-r0tl01kq	684	16	this	this	DT
cord-010027-r0tl01kq	684	17	process	process	NN
cord-010027-r0tl01kq	684	18	.	.	.
cord-010027-r0tl01kq	685	1	We	-PRON-	PRP
cord-010027-r0tl01kq	685	2	have	have	VBP
cord-010027-r0tl01kq	685	3	investigated	investigate	VBN
cord-010027-r0tl01kq	685	4	the	the	DT
cord-010027-r0tl01kq	685	5	role	role	NN
cord-010027-r0tl01kq	685	6	of	of	IN
cord-010027-r0tl01kq	685	7	IGFBP	IGFBP	NNP
cord-010027-r0tl01kq	685	8	proteins	protein	NNS
cord-010027-r0tl01kq	685	9	in	in	IN
cord-010027-r0tl01kq	685	10	TR	TR	NNP
cord-010027-r0tl01kq	685	11	BC	BC	NNP
cord-010027-r0tl01kq	685	12	.	.	.
cord-010027-r0tl01kq	686	1	IGF	IGF	NNP
cord-010027-r0tl01kq	686	2	axis	axis	NN
cord-010027-r0tl01kq	686	3	genes	gene	NNS
cord-010027-r0tl01kq	686	4	were	be	VBD
cord-010027-r0tl01kq	686	5	evaluated	evaluate	VBN
cord-010027-r0tl01kq	686	6	in	in	IN
cord-010027-r0tl01kq	686	7	MCF-7	MCF-7	NNP
cord-010027-r0tl01kq	686	8	(	(	-LRB-
cord-010027-r0tl01kq	686	9	wt	wt	NN
cord-010027-r0tl01kq	686	10	)	)	-RRB-
cord-010027-r0tl01kq	686	11	cells	cell	NNS
cord-010027-r0tl01kq	686	12	and	and	CC
cord-010027-r0tl01kq	686	13	tamoxifen	tamoxifen	NN
cord-010027-r0tl01kq	686	14	-	-	HYPH
cord-010027-r0tl01kq	686	15	resistant	resistant	JJ
cord-010027-r0tl01kq	686	16	(	(	-LRB-
cord-010027-r0tl01kq	686	17	TamR	tamr	NN
cord-010027-r0tl01kq	686	18	)	)	-RRB-
cord-010027-r0tl01kq	686	19	variants	variant	NNS
cord-010027-r0tl01kq	686	20	using	use	VBG
cord-010027-r0tl01kq	686	21	qRT	qrt	ADD
cord-010027-r0tl01kq	686	22	-	-	HYPH
cord-010027-r0tl01kq	686	23	PCR	PCR	NNP
cord-010027-r0tl01kq	686	24	and	and	CC
cord-010027-r0tl01kq	686	25	confirmed	confirm	VBN
cord-010027-r0tl01kq	686	26	by	by	IN
cord-010027-r0tl01kq	686	27	ELISA	ELISA	NNP
cord-010027-r0tl01kq	686	28	,	,	,
cord-010027-r0tl01kq	686	29	Western	Western	NNP
cord-010027-r0tl01kq	686	30	,	,	,
cord-010027-r0tl01kq	686	31	and	and	CC
cord-010027-r0tl01kq	686	32	Ligand	Ligand	NNP
cord-010027-r0tl01kq	686	33	blotting	blotting	NN
cord-010027-r0tl01kq	686	34	.	.	.
cord-010027-r0tl01kq	687	1	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	687	2	&	&	CC
cord-010027-r0tl01kq	687	3	-5	-5	NNP
cord-010027-r0tl01kq	687	4	were	be	VBD
cord-010027-r0tl01kq	687	5	knocked	knock	VBN
cord-010027-r0tl01kq	687	6	down	down	RP
cord-010027-r0tl01kq	687	7	by	by	IN
cord-010027-r0tl01kq	687	8	shRNA	shrna	NN
cord-010027-r0tl01kq	687	9	transfection	transfection	NN
cord-010027-r0tl01kq	687	10	,	,	,
cord-010027-r0tl01kq	687	11	and	and	CC
cord-010027-r0tl01kq	687	12	subsequent	subsequent	JJ
cord-010027-r0tl01kq	687	13	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	687	14	to	to	IN
cord-010027-r0tl01kq	687	15	4-hydroxytamoxifen	4-hydroxytamoxifen	CD
cord-010027-r0tl01kq	687	16	(	(	-LRB-
cord-010027-r0tl01kq	687	17	4-HT	4-ht	CD
cord-010027-r0tl01kq	687	18	)	)	-RRB-
cord-010027-r0tl01kq	687	19	was	be	VBD
cord-010027-r0tl01kq	687	20	determined	determine	VBN
cord-010027-r0tl01kq	687	21	via	via	IN
cord-010027-r0tl01kq	687	22	WST-1	WST-1	NNP
cord-010027-r0tl01kq	687	23	.	.	.
cord-010027-r0tl01kq	688	1	Cell	cell	NN
cord-010027-r0tl01kq	688	2	migration	migration	NN
cord-010027-r0tl01kq	688	3	was	be	VBD
cord-010027-r0tl01kq	688	4	investigated	investigate	VBN
cord-010027-r0tl01kq	688	5	by	by	IN
cord-010027-r0tl01kq	688	6	using	use	VBG
cord-010027-r0tl01kq	688	7	the	the	DT
cord-010027-r0tl01kq	688	8	Incucyte	Incucyte	NNP
cord-010027-r0tl01kq	688	9	system	system	NN
cord-010027-r0tl01kq	688	10	.	.	.
cord-010027-r0tl01kq	689	1	IGFBP-2	igfbp-2	JJ
cord-010027-r0tl01kq	689	2	expression	expression	NN
cord-010027-r0tl01kq	689	3	was	be	VBD
cord-010027-r0tl01kq	689	4	evaluated	evaluate	VBN
cord-010027-r0tl01kq	689	5	in	in	IN
cord-010027-r0tl01kq	689	6	424	424	CD
cord-010027-r0tl01kq	689	7	BC	BC	NNP
cord-010027-r0tl01kq	689	8	cases	case	NNS
cord-010027-r0tl01kq	689	9	by	by	IN
cord-010027-r0tl01kq	689	10	TMA	TMA	NNP
cord-010027-r0tl01kq	689	11	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	689	12	.	.	.
cord-010027-r0tl01kq	690	1	Five	five	CD
cord-010027-r0tl01kq	690	2	out	out	IN
cord-010027-r0tl01kq	690	3	of	of	IN
cord-010027-r0tl01kq	690	4	10	10	CD
cord-010027-r0tl01kq	690	5	genes	gene	NNS
cord-010027-r0tl01kq	690	6	of	of	IN
cord-010027-r0tl01kq	690	7	the	the	DT
cord-010027-r0tl01kq	690	8	IGF	IGF	NNP
cord-010027-r0tl01kq	690	9	axis	axis	NN
cord-010027-r0tl01kq	690	10	(	(	-LRB-
cord-010027-r0tl01kq	690	11	IGF	IGF	NNP
cord-010027-r0tl01kq	690	12	-	-	HYPH
cord-010027-r0tl01kq	690	13	IR	IR	NNP
cord-010027-r0tl01kq	690	14	,	,	,
cord-010027-r0tl01kq	690	15	IGF-2R	IGF-2R	NNP
cord-010027-r0tl01kq	690	16	,	,	,
cord-010027-r0tl01kq	690	17	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	690	18	,	,	,
cord-010027-r0tl01kq	690	19	-4	-4	NNP
cord-010027-r0tl01kq	690	20	and	and	CC
cord-010027-r0tl01kq	690	21	-5	-5	NNP
cord-010027-r0tl01kq	690	22	)	)	-RRB-
cord-010027-r0tl01kq	690	23	had	have	VBD
cord-010027-r0tl01kq	690	24	the	the	DT
cord-010027-r0tl01kq	690	25	highest	high	JJS
cord-010027-r0tl01kq	690	26	expression	expression	NN
cord-010027-r0tl01kq	690	27	levels	level	NNS
cord-010027-r0tl01kq	690	28	by	by	IN
cord-010027-r0tl01kq	690	29	both	both	DT
cord-010027-r0tl01kq	690	30	parental	parental	JJ
cord-010027-r0tl01kq	690	31	wt	wt	NN
cord-010027-r0tl01kq	690	32	and	and	CC
cord-010027-r0tl01kq	690	33	TamR	TamR	NNP
cord-010027-r0tl01kq	690	34	cells	cell	NNS
cord-010027-r0tl01kq	690	35	.	.	.
cord-010027-r0tl01kq	691	1	IGFBP-5	IGFBP-5	NNP
cord-010027-r0tl01kq	691	2	was	be	VBD
cord-010027-r0tl01kq	691	3	down	down	RB
cord-010027-r0tl01kq	691	4	-	-	HYPH
cord-010027-r0tl01kq	691	5	regulated	regulate	VBN
cord-010027-r0tl01kq	691	6	by	by	IN
cord-010027-r0tl01kq	691	7	~7-fold	~7-fold	NNP
cord-010027-r0tl01kq	691	8	while	while	IN
cord-010027-r0tl01kq	691	9	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	691	10	was	be	VBD
cord-010027-r0tl01kq	691	11	up	up	RB
cord-010027-r0tl01kq	691	12	-	-	HYPH
cord-010027-r0tl01kq	691	13	regulated	regulate	VBN
cord-010027-r0tl01kq	691	14	by	by	IN
cord-010027-r0tl01kq	692	1	~2-fold	~2-fold	NNP
cord-010027-r0tl01kq	693	1	in	in	IN
cord-010027-r0tl01kq	693	2	TamR	TamR	NNP
cord-010027-r0tl01kq	693	3	versus	versus	IN
cord-010027-r0tl01kq	693	4	wt	wt	NN
cord-010027-r0tl01kq	693	5	cells	cell	NNS
cord-010027-r0tl01kq	693	6	(	(	-LRB-
cord-010027-r0tl01kq	693	7	mRNA	mrna	NN
cord-010027-r0tl01kq	693	8	and	and	CC
cord-010027-r0tl01kq	693	9	protein	protein	NN
cord-010027-r0tl01kq	693	10	levels	level	NNS
cord-010027-r0tl01kq	693	11	)	)	-RRB-
cord-010027-r0tl01kq	693	12	.	.	.
cord-010027-r0tl01kq	694	1	Significantly	significantly	RB
cord-010027-r0tl01kq	694	2	,	,	,
cord-010027-r0tl01kq	694	3	a	a	DT
cord-010027-r0tl01kq	694	4	knockdown	knockdown	NN
cord-010027-r0tl01kq	694	5	of	of	IN
cord-010027-r0tl01kq	694	6	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	694	7	in	in	IN
cord-010027-r0tl01kq	694	8	TamR	TamR	NNP
cord-010027-r0tl01kq	694	9	cells	cell	NNS
cord-010027-r0tl01kq	694	10	restored	restore	VBD
cord-010027-r0tl01kq	694	11	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	694	12	to	to	IN
cord-010027-r0tl01kq	694	13	(	(	-LRB-
cord-010027-r0tl01kq	694	14	4-HT	4-ht	CD
cord-010027-r0tl01kq	694	15	)	)	-RRB-
cord-010027-r0tl01kq	694	16	,	,	,
cord-010027-r0tl01kq	694	17	reduced	reduce	VBN
cord-010027-r0tl01kq	694	18	ERα	ERα	NNS
cord-010027-r0tl01kq	694	19	expression	expression	NN
cord-010027-r0tl01kq	694	20	to	to	IN
cord-010027-r0tl01kq	694	21	45	45	CD
cord-010027-r0tl01kq	694	22	±	±	CD
cord-010027-r0tl01kq	694	23	11.9	11.9	CD
cord-010027-r0tl01kq	694	24	%	%	NN
cord-010027-r0tl01kq	694	25	and	and	CC
cord-010027-r0tl01kq	694	26	enhanced	enhanced	JJ
cord-010027-r0tl01kq	694	27	cell	cell	NN
cord-010027-r0tl01kq	694	28	migration	migration	NN
cord-010027-r0tl01kq	694	29	.	.	.
cord-010027-r0tl01kq	695	1	Expression	expression	NN
cord-010027-r0tl01kq	695	2	of	of	IN
cord-010027-r0tl01kq	695	3	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	695	4	was	be	VBD
cord-010027-r0tl01kq	695	5	significantly	significantly	RB
cord-010027-r0tl01kq	695	6	(	(	-LRB-
cord-010027-r0tl01kq	695	7	P	p	NN
cord-010027-r0tl01kq	695	8	<	<	XX
cord-010027-r0tl01kq	695	9	0.001	0.001	CD
cord-010027-r0tl01kq	695	10	)	)	-RRB-
cord-010027-r0tl01kq	695	11	associated	associate	VBN
cord-010027-r0tl01kq	695	12	with	with	IN
cord-010027-r0tl01kq	695	13	survival	survival	NN
cord-010027-r0tl01kq	695	14	advantage	advantage	NN
cord-010027-r0tl01kq	695	15	in	in	IN
cord-010027-r0tl01kq	695	16	TR	tr	NN
cord-010027-r0tl01kq	695	17	patients	patient	NNS
cord-010027-r0tl01kq	695	18	.	.	.
cord-010027-r0tl01kq	696	1	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	696	2	and	and	CC
cord-010027-r0tl01kq	696	3	IGFPB-5	IGFPB-5	NNPS
cord-010027-r0tl01kq	696	4	are	be	VBP
cord-010027-r0tl01kq	696	5	reciprocally	reciprocally	RB
cord-010027-r0tl01kq	696	6	regulated	regulate	VBN
cord-010027-r0tl01kq	696	7	in	in	IN
cord-010027-r0tl01kq	696	8	the	the	DT
cord-010027-r0tl01kq	696	9	acquisition	acquisition	NN
cord-010027-r0tl01kq	696	10	of	of	IN
cord-010027-r0tl01kq	696	11	TR	TR	NNP
cord-010027-r0tl01kq	696	12	by	by	IN
cord-010027-r0tl01kq	696	13	MCF-7	MCF-7	NNP
cord-010027-r0tl01kq	696	14	cells	cell	NNS
cord-010027-r0tl01kq	696	15	.	.	.
cord-010027-r0tl01kq	697	1	IGFBP-2	IGFBP-2	NNP
cord-010027-r0tl01kq	697	2	may	may	MD
cord-010027-r0tl01kq	697	3	play	play	VB
cord-010027-r0tl01kq	697	4	a	a	DT
cord-010027-r0tl01kq	697	5	role	role	NN
cord-010027-r0tl01kq	697	6	in	in	IN
cord-010027-r0tl01kq	697	7	the	the	DT
cord-010027-r0tl01kq	697	8	development	development	NN
cord-010027-r0tl01kq	697	9	of	of	IN
cord-010027-r0tl01kq	697	10	TR	TR	NNP
cord-010027-r0tl01kq	697	11	in	in	IN
cord-010027-r0tl01kq	697	12	vitro	vitro	FW
cord-010027-r0tl01kq	697	13	and	and	CC
cord-010027-r0tl01kq	697	14	its	-PRON-	PRP$
cord-010027-r0tl01kq	697	15	high	high	JJ
cord-010027-r0tl01kq	697	16	levels	level	NNS
cord-010027-r0tl01kq	697	17	in	in	IN
cord-010027-r0tl01kq	697	18	clinical	clinical	JJ
cord-010027-r0tl01kq	697	19	samples	sample	NNS
cord-010027-r0tl01kq	697	20	may	may	MD
cord-010027-r0tl01kq	697	21	predict	predict	VB
cord-010027-r0tl01kq	697	22	TR	TR	NNP
cord-010027-r0tl01kq	697	23	.	.	.
cord-010027-r0tl01kq	698	1	Purpose	purpose	NN
cord-010027-r0tl01kq	698	2	of	of	IN
cord-010027-r0tl01kq	698	3	the	the	DT
cord-010027-r0tl01kq	698	4	Study	study	NN
cord-010027-r0tl01kq	698	5	:	:	:
cord-010027-r0tl01kq	698	6	Several	several	JJ
cord-010027-r0tl01kq	698	7	lines	line	NNS
cord-010027-r0tl01kq	698	8	of	of	IN
cord-010027-r0tl01kq	698	9	evidence	evidence	NN
cord-010027-r0tl01kq	698	10	are	be	VBP
cord-010027-r0tl01kq	698	11	currently	currently	RB
cord-010027-r0tl01kq	698	12	suggesting	suggest	VBG
cord-010027-r0tl01kq	698	13	that	that	IN
cord-010027-r0tl01kq	698	14	the	the	DT
cord-010027-r0tl01kq	698	15	morphologic	morphologic	JJ
cord-010027-r0tl01kq	698	16	heterogeneity	heterogeneity	NN
cord-010027-r0tl01kq	698	17	of	of	IN
cord-010027-r0tl01kq	698	18	breast	breast	NN
cord-010027-r0tl01kq	698	19	cancer	cancer	NN
cord-010027-r0tl01kq	698	20	is	be	VBZ
cord-010027-r0tl01kq	698	21	mirrored	mirror	VBN
cord-010027-r0tl01kq	698	22	at	at	IN
cord-010027-r0tl01kq	698	23	the	the	DT
cord-010027-r0tl01kq	698	24	genetic	genetic	JJ
cord-010027-r0tl01kq	698	25	level	level	NN
cord-010027-r0tl01kq	698	26	.	.	.
cord-010027-r0tl01kq	699	1	Understanding	understand	VBG
cord-010027-r0tl01kq	699	2	the	the	DT
cord-010027-r0tl01kq	699	3	molecular	molecular	JJ
cord-010027-r0tl01kq	699	4	genetic	genetic	JJ
cord-010027-r0tl01kq	699	5	evolution	evolution	NN
cord-010027-r0tl01kq	699	6	of	of	IN
cord-010027-r0tl01kq	699	7	BC	BC	NNP
cord-010027-r0tl01kq	699	8	would	would	MD
cord-010027-r0tl01kq	699	9	contribute	contribute	VB
cord-010027-r0tl01kq	699	10	further	further	JJ
cord-010027-r0tl01kq	699	11	insights	insight	NNS
cord-010027-r0tl01kq	699	12	into	into	IN
cord-010027-r0tl01kq	699	13	the	the	DT
cord-010027-r0tl01kq	699	14	molecular	molecular	JJ
cord-010027-r0tl01kq	699	15	derangements	derangement	NNS
cord-010027-r0tl01kq	699	16	driving	drive	VBG
cord-010027-r0tl01kq	699	17	disease	disease	NN
cord-010027-r0tl01kq	699	18	progression	progression	NN
cord-010027-r0tl01kq	699	19	.	.	.
cord-010027-r0tl01kq	700	1	Moreover	moreover	RB
cord-010027-r0tl01kq	700	2	,	,	,
cord-010027-r0tl01kq	700	3	varied	varied	JJ
cord-010027-r0tl01kq	700	4	clinical	clinical	JJ
cord-010027-r0tl01kq	700	5	outcome	outcome	NN
cord-010027-r0tl01kq	700	6	and	and	CC
cord-010027-r0tl01kq	700	7	response	response	NN
cord-010027-r0tl01kq	700	8	to	to	IN
cord-010027-r0tl01kq	700	9	similar	similar	JJ
cord-010027-r0tl01kq	700	10	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	700	11	regimen	regimen	NN
cord-010027-r0tl01kq	700	12	is	be	VBZ
cord-010027-r0tl01kq	700	13	attributed	attribute	VBN
cord-010027-r0tl01kq	700	14	,	,	,
cord-010027-r0tl01kq	700	15	at	at	IN
cord-010027-r0tl01kq	700	16	least	least	JJS
cord-010027-r0tl01kq	700	17	in	in	IN
cord-010027-r0tl01kq	700	18	-	-	HYPH
cord-010027-r0tl01kq	700	19	part	part	NN
cord-010027-r0tl01kq	700	20	to	to	IN
cord-010027-r0tl01kq	700	21	intratumoural	intratumoural	JJ
cord-010027-r0tl01kq	700	22	heterogeneity	heterogeneity	NN
cord-010027-r0tl01kq	700	23	.	.	.
cord-010027-r0tl01kq	701	1	NGS	NGS	NNP
cord-010027-r0tl01kq	701	2	can	can	MD
cord-010027-r0tl01kq	701	3	reliably	reliably	RB
cord-010027-r0tl01kq	701	4	study	study	VB
cord-010027-r0tl01kq	701	5	the	the	DT
cord-010027-r0tl01kq	701	6	genetic	genetic	JJ
cord-010027-r0tl01kq	701	7	events	event	NNS
cord-010027-r0tl01kq	701	8	using	use	VBG
cord-010027-r0tl01kq	701	9	miniscule	miniscule	JJ
cord-010027-r0tl01kq	701	10	amounts	amount	NNS
cord-010027-r0tl01kq	701	11	of	of	IN
cord-010027-r0tl01kq	701	12	genomic	genomic	JJ
cord-010027-r0tl01kq	701	13	DNA	dna	NN
cord-010027-r0tl01kq	701	14	.	.	.
cord-010027-r0tl01kq	702	1	Methods	method	NNS
cord-010027-r0tl01kq	702	2	:	:	:
cord-010027-r0tl01kq	703	1	gDNA	gDNA	NNP
cord-010027-r0tl01kq	703	2	was	be	VBD
cord-010027-r0tl01kq	703	3	extracted	extract	VBN
cord-010027-r0tl01kq	703	4	from	from	IN
cord-010027-r0tl01kq	703	5	FFPE	FFPE	NNP
cord-010027-r0tl01kq	703	6	tissue	tissue	NN
cord-010027-r0tl01kq	703	7	sections	section	NNS
cord-010027-r0tl01kq	703	8	from	from	IN
cord-010027-r0tl01kq	703	9	a	a	DT
cord-010027-r0tl01kq	703	10	case	case	NN
cord-010027-r0tl01kq	703	11	of	of	IN
cord-010027-r0tl01kq	703	12	invasive	invasive	JJ
cord-010027-r0tl01kq	703	13	duct	duct	NN
cord-010027-r0tl01kq	703	14	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	703	15	(	(	-LRB-
cord-010027-r0tl01kq	703	16	3	3	CD
cord-010027-r0tl01kq	703	17	primary	primary	JJ
cord-010027-r0tl01kq	703	18	tumour	tumour	NN
cord-010027-r0tl01kq	703	19	samples	sample	NNS
cord-010027-r0tl01kq	703	20	and	and	CC
cord-010027-r0tl01kq	703	21	3	3	CD
cord-010027-r0tl01kq	703	22	samples	sample	NNS
cord-010027-r0tl01kq	703	23	from	from	IN
cord-010027-r0tl01kq	703	24	positive	positive	JJ
cord-010027-r0tl01kq	703	25	axillary	axillary	JJ
cord-010027-r0tl01kq	703	26	lymph	lymph	NN
cord-010027-r0tl01kq	703	27	node	node	NN
cord-010027-r0tl01kq	703	28	metastases	metastasis	NNS
cord-010027-r0tl01kq	703	29	)	)	-RRB-
cord-010027-r0tl01kq	703	30	.	.	.
cord-010027-r0tl01kq	704	1	Sample	sample	NN
cord-010027-r0tl01kq	704	2	preparation	preparation	NN
cord-010027-r0tl01kq	704	3	and	and	CC
cord-010027-r0tl01kq	704	4	exome	exome	NN
cord-010027-r0tl01kq	704	5	enrichment	enrichment	NN
cord-010027-r0tl01kq	704	6	was	be	VBD
cord-010027-r0tl01kq	704	7	performed	perform	VBN
cord-010027-r0tl01kq	704	8	using	use	VBG
cord-010027-r0tl01kq	704	9	Nextera	Nextera	NNP
cord-010027-r0tl01kq	704	10	Rapid	Rapid	NNP
cord-010027-r0tl01kq	704	11	Capture	Capture	NNP
cord-010027-r0tl01kq	704	12	exome	exome	NN
cord-010027-r0tl01kq	704	13	kits	kit	NNS
cord-010027-r0tl01kq	704	14	(	(	-LRB-
cord-010027-r0tl01kq	704	15	illumina	illumina	NNP
cord-010027-r0tl01kq	704	16	,	,	,
cord-010027-r0tl01kq	704	17	FC-140	FC-140	NNP
cord-010027-r0tl01kq	704	18	-	-	HYPH
cord-010027-r0tl01kq	704	19	1000	1000	CD
cord-010027-r0tl01kq	704	20	)	)	-RRB-
cord-010027-r0tl01kq	704	21	.	.	.
cord-010027-r0tl01kq	705	1	Exome	Exome	NNP
cord-010027-r0tl01kq	705	2	sequencing	sequencing	NN
cord-010027-r0tl01kq	705	3	was	be	VBD
cord-010027-r0tl01kq	705	4	performed	perform	VBN
cord-010027-r0tl01kq	705	5	using	use	VBG
cord-010027-r0tl01kq	705	6	illumina	illumina	NNP
cord-010027-r0tl01kq	705	7	MiSeq	MiSeq	NNP
cord-010027-r0tl01kq	705	8	with	with	IN
cord-010027-r0tl01kq	705	9	15x	15x	CD
cord-010027-r0tl01kq	705	10	depth	depth	NN
cord-010027-r0tl01kq	705	11	of	of	IN
cord-010027-r0tl01kq	705	12	coverage	coverage	NN
cord-010027-r0tl01kq	705	13	(	(	-LRB-
cord-010027-r0tl01kq	705	14	following	follow	VBG
cord-010027-r0tl01kq	705	15	adapter	adapter	NN
cord-010027-r0tl01kq	705	16	/	/	SYM
cord-010027-r0tl01kq	705	17	barcode	barcode	NN
cord-010027-r0tl01kq	705	18	trimming	trimming	NN
cord-010027-r0tl01kq	705	19	)	)	-RRB-
cord-010027-r0tl01kq	705	20	.	.	.
cord-010027-r0tl01kq	706	1	Exploratory	exploratory	JJ
cord-010027-r0tl01kq	706	2	analyses	analysis	NNS
cord-010027-r0tl01kq	706	3	and	and	CC
cord-010027-r0tl01kq	706	4	data	datum	NNS
cord-010027-r0tl01kq	706	5	mining	mining	NN
cord-010027-r0tl01kq	706	6	were	be	VBD
cord-010027-r0tl01kq	706	7	executed	execute	VBN
cord-010027-r0tl01kq	706	8	regarding	regard	VBG
cord-010027-r0tl01kq	706	9	variant	variant	NN
cord-010027-r0tl01kq	706	10	(	(	-LRB-
cord-010027-r0tl01kq	706	11	s	s	NN
cord-010027-r0tl01kq	706	12	)	)	-RRB-
cord-010027-r0tl01kq	706	13	concordance/	concordance/	.
cord-010027-r0tl01kq	706	14	discordance	discordance	NN
cord-010027-r0tl01kq	706	15	between	between	IN
cord-010027-r0tl01kq	706	16	primary	primary	JJ
cord-010027-r0tl01kq	706	17	tumour	tumour	NN
cord-010027-r0tl01kq	706	18	samples	sample	NNS
cord-010027-r0tl01kq	706	19	and	and	CC
cord-010027-r0tl01kq	706	20	their	-PRON-	PRP$
cord-010027-r0tl01kq	706	21	respective	respective	JJ
cord-010027-r0tl01kq	706	22	metastatic	metastatic	JJ
cord-010027-r0tl01kq	706	23	variants	variant	NNS
cord-010027-r0tl01kq	706	24	.	.	.
cord-010027-r0tl01kq	707	1	Summary	summary	NN
cord-010027-r0tl01kq	707	2	of	of	IN
cord-010027-r0tl01kq	707	3	Results	result	NNS
cord-010027-r0tl01kq	707	4	:	:	:
cord-010027-r0tl01kq	708	1	Initial	initial	JJ
cord-010027-r0tl01kq	708	2	findings	finding	NNS
cord-010027-r0tl01kq	708	3	revealed	reveal	VBD
cord-010027-r0tl01kq	708	4	37	37	CD
cord-010027-r0tl01kq	708	5	candidate	candidate	NN
cord-010027-r0tl01kq	708	6	indels	indel	NNS
cord-010027-r0tl01kq	708	7	common	common	JJ
cord-010027-r0tl01kq	708	8	to	to	IN
cord-010027-r0tl01kq	708	9	all	all	DT
cord-010027-r0tl01kq	708	10	three	three	CD
cord-010027-r0tl01kq	708	11	axillary	axillary	JJ
cord-010027-r0tl01kq	708	12	lymph	lymph	NN
cord-010027-r0tl01kq	708	13	node	node	NN
cord-010027-r0tl01kq	708	14	samples	sample	NNS
cord-010027-r0tl01kq	708	15	yet	yet	RB
cord-010027-r0tl01kq	708	16	absent	absent	JJ
cord-010027-r0tl01kq	708	17	from	from	IN
cord-010027-r0tl01kq	708	18	the	the	DT
cord-010027-r0tl01kq	708	19	three	three	CD
cord-010027-r0tl01kq	708	20	primary	primary	JJ
cord-010027-r0tl01kq	708	21	tumour	tumour	NN
cord-010027-r0tl01kq	708	22	samples	sample	NNS
cord-010027-r0tl01kq	708	23	.	.	.
cord-010027-r0tl01kq	709	1	Several	several	JJ
cord-010027-r0tl01kq	709	2	genes	gene	NNS
cord-010027-r0tl01kq	709	3	have	have	VBP
cord-010027-r0tl01kq	709	4	been	be	VBN
cord-010027-r0tl01kq	709	5	identified	identify	VBN
cord-010027-r0tl01kq	709	6	as	as	IN
cord-010027-r0tl01kq	709	7	having	have	VBG
cord-010027-r0tl01kq	709	8	frameshift	frameshift	NN
cord-010027-r0tl01kq	709	9	mutations	mutation	NNS
cord-010027-r0tl01kq	709	10	caused	cause	VBN
cord-010027-r0tl01kq	709	11	by	by	IN
cord-010027-r0tl01kq	709	12	indels	indel	NNS
cord-010027-r0tl01kq	709	13	.	.	.
cord-010027-r0tl01kq	710	1	Molecular	molecular	JJ
cord-010027-r0tl01kq	710	2	players	player	NNS
cord-010027-r0tl01kq	710	3	previously	previously	RB
cord-010027-r0tl01kq	710	4	linked	link	VBN
cord-010027-r0tl01kq	710	5	to	to	IN
cord-010027-r0tl01kq	710	6	anti	anti	JJ
cord-010027-r0tl01kq	710	7	-	-	JJ
cord-010027-r0tl01kq	710	8	angiogenesis	angiogenesis	JJ
cord-010027-r0tl01kq	710	9	are	be	VBP
cord-010027-r0tl01kq	710	10	amongst	amongst	IN
cord-010027-r0tl01kq	710	11	the	the	DT
cord-010027-r0tl01kq	710	12	genes	gene	NNS
cord-010027-r0tl01kq	710	13	affected	affect	VBN
cord-010027-r0tl01kq	710	14	by	by	IN
cord-010027-r0tl01kq	710	15	indel	indel	NN
cord-010027-r0tl01kq	710	16	mutations	mutation	NNS
cord-010027-r0tl01kq	710	17	in	in	IN
cord-010027-r0tl01kq	710	18	their	-PRON-	PRP$
cord-010027-r0tl01kq	710	19	coding	coding	NN
cord-010027-r0tl01kq	710	20	sequences	sequence	NNS
cord-010027-r0tl01kq	710	21	that	that	WDT
cord-010027-r0tl01kq	710	22	may	may	MD
cord-010027-r0tl01kq	710	23	lead	lead	VB
cord-010027-r0tl01kq	710	24	to	to	IN
cord-010027-r0tl01kq	710	25	potential	potential	JJ
cord-010027-r0tl01kq	710	26	abrogation	abrogation	NN
cord-010027-r0tl01kq	710	27	of	of	IN
cord-010027-r0tl01kq	710	28	protein	protein	NN
cord-010027-r0tl01kq	710	29	function	function	NN
cord-010027-r0tl01kq	710	30	.	.	.
cord-010027-r0tl01kq	711	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	711	2	:	:	:
cord-010027-r0tl01kq	712	1	These	these	DT
cord-010027-r0tl01kq	712	2	initial	initial	JJ
cord-010027-r0tl01kq	712	3	findings	finding	NNS
cord-010027-r0tl01kq	712	4	provide	provide	VBP
cord-010027-r0tl01kq	712	5	the	the	DT
cord-010027-r0tl01kq	712	6	framework	framework	NN
cord-010027-r0tl01kq	712	7	for	for	IN
cord-010027-r0tl01kq	712	8	detailed	detailed	JJ
cord-010027-r0tl01kq	712	9	molecular	molecular	JJ
cord-010027-r0tl01kq	712	10	analyses	analysis	NNS
cord-010027-r0tl01kq	712	11	for	for	IN
cord-010027-r0tl01kq	712	12	assessing	assess	VBG
cord-010027-r0tl01kq	712	13	molecular	molecular	JJ
cord-010027-r0tl01kq	712	14	evolutionary	evolutionary	JJ
cord-010027-r0tl01kq	712	15	events	event	NNS
cord-010027-r0tl01kq	712	16	in	in	IN
cord-010027-r0tl01kq	712	17	primary	primary	JJ
cord-010027-r0tl01kq	712	18	breast	breast	NN
cord-010027-r0tl01kq	712	19	cancer	cancer	NN
cord-010027-r0tl01kq	712	20	and	and	CC
cord-010027-r0tl01kq	712	21	their	-PRON-	PRP$
cord-010027-r0tl01kq	712	22	corresponding	corresponding	JJ
cord-010027-r0tl01kq	712	23	metastases	metastasis	NNS
cord-010027-r0tl01kq	712	24	.	.	.
cord-010027-r0tl01kq	713	1	C	C	NNP
cord-010027-r0tl01kq	713	2	-	-	HYPH
cord-010027-r0tl01kq	713	3	MYC	MYC	NNP
cord-010027-r0tl01kq	713	4	is	be	VBZ
cord-010027-r0tl01kq	713	5	amplified	amplify	VBN
cord-010027-r0tl01kq	713	6	in	in	IN
cord-010027-r0tl01kq	713	7	approximately	approximately	RB
cord-010027-r0tl01kq	713	8	15	15	CD
cord-010027-r0tl01kq	713	9	%	%	NN
cord-010027-r0tl01kq	713	10	of	of	IN
cord-010027-r0tl01kq	713	11	breast	breast	NN
cord-010027-r0tl01kq	713	12	cancers	cancer	NNS
cord-010027-r0tl01kq	713	13	(	(	-LRB-
cord-010027-r0tl01kq	713	14	BC	BC	NNP
cord-010027-r0tl01kq	713	15	)	)	-RRB-
cord-010027-r0tl01kq	713	16	and	and	CC
cord-010027-r0tl01kq	713	17	is	be	VBZ
cord-010027-r0tl01kq	713	18	associated	associate	VBN
cord-010027-r0tl01kq	713	19	with	with	IN
cord-010027-r0tl01kq	713	20	poor	poor	JJ
cord-010027-r0tl01kq	713	21	outcome	outcome	NN
cord-010027-r0tl01kq	713	22	.	.	.
cord-010027-r0tl01kq	714	1	c	c	LS
cord-010027-r0tl01kq	714	2	-	-	HYPH
cord-010027-r0tl01kq	714	3	Myc	Myc	NNP
cord-010027-r0tl01kq	714	4	protein	protein	NN
cord-010027-r0tl01kq	714	5	is	be	VBZ
cord-010027-r0tl01kq	714	6	multi	multi	JJ
cord-010027-r0tl01kq	714	7	-	-	JJ
cord-010027-r0tl01kq	714	8	faceted	faceted	JJ
cord-010027-r0tl01kq	714	9	and	and	CC
cord-010027-r0tl01kq	714	10	participates	participate	VBZ
cord-010027-r0tl01kq	714	11	in	in	IN
cord-010027-r0tl01kq	714	12	many	many	JJ
cord-010027-r0tl01kq	714	13	aspects	aspect	NNS
cord-010027-r0tl01kq	714	14	of	of	IN
cord-010027-r0tl01kq	714	15	cellular	cellular	JJ
cord-010027-r0tl01kq	714	16	function	function	NN
cord-010027-r0tl01kq	714	17	and	and	CC
cord-010027-r0tl01kq	714	18	is	be	VBZ
cord-010027-r0tl01kq	714	19	linked	link	VBN
cord-010027-r0tl01kq	714	20	with	with	IN
cord-010027-r0tl01kq	714	21	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	714	22	response	response	NN
cord-010027-r0tl01kq	714	23	in	in	IN
cord-010027-r0tl01kq	714	24	BC	BC	NNP
cord-010027-r0tl01kq	714	25	.	.	.
cord-010027-r0tl01kq	715	1	We	-PRON-	PRP
cord-010027-r0tl01kq	715	2	hypothesised	hypothesise	VBD
cord-010027-r0tl01kq	715	3	that	that	IN
cord-010027-r0tl01kq	715	4	the	the	DT
cord-010027-r0tl01kq	715	5	functional	functional	JJ
cord-010027-r0tl01kq	715	6	role	role	NN
cord-010027-r0tl01kq	715	7	of	of	IN
cord-010027-r0tl01kq	715	8	c	c	NNP
cord-010027-r0tl01kq	715	9	-	-	HYPH
cord-010027-r0tl01kq	715	10	Myc	Myc	NNP
cord-010027-r0tl01kq	715	11	differs	differ	VBZ
cord-010027-r0tl01kq	715	12	between	between	IN
cord-010027-r0tl01kq	715	13	molecular	molecular	JJ
cord-010027-r0tl01kq	715	14	subtypes	subtype	NNS
cord-010027-r0tl01kq	715	15	of	of	IN
cord-010027-r0tl01kq	715	16	BC	BC	NNP
cord-010027-r0tl01kq	715	17	.	.	.
cord-010027-r0tl01kq	716	1	We	-PRON-	PRP
cord-010027-r0tl01kq	716	2	therefore	therefore	RB
cord-010027-r0tl01kq	716	3	investigated	investigate	VBD
cord-010027-r0tl01kq	716	4	the	the	DT
cord-010027-r0tl01kq	716	5	correlation	correlation	NN
cord-010027-r0tl01kq	716	6	between	between	IN
cord-010027-r0tl01kq	716	7	c	c	NNP
cord-010027-r0tl01kq	716	8	-	-	HYPH
cord-010027-r0tl01kq	716	9	Myc	Myc	NNP
cord-010027-r0tl01kq	716	10	protein	protein	NN
cord-010027-r0tl01kq	716	11	expression	expression	NN
cord-010027-r0tl01kq	716	12	and	and	CC
cord-010027-r0tl01kq	716	13	other	other	JJ
cord-010027-r0tl01kq	716	14	proteins	protein	NNS
cord-010027-r0tl01kq	716	15	involved	involve	VBN
cord-010027-r0tl01kq	716	16	in	in	IN
cord-010027-r0tl01kq	716	17	cell	cell	NN
cord-010027-r0tl01kq	716	18	cycle	cycle	NN
cord-010027-r0tl01kq	716	19	control	control	NN
cord-010027-r0tl01kq	716	20	,	,	,
cord-010027-r0tl01kq	716	21	proliferation	proliferation	NN
cord-010027-r0tl01kq	716	22	,	,	,
cord-010027-r0tl01kq	716	23	apoptosis	apoptosis	NN
cord-010027-r0tl01kq	716	24	and	and	CC
cord-010027-r0tl01kq	716	25	DNA	dna	NN
cord-010027-r0tl01kq	716	26	damage	damage	NN
cord-010027-r0tl01kq	716	27	together	together	RB
cord-010027-r0tl01kq	716	28	with	with	IN
cord-010027-r0tl01kq	716	29	clinicopathological	clinicopathological	JJ
cord-010027-r0tl01kq	716	30	parameters	parameter	NNS
cord-010027-r0tl01kq	716	31	,	,	,
cord-010027-r0tl01kq	716	32	outcome	outcome	NN
cord-010027-r0tl01kq	716	33	and	and	CC
cord-010027-r0tl01kq	716	34	treatments	treatment	NNS
cord-010027-r0tl01kq	716	35	in	in	IN
cord-010027-r0tl01kq	716	36	early	early	JJ
cord-010027-r0tl01kq	716	37	invasive	invasive	JJ
cord-010027-r0tl01kq	716	38	primary	primary	JJ
cord-010027-r0tl01kq	716	39	BC	BC	NNP
cord-010027-r0tl01kq	716	40	(	(	-LRB-
cord-010027-r0tl01kq	716	41	n=1,106	n=1,106	NNP
cord-010027-r0tl01kq	716	42	)	)	-RRB-
cord-010027-r0tl01kq	716	43	using	use	VBG
cord-010027-r0tl01kq	716	44	immunuohistochemistry	immunuohistochemistry	NNP
cord-010027-r0tl01kq	716	45	.	.	.
cord-010027-r0tl01kq	717	1	The	the	DT
cord-010027-r0tl01kq	717	2	METABRIC	METABRIC	NNP
cord-010027-r0tl01kq	717	3	BC	BC	NNP
cord-010027-r0tl01kq	717	4	cohort	cohort	NN
cord-010027-r0tl01kq	717	5	(	(	-LRB-
cord-010027-r0tl01kq	717	6	n=1,980	n=1,980	NNP
cord-010027-r0tl01kq	717	7	)	)	-RRB-
cord-010027-r0tl01kq	717	8	was	be	VBD
cord-010027-r0tl01kq	717	9	evaluated	evaluate	VBN
cord-010027-r0tl01kq	717	10	for	for	IN
cord-010027-r0tl01kq	717	11	c	c	NNP
cord-010027-r0tl01kq	717	12	-	-	HYPH
cord-010027-r0tl01kq	717	13	Myc	Myc	NNP
cord-010027-r0tl01kq	717	14	mRNA	mrna	NN
cord-010027-r0tl01kq	717	15	expression	expression	NN
cord-010027-r0tl01kq	717	16	.	.	.
cord-010027-r0tl01kq	718	1	In	in	IN
cord-010027-r0tl01kq	718	2	whole	whole	JJ
cord-010027-r0tl01kq	718	3	series	series	NN
cord-010027-r0tl01kq	718	4	,	,	,
cord-010027-r0tl01kq	718	5	there	there	EX
cord-010027-r0tl01kq	718	6	was	be	VBD
cord-010027-r0tl01kq	718	7	significant	significant	JJ
cord-010027-r0tl01kq	718	8	association	association	NN
cord-010027-r0tl01kq	718	9	between	between	IN
cord-010027-r0tl01kq	718	10	c	c	NNP
cord-010027-r0tl01kq	718	11	-	-	HYPH
cord-010027-r0tl01kq	718	12	Myc	Myc	NNP
cord-010027-r0tl01kq	718	13	protein	protein	NN
cord-010027-r0tl01kq	718	14	expression	expression	NN
cord-010027-r0tl01kq	718	15	with	with	IN
cord-010027-r0tl01kq	718	16	higher	high	JJR
cord-010027-r0tl01kq	718	17	tumour	tumour	NN
cord-010027-r0tl01kq	718	18	grade	grade	NN
cord-010027-r0tl01kq	718	19	,	,	,
cord-010027-r0tl01kq	718	20	lymph	lymph	NN
cord-010027-r0tl01kq	718	21	node(LN	node(ln	NN
cord-010027-r0tl01kq	718	22	)	)	-RRB-
cord-010027-r0tl01kq	718	23	positivity	positivity	NN
cord-010027-r0tl01kq	718	24	and	and	CC
cord-010027-r0tl01kq	718	25	medullary	medullary	NN
cord-010027-r0tl01kq	718	26	-	-	HYPH
cord-010027-r0tl01kq	718	27	like	like	JJ
cord-010027-r0tl01kq	718	28	tumours	tumour	NNS
cord-010027-r0tl01kq	718	29	.	.	.
cord-010027-r0tl01kq	719	1	C	C	NNP
cord-010027-r0tl01kq	719	2	-	-	HYPH
cord-010027-r0tl01kq	719	3	myc	myc	NNP
cord-010027-r0tl01kq	719	4	showed	show	VBD
cord-010027-r0tl01kq	719	5	differential	differential	NNP
cord-010027-r0tl01kq	719	6	association	association	NN
cord-010027-r0tl01kq	719	7	with	with	IN
cord-010027-r0tl01kq	719	8	other	other	JJ
cord-010027-r0tl01kq	719	9	proteins	protein	NNS
cord-010027-r0tl01kq	719	10	in	in	IN
cord-010027-r0tl01kq	719	11	the	the	DT
cord-010027-r0tl01kq	719	12	molecular	molecular	JJ
cord-010027-r0tl01kq	719	13	classes	class	NNS
cord-010027-r0tl01kq	719	14	.	.	.
cord-010027-r0tl01kq	720	1	In	in	IN
cord-010027-r0tl01kq	720	2	luminal	luminal	JJ
cord-010027-r0tl01kq	720	3	A	a	DT
cord-010027-r0tl01kq	720	4	tumours	tumour	NNS
cord-010027-r0tl01kq	720	5	,	,	,
cord-010027-r0tl01kq	720	6	c	c	NN
cord-010027-r0tl01kq	720	7	-	-	:
cord-010027-r0tl01kq	720	8	Myc	Myc	NNP
cord-010027-r0tl01kq	720	9	was	be	VBD
cord-010027-r0tl01kq	720	10	associated	associate	VBN
cord-010027-r0tl01kq	720	11	with	with	IN
cord-010027-r0tl01kq	720	12	ATM	ATM	NNS
cord-010027-r0tl01kq	720	13	(	(	-LRB-
cord-010027-r0tl01kq	720	14	p=0.005	p=0.005	NNP
cord-010027-r0tl01kq	720	15	)	)	-RRB-
cord-010027-r0tl01kq	721	1	,	,	,
cord-010027-r0tl01kq	721	2	Cyclin	Cyclin	NNP
cord-010027-r0tl01kq	721	3	B1	b1	NN
cord-010027-r0tl01kq	721	4	(	(	-LRB-
cord-010027-r0tl01kq	721	5	p=0.002	p=0.002	NNP
cord-010027-r0tl01kq	721	6	)	)	-RRB-
cord-010027-r0tl01kq	721	7	,	,	,
cord-010027-r0tl01kq	721	8	PIK3CA	pik3ca	NN
cord-010027-r0tl01kq	721	9	(	(	-LRB-
cord-010027-r0tl01kq	721	10	p=0.009	p=0.009	NN
cord-010027-r0tl01kq	721	11	)	)	-RRB-
cord-010027-r0tl01kq	721	12	and	and	CC
cord-010027-r0tl01kq	722	1	Ki67	Ki67	NNP
cord-010027-r0tl01kq	722	2	(	(	-LRB-
cord-010027-r0tl01kq	722	3	p<0.001	p<0.001	JJ
cord-010027-r0tl01kq	722	4	)	)	-RRB-
cord-010027-r0tl01kq	722	5	.	.	.
cord-010027-r0tl01kq	723	1	In	in	IN
cord-010027-r0tl01kq	723	2	contrast	contrast	NN
cord-010027-r0tl01kq	723	3	,	,	,
cord-010027-r0tl01kq	723	4	in	in	IN
cord-010027-r0tl01kq	723	5	basal	basal	NN
cord-010027-r0tl01kq	723	6	-	-	HYPH
cord-010027-r0tl01kq	723	7	like	like	JJ
cord-010027-r0tl01kq	723	8	tumours	tumour	NNS
cord-010027-r0tl01kq	723	9	,	,	,
cord-010027-r0tl01kq	723	10	c	c	NNP
cord-010027-r0tl01kq	723	11	-	-	:
cord-010027-r0tl01kq	723	12	Myc	Myc	NNP
cord-010027-r0tl01kq	723	13	showed	show	VBD
cord-010027-r0tl01kq	723	14	positive	positive	JJ
cord-010027-r0tl01kq	723	15	associated	associate	VBN
cord-010027-r0tl01kq	723	16	with	with	IN
cord-010027-r0tl01kq	723	17	Cyclin	Cyclin	NNP
cord-010027-r0tl01kq	723	18	E	E	NNP
cord-010027-r0tl01kq	723	19	(	(	-LRB-
cord-010027-r0tl01kq	723	20	p=0.003	p=0.003	NNP
cord-010027-r0tl01kq	723	21	)	)	-RRB-
cord-010027-r0tl01kq	723	22	and	and	CC
cord-010027-r0tl01kq	723	23	p16	p16	NN
cord-010027-r0tl01kq	723	24	(	(	-LRB-
cord-010027-r0tl01kq	723	25	p=0.042	p=0.042	NNP
cord-010027-r0tl01kq	723	26	)	)	-RRB-
cord-010027-r0tl01kq	723	27	expression	expression	NN
cord-010027-r0tl01kq	723	28	.	.	.
cord-010027-r0tl01kq	724	1	c	c	LS
cord-010027-r0tl01kq	724	2	-	-	:
cord-010027-r0tl01kq	724	3	Myc	Myc	NNP
cord-010027-r0tl01kq	724	4	was	be	VBD
cord-010027-r0tl01kq	724	5	an	an	DT
cord-010027-r0tl01kq	724	6	independent	independent	JJ
cord-010027-r0tl01kq	724	7	predictor	predictor	NN
cord-010027-r0tl01kq	724	8	of	of	IN
cord-010027-r0tl01kq	724	9	a	a	DT
cord-010027-r0tl01kq	724	10	shorter	shorter	RBR
cord-010027-r0tl01kq	724	11	distant	distant	JJ
cord-010027-r0tl01kq	724	12	metastases	metastasis	NNS
cord-010027-r0tl01kq	724	13	free	free	JJ
cord-010027-r0tl01kq	724	14	survival	survival	NN
cord-010027-r0tl01kq	724	15	in	in	IN
cord-010027-r0tl01kq	724	16	luminal	luminal	NN
cord-010027-r0tl01kq	725	1	A	a	DT
cord-010027-r0tl01kq	725	2	LN+	LN+	NNP
cord-010027-r0tl01kq	725	3	tumours	tumour	NNS
cord-010027-r0tl01kq	725	4	treated	treat	VBN
cord-010027-r0tl01kq	725	5	with	with	IN
cord-010027-r0tl01kq	725	6	endocrine	endocrine	JJ
cord-010027-r0tl01kq	725	7	therapy	therapy	NN
cord-010027-r0tl01kq	725	8	(	(	-LRB-
cord-010027-r0tl01kq	725	9	ET	et	NN
cord-010027-r0tl01kq	725	10	;	;	:
cord-010027-r0tl01kq	725	11	p=0.013	p=0.013	NNP
cord-010027-r0tl01kq	725	12	)	)	-RRB-
cord-010027-r0tl01kq	725	13	.	.	.
cord-010027-r0tl01kq	726	1	c	c	LS
cord-010027-r0tl01kq	726	2	-	-	HYPH
cord-010027-r0tl01kq	726	3	Myc	Myc	NNP
cord-010027-r0tl01kq	726	4	expression	expression	NN
cord-010027-r0tl01kq	726	5	did	do	VBD
cord-010027-r0tl01kq	726	6	not	not	RB
cord-010027-r0tl01kq	726	7	predict	predict	VB
cord-010027-r0tl01kq	726	8	patient	patient	JJ
cord-010027-r0tl01kq	726	9	outcome	outcome	NN
cord-010027-r0tl01kq	726	10	in	in	IN
cord-010027-r0tl01kq	726	11	the	the	DT
cord-010027-r0tl01kq	726	12	other	other	JJ
cord-010027-r0tl01kq	726	13	molecular	molecular	JJ
cord-010027-r0tl01kq	726	14	subtypes	subtype	NNS
cord-010027-r0tl01kq	726	15	with	with	IN
cord-010027-r0tl01kq	726	16	respect	respect	NN
cord-010027-r0tl01kq	726	17	to	to	IN
cord-010027-r0tl01kq	726	18	adjuvant	adjuvant	JJ
cord-010027-r0tl01kq	726	19	treatment	treatment	NN
cord-010027-r0tl01kq	726	20	.	.	.
cord-010027-r0tl01kq	727	1	High	high	JJ
cord-010027-r0tl01kq	727	2	c	c	NN
cord-010027-r0tl01kq	727	3	-	-	HYPH
cord-010027-r0tl01kq	727	4	Myc	Myc	NNP
cord-010027-r0tl01kq	727	5	mRNA	mrna	NN
cord-010027-r0tl01kq	727	6	expression	expression	NN
cord-010027-r0tl01kq	727	7	was	be	VBD
cord-010027-r0tl01kq	727	8	associated	associate	VBN
cord-010027-r0tl01kq	727	9	with	with	IN
cord-010027-r0tl01kq	727	10	higher	high	JJR
cord-010027-r0tl01kq	727	11	grade	grade	NN
cord-010027-r0tl01kq	727	12	and	and	CC
cord-010027-r0tl01kq	727	13	basal	basal	NN
cord-010027-r0tl01kq	727	14	phenotype	phenotype	NN
cord-010027-r0tl01kq	727	15	(	(	-LRB-
cord-010027-r0tl01kq	727	16	p<0.001	p<0.001	CD
cord-010027-r0tl01kq	727	17	)	)	-RRB-
cord-010027-r0tl01kq	727	18	.	.	.
cord-010027-r0tl01kq	728	1	In	in	IN
cord-010027-r0tl01kq	728	2	luminal	luminal	JJ
cord-010027-r0tl01kq	728	3	tumours	tumour	NNS
cord-010027-r0tl01kq	728	4	treated	treat	VBN
cord-010027-r0tl01kq	728	5	with	with	IN
cord-010027-r0tl01kq	728	6	ET	ET	NNP
cord-010027-r0tl01kq	728	7	,	,	,
cord-010027-r0tl01kq	728	8	c	c	NNP
cord-010027-r0tl01kq	728	9	-	-	HYPH
cord-010027-r0tl01kq	728	10	Myc	Myc	NNP
cord-010027-r0tl01kq	728	11	mRNA	mRNA	NNP
cord-010027-r0tl01kq	728	12	expression	expression	NN
cord-010027-r0tl01kq	728	13	was	be	VBD
cord-010027-r0tl01kq	728	14	associated	associate	VBN
cord-010027-r0tl01kq	728	15	with	with	IN
cord-010027-r0tl01kq	728	16	BC	BC	NNP
cord-010027-r0tl01kq	728	17	specific	specific	JJ
cord-010027-r0tl01kq	728	18	survival	survival	NN
cord-010027-r0tl01kq	728	19	(	(	-LRB-
cord-010027-r0tl01kq	728	20	p=0.001	p=0.001	NNP
cord-010027-r0tl01kq	728	21	)	)	-RRB-
cord-010027-r0tl01kq	728	22	.	.	.
cord-010027-r0tl01kq	729	1	c	c	LS
cord-010027-r0tl01kq	729	2	-	-	:
cord-010027-r0tl01kq	729	3	Myc	Myc	NNP
cord-010027-r0tl01kq	729	4	function	function	NN
cord-010027-r0tl01kq	729	5	is	be	VBZ
cord-010027-r0tl01kq	729	6	associated	associate	VBN
cord-010027-r0tl01kq	729	7	with	with	IN
cord-010027-r0tl01kq	729	8	specific	specific	JJ
cord-010027-r0tl01kq	729	9	molecular	molecular	JJ
cord-010027-r0tl01kq	729	10	subtypes	subtype	NNS
cord-010027-r0tl01kq	729	11	of	of	IN
cord-010027-r0tl01kq	729	12	BC	BC	NNP
cord-010027-r0tl01kq	729	13	and	and	CC
cord-010027-r0tl01kq	729	14	confers	confer	VBZ
cord-010027-r0tl01kq	729	15	resistance	resistance	NN
cord-010027-r0tl01kq	729	16	to	to	IN
cord-010027-r0tl01kq	729	17	ET	ET	NNP
cord-010027-r0tl01kq	729	18	.	.	.
cord-010027-r0tl01kq	730	1	The	the	DT
cord-010027-r0tl01kq	730	2	diverse	diverse	JJ
cord-010027-r0tl01kq	730	3	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	730	4	of	of	IN
cord-010027-r0tl01kq	730	5	c	c	NN
cord-010027-r0tl01kq	730	6	-	-	HYPH
cord-010027-r0tl01kq	730	7	Myc	Myc	NNP
cord-010027-r0tl01kq	730	8	function	function	NN
cord-010027-r0tl01kq	730	9	,	,	,
cord-010027-r0tl01kq	730	10	particularly	particularly	RB
cord-010027-r0tl01kq	730	11	in	in	IN
cord-010027-r0tl01kq	730	12	luminal	luminal	JJ
cord-010027-r0tl01kq	730	13	A	a	DT
cord-010027-r0tl01kq	730	14	BC	BC	NNP
cord-010027-r0tl01kq	730	15	,	,	,
cord-010027-r0tl01kq	730	16	warrants	warrant	NNS
cord-010027-r0tl01kq	730	17	further	further	JJ
cord-010027-r0tl01kq	730	18	investigation	investigation	NN
cord-010027-r0tl01kq	730	19	.	.	.
cord-010027-r0tl01kq	731	1	Metasin	Metasin	NNP
cord-010027-r0tl01kq	731	2	Axillary	Axillary	NNP
cord-010027-r0tl01kq	731	3	Predictive	Predictive	NNP
cord-010027-r0tl01kq	731	4	Score	Score	NNP
cord-010027-r0tl01kq	731	5	(	(	-LRB-
cord-010027-r0tl01kq	731	6	MAPS	map	NNS
cord-010027-r0tl01kq	731	7	)	)	-RRB-
cord-010027-r0tl01kq	731	8	:	:	:
cord-010027-r0tl01kq	731	9	A	a	DT
cord-010027-r0tl01kq	731	10	Measure	measure	NN
cord-010027-r0tl01kq	731	11	of	of	IN
cord-010027-r0tl01kq	731	12	Axillary	Axillary	NNP
cord-010027-r0tl01kq	731	13	Nodal	Nodal	NNP
cord-010027-r0tl01kq	731	14	Disease	Disease	NNP
cord-010027-r0tl01kq	731	15	Prediction	Prediction	NNP
cord-010027-r0tl01kq	731	16	to	to	TO
cord-010027-r0tl01kq	731	17	Provide	provide	VB
cord-010027-r0tl01kq	731	18	an	an	DT
cord-010027-r0tl01kq	731	19	Informed	Informed	NNP
cord-010027-r0tl01kq	731	20	Choice	Choice	NNP
cord-010027-r0tl01kq	731	21	for	for	IN
cord-010027-r0tl01kq	731	22	Breast	Breast	NNP
cord-010027-r0tl01kq	731	23	Cancer	Cancer	NNP
cord-010027-r0tl01kq	731	24	Patients	Patients	NNPS
cord-010027-r0tl01kq	731	25	and	and	CC
cord-010027-r0tl01kq	731	26	Surgeons	Surgeons	NNPS
cord-010027-r0tl01kq	731	27	P	P	NNP
cord-010027-r0tl01kq	731	28	PP	PP	NNP
cord-010027-r0tl01kq	731	29	Gopinath	Gopinath	NNP
cord-010027-r0tl01kq	731	30	1	1	CD
cord-010027-r0tl01kq	731	31	;	;	:
cord-010027-r0tl01kq	731	32	D	D	NNP
cord-010027-r0tl01kq	731	33	George	George	NNP
cord-010027-r0tl01kq	731	34	1	1	CD
cord-010027-r0tl01kq	731	35	;	;	:
cord-010027-r0tl01kq	731	36	P	P	NNP
cord-010027-r0tl01kq	731	37	Sai	Sai	NNP
cord-010027-r0tl01kq	731	38	-	-	HYPH
cord-010027-r0tl01kq	731	39	Giridhar	Giridhar	NNP
cord-010027-r0tl01kq	731	40	2	2	CD
cord-010027-r0tl01kq	731	41	;	;	:
cord-010027-r0tl01kq	731	42	S	S	NNP
cord-010027-r0tl01kq	731	43	Jader	Jader	NNP
cord-010027-r0tl01kq	731	44	1	1	CD
cord-010027-r0tl01kq	731	45	;	;	:
cord-010027-r0tl01kq	731	46	E	E	NNP
cord-010027-r0tl01kq	731	47	Arkoumani	Arkoumani	NNP
cord-010027-r0tl01kq	731	48	1	1	CD
cord-010027-r0tl01kq	731	49	;	;	:
cord-010027-r0tl01kq	731	50	S	S	NNP
cord-010027-r0tl01kq	731	51	Holt	Holt	NNP
cord-010027-r0tl01kq	731	52	2	2	CD
cord-010027-r0tl01kq	731	53	;	;	:
cord-010027-r0tl01kq	731	54	G	G	NNP
cord-010027-r0tl01kq	731	55	Francis	Francis	NNP
cord-010027-r0tl01kq	731	56	3	3	CD
cord-010027-r0tl01kq	731	57	;	;	:
cord-010027-r0tl01kq	731	58	C	C	NNP
cord-010027-r0tl01kq	731	59	Yiangou	Yiangou	NNP
cord-010027-r0tl01kq	731	60	3	3	CD
cord-010027-r0tl01kq	731	61	;	;	:
cord-010027-r0tl01kq	731	62	S	S	NNP
cord-010027-r0tl01kq	731	63	Al	Al	NNP
cord-010027-r0tl01kq	731	64	Ramadhani	Ramadhani	NNP
cord-010027-r0tl01kq	731	65	4	4	CD
cord-010027-r0tl01kq	731	66	;	;	:
cord-010027-r0tl01kq	731	67	S	S	NNP
cord-010027-r0tl01kq	731	68	El	El	NNP
cord-010027-r0tl01kq	731	69	Sheikh	Sheikh	NNP
cord-010027-r0tl01kq	731	70	5	5	CD
cord-010027-r0tl01kq	731	71	;	;	:
cord-010027-r0tl01kq	731	72	N	n	CD
cord-010027-r0tl01kq	731	73	Agrawal	Agrawal	NNP
cord-010027-r0tl01kq	731	74	3	3	CD
cord-010027-r0tl01kq	731	75	;	;	:
cord-010027-r0tl01kq	732	1	V	V	NNP
cord-010027-r0tl01kq	732	2	Sundaresan	Sundaresan	NNP
cord-010027-r0tl01kq	732	3	1	1	CD
cord-010027-r0tl01kq	732	4	Purpose	Purpose	NNP
cord-010027-r0tl01kq	732	5	of	of	IN
cord-010027-r0tl01kq	732	6	study	study	NN
cord-010027-r0tl01kq	732	7	:	:	:
cord-010027-r0tl01kq	732	8	Intra	intra	JJ
cord-010027-r0tl01kq	732	9	-	-	JJ
cord-010027-r0tl01kq	732	10	operative	operative	JJ
cord-010027-r0tl01kq	732	11	sentinel	sentinel	JJ
cord-010027-r0tl01kq	732	12	lymph	lymph	NN
cord-010027-r0tl01kq	732	13	node	node	NN
cord-010027-r0tl01kq	732	14	sampling	sampling	NN
cord-010027-r0tl01kq	732	15	and	and	CC
cord-010027-r0tl01kq	732	16	molecular	molecular	JJ
cord-010027-r0tl01kq	732	17	analysis	analysis	NN
cord-010027-r0tl01kq	732	18	empowers	empower	VBZ
cord-010027-r0tl01kq	732	19	the	the	DT
cord-010027-r0tl01kq	732	20	surgeon	surgeon	NN
cord-010027-r0tl01kq	732	21	to	to	TO
cord-010027-r0tl01kq	732	22	carry	carry	VB
cord-010027-r0tl01kq	732	23	out	out	RP
cord-010027-r0tl01kq	732	24	axillary	axillary	JJ
cord-010027-r0tl01kq	732	25	clearance	clearance	NN
cord-010027-r0tl01kq	732	26	as	as	IN
cord-010027-r0tl01kq	732	27	a	a	DT
cord-010027-r0tl01kq	732	28	one	one	CD
cord-010027-r0tl01kq	732	29	-	-	HYPH
cord-010027-r0tl01kq	732	30	step	step	NN
cord-010027-r0tl01kq	732	31	process	process	NN
cord-010027-r0tl01kq	732	32	.	.	.
cord-010027-r0tl01kq	733	1	We	-PRON-	PRP
cord-010027-r0tl01kq	733	2	have	have	VBP
cord-010027-r0tl01kq	733	3	recently	recently	RB
cord-010027-r0tl01kq	733	4	completed	complete	VBN
cord-010027-r0tl01kq	733	5	the	the	DT
cord-010027-r0tl01kq	733	6	clinical	clinical	JJ
cord-010027-r0tl01kq	733	7	validation	validation	NN
cord-010027-r0tl01kq	733	8	of	of	IN
cord-010027-r0tl01kq	733	9	Metasin	Metasin	NNP
cord-010027-r0tl01kq	733	10	,	,	,
cord-010027-r0tl01kq	733	11	an	an	DT
cord-010027-r0tl01kq	733	12	intraoperative	intraoperative	JJ
cord-010027-r0tl01kq	733	13	molecular	molecular	JJ
cord-010027-r0tl01kq	733	14	assay	assay	NN
cord-010027-r0tl01kq	733	15	for	for	IN
cord-010027-r0tl01kq	733	16	sentinel	sentinel	JJ
cord-010027-r0tl01kq	733	17	lymph	lymph	NNP
cord-010027-r0tl01kq	733	18	node	node	NN
cord-010027-r0tl01kq	733	19	analysis	analysis	NN
cord-010027-r0tl01kq	733	20	in	in	IN
cord-010027-r0tl01kq	733	21	breast	breast	NN
cord-010027-r0tl01kq	733	22	cancer	cancer	NN
cord-010027-r0tl01kq	733	23	patients	patient	NNS
cord-010027-r0tl01kq	733	24	(	(	-LRB-
cord-010027-r0tl01kq	733	25	1836	1836	CD
cord-010027-r0tl01kq	733	26	cases	case	NNS
cord-010027-r0tl01kq	733	27	)	)	-RRB-
cord-010027-r0tl01kq	733	28	.	.	.
cord-010027-r0tl01kq	734	1	Method	method	NN
cord-010027-r0tl01kq	734	2	:	:	:
cord-010027-r0tl01kq	735	1	The	the	DT
cord-010027-r0tl01kq	735	2	assay	assay	NN
cord-010027-r0tl01kq	735	3	uses	use	VBZ
cord-010027-r0tl01kq	735	4	2	2	CD
cord-010027-r0tl01kq	735	5	positive	positive	JJ
cord-010027-r0tl01kq	735	6	predictive	predictive	JJ
cord-010027-r0tl01kq	735	7	markers	marker	NNS
cord-010027-r0tl01kq	735	8	and	and	CC
cord-010027-r0tl01kq	735	9	is	be	VBZ
cord-010027-r0tl01kq	735	10	quantitative	quantitative	JJ
cord-010027-r0tl01kq	735	11	,	,	,
cord-010027-r0tl01kq	735	12	enabling	enable	VBG
cord-010027-r0tl01kq	735	13	the	the	DT
cord-010027-r0tl01kq	735	14	prediction	prediction	NN
cord-010027-r0tl01kq	735	15	of	of	IN
cord-010027-r0tl01kq	735	16	tumour	tumour	NN
cord-010027-r0tl01kq	735	17	volume	volume	NN
cord-010027-r0tl01kq	735	18	using	use	VBG
cord-010027-r0tl01kq	735	19	2	2	CD
cord-010027-r0tl01kq	735	20	markers	marker	NNS
cord-010027-r0tl01kq	735	21	CK19	CK19	NNP
cord-010027-r0tl01kq	735	22	and	and	CC
cord-010027-r0tl01kq	735	23	Mammaglobin	Mammaglobin	NNP
cord-010027-r0tl01kq	735	24	.	.	.
cord-010027-r0tl01kq	736	1	In	in	IN
cord-010027-r0tl01kq	736	2	this	this	DT
cord-010027-r0tl01kq	736	3	study	study	NN
cord-010027-r0tl01kq	736	4	group	group	NN
cord-010027-r0tl01kq	736	5	,	,	,
cord-010027-r0tl01kq	736	6	439	439	CD
cord-010027-r0tl01kq	736	7	patients	patient	NNS
cord-010027-r0tl01kq	736	8	had	have	VBD
cord-010027-r0tl01kq	736	9	positive	positive	JJ
cord-010027-r0tl01kq	736	10	sentinel	sentinel	JJ
cord-010027-r0tl01kq	736	11	nodes	node	NNS
cord-010027-r0tl01kq	736	12	and	and	CC
cord-010027-r0tl01kq	736	13	444	444	CD
cord-010027-r0tl01kq	736	14	cases	case	NNS
cord-010027-r0tl01kq	736	15	underwent	undergo	VBD
cord-010027-r0tl01kq	736	16	axillary	axillary	JJ
cord-010027-r0tl01kq	736	17	clearance	clearance	NN
cord-010027-r0tl01kq	736	18	.	.	.
cord-010027-r0tl01kq	737	1	Of	of	IN
cord-010027-r0tl01kq	737	2	the	the	DT
cord-010027-r0tl01kq	737	3	axillary	axillary	JJ
cord-010027-r0tl01kq	737	4	clearance	clearance	NN
cord-010027-r0tl01kq	737	5	cases	case	NNS
cord-010027-r0tl01kq	737	6	,	,	,
cord-010027-r0tl01kq	737	7	26	26	CD
cord-010027-r0tl01kq	737	8	%	%	NN
cord-010027-r0tl01kq	737	9	contained	contain	VBD
cord-010027-r0tl01kq	737	10	positive	positive	JJ
cord-010027-r0tl01kq	737	11	lymph	lymph	NN
cord-010027-r0tl01kq	737	12	nodes	node	NNS
cord-010027-r0tl01kq	737	13	.	.	.
cord-010027-r0tl01kq	738	1	84	84	CD
cord-010027-r0tl01kq	738	2	%	%	NN
cord-010027-r0tl01kq	738	3	were	be	VBD
cord-010027-r0tl01kq	738	4	sentinel	sentinel	JJ
cord-010027-r0tl01kq	738	5	node	node	NN
cord-010027-r0tl01kq	738	6	(	(	-LRB-
cord-010027-r0tl01kq	738	7	SNB	SNB	NNP
cord-010027-r0tl01kq	738	8	)	)	-RRB-
cord-010027-r0tl01kq	738	9	macrometastases	macrometastase	NNS
cord-010027-r0tl01kq	738	10	,	,	,
cord-010027-r0tl01kq	738	11	5	5	CD
cord-010027-r0tl01kq	738	12	%	%	NN
cord-010027-r0tl01kq	738	13	were	be	VBD
cord-010027-r0tl01kq	738	14	SNB	SNB	NNP
cord-010027-r0tl01kq	738	15	micrometastases	micrometastase	NNS
cord-010027-r0tl01kq	738	16	and	and	CC
cord-010027-r0tl01kq	738	17	11	11	CD
cord-010027-r0tl01kq	738	18	%	%	NN
cord-010027-r0tl01kq	738	19	were	be	VBD
cord-010027-r0tl01kq	738	20	SNB	SNB	NNP
cord-010027-r0tl01kq	738	21	negative	negative	JJ
cord-010027-r0tl01kq	738	22	or	or	CC
cord-010027-r0tl01kq	738	23	contained	contain	VBN
cord-010027-r0tl01kq	738	24	isolated	isolated	JJ
cord-010027-r0tl01kq	738	25	tumour	tumour	NN
cord-010027-r0tl01kq	738	26	cells	cell	NNS
cord-010027-r0tl01kq	738	27	.	.	.
cord-010027-r0tl01kq	739	1	Informative	informative	JJ
cord-010027-r0tl01kq	739	2	data	datum	NNS
cord-010027-r0tl01kq	739	3	was	be	VBD
cord-010027-r0tl01kq	739	4	available	available	JJ
cord-010027-r0tl01kq	739	5	for	for	IN
cord-010027-r0tl01kq	739	6	sentinel	sentinel	JJ
cord-010027-r0tl01kq	739	7	nodes	node	NNS
cord-010027-r0tl01kq	739	8	from	from	IN
cord-010027-r0tl01kq	739	9	125	125	CD
cord-010027-r0tl01kq	739	10	positive	positive	JJ
cord-010027-r0tl01kq	739	11	cases	case	NNS
cord-010027-r0tl01kq	739	12	.	.	.
cord-010027-r0tl01kq	740	1	Results	result	NNS
cord-010027-r0tl01kq	740	2	:	:	:
cord-010027-r0tl01kq	741	1	Using	use	VBG
cord-010027-r0tl01kq	741	2	the	the	DT
cord-010027-r0tl01kq	741	3	qPCR	qpcr	NN
cord-010027-r0tl01kq	741	4	values	value	NNS
cord-010027-r0tl01kq	741	5	(	(	-LRB-
cord-010027-r0tl01kq	741	6	from	from	IN
cord-010027-r0tl01kq	741	7	Metasin	Metasin	NNP
cord-010027-r0tl01kq	741	8	assays	assay	NNS
cord-010027-r0tl01kq	741	9	using	use	VBG
cord-010027-r0tl01kq	741	10	standardised	standardised	JJ
cord-010027-r0tl01kq	741	11	pre	pre	NN
cord-010027-r0tl01kq	741	12	-	-	NNS
cord-010027-r0tl01kq	741	13	mixes	mix	NNS
cord-010027-r0tl01kq	741	14	)	)	-RRB-
cord-010027-r0tl01kq	741	15	and	and	CC
cord-010027-r0tl01kq	741	16	clinical	clinical	JJ
cord-010027-r0tl01kq	741	17	axillary	axillary	JJ
cord-010027-r0tl01kq	741	18	clearance	clearance	NN
cord-010027-r0tl01kq	741	19	data	datum	NNS
cord-010027-r0tl01kq	741	20	,	,	,
cord-010027-r0tl01kq	741	21	the	the	DT
cord-010027-r0tl01kq	741	22	cases	case	NNS
cord-010027-r0tl01kq	741	23	have	have	VBP
cord-010027-r0tl01kq	741	24	been	be	VBN
cord-010027-r0tl01kq	741	25	stratified	stratify	VBN
cord-010027-r0tl01kq	741	26	on	on	IN
cord-010027-r0tl01kq	741	27	the	the	DT
cord-010027-r0tl01kq	741	28	basis	basis	NN
cord-010027-r0tl01kq	741	29	of	of	IN
cord-010027-r0tl01kq	741	30	the	the	DT
cord-010027-r0tl01kq	741	31	involvement	involvement	NN
cord-010027-r0tl01kq	741	32	of	of	IN
cord-010027-r0tl01kq	741	33	other	other	JJ
cord-010027-r0tl01kq	741	34	axillary	axillary	JJ
cord-010027-r0tl01kq	741	35	nodes	node	NNS
cord-010027-r0tl01kq	741	36	.	.	.
cord-010027-r0tl01kq	742	1	We	-PRON-	PRP
cord-010027-r0tl01kq	742	2	have	have	VBP
cord-010027-r0tl01kq	742	3	shown	show	VBN
cord-010027-r0tl01kq	742	4	a	a	DT
cord-010027-r0tl01kq	742	5	three	three	CD
cord-010027-r0tl01kq	742	6	-	-	HYPH
cord-010027-r0tl01kq	742	7	tiered	tiered	JJ
cord-010027-r0tl01kq	742	8	predictive	predictive	JJ
cord-010027-r0tl01kq	742	9	grouping	grouping	NN
cord-010027-r0tl01kq	742	10	exists	exist	VBZ
cord-010027-r0tl01kq	742	11	:	:	:
cord-010027-r0tl01kq	743	1	Group	Group	NNP
cord-010027-r0tl01kq	743	2	A	A	NNP
cord-010027-r0tl01kq	743	3	includes	include	VBZ
cord-010027-r0tl01kq	743	4	low	low	JJ
cord-010027-r0tl01kq	743	5	tumour	tumour	NN
cord-010027-r0tl01kq	743	6	volume	volume	NN
cord-010027-r0tl01kq	743	7	disease	disease	NN
cord-010027-r0tl01kq	743	8	with	with	IN
cord-010027-r0tl01kq	743	9	a	a	DT
cord-010027-r0tl01kq	743	10	nodal	nodal	JJ
cord-010027-r0tl01kq	743	11	positivity	positivity	NN
cord-010027-r0tl01kq	743	12	of	of	IN
cord-010027-r0tl01kq	743	13	25	25	CD
cord-010027-r0tl01kq	743	14	%	%	NN
cord-010027-r0tl01kq	743	15	within	within	IN
cord-010027-r0tl01kq	743	16	the	the	DT
cord-010027-r0tl01kq	743	17	axilla	axilla	NN
cord-010027-r0tl01kq	743	18	(	(	-LRB-
cord-010027-r0tl01kq	743	19	n=16	n=16	NNP
cord-010027-r0tl01kq	743	20	)	)	-RRB-
cord-010027-r0tl01kq	743	21	:	:	:
cord-010027-r0tl01kq	744	1	Group	Group	NNP
cord-010027-r0tl01kq	744	2	B	B	NNP
cord-010027-r0tl01kq	744	3	with	with	IN
cord-010027-r0tl01kq	744	4	a	a	DT
cord-010027-r0tl01kq	744	5	44	44	CD
cord-010027-r0tl01kq	744	6	%	%	NN
cord-010027-r0tl01kq	744	7	positivity	positivity	NN
cord-010027-r0tl01kq	744	8	of	of	IN
cord-010027-r0tl01kq	744	9	other	other	JJ
cord-010027-r0tl01kq	744	10	nodal	nodal	JJ
cord-010027-r0tl01kq	744	11	involvement	involvement	NN
cord-010027-r0tl01kq	744	12	(	(	-LRB-
cord-010027-r0tl01kq	744	13	n=80	n=80	NNP
cord-010027-r0tl01kq	744	14	)	)	-RRB-
cord-010027-r0tl01kq	744	15	and	and	CC
cord-010027-r0tl01kq	744	16	Group	Group	NNP
cord-010027-r0tl01kq	744	17	C	C	NNP
cord-010027-r0tl01kq	744	18	with	with	IN
cord-010027-r0tl01kq	744	19	positivity	positivity	NN
cord-010027-r0tl01kq	744	20	of	of	IN
cord-010027-r0tl01kq	744	21	73	73	CD
cord-010027-r0tl01kq	744	22	%	%	NN
cord-010027-r0tl01kq	744	23	of	of	IN
cord-010027-r0tl01kq	744	24	axillary	axillary	JJ
cord-010027-r0tl01kq	744	25	clearances	clearance	NNS
cord-010027-r0tl01kq	744	26	(	(	-LRB-
cord-010027-r0tl01kq	744	27	n=29	n=29	NNP
cord-010027-r0tl01kq	744	28	)	)	-RRB-
cord-010027-r0tl01kq	744	29	.	.	.
cord-010027-r0tl01kq	745	1	The	the	DT
cord-010027-r0tl01kq	745	2	clustering	clustering	NN
cord-010027-r0tl01kq	745	3	of	of	IN
cord-010027-r0tl01kq	745	4	the	the	DT
cord-010027-r0tl01kq	745	5	Metasin	Metasin	NNP
cord-010027-r0tl01kq	745	6	data	data	NN
cord-010027-r0tl01kq	745	7	is	be	VBZ
cord-010027-r0tl01kq	745	8	dependent	dependent	JJ
cord-010027-r0tl01kq	745	9	on	on	IN
cord-010027-r0tl01kq	745	10	the	the	DT
cord-010027-r0tl01kq	745	11	qPCR	qpcr	NN
cord-010027-r0tl01kq	745	12	results	result	NNS
cord-010027-r0tl01kq	745	13	and	and	CC
cord-010027-r0tl01kq	745	14	shows	show	VBZ
cord-010027-r0tl01kq	745	15	that	that	IN
cord-010027-r0tl01kq	745	16	the	the	DT
cord-010027-r0tl01kq	745	17	cases	case	NNS
cord-010027-r0tl01kq	745	18	can	can	MD
cord-010027-r0tl01kq	745	19	be	be	VB
cord-010027-r0tl01kq	745	20	sub	sub	NN
cord-010027-r0tl01kq	745	21	-	-	JJ
cord-010027-r0tl01kq	745	22	grouped	group	VBN
cord-010027-r0tl01kq	745	23	to	to	TO
cord-010027-r0tl01kq	745	24	provide	provide	VB
cord-010027-r0tl01kq	745	25	a	a	DT
cord-010027-r0tl01kq	745	26	probability	probability	NN
cord-010027-r0tl01kq	745	27	basis	basis	NN
cord-010027-r0tl01kq	745	28	for	for	IN
cord-010027-r0tl01kq	745	29	prediction	prediction	NN
cord-010027-r0tl01kq	745	30	of	of	IN
cord-010027-r0tl01kq	745	31	axillary	axillary	JJ
cord-010027-r0tl01kq	745	32	nodal	nodal	JJ
cord-010027-r0tl01kq	745	33	involvement	involvement	NN
cord-010027-r0tl01kq	745	34	;	;	,
cord-010027-r0tl01kq	745	35	dependent	dependent	JJ
cord-010027-r0tl01kq	745	36	on	on	IN
cord-010027-r0tl01kq	745	37	the	the	DT
cord-010027-r0tl01kq	745	38	qPCR	qpcr	JJ
cord-010027-r0tl01kq	745	39	cut	cut	VBN
cord-010027-r0tl01kq	745	40	offs	off	NNS
cord-010027-r0tl01kq	745	41	.	.	.
cord-010027-r0tl01kq	746	1	This	this	DT
cord-010027-r0tl01kq	746	2	gives	give	VBZ
cord-010027-r0tl01kq	746	3	the	the	DT
cord-010027-r0tl01kq	746	4	patient	patient	NN
cord-010027-r0tl01kq	746	5	and	and	CC
cord-010027-r0tl01kq	746	6	surgeon	surgeon	NN
cord-010027-r0tl01kq	746	7	a	a	DT
cord-010027-r0tl01kq	746	8	statistical	statistical	JJ
cord-010027-r0tl01kq	746	9	basis	basis	NN
cord-010027-r0tl01kq	746	10	for	for	IN
cord-010027-r0tl01kq	746	11	determining	determine	VBG
cord-010027-r0tl01kq	746	12	the	the	DT
cord-010027-r0tl01kq	746	13	likelihood	likelihood	NN
cord-010027-r0tl01kq	746	14	of	of	IN
cord-010027-r0tl01kq	746	15	other	other	JJ
cord-010027-r0tl01kq	746	16	axillary	axillary	JJ
cord-010027-r0tl01kq	746	17	nodal	nodal	JJ
cord-010027-r0tl01kq	746	18	disease	disease	NN
cord-010027-r0tl01kq	746	19	.	.	.
cord-010027-r0tl01kq	747	1	Sequencing	sequencing	NN
cord-010027-r0tl01kq	747	2	of	of	IN
cord-010027-r0tl01kq	747	3	the	the	DT
cord-010027-r0tl01kq	747	4	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	747	5	and	and	CC
cord-010027-r0tl01kq	747	6	BRCA2	BRCA2	NNP
cord-010027-r0tl01kq	747	7	genes	gene	NNS
cord-010027-r0tl01kq	747	8	has	have	VBZ
cord-010027-r0tl01kq	747	9	long	long	RB
cord-010027-r0tl01kq	747	10	been	be	VBN
cord-010027-r0tl01kq	747	11	used	use	VBN
cord-010027-r0tl01kq	747	12	in	in	IN
cord-010027-r0tl01kq	747	13	genetics	genetics	NN
cord-010027-r0tl01kq	747	14	laboratories	laboratory	NNS
cord-010027-r0tl01kq	747	15	to	to	TO
cord-010027-r0tl01kq	747	16	identify	identify	VB
cord-010027-r0tl01kq	747	17	cases	case	NNS
cord-010027-r0tl01kq	747	18	of	of	IN
cord-010027-r0tl01kq	747	19	familial	familial	JJ
cord-010027-r0tl01kq	747	20	breast	breast	NN
cord-010027-r0tl01kq	747	21	and	and	CC
cord-010027-r0tl01kq	747	22	ovarian	ovarian	JJ
cord-010027-r0tl01kq	747	23	cancer	cancer	NN
cord-010027-r0tl01kq	747	24	.	.	.
cord-010027-r0tl01kq	748	1	However	however	RB
cord-010027-r0tl01kq	748	2	,	,	,
cord-010027-r0tl01kq	748	3	the	the	DT
cord-010027-r0tl01kq	748	4	advent	advent	NN
cord-010027-r0tl01kq	748	5	of	of	IN
cord-010027-r0tl01kq	748	6	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	748	7	for	for	IN
cord-010027-r0tl01kq	748	8	ovarian	ovarian	JJ
cord-010027-r0tl01kq	748	9	cancer	cancer	NN
cord-010027-r0tl01kq	748	10	based	base	VBN
cord-010027-r0tl01kq	748	11	on	on	IN
cord-010027-r0tl01kq	748	12	PARP	PARP	NNP
cord-010027-r0tl01kq	748	13	inhibitors	inhibitor	NNS
cord-010027-r0tl01kq	748	14	,	,	,
cord-010027-r0tl01kq	748	15	which	which	WDT
cord-010027-r0tl01kq	748	16	requires	require	VBZ
cord-010027-r0tl01kq	748	17	the	the	DT
cord-010027-r0tl01kq	748	18	presence	presence	NN
cord-010027-r0tl01kq	748	19	of	of	IN
cord-010027-r0tl01kq	748	20	a	a	DT
cord-010027-r0tl01kq	748	21	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	748	22	or	or	CC
cord-010027-r0tl01kq	748	23	BRCA2	brca2	NN
cord-010027-r0tl01kq	748	24	mutation	mutation	NN
cord-010027-r0tl01kq	748	25	,	,	,
cord-010027-r0tl01kq	748	26	is	be	VBZ
cord-010027-r0tl01kq	748	27	turning	turn	VBG
cord-010027-r0tl01kq	748	28	this	this	DT
cord-010027-r0tl01kq	748	29	specialist	specialist	JJ
cord-010027-r0tl01kq	748	30	test	test	NN
cord-010027-r0tl01kq	748	31	into	into	IN
cord-010027-r0tl01kq	748	32	a	a	DT
cord-010027-r0tl01kq	748	33	commonly	commonly	RB
cord-010027-r0tl01kq	748	34	-	-	HYPH
cord-010027-r0tl01kq	748	35	applied	apply	VBN
cord-010027-r0tl01kq	748	36	companion	companion	NN
cord-010027-r0tl01kq	748	37	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	748	38	.	.	.
cord-010027-r0tl01kq	749	1	At	at	IN
cord-010027-r0tl01kq	749	2	the	the	DT
cord-010027-r0tl01kq	749	3	same	same	JJ
cord-010027-r0tl01kq	749	4	time	time	NN
cord-010027-r0tl01kq	749	5	,	,	,
cord-010027-r0tl01kq	749	6	the	the	DT
cord-010027-r0tl01kq	749	7	introduction	introduction	NN
cord-010027-r0tl01kq	749	8	of	of	IN
cord-010027-r0tl01kq	749	9	new	new	JJ
cord-010027-r0tl01kq	749	10	DNA	dna	NN
cord-010027-r0tl01kq	749	11	sequencing	sequencing	NN
cord-010027-r0tl01kq	749	12	technologies	technology	NNS
cord-010027-r0tl01kq	749	13	is	be	VBZ
cord-010027-r0tl01kq	749	14	posing	pose	VBG
cord-010027-r0tl01kq	749	15	challenges	challenge	NNS
cord-010027-r0tl01kq	749	16	even	even	RB
cord-010027-r0tl01kq	749	17	for	for	IN
cord-010027-r0tl01kq	749	18	experienced	experienced	JJ
cord-010027-r0tl01kq	749	19	genetics	genetics	NN
cord-010027-r0tl01kq	749	20	laboratories	laboratory	NNS
cord-010027-r0tl01kq	749	21	.	.	.
cord-010027-r0tl01kq	750	1	EMQN	EMQN	NNP
cord-010027-r0tl01kq	750	2	has	have	VBZ
cord-010027-r0tl01kq	750	3	been	be	VBN
cord-010027-r0tl01kq	750	4	providing	provide	VBG
cord-010027-r0tl01kq	750	5	EQA	EQA	NNP
cord-010027-r0tl01kq	750	6	of	of	IN
cord-010027-r0tl01kq	750	7	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	750	8	and	and	CC
cord-010027-r0tl01kq	750	9	BRCA2	BRCA2	NNP
cord-010027-r0tl01kq	751	1	gene	gene	NN
cord-010027-r0tl01kq	751	2	sequencing	sequence	VBG
cord-010027-r0tl01kq	751	3	world	world	NN
cord-010027-r0tl01kq	751	4	-	-	HYPH
cord-010027-r0tl01kq	751	5	wide	wide	RB
cord-010027-r0tl01kq	751	6	for	for	IN
cord-010027-r0tl01kq	751	7	15	15	CD
cord-010027-r0tl01kq	751	8	years	year	NNS
cord-010027-r0tl01kq	751	9	.	.	.
cord-010027-r0tl01kq	752	1	The	the	DT
cord-010027-r0tl01kq	752	2	rate	rate	NN
cord-010027-r0tl01kq	752	3	of	of	IN
cord-010027-r0tl01kq	752	4	serious	serious	JJ
cord-010027-r0tl01kq	752	5	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	752	6	errors	error	NNS
cord-010027-r0tl01kq	752	7	has	have	VBZ
cord-010027-r0tl01kq	752	8	varied	vary	VBN
cord-010027-r0tl01kq	752	9	from	from	IN
cord-010027-r0tl01kq	752	10	year	year	NN
cord-010027-r0tl01kq	752	11	to	to	IN
cord-010027-r0tl01kq	752	12	year	year	NN
cord-010027-r0tl01kq	752	13	,	,	,
cord-010027-r0tl01kq	752	14	but	but	CC
cord-010027-r0tl01kq	752	15	the	the	DT
cord-010027-r0tl01kq	752	16	mean	mean	NN
cord-010027-r0tl01kq	752	17	has	have	VBZ
cord-010027-r0tl01kq	752	18	hovered	hover	VBN
cord-010027-r0tl01kq	752	19	stubbornly	stubbornly	RB
cord-010027-r0tl01kq	752	20	around	around	IN
cord-010027-r0tl01kq	752	21	3	3	CD
cord-010027-r0tl01kq	752	22	%	%	NN
cord-010027-r0tl01kq	752	23	.	.	.
cord-010027-r0tl01kq	753	1	In	in	IN
cord-010027-r0tl01kq	753	2	EQA	EQA	NNP
cord-010027-r0tl01kq	753	3	,	,	,
cord-010027-r0tl01kq	753	4	just	just	RB
cord-010027-r0tl01kq	753	5	3	3	CD
cord-010027-r0tl01kq	753	6	samples	sample	NNS
cord-010027-r0tl01kq	753	7	per	per	IN
cord-010027-r0tl01kq	753	8	year	year	NN
cord-010027-r0tl01kq	753	9	are	be	VBP
cord-010027-r0tl01kq	753	10	sent	send	VBN
cord-010027-r0tl01kq	753	11	out	out	RP
cord-010027-r0tl01kq	753	12	,	,	,
cord-010027-r0tl01kq	753	13	and	and	CC
cord-010027-r0tl01kq	753	14	the	the	DT
cord-010027-r0tl01kq	753	15	quality	quality	NN
cord-010027-r0tl01kq	753	16	and	and	CC
cord-010027-r0tl01kq	753	17	experience	experience	NN
cord-010027-r0tl01kq	753	18	of	of	IN
cord-010027-r0tl01kq	753	19	participating	participate	VBG
cord-010027-r0tl01kq	753	20	laboratories	laboratory	NNS
cord-010027-r0tl01kq	753	21	varies	vary	VBZ
cord-010027-r0tl01kq	753	22	greatly	greatly	RB
cord-010027-r0tl01kq	753	23	.	.	.
cord-010027-r0tl01kq	754	1	We	-PRON-	PRP
cord-010027-r0tl01kq	754	2	recently	recently	RB
cord-010027-r0tl01kq	754	3	carried	carry	VBD
cord-010027-r0tl01kq	754	4	out	out	RP
cord-010027-r0tl01kq	754	5	a	a	DT
cord-010027-r0tl01kq	754	6	collaborative	collaborative	JJ
cord-010027-r0tl01kq	754	7	study	study	NN
cord-010027-r0tl01kq	754	8	to	to	TO
cord-010027-r0tl01kq	754	9	measure	measure	VB
cord-010027-r0tl01kq	754	10	the	the	DT
cord-010027-r0tl01kq	754	11	quality	quality	NN
cord-010027-r0tl01kq	754	12	of	of	IN
cord-010027-r0tl01kq	754	13	BRCA	BRCA	NNP
cord-010027-r0tl01kq	754	14	gene	gene	NN
cord-010027-r0tl01kq	754	15	sequencing	sequencing	NN
cord-010027-r0tl01kq	754	16	by	by	IN
cord-010027-r0tl01kq	754	17	traditional	traditional	JJ
cord-010027-r0tl01kq	754	18	and	and	CC
cord-010027-r0tl01kq	754	19	new	new	JJ
cord-010027-r0tl01kq	754	20	methods	method	NNS
cord-010027-r0tl01kq	754	21	in	in	IN
cord-010027-r0tl01kq	754	22	20	20	CD
cord-010027-r0tl01kq	754	23	experienced	experienced	JJ
cord-010027-r0tl01kq	754	24	,	,	,
cord-010027-r0tl01kq	754	25	expert	expert	NN
cord-010027-r0tl01kq	754	26	laboratories	laboratory	NNS
cord-010027-r0tl01kq	754	27	from	from	IN
cord-010027-r0tl01kq	754	28	11	11	CD
cord-010027-r0tl01kq	754	29	countries	country	NNS
cord-010027-r0tl01kq	754	30	.	.	.
cord-010027-r0tl01kq	755	1	Ten	ten	CD
cord-010027-r0tl01kq	755	2	DNA	dna	NN
cord-010027-r0tl01kq	755	3	samples	sample	NNS
cord-010027-r0tl01kq	755	4	(	(	-LRB-
cord-010027-r0tl01kq	755	5	8	8	CD
cord-010027-r0tl01kq	755	6	with	with	IN
cord-010027-r0tl01kq	755	7	pathogenic	pathogenic	JJ
cord-010027-r0tl01kq	755	8	mutations	mutation	NNS
cord-010027-r0tl01kq	755	9	,	,	,
cord-010027-r0tl01kq	755	10	2	2	CD
cord-010027-r0tl01kq	755	11	with	with	IN
cord-010027-r0tl01kq	755	12	normal	normal	JJ
cord-010027-r0tl01kq	755	13	DNA	dna	NN
cord-010027-r0tl01kq	755	14	sequence	sequence	NN
cord-010027-r0tl01kq	755	15	)	)	-RRB-
cord-010027-r0tl01kq	755	16	were	be	VBD
cord-010027-r0tl01kq	755	17	sent	send	VBN
cord-010027-r0tl01kq	755	18	to	to	IN
cord-010027-r0tl01kq	755	19	each	each	DT
cord-010027-r0tl01kq	755	20	laboratory	laboratory	NN
cord-010027-r0tl01kq	755	21	.	.	.
cord-010027-r0tl01kq	756	1	Ten	ten	CD
cord-010027-r0tl01kq	756	2	labs	lab	NNS
cord-010027-r0tl01kq	756	3	used	use	VBD
cord-010027-r0tl01kq	756	4	next	next	JJ
cord-010027-r0tl01kq	756	5	-	-	HYPH
cord-010027-r0tl01kq	756	6	generation	generation	NN
cord-010027-r0tl01kq	756	7	sequencing	sequencing	NN
cord-010027-r0tl01kq	756	8	(	(	-LRB-
cord-010027-r0tl01kq	756	9	NGS	NGS	NNP
cord-010027-r0tl01kq	756	10	)	)	-RRB-
cord-010027-r0tl01kq	756	11	alone	alone	RB
cord-010027-r0tl01kq	756	12	,	,	,
cord-010027-r0tl01kq	756	13	3	3	CD
cord-010027-r0tl01kq	756	14	used	use	VBD
cord-010027-r0tl01kq	756	15	Sanger	Sanger	NNP
cord-010027-r0tl01kq	756	16	sequencing	sequencing	NN
cord-010027-r0tl01kq	756	17	alone	alone	RB
cord-010027-r0tl01kq	756	18	,	,	,
cord-010027-r0tl01kq	756	19	and	and	CC
cord-010027-r0tl01kq	756	20	the	the	DT
cord-010027-r0tl01kq	756	21	others	other	NNS
cord-010027-r0tl01kq	756	22	used	use	VBD
cord-010027-r0tl01kq	756	23	combinations	combination	NNS
cord-010027-r0tl01kq	756	24	of	of	IN
cord-010027-r0tl01kq	756	25	Sanger	Sanger	NNP
cord-010027-r0tl01kq	756	26	sequencing	sequencing	NN
cord-010027-r0tl01kq	756	27	,	,	,
cord-010027-r0tl01kq	756	28	NGS	NGS	NNP
cord-010027-r0tl01kq	756	29	,	,	,
cord-010027-r0tl01kq	756	30	MLPA	MLPA	NNP
cord-010027-r0tl01kq	756	31	and	and	CC
cord-010027-r0tl01kq	756	32	other	other	JJ
cord-010027-r0tl01kq	756	33	technologies	technology	NNS
cord-010027-r0tl01kq	756	34	.	.	.
cord-010027-r0tl01kq	757	1	Seventeen	seventeen	CD
cord-010027-r0tl01kq	757	2	(	(	-LRB-
cord-010027-r0tl01kq	757	3	85	85	CD
cord-010027-r0tl01kq	757	4	%	%	NN
cord-010027-r0tl01kq	757	5	)	)	-RRB-
cord-010027-r0tl01kq	757	6	of	of	IN
cord-010027-r0tl01kq	757	7	labs	lab	NNS
cord-010027-r0tl01kq	757	8	identified	identify	VBD
cord-010027-r0tl01kq	757	9	all	all	DT
cord-010027-r0tl01kq	757	10	clinically	clinically	RB
cord-010027-r0tl01kq	757	11	-	-	HYPH
cord-010027-r0tl01kq	757	12	significant	significant	JJ
cord-010027-r0tl01kq	757	13	variants	variant	NNS
cord-010027-r0tl01kq	757	14	on	on	IN
cord-010027-r0tl01kq	757	15	all	all	DT
cord-010027-r0tl01kq	757	16	10	10	CD
cord-010027-r0tl01kq	757	17	samples	sample	NNS
cord-010027-r0tl01kq	757	18	.	.	.
cord-010027-r0tl01kq	758	1	Four	four	CD
cord-010027-r0tl01kq	758	2	false	false	JJ
cord-010027-r0tl01kq	758	3	negative	negative	JJ
cord-010027-r0tl01kq	758	4	results	result	NNS
cord-010027-r0tl01kq	758	5	were	be	VBD
cord-010027-r0tl01kq	758	6	reported	report	VBN
cord-010027-r0tl01kq	758	7	by	by	IN
cord-010027-r0tl01kq	758	8	3	3	CD
cord-010027-r0tl01kq	758	9	labs	lab	NNS
cord-010027-r0tl01kq	758	10	.	.	.
cord-010027-r0tl01kq	759	1	Two	two	CD
cord-010027-r0tl01kq	759	2	were	be	VBD
cord-010027-r0tl01kq	759	3	due	due	JJ
cord-010027-r0tl01kq	759	4	to	to	IN
cord-010027-r0tl01kq	759	5	deficiencies	deficiency	NNS
cord-010027-r0tl01kq	759	6	in	in	IN
cord-010027-r0tl01kq	759	7	the	the	DT
cord-010027-r0tl01kq	759	8	bioinformatics	bioinformatics	NN
cord-010027-r0tl01kq	759	9	pipeline	pipeline	NN
cord-010027-r0tl01kq	759	10	of	of	IN
cord-010027-r0tl01kq	759	11	the	the	DT
cord-010027-r0tl01kq	759	12	NGS	NGS	NNP
cord-010027-r0tl01kq	759	13	process	process	NN
cord-010027-r0tl01kq	759	14	,	,	,
cord-010027-r0tl01kq	759	15	while	while	IN
cord-010027-r0tl01kq	759	16	2	2	CD
cord-010027-r0tl01kq	759	17	were	be	VBD
cord-010027-r0tl01kq	759	18	attributed	attribute	VBN
cord-010027-r0tl01kq	759	19	to	to	IN
cord-010027-r0tl01kq	759	20	a	a	DT
cord-010027-r0tl01kq	759	21	sample	sample	NN
cord-010027-r0tl01kq	759	22	swap	swap	NN
cord-010027-r0tl01kq	759	23	,	,	,
cord-010027-r0tl01kq	759	24	and	and	CC
cord-010027-r0tl01kq	759	25	incorrect	incorrect	JJ
cord-010027-r0tl01kq	759	26	interpretation	interpretation	NN
cord-010027-r0tl01kq	759	27	of	of	IN
cord-010027-r0tl01kq	759	28	a	a	DT
cord-010027-r0tl01kq	759	29	melting	melting	NN
cord-010027-r0tl01kq	759	30	profile	profile	NN
cord-010027-r0tl01kq	759	31	.	.	.
cord-010027-r0tl01kq	760	1	No	no	DT
cord-010027-r0tl01kq	760	2	significant	significant	JJ
cord-010027-r0tl01kq	760	3	trend	trend	NN
cord-010027-r0tl01kq	760	4	was	be	VBD
cord-010027-r0tl01kq	760	5	identified	identify	VBN
cord-010027-r0tl01kq	760	6	with	with	IN
cord-010027-r0tl01kq	760	7	respect	respect	NN
cord-010027-r0tl01kq	760	8	to	to	IN
cord-010027-r0tl01kq	760	9	the	the	DT
cord-010027-r0tl01kq	760	10	genotyping	genotyping	NN
cord-010027-r0tl01kq	760	11	accuracy	accuracy	NN
cord-010027-r0tl01kq	760	12	of	of	IN
cord-010027-r0tl01kq	760	13	the	the	DT
cord-010027-r0tl01kq	760	14	different	different	JJ
cord-010027-r0tl01kq	760	15	methodologies	methodology	NNS
cord-010027-r0tl01kq	760	16	used	use	VBN
cord-010027-r0tl01kq	760	17	.	.	.
cord-010027-r0tl01kq	761	1	The	the	DT
cord-010027-r0tl01kq	761	2	observed	observed	JJ
cord-010027-r0tl01kq	761	3	error	error	NN
cord-010027-r0tl01kq	761	4	rate	rate	NN
cord-010027-r0tl01kq	761	5	of	of	IN
cord-010027-r0tl01kq	761	6	2	2	CD
cord-010027-r0tl01kq	761	7	%	%	NN
cord-010027-r0tl01kq	761	8	amongst	amongst	IN
cord-010027-r0tl01kq	761	9	expert	expert	JJ
cord-010027-r0tl01kq	761	10	laboratories	laboratory	NNS
cord-010027-r0tl01kq	761	11	indicates	indicate	VBZ
cord-010027-r0tl01kq	761	12	the	the	DT
cord-010027-r0tl01kq	761	13	complex	complex	JJ
cord-010027-r0tl01kq	761	14	and	and	CC
cord-010027-r0tl01kq	761	15	challenging	challenging	JJ
cord-010027-r0tl01kq	761	16	nature	nature	NN
cord-010027-r0tl01kq	761	17	of	of	IN
cord-010027-r0tl01kq	761	18	this	this	DT
cord-010027-r0tl01kq	761	19	kind	kind	NN
cord-010027-r0tl01kq	761	20	of	of	IN
cord-010027-r0tl01kq	761	21	testing	testing	NN
cord-010027-r0tl01kq	761	22	.	.	.
cord-010027-r0tl01kq	762	1	Caution	caution	NN
cord-010027-r0tl01kq	762	2	will	will	MD
cord-010027-r0tl01kq	762	3	be	be	VB
cord-010027-r0tl01kq	762	4	required	require	VBN
cord-010027-r0tl01kq	762	5	when	when	WRB
cord-010027-r0tl01kq	762	6	applying	apply	VBG
cord-010027-r0tl01kq	762	7	these	these	DT
cord-010027-r0tl01kq	762	8	technologies	technology	NNS
cord-010027-r0tl01kq	762	9	to	to	IN
cord-010027-r0tl01kq	762	10	sub	sub	VB
cord-010027-r0tl01kq	762	11	-	-	JJ
cord-010027-r0tl01kq	762	12	optimal	optimal	JJ
cord-010027-r0tl01kq	762	13	FFPE	ffpe	NN
cord-010027-r0tl01kq	762	14	samples	sample	NNS
cord-010027-r0tl01kq	762	15	in	in	IN
cord-010027-r0tl01kq	762	16	Pathology	Pathology	NNP
cord-010027-r0tl01kq	762	17	laboratories	laboratory	NNS
cord-010027-r0tl01kq	762	18	.	.	.
cord-010027-r0tl01kq	763	1	P	p	NN
cord-010027-r0tl01kq	763	2	N	n	CD
cord-010027-r0tl01kq	763	3	Wolstenholme	Wolstenholme	NNP
cord-010027-r0tl01kq	763	4	1	1	CD
cord-010027-r0tl01kq	763	5	;	;	:
cord-010027-r0tl01kq	763	6	SJ	SJ	NNP
cord-010027-r0tl01kq	763	7	Patton	Patton	NNP
cord-010027-r0tl01kq	763	8	1	1	CD
cord-010027-r0tl01kq	763	9	;	;	:
cord-010027-r0tl01kq	763	10	Z	Z	NNP
cord-010027-r0tl01kq	763	11	Deans	Deans	NNPS
cord-010027-r0tl01kq	763	12	2	2	CD
cord-010027-r0tl01kq	763	13	;	;	:
cord-010027-r0tl01kq	763	14	S	S	NNP
cord-010027-r0tl01kq	763	15	Abbs	Abbs	NNP
cord-010027-r0tl01kq	763	16	3	3	CD
cord-010027-r0tl01kq	763	17	;	;	:
cord-010027-r0tl01kq	763	18	J	J	NNP
cord-010027-r0tl01kq	763	19	Coxhead	Coxhead	NNP
cord-010027-r0tl01kq	763	20	4	4	CD
cord-010027-r0tl01kq	763	21	;	;	:
cord-010027-r0tl01kq	763	22	K	K	NNP
cord-010027-r0tl01kq	763	23	Brugger	Brugger	NNP
cord-010027-r0tl01kq	763	24	3	3	CD
cord-010027-r0tl01kq	763	25	;	;	:
cord-010027-r0tl01kq	763	26	P	P	NNP
cord-010027-r0tl01kq	763	27	Westwood	Westwood	NNP
cord-010027-r0tl01kq	763	28	5	5	CD
cord-010027-r0tl01kq	763	29	;	;	:
cord-010027-r0tl01kq	763	30	K	K	NNP
cord-010027-r0tl01kq	763	31	Thomson	Thomson	NNP
cord-010027-r0tl01kq	763	32	6	6	CD
cord-010027-r0tl01kq	763	33	;	;	:
cord-010027-r0tl01kq	763	34	H	H	NNP
cord-010027-r0tl01kq	763	35	Scheffer	Scheffer	NNP
cord-010027-r0tl01kq	763	36	7	7	CD
cord-010027-r0tl01kq	764	1	Next	next	JJ
cord-010027-r0tl01kq	764	2	Generation	generation	NN
cord-010027-r0tl01kq	764	3	Sequencing	Sequencing	NNP
cord-010027-r0tl01kq	764	4	(	(	-LRB-
cord-010027-r0tl01kq	764	5	NGS	NGS	NNP
cord-010027-r0tl01kq	764	6	)	)	-RRB-
cord-010027-r0tl01kq	764	7	is	be	VBZ
cord-010027-r0tl01kq	764	8	increasingly	increasingly	RB
cord-010027-r0tl01kq	764	9	being	be	VBG
cord-010027-r0tl01kq	764	10	introduced	introduce	VBN
cord-010027-r0tl01kq	764	11	into	into	IN
cord-010027-r0tl01kq	764	12	clinical	clinical	JJ
cord-010027-r0tl01kq	764	13	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	764	14	laboratories	laboratory	NNS
cord-010027-r0tl01kq	764	15	worldwide	worldwide	RB
cord-010027-r0tl01kq	764	16	.	.	.
cord-010027-r0tl01kq	765	1	The	the	DT
cord-010027-r0tl01kq	765	2	huge	huge	JJ
cord-010027-r0tl01kq	765	3	amount	amount	NN
cord-010027-r0tl01kq	765	4	of	of	IN
cord-010027-r0tl01kq	765	5	data	datum	NNS
cord-010027-r0tl01kq	765	6	generated	generate	VBN
cord-010027-r0tl01kq	765	7	by	by	IN
cord-010027-r0tl01kq	765	8	NGS	NGS	NNP
cord-010027-r0tl01kq	765	9	can	can	MD
cord-010027-r0tl01kq	765	10	not	not	RB
cord-010027-r0tl01kq	765	11	be	be	VB
cord-010027-r0tl01kq	765	12	duplicated	duplicate	VBN
cord-010027-r0tl01kq	765	13	by	by	IN
cord-010027-r0tl01kq	765	14	alternative	alternative	JJ
cord-010027-r0tl01kq	765	15	methods	method	NNS
cord-010027-r0tl01kq	765	16	for	for	IN
cord-010027-r0tl01kq	765	17	laboratories	laboratory	NNS
cord-010027-r0tl01kq	765	18	to	to	TO
cord-010027-r0tl01kq	765	19	internally	internally	RB
cord-010027-r0tl01kq	765	20	validate	validate	VB
cord-010027-r0tl01kq	765	21	all	all	DT
cord-010027-r0tl01kq	765	22	results	result	NNS
cord-010027-r0tl01kq	765	23	,	,	,
cord-010027-r0tl01kq	765	24	therefore	therefore	RB
cord-010027-r0tl01kq	765	25	external	external	JJ
cord-010027-r0tl01kq	765	26	assessment	assessment	NN
cord-010027-r0tl01kq	765	27	of	of	IN
cord-010027-r0tl01kq	765	28	data	datum	NNS
cord-010027-r0tl01kq	765	29	is	be	VBZ
cord-010027-r0tl01kq	765	30	required	require	VBN
cord-010027-r0tl01kq	765	31	.	.	.
cord-010027-r0tl01kq	766	1	The	the	DT
cord-010027-r0tl01kq	766	2	UK	UK	NNP
cord-010027-r0tl01kq	766	3	National	National	NNP
cord-010027-r0tl01kq	766	4	External	External	NNP
cord-010027-r0tl01kq	766	5	Quality	Quality	NNP
cord-010027-r0tl01kq	766	6	Assessment	Assessment	NNP
cord-010027-r0tl01kq	766	7	Scheme	Scheme	NNP
cord-010027-r0tl01kq	766	8	(	(	-LRB-
cord-010027-r0tl01kq	766	9	UKNEQAS	UKNEQAS	NNP
cord-010027-r0tl01kq	766	10	)	)	-RRB-
cord-010027-r0tl01kq	766	11	for	for	IN
cord-010027-r0tl01kq	766	12	Molecular	Molecular	NNP
cord-010027-r0tl01kq	766	13	Genetics	Genetics	NNP
cord-010027-r0tl01kq	766	14	and	and	CC
cord-010027-r0tl01kq	766	15	the	the	DT
cord-010027-r0tl01kq	766	16	European	European	NNP
cord-010027-r0tl01kq	766	17	Molecular	Molecular	NNP
cord-010027-r0tl01kq	766	18	Genetics	Genetics	NNP
cord-010027-r0tl01kq	766	19	Quality	Quality	NNP
cord-010027-r0tl01kq	766	20	Network	Network	NNP
cord-010027-r0tl01kq	766	21	(	(	-LRB-
cord-010027-r0tl01kq	766	22	EMQN	EMQN	NNP
cord-010027-r0tl01kq	766	23	)	)	-RRB-
cord-010027-r0tl01kq	766	24	have	have	VBP
cord-010027-r0tl01kq	766	25	developed	develop	VBN
cord-010027-r0tl01kq	766	26	a	a	DT
cord-010027-r0tl01kq	766	27	joint	joint	JJ
cord-010027-r0tl01kq	766	28	EQA	eqa	NN
cord-010027-r0tl01kq	766	29	scheme	scheme	NN
cord-010027-r0tl01kq	766	30	for	for	IN
cord-010027-r0tl01kq	766	31	NGS	NGS	NNP
cord-010027-r0tl01kq	766	32	,	,	,
cord-010027-r0tl01kq	766	33	with	with	IN
cord-010027-r0tl01kq	766	34	the	the	DT
cord-010027-r0tl01kq	766	35	aims	aim	NNS
cord-010027-r0tl01kq	766	36	to	to	TO
cord-010027-r0tl01kq	766	37	:	:	:
cord-010027-r0tl01kq	766	38	(	(	-LRB-
cord-010027-r0tl01kq	766	39	a	a	LS
cord-010027-r0tl01kq	766	40	)	)	-RRB-
cord-010027-r0tl01kq	766	41	assess	assess	VB
cord-010027-r0tl01kq	766	42	and	and	CC
cord-010027-r0tl01kq	766	43	improve	improve	VB
cord-010027-r0tl01kq	766	44	quality	quality	NN
cord-010027-r0tl01kq	766	45	;	;	:
cord-010027-r0tl01kq	766	46	(	(	-LRB-
cord-010027-r0tl01kq	766	47	b	b	LS
cord-010027-r0tl01kq	766	48	)	)	-RRB-
cord-010027-r0tl01kq	766	49	enable	enable	VB
cord-010027-r0tl01kq	766	50	laboratories	laboratory	NNS
cord-010027-r0tl01kq	766	51	to	to	TO
cord-010027-r0tl01kq	766	52	benchmark	benchmark	VB
cord-010027-r0tl01kq	766	53	their	-PRON-	PRP$
cord-010027-r0tl01kq	766	54	NGS	NGS	NNP
cord-010027-r0tl01kq	766	55	service	service	NN
cord-010027-r0tl01kq	766	56	against	against	IN
cord-010027-r0tl01kq	766	57	others	other	NNS
cord-010027-r0tl01kq	766	58	and	and	CC
cord-010027-r0tl01kq	766	59	against	against	IN
cord-010027-r0tl01kq	766	60	best	good	JJS
cord-010027-r0tl01kq	766	61	practice	practice	NN
cord-010027-r0tl01kq	766	62	;	;	,
cord-010027-r0tl01kq	766	63	(	(	-LRB-
cord-010027-r0tl01kq	766	64	c	c	NN
cord-010027-r0tl01kq	766	65	)	)	-RRB-
cord-010027-r0tl01kq	766	66	work	work	NN
cord-010027-r0tl01kq	766	67	towards	towards	IN
cord-010027-r0tl01kq	766	68	consistency	consistency	NN
cord-010027-r0tl01kq	766	69	of	of	IN
cord-010027-r0tl01kq	766	70	reporting	report	VBG
cord-010027-r0tl01kq	766	71	clinical	clinical	JJ
cord-010027-r0tl01kq	766	72	results	result	NNS
cord-010027-r0tl01kq	766	73	generated	generate	VBN
cord-010027-r0tl01kq	766	74	by	by	IN
cord-010027-r0tl01kq	766	75	NGS	NGS	NNP
cord-010027-r0tl01kq	766	76	;	;	:
cord-010027-r0tl01kq	766	77	and	and	CC
cord-010027-r0tl01kq	766	78	(	(	-LRB-
cord-010027-r0tl01kq	766	79	d	d	NN
cord-010027-r0tl01kq	766	80	)	)	-RRB-
cord-010027-r0tl01kq	766	81	contribute	contribute	VB
cord-010027-r0tl01kq	766	82	towards	towards	IN
cord-010027-r0tl01kq	766	83	best	good	JJS
cord-010027-r0tl01kq	766	84	practice	practice	NN
cord-010027-r0tl01kq	766	85	.	.	.
cord-010027-r0tl01kq	767	1	EMQN	EMQN	NNP
cord-010027-r0tl01kq	767	2	and	and	CC
cord-010027-r0tl01kq	767	3	UKNEQAS	ukneqa	NNS
cord-010027-r0tl01kq	767	4	offer	offer	VBP
cord-010027-r0tl01kq	767	5	numerous	numerous	JJ
cord-010027-r0tl01kq	767	6	disease	disease	NN
cord-010027-r0tl01kq	767	7	-	-	HYPH
cord-010027-r0tl01kq	767	8	specific	specific	JJ
cord-010027-r0tl01kq	767	9	,	,	,
cord-010027-r0tl01kq	767	10	molecular	molecular	JJ
cord-010027-r0tl01kq	767	11	pathology	pathology	NN
cord-010027-r0tl01kq	767	12	and	and	CC
cord-010027-r0tl01kq	767	13	technical	technical	JJ
cord-010027-r0tl01kq	767	14	EQA	eqa	NN
cord-010027-r0tl01kq	767	15	schemes	scheme	NNS
cord-010027-r0tl01kq	767	16	.	.	.
cord-010027-r0tl01kq	768	1	The	the	DT
cord-010027-r0tl01kq	768	2	objectives	objective	NNS
cord-010027-r0tl01kq	768	3	for	for	IN
cord-010027-r0tl01kq	768	4	developing	develop	VBG
cord-010027-r0tl01kq	768	5	NGS	NGS	NNP
cord-010027-r0tl01kq	768	6	EQA	EQA	NNP
cord-010027-r0tl01kq	768	7	were	be	VBD
cord-010027-r0tl01kq	768	8	to	to	TO
cord-010027-r0tl01kq	768	9	make	make	VB
cord-010027-r0tl01kq	768	10	it	-PRON-	PRP
cord-010027-r0tl01kq	768	11	generic	generic	JJ
cord-010027-r0tl01kq	768	12	(	(	-LRB-
cord-010027-r0tl01kq	768	13	independent	independent	JJ
cord-010027-r0tl01kq	768	14	of	of	IN
cord-010027-r0tl01kq	768	15	genes	gene	NNS
cord-010027-r0tl01kq	768	16	,	,	,
cord-010027-r0tl01kq	768	17	diseases	disease	NNS
cord-010027-r0tl01kq	768	18	,	,	,
cord-010027-r0tl01kq	768	19	platforms	platform	NNS
cord-010027-r0tl01kq	768	20	,	,	,
cord-010027-r0tl01kq	768	21	and	and	CC
cord-010027-r0tl01kq	768	22	testing	testing	NN
cord-010027-r0tl01kq	768	23	context	context	NN
cord-010027-r0tl01kq	768	24	(	(	-LRB-
cord-010027-r0tl01kq	768	25	e.g	e.g	FW
cord-010027-r0tl01kq	768	26	,	,	,
cord-010027-r0tl01kq	768	27	.	.	.
cord-010027-r0tl01kq	769	1	Somatic	somatic	JJ
cord-010027-r0tl01kq	769	2	,	,	,
cord-010027-r0tl01kq	769	3	germline	germline	JJ
cord-010027-r0tl01kq	769	4	etc	etc	FW
cord-010027-r0tl01kq	769	5	)	)	-RRB-
cord-010027-r0tl01kq	769	6	)	)	-RRB-
cord-010027-r0tl01kq	769	7	and	and	CC
cord-010027-r0tl01kq	769	8	applicable	applicable	JJ
cord-010027-r0tl01kq	769	9	all	all	DT
cord-010027-r0tl01kq	769	10	users	user	NNS
cord-010027-r0tl01kq	769	11	.	.	.
cord-010027-r0tl01kq	770	1	Two	two	CD
cord-010027-r0tl01kq	770	2	pilot	pilot	NN
cord-010027-r0tl01kq	770	3	EQAs	eqa	NNS
cord-010027-r0tl01kq	770	4	have	have	VBP
cord-010027-r0tl01kq	770	5	been	be	VBN
cord-010027-r0tl01kq	770	6	run	run	VBN
cord-010027-r0tl01kq	770	7	and	and	CC
cord-010027-r0tl01kq	770	8	157	157	CD
cord-010027-r0tl01kq	770	9	labs	lab	NNS
cord-010027-r0tl01kq	770	10	from	from	IN
cord-010027-r0tl01kq	770	11	32	32	CD
cord-010027-r0tl01kq	770	12	countries	country	NNS
cord-010027-r0tl01kq	770	13	participated	participate	VBD
cord-010027-r0tl01kq	770	14	.	.	.
cord-010027-r0tl01kq	771	1	These	these	DT
cord-010027-r0tl01kq	771	2	labs	lab	NNS
cord-010027-r0tl01kq	771	3	were	be	VBD
cord-010027-r0tl01kq	771	4	sent	send	VBN
cord-010027-r0tl01kq	771	5	a	a	DT
cord-010027-r0tl01kq	771	6	genomic	genomic	JJ
cord-010027-r0tl01kq	771	7	DNA	dna	NN
cord-010027-r0tl01kq	771	8	sample	sample	NN
cord-010027-r0tl01kq	771	9	and	and	CC
cord-010027-r0tl01kq	771	10	asked	ask	VBD
cord-010027-r0tl01kq	771	11	to	to	TO
cord-010027-r0tl01kq	771	12	sequence	sequence	VB
cord-010027-r0tl01kq	771	13	either	either	CC
cord-010027-r0tl01kq	771	14	their	-PRON-	PRP$
cord-010027-r0tl01kq	771	15	smallest	small	JJS
cord-010027-r0tl01kq	771	16	gene	gene	NN
cord-010027-r0tl01kq	771	17	panel	panel	NN
cord-010027-r0tl01kq	771	18	or	or	CC
cord-010027-r0tl01kq	771	19	largest	large	JJS
cord-010027-r0tl01kq	771	20	single	single	JJ
cord-010027-r0tl01kq	771	21	gene	gene	NN
cord-010027-r0tl01kq	771	22	which	which	WDT
cord-010027-r0tl01kq	771	23	the	the	DT
cord-010027-r0tl01kq	771	24	lab	lab	NN
cord-010027-r0tl01kq	771	25	tested	test	VBN
cord-010027-r0tl01kq	771	26	,	,	,
cord-010027-r0tl01kq	771	27	submit	submit	VBP
cord-010027-r0tl01kq	771	28	technical	technical	JJ
cord-010027-r0tl01kq	771	29	details	detail	NNS
cord-010027-r0tl01kq	771	30	,	,	,
cord-010027-r0tl01kq	771	31	and	and	CC
cord-010027-r0tl01kq	771	32	genotypes	genotype	NNS
cord-010027-r0tl01kq	771	33	at	at	IN
cord-010027-r0tl01kq	771	34	known	know	VBN
cord-010027-r0tl01kq	771	35	SNPs	snp	NNS
cord-010027-r0tl01kq	771	36	.	.	.
cord-010027-r0tl01kq	772	1	The	the	DT
cord-010027-r0tl01kq	772	2	results	result	NNS
cord-010027-r0tl01kq	772	3	were	be	VBD
cord-010027-r0tl01kq	772	4	compared	compare	VBN
cord-010027-r0tl01kq	772	5	against	against	IN
cord-010027-r0tl01kq	772	6	a	a	DT
cord-010027-r0tl01kq	772	7	"	"	``
cord-010027-r0tl01kq	772	8	consensus	consensus	NN
cord-010027-r0tl01kq	772	9	EQA	eqa	NN
cord-010027-r0tl01kq	772	10	genome	genome	NN
cord-010027-r0tl01kq	772	11	"	"	''
cord-010027-r0tl01kq	772	12	established	establish	VBN
cord-010027-r0tl01kq	772	13	by	by	IN
cord-010027-r0tl01kq	772	14	multiple	multiple	JJ
cord-010027-r0tl01kq	772	15	validations	validation	NNS
cord-010027-r0tl01kq	772	16	of	of	IN
cord-010027-r0tl01kq	772	17	the	the	DT
cord-010027-r0tl01kq	772	18	DNA	dna	NN
cord-010027-r0tl01kq	772	19	.	.	.
cord-010027-r0tl01kq	773	1	12187	12187	CD
cord-010027-r0tl01kq	773	2	different	different	JJ
cord-010027-r0tl01kq	773	3	genes	gene	NNS
cord-010027-r0tl01kq	773	4	were	be	VBD
cord-010027-r0tl01kq	773	5	tested	test	VBN
cord-010027-r0tl01kq	773	6	.	.	.
cord-010027-r0tl01kq	774	1	Most	Most	JJS
cord-010027-r0tl01kq	774	2	labs	lab	NNS
cord-010027-r0tl01kq	774	3	are	be	VBP
cord-010027-r0tl01kq	774	4	using	use	VBG
cord-010027-r0tl01kq	774	5	small	small	JJ
cord-010027-r0tl01kq	774	6	panel	panel	NN
cord-010027-r0tl01kq	774	7	of	of	IN
cord-010027-r0tl01kq	774	8	1	1	CD
cord-010027-r0tl01kq	774	9	-	-	SYM
cord-010027-r0tl01kq	774	10	10	10	CD
cord-010027-r0tl01kq	774	11	genes	gene	NNS
cord-010027-r0tl01kq	774	12	.	.	.
cord-010027-r0tl01kq	775	1	60	60	CD
cord-010027-r0tl01kq	775	2	%	%	NN
cord-010027-r0tl01kq	775	3	of	of	IN
cord-010027-r0tl01kq	775	4	all	all	DT
cord-010027-r0tl01kq	775	5	variants	variant	NNS
cord-010027-r0tl01kq	775	6	were	be	VBD
cord-010027-r0tl01kq	775	7	detected	detect	VBN
cord-010027-r0tl01kq	775	8	by	by	IN
cord-010027-r0tl01kq	775	9	every	every	DT
cord-010027-r0tl01kq	775	10	lab	lab	NN
cord-010027-r0tl01kq	775	11	which	which	WDT
cord-010027-r0tl01kq	775	12	tested	test	VBD
cord-010027-r0tl01kq	775	13	for	for	IN
cord-010027-r0tl01kq	775	14	them	-PRON-	PRP
cord-010027-r0tl01kq	775	15	.	.	.
cord-010027-r0tl01kq	776	1	A	a	DT
cord-010027-r0tl01kq	776	2	detailed	detailed	JJ
cord-010027-r0tl01kq	776	3	summary	summary	NN
cord-010027-r0tl01kq	776	4	of	of	IN
cord-010027-r0tl01kq	776	5	the	the	DT
cord-010027-r0tl01kq	776	6	key	key	JJ
cord-010027-r0tl01kq	776	7	findings	finding	NNS
cord-010027-r0tl01kq	776	8	will	will	MD
cord-010027-r0tl01kq	776	9	be	be	VB
cord-010027-r0tl01kq	776	10	presented	present	VBN
cord-010027-r0tl01kq	776	11	.	.	.
cord-010027-r0tl01kq	777	1	Both	both	DT
cord-010027-r0tl01kq	777	2	pilots	pilot	NNS
cord-010027-r0tl01kq	777	3	have	have	VBP
cord-010027-r0tl01kq	777	4	proved	prove	VBN
cord-010027-r0tl01kq	777	5	to	to	TO
cord-010027-r0tl01kq	777	6	be	be	VB
cord-010027-r0tl01kq	777	7	challenging	challenge	VBG
cord-010027-r0tl01kq	777	8	to	to	TO
cord-010027-r0tl01kq	777	9	meet	meet	VB
cord-010027-r0tl01kq	777	10	our	-PRON-	PRP$
cord-010027-r0tl01kq	777	11	objectives	objective	NNS
cord-010027-r0tl01kq	777	12	,	,	,
cord-010027-r0tl01kq	777	13	however	however	RB
cord-010027-r0tl01kq	777	14	the	the	DT
cord-010027-r0tl01kq	777	15	results	result	NNS
cord-010027-r0tl01kq	777	16	have	have	VBP
cord-010027-r0tl01kq	777	17	enabled	enable	VBN
cord-010027-r0tl01kq	777	18	clinical	clinical	JJ
cord-010027-r0tl01kq	777	19	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	777	20	labs	lab	NNS
cord-010027-r0tl01kq	777	21	to	to	TO
cord-010027-r0tl01kq	777	22	start	start	VB
cord-010027-r0tl01kq	777	23	to	to	TO
cord-010027-r0tl01kq	777	24	address	address	VB
cord-010027-r0tl01kq	777	25	the	the	DT
cord-010027-r0tl01kq	777	26	quality	quality	NN
cord-010027-r0tl01kq	777	27	of	of	IN
cord-010027-r0tl01kq	777	28	their	-PRON-	PRP$
cord-010027-r0tl01kq	777	29	NGS	NGS	NNP
cord-010027-r0tl01kq	777	30	testing	testing	NN
cord-010027-r0tl01kq	777	31	.	.	.
cord-010027-r0tl01kq	778	1	Tumours	tumour	NNS
cord-010027-r0tl01kq	778	2	invade	invade	VBP
cord-010027-r0tl01kq	778	3	the	the	DT
cord-010027-r0tl01kq	778	4	vasculature	vasculature	NN
cord-010027-r0tl01kq	778	5	,	,	,
cord-010027-r0tl01kq	778	6	which	which	WDT
cord-010027-r0tl01kq	778	7	transports	transport	VBZ
cord-010027-r0tl01kq	778	8	circulating	circulate	VBG
cord-010027-r0tl01kq	778	9	tumour	tumour	NN
cord-010027-r0tl01kq	778	10	cells	cell	NNS
cord-010027-r0tl01kq	778	11	(	(	-LRB-
cord-010027-r0tl01kq	778	12	CTCs	ctc	NNS
cord-010027-r0tl01kq	778	13	)	)	-RRB-
cord-010027-r0tl01kq	778	14	to	to	IN
cord-010027-r0tl01kq	778	15	distant	distant	JJ
cord-010027-r0tl01kq	778	16	sites	site	NNS
cord-010027-r0tl01kq	778	17	enabling	enable	VBG
cord-010027-r0tl01kq	778	18	growth	growth	NN
cord-010027-r0tl01kq	778	19	of	of	IN
cord-010027-r0tl01kq	778	20	secondary	secondary	JJ
cord-010027-r0tl01kq	778	21	tumours	tumour	NNS
cord-010027-r0tl01kq	778	22	.	.	.
cord-010027-r0tl01kq	779	1	CTCs	ctc	NNS
cord-010027-r0tl01kq	779	2	hold	hold	VBP
cord-010027-r0tl01kq	779	3	the	the	DT
cord-010027-r0tl01kq	779	4	potential	potential	NN
cord-010027-r0tl01kq	779	5	to	to	TO
cord-010027-r0tl01kq	779	6	monitor	monitor	VB
cord-010027-r0tl01kq	779	7	:	:	:
cord-010027-r0tl01kq	779	8	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	779	9	response	response	NN
cord-010027-r0tl01kq	779	10	,	,	,
cord-010027-r0tl01kq	779	11	emergent	emergent	JJ
cord-010027-r0tl01kq	779	12	mutations	mutation	NNS
cord-010027-r0tl01kq	779	13	and	and	CC
cord-010027-r0tl01kq	779	14	act	act	VB
cord-010027-r0tl01kq	779	15	as	as	IN
cord-010027-r0tl01kq	779	16	a	a	DT
cord-010027-r0tl01kq	779	17	screening	screening	NN
cord-010027-r0tl01kq	779	18	tool	tool	NN
cord-010027-r0tl01kq	779	19	for	for	IN
cord-010027-r0tl01kq	779	20	the	the	DT
cord-010027-r0tl01kq	779	21	early	early	JJ
cord-010027-r0tl01kq	779	22	detection	detection	NN
cord-010027-r0tl01kq	779	23	of	of	IN
cord-010027-r0tl01kq	779	24	cancer	cancer	NN
cord-010027-r0tl01kq	779	25	.	.	.
cord-010027-r0tl01kq	780	1	There	there	EX
cord-010027-r0tl01kq	780	2	are	be	VBP
cord-010027-r0tl01kq	780	3	numerous	numerous	JJ
cord-010027-r0tl01kq	780	4	methods	method	NNS
cord-010027-r0tl01kq	780	5	to	to	TO
cord-010027-r0tl01kq	780	6	isolate	isolate	VB
cord-010027-r0tl01kq	780	7	CTCs	ctc	NNS
cord-010027-r0tl01kq	780	8	.	.	.
cord-010027-r0tl01kq	781	1	Once	once	RB
cord-010027-r0tl01kq	781	2	isolated	isolate	VBN
cord-010027-r0tl01kq	781	3	,	,	,
cord-010027-r0tl01kq	781	4	EpCAM	EpCAM	NNP
cord-010027-r0tl01kq	781	5	and/or	and/or	CC
cord-010027-r0tl01kq	781	6	panCK	panck	JJ
cord-010027-r0tl01kq	781	7	positivity	positivity	NN
cord-010027-r0tl01kq	781	8	and	and	CC
cord-010027-r0tl01kq	781	9	CD45	CD45	NNP
cord-010027-r0tl01kq	781	10	negativity	negativity	NN
cord-010027-r0tl01kq	781	11	are	be	VBP
cord-010027-r0tl01kq	781	12	used	use	VBN
cord-010027-r0tl01kq	781	13	to	to	TO
cord-010027-r0tl01kq	781	14	verify	verify	VB
cord-010027-r0tl01kq	781	15	CTC	CTC	NNP
cord-010027-r0tl01kq	781	16	status	status	NN
cord-010027-r0tl01kq	781	17	.	.	.
cord-010027-r0tl01kq	782	1	However	however	RB
cord-010027-r0tl01kq	782	2	,	,	,
cord-010027-r0tl01kq	782	3	due	due	IN
cord-010027-r0tl01kq	782	4	to	to	IN
cord-010027-r0tl01kq	782	5	the	the	DT
cord-010027-r0tl01kq	782	6	metastasis	metastasis	NN
cord-010027-r0tl01kq	782	7	associated	associate	VBN
cord-010027-r0tl01kq	782	8	process	process	NN
cord-010027-r0tl01kq	782	9	of	of	IN
cord-010027-r0tl01kq	782	10	Epithelial	epithelial	NN
cord-010027-r0tl01kq	782	11	-	-	HYPH
cord-010027-r0tl01kq	782	12	Mesenchymal	Mesenchymal	NNP
cord-010027-r0tl01kq	782	13	Transition	Transition	NNP
cord-010027-r0tl01kq	782	14	,	,	,
cord-010027-r0tl01kq	782	15	epithelial	epithelial	JJ
cord-010027-r0tl01kq	782	16	markers	marker	NNS
cord-010027-r0tl01kq	782	17	may	may	MD
cord-010027-r0tl01kq	782	18	be	be	VB
cord-010027-r0tl01kq	782	19	ineffective	ineffective	JJ
cord-010027-r0tl01kq	782	20	at	at	IN
cord-010027-r0tl01kq	782	21	identifying	identify	VBG
cord-010027-r0tl01kq	782	22	all	all	DT
cord-010027-r0tl01kq	782	23	CTCs	ctc	NNS
cord-010027-r0tl01kq	782	24	.	.	.
cord-010027-r0tl01kq	783	1	To	to	TO
cord-010027-r0tl01kq	783	2	overcome	overcome	VB
cord-010027-r0tl01kq	783	3	such	such	JJ
cord-010027-r0tl01kq	783	4	protein	protein	NN
cord-010027-r0tl01kq	783	5	marker	marker	NN
cord-010027-r0tl01kq	783	6	based	base	VBN
cord-010027-r0tl01kq	783	7	limitations	limitation	NNS
cord-010027-r0tl01kq	783	8	,	,	,
cord-010027-r0tl01kq	783	9	we	-PRON-	PRP
cord-010027-r0tl01kq	783	10	have	have	VBP
cord-010027-r0tl01kq	783	11	developed	develop	VBN
cord-010027-r0tl01kq	783	12	a	a	DT
cord-010027-r0tl01kq	783	13	novel	novel	JJ
cord-010027-r0tl01kq	783	14	staining	staining	NN
cord-010027-r0tl01kq	783	15	pipeline	pipeline	NN
cord-010027-r0tl01kq	783	16	(	(	-LRB-
cord-010027-r0tl01kq	783	17	CTC-5	CTC-5	NNP
cord-010027-r0tl01kq	783	18	)	)	-RRB-
cord-010027-r0tl01kq	783	19	that	that	WDT
cord-010027-r0tl01kq	783	20	combines	combine	VBZ
cord-010027-r0tl01kq	783	21	histochemical	histochemical	JJ
cord-010027-r0tl01kq	783	22	staining	staining	NN
cord-010027-r0tl01kq	783	23	(	(	-LRB-
cord-010027-r0tl01kq	783	24	giemsa	giemsa	NNP
cord-010027-r0tl01kq	783	25	)	)	-RRB-
cord-010027-r0tl01kq	783	26	with	with	IN
cord-010027-r0tl01kq	783	27	immunofluorescene	immunofluorescene	JJ
cord-010027-r0tl01kq	783	28	(	(	-LRB-
cord-010027-r0tl01kq	783	29	DAPI	dapi	FW
cord-010027-r0tl01kq	783	30	,	,	,
cord-010027-r0tl01kq	783	31	EpCAM	EpCAM	NNP
cord-010027-r0tl01kq	783	32	/	/	SYM
cord-010027-r0tl01kq	783	33	panCK	panCK	NNP
cord-010027-r0tl01kq	783	34	,	,	,
cord-010027-r0tl01kq	783	35	HER3	HER3	NNP
cord-010027-r0tl01kq	783	36	and	and	CC
cord-010027-r0tl01kq	783	37	CD45	CD45	NNP
cord-010027-r0tl01kq	783	38	)	)	-RRB-
cord-010027-r0tl01kq	783	39	staining	staining	NN
cord-010027-r0tl01kq	783	40	and	and	CC
cord-010027-r0tl01kq	783	41	whole	whole	JJ
cord-010027-r0tl01kq	783	42	slide	slide	NN
cord-010027-r0tl01kq	783	43	imaging	imaging	NN
cord-010027-r0tl01kq	783	44	for	for	IN
cord-010027-r0tl01kq	783	45	robust	robust	JJ
cord-010027-r0tl01kq	783	46	identification	identification	NN
cord-010027-r0tl01kq	783	47	,	,	,
cord-010027-r0tl01kq	783	48	enumeration	enumeration	NN
cord-010027-r0tl01kq	783	49	and	and	CC
cord-010027-r0tl01kq	783	50	characterisation	characterisation	NN
cord-010027-r0tl01kq	783	51	of	of	IN
cord-010027-r0tl01kq	783	52	CTCs	ctc	NNS
cord-010027-r0tl01kq	783	53	from	from	IN
cord-010027-r0tl01kq	783	54	cancer	cancer	NN
cord-010027-r0tl01kq	783	55	patients	patient	NNS
cord-010027-r0tl01kq	783	56	.	.	.
cord-010027-r0tl01kq	784	1	CTCs	ctc	NNS
cord-010027-r0tl01kq	784	2	are	be	VBP
cord-010027-r0tl01kq	784	3	isolated	isolate	VBN
cord-010027-r0tl01kq	784	4	from	from	IN
cord-010027-r0tl01kq	784	5	whole	whole	JJ
cord-010027-r0tl01kq	784	6	blood	blood	NN
cord-010027-r0tl01kq	784	7	using	use	VBG
cord-010027-r0tl01kq	784	8	ScreenCell	ScreenCell	NNP
cord-010027-r0tl01kq	784	9	Cyto	Cyto	NNP
cord-010027-r0tl01kq	784	10	devices	device	NNS
cord-010027-r0tl01kq	784	11	.	.	.
cord-010027-r0tl01kq	785	1	Cyto	Cyto	NNP
cord-010027-r0tl01kq	785	2	devices	device	NNS
cord-010027-r0tl01kq	785	3	are	be	VBP
cord-010027-r0tl01kq	785	4	then	then	RB
cord-010027-r0tl01kq	785	5	slide	slide	NN
cord-010027-r0tl01kq	785	6	mounted	mount	VBN
cord-010027-r0tl01kq	785	7	,	,	,
cord-010027-r0tl01kq	785	8	giemsa	giemsa	NNP
cord-010027-r0tl01kq	785	9	stained	stain	VBN
cord-010027-r0tl01kq	785	10	and	and	CC
cord-010027-r0tl01kq	785	11	digitised	digitised	JJ
cord-010027-r0tl01kq	785	12	.	.	.
cord-010027-r0tl01kq	786	1	Giemsa	Giemsa	NNP
cord-010027-r0tl01kq	786	2	Staining	Staining	NNP
cord-010027-r0tl01kq	786	3	is	be	VBZ
cord-010027-r0tl01kq	786	4	washed	wash	VBN
cord-010027-r0tl01kq	786	5	out	out	RP
cord-010027-r0tl01kq	786	6	and	and	CC
cord-010027-r0tl01kq	786	7	slides	slide	NNS
cord-010027-r0tl01kq	786	8	are	be	VBP
cord-010027-r0tl01kq	786	9	immunofluorescently	immunofluorescently	RB
cord-010027-r0tl01kq	786	10	stained	stain	VBN
cord-010027-r0tl01kq	786	11	for	for	IN
cord-010027-r0tl01kq	786	12	EpCAM	EpCAM	NNP
cord-010027-r0tl01kq	786	13	/	/	SYM
cord-010027-r0tl01kq	786	14	panCK	panCK	NNP
cord-010027-r0tl01kq	786	15	,	,	,
cord-010027-r0tl01kq	787	1	CD45	CD45	NNP
cord-010027-r0tl01kq	787	2	,	,	,
cord-010027-r0tl01kq	787	3	HER3	HER3	NNP
cord-010027-r0tl01kq	787	4	and	and	CC
cord-010027-r0tl01kq	787	5	counter	counter	NN
cord-010027-r0tl01kq	787	6	stained	stain	VBN
cord-010027-r0tl01kq	787	7	with	with	IN
cord-010027-r0tl01kq	787	8	DAPI	DAPI	NNP
cord-010027-r0tl01kq	787	9	.	.	.
cord-010027-r0tl01kq	788	1	Fluorescently	fluorescently	RB
cord-010027-r0tl01kq	788	2	stained	stain	VBN
cord-010027-r0tl01kq	788	3	slides	slide	NNS
cord-010027-r0tl01kq	788	4	are	be	VBP
cord-010027-r0tl01kq	788	5	digitised	digitised	JJ
cord-010027-r0tl01kq	788	6	.	.	.
cord-010027-r0tl01kq	789	1	Giemsa	Giemsa	NNP
cord-010027-r0tl01kq	789	2	stained	stain	VBD
cord-010027-r0tl01kq	789	3	and	and	CC
cord-010027-r0tl01kq	789	4	four	four	CD
cord-010027-r0tl01kq	789	5	colour	colour	NN
cord-010027-r0tl01kq	789	6	immunofluorescent	immunofluorescent	NN
cord-010027-r0tl01kq	789	7	digital	digital	JJ
cord-010027-r0tl01kq	789	8	slides	slide	NNS
cord-010027-r0tl01kq	789	9	are	be	VBP
cord-010027-r0tl01kq	789	10	processed	process	VBN
cord-010027-r0tl01kq	789	11	in	in	IN
cord-010027-r0tl01kq	789	12	silico	silico	NN
cord-010027-r0tl01kq	789	13	generating	generate	VBG
cord-010027-r0tl01kq	789	14	a	a	DT
cord-010027-r0tl01kq	789	15	single	single	JJ
cord-010027-r0tl01kq	789	16	z	z	NN
cord-010027-r0tl01kq	789	17	-	-	HYPH
cord-010027-r0tl01kq	789	18	stacked	stack	VBN
cord-010027-r0tl01kq	789	19	digital	digital	JJ
cord-010027-r0tl01kq	789	20	slide	slide	NN
cord-010027-r0tl01kq	789	21	for	for	IN
cord-010027-r0tl01kq	789	22	pathological	pathological	JJ
cord-010027-r0tl01kq	789	23	assessment	assessment	NN
cord-010027-r0tl01kq	789	24	.	.	.
cord-010027-r0tl01kq	790	1	The	the	DT
cord-010027-r0tl01kq	790	2	CTC-5	CTC-5	NNP
cord-010027-r0tl01kq	790	3	staining	staining	NN
cord-010027-r0tl01kq	790	4	pipeline	pipeline	NN
cord-010027-r0tl01kq	790	5	has	have	VBZ
cord-010027-r0tl01kq	790	6	been	be	VBN
cord-010027-r0tl01kq	790	7	experimentally	experimentally	RB
cord-010027-r0tl01kq	790	8	validated	validate	VBN
cord-010027-r0tl01kq	790	9	via	via	IN
cord-010027-r0tl01kq	790	10	CTC	CTC	NNP
cord-010027-r0tl01kq	790	11	characterisation	characterisation	NN
cord-010027-r0tl01kq	790	12	of	of	IN
cord-010027-r0tl01kq	790	13	peripheral	peripheral	JJ
cord-010027-r0tl01kq	790	14	blood	blood	NN
cord-010027-r0tl01kq	790	15	from	from	IN
cord-010027-r0tl01kq	790	16	Lung	Lung	NNP
cord-010027-r0tl01kq	790	17	,	,	,
cord-010027-r0tl01kq	790	18	Breast	breast	NN
cord-010027-r0tl01kq	790	19	and	and	CC
cord-010027-r0tl01kq	790	20	Ovarian	ovarian	JJ
cord-010027-r0tl01kq	790	21	cancer	cancer	NN
cord-010027-r0tl01kq	790	22	patients	patient	NNS
cord-010027-r0tl01kq	790	23	,	,	,
cord-010027-r0tl01kq	790	24	with	with	IN
cord-010027-r0tl01kq	790	25	respect	respect	NN
cord-010027-r0tl01kq	790	26	to	to	IN
cord-010027-r0tl01kq	790	27	healthy	healthy	JJ
cord-010027-r0tl01kq	790	28	donor	donor	NN
cord-010027-r0tl01kq	790	29	and	and	CC
cord-010027-r0tl01kq	790	30	spiked	spike	VBN
cord-010027-r0tl01kq	790	31	-	-	HYPH
cord-010027-r0tl01kq	790	32	in	in	RP
cord-010027-r0tl01kq	790	33	controls	control	NNS
cord-010027-r0tl01kq	790	34	.	.	.
cord-010027-r0tl01kq	791	1	The	the	DT
cord-010027-r0tl01kq	791	2	CTC-5	CTC-5	NNP
cord-010027-r0tl01kq	791	3	pipeline	pipeline	NN
cord-010027-r0tl01kq	791	4	overcomes	overcome	VBZ
cord-010027-r0tl01kq	791	5	recognised	recognise	VBN
cord-010027-r0tl01kq	791	6	weaknesses	weakness	NNS
cord-010027-r0tl01kq	791	7	in	in	IN
cord-010027-r0tl01kq	791	8	CTC	CTC	NNP
cord-010027-r0tl01kq	791	9	characterisation	characterisation	NN
cord-010027-r0tl01kq	791	10	.	.	.
cord-010027-r0tl01kq	792	1	Histochemical	Histochemical	NNP
cord-010027-r0tl01kq	792	2	staining	staining	NN
cord-010027-r0tl01kq	792	3	is	be	VBZ
cord-010027-r0tl01kq	792	4	added	add	VBN
cord-010027-r0tl01kq	792	5	to	to	IN
cord-010027-r0tl01kq	792	6	the	the	DT
cord-010027-r0tl01kq	792	7	current	current	JJ
cord-010027-r0tl01kq	792	8	gold	gold	NN
cord-010027-r0tl01kq	792	9	standard	standard	NN
cord-010027-r0tl01kq	792	10	of	of	IN
cord-010027-r0tl01kq	792	11	EpCAM	EpCAM	NNP
cord-010027-r0tl01kq	792	12	/	/	SYM
cord-010027-r0tl01kq	792	13	panCK	panCK	NNP
cord-010027-r0tl01kq	792	14	and	and	CC
cord-010027-r0tl01kq	792	15	CD45	CD45	NNP
cord-010027-r0tl01kq	792	16	staining	staining	NN
cord-010027-r0tl01kq	792	17	,	,	,
cord-010027-r0tl01kq	792	18	while	while	IN
cord-010027-r0tl01kq	792	19	also	also	RB
cord-010027-r0tl01kq	792	20	preserving	preserve	VBG
cord-010027-r0tl01kq	792	21	a	a	DT
cord-010027-r0tl01kq	792	22	fluorescent	fluorescent	JJ
cord-010027-r0tl01kq	792	23	channel	channel	NN
cord-010027-r0tl01kq	792	24	for	for	IN
cord-010027-r0tl01kq	792	25	assessment	assessment	NN
cord-010027-r0tl01kq	792	26	of	of	IN
cord-010027-r0tl01kq	792	27	biomarker	biomarker	NN
cord-010027-r0tl01kq	792	28	status	status	NN
cord-010027-r0tl01kq	792	29	(	(	-LRB-
cord-010027-r0tl01kq	792	30	e.g.	e.g.	IN
cord-010027-r0tl01kq	792	31	HER3	HER3	NNP
cord-010027-r0tl01kq	792	32	,	,	,
cord-010027-r0tl01kq	792	33	apoptosis	apoptosis	NN
cord-010027-r0tl01kq	792	34	or	or	CC
cord-010027-r0tl01kq	792	35	platelet	platelet	NN
cord-010027-r0tl01kq	792	36	cloaking	cloaking	NN
cord-010027-r0tl01kq	792	37	)	)	-RRB-
cord-010027-r0tl01kq	792	38	.	.	.
cord-010027-r0tl01kq	793	1	Such	such	JJ
cord-010027-r0tl01kq	793	2	advancements	advancement	NNS
cord-010027-r0tl01kq	793	3	enable	enable	VBP
cord-010027-r0tl01kq	793	4	robust	robust	JJ
cord-010027-r0tl01kq	793	5	pathological	pathological	JJ
cord-010027-r0tl01kq	793	6	assessment	assessment	NN
cord-010027-r0tl01kq	793	7	of	of	IN
cord-010027-r0tl01kq	793	8	CTCs	ctc	NNS
cord-010027-r0tl01kq	793	9	in	in	IN
cord-010027-r0tl01kq	793	10	the	the	DT
cord-010027-r0tl01kq	793	11	clinic	clinic	NN
cord-010027-r0tl01kq	793	12	.	.	.
cord-010027-r0tl01kq	794	1	Thorough	thorough	JJ
cord-010027-r0tl01kq	794	2	interrogation	interrogation	NN
cord-010027-r0tl01kq	794	3	of	of	IN
cord-010027-r0tl01kq	794	4	diseased	diseased	JJ
cord-010027-r0tl01kq	794	5	tissue	tissue	NN
cord-010027-r0tl01kq	794	6	requires	require	VBZ
cord-010027-r0tl01kq	794	7	the	the	DT
cord-010027-r0tl01kq	794	8	use	use	NN
cord-010027-r0tl01kq	794	9	of	of	IN
cord-010027-r0tl01kq	794	10	multiple	multiple	JJ
cord-010027-r0tl01kq	794	11	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	794	12	in	in	IN
cord-010027-r0tl01kq	794	13	order	order	NN
cord-010027-r0tl01kq	794	14	to	to	TO
cord-010027-r0tl01kq	794	15	investigate	investigate	VB
cord-010027-r0tl01kq	794	16	biological	biological	JJ
cord-010027-r0tl01kq	794	17	pathways	pathway	NNS
cord-010027-r0tl01kq	794	18	.	.	.
cord-010027-r0tl01kq	795	1	Unless	unless	IN
cord-010027-r0tl01kq	795	2	fluorescent	fluorescent	JJ
cord-010027-r0tl01kq	795	3	technology	technology	NN
cord-010027-r0tl01kq	795	4	is	be	VBZ
cord-010027-r0tl01kq	795	5	used	use	VBN
cord-010027-r0tl01kq	795	6	,	,	,
cord-010027-r0tl01kq	795	7	multiple	multiple	JJ
cord-010027-r0tl01kq	795	8	sections	section	NNS
cord-010027-r0tl01kq	795	9	are	be	VBP
cord-010027-r0tl01kq	795	10	required	require	VBN
cord-010027-r0tl01kq	795	11	from	from	IN
cord-010027-r0tl01kq	795	12	each	each	DT
cord-010027-r0tl01kq	795	13	tissue	tissue	NN
cord-010027-r0tl01kq	795	14	block	block	NN
cord-010027-r0tl01kq	795	15	as	as	IN
cord-010027-r0tl01kq	795	16	each	each	DT
cord-010027-r0tl01kq	795	17	section	section	NN
cord-010027-r0tl01kq	795	18	can	can	MD
cord-010027-r0tl01kq	795	19	only	only	RB
cord-010027-r0tl01kq	795	20	be	be	VB
cord-010027-r0tl01kq	795	21	tested	test	VBN
cord-010027-r0tl01kq	795	22	for	for	IN
cord-010027-r0tl01kq	795	23	a	a	DT
cord-010027-r0tl01kq	795	24	limited	limited	JJ
cord-010027-r0tl01kq	795	25	number	number	NN
cord-010027-r0tl01kq	795	26	of	of	IN
cord-010027-r0tl01kq	795	27	markers	marker	NNS
cord-010027-r0tl01kq	795	28	.	.	.
cord-010027-r0tl01kq	796	1	Histogenic	Histogenic	NNP
cord-010027-r0tl01kq	796	2	Molecular	Molecular	NNP
cord-010027-r0tl01kq	796	3	Mapping	Mapping	NNP
cord-010027-r0tl01kq	796	4	(	(	-LRB-
cord-010027-r0tl01kq	796	5	HMM	HMM	NNP
cord-010027-r0tl01kq	796	6	)	)	-RRB-
cord-010027-r0tl01kq	796	7	is	be	VBZ
cord-010027-r0tl01kq	796	8	a	a	DT
cord-010027-r0tl01kq	796	9	technique	technique	NN
cord-010027-r0tl01kq	796	10	which	which	WDT
cord-010027-r0tl01kq	796	11	used	use	VBD
cord-010027-r0tl01kq	796	12	digitized	digitized	JJ
cord-010027-r0tl01kq	796	13	images	image	NNS
cord-010027-r0tl01kq	796	14	to	to	TO
cord-010027-r0tl01kq	796	15	evaluate	evaluate	VB
cord-010027-r0tl01kq	796	16	multiple	multiple	JJ
cord-010027-r0tl01kq	796	17	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	796	18	.	.	.
cord-010027-r0tl01kq	797	1	Although	although	IN
cord-010027-r0tl01kq	797	2	each	each	DT
cord-010027-r0tl01kq	797	3	section	section	NN
cord-010027-r0tl01kq	797	4	cut	cut	VBN
cord-010027-r0tl01kq	797	5	from	from	IN
cord-010027-r0tl01kq	797	6	a	a	DT
cord-010027-r0tl01kq	797	7	block	block	NN
cord-010027-r0tl01kq	797	8	is	be	VBZ
cord-010027-r0tl01kq	797	9	slightly	slightly	RB
cord-010027-r0tl01kq	797	10	different	different	JJ
cord-010027-r0tl01kq	797	11	from	from	IN
cord-010027-r0tl01kq	797	12	the	the	DT
cord-010027-r0tl01kq	797	13	immediately	immediately	RB
cord-010027-r0tl01kq	797	14	preceding	precede	VBG
cord-010027-r0tl01kq	797	15	section	section	NN
cord-010027-r0tl01kq	797	16	,	,	,
cord-010027-r0tl01kq	797	17	the	the	DT
cord-010027-r0tl01kq	797	18	similarity	similarity	NN
cord-010027-r0tl01kq	797	19	is	be	VBZ
cord-010027-r0tl01kq	797	20	sufficient	sufficient	JJ
cord-010027-r0tl01kq	797	21	to	to	TO
cord-010027-r0tl01kq	797	22	allow	allow	VB
cord-010027-r0tl01kq	797	23	non	non	JJ
cord-010027-r0tl01kq	797	24	-	-	JJ
cord-010027-r0tl01kq	797	25	linear	linear	JJ
cord-010027-r0tl01kq	797	26	registration	registration	NN
cord-010027-r0tl01kq	797	27	of	of	IN
cord-010027-r0tl01kq	797	28	images	image	NNS
cord-010027-r0tl01kq	797	29	of	of	IN
cord-010027-r0tl01kq	797	30	successive	successive	JJ
cord-010027-r0tl01kq	797	31	sections	section	NNS
cord-010027-r0tl01kq	797	32	.	.	.
cord-010027-r0tl01kq	798	1	If	if	IN
cord-010027-r0tl01kq	798	2	the	the	DT
cord-010027-r0tl01kq	798	3	order	order	NN
cord-010027-r0tl01kq	798	4	is	be	VBZ
cord-010027-r0tl01kq	798	5	known	know	VBN
cord-010027-r0tl01kq	798	6	,	,	,
cord-010027-r0tl01kq	798	7	multiple	multiple	JJ
cord-010027-r0tl01kq	798	8	sections	section	NNS
cord-010027-r0tl01kq	798	9	can	can	MD
cord-010027-r0tl01kq	798	10	be	be	VB
cord-010027-r0tl01kq	798	11	mapped	map	VBN
cord-010027-r0tl01kq	798	12	onto	onto	IN
cord-010027-r0tl01kq	798	13	each	each	DT
cord-010027-r0tl01kq	798	14	other	other	JJ
cord-010027-r0tl01kq	798	15	by	by	IN
cord-010027-r0tl01kq	798	16	registering	register	VBG
cord-010027-r0tl01kq	798	17	each	each	DT
cord-010027-r0tl01kq	798	18	with	with	IN
cord-010027-r0tl01kq	798	19	the	the	DT
cord-010027-r0tl01kq	798	20	immediately	immediately	RB
cord-010027-r0tl01kq	798	21	preceding	precede	VBG
cord-010027-r0tl01kq	798	22	section	section	NN
cord-010027-r0tl01kq	798	23	.	.	.
cord-010027-r0tl01kq	799	1	This	this	DT
cord-010027-r0tl01kq	799	2	allows	allow	VBZ
cord-010027-r0tl01kq	799	3	several	several	JJ
cord-010027-r0tl01kq	799	4	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	799	5	to	to	TO
cord-010027-r0tl01kq	799	6	be	be	VB
cord-010027-r0tl01kq	799	7	mapped	map	VBN
cord-010027-r0tl01kq	799	8	into	into	IN
cord-010027-r0tl01kq	799	9	a	a	DT
cord-010027-r0tl01kq	799	10	single	single	JJ
cord-010027-r0tl01kq	799	11	"	"	``
cord-010027-r0tl01kq	799	12	composite	composite	JJ
cord-010027-r0tl01kq	799	13	"	"	''
cord-010027-r0tl01kq	799	14	section	section	NN
cord-010027-r0tl01kq	799	15	thereby	thereby	RB
cord-010027-r0tl01kq	799	16	giving	give	VBG
cord-010027-r0tl01kq	799	17	a	a	DT
cord-010027-r0tl01kq	799	18	representation	representation	NN
cord-010027-r0tl01kq	799	19	of	of	IN
cord-010027-r0tl01kq	799	20	the	the	DT
cord-010027-r0tl01kq	799	21	pathways	pathway	NNS
cord-010027-r0tl01kq	799	22	activated	activate	VBN
cord-010027-r0tl01kq	799	23	/	/	SYM
cord-010027-r0tl01kq	799	24	expressed	express	VBD
cord-010027-r0tl01kq	799	25	in	in	IN
cord-010027-r0tl01kq	799	26	the	the	DT
cord-010027-r0tl01kq	799	27	tissue	tissue	NN
cord-010027-r0tl01kq	799	28	.	.	.
cord-010027-r0tl01kq	800	1	We	-PRON-	PRP
cord-010027-r0tl01kq	800	2	used	use	VBD
cord-010027-r0tl01kq	800	3	HMM	HMM	NNP
cord-010027-r0tl01kq	800	4	to	to	TO
cord-010027-r0tl01kq	800	5	investigate	investigate	VB
cord-010027-r0tl01kq	800	6	the	the	DT
cord-010027-r0tl01kq	800	7	mismatch	mismatch	NN
cord-010027-r0tl01kq	800	8	repair	repair	NN
cord-010027-r0tl01kq	800	9	pathway	pathway	NN
cord-010027-r0tl01kq	800	10	in	in	IN
cord-010027-r0tl01kq	800	11	colorectal	colorectal	JJ
cord-010027-r0tl01kq	800	12	cancer	cancer	NN
cord-010027-r0tl01kq	800	13	.	.	.
cord-010027-r0tl01kq	801	1	Sequential	sequential	JJ
cord-010027-r0tl01kq	801	2	tissue	tissue	NN
cord-010027-r0tl01kq	801	3	sections	section	NNS
cord-010027-r0tl01kq	801	4	were	be	VBD
cord-010027-r0tl01kq	801	5	stained	stain	VBN
cord-010027-r0tl01kq	801	6	for	for	IN
cord-010027-r0tl01kq	801	7	MLH1	MLH1	NNP
cord-010027-r0tl01kq	801	8	,	,	,
cord-010027-r0tl01kq	801	9	PMS2	PMS2	NNP
cord-010027-r0tl01kq	801	10	,	,	,
cord-010027-r0tl01kq	801	11	MSH2	MSH2	NNP
cord-010027-r0tl01kq	801	12	and	and	CC
cord-010027-r0tl01kq	801	13	MSH6	MSH6	NNPS
cord-010027-r0tl01kq	801	14	and	and	CC
cord-010027-r0tl01kq	801	15	then	then	RB
cord-010027-r0tl01kq	801	16	scanned	scan	VBD
cord-010027-r0tl01kq	801	17	.	.	.
cord-010027-r0tl01kq	802	1	Bespoke	bespoke	JJ
cord-010027-r0tl01kq	802	2	computational	computational	JJ
cord-010027-r0tl01kq	802	3	algorithms	algorithm	NNS
cord-010027-r0tl01kq	802	4	were	be	VBD
cord-010027-r0tl01kq	802	5	used	use	VBN
cord-010027-r0tl01kq	802	6	for	for	IN
cord-010027-r0tl01kq	802	7	image	image	NN
cord-010027-r0tl01kq	802	8	registration	registration	NN
cord-010027-r0tl01kq	802	9	and	and	CC
cord-010027-r0tl01kq	802	10	composite	composite	JJ
cord-010027-r0tl01kq	802	11	images	image	NNS
cord-010027-r0tl01kq	802	12	were	be	VBD
cord-010027-r0tl01kq	802	13	binned	bin	VBN
cord-010027-r0tl01kq	802	14	as	as	IN
cord-010027-r0tl01kq	802	15	either	either	DT
cord-010027-r0tl01kq	802	16	"	"	``
cord-010027-r0tl01kq	802	17	mismatch	mismatch	NN
cord-010027-r0tl01kq	802	18	repair	repair	NN
cord-010027-r0tl01kq	802	19	proficient	proficient	JJ
cord-010027-r0tl01kq	802	20	"	"	''
cord-010027-r0tl01kq	802	21	or	or	CC
cord-010027-r0tl01kq	802	22	"	"	``
cord-010027-r0tl01kq	802	23	mismatch	mismatch	NN
cord-010027-r0tl01kq	802	24	repair	repair	NN
cord-010027-r0tl01kq	802	25	deficient	deficient	JJ
cord-010027-r0tl01kq	802	26	"	"	''
cord-010027-r0tl01kq	802	27	.	.	.
cord-010027-r0tl01kq	803	1	Validation	validation	NN
cord-010027-r0tl01kq	803	2	of	of	IN
cord-010027-r0tl01kq	803	3	each	each	DT
cord-010027-r0tl01kq	803	4	category	category	NN
cord-010027-r0tl01kq	803	5	could	could	MD
cord-010027-r0tl01kq	803	6	be	be	VB
cord-010027-r0tl01kq	803	7	obtained	obtain	VBN
cord-010027-r0tl01kq	803	8	by	by	IN
cord-010027-r0tl01kq	803	9	quantification	quantification	NN
cord-010027-r0tl01kq	803	10	of	of	IN
cord-010027-r0tl01kq	803	11	pixels	pixel	NNS
cord-010027-r0tl01kq	803	12	in	in	IN
cord-010027-r0tl01kq	803	13	binarized	binarize	VBN
cord-010027-r0tl01kq	803	14	images	image	NNS
cord-010027-r0tl01kq	803	15	or	or	CC
cord-010027-r0tl01kq	803	16	pixel	pixel	NN
cord-010027-r0tl01kq	803	17	distribution	distribution	NN
cord-010027-r0tl01kq	803	18	using	use	VBG
cord-010027-r0tl01kq	803	19	stereology	stereology	NN
cord-010027-r0tl01kq	803	20	.	.	.
cord-010027-r0tl01kq	804	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	804	2	data	datum	NNS
cord-010027-r0tl01kq	804	3	show	show	VBP
cord-010027-r0tl01kq	804	4	that	that	IN
cord-010027-r0tl01kq	804	5	HMM	HMM	NNP
cord-010027-r0tl01kq	804	6	can	can	MD
cord-010027-r0tl01kq	804	7	be	be	VB
cord-010027-r0tl01kq	804	8	used	use	VBN
cord-010027-r0tl01kq	804	9	for	for	IN
cord-010027-r0tl01kq	804	10	interrogating	interrogate	VBG
cord-010027-r0tl01kq	804	11	biological	biological	JJ
cord-010027-r0tl01kq	804	12	pathways	pathway	NNS
cord-010027-r0tl01kq	804	13	in	in	IN
cord-010027-r0tl01kq	804	14	tissue	tissue	NN
cord-010027-r0tl01kq	804	15	sections	section	NNS
cord-010027-r0tl01kq	804	16	and	and	CC
cord-010027-r0tl01kq	804	17	,	,	,
cord-010027-r0tl01kq	804	18	ultimately	ultimately	RB
cord-010027-r0tl01kq	804	19	,	,	,
cord-010027-r0tl01kq	804	20	automated	automate	VBN
cord-010027-r0tl01kq	804	21	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	804	22	of	of	IN
cord-010027-r0tl01kq	804	23	disease	disease	NN
cord-010027-r0tl01kq	804	24	states	state	NNS
cord-010027-r0tl01kq	804	25	.	.	.
cord-010027-r0tl01kq	805	1	Personalising	Personalising	NNP
cord-010027-r0tl01kq	806	1	Whilst	whilst	IN
cord-010027-r0tl01kq	807	1	pre	pre	JJ
cord-010027-r0tl01kq	807	2	-	-	JJ
cord-010027-r0tl01kq	807	3	operative	operative	JJ
cord-010027-r0tl01kq	807	4	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	807	5	is	be	VBZ
cord-010027-r0tl01kq	807	6	the	the	DT
cord-010027-r0tl01kq	807	7	standard	standard	NN
cord-010027-r0tl01kq	807	8	of	of	IN
cord-010027-r0tl01kq	807	9	care	care	NN
cord-010027-r0tl01kq	807	10	in	in	IN
cord-010027-r0tl01kq	807	11	locally	locally	RB
cord-010027-r0tl01kq	807	12	advanced	advanced	JJ
cord-010027-r0tl01kq	807	13	rectal	rectal	JJ
cord-010027-r0tl01kq	807	14	cancer	cancer	NN
cord-010027-r0tl01kq	807	15	(	(	-LRB-
cord-010027-r0tl01kq	807	16	LARC	LARC	NNP
cord-010027-r0tl01kq	807	17	)	)	-RRB-
cord-010027-r0tl01kq	807	18	,	,	,
cord-010027-r0tl01kq	807	19	only	only	RB
cord-010027-r0tl01kq	807	20	half	half	NN
cord-010027-r0tl01kq	807	21	of	of	IN
cord-010027-r0tl01kq	807	22	patients	patient	NNS
cord-010027-r0tl01kq	807	23	respond	respond	VBP
cord-010027-r0tl01kq	807	24	.	.	.
cord-010027-r0tl01kq	808	1	Individualised	individualised	JJ
cord-010027-r0tl01kq	808	2	treatment	treatment	NN
cord-010027-r0tl01kq	808	3	based	base	VBN
cord-010027-r0tl01kq	808	4	on	on	IN
cord-010027-r0tl01kq	808	5	a	a	DT
cord-010027-r0tl01kq	808	6	predictive	predictive	JJ
cord-010027-r0tl01kq	808	7	test	test	NN
cord-010027-r0tl01kq	808	8	could	could	MD
cord-010027-r0tl01kq	808	9	avoid	avoid	VB
cord-010027-r0tl01kq	808	10	unnecessary	unnecessary	JJ
cord-010027-r0tl01kq	808	11	radiation	radiation	NN
cord-010027-r0tl01kq	808	12	exposure	exposure	NN
cord-010027-r0tl01kq	808	13	in	in	IN
cord-010027-r0tl01kq	808	14	poor	poor	JJ
cord-010027-r0tl01kq	808	15	responders	responder	NNS
cord-010027-r0tl01kq	808	16	.	.	.
cord-010027-r0tl01kq	809	1	Macrophages	macrophage	NNS
cord-010027-r0tl01kq	809	2	in	in	IN
cord-010027-r0tl01kq	809	3	the	the	DT
cord-010027-r0tl01kq	809	4	tumour	tumour	NN
cord-010027-r0tl01kq	809	5	microenvironment	microenvironment	NN
cord-010027-r0tl01kq	809	6	with	with	IN
cord-010027-r0tl01kq	809	7	tumoricidal	tumoricidal	JJ
cord-010027-r0tl01kq	809	8	M1	M1	NNP
cord-010027-r0tl01kq	809	9	and	and	CC
cord-010027-r0tl01kq	809	10	tumour	tumour	NN
cord-010027-r0tl01kq	809	11	protective	protective	JJ
cord-010027-r0tl01kq	809	12	M2	m2	JJ
cord-010027-r0tl01kq	809	13	phenotypes	phenotype	NNS
cord-010027-r0tl01kq	809	14	could	could	MD
cord-010027-r0tl01kq	809	15	be	be	VB
cord-010027-r0tl01kq	809	16	modulating	modulate	VBG
cord-010027-r0tl01kq	809	17	this	this	DT
cord-010027-r0tl01kq	809	18	response	response	NN
cord-010027-r0tl01kq	809	19	.	.	.
cord-010027-r0tl01kq	810	1	This	this	DT
cord-010027-r0tl01kq	810	2	study	study	NN
cord-010027-r0tl01kq	810	3	investigated	investigate	VBD
cord-010027-r0tl01kq	810	4	the	the	DT
cord-010027-r0tl01kq	810	5	possible	possible	JJ
cord-010027-r0tl01kq	810	6	predictive	predictive	JJ
cord-010027-r0tl01kq	810	7	value	value	NN
cord-010027-r0tl01kq	810	8	of	of	IN
cord-010027-r0tl01kq	810	9	M1	M1	NNP
cord-010027-r0tl01kq	810	10	and	and	CC
cord-010027-r0tl01kq	810	11	M2	M2	NNP
cord-010027-r0tl01kq	810	12	subpopulations	subpopulation	NNS
cord-010027-r0tl01kq	810	13	in	in	IN
cord-010027-r0tl01kq	810	14	identifying	identify	VBG
cord-010027-r0tl01kq	810	15	the	the	DT
cord-010027-r0tl01kq	810	16	response	response	NN
cord-010027-r0tl01kq	810	17	to	to	IN
cord-010027-r0tl01kq	810	18	short	short	JJ
cord-010027-r0tl01kq	810	19	-	-	HYPH
cord-010027-r0tl01kq	810	20	course	course	NN
cord-010027-r0tl01kq	810	21	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	810	22	(	(	-LRB-
cord-010027-r0tl01kq	810	23	SCRT	SCRT	NNP
cord-010027-r0tl01kq	810	24	)	)	-RRB-
cord-010027-r0tl01kq	810	25	.	.	.
cord-010027-r0tl01kq	811	1	Pre	pre	JJ
cord-010027-r0tl01kq	811	2	-	-	JJ
cord-010027-r0tl01kq	811	3	treatment	treatment	JJ
cord-010027-r0tl01kq	811	4	biopsies	biopsy	NNS
cord-010027-r0tl01kq	811	5	and	and	CC
cord-010027-r0tl01kq	811	6	post	post	JJ
cord-010027-r0tl01kq	811	7	-	-	JJ
cord-010027-r0tl01kq	811	8	treatment	treatment	JJ
cord-010027-r0tl01kq	811	9	resection	resection	NN
cord-010027-r0tl01kq	811	10	samples	sample	NNS
cord-010027-r0tl01kq	811	11	were	be	VBD
cord-010027-r0tl01kq	811	12	taken	take	VBN
cord-010027-r0tl01kq	811	13	from	from	IN
cord-010027-r0tl01kq	811	14	29	29	CD
cord-010027-r0tl01kq	811	15	patients	patient	NNS
cord-010027-r0tl01kq	811	16	with	with	IN
cord-010027-r0tl01kq	811	17	LARC	LARC	NNP
cord-010027-r0tl01kq	811	18	given	give	VBN
cord-010027-r0tl01kq	811	19	SCRT	SCRT	NNP
cord-010027-r0tl01kq	811	20	.	.	.
cord-010027-r0tl01kq	812	1	Dual	dual	JJ
cord-010027-r0tl01kq	812	2	-	-	HYPH
cord-010027-r0tl01kq	812	3	staining	stain	VBG
cord-010027-r0tl01kq	812	4	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	812	5	was	be	VBD
cord-010027-r0tl01kq	812	6	performed	perform	VBN
cord-010027-r0tl01kq	812	7	with	with	IN
cord-010027-r0tl01kq	812	8	CD68	CD68	NNP
cord-010027-r0tl01kq	812	9	,	,	,
cord-010027-r0tl01kq	812	10	HLA	HLA	NNP
cord-010027-r0tl01kq	812	11	-	-	HYPH
cord-010027-r0tl01kq	812	12	DR	DR	NNP
cord-010027-r0tl01kq	812	13	(	(	-LRB-
cord-010027-r0tl01kq	812	14	M1	M1	NNP
cord-010027-r0tl01kq	812	15	marker	marker	NN
cord-010027-r0tl01kq	812	16	)	)	-RRB-
cord-010027-r0tl01kq	812	17	,	,	,
cord-010027-r0tl01kq	812	18	and	and	CC
cord-010027-r0tl01kq	812	19	CD163	CD163	NNP
cord-010027-r0tl01kq	812	20	(	(	-LRB-
cord-010027-r0tl01kq	812	21	M2	m2	JJ
cord-010027-r0tl01kq	812	22	marker	marker	NN
cord-010027-r0tl01kq	812	23	)	)	-RRB-
cord-010027-r0tl01kq	812	24	.	.	.
cord-010027-r0tl01kq	813	1	Samples	sample	NNS
cord-010027-r0tl01kq	813	2	were	be	VBD
cord-010027-r0tl01kq	813	3	scored	score	VBN
cord-010027-r0tl01kq	813	4	for	for	IN
cord-010027-r0tl01kq	813	5	hot	hot	JJ
cord-010027-r0tl01kq	813	6	-	-	HYPH
cord-010027-r0tl01kq	813	7	and	and	CC
cord-010027-r0tl01kq	813	8	-	-	HYPH
cord-010027-r0tl01kq	813	9	random	random	JJ
cord-010027-r0tl01kq	813	10	spots	spot	NNS
cord-010027-r0tl01kq	813	11	by	by	IN
cord-010027-r0tl01kq	813	12	Nuance	nuance	NN
cord-010027-r0tl01kq	813	13	software	software	NN
cord-010027-r0tl01kq	813	14	(	(	-LRB-
cord-010027-r0tl01kq	813	15	version	version	NN
cord-010027-r0tl01kq	813	16	3.0.2	3.0.2	CD
cord-010027-r0tl01kq	813	17	)	)	-RRB-
cord-010027-r0tl01kq	813	18	and	and	CC
cord-010027-r0tl01kq	813	19	compared	compare	VBN
cord-010027-r0tl01kq	813	20	with	with	IN
cord-010027-r0tl01kq	813	21	tumour	tumour	NN
cord-010027-r0tl01kq	813	22	response	response	NN
cord-010027-r0tl01kq	813	23	measured	measure	VBN
cord-010027-r0tl01kq	813	24	by	by	IN
cord-010027-r0tl01kq	813	25	reduction	reduction	NN
cord-010027-r0tl01kq	813	26	in	in	IN
cord-010027-r0tl01kq	813	27	tumour	tumour	NN
cord-010027-r0tl01kq	813	28	-	-	HYPH
cord-010027-r0tl01kq	813	29	cell	cell	NN
cord-010027-r0tl01kq	813	30	density	density	NN
cord-010027-r0tl01kq	813	31	.	.	.
cord-010027-r0tl01kq	814	1	The	the	DT
cord-010027-r0tl01kq	814	2	work	work	NN
cord-010027-r0tl01kq	814	3	was	be	VBD
cord-010027-r0tl01kq	814	4	partly	partly	RB
cord-010027-r0tl01kq	814	5	funded	fund	VBN
cord-010027-r0tl01kq	814	6	by	by	IN
cord-010027-r0tl01kq	814	7	a	a	DT
cord-010027-r0tl01kq	814	8	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	814	9	Career	Career	NNP
cord-010027-r0tl01kq	814	10	Development	Development	NNP
cord-010027-r0tl01kq	814	11	Fellowship	Fellowship	NNP
cord-010027-r0tl01kq	814	12	.	.	.
cord-010027-r0tl01kq	815	1	Samples	sample	NNS
cord-010027-r0tl01kq	815	2	showing	show	VBG
cord-010027-r0tl01kq	815	3	a	a	DT
cord-010027-r0tl01kq	815	4	low	low	JJ
cord-010027-r0tl01kq	815	5	score	score	NN
cord-010027-r0tl01kq	815	6	for	for	IN
cord-010027-r0tl01kq	815	7	HLA	HLA	NNP
cord-010027-r0tl01kq	815	8	-	-	HYPH
cord-010027-r0tl01kq	815	9	DR	DR	NNP
cord-010027-r0tl01kq	815	10	positive	positive	JJ
cord-010027-r0tl01kq	815	11	M1	M1	NNP
cord-010027-r0tl01kq	815	12	macrophages	macrophage	NNS
cord-010027-r0tl01kq	815	13	exhibited	exhibit	VBD
cord-010027-r0tl01kq	815	14	a	a	DT
cord-010027-r0tl01kq	815	15	better	well	JJR
cord-010027-r0tl01kq	815	16	response	response	NN
cord-010027-r0tl01kq	815	17	to	to	IN
cord-010027-r0tl01kq	815	18	SCRT	SCRT	NNP
cord-010027-r0tl01kq	815	19	with	with	IN
cord-010027-r0tl01kq	815	20	a	a	DT
cord-010027-r0tl01kq	815	21	median	median	JJ
cord-010027-r0tl01kq	815	22	80	80	CD
cord-010027-r0tl01kq	815	23	%	%	NN
cord-010027-r0tl01kq	815	24	reduction	reduction	NN
cord-010027-r0tl01kq	815	25	in	in	IN
cord-010027-r0tl01kq	815	26	tumour	tumour	NN
cord-010027-r0tl01kq	815	27	cell	cell	NN
cord-010027-r0tl01kq	815	28	density	density	NN
cord-010027-r0tl01kq	815	29	(	(	-LRB-
cord-010027-r0tl01kq	815	30	IQR	IQR	NNP
cord-010027-r0tl01kq	815	31	47	47	CD
cord-010027-r0tl01kq	815	32	to	to	IN
cord-010027-r0tl01kq	815	33	85	85	CD
cord-010027-r0tl01kq	815	34	)	)	-RRB-
cord-010027-r0tl01kq	815	35	.	.	.
cord-010027-r0tl01kq	816	1	Those	those	DT
cord-010027-r0tl01kq	816	2	with	with	IN
cord-010027-r0tl01kq	816	3	a	a	DT
cord-010027-r0tl01kq	816	4	high	high	JJ
cord-010027-r0tl01kq	816	5	score	score	NN
cord-010027-r0tl01kq	816	6	exhibited	exhibit	VBD
cord-010027-r0tl01kq	816	7	a	a	DT
cord-010027-r0tl01kq	816	8	poor	poor	JJ
cord-010027-r0tl01kq	816	9	response	response	NN
cord-010027-r0tl01kq	816	10	with	with	IN
cord-010027-r0tl01kq	816	11	only	only	RB
cord-010027-r0tl01kq	816	12	a	a	DT
cord-010027-r0tl01kq	816	13	20	20	CD
cord-010027-r0tl01kq	816	14	%	%	NN
cord-010027-r0tl01kq	816	15	reduction	reduction	NN
cord-010027-r0tl01kq	816	16	(	(	-LRB-
cord-010027-r0tl01kq	816	17	IQR	IQR	NNP
cord-010027-r0tl01kq	816	18	0	0	CD
cord-010027-r0tl01kq	816	19	to	to	IN
cord-010027-r0tl01kq	816	20	49	49	CD
cord-010027-r0tl01kq	816	21	,	,	,
cord-010027-r0tl01kq	816	22	p=0·017	p=0·017	NNP
cord-010027-r0tl01kq	816	23	)	)	-RRB-
cord-010027-r0tl01kq	816	24	.	.	.
cord-010027-r0tl01kq	817	1	No	no	DT
cord-010027-r0tl01kq	817	2	such	such	JJ
cord-010027-r0tl01kq	817	3	trends	trend	NNS
cord-010027-r0tl01kq	817	4	were	be	VBD
cord-010027-r0tl01kq	817	5	observed	observe	VBN
cord-010027-r0tl01kq	817	6	for	for	IN
cord-010027-r0tl01kq	817	7	CD163	CD163	NNP
cord-010027-r0tl01kq	817	8	+	+	SYM
cord-010027-r0tl01kq	817	9	M2	M2	NNP
cord-010027-r0tl01kq	817	10	macrophages	macrophage	NNS
cord-010027-r0tl01kq	817	11	.	.	.
cord-010027-r0tl01kq	818	1	The	the	DT
cord-010027-r0tl01kq	818	2	ratio	ratio	NN
cord-010027-r0tl01kq	818	3	of	of	IN
cord-010027-r0tl01kq	818	4	HLA	HLA	NNP
cord-010027-r0tl01kq	818	5	-	-	HYPH
cord-010027-r0tl01kq	818	6	DR+	DR+	NNP
cord-010027-r0tl01kq	818	7	to	to	IN
cord-010027-r0tl01kq	818	8	CD163	CD163	NNP
cord-010027-r0tl01kq	818	9	+	+	CC
cord-010027-r0tl01kq	818	10	macrophages	macrophage	NNS
cord-010027-r0tl01kq	818	11	for	for	IN
cord-010027-r0tl01kq	818	12	biopsy	biopsy	NN
cord-010027-r0tl01kq	818	13	and	and	CC
cord-010027-r0tl01kq	818	14	resection	resection	NN
cord-010027-r0tl01kq	818	15	samples	sample	NNS
cord-010027-r0tl01kq	818	16	was	be	VBD
cord-010027-r0tl01kq	818	17	significantly	significantly	RB
cord-010027-r0tl01kq	818	18	different	different	JJ
cord-010027-r0tl01kq	818	19	showing	show	VBG
cord-010027-r0tl01kq	818	20	a	a	DT
cord-010027-r0tl01kq	818	21	drop	drop	NN
cord-010027-r0tl01kq	818	22	in	in	IN
cord-010027-r0tl01kq	818	23	the	the	DT
cord-010027-r0tl01kq	818	24	HLA	HLA	NNP
cord-010027-r0tl01kq	818	25	-	-	HYPH
cord-010027-r0tl01kq	818	26	DR	DR	NNP
cord-010027-r0tl01kq	818	27	positive	positive	JJ
cord-010027-r0tl01kq	818	28	macrophages	macrophage	NNS
cord-010027-r0tl01kq	818	29	in	in	IN
cord-010027-r0tl01kq	818	30	the	the	DT
cord-010027-r0tl01kq	818	31	resection	resection	NN
cord-010027-r0tl01kq	818	32	samples	sample	NNS
cord-010027-r0tl01kq	818	33	(	(	-LRB-
cord-010027-r0tl01kq	818	34	biopsy	biopsy	JJ
cord-010027-r0tl01kq	818	35	median	median	NN
cord-010027-r0tl01kq	818	36	2·53	2·53	CD
cord-010027-r0tl01kq	818	37	,	,	,
cord-010027-r0tl01kq	818	38	IQR	IQR	NNP
cord-010027-r0tl01kq	818	39	1.98	1.98	CD
cord-010027-r0tl01kq	818	40	to	to	IN
cord-010027-r0tl01kq	818	41	3.08	3.08	CD
cord-010027-r0tl01kq	818	42	;	;	:
cord-010027-r0tl01kq	818	43	resection	resection	NN
cord-010027-r0tl01kq	818	44	median	median	NN
cord-010027-r0tl01kq	818	45	1·38	1·38	CD
cord-010027-r0tl01kq	818	46	,	,	,
cord-010027-r0tl01kq	818	47	IQR	IQR	NNP
cord-010027-r0tl01kq	818	48	0.96	0.96	CD
cord-010027-r0tl01kq	818	49	to	to	IN
cord-010027-r0tl01kq	818	50	1.80	1.80	CD
cord-010027-r0tl01kq	818	51	;	;	:
cord-010027-r0tl01kq	818	52	p=0·024	p=0·024	NN
cord-010027-r0tl01kq	818	53	)	)	-RRB-
cord-010027-r0tl01kq	818	54	.	.	.
cord-010027-r0tl01kq	819	1	Assessment	assessment	NN
cord-010027-r0tl01kq	819	2	of	of	IN
cord-010027-r0tl01kq	819	3	macrophage	macrophage	NN
cord-010027-r0tl01kq	819	4	subpopulations	subpopulation	NNS
cord-010027-r0tl01kq	819	5	in	in	IN
cord-010027-r0tl01kq	819	6	pre	pre	JJ
cord-010027-r0tl01kq	819	7	-	-	JJ
cord-010027-r0tl01kq	819	8	treatment	treatment	JJ
cord-010027-r0tl01kq	819	9	biopsies	biopsy	NNS
cord-010027-r0tl01kq	819	10	appears	appear	VBZ
cord-010027-r0tl01kq	819	11	to	to	TO
cord-010027-r0tl01kq	819	12	predict	predict	VB
cord-010027-r0tl01kq	819	13	the	the	DT
cord-010027-r0tl01kq	819	14	degree	degree	NN
cord-010027-r0tl01kq	819	15	of	of	IN
cord-010027-r0tl01kq	819	16	response	response	NN
cord-010027-r0tl01kq	819	17	to	to	IN
cord-010027-r0tl01kq	819	18	SCRT	SCRT	NNP
cord-010027-r0tl01kq	819	19	in	in	IN
cord-010027-r0tl01kq	819	20	LARC	LARC	NNP
cord-010027-r0tl01kq	819	21	.	.	.
cord-010027-r0tl01kq	820	1	Further	further	JJ
cord-010027-r0tl01kq	820	2	investigation	investigation	NN
cord-010027-r0tl01kq	820	3	to	to	TO
cord-010027-r0tl01kq	820	4	validate	validate	VB
cord-010027-r0tl01kq	820	5	these	these	DT
cord-010027-r0tl01kq	820	6	findings	finding	NNS
cord-010027-r0tl01kq	820	7	is	be	VBZ
cord-010027-r0tl01kq	820	8	now	now	RB
cord-010027-r0tl01kq	820	9	required	require	VBN
cord-010027-r0tl01kq	820	10	prior	prior	RB
cord-010027-r0tl01kq	820	11	to	to	IN
cord-010027-r0tl01kq	820	12	developing	develop	VBG
cord-010027-r0tl01kq	820	13	a	a	DT
cord-010027-r0tl01kq	820	14	predictive	predictive	JJ
cord-010027-r0tl01kq	820	15	test	test	NN
cord-010027-r0tl01kq	820	16	for	for	IN
cord-010027-r0tl01kq	820	17	use	use	NN
cord-010027-r0tl01kq	820	18	in	in	IN
cord-010027-r0tl01kq	820	19	routine	routine	JJ
cord-010027-r0tl01kq	820	20	clinical	clinical	JJ
cord-010027-r0tl01kq	820	21	practice	practice	NN
cord-010027-r0tl01kq	820	22	.	.	.
cord-010027-r0tl01kq	821	1	Patients	patient	NNS
cord-010027-r0tl01kq	821	2	with	with	IN
cord-010027-r0tl01kq	821	3	a	a	DT
cord-010027-r0tl01kq	821	4	poor	poor	JJ
cord-010027-r0tl01kq	821	5	predicted	predict	VBN
cord-010027-r0tl01kq	821	6	response	response	NN
cord-010027-r0tl01kq	821	7	could	could	MD
cord-010027-r0tl01kq	821	8	avoid	avoid	VB
cord-010027-r0tl01kq	821	9	toxic	toxic	JJ
cord-010027-r0tl01kq	821	10	and	and	CC
cord-010027-r0tl01kq	821	11	costly	costly	JJ
cord-010027-r0tl01kq	821	12	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	821	13	and	and	CC
cord-010027-r0tl01kq	821	14	undergo	undergo	VB
cord-010027-r0tl01kq	821	15	alternative	alternative	JJ
cord-010027-r0tl01kq	821	16	strategies	strategy	NNS
cord-010027-r0tl01kq	821	17	including	include	VBG
cord-010027-r0tl01kq	821	18	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	821	19	.	.	.
cord-010027-r0tl01kq	822	1	Next	next	JJ
cord-010027-r0tl01kq	822	2	-	-	HYPH
cord-010027-r0tl01kq	822	3	generation	generation	NN
cord-010027-r0tl01kq	822	4	sequencing	sequencing	NN
cord-010027-r0tl01kq	822	5	technologies	technology	NNS
cord-010027-r0tl01kq	822	6	(	(	-LRB-
cord-010027-r0tl01kq	822	7	e.g.	e.g.	RB
cord-010027-r0tl01kq	822	8	16S	16S	NNP
cord-010027-r0tl01kq	822	9	profiling	profiling	NN
cord-010027-r0tl01kq	822	10	)	)	-RRB-
cord-010027-r0tl01kq	822	11	are	be	VBP
cord-010027-r0tl01kq	822	12	increasingly	increasingly	RB
cord-010027-r0tl01kq	822	13	used	use	VBN
cord-010027-r0tl01kq	822	14	to	to	TO
cord-010027-r0tl01kq	822	15	investigate	investigate	VB
cord-010027-r0tl01kq	822	16	complex	complex	JJ
cord-010027-r0tl01kq	822	17	bacterial	bacterial	JJ
cord-010027-r0tl01kq	822	18	communities	community	NNS
cord-010027-r0tl01kq	822	19	.	.	.
cord-010027-r0tl01kq	823	1	They	-PRON-	PRP
cord-010027-r0tl01kq	823	2	have	have	VBP
cord-010027-r0tl01kq	823	3	advantages	advantage	NNS
cord-010027-r0tl01kq	823	4	over	over	IN
cord-010027-r0tl01kq	823	5	classical	classical	JJ
cord-010027-r0tl01kq	823	6	methods	method	NNS
cord-010027-r0tl01kq	823	7	,	,	,
cord-010027-r0tl01kq	823	8	as	as	IN
cord-010027-r0tl01kq	823	9	a	a	DT
cord-010027-r0tl01kq	823	10	significant	significant	JJ
cord-010027-r0tl01kq	823	11	proportion	proportion	NN
cord-010027-r0tl01kq	823	12	of	of	IN
cord-010027-r0tl01kq	823	13	bacteria	bacteria	NNS
cord-010027-r0tl01kq	823	14	are	be	VBP
cord-010027-r0tl01kq	823	15	'	'	``
cord-010027-r0tl01kq	823	16	non	non	JJ
cord-010027-r0tl01kq	823	17	-	-	JJ
cord-010027-r0tl01kq	823	18	culturable	culturable	JJ
cord-010027-r0tl01kq	823	19	'	'	''
cord-010027-r0tl01kq	823	20	.	.	.
cord-010027-r0tl01kq	824	1	However	however	RB
cord-010027-r0tl01kq	824	2	,	,	,
cord-010027-r0tl01kq	824	3	they	-PRON-	PRP
cord-010027-r0tl01kq	824	4	do	do	VBP
cord-010027-r0tl01kq	824	5	not	not	RB
cord-010027-r0tl01kq	824	6	distinguish	distinguish	VB
cord-010027-r0tl01kq	824	7	'	'	``
cord-010027-r0tl01kq	824	8	viable	viable	JJ
cord-010027-r0tl01kq	824	9	'	'	''
cord-010027-r0tl01kq	824	10	and	and	CC
cord-010027-r0tl01kq	824	11	'	'	``
cord-010027-r0tl01kq	824	12	non	non	JJ
cord-010027-r0tl01kq	824	13	-	-	JJ
cord-010027-r0tl01kq	824	14	viable	viable	JJ
cord-010027-r0tl01kq	824	15	'	'	''
cord-010027-r0tl01kq	824	16	populations	population	NNS
cord-010027-r0tl01kq	824	17	,	,	,
cord-010027-r0tl01kq	824	18	which	which	WDT
cord-010027-r0tl01kq	824	19	may	may	MD
cord-010027-r0tl01kq	824	20	skew	skew	VB
cord-010027-r0tl01kq	824	21	results	result	NNS
cord-010027-r0tl01kq	824	22	,	,	,
cord-010027-r0tl01kq	824	23	particularly	particularly	RB
cord-010027-r0tl01kq	824	24	following	follow	VBG
cord-010027-r0tl01kq	824	25	antibiotic	antibiotic	JJ
cord-010027-r0tl01kq	824	26	exposure	exposure	NN
cord-010027-r0tl01kq	824	27	.	.	.
cord-010027-r0tl01kq	825	1	Here	here	RB
cord-010027-r0tl01kq	825	2	we	-PRON-	PRP
cord-010027-r0tl01kq	825	3	report	report	VBP
cord-010027-r0tl01kq	825	4	culture	culture	NN
cord-010027-r0tl01kq	825	5	and	and	CC
cord-010027-r0tl01kq	825	6	16S	16s	JJ
cord-010027-r0tl01kq	825	7	data	datum	NNS
cord-010027-r0tl01kq	825	8	from	from	IN
cord-010027-r0tl01kq	825	9	a	a	DT
cord-010027-r0tl01kq	825	10	clinically	clinically	RB
cord-010027-r0tl01kq	825	11	reflective	reflective	JJ
cord-010027-r0tl01kq	825	12	human	human	JJ
cord-010027-r0tl01kq	825	13	gut	gut	NN
cord-010027-r0tl01kq	825	14	model	model	NN
cord-010027-r0tl01kq	825	15	,	,	,
cord-010027-r0tl01kq	825	16	describing	describe	VBG
cord-010027-r0tl01kq	825	17	changes	change	NNS
cord-010027-r0tl01kq	825	18	in	in	IN
cord-010027-r0tl01kq	825	19	the	the	DT
cord-010027-r0tl01kq	825	20	gut	gut	NN
cord-010027-r0tl01kq	825	21	microbiota	microbiota	NN
cord-010027-r0tl01kq	825	22	following	follow	VBG
cord-010027-r0tl01kq	825	23	exposure	exposure	NN
cord-010027-r0tl01kq	825	24	to	to	IN
cord-010027-r0tl01kq	825	25	multiple	multiple	JJ
cord-010027-r0tl01kq	825	26	antibiotics	antibiotic	NNS
cord-010027-r0tl01kq	825	27	.	.	.
cord-010027-r0tl01kq	826	1	A	a	DT
cord-010027-r0tl01kq	826	2	triple	triple	JJ
cord-010027-r0tl01kq	826	3	-	-	HYPH
cord-010027-r0tl01kq	826	4	stage	stage	NN
cord-010027-r0tl01kq	826	5	chemostat	chemostat	NN
cord-010027-r0tl01kq	826	6	model	model	NN
cord-010027-r0tl01kq	826	7	was	be	VBD
cord-010027-r0tl01kq	826	8	inoculated	inoculate	VBN
cord-010027-r0tl01kq	826	9	with	with	IN
cord-010027-r0tl01kq	826	10	pooled	pool	VBN
cord-010027-r0tl01kq	826	11	human	human	JJ
cord-010027-r0tl01kq	826	12	faeces	faece	NNS
cord-010027-r0tl01kq	826	13	from	from	IN
cord-010027-r0tl01kq	826	14	healthy	healthy	JJ
cord-010027-r0tl01kq	826	15	volunteers	volunteer	NNS
cord-010027-r0tl01kq	826	16	to	to	TO
cord-010027-r0tl01kq	826	17	establish	establish	VB
cord-010027-r0tl01kq	826	18	gut	gut	NN
cord-010027-r0tl01kq	826	19	microbiota	microbiota	NN
cord-010027-r0tl01kq	826	20	populations	population	NNS
cord-010027-r0tl01kq	826	21	.	.	.
cord-010027-r0tl01kq	827	1	The	the	DT
cord-010027-r0tl01kq	827	2	model	model	NN
cord-010027-r0tl01kq	827	3	was	be	VBD
cord-010027-r0tl01kq	827	4	sequentially	sequentially	RB
cord-010027-r0tl01kq	827	5	exposed	expose	VBN
cord-010027-r0tl01kq	827	6	to	to	IN
cord-010027-r0tl01kq	827	7	clindamycin	clindamycin	NN
cord-010027-r0tl01kq	827	8	(	(	-LRB-
cord-010027-r0tl01kq	827	9	33.9	33.9	CD
cord-010027-r0tl01kq	827	10	mg	mg	NNP
cord-010027-r0tl01kq	827	11	/	/	SYM
cord-010027-r0tl01kq	827	12	L	L	NNP
cord-010027-r0tl01kq	827	13	,	,	,
cord-010027-r0tl01kq	827	14	QDS	QDS	NNP
cord-010027-r0tl01kq	827	15	,	,	,
cord-010027-r0tl01kq	827	16	7days	7days	CD
cord-010027-r0tl01kq	827	17	)	)	-RRB-
cord-010027-r0tl01kq	827	18	,	,	,
cord-010027-r0tl01kq	827	19	vancomycin	vancomycin	FW
cord-010027-r0tl01kq	827	20	(	(	-LRB-
cord-010027-r0tl01kq	827	21	125mg	125mg	NNP
cord-010027-r0tl01kq	827	22	/	/	SYM
cord-010027-r0tl01kq	827	23	L	L	NNP
cord-010027-r0tl01kq	827	24	,	,	,
cord-010027-r0tl01kq	827	25	QDS	QDS	NNP
cord-010027-r0tl01kq	827	26	,	,	,
cord-010027-r0tl01kq	827	27	7days	7days	CD
cord-010027-r0tl01kq	827	28	)	)	-RRB-
cord-010027-r0tl01kq	827	29	and	and	CC
cord-010027-r0tl01kq	827	30	fidaxomicin	fidaxomicin	NNP
cord-010027-r0tl01kq	827	31	(	(	-LRB-
cord-010027-r0tl01kq	827	32	200	200	CD
cord-010027-r0tl01kq	827	33	mg	mg	NNP
cord-010027-r0tl01kq	827	34	/	/	SYM
cord-010027-r0tl01kq	827	35	L	L	NNP
cord-010027-r0tl01kq	827	36	,	,	,
cord-010027-r0tl01kq	827	37	BD	BD	NNP
cord-010027-r0tl01kq	827	38	,	,	,
cord-010027-r0tl01kq	827	39	7	7	CD
cord-010027-r0tl01kq	827	40	days	day	NNS
cord-010027-r0tl01kq	827	41	)	)	-RRB-
cord-010027-r0tl01kq	827	42	.	.	.
cord-010027-r0tl01kq	828	1	Specific	specific	JJ
cord-010027-r0tl01kq	828	2	bacterial	bacterial	JJ
cord-010027-r0tl01kq	828	3	populations	population	NNS
cord-010027-r0tl01kq	828	4	were	be	VBD
cord-010027-r0tl01kq	828	5	enumerated	enumerate	VBN
cord-010027-r0tl01kq	828	6	daily	daily	RB
cord-010027-r0tl01kq	828	7	on	on	IN
cord-010027-r0tl01kq	828	8	selective	selective	JJ
cord-010027-r0tl01kq	828	9	agars	agar	NNS
cord-010027-r0tl01kq	828	10	.	.	.
cord-010027-r0tl01kq	829	1	Periodically	periodically	RB
cord-010027-r0tl01kq	829	2	,	,	,
cord-010027-r0tl01kq	829	3	16S	16S	NNP
cord-010027-r0tl01kq	829	4	profiling	profiling	NN
cord-010027-r0tl01kq	829	5	of	of	IN
cord-010027-r0tl01kq	829	6	gut	gut	NN
cord-010027-r0tl01kq	829	7	model	model	NN
cord-010027-r0tl01kq	829	8	samples	sample	NNS
cord-010027-r0tl01kq	829	9	was	be	VBD
cord-010027-r0tl01kq	829	10	performed	perform	VBN
cord-010027-r0tl01kq	829	11	;	;	:
cord-010027-r0tl01kq	829	12	DNA	DNA	NNP
cord-010027-r0tl01kq	829	13	was	be	VBD
cord-010027-r0tl01kq	829	14	extracted	extract	VBN
cord-010027-r0tl01kq	829	15	on	on	IN
cord-010027-r0tl01kq	829	16	a	a	DT
cord-010027-r0tl01kq	829	17	QIAXtractor	qiaxtractor	NN
cord-010027-r0tl01kq	829	18	,	,	,
cord-010027-r0tl01kq	829	19	16S	16S	NNP
cord-010027-r0tl01kq	829	20	V4	V4	NNP
cord-010027-r0tl01kq	829	21	PCR	PCR	NNP
cord-010027-r0tl01kq	829	22	products	product	NNS
cord-010027-r0tl01kq	829	23	were	be	VBD
cord-010027-r0tl01kq	829	24	sequenced	sequence	VBN
cord-010027-r0tl01kq	829	25	on	on	IN
cord-010027-r0tl01kq	829	26	an	an	DT
cord-010027-r0tl01kq	829	27	Illumina	Illumina	NNP
cord-010027-r0tl01kq	829	28	MiSeq	MiSeq	NNP
cord-010027-r0tl01kq	829	29	,	,	,
cord-010027-r0tl01kq	829	30	and	and	CC
cord-010027-r0tl01kq	829	31	resulting	result	VBG
cord-010027-r0tl01kq	829	32	data	datum	NNS
cord-010027-r0tl01kq	829	33	were	be	VBD
cord-010027-r0tl01kq	829	34	analysed	analyse	VBN
cord-010027-r0tl01kq	829	35	using	use	VBG
cord-010027-r0tl01kq	829	36	QIIME	QIIME	NNP
cord-010027-r0tl01kq	829	37	.	.	.
cord-010027-r0tl01kq	830	1	Both	both	DT
cord-010027-r0tl01kq	830	2	culture	culture	NN
cord-010027-r0tl01kq	830	3	and	and	CC
cord-010027-r0tl01kq	830	4	16S	16s	JJ
cord-010027-r0tl01kq	830	5	profiling	profiling	NN
cord-010027-r0tl01kq	830	6	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	830	7	marked	marked	JJ
cord-010027-r0tl01kq	830	8	alterations	alteration	NNS
cord-010027-r0tl01kq	830	9	in	in	IN
cord-010027-r0tl01kq	830	10	gut	gut	NN
cord-010027-r0tl01kq	830	11	microbiota	microbiota	NN
cord-010027-r0tl01kq	830	12	populations	population	NNS
cord-010027-r0tl01kq	830	13	following	follow	VBG
cord-010027-r0tl01kq	830	14	antibiotic	antibiotic	JJ
cord-010027-r0tl01kq	830	15	exposure	exposure	NN
cord-010027-r0tl01kq	830	16	.	.	.
cord-010027-r0tl01kq	831	1	For	for	IN
cord-010027-r0tl01kq	831	2	many	many	JJ
cord-010027-r0tl01kq	831	3	populations	population	NNS
cord-010027-r0tl01kq	831	4	,	,	,
cord-010027-r0tl01kq	831	5	notably	notably	RB
cord-010027-r0tl01kq	831	6	bifidobacteria	bifidobacteria	NNP
cord-010027-r0tl01kq	831	7	and	and	CC
cord-010027-r0tl01kq	831	8	enterobacteria	enterobacteria	NNP
cord-010027-r0tl01kq	831	9	,	,	,
cord-010027-r0tl01kq	831	10	changes	change	NNS
cord-010027-r0tl01kq	831	11	seen	see	VBN
cord-010027-r0tl01kq	831	12	by	by	IN
cord-010027-r0tl01kq	831	13	culture	culture	NN
cord-010027-r0tl01kq	831	14	correlated	correlate	VBN
cord-010027-r0tl01kq	831	15	with	with	IN
cord-010027-r0tl01kq	831	16	16S	16s	JJ
cord-010027-r0tl01kq	831	17	profiling	profiling	NN
cord-010027-r0tl01kq	831	18	.	.	.
cord-010027-r0tl01kq	832	1	However	however	RB
cord-010027-r0tl01kq	832	2	,	,	,
cord-010027-r0tl01kq	832	3	as	as	IN
cord-010027-r0tl01kq	832	4	culture	culture	NN
cord-010027-r0tl01kq	832	5	describes	describe	VBZ
cord-010027-r0tl01kq	832	6	numerical	numerical	JJ
cord-010027-r0tl01kq	832	7	changes	change	NNS
cord-010027-r0tl01kq	832	8	in	in	IN
cord-010027-r0tl01kq	832	9	populations	population	NNS
cord-010027-r0tl01kq	832	10	,	,	,
cord-010027-r0tl01kq	832	11	and	and	CC
cord-010027-r0tl01kq	832	12	16S	16S	NNP
cord-010027-r0tl01kq	832	13	profiling	profiling	NN
cord-010027-r0tl01kq	832	14	describes	describe	VBZ
cord-010027-r0tl01kq	832	15	proportional	proportional	JJ
cord-010027-r0tl01kq	832	16	changes	change	NNS
cord-010027-r0tl01kq	832	17	,	,	,
cord-010027-r0tl01kq	832	18	results	result	NNS
cord-010027-r0tl01kq	832	19	are	be	VBP
cord-010027-r0tl01kq	832	20	not	not	RB
cord-010027-r0tl01kq	832	21	always	always	RB
cord-010027-r0tl01kq	832	22	directly	directly	RB
cord-010027-r0tl01kq	832	23	comparable	comparable	JJ
cord-010027-r0tl01kq	832	24	.	.	.
cord-010027-r0tl01kq	833	1	16S	16S	NNP
cord-010027-r0tl01kq	833	2	profiling	profiling	NN
cord-010027-r0tl01kq	833	3	greatly	greatly	RB
cord-010027-r0tl01kq	833	4	increased	increase	VBN
cord-010027-r0tl01kq	833	5	microbiome	microbiome	NN
cord-010027-r0tl01kq	833	6	coverage	coverage	NN
cord-010027-r0tl01kq	833	7	,	,	,
cord-010027-r0tl01kq	833	8	particularly	particularly	RB
cord-010027-r0tl01kq	833	9	for	for	IN
cord-010027-r0tl01kq	833	10	clostridia	clostridia	NNP
cord-010027-r0tl01kq	833	11	.	.	.
cord-010027-r0tl01kq	834	1	Population	population	NN
cord-010027-r0tl01kq	834	2	diversity	diversity	NN
cord-010027-r0tl01kq	834	3	(	(	-LRB-
cord-010027-r0tl01kq	834	4	number	number	NN
cord-010027-r0tl01kq	834	5	of	of	IN
cord-010027-r0tl01kq	834	6	observed	observed	JJ
cord-010027-r0tl01kq	834	7	species	specie	NNS
cord-010027-r0tl01kq	834	8	and	and	CC
cord-010027-r0tl01kq	834	9	Shannon	Shannon	NNP
cord-010027-r0tl01kq	834	10	index	index	NN
cord-010027-r0tl01kq	834	11	)	)	-RRB-
cord-010027-r0tl01kq	834	12	decreased	decrease	VBD
cord-010027-r0tl01kq	834	13	with	with	IN
cord-010027-r0tl01kq	834	14	sequential	sequential	JJ
cord-010027-r0tl01kq	834	15	antibiotic	antibiotic	JJ
cord-010027-r0tl01kq	834	16	exposure	exposure	NN
cord-010027-r0tl01kq	834	17	.	.	.
cord-010027-r0tl01kq	835	1	Use	use	NN
cord-010027-r0tl01kq	835	2	of	of	IN
cord-010027-r0tl01kq	835	3	culture	culture	NN
cord-010027-r0tl01kq	835	4	and	and	CC
cord-010027-r0tl01kq	835	5	molecular	molecular	JJ
cord-010027-r0tl01kq	835	6	methods	method	NNS
cord-010027-r0tl01kq	835	7	in	in	IN
cord-010027-r0tl01kq	835	8	tandem	tandem	NN
cord-010027-r0tl01kq	835	9	can	can	MD
cord-010027-r0tl01kq	835	10	greatly	greatly	RB
cord-010027-r0tl01kq	835	11	increase	increase	VB
cord-010027-r0tl01kq	835	12	understanding	understanding	NN
cord-010027-r0tl01kq	835	13	of	of	IN
cord-010027-r0tl01kq	835	14	changes	change	NNS
cord-010027-r0tl01kq	835	15	occurring	occur	VBG
cord-010027-r0tl01kq	835	16	in	in	IN
cord-010027-r0tl01kq	835	17	complex	complex	JJ
cord-010027-r0tl01kq	835	18	microbial	microbial	JJ
cord-010027-r0tl01kq	835	19	populations	population	NNS
cord-010027-r0tl01kq	835	20	.	.	.
cord-010027-r0tl01kq	836	1	Barrett	Barrett	NNP
cord-010027-r0tl01kq	836	2	's	's	POS
cord-010027-r0tl01kq	836	3	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	836	4	is	be	VBZ
cord-010027-r0tl01kq	836	5	the	the	DT
cord-010027-r0tl01kq	836	6	erosive	erosive	JJ
cord-010027-r0tl01kq	836	7	replacement	replacement	NN
cord-010027-r0tl01kq	836	8	of	of	IN
cord-010027-r0tl01kq	836	9	the	the	DT
cord-010027-r0tl01kq	836	10	normal	normal	JJ
cord-010027-r0tl01kq	836	11	squamous	squamous	JJ
cord-010027-r0tl01kq	836	12	oesophageal	oesophageal	JJ
cord-010027-r0tl01kq	836	13	lining	lining	NN
cord-010027-r0tl01kq	836	14	with	with	IN
cord-010027-r0tl01kq	836	15	a	a	DT
cord-010027-r0tl01kq	836	16	glandular	glandular	JJ
cord-010027-r0tl01kq	836	17	epithelium	epithelium	NN
cord-010027-r0tl01kq	836	18	and	and	CC
cord-010027-r0tl01kq	836	19	is	be	VBZ
cord-010027-r0tl01kq	836	20	the	the	DT
cord-010027-r0tl01kq	836	21	major	major	JJ
cord-010027-r0tl01kq	836	22	precursor	precursor	NN
cord-010027-r0tl01kq	836	23	of	of	IN
cord-010027-r0tl01kq	836	24	oesophageal	oesophageal	JJ
cord-010027-r0tl01kq	836	25	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	836	26	.	.	.
cord-010027-r0tl01kq	837	1	Barrett	Barrett	NNP
cord-010027-r0tl01kq	837	2	's	's	POS
cord-010027-r0tl01kq	837	3	patients	patient	NNS
cord-010027-r0tl01kq	837	4	are	be	VBP
cord-010027-r0tl01kq	837	5	enrolled	enrol	VBN
cord-010027-r0tl01kq	837	6	into	into	IN
cord-010027-r0tl01kq	837	7	active	active	JJ
cord-010027-r0tl01kq	837	8	surveillance	surveillance	NN
cord-010027-r0tl01kq	837	9	programmes	programme	NNS
cord-010027-r0tl01kq	837	10	in	in	IN
cord-010027-r0tl01kq	837	11	order	order	NN
cord-010027-r0tl01kq	837	12	to	to	TO
cord-010027-r0tl01kq	837	13	detect	detect	VB
cord-010027-r0tl01kq	837	14	and	and	CC
cord-010027-r0tl01kq	837	15	treat	treat	VB
cord-010027-r0tl01kq	837	16	oesophageal	oesophageal	JJ
cord-010027-r0tl01kq	837	17	cancer	cancer	NN
cord-010027-r0tl01kq	837	18	at	at	IN
cord-010027-r0tl01kq	837	19	an	an	DT
cord-010027-r0tl01kq	837	20	early	early	JJ
cord-010027-r0tl01kq	837	21	stage	stage	NN
cord-010027-r0tl01kq	837	22	.	.	.
cord-010027-r0tl01kq	838	1	Surveillance	surveillance	NN
cord-010027-r0tl01kq	838	2	however	however	RB
cord-010027-r0tl01kq	838	3	is	be	VBZ
cord-010027-r0tl01kq	838	4	costly	costly	JJ
cord-010027-r0tl01kq	838	5	and	and	CC
cord-010027-r0tl01kq	838	6	burdening	burden	VBG
cord-010027-r0tl01kq	838	7	to	to	IN
cord-010027-r0tl01kq	838	8	patients	patient	NNS
cord-010027-r0tl01kq	838	9	.	.	.
cord-010027-r0tl01kq	839	1	To	to	TO
cord-010027-r0tl01kq	839	2	improve	improve	VB
cord-010027-r0tl01kq	839	3	screening	screen	VBG
cord-010027-r0tl01kq	839	4	efficacy	efficacy	NN
cord-010027-r0tl01kq	839	5	there	there	EX
cord-010027-r0tl01kq	839	6	is	be	VBZ
cord-010027-r0tl01kq	839	7	an	an	DT
cord-010027-r0tl01kq	839	8	acute	acute	JJ
cord-010027-r0tl01kq	839	9	need	need	NN
cord-010027-r0tl01kq	839	10	for	for	IN
cord-010027-r0tl01kq	839	11	accurate	accurate	JJ
cord-010027-r0tl01kq	839	12	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	839	13	of	of	IN
cord-010027-r0tl01kq	839	14	cancer	cancer	NN
cord-010027-r0tl01kq	839	15	progression	progression	NN
cord-010027-r0tl01kq	839	16	risk	risk	NN
cord-010027-r0tl01kq	839	17	in	in	IN
cord-010027-r0tl01kq	839	18	Barrett	Barrett	NNP
cord-010027-r0tl01kq	839	19	's	's	POS
cord-010027-r0tl01kq	839	20	patients	patient	NNS
cord-010027-r0tl01kq	839	21	.	.	.
cord-010027-r0tl01kq	840	1	Understanding	understand	VBG
cord-010027-r0tl01kq	840	2	the	the	DT
cord-010027-r0tl01kq	840	3	pattern	pattern	NN
cord-010027-r0tl01kq	840	4	and	and	CC
cord-010027-r0tl01kq	840	5	pace	pace	NN
cord-010027-r0tl01kq	840	6	of	of	IN
cord-010027-r0tl01kq	840	7	clonal	clonal	JJ
cord-010027-r0tl01kq	840	8	evolution	evolution	NN
cord-010027-r0tl01kq	840	9	that	that	WDT
cord-010027-r0tl01kq	840	10	occurs	occur	VBZ
cord-010027-r0tl01kq	840	11	within	within	IN
cord-010027-r0tl01kq	840	12	the	the	DT
cord-010027-r0tl01kq	840	13	Barrett	Barrett	NNP
cord-010027-r0tl01kq	840	14	's	's	POS
cord-010027-r0tl01kq	840	15	segment	segment	NN
cord-010027-r0tl01kq	840	16	is	be	VBZ
cord-010027-r0tl01kq	840	17	a	a	DT
cord-010027-r0tl01kq	840	18	key	key	JJ
cord-010027-r0tl01kq	840	19	step	step	NN
cord-010027-r0tl01kq	840	20	towards	towards	IN
cord-010027-r0tl01kq	840	21	achieving	achieve	VBG
cord-010027-r0tl01kq	840	22	this	this	DT
cord-010027-r0tl01kq	840	23	goal	goal	NN
cord-010027-r0tl01kq	840	24	.	.	.
cord-010027-r0tl01kq	841	1	Opinion	opinion	NN
cord-010027-r0tl01kq	841	2	is	be	VBZ
cord-010027-r0tl01kq	841	3	divided	divide	VBN
cord-010027-r0tl01kq	841	4	over	over	IN
cord-010027-r0tl01kq	841	5	whether	whether	IN
cord-010027-r0tl01kq	841	6	goblet	goblet	NN
cord-010027-r0tl01kq	841	7	cells	cell	NNS
cord-010027-r0tl01kq	841	8	(	(	-LRB-
cord-010027-r0tl01kq	841	9	intestinal	intestinal	JJ
cord-010027-r0tl01kq	841	10	metaplasia	metaplasia	NN
cord-010027-r0tl01kq	841	11	)	)	-RRB-
cord-010027-r0tl01kq	841	12	on	on	IN
cord-010027-r0tl01kq	841	13	oesophageal	oesophageal	JJ
cord-010027-r0tl01kq	841	14	biopsy	biopsy	NN
cord-010027-r0tl01kq	841	15	are	be	VBP
cord-010027-r0tl01kq	841	16	required	require	VBN
cord-010027-r0tl01kq	841	17	for	for	IN
cord-010027-r0tl01kq	841	18	a	a	DT
cord-010027-r0tl01kq	841	19	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	841	20	of	of	IN
cord-010027-r0tl01kq	841	21	Barrett	Barrett	NNP
cord-010027-r0tl01kq	841	22	's	's	POS
cord-010027-r0tl01kq	841	23	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	841	24	.	.	.
cord-010027-r0tl01kq	842	1	This	this	DT
cord-010027-r0tl01kq	842	2	is	be	VBZ
cord-010027-r0tl01kq	842	3	based	base	VBN
cord-010027-r0tl01kq	842	4	on	on	IN
cord-010027-r0tl01kq	842	5	the	the	DT
cord-010027-r0tl01kq	842	6	unproven	unproven	JJ
cord-010027-r0tl01kq	842	7	assumption	assumption	NN
cord-010027-r0tl01kq	842	8	that	that	IN
cord-010027-r0tl01kq	842	9	goblet	goblet	NN
cord-010027-r0tl01kq	842	10	cell	cell	NN
cord-010027-r0tl01kq	842	11	differentiation	differentiation	NN
cord-010027-r0tl01kq	842	12	marks	mark	NNS
cord-010027-r0tl01kq	842	13	increased	increase	VBD
cord-010027-r0tl01kq	842	14	cancer	cancer	NN
cord-010027-r0tl01kq	842	15	risk	risk	NN
cord-010027-r0tl01kq	842	16	in	in	IN
cord-010027-r0tl01kq	842	17	Barrett	Barrett	NNP
cord-010027-r0tl01kq	842	18	's	's	POS
cord-010027-r0tl01kq	842	19	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	842	20	patients	patient	NNS
cord-010027-r0tl01kq	842	21	.	.	.
cord-010027-r0tl01kq	843	1	We	-PRON-	PRP
cord-010027-r0tl01kq	843	2	have	have	VBP
cord-010027-r0tl01kq	843	3	investigated	investigate	VBN
cord-010027-r0tl01kq	843	4	the	the	DT
cord-010027-r0tl01kq	843	5	clonal	clonal	JJ
cord-010027-r0tl01kq	843	6	structure	structure	NN
cord-010027-r0tl01kq	843	7	of	of	IN
cord-010027-r0tl01kq	843	8	non	non	JJ
cord-010027-r0tl01kq	843	9	-	-	JJ
cord-010027-r0tl01kq	843	10	dysplastic	dysplastic	JJ
cord-010027-r0tl01kq	843	11	and	and	CC
cord-010027-r0tl01kq	843	12	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	843	13	Barrett	Barrett	NNP
cord-010027-r0tl01kq	843	14	's	's	POS
cord-010027-r0tl01kq	843	15	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	843	16	by	by	IN
cord-010027-r0tl01kq	843	17	combining	combine	VBG
cord-010027-r0tl01kq	843	18	state	state	NN
cord-010027-r0tl01kq	843	19	-	-	HYPH
cord-010027-r0tl01kq	843	20	of	of	IN
cord-010027-r0tl01kq	843	21	-	-	HYPH
cord-010027-r0tl01kq	843	22	the	the	DT
cord-010027-r0tl01kq	843	23	-	-	HYPH
cord-010027-r0tl01kq	843	24	art	art	NN
cord-010027-r0tl01kq	843	25	3D	3d	NN
cord-010027-r0tl01kq	843	26	modeling	modeling	NN
cord-010027-r0tl01kq	843	27	and	and	CC
cord-010027-r0tl01kq	843	28	genetic	genetic	JJ
cord-010027-r0tl01kq	843	29	lineage	lineage	NN
cord-010027-r0tl01kq	843	30	tracing	tracing	NN
cord-010027-r0tl01kq	843	31	.	.	.
cord-010027-r0tl01kq	844	1	By	by	IN
cord-010027-r0tl01kq	844	2	tracing	trace	VBG
cord-010027-r0tl01kq	844	3	the	the	DT
cord-010027-r0tl01kq	844	4	clonal	clonal	JJ
cord-010027-r0tl01kq	844	5	origin	origin	NN
cord-010027-r0tl01kq	844	6	of	of	IN
cord-010027-r0tl01kq	844	7	an	an	DT
cord-010027-r0tl01kq	844	8	early	early	JJ
cord-010027-r0tl01kq	844	9	oesophageal	oesophageal	JJ
cord-010027-r0tl01kq	844	10	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	844	11	through	through	IN
cord-010027-r0tl01kq	844	12	whole	whole	JJ
cord-010027-r0tl01kq	844	13	-	-	HYPH
cord-010027-r0tl01kq	844	14	exome	exome	NN
cord-010027-r0tl01kq	844	15	sequencing	sequencing	NN
cord-010027-r0tl01kq	844	16	and	and	CC
cord-010027-r0tl01kq	844	17	mitochondrial	mitochondrial	JJ
cord-010027-r0tl01kq	844	18	DNA	dna	NN
cord-010027-r0tl01kq	844	19	sequencing	sequencing	NN
cord-010027-r0tl01kq	844	20	,	,	,
cord-010027-r0tl01kq	844	21	we	-PRON-	PRP
cord-010027-r0tl01kq	844	22	find	find	VBP
cord-010027-r0tl01kq	844	23	that	that	IN
cord-010027-r0tl01kq	844	24	this	this	DT
cord-010027-r0tl01kq	844	25	cancer	cancer	NN
cord-010027-r0tl01kq	844	26	developed	develop	VBN
cord-010027-r0tl01kq	844	27	from	from	IN
cord-010027-r0tl01kq	844	28	non	non	JJ
cord-010027-r0tl01kq	844	29	-	-	JJ
cord-010027-r0tl01kq	844	30	goblet	goblet	JJ
cord-010027-r0tl01kq	844	31	columnar	columnar	JJ
cord-010027-r0tl01kq	844	32	epithelium	epithelium	NN
cord-010027-r0tl01kq	844	33	,	,	,
cord-010027-r0tl01kq	844	34	whereas	whereas	IN
cord-010027-r0tl01kq	844	35	the	the	DT
cord-010027-r0tl01kq	844	36	adjacent	adjacent	JJ
cord-010027-r0tl01kq	844	37	goblet	goblet	NN
cord-010027-r0tl01kq	844	38	-	-	HYPH
cord-010027-r0tl01kq	844	39	bearing	bear	VBG
cord-010027-r0tl01kq	844	40	mucosa	mucosa	NN
cord-010027-r0tl01kq	844	41	was	be	VBD
cord-010027-r0tl01kq	844	42	free	free	JJ
cord-010027-r0tl01kq	844	43	of	of	IN
cord-010027-r0tl01kq	844	44	oncogenic	oncogenic	JJ
cord-010027-r0tl01kq	844	45	mutations	mutation	NNS
cord-010027-r0tl01kq	844	46	.	.	.
cord-010027-r0tl01kq	845	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	845	2	results	result	NNS
cord-010027-r0tl01kq	845	3	have	have	VBP
cord-010027-r0tl01kq	845	4	important	important	JJ
cord-010027-r0tl01kq	845	5	implications	implication	NNS
cord-010027-r0tl01kq	845	6	for	for	IN
cord-010027-r0tl01kq	845	7	the	the	DT
cord-010027-r0tl01kq	845	8	harmonization	harmonization	NN
cord-010027-r0tl01kq	845	9	of	of	IN
cord-010027-r0tl01kq	845	10	the	the	DT
cord-010027-r0tl01kq	845	11	clinical	clinical	JJ
cord-010027-r0tl01kq	845	12	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	845	13	of	of	IN
cord-010027-r0tl01kq	845	14	Barrett	Barrett	NNP
cord-010027-r0tl01kq	845	15	's	's	POS
cord-010027-r0tl01kq	845	16	oesophagus	oesophagus	NN
cord-010027-r0tl01kq	845	17	.	.	.
cord-010027-r0tl01kq	846	1	Long	long	JJ
cord-010027-r0tl01kq	846	2	-	-	HYPH
cord-010027-r0tl01kq	846	3	course	course	NN
cord-010027-r0tl01kq	846	4	chemoradiotherapy	chemoradiotherapy	NN
cord-010027-r0tl01kq	846	5	(	(	-LRB-
cord-010027-r0tl01kq	846	6	CRT	CRT	NNP
cord-010027-r0tl01kq	846	7	)	)	-RRB-
cord-010027-r0tl01kq	846	8	is	be	VBZ
cord-010027-r0tl01kq	846	9	used	use	VBN
cord-010027-r0tl01kq	846	10	to	to	IN
cord-010027-r0tl01kq	846	11	down	down	IN
cord-010027-r0tl01kq	846	12	-	-	HYPH
cord-010027-r0tl01kq	846	13	stage	stage	NN
cord-010027-r0tl01kq	846	14	locally	locally	RB
cord-010027-r0tl01kq	846	15	-	-	HYPH
cord-010027-r0tl01kq	846	16	advanced	advance	VBN
cord-010027-r0tl01kq	846	17	rectal	rectal	JJ
cord-010027-r0tl01kq	846	18	cancer	cancer	NN
cord-010027-r0tl01kq	846	19	(	(	-LRB-
cord-010027-r0tl01kq	846	20	LARC	LARC	NNP
cord-010027-r0tl01kq	846	21	)	)	-RRB-
cord-010027-r0tl01kq	846	22	prior	prior	RB
cord-010027-r0tl01kq	846	23	to	to	IN
cord-010027-r0tl01kq	846	24	resection	resection	NN
cord-010027-r0tl01kq	846	25	.	.	.
cord-010027-r0tl01kq	847	1	An	an	DT
cord-010027-r0tl01kq	847	2	interval	interval	NN
cord-010027-r0tl01kq	847	3	period	period	NN
cord-010027-r0tl01kq	847	4	prior	prior	RB
cord-010027-r0tl01kq	847	5	to	to	IN
cord-010027-r0tl01kq	847	6	surgery	surgery	NN
cord-010027-r0tl01kq	847	7	allows	allow	VBZ
cord-010027-r0tl01kq	847	8	for	for	IN
cord-010027-r0tl01kq	847	9	tumour	tumour	NN
cord-010027-r0tl01kq	847	10	shrinkage	shrinkage	NN
cord-010027-r0tl01kq	847	11	to	to	TO
cord-010027-r0tl01kq	847	12	facilitate	facilitate	VB
cord-010027-r0tl01kq	847	13	surgical	surgical	JJ
cord-010027-r0tl01kq	847	14	removal	removal	NN
cord-010027-r0tl01kq	847	15	.	.	.
cord-010027-r0tl01kq	848	1	The	the	DT
cord-010027-r0tl01kq	848	2	optimal	optimal	JJ
cord-010027-r0tl01kq	848	3	time	time	NN
cord-010027-r0tl01kq	848	4	interval	interval	NN
cord-010027-r0tl01kq	848	5	remains	remain	VBZ
cord-010027-r0tl01kq	848	6	unclear	unclear	JJ
cord-010027-r0tl01kq	848	7	,	,	,
cord-010027-r0tl01kq	848	8	with	with	IN
cord-010027-r0tl01kq	848	9	little	little	JJ
cord-010027-r0tl01kq	848	10	high	high	JJ
cord-010027-r0tl01kq	848	11	-	-	HYPH
cord-010027-r0tl01kq	848	12	quality	quality	NN
cord-010027-r0tl01kq	848	13	evidence	evidence	NN
cord-010027-r0tl01kq	848	14	to	to	TO
cord-010027-r0tl01kq	848	15	guide	guide	VB
cord-010027-r0tl01kq	848	16	clinical	clinical	JJ
cord-010027-r0tl01kq	848	17	decisions	decision	NNS
cord-010027-r0tl01kq	848	18	about	about	IN
cord-010027-r0tl01kq	848	19	when	when	WRB
cord-010027-r0tl01kq	848	20	to	to	TO
cord-010027-r0tl01kq	848	21	operate	operate	VB
cord-010027-r0tl01kq	848	22	.	.	.
cord-010027-r0tl01kq	849	1	This	this	DT
cord-010027-r0tl01kq	849	2	study	study	NN
cord-010027-r0tl01kq	849	3	explores	explore	VBZ
cord-010027-r0tl01kq	849	4	the	the	DT
cord-010027-r0tl01kq	849	5	pathological	pathological	JJ
cord-010027-r0tl01kq	849	6	outcomes	outcome	NNS
cord-010027-r0tl01kq	849	7	from	from	IN
cord-010027-r0tl01kq	849	8	a	a	DT
cord-010027-r0tl01kq	849	9	pilot	pilot	NN
cord-010027-r0tl01kq	849	10	randomised	randomise	VBN
cord-010027-r0tl01kq	849	11	controlled	control	VBN
cord-010027-r0tl01kq	849	12	trial	trial	NN
cord-010027-r0tl01kq	849	13	comparing	compare	VBG
cord-010027-r0tl01kq	849	14	an	an	DT
cord-010027-r0tl01kq	849	15	interval	interval	NN
cord-010027-r0tl01kq	849	16	of	of	IN
cord-010027-r0tl01kq	849	17	6	6	CD
cord-010027-r0tl01kq	849	18	weeks	week	NNS
cord-010027-r0tl01kq	849	19	versus	versus	IN
cord-010027-r0tl01kq	849	20	12	12	CD
cord-010027-r0tl01kq	849	21	weeks	week	NNS
cord-010027-r0tl01kq	849	22	between	between	IN
cord-010027-r0tl01kq	849	23	CRT	CRT	NNP
cord-010027-r0tl01kq	849	24	and	and	CC
cord-010027-r0tl01kq	849	25	surgery	surgery	NN
cord-010027-r0tl01kq	849	26	.	.	.
cord-010027-r0tl01kq	850	1	Thirty	thirty	CD
cord-010027-r0tl01kq	850	2	one	one	CD
cord-010027-r0tl01kq	850	3	patients	patient	NNS
cord-010027-r0tl01kq	850	4	were	be	VBD
cord-010027-r0tl01kq	850	5	recruited	recruit	VBN
cord-010027-r0tl01kq	850	6	from	from	IN
cord-010027-r0tl01kq	850	7	seven	seven	CD
cord-010027-r0tl01kq	850	8	UK	UK	NNP
cord-010027-r0tl01kq	850	9	centres	centre	NNS
cord-010027-r0tl01kq	850	10	between	between	IN
cord-010027-r0tl01kq	850	11	June	June	NNP
cord-010027-r0tl01kq	850	12	2012	2012	CD
cord-010027-r0tl01kq	850	13	and	and	CC
cord-010027-r0tl01kq	850	14	May	May	NNP
cord-010027-r0tl01kq	850	15	2014	2014	CD
cord-010027-r0tl01kq	850	16	.	.	.
cord-010027-r0tl01kq	851	1	Photographs	photograph	NNS
cord-010027-r0tl01kq	851	2	were	be	VBD
cord-010027-r0tl01kq	851	3	taken	take	VBN
cord-010027-r0tl01kq	851	4	of	of	IN
cord-010027-r0tl01kq	851	5	the	the	DT
cord-010027-r0tl01kq	851	6	specimens	specimen	NNS
cord-010027-r0tl01kq	851	7	and	and	CC
cord-010027-r0tl01kq	851	8	assessed	assess	VBN
cord-010027-r0tl01kq	851	9	by	by	IN
cord-010027-r0tl01kq	851	10	a	a	DT
cord-010027-r0tl01kq	851	11	blinded	blinded	JJ
cord-010027-r0tl01kq	851	12	histopathologist	histopathologist	NN
cord-010027-r0tl01kq	851	13	for	for	IN
cord-010027-r0tl01kq	851	14	the	the	DT
cord-010027-r0tl01kq	851	15	quality	quality	NN
cord-010027-r0tl01kq	851	16	of	of	IN
cord-010027-r0tl01kq	851	17	the	the	DT
cord-010027-r0tl01kq	851	18	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	851	19	dissection	dissection	NN
cord-010027-r0tl01kq	851	20	.	.	.
cord-010027-r0tl01kq	852	1	Rates	rate	NNS
cord-010027-r0tl01kq	852	2	of	of	IN
cord-010027-r0tl01kq	852	3	pathological	pathological	JJ
cord-010027-r0tl01kq	852	4	complete	complete	JJ
cord-010027-r0tl01kq	852	5	response	response	NN
cord-010027-r0tl01kq	852	6	(	(	-LRB-
cord-010027-r0tl01kq	852	7	pCR	pCR	NNP
cord-010027-r0tl01kq	852	8	)	)	-RRB-
cord-010027-r0tl01kq	852	9	,	,	,
cord-010027-r0tl01kq	852	10	down	down	RB
cord-010027-r0tl01kq	852	11	-	-	HYPH
cord-010027-r0tl01kq	852	12	staging	staging	NN
cord-010027-r0tl01kq	852	13	,	,	,
cord-010027-r0tl01kq	852	14	and	and	CC
cord-010027-r0tl01kq	852	15	circumferential	circumferential	JJ
cord-010027-r0tl01kq	852	16	resection	resection	NN
cord-010027-r0tl01kq	852	17	margin	margin	NN
cord-010027-r0tl01kq	852	18	(	(	-LRB-
cord-010027-r0tl01kq	852	19	CRM	CRM	NNP
cord-010027-r0tl01kq	852	20	)	)	-RRB-
cord-010027-r0tl01kq	852	21	involvement	involvement	NN
cord-010027-r0tl01kq	852	22	were	be	VBD
cord-010027-r0tl01kq	852	23	determined	determine	VBN
cord-010027-r0tl01kq	852	24	.	.	.
cord-010027-r0tl01kq	853	1	Response	response	NN
cord-010027-r0tl01kq	853	2	was	be	VBD
cord-010027-r0tl01kq	853	3	also	also	RB
cord-010027-r0tl01kq	853	4	assessed	assess	VBN
cord-010027-r0tl01kq	853	5	using	use	VBG
cord-010027-r0tl01kq	853	6	novel	novel	JJ
cord-010027-r0tl01kq	853	7	tumour	tumour	NN
cord-010027-r0tl01kq	853	8	cell	cell	NN
cord-010027-r0tl01kq	853	9	density	density	NN
cord-010027-r0tl01kq	853	10	(	(	-LRB-
cord-010027-r0tl01kq	853	11	TCD	TCD	NNP
cord-010027-r0tl01kq	853	12	)	)	-RRB-
cord-010027-r0tl01kq	853	13	assessment	assessment	NN
cord-010027-r0tl01kq	853	14	where	where	WRB
cord-010027-r0tl01kq	853	15	the	the	DT
cord-010027-r0tl01kq	853	16	slides	slide	NNS
cord-010027-r0tl01kq	853	17	from	from	IN
cord-010027-r0tl01kq	853	18	the	the	DT
cord-010027-r0tl01kq	853	19	resected	resected	JJ
cord-010027-r0tl01kq	853	20	specimen	specimen	JJ
cord-010027-r0tl01kq	853	21	and	and	CC
cord-010027-r0tl01kq	853	22	baseline	baseline	JJ
cord-010027-r0tl01kq	853	23	biopsy	biopsy	NN
cord-010027-r0tl01kq	853	24	were	be	VBD
cord-010027-r0tl01kq	853	25	scanned	scan	VBN
cord-010027-r0tl01kq	853	26	at	at	IN
cord-010027-r0tl01kq	853	27	400x	400x	CD
cord-010027-r0tl01kq	853	28	magnification	magnification	NN
cord-010027-r0tl01kq	853	29	,	,	,
cord-010027-r0tl01kq	853	30	the	the	DT
cord-010027-r0tl01kq	853	31	tumour	tumour	NN
cord-010027-r0tl01kq	853	32	area	area	NN
cord-010027-r0tl01kq	853	33	selected	select	VBN
cord-010027-r0tl01kq	853	34	and	and	CC
cord-010027-r0tl01kq	853	35	285	285	CD
cord-010027-r0tl01kq	853	36	to	to	TO
cord-010027-r0tl01kq	853	37	315	315	CD
cord-010027-r0tl01kq	853	38	data	data	NN
cord-010027-r0tl01kq	853	39	-	-	HYPH
cord-010027-r0tl01kq	853	40	points	point	NNS
cord-010027-r0tl01kq	853	41	analysed	analyse	VBN
cord-010027-r0tl01kq	853	42	by	by	IN
cord-010027-r0tl01kq	853	43	a	a	DT
cord-010027-r0tl01kq	853	44	blinded	blind	VBN
cord-010027-r0tl01kq	853	45	expert	expert	NN
cord-010027-r0tl01kq	853	46	to	to	TO
cord-010027-r0tl01kq	853	47	describe	describe	VB
cord-010027-r0tl01kq	853	48	the	the	DT
cord-010027-r0tl01kq	853	49	percentage	percentage	NN
cord-010027-r0tl01kq	853	50	of	of	IN
cord-010027-r0tl01kq	853	51	different	different	JJ
cord-010027-r0tl01kq	853	52	tissue	tissue	NN
cord-010027-r0tl01kq	853	53	components	component	NNS
cord-010027-r0tl01kq	853	54	.	.	.
cord-010027-r0tl01kq	854	1	The	the	DT
cord-010027-r0tl01kq	854	2	work	work	NN
cord-010027-r0tl01kq	854	3	was	be	VBD
cord-010027-r0tl01kq	854	4	partly	partly	RB
cord-010027-r0tl01kq	854	5	funded	fund	VBN
cord-010027-r0tl01kq	854	6	by	by	IN
cord-010027-r0tl01kq	854	7	a	a	DT
cord-010027-r0tl01kq	854	8	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	854	9	Career	Career	NNP
cord-010027-r0tl01kq	854	10	Development	Development	NNP
cord-010027-r0tl01kq	854	11	Fellowship	Fellowship	NNP
cord-010027-r0tl01kq	854	12	and	and	CC
cord-010027-r0tl01kq	854	13	is	be	VBZ
cord-010027-r0tl01kq	854	14	presented	present	VBN
cord-010027-r0tl01kq	854	15	on	on	IN
cord-010027-r0tl01kq	854	16	behalf	behalf	NN
cord-010027-r0tl01kq	854	17	of	of	IN
cord-010027-r0tl01kq	854	18	the	the	DT
cord-010027-r0tl01kq	854	19	STARRCAT	STARRCAT	NNP
cord-010027-r0tl01kq	854	20	Trial	Trial	NNP
cord-010027-r0tl01kq	854	21	Investigators	Investigators	NNPS
cord-010027-r0tl01kq	854	22	.	.	.
cord-010027-r0tl01kq	855	1	Twenty	twenty	CD
cord-010027-r0tl01kq	855	2	three	three	CD
cord-010027-r0tl01kq	855	3	patients	patient	NNS
cord-010027-r0tl01kq	855	4	underwent	undergo	VBD
cord-010027-r0tl01kq	855	5	surgery	surgery	NN
cord-010027-r0tl01kq	855	6	(	(	-LRB-
cord-010027-r0tl01kq	855	7	10	10	CD
cord-010027-r0tl01kq	855	8	from	from	IN
cord-010027-r0tl01kq	855	9	the	the	DT
cord-010027-r0tl01kq	855	10	6-week	6-week	JJ
cord-010027-r0tl01kq	855	11	arm	arm	NN
cord-010027-r0tl01kq	855	12	and	and	CC
cord-010027-r0tl01kq	855	13	13	13	CD
cord-010027-r0tl01kq	855	14	from	from	IN
cord-010027-r0tl01kq	855	15	the	the	DT
cord-010027-r0tl01kq	855	16	12-week	12-week	JJ
cord-010027-r0tl01kq	855	17	arm	arm	NN
cord-010027-r0tl01kq	855	18	)	)	-RRB-
cord-010027-r0tl01kq	855	19	.	.	.
cord-010027-r0tl01kq	856	1	The	the	DT
cord-010027-r0tl01kq	856	2	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	856	3	fascial	fascial	JJ
cord-010027-r0tl01kq	856	4	plane	plane	NN
cord-010027-r0tl01kq	856	5	was	be	VBD
cord-010027-r0tl01kq	856	6	intact	intact	JJ
cord-010027-r0tl01kq	856	7	in	in	IN
cord-010027-r0tl01kq	856	8	7	7	CD
cord-010027-r0tl01kq	856	9	specimens	specimen	NNS
cord-010027-r0tl01kq	856	10	from	from	IN
cord-010027-r0tl01kq	856	11	the	the	DT
cord-010027-r0tl01kq	856	12	6-week	6-week	JJ
cord-010027-r0tl01kq	856	13	arm	arm	NN
cord-010027-r0tl01kq	856	14	(	(	-LRB-
cord-010027-r0tl01kq	856	15	70	70	CD
cord-010027-r0tl01kq	856	16	%	%	NN
cord-010027-r0tl01kq	856	17	)	)	-RRB-
cord-010027-r0tl01kq	856	18	and	and	CC
cord-010027-r0tl01kq	856	19	8	8	CD
cord-010027-r0tl01kq	856	20	from	from	IN
cord-010027-r0tl01kq	856	21	the	the	DT
cord-010027-r0tl01kq	856	22	12-week	12-week	JJ
cord-010027-r0tl01kq	856	23	arm	arm	NN
cord-010027-r0tl01kq	856	24	(	(	-LRB-
cord-010027-r0tl01kq	856	25	62	62	CD
cord-010027-r0tl01kq	856	26	%	%	NN
cord-010027-r0tl01kq	856	27	)	)	-RRB-
cord-010027-r0tl01kq	856	28	.	.	.
cord-010027-r0tl01kq	857	1	Three	three	CD
cord-010027-r0tl01kq	857	2	patients	patient	NNS
cord-010027-r0tl01kq	857	3	at	at	IN
cord-010027-r0tl01kq	857	4	6-weeks	6-weeks	CD
cord-010027-r0tl01kq	857	5	and	and	CC
cord-010027-r0tl01kq	857	6	two	two	CD
cord-010027-r0tl01kq	857	7	patients	patient	NNS
cord-010027-r0tl01kq	857	8	at	at	IN
cord-010027-r0tl01kq	857	9	12-weeks	12-weeks	CD
cord-010027-r0tl01kq	857	10	showed	show	VBD
cord-010027-r0tl01kq	857	11	a	a	DT
cord-010027-r0tl01kq	857	12	pCR	pcr	NN
cord-010027-r0tl01kq	857	13	.	.	.
cord-010027-r0tl01kq	858	1	Only	only	RB
cord-010027-r0tl01kq	858	2	one	one	CD
cord-010027-r0tl01kq	858	3	patient	patient	NN
cord-010027-r0tl01kq	858	4	(	(	-LRB-
cord-010027-r0tl01kq	858	5	from	from	IN
cord-010027-r0tl01kq	858	6	the	the	DT
cord-010027-r0tl01kq	858	7	12-week	12-week	JJ
cord-010027-r0tl01kq	858	8	arm	arm	NN
cord-010027-r0tl01kq	858	9	)	)	-RRB-
cord-010027-r0tl01kq	858	10	had	have	VBD
cord-010027-r0tl01kq	858	11	an	an	DT
cord-010027-r0tl01kq	858	12	involved	involved	JJ
cord-010027-r0tl01kq	858	13	CRM	crm	NN
cord-010027-r0tl01kq	858	14	.	.	.
cord-010027-r0tl01kq	859	1	TCD	TCD	NNP
cord-010027-r0tl01kq	859	2	was	be	VBD
cord-010027-r0tl01kq	859	3	0.3	0.3	CD
cord-010027-r0tl01kq	859	4	%	%	NN
cord-010027-r0tl01kq	859	5	for	for	IN
cord-010027-r0tl01kq	859	6	the	the	DT
cord-010027-r0tl01kq	859	7	6-week	6-week	JJ
cord-010027-r0tl01kq	859	8	arm	arm	NN
cord-010027-r0tl01kq	859	9	and	and	CC
cord-010027-r0tl01kq	859	10	4.3	4.3	CD
cord-010027-r0tl01kq	859	11	%	%	NN
cord-010027-r0tl01kq	859	12	for	for	IN
cord-010027-r0tl01kq	859	13	the	the	DT
cord-010027-r0tl01kq	859	14	12	12	CD
cord-010027-r0tl01kq	859	15	week	week	NN
cord-010027-r0tl01kq	859	16	arm	arm	NN
cord-010027-r0tl01kq	859	17	(	(	-LRB-
cord-010027-r0tl01kq	859	18	p=0.12	p=0.12	NN
cord-010027-r0tl01kq	859	19	)	)	-RRB-
cord-010027-r0tl01kq	859	20	.	.	.
cord-010027-r0tl01kq	860	1	In	in	IN
cord-010027-r0tl01kq	860	2	this	this	DT
cord-010027-r0tl01kq	860	3	small	small	JJ
cord-010027-r0tl01kq	860	4	randomised	randomised	JJ
cord-010027-r0tl01kq	860	5	trial	trial	NN
cord-010027-r0tl01kq	860	6	,	,	,
cord-010027-r0tl01kq	860	7	rates	rate	NNS
cord-010027-r0tl01kq	860	8	of	of	IN
cord-010027-r0tl01kq	860	9	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	860	10	quality	quality	NN
cord-010027-r0tl01kq	860	11	,	,	,
cord-010027-r0tl01kq	860	12	CRM	CRM	NNP
cord-010027-r0tl01kq	860	13	status	status	NN
cord-010027-r0tl01kq	860	14	,	,	,
cord-010027-r0tl01kq	860	15	pCR	pCR	NNP
cord-010027-r0tl01kq	860	16	and	and	CC
cord-010027-r0tl01kq	860	17	TCD	TCD	NNP
cord-010027-r0tl01kq	860	18	were	be	VBD
cord-010027-r0tl01kq	860	19	similar	similar	JJ
cord-010027-r0tl01kq	860	20	following	follow	VBG
cord-010027-r0tl01kq	860	21	either	either	CC
cord-010027-r0tl01kq	860	22	a	a	DT
cord-010027-r0tl01kq	860	23	6	6	CD
cord-010027-r0tl01kq	860	24	or	or	CC
cord-010027-r0tl01kq	860	25	12	12	CD
cord-010027-r0tl01kq	860	26	week	week	NN
cord-010027-r0tl01kq	860	27	interval	interval	NN
cord-010027-r0tl01kq	860	28	after	after	IN
cord-010027-r0tl01kq	860	29	CRT	CRT	NNP
cord-010027-r0tl01kq	860	30	.	.	.
cord-010027-r0tl01kq	861	1	Further	further	JJ
cord-010027-r0tl01kq	861	2	studies	study	NNS
cord-010027-r0tl01kq	861	3	are	be	VBP
cord-010027-r0tl01kq	861	4	now	now	RB
cord-010027-r0tl01kq	861	5	needed	need	VBN
cord-010027-r0tl01kq	861	6	to	to	TO
cord-010027-r0tl01kq	861	7	clarify	clarify	VB
cord-010027-r0tl01kq	861	8	whether	whether	IN
cord-010027-r0tl01kq	861	9	a	a	DT
cord-010027-r0tl01kq	861	10	longer	long	JJR
cord-010027-r0tl01kq	861	11	interval	interval	NN
cord-010027-r0tl01kq	861	12	does	do	VBZ
cord-010027-r0tl01kq	861	13	facilitate	facilitate	VB
cord-010027-r0tl01kq	861	14	on	on	IN
cord-010027-r0tl01kq	861	15	going	go	VBG
cord-010027-r0tl01kq	861	16	down	down	RB
cord-010027-r0tl01kq	861	17	-	-	HYPH
cord-010027-r0tl01kq	861	18	staging	staging	NN
cord-010027-r0tl01kq	861	19	.	.	.
cord-010027-r0tl01kq	862	1	The	the	DT
cord-010027-r0tl01kq	862	2	Role	role	NN
cord-010027-r0tl01kq	862	3	of	of	IN
cord-010027-r0tl01kq	862	4	Tissue	Tissue	NNP
cord-010027-r0tl01kq	862	5	Factor	Factor	NNP
cord-010027-r0tl01kq	862	6	Pathway	Pathway	NNP
cord-010027-r0tl01kq	862	7	Inhibitor	Inhibitor	NNP
cord-010027-r0tl01kq	862	8	(	(	-LRB-
cord-010027-r0tl01kq	862	9	TFPI	TFPI	NNP
cord-010027-r0tl01kq	862	10	)	)	-RRB-
cord-010027-r0tl01kq	862	11	in	in	IN
cord-010027-r0tl01kq	862	12	Liver	Liver	NNP
cord-010027-r0tl01kq	862	13	Injury	Injury	NNP
cord-010027-r0tl01kq	862	14	P	p	NN
cord-010027-r0tl01kq	862	15	G	G	NNP
cord-010027-r0tl01kq	862	16	Petts	Petts	NNP
cord-010027-r0tl01kq	862	17	1	1	CD
cord-010027-r0tl01kq	862	18	;	;	:
cord-010027-r0tl01kq	862	19	H	H	NNP
cord-010027-r0tl01kq	862	20	Kudo	Kudo	NNP
cord-010027-r0tl01kq	862	21	1	1	CD
cord-010027-r0tl01kq	862	22	;	;	:
cord-010027-r0tl01kq	862	23	A	a	DT
cord-010027-r0tl01kq	862	24	Dorling	Dorling	NNP
cord-010027-r0tl01kq	862	25	2	2	CD
cord-010027-r0tl01kq	862	26	;	;	:
cord-010027-r0tl01kq	862	27	M	M	NNP
cord-010027-r0tl01kq	862	28	Thursz	Thursz	NNP
cord-010027-r0tl01kq	862	29	1	1	CD
cord-010027-r0tl01kq	862	30	;	;	:
cord-010027-r0tl01kq	862	31	R	R	NNP
cord-010027-r0tl01kq	862	32	Goldin	Goldin	NNP
cord-010027-r0tl01kq	862	33	1	1	CD
cord-010027-r0tl01kq	862	34	1	1	CD
cord-010027-r0tl01kq	862	35	Imperial	Imperial	NNP
cord-010027-r0tl01kq	862	36	College	College	NNP
cord-010027-r0tl01kq	862	37	London	London	NNP
cord-010027-r0tl01kq	862	38	,	,	,
cord-010027-r0tl01kq	862	39	London	London	NNP
cord-010027-r0tl01kq	862	40	,	,	,
cord-010027-r0tl01kq	862	41	UK	UK	NNP
cord-010027-r0tl01kq	862	42	;	;	:
cord-010027-r0tl01kq	862	43	2	2	CD
cord-010027-r0tl01kq	862	44	Kings	Kings	NNPS
cord-010027-r0tl01kq	862	45	College	College	NNP
cord-010027-r0tl01kq	862	46	London	London	NNP
cord-010027-r0tl01kq	862	47	,	,	,
cord-010027-r0tl01kq	862	48	London	London	NNP
cord-010027-r0tl01kq	862	49	,	,	,
cord-010027-r0tl01kq	863	1	UK	UK	NNP
cord-010027-r0tl01kq	863	2	Introduction	introduction	NN
cord-010027-r0tl01kq	863	3	:	:	:
cord-010027-r0tl01kq	863	4	Studies	study	NNS
cord-010027-r0tl01kq	863	5	have	have	VBP
cord-010027-r0tl01kq	863	6	demonstrated	demonstrate	VBN
cord-010027-r0tl01kq	863	7	that	that	IN
cord-010027-r0tl01kq	863	8	inhibition	inhibition	NN
cord-010027-r0tl01kq	863	9	of	of	IN
cord-010027-r0tl01kq	863	10	the	the	DT
cord-010027-r0tl01kq	863	11	coagulant	coagulant	NN
cord-010027-r0tl01kq	863	12	cascade	cascade	NN
cord-010027-r0tl01kq	863	13	is	be	VBZ
cord-010027-r0tl01kq	863	14	associated	associate	VBN
cord-010027-r0tl01kq	863	15	with	with	IN
cord-010027-r0tl01kq	863	16	less	less	RBR
cord-010027-r0tl01kq	863	17	advanced	advanced	JJ
cord-010027-r0tl01kq	863	18	liver	liver	NN
cord-010027-r0tl01kq	863	19	fibrosis	fibrosis	NN
cord-010027-r0tl01kq	863	20	and	and	CC
cord-010027-r0tl01kq	863	21	better	well	JJR
cord-010027-r0tl01kq	863	22	outcome	outcome	NN
cord-010027-r0tl01kq	863	23	in	in	IN
cord-010027-r0tl01kq	863	24	acute	acute	JJ
cord-010027-r0tl01kq	863	25	liver	liver	NN
cord-010027-r0tl01kq	863	26	injury	injury	NN
cord-010027-r0tl01kq	863	27	.	.	.
cord-010027-r0tl01kq	864	1	TFPI	TFPI	NNP
cord-010027-r0tl01kq	864	2	is	be	VBZ
cord-010027-r0tl01kq	864	3	a	a	DT
cord-010027-r0tl01kq	864	4	serine	serine	JJ
cord-010027-r0tl01kq	864	5	protease	protease	NN
cord-010027-r0tl01kq	864	6	inhibitor	inhibitor	NN
cord-010027-r0tl01kq	864	7	that	that	WDT
cord-010027-r0tl01kq	864	8	acts	act	VBZ
cord-010027-r0tl01kq	864	9	as	as	IN
cord-010027-r0tl01kq	864	10	a	a	DT
cord-010027-r0tl01kq	864	11	homeostatic	homeostatic	JJ
cord-010027-r0tl01kq	864	12	inhibitor	inhibitor	NN
cord-010027-r0tl01kq	864	13	of	of	IN
cord-010027-r0tl01kq	864	14	the	the	DT
cord-010027-r0tl01kq	864	15	coagulation	coagulation	NN
cord-010027-r0tl01kq	864	16	cascade	cascade	NN
cord-010027-r0tl01kq	864	17	and	and	CC
cord-010027-r0tl01kq	864	18	may	may	MD
cord-010027-r0tl01kq	864	19	be	be	VB
cord-010027-r0tl01kq	864	20	a	a	DT
cord-010027-r0tl01kq	864	21	target	target	NN
cord-010027-r0tl01kq	864	22	to	to	TO
cord-010027-r0tl01kq	864	23	modify	modify	VB
cord-010027-r0tl01kq	864	24	outcome	outcome	NN
cord-010027-r0tl01kq	864	25	in	in	IN
cord-010027-r0tl01kq	864	26	liver	liver	NN
cord-010027-r0tl01kq	864	27	disease	disease	NN
cord-010027-r0tl01kq	864	28	.	.	.
cord-010027-r0tl01kq	865	1	Methods	method	NNS
cord-010027-r0tl01kq	865	2	:	:	:
cord-010027-r0tl01kq	865	3	Transgenic	transgenic	JJ
cord-010027-r0tl01kq	865	4	mice	mouse	NNS
cord-010027-r0tl01kq	865	5	carrying	carry	VBG
cord-010027-r0tl01kq	865	6	a	a	DT
cord-010027-r0tl01kq	865	7	genetic	genetic	JJ
cord-010027-r0tl01kq	865	8	modification	modification	NN
cord-010027-r0tl01kq	865	9	that	that	WDT
cord-010027-r0tl01kq	865	10	allows	allow	VBZ
cord-010027-r0tl01kq	865	11	cells	cell	NNS
cord-010027-r0tl01kq	865	12	expressing	express	VBG
cord-010027-r0tl01kq	865	13	a	a	DT
cord-010027-r0tl01kq	865	14	-	-	HYPH
cord-010027-r0tl01kq	865	15	smooth	smooth	JJ
cord-010027-r0tl01kq	865	16	muscle	muscle	NN
cord-010027-r0tl01kq	865	17	actin	actin	NN
cord-010027-r0tl01kq	865	18	(	(	-LRB-
cord-010027-r0tl01kq	865	19	aSMA	aSMA	NNP
cord-010027-r0tl01kq	865	20	;	;	:
cord-010027-r0tl01kq	865	21	e.g.	e.g.	RB
cord-010027-r0tl01kq	865	22	activated	activate	VBN
cord-010027-r0tl01kq	865	23	hepatic	hepatic	JJ
cord-010027-r0tl01kq	865	24	stellate	stellate	JJ
cord-010027-r0tl01kq	865	25	cells	cell	NNS
cord-010027-r0tl01kq	865	26	)	)	-RRB-
cord-010027-r0tl01kq	866	1	to	to	TO
cord-010027-r0tl01kq	866	2	simultaneously	simultaneously	RB
cord-010027-r0tl01kq	866	3	express	express	VB
cord-010027-r0tl01kq	866	4	TFPI	TFPI	NNP
cord-010027-r0tl01kq	866	5	were	be	VBD
cord-010027-r0tl01kq	866	6	used	use	VBN
cord-010027-r0tl01kq	866	7	in	in	IN
cord-010027-r0tl01kq	866	8	models	model	NNS
cord-010027-r0tl01kq	866	9	of	of	IN
cord-010027-r0tl01kq	866	10	chronic	chronic	JJ
cord-010027-r0tl01kq	866	11	liver	liver	NN
cord-010027-r0tl01kq	866	12	injury	injury	NN
cord-010027-r0tl01kq	866	13	(	(	-LRB-
cord-010027-r0tl01kq	866	14	carbon	carbon	NN
cord-010027-r0tl01kq	866	15	tetrachloride	tetrachloride	NN
cord-010027-r0tl01kq	866	16	,	,	,
cord-010027-r0tl01kq	866	17	CCl4	ccl4	NN
cord-010027-r0tl01kq	866	18	)	)	-RRB-
cord-010027-r0tl01kq	866	19	or	or	CC
cord-010027-r0tl01kq	866	20	acute	acute	JJ
cord-010027-r0tl01kq	866	21	liver	liver	NN
cord-010027-r0tl01kq	866	22	injury	injury	NN
cord-010027-r0tl01kq	866	23	(	(	-LRB-
cord-010027-r0tl01kq	866	24	paracetamol	paracetamol	NNP
cord-010027-r0tl01kq	866	25	)	)	-RRB-
cord-010027-r0tl01kq	866	26	and	and	CC
cord-010027-r0tl01kq	866	27	culled	cull	VBN
cord-010027-r0tl01kq	866	28	at	at	IN
cord-010027-r0tl01kq	866	29	set	set	VBN
cord-010027-r0tl01kq	866	30	time	time	NN
cord-010027-r0tl01kq	866	31	points	point	NNS
cord-010027-r0tl01kq	866	32	after	after	IN
cord-010027-r0tl01kq	866	33	dosing	dose	VBG
cord-010027-r0tl01kq	866	34	.	.	.
cord-010027-r0tl01kq	867	1	Results	result	NNS
cord-010027-r0tl01kq	867	2	:	:	:
cord-010027-r0tl01kq	867	3	Chronic	chronic	JJ
cord-010027-r0tl01kq	867	4	liver	liver	NN
cord-010027-r0tl01kq	867	5	injury	injury	NN
cord-010027-r0tl01kq	867	6	:	:	:
cord-010027-r0tl01kq	868	1	At	at	IN
cord-010027-r0tl01kq	868	2	24	24	CD
cord-010027-r0tl01kq	868	3	hours	hour	NNS
cord-010027-r0tl01kq	868	4	after	after	IN
cord-010027-r0tl01kq	868	5	the	the	DT
cord-010027-r0tl01kq	868	6	last	last	JJ
cord-010027-r0tl01kq	868	7	dose	dose	NN
cord-010027-r0tl01kq	868	8	of	of	IN
cord-010027-r0tl01kq	868	9	CCl4	ccl4	NN
cord-010027-r0tl01kq	868	10	the	the	DT
cord-010027-r0tl01kq	868	11	transgenic	transgenic	JJ
cord-010027-r0tl01kq	868	12	mice	mouse	NNS
cord-010027-r0tl01kq	868	13	had	have	VBD
cord-010027-r0tl01kq	868	14	significantly	significantly	RB
cord-010027-r0tl01kq	868	15	decreased	decrease	VBN
cord-010027-r0tl01kq	868	16	aSMA	asma	JJ
cord-010027-r0tl01kq	868	17	expression	expression	NN
cord-010027-r0tl01kq	868	18	and	and	CC
cord-010027-r0tl01kq	868	19	tissue	tissue	NN
cord-010027-r0tl01kq	868	20	inhibitor	inhibitor	NN
cord-010027-r0tl01kq	868	21	of	of	IN
cord-010027-r0tl01kq	868	22	metalloproteinase	metalloproteinase	NN
cord-010027-r0tl01kq	868	23	(	(	-LRB-
cord-010027-r0tl01kq	868	24	TIMP	TIMP	NNP
cord-010027-r0tl01kq	868	25	)	)	-RRB-
cord-010027-r0tl01kq	869	1	-1	-1	.
cord-010027-r0tl01kq	870	1	gene	gene	NN
cord-010027-r0tl01kq	870	2	expression	expression	NN
cord-010027-r0tl01kq	870	3	but	but	CC
cord-010027-r0tl01kq	870	4	no	no	DT
cord-010027-r0tl01kq	870	5	difference	difference	NN
cord-010027-r0tl01kq	870	6	in	in	IN
cord-010027-r0tl01kq	870	7	matrix	matrix	NN
cord-010027-r0tl01kq	870	8	metalloproteinase	metalloproteinase	NN
cord-010027-r0tl01kq	870	9	(	(	-LRB-
cord-010027-r0tl01kq	870	10	MMP	MMP	NNP
cord-010027-r0tl01kq	870	11	)	)	-RRB-
cord-010027-r0tl01kq	870	12	-2	-2	XX
cord-010027-r0tl01kq	870	13	and	and	CC
cord-010027-r0tl01kq	870	14	-9	-9	NN
cord-010027-r0tl01kq	870	15	gene	gene	NN
cord-010027-r0tl01kq	870	16	expression	expression	NN
cord-010027-r0tl01kq	870	17	compared	compare	VBN
cord-010027-r0tl01kq	870	18	to	to	IN
cord-010027-r0tl01kq	870	19	wild	wild	JJ
cord-010027-r0tl01kq	870	20	types	type	NNS
cord-010027-r0tl01kq	870	21	.	.	.
cord-010027-r0tl01kq	871	1	This	this	DT
cord-010027-r0tl01kq	871	2	suggested	suggest	VBD
cord-010027-r0tl01kq	871	3	a	a	DT
cord-010027-r0tl01kq	871	4	microenvironment	microenvironment	NN
cord-010027-r0tl01kq	871	5	that	that	WDT
cord-010027-r0tl01kq	871	6	would	would	MD
cord-010027-r0tl01kq	871	7	promote	promote	VB
cord-010027-r0tl01kq	871	8	fibrosis	fibrosis	NN
cord-010027-r0tl01kq	871	9	resolution	resolution	NN
cord-010027-r0tl01kq	871	10	.	.	.
cord-010027-r0tl01kq	872	1	However	however	RB
cord-010027-r0tl01kq	872	2	after	after	IN
cord-010027-r0tl01kq	872	3	24	24	CD
cord-010027-r0tl01kq	872	4	hours	hour	NNS
cord-010027-r0tl01kq	872	5	this	this	DT
cord-010027-r0tl01kq	872	6	difference	difference	NN
cord-010027-r0tl01kq	872	7	was	be	VBD
cord-010027-r0tl01kq	872	8	lost	lose	VBN
cord-010027-r0tl01kq	872	9	.	.	.
cord-010027-r0tl01kq	873	1	At	at	RB
cord-010027-r0tl01kq	873	2	all	all	DT
cord-010027-r0tl01kq	873	3	time	time	NN
cord-010027-r0tl01kq	873	4	points	point	NNS
cord-010027-r0tl01kq	873	5	there	there	EX
cord-010027-r0tl01kq	873	6	was	be	VBD
cord-010027-r0tl01kq	873	7	no	no	DT
cord-010027-r0tl01kq	873	8	significant	significant	JJ
cord-010027-r0tl01kq	873	9	difference	difference	NN
cord-010027-r0tl01kq	873	10	between	between	IN
cord-010027-r0tl01kq	873	11	fibrosis	fibrosis	NN
cord-010027-r0tl01kq	873	12	in	in	IN
cord-010027-r0tl01kq	873	13	transgenic	transgenic	JJ
cord-010027-r0tl01kq	873	14	and	and	CC
cord-010027-r0tl01kq	873	15	wild	wild	JJ
cord-010027-r0tl01kq	873	16	type	type	NN
cord-010027-r0tl01kq	873	17	mice	mouse	NNS
cord-010027-r0tl01kq	873	18	as	as	IN
cord-010027-r0tl01kq	873	19	demonstrated	demonstrate	VBN
cord-010027-r0tl01kq	873	20	by	by	IN
cord-010027-r0tl01kq	873	21	Sirius	Sirius	NNP
cord-010027-r0tl01kq	873	22	red	red	JJ
cord-010027-r0tl01kq	873	23	staining	staining	NN
cord-010027-r0tl01kq	873	24	,	,	,
cord-010027-r0tl01kq	873	25	hydroxyproline	hydroxyproline	NN
cord-010027-r0tl01kq	873	26	assay	assay	NN
cord-010027-r0tl01kq	873	27	and	and	CC
cord-010027-r0tl01kq	873	28	collagen	collagen	NN
cord-010027-r0tl01kq	873	29	1a1	1a1	CD
cord-010027-r0tl01kq	873	30	gene	gene	NN
cord-010027-r0tl01kq	873	31	expression	expression	NN
cord-010027-r0tl01kq	873	32	.	.	.
cord-010027-r0tl01kq	874	1	Acute	acute	JJ
cord-010027-r0tl01kq	874	2	liver	liver	NN
cord-010027-r0tl01kq	874	3	injury	injury	NN
cord-010027-r0tl01kq	874	4	:	:	:
cord-010027-r0tl01kq	875	1	In	in	IN
cord-010027-r0tl01kq	875	2	paracetamol	paracetamol	NNP
cord-010027-r0tl01kq	875	3	induced	induce	VBD
cord-010027-r0tl01kq	875	4	liver	liver	NN
cord-010027-r0tl01kq	875	5	injury	injury	NN
cord-010027-r0tl01kq	875	6	there	there	EX
cord-010027-r0tl01kq	875	7	was	be	VBD
cord-010027-r0tl01kq	875	8	a	a	DT
cord-010027-r0tl01kq	875	9	significant	significant	JJ
cord-010027-r0tl01kq	875	10	difference	difference	NN
cord-010027-r0tl01kq	875	11	in	in	IN
cord-010027-r0tl01kq	875	12	parenchymal	parenchymal	JJ
cord-010027-r0tl01kq	875	13	necrosis	necrosis	NN
cord-010027-r0tl01kq	875	14	in	in	IN
cord-010027-r0tl01kq	875	15	transgenic	transgenic	JJ
cord-010027-r0tl01kq	875	16	mice	mouse	NNS
cord-010027-r0tl01kq	875	17	compared	compare	VBN
cord-010027-r0tl01kq	875	18	to	to	IN
cord-010027-r0tl01kq	875	19	wild	wild	JJ
cord-010027-r0tl01kq	875	20	types	type	NNS
cord-010027-r0tl01kq	875	21	at	at	IN
cord-010027-r0tl01kq	875	22	24	24	CD
cord-010027-r0tl01kq	875	23	and	and	CC
cord-010027-r0tl01kq	875	24	48	48	CD
cord-010027-r0tl01kq	875	25	hours	hour	NNS
cord-010027-r0tl01kq	875	26	after	after	IN
cord-010027-r0tl01kq	875	27	dosing	dose	VBG
cord-010027-r0tl01kq	875	28	(	(	-LRB-
cord-010027-r0tl01kq	875	29	24	24	CD
cord-010027-r0tl01kq	875	30	hours	hour	NNS
cord-010027-r0tl01kq	875	31	:	:	:
cord-010027-r0tl01kq	876	1	mean	mean	VB
cord-010027-r0tl01kq	876	2	necrosis	necrosis	NN
cord-010027-r0tl01kq	876	3	6	6	CD
cord-010027-r0tl01kq	876	4	%	%	NN
cord-010027-r0tl01kq	876	5	vs.	vs.	CC
cord-010027-r0tl01kq	876	6	30	30	CD
cord-010027-r0tl01kq	876	7	%	%	NN
cord-010027-r0tl01kq	876	8	respectively	respectively	RB
cord-010027-r0tl01kq	876	9	,	,	,
cord-010027-r0tl01kq	876	10	Mann	Mann	NNP
cord-010027-r0tl01kq	876	11	-	-	HYPH
cord-010027-r0tl01kq	876	12	Whitney	Whitney	NNP
cord-010027-r0tl01kq	876	13	test	test	NN
cord-010027-r0tl01kq	876	14	p=0.008	p=0.008	NNP
cord-010027-r0tl01kq	876	15	.	.	.
cord-010027-r0tl01kq	877	1	48	48	CD
cord-010027-r0tl01kq	877	2	hours	hour	NNS
cord-010027-r0tl01kq	877	3	:	:	:
cord-010027-r0tl01kq	878	1	mean	mean	VB
cord-010027-r0tl01kq	878	2	necrosis	necrosis	NN
cord-010027-r0tl01kq	878	3	2	2	CD
cord-010027-r0tl01kq	878	4	%	%	NN
cord-010027-r0tl01kq	878	5	vs.	vs.	CC
cord-010027-r0tl01kq	878	6	20	20	CD
cord-010027-r0tl01kq	878	7	%	%	NN
cord-010027-r0tl01kq	878	8	respectively	respectively	RB
cord-010027-r0tl01kq	878	9	,	,	,
cord-010027-r0tl01kq	878	10	Mann	Mann	NNP
cord-010027-r0tl01kq	878	11	-	-	HYPH
cord-010027-r0tl01kq	878	12	Whitney	Whitney	NNP
cord-010027-r0tl01kq	878	13	test	test	NN
cord-010027-r0tl01kq	878	14	p=0.036	p=0.036	NNS
cord-010027-r0tl01kq	878	15	)	)	-RRB-
cord-010027-r0tl01kq	878	16	.	.	.
cord-010027-r0tl01kq	879	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	879	2	:	:	:
cord-010027-r0tl01kq	880	1	These	these	DT
cord-010027-r0tl01kq	880	2	results	result	NNS
cord-010027-r0tl01kq	880	3	suggest	suggest	VBP
cord-010027-r0tl01kq	880	4	that	that	IN
cord-010027-r0tl01kq	880	5	TFPI	TFPI	NNP
cord-010027-r0tl01kq	880	6	is	be	VBZ
cord-010027-r0tl01kq	880	7	an	an	DT
cord-010027-r0tl01kq	880	8	unlikely	unlikely	JJ
cord-010027-r0tl01kq	880	9	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	880	10	target	target	NN
cord-010027-r0tl01kq	880	11	in	in	IN
cord-010027-r0tl01kq	880	12	chronic	chronic	JJ
cord-010027-r0tl01kq	880	13	liver	liver	NN
cord-010027-r0tl01kq	880	14	injury	injury	NN
cord-010027-r0tl01kq	880	15	.	.	.
cord-010027-r0tl01kq	881	1	However	however	RB
cord-010027-r0tl01kq	881	2	in	in	IN
cord-010027-r0tl01kq	881	3	acute	acute	JJ
cord-010027-r0tl01kq	881	4	paracetamol	paracetamol	NN
cord-010027-r0tl01kq	881	5	induced	induce	VBD
cord-010027-r0tl01kq	881	6	liver	liver	NN
cord-010027-r0tl01kq	881	7	injury	injury	NN
cord-010027-r0tl01kq	881	8	TFPI	TFPI	NNP
cord-010027-r0tl01kq	881	9	appears	appear	VBZ
cord-010027-r0tl01kq	881	10	to	to	TO
cord-010027-r0tl01kq	881	11	rescue	rescue	VB
cord-010027-r0tl01kq	881	12	the	the	DT
cord-010027-r0tl01kq	881	13	injured	injure	VBN
cord-010027-r0tl01kq	881	14	liver	liver	NN
cord-010027-r0tl01kq	881	15	in	in	IN
cord-010027-r0tl01kq	881	16	a	a	DT
cord-010027-r0tl01kq	881	17	sustained	sustained	JJ
cord-010027-r0tl01kq	881	18	manner	manner	NN
cord-010027-r0tl01kq	881	19	from	from	IN
cord-010027-r0tl01kq	881	20	24	24	CD
cord-010027-r0tl01kq	881	21	hours	hour	NNS
cord-010027-r0tl01kq	881	22	after	after	IN
cord-010027-r0tl01kq	881	23	the	the	DT
cord-010027-r0tl01kq	881	24	initial	initial	JJ
cord-010027-r0tl01kq	881	25	insult	insult	NN
cord-010027-r0tl01kq	881	26	and	and	CC
cord-010027-r0tl01kq	881	27	suggests	suggest	VBZ
cord-010027-r0tl01kq	881	28	a	a	DT
cord-010027-r0tl01kq	881	29	role	role	NN
cord-010027-r0tl01kq	881	30	for	for	IN
cord-010027-r0tl01kq	881	31	TFPI	TFPI	NNP
cord-010027-r0tl01kq	881	32	in	in	IN
cord-010027-r0tl01kq	881	33	managing	manage	VBG
cord-010027-r0tl01kq	881	34	acute	acute	JJ
cord-010027-r0tl01kq	881	35	liver	liver	NN
cord-010027-r0tl01kq	881	36	injury	injury	NN
cord-010027-r0tl01kq	881	37	.	.	.
cord-010027-r0tl01kq	882	1	(	(	-LRB-
cord-010027-r0tl01kq	882	2	Research	research	NN
cord-010027-r0tl01kq	882	3	funded	fund	VBN
cord-010027-r0tl01kq	882	4	by	by	IN
cord-010027-r0tl01kq	882	5	the	the	DT
cord-010027-r0tl01kq	882	6	Pathological	Pathological	NNP
cord-010027-r0tl01kq	882	7	Society	Society	NNP
cord-010027-r0tl01kq	882	8	)	)	-RRB-
cord-010027-r0tl01kq	882	9	.	.	.
cord-010027-r0tl01kq	882	10	 	 	_SP
cord-010027-r0tl01kq	883	1	Analysis	analysis	NN
cord-010027-r0tl01kq	883	2	of	of	IN
cord-010027-r0tl01kq	883	3	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	883	4	and	and	CC
cord-010027-r0tl01kq	883	5	non	non	JJ
cord-010027-r0tl01kq	883	6	-	-	JJ
cord-010027-r0tl01kq	883	7	small	small	JJ
cord-010027-r0tl01kq	883	8	cell	cell	NN
cord-010027-r0tl01kq	883	9	lung	lung	NN
cord-010027-r0tl01kq	883	10	cancer	cancer	NN
cord-010027-r0tl01kq	883	11	(	(	-LRB-
cord-010027-r0tl01kq	883	12	NOS	NOS	NNP
cord-010027-r0tl01kq	883	13	)	)	-RRB-
cord-010027-r0tl01kq	883	14	for	for	IN
cord-010027-r0tl01kq	883	15	EGFR	EGFR	NNP
cord-010027-r0tl01kq	883	16	mutations	mutation	NNS
cord-010027-r0tl01kq	883	17	now	now	RB
cord-010027-r0tl01kq	883	18	forms	form	VBZ
cord-010027-r0tl01kq	883	19	part	part	NN
cord-010027-r0tl01kq	883	20	of	of	IN
cord-010027-r0tl01kq	883	21	the	the	DT
cord-010027-r0tl01kq	883	22	Royal	Royal	NNP
cord-010027-r0tl01kq	883	23	College	College	NNP
cord-010027-r0tl01kq	883	24	of	of	IN
cord-010027-r0tl01kq	883	25	Pathologists	Pathologists	NNPS
cord-010027-r0tl01kq	883	26	'	'	POS
cord-010027-r0tl01kq	883	27	lung	lung	NN
cord-010027-r0tl01kq	883	28	cancer	cancer	NN
cord-010027-r0tl01kq	883	29	dataset	dataset	NN
cord-010027-r0tl01kq	883	30	.	.	.
cord-010027-r0tl01kq	884	1	Identification	identification	NN
cord-010027-r0tl01kq	884	2	of	of	IN
cord-010027-r0tl01kq	884	3	patients	patient	NNS
cord-010027-r0tl01kq	884	4	harbouring	harbour	VBG
cord-010027-r0tl01kq	884	5	these	these	DT
cord-010027-r0tl01kq	884	6	mutations	mutation	NNS
cord-010027-r0tl01kq	884	7	facilitates	facilitate	VBZ
cord-010027-r0tl01kq	884	8	delivery	delivery	NN
cord-010027-r0tl01kq	884	9	of	of	IN
cord-010027-r0tl01kq	884	10	targeted	target	VBN
cord-010027-r0tl01kq	884	11	therapies	therapy	NNS
cord-010027-r0tl01kq	884	12	with	with	IN
cord-010027-r0tl01kq	884	13	superior	superior	JJ
cord-010027-r0tl01kq	884	14	efficacy	efficacy	NN
cord-010027-r0tl01kq	884	15	.	.	.
cord-010027-r0tl01kq	885	1	Testing	testing	NN
cord-010027-r0tl01kq	885	2	of	of	IN
cord-010027-r0tl01kq	885	3	these	these	DT
cord-010027-r0tl01kq	885	4	tumours	tumour	NNS
cord-010027-r0tl01kq	885	5	for	for	IN
cord-010027-r0tl01kq	885	6	ALK	ALK	NNP
cord-010027-r0tl01kq	885	7	has	have	VBZ
cord-010027-r0tl01kq	885	8	also	also	RB
cord-010027-r0tl01kq	885	9	been	be	VBN
cord-010027-r0tl01kq	885	10	introduced	introduce	VBN
cord-010027-r0tl01kq	885	11	in	in	IN
cord-010027-r0tl01kq	885	12	our	-PRON-	PRP$
cord-010027-r0tl01kq	885	13	centre	centre	NN
cord-010027-r0tl01kq	885	14	.	.	.
cord-010027-r0tl01kq	886	1	We	-PRON-	PRP
cord-010027-r0tl01kq	886	2	assessed	assess	VBD
cord-010027-r0tl01kq	886	3	our	-PRON-	PRP$
cord-010027-r0tl01kq	886	4	compliance	compliance	NN
cord-010027-r0tl01kq	886	5	with	with	IN
cord-010027-r0tl01kq	886	6	the	the	DT
cord-010027-r0tl01kq	886	7	College	College	NNP
cord-010027-r0tl01kq	886	8	guidelines	guideline	NNS
cord-010027-r0tl01kq	886	9	in	in	IN
cord-010027-r0tl01kq	886	10	this	this	DT
cord-010027-r0tl01kq	886	11	area	area	NN
cord-010027-r0tl01kq	886	12	for	for	IN
cord-010027-r0tl01kq	886	13	2013	2013	CD
cord-010027-r0tl01kq	886	14	and	and	CC
cord-010027-r0tl01kq	886	15	2014	2014	CD
cord-010027-r0tl01kq	886	16	.	.	.
cord-010027-r0tl01kq	887	1	In	in	IN
cord-010027-r0tl01kq	887	2	those	those	DT
cord-010027-r0tl01kq	887	3	tumours	tumour	NNS
cord-010027-r0tl01kq	887	4	positive	positive	JJ
cord-010027-r0tl01kq	887	5	for	for	IN
cord-010027-r0tl01kq	887	6	EGFR	EGFR	NNP
cord-010027-r0tl01kq	887	7	or	or	CC
cord-010027-r0tl01kq	887	8	ALK	ALK	NNP
cord-010027-r0tl01kq	887	9	mutations	mutation	NNS
cord-010027-r0tl01kq	887	10	,	,	,
cord-010027-r0tl01kq	887	11	we	-PRON-	PRP
cord-010027-r0tl01kq	887	12	examined	examine	VBD
cord-010027-r0tl01kq	887	13	the	the	DT
cord-010027-r0tl01kq	887	14	original	original	JJ
cord-010027-r0tl01kq	887	15	sections	section	NNS
cord-010027-r0tl01kq	887	16	to	to	TO
cord-010027-r0tl01kq	887	17	assess	assess	VB
cord-010027-r0tl01kq	887	18	any	any	DT
cord-010027-r0tl01kq	887	19	correlation	correlation	NN
cord-010027-r0tl01kq	887	20	between	between	IN
cord-010027-r0tl01kq	887	21	mutation	mutation	NN
cord-010027-r0tl01kq	887	22	status	status	NN
cord-010027-r0tl01kq	887	23	and	and	CC
cord-010027-r0tl01kq	887	24	morphological	morphological	JJ
cord-010027-r0tl01kq	887	25	subtype	subtype	NN
cord-010027-r0tl01kq	887	26	.	.	.
cord-010027-r0tl01kq	888	1	96	96	CD
cord-010027-r0tl01kq	888	2	of	of	IN
cord-010027-r0tl01kq	888	3	the	the	DT
cord-010027-r0tl01kq	888	4	116	116	CD
cord-010027-r0tl01kq	888	5	appropriate	appropriate	JJ
cord-010027-r0tl01kq	888	6	cases	case	NNS
cord-010027-r0tl01kq	888	7	(	(	-LRB-
cord-010027-r0tl01kq	888	8	83	83	CD
cord-010027-r0tl01kq	888	9	%	%	NN
cord-010027-r0tl01kq	888	10	)	)	-RRB-
cord-010027-r0tl01kq	888	11	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	888	12	histologically	histologically	RB
cord-010027-r0tl01kq	888	13	in	in	IN
cord-010027-r0tl01kq	888	14	2013	2013	CD
cord-010027-r0tl01kq	888	15	were	be	VBD
cord-010027-r0tl01kq	888	16	sent	send	VBN
cord-010027-r0tl01kq	888	17	for	for	IN
cord-010027-r0tl01kq	888	18	EGFR	EGFR	NNP
cord-010027-r0tl01kq	888	19	mutation	mutation	NN
cord-010027-r0tl01kq	888	20	analysis	analysis	NN
cord-010027-r0tl01kq	888	21	,	,	,
cord-010027-r0tl01kq	888	22	increasing	increase	VBG
cord-010027-r0tl01kq	888	23	to	to	IN
cord-010027-r0tl01kq	888	24	183/190	183/190	CD
cord-010027-r0tl01kq	888	25	(	(	-LRB-
cord-010027-r0tl01kq	888	26	96	96	CD
cord-010027-r0tl01kq	888	27	%	%	NN
cord-010027-r0tl01kq	888	28	)	)	-RRB-
cord-010027-r0tl01kq	888	29	in	in	IN
cord-010027-r0tl01kq	888	30	2014	2014	CD
cord-010027-r0tl01kq	888	31	.	.	.
cord-010027-r0tl01kq	889	1	20	20	CD
cord-010027-r0tl01kq	889	2	of	of	IN
cord-010027-r0tl01kq	889	3	the	the	DT
cord-010027-r0tl01kq	889	4	cases	case	NNS
cord-010027-r0tl01kq	889	5	over	over	IN
cord-010027-r0tl01kq	889	6	this	this	DT
cord-010027-r0tl01kq	889	7	time	time	NN
cord-010027-r0tl01kq	889	8	(	(	-LRB-
cord-010027-r0tl01kq	889	9	7	7	CD
cord-010027-r0tl01kq	889	10	%	%	NN
cord-010027-r0tl01kq	889	11	)	)	-RRB-
cord-010027-r0tl01kq	889	12	were	be	VBD
cord-010027-r0tl01kq	889	13	positive	positive	JJ
cord-010027-r0tl01kq	889	14	for	for	IN
cord-010027-r0tl01kq	889	15	an	an	DT
cord-010027-r0tl01kq	889	16	EGFR	EGFR	NNP
cord-010027-r0tl01kq	889	17	mutation	mutation	NN
cord-010027-r0tl01kq	889	18	.	.	.
cord-010027-r0tl01kq	890	1	Of	of	IN
cord-010027-r0tl01kq	890	2	these	these	DT
cord-010027-r0tl01kq	890	3	,	,	,
cord-010027-r0tl01kq	890	4	12	12	CD
cord-010027-r0tl01kq	890	5	showed	show	VBD
cord-010027-r0tl01kq	890	6	an	an	DT
cord-010027-r0tl01kq	890	7	acinar	acinar	JJ
cord-010027-r0tl01kq	890	8	growth	growth	NN
cord-010027-r0tl01kq	890	9	pattern	pattern	NN
cord-010027-r0tl01kq	890	10	,	,	,
cord-010027-r0tl01kq	890	11	3	3	CD
cord-010027-r0tl01kq	890	12	were	be	VBD
cord-010027-r0tl01kq	890	13	solid	solid	JJ
cord-010027-r0tl01kq	890	14	,	,	,
cord-010027-r0tl01kq	890	15	1	1	CD
cord-010027-r0tl01kq	890	16	lepidic	lepidic	NNP
cord-010027-r0tl01kq	890	17	,	,	,
cord-010027-r0tl01kq	890	18	1	1	CD
cord-010027-r0tl01kq	890	19	papillary	papillary	JJ
cord-010027-r0tl01kq	890	20	and	and	CC
cord-010027-r0tl01kq	890	21	1	1	CD
cord-010027-r0tl01kq	890	22	micropapillary	micropapillary	NN
cord-010027-r0tl01kq	890	23	.	.	.
cord-010027-r0tl01kq	891	1	It	-PRON-	PRP
cord-010027-r0tl01kq	891	2	was	be	VBD
cord-010027-r0tl01kq	891	3	not	not	RB
cord-010027-r0tl01kq	891	4	possible	possible	JJ
cord-010027-r0tl01kq	891	5	to	to	TO
cord-010027-r0tl01kq	891	6	characterise	characterise	VB
cord-010027-r0tl01kq	891	7	the	the	DT
cord-010027-r0tl01kq	891	8	growth	growth	NN
cord-010027-r0tl01kq	891	9	pattern	pattern	NN
cord-010027-r0tl01kq	891	10	in	in	IN
cord-010027-r0tl01kq	891	11	two	two	CD
cord-010027-r0tl01kq	891	12	of	of	IN
cord-010027-r0tl01kq	891	13	the	the	DT
cord-010027-r0tl01kq	891	14	cases	case	NNS
cord-010027-r0tl01kq	891	15	analysed	analyse	VBN
cord-010027-r0tl01kq	891	16	as	as	IN
cord-010027-r0tl01kq	891	17	cell	cell	NN
cord-010027-r0tl01kq	891	18	blocks	block	NNS
cord-010027-r0tl01kq	891	19	.	.	.
cord-010027-r0tl01kq	892	1	The	the	DT
cord-010027-r0tl01kq	892	2	most	most	RBS
cord-010027-r0tl01kq	892	3	common	common	JJ
cord-010027-r0tl01kq	892	4	mutation	mutation	NN
cord-010027-r0tl01kq	892	5	,	,	,
cord-010027-r0tl01kq	892	6	a	a	DT
cord-010027-r0tl01kq	892	7	missense	missense	JJ
cord-010027-r0tl01kq	892	8	mutation	mutation	NN
cord-010027-r0tl01kq	892	9	at	at	IN
cord-010027-r0tl01kq	892	10	codon	codon	NNP
cord-010027-r0tl01kq	892	11	858	858	CD
cord-010027-r0tl01kq	892	12	of	of	IN
cord-010027-r0tl01kq	892	13	exon	exon	NNP
cord-010027-r0tl01kq	892	14	21	21	CD
cord-010027-r0tl01kq	892	15	,	,	,
cord-010027-r0tl01kq	892	16	was	be	VBD
cord-010027-r0tl01kq	892	17	most	most	RBS
cord-010027-r0tl01kq	892	18	frequently	frequently	RB
cord-010027-r0tl01kq	892	19	associated	associate	VBN
cord-010027-r0tl01kq	892	20	with	with	IN
cord-010027-r0tl01kq	892	21	an	an	DT
cord-010027-r0tl01kq	892	22	acinar	acinar	JJ
cord-010027-r0tl01kq	892	23	growth	growth	NN
cord-010027-r0tl01kq	892	24	pattern	pattern	NN
cord-010027-r0tl01kq	892	25	.	.	.
cord-010027-r0tl01kq	893	1	Of	of	IN
cord-010027-r0tl01kq	893	2	the	the	DT
cord-010027-r0tl01kq	893	3	2013	2013	CD
cord-010027-r0tl01kq	893	4	cases	case	NNS
cord-010027-r0tl01kq	893	5	,	,	,
cord-010027-r0tl01kq	893	6	22	22	CD
cord-010027-r0tl01kq	893	7	(	(	-LRB-
cord-010027-r0tl01kq	893	8	19	19	CD
cord-010027-r0tl01kq	893	9	%	%	NN
cord-010027-r0tl01kq	893	10	)	)	-RRB-
cord-010027-r0tl01kq	893	11	were	be	VBD
cord-010027-r0tl01kq	893	12	sent	send	VBN
cord-010027-r0tl01kq	893	13	for	for	IN
cord-010027-r0tl01kq	893	14	ALK	ALK	NNP
cord-010027-r0tl01kq	893	15	mutation	mutation	NN
cord-010027-r0tl01kq	893	16	analysis	analysis	NN
cord-010027-r0tl01kq	893	17	,	,	,
cord-010027-r0tl01kq	893	18	compared	compare	VBN
cord-010027-r0tl01kq	893	19	with	with	IN
cord-010027-r0tl01kq	893	20	152	152	CD
cord-010027-r0tl01kq	893	21	(	(	-LRB-
cord-010027-r0tl01kq	893	22	80	80	CD
cord-010027-r0tl01kq	893	23	%	%	NN
cord-010027-r0tl01kq	893	24	)	)	-RRB-
cord-010027-r0tl01kq	893	25	in	in	IN
cord-010027-r0tl01kq	893	26	2014	2014	CD
cord-010027-r0tl01kq	893	27	.	.	.
cord-010027-r0tl01kq	894	1	Both	both	DT
cord-010027-r0tl01kq	894	2	of	of	IN
cord-010027-r0tl01kq	894	3	the	the	DT
cord-010027-r0tl01kq	894	4	two	two	CD
cord-010027-r0tl01kq	894	5	cases	case	NNS
cord-010027-r0tl01kq	894	6	with	with	IN
cord-010027-r0tl01kq	894	7	an	an	DT
cord-010027-r0tl01kq	894	8	ALK	ALK	NNP
cord-010027-r0tl01kq	894	9	translocation	translocation	NN
cord-010027-r0tl01kq	894	10	(	(	-LRB-
cord-010027-r0tl01kq	894	11	2p23	2p23	CD
cord-010027-r0tl01kq	894	12	rearrangement	rearrangement	NN
cord-010027-r0tl01kq	894	13	)	)	-RRB-
cord-010027-r0tl01kq	894	14	showed	show	VBD
cord-010027-r0tl01kq	894	15	an	an	DT
cord-010027-r0tl01kq	894	16	acinar	acinar	JJ
cord-010027-r0tl01kq	894	17	growth	growth	NN
cord-010027-r0tl01kq	894	18	pattern	pattern	NN
cord-010027-r0tl01kq	894	19	.	.	.
cord-010027-r0tl01kq	895	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	895	2	compliance	compliance	NN
cord-010027-r0tl01kq	895	3	with	with	IN
cord-010027-r0tl01kq	895	4	College	College	NNP
cord-010027-r0tl01kq	895	5	guidelines	guideline	NNS
cord-010027-r0tl01kq	895	6	in	in	IN
cord-010027-r0tl01kq	895	7	sending	send	VBG
cord-010027-r0tl01kq	895	8	appropriate	appropriate	JJ
cord-010027-r0tl01kq	895	9	lung	lung	NN
cord-010027-r0tl01kq	895	10	specimens	specimen	NNS
cord-010027-r0tl01kq	895	11	for	for	IN
cord-010027-r0tl01kq	895	12	mutation	mutation	NN
cord-010027-r0tl01kq	895	13	analysis	analysis	NN
cord-010027-r0tl01kq	895	14	is	be	VBZ
cord-010027-r0tl01kq	895	15	improving	improve	VBG
cord-010027-r0tl01kq	895	16	.	.	.
cord-010027-r0tl01kq	896	1	The	the	DT
cord-010027-r0tl01kq	896	2	correlations	correlation	NNS
cord-010027-r0tl01kq	896	3	between	between	IN
cord-010027-r0tl01kq	896	4	mutation	mutation	NN
cord-010027-r0tl01kq	896	5	status	status	NN
cord-010027-r0tl01kq	896	6	and	and	CC
cord-010027-r0tl01kq	896	7	morphological	morphological	JJ
cord-010027-r0tl01kq	896	8	subtype	subtype	NN
cord-010027-r0tl01kq	896	9	add	add	VBP
cord-010027-r0tl01kq	896	10	to	to	IN
cord-010027-r0tl01kq	896	11	,	,	,
cord-010027-r0tl01kq	896	12	and	and	CC
cord-010027-r0tl01kq	896	13	are	be	VBP
cord-010027-r0tl01kq	896	14	in	in	IN
cord-010027-r0tl01kq	896	15	keeping	keep	VBG
cord-010027-r0tl01kq	896	16	with	with	IN
cord-010027-r0tl01kq	896	17	,	,	,
cord-010027-r0tl01kq	896	18	the	the	DT
cord-010027-r0tl01kq	896	19	current	current	JJ
cord-010027-r0tl01kq	896	20	body	body	NN
cord-010027-r0tl01kq	896	21	of	of	IN
cord-010027-r0tl01kq	896	22	evidence	evidence	NN
cord-010027-r0tl01kq	896	23	in	in	IN
cord-010027-r0tl01kq	896	24	this	this	DT
cord-010027-r0tl01kq	896	25	area	area	NN
cord-010027-r0tl01kq	896	26	.	.	.
cord-010027-r0tl01kq	897	1	Primary	primary	JJ
cord-010027-r0tl01kq	897	2	Synovial	Synovial	NNP
cord-010027-r0tl01kq	897	3	Sarcoma	Sarcoma	NNP
cord-010027-r0tl01kq	897	4	of	of	IN
cord-010027-r0tl01kq	897	5	the	the	DT
cord-010027-r0tl01kq	897	6	Heart	heart	NN
cord-010027-r0tl01kq	897	7	-An	-an	XX
cord-010027-r0tl01kq	898	1	Interesting	Interesting	NNP
cord-010027-r0tl01kq	898	2	Case	Case	NNP
cord-010027-r0tl01kq	898	3	Report	Report	NNP
cord-010027-r0tl01kq	898	4	and	and	CC
cord-010027-r0tl01kq	898	5	Review	Review	NNP
cord-010027-r0tl01kq	898	6	of	of	IN
cord-010027-r0tl01kq	898	7	Literature	Literature	NNP
cord-010027-r0tl01kq	898	8	P	P	NNP
cord-010027-r0tl01kq	898	9	S	S	NNP
cord-010027-r0tl01kq	898	10	Venkatesan	Venkatesan	NNP
cord-010027-r0tl01kq	898	11	1	1	CD
cord-010027-r0tl01kq	898	12	;	;	:
cord-010027-r0tl01kq	898	13	P	P	NNP
cord-010027-r0tl01kq	898	14	Sloan	Sloan	NNP
cord-010027-r0tl01kq	898	15	1	1	CD
cord-010027-r0tl01kq	898	16	;	;	:
cord-010027-r0tl01kq	898	17	S	S	NNP
cord-010027-r0tl01kq	898	18	Kendall	Kendall	NNP
cord-010027-r0tl01kq	898	19	2	2	CD
cord-010027-r0tl01kq	898	20	;	;	:
cord-010027-r0tl01kq	898	21	M	M	NNP
cord-010027-r0tl01kq	898	22	Giles	Giles	NNP
cord-010027-r0tl01kq	898	23	2	2	CD
cord-010027-r0tl01kq	898	24	1	1	CD
cord-010027-r0tl01kq	898	25	Royal	Royal	NNP
cord-010027-r0tl01kq	898	26	Victoria	Victoria	NNP
cord-010027-r0tl01kq	898	27	Infirmary	Infirmary	NNP
cord-010027-r0tl01kq	898	28	,	,	,
cord-010027-r0tl01kq	898	29	Newcastle	Newcastle	NNP
cord-010027-r0tl01kq	898	30	,	,	,
cord-010027-r0tl01kq	898	31	UK	UK	NNP
cord-010027-r0tl01kq	898	32	;	;	:
cord-010027-r0tl01kq	898	33	2	2	CD
cord-010027-r0tl01kq	898	34	James	James	NNP
cord-010027-r0tl01kq	898	35	Cook	Cook	NNP
cord-010027-r0tl01kq	898	36	University	University	NNP
cord-010027-r0tl01kq	898	37	Hospital	Hospital	NNP
cord-010027-r0tl01kq	898	38	,	,	,
cord-010027-r0tl01kq	898	39	Middlesbrough	Middlesbrough	NNP
cord-010027-r0tl01kq	898	40	,	,	,
cord-010027-r0tl01kq	899	1	UK	UK	NNP
cord-010027-r0tl01kq	899	2	Seventy	seventy	CD
cord-010027-r0tl01kq	899	3	five	five	CD
cord-010027-r0tl01kq	899	4	percent	percent	NN
cord-010027-r0tl01kq	899	5	of	of	IN
cord-010027-r0tl01kq	899	6	primary	primary	JJ
cord-010027-r0tl01kq	899	7	cardiac	cardiac	JJ
cord-010027-r0tl01kq	899	8	tumours	tumour	NNS
cord-010027-r0tl01kq	899	9	are	be	VBP
cord-010027-r0tl01kq	899	10	reported	report	VBN
cord-010027-r0tl01kq	899	11	to	to	TO
cord-010027-r0tl01kq	899	12	be	be	VB
cord-010027-r0tl01kq	899	13	benign	benign	JJ
cord-010027-r0tl01kq	899	14	atrial	atrial	JJ
cord-010027-r0tl01kq	899	15	myxomas	myxomas	NN
cord-010027-r0tl01kq	899	16	.	.	.
cord-010027-r0tl01kq	900	1	The	the	DT
cord-010027-r0tl01kq	900	2	remaining	remain	VBG
cord-010027-r0tl01kq	900	3	are	be	VBP
cord-010027-r0tl01kq	900	4	malignant	malignant	JJ
cord-010027-r0tl01kq	900	5	tumours	tumour	NNS
cord-010027-r0tl01kq	900	6	with	with	IN
cord-010027-r0tl01kq	900	7	most	most	JJS
cord-010027-r0tl01kq	900	8	of	of	IN
cord-010027-r0tl01kq	900	9	them	-PRON-	PRP
cord-010027-r0tl01kq	900	10	being	be	VBG
cord-010027-r0tl01kq	900	11	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	900	12	,	,	,
cord-010027-r0tl01kq	900	13	particularly	particularly	RB
cord-010027-r0tl01kq	900	14	angiosarcoma	angiosarcoma	NNP
cord-010027-r0tl01kq	900	15	and	and	CC
cord-010027-r0tl01kq	900	16	malignant	malignant	JJ
cord-010027-r0tl01kq	900	17	fibrous	fibrous	JJ
cord-010027-r0tl01kq	900	18	histiocytoma	histiocytoma	NN
cord-010027-r0tl01kq	900	19	.	.	.
cord-010027-r0tl01kq	901	1	Synovial	synovial	JJ
cord-010027-r0tl01kq	901	2	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	901	3	of	of	IN
cord-010027-r0tl01kq	901	4	the	the	DT
cord-010027-r0tl01kq	901	5	heart	heart	NN
cord-010027-r0tl01kq	901	6	is	be	VBZ
cord-010027-r0tl01kq	901	7	a	a	DT
cord-010027-r0tl01kq	901	8	very	very	RB
cord-010027-r0tl01kq	901	9	rare	rare	JJ
cord-010027-r0tl01kq	901	10	malignancy	malignancy	NN
cord-010027-r0tl01kq	901	11	accounting	account	VBG
cord-010027-r0tl01kq	901	12	for	for	IN
cord-010027-r0tl01kq	901	13	less	less	JJR
cord-010027-r0tl01kq	901	14	than	than	IN
cord-010027-r0tl01kq	901	15	1	1	CD
cord-010027-r0tl01kq	901	16	%	%	NN
cord-010027-r0tl01kq	901	17	of	of	IN
cord-010027-r0tl01kq	901	18	all	all	DT
cord-010027-r0tl01kq	901	19	primary	primary	JJ
cord-010027-r0tl01kq	901	20	cardiac	cardiac	JJ
cord-010027-r0tl01kq	901	21	tumours	tumour	NNS
cord-010027-r0tl01kq	901	22	.	.	.
cord-010027-r0tl01kq	902	1	Most	Most	JJS
cord-010027-r0tl01kq	902	2	of	of	IN
cord-010027-r0tl01kq	902	3	them	-PRON-	PRP
cord-010027-r0tl01kq	902	4	arise	arise	VBP
cord-010027-r0tl01kq	902	5	from	from	IN
cord-010027-r0tl01kq	902	6	the	the	DT
cord-010027-r0tl01kq	902	7	pericardium	pericardium	NN
cord-010027-r0tl01kq	902	8	and	and	CC
cord-010027-r0tl01kq	902	9	the	the	DT
cord-010027-r0tl01kq	902	10	right	right	JJ
cord-010027-r0tl01kq	902	11	side	side	NN
cord-010027-r0tl01kq	902	12	of	of	IN
cord-010027-r0tl01kq	902	13	the	the	DT
cord-010027-r0tl01kq	902	14	heart	heart	NN
cord-010027-r0tl01kq	902	15	and	and	CC
cord-010027-r0tl01kq	902	16	is	be	VBZ
cord-010027-r0tl01kq	902	17	considered	consider	VBN
cord-010027-r0tl01kq	902	18	to	to	TO
cord-010027-r0tl01kq	902	19	be	be	VB
cord-010027-r0tl01kq	902	20	highly	highly	RB
cord-010027-r0tl01kq	902	21	aggressive	aggressive	JJ
cord-010027-r0tl01kq	902	22	with	with	IN
cord-010027-r0tl01kq	902	23	reduced	reduce	VBN
cord-010027-r0tl01kq	902	24	survival	survival	NN
cord-010027-r0tl01kq	902	25	rates	rate	NNS
cord-010027-r0tl01kq	902	26	.	.	.
cord-010027-r0tl01kq	903	1	Diagnosis	diagnosis	NN
cord-010027-r0tl01kq	903	2	in	in	IN
cord-010027-r0tl01kq	903	3	these	these	DT
cord-010027-r0tl01kq	903	4	rare	rare	JJ
cord-010027-r0tl01kq	903	5	locations	location	NNS
cord-010027-r0tl01kq	903	6	is	be	VBZ
cord-010027-r0tl01kq	903	7	also	also	RB
cord-010027-r0tl01kq	903	8	challenging	challenging	JJ
cord-010027-r0tl01kq	903	9	.	.	.
cord-010027-r0tl01kq	904	1	We	-PRON-	PRP
cord-010027-r0tl01kq	904	2	report	report	VBP
cord-010027-r0tl01kq	904	3	a	a	DT
cord-010027-r0tl01kq	904	4	42-year	42-year	JJ
cord-010027-r0tl01kq	904	5	-	-	HYPH
cord-010027-r0tl01kq	904	6	old	old	JJ
cord-010027-r0tl01kq	904	7	gentleman	gentleman	NN
cord-010027-r0tl01kq	904	8	who	who	WP
cord-010027-r0tl01kq	904	9	presented	present	VBD
cord-010027-r0tl01kq	904	10	to	to	IN
cord-010027-r0tl01kq	904	11	us	-PRON-	PRP
cord-010027-r0tl01kq	904	12	with	with	IN
cord-010027-r0tl01kq	904	13	productive	productive	JJ
cord-010027-r0tl01kq	904	14	cough	cough	NN
cord-010027-r0tl01kq	904	15	,	,	,
cord-010027-r0tl01kq	904	16	chest	chest	NN
cord-010027-r0tl01kq	904	17	pain	pain	NN
cord-010027-r0tl01kq	904	18	and	and	CC
cord-010027-r0tl01kq	904	19	paroxysmal	paroxysmal	JJ
cord-010027-r0tl01kq	904	20	nocturnal	nocturnal	JJ
cord-010027-r0tl01kq	904	21	dyspnea	dyspnea	NN
cord-010027-r0tl01kq	904	22	.	.	.
cord-010027-r0tl01kq	905	1	Echocardiography	echocardiography	NN
cord-010027-r0tl01kq	905	2	revealed	reveal	VBD
cord-010027-r0tl01kq	905	3	a	a	DT
cord-010027-r0tl01kq	905	4	calcified	calcified	JJ
cord-010027-r0tl01kq	905	5	left	left	JJ
cord-010027-r0tl01kq	905	6	atrial	atrial	JJ
cord-010027-r0tl01kq	905	7	mass	mass	NN
cord-010027-r0tl01kq	905	8	arising	arise	VBG
cord-010027-r0tl01kq	905	9	from	from	IN
cord-010027-r0tl01kq	905	10	the	the	DT
cord-010027-r0tl01kq	905	11	posterior	posterior	JJ
cord-010027-r0tl01kq	905	12	leaflet	leaflet	NN
cord-010027-r0tl01kq	905	13	of	of	IN
cord-010027-r0tl01kq	905	14	the	the	DT
cord-010027-r0tl01kq	905	15	mitral	mitral	JJ
cord-010027-r0tl01kq	905	16	valve	valve	NN
cord-010027-r0tl01kq	905	17	and	and	CC
cord-010027-r0tl01kq	905	18	radiologically	radiologically	RB
cord-010027-r0tl01kq	905	19	was	be	VBD
cord-010027-r0tl01kq	905	20	thought	think	VBN
cord-010027-r0tl01kq	905	21	to	to	TO
cord-010027-r0tl01kq	905	22	be	be	VB
cord-010027-r0tl01kq	905	23	a	a	DT
cord-010027-r0tl01kq	905	24	benign	benign	JJ
cord-010027-r0tl01kq	905	25	atrial	atrial	JJ
cord-010027-r0tl01kq	905	26	myxoma	myxoma	NN
cord-010027-r0tl01kq	905	27	.	.	.
cord-010027-r0tl01kq	906	1	Excision	excision	NN
cord-010027-r0tl01kq	906	2	was	be	VBD
cord-010027-r0tl01kq	906	3	planned	plan	VBN
cord-010027-r0tl01kq	906	4	with	with	IN
cord-010027-r0tl01kq	906	5	histology	histology	NN
cord-010027-r0tl01kq	906	6	showing	show	VBG
cord-010027-r0tl01kq	906	7	a	a	DT
cord-010027-r0tl01kq	906	8	malignant	malignant	JJ
cord-010027-r0tl01kq	906	9	biphasic	biphasic	JJ
cord-010027-r0tl01kq	906	10	spindle	spindle	NN
cord-010027-r0tl01kq	906	11	cell	cell	NN
cord-010027-r0tl01kq	906	12	tumour	tumour	NN
cord-010027-r0tl01kq	906	13	exhibiting	exhibit	VBG
cord-010027-r0tl01kq	906	14	marked	mark	VBN
cord-010027-r0tl01kq	906	15	cellular	cellular	JJ
cord-010027-r0tl01kq	906	16	atypia	atypia	NN
cord-010027-r0tl01kq	906	17	and	and	CC
cord-010027-r0tl01kq	906	18	numerous	numerous	JJ
cord-010027-r0tl01kq	906	19	mitoses	mitose	NNS
cord-010027-r0tl01kq	906	20	.	.	.
cord-010027-r0tl01kq	907	1	On	on	IN
cord-010027-r0tl01kq	907	2	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	907	3	,	,	,
cord-010027-r0tl01kq	907	4	the	the	DT
cord-010027-r0tl01kq	907	5	glandular	glandular	JJ
cord-010027-r0tl01kq	907	6	component	component	NN
cord-010027-r0tl01kq	907	7	expressed	express	VBD
cord-010027-r0tl01kq	907	8	diffuse	diffuse	JJ
cord-010027-r0tl01kq	907	9	positive	positive	JJ
cord-010027-r0tl01kq	907	10	staining	staining	NN
cord-010027-r0tl01kq	907	11	for	for	IN
cord-010027-r0tl01kq	907	12	Bcl-2	Bcl-2	NNP
cord-010027-r0tl01kq	907	13	and	and	CC
cord-010027-r0tl01kq	907	14	EMA	EMA	NNP
cord-010027-r0tl01kq	907	15	with	with	IN
cord-010027-r0tl01kq	907	16	focal	focal	JJ
cord-010027-r0tl01kq	907	17	positive	positive	JJ
cord-010027-r0tl01kq	907	18	staining	staining	NN
cord-010027-r0tl01kq	907	19	for	for	IN
cord-010027-r0tl01kq	907	20	pancytokeratins	pancytokeratin	NNS
cord-010027-r0tl01kq	907	21	.	.	.
cord-010027-r0tl01kq	908	1	The	the	DT
cord-010027-r0tl01kq	908	2	spindle	spindle	NN
cord-010027-r0tl01kq	908	3	cell	cell	NN
cord-010027-r0tl01kq	908	4	component	component	NN
cord-010027-r0tl01kq	908	5	expressed	express	VBD
cord-010027-r0tl01kq	908	6	CD99	CD99	NNP
cord-010027-r0tl01kq	908	7	and	and	CC
cord-010027-r0tl01kq	908	8	EMA	EMA	NNP
cord-010027-r0tl01kq	908	9	and	and	CC
cord-010027-r0tl01kq	908	10	was	be	VBD
cord-010027-r0tl01kq	908	11	found	find	VBN
cord-010027-r0tl01kq	908	12	to	to	TO
cord-010027-r0tl01kq	908	13	be	be	VB
cord-010027-r0tl01kq	908	14	negative	negative	JJ
cord-010027-r0tl01kq	908	15	for	for	IN
cord-010027-r0tl01kq	908	16	CD34	CD34	NNP
cord-010027-r0tl01kq	908	17	,	,	,
cord-010027-r0tl01kq	908	18	S100	S100	NNP
cord-010027-r0tl01kq	908	19	,	,	,
cord-010027-r0tl01kq	908	20	desmin	desmin	NNP
cord-010027-r0tl01kq	908	21	,	,	,
cord-010027-r0tl01kq	908	22	Melan	Melan	NNP
cord-010027-r0tl01kq	908	23	-	-	HYPH
cord-010027-r0tl01kq	908	24	A	A	NNP
cord-010027-r0tl01kq	908	25	and	and	CC
cord-010027-r0tl01kq	908	26	HMB-45	HMB-45	NNP
cord-010027-r0tl01kq	908	27	.	.	.
cord-010027-r0tl01kq	909	1	Cytogenetic	cytogenetic	JJ
cord-010027-r0tl01kq	909	2	testing	testing	NN
cord-010027-r0tl01kq	909	3	revealed	reveal	VBD
cord-010027-r0tl01kq	909	4	SS18-SSX1/2	SS18-SSX1/2	NNP
cord-010027-r0tl01kq	909	5	gene	gene	NN
cord-010027-r0tl01kq	909	6	fusion	fusion	NN
cord-010027-r0tl01kq	909	7	with	with	IN
cord-010027-r0tl01kq	909	8	SS18	SS18	NNP
cord-010027-r0tl01kq	909	9	rearrangement	rearrangement	NN
cord-010027-r0tl01kq	909	10	confirming	confirm	VBG
cord-010027-r0tl01kq	909	11	the	the	DT
cord-010027-r0tl01kq	909	12	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	909	13	of	of	IN
cord-010027-r0tl01kq	909	14	synovial	synovial	JJ
cord-010027-r0tl01kq	909	15	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	909	16	in	in	IN
cord-010027-r0tl01kq	909	17	this	this	DT
cord-010027-r0tl01kq	909	18	rare	rare	JJ
cord-010027-r0tl01kq	909	19	location	location	NN
cord-010027-r0tl01kq	909	20	.	.	.
cord-010027-r0tl01kq	910	1	A	a	DT
cord-010027-r0tl01kq	910	2	postoperative	postoperative	JJ
cord-010027-r0tl01kq	910	3	computed	compute	VBN
cord-010027-r0tl01kq	910	4	tomography	tomography	NN
cord-010027-r0tl01kq	910	5	was	be	VBD
cord-010027-r0tl01kq	910	6	performed	perform	VBN
cord-010027-r0tl01kq	910	7	which	which	WDT
cord-010027-r0tl01kq	910	8	showed	show	VBD
cord-010027-r0tl01kq	910	9	no	no	DT
cord-010027-r0tl01kq	910	10	evidence	evidence	NN
cord-010027-r0tl01kq	910	11	of	of	IN
cord-010027-r0tl01kq	910	12	metastasis	metastasis	NN
cord-010027-r0tl01kq	910	13	or	or	CC
cord-010027-r0tl01kq	910	14	primary	primary	JJ
cord-010027-r0tl01kq	910	15	lesions	lesion	NNS
cord-010027-r0tl01kq	910	16	elsewhere	elsewhere	RB
cord-010027-r0tl01kq	910	17	.	.	.
cord-010027-r0tl01kq	911	1	There	there	EX
cord-010027-r0tl01kq	911	2	was	be	VBD
cord-010027-r0tl01kq	911	3	excellent	excellent	JJ
cord-010027-r0tl01kq	911	4	postoperative	postoperative	JJ
cord-010027-r0tl01kq	911	5	surgical	surgical	JJ
cord-010027-r0tl01kq	911	6	recovery	recovery	NN
cord-010027-r0tl01kq	911	7	and	and	CC
cord-010027-r0tl01kq	911	8	adjuvant	adjuvant	JJ
cord-010027-r0tl01kq	912	1	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	912	2	was	be	VBD
cord-010027-r0tl01kq	912	3	considered	consider	VBN
cord-010027-r0tl01kq	912	4	in	in	IN
cord-010027-r0tl01kq	912	5	the	the	DT
cord-010027-r0tl01kq	912	6	multi	multi	JJ
cord-010027-r0tl01kq	912	7	disciplinary	disciplinary	JJ
cord-010027-r0tl01kq	912	8	meeting	meeting	NN
cord-010027-r0tl01kq	912	9	.	.	.
cord-010027-r0tl01kq	913	1	Primary	primary	JJ
cord-010027-r0tl01kq	913	2	cardiac	cardiac	JJ
cord-010027-r0tl01kq	913	3	synovial	synovial	JJ
cord-010027-r0tl01kq	913	4	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	913	5	is	be	VBZ
cord-010027-r0tl01kq	913	6	an	an	DT
cord-010027-r0tl01kq	913	7	extremely	extremely	RB
cord-010027-r0tl01kq	913	8	rare	rare	JJ
cord-010027-r0tl01kq	913	9	malignancy	malignancy	NN
cord-010027-r0tl01kq	913	10	especially	especially	RB
cord-010027-r0tl01kq	913	11	when	when	WRB
cord-010027-r0tl01kq	913	12	arising	arise	VBG
cord-010027-r0tl01kq	913	13	from	from	IN
cord-010027-r0tl01kq	913	14	the	the	DT
cord-010027-r0tl01kq	913	15	left	left	JJ
cord-010027-r0tl01kq	913	16	atrium	atrium	NN
cord-010027-r0tl01kq	913	17	posing	pose	VBG
cord-010027-r0tl01kq	913	18	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	913	19	difficulty	difficulty	NN
cord-010027-r0tl01kq	913	20	mimicking	mimic	VBG
cord-010027-r0tl01kq	913	21	atrial	atrial	JJ
cord-010027-r0tl01kq	913	22	myxoma	myxoma	NN
cord-010027-r0tl01kq	913	23	.	.	.
cord-010027-r0tl01kq	914	1	In	in	IN
cord-010027-r0tl01kq	914	2	contrast	contrast	NN
cord-010027-r0tl01kq	914	3	to	to	IN
cord-010027-r0tl01kq	914	4	the	the	DT
cord-010027-r0tl01kq	914	5	poor	poor	JJ
cord-010027-r0tl01kq	914	6	prognosis	prognosis	NN
cord-010027-r0tl01kq	914	7	mentioned	mention	VBN
cord-010027-r0tl01kq	914	8	in	in	IN
cord-010027-r0tl01kq	914	9	the	the	DT
cord-010027-r0tl01kq	914	10	literatures	literature	NNS
cord-010027-r0tl01kq	914	11	,	,	,
cord-010027-r0tl01kq	914	12	there	there	EX
cord-010027-r0tl01kq	914	13	was	be	VBD
cord-010027-r0tl01kq	914	14	excellent	excellent	JJ
cord-010027-r0tl01kq	914	15	recovery	recovery	NN
cord-010027-r0tl01kq	914	16	in	in	IN
cord-010027-r0tl01kq	914	17	this	this	DT
cord-010027-r0tl01kq	914	18	gentleman	gentleman	NN
cord-010027-r0tl01kq	914	19	.	.	.
cord-010027-r0tl01kq	915	1	Swyer	Swyer	NNP
cord-010027-r0tl01kq	915	2	-	-	HYPH
cord-010027-r0tl01kq	915	3	James	James	NNP
cord-010027-r0tl01kq	915	4	-	-	HYPH
cord-010027-r0tl01kq	915	5	MacLeod	MacLeod	NNP
cord-010027-r0tl01kq	915	6	syndrome	syndrome	NN
cord-010027-r0tl01kq	915	7	(	(	-LRB-
cord-010027-r0tl01kq	915	8	SJMLS	SJMLS	NNP
cord-010027-r0tl01kq	915	9	)	)	-RRB-
cord-010027-r0tl01kq	915	10	is	be	VBZ
cord-010027-r0tl01kq	915	11	a	a	DT
cord-010027-r0tl01kq	915	12	rare	rare	JJ
cord-010027-r0tl01kq	915	13	lung	lung	NN
cord-010027-r0tl01kq	915	14	condition	condition	NN
cord-010027-r0tl01kq	915	15	that	that	WDT
cord-010027-r0tl01kq	915	16	manifests	manifest	VBZ
cord-010027-r0tl01kq	915	17	radiologically	radiologically	RB
cord-010027-r0tl01kq	915	18	as	as	IN
cord-010027-r0tl01kq	915	19	unilateral	unilateral	JJ
cord-010027-r0tl01kq	915	20	hemithorax	hemithorax	NN
cord-010027-r0tl01kq	915	21	lucency	lucency	NNP
cord-010027-r0tl01kq	915	22	as	as	IN
cord-010027-r0tl01kq	915	23	a	a	DT
cord-010027-r0tl01kq	915	24	result	result	NN
cord-010027-r0tl01kq	915	25	of	of	IN
cord-010027-r0tl01kq	915	26	post	post	JJ
cord-010027-r0tl01kq	915	27	-	-	JJ
cord-010027-r0tl01kq	915	28	infectious	infectious	JJ
cord-010027-r0tl01kq	915	29	obliterative	obliterative	JJ
cord-010027-r0tl01kq	915	30	bronchiolitis	bronchiolitis	NN
cord-010027-r0tl01kq	915	31	,	,	,
cord-010027-r0tl01kq	915	32	leading	lead	VBG
cord-010027-r0tl01kq	915	33	to	to	IN
cord-010027-r0tl01kq	915	34	small	small	JJ
cord-010027-r0tl01kq	915	35	airways	airway	NNS
cord-010027-r0tl01kq	915	36	obstruction	obstruction	NN
cord-010027-r0tl01kq	915	37	and	and	CC
cord-010027-r0tl01kq	915	38	secondary	secondary	JJ
cord-010027-r0tl01kq	915	39	emphysema	emphysema	NN
cord-010027-r0tl01kq	915	40	.	.	.
cord-010027-r0tl01kq	916	1	The	the	DT
cord-010027-r0tl01kq	916	2	histological	histological	JJ
cord-010027-r0tl01kq	916	3	features	feature	NNS
cord-010027-r0tl01kq	916	4	of	of	IN
cord-010027-r0tl01kq	916	5	SJMLS	SJMLS	NNP
cord-010027-r0tl01kq	916	6	are	be	VBP
cord-010027-r0tl01kq	916	7	poorly	poorly	RB
cord-010027-r0tl01kq	916	8	and	and	CC
cord-010027-r0tl01kq	916	9	infrequently	infrequently	RB
cord-010027-r0tl01kq	916	10	described	describe	VBN
cord-010027-r0tl01kq	916	11	.	.	.
cord-010027-r0tl01kq	917	1	We	-PRON-	PRP
cord-010027-r0tl01kq	917	2	present	present	VBP
cord-010027-r0tl01kq	917	3	three	three	CD
cord-010027-r0tl01kq	917	4	cases	case	NNS
cord-010027-r0tl01kq	917	5	of	of	IN
cord-010027-r0tl01kq	917	6	the	the	DT
cord-010027-r0tl01kq	917	7	syndrome	syndrome	NN
cord-010027-r0tl01kq	917	8	that	that	WDT
cord-010027-r0tl01kq	917	9	underwent	undergo	VBD
cord-010027-r0tl01kq	917	10	lobectomies	lobectomy	NNS
cord-010027-r0tl01kq	917	11	in	in	IN
cord-010027-r0tl01kq	917	12	our	-PRON-	PRP$
cord-010027-r0tl01kq	917	13	institution	institution	NN
cord-010027-r0tl01kq	917	14	from	from	IN
cord-010027-r0tl01kq	917	15	2013	2013	CD
cord-010027-r0tl01kq	917	16	to	to	IN
cord-010027-r0tl01kq	917	17	2015	2015	CD
cord-010027-r0tl01kq	917	18	,	,	,
cord-010027-r0tl01kq	917	19	in	in	IN
cord-010027-r0tl01kq	917	20	three	three	CD
cord-010027-r0tl01kq	917	21	women	woman	NNS
cord-010027-r0tl01kq	917	22	,	,	,
cord-010027-r0tl01kq	917	23	aged	aged	JJ
cord-010027-r0tl01kq	917	24	,	,	,
cord-010027-r0tl01kq	917	25	33	33	CD
cord-010027-r0tl01kq	917	26	,	,	,
cord-010027-r0tl01kq	917	27	46	46	CD
cord-010027-r0tl01kq	917	28	and	and	CC
cord-010027-r0tl01kq	917	29	22	22	CD
cord-010027-r0tl01kq	917	30	years	year	NNS
cord-010027-r0tl01kq	917	31	,	,	,
cord-010027-r0tl01kq	917	32	presenting	present	VBG
cord-010027-r0tl01kq	917	33	with	with	IN
cord-010027-r0tl01kq	917	34	recurrent	recurrent	JJ
cord-010027-r0tl01kq	917	35	lower	low	JJR
cord-010027-r0tl01kq	917	36	respiratory	respiratory	JJ
cord-010027-r0tl01kq	917	37	tract	tract	NN
cord-010027-r0tl01kq	917	38	infection	infection	NN
cord-010027-r0tl01kq	917	39	,	,	,
cord-010027-r0tl01kq	917	40	shortness	shortness	NN
cord-010027-r0tl01kq	917	41	of	of	IN
cord-010027-r0tl01kq	917	42	breath	breath	NN
cord-010027-r0tl01kq	917	43	and	and	CC
cord-010027-r0tl01kq	917	44	pleuritic	pleuritic	JJ
cord-010027-r0tl01kq	917	45	chest	chest	NN
cord-010027-r0tl01kq	917	46	pain	pain	NN
cord-010027-r0tl01kq	917	47	.	.	.
cord-010027-r0tl01kq	918	1	Two	two	CD
cord-010027-r0tl01kq	918	2	underwent	undergo	VBD
cord-010027-r0tl01kq	918	3	left	left	JJ
cord-010027-r0tl01kq	918	4	upper	upper	JJ
cord-010027-r0tl01kq	918	5	lobectomies	lobectomy	NNS
cord-010027-r0tl01kq	918	6	,	,	,
cord-010027-r0tl01kq	918	7	one	one	CD
cord-010027-r0tl01kq	918	8	left	leave	VBD
cord-010027-r0tl01kq	918	9	lower	low	JJR
cord-010027-r0tl01kq	918	10	lobectomy	lobectomy	NN
cord-010027-r0tl01kq	918	11	.	.	.
cord-010027-r0tl01kq	919	1	The	the	DT
cord-010027-r0tl01kq	919	2	first	first	JJ
cord-010027-r0tl01kq	919	3	case	case	NN
cord-010027-r0tl01kq	919	4	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	919	5	hyperlucency	hyperlucency	NN
cord-010027-r0tl01kq	919	6	of	of	IN
cord-010027-r0tl01kq	919	7	the	the	DT
cord-010027-r0tl01kq	919	8	affected	affect	VBN
cord-010027-r0tl01kq	919	9	lobe	lobe	NN
cord-010027-r0tl01kq	919	10	with	with	IN
cord-010027-r0tl01kq	919	11	markedly	markedly	RB
cord-010027-r0tl01kq	919	12	reduced	reduce	VBN
cord-010027-r0tl01kq	919	13	blood	blood	NN
cord-010027-r0tl01kq	919	14	vessel	vessel	NN
cord-010027-r0tl01kq	919	15	attenuation	attenuation	NN
cord-010027-r0tl01kq	919	16	.	.	.
cord-010027-r0tl01kq	920	1	The	the	DT
cord-010027-r0tl01kq	920	2	radiological	radiological	JJ
cord-010027-r0tl01kq	920	3	findings	finding	NNS
cord-010027-r0tl01kq	920	4	of	of	IN
cord-010027-r0tl01kq	920	5	the	the	DT
cord-010027-r0tl01kq	920	6	second	second	JJ
cord-010027-r0tl01kq	920	7	case	case	NN
cord-010027-r0tl01kq	920	8	were	be	VBD
cord-010027-r0tl01kq	920	9	of	of	IN
cord-010027-r0tl01kq	920	10	extensive	extensive	JJ
cord-010027-r0tl01kq	920	11	bronchiectasis	bronchiectasis	NN
cord-010027-r0tl01kq	920	12	,	,	,
cord-010027-r0tl01kq	920	13	hyperlucency	hyperlucency	NN
cord-010027-r0tl01kq	920	14	,	,	,
cord-010027-r0tl01kq	920	15	mucus	mucus	NN
cord-010027-r0tl01kq	920	16	plugging	plugging	NN
cord-010027-r0tl01kq	920	17	and	and	CC
cord-010027-r0tl01kq	920	18	hypervascularity	hypervascularity	NN
cord-010027-r0tl01kq	920	19	.	.	.
cord-010027-r0tl01kq	921	1	The	the	DT
cord-010027-r0tl01kq	921	2	radiological	radiological	JJ
cord-010027-r0tl01kq	921	3	findings	finding	NNS
cord-010027-r0tl01kq	921	4	of	of	IN
cord-010027-r0tl01kq	921	5	the	the	DT
cord-010027-r0tl01kq	921	6	third	third	JJ
cord-010027-r0tl01kq	921	7	case	case	NN
cord-010027-r0tl01kq	921	8	were	be	VBD
cord-010027-r0tl01kq	921	9	of	of	IN
cord-010027-r0tl01kq	921	10	an	an	DT
cord-010027-r0tl01kq	921	11	apical	apical	JJ
cord-010027-r0tl01kq	921	12	bulla	bulla	NN
cord-010027-r0tl01kq	921	13	and	and	CC
cord-010027-r0tl01kq	921	14	upper	upper	JJ
cord-010027-r0tl01kq	921	15	lobe	lobe	NN
cord-010027-r0tl01kq	921	16	cavitating	cavitate	VBG
cord-010027-r0tl01kq	921	17	lesion	lesion	NN
cord-010027-r0tl01kq	921	18	with	with	IN
cord-010027-r0tl01kq	921	19	lobar	lobar	NNP
cord-010027-r0tl01kq	921	20	hypolucency	hypolucency	NNP
cord-010027-r0tl01kq	921	21	and	and	CC
cord-010027-r0tl01kq	921	22	hypoperfusion	hypoperfusion	NN
cord-010027-r0tl01kq	921	23	.	.	.
cord-010027-r0tl01kq	922	1	The	the	DT
cord-010027-r0tl01kq	922	2	main	main	JJ
cord-010027-r0tl01kq	922	3	histological	histological	JJ
cord-010027-r0tl01kq	922	4	findings	finding	NNS
cord-010027-r0tl01kq	922	5	were	be	VBD
cord-010027-r0tl01kq	922	6	bronchiolar	bronchiolar	JJ
cord-010027-r0tl01kq	922	7	changes	change	NNS
cord-010027-r0tl01kq	922	8	with	with	IN
cord-010027-r0tl01kq	922	9	bronchiolectasis	bronchiolectasis	NNP
cord-010027-r0tl01kq	922	10	,	,	,
cord-010027-r0tl01kq	922	11	mucus	mucus	NN
cord-010027-r0tl01kq	922	12	plugging	plugging	NN
cord-010027-r0tl01kq	922	13	,	,	,
cord-010027-r0tl01kq	922	14	constrictive	constrictive	JJ
cord-010027-r0tl01kq	922	15	/	/	SYM
cord-010027-r0tl01kq	922	16	obliterative	obliterative	JJ
cord-010027-r0tl01kq	922	17	bronchiolitis	bronchiolitis	NN
cord-010027-r0tl01kq	922	18	and	and	CC
cord-010027-r0tl01kq	922	19	various	various	JJ
cord-010027-r0tl01kq	922	20	degree	degree	NN
cord-010027-r0tl01kq	922	21	of	of	IN
cord-010027-r0tl01kq	922	22	peribronchiolar	peribronchiolar	JJ
cord-010027-r0tl01kq	922	23	inflammation	inflammation	NN
cord-010027-r0tl01kq	922	24	.	.	.
cord-010027-r0tl01kq	923	1	Emphysema	emphysema	NN
cord-010027-r0tl01kq	923	2	was	be	VBD
cord-010027-r0tl01kq	923	3	mild	mild	JJ
cord-010027-r0tl01kq	923	4	and	and	CC
cord-010027-r0tl01kq	923	5	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	923	6	as	as	IN
cord-010027-r0tl01kq	923	7	loss	loss	NN
cord-010027-r0tl01kq	923	8	of	of	IN
cord-010027-r0tl01kq	923	9	attachment	attachment	NN
cord-010027-r0tl01kq	923	10	of	of	IN
cord-010027-r0tl01kq	923	11	alveolar	alveolar	JJ
cord-010027-r0tl01kq	923	12	walls	wall	NNS
cord-010027-r0tl01kq	923	13	.	.	.
cord-010027-r0tl01kq	924	1	In	in	IN
cord-010027-r0tl01kq	924	2	addition	addition	NN
cord-010027-r0tl01kq	924	3	,	,	,
cord-010027-r0tl01kq	924	4	Case	case	NN
cord-010027-r0tl01kq	924	5	1	1	CD
cord-010027-r0tl01kq	924	6	had	have	VBD
cord-010027-r0tl01kq	924	7	dystrophic	dystrophic	JJ
cord-010027-r0tl01kq	924	8	,	,	,
cord-010027-r0tl01kq	924	9	hypoplastic	hypoplastic	JJ
cord-010027-r0tl01kq	924	10	or	or	CC
cord-010027-r0tl01kq	924	11	absent	absent	JJ
cord-010027-r0tl01kq	924	12	branches	branch	NNS
cord-010027-r0tl01kq	924	13	of	of	IN
cord-010027-r0tl01kq	924	14	the	the	DT
cord-010027-r0tl01kq	924	15	pulmonary	pulmonary	JJ
cord-010027-r0tl01kq	924	16	arteries	artery	NNS
cord-010027-r0tl01kq	924	17	.	.	.
cord-010027-r0tl01kq	925	1	Case	case	NN
cord-010027-r0tl01kq	925	2	2	2	CD
cord-010027-r0tl01kq	925	3	showed	show	VBD
cord-010027-r0tl01kq	925	4	prominent	prominent	JJ
cord-010027-r0tl01kq	925	5	bronchial	bronchial	JJ
cord-010027-r0tl01kq	925	6	arterioles	arteriole	NNS
cord-010027-r0tl01kq	925	7	and	and	CC
cord-010027-r0tl01kq	925	8	abnormal	abnormal	JJ
cord-010027-r0tl01kq	925	9	tortuous	tortuous	JJ
cord-010027-r0tl01kq	925	10	dilated	dilated	JJ
cord-010027-r0tl01kq	925	11	pulmonary	pulmonary	JJ
cord-010027-r0tl01kq	925	12	arteries	artery	NNS
cord-010027-r0tl01kq	925	13	and	and	CC
cord-010027-r0tl01kq	925	14	veins	vein	NNS
cord-010027-r0tl01kq	925	15	.	.	.
cord-010027-r0tl01kq	926	1	Case	case	NN
cord-010027-r0tl01kq	926	2	3	3	CD
cord-010027-r0tl01kq	926	3	had	have	VBD
cord-010027-r0tl01kq	926	4	established	establish	VBN
cord-010027-r0tl01kq	926	5	bronchiolar	bronchiolar	JJ
cord-010027-r0tl01kq	926	6	scars	scar	NNS
cord-010027-r0tl01kq	926	7	in	in	IN
cord-010027-r0tl01kq	926	8	the	the	DT
cord-010027-r0tl01kq	926	9	bronchovascular	bronchovascular	JJ
cord-010027-r0tl01kq	926	10	bundles	bundle	NNS
cord-010027-r0tl01kq	926	11	,	,	,
cord-010027-r0tl01kq	926	12	pleural	pleural	JJ
cord-010027-r0tl01kq	926	13	arteries	artery	NNS
cord-010027-r0tl01kq	926	14	showed	show	VBD
cord-010027-r0tl01kq	926	15	medial	medial	JJ
cord-010027-r0tl01kq	926	16	hypertrophy	hypertrophy	NN
cord-010027-r0tl01kq	926	17	and	and	CC
cord-010027-r0tl01kq	926	18	the	the	DT
cord-010027-r0tl01kq	926	19	interlobular	interlobular	NNP
cord-010027-r0tl01kq	926	20	septa	septa	NNP
cord-010027-r0tl01kq	926	21	contained	contain	VBD
cord-010027-r0tl01kq	926	22	dilated	dilated	JJ
cord-010027-r0tl01kq	926	23	prominent	prominent	JJ
cord-010027-r0tl01kq	926	24	veins	vein	NNS
cord-010027-r0tl01kq	926	25	,	,	,
cord-010027-r0tl01kq	926	26	as	as	RB
cord-010027-r0tl01kq	926	27	well	well	RB
cord-010027-r0tl01kq	926	28	as	as	IN
cord-010027-r0tl01kq	926	29	cystically	cystically	RB
cord-010027-r0tl01kq	926	30	dilated	dilate	VBD
cord-010027-r0tl01kq	926	31	inflamed	inflamed	JJ
cord-010027-r0tl01kq	926	32	peripheral	peripheral	JJ
cord-010027-r0tl01kq	926	33	bronchus	bronchus	NN
cord-010027-r0tl01kq	926	34	.	.	.
cord-010027-r0tl01kq	927	1	These	these	DT
cord-010027-r0tl01kq	927	2	cases	case	NNS
cord-010027-r0tl01kq	927	3	highlight	highlight	VBP
cord-010027-r0tl01kq	927	4	the	the	DT
cord-010027-r0tl01kq	927	5	importance	importance	NN
cord-010027-r0tl01kq	927	6	of	of	IN
cord-010027-r0tl01kq	927	7	vascular	vascular	JJ
cord-010027-r0tl01kq	927	8	changes	change	NNS
cord-010027-r0tl01kq	927	9	in	in	IN
cord-010027-r0tl01kq	927	10	SJMLS	SJMLS	NNP
cord-010027-r0tl01kq	927	11	,	,	,
cord-010027-r0tl01kq	927	12	likely	likely	RB
cord-010027-r0tl01kq	927	13	secondary	secondary	JJ
cord-010027-r0tl01kq	927	14	to	to	IN
cord-010027-r0tl01kq	927	15	the	the	DT
cord-010027-r0tl01kq	927	16	bronchiolar	bronchiolar	JJ
cord-010027-r0tl01kq	927	17	inflammation	inflammation	NN
cord-010027-r0tl01kq	927	18	and	and	CC
cord-010027-r0tl01kq	927	19	destruction	destruction	NN
cord-010027-r0tl01kq	927	20	leading	lead	VBG
cord-010027-r0tl01kq	927	21	to	to	IN
cord-010027-r0tl01kq	927	22	capillary	capillary	JJ
cord-010027-r0tl01kq	927	23	bed	bed	NN
cord-010027-r0tl01kq	927	24	destruction	destruction	NN
cord-010027-r0tl01kq	927	25	from	from	IN
cord-010027-r0tl01kq	927	26	secondary	secondary	JJ
cord-010027-r0tl01kq	927	27	emphysema	emphysema	NN
cord-010027-r0tl01kq	927	28	and	and	CC
cord-010027-r0tl01kq	927	29	reactive	reactive	JJ
cord-010027-r0tl01kq	927	30	pulmonary	pulmonary	JJ
cord-010027-r0tl01kq	927	31	and	and	CC
cord-010027-r0tl01kq	927	32	arterial	arterial	JJ
cord-010027-r0tl01kq	927	33	changes	change	NNS
cord-010027-r0tl01kq	927	34	.	.	.
cord-010027-r0tl01kq	928	1	Mediastinal	Mediastinal	NNP
cord-010027-r0tl01kq	928	2	nodal	nodal	JJ
cord-010027-r0tl01kq	928	3	staging	staging	NN
cord-010027-r0tl01kq	928	4	with	with	IN
cord-010027-r0tl01kq	928	5	EBUS	EBUS	NNP
cord-010027-r0tl01kq	928	6	is	be	VBZ
cord-010027-r0tl01kq	928	7	recommended	recommend	VBN
cord-010027-r0tl01kq	928	8	for	for	IN
cord-010027-r0tl01kq	928	9	patients	patient	NNS
cord-010027-r0tl01kq	928	10	with	with	IN
cord-010027-r0tl01kq	928	11	resectable	resectable	JJ
cord-010027-r0tl01kq	928	12	non	non	JJ
cord-010027-r0tl01kq	928	13	-	-	JJ
cord-010027-r0tl01kq	928	14	small	small	JJ
cord-010027-r0tl01kq	928	15	cell	cell	NN
cord-010027-r0tl01kq	928	16	lung	lung	NN
cord-010027-r0tl01kq	928	17	cancer	cancer	NN
cord-010027-r0tl01kq	928	18	and	and	CC
cord-010027-r0tl01kq	928	19	has	have	VBZ
cord-010027-r0tl01kq	928	20	emerged	emerge	VBN
cord-010027-r0tl01kq	928	21	as	as	IN
cord-010027-r0tl01kq	928	22	a	a	DT
cord-010027-r0tl01kq	928	23	safe	safe	JJ
cord-010027-r0tl01kq	928	24	tool	tool	NN
cord-010027-r0tl01kq	928	25	to	to	TO
cord-010027-r0tl01kq	928	26	establish	establish	VB
cord-010027-r0tl01kq	928	27	granulomatous	granulomatous	JJ
cord-010027-r0tl01kq	928	28	pathology	pathology	NN
cord-010027-r0tl01kq	928	29	in	in	IN
cord-010027-r0tl01kq	928	30	suspected	suspect	VBN
cord-010027-r0tl01kq	928	31	sarcoidosis	sarcoidosis	NN
cord-010027-r0tl01kq	928	32	.	.	.
cord-010027-r0tl01kq	929	1	We	-PRON-	PRP
cord-010027-r0tl01kq	929	2	conducted	conduct	VBD
cord-010027-r0tl01kq	929	3	a	a	DT
cord-010027-r0tl01kq	929	4	retrospective	retrospective	JJ
cord-010027-r0tl01kq	929	5	analysis	analysis	NN
cord-010027-r0tl01kq	929	6	of	of	IN
cord-010027-r0tl01kq	929	7	the	the	DT
cord-010027-r0tl01kq	929	8	outcomes	outcome	NNS
cord-010027-r0tl01kq	929	9	of	of	IN
cord-010027-r0tl01kq	929	10	EBUS	EBUS	NNP
cord-010027-r0tl01kq	929	11	performed	perform	VBD
cord-010027-r0tl01kq	929	12	in	in	IN
cord-010027-r0tl01kq	929	13	a	a	DT
cord-010027-r0tl01kq	929	14	large	large	JJ
cord-010027-r0tl01kq	929	15	teaching	teaching	NN
cord-010027-r0tl01kq	929	16	university	university	NN
cord-010027-r0tl01kq	929	17	hospital	hospital	NN
cord-010027-r0tl01kq	929	18	with	with	IN
cord-010027-r0tl01kq	929	19	a	a	DT
cord-010027-r0tl01kq	929	20	rapid	rapid	JJ
cord-010027-r0tl01kq	929	21	access	access	NN
cord-010027-r0tl01kq	929	22	lung	lung	NN
cord-010027-r0tl01kq	929	23	clinic	clinic	NN
cord-010027-r0tl01kq	929	24	over	over	IN
cord-010027-r0tl01kq	929	25	a	a	DT
cord-010027-r0tl01kq	929	26	12	12	CD
cord-010027-r0tl01kq	929	27	month	month	NN
cord-010027-r0tl01kq	929	28	period	period	NN
cord-010027-r0tl01kq	929	29	and	and	CC
cord-010027-r0tl01kq	929	30	correlation	correlation	NN
cord-010027-r0tl01kq	929	31	with	with	IN
cord-010027-r0tl01kq	929	32	endobronchial	endobronchial	NNP
cord-010027-r0tl01kq	929	33	and	and	CC
cord-010027-r0tl01kq	929	34	CT	CT	NNP
cord-010027-r0tl01kq	929	35	guided	guide	VBN
cord-010027-r0tl01kq	929	36	biopsies	biopsy	NNS
cord-010027-r0tl01kq	929	37	,	,	,
cord-010027-r0tl01kq	929	38	and	and	CC
cord-010027-r0tl01kq	929	39	surgical	surgical	JJ
cord-010027-r0tl01kq	929	40	resections	resection	NNS
cord-010027-r0tl01kq	929	41	,	,	,
cord-010027-r0tl01kq	929	42	when	when	WRB
cord-010027-r0tl01kq	929	43	available	available	JJ
cord-010027-r0tl01kq	929	44	,	,	,
cord-010027-r0tl01kq	929	45	and	and	CC
cord-010027-r0tl01kq	929	46	compared	compare	VBD
cord-010027-r0tl01kq	929	47	the	the	DT
cord-010027-r0tl01kq	929	48	adequacy	adequacy	NN
cord-010027-r0tl01kq	929	49	of	of	IN
cord-010027-r0tl01kq	929	50	EBUS	EBUS	NNP
cord-010027-r0tl01kq	929	51	when	when	WRB
cord-010027-r0tl01kq	929	52	performed	perform	VBN
cord-010027-r0tl01kq	929	53	with	with	IN
cord-010027-r0tl01kq	929	54	and	and	CC
cord-010027-r0tl01kq	929	55	without	without	IN
cord-010027-r0tl01kq	929	56	rapid	rapid	JJ
cord-010027-r0tl01kq	929	57	on	on	IN
cord-010027-r0tl01kq	929	58	-	-	HYPH
cord-010027-r0tl01kq	929	59	site	site	NN
cord-010027-r0tl01kq	929	60	evaluation	evaluation	NN
cord-010027-r0tl01kq	929	61	(	(	-LRB-
cord-010027-r0tl01kq	929	62	ROSE	ROSE	NNP
cord-010027-r0tl01kq	929	63	Background	Background	NNP
cord-010027-r0tl01kq	929	64	and	and	CC
cord-010027-r0tl01kq	929	65	aims	aim	VBZ
cord-010027-r0tl01kq	929	66	:	:	:
cord-010027-r0tl01kq	929	67	In	in	IN
cord-010027-r0tl01kq	929	68	Interstitial	interstitial	JJ
cord-010027-r0tl01kq	929	69	lung	lung	NN
cord-010027-r0tl01kq	929	70	disease	disease	NN
cord-010027-r0tl01kq	929	71	(	(	-LRB-
cord-010027-r0tl01kq	929	72	ILD	ILD	NNP
cord-010027-r0tl01kq	929	73	)	)	-RRB-
cord-010027-r0tl01kq	929	74	,	,	,
cord-010027-r0tl01kq	929	75	when	when	WRB
cord-010027-r0tl01kq	929	76	an	an	DT
cord-010027-r0tl01kq	929	77	aetiological	aetiological	JJ
cord-010027-r0tl01kq	929	78	factor	factor	NN
cord-010027-r0tl01kq	929	79	appears	appear	VBZ
cord-010027-r0tl01kq	929	80	absent	absent	JJ
cord-010027-r0tl01kq	929	81	and	and	CC
cord-010027-r0tl01kq	929	82	clinical	clinical	JJ
cord-010027-r0tl01kq	929	83	-	-	HYPH
cord-010027-r0tl01kq	929	84	radiological	radiological	JJ
cord-010027-r0tl01kq	929	85	correlation	correlation	NN
cord-010027-r0tl01kq	929	86	is	be	VBZ
cord-010027-r0tl01kq	929	87	non	non	JJ
cord-010027-r0tl01kq	929	88	-	-	JJ
cord-010027-r0tl01kq	929	89	contributory	contributory	JJ
cord-010027-r0tl01kq	929	90	,	,	,
cord-010027-r0tl01kq	929	91	histology	histology	NN
cord-010027-r0tl01kq	929	92	is	be	VBZ
cord-010027-r0tl01kq	929	93	required	require	VBN
cord-010027-r0tl01kq	929	94	.	.	.
cord-010027-r0tl01kq	930	1	The	the	DT
cord-010027-r0tl01kq	930	2	traditional	traditional	JJ
cord-010027-r0tl01kq	930	3	surgical	surgical	JJ
cord-010027-r0tl01kq	930	4	lung	lung	NN
cord-010027-r0tl01kq	930	5	biopsy	biopsy	NN
cord-010027-r0tl01kq	930	6	(	(	-LRB-
cord-010027-r0tl01kq	930	7	SLB	SLB	NNP
cord-010027-r0tl01kq	930	8	)	)	-RRB-
cord-010027-r0tl01kq	930	9	is	be	VBZ
cord-010027-r0tl01kq	930	10	not	not	RB
cord-010027-r0tl01kq	930	11	without	without	IN
cord-010027-r0tl01kq	930	12	risks	risk	NNS
cord-010027-r0tl01kq	930	13	.	.	.
cord-010027-r0tl01kq	931	1	Cryotechnically	Cryotechnically	NNP
cord-010027-r0tl01kq	931	2	obtained	obtain	VBD
cord-010027-r0tl01kq	931	3	specimens	specimen	NNS
cord-010027-r0tl01kq	931	4	contain	contain	VBP
cord-010027-r0tl01kq	931	5	more	more	RBR
cord-010027-r0tl01kq	931	6	alveolated	alveolated	JJ
cord-010027-r0tl01kq	931	7	lung	lung	NN
cord-010027-r0tl01kq	931	8	tissue	tissue	NN
cord-010027-r0tl01kq	931	9	and	and	CC
cord-010027-r0tl01kq	931	10	less	less	JJR
cord-010027-r0tl01kq	931	11	crush	crush	NN
cord-010027-r0tl01kq	931	12	artefact	artefact	NN
cord-010027-r0tl01kq	931	13	than	than	IN
cord-010027-r0tl01kq	931	14	conventional	conventional	JJ
cord-010027-r0tl01kq	931	15	transbronchial	transbronchial	JJ
cord-010027-r0tl01kq	931	16	biopsies	biopsy	NNS
cord-010027-r0tl01kq	931	17	and	and	CC
cord-010027-r0tl01kq	931	18	may	may	MD
cord-010027-r0tl01kq	931	19	offer	offer	VB
cord-010027-r0tl01kq	931	20	an	an	DT
cord-010027-r0tl01kq	931	21	alternative	alternative	NN
cord-010027-r0tl01kq	931	22	to	to	IN
cord-010027-r0tl01kq	931	23	SLB	SLB	NNP
cord-010027-r0tl01kq	931	24	in	in	IN
cord-010027-r0tl01kq	931	25	selected	select	VBN
cord-010027-r0tl01kq	931	26	cases	case	NNS
cord-010027-r0tl01kq	931	27	.	.	.
cord-010027-r0tl01kq	932	1	We	-PRON-	PRP
cord-010027-r0tl01kq	932	2	aimed	aim	VBD
cord-010027-r0tl01kq	932	3	at	at	IN
cord-010027-r0tl01kq	932	4	studying	study	VBG
cord-010027-r0tl01kq	932	5	the	the	DT
cord-010027-r0tl01kq	932	6	complications	complication	NNS
cord-010027-r0tl01kq	932	7	of	of	IN
cord-010027-r0tl01kq	932	8	cryoprobe	cryoprobe	NN
cord-010027-r0tl01kq	932	9	transbronchial	transbronchial	JJ
cord-010027-r0tl01kq	932	10	lung	lung	NNP
cord-010027-r0tl01kq	932	11	biopsy	biopsy	NNP
cord-010027-r0tl01kq	932	12	(	(	-LRB-
cord-010027-r0tl01kq	932	13	CPBx	CPBx	NNP
cord-010027-r0tl01kq	932	14	)	)	-RRB-
cord-010027-r0tl01kq	932	15	and	and	CC
cord-010027-r0tl01kq	932	16	the	the	DT
cord-010027-r0tl01kq	932	17	quality	quality	NN
cord-010027-r0tl01kq	932	18	and	and	CC
cord-010027-r0tl01kq	932	19	pathological	pathological	JJ
cord-010027-r0tl01kq	932	20	characteristics	characteristic	NNS
cord-010027-r0tl01kq	932	21	of	of	IN
cord-010027-r0tl01kq	932	22	the	the	DT
cord-010027-r0tl01kq	932	23	tissue	tissue	NN
cord-010027-r0tl01kq	932	24	obtained	obtain	VBN
cord-010027-r0tl01kq	932	25	.	.	.
cord-010027-r0tl01kq	933	1	Methods	method	NNS
cord-010027-r0tl01kq	933	2	:	:	:
cord-010027-r0tl01kq	933	3	This	this	DT
cord-010027-r0tl01kq	933	4	is	be	VBZ
cord-010027-r0tl01kq	933	5	a	a	DT
cord-010027-r0tl01kq	933	6	prospective	prospective	JJ
cord-010027-r0tl01kq	933	7	study	study	NN
cord-010027-r0tl01kq	933	8	of	of	IN
cord-010027-r0tl01kq	933	9	patients	patient	NNS
cord-010027-r0tl01kq	933	10	who	who	WP
cord-010027-r0tl01kq	933	11	were	be	VBD
cord-010027-r0tl01kq	933	12	selected	select	VBN
cord-010027-r0tl01kq	933	13	for	for	IN
cord-010027-r0tl01kq	933	14	CPBx	CPBx	NNS
cord-010027-r0tl01kq	933	15	including	include	VBG
cord-010027-r0tl01kq	933	16	cases	case	NNS
cord-010027-r0tl01kq	933	17	of	of	IN
cord-010027-r0tl01kq	933	18	possible	possible	JJ
cord-010027-r0tl01kq	933	19	/	/	SYM
cord-010027-r0tl01kq	933	20	probable	probable	JJ
cord-010027-r0tl01kq	933	21	idiopathic	idiopathic	JJ
cord-010027-r0tl01kq	933	22	pulmonary	pulmonary	JJ
cord-010027-r0tl01kq	933	23	fibrosis	fibrosis	NN
cord-010027-r0tl01kq	933	24	(	(	-LRB-
cord-010027-r0tl01kq	933	25	IPF	IPF	NNP
cord-010027-r0tl01kq	933	26	)	)	-RRB-
cord-010027-r0tl01kq	933	27	.	.	.
cord-010027-r0tl01kq	934	1	Complications	complication	NNS
cord-010027-r0tl01kq	934	2	of	of	IN
cord-010027-r0tl01kq	934	3	the	the	DT
cord-010027-r0tl01kq	934	4	procedure	procedure	NN
cord-010027-r0tl01kq	934	5	as	as	RB
cord-010027-r0tl01kq	934	6	well	well	RB
cord-010027-r0tl01kq	934	7	as	as	IN
cord-010027-r0tl01kq	934	8	the	the	DT
cord-010027-r0tl01kq	934	9	quality	quality	NN
cord-010027-r0tl01kq	934	10	and	and	CC
cord-010027-r0tl01kq	934	11	pathological	pathological	JJ
cord-010027-r0tl01kq	934	12	characteristics	characteristic	NNS
cord-010027-r0tl01kq	934	13	of	of	IN
cord-010027-r0tl01kq	934	14	the	the	DT
cord-010027-r0tl01kq	934	15	tissue	tissue	NN
cord-010027-r0tl01kq	934	16	are	be	VBP
cord-010027-r0tl01kq	934	17	studied	study	VBN
cord-010027-r0tl01kq	934	18	.	.	.
cord-010027-r0tl01kq	935	1	Results	result	NNS
cord-010027-r0tl01kq	935	2	:	:	:
cord-010027-r0tl01kq	936	1	Twenty	twenty	CD
cord-010027-r0tl01kq	936	2	-	-	HYPH
cord-010027-r0tl01kq	936	3	seven	seven	CD
cord-010027-r0tl01kq	936	4	procedures	procedure	NNS
cord-010027-r0tl01kq	936	5	were	be	VBD
cord-010027-r0tl01kq	936	6	performed	perform	VBN
cord-010027-r0tl01kq	936	7	in	in	IN
cord-010027-r0tl01kq	936	8	24	24	CD
cord-010027-r0tl01kq	936	9	patients	patient	NNS
cord-010027-r0tl01kq	936	10	,	,	,
cord-010027-r0tl01kq	936	11	20	20	CD
cord-010027-r0tl01kq	936	12	of	of	IN
cord-010027-r0tl01kq	936	13	which	which	WDT
cord-010027-r0tl01kq	936	14	were	be	VBD
cord-010027-r0tl01kq	936	15	radiologically	radiologically	RB
cord-010027-r0tl01kq	936	16	IPF	IPF	NNP
cord-010027-r0tl01kq	936	17	.	.	.
cord-010027-r0tl01kq	937	1	A	a	DT
cord-010027-r0tl01kq	937	2	total	total	NN
cord-010027-r0tl01kq	937	3	of	of	IN
cord-010027-r0tl01kq	937	4	77	77	CD
cord-010027-r0tl01kq	937	5	biopsies	biopsy	NNS
cord-010027-r0tl01kq	937	6	were	be	VBD
cord-010027-r0tl01kq	937	7	obtained	obtain	VBN
cord-010027-r0tl01kq	937	8	(	(	-LRB-
cord-010027-r0tl01kq	937	9	Average	average	JJ
cord-010027-r0tl01kq	937	10	2.85	2.85	CD
cord-010027-r0tl01kq	937	11	biopsies	biopsy	NNS
cord-010027-r0tl01kq	937	12	per	per	IN
cord-010027-r0tl01kq	937	13	procedure	procedure	NN
cord-010027-r0tl01kq	937	14	)	)	-RRB-
cord-010027-r0tl01kq	937	15	.	.	.
cord-010027-r0tl01kq	938	1	Only	only	RB
cord-010027-r0tl01kq	938	2	one	one	CD
cord-010027-r0tl01kq	938	3	was	be	VBD
cord-010027-r0tl01kq	938	4	inadequate	inadequate	JJ
cord-010027-r0tl01kq	938	5	initially	initially	RB
cord-010027-r0tl01kq	938	6	.	.	.
cord-010027-r0tl01kq	939	1	Fibroblast	Fibroblast	NNP
cord-010027-r0tl01kq	939	2	foci	foci	NN
cord-010027-r0tl01kq	939	3	and	and	CC
cord-010027-r0tl01kq	939	4	features	feature	VBZ
cord-010027-r0tl01kq	939	5	consistent	consistent	JJ
cord-010027-r0tl01kq	939	6	with	with	IN
cord-010027-r0tl01kq	940	1	usual	usual	JJ
cord-010027-r0tl01kq	940	2	interstitial	interstitial	JJ
cord-010027-r0tl01kq	940	3	pneumonia	pneumonia	NN
cord-010027-r0tl01kq	940	4	(	(	-LRB-
cord-010027-r0tl01kq	940	5	UIP	UIP	NNP
cord-010027-r0tl01kq	940	6	)	)	-RRB-
cord-010027-r0tl01kq	940	7	pattern	pattern	NN
cord-010027-r0tl01kq	940	8	were	be	VBD
cord-010027-r0tl01kq	940	9	present	present	JJ
cord-010027-r0tl01kq	940	10	in	in	IN
cord-010027-r0tl01kq	940	11	18	18	CD
cord-010027-r0tl01kq	940	12	biopsies	biopsy	NNS
cord-010027-r0tl01kq	940	13	from	from	IN
cord-010027-r0tl01kq	940	14	16	16	CD
cord-010027-r0tl01kq	940	15	patients	patient	NNS
cord-010027-r0tl01kq	940	16	(	(	-LRB-
cord-010027-r0tl01kq	940	17	66.7	66.7	CD
cord-010027-r0tl01kq	940	18	%	%	NN
cord-010027-r0tl01kq	940	19	of	of	IN
cord-010027-r0tl01kq	940	20	total	total	NN
cord-010027-r0tl01kq	940	21	;	;	:
cord-010027-r0tl01kq	940	22	80	80	CD
cord-010027-r0tl01kq	940	23	%	%	NN
cord-010027-r0tl01kq	940	24	of	of	IN
cord-010027-r0tl01kq	940	25	suspected	suspect	VBN
cord-010027-r0tl01kq	940	26	IPF	IPF	NNP
cord-010027-r0tl01kq	940	27	cases	case	NNS
cord-010027-r0tl01kq	940	28	)	)	-RRB-
cord-010027-r0tl01kq	940	29	.	.	.
cord-010027-r0tl01kq	941	1	Granulomas	granuloma	NNS
cord-010027-r0tl01kq	941	2	were	be	VBD
cord-010027-r0tl01kq	941	3	identified	identify	VBN
cord-010027-r0tl01kq	941	4	in	in	IN
cord-010027-r0tl01kq	941	5	4	4	CD
cord-010027-r0tl01kq	941	6	patients	patient	NNS
cord-010027-r0tl01kq	941	7	(	(	-LRB-
cord-010027-r0tl01kq	941	8	16.7	16.7	CD
cord-010027-r0tl01kq	941	9	%	%	NN
cord-010027-r0tl01kq	941	10	)	)	-RRB-
cord-010027-r0tl01kq	941	11	,	,	,
cord-010027-r0tl01kq	941	12	3	3	CD
cord-010027-r0tl01kq	941	13	of	of	IN
cord-010027-r0tl01kq	941	14	which	which	WDT
cord-010027-r0tl01kq	941	15	were	be	VBD
cord-010027-r0tl01kq	941	16	radiologically	radiologically	RB
cord-010027-r0tl01kq	941	17	suspected	suspect	VBN
cord-010027-r0tl01kq	941	18	IPF	IPF	NNP
cord-010027-r0tl01kq	941	19	(	(	-LRB-
cord-010027-r0tl01kq	941	20	15	15	CD
cord-010027-r0tl01kq	941	21	%	%	NN
cord-010027-r0tl01kq	941	22	of	of	IN
cord-010027-r0tl01kq	941	23	suspected	suspect	VBN
cord-010027-r0tl01kq	941	24	IPF	IPF	NNP
cord-010027-r0tl01kq	941	25	cases	case	NNS
cord-010027-r0tl01kq	941	26	)	)	-RRB-
cord-010027-r0tl01kq	941	27	.	.	.
cord-010027-r0tl01kq	942	1	Two	two	CD
cord-010027-r0tl01kq	942	2	patients	patient	NNS
cord-010027-r0tl01kq	942	3	(	(	-LRB-
cord-010027-r0tl01kq	942	4	8.3	8.3	CD
cord-010027-r0tl01kq	942	5	%	%	NN
cord-010027-r0tl01kq	942	6	)	)	-RRB-
cord-010027-r0tl01kq	942	7	had	have	VBD
cord-010027-r0tl01kq	942	8	organizing	organize	VBG
cord-010027-r0tl01kq	942	9	pneumonia	pneumonia	NN
cord-010027-r0tl01kq	942	10	;	;	:
cord-010027-r0tl01kq	942	11	both	both	DT
cord-010027-r0tl01kq	942	12	were	be	VBD
cord-010027-r0tl01kq	942	13	inconsistent	inconsistent	JJ
cord-010027-r0tl01kq	942	14	with	with	IN
cord-010027-r0tl01kq	942	15	IPF	IPF	NNP
cord-010027-r0tl01kq	942	16	radiologically	radiologically	RB
cord-010027-r0tl01kq	942	17	.	.	.
cord-010027-r0tl01kq	943	1	The	the	DT
cord-010027-r0tl01kq	943	2	findings	finding	NNS
cord-010027-r0tl01kq	943	3	in	in	IN
cord-010027-r0tl01kq	943	4	the	the	DT
cord-010027-r0tl01kq	943	5	remaining	remain	VBG
cord-010027-r0tl01kq	943	6	3	3	CD
cord-010027-r0tl01kq	943	7	patients	patient	NNS
cord-010027-r0tl01kq	943	8	were	be	VBD
cord-010027-r0tl01kq	943	9	nonspecific	nonspecific	JJ
cord-010027-r0tl01kq	943	10	;	;	:
cord-010027-r0tl01kq	943	11	two	two	CD
cord-010027-r0tl01kq	943	12	of	of	IN
cord-010027-r0tl01kq	943	13	these	these	DT
cord-010027-r0tl01kq	943	14	were	be	VBD
cord-010027-r0tl01kq	943	15	radiologically	radiologically	RB
cord-010027-r0tl01kq	943	16	IPF	IPF	NNP
cord-010027-r0tl01kq	943	17	(	(	-LRB-
cord-010027-r0tl01kq	943	18	10	10	CD
cord-010027-r0tl01kq	943	19	%	%	NN
cord-010027-r0tl01kq	943	20	of	of	IN
cord-010027-r0tl01kq	943	21	IPF	IPF	NNP
cord-010027-r0tl01kq	943	22	cases	case	NNS
cord-010027-r0tl01kq	943	23	)	)	-RRB-
cord-010027-r0tl01kq	943	24	.	.	.
cord-010027-r0tl01kq	944	1	Seven	seven	CD
cord-010027-r0tl01kq	944	2	patients	patient	NNS
cord-010027-r0tl01kq	944	3	(	(	-LRB-
cord-010027-r0tl01kq	944	4	25.9	25.9	CD
cord-010027-r0tl01kq	944	5	%	%	NN
cord-010027-r0tl01kq	944	6	of	of	IN
cord-010027-r0tl01kq	944	7	procedures	procedure	NNS
cord-010027-r0tl01kq	944	8	)	)	-RRB-
cord-010027-r0tl01kq	944	9	developed	develop	VBD
cord-010027-r0tl01kq	944	10	pneumothorax	pneumothorax	NN
cord-010027-r0tl01kq	944	11	,	,	,
cord-010027-r0tl01kq	944	12	only	only	RB
cord-010027-r0tl01kq	944	13	2	2	CD
cord-010027-r0tl01kq	944	14	of	of	IN
cord-010027-r0tl01kq	944	15	them	-PRON-	PRP
cord-010027-r0tl01kq	944	16	(	(	-LRB-
cord-010027-r0tl01kq	944	17	7.4	7.4	CD
cord-010027-r0tl01kq	944	18	%	%	NN
cord-010027-r0tl01kq	944	19	)	)	-RRB-
cord-010027-r0tl01kq	944	20	required	require	VBN
cord-010027-r0tl01kq	944	21	chest	chest	NN
cord-010027-r0tl01kq	944	22	tube	tube	NN
cord-010027-r0tl01kq	944	23	drainage	drainage	NN
cord-010027-r0tl01kq	944	24	.	.	.
cord-010027-r0tl01kq	945	1	Five	five	CD
cord-010027-r0tl01kq	945	2	patients	patient	NNS
cord-010027-r0tl01kq	945	3	(	(	-LRB-
cord-010027-r0tl01kq	945	4	18.5	18.5	CD
cord-010027-r0tl01kq	945	5	%	%	NN
cord-010027-r0tl01kq	945	6	)	)	-RRB-
cord-010027-r0tl01kq	945	7	developed	developed	JJ
cord-010027-r0tl01kq	945	8	bleeding	bleeding	NN
cord-010027-r0tl01kq	945	9	(	(	-LRB-
cord-010027-r0tl01kq	945	10	moderate	moderate	JJ
cord-010027-r0tl01kq	945	11	in	in	IN
cord-010027-r0tl01kq	945	12	3	3	CD
cord-010027-r0tl01kq	945	13	(	(	-LRB-
cord-010027-r0tl01kq	945	14	11.1	11.1	CD
cord-010027-r0tl01kq	945	15	%	%	NN
cord-010027-r0tl01kq	945	16	)	)	-RRB-
cord-010027-r0tl01kq	945	17	and	and	CC
cord-010027-r0tl01kq	945	18	mild	mild	JJ
cord-010027-r0tl01kq	945	19	in	in	IN
cord-010027-r0tl01kq	945	20	2	2	CD
cord-010027-r0tl01kq	945	21	(	(	-LRB-
cord-010027-r0tl01kq	945	22	7.4	7.4	CD
cord-010027-r0tl01kq	945	23	%	%	NN
cord-010027-r0tl01kq	945	24	)	)	-RRB-
cord-010027-r0tl01kq	945	25	)	)	-RRB-
cord-010027-r0tl01kq	945	26	.	.	.
cord-010027-r0tl01kq	946	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	946	2	:	:	:
cord-010027-r0tl01kq	946	3	CPBx	CPBx	NNP
cord-010027-r0tl01kq	946	4	was	be	VBD
cord-010027-r0tl01kq	946	5	useful	useful	JJ
cord-010027-r0tl01kq	946	6	in	in	IN
cord-010027-r0tl01kq	946	7	this	this	DT
cord-010027-r0tl01kq	946	8	cohort	cohort	NN
cord-010027-r0tl01kq	946	9	at	at	IN
cord-010027-r0tl01kq	946	10	potentially	potentially	RB
cord-010027-r0tl01kq	946	11	identifying	identify	VBG
cord-010027-r0tl01kq	946	12	features	feature	NNS
cord-010027-r0tl01kq	946	13	not	not	RB
cord-010027-r0tl01kq	946	14	typical	typical	JJ
cord-010027-r0tl01kq	946	15	of	of	IN
cord-010027-r0tl01kq	946	16	IPF	IPF	NNP
cord-010027-r0tl01kq	946	17	and	and	CC
cord-010027-r0tl01kq	946	18	displayed	display	VBD
cord-010027-r0tl01kq	946	19	an	an	DT
cord-010027-r0tl01kq	946	20	acceptable	acceptable	JJ
cord-010027-r0tl01kq	946	21	complication	complication	NN
cord-010027-r0tl01kq	946	22	rate	rate	NN
cord-010027-r0tl01kq	946	23	.	.	.
cord-010027-r0tl01kq	947	1	Cardiomyopathy	Cardiomyopathy	NNP
cord-010027-r0tl01kq	947	2	ZJ	ZJ	NNP
cord-010027-r0tl01kq	947	3	van	van	NNP
cord-010027-r0tl01kq	947	4	der	der	NNP
cord-010027-r0tl01kq	947	5	Klooster	Klooster	NNP
cord-010027-r0tl01kq	947	6	1	1	CD
cord-010027-r0tl01kq	947	7	;	;	:
cord-010027-r0tl01kq	947	8	S	S	NNP
cord-010027-r0tl01kq	947	9	Sepehrkhouy	Sepehrkhouy	NNP
cord-010027-r0tl01kq	947	10	1	1	CD
cord-010027-r0tl01kq	947	11	;	;	:
cord-010027-r0tl01kq	947	12	M	M	NNP
cord-010027-r0tl01kq	947	13	Harakalova	Harakalova	NNP
cord-010027-r0tl01kq	947	14	1	1	CD
cord-010027-r0tl01kq	947	15	;	;	:
cord-010027-r0tl01kq	947	16	R	R	NNP
cord-010027-r0tl01kq	947	17	Goldschmeding	Goldschmeding	NNP
cord-010027-r0tl01kq	947	18	1	1	CD
cord-010027-r0tl01kq	947	19	;	;	:
cord-010027-r0tl01kq	948	1	N	N	NNP
cord-010027-r0tl01kq	948	2	de	de	NNP
cord-010027-r0tl01kq	948	3	Jonge	Jonge	NNP
cord-010027-r0tl01kq	948	4	1	1	CD
cord-010027-r0tl01kq	948	5	;	;	:
cord-010027-r0tl01kq	948	6	AJH	AJH	NNP
cord-010027-r0tl01kq	948	7	Suurmeijer	Suurmeijer	NNP
cord-010027-r0tl01kq	948	8	2	2	CD
cord-010027-r0tl01kq	948	9	;	;	:
cord-010027-r0tl01kq	948	10	RA	RA	NNP
cord-010027-r0tl01kq	948	11	de	de	NNP
cord-010027-r0tl01kq	948	12	Weger	Weger	NNP
cord-010027-r0tl01kq	948	13	1	1	CD
cord-010027-r0tl01kq	948	14	;	;	:
cord-010027-r0tl01kq	948	15	F	F	NNP
cord-010027-r0tl01kq	948	16	Asselbergs	Asselbergs	NNP
cord-010027-r0tl01kq	948	17	1	1	CD
cord-010027-r0tl01kq	948	18	;	;	:
cord-010027-r0tl01kq	949	1	P	p	NN
cord-010027-r0tl01kq	949	2	A	a	NN
cord-010027-r0tl01kq	950	1	Vink	Vink	NNP
cord-010027-r0tl01kq	950	2	1	1	CD
cord-010027-r0tl01kq	950	3	Introduction	introduction	NN
cord-010027-r0tl01kq	950	4	:	:	:
cord-010027-r0tl01kq	951	1	Genetic	genetic	JJ
cord-010027-r0tl01kq	951	2	dilated	dilated	JJ
cord-010027-r0tl01kq	951	3	cardiomyopathy	cardiomyopathy	NN
cord-010027-r0tl01kq	951	4	is	be	VBZ
cord-010027-r0tl01kq	951	5	a	a	DT
cord-010027-r0tl01kq	951	6	heterogenous	heterogenous	JJ
cord-010027-r0tl01kq	951	7	group	group	NN
cord-010027-r0tl01kq	951	8	of	of	IN
cord-010027-r0tl01kq	951	9	diseases	disease	NNS
cord-010027-r0tl01kq	951	10	caused	cause	VBN
cord-010027-r0tl01kq	951	11	by	by	IN
cord-010027-r0tl01kq	951	12	mutations	mutation	NNS
cord-010027-r0tl01kq	951	13	in	in	IN
cord-010027-r0tl01kq	951	14	various	various	JJ
cord-010027-r0tl01kq	951	15	genes	gene	NNS
cord-010027-r0tl01kq	951	16	.	.	.
cord-010027-r0tl01kq	952	1	Several	several	JJ
cord-010027-r0tl01kq	952	2	types	type	NNS
cord-010027-r0tl01kq	952	3	of	of	IN
cord-010027-r0tl01kq	952	4	cardiomyocyte	cardiomyocyte	NNP
cord-010027-r0tl01kq	952	5	cell	cell	NN
cord-010027-r0tl01kq	952	6	death	death	NN
cord-010027-r0tl01kq	952	7	have	have	VBP
cord-010027-r0tl01kq	952	8	been	be	VBN
cord-010027-r0tl01kq	952	9	implicated	implicate	VBN
cord-010027-r0tl01kq	952	10	in	in	IN
cord-010027-r0tl01kq	952	11	dilated	dilated	JJ
cord-010027-r0tl01kq	952	12	cardiomyopathy	cardiomyopathy	NN
cord-010027-r0tl01kq	952	13	:	:	:
cord-010027-r0tl01kq	952	14	(	(	-LRB-
cord-010027-r0tl01kq	952	15	macro)autophagy	macro)autophagy	NNP
cord-010027-r0tl01kq	952	16	-	-	HYPH
cord-010027-r0tl01kq	952	17	related	relate	VBN
cord-010027-r0tl01kq	952	18	cell	cell	NN
cord-010027-r0tl01kq	952	19	death	death	NN
cord-010027-r0tl01kq	952	20	,	,	,
cord-010027-r0tl01kq	952	21	apoptosis	apoptosis	NN
cord-010027-r0tl01kq	952	22	,	,	,
cord-010027-r0tl01kq	952	23	necroptosis	necroptosis	NNP
cord-010027-r0tl01kq	952	24	and	and	CC
cord-010027-r0tl01kq	952	25	oncosis	oncosis	NNP
cord-010027-r0tl01kq	952	26	.	.	.
cord-010027-r0tl01kq	953	1	One	one	CD
cord-010027-r0tl01kq	953	2	plausible	plausible	JJ
cord-010027-r0tl01kq	953	3	mechanism	mechanism	NN
cord-010027-r0tl01kq	953	4	of	of	IN
cord-010027-r0tl01kq	953	5	genetic	genetic	JJ
cord-010027-r0tl01kq	953	6	cardiomyopathy	cardiomyopathy	NN
cord-010027-r0tl01kq	953	7	is	be	VBZ
cord-010027-r0tl01kq	953	8	proteotoxicity	proteotoxicity	NN
cord-010027-r0tl01kq	953	9	of	of	IN
cord-010027-r0tl01kq	953	10	accumulated	accumulate	VBN
cord-010027-r0tl01kq	953	11	protein	protein	NN
cord-010027-r0tl01kq	953	12	aggregates	aggregate	NNS
cord-010027-r0tl01kq	953	13	.	.	.
cord-010027-r0tl01kq	954	1	We	-PRON-	PRP
cord-010027-r0tl01kq	954	2	investigated	investigate	VBD
cord-010027-r0tl01kq	954	3	the	the	DT
cord-010027-r0tl01kq	954	4	association	association	NN
cord-010027-r0tl01kq	954	5	of	of	IN
cord-010027-r0tl01kq	954	6	such	such	JJ
cord-010027-r0tl01kq	954	7	aggregates	aggregate	NNS
cord-010027-r0tl01kq	954	8	as	as	IN
cord-010027-r0tl01kq	954	9	sign	sign	NN
cord-010027-r0tl01kq	954	10	of	of	IN
cord-010027-r0tl01kq	954	11	autophagy	autophagy	NN
cord-010027-r0tl01kq	954	12	-	-	HYPH
cord-010027-r0tl01kq	954	13	related	relate	VBN
cord-010027-r0tl01kq	954	14	cardiomyocyte	cardiomyocyte	NNP
cord-010027-r0tl01kq	954	15	cell	cell	NN
cord-010027-r0tl01kq	954	16	death	death	NN
cord-010027-r0tl01kq	954	17	with	with	IN
cord-010027-r0tl01kq	954	18	specific	specific	JJ
cord-010027-r0tl01kq	954	19	pathogenic	pathogenic	JJ
cord-010027-r0tl01kq	954	20	mutations	mutation	NNS
cord-010027-r0tl01kq	954	21	.	.	.
cord-010027-r0tl01kq	955	1	Methods	method	NNS
cord-010027-r0tl01kq	955	2	:	:	:
cord-010027-r0tl01kq	955	3	Hearts	heart	NNS
cord-010027-r0tl01kq	955	4	from	from	IN
cord-010027-r0tl01kq	955	5	30	30	CD
cord-010027-r0tl01kq	955	6	patients	patient	NNS
cord-010027-r0tl01kq	955	7	with	with	IN
cord-010027-r0tl01kq	955	8	a	a	DT
cord-010027-r0tl01kq	955	9	genetic	genetic	JJ
cord-010027-r0tl01kq	955	10	dilated	dilated	JJ
cord-010027-r0tl01kq	955	11	cardiomyopathy	cardiomyopathy	NN
cord-010027-r0tl01kq	955	12	or	or	CC
cord-010027-r0tl01kq	955	13	a	a	DT
cord-010027-r0tl01kq	955	14	combined	combined	JJ
cord-010027-r0tl01kq	955	15	phenotype	phenotype	NN
cord-010027-r0tl01kq	955	16	of	of	IN
cord-010027-r0tl01kq	955	17	dilated	dilated	JJ
cord-010027-r0tl01kq	955	18	and	and	CC
cord-010027-r0tl01kq	955	19	arrhythmogenic	arrhythmogenic	JJ
cord-010027-r0tl01kq	955	20	cardiomyopathy	cardiomyopathy	NN
cord-010027-r0tl01kq	955	21	were	be	VBD
cord-010027-r0tl01kq	955	22	included	include	VBN
cord-010027-r0tl01kq	955	23	.	.	.
cord-010027-r0tl01kq	956	1	Microscopic	microscopic	JJ
cord-010027-r0tl01kq	956	2	slices	slice	NNS
cord-010027-r0tl01kq	956	3	from	from	IN
cord-010027-r0tl01kq	956	4	8	8	CD
cord-010027-r0tl01kq	956	5	regions	region	NNS
cord-010027-r0tl01kq	956	6	were	be	VBD
cord-010027-r0tl01kq	956	7	immunohistochemically	immunohistochemically	RB
cord-010027-r0tl01kq	956	8	stained	stain	VBN
cord-010027-r0tl01kq	956	9	for	for	IN
cord-010027-r0tl01kq	956	10	P62	P62	NNP
cord-010027-r0tl01kq	956	11	,	,	,
cord-010027-r0tl01kq	956	12	a	a	DT
cord-010027-r0tl01kq	956	13	marker	marker	NN
cord-010027-r0tl01kq	956	14	for	for	IN
cord-010027-r0tl01kq	956	15	aggregated	aggregated	JJ
cord-010027-r0tl01kq	956	16	proteins	protein	NNS
cord-010027-r0tl01kq	956	17	destined	destine	VBN
cord-010027-r0tl01kq	956	18	for	for	IN
cord-010027-r0tl01kq	956	19	autophagy	autophagy	NN
cord-010027-r0tl01kq	956	20	.	.	.
cord-010027-r0tl01kq	957	1	Results	result	NNS
cord-010027-r0tl01kq	957	2	:	:	:
cord-010027-r0tl01kq	958	1	Sporadic	sporadic	JJ
cord-010027-r0tl01kq	958	2	P62	P62	NNP
cord-010027-r0tl01kq	958	3	positive	positive	JJ
cord-010027-r0tl01kq	958	4	cells	cell	NNS
cord-010027-r0tl01kq	958	5	were	be	VBD
cord-010027-r0tl01kq	958	6	seen	see	VBN
cord-010027-r0tl01kq	958	7	in	in	IN
cord-010027-r0tl01kq	958	8	control	control	NN
cord-010027-r0tl01kq	958	9	hearts	heart	NNS
cord-010027-r0tl01kq	958	10	(	(	-LRB-
cord-010027-r0tl01kq	958	11	0.5	0.5	CD
cord-010027-r0tl01kq	958	12	%	%	NN
cord-010027-r0tl01kq	958	13	of	of	IN
cord-010027-r0tl01kq	958	14	cardiomyocytes	cardiomyocyte	NNS
cord-010027-r0tl01kq	958	15	,	,	,
cord-010027-r0tl01kq	958	16	range	range	VBP
cord-010027-r0tl01kq	958	17	0.1	0.1	CD
cord-010027-r0tl01kq	958	18	-	-	HYPH
cord-010027-r0tl01kq	958	19	0.8	0.8	CD
cord-010027-r0tl01kq	958	20	%	%	NN
cord-010027-r0tl01kq	958	21	)	)	-RRB-
cord-010027-r0tl01kq	958	22	.	.	.
cord-010027-r0tl01kq	959	1	Troponin	troponin	JJ
cord-010027-r0tl01kq	959	2	mutations	mutation	NNS
cord-010027-r0tl01kq	959	3	(	(	-LRB-
cord-010027-r0tl01kq	959	4	TNNT2	TNNT2	NNP
cord-010027-r0tl01kq	959	5	and	and	CC
cord-010027-r0tl01kq	959	6	TNNI3	TNNI3	NNP
cord-010027-r0tl01kq	959	7	;	;	:
cord-010027-r0tl01kq	959	8	0.7	0.7	CD
cord-010027-r0tl01kq	959	9	%	%	NN
cord-010027-r0tl01kq	959	10	,	,	,
cord-010027-r0tl01kq	959	11	range	range	VBP
cord-010027-r0tl01kq	959	12	0.2	0.2	CD
cord-010027-r0tl01kq	959	13	-	-	SYM
cord-010027-r0tl01kq	959	14	1.2	1.2	CD
cord-010027-r0tl01kq	959	15	%	%	NN
cord-010027-r0tl01kq	959	16	,	,	,
cord-010027-r0tl01kq	959	17	n=3	n=3	NN
cord-010027-r0tl01kq	959	18	)	)	-RRB-
cord-010027-r0tl01kq	959	19	showed	show	VBD
cord-010027-r0tl01kq	959	20	hardly	hardly	RB
cord-010027-r0tl01kq	959	21	any	any	DT
cord-010027-r0tl01kq	959	22	increase	increase	NN
cord-010027-r0tl01kq	959	23	in	in	IN
cord-010027-r0tl01kq	959	24	P62	P62	NNP
cord-010027-r0tl01kq	959	25	.	.	.
cord-010027-r0tl01kq	960	1	Titin	Titin	NNP
cord-010027-r0tl01kq	960	2	(	(	-LRB-
cord-010027-r0tl01kq	960	3	1.6	1.6	CD
cord-010027-r0tl01kq	960	4	%	%	NN
cord-010027-r0tl01kq	960	5	,	,	,
cord-010027-r0tl01kq	960	6	range	range	VBP
cord-010027-r0tl01kq	960	7	0.7	0.7	CD
cord-010027-r0tl01kq	960	8	-	-	HYPH
cord-010027-r0tl01kq	960	9	2.7	2.7	CD
cord-010027-r0tl01kq	960	10	%	%	NN
cord-010027-r0tl01kq	960	11	,	,	,
cord-010027-r0tl01kq	960	12	n=5	n=5	JJ
cord-010027-r0tl01kq	960	13	)	)	-RRB-
cord-010027-r0tl01kq	960	14	and	and	CC
cord-010027-r0tl01kq	961	1	lamin	lamin	NNP
cord-010027-r0tl01kq	961	2	A	A	NNP
cord-010027-r0tl01kq	961	3	/	/	SYM
cord-010027-r0tl01kq	961	4	C	C	NNP
cord-010027-r0tl01kq	961	5	(	(	-LRB-
cord-010027-r0tl01kq	961	6	1.7	1.7	CD
cord-010027-r0tl01kq	961	7	%	%	NN
cord-010027-r0tl01kq	961	8	,	,	,
cord-010027-r0tl01kq	961	9	range	range	VBP
cord-010027-r0tl01kq	961	10	1.1	1.1	CD
cord-010027-r0tl01kq	961	11	-	-	SYM
cord-010027-r0tl01kq	961	12	2.5	2.5	CD
cord-010027-r0tl01kq	961	13	%	%	NN
cord-010027-r0tl01kq	961	14	,	,	,
cord-010027-r0tl01kq	961	15	n=5	n=5	JJ
cord-010027-r0tl01kq	961	16	)	)	-RRB-
cord-010027-r0tl01kq	961	17	mutations	mutation	NNS
cord-010027-r0tl01kq	961	18	showed	show	VBD
cord-010027-r0tl01kq	961	19	a	a	DT
cord-010027-r0tl01kq	961	20	threefold	threefold	JJ
cord-010027-r0tl01kq	961	21	increase	increase	NN
cord-010027-r0tl01kq	961	22	in	in	IN
cord-010027-r0tl01kq	961	23	P62	P62	NNP
cord-010027-r0tl01kq	961	24	staining	staining	NN
cord-010027-r0tl01kq	961	25	.	.	.
cord-010027-r0tl01kq	962	1	A	a	DT
cord-010027-r0tl01kq	962	2	tenfold	tenfold	RB
cord-010027-r0tl01kq	962	3	positive	positive	JJ
cord-010027-r0tl01kq	962	4	staining	staining	NN
cord-010027-r0tl01kq	962	5	was	be	VBD
cord-010027-r0tl01kq	962	6	found	find	VBN
cord-010027-r0tl01kq	962	7	in	in	IN
cord-010027-r0tl01kq	962	8	desmosomal	desmosomal	JJ
cord-010027-r0tl01kq	962	9	mutations	mutation	NNS
cord-010027-r0tl01kq	962	10	(	(	-LRB-
cord-010027-r0tl01kq	962	11	PKP2	PKP2	NNP
cord-010027-r0tl01kq	962	12	and	and	CC
cord-010027-r0tl01kq	962	13	DSP	DSP	NNP
cord-010027-r0tl01kq	962	14	;	;	:
cord-010027-r0tl01kq	962	15	3.8	3.8	CD
cord-010027-r0tl01kq	962	16	%	%	NN
cord-010027-r0tl01kq	962	17	,	,	,
cord-010027-r0tl01kq	962	18	range	range	VBP
cord-010027-r0tl01kq	962	19	3.7	3.7	CD
cord-010027-r0tl01kq	962	20	-	-	SYM
cord-010027-r0tl01kq	962	21	4.0	4.0	CD
cord-010027-r0tl01kq	962	22	%	%	NN
cord-010027-r0tl01kq	962	23	,	,	,
cord-010027-r0tl01kq	962	24	n=3	n=3	NN
cord-010027-r0tl01kq	962	25	)	)	-RRB-
cord-010027-r0tl01kq	962	26	and	and	CC
cord-010027-r0tl01kq	962	27	myosin	myosin	NN
cord-010027-r0tl01kq	962	28	mutations	mutation	NNS
cord-010027-r0tl01kq	962	29	(	(	-LRB-
cord-010027-r0tl01kq	962	30	MYH7	MYH7	NNP
cord-010027-r0tl01kq	962	31	and	and	CC
cord-010027-r0tl01kq	962	32	MYBPC3	mybpc3	NN
cord-010027-r0tl01kq	962	33	;	;	:
cord-010027-r0tl01kq	962	34	4,6	4,6	CD
cord-010027-r0tl01kq	962	35	%	%	NN
cord-010027-r0tl01kq	962	36	range	range	NN
cord-010027-r0tl01kq	962	37	3.3	3.3	CD
cord-010027-r0tl01kq	962	38	-	-	SYM
cord-010027-r0tl01kq	962	39	5.7	5.7	CD
cord-010027-r0tl01kq	962	40	%	%	NN
cord-010027-r0tl01kq	962	41	,	,	,
cord-010027-r0tl01kq	962	42	n=3	n=3	NN
cord-010027-r0tl01kq	962	43	)	)	-RRB-
cord-010027-r0tl01kq	962	44	.	.	.
cord-010027-r0tl01kq	963	1	Phospholamban	Phospholamban	NNP
cord-010027-r0tl01kq	963	2	mutations	mutation	NNS
cord-010027-r0tl01kq	963	3	(	(	-LRB-
cord-010027-r0tl01kq	963	4	8.8	8.8	CD
cord-010027-r0tl01kq	963	5	%	%	NN
cord-010027-r0tl01kq	963	6	,	,	,
cord-010027-r0tl01kq	963	7	range	range	VBP
cord-010027-r0tl01kq	963	8	4.1	4.1	CD
cord-010027-r0tl01kq	963	9	-	-	SYM
cord-010027-r0tl01kq	963	10	16	16	CD
cord-010027-r0tl01kq	963	11	%	%	NN
cord-010027-r0tl01kq	963	12	,	,	,
cord-010027-r0tl01kq	963	13	n=8	n=8	NN
cord-010027-r0tl01kq	963	14	)	)	-RRB-
cord-010027-r0tl01kq	963	15	and	and	CC
cord-010027-r0tl01kq	963	16	desminopathies	desminopathie	NNS
cord-010027-r0tl01kq	963	17	(	(	-LRB-
cord-010027-r0tl01kq	963	18	desmin	desmin	NNP
cord-010027-r0tl01kq	963	19	and	and	CC
cord-010027-r0tl01kq	963	20	Alpha	Alpha	NNP
cord-010027-r0tl01kq	963	21	-	-	HYPH
cord-010027-r0tl01kq	963	22	B	b	NN
cord-010027-r0tl01kq	963	23	crystallin	crystallin	NNP
cord-010027-r0tl01kq	963	24	;	;	:
cord-010027-r0tl01kq	963	25	17	17	CD
cord-010027-r0tl01kq	963	26	%	%	NN
cord-010027-r0tl01kq	963	27	of	of	IN
cord-010027-r0tl01kq	963	28	cardiomyocytes	cardiomyocyte	NNS
cord-010027-r0tl01kq	963	29	,	,	,
cord-010027-r0tl01kq	963	30	range	range	VBP
cord-010027-r0tl01kq	963	31	4.0	4.0	CD
cord-010027-r0tl01kq	963	32	-	-	SYM
cord-010027-r0tl01kq	963	33	31	31	CD
cord-010027-r0tl01kq	963	34	%	%	NN
cord-010027-r0tl01kq	963	35	,	,	,
cord-010027-r0tl01kq	963	36	n=3	n=3	NN
cord-010027-r0tl01kq	963	37	)	)	-RRB-
cord-010027-r0tl01kq	963	38	showed	show	VBD
cord-010027-r0tl01kq	963	39	the	the	DT
cord-010027-r0tl01kq	963	40	highest	high	JJS
cord-010027-r0tl01kq	963	41	number	number	NN
cord-010027-r0tl01kq	963	42	of	of	IN
cord-010027-r0tl01kq	963	43	P62	P62	NNP
cord-010027-r0tl01kq	963	44	positive	positive	JJ
cord-010027-r0tl01kq	963	45	cells	cell	NNS
cord-010027-r0tl01kq	963	46	.	.	.
cord-010027-r0tl01kq	964	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	964	2	:	:	:
cord-010027-r0tl01kq	965	1	Accumulation	accumulation	NN
cord-010027-r0tl01kq	965	2	of	of	IN
cord-010027-r0tl01kq	965	3	P62	P62	NNP
cord-010027-r0tl01kq	965	4	positive	positive	JJ
cord-010027-r0tl01kq	965	5	protein	protein	NN
cord-010027-r0tl01kq	965	6	aggregates	aggregate	NNS
cord-010027-r0tl01kq	965	7	is	be	VBZ
cord-010027-r0tl01kq	965	8	associated	associate	VBN
cord-010027-r0tl01kq	965	9	with	with	IN
cord-010027-r0tl01kq	965	10	the	the	DT
cord-010027-r0tl01kq	965	11	type	type	NN
cord-010027-r0tl01kq	965	12	of	of	IN
cord-010027-r0tl01kq	965	13	mutation	mutation	NN
cord-010027-r0tl01kq	965	14	underlying	underlie	VBG
cord-010027-r0tl01kq	965	15	the	the	DT
cord-010027-r0tl01kq	965	16	dilated	dilated	JJ
cord-010027-r0tl01kq	965	17	cardiomyopathy	cardiomyopathy	NN
cord-010027-r0tl01kq	965	18	.	.	.
cord-010027-r0tl01kq	966	1	Titin	Titin	NNP
cord-010027-r0tl01kq	966	2	,	,	,
cord-010027-r0tl01kq	966	3	lamin	lamin	NN
cord-010027-r0tl01kq	966	4	A	A	NNP
cord-010027-r0tl01kq	966	5	/	/	SYM
cord-010027-r0tl01kq	966	6	C	c	NN
cord-010027-r0tl01kq	966	7	and	and	CC
cord-010027-r0tl01kq	966	8	troponin	troponin	JJ
cord-010027-r0tl01kq	966	9	mutations	mutation	NNS
cord-010027-r0tl01kq	966	10	revealed	reveal	VBD
cord-010027-r0tl01kq	966	11	little	little	JJ
cord-010027-r0tl01kq	966	12	protein	protein	NN
cord-010027-r0tl01kq	966	13	aggregation	aggregation	NN
cord-010027-r0tl01kq	966	14	,	,	,
cord-010027-r0tl01kq	966	15	whereas	whereas	IN
cord-010027-r0tl01kq	966	16	desminopathies	desminopathie	NNS
cord-010027-r0tl01kq	966	17	,	,	,
cord-010027-r0tl01kq	966	18	phospholamban	phospholamban	NNP
cord-010027-r0tl01kq	966	19	,	,	,
cord-010027-r0tl01kq	966	20	desmosomal	desmosomal	NNP
cord-010027-r0tl01kq	966	21	and	and	CC
cord-010027-r0tl01kq	966	22	myosin	myosin	NNS
cord-010027-r0tl01kq	966	23	mutations	mutation	NNS
cord-010027-r0tl01kq	966	24	show	show	VBP
cord-010027-r0tl01kq	966	25	abundant	abundant	JJ
cord-010027-r0tl01kq	966	26	aggregates	aggregate	NNS
cord-010027-r0tl01kq	966	27	.	.	.
cord-010027-r0tl01kq	967	1	This	this	DT
cord-010027-r0tl01kq	967	2	suggests	suggest	VBZ
cord-010027-r0tl01kq	967	3	that	that	IN
cord-010027-r0tl01kq	967	4	the	the	DT
cord-010027-r0tl01kq	967	5	type	type	NN
cord-010027-r0tl01kq	967	6	of	of	IN
cord-010027-r0tl01kq	967	7	mutation	mutation	NN
cord-010027-r0tl01kq	967	8	plays	play	VBZ
cord-010027-r0tl01kq	967	9	an	an	DT
cord-010027-r0tl01kq	967	10	important	important	JJ
cord-010027-r0tl01kq	967	11	role	role	NN
cord-010027-r0tl01kq	967	12	in	in	IN
cord-010027-r0tl01kq	967	13	determining	determine	VBG
cord-010027-r0tl01kq	967	14	distinct	distinct	JJ
cord-010027-r0tl01kq	967	15	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	967	16	of	of	IN
cord-010027-r0tl01kq	967	17	cardiomyocyte	cardiomyocyte	NNP
cord-010027-r0tl01kq	967	18	cell	cell	NN
cord-010027-r0tl01kq	967	19	death	death	NN
cord-010027-r0tl01kq	967	20	.	.	.
cord-010027-r0tl01kq	968	1	Major	Major	NNP
cord-010027-r0tl01kq	968	2	Trauma	Trauma	NNP
cord-010027-r0tl01kq	968	3	Centre	Centre	NNP
cord-010027-r0tl01kq	968	4	Status	Status	NNP
cord-010027-r0tl01kq	968	5	and	and	CC
cord-010027-r0tl01kq	968	6	its	-PRON-	PRP$
cord-010027-r0tl01kq	968	7	Impact	Impact	NNP
cord-010027-r0tl01kq	968	8	on	on	IN
cord-010027-r0tl01kq	968	9	the	the	DT
cord-010027-r0tl01kq	968	10	Department	Department	NNP
cord-010027-r0tl01kq	968	11	of	of	IN
cord-010027-r0tl01kq	968	12	Cellular	Cellular	NNP
cord-010027-r0tl01kq	968	13	and	and	CC
cord-010027-r0tl01kq	968	14	Anatomical	Anatomical	NNP
cord-010027-r0tl01kq	968	15	Pathology	Pathology	NNP
cord-010027-r0tl01kq	968	16	in	in	IN
cord-010027-r0tl01kq	968	17	a	a	DT
cord-010027-r0tl01kq	968	18	large	large	JJ
cord-010027-r0tl01kq	968	19	Tertiary	Tertiary	NNP
cord-010027-r0tl01kq	968	20	Referral	Referral	NNP
cord-010027-r0tl01kq	968	21	Centre	Centre	NNP
cord-010027-r0tl01kq	968	22	P	P	NNP
cord-010027-r0tl01kq	968	23	RA	RA	NNP
cord-010027-r0tl01kq	968	24	Hadden	Hadden	NNP
cord-010027-r0tl01kq	968	25	Background	Background	NNP
cord-010027-r0tl01kq	968	26	:	:	:
cord-010027-r0tl01kq	968	27	Major	Major	NNP
cord-010027-r0tl01kq	968	28	Trauma	Trauma	NNP
cord-010027-r0tl01kq	968	29	has	have	VBZ
cord-010027-r0tl01kq	968	30	been	be	VBN
cord-010027-r0tl01kq	968	31	centralised	centralise	VBN
cord-010027-r0tl01kq	968	32	into	into	IN
cord-010027-r0tl01kq	968	33	Major	Major	NNP
cord-010027-r0tl01kq	968	34	Trauma	Trauma	NNP
cord-010027-r0tl01kq	968	35	Centres	Centres	NNPS
cord-010027-r0tl01kq	968	36	which	which	WDT
cord-010027-r0tl01kq	968	37	act	act	VBP
cord-010027-r0tl01kq	968	38	as	as	IN
cord-010027-r0tl01kq	968	39	the	the	DT
cord-010027-r0tl01kq	968	40	focus	focus	NN
cord-010027-r0tl01kq	968	41	of	of	IN
cord-010027-r0tl01kq	968	42	Major	Major	NNP
cord-010027-r0tl01kq	968	43	Trauma	Trauma	NNP
cord-010027-r0tl01kq	968	44	Networks	Networks	NNPS
cord-010027-r0tl01kq	968	45	.	.	.
cord-010027-r0tl01kq	969	1	In	in	IN
cord-010027-r0tl01kq	969	2	April	April	NNP
cord-010027-r0tl01kq	969	3	2012	2012	CD
cord-010027-r0tl01kq	969	4	,	,	,
cord-010027-r0tl01kq	969	5	Derriford	Derriford	NNP
cord-010027-r0tl01kq	969	6	Hospital	Hospital	NNP
cord-010027-r0tl01kq	969	7	in	in	IN
cord-010027-r0tl01kq	969	8	Plymouth	Plymouth	NNP
cord-010027-r0tl01kq	969	9	,	,	,
cord-010027-r0tl01kq	969	10	Devon	Devon	NNP
cord-010027-r0tl01kq	969	11	became	become	VBD
cord-010027-r0tl01kq	969	12	operational	operational	JJ
cord-010027-r0tl01kq	969	13	as	as	IN
cord-010027-r0tl01kq	969	14	the	the	DT
cord-010027-r0tl01kq	969	15	regional	regional	JJ
cord-010027-r0tl01kq	969	16	Major	Major	NNP
cord-010027-r0tl01kq	969	17	Trauma	Trauma	NNP
cord-010027-r0tl01kq	969	18	Centre	Centre	NNP
cord-010027-r0tl01kq	969	19	for	for	IN
cord-010027-r0tl01kq	969	20	the	the	DT
cord-010027-r0tl01kq	969	21	South	South	NNP
cord-010027-r0tl01kq	969	22	West	West	NNP
cord-010027-r0tl01kq	969	23	Peninsula	Peninsula	NNP
cord-010027-r0tl01kq	969	24	.	.	.
cord-010027-r0tl01kq	970	1	As	as	IN
cord-010027-r0tl01kq	970	2	a	a	DT
cord-010027-r0tl01kq	970	3	result	result	NN
cord-010027-r0tl01kq	970	4	,	,	,
cord-010027-r0tl01kq	970	5	there	there	EX
cord-010027-r0tl01kq	970	6	was	be	VBD
cord-010027-r0tl01kq	970	7	potential	potential	JJ
cord-010027-r0tl01kq	970	8	for	for	IN
cord-010027-r0tl01kq	970	9	an	an	DT
cord-010027-r0tl01kq	970	10	increased	increase	VBN
cord-010027-r0tl01kq	970	11	number	number	NN
cord-010027-r0tl01kq	970	12	of	of	IN
cord-010027-r0tl01kq	970	13	trauma	trauma	NN
cord-010027-r0tl01kq	970	14	-	-	HYPH
cord-010027-r0tl01kq	970	15	related	relate	VBN
cord-010027-r0tl01kq	970	16	deaths	death	NNS
cord-010027-r0tl01kq	970	17	to	to	TO
cord-010027-r0tl01kq	970	18	be	be	VB
cord-010027-r0tl01kq	970	19	referred	refer	VBN
cord-010027-r0tl01kq	970	20	to	to	IN
cord-010027-r0tl01kq	970	21	the	the	DT
cord-010027-r0tl01kq	970	22	local	local	JJ
cord-010027-r0tl01kq	970	23	coroner	coroner	NN
cord-010027-r0tl01kq	970	24	,	,	,
cord-010027-r0tl01kq	970	25	as	as	RB
cord-010027-r0tl01kq	970	26	well	well	RB
cord-010027-r0tl01kq	970	27	as	as	IN
cord-010027-r0tl01kq	970	28	surgical	surgical	JJ
cord-010027-r0tl01kq	970	29	specimens	specimen	NNS
cord-010027-r0tl01kq	970	30	,	,	,
cord-010027-r0tl01kq	970	31	potentially	potentially	RB
cord-010027-r0tl01kq	970	32	increasing	increase	VBG
cord-010027-r0tl01kq	970	33	the	the	DT
cord-010027-r0tl01kq	970	34	work	work	NN
cord-010027-r0tl01kq	970	35	load	load	NN
cord-010027-r0tl01kq	970	36	on	on	IN
cord-010027-r0tl01kq	970	37	pathologists	pathologist	NNS
cord-010027-r0tl01kq	970	38	.	.	.
cord-010027-r0tl01kq	971	1	The	the	DT
cord-010027-r0tl01kq	971	2	case	case	NN
cord-010027-r0tl01kq	971	3	mix	mix	NN
cord-010027-r0tl01kq	971	4	could	could	MD
cord-010027-r0tl01kq	971	5	include	include	VB
cord-010027-r0tl01kq	971	6	post	post	JJ
cord-010027-r0tl01kq	971	7	-	-	JJ
cord-010027-r0tl01kq	971	8	operative	operative	JJ
cord-010027-r0tl01kq	971	9	cases	case	NNS
cord-010027-r0tl01kq	971	10	,	,	,
cord-010027-r0tl01kq	971	11	neurosurgical	neurosurgical	JJ
cord-010027-r0tl01kq	971	12	cases	case	NNS
cord-010027-r0tl01kq	971	13	,	,	,
cord-010027-r0tl01kq	971	14	polytrauma	polytrauma	NN
cord-010027-r0tl01kq	971	15	cases	case	NNS
cord-010027-r0tl01kq	971	16	and	and	CC
cord-010027-r0tl01kq	971	17	forensic	forensic	JJ
cord-010027-r0tl01kq	971	18	cases	case	NNS
cord-010027-r0tl01kq	971	19	.	.	.
cord-010027-r0tl01kq	972	1	Methods	method	NNS
cord-010027-r0tl01kq	972	2	:	:	:
cord-010027-r0tl01kq	973	1	On	on	IN
cord-010027-r0tl01kq	973	2	admission	admission	NN
cord-010027-r0tl01kq	973	3	,	,	,
cord-010027-r0tl01kq	973	4	all	all	DT
cord-010027-r0tl01kq	973	5	eligible	eligible	JJ
cord-010027-r0tl01kq	973	6	trauma	trauma	NN
cord-010027-r0tl01kq	973	7	patients	patient	NNS
cord-010027-r0tl01kq	973	8	are	be	VBP
cord-010027-r0tl01kq	973	9	recorded	record	VBN
cord-010027-r0tl01kq	973	10	onto	onto	IN
cord-010027-r0tl01kq	973	11	the	the	DT
cord-010027-r0tl01kq	973	12	Trauma	Trauma	NNP
cord-010027-r0tl01kq	973	13	Audit	Audit	NNP
cord-010027-r0tl01kq	973	14	&	&	CC
cord-010027-r0tl01kq	973	15	Research	Research	NNP
cord-010027-r0tl01kq	973	16	Network	Network	NNP
cord-010027-r0tl01kq	973	17	(	(	-LRB-
cord-010027-r0tl01kq	973	18	TARN	TARN	NNP
cord-010027-r0tl01kq	973	19	)	)	-RRB-
cord-010027-r0tl01kq	973	20	database	database	NN
cord-010027-r0tl01kq	973	21	.	.	.
cord-010027-r0tl01kq	974	1	The	the	DT
cord-010027-r0tl01kq	974	2	TARN	TARN	NNP
cord-010027-r0tl01kq	974	3	data	datum	NNS
cord-010027-r0tl01kq	974	4	was	be	VBD
cord-010027-r0tl01kq	974	5	retrospectively	retrospectively	RB
cord-010027-r0tl01kq	974	6	analysed	analyse	VBN
cord-010027-r0tl01kq	974	7	and	and	CC
cord-010027-r0tl01kq	974	8	cross	cross	NN
cord-010027-r0tl01kq	974	9	referenced	reference	VBN
cord-010027-r0tl01kq	974	10	with	with	IN
cord-010027-r0tl01kq	974	11	the	the	DT
cord-010027-r0tl01kq	974	12	Department	Department	NNP
cord-010027-r0tl01kq	974	13	of	of	IN
cord-010027-r0tl01kq	974	14	Cellular	Cellular	NNP
cord-010027-r0tl01kq	974	15	and	and	CC
cord-010027-r0tl01kq	974	16	Anatomical	Anatomical	NNP
cord-010027-r0tl01kq	974	17	Pathologies	Pathologies	NNPS
cord-010027-r0tl01kq	974	18	database	database	NN
cord-010027-r0tl01kq	974	19	to	to	TO
cord-010027-r0tl01kq	974	20	determine	determine	VB
cord-010027-r0tl01kq	974	21	how	how	WRB
cord-010027-r0tl01kq	974	22	many	many	JJ
cord-010027-r0tl01kq	974	23	patients	patient	NNS
cord-010027-r0tl01kq	974	24	had	have	VBD
cord-010027-r0tl01kq	974	25	died	die	VBN
cord-010027-r0tl01kq	974	26	,	,	,
cord-010027-r0tl01kq	974	27	how	how	WRB
cord-010027-r0tl01kq	974	28	many	many	JJ
cord-010027-r0tl01kq	974	29	had	have	VBD
cord-010027-r0tl01kq	974	30	post	post	JJ
cord-010027-r0tl01kq	974	31	-	-	JJ
cord-010027-r0tl01kq	974	32	mortem	mortem	JJ
cord-010027-r0tl01kq	974	33	examinations	examination	NNS
cord-010027-r0tl01kq	974	34	were	be	VBD
cord-010027-r0tl01kq	974	35	performed	perform	VBN
cord-010027-r0tl01kq	974	36	and	and	CC
cord-010027-r0tl01kq	974	37	how	how	WRB
cord-010027-r0tl01kq	974	38	many	many	JJ
cord-010027-r0tl01kq	974	39	surgical	surgical	JJ
cord-010027-r0tl01kq	974	40	specimens	specimen	NNS
cord-010027-r0tl01kq	974	41	were	be	VBD
cord-010027-r0tl01kq	974	42	sent	send	VBN
cord-010027-r0tl01kq	974	43	,	,	,
cord-010027-r0tl01kq	974	44	on	on	IN
cord-010027-r0tl01kq	974	45	patients	patient	NNS
cord-010027-r0tl01kq	974	46	from	from	IN
cord-010027-r0tl01kq	974	47	outside	outside	IN
cord-010027-r0tl01kq	974	48	the	the	DT
cord-010027-r0tl01kq	974	49	region	region	NN
cord-010027-r0tl01kq	974	50	or	or	CC
cord-010027-r0tl01kq	974	51	transferred	transfer	VBN
cord-010027-r0tl01kq	974	52	from	from	IN
cord-010027-r0tl01kq	974	53	smaller	small	JJR
cord-010027-r0tl01kq	974	54	Major	Major	NNP
cord-010027-r0tl01kq	974	55	Trauma	Trauma	NNP
cord-010027-r0tl01kq	974	56	Units	Units	NNPS
cord-010027-r0tl01kq	974	57	.	.	.
cord-010027-r0tl01kq	975	1	Results	result	NNS
cord-010027-r0tl01kq	975	2	:	:	:
cord-010027-r0tl01kq	976	1	Over	over	IN
cord-010027-r0tl01kq	976	2	the	the	DT
cord-010027-r0tl01kq	976	3	first	first	JJ
cord-010027-r0tl01kq	976	4	two	two	CD
cord-010027-r0tl01kq	976	5	years	year	NNS
cord-010027-r0tl01kq	976	6	,	,	,
cord-010027-r0tl01kq	976	7	there	there	EX
cord-010027-r0tl01kq	976	8	was	be	VBD
cord-010027-r0tl01kq	976	9	a	a	DT
cord-010027-r0tl01kq	976	10	small	small	JJ
cord-010027-r0tl01kq	976	11	increase	increase	NN
cord-010027-r0tl01kq	976	12	in	in	IN
cord-010027-r0tl01kq	976	13	workload	workload	NN
cord-010027-r0tl01kq	976	14	from	from	IN
cord-010027-r0tl01kq	976	15	patients	patient	NNS
cord-010027-r0tl01kq	976	16	who	who	WP
cord-010027-r0tl01kq	976	17	,	,	,
cord-010027-r0tl01kq	976	18	prior	prior	RB
cord-010027-r0tl01kq	976	19	to	to	IN
cord-010027-r0tl01kq	976	20	Trauma	Trauma	NNP
cord-010027-r0tl01kq	976	21	Centre	Centre	NNP
cord-010027-r0tl01kq	976	22	status	status	NN
cord-010027-r0tl01kq	976	23	would	would	MD
cord-010027-r0tl01kq	976	24	have	have	VB
cord-010027-r0tl01kq	976	25	gone	go	VBN
cord-010027-r0tl01kq	976	26	to	to	IN
cord-010027-r0tl01kq	976	27	other	other	JJ
cord-010027-r0tl01kq	976	28	centres	centre	NNS
cord-010027-r0tl01kq	976	29	.	.	.
cord-010027-r0tl01kq	977	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	977	2	:	:	:
cord-010027-r0tl01kq	978	1	In	in	IN
cord-010027-r0tl01kq	978	2	recieveing	recievee	VBG
cord-010027-r0tl01kq	978	3	patients	patient	NNS
cord-010027-r0tl01kq	978	4	from	from	IN
cord-010027-r0tl01kq	978	5	elsewhere	elsewhere	RB
cord-010027-r0tl01kq	978	6	in	in	IN
cord-010027-r0tl01kq	978	7	the	the	DT
cord-010027-r0tl01kq	978	8	region	region	NN
cord-010027-r0tl01kq	978	9	,	,	,
cord-010027-r0tl01kq	978	10	there	there	EX
cord-010027-r0tl01kq	978	11	was	be	VBD
cord-010027-r0tl01kq	978	12	an	an	DT
cord-010027-r0tl01kq	978	13	increase	increase	NN
cord-010027-r0tl01kq	978	14	in	in	IN
cord-010027-r0tl01kq	978	15	workload	workload	NN
cord-010027-r0tl01kq	978	16	for	for	IN
cord-010027-r0tl01kq	978	17	both	both	DT
cord-010027-r0tl01kq	978	18	autopsy	autopsy	JJ
cord-010027-r0tl01kq	978	19	and	and	CC
cord-010027-r0tl01kq	978	20	non	non	JJ
cord-010027-r0tl01kq	978	21	-	-	JJ
cord-010027-r0tl01kq	978	22	autopsy	autopsy	JJ
cord-010027-r0tl01kq	978	23	work	work	NN
cord-010027-r0tl01kq	978	24	.	.	.
cord-010027-r0tl01kq	979	1	This	this	DT
cord-010027-r0tl01kq	979	2	excluded	exclude	VBD
cord-010027-r0tl01kq	979	3	some	some	DT
cord-010027-r0tl01kq	979	4	neurosurgical	neurosurgical	JJ
cord-010027-r0tl01kq	979	5	cases	case	NNS
cord-010027-r0tl01kq	979	6	,	,	,
cord-010027-r0tl01kq	979	7	which	which	WDT
cord-010027-r0tl01kq	979	8	traditionally	traditionally	RB
cord-010027-r0tl01kq	979	9	would	would	MD
cord-010027-r0tl01kq	979	10	have	have	VB
cord-010027-r0tl01kq	979	11	been	be	VBN
cord-010027-r0tl01kq	979	12	referred	refer	VBN
cord-010027-r0tl01kq	979	13	(	(	-LRB-
cord-010027-r0tl01kq	979	14	as	as	IN
cord-010027-r0tl01kq	979	15	Derriford	Derriford	NNP
cord-010027-r0tl01kq	979	16	is	be	VBZ
cord-010027-r0tl01kq	979	17	the	the	DT
cord-010027-r0tl01kq	979	18	neurosurgical	neurosurgical	JJ
cord-010027-r0tl01kq	979	19	centre	centre	NN
cord-010027-r0tl01kq	979	20	)	)	-RRB-
cord-010027-r0tl01kq	979	21	.	.	.
cord-010027-r0tl01kq	980	1	There	there	EX
cord-010027-r0tl01kq	980	2	are	be	VBP
cord-010027-r0tl01kq	980	3	several	several	JJ
cord-010027-r0tl01kq	980	4	areas	area	NNS
cord-010027-r0tl01kq	980	5	for	for	IN
cord-010027-r0tl01kq	980	6	implication	implication	NN
cord-010027-r0tl01kq	980	7	including	include	VBG
cord-010027-r0tl01kq	980	8	,	,	,
cord-010027-r0tl01kq	980	9	APT	apt	JJ
cord-010027-r0tl01kq	980	10	time	time	NN
cord-010027-r0tl01kq	980	11	,	,	,
cord-010027-r0tl01kq	980	12	mortuary	mortuary	NN
cord-010027-r0tl01kq	980	13	space	space	NN
cord-010027-r0tl01kq	980	14	and	and	CC
cord-010027-r0tl01kq	980	15	non	non	JJ
cord-010027-r0tl01kq	980	16	-	-	JJ
cord-010027-r0tl01kq	980	17	autopsy	autopsy	JJ
cord-010027-r0tl01kq	980	18	surgical	surgical	JJ
cord-010027-r0tl01kq	980	19	work	work	NN
cord-010027-r0tl01kq	980	20	.	.	.
cord-010027-r0tl01kq	981	1	Although	although	IN
cord-010027-r0tl01kq	981	2	the	the	DT
cord-010027-r0tl01kq	981	3	workload	workload	NN
cord-010027-r0tl01kq	981	4	increase	increase	NN
cord-010027-r0tl01kq	981	5	is	be	VBZ
cord-010027-r0tl01kq	981	6	small	small	JJ
cord-010027-r0tl01kq	981	7	,	,	,
cord-010027-r0tl01kq	981	8	at	at	IN
cord-010027-r0tl01kq	981	9	a	a	DT
cord-010027-r0tl01kq	981	10	time	time	NN
cord-010027-r0tl01kq	981	11	when	when	WRB
cord-010027-r0tl01kq	981	12	services	service	NNS
cord-010027-r0tl01kq	981	13	are	be	VBP
cord-010027-r0tl01kq	981	14	being	be	VBG
cord-010027-r0tl01kq	981	15	stretched	stretch	VBN
cord-010027-r0tl01kq	981	16	it	-PRON-	PRP
cord-010027-r0tl01kq	981	17	is	be	VBZ
cord-010027-r0tl01kq	981	18	important	important	JJ
cord-010027-r0tl01kq	981	19	to	to	TO
cord-010027-r0tl01kq	981	20	ensure	ensure	VB
cord-010027-r0tl01kq	981	21	any	any	DT
cord-010027-r0tl01kq	981	22	increase	increase	NN
cord-010027-r0tl01kq	981	23	in	in	IN
cord-010027-r0tl01kq	981	24	work	work	NN
cord-010027-r0tl01kq	981	25	will	will	MD
cord-010027-r0tl01kq	981	26	not	not	RB
cord-010027-r0tl01kq	981	27	be	be	VB
cord-010027-r0tl01kq	981	28	the	the	DT
cord-010027-r0tl01kq	981	29	"	"	``
cord-010027-r0tl01kq	981	30	straw	straw	NN
cord-010027-r0tl01kq	981	31	that	that	WDT
cord-010027-r0tl01kq	981	32	broke	break	VBD
cord-010027-r0tl01kq	981	33	the	the	DT
cord-010027-r0tl01kq	981	34	camels	camel	NNS
cord-010027-r0tl01kq	981	35	back	back	RB
cord-010027-r0tl01kq	981	36	"	"	''
cord-010027-r0tl01kq	981	37	and	and	CC
cord-010027-r0tl01kq	981	38	can	can	MD
cord-010027-r0tl01kq	981	39	be	be	VB
cord-010027-r0tl01kq	981	40	dealt	deal	VBN
cord-010027-r0tl01kq	981	41	with	with	IN
cord-010027-r0tl01kq	981	42	accordingly	accordingly	RB
cord-010027-r0tl01kq	981	43	.	.	.
cord-010027-r0tl01kq	982	1	Derriford	Derriford	NNP
cord-010027-r0tl01kq	982	2	Hospital	Hospital	NNP
cord-010027-r0tl01kq	982	3	,	,	,
cord-010027-r0tl01kq	982	4	Plymouth	Plymouth	NNP
cord-010027-r0tl01kq	982	5	,	,	,
cord-010027-r0tl01kq	982	6	UK	UK	NNP
cord-010027-r0tl01kq	983	1	To	to	TO
cord-010027-r0tl01kq	983	2	attempt	attempt	VB
cord-010027-r0tl01kq	983	3	to	to	TO
cord-010027-r0tl01kq	983	4	streamline	streamline	VB
cord-010027-r0tl01kq	983	5	general	general	JJ
cord-010027-r0tl01kq	983	6	pathologist	pathologist	NN
cord-010027-r0tl01kq	983	7	's	's	POS
cord-010027-r0tl01kq	983	8	approach	approach	NN
cord-010027-r0tl01kq	983	9	to	to	IN
cord-010027-r0tl01kq	983	10	the	the	DT
cord-010027-r0tl01kq	983	11	investigation	investigation	NN
cord-010027-r0tl01kq	983	12	of	of	IN
cord-010027-r0tl01kq	983	13	potentially	potentially	RB
cord-010027-r0tl01kq	983	14	asbestos	asbestos	NN
cord-010027-r0tl01kq	983	15	-	-	HYPH
cord-010027-r0tl01kq	983	16	related	relate	VBN
cord-010027-r0tl01kq	983	17	deaths	death	NNS
cord-010027-r0tl01kq	983	18	Methods	method	NNS
cord-010027-r0tl01kq	983	19	Turnaround	Turnaround	NNP
cord-010027-r0tl01kq	983	20	times	time	NNS
cord-010027-r0tl01kq	983	21	,	,	,
cord-010027-r0tl01kq	983	22	tissue	tissue	NN
cord-010027-r0tl01kq	983	23	sampling	sampling	NN
cord-010027-r0tl01kq	983	24	protocol	protocol	NN
cord-010027-r0tl01kq	983	25	and	and	CC
cord-010027-r0tl01kq	983	26	frequency	frequency	NN
cord-010027-r0tl01kq	983	27	with	with	IN
cord-010027-r0tl01kq	983	28	which	which	WDT
cord-010027-r0tl01kq	983	29	samples	sample	NNS
cord-010027-r0tl01kq	983	30	were	be	VBD
cord-010027-r0tl01kq	983	31	sent	send	VBN
cord-010027-r0tl01kq	983	32	for	for	IN
cord-010027-r0tl01kq	983	33	formal	formal	JJ
cord-010027-r0tl01kq	983	34	fibre	fibre	NN
cord-010027-r0tl01kq	983	35	counts	count	NNS
cord-010027-r0tl01kq	983	36	was	be	VBD
cord-010027-r0tl01kq	983	37	investigated	investigate	VBN
cord-010027-r0tl01kq	983	38	for	for	IN
cord-010027-r0tl01kq	983	39	100	100	CD
cord-010027-r0tl01kq	983	40	consecutive	consecutive	JJ
cord-010027-r0tl01kq	983	41	coronial	coronial	JJ
cord-010027-r0tl01kq	983	42	autopsies	autopsy	NNS
cord-010027-r0tl01kq	983	43	at	at	IN
cord-010027-r0tl01kq	983	44	the	the	DT
cord-010027-r0tl01kq	983	45	author	author	NN
cord-010027-r0tl01kq	983	46	's	's	POS
cord-010027-r0tl01kq	983	47	institution	institution	NN
cord-010027-r0tl01kq	983	48	.	.	.
cord-010027-r0tl01kq	984	1	Colleagues	colleague	NNS
cord-010027-r0tl01kq	984	2	at	at	IN
cord-010027-r0tl01kq	984	3	other	other	JJ
cord-010027-r0tl01kq	984	4	institutions	institution	NNS
cord-010027-r0tl01kq	984	5	were	be	VBD
cord-010027-r0tl01kq	984	6	questioned	question	VBN
cord-010027-r0tl01kq	984	7	about	about	IN
cord-010027-r0tl01kq	984	8	their	-PRON-	PRP$
cord-010027-r0tl01kq	984	9	own	own	JJ
cord-010027-r0tl01kq	984	10	practice	practice	NN
cord-010027-r0tl01kq	984	11	when	when	WRB
cord-010027-r0tl01kq	984	12	investigating	investigate	VBG
cord-010027-r0tl01kq	984	13	cases	case	NNS
cord-010027-r0tl01kq	984	14	of	of	IN
cord-010027-r0tl01kq	984	15	potential	potential	JJ
cord-010027-r0tl01kq	984	16	asbestosis	asbestosis	NN
cord-010027-r0tl01kq	984	17	,	,	,
cord-010027-r0tl01kq	984	18	lung	lung	NN
cord-010027-r0tl01kq	984	19	cancer	cancer	NN
cord-010027-r0tl01kq	984	20	or	or	CC
cord-010027-r0tl01kq	984	21	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	984	22	.	.	.
cord-010027-r0tl01kq	985	1	The	the	DT
cord-010027-r0tl01kq	985	2	author	author	NN
cord-010027-r0tl01kq	985	3	found	find	VBD
cord-010027-r0tl01kq	985	4	no	no	DT
cord-010027-r0tl01kq	985	5	consensus	consensus	NN
cord-010027-r0tl01kq	985	6	in	in	IN
cord-010027-r0tl01kq	985	7	opinion	opinion	NN
cord-010027-r0tl01kq	985	8	on	on	IN
cord-010027-r0tl01kq	985	9	methods	method	NNS
cord-010027-r0tl01kq	985	10	of	of	IN
cord-010027-r0tl01kq	985	11	sampling	sampling	NN
cord-010027-r0tl01kq	985	12	of	of	IN
cord-010027-r0tl01kq	985	13	the	the	DT
cord-010027-r0tl01kq	985	14	lungs	lung	NNS
cord-010027-r0tl01kq	985	15	in	in	IN
cord-010027-r0tl01kq	985	16	potential	potential	JJ
cord-010027-r0tl01kq	985	17	asbestosis	asbestosis	NN
cord-010027-r0tl01kq	985	18	,	,	,
cord-010027-r0tl01kq	985	19	lung	lung	NN
cord-010027-r0tl01kq	985	20	cancer	cancer	NN
cord-010027-r0tl01kq	985	21	or	or	CC
cord-010027-r0tl01kq	985	22	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	985	23	.	.	.
cord-010027-r0tl01kq	986	1	The	the	DT
cord-010027-r0tl01kq	986	2	most	most	RBS
cord-010027-r0tl01kq	986	3	common	common	JJ
cord-010027-r0tl01kq	986	4	indication	indication	NN
cord-010027-r0tl01kq	986	5	for	for	IN
cord-010027-r0tl01kq	986	6	samples	sample	NNS
cord-010027-r0tl01kq	986	7	to	to	TO
cord-010027-r0tl01kq	986	8	be	be	VB
cord-010027-r0tl01kq	986	9	sent	send	VBN
cord-010027-r0tl01kq	986	10	for	for	IN
cord-010027-r0tl01kq	986	11	asbestos	asbestos	NN
cord-010027-r0tl01kq	986	12	fibre	fibre	NN
cord-010027-r0tl01kq	986	13	counts	count	NNS
cord-010027-r0tl01kq	986	14	was	be	VBD
cord-010027-r0tl01kq	986	15	for	for	IN
cord-010027-r0tl01kq	986	16	malignant	malignant	JJ
cord-010027-r0tl01kq	986	17	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	986	18	.	.	.
cord-010027-r0tl01kq	987	1	Sending	send	VBG
cord-010027-r0tl01kq	987	2	tissue	tissue	NN
cord-010027-r0tl01kq	987	3	for	for	IN
cord-010027-r0tl01kq	987	4	fibre	fibre	NN
cord-010027-r0tl01kq	987	5	counts	count	NNS
cord-010027-r0tl01kq	987	6	led	lead	VBN
cord-010027-r0tl01kq	987	7	to	to	IN
cord-010027-r0tl01kq	987	8	considerable	considerable	JJ
cord-010027-r0tl01kq	987	9	delays	delay	NNS
cord-010027-r0tl01kq	987	10	in	in	IN
cord-010027-r0tl01kq	987	11	the	the	DT
cord-010027-r0tl01kq	987	12	authorisation	authorisation	NN
cord-010027-r0tl01kq	987	13	of	of	IN
cord-010027-r0tl01kq	987	14	postmortem	postmortem	NN
cord-010027-r0tl01kq	987	15	reports	report	NNS
cord-010027-r0tl01kq	987	16	and	and	CC
cord-010027-r0tl01kq	987	17	to	to	IN
cord-010027-r0tl01kq	987	18	significant	significant	JJ
cord-010027-r0tl01kq	987	19	cost	cost	NN
cord-010027-r0tl01kq	987	20	implications	implication	NNS
cord-010027-r0tl01kq	987	21	.	.	.
cord-010027-r0tl01kq	988	1	The	the	DT
cord-010027-r0tl01kq	988	2	author	author	NN
cord-010027-r0tl01kq	988	3	presents	present	VBZ
cord-010027-r0tl01kq	988	4	a	a	DT
cord-010027-r0tl01kq	988	5	pragmatic	pragmatic	JJ
cord-010027-r0tl01kq	988	6	algorithmic	algorithmic	JJ
cord-010027-r0tl01kq	988	7	guide	guide	NN
cord-010027-r0tl01kq	988	8	to	to	IN
cord-010027-r0tl01kq	988	9	approaching	approach	VBG
cord-010027-r0tl01kq	988	10	potentially	potentially	RB
cord-010027-r0tl01kq	988	11	asbestosis	asbestosis	NN
cord-010027-r0tl01kq	988	12	-	-	HYPH
cord-010027-r0tl01kq	988	13	related	relate	VBN
cord-010027-r0tl01kq	988	14	deaths	death	NNS
cord-010027-r0tl01kq	988	15	with	with	IN
cord-010027-r0tl01kq	988	16	suggestions	suggestion	NNS
cord-010027-r0tl01kq	988	17	for	for	IN
cord-010027-r0tl01kq	988	18	sampling	sample	VBG
cord-010027-r0tl01kq	988	19	the	the	DT
cord-010027-r0tl01kq	988	20	lungs	lung	NNS
cord-010027-r0tl01kq	988	21	and	and	CC
cord-010027-r0tl01kq	988	22	tumour	tumour	NN
cord-010027-r0tl01kq	988	23	in	in	IN
cord-010027-r0tl01kq	988	24	all	all	DT
cord-010027-r0tl01kq	988	25	cases	case	NNS
cord-010027-r0tl01kq	988	26	.	.	.
cord-010027-r0tl01kq	989	1	In	in	IN
cord-010027-r0tl01kq	989	2	general	general	JJ
cord-010027-r0tl01kq	989	3	terms	term	NNS
cord-010027-r0tl01kq	989	4	,	,	,
cord-010027-r0tl01kq	989	5	malignant	malignant	JJ
cord-010027-r0tl01kq	989	6	mesothelioma	mesothelioma	NN
cord-010027-r0tl01kq	989	7	previously	previously	RB
cord-010027-r0tl01kq	989	8	confirmed	confirm	VBD
cord-010027-r0tl01kq	989	9	premortem	premortem	NNP
cord-010027-r0tl01kq	989	10	with	with	IN
cord-010027-r0tl01kq	989	11	histology	histology	NN
cord-010027-r0tl01kq	989	12	and	and	CC
cord-010027-r0tl01kq	989	13	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	989	14	should	should	MD
cord-010027-r0tl01kq	989	15	not	not	RB
cord-010027-r0tl01kq	989	16	require	require	VB
cord-010027-r0tl01kq	989	17	extensive	extensive	JJ
cord-010027-r0tl01kq	989	18	postmortem	postmortem	JJ
cord-010027-r0tl01kq	989	19	histological	histological	JJ
cord-010027-r0tl01kq	989	20	sampling	sampling	NN
cord-010027-r0tl01kq	989	21	.	.	.
cord-010027-r0tl01kq	990	1	Lung	lung	NN
cord-010027-r0tl01kq	990	2	cancer	cancer	NN
cord-010027-r0tl01kq	990	3	and	and	CC
cord-010027-r0tl01kq	990	4	asbestosis	asbestosis	NN
cord-010027-r0tl01kq	990	5	require	require	VBP
cord-010027-r0tl01kq	990	6	widespread	widespread	JJ
cord-010027-r0tl01kq	990	7	sampling	sampling	NN
cord-010027-r0tl01kq	990	8	of	of	IN
cord-010027-r0tl01kq	990	9	lung	lung	NN
cord-010027-r0tl01kq	990	10	tissue	tissue	NN
cord-010027-r0tl01kq	990	11	to	to	TO
cord-010027-r0tl01kq	990	12	determine	determine	VB
cord-010027-r0tl01kq	990	13	amphibole	amphibole	NN
cord-010027-r0tl01kq	990	14	count	count	NN
cord-010027-r0tl01kq	990	15	according	accord	VBG
cord-010027-r0tl01kq	990	16	to	to	IN
cord-010027-r0tl01kq	990	17	Helsinki	Helsinki	NNP
cord-010027-r0tl01kq	990	18	criteria	criterion	NNS
cord-010027-r0tl01kq	990	19	in	in	IN
cord-010027-r0tl01kq	990	20	the	the	DT
cord-010027-r0tl01kq	990	21	former	former	JJ
cord-010027-r0tl01kq	990	22	,	,	,
cord-010027-r0tl01kq	990	23	and	and	CC
cord-010027-r0tl01kq	990	24	in	in	IN
cord-010027-r0tl01kq	990	25	the	the	DT
cord-010027-r0tl01kq	990	26	latter	latter	JJ
cord-010027-r0tl01kq	990	27	,	,	,
cord-010027-r0tl01kq	990	28	assessment	assessment	NN
cord-010027-r0tl01kq	990	29	of	of	IN
cord-010027-r0tl01kq	990	30	the	the	DT
cord-010027-r0tl01kq	990	31	distribution	distribution	NN
cord-010027-r0tl01kq	990	32	and	and	CC
cord-010027-r0tl01kq	990	33	degree	degree	NN
cord-010027-r0tl01kq	990	34	of	of	IN
cord-010027-r0tl01kq	990	35	fibrosis	fibrosis	NN
cord-010027-r0tl01kq	990	36	in	in	IN
cord-010027-r0tl01kq	990	37	addition	addition	NN
cord-010027-r0tl01kq	990	38	to	to	IN
cord-010027-r0tl01kq	990	39	fibre	fibre	NN
cord-010027-r0tl01kq	990	40	count	count	NN
cord-010027-r0tl01kq	990	41	.	.	.
cord-010027-r0tl01kq	991	1	One	one	CD
cord-010027-r0tl01kq	991	2	or	or	CC
cord-010027-r0tl01kq	991	3	more	more	JJR
cord-010027-r0tl01kq	991	4	of	of	IN
cord-010027-r0tl01kq	991	5	these	these	DT
cord-010027-r0tl01kq	991	6	tissue	tissue	NN
cord-010027-r0tl01kq	991	7	blocks	block	NNS
cord-010027-r0tl01kq	991	8	can	can	MD
cord-010027-r0tl01kq	991	9	be	be	VB
cord-010027-r0tl01kq	991	10	sent	send	VBN
cord-010027-r0tl01kq	991	11	for	for	IN
cord-010027-r0tl01kq	991	12	formal	formal	JJ
cord-010027-r0tl01kq	991	13	counts	count	NNS
cord-010027-r0tl01kq	991	14	in	in	IN
cord-010027-r0tl01kq	991	15	equivocal	equivocal	JJ
cord-010027-r0tl01kq	991	16	cases	case	NNS
cord-010027-r0tl01kq	991	17	after	after	IN
cord-010027-r0tl01kq	991	18	following	follow	VBG
cord-010027-r0tl01kq	991	19	the	the	DT
cord-010027-r0tl01kq	991	20	algorithmic	algorithmic	JJ
cord-010027-r0tl01kq	991	21	approach	approach	NN
cord-010027-r0tl01kq	991	22	.	.	.
cord-010027-r0tl01kq	992	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	993	1	Although	although	IN
cord-010027-r0tl01kq	993	2	predominantly	predominantly	RB
cord-010027-r0tl01kq	993	3	intended	intend	VBN
cord-010027-r0tl01kq	993	4	as	as	IN
cord-010027-r0tl01kq	993	5	a	a	DT
cord-010027-r0tl01kq	993	6	pragmatic	pragmatic	JJ
cord-010027-r0tl01kq	993	7	approach	approach	NN
cord-010027-r0tl01kq	993	8	to	to	TO
cord-010027-r0tl01kq	993	9	assist	assist	VB
cord-010027-r0tl01kq	993	10	the	the	DT
cord-010027-r0tl01kq	993	11	busy	busy	JJ
cord-010027-r0tl01kq	993	12	practicing	practice	VBG
cord-010027-r0tl01kq	993	13	autopsy	autopsy	JJ
cord-010027-r0tl01kq	993	14	pathologist	pathologist	NN
cord-010027-r0tl01kq	993	15	,	,	,
cord-010027-r0tl01kq	993	16	the	the	DT
cord-010027-r0tl01kq	993	17	author	author	NN
cord-010027-r0tl01kq	993	18	believes	believe	VBZ
cord-010027-r0tl01kq	993	19	that	that	IN
cord-010027-r0tl01kq	993	20	the	the	DT
cord-010027-r0tl01kq	993	21	algorithm	algorithm	NN
cord-010027-r0tl01kq	993	22	presented	present	VBN
cord-010027-r0tl01kq	993	23	will	will	MD
cord-010027-r0tl01kq	993	24	help	help	VB
cord-010027-r0tl01kq	993	25	departments	department	NNS
cord-010027-r0tl01kq	993	26	streamline	streamline	VB
cord-010027-r0tl01kq	993	27	their	-PRON-	PRP$
cord-010027-r0tl01kq	993	28	approach	approach	NN
cord-010027-r0tl01kq	993	29	to	to	IN
cord-010027-r0tl01kq	993	30	these	these	DT
cord-010027-r0tl01kq	993	31	cases	case	NNS
cord-010027-r0tl01kq	993	32	and	and	CC
cord-010027-r0tl01kq	993	33	help	help	VB
cord-010027-r0tl01kq	993	34	the	the	DT
cord-010027-r0tl01kq	993	35	relative	relative	NN
cord-010027-r0tl01kq	993	36	of	of	IN
cord-010027-r0tl01kq	993	37	the	the	DT
cord-010027-r0tl01kq	993	38	deceased	deceased	JJ
cord-010027-r0tl01kq	993	39	gain	gain	NN
cord-010027-r0tl01kq	993	40	access	access	NN
cord-010027-r0tl01kq	993	41	to	to	IN
cord-010027-r0tl01kq	993	42	compensation	compensation	NN
cord-010027-r0tl01kq	993	43	when	when	WRB
cord-010027-r0tl01kq	993	44	appropriate	appropriate	JJ
cord-010027-r0tl01kq	993	45	in	in	IN
cord-010027-r0tl01kq	993	46	a	a	DT
cord-010027-r0tl01kq	993	47	more	more	RBR
cord-010027-r0tl01kq	993	48	timely	timely	JJ
cord-010027-r0tl01kq	993	49	fashion	fashion	NN
cord-010027-r0tl01kq	993	50	.	.	.
cord-010027-r0tl01kq	994	1	Purpose	purpose	NN
cord-010027-r0tl01kq	994	2	of	of	IN
cord-010027-r0tl01kq	994	3	the	the	DT
cord-010027-r0tl01kq	994	4	Study	study	NN
cord-010027-r0tl01kq	994	5	:	:	:
cord-010027-r0tl01kq	994	6	This	this	DT
cord-010027-r0tl01kq	994	7	is	be	VBZ
cord-010027-r0tl01kq	994	8	a	a	DT
cord-010027-r0tl01kq	994	9	case	case	NN
cord-010027-r0tl01kq	994	10	report	report	NN
cord-010027-r0tl01kq	994	11	of	of	IN
cord-010027-r0tl01kq	994	12	a	a	DT
cord-010027-r0tl01kq	994	13	three	three	CD
cord-010027-r0tl01kq	994	14	year	year	NN
cord-010027-r0tl01kq	994	15	old	old	JJ
cord-010027-r0tl01kq	994	16	girl	girl	NN
cord-010027-r0tl01kq	994	17	who	who	WP
cord-010027-r0tl01kq	994	18	died	die	VBD
cord-010027-r0tl01kq	994	19	suddenly	suddenly	RB
cord-010027-r0tl01kq	994	20	at	at	IN
cord-010027-r0tl01kq	994	21	home	home	NN
cord-010027-r0tl01kq	994	22	.	.	.
cord-010027-r0tl01kq	995	1	An	an	DT
cord-010027-r0tl01kq	995	2	autopsy	autopsy	NN
cord-010027-r0tl01kq	995	3	was	be	VBD
cord-010027-r0tl01kq	995	4	performed	perform	VBN
cord-010027-r0tl01kq	995	5	in	in	IN
cord-010027-r0tl01kq	995	6	order	order	NN
cord-010027-r0tl01kq	995	7	to	to	TO
cord-010027-r0tl01kq	995	8	determine	determine	VB
cord-010027-r0tl01kq	995	9	the	the	DT
cord-010027-r0tl01kq	995	10	cause	cause	NN
cord-010027-r0tl01kq	995	11	of	of	IN
cord-010027-r0tl01kq	995	12	death	death	NN
cord-010027-r0tl01kq	995	13	.	.	.
cord-010027-r0tl01kq	996	1	Method	method	NN
cord-010027-r0tl01kq	996	2	:	:	:
cord-010027-r0tl01kq	997	1	An	an	DT
cord-010027-r0tl01kq	997	2	autopsy	autopsy	NN
cord-010027-r0tl01kq	997	3	was	be	VBD
cord-010027-r0tl01kq	997	4	conducted	conduct	VBN
cord-010027-r0tl01kq	997	5	which	which	WDT
cord-010027-r0tl01kq	997	6	showed	show	VBD
cord-010027-r0tl01kq	997	7	no	no	DT
cord-010027-r0tl01kq	997	8	gross	gross	JJ
cord-010027-r0tl01kq	997	9	abnormalities	abnormality	NNS
cord-010027-r0tl01kq	997	10	.	.	.
cord-010027-r0tl01kq	998	1	Microscopy	Microscopy	NNS
cord-010027-r0tl01kq	998	2	of	of	IN
cord-010027-r0tl01kq	998	3	the	the	DT
cord-010027-r0tl01kq	998	4	main	main	JJ
cord-010027-r0tl01kq	998	5	organs	organ	NNS
cord-010027-r0tl01kq	998	6	and	and	CC
cord-010027-r0tl01kq	998	7	microbiological	microbiological	JJ
cord-010027-r0tl01kq	998	8	samples	sample	NNS
cord-010027-r0tl01kq	998	9	were	be	VBD
cord-010027-r0tl01kq	998	10	taken	take	VBN
cord-010027-r0tl01kq	998	11	for	for	IN
cord-010027-r0tl01kq	998	12	further	further	JJ
cord-010027-r0tl01kq	998	13	assessment	assessment	NN
cord-010027-r0tl01kq	998	14	.	.	.
cord-010027-r0tl01kq	999	1	Results	result	NNS
cord-010027-r0tl01kq	999	2	:	:	:
cord-010027-r0tl01kq	1000	1	Histological	Histological	NNP
cord-010027-r0tl01kq	1000	2	assessment	assessment	NN
cord-010027-r0tl01kq	1000	3	of	of	IN
cord-010027-r0tl01kq	1000	4	the	the	DT
cord-010027-r0tl01kq	1000	5	heart	heart	NN
cord-010027-r0tl01kq	1000	6	showed	show	VBD
cord-010027-r0tl01kq	1000	7	multiple	multiple	JJ
cord-010027-r0tl01kq	1000	8	small	small	JJ
cord-010027-r0tl01kq	1000	9	foci	foci	NN
cord-010027-r0tl01kq	1000	10	of	of	IN
cord-010027-r0tl01kq	1000	11	lymphocytes	lymphocyte	NNS
cord-010027-r0tl01kq	1000	12	around	around	IN
cord-010027-r0tl01kq	1000	13	vessels	vessel	NNS
cord-010027-r0tl01kq	1000	14	and	and	CC
cord-010027-r0tl01kq	1000	15	within	within	IN
cord-010027-r0tl01kq	1000	16	the	the	DT
cord-010027-r0tl01kq	1000	17	interstitum	interstitum	NN
cord-010027-r0tl01kq	1000	18	of	of	IN
cord-010027-r0tl01kq	1000	19	the	the	DT
cord-010027-r0tl01kq	1000	20	epicardium	epicardium	NN
cord-010027-r0tl01kq	1000	21	,	,	,
cord-010027-r0tl01kq	1000	22	myocardium	myocardium	NN
cord-010027-r0tl01kq	1000	23	and	and	CC
cord-010027-r0tl01kq	1000	24	subendocardium	subendocardium	NN
cord-010027-r0tl01kq	1000	25	.	.	.
cord-010027-r0tl01kq	1001	1	These	these	DT
cord-010027-r0tl01kq	1001	2	lymphoid	lymphoid	JJ
cord-010027-r0tl01kq	1001	3	aggregates	aggregate	NNS
cord-010027-r0tl01kq	1001	4	consisted	consist	VBD
cord-010027-r0tl01kq	1001	5	of	of	IN
cord-010027-r0tl01kq	1001	6	20	20	CD
cord-010027-r0tl01kq	1001	7	-	-	SYM
cord-010027-r0tl01kq	1001	8	30	30	CD
cord-010027-r0tl01kq	1001	9	lymphocytes	lymphocyte	NNS
cord-010027-r0tl01kq	1001	10	up	up	IN
cord-010027-r0tl01kq	1001	11	to	to	IN
cord-010027-r0tl01kq	1001	12	larger	large	JJR
cord-010027-r0tl01kq	1001	13	numbers	number	NNS
cord-010027-r0tl01kq	1001	14	of	of	IN
cord-010027-r0tl01kq	1001	15	100	100	CD
cord-010027-r0tl01kq	1001	16	lymphocytes	lymphocyte	NNS
cord-010027-r0tl01kq	1001	17	collectively	collectively	RB
cord-010027-r0tl01kq	1001	18	.	.	.
cord-010027-r0tl01kq	1002	1	Several	several	JJ
cord-010027-r0tl01kq	1002	2	foci	focus	NNS
cord-010027-r0tl01kq	1002	3	were	be	VBD
cord-010027-r0tl01kq	1002	4	present	present	JJ
cord-010027-r0tl01kq	1002	5	within	within	IN
cord-010027-r0tl01kq	1002	6	virtually	virtually	RB
cord-010027-r0tl01kq	1002	7	all	all	DT
cord-010027-r0tl01kq	1002	8	of	of	IN
cord-010027-r0tl01kq	1002	9	the	the	DT
cord-010027-r0tl01kq	1002	10	sections	section	NNS
cord-010027-r0tl01kq	1002	11	taken	take	VBN
cord-010027-r0tl01kq	1002	12	in	in	IN
cord-010027-r0tl01kq	1002	13	both	both	CC
cord-010027-r0tl01kq	1002	14	right	right	NN
cord-010027-r0tl01kq	1002	15	and	and	CC
cord-010027-r0tl01kq	1002	16	left	left	JJ
cord-010027-r0tl01kq	1002	17	ventricles	ventricle	NNS
cord-010027-r0tl01kq	1002	18	.	.	.
cord-010027-r0tl01kq	1003	1	There	there	EX
cord-010027-r0tl01kq	1003	2	was	be	VBD
cord-010027-r0tl01kq	1003	3	no	no	DT
cord-010027-r0tl01kq	1003	4	evidence	evidence	NN
cord-010027-r0tl01kq	1003	5	of	of	IN
cord-010027-r0tl01kq	1003	6	myocyte	myocyte	NNP
cord-010027-r0tl01kq	1003	7	necrosis	necrosis	NN
cord-010027-r0tl01kq	1003	8	.	.	.
cord-010027-r0tl01kq	1004	1	Immunohistochemistry	Immunohistochemistry	NNP
cord-010027-r0tl01kq	1004	2	confirmed	confirm	VBD
cord-010027-r0tl01kq	1004	3	they	-PRON-	PRP
cord-010027-r0tl01kq	1004	4	were	be	VBD
cord-010027-r0tl01kq	1004	5	of	of	IN
cord-010027-r0tl01kq	1004	6	T	T	NNP
cord-010027-r0tl01kq	1004	7	lymphocyte	lymphocyte	NN
cord-010027-r0tl01kq	1004	8	cell	cell	NN
cord-010027-r0tl01kq	1004	9	origin	origin	NN
cord-010027-r0tl01kq	1004	10	admixed	admix	VBN
cord-010027-r0tl01kq	1004	11	with	with	IN
cord-010027-r0tl01kq	1004	12	smaller	small	JJR
cord-010027-r0tl01kq	1004	13	numbers	number	NNS
cord-010027-r0tl01kq	1004	14	of	of	IN
cord-010027-r0tl01kq	1004	15	macrophages	macrophage	NNS
cord-010027-r0tl01kq	1004	16	.	.	.
cord-010027-r0tl01kq	1005	1	Histology	histology	NN
cord-010027-r0tl01kq	1005	2	from	from	IN
cord-010027-r0tl01kq	1005	3	the	the	DT
cord-010027-r0tl01kq	1005	4	respiratory	respiratory	JJ
cord-010027-r0tl01kq	1005	5	system	system	NN
cord-010027-r0tl01kq	1005	6	showed	show	VBD
cord-010027-r0tl01kq	1005	7	a	a	DT
cord-010027-r0tl01kq	1005	8	diffuse	diffuse	JJ
cord-010027-r0tl01kq	1005	9	subepithelial	subepithelial	JJ
cord-010027-r0tl01kq	1005	10	lymphocytic	lymphocytic	JJ
cord-010027-r0tl01kq	1005	11	infiltrate	infiltrate	NN
cord-010027-r0tl01kq	1005	12	in	in	IN
cord-010027-r0tl01kq	1005	13	the	the	DT
cord-010027-r0tl01kq	1005	14	larynx	larynx	NN
cord-010027-r0tl01kq	1005	15	and	and	CC
cord-010027-r0tl01kq	1005	16	trachea	trachea	NN
cord-010027-r0tl01kq	1005	17	,	,	,
cord-010027-r0tl01kq	1005	18	and	and	CC
cord-010027-r0tl01kq	1005	19	the	the	DT
cord-010027-r0tl01kq	1005	20	nasopharyngeal	nasopharyngeal	JJ
cord-010027-r0tl01kq	1005	21	samples	sample	NNS
cord-010027-r0tl01kq	1005	22	detected	detect	VBD
cord-010027-r0tl01kq	1005	23	Coronavirus	Coronavirus	NNP
cord-010027-r0tl01kq	1005	24	,	,	,
cord-010027-r0tl01kq	1005	25	Adenovirus	Adenovirus	NNP
cord-010027-r0tl01kq	1005	26	and	and	CC
cord-010027-r0tl01kq	1005	27	two	two	CD
cord-010027-r0tl01kq	1005	28	types	type	NNS
cord-010027-r0tl01kq	1005	29	of	of	IN
cord-010027-r0tl01kq	1005	30	Parainfluenza	Parainfluenza	NNP
cord-010027-r0tl01kq	1005	31	virus	virus	NN
cord-010027-r0tl01kq	1005	32	.	.	.
cord-010027-r0tl01kq	1006	1	However	however	RB
cord-010027-r0tl01kq	1006	2	,	,	,
cord-010027-r0tl01kq	1006	3	viral	viral	JJ
cord-010027-r0tl01kq	1006	4	polymerase	polymerase	NN
cord-010027-r0tl01kq	1006	5	chain	chain	NN
cord-010027-r0tl01kq	1006	6	reaction	reaction	NN
cord-010027-r0tl01kq	1006	7	(	(	-LRB-
cord-010027-r0tl01kq	1006	8	PCR	PCR	NNP
cord-010027-r0tl01kq	1006	9	)	)	-RRB-
cord-010027-r0tl01kq	1006	10	from	from	IN
cord-010027-r0tl01kq	1006	11	the	the	DT
cord-010027-r0tl01kq	1006	12	cardiac	cardiac	JJ
cord-010027-r0tl01kq	1006	13	tissue	tissue	NN
cord-010027-r0tl01kq	1006	14	was	be	VBD
cord-010027-r0tl01kq	1006	15	negative	negative	JJ
cord-010027-r0tl01kq	1006	16	.	.	.
cord-010027-r0tl01kq	1007	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1007	2	:	:	:
cord-010027-r0tl01kq	1008	1	An	an	DT
cord-010027-r0tl01kq	1008	2	unequivocal	unequivocal	JJ
cord-010027-r0tl01kq	1008	3	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1008	4	of	of	IN
cord-010027-r0tl01kq	1008	5	a	a	DT
cord-010027-r0tl01kq	1008	6	myocarditis	myocarditis	NN
cord-010027-r0tl01kq	1008	7	could	could	MD
cord-010027-r0tl01kq	1008	8	not	not	RB
cord-010027-r0tl01kq	1008	9	be	be	VB
cord-010027-r0tl01kq	1008	10	made	make	VBN
cord-010027-r0tl01kq	1008	11	in	in	IN
cord-010027-r0tl01kq	1008	12	this	this	DT
cord-010027-r0tl01kq	1008	13	case	case	NN
cord-010027-r0tl01kq	1008	14	due	due	IN
cord-010027-r0tl01kq	1008	15	to	to	IN
cord-010027-r0tl01kq	1008	16	the	the	DT
cord-010027-r0tl01kq	1008	17	lack	lack	NN
cord-010027-r0tl01kq	1008	18	of	of	IN
cord-010027-r0tl01kq	1008	19	myocyte	myocyte	NNP
cord-010027-r0tl01kq	1008	20	necrosis	necrosis	NN
cord-010027-r0tl01kq	1008	21	and	and	CC
cord-010027-r0tl01kq	1008	22	the	the	DT
cord-010027-r0tl01kq	1008	23	absence	absence	NN
cord-010027-r0tl01kq	1008	24	of	of	IN
cord-010027-r0tl01kq	1008	25	viral	viral	JJ
cord-010027-r0tl01kq	1008	26	DNA	dna	NN
cord-010027-r0tl01kq	1008	27	within	within	IN
cord-010027-r0tl01kq	1008	28	the	the	DT
cord-010027-r0tl01kq	1008	29	cardiac	cardiac	JJ
cord-010027-r0tl01kq	1008	30	tissue	tissue	NN
cord-010027-r0tl01kq	1008	31	.	.	.
cord-010027-r0tl01kq	1009	1	Genetic	genetic	JJ
cord-010027-r0tl01kq	1009	2	testing	testing	NN
cord-010027-r0tl01kq	1009	3	was	be	VBD
cord-010027-r0tl01kq	1009	4	strongly	strongly	RB
cord-010027-r0tl01kq	1009	5	advised	advise	VBN
cord-010027-r0tl01kq	1009	6	as	as	IN
cord-010027-r0tl01kq	1009	7	splenic	splenic	JJ
cord-010027-r0tl01kq	1009	8	material	material	NN
cord-010027-r0tl01kq	1009	9	had	have	VBD
cord-010027-r0tl01kq	1009	10	been	be	VBN
cord-010027-r0tl01kq	1009	11	taken	take	VBN
cord-010027-r0tl01kq	1009	12	at	at	IN
cord-010027-r0tl01kq	1009	13	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1009	14	and	and	CC
cord-010027-r0tl01kq	1009	15	following	follow	VBG
cord-010027-r0tl01kq	1009	16	molecular	molecular	JJ
cord-010027-r0tl01kq	1009	17	genetic	genetic	JJ
cord-010027-r0tl01kq	1009	18	techniques	technique	NNS
cord-010027-r0tl01kq	1009	19	a	a	DT
cord-010027-r0tl01kq	1009	20	mutation	mutation	NN
cord-010027-r0tl01kq	1009	21	was	be	VBD
cord-010027-r0tl01kq	1009	22	detected	detect	VBN
cord-010027-r0tl01kq	1009	23	in	in	IN
cord-010027-r0tl01kq	1009	24	the	the	DT
cord-010027-r0tl01kq	1009	25	sodium	sodium	NN
cord-010027-r0tl01kq	1009	26	channel	channel	NN
cord-010027-r0tl01kq	1009	27	indicating	indicate	VBG
cord-010027-r0tl01kq	1009	28	an	an	DT
cord-010027-r0tl01kq	1009	29	inherited	inherit	VBN
cord-010027-r0tl01kq	1009	30	ion	ion	NN
cord-010027-r0tl01kq	1009	31	channelopathy	channelopathy	NN
cord-010027-r0tl01kq	1009	32	.	.	.
cord-010027-r0tl01kq	1010	1	Further	further	JJ
cord-010027-r0tl01kq	1010	2	genetic	genetic	JJ
cord-010027-r0tl01kq	1010	3	counselling	counselling	NN
cord-010027-r0tl01kq	1010	4	and	and	CC
cord-010027-r0tl01kq	1010	5	testing	testing	NN
cord-010027-r0tl01kq	1010	6	of	of	IN
cord-010027-r0tl01kq	1010	7	the	the	DT
cord-010027-r0tl01kq	1010	8	remaining	remain	VBG
cord-010027-r0tl01kq	1010	9	siblings	sibling	NNS
cord-010027-r0tl01kq	1010	10	and	and	CC
cord-010027-r0tl01kq	1010	11	family	family	NN
cord-010027-r0tl01kq	1010	12	members	member	NNS
cord-010027-r0tl01kq	1010	13	is	be	VBZ
cord-010027-r0tl01kq	1010	14	being	be	VBG
cord-010027-r0tl01kq	1010	15	performed	perform	VBN
cord-010027-r0tl01kq	1010	16	.	.	.
cord-010027-r0tl01kq	1011	1	Varicose	varicose	JJ
cord-010027-r0tl01kq	1011	2	veins	vein	NNS
cord-010027-r0tl01kq	1011	3	affect	affect	VBP
cord-010027-r0tl01kq	1011	4	a	a	DT
cord-010027-r0tl01kq	1011	5	third	third	NN
cord-010027-r0tl01kq	1011	6	of	of	IN
cord-010027-r0tl01kq	1011	7	the	the	DT
cord-010027-r0tl01kq	1011	8	UK	UK	NNP
cord-010027-r0tl01kq	1011	9	population	population	NN
cord-010027-r0tl01kq	1011	10	.	.	.
cord-010027-r0tl01kq	1012	1	Isolated	isolate	VBN
cord-010027-r0tl01kq	1012	2	case	case	NN
cord-010027-r0tl01kq	1012	3	reports	report	NNS
cord-010027-r0tl01kq	1012	4	and	and	CC
cord-010027-r0tl01kq	1012	5	small	small	JJ
cord-010027-r0tl01kq	1012	6	series	series	NN
cord-010027-r0tl01kq	1012	7	of	of	IN
cord-010027-r0tl01kq	1012	8	fatalities	fatality	NNS
cord-010027-r0tl01kq	1012	9	resulting	result	VBG
cord-010027-r0tl01kq	1012	10	from	from	IN
cord-010027-r0tl01kq	1012	11	varicose	varicose	JJ
cord-010027-r0tl01kq	1012	12	vein	vein	NN
cord-010027-r0tl01kq	1012	13	haemorrhage	haemorrhage	NN
cord-010027-r0tl01kq	1012	14	appear	appear	VBP
cord-010027-r0tl01kq	1012	15	in	in	IN
cord-010027-r0tl01kq	1012	16	the	the	DT
cord-010027-r0tl01kq	1012	17	literature	literature	NN
cord-010027-r0tl01kq	1012	18	infrequently	infrequently	RB
cord-010027-r0tl01kq	1012	19	.	.	.
cord-010027-r0tl01kq	1013	1	Some	some	DT
cord-010027-r0tl01kq	1013	2	of	of	IN
cord-010027-r0tl01kq	1013	3	the	the	DT
cord-010027-r0tl01kq	1013	4	earliest	early	JJS
cord-010027-r0tl01kq	1013	5	reports	report	NNS
cord-010027-r0tl01kq	1013	6	of	of	IN
cord-010027-r0tl01kq	1013	7	fatality	fatality	NN
cord-010027-r0tl01kq	1013	8	we	-PRON-	PRP
cord-010027-r0tl01kq	1013	9	have	have	VBP
cord-010027-r0tl01kq	1013	10	found	find	VBN
cord-010027-r0tl01kq	1013	11	appear	appear	VBP
cord-010027-r0tl01kq	1013	12	in	in	IN
cord-010027-r0tl01kq	1013	13	British	British	NNP
cord-010027-r0tl01kq	1013	14	Medical	Medical	NNP
cord-010027-r0tl01kq	1013	15	Journal	Journal	NNP
cord-010027-r0tl01kq	1013	16	(	(	-LRB-
cord-010027-r0tl01kq	1013	17	1958	1958	CD
cord-010027-r0tl01kq	1013	18	)	)	-RRB-
cord-010027-r0tl01kq	1013	19	and	and	CC
cord-010027-r0tl01kq	1013	20	the	the	DT
cord-010027-r0tl01kq	1013	21	Lancet	Lancet	NNP
cord-010027-r0tl01kq	1013	22	(	(	-LRB-
cord-010027-r0tl01kq	1013	23	1973	1973	CD
cord-010027-r0tl01kq	1013	24	)	)	-RRB-
cord-010027-r0tl01kq	1013	25	,	,	,
cord-010027-r0tl01kq	1013	26	more	more	RBR
cord-010027-r0tl01kq	1013	27	recently	recently	RB
cord-010027-r0tl01kq	1013	28	they	-PRON-	PRP
cord-010027-r0tl01kq	1013	29	have	have	VBP
cord-010027-r0tl01kq	1013	30	appeared	appear	VBN
cord-010027-r0tl01kq	1013	31	in	in	IN
cord-010027-r0tl01kq	1013	32	journals	journal	NNS
cord-010027-r0tl01kq	1013	33	of	of	IN
cord-010027-r0tl01kq	1013	34	forensic	forensic	JJ
cord-010027-r0tl01kq	1013	35	pathology	pathology	NN
cord-010027-r0tl01kq	1013	36	.	.	.
cord-010027-r0tl01kq	1014	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1014	2	purpose	purpose	NN
cord-010027-r0tl01kq	1014	3	is	be	VBZ
cord-010027-r0tl01kq	1014	4	to	to	TO
cord-010027-r0tl01kq	1014	5	establish	establish	VB
cord-010027-r0tl01kq	1014	6	and	and	CC
cord-010027-r0tl01kq	1014	7	bring	bring	VB
cord-010027-r0tl01kq	1014	8	attention	attention	NN
cord-010027-r0tl01kq	1014	9	to	to	IN
cord-010027-r0tl01kq	1014	10	the	the	DT
cord-010027-r0tl01kq	1014	11	rarity	rarity	NN
cord-010027-r0tl01kq	1014	12	of	of	IN
cord-010027-r0tl01kq	1014	13	fatality	fatality	NN
cord-010027-r0tl01kq	1014	14	resulting	result	VBG
cord-010027-r0tl01kq	1014	15	from	from	IN
cord-010027-r0tl01kq	1014	16	varicose	varicose	JJ
cord-010027-r0tl01kq	1014	17	vein	vein	NN
cord-010027-r0tl01kq	1014	18	haemorrhage	haemorrhage	NN
cord-010027-r0tl01kq	1014	19	and	and	CC
cord-010027-r0tl01kq	1014	20	the	the	DT
cord-010027-r0tl01kq	1014	21	importance	importance	NN
cord-010027-r0tl01kq	1014	22	of	of	IN
cord-010027-r0tl01kq	1014	23	the	the	DT
cord-010027-r0tl01kq	1014	24	scene	scene	NN
cord-010027-r0tl01kq	1014	25	of	of	IN
cord-010027-r0tl01kq	1014	26	death	death	NN
cord-010027-r0tl01kq	1014	27	and	and	CC
cord-010027-r0tl01kq	1014	28	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1014	29	findings	finding	NNS
cord-010027-r0tl01kq	1014	30	.	.	.
cord-010027-r0tl01kq	1015	1	A	a	DT
cord-010027-r0tl01kq	1015	2	literature	literature	NN
cord-010027-r0tl01kq	1015	3	review	review	NN
cord-010027-r0tl01kq	1015	4	was	be	VBD
cord-010027-r0tl01kq	1015	5	undertaken	undertake	VBN
cord-010027-r0tl01kq	1015	6	,	,	,
cord-010027-r0tl01kq	1015	7	we	-PRON-	PRP
cord-010027-r0tl01kq	1015	8	obtained	obtain	VBD
cord-010027-r0tl01kq	1015	9	relevant	relevant	JJ
cord-010027-r0tl01kq	1015	10	Office	Office	NNP
cord-010027-r0tl01kq	1015	11	of	of	IN
cord-010027-r0tl01kq	1015	12	National	National	NNP
cord-010027-r0tl01kq	1015	13	Statistics	Statistics	NNPS
cord-010027-r0tl01kq	1015	14	(	(	-LRB-
cord-010027-r0tl01kq	1015	15	ONS	ONS	NNP
cord-010027-r0tl01kq	1015	16	)	)	-RRB-
cord-010027-r0tl01kq	1015	17	mortality	mortality	NN
cord-010027-r0tl01kq	1015	18	data	datum	NNS
cord-010027-r0tl01kq	1015	19	for	for	IN
cord-010027-r0tl01kq	1015	20	the	the	DT
cord-010027-r0tl01kq	1015	21	years	year	NNS
cord-010027-r0tl01kq	1015	22	2011	2011	CD
cord-010027-r0tl01kq	1015	23	-	-	SYM
cord-010027-r0tl01kq	1015	24	2013	2013	CD
cord-010027-r0tl01kq	1015	25	,	,	,
cord-010027-r0tl01kq	1015	26	and	and	CC
cord-010027-r0tl01kq	1015	27	reviewed	review	VBD
cord-010027-r0tl01kq	1015	28	our	-PRON-	PRP$
cord-010027-r0tl01kq	1015	29	own	own	JJ
cord-010027-r0tl01kq	1015	30	post	post	JJ
cord-010027-r0tl01kq	1015	31	-	-	JJ
cord-010027-r0tl01kq	1015	32	mortem	mortem	JJ
cord-010027-r0tl01kq	1015	33	records	record	NNS
cord-010027-r0tl01kq	1015	34	for	for	IN
cord-010027-r0tl01kq	1015	35	demographic	demographic	JJ
cord-010027-r0tl01kq	1015	36	,	,	,
cord-010027-r0tl01kq	1015	37	clinical	clinical	JJ
cord-010027-r0tl01kq	1015	38	and	and	CC
cord-010027-r0tl01kq	1015	39	scene	scene	NN
cord-010027-r0tl01kq	1015	40	of	of	IN
cord-010027-r0tl01kq	1015	41	death	death	NN
cord-010027-r0tl01kq	1015	42	information	information	NN
cord-010027-r0tl01kq	1015	43	in	in	IN
cord-010027-r0tl01kq	1015	44	cases	case	NNS
cord-010027-r0tl01kq	1015	45	we	-PRON-	PRP
cord-010027-r0tl01kq	1015	46	have	have	VBP
cord-010027-r0tl01kq	1015	47	encountered	encounter	VBN
cord-010027-r0tl01kq	1015	48	.	.	.
cord-010027-r0tl01kq	1016	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1016	2	findings	finding	NNS
cord-010027-r0tl01kq	1016	3	confirm	confirm	VBP
cord-010027-r0tl01kq	1016	4	that	that	IN
cord-010027-r0tl01kq	1016	5	fatality	fatality	NN
cord-010027-r0tl01kq	1016	6	resulting	result	VBG
cord-010027-r0tl01kq	1016	7	from	from	IN
cord-010027-r0tl01kq	1016	8	varicose	varicose	JJ
cord-010027-r0tl01kq	1016	9	veins	vein	NNS
cord-010027-r0tl01kq	1016	10	remains	remain	VBZ
cord-010027-r0tl01kq	1016	11	a	a	DT
cord-010027-r0tl01kq	1016	12	rare	rare	JJ
cord-010027-r0tl01kq	1016	13	cause	cause	NN
cord-010027-r0tl01kq	1016	14	of	of	IN
cord-010027-r0tl01kq	1016	15	death	death	NN
cord-010027-r0tl01kq	1016	16	.	.	.
cord-010027-r0tl01kq	1017	1	Some	some	DT
cord-010027-r0tl01kq	1017	2	of	of	IN
cord-010027-r0tl01kq	1017	3	these	these	DT
cord-010027-r0tl01kq	1017	4	deaths	death	NNS
cord-010027-r0tl01kq	1017	5	are	be	VBP
cord-010027-r0tl01kq	1017	6	preventable	preventable	JJ
cord-010027-r0tl01kq	1017	7	and	and	CC
cord-010027-r0tl01kq	1017	8	in	in	IN
cord-010027-r0tl01kq	1017	9	2013	2013	CD
cord-010027-r0tl01kq	1017	10	NICE	nice	JJ
cord-010027-r0tl01kq	1017	11	(	(	-LRB-
cord-010027-r0tl01kq	1017	12	National	National	NNP
cord-010027-r0tl01kq	1017	13	Institute	Institute	NNP
cord-010027-r0tl01kq	1017	14	of	of	IN
cord-010027-r0tl01kq	1017	15	Health	Health	NNP
cord-010027-r0tl01kq	1017	16	and	and	CC
cord-010027-r0tl01kq	1017	17	Care	Care	NNP
cord-010027-r0tl01kq	1017	18	Excellence	Excellence	NNP
cord-010027-r0tl01kq	1017	19	,	,	,
cord-010027-r0tl01kq	1017	20	UK	UK	NNP
cord-010027-r0tl01kq	1017	21	)	)	-RRB-
cord-010027-r0tl01kq	1017	22	issued	issue	VBD
cord-010027-r0tl01kq	1017	23	guidelines	guideline	NNS
cord-010027-r0tl01kq	1017	24	in	in	IN
cord-010027-r0tl01kq	1017	25	which	which	WDT
cord-010027-r0tl01kq	1017	26	haemorrhage	haemorrhage	NN
cord-010027-r0tl01kq	1017	27	from	from	IN
cord-010027-r0tl01kq	1017	28	varicose	varicose	JJ
cord-010027-r0tl01kq	1017	29	veins	vein	NNS
cord-010027-r0tl01kq	1017	30	constitute	constitute	VBP
cord-010027-r0tl01kq	1017	31	a	a	DT
cord-010027-r0tl01kq	1017	32	vascular	vascular	JJ
cord-010027-r0tl01kq	1017	33	emergency	emergency	NN
cord-010027-r0tl01kq	1017	34	.	.	.
cord-010027-r0tl01kq	1018	1	Importantly	importantly	RB
cord-010027-r0tl01kq	1018	2	emphasis	emphasis	NN
cord-010027-r0tl01kq	1018	3	on	on	IN
cord-010027-r0tl01kq	1018	4	first	first	JJ
cord-010027-r0tl01kq	1018	5	aid	aid	NN
cord-010027-r0tl01kq	1018	6	is	be	VBZ
cord-010027-r0tl01kq	1018	7	required	require	VBN
cord-010027-r0tl01kq	1018	8	,	,	,
cord-010027-r0tl01kq	1018	9	simply	simply	RB
cord-010027-r0tl01kq	1018	10	elevating	elevate	VBG
cord-010027-r0tl01kq	1018	11	the	the	DT
cord-010027-r0tl01kq	1018	12	limb	limb	NN
cord-010027-r0tl01kq	1018	13	stops	stop	VBZ
cord-010027-r0tl01kq	1018	14	bleeding	bleed	VBG
cord-010027-r0tl01kq	1018	15	and	and	CC
cord-010027-r0tl01kq	1018	16	is	be	VBZ
cord-010027-r0tl01kq	1018	17	life	life	NN
cord-010027-r0tl01kq	1018	18	saving	saving	NN
cord-010027-r0tl01kq	1018	19	,	,	,
cord-010027-r0tl01kq	1018	20	whereas	whereas	IN
cord-010027-r0tl01kq	1018	21	direct	direct	JJ
cord-010027-r0tl01kq	1018	22	pressure	pressure	NN
cord-010027-r0tl01kq	1018	23	and	and	CC
cord-010027-r0tl01kq	1018	24	tourniquets	tourniquet	NNS
cord-010027-r0tl01kq	1018	25	do	do	VBP
cord-010027-r0tl01kq	1018	26	not	not	RB
cord-010027-r0tl01kq	1018	27	.	.	.
cord-010027-r0tl01kq	1019	1	Pathologists	pathologist	NNS
cord-010027-r0tl01kq	1019	2	should	should	MD
cord-010027-r0tl01kq	1019	3	be	be	VB
cord-010027-r0tl01kq	1019	4	aware	aware	JJ
cord-010027-r0tl01kq	1019	5	of	of	IN
cord-010027-r0tl01kq	1019	6	potential	potential	JJ
cord-010027-r0tl01kq	1019	7	findings	finding	NNS
cord-010027-r0tl01kq	1019	8	at	at	IN
cord-010027-r0tl01kq	1019	9	autopsy	autopsy	NN
cord-010027-r0tl01kq	1019	10	in	in	IN
cord-010027-r0tl01kq	1019	11	these	these	DT
cord-010027-r0tl01kq	1019	12	cases	case	NNS
cord-010027-r0tl01kq	1019	13	.	.	.
cord-010027-r0tl01kq	1020	1	In	in	IN
cord-010027-r0tl01kq	1020	2	particular	particular	JJ
cord-010027-r0tl01kq	1020	3	,	,	,
cord-010027-r0tl01kq	1020	4	awareness	awareness	NN
cord-010027-r0tl01kq	1020	5	that	that	IN
cord-010027-r0tl01kq	1020	6	even	even	RB
cord-010027-r0tl01kq	1020	7	obscure	obscure	JJ
cord-010027-r0tl01kq	1020	8	minor	minor	JJ
cord-010027-r0tl01kq	1020	9	injury	injury	NN
cord-010027-r0tl01kq	1020	10	to	to	IN
cord-010027-r0tl01kq	1020	11	a	a	DT
cord-010027-r0tl01kq	1020	12	varicose	varicose	JJ
cord-010027-r0tl01kq	1020	13	vein	vein	NN
cord-010027-r0tl01kq	1020	14	could	could	MD
cord-010027-r0tl01kq	1020	15	have	have	VB
cord-010027-r0tl01kq	1020	16	resulted	result	VBN
cord-010027-r0tl01kq	1020	17	in	in	IN
cord-010027-r0tl01kq	1020	18	significant	significant	JJ
cord-010027-r0tl01kq	1020	19	blood	blood	NN
cord-010027-r0tl01kq	1020	20	loss	loss	NN
cord-010027-r0tl01kq	1020	21	leading	lead	VBG
cord-010027-r0tl01kq	1020	22	to	to	IN
cord-010027-r0tl01kq	1020	23	death	death	NN
cord-010027-r0tl01kq	1020	24	.	.	.
cord-010027-r0tl01kq	1021	1	Blood	blood	NN
cord-010027-r0tl01kq	1021	2	lost	lose	VBN
cord-010027-r0tl01kq	1021	3	at	at	IN
cord-010027-r0tl01kq	1021	4	the	the	DT
cord-010027-r0tl01kq	1021	5	scene	scene	NN
cord-010027-r0tl01kq	1021	6	will	will	MD
cord-010027-r0tl01kq	1021	7	not	not	RB
cord-010027-r0tl01kq	1021	8	be	be	VB
cord-010027-r0tl01kq	1021	9	apparent	apparent	JJ
cord-010027-r0tl01kq	1021	10	at	at	IN
cord-010027-r0tl01kq	1021	11	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1021	12	,	,	,
cord-010027-r0tl01kq	1021	13	and	and	CC
cord-010027-r0tl01kq	1021	14	details	detail	NNS
cord-010027-r0tl01kq	1021	15	of	of	IN
cord-010027-r0tl01kq	1021	16	blood	blood	NN
cord-010027-r0tl01kq	1021	17	loss	loss	NN
cord-010027-r0tl01kq	1021	18	could	could	MD
cord-010027-r0tl01kq	1021	19	be	be	VB
cord-010027-r0tl01kq	1021	20	variably	variably	RB
cord-010027-r0tl01kq	1021	21	recorded	record	VBN
cord-010027-r0tl01kq	1021	22	on	on	IN
cord-010027-r0tl01kq	1021	23	the	the	DT
cord-010027-r0tl01kq	1021	24	scene	scene	NN
cord-010027-r0tl01kq	1021	25	of	of	IN
cord-010027-r0tl01kq	1021	26	death	death	NN
cord-010027-r0tl01kq	1021	27	information	information	NN
cord-010027-r0tl01kq	1021	28	provided	provide	VBN
cord-010027-r0tl01kq	1021	29	,	,	,
cord-010027-r0tl01kq	1021	30	therefore	therefore	RB
cord-010027-r0tl01kq	1021	31	vigilance	vigilance	NN
cord-010027-r0tl01kq	1021	32	is	be	VBZ
cord-010027-r0tl01kq	1021	33	required	require	VBN
cord-010027-r0tl01kq	1021	34	.	.	.
cord-010027-r0tl01kq	1022	1	Histopathologists	histopathologist	NNS
cord-010027-r0tl01kq	1022	2	practice	practice	VBP
cord-010027-r0tl01kq	1022	3	in	in	IN
cord-010027-r0tl01kq	1022	4	an	an	DT
cord-010027-r0tl01kq	1022	5	era	era	NN
cord-010027-r0tl01kq	1022	6	of	of	IN
cord-010027-r0tl01kq	1022	7	ever	ever	RB
cord-010027-r0tl01kq	1022	8	advancing	advance	VBG
cord-010027-r0tl01kq	1022	9	medical	medical	JJ
cord-010027-r0tl01kq	1022	10	treatments	treatment	NNS
cord-010027-r0tl01kq	1022	11	for	for	IN
cord-010027-r0tl01kq	1022	12	a	a	DT
cord-010027-r0tl01kq	1022	13	wide	wide	JJ
cord-010027-r0tl01kq	1022	14	variety	variety	NN
cord-010027-r0tl01kq	1022	15	of	of	IN
cord-010027-r0tl01kq	1022	16	oncological	oncological	JJ
cord-010027-r0tl01kq	1022	17	,	,	,
cord-010027-r0tl01kq	1022	18	neurological	neurological	JJ
cord-010027-r0tl01kq	1022	19	,	,	,
cord-010027-r0tl01kq	1022	20	haematological	haematological	JJ
cord-010027-r0tl01kq	1022	21	and	and	CC
cord-010027-r0tl01kq	1022	22	rheumatological	rheumatological	JJ
cord-010027-r0tl01kq	1022	23	diseases	disease	NNS
cord-010027-r0tl01kq	1022	24	.	.	.
cord-010027-r0tl01kq	1023	1	Immune	immune	JJ
cord-010027-r0tl01kq	1023	2	modulating	modulate	VBG
cord-010027-r0tl01kq	1023	3	therapies	therapy	NNS
cord-010027-r0tl01kq	1023	4	are	be	VBP
cord-010027-r0tl01kq	1023	5	taking	take	VBG
cord-010027-r0tl01kq	1023	6	a	a	DT
cord-010027-r0tl01kq	1023	7	more	more	RBR
cord-010027-r0tl01kq	1023	8	prominent	prominent	JJ
cord-010027-r0tl01kq	1023	9	place	place	NN
cord-010027-r0tl01kq	1023	10	in	in	IN
cord-010027-r0tl01kq	1023	11	clinical	clinical	JJ
cord-010027-r0tl01kq	1023	12	practice	practice	NN
cord-010027-r0tl01kq	1023	13	.	.	.
cord-010027-r0tl01kq	1024	1	However	however	RB
cord-010027-r0tl01kq	1024	2	,	,	,
cord-010027-r0tl01kq	1024	3	with	with	IN
cord-010027-r0tl01kq	1024	4	such	such	JJ
cord-010027-r0tl01kq	1024	5	great	great	JJ
cord-010027-r0tl01kq	1024	6	advances	advance	NNS
cord-010027-r0tl01kq	1024	7	in	in	IN
cord-010027-r0tl01kq	1024	8	therapy	therapy	NN
cord-010027-r0tl01kq	1024	9	comes	come	VBZ
cord-010027-r0tl01kq	1024	10	great	great	JJ
cord-010027-r0tl01kq	1024	11	risk	risk	NN
cord-010027-r0tl01kq	1024	12	,	,	,
cord-010027-r0tl01kq	1024	13	with	with	IN
cord-010027-r0tl01kq	1024	14	the	the	DT
cord-010027-r0tl01kq	1024	15	potential	potential	NN
cord-010027-r0tl01kq	1024	16	of	of	IN
cord-010027-r0tl01kq	1024	17	life	life	NN
cord-010027-r0tl01kq	1024	18	threatening	threaten	VBG
cord-010027-r0tl01kq	1024	19	opportunistic	opportunistic	JJ
cord-010027-r0tl01kq	1024	20	infections	infection	NNS
cord-010027-r0tl01kq	1024	21	in	in	IN
cord-010027-r0tl01kq	1024	22	our	-PRON-	PRP$
cord-010027-r0tl01kq	1024	23	patients	patient	NNS
cord-010027-r0tl01kq	1024	24	.	.	.
cord-010027-r0tl01kq	1025	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1025	2	present	present	VBP
cord-010027-r0tl01kq	1025	3	a	a	DT
cord-010027-r0tl01kq	1025	4	series	series	NN
cord-010027-r0tl01kq	1025	5	of	of	IN
cord-010027-r0tl01kq	1025	6	9	9	CD
cord-010027-r0tl01kq	1025	7	immunosuppressed	immunosuppressed	JJ
cord-010027-r0tl01kq	1025	8	patients	patient	NNS
cord-010027-r0tl01kq	1025	9	who	who	WP
cord-010027-r0tl01kq	1025	10	acquired	acquire	VBD
cord-010027-r0tl01kq	1025	11	such	such	JJ
cord-010027-r0tl01kq	1025	12	infections	infection	NNS
cord-010027-r0tl01kq	1025	13	and	and	CC
cord-010027-r0tl01kq	1025	14	in	in	IN
cord-010027-r0tl01kq	1025	15	whom	whom	WP
cord-010027-r0tl01kq	1025	16	the	the	DT
cord-010027-r0tl01kq	1025	17	diagnoses	diagnosis	NNS
cord-010027-r0tl01kq	1025	18	were	be	VBD
cord-010027-r0tl01kq	1025	19	made	make	VBN
cord-010027-r0tl01kq	1025	20	by	by	IN
cord-010027-r0tl01kq	1025	21	histopathological	histopathological	JJ
cord-010027-r0tl01kq	1025	22	examination	examination	NN
cord-010027-r0tl01kq	1025	23	.	.	.
cord-010027-r0tl01kq	1026	1	The	the	DT
cord-010027-r0tl01kq	1026	2	spectrum	spectrum	NN
cord-010027-r0tl01kq	1026	3	of	of	IN
cord-010027-r0tl01kq	1026	4	these	these	DT
cord-010027-r0tl01kq	1026	5	pathogens	pathogen	NNS
cord-010027-r0tl01kq	1026	6	ranges	range	VBZ
cord-010027-r0tl01kq	1026	7	from	from	IN
cord-010027-r0tl01kq	1026	8	viral	viral	JJ
cord-010027-r0tl01kq	1026	9	(	(	-LRB-
cord-010027-r0tl01kq	1026	10	CMV	CMV	NNP
cord-010027-r0tl01kq	1026	11	,	,	,
cord-010027-r0tl01kq	1026	12	EBV	EBV	NNP
cord-010027-r0tl01kq	1026	13	,	,	,
cord-010027-r0tl01kq	1026	14	Herpes	Herpes	NNP
cord-010027-r0tl01kq	1026	15	)	)	-RRB-
cord-010027-r0tl01kq	1026	16	,	,	,
cord-010027-r0tl01kq	1026	17	parasitic	parasitic	JJ
cord-010027-r0tl01kq	1026	18	(	(	-LRB-
cord-010027-r0tl01kq	1026	19	strongyloides	strongyloide	NNS
cord-010027-r0tl01kq	1026	20	)	)	-RRB-
cord-010027-r0tl01kq	1026	21	to	to	TO
cord-010027-r0tl01kq	1026	22	fungal	fungal	VB
cord-010027-r0tl01kq	1026	23	(	(	-LRB-
cord-010027-r0tl01kq	1026	24	P.	P.	NNP
cord-010027-r0tl01kq	1026	25	jirovecii	jirovecii	NNP
cord-010027-r0tl01kq	1026	26	,	,	,
cord-010027-r0tl01kq	1026	27	cryptococcus	cryptococcus	NNP
cord-010027-r0tl01kq	1026	28	)	)	-RRB-
cord-010027-r0tl01kq	1026	29	,	,	,
cord-010027-r0tl01kq	1026	30	and	and	CC
cord-010027-r0tl01kq	1026	31	the	the	DT
cord-010027-r0tl01kq	1026	32	range	range	NN
cord-010027-r0tl01kq	1026	33	of	of	IN
cord-010027-r0tl01kq	1026	34	infections	infection	NNS
cord-010027-r0tl01kq	1026	35	is	be	VBZ
cord-010027-r0tl01kq	1026	36	diverse	diverse	JJ
cord-010027-r0tl01kq	1026	37	.	.	.
cord-010027-r0tl01kq	1027	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1027	2	series	series	NN
cord-010027-r0tl01kq	1027	3	includes	include	VBZ
cord-010027-r0tl01kq	1027	4	4	4	CD
cord-010027-r0tl01kq	1027	5	males	male	NNS
cord-010027-r0tl01kq	1027	6	and	and	CC
cord-010027-r0tl01kq	1027	7	5	5	CD
cord-010027-r0tl01kq	1027	8	females	female	NNS
cord-010027-r0tl01kq	1027	9	,	,	,
cord-010027-r0tl01kq	1027	10	with	with	IN
cord-010027-r0tl01kq	1027	11	an	an	DT
cord-010027-r0tl01kq	1027	12	age	age	NN
cord-010027-r0tl01kq	1027	13	range	range	NN
cord-010027-r0tl01kq	1027	14	of	of	IN
cord-010027-r0tl01kq	1027	15	32	32	CD
cord-010027-r0tl01kq	1027	16	-72	-72	NN
cord-010027-r0tl01kq	1028	1	(	(	-LRB-
cord-010027-r0tl01kq	1028	2	mean	mean	VB
cord-010027-r0tl01kq	1028	3	age	age	NN
cord-010027-r0tl01kq	1028	4	=	=	SYM
cord-010027-r0tl01kq	1028	5	57	57	CD
cord-010027-r0tl01kq	1028	6	years	year	NNS
cord-010027-r0tl01kq	1028	7	)	)	-RRB-
cord-010027-r0tl01kq	1028	8	.	.	.
cord-010027-r0tl01kq	1029	1	Unsuspected	unsuspected	JJ
cord-010027-r0tl01kq	1029	2	infectious	infectious	JJ
cord-010027-r0tl01kq	1029	3	diagnoses	diagnosis	NNS
cord-010027-r0tl01kq	1029	4	were	be	VBD
cord-010027-r0tl01kq	1029	5	made	make	VBN
cord-010027-r0tl01kq	1029	6	at	at	IN
cord-010027-r0tl01kq	1029	7	post	post	FW
cord-010027-r0tl01kq	1029	8	mortem	mortem	NN
cord-010027-r0tl01kq	1029	9	in	in	IN
cord-010027-r0tl01kq	1029	10	6	6	CD
cord-010027-r0tl01kq	1029	11	of	of	IN
cord-010027-r0tl01kq	1029	12	the	the	DT
cord-010027-r0tl01kq	1029	13	9	9	CD
cord-010027-r0tl01kq	1029	14	cases	case	NNS
cord-010027-r0tl01kq	1029	15	.	.	.
cord-010027-r0tl01kq	1030	1	Organs	organ	NNS
cord-010027-r0tl01kq	1030	2	affected	affect	VBD
cord-010027-r0tl01kq	1030	3	included	include	VBD
cord-010027-r0tl01kq	1030	4	lung	lung	NN
cord-010027-r0tl01kq	1030	5	(	(	-LRB-
cord-010027-r0tl01kq	1030	6	n	n	NN
cord-010027-r0tl01kq	1030	7	=	=	SYM
cord-010027-r0tl01kq	1030	8	5	5	CD
cord-010027-r0tl01kq	1030	9	)	)	-RRB-
cord-010027-r0tl01kq	1030	10	,	,	,
cord-010027-r0tl01kq	1030	11	brain	brain	NN
cord-010027-r0tl01kq	1030	12	(	(	-LRB-
cord-010027-r0tl01kq	1030	13	n	n	NN
cord-010027-r0tl01kq	1030	14	=	=	SYM
cord-010027-r0tl01kq	1030	15	1	1	CD
cord-010027-r0tl01kq	1030	16	)	)	-RRB-
cord-010027-r0tl01kq	1030	17	and	and	CC
cord-010027-r0tl01kq	1030	18	haematological	haematological	JJ
cord-010027-r0tl01kq	1030	19	system	system	NN
cord-010027-r0tl01kq	1030	20	(	(	-LRB-
cord-010027-r0tl01kq	1030	21	n	n	NN
cord-010027-r0tl01kq	1030	22	=	=	SYM
cord-010027-r0tl01kq	1030	23	1	1	CD
cord-010027-r0tl01kq	1030	24	)	)	-RRB-
cord-010027-r0tl01kq	1030	25	.	.	.
cord-010027-r0tl01kq	1031	1	In	in	IN
cord-010027-r0tl01kq	1031	2	one	one	CD
cord-010027-r0tl01kq	1031	3	case	case	NN
cord-010027-r0tl01kq	1031	4	both	both	DT
cord-010027-r0tl01kq	1031	5	colon	colon	NN
cord-010027-r0tl01kq	1031	6	and	and	CC
cord-010027-r0tl01kq	1031	7	lung	lung	NN
cord-010027-r0tl01kq	1031	8	were	be	VBD
cord-010027-r0tl01kq	1031	9	affected	affect	VBN
cord-010027-r0tl01kq	1031	10	(	(	-LRB-
cord-010027-r0tl01kq	1031	11	n=1	n=1	NN
cord-010027-r0tl01kq	1031	12	)	)	-RRB-
cord-010027-r0tl01kq	1031	13	and	and	CC
cord-010027-r0tl01kq	1031	14	in	in	IN
cord-010027-r0tl01kq	1031	15	a	a	DT
cord-010027-r0tl01kq	1031	16	further	further	JJ
cord-010027-r0tl01kq	1031	17	case	case	NN
cord-010027-r0tl01kq	1031	18	both	both	CC
cord-010027-r0tl01kq	1031	19	liver	liver	NN
cord-010027-r0tl01kq	1031	20	and	and	CC
cord-010027-r0tl01kq	1031	21	lung	lung	NN
cord-010027-r0tl01kq	1031	22	were	be	VBD
cord-010027-r0tl01kq	1031	23	affected	affect	VBN
cord-010027-r0tl01kq	1031	24	(	(	-LRB-
cord-010027-r0tl01kq	1031	25	n=1	n=1	JJ
cord-010027-r0tl01kq	1031	26	)	)	-RRB-
cord-010027-r0tl01kq	1031	27	.	.	.
cord-010027-r0tl01kq	1032	1	Immunohistochemistry	Immunohistochemistry	NNP
cord-010027-r0tl01kq	1032	2	and/or	and/or	CC
cord-010027-r0tl01kq	1032	3	histochemistry	histochemistry	NNP
cord-010027-r0tl01kq	1032	4	was	be	VBD
cord-010027-r0tl01kq	1032	5	invaluable	invaluable	JJ
cord-010027-r0tl01kq	1032	6	in	in	IN
cord-010027-r0tl01kq	1032	7	making	make	VBG
cord-010027-r0tl01kq	1032	8	the	the	DT
cord-010027-r0tl01kq	1032	9	diagnoses	diagnosis	NNS
cord-010027-r0tl01kq	1032	10	and	and	CC
cord-010027-r0tl01kq	1032	11	was	be	VBD
cord-010027-r0tl01kq	1032	12	used	use	VBN
cord-010027-r0tl01kq	1032	13	in	in	IN
cord-010027-r0tl01kq	1032	14	all	all	DT
cord-010027-r0tl01kq	1032	15	9	9	CD
cord-010027-r0tl01kq	1032	16	cases	case	NNS
cord-010027-r0tl01kq	1032	17	(	(	-LRB-
cord-010027-r0tl01kq	1032	18	n=9	n=9	NN
cord-010027-r0tl01kq	1032	19	)	)	-RRB-
cord-010027-r0tl01kq	1032	20	.	.	.
cord-010027-r0tl01kq	1033	1	Treatments	treatment	NNS
cord-010027-r0tl01kq	1033	2	leading	lead	VBG
cord-010027-r0tl01kq	1033	3	to	to	IN
cord-010027-r0tl01kq	1033	4	immunosuppression	immunosuppression	NN
cord-010027-r0tl01kq	1033	5	included	include	VBD
cord-010027-r0tl01kq	1033	6	chemotherapeutic	chemotherapeutic	JJ
cord-010027-r0tl01kq	1033	7	agents	agent	NNS
cord-010027-r0tl01kq	1033	8	,	,	,
cord-010027-r0tl01kq	1033	9	monoclonal	monoclonal	JJ
cord-010027-r0tl01kq	1033	10	antibodies	antibody	NNS
cord-010027-r0tl01kq	1033	11	,	,	,
cord-010027-r0tl01kq	1033	12	steroids	steroid	NNS
cord-010027-r0tl01kq	1033	13	and	and	CC
cord-010027-r0tl01kq	1033	14	methotrexate	methotrexate	NNP
cord-010027-r0tl01kq	1033	15	.	.	.
cord-010027-r0tl01kq	1034	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1034	2	believe	believe	VBP
cord-010027-r0tl01kq	1034	3	that	that	IN
cord-010027-r0tl01kq	1034	4	with	with	IN
cord-010027-r0tl01kq	1034	5	the	the	DT
cord-010027-r0tl01kq	1034	6	ever	ever	RB
cord-010027-r0tl01kq	1034	7	increasing	increase	VBG
cord-010027-r0tl01kq	1034	8	use	use	NN
cord-010027-r0tl01kq	1034	9	of	of	IN
cord-010027-r0tl01kq	1034	10	immunosuppressive	immunosuppressive	JJ
cord-010027-r0tl01kq	1034	11	therapies	therapy	NNS
cord-010027-r0tl01kq	1034	12	(	(	-LRB-
cord-010027-r0tl01kq	1034	13	both	both	DT
cord-010027-r0tl01kq	1034	14	new	new	JJ
cord-010027-r0tl01kq	1034	15	and	and	CC
cord-010027-r0tl01kq	1034	16	old	old	JJ
cord-010027-r0tl01kq	1034	17	)	)	-RRB-
cord-010027-r0tl01kq	1034	18	for	for	IN
cord-010027-r0tl01kq	1034	19	a	a	DT
cord-010027-r0tl01kq	1034	20	wider	wide	JJR
cord-010027-r0tl01kq	1034	21	number	number	NN
cord-010027-r0tl01kq	1034	22	of	of	IN
cord-010027-r0tl01kq	1034	23	disorders	disorder	NNS
cord-010027-r0tl01kq	1034	24	,	,	,
cord-010027-r0tl01kq	1034	25	vigilance	vigilance	NN
cord-010027-r0tl01kq	1034	26	should	should	MD
cord-010027-r0tl01kq	1034	27	be	be	VB
cord-010027-r0tl01kq	1034	28	paid	pay	VBN
cord-010027-r0tl01kq	1034	29	to	to	IN
cord-010027-r0tl01kq	1034	30	their	-PRON-	PRP$
cord-010027-r0tl01kq	1034	31	potential	potential	NN
cord-010027-r0tl01kq	1034	32	to	to	TO
cord-010027-r0tl01kq	1034	33	cause	cause	VB
cord-010027-r0tl01kq	1034	34	life	life	NN
cord-010027-r0tl01kq	1034	35	threatening	threaten	VBG
cord-010027-r0tl01kq	1034	36	side	side	NN
cord-010027-r0tl01kq	1034	37	effects	effect	NNS
cord-010027-r0tl01kq	1034	38	.	.	.
cord-010027-r0tl01kq	1035	1	Histopathologists	histopathologist	NNS
cord-010027-r0tl01kq	1035	2	play	play	VBP
cord-010027-r0tl01kq	1035	3	a	a	DT
cord-010027-r0tl01kq	1035	4	pivotal	pivotal	JJ
cord-010027-r0tl01kq	1035	5	role	role	NN
cord-010027-r0tl01kq	1035	6	in	in	IN
cord-010027-r0tl01kq	1035	7	the	the	DT
cord-010027-r0tl01kq	1035	8	recognition	recognition	NN
cord-010027-r0tl01kq	1035	9	of	of	IN
cord-010027-r0tl01kq	1035	10	this	this	DT
cord-010027-r0tl01kq	1035	11	risk	risk	NN
cord-010027-r0tl01kq	1035	12	and	and	CC
cord-010027-r0tl01kq	1035	13	in	in	IN
cord-010027-r0tl01kq	1035	14	the	the	DT
cord-010027-r0tl01kq	1035	15	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1035	16	of	of	IN
cord-010027-r0tl01kq	1035	17	these	these	DT
cord-010027-r0tl01kq	1035	18	diseases	disease	NNS
cord-010027-r0tl01kq	1035	19	.	.	.
cord-010027-r0tl01kq	1036	1	Audit	Audit	NNP
cord-010027-r0tl01kq	1036	2	of	of	IN
cord-010027-r0tl01kq	1036	3	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1036	4	-	-	HYPH
cord-010027-r0tl01kq	1036	5	Based	base	VBN
cord-010027-r0tl01kq	1036	6	Adult	Adult	NNP
cord-010027-r0tl01kq	1036	7	Autopsy	Autopsy	NNP
cord-010027-r0tl01kq	1036	8	Practice	Practice	NNP
cord-010027-r0tl01kq	1036	9	in	in	IN
cord-010027-r0tl01kq	1036	10	a	a	DT
cord-010027-r0tl01kq	1036	11	University	University	NNP
cord-010027-r0tl01kq	1036	12	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1036	13	from	from	IN
cord-010027-r0tl01kq	1036	14	July	July	NNP
cord-010027-r0tl01kq	1036	15	2013	2013	CD
cord-010027-r0tl01kq	1036	16	-	-	SYM
cord-010027-r0tl01kq	1036	17	2014	2014	CD
cord-010027-r0tl01kq	1036	18	P	p	NN
cord-010027-r0tl01kq	1036	19	D	D	NNP
cord-010027-r0tl01kq	1036	20	Abu	Abu	NNP
cord-010027-r0tl01kq	1036	21	-	-	HYPH
cord-010027-r0tl01kq	1036	22	Sinn	Sinn	NNP
cord-010027-r0tl01kq	1036	23	;	;	:
cord-010027-r0tl01kq	1037	1	F	F	NNP
cord-010027-r0tl01kq	1037	2	MacSweeney	MacSweeney	NNP
cord-010027-r0tl01kq	1038	1	The	the	DT
cord-010027-r0tl01kq	1038	2	contribution	contribution	NN
cord-010027-r0tl01kq	1038	3	of	of	IN
cord-010027-r0tl01kq	1038	4	hospital	hospital	NN
cord-010027-r0tl01kq	1038	5	-	-	HYPH
cord-010027-r0tl01kq	1038	6	based	base	VBN
cord-010027-r0tl01kq	1038	7	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1038	8	practice	practice	NN
cord-010027-r0tl01kq	1038	9	to	to	IN
cord-010027-r0tl01kq	1038	10	improvements	improvement	NNS
cord-010027-r0tl01kq	1038	11	in	in	IN
cord-010027-r0tl01kq	1038	12	patient	patient	JJ
cord-010027-r0tl01kq	1038	13	care	care	NN
cord-010027-r0tl01kq	1038	14	is	be	VBZ
cord-010027-r0tl01kq	1038	15	substantial	substantial	JJ
cord-010027-r0tl01kq	1038	16	;	;	:
cord-010027-r0tl01kq	1038	17	however	however	RB
cord-010027-r0tl01kq	1038	18	,	,	,
cord-010027-r0tl01kq	1038	19	there	there	EX
cord-010027-r0tl01kq	1038	20	remains	remain	VBZ
cord-010027-r0tl01kq	1038	21	a	a	DT
cord-010027-r0tl01kq	1038	22	void	void	NN
cord-010027-r0tl01kq	1038	23	in	in	IN
cord-010027-r0tl01kq	1038	24	the	the	DT
cord-010027-r0tl01kq	1038	25	processes	process	NNS
cord-010027-r0tl01kq	1038	26	of	of	IN
cord-010027-r0tl01kq	1038	27	audit	audit	NN
cord-010027-r0tl01kq	1038	28	and	and	CC
cord-010027-r0tl01kq	1038	29	raising	raise	VBG
cord-010027-r0tl01kq	1038	30	quality	quality	NN
cord-010027-r0tl01kq	1038	31	of	of	IN
cord-010027-r0tl01kq	1038	32	standards	standard	NNS
cord-010027-r0tl01kq	1038	33	in	in	IN
cord-010027-r0tl01kq	1038	34	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1038	35	services	service	NNS
cord-010027-r0tl01kq	1038	36	.	.	.
cord-010027-r0tl01kq	1039	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1039	2	aim	aim	VBP
cord-010027-r0tl01kq	1039	3	to	to	TO
cord-010027-r0tl01kq	1039	4	assess	assess	VB
cord-010027-r0tl01kq	1039	5	the	the	DT
cord-010027-r0tl01kq	1039	6	current	current	JJ
cord-010027-r0tl01kq	1039	7	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1039	8	practice	practice	NN
cord-010027-r0tl01kq	1039	9	compared	compare	VBN
cord-010027-r0tl01kq	1039	10	to	to	IN
cord-010027-r0tl01kq	1039	11	RCPath	RCPath	NNP
cord-010027-r0tl01kq	1039	12	guidelines	guideline	NNS
cord-010027-r0tl01kq	1039	13	and	and	CC
cord-010027-r0tl01kq	1039	14	identify	identify	VB
cord-010027-r0tl01kq	1039	15	areas	area	NNS
cord-010027-r0tl01kq	1039	16	for	for	IN
cord-010027-r0tl01kq	1039	17	achieving	achieve	VBG
cord-010027-r0tl01kq	1039	18	a	a	DT
cord-010027-r0tl01kq	1039	19	high	high	JJ
cord-010027-r0tl01kq	1039	20	quality	quality	NN
cord-010027-r0tl01kq	1039	21	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1039	22	service	service	NN
cord-010027-r0tl01kq	1039	23	.	.	.
cord-010027-r0tl01kq	1040	1	All	all	DT
cord-010027-r0tl01kq	1040	2	adult	adult	NN
cord-010027-r0tl01kq	1040	3	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1040	4	cases	case	NNS
cord-010027-r0tl01kq	1040	5	performed	perform	VBN
cord-010027-r0tl01kq	1040	6	at	at	IN
cord-010027-r0tl01kq	1040	7	a	a	DT
cord-010027-r0tl01kq	1040	8	university	university	NN
cord-010027-r0tl01kq	1040	9	hospital	hospital	NN
cord-010027-r0tl01kq	1040	10	mortuary	mortuary	NN
cord-010027-r0tl01kq	1040	11	between	between	IN
cord-010027-r0tl01kq	1040	12	July	July	NNP
cord-010027-r0tl01kq	1040	13	2013	2013	CD
cord-010027-r0tl01kq	1040	14	and	and	CC
cord-010027-r0tl01kq	1040	15	2014	2014	CD
cord-010027-r0tl01kq	1040	16	were	be	VBD
cord-010027-r0tl01kq	1040	17	reviewed	review	VBN
cord-010027-r0tl01kq	1040	18	.	.	.
cord-010027-r0tl01kq	1041	1	A	a	DT
cord-010027-r0tl01kq	1041	2	total	total	NN
cord-010027-r0tl01kq	1041	3	of	of	IN
cord-010027-r0tl01kq	1041	4	522	522	CD
cord-010027-r0tl01kq	1041	5	adult	adult	NN
cord-010027-r0tl01kq	1041	6	autopsies	autopsy	NNS
cord-010027-r0tl01kq	1041	7	were	be	VBD
cord-010027-r0tl01kq	1041	8	performed	perform	VBN
cord-010027-r0tl01kq	1041	9	by	by	IN
cord-010027-r0tl01kq	1041	10	5	5	CD
cord-010027-r0tl01kq	1041	11	Consultant	Consultant	NNP
cord-010027-r0tl01kq	1041	12	Histopathologists	Histopathologists	NNP
cord-010027-r0tl01kq	1041	13	.	.	.
cord-010027-r0tl01kq	1042	1	Ninety	ninety	CD
cord-010027-r0tl01kq	1042	2	nine	nine	CD
cord-010027-r0tl01kq	1042	3	percent	percent	NN
cord-010027-r0tl01kq	1042	4	were	be	VBD
cord-010027-r0tl01kq	1042	5	Coroners	coroner	NNS
cord-010027-r0tl01kq	1042	6	'	'	POS
cord-010027-r0tl01kq	1042	7	cases	case	NNS
cord-010027-r0tl01kq	1042	8	.	.	.
cord-010027-r0tl01kq	1043	1	The	the	DT
cord-010027-r0tl01kq	1043	2	median	median	JJ
cord-010027-r0tl01kq	1043	3	turnaround	turnaround	NN
cord-010027-r0tl01kq	1043	4	time	time	NN
cord-010027-r0tl01kq	1043	5	was	be	VBD
cord-010027-r0tl01kq	1043	6	38.5	38.5	CD
cord-010027-r0tl01kq	1043	7	days	day	NNS
cord-010027-r0tl01kq	1043	8	,	,	,
cord-010027-r0tl01kq	1043	9	with	with	IN
cord-010027-r0tl01kq	1043	10	a	a	DT
cord-010027-r0tl01kq	1043	11	range	range	NN
cord-010027-r0tl01kq	1043	12	of	of	IN
cord-010027-r0tl01kq	1043	13	3	3	CD
cord-010027-r0tl01kq	1043	14	-	-	SYM
cord-010027-r0tl01kq	1043	15	123	123	CD
cord-010027-r0tl01kq	1043	16	days	day	NNS
cord-010027-r0tl01kq	1043	17	,	,	,
cord-010027-r0tl01kq	1043	18	excluding	exclude	VBG
cord-010027-r0tl01kq	1043	19	31	31	CD
cord-010027-r0tl01kq	1043	20	outlier	outlier	JJ
cord-010027-r0tl01kq	1043	21	cases	case	NNS
cord-010027-r0tl01kq	1043	22	(	(	-LRB-
cord-010027-r0tl01kq	1043	23	complex	complex	JJ
cord-010027-r0tl01kq	1043	24	timeconsuming	timeconsuming	JJ
cord-010027-r0tl01kq	1043	25	cases	case	NNS
cord-010027-r0tl01kq	1043	26	)	)	-RRB-
cord-010027-r0tl01kq	1043	27	.	.	.
cord-010027-r0tl01kq	1044	1	There	there	EX
cord-010027-r0tl01kq	1044	2	was	be	VBD
cord-010027-r0tl01kq	1044	3	considerable	considerable	JJ
cord-010027-r0tl01kq	1044	4	variation	variation	NN
cord-010027-r0tl01kq	1044	5	in	in	IN
cord-010027-r0tl01kq	1044	6	turnaround	turnaround	NN
cord-010027-r0tl01kq	1044	7	times	time	NNS
cord-010027-r0tl01kq	1044	8	in	in	IN
cord-010027-r0tl01kq	1044	9	complex	complex	JJ
cord-010027-r0tl01kq	1044	10	cases	case	NNS
cord-010027-r0tl01kq	1044	11	and	and	CC
cord-010027-r0tl01kq	1044	12	between	between	IN
cord-010027-r0tl01kq	1044	13	the	the	DT
cord-010027-r0tl01kq	1044	14	various	various	JJ
cord-010027-r0tl01kq	1044	15	reporting	reporting	NN
cord-010027-r0tl01kq	1044	16	pathologists	pathologist	NNS
cord-010027-r0tl01kq	1044	17	.	.	.
cord-010027-r0tl01kq	1045	1	Eighty	eighty	CD
cord-010027-r0tl01kq	1045	2	five	five	CD
cord-010027-r0tl01kq	1045	3	percent	percent	NN
cord-010027-r0tl01kq	1045	4	of	of	IN
cord-010027-r0tl01kq	1045	5	cases	case	NNS
cord-010027-r0tl01kq	1045	6	were	be	VBD
cord-010027-r0tl01kq	1045	7	compliant	compliant	JJ
cord-010027-r0tl01kq	1045	8	with	with	IN
cord-010027-r0tl01kq	1045	9	RCPath	RCPath	NNP
cord-010027-r0tl01kq	1045	10	Minimum	Minimum	NNP
cord-010027-r0tl01kq	1045	11	Dataset	Dataset	NNP
cord-010027-r0tl01kq	1045	12	for	for	IN
cord-010027-r0tl01kq	1045	13	Autopsy	Autopsy	NNP
cord-010027-r0tl01kq	1045	14	Practice	Practice	NNP
cord-010027-r0tl01kq	1045	15	.	.	.
cord-010027-r0tl01kq	1046	1	The	the	DT
cord-010027-r0tl01kq	1046	2	remainder	remainder	NN
cord-010027-r0tl01kq	1046	3	were	be	VBD
cord-010027-r0tl01kq	1046	4	lacking	lack	VBG
cord-010027-r0tl01kq	1046	5	clinical	clinical	JJ
cord-010027-r0tl01kq	1046	6	information	information	NN
cord-010027-r0tl01kq	1046	7	only	only	RB
cord-010027-r0tl01kq	1046	8	.	.	.
cord-010027-r0tl01kq	1047	1	Histology	histology	NN
cord-010027-r0tl01kq	1047	2	and	and	CC
cord-010027-r0tl01kq	1047	3	toxicology	toxicology	NN
cord-010027-r0tl01kq	1047	4	contributed	contribute	VBD
cord-010027-r0tl01kq	1047	5	to	to	TO
cord-010027-r0tl01kq	1047	6	cause	cause	VB
cord-010027-r0tl01kq	1047	7	of	of	IN
cord-010027-r0tl01kq	1047	8	death	death	NN
cord-010027-r0tl01kq	1047	9	in	in	IN
cord-010027-r0tl01kq	1047	10	34.4	34.4	CD
cord-010027-r0tl01kq	1047	11	%	%	NN
cord-010027-r0tl01kq	1047	12	and	and	CC
cord-010027-r0tl01kq	1047	13	14.8	14.8	CD
cord-010027-r0tl01kq	1047	14	%	%	NN
cord-010027-r0tl01kq	1047	15	respectively	respectively	RB
cord-010027-r0tl01kq	1047	16	.	.	.
cord-010027-r0tl01kq	1048	1	No	no	DT
cord-010027-r0tl01kq	1048	2	organs	organ	NNS
cord-010027-r0tl01kq	1048	3	were	be	VBD
cord-010027-r0tl01kq	1048	4	retained	retain	VBN
cord-010027-r0tl01kq	1048	5	.	.	.
cord-010027-r0tl01kq	1049	1	Further	further	JJ
cord-010027-r0tl01kq	1049	2	review	review	NN
cord-010027-r0tl01kq	1049	3	of	of	IN
cord-010027-r0tl01kq	1049	4	the	the	DT
cord-010027-r0tl01kq	1049	5	cases	case	NNS
cord-010027-r0tl01kq	1049	6	not	not	RB
cord-010027-r0tl01kq	1049	7	compliant	compliant	JJ
cord-010027-r0tl01kq	1049	8	with	with	IN
cord-010027-r0tl01kq	1049	9	RCPath	RCPath	NNP
cord-010027-r0tl01kq	1049	10	guidelines	guideline	NNS
cord-010027-r0tl01kq	1049	11	(	(	-LRB-
cord-010027-r0tl01kq	1049	12	15	15	CD
cord-010027-r0tl01kq	1049	13	%	%	NN
cord-010027-r0tl01kq	1049	14	)	)	-RRB-
cord-010027-r0tl01kq	1049	15	,	,	,
cord-010027-r0tl01kq	1049	16	identified	identify	VBD
cord-010027-r0tl01kq	1049	17	that	that	IN
cord-010027-r0tl01kq	1049	18	the	the	DT
cord-010027-r0tl01kq	1049	19	possible	possible	JJ
cord-010027-r0tl01kq	1049	20	reasons	reason	NNS
cord-010027-r0tl01kq	1049	21	were	be	VBD
cord-010027-r0tl01kq	1049	22	the	the	DT
cord-010027-r0tl01kq	1049	23	inaccuracy	inaccuracy	NN
cord-010027-r0tl01kq	1049	24	,	,	,
cord-010027-r0tl01kq	1049	25	and	and	CC
cord-010027-r0tl01kq	1049	26	sometimes	sometimes	RB
cord-010027-r0tl01kq	1049	27	irrelevance	irrelevance	NN
cord-010027-r0tl01kq	1049	28	to	to	IN
cord-010027-r0tl01kq	1049	29	the	the	DT
cord-010027-r0tl01kq	1049	30	cause	cause	NN
cord-010027-r0tl01kq	1049	31	of	of	IN
cord-010027-r0tl01kq	1049	32	death	death	NN
cord-010027-r0tl01kq	1049	33	,	,	,
cord-010027-r0tl01kq	1049	34	of	of	IN
cord-010027-r0tl01kq	1049	35	the	the	DT
cord-010027-r0tl01kq	1049	36	information	information	NN
cord-010027-r0tl01kq	1049	37	received	receive	VBN
cord-010027-r0tl01kq	1049	38	by	by	IN
cord-010027-r0tl01kq	1049	39	the	the	DT
cord-010027-r0tl01kq	1049	40	pathologists	pathologist	NNS
cord-010027-r0tl01kq	1049	41	.	.	.
cord-010027-r0tl01kq	1050	1	In	in	IN
cord-010027-r0tl01kq	1050	2	many	many	JJ
cord-010027-r0tl01kq	1050	3	instances	instance	NNS
cord-010027-r0tl01kq	1050	4	,	,	,
cord-010027-r0tl01kq	1050	5	the	the	DT
cord-010027-r0tl01kq	1050	6	clinical	clinical	JJ
cord-010027-r0tl01kq	1050	7	information	information	NN
cord-010027-r0tl01kq	1050	8	given	give	VBN
cord-010027-r0tl01kq	1050	9	to	to	IN
cord-010027-r0tl01kq	1050	10	the	the	DT
cord-010027-r0tl01kq	1050	11	pathologist	pathologist	NN
cord-010027-r0tl01kq	1050	12	may	may	MD
cord-010027-r0tl01kq	1050	13	be	be	VB
cord-010027-r0tl01kq	1050	14	controversial	controversial	JJ
cord-010027-r0tl01kq	1050	15	,	,	,
cord-010027-r0tl01kq	1050	16	and	and	CC
cord-010027-r0tl01kq	1050	17	a	a	DT
cord-010027-r0tl01kq	1050	18	certain	certain	JJ
cord-010027-r0tl01kq	1050	19	degree	degree	NN
cord-010027-r0tl01kq	1050	20	of	of	IN
cord-010027-r0tl01kq	1050	21	caution	caution	NN
cord-010027-r0tl01kq	1050	22	needs	need	VBZ
cord-010027-r0tl01kq	1050	23	to	to	TO
cord-010027-r0tl01kq	1050	24	be	be	VB
cord-010027-r0tl01kq	1050	25	implemented	implement	VBN
cord-010027-r0tl01kq	1050	26	to	to	TO
cord-010027-r0tl01kq	1050	27	avoid	avoid	VB
cord-010027-r0tl01kq	1050	28	including	include	VBG
cord-010027-r0tl01kq	1050	29	misleading	mislead	VBG
cord-010027-r0tl01kq	1050	30	information	information	NN
cord-010027-r0tl01kq	1050	31	in	in	IN
cord-010027-r0tl01kq	1050	32	the	the	DT
cord-010027-r0tl01kq	1050	33	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1050	34	report	report	NN
cord-010027-r0tl01kq	1050	35	.	.	.
cord-010027-r0tl01kq	1051	1	The	the	DT
cord-010027-r0tl01kq	1051	2	turnaround	turnaround	NN
cord-010027-r0tl01kq	1051	3	times	time	NNS
cord-010027-r0tl01kq	1051	4	could	could	MD
cord-010027-r0tl01kq	1051	5	be	be	VB
cord-010027-r0tl01kq	1051	6	improved	improve	VBN
cord-010027-r0tl01kq	1051	7	if	if	IN
cord-010027-r0tl01kq	1051	8	a	a	DT
cord-010027-r0tl01kq	1051	9	preliminary	preliminary	JJ
cord-010027-r0tl01kq	1051	10	report	report	NN
cord-010027-r0tl01kq	1051	11	is	be	VBZ
cord-010027-r0tl01kq	1051	12	issued	issue	VBN
cord-010027-r0tl01kq	1051	13	within	within	IN
cord-010027-r0tl01kq	1051	14	a	a	DT
cord-010027-r0tl01kq	1051	15	set	set	VBN
cord-010027-r0tl01kq	1051	16	time	time	NN
cord-010027-r0tl01kq	1051	17	frame	frame	NN
cord-010027-r0tl01kq	1051	18	,	,	,
cord-010027-r0tl01kq	1051	19	to	to	TO
cord-010027-r0tl01kq	1051	20	be	be	VB
cord-010027-r0tl01kq	1051	21	followed	follow	VBN
cord-010027-r0tl01kq	1051	22	by	by	IN
cord-010027-r0tl01kq	1051	23	the	the	DT
cord-010027-r0tl01kq	1051	24	complete	complete	JJ
cord-010027-r0tl01kq	1051	25	report	report	NN
cord-010027-r0tl01kq	1051	26	when	when	WRB
cord-010027-r0tl01kq	1051	27	the	the	DT
cord-010027-r0tl01kq	1051	28	histology	histology	NN
cord-010027-r0tl01kq	1051	29	and	and	CC
cord-010027-r0tl01kq	1051	30	toxicology	toxicology	NN
cord-010027-r0tl01kq	1051	31	results	result	NNS
cord-010027-r0tl01kq	1051	32	are	be	VBP
cord-010027-r0tl01kq	1051	33	available	available	JJ
cord-010027-r0tl01kq	1051	34	.	.	.
cord-010027-r0tl01kq	1052	1	However	however	RB
cord-010027-r0tl01kq	1052	2	,	,	,
cord-010027-r0tl01kq	1052	3	this	this	DT
cord-010027-r0tl01kq	1052	4	practice	practice	NN
cord-010027-r0tl01kq	1052	5	is	be	VBZ
cord-010027-r0tl01kq	1052	6	not	not	RB
cord-010027-r0tl01kq	1052	7	acceptable	acceptable	JJ
cord-010027-r0tl01kq	1052	8	to	to	IN
cord-010027-r0tl01kq	1052	9	some	some	DT
cord-010027-r0tl01kq	1052	10	coroners	coroner	NNS
cord-010027-r0tl01kq	1052	11	who	who	WP
cord-010027-r0tl01kq	1052	12	prefer	prefer	VBP
cord-010027-r0tl01kq	1052	13	one	one	CD
cord-010027-r0tl01kq	1052	14	complete	complete	JJ
cord-010027-r0tl01kq	1052	15	final	final	JJ
cord-010027-r0tl01kq	1052	16	report	report	NN
cord-010027-r0tl01kq	1052	17	.	.	.
cord-010027-r0tl01kq	1053	1	Variations	variation	NNS
cord-010027-r0tl01kq	1053	2	in	in	IN
cord-010027-r0tl01kq	1053	3	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1053	4	practice	practice	NN
cord-010027-r0tl01kq	1053	5	are	be	VBP
cord-010027-r0tl01kq	1053	6	to	to	TO
cord-010027-r0tl01kq	1053	7	be	be	VB
cord-010027-r0tl01kq	1053	8	expected	expect	VBN
cord-010027-r0tl01kq	1053	9	as	as	IN
cord-010027-r0tl01kq	1053	10	each	each	DT
cord-010027-r0tl01kq	1053	11	autopsy	autopsy	JJ
cord-010027-r0tl01kq	1053	12	involves	involve	VBZ
cord-010027-r0tl01kq	1053	13	substantial	substantial	JJ
cord-010027-r0tl01kq	1053	14	case	case	NN
cord-010027-r0tl01kq	1053	15	-	-	HYPH
cord-010027-r0tl01kq	1053	16	specific	specific	JJ
cord-010027-r0tl01kq	1053	17	information	information	NN
cord-010027-r0tl01kq	1053	18	to	to	IN
cord-010027-r0tl01kq	1053	19	which	which	WDT
cord-010027-r0tl01kq	1053	20	a	a	DT
cord-010027-r0tl01kq	1053	21	case	case	NN
cord-010027-r0tl01kq	1053	22	-	-	HYPH
cord-010027-r0tl01kq	1053	23	specific	specific	JJ
cord-010027-r0tl01kq	1053	24	answer	answer	NN
cord-010027-r0tl01kq	1053	25	to	to	IN
cord-010027-r0tl01kq	1053	26	the	the	DT
cord-010027-r0tl01kq	1053	27	cause	cause	NN
cord-010027-r0tl01kq	1053	28	of	of	IN
cord-010027-r0tl01kq	1053	29	death	death	NN
cord-010027-r0tl01kq	1053	30	is	be	VBZ
cord-010027-r0tl01kq	1053	31	expected	expect	VBN
cord-010027-r0tl01kq	1053	32	.	.	.
cord-010027-r0tl01kq	1054	1	Prostate	prostate	NN
cord-010027-r0tl01kq	1054	2	cancer	cancer	NN
cord-010027-r0tl01kq	1054	3	is	be	VBZ
cord-010027-r0tl01kq	1054	4	the	the	DT
cord-010027-r0tl01kq	1054	5	second	second	JJ
cord-010027-r0tl01kq	1054	6	most	most	RBS
cord-010027-r0tl01kq	1054	7	common	common	JJ
cord-010027-r0tl01kq	1054	8	form	form	NN
cord-010027-r0tl01kq	1054	9	of	of	IN
cord-010027-r0tl01kq	1054	10	cancer	cancer	NN
cord-010027-r0tl01kq	1054	11	in	in	IN
cord-010027-r0tl01kq	1054	12	males	male	NNS
cord-010027-r0tl01kq	1054	13	,	,	,
cord-010027-r0tl01kq	1054	14	and	and	CC
cord-010027-r0tl01kq	1054	15	the	the	DT
cord-010027-r0tl01kq	1054	16	incidence	incidence	NN
cord-010027-r0tl01kq	1054	17	of	of	IN
cord-010027-r0tl01kq	1054	18	this	this	DT
cord-010027-r0tl01kq	1054	19	disease	disease	NN
cord-010027-r0tl01kq	1054	20	is	be	VBZ
cord-010027-r0tl01kq	1054	21	predicted	predict	VBN
cord-010027-r0tl01kq	1054	22	to	to	TO
cord-010027-r0tl01kq	1054	23	double	double	VB
cord-010027-r0tl01kq	1054	24	globally	globally	RB
cord-010027-r0tl01kq	1054	25	by	by	IN
cord-010027-r0tl01kq	1054	26	2030	2030	CD
cord-010027-r0tl01kq	1054	27	.	.	.
cord-010027-r0tl01kq	1055	1	More	More	JJR
cord-010027-r0tl01kq	1055	2	than	than	IN
cord-010027-r0tl01kq	1055	3	1.1	1.1	CD
cord-010027-r0tl01kq	1055	4	million	million	CD
cord-010027-r0tl01kq	1055	5	new	new	JJ
cord-010027-r0tl01kq	1055	6	cases	case	NNS
cord-010027-r0tl01kq	1055	7	of	of	IN
cord-010027-r0tl01kq	1055	8	prostate	prostate	NN
cord-010027-r0tl01kq	1055	9	cancer	cancer	NN
cord-010027-r0tl01kq	1055	10	are	be	VBP
cord-010027-r0tl01kq	1055	11	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1055	12	each	each	DT
cord-010027-r0tl01kq	1055	13	year	year	NN
cord-010027-r0tl01kq	1055	14	and	and	CC
cord-010027-r0tl01kq	1056	1	two	two	CD
cord-010027-r0tl01kq	1056	2	thirds	third	NNS
cord-010027-r0tl01kq	1056	3	of	of	IN
cord-010027-r0tl01kq	1056	4	these	these	DT
cord-010027-r0tl01kq	1056	5	patients	patient	NNS
cord-010027-r0tl01kq	1056	6	are	be	VBP
cord-010027-r0tl01kq	1056	7	from	from	IN
cord-010027-r0tl01kq	1056	8	the	the	DT
cord-010027-r0tl01kq	1056	9	Western	western	JJ
cord-010027-r0tl01kq	1056	10	world	world	NN
cord-010027-r0tl01kq	1056	11	.	.	.
cord-010027-r0tl01kq	1057	1	The	the	DT
cord-010027-r0tl01kq	1057	2	current	current	JJ
cord-010027-r0tl01kq	1057	3	PSA	PSA	NNP
cord-010027-r0tl01kq	1057	4	-	-	HYPH
cord-010027-r0tl01kq	1057	5	based	base	VBN
cord-010027-r0tl01kq	1057	6	test	test	NN
cord-010027-r0tl01kq	1057	7	for	for	IN
cord-010027-r0tl01kq	1057	8	the	the	DT
cord-010027-r0tl01kq	1057	9	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1057	10	of	of	IN
cord-010027-r0tl01kq	1057	11	prostate	prostate	NN
cord-010027-r0tl01kq	1057	12	cancer	cancer	NN
cord-010027-r0tl01kq	1057	13	lacks	lack	VBZ
cord-010027-r0tl01kq	1057	14	specificity	specificity	NN
cord-010027-r0tl01kq	1057	15	,	,	,
cord-010027-r0tl01kq	1057	16	results	result	NNS
cord-010027-r0tl01kq	1057	17	in	in	IN
cord-010027-r0tl01kq	1057	18	missed	miss	VBN
cord-010027-r0tl01kq	1057	19	-	-	HYPH
cord-010027-r0tl01kq	1057	20	diagnoses	diagnosis	NNS
cord-010027-r0tl01kq	1057	21	,	,	,
cord-010027-r0tl01kq	1057	22	over	over	IN
cord-010027-r0tl01kq	1057	23	-	-	HYPH
cord-010027-r0tl01kq	1057	24	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1057	25	and	and	CC
cord-010027-r0tl01kq	1057	26	unnecessary	unnecessary	JJ
cord-010027-r0tl01kq	1057	27	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1057	28	/	/	SYM
cord-010027-r0tl01kq	1057	29	treatment	treatment	NN
cord-010027-r0tl01kq	1057	30	.	.	.
cord-010027-r0tl01kq	1058	1	There	there	EX
cord-010027-r0tl01kq	1058	2	is	be	VBZ
cord-010027-r0tl01kq	1058	3	an	an	DT
cord-010027-r0tl01kq	1058	4	urgent	urgent	JJ
cord-010027-r0tl01kq	1058	5	need	need	NN
cord-010027-r0tl01kq	1058	6	for	for	IN
cord-010027-r0tl01kq	1058	7	a	a	DT
cord-010027-r0tl01kq	1058	8	method	method	NN
cord-010027-r0tl01kq	1058	9	that	that	WDT
cord-010027-r0tl01kq	1058	10	enables	enable	VBZ
cord-010027-r0tl01kq	1058	11	early	early	JJ
cord-010027-r0tl01kq	1058	12	accurate	accurate	JJ
cord-010027-r0tl01kq	1058	13	detection	detection	NN
cord-010027-r0tl01kq	1058	14	of	of	IN
cord-010027-r0tl01kq	1058	15	prostate	prostate	NN
cord-010027-r0tl01kq	1058	16	cancer	cancer	NN
cord-010027-r0tl01kq	1058	17	.	.	.
cord-010027-r0tl01kq	1059	1	Endosomes	Endosomes	NNP
cord-010027-r0tl01kq	1059	2	and	and	CC
cord-010027-r0tl01kq	1059	3	lysosomes	lysosome	NNS
cord-010027-r0tl01kq	1059	4	are	be	VBP
cord-010027-r0tl01kq	1059	5	cellular	cellular	JJ
cord-010027-r0tl01kq	1059	6	compartments	compartment	NNS
cord-010027-r0tl01kq	1059	7	that	that	WDT
cord-010027-r0tl01kq	1059	8	degrade	degrade	VBP
cord-010027-r0tl01kq	1059	9	and	and	CC
cord-010027-r0tl01kq	1059	10	turnover	turnover	NN
cord-010027-r0tl01kq	1059	11	macromolecules	macromolecule	NNS
cord-010027-r0tl01kq	1059	12	in	in	IN
cord-010027-r0tl01kq	1059	13	order	order	NN
cord-010027-r0tl01kq	1059	14	to	to	TO
cord-010027-r0tl01kq	1059	15	maintain	maintain	VB
cord-010027-r0tl01kq	1059	16	cellular	cellular	JJ
cord-010027-r0tl01kq	1059	17	homeostasis	homeostasis	NN
cord-010027-r0tl01kq	1059	18	.	.	.
cord-010027-r0tl01kq	1060	1	These	these	DT
cord-010027-r0tl01kq	1060	2	organelles	organelle	NNS
cord-010027-r0tl01kq	1060	3	are	be	VBP
cord-010027-r0tl01kq	1060	4	directly	directly	RB
cord-010027-r0tl01kq	1060	5	involved	involve	VBN
cord-010027-r0tl01kq	1060	6	in	in	IN
cord-010027-r0tl01kq	1060	7	the	the	DT
cord-010027-r0tl01kq	1060	8	critical	critical	JJ
cord-010027-r0tl01kq	1060	9	processes	process	NNS
cord-010027-r0tl01kq	1060	10	of	of	IN
cord-010027-r0tl01kq	1060	11	energy	energy	NN
cord-010027-r0tl01kq	1060	12	metabolism	metabolism	NN
cord-010027-r0tl01kq	1060	13	,	,	,
cord-010027-r0tl01kq	1060	14	cell	cell	NN
cord-010027-r0tl01kq	1060	15	division	division	NN
cord-010027-r0tl01kq	1060	16	,	,	,
cord-010027-r0tl01kq	1060	17	and	and	CC
cord-010027-r0tl01kq	1060	18	intracellular	intracellular	JJ
cord-010027-r0tl01kq	1060	19	signalling	signalling	NN
cord-010027-r0tl01kq	1060	20	,	,	,
cord-010027-r0tl01kq	1060	21	which	which	WDT
cord-010027-r0tl01kq	1060	22	are	be	VBP
cord-010027-r0tl01kq	1060	23	all	all	DT
cord-010027-r0tl01kq	1060	24	hallmarks	hallmark	NNS
cord-010027-r0tl01kq	1060	25	of	of	IN
cord-010027-r0tl01kq	1060	26	cancer	cancer	NN
cord-010027-r0tl01kq	1060	27	pathogenesis	pathogenesis	NN
cord-010027-r0tl01kq	1060	28	.	.	.
cord-010027-r0tl01kq	1061	1	Endosomes	endosome	NNS
cord-010027-r0tl01kq	1061	2	have	have	VBP
cord-010027-r0tl01kq	1061	3	a	a	DT
cord-010027-r0tl01kq	1061	4	critical	critical	JJ
cord-010027-r0tl01kq	1061	5	role	role	NN
cord-010027-r0tl01kq	1061	6	in	in	IN
cord-010027-r0tl01kq	1061	7	controlling	control	VBG
cord-010027-r0tl01kq	1061	8	the	the	DT
cord-010027-r0tl01kq	1061	9	secretion	secretion	NN
cord-010027-r0tl01kq	1061	10	of	of	IN
cord-010027-r0tl01kq	1061	11	proteins	protein	NNS
cord-010027-r0tl01kq	1061	12	into	into	IN
cord-010027-r0tl01kq	1061	13	extracellular	extracellular	JJ
cord-010027-r0tl01kq	1061	14	fluids	fluid	NNS
cord-010027-r0tl01kq	1061	15	,	,	,
cord-010027-r0tl01kq	1061	16	making	make	VBG
cord-010027-r0tl01kq	1061	17	them	-PRON-	PRP
cord-010027-r0tl01kq	1061	18	an	an	DT
cord-010027-r0tl01kq	1061	19	ideal	ideal	JJ
cord-010027-r0tl01kq	1061	20	system	system	NN
cord-010027-r0tl01kq	1061	21	to	to	TO
cord-010027-r0tl01kq	1061	22	identify	identify	VB
cord-010027-r0tl01kq	1061	23	new	new	JJ
cord-010027-r0tl01kq	1061	24	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1061	25	that	that	WDT
cord-010027-r0tl01kq	1061	26	are	be	VBP
cord-010027-r0tl01kq	1061	27	released	release	VBN
cord-010027-r0tl01kq	1061	28	from	from	IN
cord-010027-r0tl01kq	1061	29	cancer	cancer	NN
cord-010027-r0tl01kq	1061	30	cells	cell	NNS
cord-010027-r0tl01kq	1061	31	.	.	.
cord-010027-r0tl01kq	1062	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1062	2	have	have	VBP
cord-010027-r0tl01kq	1062	3	discovered	discover	VBN
cord-010027-r0tl01kq	1062	4	that	that	IN
cord-010027-r0tl01kq	1062	5	endosome	endosome	NN
cord-010027-r0tl01kq	1062	6	biogenesis	biogenesis	NN
cord-010027-r0tl01kq	1062	7	(	(	-LRB-
cord-010027-r0tl01kq	1062	8	formation	formation	NN
cord-010027-r0tl01kq	1062	9	and	and	CC
cord-010027-r0tl01kq	1062	10	function	function	NN
cord-010027-r0tl01kq	1062	11	of	of	IN
cord-010027-r0tl01kq	1062	12	endosomes	endosome	NNS
cord-010027-r0tl01kq	1062	13	)	)	-RRB-
cord-010027-r0tl01kq	1062	14	is	be	VBZ
cord-010027-r0tl01kq	1062	15	altered	alter	VBN
cord-010027-r0tl01kq	1062	16	in	in	IN
cord-010027-r0tl01kq	1062	17	prostate	prostate	NN
cord-010027-r0tl01kq	1062	18	cancer	cancer	NN
cord-010027-r0tl01kq	1062	19	.	.	.
cord-010027-r0tl01kq	1063	1	There	there	EX
cord-010027-r0tl01kq	1063	2	were	be	VBD
cord-010027-r0tl01kq	1063	3	significant	significant	JJ
cord-010027-r0tl01kq	1063	4	changes	change	NNS
cord-010027-r0tl01kq	1063	5	in	in	IN
cord-010027-r0tl01kq	1063	6	the	the	DT
cord-010027-r0tl01kq	1063	7	gene	gene	NN
cord-010027-r0tl01kq	1063	8	and	and	CC
cord-010027-r0tl01kq	1063	9	protein	protein	NN
cord-010027-r0tl01kq	1063	10	expression	expression	NN
cord-010027-r0tl01kq	1063	11	for	for	IN
cord-010027-r0tl01kq	1063	12	19	19	CD
cord-010027-r0tl01kq	1063	13	endosomal	endosomal	NNP
cord-010027-r0tl01kq	1063	14	proteins	protein	NNS
cord-010027-r0tl01kq	1063	15	and	and	CC
cord-010027-r0tl01kq	1063	16	differential	differential	JJ
cord-010027-r0tl01kq	1063	17	distribution	distribution	NN
cord-010027-r0tl01kq	1063	18	of	of	IN
cord-010027-r0tl01kq	1063	19	endosome	endosome	NN
cord-010027-r0tl01kq	1063	20	subsets	subset	NNS
cord-010027-r0tl01kq	1063	21	in	in	IN
cord-010027-r0tl01kq	1063	22	prostate	prostate	NN
cord-010027-r0tl01kq	1063	23	cancer	cancer	NN
cord-010027-r0tl01kq	1063	24	cell	cell	NN
cord-010027-r0tl01kq	1063	25	lines	line	NNS
cord-010027-r0tl01kq	1063	26	.	.	.
cord-010027-r0tl01kq	1064	1	There	there	EX
cord-010027-r0tl01kq	1064	2	were	be	VBD
cord-010027-r0tl01kq	1064	3	also	also	RB
cord-010027-r0tl01kq	1064	4	changes	change	NNS
cord-010027-r0tl01kq	1064	5	to	to	IN
cord-010027-r0tl01kq	1064	6	the	the	DT
cord-010027-r0tl01kq	1064	7	endosomal	endosomal	NNP
cord-010027-r0tl01kq	1064	8	traffic	traffic	NN
cord-010027-r0tl01kq	1064	9	and	and	CC
cord-010027-r0tl01kq	1064	10	signalling	signalling	NN
cord-010027-r0tl01kq	1064	11	of	of	IN
cord-010027-r0tl01kq	1064	12	the	the	DT
cord-010027-r0tl01kq	1064	13	transferrin	transferrin	NN
cord-010027-r0tl01kq	1064	14	receptor	receptor	NN
cord-010027-r0tl01kq	1064	15	in	in	IN
cord-010027-r0tl01kq	1064	16	prostate	prostate	NN
cord-010027-r0tl01kq	1064	17	cancer	cancer	NN
cord-010027-r0tl01kq	1064	18	cells	cell	NNS
cord-010027-r0tl01kq	1064	19	.	.	.
cord-010027-r0tl01kq	1065	1	These	these	DT
cord-010027-r0tl01kq	1065	2	fundamental	fundamental	JJ
cord-010027-r0tl01kq	1065	3	changes	change	NNS
cord-010027-r0tl01kq	1065	4	in	in	IN
cord-010027-r0tl01kq	1065	5	the	the	DT
cord-010027-r0tl01kq	1065	6	cell	cell	NN
cord-010027-r0tl01kq	1065	7	biology	biology	NN
cord-010027-r0tl01kq	1065	8	of	of	IN
cord-010027-r0tl01kq	1065	9	prostate	prostate	NN
cord-010027-r0tl01kq	1065	10	cancer	cancer	NN
cord-010027-r0tl01kq	1065	11	have	have	VBP
cord-010027-r0tl01kq	1065	12	allowed	allow	VBN
cord-010027-r0tl01kq	1065	13	us	-PRON-	PRP
cord-010027-r0tl01kq	1065	14	to	to	TO
cord-010027-r0tl01kq	1065	15	identify	identify	VB
cord-010027-r0tl01kq	1065	16	a	a	DT
cord-010027-r0tl01kq	1065	17	specific	specific	JJ
cord-010027-r0tl01kq	1065	18	set	set	NN
cord-010027-r0tl01kq	1065	19	of	of	IN
cord-010027-r0tl01kq	1065	20	endosomal	endosomal	JJ
cord-010027-r0tl01kq	1065	21	proteins	protein	NNS
cord-010027-r0tl01kq	1065	22	that	that	WDT
cord-010027-r0tl01kq	1065	23	have	have	VBP
cord-010027-r0tl01kq	1065	24	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1065	25	potential	potential	NN
cord-010027-r0tl01kq	1065	26	.	.	.
cord-010027-r0tl01kq	1066	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1066	2	are	be	VBP
cord-010027-r0tl01kq	1066	3	developing	develop	VBG
cord-010027-r0tl01kq	1066	4	ELISA	ELISA	NNP
cord-010027-r0tl01kq	1066	5	's	's	POS
cord-010027-r0tl01kq	1066	6	to	to	TO
cord-010027-r0tl01kq	1066	7	quantify	quantify	VB
cord-010027-r0tl01kq	1066	8	these	these	DT
cord-010027-r0tl01kq	1066	9	endosomal	endosomal	JJ
cord-010027-r0tl01kq	1066	10	proteins	protein	NNS
cord-010027-r0tl01kq	1066	11	in	in	IN
cord-010027-r0tl01kq	1066	12	patient	patient	NN
cord-010027-r0tl01kq	1066	13	samples	sample	NNS
cord-010027-r0tl01kq	1066	14	and	and	CC
cord-010027-r0tl01kq	1066	15	antibodies	antibody	NNS
cord-010027-r0tl01kq	1066	16	for	for	IN
cord-010027-r0tl01kq	1066	17	immune	immune	JJ
cord-010027-r0tl01kq	1066	18	histology	histology	NN
cord-010027-r0tl01kq	1066	19	applications	application	NNS
cord-010027-r0tl01kq	1066	20	.	.	.
cord-010027-r0tl01kq	1067	1	The	the	DT
cord-010027-r0tl01kq	1067	2	objective	objective	NN
cord-010027-r0tl01kq	1067	3	for	for	IN
cord-010027-r0tl01kq	1067	4	this	this	DT
cord-010027-r0tl01kq	1067	5	project	project	NN
cord-010027-r0tl01kq	1067	6	is	be	VBZ
cord-010027-r0tl01kq	1067	7	to	to	TO
cord-010027-r0tl01kq	1067	8	develop	develop	VB
cord-010027-r0tl01kq	1067	9	an	an	DT
cord-010027-r0tl01kq	1067	10	effective	effective	JJ
cord-010027-r0tl01kq	1067	11	method	method	NN
cord-010027-r0tl01kq	1067	12	for	for	IN
cord-010027-r0tl01kq	1067	13	the	the	DT
cord-010027-r0tl01kq	1067	14	early	early	JJ
cord-010027-r0tl01kq	1067	15	and	and	CC
cord-010027-r0tl01kq	1067	16	specific	specific	JJ
cord-010027-r0tl01kq	1067	17	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1067	18	of	of	IN
cord-010027-r0tl01kq	1067	19	prostate	prostate	NN
cord-010027-r0tl01kq	1067	20	cancer	cancer	NN
cord-010027-r0tl01kq	1067	21	,	,	,
cord-010027-r0tl01kq	1067	22	which	which	WDT
cord-010027-r0tl01kq	1067	23	is	be	VBZ
cord-010027-r0tl01kq	1067	24	important	important	JJ
cord-010027-r0tl01kq	1067	25	as	as	IN
cord-010027-r0tl01kq	1067	26	this	this	DT
cord-010027-r0tl01kq	1067	27	will	will	MD
cord-010027-r0tl01kq	1067	28	have	have	VB
cord-010027-r0tl01kq	1067	29	a	a	DT
cord-010027-r0tl01kq	1067	30	major	major	JJ
cord-010027-r0tl01kq	1067	31	impact	impact	NN
cord-010027-r0tl01kq	1067	32	on	on	IN
cord-010027-r0tl01kq	1067	33	patient	patient	JJ
cord-010027-r0tl01kq	1067	34	outcome	outcome	NN
cord-010027-r0tl01kq	1067	35	and	and	CC
cord-010027-r0tl01kq	1067	36	survival	survival	NN
cord-010027-r0tl01kq	1067	37	.	.	.
cord-010027-r0tl01kq	1068	1	The	the	DT
cord-010027-r0tl01kq	1068	2	incidence	incidence	NN
cord-010027-r0tl01kq	1068	3	of	of	IN
cord-010027-r0tl01kq	1068	4	malignant	malignant	JJ
cord-010027-r0tl01kq	1068	5	melanoma	melanoma	NN
cord-010027-r0tl01kq	1068	6	has	have	VBZ
cord-010027-r0tl01kq	1068	7	rapidly	rapidly	RB
cord-010027-r0tl01kq	1068	8	increased	increase	VBN
cord-010027-r0tl01kq	1068	9	in	in	IN
cord-010027-r0tl01kq	1068	10	recent	recent	JJ
cord-010027-r0tl01kq	1068	11	times	time	NNS
cord-010027-r0tl01kq	1068	12	and	and	CC
cord-010027-r0tl01kq	1068	13	melanoma	melanoma	NN
cord-010027-r0tl01kq	1068	14	currently	currently	RB
cord-010027-r0tl01kq	1068	15	represents	represent	VBZ
cord-010027-r0tl01kq	1068	16	the	the	DT
cord-010027-r0tl01kq	1068	17	second	second	JJ
cord-010027-r0tl01kq	1068	18	most	most	RBS
cord-010027-r0tl01kq	1068	19	common	common	JJ
cord-010027-r0tl01kq	1068	20	cancer	cancer	NN
cord-010027-r0tl01kq	1068	21	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1068	22	in	in	IN
cord-010027-r0tl01kq	1068	23	young	young	JJ
cord-010027-r0tl01kq	1068	24	adults	adult	NNS
cord-010027-r0tl01kq	1068	25	.	.	.
cord-010027-r0tl01kq	1069	1	Diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1069	2	is	be	VBZ
cord-010027-r0tl01kq	1069	3	based	base	VBN
cord-010027-r0tl01kq	1069	4	predominantly	predominantly	RB
cord-010027-r0tl01kq	1069	5	on	on	IN
cord-010027-r0tl01kq	1069	6	histological	histological	JJ
cord-010027-r0tl01kq	1069	7	assessment	assessment	NN
cord-010027-r0tl01kq	1069	8	;	;	:
cord-010027-r0tl01kq	1069	9	however	however	RB
cord-010027-r0tl01kq	1069	10	,	,	,
cord-010027-r0tl01kq	1069	11	due	due	IN
cord-010027-r0tl01kq	1069	12	to	to	IN
cord-010027-r0tl01kq	1069	13	the	the	DT
cord-010027-r0tl01kq	1069	14	wide	wide	JJ
cord-010027-r0tl01kq	1069	15	spectrum	spectrum	NN
cord-010027-r0tl01kq	1069	16	of	of	IN
cord-010027-r0tl01kq	1069	17	morphological	morphological	JJ
cord-010027-r0tl01kq	1069	18	characteristics	characteristic	NNS
cord-010027-r0tl01kq	1069	19	and	and	CC
cord-010027-r0tl01kq	1069	20	lack	lack	NN
cord-010027-r0tl01kq	1069	21	of	of	IN
cord-010027-r0tl01kq	1069	22	firm	firm	JJ
cord-010027-r0tl01kq	1069	23	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1069	24	criteria	criterion	NNS
cord-010027-r0tl01kq	1069	25	,	,	,
cord-010027-r0tl01kq	1069	26	accurate	accurate	JJ
cord-010027-r0tl01kq	1069	27	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1069	28	can	can	MD
cord-010027-r0tl01kq	1069	29	be	be	VB
cord-010027-r0tl01kq	1069	30	challenging	challenging	JJ
cord-010027-r0tl01kq	1069	31	.	.	.
cord-010027-r0tl01kq	1070	1	Some	some	DT
cord-010027-r0tl01kq	1070	2	atypical	atypical	JJ
cord-010027-r0tl01kq	1070	3	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	1070	4	lesions	lesion	NNS
cord-010027-r0tl01kq	1070	5	do	do	VBP
cord-010027-r0tl01kq	1070	6	not	not	RB
cord-010027-r0tl01kq	1070	7	display	display	VB
cord-010027-r0tl01kq	1070	8	clear	clear	RB
cord-010027-r0tl01kq	1070	9	-	-	HYPH
cord-010027-r0tl01kq	1070	10	cut	cut	VBN
cord-010027-r0tl01kq	1070	11	morphological	morphological	JJ
cord-010027-r0tl01kq	1070	12	features	feature	NNS
cord-010027-r0tl01kq	1070	13	to	to	TO
cord-010027-r0tl01kq	1070	14	allow	allow	VB
cord-010027-r0tl01kq	1070	15	distinction	distinction	NN
cord-010027-r0tl01kq	1070	16	of	of	IN
cord-010027-r0tl01kq	1070	17	benign	benign	JJ
cord-010027-r0tl01kq	1070	18	from	from	IN
cord-010027-r0tl01kq	1070	19	malignant	malignant	JJ
cord-010027-r0tl01kq	1070	20	tumours	tumour	NNS
cord-010027-r0tl01kq	1070	21	,	,	,
cord-010027-r0tl01kq	1070	22	making	make	VBG
cord-010027-r0tl01kq	1070	23	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1070	24	and	and	CC
cord-010027-r0tl01kq	1070	25	treatment	treatment	NN
cord-010027-r0tl01kq	1070	26	difficult	difficult	JJ
cord-010027-r0tl01kq	1070	27	.	.	.
cord-010027-r0tl01kq	1071	1	Among	among	IN
cord-010027-r0tl01kq	1071	2	these	these	DT
cord-010027-r0tl01kq	1071	3	atypical	atypical	JJ
cord-010027-r0tl01kq	1071	4	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	1071	5	lesions	lesion	NNS
cord-010027-r0tl01kq	1071	6	blue	blue	JJ
cord-010027-r0tl01kq	1071	7	nevi	nevus	NNS
cord-010027-r0tl01kq	1071	8	,	,	,
cord-010027-r0tl01kq	1071	9	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1071	10	nevi	nevus	NNS
cord-010027-r0tl01kq	1071	11	and	and	CC
cord-010027-r0tl01kq	1071	12	dysplastic	dysplastic	JJ
cord-010027-r0tl01kq	1071	13	lesions	lesion	NNS
cord-010027-r0tl01kq	1071	14	are	be	VBP
cord-010027-r0tl01kq	1071	15	common	common	JJ
cord-010027-r0tl01kq	1071	16	.	.	.
cord-010027-r0tl01kq	1072	1	From	from	IN
cord-010027-r0tl01kq	1072	2	histological	histological	JJ
cord-010027-r0tl01kq	1072	3	features	feature	NNS
cord-010027-r0tl01kq	1072	4	alone	alone	RB
cord-010027-r0tl01kq	1072	5	,	,	,
cord-010027-r0tl01kq	1072	6	it	-PRON-	PRP
cord-010027-r0tl01kq	1072	7	can	can	MD
cord-010027-r0tl01kq	1072	8	be	be	VB
cord-010027-r0tl01kq	1072	9	difficult	difficult	JJ
cord-010027-r0tl01kq	1072	10	to	to	TO
cord-010027-r0tl01kq	1072	11	exclude	exclude	VB
cord-010027-r0tl01kq	1072	12	a	a	DT
cord-010027-r0tl01kq	1072	13	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1072	14	of	of	IN
cord-010027-r0tl01kq	1072	15	melanoma	melanoma	NN
cord-010027-r0tl01kq	1072	16	and	and	CC
cord-010027-r0tl01kq	1072	17	therefore	therefore	RB
cord-010027-r0tl01kq	1072	18	aggressive	aggressive	JJ
cord-010027-r0tl01kq	1072	19	surgical	surgical	JJ
cord-010027-r0tl01kq	1072	20	strategies	strategy	NNS
cord-010027-r0tl01kq	1072	21	may	may	MD
cord-010027-r0tl01kq	1072	22	be	be	VB
cord-010027-r0tl01kq	1072	23	employed	employ	VBN
cord-010027-r0tl01kq	1072	24	in	in	IN
cord-010027-r0tl01kq	1072	25	cases	case	NNS
cord-010027-r0tl01kq	1072	26	were	be	VBD
cord-010027-r0tl01kq	1072	27	they	-PRON-	PRP
cord-010027-r0tl01kq	1072	28	are	be	VBP
cord-010027-r0tl01kq	1072	29	unnecessary	unnecessary	JJ
cord-010027-r0tl01kq	1072	30	,	,	,
cord-010027-r0tl01kq	1072	31	highlighting	highlight	VBG
cord-010027-r0tl01kq	1072	32	the	the	DT
cord-010027-r0tl01kq	1072	33	need	need	NN
cord-010027-r0tl01kq	1072	34	for	for	IN
cord-010027-r0tl01kq	1072	35	improved	improve	VBN
cord-010027-r0tl01kq	1072	36	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1072	37	techniques	technique	NNS
cord-010027-r0tl01kq	1072	38	.	.	.
cord-010027-r0tl01kq	1073	1	Both	both	DT
cord-010027-r0tl01kq	1073	2	mRNA	mRNA	NNP
cord-010027-r0tl01kq	1073	3	and	and	CC
cord-010027-r0tl01kq	1073	4	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1073	5	profiling	profiling	NN
cord-010027-r0tl01kq	1073	6	have	have	VBP
cord-010027-r0tl01kq	1073	7	been	be	VBN
cord-010027-r0tl01kq	1073	8	shown	show	VBN
cord-010027-r0tl01kq	1073	9	to	to	TO
cord-010027-r0tl01kq	1073	10	be	be	VB
cord-010027-r0tl01kq	1073	11	able	able	JJ
cord-010027-r0tl01kq	1073	12	to	to	TO
cord-010027-r0tl01kq	1073	13	distinguish	distinguish	VB
cord-010027-r0tl01kq	1073	14	benign	benign	JJ
cord-010027-r0tl01kq	1073	15	nevi	nevus	NNS
cord-010027-r0tl01kq	1073	16	and	and	CC
cord-010027-r0tl01kq	1073	17	primary	primary	JJ
cord-010027-r0tl01kq	1073	18	melanoma	melanoma	NN
cord-010027-r0tl01kq	1073	19	tumours	tumour	NNS
cord-010027-r0tl01kq	1073	20	.	.	.
cord-010027-r0tl01kq	1074	1	Studying	study	VBG
cord-010027-r0tl01kq	1074	2	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1074	3	expression	expression	NN
cord-010027-r0tl01kq	1074	4	levels	level	NNS
cord-010027-r0tl01kq	1074	5	is	be	VBZ
cord-010027-r0tl01kq	1074	6	an	an	DT
cord-010027-r0tl01kq	1074	7	attractive	attractive	JJ
cord-010027-r0tl01kq	1074	8	strategy	strategy	NN
cord-010027-r0tl01kq	1074	9	as	as	IN
cord-010027-r0tl01kq	1074	10	miRNAs	miRNAs	NNP
cord-010027-r0tl01kq	1074	11	are	be	VBP
cord-010027-r0tl01kq	1074	12	highly	highly	RB
cord-010027-r0tl01kq	1074	13	resistant	resistant	JJ
cord-010027-r0tl01kq	1074	14	to	to	IN
cord-010027-r0tl01kq	1074	15	degradation	degradation	NN
cord-010027-r0tl01kq	1074	16	and	and	CC
cord-010027-r0tl01kq	1074	17	can	can	MD
cord-010027-r0tl01kq	1074	18	be	be	VB
cord-010027-r0tl01kq	1074	19	easily	easily	RB
cord-010027-r0tl01kq	1074	20	analysed	analyse	VBN
cord-010027-r0tl01kq	1074	21	in	in	IN
cord-010027-r0tl01kq	1074	22	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1074	23	samples	sample	NNS
cord-010027-r0tl01kq	1074	24	.	.	.
cord-010027-r0tl01kq	1075	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1075	2	have	have	VBP
cord-010027-r0tl01kq	1075	3	studied	study	VBN
cord-010027-r0tl01kq	1075	4	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1075	5	expression	expression	NN
cord-010027-r0tl01kq	1075	6	levels	level	NNS
cord-010027-r0tl01kq	1075	7	in	in	IN
cord-010027-r0tl01kq	1075	8	a	a	DT
cord-010027-r0tl01kq	1075	9	cohort	cohort	NN
cord-010027-r0tl01kq	1075	10	of	of	IN
cord-010027-r0tl01kq	1075	11	benign	benign	JJ
cord-010027-r0tl01kq	1075	12	,	,	,
cord-010027-r0tl01kq	1075	13	blue	blue	JJ
cord-010027-r0tl01kq	1075	14	,	,	,
cord-010027-r0tl01kq	1075	15	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1075	16	and	and	CC
cord-010027-r0tl01kq	1075	17	dysplastic	dysplastic	JJ
cord-010027-r0tl01kq	1075	18	nevi	nevus	NNS
cord-010027-r0tl01kq	1075	19	versus	versus	IN
cord-010027-r0tl01kq	1075	20	primary	primary	JJ
cord-010027-r0tl01kq	1075	21	melanoma	melanoma	NN
cord-010027-r0tl01kq	1075	22	tumours	tumour	NNS
cord-010027-r0tl01kq	1075	23	and	and	CC
cord-010027-r0tl01kq	1075	24	their	-PRON-	PRP$
cord-010027-r0tl01kq	1075	25	derived	derive	VBN
cord-010027-r0tl01kq	1075	26	metastases	metastasis	NNS
cord-010027-r0tl01kq	1075	27	.	.	.
cord-010027-r0tl01kq	1076	1	Expression	expression	NN
cord-010027-r0tl01kq	1076	2	levels	level	NNS
cord-010027-r0tl01kq	1076	3	of	of	IN
cord-010027-r0tl01kq	1076	4	key	key	JJ
cord-010027-r0tl01kq	1076	5	melanoma	melanoma	NN
cord-010027-r0tl01kq	1076	6	miRNAs	miRNAs	NNP
cord-010027-r0tl01kq	1076	7	,	,	,
cord-010027-r0tl01kq	1076	8	including	include	VBG
cord-010027-r0tl01kq	1076	9	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1076	10	21	21	CD
cord-010027-r0tl01kq	1076	11	,	,	,
cord-010027-r0tl01kq	1076	12	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1076	13	211	211	CD
cord-010027-r0tl01kq	1076	14	,	,	,
cord-010027-r0tl01kq	1076	15	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1076	16	205	205	CD
cord-010027-r0tl01kq	1077	1	and	and	CC
cord-010027-r0tl01kq	1077	2	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1077	3	200c	200c	NNP
cord-010027-r0tl01kq	1077	4	can	can	MD
cord-010027-r0tl01kq	1077	5	be	be	VB
cord-010027-r0tl01kq	1077	6	used	use	VBN
cord-010027-r0tl01kq	1077	7	to	to	TO
cord-010027-r0tl01kq	1077	8	distinguish	distinguish	VB
cord-010027-r0tl01kq	1077	9	between	between	IN
cord-010027-r0tl01kq	1077	10	nevi	nevus	NNS
cord-010027-r0tl01kq	1077	11	and	and	CC
cord-010027-r0tl01kq	1077	12	malignant	malignant	JJ
cord-010027-r0tl01kq	1077	13	melanomas	melanoma	NNS
cord-010027-r0tl01kq	1077	14	.	.	.
cord-010027-r0tl01kq	1078	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1078	2	propose	propose	VBP
cord-010027-r0tl01kq	1078	3	an	an	DT
cord-010027-r0tl01kq	1078	4	easy	easy	NN
cord-010027-r0tl01kq	1078	5	to	to	TO
cord-010027-r0tl01kq	1078	6	implement	implement	VB
cord-010027-r0tl01kq	1078	7	,	,	,
cord-010027-r0tl01kq	1078	8	simple	simple	JJ
cord-010027-r0tl01kq	1078	9	and	and	CC
cord-010027-r0tl01kq	1078	10	robust	robust	JJ
cord-010027-r0tl01kq	1078	11	molecular	molecular	JJ
cord-010027-r0tl01kq	1078	12	method	method	NN
cord-010027-r0tl01kq	1078	13	based	base	VBN
cord-010027-r0tl01kq	1078	14	on	on	IN
cord-010027-r0tl01kq	1078	15	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1078	16	expression	expression	NN
cord-010027-r0tl01kq	1078	17	ratio	ratio	NN
cord-010027-r0tl01kq	1078	18	that	that	WDT
cord-010027-r0tl01kq	1078	19	,	,	,
cord-010027-r0tl01kq	1078	20	in	in	IN
cord-010027-r0tl01kq	1078	21	combination	combination	NN
cord-010027-r0tl01kq	1078	22	with	with	IN
cord-010027-r0tl01kq	1078	23	histological	histological	JJ
cord-010027-r0tl01kq	1078	24	assessment	assessment	NN
cord-010027-r0tl01kq	1078	25	,	,	,
cord-010027-r0tl01kq	1078	26	allows	allow	VBZ
cord-010027-r0tl01kq	1078	27	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1078	28	of	of	IN
cord-010027-r0tl01kq	1078	29	difficult	difficult	JJ
cord-010027-r0tl01kq	1078	30	to	to	TO
cord-010027-r0tl01kq	1078	31	classify	classify	VB
cord-010027-r0tl01kq	1078	32	atypical	atypical	JJ
cord-010027-r0tl01kq	1078	33	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	1078	34	lesions	lesion	NNS
cord-010027-r0tl01kq	1078	35	.	.	.
cord-010027-r0tl01kq	1079	1	Background	background	NN
cord-010027-r0tl01kq	1079	2	:	:	:
cord-010027-r0tl01kq	1080	1	Diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1080	2	of	of	IN
cord-010027-r0tl01kq	1080	3	Lynch	Lynch	NNP
cord-010027-r0tl01kq	1080	4	syndrome	syndrome	NN
cord-010027-r0tl01kq	1080	5	(	(	-LRB-
cord-010027-r0tl01kq	1080	6	LS	LS	NNP
cord-010027-r0tl01kq	1080	7	)	)	-RRB-
cord-010027-r0tl01kq	1080	8	traditionally	traditionally	RB
cord-010027-r0tl01kq	1080	9	relies	rely	VBZ
cord-010027-r0tl01kq	1080	10	on	on	IN
cord-010027-r0tl01kq	1080	11	clinical	clinical	JJ
cord-010027-r0tl01kq	1080	12	criteria	criterion	NNS
cord-010027-r0tl01kq	1080	13	to	to	TO
cord-010027-r0tl01kq	1080	14	guide	guide	VB
cord-010027-r0tl01kq	1080	15	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1080	16	genetic	genetic	JJ
cord-010027-r0tl01kq	1080	17	testing	testing	NN
cord-010027-r0tl01kq	1080	18	.	.	.
cord-010027-r0tl01kq	1081	1	MMR	MMR	NNP
cord-010027-r0tl01kq	1081	2	status	status	NN
cord-010027-r0tl01kq	1081	3	of	of	IN
cord-010027-r0tl01kq	1081	4	the	the	DT
cord-010027-r0tl01kq	1081	5	patient	patient	NN
cord-010027-r0tl01kq	1081	6	's	's	POS
cord-010027-r0tl01kq	1081	7	tumour	tumour	NN
cord-010027-r0tl01kq	1081	8	can	can	MD
cord-010027-r0tl01kq	1081	9	help	help	VB
cord-010027-r0tl01kq	1081	10	detect	detect	VB
cord-010027-r0tl01kq	1081	11	Lynch	Lynch	NNP
cord-010027-r0tl01kq	1081	12	syndrome	syndrome	NN
cord-010027-r0tl01kq	1081	13	families	family	NNS
cord-010027-r0tl01kq	1081	14	as	as	RB
cord-010027-r0tl01kq	1081	15	well	well	RB
cord-010027-r0tl01kq	1081	16	as	as	IN
cord-010027-r0tl01kq	1081	17	having	have	VBG
cord-010027-r0tl01kq	1081	18	other	other	JJ
cord-010027-r0tl01kq	1081	19	recognised	recognise	VBN
cord-010027-r0tl01kq	1081	20	applications	application	NNS
cord-010027-r0tl01kq	1081	21	for	for	IN
cord-010027-r0tl01kq	1081	22	the	the	DT
cord-010027-r0tl01kq	1081	23	patient	patient	NN
cord-010027-r0tl01kq	1081	24	's	's	POS
cord-010027-r0tl01kq	1081	25	management	management	NN
cord-010027-r0tl01kq	1081	26	including	include	VBG
cord-010027-r0tl01kq	1081	27	prognostic	prognostic	JJ
cord-010027-r0tl01kq	1081	28	and	and	CC
cord-010027-r0tl01kq	1081	29	predictive	predictive	JJ
cord-010027-r0tl01kq	1081	30	significance	significance	NN
cord-010027-r0tl01kq	1081	31	.	.	.
cord-010027-r0tl01kq	1082	1	As	as	IN
cord-010027-r0tl01kq	1082	2	such	such	JJ
cord-010027-r0tl01kq	1082	3	,	,	,
cord-010027-r0tl01kq	1082	4	the	the	DT
cord-010027-r0tl01kq	1082	5	'	'	``
cord-010027-r0tl01kq	1082	6	Dataset	Dataset	NNP
cord-010027-r0tl01kq	1082	7	for	for	IN
cord-010027-r0tl01kq	1082	8	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1082	9	cancer	cancer	NN
cord-010027-r0tl01kq	1082	10	histopathology	histopathology	NN
cord-010027-r0tl01kq	1082	11	report	report	NN
cord-010027-r0tl01kq	1082	12	'	'	POS
cord-010027-r0tl01kq	1082	13	recommendations	recommendation	NNS
cord-010027-r0tl01kq	1082	14	from	from	IN
cord-010027-r0tl01kq	1082	15	the	the	DT
cord-010027-r0tl01kq	1082	16	Royal	Royal	NNP
cord-010027-r0tl01kq	1082	17	college	college	NN
cord-010027-r0tl01kq	1082	18	of	of	IN
cord-010027-r0tl01kq	1082	19	pathologists	pathologist	NNS
cord-010027-r0tl01kq	1082	20	were	be	VBD
cord-010027-r0tl01kq	1082	21	updated	update	VBN
cord-010027-r0tl01kq	1082	22	in	in	IN
cord-010027-r0tl01kq	1082	23	July	July	NNP
cord-010027-r0tl01kq	1082	24	2014	2014	CD
cord-010027-r0tl01kq	1082	25	to	to	TO
cord-010027-r0tl01kq	1082	26	include	include	VB
cord-010027-r0tl01kq	1082	27	screening	screening	NN
cord-010027-r0tl01kq	1082	28	of	of	IN
cord-010027-r0tl01kq	1082	29	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1082	30	cancer	cancer	NN
cord-010027-r0tl01kq	1082	31	patients	patient	NNS
cord-010027-r0tl01kq	1082	32	under	under	IN
cord-010027-r0tl01kq	1082	33	the	the	DT
cord-010027-r0tl01kq	1082	34	age	age	NN
cord-010027-r0tl01kq	1082	35	of	of	IN
cord-010027-r0tl01kq	1082	36	50	50	CD
cord-010027-r0tl01kq	1082	37	and	and	CC
cord-010027-r0tl01kq	1082	38	molecular	molecular	JJ
cord-010027-r0tl01kq	1082	39	testing	testing	NN
cord-010027-r0tl01kq	1082	40	for	for	IN
cord-010027-r0tl01kq	1082	41	abnormalities	abnormality	NNS
cord-010027-r0tl01kq	1082	42	in	in	IN
cord-010027-r0tl01kq	1082	43	the	the	DT
cord-010027-r0tl01kq	1082	44	mismatch	mismatch	NN
cord-010027-r0tl01kq	1082	45	repair	repair	NN
cord-010027-r0tl01kq	1082	46	genes	gene	NNS
cord-010027-r0tl01kq	1082	47	.	.	.
cord-010027-r0tl01kq	1083	1	In	in	IN
cord-010027-r0tl01kq	1083	2	South	South	NNP
cord-010027-r0tl01kq	1083	3	-	-	HYPH
cord-010027-r0tl01kq	1083	4	East	East	NNP
cord-010027-r0tl01kq	1083	5	of	of	IN
cord-010027-r0tl01kq	1083	6	Scotland	Scotland	NNP
cord-010027-r0tl01kq	1083	7	we	-PRON-	PRP
cord-010027-r0tl01kq	1083	8	introduced	introduce	VBD
cord-010027-r0tl01kq	1083	9	molecular	molecular	JJ
cord-010027-r0tl01kq	1083	10	testing	testing	NN
cord-010027-r0tl01kq	1083	11	to	to	TO
cord-010027-r0tl01kq	1083	12	identify	identify	VB
cord-010027-r0tl01kq	1083	13	individuals	individual	NNS
cord-010027-r0tl01kq	1083	14	at	at	IN
cord-010027-r0tl01kq	1083	15	risk	risk	NN
cord-010027-r0tl01kq	1083	16	of	of	IN
cord-010027-r0tl01kq	1083	17	LS	LS	NNP
cord-010027-r0tl01kq	1083	18	.	.	.
cord-010027-r0tl01kq	1084	1	To	to	TO
cord-010027-r0tl01kq	1084	2	widen	widen	VB
cord-010027-r0tl01kq	1084	3	our	-PRON-	PRP$
cord-010027-r0tl01kq	1084	4	screening	screening	NN
cord-010027-r0tl01kq	1084	5	in	in	IN
cord-010027-r0tl01kq	1084	6	line	line	NN
cord-010027-r0tl01kq	1084	7	with	with	IN
cord-010027-r0tl01kq	1084	8	revised	revise	VBN
cord-010027-r0tl01kq	1084	9	guidelines	guideline	NNS
cord-010027-r0tl01kq	1084	10	set	set	VBN
cord-010027-r0tl01kq	1084	11	by	by	IN
cord-010027-r0tl01kq	1084	12	European	european	JJ
cord-010027-r0tl01kq	1084	13	experts	expert	NNS
cord-010027-r0tl01kq	1084	14	,	,	,
cord-010027-r0tl01kq	1084	15	we	-PRON-	PRP
cord-010027-r0tl01kq	1084	16	expanded	expand	VBD
cord-010027-r0tl01kq	1084	17	our	-PRON-	PRP$
cord-010027-r0tl01kq	1084	18	cohort	cohort	NN
cord-010027-r0tl01kq	1084	19	criteria	criterion	NNS
cord-010027-r0tl01kq	1084	20	to	to	TO
cord-010027-r0tl01kq	1084	21	include	include	VB
cord-010027-r0tl01kq	1084	22	those	those	DT
cord-010027-r0tl01kq	1084	23	between	between	IN
cord-010027-r0tl01kq	1084	24	the	the	DT
cord-010027-r0tl01kq	1084	25	age	age	NN
cord-010027-r0tl01kq	1084	26	of	of	IN
cord-010027-r0tl01kq	1084	27	50	50	CD
cord-010027-r0tl01kq	1084	28	and	and	CC
cord-010027-r0tl01kq	1084	29	60	60	CD
cord-010027-r0tl01kq	1084	30	.	.	.
cord-010027-r0tl01kq	1085	1	Methods	method	NNS
cord-010027-r0tl01kq	1085	2	:	:	:
cord-010027-r0tl01kq	1086	1	Molecular	molecular	JJ
cord-010027-r0tl01kq	1086	2	analysis	analysis	NN
cord-010027-r0tl01kq	1086	3	was	be	VBD
cord-010027-r0tl01kq	1086	4	carried	carry	VBN
cord-010027-r0tl01kq	1086	5	out	out	RP
cord-010027-r0tl01kq	1086	6	on	on	IN
cord-010027-r0tl01kq	1086	7	553	553	CD
cord-010027-r0tl01kq	1086	8	individuals	individual	NNS
cord-010027-r0tl01kq	1086	9	:	:	:
cord-010027-r0tl01kq	1086	10	446	446	CD
cord-010027-r0tl01kq	1086	11	via	via	IN
cord-010027-r0tl01kq	1086	12	'	'	``
cord-010027-r0tl01kq	1086	13	reflex	reflex	NN
cord-010027-r0tl01kq	1086	14	testing	testing	NN
cord-010027-r0tl01kq	1086	15	'	'	''
cord-010027-r0tl01kq	1086	16	(	(	-LRB-
cord-010027-r0tl01kq	1086	17	newly	newly	RB
cord-010027-r0tl01kq	1086	18	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1086	19	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1086	20	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1087	1	≤60	≤60	RB
cord-010027-r0tl01kq	1088	1	yrs	yr	NNS
cord-010027-r0tl01kq	1088	2	,	,	,
cord-010027-r0tl01kq	1088	3	or	or	CC
cord-010027-r0tl01kq	1088	4	clinical/	clinical/	CD
cord-010027-r0tl01kq	1088	5	pathological	pathological	JJ
cord-010027-r0tl01kq	1088	6	features	feature	NNS
cord-010027-r0tl01kq	1088	7	associated	associate	VBN
cord-010027-r0tl01kq	1088	8	with	with	IN
cord-010027-r0tl01kq	1088	9	MMR	MMR	NNP
cord-010027-r0tl01kq	1088	10	defects	defect	NNS
cord-010027-r0tl01kq	1088	11	,	,	,
cord-010027-r0tl01kq	1088	12	such	such	JJ
cord-010027-r0tl01kq	1088	13	as	as	IN
cord-010027-r0tl01kq	1088	14	pre	pre	JJ
cord-010027-r0tl01kq	1088	15	-	-	JJ
cord-010027-r0tl01kq	1088	16	menopausal	menopausal	JJ
cord-010027-r0tl01kq	1088	17	endometrial	endometrial	JJ
cord-010027-r0tl01kq	1088	18	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1088	19	,	,	,
cord-010027-r0tl01kq	1088	20	multiple	multiple	JJ
cord-010027-r0tl01kq	1088	21	tumours	tumour	NNS
cord-010027-r0tl01kq	1088	22	and	and	CC
cord-010027-r0tl01kq	1088	23	medullary	medullary	JJ
cord-010027-r0tl01kq	1088	24	-	-	HYPH
cord-010027-r0tl01kq	1088	25	type	type	NN
cord-010027-r0tl01kq	1088	26	carcinomas	carcinoma	NNS
cord-010027-r0tl01kq	1088	27	)	)	-RRB-
cord-010027-r0tl01kq	1088	28	and	and	CC
cord-010027-r0tl01kq	1089	1	107	107	CD
cord-010027-r0tl01kq	1089	2	via	via	IN
cord-010027-r0tl01kq	1089	3	'	'	''
cord-010027-r0tl01kq	1089	4	request	request	NN
cord-010027-r0tl01kq	1089	5	testing	testing	NN
cord-010027-r0tl01kq	1089	6	'	'	''
cord-010027-r0tl01kq	1089	7	(	(	-LRB-
cord-010027-r0tl01kq	1089	8	clinical	clinical	JJ
cord-010027-r0tl01kq	1089	9	criteria	criterion	NNS
cord-010027-r0tl01kq	1089	10	and	and	CC
cord-010027-r0tl01kq	1089	11	referral	referral	JJ
cord-010027-r0tl01kq	1089	12	dependent	dependent	NN
cord-010027-r0tl01kq	1089	13	)	)	-RRB-
cord-010027-r0tl01kq	1089	14	.	.	.
cord-010027-r0tl01kq	1089	15	'	'	''
cord-010027-r0tl01kq	1090	1	Molecular	molecular	JJ
cord-010027-r0tl01kq	1090	2	-	-	HYPH
cord-010027-r0tl01kq	1090	3	positive	positive	JJ
cord-010027-r0tl01kq	1090	4	'	'	''
cord-010027-r0tl01kq	1090	5	profiles	profile	NNS
cord-010027-r0tl01kq	1090	6	for	for	IN
cord-010027-r0tl01kq	1090	7	LS	LS	NNP
cord-010027-r0tl01kq	1090	8	were	be	VBD
cord-010027-r0tl01kq	1090	9	identified	identify	VBN
cord-010027-r0tl01kq	1090	10	for	for	IN
cord-010027-r0tl01kq	1090	11	genetic	genetic	JJ
cord-010027-r0tl01kq	1090	12	pre	pre	JJ
cord-010027-r0tl01kq	1090	13	-	-	JJ
cord-010027-r0tl01kq	1090	14	testing	testing	JJ
cord-010027-r0tl01kq	1090	15	counselling	counselling	NN
cord-010027-r0tl01kq	1090	16	/	/	SYM
cord-010027-r0tl01kq	1090	17	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1090	18	testing	testing	NN
cord-010027-r0tl01kq	1090	19	.	.	.
cord-010027-r0tl01kq	1091	1	Results	result	NNS
cord-010027-r0tl01kq	1091	2	:	:	:
cord-010027-r0tl01kq	1092	1	41	41	CD
cord-010027-r0tl01kq	1092	2	patients	patient	NNS
cord-010027-r0tl01kq	1092	3	with	with	IN
cord-010027-r0tl01kq	1092	4	potential	potential	JJ
cord-010027-r0tl01kq	1092	5	LS	ls	NN
cord-010027-r0tl01kq	1092	6	were	be	VBD
cord-010027-r0tl01kq	1092	7	identified	identify	VBN
cord-010027-r0tl01kq	1092	8	,	,	,
cord-010027-r0tl01kq	1092	9	24	24	CD
cord-010027-r0tl01kq	1092	10	(	(	-LRB-
cord-010027-r0tl01kq	1092	11	58.5	58.5	CD
cord-010027-r0tl01kq	1092	12	%	%	NN
cord-010027-r0tl01kq	1092	13	)	)	-RRB-
cord-010027-r0tl01kq	1092	14	underwent	undergo	VBD
cord-010027-r0tl01kq	1092	15	genetic	genetic	JJ
cord-010027-r0tl01kq	1092	16	counselling	counselling	NN
cord-010027-r0tl01kq	1092	17	/	/	SYM
cord-010027-r0tl01kq	1092	18	testing	testing	NN
cord-010027-r0tl01kq	1092	19	and	and	CC
cord-010027-r0tl01kq	1092	20	13	13	CD
cord-010027-r0tl01kq	1092	21	cases	case	NNS
cord-010027-r0tl01kq	1092	22	were	be	VBD
cord-010027-r0tl01kq	1092	23	confirmed	confirm	VBN
cord-010027-r0tl01kq	1092	24	LS	LS	NNP
cord-010027-r0tl01kq	1092	25	with	with	IN
cord-010027-r0tl01kq	1092	26	germline	germline	JJ
cord-010027-r0tl01kq	1092	27	pathogenic	pathogenic	JJ
cord-010027-r0tl01kq	1092	28	mutations	mutation	NNS
cord-010027-r0tl01kq	1092	29	in	in	IN
cord-010027-r0tl01kq	1092	30	the	the	DT
cord-010027-r0tl01kq	1092	31	MMR	MMR	NNP
cord-010027-r0tl01kq	1092	32	genes	gene	NNS
cord-010027-r0tl01kq	1092	33	.	.	.
cord-010027-r0tl01kq	1093	1	Eight	eight	CD
cord-010027-r0tl01kq	1093	2	of	of	IN
cord-010027-r0tl01kq	1093	3	these	these	DT
cord-010027-r0tl01kq	1093	4	were	be	VBD
cord-010027-r0tl01kq	1093	5	identified	identify	VBN
cord-010027-r0tl01kq	1093	6	using	use	VBG
cord-010027-r0tl01kq	1093	7	reflex	reflex	NN
cord-010027-r0tl01kq	1093	8	testing	testing	NN
cord-010027-r0tl01kq	1093	9	.	.	.
cord-010027-r0tl01kq	1094	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1094	2	:	:	:
cord-010027-r0tl01kq	1095	1	This	this	DT
cord-010027-r0tl01kq	1095	2	is	be	VBZ
cord-010027-r0tl01kq	1095	3	the	the	DT
cord-010027-r0tl01kq	1095	4	first	first	JJ
cord-010027-r0tl01kq	1095	5	UK	UK	NNP
cord-010027-r0tl01kq	1095	6	study	study	NN
cord-010027-r0tl01kq	1095	7	to	to	TO
cord-010027-r0tl01kq	1095	8	show	show	VB
cord-010027-r0tl01kq	1095	9	that	that	IN
cord-010027-r0tl01kq	1095	10	screening	screening	NN
cord-010027-r0tl01kq	1095	11	for	for	IN
cord-010027-r0tl01kq	1095	12	LS	ls	NN
cord-010027-r0tl01kq	1095	13	in	in	IN
cord-010027-r0tl01kq	1095	14	patients	patient	NNS
cord-010027-r0tl01kq	1095	15	with	with	IN
cord-010027-r0tl01kq	1095	16	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1095	17	cancer	cancer	NN
cord-010027-r0tl01kq	1095	18	under	under	IN
cord-010027-r0tl01kq	1095	19	the	the	DT
cord-010027-r0tl01kq	1095	20	age	age	NN
cord-010027-r0tl01kq	1095	21	of	of	IN
cord-010027-r0tl01kq	1095	22	60	60	CD
cord-010027-r0tl01kq	1095	23	is	be	VBZ
cord-010027-r0tl01kq	1095	24	effective	effective	JJ
cord-010027-r0tl01kq	1095	25	at	at	IN
cord-010027-r0tl01kq	1095	26	identifying	identify	VBG
cord-010027-r0tl01kq	1095	27	families	family	NNS
cord-010027-r0tl01kq	1095	28	with	with	IN
cord-010027-r0tl01kq	1095	29	LS	LS	NNP
cord-010027-r0tl01kq	1095	30	.	.	.
cord-010027-r0tl01kq	1096	1	The	the	DT
cord-010027-r0tl01kq	1096	2	testing	testing	NN
cord-010027-r0tl01kq	1096	3	protocol	protocol	NN
cord-010027-r0tl01kq	1096	4	is	be	VBZ
cord-010027-r0tl01kq	1096	5	in	in	IN
cord-010027-r0tl01kq	1096	6	line	line	NN
cord-010027-r0tl01kq	1096	7	with	with	IN
cord-010027-r0tl01kq	1096	8	the	the	DT
cord-010027-r0tl01kq	1096	9	recent	recent	JJ
cord-010027-r0tl01kq	1096	10	recommendations	recommendation	NNS
cord-010027-r0tl01kq	1096	11	.	.	.
cord-010027-r0tl01kq	1097	1	The	the	DT
cord-010027-r0tl01kq	1097	2	human	human	JJ
cord-010027-r0tl01kq	1097	3	microbiome	microbiome	NN
cord-010027-r0tl01kq	1097	4	is	be	VBZ
cord-010027-r0tl01kq	1097	5	rich	rich	JJ
cord-010027-r0tl01kq	1097	6	and	and	CC
cord-010027-r0tl01kq	1097	7	diverse	diverse	JJ
cord-010027-r0tl01kq	1097	8	,	,	,
cord-010027-r0tl01kq	1097	9	especially	especially	RB
cord-010027-r0tl01kq	1097	10	in	in	IN
cord-010027-r0tl01kq	1097	11	the	the	DT
cord-010027-r0tl01kq	1097	12	oral	oral	JJ
cord-010027-r0tl01kq	1097	13	cavity	cavity	NN
cord-010027-r0tl01kq	1097	14	and	and	CC
cord-010027-r0tl01kq	1097	15	gastro	gastro	JJ
cord-010027-r0tl01kq	1097	16	-	-	JJ
cord-010027-r0tl01kq	1097	17	intestinal	intestinal	JJ
cord-010027-r0tl01kq	1097	18	tract	tract	NN
cord-010027-r0tl01kq	1097	19	,	,	,
cord-010027-r0tl01kq	1097	20	where	where	WRB
cord-010027-r0tl01kq	1097	21	it	-PRON-	PRP
cord-010027-r0tl01kq	1097	22	has	have	VBZ
cord-010027-r0tl01kq	1097	23	been	be	VBN
cord-010027-r0tl01kq	1097	24	shown	show	VBN
cord-010027-r0tl01kq	1097	25	to	to	TO
cord-010027-r0tl01kq	1097	26	be	be	VB
cord-010027-r0tl01kq	1097	27	more	more	RBR
cord-010027-r0tl01kq	1097	28	stable	stable	JJ
cord-010027-r0tl01kq	1097	29	in	in	IN
cord-010027-r0tl01kq	1097	30	adults	adult	NNS
cord-010027-r0tl01kq	1097	31	,	,	,
cord-010027-r0tl01kq	1097	32	although	although	IN
cord-010027-r0tl01kq	1097	33	various	various	JJ
cord-010027-r0tl01kq	1097	34	factors	factor	NNS
cord-010027-r0tl01kq	1097	35	such	such	JJ
cord-010027-r0tl01kq	1097	36	as	as	IN
cord-010027-r0tl01kq	1097	37	diet	diet	NN
cord-010027-r0tl01kq	1097	38	and	and	CC
cord-010027-r0tl01kq	1097	39	antibiotics	antibiotic	NNS
cord-010027-r0tl01kq	1097	40	mays	mays	NNP
cord-010027-r0tl01kq	1097	41	influence	influence	VBP
cord-010027-r0tl01kq	1097	42	its	-PRON-	PRP$
cord-010027-r0tl01kq	1097	43	composition	composition	NN
cord-010027-r0tl01kq	1097	44	.	.	.
cord-010027-r0tl01kq	1098	1	This	this	DT
cord-010027-r0tl01kq	1098	2	pilot	pilot	NN
cord-010027-r0tl01kq	1098	3	study	study	NN
cord-010027-r0tl01kq	1098	4	aimed	aim	VBN
cord-010027-r0tl01kq	1098	5	to	to	TO
cord-010027-r0tl01kq	1098	6	examine	examine	VB
cord-010027-r0tl01kq	1098	7	and	and	CC
cord-010027-r0tl01kq	1098	8	compare	compare	VB
cord-010027-r0tl01kq	1098	9	the	the	DT
cord-010027-r0tl01kq	1098	10	oral	oral	JJ
cord-010027-r0tl01kq	1098	11	and	and	CC
cord-010027-r0tl01kq	1098	12	gut	gut	VB
cord-010027-r0tl01kq	1098	13	microbial	microbial	JJ
cord-010027-r0tl01kq	1098	14	composition	composition	NN
cord-010027-r0tl01kq	1098	15	in	in	IN
cord-010027-r0tl01kq	1098	16	four	four	CD
cord-010027-r0tl01kq	1098	17	individuals	individual	NNS
cord-010027-r0tl01kq	1098	18	using	use	VBG
cord-010027-r0tl01kq	1098	19	a	a	DT
cord-010027-r0tl01kq	1098	20	culture	culture	NN
cord-010027-r0tl01kq	1098	21	-	-	HYPH
cord-010027-r0tl01kq	1098	22	independent	independent	JJ
cord-010027-r0tl01kq	1098	23	approach	approach	NN
cord-010027-r0tl01kq	1098	24	.	.	.
cord-010027-r0tl01kq	1099	1	Methods	method	NNS
cord-010027-r0tl01kq	1099	2	:	:	:
cord-010027-r0tl01kq	1100	1	Saliva	saliva	NN
cord-010027-r0tl01kq	1100	2	and	and	CC
cord-010027-r0tl01kq	1100	3	faecal	faecal	JJ
cord-010027-r0tl01kq	1100	4	samples	sample	NNS
cord-010027-r0tl01kq	1100	5	were	be	VBD
cord-010027-r0tl01kq	1100	6	collected	collect	VBN
cord-010027-r0tl01kq	1100	7	from	from	IN
cord-010027-r0tl01kq	1100	8	volunteers	volunteer	NNS
cord-010027-r0tl01kq	1100	9	within	within	IN
cord-010027-r0tl01kq	1100	10	the	the	DT
cord-010027-r0tl01kq	1100	11	same	same	JJ
cord-010027-r0tl01kq	1100	12	day	day	NN
cord-010027-r0tl01kq	1100	13	on	on	IN
cord-010027-r0tl01kq	1100	14	two	two	CD
cord-010027-r0tl01kq	1100	15	separate	separate	JJ
cord-010027-r0tl01kq	1100	16	occasions	occasion	NNS
cord-010027-r0tl01kq	1100	17	.	.	.
cord-010027-r0tl01kq	1101	1	The	the	DT
cord-010027-r0tl01kq	1101	2	V4	V4	NNP
cord-010027-r0tl01kq	1101	3	region	region	NN
cord-010027-r0tl01kq	1101	4	of	of	IN
cord-010027-r0tl01kq	1101	5	the	the	DT
cord-010027-r0tl01kq	1101	6	16S	16S	NNP
cord-010027-r0tl01kq	1101	7	rRNA	rRNA	NNP
cord-010027-r0tl01kq	1101	8	gene	gene	NN
cord-010027-r0tl01kq	1101	9	was	be	VBD
cord-010027-r0tl01kq	1101	10	amplified	amplify	VBN
cord-010027-r0tl01kq	1101	11	in	in	IN
cord-010027-r0tl01kq	1101	12	all	all	DT
cord-010027-r0tl01kq	1101	13	samples	sample	NNS
cord-010027-r0tl01kq	1101	14	and	and	CC
cord-010027-r0tl01kq	1101	15	PCR	PCR	NNP
cord-010027-r0tl01kq	1101	16	products	product	NNS
cord-010027-r0tl01kq	1101	17	sequenced	sequence	VBN
cord-010027-r0tl01kq	1101	18	on	on	IN
cord-010027-r0tl01kq	1101	19	an	an	DT
cord-010027-r0tl01kq	1101	20	Illumina	Illumina	NNP
cord-010027-r0tl01kq	1101	21	MiSeq	MiSeq	NNP
cord-010027-r0tl01kq	1101	22	.	.	.
cord-010027-r0tl01kq	1102	1	Unique	unique	JJ
cord-010027-r0tl01kq	1102	2	barcodes	barcode	NNS
cord-010027-r0tl01kq	1102	3	were	be	VBD
cord-010027-r0tl01kq	1102	4	used	use	VBN
cord-010027-r0tl01kq	1102	5	to	to	TO
cord-010027-r0tl01kq	1102	6	sequence	sequence	VB
cord-010027-r0tl01kq	1102	7	24	24	CD
cord-010027-r0tl01kq	1102	8	multiplexed	multiplexed	JJ
cord-010027-r0tl01kq	1102	9	libraries	library	NNS
cord-010027-r0tl01kq	1102	10	together	together	RB
cord-010027-r0tl01kq	1102	11	.	.	.
cord-010027-r0tl01kq	1103	1	The	the	DT
cord-010027-r0tl01kq	1103	2	data	datum	NNS
cord-010027-r0tl01kq	1103	3	were	be	VBD
cord-010027-r0tl01kq	1103	4	analysed	analyse	VBN
cord-010027-r0tl01kq	1103	5	using	use	VBG
cord-010027-r0tl01kq	1103	6	the	the	DT
cord-010027-r0tl01kq	1103	7	Quantitative	Quantitative	NNP
cord-010027-r0tl01kq	1103	8	Insights	Insights	NNPS
cord-010027-r0tl01kq	1103	9	into	into	IN
cord-010027-r0tl01kq	1103	10	Microbial	Microbial	NNP
cord-010027-r0tl01kq	1103	11	Ecology	Ecology	NNP
cord-010027-r0tl01kq	1103	12	(	(	-LRB-
cord-010027-r0tl01kq	1103	13	QIIME	QIIME	NNP
cord-010027-r0tl01kq	1103	14	)	)	-RRB-
cord-010027-r0tl01kq	1103	15	software	software	NN
cord-010027-r0tl01kq	1103	16	.	.	.
cord-010027-r0tl01kq	1104	1	A	a	DT
cord-010027-r0tl01kq	1104	2	second	second	JJ
cord-010027-r0tl01kq	1104	3	series	series	NN
cord-010027-r0tl01kq	1104	4	of	of	IN
cord-010027-r0tl01kq	1104	5	42	42	CD
cord-010027-r0tl01kq	1104	6	samples	sample	NNS
cord-010027-r0tl01kq	1104	7	of	of	IN
cord-010027-r0tl01kq	1104	8	faeces	faece	NNS
cord-010027-r0tl01kq	1104	9	from	from	IN
cord-010027-r0tl01kq	1104	10	3	3	CD
cord-010027-r0tl01kq	1104	11	individuals	individual	NNS
cord-010027-r0tl01kq	1104	12	were	be	VBD
cord-010027-r0tl01kq	1104	13	run	run	VBN
cord-010027-r0tl01kq	1104	14	to	to	TO
cord-010027-r0tl01kq	1104	15	investigate	investigate	VB
cord-010027-r0tl01kq	1104	16	consistency	consistency	NN
cord-010027-r0tl01kq	1104	17	over	over	IN
cord-010027-r0tl01kq	1104	18	time	time	NN
cord-010027-r0tl01kq	1104	19	.	.	.
cord-010027-r0tl01kq	1105	1	Operational	operational	JJ
cord-010027-r0tl01kq	1105	2	taxonomic	taxonomic	JJ
cord-010027-r0tl01kq	1105	3	units	unit	NNS
cord-010027-r0tl01kq	1105	4	(	(	-LRB-
cord-010027-r0tl01kq	1105	5	OTUs	otu	NNS
cord-010027-r0tl01kq	1105	6	)	)	-RRB-
cord-010027-r0tl01kq	1105	7	were	be	VBD
cord-010027-r0tl01kq	1105	8	assessed	assess	VBN
cord-010027-r0tl01kq	1105	9	and	and	CC
cord-010027-r0tl01kq	1105	10	showed	show	VBD
cord-010027-r0tl01kq	1105	11	5	5	CD
cord-010027-r0tl01kq	1105	12	major	major	JJ
cord-010027-r0tl01kq	1105	13	phyla	phylum	NNS
cord-010027-r0tl01kq	1105	14	represented	represent	VBN
cord-010027-r0tl01kq	1105	15	in	in	IN
cord-010027-r0tl01kq	1105	16	the	the	DT
cord-010027-r0tl01kq	1105	17	saliva	saliva	NN
cord-010027-r0tl01kq	1105	18	samples	sample	NNS
cord-010027-r0tl01kq	1105	19	:	:	:
cord-010027-r0tl01kq	1106	1	Firmicutes	Firmicutes	NNPS
cord-010027-r0tl01kq	1106	2	,	,	,
cord-010027-r0tl01kq	1106	3	Proteobacteria	Proteobacteria	NNP
cord-010027-r0tl01kq	1106	4	,	,	,
cord-010027-r0tl01kq	1106	5	Bacteroidetes	Bacteroidetes	NNPS
cord-010027-r0tl01kq	1106	6	,	,	,
cord-010027-r0tl01kq	1106	7	Fusobacteria	Fusobacteria	NNP
cord-010027-r0tl01kq	1106	8	and	and	CC
cord-010027-r0tl01kq	1106	9	Actinobacteria	Actinobacteria	NNP
cord-010027-r0tl01kq	1106	10	.	.	.
cord-010027-r0tl01kq	1107	1	Similar	similar	JJ
cord-010027-r0tl01kq	1107	2	phyla	phylum	NNS
cord-010027-r0tl01kq	1107	3	except	except	IN
cord-010027-r0tl01kq	1107	4	forFusobacteria	forfusobacteria	NN
cord-010027-r0tl01kq	1107	5	,	,	,
cord-010027-r0tl01kq	1107	6	were	be	VBD
cord-010027-r0tl01kq	1107	7	found	find	VBN
cord-010027-r0tl01kq	1107	8	in	in	IN
cord-010027-r0tl01kq	1107	9	the	the	DT
cord-010027-r0tl01kq	1107	10	stool	stool	NN
cord-010027-r0tl01kq	1107	11	samples	sample	NNS
cord-010027-r0tl01kq	1107	12	.	.	.
cord-010027-r0tl01kq	1108	1	The	the	DT
cord-010027-r0tl01kq	1108	2	weighted	weighted	JJ
cord-010027-r0tl01kq	1108	3	Unifrac	Unifrac	NNP
cord-010027-r0tl01kq	1108	4	PCoA	PCoA	NNP
cord-010027-r0tl01kq	1108	5	analysis	analysis	NN
cord-010027-r0tl01kq	1108	6	displayed	display	VBD
cord-010027-r0tl01kq	1108	7	a	a	DT
cord-010027-r0tl01kq	1108	8	clear	clear	JJ
cord-010027-r0tl01kq	1108	9	separation	separation	NN
cord-010027-r0tl01kq	1108	10	of	of	IN
cord-010027-r0tl01kq	1108	11	the	the	DT
cord-010027-r0tl01kq	1108	12	2	2	CD
cord-010027-r0tl01kq	1108	13	sample	sample	NN
cord-010027-r0tl01kq	1108	14	groups	group	NNS
cord-010027-r0tl01kq	1108	15	,	,	,
cord-010027-r0tl01kq	1108	16	and	and	CC
cord-010027-r0tl01kq	1108	17	also	also	RB
cord-010027-r0tl01kq	1108	18	showed	show	VBD
cord-010027-r0tl01kq	1108	19	a	a	DT
cord-010027-r0tl01kq	1108	20	more	more	JJR
cord-010027-r0tl01kq	1108	21	disperse	disperse	NN
cord-010027-r0tl01kq	1108	22	bacterial	bacterial	JJ
cord-010027-r0tl01kq	1108	23	profile	profile	NN
cord-010027-r0tl01kq	1108	24	for	for	IN
cord-010027-r0tl01kq	1108	25	the	the	DT
cord-010027-r0tl01kq	1108	26	saliva	saliva	NN
cord-010027-r0tl01kq	1108	27	samples	sample	NNS
cord-010027-r0tl01kq	1108	28	,	,	,
cord-010027-r0tl01kq	1108	29	based	base	VBN
cord-010027-r0tl01kq	1108	30	on	on	IN
cord-010027-r0tl01kq	1108	31	population	population	NN
cord-010027-r0tl01kq	1108	32	sizes	size	NNS
cord-010027-r0tl01kq	1108	33	,	,	,
cord-010027-r0tl01kq	1108	34	whereas	whereas	IN
cord-010027-r0tl01kq	1108	35	rarefaction	rarefaction	NN
cord-010027-r0tl01kq	1108	36	curves	curve	NNS
cord-010027-r0tl01kq	1108	37	and	and	CC
cord-010027-r0tl01kq	1108	38	unweighted	unweighted	JJ
cord-010027-r0tl01kq	1108	39	analysis	analysis	NN
cord-010027-r0tl01kq	1108	40	indicated	indicate	VBD
cord-010027-r0tl01kq	1108	41	higher	high	JJR
cord-010027-r0tl01kq	1108	42	bacterial	bacterial	JJ
cord-010027-r0tl01kq	1108	43	diversity	diversity	NN
cord-010027-r0tl01kq	1108	44	in	in	IN
cord-010027-r0tl01kq	1108	45	the	the	DT
cord-010027-r0tl01kq	1108	46	stool	stool	NN
cord-010027-r0tl01kq	1108	47	samples	sample	NNS
cord-010027-r0tl01kq	1108	48	.	.	.
cord-010027-r0tl01kq	1109	1	Each	each	DT
cord-010027-r0tl01kq	1109	2	individual	individual	NN
cord-010027-r0tl01kq	1109	3	could	could	MD
cord-010027-r0tl01kq	1109	4	be	be	VB
cord-010027-r0tl01kq	1109	5	distinguished	distinguish	VBN
cord-010027-r0tl01kq	1109	6	either	either	CC
cord-010027-r0tl01kq	1109	7	by	by	IN
cord-010027-r0tl01kq	1109	8	oral	oral	JJ
cord-010027-r0tl01kq	1109	9	or	or	CC
cord-010027-r0tl01kq	1109	10	faecal	faecal	JJ
cord-010027-r0tl01kq	1109	11	microbiome	microbiome	NN
cord-010027-r0tl01kq	1109	12	.	.	.
cord-010027-r0tl01kq	1110	1	One	one	CD
cord-010027-r0tl01kq	1110	2	volunteer	volunteer	NN
cord-010027-r0tl01kq	1110	3	who	who	WP
cord-010027-r0tl01kq	1110	4	had	have	VBD
cord-010027-r0tl01kq	1110	5	had	have	VBN
cord-010027-r0tl01kq	1110	6	previous	previous	JJ
cord-010027-r0tl01kq	1110	7	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1110	8	to	to	IN
cord-010027-r0tl01kq	1110	9	the	the	DT
cord-010027-r0tl01kq	1110	10	mouth	mouth	NN
cord-010027-r0tl01kq	1110	11	displayed	display	VBD
cord-010027-r0tl01kq	1110	12	a	a	DT
cord-010027-r0tl01kq	1110	13	particularly	particularly	RB
cord-010027-r0tl01kq	1110	14	distinct	distinct	JJ
cord-010027-r0tl01kq	1110	15	oral	oral	JJ
cord-010027-r0tl01kq	1110	16	microbiota	microbiota	NN
cord-010027-r0tl01kq	1110	17	.	.	.
cord-010027-r0tl01kq	1111	1	The	the	DT
cord-010027-r0tl01kq	1111	2	microbial	microbial	JJ
cord-010027-r0tl01kq	1111	3	community	community	NN
cord-010027-r0tl01kq	1111	4	profiles	profile	NNS
cord-010027-r0tl01kq	1111	5	of	of	IN
cord-010027-r0tl01kq	1111	6	saliva	saliva	NN
cord-010027-r0tl01kq	1111	7	and	and	CC
cord-010027-r0tl01kq	1111	8	faecal	faecal	JJ
cord-010027-r0tl01kq	1111	9	samples	sample	NNS
cord-010027-r0tl01kq	1111	10	of	of	IN
cord-010027-r0tl01kq	1111	11	four	four	CD
cord-010027-r0tl01kq	1111	12	individuals	individual	NNS
cord-010027-r0tl01kq	1111	13	were	be	VBD
cord-010027-r0tl01kq	1111	14	found	find	VBN
cord-010027-r0tl01kq	1111	15	to	to	TO
cord-010027-r0tl01kq	1111	16	be	be	VB
cord-010027-r0tl01kq	1111	17	distinct	distinct	JJ
cord-010027-r0tl01kq	1111	18	from	from	IN
cord-010027-r0tl01kq	1111	19	each	each	DT
cord-010027-r0tl01kq	1111	20	other	other	JJ
cord-010027-r0tl01kq	1111	21	,	,	,
cord-010027-r0tl01kq	1111	22	despite	despite	IN
cord-010027-r0tl01kq	1111	23	sharing	share	VBG
cord-010027-r0tl01kq	1111	24	similar	similar	JJ
cord-010027-r0tl01kq	1111	25	phyla	phylum	NNS
cord-010027-r0tl01kq	1111	26	.	.	.
cord-010027-r0tl01kq	1112	1	Analysis	analysis	NN
cord-010027-r0tl01kq	1112	2	of	of	IN
cord-010027-r0tl01kq	1112	3	multiple	multiple	JJ
cord-010027-r0tl01kq	1112	4	samples	sample	NNS
cord-010027-r0tl01kq	1112	5	from	from	IN
cord-010027-r0tl01kq	1112	6	each	each	DT
cord-010027-r0tl01kq	1112	7	volunteer	volunteer	NN
cord-010027-r0tl01kq	1112	8	clearly	clearly	RB
cord-010027-r0tl01kq	1112	9	separated	separate	VBD
cord-010027-r0tl01kq	1112	10	each	each	DT
cord-010027-r0tl01kq	1112	11	sample	sample	NN
cord-010027-r0tl01kq	1112	12	by	by	IN
cord-010027-r0tl01kq	1112	13	volunteer	volunteer	NN
cord-010027-r0tl01kq	1112	14	and	and	CC
cord-010027-r0tl01kq	1112	15	by	by	IN
cord-010027-r0tl01kq	1112	16	sample	sample	NN
cord-010027-r0tl01kq	1112	17	type	type	NN
cord-010027-r0tl01kq	1112	18	.	.	.
cord-010027-r0tl01kq	1113	1	Are	be	VBP
cord-010027-r0tl01kq	1113	2	Current	current	JJ
cord-010027-r0tl01kq	1113	3	Automated	Automated	NNP
cord-010027-r0tl01kq	1113	4	Approaches	approach	NNS
cord-010027-r0tl01kq	1113	5	for	for	IN
cord-010027-r0tl01kq	1113	6	Determining	determine	VBG
cord-010027-r0tl01kq	1113	7	the	the	DT
cord-010027-r0tl01kq	1113	8	Phylogeny	Phylogeny	NNP
cord-010027-r0tl01kq	1113	9	of	of	IN
cord-010027-r0tl01kq	1113	10	Multiple	Multiple	NNP
cord-010027-r0tl01kq	1113	11	Deposits	deposit	NNS
cord-010027-r0tl01kq	1113	12	Capable	capable	JJ
cord-010027-r0tl01kq	1113	13	of	of	IN
cord-010027-r0tl01kq	1113	14	Interpreting	interpret	VBG
cord-010027-r0tl01kq	1113	15	the	the	DT
cord-010027-r0tl01kq	1113	16	Complexity	Complexity	NNP
cord-010027-r0tl01kq	1113	17	of	of	IN
cord-010027-r0tl01kq	1113	18	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1113	19	Evolution	evolution	NN
cord-010027-r0tl01kq	1113	20	?	?	.
cord-010027-r0tl01kq	1114	1	P	P	NNP
cord-010027-r0tl01kq	1114	2	TG	TG	NNP
cord-010027-r0tl01kq	1114	3	Palmer	Palmer	NNP
cord-010027-r0tl01kq	1114	4	;	;	:
cord-010027-r0tl01kq	1114	5	HM	HM	NNP
cord-010027-r0tl01kq	1114	6	Wood	Wood	NNP
cord-010027-r0tl01kq	1114	7	;	;	:
cord-010027-r0tl01kq	1114	8	M	M	NNP
cord-010027-r0tl01kq	1114	9	Taylor	Taylor	NNP
cord-010027-r0tl01kq	1114	10	;	;	:
cord-010027-r0tl01kq	1114	11	W	W	NNP
cord-010027-r0tl01kq	1114	12	Fateen	Fateen	NNP
cord-010027-r0tl01kq	1114	13	;	;	:
cord-010027-r0tl01kq	1114	14	IM	IM	NNP
cord-010027-r0tl01kq	1114	15	Carr	Carr	NNP
cord-010027-r0tl01kq	1114	16	;	;	:
cord-010027-r0tl01kq	1114	17	P	P	NNP
cord-010027-r0tl01kq	1114	18	Quirke	Quirke	NNP
cord-010027-r0tl01kq	1114	19	Tumour	tumour	NN
cord-010027-r0tl01kq	1114	20	heterogeneity	heterogeneity	NN
cord-010027-r0tl01kq	1114	21	is	be	VBZ
cord-010027-r0tl01kq	1114	22	central	central	JJ
cord-010027-r0tl01kq	1114	23	to	to	IN
cord-010027-r0tl01kq	1114	24	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	1114	25	resistance	resistance	NN
cord-010027-r0tl01kq	1114	26	and	and	CC
cord-010027-r0tl01kq	1114	27	disease	disease	NN
cord-010027-r0tl01kq	1114	28	progression	progression	NN
cord-010027-r0tl01kq	1114	29	in	in	IN
cord-010027-r0tl01kq	1114	30	advanced	advanced	JJ
cord-010027-r0tl01kq	1114	31	malignancy	malignancy	NN
cord-010027-r0tl01kq	1114	32	.	.	.
cord-010027-r0tl01kq	1115	1	This	this	DT
cord-010027-r0tl01kq	1115	2	heterogeneity	heterogeneity	NN
cord-010027-r0tl01kq	1115	3	arises	arise	VBZ
cord-010027-r0tl01kq	1115	4	due	due	IN
cord-010027-r0tl01kq	1115	5	to	to	IN
cord-010027-r0tl01kq	1115	6	the	the	DT
cord-010027-r0tl01kq	1115	7	evolution	evolution	NN
cord-010027-r0tl01kq	1115	8	of	of	IN
cord-010027-r0tl01kq	1115	9	clones	clone	NNS
cord-010027-r0tl01kq	1115	10	within	within	IN
cord-010027-r0tl01kq	1115	11	the	the	DT
cord-010027-r0tl01kq	1115	12	tumour	tumour	NN
cord-010027-r0tl01kq	1115	13	cell	cell	NN
cord-010027-r0tl01kq	1115	14	population	population	NN
cord-010027-r0tl01kq	1115	15	;	;	:
cord-010027-r0tl01kq	1115	16	the	the	DT
cord-010027-r0tl01kq	1115	17	advent	advent	NN
cord-010027-r0tl01kq	1115	18	of	of	IN
cord-010027-r0tl01kq	1115	19	high	high	JJ
cord-010027-r0tl01kq	1115	20	throughput	throughput	NN
cord-010027-r0tl01kq	1115	21	sequencing	sequencing	NN
cord-010027-r0tl01kq	1115	22	has	have	VBZ
cord-010027-r0tl01kq	1115	23	allowed	allow	VBN
cord-010027-r0tl01kq	1115	24	the	the	DT
cord-010027-r0tl01kq	1115	25	detection	detection	NN
cord-010027-r0tl01kq	1115	26	of	of	IN
cord-010027-r0tl01kq	1115	27	different	different	JJ
cord-010027-r0tl01kq	1115	28	tumour	tumour	NN
cord-010027-r0tl01kq	1115	29	cell	cell	NN
cord-010027-r0tl01kq	1115	30	clones	clone	NNS
cord-010027-r0tl01kq	1115	31	within	within	IN
cord-010027-r0tl01kq	1115	32	and	and	CC
cord-010027-r0tl01kq	1115	33	between	between	IN
cord-010027-r0tl01kq	1115	34	primary	primary	JJ
cord-010027-r0tl01kq	1115	35	tumours	tumour	NNS
cord-010027-r0tl01kq	1115	36	and	and	CC
cord-010027-r0tl01kq	1115	37	their	-PRON-	PRP$
cord-010027-r0tl01kq	1115	38	metastases	metastasis	NNS
cord-010027-r0tl01kq	1115	39	,	,	,
cord-010027-r0tl01kq	1115	40	potentially	potentially	RB
cord-010027-r0tl01kq	1115	41	allowing	allow	VBG
cord-010027-r0tl01kq	1115	42	mapping	mapping	NN
cord-010027-r0tl01kq	1115	43	of	of	IN
cord-010027-r0tl01kq	1115	44	tumour	tumour	NN
cord-010027-r0tl01kq	1115	45	evolution	evolution	NN
cord-010027-r0tl01kq	1115	46	.	.	.
cord-010027-r0tl01kq	1116	1	Several	several	JJ
cord-010027-r0tl01kq	1116	2	,	,	,
cord-010027-r0tl01kq	1116	3	automated	automate	VBN
cord-010027-r0tl01kq	1116	4	bioinformatic	bioinformatic	JJ
cord-010027-r0tl01kq	1116	5	approaches	approach	NNS
cord-010027-r0tl01kq	1116	6	have	have	VBP
cord-010027-r0tl01kq	1116	7	been	be	VBN
cord-010027-r0tl01kq	1116	8	devised	devise	VBN
cord-010027-r0tl01kq	1116	9	for	for	IN
cord-010027-r0tl01kq	1116	10	determining	determine	VBG
cord-010027-r0tl01kq	1116	11	tumour	tumour	NN
cord-010027-r0tl01kq	1116	12	phylogeny	phylogeny	NN
cord-010027-r0tl01kq	1116	13	from	from	IN
cord-010027-r0tl01kq	1116	14	changes	change	NNS
cord-010027-r0tl01kq	1116	15	in	in	IN
cord-010027-r0tl01kq	1116	16	genomic	genomic	JJ
cord-010027-r0tl01kq	1116	17	copy	copy	NN
cord-010027-r0tl01kq	1116	18	number	number	NN
cord-010027-r0tl01kq	1116	19	(	(	-LRB-
cord-010027-r0tl01kq	1116	20	CN	CN	NNP
cord-010027-r0tl01kq	1116	21	)	)	-RRB-
cord-010027-r0tl01kq	1116	22	;	;	:
cord-010027-r0tl01kq	1116	23	either	either	CC
cord-010027-r0tl01kq	1116	24	by	by	IN
cord-010027-r0tl01kq	1116	25	the	the	DT
cord-010027-r0tl01kq	1116	26	overall	overall	JJ
cord-010027-r0tl01kq	1116	27	similarity	similarity	NN
cord-010027-r0tl01kq	1116	28	of	of	IN
cord-010027-r0tl01kq	1116	29	genomic	genomic	JJ
cord-010027-r0tl01kq	1116	30	changes	change	NNS
cord-010027-r0tl01kq	1116	31	between	between	IN
cord-010027-r0tl01kq	1116	32	tumour	tumour	NN
cord-010027-r0tl01kq	1116	33	deposits	deposit	NNS
cord-010027-r0tl01kq	1116	34	or	or	CC
cord-010027-r0tl01kq	1116	35	by	by	IN
cord-010027-r0tl01kq	1116	36	examining	examine	VBG
cord-010027-r0tl01kq	1116	37	the	the	DT
cord-010027-r0tl01kq	1116	38	occurrence	occurrence	NN
cord-010027-r0tl01kq	1116	39	of	of	IN
cord-010027-r0tl01kq	1116	40	shared	share	VBN
cord-010027-r0tl01kq	1116	41	breakpoints	breakpoint	NNS
cord-010027-r0tl01kq	1116	42	.	.	.
cord-010027-r0tl01kq	1117	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1117	2	have	have	VBP
cord-010027-r0tl01kq	1117	3	compared	compare	VBN
cord-010027-r0tl01kq	1117	4	these	these	DT
cord-010027-r0tl01kq	1117	5	automated	automate	VBN
cord-010027-r0tl01kq	1117	6	approaches	approach	NNS
cord-010027-r0tl01kq	1117	7	with	with	IN
cord-010027-r0tl01kq	1117	8	a	a	DT
cord-010027-r0tl01kq	1117	9	manual	manual	JJ
cord-010027-r0tl01kq	1117	10	determination	determination	NN
cord-010027-r0tl01kq	1117	11	of	of	IN
cord-010027-r0tl01kq	1117	12	phylogeny	phylogeny	NN
cord-010027-r0tl01kq	1117	13	based	base	VBN
cord-010027-r0tl01kq	1117	14	upon	upon	IN
cord-010027-r0tl01kq	1117	15	shared	share	VBN
cord-010027-r0tl01kq	1117	16	breakpoints	breakpoint	NNS
cord-010027-r0tl01kq	1117	17	identified	identify	VBN
cord-010027-r0tl01kq	1117	18	from	from	IN
cord-010027-r0tl01kq	1117	19	four	four	CD
cord-010027-r0tl01kq	1117	20	cases	case	NNS
cord-010027-r0tl01kq	1117	21	of	of	IN
cord-010027-r0tl01kq	1117	22	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1117	23	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1117	24	cancer	cancer	NN
cord-010027-r0tl01kq	1117	25	consisting	consist	VBG
cord-010027-r0tl01kq	1117	26	of	of	IN
cord-010027-r0tl01kq	1117	27	between	between	IN
cord-010027-r0tl01kq	1117	28	6	6	CD
cord-010027-r0tl01kq	1117	29	and	and	CC
cord-010027-r0tl01kq	1117	30	53	53	CD
cord-010027-r0tl01kq	1117	31	deposits	deposit	NNS
cord-010027-r0tl01kq	1117	32	.	.	.
cord-010027-r0tl01kq	1118	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1118	2	illustrate	illustrate	VBP
cord-010027-r0tl01kq	1118	3	several	several	JJ
cord-010027-r0tl01kq	1118	4	recurrent	recurrent	JJ
cord-010027-r0tl01kq	1118	5	issues	issue	NNS
cord-010027-r0tl01kq	1118	6	identified	identify	VBN
cord-010027-r0tl01kq	1118	7	with	with	IN
cord-010027-r0tl01kq	1118	8	the	the	DT
cord-010027-r0tl01kq	1118	9	use	use	NN
cord-010027-r0tl01kq	1118	10	of	of	IN
cord-010027-r0tl01kq	1118	11	automated	automate	VBN
cord-010027-r0tl01kq	1118	12	systems	system	NNS
cord-010027-r0tl01kq	1118	13	for	for	IN
cord-010027-r0tl01kq	1118	14	the	the	DT
cord-010027-r0tl01kq	1118	15	determination	determination	NN
cord-010027-r0tl01kq	1118	16	of	of	IN
cord-010027-r0tl01kq	1118	17	tumour	tumour	NN
cord-010027-r0tl01kq	1118	18	phylogeny	phylogeny	NN
cord-010027-r0tl01kq	1118	19	associated	associate	VBN
cord-010027-r0tl01kq	1118	20	with	with	IN
cord-010027-r0tl01kq	1118	21	an	an	DT
cord-010027-r0tl01kq	1118	22	inability	inability	NN
cord-010027-r0tl01kq	1118	23	to	to	TO
cord-010027-r0tl01kq	1118	24	correctly	correctly	RB
cord-010027-r0tl01kq	1118	25	identify	identify	VB
cord-010027-r0tl01kq	1118	26	and	and	CC
cord-010027-r0tl01kq	1118	27	interpret	interpret	VB
cord-010027-r0tl01kq	1118	28	changes	change	NNS
cord-010027-r0tl01kq	1118	29	in	in	IN
cord-010027-r0tl01kq	1118	30	ploidy	ploidy	NN
cord-010027-r0tl01kq	1118	31	,	,	,
cord-010027-r0tl01kq	1118	32	an	an	DT
cord-010027-r0tl01kq	1118	33	inability	inability	NN
cord-010027-r0tl01kq	1118	34	to	to	TO
cord-010027-r0tl01kq	1118	35	identify	identify	VB
cord-010027-r0tl01kq	1118	36	heterogeneity	heterogeneity	NN
cord-010027-r0tl01kq	1118	37	within	within	IN
cord-010027-r0tl01kq	1118	38	tumour	tumour	NN
cord-010027-r0tl01kq	1118	39	deposits	deposit	NNS
cord-010027-r0tl01kq	1118	40	,	,	,
cord-010027-r0tl01kq	1118	41	the	the	DT
cord-010027-r0tl01kq	1118	42	masking	masking	NN
cord-010027-r0tl01kq	1118	43	of	of	IN
cord-010027-r0tl01kq	1118	44	smaller	small	JJR
cord-010027-r0tl01kq	1118	45	events	event	NNS
cord-010027-r0tl01kq	1118	46	by	by	IN
cord-010027-r0tl01kq	1118	47	larger	large	JJR
cord-010027-r0tl01kq	1118	48	ones	one	NNS
cord-010027-r0tl01kq	1118	49	,	,	,
cord-010027-r0tl01kq	1118	50	overinterpretation	overinterpretation	NN
cord-010027-r0tl01kq	1118	51	of	of	IN
cord-010027-r0tl01kq	1118	52	convergent	convergent	NN
cord-010027-r0tl01kq	1118	53	,	,	,
cord-010027-r0tl01kq	1118	54	but	but	CC
cord-010027-r0tl01kq	1118	55	unrelated	unrelated	JJ
cord-010027-r0tl01kq	1118	56	events	event	NNS
cord-010027-r0tl01kq	1118	57	,	,	,
cord-010027-r0tl01kq	1118	58	over	over	IN
cord-010027-r0tl01kq	1118	59	calling	call	VBG
cord-010027-r0tl01kq	1118	60	sequencing	sequencing	NN
cord-010027-r0tl01kq	1118	61	artefacts	artefact	NNS
cord-010027-r0tl01kq	1118	62	as	as	IN
cord-010027-r0tl01kq	1118	63	changes	change	NNS
cord-010027-r0tl01kq	1118	64	in	in	IN
cord-010027-r0tl01kq	1118	65	CN	CN	NNP
cord-010027-r0tl01kq	1118	66	,	,	,
cord-010027-r0tl01kq	1118	67	and	and	CC
cord-010027-r0tl01kq	1118	68	non	non	JJ
cord-010027-r0tl01kq	1118	69	-	-	JJ
cord-010027-r0tl01kq	1118	70	calling	calling	JJ
cord-010027-r0tl01kq	1118	71	of	of	IN
cord-010027-r0tl01kq	1118	72	genuine	genuine	JJ
cord-010027-r0tl01kq	1118	73	CN	cn	NN
cord-010027-r0tl01kq	1118	74	changes	change	NNS
cord-010027-r0tl01kq	1118	75	due	due	JJ
cord-010027-r0tl01kq	1118	76	to	to	IN
cord-010027-r0tl01kq	1118	77	low	low	JJ
cord-010027-r0tl01kq	1118	78	tumour	tumour	NN
cord-010027-r0tl01kq	1118	79	cell	cell	NN
cord-010027-r0tl01kq	1118	80	content	content	NN
cord-010027-r0tl01kq	1118	81	or	or	CC
cord-010027-r0tl01kq	1118	82	low	low	JJ
cord-010027-r0tl01kq	1118	83	sequencing	sequencing	NN
cord-010027-r0tl01kq	1118	84	depth	depth	NN
cord-010027-r0tl01kq	1118	85	.	.	.
cord-010027-r0tl01kq	1119	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1119	2	conclude	conclude	VBP
cord-010027-r0tl01kq	1119	3	that	that	IN
cord-010027-r0tl01kq	1119	4	manual	manual	JJ
cord-010027-r0tl01kq	1119	5	interpretation	interpretation	NN
cord-010027-r0tl01kq	1119	6	of	of	IN
cord-010027-r0tl01kq	1119	7	bioinformatics	bioinformatics	NN
cord-010027-r0tl01kq	1119	8	data	data	NN
cord-010027-r0tl01kq	1119	9	is	be	VBZ
cord-010027-r0tl01kq	1119	10	still	still	RB
cord-010027-r0tl01kq	1119	11	required	require	VBN
cord-010027-r0tl01kq	1119	12	to	to	TO
cord-010027-r0tl01kq	1119	13	determine	determine	VB
cord-010027-r0tl01kq	1119	14	the	the	DT
cord-010027-r0tl01kq	1119	15	phylogeny	phylogeny	NN
cord-010027-r0tl01kq	1119	16	of	of	IN
cord-010027-r0tl01kq	1119	17	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1119	18	cancer	cancer	NN
cord-010027-r0tl01kq	1119	19	within	within	IN
cord-010027-r0tl01kq	1119	20	an	an	DT
cord-010027-r0tl01kq	1119	21	individual	individual	NN
cord-010027-r0tl01kq	1119	22	.	.	.
cord-010027-r0tl01kq	1120	1	Results	result	NNS
cord-010027-r0tl01kq	1120	2	:	:	:
cord-010027-r0tl01kq	1121	1	Levels	level	NNS
cord-010027-r0tl01kq	1121	2	of	of	IN
cord-010027-r0tl01kq	1121	3	agreement	agreement	NN
cord-010027-r0tl01kq	1121	4	between	between	IN
cord-010027-r0tl01kq	1121	5	each	each	DT
cord-010027-r0tl01kq	1121	6	sample	sample	NN
cord-010027-r0tl01kq	1121	7	size	size	NN
cord-010027-r0tl01kq	1121	8	and	and	CC
cord-010027-r0tl01kq	1121	9	the	the	DT
cord-010027-r0tl01kq	1121	10	'	'	``
cord-010027-r0tl01kq	1121	11	gold	gold	NN
cord-010027-r0tl01kq	1121	12	standard	standard	NN
cord-010027-r0tl01kq	1121	13	'	'	''
cord-010027-r0tl01kq	1121	14	were	be	VBD
cord-010027-r0tl01kq	1121	15	evaluated	evaluate	VBN
cord-010027-r0tl01kq	1121	16	using	use	VBG
cord-010027-r0tl01kq	1121	17	Bland	Bland	NNP
cord-010027-r0tl01kq	1121	18	-	-	HYPH
cord-010027-r0tl01kq	1121	19	Altman	Altman	NNP
cord-010027-r0tl01kq	1121	20	plots	plot	NNS
cord-010027-r0tl01kq	1121	21	.	.	.
cord-010027-r0tl01kq	1122	1	7	7	CD
cord-010027-r0tl01kq	1122	2	separate	separate	JJ
cord-010027-r0tl01kq	1122	3	pairwise	pairwise	JJ
cord-010027-r0tl01kq	1122	4	comparisons	comparison	NNS
cord-010027-r0tl01kq	1122	5	were	be	VBD
cord-010027-r0tl01kq	1122	6	performed	perform	VBN
cord-010027-r0tl01kq	1122	7	.	.	.
cord-010027-r0tl01kq	1123	1	Some	some	DT
cord-010027-r0tl01kq	1123	2	small	small	JJ
cord-010027-r0tl01kq	1123	3	sample	sample	NN
cord-010027-r0tl01kq	1123	4	sizes	size	NNS
cord-010027-r0tl01kq	1123	5	were	be	VBD
cord-010027-r0tl01kq	1123	6	shown	show	VBN
cord-010027-r0tl01kq	1123	7	to	to	TO
cord-010027-r0tl01kq	1123	8	have	have	VB
cord-010027-r0tl01kq	1123	9	small	small	JJ
cord-010027-r0tl01kq	1123	10	mean	mean	VB
cord-010027-r0tl01kq	1123	11	difference	difference	NN
cord-010027-r0tl01kq	1123	12	and	and	CC
cord-010027-r0tl01kq	1123	13	narrow	narrow	JJ
cord-010027-r0tl01kq	1123	14	limit	limit	NN
cord-010027-r0tl01kq	1123	15	of	of	IN
cord-010027-r0tl01kq	1123	16	agreement	agreement	NN
cord-010027-r0tl01kq	1123	17	.	.	.
cord-010027-r0tl01kq	1124	1	The	the	DT
cord-010027-r0tl01kq	1124	2	Ki-67	Ki-67	NNPS
cord-010027-r0tl01kq	1124	3	PIs	pi	NNS
cord-010027-r0tl01kq	1124	4	were	be	VBD
cord-010027-r0tl01kq	1124	5	then	then	RB
cord-010027-r0tl01kq	1124	6	translated	translate	VBN
cord-010027-r0tl01kq	1124	7	into	into	IN
cord-010027-r0tl01kq	1124	8	grades	grade	NNS
cord-010027-r0tl01kq	1124	9	and	and	CC
cord-010027-r0tl01kq	1124	10	similar	similar	JJ
cord-010027-r0tl01kq	1124	11	comparisons	comparison	NNS
cord-010027-r0tl01kq	1124	12	were	be	VBD
cord-010027-r0tl01kq	1124	13	performed	perform	VBN
cord-010027-r0tl01kq	1124	14	by	by	IN
cord-010027-r0tl01kq	1124	15	calculating	calculate	VBG
cord-010027-r0tl01kq	1124	16	the	the	DT
cord-010027-r0tl01kq	1124	17	kappa	kappa	NN
cord-010027-r0tl01kq	1124	18	score	score	NN
cord-010027-r0tl01kq	1124	19	for	for	IN
cord-010027-r0tl01kq	1124	20	categorical	categorical	JJ
cord-010027-r0tl01kq	1124	21	variables	variable	NNS
cord-010027-r0tl01kq	1124	22	.	.	.
cord-010027-r0tl01kq	1125	1	Additionally	additionally	RB
cord-010027-r0tl01kq	1125	2	,	,	,
cord-010027-r0tl01kq	1125	3	the	the	DT
cord-010027-r0tl01kq	1125	4	interobserver	interobserver	NN
cord-010027-r0tl01kq	1125	5	variation	variation	NN
cord-010027-r0tl01kq	1125	6	between	between	IN
cord-010027-r0tl01kq	1125	7	the	the	DT
cord-010027-r0tl01kq	1125	8	two	two	CD
cord-010027-r0tl01kq	1125	9	independent	independent	JJ
cord-010027-r0tl01kq	1125	10	researchers	researcher	NNS
cord-010027-r0tl01kq	1125	11	were	be	VBD
cord-010027-r0tl01kq	1125	12	calculated	calculate	VBN
cord-010027-r0tl01kq	1125	13	.	.	.
cord-010027-r0tl01kq	1126	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1126	2	:	:	:
cord-010027-r0tl01kq	1127	1	Smaller	small	JJR
cord-010027-r0tl01kq	1127	2	sample	sample	NN
cord-010027-r0tl01kq	1127	3	sizes	size	NNS
cord-010027-r0tl01kq	1127	4	(	(	-LRB-
cord-010027-r0tl01kq	1127	5	below	below	IN
cord-010027-r0tl01kq	1127	6	1000	1000	CD
cord-010027-r0tl01kq	1127	7	)	)	-RRB-
cord-010027-r0tl01kq	1127	8	tend	tend	VBP
cord-010027-r0tl01kq	1127	9	to	to	TO
cord-010027-r0tl01kq	1127	10	overestimate	overestimate	VB
cord-010027-r0tl01kq	1127	11	the	the	DT
cord-010027-r0tl01kq	1127	12	Ki-67	Ki-67	NNP
cord-010027-r0tl01kq	1127	13	PIs	pi	NNS
cord-010027-r0tl01kq	1127	14	,	,	,
cord-010027-r0tl01kq	1127	15	possibly	possibly	RB
cord-010027-r0tl01kq	1127	16	due	due	IN
cord-010027-r0tl01kq	1127	17	to	to	IN
cord-010027-r0tl01kq	1127	18	the	the	DT
cord-010027-r0tl01kq	1127	19	effect	effect	NN
cord-010027-r0tl01kq	1127	20	of	of	IN
cord-010027-r0tl01kq	1127	21	concentric	concentric	JJ
cord-010027-r0tl01kq	1127	22	counting	counting	NN
cord-010027-r0tl01kq	1127	23	starting	start	VBG
cord-010027-r0tl01kq	1127	24	from	from	IN
cord-010027-r0tl01kq	1127	25	the	the	DT
cord-010027-r0tl01kq	1127	26	center	center	NN
cord-010027-r0tl01kq	1127	27	of	of	IN
cord-010027-r0tl01kq	1127	28	the	the	DT
cord-010027-r0tl01kq	1127	29	hotspot	hotspot	NN
cord-010027-r0tl01kq	1127	30	.	.	.
cord-010027-r0tl01kq	1128	1	However	however	RB
cord-010027-r0tl01kq	1128	2	,	,	,
cord-010027-r0tl01kq	1128	3	the	the	DT
cord-010027-r0tl01kq	1128	4	Ki-67	Ki-67	NNP
cord-010027-r0tl01kq	1128	5	PIs	pi	NNS
cord-010027-r0tl01kq	1128	6	do	do	VBP
cord-010027-r0tl01kq	1128	7	start	start	VB
cord-010027-r0tl01kq	1128	8	to	to	TO
cord-010027-r0tl01kq	1128	9	stabilise	stabilise	VB
cord-010027-r0tl01kq	1128	10	closer	close	RBR
cord-010027-r0tl01kq	1128	11	to	to	IN
cord-010027-r0tl01kq	1128	12	2000	2000	CD
cord-010027-r0tl01kq	1128	13	(	(	-LRB-
cord-010027-r0tl01kq	1128	14	e.g.	e.g.	RB
cord-010027-r0tl01kq	1128	15	1500	1500	CD
cord-010027-r0tl01kq	1128	16	)	)	-RRB-
cord-010027-r0tl01kq	1128	17	.	.	.
cord-010027-r0tl01kq	1129	1	The	the	DT
cord-010027-r0tl01kq	1129	2	interpretation	interpretation	NN
cord-010027-r0tl01kq	1129	3	of	of	IN
cord-010027-r0tl01kq	1129	4	whether	whether	IN
cord-010027-r0tl01kq	1129	5	a	a	DT
cord-010027-r0tl01kq	1129	6	lower	low	JJR
cord-010027-r0tl01kq	1129	7	sample	sample	NN
cord-010027-r0tl01kq	1129	8	size	size	NN
cord-010027-r0tl01kq	1129	9	can	can	MD
cord-010027-r0tl01kq	1129	10	replace	replace	VB
cord-010027-r0tl01kq	1129	11	the	the	DT
cord-010027-r0tl01kq	1129	12	current	current	JJ
cord-010027-r0tl01kq	1129	13	standard	standard	NN
cord-010027-r0tl01kq	1129	14	would	would	MD
cord-010027-r0tl01kq	1129	15	be	be	VB
cord-010027-r0tl01kq	1129	16	a	a	DT
cord-010027-r0tl01kq	1129	17	subjective	subjective	JJ
cord-010027-r0tl01kq	1129	18	decision	decision	NN
cord-010027-r0tl01kq	1129	19	,	,	,
cord-010027-r0tl01kq	1129	20	but	but	CC
cord-010027-r0tl01kq	1129	21	the	the	DT
cord-010027-r0tl01kq	1129	22	kappa	kappa	NN
cord-010027-r0tl01kq	1129	23	score	score	NN
cord-010027-r0tl01kq	1129	24	gives	give	VBZ
cord-010027-r0tl01kq	1129	25	a	a	DT
cord-010027-r0tl01kq	1129	26	rough	rough	JJ
cord-010027-r0tl01kq	1129	27	idea	idea	NN
cord-010027-r0tl01kq	1129	28	of	of	IN
cord-010027-r0tl01kq	1129	29	how	how	WRB
cord-010027-r0tl01kq	1129	30	much	much	JJ
cord-010027-r0tl01kq	1129	31	it	-PRON-	PRP
cord-010027-r0tl01kq	1129	32	affects	affect	VBZ
cord-010027-r0tl01kq	1129	33	the	the	DT
cord-010027-r0tl01kq	1129	34	clinical	clinical	JJ
cord-010027-r0tl01kq	1129	35	grading	grading	NN
cord-010027-r0tl01kq	1129	36	.	.	.
cord-010027-r0tl01kq	1130	1	Updated	update	VBN
cord-010027-r0tl01kq	1130	2	data	datum	NNS
cord-010027-r0tl01kq	1130	3	will	will	MD
cord-010027-r0tl01kq	1130	4	be	be	VB
cord-010027-r0tl01kq	1130	5	presented	present	VBN
cord-010027-r0tl01kq	1130	6	.	.	.
cord-010027-r0tl01kq	1131	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1131	2	of	of	IN
cord-010027-r0tl01kq	1131	3	the	the	DT
cord-010027-r0tl01kq	1131	4	Study	study	NN
cord-010027-r0tl01kq	1131	5	:	:	:
cord-010027-r0tl01kq	1131	6	Targeting	target	VBG
cord-010027-r0tl01kq	1131	7	the	the	DT
cord-010027-r0tl01kq	1131	8	stem	stem	NN
cord-010027-r0tl01kq	1131	9	cell	cell	NN
cord-010027-r0tl01kq	1131	10	properties	property	NNS
cord-010027-r0tl01kq	1131	11	of	of	IN
cord-010027-r0tl01kq	1131	12	tumor	tumor	NN
cord-010027-r0tl01kq	1131	13	-	-	HYPH
cord-010027-r0tl01kq	1131	14	initiating	initiate	VBG
cord-010027-r0tl01kq	1131	15	cells	cell	NNS
cord-010027-r0tl01kq	1131	16	is	be	VBZ
cord-010027-r0tl01kq	1131	17	an	an	DT
cord-010027-r0tl01kq	1131	18	avenue	avenue	NN
cord-010027-r0tl01kq	1131	19	through	through	IN
cord-010027-r0tl01kq	1131	20	which	which	WDT
cord-010027-r0tl01kq	1131	21	cancer	cancer	NN
cord-010027-r0tl01kq	1131	22	treatment	treatment	NN
cord-010027-r0tl01kq	1131	23	may	may	MD
cord-010027-r0tl01kq	1131	24	be	be	VB
cord-010027-r0tl01kq	1131	25	improved	improve	VBN
cord-010027-r0tl01kq	1131	26	.	.	.
cord-010027-r0tl01kq	1132	1	Before	before	IN
cord-010027-r0tl01kq	1132	2	this	this	DT
cord-010027-r0tl01kq	1132	3	can	can	MD
cord-010027-r0tl01kq	1132	4	be	be	VB
cord-010027-r0tl01kq	1132	5	achieved	achieve	VBN
cord-010027-r0tl01kq	1132	6	,	,	,
cord-010027-r0tl01kq	1132	7	so	so	RB
cord-010027-r0tl01kq	1132	8	-	-	HYPH
cord-010027-r0tl01kq	1132	9	called	call	VBN
cord-010027-r0tl01kq	1132	10	cancer	cancer	NN
cord-010027-r0tl01kq	1132	11	stem	stem	NN
cord-010027-r0tl01kq	1132	12	cell	cell	NN
cord-010027-r0tl01kq	1132	13	(	(	-LRB-
cord-010027-r0tl01kq	1132	14	CSC	CSC	NNP
cord-010027-r0tl01kq	1132	15	)	)	-RRB-
cord-010027-r0tl01kq	1132	16	models	model	NNS
cord-010027-r0tl01kq	1132	17	must	must	MD
cord-010027-r0tl01kq	1132	18	be	be	VB
cord-010027-r0tl01kq	1132	19	developed	develop	VBN
cord-010027-r0tl01kq	1132	20	and	and	CC
cord-010027-r0tl01kq	1132	21	characterized	characterize	VBN
cord-010027-r0tl01kq	1132	22	in	in	IN
cord-010027-r0tl01kq	1132	23	specific	specific	JJ
cord-010027-r0tl01kq	1132	24	malignancies	malignancy	NNS
cord-010027-r0tl01kq	1132	25	.	.	.
cord-010027-r0tl01kq	1133	1	Methods	method	NNS
cord-010027-r0tl01kq	1133	2	:	:	:
cord-010027-r0tl01kq	1133	3	In	in	IN
cord-010027-r0tl01kq	1133	4	this	this	DT
cord-010027-r0tl01kq	1133	5	study	study	NN
cord-010027-r0tl01kq	1133	6	,	,	,
cord-010027-r0tl01kq	1133	7	holoclone	holoclone	NNP
cord-010027-r0tl01kq	1133	8	formation	formation	NN
cord-010027-r0tl01kq	1133	9	assays	assay	NNS
cord-010027-r0tl01kq	1133	10	were	be	VBD
cord-010027-r0tl01kq	1133	11	used	use	VBN
cord-010027-r0tl01kq	1133	12	to	to	TO
cord-010027-r0tl01kq	1133	13	characterize	characterize	VB
cord-010027-r0tl01kq	1133	14	stem	stem	NN
cord-010027-r0tl01kq	1133	15	-	-	HYPH
cord-010027-r0tl01kq	1133	16	like	like	JJ
cord-010027-r0tl01kq	1133	17	molecular	molecular	JJ
cord-010027-r0tl01kq	1133	18	signatures	signature	NNS
cord-010027-r0tl01kq	1133	19	for	for	IN
cord-010027-r0tl01kq	1133	20	prostate	prostate	NN
cord-010027-r0tl01kq	1133	21	cancer	cancer	NN
cord-010027-r0tl01kq	1133	22	(	(	-LRB-
cord-010027-r0tl01kq	1133	23	PCa	pca	NN
cord-010027-r0tl01kq	1133	24	)	)	-RRB-
cord-010027-r0tl01kq	1133	25	cells	cell	NNS
cord-010027-r0tl01kq	1133	26	.	.	.
cord-010027-r0tl01kq	1134	1	Summary	summary	NN
cord-010027-r0tl01kq	1134	2	of	of	IN
cord-010027-r0tl01kq	1134	3	Results	result	NNS
cord-010027-r0tl01kq	1134	4	:	:	:
cord-010027-r0tl01kq	1135	1	LNCaP	LNCaP	NNP
cord-010027-r0tl01kq	1135	2	and	and	CC
cord-010027-r0tl01kq	1135	3	PC3	PC3	NNP
cord-010027-r0tl01kq	1135	4	parent	parent	NN
cord-010027-r0tl01kq	1135	5	cells	cell	NNS
cord-010027-r0tl01kq	1135	6	were	be	VBD
cord-010027-r0tl01kq	1135	7	capable	capable	JJ
cord-010027-r0tl01kq	1135	8	of	of	IN
cord-010027-r0tl01kq	1135	9	responding	respond	VBG
cord-010027-r0tl01kq	1135	10	to	to	TO
cord-010027-r0tl01kq	1135	11	stem	stem	VB
cord-010027-r0tl01kq	1135	12	cell	cell	NN
cord-010027-r0tl01kq	1135	13	differentiation	differentiation	NN
cord-010027-r0tl01kq	1135	14	morphogen	morphogen	IN
cord-010027-r0tl01kq	1135	15	retinoic	retinoic	JJ
cord-010027-r0tl01kq	1135	16	acid	acid	NN
cord-010027-r0tl01kq	1135	17	(	(	-LRB-
cord-010027-r0tl01kq	1135	18	RA	RA	NNP
cord-010027-r0tl01kq	1135	19	)	)	-RRB-
cord-010027-r0tl01kq	1135	20	,	,	,
cord-010027-r0tl01kq	1135	21	suggesting	suggest	VBG
cord-010027-r0tl01kq	1135	22	the	the	DT
cord-010027-r0tl01kq	1135	23	presence	presence	NN
cord-010027-r0tl01kq	1135	24	of	of	IN
cord-010027-r0tl01kq	1135	25	inherent	inherent	JJ
cord-010027-r0tl01kq	1135	26	stemlike	stemlike	NN
cord-010027-r0tl01kq	1135	27	properties	property	NNS
cord-010027-r0tl01kq	1135	28	.	.	.
cord-010027-r0tl01kq	1136	1	LNCaP	lncap	NN
cord-010027-r0tl01kq	1136	2	cells	cell	NNS
cord-010027-r0tl01kq	1136	3	,	,	,
cord-010027-r0tl01kq	1136	4	which	which	WDT
cord-010027-r0tl01kq	1136	5	represent	represent	VBP
cord-010027-r0tl01kq	1136	6	early	early	RB
cord-010027-r0tl01kq	1136	7	,	,	,
cord-010027-r0tl01kq	1136	8	androgen	androgen	NN
cord-010027-r0tl01kq	1136	9	-	-	HYPH
cord-010027-r0tl01kq	1136	10	responsive	responsive	JJ
cord-010027-r0tl01kq	1136	11	disease	disease	NN
cord-010027-r0tl01kq	1136	12	,	,	,
cord-010027-r0tl01kq	1136	13	formed	form	VBD
cord-010027-r0tl01kq	1136	14	holoclones	holoclone	NNS
cord-010027-r0tl01kq	1136	15	after	after	IN
cord-010027-r0tl01kq	1136	16	twenty	twenty	CD
cord-010027-r0tl01kq	1136	17	six	six	CD
cord-010027-r0tl01kq	1136	18	days	day	NNS
cord-010027-r0tl01kq	1136	19	.	.	.
cord-010027-r0tl01kq	1137	1	PC3	PC3	NNP
cord-010027-r0tl01kq	1137	2	cells	cell	NNS
cord-010027-r0tl01kq	1137	3	,	,	,
cord-010027-r0tl01kq	1137	4	which	which	WDT
cord-010027-r0tl01kq	1137	5	represent	represent	VBP
cord-010027-r0tl01kq	1137	6	advanced	advanced	JJ
cord-010027-r0tl01kq	1137	7	,	,	,
cord-010027-r0tl01kq	1137	8	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1137	9	,	,	,
cord-010027-r0tl01kq	1137	10	castrationresistant	castrationresistant	JJ
cord-010027-r0tl01kq	1137	11	disease	disease	NN
cord-010027-r0tl01kq	1137	12	,	,	,
cord-010027-r0tl01kq	1137	13	formed	form	VBD
cord-010027-r0tl01kq	1137	14	holoclones	holoclone	NNS
cord-010027-r0tl01kq	1137	15	after	after	IN
cord-010027-r0tl01kq	1137	16	only	only	RB
cord-010027-r0tl01kq	1137	17	six	six	CD
cord-010027-r0tl01kq	1137	18	days	day	NNS
cord-010027-r0tl01kq	1137	19	.	.	.
cord-010027-r0tl01kq	1138	1	Holoclones	holoclone	NNS
cord-010027-r0tl01kq	1138	2	displayed	display	VBD
cord-010027-r0tl01kq	1138	3	decreased	decrease	VBN
cord-010027-r0tl01kq	1138	4	expression	expression	NN
cord-010027-r0tl01kq	1138	5	of	of	IN
cord-010027-r0tl01kq	1138	6	RA	RA	NNP
cord-010027-r0tl01kq	1138	7	-	-	HYPH
cord-010027-r0tl01kq	1138	8	genes	gene	NNS
cord-010027-r0tl01kq	1138	9	,	,	,
cord-010027-r0tl01kq	1138	10	suggesting	suggest	VBG
cord-010027-r0tl01kq	1138	11	a	a	DT
cord-010027-r0tl01kq	1138	12	more	more	RBR
cord-010027-r0tl01kq	1138	13	immature	immature	JJ
cord-010027-r0tl01kq	1138	14	,	,	,
cord-010027-r0tl01kq	1138	15	less	less	RBR
cord-010027-r0tl01kq	1138	16	differentiated	differentiated	JJ
cord-010027-r0tl01kq	1138	17	phenotype	phenotype	NN
cord-010027-r0tl01kq	1138	18	.	.	.
cord-010027-r0tl01kq	1139	1	Gene	Gene	NNP
cord-010027-r0tl01kq	1139	2	and	and	CC
cord-010027-r0tl01kq	1139	3	mircoRNA	mircoRNA	NNP
cord-010027-r0tl01kq	1139	4	arrays	array	NNS
cord-010027-r0tl01kq	1139	5	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	1139	6	that	that	IN
cord-010027-r0tl01kq	1139	7	holoclones	holoclone	NNS
cord-010027-r0tl01kq	1139	8	downregulated	downregulate	VBD
cord-010027-r0tl01kq	1139	9	a	a	DT
cord-010027-r0tl01kq	1139	10	number	number	NN
cord-010027-r0tl01kq	1139	11	of	of	IN
cord-010027-r0tl01kq	1139	12	stem	stem	NN
cord-010027-r0tl01kq	1139	13	cell	cell	NN
cord-010027-r0tl01kq	1139	14	differentiation	differentiation	NN
cord-010027-r0tl01kq	1139	15	regulators	regulator	NNS
cord-010027-r0tl01kq	1139	16	while	while	IN
cord-010027-r0tl01kq	1139	17	displaying	display	VBG
cord-010027-r0tl01kq	1139	18	enhanced	enhanced	JJ
cord-010027-r0tl01kq	1139	19	regulation	regulation	NN
cord-010027-r0tl01kq	1139	20	of	of	IN
cord-010027-r0tl01kq	1139	21	G2	G2	NNP
cord-010027-r0tl01kq	1139	22	to	to	IN
cord-010027-r0tl01kq	1139	23	M	M	NNP
cord-010027-r0tl01kq	1139	24	transition	transition	NN
cord-010027-r0tl01kq	1139	25	and	and	CC
cord-010027-r0tl01kq	1139	26	the	the	DT
cord-010027-r0tl01kq	1139	27	mitotic	mitotic	JJ
cord-010027-r0tl01kq	1139	28	spindle	spindle	NN
cord-010027-r0tl01kq	1139	29	checkpoint	checkpoint	NN
cord-010027-r0tl01kq	1139	30	components	component	NNS
cord-010027-r0tl01kq	1139	31	of	of	IN
cord-010027-r0tl01kq	1139	32	the	the	DT
cord-010027-r0tl01kq	1139	33	cell	cell	NN
cord-010027-r0tl01kq	1139	34	cycle	cycle	NN
cord-010027-r0tl01kq	1139	35	.	.	.
cord-010027-r0tl01kq	1140	1	PC3	PC3	NNP
cord-010027-r0tl01kq	1140	2	holoclones	holoclones	NNP
cord-010027-r0tl01kq	1140	3	displayed	display	VBD
cord-010027-r0tl01kq	1140	4	pronounced	pronounce	VBN
cord-010027-r0tl01kq	1140	5	downregulation	downregulation	NN
cord-010027-r0tl01kq	1140	6	of	of	IN
cord-010027-r0tl01kq	1140	7	known	know	VBN
cord-010027-r0tl01kq	1140	8	regulators	regulator	NNS
cord-010027-r0tl01kq	1140	9	of	of	IN
cord-010027-r0tl01kq	1140	10	osteoblast	osteoblast	JJ
cord-010027-r0tl01kq	1140	11	differentiation	differentiation	NN
cord-010027-r0tl01kq	1140	12	from	from	IN
cord-010027-r0tl01kq	1140	13	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	1140	14	stem	stem	NN
cord-010027-r0tl01kq	1140	15	cells	cell	NNS
cord-010027-r0tl01kq	1140	16	and	and	CC
cord-010027-r0tl01kq	1140	17	Epithelial	Epithelial	NNP
cord-010027-r0tl01kq	1140	18	Mesenchymal	Mesenchymal	NNP
cord-010027-r0tl01kq	1140	19	Transition	Transition	NNP
cord-010027-r0tl01kq	1140	20	.	.	.
cord-010027-r0tl01kq	1141	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1141	2	:	:	:
cord-010027-r0tl01kq	1142	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1142	2	results	result	NNS
cord-010027-r0tl01kq	1142	3	suggest	suggest	VBP
cord-010027-r0tl01kq	1142	4	that	that	IN
cord-010027-r0tl01kq	1142	5	some	some	DT
cord-010027-r0tl01kq	1142	6	PCa	pca	NN
cord-010027-r0tl01kq	1142	7	cells	cell	NNS
cord-010027-r0tl01kq	1142	8	retain	retain	VBP
cord-010027-r0tl01kq	1142	9	the	the	DT
cord-010027-r0tl01kq	1142	10	ability	ability	NN
cord-010027-r0tl01kq	1142	11	to	to	TO
cord-010027-r0tl01kq	1142	12	transition	transition	VB
cord-010027-r0tl01kq	1142	13	to	to	IN
cord-010027-r0tl01kq	1142	14	a	a	DT
cord-010027-r0tl01kq	1142	15	more	more	RBR
cord-010027-r0tl01kq	1142	16	immature	immature	JJ
cord-010027-r0tl01kq	1142	17	state	state	NN
cord-010027-r0tl01kq	1142	18	in	in	IN
cord-010027-r0tl01kq	1142	19	which	which	WDT
cord-010027-r0tl01kq	1142	20	differentiation	differentiation	NN
cord-010027-r0tl01kq	1142	21	and	and	CC
cord-010027-r0tl01kq	1142	22	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1142	23	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	1142	24	are	be	VBP
cord-010027-r0tl01kq	1142	25	changed	change	VBN
cord-010027-r0tl01kq	1142	26	.	.	.
cord-010027-r0tl01kq	1143	1	The	the	DT
cord-010027-r0tl01kq	1143	2	highlighting	highlighting	NN
cord-010027-r0tl01kq	1143	3	of	of	IN
cord-010027-r0tl01kq	1143	4	osteoblast	osteoblast	JJ
cord-010027-r0tl01kq	1143	5	differentiation	differentiation	NN
cord-010027-r0tl01kq	1143	6	regulators	regulator	NNS
cord-010027-r0tl01kq	1143	7	in	in	IN
cord-010027-r0tl01kq	1143	8	this	this	DT
cord-010027-r0tl01kq	1143	9	mechanism	mechanism	NN
cord-010027-r0tl01kq	1143	10	is	be	VBZ
cord-010027-r0tl01kq	1143	11	particularly	particularly	RB
cord-010027-r0tl01kq	1143	12	notable	notable	JJ
cord-010027-r0tl01kq	1143	13	,	,	,
cord-010027-r0tl01kq	1143	14	considering	consider	VBG
cord-010027-r0tl01kq	1143	15	the	the	DT
cord-010027-r0tl01kq	1143	16	propensity	propensity	NN
cord-010027-r0tl01kq	1143	17	of	of	IN
cord-010027-r0tl01kq	1143	18	PCa	pca	NN
cord-010027-r0tl01kq	1143	19	to	to	TO
cord-010027-r0tl01kq	1143	20	metastasize	metastasize	VB
cord-010027-r0tl01kq	1143	21	to	to	IN
cord-010027-r0tl01kq	1143	22	bone	bone	NN
cord-010027-r0tl01kq	1143	23	.	.	.
cord-010027-r0tl01kq	1144	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1144	2	examined	examine	VBD
cord-010027-r0tl01kq	1144	3	by	by	IN
cord-010027-r0tl01kq	1144	4	flow	flow	NN
cord-010027-r0tl01kq	1144	5	cytometetry	cytometetry	NNP
cord-010027-r0tl01kq	1144	6	the	the	DT
cord-010027-r0tl01kq	1144	7	interaction	interaction	NN
cord-010027-r0tl01kq	1144	8	in	in	IN
cord-010027-r0tl01kq	1144	9	vitro	vitro	FW
cord-010027-r0tl01kq	1144	10	between	between	IN
cord-010027-r0tl01kq	1144	11	platelets	platelet	NNS
cord-010027-r0tl01kq	1144	12	and	and	CC
cord-010027-r0tl01kq	1144	13	15	15	CD
cord-010027-r0tl01kq	1144	14	human	human	JJ
cord-010027-r0tl01kq	1144	15	cancer	cancer	NN
cord-010027-r0tl01kq	1144	16	cell	cell	NN
cord-010027-r0tl01kq	1144	17	lines	line	NNS
cord-010027-r0tl01kq	1144	18	of	of	IN
cord-010027-r0tl01kq	1144	19	different	different	JJ
cord-010027-r0tl01kq	1144	20	origin	origin	NN
cord-010027-r0tl01kq	1144	21	and	and	CC
cord-010027-r0tl01kq	1144	22	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1144	23	potential	potential	NN
cord-010027-r0tl01kq	1144	24	.	.	.
cord-010027-r0tl01kq	1145	1	The	the	DT
cord-010027-r0tl01kq	1145	2	EMT	EMT	NNP
cord-010027-r0tl01kq	1145	3	profile	profile	NN
cord-010027-r0tl01kq	1145	4	of	of	IN
cord-010027-r0tl01kq	1145	5	cells	cell	NNS
cord-010027-r0tl01kq	1145	6	24hr	24hr	JJ
cord-010027-r0tl01kq	1145	7	post	post	NN
cord-010027-r0tl01kq	1145	8	platelet	platelet	NN
cord-010027-r0tl01kq	1145	9	exposure	exposure	NN
cord-010027-r0tl01kq	1145	10	was	be	VBD
cord-010027-r0tl01kq	1145	11	assessed	assess	VBN
cord-010027-r0tl01kq	1145	12	by	by	IN
cord-010027-r0tl01kq	1145	13	morphology	morphology	NN
cord-010027-r0tl01kq	1145	14	and	and	CC
cord-010027-r0tl01kq	1145	15	gene	gene	NN
cord-010027-r0tl01kq	1145	16	expression	expression	NN
cord-010027-r0tl01kq	1145	17	analysis	analysis	NN
cord-010027-r0tl01kq	1145	18	(	(	-LRB-
cord-010027-r0tl01kq	1145	19	RT	RT	NNP
cord-010027-r0tl01kq	1145	20	-	-	HYPH
cord-010027-r0tl01kq	1145	21	PCR	PCR	NNP
cord-010027-r0tl01kq	1145	22	)	)	-RRB-
cord-010027-r0tl01kq	1145	23	.	.	.
cord-010027-r0tl01kq	1146	1	Here	here	RB
cord-010027-r0tl01kq	1146	2	we	-PRON-	PRP
cord-010027-r0tl01kq	1146	3	showed	show	VBD
cord-010027-r0tl01kq	1146	4	that	that	IN
cord-010027-r0tl01kq	1146	5	platelet	platelet	NN
cord-010027-r0tl01kq	1146	6	cloaking	cloaking	NN
cord-010027-r0tl01kq	1146	7	of	of	IN
cord-010027-r0tl01kq	1146	8	cancer	cancer	NN
cord-010027-r0tl01kq	1146	9	cells	cell	NNS
cord-010027-r0tl01kq	1146	10	is	be	VBZ
cord-010027-r0tl01kq	1146	11	universal	universal	JJ
cord-010027-r0tl01kq	1146	12	,	,	,
cord-010027-r0tl01kq	1146	13	occurring	occur	VBG
cord-010027-r0tl01kq	1146	14	across	across	IN
cord-010027-r0tl01kq	1146	15	all	all	DT
cord-010027-r0tl01kq	1146	16	7	7	CD
cord-010027-r0tl01kq	1146	17	tumour	tumour	NN
cord-010027-r0tl01kq	1146	18	types	type	NNS
cord-010027-r0tl01kq	1146	19	examined	examine	VBD
cord-010027-r0tl01kq	1146	20	.	.	.
cord-010027-r0tl01kq	1147	1	However	however	RB
cord-010027-r0tl01kq	1147	2	,	,	,
cord-010027-r0tl01kq	1147	3	it	-PRON-	PRP
cord-010027-r0tl01kq	1147	4	is	be	VBZ
cord-010027-r0tl01kq	1147	5	heterogeneous	heterogeneous	JJ
cord-010027-r0tl01kq	1147	6	with	with	IN
cord-010027-r0tl01kq	1147	7	adhesion	adhesion	NN
cord-010027-r0tl01kq	1147	8	rates	rate	NNS
cord-010027-r0tl01kq	1147	9	varying	vary	VBG
cord-010027-r0tl01kq	1147	10	both	both	CC
cord-010027-r0tl01kq	1147	11	across	across	IN
cord-010027-r0tl01kq	1147	12	and	and	CC
cord-010027-r0tl01kq	1147	13	within	within	IN
cord-010027-r0tl01kq	1147	14	tumour	tumour	NN
cord-010027-r0tl01kq	1147	15	types	type	NNS
cord-010027-r0tl01kq	1147	16	,	,	,
cord-010027-r0tl01kq	1147	17	from	from	IN
cord-010027-r0tl01kq	1147	18	35	35	CD
cord-010027-r0tl01kq	1147	19	%	%	NN
cord-010027-r0tl01kq	1147	20	(	(	-LRB-
cord-010027-r0tl01kq	1147	21	PC3-metastatic	pc3-metastatic	JJ
cord-010027-r0tl01kq	1147	22	prostate	prostate	NN
cord-010027-r0tl01kq	1147	23	cancer	cancer	NN
cord-010027-r0tl01kq	1147	24	)	)	-RRB-
cord-010027-r0tl01kq	1147	25	to	to	IN
cord-010027-r0tl01kq	1147	26	83	83	CD
cord-010027-r0tl01kq	1147	27	%	%	NN
cord-010027-r0tl01kq	1147	28	(	(	-LRB-
cord-010027-r0tl01kq	1147	29	SKMES1-metastatic	SKMES1-metastatic	NNP
cord-010027-r0tl01kq	1147	30	lung	lung	NN
cord-010027-r0tl01kq	1147	31	cancer	cancer	NN
cord-010027-r0tl01kq	1147	32	)	)	-RRB-
cord-010027-r0tl01kq	1147	33	.	.	.
cord-010027-r0tl01kq	1148	1	Changes	change	NNS
cord-010027-r0tl01kq	1148	2	indicative	indicative	JJ
cord-010027-r0tl01kq	1148	3	of	of	IN
cord-010027-r0tl01kq	1148	4	EMT	EMT	NNP
cord-010027-r0tl01kq	1148	5	were	be	VBD
cord-010027-r0tl01kq	1148	6	seen	see	VBN
cord-010027-r0tl01kq	1148	7	in	in	IN
cord-010027-r0tl01kq	1148	8	all	all	DT
cord-010027-r0tl01kq	1148	9	cell	cell	NN
cord-010027-r0tl01kq	1148	10	lines	line	NNS
cord-010027-r0tl01kq	1148	11	.	.	.
cord-010027-r0tl01kq	1149	1	However	however	RB
cord-010027-r0tl01kq	1149	2	,	,	,
cord-010027-r0tl01kq	1149	3	again	again	RB
cord-010027-r0tl01kq	1149	4	they	-PRON-	PRP
cord-010027-r0tl01kq	1149	5	were	be	VBD
cord-010027-r0tl01kq	1149	6	heterogeneous	heterogeneous	JJ
cord-010027-r0tl01kq	1149	7	in	in	IN
cord-010027-r0tl01kq	1149	8	nature	nature	NN
cord-010027-r0tl01kq	1149	9	;	;	:
cord-010027-r0tl01kq	1149	10	with	with	IN
cord-010027-r0tl01kq	1149	11	morphology	morphology	NN
cord-010027-r0tl01kq	1149	12	changes	change	NNS
cord-010027-r0tl01kq	1149	13	akin	akin	JJ
cord-010027-r0tl01kq	1149	14	to	to	IN
cord-010027-r0tl01kq	1149	15	EMT	EMT	NNP
cord-010027-r0tl01kq	1149	16	observed	observe	VBD
cord-010027-r0tl01kq	1149	17	at	at	IN
cord-010027-r0tl01kq	1149	18	varying	vary	VBG
cord-010027-r0tl01kq	1149	19	degrees	degree	NNS
cord-010027-r0tl01kq	1149	20	across	across	IN
cord-010027-r0tl01kq	1149	21	the	the	DT
cord-010027-r0tl01kq	1149	22	cancer	cancer	NN
cord-010027-r0tl01kq	1149	23	types	type	NNS
cord-010027-r0tl01kq	1149	24	.	.	.
cord-010027-r0tl01kq	1150	1	Also	also	RB
cord-010027-r0tl01kq	1150	2	,	,	,
cord-010027-r0tl01kq	1150	3	there	there	EX
cord-010027-r0tl01kq	1150	4	was	be	VBD
cord-010027-r0tl01kq	1150	5	no	no	DT
cord-010027-r0tl01kq	1150	6	consistent	consistent	JJ
cord-010027-r0tl01kq	1150	7	pattern	pattern	NN
cord-010027-r0tl01kq	1150	8	to	to	IN
cord-010027-r0tl01kq	1150	9	the	the	DT
cord-010027-r0tl01kq	1150	10	EMT	EMT	NNP
cord-010027-r0tl01kq	1150	11	-	-	HYPH
cord-010027-r0tl01kq	1150	12	like	like	JJ
cord-010027-r0tl01kq	1150	13	gene	gene	NN
cord-010027-r0tl01kq	1150	14	expression	expression	NN
cord-010027-r0tl01kq	1150	15	changes	change	NNS
cord-010027-r0tl01kq	1150	16	seen	see	VBN
cord-010027-r0tl01kq	1150	17	,	,	,
cord-010027-r0tl01kq	1150	18	with	with	IN
cord-010027-r0tl01kq	1150	19	one	one	CD
cord-010027-r0tl01kq	1150	20	exception	exception	NN
cord-010027-r0tl01kq	1150	21	a	a	DT
cord-010027-r0tl01kq	1150	22	significant	significant	JJ
cord-010027-r0tl01kq	1150	23	increase	increase	NN
cord-010027-r0tl01kq	1150	24	in	in	IN
cord-010027-r0tl01kq	1150	25	the	the	DT
cord-010027-r0tl01kq	1150	26	expression	expression	NN
cord-010027-r0tl01kq	1150	27	of	of	IN
cord-010027-r0tl01kq	1150	28	plasminogen	plasminogen	NN
cord-010027-r0tl01kq	1150	29	activator	activator	NN
cord-010027-r0tl01kq	1150	30	inhibitor	inhibitor	NN
cord-010027-r0tl01kq	1150	31	1	1	CD
cord-010027-r0tl01kq	1151	1	(	(	-LRB-
cord-010027-r0tl01kq	1151	2	PAI-1)was	PAI-1)was	NNP
cord-010027-r0tl01kq	1151	3	observed	observe	VBN
cord-010027-r0tl01kq	1151	4	in	in	IN
cord-010027-r0tl01kq	1151	5	93	93	CD
cord-010027-r0tl01kq	1151	6	%	%	NN
cord-010027-r0tl01kq	1151	7	of	of	IN
cord-010027-r0tl01kq	1151	8	the	the	DT
cord-010027-r0tl01kq	1151	9	cell	cell	NN
cord-010027-r0tl01kq	1151	10	lines	line	NNS
cord-010027-r0tl01kq	1151	11	examined	examine	VBN
cord-010027-r0tl01kq	1151	12	.	.	.
cord-010027-r0tl01kq	1152	1	In	in	IN
cord-010027-r0tl01kq	1152	2	this	this	DT
cord-010027-r0tl01kq	1152	3	study	study	NN
cord-010027-r0tl01kq	1152	4	we	-PRON-	PRP
cord-010027-r0tl01kq	1152	5	describe	describe	VBP
cord-010027-r0tl01kq	1152	6	the	the	DT
cord-010027-r0tl01kq	1152	7	universal	universal	JJ
cord-010027-r0tl01kq	1152	8	nature	nature	NN
cord-010027-r0tl01kq	1152	9	of	of	IN
cord-010027-r0tl01kq	1152	10	platelet	platelet	NN
cord-010027-r0tl01kq	1152	11	cloaking	cloaking	NN
cord-010027-r0tl01kq	1152	12	and	and	CC
cord-010027-r0tl01kq	1152	13	that	that	IN
cord-010027-r0tl01kq	1152	14	even	even	RB
cord-010027-r0tl01kq	1152	15	though	though	IN
cord-010027-r0tl01kq	1152	16	the	the	DT
cord-010027-r0tl01kq	1152	17	interaction	interaction	NN
cord-010027-r0tl01kq	1152	18	is	be	VBZ
cord-010027-r0tl01kq	1152	19	not	not	RB
cord-010027-r0tl01kq	1152	20	inducing	induce	VBG
cord-010027-r0tl01kq	1152	21	precisely	precisely	RB
cord-010027-r0tl01kq	1152	22	the	the	DT
cord-010027-r0tl01kq	1152	23	same	same	JJ
cord-010027-r0tl01kq	1152	24	molecular	molecular	JJ
cord-010027-r0tl01kq	1152	25	changes	change	NNS
cord-010027-r0tl01kq	1152	26	in	in	IN
cord-010027-r0tl01kq	1152	27	all	all	PDT
cord-010027-r0tl01kq	1152	28	the	the	DT
cord-010027-r0tl01kq	1152	29	cancer	cancer	NN
cord-010027-r0tl01kq	1152	30	cells	cell	NNS
cord-010027-r0tl01kq	1152	31	;	;	:
cord-010027-r0tl01kq	1152	32	overall	overall	RB
cord-010027-r0tl01kq	1152	33	it	-PRON-	PRP
cord-010027-r0tl01kq	1152	34	is	be	VBZ
cord-010027-r0tl01kq	1152	35	driving	drive	VBG
cord-010027-r0tl01kq	1152	36	these	these	DT
cord-010027-r0tl01kq	1152	37	cells	cell	NNS
cord-010027-r0tl01kq	1152	38	into	into	IN
cord-010027-r0tl01kq	1152	39	a	a	DT
cord-010027-r0tl01kq	1152	40	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	1152	41	phenotype	phenotype	NN
cord-010027-r0tl01kq	1152	42	.	.	.
cord-010027-r0tl01kq	1153	1	Giant	giant	JJ
cord-010027-r0tl01kq	1153	2	cell	cell	NN
cord-010027-r0tl01kq	1153	3	tumours	tumour	NNS
cord-010027-r0tl01kq	1153	4	of	of	IN
cord-010027-r0tl01kq	1153	5	bone	bone	NN
cord-010027-r0tl01kq	1153	6	(	(	-LRB-
cord-010027-r0tl01kq	1153	7	GCT	GCT	NNP
cord-010027-r0tl01kq	1153	8	)	)	-RRB-
cord-010027-r0tl01kq	1153	9	are	be	VBP
cord-010027-r0tl01kq	1153	10	primary	primary	JJ
cord-010027-r0tl01kq	1153	11	locally	locally	RB
cord-010027-r0tl01kq	1153	12	aggressive	aggressive	JJ
cord-010027-r0tl01kq	1153	13	bone	bone	NN
cord-010027-r0tl01kq	1153	14	tumours	tumour	NNS
cord-010027-r0tl01kq	1153	15	with	with	IN
cord-010027-r0tl01kq	1153	16	a	a	DT
cord-010027-r0tl01kq	1153	17	recurrence	recurrence	NN
cord-010027-r0tl01kq	1153	18	rate	rate	NN
cord-010027-r0tl01kq	1153	19	of	of	IN
cord-010027-r0tl01kq	1153	20	up	up	IN
cord-010027-r0tl01kq	1153	21	to	to	TO
cord-010027-r0tl01kq	1153	22	~30	~30	CD
cord-010027-r0tl01kq	1153	23	%	%	NN
cord-010027-r0tl01kq	1153	24	.	.	.
cord-010027-r0tl01kq	1154	1	The	the	DT
cord-010027-r0tl01kq	1154	2	tumour	tumour	NN
cord-010027-r0tl01kq	1154	3	is	be	VBZ
cord-010027-r0tl01kq	1154	4	characterised	characterise	VBN
cord-010027-r0tl01kq	1154	5	by	by	IN
cord-010027-r0tl01kq	1154	6	numerous	numerous	JJ
cord-010027-r0tl01kq	1154	7	osteoclasts	osteoclast	NNS
cord-010027-r0tl01kq	1154	8	and	and	CC
cord-010027-r0tl01kq	1154	9	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	1154	10	stromal	stromal	JJ
cord-010027-r0tl01kq	1154	11	cells	cell	NNS
cord-010027-r0tl01kq	1154	12	.	.	.
cord-010027-r0tl01kq	1155	1	Making	make	VBG
cord-010027-r0tl01kq	1155	2	a	a	DT
cord-010027-r0tl01kq	1155	3	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1155	4	can	can	MD
cord-010027-r0tl01kq	1155	5	be	be	VB
cord-010027-r0tl01kq	1155	6	challenging	challenging	JJ
cord-010027-r0tl01kq	1155	7	because	because	IN
cord-010027-r0tl01kq	1155	8	the	the	DT
cord-010027-r0tl01kq	1155	9	differential	differential	JJ
cord-010027-r0tl01kq	1155	10	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1155	11	incudes	incude	VBZ
cord-010027-r0tl01kq	1155	12	an	an	DT
cord-010027-r0tl01kq	1155	13	array	array	NN
cord-010027-r0tl01kq	1155	14	of	of	IN
cord-010027-r0tl01kq	1155	15	benign	benign	JJ
cord-010027-r0tl01kq	1155	16	osteoclast	osteoclast	JJ
cord-010027-r0tl01kq	1155	17	-	-	HYPH
cord-010027-r0tl01kq	1155	18	rich	rich	JJ
cord-010027-r0tl01kq	1155	19	tumours	tumour	NNS
cord-010027-r0tl01kq	1155	20	but	but	CC
cord-010027-r0tl01kq	1155	21	also	also	RB
cord-010027-r0tl01kq	1155	22	osteoclast	osteoclast	NN
cord-010027-r0tl01kq	1155	23	-	-	HYPH
cord-010027-r0tl01kq	1155	24	rich	rich	JJ
cord-010027-r0tl01kq	1155	25	osteosarcoma	osteosarcoma	NN
cord-010027-r0tl01kq	1155	26	.	.	.
cord-010027-r0tl01kq	1156	1	Recently	recently	RB
cord-010027-r0tl01kq	1156	2	the	the	DT
cord-010027-r0tl01kq	1156	3	occurrence	occurrence	NN
cord-010027-r0tl01kq	1156	4	of	of	IN
cord-010027-r0tl01kq	1156	5	H3F3A	H3F3A	NNP
cord-010027-r0tl01kq	1156	6	p.	p.	NN
cord-010027-r0tl01kq	1157	1	Gly34Try	Gly34Try	NNP
cord-010027-r0tl01kq	1157	2	(	(	-LRB-
cord-010027-r0tl01kq	1157	3	G34W	G34W	NNP
cord-010027-r0tl01kq	1157	4	)	)	-RRB-
cord-010027-r0tl01kq	1158	1	and	and	CC
cord-010027-r0tl01kq	1158	2	G34L	g34l	NN
cord-010027-r0tl01kq	1158	3	mutations	mutation	NNS
cord-010027-r0tl01kq	1158	4	was	be	VBD
cord-010027-r0tl01kq	1158	5	reported	report	VBN
cord-010027-r0tl01kq	1158	6	in	in	IN
cord-010027-r0tl01kq	1158	7	96	96	CD
cord-010027-r0tl01kq	1158	8	%	%	NN
cord-010027-r0tl01kq	1158	9	of	of	IN
cord-010027-r0tl01kq	1158	10	GCT	GCT	NNP
cord-010027-r0tl01kq	1158	11	,	,	,
cord-010027-r0tl01kq	1158	12	the	the	DT
cord-010027-r0tl01kq	1158	13	latter	latter	JJ
cord-010027-r0tl01kq	1158	14	occurring	occur	VBG
cord-010027-r0tl01kq	1158	15	rarely	rarely	RB
cord-010027-r0tl01kq	1158	16	.	.	.
cord-010027-r0tl01kq	1159	1	These	these	DT
cord-010027-r0tl01kq	1159	2	mutations	mutation	NNS
cord-010027-r0tl01kq	1159	3	occur	occur	VBP
cord-010027-r0tl01kq	1159	4	in	in	IN
cord-010027-r0tl01kq	1159	5	less	less	JJR
cord-010027-r0tl01kq	1159	6	than	than	IN
cord-010027-r0tl01kq	1159	7	2	2	CD
cord-010027-r0tl01kq	1159	8	%	%	NN
cord-010027-r0tl01kq	1159	9	of	of	IN
cord-010027-r0tl01kq	1159	10	>	>	$
cord-010027-r0tl01kq	1159	11	400	400	CD
cord-010027-r0tl01kq	1159	12	other	other	JJ
cord-010027-r0tl01kq	1159	13	benign	benign	JJ
cord-010027-r0tl01kq	1159	14	and	and	CC
cord-010027-r0tl01kq	1159	15	malignant	malignant	JJ
cord-010027-r0tl01kq	1159	16	bone	bone	NN
cord-010027-r0tl01kq	1159	17	tumours	tumour	NNS
cord-010027-r0tl01kq	1159	18	.	.	.
cord-010027-r0tl01kq	1160	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1160	2	has	have	VBZ
cord-010027-r0tl01kq	1160	3	been	be	VBN
cord-010027-r0tl01kq	1160	4	emphasised	emphasise	VBN
cord-010027-r0tl01kq	1160	5	that	that	IN
cord-010027-r0tl01kq	1160	6	a	a	DT
cord-010027-r0tl01kq	1160	7	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1160	8	of	of	IN
cord-010027-r0tl01kq	1160	9	GCT	GCT	NNP
cord-010027-r0tl01kq	1160	10	should	should	MD
cord-010027-r0tl01kq	1160	11	be	be	VB
cord-010027-r0tl01kq	1160	12	made	make	VBN
cord-010027-r0tl01kq	1160	13	with	with	IN
cord-010027-r0tl01kq	1160	14	caution	caution	NN
cord-010027-r0tl01kq	1160	15	in	in	IN
cord-010027-r0tl01kq	1160	16	the	the	DT
cord-010027-r0tl01kq	1160	17	absence	absence	NN
cord-010027-r0tl01kq	1160	18	of	of	IN
cord-010027-r0tl01kq	1160	19	detection	detection	NN
cord-010027-r0tl01kq	1160	20	of	of	IN
cord-010027-r0tl01kq	1160	21	G34W	G34W	NNP
cord-010027-r0tl01kq	1160	22	substitution	substitution	NN
cord-010027-r0tl01kq	1160	23	.	.	.
cord-010027-r0tl01kq	1161	1	Given	give	VBN
cord-010027-r0tl01kq	1161	2	the	the	DT
cord-010027-r0tl01kq	1161	3	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1161	4	importance	importance	NN
cord-010027-r0tl01kq	1161	5	of	of	IN
cord-010027-r0tl01kq	1161	6	G34W	G34W	NNP
cord-010027-r0tl01kq	1161	7	mutation	mutation	NN
cord-010027-r0tl01kq	1161	8	in	in	IN
cord-010027-r0tl01kq	1161	9	GCT	GCT	NNP
cord-010027-r0tl01kq	1161	10	,	,	,
cord-010027-r0tl01kq	1161	11	we	-PRON-	PRP
cord-010027-r0tl01kq	1161	12	have	have	VBP
cord-010027-r0tl01kq	1161	13	developed	develop	VBN
cord-010027-r0tl01kq	1161	14	a	a	DT
cord-010027-r0tl01kq	1161	15	simple	simple	JJ
cord-010027-r0tl01kq	1161	16	,	,	,
cord-010027-r0tl01kq	1161	17	quick	quick	JJ
cord-010027-r0tl01kq	1161	18	and	and	CC
cord-010027-r0tl01kq	1161	19	cost	cost	VB
cord-010027-r0tl01kq	1161	20	-	-	HYPH
cord-010027-r0tl01kq	1161	21	efficient	efficient	JJ
cord-010027-r0tl01kq	1161	22	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1161	23	test	test	NN
cord-010027-r0tl01kq	1161	24	to	to	TO
cord-010027-r0tl01kq	1161	25	detect	detect	VB
cord-010027-r0tl01kq	1161	26	this	this	DT
cord-010027-r0tl01kq	1161	27	recurrent	recurrent	JJ
cord-010027-r0tl01kq	1161	28	alteration	alteration	NN
cord-010027-r0tl01kq	1161	29	in	in	IN
cord-010027-r0tl01kq	1161	30	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1161	31	DNA	DNA	NNP
cord-010027-r0tl01kq	1161	32	using	use	VBG
cord-010027-r0tl01kq	1161	33	droplet	droplet	NN
cord-010027-r0tl01kq	1161	34	digital	digital	JJ
cord-010027-r0tl01kq	1161	35	PCR	PCR	NNP
cord-010027-r0tl01kq	1161	36	(	(	-LRB-
cord-010027-r0tl01kq	1161	37	ddPCR	ddPCR	NNP
cord-010027-r0tl01kq	1161	38	)	)	-RRB-
cord-010027-r0tl01kq	1161	39	.	.	.
cord-010027-r0tl01kq	1162	1	The	the	DT
cord-010027-r0tl01kq	1162	2	ddPCR	ddPCR	NNP
cord-010027-r0tl01kq	1162	3	data	datum	NNS
cord-010027-r0tl01kq	1162	4	from	from	IN
cord-010027-r0tl01kq	1162	5	DNA	DNA	NNP
cord-010027-r0tl01kq	1162	6	of	of	IN
cord-010027-r0tl01kq	1162	7	>	>	XX
cord-010027-r0tl01kq	1162	8	100	100	CD
cord-010027-r0tl01kq	1162	9	GCT	GCT	NNP
cord-010027-r0tl01kq	1162	10	have	have	VBP
cord-010027-r0tl01kq	1162	11	been	be	VBN
cord-010027-r0tl01kq	1162	12	compared	compare	VBN
cord-010027-r0tl01kq	1162	13	with	with	IN
cord-010027-r0tl01kq	1162	14	previous	previous	JJ
cord-010027-r0tl01kq	1162	15	'	'	``
cord-010027-r0tl01kq	1162	16	genotype	genotype	NN
cord-010027-r0tl01kq	1162	17	'	'	''
cord-010027-r0tl01kq	1162	18	data	datum	NNS
cord-010027-r0tl01kq	1162	19	generated	generate	VBN
cord-010027-r0tl01kq	1162	20	using	use	VBG
cord-010027-r0tl01kq	1162	21	Sanger	Sanger	NNP
cord-010027-r0tl01kq	1162	22	sequencing	sequencing	NN
cord-010027-r0tl01kq	1162	23	,	,	,
cord-010027-r0tl01kq	1162	24	and	and	CC
cord-010027-r0tl01kq	1162	25	a	a	DT
cord-010027-r0tl01kq	1162	26	number	number	NN
cord-010027-r0tl01kq	1162	27	of	of	IN
cord-010027-r0tl01kq	1162	28	next	next	JJ
cord-010027-r0tl01kq	1162	29	generation	generation	NN
cord-010027-r0tl01kq	1162	30	sequencing	sequencing	NN
cord-010027-r0tl01kq	1162	31	approaches	approach	NNS
cord-010027-r0tl01kq	1162	32	(	(	-LRB-
cord-010027-r0tl01kq	1162	33	whole	whole	JJ
cord-010027-r0tl01kq	1162	34	exome	exome	NN
cord-010027-r0tl01kq	1162	35	,	,	,
cord-010027-r0tl01kq	1162	36	whole	whole	JJ
cord-010027-r0tl01kq	1162	37	genome	genome	NN
cord-010027-r0tl01kq	1162	38	and	and	CC
cord-010027-r0tl01kq	1162	39	targeted	target	VBN
cord-010027-r0tl01kq	1162	40	panels	panel	NNS
cord-010027-r0tl01kq	1162	41	)	)	-RRB-
cord-010027-r0tl01kq	1162	42	.	.	.
cord-010027-r0tl01kq	1163	1	The	the	DT
cord-010027-r0tl01kq	1163	2	G34W	G34W	NNS
cord-010027-r0tl01kq	1163	3	and	and	CC
cord-010027-r0tl01kq	1163	4	G34L	G34L	NNS
cord-010027-r0tl01kq	1163	5	can	can	MD
cord-010027-r0tl01kq	1163	6	both	both	DT
cord-010027-r0tl01kq	1163	7	be	be	VB
cord-010027-r0tl01kq	1163	8	detected	detect	VBN
cord-010027-r0tl01kq	1163	9	in	in	IN
cord-010027-r0tl01kq	1163	10	a	a	DT
cord-010027-r0tl01kq	1163	11	single	single	JJ
cord-010027-r0tl01kq	1163	12	assay	assay	NN
cord-010027-r0tl01kq	1163	13	.	.	.
cord-010027-r0tl01kq	1164	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1164	2	have	have	VBP
cord-010027-r0tl01kq	1164	3	demonstrated	demonstrate	VBN
cord-010027-r0tl01kq	1164	4	the	the	DT
cord-010027-r0tl01kq	1164	5	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	1164	6	,	,	,
cord-010027-r0tl01kq	1164	7	specificity	specificity	NN
cord-010027-r0tl01kq	1164	8	,	,	,
cord-010027-r0tl01kq	1164	9	repeatability	repeatability	NN
cord-010027-r0tl01kq	1164	10	and	and	CC
cord-010027-r0tl01kq	1164	11	robustness	robustness	NN
cord-010027-r0tl01kq	1164	12	of	of	IN
cord-010027-r0tl01kq	1164	13	the	the	DT
cord-010027-r0tl01kq	1164	14	test	test	NN
cord-010027-r0tl01kq	1164	15	to	to	TO
cord-010027-r0tl01kq	1164	16	be	be	VB
cord-010027-r0tl01kq	1164	17	very	very	RB
cord-010027-r0tl01kq	1164	18	high	high	JJ
cord-010027-r0tl01kq	1164	19	with	with	IN
cord-010027-r0tl01kq	1164	20	a	a	DT
cord-010027-r0tl01kq	1164	21	turnaround	turnaround	NN
cord-010027-r0tl01kq	1164	22	time	time	NN
cord-010027-r0tl01kq	1164	23	of	of	IN
cord-010027-r0tl01kq	1164	24	no	no	DT
cord-010027-r0tl01kq	1164	25	more	more	JJR
cord-010027-r0tl01kq	1164	26	than	than	IN
cord-010027-r0tl01kq	1164	27	5	5	CD
cord-010027-r0tl01kq	1164	28	working	working	NN
cord-010027-r0tl01kq	1164	29	days	day	NNS
cord-010027-r0tl01kq	1164	30	.	.	.
cord-010027-r0tl01kq	1165	1	As	as	IN
cord-010027-r0tl01kq	1165	2	~30	~30	CD
cord-010027-r0tl01kq	1165	3	%	%	NN
cord-010027-r0tl01kq	1165	4	of	of	IN
cord-010027-r0tl01kq	1165	5	GCT	GCT	NNP
cord-010027-r0tl01kq	1165	6	recur	recur	VBP
cord-010027-r0tl01kq	1165	7	locally	locally	RB
cord-010027-r0tl01kq	1165	8	following	follow	VBG
cord-010027-r0tl01kq	1165	9	curettage	curettage	NN
cord-010027-r0tl01kq	1165	10	a	a	DT
cord-010027-r0tl01kq	1165	11	blood	blood	NN
cord-010027-r0tl01kq	1165	12	test	test	NN
cord-010027-r0tl01kq	1165	13	would	would	MD
cord-010027-r0tl01kq	1165	14	be	be	VB
cord-010027-r0tl01kq	1165	15	valuable	valuable	JJ
cord-010027-r0tl01kq	1165	16	to	to	TO
cord-010027-r0tl01kq	1165	17	monitor	monitor	VB
cord-010027-r0tl01kq	1165	18	patients	patient	NNS
cord-010027-r0tl01kq	1165	19	.	.	.
cord-010027-r0tl01kq	1166	1	To	to	IN
cord-010027-r0tl01kq	1166	2	this	this	DT
cord-010027-r0tl01kq	1166	3	end	end	NN
cord-010027-r0tl01kq	1166	4	the	the	DT
cord-010027-r0tl01kq	1166	5	ddPCR	ddPCR	NNP
cord-010027-r0tl01kq	1166	6	test	test	NN
cord-010027-r0tl01kq	1166	7	also	also	RB
cord-010027-r0tl01kq	1166	8	shows	show	VBZ
cord-010027-r0tl01kq	1166	9	that	that	IN
cord-010027-r0tl01kq	1166	10	the	the	DT
cord-010027-r0tl01kq	1166	11	mutation	mutation	NN
cord-010027-r0tl01kq	1166	12	can	can	MD
cord-010027-r0tl01kq	1166	13	be	be	VB
cord-010027-r0tl01kq	1166	14	detected	detect	VBN
cord-010027-r0tl01kq	1166	15	in	in	IN
cord-010027-r0tl01kq	1166	16	plasma	plasma	NN
cord-010027-r0tl01kq	1166	17	.	.	.
cord-010027-r0tl01kq	1167	1	Typically	typically	RB
cord-010027-r0tl01kq	1167	2	resistant	resistant	JJ
cord-010027-r0tl01kq	1167	3	to	to	IN
cord-010027-r0tl01kq	1167	4	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	1167	5	and	and	CC
cord-010027-r0tl01kq	1167	6	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1167	7	,	,	,
cord-010027-r0tl01kq	1167	8	high	high	JJ
cord-010027-r0tl01kq	1167	9	grade	grade	NN
cord-010027-r0tl01kq	1167	10	disease	disease	NN
cord-010027-r0tl01kq	1167	11	has	have	VBZ
cord-010027-r0tl01kq	1167	12	been	be	VBN
cord-010027-r0tl01kq	1167	13	treated	treat	VBN
cord-010027-r0tl01kq	1167	14	by	by	IN
cord-010027-r0tl01kq	1167	15	surgery	surgery	NN
cord-010027-r0tl01kq	1167	16	for	for	IN
cord-010027-r0tl01kq	1167	17	more	more	JJR
cord-010027-r0tl01kq	1167	18	than	than	IN
cord-010027-r0tl01kq	1167	19	50	50	CD
cord-010027-r0tl01kq	1167	20	years	year	NNS
cord-010027-r0tl01kq	1167	21	.	.	.
cord-010027-r0tl01kq	1168	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1168	2	has	have	VBZ
cord-010027-r0tl01kq	1168	3	recently	recently	RB
cord-010027-r0tl01kq	1168	4	been	be	VBN
cord-010027-r0tl01kq	1168	5	shown	show	VBN
cord-010027-r0tl01kq	1168	6	that	that	IN
cord-010027-r0tl01kq	1168	7	IDH1	IDH1	NNP
cord-010027-r0tl01kq	1168	8	and	and	CC
cord-010027-r0tl01kq	1168	9	IDH2	IDH2	NNP
cord-010027-r0tl01kq	1168	10	mutations	mutation	NNS
cord-010027-r0tl01kq	1168	11	are	be	VBP
cord-010027-r0tl01kq	1168	12	present	present	JJ
cord-010027-r0tl01kq	1168	13	ab	ab	FW
cord-010027-r0tl01kq	1168	14	initio	initio	FW
cord-010027-r0tl01kq	1168	15	in	in	IN
cord-010027-r0tl01kq	1168	16	~60	~60	CD
cord-010027-r0tl01kq	1168	17	%	%	NN
cord-010027-r0tl01kq	1168	18	of	of	IN
cord-010027-r0tl01kq	1168	19	chondrosarcoma	chondrosarcoma	NN
cord-010027-r0tl01kq	1168	20	cases	case	NNS
cord-010027-r0tl01kq	1168	21	and	and	CC
cord-010027-r0tl01kq	1168	22	that	that	IN
cord-010027-r0tl01kq	1168	23	these	these	DT
cord-010027-r0tl01kq	1168	24	are	be	VBP
cord-010027-r0tl01kq	1168	25	retained	retain	VBN
cord-010027-r0tl01kq	1168	26	throughout	throughout	IN
cord-010027-r0tl01kq	1168	27	disease	disease	NN
cord-010027-r0tl01kq	1168	28	progression	progression	NN
cord-010027-r0tl01kq	1168	29	.	.	.
cord-010027-r0tl01kq	1169	1	This	this	DT
cord-010027-r0tl01kq	1169	2	has	have	VBZ
cord-010027-r0tl01kq	1169	3	opened	open	VBN
cord-010027-r0tl01kq	1169	4	up	up	RP
cord-010027-r0tl01kq	1169	5	a	a	DT
cord-010027-r0tl01kq	1169	6	number	number	NN
cord-010027-r0tl01kq	1169	7	of	of	IN
cord-010027-r0tl01kq	1169	8	new	new	JJ
cord-010027-r0tl01kq	1169	9	potential	potential	JJ
cord-010027-r0tl01kq	1169	10	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1169	11	,	,	,
cord-010027-r0tl01kq	1169	12	biomarker	biomarker	NN
cord-010027-r0tl01kq	1169	13	and	and	CC
cord-010027-r0tl01kq	1169	14	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	1169	15	options	option	NNS
cord-010027-r0tl01kq	1169	16	.	.	.
cord-010027-r0tl01kq	1170	1	Digital	Digital	NNP
cord-010027-r0tl01kq	1170	2	PCR	PCR	NNP
cord-010027-r0tl01kq	1170	3	is	be	VBZ
cord-010027-r0tl01kq	1170	4	currently	currently	RB
cord-010027-r0tl01kq	1170	5	the	the	DT
cord-010027-r0tl01kq	1170	6	most	most	RBS
cord-010027-r0tl01kq	1170	7	sensitive	sensitive	JJ
cord-010027-r0tl01kq	1170	8	and	and	CC
cord-010027-r0tl01kq	1170	9	accurate	accurate	JJ
cord-010027-r0tl01kq	1170	10	method	method	NN
cord-010027-r0tl01kq	1170	11	for	for	IN
cord-010027-r0tl01kq	1170	12	detecting	detect	VBG
cord-010027-r0tl01kq	1170	13	and	and	CC
cord-010027-r0tl01kq	1170	14	quantifying	quantify	VBG
cord-010027-r0tl01kq	1170	15	mutant	mutant	JJ
cord-010027-r0tl01kq	1170	16	DNA	dna	NN
cord-010027-r0tl01kq	1170	17	molecules	molecule	NNS
cord-010027-r0tl01kq	1170	18	.	.	.
cord-010027-r0tl01kq	1171	1	The	the	DT
cord-010027-r0tl01kq	1171	2	BioRad	BioRad	NNP
cord-010027-r0tl01kq	1171	3	QX200	QX200	NNP
cord-010027-r0tl01kq	1171	4	digital	digital	JJ
cord-010027-r0tl01kq	1171	5	PCR	PCR	NNP
cord-010027-r0tl01kq	1171	6	platform	platform	NN
cord-010027-r0tl01kq	1171	7	is	be	VBZ
cord-010027-r0tl01kq	1171	8	also	also	RB
cord-010027-r0tl01kq	1171	9	both	both	DT
cord-010027-r0tl01kq	1171	10	cost	cost	VBP
cord-010027-r0tl01kq	1171	11	effective	effective	JJ
cord-010027-r0tl01kq	1171	12	and	and	CC
cord-010027-r0tl01kq	1171	13	scalable	scalable	JJ
cord-010027-r0tl01kq	1171	14	.	.	.
cord-010027-r0tl01kq	1172	1	Using	use	VBG
cord-010027-r0tl01kq	1172	2	the	the	DT
cord-010027-r0tl01kq	1172	3	QX200	QX200	NNP
cord-010027-r0tl01kq	1172	4	platform	platform	NN
cord-010027-r0tl01kq	1172	5	,	,	,
cord-010027-r0tl01kq	1172	6	we	-PRON-	PRP
cord-010027-r0tl01kq	1172	7	have	have	VBP
cord-010027-r0tl01kq	1172	8	developed	develop	VBN
cord-010027-r0tl01kq	1172	9	assays	assay	NNS
cord-010027-r0tl01kq	1172	10	for	for	IN
cord-010027-r0tl01kq	1172	11	the	the	DT
cord-010027-r0tl01kq	1172	12	5	5	CD
cord-010027-r0tl01kq	1172	13	common	common	JJ
cord-010027-r0tl01kq	1172	14	IDH1	IDH1	NNP
cord-010027-r0tl01kq	1172	15	mutations	mutation	NNS
cord-010027-r0tl01kq	1172	16	and	and	CC
cord-010027-r0tl01kq	1172	17	the	the	DT
cord-010027-r0tl01kq	1172	18	1	1	CD
cord-010027-r0tl01kq	1172	19	common	common	JJ
cord-010027-r0tl01kq	1172	20	IDH2	IDH2	NNP
cord-010027-r0tl01kq	1172	21	mutation	mutation	NN
cord-010027-r0tl01kq	1172	22	.	.	.
cord-010027-r0tl01kq	1173	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1173	2	have	have	VBP
cord-010027-r0tl01kq	1173	3	developed	develop	VBN
cord-010027-r0tl01kq	1173	4	the	the	DT
cord-010027-r0tl01kq	1173	5	IDH1	IDH1	NNP
cord-010027-r0tl01kq	1173	6	assays	assay	NNS
cord-010027-r0tl01kq	1173	7	both	both	DT
cord-010027-r0tl01kq	1173	8	in	in	IN
cord-010027-r0tl01kq	1173	9	singleplex	singleplex	NN
cord-010027-r0tl01kq	1173	10	and	and	CC
cord-010027-r0tl01kq	1173	11	multiplex	multiplex	NN
cord-010027-r0tl01kq	1173	12	.	.	.
cord-010027-r0tl01kq	1174	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1174	2	have	have	VBP
cord-010027-r0tl01kq	1174	3	optimised	optimise	VBN
cord-010027-r0tl01kq	1174	4	and	and	CC
cord-010027-r0tl01kq	1174	5	validated	validate	VBN
cord-010027-r0tl01kq	1174	6	all	all	DT
cord-010027-r0tl01kq	1174	7	assays	assay	NNS
cord-010027-r0tl01kq	1174	8	in	in	IN
cord-010027-r0tl01kq	1174	9	tissue	tissue	NN
cord-010027-r0tl01kq	1174	10	samples	sample	NNS
cord-010027-r0tl01kq	1174	11	demonstrating	demonstrate	VBG
cord-010027-r0tl01kq	1174	12	both	both	DT
cord-010027-r0tl01kq	1174	13	high	high	JJ
cord-010027-r0tl01kq	1174	14	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	1174	15	and	and	CC
cord-010027-r0tl01kq	1174	16	specificity	specificity	NN
cord-010027-r0tl01kq	1174	17	when	when	WRB
cord-010027-r0tl01kq	1174	18	compared	compare	VBN
cord-010027-r0tl01kq	1174	19	to	to	IN
cord-010027-r0tl01kq	1174	20	previously	previously	RB
cord-010027-r0tl01kq	1174	21	genotypes	genotype	NNS
cord-010027-r0tl01kq	1174	22	samples	sample	NNS
cord-010027-r0tl01kq	1174	23	.	.	.
cord-010027-r0tl01kq	1175	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1175	2	have	have	VBP
cord-010027-r0tl01kq	1175	3	demonstrated	demonstrate	VBN
cord-010027-r0tl01kq	1175	4	that	that	IN
cord-010027-r0tl01kq	1175	5	the	the	DT
cord-010027-r0tl01kq	1175	6	assays	assay	NNS
cord-010027-r0tl01kq	1175	7	are	be	VBP
cord-010027-r0tl01kq	1175	8	quantitative	quantitative	JJ
cord-010027-r0tl01kq	1175	9	over	over	IN
cord-010027-r0tl01kq	1175	10	4	4	CD
cord-010027-r0tl01kq	1175	11	orders	order	NNS
cord-010027-r0tl01kq	1175	12	of	of	IN
cord-010027-r0tl01kq	1175	13	magnitude	magnitude	NN
cord-010027-r0tl01kq	1175	14	and	and	CC
cord-010027-r0tl01kq	1175	15	in	in	IN
cord-010027-r0tl01kq	1175	16	high	high	JJ
cord-010027-r0tl01kq	1175	17	quality	quality	NN
cord-010027-r0tl01kq	1175	18	DNA	dna	NN
cord-010027-r0tl01kq	1175	19	we	-PRON-	PRP
cord-010027-r0tl01kq	1175	20	can	can	MD
cord-010027-r0tl01kq	1175	21	detect	detect	VB
cord-010027-r0tl01kq	1175	22	IDH	IDH	NNP
cord-010027-r0tl01kq	1175	23	mutations	mutation	NNS
cord-010027-r0tl01kq	1175	24	at	at	IN
cord-010027-r0tl01kq	1175	25	below	below	IN
cord-010027-r0tl01kq	1175	26	1	1	CD
cord-010027-r0tl01kq	1175	27	mutant	mutant	JJ
cord-010027-r0tl01kq	1175	28	molecule	molecule	NN
cord-010027-r0tl01kq	1175	29	in	in	IN
cord-010027-r0tl01kq	1175	30	10,000	10,000	CD
cord-010027-r0tl01kq	1175	31	wild	wild	JJ
cord-010027-r0tl01kq	1175	32	type	type	NN
cord-010027-r0tl01kq	1175	33	molecules	molecule	NNS
cord-010027-r0tl01kq	1175	34	.	.	.
cord-010027-r0tl01kq	1176	1	In	in	IN
cord-010027-r0tl01kq	1176	2	a	a	DT
cord-010027-r0tl01kq	1176	3	pilot	pilot	NN
cord-010027-r0tl01kq	1176	4	study	study	NN
cord-010027-r0tl01kq	1176	5	,	,	,
cord-010027-r0tl01kq	1176	6	we	-PRON-	PRP
cord-010027-r0tl01kq	1176	7	have	have	VBP
cord-010027-r0tl01kq	1176	8	used	use	VBN
cord-010027-r0tl01kq	1176	9	digital	digital	JJ
cord-010027-r0tl01kq	1176	10	PCR	PCR	NNP
cord-010027-r0tl01kq	1176	11	to	to	TO
cord-010027-r0tl01kq	1176	12	analyse	analyse	VB
cord-010027-r0tl01kq	1176	13	circulating	circulate	VBG
cord-010027-r0tl01kq	1176	14	tumour	tumour	NN
cord-010027-r0tl01kq	1176	15	DNA	dna	NN
cord-010027-r0tl01kq	1176	16	levels	level	NNS
cord-010027-r0tl01kq	1176	17	in	in	IN
cord-010027-r0tl01kq	1176	18	plasma	plasma	NN
cord-010027-r0tl01kq	1176	19	taken	take	VBN
cord-010027-r0tl01kq	1176	20	pre	pre	NN
cord-010027-r0tl01kq	1176	21	-	-	NN
cord-010027-r0tl01kq	1176	22	surgery	surgery	NN
cord-010027-r0tl01kq	1176	23	from	from	IN
cord-010027-r0tl01kq	1176	24	14	14	CD
cord-010027-r0tl01kq	1176	25	patients	patient	NNS
cord-010027-r0tl01kq	1176	26	whose	whose	WP$
cord-010027-r0tl01kq	1176	27	chondrosarcoma	chondrosarcoma	NNP
cord-010027-r0tl01kq	1176	28	harbour	harbour	VB
cord-010027-r0tl01kq	1176	29	an	an	DT
cord-010027-r0tl01kq	1176	30	IDH1	IDH1	NNP
cord-010027-r0tl01kq	1176	31	mutation	mutation	NN
cord-010027-r0tl01kq	1176	32	.	.	.
cord-010027-r0tl01kq	1177	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1177	2	was	be	VBD
cord-010027-r0tl01kq	1177	3	possible	possible	JJ
cord-010027-r0tl01kq	1177	4	to	to	TO
cord-010027-r0tl01kq	1177	5	detect	detect	VB
cord-010027-r0tl01kq	1177	6	IDH1	IDH1	NNP
cord-010027-r0tl01kq	1177	7	mutant	mutant	JJ
cord-010027-r0tl01kq	1177	8	molecules	molecule	NNS
cord-010027-r0tl01kq	1177	9	in	in	IN
cord-010027-r0tl01kq	1177	10	plasma	plasma	NN
cord-010027-r0tl01kq	1177	11	of	of	IN
cord-010027-r0tl01kq	1177	12	all	all	DT
cord-010027-r0tl01kq	1177	13	Grade	Grade	NNP
cord-010027-r0tl01kq	1177	14	III	iii	CD
cord-010027-r0tl01kq	1177	15	samples	sample	NNS
cord-010027-r0tl01kq	1177	16	,	,	,
cord-010027-r0tl01kq	1177	17	50	50	CD
cord-010027-r0tl01kq	1177	18	%	%	NN
cord-010027-r0tl01kq	1177	19	of	of	IN
cord-010027-r0tl01kq	1177	20	Grade	Grade	NNP
cord-010027-r0tl01kq	1177	21	II	II	NNP
cord-010027-r0tl01kq	1177	22	and	and	CC
cord-010027-r0tl01kq	1177	23	none	none	NN
cord-010027-r0tl01kq	1177	24	of	of	IN
cord-010027-r0tl01kq	1177	25	the	the	DT
cord-010027-r0tl01kq	1177	26	Grade	Grade	NNP
cord-010027-r0tl01kq	1177	27	I	-PRON-	PRP
cord-010027-r0tl01kq	1177	28	samples	sample	NNS
cord-010027-r0tl01kq	1177	29	.	.	.
cord-010027-r0tl01kq	1178	1	In	in	IN
cord-010027-r0tl01kq	1178	2	4	4	CD
cord-010027-r0tl01kq	1178	3	of	of	IN
cord-010027-r0tl01kq	1178	4	these	these	DT
cord-010027-r0tl01kq	1178	5	cases	case	NNS
cord-010027-r0tl01kq	1178	6	where	where	WRB
cord-010027-r0tl01kq	1178	7	the	the	DT
cord-010027-r0tl01kq	1178	8	ctDNA	ctdna	NN
cord-010027-r0tl01kq	1178	9	was	be	VBD
cord-010027-r0tl01kq	1178	10	also	also	RB
cord-010027-r0tl01kq	1178	11	measured	measure	VBN
cord-010027-r0tl01kq	1178	12	post	post	RB
cord-010027-r0tl01kq	1178	13	-	-	JJ
cord-010027-r0tl01kq	1178	14	operatively	operatively	RB
cord-010027-r0tl01kq	1178	15	,	,	,
cord-010027-r0tl01kq	1178	16	the	the	DT
cord-010027-r0tl01kq	1178	17	levels	level	NNS
cord-010027-r0tl01kq	1178	18	of	of	IN
cord-010027-r0tl01kq	1178	19	ctDNA	ctdna	NN
cord-010027-r0tl01kq	1178	20	dropped	drop	VBD
cord-010027-r0tl01kq	1178	21	dramatically	dramatically	RB
cord-010027-r0tl01kq	1178	22	.	.	.
cord-010027-r0tl01kq	1179	1	Tumour	tumour	NN
cord-010027-r0tl01kq	1179	2	Necrosis	necrosis	NN
cord-010027-r0tl01kq	1179	3	Factor	Factor	NNP
cord-010027-r0tl01kq	1179	4	Receptor	Receptor	NNP
cord-010027-r0tl01kq	1179	5	,	,	,
cord-010027-r0tl01kq	1179	6	CD40	CD40	NNP
cord-010027-r0tl01kq	1179	7	,	,	,
cord-010027-r0tl01kq	1179	8	Gene	Gene	NNP
cord-010027-r0tl01kq	1179	9	Functions	Functions	NNPS
cord-010027-r0tl01kq	1179	10	as	as	IN
cord-010027-r0tl01kq	1179	11	an	an	DT
cord-010027-r0tl01kq	1179	12	Oncogene	oncogene	NN
cord-010027-r0tl01kq	1179	13	and	and	CC
cord-010027-r0tl01kq	1179	14	Promotes	promote	VBZ
cord-010027-r0tl01kq	1179	15	Cell	cell	NN
cord-010027-r0tl01kq	1179	16	Proliferation	proliferation	NN
cord-010027-r0tl01kq	1179	17	in	in	IN
cord-010027-r0tl01kq	1179	18	Colorectal	Colorectal	NNP
cord-010027-r0tl01kq	1179	19	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1179	20	Cell	Cell	NNP
cord-010027-r0tl01kq	1179	21	Lines	line	NNS
cord-010027-r0tl01kq	1179	22	P	p	NN
cord-010027-r0tl01kq	1179	23	HAA	HAA	NNP
cord-010027-r0tl01kq	1179	24	Almasmoum	Almasmoum	NNP
cord-010027-r0tl01kq	1179	25	;	;	:
cord-010027-r0tl01kq	1179	26	H	H	NNP
cord-010027-r0tl01kq	1179	27	Thorpe	Thorpe	NNP
cord-010027-r0tl01kq	1179	28	;	;	:
cord-010027-r0tl01kq	1180	1	M	M	NNP
cord-010027-r0tl01kq	1180	2	Ilyas	Ilyas	NNP
cord-010027-r0tl01kq	1180	3	Introduction	Introduction	NNP
cord-010027-r0tl01kq	1180	4	:	:	:
cord-010027-r0tl01kq	1181	1	CD40	CD40	NNP
cord-010027-r0tl01kq	1181	2	is	be	VBZ
cord-010027-r0tl01kq	1181	3	a	a	DT
cord-010027-r0tl01kq	1181	4	tumour	tumour	NN
cord-010027-r0tl01kq	1181	5	necrosis	necrosis	NN
cord-010027-r0tl01kq	1181	6	factor	factor	NN
cord-010027-r0tl01kq	1181	7	(	(	-LRB-
cord-010027-r0tl01kq	1181	8	TNF	TNF	NNP
cord-010027-r0tl01kq	1181	9	)	)	-RRB-
cord-010027-r0tl01kq	1181	10	receptor	receptor	NN
cord-010027-r0tl01kq	1181	11	which	which	WDT
cord-010027-r0tl01kq	1181	12	regulates	regulate	VBZ
cord-010027-r0tl01kq	1181	13	a	a	DT
cord-010027-r0tl01kq	1181	14	range	range	NN
cord-010027-r0tl01kq	1181	15	of	of	IN
cord-010027-r0tl01kq	1181	16	cellular	cellular	JJ
cord-010027-r0tl01kq	1181	17	responses	response	NNS
cord-010027-r0tl01kq	1181	18	.	.	.
cord-010027-r0tl01kq	1182	1	CD40	CD40	NNP
cord-010027-r0tl01kq	1182	2	is	be	VBZ
cord-010027-r0tl01kq	1182	3	activated	activate	VBN
cord-010027-r0tl01kq	1182	4	by	by	IN
cord-010027-r0tl01kq	1182	5	its	-PRON-	PRP$
cord-010027-r0tl01kq	1182	6	ligand	ligand	NN
cord-010027-r0tl01kq	1182	7	CD40L	cd40l	NN
cord-010027-r0tl01kq	1182	8	and	and	CC
cord-010027-r0tl01kq	1182	9	may	may	MD
cord-010027-r0tl01kq	1182	10	promote	promote	VB
cord-010027-r0tl01kq	1182	11	tumourigenesis	tumourigenesis	NN
cord-010027-r0tl01kq	1182	12	in	in	IN
cord-010027-r0tl01kq	1182	13	haematological	haematological	JJ
cord-010027-r0tl01kq	1182	14	cancers	cancer	NNS
cord-010027-r0tl01kq	1182	15	.	.	.
cord-010027-r0tl01kq	1183	1	However	however	RB
cord-010027-r0tl01kq	1183	2	,	,	,
cord-010027-r0tl01kq	1183	3	CD40	CD40	NNP
cord-010027-r0tl01kq	1183	4	functions	function	NNS
cord-010027-r0tl01kq	1183	5	as	as	IN
cord-010027-r0tl01kq	1183	6	a	a	DT
cord-010027-r0tl01kq	1183	7	tumour	tumour	NN
cord-010027-r0tl01kq	1183	8	suppressor	suppressor	NN
cord-010027-r0tl01kq	1183	9	in	in	IN
cord-010027-r0tl01kq	1183	10	solid	solid	JJ
cord-010027-r0tl01kq	1183	11	cancers	cancer	NNS
cord-010027-r0tl01kq	1183	12	.	.	.
cord-010027-r0tl01kq	1184	1	CD40	CD40	NNP
cord-010027-r0tl01kq	1184	2	maps	map	NNS
cord-010027-r0tl01kq	1184	3	to	to	TO
cord-010027-r0tl01kq	1184	4	chromosome	chromosome	VB
cord-010027-r0tl01kq	1184	5	20q13	20q13	CD
cord-010027-r0tl01kq	1184	6	,	,	,
cord-010027-r0tl01kq	1184	7	a	a	DT
cord-010027-r0tl01kq	1184	8	region	region	NN
cord-010027-r0tl01kq	1184	9	which	which	WDT
cord-010027-r0tl01kq	1184	10	is	be	VBZ
cord-010027-r0tl01kq	1184	11	amplified	amplify	VBN
cord-010027-r0tl01kq	1184	12	in	in	IN
cord-010027-r0tl01kq	1184	13	40	40	CD
cord-010027-r0tl01kq	1184	14	-	-	SYM
cord-010027-r0tl01kq	1184	15	50	50	CD
cord-010027-r0tl01kq	1184	16	%	%	NN
cord-010027-r0tl01kq	1184	17	of	of	IN
cord-010027-r0tl01kq	1184	18	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1184	19	cancer	cancer	NN
cord-010027-r0tl01kq	1184	20	(	(	-LRB-
cord-010027-r0tl01kq	1184	21	CRC	CRC	NNP
cord-010027-r0tl01kq	1184	22	)	)	-RRB-
cord-010027-r0tl01kq	1184	23	.	.	.
cord-010027-r0tl01kq	1185	1	The	the	DT
cord-010027-r0tl01kq	1185	2	functional	functional	JJ
cord-010027-r0tl01kq	1185	3	activities	activity	NNS
cord-010027-r0tl01kq	1185	4	of	of	IN
cord-010027-r0tl01kq	1185	5	CD40	CD40	NNP
cord-010027-r0tl01kq	1185	6	were	be	VBD
cord-010027-r0tl01kq	1185	7	tested	test	VBN
cord-010027-r0tl01kq	1185	8	in	in	IN
cord-010027-r0tl01kq	1185	9	CRC	CRC	NNP
cord-010027-r0tl01kq	1185	10	cell	cell	NN
cord-010027-r0tl01kq	1185	11	lines	line	NNS
cord-010027-r0tl01kq	1185	12	for	for	IN
cord-010027-r0tl01kq	1185	13	cell	cell	NN
cord-010027-r0tl01kq	1185	14	proliferation	proliferation	NN
cord-010027-r0tl01kq	1185	15	and	and	CC
cord-010027-r0tl01kq	1185	16	motility	motility	NN
cord-010027-r0tl01kq	1185	17	.	.	.
cord-010027-r0tl01kq	1186	1	Methods	method	NNS
cord-010027-r0tl01kq	1186	2	:	:	:
cord-010027-r0tl01kq	1187	1	Expression	expression	NN
cord-010027-r0tl01kq	1187	2	of	of	IN
cord-010027-r0tl01kq	1187	3	CD40	CD40	NNP
cord-010027-r0tl01kq	1187	4	was	be	VBD
cord-010027-r0tl01kq	1187	5	screened	screen	VBN
cord-010027-r0tl01kq	1187	6	in	in	IN
cord-010027-r0tl01kq	1187	7	CRC	CRC	NNP
cord-010027-r0tl01kq	1187	8	cell	cell	NN
cord-010027-r0tl01kq	1187	9	lines	line	NNS
cord-010027-r0tl01kq	1187	10	by	by	IN
cord-010027-r0tl01kq	1187	11	western	western	JJ
cord-010027-r0tl01kq	1187	12	blot	blot	NN
cord-010027-r0tl01kq	1187	13	.	.	.
cord-010027-r0tl01kq	1188	1	To	to	TO
cord-010027-r0tl01kq	1188	2	define	define	VB
cord-010027-r0tl01kq	1188	3	the	the	DT
cord-010027-r0tl01kq	1188	4	role	role	NN
cord-010027-r0tl01kq	1188	5	of	of	IN
cord-010027-r0tl01kq	1188	6	CD40	CD40	NNP
cord-010027-r0tl01kq	1188	7	in	in	IN
cord-010027-r0tl01kq	1188	8	human	human	JJ
cord-010027-r0tl01kq	1188	9	CRC	crc	NN
cord-010027-r0tl01kq	1188	10	,	,	,
cord-010027-r0tl01kq	1188	11	we	-PRON-	PRP
cord-010027-r0tl01kq	1188	12	knocked	knock	VBD
cord-010027-r0tl01kq	1188	13	down	down	RP
cord-010027-r0tl01kq	1188	14	CD40	CD40	NNP
cord-010027-r0tl01kq	1188	15	using	use	VBG
cord-010027-r0tl01kq	1188	16	small	small	JJ
cord-010027-r0tl01kq	1188	17	interfering	interfere	VBG
cord-010027-r0tl01kq	1188	18	RNA	RNA	NNP
cord-010027-r0tl01kq	1188	19	(	(	-LRB-
cord-010027-r0tl01kq	1188	20	siRNA	siRNA	NNP
cord-010027-r0tl01kq	1188	21	)	)	-RRB-
cord-010027-r0tl01kq	1188	22	and	and	CC
cord-010027-r0tl01kq	1188	23	the	the	DT
cord-010027-r0tl01kq	1188	24	knockdown	knockdown	NN
cord-010027-r0tl01kq	1188	25	was	be	VBD
cord-010027-r0tl01kq	1188	26	confirmed	confirm	VBN
cord-010027-r0tl01kq	1188	27	by	by	IN
cord-010027-r0tl01kq	1188	28	qPCR	qPCR	NNP
cord-010027-r0tl01kq	1188	29	and	and	CC
cord-010027-r0tl01kq	1188	30	western	western	JJ
cord-010027-r0tl01kq	1188	31	blot	blot	NN
cord-010027-r0tl01kq	1188	32	.	.	.
cord-010027-r0tl01kq	1189	1	The	the	DT
cord-010027-r0tl01kq	1189	2	PrestoBlue	PrestoBlue	NNP
cord-010027-r0tl01kq	1189	3	assay	assay	NN
cord-010027-r0tl01kq	1189	4	was	be	VBD
cord-010027-r0tl01kq	1189	5	used	use	VBN
cord-010027-r0tl01kq	1189	6	to	to	TO
cord-010027-r0tl01kq	1189	7	study	study	VB
cord-010027-r0tl01kq	1189	8	proliferation	proliferation	NN
cord-010027-r0tl01kq	1189	9	in	in	IN
cord-010027-r0tl01kq	1189	10	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1189	11	cell	cell	NN
cord-010027-r0tl01kq	1189	12	lines	line	NNS
cord-010027-r0tl01kq	1189	13	,	,	,
cord-010027-r0tl01kq	1189	14	and	and	CC
cord-010027-r0tl01kq	1189	15	flow	flow	VB
cord-010027-r0tl01kq	1189	16	cytometry	cytometry	NN
cord-010027-r0tl01kq	1189	17	to	to	TO
cord-010027-r0tl01kq	1189	18	study	study	VB
cord-010027-r0tl01kq	1189	19	the	the	DT
cord-010027-r0tl01kq	1189	20	cell	cell	NN
cord-010027-r0tl01kq	1189	21	cycle	cycle	NN
cord-010027-r0tl01kq	1189	22	.	.	.
cord-010027-r0tl01kq	1190	1	Transwell	Transwell	NNP
cord-010027-r0tl01kq	1190	2	migration	migration	NN
cord-010027-r0tl01kq	1190	3	and	and	CC
cord-010027-r0tl01kq	1190	4	wound	wound	VB
cord-010027-r0tl01kq	1190	5	healing	healing	NN
cord-010027-r0tl01kq	1190	6	assays	assay	NNS
cord-010027-r0tl01kq	1190	7	were	be	VBD
cord-010027-r0tl01kq	1190	8	performed	perform	VBN
cord-010027-r0tl01kq	1190	9	to	to	TO
cord-010027-r0tl01kq	1190	10	investigate	investigate	VB
cord-010027-r0tl01kq	1190	11	the	the	DT
cord-010027-r0tl01kq	1190	12	effect	effect	NN
cord-010027-r0tl01kq	1190	13	of	of	IN
cord-010027-r0tl01kq	1190	14	CD40	CD40	NNP
cord-010027-r0tl01kq	1190	15	on	on	IN
cord-010027-r0tl01kq	1190	16	cell	cell	NN
cord-010027-r0tl01kq	1190	17	motility	motility	NN
cord-010027-r0tl01kq	1190	18	in	in	IN
cord-010027-r0tl01kq	1190	19	CRC	CRC	NNP
cord-010027-r0tl01kq	1190	20	.	.	.
cord-010027-r0tl01kq	1191	1	Result	result	NN
cord-010027-r0tl01kq	1191	2	:	:	:
cord-010027-r0tl01kq	1192	1	CD40	CD40	NNP
cord-010027-r0tl01kq	1192	2	was	be	VBD
cord-010027-r0tl01kq	1192	3	expressed	express	VBN
cord-010027-r0tl01kq	1192	4	in	in	IN
cord-010027-r0tl01kq	1192	5	CRC	CRC	NNP
cord-010027-r0tl01kq	1192	6	cell	cell	NN
cord-010027-r0tl01kq	1192	7	lines	line	NNS
cord-010027-r0tl01kq	1193	1	HCT116	HCT116	NNP
cord-010027-r0tl01kq	1193	2	,	,	,
cord-010027-r0tl01kq	1193	3	RKO	RKO	NNP
cord-010027-r0tl01kq	1193	4	,	,	,
cord-010027-r0tl01kq	1193	5	DLD1	DLD1	NNP
cord-010027-r0tl01kq	1193	6	and	and	CC
cord-010027-r0tl01kq	1193	7	HT29	HT29	NNP
cord-010027-r0tl01kq	1193	8	,	,	,
cord-010027-r0tl01kq	1193	9	and	and	CC
cord-010027-r0tl01kq	1193	10	not	not	RB
cord-010027-r0tl01kq	1193	11	expressed	express	VBN
cord-010027-r0tl01kq	1193	12	in	in	IN
cord-010027-r0tl01kq	1193	13	SW480	SW480	NNP
cord-010027-r0tl01kq	1193	14	and	and	CC
cord-010027-r0tl01kq	1193	15	SW620	SW620	NNP
cord-010027-r0tl01kq	1193	16	cell	cell	NN
cord-010027-r0tl01kq	1193	17	lines	line	NNS
cord-010027-r0tl01kq	1193	18	.	.	.
cord-010027-r0tl01kq	1194	1	Knockdown	knockdown	NN
cord-010027-r0tl01kq	1194	2	of	of	IN
cord-010027-r0tl01kq	1194	3	CD40	CD40	NNP
cord-010027-r0tl01kq	1194	4	reduced	reduce	VBD
cord-010027-r0tl01kq	1194	5	cellular	cellular	JJ
cord-010027-r0tl01kq	1194	6	proliferation	proliferation	NN
cord-010027-r0tl01kq	1194	7	in	in	IN
cord-010027-r0tl01kq	1194	8	HCT116	HCT116	NNP
cord-010027-r0tl01kq	1194	9	(	(	-LRB-
cord-010027-r0tl01kq	1194	10	p=0.0158	p=0.0158	NNS
cord-010027-r0tl01kq	1194	11	)	)	-RRB-
cord-010027-r0tl01kq	1194	12	and	and	CC
cord-010027-r0tl01kq	1194	13	DLD1	DLD1	NNP
cord-010027-r0tl01kq	1194	14	(	(	-LRB-
cord-010027-r0tl01kq	1194	15	p=0.0020	p=0.0020	NN
cord-010027-r0tl01kq	1194	16	)	)	-RRB-
cord-010027-r0tl01kq	1194	17	cell	cell	NN
cord-010027-r0tl01kq	1194	18	lines	line	NNS
cord-010027-r0tl01kq	1194	19	.	.	.
cord-010027-r0tl01kq	1195	1	Knockdown	knockdown	NN
cord-010027-r0tl01kq	1195	2	of	of	IN
cord-010027-r0tl01kq	1195	3	CD40	CD40	NNP
cord-010027-r0tl01kq	1195	4	showed	show	VBD
cord-010027-r0tl01kq	1195	5	a	a	DT
cord-010027-r0tl01kq	1195	6	higher	high	JJR
cord-010027-r0tl01kq	1195	7	number	number	NN
cord-010027-r0tl01kq	1195	8	of	of	IN
cord-010027-r0tl01kq	1195	9	cells	cell	NNS
cord-010027-r0tl01kq	1195	10	in	in	IN
cord-010027-r0tl01kq	1195	11	the	the	DT
cord-010027-r0tl01kq	1195	12	sub	sub	JJ
cord-010027-r0tl01kq	1195	13	G0	g0	NN
cord-010027-r0tl01kq	1195	14	phase	phase	NN
cord-010027-r0tl01kq	1195	15	(	(	-LRB-
cord-010027-r0tl01kq	1195	16	dead	dead	JJ
cord-010027-r0tl01kq	1195	17	cells	cell	NNS
cord-010027-r0tl01kq	1195	18	)	)	-RRB-
cord-010027-r0tl01kq	1195	19	in	in	IN
cord-010027-r0tl01kq	1195	20	the	the	DT
cord-010027-r0tl01kq	1195	21	cell	cell	NN
cord-010027-r0tl01kq	1195	22	cycle	cycle	NN
cord-010027-r0tl01kq	1195	23	analysis	analysis	NN
cord-010027-r0tl01kq	1195	24	compared	compare	VBN
cord-010027-r0tl01kq	1195	25	to	to	IN
cord-010027-r0tl01kq	1195	26	the	the	DT
cord-010027-r0tl01kq	1195	27	control	control	NN
cord-010027-r0tl01kq	1195	28	.	.	.
cord-010027-r0tl01kq	1196	1	However	however	RB
cord-010027-r0tl01kq	1196	2	,	,	,
cord-010027-r0tl01kq	1196	3	knockdown	knockdown	NN
cord-010027-r0tl01kq	1196	4	of	of	IN
cord-010027-r0tl01kq	1196	5	CD40	CD40	NNP
cord-010027-r0tl01kq	1196	6	in	in	IN
cord-010027-r0tl01kq	1196	7	HCT116	HCT116	NNP
cord-010027-r0tl01kq	1196	8	did	do	VBD
cord-010027-r0tl01kq	1196	9	not	not	RB
cord-010027-r0tl01kq	1196	10	have	have	VB
cord-010027-r0tl01kq	1196	11	an	an	DT
cord-010027-r0tl01kq	1196	12	effect	effect	NN
cord-010027-r0tl01kq	1196	13	on	on	IN
cord-010027-r0tl01kq	1196	14	cell	cell	NN
cord-010027-r0tl01kq	1196	15	motility	motility	NN
cord-010027-r0tl01kq	1196	16	in	in	IN
cord-010027-r0tl01kq	1196	17	both	both	CC
cord-010027-r0tl01kq	1196	18	the	the	DT
cord-010027-r0tl01kq	1196	19	transwell	transwell	NNP
cord-010027-r0tl01kq	1196	20	migration	migration	NN
cord-010027-r0tl01kq	1196	21	(	(	-LRB-
cord-010027-r0tl01kq	1196	22	HCT116=	hct116=	CD
cord-010027-r0tl01kq	1196	23	p=0.253	p=0.253	NNS
cord-010027-r0tl01kq	1196	24	)	)	-RRB-
cord-010027-r0tl01kq	1196	25	and	and	CC
cord-010027-r0tl01kq	1196	26	wound	wound	VB
cord-010027-r0tl01kq	1196	27	healing	healing	NN
cord-010027-r0tl01kq	1196	28	assays	assay	NNS
cord-010027-r0tl01kq	1196	29	.	.	.
cord-010027-r0tl01kq	1197	1	Discussion	discussion	NN
cord-010027-r0tl01kq	1197	2	:	:	:
cord-010027-r0tl01kq	1198	1	CD40	CD40	NNP
cord-010027-r0tl01kq	1198	2	exhibited	exhibit	VBD
cord-010027-r0tl01kq	1198	3	oncogenic	oncogenic	JJ
cord-010027-r0tl01kq	1198	4	activity	activity	NN
cord-010027-r0tl01kq	1198	5	in	in	IN
cord-010027-r0tl01kq	1198	6	CRC	CRC	NNP
cord-010027-r0tl01kq	1198	7	cell	cell	NN
cord-010027-r0tl01kq	1198	8	lines	line	NNS
cord-010027-r0tl01kq	1198	9	.	.	.
cord-010027-r0tl01kq	1199	1	CD40	CD40	NNP
cord-010027-r0tl01kq	1199	2	enhanced	enhanced	JJ
cord-010027-r0tl01kq	1199	3	cell	cell	NN
cord-010027-r0tl01kq	1199	4	proliferation	proliferation	NN
cord-010027-r0tl01kq	1199	5	but	but	CC
cord-010027-r0tl01kq	1199	6	not	not	RB
cord-010027-r0tl01kq	1199	7	cell	cell	NN
cord-010027-r0tl01kq	1199	8	motility	motility	NN
cord-010027-r0tl01kq	1199	9	in	in	IN
cord-010027-r0tl01kq	1199	10	CRC	CRC	NNP
cord-010027-r0tl01kq	1199	11	cell	cell	NN
cord-010027-r0tl01kq	1199	12	lines	line	NNS
cord-010027-r0tl01kq	1199	13	.	.	.
cord-010027-r0tl01kq	1200	1	The	the	DT
cord-010027-r0tl01kq	1200	2	expression	expression	NN
cord-010027-r0tl01kq	1200	3	of	of	IN
cord-010027-r0tl01kq	1200	4	CD45	CD45	NNP
cord-010027-r0tl01kq	1200	5	(	(	-LRB-
cord-010027-r0tl01kq	1200	6	Common	Common	NNP
cord-010027-r0tl01kq	1200	7	Leucocyte	Leucocyte	NNP
cord-010027-r0tl01kq	1200	8	Antigen	Antigen	NNP
cord-010027-r0tl01kq	1200	9	)	)	-RRB-
cord-010027-r0tl01kq	1200	10	and	and	CC
cord-010027-r0tl01kq	1200	11	cytokeratin	cytokeratin	NNP
cord-010027-r0tl01kq	1200	12	is	be	VBZ
cord-010027-r0tl01kq	1200	13	thought	think	VBN
cord-010027-r0tl01kq	1200	14	to	to	TO
cord-010027-r0tl01kq	1200	15	be	be	VB
cord-010027-r0tl01kq	1200	16	mutually	mutually	RB
cord-010027-r0tl01kq	1200	17	exclusive	exclusive	JJ
cord-010027-r0tl01kq	1200	18	with	with	IN
cord-010027-r0tl01kq	1200	19	CD45	CD45	NNP
cord-010027-r0tl01kq	1200	20	expression	expression	NN
cord-010027-r0tl01kq	1200	21	largely	largely	RB
cord-010027-r0tl01kq	1200	22	restricted	restrict	VBN
cord-010027-r0tl01kq	1200	23	to	to	IN
cord-010027-r0tl01kq	1200	24	haematological	haematological	JJ
cord-010027-r0tl01kq	1200	25	malignancies	malignancy	NNS
cord-010027-r0tl01kq	1200	26	and	and	CC
cord-010027-r0tl01kq	1200	27	cytokeratin	cytokeratin	NNP
cord-010027-r0tl01kq	1200	28	expression	expression	NN
cord-010027-r0tl01kq	1200	29	largely	largely	RB
cord-010027-r0tl01kq	1200	30	restricted	restrict	VBN
cord-010027-r0tl01kq	1200	31	to	to	IN
cord-010027-r0tl01kq	1200	32	carcinomas	carcinoma	NNS
cord-010027-r0tl01kq	1200	33	.	.	.
cord-010027-r0tl01kq	1201	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1201	2	report	report	VBP
cord-010027-r0tl01kq	1201	3	two	two	CD
cord-010027-r0tl01kq	1201	4	clinically	clinically	RB
cord-010027-r0tl01kq	1201	5	relevant	relevant	JJ
cord-010027-r0tl01kq	1201	6	cases	case	NNS
cord-010027-r0tl01kq	1201	7	.	.	.
cord-010027-r0tl01kq	1202	1	The	the	DT
cord-010027-r0tl01kq	1202	2	first	first	JJ
cord-010027-r0tl01kq	1202	3	case	case	NN
cord-010027-r0tl01kq	1202	4	is	be	VBZ
cord-010027-r0tl01kq	1202	5	a	a	DT
cord-010027-r0tl01kq	1202	6	urinary	urinary	JJ
cord-010027-r0tl01kq	1202	7	bladder	bladder	NN
cord-010027-r0tl01kq	1202	8	biopsy	biopsy	NN
cord-010027-r0tl01kq	1202	9	showing	show	VBG
cord-010027-r0tl01kq	1202	10	a	a	DT
cord-010027-r0tl01kq	1202	11	high	high	JJ
cord-010027-r0tl01kq	1202	12	grade	grade	NN
cord-010027-r0tl01kq	1202	13	malignant	malignant	JJ
cord-010027-r0tl01kq	1202	14	tumour	tumour	NN
cord-010027-r0tl01kq	1202	15	with	with	IN
cord-010027-r0tl01kq	1202	16	cells	cell	NNS
cord-010027-r0tl01kq	1202	17	that	that	WDT
cord-010027-r0tl01kq	1202	18	had	have	VBD
cord-010027-r0tl01kq	1202	19	scanty	scanty	JJ
cord-010027-r0tl01kq	1202	20	cytoplasm	cytoplasm	NN
cord-010027-r0tl01kq	1202	21	,	,	,
cord-010027-r0tl01kq	1202	22	hyperchromatic	hyperchromatic	JJ
cord-010027-r0tl01kq	1202	23	stippled	stippled	JJ
cord-010027-r0tl01kq	1202	24	nuclei	nucleus	NNS
cord-010027-r0tl01kq	1202	25	and	and	CC
cord-010027-r0tl01kq	1202	26	high	high	JJ
cord-010027-r0tl01kq	1202	27	mitotic	mitotic	JJ
cord-010027-r0tl01kq	1202	28	activity	activity	NN
cord-010027-r0tl01kq	1202	29	.	.	.
cord-010027-r0tl01kq	1203	1	Nuclear	nuclear	JJ
cord-010027-r0tl01kq	1203	2	molding	molding	NN
cord-010027-r0tl01kq	1203	3	was	be	VBD
cord-010027-r0tl01kq	1203	4	present	present	JJ
cord-010027-r0tl01kq	1203	5	.	.	.
cord-010027-r0tl01kq	1204	1	The	the	DT
cord-010027-r0tl01kq	1204	2	tumour	tumour	NN
cord-010027-r0tl01kq	1204	3	cells	cell	NNS
cord-010027-r0tl01kq	1204	4	showed	show	VBD
cord-010027-r0tl01kq	1204	5	focal	focal	JJ
cord-010027-r0tl01kq	1204	6	strong	strong	JJ
cord-010027-r0tl01kq	1204	7	positivity	positivity	NN
cord-010027-r0tl01kq	1204	8	for	for	IN
cord-010027-r0tl01kq	1204	9	CK7	CK7	NNP
cord-010027-r0tl01kq	1204	10	and	and	CC
cord-010027-r0tl01kq	1204	11	diffuse	diffuse	VB
cord-010027-r0tl01kq	1204	12	positivity	positivity	NN
cord-010027-r0tl01kq	1204	13	for	for	IN
cord-010027-r0tl01kq	1204	14	CD56	CD56	NNP
cord-010027-r0tl01kq	1204	15	and	and	CC
cord-010027-r0tl01kq	1204	16	synaptophysin	synaptophysin	NNS
cord-010027-r0tl01kq	1204	17	.	.	.
cord-010027-r0tl01kq	1205	1	Focal	focal	JJ
cord-010027-r0tl01kq	1205	2	positivity	positivity	NN
cord-010027-r0tl01kq	1205	3	for	for	IN
cord-010027-r0tl01kq	1205	4	CD45	CD45	NNP
cord-010027-r0tl01kq	1205	5	was	be	VBD
cord-010027-r0tl01kq	1205	6	present	present	JJ
cord-010027-r0tl01kq	1205	7	and	and	CC
cord-010027-r0tl01kq	1205	8	confirmed	confirm	VBN
cord-010027-r0tl01kq	1205	9	on	on	IN
cord-010027-r0tl01kq	1205	10	repeat	repeat	NN
cord-010027-r0tl01kq	1205	11	staining	staining	NN
cord-010027-r0tl01kq	1205	12	.	.	.
cord-010027-r0tl01kq	1206	1	The	the	DT
cord-010027-r0tl01kq	1206	2	morphology	morphology	NN
cord-010027-r0tl01kq	1206	3	and	and	CC
cord-010027-r0tl01kq	1206	4	immunoprofile	immunoprofile	NN
cord-010027-r0tl01kq	1206	5	was	be	VBD
cord-010027-r0tl01kq	1206	6	consistent	consistent	JJ
cord-010027-r0tl01kq	1206	7	with	with	IN
cord-010027-r0tl01kq	1206	8	a	a	DT
cord-010027-r0tl01kq	1206	9	small	small	JJ
cord-010027-r0tl01kq	1206	10	cell	cell	NN
cord-010027-r0tl01kq	1206	11	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1206	12	showing	show	VBG
cord-010027-r0tl01kq	1206	13	aberrant	aberrant	JJ
cord-010027-r0tl01kq	1206	14	CD45	CD45	NNP
cord-010027-r0tl01kq	1206	15	expression	expression	NN
cord-010027-r0tl01kq	1206	16	.	.	.
cord-010027-r0tl01kq	1207	1	The	the	DT
cord-010027-r0tl01kq	1207	2	second	second	JJ
cord-010027-r0tl01kq	1207	3	case	case	NN
cord-010027-r0tl01kq	1207	4	is	be	VBZ
cord-010027-r0tl01kq	1207	5	a	a	DT
cord-010027-r0tl01kq	1207	6	maxillary	maxillary	JJ
cord-010027-r0tl01kq	1207	7	tumour	tumour	NN
cord-010027-r0tl01kq	1207	8	biopsy	biopsy	NN
cord-010027-r0tl01kq	1207	9	composed	compose	VBN
cord-010027-r0tl01kq	1207	10	of	of	IN
cord-010027-r0tl01kq	1207	11	medium	medium	JJ
cord-010027-r0tl01kq	1207	12	/	/	SYM
cord-010027-r0tl01kq	1207	13	large	large	JJ
cord-010027-r0tl01kq	1207	14	atypical	atypical	JJ
cord-010027-r0tl01kq	1207	15	lymphoid	lymphoid	JJ
cord-010027-r0tl01kq	1207	16	cells	cell	NNS
cord-010027-r0tl01kq	1207	17	with	with	IN
cord-010027-r0tl01kq	1207	18	hyperchromatic	hyperchromatic	JJ
cord-010027-r0tl01kq	1207	19	nuclei	nucleus	NNS
cord-010027-r0tl01kq	1207	20	,	,	,
cord-010027-r0tl01kq	1207	21	small	small	JJ
cord-010027-r0tl01kq	1207	22	nucleoli	nucleolus	NNS
cord-010027-r0tl01kq	1207	23	and	and	CC
cord-010027-r0tl01kq	1207	24	scanty	scanty	JJ
cord-010027-r0tl01kq	1207	25	cytoplasm	cytoplasm	NN
cord-010027-r0tl01kq	1207	26	.	.	.
cord-010027-r0tl01kq	1208	1	Mitoses	mitose	NNS
cord-010027-r0tl01kq	1208	2	and	and	CC
cord-010027-r0tl01kq	1208	3	apoptotic	apoptotic	JJ
cord-010027-r0tl01kq	1208	4	cells	cell	NNS
cord-010027-r0tl01kq	1208	5	were	be	VBD
cord-010027-r0tl01kq	1208	6	noted	note	VBN
cord-010027-r0tl01kq	1208	7	.	.	.
cord-010027-r0tl01kq	1209	1	Immunohistochemistry	Immunohistochemistry	NNP
cord-010027-r0tl01kq	1209	2	showed	show	VBD
cord-010027-r0tl01kq	1209	3	the	the	DT
cord-010027-r0tl01kq	1209	4	atypical	atypical	JJ
cord-010027-r0tl01kq	1209	5	cells	cell	NNS
cord-010027-r0tl01kq	1209	6	to	to	TO
cord-010027-r0tl01kq	1209	7	express	express	VB
cord-010027-r0tl01kq	1209	8	CD20	CD20	NNP
cord-010027-r0tl01kq	1209	9	,	,	,
cord-010027-r0tl01kq	1209	10	CD79a	CD79a	NNP
cord-010027-r0tl01kq	1209	11	,	,	,
cord-010027-r0tl01kq	1209	12	Bcl6	Bcl6	NNP
cord-010027-r0tl01kq	1209	13	and	and	CC
cord-010027-r0tl01kq	1209	14	MUM1	MUM1	NNP
cord-010027-r0tl01kq	1209	15	but	but	CC
cord-010027-r0tl01kq	1209	16	not	not	RB
cord-010027-r0tl01kq	1209	17	CD45	CD45	NNP
cord-010027-r0tl01kq	1209	18	,	,	,
cord-010027-r0tl01kq	1209	19	CD5	CD5	NNP
cord-010027-r0tl01kq	1209	20	,	,	,
cord-010027-r0tl01kq	1209	21	CD10	CD10	NNP
cord-010027-r0tl01kq	1209	22	,	,	,
cord-010027-r0tl01kq	1209	23	cyclin	cyclin	NN
cord-010027-r0tl01kq	1209	24	D1	d1	NN
cord-010027-r0tl01kq	1209	25	,	,	,
cord-010027-r0tl01kq	1209	26	CD30	CD30	NNP
cord-010027-r0tl01kq	1209	27	,	,	,
cord-010027-r0tl01kq	1209	28	TdT	tdt	NN
cord-010027-r0tl01kq	1209	29	,	,	,
cord-010027-r0tl01kq	1209	30	ALK1	ALK1	NNP
cord-010027-r0tl01kq	1209	31	,	,	,
cord-010027-r0tl01kq	1209	32	CD2	CD2	NNP
cord-010027-r0tl01kq	1209	33	,	,	,
cord-010027-r0tl01kq	1209	34	CD3	CD3	NNP
cord-010027-r0tl01kq	1209	35	,	,	,
cord-010027-r0tl01kq	1209	36	neuroendocrine	neuroendocrine	JJ
cord-010027-r0tl01kq	1209	37	or	or	CC
cord-010027-r0tl01kq	1209	38	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	1209	39	markers	marker	NNS
cord-010027-r0tl01kq	1209	40	.	.	.
cord-010027-r0tl01kq	1210	1	A	a	DT
cord-010027-r0tl01kq	1210	2	high	high	JJ
cord-010027-r0tl01kq	1210	3	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1210	4	proliferation	proliferation	NN
cord-010027-r0tl01kq	1210	5	fraction	fraction	NN
cord-010027-r0tl01kq	1210	6	was	be	VBD
cord-010027-r0tl01kq	1210	7	present	present	JJ
cord-010027-r0tl01kq	1210	8	.	.	.
cord-010027-r0tl01kq	1211	1	The	the	DT
cord-010027-r0tl01kq	1211	2	appearances	appearance	NNS
cord-010027-r0tl01kq	1211	3	were	be	VBD
cord-010027-r0tl01kq	1211	4	consistent	consistent	JJ
cord-010027-r0tl01kq	1211	5	with	with	IN
cord-010027-r0tl01kq	1211	6	a	a	DT
cord-010027-r0tl01kq	1211	7	diffuse	diffuse	JJ
cord-010027-r0tl01kq	1211	8	large	large	JJ
cord-010027-r0tl01kq	1211	9	B	b	NN
cord-010027-r0tl01kq	1211	10	-	-	HYPH
cord-010027-r0tl01kq	1211	11	cell	cell	NN
cord-010027-r0tl01kq	1211	12	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1211	13	.	.	.
cord-010027-r0tl01kq	1212	1	The	the	DT
cord-010027-r0tl01kq	1212	2	above	above	JJ
cord-010027-r0tl01kq	1212	3	cases	case	NNS
cord-010027-r0tl01kq	1212	4	highlight	highlight	VBP
cord-010027-r0tl01kq	1212	5	the	the	DT
cord-010027-r0tl01kq	1212	6	possibility	possibility	NN
cord-010027-r0tl01kq	1212	7	of	of	IN
cord-010027-r0tl01kq	1212	8	aberrant	aberrant	JJ
cord-010027-r0tl01kq	1212	9	expression	expression	NN
cord-010027-r0tl01kq	1212	10	as	as	RB
cord-010027-r0tl01kq	1212	11	well	well	RB
cord-010027-r0tl01kq	1212	12	as	as	IN
cord-010027-r0tl01kq	1212	13	loss	loss	NN
cord-010027-r0tl01kq	1212	14	of	of	IN
cord-010027-r0tl01kq	1212	15	expression	expression	NN
cord-010027-r0tl01kq	1212	16	of	of	IN
cord-010027-r0tl01kq	1212	17	immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	1212	18	markers	marker	NNS
cord-010027-r0tl01kq	1212	19	by	by	IN
cord-010027-r0tl01kq	1212	20	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	1212	21	cells	cell	NNS
cord-010027-r0tl01kq	1212	22	in	in	IN
cord-010027-r0tl01kq	1212	23	undifferentiated	undifferentiated	JJ
cord-010027-r0tl01kq	1212	24	malignancies	malignancy	NNS
cord-010027-r0tl01kq	1212	25	.	.	.
cord-010027-r0tl01kq	1213	1	Attention	attention	NN
cord-010027-r0tl01kq	1213	2	to	to	IN
cord-010027-r0tl01kq	1213	3	tumour	tumour	NN
cord-010027-r0tl01kq	1213	4	morphology	morphology	NN
cord-010027-r0tl01kq	1213	5	may	may	MD
cord-010027-r0tl01kq	1213	6	provide	provide	VB
cord-010027-r0tl01kq	1213	7	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1213	8	clues	clue	NNS
cord-010027-r0tl01kq	1213	9	.	.	.
cord-010027-r0tl01kq	1214	1	Interpretation	interpretation	NN
cord-010027-r0tl01kq	1214	2	of	of	IN
cord-010027-r0tl01kq	1214	3	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1214	4	in	in	IN
cord-010027-r0tl01kq	1214	5	the	the	DT
cord-010027-r0tl01kq	1214	6	context	context	NN
cord-010027-r0tl01kq	1214	7	of	of	IN
cord-010027-r0tl01kq	1214	8	tumour	tumour	NN
cord-010027-r0tl01kq	1214	9	morphology	morphology	NN
cord-010027-r0tl01kq	1214	10	as	as	RB
cord-010027-r0tl01kq	1214	11	well	well	RB
cord-010027-r0tl01kq	1214	12	as	as	IN
cord-010027-r0tl01kq	1214	13	awareness	awareness	NN
cord-010027-r0tl01kq	1214	14	of	of	IN
cord-010027-r0tl01kq	1214	15	aberrant	aberrant	JJ
cord-010027-r0tl01kq	1214	16	expression	expression	NN
cord-010027-r0tl01kq	1214	17	/	/	SYM
cord-010027-r0tl01kq	1214	18	loss	loss	NN
cord-010027-r0tl01kq	1214	19	of	of	IN
cord-010027-r0tl01kq	1214	20	expression	expression	NN
cord-010027-r0tl01kq	1214	21	can	can	MD
cord-010027-r0tl01kq	1214	22	help	help	VB
cord-010027-r0tl01kq	1214	23	avoid	avoid	VB
cord-010027-r0tl01kq	1214	24	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1214	25	error	error	NN
cord-010027-r0tl01kq	1214	26	.	.	.
cord-010027-r0tl01kq	1215	1	Accurate	accurate	JJ
cord-010027-r0tl01kq	1215	2	,	,	,
cord-010027-r0tl01kq	1215	3	timely	timely	JJ
cord-010027-r0tl01kq	1215	4	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1215	5	is	be	VBZ
cord-010027-r0tl01kq	1215	6	the	the	DT
cord-010027-r0tl01kq	1215	7	ultimate	ultimate	JJ
cord-010027-r0tl01kq	1215	8	aim	aim	NN
cord-010027-r0tl01kq	1215	9	in	in	IN
cord-010027-r0tl01kq	1215	10	surgical	surgical	JJ
cord-010027-r0tl01kq	1215	11	pathology	pathology	NN
cord-010027-r0tl01kq	1215	12	.	.	.
cord-010027-r0tl01kq	1216	1	Numerous	numerous	JJ
cord-010027-r0tl01kq	1216	2	histological	histological	JJ
cord-010027-r0tl01kq	1216	3	pitfalls	pitfall	NNS
cord-010027-r0tl01kq	1216	4	and	and	CC
cord-010027-r0tl01kq	1216	5	lesional	lesional	JJ
cord-010027-r0tl01kq	1216	6	mimics	mimic	NNS
cord-010027-r0tl01kq	1216	7	exist	exist	VBP
cord-010027-r0tl01kq	1216	8	,	,	,
cord-010027-r0tl01kq	1216	9	with	with	IN
cord-010027-r0tl01kq	1216	10	the	the	DT
cord-010027-r0tl01kq	1216	11	need	need	NN
cord-010027-r0tl01kq	1216	12	to	to	TO
cord-010027-r0tl01kq	1216	13	maintain	maintain	VB
cord-010027-r0tl01kq	1216	14	an	an	DT
cord-010027-r0tl01kq	1216	15	awareness	awareness	NN
cord-010027-r0tl01kq	1216	16	of	of	IN
cord-010027-r0tl01kq	1216	17	such	such	JJ
cord-010027-r0tl01kq	1216	18	entities	entity	NNS
cord-010027-r0tl01kq	1216	19	vital	vital	JJ
cord-010027-r0tl01kq	1216	20	if	if	IN
cord-010027-r0tl01kq	1216	21	potentially	potentially	RB
cord-010027-r0tl01kq	1216	22	serious	serious	JJ
cord-010027-r0tl01kq	1216	23	misdiagnoses	misdiagnose	NNS
cord-010027-r0tl01kq	1216	24	are	be	VBP
cord-010027-r0tl01kq	1216	25	to	to	TO
cord-010027-r0tl01kq	1216	26	be	be	VB
cord-010027-r0tl01kq	1216	27	avoided	avoid	VBN
cord-010027-r0tl01kq	1216	28	.	.	.
cord-010027-r0tl01kq	1217	1	This	this	DT
cord-010027-r0tl01kq	1217	2	case	case	NN
cord-010027-r0tl01kq	1217	3	report	report	NN
cord-010027-r0tl01kq	1217	4	describes	describe	VBZ
cord-010027-r0tl01kq	1217	5	two	two	CD
cord-010027-r0tl01kq	1217	6	distinct	distinct	JJ
cord-010027-r0tl01kq	1217	7	lesions	lesion	NNS
cord-010027-r0tl01kq	1217	8	within	within	IN
cord-010027-r0tl01kq	1217	9	the	the	DT
cord-010027-r0tl01kq	1217	10	same	same	JJ
cord-010027-r0tl01kq	1217	11	lymph	lymph	NN
cord-010027-r0tl01kq	1217	12	node	node	NN
cord-010027-r0tl01kq	1217	13	,	,	,
cord-010027-r0tl01kq	1217	14	both	both	DT
cord-010027-r0tl01kq	1217	15	of	of	IN
cord-010027-r0tl01kq	1217	16	which	which	WDT
cord-010027-r0tl01kq	1217	17	are	be	VBP
cord-010027-r0tl01kq	1217	18	potential	potential	JJ
cord-010027-r0tl01kq	1217	19	mimics	mimic	NNS
cord-010027-r0tl01kq	1217	20	of	of	IN
cord-010027-r0tl01kq	1217	21	each	each	DT
cord-010027-r0tl01kq	1217	22	other	other	JJ
cord-010027-r0tl01kq	1217	23	.	.	.
cord-010027-r0tl01kq	1218	1	A	a	DT
cord-010027-r0tl01kq	1218	2	43	43	CD
cord-010027-r0tl01kq	1218	3	year	year	NN
cord-010027-r0tl01kq	1218	4	old	old	JJ
cord-010027-r0tl01kq	1218	5	female	female	NN
cord-010027-r0tl01kq	1218	6	presented	present	VBN
cord-010027-r0tl01kq	1218	7	with	with	IN
cord-010027-r0tl01kq	1218	8	a	a	DT
cord-010027-r0tl01kq	1218	9	three	three	CD
cord-010027-r0tl01kq	1218	10	week	week	NN
cord-010027-r0tl01kq	1218	11	history	history	NN
cord-010027-r0tl01kq	1218	12	of	of	IN
cord-010027-r0tl01kq	1218	13	a	a	DT
cord-010027-r0tl01kq	1218	14	left	left	JJ
cord-010027-r0tl01kq	1218	15	breast	breast	NN
cord-010027-r0tl01kq	1218	16	lump	lump	NN
cord-010027-r0tl01kq	1218	17	.	.	.
cord-010027-r0tl01kq	1219	1	She	-PRON-	PRP
cord-010027-r0tl01kq	1219	2	had	have	VBD
cord-010027-r0tl01kq	1219	3	no	no	DT
cord-010027-r0tl01kq	1219	4	known	know	VBN
cord-010027-r0tl01kq	1219	5	previous	previous	JJ
cord-010027-r0tl01kq	1219	6	breast	breast	NN
cord-010027-r0tl01kq	1219	7	disease	disease	NN
cord-010027-r0tl01kq	1219	8	or	or	CC
cord-010027-r0tl01kq	1219	9	any	any	DT
cord-010027-r0tl01kq	1219	10	associated	associated	JJ
cord-010027-r0tl01kq	1219	11	risk	risk	NN
cord-010027-r0tl01kq	1219	12	factors	factor	NNS
cord-010027-r0tl01kq	1219	13	.	.	.
cord-010027-r0tl01kq	1220	1	A	a	DT
cord-010027-r0tl01kq	1220	2	needle	needle	NN
cord-010027-r0tl01kq	1220	3	core	core	NN
cord-010027-r0tl01kq	1220	4	biopsy	biopsy	NN
cord-010027-r0tl01kq	1220	5	of	of	IN
cord-010027-r0tl01kq	1220	6	this	this	DT
cord-010027-r0tl01kq	1220	7	clinically	clinically	RB
cord-010027-r0tl01kq	1220	8	and	and	CC
cord-010027-r0tl01kq	1220	9	radiologically	radiologically	RB
cord-010027-r0tl01kq	1220	10	suspicious	suspicious	JJ
cord-010027-r0tl01kq	1220	11	mass	mass	NN
cord-010027-r0tl01kq	1220	12	yielded	yield	VBD
cord-010027-r0tl01kq	1220	13	a	a	DT
cord-010027-r0tl01kq	1220	14	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1220	15	of	of	IN
cord-010027-r0tl01kq	1220	16	grade	grade	NN
cord-010027-r0tl01kq	1220	17	2	2	CD
cord-010027-r0tl01kq	1220	18	invasive	invasive	JJ
cord-010027-r0tl01kq	1220	19	lobular	lobular	JJ
cord-010027-r0tl01kq	1220	20	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1220	21	.	.	.
cord-010027-r0tl01kq	1221	1	Left	leave	VBN
cord-010027-r0tl01kq	1221	2	axillary	axillary	JJ
cord-010027-r0tl01kq	1221	3	sentinel	sentinel	NN
cord-010027-r0tl01kq	1221	4	node	node	NN
cord-010027-r0tl01kq	1221	5	biopsy	biopsy	NNP
cord-010027-r0tl01kq	1221	6	was	be	VBD
cord-010027-r0tl01kq	1221	7	thus	thus	RB
cord-010027-r0tl01kq	1221	8	undertaken	undertake	VBN
cord-010027-r0tl01kq	1221	9	.	.	.
cord-010027-r0tl01kq	1222	1	Two	two	CD
cord-010027-r0tl01kq	1222	2	hot	hot	JJ
cord-010027-r0tl01kq	1222	3	and	and	CC
cord-010027-r0tl01kq	1222	4	blue	blue	JJ
cord-010027-r0tl01kq	1222	5	sentinel	sentinel	JJ
cord-010027-r0tl01kq	1222	6	lymph	lymph	NN
cord-010027-r0tl01kq	1222	7	nodes	node	NNS
cord-010027-r0tl01kq	1222	8	were	be	VBD
cord-010027-r0tl01kq	1222	9	excised	excise	VBN
cord-010027-r0tl01kq	1222	10	.	.	.
cord-010027-r0tl01kq	1223	1	One	one	CD
cord-010027-r0tl01kq	1223	2	was	be	VBD
cord-010027-r0tl01kq	1223	3	free	free	JJ
cord-010027-r0tl01kq	1223	4	of	of	IN
cord-010027-r0tl01kq	1223	5	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	1223	6	,	,	,
cord-010027-r0tl01kq	1223	7	the	the	DT
cord-010027-r0tl01kq	1223	8	second	second	NN
cord-010027-r0tl01kq	1223	9	contained	contain	VBD
cord-010027-r0tl01kq	1223	10	benign	benign	JJ
cord-010027-r0tl01kq	1223	11	naevus	naevus	NN
cord-010027-r0tl01kq	1223	12	cell	cell	NN
cord-010027-r0tl01kq	1223	13	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1223	14	within	within	IN
cord-010027-r0tl01kq	1223	15	the	the	DT
cord-010027-r0tl01kq	1223	16	capsule	capsule	NN
cord-010027-r0tl01kq	1223	17	together	together	RB
cord-010027-r0tl01kq	1223	18	with	with	IN
cord-010027-r0tl01kq	1223	19	a	a	DT
cord-010027-r0tl01kq	1223	20	micrometastasis	micrometastasis	NN
cord-010027-r0tl01kq	1223	21	.	.	.
cord-010027-r0tl01kq	1224	1	Immunocytochemistry	Immunocytochemistry	NNP
cord-010027-r0tl01kq	1224	2	confirmed	confirm	VBD
cord-010027-r0tl01kq	1224	3	the	the	DT
cord-010027-r0tl01kq	1224	4	presence	presence	NN
cord-010027-r0tl01kq	1224	5	of	of	IN
cord-010027-r0tl01kq	1224	6	two	two	CD
cord-010027-r0tl01kq	1224	7	distinct	distinct	JJ
cord-010027-r0tl01kq	1224	8	cell	cell	NN
cord-010027-r0tl01kq	1224	9	populations	population	NNS
cord-010027-r0tl01kq	1224	10	;	;	:
cord-010027-r0tl01kq	1224	11	the	the	DT
cord-010027-r0tl01kq	1224	12	benign	benign	JJ
cord-010027-r0tl01kq	1224	13	naevus	naevus	NN
cord-010027-r0tl01kq	1224	14	inclusion	inclusion	NN
cord-010027-r0tl01kq	1224	15	cells	cell	NNS
cord-010027-r0tl01kq	1224	16	stained	stain	VBN
cord-010027-r0tl01kq	1224	17	positively	positively	RB
cord-010027-r0tl01kq	1224	18	for	for	IN
cord-010027-r0tl01kq	1224	19	S100	S100	NNP
cord-010027-r0tl01kq	1225	1	but	but	CC
cord-010027-r0tl01kq	1225	2	not	not	RB
cord-010027-r0tl01kq	1225	3	for	for	IN
cord-010027-r0tl01kq	1226	1	AE1/3	AE1/3	NNP
cord-010027-r0tl01kq	1226	2	,	,	,
cord-010027-r0tl01kq	1226	3	the	the	DT
cord-010027-r0tl01kq	1226	4	reverse	reverse	JJ
cord-010027-r0tl01kq	1226	5	pattern	pattern	NN
cord-010027-r0tl01kq	1226	6	was	be	VBD
cord-010027-r0tl01kq	1226	7	observed	observe	VBN
cord-010027-r0tl01kq	1226	8	in	in	IN
cord-010027-r0tl01kq	1226	9	the	the	DT
cord-010027-r0tl01kq	1226	10	invasive	invasive	JJ
cord-010027-r0tl01kq	1226	11	lobular	lobular	JJ
cord-010027-r0tl01kq	1226	12	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1226	13	cells	cell	NNS
cord-010027-r0tl01kq	1226	14	.	.	.
cord-010027-r0tl01kq	1227	1	Heterotrophic	heterotrophic	JJ
cord-010027-r0tl01kq	1227	2	benign	benign	JJ
cord-010027-r0tl01kq	1227	3	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1227	4	within	within	IN
cord-010027-r0tl01kq	1227	5	lymph	lymph	NN
cord-010027-r0tl01kq	1227	6	nodes	node	NNS
cord-010027-r0tl01kq	1227	7	are	be	VBP
cord-010027-r0tl01kq	1227	8	an	an	DT
cord-010027-r0tl01kq	1227	9	infrequent	infrequent	JJ
cord-010027-r0tl01kq	1227	10	yet	yet	RB
cord-010027-r0tl01kq	1227	11	well	well	RB
cord-010027-r0tl01kq	1227	12	recognised	recognise	VBN
cord-010027-r0tl01kq	1227	13	entity	entity	NN
cord-010027-r0tl01kq	1227	14	.	.	.
cord-010027-r0tl01kq	1228	1	Ridolfi	Ridolfi	NNP
cord-010027-r0tl01kq	1228	2	et	et	NNP
cord-010027-r0tl01kq	1228	3	al	al	NNP
cord-010027-r0tl01kq	1228	4	reviewed	review	VBD
cord-010027-r0tl01kq	1228	5	the	the	DT
cord-010027-r0tl01kq	1228	6	lymph	lymph	NN
cord-010027-r0tl01kq	1228	7	nodes	node	NNS
cord-010027-r0tl01kq	1228	8	from	from	IN
cord-010027-r0tl01kq	1228	9	909	909	CD
cord-010027-r0tl01kq	1228	10	axillary	axillary	JJ
cord-010027-r0tl01kq	1228	11	surgery	surgery	NN
cord-010027-r0tl01kq	1228	12	patients	patient	NNS
cord-010027-r0tl01kq	1228	13	and	and	CC
cord-010027-r0tl01kq	1228	14	found	find	VBD
cord-010027-r0tl01kq	1228	15	0.017	0.017	CD
cord-010027-r0tl01kq	1228	16	%	%	NN
cord-010027-r0tl01kq	1228	17	of	of	IN
cord-010027-r0tl01kq	1228	18	lymph	lymph	NN
cord-010027-r0tl01kq	1228	19	nodes	node	NNS
cord-010027-r0tl01kq	1228	20	contained	contain	VBD
cord-010027-r0tl01kq	1228	21	benign	benign	JJ
cord-010027-r0tl01kq	1228	22	naevus	naevus	NN
cord-010027-r0tl01kq	1228	23	cell	cell	NN
cord-010027-r0tl01kq	1228	24	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1228	25	.	.	.
cord-010027-r0tl01kq	1229	1	Small	small	JJ
cord-010027-r0tl01kq	1229	2	benign	benign	JJ
cord-010027-r0tl01kq	1229	3	naevus	naevus	NN
cord-010027-r0tl01kq	1229	4	cells	cell	NNS
cord-010027-r0tl01kq	1229	5	within	within	IN
cord-010027-r0tl01kq	1229	6	the	the	DT
cord-010027-r0tl01kq	1229	7	capsule	capsule	NN
cord-010027-r0tl01kq	1229	8	of	of	IN
cord-010027-r0tl01kq	1229	9	a	a	DT
cord-010027-r0tl01kq	1229	10	lymph	lymph	NN
cord-010027-r0tl01kq	1229	11	node	node	NN
cord-010027-r0tl01kq	1229	12	can	can	MD
cord-010027-r0tl01kq	1229	13	resemble	resemble	VB
cord-010027-r0tl01kq	1229	14	the	the	DT
cord-010027-r0tl01kq	1229	15	'	'	``
cord-010027-r0tl01kq	1229	16	Indian	indian	JJ
cord-010027-r0tl01kq	1229	17	file	file	NN
cord-010027-r0tl01kq	1229	18	'	'	''
cord-010027-r0tl01kq	1229	19	pattern	pattern	NN
cord-010027-r0tl01kq	1229	20	of	of	IN
cord-010027-r0tl01kq	1229	21	classic	classic	JJ
cord-010027-r0tl01kq	1229	22	invasive	invasive	JJ
cord-010027-r0tl01kq	1229	23	lobular	lobular	JJ
cord-010027-r0tl01kq	1229	24	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1229	25	.	.	.
cord-010027-r0tl01kq	1230	1	This	this	DT
cord-010027-r0tl01kq	1230	2	case	case	NN
cord-010027-r0tl01kq	1230	3	is	be	VBZ
cord-010027-r0tl01kq	1230	4	unusual	unusual	JJ
cord-010027-r0tl01kq	1230	5	in	in	IN
cord-010027-r0tl01kq	1230	6	that	that	IN
cord-010027-r0tl01kq	1230	7	both	both	DT
cord-010027-r0tl01kq	1230	8	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1230	9	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1230	10	and	and	CC
cord-010027-r0tl01kq	1230	11	benign	benign	JJ
cord-010027-r0tl01kq	1230	12	naevus	naevus	NN
cord-010027-r0tl01kq	1230	13	inclusion	inclusion	NN
cord-010027-r0tl01kq	1230	14	cells	cell	NNS
cord-010027-r0tl01kq	1230	15	were	be	VBD
cord-010027-r0tl01kq	1230	16	present	present	JJ
cord-010027-r0tl01kq	1230	17	within	within	IN
cord-010027-r0tl01kq	1230	18	the	the	DT
cord-010027-r0tl01kq	1230	19	same	same	JJ
cord-010027-r0tl01kq	1230	20	lymph	lymph	NN
cord-010027-r0tl01kq	1230	21	node	node	NN
cord-010027-r0tl01kq	1230	22	,	,	,
cord-010027-r0tl01kq	1230	23	enabling	enable	VBG
cord-010027-r0tl01kq	1230	24	a	a	DT
cord-010027-r0tl01kq	1230	25	clear	clear	JJ
cord-010027-r0tl01kq	1230	26	comparison	comparison	NN
cord-010027-r0tl01kq	1230	27	of	of	IN
cord-010027-r0tl01kq	1230	28	the	the	DT
cord-010027-r0tl01kq	1230	29	cytomorphology	cytomorphology	NN
cord-010027-r0tl01kq	1230	30	and	and	CC
cord-010027-r0tl01kq	1230	31	immunoprofile	immunoprofile	NN
cord-010027-r0tl01kq	1230	32	of	of	IN
cord-010027-r0tl01kq	1230	33	these	these	DT
cord-010027-r0tl01kq	1230	34	two	two	CD
cord-010027-r0tl01kq	1230	35	distinct	distinct	JJ
cord-010027-r0tl01kq	1230	36	lesions	lesion	NNS
cord-010027-r0tl01kq	1230	37	.	.	.
cord-010027-r0tl01kq	1231	1	An	an	DT
cord-010027-r0tl01kq	1231	2	awareness	awareness	NN
cord-010027-r0tl01kq	1231	3	of	of	IN
cord-010027-r0tl01kq	1231	4	benign	benign	JJ
cord-010027-r0tl01kq	1231	5	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1231	6	within	within	IN
cord-010027-r0tl01kq	1231	7	lymph	lymph	NN
cord-010027-r0tl01kq	1231	8	nodes	node	NNS
cord-010027-r0tl01kq	1231	9	helps	help	VBZ
cord-010027-r0tl01kq	1231	10	to	to	TO
cord-010027-r0tl01kq	1231	11	avoid	avoid	VB
cord-010027-r0tl01kq	1231	12	the	the	DT
cord-010027-r0tl01kq	1231	13	potential	potential	NN
cord-010027-r0tl01kq	1231	14	for	for	IN
cord-010027-r0tl01kq	1231	15	misdiagnosis	misdiagnosis	NN
cord-010027-r0tl01kq	1231	16	.	.	.
cord-010027-r0tl01kq	1232	1	The	the	DT
cord-010027-r0tl01kq	1232	2	judicious	judicious	JJ
cord-010027-r0tl01kq	1232	3	use	use	NN
cord-010027-r0tl01kq	1232	4	of	of	IN
cord-010027-r0tl01kq	1232	5	immunocytochemistry	immunocytochemistry	NN
cord-010027-r0tl01kq	1232	6	can	can	MD
cord-010027-r0tl01kq	1232	7	be	be	VB
cord-010027-r0tl01kq	1232	8	useful	useful	JJ
cord-010027-r0tl01kq	1232	9	in	in	IN
cord-010027-r0tl01kq	1232	10	distinguishing	distinguish	VBG
cord-010027-r0tl01kq	1232	11	benign	benign	JJ
cord-010027-r0tl01kq	1232	12	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1232	13	from	from	IN
cord-010027-r0tl01kq	1232	14	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1232	15	.	.	.
cord-010027-r0tl01kq	1233	1	Recently	recently	RB
cord-010027-r0tl01kq	1233	2	there	there	EX
cord-010027-r0tl01kq	1233	3	has	have	VBZ
cord-010027-r0tl01kq	1233	4	been	be	VBN
cord-010027-r0tl01kq	1233	5	increasing	increase	VBG
cord-010027-r0tl01kq	1233	6	recognition	recognition	NN
cord-010027-r0tl01kq	1233	7	of	of	IN
cord-010027-r0tl01kq	1233	8	distinct	distinct	JJ
cord-010027-r0tl01kq	1233	9	breast	breast	NN
cord-010027-r0tl01kq	1233	10	cancer	cancer	NN
cord-010027-r0tl01kq	1233	11	phenotypes	phenotype	NNS
cord-010027-r0tl01kq	1233	12	.	.	.
cord-010027-r0tl01kq	1234	1	Of	of	IN
cord-010027-r0tl01kq	1234	2	these	these	DT
cord-010027-r0tl01kq	1234	3	,	,	,
cord-010027-r0tl01kq	1234	4	Basal	Basal	NNP
cord-010027-r0tl01kq	1234	5	phenotype	phenotype	NN
cord-010027-r0tl01kq	1234	6	breast	breast	NN
cord-010027-r0tl01kq	1234	7	cancer	cancer	NN
cord-010027-r0tl01kq	1234	8	(	(	-LRB-
cord-010027-r0tl01kq	1234	9	BBC	BBC	NNP
cord-010027-r0tl01kq	1234	10	)	)	-RRB-
cord-010027-r0tl01kq	1234	11	has	have	VBZ
cord-010027-r0tl01kq	1234	12	attracted	attract	VBN
cord-010027-r0tl01kq	1234	13	particular	particular	JJ
cord-010027-r0tl01kq	1234	14	interest	interest	NN
cord-010027-r0tl01kq	1234	15	since	since	IN
cord-010027-r0tl01kq	1234	16	the	the	DT
cord-010027-r0tl01kq	1234	17	majority	majority	NN
cord-010027-r0tl01kq	1234	18	are	be	VBP
cord-010027-r0tl01kq	1234	19	triple	triple	JJ
cord-010027-r0tl01kq	1234	20	negative	negative	JJ
cord-010027-r0tl01kq	1234	21	(	(	-LRB-
cord-010027-r0tl01kq	1234	22	TN	TN	NNP
cord-010027-r0tl01kq	1234	23	)	)	-RRB-
cord-010027-r0tl01kq	1234	24	;	;	:
cord-010027-r0tl01kq	1234	25	have	have	VBP
cord-010027-r0tl01kq	1234	26	an	an	DT
cord-010027-r0tl01kq	1234	27	aggressive	aggressive	JJ
cord-010027-r0tl01kq	1234	28	natural	natural	JJ
cord-010027-r0tl01kq	1234	29	history	history	NN
cord-010027-r0tl01kq	1234	30	and	and	CC
cord-010027-r0tl01kq	1234	31	can	can	MD
cord-010027-r0tl01kq	1234	32	be	be	VB
cord-010027-r0tl01kq	1234	33	associated	associate	VBN
cord-010027-r0tl01kq	1234	34	with	with	IN
cord-010027-r0tl01kq	1234	35	BRCA1	BRCA1	NNP
cord-010027-r0tl01kq	1234	36	germline	germline	NNP
cord-010027-r0tl01kq	1234	37	mutation	mutation	NN
cord-010027-r0tl01kq	1234	38	.	.	.
cord-010027-r0tl01kq	1235	1	This	this	DT
cord-010027-r0tl01kq	1235	2	area	area	NN
cord-010027-r0tl01kq	1235	3	is	be	VBZ
cord-010027-r0tl01kq	1235	4	mired	mire	VBN
cord-010027-r0tl01kq	1235	5	in	in	IN
cord-010027-r0tl01kq	1235	6	difficulty	difficulty	NN
cord-010027-r0tl01kq	1235	7	,	,	,
cord-010027-r0tl01kq	1235	8	as	as	IN
cord-010027-r0tl01kq	1235	9	a	a	DT
cord-010027-r0tl01kq	1235	10	precise	precise	JJ
cord-010027-r0tl01kq	1235	11	unifying	unifying	JJ
cord-010027-r0tl01kq	1235	12	definition	definition	NN
cord-010027-r0tl01kq	1235	13	of	of	IN
cord-010027-r0tl01kq	1235	14	BBC	BBC	NNP
cord-010027-r0tl01kq	1235	15	remains	remain	VBZ
cord-010027-r0tl01kq	1235	16	elusive	elusive	JJ
cord-010027-r0tl01kq	1235	17	.	.	.
cord-010027-r0tl01kq	1236	1	Several	several	JJ
cord-010027-r0tl01kq	1236	2	morphological	morphological	JJ
cord-010027-r0tl01kq	1236	3	features	feature	NNS
cord-010027-r0tl01kq	1236	4	more	more	RBR
cord-010027-r0tl01kq	1236	5	prevalent	prevalent	JJ
cord-010027-r0tl01kq	1236	6	in	in	IN
cord-010027-r0tl01kq	1236	7	BBC	BBC	NNP
cord-010027-r0tl01kq	1236	8	have	have	VBP
cord-010027-r0tl01kq	1236	9	been	be	VBN
cord-010027-r0tl01kq	1236	10	identified	identify	VBN
cord-010027-r0tl01kq	1236	11	.	.	.
cord-010027-r0tl01kq	1237	1	In	in	IN
cord-010027-r0tl01kq	1237	2	our	-PRON-	PRP$
cord-010027-r0tl01kq	1237	3	practise	practise	NN
cord-010027-r0tl01kq	1237	4	we	-PRON-	PRP
cord-010027-r0tl01kq	1237	5	noticed	notice	VBD
cord-010027-r0tl01kq	1237	6	variable	variable	JJ
cord-010027-r0tl01kq	1237	7	use	use	NN
cord-010027-r0tl01kq	1237	8	of	of	IN
cord-010027-r0tl01kq	1237	9	'	'	``
cord-010027-r0tl01kq	1237	10	basal	basal	NN
cord-010027-r0tl01kq	1237	11	'	'	''
cord-010027-r0tl01kq	1237	12	in	in	IN
cord-010027-r0tl01kq	1237	13	reports	report	NNS
cord-010027-r0tl01kq	1237	14	.	.	.
cord-010027-r0tl01kq	1238	1	Given	give	VBN
cord-010027-r0tl01kq	1238	2	this	this	DT
cord-010027-r0tl01kq	1238	3	,	,	,
cord-010027-r0tl01kq	1238	4	whilst	whilst	IN
cord-010027-r0tl01kq	1238	5	no	no	DT
cord-010027-r0tl01kq	1238	6	specific	specific	JJ
cord-010027-r0tl01kq	1238	7	therapies	therapy	NNS
cord-010027-r0tl01kq	1238	8	to	to	IN
cord-010027-r0tl01kq	1238	9	BBC	BBC	NNP
cord-010027-r0tl01kq	1238	10	currently	currently	RB
cord-010027-r0tl01kq	1238	11	exist	exist	VBP
cord-010027-r0tl01kq	1238	12	,	,	,
cord-010027-r0tl01kq	1238	13	we	-PRON-	PRP
cord-010027-r0tl01kq	1238	14	felt	feel	VBD
cord-010027-r0tl01kq	1238	15	it	-PRON-	PRP
cord-010027-r0tl01kq	1238	16	necessary	necessary	JJ
cord-010027-r0tl01kq	1238	17	to	to	TO
cord-010027-r0tl01kq	1238	18	understand	understand	VB
cord-010027-r0tl01kq	1238	19	how	how	WRB
cord-010027-r0tl01kq	1238	20	accurate	accurate	JJ
cord-010027-r0tl01kq	1238	21	our	-PRON-	PRP$
cord-010027-r0tl01kq	1238	22	designations	designation	NNS
cord-010027-r0tl01kq	1238	23	have	have	VBP
cord-010027-r0tl01kq	1238	24	been	be	VBN
cord-010027-r0tl01kq	1238	25	and	and	CC
cord-010027-r0tl01kq	1238	26	whether	whether	IN
cord-010027-r0tl01kq	1238	27	this	this	DT
cord-010027-r0tl01kq	1238	28	is	be	VBZ
cord-010027-r0tl01kq	1238	29	a	a	DT
cord-010027-r0tl01kq	1238	30	worthwhile	worthwhile	JJ
cord-010027-r0tl01kq	1238	31	practise	practise	NN
cord-010027-r0tl01kq	1238	32	.	.	.
cord-010027-r0tl01kq	1239	1	Method	method	NN
cord-010027-r0tl01kq	1239	2	:	:	:
cord-010027-r0tl01kq	1240	1	The	the	DT
cord-010027-r0tl01kq	1240	2	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1240	3	database	database	NN
cord-010027-r0tl01kq	1240	4	was	be	VBD
cord-010027-r0tl01kq	1240	5	searched	search	VBN
cord-010027-r0tl01kq	1240	6	for	for	IN
cord-010027-r0tl01kq	1240	7	all	all	DT
cord-010027-r0tl01kq	1240	8	malignant	malignant	JJ
cord-010027-r0tl01kq	1240	9	TN	TN	NNP
cord-010027-r0tl01kq	1240	10	breast	breast	NN
cord-010027-r0tl01kq	1240	11	resections	resection	NNS
cord-010027-r0tl01kq	1240	12	or	or	CC
cord-010027-r0tl01kq	1240	13	reports	report	NNS
cord-010027-r0tl01kq	1240	14	containing	contain	VBG
cord-010027-r0tl01kq	1240	15	the	the	DT
cord-010027-r0tl01kq	1240	16	word	word	NN
cord-010027-r0tl01kq	1240	17	'	'	``
cord-010027-r0tl01kq	1240	18	basal	basal	NN
cord-010027-r0tl01kq	1240	19	'	'	''
cord-010027-r0tl01kq	1240	20	within	within	IN
cord-010027-r0tl01kq	1240	21	12-months	12-month	NNS
cord-010027-r0tl01kq	1240	22	.	.	.
cord-010027-r0tl01kq	1241	1	TN	TN	NNP
cord-010027-r0tl01kq	1241	2	was	be	VBD
cord-010027-r0tl01kq	1241	3	defined	define	VBN
cord-010027-r0tl01kq	1241	4	as	as	IN
cord-010027-r0tl01kq	1241	5	Allred	Allred	NNP
cord-010027-r0tl01kq	1241	6	score	score	NN
cord-010027-r0tl01kq	1241	7	ER	ER	NNP
cord-010027-r0tl01kq	1241	8	0	0	CD
cord-010027-r0tl01kq	1241	9	-	-	HYPH
cord-010027-r0tl01kq	1241	10	2/8	2/8	CD
cord-010027-r0tl01kq	1241	11	,	,	,
cord-010027-r0tl01kq	1241	12	PR	PR	NNP
cord-010027-r0tl01kq	1241	13	0	0	CD
cord-010027-r0tl01kq	1241	14	-	-	HYPH
cord-010027-r0tl01kq	1241	15	2/8	2/8	CD
cord-010027-r0tl01kq	1241	16	and	and	CC
cord-010027-r0tl01kq	1241	17	HER2	HER2	NNP
cord-010027-r0tl01kq	1241	18	0	0	CD
cord-010027-r0tl01kq	1241	19	,	,	,
cord-010027-r0tl01kq	1241	20	1	1	CD
cord-010027-r0tl01kq	1241	21	+	+	SYM
cord-010027-r0tl01kq	1241	22	or	or	CC
cord-010027-r0tl01kq	1241	23	2	2	CD
cord-010027-r0tl01kq	1241	24	+	+	CC
cord-010027-r0tl01kq	1241	25	negative	negative	JJ
cord-010027-r0tl01kq	1241	26	on	on	IN
cord-010027-r0tl01kq	1241	27	FISH	fish	NN
cord-010027-r0tl01kq	1241	28	.	.	.
cord-010027-r0tl01kq	1242	1	For	for	IN
cord-010027-r0tl01kq	1242	2	completeness	completeness	NN
cord-010027-r0tl01kq	1242	3	,	,	,
cord-010027-r0tl01kq	1242	4	we	-PRON-	PRP
cord-010027-r0tl01kq	1242	5	considered	consider	VBD
cord-010027-r0tl01kq	1242	6	including	include	VBG
cord-010027-r0tl01kq	1242	7	all	all	DT
cord-010027-r0tl01kq	1242	8	breast	breast	NN
cord-010027-r0tl01kq	1242	9	cancers	cancer	NNS
cord-010027-r0tl01kq	1242	10	,	,	,
cord-010027-r0tl01kq	1242	11	but	but	CC
cord-010027-r0tl01kq	1242	12	pragmatically	pragmatically	RB
cord-010027-r0tl01kq	1242	13	this	this	DT
cord-010027-r0tl01kq	1242	14	was	be	VBD
cord-010027-r0tl01kq	1242	15	not	not	RB
cord-010027-r0tl01kq	1242	16	possible	possible	JJ
cord-010027-r0tl01kq	1242	17	.	.	.
cord-010027-r0tl01kq	1243	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1243	2	carried	carry	VBD
cord-010027-r0tl01kq	1243	3	out	out	RP
cord-010027-r0tl01kq	1243	4	CK5	ck5	NN
cord-010027-r0tl01kq	1243	5	and	and	CC
cord-010027-r0tl01kq	1243	6	CK14	CK14	NNP
cord-010027-r0tl01kq	1243	7	staining	stain	VBG
cord-010027-r0tl01kq	1243	8	on	on	IN
cord-010027-r0tl01kq	1243	9	all	all	DT
cord-010027-r0tl01kq	1243	10	cases	case	NNS
cord-010027-r0tl01kq	1243	11	where	where	WRB
cord-010027-r0tl01kq	1243	12	not	not	RB
cord-010027-r0tl01kq	1243	13	performed	perform	VBN
cord-010027-r0tl01kq	1243	14	.	.	.
cord-010027-r0tl01kq	1244	1	Results	result	NNS
cord-010027-r0tl01kq	1244	2	:	:	:
cord-010027-r0tl01kq	1245	1	Of	of	IN
cord-010027-r0tl01kq	1245	2	the	the	DT
cord-010027-r0tl01kq	1245	3	618	618	CD
cord-010027-r0tl01kq	1245	4	invasive	invasive	JJ
cord-010027-r0tl01kq	1245	5	breast	breast	NN
cord-010027-r0tl01kq	1245	6	cancers	cancer	NNS
cord-010027-r0tl01kq	1245	7	,	,	,
cord-010027-r0tl01kq	1245	8	69	69	CD
cord-010027-r0tl01kq	1245	9	cases	case	NNS
cord-010027-r0tl01kq	1245	10	(	(	-LRB-
cord-010027-r0tl01kq	1245	11	11	11	CD
cord-010027-r0tl01kq	1245	12	%	%	NN
cord-010027-r0tl01kq	1245	13	)	)	-RRB-
cord-010027-r0tl01kq	1245	14	were	be	VBD
cord-010027-r0tl01kq	1245	15	identified	identify	VBN
cord-010027-r0tl01kq	1245	16	,	,	,
cord-010027-r0tl01kq	1245	17	of	of	IN
cord-010027-r0tl01kq	1245	18	which	which	WDT
cord-010027-r0tl01kq	1245	19	88	88	CD
cord-010027-r0tl01kq	1245	20	%	%	NN
cord-010027-r0tl01kq	1245	21	were	be	VBD
cord-010027-r0tl01kq	1245	22	TN	TN	NNP
cord-010027-r0tl01kq	1245	23	and	and	CC
cord-010027-r0tl01kq	1245	24	28	28	CD
cord-010027-r0tl01kq	1245	25	%	%	NN
cord-010027-r0tl01kq	1245	26	were	be	VBD
cord-010027-r0tl01kq	1245	27	designated	designate	VBN
cord-010027-r0tl01kq	1245	28	BBC	BBC	NNP
cord-010027-r0tl01kq	1245	29	in	in	IN
cord-010027-r0tl01kq	1245	30	the	the	DT
cord-010027-r0tl01kq	1245	31	report	report	NN
cord-010027-r0tl01kq	1245	32	.	.	.
cord-010027-r0tl01kq	1246	1	16	16	CD
cord-010027-r0tl01kq	1246	2	%	%	NN
cord-010027-r0tl01kq	1246	3	were	be	VBD
cord-010027-r0tl01kq	1246	4	both	both	DT
cord-010027-r0tl01kq	1246	5	TN	TN	NNP
cord-010027-r0tl01kq	1246	6	and	and	CC
cord-010027-r0tl01kq	1246	7	BBC	BBC	NNP
cord-010027-r0tl01kq	1246	8	.	.	.
cord-010027-r0tl01kq	1247	1	Where	where	WRB
cord-010027-r0tl01kq	1247	2	a	a	DT
cord-010027-r0tl01kq	1247	3	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1247	4	of	of	IN
cord-010027-r0tl01kq	1247	5	BBC	BBC	NNP
cord-010027-r0tl01kq	1247	6	was	be	VBD
cord-010027-r0tl01kq	1247	7	made	make	VBN
cord-010027-r0tl01kq	1247	8	,	,	,
cord-010027-r0tl01kq	1247	9	37	37	CD
cord-010027-r0tl01kq	1247	10	%	%	NN
cord-010027-r0tl01kq	1247	11	of	of	IN
cord-010027-r0tl01kq	1247	12	cases	case	NNS
cord-010027-r0tl01kq	1247	13	had	have	VBD
cord-010027-r0tl01kq	1247	14	additional	additional	JJ
cord-010027-r0tl01kq	1247	15	markers	marker	NNS
cord-010027-r0tl01kq	1247	16	requested	request	VBN
cord-010027-r0tl01kq	1247	17	.	.	.
cord-010027-r0tl01kq	1248	1	Preliminary	preliminary	JJ
cord-010027-r0tl01kq	1248	2	results	result	NNS
cord-010027-r0tl01kq	1248	3	showed	show	VBD
cord-010027-r0tl01kq	1248	4	94	94	CD
cord-010027-r0tl01kq	1248	5	%	%	NN
cord-010027-r0tl01kq	1248	6	were	be	VBD
cord-010027-r0tl01kq	1248	7	CK5	ck5	NN
cord-010027-r0tl01kq	1248	8	+	+	CC
cord-010027-r0tl01kq	1248	9	and	and	CC
cord-010027-r0tl01kq	1248	10	CK14	CK14	NNP
cord-010027-r0tl01kq	1248	11	+	+	CC
cord-010027-r0tl01kq	1248	12	.	.	.
cord-010027-r0tl01kq	1249	1	This	this	DT
cord-010027-r0tl01kq	1249	2	is	be	VBZ
cord-010027-r0tl01kq	1249	3	higher	high	JJR
cord-010027-r0tl01kq	1249	4	than	than	IN
cord-010027-r0tl01kq	1249	5	other	other	JJ
cord-010027-r0tl01kq	1249	6	studies	study	NNS
cord-010027-r0tl01kq	1249	7	,	,	,
cord-010027-r0tl01kq	1249	8	implying	imply	VBG
cord-010027-r0tl01kq	1249	9	specificity	specificity	NN
cord-010027-r0tl01kq	1249	10	but	but	CC
cord-010027-r0tl01kq	1249	11	not	not	RB
cord-010027-r0tl01kq	1249	12	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	1249	13	in	in	IN
cord-010027-r0tl01kq	1249	14	suspecting	suspect	VBG
cord-010027-r0tl01kq	1249	15	BBC	BBC	NNP
cord-010027-r0tl01kq	1249	16	amongst	amongst	IN
cord-010027-r0tl01kq	1249	17	reporting	report	VBG
cord-010027-r0tl01kq	1249	18	pathologists	pathologist	NNS
cord-010027-r0tl01kq	1249	19	.	.	.
cord-010027-r0tl01kq	1250	1	Discussion	discussion	NN
cord-010027-r0tl01kq	1250	2	:	:	:
cord-010027-r0tl01kq	1251	1	A	a	DT
cord-010027-r0tl01kq	1251	2	limitation	limitation	NN
cord-010027-r0tl01kq	1251	3	of	of	IN
cord-010027-r0tl01kq	1251	4	this	this	DT
cord-010027-r0tl01kq	1251	5	review	review	NN
cord-010027-r0tl01kq	1251	6	is	be	VBZ
cord-010027-r0tl01kq	1251	7	that	that	IN
cord-010027-r0tl01kq	1251	8	it	-PRON-	PRP
cord-010027-r0tl01kq	1251	9	can	can	MD
cord-010027-r0tl01kq	1251	10	not	not	RB
cord-010027-r0tl01kq	1251	11	identify	identify	VB
cord-010027-r0tl01kq	1251	12	the	the	DT
cord-010027-r0tl01kq	1251	13	rare	rare	JJ
cord-010027-r0tl01kq	1251	14	non	non	NNP
cord-010027-r0tl01kq	1251	15	-	-	NNP
cord-010027-r0tl01kq	1251	16	TN	TN	NNP
cord-010027-r0tl01kq	1251	17	BBC	BBC	NNP
cord-010027-r0tl01kq	1251	18	not	not	RB
cord-010027-r0tl01kq	1251	19	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1251	20	as	as	IN
cord-010027-r0tl01kq	1251	21	such	such	JJ
cord-010027-r0tl01kq	1251	22	.	.	.
cord-010027-r0tl01kq	1252	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1252	2	also	also	RB
cord-010027-r0tl01kq	1252	3	represents	represent	VBZ
cord-010027-r0tl01kq	1252	4	current	current	JJ
cord-010027-r0tl01kq	1252	5	practise	practise	NN
cord-010027-r0tl01kq	1252	6	in	in	IN
cord-010027-r0tl01kq	1252	7	a	a	DT
cord-010027-r0tl01kq	1252	8	single	single	JJ
cord-010027-r0tl01kq	1252	9	institute	institute	NN
cord-010027-r0tl01kq	1252	10	and	and	CC
cord-010027-r0tl01kq	1252	11	may	may	MD
cord-010027-r0tl01kq	1252	12	not	not	RB
cord-010027-r0tl01kq	1252	13	reflect	reflect	VB
cord-010027-r0tl01kq	1252	14	national	national	JJ
cord-010027-r0tl01kq	1252	15	practise	practise	NN
cord-010027-r0tl01kq	1252	16	.	.	.
cord-010027-r0tl01kq	1253	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1253	2	identified	identify	VBD
cord-010027-r0tl01kq	1253	3	patchy	patchy	JJ
cord-010027-r0tl01kq	1253	4	use	use	NN
cord-010027-r0tl01kq	1253	5	of	of	IN
cord-010027-r0tl01kq	1253	6	the	the	DT
cord-010027-r0tl01kq	1253	7	designation	designation	NN
cord-010027-r0tl01kq	1253	8	BBC	BBC	NNP
cord-010027-r0tl01kq	1253	9	,	,	,
cord-010027-r0tl01kq	1253	10	with	with	IN
cord-010027-r0tl01kq	1253	11	overall	overall	JJ
cord-010027-r0tl01kq	1253	12	under	under	IN
cord-010027-r0tl01kq	1253	13	-	-	HYPH
cord-010027-r0tl01kq	1253	14	reporting	reporting	NN
cord-010027-r0tl01kq	1253	15	of	of	IN
cord-010027-r0tl01kq	1253	16	this	this	DT
cord-010027-r0tl01kq	1253	17	subtype	subtype	NN
cord-010027-r0tl01kq	1253	18	.	.	.
cord-010027-r0tl01kq	1254	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1254	2	recommend	recommend	VBP
cord-010027-r0tl01kq	1254	3	that	that	IN
cord-010027-r0tl01kq	1254	4	if	if	IN
cord-010027-r0tl01kq	1254	5	it	-PRON-	PRP
cord-010027-r0tl01kq	1254	6	becomes	become	VBZ
cord-010027-r0tl01kq	1254	7	necessary	necessary	JJ
cord-010027-r0tl01kq	1254	8	to	to	TO
cord-010027-r0tl01kq	1254	9	distinguish	distinguish	VB
cord-010027-r0tl01kq	1254	10	BBC	BBC	NNP
cord-010027-r0tl01kq	1254	11	lesions	lesion	NNS
cord-010027-r0tl01kq	1254	12	,	,	,
cord-010027-r0tl01kq	1254	13	additional	additional	JJ
cord-010027-r0tl01kq	1254	14	markers	marker	NNS
cord-010027-r0tl01kq	1254	15	studies	study	NNS
cord-010027-r0tl01kq	1254	16	,	,	,
cord-010027-r0tl01kq	1254	17	such	such	JJ
cord-010027-r0tl01kq	1254	18	as	as	IN
cord-010027-r0tl01kq	1254	19	CK5	ck5	NN
cord-010027-r0tl01kq	1254	20	and	and	CC
cord-010027-r0tl01kq	1254	21	14	14	CD
cord-010027-r0tl01kq	1254	22	be	be	VB
cord-010027-r0tl01kq	1254	23	consistently	consistently	RB
cord-010027-r0tl01kq	1254	24	performed	perform	VBN
cord-010027-r0tl01kq	1254	25	.	.	.
cord-010027-r0tl01kq	1255	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1255	2	:	:	:
cord-010027-r0tl01kq	1256	1	Neoadjuvant	neoadjuvant	JJ
cord-010027-r0tl01kq	1256	2	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	1256	3	(	(	-LRB-
cord-010027-r0tl01kq	1256	4	NACT	NACT	NNP
cord-010027-r0tl01kq	1256	5	)	)	-RRB-
cord-010027-r0tl01kq	1256	6	is	be	VBZ
cord-010027-r0tl01kq	1256	7	increasingly	increasingly	RB
cord-010027-r0tl01kq	1256	8	used	use	VBN
cord-010027-r0tl01kq	1256	9	for	for	IN
cord-010027-r0tl01kq	1256	10	the	the	DT
cord-010027-r0tl01kq	1256	11	management	management	NN
cord-010027-r0tl01kq	1256	12	of	of	IN
cord-010027-r0tl01kq	1256	13	large	large	JJ
cord-010027-r0tl01kq	1256	14	but	but	CC
cord-010027-r0tl01kq	1256	15	operable	operable	JJ
cord-010027-r0tl01kq	1256	16	,	,	,
cord-010027-r0tl01kq	1256	17	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	1256	18	,	,	,
cord-010027-r0tl01kq	1256	19	and	and	CC
cord-010027-r0tl01kq	1256	20	locally	locally	RB
cord-010027-r0tl01kq	1256	21	advanced	advanced	JJ
cord-010027-r0tl01kq	1256	22	breast	breast	NN
cord-010027-r0tl01kq	1256	23	cancer	cancer	NN
cord-010027-r0tl01kq	1256	24	(	(	-LRB-
cord-010027-r0tl01kq	1256	25	LABC	LABC	NNP
cord-010027-r0tl01kq	1256	26	)	)	-RRB-
cord-010027-r0tl01kq	1256	27	.	.	.
cord-010027-r0tl01kq	1257	1	Little	little	JJ
cord-010027-r0tl01kq	1257	2	is	be	VBZ
cord-010027-r0tl01kq	1257	3	known	know	VBN
cord-010027-r0tl01kq	1257	4	about	about	IN
cord-010027-r0tl01kq	1257	5	predictors	predictor	NNS
cord-010027-r0tl01kq	1257	6	of	of	IN
cord-010027-r0tl01kq	1257	7	response	response	NN
cord-010027-r0tl01kq	1257	8	/	/	SYM
cord-010027-r0tl01kq	1257	9	survival	survival	NN
cord-010027-r0tl01kq	1257	10	following	follow	VBG
cord-010027-r0tl01kq	1257	11	NACT	NACT	NNP
cord-010027-r0tl01kq	1257	12	.	.	.
cord-010027-r0tl01kq	1258	1	The	the	DT
cord-010027-r0tl01kq	1258	2	topoisomerase	topoisomerase	NN
cord-010027-r0tl01kq	1258	3	IIα	iiα	NN
cord-010027-r0tl01kq	1258	4	(	(	-LRB-
cord-010027-r0tl01kq	1258	5	TOP2A	TOP2A	NNP
cord-010027-r0tl01kq	1258	6	)	)	-RRB-
cord-010027-r0tl01kq	1258	7	gene	gene	NN
cord-010027-r0tl01kq	1258	8	,	,	,
cord-010027-r0tl01kq	1258	9	a	a	DT
cord-010027-r0tl01kq	1258	10	key	key	JJ
cord-010027-r0tl01kq	1258	11	regulator	regulator	NN
cord-010027-r0tl01kq	1258	12	of	of	IN
cord-010027-r0tl01kq	1258	13	DNA	dna	NN
cord-010027-r0tl01kq	1258	14	repair	repair	NN
cord-010027-r0tl01kq	1258	15	and	and	CC
cord-010027-r0tl01kq	1258	16	modelling	modelling	NN
cord-010027-r0tl01kq	1258	17	,	,	,
cord-010027-r0tl01kq	1258	18	is	be	VBZ
cord-010027-r0tl01kq	1258	19	thought	think	VBN
cord-010027-r0tl01kq	1258	20	to	to	TO
cord-010027-r0tl01kq	1258	21	be	be	VB
cord-010027-r0tl01kq	1258	22	target	target	NN
cord-010027-r0tl01kq	1258	23	for	for	IN
cord-010027-r0tl01kq	1258	24	anthracyclin	anthracyclin	JJ
cord-010027-r0tl01kq	1258	25	and	and	CC
cord-010027-r0tl01kq	1258	26	other	other	JJ
cord-010027-r0tl01kq	1258	27	chemotherapeutic	chemotherapeutic	JJ
cord-010027-r0tl01kq	1258	28	agents	agent	NNS
cord-010027-r0tl01kq	1258	29	.	.	.
cord-010027-r0tl01kq	1259	1	The	the	DT
cord-010027-r0tl01kq	1259	2	aim	aim	NN
cord-010027-r0tl01kq	1259	3	of	of	IN
cord-010027-r0tl01kq	1259	4	this	this	DT
cord-010027-r0tl01kq	1259	5	study	study	NN
cord-010027-r0tl01kq	1259	6	is	be	VBZ
cord-010027-r0tl01kq	1259	7	to	to	TO
cord-010027-r0tl01kq	1259	8	assess	assess	VB
cord-010027-r0tl01kq	1259	9	the	the	DT
cord-010027-r0tl01kq	1259	10	role	role	NN
cord-010027-r0tl01kq	1259	11	of	of	IN
cord-010027-r0tl01kq	1259	12	TOP2A	top2a	CD
cord-010027-r0tl01kq	1259	13	as	as	IN
cord-010027-r0tl01kq	1259	14	marker	marker	NN
cord-010027-r0tl01kq	1259	15	for	for	IN
cord-010027-r0tl01kq	1259	16	response	response	NN
cord-010027-r0tl01kq	1259	17	/	/	SYM
cord-010027-r0tl01kq	1259	18	resistance	resistance	NN
cord-010027-r0tl01kq	1259	19	to	to	IN
cord-010027-r0tl01kq	1259	20	NACT	NACT	NNP
cord-010027-r0tl01kq	1259	21	and	and	CC
cord-010027-r0tl01kq	1259	22	patient	patient	JJ
cord-010027-r0tl01kq	1259	23	outcome	outcome	NN
cord-010027-r0tl01kq	1259	24	.	.	.
cord-010027-r0tl01kq	1260	1	Methods	method	NNS
cord-010027-r0tl01kq	1260	2	:	:	:
cord-010027-r0tl01kq	1260	3	Patients	patient	NNS
cord-010027-r0tl01kq	1260	4	who	who	WP
cord-010027-r0tl01kq	1260	5	underwent	undergo	VBD
cord-010027-r0tl01kq	1260	6	NACT	NACT	NNP
cord-010027-r0tl01kq	1260	7	,	,	,
cord-010027-r0tl01kq	1260	8	predominantly	predominantly	RB
cord-010027-r0tl01kq	1260	9	anthracyclin	anthracyclin	NNP
cord-010027-r0tl01kq	1260	10	,	,	,
cord-010027-r0tl01kq	1260	11	for	for	IN
cord-010027-r0tl01kq	1260	12	primary	primary	JJ
cord-010027-r0tl01kq	1260	13	and	and	CC
cord-010027-r0tl01kq	1260	14	operable	operable	JJ
cord-010027-r0tl01kq	1260	15	invasive	invasive	JJ
cord-010027-r0tl01kq	1260	16	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1260	17	or	or	CC
cord-010027-r0tl01kq	1260	18	LABC	LABC	NNP
cord-010027-r0tl01kq	1260	19	in	in	IN
cord-010027-r0tl01kq	1260	20	the	the	DT
cord-010027-r0tl01kq	1260	21	period	period	NN
cord-010027-r0tl01kq	1260	22	between	between	IN
cord-010027-r0tl01kq	1260	23	2005	2005	CD
cord-010027-r0tl01kq	1260	24	to	to	IN
cord-010027-r0tl01kq	1260	25	20013	20013	CD
cord-010027-r0tl01kq	1260	26	at	at	IN
cord-010027-r0tl01kq	1260	27	a	a	DT
cord-010027-r0tl01kq	1260	28	single	single	JJ
cord-010027-r0tl01kq	1260	29	large	large	JJ
cord-010027-r0tl01kq	1260	30	tertiary	tertiary	JJ
cord-010027-r0tl01kq	1260	31	referral	referral	JJ
cord-010027-r0tl01kq	1260	32	breast	breast	NN
cord-010027-r0tl01kq	1260	33	unit	unit	NN
cord-010027-r0tl01kq	1260	34	were	be	VBD
cord-010027-r0tl01kq	1260	35	identified	identify	VBN
cord-010027-r0tl01kq	1260	36	.	.	.
cord-010027-r0tl01kq	1261	1	Comprehensive	comprehensive	JJ
cord-010027-r0tl01kq	1261	2	data	datum	NNS
cord-010027-r0tl01kq	1261	3	on	on	IN
cord-010027-r0tl01kq	1261	4	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	1261	5	regimen	regimen	NN
cord-010027-r0tl01kq	1261	6	,	,	,
cord-010027-r0tl01kq	1261	7	surgical	surgical	JJ
cord-010027-r0tl01kq	1261	8	treatment	treatment	NN
cord-010027-r0tl01kq	1261	9	,	,	,
cord-010027-r0tl01kq	1261	10	pathological	pathological	JJ
cord-010027-r0tl01kq	1261	11	response	response	NN
cord-010027-r0tl01kq	1261	12	and	and	CC
cord-010027-r0tl01kq	1261	13	survival	survival	NN
cord-010027-r0tl01kq	1261	14	were	be	VBD
cord-010027-r0tl01kq	1261	15	collected	collect	VBN
cord-010027-r0tl01kq	1261	16	.	.	.
cord-010027-r0tl01kq	1262	1	Pre	pre	JJ
cord-010027-r0tl01kq	1262	2	-	-	JJ
cord-010027-r0tl01kq	1262	3	treatment	treatment	JJ
cord-010027-r0tl01kq	1262	4	tumour	tumour	NN
cord-010027-r0tl01kq	1262	5	samples	sample	NNS
cord-010027-r0tl01kq	1262	6	were	be	VBD
cord-010027-r0tl01kq	1262	7	stained	stain	VBN
cord-010027-r0tl01kq	1262	8	for	for	IN
cord-010027-r0tl01kq	1262	9	standard	standard	JJ
cord-010027-r0tl01kq	1262	10	predictive	predictive	JJ
cord-010027-r0tl01kq	1262	11	and	and	CC
cord-010027-r0tl01kq	1262	12	prognostic	prognostic	JJ
cord-010027-r0tl01kq	1262	13	markers	marker	NNS
cord-010027-r0tl01kq	1262	14	and	and	CC
cord-010027-r0tl01kq	1262	15	TOP2A.	top2a.	NN
cord-010027-r0tl01kq	1262	16	Results	result	NNS
cord-010027-r0tl01kq	1262	17	were	be	VBD
cord-010027-r0tl01kq	1262	18	correlated	correlate	VBN
cord-010027-r0tl01kq	1262	19	with	with	IN
cord-010027-r0tl01kq	1262	20	pathological	pathological	JJ
cord-010027-r0tl01kq	1262	21	response	response	NN
cord-010027-r0tl01kq	1262	22	(	(	-LRB-
cord-010027-r0tl01kq	1262	23	PR	pr	NN
cord-010027-r0tl01kq	1262	24	)	)	-RRB-
cord-010027-r0tl01kq	1262	25	and	and	CC
cord-010027-r0tl01kq	1262	26	patient	patient	JJ
cord-010027-r0tl01kq	1262	27	survival	survival	NN
cord-010027-r0tl01kq	1262	28	.	.	.
cord-010027-r0tl01kq	1263	1	Results	result	NNS
cord-010027-r0tl01kq	1263	2	:	:	:
cord-010027-r0tl01kq	1264	1	252	252	CD
cord-010027-r0tl01kq	1264	2	patients	patient	NNS
cord-010027-r0tl01kq	1264	3	fulfilled	fulfil	VBD
cord-010027-r0tl01kq	1264	4	inclusion	inclusion	NN
cord-010027-r0tl01kq	1264	5	criteria	criterion	NNS
cord-010027-r0tl01kq	1264	6	.	.	.
cord-010027-r0tl01kq	1265	1	Mean	mean	JJ
cord-010027-r0tl01kq	1265	2	age	age	NN
cord-010027-r0tl01kq	1265	3	was	be	VBD
cord-010027-r0tl01kq	1265	4	48.94ys	48.94ys	CD
cord-010027-r0tl01kq	1265	5	.	.	.
cord-010027-r0tl01kq	1266	1	Complete	complete	JJ
cord-010027-r0tl01kq	1266	2	PR	PR	NNP
cord-010027-r0tl01kq	1266	3	was	be	VBD
cord-010027-r0tl01kq	1266	4	achieved	achieve	VBN
cord-010027-r0tl01kq	1266	5	in	in	IN
cord-010027-r0tl01kq	1266	6	15.4	15.4	CD
cord-010027-r0tl01kq	1266	7	%	%	NN
cord-010027-r0tl01kq	1266	8	.	.	.
cord-010027-r0tl01kq	1267	1	The	the	DT
cord-010027-r0tl01kq	1267	2	mean	mean	JJ
cord-010027-r0tl01kq	1267	3	expression	expression	NN
cord-010027-r0tl01kq	1267	4	level	level	NN
cord-010027-r0tl01kq	1267	5	of	of	IN
cord-010027-r0tl01kq	1267	6	TOP2A	top2a	CD
cord-010027-r0tl01kq	1267	7	in	in	IN
cord-010027-r0tl01kq	1267	8	pre	pre	JJ
cord-010027-r0tl01kq	1267	9	-	-	JJ
cord-010027-r0tl01kq	1267	10	treatment	treatment	JJ
cord-010027-r0tl01kq	1267	11	core	core	NN
cord-010027-r0tl01kq	1267	12	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1267	13	was	be	VBD
cord-010027-r0tl01kq	1267	14	75.4	75.4	CD
cord-010027-r0tl01kq	1267	15	%	%	NN
cord-010027-r0tl01kq	1267	16	,	,	,
cord-010027-r0tl01kq	1267	17	range	range	VBP
cord-010027-r0tl01kq	1267	18	0	0	CD
cord-010027-r0tl01kq	1267	19	-	-	SYM
cord-010027-r0tl01kq	1267	20	95	95	CD
cord-010027-r0tl01kq	1267	21	%	%	NN
cord-010027-r0tl01kq	1267	22	.	.	.
cord-010027-r0tl01kq	1268	1	There	there	EX
cord-010027-r0tl01kq	1268	2	was	be	VBD
cord-010027-r0tl01kq	1268	3	significantly	significantly	RB
cord-010027-r0tl01kq	1268	4	higher	high	JJR
cord-010027-r0tl01kq	1268	5	expression	expression	NN
cord-010027-r0tl01kq	1268	6	in	in	IN
cord-010027-r0tl01kq	1268	7	high	high	JJ
cord-010027-r0tl01kq	1268	8	grade	grade	NN
cord-010027-r0tl01kq	1268	9	tumours	tumour	NNS
cord-010027-r0tl01kq	1268	10	(	(	-LRB-
cord-010027-r0tl01kq	1268	11	p=0.04	p=0.04	NN
cord-010027-r0tl01kq	1268	12	)	)	-RRB-
cord-010027-r0tl01kq	1268	13	and	and	CC
cord-010027-r0tl01kq	1268	14	positive	positive	JJ
cord-010027-r0tl01kq	1268	15	correlation	correlation	NN
cord-010027-r0tl01kq	1268	16	with	with	IN
cord-010027-r0tl01kq	1268	17	ki67	ki67	NNP
cord-010027-r0tl01kq	1268	18	expression	expression	NN
cord-010027-r0tl01kq	1268	19	(	(	-LRB-
cord-010027-r0tl01kq	1268	20	r=0.405	r=0.405	ADD
cord-010027-r0tl01kq	1268	21	,	,	,
cord-010027-r0tl01kq	1268	22	p<0.001	p<0.001	CD
cord-010027-r0tl01kq	1268	23	)	)	-RRB-
cord-010027-r0tl01kq	1268	24	.	.	.
cord-010027-r0tl01kq	1269	1	There	there	EX
cord-010027-r0tl01kq	1269	2	was	be	VBD
cord-010027-r0tl01kq	1269	3	no	no	DT
cord-010027-r0tl01kq	1269	4	correlation	correlation	NN
cord-010027-r0tl01kq	1269	5	with	with	IN
cord-010027-r0tl01kq	1269	6	nodal	nodal	JJ
cord-010027-r0tl01kq	1269	7	status	status	NN
cord-010027-r0tl01kq	1269	8	,	,	,
cord-010027-r0tl01kq	1269	9	PR	PR	NNP
cord-010027-r0tl01kq	1269	10	or	or	CC
cord-010027-r0tl01kq	1269	11	HER2	her2	JJ
cord-010027-r0tl01kq	1269	12	expression	expression	NN
cord-010027-r0tl01kq	1269	13	.	.	.
cord-010027-r0tl01kq	1270	1	Cases	case	NNS
cord-010027-r0tl01kq	1270	2	with	with	IN
cord-010027-r0tl01kq	1270	3	high	high	JJ
cord-010027-r0tl01kq	1270	4	expression	expression	NN
cord-010027-r0tl01kq	1270	5	(	(	-LRB-
cord-010027-r0tl01kq	1270	6	>	>	NFP
cord-010027-r0tl01kq	1270	7	50	50	CD
cord-010027-r0tl01kq	1270	8	%	%	NN
cord-010027-r0tl01kq	1270	9	)	)	-RRB-
cord-010027-r0tl01kq	1270	10	,	,	,
cord-010027-r0tl01kq	1270	11	had	have	VBD
cord-010027-r0tl01kq	1270	12	significantly	significantly	RB
cord-010027-r0tl01kq	1270	13	worse	bad	JJR
cord-010027-r0tl01kq	1270	14	overall	overall	JJ
cord-010027-r0tl01kq	1270	15	survival	survival	NN
cord-010027-r0tl01kq	1270	16	(	(	-LRB-
cord-010027-r0tl01kq	1270	17	mean	mean	VB
cord-010027-r0tl01kq	1270	18	38	38	CD
cord-010027-r0tl01kq	1270	19	vs	vs	IN
cord-010027-r0tl01kq	1270	20	52	52	CD
cord-010027-r0tl01kq	1270	21	months	month	NNS
cord-010027-r0tl01kq	1270	22	,	,	,
cord-010027-r0tl01kq	1270	23	p=0.01	p=0.01	NNP
cord-010027-r0tl01kq	1270	24	)	)	-RRB-
cord-010027-r0tl01kq	1270	25	.	.	.
cord-010027-r0tl01kq	1271	1	This	this	DT
cord-010027-r0tl01kq	1271	2	was	be	VBD
cord-010027-r0tl01kq	1271	3	also	also	RB
cord-010027-r0tl01kq	1271	4	identified	identify	VBN
cord-010027-r0tl01kq	1271	5	in	in	IN
cord-010027-r0tl01kq	1271	6	the	the	DT
cord-010027-r0tl01kq	1271	7	endocrine	endocrine	JJ
cord-010027-r0tl01kq	1271	8	non	non	AFX
cord-010027-r0tl01kq	1271	9	responsive	responsive	JJ
cord-010027-r0tl01kq	1271	10	group	group	NN
cord-010027-r0tl01kq	1271	11	(	(	-LRB-
cord-010027-r0tl01kq	1271	12	ER	ER	NNP
cord-010027-r0tl01kq	1271	13	Allred	Allred	NNP
cord-010027-r0tl01kq	1271	14	score≤4	score≤4	NNP
cord-010027-r0tl01kq	1271	15	)	)	-RRB-
cord-010027-r0tl01kq	1271	16	,	,	,
cord-010027-r0tl01kq	1271	17	mean	mean	VBP
cord-010027-r0tl01kq	1271	18	74	74	CD
cord-010027-r0tl01kq	1271	19	vs	vs	IN
cord-010027-r0tl01kq	1271	20	33	33	CD
cord-010027-r0tl01kq	1271	21	months	month	NNS
cord-010027-r0tl01kq	1271	22	,	,	,
cord-010027-r0tl01kq	1271	23	p=0.04	p=0.04	NNP
cord-010027-r0tl01kq	1271	24	.	.	.
cord-010027-r0tl01kq	1272	1	On	on	IN
cord-010027-r0tl01kq	1272	2	multivariate	multivariate	JJ
cord-010027-r0tl01kq	1272	3	analysis	analysis	NN
cord-010027-r0tl01kq	1272	4	,	,	,
cord-010027-r0tl01kq	1272	5	TOP2A	TOP2A	NNP
cord-010027-r0tl01kq	1272	6	was	be	VBD
cord-010027-r0tl01kq	1272	7	not	not	RB
cord-010027-r0tl01kq	1272	8	an	an	DT
cord-010027-r0tl01kq	1272	9	independent	independent	JJ
cord-010027-r0tl01kq	1272	10	factor	factor	NN
cord-010027-r0tl01kq	1272	11	for	for	IN
cord-010027-r0tl01kq	1272	12	overall	overall	JJ
cord-010027-r0tl01kq	1272	13	survival	survival	NN
cord-010027-r0tl01kq	1272	14	.	.	.
cord-010027-r0tl01kq	1273	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1273	2	:	:	:
cord-010027-r0tl01kq	1274	1	TOP2A	top2a	CD
cord-010027-r0tl01kq	1275	1	protein	protein	NN
cord-010027-r0tl01kq	1275	2	is	be	VBZ
cord-010027-r0tl01kq	1275	3	expressed	express	VBN
cord-010027-r0tl01kq	1275	4	in	in	IN
cord-010027-r0tl01kq	1275	5	high	high	JJ
cord-010027-r0tl01kq	1275	6	grade	grade	NN
cord-010027-r0tl01kq	1275	7	breast	breast	NN
cord-010027-r0tl01kq	1275	8	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1275	9	with	with	IN
cord-010027-r0tl01kq	1275	10	high	high	JJ
cord-010027-r0tl01kq	1275	11	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1275	12	proliferation	proliferation	NN
cord-010027-r0tl01kq	1275	13	index	index	NN
cord-010027-r0tl01kq	1275	14	.	.	.
cord-010027-r0tl01kq	1276	1	Its	-PRON-	PRP$
cord-010027-r0tl01kq	1276	2	expression	expression	NN
cord-010027-r0tl01kq	1276	3	in	in	IN
cord-010027-r0tl01kq	1276	4	pre	pre	JJ
cord-010027-r0tl01kq	1276	5	-	-	JJ
cord-010027-r0tl01kq	1276	6	treatment	treatment	JJ
cord-010027-r0tl01kq	1276	7	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1276	8	predicted	predict	VBD
cord-010027-r0tl01kq	1276	9	patient	patient	JJ
cord-010027-r0tl01kq	1276	10	outcome	outcome	NN
cord-010027-r0tl01kq	1276	11	in	in	IN
cord-010027-r0tl01kq	1276	12	the	the	DT
cord-010027-r0tl01kq	1276	13	neoadjuvant	neoadjuvant	JJ
cord-010027-r0tl01kq	1276	14	setting	setting	NN
cord-010027-r0tl01kq	1276	15	.	.	.
cord-010027-r0tl01kq	1277	1	This	this	DT
cord-010027-r0tl01kq	1277	2	strong	strong	JJ
cord-010027-r0tl01kq	1277	3	adverse	adverse	JJ
cord-010027-r0tl01kq	1277	4	effect	effect	NN
cord-010027-r0tl01kq	1277	5	on	on	IN
cord-010027-r0tl01kq	1277	6	survival	survival	NN
cord-010027-r0tl01kq	1277	7	warrents	warrent	NNS
cord-010027-r0tl01kq	1277	8	further	further	JJ
cord-010027-r0tl01kq	1277	9	prospective	prospective	JJ
cord-010027-r0tl01kq	1277	10	investigation	investigation	NN
cord-010027-r0tl01kq	1277	11	as	as	IN
cord-010027-r0tl01kq	1277	12	a	a	DT
cord-010027-r0tl01kq	1277	13	marker	marker	NN
cord-010027-r0tl01kq	1277	14	of	of	IN
cord-010027-r0tl01kq	1277	15	outcome	outcome	NN
cord-010027-r0tl01kq	1277	16	in	in	IN
cord-010027-r0tl01kq	1277	17	NACT	NACT	NNP
cord-010027-r0tl01kq	1277	18	patients	patient	NNS
cord-010027-r0tl01kq	1277	19	.	.	.
cord-010027-r0tl01kq	1278	1	The	the	DT
cord-010027-r0tl01kq	1278	2	risk	risk	NN
cord-010027-r0tl01kq	1278	3	of	of	IN
cord-010027-r0tl01kq	1278	4	circumferential	circumferential	JJ
cord-010027-r0tl01kq	1278	5	resection	resection	NN
cord-010027-r0tl01kq	1278	6	margin	margin	NN
cord-010027-r0tl01kq	1278	7	(	(	-LRB-
cord-010027-r0tl01kq	1278	8	CRM	CRM	NNP
cord-010027-r0tl01kq	1278	9	)	)	-RRB-
cord-010027-r0tl01kq	1278	10	involvement	involvement	NN
cord-010027-r0tl01kq	1278	11	is	be	VBZ
cord-010027-r0tl01kq	1278	12	confined	confine	VBN
cord-010027-r0tl01kq	1278	13	to	to	IN
cord-010027-r0tl01kq	1278	14	tumours	tumour	NNS
cord-010027-r0tl01kq	1278	15	of	of	IN
cord-010027-r0tl01kq	1278	16	the	the	DT
cord-010027-r0tl01kq	1278	17	rectum	rectum	NN
cord-010027-r0tl01kq	1278	18	with	with	IN
cord-010027-r0tl01kq	1278	19	the	the	DT
cord-010027-r0tl01kq	1278	20	risk	risk	NN
cord-010027-r0tl01kq	1278	21	of	of	IN
cord-010027-r0tl01kq	1278	22	peritoneal	peritoneal	JJ
cord-010027-r0tl01kq	1278	23	involvement	involvement	NN
cord-010027-r0tl01kq	1278	24	increasing	increase	VBG
cord-010027-r0tl01kq	1278	25	the	the	DT
cord-010027-r0tl01kq	1278	26	further	further	JJ
cord-010027-r0tl01kq	1278	27	a	a	DT
cord-010027-r0tl01kq	1278	28	tumour	tumour	NN
cord-010027-r0tl01kq	1278	29	is	be	VBZ
cord-010027-r0tl01kq	1278	30	located	locate	VBN
cord-010027-r0tl01kq	1278	31	above	above	IN
cord-010027-r0tl01kq	1278	32	the	the	DT
cord-010027-r0tl01kq	1278	33	peritoneal	peritoneal	JJ
cord-010027-r0tl01kq	1278	34	reflection	reflection	NN
cord-010027-r0tl01kq	1278	35	.	.	.
cord-010027-r0tl01kq	1279	1	There	there	EX
cord-010027-r0tl01kq	1279	2	is	be	VBZ
cord-010027-r0tl01kq	1279	3	no	no	DT
cord-010027-r0tl01kq	1279	4	internationally	internationally	RB
cord-010027-r0tl01kq	1279	5	accepted	accept	VBN
cord-010027-r0tl01kq	1279	6	definition	definition	NN
cord-010027-r0tl01kq	1279	7	of	of	IN
cord-010027-r0tl01kq	1279	8	the	the	DT
cord-010027-r0tl01kq	1279	9	upper	upper	JJ
cord-010027-r0tl01kq	1279	10	limit	limit	NN
cord-010027-r0tl01kq	1279	11	of	of	IN
cord-010027-r0tl01kq	1279	12	the	the	DT
cord-010027-r0tl01kq	1279	13	rectum	rectum	NN
cord-010027-r0tl01kq	1279	14	,	,	,
cord-010027-r0tl01kq	1279	15	and	and	CC
cord-010027-r0tl01kq	1279	16	the	the	DT
cord-010027-r0tl01kq	1279	17	term	term	NN
cord-010027-r0tl01kq	1279	18	'	'	``
cord-010027-r0tl01kq	1279	19	rectosigmoid	rectosigmoid	JJ
cord-010027-r0tl01kq	1279	20	'	'	''
cord-010027-r0tl01kq	1279	21	is	be	VBZ
cord-010027-r0tl01kq	1279	22	frequently	frequently	RB
cord-010027-r0tl01kq	1279	23	applied	apply	VBN
cord-010027-r0tl01kq	1279	24	to	to	IN
cord-010027-r0tl01kq	1279	25	tumours	tumour	NNS
cord-010027-r0tl01kq	1279	26	in	in	IN
cord-010027-r0tl01kq	1279	27	this	this	DT
cord-010027-r0tl01kq	1279	28	area	area	NN
cord-010027-r0tl01kq	1279	29	leading	lead	VBG
cord-010027-r0tl01kq	1279	30	to	to	IN
cord-010027-r0tl01kq	1279	31	confusion	confusion	NN
cord-010027-r0tl01kq	1279	32	around	around	IN
cord-010027-r0tl01kq	1279	33	the	the	DT
cord-010027-r0tl01kq	1279	34	risks	risk	NNS
cord-010027-r0tl01kq	1279	35	and	and	CC
cord-010027-r0tl01kq	1279	36	whether	whether	IN
cord-010027-r0tl01kq	1279	37	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1279	38	can	can	MD
cord-010027-r0tl01kq	1279	39	be	be	VB
cord-010027-r0tl01kq	1279	40	given	give	VBN
cord-010027-r0tl01kq	1279	41	.	.	.
cord-010027-r0tl01kq	1280	1	The	the	DT
cord-010027-r0tl01kq	1280	2	photographs	photograph	NNS
cord-010027-r0tl01kq	1280	3	from	from	IN
cord-010027-r0tl01kq	1280	4	331	331	CD
cord-010027-r0tl01kq	1280	5	abdominoperineal	abdominoperineal	NN
cord-010027-r0tl01kq	1280	6	excision	excision	NN
cord-010027-r0tl01kq	1280	7	specimens	specimen	NNS
cord-010027-r0tl01kq	1280	8	were	be	VBD
cord-010027-r0tl01kq	1280	9	available	available	JJ
cord-010027-r0tl01kq	1280	10	for	for	IN
cord-010027-r0tl01kq	1280	11	quantitation	quantitation	NN
cord-010027-r0tl01kq	1280	12	using	use	VBG
cord-010027-r0tl01kq	1280	13	Aperio	Aperio	NNP
cord-010027-r0tl01kq	1280	14	ImageScope	ImageScope	NNP
cord-010027-r0tl01kq	1280	15	.	.	.
cord-010027-r0tl01kq	1281	1	Both	both	CC
cord-010027-r0tl01kq	1281	2	fresh	fresh	JJ
cord-010027-r0tl01kq	1281	3	and	and	CC
cord-010027-r0tl01kq	1281	4	fixed	fixed	JJ
cord-010027-r0tl01kq	1281	5	specimen	specimen	JJ
cord-010027-r0tl01kq	1281	6	images	image	NNS
cord-010027-r0tl01kq	1281	7	were	be	VBD
cord-010027-r0tl01kq	1281	8	included	include	VBN
cord-010027-r0tl01kq	1281	9	where	where	WRB
cord-010027-r0tl01kq	1281	10	available	available	JJ
cord-010027-r0tl01kq	1281	11	.	.	.
cord-010027-r0tl01kq	1282	1	The	the	DT
cord-010027-r0tl01kq	1282	2	position	position	NN
cord-010027-r0tl01kq	1282	3	of	of	IN
cord-010027-r0tl01kq	1282	4	the	the	DT
cord-010027-r0tl01kq	1282	5	anal	anal	JJ
cord-010027-r0tl01kq	1282	6	verge	verge	NN
cord-010027-r0tl01kq	1282	7	,	,	,
cord-010027-r0tl01kq	1282	8	top	top	NN
cord-010027-r0tl01kq	1282	9	of	of	IN
cord-010027-r0tl01kq	1282	10	the	the	DT
cord-010027-r0tl01kq	1282	11	sphincters	sphincter	NNS
cord-010027-r0tl01kq	1282	12	,	,	,
cord-010027-r0tl01kq	1282	13	anterior	anterior	JJ
cord-010027-r0tl01kq	1282	14	peritoneal	peritoneal	JJ
cord-010027-r0tl01kq	1282	15	reflection	reflection	NN
cord-010027-r0tl01kq	1282	16	,	,	,
cord-010027-r0tl01kq	1282	17	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1282	18	apex	apex	NNP
cord-010027-r0tl01kq	1282	19	(	(	-LRB-
cord-010027-r0tl01kq	1282	20	defining	define	VBG
cord-010027-r0tl01kq	1282	21	the	the	DT
cord-010027-r0tl01kq	1282	22	limit	limit	NN
cord-010027-r0tl01kq	1282	23	of	of	IN
cord-010027-r0tl01kq	1282	24	the	the	DT
cord-010027-r0tl01kq	1282	25	mesorectum	mesorectum	NN
cord-010027-r0tl01kq	1282	26	)	)	-RRB-
cord-010027-r0tl01kq	1282	27	and	and	CC
cord-010027-r0tl01kq	1282	28	high	high	JJ
cord-010027-r0tl01kq	1282	29	vascular	vascular	JJ
cord-010027-r0tl01kq	1282	30	tie	tie	NN
cord-010027-r0tl01kq	1282	31	were	be	VBD
cord-010027-r0tl01kq	1282	32	identified	identify	VBN
cord-010027-r0tl01kq	1282	33	and	and	CC
cord-010027-r0tl01kq	1282	34	the	the	DT
cord-010027-r0tl01kq	1282	35	distances	distance	NNS
cord-010027-r0tl01kq	1282	36	between	between	IN
cord-010027-r0tl01kq	1282	37	each	each	DT
cord-010027-r0tl01kq	1282	38	point	point	NN
cord-010027-r0tl01kq	1282	39	measured	measure	VBN
cord-010027-r0tl01kq	1282	40	.	.	.
cord-010027-r0tl01kq	1283	1	The	the	DT
cord-010027-r0tl01kq	1283	2	work	work	NN
cord-010027-r0tl01kq	1283	3	was	be	VBD
cord-010027-r0tl01kq	1283	4	supported	support	VBN
cord-010027-r0tl01kq	1283	5	by	by	IN
cord-010027-r0tl01kq	1283	6	a	a	DT
cord-010027-r0tl01kq	1283	7	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	1283	8	bursary	bursary	NN
cord-010027-r0tl01kq	1283	9	.	.	.
cord-010027-r0tl01kq	1284	1	There	there	EX
cord-010027-r0tl01kq	1284	2	was	be	VBD
cord-010027-r0tl01kq	1284	3	wide	wide	JJ
cord-010027-r0tl01kq	1284	4	variation	variation	NN
cord-010027-r0tl01kq	1284	5	in	in	IN
cord-010027-r0tl01kq	1284	6	the	the	DT
cord-010027-r0tl01kq	1284	7	length	length	NN
cord-010027-r0tl01kq	1284	8	of	of	IN
cord-010027-r0tl01kq	1284	9	the	the	DT
cord-010027-r0tl01kq	1284	10	mesorectum	mesorectum	NN
cord-010027-r0tl01kq	1284	11	in	in	IN
cord-010027-r0tl01kq	1284	12	both	both	CC
cord-010027-r0tl01kq	1284	13	fresh	fresh	JJ
cord-010027-r0tl01kq	1284	14	(	(	-LRB-
cord-010027-r0tl01kq	1284	15	median	median	NN
cord-010027-r0tl01kq	1284	16	172	172	CD
cord-010027-r0tl01kq	1284	17	mm	mm	NN
cord-010027-r0tl01kq	1284	18	,	,	,
cord-010027-r0tl01kq	1284	19	IQR	IQR	NNP
cord-010027-r0tl01kq	1284	20	146	146	CD
cord-010027-r0tl01kq	1284	21	to	to	IN
cord-010027-r0tl01kq	1284	22	199	199	CD
cord-010027-r0tl01kq	1284	23	mm	mm	NNS
cord-010027-r0tl01kq	1284	24	)	)	-RRB-
cord-010027-r0tl01kq	1284	25	and	and	CC
cord-010027-r0tl01kq	1284	26	fixed	fix	VBN
cord-010027-r0tl01kq	1284	27	(	(	-LRB-
cord-010027-r0tl01kq	1284	28	166	166	CD
cord-010027-r0tl01kq	1284	29	mm	mm	NNS
cord-010027-r0tl01kq	1284	30	,	,	,
cord-010027-r0tl01kq	1284	31	140	140	CD
cord-010027-r0tl01kq	1284	32	to	to	TO
cord-010027-r0tl01kq	1284	33	196	196	CD
cord-010027-r0tl01kq	1284	34	mm	mm	NNS
cord-010027-r0tl01kq	1284	35	)	)	-RRB-
cord-010027-r0tl01kq	1284	36	specimens	specimen	NNS
cord-010027-r0tl01kq	1284	37	.	.	.
cord-010027-r0tl01kq	1285	1	The	the	DT
cord-010027-r0tl01kq	1285	2	length	length	NN
cord-010027-r0tl01kq	1285	3	of	of	IN
cord-010027-r0tl01kq	1285	4	the	the	DT
cord-010027-r0tl01kq	1285	5	anal	anal	JJ
cord-010027-r0tl01kq	1285	6	canal	canal	NNP
cord-010027-r0tl01kq	1285	7	also	also	RB
cord-010027-r0tl01kq	1285	8	showed	show	VBD
cord-010027-r0tl01kq	1285	9	variation	variation	NN
cord-010027-r0tl01kq	1285	10	(	(	-LRB-
cord-010027-r0tl01kq	1285	11	fresh	fresh	JJ
cord-010027-r0tl01kq	1285	12	66	66	CD
cord-010027-r0tl01kq	1285	13	mm	mm	NN
cord-010027-r0tl01kq	1285	14	,	,	,
cord-010027-r0tl01kq	1285	15	49	49	CD
cord-010027-r0tl01kq	1285	16	to	to	TO
cord-010027-r0tl01kq	1285	17	78	78	CD
cord-010027-r0tl01kq	1285	18	mm	mm	NNS
cord-010027-r0tl01kq	1285	19	;	;	,
cord-010027-r0tl01kq	1285	20	fixed	fix	VBN
cord-010027-r0tl01kq	1285	21	66	66	CD
cord-010027-r0tl01kq	1285	22	mm	mm	NNS
cord-010027-r0tl01kq	1285	23	,	,	,
cord-010027-r0tl01kq	1285	24	53	53	CD
cord-010027-r0tl01kq	1285	25	to	to	TO
cord-010027-r0tl01kq	1285	26	75	75	CD
cord-010027-r0tl01kq	1285	27	mm	mm	NNS
cord-010027-r0tl01kq	1285	28	)	)	-RRB-
cord-010027-r0tl01kq	1285	29	.	.	.
cord-010027-r0tl01kq	1286	1	The	the	DT
cord-010027-r0tl01kq	1286	2	height	height	NN
cord-010027-r0tl01kq	1286	3	of	of	IN
cord-010027-r0tl01kq	1286	4	the	the	DT
cord-010027-r0tl01kq	1286	5	anterior	anterior	NNP
cord-010027-r0tl01kq	1286	6	peritoneal	peritoneal	JJ
cord-010027-r0tl01kq	1286	7	reflection	reflection	NN
cord-010027-r0tl01kq	1286	8	was	be	VBD
cord-010027-r0tl01kq	1286	9	lower	low	JJR
cord-010027-r0tl01kq	1286	10	in	in	IN
cord-010027-r0tl01kq	1286	11	females	female	NNS
cord-010027-r0tl01kq	1286	12	compared	compare	VBN
cord-010027-r0tl01kq	1286	13	to	to	IN
cord-010027-r0tl01kq	1286	14	males	male	NNS
cord-010027-r0tl01kq	1286	15	(	(	-LRB-
cord-010027-r0tl01kq	1286	16	fresh	fresh	JJ
cord-010027-r0tl01kq	1286	17	125	125	CD
cord-010027-r0tl01kq	1286	18	vs.	vs.	NN
cord-010027-r0tl01kq	1286	19	132	132	CD
cord-010027-r0tl01kq	1286	20	mm	mm	NNS
cord-010027-r0tl01kq	1286	21	,	,	,
cord-010027-r0tl01kq	1286	22	p=0.288	p=0.288	NNP
cord-010027-r0tl01kq	1287	1	;	;	:
cord-010027-r0tl01kq	1287	2	fixed	fix	VBN
cord-010027-r0tl01kq	1287	3	111	111	CD
cord-010027-r0tl01kq	1287	4	vs.	vs.	NN
cord-010027-r0tl01kq	1287	5	126	126	CD
cord-010027-r0tl01kq	1287	6	mm	mm	NNS
cord-010027-r0tl01kq	1287	7	,	,	,
cord-010027-r0tl01kq	1287	8	p=0.034	p=0.034	NNP
cord-010027-r0tl01kq	1287	9	)	)	-RRB-
cord-010027-r0tl01kq	1287	10	.	.	.
cord-010027-r0tl01kq	1288	1	There	there	EX
cord-010027-r0tl01kq	1288	2	is	be	VBZ
cord-010027-r0tl01kq	1288	3	marked	mark	VBN
cord-010027-r0tl01kq	1288	4	variability	variability	NN
cord-010027-r0tl01kq	1288	5	in	in	IN
cord-010027-r0tl01kq	1288	6	the	the	DT
cord-010027-r0tl01kq	1288	7	anatomy	anatomy	NN
cord-010027-r0tl01kq	1288	8	of	of	IN
cord-010027-r0tl01kq	1288	9	the	the	DT
cord-010027-r0tl01kq	1288	10	rectum	rectum	NN
cord-010027-r0tl01kq	1288	11	between	between	IN
cord-010027-r0tl01kq	1288	12	individuals	individual	NNS
cord-010027-r0tl01kq	1288	13	and	and	CC
cord-010027-r0tl01kq	1288	14	genders	gender	NNS
cord-010027-r0tl01kq	1288	15	.	.	.
cord-010027-r0tl01kq	1289	1	This	this	DT
cord-010027-r0tl01kq	1289	2	potentially	potentially	RB
cord-010027-r0tl01kq	1289	3	affects	affect	VBZ
cord-010027-r0tl01kq	1289	4	the	the	DT
cord-010027-r0tl01kq	1289	5	risk	risk	NN
cord-010027-r0tl01kq	1289	6	of	of	IN
cord-010027-r0tl01kq	1289	7	either	either	DT
cord-010027-r0tl01kq	1289	8	CRM	CRM	NNP
cord-010027-r0tl01kq	1289	9	or	or	CC
cord-010027-r0tl01kq	1289	10	peritoneal	peritoneal	JJ
cord-010027-r0tl01kq	1289	11	involvement	involvement	NN
cord-010027-r0tl01kq	1289	12	and	and	CC
cord-010027-r0tl01kq	1289	13	whether	whether	IN
cord-010027-r0tl01kq	1289	14	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1289	15	could	could	MD
cord-010027-r0tl01kq	1289	16	be	be	VB
cord-010027-r0tl01kq	1289	17	offered	offer	VBN
cord-010027-r0tl01kq	1289	18	.	.	.
cord-010027-r0tl01kq	1290	1	A	a	DT
cord-010027-r0tl01kq	1290	2	fixed	fix	VBN
cord-010027-r0tl01kq	1290	3	definition	definition	NN
cord-010027-r0tl01kq	1290	4	of	of	IN
cord-010027-r0tl01kq	1290	5	the	the	DT
cord-010027-r0tl01kq	1290	6	upper	upper	JJ
cord-010027-r0tl01kq	1290	7	limit	limit	NN
cord-010027-r0tl01kq	1290	8	of	of	IN
cord-010027-r0tl01kq	1290	9	the	the	DT
cord-010027-r0tl01kq	1290	10	rectum	rectum	NN
cord-010027-r0tl01kq	1290	11	for	for	IN
cord-010027-r0tl01kq	1290	12	all	all	DT
cord-010027-r0tl01kq	1290	13	patients	patient	NNS
cord-010027-r0tl01kq	1290	14	is	be	VBZ
cord-010027-r0tl01kq	1290	15	not	not	RB
cord-010027-r0tl01kq	1290	16	helpful	helpful	JJ
cord-010027-r0tl01kq	1290	17	.	.	.
cord-010027-r0tl01kq	1291	1	This	this	DT
cord-010027-r0tl01kq	1291	2	should	should	MD
cord-010027-r0tl01kq	1291	3	be	be	VB
cord-010027-r0tl01kq	1291	4	determined	determine	VBN
cord-010027-r0tl01kq	1291	5	for	for	IN
cord-010027-r0tl01kq	1291	6	individual	individual	JJ
cord-010027-r0tl01kq	1291	7	patients	patient	NNS
cord-010027-r0tl01kq	1291	8	on	on	IN
cord-010027-r0tl01kq	1291	9	the	the	DT
cord-010027-r0tl01kq	1291	10	basis	basis	NN
cord-010027-r0tl01kq	1291	11	of	of	IN
cord-010027-r0tl01kq	1291	12	the	the	DT
cord-010027-r0tl01kq	1291	13	MRI	MRI	NNP
cord-010027-r0tl01kq	1291	14	findings	finding	NNS
cord-010027-r0tl01kq	1291	15	.	.	.
cord-010027-r0tl01kq	1292	1	The	the	DT
cord-010027-r0tl01kq	1292	2	term	term	NN
cord-010027-r0tl01kq	1292	3	'	'	``
cord-010027-r0tl01kq	1292	4	rectosigmoid	rectosigmoid	JJ
cord-010027-r0tl01kq	1292	5	'	'	''
cord-010027-r0tl01kq	1292	6	should	should	MD
cord-010027-r0tl01kq	1292	7	be	be	VB
cord-010027-r0tl01kq	1292	8	abolished	abolish	VBN
cord-010027-r0tl01kq	1292	9	and	and	CC
cord-010027-r0tl01kq	1292	10	more	more	RBR
cord-010027-r0tl01kq	1292	11	accurate	accurate	JJ
cord-010027-r0tl01kq	1292	12	definitions	definition	NNS
cord-010027-r0tl01kq	1292	13	based	base	VBN
cord-010027-r0tl01kq	1292	14	on	on	IN
cord-010027-r0tl01kq	1292	15	the	the	DT
cord-010027-r0tl01kq	1292	16	position	position	NN
cord-010027-r0tl01kq	1292	17	of	of	IN
cord-010027-r0tl01kq	1292	18	the	the	DT
cord-010027-r0tl01kq	1292	19	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1292	20	apex	apex	NN
cord-010027-r0tl01kq	1292	21	and	and	CC
cord-010027-r0tl01kq	1292	22	commencement	commencement	NN
cord-010027-r0tl01kq	1292	23	of	of	IN
cord-010027-r0tl01kq	1292	24	the	the	DT
cord-010027-r0tl01kq	1292	25	sigmoid	sigmoid	JJ
cord-010027-r0tl01kq	1292	26	mesentery	mesentery	NN
cord-010027-r0tl01kq	1292	27	should	should	MD
cord-010027-r0tl01kq	1292	28	be	be	VB
cord-010027-r0tl01kq	1292	29	used	use	VBN
cord-010027-r0tl01kq	1292	30	to	to	TO
cord-010027-r0tl01kq	1292	31	define	define	VB
cord-010027-r0tl01kq	1292	32	the	the	DT
cord-010027-r0tl01kq	1292	33	boundaries	boundary	NNS
cord-010027-r0tl01kq	1292	34	of	of	IN
cord-010027-r0tl01kq	1292	35	the	the	DT
cord-010027-r0tl01kq	1292	36	rectum	rectum	NN
cord-010027-r0tl01kq	1292	37	and	and	CC
cord-010027-r0tl01kq	1292	38	sigmoid	sigmoid	JJ
cord-010027-r0tl01kq	1292	39	colon	colon	NN
cord-010027-r0tl01kq	1292	40	and	and	CC
cord-010027-r0tl01kq	1292	41	determine	determine	VB
cord-010027-r0tl01kq	1292	42	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1292	43	risks	risk	NNS
cord-010027-r0tl01kq	1292	44	to	to	IN
cord-010027-r0tl01kq	1292	45	the	the	DT
cord-010027-r0tl01kq	1292	46	patient	patient	NN
cord-010027-r0tl01kq	1292	47	.	.	.
cord-010027-r0tl01kq	1293	1	Pre	pre	JJ
cord-010027-r0tl01kq	1293	2	-	-	JJ
cord-010027-r0tl01kq	1293	3	operative	operative	JJ
cord-010027-r0tl01kq	1293	4	chemoradiotherapy	chemoradiotherapy	NN
cord-010027-r0tl01kq	1293	5	(	(	-LRB-
cord-010027-r0tl01kq	1293	6	CRT	CRT	NNP
cord-010027-r0tl01kq	1293	7	)	)	-RRB-
cord-010027-r0tl01kq	1293	8	with	with	IN
cord-010027-r0tl01kq	1293	9	anti	anti	JJ
cord-010027-r0tl01kq	1293	10	-	-	JJ
cord-010027-r0tl01kq	1293	11	EGFR	egfr	JJ
cord-010027-r0tl01kq	1293	12	antibodies	antibody	NNS
cord-010027-r0tl01kq	1293	13	may	may	MD
cord-010027-r0tl01kq	1293	14	change	change	VB
cord-010027-r0tl01kq	1293	15	the	the	DT
cord-010027-r0tl01kq	1293	16	status	status	NN
cord-010027-r0tl01kq	1293	17	of	of	IN
cord-010027-r0tl01kq	1293	18	EGFR	EGFR	NNP
cord-010027-r0tl01kq	1293	19	pathway	pathway	NN
cord-010027-r0tl01kq	1293	20	mutations	mutation	NNS
cord-010027-r0tl01kq	1293	21	.	.	.
cord-010027-r0tl01kq	1294	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1294	2	assessed	assess	VBD
cord-010027-r0tl01kq	1294	3	the	the	DT
cord-010027-r0tl01kq	1294	4	mutational	mutational	JJ
cord-010027-r0tl01kq	1294	5	status	status	NN
cord-010027-r0tl01kq	1294	6	of	of	IN
cord-010027-r0tl01kq	1294	7	a	a	DT
cord-010027-r0tl01kq	1294	8	number	number	NN
cord-010027-r0tl01kq	1294	9	of	of	IN
cord-010027-r0tl01kq	1294	10	EGFR	EGFR	NNP
cord-010027-r0tl01kq	1294	11	pathway	pathway	NN
cord-010027-r0tl01kq	1294	12	genes	gene	NNS
cord-010027-r0tl01kq	1294	13	before	before	IN
cord-010027-r0tl01kq	1294	14	and	and	CC
cord-010027-r0tl01kq	1294	15	after	after	IN
cord-010027-r0tl01kq	1294	16	CRT	CRT	NNP
cord-010027-r0tl01kq	1294	17	in	in	IN
cord-010027-r0tl01kq	1294	18	the	the	DT
cord-010027-r0tl01kq	1294	19	NWCOG	NWCOG	NNP
cord-010027-r0tl01kq	1294	20	EXCITE	EXCITE	NNP
cord-010027-r0tl01kq	1294	21	trial	trial	NN
cord-010027-r0tl01kq	1294	22	.	.	.
cord-010027-r0tl01kq	1295	1	Patients	patient	NNS
cord-010027-r0tl01kq	1295	2	with	with	IN
cord-010027-r0tl01kq	1295	3	MRI	MRI	NNP
cord-010027-r0tl01kq	1295	4	-	-	HYPH
cord-010027-r0tl01kq	1295	5	threatened	threaten	VBN
cord-010027-r0tl01kq	1295	6	surgical	surgical	JJ
cord-010027-r0tl01kq	1295	7	margins	margin	NNS
cord-010027-r0tl01kq	1295	8	were	be	VBD
cord-010027-r0tl01kq	1295	9	given	give	VBN
cord-010027-r0tl01kq	1295	10	pelvic	pelvic	JJ
cord-010027-r0tl01kq	1295	11	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1295	12	(	(	-LRB-
cord-010027-r0tl01kq	1295	13	45Gy	45gy	CD
cord-010027-r0tl01kq	1295	14	)	)	-RRB-
cord-010027-r0tl01kq	1295	15	with	with	IN
cord-010027-r0tl01kq	1295	16	capecitabine	capecitabine	NNP
cord-010027-r0tl01kq	1295	17	,	,	,
cord-010027-r0tl01kq	1295	18	irinotecan	irinotecan	NNP
cord-010027-r0tl01kq	1295	19	and	and	CC
cord-010027-r0tl01kq	1295	20	cetuximab	cetuximab	NNP
cord-010027-r0tl01kq	1295	21	followed	follow	VBN
cord-010027-r0tl01kq	1295	22	by	by	IN
cord-010027-r0tl01kq	1295	23	surgery	surgery	NN
cord-010027-r0tl01kq	1295	24	after	after	IN
cord-010027-r0tl01kq	1295	25	8	8	CD
cord-010027-r0tl01kq	1295	26	weeks	week	NNS
cord-010027-r0tl01kq	1295	27	.	.	.
cord-010027-r0tl01kq	1296	1	DNA	DNA	NNP
cord-010027-r0tl01kq	1296	2	was	be	VBD
cord-010027-r0tl01kq	1296	3	retrospectively	retrospectively	RB
cord-010027-r0tl01kq	1296	4	extracted	extract	VBN
cord-010027-r0tl01kq	1296	5	from	from	IN
cord-010027-r0tl01kq	1296	6	the	the	DT
cord-010027-r0tl01kq	1296	7	pre	pre	JJ
cord-010027-r0tl01kq	1296	8	-	-	JJ
cord-010027-r0tl01kq	1296	9	treatment	treatment	JJ
cord-010027-r0tl01kq	1296	10	biopsy	biopsy	NN
cord-010027-r0tl01kq	1296	11	and	and	CC
cord-010027-r0tl01kq	1296	12	resection	resection	NN
cord-010027-r0tl01kq	1296	13	specimen	specimen	NN
cord-010027-r0tl01kq	1296	14	by	by	IN
cord-010027-r0tl01kq	1296	15	macrodissecting	macrodissecte	VBG
cord-010027-r0tl01kq	1296	16	areas	area	NNS
cord-010027-r0tl01kq	1296	17	of	of	IN
cord-010027-r0tl01kq	1296	18	greatest	great	JJS
cord-010027-r0tl01kq	1296	19	residual	residual	JJ
cord-010027-r0tl01kq	1296	20	tumour	tumour	NN
cord-010027-r0tl01kq	1296	21	.	.	.
cord-010027-r0tl01kq	1297	1	The	the	DT
cord-010027-r0tl01kq	1297	2	mutational	mutational	JJ
cord-010027-r0tl01kq	1297	3	status	status	NN
cord-010027-r0tl01kq	1297	4	of	of	IN
cord-010027-r0tl01kq	1297	5	KRAS	KRAS	NNP
cord-010027-r0tl01kq	1297	6	(	(	-LRB-
cord-010027-r0tl01kq	1297	7	codons	codon	NNS
cord-010027-r0tl01kq	1297	8	12/13/61/146	12/13/61/146	CD
cord-010027-r0tl01kq	1297	9	)	)	-RRB-
cord-010027-r0tl01kq	1297	10	,	,	,
cord-010027-r0tl01kq	1297	11	NRAS	NRAS	NNP
cord-010027-r0tl01kq	1297	12	(	(	-LRB-
cord-010027-r0tl01kq	1297	13	12/13/61	12/13/61	CD
cord-010027-r0tl01kq	1297	14	)	)	-RRB-
cord-010027-r0tl01kq	1297	15	,	,	,
cord-010027-r0tl01kq	1297	16	PIK3CA	pik3ca	NN
cord-010027-r0tl01kq	1297	17	(	(	-LRB-
cord-010027-r0tl01kq	1297	18	542/545/546/1047	542/545/546/1047	CD
cord-010027-r0tl01kq	1297	19	)	)	-RRB-
cord-010027-r0tl01kq	1297	20	and	and	CC
cord-010027-r0tl01kq	1297	21	BRAF	BRAF	NNP
cord-010027-r0tl01kq	1297	22	(	(	-LRB-
cord-010027-r0tl01kq	1297	23	V600E	v600e	NN
cord-010027-r0tl01kq	1297	24	hotspot	hotspot	NN
cord-010027-r0tl01kq	1297	25	)	)	-RRB-
cord-010027-r0tl01kq	1297	26	were	be	VBD
cord-010027-r0tl01kq	1297	27	determined	determine	VBN
cord-010027-r0tl01kq	1297	28	by	by	IN
cord-010027-r0tl01kq	1297	29	pyrosequencing	pyrosequence	VBG
cord-010027-r0tl01kq	1297	30	.	.	.
cord-010027-r0tl01kq	1298	1	The	the	DT
cord-010027-r0tl01kq	1298	2	work	work	NN
cord-010027-r0tl01kq	1298	3	is	be	VBZ
cord-010027-r0tl01kq	1298	4	presented	present	VBN
cord-010027-r0tl01kq	1298	5	on	on	IN
cord-010027-r0tl01kq	1298	6	behalf	behalf	NN
cord-010027-r0tl01kq	1298	7	of	of	IN
cord-010027-r0tl01kq	1298	8	the	the	DT
cord-010027-r0tl01kq	1298	9	NWCOG	NWCOG	NNP
cord-010027-r0tl01kq	1298	10	EXCITE	excite	VBP
cord-010027-r0tl01kq	1298	11	trial	trial	NN
cord-010027-r0tl01kq	1298	12	investigators	investigator	NNS
cord-010027-r0tl01kq	1298	13	and	and	CC
cord-010027-r0tl01kq	1298	14	was	be	VBD
cord-010027-r0tl01kq	1298	15	part	part	NN
cord-010027-r0tl01kq	1298	16	-	-	HYPH
cord-010027-r0tl01kq	1298	17	funded	fund	VBN
cord-010027-r0tl01kq	1298	18	by	by	IN
cord-010027-r0tl01kq	1298	19	a	a	DT
cord-010027-r0tl01kq	1298	20	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	1298	21	fellowship	fellowship	NN
cord-010027-r0tl01kq	1298	22	.	.	.
cord-010027-r0tl01kq	1299	1	80	80	CD
cord-010027-r0tl01kq	1299	2	patients	patient	NNS
cord-010027-r0tl01kq	1299	3	commenced	commence	VBD
cord-010027-r0tl01kq	1299	4	treatment	treatment	NN
cord-010027-r0tl01kq	1299	5	and	and	CC
cord-010027-r0tl01kq	1299	6	76	76	CD
cord-010027-r0tl01kq	1299	7	underwent	undergo	VBD
cord-010027-r0tl01kq	1299	8	surgery	surgery	NN
cord-010027-r0tl01kq	1299	9	with	with	IN
cord-010027-r0tl01kq	1299	10	pathological	pathological	JJ
cord-010027-r0tl01kq	1299	11	complete	complete	JJ
cord-010027-r0tl01kq	1299	12	response	response	NN
cord-010027-r0tl01kq	1299	13	in	in	IN
cord-010027-r0tl01kq	1299	14	14	14	CD
cord-010027-r0tl01kq	1299	15	(	(	-LRB-
cord-010027-r0tl01kq	1299	16	18	18	CD
cord-010027-r0tl01kq	1299	17	%	%	NN
cord-010027-r0tl01kq	1299	18	)	)	-RRB-
cord-010027-r0tl01kq	1299	19	and	and	CC
cord-010027-r0tl01kq	1299	20	near	near	RB
cord-010027-r0tl01kq	1299	21	-	-	HYPH
cord-010027-r0tl01kq	1299	22	complete	complete	JJ
cord-010027-r0tl01kq	1299	23	in	in	IN
cord-010027-r0tl01kq	1299	24	6	6	CD
cord-010027-r0tl01kq	1299	25	(	(	-LRB-
cord-010027-r0tl01kq	1299	26	8	8	CD
cord-010027-r0tl01kq	1299	27	%	%	NN
cord-010027-r0tl01kq	1299	28	)	)	-RRB-
cord-010027-r0tl01kq	1299	29	.	.	.
cord-010027-r0tl01kq	1300	1	Pre	pre	JJ
cord-010027-r0tl01kq	1300	2	-	-	JJ
cord-010027-r0tl01kq	1300	3	treatment	treatment	JJ
cord-010027-r0tl01kq	1300	4	testing	testing	NN
cord-010027-r0tl01kq	1300	5	(	(	-LRB-
cord-010027-r0tl01kq	1300	6	n=78	n=78	NN
cord-010027-r0tl01kq	1300	7	)	)	-RRB-
cord-010027-r0tl01kq	1300	8	detected	detect	VBN
cord-010027-r0tl01kq	1300	9	mutations	mutation	NNS
cord-010027-r0tl01kq	1300	10	in	in	IN
cord-010027-r0tl01kq	1300	11	KRAS	KRAS	NNP
cord-010027-r0tl01kq	1300	12	(	(	-LRB-
cord-010027-r0tl01kq	1300	13	n=34	n=34	NNP
cord-010027-r0tl01kq	1300	14	)	)	-RRB-
cord-010027-r0tl01kq	1300	15	,	,	,
cord-010027-r0tl01kq	1300	16	BRAF	BRAF	NNP
cord-010027-r0tl01kq	1300	17	(	(	-LRB-
cord-010027-r0tl01kq	1300	18	n=3	n=3	NN
cord-010027-r0tl01kq	1300	19	)	)	-RRB-
cord-010027-r0tl01kq	1300	20	,	,	,
cord-010027-r0tl01kq	1300	21	NRAS	NRAS	NNP
cord-010027-r0tl01kq	1300	22	(	(	-LRB-
cord-010027-r0tl01kq	1300	23	n=3	n=3	NN
cord-010027-r0tl01kq	1300	24	)	)	-RRB-
cord-010027-r0tl01kq	1300	25	and	and	CC
cord-010027-r0tl01kq	1300	26	PIK3CA	PIK3CA	NNP
cord-010027-r0tl01kq	1300	27	(	(	-LRB-
cord-010027-r0tl01kq	1300	28	n=10	n=10	NNP
cord-010027-r0tl01kq	1300	29	)	)	-RRB-
cord-010027-r0tl01kq	1300	30	.	.	.
cord-010027-r0tl01kq	1301	1	Any	any	DT
cord-010027-r0tl01kq	1301	2	EGFR	EGFR	NNP
cord-010027-r0tl01kq	1301	3	pathway	pathway	NN
cord-010027-r0tl01kq	1301	4	mutation	mutation	NN
cord-010027-r0tl01kq	1301	5	was	be	VBD
cord-010027-r0tl01kq	1301	6	detected	detect	VBN
cord-010027-r0tl01kq	1301	7	in	in	IN
cord-010027-r0tl01kq	1301	8	58	58	CD
cord-010027-r0tl01kq	1301	9	%	%	NN
cord-010027-r0tl01kq	1301	10	.	.	.
cord-010027-r0tl01kq	1302	1	Following	follow	VBG
cord-010027-r0tl01kq	1302	2	CRT	CRT	NNP
cord-010027-r0tl01kq	1302	3	,	,	,
cord-010027-r0tl01kq	1302	4	cases	case	NNS
cord-010027-r0tl01kq	1302	5	with	with	IN
cord-010027-r0tl01kq	1302	6	residual	residual	JJ
cord-010027-r0tl01kq	1302	7	tumour	tumour	NN
cord-010027-r0tl01kq	1302	8	able	able	JJ
cord-010027-r0tl01kq	1302	9	to	to	TO
cord-010027-r0tl01kq	1302	10	be	be	VB
cord-010027-r0tl01kq	1302	11	tested	test	VBN
cord-010027-r0tl01kq	1302	12	(	(	-LRB-
cord-010027-r0tl01kq	1302	13	n=54	n=54	JJ
cord-010027-r0tl01kq	1302	14	)	)	-RRB-
cord-010027-r0tl01kq	1302	15	showed	show	VBD
cord-010027-r0tl01kq	1302	16	mutations	mutation	NNS
cord-010027-r0tl01kq	1302	17	in	in	IN
cord-010027-r0tl01kq	1302	18	32	32	CD
cord-010027-r0tl01kq	1302	19	patients	patient	NNS
cord-010027-r0tl01kq	1302	20	(	(	-LRB-
cord-010027-r0tl01kq	1302	21	59	59	CD
cord-010027-r0tl01kq	1302	22	%	%	NN
cord-010027-r0tl01kq	1302	23	)	)	-RRB-
cord-010027-r0tl01kq	1302	24	.	.	.
cord-010027-r0tl01kq	1303	1	There	there	EX
cord-010027-r0tl01kq	1303	2	was	be	VBD
cord-010027-r0tl01kq	1303	3	a	a	DT
cord-010027-r0tl01kq	1303	4	discrepancy	discrepancy	NN
cord-010027-r0tl01kq	1303	5	compared	compare	VBN
cord-010027-r0tl01kq	1303	6	to	to	IN
cord-010027-r0tl01kq	1303	7	pre	pre	JJ
cord-010027-r0tl01kq	1303	8	-	-	JJ
cord-010027-r0tl01kq	1303	9	treatment	treatment	JJ
cord-010027-r0tl01kq	1303	10	biopsy	biopsy	NN
cord-010027-r0tl01kq	1303	11	in	in	IN
cord-010027-r0tl01kq	1303	12	18	18	CD
cord-010027-r0tl01kq	1303	13	cases	case	NNS
cord-010027-r0tl01kq	1303	14	(	(	-LRB-
cord-010027-r0tl01kq	1303	15	33	33	CD
cord-010027-r0tl01kq	1303	16	%	%	NN
cord-010027-r0tl01kq	1303	17	)	)	-RRB-
cord-010027-r0tl01kq	1303	18	:	:	:
cord-010027-r0tl01kq	1303	19	from	from	IN
cord-010027-r0tl01kq	1303	20	wild	wild	JJ
cord-010027-r0tl01kq	1303	21	-	-	HYPH
cord-010027-r0tl01kq	1303	22	type	type	NN
cord-010027-r0tl01kq	1303	23	(	(	-LRB-
cord-010027-r0tl01kq	1303	24	wt	wt	NN
cord-010027-r0tl01kq	1303	25	)	)	-RRB-
cord-010027-r0tl01kq	1303	26	to	to	IN
cord-010027-r0tl01kq	1303	27	mutant	mutant	JJ
cord-010027-r0tl01kq	1303	28	(	(	-LRB-
cord-010027-r0tl01kq	1303	29	mut	mut	NNP
cord-010027-r0tl01kq	1303	30	)	)	-RRB-
cord-010027-r0tl01kq	1303	31	in	in	IN
cord-010027-r0tl01kq	1303	32	9	9	CD
cord-010027-r0tl01kq	1303	33	,	,	,
cord-010027-r0tl01kq	1303	34	from	from	IN
cord-010027-r0tl01kq	1303	35	mut	mut	NNP
cord-010027-r0tl01kq	1303	36	to	to	IN
cord-010027-r0tl01kq	1303	37	different	different	JJ
cord-010027-r0tl01kq	1303	38	mut	mut	NN
cord-010027-r0tl01kq	1303	39	in	in	IN
cord-010027-r0tl01kq	1303	40	1	1	CD
cord-010027-r0tl01kq	1303	41	and	and	CC
cord-010027-r0tl01kq	1303	42	from	from	IN
cord-010027-r0tl01kq	1303	43	mut	mut	NNP
cord-010027-r0tl01kq	1303	44	to	to	TO
cord-010027-r0tl01kq	1303	45	wt	wt	VB
cord-010027-r0tl01kq	1303	46	in	in	IN
cord-010027-r0tl01kq	1303	47	7	7	CD
cord-010027-r0tl01kq	1303	48	.	.	.
cord-010027-r0tl01kq	1304	1	One	one	CD
cord-010027-r0tl01kq	1304	2	patient	patient	NN
cord-010027-r0tl01kq	1304	3	changed	change	VBD
cord-010027-r0tl01kq	1304	4	in	in	IN
cord-010027-r0tl01kq	1304	5	3	3	CD
cord-010027-r0tl01kq	1304	6	codons	codon	NNS
cord-010027-r0tl01kq	1304	7	(	(	-LRB-
cord-010027-r0tl01kq	1304	8	mut	mut	NNP
cord-010027-r0tl01kq	1304	9	to	to	TO
cord-010027-r0tl01kq	1304	10	wt	wt	VB
cord-010027-r0tl01kq	1304	11	in	in	IN
cord-010027-r0tl01kq	1304	12	KRAS	KRAS	NNP
cord-010027-r0tl01kq	1304	13	146	146	CD
cord-010027-r0tl01kq	1305	1	/PIK3CA	/PIK3CA	NNP
cord-010027-r0tl01kq	1305	2	545	545	CD
cord-010027-r0tl01kq	1305	3	and	and	CC
cord-010027-r0tl01kq	1305	4	wt	wt	NN
cord-010027-r0tl01kq	1305	5	to	to	TO
cord-010027-r0tl01kq	1305	6	mut	mut	VB
cord-010027-r0tl01kq	1305	7	in	in	IN
cord-010027-r0tl01kq	1305	8	KRAS	KRAS	NNP
cord-010027-r0tl01kq	1305	9	12	12	CD
cord-010027-r0tl01kq	1305	10	)	)	-RRB-
cord-010027-r0tl01kq	1305	11	.	.	.
cord-010027-r0tl01kq	1306	1	In	in	IN
cord-010027-r0tl01kq	1306	2	12	12	CD
cord-010027-r0tl01kq	1306	3	patients	patient	NNS
cord-010027-r0tl01kq	1306	4	(	(	-LRB-
cord-010027-r0tl01kq	1306	5	22	22	CD
cord-010027-r0tl01kq	1306	6	%	%	NN
cord-010027-r0tl01kq	1306	7	)	)	-RRB-
cord-010027-r0tl01kq	1306	8	this	this	DT
cord-010027-r0tl01kq	1306	9	changed	change	VBD
cord-010027-r0tl01kq	1306	10	their	-PRON-	PRP$
cord-010027-r0tl01kq	1306	11	overall	overall	JJ
cord-010027-r0tl01kq	1306	12	EGFR	EGFR	NNP
cord-010027-r0tl01kq	1306	13	pathway	pathway	NN
cord-010027-r0tl01kq	1306	14	status	status	NN
cord-010027-r0tl01kq	1306	15	(	(	-LRB-
cord-010027-r0tl01kq	1306	16	6x	6x	CD
cord-010027-r0tl01kq	1306	17	wt	wt	NN
cord-010027-r0tl01kq	1306	18	to	to	IN
cord-010027-r0tl01kq	1306	19	mut	mut	NNP
cord-010027-r0tl01kq	1306	20	and	and	CC
cord-010027-r0tl01kq	1306	21	6x	6x	CD
cord-010027-r0tl01kq	1306	22	mut	mut	NNP
cord-010027-r0tl01kq	1306	23	to	to	TO
cord-010027-r0tl01kq	1306	24	wt	wt	VB
cord-010027-r0tl01kq	1306	25	)	)	-RRB-
cord-010027-r0tl01kq	1306	26	.	.	.
cord-010027-r0tl01kq	1307	1	Intratumour	Intratumour	NNP
cord-010027-r0tl01kq	1307	2	heterogeneity	heterogeneity	NN
cord-010027-r0tl01kq	1307	3	may	may	MD
cord-010027-r0tl01kq	1307	4	explain	explain	VB
cord-010027-r0tl01kq	1307	5	some	some	DT
cord-010027-r0tl01kq	1307	6	of	of	IN
cord-010027-r0tl01kq	1307	7	the	the	DT
cord-010027-r0tl01kq	1307	8	differences	difference	NNS
cord-010027-r0tl01kq	1307	9	in	in	IN
cord-010027-r0tl01kq	1307	10	EGFR	EGFR	NNP
cord-010027-r0tl01kq	1307	11	pathway	pathway	NN
cord-010027-r0tl01kq	1307	12	mutations	mutation	NNS
cord-010027-r0tl01kq	1307	13	reported	report	VBN
cord-010027-r0tl01kq	1307	14	between	between	IN
cord-010027-r0tl01kq	1307	15	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1307	16	and	and	CC
cord-010027-r0tl01kq	1307	17	resections	resection	NNS
cord-010027-r0tl01kq	1307	18	presenting	present	VBG
cord-010027-r0tl01kq	1307	19	a	a	DT
cord-010027-r0tl01kq	1307	20	challenge	challenge	NN
cord-010027-r0tl01kq	1307	21	to	to	IN
cord-010027-r0tl01kq	1307	22	personalised	personalised	JJ
cord-010027-r0tl01kq	1307	23	medicine	medicine	NN
cord-010027-r0tl01kq	1307	24	.	.	.
cord-010027-r0tl01kq	1308	1	However	however	RB
cord-010027-r0tl01kq	1308	2	,	,	,
cord-010027-r0tl01kq	1308	3	cetuximab	cetuximab	NNP
cord-010027-r0tl01kq	1308	4	may	may	MD
cord-010027-r0tl01kq	1308	5	also	also	RB
cord-010027-r0tl01kq	1308	6	drive	drive	VB
cord-010027-r0tl01kq	1308	7	the	the	DT
cord-010027-r0tl01kq	1308	8	growth	growth	NN
cord-010027-r0tl01kq	1308	9	of	of	IN
cord-010027-r0tl01kq	1308	10	undetectable	undetectable	JJ
cord-010027-r0tl01kq	1308	11	mutant	mutant	JJ
cord-010027-r0tl01kq	1308	12	clones	clone	NNS
cord-010027-r0tl01kq	1308	13	to	to	IN
cord-010027-r0tl01kq	1308	14	detectable	detectable	JJ
cord-010027-r0tl01kq	1308	15	levels	level	NNS
cord-010027-r0tl01kq	1308	16	on	on	IN
cord-010027-r0tl01kq	1308	17	pyrosequencing	pyrosequencing	NN
cord-010027-r0tl01kq	1308	18	.	.	.
cord-010027-r0tl01kq	1309	1	Further	further	JJ
cord-010027-r0tl01kq	1309	2	assessment	assessment	NN
cord-010027-r0tl01kq	1309	3	using	use	VBG
cord-010027-r0tl01kq	1309	4	more	more	RBR
cord-010027-r0tl01kq	1309	5	sensitive	sensitive	JJ
cord-010027-r0tl01kq	1309	6	sequencing	sequencing	NN
cord-010027-r0tl01kq	1309	7	technologies	technology	NNS
cord-010027-r0tl01kq	1309	8	is	be	VBZ
cord-010027-r0tl01kq	1309	9	currently	currently	RB
cord-010027-r0tl01kq	1309	10	being	be	VBG
cord-010027-r0tl01kq	1309	11	employed	employ	VBN
cord-010027-r0tl01kq	1309	12	to	to	TO
cord-010027-r0tl01kq	1309	13	investigate	investigate	VB
cord-010027-r0tl01kq	1309	14	these	these	DT
cord-010027-r0tl01kq	1309	15	differences	difference	NNS
cord-010027-r0tl01kq	1309	16	.	.	.
cord-010027-r0tl01kq	1310	1	There	there	EX
cord-010027-r0tl01kq	1310	2	is	be	VBZ
cord-010027-r0tl01kq	1310	3	a	a	DT
cord-010027-r0tl01kq	1310	4	vast	vast	JJ
cord-010027-r0tl01kq	1310	5	amount	amount	NN
cord-010027-r0tl01kq	1310	6	of	of	IN
cord-010027-r0tl01kq	1310	7	historical	historical	JJ
cord-010027-r0tl01kq	1310	8	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1310	9	material	material	NN
cord-010027-r0tl01kq	1310	10	held	hold	VBN
cord-010027-r0tl01kq	1310	11	in	in	IN
cord-010027-r0tl01kq	1310	12	archives	archive	NNS
cord-010027-r0tl01kq	1310	13	,	,	,
cord-010027-r0tl01kq	1310	14	but	but	CC
cord-010027-r0tl01kq	1310	15	due	due	IN
cord-010027-r0tl01kq	1310	16	to	to	IN
cord-010027-r0tl01kq	1310	17	variations	variation	NNS
cord-010027-r0tl01kq	1310	18	in	in	IN
cord-010027-r0tl01kq	1310	19	fixation	fixation	NN
cord-010027-r0tl01kq	1310	20	and	and	CC
cord-010027-r0tl01kq	1310	21	processing	process	VBG
cord-010027-r0tl01kq	1310	22	this	this	DT
cord-010027-r0tl01kq	1310	23	presents	present	VBZ
cord-010027-r0tl01kq	1310	24	several	several	JJ
cord-010027-r0tl01kq	1310	25	challenges	challenge	NNS
cord-010027-r0tl01kq	1310	26	when	when	WRB
cord-010027-r0tl01kq	1310	27	applying	apply	VBG
cord-010027-r0tl01kq	1310	28	newer	new	JJR
cord-010027-r0tl01kq	1310	29	genomic	genomic	JJ
cord-010027-r0tl01kq	1310	30	technologies	technology	NNS
cord-010027-r0tl01kq	1310	31	to	to	IN
cord-010027-r0tl01kq	1310	32	it	-PRON-	PRP
cord-010027-r0tl01kq	1310	33	.	.	.
cord-010027-r0tl01kq	1311	1	In	in	IN
cord-010027-r0tl01kq	1311	2	this	this	DT
cord-010027-r0tl01kq	1311	3	study	study	NN
cord-010027-r0tl01kq	1311	4	we	-PRON-	PRP
cord-010027-r0tl01kq	1311	5	compared	compare	VBD
cord-010027-r0tl01kq	1311	6	the	the	DT
cord-010027-r0tl01kq	1311	7	genomic	genomic	JJ
cord-010027-r0tl01kq	1311	8	information	information	NN
cord-010027-r0tl01kq	1311	9	obtained	obtain	VBN
cord-010027-r0tl01kq	1311	10	with	with	IN
cord-010027-r0tl01kq	1311	11	the	the	DT
cord-010027-r0tl01kq	1311	12	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1311	13	®	®	NNP
cord-010027-r0tl01kq	1311	14	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1311	15	Assay	Assay	NNP
cord-010027-r0tl01kq	1311	16	Kit	kit	NN
cord-010027-r0tl01kq	1311	17	(	(	-LRB-
cord-010027-r0tl01kq	1311	18	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1311	19	)	)	-RRB-
cord-010027-r0tl01kq	1311	20	and	and	CC
cord-010027-r0tl01kq	1311	21	next	next	JJ
cord-010027-r0tl01kq	1311	22	generation	generation	NN
cord-010027-r0tl01kq	1311	23	sequencing	sequencing	NN
cord-010027-r0tl01kq	1311	24	(	(	-LRB-
cord-010027-r0tl01kq	1311	25	NGS	NGS	NNP
cord-010027-r0tl01kq	1311	26	)	)	-RRB-
cord-010027-r0tl01kq	1311	27	.	.	.
cord-010027-r0tl01kq	1312	1	Samples	sample	NNS
cord-010027-r0tl01kq	1312	2	from	from	IN
cord-010027-r0tl01kq	1312	3	378	378	CD
cord-010027-r0tl01kq	1312	4	patients	patient	NNS
cord-010027-r0tl01kq	1312	5	were	be	VBD
cord-010027-r0tl01kq	1312	6	obtained	obtain	VBN
cord-010027-r0tl01kq	1312	7	from	from	IN
cord-010027-r0tl01kq	1312	8	10	10	CD
cord-010027-r0tl01kq	1312	9	centres	centre	NNS
cord-010027-r0tl01kq	1312	10	taking	take	VBG
cord-010027-r0tl01kq	1312	11	part	part	NN
cord-010027-r0tl01kq	1312	12	in	in	IN
cord-010027-r0tl01kq	1312	13	the	the	DT
cord-010027-r0tl01kq	1312	14	MRC	MRC	NNP
cord-010027-r0tl01kq	1312	15	CR07	CR07	NNP
cord-010027-r0tl01kq	1312	16	trial	trial	NN
cord-010027-r0tl01kq	1312	17	of	of	IN
cord-010027-r0tl01kq	1312	18	short	short	JJ
cord-010027-r0tl01kq	1312	19	course	course	NN
cord-010027-r0tl01kq	1312	20	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1312	21	versus	versus	IN
cord-010027-r0tl01kq	1312	22	selective	selective	JJ
cord-010027-r0tl01kq	1312	23	long	long	JJ
cord-010027-r0tl01kq	1312	24	course	course	NN
cord-010027-r0tl01kq	1312	25	chemoradiotherapy	chemoradiotherapy	NN
cord-010027-r0tl01kq	1312	26	in	in	IN
cord-010027-r0tl01kq	1312	27	rectal	rectal	JJ
cord-010027-r0tl01kq	1312	28	cancer	cancer	NN
cord-010027-r0tl01kq	1312	29	.	.	.
cord-010027-r0tl01kq	1313	1	DNA	DNA	NNP
cord-010027-r0tl01kq	1313	2	was	be	VBD
cord-010027-r0tl01kq	1313	3	prepared	prepare	VBN
cord-010027-r0tl01kq	1313	4	using	use	VBG
cord-010027-r0tl01kq	1313	5	Agilent	Agilent	NNP
cord-010027-r0tl01kq	1313	6	SureSelect	SureSelect	NNP
cord-010027-r0tl01kq	1313	7	kits	kit	NNS
cord-010027-r0tl01kq	1313	8	and	and	CC
cord-010027-r0tl01kq	1313	9	sequenced	sequence	VBN
cord-010027-r0tl01kq	1313	10	using	use	VBG
cord-010027-r0tl01kq	1313	11	Illumina	Illumina	NNP
cord-010027-r0tl01kq	1313	12	platforms	platform	NNS
cord-010027-r0tl01kq	1313	13	in	in	IN
cord-010027-r0tl01kq	1313	14	parallel	parallel	NN
cord-010027-r0tl01kq	1313	15	to	to	IN
cord-010027-r0tl01kq	1313	16	analysis	analysis	NN
cord-010027-r0tl01kq	1313	17	using	use	VBG
cord-010027-r0tl01kq	1313	18	the	the	DT
cord-010027-r0tl01kq	1313	19	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1313	20	assay	assay	NN
cord-010027-r0tl01kq	1313	21	.	.	.
cord-010027-r0tl01kq	1314	1	For	for	IN
cord-010027-r0tl01kq	1314	2	both	both	DT
cord-010027-r0tl01kq	1314	3	methods	method	NNS
cord-010027-r0tl01kq	1314	4	,	,	,
cord-010027-r0tl01kq	1314	5	quality	quality	NN
cord-010027-r0tl01kq	1314	6	control	control	NN
cord-010027-r0tl01kq	1314	7	(	(	-LRB-
cord-010027-r0tl01kq	1314	8	QC	QC	NNP
cord-010027-r0tl01kq	1314	9	)	)	-RRB-
cord-010027-r0tl01kq	1314	10	data	datum	NNS
cord-010027-r0tl01kq	1314	11	was	be	VBD
cord-010027-r0tl01kq	1314	12	generated	generate	VBN
cord-010027-r0tl01kq	1314	13	and	and	CC
cord-010027-r0tl01kq	1314	14	the	the	DT
cord-010027-r0tl01kq	1314	15	sample	sample	NN
cord-010027-r0tl01kq	1314	16	classified	classify	VBN
cord-010027-r0tl01kq	1314	17	as	as	IN
cord-010027-r0tl01kq	1314	18	a	a	DT
cord-010027-r0tl01kq	1314	19	'	'	``
cord-010027-r0tl01kq	1314	20	pass	pass	NN
cord-010027-r0tl01kq	1314	21	'	'	''
cord-010027-r0tl01kq	1314	22	if	if	IN
cord-010027-r0tl01kq	1314	23	it	-PRON-	PRP
cord-010027-r0tl01kq	1314	24	fell	fall	VBD
cord-010027-r0tl01kq	1314	25	within	within	IN
cord-010027-r0tl01kq	1314	26	the	the	DT
cord-010027-r0tl01kq	1314	27	pre	pre	NN
cord-010027-r0tl01kq	1314	28	-	-	JJ
cord-010027-r0tl01kq	1314	29	defined	define	VBN
cord-010027-r0tl01kq	1314	30	QC	QC	NNP
cord-010027-r0tl01kq	1314	31	boundaries	boundary	NNS
cord-010027-r0tl01kq	1314	32	.	.	.
cord-010027-r0tl01kq	1315	1	For	for	IN
cord-010027-r0tl01kq	1315	2	the	the	DT
cord-010027-r0tl01kq	1315	3	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1315	4	assay	assay	NN
cord-010027-r0tl01kq	1315	5	,	,	,
cord-010027-r0tl01kq	1315	6	copy	copy	NN
cord-010027-r0tl01kq	1315	7	number	number	NN
cord-010027-r0tl01kq	1315	8	(	(	-LRB-
cord-010027-r0tl01kq	1315	9	CN	CN	NNP
cord-010027-r0tl01kq	1315	10	)	)	-RRB-
cord-010027-r0tl01kq	1315	11	and	and	CC
cord-010027-r0tl01kq	1315	12	somatic	somatic	JJ
cord-010027-r0tl01kq	1315	13	mutation	mutation	NN
cord-010027-r0tl01kq	1315	14	(	(	-LRB-
cord-010027-r0tl01kq	1315	15	SM	SM	NNP
cord-010027-r0tl01kq	1315	16	)	)	-RRB-
cord-010027-r0tl01kq	1315	17	data	datum	NNS
cord-010027-r0tl01kq	1315	18	was	be	VBD
cord-010027-r0tl01kq	1315	19	further	further	RB
cord-010027-r0tl01kq	1315	20	investigated	investigate	VBN
cord-010027-r0tl01kq	1315	21	.	.	.
cord-010027-r0tl01kq	1316	1	This	this	DT
cord-010027-r0tl01kq	1316	2	study	study	NN
cord-010027-r0tl01kq	1316	3	was	be	VBD
cord-010027-r0tl01kq	1316	4	part	part	NN
cord-010027-r0tl01kq	1316	5	funded	fund	VBN
cord-010027-r0tl01kq	1316	6	by	by	IN
cord-010027-r0tl01kq	1316	7	a	a	DT
cord-010027-r0tl01kq	1316	8	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	1316	9	Fellowship	Fellowship	NNP
cord-010027-r0tl01kq	1316	10	.	.	.
cord-010027-r0tl01kq	1317	1	In	in	IN
cord-010027-r0tl01kq	1317	2	total	total	JJ
cord-010027-r0tl01kq	1317	3	,	,	,
cord-010027-r0tl01kq	1317	4	272	272	CD
cord-010027-r0tl01kq	1317	5	cases	case	NNS
cord-010027-r0tl01kq	1317	6	(	(	-LRB-
cord-010027-r0tl01kq	1317	7	72	72	CD
cord-010027-r0tl01kq	1317	8	%	%	NN
cord-010027-r0tl01kq	1317	9	)	)	-RRB-
cord-010027-r0tl01kq	1317	10	passed	pass	VBD
cord-010027-r0tl01kq	1317	11	the	the	DT
cord-010027-r0tl01kq	1317	12	NGS	NGS	NNP
cord-010027-r0tl01kq	1317	13	QC	QC	NNP
cord-010027-r0tl01kq	1317	14	and	and	CC
cord-010027-r0tl01kq	1317	15	232	232	CD
cord-010027-r0tl01kq	1317	16	(	(	-LRB-
cord-010027-r0tl01kq	1317	17	61	61	CD
cord-010027-r0tl01kq	1317	18	%	%	NN
cord-010027-r0tl01kq	1317	19	)	)	-RRB-
cord-010027-r0tl01kq	1317	20	passed	pass	VBD
cord-010027-r0tl01kq	1317	21	the	the	DT
cord-010027-r0tl01kq	1317	22	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1317	23	QC	QC	NNP
cord-010027-r0tl01kq	1317	24	.	.	.
cord-010027-r0tl01kq	1318	1	A	a	DT
cord-010027-r0tl01kq	1318	2	total	total	NN
cord-010027-r0tl01kq	1318	3	of	of	IN
cord-010027-r0tl01kq	1318	4	186	186	CD
cord-010027-r0tl01kq	1318	5	(	(	-LRB-
cord-010027-r0tl01kq	1318	6	49	49	CD
cord-010027-r0tl01kq	1318	7	%	%	NN
cord-010027-r0tl01kq	1318	8	)	)	-RRB-
cord-010027-r0tl01kq	1318	9	passed	pass	VBD
cord-010027-r0tl01kq	1318	10	QC	QC	NNP
cord-010027-r0tl01kq	1318	11	on	on	IN
cord-010027-r0tl01kq	1318	12	both	both	DT
cord-010027-r0tl01kq	1318	13	platforms	platform	NNS
cord-010027-r0tl01kq	1318	14	with	with	IN
cord-010027-r0tl01kq	1318	15	marked	marked	JJ
cord-010027-r0tl01kq	1318	16	variability	variability	NN
cord-010027-r0tl01kq	1318	17	in	in	IN
cord-010027-r0tl01kq	1318	18	sample	sample	NN
cord-010027-r0tl01kq	1318	19	pass	pass	NN
cord-010027-r0tl01kq	1318	20	rates	rate	NNS
cord-010027-r0tl01kq	1318	21	between	between	IN
cord-010027-r0tl01kq	1318	22	the	the	DT
cord-010027-r0tl01kq	1318	23	10	10	CD
cord-010027-r0tl01kq	1318	24	centres	centre	NNS
cord-010027-r0tl01kq	1318	25	for	for	IN
cord-010027-r0tl01kq	1318	26	the	the	DT
cord-010027-r0tl01kq	1318	27	NGS	NGS	NNP
cord-010027-r0tl01kq	1318	28	(	(	-LRB-
cord-010027-r0tl01kq	1318	29	range	range	NN
cord-010027-r0tl01kq	1318	30	0	0	CD
cord-010027-r0tl01kq	1318	31	%	%	NN
cord-010027-r0tl01kq	1318	32	to	to	TO
cord-010027-r0tl01kq	1318	33	100	100	CD
cord-010027-r0tl01kq	1318	34	%	%	NN
cord-010027-r0tl01kq	1318	35	)	)	-RRB-
cord-010027-r0tl01kq	1318	36	and	and	CC
cord-010027-r0tl01kq	1318	37	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1318	38	(	(	-LRB-
cord-010027-r0tl01kq	1318	39	ranges	range	VBZ
cord-010027-r0tl01kq	1318	40	33	33	CD
cord-010027-r0tl01kq	1318	41	%	%	NN
cord-010027-r0tl01kq	1318	42	to	to	IN
cord-010027-r0tl01kq	1318	43	84	84	CD
cord-010027-r0tl01kq	1318	44	%	%	NN
cord-010027-r0tl01kq	1318	45	)	)	-RRB-
cord-010027-r0tl01kq	1318	46	.	.	.
cord-010027-r0tl01kq	1319	1	When	when	WRB
cord-010027-r0tl01kq	1319	2	assessed	assess	VBN
cord-010027-r0tl01kq	1319	3	manually	manually	RB
cord-010027-r0tl01kq	1319	4	,	,	,
cord-010027-r0tl01kq	1319	5	the	the	DT
cord-010027-r0tl01kq	1319	6	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1319	7	SM	SM	NNP
cord-010027-r0tl01kq	1319	8	data	datum	NNS
cord-010027-r0tl01kq	1319	9	was	be	VBD
cord-010027-r0tl01kq	1319	10	considered	consider	VBN
cord-010027-r0tl01kq	1319	11	acceptable	acceptable	JJ
cord-010027-r0tl01kq	1319	12	for	for	IN
cord-010027-r0tl01kq	1319	13	273	273	CD
cord-010027-r0tl01kq	1319	14	cases	case	NNS
cord-010027-r0tl01kq	1319	15	(	(	-LRB-
cord-010027-r0tl01kq	1319	16	72	72	CD
cord-010027-r0tl01kq	1319	17	%	%	NN
cord-010027-r0tl01kq	1319	18	)	)	-RRB-
cord-010027-r0tl01kq	1319	19	,	,	,
cord-010027-r0tl01kq	1319	20	which	which	WDT
cord-010027-r0tl01kq	1319	21	included	include	VBD
cord-010027-r0tl01kq	1319	22	40	40	CD
cord-010027-r0tl01kq	1319	23	initially	initially	RB
cord-010027-r0tl01kq	1319	24	classified	classify	VBN
cord-010027-r0tl01kq	1319	25	as	as	IN
cord-010027-r0tl01kq	1319	26	'	'	``
cord-010027-r0tl01kq	1319	27	failed	fail	VBD
cord-010027-r0tl01kq	1319	28	'	'	''
cord-010027-r0tl01kq	1319	29	by	by	IN
cord-010027-r0tl01kq	1319	30	the	the	DT
cord-010027-r0tl01kq	1319	31	QC	QC	NNP
cord-010027-r0tl01kq	1319	32	data	datum	NNS
cord-010027-r0tl01kq	1319	33	.	.	.
cord-010027-r0tl01kq	1320	1	Similarly	similarly	RB
cord-010027-r0tl01kq	1320	2	,	,	,
cord-010027-r0tl01kq	1320	3	the	the	DT
cord-010027-r0tl01kq	1320	4	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1320	5	CNV	CNV	NNP
cord-010027-r0tl01kq	1320	6	data	datum	NNS
cord-010027-r0tl01kq	1320	7	was	be	VBD
cord-010027-r0tl01kq	1320	8	interpretable	interpretable	JJ
cord-010027-r0tl01kq	1320	9	for	for	IN
cord-010027-r0tl01kq	1320	10	the	the	DT
cord-010027-r0tl01kq	1320	11	majority	majority	NN
cord-010027-r0tl01kq	1320	12	of	of	IN
cord-010027-r0tl01kq	1320	13	cases	case	NNS
cord-010027-r0tl01kq	1320	14	.	.	.
cord-010027-r0tl01kq	1321	1	This	this	DT
cord-010027-r0tl01kq	1321	2	study	study	NN
cord-010027-r0tl01kq	1321	3	has	have	VBZ
cord-010027-r0tl01kq	1321	4	shown	show	VBN
cord-010027-r0tl01kq	1321	5	that	that	IN
cord-010027-r0tl01kq	1321	6	whilst	whilst	IN
cord-010027-r0tl01kq	1321	7	historical	historical	JJ
cord-010027-r0tl01kq	1321	8	DNA	dna	NN
cord-010027-r0tl01kq	1321	9	held	hold	VBN
cord-010027-r0tl01kq	1321	10	in	in	IN
cord-010027-r0tl01kq	1321	11	the	the	DT
cord-010027-r0tl01kq	1321	12	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1321	13	blocks	block	NNS
cord-010027-r0tl01kq	1321	14	of	of	IN
cord-010027-r0tl01kq	1321	15	archival	archival	JJ
cord-010027-r0tl01kq	1321	16	clinical	clinical	JJ
cord-010027-r0tl01kq	1321	17	trials	trial	NNS
cord-010027-r0tl01kq	1321	18	like	like	IN
cord-010027-r0tl01kq	1321	19	MRC	MRC	NNP
cord-010027-r0tl01kq	1321	20	CR07	CR07	NNP
cord-010027-r0tl01kq	1321	21	can	can	MD
cord-010027-r0tl01kq	1321	22	present	present	VB
cord-010027-r0tl01kq	1321	23	challenges	challenge	NNS
cord-010027-r0tl01kq	1321	24	when	when	WRB
cord-010027-r0tl01kq	1321	25	using	use	VBG
cord-010027-r0tl01kq	1321	26	new	new	JJ
cord-010027-r0tl01kq	1321	27	genomic	genomic	JJ
cord-010027-r0tl01kq	1321	28	technologies	technology	NNS
cord-010027-r0tl01kq	1321	29	,	,	,
cord-010027-r0tl01kq	1321	30	a	a	DT
cord-010027-r0tl01kq	1321	31	large	large	JJ
cord-010027-r0tl01kq	1321	32	proportion	proportion	NN
cord-010027-r0tl01kq	1321	33	of	of	IN
cord-010027-r0tl01kq	1321	34	samples	sample	NNS
cord-010027-r0tl01kq	1321	35	can	can	MD
cord-010027-r0tl01kq	1321	36	still	still	RB
cord-010027-r0tl01kq	1321	37	yield	yield	VB
cord-010027-r0tl01kq	1321	38	valuable	valuable	JJ
cord-010027-r0tl01kq	1321	39	genomic	genomic	JJ
cord-010027-r0tl01kq	1321	40	data	datum	NNS
cord-010027-r0tl01kq	1321	41	.	.	.
cord-010027-r0tl01kq	1322	1	Marked	marked	JJ
cord-010027-r0tl01kq	1322	2	variation	variation	NN
cord-010027-r0tl01kq	1322	3	exists	exist	VBZ
cord-010027-r0tl01kq	1322	4	in	in	IN
cord-010027-r0tl01kq	1322	5	the	the	DT
cord-010027-r0tl01kq	1322	6	quality	quality	NN
cord-010027-r0tl01kq	1322	7	of	of	IN
cord-010027-r0tl01kq	1322	8	genomic	genomic	JJ
cord-010027-r0tl01kq	1322	9	material	material	NN
cord-010027-r0tl01kq	1322	10	between	between	IN
cord-010027-r0tl01kq	1322	11	centres	centre	NNS
cord-010027-r0tl01kq	1322	12	confirming	confirm	VBG
cord-010027-r0tl01kq	1322	13	that	that	IN
cord-010027-r0tl01kq	1322	14	differences	difference	NNS
cord-010027-r0tl01kq	1322	15	in	in	IN
cord-010027-r0tl01kq	1322	16	specimen	specimen	JJ
cord-010027-r0tl01kq	1322	17	handling	handling	NN
cord-010027-r0tl01kq	1322	18	affect	affect	NN
cord-010027-r0tl01kq	1322	19	DNA	dna	NN
cord-010027-r0tl01kq	1322	20	quality	quality	NN
cord-010027-r0tl01kq	1322	21	.	.	.
cord-010027-r0tl01kq	1323	1	Prospective	prospective	JJ
cord-010027-r0tl01kq	1323	2	trials	trial	NNS
cord-010027-r0tl01kq	1323	3	must	must	MD
cord-010027-r0tl01kq	1323	4	address	address	VB
cord-010027-r0tl01kq	1323	5	this	this	DT
cord-010027-r0tl01kq	1323	6	by	by	IN
cord-010027-r0tl01kq	1323	7	standardising	standardise	VBG
cord-010027-r0tl01kq	1323	8	fixation	fixation	NN
cord-010027-r0tl01kq	1323	9	and	and	CC
cord-010027-r0tl01kq	1323	10	processing	processing	NN
cord-010027-r0tl01kq	1323	11	protocols	protocol	NNS
cord-010027-r0tl01kq	1323	12	.	.	.
cord-010027-r0tl01kq	1324	1	The	the	DT
cord-010027-r0tl01kq	1324	2	plane	plane	NN
cord-010027-r0tl01kq	1324	3	of	of	IN
cord-010027-r0tl01kq	1324	4	colon	colon	NN
cord-010027-r0tl01kq	1324	5	cancer	cancer	NN
cord-010027-r0tl01kq	1324	6	resection	resection	NN
cord-010027-r0tl01kq	1324	7	has	have	VBZ
cord-010027-r0tl01kq	1324	8	recently	recently	RB
cord-010027-r0tl01kq	1324	9	been	be	VBN
cord-010027-r0tl01kq	1324	10	shown	show	VBN
cord-010027-r0tl01kq	1324	11	to	to	TO
cord-010027-r0tl01kq	1324	12	predict	predict	VB
cord-010027-r0tl01kq	1324	13	survival	survival	NN
cord-010027-r0tl01kq	1324	14	.	.	.
cord-010027-r0tl01kq	1325	1	Complete	complete	JJ
cord-010027-r0tl01kq	1325	2	mesocolic	mesocolic	NN
cord-010027-r0tl01kq	1325	3	excision	excision	NN
cord-010027-r0tl01kq	1325	4	(	(	-LRB-
cord-010027-r0tl01kq	1325	5	CME	CME	NNP
cord-010027-r0tl01kq	1325	6	)	)	-RRB-
cord-010027-r0tl01kq	1325	7	with	with	IN
cord-010027-r0tl01kq	1325	8	central	central	JJ
cord-010027-r0tl01kq	1325	9	vascular	vascular	JJ
cord-010027-r0tl01kq	1325	10	ligation	ligation	NN
cord-010027-r0tl01kq	1325	11	(	(	-LRB-
cord-010027-r0tl01kq	1325	12	CVL	CVL	NNP
cord-010027-r0tl01kq	1325	13	)	)	-RRB-
cord-010027-r0tl01kq	1325	14	produces	produce	VBZ
cord-010027-r0tl01kq	1325	15	an	an	DT
cord-010027-r0tl01kq	1325	16	oncologically	oncologically	RB
cord-010027-r0tl01kq	1325	17	superior	superior	JJ
cord-010027-r0tl01kq	1325	18	specimen	specimen	NN
cord-010027-r0tl01kq	1325	19	and	and	CC
cord-010027-r0tl01kq	1325	20	appears	appear	VBZ
cord-010027-r0tl01kq	1325	21	to	to	TO
cord-010027-r0tl01kq	1325	22	be	be	VB
cord-010027-r0tl01kq	1325	23	related	relate	VBN
cord-010027-r0tl01kq	1325	24	to	to	IN
cord-010027-r0tl01kq	1325	25	optimal	optimal	JJ
cord-010027-r0tl01kq	1325	26	outcomes	outcome	NNS
cord-010027-r0tl01kq	1325	27	.	.	.
cord-010027-r0tl01kq	1326	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1326	2	aimed	aim	VBD
cord-010027-r0tl01kq	1326	3	to	to	TO
cord-010027-r0tl01kq	1326	4	assess	assess	VB
cord-010027-r0tl01kq	1326	5	whether	whether	IN
cord-010027-r0tl01kq	1326	6	a	a	DT
cord-010027-r0tl01kq	1326	7	regional	regional	JJ
cord-010027-r0tl01kq	1326	8	educational	educational	JJ
cord-010027-r0tl01kq	1326	9	programme	programme	NN
cord-010027-r0tl01kq	1326	10	in	in	IN
cord-010027-r0tl01kq	1326	11	CME	CME	NNP
cord-010027-r0tl01kq	1326	12	with	with	IN
cord-010027-r0tl01kq	1326	13	CVL	CVL	NNP
cord-010027-r0tl01kq	1326	14	led	lead	VBD
cord-010027-r0tl01kq	1326	15	to	to	IN
cord-010027-r0tl01kq	1326	16	an	an	DT
cord-010027-r0tl01kq	1326	17	improvement	improvement	NN
cord-010027-r0tl01kq	1326	18	in	in	IN
cord-010027-r0tl01kq	1326	19	the	the	DT
cord-010027-r0tl01kq	1326	20	quality	quality	NN
cord-010027-r0tl01kq	1326	21	of	of	IN
cord-010027-r0tl01kq	1326	22	colon	colon	NN
cord-010027-r0tl01kq	1326	23	cancer	cancer	NN
cord-010027-r0tl01kq	1326	24	specimens	specimen	NNS
cord-010027-r0tl01kq	1326	25	.	.	.
cord-010027-r0tl01kq	1327	1	Following	follow	VBG
cord-010027-r0tl01kq	1327	2	a	a	DT
cord-010027-r0tl01kq	1327	3	regional	regional	JJ
cord-010027-r0tl01kq	1327	4	educational	educational	JJ
cord-010027-r0tl01kq	1327	5	programme	programme	NN
cord-010027-r0tl01kq	1327	6	in	in	IN
cord-010027-r0tl01kq	1327	7	CME	CME	NNP
cord-010027-r0tl01kq	1327	8	with	with	IN
cord-010027-r0tl01kq	1327	9	CVL	CVL	NNP
cord-010027-r0tl01kq	1327	10	in	in	IN
cord-010027-r0tl01kq	1327	11	the	the	DT
cord-010027-r0tl01kq	1327	12	Capital	Capital	NNP
cord-010027-r0tl01kq	1327	13	and	and	CC
cord-010027-r0tl01kq	1327	14	Zealand	Zealand	NNP
cord-010027-r0tl01kq	1327	15	areas	area	NNS
cord-010027-r0tl01kq	1327	16	of	of	IN
cord-010027-r0tl01kq	1327	17	Denmark	Denmark	NNP
cord-010027-r0tl01kq	1327	18	,	,	,
cord-010027-r0tl01kq	1327	19	686	686	CD
cord-010027-r0tl01kq	1327	20	cases	case	NNS
cord-010027-r0tl01kq	1327	21	of	of	IN
cord-010027-r0tl01kq	1327	22	primary	primary	JJ
cord-010027-r0tl01kq	1327	23	colon	colon	NN
cord-010027-r0tl01kq	1327	24	cancer	cancer	NN
cord-010027-r0tl01kq	1327	25	resected	resect	VBD
cord-010027-r0tl01kq	1327	26	across	across	IN
cord-010027-r0tl01kq	1327	27	six	six	CD
cord-010027-r0tl01kq	1327	28	hospitals	hospital	NNS
cord-010027-r0tl01kq	1327	29	were	be	VBD
cord-010027-r0tl01kq	1327	30	assessed	assess	VBN
cord-010027-r0tl01kq	1327	31	by	by	IN
cord-010027-r0tl01kq	1327	32	grading	grade	VBG
cord-010027-r0tl01kq	1327	33	the	the	DT
cord-010027-r0tl01kq	1327	34	plane	plane	NN
cord-010027-r0tl01kq	1327	35	of	of	IN
cord-010027-r0tl01kq	1327	36	surgery	surgery	NN
cord-010027-r0tl01kq	1327	37	and	and	CC
cord-010027-r0tl01kq	1327	38	undertaking	undertaking	NN
cord-010027-r0tl01kq	1327	39	tissue	tissue	NN
cord-010027-r0tl01kq	1327	40	morphometry	morphometry	NN
cord-010027-r0tl01kq	1327	41	.	.	.
cord-010027-r0tl01kq	1328	1	These	these	DT
cord-010027-r0tl01kq	1328	2	were	be	VBD
cord-010027-r0tl01kq	1328	3	compared	compare	VBN
cord-010027-r0tl01kq	1328	4	to	to	IN
cord-010027-r0tl01kq	1328	5	263	263	CD
cord-010027-r0tl01kq	1328	6	specimens	specimen	NNS
cord-010027-r0tl01kq	1328	7	resected	resect	VBN
cord-010027-r0tl01kq	1328	8	prior	prior	RB
cord-010027-r0tl01kq	1328	9	to	to	IN
cord-010027-r0tl01kq	1328	10	the	the	DT
cord-010027-r0tl01kq	1328	11	educational	educational	JJ
cord-010027-r0tl01kq	1328	12	programme	programme	NN
cord-010027-r0tl01kq	1328	13	.	.	.
cord-010027-r0tl01kq	1329	1	This	this	DT
cord-010027-r0tl01kq	1329	2	work	work	NN
cord-010027-r0tl01kq	1329	3	was	be	VBD
cord-010027-r0tl01kq	1329	4	partly	partly	RB
cord-010027-r0tl01kq	1329	5	supported	support	VBN
cord-010027-r0tl01kq	1329	6	by	by	IN
cord-010027-r0tl01kq	1329	7	a	a	DT
cord-010027-r0tl01kq	1329	8	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	1329	9	undergraduate	undergraduate	NN
cord-010027-r0tl01kq	1329	10	bursary	bursary	NN
cord-010027-r0tl01kq	1329	11	.	.	.
cord-010027-r0tl01kq	1330	1	Across	across	IN
cord-010027-r0tl01kq	1330	2	the	the	DT
cord-010027-r0tl01kq	1330	3	region	region	NN
cord-010027-r0tl01kq	1330	4	,	,	,
cord-010027-r0tl01kq	1330	5	the	the	DT
cord-010027-r0tl01kq	1330	6	mesocolic	mesocolic	NN
cord-010027-r0tl01kq	1330	7	plane	plane	NN
cord-010027-r0tl01kq	1330	8	resection	resection	NN
cord-010027-r0tl01kq	1330	9	rate	rate	NN
cord-010027-r0tl01kq	1330	10	improved	improve	VBN
cord-010027-r0tl01kq	1330	11	from	from	IN
cord-010027-r0tl01kq	1330	12	58	58	CD
cord-010027-r0tl01kq	1330	13	%	%	NN
cord-010027-r0tl01kq	1330	14	to	to	IN
cord-010027-r0tl01kq	1330	15	77	77	CD
cord-010027-r0tl01kq	1330	16	%	%	NN
cord-010027-r0tl01kq	1330	17	(	(	-LRB-
cord-010027-r0tl01kq	1330	18	p<0.0001	p<0.0001	NNP
cord-010027-r0tl01kq	1330	19	)	)	-RRB-
cord-010027-r0tl01kq	1330	20	.	.	.
cord-010027-r0tl01kq	1331	1	Hillerød	Hillerød	NNP
cord-010027-r0tl01kq	1331	2	hospital	hospital	NN
cord-010027-r0tl01kq	1331	3	had	have	VBD
cord-010027-r0tl01kq	1331	4	implemented	implement	VBN
cord-010027-r0tl01kq	1331	5	CME	CME	NNP
cord-010027-r0tl01kq	1331	6	with	with	IN
cord-010027-r0tl01kq	1331	7	CVL	CVL	NNP
cord-010027-r0tl01kq	1331	8	as	as	IN
cord-010027-r0tl01kq	1331	9	standard	standard	NN
cord-010027-r0tl01kq	1331	10	prior	prior	RB
cord-010027-r0tl01kq	1331	11	to	to	IN
cord-010027-r0tl01kq	1331	12	the	the	DT
cord-010027-r0tl01kq	1331	13	educational	educational	JJ
cord-010027-r0tl01kq	1331	14	programme	programme	NN
cord-010027-r0tl01kq	1331	15	and	and	CC
cord-010027-r0tl01kq	1331	16	continued	continue	VBD
cord-010027-r0tl01kq	1331	17	to	to	TO
cord-010027-r0tl01kq	1331	18	produce	produce	VB
cord-010027-r0tl01kq	1331	19	optimal	optimal	JJ
cord-010027-r0tl01kq	1331	20	specimens	specimen	NNS
cord-010027-r0tl01kq	1331	21	.	.	.
cord-010027-r0tl01kq	1332	1	Three	three	CD
cord-010027-r0tl01kq	1332	2	of	of	IN
cord-010027-r0tl01kq	1332	3	the	the	DT
cord-010027-r0tl01kq	1332	4	other	other	JJ
cord-010027-r0tl01kq	1332	5	hospitals	hospital	NNS
cord-010027-r0tl01kq	1332	6	showed	show	VBD
cord-010027-r0tl01kq	1332	7	a	a	DT
cord-010027-r0tl01kq	1332	8	significant	significant	JJ
cord-010027-r0tl01kq	1332	9	improvement	improvement	NN
cord-010027-r0tl01kq	1332	10	in	in	IN
cord-010027-r0tl01kq	1332	11	the	the	DT
cord-010027-r0tl01kq	1332	12	plane	plane	NN
cord-010027-r0tl01kq	1332	13	of	of	IN
cord-010027-r0tl01kq	1332	14	surgical	surgical	JJ
cord-010027-r0tl01kq	1332	15	resection	resection	NN
cord-010027-r0tl01kq	1332	16	.	.	.
cord-010027-r0tl01kq	1333	1	Hillerød	Hillerød	NNP
cord-010027-r0tl01kq	1333	2	specimens	specimen	NNS
cord-010027-r0tl01kq	1333	3	continued	continue	VBD
cord-010027-r0tl01kq	1333	4	to	to	TO
cord-010027-r0tl01kq	1333	5	be	be	VB
cord-010027-r0tl01kq	1333	6	more	more	RBR
cord-010027-r0tl01kq	1333	7	radical	radical	JJ
cord-010027-r0tl01kq	1333	8	with	with	IN
cord-010027-r0tl01kq	1333	9	a	a	DT
cord-010027-r0tl01kq	1333	10	greater	great	JJR
cord-010027-r0tl01kq	1333	11	distance	distance	NN
cord-010027-r0tl01kq	1333	12	between	between	IN
cord-010027-r0tl01kq	1333	13	the	the	DT
cord-010027-r0tl01kq	1333	14	tumour	tumour	NN
cord-010027-r0tl01kq	1333	15	and	and	CC
cord-010027-r0tl01kq	1333	16	the	the	DT
cord-010027-r0tl01kq	1333	17	high	high	JJ
cord-010027-r0tl01kq	1333	18	tie	tie	NN
cord-010027-r0tl01kq	1333	19	,	,	,
cord-010027-r0tl01kq	1333	20	area	area	NN
cord-010027-r0tl01kq	1333	21	of	of	IN
cord-010027-r0tl01kq	1333	22	mesentery	mesentery	NN
cord-010027-r0tl01kq	1333	23	and	and	CC
cord-010027-r0tl01kq	1333	24	lymph	lymph	NN
cord-010027-r0tl01kq	1333	25	node	node	NN
cord-010027-r0tl01kq	1333	26	yield	yield	NN
cord-010027-r0tl01kq	1333	27	compared	compare	VBN
cord-010027-r0tl01kq	1333	28	to	to	IN
cord-010027-r0tl01kq	1333	29	the	the	DT
cord-010027-r0tl01kq	1333	30	other	other	JJ
cord-010027-r0tl01kq	1333	31	five	five	CD
cord-010027-r0tl01kq	1333	32	hospitals	hospital	NNS
cord-010027-r0tl01kq	1333	33	.	.	.
cord-010027-r0tl01kq	1334	1	A	a	DT
cord-010027-r0tl01kq	1334	2	multidisciplinary	multidisciplinary	JJ
cord-010027-r0tl01kq	1334	3	regional	regional	JJ
cord-010027-r0tl01kq	1334	4	educational	educational	JJ
cord-010027-r0tl01kq	1334	5	programme	programme	NN
cord-010027-r0tl01kq	1334	6	in	in	IN
cord-010027-r0tl01kq	1334	7	CME	CME	NNP
cord-010027-r0tl01kq	1334	8	with	with	IN
cord-010027-r0tl01kq	1334	9	CVL	CVL	NNP
cord-010027-r0tl01kq	1334	10	has	have	VBZ
cord-010027-r0tl01kq	1334	11	improved	improve	VBN
cord-010027-r0tl01kq	1334	12	the	the	DT
cord-010027-r0tl01kq	1334	13	oncological	oncological	JJ
cord-010027-r0tl01kq	1334	14	quality	quality	NN
cord-010027-r0tl01kq	1334	15	of	of	IN
cord-010027-r0tl01kq	1334	16	colon	colon	NN
cord-010027-r0tl01kq	1334	17	cancer	cancer	NN
cord-010027-r0tl01kq	1334	18	specimens	specimen	NNS
cord-010027-r0tl01kq	1334	19	as	as	IN
cord-010027-r0tl01kq	1334	20	assessed	assess	VBN
cord-010027-r0tl01kq	1334	21	by	by	IN
cord-010027-r0tl01kq	1334	22	mesocolic	mesocolic	NNP
cord-010027-r0tl01kq	1334	23	planes	plane	NNS
cord-010027-r0tl01kq	1334	24	,	,	,
cord-010027-r0tl01kq	1334	25	however	however	RB
cord-010027-r0tl01kq	1334	26	,	,	,
cord-010027-r0tl01kq	1334	27	there	there	EX
cord-010027-r0tl01kq	1334	28	has	have	VBZ
cord-010027-r0tl01kq	1334	29	been	be	VBN
cord-010027-r0tl01kq	1334	30	no	no	DT
cord-010027-r0tl01kq	1334	31	significant	significant	JJ
cord-010027-r0tl01kq	1334	32	effect	effect	NN
cord-010027-r0tl01kq	1334	33	on	on	IN
cord-010027-r0tl01kq	1334	34	the	the	DT
cord-010027-r0tl01kq	1334	35	amount	amount	NN
cord-010027-r0tl01kq	1334	36	of	of	IN
cord-010027-r0tl01kq	1334	37	tissue	tissue	NN
cord-010027-r0tl01kq	1334	38	resected	resect	VBN
cord-010027-r0tl01kq	1334	39	.	.	.
cord-010027-r0tl01kq	1335	1	Surgeons	surgeon	NNS
cord-010027-r0tl01kq	1335	2	at	at	IN
cord-010027-r0tl01kq	1335	3	Hillerød	Hillerød	NNP
cord-010027-r0tl01kq	1335	4	continue	continue	VBP
cord-010027-r0tl01kq	1335	5	to	to	TO
cord-010027-r0tl01kq	1335	6	produce	produce	VB
cord-010027-r0tl01kq	1335	7	more	more	JJR
cord-010027-r0tl01kq	1335	8	radical	radical	JJ
cord-010027-r0tl01kq	1335	9	specimens	specimen	NNS
cord-010027-r0tl01kq	1335	10	suggesting	suggest	VBG
cord-010027-r0tl01kq	1335	11	that	that	IN
cord-010027-r0tl01kq	1335	12	such	such	JJ
cord-010027-r0tl01kq	1335	13	educational	educational	JJ
cord-010027-r0tl01kq	1335	14	programmes	programme	NNS
cord-010027-r0tl01kq	1335	15	are	be	VBP
cord-010027-r0tl01kq	1335	16	not	not	RB
cord-010027-r0tl01kq	1335	17	alone	alone	JJ
cord-010027-r0tl01kq	1335	18	sufficient	sufficient	JJ
cord-010027-r0tl01kq	1335	19	to	to	TO
cord-010027-r0tl01kq	1335	20	increase	increase	VB
cord-010027-r0tl01kq	1335	21	the	the	DT
cord-010027-r0tl01kq	1335	22	amount	amount	NN
cord-010027-r0tl01kq	1335	23	of	of	IN
cord-010027-r0tl01kq	1335	24	tissue	tissue	NN
cord-010027-r0tl01kq	1335	25	resected	resect	VBN
cord-010027-r0tl01kq	1335	26	around	around	IN
cord-010027-r0tl01kq	1335	27	the	the	DT
cord-010027-r0tl01kq	1335	28	tumour	tumour	NN
cord-010027-r0tl01kq	1335	29	.	.	.
cord-010027-r0tl01kq	1336	1	Hillerød	Hillerød	NNP
cord-010027-r0tl01kq	1336	2	have	have	VBP
cord-010027-r0tl01kq	1336	3	recently	recently	RB
cord-010027-r0tl01kq	1336	4	published	publish	VBN
cord-010027-r0tl01kq	1336	5	their	-PRON-	PRP$
cord-010027-r0tl01kq	1336	6	long	long	JJ
cord-010027-r0tl01kq	1336	7	term	term	NN
cord-010027-r0tl01kq	1336	8	outcomes	outcome	NNS
cord-010027-r0tl01kq	1336	9	with	with	IN
cord-010027-r0tl01kq	1336	10	survivals	survival	NNS
cord-010027-r0tl01kq	1336	11	being	be	VBG
cord-010027-r0tl01kq	1336	12	10	10	CD
cord-010027-r0tl01kq	1336	13	%	%	NN
cord-010027-r0tl01kq	1336	14	higher	high	JJR
cord-010027-r0tl01kq	1336	15	when	when	WRB
cord-010027-r0tl01kq	1336	16	compared	compare	VBN
cord-010027-r0tl01kq	1336	17	to	to	IN
cord-010027-r0tl01kq	1336	18	other	other	JJ
cord-010027-r0tl01kq	1336	19	hospitals	hospital	NNS
cord-010027-r0tl01kq	1336	20	across	across	IN
cord-010027-r0tl01kq	1336	21	the	the	DT
cord-010027-r0tl01kq	1336	22	region	region	NN
cord-010027-r0tl01kq	1336	23	.	.	.
cord-010027-r0tl01kq	1337	1	Further	further	JJ
cord-010027-r0tl01kq	1337	2	engagement	engagement	NN
cord-010027-r0tl01kq	1337	3	is	be	VBZ
cord-010027-r0tl01kq	1337	4	now	now	RB
cord-010027-r0tl01kq	1337	5	necessary	necessary	JJ
cord-010027-r0tl01kq	1337	6	to	to	TO
cord-010027-r0tl01kq	1337	7	ensure	ensure	VB
cord-010027-r0tl01kq	1337	8	that	that	IN
cord-010027-r0tl01kq	1337	9	optimal	optimal	JJ
cord-010027-r0tl01kq	1337	10	outcomes	outcome	NNS
cord-010027-r0tl01kq	1337	11	are	be	VBP
cord-010027-r0tl01kq	1337	12	achieved	achieve	VBN
cord-010027-r0tl01kq	1337	13	across	across	IN
cord-010027-r0tl01kq	1337	14	the	the	DT
cord-010027-r0tl01kq	1337	15	region	region	NN
cord-010027-r0tl01kq	1337	16	.	.	.
cord-010027-r0tl01kq	1338	1	Investigating	investigate	VBG
cord-010027-r0tl01kq	1338	2	the	the	DT
cord-010027-r0tl01kq	1338	3	Faecal	Faecal	NNP
cord-010027-r0tl01kq	1338	4	Microbiome	Microbiome	NNP
cord-010027-r0tl01kq	1338	5	in	in	IN
cord-010027-r0tl01kq	1338	6	Formalin	Formalin	NNP
cord-010027-r0tl01kq	1338	7	Fixed	fix	VBN
cord-010027-r0tl01kq	1338	8	Paraffin	paraffin	NN
cord-010027-r0tl01kq	1338	9	Embedded	embed	VBN
cord-010027-r0tl01kq	1338	10	(	(	-LRB-
cord-010027-r0tl01kq	1338	11	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1338	12	)	)	-RRB-
cord-010027-r0tl01kq	1338	13	Material	material	NN
cord-010027-r0tl01kq	1338	14	P	p	NN
cord-010027-r0tl01kq	1338	15	ITR	ITR	NNP
cord-010027-r0tl01kq	1338	16	Jobling	Jobling	NNP
cord-010027-r0tl01kq	1338	17	1	1	CD
cord-010027-r0tl01kq	1338	18	;	;	:
cord-010027-r0tl01kq	1338	19	M	M	NNP
cord-010027-r0tl01kq	1338	20	Taylor	Taylor	NNP
cord-010027-r0tl01kq	1338	21	2	2	CD
cord-010027-r0tl01kq	1338	22	;	;	:
cord-010027-r0tl01kq	1338	23	C	C	NNP
cord-010027-r0tl01kq	1338	24	Young	Young	NNP
cord-010027-r0tl01kq	1338	25	2	2	CD
cord-010027-r0tl01kq	1338	26	;	;	:
cord-010027-r0tl01kq	1338	27	HM	HM	NNP
cord-010027-r0tl01kq	1338	28	Wood	Wood	NNP
cord-010027-r0tl01kq	1338	29	2	2	CD
cord-010027-r0tl01kq	1338	30	;	;	:
cord-010027-r0tl01kq	1338	31	P	p	NN
cord-010027-r0tl01kq	1338	32	Quirke	Quirke	NNP
cord-010027-r0tl01kq	1338	33	2	2	CD
cord-010027-r0tl01kq	1338	34	1	1	CD
cord-010027-r0tl01kq	1338	35	University	University	NNP
cord-010027-r0tl01kq	1338	36	of	of	IN
cord-010027-r0tl01kq	1338	37	Leeds	Leeds	NNP
cord-010027-r0tl01kq	1338	38	,	,	,
cord-010027-r0tl01kq	1338	39	Leeds	Leeds	NNP
cord-010027-r0tl01kq	1338	40	,	,	,
cord-010027-r0tl01kq	1338	41	UK	UK	NNP
cord-010027-r0tl01kq	1338	42	;	;	:
cord-010027-r0tl01kq	1338	43	2	2	CD
cord-010027-r0tl01kq	1338	44	Leeds	Leeds	NNP
cord-010027-r0tl01kq	1338	45	Institute	Institute	NNP
cord-010027-r0tl01kq	1338	46	of	of	IN
cord-010027-r0tl01kq	1338	47	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1338	48	and	and	CC
cord-010027-r0tl01kq	1338	49	Pathology	Pathology	NNP
cord-010027-r0tl01kq	1338	50	,	,	,
cord-010027-r0tl01kq	1338	51	Leeds	Leeds	NNP
cord-010027-r0tl01kq	1338	52	,	,	,
cord-010027-r0tl01kq	1338	53	UK	UK	NNP
cord-010027-r0tl01kq	1338	54	Purpose	Purpose	NNP
cord-010027-r0tl01kq	1338	55	:	:	:
cord-010027-r0tl01kq	1338	56	Research	research	NN
cord-010027-r0tl01kq	1338	57	into	into	IN
cord-010027-r0tl01kq	1338	58	the	the	DT
cord-010027-r0tl01kq	1338	59	faecal	faecal	JJ
cord-010027-r0tl01kq	1338	60	microbiome	microbiome	NN
cord-010027-r0tl01kq	1338	61	has	have	VBZ
cord-010027-r0tl01kq	1338	62	shown	show	VBN
cord-010027-r0tl01kq	1338	63	a	a	DT
cord-010027-r0tl01kq	1338	64	diverse	diverse	JJ
cord-010027-r0tl01kq	1338	65	population	population	NN
cord-010027-r0tl01kq	1338	66	with	with	IN
cord-010027-r0tl01kq	1338	67	a	a	DT
cord-010027-r0tl01kq	1338	68	high	high	JJ
cord-010027-r0tl01kq	1338	69	level	level	NN
cord-010027-r0tl01kq	1338	70	of	of	IN
cord-010027-r0tl01kq	1338	71	variability	variability	NN
cord-010027-r0tl01kq	1338	72	between	between	IN
cord-010027-r0tl01kq	1338	73	individuals	individual	NNS
cord-010027-r0tl01kq	1338	74	.	.	.
cord-010027-r0tl01kq	1339	1	Altered	altered	JJ
cord-010027-r0tl01kq	1339	2	faecal	faecal	JJ
cord-010027-r0tl01kq	1339	3	microbiomes	microbiome	NNS
cord-010027-r0tl01kq	1339	4	are	be	VBP
cord-010027-r0tl01kq	1339	5	present	present	JJ
cord-010027-r0tl01kq	1339	6	in	in	IN
cord-010027-r0tl01kq	1339	7	a	a	DT
cord-010027-r0tl01kq	1339	8	range	range	NN
cord-010027-r0tl01kq	1339	9	of	of	IN
cord-010027-r0tl01kq	1339	10	diseases	disease	NNS
cord-010027-r0tl01kq	1339	11	but	but	CC
cord-010027-r0tl01kq	1339	12	work	work	NN
cord-010027-r0tl01kq	1339	13	remains	remain	VBZ
cord-010027-r0tl01kq	1339	14	to	to	TO
cord-010027-r0tl01kq	1339	15	understand	understand	VB
cord-010027-r0tl01kq	1339	16	their	-PRON-	PRP$
cord-010027-r0tl01kq	1339	17	role	role	NN
cord-010027-r0tl01kq	1339	18	in	in	IN
cord-010027-r0tl01kq	1339	19	gastrointestinal	gastrointestinal	JJ
cord-010027-r0tl01kq	1339	20	disease	disease	NN
cord-010027-r0tl01kq	1339	21	.	.	.
cord-010027-r0tl01kq	1340	1	Current	current	JJ
cord-010027-r0tl01kq	1340	2	research	research	NN
cord-010027-r0tl01kq	1340	3	into	into	IN
cord-010027-r0tl01kq	1340	4	the	the	DT
cord-010027-r0tl01kq	1340	5	microbiome	microbiome	NN
cord-010027-r0tl01kq	1340	6	makes	make	VBZ
cord-010027-r0tl01kq	1340	7	use	use	NN
cord-010027-r0tl01kq	1340	8	of	of	IN
cord-010027-r0tl01kq	1340	9	fresh	fresh	JJ
cord-010027-r0tl01kq	1340	10	or	or	CC
cord-010027-r0tl01kq	1340	11	frozen	frozen	JJ
cord-010027-r0tl01kq	1340	12	faecal	faecal	JJ
cord-010027-r0tl01kq	1340	13	samples	sample	NNS
cord-010027-r0tl01kq	1340	14	.	.	.
cord-010027-r0tl01kq	1341	1	This	this	DT
cord-010027-r0tl01kq	1341	2	restricts	restrict	VBZ
cord-010027-r0tl01kq	1341	3	researchers	researcher	NNS
cord-010027-r0tl01kq	1341	4	to	to	IN
cord-010027-r0tl01kq	1341	5	predominantly	predominantly	RB
cord-010027-r0tl01kq	1341	6	prospective	prospective	JJ
cord-010027-r0tl01kq	1341	7	study	study	NN
cord-010027-r0tl01kq	1341	8	designs	design	NNS
cord-010027-r0tl01kq	1341	9	.	.	.
cord-010027-r0tl01kq	1342	1	One	one	CD
cord-010027-r0tl01kq	1342	2	potential	potential	JJ
cord-010027-r0tl01kq	1342	3	method	method	NN
cord-010027-r0tl01kq	1342	4	for	for	IN
cord-010027-r0tl01kq	1342	5	rapidly	rapidly	RB
cord-010027-r0tl01kq	1342	6	increasing	increase	VBG
cord-010027-r0tl01kq	1342	7	and	and	CC
cord-010027-r0tl01kq	1342	8	diversifying	diversify	VBG
cord-010027-r0tl01kq	1342	9	research	research	NN
cord-010027-r0tl01kq	1342	10	is	be	VBZ
cord-010027-r0tl01kq	1342	11	the	the	DT
cord-010027-r0tl01kq	1342	12	retrospective	retrospective	JJ
cord-010027-r0tl01kq	1342	13	study	study	NN
cord-010027-r0tl01kq	1342	14	of	of	IN
cord-010027-r0tl01kq	1342	15	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1342	16	material	material	NN
cord-010027-r0tl01kq	1342	17	.	.	.
cord-010027-r0tl01kq	1343	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1343	2	aimed	aim	VBD
cord-010027-r0tl01kq	1343	3	to	to	TO
cord-010027-r0tl01kq	1343	4	investigate	investigate	VB
cord-010027-r0tl01kq	1343	5	the	the	DT
cord-010027-r0tl01kq	1343	6	feasibility	feasibility	NN
cord-010027-r0tl01kq	1343	7	of	of	IN
cord-010027-r0tl01kq	1343	8	typing	type	VBG
cord-010027-r0tl01kq	1343	9	the	the	DT
cord-010027-r0tl01kq	1343	10	microbiome	microbiome	NN
cord-010027-r0tl01kq	1343	11	in	in	IN
cord-010027-r0tl01kq	1343	12	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1343	13	faecal	faecal	JJ
cord-010027-r0tl01kq	1343	14	samples	sample	NNS
cord-010027-r0tl01kq	1343	15	using	use	VBG
cord-010027-r0tl01kq	1343	16	next	next	JJ
cord-010027-r0tl01kq	1343	17	generation	generation	NN
cord-010027-r0tl01kq	1343	18	sequencing	sequencing	NN
cord-010027-r0tl01kq	1343	19	(	(	-LRB-
cord-010027-r0tl01kq	1343	20	NGS	NGS	NNP
cord-010027-r0tl01kq	1343	21	)	)	-RRB-
cord-010027-r0tl01kq	1343	22	technology	technology	NN
cord-010027-r0tl01kq	1343	23	.	.	.
cord-010027-r0tl01kq	1344	1	Methods	method	NNS
cord-010027-r0tl01kq	1344	2	:	:	:
cord-010027-r0tl01kq	1345	1	Material	material	NN
cord-010027-r0tl01kq	1345	2	from	from	IN
cord-010027-r0tl01kq	1345	3	six	six	CD
cord-010027-r0tl01kq	1345	4	faecal	faecal	JJ
cord-010027-r0tl01kq	1345	5	samples	sample	NNS
cord-010027-r0tl01kq	1345	6	was	be	VBD
cord-010027-r0tl01kq	1345	7	divided	divide	VBN
cord-010027-r0tl01kq	1345	8	and	and	CC
cord-010027-r0tl01kq	1345	9	stored	store	VBN
cord-010027-r0tl01kq	1345	10	as	as	IN
cord-010027-r0tl01kq	1345	11	frozen	frozen	JJ
cord-010027-r0tl01kq	1345	12	or	or	CC
cord-010027-r0tl01kq	1345	13	fixed	fix	VBN
cord-010027-r0tl01kq	1345	14	and	and	CC
cord-010027-r0tl01kq	1345	15	paraffin	paraffin	NN
cord-010027-r0tl01kq	1345	16	embedded	embed	VBN
cord-010027-r0tl01kq	1345	17	creating	create	VBG
cord-010027-r0tl01kq	1345	18	two	two	CD
cord-010027-r0tl01kq	1345	19	matched	match	VBN
cord-010027-r0tl01kq	1345	20	sub	sub	NN
cord-010027-r0tl01kq	1345	21	-	-	NNS
cord-010027-r0tl01kq	1345	22	groups	group	NNS
cord-010027-r0tl01kq	1345	23	.	.	.
cord-010027-r0tl01kq	1346	1	To	to	TO
cord-010027-r0tl01kq	1346	2	assess	assess	VB
cord-010027-r0tl01kq	1346	3	assay	assay	NN
cord-010027-r0tl01kq	1346	4	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	1346	5	one	one	CD
cord-010027-r0tl01kq	1346	6	sample	sample	NN
cord-010027-r0tl01kq	1346	7	was	be	VBD
cord-010027-r0tl01kq	1346	8	diluted	dilute	VBN
cord-010027-r0tl01kq	1346	9	to	to	IN
cord-010027-r0tl01kq	1346	10	eight	eight	CD
cord-010027-r0tl01kq	1346	11	different	different	JJ
cord-010027-r0tl01kq	1346	12	concentrations	concentration	NNS
cord-010027-r0tl01kq	1346	13	before	before	IN
cord-010027-r0tl01kq	1346	14	fixing	fix	VBG
cord-010027-r0tl01kq	1346	15	and	and	CC
cord-010027-r0tl01kq	1346	16	embedding	embedding	NN
cord-010027-r0tl01kq	1346	17	.	.	.
cord-010027-r0tl01kq	1347	1	The	the	DT
cord-010027-r0tl01kq	1347	2	V4	V4	NNP
cord-010027-r0tl01kq	1347	3	and	and	CC
cord-010027-r0tl01kq	1347	4	V6	v6	NN
cord-010027-r0tl01kq	1347	5	regions	region	NNS
cord-010027-r0tl01kq	1347	6	of	of	IN
cord-010027-r0tl01kq	1347	7	the	the	DT
cord-010027-r0tl01kq	1347	8	16s	16s	NNPS
cord-010027-r0tl01kq	1347	9	rRNA	rrna	NN
cord-010027-r0tl01kq	1347	10	gene	gene	NN
cord-010027-r0tl01kq	1347	11	were	be	VBD
cord-010027-r0tl01kq	1347	12	amplified	amplify	VBN
cord-010027-r0tl01kq	1347	13	.	.	.
cord-010027-r0tl01kq	1348	1	Primer	primer	NN
cord-010027-r0tl01kq	1348	2	pairs	pair	NNS
cord-010027-r0tl01kq	1348	3	created	create	VBD
cord-010027-r0tl01kq	1348	4	approximately	approximately	RB
cord-010027-r0tl01kq	1348	5	240bp	240bp	NNP
cord-010027-r0tl01kq	1348	6	and	and	CC
cord-010027-r0tl01kq	1348	7	98bp	98bp	JJ
cord-010027-r0tl01kq	1348	8	targets	target	NNS
cord-010027-r0tl01kq	1348	9	in	in	IN
cord-010027-r0tl01kq	1348	10	E.coli	e.coli	NN
cord-010027-r0tl01kq	1348	11	respectively	respectively	RB
cord-010027-r0tl01kq	1348	12	.	.	.
cord-010027-r0tl01kq	1349	1	PCR	PCR	NNP
cord-010027-r0tl01kq	1349	2	products	product	NNS
cord-010027-r0tl01kq	1349	3	were	be	VBD
cord-010027-r0tl01kq	1349	4	multiplexed	multiplexe	VBN
cord-010027-r0tl01kq	1349	5	and	and	CC
cord-010027-r0tl01kq	1349	6	sequenced	sequence	VBN
cord-010027-r0tl01kq	1349	7	on	on	IN
cord-010027-r0tl01kq	1349	8	an	an	DT
cord-010027-r0tl01kq	1349	9	Illumina	Illumina	NNP
cord-010027-r0tl01kq	1349	10	MiSeq	MiSeq	NNP
cord-010027-r0tl01kq	1349	11	.	.	.
cord-010027-r0tl01kq	1350	1	QIIME	QIIME	NNP
cord-010027-r0tl01kq	1350	2	software	software	NN
cord-010027-r0tl01kq	1350	3	was	be	VBD
cord-010027-r0tl01kq	1350	4	used	use	VBN
cord-010027-r0tl01kq	1350	5	for	for	IN
cord-010027-r0tl01kq	1350	6	analysis	analysis	NN
cord-010027-r0tl01kq	1350	7	.	.	.
cord-010027-r0tl01kq	1351	1	Results	result	NNS
cord-010027-r0tl01kq	1351	2	:	:	:
cord-010027-r0tl01kq	1351	3	Analysis	analysis	NN
cord-010027-r0tl01kq	1351	4	of	of	IN
cord-010027-r0tl01kq	1351	5	alpha	alpha	NN
cord-010027-r0tl01kq	1352	1	(	(	-LRB-
cord-010027-r0tl01kq	1352	2	within	within	IN
cord-010027-r0tl01kq	1352	3	sample	sample	NN
cord-010027-r0tl01kq	1352	4	)	)	-RRB-
cord-010027-r0tl01kq	1352	5	diversity	diversity	NN
cord-010027-r0tl01kq	1352	6	showed	show	VBD
cord-010027-r0tl01kq	1352	7	a	a	DT
cord-010027-r0tl01kq	1352	8	significant	significant	JJ
cord-010027-r0tl01kq	1352	9	difference	difference	NN
cord-010027-r0tl01kq	1352	10	between	between	IN
cord-010027-r0tl01kq	1352	11	sub	sub	NN
cord-010027-r0tl01kq	1352	12	-	-	NNS
cord-010027-r0tl01kq	1352	13	groups	group	NNS
cord-010027-r0tl01kq	1352	14	when	when	WRB
cord-010027-r0tl01kq	1352	15	targeting	target	VBG
cord-010027-r0tl01kq	1352	16	V4	v4	NN
cord-010027-r0tl01kq	1352	17	(	(	-LRB-
cord-010027-r0tl01kq	1352	18	p=0.05	p=0.05	NNP
cord-010027-r0tl01kq	1352	19	)	)	-RRB-
cord-010027-r0tl01kq	1352	20	but	but	CC
cord-010027-r0tl01kq	1352	21	not	not	RB
cord-010027-r0tl01kq	1352	22	V6	V6	NNP
cord-010027-r0tl01kq	1352	23	.	.	.
cord-010027-r0tl01kq	1353	1	Analysis	analysis	NN
cord-010027-r0tl01kq	1353	2	of	of	IN
cord-010027-r0tl01kq	1353	3	beta	beta	NN
cord-010027-r0tl01kq	1353	4	(	(	-LRB-
cord-010027-r0tl01kq	1353	5	between	between	IN
cord-010027-r0tl01kq	1353	6	sample	sample	NN
cord-010027-r0tl01kq	1353	7	)	)	-RRB-
cord-010027-r0tl01kq	1353	8	diversity	diversity	NN
cord-010027-r0tl01kq	1353	9	showed	show	VBD
cord-010027-r0tl01kq	1353	10	a	a	DT
cord-010027-r0tl01kq	1353	11	significant	significant	JJ
cord-010027-r0tl01kq	1353	12	difference	difference	NN
cord-010027-r0tl01kq	1353	13	between	between	IN
cord-010027-r0tl01kq	1353	14	sub	sub	NN
cord-010027-r0tl01kq	1353	15	-	-	NNS
cord-010027-r0tl01kq	1353	16	groups	group	NNS
cord-010027-r0tl01kq	1353	17	when	when	WRB
cord-010027-r0tl01kq	1353	18	targeting	target	VBG
cord-010027-r0tl01kq	1353	19	V4	v4	NN
cord-010027-r0tl01kq	1353	20	(	(	-LRB-
cord-010027-r0tl01kq	1353	21	p=0.01	p=0.01	NNP
cord-010027-r0tl01kq	1353	22	)	)	-RRB-
cord-010027-r0tl01kq	1353	23	while	while	IN
cord-010027-r0tl01kq	1353	24	the	the	DT
cord-010027-r0tl01kq	1353	25	V6	V6	NNP
cord-010027-r0tl01kq	1353	26	region	region	NN
cord-010027-r0tl01kq	1353	27	showed	show	VBD
cord-010027-r0tl01kq	1353	28	a	a	DT
cord-010027-r0tl01kq	1353	29	reduced	reduce	VBN
cord-010027-r0tl01kq	1353	30	,	,	,
cord-010027-r0tl01kq	1353	31	but	but	CC
cord-010027-r0tl01kq	1353	32	still	still	RB
cord-010027-r0tl01kq	1353	33	significant	significant	JJ
cord-010027-r0tl01kq	1353	34	(	(	-LRB-
cord-010027-r0tl01kq	1353	35	p=0.02	p=0.02	NN
cord-010027-r0tl01kq	1353	36	)	)	-RRB-
cord-010027-r0tl01kq	1353	37	difference	difference	NN
cord-010027-r0tl01kq	1353	38	.	.	.
cord-010027-r0tl01kq	1354	1	The	the	DT
cord-010027-r0tl01kq	1354	2	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	1354	3	assay	assay	NN
cord-010027-r0tl01kq	1354	4	showed	show	VBD
cord-010027-r0tl01kq	1354	5	comparable	comparable	JJ
cord-010027-r0tl01kq	1354	6	results	result	NNS
cord-010027-r0tl01kq	1354	7	down	down	RB
cord-010027-r0tl01kq	1354	8	to	to	IN
cord-010027-r0tl01kq	1354	9	0.5	0.5	CD
cord-010027-r0tl01kq	1354	10	%	%	NN
cord-010027-r0tl01kq	1354	11	concentration	concentration	NN
cord-010027-r0tl01kq	1354	12	levels	level	NNS
cord-010027-r0tl01kq	1354	13	.	.	.
cord-010027-r0tl01kq	1355	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1355	2	:	:	:
cord-010027-r0tl01kq	1356	1	To	to	IN
cord-010027-r0tl01kq	1356	2	our	-PRON-	PRP$
cord-010027-r0tl01kq	1356	3	knowledge	knowledge	NN
cord-010027-r0tl01kq	1356	4	this	this	DT
cord-010027-r0tl01kq	1356	5	is	be	VBZ
cord-010027-r0tl01kq	1356	6	the	the	DT
cord-010027-r0tl01kq	1356	7	first	first	JJ
cord-010027-r0tl01kq	1356	8	feasibility	feasibility	NN
cord-010027-r0tl01kq	1356	9	study	study	NN
cord-010027-r0tl01kq	1356	10	generating	generate	VBG
cord-010027-r0tl01kq	1356	11	NGS	NGS	NNP
cord-010027-r0tl01kq	1356	12	data	datum	NNS
cord-010027-r0tl01kq	1356	13	on	on	IN
cord-010027-r0tl01kq	1356	14	the	the	DT
cord-010027-r0tl01kq	1356	15	microbiome	microbiome	NN
cord-010027-r0tl01kq	1356	16	from	from	IN
cord-010027-r0tl01kq	1356	17	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1356	18	faecal	faecal	JJ
cord-010027-r0tl01kq	1356	19	material	material	NN
cord-010027-r0tl01kq	1356	20	.	.	.
cord-010027-r0tl01kq	1357	1	Variation	variation	NN
cord-010027-r0tl01kq	1357	2	between	between	IN
cord-010027-r0tl01kq	1357	3	matched	match	VBN
cord-010027-r0tl01kq	1357	4	frozen	frozen	JJ
cord-010027-r0tl01kq	1357	5	and	and	CC
cord-010027-r0tl01kq	1357	6	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1357	7	faecal	faecal	JJ
cord-010027-r0tl01kq	1357	8	material	material	NN
cord-010027-r0tl01kq	1357	9	was	be	VBD
cord-010027-r0tl01kq	1357	10	less	less	JJR
cord-010027-r0tl01kq	1357	11	when	when	WRB
cord-010027-r0tl01kq	1357	12	targeting	target	VBG
cord-010027-r0tl01kq	1357	13	V6	v6	NN
cord-010027-r0tl01kq	1357	14	compared	compare	VBN
cord-010027-r0tl01kq	1357	15	to	to	IN
cord-010027-r0tl01kq	1357	16	V4	V4	NNP
cord-010027-r0tl01kq	1357	17	.	.	.
cord-010027-r0tl01kq	1358	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1358	2	hypothesise	hypothesise	VBP
cord-010027-r0tl01kq	1358	3	this	this	DT
cord-010027-r0tl01kq	1358	4	may	may	MD
cord-010027-r0tl01kq	1358	5	be	be	VB
cord-010027-r0tl01kq	1358	6	due	due	JJ
cord-010027-r0tl01kq	1358	7	to	to	IN
cord-010027-r0tl01kq	1358	8	the	the	DT
cord-010027-r0tl01kq	1358	9	shorter	short	JJR
cord-010027-r0tl01kq	1358	10	amplicon	amplicon	NN
cord-010027-r0tl01kq	1358	11	undergoing	undergo	VBG
cord-010027-r0tl01kq	1358	12	less	less	JJR
cord-010027-r0tl01kq	1358	13	DNA	dna	NN
cord-010027-r0tl01kq	1358	14	fragmentation	fragmentation	NN
cord-010027-r0tl01kq	1358	15	in	in	IN
cord-010027-r0tl01kq	1358	16	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1358	17	material	material	NN
cord-010027-r0tl01kq	1358	18	.	.	.
cord-010027-r0tl01kq	1359	1	There	there	EX
cord-010027-r0tl01kq	1359	2	are	be	VBP
cord-010027-r0tl01kq	1359	3	several	several	JJ
cord-010027-r0tl01kq	1359	4	platforms	platform	NNS
cord-010027-r0tl01kq	1359	5	available	available	JJ
cord-010027-r0tl01kq	1359	6	for	for	IN
cord-010027-r0tl01kq	1359	7	DNA	dna	NN
cord-010027-r0tl01kq	1359	8	mutation	mutation	NN
cord-010027-r0tl01kq	1359	9	detection	detection	NN
cord-010027-r0tl01kq	1359	10	in	in	IN
cord-010027-r0tl01kq	1359	11	formalin	formalin	NN
cord-010027-r0tl01kq	1359	12	-	-	HYPH
cord-010027-r0tl01kq	1359	13	fixed	fix	VBN
cord-010027-r0tl01kq	1359	14	paraffin	paraffin	NN
cord-010027-r0tl01kq	1359	15	-	-	HYPH
cord-010027-r0tl01kq	1359	16	embedded	embed	VBN
cord-010027-r0tl01kq	1359	17	(	(	-LRB-
cord-010027-r0tl01kq	1359	18	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1359	19	)	)	-RRB-
cord-010027-r0tl01kq	1359	20	material	material	NN
cord-010027-r0tl01kq	1359	21	,	,	,
cord-010027-r0tl01kq	1359	22	all	all	DT
cord-010027-r0tl01kq	1359	23	with	with	IN
cord-010027-r0tl01kq	1359	24	their	-PRON-	PRP$
cord-010027-r0tl01kq	1359	25	relative	relative	JJ
cord-010027-r0tl01kq	1359	26	strengths	strength	NNS
cord-010027-r0tl01kq	1359	27	and	and	CC
cord-010027-r0tl01kq	1359	28	weaknesses	weakness	NNS
cord-010027-r0tl01kq	1359	29	.	.	.
cord-010027-r0tl01kq	1360	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1360	2	investigated	investigate	VBD
cord-010027-r0tl01kq	1360	3	the	the	DT
cord-010027-r0tl01kq	1360	4	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1360	5	®	®	POS
cord-010027-r0tl01kq	1360	6	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1360	7	Assay	Assay	NNP
cord-010027-r0tl01kq	1360	8	Kit	kit	NN
cord-010027-r0tl01kq	1360	9	(	(	-LRB-
cord-010027-r0tl01kq	1360	10	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1360	11	)	)	-RRB-
cord-010027-r0tl01kq	1360	12	in	in	IN
cord-010027-r0tl01kq	1360	13	comparison	comparison	NN
cord-010027-r0tl01kq	1360	14	to	to	IN
cord-010027-r0tl01kq	1360	15	pyrosequencing	pyrosequence	VBG
cord-010027-r0tl01kq	1360	16	in	in	IN
cord-010027-r0tl01kq	1360	17	patients	patient	NNS
cord-010027-r0tl01kq	1360	18	with	with	IN
cord-010027-r0tl01kq	1360	19	operable	operable	JJ
cord-010027-r0tl01kq	1360	20	colon	colon	NN
cord-010027-r0tl01kq	1360	21	cancer	cancer	NN
cord-010027-r0tl01kq	1360	22	recruited	recruit	VBN
cord-010027-r0tl01kq	1360	23	to	to	IN
cord-010027-r0tl01kq	1360	24	the	the	DT
cord-010027-r0tl01kq	1360	25	phase	phase	NN
cord-010027-r0tl01kq	1360	26	II	ii	CD
cord-010027-r0tl01kq	1360	27	component	component	NN
cord-010027-r0tl01kq	1360	28	of	of	IN
cord-010027-r0tl01kq	1360	29	the	the	DT
cord-010027-r0tl01kq	1360	30	NCRI	NCRI	NNP
cord-010027-r0tl01kq	1360	31	FOxTROT	FOxTROT	NNP
cord-010027-r0tl01kq	1360	32	trial	trial	NN
cord-010027-r0tl01kq	1360	33	of	of	IN
cord-010027-r0tl01kq	1360	34	pre	pre	JJ
cord-010027-r0tl01kq	1360	35	-	-	JJ
cord-010027-r0tl01kq	1360	36	operative	operative	JJ
cord-010027-r0tl01kq	1360	37	vs.	vs.	FW
cord-010027-r0tl01kq	1360	38	post	post	JJ
cord-010027-r0tl01kq	1360	39	-	-	JJ
cord-010027-r0tl01kq	1360	40	operative	operative	JJ
cord-010027-r0tl01kq	1360	41	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	1360	42	.	.	.
cord-010027-r0tl01kq	1361	1	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1361	2	samples	sample	NNS
cord-010027-r0tl01kq	1361	3	of	of	IN
cord-010027-r0tl01kq	1361	4	tumour	tumour	NN
cord-010027-r0tl01kq	1361	5	from	from	IN
cord-010027-r0tl01kq	1361	6	the	the	DT
cord-010027-r0tl01kq	1361	7	resection	resection	NN
cord-010027-r0tl01kq	1361	8	specimens	specimen	NNS
cord-010027-r0tl01kq	1361	9	of	of	IN
cord-010027-r0tl01kq	1361	10	132	132	CD
cord-010027-r0tl01kq	1361	11	cases	case	NNS
cord-010027-r0tl01kq	1361	12	were	be	VBD
cord-010027-r0tl01kq	1361	13	tested	test	VBN
cord-010027-r0tl01kq	1361	14	for	for	IN
cord-010027-r0tl01kq	1361	15	KRAS	kra	NNS
cord-010027-r0tl01kq	1361	16	12/13/61	12/13/61	CD
cord-010027-r0tl01kq	1361	17	and	and	CC
cord-010027-r0tl01kq	1362	1	BRAF	BRAF	NNP
cord-010027-r0tl01kq	1362	2	V600E	V600E	NNP
cord-010027-r0tl01kq	1362	3	mutations	mutation	NNS
cord-010027-r0tl01kq	1362	4	using	use	VBG
cord-010027-r0tl01kq	1362	5	pyrosequencing	pyrosequence	VBG
cord-010027-r0tl01kq	1362	6	.	.	.
cord-010027-r0tl01kq	1363	1	The	the	DT
cord-010027-r0tl01kq	1363	2	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1363	3	assay	assay	NN
cord-010027-r0tl01kq	1363	4	allows	allow	VBZ
cord-010027-r0tl01kq	1363	5	for	for	IN
cord-010027-r0tl01kq	1363	6	the	the	DT
cord-010027-r0tl01kq	1363	7	interrogation	interrogation	NN
cord-010027-r0tl01kq	1363	8	of	of	IN
cord-010027-r0tl01kq	1363	9	74	74	CD
cord-010027-r0tl01kq	1363	10	mutations	mutation	NNS
cord-010027-r0tl01kq	1363	11	across	across	IN
cord-010027-r0tl01kq	1363	12	nine	nine	CD
cord-010027-r0tl01kq	1363	13	genes	gene	NNS
cord-010027-r0tl01kq	1363	14	.	.	.
cord-010027-r0tl01kq	1364	1	Pre	pre	JJ
cord-010027-r0tl01kq	1364	2	-	-	JJ
cord-010027-r0tl01kq	1364	3	extracted	extract	VBN
cord-010027-r0tl01kq	1364	4	DNA	DNA	NNP
cord-010027-r0tl01kq	1364	5	was	be	VBD
cord-010027-r0tl01kq	1364	6	analysed	analyse	VBN
cord-010027-r0tl01kq	1364	7	on	on	IN
cord-010027-r0tl01kq	1364	8	the	the	DT
cord-010027-r0tl01kq	1364	9	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1364	10	assay	assay	NN
cord-010027-r0tl01kq	1364	11	and	and	CC
cord-010027-r0tl01kq	1364	12	quality	quality	NN
cord-010027-r0tl01kq	1364	13	control	control	NN
cord-010027-r0tl01kq	1364	14	(	(	-LRB-
cord-010027-r0tl01kq	1364	15	QC	QC	NNP
cord-010027-r0tl01kq	1364	16	)	)	-RRB-
cord-010027-r0tl01kq	1364	17	scores	score	NNS
cord-010027-r0tl01kq	1364	18	generated	generate	VBN
cord-010027-r0tl01kq	1364	19	,	,	,
cord-010027-r0tl01kq	1364	20	indicating	indicate	VBG
cord-010027-r0tl01kq	1364	21	confidence	confidence	NN
cord-010027-r0tl01kq	1364	22	in	in	IN
cord-010027-r0tl01kq	1364	23	mutation	mutation	NN
cord-010027-r0tl01kq	1364	24	calling	call	VBG
cord-010027-r0tl01kq	1364	25	results	result	NNS
cord-010027-r0tl01kq	1364	26	.	.	.
cord-010027-r0tl01kq	1365	1	The	the	DT
cord-010027-r0tl01kq	1365	2	mutational	mutational	JJ
cord-010027-r0tl01kq	1365	3	status	status	NN
cord-010027-r0tl01kq	1365	4	of	of	IN
cord-010027-r0tl01kq	1365	5	all	all	DT
cord-010027-r0tl01kq	1365	6	samples	sample	NNS
cord-010027-r0tl01kq	1365	7	was	be	VBD
cord-010027-r0tl01kq	1365	8	automatically	automatically	RB
cord-010027-r0tl01kq	1365	9	assessed	assess	VBN
cord-010027-r0tl01kq	1365	10	in	in	IN
cord-010027-r0tl01kq	1365	11	the	the	DT
cord-010027-r0tl01kq	1365	12	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	1365	13	SM	SM	NNP
cord-010027-r0tl01kq	1365	14	Viewer	Viewer	NNP
cord-010027-r0tl01kq	1365	15	,	,	,
cord-010027-r0tl01kq	1365	16	and	and	CC
cord-010027-r0tl01kq	1365	17	then	then	RB
cord-010027-r0tl01kq	1365	18	manually	manually	RB
cord-010027-r0tl01kq	1365	19	confirmed	confirm	VBD
cord-010027-r0tl01kq	1365	20	.	.	.
cord-010027-r0tl01kq	1366	1	This	this	DT
cord-010027-r0tl01kq	1366	2	work	work	NN
cord-010027-r0tl01kq	1366	3	is	be	VBZ
cord-010027-r0tl01kq	1366	4	presented	present	VBN
cord-010027-r0tl01kq	1366	5	on	on	IN
cord-010027-r0tl01kq	1366	6	behalf	behalf	NN
cord-010027-r0tl01kq	1366	7	of	of	IN
cord-010027-r0tl01kq	1366	8	the	the	DT
cord-010027-r0tl01kq	1366	9	FOxTROT	FOxTROT	NNP
cord-010027-r0tl01kq	1366	10	Collaborative	Collaborative	NNP
cord-010027-r0tl01kq	1366	11	and	and	CC
cord-010027-r0tl01kq	1366	12	was	be	VBD
cord-010027-r0tl01kq	1366	13	part	part	NN
cord-010027-r0tl01kq	1366	14	funded	fund	VBN
cord-010027-r0tl01kq	1366	15	by	by	IN
cord-010027-r0tl01kq	1366	16	a	a	DT
cord-010027-r0tl01kq	1366	17	PathSoc	PathSoc	NNP
cord-010027-r0tl01kq	1366	18	fellowship	fellowship	NN
cord-010027-r0tl01kq	1366	19	.	.	.
cord-010027-r0tl01kq	1367	1	Out	out	IN
cord-010027-r0tl01kq	1367	2	of	of	IN
cord-010027-r0tl01kq	1367	3	132	132	CD
cord-010027-r0tl01kq	1367	4	samples	sample	NNS
cord-010027-r0tl01kq	1367	5	,	,	,
cord-010027-r0tl01kq	1367	6	22	22	CD
cord-010027-r0tl01kq	1367	7	failed	fail	VBD
cord-010027-r0tl01kq	1367	8	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1367	9	QC	QC	NNP
cord-010027-r0tl01kq	1367	10	thresholds	threshold	NNS
cord-010027-r0tl01kq	1367	11	,	,	,
cord-010027-r0tl01kq	1367	12	however	however	RB
cord-010027-r0tl01kq	1367	13	,	,	,
cord-010027-r0tl01kq	1367	14	only	only	RB
cord-010027-r0tl01kq	1367	15	10	10	CD
cord-010027-r0tl01kq	1367	16	of	of	IN
cord-010027-r0tl01kq	1367	17	these	these	DT
cord-010027-r0tl01kq	1367	18	were	be	VBD
cord-010027-r0tl01kq	1367	19	deemed	deem	VBN
cord-010027-r0tl01kq	1367	20	inconclusive	inconclusive	JJ
cord-010027-r0tl01kq	1367	21	by	by	IN
cord-010027-r0tl01kq	1367	22	manual	manual	JJ
cord-010027-r0tl01kq	1367	23	interrogation	interrogation	NN
cord-010027-r0tl01kq	1367	24	.	.	.
cord-010027-r0tl01kq	1368	1	130	130	CD
cord-010027-r0tl01kq	1368	2	samples	sample	NNS
cord-010027-r0tl01kq	1368	3	were	be	VBD
cord-010027-r0tl01kq	1368	4	interpretable	interpretable	JJ
cord-010027-r0tl01kq	1368	5	by	by	IN
cord-010027-r0tl01kq	1368	6	pyrosequencing	pyrosequence	VBG
cord-010027-r0tl01kq	1368	7	.	.	.
cord-010027-r0tl01kq	1369	1	Of	of	IN
cord-010027-r0tl01kq	1369	2	the	the	DT
cord-010027-r0tl01kq	1369	3	120	120	CD
cord-010027-r0tl01kq	1369	4	samples	sample	NNS
cord-010027-r0tl01kq	1369	5	that	that	WDT
cord-010027-r0tl01kq	1369	6	produced	produce	VBD
cord-010027-r0tl01kq	1369	7	conclusive	conclusive	JJ
cord-010027-r0tl01kq	1369	8	results	result	NNS
cord-010027-r0tl01kq	1369	9	on	on	IN
cord-010027-r0tl01kq	1369	10	both	both	DT
cord-010027-r0tl01kq	1369	11	platforms	platform	NNS
cord-010027-r0tl01kq	1369	12	,	,	,
cord-010027-r0tl01kq	1369	13	the	the	DT
cord-010027-r0tl01kq	1369	14	concordance	concordance	NN
cord-010027-r0tl01kq	1369	15	rate	rate	NN
cord-010027-r0tl01kq	1369	16	was	be	VBD
cord-010027-r0tl01kq	1369	17	very	very	RB
cord-010027-r0tl01kq	1369	18	high	high	JJ
cord-010027-r0tl01kq	1369	19	at	at	IN
cord-010027-r0tl01kq	1369	20	95.8	95.8	CD
cord-010027-r0tl01kq	1369	21	%	%	NN
cord-010027-r0tl01kq	1369	22	when	when	WRB
cord-010027-r0tl01kq	1369	23	calling	call	VBG
cord-010027-r0tl01kq	1369	24	a	a	DT
cord-010027-r0tl01kq	1369	25	mutated	mutate	VBN
cord-010027-r0tl01kq	1369	26	versus	versus	IN
cord-010027-r0tl01kq	1369	27	non	non	JJ
cord-010027-r0tl01kq	1369	28	-	-	JJ
cord-010027-r0tl01kq	1369	29	mutated	mutated	JJ
cord-010027-r0tl01kq	1369	30	KRAS	KRAS	NNP
cord-010027-r0tl01kq	1369	31	/	/	SYM
cord-010027-r0tl01kq	1369	32	BRAF	BRAF	NNP
cord-010027-r0tl01kq	1369	33	status	status	NN
cord-010027-r0tl01kq	1369	34	.	.	.
cord-010027-r0tl01kq	1370	1	Mutations	mutation	NNS
cord-010027-r0tl01kq	1370	2	were	be	VBD
cord-010027-r0tl01kq	1370	3	'	'	``
cord-010027-r0tl01kq	1370	4	missed	miss	VBN
cord-010027-r0tl01kq	1370	5	'	'	''
cord-010027-r0tl01kq	1370	6	by	by	IN
cord-010027-r0tl01kq	1370	7	pyrosequencing	pyrosequence	VBG
cord-010027-r0tl01kq	1370	8	in	in	IN
cord-010027-r0tl01kq	1370	9	only	only	RB
cord-010027-r0tl01kq	1370	10	1	1	CD
cord-010027-r0tl01kq	1370	11	case	case	NN
cord-010027-r0tl01kq	1370	12	(	(	-LRB-
cord-010027-r0tl01kq	1370	13	0.8	0.8	CD
cord-010027-r0tl01kq	1370	14	%	%	NN
cord-010027-r0tl01kq	1370	15	)	)	-RRB-
cord-010027-r0tl01kq	1370	16	and	and	CC
cord-010027-r0tl01kq	1370	17	by	by	IN
cord-010027-r0tl01kq	1370	18	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1370	19	in	in	IN
cord-010027-r0tl01kq	1370	20	4	4	CD
cord-010027-r0tl01kq	1370	21	cases	case	NNS
cord-010027-r0tl01kq	1370	22	(	(	-LRB-
cord-010027-r0tl01kq	1370	23	3.4	3.4	CD
cord-010027-r0tl01kq	1370	24	%	%	NN
cord-010027-r0tl01kq	1370	25	)	)	-RRB-
cord-010027-r0tl01kq	1370	26	.	.	.
cord-010027-r0tl01kq	1371	1	In	in	IN
cord-010027-r0tl01kq	1371	2	addition	addition	NN
cord-010027-r0tl01kq	1371	3	,	,	,
cord-010027-r0tl01kq	1371	4	the	the	DT
cord-010027-r0tl01kq	1371	5	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1371	6	assay	assay	NN
cord-010027-r0tl01kq	1371	7	provides	provide	VBZ
cord-010027-r0tl01kq	1371	8	mutational	mutational	JJ
cord-010027-r0tl01kq	1371	9	data	datum	NNS
cord-010027-r0tl01kq	1371	10	in	in	IN
cord-010027-r0tl01kq	1371	11	additional	additional	JJ
cord-010027-r0tl01kq	1371	12	genes	gene	NNS
cord-010027-r0tl01kq	1371	13	along	along	IN
cord-010027-r0tl01kq	1371	14	with	with	IN
cord-010027-r0tl01kq	1371	15	copy	copy	NN
cord-010027-r0tl01kq	1371	16	number	number	NN
cord-010027-r0tl01kq	1371	17	(	(	-LRB-
cord-010027-r0tl01kq	1371	18	CN	CN	NNP
cord-010027-r0tl01kq	1371	19	)	)	-RRB-
cord-010027-r0tl01kq	1371	20	and	and	CC
cord-010027-r0tl01kq	1371	21	loss	loss	NN
cord-010027-r0tl01kq	1371	22	of	of	IN
cord-010027-r0tl01kq	1371	23	heterozygosity	heterozygosity	NN
cord-010027-r0tl01kq	1371	24	(	(	-LRB-
cord-010027-r0tl01kq	1371	25	LOH	LOH	NNP
cord-010027-r0tl01kq	1371	26	)	)	-RRB-
cord-010027-r0tl01kq	1371	27	information	information	NN
cord-010027-r0tl01kq	1371	28	.	.	.
cord-010027-r0tl01kq	1372	1	In	in	IN
cord-010027-r0tl01kq	1372	2	patients	patient	NNS
cord-010027-r0tl01kq	1372	3	with	with	IN
cord-010027-r0tl01kq	1372	4	colon	colon	NN
cord-010027-r0tl01kq	1372	5	cancer	cancer	NN
cord-010027-r0tl01kq	1372	6	recruited	recruit	VBN
cord-010027-r0tl01kq	1372	7	to	to	IN
cord-010027-r0tl01kq	1372	8	the	the	DT
cord-010027-r0tl01kq	1372	9	NCRI	NCRI	NNP
cord-010027-r0tl01kq	1372	10	FOxTROT	FOxTROT	NNP
cord-010027-r0tl01kq	1372	11	trial	trial	NN
cord-010027-r0tl01kq	1372	12	,	,	,
cord-010027-r0tl01kq	1372	13	the	the	DT
cord-010027-r0tl01kq	1372	14	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1372	15	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1372	16	assay	assay	NN
cord-010027-r0tl01kq	1372	17	shows	show	VBZ
cord-010027-r0tl01kq	1372	18	good	good	JJ
cord-010027-r0tl01kq	1372	19	correlation	correlation	NN
cord-010027-r0tl01kq	1372	20	with	with	IN
cord-010027-r0tl01kq	1372	21	pyrosequencing	pyrosequencing	NN
cord-010027-r0tl01kq	1372	22	when	when	WRB
cord-010027-r0tl01kq	1372	23	determining	determine	VBG
cord-010027-r0tl01kq	1372	24	the	the	DT
cord-010027-r0tl01kq	1372	25	mutational	mutational	JJ
cord-010027-r0tl01kq	1372	26	status	status	NN
cord-010027-r0tl01kq	1372	27	of	of	IN
cord-010027-r0tl01kq	1372	28	KRAS	KRAS	NNP
cord-010027-r0tl01kq	1372	29	/	/	SYM
cord-010027-r0tl01kq	1372	30	BRAF	BRAF	NNP
cord-010027-r0tl01kq	1372	31	.	.	.
cord-010027-r0tl01kq	1373	1	Although	although	IN
cord-010027-r0tl01kq	1373	2	pyrosequencing	pyrosequencing	NN
cord-010027-r0tl01kq	1373	3	has	have	VBZ
cord-010027-r0tl01kq	1373	4	a	a	DT
cord-010027-r0tl01kq	1373	5	slightly	slightly	RB
cord-010027-r0tl01kq	1373	6	lower	low	JJR
cord-010027-r0tl01kq	1373	7	failure	failure	NN
cord-010027-r0tl01kq	1373	8	rate	rate	NN
cord-010027-r0tl01kq	1373	9	,	,	,
cord-010027-r0tl01kq	1373	10	the	the	DT
cord-010027-r0tl01kq	1373	11	OncoScan	OncoScan	NNP
cord-010027-r0tl01kq	1373	12	has	have	VBZ
cord-010027-r0tl01kq	1373	13	the	the	DT
cord-010027-r0tl01kq	1373	14	added	add	VBN
cord-010027-r0tl01kq	1373	15	advantage	advantage	NN
cord-010027-r0tl01kq	1373	16	of	of	IN
cord-010027-r0tl01kq	1373	17	targeting	target	VBG
cord-010027-r0tl01kq	1373	18	more	more	JJR
cord-010027-r0tl01kq	1373	19	mutations	mutation	NNS
cord-010027-r0tl01kq	1373	20	,	,	,
cord-010027-r0tl01kq	1373	21	producing	produce	VBG
cord-010027-r0tl01kq	1373	22	genome	genome	NN
cord-010027-r0tl01kq	1373	23	wide	wide	JJ
cord-010027-r0tl01kq	1373	24	CN	cn	NN
cord-010027-r0tl01kq	1373	25	,	,	,
cord-010027-r0tl01kq	1373	26	and	and	CC
cord-010027-r0tl01kq	1373	27	LOH	LOH	NNP
cord-010027-r0tl01kq	1373	28	information	information	NN
cord-010027-r0tl01kq	1373	29	in	in	IN
cord-010027-r0tl01kq	1373	30	one	one	CD
cord-010027-r0tl01kq	1373	31	assay	assay	NN
cord-010027-r0tl01kq	1373	32	.	.	.
cord-010027-r0tl01kq	1374	1	Excellent	excellent	JJ
cord-010027-r0tl01kq	1374	2	anatomical	anatomical	JJ
cord-010027-r0tl01kq	1374	3	knowledge	knowledge	NN
cord-010027-r0tl01kq	1374	4	of	of	IN
cord-010027-r0tl01kq	1374	5	the	the	DT
cord-010027-r0tl01kq	1374	6	rectum	rectum	NN
cord-010027-r0tl01kq	1374	7	and	and	CC
cord-010027-r0tl01kq	1374	8	surrounding	surround	VBG
cord-010027-r0tl01kq	1374	9	structures	structure	NNS
cord-010027-r0tl01kq	1374	10	is	be	VBZ
cord-010027-r0tl01kq	1374	11	essential	essential	JJ
cord-010027-r0tl01kq	1374	12	for	for	IN
cord-010027-r0tl01kq	1374	13	total	total	JJ
cord-010027-r0tl01kq	1374	14	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1374	15	excision	excision	NN
cord-010027-r0tl01kq	1374	16	(	(	-LRB-
cord-010027-r0tl01kq	1374	17	TME	TME	NNP
cord-010027-r0tl01kq	1374	18	)	)	-RRB-
cord-010027-r0tl01kq	1374	19	.	.	.
cord-010027-r0tl01kq	1375	1	Denonvilliers	Denonvilliers	NNP
cord-010027-r0tl01kq	1375	2	'	'	POS
cord-010027-r0tl01kq	1375	3	fascia	fascia	NN
cord-010027-r0tl01kq	1375	4	(	(	-LRB-
cord-010027-r0tl01kq	1375	5	DVF	DVF	NNP
cord-010027-r0tl01kq	1375	6	)	)	-RRB-
cord-010027-r0tl01kq	1375	7	has	have	VBZ
cord-010027-r0tl01kq	1375	8	been	be	VBN
cord-010027-r0tl01kq	1375	9	frequently	frequently	RB
cord-010027-r0tl01kq	1375	10	studied	study	VBN
cord-010027-r0tl01kq	1375	11	,	,	,
cord-010027-r0tl01kq	1375	12	though	though	IN
cord-010027-r0tl01kq	1375	13	the	the	DT
cord-010027-r0tl01kq	1375	14	optimal	optimal	JJ
cord-010027-r0tl01kq	1375	15	anterior	anterior	JJ
cord-010027-r0tl01kq	1375	16	plane	plane	NN
cord-010027-r0tl01kq	1375	17	in	in	IN
cord-010027-r0tl01kq	1375	18	TME	TME	NNP
cord-010027-r0tl01kq	1375	19	is	be	VBZ
cord-010027-r0tl01kq	1375	20	still	still	RB
cord-010027-r0tl01kq	1375	21	disputed	dispute	VBN
cord-010027-r0tl01kq	1375	22	.	.	.
cord-010027-r0tl01kq	1376	1	The	the	DT
cord-010027-r0tl01kq	1376	2	relationship	relationship	NN
cord-010027-r0tl01kq	1376	3	of	of	IN
cord-010027-r0tl01kq	1376	4	the	the	DT
cord-010027-r0tl01kq	1376	5	lateral	lateral	JJ
cord-010027-r0tl01kq	1376	6	edge	edge	NN
cord-010027-r0tl01kq	1376	7	of	of	IN
cord-010027-r0tl01kq	1376	8	DVF	DVF	NNP
cord-010027-r0tl01kq	1376	9	to	to	IN
cord-010027-r0tl01kq	1376	10	the	the	DT
cord-010027-r0tl01kq	1376	11	autonomic	autonomic	JJ
cord-010027-r0tl01kq	1376	12	nerves	nerve	NNS
cord-010027-r0tl01kq	1376	13	is	be	VBZ
cord-010027-r0tl01kq	1376	14	also	also	RB
cord-010027-r0tl01kq	1376	15	unclear	unclear	JJ
cord-010027-r0tl01kq	1376	16	.	.	.
cord-010027-r0tl01kq	1377	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1377	2	studied	study	VBD
cord-010027-r0tl01kq	1377	3	whole	whole	JJ
cord-010027-r0tl01kq	1377	4	-	-	HYPH
cord-010027-r0tl01kq	1377	5	mount	mount	NN
cord-010027-r0tl01kq	1377	6	microscopic	microscopic	JJ
cord-010027-r0tl01kq	1377	7	sections	section	NNS
cord-010027-r0tl01kq	1377	8	of	of	IN
cord-010027-r0tl01kq	1377	9	en	en	JJ
cord-010027-r0tl01kq	1377	10	-	-	HYPH
cord-010027-r0tl01kq	1377	11	bloc	bloc	NNP
cord-010027-r0tl01kq	1377	12	cadaveric	cadaveric	JJ
cord-010027-r0tl01kq	1377	13	pelvic	pelvic	JJ
cord-010027-r0tl01kq	1377	14	exenteration	exenteration	NN
cord-010027-r0tl01kq	1377	15	specimens	specimen	NNS
cord-010027-r0tl01kq	1377	16	and	and	CC
cord-010027-r0tl01kq	1377	17	describe	describe	VB
cord-010027-r0tl01kq	1377	18	implications	implication	NNS
cord-010027-r0tl01kq	1377	19	for	for	IN
cord-010027-r0tl01kq	1377	20	TME	TME	NNP
cord-010027-r0tl01kq	1377	21	.	.	.
cord-010027-r0tl01kq	1378	1	Four	four	CD
cord-010027-r0tl01kq	1378	2	human	human	JJ
cord-010027-r0tl01kq	1378	3	adult	adult	NN
cord-010027-r0tl01kq	1378	4	cadaveric	cadaveric	JJ
cord-010027-r0tl01kq	1378	5	specimens	specimen	NNS
cord-010027-r0tl01kq	1378	6	(	(	-LRB-
cord-010027-r0tl01kq	1378	7	two	two	CD
cord-010027-r0tl01kq	1378	8	males	male	NNS
cord-010027-r0tl01kq	1378	9	,	,	,
cord-010027-r0tl01kq	1378	10	two	two	CD
cord-010027-r0tl01kq	1378	11	females	female	NNS
cord-010027-r0tl01kq	1378	12	)	)	-RRB-
cord-010027-r0tl01kq	1378	13	were	be	VBD
cord-010027-r0tl01kq	1378	14	obtained	obtain	VBN
cord-010027-r0tl01kq	1378	15	from	from	IN
cord-010027-r0tl01kq	1378	16	the	the	DT
cord-010027-r0tl01kq	1378	17	Leeds	Leeds	NNP
cord-010027-r0tl01kq	1378	18	GIFT	GIFT	NNP
cord-010027-r0tl01kq	1378	19	Research	Research	NNP
cord-010027-r0tl01kq	1378	20	Tissue	Tissue	NNP
cord-010027-r0tl01kq	1378	21	Programme	Programme	NNP
cord-010027-r0tl01kq	1378	22	.	.	.
cord-010027-r0tl01kq	1379	1	Paraffin	paraffin	NN
cord-010027-r0tl01kq	1379	2	-	-	HYPH
cord-010027-r0tl01kq	1379	3	embedded	embed	VBN
cord-010027-r0tl01kq	1379	4	mega	mega	NNS
cord-010027-r0tl01kq	1379	5	-	-	NNS
cord-010027-r0tl01kq	1379	6	blocks	block	NNS
cord-010027-r0tl01kq	1379	7	were	be	VBD
cord-010027-r0tl01kq	1379	8	produced	produce	VBN
cord-010027-r0tl01kq	1379	9	and	and	CC
cord-010027-r0tl01kq	1379	10	serially	serially	RB
cord-010027-r0tl01kq	1379	11	sectioned	section	VBN
cord-010027-r0tl01kq	1379	12	at	at	IN
cord-010027-r0tl01kq	1379	13	50	50	CD
cord-010027-r0tl01kq	1379	14	and	and	CC
cord-010027-r0tl01kq	1379	15	250	250	CD
cord-010027-r0tl01kq	1379	16	µm	µm	CD
cord-010027-r0tl01kq	1379	17	intervals	interval	NNS
cord-010027-r0tl01kq	1379	18	.	.	.
cord-010027-r0tl01kq	1380	1	Sections	section	NNS
cord-010027-r0tl01kq	1380	2	were	be	VBD
cord-010027-r0tl01kq	1380	3	stained	stain	VBN
cord-010027-r0tl01kq	1380	4	with	with	IN
cord-010027-r0tl01kq	1380	5	haematoxylin	haematoxylin	NNP
cord-010027-r0tl01kq	1380	6	&	&	CC
cord-010027-r0tl01kq	1380	7	eosin	eosin	NNP
cord-010027-r0tl01kq	1380	8	,	,	,
cord-010027-r0tl01kq	1380	9	Masson	Masson	NNP
cord-010027-r0tl01kq	1380	10	's	's	POS
cord-010027-r0tl01kq	1380	11	trichrome	trichrome	JJ
cord-010027-r0tl01kq	1380	12	and	and	CC
cord-010027-r0tl01kq	1380	13	Millers	Millers	NNP
cord-010027-r0tl01kq	1380	14	'	'	POS
cord-010027-r0tl01kq	1380	15	elastin	elastin	NN
cord-010027-r0tl01kq	1380	16	.	.	.
cord-010027-r0tl01kq	1381	1	Additionally	additionally	RB
cord-010027-r0tl01kq	1381	2	,	,	,
cord-010027-r0tl01kq	1381	3	a	a	DT
cord-010027-r0tl01kq	1381	4	developmental	developmental	JJ
cord-010027-r0tl01kq	1381	5	series	series	NN
cord-010027-r0tl01kq	1381	6	of	of	IN
cord-010027-r0tl01kq	1381	7	eleven	eleven	CD
cord-010027-r0tl01kq	1381	8	human	human	JJ
cord-010027-r0tl01kq	1381	9	fetal	fetal	JJ
cord-010027-r0tl01kq	1381	10	pelvic	pelvic	JJ
cord-010027-r0tl01kq	1381	11	specimens	specimen	NNS
cord-010027-r0tl01kq	1381	12	(	(	-LRB-
cord-010027-r0tl01kq	1381	13	embryonic	embryonic	JJ
cord-010027-r0tl01kq	1381	14	age	age	NN
cord-010027-r0tl01kq	1381	15	of	of	IN
cord-010027-r0tl01kq	1381	16	9	9	CD
cord-010027-r0tl01kq	1381	17	-	-	SYM
cord-010027-r0tl01kq	1381	18	20	20	CD
cord-010027-r0tl01kq	1381	19	weeks	week	NNS
cord-010027-r0tl01kq	1381	20	)	)	-RRB-
cord-010027-r0tl01kq	1381	21	were	be	VBD
cord-010027-r0tl01kq	1381	22	studied	study	VBN
cord-010027-r0tl01kq	1381	23	.	.	.
cord-010027-r0tl01kq	1382	1	DVF	DVF	NNP
cord-010027-r0tl01kq	1382	2	consisted	consist	VBD
cord-010027-r0tl01kq	1382	3	of	of	IN
cord-010027-r0tl01kq	1382	4	multiple	multiple	JJ
cord-010027-r0tl01kq	1382	5	fascial	fascial	JJ
cord-010027-r0tl01kq	1382	6	condensations	condensation	NNS
cord-010027-r0tl01kq	1382	7	of	of	IN
cord-010027-r0tl01kq	1382	8	collagen	collagen	NN
cord-010027-r0tl01kq	1382	9	and	and	CC
cord-010027-r0tl01kq	1382	10	smooth	smooth	JJ
cord-010027-r0tl01kq	1382	11	muscle	muscle	NN
cord-010027-r0tl01kq	1382	12	fibres	fibre	NNS
cord-010027-r0tl01kq	1382	13	and	and	CC
cord-010027-r0tl01kq	1382	14	was	be	VBD
cord-010027-r0tl01kq	1382	15	indistinguishable	indistinguishable	JJ
cord-010027-r0tl01kq	1382	16	from	from	IN
cord-010027-r0tl01kq	1382	17	the	the	DT
cord-010027-r0tl01kq	1382	18	anterior	anterior	JJ
cord-010027-r0tl01kq	1382	19	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1382	20	fascia	fascia	NN
cord-010027-r0tl01kq	1382	21	and	and	CC
cord-010027-r0tl01kq	1382	22	the	the	DT
cord-010027-r0tl01kq	1382	23	capsule	capsule	NN
cord-010027-r0tl01kq	1382	24	of	of	IN
cord-010027-r0tl01kq	1382	25	the	the	DT
cord-010027-r0tl01kq	1382	26	prostate	prostate	NN
cord-010027-r0tl01kq	1382	27	or	or	CC
cord-010027-r0tl01kq	1382	28	posterior	posterior	JJ
cord-010027-r0tl01kq	1382	29	vaginal	vaginal	JJ
cord-010027-r0tl01kq	1382	30	wall	wall	NN
cord-010027-r0tl01kq	1382	31	.	.	.
cord-010027-r0tl01kq	1383	1	The	the	DT
cord-010027-r0tl01kq	1383	2	lateral	lateral	JJ
cord-010027-r0tl01kq	1383	3	edges	edge	NNS
cord-010027-r0tl01kq	1383	4	of	of	IN
cord-010027-r0tl01kq	1383	5	DVF	DVF	NNP
cord-010027-r0tl01kq	1383	6	appeared	appear	VBD
cord-010027-r0tl01kq	1383	7	fan	fan	NN
cord-010027-r0tl01kq	1383	8	-	-	HYPH
cord-010027-r0tl01kq	1383	9	shaped	shape	VBN
cord-010027-r0tl01kq	1383	10	,	,	,
cord-010027-r0tl01kq	1383	11	and	and	CC
cord-010027-r0tl01kq	1383	12	the	the	DT
cord-010027-r0tl01kq	1383	13	most	most	RBS
cord-010027-r0tl01kq	1383	14	posterior	posterior	JJ
cord-010027-r0tl01kq	1383	15	part	part	NN
cord-010027-r0tl01kq	1383	16	was	be	VBD
cord-010027-r0tl01kq	1383	17	continuous	continuous	JJ
cord-010027-r0tl01kq	1383	18	with	with	IN
cord-010027-r0tl01kq	1383	19	the	the	DT
cord-010027-r0tl01kq	1383	20	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1383	21	fascia	fascia	NN
cord-010027-r0tl01kq	1383	22	.	.	.
cord-010027-r0tl01kq	1384	1	Peri	peri	JJ
cord-010027-r0tl01kq	1384	2	-	-	HYPH
cord-010027-r0tl01kq	1384	3	rectal	rectal	JJ
cord-010027-r0tl01kq	1384	4	fasciae	fascia	NNS
cord-010027-r0tl01kq	1384	5	were	be	VBD
cord-010027-r0tl01kq	1384	6	not	not	RB
cord-010027-r0tl01kq	1384	7	identified	identify	VBN
cord-010027-r0tl01kq	1384	8	in	in	IN
cord-010027-r0tl01kq	1384	9	fetal	fetal	JJ
cord-010027-r0tl01kq	1384	10	specimens	specimen	NNS
cord-010027-r0tl01kq	1384	11	.	.	.
cord-010027-r0tl01kq	1385	1	DVF	DVF	NNP
cord-010027-r0tl01kq	1385	2	is	be	VBZ
cord-010027-r0tl01kq	1385	3	adherent	adherent	JJ
cord-010027-r0tl01kq	1385	4	to	to	IN
cord-010027-r0tl01kq	1385	5	and	and	CC
cord-010027-r0tl01kq	1385	6	continuous	continuous	JJ
cord-010027-r0tl01kq	1385	7	with	with	IN
cord-010027-r0tl01kq	1385	8	the	the	DT
cord-010027-r0tl01kq	1385	9	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1385	10	fascia	fascia	NN
cord-010027-r0tl01kq	1385	11	.	.	.
cord-010027-r0tl01kq	1386	1	Optimal	optimal	JJ
cord-010027-r0tl01kq	1386	2	surgical	surgical	JJ
cord-010027-r0tl01kq	1386	3	dissection	dissection	NN
cord-010027-r0tl01kq	1386	4	during	during	IN
cord-010027-r0tl01kq	1386	5	TME	TME	NNP
cord-010027-r0tl01kq	1386	6	should	should	MD
cord-010027-r0tl01kq	1386	7	be	be	VB
cord-010027-r0tl01kq	1386	8	carried	carry	VBN
cord-010027-r0tl01kq	1386	9	out	out	RP
cord-010027-r0tl01kq	1386	10	anterior	anterior	NN
cord-010027-r0tl01kq	1386	11	to	to	IN
cord-010027-r0tl01kq	1386	12	DVF	DVF	NNP
cord-010027-r0tl01kq	1386	13	to	to	TO
cord-010027-r0tl01kq	1386	14	ensure	ensure	VB
cord-010027-r0tl01kq	1386	15	radical	radical	JJ
cord-010027-r0tl01kq	1386	16	removal	removal	NN
cord-010027-r0tl01kq	1386	17	,	,	,
cord-010027-r0tl01kq	1386	18	particularly	particularly	RB
cord-010027-r0tl01kq	1386	19	for	for	IN
cord-010027-r0tl01kq	1386	20	anterior	anterior	JJ
cord-010027-r0tl01kq	1386	21	tumours	tumour	NNS
cord-010027-r0tl01kq	1386	22	.	.	.
cord-010027-r0tl01kq	1387	1	Autonomic	autonomic	JJ
cord-010027-r0tl01kq	1387	2	nerves	nerve	NNS
cord-010027-r0tl01kq	1387	3	are	be	VBP
cord-010027-r0tl01kq	1387	4	at	at	IN
cord-010027-r0tl01kq	1387	5	risk	risk	NN
cord-010027-r0tl01kq	1387	6	,	,	,
cord-010027-r0tl01kq	1387	7	but	but	CC
cord-010027-r0tl01kq	1387	8	can	can	MD
cord-010027-r0tl01kq	1387	9	be	be	VB
cord-010027-r0tl01kq	1387	10	preserved	preserve	VBN
cord-010027-r0tl01kq	1387	11	by	by	IN
cord-010027-r0tl01kq	1387	12	following	follow	VBG
cord-010027-r0tl01kq	1387	13	the	the	DT
cord-010027-r0tl01kq	1387	14	mesorectal	mesorectal	JJ
cord-010027-r0tl01kq	1387	15	fascia	fascia	NN
cord-010027-r0tl01kq	1387	16	along	along	IN
cord-010027-r0tl01kq	1387	17	the	the	DT
cord-010027-r0tl01kq	1387	18	anterolateral	anterolateral	JJ
cord-010027-r0tl01kq	1387	19	mesorectum	mesorectum	NN
cord-010027-r0tl01kq	1387	20	.	.	.
cord-010027-r0tl01kq	1388	1	The	the	DT
cord-010027-r0tl01kq	1388	2	lack	lack	NN
cord-010027-r0tl01kq	1388	3	of	of	IN
cord-010027-r0tl01kq	1388	4	evident	evident	JJ
cord-010027-r0tl01kq	1388	5	fasciae	fascia	NNS
cord-010027-r0tl01kq	1388	6	in	in	IN
cord-010027-r0tl01kq	1388	7	fetal	fetal	JJ
cord-010027-r0tl01kq	1388	8	specimens	specimen	NNS
cord-010027-r0tl01kq	1388	9	suggests	suggest	VBZ
cord-010027-r0tl01kq	1388	10	that	that	IN
cord-010027-r0tl01kq	1388	11	these	these	DT
cord-010027-r0tl01kq	1388	12	might	may	MD
cord-010027-r0tl01kq	1388	13	be	be	VB
cord-010027-r0tl01kq	1388	14	formed	form	VBN
cord-010027-r0tl01kq	1388	15	in	in	IN
cord-010027-r0tl01kq	1388	16	later	later	JJ
cord-010027-r0tl01kq	1388	17	developmental	developmental	JJ
cord-010027-r0tl01kq	1388	18	stages	stage	NNS
cord-010027-r0tl01kq	1388	19	.	.	.
cord-010027-r0tl01kq	1389	1	The	the	DT
cord-010027-r0tl01kq	1389	2	perineal	perineal	JJ
cord-010027-r0tl01kq	1389	3	body	body	NN
cord-010027-r0tl01kq	1389	4	(	(	-LRB-
cord-010027-r0tl01kq	1389	5	PB	PB	NNP
cord-010027-r0tl01kq	1389	6	)	)	-RRB-
cord-010027-r0tl01kq	1389	7	is	be	VBZ
cord-010027-r0tl01kq	1389	8	poorly	poorly	RB
cord-010027-r0tl01kq	1389	9	understood	understand	VBN
cord-010027-r0tl01kq	1389	10	.	.	.
cord-010027-r0tl01kq	1390	1	In	in	IN
cord-010027-r0tl01kq	1390	2	abdominoperineal	abdominoperineal	NN
cord-010027-r0tl01kq	1390	3	excision	excision	NN
cord-010027-r0tl01kq	1390	4	(	(	-LRB-
cord-010027-r0tl01kq	1390	5	APE	APE	NNP
cord-010027-r0tl01kq	1390	6	)	)	-RRB-
cord-010027-r0tl01kq	1390	7	,	,	,
cord-010027-r0tl01kq	1390	8	there	there	EX
cord-010027-r0tl01kq	1390	9	is	be	VBZ
cord-010027-r0tl01kq	1390	10	no	no	DT
cord-010027-r0tl01kq	1390	11	natural	natural	JJ
cord-010027-r0tl01kq	1390	12	dissection	dissection	NN
cord-010027-r0tl01kq	1390	13	plane	plane	NN
cord-010027-r0tl01kq	1390	14	through	through	IN
cord-010027-r0tl01kq	1390	15	the	the	DT
cord-010027-r0tl01kq	1390	16	PB	PB	NNP
cord-010027-r0tl01kq	1390	17	.	.	.
cord-010027-r0tl01kq	1391	1	Knowledge	knowledge	NN
cord-010027-r0tl01kq	1391	2	of	of	IN
cord-010027-r0tl01kq	1391	3	the	the	DT
cord-010027-r0tl01kq	1391	4	PB	PB	NNP
cord-010027-r0tl01kq	1391	5	is	be	VBZ
cord-010027-r0tl01kq	1391	6	essential	essential	JJ
cord-010027-r0tl01kq	1391	7	to	to	TO
cord-010027-r0tl01kq	1391	8	avoid	avoid	VB
cord-010027-r0tl01kq	1391	9	straying	stray	VBG
cord-010027-r0tl01kq	1391	10	in	in	RP
cord-010027-r0tl01kq	1391	11	to	to	IN
cord-010027-r0tl01kq	1391	12	incorrect	incorrect	JJ
cord-010027-r0tl01kq	1391	13	planes	plane	NNS
cord-010027-r0tl01kq	1391	14	leading	lead	VBG
cord-010027-r0tl01kq	1391	15	to	to	IN
cord-010027-r0tl01kq	1391	16	tumour	tumour	NN
cord-010027-r0tl01kq	1391	17	perforation	perforation	NN
cord-010027-r0tl01kq	1391	18	and	and	CC
cord-010027-r0tl01kq	1391	19	unnecessary	unnecessary	JJ
cord-010027-r0tl01kq	1391	20	urogenital	urogenital	JJ
cord-010027-r0tl01kq	1391	21	and	and	CC
cord-010027-r0tl01kq	1391	22	anorectal	anorectal	JJ
cord-010027-r0tl01kq	1391	23	injuries	injury	NNS
cord-010027-r0tl01kq	1391	24	.	.	.
cord-010027-r0tl01kq	1392	1	This	this	DT
cord-010027-r0tl01kq	1392	2	study	study	NN
cord-010027-r0tl01kq	1392	3	describes	describe	VBZ
cord-010027-r0tl01kq	1392	4	the	the	DT
cord-010027-r0tl01kq	1392	5	anatomy	anatomy	NN
cord-010027-r0tl01kq	1392	6	of	of	IN
cord-010027-r0tl01kq	1392	7	the	the	DT
cord-010027-r0tl01kq	1392	8	PB	PB	NNP
cord-010027-r0tl01kq	1392	9	and	and	CC
cord-010027-r0tl01kq	1392	10	the	the	DT
cord-010027-r0tl01kq	1392	11	implications	implication	NNS
cord-010027-r0tl01kq	1392	12	for	for	IN
cord-010027-r0tl01kq	1392	13	APE	APE	NNP
cord-010027-r0tl01kq	1392	14	.	.	.
cord-010027-r0tl01kq	1393	1	Six	six	CD
cord-010027-r0tl01kq	1393	2	human	human	JJ
cord-010027-r0tl01kq	1393	3	adult	adult	NN
cord-010027-r0tl01kq	1393	4	cadaveric	cadaveric	JJ
cord-010027-r0tl01kq	1393	5	specimens	specimen	NNS
cord-010027-r0tl01kq	1393	6	(	(	-LRB-
cord-010027-r0tl01kq	1393	7	three	three	CD
cord-010027-r0tl01kq	1393	8	males	male	NNS
cord-010027-r0tl01kq	1393	9	,	,	,
cord-010027-r0tl01kq	1393	10	three	three	CD
cord-010027-r0tl01kq	1393	11	females	female	NNS
cord-010027-r0tl01kq	1393	12	)	)	-RRB-
cord-010027-r0tl01kq	1393	13	were	be	VBD
cord-010027-r0tl01kq	1393	14	obtained	obtain	VBN
cord-010027-r0tl01kq	1393	15	from	from	IN
cord-010027-r0tl01kq	1393	16	the	the	DT
cord-010027-r0tl01kq	1393	17	Leeds	Leeds	NNP
cord-010027-r0tl01kq	1393	18	GIFT	GIFT	NNP
cord-010027-r0tl01kq	1393	19	Research	Research	NNP
cord-010027-r0tl01kq	1393	20	Tissue	Tissue	NNP
cord-010027-r0tl01kq	1393	21	Programme	Programme	NNP
cord-010027-r0tl01kq	1393	22	.	.	.
cord-010027-r0tl01kq	1394	1	Paraffin	paraffin	NN
cord-010027-r0tl01kq	1394	2	-	-	HYPH
cord-010027-r0tl01kq	1394	3	embedded	embed	VBN
cord-010027-r0tl01kq	1394	4	mega	mega	NNS
cord-010027-r0tl01kq	1394	5	-	-	NNS
cord-010027-r0tl01kq	1394	6	blocks	block	NNS
cord-010027-r0tl01kq	1394	7	containing	contain	VBG
cord-010027-r0tl01kq	1394	8	the	the	DT
cord-010027-r0tl01kq	1394	9	PB	PB	NNP
cord-010027-r0tl01kq	1394	10	were	be	VBD
cord-010027-r0tl01kq	1394	11	produced	produce	VBN
cord-010027-r0tl01kq	1394	12	and	and	CC
cord-010027-r0tl01kq	1394	13	serially	serially	RB
cord-010027-r0tl01kq	1394	14	sectioned	section	VBN
cord-010027-r0tl01kq	1394	15	at	at	IN
cord-010027-r0tl01kq	1394	16	50	50	CD
cord-010027-r0tl01kq	1394	17	and	and	CC
cord-010027-r0tl01kq	1394	18	250	250	CD
cord-010027-r0tl01kq	1394	19	µm	µm	CD
cord-010027-r0tl01kq	1394	20	intervals	interval	NNS
cord-010027-r0tl01kq	1394	21	.	.	.
cord-010027-r0tl01kq	1395	1	Sections	section	NNS
cord-010027-r0tl01kq	1395	2	were	be	VBD
cord-010027-r0tl01kq	1395	3	stained	stain	VBN
cord-010027-r0tl01kq	1395	4	to	to	TO
cord-010027-r0tl01kq	1395	5	reveal	reveal	VB
cord-010027-r0tl01kq	1395	6	collagen	collagen	NN
cord-010027-r0tl01kq	1395	7	and	and	CC
cord-010027-r0tl01kq	1395	8	elastin	elastin	NN
cord-010027-r0tl01kq	1395	9	,	,	,
cord-010027-r0tl01kq	1395	10	and	and	CC
cord-010027-r0tl01kq	1395	11	with	with	IN
cord-010027-r0tl01kq	1395	12	an	an	DT
cord-010027-r0tl01kq	1395	13	antibody	antibody	NN
cord-010027-r0tl01kq	1395	14	against	against	IN
cord-010027-r0tl01kq	1395	15	α	α	NN
cord-010027-r0tl01kq	1395	16	-	-	HYPH
cord-010027-r0tl01kq	1395	17	smooth	smooth	JJ
cord-010027-r0tl01kq	1395	18	muscle	muscle	NN
cord-010027-r0tl01kq	1395	19	actin	actin	NN
cord-010027-r0tl01kq	1395	20	.	.	.
cord-010027-r0tl01kq	1396	1	The	the	DT
cord-010027-r0tl01kq	1396	2	PB	PB	NNP
cord-010027-r0tl01kq	1396	3	is	be	VBZ
cord-010027-r0tl01kq	1396	4	formed	form	VBN
cord-010027-r0tl01kq	1396	5	of	of	IN
cord-010027-r0tl01kq	1396	6	a	a	DT
cord-010027-r0tl01kq	1396	7	fibromuscular	fibromuscular	JJ
cord-010027-r0tl01kq	1396	8	mass	mass	NN
cord-010027-r0tl01kq	1396	9	,	,	,
cord-010027-r0tl01kq	1396	10	which	which	WDT
cord-010027-r0tl01kq	1396	11	was	be	VBD
cord-010027-r0tl01kq	1396	12	thicker	thick	JJR
cord-010027-r0tl01kq	1396	13	and	and	CC
cord-010027-r0tl01kq	1396	14	wider	wide	JJR
cord-010027-r0tl01kq	1396	15	in	in	IN
cord-010027-r0tl01kq	1396	16	female	female	JJ
cord-010027-r0tl01kq	1396	17	specimens	specimen	NNS
cord-010027-r0tl01kq	1396	18	compared	compare	VBN
cord-010027-r0tl01kq	1396	19	to	to	IN
cord-010027-r0tl01kq	1396	20	males	male	NNS
cord-010027-r0tl01kq	1396	21	,	,	,
cord-010027-r0tl01kq	1396	22	extending	extend	VBG
cord-010027-r0tl01kq	1396	23	from	from	IN
cord-010027-r0tl01kq	1396	24	the	the	DT
cord-010027-r0tl01kq	1396	25	external	external	JJ
cord-010027-r0tl01kq	1396	26	anal	anal	JJ
cord-010027-r0tl01kq	1396	27	sphincter	sphincter	NN
cord-010027-r0tl01kq	1396	28	to	to	IN
cord-010027-r0tl01kq	1396	29	the	the	DT
cord-010027-r0tl01kq	1396	30	rectogenital	rectogenital	NN
cord-010027-r0tl01kq	1396	31	septum	septum	NN
cord-010027-r0tl01kq	1396	32	.	.	.
cord-010027-r0tl01kq	1397	1	Muscles	muscle	NNS
cord-010027-r0tl01kq	1397	2	from	from	IN
cord-010027-r0tl01kq	1397	3	the	the	DT
cord-010027-r0tl01kq	1397	4	urogenital	urogenital	JJ
cord-010027-r0tl01kq	1397	5	diaphragm	diaphragm	NN
cord-010027-r0tl01kq	1397	6	and	and	CC
cord-010027-r0tl01kq	1397	7	anterior	anterior	JJ
cord-010027-r0tl01kq	1397	8	rectal	rectal	JJ
cord-010027-r0tl01kq	1397	9	wall	wall	NN
cord-010027-r0tl01kq	1397	10	anchored	anchor	VBN
cord-010027-r0tl01kq	1397	11	into	into	IN
cord-010027-r0tl01kq	1397	12	the	the	DT
cord-010027-r0tl01kq	1397	13	PB	PB	NNP
cord-010027-r0tl01kq	1397	14	.	.	.
cord-010027-r0tl01kq	1398	1	The	the	DT
cord-010027-r0tl01kq	1398	2	longitudinal	longitudinal	JJ
cord-010027-r0tl01kq	1398	3	muscle	muscle	NN
cord-010027-r0tl01kq	1398	4	(	(	-LRB-
cord-010027-r0tl01kq	1398	5	LM	LM	NNP
cord-010027-r0tl01kq	1398	6	)	)	-RRB-
cord-010027-r0tl01kq	1398	7	of	of	IN
cord-010027-r0tl01kq	1398	8	the	the	DT
cord-010027-r0tl01kq	1398	9	rectal	rectal	JJ
cord-010027-r0tl01kq	1398	10	muscularis	muscularis	NNP
cord-010027-r0tl01kq	1398	11	propria	propria	NN
cord-010027-r0tl01kq	1398	12	extended	extend	VBN
cord-010027-r0tl01kq	1398	13	in	in	IN
cord-010027-r0tl01kq	1398	14	anterolateral	anterolateral	JJ
cord-010027-r0tl01kq	1398	15	directions	direction	NNS
cord-010027-r0tl01kq	1398	16	and	and	CC
cord-010027-r0tl01kq	1398	17	intertwined	intertwine	VBN
cord-010027-r0tl01kq	1398	18	with	with	IN
cord-010027-r0tl01kq	1398	19	the	the	DT
cord-010027-r0tl01kq	1398	20	somatic	somatic	JJ
cord-010027-r0tl01kq	1398	21	pelvic	pelvic	JJ
cord-010027-r0tl01kq	1398	22	floor	floor	NN
cord-010027-r0tl01kq	1398	23	muscles	muscle	NNS
cord-010027-r0tl01kq	1398	24	to	to	TO
cord-010027-r0tl01kq	1398	25	create	create	VB
cord-010027-r0tl01kq	1398	26	strong	strong	JJ
cord-010027-r0tl01kq	1398	27	fixation	fixation	NN
cord-010027-r0tl01kq	1398	28	of	of	IN
cord-010027-r0tl01kq	1398	29	the	the	DT
cord-010027-r0tl01kq	1398	30	anorectum	anorectum	NNP
cord-010027-r0tl01kq	1398	31	.	.	.
cord-010027-r0tl01kq	1399	1	The	the	DT
cord-010027-r0tl01kq	1399	2	LM	LM	NNP
cord-010027-r0tl01kq	1399	3	plays	play	VBZ
cord-010027-r0tl01kq	1399	4	a	a	DT
cord-010027-r0tl01kq	1399	5	dominant	dominant	JJ
cord-010027-r0tl01kq	1399	6	role	role	NN
cord-010027-r0tl01kq	1399	7	in	in	IN
cord-010027-r0tl01kq	1399	8	the	the	DT
cord-010027-r0tl01kq	1399	9	formation	formation	NN
cord-010027-r0tl01kq	1399	10	of	of	IN
cord-010027-r0tl01kq	1399	11	the	the	DT
cord-010027-r0tl01kq	1399	12	PB	PB	NNP
cord-010027-r0tl01kq	1399	13	.	.	.
cord-010027-r0tl01kq	1400	1	Surgeons	surgeon	NNS
cord-010027-r0tl01kq	1400	2	should	should	MD
cord-010027-r0tl01kq	1400	3	be	be	VB
cord-010027-r0tl01kq	1400	4	aware	aware	JJ
cord-010027-r0tl01kq	1400	5	of	of	IN
cord-010027-r0tl01kq	1400	6	the	the	DT
cord-010027-r0tl01kq	1400	7	complex	complex	JJ
cord-010027-r0tl01kq	1400	8	course	course	NN
cord-010027-r0tl01kq	1400	9	of	of	IN
cord-010027-r0tl01kq	1400	10	the	the	DT
cord-010027-r0tl01kq	1400	11	LM	LM	NNP
cord-010027-r0tl01kq	1400	12	through	through	IN
cord-010027-r0tl01kq	1400	13	the	the	DT
cord-010027-r0tl01kq	1400	14	PB	PB	NNP
cord-010027-r0tl01kq	1400	15	to	to	TO
cord-010027-r0tl01kq	1400	16	prevent	prevent	VB
cord-010027-r0tl01kq	1400	17	injuries	injury	NNS
cord-010027-r0tl01kq	1400	18	to	to	IN
cord-010027-r0tl01kq	1400	19	the	the	DT
cord-010027-r0tl01kq	1400	20	urogenital	urogenital	JJ
cord-010027-r0tl01kq	1400	21	organs	organ	NNS
cord-010027-r0tl01kq	1400	22	and	and	CC
cord-010027-r0tl01kq	1400	23	perforation	perforation	NN
cord-010027-r0tl01kq	1400	24	of	of	IN
cord-010027-r0tl01kq	1400	25	the	the	DT
cord-010027-r0tl01kq	1400	26	anterior	anterior	JJ
cord-010027-r0tl01kq	1400	27	rectal	rectal	JJ
cord-010027-r0tl01kq	1400	28	wall	wall	NN
cord-010027-r0tl01kq	1400	29	.	.	.
cord-010027-r0tl01kq	1401	1	The	the	DT
cord-010027-r0tl01kq	1401	2	perineal	perineal	JJ
cord-010027-r0tl01kq	1401	3	phase	phase	NN
cord-010027-r0tl01kq	1401	4	of	of	IN
cord-010027-r0tl01kq	1401	5	an	an	DT
cord-010027-r0tl01kq	1401	6	APE	ape	NN
cord-010027-r0tl01kq	1401	7	starts	start	VBZ
cord-010027-r0tl01kq	1401	8	with	with	IN
cord-010027-r0tl01kq	1401	9	excellent	excellent	JJ
cord-010027-r0tl01kq	1401	10	exposure	exposure	NN
cord-010027-r0tl01kq	1401	11	followed	follow	VBN
cord-010027-r0tl01kq	1401	12	by	by	IN
cord-010027-r0tl01kq	1401	13	proper	proper	JJ
cord-010027-r0tl01kq	1401	14	tension	tension	NN
cord-010027-r0tl01kq	1401	15	on	on	IN
cord-010027-r0tl01kq	1401	16	the	the	DT
cord-010027-r0tl01kq	1401	17	PB	PB	NNP
cord-010027-r0tl01kq	1401	18	to	to	TO
cord-010027-r0tl01kq	1401	19	allow	allow	VB
cord-010027-r0tl01kq	1401	20	safe	safe	JJ
cord-010027-r0tl01kq	1401	21	dissection	dissection	NN
cord-010027-r0tl01kq	1401	22	through	through	IN
cord-010027-r0tl01kq	1401	23	the	the	DT
cord-010027-r0tl01kq	1401	24	densely	densely	RB
cord-010027-r0tl01kq	1401	25	-	-	HYPH
cord-010027-r0tl01kq	1401	26	packed	pack	VBN
cord-010027-r0tl01kq	1401	27	fibromuscular	fibromuscular	JJ
cord-010027-r0tl01kq	1401	28	mass	mass	NN
cord-010027-r0tl01kq	1401	29	.	.	.
cord-010027-r0tl01kq	1402	1	Introduction	introduction	NN
cord-010027-r0tl01kq	1402	2	:	:	:
cord-010027-r0tl01kq	1402	3	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1402	4	is	be	VBZ
cord-010027-r0tl01kq	1402	5	a	a	DT
cord-010027-r0tl01kq	1402	6	proliferation	proliferation	NN
cord-010027-r0tl01kq	1402	7	marker	marker	NN
cord-010027-r0tl01kq	1402	8	that	that	WDT
cord-010027-r0tl01kq	1402	9	is	be	VBZ
cord-010027-r0tl01kq	1402	10	exclusively	exclusively	RB
cord-010027-r0tl01kq	1402	11	present	present	JJ
cord-010027-r0tl01kq	1402	12	in	in	IN
cord-010027-r0tl01kq	1402	13	dividing	divide	VBG
cord-010027-r0tl01kq	1402	14	cells	cell	NNS
cord-010027-r0tl01kq	1402	15	and	and	CC
cord-010027-r0tl01kq	1402	16	absent	absent	JJ
cord-010027-r0tl01kq	1402	17	in	in	IN
cord-010027-r0tl01kq	1402	18	resting	rest	VBG
cord-010027-r0tl01kq	1402	19	cells	cell	NNS
cord-010027-r0tl01kq	1402	20	.	.	.
cord-010027-r0tl01kq	1403	1	Its	-PRON-	PRP$
cord-010027-r0tl01kq	1403	2	expression	expression	NN
cord-010027-r0tl01kq	1403	3	has	have	VBZ
cord-010027-r0tl01kq	1403	4	already	already	RB
cord-010027-r0tl01kq	1403	5	been	be	VBN
cord-010027-r0tl01kq	1403	6	studied	study	VBN
cord-010027-r0tl01kq	1403	7	in	in	IN
cord-010027-r0tl01kq	1403	8	different	different	JJ
cord-010027-r0tl01kq	1403	9	cancers	cancer	NNS
cord-010027-r0tl01kq	1403	10	and	and	CC
cord-010027-r0tl01kq	1403	11	used	use	VBD
cord-010027-r0tl01kq	1403	12	to	to	TO
cord-010027-r0tl01kq	1403	13	understand	understand	VB
cord-010027-r0tl01kq	1403	14	the	the	DT
cord-010027-r0tl01kq	1403	15	cellular	cellular	JJ
cord-010027-r0tl01kq	1403	16	organisation	organisation	NN
cord-010027-r0tl01kq	1403	17	of	of	IN
cord-010027-r0tl01kq	1403	18	Barrett	Barrett	NNP
cord-010027-r0tl01kq	1403	19	's	's	POS
cord-010027-r0tl01kq	1403	20	epithelium	epithelium	NN
cord-010027-r0tl01kq	1403	21	(	(	-LRB-
cord-010027-r0tl01kq	1403	22	Lavery	Lavery	NNP
cord-010027-r0tl01kq	1403	23	2014	2014	CD
cord-010027-r0tl01kq	1403	24	)	)	-RRB-
cord-010027-r0tl01kq	1403	25	.	.	.
cord-010027-r0tl01kq	1404	1	However	however	RB
cord-010027-r0tl01kq	1404	2	,	,	,
cord-010027-r0tl01kq	1404	3	very	very	RB
cord-010027-r0tl01kq	1404	4	little	little	JJ
cord-010027-r0tl01kq	1404	5	is	be	VBZ
cord-010027-r0tl01kq	1404	6	known	know	VBN
cord-010027-r0tl01kq	1404	7	about	about	IN
cord-010027-r0tl01kq	1404	8	the	the	DT
cord-010027-r0tl01kq	1404	9	cellular	cellular	JJ
cord-010027-r0tl01kq	1404	10	organisation	organisation	NN
cord-010027-r0tl01kq	1404	11	based	base	VBN
cord-010027-r0tl01kq	1404	12	on	on	IN
cord-010027-r0tl01kq	1404	13	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1404	14	expression	expression	NN
cord-010027-r0tl01kq	1404	15	patterns	pattern	NNS
cord-010027-r0tl01kq	1404	16	in	in	IN
cord-010027-r0tl01kq	1404	17	upper	upper	JJ
cord-010027-r0tl01kq	1404	18	GI	gi	NN
cord-010027-r0tl01kq	1404	19	sequence	sequence	NN
cord-010027-r0tl01kq	1404	20	.	.	.
cord-010027-r0tl01kq	1405	1	This	this	DT
cord-010027-r0tl01kq	1405	2	study	study	NN
cord-010027-r0tl01kq	1405	3	aims	aim	VBZ
cord-010027-r0tl01kq	1405	4	to	to	TO
cord-010027-r0tl01kq	1405	5	examine	examine	VB
cord-010027-r0tl01kq	1405	6	the	the	DT
cord-010027-r0tl01kq	1405	7	cellular	cellular	JJ
cord-010027-r0tl01kq	1405	8	organisation	organisation	NN
cord-010027-r0tl01kq	1405	9	as	as	IN
cord-010027-r0tl01kq	1405	10	defined	define	VBN
cord-010027-r0tl01kq	1405	11	by	by	IN
cord-010027-r0tl01kq	1405	12	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1405	13	expression	expression	NN
cord-010027-r0tl01kq	1405	14	patterns	pattern	NNS
cord-010027-r0tl01kq	1405	15	in	in	IN
cord-010027-r0tl01kq	1405	16	upper	upper	JJ
cord-010027-r0tl01kq	1405	17	GI	gi	NN
cord-010027-r0tl01kq	1405	18	cancer	cancer	NN
cord-010027-r0tl01kq	1405	19	sequence	sequence	NN
cord-010027-r0tl01kq	1405	20	.	.	.
cord-010027-r0tl01kq	1406	1	Methods	method	NNS
cord-010027-r0tl01kq	1406	2	:	:	:
cord-010027-r0tl01kq	1406	3	Ki67	ki67	ADD
cord-010027-r0tl01kq	1407	1	expression	expression	NN
cord-010027-r0tl01kq	1407	2	within	within	IN
cord-010027-r0tl01kq	1407	3	Barrett	Barrett	NNP
cord-010027-r0tl01kq	1407	4	's	's	POS
cord-010027-r0tl01kq	1407	5	crypts	crypt	NNS
cord-010027-r0tl01kq	1407	6	was	be	VBD
cord-010027-r0tl01kq	1407	7	assessed	assess	VBN
cord-010027-r0tl01kq	1407	8	in	in	IN
cord-010027-r0tl01kq	1407	9	40	40	CD
cord-010027-r0tl01kq	1407	10	cases	case	NNS
cord-010027-r0tl01kq	1407	11	(	(	-LRB-
cord-010027-r0tl01kq	1407	12	NBDE	NBDE	NNP
cord-010027-r0tl01kq	1407	13	11	11	CD
cord-010027-r0tl01kq	1407	14	,	,	,
cord-010027-r0tl01kq	1407	15	LGD	LGD	NNP
cord-010027-r0tl01kq	1407	16	15	15	CD
cord-010027-r0tl01kq	1407	17	,	,	,
cord-010027-r0tl01kq	1407	18	HGD	HGD	NNP
cord-010027-r0tl01kq	1407	19	14	14	CD
cord-010027-r0tl01kq	1407	20	)	)	-RRB-
cord-010027-r0tl01kq	1407	21	.	.	.
cord-010027-r0tl01kq	1408	1	The	the	DT
cord-010027-r0tl01kq	1408	2	Barrett	Barrett	NNP
cord-010027-r0tl01kq	1408	3	's	's	POS
cord-010027-r0tl01kq	1408	4	crypts	crypt	NNS
cord-010027-r0tl01kq	1408	5	were	be	VBD
cord-010027-r0tl01kq	1408	6	divided	divide	VBN
cord-010027-r0tl01kq	1408	7	into	into	IN
cord-010027-r0tl01kq	1408	8	three	three	CD
cord-010027-r0tl01kq	1408	9	equal	equal	JJ
cord-010027-r0tl01kq	1408	10	regions	region	NNS
cord-010027-r0tl01kq	1408	11	:	:	:
cord-010027-r0tl01kq	1408	12	crypt	crypt	NN
cord-010027-r0tl01kq	1408	13	base	base	NN
cord-010027-r0tl01kq	1408	14	(	(	-LRB-
cord-010027-r0tl01kq	1408	15	bottom	bottom	NN
cord-010027-r0tl01kq	1408	16	third	third	RB
cord-010027-r0tl01kq	1408	17	)	)	-RRB-
cord-010027-r0tl01kq	1408	18	,	,	,
cord-010027-r0tl01kq	1408	19	middle	middle	JJ
cord-010027-r0tl01kq	1408	20	region	region	NN
cord-010027-r0tl01kq	1408	21	and	and	CC
cord-010027-r0tl01kq	1408	22	the	the	DT
cord-010027-r0tl01kq	1408	23	surface	surface	NN
cord-010027-r0tl01kq	1408	24	(	(	-LRB-
cord-010027-r0tl01kq	1408	25	upper	upper	JJ
cord-010027-r0tl01kq	1408	26	third	third	NN
cord-010027-r0tl01kq	1408	27	)	)	-RRB-
cord-010027-r0tl01kq	1408	28	,	,	,
cord-010027-r0tl01kq	1408	29	respectively	respectively	RB
cord-010027-r0tl01kq	1408	30	.	.	.
cord-010027-r0tl01kq	1409	1	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1409	2	was	be	VBD
cord-010027-r0tl01kq	1409	3	scored	score	VBN
cord-010027-r0tl01kq	1409	4	using	use	VBG
cord-010027-r0tl01kq	1409	5	the	the	DT
cord-010027-r0tl01kq	1409	6	Allred	Allred	NNP
cord-010027-r0tl01kq	1409	7	system	system	NN
cord-010027-r0tl01kq	1409	8	and	and	CC
cord-010027-r0tl01kq	1409	9	analysed	analyse	VBD
cord-010027-r0tl01kq	1409	10	using	use	VBG
cord-010027-r0tl01kq	1409	11	one	one	CD
cord-010027-r0tl01kq	1409	12	-	-	HYPH
cord-010027-r0tl01kq	1409	13	way	way	NN
cord-010027-r0tl01kq	1409	14	ANOVA	anova	NN
cord-010027-r0tl01kq	1409	15	with	with	IN
cord-010027-r0tl01kq	1409	16	Bonferroni	Bonferroni	NNP
cord-010027-r0tl01kq	1409	17	post	post	VB
cord-010027-r0tl01kq	1409	18	-	-	JJ
cord-010027-r0tl01kq	1409	19	hoc	hoc	JJ
cord-010027-r0tl01kq	1409	20	analysis	analysis	NN
cord-010027-r0tl01kq	1409	21	.	.	.
cord-010027-r0tl01kq	1410	1	Results	result	NNS
cord-010027-r0tl01kq	1410	2	:	:	:
cord-010027-r0tl01kq	1411	1	One	one	CD
cord-010027-r0tl01kq	1411	2	-	-	HYPH
cord-010027-r0tl01kq	1411	3	way	way	NN
cord-010027-r0tl01kq	1411	4	ANOVA	ANOVA	NNP
cord-010027-r0tl01kq	1411	5	showed	show	VBD
cord-010027-r0tl01kq	1411	6	significant	significant	JJ
cord-010027-r0tl01kq	1411	7	difference	difference	NN
cord-010027-r0tl01kq	1411	8	across	across	IN
cord-010027-r0tl01kq	1411	9	the	the	DT
cord-010027-r0tl01kq	1411	10	three	three	CD
cord-010027-r0tl01kq	1411	11	groups	group	NNS
cord-010027-r0tl01kq	1411	12	(	(	-LRB-
cord-010027-r0tl01kq	1411	13	p	p	NN
cord-010027-r0tl01kq	1411	14	<	<	XX
cord-010027-r0tl01kq	1411	15	0.0001	0.0001	CD
cord-010027-r0tl01kq	1411	16	)	)	-RRB-
cord-010027-r0tl01kq	1411	17	.	.	.
cord-010027-r0tl01kq	1412	1	Bonferroni	bonferroni	RB
cord-010027-r0tl01kq	1412	2	post	post	VB
cord-010027-r0tl01kq	1412	3	-	-	JJ
cord-010027-r0tl01kq	1412	4	hoc	hoc	JJ
cord-010027-r0tl01kq	1412	5	analysis	analysis	NN
cord-010027-r0tl01kq	1412	6	showed	show	VBD
cord-010027-r0tl01kq	1412	7	significant	significant	JJ
cord-010027-r0tl01kq	1412	8	difference	difference	NN
cord-010027-r0tl01kq	1412	9	in	in	IN
cord-010027-r0tl01kq	1412	10	the	the	DT
cord-010027-r0tl01kq	1412	11	surface	surface	NN
cord-010027-r0tl01kq	1412	12	architecture	architecture	NN
cord-010027-r0tl01kq	1412	13	between	between	IN
cord-010027-r0tl01kq	1412	14	NBDE	NBDE	NNP
cord-010027-r0tl01kq	1412	15	and	and	CC
cord-010027-r0tl01kq	1412	16	HGD	hgd	NN
cord-010027-r0tl01kq	1412	17	(	(	-LRB-
cord-010027-r0tl01kq	1412	18	p	p	NN
cord-010027-r0tl01kq	1412	19	<	<	XX
cord-010027-r0tl01kq	1412	20	0.0001	0.0001	CD
cord-010027-r0tl01kq	1412	21	)	)	-RRB-
cord-010027-r0tl01kq	1412	22	and	and	CC
cord-010027-r0tl01kq	1412	23	LGD	LGD	NNP
cord-010027-r0tl01kq	1412	24	and	and	CC
cord-010027-r0tl01kq	1412	25	HGD	HGD	NNP
cord-010027-r0tl01kq	1412	26	(	(	-LRB-
cord-010027-r0tl01kq	1412	27	p	p	NN
cord-010027-r0tl01kq	1412	28	<	<	XX
cord-010027-r0tl01kq	1412	29	0.0001	0.0001	CD
cord-010027-r0tl01kq	1412	30	)	)	-RRB-
cord-010027-r0tl01kq	1412	31	.	.	.
cord-010027-r0tl01kq	1413	1	For	for	IN
cord-010027-r0tl01kq	1413	2	the	the	DT
cord-010027-r0tl01kq	1413	3	middle	middle	JJ
cord-010027-r0tl01kq	1413	4	region	region	NN
cord-010027-r0tl01kq	1413	5	,	,	,
cord-010027-r0tl01kq	1413	6	although	although	IN
cord-010027-r0tl01kq	1413	7	there	there	EX
cord-010027-r0tl01kq	1413	8	was	be	VBD
cord-010027-r0tl01kq	1413	9	no	no	DT
cord-010027-r0tl01kq	1413	10	statistical	statistical	JJ
cord-010027-r0tl01kq	1413	11	significance	significance	NN
cord-010027-r0tl01kq	1413	12	between	between	IN
cord-010027-r0tl01kq	1413	13	the	the	DT
cord-010027-r0tl01kq	1413	14	groups	group	NNS
cord-010027-r0tl01kq	1413	15	,	,	,
cord-010027-r0tl01kq	1413	16	NBDE	NBDE	NNP
cord-010027-r0tl01kq	1413	17	and	and	CC
cord-010027-r0tl01kq	1413	18	LGD	LGD	NNP
cord-010027-r0tl01kq	1413	19	and	and	CC
cord-010027-r0tl01kq	1413	20	LGD	LGD	NNP
cord-010027-r0tl01kq	1413	21	and	and	CC
cord-010027-r0tl01kq	1413	22	HGD	HGD	NNP
cord-010027-r0tl01kq	1413	23	showed	show	VBD
cord-010027-r0tl01kq	1413	24	statistical	statistical	JJ
cord-010027-r0tl01kq	1413	25	trends	trend	NNS
cord-010027-r0tl01kq	1414	1	(	(	-LRB-
cord-010027-r0tl01kq	1414	2	p	p	NN
cord-010027-r0tl01kq	1414	3	=	=	SYM
cord-010027-r0tl01kq	1414	4	0.079	0.079	CD
cord-010027-r0tl01kq	1414	5	and	and	CC
cord-010027-r0tl01kq	1414	6	p	p	NN
cord-010027-r0tl01kq	1414	7	=	=	SYM
cord-010027-r0tl01kq	1414	8	0.089	0.089	CD
cord-010027-r0tl01kq	1414	9	respectively	respectively	RB
cord-010027-r0tl01kq	1414	10	)	)	-RRB-
cord-010027-r0tl01kq	1414	11	.	.	.
cord-010027-r0tl01kq	1415	1	For	for	IN
cord-010027-r0tl01kq	1415	2	the	the	DT
cord-010027-r0tl01kq	1415	3	basal	basal	NN
cord-010027-r0tl01kq	1415	4	compartment	compartment	NN
cord-010027-r0tl01kq	1415	5	there	there	EX
cord-010027-r0tl01kq	1415	6	was	be	VBD
cord-010027-r0tl01kq	1415	7	significant	significant	JJ
cord-010027-r0tl01kq	1415	8	difference	difference	NN
cord-010027-r0tl01kq	1415	9	between	between	IN
cord-010027-r0tl01kq	1415	10	NBDE	NBDE	NNP
cord-010027-r0tl01kq	1415	11	and	and	CC
cord-010027-r0tl01kq	1415	12	LGD	LGD	NNP
cord-010027-r0tl01kq	1415	13	(	(	-LRB-
cord-010027-r0tl01kq	1415	14	p	p	NN
cord-010027-r0tl01kq	1415	15	=	=	SYM
cord-010027-r0tl01kq	1415	16	0.035	0.035	CD
cord-010027-r0tl01kq	1415	17	)	)	-RRB-
cord-010027-r0tl01kq	1415	18	.	.	.
cord-010027-r0tl01kq	1416	1	This	this	DT
cord-010027-r0tl01kq	1416	2	study	study	NN
cord-010027-r0tl01kq	1416	3	showed	show	VBD
cord-010027-r0tl01kq	1416	4	for	for	IN
cord-010027-r0tl01kq	1416	5	the	the	DT
cord-010027-r0tl01kq	1416	6	first	first	JJ
cord-010027-r0tl01kq	1416	7	time	time	NN
cord-010027-r0tl01kq	1416	8	a	a	DT
cord-010027-r0tl01kq	1416	9	significant	significant	JJ
cord-010027-r0tl01kq	1416	10	difference	difference	NN
cord-010027-r0tl01kq	1416	11	in	in	IN
cord-010027-r0tl01kq	1416	12	the	the	DT
cord-010027-r0tl01kq	1416	13	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1416	14	expression	expression	NN
cord-010027-r0tl01kq	1416	15	between	between	IN
cord-010027-r0tl01kq	1416	16	NBDE	NBDE	NNP
cord-010027-r0tl01kq	1416	17	,	,	,
cord-010027-r0tl01kq	1416	18	LGD	LGD	NNP
cord-010027-r0tl01kq	1416	19	and	and	CC
cord-010027-r0tl01kq	1416	20	HGD	HGD	NNP
cord-010027-r0tl01kq	1416	21	in	in	IN
cord-010027-r0tl01kq	1416	22	the	the	DT
cord-010027-r0tl01kq	1416	23	basal	basal	NN
cord-010027-r0tl01kq	1416	24	and	and	CC
cord-010027-r0tl01kq	1416	25	surface	surface	NN
cord-010027-r0tl01kq	1416	26	regions	region	NNS
cord-010027-r0tl01kq	1416	27	.	.	.
cord-010027-r0tl01kq	1417	1	Middle	middle	JJ
cord-010027-r0tl01kq	1417	2	compartments	compartment	NNS
cord-010027-r0tl01kq	1417	3	showed	show	VBD
cord-010027-r0tl01kq	1417	4	trends	trend	NNS
cord-010027-r0tl01kq	1417	5	but	but	CC
cord-010027-r0tl01kq	1417	6	additional	additional	JJ
cord-010027-r0tl01kq	1417	7	NDBE	NDBE	NNP
cord-010027-r0tl01kq	1417	8	,	,	,
cord-010027-r0tl01kq	1417	9	LGD	LGD	NNP
cord-010027-r0tl01kq	1417	10	and	and	CC
cord-010027-r0tl01kq	1417	11	HGD	HGD	NNP
cord-010027-r0tl01kq	1417	12	groups	group	NNS
cord-010027-r0tl01kq	1417	13	need	need	VBP
cord-010027-r0tl01kq	1417	14	to	to	TO
cord-010027-r0tl01kq	1417	15	be	be	VB
cord-010027-r0tl01kq	1417	16	analysed	analyse	VBN
cord-010027-r0tl01kq	1417	17	to	to	TO
cord-010027-r0tl01kq	1417	18	increase	increase	VB
cord-010027-r0tl01kq	1417	19	the	the	DT
cord-010027-r0tl01kq	1417	20	statistical	statistical	JJ
cord-010027-r0tl01kq	1417	21	power	power	NN
cord-010027-r0tl01kq	1417	22	.	.	.
cord-010027-r0tl01kq	1418	1	The	the	DT
cord-010027-r0tl01kq	1418	2	results	result	NNS
cord-010027-r0tl01kq	1418	3	warrant	warrant	VBP
cord-010027-r0tl01kq	1418	4	further	further	JJ
cord-010027-r0tl01kq	1418	5	molecular	molecular	JJ
cord-010027-r0tl01kq	1418	6	analysis	analysis	NN
cord-010027-r0tl01kq	1418	7	between	between	IN
cord-010027-r0tl01kq	1418	8	the	the	DT
cord-010027-r0tl01kq	1418	9	various	various	JJ
cord-010027-r0tl01kq	1418	10	groups	group	NNS
cord-010027-r0tl01kq	1418	11	and	and	CC
cord-010027-r0tl01kq	1418	12	show	show	VB
cord-010027-r0tl01kq	1418	13	a	a	DT
cord-010027-r0tl01kq	1418	14	clear	clear	JJ
cord-010027-r0tl01kq	1418	15	role	role	NN
cord-010027-r0tl01kq	1418	16	for	for	IN
cord-010027-r0tl01kq	1418	17	proliferation	proliferation	NN
cord-010027-r0tl01kq	1418	18	in	in	IN
cord-010027-r0tl01kq	1418	19	the	the	DT
cord-010027-r0tl01kq	1418	20	maintenance	maintenance	NN
cord-010027-r0tl01kq	1418	21	of	of	IN
cord-010027-r0tl01kq	1418	22	the	the	DT
cord-010027-r0tl01kq	1418	23	cellular	cellular	JJ
cord-010027-r0tl01kq	1418	24	architecture	architecture	NN
cord-010027-r0tl01kq	1418	25	and	and	CC
cord-010027-r0tl01kq	1418	26	organisation	organisation	NN
cord-010027-r0tl01kq	1418	27	across	across	IN
cord-010027-r0tl01kq	1418	28	the	the	DT
cord-010027-r0tl01kq	1418	29	upper	upper	JJ
cord-010027-r0tl01kq	1418	30	GI	GI	NNP
cord-010027-r0tl01kq	1418	31	groups	group	NNS
cord-010027-r0tl01kq	1418	32	which	which	WDT
cord-010027-r0tl01kq	1418	33	might	may	MD
cord-010027-r0tl01kq	1418	34	help	help	VB
cord-010027-r0tl01kq	1418	35	in	in	IN
cord-010027-r0tl01kq	1418	36	the	the	DT
cord-010027-r0tl01kq	1418	37	understanding	understanding	NN
cord-010027-r0tl01kq	1418	38	of	of	IN
cord-010027-r0tl01kq	1418	39	the	the	DT
cord-010027-r0tl01kq	1418	40	origin	origin	NN
cord-010027-r0tl01kq	1418	41	and	and	CC
cord-010027-r0tl01kq	1418	42	development	development	NN
cord-010027-r0tl01kq	1418	43	of	of	IN
cord-010027-r0tl01kq	1418	44	OAC	OAC	NNP
cord-010027-r0tl01kq	1418	45	.	.	.
cord-010027-r0tl01kq	1419	1	•	•	NNP
cord-010027-r0tl01kq	1420	1	Frequency	frequency	NN
cord-010027-r0tl01kq	1420	2	of	of	IN
cord-010027-r0tl01kq	1420	3	serosal	serosal	NN
cord-010027-r0tl01kq	1420	4	involvement	involvement	NN
cord-010027-r0tl01kq	1420	5	in	in	IN
cord-010027-r0tl01kq	1420	6	rectal	rectal	JJ
cord-010027-r0tl01kq	1420	7	cancers	cancer	NNS
cord-010027-r0tl01kq	1420	8	(	(	-LRB-
cord-010027-r0tl01kq	1420	9	suggested	suggest	VBN
cord-010027-r0tl01kq	1420	10	contributing	contributing	NN
cord-010027-r0tl01kq	1420	11	factors	factor	NNS
cord-010027-r0tl01kq	1420	12	for	for	IN
cord-010027-r0tl01kq	1420	13	this	this	DT
cord-010027-r0tl01kq	1420	14	include	include	VBP
cord-010027-r0tl01kq	1420	15	effect	effect	NN
cord-010027-r0tl01kq	1420	16	of	of	IN
cord-010027-r0tl01kq	1420	17	pre	pre	JJ
cord-010027-r0tl01kq	1420	18	-	-	JJ
cord-010027-r0tl01kq	1420	19	operative	operative	JJ
cord-010027-r0tl01kq	1420	20	therapy	therapy	NN
cord-010027-r0tl01kq	1420	21	,	,	,
cord-010027-r0tl01kq	1420	22	tumour	tumour	NN
cord-010027-r0tl01kq	1420	23	regression	regression	NN
cord-010027-r0tl01kq	1420	24	and	and	CC
cord-010027-r0tl01kq	1420	25	recent	recent	JJ
cord-010027-r0tl01kq	1420	26	changes	change	NNS
cord-010027-r0tl01kq	1420	27	in	in	IN
cord-010027-r0tl01kq	1420	28	surgical	surgical	JJ
cord-010027-r0tl01kq	1420	29	practice	practice	NN
cord-010027-r0tl01kq	1420	30	)	)	-RRB-
cord-010027-r0tl01kq	1420	31	.	.	.
cord-010027-r0tl01kq	1421	1	•	•	NNP
cord-010027-r0tl01kq	1422	1	Turnaround	turnaround	NN
cord-010027-r0tl01kq	1422	2	times	time	NNS
cord-010027-r0tl01kq	1422	3	:	:	:
cord-010027-r0tl01kq	1422	4	suggested	suggest	VBN
cord-010027-r0tl01kq	1422	5	contributing	contributing	NN
cord-010027-r0tl01kq	1422	6	factors	factor	NNS
cord-010027-r0tl01kq	1422	7	include	include	VBP
cord-010027-r0tl01kq	1422	8	increased	increase	VBN
cord-010027-r0tl01kq	1422	9	departmental	departmental	JJ
cord-010027-r0tl01kq	1422	10	workload	workload	NN
cord-010027-r0tl01kq	1422	11	,	,	,
cord-010027-r0tl01kq	1422	12	retirements	retirement	NNS
cord-010027-r0tl01kq	1422	13	and	and	CC
cord-010027-r0tl01kq	1422	14	reduced	reduce	VBN
cord-010027-r0tl01kq	1422	15	reporting	reporting	NN
cord-010027-r0tl01kq	1422	16	capacity	capacity	NN
cord-010027-r0tl01kq	1422	17	.	.	.
cord-010027-r0tl01kq	1423	1	The	the	DT
cord-010027-r0tl01kq	1423	2	following	following	JJ
cord-010027-r0tl01kq	1423	3	action	action	NN
cord-010027-r0tl01kq	1423	4	plan	plan	NN
cord-010027-r0tl01kq	1423	5	was	be	VBD
cord-010027-r0tl01kq	1423	6	implemented	implement	VBN
cord-010027-r0tl01kq	1423	7	to	to	TO
cord-010027-r0tl01kq	1423	8	improve	improve	VB
cord-010027-r0tl01kq	1423	9	compliance	compliance	NN
cord-010027-r0tl01kq	1423	10	with	with	IN
cord-010027-r0tl01kq	1423	11	standards	standard	NNS
cord-010027-r0tl01kq	1423	12	:	:	:
cord-010027-r0tl01kq	1424	1	•	•	NNP
cord-010027-r0tl01kq	1425	1	Ensure	ensure	VB
cord-010027-r0tl01kq	1425	2	all	all	DT
cord-010027-r0tl01kq	1425	3	pathologists	pathologist	NNS
cord-010027-r0tl01kq	1425	4	are	be	VBP
cord-010027-r0tl01kq	1425	5	aware	aware	JJ
cord-010027-r0tl01kq	1425	6	of	of	IN
cord-010027-r0tl01kq	1425	7	results	result	NNS
cord-010027-r0tl01kq	1425	8	via	via	IN
cord-010027-r0tl01kq	1425	9	presentation	presentation	NN
cord-010027-r0tl01kq	1425	10	/	/	SYM
cord-010027-r0tl01kq	1425	11	dissemination	dissemination	NN
cord-010027-r0tl01kq	1425	12	of	of	IN
cord-010027-r0tl01kq	1425	13	audit	audit	NN
cord-010027-r0tl01kq	1425	14	report	report	NN
cord-010027-r0tl01kq	1426	1	•	•	NNP
cord-010027-r0tl01kq	1426	2	Identify	identify	VB
cord-010027-r0tl01kq	1426	3	issues	issue	NNS
cord-010027-r0tl01kq	1426	4	affecting	affect	VBG
cord-010027-r0tl01kq	1426	5	turn	turn	NN
cord-010027-r0tl01kq	1426	6	-	-	HYPH
cord-010027-r0tl01kq	1426	7	around	around	RP
cord-010027-r0tl01kq	1426	8	times	time	NNS
cord-010027-r0tl01kq	1426	9	and	and	CC
cord-010027-r0tl01kq	1426	10	improvement	improvement	NN
cord-010027-r0tl01kq	1426	11	strategies	strategy	NNS
cord-010027-r0tl01kq	1427	1	•	•	NNP
cord-010027-r0tl01kq	1428	1	Support	support	NN
cord-010027-r0tl01kq	1428	2	recruitment	recruitment	NN
cord-010027-r0tl01kq	1428	3	to	to	TO
cord-010027-r0tl01kq	1428	4	increase	increase	VB
cord-010027-r0tl01kq	1428	5	reporting	reporting	NN
cord-010027-r0tl01kq	1428	6	capacity	capacity	NN
cord-010027-r0tl01kq	1428	7	.	.	.
cord-010027-r0tl01kq	1429	1	•	•	NNP
cord-010027-r0tl01kq	1430	1	Maintain	maintain	VB
cord-010027-r0tl01kq	1430	2	awareness	awareness	NN
cord-010027-r0tl01kq	1430	3	of	of	IN
cord-010027-r0tl01kq	1430	4	the	the	DT
cord-010027-r0tl01kq	1430	5	need	need	NN
cord-010027-r0tl01kq	1430	6	to	to	TO
cord-010027-r0tl01kq	1430	7	recognise	recognise	VB
cord-010027-r0tl01kq	1430	8	serosal	serosal	NN
cord-010027-r0tl01kq	1430	9	involvement	involvement	NN
cord-010027-r0tl01kq	1430	10	in	in	IN
cord-010027-r0tl01kq	1430	11	rectal	rectal	JJ
cord-010027-r0tl01kq	1430	12	excisions	excision	NNS
cord-010027-r0tl01kq	1430	13	.	.	.
cord-010027-r0tl01kq	1431	1	•	•	NNP
cord-010027-r0tl01kq	1432	1	Re	Re	NNS
cord-010027-r0tl01kq	1432	2	-	-	NN
cord-010027-r0tl01kq	1432	3	audit	audit	NN
cord-010027-r0tl01kq	1432	4	in	in	IN
cord-010027-r0tl01kq	1432	5	1	1	CD
cord-010027-r0tl01kq	1432	6	year	year	NN
cord-010027-r0tl01kq	1432	7	.	.	.
cord-010027-r0tl01kq	1433	1	The	the	DT
cord-010027-r0tl01kq	1433	2	design	design	NN
cord-010027-r0tl01kq	1433	3	and	and	CC
cord-010027-r0tl01kq	1433	4	maintenance	maintenance	NN
cord-010027-r0tl01kq	1433	5	of	of	IN
cord-010027-r0tl01kq	1433	6	a	a	DT
cord-010027-r0tl01kq	1433	7	pilot	pilot	NN
cord-010027-r0tl01kq	1433	8	online	online	NN
cord-010027-r0tl01kq	1433	9	digital	digital	JJ
cord-010027-r0tl01kq	1433	10	archive	archive	NN
cord-010027-r0tl01kq	1433	11	of	of	IN
cord-010027-r0tl01kq	1433	12	archetype	archetype	NN
cord-010027-r0tl01kq	1433	13	colorectal	colorectal	JJ
cord-010027-r0tl01kq	1433	14	polyps	polyp	NNS
cord-010027-r0tl01kq	1433	15	and	and	CC
cord-010027-r0tl01kq	1433	16	gastrointestinal	gastrointestinal	JJ
cord-010027-r0tl01kq	1433	17	(	(	-LRB-
cord-010027-r0tl01kq	1433	18	GI	gi	NN
cord-010027-r0tl01kq	1433	19	)	)	-RRB-
cord-010027-r0tl01kq	1433	20	teaching	teaching	NN
cord-010027-r0tl01kq	1433	21	cases	case	NNS
cord-010027-r0tl01kq	1433	22	for	for	IN
cord-010027-r0tl01kq	1433	23	the	the	DT
cord-010027-r0tl01kq	1433	24	National	National	NNP
cord-010027-r0tl01kq	1433	25	Bowl	Bowl	NNP
cord-010027-r0tl01kq	1433	26	Screening	Screening	NNP
cord-010027-r0tl01kq	1433	27	programme	programme	NN
cord-010027-r0tl01kq	1433	28	(	(	-LRB-
cord-010027-r0tl01kq	1433	29	BowelScreen	BowelScreen	NNP
cord-010027-r0tl01kq	1433	30	)	)	-RRB-
cord-010027-r0tl01kq	1433	31	in	in	IN
cord-010027-r0tl01kq	1433	32	the	the	DT
cord-010027-r0tl01kq	1433	33	Republic	Republic	NNP
cord-010027-r0tl01kq	1433	34	of	of	IN
cord-010027-r0tl01kq	1433	35	Ireland	Ireland	NNP
cord-010027-r0tl01kq	1433	36	.	.	.
cord-010027-r0tl01kq	1434	1	Methods	method	NNS
cord-010027-r0tl01kq	1434	2	:	:	:
cord-010027-r0tl01kq	1435	1	Suitable	suitable	JJ
cord-010027-r0tl01kq	1435	2	internal	internal	JJ
cord-010027-r0tl01kq	1435	3	and	and	CC
cord-010027-r0tl01kq	1435	4	referral	referral	JJ
cord-010027-r0tl01kq	1435	5	cases	case	NNS
cord-010027-r0tl01kq	1435	6	were	be	VBD
cord-010027-r0tl01kq	1435	7	identified	identify	VBN
cord-010027-r0tl01kq	1435	8	by	by	IN
cord-010027-r0tl01kq	1435	9	BowelScreen	BowelScreen	NNP
cord-010027-r0tl01kq	1435	10	consultants	consultant	NNS
cord-010027-r0tl01kq	1435	11	at	at	IN
cord-010027-r0tl01kq	1435	12	Saint	Saint	NNP
cord-010027-r0tl01kq	1435	13	Vincent	Vincent	NNP
cord-010027-r0tl01kq	1435	14	's	's	POS
cord-010027-r0tl01kq	1435	15	University	University	NNP
cord-010027-r0tl01kq	1435	16	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1435	17	.	.	.
cord-010027-r0tl01kq	1436	1	These	these	DT
cord-010027-r0tl01kq	1436	2	cases	case	NNS
cord-010027-r0tl01kq	1436	3	were	be	VBD
cord-010027-r0tl01kq	1436	4	subject	subject	JJ
cord-010027-r0tl01kq	1436	5	to	to	IN
cord-010027-r0tl01kq	1436	6	both	both	CC
cord-010027-r0tl01kq	1436	7	internal	internal	JJ
cord-010027-r0tl01kq	1436	8	and	and	CC
cord-010027-r0tl01kq	1436	9	external	external	JJ
cord-010027-r0tl01kq	1436	10	review	review	NN
cord-010027-r0tl01kq	1436	11	,	,	,
cord-010027-r0tl01kq	1436	12	by	by	IN
cord-010027-r0tl01kq	1436	13	the	the	DT
cord-010027-r0tl01kq	1436	14	Mater	Mater	NNP
cord-010027-r0tl01kq	1436	15	Misericordiae	Misericordiae	NNP
cord-010027-r0tl01kq	1436	16	University	University	NNP
cord-010027-r0tl01kq	1436	17	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1436	18	,	,	,
cord-010027-r0tl01kq	1436	19	and	and	CC
cord-010027-r0tl01kq	1436	20	represented	represent	VBD
cord-010027-r0tl01kq	1436	21	typical	typical	JJ
cord-010027-r0tl01kq	1436	22	examples	example	NNS
cord-010027-r0tl01kq	1436	23	of	of	IN
cord-010027-r0tl01kq	1436	24	lesions	lesion	NNS
cord-010027-r0tl01kq	1436	25	seen	see	VBN
cord-010027-r0tl01kq	1436	26	in	in	IN
cord-010027-r0tl01kq	1436	27	a	a	DT
cord-010027-r0tl01kq	1436	28	National	National	NNP
cord-010027-r0tl01kq	1436	29	Bowel	Bowel	NNP
cord-010027-r0tl01kq	1436	30	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1436	31	screening	screening	NN
cord-010027-r0tl01kq	1436	32	programmes	programme	NNS
cord-010027-r0tl01kq	1436	33	(	(	-LRB-
cord-010027-r0tl01kq	1436	34	e.g	e.g	IN
cord-010027-r0tl01kq	1436	35	adenomas	adenoma	NNS
cord-010027-r0tl01kq	1436	36	,	,	,
cord-010027-r0tl01kq	1436	37	SSLs	ssl	NNS
cord-010027-r0tl01kq	1436	38	,	,	,
cord-010027-r0tl01kq	1436	39	adenomas	adenoma	NNS
cord-010027-r0tl01kq	1436	40	with	with	IN
cord-010027-r0tl01kq	1436	41	misplacement	misplacement	NN
cord-010027-r0tl01kq	1436	42	,	,	,
cord-010027-r0tl01kq	1436	43	TSAs	tsa	NNS
cord-010027-r0tl01kq	1436	44	)	)	-RRB-
cord-010027-r0tl01kq	1436	45	.	.	.
cord-010027-r0tl01kq	1437	1	Representative	representative	JJ
cord-010027-r0tl01kq	1437	2	slides	slide	NNS
cord-010027-r0tl01kq	1437	3	,	,	,
cord-010027-r0tl01kq	1437	4	including	include	VBG
cord-010027-r0tl01kq	1437	5	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1437	6	,	,	,
cord-010027-r0tl01kq	1437	7	were	be	VBD
cord-010027-r0tl01kq	1437	8	anonymised	anonymise	VBN
cord-010027-r0tl01kq	1437	9	and	and	CC
cord-010027-r0tl01kq	1437	10	digitised	digitise	VBN
cord-010027-r0tl01kq	1437	11	using	use	VBG
cord-010027-r0tl01kq	1437	12	the	the	DT
cord-010027-r0tl01kq	1437	13	Hamamatsu	Hamamatsu	NNP
cord-010027-r0tl01kq	1437	14	NanoZoomer	NanoZoomer	NNP
cord-010027-r0tl01kq	1437	15	Digital	Digital	NNP
cord-010027-r0tl01kq	1437	16	Pathology	Pathology	NNP
cord-010027-r0tl01kq	1437	17	(	(	-LRB-
cord-010027-r0tl01kq	1437	18	NDP	NDP	NNP
cord-010027-r0tl01kq	1437	19	)	)	-RRB-
cord-010027-r0tl01kq	1437	20	whole	whole	JJ
cord-010027-r0tl01kq	1437	21	slide	slide	NN
cord-010027-r0tl01kq	1437	22	scanner	scanner	NN
cord-010027-r0tl01kq	1437	23	platform	platform	NN
cord-010027-r0tl01kq	1437	24	and	and	CC
cord-010027-r0tl01kq	1437	25	associated	associated	JJ
cord-010027-r0tl01kq	1437	26	software	software	NN
cord-010027-r0tl01kq	1437	27	packages	package	NNS
cord-010027-r0tl01kq	1437	28	(	(	-LRB-
cord-010027-r0tl01kq	1437	29	NDP	NDP	NNP
cord-010027-r0tl01kq	1437	30	scan	scan	NN
cord-010027-r0tl01kq	1437	31	and	and	CC
cord-010027-r0tl01kq	1437	32	view	view	VBP
cord-010027-r0tl01kq	1437	33	)	)	-RRB-
cord-010027-r0tl01kq	1437	34	.	.	.
cord-010027-r0tl01kq	1438	1	Whole	whole	JJ
cord-010027-r0tl01kq	1438	2	slide	slide	NN
cord-010027-r0tl01kq	1438	3	images	image	NNS
cord-010027-r0tl01kq	1438	4	(	(	-LRB-
cord-010027-r0tl01kq	1438	5	WSI	WSI	NNP
cord-010027-r0tl01kq	1438	6	)	)	-RRB-
cord-010027-r0tl01kq	1438	7	were	be	VBD
cord-010027-r0tl01kq	1438	8	uploaded	upload	VBN
cord-010027-r0tl01kq	1438	9	to	to	TO
cord-010027-r0tl01kq	1438	10	secure	secure	VB
cord-010027-r0tl01kq	1438	11	cloud	cloud	NN
cord-010027-r0tl01kq	1438	12	storage	storage	NN
cord-010027-r0tl01kq	1438	13	using	use	VBG
cord-010027-r0tl01kq	1438	14	a	a	DT
cord-010027-r0tl01kq	1438	15	generic	generic	JJ
cord-010027-r0tl01kq	1438	16	file	file	NN
cord-010027-r0tl01kq	1438	17	transfer	transfer	NN
cord-010027-r0tl01kq	1438	18	protocol	protocol	NN
cord-010027-r0tl01kq	1438	19	program	program	NN
cord-010027-r0tl01kq	1438	20	.	.	.
cord-010027-r0tl01kq	1439	1	WSI	WSI	NNP
cord-010027-r0tl01kq	1439	2	were	be	VBD
cord-010027-r0tl01kq	1439	3	collated	collate	VBN
cord-010027-r0tl01kq	1439	4	into	into	IN
cord-010027-r0tl01kq	1439	5	18	18	CD
cord-010027-r0tl01kq	1439	6	cases	case	NNS
cord-010027-r0tl01kq	1439	7	and	and	CC
cord-010027-r0tl01kq	1439	8	accessible	accessible	JJ
cord-010027-r0tl01kq	1439	9	via	via	IN
cord-010027-r0tl01kq	1439	10	the	the	DT
cord-010027-r0tl01kq	1439	11	PathXL	PathXL	NNP
cord-010027-r0tl01kq	1439	12	gateway	gateway	NN
cord-010027-r0tl01kq	1439	13	(	(	-LRB-
cord-010027-r0tl01kq	1439	14	pathXL.co.uk	pathXL.co.uk	NNP
cord-010027-r0tl01kq	1439	15	)	)	-RRB-
cord-010027-r0tl01kq	1439	16	by	by	IN
cord-010027-r0tl01kq	1439	17	approved	approve	VBN
cord-010027-r0tl01kq	1439	18	users	user	NNS
cord-010027-r0tl01kq	1439	19	via	via	IN
cord-010027-r0tl01kq	1439	20	an	an	DT
cord-010027-r0tl01kq	1439	21	online	online	JJ
cord-010027-r0tl01kq	1439	22	case	case	NN
cord-010027-r0tl01kq	1439	23	referral	referral	NN
cord-010027-r0tl01kq	1439	24	and	and	CC
cord-010027-r0tl01kq	1439	25	reporting	reporting	NN
cord-010027-r0tl01kq	1439	26	system	system	NN
cord-010027-r0tl01kq	1439	27	.	.	.
cord-010027-r0tl01kq	1440	1	Users	user	NNS
cord-010027-r0tl01kq	1440	2	were	be	VBD
cord-010027-r0tl01kq	1440	3	notified	notify	VBN
cord-010027-r0tl01kq	1440	4	of	of	IN
cord-010027-r0tl01kq	1440	5	pending	pende	VBG
cord-010027-r0tl01kq	1440	6	cases	case	NNS
cord-010027-r0tl01kq	1440	7	via	via	IN
cord-010027-r0tl01kq	1440	8	email	email	NN
cord-010027-r0tl01kq	1440	9	and	and	CC
cord-010027-r0tl01kq	1440	10	the	the	DT
cord-010027-r0tl01kq	1440	11	viewing	viewing	NN
cord-010027-r0tl01kq	1440	12	of	of	IN
cord-010027-r0tl01kq	1440	13	WSI	WSI	NNP
cord-010027-r0tl01kq	1440	14	occurred	occur	VBD
cord-010027-r0tl01kq	1440	15	within	within	IN
cord-010027-r0tl01kq	1440	16	the	the	DT
cord-010027-r0tl01kq	1440	17	user	user	NN
cord-010027-r0tl01kq	1440	18	's	's	POS
cord-010027-r0tl01kq	1440	19	web	web	NN
cord-010027-r0tl01kq	1440	20	browser	browser	NN
cord-010027-r0tl01kq	1440	21	utilising	utilise	VBG
cord-010027-r0tl01kq	1440	22	an	an	DT
cord-010027-r0tl01kq	1440	23	online	online	JJ
cord-010027-r0tl01kq	1440	24	version	version	NN
cord-010027-r0tl01kq	1440	25	of	of	IN
cord-010027-r0tl01kq	1440	26	NDP	NDP	NNP
cord-010027-r0tl01kq	1440	27	view	view	NN
cord-010027-r0tl01kq	1440	28	program	program	NN
cord-010027-r0tl01kq	1440	29	and	and	CC
cord-010027-r0tl01kq	1440	30	did	do	VBD
cord-010027-r0tl01kq	1440	31	not	not	RB
cord-010027-r0tl01kq	1440	32	require	require	VB
cord-010027-r0tl01kq	1440	33	local	local	JJ
cord-010027-r0tl01kq	1440	34	use	use	NN
cord-010027-r0tl01kq	1440	35	of	of	IN
cord-010027-r0tl01kq	1440	36	propriety	propriety	NN
cord-010027-r0tl01kq	1440	37	software	software	NN
cord-010027-r0tl01kq	1440	38	.	.	.
cord-010027-r0tl01kq	1441	1	Each	each	DT
cord-010027-r0tl01kq	1441	2	case	case	NN
cord-010027-r0tl01kq	1441	3	was	be	VBD
cord-010027-r0tl01kq	1441	4	referred	refer	VBN
cord-010027-r0tl01kq	1441	5	across	across	IN
cord-010027-r0tl01kq	1441	6	the	the	DT
cord-010027-r0tl01kq	1441	7	two	two	CD
cord-010027-r0tl01kq	1441	8	participating	participate	VBG
cord-010027-r0tl01kq	1441	9	sites	site	NNS
cord-010027-r0tl01kq	1441	10	and	and	CC
cord-010027-r0tl01kq	1441	11	scored	score	VBD
cord-010027-r0tl01kq	1441	12	in	in	IN
cord-010027-r0tl01kq	1441	13	four	four	CD
cord-010027-r0tl01kq	1441	14	areas	area	NNS
cord-010027-r0tl01kq	1441	15	;	;	:
cord-010027-r0tl01kq	1441	16	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1441	17	concordance	concordance	NN
cord-010027-r0tl01kq	1441	18	,	,	,
cord-010027-r0tl01kq	1441	19	quality	quality	NN
cord-010027-r0tl01kq	1441	20	of	of	IN
cord-010027-r0tl01kq	1441	21	WSI	WSI	NNP
cord-010027-r0tl01kq	1441	22	,	,	,
cord-010027-r0tl01kq	1441	23	web	web	NN
cord-010027-r0tl01kq	1441	24	interface	interface	NN
cord-010027-r0tl01kq	1441	25	and	and	CC
cord-010027-r0tl01kq	1441	26	the	the	DT
cord-010027-r0tl01kq	1441	27	online	online	JJ
cord-010027-r0tl01kq	1441	28	referral	referral	NN
cord-010027-r0tl01kq	1441	29	and	and	CC
cord-010027-r0tl01kq	1441	30	reporting	reporting	NN
cord-010027-r0tl01kq	1441	31	system	system	NN
cord-010027-r0tl01kq	1441	32	.	.	.
cord-010027-r0tl01kq	1442	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1442	2	:	:	:
cord-010027-r0tl01kq	1442	3	With	with	IN
cord-010027-r0tl01kq	1442	4	the	the	DT
cord-010027-r0tl01kq	1442	5	maturation	maturation	NN
cord-010027-r0tl01kq	1442	6	of	of	IN
cord-010027-r0tl01kq	1442	7	technology	technology	NN
cord-010027-r0tl01kq	1442	8	involved	involve	VBN
cord-010027-r0tl01kq	1442	9	in	in	IN
cord-010027-r0tl01kq	1442	10	digital	digital	JJ
cord-010027-r0tl01kq	1442	11	microscopy	microscopy	NNP
cord-010027-r0tl01kq	1442	12	a	a	DT
cord-010027-r0tl01kq	1442	13	digital	digital	JJ
cord-010027-r0tl01kq	1442	14	archive	archive	NN
cord-010027-r0tl01kq	1442	15	program	program	NN
cord-010027-r0tl01kq	1442	16	is	be	VBZ
cord-010027-r0tl01kq	1442	17	now	now	RB
cord-010027-r0tl01kq	1442	18	a	a	DT
cord-010027-r0tl01kq	1442	19	feasible	feasible	JJ
cord-010027-r0tl01kq	1442	20	approach	approach	NN
cord-010027-r0tl01kq	1442	21	to	to	IN
cord-010027-r0tl01kq	1442	22	the	the	DT
cord-010027-r0tl01kq	1442	23	standardisation	standardisation	NN
cord-010027-r0tl01kq	1442	24	of	of	IN
cord-010027-r0tl01kq	1442	25	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1442	26	and	and	CC
cord-010027-r0tl01kq	1442	27	a	a	DT
cord-010027-r0tl01kq	1442	28	useful	useful	JJ
cord-010027-r0tl01kq	1442	29	adjunct	adjunct	NN
cord-010027-r0tl01kq	1442	30	to	to	IN
cord-010027-r0tl01kq	1442	31	traditional	traditional	JJ
cord-010027-r0tl01kq	1442	32	optical	optical	JJ
cord-010027-r0tl01kq	1442	33	microscopy	microscopy	NN
cord-010027-r0tl01kq	1442	34	in	in	IN
cord-010027-r0tl01kq	1442	35	education	education	NN
cord-010027-r0tl01kq	1442	36	within	within	IN
cord-010027-r0tl01kq	1442	37	the	the	DT
cord-010027-r0tl01kq	1442	38	National	National	NNP
cord-010027-r0tl01kq	1442	39	Bowel	Bowel	NNP
cord-010027-r0tl01kq	1442	40	Screening	Screening	NNP
cord-010027-r0tl01kq	1442	41	programme	programme	NN
cord-010027-r0tl01kq	1442	42	.	.	.
cord-010027-r0tl01kq	1443	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1443	2	:	:	:
cord-010027-r0tl01kq	1444	1	A	a	DT
cord-010027-r0tl01kq	1444	2	committed	committed	JJ
cord-010027-r0tl01kq	1444	3	and	and	CC
cord-010027-r0tl01kq	1444	4	conscientious	conscientious	JJ
cord-010027-r0tl01kq	1444	5	BMS	BMS	NNP
cord-010027-r0tl01kq	1444	6	can	can	MD
cord-010027-r0tl01kq	1444	7	learn	learn	VB
cord-010027-r0tl01kq	1444	8	how	how	WRB
cord-010027-r0tl01kq	1444	9	to	to	TO
cord-010027-r0tl01kq	1444	10	report	report	VB
cord-010027-r0tl01kq	1444	11	histopathology	histopathology	NN
cord-010027-r0tl01kq	1444	12	cases	case	NNS
cord-010027-r0tl01kq	1444	13	.	.	.
cord-010027-r0tl01kq	1445	1	However	however	RB
cord-010027-r0tl01kq	1445	2	,	,	,
cord-010027-r0tl01kq	1445	3	if	if	IN
cord-010027-r0tl01kq	1445	4	this	this	DT
cord-010027-r0tl01kq	1445	5	is	be	VBZ
cord-010027-r0tl01kq	1445	6	to	to	TO
cord-010027-r0tl01kq	1445	7	be	be	VB
cord-010027-r0tl01kq	1445	8	achieved	achieve	VBN
cord-010027-r0tl01kq	1445	9	,	,	,
cord-010027-r0tl01kq	1445	10	the	the	DT
cord-010027-r0tl01kq	1445	11	department	department	NN
cord-010027-r0tl01kq	1445	12	in	in	IN
cord-010027-r0tl01kq	1445	13	which	which	WDT
cord-010027-r0tl01kq	1445	14	he	-PRON-	PRP
cord-010027-r0tl01kq	1445	15	or	or	CC
cord-010027-r0tl01kq	1445	16	she	-PRON-	PRP
cord-010027-r0tl01kq	1445	17	works	work	VBZ
cord-010027-r0tl01kq	1445	18	must	must	MD
cord-010027-r0tl01kq	1445	19	also	also	RB
cord-010027-r0tl01kq	1445	20	be	be	VB
cord-010027-r0tl01kq	1445	21	committed	commit	VBN
cord-010027-r0tl01kq	1445	22	and	and	CC
cord-010027-r0tl01kq	1445	23	supportive	supportive	JJ
cord-010027-r0tl01kq	1445	24	.	.	.
cord-010027-r0tl01kq	1446	1	Carcinoid	Carcinoid	NNP
cord-010027-r0tl01kq	1446	2	Tumour	tumour	NN
cord-010027-r0tl01kq	1446	3	of	of	IN
cord-010027-r0tl01kq	1446	4	the	the	DT
cord-010027-r0tl01kq	1446	5	Appendix	Appendix	NNP
cord-010027-r0tl01kq	1446	6	:	:	:
cord-010027-r0tl01kq	1447	1	A	a	DT
cord-010027-r0tl01kq	1447	2	Case	Case	NNP
cord-010027-r0tl01kq	1447	3	Report	report	NN
cord-010027-r0tl01kq	1447	4	P	P	NNP
cord-010027-r0tl01kq	1447	5	AAE	AAE	NNP
cord-010027-r0tl01kq	1447	6	Shalaby	Shalaby	NNPS
cord-010027-r0tl01kq	1447	7	;	;	:
cord-010027-r0tl01kq	1447	8	P	P	NNP
cord-010027-r0tl01kq	1447	9	AAE	AAE	NNP
cord-010027-r0tl01kq	1447	10	Shalaby	Shalaby	NNP
cord-010027-r0tl01kq	1447	11	A	a	DT
cord-010027-r0tl01kq	1447	12	case	case	NN
cord-010027-r0tl01kq	1447	13	of	of	IN
cord-010027-r0tl01kq	1447	14	a	a	DT
cord-010027-r0tl01kq	1447	15	24	24	CD
cord-010027-r0tl01kq	1447	16	years	year	NNS
cord-010027-r0tl01kq	1447	17	male	male	NN
cord-010027-r0tl01kq	1447	18	operated	operate	VBD
cord-010027-r0tl01kq	1447	19	on	on	IN
cord-010027-r0tl01kq	1447	20	for	for	IN
cord-010027-r0tl01kq	1447	21	acute	acute	JJ
cord-010027-r0tl01kq	1447	22	appendicitis	appendicitis	NN
cord-010027-r0tl01kq	1447	23	and	and	CC
cord-010027-r0tl01kq	1447	24	an	an	DT
cord-010027-r0tl01kq	1447	25	incidental	incidental	JJ
cord-010027-r0tl01kq	1447	26	finding	finding	NN
cord-010027-r0tl01kq	1447	27	of	of	IN
cord-010027-r0tl01kq	1447	28	a	a	DT
cord-010027-r0tl01kq	1447	29	carcinoid	carcinoid	NN
cord-010027-r0tl01kq	1447	30	tumour	tumour	NN
cord-010027-r0tl01kq	1447	31	at	at	IN
cord-010027-r0tl01kq	1447	32	the	the	DT
cord-010027-r0tl01kq	1447	33	tip	tip	NN
cord-010027-r0tl01kq	1447	34	is	be	VBZ
cord-010027-r0tl01kq	1447	35	reported	report	VBN
cord-010027-r0tl01kq	1447	36	.	.	.
cord-010027-r0tl01kq	1448	1	The	the	DT
cord-010027-r0tl01kq	1448	2	tumour	tumour	NN
cord-010027-r0tl01kq	1448	3	was	be	VBD
cord-010027-r0tl01kq	1448	4	less	less	JJR
cord-010027-r0tl01kq	1448	5	than	than	IN
cord-010027-r0tl01kq	1448	6	2	2	CD
cord-010027-r0tl01kq	1448	7	cm	cm	NNS
cord-010027-r0tl01kq	1448	8	in	in	IN
cord-010027-r0tl01kq	1448	9	greatest	great	JJS
cord-010027-r0tl01kq	1448	10	dimension	dimension	NN
cord-010027-r0tl01kq	1449	1	but	but	CC
cord-010027-r0tl01kq	1449	2	it	-PRON-	PRP
cord-010027-r0tl01kq	1449	3	infiltrates	infiltrate	VBZ
cord-010027-r0tl01kq	1449	4	through	through	IN
cord-010027-r0tl01kq	1449	5	the	the	DT
cord-010027-r0tl01kq	1449	6	wall	wall	NN
cord-010027-r0tl01kq	1449	7	of	of	IN
cord-010027-r0tl01kq	1449	8	the	the	DT
cord-010027-r0tl01kq	1449	9	appendix	appendix	NN
cord-010027-r0tl01kq	1449	10	into	into	IN
cord-010027-r0tl01kq	1449	11	the	the	DT
cord-010027-r0tl01kq	1449	12	surrounding	surround	VBG
cord-010027-r0tl01kq	1449	13	fat	fat	NN
cord-010027-r0tl01kq	1449	14	.	.	.
cord-010027-r0tl01kq	1450	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1450	2	stains	stain	VBZ
cord-010027-r0tl01kq	1450	3	positive	positive	JJ
cord-010027-r0tl01kq	1450	4	for	for	IN
cord-010027-r0tl01kq	1450	5	the	the	DT
cord-010027-r0tl01kq	1450	6	neuroendocrine	neuroendocrine	JJ
cord-010027-r0tl01kq	1450	7	markers	marker	NNS
cord-010027-r0tl01kq	1450	8	.	.	.
cord-010027-r0tl01kq	1451	1	Carcinoid	carcinoid	NN
cord-010027-r0tl01kq	1451	2	tumour	tumour	NN
cord-010027-r0tl01kq	1451	3	of	of	IN
cord-010027-r0tl01kq	1451	4	the	the	DT
cord-010027-r0tl01kq	1451	5	appendix	appendix	NN
cord-010027-r0tl01kq	1451	6	is	be	VBZ
cord-010027-r0tl01kq	1451	7	unusual	unusual	JJ
cord-010027-r0tl01kq	1451	8	,	,	,
cord-010027-r0tl01kq	1451	9	but	but	CC
cord-010027-r0tl01kq	1451	10	it	-PRON-	PRP
cord-010027-r0tl01kq	1451	11	has	have	VBZ
cord-010027-r0tl01kq	1451	12	to	to	TO
cord-010027-r0tl01kq	1451	13	be	be	VB
cord-010027-r0tl01kq	1451	14	looked	look	VBN
cord-010027-r0tl01kq	1451	15	for	for	IN
cord-010027-r0tl01kq	1451	16	during	during	IN
cord-010027-r0tl01kq	1451	17	examination	examination	NN
cord-010027-r0tl01kq	1451	18	of	of	IN
cord-010027-r0tl01kq	1451	19	appendectomy	appendectomy	NN
cord-010027-r0tl01kq	1451	20	specimens	specimen	NNS
cord-010027-r0tl01kq	1451	21	done	do	VBN
cord-010027-r0tl01kq	1451	22	for	for	IN
cord-010027-r0tl01kq	1451	23	appendicitis	appendicitis	NN
cord-010027-r0tl01kq	1451	24	(	(	-LRB-
cord-010027-r0tl01kq	1451	25	0.5	0.5	CD
cord-010027-r0tl01kq	1451	26	%	%	NN
cord-010027-r0tl01kq	1451	27	)	)	-RRB-
cord-010027-r0tl01kq	1451	28	.	.	.
cord-010027-r0tl01kq	1452	1	Women	woman	NNS
cord-010027-r0tl01kq	1452	2	are	be	VBP
cord-010027-r0tl01kq	1452	3	more	more	RBR
cord-010027-r0tl01kq	1452	4	frequently	frequently	RB
cord-010027-r0tl01kq	1452	5	affected	affect	VBN
cord-010027-r0tl01kq	1452	6	than	than	IN
cord-010027-r0tl01kq	1452	7	men	man	NNS
cord-010027-r0tl01kq	1452	8	(	(	-LRB-
cord-010027-r0tl01kq	1452	9	3:1	3:1	CD
cord-010027-r0tl01kq	1452	10	)	)	-RRB-
cord-010027-r0tl01kq	1452	11	and	and	CC
cord-010027-r0tl01kq	1452	12	the	the	DT
cord-010027-r0tl01kq	1452	13	tumour	tumour	NN
cord-010027-r0tl01kq	1452	14	is	be	VBZ
cord-010027-r0tl01kq	1452	15	usually	usually	RB
cord-010027-r0tl01kq	1452	16	small	small	JJ
cord-010027-r0tl01kq	1452	17	less	less	JJR
cord-010027-r0tl01kq	1452	18	than	than	IN
cord-010027-r0tl01kq	1452	19	1	1	CD
cord-010027-r0tl01kq	1452	20	cm	cm	NNS
cord-010027-r0tl01kq	1452	21	in	in	IN
cord-010027-r0tl01kq	1452	22	diameter	diameter	NN
cord-010027-r0tl01kq	1452	23	and	and	CC
cord-010027-r0tl01kq	1452	24	frequently	frequently	RB
cord-010027-r0tl01kq	1452	25	located	locate	VBN
cord-010027-r0tl01kq	1452	26	at	at	IN
cord-010027-r0tl01kq	1452	27	the	the	DT
cord-010027-r0tl01kq	1452	28	tip	tip	NN
cord-010027-r0tl01kq	1452	29	.	.	.
cord-010027-r0tl01kq	1453	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1453	2	is	be	VBZ
cord-010027-r0tl01kq	1453	3	usually	usually	RB
cord-010027-r0tl01kq	1453	4	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1453	5	incidentally	incidentally	RB
cord-010027-r0tl01kq	1453	6	after	after	IN
cord-010027-r0tl01kq	1453	7	an	an	DT
cord-010027-r0tl01kq	1453	8	operation	operation	NN
cord-010027-r0tl01kq	1453	9	for	for	IN
cord-010027-r0tl01kq	1453	10	acute	acute	JJ
cord-010027-r0tl01kq	1453	11	appendicitis	appendicitis	NN
cord-010027-r0tl01kq	1453	12	and	and	CC
cord-010027-r0tl01kq	1453	13	sometimes	sometimes	RB
cord-010027-r0tl01kq	1453	14	during	during	IN
cord-010027-r0tl01kq	1453	15	other	other	JJ
cord-010027-r0tl01kq	1453	16	procedures	procedure	NNS
cord-010027-r0tl01kq	1453	17	(	(	-LRB-
cord-010027-r0tl01kq	1453	18	colectomy	colectomy	JJ
cord-010027-r0tl01kq	1453	19	,	,	,
cord-010027-r0tl01kq	1453	20	cholecystectomy	cholecystectomy	NN
cord-010027-r0tl01kq	1453	21	and	and	CC
cord-010027-r0tl01kq	1453	22	others	other	NNS
cord-010027-r0tl01kq	1453	23	)	)	-RRB-
cord-010027-r0tl01kq	1453	24	.	.	.
cord-010027-r0tl01kq	1454	1	The	the	DT
cord-010027-r0tl01kq	1454	2	tumour	tumour	NN
cord-010027-r0tl01kq	1454	3	rarely	rarely	RB
cord-010027-r0tl01kq	1454	4	metastasis	metastasis	NN
cord-010027-r0tl01kq	1454	5	to	to	IN
cord-010027-r0tl01kq	1454	6	the	the	DT
cord-010027-r0tl01kq	1454	7	liver	liver	NN
cord-010027-r0tl01kq	1454	8	and	and	CC
cord-010027-r0tl01kq	1454	9	this	this	DT
cord-010027-r0tl01kq	1454	10	is	be	VBZ
cord-010027-r0tl01kq	1454	11	usually	usually	RB
cord-010027-r0tl01kq	1454	12	related	relate	VBN
cord-010027-r0tl01kq	1454	13	to	to	IN
cord-010027-r0tl01kq	1454	14	the	the	DT
cord-010027-r0tl01kq	1454	15	tumour	tumour	NN
cord-010027-r0tl01kq	1454	16	diameter	diameter	NN
cord-010027-r0tl01kq	1454	17	)	)	-RRB-
cord-010027-r0tl01kq	1454	18	and	and	CC
cord-010027-r0tl01kq	1454	19	can	can	MD
cord-010027-r0tl01kq	1454	20	cause	cause	VB
cord-010027-r0tl01kq	1454	21	a	a	DT
cord-010027-r0tl01kq	1454	22	"	"	``
cord-010027-r0tl01kq	1454	23	carcinoid	carcinoid	NN
cord-010027-r0tl01kq	1454	24	syndrome	syndrome	NN
cord-010027-r0tl01kq	1454	25	"	"	''
cord-010027-r0tl01kq	1454	26	:	:	:
cord-010027-r0tl01kq	1454	27	flush	flush	VB
cord-010027-r0tl01kq	1454	28	,	,	,
cord-010027-r0tl01kq	1454	29	diarrhea	diarrhea	NN
cord-010027-r0tl01kq	1454	30	bronchoconstriction	bronchoconstriction	NN
cord-010027-r0tl01kq	1454	31	,	,	,
cord-010027-r0tl01kq	1454	32	cardiac	cardiac	JJ
cord-010027-r0tl01kq	1454	33	valve	valve	NN
cord-010027-r0tl01kq	1454	34	disease	disease	NN
cord-010027-r0tl01kq	1454	35	.	.	.
cord-010027-r0tl01kq	1455	1	Diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1455	2	is	be	VBZ
cord-010027-r0tl01kq	1455	3	made	make	VBN
cord-010027-r0tl01kq	1455	4	by	by	IN
cord-010027-r0tl01kq	1455	5	the	the	DT
cord-010027-r0tl01kq	1455	6	pathologist	pathologist	NN
cord-010027-r0tl01kq	1455	7	and	and	CC
cord-010027-r0tl01kq	1455	8	staging	staging	NN
cord-010027-r0tl01kq	1455	9	by	by	IN
cord-010027-r0tl01kq	1455	10	conventional	conventional	JJ
cord-010027-r0tl01kq	1455	11	radiologic	radiologic	JJ
cord-010027-r0tl01kq	1455	12	procedures	procedure	NNS
cord-010027-r0tl01kq	1455	13	(	(	-LRB-
cord-010027-r0tl01kq	1455	14	TAC	TAC	NNP
cord-010027-r0tl01kq	1455	15	,	,	,
cord-010027-r0tl01kq	1455	16	US	US	NNP
cord-010027-r0tl01kq	1455	17	)	)	-RRB-
cord-010027-r0tl01kq	1455	18	,	,	,
cord-010027-r0tl01kq	1455	19	dosage	dosage	NN
cord-010027-r0tl01kq	1455	20	of	of	IN
cord-010027-r0tl01kq	1455	21	neuroendocrine	neuroendocrine	JJ
cord-010027-r0tl01kq	1455	22	mediators	mediator	NNS
cord-010027-r0tl01kq	1455	23	such	such	JJ
cord-010027-r0tl01kq	1455	24	as	as	IN
cord-010027-r0tl01kq	1455	25	24	24	CD
cord-010027-r0tl01kq	1455	26	hours	hour	NNS
cord-010027-r0tl01kq	1455	27	urinary	urinary	JJ
cord-010027-r0tl01kq	1455	28	5-HIAA	5-hiaa	CD
cord-010027-r0tl01kq	1455	29	.	.	.
cord-010027-r0tl01kq	1456	1	Simple	simple	JJ
cord-010027-r0tl01kq	1456	2	appendectomy	appendectomy	NN
cord-010027-r0tl01kq	1456	3	is	be	VBZ
cord-010027-r0tl01kq	1456	4	adequate	adequate	JJ
cord-010027-r0tl01kq	1456	5	treatment	treatment	NN
cord-010027-r0tl01kq	1456	6	for	for	IN
cord-010027-r0tl01kq	1456	7	appendicular	appendicular	NNP
cord-010027-r0tl01kq	1456	8	carcinoids	carcinoids	NNP
cord-010027-r0tl01kq	1456	9	less	less	JJR
cord-010027-r0tl01kq	1456	10	than	than	IN
cord-010027-r0tl01kq	1456	11	1	1	CD
cord-010027-r0tl01kq	1456	12	cm	cm	NNS
cord-010027-r0tl01kq	1456	13	in	in	IN
cord-010027-r0tl01kq	1456	14	diameter	diameter	NN
cord-010027-r0tl01kq	1456	15	.	.	.
cord-010027-r0tl01kq	1457	1	Adequate	adequate	JJ
cord-010027-r0tl01kq	1457	2	treatment	treatment	NN
cord-010027-r0tl01kq	1457	3	for	for	IN
cord-010027-r0tl01kq	1457	4	tumours	tumour	NNS
cord-010027-r0tl01kq	1458	1	greater	great	JJR
cord-010027-r0tl01kq	1458	2	than	than	IN
cord-010027-r0tl01kq	1458	3	2	2	CD
cord-010027-r0tl01kq	1458	4	cm	cm	NN
cord-010027-r0tl01kq	1458	5	is	be	VBZ
cord-010027-r0tl01kq	1458	6	right	right	JJ
cord-010027-r0tl01kq	1458	7	hemicolectomy	hemicolectomy	NN
cord-010027-r0tl01kq	1458	8	.	.	.
cord-010027-r0tl01kq	1459	1	The	the	DT
cord-010027-r0tl01kq	1459	2	mangement	mangement	NN
cord-010027-r0tl01kq	1459	3	of	of	IN
cord-010027-r0tl01kq	1459	4	tumours	tumour	NNS
cord-010027-r0tl01kq	1459	5	1	1	CD
cord-010027-r0tl01kq	1459	6	to	to	IN
cord-010027-r0tl01kq	1459	7	2	2	CD
cord-010027-r0tl01kq	1459	8	cm	cm	NN
cord-010027-r0tl01kq	1459	9	range	range	NN
cord-010027-r0tl01kq	1459	10	is	be	VBZ
cord-010027-r0tl01kq	1459	11	controverisal	controverisal	VBN
cord-010027-r0tl01kq	1459	12	,	,	,
cord-010027-r0tl01kq	1459	13	but	but	CC
cord-010027-r0tl01kq	1459	14	generally	generally	RB
cord-010027-r0tl01kq	1459	15	,	,	,
cord-010027-r0tl01kq	1459	16	appendectomy	appendectomy	NN
cord-010027-r0tl01kq	1459	17	alone	alone	RB
cord-010027-r0tl01kq	1459	18	is	be	VBZ
cord-010027-r0tl01kq	1459	19	sufficient	sufficient	JJ
cord-010027-r0tl01kq	1459	20	except	except	IN
cord-010027-r0tl01kq	1459	21	when	when	WRB
cord-010027-r0tl01kq	1459	22	meso	meso	NN
cord-010027-r0tl01kq	1459	23	-	-	HYPH
cord-010027-r0tl01kq	1459	24	appendix	appendix	NNP
cord-010027-r0tl01kq	1459	25	is	be	VBZ
cord-010027-r0tl01kq	1459	26	invaded	invade	VBN
cord-010027-r0tl01kq	1459	27	.	.	.
cord-010027-r0tl01kq	1460	1	Carcinoid	carcinoid	NN
cord-010027-r0tl01kq	1460	2	tumour	tumour	NN
cord-010027-r0tl01kq	1460	3	of	of	IN
cord-010027-r0tl01kq	1460	4	the	the	DT
cord-010027-r0tl01kq	1460	5	appendix	appendix	NN
cord-010027-r0tl01kq	1460	6	has	have	VBZ
cord-010027-r0tl01kq	1460	7	a	a	DT
cord-010027-r0tl01kq	1460	8	good	good	JJ
cord-010027-r0tl01kq	1460	9	prognosis	prognosis	NN
cord-010027-r0tl01kq	1460	10	with	with	IN
cord-010027-r0tl01kq	1460	11	a	a	DT
cord-010027-r0tl01kq	1460	12	5-year	5-year	CD
cord-010027-r0tl01kq	1460	13	-	-	HYPH
cord-010027-r0tl01kq	1460	14	survival	survival	NN
cord-010027-r0tl01kq	1460	15	rate	rate	NN
cord-010027-r0tl01kq	1460	16	,	,	,
cord-010027-r0tl01kq	1460	17	of	of	IN
cord-010027-r0tl01kq	1460	18	85	85	CD
cord-010027-r0tl01kq	1460	19	-	-	SYM
cord-010027-r0tl01kq	1460	20	100	100	CD
cord-010027-r0tl01kq	1460	21	%	%	NN
cord-010027-r0tl01kq	1460	22	.	.	.
cord-010027-r0tl01kq	1461	1	The	the	DT
cord-010027-r0tl01kq	1461	2	Prevalence	prevalence	NN
cord-010027-r0tl01kq	1461	3	of	of	IN
cord-010027-r0tl01kq	1461	4	Epithelial	epithelial	JJ
cord-010027-r0tl01kq	1461	5	Changes	change	NNS
cord-010027-r0tl01kq	1461	6	in	in	IN
cord-010027-r0tl01kq	1461	7	Helicobacter	Helicobacter	NNP
cord-010027-r0tl01kq	1461	8	Pylori	Pylori	NNP
cord-010027-r0tl01kq	1461	9	-	-	HYPH
cord-010027-r0tl01kq	1461	10	Associated	Associated	NNP
cord-010027-r0tl01kq	1461	11	Gastritis	Gastritis	NNP
cord-010027-r0tl01kq	1461	12	in	in	IN
cord-010027-r0tl01kq	1461	13	Oman	Oman	NNP
cord-010027-r0tl01kq	1461	14	:	:	:
cord-010027-r0tl01kq	1462	1	A	a	DT
cord-010027-r0tl01kq	1462	2	Retrospective	Retrospective	NNP
cord-010027-r0tl01kq	1462	3	Study	Study	NNP
cord-010027-r0tl01kq	1462	4	P	P	NNP
cord-010027-r0tl01kq	1462	5	AAE	AAE	NNP
cord-010027-r0tl01kq	1462	6	Shalaby	Shalaby	NNPS
cord-010027-r0tl01kq	1462	7	;	;	:
cord-010027-r0tl01kq	1462	8	A	a	DT
cord-010027-r0tl01kq	1462	9	Al	Al	NNP
cord-010027-r0tl01kq	1462	10	Saadi	Saadi	NNP
cord-010027-r0tl01kq	1463	1	There	there	EX
cord-010027-r0tl01kq	1463	2	is	be	VBZ
cord-010027-r0tl01kq	1463	3	Strong	strong	JJ
cord-010027-r0tl01kq	1463	4	association	association	NN
cord-010027-r0tl01kq	1463	5	between	between	IN
cord-010027-r0tl01kq	1463	6	H.	H.	NNP
cord-010027-r0tl01kq	1463	7	pylori	pylori	VB
cord-010027-r0tl01kq	1463	8	gastric	gastric	JJ
cord-010027-r0tl01kq	1463	9	infection	infection	NN
cord-010027-r0tl01kq	1463	10	and	and	CC
cord-010027-r0tl01kq	1463	11	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1463	12	changes	change	NNS
cord-010027-r0tl01kq	1463	13	and	and	CC
cord-010027-r0tl01kq	1463	14	progression	progression	NN
cord-010027-r0tl01kq	1463	15	to	to	IN
cord-010027-r0tl01kq	1463	16	cancer	cancer	NN
cord-010027-r0tl01kq	1463	17	.	.	.
cord-010027-r0tl01kq	1464	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1464	2	has	have	VBZ
cord-010027-r0tl01kq	1464	3	been	be	VBN
cord-010027-r0tl01kq	1464	4	shown	show	VBN
cord-010027-r0tl01kq	1464	5	that	that	IN
cord-010027-r0tl01kq	1464	6	H	h	NN
cord-010027-r0tl01kq	1464	7	pylori	pylori	NN
cord-010027-r0tl01kq	1464	8	infection	infection	NN
cord-010027-r0tl01kq	1464	9	is	be	VBZ
cord-010027-r0tl01kq	1464	10	strongly	strongly	RB
cord-010027-r0tl01kq	1464	11	associated	associate	VBN
cord-010027-r0tl01kq	1464	12	with	with	IN
cord-010027-r0tl01kq	1464	13	high	high	JJ
cord-010027-r0tl01kq	1464	14	proliferative	proliferative	JJ
cord-010027-r0tl01kq	1464	15	activity	activity	NN
cord-010027-r0tl01kq	1464	16	and	and	CC
cord-010027-r0tl01kq	1464	17	it	-PRON-	PRP
cord-010027-r0tl01kq	1464	18	could	could	MD
cord-010027-r0tl01kq	1464	19	be	be	VB
cord-010027-r0tl01kq	1464	20	a	a	DT
cord-010027-r0tl01kq	1464	21	risk	risk	NN
cord-010027-r0tl01kq	1464	22	of	of	IN
cord-010027-r0tl01kq	1464	23	initial	initial	JJ
cord-010027-r0tl01kq	1464	24	step	step	NN
cord-010027-r0tl01kq	1464	25	of	of	IN
cord-010027-r0tl01kq	1464	26	gastric	gastric	JJ
cord-010027-r0tl01kq	1464	27	carcinogenesis	carcinogenesis	NN
cord-010027-r0tl01kq	1464	28	.	.	.
cord-010027-r0tl01kq	1465	1	The	the	DT
cord-010027-r0tl01kq	1465	2	aim	aim	NN
cord-010027-r0tl01kq	1465	3	of	of	IN
cord-010027-r0tl01kq	1465	4	this	this	DT
cord-010027-r0tl01kq	1465	5	study	study	NN
cord-010027-r0tl01kq	1465	6	was	be	VBD
cord-010027-r0tl01kq	1465	7	to	to	TO
cord-010027-r0tl01kq	1465	8	examine	examine	VB
cord-010027-r0tl01kq	1465	9	the	the	DT
cord-010027-r0tl01kq	1465	10	association	association	NN
cord-010027-r0tl01kq	1465	11	between	between	IN
cord-010027-r0tl01kq	1465	12	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1465	13	changes	change	NNS
cord-010027-r0tl01kq	1465	14	in	in	IN
cord-010027-r0tl01kq	1465	15	the	the	DT
cord-010027-r0tl01kq	1465	16	gastric	gastric	JJ
cord-010027-r0tl01kq	1465	17	mucosa	mucosa	JJ
cord-010027-r0tl01kq	1465	18	and	and	CC
cord-010027-r0tl01kq	1465	19	gastric	gastric	JJ
cord-010027-r0tl01kq	1465	20	H	h	NN
cord-010027-r0tl01kq	1465	21	pylori	pylori	NN
cord-010027-r0tl01kq	1465	22	infection	infection	NN
cord-010027-r0tl01kq	1465	23	in	in	IN
cord-010027-r0tl01kq	1465	24	Oman	Oman	NNP
cord-010027-r0tl01kq	1465	25	by	by	IN
cord-010027-r0tl01kq	1465	26	retrospective	retrospective	JJ
cord-010027-r0tl01kq	1465	27	examination	examination	NN
cord-010027-r0tl01kq	1465	28	of	of	IN
cord-010027-r0tl01kq	1465	29	the	the	DT
cord-010027-r0tl01kq	1465	30	gastric	gastric	JJ
cord-010027-r0tl01kq	1465	31	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1465	32	for	for	IN
cord-010027-r0tl01kq	1465	33	patients	patient	NNS
cord-010027-r0tl01kq	1465	34	presented	present	VBN
cord-010027-r0tl01kq	1465	35	to	to	IN
cord-010027-r0tl01kq	1465	36	Sultan	Sultan	NNP
cord-010027-r0tl01kq	1465	37	Qaboos	Qaboos	NNP
cord-010027-r0tl01kq	1465	38	University	University	NNP
cord-010027-r0tl01kq	1465	39	hospital	hospital	NN
cord-010027-r0tl01kq	1465	40	(	(	-LRB-
cord-010027-r0tl01kq	1465	41	SQUH	SQUH	NNP
cord-010027-r0tl01kq	1465	42	)	)	-RRB-
cord-010027-r0tl01kq	1465	43	in	in	IN
cord-010027-r0tl01kq	1465	44	2013	2013	CD
cord-010027-r0tl01kq	1465	45	.	.	.
cord-010027-r0tl01kq	1466	1	A	a	DT
cord-010027-r0tl01kq	1466	2	total	total	NN
cord-010027-r0tl01kq	1466	3	of	of	IN
cord-010027-r0tl01kq	1466	4	697	697	CD
cord-010027-r0tl01kq	1466	5	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1466	6	were	be	VBD
cord-010027-r0tl01kq	1466	7	studied	study	VBN
cord-010027-r0tl01kq	1466	8	with	with	IN
cord-010027-r0tl01kq	1466	9	a	a	DT
cord-010027-r0tl01kq	1466	10	prevalence	prevalence	NN
cord-010027-r0tl01kq	1466	11	of	of	IN
cord-010027-r0tl01kq	1466	12	H	h	NN
cord-010027-r0tl01kq	1466	13	pylori	pylori	NN
cord-010027-r0tl01kq	1466	14	infection	infection	NN
cord-010027-r0tl01kq	1466	15	in	in	IN
cord-010027-r0tl01kq	1466	16	34	34	CD
cord-010027-r0tl01kq	1466	17	%	%	NN
cord-010027-r0tl01kq	1466	18	with	with	IN
cord-010027-r0tl01kq	1466	19	about	about	RB
cord-010027-r0tl01kq	1466	20	13	13	CD
cord-010027-r0tl01kq	1466	21	%	%	NN
cord-010027-r0tl01kq	1466	22	showing	show	VBG
cord-010027-r0tl01kq	1466	23	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1466	24	changes	change	NNS
cord-010027-r0tl01kq	1466	25	,	,	,
cord-010027-r0tl01kq	1466	26	mainly	mainly	RB
cord-010027-r0tl01kq	1466	27	intestinal	intestinal	JJ
cord-010027-r0tl01kq	1466	28	metaplasia	metaplasia	NN
cord-010027-r0tl01kq	1466	29	in	in	IN
cord-010027-r0tl01kq	1466	30	10	10	CD
cord-010027-r0tl01kq	1466	31	%	%	NN
cord-010027-r0tl01kq	1466	32	out	out	IN
cord-010027-r0tl01kq	1466	33	of	of	IN
cord-010027-r0tl01kq	1466	34	the	the	DT
cord-010027-r0tl01kq	1466	35	H	h	NN
cord-010027-r0tl01kq	1466	36	pylori	pylori	NN
cord-010027-r0tl01kq	1466	37	positive	positive	JJ
cord-010027-r0tl01kq	1466	38	cases	case	NNS
cord-010027-r0tl01kq	1466	39	,	,	,
cord-010027-r0tl01kq	1466	40	a	a	DT
cord-010027-r0tl01kq	1466	41	few	few	JJ
cord-010027-r0tl01kq	1466	42	cases	case	NNS
cord-010027-r0tl01kq	1466	43	with	with	IN
cord-010027-r0tl01kq	1466	44	low	low	JJ
cord-010027-r0tl01kq	1466	45	grade	grade	NN
cord-010027-r0tl01kq	1466	46	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	1466	47	and	and	CC
cord-010027-r0tl01kq	1466	48	reactive	reactive	JJ
cord-010027-r0tl01kq	1466	49	atypia	atypia	NN
cord-010027-r0tl01kq	1466	50	.	.	.
cord-010027-r0tl01kq	1467	1	In	in	IN
cord-010027-r0tl01kq	1467	2	cocnlusion	cocnlusion	NN
cord-010027-r0tl01kq	1467	3	intestinal	intestinal	JJ
cord-010027-r0tl01kq	1467	4	metaplasia	metaplasia	NN
cord-010027-r0tl01kq	1467	5	was	be	VBD
cord-010027-r0tl01kq	1467	6	the	the	DT
cord-010027-r0tl01kq	1467	7	main	main	JJ
cord-010027-r0tl01kq	1467	8	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1467	9	change	change	NN
cord-010027-r0tl01kq	1467	10	that	that	WDT
cord-010027-r0tl01kq	1467	11	was	be	VBD
cord-010027-r0tl01kq	1467	12	related	relate	VBN
cord-010027-r0tl01kq	1467	13	to	to	IN
cord-010027-r0tl01kq	1467	14	H	h	NN
cord-010027-r0tl01kq	1467	15	pylori	pylori	NN
cord-010027-r0tl01kq	1467	16	infection	infection	NN
cord-010027-r0tl01kq	1467	17	.	.	.
cord-010027-r0tl01kq	1468	1	Further	further	JJ
cord-010027-r0tl01kq	1468	2	studues	studue	NNS
cord-010027-r0tl01kq	1468	3	are	be	VBP
cord-010027-r0tl01kq	1468	4	required	require	VBN
cord-010027-r0tl01kq	1468	5	to	to	TO
cord-010027-r0tl01kq	1468	6	investigate	investigate	VB
cord-010027-r0tl01kq	1468	7	the	the	DT
cord-010027-r0tl01kq	1468	8	relation	relation	NN
cord-010027-r0tl01kq	1468	9	between	between	IN
cord-010027-r0tl01kq	1468	10	H	h	NN
cord-010027-r0tl01kq	1468	11	pylori	pylori	NN
cord-010027-r0tl01kq	1468	12	infection	infection	NN
cord-010027-r0tl01kq	1468	13	and	and	CC
cord-010027-r0tl01kq	1468	14	the	the	DT
cord-010027-r0tl01kq	1468	15	progression	progression	NN
cord-010027-r0tl01kq	1468	16	to	to	IN
cord-010027-r0tl01kq	1468	17	gastric	gastric	JJ
cord-010027-r0tl01kq	1468	18	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1468	19	.	.	.
cord-010027-r0tl01kq	1469	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1469	2	of	of	IN
cord-010027-r0tl01kq	1469	3	the	the	DT
cord-010027-r0tl01kq	1469	4	study	study	NN
cord-010027-r0tl01kq	1469	5	:	:	:
cord-010027-r0tl01kq	1469	6	Low	low	JJ
cord-010027-r0tl01kq	1469	7	rectal	rectal	JJ
cord-010027-r0tl01kq	1469	8	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1469	9	may	may	MD
cord-010027-r0tl01kq	1469	10	require	require	VB
cord-010027-r0tl01kq	1469	11	abdomino	abdomino	NN
cord-010027-r0tl01kq	1469	12	-	-	HYPH
cord-010027-r0tl01kq	1469	13	perineal	perineal	NN
cord-010027-r0tl01kq	1469	14	excision	excision	NN
cord-010027-r0tl01kq	1469	15	of	of	IN
cord-010027-r0tl01kq	1469	16	the	the	DT
cord-010027-r0tl01kq	1469	17	rectum	rectum	NN
cord-010027-r0tl01kq	1469	18	(	(	-LRB-
cord-010027-r0tl01kq	1469	19	APER	APER	NNP
cord-010027-r0tl01kq	1469	20	)	)	-RRB-
cord-010027-r0tl01kq	1469	21	,	,	,
cord-010027-r0tl01kq	1469	22	which	which	WDT
cord-010027-r0tl01kq	1469	23	has	have	VBZ
cord-010027-r0tl01kq	1469	24	been	be	VBN
cord-010027-r0tl01kq	1469	25	associated	associate	VBN
cord-010027-r0tl01kq	1469	26	with	with	IN
cord-010027-r0tl01kq	1469	27	higher	high	JJR
cord-010027-r0tl01kq	1469	28	rates	rate	NNS
cord-010027-r0tl01kq	1469	29	of	of	IN
cord-010027-r0tl01kq	1469	30	tumour	tumour	NN
cord-010027-r0tl01kq	1469	31	perforation	perforation	NN
cord-010027-r0tl01kq	1469	32	and	and	CC
cord-010027-r0tl01kq	1469	33	circumferential	circumferential	JJ
cord-010027-r0tl01kq	1469	34	margin	margin	NN
cord-010027-r0tl01kq	1469	35	(	(	-LRB-
cord-010027-r0tl01kq	1469	36	CRM	CRM	NNP
cord-010027-r0tl01kq	1469	37	)	)	-RRB-
cord-010027-r0tl01kq	1469	38	involvement	involvement	NN
cord-010027-r0tl01kq	1469	39	than	than	IN
cord-010027-r0tl01kq	1469	40	anterior	anterior	JJ
cord-010027-r0tl01kq	1469	41	resection	resection	NN
cord-010027-r0tl01kq	1469	42	.	.	.
cord-010027-r0tl01kq	1470	1	This	this	DT
cord-010027-r0tl01kq	1470	2	increases	increase	VBZ
cord-010027-r0tl01kq	1470	3	the	the	DT
cord-010027-r0tl01kq	1470	4	risk	risk	NN
cord-010027-r0tl01kq	1470	5	of	of	IN
cord-010027-r0tl01kq	1470	6	local	local	JJ
cord-010027-r0tl01kq	1470	7	recurrence	recurrence	NN
cord-010027-r0tl01kq	1470	8	and	and	CC
cord-010027-r0tl01kq	1470	9	may	may	MD
cord-010027-r0tl01kq	1470	10	necessitate	necessitate	VB
cord-010027-r0tl01kq	1470	11	adjuvant	adjuvant	JJ
cord-010027-r0tl01kq	1470	12	treatment	treatment	NN
cord-010027-r0tl01kq	1470	13	.	.	.
cord-010027-r0tl01kq	1471	1	The	the	DT
cord-010027-r0tl01kq	1471	2	Extralevator	Extralevator	NNP
cord-010027-r0tl01kq	1471	3	Abdominoperineal	Abdominoperineal	NNP
cord-010027-r0tl01kq	1471	4	Excision	excision	NN
cord-010027-r0tl01kq	1471	5	of	of	IN
cord-010027-r0tl01kq	1471	6	Rectum	Rectum	NNP
cord-010027-r0tl01kq	1471	7	(	(	-LRB-
cord-010027-r0tl01kq	1471	8	eLAPE	elape	NN
cord-010027-r0tl01kq	1471	9	)	)	-RRB-
cord-010027-r0tl01kq	1472	1	in	in	IN
cord-010027-r0tl01kq	1472	2	the	the	DT
cord-010027-r0tl01kq	1472	3	prone	prone	JJ
cord-010027-r0tl01kq	1472	4	position	position	NN
cord-010027-r0tl01kq	1472	5	has	have	VBZ
cord-010027-r0tl01kq	1472	6	been	be	VBN
cord-010027-r0tl01kq	1472	7	found	find	VBN
cord-010027-r0tl01kq	1472	8	to	to	TO
cord-010027-r0tl01kq	1472	9	improve	improve	VB
cord-010027-r0tl01kq	1472	10	these	these	DT
cord-010027-r0tl01kq	1472	11	outcomes	outcome	NNS
cord-010027-r0tl01kq	1472	12	and	and	CC
cord-010027-r0tl01kq	1472	13	has	have	VBZ
cord-010027-r0tl01kq	1472	14	been	be	VBN
cord-010027-r0tl01kq	1472	15	encouraged	encourage	VBN
cord-010027-r0tl01kq	1472	16	by	by	IN
cord-010027-r0tl01kq	1472	17	the	the	DT
cord-010027-r0tl01kq	1472	18	Low	Low	NNP
cord-010027-r0tl01kq	1472	19	Rectal	Rectal	NNP
cord-010027-r0tl01kq	1472	20	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1472	21	National	National	NNP
cord-010027-r0tl01kq	1472	22	Development	Development	NNP
cord-010027-r0tl01kq	1472	23	Programme	Programme	NNP
cord-010027-r0tl01kq	1472	24	(	(	-LRB-
cord-010027-r0tl01kq	1472	25	LOREC	LOREC	NNP
cord-010027-r0tl01kq	1472	26	)	)	-RRB-
cord-010027-r0tl01kq	1472	27	.	.	.
cord-010027-r0tl01kq	1473	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1473	2	aimed	aim	VBD
cord-010027-r0tl01kq	1473	3	to	to	TO
cord-010027-r0tl01kq	1473	4	assess	assess	VB
cord-010027-r0tl01kq	1473	5	the	the	DT
cord-010027-r0tl01kq	1473	6	effect	effect	NN
cord-010027-r0tl01kq	1473	7	of	of	IN
cord-010027-r0tl01kq	1473	8	increasing	increase	VBG
cord-010027-r0tl01kq	1473	9	the	the	DT
cord-010027-r0tl01kq	1473	10	practice	practice	NN
cord-010027-r0tl01kq	1473	11	of	of	IN
cord-010027-r0tl01kq	1473	12	eLAPE	elape	NN
cord-010027-r0tl01kq	1473	13	on	on	IN
cord-010027-r0tl01kq	1473	14	the	the	DT
cord-010027-r0tl01kq	1473	15	histological	histological	JJ
cord-010027-r0tl01kq	1473	16	and	and	CC
cord-010027-r0tl01kq	1473	17	oncological	oncological	JJ
cord-010027-r0tl01kq	1473	18	outcomes	outcome	NNS
cord-010027-r0tl01kq	1473	19	in	in	IN
cord-010027-r0tl01kq	1473	20	these	these	DT
cord-010027-r0tl01kq	1473	21	cases	case	NNS
cord-010027-r0tl01kq	1473	22	in	in	IN
cord-010027-r0tl01kq	1473	23	the	the	DT
cord-010027-r0tl01kq	1473	24	Mid	Mid	NNP
cord-010027-r0tl01kq	1473	25	-	-	NNP
cord-010027-r0tl01kq	1473	26	Yorkshire	Yorkshire	NNP
cord-010027-r0tl01kq	1473	27	NHS	NHS	NNP
cord-010027-r0tl01kq	1473	28	trust	trust	NN
cord-010027-r0tl01kq	1473	29	,	,	,
cord-010027-r0tl01kq	1473	30	a	a	DT
cord-010027-r0tl01kq	1473	31	large	large	JJ
cord-010027-r0tl01kq	1473	32	District	District	NNP
cord-010027-r0tl01kq	1473	33	General	General	NNP
cord-010027-r0tl01kq	1473	34	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1473	35	.	.	.
cord-010027-r0tl01kq	1474	1	In	in	IN
cord-010027-r0tl01kq	1474	2	2011	2011	CD
cord-010027-r0tl01kq	1474	3	the	the	DT
cord-010027-r0tl01kq	1474	4	number	number	NN
cord-010027-r0tl01kq	1474	5	of	of	IN
cord-010027-r0tl01kq	1474	6	surgeons	surgeon	NNS
cord-010027-r0tl01kq	1474	7	routinely	routinely	RB
cord-010027-r0tl01kq	1474	8	performing	perform	VBG
cord-010027-r0tl01kq	1474	9	APER	APER	NNP
cord-010027-r0tl01kq	1474	10	was	be	VBD
cord-010027-r0tl01kq	1474	11	reduced	reduce	VBN
cord-010027-r0tl01kq	1474	12	and	and	CC
cord-010027-r0tl01kq	1474	13	all	all	PDT
cord-010027-r0tl01kq	1474	14	those	those	DT
cord-010027-r0tl01kq	1474	15	performing	perform	VBG
cord-010027-r0tl01kq	1474	16	the	the	DT
cord-010027-r0tl01kq	1474	17	procedure	procedure	NN
cord-010027-r0tl01kq	1474	18	had	have	VBD
cord-010027-r0tl01kq	1474	19	been	be	VBN
cord-010027-r0tl01kq	1474	20	trained	train	VBN
cord-010027-r0tl01kq	1474	21	in	in	IN
cord-010027-r0tl01kq	1474	22	the	the	DT
cord-010027-r0tl01kq	1474	23	cylindrical	cylindrical	JJ
cord-010027-r0tl01kq	1474	24	resection	resection	NN
cord-010027-r0tl01kq	1474	25	technique	technique	NN
cord-010027-r0tl01kq	1474	26	.	.	.
cord-010027-r0tl01kq	1475	1	Joint	joint	JJ
cord-010027-r0tl01kq	1475	2	operating	operating	NN
cord-010027-r0tl01kq	1475	3	and	and	CC
cord-010027-r0tl01kq	1475	4	laparoscopic	laparoscopic	JJ
cord-010027-r0tl01kq	1475	5	procedures	procedure	NNS
cord-010027-r0tl01kq	1475	6	were	be	VBD
cord-010027-r0tl01kq	1475	7	encouraged	encourage	VBN
cord-010027-r0tl01kq	1475	8	.	.	.
cord-010027-r0tl01kq	1476	1	A	a	DT
cord-010027-r0tl01kq	1476	2	retrospective	retrospective	JJ
cord-010027-r0tl01kq	1476	3	review	review	NN
cord-010027-r0tl01kq	1476	4	of	of	IN
cord-010027-r0tl01kq	1476	5	case	case	NN
cord-010027-r0tl01kq	1476	6	notes	note	NNS
cord-010027-r0tl01kq	1476	7	and	and	CC
cord-010027-r0tl01kq	1476	8	histological	histological	JJ
cord-010027-r0tl01kq	1476	9	reports	report	NNS
cord-010027-r0tl01kq	1476	10	between	between	IN
cord-010027-r0tl01kq	1476	11	2009	2009	CD
cord-010027-r0tl01kq	1476	12	and	and	CC
cord-010027-r0tl01kq	1476	13	2012	2012	CD
cord-010027-r0tl01kq	1476	14	was	be	VBD
cord-010027-r0tl01kq	1476	15	performed	perform	VBN
cord-010027-r0tl01kq	1476	16	(	(	-LRB-
cord-010027-r0tl01kq	1476	17	before	before	IN
cord-010027-r0tl01kq	1476	18	and	and	CC
cord-010027-r0tl01kq	1476	19	after	after	IN
cord-010027-r0tl01kq	1476	20	sub	sub	NN
cord-010027-r0tl01kq	1476	21	-	-	NN
cord-010027-r0tl01kq	1476	22	specialisation	specialisation	NN
cord-010027-r0tl01kq	1476	23	)	)	-RRB-
cord-010027-r0tl01kq	1476	24	.	.	.
cord-010027-r0tl01kq	1477	1	Patient	patient	JJ
cord-010027-r0tl01kq	1477	2	demographics	demographic	NNS
cord-010027-r0tl01kq	1477	3	,	,	,
cord-010027-r0tl01kq	1477	4	histological	histological	JJ
cord-010027-r0tl01kq	1477	5	findings	finding	NNS
cord-010027-r0tl01kq	1477	6	and	and	CC
cord-010027-r0tl01kq	1477	7	complications	complication	NNS
cord-010027-r0tl01kq	1477	8	including	include	VBG
cord-010027-r0tl01kq	1477	9	local	local	JJ
cord-010027-r0tl01kq	1477	10	recurrence	recurrence	NN
cord-010027-r0tl01kq	1477	11	were	be	VBD
cord-010027-r0tl01kq	1477	12	recorded	record	VBN
cord-010027-r0tl01kq	1477	13	.	.	.
cord-010027-r0tl01kq	1478	1	Summary	summary	NN
cord-010027-r0tl01kq	1478	2	of	of	IN
cord-010027-r0tl01kq	1478	3	Results	result	NNS
cord-010027-r0tl01kq	1478	4	:	:	:
cord-010027-r0tl01kq	1479	1	Between	between	IN
cord-010027-r0tl01kq	1479	2	2009	2009	CD
cord-010027-r0tl01kq	1479	3	and	and	CC
cord-010027-r0tl01kq	1479	4	2011	2011	CD
cord-010027-r0tl01kq	1479	5	,	,	,
cord-010027-r0tl01kq	1479	6	39	39	CD
cord-010027-r0tl01kq	1479	7	APERs	aper	NNS
cord-010027-r0tl01kq	1479	8	were	be	VBD
cord-010027-r0tl01kq	1479	9	performed	perform	VBN
cord-010027-r0tl01kq	1479	10	,	,	,
cord-010027-r0tl01kq	1479	11	with	with	IN
cord-010027-r0tl01kq	1479	12	tumour	tumour	NN
cord-010027-r0tl01kq	1479	13	perforation	perforation	NN
cord-010027-r0tl01kq	1479	14	in	in	IN
cord-010027-r0tl01kq	1479	15	5	5	CD
cord-010027-r0tl01kq	1479	16	(	(	-LRB-
cord-010027-r0tl01kq	1479	17	13	13	CD
cord-010027-r0tl01kq	1479	18	%	%	NN
cord-010027-r0tl01kq	1479	19	)	)	-RRB-
cord-010027-r0tl01kq	1479	20	and	and	CC
cord-010027-r0tl01kq	1479	21	CRM	CRM	NNP
cord-010027-r0tl01kq	1479	22	involvement	involvement	NN
cord-010027-r0tl01kq	1479	23	in	in	IN
cord-010027-r0tl01kq	1479	24	8	8	CD
cord-010027-r0tl01kq	1479	25	(	(	-LRB-
cord-010027-r0tl01kq	1479	26	21	21	CD
cord-010027-r0tl01kq	1479	27	%	%	NN
cord-010027-r0tl01kq	1479	28	)	)	-RRB-
cord-010027-r0tl01kq	1479	29	of	of	IN
cord-010027-r0tl01kq	1479	30	cases	case	NNS
cord-010027-r0tl01kq	1479	31	.	.	.
cord-010027-r0tl01kq	1480	1	After	after	IN
cord-010027-r0tl01kq	1480	2	sub	sub	NN
cord-010027-r0tl01kq	1480	3	-	-	NN
cord-010027-r0tl01kq	1480	4	specialisation	specialisation	NN
cord-010027-r0tl01kq	1480	5	,	,	,
cord-010027-r0tl01kq	1480	6	28	28	CD
cord-010027-r0tl01kq	1480	7	were	be	VBD
cord-010027-r0tl01kq	1480	8	performed	perform	VBN
cord-010027-r0tl01kq	1480	9	.	.	.
cord-010027-r0tl01kq	1481	1	None	none	NN
cord-010027-r0tl01kq	1481	2	were	be	VBD
cord-010027-r0tl01kq	1481	3	perforated	perforate	VBN
cord-010027-r0tl01kq	1481	4	and	and	CC
cord-010027-r0tl01kq	1481	5	2	2	CD
cord-010027-r0tl01kq	1481	6	cases	case	NNS
cord-010027-r0tl01kq	1481	7	(	(	-LRB-
cord-010027-r0tl01kq	1481	8	7	7	CD
cord-010027-r0tl01kq	1481	9	%	%	NN
cord-010027-r0tl01kq	1481	10	)	)	-RRB-
cord-010027-r0tl01kq	1481	11	showed	show	VBD
cord-010027-r0tl01kq	1481	12	margin	margin	NN
cord-010027-r0tl01kq	1481	13	involvement	involvement	NN
cord-010027-r0tl01kq	1481	14	.	.	.
cord-010027-r0tl01kq	1482	1	Local	local	JJ
cord-010027-r0tl01kq	1482	2	recurrence	recurrence	NN
cord-010027-r0tl01kq	1482	3	occurred	occur	VBD
cord-010027-r0tl01kq	1482	4	in	in	IN
cord-010027-r0tl01kq	1482	5	two	two	CD
cord-010027-r0tl01kq	1482	6	cases	case	NNS
cord-010027-r0tl01kq	1482	7	before	before	IN
cord-010027-r0tl01kq	1482	8	specialisation	specialisation	NN
cord-010027-r0tl01kq	1482	9	and	and	CC
cord-010027-r0tl01kq	1482	10	none	none	NN
cord-010027-r0tl01kq	1482	11	after	after	IN
cord-010027-r0tl01kq	1482	12	2011	2011	CD
cord-010027-r0tl01kq	1482	13	at	at	IN
cord-010027-r0tl01kq	1482	14	the	the	DT
cord-010027-r0tl01kq	1482	15	time	time	NN
cord-010027-r0tl01kq	1482	16	of	of	IN
cord-010027-r0tl01kq	1482	17	follow	follow	NN
cord-010027-r0tl01kq	1482	18	-	-	HYPH
cord-010027-r0tl01kq	1482	19	up	up	NN
cord-010027-r0tl01kq	1482	20	.	.	.
cord-010027-r0tl01kq	1483	1	Joint	joint	JJ
cord-010027-r0tl01kq	1483	2	operating	operating	NN
cord-010027-r0tl01kq	1483	3	and	and	CC
cord-010027-r0tl01kq	1483	4	subspecialisation	subspecialisation	NN
cord-010027-r0tl01kq	1483	5	increased	increase	VBD
cord-010027-r0tl01kq	1483	6	the	the	DT
cord-010027-r0tl01kq	1483	7	number	number	NN
cord-010027-r0tl01kq	1483	8	of	of	IN
cord-010027-r0tl01kq	1483	9	cases	case	NNS
cord-010027-r0tl01kq	1483	10	performed	perform	VBN
cord-010027-r0tl01kq	1483	11	by	by	IN
cord-010027-r0tl01kq	1483	12	each	each	DT
cord-010027-r0tl01kq	1483	13	surgeon	surgeon	NN
cord-010027-r0tl01kq	1483	14	,	,	,
cord-010027-r0tl01kq	1483	15	and	and	CC
cord-010027-r0tl01kq	1483	16	the	the	DT
cord-010027-r0tl01kq	1483	17	number	number	NN
cord-010027-r0tl01kq	1483	18	performed	perform	VBN
cord-010027-r0tl01kq	1483	19	laparoscopically	laparoscopically	RB
cord-010027-r0tl01kq	1483	20	.	.	.
cord-010027-r0tl01kq	1484	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1484	2	:	:	:
cord-010027-r0tl01kq	1484	3	eLAPE	elape	NN
cord-010027-r0tl01kq	1485	1	in	in	IN
cord-010027-r0tl01kq	1485	2	conjunction	conjunction	NN
cord-010027-r0tl01kq	1485	3	with	with	IN
cord-010027-r0tl01kq	1485	4	departmental	departmental	JJ
cord-010027-r0tl01kq	1485	5	restructuring	restructuring	NN
cord-010027-r0tl01kq	1485	6	significantly	significantly	RB
cord-010027-r0tl01kq	1485	7	improves	improve	VBZ
cord-010027-r0tl01kq	1485	8	immediate	immediate	JJ
cord-010027-r0tl01kq	1485	9	oncological	oncological	JJ
cord-010027-r0tl01kq	1485	10	outcomes	outcome	NNS
cord-010027-r0tl01kq	1485	11	in	in	IN
cord-010027-r0tl01kq	1485	12	a	a	DT
cord-010027-r0tl01kq	1485	13	DGH	DGH	NNP
cord-010027-r0tl01kq	1485	14	setting	setting	NN
cord-010027-r0tl01kq	1485	15	,	,	,
cord-010027-r0tl01kq	1485	16	with	with	IN
cord-010027-r0tl01kq	1485	17	no	no	DT
cord-010027-r0tl01kq	1485	18	effect	effect	NN
cord-010027-r0tl01kq	1485	19	on	on	IN
cord-010027-r0tl01kq	1485	20	30	30	CD
cord-010027-r0tl01kq	1485	21	day	day	NN
cord-010027-r0tl01kq	1485	22	mortality	mortality	NN
cord-010027-r0tl01kq	1485	23	.	.	.
cord-010027-r0tl01kq	1486	1	The	the	DT
cord-010027-r0tl01kq	1486	2	technique	technique	NN
cord-010027-r0tl01kq	1486	3	may	may	MD
cord-010027-r0tl01kq	1486	4	reduce	reduce	VB
cord-010027-r0tl01kq	1486	5	local	local	JJ
cord-010027-r0tl01kq	1486	6	recurrence	recurrence	NN
cord-010027-r0tl01kq	1486	7	,	,	,
cord-010027-r0tl01kq	1486	8	although	although	IN
cord-010027-r0tl01kq	1486	9	longer	long	JJR
cord-010027-r0tl01kq	1486	10	follow	follow	NN
cord-010027-r0tl01kq	1486	11	-	-	HYPH
cord-010027-r0tl01kq	1486	12	up	up	NN
cord-010027-r0tl01kq	1486	13	would	would	MD
cord-010027-r0tl01kq	1486	14	be	be	VB
cord-010027-r0tl01kq	1486	15	required	require	VBN
cord-010027-r0tl01kq	1486	16	.	.	.
cord-010027-r0tl01kq	1487	1	Background	background	NN
cord-010027-r0tl01kq	1487	2	:	:	:
cord-010027-r0tl01kq	1488	1	Systems	system	NNS
cord-010027-r0tl01kq	1488	2	biology	biology	NN
cord-010027-r0tl01kq	1488	3	uses	use	VBZ
cord-010027-r0tl01kq	1488	4	computational	computational	NN
cord-010027-r0tl01kq	1488	5	and	and	CC
cord-010027-r0tl01kq	1488	6	simulation	simulation	NN
cord-010027-r0tl01kq	1488	7	approaches	approach	NNS
cord-010027-r0tl01kq	1488	8	to	to	TO
cord-010027-r0tl01kq	1488	9	interrogate	interrogate	VB
cord-010027-r0tl01kq	1488	10	gene	gene	NN
cord-010027-r0tl01kq	1488	11	expression	expression	NN
cord-010027-r0tl01kq	1488	12	datasets	dataset	NNS
cord-010027-r0tl01kq	1488	13	and	and	CC
cord-010027-r0tl01kq	1488	14	explore	explore	VB
cord-010027-r0tl01kq	1488	15	biological	biological	JJ
cord-010027-r0tl01kq	1488	16	pathways	pathway	NNS
cord-010027-r0tl01kq	1488	17	.	.	.
cord-010027-r0tl01kq	1489	1	By	by	IN
cord-010027-r0tl01kq	1489	2	employing	employ	VBG
cord-010027-r0tl01kq	1489	3	systems	system	NNS
cord-010027-r0tl01kq	1489	4	biology	biology	NN
cord-010027-r0tl01kq	1489	5	and	and	CC
cord-010027-r0tl01kq	1489	6	data	datum	NNS
cord-010027-r0tl01kq	1489	7	mining	mining	NN
cord-010027-r0tl01kq	1489	8	tools	tool	NNS
cord-010027-r0tl01kq	1489	9	we	-PRON-	PRP
cord-010027-r0tl01kq	1489	10	can	can	MD
cord-010027-r0tl01kq	1489	11	identify	identify	VB
cord-010027-r0tl01kq	1489	12	new	new	JJ
cord-010027-r0tl01kq	1489	13	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1489	14	.	.	.
cord-010027-r0tl01kq	1490	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1490	2	objective	objective	NN
cord-010027-r0tl01kq	1490	3	was	be	VBD
cord-010027-r0tl01kq	1490	4	to	to	TO
cord-010027-r0tl01kq	1490	5	ascertain	ascertain	VB
cord-010027-r0tl01kq	1490	6	the	the	DT
cord-010027-r0tl01kq	1490	7	utility	utility	NN
cord-010027-r0tl01kq	1490	8	of	of	IN
cord-010027-r0tl01kq	1490	9	a	a	DT
cord-010027-r0tl01kq	1490	10	novel	novel	JJ
cord-010027-r0tl01kq	1490	11	panel	panel	NN
cord-010027-r0tl01kq	1490	12	of	of	IN
cord-010027-r0tl01kq	1490	13	systems	system	NNS
cord-010027-r0tl01kq	1490	14	biology	biology	NN
cord-010027-r0tl01kq	1490	15	derived	derive	VBN
cord-010027-r0tl01kq	1490	16	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1490	17	in	in	IN
cord-010027-r0tl01kq	1490	18	cervical	cervical	JJ
cord-010027-r0tl01kq	1490	19	pre	pre	JJ
cord-010027-r0tl01kq	1490	20	-	-	NN
cord-010027-r0tl01kq	1490	21	cancer	cancer	NN
cord-010027-r0tl01kq	1490	22	for	for	IN
cord-010027-r0tl01kq	1490	23	more	more	RBR
cord-010027-r0tl01kq	1490	24	accurate	accurate	JJ
cord-010027-r0tl01kq	1490	25	grading	grading	NN
cord-010027-r0tl01kq	1490	26	and	and	CC
cord-010027-r0tl01kq	1490	27	stratification	stratification	NN
cord-010027-r0tl01kq	1490	28	of	of	IN
cord-010027-r0tl01kq	1490	29	CIN	CIN	NNP
cord-010027-r0tl01kq	1490	30	disease	disease	NN
cord-010027-r0tl01kq	1490	31	.	.	.
cord-010027-r0tl01kq	1491	1	Methods	method	NNS
cord-010027-r0tl01kq	1491	2	:	:	:
cord-010027-r0tl01kq	1491	3	This	this	DT
cord-010027-r0tl01kq	1491	4	project	project	NN
cord-010027-r0tl01kq	1491	5	is	be	VBZ
cord-010027-r0tl01kq	1491	6	conducted	conduct	VBN
cord-010027-r0tl01kq	1491	7	within	within	IN
cord-010027-r0tl01kq	1491	8	the	the	DT
cord-010027-r0tl01kq	1491	9	framework	framework	NN
cord-010027-r0tl01kq	1491	10	of	of	IN
cord-010027-r0tl01kq	1491	11	an	an	DT
cord-010027-r0tl01kq	1491	12	FP7	FP7	NNP
cord-010027-r0tl01kq	1491	13	funded	funded	JJ
cord-010027-r0tl01kq	1491	14	programme	programme	NN
cord-010027-r0tl01kq	1491	15	"	"	``
cord-010027-r0tl01kq	1491	16	SYSTEMCERV	SYSTEMCERV	NNP
cord-010027-r0tl01kq	1491	17	"	"	''
cord-010027-r0tl01kq	1491	18	.	.	.
cord-010027-r0tl01kq	1492	1	Gene	gene	NN
cord-010027-r0tl01kq	1492	2	pathways	pathway	NNS
cord-010027-r0tl01kq	1492	3	were	be	VBD
cord-010027-r0tl01kq	1492	4	analysed	analyse	VBN
cord-010027-r0tl01kq	1492	5	using	use	VBG
cord-010027-r0tl01kq	1492	6	MATLAB	MATLAB	NNP
cord-010027-r0tl01kq	1492	7	and	and	CC
cord-010027-r0tl01kq	1492	8	SIRENE	SIRENE	NNP
cord-010027-r0tl01kq	1492	9	.	.	.
cord-010027-r0tl01kq	1493	1	Along	along	IN
cord-010027-r0tl01kq	1493	2	with	with	IN
cord-010027-r0tl01kq	1493	3	accessing	access	VBG
cord-010027-r0tl01kq	1493	4	KEGGS	KEGGS	NNP
cord-010027-r0tl01kq	1493	5	online	online	JJ
cord-010027-r0tl01kq	1493	6	database	database	NN
cord-010027-r0tl01kq	1493	7	for	for	IN
cord-010027-r0tl01kq	1493	8	gene	gene	NN
cord-010027-r0tl01kq	1493	9	prediction	prediction	NN
cord-010027-r0tl01kq	1493	10	and	and	CC
cord-010027-r0tl01kq	1493	11	DAVID	DAVID	NNP
cord-010027-r0tl01kq	1493	12	for	for	IN
cord-010027-r0tl01kq	1493	13	gene	gene	NN
cord-010027-r0tl01kq	1493	14	functional	functional	JJ
cord-010027-r0tl01kq	1493	15	classification	classification	NN
cord-010027-r0tl01kq	1493	16	,	,	,
cord-010027-r0tl01kq	1493	17	we	-PRON-	PRP
cord-010027-r0tl01kq	1493	18	identified	identify	VBD
cord-010027-r0tl01kq	1493	19	a	a	DT
cord-010027-r0tl01kq	1493	20	novel	novel	JJ
cord-010027-r0tl01kq	1493	21	panel	panel	NN
cord-010027-r0tl01kq	1493	22	of	of	IN
cord-010027-r0tl01kq	1493	23	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1493	24	.	.	.
cord-010027-r0tl01kq	1494	1	Gephi	Gephi	NNP
cord-010027-r0tl01kq	1494	2	software	software	NN
cord-010027-r0tl01kq	1494	3	was	be	VBD
cord-010027-r0tl01kq	1494	4	used	use	VBN
cord-010027-r0tl01kq	1494	5	to	to	TO
cord-010027-r0tl01kq	1494	6	visualise	visualise	VB
cord-010027-r0tl01kq	1494	7	communities	community	NNS
cord-010027-r0tl01kq	1494	8	of	of	IN
cord-010027-r0tl01kq	1494	9	genes	gene	NNS
cord-010027-r0tl01kq	1494	10	related	relate	VBN
cord-010027-r0tl01kq	1494	11	to	to	IN
cord-010027-r0tl01kq	1494	12	cervical	cervical	JJ
cord-010027-r0tl01kq	1494	13	pre	pre	JJ
cord-010027-r0tl01kq	1494	14	-	-	NN
cord-010027-r0tl01kq	1494	15	cancer	cancer	NN
cord-010027-r0tl01kq	1494	16	and	and	CC
cord-010027-r0tl01kq	1494	17	cancer	cancer	NN
cord-010027-r0tl01kq	1494	18	progression	progression	NN
cord-010027-r0tl01kq	1494	19	.	.	.
cord-010027-r0tl01kq	1495	1	Clinical	clinical	JJ
cord-010027-r0tl01kq	1495	2	validation	validation	NN
cord-010027-r0tl01kq	1495	3	was	be	VBD
cord-010027-r0tl01kq	1495	4	performed	perform	VBN
cord-010027-r0tl01kq	1495	5	by	by	IN
cord-010027-r0tl01kq	1495	6	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1495	7	on	on	IN
cord-010027-r0tl01kq	1495	8	a	a	DT
cord-010027-r0tl01kq	1495	9	range	range	NN
cord-010027-r0tl01kq	1495	10	of	of	IN
cord-010027-r0tl01kq	1495	11	cervical	cervical	JJ
cord-010027-r0tl01kq	1495	12	LLETZ	LLETZ	NNP
cord-010027-r0tl01kq	1495	13	specimens	specimen	NNS
cord-010027-r0tl01kq	1495	14	(	(	-LRB-
cord-010027-r0tl01kq	1495	15	Normal	normal	JJ
cord-010027-r0tl01kq	1495	16	,	,	,
cord-010027-r0tl01kq	1495	17	CIN1	CIN1	NNPS
cord-010027-r0tl01kq	1495	18	,	,	,
cord-010027-r0tl01kq	1495	19	CIN2	CIN2	NNP
cord-010027-r0tl01kq	1495	20	and	and	CC
cord-010027-r0tl01kq	1495	21	CIN3	CIN3	NNP
cord-010027-r0tl01kq	1495	22	)	)	-RRB-
cord-010027-r0tl01kq	1495	23	.	.	.
cord-010027-r0tl01kq	1496	1	All	all	DT
cord-010027-r0tl01kq	1496	2	patients	patient	NNS
cord-010027-r0tl01kq	1496	3	gave	give	VBD
cord-010027-r0tl01kq	1496	4	written	write	VBN
cord-010027-r0tl01kq	1496	5	informed	informed	JJ
cord-010027-r0tl01kq	1496	6	consent	consent	NN
cord-010027-r0tl01kq	1496	7	.	.	.
cord-010027-r0tl01kq	1497	1	In	in	IN
cord-010027-r0tl01kq	1497	2	parallel	parallel	NN
cord-010027-r0tl01kq	1497	3	,	,	,
cord-010027-r0tl01kq	1497	4	p16	p16	NN
cord-010027-r0tl01kq	1497	5	IHC	IHC	NNP
cord-010027-r0tl01kq	1497	6	was	be	VBD
cord-010027-r0tl01kq	1497	7	performed	perform	VBN
cord-010027-r0tl01kq	1497	8	on	on	IN
cord-010027-r0tl01kq	1497	9	all	all	DT
cord-010027-r0tl01kq	1497	10	specimens	specimen	NNS
cord-010027-r0tl01kq	1497	11	as	as	IN
cord-010027-r0tl01kq	1497	12	a	a	DT
cord-010027-r0tl01kq	1497	13	benchmark	benchmark	JJ
cord-010027-r0tl01kq	1497	14	stain	stain	NN
cord-010027-r0tl01kq	1497	15	.	.	.
cord-010027-r0tl01kq	1498	1	The	the	DT
cord-010027-r0tl01kq	1498	2	mortality	mortality	NN
cord-010027-r0tl01kq	1498	3	associated	associate	VBN
cord-010027-r0tl01kq	1498	4	with	with	IN
cord-010027-r0tl01kq	1498	5	cervical	cervical	JJ
cord-010027-r0tl01kq	1498	6	cancer	cancer	NN
cord-010027-r0tl01kq	1498	7	can	can	MD
cord-010027-r0tl01kq	1498	8	be	be	VB
cord-010027-r0tl01kq	1498	9	reduced	reduce	VBN
cord-010027-r0tl01kq	1498	10	if	if	IN
cord-010027-r0tl01kq	1498	11	the	the	DT
cord-010027-r0tl01kq	1498	12	disease	disease	NN
cord-010027-r0tl01kq	1498	13	is	be	VBZ
cord-010027-r0tl01kq	1498	14	detected	detect	VBN
cord-010027-r0tl01kq	1498	15	at	at	IN
cord-010027-r0tl01kq	1498	16	the	the	DT
cord-010027-r0tl01kq	1498	17	early	early	JJ
cord-010027-r0tl01kq	1498	18	stages	stage	NNS
cord-010027-r0tl01kq	1498	19	of	of	IN
cord-010027-r0tl01kq	1498	20	development	development	NN
cord-010027-r0tl01kq	1498	21	or	or	CC
cord-010027-r0tl01kq	1498	22	at	at	IN
cord-010027-r0tl01kq	1498	23	the	the	DT
cord-010027-r0tl01kq	1498	24	pre	pre	JJ
cord-010027-r0tl01kq	1498	25	-	-	JJ
cord-010027-r0tl01kq	1498	26	malignant	malignant	JJ
cord-010027-r0tl01kq	1498	27	stage	stage	NN
cord-010027-r0tl01kq	1498	28	.	.	.
cord-010027-r0tl01kq	1499	1	The	the	DT
cord-010027-r0tl01kq	1499	2	Pap	Pap	NNP
cord-010027-r0tl01kq	1499	3	smear	smear	NN
cord-010027-r0tl01kq	1499	4	is	be	VBZ
cord-010027-r0tl01kq	1499	5	the	the	DT
cord-010027-r0tl01kq	1499	6	current	current	JJ
cord-010027-r0tl01kq	1499	7	screening	screening	NN
cord-010027-r0tl01kq	1499	8	method	method	NN
cord-010027-r0tl01kq	1499	9	,	,	,
cord-010027-r0tl01kq	1499	10	but	but	CC
cord-010027-r0tl01kq	1499	11	is	be	VBZ
cord-010027-r0tl01kq	1499	12	highly	highly	RB
cord-010027-r0tl01kq	1499	13	subjective	subjective	JJ
cord-010027-r0tl01kq	1499	14	and	and	CC
cord-010027-r0tl01kq	1499	15	can	can	MD
cord-010027-r0tl01kq	1499	16	often	often	RB
cord-010027-r0tl01kq	1499	17	exhibit	exhibit	VB
cord-010027-r0tl01kq	1499	18	low	low	JJ
cord-010027-r0tl01kq	1499	19	specificity	specificity	NN
cord-010027-r0tl01kq	1499	20	and	and	CC
cord-010027-r0tl01kq	1499	21	sensitivity	sensitivity	NN
cord-010027-r0tl01kq	1499	22	.	.	.
cord-010027-r0tl01kq	1500	1	For	for	IN
cord-010027-r0tl01kq	1500	2	this	this	DT
cord-010027-r0tl01kq	1500	3	reason	reason	NN
cord-010027-r0tl01kq	1500	4	,	,	,
cord-010027-r0tl01kq	1500	5	either	either	CC
cord-010027-r0tl01kq	1500	6	a	a	DT
cord-010027-r0tl01kq	1500	7	replacement	replacement	NN
cord-010027-r0tl01kq	1500	8	or	or	CC
cord-010027-r0tl01kq	1500	9	supportive	supportive	JJ
cord-010027-r0tl01kq	1500	10	technique	technique	NN
cord-010027-r0tl01kq	1500	11	is	be	VBZ
cord-010027-r0tl01kq	1500	12	necessary	necessary	JJ
cord-010027-r0tl01kq	1500	13	to	to	TO
cord-010027-r0tl01kq	1500	14	improve	improve	VB
cord-010027-r0tl01kq	1500	15	the	the	DT
cord-010027-r0tl01kq	1500	16	quality	quality	NN
cord-010027-r0tl01kq	1500	17	of	of	IN
cord-010027-r0tl01kq	1500	18	cervical	cervical	JJ
cord-010027-r0tl01kq	1500	19	cancer	cancer	NN
cord-010027-r0tl01kq	1500	20	screening	screening	NN
cord-010027-r0tl01kq	1500	21	.	.	.
cord-010027-r0tl01kq	1501	1	Raman	Raman	NNP
cord-010027-r0tl01kq	1501	2	spectroscopy	spectroscopy	NN
cord-010027-r0tl01kq	1501	3	is	be	VBZ
cord-010027-r0tl01kq	1501	4	a	a	DT
cord-010027-r0tl01kq	1501	5	powerful	powerful	JJ
cord-010027-r0tl01kq	1501	6	tool	tool	NN
cord-010027-r0tl01kq	1501	7	that	that	WDT
cord-010027-r0tl01kq	1501	8	can	can	MD
cord-010027-r0tl01kq	1501	9	generate	generate	VB
cord-010027-r0tl01kq	1501	10	a	a	DT
cord-010027-r0tl01kq	1501	11	biochemical	biochemical	JJ
cord-010027-r0tl01kq	1501	12	fingerprint	fingerprint	NN
cord-010027-r0tl01kq	1501	13	of	of	IN
cord-010027-r0tl01kq	1501	14	a	a	DT
cord-010027-r0tl01kq	1501	15	sample	sample	NN
cord-010027-r0tl01kq	1501	16	in	in	IN
cord-010027-r0tl01kq	1501	17	a	a	DT
cord-010027-r0tl01kq	1501	18	rapid	rapid	JJ
cord-010027-r0tl01kq	1501	19	and	and	CC
cord-010027-r0tl01kq	1501	20	non	non	JJ
cord-010027-r0tl01kq	1501	21	-	-	JJ
cord-010027-r0tl01kq	1501	22	destructive	destructive	JJ
cord-010027-r0tl01kq	1501	23	manner	manner	NN
cord-010027-r0tl01kq	1501	24	.	.	.
cord-010027-r0tl01kq	1502	1	In	in	IN
cord-010027-r0tl01kq	1502	2	this	this	DT
cord-010027-r0tl01kq	1502	3	study	study	NN
cord-010027-r0tl01kq	1502	4	,	,	,
cord-010027-r0tl01kq	1502	5	Raman	Raman	NNP
cord-010027-r0tl01kq	1502	6	spectroscopy	spectroscopy	NN
cord-010027-r0tl01kq	1502	7	has	have	VBZ
cord-010027-r0tl01kq	1502	8	been	be	VBN
cord-010027-r0tl01kq	1502	9	applied	apply	VBN
cord-010027-r0tl01kq	1502	10	to	to	IN
cord-010027-r0tl01kq	1502	11	the	the	DT
cord-010027-r0tl01kq	1502	12	investigation	investigation	NN
cord-010027-r0tl01kq	1502	13	of	of	IN
cord-010027-r0tl01kq	1502	14	cervical	cervical	JJ
cord-010027-r0tl01kq	1502	15	cells	cell	NNS
cord-010027-r0tl01kq	1502	16	from	from	IN
cord-010027-r0tl01kq	1502	17	PreservCyt	PreservCyt	NNP
cord-010027-r0tl01kq	1502	18	specimens	specimen	NNS
cord-010027-r0tl01kq	1502	19	.	.	.
cord-010027-r0tl01kq	1503	1	Raman	Raman	NNP
cord-010027-r0tl01kq	1503	2	measurements	measurement	NNS
cord-010027-r0tl01kq	1503	3	were	be	VBD
cord-010027-r0tl01kq	1503	4	taken	take	VBN
cord-010027-r0tl01kq	1503	5	from	from	IN
cord-010027-r0tl01kq	1503	6	the	the	DT
cord-010027-r0tl01kq	1503	7	nuclei	nucleus	NNS
cord-010027-r0tl01kq	1503	8	of	of	IN
cord-010027-r0tl01kq	1503	9	cervical	cervical	JJ
cord-010027-r0tl01kq	1503	10	cells	cell	NNS
cord-010027-r0tl01kq	1503	11	from	from	IN
cord-010027-r0tl01kq	1503	12	normal	normal	JJ
cord-010027-r0tl01kq	1503	13	,	,	,
cord-010027-r0tl01kq	1503	14	CIN1	CIN1	NNPS
cord-010027-r0tl01kq	1503	15	,	,	,
cord-010027-r0tl01kq	1503	16	and	and	CC
cord-010027-r0tl01kq	1503	17	CIN3	CIN3	NNP
cord-010027-r0tl01kq	1503	18	samples	sample	NNS
cord-010027-r0tl01kq	1503	19	.	.	.
cord-010027-r0tl01kq	1504	1	These	these	DT
cord-010027-r0tl01kq	1504	2	spectra	spectrum	NNS
cord-010027-r0tl01kq	1504	3	were	be	VBD
cord-010027-r0tl01kq	1504	4	processed	process	VBN
cord-010027-r0tl01kq	1504	5	,	,	,
cord-010027-r0tl01kq	1504	6	analysed	analyse	VBN
cord-010027-r0tl01kq	1504	7	and	and	CC
cord-010027-r0tl01kq	1504	8	used	use	VBN
cord-010027-r0tl01kq	1504	9	to	to	TO
cord-010027-r0tl01kq	1504	10	define	define	VB
cord-010027-r0tl01kq	1504	11	a	a	DT
cord-010027-r0tl01kq	1504	12	spectral	spectral	JJ
cord-010027-r0tl01kq	1504	13	signature	signature	NN
cord-010027-r0tl01kq	1504	14	for	for	IN
cord-010027-r0tl01kq	1504	15	each	each	DT
cord-010027-r0tl01kq	1504	16	grade	grade	NN
cord-010027-r0tl01kq	1504	17	of	of	IN
cord-010027-r0tl01kq	1504	18	cervical	cervical	JJ
cord-010027-r0tl01kq	1504	19	disease	disease	NN
cord-010027-r0tl01kq	1504	20	.	.	.
cord-010027-r0tl01kq	1505	1	Principal	Principal	NNP
cord-010027-r0tl01kq	1505	2	Component	Component	NNP
cord-010027-r0tl01kq	1505	3	Analysis	Analysis	NNP
cord-010027-r0tl01kq	1505	4	(	(	-LRB-
cord-010027-r0tl01kq	1505	5	PCA	PCA	NNP
cord-010027-r0tl01kq	1505	6	)	)	-RRB-
cord-010027-r0tl01kq	1505	7	was	be	VBD
cord-010027-r0tl01kq	1505	8	used	use	VBN
cord-010027-r0tl01kq	1505	9	to	to	TO
cord-010027-r0tl01kq	1505	10	discriminate	discriminate	VB
cord-010027-r0tl01kq	1505	11	between	between	IN
cord-010027-r0tl01kq	1505	12	the	the	DT
cord-010027-r0tl01kq	1505	13	two	two	CD
cord-010027-r0tl01kq	1505	14	data	datum	NNS
cord-010027-r0tl01kq	1505	15	sets	set	NNS
cord-010027-r0tl01kq	1505	16	.	.	.
cord-010027-r0tl01kq	1506	1	Distinct	distinct	JJ
cord-010027-r0tl01kq	1506	2	Raman	Raman	NNP
cord-010027-r0tl01kq	1506	3	spectral	spectral	JJ
cord-010027-r0tl01kq	1506	4	differences	difference	NNS
cord-010027-r0tl01kq	1506	5	were	be	VBD
cord-010027-r0tl01kq	1506	6	detected	detect	VBN
cord-010027-r0tl01kq	1506	7	between	between	IN
cord-010027-r0tl01kq	1506	8	normal	normal	JJ
cord-010027-r0tl01kq	1506	9	,	,	,
cord-010027-r0tl01kq	1506	10	CIN1	CIN1	NNPS
cord-010027-r0tl01kq	1506	11	and	and	CC
cord-010027-r0tl01kq	1506	12	CIN3	CIN3	NNP
cord-010027-r0tl01kq	1506	13	cells	cell	NNS
cord-010027-r0tl01kq	1506	14	.	.	.
cord-010027-r0tl01kq	1507	1	Notably	notably	RB
cord-010027-r0tl01kq	1507	2	,	,	,
cord-010027-r0tl01kq	1507	3	it	-PRON-	PRP
cord-010027-r0tl01kq	1507	4	was	be	VBD
cord-010027-r0tl01kq	1507	5	possible	possible	JJ
cord-010027-r0tl01kq	1507	6	to	to	TO
cord-010027-r0tl01kq	1507	7	observe	observe	VB
cord-010027-r0tl01kq	1507	8	spectral	spectral	JJ
cord-010027-r0tl01kq	1507	9	peak	peak	NN
cord-010027-r0tl01kq	1507	10	shifts	shift	NNS
cord-010027-r0tl01kq	1507	11	representing	represent	VBG
cord-010027-r0tl01kq	1507	12	fluctuations	fluctuation	NNS
cord-010027-r0tl01kq	1507	13	in	in	IN
cord-010027-r0tl01kq	1507	14	Guanine	Guanine	NNP
cord-010027-r0tl01kq	1507	15	(	(	-LRB-
cord-010027-r0tl01kq	1507	16	DNA	DNA	NNP
cord-010027-r0tl01kq	1507	17	/	/	SYM
cord-010027-r0tl01kq	1507	18	RNA	RNA	NNP
cord-010027-r0tl01kq	1507	19	)	)	-RRB-
cord-010027-r0tl01kq	1507	20	,	,	,
cord-010027-r0tl01kq	1507	21	CH	CH	NNP
cord-010027-r0tl01kq	1507	22	deformation	deformation	NN
cord-010027-r0tl01kq	1507	23	in	in	IN
cord-010027-r0tl01kq	1507	24	proteins	protein	NNS
cord-010027-r0tl01kq	1507	25	and	and	CC
cord-010027-r0tl01kq	1507	26	carbohydrates	carbohydrate	NNS
cord-010027-r0tl01kq	1507	27	,	,	,
cord-010027-r0tl01kq	1507	28	Carbon	carbon	NN
cord-010027-r0tl01kq	1507	29	-	-	HYPH
cord-010027-r0tl01kq	1507	30	carbon	carbon	NN
cord-010027-r0tl01kq	1507	31	double	double	JJ
cord-010027-r0tl01kq	1507	32	bonds	bond	NNS
cord-010027-r0tl01kq	1507	33	in	in	IN
cord-010027-r0tl01kq	1507	34	Phenylalanine	Phenylalanine	NNP
cord-010027-r0tl01kq	1507	35	,	,	,
cord-010027-r0tl01kq	1507	36	Tyrosine	Tyrosine	NNP
cord-010027-r0tl01kq	1507	37	and	and	CC
cord-010027-r0tl01kq	1507	38	Tryptophan	tryptophan	NN
cord-010027-r0tl01kq	1507	39	,	,	,
cord-010027-r0tl01kq	1507	40	and	and	CC
cord-010027-r0tl01kq	1507	41	Amide	Amide	NNP
cord-010027-r0tl01kq	1507	42	I.	I.	NNP
cord-010027-r0tl01kq	1508	1	The	the	DT
cord-010027-r0tl01kq	1508	2	PCA	PCA	NNP
cord-010027-r0tl01kq	1508	3	showed	show	VBD
cord-010027-r0tl01kq	1508	4	an	an	DT
cord-010027-r0tl01kq	1508	5	excellent	excellent	JJ
cord-010027-r0tl01kq	1508	6	discrimination	discrimination	NN
cord-010027-r0tl01kq	1508	7	between	between	IN
cord-010027-r0tl01kq	1508	8	the	the	DT
cord-010027-r0tl01kq	1508	9	data	data	NN
cord-010027-r0tl01kq	1508	10	sets	set	NNS
cord-010027-r0tl01kq	1508	11	.	.	.
cord-010027-r0tl01kq	1509	1	This	this	DT
cord-010027-r0tl01kq	1509	2	study	study	NN
cord-010027-r0tl01kq	1509	3	has	have	VBZ
cord-010027-r0tl01kq	1509	4	shown	show	VBN
cord-010027-r0tl01kq	1509	5	that	that	IN
cord-010027-r0tl01kq	1509	6	Raman	Raman	NNP
cord-010027-r0tl01kq	1509	7	spectroscopy	spectroscopy	NN
cord-010027-r0tl01kq	1509	8	can	can	MD
cord-010027-r0tl01kq	1509	9	detect	detect	VB
cord-010027-r0tl01kq	1509	10	subtle	subtle	JJ
cord-010027-r0tl01kq	1509	11	changes	change	NNS
cord-010027-r0tl01kq	1509	12	between	between	IN
cord-010027-r0tl01kq	1509	13	cervical	cervical	JJ
cord-010027-r0tl01kq	1509	14	cells	cell	NNS
cord-010027-r0tl01kq	1509	15	,	,	,
cord-010027-r0tl01kq	1509	16	and	and	CC
cord-010027-r0tl01kq	1509	17	may	may	MD
cord-010027-r0tl01kq	1509	18	be	be	VB
cord-010027-r0tl01kq	1509	19	a	a	DT
cord-010027-r0tl01kq	1509	20	powerful	powerful	JJ
cord-010027-r0tl01kq	1509	21	tool	tool	NN
cord-010027-r0tl01kq	1509	22	for	for	IN
cord-010027-r0tl01kq	1509	23	improved	improved	JJ
cord-010027-r0tl01kq	1509	24	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1509	25	of	of	IN
cord-010027-r0tl01kq	1509	26	cervical	cervical	JJ
cord-010027-r0tl01kq	1509	27	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	1509	28	.	.	.
cord-010027-r0tl01kq	1510	1	Background	background	NN
cord-010027-r0tl01kq	1510	2	:	:	:
cord-010027-r0tl01kq	1511	1	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1511	2	and	and	CC
cord-010027-r0tl01kq	1511	3	MAD2	MAD2	NNPS
cord-010027-r0tl01kq	1511	4	are	be	VBP
cord-010027-r0tl01kq	1511	5	two	two	CD
cord-010027-r0tl01kq	1511	6	potential	potential	JJ
cord-010027-r0tl01kq	1511	7	prognostic	prognostic	JJ
cord-010027-r0tl01kq	1511	8	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1511	9	that	that	WDT
cord-010027-r0tl01kq	1511	10	have	have	VBP
cord-010027-r0tl01kq	1511	11	been	be	VBN
cord-010027-r0tl01kq	1511	12	investigated	investigate	VBN
cord-010027-r0tl01kq	1511	13	in	in	IN
cord-010027-r0tl01kq	1511	14	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1511	15	cancer	cancer	NN
cord-010027-r0tl01kq	1511	16	.	.	.
cord-010027-r0tl01kq	1512	1	High	high	JJ
cord-010027-r0tl01kq	1512	2	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1512	3	and	and	CC
cord-010027-r0tl01kq	1512	4	Low	low	JJ
cord-010027-r0tl01kq	1512	5	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1512	6	IHC	IHC	NNP
cord-010027-r0tl01kq	1512	7	staining	staining	NN
cord-010027-r0tl01kq	1512	8	is	be	VBZ
cord-010027-r0tl01kq	1512	9	associated	associate	VBN
cord-010027-r0tl01kq	1512	10	with	with	IN
cord-010027-r0tl01kq	1512	11	reduced	reduce	VBN
cord-010027-r0tl01kq	1512	12	PFS	PFS	NNP
cord-010027-r0tl01kq	1512	13	,	,	,
cord-010027-r0tl01kq	1512	14	both	both	DT
cord-010027-r0tl01kq	1512	15	markers	marker	NNS
cord-010027-r0tl01kq	1512	16	are	be	VBP
cord-010027-r0tl01kq	1512	17	also	also	RB
cord-010027-r0tl01kq	1512	18	linked	link	VBN
cord-010027-r0tl01kq	1512	19	to	to	IN
cord-010027-r0tl01kq	1512	20	paclitaxel	paclitaxel	NNP
cord-010027-r0tl01kq	1512	21	chemoresistance	chemoresistance	NNP
cord-010027-r0tl01kq	1512	22	.	.	.
cord-010027-r0tl01kq	1513	1	The	the	DT
cord-010027-r0tl01kq	1513	2	main	main	JJ
cord-010027-r0tl01kq	1513	3	objective	objective	NN
cord-010027-r0tl01kq	1513	4	of	of	IN
cord-010027-r0tl01kq	1513	5	this	this	DT
cord-010027-r0tl01kq	1513	6	study	study	NN
cord-010027-r0tl01kq	1513	7	was	be	VBD
cord-010027-r0tl01kq	1513	8	to	to	TO
cord-010027-r0tl01kq	1513	9	assess	assess	VB
cord-010027-r0tl01kq	1513	10	the	the	DT
cord-010027-r0tl01kq	1513	11	in	in	FW
cord-010027-r0tl01kq	1513	12	vitro	vitro	FW
cord-010027-r0tl01kq	1513	13	relationship	relationship	NN
cord-010027-r0tl01kq	1513	14	between	between	IN
cord-010027-r0tl01kq	1513	15	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1513	16	and	and	CC
cord-010027-r0tl01kq	1513	17	MyD88	MyD88	NNP
cord-010027-r0tl01kq	1513	18	,	,	,
cord-010027-r0tl01kq	1513	19	through	through	IN
cord-010027-r0tl01kq	1513	20	alteration	alteration	NN
cord-010027-r0tl01kq	1513	21	of	of	IN
cord-010027-r0tl01kq	1513	22	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1513	23	,	,	,
cord-010027-r0tl01kq	1513	24	MyD88	MyD88	NNPS
cord-010027-r0tl01kq	1513	25	or	or	CC
cord-010027-r0tl01kq	1513	26	its	-PRON-	PRP$
cord-010027-r0tl01kq	1513	27	receptor	receptor	NN
cord-010027-r0tl01kq	1513	28	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1513	29	in	in	IN
cord-010027-r0tl01kq	1513	30	two	two	CD
cord-010027-r0tl01kq	1513	31	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1513	32	cancer	cancer	NN
cord-010027-r0tl01kq	1513	33	cell	cell	NN
cord-010027-r0tl01kq	1513	34	lines	line	NNS
cord-010027-r0tl01kq	1513	35	using	use	VBG
cord-010027-r0tl01kq	1513	36	siRNA	siRNA	NNP
cord-010027-r0tl01kq	1513	37	targeting	target	VBG
cord-010027-r0tl01kq	1513	38	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1513	39	,	,	,
cord-010027-r0tl01kq	1513	40	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1513	41	or	or	CC
cord-010027-r0tl01kq	1513	42	MyD88	MyD88	NNPS
cord-010027-r0tl01kq	1513	43	and	and	CC
cord-010027-r0tl01kq	1513	44	a	a	DT
cord-010027-r0tl01kq	1513	45	MyD88	myd88	JJ
cord-010027-r0tl01kq	1513	46	overexpression	overexpression	NN
cord-010027-r0tl01kq	1513	47	plasmid	plasmid	NN
cord-010027-r0tl01kq	1513	48	vector	vector	NN
cord-010027-r0tl01kq	1513	49	.	.	.
cord-010027-r0tl01kq	1514	1	Following	follow	VBG
cord-010027-r0tl01kq	1514	2	overexpression	overexpression	NN
cord-010027-r0tl01kq	1514	3	/	/	SYM
cord-010027-r0tl01kq	1514	4	siRNA	siRNA	NNP
cord-010027-r0tl01kq	1514	5	knockdown	knockdown	NN
cord-010027-r0tl01kq	1514	6	procedures	procedure	NNS
cord-010027-r0tl01kq	1514	7	,	,	,
cord-010027-r0tl01kq	1514	8	MyD88	MyD88	NNPS
cord-010027-r0tl01kq	1514	9	,	,	,
cord-010027-r0tl01kq	1514	10	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1514	11	and	and	CC
cord-010027-r0tl01kq	1514	12	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1514	13	expression	expression	NN
cord-010027-r0tl01kq	1514	14	was	be	VBD
cord-010027-r0tl01kq	1514	15	assessed	assess	VBN
cord-010027-r0tl01kq	1514	16	through	through	IN
cord-010027-r0tl01kq	1514	17	qPCR	qpcr	JJ
cord-010027-r0tl01kq	1514	18	and	and	CC
cord-010027-r0tl01kq	1514	19	Western	Western	NNP
cord-010027-r0tl01kq	1514	20	Blot	Blot	NNP
cord-010027-r0tl01kq	1514	21	analysis	analysis	NN
cord-010027-r0tl01kq	1514	22	.	.	.
cord-010027-r0tl01kq	1515	1	Mir-433	Mir-433	NNP
cord-010027-r0tl01kq	1515	2	,	,	,
cord-010027-r0tl01kq	1515	3	Mir-21	Mir-21	NNP
cord-010027-r0tl01kq	1515	4	and	and	CC
cord-010027-r0tl01kq	1515	5	Mir-146a	Mir-146a	NNP
cord-010027-r0tl01kq	1515	6	gene	gene	NN
cord-010027-r0tl01kq	1515	7	expression	expression	NN
cord-010027-r0tl01kq	1515	8	was	be	VBD
cord-010027-r0tl01kq	1515	9	also	also	RB
cord-010027-r0tl01kq	1515	10	assessed	assess	VBN
cord-010027-r0tl01kq	1515	11	by	by	IN
cord-010027-r0tl01kq	1515	12	qPCR	qPCR	NNP
cord-010027-r0tl01kq	1515	13	.	.	.
cord-010027-r0tl01kq	1516	1	Furthermore	furthermore	RB
cord-010027-r0tl01kq	1516	2	the	the	DT
cord-010027-r0tl01kq	1516	3	effect	effect	NN
cord-010027-r0tl01kq	1516	4	of	of	IN
cord-010027-r0tl01kq	1516	5	TLR4/	TLR4/	NNP
cord-010027-r0tl01kq	1516	6	MyD88	MyD88	NNP
cord-010027-r0tl01kq	1516	7	knockdown	knockdown	NN
cord-010027-r0tl01kq	1516	8	on	on	IN
cord-010027-r0tl01kq	1516	9	chemoresponse	chemoresponse	NN
cord-010027-r0tl01kq	1516	10	was	be	VBD
cord-010027-r0tl01kq	1516	11	assessed	assess	VBN
cord-010027-r0tl01kq	1516	12	in	in	IN
cord-010027-r0tl01kq	1516	13	SKOV-3	SKOV-3	NNP
cord-010027-r0tl01kq	1516	14	cells	cell	NNS
cord-010027-r0tl01kq	1516	15	using	use	VBG
cord-010027-r0tl01kq	1516	16	the	the	DT
cord-010027-r0tl01kq	1516	17	CCK-8	CCK-8	NNP
cord-010027-r0tl01kq	1516	18	assay	assay	NN
cord-010027-r0tl01kq	1516	19	.	.	.
cord-010027-r0tl01kq	1517	1	Results	result	NNS
cord-010027-r0tl01kq	1517	2	/	/	SYM
cord-010027-r0tl01kq	1517	3	Discussion	discussion	NN
cord-010027-r0tl01kq	1517	4	:	:	:
cord-010027-r0tl01kq	1518	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1518	2	was	be	VBD
cord-010027-r0tl01kq	1518	3	found	find	VBN
cord-010027-r0tl01kq	1518	4	that	that	IN
cord-010027-r0tl01kq	1518	5	knockdown	knockdown	NN
cord-010027-r0tl01kq	1518	6	or	or	CC
cord-010027-r0tl01kq	1518	7	overexpression	overexpression	NN
cord-010027-r0tl01kq	1518	8	of	of	IN
cord-010027-r0tl01kq	1518	9	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1518	10	in	in	IN
cord-010027-r0tl01kq	1518	11	SKOV-3	SKOV-3	NNP
cord-010027-r0tl01kq	1518	12	or	or	CC
cord-010027-r0tl01kq	1518	13	A2780	a2780	NN
cord-010027-r0tl01kq	1518	14	cells	cell	NNS
cord-010027-r0tl01kq	1518	15	respectively	respectively	RB
cord-010027-r0tl01kq	1518	16	or	or	CC
cord-010027-r0tl01kq	1518	17	knockdown	knockdown	NN
cord-010027-r0tl01kq	1518	18	of	of	IN
cord-010027-r0tl01kq	1518	19	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1518	20	in	in	IN
cord-010027-r0tl01kq	1518	21	SKOV-3	SKOV-3	NNP
cord-010027-r0tl01kq	1518	22	cells	cell	NNS
cord-010027-r0tl01kq	1518	23	had	have	VBD
cord-010027-r0tl01kq	1518	24	no	no	DT
cord-010027-r0tl01kq	1518	25	effect	effect	NN
cord-010027-r0tl01kq	1518	26	on	on	IN
cord-010027-r0tl01kq	1518	27	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1518	28	expression	expression	NN
cord-010027-r0tl01kq	1518	29	or	or	CC
cord-010027-r0tl01kq	1518	30	the	the	DT
cord-010027-r0tl01kq	1518	31	expression	expression	NN
cord-010027-r0tl01kq	1518	32	of	of	IN
cord-010027-r0tl01kq	1518	33	Mir-21	Mir-21	NNP
cord-010027-r0tl01kq	1518	34	,	,	,
cord-010027-r0tl01kq	1518	35	Mir-433	Mir-433	NNP
cord-010027-r0tl01kq	1518	36	and	and	CC
cord-010027-r0tl01kq	1518	37	Mir-146a	Mir-146a	NNP
cord-010027-r0tl01kq	1518	38	.	.	.
cord-010027-r0tl01kq	1519	1	Interestingly	interestingly	RB
cord-010027-r0tl01kq	1519	2	however	however	RB
cord-010027-r0tl01kq	1519	3	knockdown	knockdown	NN
cord-010027-r0tl01kq	1519	4	of	of	IN
cord-010027-r0tl01kq	1519	5	MAD2	MAD2	NNPS
cord-010027-r0tl01kq	1519	6	in	in	IN
cord-010027-r0tl01kq	1519	7	both	both	DT
cord-010027-r0tl01kq	1519	8	cell	cell	NN
cord-010027-r0tl01kq	1519	9	lines	line	NNS
cord-010027-r0tl01kq	1519	10	induced	induce	VBD
cord-010027-r0tl01kq	1519	11	a	a	DT
cord-010027-r0tl01kq	1519	12	3	3	CD
cord-010027-r0tl01kq	1519	13	fold	fold	JJ
cord-010027-r0tl01kq	1519	14	increase	increase	NN
cord-010027-r0tl01kq	1519	15	in	in	IN
cord-010027-r0tl01kq	1519	16	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1519	17	expression	expression	NN
cord-010027-r0tl01kq	1519	18	,	,	,
cord-010027-r0tl01kq	1519	19	furthermore	furthermore	RB
cord-010027-r0tl01kq	1519	20	knockdown	knockdown	NN
cord-010027-r0tl01kq	1519	21	of	of	IN
cord-010027-r0tl01kq	1519	22	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1519	23	in	in	IN
cord-010027-r0tl01kq	1519	24	SKOV-3	SKOV-3	NNP
cord-010027-r0tl01kq	1519	25	cells	cell	NNS
cord-010027-r0tl01kq	1519	26	was	be	VBD
cord-010027-r0tl01kq	1519	27	shown	show	VBN
cord-010027-r0tl01kq	1519	28	to	to	TO
cord-010027-r0tl01kq	1519	29	restore	restore	VB
cord-010027-r0tl01kq	1519	30	chemosensitivity	chemosensitivity	NN
cord-010027-r0tl01kq	1519	31	to	to	IN
cord-010027-r0tl01kq	1519	32	paclitaxel	paclitaxel	VB
cord-010027-r0tl01kq	1519	33	.	.	.
cord-010027-r0tl01kq	1520	1	The	the	DT
cord-010027-r0tl01kq	1520	2	results	result	NNS
cord-010027-r0tl01kq	1520	3	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	1520	4	a	a	DT
cord-010027-r0tl01kq	1520	5	potential	potential	NN
cord-010027-r0tl01kq	1520	6	in	in	IN
cord-010027-r0tl01kq	1520	7	vitro	vitro	FW
cord-010027-r0tl01kq	1520	8	link	link	NN
cord-010027-r0tl01kq	1520	9	between	between	IN
cord-010027-r0tl01kq	1520	10	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1520	11	and	and	CC
cord-010027-r0tl01kq	1520	12	MAD2	MAD2	NNPS
cord-010027-r0tl01kq	1520	13	and	and	CC
cord-010027-r0tl01kq	1520	14	support	support	VB
cord-010027-r0tl01kq	1520	15	a	a	DT
cord-010027-r0tl01kq	1520	16	role	role	NN
cord-010027-r0tl01kq	1520	17	for	for	IN
cord-010027-r0tl01kq	1520	18	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1520	19	in	in	IN
cord-010027-r0tl01kq	1520	20	paclitaxel	paclitaxel	NNP
cord-010027-r0tl01kq	1520	21	chemoresistance	chemoresistance	NNP
cord-010027-r0tl01kq	1520	22	.	.	.
cord-010027-r0tl01kq	1521	1	Background	background	NN
cord-010027-r0tl01kq	1521	2	:	:	:
cord-010027-r0tl01kq	1522	1	The	the	DT
cord-010027-r0tl01kq	1522	2	prognosis	prognosis	NN
cord-010027-r0tl01kq	1522	3	of	of	IN
cord-010027-r0tl01kq	1522	4	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1522	5	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1522	6	cancer	cancer	NN
cord-010027-r0tl01kq	1522	7	is	be	VBZ
cord-010027-r0tl01kq	1522	8	poor	poor	JJ
cord-010027-r0tl01kq	1522	9	in	in	IN
cord-010027-r0tl01kq	1522	10	part	part	NN
cord-010027-r0tl01kq	1522	11	due	due	IN
cord-010027-r0tl01kq	1522	12	to	to	IN
cord-010027-r0tl01kq	1522	13	the	the	DT
cord-010027-r0tl01kq	1522	14	high	high	JJ
cord-010027-r0tl01kq	1522	15	frequency	frequency	NN
cord-010027-r0tl01kq	1522	16	of	of	IN
cord-010027-r0tl01kq	1522	17	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	1522	18	.	.	.
cord-010027-r0tl01kq	1523	1	Recent	recent	JJ
cord-010027-r0tl01kq	1523	2	evidence	evidence	NN
cord-010027-r0tl01kq	1523	3	points	point	VBZ
cord-010027-r0tl01kq	1523	4	to	to	IN
cord-010027-r0tl01kq	1523	5	the	the	DT
cord-010027-r0tl01kq	1523	6	Toll	Toll	NNP
cord-010027-r0tl01kq	1523	7	-	-	HYPH
cord-010027-r0tl01kq	1523	8	like	like	JJ
cord-010027-r0tl01kq	1523	9	receptor-4	receptor-4	NNP
cord-010027-r0tl01kq	1523	10	(	(	-LRB-
cord-010027-r0tl01kq	1523	11	TLR4	TLR4	NNP
cord-010027-r0tl01kq	1523	12	)	)	-RRB-
cord-010027-r0tl01kq	1523	13	,	,	,
cord-010027-r0tl01kq	1523	14	and	and	CC
cord-010027-r0tl01kq	1523	15	particularly	particularly	RB
cord-010027-r0tl01kq	1523	16	its	-PRON-	PRP$
cord-010027-r0tl01kq	1523	17	adaptor	adaptor	NN
cord-010027-r0tl01kq	1523	18	protein	protein	NN
cord-010027-r0tl01kq	1523	19	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1523	20	,	,	,
cord-010027-r0tl01kq	1523	21	as	as	IN
cord-010027-r0tl01kq	1523	22	one	one	CD
cord-010027-r0tl01kq	1523	23	potential	potential	JJ
cord-010027-r0tl01kq	1523	24	mediator	mediator	NN
cord-010027-r0tl01kq	1523	25	of	of	IN
cord-010027-r0tl01kq	1523	26	this	this	DT
cord-010027-r0tl01kq	1523	27	resistance	resistance	NN
cord-010027-r0tl01kq	1523	28	.	.	.
cord-010027-r0tl01kq	1524	1	Downregulation	Downregulation	NNP
cord-010027-r0tl01kq	1524	2	of	of	IN
cord-010027-r0tl01kq	1524	3	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1524	4	,	,	,
cord-010027-r0tl01kq	1524	5	a	a	DT
cord-010027-r0tl01kq	1524	6	key	key	JJ
cord-010027-r0tl01kq	1524	7	component	component	NN
cord-010027-r0tl01kq	1524	8	of	of	IN
cord-010027-r0tl01kq	1524	9	the	the	DT
cord-010027-r0tl01kq	1524	10	spindle	spindle	NN
cord-010027-r0tl01kq	1524	11	assembly	assembly	NN
cord-010027-r0tl01kq	1524	12	checkpoint	checkpoint	NN
cord-010027-r0tl01kq	1524	13	complex	complex	NN
cord-010027-r0tl01kq	1524	14	,	,	,
cord-010027-r0tl01kq	1524	15	has	have	VBZ
cord-010027-r0tl01kq	1524	16	also	also	RB
cord-010027-r0tl01kq	1524	17	been	be	VBN
cord-010027-r0tl01kq	1524	18	linked	link	VBN
cord-010027-r0tl01kq	1524	19	with	with	IN
cord-010027-r0tl01kq	1524	20	paclitaxel	paclitaxel	JJ
cord-010027-r0tl01kq	1524	21	resistance	resistance	NN
cord-010027-r0tl01kq	1524	22	.	.	.
cord-010027-r0tl01kq	1525	1	Both	both	DT
cord-010027-r0tl01kq	1525	2	markers	marker	NNS
cord-010027-r0tl01kq	1525	3	have	have	VBP
cord-010027-r0tl01kq	1525	4	individually	individually	RB
cord-010027-r0tl01kq	1525	5	been	be	VBN
cord-010027-r0tl01kq	1525	6	shown	show	VBN
cord-010027-r0tl01kq	1525	7	to	to	TO
cord-010027-r0tl01kq	1525	8	be	be	VB
cord-010027-r0tl01kq	1525	9	associated	associate	VBN
cord-010027-r0tl01kq	1525	10	with	with	IN
cord-010027-r0tl01kq	1525	11	poor	poor	JJ
cord-010027-r0tl01kq	1525	12	outcome	outcome	NN
cord-010027-r0tl01kq	1525	13	in	in	IN
cord-010027-r0tl01kq	1525	14	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1525	15	cancer	cancer	NN
cord-010027-r0tl01kq	1525	16	.	.	.
cord-010027-r0tl01kq	1526	1	High	high	JJ
cord-010027-r0tl01kq	1526	2	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1526	3	and	and	CC
cord-010027-r0tl01kq	1526	4	low	low	JJ
cord-010027-r0tl01kq	1526	5	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1526	6	immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	1526	7	staining	staining	NN
cord-010027-r0tl01kq	1526	8	is	be	VBZ
cord-010027-r0tl01kq	1526	9	associated	associate	VBN
cord-010027-r0tl01kq	1526	10	with	with	IN
cord-010027-r0tl01kq	1526	11	reduced	reduce	VBN
cord-010027-r0tl01kq	1526	12	progression	progression	NN
cord-010027-r0tl01kq	1526	13	free	free	JJ
cord-010027-r0tl01kq	1526	14	survival	survival	NN
cord-010027-r0tl01kq	1526	15	.	.	.
cord-010027-r0tl01kq	1527	1	The	the	DT
cord-010027-r0tl01kq	1527	2	main	main	JJ
cord-010027-r0tl01kq	1527	3	objective	objective	NN
cord-010027-r0tl01kq	1527	4	of	of	IN
cord-010027-r0tl01kq	1527	5	this	this	DT
cord-010027-r0tl01kq	1527	6	study	study	NN
cord-010027-r0tl01kq	1527	7	was	be	VBD
cord-010027-r0tl01kq	1527	8	to	to	TO
cord-010027-r0tl01kq	1527	9	assess	assess	VB
cord-010027-r0tl01kq	1527	10	the	the	DT
cord-010027-r0tl01kq	1527	11	combined	combined	JJ
cord-010027-r0tl01kq	1527	12	utility	utility	NN
cord-010027-r0tl01kq	1527	13	of	of	IN
cord-010027-r0tl01kq	1527	14	MAD2	MAD2	NNPS
cord-010027-r0tl01kq	1527	15	and	and	CC
cord-010027-r0tl01kq	1527	16	MyD88	MyD88	NNPS
cord-010027-r0tl01kq	1527	17	in	in	IN
cord-010027-r0tl01kq	1527	18	predicting	predict	VBG
cord-010027-r0tl01kq	1527	19	patient	patient	JJ
cord-010027-r0tl01kq	1527	20	prognosis	prognosis	NN
cord-010027-r0tl01kq	1527	21	.	.	.
cord-010027-r0tl01kq	1528	1	Methods	method	NNS
cord-010027-r0tl01kq	1528	2	:	:	:
cord-010027-r0tl01kq	1528	3	Two	two	CD
cord-010027-r0tl01kq	1528	4	tissue	tissue	NN
cord-010027-r0tl01kq	1528	5	microarrays	microarray	NNS
cord-010027-r0tl01kq	1528	6	composed	compose	VBN
cord-010027-r0tl01kq	1528	7	of	of	IN
cord-010027-r0tl01kq	1528	8	cores	core	NNS
cord-010027-r0tl01kq	1528	9	from	from	IN
cord-010027-r0tl01kq	1528	10	51	51	CD
cord-010027-r0tl01kq	1528	11	high	high	JJ
cord-010027-r0tl01kq	1528	12	grade	grade	NN
cord-010027-r0tl01kq	1528	13	serous	serous	JJ
cord-010027-r0tl01kq	1528	14	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1528	15	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1528	16	cancers	cancer	NNS
cord-010027-r0tl01kq	1528	17	patients	patient	NNS
cord-010027-r0tl01kq	1528	18	were	be	VBD
cord-010027-r0tl01kq	1528	19	constructed	construct	VBN
cord-010027-r0tl01kq	1528	20	and	and	CC
cord-010027-r0tl01kq	1528	21	stained	stain	VBN
cord-010027-r0tl01kq	1528	22	for	for	IN
cord-010027-r0tl01kq	1528	23	MAD2	MAD2	NNPS
cord-010027-r0tl01kq	1528	24	and	and	CC
cord-010027-r0tl01kq	1528	25	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1528	26	.	.	.
cord-010027-r0tl01kq	1529	1	Staining	stain	VBG
cord-010027-r0tl01kq	1529	2	was	be	VBD
cord-010027-r0tl01kq	1529	3	scored	score	VBN
cord-010027-r0tl01kq	1529	4	based	base	VBN
cord-010027-r0tl01kq	1529	5	on	on	IN
cord-010027-r0tl01kq	1529	6	previously	previously	RB
cord-010027-r0tl01kq	1529	7	derived	derive	VBN
cord-010027-r0tl01kq	1529	8	scoring	scoring	NN
cord-010027-r0tl01kq	1529	9	schemes	scheme	NNS
cord-010027-r0tl01kq	1529	10	for	for	IN
cord-010027-r0tl01kq	1529	11	MyD88	MyD88	NNS
cord-010027-r0tl01kq	1529	12	or	or	CC
cord-010027-r0tl01kq	1529	13	MAD2	MAD2	NNP
cord-010027-r0tl01kq	1529	14	staining	staining	NN
cord-010027-r0tl01kq	1529	15	.	.	.
cord-010027-r0tl01kq	1530	1	The	the	DT
cord-010027-r0tl01kq	1530	2	mean	mean	JJ
cord-010027-r0tl01kq	1530	3	overall	overall	JJ
cord-010027-r0tl01kq	1530	4	score	score	NN
cord-010027-r0tl01kq	1530	5	from	from	IN
cord-010027-r0tl01kq	1530	6	triplicate	triplicate	NN
cord-010027-r0tl01kq	1530	7	cores	core	NNS
cord-010027-r0tl01kq	1530	8	was	be	VBD
cord-010027-r0tl01kq	1530	9	then	then	RB
cord-010027-r0tl01kq	1530	10	used	use	VBN
cord-010027-r0tl01kq	1530	11	to	to	TO
cord-010027-r0tl01kq	1530	12	classify	classify	VB
cord-010027-r0tl01kq	1530	13	patients	patient	NNS
cord-010027-r0tl01kq	1530	14	into	into	IN
cord-010027-r0tl01kq	1530	15	high	high	JJ
cord-010027-r0tl01kq	1530	16	and	and	CC
cord-010027-r0tl01kq	1530	17	low	low	JJ
cord-010027-r0tl01kq	1530	18	staining	staining	NN
cord-010027-r0tl01kq	1530	19	categories	category	NNS
cord-010027-r0tl01kq	1530	20	.	.	.
cord-010027-r0tl01kq	1531	1	Results	result	NNS
cord-010027-r0tl01kq	1531	2	:	:	:
cord-010027-r0tl01kq	1532	1	A	a	DT
cord-010027-r0tl01kq	1532	2	trend	trend	NN
cord-010027-r0tl01kq	1532	3	towards	towards	IN
cord-010027-r0tl01kq	1532	4	reduced	reduce	VBN
cord-010027-r0tl01kq	1532	5	progression	progression	NN
cord-010027-r0tl01kq	1532	6	free	free	JJ
cord-010027-r0tl01kq	1532	7	and	and	CC
cord-010027-r0tl01kq	1532	8	overall	overall	JJ
cord-010027-r0tl01kq	1532	9	survival	survival	NN
cord-010027-r0tl01kq	1532	10	was	be	VBD
cord-010027-r0tl01kq	1532	11	observed	observe	VBN
cord-010027-r0tl01kq	1532	12	in	in	IN
cord-010027-r0tl01kq	1532	13	patients	patient	NNS
cord-010027-r0tl01kq	1532	14	with	with	IN
cord-010027-r0tl01kq	1532	15	high	high	JJ
cord-010027-r0tl01kq	1532	16	myd88	myd88	NNS
cord-010027-r0tl01kq	1532	17	and	and	CC
cord-010027-r0tl01kq	1532	18	low	low	JJ
cord-010027-r0tl01kq	1532	19	mad2	mad2	CD
cord-010027-r0tl01kq	1532	20	expression	expression	NN
cord-010027-r0tl01kq	1532	21	.	.	.
cord-010027-r0tl01kq	1533	1	The	the	DT
cord-010027-r0tl01kq	1533	2	results	result	NNS
cord-010027-r0tl01kq	1533	3	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	1533	4	the	the	DT
cord-010027-r0tl01kq	1533	5	combined	combined	JJ
cord-010027-r0tl01kq	1533	6	utility	utility	NN
cord-010027-r0tl01kq	1533	7	of	of	IN
cord-010027-r0tl01kq	1533	8	MAD2	MAD2	NNPS
cord-010027-r0tl01kq	1533	9	and	and	CC
cord-010027-r0tl01kq	1533	10	MyD88	MyD88	NNPS
cord-010027-r0tl01kq	1533	11	as	as	IN
cord-010027-r0tl01kq	1533	12	predictors	predictor	NNS
cord-010027-r0tl01kq	1533	13	of	of	IN
cord-010027-r0tl01kq	1533	14	prognosis	prognosis	NN
cord-010027-r0tl01kq	1533	15	in	in	IN
cord-010027-r0tl01kq	1533	16	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1533	17	cancer	cancer	NN
cord-010027-r0tl01kq	1533	18	.	.	.
cord-010027-r0tl01kq	1534	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1534	2	:	:	:
cord-010027-r0tl01kq	1535	1	Ovarian	ovarian	JJ
cord-010027-r0tl01kq	1535	2	cancer	cancer	NN
cord-010027-r0tl01kq	1535	3	is	be	VBZ
cord-010027-r0tl01kq	1535	4	characterised	characterise	VBN
cord-010027-r0tl01kq	1535	5	by	by	IN
cord-010027-r0tl01kq	1535	6	high	high	JJ
cord-010027-r0tl01kq	1535	7	rates	rate	NNS
cord-010027-r0tl01kq	1535	8	of	of	IN
cord-010027-r0tl01kq	1535	9	terminal	terminal	JJ
cord-010027-r0tl01kq	1535	10	,	,	,
cord-010027-r0tl01kq	1535	11	chemoresistant	chemoresistant	JJ
cord-010027-r0tl01kq	1535	12	recurrence	recurrence	NN
cord-010027-r0tl01kq	1535	13	.	.	.
cord-010027-r0tl01kq	1536	1	Although	although	IN
cord-010027-r0tl01kq	1536	2	chemoresistance	chemoresistance	NNP
cord-010027-r0tl01kq	1536	3	is	be	VBZ
cord-010027-r0tl01kq	1536	4	known	know	VBN
cord-010027-r0tl01kq	1536	5	to	to	TO
cord-010027-r0tl01kq	1536	6	be	be	VB
cord-010027-r0tl01kq	1536	7	a	a	DT
cord-010027-r0tl01kq	1536	8	property	property	NN
cord-010027-r0tl01kq	1536	9	of	of	IN
cord-010027-r0tl01kq	1536	10	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1536	11	Stem	Stem	NNP
cord-010027-r0tl01kq	1536	12	Cells	cell	NNS
cord-010027-r0tl01kq	1536	13	(	(	-LRB-
cord-010027-r0tl01kq	1536	14	CSCs	CSCs	NNP
cord-010027-r0tl01kq	1536	15	)	)	-RRB-
cord-010027-r0tl01kq	1536	16	,	,	,
cord-010027-r0tl01kq	1536	17	the	the	DT
cord-010027-r0tl01kq	1536	18	mechanism	mechanism	NN
cord-010027-r0tl01kq	1536	19	is	be	VBZ
cord-010027-r0tl01kq	1536	20	poorly	poorly	RB
cord-010027-r0tl01kq	1536	21	understood	understand	VBN
cord-010027-r0tl01kq	1536	22	.	.	.
cord-010027-r0tl01kq	1537	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1537	2	have	have	VBP
cord-010027-r0tl01kq	1537	3	previously	previously	RB
cord-010027-r0tl01kq	1537	4	identified	identify	VBN
cord-010027-r0tl01kq	1537	5	a	a	DT
cord-010027-r0tl01kq	1537	6	novel	novel	JJ
cord-010027-r0tl01kq	1537	7	four	four	CD
cord-010027-r0tl01kq	1537	8	-	-	HYPH
cord-010027-r0tl01kq	1537	9	member	member	NN
cord-010027-r0tl01kq	1537	10	CSC	CSC	NNP
cord-010027-r0tl01kq	1537	11	Stem	Stem	NNP
cord-010027-r0tl01kq	1537	12	-	-	HYPH
cord-010027-r0tl01kq	1537	13	Progenitor	Progenitor	NNP
cord-010027-r0tl01kq	1537	14	cell	cell	NN
cord-010027-r0tl01kq	1537	15	hierarchy	hierarchy	NN
cord-010027-r0tl01kq	1537	16	for	for	IN
cord-010027-r0tl01kq	1537	17	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1537	18	cancer	cancer	NN
cord-010027-r0tl01kq	1537	19	.	.	.
cord-010027-r0tl01kq	1538	1	The	the	DT
cord-010027-r0tl01kq	1538	2	aim	aim	NN
cord-010027-r0tl01kq	1538	3	of	of	IN
cord-010027-r0tl01kq	1538	4	this	this	DT
cord-010027-r0tl01kq	1538	5	study	study	NN
cord-010027-r0tl01kq	1538	6	was	be	VBD
cord-010027-r0tl01kq	1538	7	to	to	TO
cord-010027-r0tl01kq	1538	8	characterise	characterise	VB
cord-010027-r0tl01kq	1538	9	the	the	DT
cord-010027-r0tl01kq	1538	10	contribution	contribution	NN
cord-010027-r0tl01kq	1538	11	of	of	IN
cord-010027-r0tl01kq	1538	12	each	each	DT
cord-010027-r0tl01kq	1538	13	member	member	NN
cord-010027-r0tl01kq	1538	14	of	of	IN
cord-010027-r0tl01kq	1538	15	the	the	DT
cord-010027-r0tl01kq	1538	16	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1538	17	CSC	CSC	NNP
cord-010027-r0tl01kq	1538	18	hierarchy	hierarchy	NN
cord-010027-r0tl01kq	1538	19	to	to	IN
cord-010027-r0tl01kq	1538	20	chemoresistance	chemoresistance	NNP
cord-010027-r0tl01kq	1538	21	.	.	.
cord-010027-r0tl01kq	1539	1	Methods	method	NNS
cord-010027-r0tl01kq	1539	2	:	:	:
cord-010027-r0tl01kq	1539	3	The	the	DT
cord-010027-r0tl01kq	1539	4	CSC	CSC	NNP
cord-010027-r0tl01kq	1539	5	hierarchy	hierarchy	NN
cord-010027-r0tl01kq	1539	6	was	be	VBD
cord-010027-r0tl01kq	1539	7	assessed	assess	VBN
cord-010027-r0tl01kq	1539	8	for	for	IN
cord-010027-r0tl01kq	1539	9	tolerance	tolerance	NN
cord-010027-r0tl01kq	1539	10	to	to	IN
cord-010027-r0tl01kq	1539	11	chemotherapy	chemotherapy	NN
cord-010027-r0tl01kq	1539	12	drug	drug	NN
cord-010027-r0tl01kq	1539	13	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	1539	14	(	(	-LRB-
cord-010027-r0tl01kq	1539	15	MTT	MTT	NNP
cord-010027-r0tl01kq	1539	16	assay	assay	NN
cord-010027-r0tl01kq	1539	17	)	)	-RRB-
cord-010027-r0tl01kq	1539	18	both	both	CC
cord-010027-r0tl01kq	1539	19	as	as	IN
cord-010027-r0tl01kq	1539	20	components	component	NNS
cord-010027-r0tl01kq	1539	21	of	of	IN
cord-010027-r0tl01kq	1539	22	the	the	DT
cord-010027-r0tl01kq	1539	23	parent	parent	NN
cord-010027-r0tl01kq	1539	24	population	population	NN
cord-010027-r0tl01kq	1539	25	(	(	-LRB-
cord-010027-r0tl01kq	1539	26	A2780	A2780	NNP
cord-010027-r0tl01kq	1539	27	cell	cell	NN
cord-010027-r0tl01kq	1539	28	line	line	NN
cord-010027-r0tl01kq	1539	29	)	)	-RRB-
cord-010027-r0tl01kq	1539	30	and	and	CC
cord-010027-r0tl01kq	1539	31	as	as	IN
cord-010027-r0tl01kq	1539	32	isolated	isolate	VBN
cord-010027-r0tl01kq	1539	33	cell	cell	NN
cord-010027-r0tl01kq	1539	34	types	type	NNS
cord-010027-r0tl01kq	1539	35	.	.	.
cord-010027-r0tl01kq	1540	1	The	the	DT
cord-010027-r0tl01kq	1540	2	hierarchy	hierarchy	NN
cord-010027-r0tl01kq	1540	3	was	be	VBD
cord-010027-r0tl01kq	1540	4	additionally	additionally	RB
cord-010027-r0tl01kq	1540	5	assessed	assess	VBN
cord-010027-r0tl01kq	1540	6	in	in	IN
cord-010027-r0tl01kq	1540	7	the	the	DT
cord-010027-r0tl01kq	1540	8	long	long	JJ
cord-010027-r0tl01kq	1540	9	-	-	HYPH
cord-010027-r0tl01kq	1540	10	term	term	NN
cord-010027-r0tl01kq	1540	11	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	1540	12	-	-	HYPH
cord-010027-r0tl01kq	1540	13	adapted	adapt	VBN
cord-010027-r0tl01kq	1540	14	'	'	``
cord-010027-r0tl01kq	1540	15	A2780cis	a2780cis	NN
cord-010027-r0tl01kq	1540	16	'	'	POS
cord-010027-r0tl01kq	1540	17	cell	cell	NN
cord-010027-r0tl01kq	1540	18	line	line	NN
cord-010027-r0tl01kq	1540	19	.	.	.
cord-010027-r0tl01kq	1541	1	Cell	cell	NN
cord-010027-r0tl01kq	1541	2	types	type	NNS
cord-010027-r0tl01kq	1541	3	were	be	VBD
cord-010027-r0tl01kq	1541	4	analysed	analyse	VBN
cord-010027-r0tl01kq	1541	5	and	and	CC
cord-010027-r0tl01kq	1541	6	isolated	isolate	VBN
cord-010027-r0tl01kq	1541	7	via	via	IN
cord-010027-r0tl01kq	1541	8	flow	flow	NN
cord-010027-r0tl01kq	1541	9	cytometry	cytometry	NN
cord-010027-r0tl01kq	1541	10	and	and	CC
cord-010027-r0tl01kq	1541	11	assessed	assess	VBN
cord-010027-r0tl01kq	1541	12	for	for	IN
cord-010027-r0tl01kq	1541	13	stem	stem	NN
cord-010027-r0tl01kq	1541	14	cell	cell	NN
cord-010027-r0tl01kq	1541	15	characteristic	characteristic	NN
cord-010027-r0tl01kq	1541	16	via	via	IN
cord-010027-r0tl01kq	1541	17	single	single	JJ
cord-010027-r0tl01kq	1541	18	-	-	HYPH
cord-010027-r0tl01kq	1541	19	cell	cell	NN
cord-010027-r0tl01kq	1541	20	asymmetric	asymmetric	JJ
cord-010027-r0tl01kq	1541	21	division	division	NN
cord-010027-r0tl01kq	1541	22	and	and	CC
cord-010027-r0tl01kq	1541	23	murine	murine	JJ
cord-010027-r0tl01kq	1541	24	xenograft	xenograft	NN
cord-010027-r0tl01kq	1541	25	tumourigenicity	tumourigenicity	NN
cord-010027-r0tl01kq	1541	26	assays	assay	NNS
cord-010027-r0tl01kq	1541	27	,	,	,
cord-010027-r0tl01kq	1541	28	and	and	CC
cord-010027-r0tl01kq	1541	29	molecularly	molecularly	RB
cord-010027-r0tl01kq	1541	30	characterised	characterise	VBN
cord-010027-r0tl01kq	1541	31	(	(	-LRB-
cord-010027-r0tl01kq	1541	32	whole	whole	JJ
cord-010027-r0tl01kq	1541	33	transcriptome	transcriptome	NN
cord-010027-r0tl01kq	1541	34	arrays	array	NNS
cord-010027-r0tl01kq	1541	35	)	)	-RRB-
cord-010027-r0tl01kq	1541	36	.	.	.
cord-010027-r0tl01kq	1542	1	Results	result	NNS
cord-010027-r0tl01kq	1542	2	:	:	:
cord-010027-r0tl01kq	1543	1	Cisplain	Cisplain	NNP
cord-010027-r0tl01kq	1543	2	dose	dose	NN
cord-010027-r0tl01kq	1543	3	-	-	HYPH
cord-010027-r0tl01kq	1543	4	response	response	NN
cord-010027-r0tl01kq	1543	5	assays	assay	NNS
cord-010027-r0tl01kq	1543	6	from	from	IN
cord-010027-r0tl01kq	1543	7	A2780-derived	A2780-derived	NNP
cord-010027-r0tl01kq	1543	8	CSC	CSC	NNP
cord-010027-r0tl01kq	1543	9	sub	sub	NN
cord-010027-r0tl01kq	1543	10	-	-	HYPH
cord-010027-r0tl01kq	1543	11	populations	population	NNS
cord-010027-r0tl01kq	1543	12	indicated	indicate	VBD
cord-010027-r0tl01kq	1543	13	that	that	IN
cord-010027-r0tl01kq	1543	14	only	only	RB
cord-010027-r0tl01kq	1543	15	one	one	CD
cord-010027-r0tl01kq	1543	16	of	of	IN
cord-010027-r0tl01kq	1543	17	the	the	DT
cord-010027-r0tl01kq	1543	18	four	four	CD
cord-010027-r0tl01kq	1543	19	populations	population	NNS
cord-010027-r0tl01kq	1543	20	within	within	IN
cord-010027-r0tl01kq	1543	21	the	the	DT
cord-010027-r0tl01kq	1543	22	hierarchy	hierarchy	NN
cord-010027-r0tl01kq	1543	23	had	have	VBD
cord-010027-r0tl01kq	1543	24	a	a	DT
cord-010027-r0tl01kq	1543	25	high	high	JJ
cord-010027-r0tl01kq	1543	26	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	1543	27	-	-	HYPH
cord-010027-r0tl01kq	1543	28	tolerance	tolerance	NN
cord-010027-r0tl01kq	1543	29	(	(	-LRB-
cord-010027-r0tl01kq	1543	30	IC50=10uM	IC50=10uM	NNP
cord-010027-r0tl01kq	1543	31	)	)	-RRB-
cord-010027-r0tl01kq	1543	32	compared	compare	VBN
cord-010027-r0tl01kq	1543	33	to	to	IN
cord-010027-r0tl01kq	1543	34	the	the	DT
cord-010027-r0tl01kq	1543	35	other	other	JJ
cord-010027-r0tl01kq	1543	36	populations	population	NNS
cord-010027-r0tl01kq	1543	37	(	(	-LRB-
cord-010027-r0tl01kq	1543	38	IC50=4uM	IC50=4uM	NNP
cord-010027-r0tl01kq	1543	39	)	)	-RRB-
cord-010027-r0tl01kq	1543	40	.	.	.
cord-010027-r0tl01kq	1544	1	This	this	DT
cord-010027-r0tl01kq	1544	2	was	be	VBD
cord-010027-r0tl01kq	1544	3	notable	notable	JJ
cord-010027-r0tl01kq	1544	4	as	as	IN
cord-010027-r0tl01kq	1544	5	the	the	DT
cord-010027-r0tl01kq	1544	6	relative	relative	JJ
cord-010027-r0tl01kq	1544	7	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	1544	8	IC50s	IC50s	NNP
cord-010027-r0tl01kq	1544	9	for	for	IN
cord-010027-r0tl01kq	1544	10	the	the	DT
cord-010027-r0tl01kq	1544	11	A2780	A2780	NNP
cord-010027-r0tl01kq	1544	12	and	and	CC
cord-010027-r0tl01kq	1544	13	A2780cis	A2780cis	NNP
cord-010027-r0tl01kq	1544	14	parent	parent	NN
cord-010027-r0tl01kq	1544	15	cell	cell	NN
cord-010027-r0tl01kq	1544	16	lines	line	NNS
cord-010027-r0tl01kq	1544	17	are	be	VBP
cord-010027-r0tl01kq	1544	18	4uM	4um	CD
cord-010027-r0tl01kq	1544	19	and	and	CC
cord-010027-r0tl01kq	1544	20	11uM	11um	CD
cord-010027-r0tl01kq	1544	21	respectively	respectively	RB
cord-010027-r0tl01kq	1544	22	.	.	.
cord-010027-r0tl01kq	1545	1	Treatment	treatment	NN
cord-010027-r0tl01kq	1545	2	of	of	IN
cord-010027-r0tl01kq	1545	3	the	the	DT
cord-010027-r0tl01kq	1545	4	parent	parent	NN
cord-010027-r0tl01kq	1545	5	A2780	A2780	NNP
cord-010027-r0tl01kq	1545	6	cell	cell	NN
cord-010027-r0tl01kq	1545	7	line	line	NN
cord-010027-r0tl01kq	1545	8	with	with	IN
cord-010027-r0tl01kq	1545	9	the	the	DT
cord-010027-r0tl01kq	1545	10	IC50	IC50	NNP
cord-010027-r0tl01kq	1545	11	(	(	-LRB-
cord-010027-r0tl01kq	1545	12	48	48	CD
cord-010027-r0tl01kq	1545	13	hours	hour	NNS
cord-010027-r0tl01kq	1545	14	)	)	-RRB-
cord-010027-r0tl01kq	1545	15	resulted	result	VBD
cord-010027-r0tl01kq	1545	16	in	in	IN
cord-010027-r0tl01kq	1545	17	a	a	DT
cord-010027-r0tl01kq	1545	18	proportional	proportional	JJ
cord-010027-r0tl01kq	1545	19	50	50	CD
cord-010027-r0tl01kq	1545	20	%	%	NN
cord-010027-r0tl01kq	1545	21	loss	loss	NN
cord-010027-r0tl01kq	1545	22	in	in	IN
cord-010027-r0tl01kq	1545	23	each	each	DT
cord-010027-r0tl01kq	1545	24	of	of	IN
cord-010027-r0tl01kq	1545	25	the	the	DT
cord-010027-r0tl01kq	1545	26	four	four	CD
cord-010027-r0tl01kq	1545	27	cell	cell	NN
cord-010027-r0tl01kq	1545	28	types	type	NNS
cord-010027-r0tl01kq	1545	29	,	,	,
cord-010027-r0tl01kq	1545	30	suggesting	suggest	VBG
cord-010027-r0tl01kq	1545	31	that	that	IN
cord-010027-r0tl01kq	1545	32	this	this	DT
cord-010027-r0tl01kq	1545	33	specific	specific	JJ
cord-010027-r0tl01kq	1545	34	CSC	CSC	NNP
cord-010027-r0tl01kq	1545	35	subpopulation	subpopulation	NN
cord-010027-r0tl01kq	1545	36	adapts	adapt	VBZ
cord-010027-r0tl01kq	1545	37	to	to	IN
cord-010027-r0tl01kq	1545	38	cisplatin	cisplatin	NN
cord-010027-r0tl01kq	1545	39	over	over	IN
cord-010027-r0tl01kq	1545	40	a	a	DT
cord-010027-r0tl01kq	1545	41	longer	long	JJR
cord-010027-r0tl01kq	1545	42	period	period	NN
cord-010027-r0tl01kq	1545	43	of	of	IN
cord-010027-r0tl01kq	1545	44	time	time	NN
cord-010027-r0tl01kq	1545	45	.	.	.
cord-010027-r0tl01kq	1546	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1546	2	:	:	:
cord-010027-r0tl01kq	1547	1	Although	although	IN
cord-010027-r0tl01kq	1547	2	CSCs	csc	NNS
cord-010027-r0tl01kq	1547	3	are	be	VBP
cord-010027-r0tl01kq	1547	4	known	know	VBN
cord-010027-r0tl01kq	1547	5	to	to	TO
cord-010027-r0tl01kq	1547	6	be	be	VB
cord-010027-r0tl01kq	1547	7	chemoresistant	chemoresistant	JJ
cord-010027-r0tl01kq	1547	8	,	,	,
cord-010027-r0tl01kq	1547	9	the	the	DT
cord-010027-r0tl01kq	1547	10	mechanism	mechanism	NN
cord-010027-r0tl01kq	1547	11	though	though	IN
cord-010027-r0tl01kq	1547	12	which	which	WDT
cord-010027-r0tl01kq	1547	13	this	this	DT
cord-010027-r0tl01kq	1547	14	is	be	VBZ
cord-010027-r0tl01kq	1547	15	achieved	achieve	VBN
cord-010027-r0tl01kq	1547	16	is	be	VBZ
cord-010027-r0tl01kq	1547	17	poorly	poorly	RB
cord-010027-r0tl01kq	1547	18	understood	understand	VBN
cord-010027-r0tl01kq	1547	19	.	.	.
cord-010027-r0tl01kq	1548	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1548	2	data	data	NN
cord-010027-r0tl01kq	1548	3	indicates	indicate	VBZ
cord-010027-r0tl01kq	1548	4	that	that	IN
cord-010027-r0tl01kq	1548	5	only	only	RB
cord-010027-r0tl01kq	1548	6	some	some	DT
cord-010027-r0tl01kq	1548	7	members	member	NNS
cord-010027-r0tl01kq	1548	8	of	of	IN
cord-010027-r0tl01kq	1548	9	a	a	DT
cord-010027-r0tl01kq	1548	10	CSC	CSC	NNP
cord-010027-r0tl01kq	1548	11	hierarchy	hierarchy	NN
cord-010027-r0tl01kq	1548	12	are	be	VBP
cord-010027-r0tl01kq	1548	13	responsible	responsible	JJ
cord-010027-r0tl01kq	1548	14	for	for	IN
cord-010027-r0tl01kq	1548	15	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	1548	16	.	.	.
cord-010027-r0tl01kq	1549	1	Notably	notably	RB
cord-010027-r0tl01kq	1549	2	,	,	,
cord-010027-r0tl01kq	1549	3	this	this	DT
cord-010027-r0tl01kq	1549	4	sub	sub	NN
cord-010027-r0tl01kq	1549	5	-	-	JJ
cord-010027-r0tl01kq	1549	6	population	population	NN
cord-010027-r0tl01kq	1549	7	appears	appear	VBZ
cord-010027-r0tl01kq	1549	8	to	to	TO
cord-010027-r0tl01kq	1549	9	possess	possess	VB
cord-010027-r0tl01kq	1549	10	inherent	inherent	JJ
cord-010027-r0tl01kq	1549	11	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	1549	12	in	in	IN
cord-010027-r0tl01kq	1549	13	pre	pre	NNP
cord-010027-r0tl01kq	1549	14	-	-	JJ
cord-010027-r0tl01kq	1549	15	treatmentcells	treatmentcells	NNP
cord-010027-r0tl01kq	1549	16	.	.	.
cord-010027-r0tl01kq	1550	1	As	as	IN
cord-010027-r0tl01kq	1550	2	such	such	JJ
cord-010027-r0tl01kq	1550	3	,	,	,
cord-010027-r0tl01kq	1550	4	it	-PRON-	PRP
cord-010027-r0tl01kq	1550	5	should	should	MD
cord-010027-r0tl01kq	1550	6	be	be	VB
cord-010027-r0tl01kq	1550	7	possible	possible	JJ
cord-010027-r0tl01kq	1550	8	to	to	TO
cord-010027-r0tl01kq	1550	9	target	target	VB
cord-010027-r0tl01kq	1550	10	these	these	DT
cord-010027-r0tl01kq	1550	11	CSCs	csc	NNS
cord-010027-r0tl01kq	1550	12	in	in	IN
cord-010027-r0tl01kq	1550	13	the	the	DT
cord-010027-r0tl01kq	1550	14	primary	primary	JJ
cord-010027-r0tl01kq	1550	15	malignancy	malignancy	NN
cord-010027-r0tl01kq	1550	16	to	to	TO
cord-010027-r0tl01kq	1550	17	prevent	prevent	VB
cord-010027-r0tl01kq	1550	18	chemoresistant	chemoresistant	JJ
cord-010027-r0tl01kq	1550	19	recurrence	recurrence	NN
cord-010027-r0tl01kq	1550	20	.	.	.
cord-010027-r0tl01kq	1551	1	Mixed	mixed	JJ
cord-010027-r0tl01kq	1551	2	sex	sex	NN
cord-010027-r0tl01kq	1551	3	cord	cord	NN
cord-010027-r0tl01kq	1551	4	-	-	HYPH
cord-010027-r0tl01kq	1551	5	stromal	stromal	NN
cord-010027-r0tl01kq	1551	6	tumours	tumour	NNS
cord-010027-r0tl01kq	1551	7	of	of	IN
cord-010027-r0tl01kq	1551	8	the	the	DT
cord-010027-r0tl01kq	1551	9	ovary	ovary	NN
cord-010027-r0tl01kq	1551	10	are	be	VBP
cord-010027-r0tl01kq	1551	11	very	very	RB
cord-010027-r0tl01kq	1551	12	rare	rare	JJ
cord-010027-r0tl01kq	1551	13	.	.	.
cord-010027-r0tl01kq	1552	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1552	2	report	report	VBP
cord-010027-r0tl01kq	1552	3	a	a	DT
cord-010027-r0tl01kq	1552	4	case	case	NN
cord-010027-r0tl01kq	1552	5	of	of	IN
cord-010027-r0tl01kq	1552	6	mixed	mixed	JJ
cord-010027-r0tl01kq	1552	7	sex	sex	NN
cord-010027-r0tl01kq	1552	8	cord	cord	NN
cord-010027-r0tl01kq	1552	9	-stromal	-stromal	JJ
cord-010027-r0tl01kq	1552	10	tumour	tumour	NN
cord-010027-r0tl01kq	1552	11	(	(	-LRB-
cord-010027-r0tl01kq	1552	12	also	also	RB
cord-010027-r0tl01kq	1552	13	referred	refer	VBN
cord-010027-r0tl01kq	1552	14	to	to	IN
cord-010027-r0tl01kq	1552	15	as	as	IN
cord-010027-r0tl01kq	1552	16	gynandroblastoma	gynandroblastoma	NNP
cord-010027-r0tl01kq	1552	17	)	)	-RRB-
cord-010027-r0tl01kq	1552	18	containing	contain	VBG
cord-010027-r0tl01kq	1552	19	both	both	DT
cord-010027-r0tl01kq	1552	20	Sertoli	Sertoli	NNP
cord-010027-r0tl01kq	1552	21	-	-	HYPH
cord-010027-r0tl01kq	1552	22	Leydig	leydig	NN
cord-010027-r0tl01kq	1552	23	cell	cell	NN
cord-010027-r0tl01kq	1552	24	tumour	tumour	NN
cord-010027-r0tl01kq	1552	25	and	and	CC
cord-010027-r0tl01kq	1552	26	adult	adult	NN
cord-010027-r0tl01kq	1552	27	granulosa	granulosa	JJ
cord-010027-r0tl01kq	1552	28	cell	cell	NN
cord-010027-r0tl01kq	1552	29	tumour	tumour	NN
cord-010027-r0tl01kq	1552	30	in	in	IN
cord-010027-r0tl01kq	1552	31	a	a	DT
cord-010027-r0tl01kq	1552	32	female	female	JJ
cord-010027-r0tl01kq	1552	33	61	61	CD
cord-010027-r0tl01kq	1552	34	years	year	NNS
cord-010027-r0tl01kq	1552	35	old	old	JJ
cord-010027-r0tl01kq	1552	36	who	who	WP
cord-010027-r0tl01kq	1552	37	presented	present	VBD
cord-010027-r0tl01kq	1552	38	with	with	IN
cord-010027-r0tl01kq	1552	39	postmenopausal	postmenopausal	JJ
cord-010027-r0tl01kq	1552	40	bleeding	bleed	VBG
cord-010027-r0tl01kq	1552	41	.	.	.
cord-010027-r0tl01kq	1553	1	On	on	IN
cord-010027-r0tl01kq	1553	2	histology	histology	NN
cord-010027-r0tl01kq	1553	3	,	,	,
cord-010027-r0tl01kq	1553	4	the	the	DT
cord-010027-r0tl01kq	1553	5	majority	majority	NN
cord-010027-r0tl01kq	1553	6	of	of	IN
cord-010027-r0tl01kq	1553	7	the	the	DT
cord-010027-r0tl01kq	1553	8	tumour	tumour	NN
cord-010027-r0tl01kq	1553	9	represented	represent	VBD
cord-010027-r0tl01kq	1553	10	an	an	DT
cord-010027-r0tl01kq	1553	11	unsual	unsual	JJ
cord-010027-r0tl01kq	1553	12	form	form	NN
cord-010027-r0tl01kq	1553	13	of	of	IN
cord-010027-r0tl01kq	1553	14	well	well	RB
cord-010027-r0tl01kq	1553	15	differentiated	differentiate	VBN
cord-010027-r0tl01kq	1553	16	Sertoli	Sertoli	NNP
cord-010027-r0tl01kq	1553	17	-	-	HYPH
cord-010027-r0tl01kq	1553	18	Leydig	leydig	NN
cord-010027-r0tl01kq	1553	19	cell	cell	NN
cord-010027-r0tl01kq	1553	20	tumour	tumour	NN
cord-010027-r0tl01kq	1553	21	with	with	IN
cord-010027-r0tl01kq	1553	22	a	a	DT
cord-010027-r0tl01kq	1553	23	pseudoendometrioid	pseudoendometrioid	JJ
cord-010027-r0tl01kq	1553	24	appearance	appearance	NN
cord-010027-r0tl01kq	1553	25	.	.	.
cord-010027-r0tl01kq	1554	1	Minor	minor	JJ
cord-010027-r0tl01kq	1554	2	foci	focus	NNS
cord-010027-r0tl01kq	1554	3	of	of	IN
cord-010027-r0tl01kq	1554	4	classic	classic	JJ
cord-010027-r0tl01kq	1554	5	adult	adult	NN
cord-010027-r0tl01kq	1554	6	granulosa	granulosa	JJ
cord-010027-r0tl01kq	1554	7	cell	cell	NN
cord-010027-r0tl01kq	1554	8	tumour	tumour	NN
cord-010027-r0tl01kq	1554	9	were	be	VBD
cord-010027-r0tl01kq	1554	10	present	present	JJ
cord-010027-r0tl01kq	1554	11	.	.	.
cord-010027-r0tl01kq	1555	1	On	on	IN
cord-010027-r0tl01kq	1555	2	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1555	3	,	,	,
cord-010027-r0tl01kq	1555	4	the	the	DT
cord-010027-r0tl01kq	1555	5	tumour	tumour	NN
cord-010027-r0tl01kq	1555	6	was	be	VBD
cord-010027-r0tl01kq	1555	7	diffusely	diffusely	RB
cord-010027-r0tl01kq	1555	8	positive	positive	JJ
cord-010027-r0tl01kq	1555	9	for	for	IN
cord-010027-r0tl01kq	1555	10	inhibin	inhibin	NNP
cord-010027-r0tl01kq	1555	11	and	and	CC
cord-010027-r0tl01kq	1555	12	SF1	SF1	NNP
cord-010027-r0tl01kq	1555	13	and	and	CC
cord-010027-r0tl01kq	1555	14	focally	focally	RB
cord-010027-r0tl01kq	1555	15	for	for	IN
cord-010027-r0tl01kq	1555	16	calretinin	calretinin	NNS
cord-010027-r0tl01kq	1555	17	,	,	,
cord-010027-r0tl01kq	1555	18	ER	ER	NNP
cord-010027-r0tl01kq	1555	19	and	and	CC
cord-010027-r0tl01kq	1555	20	CD56	CD56	NNP
cord-010027-r0tl01kq	1555	21	.	.	.
cord-010027-r0tl01kq	1556	1	EMA	EMA	NNP
cord-010027-r0tl01kq	1556	2	,	,	,
cord-010027-r0tl01kq	1556	3	PAX8	PAX8	NNP
cord-010027-r0tl01kq	1556	4	and	and	CC
cord-010027-r0tl01kq	1556	5	CK7	CK7	NNP
cord-010027-r0tl01kq	1556	6	were	be	VBD
cord-010027-r0tl01kq	1556	7	negative	negative	JJ
cord-010027-r0tl01kq	1556	8	.	.	.
cord-010027-r0tl01kq	1557	1	As	as	RB
cord-010027-r0tl01kq	1557	2	far	far	RB
cord-010027-r0tl01kq	1557	3	as	as	IN
cord-010027-r0tl01kq	1557	4	we	-PRON-	PRP
cord-010027-r0tl01kq	1557	5	are	be	VBP
cord-010027-r0tl01kq	1557	6	aware	aware	JJ
cord-010027-r0tl01kq	1557	7	,	,	,
cord-010027-r0tl01kq	1557	8	this	this	DT
cord-010027-r0tl01kq	1557	9	is	be	VBZ
cord-010027-r0tl01kq	1557	10	the	the	DT
cord-010027-r0tl01kq	1557	11	first	first	JJ
cord-010027-r0tl01kq	1557	12	report	report	NN
cord-010027-r0tl01kq	1557	13	of	of	IN
cord-010027-r0tl01kq	1557	14	an	an	DT
cord-010027-r0tl01kq	1557	15	ovarian	ovarian	JJ
cord-010027-r0tl01kq	1557	16	mixed	mixed	JJ
cord-010027-r0tl01kq	1557	17	sex	sex	NN
cord-010027-r0tl01kq	1557	18	cord	cord	NN
cord-010027-r0tl01kq	1557	19	-	-	HYPH
cord-010027-r0tl01kq	1557	20	stromal	stromal	NN
cord-010027-r0tl01kq	1557	21	tumour	tumour	NN
cord-010027-r0tl01kq	1557	22	containing	contain	VBG
cord-010027-r0tl01kq	1557	23	a	a	DT
cord-010027-r0tl01kq	1557	24	component	component	NN
cord-010027-r0tl01kq	1557	25	of	of	IN
cord-010027-r0tl01kq	1557	26	pseudoendometrioid	pseudoendometrioid	NNP
cord-010027-r0tl01kq	1557	27	Sertoli	Sertoli	NNP
cord-010027-r0tl01kq	1557	28	-	-	HYPH
cord-010027-r0tl01kq	1557	29	Leydig	leydig	NN
cord-010027-r0tl01kq	1557	30	cell	cell	NN
cord-010027-r0tl01kq	1557	31	tumour	tumour	NN
cord-010027-r0tl01kq	1557	32	.	.	.
cord-010027-r0tl01kq	1558	1	A	a	DT
cord-010027-r0tl01kq	1558	2	37	37	CD
cord-010027-r0tl01kq	1558	3	year	year	NN
cord-010027-r0tl01kq	1558	4	old	old	JJ
cord-010027-r0tl01kq	1558	5	female	female	JJ
cord-010027-r0tl01kq	1558	6	patient	patient	NN
cord-010027-r0tl01kq	1558	7	presented	present	VBN
cord-010027-r0tl01kq	1558	8	with	with	IN
cord-010027-r0tl01kq	1558	9	bilateral	bilateral	JJ
cord-010027-r0tl01kq	1558	10	painful	painful	JJ
cord-010027-r0tl01kq	1558	11	warty	warty	JJ
cord-010027-r0tl01kq	1558	12	lesions	lesion	NNS
cord-010027-r0tl01kq	1558	13	on	on	IN
cord-010027-r0tl01kq	1558	14	the	the	DT
cord-010027-r0tl01kq	1558	15	labia	labium	NNS
cord-010027-r0tl01kq	1558	16	majora	majora	NNP
cord-010027-r0tl01kq	1558	17	.	.	.
cord-010027-r0tl01kq	1559	1	The	the	DT
cord-010027-r0tl01kq	1559	2	patient	patient	NN
cord-010027-r0tl01kq	1559	3	had	have	VBD
cord-010027-r0tl01kq	1559	4	had	have	VBN
cord-010027-r0tl01kq	1559	5	HIV	HIV	NNP
cord-010027-r0tl01kq	1559	6	for	for	IN
cord-010027-r0tl01kq	1559	7	a	a	DT
cord-010027-r0tl01kq	1559	8	long	long	JJ
cord-010027-r0tl01kq	1559	9	time	time	NN
cord-010027-r0tl01kq	1559	10	and	and	CC
cord-010027-r0tl01kq	1559	11	was	be	VBD
cord-010027-r0tl01kq	1559	12	on	on	IN
cord-010027-r0tl01kq	1559	13	highly	highly	RB
cord-010027-r0tl01kq	1559	14	active	active	JJ
cord-010027-r0tl01kq	1559	15	antiretroviral	antiretroviral	JJ
cord-010027-r0tl01kq	1559	16	therapy	therapy	NN
cord-010027-r0tl01kq	1559	17	.	.	.
cord-010027-r0tl01kq	1560	1	She	-PRON-	PRP
cord-010027-r0tl01kq	1560	2	also	also	RB
cord-010027-r0tl01kq	1560	3	suffered	suffer	VBD
cord-010027-r0tl01kq	1560	4	chronic	chronic	JJ
cord-010027-r0tl01kq	1560	5	renal	renal	JJ
cord-010027-r0tl01kq	1560	6	failure	failure	NN
cord-010027-r0tl01kq	1560	7	requiring	require	VBG
cord-010027-r0tl01kq	1560	8	haemodialysis	haemodialysis	NNP
cord-010027-r0tl01kq	1560	9	three	three	CD
cord-010027-r0tl01kq	1560	10	times	time	NNS
cord-010027-r0tl01kq	1560	11	weekly	weekly	JJ
cord-010027-r0tl01kq	1560	12	.	.	.
cord-010027-r0tl01kq	1561	1	Clinically	clinically	RB
cord-010027-r0tl01kq	1561	2	,	,	,
cord-010027-r0tl01kq	1561	3	the	the	DT
cord-010027-r0tl01kq	1561	4	lesions	lesion	NNS
cord-010027-r0tl01kq	1561	5	were	be	VBD
cord-010027-r0tl01kq	1561	6	highly	highly	RB
cord-010027-r0tl01kq	1561	7	suspicious	suspicious	JJ
cord-010027-r0tl01kq	1561	8	of	of	IN
cord-010027-r0tl01kq	1561	9	vulval	vulval	JJ
cord-010027-r0tl01kq	1561	10	cancer	cancer	NN
cord-010027-r0tl01kq	1561	11	.	.	.
cord-010027-r0tl01kq	1562	1	The	the	DT
cord-010027-r0tl01kq	1562	2	lesions	lesion	NNS
cord-010027-r0tl01kq	1562	3	increased	increase	VBD
cord-010027-r0tl01kq	1562	4	significantly	significantly	RB
cord-010027-r0tl01kq	1562	5	in	in	IN
cord-010027-r0tl01kq	1562	6	size	size	NN
cord-010027-r0tl01kq	1562	7	over	over	IN
cord-010027-r0tl01kq	1562	8	a	a	DT
cord-010027-r0tl01kq	1562	9	short	short	JJ
cord-010027-r0tl01kq	1562	10	period	period	NN
cord-010027-r0tl01kq	1562	11	of	of	IN
cord-010027-r0tl01kq	1562	12	time	time	NN
cord-010027-r0tl01kq	1562	13	(	(	-LRB-
cord-010027-r0tl01kq	1562	14	2	2	CD
cord-010027-r0tl01kq	1562	15	months	month	NNS
cord-010027-r0tl01kq	1562	16	)	)	-RRB-
cord-010027-r0tl01kq	1562	17	requiring	require	VBG
cord-010027-r0tl01kq	1562	18	surgical	surgical	JJ
cord-010027-r0tl01kq	1562	19	resection	resection	NN
cord-010027-r0tl01kq	1562	20	under	under	IN
cord-010027-r0tl01kq	1562	21	general	general	JJ
cord-010027-r0tl01kq	1562	22	anaesthesia	anaesthesia	NN
cord-010027-r0tl01kq	1562	23	.	.	.
cord-010027-r0tl01kq	1563	1	Histological	histological	JJ
cord-010027-r0tl01kq	1563	2	examinations	examination	NNS
cord-010027-r0tl01kq	1563	3	revealed	reveal	VBD
cord-010027-r0tl01kq	1563	4	polypoid	polypoid	JJ
cord-010027-r0tl01kq	1563	5	lesions	lesion	NNS
cord-010027-r0tl01kq	1563	6	with	with	IN
cord-010027-r0tl01kq	1563	7	prominent	prominent	JJ
cord-010027-r0tl01kq	1563	8	pseudoepitheliomatous	pseudoepitheliomatous	JJ
cord-010027-r0tl01kq	1563	9	hyperplasia	hyperplasia	NN
cord-010027-r0tl01kq	1563	10	and	and	CC
cord-010027-r0tl01kq	1563	11	dense	dense	JJ
cord-010027-r0tl01kq	1563	12	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	1563	13	infiltrate	infiltrate	NN
cord-010027-r0tl01kq	1563	14	,	,	,
cord-010027-r0tl01kq	1563	15	composed	compose	VBN
cord-010027-r0tl01kq	1563	16	mainly	mainly	RB
cord-010027-r0tl01kq	1563	17	of	of	IN
cord-010027-r0tl01kq	1563	18	lymphocytes	lymphocyte	NNS
cord-010027-r0tl01kq	1563	19	and	and	CC
cord-010027-r0tl01kq	1563	20	plasma	plasma	NN
cord-010027-r0tl01kq	1563	21	cells	cell	NNS
cord-010027-r0tl01kq	1563	22	,	,	,
cord-010027-r0tl01kq	1563	23	extending	extend	VBG
cord-010027-r0tl01kq	1563	24	to	to	IN
cord-010027-r0tl01kq	1563	25	the	the	DT
cord-010027-r0tl01kq	1563	26	hypodermis	hypodermis	NNP
cord-010027-r0tl01kq	1563	27	.	.	.
cord-010027-r0tl01kq	1564	1	Numerous	numerous	JJ
cord-010027-r0tl01kq	1564	2	abscesses	abscess	NNS
cord-010027-r0tl01kq	1564	3	with	with	IN
cord-010027-r0tl01kq	1564	4	large	large	JJ
cord-010027-r0tl01kq	1564	5	numbers	number	NNS
cord-010027-r0tl01kq	1564	6	of	of	IN
cord-010027-r0tl01kq	1564	7	eosinophils	eosinophil	NNS
cord-010027-r0tl01kq	1564	8	were	be	VBD
cord-010027-r0tl01kq	1564	9	present	present	JJ
cord-010027-r0tl01kq	1564	10	withinin	withinin	NNP
cord-010027-r0tl01kq	1564	11	the	the	DT
cord-010027-r0tl01kq	1564	12	hyperplastic	hyperplastic	JJ
cord-010027-r0tl01kq	1564	13	epithelium	epithelium	NN
cord-010027-r0tl01kq	1564	14	.	.	.
cord-010027-r0tl01kq	1565	1	The	the	DT
cord-010027-r0tl01kq	1565	2	typical	typical	JJ
cord-010027-r0tl01kq	1565	3	intranuclear	intranuclear	NN
cord-010027-r0tl01kq	1565	4	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1565	5	of	of	IN
cord-010027-r0tl01kq	1565	6	herpes	herpes	NN
cord-010027-r0tl01kq	1565	7	simplex	simplex	NNP
cord-010027-r0tl01kq	1565	8	virus	virus	NN
cord-010027-r0tl01kq	1565	9	(	(	-LRB-
cord-010027-r0tl01kq	1565	10	HSV	HSV	NNP
cord-010027-r0tl01kq	1565	11	)	)	-RRB-
cord-010027-r0tl01kq	1565	12	were	be	VBD
cord-010027-r0tl01kq	1565	13	identified	identify	VBN
cord-010027-r0tl01kq	1565	14	.	.	.
cord-010027-r0tl01kq	1566	1	HSV	HSV	NNP
cord-010027-r0tl01kq	1566	2	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1566	3	was	be	VBD
cord-010027-r0tl01kq	1566	4	positive	positive	JJ
cord-010027-r0tl01kq	1566	5	.	.	.
cord-010027-r0tl01kq	1567	1	This	this	DT
cord-010027-r0tl01kq	1567	2	is	be	VBZ
cord-010027-r0tl01kq	1567	3	a	a	DT
cord-010027-r0tl01kq	1567	4	rare	rare	JJ
cord-010027-r0tl01kq	1567	5	case	case	NN
cord-010027-r0tl01kq	1567	6	of	of	IN
cord-010027-r0tl01kq	1567	7	vulval	vulval	JJ
cord-010027-r0tl01kq	1567	8	HSV	HSV	NNP
cord-010027-r0tl01kq	1567	9	warts	wart	NNS
cord-010027-r0tl01kq	1567	10	mimicking	mimic	VBG
cord-010027-r0tl01kq	1567	11	cancer	cancer	NN
cord-010027-r0tl01kq	1567	12	.	.	.
cord-010027-r0tl01kq	1568	1	Oral	oral	JJ
cord-010027-r0tl01kq	1568	2	acyclovir	acyclovir	NNP
cord-010027-r0tl01kq	1568	3	was	be	VBD
cord-010027-r0tl01kq	1568	4	administered	administer	VBN
cord-010027-r0tl01kq	1568	5	following	follow	VBG
cord-010027-r0tl01kq	1568	6	surgery	surgery	NN
cord-010027-r0tl01kq	1568	7	and	and	CC
cord-010027-r0tl01kq	1568	8	resulted	result	VBD
cord-010027-r0tl01kq	1568	9	in	in	IN
cord-010027-r0tl01kq	1568	10	good	good	JJ
cord-010027-r0tl01kq	1568	11	control	control	NN
cord-010027-r0tl01kq	1568	12	.	.	.
cord-010027-r0tl01kq	1569	1	Literature	literature	NN
cord-010027-r0tl01kq	1569	2	review	review	NN
cord-010027-r0tl01kq	1569	3	shows	show	VBZ
cord-010027-r0tl01kq	1569	4	only	only	RB
cord-010027-r0tl01kq	1569	5	6	6	CD
cord-010027-r0tl01kq	1569	6	previously	previously	RB
cord-010027-r0tl01kq	1569	7	described	describe	VBN
cord-010027-r0tl01kq	1569	8	cases	case	NNS
cord-010027-r0tl01kq	1569	9	of	of	IN
cord-010027-r0tl01kq	1569	10	verrucous	verrucous	JJ
cord-010027-r0tl01kq	1569	11	HSV	HSV	NNP
cord-010027-r0tl01kq	1569	12	,	,	,
cord-010027-r0tl01kq	1569	13	Types	Types	NNP
cord-010027-r0tl01kq	1569	14	1	1	CD
cord-010027-r0tl01kq	1569	15	and	and	CC
cord-010027-r0tl01kq	1569	16	2	2	CD
cord-010027-r0tl01kq	1569	17	,	,	,
cord-010027-r0tl01kq	1569	18	simulating	simulate	VBG
cord-010027-r0tl01kq	1569	19	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	1569	20	in	in	IN
cord-010027-r0tl01kq	1569	21	patients	patient	NNS
cord-010027-r0tl01kq	1569	22	with	with	IN
cord-010027-r0tl01kq	1569	23	AIDS	AIDS	NNP
cord-010027-r0tl01kq	1569	24	on	on	IN
cord-010027-r0tl01kq	1569	25	antiretroviral	antiretroviral	JJ
cord-010027-r0tl01kq	1569	26	therapy	therapy	NN
cord-010027-r0tl01kq	1569	27	.	.	.
cord-010027-r0tl01kq	1570	1	Primary	primary	JJ
cord-010027-r0tl01kq	1570	2	mucinous	mucinous	JJ
cord-010027-r0tl01kq	1570	3	eccrine	eccrine	JJ
cord-010027-r0tl01kq	1570	4	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1570	5	of	of	IN
cord-010027-r0tl01kq	1570	6	the	the	DT
cord-010027-r0tl01kq	1570	7	skin	skin	NN
cord-010027-r0tl01kq	1570	8	is	be	VBZ
cord-010027-r0tl01kq	1570	9	a	a	DT
cord-010027-r0tl01kq	1570	10	rare	rare	JJ
cord-010027-r0tl01kq	1570	11	adnexal	adnexal	NN
cord-010027-r0tl01kq	1570	12	neoplasm	neoplasm	NN
cord-010027-r0tl01kq	1570	13	,	,	,
cord-010027-r0tl01kq	1570	14	typically	typically	RB
cord-010027-r0tl01kq	1570	15	involving	involve	VBG
cord-010027-r0tl01kq	1570	16	the	the	DT
cord-010027-r0tl01kq	1570	17	head	head	NN
cord-010027-r0tl01kq	1570	18	and	and	CC
cord-010027-r0tl01kq	1570	19	neck	neck	NN
cord-010027-r0tl01kq	1570	20	region	region	NN
cord-010027-r0tl01kq	1570	21	in	in	IN
cord-010027-r0tl01kq	1570	22	the	the	DT
cord-010027-r0tl01kq	1570	23	elderly	elderly	JJ
cord-010027-r0tl01kq	1570	24	population	population	NN
cord-010027-r0tl01kq	1570	25	.	.	.
cord-010027-r0tl01kq	1571	1	Here	here	RB
cord-010027-r0tl01kq	1571	2	we	-PRON-	PRP
cord-010027-r0tl01kq	1571	3	present	present	VBP
cord-010027-r0tl01kq	1571	4	a	a	DT
cord-010027-r0tl01kq	1571	5	case	case	NN
cord-010027-r0tl01kq	1571	6	of	of	IN
cord-010027-r0tl01kq	1571	7	primary	primary	JJ
cord-010027-r0tl01kq	1571	8	mucinous	mucinous	JJ
cord-010027-r0tl01kq	1571	9	eccrine	eccrine	JJ
cord-010027-r0tl01kq	1571	10	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1571	11	of	of	IN
cord-010027-r0tl01kq	1571	12	the	the	DT
cord-010027-r0tl01kq	1571	13	vulva	vulva	NN
cord-010027-r0tl01kq	1571	14	;	;	:
cord-010027-r0tl01kq	1571	15	occurrence	occurrence	NN
cord-010027-r0tl01kq	1571	16	at	at	IN
cord-010027-r0tl01kq	1571	17	this	this	DT
cord-010027-r0tl01kq	1571	18	site	site	NN
cord-010027-r0tl01kq	1571	19	is	be	VBZ
cord-010027-r0tl01kq	1571	20	extremely	extremely	RB
cord-010027-r0tl01kq	1571	21	rare	rare	JJ
cord-010027-r0tl01kq	1571	22	,	,	,
cord-010027-r0tl01kq	1571	23	with	with	IN
cord-010027-r0tl01kq	1571	24	only	only	RB
cord-010027-r0tl01kq	1571	25	five	five	CD
cord-010027-r0tl01kq	1571	26	cases	case	NNS
cord-010027-r0tl01kq	1571	27	published	publish	VBN
cord-010027-r0tl01kq	1571	28	in	in	IN
cord-010027-r0tl01kq	1571	29	English	english	JJ
cord-010027-r0tl01kq	1571	30	literature	literature	NN
cord-010027-r0tl01kq	1571	31	.	.	.
cord-010027-r0tl01kq	1572	1	A	a	DT
cord-010027-r0tl01kq	1572	2	62	62	CD
cord-010027-r0tl01kq	1572	3	year	year	NN
cord-010027-r0tl01kq	1572	4	old	old	JJ
cord-010027-r0tl01kq	1572	5	female	female	NN
cord-010027-r0tl01kq	1572	6	presented	present	VBN
cord-010027-r0tl01kq	1572	7	with	with	IN
cord-010027-r0tl01kq	1572	8	a	a	DT
cord-010027-r0tl01kq	1572	9	10	10	CD
cord-010027-r0tl01kq	1572	10	mm	mm	NN
cord-010027-r0tl01kq	1572	11	vulval	vulval	JJ
cord-010027-r0tl01kq	1572	12	lesion	lesion	NN
cord-010027-r0tl01kq	1572	13	,	,	,
cord-010027-r0tl01kq	1572	14	clinically	clinically	RB
cord-010027-r0tl01kq	1572	15	suspected	suspect	VBN
cord-010027-r0tl01kq	1572	16	to	to	TO
cord-010027-r0tl01kq	1572	17	be	be	VB
cord-010027-r0tl01kq	1572	18	an	an	DT
cord-010027-r0tl01kq	1572	19	inclusion	inclusion	NN
cord-010027-r0tl01kq	1572	20	cyst	cyst	NN
cord-010027-r0tl01kq	1572	21	.	.	.
cord-010027-r0tl01kq	1573	1	The	the	DT
cord-010027-r0tl01kq	1573	2	lesion	lesion	NN
cord-010027-r0tl01kq	1573	3	was	be	VBD
cord-010027-r0tl01kq	1573	4	removed	remove	VBN
cord-010027-r0tl01kq	1573	5	and	and	CC
cord-010027-r0tl01kq	1573	6	sent	send	VBN
cord-010027-r0tl01kq	1573	7	for	for	IN
cord-010027-r0tl01kq	1573	8	histopathological	histopathological	NNP
cord-010027-r0tl01kq	1573	9	assessment	assessment	NN
cord-010027-r0tl01kq	1573	10	.	.	.
cord-010027-r0tl01kq	1574	1	Histological	histological	JJ
cord-010027-r0tl01kq	1574	2	examination	examination	NN
cord-010027-r0tl01kq	1574	3	revealed	reveal	VBD
cord-010027-r0tl01kq	1574	4	a	a	DT
cord-010027-r0tl01kq	1574	5	well	well	RB
cord-010027-r0tl01kq	1574	6	circumscribed	circumscribed	JJ
cord-010027-r0tl01kq	1574	7	,	,	,
cord-010027-r0tl01kq	1574	8	partly	partly	RB
cord-010027-r0tl01kq	1574	9	encapsulated	encapsulate	VBN
cord-010027-r0tl01kq	1574	10	tumour	tumour	NN
cord-010027-r0tl01kq	1574	11	composed	compose	VBN
cord-010027-r0tl01kq	1574	12	of	of	IN
cord-010027-r0tl01kq	1574	13	rounded	rounded	JJ
cord-010027-r0tl01kq	1574	14	and	and	CC
cord-010027-r0tl01kq	1574	15	irregular	irregular	JJ
cord-010027-r0tl01kq	1574	16	nests	nest	NNS
cord-010027-r0tl01kq	1574	17	of	of	IN
cord-010027-r0tl01kq	1574	18	polygonal	polygonal	JJ
cord-010027-r0tl01kq	1574	19	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1574	20	cells	cell	NNS
cord-010027-r0tl01kq	1574	21	with	with	IN
cord-010027-r0tl01kq	1574	22	scattered	scatter	VBN
cord-010027-r0tl01kq	1574	23	lumina	lumina	NNP
cord-010027-r0tl01kq	1574	24	,	,	,
cord-010027-r0tl01kq	1574	25	suspended	suspend	VBN
cord-010027-r0tl01kq	1574	26	in	in	IN
cord-010027-r0tl01kq	1574	27	pools	pool	NNS
cord-010027-r0tl01kq	1574	28	of	of	IN
cord-010027-r0tl01kq	1574	29	extracellular	extracellular	JJ
cord-010027-r0tl01kq	1574	30	mucin	mucin	NN
cord-010027-r0tl01kq	1574	31	.	.	.
cord-010027-r0tl01kq	1575	1	The	the	DT
cord-010027-r0tl01kq	1575	2	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1575	3	cell	cell	NN
cord-010027-r0tl01kq	1575	4	nuclei	nucleus	NNS
cord-010027-r0tl01kq	1575	5	displayed	display	VBD
cord-010027-r0tl01kq	1575	6	a	a	DT
cord-010027-r0tl01kq	1575	7	uniform	uniform	JJ
cord-010027-r0tl01kq	1575	8	chromatin	chromatin	NN
cord-010027-r0tl01kq	1575	9	pattern	pattern	NN
cord-010027-r0tl01kq	1575	10	with	with	IN
cord-010027-r0tl01kq	1575	11	small	small	JJ
cord-010027-r0tl01kq	1575	12	distinct	distinct	JJ
cord-010027-r0tl01kq	1575	13	nucleoli	nucleolus	NNS
cord-010027-r0tl01kq	1575	14	.	.	.
cord-010027-r0tl01kq	1576	1	The	the	DT
cord-010027-r0tl01kq	1576	2	mucin	mucin	NN
cord-010027-r0tl01kq	1576	3	pools	pool	NNS
cord-010027-r0tl01kq	1576	4	stained	stain	VBN
cord-010027-r0tl01kq	1576	5	positive	positive	JJ
cord-010027-r0tl01kq	1576	6	for	for	IN
cord-010027-r0tl01kq	1576	7	Alcian	alcian	JJ
cord-010027-r0tl01kq	1576	8	blue	blue	NN
cord-010027-r0tl01kq	1576	9	and	and	CC
cord-010027-r0tl01kq	1576	10	dPAS	dpas	NN
cord-010027-r0tl01kq	1576	11	.	.	.
cord-010027-r0tl01kq	1577	1	Immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	1577	2	staining	stain	VBG
cord-010027-r0tl01kq	1577	3	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	1577	4	positivity	positivity	NN
cord-010027-r0tl01kq	1577	5	for	for	IN
cord-010027-r0tl01kq	1577	6	CEA	CEA	NNP
cord-010027-r0tl01kq	1577	7	,	,	,
cord-010027-r0tl01kq	1577	8	CK7	CK7	NNP
cord-010027-r0tl01kq	1577	9	,	,	,
cord-010027-r0tl01kq	1577	10	GCDFP	GCDFP	NNP
cord-010027-r0tl01kq	1577	11	,	,	,
cord-010027-r0tl01kq	1577	12	oestrogen	oestrogen	NN
cord-010027-r0tl01kq	1577	13	receptor	receptor	NN
cord-010027-r0tl01kq	1577	14	,	,	,
cord-010027-r0tl01kq	1577	15	progesterone	progesterone	NN
cord-010027-r0tl01kq	1577	16	receptor	receptor	NN
cord-010027-r0tl01kq	1577	17	,	,	,
cord-010027-r0tl01kq	1577	18	synaptophysin	synaptophysin	NNP
cord-010027-r0tl01kq	1577	19	and	and	CC
cord-010027-r0tl01kq	1577	20	chromogranin	chromogranin	NNP
cord-010027-r0tl01kq	1577	21	.	.	.
cord-010027-r0tl01kq	1578	1	Immunostaining	immunostaine	VBG
cord-010027-r0tl01kq	1578	2	was	be	VBD
cord-010027-r0tl01kq	1578	3	negative	negative	JJ
cord-010027-r0tl01kq	1578	4	for	for	IN
cord-010027-r0tl01kq	1578	5	CK20	CK20	NNP
cord-010027-r0tl01kq	1578	6	,	,	,
cord-010027-r0tl01kq	1578	7	CDX2	CDX2	NNP
cord-010027-r0tl01kq	1578	8	,	,	,
cord-010027-r0tl01kq	1578	9	CA-125	ca-125	NN
cord-010027-r0tl01kq	1578	10	,	,	,
cord-010027-r0tl01kq	1578	11	TTF-1	TTF-1	NNP
cord-010027-r0tl01kq	1578	12	,	,	,
cord-010027-r0tl01kq	1578	13	CH5/6	CH5/6	NNP
cord-010027-r0tl01kq	1578	14	,	,	,
cord-010027-r0tl01kq	1578	15	CK14	CK14	NNP
cord-010027-r0tl01kq	1578	16	,	,	,
cord-010027-r0tl01kq	1578	17	HER-2	HER-2	NNP
cord-010027-r0tl01kq	1578	18	,	,	,
cord-010027-r0tl01kq	1578	19	WT-1	WT-1	NNP
cord-010027-r0tl01kq	1578	20	,	,	,
cord-010027-r0tl01kq	1578	21	CD56	CD56	NNP
cord-010027-r0tl01kq	1578	22	and	and	CC
cord-010027-r0tl01kq	1578	23	S100	S100	NNP
cord-010027-r0tl01kq	1578	24	.	.	.
cord-010027-r0tl01kq	1579	1	Ki-67	Ki-67	.
cord-010027-r0tl01kq	1580	1	proliferation	proliferation	NN
cord-010027-r0tl01kq	1580	2	fraction	fraction	NN
cord-010027-r0tl01kq	1580	3	was	be	VBD
cord-010027-r0tl01kq	1580	4	approximately	approximately	RB
cord-010027-r0tl01kq	1580	5	5	5	CD
cord-010027-r0tl01kq	1580	6	%	%	NN
cord-010027-r0tl01kq	1580	7	.	.	.
cord-010027-r0tl01kq	1581	1	Overall	overall	RB
cord-010027-r0tl01kq	1581	2	,	,	,
cord-010027-r0tl01kq	1581	3	the	the	DT
cord-010027-r0tl01kq	1581	4	findings	finding	NNS
cord-010027-r0tl01kq	1581	5	were	be	VBD
cord-010027-r0tl01kq	1581	6	those	those	DT
cord-010027-r0tl01kq	1581	7	of	of	IN
cord-010027-r0tl01kq	1581	8	a	a	DT
cord-010027-r0tl01kq	1581	9	mucinous	mucinous	JJ
cord-010027-r0tl01kq	1581	10	eccrine	eccrine	JJ
cord-010027-r0tl01kq	1581	11	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1581	12	with	with	IN
cord-010027-r0tl01kq	1581	13	neuroendocrine	neuroendocrine	JJ
cord-010027-r0tl01kq	1581	14	differentiation	differentiation	NN
cord-010027-r0tl01kq	1581	15	.	.	.
cord-010027-r0tl01kq	1582	1	Following	follow	VBG
cord-010027-r0tl01kq	1582	2	multidisciplinary	multidisciplinary	JJ
cord-010027-r0tl01kq	1582	3	discussion	discussion	NN
cord-010027-r0tl01kq	1582	4	,	,	,
cord-010027-r0tl01kq	1582	5	and	and	CC
cord-010027-r0tl01kq	1582	6	negative	negative	JJ
cord-010027-r0tl01kq	1582	7	imaging	imaging	NN
cord-010027-r0tl01kq	1582	8	of	of	IN
cord-010027-r0tl01kq	1582	9	the	the	DT
cord-010027-r0tl01kq	1582	10	breasts	breast	NNS
cord-010027-r0tl01kq	1582	11	and	and	CC
cord-010027-r0tl01kq	1582	12	gastrointestinal	gastrointestinal	JJ
cord-010027-r0tl01kq	1582	13	tract	tract	NN
cord-010027-r0tl01kq	1582	14	,	,	,
cord-010027-r0tl01kq	1582	15	a	a	DT
cord-010027-r0tl01kq	1582	16	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1582	17	of	of	IN
cord-010027-r0tl01kq	1582	18	primary	primary	JJ
cord-010027-r0tl01kq	1582	19	mucinous	mucinous	JJ
cord-010027-r0tl01kq	1582	20	eccrine	eccrine	JJ
cord-010027-r0tl01kq	1582	21	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1582	22	of	of	IN
cord-010027-r0tl01kq	1582	23	the	the	DT
cord-010027-r0tl01kq	1582	24	vulva	vulva	NN
cord-010027-r0tl01kq	1582	25	was	be	VBD
cord-010027-r0tl01kq	1582	26	reached	reach	VBN
cord-010027-r0tl01kq	1582	27	.	.	.
cord-010027-r0tl01kq	1583	1	Only	only	RB
cord-010027-r0tl01kq	1583	2	a	a	DT
cord-010027-r0tl01kq	1583	3	handful	handful	NN
cord-010027-r0tl01kq	1583	4	of	of	IN
cord-010027-r0tl01kq	1583	5	cases	case	NNS
cord-010027-r0tl01kq	1583	6	of	of	IN
cord-010027-r0tl01kq	1583	7	primary	primary	JJ
cord-010027-r0tl01kq	1583	8	mucinous	mucinous	JJ
cord-010027-r0tl01kq	1583	9	eccrine	eccrine	JJ
cord-010027-r0tl01kq	1583	10	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1583	11	of	of	IN
cord-010027-r0tl01kq	1583	12	the	the	DT
cord-010027-r0tl01kq	1583	13	vulva	vulva	NN
cord-010027-r0tl01kq	1583	14	have	have	VBP
cord-010027-r0tl01kq	1583	15	been	be	VBN
cord-010027-r0tl01kq	1583	16	reported	report	VBN
cord-010027-r0tl01kq	1583	17	.	.	.
cord-010027-r0tl01kq	1584	1	Metastatic	metastatic	JJ
cord-010027-r0tl01kq	1584	2	disease	disease	NN
cord-010027-r0tl01kq	1584	3	,	,	,
cord-010027-r0tl01kq	1584	4	particularly	particularly	RB
cord-010027-r0tl01kq	1584	5	from	from	IN
cord-010027-r0tl01kq	1584	6	breast	breast	NN
cord-010027-r0tl01kq	1584	7	and	and	CC
cord-010027-r0tl01kq	1584	8	colon	colon	NN
cord-010027-r0tl01kq	1584	9	,	,	,
cord-010027-r0tl01kq	1584	10	must	must	MD
cord-010027-r0tl01kq	1584	11	be	be	VB
cord-010027-r0tl01kq	1584	12	excluded	exclude	VBN
cord-010027-r0tl01kq	1584	13	.	.	.
cord-010027-r0tl01kq	1585	1	Follow	follow	VB
cord-010027-r0tl01kq	1585	2	up	up	RP
cord-010027-r0tl01kq	1585	3	data	datum	NNS
cord-010027-r0tl01kq	1585	4	from	from	IN
cord-010027-r0tl01kq	1585	5	patients	patient	NNS
cord-010027-r0tl01kq	1585	6	with	with	IN
cord-010027-r0tl01kq	1585	7	primary	primary	JJ
cord-010027-r0tl01kq	1585	8	mucinous	mucinous	JJ
cord-010027-r0tl01kq	1585	9	eccrine	eccrine	JJ
cord-010027-r0tl01kq	1585	10	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1585	11	of	of	IN
cord-010027-r0tl01kq	1585	12	the	the	DT
cord-010027-r0tl01kq	1585	13	skin	skin	NN
cord-010027-r0tl01kq	1585	14	suggests	suggest	VBZ
cord-010027-r0tl01kq	1585	15	a	a	DT
cord-010027-r0tl01kq	1585	16	high	high	JJ
cord-010027-r0tl01kq	1585	17	local	local	JJ
cord-010027-r0tl01kq	1585	18	recurrence	recurrence	NN
cord-010027-r0tl01kq	1585	19	rate	rate	NN
cord-010027-r0tl01kq	1585	20	(	(	-LRB-
cord-010027-r0tl01kq	1585	21	29.4	29.4	CD
cord-010027-r0tl01kq	1585	22	%	%	NN
cord-010027-r0tl01kq	1585	23	)	)	-RRB-
cord-010027-r0tl01kq	1585	24	,	,	,
cord-010027-r0tl01kq	1585	25	necessitating	necessitate	VBG
cord-010027-r0tl01kq	1585	26	close	close	JJ
cord-010027-r0tl01kq	1585	27	follow	follow	NN
cord-010027-r0tl01kq	1585	28	-	-	HYPH
cord-010027-r0tl01kq	1585	29	up	up	NN
cord-010027-r0tl01kq	1585	30	.	.	.
cord-010027-r0tl01kq	1586	1	However	however	RB
cord-010027-r0tl01kq	1586	2	,	,	,
cord-010027-r0tl01kq	1586	3	risk	risk	NN
cord-010027-r0tl01kq	1586	4	of	of	IN
cord-010027-r0tl01kq	1586	5	metastasis	metastasis	NN
cord-010027-r0tl01kq	1586	6	is	be	VBZ
cord-010027-r0tl01kq	1586	7	low	low	JJ
cord-010027-r0tl01kq	1586	8	(	(	-LRB-
cord-010027-r0tl01kq	1586	9	9.6	9.6	CD
cord-010027-r0tl01kq	1586	10	%	%	NN
cord-010027-r0tl01kq	1586	11	)	)	-RRB-
cord-010027-r0tl01kq	1586	12	.	.	.
cord-010027-r0tl01kq	1587	1	Royal	Royal	NNP
cord-010027-r0tl01kq	1587	2	Shrewsbury	Shrewsbury	NNP
cord-010027-r0tl01kq	1587	3	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1587	4	,	,	,
cord-010027-r0tl01kq	1587	5	Shrewsbury	Shrewsbury	NNP
cord-010027-r0tl01kq	1587	6	,	,	,
cord-010027-r0tl01kq	1587	7	UK	UK	NNP
cord-010027-r0tl01kq	1587	8	Introduction	introduction	NN
cord-010027-r0tl01kq	1587	9	:	:	:
cord-010027-r0tl01kq	1587	10	Primary	Primary	NNP
cord-010027-r0tl01kq	1587	11	Extraskeletal	Extraskeletal	NNP
cord-010027-r0tl01kq	1587	12	Myxoid	Myxoid	NNP
cord-010027-r0tl01kq	1587	13	Chondrosaroma	Chondrosaroma	NNP
cord-010027-r0tl01kq	1587	14	(	(	-LRB-
cord-010027-r0tl01kq	1587	15	EMC	EMC	NNP
cord-010027-r0tl01kq	1587	16	)	)	-RRB-
cord-010027-r0tl01kq	1587	17	of	of	IN
cord-010027-r0tl01kq	1587	18	the	the	DT
cord-010027-r0tl01kq	1587	19	vulva	vulva	NN
cord-010027-r0tl01kq	1587	20	is	be	VBZ
cord-010027-r0tl01kq	1587	21	a	a	DT
cord-010027-r0tl01kq	1587	22	rare	rare	JJ
cord-010027-r0tl01kq	1587	23	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	1587	24	neoplasm	neoplasm	NN
cord-010027-r0tl01kq	1587	25	.	.	.
cord-010027-r0tl01kq	1588	1	The	the	DT
cord-010027-r0tl01kq	1588	2	myxoid	myxoid	NN
cord-010027-r0tl01kq	1588	3	tumour	tumour	NN
cord-010027-r0tl01kq	1588	4	differential	differential	JJ
cord-010027-r0tl01kq	1588	5	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1588	6	on	on	IN
cord-010027-r0tl01kq	1588	7	a	a	DT
cord-010027-r0tl01kq	1588	8	core	core	NN
cord-010027-r0tl01kq	1588	9	biopsy	biopsy	NN
cord-010027-r0tl01kq	1588	10	can	can	MD
cord-010027-r0tl01kq	1588	11	be	be	VB
cord-010027-r0tl01kq	1588	12	quite	quite	RB
cord-010027-r0tl01kq	1588	13	challinging	challinge	VBG
cord-010027-r0tl01kq	1588	14	.	.	.
cord-010027-r0tl01kq	1589	1	To	to	IN
cord-010027-r0tl01kq	1589	2	date	date	NN
cord-010027-r0tl01kq	1589	3	,	,	,
cord-010027-r0tl01kq	1589	4	few	few	JJ
cord-010027-r0tl01kq	1589	5	cases	case	NNS
cord-010027-r0tl01kq	1589	6	have	have	VBP
cord-010027-r0tl01kq	1589	7	been	be	VBN
cord-010027-r0tl01kq	1589	8	reported	report	VBN
cord-010027-r0tl01kq	1589	9	in	in	IN
cord-010027-r0tl01kq	1589	10	the	the	DT
cord-010027-r0tl01kq	1589	11	literature	literature	NN
cord-010027-r0tl01kq	1589	12	.	.	.
cord-010027-r0tl01kq	1590	1	Case	Case	NNP
cord-010027-r0tl01kq	1590	2	Report	Report	NNP
cord-010027-r0tl01kq	1590	3	:	:	:
cord-010027-r0tl01kq	1590	4	A	a	DT
cord-010027-r0tl01kq	1590	5	42-year	42-year	JJ
cord-010027-r0tl01kq	1590	6	old	old	JJ
cord-010027-r0tl01kq	1590	7	woman	woman	NN
cord-010027-r0tl01kq	1590	8	noticed	notice	VBD
cord-010027-r0tl01kq	1590	9	a	a	DT
cord-010027-r0tl01kq	1590	10	swelling	swelling	NN
cord-010027-r0tl01kq	1590	11	on	on	IN
cord-010027-r0tl01kq	1590	12	the	the	DT
cord-010027-r0tl01kq	1590	13	right	right	JJ
cord-010027-r0tl01kq	1590	14	side	side	NN
cord-010027-r0tl01kq	1590	15	of	of	IN
cord-010027-r0tl01kq	1590	16	the	the	DT
cord-010027-r0tl01kq	1590	17	labia	labium	NNS
cord-010027-r0tl01kq	1590	18	,	,	,
cord-010027-r0tl01kq	1590	19	thought	think	VBD
cord-010027-r0tl01kq	1590	20	to	to	TO
cord-010027-r0tl01kq	1590	21	be	be	VB
cord-010027-r0tl01kq	1590	22	a	a	DT
cord-010027-r0tl01kq	1590	23	Bartholin	Bartholin	NNP
cord-010027-r0tl01kq	1590	24	's	's	POS
cord-010027-r0tl01kq	1590	25	cyst	cyst	NN
cord-010027-r0tl01kq	1590	26	in	in	IN
cord-010027-r0tl01kq	1590	27	2011	2011	CD
cord-010027-r0tl01kq	1590	28	.	.	.
cord-010027-r0tl01kq	1591	1	She	-PRON-	PRP
cord-010027-r0tl01kq	1591	2	was	be	VBD
cord-010027-r0tl01kq	1591	3	managed	manage	VBN
cord-010027-r0tl01kq	1591	4	conservatively	conservatively	RB
cord-010027-r0tl01kq	1591	5	.	.	.
cord-010027-r0tl01kq	1592	1	She	-PRON-	PRP
cord-010027-r0tl01kq	1592	2	had	have	VBD
cord-010027-r0tl01kq	1592	3	drainage	drainage	NN
cord-010027-r0tl01kq	1592	4	and	and	CC
cord-010027-r0tl01kq	1592	5	marsupialization	marsupialization	NN
cord-010027-r0tl01kq	1592	6	under	under	IN
cord-010027-r0tl01kq	1592	7	general	general	JJ
cord-010027-r0tl01kq	1592	8	anaesthesia	anaesthesia	NN
cord-010027-r0tl01kq	1592	9	.	.	.
cord-010027-r0tl01kq	1593	1	This	this	DT
cord-010027-r0tl01kq	1593	2	resulted	result	VBD
cord-010027-r0tl01kq	1593	3	in	in	IN
cord-010027-r0tl01kq	1593	4	extreme	extreme	JJ
cord-010027-r0tl01kq	1593	5	bruising	bruising	NN
cord-010027-r0tl01kq	1593	6	of	of	IN
cord-010027-r0tl01kq	1593	7	the	the	DT
cord-010027-r0tl01kq	1593	8	vulva	vulva	NN
cord-010027-r0tl01kq	1593	9	.	.	.
cord-010027-r0tl01kq	1594	1	This	this	DT
cord-010027-r0tl01kq	1594	2	was	be	VBD
cord-010027-r0tl01kq	1594	3	managed	manage	VBN
cord-010027-r0tl01kq	1594	4	with	with	IN
cord-010027-r0tl01kq	1594	5	antibiotics	antibiotic	NNS
cord-010027-r0tl01kq	1594	6	and	and	CC
cord-010027-r0tl01kq	1594	7	non	non	JJ
cord-010027-r0tl01kq	1594	8	-	-	JJ
cord-010027-r0tl01kq	1594	9	steroidal	steroidal	JJ
cord-010027-r0tl01kq	1594	10	anti	anti	JJ
cord-010027-r0tl01kq	1594	11	-	-	JJ
cord-010027-r0tl01kq	1594	12	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	1594	13	medication	medication	NN
cord-010027-r0tl01kq	1594	14	,	,	,
cord-010027-r0tl01kq	1594	15	and	and	CC
cord-010027-r0tl01kq	1594	16	it	-PRON-	PRP
cord-010027-r0tl01kq	1594	17	resolved	resolve	VBD
cord-010027-r0tl01kq	1594	18	after	after	IN
cord-010027-r0tl01kq	1594	19	3	3	CD
cord-010027-r0tl01kq	1594	20	weeks	week	NNS
cord-010027-r0tl01kq	1594	21	.	.	.
cord-010027-r0tl01kq	1595	1	Six	six	CD
cord-010027-r0tl01kq	1595	2	months	month	NNS
cord-010027-r0tl01kq	1595	3	later	later	RB
cord-010027-r0tl01kq	1595	4	,	,	,
cord-010027-r0tl01kq	1595	5	the	the	DT
cord-010027-r0tl01kq	1595	6	patient	patient	NN
cord-010027-r0tl01kq	1595	7	presented	present	VBN
cord-010027-r0tl01kq	1595	8	again	again	RB
cord-010027-r0tl01kq	1595	9	with	with	IN
cord-010027-r0tl01kq	1595	10	a	a	DT
cord-010027-r0tl01kq	1595	11	persistent	persistent	JJ
cord-010027-r0tl01kq	1595	12	vulval	vulval	JJ
cord-010027-r0tl01kq	1595	13	mass	mass	NN
cord-010027-r0tl01kq	1595	14	.	.	.
cord-010027-r0tl01kq	1596	1	A	a	DT
cord-010027-r0tl01kq	1596	2	biopsy	biopsy	NN
cord-010027-r0tl01kq	1596	3	was	be	VBD
cord-010027-r0tl01kq	1596	4	obtained	obtain	VBN
cord-010027-r0tl01kq	1596	5	under	under	IN
cord-010027-r0tl01kq	1596	6	general	general	JJ
cord-010027-r0tl01kq	1596	7	anaesthesia	anaesthesia	NN
cord-010027-r0tl01kq	1596	8	,	,	,
cord-010027-r0tl01kq	1596	9	and	and	CC
cord-010027-r0tl01kq	1596	10	it	-PRON-	PRP
cord-010027-r0tl01kq	1596	11	showed	show	VBD
cord-010027-r0tl01kq	1596	12	a	a	DT
cord-010027-r0tl01kq	1596	13	myxoid	myxoid	NN
cord-010027-r0tl01kq	1596	14	tumour	tumour	NN
cord-010027-r0tl01kq	1596	15	with	with	IN
cord-010027-r0tl01kq	1596	16	differential	differential	JJ
cord-010027-r0tl01kq	1596	17	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1596	18	of	of	IN
cord-010027-r0tl01kq	1596	19	low	low	JJ
cord-010027-r0tl01kq	1596	20	grade	grade	NN
cord-010027-r0tl01kq	1596	21	chondroid	chondroid	NN
cord-010027-r0tl01kq	1596	22	tumour	tumour	NN
cord-010027-r0tl01kq	1596	23	.	.	.
cord-010027-r0tl01kq	1597	1	An	an	DT
cord-010027-r0tl01kq	1597	2	MRI	MRI	NNP
cord-010027-r0tl01kq	1597	3	was	be	VBD
cord-010027-r0tl01kq	1597	4	performed	perform	VBN
cord-010027-r0tl01kq	1597	5	to	to	TO
cord-010027-r0tl01kq	1597	6	assess	assess	VB
cord-010027-r0tl01kq	1597	7	the	the	DT
cord-010027-r0tl01kq	1597	8	extent	extent	NN
cord-010027-r0tl01kq	1597	9	of	of	IN
cord-010027-r0tl01kq	1597	10	the	the	DT
cord-010027-r0tl01kq	1597	11	disease	disease	NN
cord-010027-r0tl01kq	1597	12	.	.	.
cord-010027-r0tl01kq	1598	1	The	the	DT
cord-010027-r0tl01kq	1598	2	tumour	tumour	NN
cord-010027-r0tl01kq	1598	3	was	be	VBD
cord-010027-r0tl01kq	1598	4	excised	excise	VBN
cord-010027-r0tl01kq	1598	5	.	.	.
cord-010027-r0tl01kq	1599	1	At	at	IN
cord-010027-r0tl01kq	1599	2	surgery	surgery	NN
cord-010027-r0tl01kq	1599	3	,	,	,
cord-010027-r0tl01kq	1599	4	a	a	DT
cord-010027-r0tl01kq	1599	5	7	7	CD
cord-010027-r0tl01kq	1599	6	x	x	SYM
cord-010027-r0tl01kq	1599	7	5	5	CD
cord-010027-r0tl01kq	1599	8	cm	cm	NNS
cord-010027-r0tl01kq	1599	9	lobulated	lobulate	VBN
cord-010027-r0tl01kq	1599	10	,	,	,
cord-010027-r0tl01kq	1599	11	extremely	extremely	RB
cord-010027-r0tl01kq	1599	12	vascular	vascular	JJ
cord-010027-r0tl01kq	1599	13	vulval	vulval	JJ
cord-010027-r0tl01kq	1599	14	tumour	tumour	NN
cord-010027-r0tl01kq	1599	15	was	be	VBD
cord-010027-r0tl01kq	1599	16	found	find	VBN
cord-010027-r0tl01kq	1599	17	.	.	.
cord-010027-r0tl01kq	1600	1	The	the	DT
cord-010027-r0tl01kq	1600	2	tumour	tumour	NN
cord-010027-r0tl01kq	1600	3	was	be	VBD
cord-010027-r0tl01kq	1600	4	inseparable	inseparable	JJ
cord-010027-r0tl01kq	1600	5	from	from	IN
cord-010027-r0tl01kq	1600	6	the	the	DT
cord-010027-r0tl01kq	1600	7	inferior	inferior	JJ
cord-010027-r0tl01kq	1600	8	pubic	pubic	NN
cord-010027-r0tl01kq	1600	9	ramus	ramus	NN
cord-010027-r0tl01kq	1600	10	of	of	IN
cord-010027-r0tl01kq	1600	11	the	the	DT
cord-010027-r0tl01kq	1600	12	pelvic	pelvic	JJ
cord-010027-r0tl01kq	1600	13	bone	bone	NN
cord-010027-r0tl01kq	1600	14	.	.	.
cord-010027-r0tl01kq	1601	1	A	a	DT
cord-010027-r0tl01kq	1601	2	complete	complete	JJ
cord-010027-r0tl01kq	1601	3	macroscopic	macroscopic	JJ
cord-010027-r0tl01kq	1601	4	resection	resection	NN
cord-010027-r0tl01kq	1601	5	was	be	VBD
cord-010027-r0tl01kq	1601	6	obtained	obtain	VBN
cord-010027-r0tl01kq	1601	7	.	.	.
cord-010027-r0tl01kq	1602	1	Histology	histology	NN
cord-010027-r0tl01kq	1602	2	confirmed	confirm	VBD
cord-010027-r0tl01kq	1602	3	low	low	JJ
cord-010027-r0tl01kq	1602	4	grade	grade	NN
cord-010027-r0tl01kq	1602	5	myxoid	myxoid	NN
cord-010027-r0tl01kq	1602	6	chondrosarcoma	chondrosarcoma	NNP
cord-010027-r0tl01kq	1602	7	.	.	.
cord-010027-r0tl01kq	1603	1	Conculsion	Conculsion	NNP
cord-010027-r0tl01kq	1603	2	:	:	:
cord-010027-r0tl01kq	1604	1	Vulval	Vulval	NNP
cord-010027-r0tl01kq	1604	2	lesions	lesion	NNS
cord-010027-r0tl01kq	1604	3	with	with	IN
cord-010027-r0tl01kq	1604	4	unusual	unusual	JJ
cord-010027-r0tl01kq	1604	5	characteristics	characteristic	NNS
cord-010027-r0tl01kq	1604	6	or	or	CC
cord-010027-r0tl01kq	1604	7	insidious	insidious	JJ
cord-010027-r0tl01kq	1604	8	evolution	evolution	NN
cord-010027-r0tl01kq	1604	9	in	in	IN
cord-010027-r0tl01kq	1604	10	the	the	DT
cord-010027-r0tl01kq	1604	11	labia	labium	NNS
cord-010027-r0tl01kq	1604	12	majora	majora	NNP
cord-010027-r0tl01kq	1604	13	or	or	CC
cord-010027-r0tl01kq	1604	14	Bartholin	Bartholin	NNP
cord-010027-r0tl01kq	1604	15	's	's	POS
cord-010027-r0tl01kq	1604	16	glands	gland	NNS
cord-010027-r0tl01kq	1604	17	area	area	NN
cord-010027-r0tl01kq	1604	18	should	should	MD
cord-010027-r0tl01kq	1604	19	be	be	VB
cord-010027-r0tl01kq	1604	20	carefully	carefully	RB
cord-010027-r0tl01kq	1604	21	and	and	CC
cord-010027-r0tl01kq	1604	22	promptly	promptly	RB
cord-010027-r0tl01kq	1604	23	investigated	investigate	VBD
cord-010027-r0tl01kq	1604	24	.	.	.
cord-010027-r0tl01kq	1605	1	Differential	differential	JJ
cord-010027-r0tl01kq	1605	2	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1605	3	of	of	IN
cord-010027-r0tl01kq	1605	4	myxoid	myxoid	NN
cord-010027-r0tl01kq	1605	5	tumours	tumour	NNS
cord-010027-r0tl01kq	1605	6	in	in	IN
cord-010027-r0tl01kq	1605	7	the	the	DT
cord-010027-r0tl01kq	1605	8	vulva	vulva	NN
cord-010027-r0tl01kq	1605	9	should	should	MD
cord-010027-r0tl01kq	1605	10	include	include	VB
cord-010027-r0tl01kq	1605	11	myxoid	myxoid	NNP
cord-010027-r0tl01kq	1605	12	chondrosarcoma	chondrosarcoma	NNP
cord-010027-r0tl01kq	1605	13	amongst	amongst	IN
cord-010027-r0tl01kq	1605	14	other	other	JJ
cord-010027-r0tl01kq	1605	15	diagnoses	diagnosis	NNS
cord-010027-r0tl01kq	1605	16	.	.	.
cord-010027-r0tl01kq	1606	1	(	(	-LRB-
cord-010027-r0tl01kq	1606	2	FISH	FISH	NNP
cord-010027-r0tl01kq	1606	3	)	)	-RRB-
cord-010027-r0tl01kq	1606	4	showed	show	VBD
cord-010027-r0tl01kq	1606	5	the	the	DT
cord-010027-r0tl01kq	1606	6	presence	presence	NN
cord-010027-r0tl01kq	1606	7	of	of	IN
cord-010027-r0tl01kq	1606	8	a	a	DT
cord-010027-r0tl01kq	1606	9	BCL2	BCL2	NNP
cord-010027-r0tl01kq	1606	10	rearrangement	rearrangement	NN
cord-010027-r0tl01kq	1606	11	in	in	IN
cord-010027-r0tl01kq	1606	12	a	a	DT
cord-010027-r0tl01kq	1606	13	proportion	proportion	NN
cord-010027-r0tl01kq	1606	14	of	of	IN
cord-010027-r0tl01kq	1606	15	cells	cell	NNS
cord-010027-r0tl01kq	1606	16	.	.	.
cord-010027-r0tl01kq	1607	1	Therefore	therefore	RB
cord-010027-r0tl01kq	1607	2	this	this	DT
cord-010027-r0tl01kq	1607	3	case	case	NN
cord-010027-r0tl01kq	1607	4	is	be	VBZ
cord-010027-r0tl01kq	1607	5	best	well	RBS
cord-010027-r0tl01kq	1607	6	regarded	regard	VBN
cord-010027-r0tl01kq	1607	7	as	as	IN
cord-010027-r0tl01kq	1607	8	a	a	DT
cord-010027-r0tl01kq	1607	9	composite	composite	JJ
cord-010027-r0tl01kq	1607	10	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1607	11	of	of	IN
cord-010027-r0tl01kq	1607	12	diffuse	diffuse	JJ
cord-010027-r0tl01kq	1607	13	large	large	JJ
cord-010027-r0tl01kq	1607	14	B	b	NN
cord-010027-r0tl01kq	1607	15	cell	cell	NN
cord-010027-r0tl01kq	1607	16	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1607	17	with	with	IN
cord-010027-r0tl01kq	1607	18	hairy	hairy	JJ
cord-010027-r0tl01kq	1607	19	cell	cell	NN
cord-010027-r0tl01kq	1607	20	leukemia	leukemia	NN
cord-010027-r0tl01kq	1607	21	rather	rather	RB
cord-010027-r0tl01kq	1607	22	than	than	IN
cord-010027-r0tl01kq	1607	23	blastic	blastic	JJ
cord-010027-r0tl01kq	1607	24	transformation	transformation	NN
cord-010027-r0tl01kq	1607	25	of	of	IN
cord-010027-r0tl01kq	1607	26	hairy	hairy	JJ
cord-010027-r0tl01kq	1607	27	cell	cell	NN
cord-010027-r0tl01kq	1607	28	leukemia	leukemia	NN
cord-010027-r0tl01kq	1607	29	.	.	.
cord-010027-r0tl01kq	1608	1	To	to	IN
cord-010027-r0tl01kq	1608	2	the	the	DT
cord-010027-r0tl01kq	1608	3	best	good	JJS
cord-010027-r0tl01kq	1608	4	of	of	IN
cord-010027-r0tl01kq	1608	5	our	-PRON-	PRP$
cord-010027-r0tl01kq	1608	6	knowledge	knowledge	NN
cord-010027-r0tl01kq	1608	7	,	,	,
cord-010027-r0tl01kq	1608	8	simultaneous	simultaneous	JJ
cord-010027-r0tl01kq	1608	9	occurrence	occurrence	NN
cord-010027-r0tl01kq	1608	10	of	of	IN
cord-010027-r0tl01kq	1608	11	diffuse	diffuse	JJ
cord-010027-r0tl01kq	1608	12	large	large	JJ
cord-010027-r0tl01kq	1608	13	B	b	NN
cord-010027-r0tl01kq	1608	14	cell	cell	NN
cord-010027-r0tl01kq	1608	15	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1608	16	and	and	CC
cord-010027-r0tl01kq	1608	17	hairy	hairy	JJ
cord-010027-r0tl01kq	1608	18	cell	cell	NN
cord-010027-r0tl01kq	1608	19	leukemia	leukemia	NN
cord-010027-r0tl01kq	1608	20	in	in	IN
cord-010027-r0tl01kq	1608	21	a	a	DT
cord-010027-r0tl01kq	1608	22	lymph	lymph	NN
cord-010027-r0tl01kq	1608	23	node	node	NN
cord-010027-r0tl01kq	1608	24	has	have	VBZ
cord-010027-r0tl01kq	1608	25	not	not	RB
cord-010027-r0tl01kq	1608	26	yet	yet	RB
cord-010027-r0tl01kq	1608	27	been	be	VBN
cord-010027-r0tl01kq	1608	28	reported	report	VBN
cord-010027-r0tl01kq	1608	29	in	in	IN
cord-010027-r0tl01kq	1608	30	the	the	DT
cord-010027-r0tl01kq	1608	31	literature	literature	NN
cord-010027-r0tl01kq	1608	32	.	.	.
cord-010027-r0tl01kq	1609	1	Bone	bone	NN
cord-010027-r0tl01kq	1609	2	marrow	marrow	NN
cord-010027-r0tl01kq	1609	3	examination	examination	NN
cord-010027-r0tl01kq	1609	4	by	by	IN
cord-010027-r0tl01kq	1609	5	aspirate	aspirate	NN
cord-010027-r0tl01kq	1609	6	and	and	CC
cord-010027-r0tl01kq	1609	7	trephine	trephine	NNP
cord-010027-r0tl01kq	1609	8	biopsy	biopsy	NN
cord-010027-r0tl01kq	1609	9	is	be	VBZ
cord-010027-r0tl01kq	1609	10	an	an	DT
cord-010027-r0tl01kq	1609	11	important	important	JJ
cord-010027-r0tl01kq	1609	12	haematological	haematological	JJ
cord-010027-r0tl01kq	1609	13	investigation	investigation	NN
cord-010027-r0tl01kq	1609	14	.	.	.
cord-010027-r0tl01kq	1610	1	Ideally	ideally	RB
cord-010027-r0tl01kq	1610	2	,	,	,
cord-010027-r0tl01kq	1610	3	aspirate	aspirate	VB
cord-010027-r0tl01kq	1610	4	findings	finding	NNS
cord-010027-r0tl01kq	1610	5	should	should	MD
cord-010027-r0tl01kq	1610	6	inform	inform	VB
cord-010027-r0tl01kq	1610	7	examination	examination	NN
cord-010027-r0tl01kq	1610	8	of	of	IN
cord-010027-r0tl01kq	1610	9	the	the	DT
cord-010027-r0tl01kq	1610	10	trephine	trephine	NNP
cord-010027-r0tl01kq	1610	11	biopsy	biopsy	NNP
cord-010027-r0tl01kq	1610	12	,	,	,
cord-010027-r0tl01kq	1610	13	but	but	CC
cord-010027-r0tl01kq	1610	14	if	if	IN
cord-010027-r0tl01kq	1610	15	the	the	DT
cord-010027-r0tl01kq	1610	16	two	two	CD
cord-010027-r0tl01kq	1610	17	modalities	modality	NNS
cord-010027-r0tl01kq	1610	18	are	be	VBP
cord-010027-r0tl01kq	1610	19	separate	separate	JJ
cord-010027-r0tl01kq	1610	20	the	the	DT
cord-010027-r0tl01kq	1610	21	aspirate	aspirate	NN
cord-010027-r0tl01kq	1610	22	report	report	NN
cord-010027-r0tl01kq	1610	23	can	can	MD
cord-010027-r0tl01kq	1610	24	be	be	VB
cord-010027-r0tl01kq	1610	25	delayed	delay	VBN
cord-010027-r0tl01kq	1610	26	and	and	CC
cord-010027-r0tl01kq	1610	27	histopathologists	histopathologist	NNS
cord-010027-r0tl01kq	1610	28	may	may	MD
cord-010027-r0tl01kq	1610	29	assess	assess	VB
cord-010027-r0tl01kq	1610	30	the	the	DT
cord-010027-r0tl01kq	1610	31	trephine	trephine	NNP
cord-010027-r0tl01kq	1610	32	biopsy	biopsy	NN
cord-010027-r0tl01kq	1610	33	without	without	IN
cord-010027-r0tl01kq	1610	34	being	be	VBG
cord-010027-r0tl01kq	1610	35	aware	aware	JJ
cord-010027-r0tl01kq	1610	36	of	of	IN
cord-010027-r0tl01kq	1610	37	the	the	DT
cord-010027-r0tl01kq	1610	38	aspirate	aspirate	NN
cord-010027-r0tl01kq	1610	39	findings	finding	NNS
cord-010027-r0tl01kq	1610	40	.	.	.
cord-010027-r0tl01kq	1611	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1611	2	audited	audit	VBD
cord-010027-r0tl01kq	1611	3	the	the	DT
cord-010027-r0tl01kq	1611	4	availability	availability	NN
cord-010027-r0tl01kq	1611	5	of	of	IN
cord-010027-r0tl01kq	1611	6	aspirate	aspirate	NN
cord-010027-r0tl01kq	1611	7	results	result	NNS
cord-010027-r0tl01kq	1611	8	to	to	IN
cord-010027-r0tl01kq	1611	9	the	the	DT
cord-010027-r0tl01kq	1611	10	histopathologist	histopathologist	NN
cord-010027-r0tl01kq	1611	11	examining	examine	VBG
cord-010027-r0tl01kq	1611	12	trephine	trephine	JJ
cord-010027-r0tl01kq	1611	13	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1611	14	,	,	,
cord-010027-r0tl01kq	1611	15	over	over	IN
cord-010027-r0tl01kq	1611	16	the	the	DT
cord-010027-r0tl01kq	1611	17	period	period	NN
cord-010027-r0tl01kq	1611	18	in	in	IN
cord-010027-r0tl01kq	1611	19	which	which	WDT
cord-010027-r0tl01kq	1611	20	our	-PRON-	PRP$
cord-010027-r0tl01kq	1611	21	department	department	NN
cord-010027-r0tl01kq	1611	22	implemented	implement	VBD
cord-010027-r0tl01kq	1611	23	an	an	DT
cord-010027-r0tl01kq	1611	24	integrated	integrated	JJ
cord-010027-r0tl01kq	1611	25	haematopathology	haematopathology	NN
cord-010027-r0tl01kq	1611	26	reporting	report	VBG
cord-010027-r0tl01kq	1611	27	system	system	NN
cord-010027-r0tl01kq	1611	28	.	.	.
cord-010027-r0tl01kq	1612	1	The	the	DT
cord-010027-r0tl01kq	1612	2	effects	effect	NNS
cord-010027-r0tl01kq	1612	3	on	on	IN
cord-010027-r0tl01kq	1612	4	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1612	5	concordance	concordance	NN
cord-010027-r0tl01kq	1612	6	,	,	,
cord-010027-r0tl01kq	1612	7	turnaround	turnaround	NN
cord-010027-r0tl01kq	1612	8	times	time	NNS
cord-010027-r0tl01kq	1612	9	and	and	CC
cord-010027-r0tl01kq	1612	10	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1612	11	requesting	request	VBG
cord-010027-r0tl01kq	1612	12	were	be	VBD
cord-010027-r0tl01kq	1612	13	also	also	RB
cord-010027-r0tl01kq	1612	14	assessed	assess	VBN
cord-010027-r0tl01kq	1612	15	.	.	.
cord-010027-r0tl01kq	1613	1	The	the	DT
cord-010027-r0tl01kq	1613	2	setting	setting	NN
cord-010027-r0tl01kq	1613	3	was	be	VBD
cord-010027-r0tl01kq	1613	4	a	a	DT
cord-010027-r0tl01kq	1613	5	regional	regional	JJ
cord-010027-r0tl01kq	1613	6	specialist	specialist	NN
cord-010027-r0tl01kq	1613	7	haematopathology	haematopathology	NN
cord-010027-r0tl01kq	1613	8	centre	centre	NN
cord-010027-r0tl01kq	1613	9	.	.	.
cord-010027-r0tl01kq	1614	1	Prior	prior	RB
cord-010027-r0tl01kq	1614	2	to	to	IN
cord-010027-r0tl01kq	1614	3	integration	integration	NN
cord-010027-r0tl01kq	1614	4	,	,	,
cord-010027-r0tl01kq	1614	5	a	a	DT
cord-010027-r0tl01kq	1614	6	prospective	prospective	JJ
cord-010027-r0tl01kq	1614	7	audit	audit	NN
cord-010027-r0tl01kq	1614	8	of	of	IN
cord-010027-r0tl01kq	1614	9	101	101	CD
cord-010027-r0tl01kq	1614	10	consecutive	consecutive	JJ
cord-010027-r0tl01kq	1614	11	trephine	trephine	NN
cord-010027-r0tl01kq	1614	12	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1614	13	received	receive	VBN
cord-010027-r0tl01kq	1614	14	by	by	IN
cord-010027-r0tl01kq	1614	15	a	a	DT
cord-010027-r0tl01kq	1614	16	senior	senior	JJ
cord-010027-r0tl01kq	1614	17	haematopathologist	haematopathologist	NN
cord-010027-r0tl01kq	1614	18	was	be	VBD
cord-010027-r0tl01kq	1614	19	carried	carry	VBN
cord-010027-r0tl01kq	1614	20	out	out	RP
cord-010027-r0tl01kq	1614	21	,	,	,
cord-010027-r0tl01kq	1614	22	against	against	IN
cord-010027-r0tl01kq	1614	23	standards	standard	NNS
cord-010027-r0tl01kq	1614	24	set	set	VBN
cord-010027-r0tl01kq	1614	25	by	by	IN
cord-010027-r0tl01kq	1614	26	the	the	DT
cord-010027-r0tl01kq	1614	27	International	International	NNP
cord-010027-r0tl01kq	1614	28	Committee	Committee	NNP
cord-010027-r0tl01kq	1614	29	for	for	IN
cord-010027-r0tl01kq	1614	30	Standardisation	Standardisation	NNP
cord-010027-r0tl01kq	1614	31	in	in	IN
cord-010027-r0tl01kq	1614	32	Haematology	Haematology	NNP
cord-010027-r0tl01kq	1614	33	.	.	.
cord-010027-r0tl01kq	1615	1	Data	datum	NNS
cord-010027-r0tl01kq	1615	2	were	be	VBD
cord-010027-r0tl01kq	1615	3	collected	collect	VBN
cord-010027-r0tl01kq	1615	4	from	from	IN
cord-010027-r0tl01kq	1615	5	hospital	hospital	NN
cord-010027-r0tl01kq	1615	6	computer	computer	NN
cord-010027-r0tl01kq	1615	7	systems	system	NNS
cord-010027-r0tl01kq	1615	8	.	.	.
cord-010027-r0tl01kq	1616	1	The	the	DT
cord-010027-r0tl01kq	1616	2	move	move	NN
cord-010027-r0tl01kq	1616	3	to	to	IN
cord-010027-r0tl01kq	1616	4	integrated	integrate	VBN
cord-010027-r0tl01kq	1616	5	reporting	reporting	NN
cord-010027-r0tl01kq	1616	6	involved	involve	VBD
cord-010027-r0tl01kq	1616	7	the	the	DT
cord-010027-r0tl01kq	1616	8	installation	installation	NN
cord-010027-r0tl01kq	1616	9	of	of	IN
cord-010027-r0tl01kq	1616	10	new	new	JJ
cord-010027-r0tl01kq	1616	11	software	software	NN
cord-010027-r0tl01kq	1616	12	(	(	-LRB-
cord-010027-r0tl01kq	1616	13	HiLIS	HiLIS	NNPS
cord-010027-r0tl01kq	1616	14	)	)	-RRB-
cord-010027-r0tl01kq	1616	15	to	to	TO
cord-010027-r0tl01kq	1616	16	specifically	specifically	RB
cord-010027-r0tl01kq	1616	17	handle	handle	VB
cord-010027-r0tl01kq	1616	18	integrated	integrated	JJ
cord-010027-r0tl01kq	1616	19	haematopathology	haematopathology	NN
cord-010027-r0tl01kq	1616	20	data	datum	NNS
cord-010027-r0tl01kq	1616	21	.	.	.
cord-010027-r0tl01kq	1617	1	Ten	ten	CD
cord-010027-r0tl01kq	1617	2	months	month	NNS
cord-010027-r0tl01kq	1617	3	later	later	RB
cord-010027-r0tl01kq	1617	4	,	,	,
cord-010027-r0tl01kq	1617	5	a	a	DT
cord-010027-r0tl01kq	1617	6	retrospective	retrospective	JJ
cord-010027-r0tl01kq	1617	7	analysis	analysis	NN
cord-010027-r0tl01kq	1617	8	of	of	IN
cord-010027-r0tl01kq	1617	9	a	a	DT
cord-010027-r0tl01kq	1617	10	further	further	JJ
cord-010027-r0tl01kq	1617	11	100	100	CD
cord-010027-r0tl01kq	1617	12	cases	case	NNS
cord-010027-r0tl01kq	1617	13	was	be	VBD
cord-010027-r0tl01kq	1617	14	performed	perform	VBN
cord-010027-r0tl01kq	1617	15	using	use	VBG
cord-010027-r0tl01kq	1617	16	HiLIS	HiLIS	NNPS
cord-010027-r0tl01kq	1617	17	data	datum	NNS
cord-010027-r0tl01kq	1617	18	.	.	.
cord-010027-r0tl01kq	1618	1	Prior	prior	RB
cord-010027-r0tl01kq	1618	2	to	to	IN
cord-010027-r0tl01kq	1618	3	integration	integration	NN
cord-010027-r0tl01kq	1618	4	,	,	,
cord-010027-r0tl01kq	1618	5	35	35	CD
cord-010027-r0tl01kq	1618	6	%	%	NN
cord-010027-r0tl01kq	1618	7	of	of	IN
cord-010027-r0tl01kq	1618	8	aspirates	aspirate	NNS
cord-010027-r0tl01kq	1618	9	were	be	VBD
cord-010027-r0tl01kq	1618	10	reported	report	VBN
cord-010027-r0tl01kq	1618	11	within	within	IN
cord-010027-r0tl01kq	1618	12	3	3	CD
cord-010027-r0tl01kq	1618	13	days	day	NNS
cord-010027-r0tl01kq	1618	14	,	,	,
cord-010027-r0tl01kq	1618	15	and	and	CC
cord-010027-r0tl01kq	1618	16	access	access	VB
cord-010027-r0tl01kq	1618	17	to	to	IN
cord-010027-r0tl01kq	1618	18	the	the	DT
cord-010027-r0tl01kq	1618	19	aspirate	aspirate	NN
cord-010027-r0tl01kq	1618	20	report	report	NN
cord-010027-r0tl01kq	1618	21	was	be	VBD
cord-010027-r0tl01kq	1618	22	available	available	JJ
cord-010027-r0tl01kq	1618	23	at	at	IN
cord-010027-r0tl01kq	1618	24	time	time	NN
cord-010027-r0tl01kq	1618	25	of	of	IN
cord-010027-r0tl01kq	1618	26	examination	examination	NN
cord-010027-r0tl01kq	1618	27	for	for	IN
cord-010027-r0tl01kq	1618	28	61	61	CD
cord-010027-r0tl01kq	1618	29	%	%	NN
cord-010027-r0tl01kq	1618	30	of	of	IN
cord-010027-r0tl01kq	1618	31	trephine	trephine	NN
cord-010027-r0tl01kq	1618	32	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1618	33	.	.	.
cord-010027-r0tl01kq	1619	1	After	after	IN
cord-010027-r0tl01kq	1619	2	integration	integration	NN
cord-010027-r0tl01kq	1619	3	,	,	,
cord-010027-r0tl01kq	1619	4	96	96	CD
cord-010027-r0tl01kq	1619	5	%	%	NN
cord-010027-r0tl01kq	1619	6	of	of	IN
cord-010027-r0tl01kq	1619	7	aspirates	aspirate	NNS
cord-010027-r0tl01kq	1619	8	were	be	VBD
cord-010027-r0tl01kq	1619	9	reported	report	VBN
cord-010027-r0tl01kq	1619	10	within	within	IN
cord-010027-r0tl01kq	1619	11	3	3	CD
cord-010027-r0tl01kq	1619	12	days	day	NNS
cord-010027-r0tl01kq	1619	13	,	,	,
cord-010027-r0tl01kq	1619	14	and	and	CC
cord-010027-r0tl01kq	1619	15	reports	report	NNS
cord-010027-r0tl01kq	1619	16	were	be	VBD
cord-010027-r0tl01kq	1619	17	available	available	JJ
cord-010027-r0tl01kq	1619	18	at	at	IN
cord-010027-r0tl01kq	1619	19	time	time	NN
cord-010027-r0tl01kq	1619	20	of	of	IN
cord-010027-r0tl01kq	1619	21	examination	examination	NN
cord-010027-r0tl01kq	1619	22	for	for	IN
cord-010027-r0tl01kq	1619	23	100	100	CD
cord-010027-r0tl01kq	1619	24	%	%	NN
cord-010027-r0tl01kq	1619	25	of	of	IN
cord-010027-r0tl01kq	1619	26	trephine	trephine	NN
cord-010027-r0tl01kq	1619	27	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1619	28	.	.	.
cord-010027-r0tl01kq	1620	1	Diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1620	2	concordance	concordance	NN
cord-010027-r0tl01kq	1620	3	was	be	VBD
cord-010027-r0tl01kq	1620	4	72	72	CD
cord-010027-r0tl01kq	1620	5	%	%	NN
cord-010027-r0tl01kq	1620	6	initially	initially	RB
cord-010027-r0tl01kq	1620	7	,	,	,
cord-010027-r0tl01kq	1620	8	and	and	CC
cord-010027-r0tl01kq	1620	9	100	100	CD
cord-010027-r0tl01kq	1620	10	%	%	NN
cord-010027-r0tl01kq	1620	11	after	after	IN
cord-010027-r0tl01kq	1620	12	integration	integration	NN
cord-010027-r0tl01kq	1620	13	.	.	.
cord-010027-r0tl01kq	1621	1	The	the	DT
cord-010027-r0tl01kq	1621	2	mean	mean	JJ
cord-010027-r0tl01kq	1621	3	number	number	NN
cord-010027-r0tl01kq	1621	4	of	of	IN
cord-010027-r0tl01kq	1621	5	immunostains	immunostain	NNS
cord-010027-r0tl01kq	1621	6	requested	request	VBN
cord-010027-r0tl01kq	1621	7	per	per	IN
cord-010027-r0tl01kq	1621	8	case	case	NN
cord-010027-r0tl01kq	1621	9	was	be	VBD
cord-010027-r0tl01kq	1621	10	unchanged	unchanged	JJ
cord-010027-r0tl01kq	1621	11	(	(	-LRB-
cord-010027-r0tl01kq	1621	12	5.9	5.9	CD
cord-010027-r0tl01kq	1621	13	vs	vs	IN
cord-010027-r0tl01kq	1621	14	5.7	5.7	CD
cord-010027-r0tl01kq	1621	15	)	)	-RRB-
cord-010027-r0tl01kq	1621	16	.	.	.
cord-010027-r0tl01kq	1622	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1622	2	findings	finding	NNS
cord-010027-r0tl01kq	1622	3	show	show	VBP
cord-010027-r0tl01kq	1622	4	integrated	integrated	JJ
cord-010027-r0tl01kq	1622	5	reporting	reporting	NN
cord-010027-r0tl01kq	1622	6	has	have	VBZ
cord-010027-r0tl01kq	1622	7	markedly	markedly	RB
cord-010027-r0tl01kq	1622	8	increased	increase	VBN
cord-010027-r0tl01kq	1622	9	the	the	DT
cord-010027-r0tl01kq	1622	10	availability	availability	NN
cord-010027-r0tl01kq	1622	11	of	of	IN
cord-010027-r0tl01kq	1622	12	aspirate	aspirate	NN
cord-010027-r0tl01kq	1622	13	reports	report	NNS
cord-010027-r0tl01kq	1622	14	to	to	IN
cord-010027-r0tl01kq	1622	15	the	the	DT
cord-010027-r0tl01kq	1622	16	histopathologist	histopathologist	NN
cord-010027-r0tl01kq	1622	17	,	,	,
cord-010027-r0tl01kq	1622	18	and	and	CC
cord-010027-r0tl01kq	1622	19	improved	improve	VBN
cord-010027-r0tl01kq	1622	20	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1622	21	concordance	concordance	NN
cord-010027-r0tl01kq	1622	22	.	.	.
cord-010027-r0tl01kq	1623	1	This	this	DT
cord-010027-r0tl01kq	1623	2	new	new	JJ
cord-010027-r0tl01kq	1623	3	model	model	NN
cord-010027-r0tl01kq	1623	4	benefits	benefit	VBZ
cord-010027-r0tl01kq	1623	5	the	the	DT
cord-010027-r0tl01kq	1623	6	haematologist	haematologist	NN
cord-010027-r0tl01kq	1623	7	,	,	,
cord-010027-r0tl01kq	1623	8	histopathologist	histopathologist	NN
cord-010027-r0tl01kq	1623	9	and	and	CC
cord-010027-r0tl01kq	1623	10	patient	patient	JJ
cord-010027-r0tl01kq	1623	11	.	.	.
cord-010027-r0tl01kq	1624	1	Introduction	introduction	NN
cord-010027-r0tl01kq	1624	2	:	:	:
cord-010027-r0tl01kq	1625	1	Clonality	clonality	NN
cord-010027-r0tl01kq	1625	2	studies	study	NNS
cord-010027-r0tl01kq	1625	3	are	be	VBP
cord-010027-r0tl01kq	1625	4	carried	carry	VBN
cord-010027-r0tl01kq	1625	5	out	out	RP
cord-010027-r0tl01kq	1625	6	when	when	WRB
cord-010027-r0tl01kq	1625	7	the	the	DT
cord-010027-r0tl01kq	1625	8	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1625	9	of	of	IN
cord-010027-r0tl01kq	1625	10	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1625	11	is	be	VBZ
cord-010027-r0tl01kq	1625	12	particularly	particularly	RB
cord-010027-r0tl01kq	1625	13	challenging	challenging	JJ
cord-010027-r0tl01kq	1625	14	.	.	.
cord-010027-r0tl01kq	1626	1	The	the	DT
cord-010027-r0tl01kq	1626	2	detection	detection	NN
cord-010027-r0tl01kq	1626	3	of	of	IN
cord-010027-r0tl01kq	1626	4	clonality	clonality	NN
cord-010027-r0tl01kq	1626	5	in	in	IN
cord-010027-r0tl01kq	1626	6	lymphoproliferative	lymphoproliferative	JJ
cord-010027-r0tl01kq	1626	7	lesions	lesion	NNS
cord-010027-r0tl01kq	1626	8	suspicious	suspicious	JJ
cord-010027-r0tl01kq	1626	9	for	for	IN
cord-010027-r0tl01kq	1626	10	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1626	11	can	can	MD
cord-010027-r0tl01kq	1626	12	be	be	VB
cord-010027-r0tl01kq	1626	13	a	a	DT
cord-010027-r0tl01kq	1626	14	valuable	valuable	JJ
cord-010027-r0tl01kq	1626	15	supplementary	supplementary	JJ
cord-010027-r0tl01kq	1626	16	tool	tool	NN
cord-010027-r0tl01kq	1626	17	as	as	IN
cord-010027-r0tl01kq	1626	18	it	-PRON-	PRP
cord-010027-r0tl01kq	1626	19	has	have	VBZ
cord-010027-r0tl01kq	1626	20	a	a	DT
cord-010027-r0tl01kq	1626	21	high	high	JJ
cord-010027-r0tl01kq	1626	22	positive	positive	JJ
cord-010027-r0tl01kq	1626	23	predictive	predictive	JJ
cord-010027-r0tl01kq	1626	24	value	value	NN
cord-010027-r0tl01kq	1626	25	.	.	.
cord-010027-r0tl01kq	1627	1	Clonal	Clonal	NNP
cord-010027-r0tl01kq	1627	2	studies	study	NNS
cord-010027-r0tl01kq	1627	3	can	can	MD
cord-010027-r0tl01kq	1627	4	also	also	RB
cord-010027-r0tl01kq	1627	5	help	help	VB
cord-010027-r0tl01kq	1627	6	to	to	TO
cord-010027-r0tl01kq	1627	7	distinguish	distinguish	VB
cord-010027-r0tl01kq	1627	8	recurrent	recurrent	JJ
cord-010027-r0tl01kq	1627	9	or	or	CC
cord-010027-r0tl01kq	1627	10	residual	residual	JJ
cord-010027-r0tl01kq	1627	11	disease	disease	NN
cord-010027-r0tl01kq	1627	12	from	from	IN
cord-010027-r0tl01kq	1627	13	reactive	reactive	JJ
cord-010027-r0tl01kq	1627	14	inflammation	inflammation	NN
cord-010027-r0tl01kq	1627	15	.	.	.
cord-010027-r0tl01kq	1628	1	However	however	RB
cord-010027-r0tl01kq	1628	2	false	false	JJ
cord-010027-r0tl01kq	1628	3	positive	positive	JJ
cord-010027-r0tl01kq	1628	4	and	and	CC
cord-010027-r0tl01kq	1628	5	negatives	negative	NNS
cord-010027-r0tl01kq	1628	6	are	be	VBP
cord-010027-r0tl01kq	1628	7	common	common	JJ
cord-010027-r0tl01kq	1628	8	and	and	CC
cord-010027-r0tl01kq	1628	9	can	can	MD
cord-010027-r0tl01kq	1628	10	be	be	VB
cord-010027-r0tl01kq	1628	11	attributable	attributable	JJ
cord-010027-r0tl01kq	1628	12	to	to	IN
cord-010027-r0tl01kq	1628	13	several	several	JJ
cord-010027-r0tl01kq	1628	14	factors	factor	NNS
cord-010027-r0tl01kq	1628	15	,	,	,
cord-010027-r0tl01kq	1628	16	including	include	VBG
cord-010027-r0tl01kq	1628	17	poor	poor	JJ
cord-010027-r0tl01kq	1628	18	DNA	dna	NN
cord-010027-r0tl01kq	1628	19	quality	quality	NN
cord-010027-r0tl01kq	1628	20	.	.	.
cord-010027-r0tl01kq	1629	1	Methods	method	NNS
cord-010027-r0tl01kq	1629	2	:	:	:
cord-010027-r0tl01kq	1630	1	206	206	CD
cord-010027-r0tl01kq	1630	2	cases	case	NNS
cord-010027-r0tl01kq	1630	3	reported	report	VBN
cord-010027-r0tl01kq	1630	4	over	over	IN
cord-010027-r0tl01kq	1630	5	a	a	DT
cord-010027-r0tl01kq	1630	6	six	six	CD
cord-010027-r0tl01kq	1630	7	month	month	NN
cord-010027-r0tl01kq	1630	8	period	period	NN
cord-010027-r0tl01kq	1630	9	(	(	-LRB-
cord-010027-r0tl01kq	1630	10	Jun	Jun	NNP
cord-010027-r0tl01kq	1630	11	-	-	HYPH
cord-010027-r0tl01kq	1630	12	Nov	Nov	NNP
cord-010027-r0tl01kq	1630	13	2014	2014	CD
cord-010027-r0tl01kq	1630	14	)	)	-RRB-
cord-010027-r0tl01kq	1630	15	were	be	VBD
cord-010027-r0tl01kq	1630	16	retrospectively	retrospectively	RB
cord-010027-r0tl01kq	1630	17	reviewed	review	VBN
cord-010027-r0tl01kq	1630	18	,	,	,
cord-010027-r0tl01kq	1630	19	62	62	CD
cord-010027-r0tl01kq	1630	20	%	%	NN
cord-010027-r0tl01kq	1630	21	of	of	IN
cord-010027-r0tl01kq	1630	22	which	which	WDT
cord-010027-r0tl01kq	1630	23	were	be	VBD
cord-010027-r0tl01kq	1630	24	referral	referral	JJ
cord-010027-r0tl01kq	1630	25	cases	case	NNS
cord-010027-r0tl01kq	1630	26	.	.	.
cord-010027-r0tl01kq	1631	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1631	2	investigated	investigate	VBD
cord-010027-r0tl01kq	1631	3	various	various	JJ
cord-010027-r0tl01kq	1631	4	aspects	aspect	NNS
cord-010027-r0tl01kq	1631	5	of	of	IN
cord-010027-r0tl01kq	1631	6	clonality	clonality	NN
cord-010027-r0tl01kq	1631	7	studies	study	NNS
cord-010027-r0tl01kq	1631	8	;	;	:
cord-010027-r0tl01kq	1631	9	including	include	VBG
cord-010027-r0tl01kq	1631	10	DNA	dna	NN
cord-010027-r0tl01kq	1631	11	quality	quality	NN
cord-010027-r0tl01kq	1631	12	,	,	,
cord-010027-r0tl01kq	1631	13	fixation	fixation	NN
cord-010027-r0tl01kq	1631	14	method	method	NN
cord-010027-r0tl01kq	1631	15	,	,	,
cord-010027-r0tl01kq	1631	16	clinical	clinical	JJ
cord-010027-r0tl01kq	1631	17	information	information	NN
cord-010027-r0tl01kq	1631	18	provided	provide	VBN
cord-010027-r0tl01kq	1631	19	and	and	CC
cord-010027-r0tl01kq	1631	20	correlation	correlation	NN
cord-010027-r0tl01kq	1631	21	between	between	IN
cord-010027-r0tl01kq	1631	22	the	the	DT
cord-010027-r0tl01kq	1631	23	morphological	morphological	JJ
cord-010027-r0tl01kq	1631	24	/	/	SYM
cord-010027-r0tl01kq	1631	25	immunophenotypical	immunophenotypical	JJ
cord-010027-r0tl01kq	1631	26	findings	finding	NNS
cord-010027-r0tl01kq	1631	27	and	and	CC
cord-010027-r0tl01kq	1631	28	clonality	clonality	NN
cord-010027-r0tl01kq	1631	29	results	result	NNS
cord-010027-r0tl01kq	1631	30	using	use	VBG
cord-010027-r0tl01kq	1631	31	Euroclonality	Euroclonality	NNP
cord-010027-r0tl01kq	1631	32	/	/	SYM
cord-010027-r0tl01kq	1631	33	BIOMED-2	biomed-2	CC
cord-010027-r0tl01kq	1631	34	primers	primer	NNS
cord-010027-r0tl01kq	1631	35	(	(	-LRB-
cord-010027-r0tl01kq	1631	36	IgH	igh	NN
cord-010027-r0tl01kq	1631	37	,	,	,
cord-010027-r0tl01kq	1631	38	IgK	igk	NN
cord-010027-r0tl01kq	1631	39	,	,	,
cord-010027-r0tl01kq	1631	40	TCR	TCR	NNP
cord-010027-r0tl01kq	1631	41	-	-	HYPH
cord-010027-r0tl01kq	1631	42	Β	Β	NNP
cord-010027-r0tl01kq	1631	43	and	and	CC
cord-010027-r0tl01kq	1631	44	gamma	gamma	NN
cord-010027-r0tl01kq	1631	45	-	-	HYPH
cord-010027-r0tl01kq	1631	46	delta	delta	NN
cord-010027-r0tl01kq	1631	47	)	)	-RRB-
cord-010027-r0tl01kq	1631	48	.	.	.
cord-010027-r0tl01kq	1632	1	Results	result	NNS
cord-010027-r0tl01kq	1632	2	:	:	:
cord-010027-r0tl01kq	1632	3	166	166	CD
cord-010027-r0tl01kq	1632	4	(	(	-LRB-
cord-010027-r0tl01kq	1632	5	81	81	CD
cord-010027-r0tl01kq	1632	6	%	%	NN
cord-010027-r0tl01kq	1632	7	)	)	-RRB-
cord-010027-r0tl01kq	1632	8	had	have	VBD
cord-010027-r0tl01kq	1632	9	adequate	adequate	JJ
cord-010027-r0tl01kq	1632	10	DNA	dna	NN
cord-010027-r0tl01kq	1632	11	quality	quality	NN
cord-010027-r0tl01kq	1632	12	,	,	,
cord-010027-r0tl01kq	1632	13	29	29	CD
cord-010027-r0tl01kq	1632	14	(	(	-LRB-
cord-010027-r0tl01kq	1632	15	14	14	CD
cord-010027-r0tl01kq	1632	16	%	%	NN
cord-010027-r0tl01kq	1632	17	)	)	-RRB-
cord-010027-r0tl01kq	1633	1	poor	poor	JJ
cord-010027-r0tl01kq	1633	2	DNA	DNA	NNP
cord-010027-r0tl01kq	1633	3	and	and	CC
cord-010027-r0tl01kq	1633	4	11	11	CD
cord-010027-r0tl01kq	1633	5	(	(	-LRB-
cord-010027-r0tl01kq	1633	6	5	5	CD
cord-010027-r0tl01kq	1633	7	%	%	NN
cord-010027-r0tl01kq	1633	8	)	)	-RRB-
cord-010027-r0tl01kq	1633	9	had	have	VBD
cord-010027-r0tl01kq	1633	10	inadequate	inadequate	JJ
cord-010027-r0tl01kq	1633	11	DNA	dna	NN
cord-010027-r0tl01kq	1633	12	quality	quality	NN
cord-010027-r0tl01kq	1633	13	.	.	.
cord-010027-r0tl01kq	1634	1	External	external	JJ
cord-010027-r0tl01kq	1634	2	cases	case	NNS
cord-010027-r0tl01kq	1634	3	had	have	VBD
cord-010027-r0tl01kq	1634	4	better	well	JJR
cord-010027-r0tl01kq	1634	5	DNA	dna	NN
cord-010027-r0tl01kq	1634	6	quality	quality	NN
cord-010027-r0tl01kq	1634	7	in	in	IN
cord-010027-r0tl01kq	1634	8	the	the	DT
cord-010027-r0tl01kq	1634	9	majority	majority	NN
cord-010027-r0tl01kq	1634	10	of	of	IN
cord-010027-r0tl01kq	1634	11	cases	case	NNS
cord-010027-r0tl01kq	1634	12	.	.	.
cord-010027-r0tl01kq	1635	1	Clinical	clinical	JJ
cord-010027-r0tl01kq	1635	2	information	information	NN
cord-010027-r0tl01kq	1635	3	was	be	VBD
cord-010027-r0tl01kq	1635	4	provided	provide	VBN
cord-010027-r0tl01kq	1635	5	in	in	IN
cord-010027-r0tl01kq	1635	6	75	75	CD
cord-010027-r0tl01kq	1635	7	%	%	NN
cord-010027-r0tl01kq	1635	8	of	of	IN
cord-010027-r0tl01kq	1635	9	local	local	JJ
cord-010027-r0tl01kq	1635	10	cases	case	NNS
cord-010027-r0tl01kq	1635	11	and	and	CC
cord-010027-r0tl01kq	1635	12	53	53	CD
cord-010027-r0tl01kq	1635	13	%	%	NN
cord-010027-r0tl01kq	1635	14	of	of	IN
cord-010027-r0tl01kq	1635	15	external	external	JJ
cord-010027-r0tl01kq	1635	16	cases	case	NNS
cord-010027-r0tl01kq	1635	17	.	.	.
cord-010027-r0tl01kq	1636	1	In	in	IN
cord-010027-r0tl01kq	1636	2	56	56	CD
cord-010027-r0tl01kq	1636	3	%	%	NN
cord-010027-r0tl01kq	1636	4	of	of	IN
cord-010027-r0tl01kq	1636	5	cases	case	NNS
cord-010027-r0tl01kq	1636	6	clonality	clonality	NN
cord-010027-r0tl01kq	1636	7	results	result	NNS
cord-010027-r0tl01kq	1636	8	supported	support	VBD
cord-010027-r0tl01kq	1636	9	the	the	DT
cord-010027-r0tl01kq	1636	10	initial	initial	JJ
cord-010027-r0tl01kq	1636	11	histological	histological	JJ
cord-010027-r0tl01kq	1636	12	report	report	NN
cord-010027-r0tl01kq	1636	13	.	.	.
cord-010027-r0tl01kq	1637	1	9	9	CD
cord-010027-r0tl01kq	1637	2	cases	case	NNS
cord-010027-r0tl01kq	1637	3	showed	show	VBD
cord-010027-r0tl01kq	1637	4	clonal	clonal	JJ
cord-010027-r0tl01kq	1637	5	expansion	expansion	NN
cord-010027-r0tl01kq	1637	6	despite	despite	IN
cord-010027-r0tl01kq	1637	7	a	a	DT
cord-010027-r0tl01kq	1637	8	benign	benign	JJ
cord-010027-r0tl01kq	1637	9	process	process	NN
cord-010027-r0tl01kq	1637	10	on	on	IN
cord-010027-r0tl01kq	1637	11	histology	histology	NN
cord-010027-r0tl01kq	1637	12	.	.	.
cord-010027-r0tl01kq	1638	1	21	21	CD
cord-010027-r0tl01kq	1638	2	suspected	suspect	VBN
cord-010027-r0tl01kq	1638	3	cases	case	NNS
cord-010027-r0tl01kq	1638	4	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1638	5	(	(	-LRB-
cord-010027-r0tl01kq	1638	6	13	13	CD
cord-010027-r0tl01kq	1638	7	B	B	NNP
cord-010027-r0tl01kq	1638	8	-	-	HYPH
cord-010027-r0tl01kq	1638	9	NHL	NHL	NNP
cord-010027-r0tl01kq	1638	10	and	and	CC
cord-010027-r0tl01kq	1638	11	8	8	CD
cord-010027-r0tl01kq	1638	12	T	T	NNP
cord-010027-r0tl01kq	1638	13	-	-	HYPH
cord-010027-r0tl01kq	1638	14	NHL	NHL	NNP
cord-010027-r0tl01kq	1638	15	)	)	-RRB-
cord-010027-r0tl01kq	1638	16	showed	show	VBD
cord-010027-r0tl01kq	1638	17	no	no	DT
cord-010027-r0tl01kq	1638	18	clonality	clonality	NN
cord-010027-r0tl01kq	1638	19	,	,	,
cord-010027-r0tl01kq	1638	20	8	8	CD
cord-010027-r0tl01kq	1638	21	of	of	IN
cord-010027-r0tl01kq	1638	22	which	which	WDT
cord-010027-r0tl01kq	1638	23	yielded	yield	VBD
cord-010027-r0tl01kq	1638	24	poor	poor	JJ
cord-010027-r0tl01kq	1638	25	DNA	dna	NN
cord-010027-r0tl01kq	1638	26	quality	quality	NN
cord-010027-r0tl01kq	1638	27	.	.	.
cord-010027-r0tl01kq	1639	1	Skin	skin	NN
cord-010027-r0tl01kq	1639	2	cases	case	NNS
cord-010027-r0tl01kq	1639	3	although	although	IN
cord-010027-r0tl01kq	1639	4	had	have	VBD
cord-010027-r0tl01kq	1639	5	good	good	JJ
cord-010027-r0tl01kq	1639	6	DNA	dna	NN
cord-010027-r0tl01kq	1639	7	quality	quality	NN
cord-010027-r0tl01kq	1639	8	,	,	,
cord-010027-r0tl01kq	1639	9	usually	usually	RB
cord-010027-r0tl01kq	1639	10	had	have	VBD
cord-010027-r0tl01kq	1639	11	low	low	JJ
cord-010027-r0tl01kq	1639	12	number	number	NN
cord-010027-r0tl01kq	1639	13	of	of	IN
cord-010027-r0tl01kq	1639	14	neoplastic	neoplastic	JJ
cord-010027-r0tl01kq	1639	15	cells	cell	NNS
cord-010027-r0tl01kq	1639	16	resulting	result	VBG
cord-010027-r0tl01kq	1639	17	in	in	IN
cord-010027-r0tl01kq	1639	18	poor	poor	JJ
cord-010027-r0tl01kq	1639	19	PCR	PCR	NNP
cord-010027-r0tl01kq	1639	20	products	product	NNS
cord-010027-r0tl01kq	1639	21	.	.	.
cord-010027-r0tl01kq	1640	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1640	2	:	:	:
cord-010027-r0tl01kq	1641	1	DNA	dna	NN
cord-010027-r0tl01kq	1641	2	quality	quality	NN
cord-010027-r0tl01kq	1641	3	is	be	VBZ
cord-010027-r0tl01kq	1641	4	very	very	RB
cord-010027-r0tl01kq	1641	5	variable	variable	JJ
cord-010027-r0tl01kq	1641	6	and	and	CC
cord-010027-r0tl01kq	1641	7	clinical	clinical	JJ
cord-010027-r0tl01kq	1641	8	information	information	NN
cord-010027-r0tl01kq	1641	9	is	be	VBZ
cord-010027-r0tl01kq	1641	10	often	often	RB
cord-010027-r0tl01kq	1641	11	not	not	RB
cord-010027-r0tl01kq	1641	12	provided	provide	VBN
cord-010027-r0tl01kq	1641	13	precluding	preclude	VBG
cord-010027-r0tl01kq	1641	14	adequate	adequate	JJ
cord-010027-r0tl01kq	1641	15	assessment	assessment	NN
cord-010027-r0tl01kq	1641	16	of	of	IN
cord-010027-r0tl01kq	1641	17	clonality	clonality	NN
cord-010027-r0tl01kq	1641	18	findings	finding	NNS
cord-010027-r0tl01kq	1641	19	.	.	.
cord-010027-r0tl01kq	1642	1	DNA	DNA	NNP
cord-010027-r0tl01kq	1642	2	was	be	VBD
cord-010027-r0tl01kq	1642	3	worse	bad	JJR
cord-010027-r0tl01kq	1642	4	locally	locally	RB
cord-010027-r0tl01kq	1642	5	(	(	-LRB-
cord-010027-r0tl01kq	1642	6	decalcified	decalcify	VBN
cord-010027-r0tl01kq	1642	7	marrow	marrow	NN
cord-010027-r0tl01kq	1642	8	trephines	trephine	NNS
cord-010027-r0tl01kq	1642	9	using	use	VBG
cord-010027-r0tl01kq	1642	10	formic	formic	JJ
cord-010027-r0tl01kq	1642	11	acid	acid	NN
cord-010027-r0tl01kq	1642	12	and	and	CC
cord-010027-r0tl01kq	1642	13	Peloris	Peloris	NNP
cord-010027-r0tl01kq	1642	14	system	system	NN
cord-010027-r0tl01kq	1642	15	with	with	IN
cord-010027-r0tl01kq	1642	16	high	high	JJ
cord-010027-r0tl01kq	1642	17	temperatures	temperature	NNS
cord-010027-r0tl01kq	1642	18	that	that	WDT
cord-010027-r0tl01kq	1642	19	can	can	MD
cord-010027-r0tl01kq	1642	20	cause	cause	VB
cord-010027-r0tl01kq	1642	21	DNA	dna	NN
cord-010027-r0tl01kq	1642	22	degradation	degradation	NN
cord-010027-r0tl01kq	1642	23	)	)	-RRB-
cord-010027-r0tl01kq	1642	24	.	.	.
cord-010027-r0tl01kq	1643	1	Standardisation	standardisation	NN
cord-010027-r0tl01kq	1643	2	of	of	IN
cord-010027-r0tl01kq	1643	3	fixation	fixation	NN
cord-010027-r0tl01kq	1643	4	methods	method	NNS
cord-010027-r0tl01kq	1643	5	and	and	CC
cord-010027-r0tl01kq	1643	6	interpretation	interpretation	NN
cord-010027-r0tl01kq	1643	7	of	of	IN
cord-010027-r0tl01kq	1643	8	peaks/	peaks/	CD
cord-010027-r0tl01kq	1643	9	bands	band	NNS
cord-010027-r0tl01kq	1643	10	in	in	IN
cord-010027-r0tl01kq	1643	11	the	the	DT
cord-010027-r0tl01kq	1643	12	clinical	clinical	JJ
cord-010027-r0tl01kq	1643	13	context	context	NN
cord-010027-r0tl01kq	1643	14	of	of	IN
cord-010027-r0tl01kq	1643	15	the	the	DT
cord-010027-r0tl01kq	1643	16	patient	patient	NN
cord-010027-r0tl01kq	1643	17	is	be	VBZ
cord-010027-r0tl01kq	1643	18	essential	essential	JJ
cord-010027-r0tl01kq	1643	19	for	for	IN
cord-010027-r0tl01kq	1643	20	clonality	clonality	NN
cord-010027-r0tl01kq	1643	21	to	to	TO
cord-010027-r0tl01kq	1643	22	be	be	VB
cord-010027-r0tl01kq	1643	23	informative	informative	JJ
cord-010027-r0tl01kq	1643	24	.	.	.
cord-010027-r0tl01kq	1644	1	Kikuchi	Kikuchi	NNP
cord-010027-r0tl01kq	1644	2	-	-	HYPH
cord-010027-r0tl01kq	1644	3	Fujimoto	Fujimoto	NNP
cord-010027-r0tl01kq	1644	4	Disease	Disease	NNP
cord-010027-r0tl01kq	1644	5	:	:	:
cord-010027-r0tl01kq	1645	1	A	a	DT
cord-010027-r0tl01kq	1645	2	Novel	Novel	NNP
cord-010027-r0tl01kq	1645	3	Diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1645	4	by	by	IN
cord-010027-r0tl01kq	1645	5	Transbronchial	Transbronchial	NNP
cord-010027-r0tl01kq	1645	6	Biopsy	Biopsy	NNP
cord-010027-r0tl01kq	1645	7	of	of	IN
cord-010027-r0tl01kq	1645	8	Mediastinal	Mediastinal	NNP
cord-010027-r0tl01kq	1645	9	Lymphadenopathy	Lymphadenopathy	NNP
cord-010027-r0tl01kq	1645	10	P	P	NNP
cord-010027-r0tl01kq	1645	11	PM	pm	NN
cord-010027-r0tl01kq	1645	12	Ellery	Ellery	NNP
cord-010027-r0tl01kq	1645	13	;	;	:
cord-010027-r0tl01kq	1645	14	N	N	NNP
cord-010027-r0tl01kq	1645	15	Archard	Archard	NNP
cord-010027-r0tl01kq	1645	16	;	;	:
cord-010027-r0tl01kq	1645	17	A	a	DT
cord-010027-r0tl01kq	1645	18	Ramsay	Ramsay	NNP
cord-010027-r0tl01kq	1645	19	UCL	UCL	NNP
cord-010027-r0tl01kq	1645	20	Hospitals	Hospitals	NNPS
cord-010027-r0tl01kq	1645	21	NHS	NHS	NNP
cord-010027-r0tl01kq	1645	22	Foundation	Foundation	NNP
cord-010027-r0tl01kq	1645	23	Trust	Trust	NNP
cord-010027-r0tl01kq	1645	24	,	,	,
cord-010027-r0tl01kq	1645	25	London	London	NNP
cord-010027-r0tl01kq	1645	26	,	,	,
cord-010027-r0tl01kq	1646	1	UK	UK	NNP
cord-010027-r0tl01kq	1646	2	Objectives	Objectives	NNP
cord-010027-r0tl01kq	1646	3	:	:	:
cord-010027-r0tl01kq	1646	4	Kikuchi	Kikuchi	NNP
cord-010027-r0tl01kq	1646	5	-	-	HYPH
cord-010027-r0tl01kq	1646	6	Fujimoto	Fujimoto	NNP
cord-010027-r0tl01kq	1646	7	disease	disease	NN
cord-010027-r0tl01kq	1646	8	(	(	-LRB-
cord-010027-r0tl01kq	1646	9	KFD	KFD	NNP
cord-010027-r0tl01kq	1646	10	)	)	-RRB-
cord-010027-r0tl01kq	1646	11	is	be	VBZ
cord-010027-r0tl01kq	1646	12	a	a	DT
cord-010027-r0tl01kq	1646	13	rare	rare	JJ
cord-010027-r0tl01kq	1646	14	,	,	,
cord-010027-r0tl01kq	1646	15	self	self	NN
cord-010027-r0tl01kq	1646	16	-	-	HYPH
cord-010027-r0tl01kq	1646	17	limiting	limit	VBG
cord-010027-r0tl01kq	1646	18	form	form	NN
cord-010027-r0tl01kq	1646	19	of	of	IN
cord-010027-r0tl01kq	1646	20	necrotising	necrotise	VBG
cord-010027-r0tl01kq	1646	21	lymphadenitis	lymphadenitis	NNP
cord-010027-r0tl01kq	1646	22	that	that	WDT
cord-010027-r0tl01kq	1646	23	most	most	RBS
cord-010027-r0tl01kq	1646	24	commonly	commonly	RB
cord-010027-r0tl01kq	1646	25	affects	affect	VBZ
cord-010027-r0tl01kq	1646	26	young	young	JJ
cord-010027-r0tl01kq	1646	27	Asian	asian	JJ
cord-010027-r0tl01kq	1646	28	women	woman	NNS
cord-010027-r0tl01kq	1646	29	,	,	,
cord-010027-r0tl01kq	1646	30	and	and	CC
cord-010027-r0tl01kq	1646	31	classically	classically	RB
cord-010027-r0tl01kq	1646	32	presents	present	VBZ
cord-010027-r0tl01kq	1646	33	with	with	IN
cord-010027-r0tl01kq	1646	34	fever	fever	NN
cord-010027-r0tl01kq	1646	35	,	,	,
cord-010027-r0tl01kq	1646	36	malaise	malaise	NN
cord-010027-r0tl01kq	1646	37	and	and	CC
cord-010027-r0tl01kq	1646	38	lymphadenopathy	lymphadenopathy	JJ
cord-010027-r0tl01kq	1646	39	.	.	.
cord-010027-r0tl01kq	1647	1	The	the	DT
cord-010027-r0tl01kq	1647	2	cervical	cervical	JJ
cord-010027-r0tl01kq	1647	3	lymph	lymph	NN
cord-010027-r0tl01kq	1647	4	nodes	node	NNS
cord-010027-r0tl01kq	1647	5	are	be	VBP
cord-010027-r0tl01kq	1647	6	involved	involve	VBN
cord-010027-r0tl01kq	1647	7	in	in	IN
cord-010027-r0tl01kq	1647	8	around	around	IN
cord-010027-r0tl01kq	1647	9	85	85	CD
cord-010027-r0tl01kq	1647	10	%	%	NN
cord-010027-r0tl01kq	1647	11	of	of	IN
cord-010027-r0tl01kq	1647	12	cases	case	NNS
cord-010027-r0tl01kq	1647	13	,	,	,
cord-010027-r0tl01kq	1647	14	with	with	IN
cord-010027-r0tl01kq	1647	15	other	other	JJ
cord-010027-r0tl01kq	1647	16	sites	site	NNS
cord-010027-r0tl01kq	1647	17	rarely	rarely	RB
cord-010027-r0tl01kq	1647	18	involved	involve	VBN
cord-010027-r0tl01kq	1647	19	.	.	.
cord-010027-r0tl01kq	1648	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1648	2	report	report	VBP
cord-010027-r0tl01kq	1648	3	an	an	DT
cord-010027-r0tl01kq	1648	4	unusual	unusual	JJ
cord-010027-r0tl01kq	1648	5	case	case	NN
cord-010027-r0tl01kq	1648	6	in	in	IN
cord-010027-r0tl01kq	1648	7	which	which	WDT
cord-010027-r0tl01kq	1648	8	an	an	DT
cord-010027-r0tl01kq	1648	9	unexpected	unexpected	JJ
cord-010027-r0tl01kq	1648	10	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1648	11	of	of	IN
cord-010027-r0tl01kq	1648	12	KFD	KFD	NNP
cord-010027-r0tl01kq	1648	13	was	be	VBD
cord-010027-r0tl01kq	1648	14	made	make	VBN
cord-010027-r0tl01kq	1648	15	via	via	IN
cord-010027-r0tl01kq	1648	16	transbronchial	transbronchial	JJ
cord-010027-r0tl01kq	1648	17	biopsy	biopsy	NN
cord-010027-r0tl01kq	1648	18	of	of	IN
cord-010027-r0tl01kq	1648	19	mediastinal	mediastinal	JJ
cord-010027-r0tl01kq	1648	20	lymph	lymph	NN
cord-010027-r0tl01kq	1648	21	nodes	node	NNS
cord-010027-r0tl01kq	1648	22	.	.	.
cord-010027-r0tl01kq	1649	1	A	a	DT
cord-010027-r0tl01kq	1649	2	15	15	CD
cord-010027-r0tl01kq	1649	3	year	year	NN
cord-010027-r0tl01kq	1649	4	old	old	JJ
cord-010027-r0tl01kq	1649	5	boy	boy	NN
cord-010027-r0tl01kq	1649	6	of	of	IN
cord-010027-r0tl01kq	1649	7	Pakistani	pakistani	JJ
cord-010027-r0tl01kq	1649	8	origin	origin	NN
cord-010027-r0tl01kq	1649	9	presented	present	VBN
cord-010027-r0tl01kq	1649	10	with	with	IN
cord-010027-r0tl01kq	1649	11	a	a	DT
cord-010027-r0tl01kq	1649	12	4	4	CD
cord-010027-r0tl01kq	1649	13	month	month	NN
cord-010027-r0tl01kq	1649	14	history	history	NN
cord-010027-r0tl01kq	1649	15	of	of	IN
cord-010027-r0tl01kq	1649	16	lethargy	lethargy	NN
cord-010027-r0tl01kq	1649	17	,	,	,
cord-010027-r0tl01kq	1649	18	neck	neck	NN
cord-010027-r0tl01kq	1649	19	stiffness	stiffness	NN
cord-010027-r0tl01kq	1649	20	and	and	CC
cord-010027-r0tl01kq	1649	21	weight	weight	NN
cord-010027-r0tl01kq	1649	22	loss	loss	NN
cord-010027-r0tl01kq	1649	23	,	,	,
cord-010027-r0tl01kq	1649	24	with	with	IN
cord-010027-r0tl01kq	1649	25	fever	fever	NN
cord-010027-r0tl01kq	1649	26	(	(	-LRB-
cord-010027-r0tl01kq	1649	27	up	up	IN
cord-010027-r0tl01kq	1649	28	to	to	TO
cord-010027-r0tl01kq	1649	29	40	40	CD
cord-010027-r0tl01kq	1649	30	°	°	NN
cord-010027-r0tl01kq	1649	31	C	c	NN
cord-010027-r0tl01kq	1649	32	)	)	-RRB-
cord-010027-r0tl01kq	1649	33	and	and	CC
cord-010027-r0tl01kq	1649	34	night	night	NN
cord-010027-r0tl01kq	1649	35	sweats	sweat	NNS
cord-010027-r0tl01kq	1649	36	.	.	.
cord-010027-r0tl01kq	1650	1	Chest	chest	NN
cord-010027-r0tl01kq	1650	2	X	x	NN
cord-010027-r0tl01kq	1650	3	-	-	NN
cord-010027-r0tl01kq	1650	4	ray	ray	NN
cord-010027-r0tl01kq	1650	5	,	,	,
cord-010027-r0tl01kq	1650	6	Mantoux	Mantoux	NNP
cord-010027-r0tl01kq	1650	7	test	test	NN
cord-010027-r0tl01kq	1650	8	,	,	,
cord-010027-r0tl01kq	1650	9	blood	blood	NN
cord-010027-r0tl01kq	1650	10	cultures	culture	NNS
cord-010027-r0tl01kq	1650	11	and	and	CC
cord-010027-r0tl01kq	1650	12	viral	viral	JJ
cord-010027-r0tl01kq	1650	13	PCR	PCR	NNP
cord-010027-r0tl01kq	1650	14	were	be	VBD
cord-010027-r0tl01kq	1650	15	negative	negative	JJ
cord-010027-r0tl01kq	1650	16	.	.	.
cord-010027-r0tl01kq	1651	1	Lumbar	lumbar	JJ
cord-010027-r0tl01kq	1651	2	puncture	puncture	NN
cord-010027-r0tl01kq	1651	3	was	be	VBD
cord-010027-r0tl01kq	1651	4	normal	normal	JJ
cord-010027-r0tl01kq	1651	5	,	,	,
cord-010027-r0tl01kq	1651	6	with	with	IN
cord-010027-r0tl01kq	1651	7	no	no	DT
cord-010027-r0tl01kq	1651	8	acid	acid	NN
cord-010027-r0tl01kq	1651	9	fast	fast	RB
cord-010027-r0tl01kq	1651	10	-	-	HYPH
cord-010027-r0tl01kq	1651	11	bacilli	bacilli	JJ
cord-010027-r0tl01kq	1651	12	.	.	.
cord-010027-r0tl01kq	1652	1	CT	CT	NNP
cord-010027-r0tl01kq	1652	2	showed	show	VBD
cord-010027-r0tl01kq	1652	3	enlargement	enlargement	NN
cord-010027-r0tl01kq	1652	4	of	of	IN
cord-010027-r0tl01kq	1652	5	the	the	DT
cord-010027-r0tl01kq	1652	6	deep	deep	JJ
cord-010027-r0tl01kq	1652	7	cervical	cervical	JJ
cord-010027-r0tl01kq	1652	8	lymph	lymph	NN
cord-010027-r0tl01kq	1652	9	nodes	node	NNS
cord-010027-r0tl01kq	1652	10	(	(	-LRB-
cord-010027-r0tl01kq	1652	11	PETpositive	PETpositive	NNP
cord-010027-r0tl01kq	1652	12	on	on	IN
cord-010027-r0tl01kq	1652	13	further	further	JJ
cord-010027-r0tl01kq	1652	14	imaging	imaging	NN
cord-010027-r0tl01kq	1652	15	)	)	-RRB-
cord-010027-r0tl01kq	1652	16	,	,	,
cord-010027-r0tl01kq	1652	17	and	and	CC
cord-010027-r0tl01kq	1652	18	mediastinal	mediastinal	JJ
cord-010027-r0tl01kq	1652	19	lymphadenopathy	lymphadenopathy	NN
cord-010027-r0tl01kq	1652	20	.	.	.
cord-010027-r0tl01kq	1653	1	He	-PRON-	PRP
cord-010027-r0tl01kq	1653	2	was	be	VBD
cord-010027-r0tl01kq	1653	3	transferred	transfer	VBN
cord-010027-r0tl01kq	1653	4	to	to	IN
cord-010027-r0tl01kq	1653	5	our	-PRON-	PRP$
cord-010027-r0tl01kq	1653	6	hospital	hospital	NN
cord-010027-r0tl01kq	1653	7	for	for	IN
cord-010027-r0tl01kq	1653	8	further	further	JJ
cord-010027-r0tl01kq	1653	9	management	management	NN
cord-010027-r0tl01kq	1653	10	,	,	,
cord-010027-r0tl01kq	1653	11	with	with	IN
cord-010027-r0tl01kq	1653	12	a	a	DT
cord-010027-r0tl01kq	1653	13	differential	differential	JJ
cord-010027-r0tl01kq	1653	14	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1653	15	of	of	IN
cord-010027-r0tl01kq	1653	16	TB	TB	NNP
cord-010027-r0tl01kq	1653	17	,	,	,
cord-010027-r0tl01kq	1653	18	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1653	19	,	,	,
cord-010027-r0tl01kq	1653	20	rare	rare	JJ
cord-010027-r0tl01kq	1653	21	infection	infection	NN
cord-010027-r0tl01kq	1653	22	or	or	CC
cord-010027-r0tl01kq	1653	23	autoimmune	autoimmune	JJ
cord-010027-r0tl01kq	1653	24	disease	disease	NN
cord-010027-r0tl01kq	1653	25	.	.	.
cord-010027-r0tl01kq	1654	1	He	-PRON-	PRP
cord-010027-r0tl01kq	1654	2	underwent	undergo	VBD
cord-010027-r0tl01kq	1654	3	transbronchial	transbronchial	JJ
cord-010027-r0tl01kq	1654	4	biopsy	biopsy	NN
cord-010027-r0tl01kq	1654	5	of	of	IN
cord-010027-r0tl01kq	1654	6	the	the	DT
cord-010027-r0tl01kq	1654	7	mediastinal	mediastinal	JJ
cord-010027-r0tl01kq	1654	8	lymph	lymph	NN
cord-010027-r0tl01kq	1654	9	nodes	node	NNS
cord-010027-r0tl01kq	1654	10	.	.	.
cord-010027-r0tl01kq	1655	1	Results	result	NNS
cord-010027-r0tl01kq	1655	2	:	:	:
cord-010027-r0tl01kq	1656	1	His	-PRON-	PRP$
cord-010027-r0tl01kq	1656	2	biopsy	biopsy	NN
cord-010027-r0tl01kq	1656	3	showed	show	VBD
cord-010027-r0tl01kq	1656	4	blood	blood	NN
cord-010027-r0tl01kq	1656	5	clot	clot	NN
cord-010027-r0tl01kq	1656	6	and	and	CC
cord-010027-r0tl01kq	1656	7	cores	core	NNS
cord-010027-r0tl01kq	1656	8	of	of	IN
cord-010027-r0tl01kq	1656	9	lymph	lymph	NN
cord-010027-r0tl01kq	1656	10	node	node	NN
cord-010027-r0tl01kq	1656	11	,	,	,
cord-010027-r0tl01kq	1656	12	with	with	IN
cord-010027-r0tl01kq	1656	13	focal	focal	JJ
cord-010027-r0tl01kq	1656	14	collections	collection	NNS
cord-010027-r0tl01kq	1656	15	of	of	IN
cord-010027-r0tl01kq	1656	16	crescentic	crescentic	JJ
cord-010027-r0tl01kq	1656	17	macrophages	macrophage	NNS
cord-010027-r0tl01kq	1656	18	,	,	,
cord-010027-r0tl01kq	1656	19	admixed	admix	VBN
cord-010027-r0tl01kq	1656	20	lymphocytes	lymphocyte	NNS
cord-010027-r0tl01kq	1656	21	and	and	CC
cord-010027-r0tl01kq	1656	22	prominent	prominent	JJ
cord-010027-r0tl01kq	1656	23	apoptotic	apoptotic	JJ
cord-010027-r0tl01kq	1656	24	debris	debris	NN
cord-010027-r0tl01kq	1656	25	.	.	.
cord-010027-r0tl01kq	1657	1	Immunohistochemistry	Immunohistochemistry	NNP
cord-010027-r0tl01kq	1657	2	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	1657	3	a	a	DT
cord-010027-r0tl01kq	1657	4	population	population	NN
cord-010027-r0tl01kq	1657	5	of	of	IN
cord-010027-r0tl01kq	1657	6	CD123-positive	cd123-positive	JJ
cord-010027-r0tl01kq	1657	7	plasmacytoid	plasmacytoid	NNP
cord-010027-r0tl01kq	1657	8	dendritic	dendritic	JJ
cord-010027-r0tl01kq	1657	9	cells	cell	NNS
cord-010027-r0tl01kq	1657	10	and	and	CC
cord-010027-r0tl01kq	1657	11	granular	granular	JJ
cord-010027-r0tl01kq	1657	12	MPO	MPO	NNP
cord-010027-r0tl01kq	1657	13	positivity	positivity	NN
cord-010027-r0tl01kq	1657	14	in	in	IN
cord-010027-r0tl01kq	1657	15	macrophage	macrophage	NN
cord-010027-r0tl01kq	1657	16	cytoplasm	cytoplasm	NN
cord-010027-r0tl01kq	1657	17	.	.	.
cord-010027-r0tl01kq	1658	1	The	the	DT
cord-010027-r0tl01kq	1658	2	background	background	NN
cord-010027-r0tl01kq	1658	3	lymphocytes	lymphocyte	NNS
cord-010027-r0tl01kq	1658	4	were	be	VBD
cord-010027-r0tl01kq	1658	5	mainly	mainly	RB
cord-010027-r0tl01kq	1658	6	CD8-positive	CD8-positive	NNP
cord-010027-r0tl01kq	1658	7	T	t	NN
cord-010027-r0tl01kq	1658	8	-	-	HYPH
cord-010027-r0tl01kq	1658	9	cells	cell	NNS
cord-010027-r0tl01kq	1658	10	.	.	.
cord-010027-r0tl01kq	1659	1	The	the	DT
cord-010027-r0tl01kq	1659	2	features	feature	NNS
cord-010027-r0tl01kq	1659	3	were	be	VBD
cord-010027-r0tl01kq	1659	4	those	those	DT
cord-010027-r0tl01kq	1659	5	of	of	IN
cord-010027-r0tl01kq	1659	6	KFD	KFD	NNP
cord-010027-r0tl01kq	1659	7	.	.	.
cord-010027-r0tl01kq	1660	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1660	2	:	:	:
cord-010027-r0tl01kq	1661	1	Involvement	involvement	NN
cord-010027-r0tl01kq	1661	2	of	of	IN
cord-010027-r0tl01kq	1661	3	deep	deep	JJ
cord-010027-r0tl01kq	1661	4	lymph	lymph	NN
cord-010027-r0tl01kq	1661	5	nodes	node	NNS
cord-010027-r0tl01kq	1661	6	is	be	VBZ
cord-010027-r0tl01kq	1661	7	unusual	unusual	JJ
cord-010027-r0tl01kq	1661	8	in	in	IN
cord-010027-r0tl01kq	1661	9	KFD	KFD	NNP
cord-010027-r0tl01kq	1661	10	,	,	,
cord-010027-r0tl01kq	1661	11	and	and	CC
cord-010027-r0tl01kq	1661	12	to	to	IN
cord-010027-r0tl01kq	1661	13	our	-PRON-	PRP$
cord-010027-r0tl01kq	1661	14	knowledge	knowledge	NN
cord-010027-r0tl01kq	1661	15	,	,	,
cord-010027-r0tl01kq	1661	16	this	this	DT
cord-010027-r0tl01kq	1661	17	is	be	VBZ
cord-010027-r0tl01kq	1661	18	the	the	DT
cord-010027-r0tl01kq	1661	19	first	first	JJ
cord-010027-r0tl01kq	1661	20	case	case	NN
cord-010027-r0tl01kq	1661	21	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1661	22	via	via	IN
cord-010027-r0tl01kq	1661	23	transbronchial	transbronchial	JJ
cord-010027-r0tl01kq	1661	24	biopsy	biopsy	NN
cord-010027-r0tl01kq	1661	25	.	.	.
cord-010027-r0tl01kq	1662	1	Such	such	JJ
cord-010027-r0tl01kq	1662	2	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1662	3	often	often	RB
cord-010027-r0tl01kq	1662	4	produce	produce	VBP
cord-010027-r0tl01kq	1662	5	scanty	scanty	JJ
cord-010027-r0tl01kq	1662	6	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1662	7	material	material	NN
cord-010027-r0tl01kq	1662	8	,	,	,
cord-010027-r0tl01kq	1662	9	and	and	CC
cord-010027-r0tl01kq	1662	10	here	here	RB
cord-010027-r0tl01kq	1662	11	the	the	DT
cord-010027-r0tl01kq	1662	12	detection	detection	NN
cord-010027-r0tl01kq	1662	13	of	of	IN
cord-010027-r0tl01kq	1662	14	the	the	DT
cord-010027-r0tl01kq	1662	15	characteristic	characteristic	JJ
cord-010027-r0tl01kq	1662	16	immunoprofile	immunoprofile	NN
cord-010027-r0tl01kq	1662	17	of	of	IN
cord-010027-r0tl01kq	1662	18	KFD	KFD	NNP
cord-010027-r0tl01kq	1662	19	helped	help	VBD
cord-010027-r0tl01kq	1662	20	confirm	confirm	VB
cord-010027-r0tl01kq	1662	21	the	the	DT
cord-010027-r0tl01kq	1662	22	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1662	23	.	.	.
cord-010027-r0tl01kq	1663	1	This	this	DT
cord-010027-r0tl01kq	1663	2	case	case	NN
cord-010027-r0tl01kq	1663	3	highlights	highlight	VBZ
cord-010027-r0tl01kq	1663	4	that	that	IN
cord-010027-r0tl01kq	1663	5	KFD	KFD	NNP
cord-010027-r0tl01kq	1663	6	should	should	MD
cord-010027-r0tl01kq	1663	7	be	be	VB
cord-010027-r0tl01kq	1663	8	considered	consider	VBN
cord-010027-r0tl01kq	1663	9	at	at	IN
cord-010027-r0tl01kq	1663	10	sites	site	NNS
cord-010027-r0tl01kq	1663	11	other	other	JJ
cord-010027-r0tl01kq	1663	12	than	than	IN
cord-010027-r0tl01kq	1663	13	the	the	DT
cord-010027-r0tl01kq	1663	14	cervical	cervical	JJ
cord-010027-r0tl01kq	1663	15	lymph	lymph	NN
cord-010027-r0tl01kq	1663	16	nodes	node	NNS
cord-010027-r0tl01kq	1663	17	,	,	,
cord-010027-r0tl01kq	1663	18	and	and	CC
cord-010027-r0tl01kq	1663	19	demonstrates	demonstrate	VBZ
cord-010027-r0tl01kq	1663	20	the	the	DT
cord-010027-r0tl01kq	1663	21	value	value	NN
cord-010027-r0tl01kq	1663	22	of	of	IN
cord-010027-r0tl01kq	1663	23	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1663	24	in	in	IN
cord-010027-r0tl01kq	1663	25	reaching	reach	VBG
cord-010027-r0tl01kq	1663	26	a	a	DT
cord-010027-r0tl01kq	1663	27	definitive	definitive	JJ
cord-010027-r0tl01kq	1663	28	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1663	29	.	.	.
cord-010027-r0tl01kq	1664	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1664	2	describe	describe	VBP
cord-010027-r0tl01kq	1664	3	a	a	DT
cord-010027-r0tl01kq	1664	4	benign	benign	JJ
cord-010027-r0tl01kq	1664	5	intravascular	intravascular	JJ
cord-010027-r0tl01kq	1664	6	proliferation	proliferation	NN
cord-010027-r0tl01kq	1664	7	of	of	IN
cord-010027-r0tl01kq	1664	8	atypical	atypical	JJ
cord-010027-r0tl01kq	1664	9	polytypic	polytypic	JJ
cord-010027-r0tl01kq	1664	10	CD30	CD30	NNP
cord-010027-r0tl01kq	1664	11	positive	positive	JJ
cord-010027-r0tl01kq	1664	12	T	t	NN
cord-010027-r0tl01kq	1664	13	cells	cell	NNS
cord-010027-r0tl01kq	1664	14	,	,	,
cord-010027-r0tl01kq	1664	15	co	co	VBD
cord-010027-r0tl01kq	1664	16	-	-	JJ
cord-010027-r0tl01kq	1664	17	expressing	express	VBG
cord-010027-r0tl01kq	1664	18	follicular	follicular	JJ
cord-010027-r0tl01kq	1664	19	T	T	NNP
cord-010027-r0tl01kq	1664	20	helper	helper	NN
cord-010027-r0tl01kq	1664	21	cell	cell	NN
cord-010027-r0tl01kq	1664	22	lineage	lineage	NN
cord-010027-r0tl01kq	1664	23	markers	marker	NNS
cord-010027-r0tl01kq	1664	24	coincidental	coincidental	JJ
cord-010027-r0tl01kq	1664	25	to	to	IN
cord-010027-r0tl01kq	1664	26	local	local	JJ
cord-010027-r0tl01kq	1664	27	sepsis	sepsis	NN
cord-010027-r0tl01kq	1664	28	of	of	IN
cord-010027-r0tl01kq	1664	29	the	the	DT
cord-010027-r0tl01kq	1664	30	buttock	buttock	NN
cord-010027-r0tl01kq	1664	31	.	.	.
cord-010027-r0tl01kq	1665	1	A	a	DT
cord-010027-r0tl01kq	1665	2	43	43	CD
cord-010027-r0tl01kq	1665	3	year	year	NN
cord-010027-r0tl01kq	1665	4	old	old	JJ
cord-010027-r0tl01kq	1665	5	female	female	NN
cord-010027-r0tl01kq	1665	6	presented	present	VBN
cord-010027-r0tl01kq	1665	7	with	with	IN
cord-010027-r0tl01kq	1665	8	a	a	DT
cord-010027-r0tl01kq	1665	9	5x5	5x5	CD
cord-010027-r0tl01kq	1665	10	cm	cm	NN
cord-010027-r0tl01kq	1665	11	buttock	buttock	NN
cord-010027-r0tl01kq	1665	12	abscess	abscess	NN
cord-010027-r0tl01kq	1665	13	at	at	IN
cord-010027-r0tl01kq	1665	14	the	the	DT
cord-010027-r0tl01kq	1665	15	site	site	NN
cord-010027-r0tl01kq	1665	16	of	of	IN
cord-010027-r0tl01kq	1665	17	a	a	DT
cord-010027-r0tl01kq	1665	18	longstanding	longstanding	JJ
cord-010027-r0tl01kq	1665	19	palpable	palpable	JJ
cord-010027-r0tl01kq	1665	20	lump	lump	NN
cord-010027-r0tl01kq	1665	21	.	.	.
cord-010027-r0tl01kq	1666	1	Peripheral	peripheral	JJ
cord-010027-r0tl01kq	1666	2	blood	blood	NN
cord-010027-r0tl01kq	1666	3	showed	show	VBD
cord-010027-r0tl01kq	1666	4	only	only	RB
cord-010027-r0tl01kq	1666	5	a	a	DT
cord-010027-r0tl01kq	1666	6	neutrophilic	neutrophilic	JJ
cord-010027-r0tl01kq	1666	7	leucocytosis	leucocytosis	NN
cord-010027-r0tl01kq	1666	8	.	.	.
cord-010027-r0tl01kq	1667	1	Immunohistological	Immunohistological	NNP
cord-010027-r0tl01kq	1667	2	examination	examination	NN
cord-010027-r0tl01kq	1667	3	showed	show	VBD
cord-010027-r0tl01kq	1667	4	large	large	JJ
cord-010027-r0tl01kq	1667	5	aggregates	aggregate	NNS
cord-010027-r0tl01kq	1667	6	of	of	IN
cord-010027-r0tl01kq	1667	7	atypical	atypical	JJ
cord-010027-r0tl01kq	1667	8	CD30	CD30	NNP
cord-010027-r0tl01kq	1667	9	positive	positive	JJ
cord-010027-r0tl01kq	1667	10	,	,	,
cord-010027-r0tl01kq	1667	11	ALK	ALK	NNP
cord-010027-r0tl01kq	1667	12	negative	negative	JJ
cord-010027-r0tl01kq	1667	13	lymphoid	lymphoid	JJ
cord-010027-r0tl01kq	1667	14	cells	cell	NNS
cord-010027-r0tl01kq	1667	15	expressing	express	VBG
cord-010027-r0tl01kq	1667	16	a	a	DT
cord-010027-r0tl01kq	1667	17	pan	pan	NN
cord-010027-r0tl01kq	1667	18	T	T	NNP
cord-010027-r0tl01kq	1667	19	helper	helper	NN
cord-010027-r0tl01kq	1667	20	phenotype	phenotype	NN
cord-010027-r0tl01kq	1667	21	with	with	IN
cord-010027-r0tl01kq	1667	22	CD7	CD7	NNP
cord-010027-r0tl01kq	1667	23	partially	partially	RB
cord-010027-r0tl01kq	1667	24	downregulated	downregulate	VBD
cord-010027-r0tl01kq	1667	25	.	.	.
cord-010027-r0tl01kq	1668	1	Podoplanin	Podoplanin	NNP
cord-010027-r0tl01kq	1668	2	proved	prove	VBD
cord-010027-r0tl01kq	1668	3	that	that	IN
cord-010027-r0tl01kq	1668	4	the	the	DT
cord-010027-r0tl01kq	1668	5	atypical	atypical	JJ
cord-010027-r0tl01kq	1668	6	T	t	NN
cord-010027-r0tl01kq	1668	7	cells	cell	NNS
cord-010027-r0tl01kq	1668	8	were	be	VBD
cord-010027-r0tl01kq	1668	9	primarily	primarily	RB
cord-010027-r0tl01kq	1668	10	,	,	,
cord-010027-r0tl01kq	1668	11	but	but	CC
cord-010027-r0tl01kq	1668	12	not	not	RB
cord-010027-r0tl01kq	1668	13	exclusively	exclusively	RB
cord-010027-r0tl01kq	1668	14	,	,	,
cord-010027-r0tl01kq	1668	15	localised	localise	VBN
cord-010027-r0tl01kq	1668	16	within	within	IN
cord-010027-r0tl01kq	1668	17	lymphatic	lymphatic	JJ
cord-010027-r0tl01kq	1668	18	channels	channel	NNS
cord-010027-r0tl01kq	1668	19	.	.	.
cord-010027-r0tl01kq	1669	1	A	a	DT
cord-010027-r0tl01kq	1669	2	T	t	NN
cord-010027-r0tl01kq	1669	3	cell	cell	NN
cord-010027-r0tl01kq	1669	4	receptor	receptor	NN
cord-010027-r0tl01kq	1669	5	clone	clone	NN
cord-010027-r0tl01kq	1669	6	was	be	VBD
cord-010027-r0tl01kq	1669	7	not	not	RB
cord-010027-r0tl01kq	1669	8	detected	detect	VBN
cord-010027-r0tl01kq	1669	9	using	use	VBG
cord-010027-r0tl01kq	1669	10	PCR	PCR	NNP
cord-010027-r0tl01kq	1669	11	.	.	.
cord-010027-r0tl01kq	1670	1	To	to	TO
cord-010027-r0tl01kq	1670	2	find	find	VB
cord-010027-r0tl01kq	1670	3	intravascular	intravascular	JJ
cord-010027-r0tl01kq	1670	4	concentrations	concentration	NNS
cord-010027-r0tl01kq	1670	5	of	of	IN
cord-010027-r0tl01kq	1670	6	atypical	atypical	JJ
cord-010027-r0tl01kq	1670	7	lymphoid	lymphoid	JJ
cord-010027-r0tl01kq	1670	8	cells	cell	NNS
cord-010027-r0tl01kq	1670	9	is	be	VBZ
cord-010027-r0tl01kq	1670	10	uncommon	uncommon	JJ
cord-010027-r0tl01kq	1670	11	in	in	IN
cord-010027-r0tl01kq	1670	12	skin	skin	NN
cord-010027-r0tl01kq	1670	13	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1670	14	and	and	CC
cord-010027-r0tl01kq	1670	15	raises	raise	VBZ
cord-010027-r0tl01kq	1670	16	the	the	DT
cord-010027-r0tl01kq	1670	17	possibility	possibility	NN
cord-010027-r0tl01kq	1670	18	of	of	IN
cord-010027-r0tl01kq	1670	19	leukaemia	leukaemia	NN
cord-010027-r0tl01kq	1670	20	or	or	CC
cord-010027-r0tl01kq	1670	21	intravascular	intravascular	JJ
cord-010027-r0tl01kq	1670	22	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1670	23	.	.	.
cord-010027-r0tl01kq	1671	1	Intravascular	Intravascular	NNP
cord-010027-r0tl01kq	1671	2	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1671	3	is	be	VBZ
cord-010027-r0tl01kq	1671	4	a	a	DT
cord-010027-r0tl01kq	1671	5	rare	rare	JJ
cord-010027-r0tl01kq	1671	6	variant	variant	NN
cord-010027-r0tl01kq	1671	7	of	of	IN
cord-010027-r0tl01kq	1671	8	non	non	JJ
cord-010027-r0tl01kq	1671	9	Hodgkin	Hodgkin	NNP
cord-010027-r0tl01kq	1671	10	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1671	11	with	with	IN
cord-010027-r0tl01kq	1671	12	a	a	DT
cord-010027-r0tl01kq	1671	13	minority	minority	NN
cord-010027-r0tl01kq	1671	14	possessing	possess	VBG
cord-010027-r0tl01kq	1671	15	T	T	NNP
cord-010027-r0tl01kq	1671	16	or	or	CC
cord-010027-r0tl01kq	1671	17	NK	NK	NNP
cord-010027-r0tl01kq	1671	18	cell	cell	NN
cord-010027-r0tl01kq	1671	19	lineage	lineage	NN
cord-010027-r0tl01kq	1671	20	but	but	CC
cord-010027-r0tl01kq	1671	21	frequently	frequently	RB
cord-010027-r0tl01kq	1671	22	involving	involve	VBG
cord-010027-r0tl01kq	1671	23	skin	skin	NN
cord-010027-r0tl01kq	1671	24	.	.	.
cord-010027-r0tl01kq	1672	1	CD30	CD30	NNP
cord-010027-r0tl01kq	1672	2	is	be	VBZ
cord-010027-r0tl01kq	1672	3	a	a	DT
cord-010027-r0tl01kq	1672	4	transmembrane	transmembrane	NN
cord-010027-r0tl01kq	1672	5	glycoprotein	glycoprotein	NN
cord-010027-r0tl01kq	1672	6	and	and	CC
cord-010027-r0tl01kq	1672	7	a	a	DT
cord-010027-r0tl01kq	1672	8	member	member	NN
cord-010027-r0tl01kq	1672	9	of	of	IN
cord-010027-r0tl01kq	1672	10	the	the	DT
cord-010027-r0tl01kq	1672	11	TNF	TNF	NNP
cord-010027-r0tl01kq	1672	12	superfamily	superfamily	NN
cord-010027-r0tl01kq	1672	13	involved	involve	VBN
cord-010027-r0tl01kq	1672	14	in	in	IN
cord-010027-r0tl01kq	1672	15	regulating	regulate	VBG
cord-010027-r0tl01kq	1672	16	proliferation	proliferation	NN
cord-010027-r0tl01kq	1672	17	.	.	.
cord-010027-r0tl01kq	1673	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1673	2	is	be	VBZ
cord-010027-r0tl01kq	1673	3	considered	consider	VBN
cord-010027-r0tl01kq	1673	4	a	a	DT
cord-010027-r0tl01kq	1673	5	reliable	reliable	JJ
cord-010027-r0tl01kq	1673	6	marker	marker	NN
cord-010027-r0tl01kq	1673	7	of	of	IN
cord-010027-r0tl01kq	1673	8	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1673	9	.	.	.
cord-010027-r0tl01kq	1674	1	Primary	primary	JJ
cord-010027-r0tl01kq	1674	2	cutaneous	cutaneous	JJ
cord-010027-r0tl01kq	1674	3	CD30	CD30	NNP
cord-010027-r0tl01kq	1674	4	positive	positive	JJ
cord-010027-r0tl01kq	1674	5	TLPDs	tlpd	NNS
cord-010027-r0tl01kq	1674	6	encompass	encompass	VBP
cord-010027-r0tl01kq	1674	7	a	a	DT
cord-010027-r0tl01kq	1674	8	spectrum	spectrum	NN
cord-010027-r0tl01kq	1674	9	of	of	IN
cord-010027-r0tl01kq	1674	10	biological	biological	JJ
cord-010027-r0tl01kq	1674	11	aggressiveness	aggressiveness	NN
cord-010027-r0tl01kq	1674	12	and	and	CC
cord-010027-r0tl01kq	1674	13	include	include	VBP
cord-010027-r0tl01kq	1674	14	primary	primary	JJ
cord-010027-r0tl01kq	1674	15	cutaneous	cutaneous	JJ
cord-010027-r0tl01kq	1674	16	anaplastic	anaplastic	JJ
cord-010027-r0tl01kq	1674	17	large	large	JJ
cord-010027-r0tl01kq	1674	18	-	-	HYPH
cord-010027-r0tl01kq	1674	19	cell	cell	NN
cord-010027-r0tl01kq	1674	20	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1674	21	and	and	CC
cord-010027-r0tl01kq	1674	22	lymphomatoid	lymphomatoid	NNP
cord-010027-r0tl01kq	1674	23	papulosis	papulosis	NNP
cord-010027-r0tl01kq	1674	24	(	(	-LRB-
cord-010027-r0tl01kq	1674	25	LyP	lyp	NN
cord-010027-r0tl01kq	1674	26	)	)	-RRB-
cord-010027-r0tl01kq	1674	27	.	.	.
cord-010027-r0tl01kq	1675	1	CD30	CD30	NNP
cord-010027-r0tl01kq	1675	2	can	can	MD
cord-010027-r0tl01kq	1675	3	also	also	RB
cord-010027-r0tl01kq	1675	4	be	be	VB
cord-010027-r0tl01kq	1675	5	up	up	RB
cord-010027-r0tl01kq	1675	6	regulated	regulate	VBN
cord-010027-r0tl01kq	1675	7	in	in	IN
cord-010027-r0tl01kq	1675	8	activated	activate	VBN
cord-010027-r0tl01kq	1675	9	B	B	NNP
cord-010027-r0tl01kq	1675	10	and	and	CC
cord-010027-r0tl01kq	1675	11	T	T	NNP
cord-010027-r0tl01kq	1675	12	cells	cell	NNS
cord-010027-r0tl01kq	1675	13	and	and	CC
cord-010027-r0tl01kq	1675	14	it	-PRON-	PRP
cord-010027-r0tl01kq	1675	15	has	have	VBZ
cord-010027-r0tl01kq	1675	16	been	be	VBN
cord-010027-r0tl01kq	1675	17	proposed	propose	VBN
cord-010027-r0tl01kq	1675	18	that	that	IN
cord-010027-r0tl01kq	1675	19	CD30	CD30	NNP
cord-010027-r0tl01kq	1675	20	positive	positive	JJ
cord-010027-r0tl01kq	1675	21	ivTLPDs	ivtlpd	NNS
cord-010027-r0tl01kq	1675	22	are	be	VBP
cord-010027-r0tl01kq	1675	23	equivalent	equivalent	JJ
cord-010027-r0tl01kq	1675	24	to	to	IN
cord-010027-r0tl01kq	1675	25	an	an	DT
cord-010027-r0tl01kq	1675	26	intravascular	intravascular	JJ
cord-010027-r0tl01kq	1675	27	form	form	NN
cord-010027-r0tl01kq	1675	28	of	of	IN
cord-010027-r0tl01kq	1675	29	LyP.	LyP.	NNP
cord-010027-r0tl01kq	1675	30	Intravascular	Intravascular	NNP
cord-010027-r0tl01kq	1675	31	proliferations	proliferation	NNS
cord-010027-r0tl01kq	1675	32	of	of	IN
cord-010027-r0tl01kq	1675	33	atypical	atypical	JJ
cord-010027-r0tl01kq	1675	34	CD30	CD30	NNP
cord-010027-r0tl01kq	1675	35	positive	positive	JJ
cord-010027-r0tl01kq	1675	36	T	t	NN
cord-010027-r0tl01kq	1675	37	cells	cell	NNS
cord-010027-r0tl01kq	1675	38	have	have	VBP
cord-010027-r0tl01kq	1675	39	been	be	VBN
cord-010027-r0tl01kq	1675	40	linked	link	VBN
cord-010027-r0tl01kq	1675	41	with	with	IN
cord-010027-r0tl01kq	1675	42	chronic	chronic	JJ
cord-010027-r0tl01kq	1675	43	inflammation	inflammation	NN
cord-010027-r0tl01kq	1675	44	and	and	CC
cord-010027-r0tl01kq	1675	45	abscess	abscess	NN
cord-010027-r0tl01kq	1675	46	formation	formation	NN
cord-010027-r0tl01kq	1675	47	.	.	.
cord-010027-r0tl01kq	1676	1	Furthermore	furthermore	RB
cord-010027-r0tl01kq	1676	2	atypical	atypical	JJ
cord-010027-r0tl01kq	1676	3	CD30	CD30	NNP
cord-010027-r0tl01kq	1676	4	positive	positive	JJ
cord-010027-r0tl01kq	1676	5	TLPD	TLPD	NNP
cord-010027-r0tl01kq	1676	6	expressing	express	VBG
cord-010027-r0tl01kq	1676	7	a	a	DT
cord-010027-r0tl01kq	1676	8	CD4	CD4	NNP
cord-010027-r0tl01kq	1676	9	positive	positive	JJ
cord-010027-r0tl01kq	1676	10	T	T	NNP
cord-010027-r0tl01kq	1676	11	helper	helper	NN
cord-010027-r0tl01kq	1676	12	phenotype	phenotype	NN
cord-010027-r0tl01kq	1676	13	and	and	CC
cord-010027-r0tl01kq	1676	14	exhibiting	exhibit	VBG
cord-010027-r0tl01kq	1676	15	an	an	DT
cord-010027-r0tl01kq	1676	16	indolent	indolent	JJ
cord-010027-r0tl01kq	1676	17	clinical	clinical	JJ
cord-010027-r0tl01kq	1676	18	course	course	NN
cord-010027-r0tl01kq	1676	19	have	have	VBP
cord-010027-r0tl01kq	1676	20	been	be	VBN
cord-010027-r0tl01kq	1676	21	reported	report	VBN
cord-010027-r0tl01kq	1676	22	in	in	IN
cord-010027-r0tl01kq	1676	23	the	the	DT
cord-010027-r0tl01kq	1676	24	arm	arm	NN
cord-010027-r0tl01kq	1676	25	,	,	,
cord-010027-r0tl01kq	1676	26	trunk	trunk	NN
cord-010027-r0tl01kq	1676	27	,	,	,
cord-010027-r0tl01kq	1676	28	neck	neck	NN
cord-010027-r0tl01kq	1676	29	and	and	CC
cord-010027-r0tl01kq	1676	30	prepuce	prepuce	NN
cord-010027-r0tl01kq	1676	31	.	.	.
cord-010027-r0tl01kq	1677	1	Ultimately	ultimately	RB
cord-010027-r0tl01kq	1677	2	ivTLPD	ivtlpd	PRP
cord-010027-r0tl01kq	1677	3	may	may	MD
cord-010027-r0tl01kq	1677	4	require	require	VB
cord-010027-r0tl01kq	1677	5	follow	follow	VB
cord-010027-r0tl01kq	1677	6	up	up	RP
cord-010027-r0tl01kq	1677	7	based	base	VBN
cord-010027-r0tl01kq	1677	8	upon	upon	IN
cord-010027-r0tl01kq	1677	9	clinical	clinical	JJ
cord-010027-r0tl01kq	1677	10	features	feature	NNS
cord-010027-r0tl01kq	1677	11	and	and	CC
cord-010027-r0tl01kq	1677	12	natural	natural	JJ
cord-010027-r0tl01kq	1677	13	progression	progression	NN
cord-010027-r0tl01kq	1677	14	due	due	IN
cord-010027-r0tl01kq	1677	15	to	to	IN
cord-010027-r0tl01kq	1677	16	overlapping	overlap	VBG
cord-010027-r0tl01kq	1677	17	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1677	18	features	feature	NNS
cord-010027-r0tl01kq	1677	19	.	.	.
cord-010027-r0tl01kq	1678	1	P	p	NN
cord-010027-r0tl01kq	1678	2	G	G	NNP
cord-010027-r0tl01kq	1678	3	Laing	Laing	NNP
cord-010027-r0tl01kq	1678	4	;	;	:
cord-010027-r0tl01kq	1678	5	S	S	NNP
cord-010027-r0tl01kq	1678	6	Craig	Craig	NNP
cord-010027-r0tl01kq	1678	7	;	;	:
cord-010027-r0tl01kq	1678	8	L	L	NNP
cord-010027-r0tl01kq	1678	9	Moss	Moss	NNP
cord-010027-r0tl01kq	1678	10	;	;	:
cord-010027-r0tl01kq	1678	11	C	C	NNP
cord-010027-r0tl01kq	1678	12	Crichton	Crichton	NNP
cord-010027-r0tl01kq	1678	13	;	;	:
cord-010027-r0tl01kq	1678	14	P	P	NNP
cord-010027-r0tl01kq	1678	15	Johnston	Johnston	NNP
cord-010027-r0tl01kq	1679	1	The	the	DT
cord-010027-r0tl01kq	1679	2	investigation	investigation	NN
cord-010027-r0tl01kq	1679	3	of	of	IN
cord-010027-r0tl01kq	1679	4	lymphoid	lymphoid	JJ
cord-010027-r0tl01kq	1679	5	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	1679	6	requires	require	VBZ
cord-010027-r0tl01kq	1679	7	multiple	multiple	JJ
cord-010027-r0tl01kq	1679	8	sections	section	NNS
cord-010027-r0tl01kq	1679	9	,	,	,
cord-010027-r0tl01kq	1679	10	in	in	IN
cord-010027-r0tl01kq	1679	11	our	-PRON-	PRP$
cord-010027-r0tl01kq	1679	12	practice	practice	NN
cord-010027-r0tl01kq	1679	13	consisting	consist	VBG
cord-010027-r0tl01kq	1679	14	of	of	IN
cord-010027-r0tl01kq	1679	15	twelve	twelve	CD
cord-010027-r0tl01kq	1679	16	antibodies	antibody	NNS
cord-010027-r0tl01kq	1679	17	and	and	CC
cord-010027-r0tl01kq	1679	18	thirteen	thirteen	CD
cord-010027-r0tl01kq	1679	19	single	single	JJ
cord-010027-r0tl01kq	1679	20	stained	stained	JJ
cord-010027-r0tl01kq	1679	21	slides	slide	NNS
cord-010027-r0tl01kq	1679	22	.	.	.
cord-010027-r0tl01kq	1680	1	By	by	IN
cord-010027-r0tl01kq	1680	2	selecting	select	VBG
cord-010027-r0tl01kq	1680	3	particular	particular	JJ
cord-010027-r0tl01kq	1680	4	antibodies	antibody	NNS
cord-010027-r0tl01kq	1680	5	for	for	IN
cord-010027-r0tl01kq	1680	6	double	double	JJ
cord-010027-r0tl01kq	1680	7	staining	staining	NN
cord-010027-r0tl01kq	1680	8	,	,	,
cord-010027-r0tl01kq	1680	9	spatial	spatial	JJ
cord-010027-r0tl01kq	1680	10	relationships	relationship	NNS
cord-010027-r0tl01kq	1680	11	between	between	IN
cord-010027-r0tl01kq	1680	12	cell	cell	NN
cord-010027-r0tl01kq	1680	13	types	type	NNS
cord-010027-r0tl01kq	1680	14	and	and	CC
cord-010027-r0tl01kq	1680	15	overall	overall	JJ
cord-010027-r0tl01kq	1680	16	tissue	tissue	NN
cord-010027-r0tl01kq	1680	17	organisation	organisation	NN
cord-010027-r0tl01kq	1680	18	can	can	MD
cord-010027-r0tl01kq	1680	19	be	be	VB
cord-010027-r0tl01kq	1680	20	more	more	RBR
cord-010027-r0tl01kq	1680	21	easily	easily	RB
cord-010027-r0tl01kq	1680	22	visualised	visualise	VBN
cord-010027-r0tl01kq	1680	23	.	.	.
cord-010027-r0tl01kq	1681	1	This	this	DT
cord-010027-r0tl01kq	1681	2	pilot	pilot	NN
cord-010027-r0tl01kq	1681	3	study	study	NN
cord-010027-r0tl01kq	1681	4	aimed	aim	VBN
cord-010027-r0tl01kq	1681	5	to	to	TO
cord-010027-r0tl01kq	1681	6	optimise	optimise	VB
cord-010027-r0tl01kq	1681	7	the	the	DT
cord-010027-r0tl01kq	1681	8	staining	stain	VBG
cord-010027-r0tl01kq	1681	9	intensity	intensity	NN
cord-010027-r0tl01kq	1681	10	and	and	CC
cord-010027-r0tl01kq	1681	11	specificity	specificity	NN
cord-010027-r0tl01kq	1681	12	to	to	TO
cord-010027-r0tl01kq	1681	13	provide	provide	VB
cord-010027-r0tl01kq	1681	14	accurate	accurate	JJ
cord-010027-r0tl01kq	1681	15	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1681	16	information	information	NN
cord-010027-r0tl01kq	1681	17	,	,	,
cord-010027-r0tl01kq	1681	18	reduce	reduce	VB
cord-010027-r0tl01kq	1681	19	slide	slide	NN
cord-010027-r0tl01kq	1681	20	number	number	NN
cord-010027-r0tl01kq	1681	21	,	,	,
cord-010027-r0tl01kq	1681	22	material	material	NN
cord-010027-r0tl01kq	1681	23	and	and	CC
cord-010027-r0tl01kq	1681	24	consumables	consumable	NNS
cord-010027-r0tl01kq	1681	25	costs	cost	NNS
cord-010027-r0tl01kq	1681	26	,	,	,
cord-010027-r0tl01kq	1681	27	preparation	preparation	NN
cord-010027-r0tl01kq	1681	28	time	time	NN
cord-010027-r0tl01kq	1681	29	in	in	IN
cord-010027-r0tl01kq	1681	30	the	the	DT
cord-010027-r0tl01kq	1681	31	laboratory	laboratory	NN
cord-010027-r0tl01kq	1681	32	and	and	CC
cord-010027-r0tl01kq	1681	33	storage	storage	NN
cord-010027-r0tl01kq	1681	34	space	space	NN
cord-010027-r0tl01kq	1681	35	to	to	TO
cord-010027-r0tl01kq	1681	36	enhance	enhance	VB
cord-010027-r0tl01kq	1681	37	costbenefit	costbenefit	NNP
cord-010027-r0tl01kq	1681	38	.	.	.
cord-010027-r0tl01kq	1682	1	Twelve	twelve	CD
cord-010027-r0tl01kq	1682	2	antibodies	antibody	NNS
cord-010027-r0tl01kq	1682	3	were	be	VBD
cord-010027-r0tl01kq	1682	4	chosen	choose	VBN
cord-010027-r0tl01kq	1682	5	and	and	CC
cord-010027-r0tl01kq	1682	6	paired	pair	VBN
cord-010027-r0tl01kq	1682	7	:	:	:
cord-010027-r0tl01kq	1682	8	kappa	kappa	NNP
cord-010027-r0tl01kq	1682	9	/	/	SYM
cord-010027-r0tl01kq	1682	10	lambda	lambda	NNP
cord-010027-r0tl01kq	1682	11	,	,	,
cord-010027-r0tl01kq	1682	12	CD3	CD3	NNP
cord-010027-r0tl01kq	1682	13	/	/	SYM
cord-010027-r0tl01kq	1682	14	CD20	CD20	NNP
cord-010027-r0tl01kq	1682	15	,	,	,
cord-010027-r0tl01kq	1682	16	MUM-1	MUM-1	NNP
cord-010027-r0tl01kq	1682	17	/	/	SYM
cord-010027-r0tl01kq	1682	18	CD10	CD10	NNP
cord-010027-r0tl01kq	1682	19	,	,	,
cord-010027-r0tl01kq	1682	20	Cyclin	Cyclin	NNP
cord-010027-r0tl01kq	1682	21	D1	D1	NNP
cord-010027-r0tl01kq	1682	22	/	/	SYM
cord-010027-r0tl01kq	1682	23	CD30	CD30	NNP
cord-010027-r0tl01kq	1682	24	,	,	,
cord-010027-r0tl01kq	1682	25	BCL-6	BCL-6	NNP
cord-010027-r0tl01kq	1682	26	/	/	SYM
cord-010027-r0tl01kq	1682	27	CD5	CD5	NNP
cord-010027-r0tl01kq	1682	28	and	and	CC
cord-010027-r0tl01kq	1682	29	CD5	CD5	NNP
cord-010027-r0tl01kq	1682	30	/	/	SYM
cord-010027-r0tl01kq	1682	31	PAX-5	PAX-5	NNP
cord-010027-r0tl01kq	1682	32	.	.	.
cord-010027-r0tl01kq	1683	1	Firstly	firstly	RB
cord-010027-r0tl01kq	1683	2	,	,	,
cord-010027-r0tl01kq	1683	3	these	these	DT
cord-010027-r0tl01kq	1683	4	combinations	combination	NNS
cord-010027-r0tl01kq	1683	5	were	be	VBD
cord-010027-r0tl01kq	1683	6	applied	apply	VBN
cord-010027-r0tl01kq	1683	7	to	to	IN
cord-010027-r0tl01kq	1683	8	normal	normal	JJ
cord-010027-r0tl01kq	1683	9	tissue	tissue	NN
cord-010027-r0tl01kq	1683	10	and	and	CC
cord-010027-r0tl01kq	1683	11	then	then	RB
cord-010027-r0tl01kq	1683	12	known	know	VBN
cord-010027-r0tl01kq	1683	13	tumours	tumour	NNS
cord-010027-r0tl01kq	1683	14	to	to	TO
cord-010027-r0tl01kq	1683	15	optimise	optimise	VB
cord-010027-r0tl01kq	1683	16	technique	technique	NN
cord-010027-r0tl01kq	1683	17	.	.	.
cord-010027-r0tl01kq	1684	1	Once	once	IN
cord-010027-r0tl01kq	1684	2	the	the	DT
cord-010027-r0tl01kq	1684	3	staining	staining	NN
cord-010027-r0tl01kq	1684	4	protocols	protocol	NNS
cord-010027-r0tl01kq	1684	5	were	be	VBD
cord-010027-r0tl01kq	1684	6	finalised	finalise	VBN
cord-010027-r0tl01kq	1684	7	they	-PRON-	PRP
cord-010027-r0tl01kq	1684	8	were	be	VBD
cord-010027-r0tl01kq	1684	9	run	run	VBN
cord-010027-r0tl01kq	1684	10	on	on	IN
cord-010027-r0tl01kq	1684	11	eleven	eleven	CD
cord-010027-r0tl01kq	1684	12	consecutive	consecutive	JJ
cord-010027-r0tl01kq	1684	13	cases	case	NNS
cord-010027-r0tl01kq	1684	14	with	with	IN
cord-010027-r0tl01kq	1684	15	conventionally	conventionally	RB
cord-010027-r0tl01kq	1684	16	stained	stain	VBN
cord-010027-r0tl01kq	1684	17	Non	Non	NNP
cord-010027-r0tl01kq	1684	18	-	-	JJ
cord-010027-r0tl01kq	1684	19	Hodgkin	Hodgkin	NNP
cord-010027-r0tl01kq	1684	20	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1684	21	(	(	-LRB-
cord-010027-r0tl01kq	1684	22	NHL	NHL	NNP
cord-010027-r0tl01kq	1684	23	)	)	-RRB-
cord-010027-r0tl01kq	1684	24	panel	panel	NN
cord-010027-r0tl01kq	1684	25	requests	request	NNS
cord-010027-r0tl01kq	1684	26	.	.	.
cord-010027-r0tl01kq	1685	1	The	the	DT
cord-010027-r0tl01kq	1685	2	slides	slide	NNS
cord-010027-r0tl01kq	1685	3	were	be	VBD
cord-010027-r0tl01kq	1685	4	then	then	RB
cord-010027-r0tl01kq	1685	5	reviewed	review	VBN
cord-010027-r0tl01kq	1685	6	by	by	IN
cord-010027-r0tl01kq	1685	7	the	the	DT
cord-010027-r0tl01kq	1685	8	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1685	9	team	team	NN
cord-010027-r0tl01kq	1685	10	for	for	IN
cord-010027-r0tl01kq	1685	11	quality	quality	NN
cord-010027-r0tl01kq	1685	12	and	and	CC
cord-010027-r0tl01kq	1685	13	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1685	14	accuracy	accuracy	NN
cord-010027-r0tl01kq	1685	15	compared	compare	VBN
cord-010027-r0tl01kq	1685	16	to	to	IN
cord-010027-r0tl01kq	1685	17	the	the	DT
cord-010027-r0tl01kq	1685	18	standard	standard	JJ
cord-010027-r0tl01kq	1685	19	single	single	JJ
cord-010027-r0tl01kq	1685	20	stained	stained	JJ
cord-010027-r0tl01kq	1685	21	slides	slide	NNS
cord-010027-r0tl01kq	1685	22	.	.	.
cord-010027-r0tl01kq	1686	1	The	the	DT
cord-010027-r0tl01kq	1686	2	results	result	NNS
cord-010027-r0tl01kq	1686	3	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	1686	4	that	that	IN
cord-010027-r0tl01kq	1686	5	double	double	JJ
cord-010027-r0tl01kq	1686	6	staining	staining	NN
cord-010027-r0tl01kq	1686	7	is	be	VBZ
cord-010027-r0tl01kq	1686	8	possible	possible	JJ
cord-010027-r0tl01kq	1686	9	in	in	IN
cord-010027-r0tl01kq	1686	10	the	the	DT
cord-010027-r0tl01kq	1686	11	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1686	12	of	of	IN
cord-010027-r0tl01kq	1686	13	NHL	NHL	NNP
cord-010027-r0tl01kq	1686	14	.	.	.
cord-010027-r0tl01kq	1687	1	The	the	DT
cord-010027-r0tl01kq	1687	2	combinations	combination	NNS
cord-010027-r0tl01kq	1687	3	chosen	choose	VBN
cord-010027-r0tl01kq	1687	4	have	have	VBP
cord-010027-r0tl01kq	1687	5	proved	prove	VBN
cord-010027-r0tl01kq	1687	6	successful	successful	JJ
cord-010027-r0tl01kq	1687	7	and	and	CC
cord-010027-r0tl01kq	1687	8	have	have	VBP
cord-010027-r0tl01kq	1687	9	provided	provide	VBN
cord-010027-r0tl01kq	1687	10	interpretable	interpretable	JJ
cord-010027-r0tl01kq	1687	11	results	result	NNS
cord-010027-r0tl01kq	1687	12	;	;	:
cord-010027-r0tl01kq	1687	13	for	for	IN
cord-010027-r0tl01kq	1687	14	example	example	NN
cord-010027-r0tl01kq	1687	15	,	,	,
cord-010027-r0tl01kq	1687	16	the	the	DT
cord-010027-r0tl01kq	1687	17	relationship	relationship	NN
cord-010027-r0tl01kq	1687	18	of	of	IN
cord-010027-r0tl01kq	1687	19	light	light	JJ
cord-010027-r0tl01kq	1687	20	chain	chain	NN
cord-010027-r0tl01kq	1687	21	staining	stain	VBG
cord-010027-r0tl01kq	1687	22	in	in	IN
cord-010027-r0tl01kq	1687	23	plasma	plasma	NN
cord-010027-r0tl01kq	1687	24	cells	cell	NNS
cord-010027-r0tl01kq	1687	25	,	,	,
cord-010027-r0tl01kq	1687	26	MUM-1	MUM-1	NNP
cord-010027-r0tl01kq	1687	27	and	and	CC
cord-010027-r0tl01kq	1687	28	CD10	CD10	NNP
cord-010027-r0tl01kq	1687	29	positive	positive	JJ
cord-010027-r0tl01kq	1687	30	cells	cell	NNS
cord-010027-r0tl01kq	1687	31	in	in	IN
cord-010027-r0tl01kq	1687	32	Diffuse	diffuse	JJ
cord-010027-r0tl01kq	1687	33	Large	large	JJ
cord-010027-r0tl01kq	1687	34	B	b	NN
cord-010027-r0tl01kq	1687	35	-	-	HYPH
cord-010027-r0tl01kq	1687	36	cell	cell	NN
cord-010027-r0tl01kq	1687	37	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1687	38	proves	prove	VBZ
cord-010027-r0tl01kq	1687	39	positive	positive	JJ
cord-010027-r0tl01kq	1687	40	.	.	.
cord-010027-r0tl01kq	1688	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1688	2	feel	feel	VBP
cord-010027-r0tl01kq	1688	3	time	time	NN
cord-010027-r0tl01kq	1688	4	will	will	MD
cord-010027-r0tl01kq	1688	5	be	be	VB
cord-010027-r0tl01kq	1688	6	saved	save	VBN
cord-010027-r0tl01kq	1688	7	cutting	cut	VBG
cord-010027-r0tl01kq	1688	8	sections	section	NNS
cord-010027-r0tl01kq	1688	9	to	to	TO
cord-010027-r0tl01kq	1688	10	improve	improve	VB
cord-010027-r0tl01kq	1688	11	efficiency	efficiency	NN
cord-010027-r0tl01kq	1688	12	in	in	IN
cord-010027-r0tl01kq	1688	13	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1688	14	investigation	investigation	NN
cord-010027-r0tl01kq	1688	15	and	and	CC
cord-010027-r0tl01kq	1688	16	reduce	reduce	VB
cord-010027-r0tl01kq	1688	17	panel	panel	NN
cord-010027-r0tl01kq	1688	18	storage	storage	NN
cord-010027-r0tl01kq	1688	19	space	space	NN
cord-010027-r0tl01kq	1688	20	by	by	IN
cord-010027-r0tl01kq	1688	21	around	around	IN
cord-010027-r0tl01kq	1688	22	30	30	CD
cord-010027-r0tl01kq	1688	23	%	%	NN
cord-010027-r0tl01kq	1688	24	.	.	.
cord-010027-r0tl01kq	1689	1	In	in	IN
cord-010027-r0tl01kq	1689	2	conclusion	conclusion	NN
cord-010027-r0tl01kq	1689	3	the	the	DT
cord-010027-r0tl01kq	1689	4	outcomes	outcome	NNS
cord-010027-r0tl01kq	1689	5	from	from	IN
cord-010027-r0tl01kq	1689	6	this	this	DT
cord-010027-r0tl01kq	1689	7	pilot	pilot	NN
cord-010027-r0tl01kq	1689	8	study	study	NN
cord-010027-r0tl01kq	1689	9	have	have	VBP
cord-010027-r0tl01kq	1689	10	been	be	VBN
cord-010027-r0tl01kq	1689	11	positive	positive	JJ
cord-010027-r0tl01kq	1689	12	for	for	IN
cord-010027-r0tl01kq	1689	13	medical	medical	JJ
cord-010027-r0tl01kq	1689	14	and	and	CC
cord-010027-r0tl01kq	1689	15	scientific	scientific	JJ
cord-010027-r0tl01kq	1689	16	staff	staff	NN
cord-010027-r0tl01kq	1689	17	,	,	,
cord-010027-r0tl01kq	1689	18	has	have	VBZ
cord-010027-r0tl01kq	1689	19	shown	show	VBN
cord-010027-r0tl01kq	1689	20	that	that	IN
cord-010027-r0tl01kq	1689	21	double	double	JJ
cord-010027-r0tl01kq	1689	22	staining	staining	NN
cord-010027-r0tl01kq	1689	23	in	in	IN
cord-010027-r0tl01kq	1689	24	the	the	DT
cord-010027-r0tl01kq	1689	25	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1689	26	of	of	IN
cord-010027-r0tl01kq	1689	27	NHL	NHL	NNP
cord-010027-r0tl01kq	1689	28	is	be	VBZ
cord-010027-r0tl01kq	1689	29	possible	possible	JJ
cord-010027-r0tl01kq	1689	30	and	and	CC
cord-010027-r0tl01kq	1689	31	that	that	IN
cord-010027-r0tl01kq	1689	32	optimising	optimise	VBG
cord-010027-r0tl01kq	1689	33	this	this	DT
cord-010027-r0tl01kq	1689	34	protocol	protocol	NN
cord-010027-r0tl01kq	1689	35	with	with	IN
cord-010027-r0tl01kq	1689	36	a	a	DT
cord-010027-r0tl01kq	1689	37	view	view	NN
cord-010027-r0tl01kq	1689	38	to	to	TO
cord-010027-r0tl01kq	1689	39	live	live	VB
cord-010027-r0tl01kq	1689	40	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1689	41	is	be	VBZ
cord-010027-r0tl01kq	1689	42	worthwhile	worthwhile	JJ
cord-010027-r0tl01kq	1689	43	.	.	.
cord-010027-r0tl01kq	1690	1	In	in	IN
cord-010027-r0tl01kq	1690	2	an	an	DT
cord-010027-r0tl01kq	1690	3	Age	Age	NNP
cord-010027-r0tl01kq	1690	4	in	in	IN
cord-010027-r0tl01kq	1690	5	which	which	WDT
cord-010027-r0tl01kq	1690	6	Novel	novel	JJ
cord-010027-r0tl01kq	1690	7	therapies	therapy	NNS
cord-010027-r0tl01kq	1690	8	are	be	VBP
cord-010027-r0tl01kq	1690	9	not	not	RB
cord-010027-r0tl01kq	1690	10	necessarily	necessarily	RB
cord-010027-r0tl01kq	1690	11	defined	define	VBN
cord-010027-r0tl01kq	1690	12	by	by	IN
cord-010027-r0tl01kq	1690	13	their	-PRON-	PRP$
cord-010027-r0tl01kq	1690	14	ability	ability	NN
cord-010027-r0tl01kq	1690	15	to	to	TO
cord-010027-r0tl01kq	1690	16	kill	kill	VB
cord-010027-r0tl01kq	1690	17	malignant	malignant	JJ
cord-010027-r0tl01kq	1690	18	cells	cell	NNS
cord-010027-r0tl01kq	1690	19	,	,	,
cord-010027-r0tl01kq	1690	20	understanding	understand	VBG
cord-010027-r0tl01kq	1690	21	the	the	DT
cord-010027-r0tl01kq	1690	22	biology	biology	NN
cord-010027-r0tl01kq	1690	23	of	of	IN
cord-010027-r0tl01kq	1690	24	malignant	malignant	JJ
cord-010027-r0tl01kq	1690	25	cells	cell	NNS
cord-010027-r0tl01kq	1690	26	after	after	IN
cord-010027-r0tl01kq	1690	27	treatment	treatment	NN
cord-010027-r0tl01kq	1690	28	is	be	VBZ
cord-010027-r0tl01kq	1690	29	extremely	extremely	RB
cord-010027-r0tl01kq	1690	30	important	important	JJ
cord-010027-r0tl01kq	1690	31	.	.	.
cord-010027-r0tl01kq	1691	1	This	this	DT
cord-010027-r0tl01kq	1691	2	is	be	VBZ
cord-010027-r0tl01kq	1691	3	particularly	particularly	RB
cord-010027-r0tl01kq	1691	4	true	true	JJ
cord-010027-r0tl01kq	1691	5	of	of	IN
cord-010027-r0tl01kq	1691	6	Ibrutinib	Ibrutinib	NNP
cord-010027-r0tl01kq	1691	7	(	(	-LRB-
cord-010027-r0tl01kq	1691	8	Pcl-32765	Pcl-32765	NNP
cord-010027-r0tl01kq	1691	9	)	)	-RRB-
cord-010027-r0tl01kq	1691	10	therapy	therapy	NN
cord-010027-r0tl01kq	1691	11	in	in	IN
cord-010027-r0tl01kq	1691	12	chronic	chronic	JJ
cord-010027-r0tl01kq	1691	13	lymphocytic	lymphocytic	JJ
cord-010027-r0tl01kq	1691	14	leukaemia	leukaemia	NN
cord-010027-r0tl01kq	1691	15	which	which	WDT
cord-010027-r0tl01kq	1691	16	is	be	VBZ
cord-010027-r0tl01kq	1691	17	characterised	characterise	VBN
cord-010027-r0tl01kq	1691	18	by	by	IN
cord-010027-r0tl01kq	1691	19	lymphocytosis	lymphocytosis	NNP
cord-010027-r0tl01kq	1691	20	.	.	.
cord-010027-r0tl01kq	1692	1	Imagej	Imagej	NNP
cord-010027-r0tl01kq	1692	2	/	/	SYM
cord-010027-r0tl01kq	1692	3	Fiji	Fiji	NNP
cord-010027-r0tl01kq	1692	4	image	image	NN
cord-010027-r0tl01kq	1692	5	analysis	analysis	NN
cord-010027-r0tl01kq	1692	6	software	software	NN
cord-010027-r0tl01kq	1692	7	could	could	MD
cord-010027-r0tl01kq	1692	8	therefore	therefore	RB
cord-010027-r0tl01kq	1692	9	be	be	VB
cord-010027-r0tl01kq	1692	10	used	use	VBN
cord-010027-r0tl01kq	1692	11	to	to	TO
cord-010027-r0tl01kq	1692	12	analyse	analyse	VB
cord-010027-r0tl01kq	1692	13	cell	cell	NN
cord-010027-r0tl01kq	1692	14	shape	shape	NN
cord-010027-r0tl01kq	1692	15	and	and	CC
cord-010027-r0tl01kq	1692	16	grouping	grouping	NN
cord-010027-r0tl01kq	1692	17	characteristics	characteristic	NNS
cord-010027-r0tl01kq	1692	18	.	.	.
cord-010027-r0tl01kq	1693	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1693	2	used	use	VBD
cord-010027-r0tl01kq	1693	3	a	a	DT
cord-010027-r0tl01kq	1693	4	novel	novel	JJ
cord-010027-r0tl01kq	1693	5	assay	assay	NN
cord-010027-r0tl01kq	1693	6	in	in	IN
cord-010027-r0tl01kq	1693	7	which	which	WDT
cord-010027-r0tl01kq	1693	8	Chronic	Chronic	NNP
cord-010027-r0tl01kq	1693	9	Lymphocytic	lymphocytic	JJ
cord-010027-r0tl01kq	1693	10	Leukaemia	Leukaemia	NNP
cord-010027-r0tl01kq	1693	11	cells	cell	NNS
cord-010027-r0tl01kq	1693	12	,	,	,
cord-010027-r0tl01kq	1693	13	cultured	culture	VBN
cord-010027-r0tl01kq	1693	14	for	for	IN
cord-010027-r0tl01kq	1693	15	5	5	CD
cord-010027-r0tl01kq	1693	16	days	day	NNS
cord-010027-r0tl01kq	1693	17	,	,	,
cord-010027-r0tl01kq	1693	18	were	be	VBD
cord-010027-r0tl01kq	1693	19	seeded	seed	VBN
cord-010027-r0tl01kq	1693	20	onto	onto	IN
cord-010027-r0tl01kq	1693	21	fibronectin	fibronectin	NN
cord-010027-r0tl01kq	1693	22	coated	coat	VBN
cord-010027-r0tl01kq	1693	23	glass	glass	NN
cord-010027-r0tl01kq	1693	24	coverslips	coverslip	NNS
cord-010027-r0tl01kq	1693	25	and	and	CC
cord-010027-r0tl01kq	1693	26	then	then	RB
cord-010027-r0tl01kq	1693	27	had	have	VBD
cord-010027-r0tl01kq	1693	28	their	-PRON-	PRP$
cord-010027-r0tl01kq	1693	29	B	b	NN
cord-010027-r0tl01kq	1693	30	cell	cell	NN
cord-010027-r0tl01kq	1693	31	receptors	receptor	NNS
cord-010027-r0tl01kq	1693	32	ligated	ligate	VBN
cord-010027-r0tl01kq	1693	33	with	with	IN
cord-010027-r0tl01kq	1693	34	goat	goat	NN
cord-010027-r0tl01kq	1693	35	anti	anti	NNP
cord-010027-r0tl01kq	1693	36	human	human	JJ
cord-010027-r0tl01kq	1693	37	Igm	Igm	NNP
cord-010027-r0tl01kq	1693	38	.	.	.
cord-010027-r0tl01kq	1694	1	They	-PRON-	PRP
cord-010027-r0tl01kq	1694	2	were	be	VBD
cord-010027-r0tl01kq	1694	3	compared	compare	VBN
cord-010027-r0tl01kq	1694	4	with	with	IN
cord-010027-r0tl01kq	1694	5	cells	cell	NNS
cord-010027-r0tl01kq	1694	6	simultaneously	simultaneously	RB
cord-010027-r0tl01kq	1694	7	inhibited	inhibit	VBN
cord-010027-r0tl01kq	1694	8	with	with	IN
cord-010027-r0tl01kq	1694	9	Ibrutinib	Ibrutinib	NNP
cord-010027-r0tl01kq	1694	10	.	.	.
cord-010027-r0tl01kq	1695	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1695	2	tested	test	VBD
cord-010027-r0tl01kq	1695	3	multiple	multiple	JJ
cord-010027-r0tl01kq	1695	4	staining	staining	NN
cord-010027-r0tl01kq	1695	5	techniques	technique	NNS
cord-010027-r0tl01kq	1695	6	and	and	CC
cord-010027-r0tl01kq	1695	7	found	find	VBD
cord-010027-r0tl01kq	1695	8	that	that	IN
cord-010027-r0tl01kq	1695	9	using	use	VBG
cord-010027-r0tl01kq	1695	10	either	either	CC
cord-010027-r0tl01kq	1695	11	Rose	Rose	NNP
cord-010027-r0tl01kq	1695	12	Bengal	Bengal	NNP
cord-010027-r0tl01kq	1695	13	or	or	CC
cord-010027-r0tl01kq	1695	14	Texas	Texas	NNP
cord-010027-r0tl01kq	1695	15	Red	Red	NNP
cord-010027-r0tl01kq	1695	16	Phalloidin	Phalloidin	NNP
cord-010027-r0tl01kq	1695	17	staining	staining	NN
cord-010027-r0tl01kq	1695	18	produced	produce	VBD
cord-010027-r0tl01kq	1695	19	the	the	DT
cord-010027-r0tl01kq	1695	20	most	most	RBS
cord-010027-r0tl01kq	1695	21	reproducibly	reproducibly	RB
cord-010027-r0tl01kq	1695	22	analysable	analysable	JJ
cord-010027-r0tl01kq	1695	23	data	datum	NNS
cord-010027-r0tl01kq	1695	24	when	when	WRB
cord-010027-r0tl01kq	1695	25	using	use	VBG
cord-010027-r0tl01kq	1695	26	Imagej/	Imagej/	NNP
cord-010027-r0tl01kq	1695	27	Fiji	Fiji	NNP
cord-010027-r0tl01kq	1695	28	.	.	.
cord-010027-r0tl01kq	1696	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1696	2	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	1696	3	,	,	,
cord-010027-r0tl01kq	1696	4	using	use	VBG
cord-010027-r0tl01kq	1696	5	the	the	DT
cord-010027-r0tl01kq	1696	6	assumption	assumption	NN
cord-010027-r0tl01kq	1696	7	that	that	IN
cord-010027-r0tl01kq	1696	8	the	the	DT
cord-010027-r0tl01kq	1696	9	outline	outline	NN
cord-010027-r0tl01kq	1696	10	of	of	IN
cord-010027-r0tl01kq	1696	11	interacting	interact	VBG
cord-010027-r0tl01kq	1696	12	cells	cell	NNS
cord-010027-r0tl01kq	1696	13	would	would	MD
cord-010027-r0tl01kq	1696	14	be	be	VB
cord-010027-r0tl01kq	1696	15	larger	large	JJR
cord-010027-r0tl01kq	1696	16	than	than	IN
cord-010027-r0tl01kq	1696	17	cells	cell	NNS
cord-010027-r0tl01kq	1696	18	which	which	WDT
cord-010027-r0tl01kq	1696	19	were	be	VBD
cord-010027-r0tl01kq	1696	20	alone	alone	JJ
cord-010027-r0tl01kq	1696	21	that	that	IN
cord-010027-r0tl01kq	1696	22	Homotypic	Homotypic	NNP
cord-010027-r0tl01kq	1696	23	interactions	interaction	NNS
cord-010027-r0tl01kq	1696	24	were	be	VBD
cord-010027-r0tl01kq	1696	25	increased	increase	VBN
cord-010027-r0tl01kq	1696	26	after	after	IN
cord-010027-r0tl01kq	1696	27	B	B	NNP
cord-010027-r0tl01kq	1696	28	Cell	Cell	NNP
cord-010027-r0tl01kq	1696	29	receptor	receptor	NN
cord-010027-r0tl01kq	1696	30	cross	cross	NN
cord-010027-r0tl01kq	1696	31	linking	link	VBG
cord-010027-r0tl01kq	1696	32	(	(	-LRB-
cord-010027-r0tl01kq	1696	33	54	54	CD
cord-010027-r0tl01kq	1696	34	groups	group	NNS
cord-010027-r0tl01kq	1696	35	larger	large	JJR
cord-010027-r0tl01kq	1696	36	than	than	IN
cord-010027-r0tl01kq	1696	37	2	2	CD
cord-010027-r0tl01kq	1696	38	cells	cell	NNS
cord-010027-r0tl01kq	1696	39	against	against	IN
cord-010027-r0tl01kq	1696	40	35	35	CD
cord-010027-r0tl01kq	1696	41	group	group	NN
cord-010027-r0tl01kq	1696	42	larger	large	JJR
cord-010027-r0tl01kq	1696	43	than	than	IN
cord-010027-r0tl01kq	1696	44	2	2	CD
cord-010027-r0tl01kq	1696	45	cells	cell	NNS
cord-010027-r0tl01kq	1696	46	per	per	IN
cord-010027-r0tl01kq	1696	47	500	500	CD
cord-010027-r0tl01kq	1696	48	nm	nm	NN
cord-010027-r0tl01kq	1696	49	X	x	NN
cord-010027-r0tl01kq	1696	50	250	250	CD
cord-010027-r0tl01kq	1696	51	nm	nm	NNP
cord-010027-r0tl01kq	1696	52	Field	Field	NNP
cord-010027-r0tl01kq	1696	53	(	(	-LRB-
cord-010027-r0tl01kq	1696	54	P=0.019	P=0.019	NNP
cord-010027-r0tl01kq	1696	55	)	)	-RRB-
cord-010027-r0tl01kq	1696	56	)	)	-RRB-
cord-010027-r0tl01kq	1696	57	.	.	.
cord-010027-r0tl01kq	1697	1	Nuclei	nucleus	NNS
cord-010027-r0tl01kq	1697	2	were	be	VBD
cord-010027-r0tl01kq	1697	3	also	also	RB
cord-010027-r0tl01kq	1697	4	significantly	significantly	RB
cord-010027-r0tl01kq	1697	5	larger	large	JJR
cord-010027-r0tl01kq	1697	6	when	when	WRB
cord-010027-r0tl01kq	1697	7	cross	cross	NN
cord-010027-r0tl01kq	1697	8	linked	link	VBN
cord-010027-r0tl01kq	1697	9	.	.	.
cord-010027-r0tl01kq	1698	1	(	(	-LRB-
cord-010027-r0tl01kq	1698	2	Mean	mean	JJ
cord-010027-r0tl01kq	1698	3	33.23	33.23	CD
cord-010027-r0tl01kq	1698	4	(	(	-LRB-
cord-010027-r0tl01kq	1698	5	+	+	CC
cord-010027-r0tl01kq	1698	6	-0.43	-0.43	CD
cord-010027-r0tl01kq	1698	7	)	)	-RRB-
cord-010027-r0tl01kq	1698	8	pixels	pixel	NNS
cord-010027-r0tl01kq	1698	9	without	without	IN
cord-010027-r0tl01kq	1698	10	cross	cross	NN
cord-010027-r0tl01kq	1698	11	linking	linking	NN
cord-010027-r0tl01kq	1698	12	and	and	CC
cord-010027-r0tl01kq	1698	13	44.15(+-0.57	44.15(+-0.57	NNP
cord-010027-r0tl01kq	1698	14	)	)	-RRB-
cord-010027-r0tl01kq	1699	1	(	(	-LRB-
cord-010027-r0tl01kq	1699	2	P=≤0.0001	p=≤0.0001	NN
cord-010027-r0tl01kq	1699	3	)	)	-RRB-
cord-010027-r0tl01kq	1699	4	)	)	-RRB-
cord-010027-r0tl01kq	1699	5	suggesting	suggest	VBG
cord-010027-r0tl01kq	1699	6	increased	increase	VBN
cord-010027-r0tl01kq	1699	7	nuclear	nuclear	JJ
cord-010027-r0tl01kq	1699	8	spreading	spreading	NN
cord-010027-r0tl01kq	1699	9	.	.	.
cord-010027-r0tl01kq	1700	1	These	these	DT
cord-010027-r0tl01kq	1700	2	effects	effect	NNS
cord-010027-r0tl01kq	1700	3	were	be	VBD
cord-010027-r0tl01kq	1700	4	reversed	reverse	VBN
cord-010027-r0tl01kq	1700	5	by	by	IN
cord-010027-r0tl01kq	1700	6	the	the	DT
cord-010027-r0tl01kq	1700	7	addition	addition	NN
cord-010027-r0tl01kq	1700	8	Of	of	IN
cord-010027-r0tl01kq	1700	9	Ibrutinib	Ibrutinib	NNP
cord-010027-r0tl01kq	1700	10	with	with	IN
cord-010027-r0tl01kq	1700	11	18	18	CD
cord-010027-r0tl01kq	1700	12	groups	group	NNS
cord-010027-r0tl01kq	1700	13	larger	large	JJR
cord-010027-r0tl01kq	1700	14	than	than	IN
cord-010027-r0tl01kq	1700	15	2	2	CD
cord-010027-r0tl01kq	1700	16	cells	cell	NNS
cord-010027-r0tl01kq	1700	17	per	per	IN
cord-010027-r0tl01kq	1700	18	the	the	DT
cord-010027-r0tl01kq	1700	19	same	same	JJ
cord-010027-r0tl01kq	1700	20	field(P=0.0252	field(p=0.0252	NN
cord-010027-r0tl01kq	1700	21	compared	compare	VBN
cord-010027-r0tl01kq	1700	22	with	with	IN
cord-010027-r0tl01kq	1700	23	cross	cross	NN
cord-010027-r0tl01kq	1700	24	linked	link	VBN
cord-010027-r0tl01kq	1700	25	sells	sell	NNS
cord-010027-r0tl01kq	1700	26	)	)	-RRB-
cord-010027-r0tl01kq	1700	27	and	and	CC
cord-010027-r0tl01kq	1700	28	Nuclear	nuclear	JJ
cord-010027-r0tl01kq	1700	29	size	size	NN
cord-010027-r0tl01kq	1700	30	mean	mean	VBP
cord-010027-r0tl01kq	1700	31	being	be	VBG
cord-010027-r0tl01kq	1700	32	33.83	33.83	CD
cord-010027-r0tl01kq	1701	1	(	(	-LRB-
cord-010027-r0tl01kq	1701	2	P≤0.0001	P≤0.0001	NNP
cord-010027-r0tl01kq	1701	3	compared	compare	VBN
cord-010027-r0tl01kq	1701	4	with	with	IN
cord-010027-r0tl01kq	1701	5	cross	cross	NN
cord-010027-r0tl01kq	1701	6	linked	link	VBN
cord-010027-r0tl01kq	1701	7	cells	cell	NNS
cord-010027-r0tl01kq	1701	8	)	)	-RRB-
cord-010027-r0tl01kq	1701	9	.	.	.
cord-010027-r0tl01kq	1702	1	This	this	DT
cord-010027-r0tl01kq	1702	2	study	study	NN
cord-010027-r0tl01kq	1702	3	demonstrates	demonstrate	VBZ
cord-010027-r0tl01kq	1702	4	a	a	DT
cord-010027-r0tl01kq	1702	5	novel	novel	NN
cord-010027-r0tl01kq	1702	6	,	,	,
cord-010027-r0tl01kq	1702	7	easily	easily	RB
cord-010027-r0tl01kq	1702	8	reproducible	reproducible	JJ
cord-010027-r0tl01kq	1702	9	assay	assay	NN
cord-010027-r0tl01kq	1702	10	to	to	TO
cord-010027-r0tl01kq	1702	11	assess	assess	VB
cord-010027-r0tl01kq	1702	12	a	a	DT
cord-010027-r0tl01kq	1702	13	variety	variety	NN
cord-010027-r0tl01kq	1702	14	of	of	IN
cord-010027-r0tl01kq	1702	15	cellular	cellular	JJ
cord-010027-r0tl01kq	1702	16	responses	response	NNS
cord-010027-r0tl01kq	1702	17	to	to	IN
cord-010027-r0tl01kq	1702	18	Ibrutinib	Ibrutinib	NNP
cord-010027-r0tl01kq	1702	19	therapy	therapy	NN
cord-010027-r0tl01kq	1702	20	and	and	CC
cord-010027-r0tl01kq	1702	21	suggests	suggest	VBZ
cord-010027-r0tl01kq	1702	22	a	a	DT
cord-010027-r0tl01kq	1702	23	method	method	NN
cord-010027-r0tl01kq	1702	24	of	of	IN
cord-010027-r0tl01kq	1702	25	quantifying	quantify	VBG
cord-010027-r0tl01kq	1702	26	activity	activity	NN
cord-010027-r0tl01kq	1702	27	both	both	CC
cord-010027-r0tl01kq	1702	28	when	when	WRB
cord-010027-r0tl01kq	1702	29	stimulated	stimulate	VBN
cord-010027-r0tl01kq	1702	30	and	and	CC
cord-010027-r0tl01kq	1702	31	inhibited	inhibit	VBN
cord-010027-r0tl01kq	1702	32	.	.	.
cord-010027-r0tl01kq	1703	1	This	this	DT
cord-010027-r0tl01kq	1703	2	technique	technique	NN
cord-010027-r0tl01kq	1703	3	could	could	MD
cord-010027-r0tl01kq	1703	4	easily	easily	RB
cord-010027-r0tl01kq	1703	5	be	be	VB
cord-010027-r0tl01kq	1703	6	scaled	scale	VBN
cord-010027-r0tl01kq	1703	7	up	up	RP
cord-010027-r0tl01kq	1703	8	to	to	TO
cord-010027-r0tl01kq	1703	9	further	further	RB
cord-010027-r0tl01kq	1703	10	investigate	investigate	VB
cord-010027-r0tl01kq	1703	11	cellular	cellular	JJ
cord-010027-r0tl01kq	1703	12	behaviour	behaviour	NN
cord-010027-r0tl01kq	1703	13	following	follow	VBG
cord-010027-r0tl01kq	1703	14	Ibrutinib	Ibrutinib	NNP
cord-010027-r0tl01kq	1703	15	therapy	therapy	NN
cord-010027-r0tl01kq	1703	16	.	.	.
cord-010027-r0tl01kq	1704	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1704	2	:	:	:
cord-010027-r0tl01kq	1704	3	Gliomas	Gliomas	NNP
cord-010027-r0tl01kq	1704	4	represent	represent	VBP
cord-010027-r0tl01kq	1704	5	43	43	CD
cord-010027-r0tl01kq	1704	6	%	%	NN
cord-010027-r0tl01kq	1704	7	of	of	IN
cord-010027-r0tl01kq	1704	8	all	all	DT
cord-010027-r0tl01kq	1704	9	solid	solid	JJ
cord-010027-r0tl01kq	1704	10	intracranial	intracranial	JJ
cord-010027-r0tl01kq	1704	11	tumours	tumour	NNS
cord-010027-r0tl01kq	1704	12	and	and	CC
cord-010027-r0tl01kq	1704	13	are	be	VBP
cord-010027-r0tl01kq	1704	14	associated	associate	VBN
cord-010027-r0tl01kq	1704	15	with	with	IN
cord-010027-r0tl01kq	1704	16	a	a	DT
cord-010027-r0tl01kq	1704	17	poor	poor	JJ
cord-010027-r0tl01kq	1704	18	prognosis	prognosis	NN
cord-010027-r0tl01kq	1704	19	.	.	.
cord-010027-r0tl01kq	1705	1	Recent	recent	JJ
cord-010027-r0tl01kq	1705	2	studies	study	NNS
cord-010027-r0tl01kq	1705	3	indicated	indicate	VBD
cord-010027-r0tl01kq	1705	4	that	that	IN
cord-010027-r0tl01kq	1705	5	the	the	DT
cord-010027-r0tl01kq	1705	6	human	human	JJ
cord-010027-r0tl01kq	1705	7	cytosolic	cytosolic	JJ
cord-010027-r0tl01kq	1705	8	branched	branched	JJ
cord-010027-r0tl01kq	1705	9	chain	chain	NN
cord-010027-r0tl01kq	1705	10	aminotransferase	aminotransferase	NN
cord-010027-r0tl01kq	1705	11	protein	protein	NN
cord-010027-r0tl01kq	1705	12	(	(	-LRB-
cord-010027-r0tl01kq	1705	13	hBCATc	hBCATc	NNP
cord-010027-r0tl01kq	1705	14	)	)	-RRB-
cord-010027-r0tl01kq	1705	15	,	,	,
cord-010027-r0tl01kq	1705	16	which	which	WDT
cord-010027-r0tl01kq	1705	17	metabolises	metabolise	VBZ
cord-010027-r0tl01kq	1705	18	the	the	DT
cord-010027-r0tl01kq	1705	19	branched	branched	JJ
cord-010027-r0tl01kq	1705	20	chain	chain	NN
cord-010027-r0tl01kq	1705	21	amino	amino	NN
cord-010027-r0tl01kq	1705	22	acids	acid	NNS
cord-010027-r0tl01kq	1705	23	(	(	-LRB-
cord-010027-r0tl01kq	1705	24	BCAA	BCAA	NNP
cord-010027-r0tl01kq	1705	25	)	)	-RRB-
cord-010027-r0tl01kq	1705	26	,	,	,
cord-010027-r0tl01kq	1705	27	was	be	VBD
cord-010027-r0tl01kq	1705	28	significantly	significantly	RB
cord-010027-r0tl01kq	1705	29	upregulated	upregulate	VBN
cord-010027-r0tl01kq	1705	30	in	in	IN
cord-010027-r0tl01kq	1705	31	IDH1/2	IDH1/2	``
cord-010027-r0tl01kq	1705	32	wild	wild	JJ
cord-010027-r0tl01kq	1705	33	type	type	NN
cord-010027-r0tl01kq	1705	34	(	(	-LRB-
cord-010027-r0tl01kq	1705	35	WT	WT	NNP
cord-010027-r0tl01kq	1705	36	)	)	-RRB-
cord-010027-r0tl01kq	1705	37	glioblastomas	glioblastomas	NNP
cord-010027-r0tl01kq	1705	38	,	,	,
cord-010027-r0tl01kq	1705	39	correlated	correlate	VBN
cord-010027-r0tl01kq	1705	40	with	with	IN
cord-010027-r0tl01kq	1705	41	methylation	methylation	NN
cord-010027-r0tl01kq	1705	42	patterns	pattern	NNS
cord-010027-r0tl01kq	1705	43	in	in	IN
cord-010027-r0tl01kq	1705	44	the	the	DT
cord-010027-r0tl01kq	1705	45	BCAT1	BCAT1	NNP
cord-010027-r0tl01kq	1705	46	promoter	promoter	NN
cord-010027-r0tl01kq	1705	47	and	and	CC
cord-010027-r0tl01kq	1705	48	is	be	VBZ
cord-010027-r0tl01kq	1705	49	associated	associate	VBN
cord-010027-r0tl01kq	1705	50	with	with	IN
cord-010027-r0tl01kq	1705	51	a	a	DT
cord-010027-r0tl01kq	1705	52	worse	bad	JJR
cord-010027-r0tl01kq	1705	53	prognosis	prognosis	NN
cord-010027-r0tl01kq	1705	54	compared	compare	VBN
cord-010027-r0tl01kq	1705	55	with	with	IN
cord-010027-r0tl01kq	1705	56	IDH	IDH	NNP
cord-010027-r0tl01kq	1705	57	mutant	mutant	JJ
cord-010027-r0tl01kq	1705	58	gliomas	glioma	NNS
cord-010027-r0tl01kq	1705	59	.	.	.
cord-010027-r0tl01kq	1706	1	The	the	DT
cord-010027-r0tl01kq	1706	2	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1706	3	and	and	CC
cord-010027-r0tl01kq	1706	4	prognostic	prognostic	JJ
cord-010027-r0tl01kq	1706	5	significance	significance	NN
cord-010027-r0tl01kq	1706	6	of	of	IN
cord-010027-r0tl01kq	1706	7	markers	marker	NNS
cord-010027-r0tl01kq	1706	8	of	of	IN
cord-010027-r0tl01kq	1706	9	BCAA	BCAA	NNP
cord-010027-r0tl01kq	1706	10	metabolism	metabolism	NN
cord-010027-r0tl01kq	1706	11	is	be	VBZ
cord-010027-r0tl01kq	1706	12	currently	currently	RB
cord-010027-r0tl01kq	1706	13	under	under	IN
cord-010027-r0tl01kq	1706	14	investigation	investigation	NN
cord-010027-r0tl01kq	1706	15	.	.	.
cord-010027-r0tl01kq	1707	1	Methods	method	NNS
cord-010027-r0tl01kq	1707	2	:	:	:
cord-010027-r0tl01kq	1707	3	64	64	CD
cord-010027-r0tl01kq	1707	4	glioma	glioma	NN
cord-010027-r0tl01kq	1707	5	tumour	tumour	NN
cord-010027-r0tl01kq	1707	6	samples	sample	NNS
cord-010027-r0tl01kq	1707	7	were	be	VBD
cord-010027-r0tl01kq	1707	8	compared	compare	VBN
cord-010027-r0tl01kq	1707	9	for	for	IN
cord-010027-r0tl01kq	1707	10	hBCATc	hbcatc	CD
cord-010027-r0tl01kq	1707	11	,	,	,
cord-010027-r0tl01kq	1707	12	hBCATm	hbcatm	NN
cord-010027-r0tl01kq	1707	13	and	and	CC
cord-010027-r0tl01kq	1707	14	BCKDC	BCKDC	NNP
cord-010027-r0tl01kq	1707	15	expression	expression	NN
cord-010027-r0tl01kq	1707	16	using	use	VBG
cord-010027-r0tl01kq	1707	17	western	western	JJ
cord-010027-r0tl01kq	1707	18	blotting	blotting	NN
cord-010027-r0tl01kq	1707	19	and	and	CC
cord-010027-r0tl01kq	1707	20	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1707	21	.	.	.
cord-010027-r0tl01kq	1708	1	DNA	DNA	NNP
cord-010027-r0tl01kq	1708	2	was	be	VBD
cord-010027-r0tl01kq	1708	3	extracted	extract	VBN
cord-010027-r0tl01kq	1708	4	from	from	IN
cord-010027-r0tl01kq	1708	5	fresh	fresh	JJ
cord-010027-r0tl01kq	1708	6	frozen	frozen	JJ
cord-010027-r0tl01kq	1708	7	tissue	tissue	NN
cord-010027-r0tl01kq	1708	8	.	.	.
cord-010027-r0tl01kq	1709	1	Sanger	Sanger	NNP
cord-010027-r0tl01kq	1709	2	sequencing	sequencing	NN
cord-010027-r0tl01kq	1709	3	of	of	IN
cord-010027-r0tl01kq	1709	4	the	the	DT
cord-010027-r0tl01kq	1709	5	p.	p.	NN
cord-010027-r0tl01kq	1710	1	Arg132	Arg132	NFP
cord-010027-r0tl01kq	1710	2	region	region	NN
cord-010027-r0tl01kq	1710	3	of	of	IN
cord-010027-r0tl01kq	1710	4	IDH1	IDH1	NNP
cord-010027-r0tl01kq	1710	5	and	and	CC
cord-010027-r0tl01kq	1710	6	p.	p.	NN
cord-010027-r0tl01kq	1711	1	Arg172	arg172	DT
cord-010027-r0tl01kq	1711	2	region	region	NN
cord-010027-r0tl01kq	1711	3	of	of	IN
cord-010027-r0tl01kq	1711	4	IDH2	IDH2	NNP
cord-010027-r0tl01kq	1711	5	was	be	VBD
cord-010027-r0tl01kq	1711	6	undertaken	undertake	VBN
cord-010027-r0tl01kq	1711	7	using	use	VBG
cord-010027-r0tl01kq	1711	8	a	a	DT
cord-010027-r0tl01kq	1711	9	3730	3730	CD
cord-010027-r0tl01kq	1711	10	DNA	dna	NN
cord-010027-r0tl01kq	1711	11	analyser	analyser	NN
cord-010027-r0tl01kq	1711	12	(	(	-LRB-
cord-010027-r0tl01kq	1711	13	Applied	Applied	NNP
cord-010027-r0tl01kq	1711	14	Bio	Bio	NNP
cord-010027-r0tl01kq	1711	15	-	-	HYPH
cord-010027-r0tl01kq	1711	16	Systems	Systems	NNP
cord-010027-r0tl01kq	1711	17	)	)	-RRB-
cord-010027-r0tl01kq	1711	18	.	.	.
cord-010027-r0tl01kq	1712	1	SUMMARY	summary	NN
cord-010027-r0tl01kq	1712	2	:	:	:
cord-010027-r0tl01kq	1713	1	In	in	IN
cord-010027-r0tl01kq	1713	2	IDH	IDH	NNP
cord-010027-r0tl01kq	1713	3	WT	WT	NNP
cord-010027-r0tl01kq	1713	4	tumours	tumour	NNS
cord-010027-r0tl01kq	1713	5	,	,	,
cord-010027-r0tl01kq	1713	6	like	like	IN
cord-010027-r0tl01kq	1713	7	hBCATc	hbcatc	CD
cord-010027-r0tl01kq	1713	8	(	(	-LRB-
cord-010027-r0tl01kq	1713	9	p=0.007	p=0.007	NNP
cord-010027-r0tl01kq	1713	10	)	)	-RRB-
cord-010027-r0tl01kq	1713	11	,	,	,
cord-010027-r0tl01kq	1713	12	the	the	DT
cord-010027-r0tl01kq	1713	13	expression	expression	NN
cord-010027-r0tl01kq	1713	14	of	of	IN
cord-010027-r0tl01kq	1713	15	the	the	DT
cord-010027-r0tl01kq	1713	16	mitochondrial	mitochondrial	JJ
cord-010027-r0tl01kq	1713	17	isoform	isoform	NN
cord-010027-r0tl01kq	1713	18	(	(	-LRB-
cord-010027-r0tl01kq	1713	19	hBCATm	hbcatm	NN
cord-010027-r0tl01kq	1713	20	)	)	-RRB-
cord-010027-r0tl01kq	1713	21	is	be	VBZ
cord-010027-r0tl01kq	1713	22	significantly	significantly	RB
cord-010027-r0tl01kq	1713	23	(	(	-LRB-
cord-010027-r0tl01kq	1713	24	p=0.036	p=0.036	JJ
cord-010027-r0tl01kq	1713	25	)	)	-RRB-
cord-010027-r0tl01kq	1713	26	expressed	express	VBD
cord-010027-r0tl01kq	1713	27	relative	relative	NN
cord-010027-r0tl01kq	1713	28	to	to	IN
cord-010027-r0tl01kq	1713	29	IDH	IDH	NNP
cord-010027-r0tl01kq	1713	30	mutant	mutant	JJ
cord-010027-r0tl01kq	1713	31	gliomas	glioma	NNS
cord-010027-r0tl01kq	1713	32	.	.	.
cord-010027-r0tl01kq	1714	1	hBCATm	hbcatm	RB
cord-010027-r0tl01kq	1714	2	additionally	additionally	RB
cord-010027-r0tl01kq	1714	3	shows	show	VBZ
cord-010027-r0tl01kq	1714	4	a	a	DT
cord-010027-r0tl01kq	1714	5	more	more	RBR
cord-010027-r0tl01kq	1714	6	significant	significant	JJ
cord-010027-r0tl01kq	1714	7	correlation	correlation	NN
cord-010027-r0tl01kq	1714	8	with	with	IN
cord-010027-r0tl01kq	1714	9	patient	patient	JJ
cord-010027-r0tl01kq	1714	10	survival	survival	NN
cord-010027-r0tl01kq	1714	11	than	than	IN
cord-010027-r0tl01kq	1714	12	hBCATc	hbcatc	CD
cord-010027-r0tl01kq	1714	13	on	on	IN
cord-010027-r0tl01kq	1714	14	Kaplan	Kaplan	NNP
cord-010027-r0tl01kq	1714	15	-	-	HYPH
cord-010027-r0tl01kq	1714	16	Meier	Meier	NNP
cord-010027-r0tl01kq	1714	17	analysis	analysis	NN
cord-010027-r0tl01kq	1714	18	.	.	.
cord-010027-r0tl01kq	1715	1	In	in	IN
cord-010027-r0tl01kq	1715	2	IDH	IDH	NNP
cord-010027-r0tl01kq	1715	3	WT	WT	NNP
cord-010027-r0tl01kq	1715	4	tumours	tumour	NNS
cord-010027-r0tl01kq	1715	5	,	,	,
cord-010027-r0tl01kq	1715	6	low	low	JJ
cord-010027-r0tl01kq	1715	7	hBCATm	hbcatm	DT
cord-010027-r0tl01kq	1715	8	expression	expression	NN
cord-010027-r0tl01kq	1715	9	is	be	VBZ
cord-010027-r0tl01kq	1715	10	a	a	DT
cord-010027-r0tl01kq	1715	11	positive	positive	JJ
cord-010027-r0tl01kq	1715	12	prognostic	prognostic	JJ
cord-010027-r0tl01kq	1715	13	factor	factor	NN
cord-010027-r0tl01kq	1715	14	(	(	-LRB-
cord-010027-r0tl01kq	1715	15	p	p	NN
cord-010027-r0tl01kq	1715	16	=	=	SYM
cord-010027-r0tl01kq	1715	17	0.003	0.003	CD
cord-010027-r0tl01kq	1715	18	)	)	-RRB-
cord-010027-r0tl01kq	1715	19	.	.	.
cord-010027-r0tl01kq	1716	1	hBCATm	hbcatm	DT
cord-010027-r0tl01kq	1716	2	expression	expression	NN
cord-010027-r0tl01kq	1716	3	additionally	additionally	RB
cord-010027-r0tl01kq	1716	4	correlated	correlate	VBD
cord-010027-r0tl01kq	1716	5	with	with	IN
cord-010027-r0tl01kq	1716	6	WHO	WHO	NNP
cord-010027-r0tl01kq	1716	7	grade	grade	NN
cord-010027-r0tl01kq	1716	8	.	.	.
cord-010027-r0tl01kq	1717	1	Although	although	IN
cord-010027-r0tl01kq	1717	2	previous	previous	JJ
cord-010027-r0tl01kq	1717	3	reports	report	NNS
cord-010027-r0tl01kq	1717	4	indicate	indicate	VBP
cord-010027-r0tl01kq	1717	5	that	that	IN
cord-010027-r0tl01kq	1717	6	increased	increase	VBN
cord-010027-r0tl01kq	1717	7	hBCATc	hbcatc	NN
cord-010027-r0tl01kq	1717	8	occurs	occur	VBZ
cord-010027-r0tl01kq	1717	9	exclusively	exclusively	RB
cord-010027-r0tl01kq	1717	10	in	in	IN
cord-010027-r0tl01kq	1717	11	IDH	IDH	NNP
cord-010027-r0tl01kq	1717	12	-	-	HYPH
cord-010027-r0tl01kq	1717	13	WT	WT	NNP
cord-010027-r0tl01kq	1717	14	tumours	tumour	NNS
cord-010027-r0tl01kq	1717	15	,	,	,
cord-010027-r0tl01kq	1717	16	our	-PRON-	PRP$
cord-010027-r0tl01kq	1717	17	studies	study	NNS
cord-010027-r0tl01kq	1717	18	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	1717	19	that	that	IN
cord-010027-r0tl01kq	1717	20	30	30	CD
cord-010027-r0tl01kq	1717	21	%	%	NN
cord-010027-r0tl01kq	1717	22	of	of	IN
cord-010027-r0tl01kq	1717	23	IDH	IDH	NNP
cord-010027-r0tl01kq	1717	24	mutant	mutant	JJ
cord-010027-r0tl01kq	1717	25	tumours	tumour	NNS
cord-010027-r0tl01kq	1717	26	express	express	VBP
cord-010027-r0tl01kq	1717	27	comparable	comparable	JJ
cord-010027-r0tl01kq	1717	28	levels	level	NNS
cord-010027-r0tl01kq	1717	29	of	of	IN
cord-010027-r0tl01kq	1717	30	hBCATc	hbcatc	CD
cord-010027-r0tl01kq	1717	31	.	.	.
cord-010027-r0tl01kq	1718	1	Although	although	IN
cord-010027-r0tl01kq	1718	2	hBCATc	hbcatc	CD
cord-010027-r0tl01kq	1718	3	alone	alone	RB
cord-010027-r0tl01kq	1718	4	has	have	VBZ
cord-010027-r0tl01kq	1718	5	been	be	VBN
cord-010027-r0tl01kq	1718	6	suggested	suggest	VBN
cord-010027-r0tl01kq	1718	7	as	as	IN
cord-010027-r0tl01kq	1718	8	a	a	DT
cord-010027-r0tl01kq	1718	9	putative	putative	JJ
cord-010027-r0tl01kq	1718	10	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	1718	11	target	target	NN
cord-010027-r0tl01kq	1718	12	,	,	,
cord-010027-r0tl01kq	1718	13	it	-PRON-	PRP
cord-010027-r0tl01kq	1718	14	is	be	VBZ
cord-010027-r0tl01kq	1718	15	important	important	JJ
cord-010027-r0tl01kq	1718	16	to	to	TO
cord-010027-r0tl01kq	1718	17	evaluate	evaluate	VB
cord-010027-r0tl01kq	1718	18	the	the	DT
cord-010027-r0tl01kq	1718	19	expression	expression	NN
cord-010027-r0tl01kq	1718	20	of	of	IN
cord-010027-r0tl01kq	1718	21	hBCATm	hbcatm	DT
cord-010027-r0tl01kq	1718	22	in	in	IN
cord-010027-r0tl01kq	1718	23	glioblastomas	glioblastomas	NNP
cord-010027-r0tl01kq	1718	24	as	as	IN
cord-010027-r0tl01kq	1718	25	its	-PRON-	PRP$
cord-010027-r0tl01kq	1718	26	expression	expression	NN
cord-010027-r0tl01kq	1718	27	may	may	MD
cord-010027-r0tl01kq	1718	28	impact	impact	VB
cord-010027-r0tl01kq	1718	29	the	the	DT
cord-010027-r0tl01kq	1718	30	efficacy	efficacy	NN
cord-010027-r0tl01kq	1718	31	of	of	IN
cord-010027-r0tl01kq	1718	32	new	new	JJ
cord-010027-r0tl01kq	1718	33	treatments	treatment	NNS
cord-010027-r0tl01kq	1718	34	targeting	target	VBG
cord-010027-r0tl01kq	1718	35	hBCATc	hbcatc	CD
cord-010027-r0tl01kq	1718	36	.	.	.
cord-010027-r0tl01kq	1719	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1719	2	:	:	:
cord-010027-r0tl01kq	1720	1	IDH	IDH	NNP
cord-010027-r0tl01kq	1720	2	WT	WT	NNP
cord-010027-r0tl01kq	1720	3	high	high	JJ
cord-010027-r0tl01kq	1720	4	grade	grade	NN
cord-010027-r0tl01kq	1720	5	gliomas	glioma	NNS
cord-010027-r0tl01kq	1720	6	traditionally	traditionally	RB
cord-010027-r0tl01kq	1720	7	have	have	VBP
cord-010027-r0tl01kq	1720	8	a	a	DT
cord-010027-r0tl01kq	1720	9	poor	poor	JJ
cord-010027-r0tl01kq	1720	10	prognosis	prognosis	NN
cord-010027-r0tl01kq	1720	11	.	.	.
cord-010027-r0tl01kq	1721	1	However	however	RB
cord-010027-r0tl01kq	1721	2	we	-PRON-	PRP
cord-010027-r0tl01kq	1721	3	demonstrate	demonstrate	VBP
cord-010027-r0tl01kq	1721	4	for	for	IN
cord-010027-r0tl01kq	1721	5	the	the	DT
cord-010027-r0tl01kq	1721	6	first	first	JJ
cord-010027-r0tl01kq	1721	7	time	time	NN
cord-010027-r0tl01kq	1721	8	that	that	WDT
cord-010027-r0tl01kq	1721	9	relatively	relatively	RB
cord-010027-r0tl01kq	1721	10	low	low	JJ
cord-010027-r0tl01kq	1721	11	hBCATm	hbcatm	PRP
cord-010027-r0tl01kq	1721	12	may	may	MD
cord-010027-r0tl01kq	1721	13	select	select	VB
cord-010027-r0tl01kq	1721	14	for	for	IN
cord-010027-r0tl01kq	1721	15	a	a	DT
cord-010027-r0tl01kq	1721	16	better	well	RBR
cord-010027-r0tl01kq	1721	17	performing	perform	VBG
cord-010027-r0tl01kq	1721	18	clinical	clinical	JJ
cord-010027-r0tl01kq	1721	19	cohort	cohort	NN
cord-010027-r0tl01kq	1721	20	and	and	CC
cord-010027-r0tl01kq	1721	21	may	may	MD
cord-010027-r0tl01kq	1721	22	be	be	VB
cord-010027-r0tl01kq	1721	23	a	a	DT
cord-010027-r0tl01kq	1721	24	possible	possible	JJ
cord-010027-r0tl01kq	1721	25	candidate	candidate	NN
cord-010027-r0tl01kq	1721	26	target	target	NN
cord-010027-r0tl01kq	1721	27	for	for	IN
cord-010027-r0tl01kq	1721	28	drug	drug	NN
cord-010027-r0tl01kq	1721	29	therapy	therapy	NN
cord-010027-r0tl01kq	1721	30	.	.	.
cord-010027-r0tl01kq	1722	1	A	a	DT
cord-010027-r0tl01kq	1722	2	38	38	CD
cord-010027-r0tl01kq	1722	3	year	year	NN
cord-010027-r0tl01kq	1722	4	old	old	JJ
cord-010027-r0tl01kq	1722	5	female	female	NN
cord-010027-r0tl01kq	1722	6	presented	present	VBN
cord-010027-r0tl01kq	1722	7	with	with	IN
cord-010027-r0tl01kq	1722	8	an	an	DT
cord-010027-r0tl01kq	1722	9	occipital	occipital	JJ
cord-010027-r0tl01kq	1722	10	mass	mass	NN
cord-010027-r0tl01kq	1722	11	,	,	,
cord-010027-r0tl01kq	1722	12	presumed	presume	VBN
cord-010027-r0tl01kq	1722	13	to	to	TO
cord-010027-r0tl01kq	1722	14	be	be	VB
cord-010027-r0tl01kq	1722	15	a	a	DT
cord-010027-r0tl01kq	1722	16	lymph	lymph	NN
cord-010027-r0tl01kq	1722	17	node	node	NN
cord-010027-r0tl01kq	1722	18	and	and	CC
cord-010027-r0tl01kq	1722	19	underwent	undergo	VBD
cord-010027-r0tl01kq	1722	20	fine	fine	JJ
cord-010027-r0tl01kq	1722	21	needle	needle	NN
cord-010027-r0tl01kq	1722	22	aspiration	aspiration	NN
cord-010027-r0tl01kq	1722	23	of	of	IN
cord-010027-r0tl01kq	1722	24	the	the	DT
cord-010027-r0tl01kq	1722	25	lesion	lesion	NN
cord-010027-r0tl01kq	1722	26	.	.	.
cord-010027-r0tl01kq	1723	1	FNA	FNA	NNP
cord-010027-r0tl01kq	1723	2	yielded	yield	VBD
cord-010027-r0tl01kq	1723	3	two	two	CD
cord-010027-r0tl01kq	1723	4	air	air	NN
cord-010027-r0tl01kq	1723	5	dried	dry	VBN
cord-010027-r0tl01kq	1723	6	slides	slide	NNS
cord-010027-r0tl01kq	1723	7	,	,	,
cord-010027-r0tl01kq	1723	8	upon	upon	IN
cord-010027-r0tl01kq	1723	9	which	which	WDT
cord-010027-r0tl01kq	1723	10	a	a	DT
cord-010027-r0tl01kq	1723	11	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1723	12	of	of	IN
cord-010027-r0tl01kq	1723	13	mesenchymal	mesenchymal	JJ
cord-010027-r0tl01kq	1723	14	neoplasm	neoplasm	NN
cord-010027-r0tl01kq	1723	15	was	be	VBD
cord-010027-r0tl01kq	1723	16	made	make	VBN
cord-010027-r0tl01kq	1723	17	.	.	.
cord-010027-r0tl01kq	1724	1	The	the	DT
cord-010027-r0tl01kq	1724	2	patient	patient	NN
cord-010027-r0tl01kq	1724	3	underwent	undergo	VBD
cord-010027-r0tl01kq	1724	4	a	a	DT
cord-010027-r0tl01kq	1724	5	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1724	6	incisional	incisional	NNP
cord-010027-r0tl01kq	1724	7	biopsy	biopsy	NN
cord-010027-r0tl01kq	1724	8	allowing	allow	VBG
cord-010027-r0tl01kq	1724	9	a	a	DT
cord-010027-r0tl01kq	1724	10	formal	formal	JJ
cord-010027-r0tl01kq	1724	11	histological	histological	JJ
cord-010027-r0tl01kq	1724	12	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1724	13	of	of	IN
cord-010027-r0tl01kq	1724	14	myxoinflammatory	myxoinflammatory	NNP
cord-010027-r0tl01kq	1724	15	fibroblastic	fibroblastic	JJ
cord-010027-r0tl01kq	1724	16	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	1724	17	to	to	TO
cord-010027-r0tl01kq	1724	18	be	be	VB
cord-010027-r0tl01kq	1724	19	made	make	VBN
cord-010027-r0tl01kq	1724	20	.	.	.
cord-010027-r0tl01kq	1725	1	Myxoinflammatory	myxoinflammatory	JJ
cord-010027-r0tl01kq	1725	2	fibroblastic	fibroblastic	JJ
cord-010027-r0tl01kq	1725	3	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	1725	4	is	be	VBZ
cord-010027-r0tl01kq	1725	5	a	a	DT
cord-010027-r0tl01kq	1725	6	low	low	JJ
cord-010027-r0tl01kq	1725	7	-	-	HYPH
cord-010027-r0tl01kq	1725	8	grade	grade	NN
cord-010027-r0tl01kq	1725	9	neoplasm	neoplasm	NN
cord-010027-r0tl01kq	1725	10	usually	usually	RB
cord-010027-r0tl01kq	1725	11	occuring	occur	VBG
cord-010027-r0tl01kq	1725	12	on	on	IN
cord-010027-r0tl01kq	1725	13	the	the	DT
cord-010027-r0tl01kq	1725	14	distal	distal	JJ
cord-010027-r0tl01kq	1725	15	extremities	extremity	NNS
cord-010027-r0tl01kq	1725	16	and	and	CC
cord-010027-r0tl01kq	1725	17	only	only	RB
cord-010027-r0tl01kq	1725	18	rarely	rarely	RB
cord-010027-r0tl01kq	1725	19	presents	present	VBZ
cord-010027-r0tl01kq	1725	20	as	as	IN
cord-010027-r0tl01kq	1725	21	a	a	DT
cord-010027-r0tl01kq	1725	22	head	head	NN
cord-010027-r0tl01kq	1725	23	and	and	CC
cord-010027-r0tl01kq	1725	24	neck	neck	NN
cord-010027-r0tl01kq	1725	25	neoplasm	neoplasm	NN
cord-010027-r0tl01kq	1725	26	.	.	.
cord-010027-r0tl01kq	1726	1	FNA	FNA	NNP
cord-010027-r0tl01kq	1726	2	is	be	VBZ
cord-010027-r0tl01kq	1726	3	a	a	DT
cord-010027-r0tl01kq	1726	4	useful	useful	JJ
cord-010027-r0tl01kq	1726	5	tool	tool	NN
cord-010027-r0tl01kq	1726	6	in	in	IN
cord-010027-r0tl01kq	1726	7	the	the	DT
cord-010027-r0tl01kq	1726	8	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1726	9	and	and	CC
cord-010027-r0tl01kq	1726	10	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1726	11	management	management	NN
cord-010027-r0tl01kq	1726	12	of	of	IN
cord-010027-r0tl01kq	1726	13	head	head	NN
cord-010027-r0tl01kq	1726	14	and	and	CC
cord-010027-r0tl01kq	1726	15	neck	neck	NN
cord-010027-r0tl01kq	1726	16	neoplasia	neoplasia	NN
cord-010027-r0tl01kq	1726	17	and	and	CC
cord-010027-r0tl01kq	1726	18	we	-PRON-	PRP
cord-010027-r0tl01kq	1726	19	describe	describe	VBP
cord-010027-r0tl01kq	1726	20	here	here	RB
cord-010027-r0tl01kq	1726	21	the	the	DT
cord-010027-r0tl01kq	1726	22	cytological	cytological	JJ
cord-010027-r0tl01kq	1726	23	features	feature	NNS
cord-010027-r0tl01kq	1726	24	and	and	CC
cord-010027-r0tl01kq	1726	25	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1726	26	histological	histological	JJ
cord-010027-r0tl01kq	1726	27	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1726	28	of	of	IN
cord-010027-r0tl01kq	1726	29	myxoinflammatory	myxoinflammatory	NNP
cord-010027-r0tl01kq	1726	30	fibroblastic	fibroblastic	JJ
cord-010027-r0tl01kq	1726	31	sarcoma	sarcoma	NN
cord-010027-r0tl01kq	1726	32	occuring	occur	VBG
cord-010027-r0tl01kq	1726	33	in	in	IN
cord-010027-r0tl01kq	1726	34	the	the	DT
cord-010027-r0tl01kq	1726	35	occipital	occipital	JJ
cord-010027-r0tl01kq	1726	36	scalp	scalp	NN
cord-010027-r0tl01kq	1726	37	.	.	.
cord-010027-r0tl01kq	1727	1	Objective	objective	NN
cord-010027-r0tl01kq	1727	2	:	:	:
cord-010027-r0tl01kq	1727	3	Presentation	presentation	NN
cord-010027-r0tl01kq	1727	4	of	of	IN
cord-010027-r0tl01kq	1727	5	giant	giant	JJ
cord-010027-r0tl01kq	1727	6	cell	cell	NN
cord-010027-r0tl01kq	1727	7	fibroblastoma	fibroblastoma	NN
cord-010027-r0tl01kq	1727	8	(	(	-LRB-
cord-010027-r0tl01kq	1727	9	GCF	GCF	NNP
cord-010027-r0tl01kq	1727	10	)	)	-RRB-
cord-010027-r0tl01kq	1727	11	.	.	.
cord-010027-r0tl01kq	1728	1	Because	because	IN
cord-010027-r0tl01kq	1728	2	of	of	IN
cord-010027-r0tl01kq	1728	3	it	-PRON-	PRP
cord-010027-r0tl01kq	1728	4	has	have	VBZ
cord-010027-r0tl01kq	1728	5	a	a	DT
cord-010027-r0tl01kq	1728	6	dilemma	dilemma	NN
cord-010027-r0tl01kq	1728	7	of	of	IN
cord-010027-r0tl01kq	1728	8	microscopic	microscopic	JJ
cord-010027-r0tl01kq	1728	9	appearances	appearance	NNS
cord-010027-r0tl01kq	1728	10	;	;	:
cord-010027-r0tl01kq	1728	11	it	-PRON-	PRP
cord-010027-r0tl01kq	1728	12	is	be	VBZ
cord-010027-r0tl01kq	1728	13	mandatory	mandatory	JJ
cord-010027-r0tl01kq	1728	14	to	to	IN
cord-010027-r0tl01kq	1728	15	differentiating	differentiate	VBG
cord-010027-r0tl01kq	1728	16	it	-PRON-	PRP
cord-010027-r0tl01kq	1728	17	from	from	IN
cord-010027-r0tl01kq	1728	18	atypical	atypical	JJ
cord-010027-r0tl01kq	1728	19	dermatofibroma	dermatofibroma	NNP
cord-010027-r0tl01kq	1728	20	(	(	-LRB-
cord-010027-r0tl01kq	1728	21	ADF	ADF	NNP
cord-010027-r0tl01kq	1728	22	)	)	-RRB-
cord-010027-r0tl01kq	1728	23	,	,	,
cord-010027-r0tl01kq	1728	24	fibrous	fibrous	JJ
cord-010027-r0tl01kq	1728	25	hamartoma	hamartoma	NN
cord-010027-r0tl01kq	1728	26	of	of	IN
cord-010027-r0tl01kq	1728	27	infancy	infancy	NN
cord-010027-r0tl01kq	1728	28	(	(	-LRB-
cord-010027-r0tl01kq	1728	29	FHI	FHI	NNP
cord-010027-r0tl01kq	1728	30	)	)	-RRB-
cord-010027-r0tl01kq	1728	31	and	and	CC
cord-010027-r0tl01kq	1728	32	vascular	vascular	JJ
cord-010027-r0tl01kq	1728	33	lesions	lesion	NNS
cord-010027-r0tl01kq	1728	34	.	.	.
cord-010027-r0tl01kq	1729	1	Methods	method	NNS
cord-010027-r0tl01kq	1729	2	:	:	:
cord-010027-r0tl01kq	1729	3	Eighteen	eighteen	CD
cord-010027-r0tl01kq	1729	4	month	month	NN
cord-010027-r0tl01kq	1729	5	-	-	HYPH
cord-010027-r0tl01kq	1729	6	male	male	JJ
cord-010027-r0tl01kq	1729	7	Egyptian	egyptian	JJ
cord-010027-r0tl01kq	1729	8	child	child	NN
cord-010027-r0tl01kq	1729	9	presented	present	VBN
cord-010027-r0tl01kq	1729	10	with	with	IN
cord-010027-r0tl01kq	1729	11	painless	painless	JJ
cord-010027-r0tl01kq	1729	12	slowly	slowly	RB
cord-010027-r0tl01kq	1729	13	expanding	expand	VBG
cord-010027-r0tl01kq	1729	14	subcutaneous	subcutaneous	JJ
cord-010027-r0tl01kq	1729	15	back	back	JJ
cord-010027-r0tl01kq	1729	16	swelling	swell	VBG
cord-010027-r0tl01kq	1729	17	at	at	IN
cord-010027-r0tl01kq	1729	18	the	the	DT
cord-010027-r0tl01kq	1729	19	left	left	JJ
cord-010027-r0tl01kq	1729	20	scapular	scapular	JJ
cord-010027-r0tl01kq	1729	21	area	area	NN
cord-010027-r0tl01kq	1729	22	.	.	.
cord-010027-r0tl01kq	1730	1	Results	result	NNS
cord-010027-r0tl01kq	1730	2	:	:	:
cord-010027-r0tl01kq	1731	1	Histologically	histologically	RB
cord-010027-r0tl01kq	1731	2	,	,	,
cord-010027-r0tl01kq	1731	3	the	the	DT
cord-010027-r0tl01kq	1731	4	lesion	lesion	NN
cord-010027-r0tl01kq	1731	5	is	be	VBZ
cord-010027-r0tl01kq	1731	6	poorly	poorly	RB
cord-010027-r0tl01kq	1731	7	circumscribed	circumscribed	JJ
cord-010027-r0tl01kq	1731	8	and	and	CC
cord-010027-r0tl01kq	1731	9	range	range	VB
cord-010027-r0tl01kq	1731	10	from	from	IN
cord-010027-r0tl01kq	1731	11	cellular	cellular	JJ
cord-010027-r0tl01kq	1731	12	to	to	IN
cord-010027-r0tl01kq	1731	13	myxoid	myxoid	VB
cord-010027-r0tl01kq	1731	14	in	in	IN
cord-010027-r0tl01kq	1731	15	a	a	DT
cord-010027-r0tl01kq	1731	16	dense	dense	JJ
cord-010027-r0tl01kq	1731	17	to	to	IN
cord-010027-r0tl01kq	1731	18	loose	loose	JJ
cord-010027-r0tl01kq	1731	19	collagenous	collagenous	JJ
cord-010027-r0tl01kq	1731	20	stroma	stroma	NN
cord-010027-r0tl01kq	1731	21	.	.	.
cord-010027-r0tl01kq	1732	1	The	the	DT
cord-010027-r0tl01kq	1732	2	tumours	tumour	NNS
cord-010027-r0tl01kq	1732	3	composed	compose	VBN
cord-010027-r0tl01kq	1732	4	of	of	IN
cord-010027-r0tl01kq	1732	5	mixture	mixture	NN
cord-010027-r0tl01kq	1732	6	of	of	IN
cord-010027-r0tl01kq	1732	7	spindle	spindle	NN
cord-010027-r0tl01kq	1732	8	shaped	shape	VBN
cord-010027-r0tl01kq	1732	9	or	or	CC
cord-010027-r0tl01kq	1732	10	stellate	stellate	JJ
cord-010027-r0tl01kq	1732	11	cells	cell	NNS
cord-010027-r0tl01kq	1732	12	admixed	admix	VBN
cord-010027-r0tl01kq	1732	13	with	with	IN
cord-010027-r0tl01kq	1732	14	multinucleated	multinucleated	JJ
cord-010027-r0tl01kq	1732	15	giant	giant	JJ
cord-010027-r0tl01kq	1732	16	cells	cell	NNS
cord-010027-r0tl01kq	1732	17	with	with	IN
cord-010027-r0tl01kq	1732	18	occasional	occasional	JJ
cord-010027-r0tl01kq	1732	19	pleomorphism	pleomorphism	NN
cord-010027-r0tl01kq	1732	20	and	and	CC
cord-010027-r0tl01kq	1732	21	very	very	RB
cord-010027-r0tl01kq	1732	22	low	low	JJ
cord-010027-r0tl01kq	1732	23	mitotic	mitotic	JJ
cord-010027-r0tl01kq	1732	24	index	index	NN
cord-010027-r0tl01kq	1732	25	(	(	-LRB-
cord-010027-r0tl01kq	1732	26	<	<	NNP
cord-010027-r0tl01kq	1732	27	1	1	CD
cord-010027-r0tl01kq	1732	28	per	per	IN
cord-010027-r0tl01kq	1732	29	50	50	CD
cord-010027-r0tl01kq	1732	30	high	high	JJ
cord-010027-r0tl01kq	1732	31	-	-	HYPH
cord-010027-r0tl01kq	1732	32	power	power	NN
cord-010027-r0tl01kq	1732	33	fields	field	NNS
cord-010027-r0tl01kq	1732	34	)	)	-RRB-
cord-010027-r0tl01kq	1732	35	.	.	.
cord-010027-r0tl01kq	1733	1	These	these	DT
cord-010027-r0tl01kq	1733	2	cells	cell	NNS
cord-010027-r0tl01kq	1733	3	infiltrate	infiltrate	VBP
cord-010027-r0tl01kq	1733	4	around	around	IN
cord-010027-r0tl01kq	1733	5	adnexal	adnexal	NN
cord-010027-r0tl01kq	1733	6	structures	structure	NNS
cord-010027-r0tl01kq	1733	7	and	and	CC
cord-010027-r0tl01kq	1733	8	through	through	IN
cord-010027-r0tl01kq	1733	9	subcutaneous	subcutaneous	JJ
cord-010027-r0tl01kq	1733	10	fat	fat	NN
cord-010027-r0tl01kq	1733	11	.	.	.
cord-010027-r0tl01kq	1734	1	A	a	DT
cord-010027-r0tl01kq	1734	2	distinctive	distinctive	JJ
cord-010027-r0tl01kq	1734	3	finding	finding	NN
cord-010027-r0tl01kq	1734	4	is	be	VBZ
cord-010027-r0tl01kq	1734	5	cracking	crack	VBG
cord-010027-r0tl01kq	1734	6	artifact	artifact	NN
cord-010027-r0tl01kq	1734	7	of	of	IN
cord-010027-r0tl01kq	1734	8	the	the	DT
cord-010027-r0tl01kq	1734	9	stroma	stroma	NN
cord-010027-r0tl01kq	1734	10	simulating	simulate	VBG
cord-010027-r0tl01kq	1734	11	angiectoid	angiectoid	NNP
cord-010027-r0tl01kq	1734	12	spaces	space	NNS
cord-010027-r0tl01kq	1734	13	.	.	.
cord-010027-r0tl01kq	1735	1	These	these	DT
cord-010027-r0tl01kq	1735	2	pseudovascular	pseudovascular	JJ
cord-010027-r0tl01kq	1735	3	spaces	space	NNS
cord-010027-r0tl01kq	1735	4	are	be	VBP
cord-010027-r0tl01kq	1735	5	lacking	lack	VBG
cord-010027-r0tl01kq	1735	6	a	a	DT
cord-010027-r0tl01kq	1735	7	true	true	JJ
cord-010027-r0tl01kq	1735	8	endothelial	endothelial	JJ
cord-010027-r0tl01kq	1735	9	lining	lining	NN
cord-010027-r0tl01kq	1735	10	and	and	CC
cord-010027-r0tl01kq	1735	11	lined	line	VBN
cord-010027-r0tl01kq	1735	12	by	by	IN
cord-010027-r0tl01kq	1735	13	discontinuous	discontinuous	JJ
cord-010027-r0tl01kq	1735	14	layer	layer	NN
cord-010027-r0tl01kq	1735	15	of	of	IN
cord-010027-r0tl01kq	1735	16	enlarged	enlarged	JJ
cord-010027-r0tl01kq	1735	17	multinucleated	multinucleated	JJ
cord-010027-r0tl01kq	1735	18	giant	giant	JJ
cord-010027-r0tl01kq	1735	19	cells	cell	NNS
cord-010027-r0tl01kq	1735	20	.	.	.
cord-010027-r0tl01kq	1736	1	Immunostains	Immunostains	NNP
cord-010027-r0tl01kq	1736	2	,	,	,
cord-010027-r0tl01kq	1736	3	including	include	VBG
cord-010027-r0tl01kq	1736	4	factor	factor	NN
cord-010027-r0tl01kq	1736	5	VIII	VIII	NNP
cord-010027-r0tl01kq	1736	6	,	,	,
cord-010027-r0tl01kq	1736	7	CD31	CD31	NNP
cord-010027-r0tl01kq	1736	8	,	,	,
cord-010027-r0tl01kq	1736	9	CD1a	CD1a	NNP
cord-010027-r0tl01kq	1736	10	,	,	,
cord-010027-r0tl01kq	1736	11	SMA	SMA	NNP
cord-010027-r0tl01kq	1736	12	,	,	,
cord-010027-r0tl01kq	1736	13	S100	S100	NNP
cord-010027-r0tl01kq	1736	14	and	and	CC
cord-010027-r0tl01kq	1736	15	CD68	CD68	NNP
cord-010027-r0tl01kq	1736	16	were	be	VBD
cord-010027-r0tl01kq	1736	17	negative	negative	JJ
cord-010027-r0tl01kq	1736	18	.	.	.
cord-010027-r0tl01kq	1737	1	Ki	Ki	NNP
cord-010027-r0tl01kq	1737	2	67	67	CD
cord-010027-r0tl01kq	1737	3	labeling	labeling	NN
cord-010027-r0tl01kq	1737	4	index	index	NN
cord-010027-r0tl01kq	1737	5	is	be	VBZ
cord-010027-r0tl01kq	1737	6	very	very	RB
cord-010027-r0tl01kq	1737	7	low	low	JJ
cord-010027-r0tl01kq	1737	8	.	.	.
cord-010027-r0tl01kq	1738	1	All	all	PDT
cord-010027-r0tl01kq	1738	2	the	the	DT
cord-010027-r0tl01kq	1738	3	cellular	cellular	JJ
cord-010027-r0tl01kq	1738	4	components	component	NNS
cord-010027-r0tl01kq	1738	5	show	show	VBP
cord-010027-r0tl01kq	1738	6	positive	positive	JJ
cord-010027-r0tl01kq	1738	7	immunoreactivity	immunoreactivity	NN
cord-010027-r0tl01kq	1738	8	for	for	IN
cord-010027-r0tl01kq	1738	9	CD34	CD34	NNP
cord-010027-r0tl01kq	1738	10	.	.	.
cord-010027-r0tl01kq	1739	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1739	2	:	:	:
cord-010027-r0tl01kq	1740	1	First	first	JJ
cord-010027-r0tl01kq	1740	2	case	case	NN
cord-010027-r0tl01kq	1740	3	of	of	IN
cord-010027-r0tl01kq	1740	4	GCF	GCF	NNP
cord-010027-r0tl01kq	1740	5	reported	report	VBN
cord-010027-r0tl01kq	1740	6	in	in	IN
cord-010027-r0tl01kq	1740	7	Egypt	Egypt	NNP
cord-010027-r0tl01kq	1740	8	.	.	.
cord-010027-r0tl01kq	1741	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1741	2	recommend	recommend	VBP
cord-010027-r0tl01kq	1741	3	a	a	DT
cord-010027-r0tl01kq	1741	4	wide	wide	JJ
cord-010027-r0tl01kq	1741	5	scaled	scale	VBN
cord-010027-r0tl01kq	1741	6	study	study	NN
cord-010027-r0tl01kq	1741	7	to	to	TO
cord-010027-r0tl01kq	1741	8	categorize	categorize	VB
cord-010027-r0tl01kq	1741	9	this	this	DT
cord-010027-r0tl01kq	1741	10	tumour	tumour	NN
cord-010027-r0tl01kq	1741	11	with	with	IN
cord-010027-r0tl01kq	1741	12	molecularly	molecularly	RB
cord-010027-r0tl01kq	1741	13	similar	similar	JJ
cord-010027-r0tl01kq	1741	14	lesions	lesion	NNS
cord-010027-r0tl01kq	1741	15	.	.	.
cord-010027-r0tl01kq	1742	1	The	the	DT
cord-010027-r0tl01kq	1742	2	Royal	Royal	NNP
cord-010027-r0tl01kq	1742	3	County	County	NNP
cord-010027-r0tl01kq	1742	4	Sussex	Sussex	NNP
cord-010027-r0tl01kq	1742	5	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1742	6	,	,	,
cord-010027-r0tl01kq	1742	7	Brighton	Brighton	NNP
cord-010027-r0tl01kq	1742	8	,	,	,
cord-010027-r0tl01kq	1742	9	UK	UK	NNP
cord-010027-r0tl01kq	1742	10	A	A	NNP
cord-010027-r0tl01kq	1742	11	60	60	CD
cord-010027-r0tl01kq	1742	12	year	year	NN
cord-010027-r0tl01kq	1742	13	old	old	JJ
cord-010027-r0tl01kq	1742	14	man	man	NN
cord-010027-r0tl01kq	1742	15	being	be	VBG
cord-010027-r0tl01kq	1742	16	investigated	investigate	VBN
cord-010027-r0tl01kq	1742	17	for	for	IN
cord-010027-r0tl01kq	1742	18	obstructive	obstructive	JJ
cord-010027-r0tl01kq	1742	19	hydronephrosis	hydronephrosis	NN
cord-010027-r0tl01kq	1742	20	was	be	VBD
cord-010027-r0tl01kq	1742	21	incidentally	incidentally	RB
cord-010027-r0tl01kq	1742	22	found	find	VBN
cord-010027-r0tl01kq	1742	23	to	to	TO
cord-010027-r0tl01kq	1742	24	have	have	VB
cord-010027-r0tl01kq	1742	25	a	a	DT
cord-010027-r0tl01kq	1742	26	3.2	3.2	CD
cord-010027-r0tl01kq	1742	27	cm	cm	NN
cord-010027-r0tl01kq	1742	28	splenic	splenic	JJ
cord-010027-r0tl01kq	1742	29	mass	mass	NN
cord-010027-r0tl01kq	1742	30	on	on	IN
cord-010027-r0tl01kq	1742	31	computed	compute	VBN
cord-010027-r0tl01kq	1742	32	tomography	tomography	NN
cord-010027-r0tl01kq	1742	33	(	(	-LRB-
cord-010027-r0tl01kq	1742	34	CT	CT	NNP
cord-010027-r0tl01kq	1742	35	)	)	-RRB-
cord-010027-r0tl01kq	1742	36	.	.	.
cord-010027-r0tl01kq	1743	1	No	no	DT
cord-010027-r0tl01kq	1743	2	lymphadenopathy	lymphadenopathy	NN
cord-010027-r0tl01kq	1743	3	was	be	VBD
cord-010027-r0tl01kq	1743	4	present	present	JJ
cord-010027-r0tl01kq	1743	5	and	and	CC
cord-010027-r0tl01kq	1743	6	the	the	DT
cord-010027-r0tl01kq	1743	7	mass	mass	NN
cord-010027-r0tl01kq	1743	8	remained	remain	VBD
cord-010027-r0tl01kq	1743	9	stable	stable	JJ
cord-010027-r0tl01kq	1743	10	on	on	IN
cord-010027-r0tl01kq	1743	11	sequential	sequential	JJ
cord-010027-r0tl01kq	1743	12	CT	ct	NN
cord-010027-r0tl01kq	1743	13	and	and	CC
cord-010027-r0tl01kq	1743	14	ultrasound	ultrasound	NN
cord-010027-r0tl01kq	1743	15	scans	scan	NNS
cord-010027-r0tl01kq	1743	16	.	.	.
cord-010027-r0tl01kq	1744	1	On	on	IN
cord-010027-r0tl01kq	1744	2	positron	positron	NN
cord-010027-r0tl01kq	1744	3	emission	emission	NN
cord-010027-r0tl01kq	1744	4	tomography	tomography	NN
cord-010027-r0tl01kq	1744	5	(	(	-LRB-
cord-010027-r0tl01kq	1744	6	PET	pet	NN
cord-010027-r0tl01kq	1744	7	)	)	-RRB-
cord-010027-r0tl01kq	1744	8	the	the	DT
cord-010027-r0tl01kq	1744	9	lesion	lesion	NN
cord-010027-r0tl01kq	1744	10	had	have	VBD
cord-010027-r0tl01kq	1744	11	a	a	DT
cord-010027-r0tl01kq	1744	12	low	low	JJ
cord-010027-r0tl01kq	1744	13	signal	signal	NN
cord-010027-r0tl01kq	1744	14	with	with	IN
cord-010027-r0tl01kq	1744	15	moderate	moderate	JJ
cord-010027-r0tl01kq	1744	16	uptake	uptake	NN
cord-010027-r0tl01kq	1744	17	.	.	.
cord-010027-r0tl01kq	1745	1	All	all	DT
cord-010027-r0tl01kq	1745	2	haematological	haematological	JJ
cord-010027-r0tl01kq	1745	3	investigations	investigation	NNS
cord-010027-r0tl01kq	1745	4	were	be	VBD
cord-010027-r0tl01kq	1745	5	within	within	IN
cord-010027-r0tl01kq	1745	6	normal	normal	JJ
cord-010027-r0tl01kq	1745	7	limits	limit	NNS
cord-010027-r0tl01kq	1745	8	including	include	VBG
cord-010027-r0tl01kq	1745	9	a	a	DT
cord-010027-r0tl01kq	1745	10	negative	negative	JJ
cord-010027-r0tl01kq	1745	11	Epstein	Epstein	NNP
cord-010027-r0tl01kq	1745	12	Barr	Barr	NNP
cord-010027-r0tl01kq	1745	13	Virus	Virus	NNP
cord-010027-r0tl01kq	1745	14	(	(	-LRB-
cord-010027-r0tl01kq	1745	15	EBV	EBV	NNP
cord-010027-r0tl01kq	1745	16	)	)	-RRB-
cord-010027-r0tl01kq	1745	17	test	test	NN
cord-010027-r0tl01kq	1745	18	.	.	.
cord-010027-r0tl01kq	1746	1	His	-PRON-	PRP$
cord-010027-r0tl01kq	1746	2	past	past	JJ
cord-010027-r0tl01kq	1746	3	medical	medical	JJ
cord-010027-r0tl01kq	1746	4	history	history	NN
cord-010027-r0tl01kq	1746	5	included	include	VBD
cord-010027-r0tl01kq	1746	6	previous	previous	JJ
cord-010027-r0tl01kq	1746	7	immunosuppressive	immunosuppressive	JJ
cord-010027-r0tl01kq	1746	8	therapy	therapy	NN
cord-010027-r0tl01kq	1746	9	for	for	IN
cord-010027-r0tl01kq	1746	10	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	1746	11	bowel	bowel	NN
cord-010027-r0tl01kq	1746	12	disease	disease	NN
cord-010027-r0tl01kq	1746	13	.	.	.
cord-010027-r0tl01kq	1747	1	A	a	DT
cord-010027-r0tl01kq	1747	2	core	core	NN
cord-010027-r0tl01kq	1747	3	biopsy	biopsy	NN
cord-010027-r0tl01kq	1747	4	under	under	IN
cord-010027-r0tl01kq	1747	5	CT	CT	NNP
cord-010027-r0tl01kq	1747	6	guidance	guidance	NN
cord-010027-r0tl01kq	1747	7	was	be	VBD
cord-010027-r0tl01kq	1747	8	performed	perform	VBN
cord-010027-r0tl01kq	1747	9	.	.	.
cord-010027-r0tl01kq	1748	1	The	the	DT
cord-010027-r0tl01kq	1748	2	cores	core	NNS
cord-010027-r0tl01kq	1748	3	showed	show	VBD
cord-010027-r0tl01kq	1748	4	a	a	DT
cord-010027-r0tl01kq	1748	5	paucicellular	paucicellular	JJ
cord-010027-r0tl01kq	1748	6	spindle	spindle	NN
cord-010027-r0tl01kq	1748	7	cell	cell	NN
cord-010027-r0tl01kq	1748	8	lesion	lesion	NN
cord-010027-r0tl01kq	1748	9	with	with	IN
cord-010027-r0tl01kq	1748	10	bland	bland	JJ
cord-010027-r0tl01kq	1748	11	,	,	,
cord-010027-r0tl01kq	1748	12	blunt	blunt	JJ
cord-010027-r0tl01kq	1748	13	ended	ended	JJ
cord-010027-r0tl01kq	1748	14	nuclei	nucleus	NNS
cord-010027-r0tl01kq	1748	15	,	,	,
cord-010027-r0tl01kq	1748	16	no	no	DT
cord-010027-r0tl01kq	1748	17	cytological	cytological	JJ
cord-010027-r0tl01kq	1748	18	atypia	atypia	NN
cord-010027-r0tl01kq	1748	19	and	and	CC
cord-010027-r0tl01kq	1748	20	a	a	DT
cord-010027-r0tl01kq	1748	21	sparse	sparse	JJ
cord-010027-r0tl01kq	1748	22	chronic	chronic	JJ
cord-010027-r0tl01kq	1748	23	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	1748	24	infiltrate	infiltrate	NN
cord-010027-r0tl01kq	1748	25	.	.	.
cord-010027-r0tl01kq	1749	1	There	there	EX
cord-010027-r0tl01kq	1749	2	was	be	VBD
cord-010027-r0tl01kq	1749	3	no	no	DT
cord-010027-r0tl01kq	1749	4	necrosis	necrosis	NN
cord-010027-r0tl01kq	1749	5	.	.	.
cord-010027-r0tl01kq	1750	1	The	the	DT
cord-010027-r0tl01kq	1750	2	spindle	spindle	NN
cord-010027-r0tl01kq	1750	3	cells	cell	NNS
cord-010027-r0tl01kq	1750	4	stained	stain	VBD
cord-010027-r0tl01kq	1750	5	positive	positive	JJ
cord-010027-r0tl01kq	1750	6	for	for	IN
cord-010027-r0tl01kq	1750	7	smooth	smooth	JJ
cord-010027-r0tl01kq	1750	8	muscle	muscle	NN
cord-010027-r0tl01kq	1750	9	actin	actin	NN
cord-010027-r0tl01kq	1750	10	(	(	-LRB-
cord-010027-r0tl01kq	1750	11	SMA	SMA	NNP
cord-010027-r0tl01kq	1750	12	)	)	-RRB-
cord-010027-r0tl01kq	1750	13	and	and	CC
cord-010027-r0tl01kq	1750	14	H	H	NNP
cord-010027-r0tl01kq	1750	15	-	-	HYPH
cord-010027-r0tl01kq	1750	16	Caldesmon	Caldesmon	NNP
cord-010027-r0tl01kq	1750	17	indicating	indicate	VBG
cord-010027-r0tl01kq	1750	18	this	this	DT
cord-010027-r0tl01kq	1750	19	to	to	TO
cord-010027-r0tl01kq	1750	20	be	be	VB
cord-010027-r0tl01kq	1750	21	a	a	DT
cord-010027-r0tl01kq	1750	22	splenic	splenic	JJ
cord-010027-r0tl01kq	1750	23	leiomyoma	leiomyoma	NN
cord-010027-r0tl01kq	1750	24	.	.	.
cord-010027-r0tl01kq	1751	1	Splenic	splenic	JJ
cord-010027-r0tl01kq	1751	2	lesions	lesion	NNS
cord-010027-r0tl01kq	1751	3	are	be	VBP
cord-010027-r0tl01kq	1751	4	uncommon	uncommon	JJ
cord-010027-r0tl01kq	1751	5	and	and	CC
cord-010027-r0tl01kq	1751	6	within	within	IN
cord-010027-r0tl01kq	1751	7	their	-PRON-	PRP$
cord-010027-r0tl01kq	1751	8	differential	differential	NN
cord-010027-r0tl01kq	1751	9	include	include	VBP
cord-010027-r0tl01kq	1751	10	,	,	,
cord-010027-r0tl01kq	1751	11	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1751	12	,	,	,
cord-010027-r0tl01kq	1751	13	inflammatory	inflammatory	JJ
cord-010027-r0tl01kq	1751	14	pseudotumour	pseudotumour	NN
cord-010027-r0tl01kq	1751	15	,	,	,
cord-010027-r0tl01kq	1751	16	harmatomas	harmatomas	NNP
cord-010027-r0tl01kq	1751	17	and	and	CC
cord-010027-r0tl01kq	1751	18	leiomyomas	leiomyomas	NNP
cord-010027-r0tl01kq	1751	19	.	.	.
cord-010027-r0tl01kq	1752	1	(	(	-LRB-
cord-010027-r0tl01kq	1752	2	1	1	CD
cord-010027-r0tl01kq	1752	3	)	)	-RRB-
cord-010027-r0tl01kq	1753	1	A	a	DT
cord-010027-r0tl01kq	1753	2	splenic	splenic	JJ
cord-010027-r0tl01kq	1753	3	leiomyoma	leiomyoma	NN
cord-010027-r0tl01kq	1753	4	is	be	VBZ
cord-010027-r0tl01kq	1753	5	an	an	DT
cord-010027-r0tl01kq	1753	6	unusual	unusual	JJ
cord-010027-r0tl01kq	1753	7	and	and	CC
cord-010027-r0tl01kq	1753	8	rare	rare	JJ
cord-010027-r0tl01kq	1753	9	benign	benign	JJ
cord-010027-r0tl01kq	1753	10	smooth	smooth	JJ
cord-010027-r0tl01kq	1753	11	muscle	muscle	NN
cord-010027-r0tl01kq	1753	12	tumour	tumour	NN
cord-010027-r0tl01kq	1753	13	with	with	IN
cord-010027-r0tl01kq	1753	14	an	an	DT
cord-010027-r0tl01kq	1753	15	unknown	unknown	JJ
cord-010027-r0tl01kq	1753	16	pathogenesis	pathogenesis	NN
cord-010027-r0tl01kq	1753	17	.	.	.
cord-010027-r0tl01kq	1754	1	They	-PRON-	PRP
cord-010027-r0tl01kq	1754	2	are	be	VBP
cord-010027-r0tl01kq	1754	3	thought	think	VBN
cord-010027-r0tl01kq	1754	4	to	to	TO
cord-010027-r0tl01kq	1754	5	arise	arise	VB
cord-010027-r0tl01kq	1754	6	from	from	IN
cord-010027-r0tl01kq	1754	7	the	the	DT
cord-010027-r0tl01kq	1754	8	capsule	capsule	NN
cord-010027-r0tl01kq	1754	9	and	and	CC
cord-010027-r0tl01kq	1754	10	blood	blood	NN
cord-010027-r0tl01kq	1754	11	vessel	vessel	NN
cord-010027-r0tl01kq	1754	12	walls	wall	NNS
cord-010027-r0tl01kq	1754	13	of	of	IN
cord-010027-r0tl01kq	1754	14	organs	organ	NNS
cord-010027-r0tl01kq	1754	15	.	.	.
cord-010027-r0tl01kq	1755	1	(	(	-LRB-
cord-010027-r0tl01kq	1755	2	2	2	LS
cord-010027-r0tl01kq	1755	3	)	)	-RRB-
cord-010027-r0tl01kq	1755	4	They	-PRON-	PRP
cord-010027-r0tl01kq	1755	5	have	have	VBP
cord-010027-r0tl01kq	1755	6	been	be	VBN
cord-010027-r0tl01kq	1755	7	documented	document	VBN
cord-010027-r0tl01kq	1755	8	in	in	IN
cord-010027-r0tl01kq	1755	9	immunosuppressed	immunosuppressed	JJ
cord-010027-r0tl01kq	1755	10	states	state	NNS
cord-010027-r0tl01kq	1755	11	(	(	-LRB-
cord-010027-r0tl01kq	1755	12	constitutional	constitutional	JJ
cord-010027-r0tl01kq	1755	13	or	or	CC
cord-010027-r0tl01kq	1755	14	acquired	acquire	VBN
cord-010027-r0tl01kq	1755	15	)	)	-RRB-
cord-010027-r0tl01kq	1755	16	,	,	,
cord-010027-r0tl01kq	1755	17	in	in	IN
cord-010027-r0tl01kq	1755	18	those	those	DT
cord-010027-r0tl01kq	1755	19	with	with	IN
cord-010027-r0tl01kq	1755	20	EBV	EBV	NNP
cord-010027-r0tl01kq	1755	21	infection	infection	NN
cord-010027-r0tl01kq	1755	22	and	and	CC
cord-010027-r0tl01kq	1755	23	in	in	IN
cord-010027-r0tl01kq	1755	24	children	child	NNS
cord-010027-r0tl01kq	1755	25	with	with	IN
cord-010027-r0tl01kq	1755	26	ataxia	ataxia	NN
cord-010027-r0tl01kq	1755	27	-	-	HYPH
cord-010027-r0tl01kq	1755	28	telangiectasia	telangiectasia	NN
cord-010027-r0tl01kq	1755	29	.	.	.
cord-010027-r0tl01kq	1756	1	(	(	-LRB-
cord-010027-r0tl01kq	1756	2	2	2	LS
cord-010027-r0tl01kq	1756	3	)	)	-RRB-
cord-010027-r0tl01kq	1756	4	Leiomyomas	Leiomyomas	NNP
cord-010027-r0tl01kq	1756	5	within	within	IN
cord-010027-r0tl01kq	1756	6	the	the	DT
cord-010027-r0tl01kq	1756	7	spleen	spleen	NNS
cord-010027-r0tl01kq	1756	8	are	be	VBP
cord-010027-r0tl01kq	1756	9	rarely	rarely	RB
cord-010027-r0tl01kq	1756	10	reported	report	VBN
cord-010027-r0tl01kq	1756	11	in	in	IN
cord-010027-r0tl01kq	1756	12	the	the	DT
cord-010027-r0tl01kq	1756	13	literature	literature	NN
cord-010027-r0tl01kq	1756	14	,	,	,
cord-010027-r0tl01kq	1756	15	especially	especially	RB
cord-010027-r0tl01kq	1756	16	in	in	IN
cord-010027-r0tl01kq	1756	17	those	those	DT
cord-010027-r0tl01kq	1756	18	patients	patient	NNS
cord-010027-r0tl01kq	1756	19	over	over	IN
cord-010027-r0tl01kq	1756	20	the	the	DT
cord-010027-r0tl01kq	1756	21	age	age	NN
cord-010027-r0tl01kq	1756	22	of	of	IN
cord-010027-r0tl01kq	1756	23	eighteen	eighteen	CD
cord-010027-r0tl01kq	1756	24	.	.	.
cord-010027-r0tl01kq	1757	1	In	in	IN
cord-010027-r0tl01kq	1757	2	this	this	DT
cord-010027-r0tl01kq	1757	3	case	case	NN
cord-010027-r0tl01kq	1757	4	there	there	EX
cord-010027-r0tl01kq	1757	5	was	be	VBD
cord-010027-r0tl01kq	1757	6	historical	historical	JJ
cord-010027-r0tl01kq	1757	7	immunosuppression	immunosuppression	NN
cord-010027-r0tl01kq	1757	8	,	,	,
cord-010027-r0tl01kq	1757	9	however	however	RB
cord-010027-r0tl01kq	1757	10	leiomyomas	leiomyomas	NNP
cord-010027-r0tl01kq	1757	11	should	should	MD
cord-010027-r0tl01kq	1757	12	be	be	VB
cord-010027-r0tl01kq	1757	13	considered	consider	VBN
cord-010027-r0tl01kq	1757	14	in	in	IN
cord-010027-r0tl01kq	1757	15	the	the	DT
cord-010027-r0tl01kq	1757	16	differential	differential	JJ
cord-010027-r0tl01kq	1757	17	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1757	18	of	of	IN
cord-010027-r0tl01kq	1757	19	well	well	RB
cord-010027-r0tl01kq	1757	20	-	-	HYPH
cord-010027-r0tl01kq	1757	21	defined	define	VBN
cord-010027-r0tl01kq	1757	22	solitary	solitary	JJ
cord-010027-r0tl01kq	1757	23	splenic	splenic	JJ
cord-010027-r0tl01kq	1757	24	lesions	lesion	NNS
cord-010027-r0tl01kq	1757	25	Purpose	Purpose	NNP
cord-010027-r0tl01kq	1757	26	of	of	IN
cord-010027-r0tl01kq	1757	27	the	the	DT
cord-010027-r0tl01kq	1757	28	Study	study	NN
cord-010027-r0tl01kq	1757	29	:	:	:
cord-010027-r0tl01kq	1758	1	The	the	DT
cord-010027-r0tl01kq	1758	2	Zucker	Zucker	NNP
cord-010027-r0tl01kq	1758	3	Diabetic	diabetic	JJ
cord-010027-r0tl01kq	1758	4	Fatty	Fatty	NNP
cord-010027-r0tl01kq	1758	5	(	(	-LRB-
cord-010027-r0tl01kq	1758	6	ZDF	ZDF	NNP
cord-010027-r0tl01kq	1758	7	)	)	-RRB-
cord-010027-r0tl01kq	1758	8	rat	rat	NN
cord-010027-r0tl01kq	1758	9	is	be	VBZ
cord-010027-r0tl01kq	1758	10	extensively	extensively	RB
cord-010027-r0tl01kq	1758	11	used	use	VBN
cord-010027-r0tl01kq	1758	12	as	as	IN
cord-010027-r0tl01kq	1758	13	a	a	DT
cord-010027-r0tl01kq	1758	14	model	model	NN
cord-010027-r0tl01kq	1758	15	of	of	IN
cord-010027-r0tl01kq	1758	16	Diabetic	diabetic	JJ
cord-010027-r0tl01kq	1758	17	Kidney	Kidney	NNP
cord-010027-r0tl01kq	1758	18	Disease	Disease	NNP
cord-010027-r0tl01kq	1758	19	(	(	-LRB-
cord-010027-r0tl01kq	1758	20	DKD	DKD	NNP
cord-010027-r0tl01kq	1758	21	)	)	-RRB-
cord-010027-r0tl01kq	1758	22	associated	associate	VBN
cord-010027-r0tl01kq	1758	23	with	with	IN
cord-010027-r0tl01kq	1758	24	obesity	obesity	NN
cord-010027-r0tl01kq	1758	25	and	and	CC
cord-010027-r0tl01kq	1758	26	progressive	progressive	JJ
cord-010027-r0tl01kq	1758	27	insulin	insulin	NN
cord-010027-r0tl01kq	1758	28	resistance	resistance	NN
cord-010027-r0tl01kq	1758	29	(	(	-LRB-
cord-010027-r0tl01kq	1758	30	'	'	``
cord-010027-r0tl01kq	1758	31	diabesity	diabesity	NN
cord-010027-r0tl01kq	1758	32	'	'	''
cord-010027-r0tl01kq	1758	33	)	)	-RRB-
cord-010027-r0tl01kq	1758	34	.	.	.
cord-010027-r0tl01kq	1759	1	This	this	DT
cord-010027-r0tl01kq	1759	2	study	study	NN
cord-010027-r0tl01kq	1759	3	aimed	aim	VBD
cord-010027-r0tl01kq	1759	4	to	to	TO
cord-010027-r0tl01kq	1759	5	validate	validate	VB
cord-010027-r0tl01kq	1759	6	qualitative	qualitative	JJ
cord-010027-r0tl01kq	1759	7	ultrastructural	ultrastructural	JJ
cord-010027-r0tl01kq	1759	8	parameters	parameter	NNS
cord-010027-r0tl01kq	1759	9	of	of	IN
cord-010027-r0tl01kq	1759	10	glomerular	glomerular	JJ
cord-010027-r0tl01kq	1759	11	injury	injury	NN
cord-010027-r0tl01kq	1759	12	in	in	IN
cord-010027-r0tl01kq	1759	13	the	the	DT
cord-010027-r0tl01kq	1759	14	ZDF	ZDF	NNP
cord-010027-r0tl01kq	1759	15	animal	animal	NN
cord-010027-r0tl01kq	1759	16	model	model	NN
cord-010027-r0tl01kq	1759	17	and	and	CC
cord-010027-r0tl01kq	1759	18	apply	apply	VB
cord-010027-r0tl01kq	1759	19	these	these	DT
cord-010027-r0tl01kq	1759	20	criteria	criterion	NNS
cord-010027-r0tl01kq	1759	21	to	to	IN
cord-010027-r0tl01kq	1759	22	an	an	DT
cord-010027-r0tl01kq	1759	23	interventional	interventional	JJ
cord-010027-r0tl01kq	1759	24	study	study	NN
cord-010027-r0tl01kq	1759	25	investigating	investigate	VBG
cord-010027-r0tl01kq	1759	26	the	the	DT
cord-010027-r0tl01kq	1759	27	effects	effect	NNS
cord-010027-r0tl01kq	1759	28	of	of	IN
cord-010027-r0tl01kq	1759	29	Roux	roux	NN
cord-010027-r0tl01kq	1759	30	-	-	HYPH
cord-010027-r0tl01kq	1759	31	en	en	FW
cord-010027-r0tl01kq	1759	32	-	-	HYPH
cord-010027-r0tl01kq	1759	33	Y	Y	NNP
cord-010027-r0tl01kq	1759	34	gastric	gastric	JJ
cord-010027-r0tl01kq	1759	35	bypass	bypass	NN
cord-010027-r0tl01kq	1759	36	(	(	-LRB-
cord-010027-r0tl01kq	1759	37	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1759	38	)	)	-RRB-
cord-010027-r0tl01kq	1759	39	on	on	IN
cord-010027-r0tl01kq	1759	40	DKD	DKD	NNP
cord-010027-r0tl01kq	1759	41	.	.	.
cord-010027-r0tl01kq	1760	1	Methods	method	NNS
cord-010027-r0tl01kq	1760	2	:	:	:
cord-010027-r0tl01kq	1761	1	Superficial	superficial	JJ
cord-010027-r0tl01kq	1761	2	renal	renal	JJ
cord-010027-r0tl01kq	1761	3	cortices	cortex	NNS
cord-010027-r0tl01kq	1761	4	were	be	VBD
cord-010027-r0tl01kq	1761	5	immersion	immersion	NN
cord-010027-r0tl01kq	1761	6	-	-	HYPH
cord-010027-r0tl01kq	1761	7	fixed	fix	VBN
cord-010027-r0tl01kq	1761	8	in	in	IN
cord-010027-r0tl01kq	1761	9	2.5	2.5	CD
cord-010027-r0tl01kq	1761	10	%	%	NN
cord-010027-r0tl01kq	1761	11	glutaraldehyde	glutaraldehyde	NN
cord-010027-r0tl01kq	1761	12	,	,	,
cord-010027-r0tl01kq	1761	13	post	post	JJ
cord-010027-r0tl01kq	1761	14	-	-	JJ
cord-010027-r0tl01kq	1761	15	fixed	fix	VBN
cord-010027-r0tl01kq	1761	16	in	in	IN
cord-010027-r0tl01kq	1761	17	1	1	CD
cord-010027-r0tl01kq	1761	18	%	%	NN
cord-010027-r0tl01kq	1761	19	osmium	osmium	NN
cord-010027-r0tl01kq	1761	20	tetroxide	tetroxide	NN
cord-010027-r0tl01kq	1761	21	,	,	,
cord-010027-r0tl01kq	1761	22	processed	process	VBN
cord-010027-r0tl01kq	1761	23	and	and	CC
cord-010027-r0tl01kq	1761	24	embedded	embed	VBN
cord-010027-r0tl01kq	1761	25	in	in	IN
cord-010027-r0tl01kq	1761	26	epoxy	epoxy	NN
cord-010027-r0tl01kq	1761	27	resin	resin	NN
cord-010027-r0tl01kq	1761	28	prior	prior	JJ
cord-010027-r0tl01kq	1761	29	viewing	view	VBG
cord-010027-r0tl01kq	1761	30	under	under	IN
cord-010027-r0tl01kq	1761	31	a	a	DT
cord-010027-r0tl01kq	1761	32	Technai	Technai	NNP
cord-010027-r0tl01kq	1761	33	12	12	CD
cord-010027-r0tl01kq	1761	34	transmission	transmission	NN
cord-010027-r0tl01kq	1761	35	electron	electron	NN
cord-010027-r0tl01kq	1761	36	microscope	microscope	NN
cord-010027-r0tl01kq	1761	37	.	.	.
cord-010027-r0tl01kq	1762	1	Glomerular	glomerular	JJ
cord-010027-r0tl01kq	1762	2	basement	basement	NN
cord-010027-r0tl01kq	1762	3	membrane	membrane	NN
cord-010027-r0tl01kq	1762	4	(	(	-LRB-
cord-010027-r0tl01kq	1762	5	GBM	GBM	NNP
cord-010027-r0tl01kq	1762	6	)	)	-RRB-
cord-010027-r0tl01kq	1762	7	thickness	thickness	NN
cord-010027-r0tl01kq	1762	8	,	,	,
cord-010027-r0tl01kq	1762	9	podocyte	podocyte	NNP
cord-010027-r0tl01kq	1762	10	foot	foot	NN
cord-010027-r0tl01kq	1762	11	process	process	NN
cord-010027-r0tl01kq	1762	12	diameter	diameter	NN
cord-010027-r0tl01kq	1762	13	(	(	-LRB-
cord-010027-r0tl01kq	1762	14	PFPD	PFPD	NNP
cord-010027-r0tl01kq	1762	15	)	)	-RRB-
cord-010027-r0tl01kq	1762	16	and	and	CC
cord-010027-r0tl01kq	1762	17	podocyte	podocyte	NNP
cord-010027-r0tl01kq	1762	18	foot	foot	NN
cord-010027-r0tl01kq	1762	19	process	process	NN
cord-010027-r0tl01kq	1762	20	frequency	frequency	NN
cord-010027-r0tl01kq	1762	21	(	(	-LRB-
cord-010027-r0tl01kq	1762	22	PFPF	PFPF	NNP
cord-010027-r0tl01kq	1762	23	)	)	-RRB-
cord-010027-r0tl01kq	1763	1	per	per	IN
cord-010027-r0tl01kq	1763	2	unit	unit	NN
cord-010027-r0tl01kq	1763	3	length	length	NN
cord-010027-r0tl01kq	1763	4	of	of	IN
cord-010027-r0tl01kq	1763	5	GBM	GBM	NNP
cord-010027-r0tl01kq	1763	6	were	be	VBD
cord-010027-r0tl01kq	1763	7	determined	determine	VBN
cord-010027-r0tl01kq	1763	8	for	for	IN
cord-010027-r0tl01kq	1763	9	each	each	DT
cord-010027-r0tl01kq	1763	10	group	group	NN
cord-010027-r0tl01kq	1763	11	(	(	-LRB-
cord-010027-r0tl01kq	1763	12	Sham	Sham	NNP
cord-010027-r0tl01kq	1763	13	and	and	CC
cord-010027-r0tl01kq	1763	14	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1763	15	operated	operate	VBD
cord-010027-r0tl01kq	1763	16	ZDF	ZDF	NNP
cord-010027-r0tl01kq	1763	17	fa	fa	NNP
cord-010027-r0tl01kq	1763	18	/	/	SYM
cord-010027-r0tl01kq	1763	19	fa	fa	NN
cord-010027-r0tl01kq	1763	20	diabetic	diabetic	JJ
cord-010027-r0tl01kq	1763	21	animals	animal	NNS
cord-010027-r0tl01kq	1763	22	vs	vs	IN
cord-010027-r0tl01kq	1763	23	non	non	JJ
cord-010027-r0tl01kq	1763	24	-	-	JJ
cord-010027-r0tl01kq	1763	25	operated	operated	JJ
cord-010027-r0tl01kq	1763	26	non	non	JJ
cord-010027-r0tl01kq	1763	27	-	-	JJ
cord-010027-r0tl01kq	1763	28	diabetic	diabetic	JJ
cord-010027-r0tl01kq	1763	29	ZDF	ZDF	NNP
cord-010027-r0tl01kq	1763	30	fa/+	fa/+	IN
cord-010027-r0tl01kq	1763	31	lean	lean	JJ
cord-010027-r0tl01kq	1763	32	controls	control	NNS
cord-010027-r0tl01kq	1763	33	)	)	-RRB-
cord-010027-r0tl01kq	1763	34	.	.	.
cord-010027-r0tl01kq	1764	1	Statistical	statistical	JJ
cord-010027-r0tl01kq	1764	2	analysis	analysis	NN
cord-010027-r0tl01kq	1764	3	was	be	VBD
cord-010027-r0tl01kq	1764	4	performed	perform	VBN
cord-010027-r0tl01kq	1764	5	using	use	VBG
cord-010027-r0tl01kq	1764	6	a	a	DT
cord-010027-r0tl01kq	1764	7	Mann	Mann	NNP
cord-010027-r0tl01kq	1764	8	Whitney	Whitney	NNP
cord-010027-r0tl01kq	1764	9	U	U	NNP
cord-010027-r0tl01kq	1764	10	test	test	NN
cord-010027-r0tl01kq	1764	11	and	and	CC
cord-010027-r0tl01kq	1764	12	an	an	DT
cord-010027-r0tl01kq	1764	13	unpaired	unpaired	JJ
cord-010027-r0tl01kq	1764	14	t	t	NN
cord-010027-r0tl01kq	1764	15	-	-	HYPH
cord-010027-r0tl01kq	1764	16	test	test	NN
cord-010027-r0tl01kq	1764	17	where	where	WRB
cord-010027-r0tl01kq	1764	18	appropriate	appropriate	JJ
cord-010027-r0tl01kq	1764	19	.	.	.
cord-010027-r0tl01kq	1765	1	Summary	summary	NN
cord-010027-r0tl01kq	1765	2	of	of	IN
cord-010027-r0tl01kq	1765	3	Results	result	NNS
cord-010027-r0tl01kq	1765	4	:	:	:
cord-010027-r0tl01kq	1765	5	Selected	select	VBN
cord-010027-r0tl01kq	1765	6	TEM	tem	NN
cord-010027-r0tl01kq	1765	7	parameters	parameter	NNS
cord-010027-r0tl01kq	1765	8	(	(	-LRB-
cord-010027-r0tl01kq	1765	9	GBM	GBM	NNP
cord-010027-r0tl01kq	1765	10	thickness	thickness	NN
cord-010027-r0tl01kq	1765	11	,	,	,
cord-010027-r0tl01kq	1765	12	PFPD	PFPD	NNP
cord-010027-r0tl01kq	1765	13	and	and	CC
cord-010027-r0tl01kq	1765	14	PFPF	PFPF	NNP
cord-010027-r0tl01kq	1765	15	)	)	-RRB-
cord-010027-r0tl01kq	1765	16	demonstrated	demonstrate	VBD
cord-010027-r0tl01kq	1765	17	significant	significant	JJ
cord-010027-r0tl01kq	1765	18	differences	difference	NNS
cord-010027-r0tl01kq	1765	19	between	between	IN
cord-010027-r0tl01kq	1765	20	specified	specify	VBN
cord-010027-r0tl01kq	1765	21	Sham	Sham	NNP
cord-010027-r0tl01kq	1765	22	-	-	HYPH
cord-010027-r0tl01kq	1765	23	operated	operate	VBN
cord-010027-r0tl01kq	1765	24	ZDF	ZDF	NNP
cord-010027-r0tl01kq	1765	25	fa	fa	NNP
cord-010027-r0tl01kq	1765	26	/	/	SYM
cord-010027-r0tl01kq	1765	27	fa	fa	FW
cord-010027-r0tl01kq	1765	28	vs	vs	FW
cord-010027-r0tl01kq	1765	29	fa/+	fa/+	NN
cord-010027-r0tl01kq	1765	30	samples	sample	NNS
cord-010027-r0tl01kq	1765	31	,	,	,
cord-010027-r0tl01kq	1765	32	p=0.017	p=0.017	NNS
cord-010027-r0tl01kq	1765	33	.	.	.
cord-010027-r0tl01kq	1766	1	Analysis	analysis	NN
cord-010027-r0tl01kq	1766	2	of	of	IN
cord-010027-r0tl01kq	1766	3	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1766	4	interventional	interventional	JJ
cord-010027-r0tl01kq	1766	5	study	study	NN
cord-010027-r0tl01kq	1766	6	samples	sample	NNS
cord-010027-r0tl01kq	1766	7	still	still	RB
cord-010027-r0tl01kq	1766	8	in	in	IN
cord-010027-r0tl01kq	1766	9	progress	progress	NN
cord-010027-r0tl01kq	1766	10	.	.	.
cord-010027-r0tl01kq	1767	1	Early	early	JJ
cord-010027-r0tl01kq	1767	2	post	post	JJ
cord-010027-r0tl01kq	1767	3	-	-	JJ
cord-010027-r0tl01kq	1767	4	operative	operative	JJ
cord-010027-r0tl01kq	1767	5	glucose	glucose	NN
cord-010027-r0tl01kq	1767	6	measurements	measurement	NNS
cord-010027-r0tl01kq	1767	7	showed	show	VBD
cord-010027-r0tl01kq	1767	8	a	a	DT
cord-010027-r0tl01kq	1767	9	significant	significant	JJ
cord-010027-r0tl01kq	1767	10	improvement	improvement	NN
cord-010027-r0tl01kq	1767	11	in	in	IN
cord-010027-r0tl01kq	1767	12	glucose	glucose	NN
cord-010027-r0tl01kq	1767	13	homeostasis	homeostasis	NN
cord-010027-r0tl01kq	1767	14	in	in	IN
cord-010027-r0tl01kq	1767	15	the	the	DT
cord-010027-r0tl01kq	1767	16	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1767	17	group	group	NN
cord-010027-r0tl01kq	1767	18	(	(	-LRB-
cord-010027-r0tl01kq	1767	19	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1767	20	vs	vs	IN
cord-010027-r0tl01kq	1767	21	SHAM	SHAM	NNP
cord-010027-r0tl01kq	1767	22	,	,	,
cord-010027-r0tl01kq	1767	23	P=0.0001	P=0.0001	NNP
cord-010027-r0tl01kq	1767	24	)	)	-RRB-
cord-010027-r0tl01kq	1767	25	occurring	occur	VBG
cord-010027-r0tl01kq	1767	26	independently	independently	RB
cord-010027-r0tl01kq	1767	27	of	of	IN
cord-010027-r0tl01kq	1767	28	weight	weight	NN
cord-010027-r0tl01kq	1767	29	loss	loss	NN
cord-010027-r0tl01kq	1767	30	.	.	.
cord-010027-r0tl01kq	1768	1	Urinary	urinary	JJ
cord-010027-r0tl01kq	1768	2	albumin	albumin	NN
cord-010027-r0tl01kq	1768	3	:	:	:
cord-010027-r0tl01kq	1769	1	creatinine	creatinine	NN
cord-010027-r0tl01kq	1769	2	ratios	ratio	NNS
cord-010027-r0tl01kq	1769	3	were	be	VBD
cord-010027-r0tl01kq	1769	4	lower	low	JJR
cord-010027-r0tl01kq	1769	5	in	in	IN
cord-010027-r0tl01kq	1769	6	the	the	DT
cord-010027-r0tl01kq	1769	7	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1769	8	group	group	NN
cord-010027-r0tl01kq	1769	9	vs	vs	IN
cord-010027-r0tl01kq	1770	1	Sham	Sham	NNP
cord-010027-r0tl01kq	1770	2	operated	operate	VBD
cord-010027-r0tl01kq	1770	3	positive	positive	JJ
cord-010027-r0tl01kq	1770	4	controls	control	NNS
cord-010027-r0tl01kq	1770	5	(	(	-LRB-
cord-010027-r0tl01kq	1770	6	P=0.0079	P=0.0079	NNP
cord-010027-r0tl01kq	1770	7	)	)	-RRB-
cord-010027-r0tl01kq	1770	8	and	and	CC
cord-010027-r0tl01kq	1770	9	were	be	VBD
cord-010027-r0tl01kq	1770	10	comparable	comparable	JJ
cord-010027-r0tl01kq	1770	11	with	with	IN
cord-010027-r0tl01kq	1770	12	age	age	NN
cord-010027-r0tl01kq	1770	13	-	-	HYPH
cord-010027-r0tl01kq	1770	14	matched	match	VBN
cord-010027-r0tl01kq	1770	15	lean	lean	JJ
cord-010027-r0tl01kq	1770	16	control	control	NN
cord-010027-r0tl01kq	1770	17	fa/+	fa/+	NN
cord-010027-r0tl01kq	1770	18	samples	sample	NNS
cord-010027-r0tl01kq	1770	19	.	.	.
cord-010027-r0tl01kq	1771	1	Conclusions	conclusion	NNS
cord-010027-r0tl01kq	1771	2	:	:	:
cord-010027-r0tl01kq	1772	1	Preliminary	preliminary	JJ
cord-010027-r0tl01kq	1772	2	findings	finding	NNS
cord-010027-r0tl01kq	1772	3	support	support	VBP
cord-010027-r0tl01kq	1772	4	a	a	DT
cord-010027-r0tl01kq	1772	5	beneficial	beneficial	JJ
cord-010027-r0tl01kq	1772	6	role	role	NN
cord-010027-r0tl01kq	1772	7	for	for	IN
cord-010027-r0tl01kq	1772	8	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1772	9	in	in	IN
cord-010027-r0tl01kq	1772	10	an	an	DT
cord-010027-r0tl01kq	1772	11	animal	animal	NN
cord-010027-r0tl01kq	1772	12	model	model	NN
cord-010027-r0tl01kq	1772	13	of	of	IN
cord-010027-r0tl01kq	1772	14	'	'	``
cord-010027-r0tl01kq	1772	15	Diabesity	Diabesity	NNP
cord-010027-r0tl01kq	1772	16	'	'	''
cord-010027-r0tl01kq	1772	17	.	.	.
cord-010027-r0tl01kq	1773	1	Validated	validate	VBN
cord-010027-r0tl01kq	1773	2	ultrastructural	ultrastructural	JJ
cord-010027-r0tl01kq	1773	3	parameters	parameter	NNS
cord-010027-r0tl01kq	1773	4	should	should	MD
cord-010027-r0tl01kq	1773	5	assist	assist	VB
cord-010027-r0tl01kq	1773	6	in	in	IN
cord-010027-r0tl01kq	1773	7	elucidating	elucidate	VBG
cord-010027-r0tl01kq	1773	8	changes	change	NNS
cord-010027-r0tl01kq	1773	9	in	in	IN
cord-010027-r0tl01kq	1773	10	podocyte	podocyte	NNP
cord-010027-r0tl01kq	1773	11	activation	activation	NN
cord-010027-r0tl01kq	1773	12	and	and	CC
cord-010027-r0tl01kq	1773	13	differentiation	differentiation	NN
cord-010027-r0tl01kq	1773	14	as	as	IN
cord-010027-r0tl01kq	1773	15	mediators	mediator	NNS
cord-010027-r0tl01kq	1773	16	of	of	IN
cord-010027-r0tl01kq	1773	17	the	the	DT
cord-010027-r0tl01kq	1773	18	observed	observed	JJ
cord-010027-r0tl01kq	1773	19	remission	remission	NN
cord-010027-r0tl01kq	1773	20	of	of	IN
cord-010027-r0tl01kq	1773	21	albuminuria	albuminuria	NNS
cord-010027-r0tl01kq	1773	22	following	follow	VBG
cord-010027-r0tl01kq	1773	23	RYGB	RYGB	NNP
cord-010027-r0tl01kq	1773	24	surgery	surgery	NN
cord-010027-r0tl01kq	1773	25	.	.	.
cord-010027-r0tl01kq	1774	1	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	1774	2	University	University	NNP
cord-010027-r0tl01kq	1774	3	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1774	4	,	,	,
cord-010027-r0tl01kq	1774	5	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	1774	6	,	,	,
cord-010027-r0tl01kq	1774	7	UK	UK	NNP
cord-010027-r0tl01kq	1774	8	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1774	9	naevus	naevus	NN
cord-010027-r0tl01kq	1774	10	is	be	VBZ
cord-010027-r0tl01kq	1774	11	a	a	DT
cord-010027-r0tl01kq	1774	12	benign	benign	JJ
cord-010027-r0tl01kq	1774	13	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	1774	14	lesion	lesion	NN
cord-010027-r0tl01kq	1774	15	that	that	WDT
cord-010027-r0tl01kq	1774	16	shares	share	VBZ
cord-010027-r0tl01kq	1774	17	many	many	JJ
cord-010027-r0tl01kq	1774	18	histological	histological	JJ
cord-010027-r0tl01kq	1774	19	features	feature	NNS
cord-010027-r0tl01kq	1774	20	with	with	IN
cord-010027-r0tl01kq	1774	21	malignant	malignant	JJ
cord-010027-r0tl01kq	1774	22	melanoma	melanoma	NN
cord-010027-r0tl01kq	1774	23	.	.	.
cord-010027-r0tl01kq	1775	1	Although	although	IN
cord-010027-r0tl01kq	1775	2	the	the	DT
cord-010027-r0tl01kq	1775	3	morphological	morphological	JJ
cord-010027-r0tl01kq	1775	4	criteria	criterion	NNS
cord-010027-r0tl01kq	1775	5	differentiating	differentiate	VBG
cord-010027-r0tl01kq	1775	6	the	the	DT
cord-010027-r0tl01kq	1775	7	two	two	CD
cord-010027-r0tl01kq	1775	8	entities	entity	NNS
cord-010027-r0tl01kq	1775	9	are	be	VBP
cord-010027-r0tl01kq	1775	10	well	well	RB
cord-010027-r0tl01kq	1775	11	established	establish	VBN
cord-010027-r0tl01kq	1775	12	however	however	RB
cord-010027-r0tl01kq	1775	13	,	,	,
cord-010027-r0tl01kq	1775	14	some	some	DT
cord-010027-r0tl01kq	1775	15	cases	case	NNS
cord-010027-r0tl01kq	1775	16	can	can	MD
cord-010027-r0tl01kq	1775	17	be	be	VB
cord-010027-r0tl01kq	1775	18	challenging	challenging	JJ
cord-010027-r0tl01kq	1775	19	.	.	.
cord-010027-r0tl01kq	1776	1	Many	many	JJ
cord-010027-r0tl01kq	1776	2	isolated	isolate	VBN
cord-010027-r0tl01kq	1776	3	markers	marker	NNS
cord-010027-r0tl01kq	1776	4	have	have	VBP
cord-010027-r0tl01kq	1776	5	been	be	VBN
cord-010027-r0tl01kq	1776	6	proposed	propose	VBN
cord-010027-r0tl01kq	1776	7	to	to	TO
cord-010027-r0tl01kq	1776	8	help	help	VB
cord-010027-r0tl01kq	1776	9	in	in	IN
cord-010027-r0tl01kq	1776	10	differentiating	differentiate	VBG
cord-010027-r0tl01kq	1776	11	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1776	12	naevus	naevus	NN
cord-010027-r0tl01kq	1776	13	from	from	IN
cord-010027-r0tl01kq	1776	14	melanoma	melanoma	NN
cord-010027-r0tl01kq	1776	15	,	,	,
cord-010027-r0tl01kq	1776	16	albeit	albeit	IN
cord-010027-r0tl01kq	1776	17	none	none	NN
cord-010027-r0tl01kq	1776	18	has	have	VBZ
cord-010027-r0tl01kq	1776	19	been	be	VBN
cord-010027-r0tl01kq	1776	20	shown	show	VBN
cord-010027-r0tl01kq	1776	21	to	to	TO
cord-010027-r0tl01kq	1776	22	be	be	VB
cord-010027-r0tl01kq	1776	23	definitive	definitive	JJ
cord-010027-r0tl01kq	1776	24	.	.	.
cord-010027-r0tl01kq	1777	1	Aim	aim	VB
cord-010027-r0tl01kq	1777	2	:	:	:
cord-010027-r0tl01kq	1778	1	This	this	DT
cord-010027-r0tl01kq	1778	2	is	be	VBZ
cord-010027-r0tl01kq	1778	3	a	a	DT
cord-010027-r0tl01kq	1778	4	preliminary	preliminary	JJ
cord-010027-r0tl01kq	1778	5	study	study	NN
cord-010027-r0tl01kq	1778	6	looking	look	VBG
cord-010027-r0tl01kq	1778	7	at	at	IN
cord-010027-r0tl01kq	1778	8	the	the	DT
cord-010027-r0tl01kq	1778	9	immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	1778	10	expression	expression	NN
cord-010027-r0tl01kq	1778	11	of	of	IN
cord-010027-r0tl01kq	1778	12	3	3	CD
cord-010027-r0tl01kq	1778	13	markers	marker	NNS
cord-010027-r0tl01kq	1778	14	that	that	WDT
cord-010027-r0tl01kq	1778	15	are	be	VBP
cord-010027-r0tl01kq	1778	16	known	know	VBN
cord-010027-r0tl01kq	1778	17	to	to	TO
cord-010027-r0tl01kq	1778	18	have	have	VB
cord-010027-r0tl01kq	1778	19	important	important	JJ
cord-010027-r0tl01kq	1778	20	role	role	NN
cord-010027-r0tl01kq	1778	21	in	in	IN
cord-010027-r0tl01kq	1778	22	cell	cell	NN
cord-010027-r0tl01kq	1778	23	cycle	cycle	NN
cord-010027-r0tl01kq	1778	24	regulation	regulation	NN
cord-010027-r0tl01kq	1778	25	,	,	,
cord-010027-r0tl01kq	1778	26	proliferation	proliferation	NN
cord-010027-r0tl01kq	1778	27	and	and	CC
cord-010027-r0tl01kq	1778	28	melanocytic	melanocytic	JJ
cord-010027-r0tl01kq	1778	29	differentiation	differentiation	NN
cord-010027-r0tl01kq	1778	30	(	(	-LRB-
cord-010027-r0tl01kq	1778	31	P16	P16	NNP
cord-010027-r0tl01kq	1778	32	,	,	,
cord-010027-r0tl01kq	1778	33	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1778	34	,	,	,
cord-010027-r0tl01kq	1778	35	and	and	CC
cord-010027-r0tl01kq	1778	36	HMB45	HMB45	NNP
cord-010027-r0tl01kq	1778	37	)	)	-RRB-
cord-010027-r0tl01kq	1778	38	.	.	.
cord-010027-r0tl01kq	1779	1	The	the	DT
cord-010027-r0tl01kq	1779	2	aim	aim	NN
cord-010027-r0tl01kq	1779	3	is	be	VBZ
cord-010027-r0tl01kq	1779	4	provide	provide	JJ
cord-010027-r0tl01kq	1779	5	to	to	IN
cord-010027-r0tl01kq	1779	6	a	a	DT
cord-010027-r0tl01kq	1779	7	combination	combination	NN
cord-010027-r0tl01kq	1779	8	of	of	IN
cord-010027-r0tl01kq	1779	9	proteins	protein	NNS
cord-010027-r0tl01kq	1779	10	that	that	WDT
cord-010027-r0tl01kq	1779	11	can	can	MD
cord-010027-r0tl01kq	1779	12	help	help	VB
cord-010027-r0tl01kq	1779	13	in	in	IN
cord-010027-r0tl01kq	1779	14	differentiating	differentiate	VBG
cord-010027-r0tl01kq	1779	15	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1779	16	naevus	naevus	NN
cord-010027-r0tl01kq	1779	17	from	from	IN
cord-010027-r0tl01kq	1779	18	malignant	malignant	JJ
cord-010027-r0tl01kq	1779	19	melanoma	melanoma	NN
cord-010027-r0tl01kq	1779	20	.	.	.
cord-010027-r0tl01kq	1780	1	The	the	DT
cord-010027-r0tl01kq	1780	2	study	study	NN
cord-010027-r0tl01kq	1780	3	included	include	VBD
cord-010027-r0tl01kq	1780	4	12	12	CD
cord-010027-r0tl01kq	1780	5	cases	case	NNS
cord-010027-r0tl01kq	1780	6	of	of	IN
cord-010027-r0tl01kq	1780	7	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1780	8	naevi	naevi	NN
cord-010027-r0tl01kq	1780	9	,	,	,
cord-010027-r0tl01kq	1780	10	6	6	CD
cord-010027-r0tl01kq	1780	11	benign	benign	JJ
cord-010027-r0tl01kq	1780	12	compound	compound	NN
cord-010027-r0tl01kq	1780	13	naevi	naevus	NNS
cord-010027-r0tl01kq	1780	14	and	and	CC
cord-010027-r0tl01kq	1780	15	6	6	CD
cord-010027-r0tl01kq	1780	16	cases	case	NNS
cord-010027-r0tl01kq	1780	17	of	of	IN
cord-010027-r0tl01kq	1780	18	malignant	malignant	JJ
cord-010027-r0tl01kq	1780	19	melanoma	melanoma	NN
cord-010027-r0tl01kq	1780	20	.	.	.
cord-010027-r0tl01kq	1781	1	Immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	1781	2	expression	expression	NN
cord-010027-r0tl01kq	1781	3	of	of	IN
cord-010027-r0tl01kq	1781	4	p16	p16	NN
cord-010027-r0tl01kq	1781	5	,	,	,
cord-010027-r0tl01kq	1781	6	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1781	7	,	,	,
cord-010027-r0tl01kq	1781	8	and	and	CC
cord-010027-r0tl01kq	1781	9	HMB45	HMB45	NNP
cord-010027-r0tl01kq	1781	10	has	have	VBZ
cord-010027-r0tl01kq	1781	11	been	be	VBN
cord-010027-r0tl01kq	1781	12	accessed	access	VBN
cord-010027-r0tl01kq	1781	13	and	and	CC
cord-010027-r0tl01kq	1781	14	compared	compare	VBN
cord-010027-r0tl01kq	1781	15	with	with	IN
cord-010027-r0tl01kq	1781	16	the	the	DT
cord-010027-r0tl01kq	1781	17	morphological	morphological	JJ
cord-010027-r0tl01kq	1781	18	features	feature	NNS
cord-010027-r0tl01kq	1781	19	of	of	IN
cord-010027-r0tl01kq	1781	20	these	these	DT
cord-010027-r0tl01kq	1781	21	lesions	lesion	NNS
cord-010027-r0tl01kq	1781	22	.	.	.
cord-010027-r0tl01kq	1782	1	Results	result	NNS
cord-010027-r0tl01kq	1782	2	:	:	:
cord-010027-r0tl01kq	1783	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1783	2	is	be	VBZ
cord-010027-r0tl01kq	1783	3	noted	note	VBN
cord-010027-r0tl01kq	1783	4	the	the	DT
cord-010027-r0tl01kq	1783	5	mean	mean	NN
cord-010027-r0tl01kq	1783	6	P16	P16	NNP
cord-010027-r0tl01kq	1783	7	expression	expression	NN
cord-010027-r0tl01kq	1783	8	is	be	VBZ
cord-010027-r0tl01kq	1783	9	higher	high	JJR
cord-010027-r0tl01kq	1783	10	in	in	IN
cord-010027-r0tl01kq	1783	11	compound	compound	NN
cord-010027-r0tl01kq	1783	12	and	and	CC
cord-010027-r0tl01kq	1783	13	spitz	spitz	NNP
cord-010027-r0tl01kq	1783	14	naevi	naevi	NNP
cord-010027-r0tl01kq	1783	15	than	than	IN
cord-010027-r0tl01kq	1783	16	melanoma	melanoma	NN
cord-010027-r0tl01kq	1783	17	(	(	-LRB-
cord-010027-r0tl01kq	1783	18	83	83	CD
cord-010027-r0tl01kq	1783	19	,	,	,
cord-010027-r0tl01kq	1783	20	91	91	CD
cord-010027-r0tl01kq	1783	21	,	,	,
cord-010027-r0tl01kq	1783	22	and	and	CC
cord-010027-r0tl01kq	1783	23	36	36	CD
cord-010027-r0tl01kq	1783	24	respectively	respectively	RB
cord-010027-r0tl01kq	1783	25	)	)	-RRB-
cord-010027-r0tl01kq	1783	26	.	.	.
cord-010027-r0tl01kq	1784	1	Proliferation	proliferation	NN
cord-010027-r0tl01kq	1784	2	activity	activity	NN
cord-010027-r0tl01kq	1784	3	as	as	IN
cord-010027-r0tl01kq	1784	4	measured	measure	VBN
cord-010027-r0tl01kq	1784	5	by	by	IN
cord-010027-r0tl01kq	1784	6	KI67	KI67	NNP
cord-010027-r0tl01kq	1784	7	index	index	NN
cord-010027-r0tl01kq	1784	8	is	be	VBZ
cord-010027-r0tl01kq	1784	9	higher	high	JJR
cord-010027-r0tl01kq	1784	10	in	in	IN
cord-010027-r0tl01kq	1784	11	melanoma	melanoma	NN
cord-010027-r0tl01kq	1784	12	in	in	IN
cord-010027-r0tl01kq	1784	13	comparison	comparison	NN
cord-010027-r0tl01kq	1784	14	with	with	IN
cord-010027-r0tl01kq	1784	15	compound	compound	NNP
cord-010027-r0tl01kq	1784	16	and	and	CC
cord-010027-r0tl01kq	1784	17	spitz	spitz	NNP
cord-010027-r0tl01kq	1784	18	naevi	naevi	NNP
cord-010027-r0tl01kq	1784	19	(	(	-LRB-
cord-010027-r0tl01kq	1784	20	30.8	30.8	CD
cord-010027-r0tl01kq	1784	21	,	,	,
cord-010027-r0tl01kq	1784	22	2.8	2.8	CD
cord-010027-r0tl01kq	1784	23	,	,	,
cord-010027-r0tl01kq	1784	24	and	and	CC
cord-010027-r0tl01kq	1784	25	1.6	1.6	CD
cord-010027-r0tl01kq	1784	26	respectively	respectively	RB
cord-010027-r0tl01kq	1784	27	)	)	-RRB-
cord-010027-r0tl01kq	1784	28	.	.	.
cord-010027-r0tl01kq	1785	1	HMB45	HMB45	NNP
cord-010027-r0tl01kq	1785	2	shows	show	VBZ
cord-010027-r0tl01kq	1785	3	only	only	RB
cord-010027-r0tl01kq	1785	4	junctional	junctional	JJ
cord-010027-r0tl01kq	1785	5	positivity	positivity	NN
cord-010027-r0tl01kq	1785	6	in	in	IN
cord-010027-r0tl01kq	1785	7	9	9	CD
cord-010027-r0tl01kq	1785	8	out	out	IN
cord-010027-r0tl01kq	1785	9	of	of	IN
cord-010027-r0tl01kq	1785	10	11	11	CD
cord-010027-r0tl01kq	1785	11	cases	case	NNS
cord-010027-r0tl01kq	1785	12	of	of	IN
cord-010027-r0tl01kq	1785	13	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1785	14	naevi	naevus	NNS
cord-010027-r0tl01kq	1785	15	while	while	IN
cord-010027-r0tl01kq	1785	16	in	in	IN
cord-010027-r0tl01kq	1785	17	the	the	DT
cord-010027-r0tl01kq	1785	18	other	other	JJ
cord-010027-r0tl01kq	1785	19	two	two	CD
cord-010027-r0tl01kq	1785	20	it	-PRON-	PRP
cord-010027-r0tl01kq	1785	21	shows	show	VBZ
cord-010027-r0tl01kq	1785	22	week	week	NN
cord-010027-r0tl01kq	1785	23	dermal	dermal	JJ
cord-010027-r0tl01kq	1785	24	component	component	NN
cord-010027-r0tl01kq	1785	25	.	.	.
cord-010027-r0tl01kq	1786	1	HMB45	HMB45	NNP
cord-010027-r0tl01kq	1786	2	is	be	VBZ
cord-010027-r0tl01kq	1786	3	constantly	constantly	RB
cord-010027-r0tl01kq	1786	4	positive	positive	JJ
cord-010027-r0tl01kq	1786	5	at	at	IN
cord-010027-r0tl01kq	1786	6	the	the	DT
cord-010027-r0tl01kq	1786	7	deep	deep	JJ
cord-010027-r0tl01kq	1786	8	dermal	dermal	JJ
cord-010027-r0tl01kq	1786	9	component	component	NN
cord-010027-r0tl01kq	1786	10	of	of	IN
cord-010027-r0tl01kq	1786	11	melanoma	melanoma	NN
cord-010027-r0tl01kq	1786	12	,	,	,
cord-010027-r0tl01kq	1786	13	albeit	albeit	IN
cord-010027-r0tl01kq	1786	14	the	the	DT
cord-010027-r0tl01kq	1786	15	staining	staining	NN
cord-010027-r0tl01kq	1786	16	intensity	intensity	NN
cord-010027-r0tl01kq	1786	17	is	be	VBZ
cord-010027-r0tl01kq	1786	18	variable	variable	JJ
cord-010027-r0tl01kq	1786	19	.	.	.
cord-010027-r0tl01kq	1787	1	The	the	DT
cord-010027-r0tl01kq	1787	2	immunoprofile	immunoprofile	NN
cord-010027-r0tl01kq	1787	3	of	of	IN
cord-010027-r0tl01kq	1787	4	Spitz	Spitz	NNP
cord-010027-r0tl01kq	1787	5	naevus	naevus	NN
cord-010027-r0tl01kq	1787	6	is	be	VBZ
cord-010027-r0tl01kq	1787	7	different	different	JJ
cord-010027-r0tl01kq	1787	8	from	from	IN
cord-010027-r0tl01kq	1787	9	that	that	DT
cord-010027-r0tl01kq	1787	10	of	of	IN
cord-010027-r0tl01kq	1787	11	a	a	DT
cord-010027-r0tl01kq	1787	12	malignant	malignant	JJ
cord-010027-r0tl01kq	1787	13	melanoma	melanoma	NN
cord-010027-r0tl01kq	1787	14	.	.	.
cord-010027-r0tl01kq	1788	1	A	a	DT
cord-010027-r0tl01kq	1788	2	combination	combination	NN
cord-010027-r0tl01kq	1788	3	of	of	IN
cord-010027-r0tl01kq	1788	4	biological	biological	JJ
cord-010027-r0tl01kq	1788	5	markers	marker	NNS
cord-010027-r0tl01kq	1788	6	as	as	IN
cord-010027-r0tl01kq	1788	7	(	(	-LRB-
cord-010027-r0tl01kq	1788	8	p16	p16	NN
cord-010027-r0tl01kq	1788	9	,	,	,
cord-010027-r0tl01kq	1788	10	Ki67	Ki67	NNP
cord-010027-r0tl01kq	1788	11	,	,	,
cord-010027-r0tl01kq	1788	12	and	and	CC
cord-010027-r0tl01kq	1788	13	HMB45	HMB45	NNP
cord-010027-r0tl01kq	1788	14	)	)	-RRB-
cord-010027-r0tl01kq	1788	15	,	,	,
cord-010027-r0tl01kq	1788	16	can	can	MD
cord-010027-r0tl01kq	1788	17	provide	provide	VB
cord-010027-r0tl01kq	1788	18	a	a	DT
cord-010027-r0tl01kq	1788	19	potential	potential	JJ
cord-010027-r0tl01kq	1788	20	tool	tool	NN
cord-010027-r0tl01kq	1788	21	to	to	TO
cord-010027-r0tl01kq	1788	22	differentiate	differentiate	VB
cord-010027-r0tl01kq	1788	23	between	between	IN
cord-010027-r0tl01kq	1788	24	the	the	DT
cord-010027-r0tl01kq	1788	25	two	two	CD
cord-010027-r0tl01kq	1788	26	entities	entity	NNS
cord-010027-r0tl01kq	1788	27	.	.	.
cord-010027-r0tl01kq	1789	1	Nevertheless	nevertheless	RB
cord-010027-r0tl01kq	1789	2	,	,	,
cord-010027-r0tl01kq	1789	3	expanding	expand	VBG
cord-010027-r0tl01kq	1789	4	the	the	DT
cord-010027-r0tl01kq	1789	5	biomarker	biomarker	NN
cord-010027-r0tl01kq	1789	6	repertoire	repertoire	NN
cord-010027-r0tl01kq	1789	7	on	on	IN
cord-010027-r0tl01kq	1789	8	a	a	DT
cord-010027-r0tl01kq	1789	9	large	large	JJ
cord-010027-r0tl01kq	1789	10	number	number	NN
cord-010027-r0tl01kq	1789	11	of	of	IN
cord-010027-r0tl01kq	1789	12	cases	case	NNS
cord-010027-r0tl01kq	1789	13	is	be	VBZ
cord-010027-r0tl01kq	1789	14	necessary	necessary	JJ
cord-010027-r0tl01kq	1789	15	to	to	TO
cord-010027-r0tl01kq	1789	16	further	further	RB
cord-010027-r0tl01kq	1789	17	establish	establish	VB
cord-010027-r0tl01kq	1789	18	a	a	DT
cord-010027-r0tl01kq	1789	19	reliable	reliable	JJ
cord-010027-r0tl01kq	1789	20	panel	panel	NN
cord-010027-r0tl01kq	1789	21	to	to	TO
cord-010027-r0tl01kq	1789	22	differentiate	differentiate	VB
cord-010027-r0tl01kq	1789	23	among	among	IN
cord-010027-r0tl01kq	1789	24	difficult	difficult	JJ
cord-010027-r0tl01kq	1789	25	cases	case	NNS
cord-010027-r0tl01kq	1789	26	.	.	.
cord-010027-r0tl01kq	1790	1	Direct	direct	JJ
cord-010027-r0tl01kq	1790	2	Immunofluorescence	Immunofluorescence	NNP
cord-010027-r0tl01kq	1790	3	in	in	IN
cord-010027-r0tl01kq	1790	4	a	a	DT
cord-010027-r0tl01kq	1790	5	Tertiary	Tertiary	NNP
cord-010027-r0tl01kq	1790	6	Referral	Referral	NNP
cord-010027-r0tl01kq	1790	7	Centre	Centre	NNP
cord-010027-r0tl01kq	1790	8	:	:	:
cord-010027-r0tl01kq	1791	1	An	an	DT
cord-010027-r0tl01kq	1791	2	Audit	Audit	NNP
cord-010027-r0tl01kq	1791	3	of	of	IN
cord-010027-r0tl01kq	1791	4	Local	Local	NNP
cord-010027-r0tl01kq	1791	5	Guidelines	Guidelines	NNPS
cord-010027-r0tl01kq	1791	6	and	and	CC
cord-010027-r0tl01kq	1791	7	Usage	Usage	NNP
cord-010027-r0tl01kq	1791	8	P	P	NNP
cord-010027-r0tl01kq	1791	9	LJ	LJ	NNP
cord-010027-r0tl01kq	1791	10	Lumsden	Lumsden	NNP
cord-010027-r0tl01kq	1791	11	;	;	:
cord-010027-r0tl01kq	1791	12	L	L	NNP
cord-010027-r0tl01kq	1791	13	Motta	Motta	NNP
cord-010027-r0tl01kq	1791	14	;	;	:
cord-010027-r0tl01kq	1791	15	R	R	NNP
cord-010027-r0tl01kq	1791	16	Green	Green	NNP
cord-010027-r0tl01kq	1791	17	Salford	Salford	NNP
cord-010027-r0tl01kq	1791	18	Royal	Royal	NNP
cord-010027-r0tl01kq	1791	19	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1791	20	,	,	,
cord-010027-r0tl01kq	1791	21	Salford	Salford	NNP
cord-010027-r0tl01kq	1791	22	,	,	,
cord-010027-r0tl01kq	1791	23	UK	UK	NNP
cord-010027-r0tl01kq	1791	24	Direct	direct	JJ
cord-010027-r0tl01kq	1791	25	immunofluorescence	immunofluorescence	NN
cord-010027-r0tl01kq	1791	26	(	(	-LRB-
cord-010027-r0tl01kq	1791	27	DIF	DIF	NNP
cord-010027-r0tl01kq	1791	28	)	)	-RRB-
cord-010027-r0tl01kq	1791	29	forms	form	VBZ
cord-010027-r0tl01kq	1791	30	an	an	DT
cord-010027-r0tl01kq	1791	31	important	important	JJ
cord-010027-r0tl01kq	1791	32	and	and	CC
cord-010027-r0tl01kq	1791	33	costly	costly	JJ
cord-010027-r0tl01kq	1791	34	adjunct	adjunct	NN
cord-010027-r0tl01kq	1791	35	to	to	IN
cord-010027-r0tl01kq	1791	36	conventional	conventional	JJ
cord-010027-r0tl01kq	1791	37	haematoxylin	haematoxylin	NN
cord-010027-r0tl01kq	1791	38	and	and	CC
cord-010027-r0tl01kq	1791	39	eosin	eosin	NNP
cord-010027-r0tl01kq	1791	40	(	(	-LRB-
cord-010027-r0tl01kq	1791	41	H&E	H&E	NNP
cord-010027-r0tl01kq	1791	42	)	)	-RRB-
cord-010027-r0tl01kq	1791	43	histology	histology	NN
cord-010027-r0tl01kq	1791	44	in	in	IN
cord-010027-r0tl01kq	1791	45	dermatopathology	dermatopathology	NN
cord-010027-r0tl01kq	1791	46	,	,	,
cord-010027-r0tl01kq	1791	47	particularly	particularly	RB
cord-010027-r0tl01kq	1791	48	in	in	IN
cord-010027-r0tl01kq	1791	49	bullous	bullous	JJ
cord-010027-r0tl01kq	1791	50	diseases	disease	NNS
cord-010027-r0tl01kq	1791	51	and	and	CC
cord-010027-r0tl01kq	1791	52	other	other	JJ
cord-010027-r0tl01kq	1791	53	immune	immune	NN
cord-010027-r0tl01kq	1791	54	-	-	HYPH
cord-010027-r0tl01kq	1791	55	mediated	mediate	VBN
cord-010027-r0tl01kq	1791	56	diseases	disease	NNS
cord-010027-r0tl01kq	1791	57	.	.	.
cord-010027-r0tl01kq	1792	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1792	2	aim	aim	VBP
cord-010027-r0tl01kq	1792	3	to	to	TO
cord-010027-r0tl01kq	1792	4	assess	assess	VB
cord-010027-r0tl01kq	1792	5	the	the	DT
cord-010027-r0tl01kq	1792	6	usage	usage	NN
cord-010027-r0tl01kq	1792	7	and	and	CC
cord-010027-r0tl01kq	1792	8	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1792	9	yield	yield	NN
cord-010027-r0tl01kq	1792	10	of	of	IN
cord-010027-r0tl01kq	1792	11	DIF	DIF	NNP
cord-010027-r0tl01kq	1792	12	in	in	IN
cord-010027-r0tl01kq	1792	13	our	-PRON-	PRP$
cord-010027-r0tl01kq	1792	14	dermatopathology	dermatopathology	NN
cord-010027-r0tl01kq	1792	15	department	department	NN
cord-010027-r0tl01kq	1792	16	.	.	.
cord-010027-r0tl01kq	1793	1	134	134	CD
cord-010027-r0tl01kq	1793	2	requests	request	NNS
cord-010027-r0tl01kq	1793	3	for	for	IN
cord-010027-r0tl01kq	1793	4	DIF	DIF	NNP
cord-010027-r0tl01kq	1793	5	on	on	IN
cord-010027-r0tl01kq	1793	6	skin	skin	NN
cord-010027-r0tl01kq	1793	7	biopsies	biopsy	NNS
cord-010027-r0tl01kq	1793	8	received	receive	VBN
cord-010027-r0tl01kq	1793	9	over	over	IN
cord-010027-r0tl01kq	1793	10	a	a	DT
cord-010027-r0tl01kq	1793	11	5	5	CD
cord-010027-r0tl01kq	1793	12	month	month	NN
cord-010027-r0tl01kq	1793	13	period	period	NN
cord-010027-r0tl01kq	1793	14	met	meet	VBD
cord-010027-r0tl01kq	1793	15	the	the	DT
cord-010027-r0tl01kq	1793	16	inclusion	inclusion	NN
cord-010027-r0tl01kq	1793	17	criteria	criterion	NNS
cord-010027-r0tl01kq	1793	18	.	.	.
cord-010027-r0tl01kq	1794	1	Each	each	DT
cord-010027-r0tl01kq	1794	2	individual	individual	JJ
cord-010027-r0tl01kq	1794	3	report	report	NN
cord-010027-r0tl01kq	1794	4	was	be	VBD
cord-010027-r0tl01kq	1794	5	assessed	assess	VBN
cord-010027-r0tl01kq	1794	6	with	with	IN
cord-010027-r0tl01kq	1794	7	regard	regard	NN
cord-010027-r0tl01kq	1794	8	to	to	IN
cord-010027-r0tl01kq	1794	9	the	the	DT
cord-010027-r0tl01kq	1794	10	indication	indication	NN
cord-010027-r0tl01kq	1794	11	for	for	IN
cord-010027-r0tl01kq	1794	12	DIF	DIF	NNP
cord-010027-r0tl01kq	1794	13	,	,	,
cord-010027-r0tl01kq	1794	14	whether	whether	IN
cord-010027-r0tl01kq	1794	15	DIF	DIF	NNP
cord-010027-r0tl01kq	1794	16	was	be	VBD
cord-010027-r0tl01kq	1794	17	deemed	deem	VBN
cord-010027-r0tl01kq	1794	18	to	to	TO
cord-010027-r0tl01kq	1794	19	be	be	VB
cord-010027-r0tl01kq	1794	20	indicated	indicate	VBN
cord-010027-r0tl01kq	1794	21	or	or	CC
cord-010027-r0tl01kq	1794	22	not	not	RB
cord-010027-r0tl01kq	1794	23	indicated	indicate	VBN
cord-010027-r0tl01kq	1794	24	on	on	IN
cord-010027-r0tl01kq	1794	25	assessment	assessment	NN
cord-010027-r0tl01kq	1794	26	of	of	IN
cord-010027-r0tl01kq	1794	27	the	the	DT
cord-010027-r0tl01kq	1794	28	clinical	clinical	JJ
cord-010027-r0tl01kq	1794	29	history	history	NN
cord-010027-r0tl01kq	1794	30	supplied	supply	VBN
cord-010027-r0tl01kq	1794	31	on	on	IN
cord-010027-r0tl01kq	1794	32	the	the	DT
cord-010027-r0tl01kq	1794	33	request	request	NN
cord-010027-r0tl01kq	1794	34	card	card	NN
cord-010027-r0tl01kq	1794	35	,	,	,
cord-010027-r0tl01kq	1794	36	the	the	DT
cord-010027-r0tl01kq	1794	37	results	result	NNS
cord-010027-r0tl01kq	1794	38	of	of	IN
cord-010027-r0tl01kq	1794	39	DIF	DIF	NNP
cord-010027-r0tl01kq	1794	40	and	and	CC
cord-010027-r0tl01kq	1794	41	whether	whether	IN
cord-010027-r0tl01kq	1794	42	DIF	DIF	NNP
cord-010027-r0tl01kq	1794	43	was	be	VBD
cord-010027-r0tl01kq	1794	44	contributory	contributory	JJ
cord-010027-r0tl01kq	1794	45	to	to	IN
cord-010027-r0tl01kq	1794	46	the	the	DT
cord-010027-r0tl01kq	1794	47	final	final	JJ
cord-010027-r0tl01kq	1794	48	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1794	49	.	.	.
cord-010027-r0tl01kq	1795	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1795	2	also	also	RB
cord-010027-r0tl01kq	1795	3	collected	collect	VBD
cord-010027-r0tl01kq	1795	4	data	datum	NNS
cord-010027-r0tl01kq	1795	5	on	on	IN
cord-010027-r0tl01kq	1795	6	the	the	DT
cord-010027-r0tl01kq	1795	7	usage	usage	NN
cord-010027-r0tl01kq	1795	8	of	of	IN
cord-010027-r0tl01kq	1795	9	DIF	DIF	NNP
cord-010027-r0tl01kq	1795	10	over	over	IN
cord-010027-r0tl01kq	1795	11	the	the	DT
cord-010027-r0tl01kq	1795	12	last	last	JJ
cord-010027-r0tl01kq	1795	13	2	2	CD
cord-010027-r0tl01kq	1795	14	years	year	NNS
cord-010027-r0tl01kq	1795	15	to	to	TO
cord-010027-r0tl01kq	1795	16	assess	assess	VB
cord-010027-r0tl01kq	1795	17	changes	change	NNS
cord-010027-r0tl01kq	1795	18	in	in	IN
cord-010027-r0tl01kq	1795	19	practice	practice	NN
cord-010027-r0tl01kq	1795	20	.	.	.
cord-010027-r0tl01kq	1796	1	All	all	DT
cord-010027-r0tl01kq	1796	2	134	134	CD
cord-010027-r0tl01kq	1796	3	requests	request	NNS
cord-010027-r0tl01kq	1796	4	for	for	IN
cord-010027-r0tl01kq	1796	5	DIF	DIF	NNP
cord-010027-r0tl01kq	1796	6	were	be	VBD
cord-010027-r0tl01kq	1796	7	granted	grant	VBN
cord-010027-r0tl01kq	1796	8	in	in	IN
cord-010027-r0tl01kq	1796	9	line	line	NN
cord-010027-r0tl01kq	1796	10	with	with	IN
cord-010027-r0tl01kq	1796	11	current	current	JJ
cord-010027-r0tl01kq	1796	12	departmental	departmental	JJ
cord-010027-r0tl01kq	1796	13	policy	policy	NN
cord-010027-r0tl01kq	1796	14	.	.	.
cord-010027-r0tl01kq	1797	1	The	the	DT
cord-010027-r0tl01kq	1797	2	indication	indication	NN
cord-010027-r0tl01kq	1797	3	categories	category	NNS
cord-010027-r0tl01kq	1797	4	were	be	VBD
cord-010027-r0tl01kq	1797	5	divided	divide	VBN
cord-010027-r0tl01kq	1797	6	as	as	IN
cord-010027-r0tl01kq	1797	7	follows	follow	VBZ
cord-010027-r0tl01kq	1797	8	:	:	:
cord-010027-r0tl01kq	1797	9	bullous	bullous	JJ
cord-010027-r0tl01kq	1797	10	41	41	CD
cord-010027-r0tl01kq	1797	11	,	,	,
cord-010027-r0tl01kq	1797	12	alopecia	alopecia	NNP
cord-010027-r0tl01kq	1797	13	4	4	CD
cord-010027-r0tl01kq	1797	14	,	,	,
cord-010027-r0tl01kq	1797	15	lupus	lupus	NN
cord-010027-r0tl01kq	1797	16	32	32	CD
cord-010027-r0tl01kq	1797	17	,	,	,
cord-010027-r0tl01kq	1797	18	vasculitis	vasculitis	JJ
cord-010027-r0tl01kq	1797	19	23	23	CD
cord-010027-r0tl01kq	1797	20	,	,	,
cord-010027-r0tl01kq	1797	21	dermatitis	dermatitis	NN
cord-010027-r0tl01kq	1797	22	herpetiformis	herpetiformis	NNP
cord-010027-r0tl01kq	1797	23	(	(	-LRB-
cord-010027-r0tl01kq	1797	24	DH	DH	NNP
cord-010027-r0tl01kq	1797	25	)	)	-RRB-
cord-010027-r0tl01kq	1798	1	15	15	CD
cord-010027-r0tl01kq	1798	2	and	and	CC
cord-010027-r0tl01kq	1798	3	'	'	``
cord-010027-r0tl01kq	1798	4	other	other	JJ
cord-010027-r0tl01kq	1798	5	'	'	POS
cord-010027-r0tl01kq	1798	6	19	19	CD
cord-010027-r0tl01kq	1798	7	.	.	.
cord-010027-r0tl01kq	1799	1	All	all	DT
cord-010027-r0tl01kq	1799	2	requests	request	NNS
cord-010027-r0tl01kq	1799	3	for	for	IN
cord-010027-r0tl01kq	1799	4	DIF	DIF	NNP
cord-010027-r0tl01kq	1799	5	were	be	VBD
cord-010027-r0tl01kq	1799	6	deemed	deem	VBN
cord-010027-r0tl01kq	1799	7	to	to	TO
cord-010027-r0tl01kq	1799	8	be	be	VB
cord-010027-r0tl01kq	1799	9	indicated	indicate	VBN
cord-010027-r0tl01kq	1799	10	in	in	IN
cord-010027-r0tl01kq	1799	11	both	both	CC
cord-010027-r0tl01kq	1799	12	the	the	DT
cord-010027-r0tl01kq	1799	13	bullous	bullous	JJ
cord-010027-r0tl01kq	1799	14	and	and	CC
cord-010027-r0tl01kq	1799	15	DH	DH	NNP
cord-010027-r0tl01kq	1799	16	categories	category	NNS
cord-010027-r0tl01kq	1799	17	by	by	IN
cord-010027-r0tl01kq	1799	18	our	-PRON-	PRP$
cord-010027-r0tl01kq	1799	19	panel	panel	NN
cord-010027-r0tl01kq	1799	20	,	,	,
cord-010027-r0tl01kq	1799	21	but	but	CC
cord-010027-r0tl01kq	1799	22	indicated	indicate	VBD
cord-010027-r0tl01kq	1799	23	requests	request	NNS
cord-010027-r0tl01kq	1799	24	varied	varied	JJ
cord-010027-r0tl01kq	1799	25	from	from	IN
cord-010027-r0tl01kq	1799	26	8.7	8.7	CD
cord-010027-r0tl01kq	1799	27	%	%	NN
cord-010027-r0tl01kq	1799	28	to	to	IN
cord-010027-r0tl01kq	1799	29	50	50	CD
cord-010027-r0tl01kq	1799	30	%	%	NN
cord-010027-r0tl01kq	1799	31	in	in	IN
cord-010027-r0tl01kq	1799	32	the	the	DT
cord-010027-r0tl01kq	1799	33	remaining	remain	VBG
cord-010027-r0tl01kq	1799	34	categories	category	NNS
cord-010027-r0tl01kq	1799	35	.	.	.
cord-010027-r0tl01kq	1800	1	In	in	IN
cord-010027-r0tl01kq	1800	2	45.5	45.5	CD
cord-010027-r0tl01kq	1800	3	%	%	NN
cord-010027-r0tl01kq	1800	4	(	(	-LRB-
cord-010027-r0tl01kq	1800	5	61	61	CD
cord-010027-r0tl01kq	1800	6	out	out	IN
cord-010027-r0tl01kq	1800	7	of	of	IN
cord-010027-r0tl01kq	1800	8	134	134	CD
cord-010027-r0tl01kq	1800	9	)	)	-RRB-
cord-010027-r0tl01kq	1800	10	of	of	IN
cord-010027-r0tl01kq	1800	11	cases	case	NNS
cord-010027-r0tl01kq	1800	12	DIF	DIF	NNP
cord-010027-r0tl01kq	1800	13	was	be	VBD
cord-010027-r0tl01kq	1800	14	deemed	deem	VBN
cord-010027-r0tl01kq	1800	15	to	to	TO
cord-010027-r0tl01kq	1800	16	be	be	VB
cord-010027-r0tl01kq	1800	17	contributory	contributory	JJ
cord-010027-r0tl01kq	1800	18	to	to	IN
cord-010027-r0tl01kq	1800	19	the	the	DT
cord-010027-r0tl01kq	1800	20	final	final	JJ
cord-010027-r0tl01kq	1800	21	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1800	22	.	.	.
cord-010027-r0tl01kq	1801	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1801	2	analysis	analysis	NN
cord-010027-r0tl01kq	1801	3	also	also	RB
cord-010027-r0tl01kq	1801	4	showed	show	VBD
cord-010027-r0tl01kq	1801	5	that	that	IN
cord-010027-r0tl01kq	1801	6	usage	usage	NN
cord-010027-r0tl01kq	1801	7	of	of	IN
cord-010027-r0tl01kq	1801	8	DIF	DIF	NNP
cord-010027-r0tl01kq	1801	9	in	in	IN
cord-010027-r0tl01kq	1801	10	our	-PRON-	PRP$
cord-010027-r0tl01kq	1801	11	department	department	NN
cord-010027-r0tl01kq	1801	12	is	be	VBZ
cord-010027-r0tl01kq	1801	13	escalating	escalate	VBG
cord-010027-r0tl01kq	1801	14	,	,	,
cord-010027-r0tl01kq	1801	15	with	with	IN
cord-010027-r0tl01kq	1801	16	a	a	DT
cord-010027-r0tl01kq	1801	17	23.2	23.2	CD
cord-010027-r0tl01kq	1801	18	%	%	NN
cord-010027-r0tl01kq	1801	19	increase	increase	NN
cord-010027-r0tl01kq	1801	20	in	in	IN
cord-010027-r0tl01kq	1801	21	requests	request	NNS
cord-010027-r0tl01kq	1801	22	from	from	IN
cord-010027-r0tl01kq	1801	23	2013	2013	CD
cord-010027-r0tl01kq	1801	24	to	to	IN
cord-010027-r0tl01kq	1801	25	2014	2014	CD
cord-010027-r0tl01kq	1801	26	.	.	.
cord-010027-r0tl01kq	1802	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1802	2	departmental	departmental	JJ
cord-010027-r0tl01kq	1802	3	policy	policy	NN
cord-010027-r0tl01kq	1802	4	with	with	IN
cord-010027-r0tl01kq	1802	5	regard	regard	NN
cord-010027-r0tl01kq	1802	6	to	to	IN
cord-010027-r0tl01kq	1802	7	DIF	DIF	NNP
cord-010027-r0tl01kq	1802	8	is	be	VBZ
cord-010027-r0tl01kq	1802	9	inclusive	inclusive	JJ
cord-010027-r0tl01kq	1802	10	and	and	CC
cord-010027-r0tl01kq	1802	11	operates	operate	VBZ
cord-010027-r0tl01kq	1802	12	solely	solely	RB
cord-010027-r0tl01kq	1802	13	on	on	IN
cord-010027-r0tl01kq	1802	14	the	the	DT
cord-010027-r0tl01kq	1802	15	basis	basis	NN
cord-010027-r0tl01kq	1802	16	of	of	IN
cord-010027-r0tl01kq	1802	17	clinician	clinician	NN
cord-010027-r0tl01kq	1802	18	request	request	NN
cord-010027-r0tl01kq	1802	19	.	.	.
cord-010027-r0tl01kq	1803	1	With	with	IN
cord-010027-r0tl01kq	1803	2	the	the	DT
cord-010027-r0tl01kq	1803	3	increasing	increase	VBG
cord-010027-r0tl01kq	1803	4	usage	usage	NN
cord-010027-r0tl01kq	1803	5	of	of	IN
cord-010027-r0tl01kq	1803	6	DIF	DIF	NNP
cord-010027-r0tl01kq	1803	7	,	,	,
cord-010027-r0tl01kq	1803	8	established	establish	VBD
cord-010027-r0tl01kq	1803	9	departmental	departmental	JJ
cord-010027-r0tl01kq	1803	10	guidelines	guideline	NNS
cord-010027-r0tl01kq	1803	11	and/or	and/or	CC
cord-010027-r0tl01kq	1803	12	a	a	DT
cord-010027-r0tl01kq	1803	13	protocol	protocol	NN
cord-010027-r0tl01kq	1803	14	for	for	IN
cord-010027-r0tl01kq	1803	15	DIF	DIF	NNP
cord-010027-r0tl01kq	1803	16	usage	usage	NN
cord-010027-r0tl01kq	1803	17	should	should	MD
cord-010027-r0tl01kq	1803	18	be	be	VB
cord-010027-r0tl01kq	1803	19	mutually	mutually	RB
cord-010027-r0tl01kq	1803	20	agreed	agree	VBN
cord-010027-r0tl01kq	1803	21	with	with	IN
cord-010027-r0tl01kq	1803	22	dermatology	dermatology	NN
cord-010027-r0tl01kq	1803	23	colleagues	colleague	NNS
cord-010027-r0tl01kq	1803	24	in	in	IN
cord-010027-r0tl01kq	1803	25	order	order	NN
cord-010027-r0tl01kq	1803	26	to	to	TO
cord-010027-r0tl01kq	1803	27	ensure	ensure	VB
cord-010027-r0tl01kq	1803	28	effective	effective	JJ
cord-010027-r0tl01kq	1803	29	use	use	NN
cord-010027-r0tl01kq	1803	30	of	of	IN
cord-010027-r0tl01kq	1803	31	this	this	DT
cord-010027-r0tl01kq	1803	32	expensive	expensive	JJ
cord-010027-r0tl01kq	1803	33	test	test	NN
cord-010027-r0tl01kq	1803	34	.	.	.
cord-010027-r0tl01kq	1804	1	Overview	Overview	NNP
cord-010027-r0tl01kq	1804	2	of	of	IN
cord-010027-r0tl01kq	1804	3	Merkel	Merkel	NNP
cord-010027-r0tl01kq	1804	4	Cell	Cell	NNP
cord-010027-r0tl01kq	1804	5	Carcinoma	Carcinoma	NNP
cord-010027-r0tl01kq	1804	6	in	in	IN
cord-010027-r0tl01kq	1804	7	an	an	DT
cord-010027-r0tl01kq	1804	8	Irish	irish	JJ
cord-010027-r0tl01kq	1804	9	Population	Population	NNP
cord-010027-r0tl01kq	1804	10	P	P	NNP
cord-010027-r0tl01kq	1804	11	A	A	NNP
cord-010027-r0tl01kq	1804	12	Cooper	Cooper	NNP
cord-010027-r0tl01kq	1804	13	1	1	CD
cord-010027-r0tl01kq	1804	14	;	;	:
cord-010027-r0tl01kq	1804	15	J	J	NNP
cord-010027-r0tl01kq	1804	16	Thorne	Thorne	NNP
cord-010027-r0tl01kq	1804	17	2	2	CD
cord-010027-r0tl01kq	1804	18	1	1	CD
cord-010027-r0tl01kq	1804	19	Royal	Royal	NNP
cord-010027-r0tl01kq	1804	20	College	College	NNP
cord-010027-r0tl01kq	1804	21	of	of	IN
cord-010027-r0tl01kq	1804	22	Surgeons	Surgeons	NNPS
cord-010027-r0tl01kq	1804	23	in	in	IN
cord-010027-r0tl01kq	1804	24	Ireland	Ireland	NNP
cord-010027-r0tl01kq	1804	25	,	,	,
cord-010027-r0tl01kq	1804	26	Dublin	Dublin	NNP
cord-010027-r0tl01kq	1804	27	,	,	,
cord-010027-r0tl01kq	1804	28	Ireland	Ireland	NNP
cord-010027-r0tl01kq	1804	29	;	;	:
cord-010027-r0tl01kq	1804	30	2	2	CD
cord-010027-r0tl01kq	1804	31	Beaumont	Beaumont	NNP
cord-010027-r0tl01kq	1804	32	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1804	33	,	,	,
cord-010027-r0tl01kq	1804	34	Dublin	Dublin	NNP
cord-010027-r0tl01kq	1804	35	,	,	,
cord-010027-r0tl01kq	1804	36	Ireland	Ireland	NNP
cord-010027-r0tl01kq	1804	37	Purpose	Purpose	NNP
cord-010027-r0tl01kq	1804	38	of	of	IN
cord-010027-r0tl01kq	1804	39	Study	Study	NNP
cord-010027-r0tl01kq	1804	40	:	:	:
cord-010027-r0tl01kq	1804	41	Merkel	Merkel	NNP
cord-010027-r0tl01kq	1804	42	cell	cell	NN
cord-010027-r0tl01kq	1804	43	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1804	44	(	(	-LRB-
cord-010027-r0tl01kq	1804	45	MCC	MCC	NNP
cord-010027-r0tl01kq	1804	46	)	)	-RRB-
cord-010027-r0tl01kq	1804	47	is	be	VBZ
cord-010027-r0tl01kq	1804	48	an	an	DT
cord-010027-r0tl01kq	1804	49	uncommon	uncommon	JJ
cord-010027-r0tl01kq	1804	50	but	but	CC
cord-010027-r0tl01kq	1804	51	highly	highly	RB
cord-010027-r0tl01kq	1804	52	aggressive	aggressive	JJ
cord-010027-r0tl01kq	1804	53	primary	primary	JJ
cord-010027-r0tl01kq	1804	54	cutaneous	cutaneous	JJ
cord-010027-r0tl01kq	1804	55	malignancy	malignancy	NN
cord-010027-r0tl01kq	1804	56	of	of	IN
cord-010027-r0tl01kq	1804	57	neuroendocrine	neuroendocrine	JJ
cord-010027-r0tl01kq	1804	58	cells	cell	NNS
cord-010027-r0tl01kq	1804	59	with	with	IN
cord-010027-r0tl01kq	1804	60	a	a	DT
cord-010027-r0tl01kq	1804	61	propensity	propensity	NN
cord-010027-r0tl01kq	1804	62	for	for	IN
cord-010027-r0tl01kq	1804	63	regional	regional	JJ
cord-010027-r0tl01kq	1804	64	and	and	CC
cord-010027-r0tl01kq	1804	65	distal	distal	JJ
cord-010027-r0tl01kq	1804	66	metastases	metastasis	NNS
cord-010027-r0tl01kq	1804	67	.	.	.
cord-010027-r0tl01kq	1805	1	Due	due	IN
cord-010027-r0tl01kq	1805	2	to	to	IN
cord-010027-r0tl01kq	1805	3	it	-PRON-	PRP
cord-010027-r0tl01kq	1805	4	's	be	VBZ
cord-010027-r0tl01kq	1805	5	rarity	rarity	NN
cord-010027-r0tl01kq	1805	6	,	,	,
cord-010027-r0tl01kq	1805	7	information	information	NN
cord-010027-r0tl01kq	1805	8	relating	relate	VBG
cord-010027-r0tl01kq	1805	9	to	to	IN
cord-010027-r0tl01kq	1805	10	it	-PRON-	PRP
cord-010027-r0tl01kq	1805	11	's	be	VBZ
cord-010027-r0tl01kq	1805	12	epidemiology	epidemiology	NN
cord-010027-r0tl01kq	1805	13	in	in	IN
cord-010027-r0tl01kq	1805	14	an	an	DT
cord-010027-r0tl01kq	1805	15	Irish	irish	JJ
cord-010027-r0tl01kq	1805	16	population	population	NN
cord-010027-r0tl01kq	1805	17	is	be	VBZ
cord-010027-r0tl01kq	1805	18	limited	limit	VBN
cord-010027-r0tl01kq	1805	19	,	,	,
cord-010027-r0tl01kq	1805	20	mainly	mainly	RB
cord-010027-r0tl01kq	1805	21	owing	owe	VBG
cord-010027-r0tl01kq	1805	22	to	to	IN
cord-010027-r0tl01kq	1805	23	difficulty	difficulty	NN
cord-010027-r0tl01kq	1805	24	in	in	IN
cord-010027-r0tl01kq	1805	25	gathering	gather	VBG
cord-010027-r0tl01kq	1805	26	large	large	JJ
cord-010027-r0tl01kq	1805	27	patient	patient	JJ
cord-010027-r0tl01kq	1805	28	series	series	NN
cord-010027-r0tl01kq	1805	29	.	.	.
cord-010027-r0tl01kq	1806	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1806	2	aim	aim	NN
cord-010027-r0tl01kq	1806	3	was	be	VBD
cord-010027-r0tl01kq	1806	4	to	to	TO
cord-010027-r0tl01kq	1806	5	identify	identify	VB
cord-010027-r0tl01kq	1806	6	all	all	DT
cord-010027-r0tl01kq	1806	7	cases	case	NNS
cord-010027-r0tl01kq	1806	8	of	of	IN
cord-010027-r0tl01kq	1806	9	MCC	MCC	NNP
cord-010027-r0tl01kq	1806	10	in	in	IN
cord-010027-r0tl01kq	1806	11	our	-PRON-	PRP$
cord-010027-r0tl01kq	1806	12	institution	institution	NN
cord-010027-r0tl01kq	1806	13	in	in	IN
cord-010027-r0tl01kq	1806	14	a	a	DT
cord-010027-r0tl01kq	1806	15	defined	define	VBN
cord-010027-r0tl01kq	1806	16	10	10	CD
cord-010027-r0tl01kq	1806	17	year	year	NN
cord-010027-r0tl01kq	1806	18	period	period	NN
cord-010027-r0tl01kq	1806	19	and	and	CC
cord-010027-r0tl01kq	1806	20	review	review	VB
cord-010027-r0tl01kq	1806	21	the	the	DT
cord-010027-r0tl01kq	1806	22	patient	patient	JJ
cord-010027-r0tl01kq	1806	23	demographics	demographic	NNS
cord-010027-r0tl01kq	1806	24	compared	compare	VBN
cord-010027-r0tl01kq	1806	25	to	to	IN
cord-010027-r0tl01kq	1806	26	internationally	internationally	RB
cord-010027-r0tl01kq	1806	27	available	available	JJ
cord-010027-r0tl01kq	1806	28	data	datum	NNS
cord-010027-r0tl01kq	1806	29	.	.	.
cord-010027-r0tl01kq	1807	1	A	a	DT
cord-010027-r0tl01kq	1807	2	search	search	NN
cord-010027-r0tl01kq	1807	3	was	be	VBD
cord-010027-r0tl01kq	1807	4	carried	carry	VBN
cord-010027-r0tl01kq	1807	5	out	out	RP
cord-010027-r0tl01kq	1807	6	on	on	IN
cord-010027-r0tl01kq	1807	7	the	the	DT
cord-010027-r0tl01kq	1807	8	hospital	hospital	NN
cord-010027-r0tl01kq	1807	9	laboratory	laboratory	NN
cord-010027-r0tl01kq	1807	10	system	system	NN
cord-010027-r0tl01kq	1807	11	to	to	TO
cord-010027-r0tl01kq	1807	12	identify	identify	VB
cord-010027-r0tl01kq	1807	13	all	all	DT
cord-010027-r0tl01kq	1807	14	cases	case	NNS
cord-010027-r0tl01kq	1807	15	of	of	IN
cord-010027-r0tl01kq	1807	16	MCC	MCC	NNP
cord-010027-r0tl01kq	1807	17	from	from	IN
cord-010027-r0tl01kq	1807	18	01/01/2005	01/01/2005	CD
cord-010027-r0tl01kq	1807	19	to	to	IN
cord-010027-r0tl01kq	1807	20	21/12/2014	21/12/2014	CD
cord-010027-r0tl01kq	1807	21	.	.	.
cord-010027-r0tl01kq	1808	1	All	all	DT
cord-010027-r0tl01kq	1808	2	histology	histology	NN
cord-010027-r0tl01kq	1808	3	reports	report	NNS
cord-010027-r0tl01kq	1808	4	were	be	VBD
cord-010027-r0tl01kq	1808	5	reviewed	review	VBN
cord-010027-r0tl01kq	1808	6	and	and	CC
cord-010027-r0tl01kq	1808	7	any	any	DT
cord-010027-r0tl01kq	1808	8	information	information	NN
cord-010027-r0tl01kq	1808	9	pertaining	pertain	VBG
cord-010027-r0tl01kq	1808	10	to	to	IN
cord-010027-r0tl01kq	1808	11	patient	patient	JJ
cord-010027-r0tl01kq	1808	12	demographics	demographic	NNS
cord-010027-r0tl01kq	1808	13	was	be	VBD
cord-010027-r0tl01kq	1808	14	recorded	record	VBN
cord-010027-r0tl01kq	1808	15	in	in	IN
cord-010027-r0tl01kq	1808	16	an	an	DT
cord-010027-r0tl01kq	1808	17	excel	excel	JJ
cord-010027-r0tl01kq	1808	18	spreadsheet	spreadsheet	NN
cord-010027-r0tl01kq	1808	19	.	.	.
cord-010027-r0tl01kq	1809	1	A	a	DT
cord-010027-r0tl01kq	1809	2	literature	literature	NN
cord-010027-r0tl01kq	1809	3	review	review	NN
cord-010027-r0tl01kq	1809	4	was	be	VBD
cord-010027-r0tl01kq	1809	5	performed	perform	VBN
cord-010027-r0tl01kq	1809	6	relating	relate	VBG
cord-010027-r0tl01kq	1809	7	to	to	IN
cord-010027-r0tl01kq	1809	8	the	the	DT
cord-010027-r0tl01kq	1809	9	patient	patient	JJ
cord-010027-r0tl01kq	1809	10	profile	profile	NN
cord-010027-r0tl01kq	1809	11	of	of	IN
cord-010027-r0tl01kq	1809	12	MCC	MCC	NNP
cord-010027-r0tl01kq	1809	13	internationally	internationally	RB
cord-010027-r0tl01kq	1809	14	and	and	CC
cord-010027-r0tl01kq	1809	15	the	the	DT
cord-010027-r0tl01kq	1809	16	results	result	NNS
cord-010027-r0tl01kq	1809	17	were	be	VBD
cord-010027-r0tl01kq	1809	18	compared	compare	VBN
cord-010027-r0tl01kq	1809	19	.	.	.
cord-010027-r0tl01kq	1810	1	Results	result	NNS
cord-010027-r0tl01kq	1810	2	:	:	:
cord-010027-r0tl01kq	1811	1	A	a	DT
cord-010027-r0tl01kq	1811	2	total	total	NN
cord-010027-r0tl01kq	1811	3	of	of	IN
cord-010027-r0tl01kq	1811	4	33	33	CD
cord-010027-r0tl01kq	1811	5	reports	report	NNS
cord-010027-r0tl01kq	1811	6	pertaining	pertain	VBG
cord-010027-r0tl01kq	1811	7	to	to	IN
cord-010027-r0tl01kq	1811	8	25	25	CD
cord-010027-r0tl01kq	1811	9	individual	individual	JJ
cord-010027-r0tl01kq	1811	10	patients	patient	NNS
cord-010027-r0tl01kq	1811	11	were	be	VBD
cord-010027-r0tl01kq	1811	12	recovered	recover	VBN
cord-010027-r0tl01kq	1811	13	.	.	.
cord-010027-r0tl01kq	1812	1	All	all	DT
cord-010027-r0tl01kq	1812	2	patients	patient	NNS
cord-010027-r0tl01kq	1812	3	were	be	VBD
cord-010027-r0tl01kq	1812	4	of	of	IN
cord-010027-r0tl01kq	1812	5	Caucasian	caucasian	JJ
cord-010027-r0tl01kq	1812	6	Irish	irish	JJ
cord-010027-r0tl01kq	1812	7	ethnicity	ethnicity	NN
cord-010027-r0tl01kq	1812	8	.	.	.
cord-010027-r0tl01kq	1813	1	The	the	DT
cord-010027-r0tl01kq	1813	2	incidence	incidence	NN
cord-010027-r0tl01kq	1813	3	of	of	IN
cord-010027-r0tl01kq	1813	4	MCC	MCC	NNP
cord-010027-r0tl01kq	1813	5	was	be	VBD
cord-010027-r0tl01kq	1813	6	higher	high	JJR
cord-010027-r0tl01kq	1813	7	in	in	IN
cord-010027-r0tl01kq	1813	8	men	man	NNS
cord-010027-r0tl01kq	1813	9	(	(	-LRB-
cord-010027-r0tl01kq	1813	10	56	56	CD
cord-010027-r0tl01kq	1813	11	%	%	NN
cord-010027-r0tl01kq	1813	12	of	of	IN
cord-010027-r0tl01kq	1813	13	cases	case	NNS
cord-010027-r0tl01kq	1813	14	,	,	,
cord-010027-r0tl01kq	1813	15	n=14	n=14	JJ
cord-010027-r0tl01kq	1813	16	)	)	-RRB-
cord-010027-r0tl01kq	1813	17	than	than	IN
cord-010027-r0tl01kq	1813	18	women	woman	NNS
cord-010027-r0tl01kq	1813	19	.	.	.
cord-010027-r0tl01kq	1814	1	The	the	DT
cord-010027-r0tl01kq	1814	2	median	median	JJ
cord-010027-r0tl01kq	1814	3	age	age	NN
cord-010027-r0tl01kq	1814	4	at	at	IN
cord-010027-r0tl01kq	1814	5	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1814	6	was	be	VBD
cord-010027-r0tl01kq	1814	7	80	80	CD
cord-010027-r0tl01kq	1814	8	years	year	NNS
cord-010027-r0tl01kq	1815	1	(	(	-LRB-
cord-010027-r0tl01kq	1815	2	range	range	NN
cord-010027-r0tl01kq	1815	3	57	57	CD
cord-010027-r0tl01kq	1815	4	-	-	SYM
cord-010027-r0tl01kq	1815	5	90	90	CD
cord-010027-r0tl01kq	1815	6	)	)	-RRB-
cord-010027-r0tl01kq	1815	7	.	.	.
cord-010027-r0tl01kq	1816	1	Men	man	NNS
cord-010027-r0tl01kq	1816	2	presented	present	VBN
cord-010027-r0tl01kq	1816	3	at	at	IN
cord-010027-r0tl01kq	1816	4	an	an	DT
cord-010027-r0tl01kq	1816	5	earlier	early	JJR
cord-010027-r0tl01kq	1816	6	age	age	NN
cord-010027-r0tl01kq	1816	7	(	(	-LRB-
cord-010027-r0tl01kq	1816	8	median	median	NN
cord-010027-r0tl01kq	1816	9	78	78	CD
cord-010027-r0tl01kq	1816	10	years	year	NNS
cord-010027-r0tl01kq	1816	11	)	)	-RRB-
cord-010027-r0tl01kq	1816	12	than	than	IN
cord-010027-r0tl01kq	1816	13	women	woman	NNS
cord-010027-r0tl01kq	1816	14	(	(	-LRB-
cord-010027-r0tl01kq	1816	15	median	median	JJ
cord-010027-r0tl01kq	1816	16	83	83	CD
cord-010027-r0tl01kq	1816	17	years	year	NNS
cord-010027-r0tl01kq	1816	18	)	)	-RRB-
cord-010027-r0tl01kq	1816	19	.	.	.
cord-010027-r0tl01kq	1817	1	Regarding	regard	VBG
cord-010027-r0tl01kq	1817	2	the	the	DT
cord-010027-r0tl01kq	1817	3	anatomic	anatomic	JJ
cord-010027-r0tl01kq	1817	4	site	site	NN
cord-010027-r0tl01kq	1817	5	of	of	IN
cord-010027-r0tl01kq	1817	6	the	the	DT
cord-010027-r0tl01kq	1817	7	tumours	tumour	NNS
cord-010027-r0tl01kq	1817	8	,	,	,
cord-010027-r0tl01kq	1817	9	64	64	CD
cord-010027-r0tl01kq	1817	10	%	%	NN
cord-010027-r0tl01kq	1817	11	(	(	-LRB-
cord-010027-r0tl01kq	1817	12	n=16	n=16	NNP
cord-010027-r0tl01kq	1817	13	)	)	-RRB-
cord-010027-r0tl01kq	1817	14	were	be	VBD
cord-010027-r0tl01kq	1817	15	on	on	IN
cord-010027-r0tl01kq	1817	16	the	the	DT
cord-010027-r0tl01kq	1817	17	head	head	NN
cord-010027-r0tl01kq	1817	18	or	or	CC
cord-010027-r0tl01kq	1817	19	face	face	NN
cord-010027-r0tl01kq	1817	20	,	,	,
cord-010027-r0tl01kq	1817	21	20	20	CD
cord-010027-r0tl01kq	1817	22	%	%	NN
cord-010027-r0tl01kq	1817	23	(	(	-LRB-
cord-010027-r0tl01kq	1817	24	n=5	n=5	NNP
cord-010027-r0tl01kq	1817	25	)	)	-RRB-
cord-010027-r0tl01kq	1817	26	were	be	VBD
cord-010027-r0tl01kq	1817	27	on	on	IN
cord-010027-r0tl01kq	1817	28	the	the	DT
cord-010027-r0tl01kq	1817	29	lower	low	JJR
cord-010027-r0tl01kq	1817	30	limb	limb	NN
cord-010027-r0tl01kq	1817	31	and	and	CC
cord-010027-r0tl01kq	1817	32	12	12	CD
cord-010027-r0tl01kq	1817	33	%	%	NN
cord-010027-r0tl01kq	1817	34	(	(	-LRB-
cord-010027-r0tl01kq	1817	35	n=3	n=3	NN
cord-010027-r0tl01kq	1817	36	)	)	-RRB-
cord-010027-r0tl01kq	1817	37	were	be	VBD
cord-010027-r0tl01kq	1817	38	on	on	IN
cord-010027-r0tl01kq	1817	39	the	the	DT
cord-010027-r0tl01kq	1817	40	upper	upper	JJ
cord-010027-r0tl01kq	1817	41	limb	limb	NN
cord-010027-r0tl01kq	1817	42	.	.	.
cord-010027-r0tl01kq	1818	1	All	all	DT
cord-010027-r0tl01kq	1818	2	were	be	VBD
cord-010027-r0tl01kq	1818	3	on	on	IN
cord-010027-r0tl01kq	1818	4	sun	sun	NN
cord-010027-r0tl01kq	1818	5	-	-	HYPH
cord-010027-r0tl01kq	1818	6	exposed	expose	VBN
cord-010027-r0tl01kq	1818	7	sites	site	NNS
cord-010027-r0tl01kq	1818	8	.	.	.
cord-010027-r0tl01kq	1819	1	Of	of	IN
cord-010027-r0tl01kq	1819	2	note	note	NN
cord-010027-r0tl01kq	1819	3	,	,	,
cord-010027-r0tl01kq	1819	4	the	the	DT
cord-010027-r0tl01kq	1819	5	majority	majority	NN
cord-010027-r0tl01kq	1819	6	of	of	IN
cord-010027-r0tl01kq	1819	7	tumours	tumour	NNS
cord-010027-r0tl01kq	1819	8	in	in	IN
cord-010027-r0tl01kq	1819	9	the	the	DT
cord-010027-r0tl01kq	1819	10	male	male	JJ
cord-010027-r0tl01kq	1819	11	population	population	NN
cord-010027-r0tl01kq	1819	12	were	be	VBD
cord-010027-r0tl01kq	1819	13	on	on	IN
cord-010027-r0tl01kq	1819	14	the	the	DT
cord-010027-r0tl01kq	1819	15	head	head	NN
cord-010027-r0tl01kq	1819	16	(	(	-LRB-
cord-010027-r0tl01kq	1819	17	78.6	78.6	CD
cord-010027-r0tl01kq	1819	18	%	%	NN
cord-010027-r0tl01kq	1819	19	,	,	,
cord-010027-r0tl01kq	1819	20	n=11	n=11	NNP
cord-010027-r0tl01kq	1819	21	)	)	-RRB-
cord-010027-r0tl01kq	1819	22	,	,	,
cord-010027-r0tl01kq	1819	23	while	while	IN
cord-010027-r0tl01kq	1819	24	the	the	DT
cord-010027-r0tl01kq	1819	25	female	female	JJ
cord-010027-r0tl01kq	1819	26	population	population	NN
cord-010027-r0tl01kq	1819	27	showed	show	VBD
cord-010027-r0tl01kq	1819	28	an	an	DT
cord-010027-r0tl01kq	1819	29	equal	equal	JJ
cord-010027-r0tl01kq	1819	30	distribution	distribution	NN
cord-010027-r0tl01kq	1819	31	between	between	IN
cord-010027-r0tl01kq	1819	32	the	the	DT
cord-010027-r0tl01kq	1819	33	head	head	NN
cord-010027-r0tl01kq	1819	34	and	and	CC
cord-010027-r0tl01kq	1819	35	the	the	DT
cord-010027-r0tl01kq	1819	36	lower	low	JJR
cord-010027-r0tl01kq	1819	37	limbs	limb	NNS
cord-010027-r0tl01kq	1819	38	(	(	-LRB-
cord-010027-r0tl01kq	1819	39	45	45	CD
cord-010027-r0tl01kq	1819	40	%	%	NN
cord-010027-r0tl01kq	1819	41	,	,	,
cord-010027-r0tl01kq	1819	42	n=5	n=5	JJ
cord-010027-r0tl01kq	1819	43	for	for	IN
cord-010027-r0tl01kq	1819	44	each	each	DT
cord-010027-r0tl01kq	1819	45	sub	sub	NN
cord-010027-r0tl01kq	1819	46	-	-	JJ
cord-010027-r0tl01kq	1819	47	site	site	NN
cord-010027-r0tl01kq	1819	48	)	)	-RRB-
cord-010027-r0tl01kq	1819	49	.	.	.
cord-010027-r0tl01kq	1820	1	The	the	DT
cord-010027-r0tl01kq	1820	2	subset	subset	NN
cord-010027-r0tl01kq	1820	3	of	of	IN
cord-010027-r0tl01kq	1820	4	patients	patient	NNS
cord-010027-r0tl01kq	1820	5	we	-PRON-	PRP
cord-010027-r0tl01kq	1820	6	identified	identify	VBD
cord-010027-r0tl01kq	1820	7	show	show	VBP
cord-010027-r0tl01kq	1820	8	demographics	demographic	NNS
cord-010027-r0tl01kq	1820	9	consistent	consistent	JJ
cord-010027-r0tl01kq	1820	10	with	with	IN
cord-010027-r0tl01kq	1820	11	published	publish	VBN
cord-010027-r0tl01kq	1820	12	literature	literature	NN
cord-010027-r0tl01kq	1820	13	for	for	IN
cord-010027-r0tl01kq	1820	14	US	US	NNP
cord-010027-r0tl01kq	1820	15	,	,	,
cord-010027-r0tl01kq	1820	16	Australian	australian	JJ
cord-010027-r0tl01kq	1820	17	and	and	CC
cord-010027-r0tl01kq	1820	18	other	other	JJ
cord-010027-r0tl01kq	1820	19	European	european	JJ
cord-010027-r0tl01kq	1820	20	cohorts	cohort	NNS
cord-010027-r0tl01kq	1820	21	.	.	.
cord-010027-r0tl01kq	1821	1	Merkel	Merkel	NNP
cord-010027-r0tl01kq	1821	2	Cell	Cell	NNP
cord-010027-r0tl01kq	1821	3	Carcinoma	Carcinoma	NNP
cord-010027-r0tl01kq	1821	4	is	be	VBZ
cord-010027-r0tl01kq	1821	5	a	a	DT
cord-010027-r0tl01kq	1821	6	disease	disease	NN
cord-010027-r0tl01kq	1821	7	of	of	IN
cord-010027-r0tl01kq	1821	8	the	the	DT
cord-010027-r0tl01kq	1821	9	elderly	elderly	JJ
cord-010027-r0tl01kq	1821	10	affecting	affect	VBG
cord-010027-r0tl01kq	1821	11	sun	sun	NN
cord-010027-r0tl01kq	1821	12	-	-	HYPH
cord-010027-r0tl01kq	1821	13	exposed	expose	VBN
cord-010027-r0tl01kq	1821	14	sites	site	NNS
cord-010027-r0tl01kq	1821	15	.	.	.
cord-010027-r0tl01kq	1822	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1822	2	note	note	VBP
cord-010027-r0tl01kq	1822	3	some	some	DT
cord-010027-r0tl01kq	1822	4	variation	variation	NN
cord-010027-r0tl01kq	1822	5	in	in	IN
cord-010027-r0tl01kq	1822	6	the	the	DT
cord-010027-r0tl01kq	1822	7	dominant	dominant	JJ
cord-010027-r0tl01kq	1822	8	anatomic	anatomic	JJ
cord-010027-r0tl01kq	1822	9	sites	site	NNS
cord-010027-r0tl01kq	1822	10	between	between	IN
cord-010027-r0tl01kq	1822	11	genders	gender	NNS
cord-010027-r0tl01kq	1822	12	and	and	CC
cord-010027-r0tl01kq	1822	13	conclude	conclude	VB
cord-010027-r0tl01kq	1822	14	this	this	DT
cord-010027-r0tl01kq	1822	15	is	be	VBZ
cord-010027-r0tl01kq	1822	16	due	due	JJ
cord-010027-r0tl01kq	1822	17	to	to	IN
cord-010027-r0tl01kq	1822	18	differing	differ	VBG
cord-010027-r0tl01kq	1822	19	environmental	environmental	JJ
cord-010027-r0tl01kq	1822	20	exposure	exposure	NN
cord-010027-r0tl01kq	1822	21	.	.	.
cord-010027-r0tl01kq	1823	1	Background	background	NN
cord-010027-r0tl01kq	1823	2	:	:	:
cord-010027-r0tl01kq	1824	1	A	a	DT
cord-010027-r0tl01kq	1824	2	novel	novel	JJ
cord-010027-r0tl01kq	1824	3	cell	cell	NN
cord-010027-r0tl01kq	1824	4	-	-	HYPH
cord-010027-r0tl01kq	1824	5	dispensing	dispense	VBG
cord-010027-r0tl01kq	1824	6	instrument	instrument	NN
cord-010027-r0tl01kq	1824	7	referred	refer	VBN
cord-010027-r0tl01kq	1824	8	to	to	IN
cord-010027-r0tl01kq	1824	9	as	as	IN
cord-010027-r0tl01kq	1824	10	a	a	DT
cord-010027-r0tl01kq	1824	11	Single	Single	NNP
cord-010027-r0tl01kq	1824	12	Cell	Cell	NNP
cord-010027-r0tl01kq	1824	13	Manipulator	manipulator	NN
cord-010027-r0tl01kq	1824	14	(	(	-LRB-
cord-010027-r0tl01kq	1824	15	SCM	SCM	NNP
cord-010027-r0tl01kq	1824	16	)	)	-RRB-
cord-010027-r0tl01kq	1824	17	device	device	NN
cord-010027-r0tl01kq	1824	18	was	be	VBD
cord-010027-r0tl01kq	1824	19	developed	develop	VBN
cord-010027-r0tl01kq	1824	20	with	with	IN
cord-010027-r0tl01kq	1824	21	the	the	DT
cord-010027-r0tl01kq	1824	22	following	follow	VBG
cord-010027-r0tl01kq	1824	23	features	feature	NNS
cord-010027-r0tl01kq	1824	24	:	:	:
cord-010027-r0tl01kq	1824	25	i	i	LS
cord-010027-r0tl01kq	1824	26	)	)	-RRB-
cord-010027-r0tl01kq	1824	27	rapid	rapid	JJ
cord-010027-r0tl01kq	1824	28	optical	optical	JJ
cord-010027-r0tl01kq	1824	29	and	and	CC
cord-010027-r0tl01kq	1824	30	fluorescent	fluorescent	JJ
cord-010027-r0tl01kq	1824	31	detection	detection	NN
cord-010027-r0tl01kq	1824	32	of	of	IN
cord-010027-r0tl01kq	1824	33	single	single	JJ
cord-010027-r0tl01kq	1824	34	cells	cell	NNS
cord-010027-r0tl01kq	1824	35	ii	ii	CD
cord-010027-r0tl01kq	1824	36	)	)	-RRB-
cord-010027-r0tl01kq	1824	37	generation	generation	NN
cord-010027-r0tl01kq	1824	38	of	of	IN
cord-010027-r0tl01kq	1824	39	picoliter	picoliter	NN
cord-010027-r0tl01kq	1824	40	sized	sized	JJ
cord-010027-r0tl01kq	1824	41	droplets	droplet	NNS
cord-010027-r0tl01kq	1824	42	encapsulating	encapsulate	VBG
cord-010027-r0tl01kq	1824	43	the	the	DT
cord-010027-r0tl01kq	1824	44	isolated	isolated	JJ
cord-010027-r0tl01kq	1824	45	single	single	JJ
cord-010027-r0tl01kq	1824	46	cell	cell	NN
cord-010027-r0tl01kq	1824	47	and	and	CC
cord-010027-r0tl01kq	1824	48	iii	iii	NN
cord-010027-r0tl01kq	1824	49	)	)	-RRB-
cord-010027-r0tl01kq	1824	50	printing	printing	NN
cord-010027-r0tl01kq	1824	51	of	of	IN
cord-010027-r0tl01kq	1824	52	the	the	DT
cord-010027-r0tl01kq	1824	53	single	single	JJ
cord-010027-r0tl01kq	1824	54	cell	cell	NN
cord-010027-r0tl01kq	1824	55	in	in	IN
cord-010027-r0tl01kq	1824	56	an	an	DT
cord-010027-r0tl01kq	1824	57	"	"	``
cord-010027-r0tl01kq	1824	58	ink	ink	NN
cord-010027-r0tl01kq	1824	59	-	-	HYPH
cord-010027-r0tl01kq	1824	60	jet	jet	NN
cord-010027-r0tl01kq	1824	61	"	"	''
cord-010027-r0tl01kq	1824	62	like	like	IN
cord-010027-r0tl01kq	1824	63	manner	manner	NN
cord-010027-r0tl01kq	1824	64	onto	onto	IN
cord-010027-r0tl01kq	1824	65	a	a	DT
cord-010027-r0tl01kq	1824	66	chosen	choose	VBN
cord-010027-r0tl01kq	1824	67	substrate	substrate	NN
cord-010027-r0tl01kq	1824	68	.	.	.
cord-010027-r0tl01kq	1825	1	This	this	DT
cord-010027-r0tl01kq	1825	2	technology	technology	NN
cord-010027-r0tl01kq	1825	3	was	be	VBD
cord-010027-r0tl01kq	1825	4	used	use	VBN
cord-010027-r0tl01kq	1825	5	to	to	TO
cord-010027-r0tl01kq	1825	6	isolate	isolate	VB
cord-010027-r0tl01kq	1825	7	cells	cell	NNS
cord-010027-r0tl01kq	1825	8	of	of	IN
cord-010027-r0tl01kq	1825	9	interest	interest	NN
cord-010027-r0tl01kq	1825	10	from	from	IN
cord-010027-r0tl01kq	1825	11	i	i	NNP
cord-010027-r0tl01kq	1825	12	)	)	-RRB-
cord-010027-r0tl01kq	1825	13	heterogeneous	heterogeneous	JJ
cord-010027-r0tl01kq	1825	14	mixed	mixed	JJ
cord-010027-r0tl01kq	1825	15	populations	population	NNS
cord-010027-r0tl01kq	1825	16	of	of	IN
cord-010027-r0tl01kq	1825	17	cells	cell	NNS
cord-010027-r0tl01kq	1825	18	,	,	,
cord-010027-r0tl01kq	1825	19	ii	ii	LS
cord-010027-r0tl01kq	1825	20	)	)	-RRB-
cord-010027-r0tl01kq	1825	21	co	co	NNS
cord-010027-r0tl01kq	1825	22	-	-	NNS
cord-010027-r0tl01kq	1825	23	cultures	culture	NNS
cord-010027-r0tl01kq	1825	24	of	of	IN
cord-010027-r0tl01kq	1825	25	cells	cell	NNS
cord-010027-r0tl01kq	1825	26	and	and	CC
cord-010027-r0tl01kq	1825	27	iii	iii	LS
cord-010027-r0tl01kq	1825	28	)	)	-RRB-
cord-010027-r0tl01kq	1825	29	clinical	clinical	JJ
cord-010027-r0tl01kq	1825	30	patient	patient	NN
cord-010027-r0tl01kq	1825	31	samples	sample	NNS
cord-010027-r0tl01kq	1825	32	for	for	IN
cord-010027-r0tl01kq	1825	33	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1825	34	downstream	downstream	JJ
cord-010027-r0tl01kq	1825	35	biological	biological	JJ
cord-010027-r0tl01kq	1825	36	analysis	analysis	NN
cord-010027-r0tl01kq	1825	37	.	.	.
cord-010027-r0tl01kq	1826	1	Methods	method	NNS
cord-010027-r0tl01kq	1826	2	:	:	:
cord-010027-r0tl01kq	1826	3	Cells	cell	NNS
cord-010027-r0tl01kq	1826	4	were	be	VBD
cord-010027-r0tl01kq	1826	5	injected	inject	VBN
cord-010027-r0tl01kq	1826	6	into	into	IN
cord-010027-r0tl01kq	1826	7	a	a	DT
cord-010027-r0tl01kq	1826	8	reusable	reusable	JJ
cord-010027-r0tl01kq	1826	9	silicon	silicon	NN
cord-010027-r0tl01kq	1826	10	dispenser	dispenser	NN
cord-010027-r0tl01kq	1826	11	chip	chip	NN
cord-010027-r0tl01kq	1826	12	that	that	WDT
cord-010027-r0tl01kq	1826	13	was	be	VBD
cord-010027-r0tl01kq	1826	14	coupled	couple	VBN
cord-010027-r0tl01kq	1826	15	to	to	IN
cord-010027-r0tl01kq	1826	16	a	a	DT
cord-010027-r0tl01kq	1826	17	live	live	JJ
cord-010027-r0tl01kq	1826	18	cell	cell	NN
cord-010027-r0tl01kq	1826	19	camera	camera	NN
cord-010027-r0tl01kq	1826	20	for	for	IN
cord-010027-r0tl01kq	1826	21	image	image	NN
cord-010027-r0tl01kq	1826	22	capture	capture	NN
cord-010027-r0tl01kq	1826	23	and	and	CC
cord-010027-r0tl01kq	1826	24	display	display	NN
cord-010027-r0tl01kq	1826	25	of	of	IN
cord-010027-r0tl01kq	1826	26	cells	cell	NNS
cord-010027-r0tl01kq	1826	27	approaching	approach	VBG
cord-010027-r0tl01kq	1826	28	the	the	DT
cord-010027-r0tl01kq	1826	29	chip	chip	NN
cord-010027-r0tl01kq	1826	30	's	's	POS
cord-010027-r0tl01kq	1826	31	exit	exit	NN
cord-010027-r0tl01kq	1826	32	nozzle	nozzle	NN
cord-010027-r0tl01kq	1826	33	.	.	.
cord-010027-r0tl01kq	1827	1	An	an	DT
cord-010027-r0tl01kq	1827	2	optical	optical	JJ
cord-010027-r0tl01kq	1827	3	detection	detection	NN
cord-010027-r0tl01kq	1827	4	mechanism	mechanism	NN
cord-010027-r0tl01kq	1827	5	determined	determine	VBD
cord-010027-r0tl01kq	1827	6	the	the	DT
cord-010027-r0tl01kq	1827	7	presence	presence	NN
cord-010027-r0tl01kq	1827	8	of	of	IN
cord-010027-r0tl01kq	1827	9	single	single	JJ
cord-010027-r0tl01kq	1827	10	,	,	,
cord-010027-r0tl01kq	1827	11	fluorescent	fluorescent	NN
cord-010027-r0tl01kq	1827	12	cells	cell	NNS
cord-010027-r0tl01kq	1827	13	within	within	IN
cord-010027-r0tl01kq	1827	14	the	the	DT
cord-010027-r0tl01kq	1827	15	selected	select	VBN
cord-010027-r0tl01kq	1827	16	region	region	NN
cord-010027-r0tl01kq	1827	17	of	of	IN
cord-010027-r0tl01kq	1827	18	interest	interest	NN
cord-010027-r0tl01kq	1827	19	close	close	RB
cord-010027-r0tl01kq	1827	20	to	to	IN
cord-010027-r0tl01kq	1827	21	the	the	DT
cord-010027-r0tl01kq	1827	22	chip	chip	NN
cord-010027-r0tl01kq	1827	23	exit	exit	NN
cord-010027-r0tl01kq	1827	24	nozzle	nozzle	NN
cord-010027-r0tl01kq	1827	25	.	.	.
cord-010027-r0tl01kq	1828	1	A	a	DT
cord-010027-r0tl01kq	1828	2	sorting	sorting	NN
cord-010027-r0tl01kq	1828	3	algorithm	algorithm	NN
cord-010027-r0tl01kq	1828	4	ensured	ensure	VBD
cord-010027-r0tl01kq	1828	5	that	that	IN
cord-010027-r0tl01kq	1828	6	only	only	RB
cord-010027-r0tl01kq	1828	7	droplets	droplet	NNS
cord-010027-r0tl01kq	1828	8	containing	contain	VBG
cord-010027-r0tl01kq	1828	9	the	the	DT
cord-010027-r0tl01kq	1828	10	single	single	JJ
cord-010027-r0tl01kq	1828	11	cells	cell	NNS
cord-010027-r0tl01kq	1828	12	of	of	IN
cord-010027-r0tl01kq	1828	13	interest	interest	NN
cord-010027-r0tl01kq	1828	14	were	be	VBD
cord-010027-r0tl01kq	1828	15	selected	select	VBN
cord-010027-r0tl01kq	1828	16	for	for	IN
cord-010027-r0tl01kq	1828	17	printing	print	VBG
cord-010027-r0tl01kq	1828	18	to	to	IN
cord-010027-r0tl01kq	1828	19	the	the	DT
cord-010027-r0tl01kq	1828	20	prescribed	prescribed	JJ
cord-010027-r0tl01kq	1828	21	location	location	NN
cord-010027-r0tl01kq	1828	22	and	and	CC
cord-010027-r0tl01kq	1828	23	user	user	NN
cord-010027-r0tl01kq	1828	24	-	-	HYPH
cord-010027-r0tl01kq	1828	25	chosen	choose	VBN
cord-010027-r0tl01kq	1828	26	substrate	substrate	NN
cord-010027-r0tl01kq	1828	27	.	.	.
cord-010027-r0tl01kq	1829	1	Results	result	NNS
cord-010027-r0tl01kq	1829	2	:	:	:
cord-010027-r0tl01kq	1830	1	Fluorescently	Fluorescently	NNP
cord-010027-r0tl01kq	1830	2	labelled	label	VBD
cord-010027-r0tl01kq	1830	3	HPV16	hpv16	NN
cord-010027-r0tl01kq	1831	1	CaSki	caski	JJ
cord-010027-r0tl01kq	1831	2	cervical	cervical	JJ
cord-010027-r0tl01kq	1831	3	cells	cell	NNS
cord-010027-r0tl01kq	1831	4	were	be	VBD
cord-010027-r0tl01kq	1831	5	spiked	spike	VBN
cord-010027-r0tl01kq	1831	6	into	into	IN
cord-010027-r0tl01kq	1831	7	a	a	DT
cord-010027-r0tl01kq	1831	8	cervical	cervical	JJ
cord-010027-r0tl01kq	1831	9	liquid	liquid	NN
cord-010027-r0tl01kq	1831	10	based	base	VBN
cord-010027-r0tl01kq	1831	11	cytology	cytology	NN
cord-010027-r0tl01kq	1831	12	sample	sample	NN
cord-010027-r0tl01kq	1831	13	and	and	CC
cord-010027-r0tl01kq	1831	14	printed	print	VBN
cord-010027-r0tl01kq	1831	15	onto	onto	IN
cord-010027-r0tl01kq	1831	16	a	a	DT
cord-010027-r0tl01kq	1831	17	glass	glass	NN
cord-010027-r0tl01kq	1831	18	slide	slide	NN
cord-010027-r0tl01kq	1831	19	using	use	VBG
cord-010027-r0tl01kq	1831	20	the	the	DT
cord-010027-r0tl01kq	1831	21	SCM	SCM	NNP
cord-010027-r0tl01kq	1831	22	.	.	.
cord-010027-r0tl01kq	1832	1	Undifferentiated	Undifferentiated	NNP
cord-010027-r0tl01kq	1832	2	NTera2	NTera2	NNP
cord-010027-r0tl01kq	1832	3	human	human	JJ
cord-010027-r0tl01kq	1832	4	embryonal	embryonal	JJ
cord-010027-r0tl01kq	1832	5	cancer	cancer	NN
cord-010027-r0tl01kq	1832	6	stem	stem	NN
cord-010027-r0tl01kq	1832	7	cells	cell	NNS
cord-010027-r0tl01kq	1832	8	were	be	VBD
cord-010027-r0tl01kq	1832	9	isolated	isolate	VBN
cord-010027-r0tl01kq	1832	10	from	from	IN
cord-010027-r0tl01kq	1832	11	a	a	DT
cord-010027-r0tl01kq	1832	12	mixture	mixture	NN
cord-010027-r0tl01kq	1832	13	of	of	IN
cord-010027-r0tl01kq	1832	14	differentiated	differentiated	JJ
cord-010027-r0tl01kq	1832	15	and	and	CC
cord-010027-r0tl01kq	1832	16	undifferentiated	undifferentiated	JJ
cord-010027-r0tl01kq	1832	17	cells	cell	NNS
cord-010027-r0tl01kq	1832	18	based	base	VBN
cord-010027-r0tl01kq	1832	19	on	on	IN
cord-010027-r0tl01kq	1832	20	fluorescent	fluorescent	NN
cord-010027-r0tl01kq	1832	21	tagging	tagging	NN
cord-010027-r0tl01kq	1832	22	of	of	IN
cord-010027-r0tl01kq	1832	23	the	the	DT
cord-010027-r0tl01kq	1832	24	cell	cell	NN
cord-010027-r0tl01kq	1832	25	surface	surface	NN
cord-010027-r0tl01kq	1832	26	receptor	receptor	NN
cord-010027-r0tl01kq	1832	27	,	,	,
cord-010027-r0tl01kq	1832	28	stagespecific	stagespecific	NNP
cord-010027-r0tl01kq	1832	29	embryonal	embryonal	NNP
cord-010027-r0tl01kq	1832	30	antigen	antigen	NNP
cord-010027-r0tl01kq	1832	31	4	4	CD
cord-010027-r0tl01kq	1832	32	(	(	-LRB-
cord-010027-r0tl01kq	1832	33	SSEA4	SSEA4	NNP
cord-010027-r0tl01kq	1832	34	)	)	-RRB-
cord-010027-r0tl01kq	1832	35	.	.	.
cord-010027-r0tl01kq	1833	1	The	the	DT
cord-010027-r0tl01kq	1833	2	thyroid	thyroid	JJ
cord-010027-r0tl01kq	1833	3	stimulating	stimulate	VBG
cord-010027-r0tl01kq	1833	4	hormone	hormone	NN
cord-010027-r0tl01kq	1833	5	receptor	receptor	NN
cord-010027-r0tl01kq	1833	6	(	(	-LRB-
cord-010027-r0tl01kq	1833	7	TSHR	TSHR	NNP
cord-010027-r0tl01kq	1833	8	)	)	-RRB-
cord-010027-r0tl01kq	1833	9	was	be	VBD
cord-010027-r0tl01kq	1833	10	expressed	express	VBN
cord-010027-r0tl01kq	1833	11	in	in	IN
cord-010027-r0tl01kq	1833	12	anaplastic	anaplastic	JJ
cord-010027-r0tl01kq	1833	13	V600E	V600E	NNS
cord-010027-r0tl01kq	1833	14	mutated	mutate	VBN
cord-010027-r0tl01kq	1833	15	thyroid	thyroid	JJ
cord-010027-r0tl01kq	1833	16	cancer	cancer	NN
cord-010027-r0tl01kq	1833	17	cell	cell	NN
cord-010027-r0tl01kq	1833	18	lines	line	NNS
cord-010027-r0tl01kq	1833	19	that	that	WDT
cord-010027-r0tl01kq	1833	20	were	be	VBD
cord-010027-r0tl01kq	1833	21	treated	treat	VBN
cord-010027-r0tl01kq	1833	22	with	with	IN
cord-010027-r0tl01kq	1833	23	the	the	DT
cord-010027-r0tl01kq	1833	24	MEK	MEK	NNP
cord-010027-r0tl01kq	1833	25	inhibitor	inhibitor	NN
cord-010027-r0tl01kq	1833	26	PD0325901	PD0325901	NNP
cord-010027-r0tl01kq	1833	27	.	.	.
cord-010027-r0tl01kq	1834	1	Treated	treat	VBN
cord-010027-r0tl01kq	1834	2	cells	cell	NNS
cord-010027-r0tl01kq	1834	3	were	be	VBD
cord-010027-r0tl01kq	1834	4	isolated	isolate	VBN
cord-010027-r0tl01kq	1834	5	using	use	VBG
cord-010027-r0tl01kq	1834	6	the	the	DT
cord-010027-r0tl01kq	1834	7	SCM	SCM	NNP
cord-010027-r0tl01kq	1834	8	.	.	.
cord-010027-r0tl01kq	1835	1	The	the	DT
cord-010027-r0tl01kq	1835	2	SCM	SCM	NNP
cord-010027-r0tl01kq	1835	3	PASCA	PASCA	NNP
cord-010027-r0tl01kq	1835	4	technology	technology	NN
cord-010027-r0tl01kq	1835	5	allows	allow	VBZ
cord-010027-r0tl01kq	1835	6	isolation	isolation	NN
cord-010027-r0tl01kq	1835	7	of	of	IN
cord-010027-r0tl01kq	1835	8	single	single	JJ
cord-010027-r0tl01kq	1835	9	cells	cell	NNS
cord-010027-r0tl01kq	1835	10	from	from	IN
cord-010027-r0tl01kq	1835	11	heterogeneous	heterogeneous	JJ
cord-010027-r0tl01kq	1835	12	populations	population	NNS
cord-010027-r0tl01kq	1835	13	of	of	IN
cord-010027-r0tl01kq	1835	14	cells	cell	NNS
cord-010027-r0tl01kq	1835	15	and	and	CC
cord-010027-r0tl01kq	1835	16	clinical	clinical	JJ
cord-010027-r0tl01kq	1835	17	samples	sample	NNS
cord-010027-r0tl01kq	1835	18	for	for	IN
cord-010027-r0tl01kq	1835	19	downstream	downstream	JJ
cord-010027-r0tl01kq	1835	20	analysis	analysis	NN
cord-010027-r0tl01kq	1835	21	at	at	IN
cord-010027-r0tl01kq	1835	22	a	a	DT
cord-010027-r0tl01kq	1835	23	single	single	JJ
cord-010027-r0tl01kq	1835	24	cell	cell	NN
cord-010027-r0tl01kq	1835	25	level	level	NN
cord-010027-r0tl01kq	1835	26	.	.	.
cord-010027-r0tl01kq	1836	1	This	this	DT
cord-010027-r0tl01kq	1836	2	study	study	NN
cord-010027-r0tl01kq	1836	3	aims	aim	VBZ
cord-010027-r0tl01kq	1836	4	at	at	IN
cord-010027-r0tl01kq	1836	5	quantifying	quantify	VBG
cord-010027-r0tl01kq	1836	6	immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1836	7	(	(	-LRB-
cord-010027-r0tl01kq	1836	8	IHC	IHC	NNP
cord-010027-r0tl01kq	1836	9	)	)	-RRB-
cord-010027-r0tl01kq	1836	10	stained	stain	VBN
cord-010027-r0tl01kq	1836	11	human	human	JJ
cord-010027-r0tl01kq	1836	12	cell	cell	NN
cord-010027-r0tl01kq	1836	13	lines	line	NNS
cord-010027-r0tl01kq	1836	14	for	for	IN
cord-010027-r0tl01kq	1836	15	protein	protein	NN
cord-010027-r0tl01kq	1836	16	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1836	17	by	by	IN
cord-010027-r0tl01kq	1836	18	manual	manual	JJ
cord-010027-r0tl01kq	1836	19	pathologist	pathologist	NN
cord-010027-r0tl01kq	1836	20	review	review	NN
cord-010027-r0tl01kq	1836	21	.	.	.
cord-010027-r0tl01kq	1837	1	Staining	staining	NN
cord-010027-r0tl01kq	1837	2	analyses	analysis	NNS
cord-010027-r0tl01kq	1837	3	are	be	VBP
cord-010027-r0tl01kq	1837	4	used	use	VBN
cord-010027-r0tl01kq	1837	5	to	to	TO
cord-010027-r0tl01kq	1837	6	calibrate	calibrate	VB
cord-010027-r0tl01kq	1837	7	tissue	tissue	NN
cord-010027-r0tl01kq	1837	8	microarrays	microarray	NNS
cord-010027-r0tl01kq	1837	9	of	of	IN
cord-010027-r0tl01kq	1837	10	tumour	tumour	NN
cord-010027-r0tl01kq	1837	11	cores	core	NNS
cord-010027-r0tl01kq	1837	12	,	,	,
cord-010027-r0tl01kq	1837	13	against	against	IN
cord-010027-r0tl01kq	1837	14	quantitative	quantitative	JJ
cord-010027-r0tl01kq	1837	15	protein	protein	NN
cord-010027-r0tl01kq	1837	16	concentration	concentration	NN
cord-010027-r0tl01kq	1837	17	allowing	allow	VBG
cord-010027-r0tl01kq	1837	18	a	a	DT
cord-010027-r0tl01kq	1837	19	systems	system	NNS
cord-010027-r0tl01kq	1837	20	-	-	HYPH
cord-010027-r0tl01kq	1837	21	based	base	VBN
cord-010027-r0tl01kq	1837	22	data	datum	NNS
cord-010027-r0tl01kq	1837	23	analysis	analysis	NN
cord-010027-r0tl01kq	1837	24	.	.	.
cord-010027-r0tl01kq	1838	1	As	as	IN
cord-010027-r0tl01kq	1838	2	a	a	DT
cord-010027-r0tl01kq	1838	3	proof	proof	NN
cord-010027-r0tl01kq	1838	4	of	of	IN
cord-010027-r0tl01kq	1838	5	concept	concept	NN
cord-010027-r0tl01kq	1838	6	,	,	,
cord-010027-r0tl01kq	1838	7	FFPE	FFPE	NNP
cord-010027-r0tl01kq	1838	8	human	human	JJ
cord-010027-r0tl01kq	1838	9	cell	cell	NN
cord-010027-r0tl01kq	1838	10	line	line	NN
cord-010027-r0tl01kq	1838	11	pellets	pellet	NNS
cord-010027-r0tl01kq	1838	12	(	(	-LRB-
cord-010027-r0tl01kq	1838	13	n=13	n=13	NNP
cord-010027-r0tl01kq	1838	14	)	)	-RRB-
cord-010027-r0tl01kq	1838	15	were	be	VBD
cord-010027-r0tl01kq	1838	16	IHC	IHC	NNP
cord-010027-r0tl01kq	1838	17	stained	stain	VBN
cord-010027-r0tl01kq	1838	18	for	for	IN
cord-010027-r0tl01kq	1838	19	Smac	Smac	NNP
cord-010027-r0tl01kq	1838	20	protein	protein	NN
cord-010027-r0tl01kq	1838	21	and	and	CC
cord-010027-r0tl01kq	1838	22	analysed	analyse	VBD
cord-010027-r0tl01kq	1838	23	using	use	VBG
cord-010027-r0tl01kq	1838	24	Aperio	Aperio	NNP
cord-010027-r0tl01kq	1838	25	image	image	NN
cord-010027-r0tl01kq	1838	26	analysis	analysis	NN
cord-010027-r0tl01kq	1838	27	software	software	NN
cord-010027-r0tl01kq	1838	28	.	.	.
cord-010027-r0tl01kq	1839	1	Staining	stain	VBG
cord-010027-r0tl01kq	1839	2	quantification	quantification	NN
cord-010027-r0tl01kq	1839	3	manually	manually	RB
cord-010027-r0tl01kq	1839	4	performed	perform	VBN
cord-010027-r0tl01kq	1839	5	by	by	IN
cord-010027-r0tl01kq	1839	6	pathologists	pathologist	NNS
cord-010027-r0tl01kq	1839	7	provided	provide	VBD
cord-010027-r0tl01kq	1839	8	parameters	parameter	NNS
cord-010027-r0tl01kq	1839	9	including	include	VBG
cord-010027-r0tl01kq	1839	10	average	average	JJ
cord-010027-r0tl01kq	1839	11	staining	stain	VBG
cord-010027-r0tl01kq	1839	12	intensity	intensity	NN
cord-010027-r0tl01kq	1839	13	,	,	,
cord-010027-r0tl01kq	1839	14	percent	percent	NN
cord-010027-r0tl01kq	1839	15	total	total	JJ
cord-010027-r0tl01kq	1839	16	cell	cell	NN
cord-010027-r0tl01kq	1839	17	positivity	positivity	NN
cord-010027-r0tl01kq	1839	18	and	and	CC
cord-010027-r0tl01kq	1839	19	H	h	NN
cord-010027-r0tl01kq	1839	20	-	-	HYPH
cord-010027-r0tl01kq	1839	21	score	score	NN
cord-010027-r0tl01kq	1839	22	.	.	.
cord-010027-r0tl01kq	1840	1	These	these	DT
cord-010027-r0tl01kq	1840	2	data	datum	NNS
cord-010027-r0tl01kq	1840	3	were	be	VBD
cord-010027-r0tl01kq	1840	4	enriched	enrich	VBN
cord-010027-r0tl01kq	1840	5	by	by	IN
cord-010027-r0tl01kq	1840	6	qualitative	qualitative	JJ
cord-010027-r0tl01kq	1840	7	parameters	parameter	NNS
cord-010027-r0tl01kq	1840	8	pointing	point	VBG
cord-010027-r0tl01kq	1840	9	out	out	RP
cord-010027-r0tl01kq	1840	10	possible	possible	JJ
cord-010027-r0tl01kq	1840	11	histological	histological	JJ
cord-010027-r0tl01kq	1840	12	artefacts	artefact	NNS
cord-010027-r0tl01kq	1840	13	.	.	.
cord-010027-r0tl01kq	1841	1	A	a	DT
cord-010027-r0tl01kq	1841	2	calibration	calibration	NN
cord-010027-r0tl01kq	1841	3	curve	curve	NN
cord-010027-r0tl01kq	1841	4	was	be	VBD
cord-010027-r0tl01kq	1841	5	plotted	plot	VBN
cord-010027-r0tl01kq	1841	6	using	use	VBG
cord-010027-r0tl01kq	1841	7	H	h	NN
cord-010027-r0tl01kq	1841	8	-	-	HYPH
cord-010027-r0tl01kq	1841	9	score	score	NN
cord-010027-r0tl01kq	1841	10	data	datum	NNS
cord-010027-r0tl01kq	1841	11	and	and	CC
cord-010027-r0tl01kq	1841	12	protein	protein	NN
cord-010027-r0tl01kq	1841	13	concentrations	concentration	NNS
cord-010027-r0tl01kq	1841	14	,	,	,
cord-010027-r0tl01kq	1841	15	previously	previously	RB
cord-010027-r0tl01kq	1841	16	determined	determine	VBN
cord-010027-r0tl01kq	1841	17	by	by	IN
cord-010027-r0tl01kq	1841	18	Western	western	JJ
cord-010027-r0tl01kq	1841	19	blotting	blotting	NN
cord-010027-r0tl01kq	1841	20	.	.	.
cord-010027-r0tl01kq	1842	1	The	the	DT
cord-010027-r0tl01kq	1842	2	panel	panel	NN
cord-010027-r0tl01kq	1842	3	of	of	IN
cord-010027-r0tl01kq	1842	4	cell	cell	NN
cord-010027-r0tl01kq	1842	5	lines	line	NNS
cord-010027-r0tl01kq	1842	6	provided	provide	VBD
cord-010027-r0tl01kq	1842	7	a	a	DT
cord-010027-r0tl01kq	1842	8	range	range	NN
cord-010027-r0tl01kq	1842	9	of	of	IN
cord-010027-r0tl01kq	1842	10	strong	strong	JJ
cord-010027-r0tl01kq	1842	11	and	and	CC
cord-010027-r0tl01kq	1842	12	weak	weak	JJ
cord-010027-r0tl01kq	1842	13	/	/	SYM
cord-010027-r0tl01kq	1842	14	absent	absent	JJ
cord-010027-r0tl01kq	1842	15	IHC	IHC	NNP
cord-010027-r0tl01kq	1842	16	staining	staining	NN
cord-010027-r0tl01kq	1842	17	using	use	VBG
cord-010027-r0tl01kq	1842	18	a	a	DT
cord-010027-r0tl01kq	1842	19	highly	highly	RB
cord-010027-r0tl01kq	1842	20	specific	specific	JJ
cord-010027-r0tl01kq	1842	21	Smac	Smac	NNP
cord-010027-r0tl01kq	1842	22	antibody	antibody	NN
cord-010027-r0tl01kq	1842	23	.	.	.
cord-010027-r0tl01kq	1843	1	The	the	DT
cord-010027-r0tl01kq	1843	2	calibration	calibration	NN
cord-010027-r0tl01kq	1843	3	curve	curve	NN
cord-010027-r0tl01kq	1843	4	showed	show	VBD
cord-010027-r0tl01kq	1843	5	a	a	DT
cord-010027-r0tl01kq	1843	6	strong	strong	JJ
cord-010027-r0tl01kq	1843	7	correlation	correlation	NN
cord-010027-r0tl01kq	1843	8	between	between	IN
cord-010027-r0tl01kq	1843	9	absolute	absolute	JJ
cord-010027-r0tl01kq	1843	10	protein	protein	NN
cord-010027-r0tl01kq	1843	11	concentrations	concentration	NNS
cord-010027-r0tl01kq	1843	12	and	and	CC
cord-010027-r0tl01kq	1843	13	manual	manual	JJ
cord-010027-r0tl01kq	1843	14	H	h	NN
cord-010027-r0tl01kq	1843	15	-	-	HYPH
cord-010027-r0tl01kq	1843	16	scores	score	NNS
cord-010027-r0tl01kq	1843	17	.	.	.
cord-010027-r0tl01kq	1844	1	Expression	expression	NN
cord-010027-r0tl01kq	1844	2	amounts	amount	VBZ
cord-010027-r0tl01kq	1844	3	in	in	IN
cord-010027-r0tl01kq	1844	4	cell	cell	NN
cord-010027-r0tl01kq	1844	5	lines	line	NNS
cord-010027-r0tl01kq	1844	6	correlate	correlate	VBP
cord-010027-r0tl01kq	1844	7	with	with	IN
cord-010027-r0tl01kq	1844	8	IHC	IHC	NNP
cord-010027-r0tl01kq	1844	9	staining	stain	VBG
cord-010027-r0tl01kq	1844	10	intensities	intensity	NNS
cord-010027-r0tl01kq	1844	11	determined	determine	VBN
cord-010027-r0tl01kq	1844	12	by	by	IN
cord-010027-r0tl01kq	1844	13	pathologist	pathologist	NN
cord-010027-r0tl01kq	1844	14	review	review	NN
cord-010027-r0tl01kq	1844	15	.	.	.
cord-010027-r0tl01kq	1845	1	The	the	DT
cord-010027-r0tl01kq	1845	2	linear	linear	JJ
cord-010027-r0tl01kq	1845	3	correlation	correlation	NN
cord-010027-r0tl01kq	1845	4	between	between	IN
cord-010027-r0tl01kq	1845	5	manual	manual	JJ
cord-010027-r0tl01kq	1845	6	H	h	NN
cord-010027-r0tl01kq	1845	7	-	-	HYPH
cord-010027-r0tl01kq	1845	8	score	score	NN
cord-010027-r0tl01kq	1845	9	and	and	CC
cord-010027-r0tl01kq	1845	10	absolute	absolute	JJ
cord-010027-r0tl01kq	1845	11	protein	protein	NN
cord-010027-r0tl01kq	1845	12	values	value	NNS
cord-010027-r0tl01kq	1845	13	provides	provide	VBZ
cord-010027-r0tl01kq	1845	14	an	an	DT
cord-010027-r0tl01kq	1845	15	avenue	avenue	NN
cord-010027-r0tl01kq	1845	16	to	to	TO
cord-010027-r0tl01kq	1845	17	indirectly	indirectly	RB
cord-010027-r0tl01kq	1845	18	determine	determine	VB
cord-010027-r0tl01kq	1845	19	protein	protein	NN
cord-010027-r0tl01kq	1845	20	expression	expression	NN
cord-010027-r0tl01kq	1845	21	.	.	.
cord-010027-r0tl01kq	1846	1	Further	further	JJ
cord-010027-r0tl01kq	1846	2	analysis	analysis	NN
cord-010027-r0tl01kq	1846	3	will	will	MD
cord-010027-r0tl01kq	1846	4	be	be	VB
cord-010027-r0tl01kq	1846	5	performed	perform	VBN
cord-010027-r0tl01kq	1846	6	on	on	IN
cord-010027-r0tl01kq	1846	7	additional	additional	JJ
cord-010027-r0tl01kq	1846	8	antigens	antigen	NNS
cord-010027-r0tl01kq	1846	9	and	and	CC
cord-010027-r0tl01kq	1846	10	analysis	analysis	NN
cord-010027-r0tl01kq	1846	11	outcomes	outcome	NNS
cord-010027-r0tl01kq	1846	12	will	will	MD
cord-010027-r0tl01kq	1846	13	be	be	VB
cord-010027-r0tl01kq	1846	14	then	then	RB
cord-010027-r0tl01kq	1846	15	compared	compare	VBN
cord-010027-r0tl01kq	1846	16	to	to	IN
cord-010027-r0tl01kq	1846	17	digital	digital	JJ
cord-010027-r0tl01kq	1846	18	results	result	NNS
cord-010027-r0tl01kq	1846	19	.	.	.
cord-010027-r0tl01kq	1847	1	This	this	DT
cord-010027-r0tl01kq	1847	2	data	datum	NNS
cord-010027-r0tl01kq	1847	3	will	will	MD
cord-010027-r0tl01kq	1847	4	provide	provide	VB
cord-010027-r0tl01kq	1847	5	the	the	DT
cord-010027-r0tl01kq	1847	6	basis	basis	NN
cord-010027-r0tl01kq	1847	7	for	for	IN
cord-010027-r0tl01kq	1847	8	deterministic	deterministic	JJ
cord-010027-r0tl01kq	1847	9	systems	system	NNS
cord-010027-r0tl01kq	1847	10	-	-	HYPH
cord-010027-r0tl01kq	1847	11	biological	biological	JJ
cord-010027-r0tl01kq	1847	12	data	data	NN
cord-010027-r0tl01kq	1847	13	analysis	analysis	NN
cord-010027-r0tl01kq	1847	14	approaches	approach	NNS
cord-010027-r0tl01kq	1847	15	.	.	.
cord-010027-r0tl01kq	1848	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1848	2	of	of	IN
cord-010027-r0tl01kq	1848	3	the	the	DT
cord-010027-r0tl01kq	1848	4	Study	study	NN
cord-010027-r0tl01kq	1848	5	:	:	:
cord-010027-r0tl01kq	1848	6	'	'	``
cord-010027-r0tl01kq	1848	7	Lean	Lean	NNP
cord-010027-r0tl01kq	1848	8	'	'	''
cord-010027-r0tl01kq	1848	9	is	be	VBZ
cord-010027-r0tl01kq	1848	10	a	a	DT
cord-010027-r0tl01kq	1848	11	management	management	NN
cord-010027-r0tl01kq	1848	12	framework	framework	NN
cord-010027-r0tl01kq	1848	13	for	for	IN
cord-010027-r0tl01kq	1848	14	maximising	maximise	VBG
cord-010027-r0tl01kq	1848	15	value	value	NN
cord-010027-r0tl01kq	1848	16	and	and	CC
cord-010027-r0tl01kq	1848	17	minimising	minimise	VBG
cord-010027-r0tl01kq	1848	18	waste	waste	NN
cord-010027-r0tl01kq	1848	19	.	.	.
cord-010027-r0tl01kq	1849	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1849	2	originated	originate	VBD
cord-010027-r0tl01kq	1849	3	in	in	IN
cord-010027-r0tl01kq	1849	4	the	the	DT
cord-010027-r0tl01kq	1849	5	automotive	automotive	JJ
cord-010027-r0tl01kq	1849	6	manufacturing	manufacturing	NN
cord-010027-r0tl01kq	1849	7	industry	industry	NN
cord-010027-r0tl01kq	1849	8	and	and	CC
cord-010027-r0tl01kq	1849	9	has	have	VBZ
cord-010027-r0tl01kq	1849	10	been	be	VBN
cord-010027-r0tl01kq	1849	11	utilised	utilise	VBN
cord-010027-r0tl01kq	1849	12	successfully	successfully	RB
cord-010027-r0tl01kq	1849	13	in	in	IN
cord-010027-r0tl01kq	1849	14	non	non	JJ
cord-010027-r0tl01kq	1849	15	-	-	JJ
cord-010027-r0tl01kq	1849	16	manufacturing	manufacturing	JJ
cord-010027-r0tl01kq	1849	17	processes	process	NNS
cord-010027-r0tl01kq	1849	18	.	.	.
cord-010027-r0tl01kq	1850	1	One	one	CD
cord-010027-r0tl01kq	1850	2	such	such	JJ
cord-010027-r0tl01kq	1850	3	application	application	NN
cord-010027-r0tl01kq	1850	4	in	in	IN
cord-010027-r0tl01kq	1850	5	our	-PRON-	PRP$
cord-010027-r0tl01kq	1850	6	department	department	NN
cord-010027-r0tl01kq	1850	7	was	be	VBD
cord-010027-r0tl01kq	1850	8	the	the	DT
cord-010027-r0tl01kq	1850	9	'	'	``
cord-010027-r0tl01kq	1850	10	leaning	leaning	NN
cord-010027-r0tl01kq	1850	11	'	'	''
cord-010027-r0tl01kq	1850	12	of	of	IN
cord-010027-r0tl01kq	1850	13	the	the	DT
cord-010027-r0tl01kq	1850	14	molecular	molecular	JJ
cord-010027-r0tl01kq	1850	15	test	test	NN
cord-010027-r0tl01kq	1850	16	requesting	request	VBG
cord-010027-r0tl01kq	1850	17	process	process	NN
cord-010027-r0tl01kq	1850	18	using	use	VBG
cord-010027-r0tl01kq	1850	19	a	a	DT
cord-010027-r0tl01kq	1850	20	smart	smart	JJ
cord-010027-r0tl01kq	1850	21	-	-	HYPH
cord-010027-r0tl01kq	1850	22	phone	phone	NN
cord-010027-r0tl01kq	1850	23	app	app	NN
cord-010027-r0tl01kq	1850	24	.	.	.
cord-010027-r0tl01kq	1851	1	This	this	DT
cord-010027-r0tl01kq	1851	2	study	study	NN
cord-010027-r0tl01kq	1851	3	will	will	MD
cord-010027-r0tl01kq	1851	4	look	look	VB
cord-010027-r0tl01kq	1851	5	at	at	IN
cord-010027-r0tl01kq	1851	6	the	the	DT
cord-010027-r0tl01kq	1851	7	potential	potential	JJ
cord-010027-r0tl01kq	1851	8	utility	utility	NN
cord-010027-r0tl01kq	1851	9	of	of	IN
cord-010027-r0tl01kq	1851	10	this	this	DT
cord-010027-r0tl01kq	1851	11	application	application	NN
cord-010027-r0tl01kq	1851	12	within	within	IN
cord-010027-r0tl01kq	1851	13	the	the	DT
cord-010027-r0tl01kq	1851	14	National	National	NNP
cord-010027-r0tl01kq	1851	15	Health	Health	NNP
cord-010027-r0tl01kq	1851	16	Service	Service	NNP
cord-010027-r0tl01kq	1851	17	(	(	-LRB-
cord-010027-r0tl01kq	1851	18	NHS	NHS	NNP
cord-010027-r0tl01kq	1851	19	)	)	-RRB-
cord-010027-r0tl01kq	1851	20	,	,	,
cord-010027-r0tl01kq	1851	21	wherein	wherein	WRB
cord-010027-r0tl01kq	1851	22	approximately	approximately	RB
cord-010027-r0tl01kq	1851	23	twenty	twenty	CD
cord-010027-r0tl01kq	1851	24	different	different	JJ
cord-010027-r0tl01kq	1851	25	molecular	molecular	JJ
cord-010027-r0tl01kq	1851	26	test	test	NN
cord-010027-r0tl01kq	1851	27	request	request	NN
cord-010027-r0tl01kq	1851	28	forms	form	NNS
cord-010027-r0tl01kq	1851	29	are	be	VBP
cord-010027-r0tl01kq	1851	30	currently	currently	RB
cord-010027-r0tl01kq	1851	31	in	in	IN
cord-010027-r0tl01kq	1851	32	use	use	NN
cord-010027-r0tl01kq	1851	33	.	.	.
cord-010027-r0tl01kq	1852	1	A	a	DT
cord-010027-r0tl01kq	1852	2	mobile	mobile	JJ
cord-010027-r0tl01kq	1852	3	application	application	NN
cord-010027-r0tl01kq	1852	4	to	to	TO
cord-010027-r0tl01kq	1852	5	facilitate	facilitate	VB
cord-010027-r0tl01kq	1852	6	molecular	molecular	JJ
cord-010027-r0tl01kq	1852	7	test	test	NN
cord-010027-r0tl01kq	1852	8	requesting	request	VBG
cord-010027-r0tl01kq	1852	9	was	be	VBD
cord-010027-r0tl01kq	1852	10	developed	develop	VBN
cord-010027-r0tl01kq	1852	11	using	use	VBG
cord-010027-r0tl01kq	1852	12	Xcode	Xcode	NNP
cord-010027-r0tl01kq	1852	13	and	and	CC
cord-010027-r0tl01kq	1852	14	the	the	DT
cord-010027-r0tl01kq	1852	15	objective	objective	JJ
cord-010027-r0tl01kq	1852	16	C	C	NNP
cord-010027-r0tl01kq	1852	17	programming	programming	NN
cord-010027-r0tl01kq	1852	18	language	language	NN
cord-010027-r0tl01kq	1852	19	.	.	.
cord-010027-r0tl01kq	1853	1	The	the	DT
cord-010027-r0tl01kq	1853	2	application	application	NN
cord-010027-r0tl01kq	1853	3	was	be	VBD
cord-010027-r0tl01kq	1853	4	built	build	VBN
cord-010027-r0tl01kq	1853	5	around	around	IN
cord-010027-r0tl01kq	1853	6	an	an	DT
cord-010027-r0tl01kq	1853	7	email	email	NN
cord-010027-r0tl01kq	1853	8	based	base	VBN
cord-010027-r0tl01kq	1853	9	system	system	NN
cord-010027-r0tl01kq	1853	10	.	.	.
cord-010027-r0tl01kq	1854	1	Patient	patient	JJ
cord-010027-r0tl01kq	1854	2	anonymity	anonymity	NN
cord-010027-r0tl01kq	1854	3	was	be	VBD
cord-010027-r0tl01kq	1854	4	paramount	paramount	JJ
cord-010027-r0tl01kq	1854	5	in	in	IN
cord-010027-r0tl01kq	1854	6	the	the	DT
cord-010027-r0tl01kq	1854	7	design	design	NN
cord-010027-r0tl01kq	1854	8	;	;	:
cord-010027-r0tl01kq	1854	9	NHS	NHS	NNP
cord-010027-r0tl01kq	1854	10	numbers	number	NNS
cord-010027-r0tl01kq	1854	11	are	be	VBP
cord-010027-r0tl01kq	1854	12	used	use	VBN
cord-010027-r0tl01kq	1854	13	as	as	IN
cord-010027-r0tl01kq	1854	14	identifiers	identifier	NNS
cord-010027-r0tl01kq	1854	15	.	.	.
cord-010027-r0tl01kq	1855	1	The	the	DT
cord-010027-r0tl01kq	1855	2	application	application	NN
cord-010027-r0tl01kq	1855	3	generates	generate	VBZ
cord-010027-r0tl01kq	1855	4	a	a	DT
cord-010027-r0tl01kq	1855	5	molecular	molecular	JJ
cord-010027-r0tl01kq	1855	6	test	test	NN
cord-010027-r0tl01kq	1855	7	request	request	NN
cord-010027-r0tl01kq	1855	8	form	form	NN
cord-010027-r0tl01kq	1855	9	and	and	CC
cord-010027-r0tl01kq	1855	10	can	can	MD
cord-010027-r0tl01kq	1855	11	also	also	RB
cord-010027-r0tl01kq	1855	12	generate	generate	VB
cord-010027-r0tl01kq	1855	13	a	a	DT
cord-010027-r0tl01kq	1855	14	national	national	JJ
cord-010027-r0tl01kq	1855	15	cancer	cancer	NN
cord-010027-r0tl01kq	1855	16	drugs	drug	NNS
cord-010027-r0tl01kq	1855	17	fund	fund	NN
cord-010027-r0tl01kq	1855	18	application	application	NN
cord-010027-r0tl01kq	1855	19	form	form	NN
cord-010027-r0tl01kq	1855	20	for	for	IN
cord-010027-r0tl01kq	1855	21	each	each	DT
cord-010027-r0tl01kq	1855	22	request	request	NN
cord-010027-r0tl01kq	1855	23	.	.	.
cord-010027-r0tl01kq	1856	1	Administrative	administrative	JJ
cord-010027-r0tl01kq	1856	2	staff	staff	NN
cord-010027-r0tl01kq	1856	3	use	use	NN
cord-010027-r0tl01kq	1856	4	colour	colour	NN
cord-010027-r0tl01kq	1856	5	coded	code	VBN
cord-010027-r0tl01kq	1856	6	flags	flag	NNS
cord-010027-r0tl01kq	1856	7	to	to	TO
cord-010027-r0tl01kq	1856	8	represent	represent	VB
cord-010027-r0tl01kq	1856	9	the	the	DT
cord-010027-r0tl01kq	1856	10	progress	progress	NN
cord-010027-r0tl01kq	1856	11	of	of	IN
cord-010027-r0tl01kq	1856	12	each	each	DT
cord-010027-r0tl01kq	1856	13	email	email	NN
cord-010027-r0tl01kq	1856	14	request	request	NN
cord-010027-r0tl01kq	1856	15	through	through	IN
cord-010027-r0tl01kq	1856	16	the	the	DT
cord-010027-r0tl01kq	1856	17	workflow	workflow	NN
cord-010027-r0tl01kq	1856	18	process	process	NN
cord-010027-r0tl01kq	1856	19	to	to	TO
cord-010027-r0tl01kq	1856	20	facilitate	facilitate	VB
cord-010027-r0tl01kq	1856	21	tracking	tracking	NN
cord-010027-r0tl01kq	1856	22	.	.	.
cord-010027-r0tl01kq	1857	1	The	the	DT
cord-010027-r0tl01kq	1857	2	app	app	NN
cord-010027-r0tl01kq	1857	3	reduced	reduce	VBD
cord-010027-r0tl01kq	1857	4	the	the	DT
cord-010027-r0tl01kq	1857	5	administrative	administrative	JJ
cord-010027-r0tl01kq	1857	6	staff	staff	NN
cord-010027-r0tl01kq	1857	7	workload	workload	NN
cord-010027-r0tl01kq	1857	8	by	by	IN
cord-010027-r0tl01kq	1857	9	reducing	reduce	VBG
cord-010027-r0tl01kq	1857	10	the	the	DT
cord-010027-r0tl01kq	1857	11	number	number	NN
cord-010027-r0tl01kq	1857	12	of	of	IN
cord-010027-r0tl01kq	1857	13	steps	step	NNS
cord-010027-r0tl01kq	1857	14	and	and	CC
cord-010027-r0tl01kq	1857	15	paperwork	paperwork	NN
cord-010027-r0tl01kq	1857	16	involved	involve	VBN
cord-010027-r0tl01kq	1857	17	in	in	IN
cord-010027-r0tl01kq	1857	18	the	the	DT
cord-010027-r0tl01kq	1857	19	molecular	molecular	JJ
cord-010027-r0tl01kq	1857	20	test	test	NN
cord-010027-r0tl01kq	1857	21	requesting	request	VBG
cord-010027-r0tl01kq	1857	22	process	process	NN
cord-010027-r0tl01kq	1857	23	.	.	.
cord-010027-r0tl01kq	1858	1	A	a	DT
cord-010027-r0tl01kq	1858	2	threefold	threefold	JJ
cord-010027-r0tl01kq	1858	3	reduction	reduction	NN
cord-010027-r0tl01kq	1858	4	in	in	IN
cord-010027-r0tl01kq	1858	5	time	time	NN
cord-010027-r0tl01kq	1858	6	taken	take	VBN
cord-010027-r0tl01kq	1858	7	by	by	IN
cord-010027-r0tl01kq	1858	8	clinicians	clinician	NNS
cord-010027-r0tl01kq	1858	9	to	to	TO
cord-010027-r0tl01kq	1858	10	request	request	VB
cord-010027-r0tl01kq	1858	11	molecular	molecular	JJ
cord-010027-r0tl01kq	1858	12	tests	test	NNS
cord-010027-r0tl01kq	1858	13	was	be	VBD
cord-010027-r0tl01kq	1858	14	noted	note	VBN
cord-010027-r0tl01kq	1858	15	.	.	.
cord-010027-r0tl01kq	1859	1	A	a	DT
cord-010027-r0tl01kq	1859	2	survey	survey	NN
cord-010027-r0tl01kq	1859	3	of	of	IN
cord-010027-r0tl01kq	1859	4	staff	staff	NN
cord-010027-r0tl01kq	1859	5	involved	involve	VBN
cord-010027-r0tl01kq	1859	6	with	with	IN
cord-010027-r0tl01kq	1859	7	molecular	molecular	JJ
cord-010027-r0tl01kq	1859	8	test	test	NN
cord-010027-r0tl01kq	1859	9	requesting	request	VBG
cord-010027-r0tl01kq	1859	10	revealed	reveal	VBD
cord-010027-r0tl01kq	1859	11	a	a	DT
cord-010027-r0tl01kq	1859	12	90	90	CD
cord-010027-r0tl01kq	1859	13	%	%	NN
cord-010027-r0tl01kq	1859	14	reduction	reduction	NN
cord-010027-r0tl01kq	1859	15	in	in	IN
cord-010027-r0tl01kq	1859	16	'	'	``
cord-010027-r0tl01kq	1859	17	lost	lose	VBN
cord-010027-r0tl01kq	1859	18	requests	request	NNS
cord-010027-r0tl01kq	1859	19	'	'	''
cord-010027-r0tl01kq	1859	20	after	after	IN
cord-010027-r0tl01kq	1859	21	the	the	DT
cord-010027-r0tl01kq	1859	22	introduction	introduction	NN
cord-010027-r0tl01kq	1859	23	of	of	IN
cord-010027-r0tl01kq	1859	24	the	the	DT
cord-010027-r0tl01kq	1859	25	application	application	NN
cord-010027-r0tl01kq	1859	26	.	.	.
cord-010027-r0tl01kq	1860	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1860	2	present	present	VBP
cord-010027-r0tl01kq	1860	3	a	a	DT
cord-010027-r0tl01kq	1860	4	'	'	``
cord-010027-r0tl01kq	1860	5	lean	lean	JJ
cord-010027-r0tl01kq	1860	6	'	'	''
cord-010027-r0tl01kq	1860	7	method	method	NN
cord-010027-r0tl01kq	1860	8	for	for	IN
cord-010027-r0tl01kq	1860	9	requesting	request	VBG
cord-010027-r0tl01kq	1860	10	molecular	molecular	JJ
cord-010027-r0tl01kq	1860	11	tests	test	NNS
cord-010027-r0tl01kq	1860	12	using	use	VBG
cord-010027-r0tl01kq	1860	13	a	a	DT
cord-010027-r0tl01kq	1860	14	smart	smart	JJ
cord-010027-r0tl01kq	1860	15	-	-	HYPH
cord-010027-r0tl01kq	1860	16	phone	phone	NN
cord-010027-r0tl01kq	1860	17	app	app	NN
cord-010027-r0tl01kq	1860	18	.	.	.
cord-010027-r0tl01kq	1861	1	This	this	DT
cord-010027-r0tl01kq	1861	2	application	application	NN
cord-010027-r0tl01kq	1861	3	can	can	MD
cord-010027-r0tl01kq	1861	4	be	be	VB
cord-010027-r0tl01kq	1861	5	used	use	VBN
cord-010027-r0tl01kq	1861	6	to	to	TO
cord-010027-r0tl01kq	1861	7	standardise	standardise	VB
cord-010027-r0tl01kq	1861	8	molecular	molecular	JJ
cord-010027-r0tl01kq	1861	9	test	test	NN
cord-010027-r0tl01kq	1861	10	request	request	NN
cord-010027-r0tl01kq	1861	11	forms	form	NNS
cord-010027-r0tl01kq	1861	12	within	within	IN
cord-010027-r0tl01kq	1861	13	the	the	DT
cord-010027-r0tl01kq	1861	14	NHS	NHS	NNP
cord-010027-r0tl01kq	1861	15	along	along	IN
cord-010027-r0tl01kq	1861	16	with	with	IN
cord-010027-r0tl01kq	1861	17	automatic	automatic	JJ
cord-010027-r0tl01kq	1861	18	generation	generation	NN
cord-010027-r0tl01kq	1861	19	of	of	IN
cord-010027-r0tl01kq	1861	20	a	a	DT
cord-010027-r0tl01kq	1861	21	national	national	JJ
cord-010027-r0tl01kq	1861	22	cancer	cancer	NN
cord-010027-r0tl01kq	1861	23	drugs	drug	NNS
cord-010027-r0tl01kq	1861	24	fund	fund	NN
cord-010027-r0tl01kq	1861	25	application	application	NN
cord-010027-r0tl01kq	1861	26	form	form	NN
cord-010027-r0tl01kq	1861	27	for	for	IN
cord-010027-r0tl01kq	1861	28	each	each	DT
cord-010027-r0tl01kq	1861	29	request	request	NN
cord-010027-r0tl01kq	1861	30	.	.	.
cord-010027-r0tl01kq	1862	1	Purpose	purpose	NN
cord-010027-r0tl01kq	1862	2	of	of	IN
cord-010027-r0tl01kq	1862	3	Study	Study	NNP
cord-010027-r0tl01kq	1862	4	:	:	:
cord-010027-r0tl01kq	1862	5	Automated	automate	VBN
cord-010027-r0tl01kq	1862	6	approaches	approach	NNS
cord-010027-r0tl01kq	1862	7	for	for	IN
cord-010027-r0tl01kq	1862	8	quantitative	quantitative	JJ
cord-010027-r0tl01kq	1862	9	digital	digital	JJ
cord-010027-r0tl01kq	1862	10	image	image	NN
cord-010027-r0tl01kq	1862	11	analysis	analysis	NN
cord-010027-r0tl01kq	1862	12	(	(	-LRB-
cord-010027-r0tl01kq	1862	13	DIA	DIA	NNP
cord-010027-r0tl01kq	1862	14	)	)	-RRB-
cord-010027-r0tl01kq	1862	15	of	of	IN
cord-010027-r0tl01kq	1862	16	tissues	tissue	NNS
cord-010027-r0tl01kq	1862	17	are	be	VBP
cord-010027-r0tl01kq	1862	18	becoming	become	VBG
cord-010027-r0tl01kq	1862	19	increasingly	increasingly	RB
cord-010027-r0tl01kq	1862	20	popular	popular	JJ
cord-010027-r0tl01kq	1862	21	in	in	IN
cord-010027-r0tl01kq	1862	22	pathology	pathology	NN
cord-010027-r0tl01kq	1862	23	due	due	IN
cord-010027-r0tl01kq	1862	24	to	to	IN
cord-010027-r0tl01kq	1862	25	advances	advance	NNS
cord-010027-r0tl01kq	1862	26	in	in	IN
cord-010027-r0tl01kq	1862	27	whole	whole	JJ
cord-010027-r0tl01kq	1862	28	slide	slide	NN
cord-010027-r0tl01kq	1862	29	scanning	scanning	NN
cord-010027-r0tl01kq	1862	30	hardware	hardware	NN
cord-010027-r0tl01kq	1862	31	and	and	CC
cord-010027-r0tl01kq	1862	32	digital	digital	JJ
cord-010027-r0tl01kq	1862	33	imaging	imaging	NN
cord-010027-r0tl01kq	1862	34	technology	technology	NN
cord-010027-r0tl01kq	1862	35	.	.	.
cord-010027-r0tl01kq	1863	1	It	-PRON-	PRP
cord-010027-r0tl01kq	1863	2	is	be	VBZ
cord-010027-r0tl01kq	1863	3	essential	essential	JJ
cord-010027-r0tl01kq	1863	4	that	that	IN
cord-010027-r0tl01kq	1863	5	DIA	DIA	NNP
cord-010027-r0tl01kq	1863	6	is	be	VBZ
cord-010027-r0tl01kq	1863	7	standardised	standardise	VBN
cord-010027-r0tl01kq	1863	8	to	to	TO
cord-010027-r0tl01kq	1863	9	ensure	ensure	VB
cord-010027-r0tl01kq	1863	10	accuracy	accuracy	NN
cord-010027-r0tl01kq	1863	11	and	and	CC
cord-010027-r0tl01kq	1863	12	reproducibility	reproducibility	NN
cord-010027-r0tl01kq	1863	13	of	of	IN
cord-010027-r0tl01kq	1863	14	results	result	NNS
cord-010027-r0tl01kq	1863	15	.	.	.
cord-010027-r0tl01kq	1864	1	Very	very	RB
cord-010027-r0tl01kq	1864	2	limited	limited	JJ
cord-010027-r0tl01kq	1864	3	published	publish	VBN
cord-010027-r0tl01kq	1864	4	data	data	NN
cord-010027-r0tl01kq	1864	5	exists	exist	VBZ
cord-010027-r0tl01kq	1864	6	on	on	IN
cord-010027-r0tl01kq	1864	7	the	the	DT
cord-010027-r0tl01kq	1864	8	effect	effect	NN
cord-010027-r0tl01kq	1864	9	of	of	IN
cord-010027-r0tl01kq	1864	10	scanner	scanner	NN
cord-010027-r0tl01kq	1864	11	hardware	hardware	NN
cord-010027-r0tl01kq	1864	12	variations	variation	NNS
cord-010027-r0tl01kq	1864	13	on	on	IN
cord-010027-r0tl01kq	1864	14	the	the	DT
cord-010027-r0tl01kq	1864	15	accuracy	accuracy	NN
cord-010027-r0tl01kq	1864	16	and	and	CC
cord-010027-r0tl01kq	1864	17	reproducibility	reproducibility	NN
cord-010027-r0tl01kq	1864	18	of	of	IN
cord-010027-r0tl01kq	1864	19	DIA	DIA	NNP
cord-010027-r0tl01kq	1864	20	results	result	NNS
cord-010027-r0tl01kq	1864	21	.	.	.
cord-010027-r0tl01kq	1865	1	The	the	DT
cord-010027-r0tl01kq	1865	2	aim	aim	NN
cord-010027-r0tl01kq	1865	3	of	of	IN
cord-010027-r0tl01kq	1865	4	this	this	DT
cord-010027-r0tl01kq	1865	5	study	study	NN
cord-010027-r0tl01kq	1865	6	was	be	VBD
cord-010027-r0tl01kq	1865	7	to	to	TO
cord-010027-r0tl01kq	1865	8	test	test	VB
cord-010027-r0tl01kq	1865	9	the	the	DT
cord-010027-r0tl01kq	1865	10	following	follow	VBG
cord-010027-r0tl01kq	1865	11	variables	variable	NNS
cord-010027-r0tl01kq	1865	12	:	:	:
cord-010027-r0tl01kq	1865	13	variation	variation	NN
cord-010027-r0tl01kq	1865	14	in	in	IN
cord-010027-r0tl01kq	1865	15	light	light	JJ
cord-010027-r0tl01kq	1865	16	source	source	NN
cord-010027-r0tl01kq	1865	17	intensity	intensity	NN
cord-010027-r0tl01kq	1865	18	during	during	IN
cord-010027-r0tl01kq	1865	19	the	the	DT
cord-010027-r0tl01kq	1865	20	day	day	NN
cord-010027-r0tl01kq	1865	21	;	;	:
cord-010027-r0tl01kq	1865	22	presnap	presnap	NNP
cord-010027-r0tl01kq	1865	23	calibration	calibration	NNP
cord-010027-r0tl01kq	1865	24	&	&	CC
cord-010027-r0tl01kq	1865	25	white	white	JJ
cord-010027-r0tl01kq	1865	26	balance	balance	NN
cord-010027-r0tl01kq	1865	27	of	of	IN
cord-010027-r0tl01kq	1865	28	scanned	scan	VBN
cord-010027-r0tl01kq	1865	29	images	image	NNS
cord-010027-r0tl01kq	1865	30	;	;	:
cord-010027-r0tl01kq	1865	31	variation	variation	NN
cord-010027-r0tl01kq	1865	32	in	in	IN
cord-010027-r0tl01kq	1865	33	DIA	DIA	NNP
cord-010027-r0tl01kq	1865	34	due	due	IN
cord-010027-r0tl01kq	1865	35	to	to	IN
cord-010027-r0tl01kq	1865	36	debris	debris	NN
cord-010027-r0tl01kq	1865	37	on	on	IN
cord-010027-r0tl01kq	1865	38	peripheral	peripheral	JJ
cord-010027-r0tl01kq	1865	39	parts	part	NNS
cord-010027-r0tl01kq	1865	40	of	of	IN
cord-010027-r0tl01kq	1865	41	the	the	DT
cord-010027-r0tl01kq	1865	42	section	section	NN
cord-010027-r0tl01kq	1865	43	or	or	CC
cord-010027-r0tl01kq	1865	44	coverslip	coverslip	NN
cord-010027-r0tl01kq	1865	45	edges	edge	NNS
cord-010027-r0tl01kq	1865	46	.	.	.
cord-010027-r0tl01kq	1866	1	Methods	method	NNS
cord-010027-r0tl01kq	1866	2	:	:	:
cord-010027-r0tl01kq	1867	1	Immunohistochemistry	immunohistochemistry	NN
cord-010027-r0tl01kq	1867	2	stained	stained	JJ
cord-010027-r0tl01kq	1867	3	sections	section	NNS
cord-010027-r0tl01kq	1867	4	from	from	IN
cord-010027-r0tl01kq	1867	5	3	3	CD
cord-010027-r0tl01kq	1867	6	patient	patient	NN
cord-010027-r0tl01kq	1867	7	samples	sample	NNS
cord-010027-r0tl01kq	1867	8	were	be	VBD
cord-010027-r0tl01kq	1867	9	scanned	scan	VBN
cord-010027-r0tl01kq	1867	10	on	on	IN
cord-010027-r0tl01kq	1867	11	the	the	DT
cord-010027-r0tl01kq	1867	12	same	same	JJ
cord-010027-r0tl01kq	1867	13	Aperio	Aperio	NNP
cord-010027-r0tl01kq	1867	14	CS	CS	NNP
cord-010027-r0tl01kq	1867	15	scanner	scanner	NN
cord-010027-r0tl01kq	1867	16	,	,	,
cord-010027-r0tl01kq	1867	17	hourly	hourly	JJ
cord-010027-r0tl01kq	1867	18	,	,	,
cord-010027-r0tl01kq	1867	19	for	for	IN
cord-010027-r0tl01kq	1867	20	2	2	CD
cord-010027-r0tl01kq	1867	21	consecutive	consecutive	JJ
cord-010027-r0tl01kq	1867	22	days	day	NNS
cord-010027-r0tl01kq	1867	23	to	to	TO
cord-010027-r0tl01kq	1867	24	generate	generate	VB
cord-010027-r0tl01kq	1867	25	15	15	CD
cord-010027-r0tl01kq	1867	26	scanned	scan	VBN
cord-010027-r0tl01kq	1867	27	images	image	NNS
cord-010027-r0tl01kq	1867	28	of	of	IN
cord-010027-r0tl01kq	1867	29	each	each	DT
cord-010027-r0tl01kq	1867	30	sample	sample	NN
cord-010027-r0tl01kq	1867	31	,	,	,
cord-010027-r0tl01kq	1867	32	representing	represent	VBG
cord-010027-r0tl01kq	1867	33	45	45	CD
cord-010027-r0tl01kq	1867	34	images	image	NNS
cord-010027-r0tl01kq	1867	35	in	in	IN
cord-010027-r0tl01kq	1867	36	total	total	NN
cord-010027-r0tl01kq	1867	37	.	.	.
cord-010027-r0tl01kq	1868	1	All	all	DT
cord-010027-r0tl01kq	1868	2	scanned	scan	VBN
cord-010027-r0tl01kq	1868	3	images	image	NNS
cord-010027-r0tl01kq	1868	4	were	be	VBD
cord-010027-r0tl01kq	1868	5	run	run	VBN
cord-010027-r0tl01kq	1868	6	through	through	IN
cord-010027-r0tl01kq	1868	7	Aperio	Aperio	NNP
cord-010027-r0tl01kq	1868	8	software	software	NN
cord-010027-r0tl01kq	1868	9	using	use	VBG
cord-010027-r0tl01kq	1868	10	a	a	DT
cord-010027-r0tl01kq	1868	11	macro	macro	NN
cord-010027-r0tl01kq	1868	12	to	to	TO
cord-010027-r0tl01kq	1868	13	quantify	quantify	VB
cord-010027-r0tl01kq	1868	14	positive	positive	JJ
cord-010027-r0tl01kq	1868	15	cell	cell	NN
cord-010027-r0tl01kq	1868	16	counts	count	NNS
cord-010027-r0tl01kq	1868	17	.	.	.
cord-010027-r0tl01kq	1869	1	For	for	IN
cord-010027-r0tl01kq	1869	2	a	a	DT
cord-010027-r0tl01kq	1869	3	subset	subset	NN
cord-010027-r0tl01kq	1869	4	of	of	IN
cord-010027-r0tl01kq	1869	5	images	image	NNS
cord-010027-r0tl01kq	1869	6	,	,	,
cord-010027-r0tl01kq	1869	7	a	a	DT
cord-010027-r0tl01kq	1869	8	region	region	NN
cord-010027-r0tl01kq	1869	9	of	of	IN
cord-010027-r0tl01kq	1869	10	interest	interest	NN
cord-010027-r0tl01kq	1869	11	was	be	VBD
cord-010027-r0tl01kq	1869	12	drawn	draw	VBN
cord-010027-r0tl01kq	1869	13	around	around	IN
cord-010027-r0tl01kq	1869	14	the	the	DT
cord-010027-r0tl01kq	1869	15	tissue	tissue	NN
cord-010027-r0tl01kq	1869	16	to	to	TO
cord-010027-r0tl01kq	1869	17	exclude	exclude	VB
cord-010027-r0tl01kq	1869	18	any	any	DT
cord-010027-r0tl01kq	1869	19	debris	debris	NN
cord-010027-r0tl01kq	1869	20	/	/	SYM
cord-010027-r0tl01kq	1869	21	coverslip	coverslip	NN
cord-010027-r0tl01kq	1869	22	edges	edge	NNS
cord-010027-r0tl01kq	1869	23	from	from	IN
cord-010027-r0tl01kq	1869	24	peripheral	peripheral	JJ
cord-010027-r0tl01kq	1869	25	parts	part	NNS
cord-010027-r0tl01kq	1869	26	of	of	IN
cord-010027-r0tl01kq	1869	27	the	the	DT
cord-010027-r0tl01kq	1869	28	slide	slide	NN
cord-010027-r0tl01kq	1869	29	in	in	IN
cord-010027-r0tl01kq	1869	30	the	the	DT
cord-010027-r0tl01kq	1869	31	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1869	32	DIA	dia	NN
cord-010027-r0tl01kq	1869	33	.	.	.
cord-010027-r0tl01kq	1870	1	Statistical	statistical	JJ
cord-010027-r0tl01kq	1870	2	analysis	analysis	NN
cord-010027-r0tl01kq	1870	3	was	be	VBD
cord-010027-r0tl01kq	1870	4	performed	perform	VBN
cord-010027-r0tl01kq	1870	5	to	to	TO
cord-010027-r0tl01kq	1870	6	calculate	calculate	VB
cord-010027-r0tl01kq	1870	7	the	the	DT
cord-010027-r0tl01kq	1870	8	coefficient	coefficient	NN
cord-010027-r0tl01kq	1870	9	of	of	IN
cord-010027-r0tl01kq	1870	10	variation	variation	NN
cord-010027-r0tl01kq	1870	11	between	between	IN
cord-010027-r0tl01kq	1870	12	DIA	DIA	NNP
cord-010027-r0tl01kq	1870	13	results	result	NNS
cord-010027-r0tl01kq	1870	14	from	from	IN
cord-010027-r0tl01kq	1870	15	scans	scan	NNS
cord-010027-r0tl01kq	1870	16	on	on	IN
cord-010027-r0tl01kq	1870	17	different	different	JJ
cord-010027-r0tl01kq	1870	18	days	day	NNS
cord-010027-r0tl01kq	1870	19	.	.	.
cord-010027-r0tl01kq	1871	1	Results	result	NNS
cord-010027-r0tl01kq	1871	2	:	:	:
cord-010027-r0tl01kq	1872	1	Variation	variation	NN
cord-010027-r0tl01kq	1872	2	in	in	IN
cord-010027-r0tl01kq	1872	3	light	light	JJ
cord-010027-r0tl01kq	1872	4	source	source	NN
cord-010027-r0tl01kq	1872	5	intensity	intensity	NN
cord-010027-r0tl01kq	1872	6	accounted	account	VBD
cord-010027-r0tl01kq	1872	7	for	for	IN
cord-010027-r0tl01kq	1872	8	1.2	1.2	CD
cord-010027-r0tl01kq	1872	9	%	%	NN
cord-010027-r0tl01kq	1872	10	to	to	IN
cord-010027-r0tl01kq	1872	11	2.1	2.1	CD
cord-010027-r0tl01kq	1872	12	%	%	NN
cord-010027-r0tl01kq	1872	13	variation	variation	NN
cord-010027-r0tl01kq	1872	14	in	in	IN
cord-010027-r0tl01kq	1872	15	cell	cell	NN
cord-010027-r0tl01kq	1872	16	counts	count	NNS
cord-010027-r0tl01kq	1872	17	between	between	IN
cord-010027-r0tl01kq	1872	18	repeat	repeat	NN
cord-010027-r0tl01kq	1872	19	scans	scan	NNS
cord-010027-r0tl01kq	1872	20	of	of	IN
cord-010027-r0tl01kq	1872	21	the	the	DT
cord-010027-r0tl01kq	1872	22	same	same	JJ
cord-010027-r0tl01kq	1872	23	slide	slide	NN
cord-010027-r0tl01kq	1872	24	.	.	.
cord-010027-r0tl01kq	1873	1	Exclusion	exclusion	NN
cord-010027-r0tl01kq	1873	2	of	of	IN
cord-010027-r0tl01kq	1873	3	debris	debris	NN
cord-010027-r0tl01kq	1873	4	/	/	SYM
cord-010027-r0tl01kq	1873	5	coverslip	coverslip	NN
cord-010027-r0tl01kq	1873	6	edges	edge	NNS
cord-010027-r0tl01kq	1873	7	accounted	account	VBD
cord-010027-r0tl01kq	1873	8	for	for	IN
cord-010027-r0tl01kq	1873	9	1	1	CD
cord-010027-r0tl01kq	1873	10	-	-	SYM
cord-010027-r0tl01kq	1873	11	2	2	CD
cord-010027-r0tl01kq	1873	12	%	%	NN
cord-010027-r0tl01kq	1873	13	variation	variation	NN
cord-010027-r0tl01kq	1873	14	in	in	IN
cord-010027-r0tl01kq	1873	15	cell	cell	NN
cord-010027-r0tl01kq	1873	16	counts	count	NNS
cord-010027-r0tl01kq	1873	17	between	between	IN
cord-010027-r0tl01kq	1873	18	repeat	repeat	NN
cord-010027-r0tl01kq	1873	19	scans	scan	NNS
cord-010027-r0tl01kq	1873	20	of	of	IN
cord-010027-r0tl01kq	1873	21	the	the	DT
cord-010027-r0tl01kq	1873	22	same	same	JJ
cord-010027-r0tl01kq	1873	23	slide	slide	NN
cord-010027-r0tl01kq	1873	24	.	.	.
cord-010027-r0tl01kq	1874	1	Subjective	subjective	JJ
cord-010027-r0tl01kq	1874	2	analysis	analysis	NN
cord-010027-r0tl01kq	1874	3	revealed	reveal	VBD
cord-010027-r0tl01kq	1874	4	no	no	DT
cord-010027-r0tl01kq	1874	5	significant	significant	JJ
cord-010027-r0tl01kq	1874	6	difference	difference	NN
cord-010027-r0tl01kq	1874	7	in	in	IN
cord-010027-r0tl01kq	1874	8	appearance	appearance	NN
cord-010027-r0tl01kq	1874	9	of	of	IN
cord-010027-r0tl01kq	1874	10	different	different	JJ
cord-010027-r0tl01kq	1874	11	scans	scan	NNS
cord-010027-r0tl01kq	1874	12	of	of	IN
cord-010027-r0tl01kq	1874	13	the	the	DT
cord-010027-r0tl01kq	1874	14	same	same	JJ
cord-010027-r0tl01kq	1874	15	slide	slide	NN
cord-010027-r0tl01kq	1874	16	.	.	.
cord-010027-r0tl01kq	1875	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1875	2	:	:	:
cord-010027-r0tl01kq	1876	1	Variation	variation	NN
cord-010027-r0tl01kq	1876	2	in	in	IN
cord-010027-r0tl01kq	1876	3	light	light	JJ
cord-010027-r0tl01kq	1876	4	source	source	NN
cord-010027-r0tl01kq	1876	5	intensity	intensity	NN
cord-010027-r0tl01kq	1876	6	,	,	,
cord-010027-r0tl01kq	1876	7	presnap	presnap	NN
cord-010027-r0tl01kq	1876	8	calibration	calibration	NN
cord-010027-r0tl01kq	1876	9	and	and	CC
cord-010027-r0tl01kq	1876	10	overall	overall	JJ
cord-010027-r0tl01kq	1876	11	white	white	JJ
cord-010027-r0tl01kq	1876	12	balance	balance	NN
cord-010027-r0tl01kq	1876	13	,	,	,
cord-010027-r0tl01kq	1876	14	plus	plus	CC
cord-010027-r0tl01kq	1876	15	debris	debris	NN
cord-010027-r0tl01kq	1876	16	in	in	IN
cord-010027-r0tl01kq	1876	17	peripheral	peripheral	JJ
cord-010027-r0tl01kq	1876	18	areas	area	NNS
cord-010027-r0tl01kq	1876	19	of	of	IN
cord-010027-r0tl01kq	1876	20	the	the	DT
cord-010027-r0tl01kq	1876	21	section	section	NN
cord-010027-r0tl01kq	1876	22	account	account	NN
cord-010027-r0tl01kq	1876	23	for	for	IN
cord-010027-r0tl01kq	1876	24	minimal	minimal	JJ
cord-010027-r0tl01kq	1876	25	variation	variation	NN
cord-010027-r0tl01kq	1876	26	in	in	IN
cord-010027-r0tl01kq	1876	27	resultant	resultant	JJ
cord-010027-r0tl01kq	1876	28	DIA	DIA	NNP
cord-010027-r0tl01kq	1876	29	results	result	NNS
cord-010027-r0tl01kq	1876	30	.	.	.
cord-010027-r0tl01kq	1877	1	Technical	technical	JJ
cord-010027-r0tl01kq	1877	2	advances	advance	NNS
cord-010027-r0tl01kq	1877	3	in	in	IN
cord-010027-r0tl01kq	1877	4	scanner	scanner	NN
cord-010027-r0tl01kq	1877	5	hardware	hardware	NN
cord-010027-r0tl01kq	1877	6	have	have	VBP
cord-010027-r0tl01kq	1877	7	reduced	reduce	VBN
cord-010027-r0tl01kq	1877	8	variability	variability	NN
cord-010027-r0tl01kq	1877	9	in	in	IN
cord-010027-r0tl01kq	1877	10	scanning	scanning	NN
cord-010027-r0tl01kq	1877	11	operations	operation	NNS
cord-010027-r0tl01kq	1877	12	.	.	.
cord-010027-r0tl01kq	1878	1	Further	further	JJ
cord-010027-r0tl01kq	1878	2	investigations	investigation	NNS
cord-010027-r0tl01kq	1878	3	are	be	VBP
cord-010027-r0tl01kq	1878	4	ongoing	ongoing	JJ
cord-010027-r0tl01kq	1878	5	.	.	.
cord-010027-r0tl01kq	1879	1	The	the	DT
cord-010027-r0tl01kq	1879	2	Complexity	complexity	NN
cord-010027-r0tl01kq	1879	3	of	of	IN
cord-010027-r0tl01kq	1879	4	Ovarian	Ovarian	NNP
cord-010027-r0tl01kq	1879	5	Cancer	Cancer	NNP
cord-010027-r0tl01kq	1879	6	Resistance	Resistance	NNP
cord-010027-r0tl01kq	1879	7	Mechanisms	Mechanisms	NNPS
cord-010027-r0tl01kq	1879	8	:	:	:
cord-010027-r0tl01kq	1879	9	A	a	DT
cord-010027-r0tl01kq	1879	10	Novel	Novel	NNP
cord-010027-r0tl01kq	1879	11	,	,	,
cord-010027-r0tl01kq	1879	12	Clinically	clinically	RB
cord-010027-r0tl01kq	1879	13	Relevant	relevant	JJ
cord-010027-r0tl01kq	1879	14	,	,	,
cord-010027-r0tl01kq	1879	15	in	in	IN
cord-010027-r0tl01kq	1879	16	-	-	HYPH
cord-010027-r0tl01kq	1879	17	vitro	vitro	FW
cord-010027-r0tl01kq	1879	18	Investigation	investigation	NN
cord-010027-r0tl01kq	1879	19	P	P	NNP
cord-010027-r0tl01kq	1879	20	S	S	NNP
cord-010027-r0tl01kq	1879	21	Busschots	Busschots	NNP
cord-010027-r0tl01kq	1879	22	1	1	CD
cord-010027-r0tl01kq	1879	23	G	G	NNP
cord-010027-r0tl01kq	1879	24	Blackshields	Blackshields	NNP
cord-010027-r0tl01kq	1879	25	1	1	CD
cord-010027-r0tl01kq	1879	26	;	;	:
cord-010027-r0tl01kq	1879	27	BT	BT	NNP
cord-010027-r0tl01kq	1879	28	Hennessy	Hennessy	NNP
cord-010027-r0tl01kq	1879	29	3	3	CD
cord-010027-r0tl01kq	1879	30	Novel	Novel	NNP
cord-010027-r0tl01kq	1879	31	carboplatin	carboplatin	NNS
cord-010027-r0tl01kq	1879	32	and	and	CC
cord-010027-r0tl01kq	1879	33	taxol	taxol	NN
cord-010027-r0tl01kq	1879	34	resistant	resistant	JJ
cord-010027-r0tl01kq	1879	35	cell	cell	NN
cord-010027-r0tl01kq	1879	36	lines	line	NNS
cord-010027-r0tl01kq	1879	37	were	be	VBD
cord-010027-r0tl01kq	1879	38	developed	develop	VBN
cord-010027-r0tl01kq	1879	39	from	from	IN
cord-010027-r0tl01kq	1879	40	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1879	41	OC	OC	NNP
cord-010027-r0tl01kq	1879	42	cells	cell	NNS
cord-010027-r0tl01kq	1879	43	in	in	IN
cord-010027-r0tl01kq	1879	44	a	a	DT
cord-010027-r0tl01kq	1879	45	clinically	clinically	RB
cord-010027-r0tl01kq	1879	46	relevant	relevant	JJ
cord-010027-r0tl01kq	1879	47	selection	selection	NN
cord-010027-r0tl01kq	1879	48	strategy	strategy	NN
cord-010027-r0tl01kq	1879	49	to	to	TO
cord-010027-r0tl01kq	1879	50	better	better	RB
cord-010027-r0tl01kq	1879	51	understand	understand	VB
cord-010027-r0tl01kq	1879	52	resistant	resistant	JJ
cord-010027-r0tl01kq	1879	53	mechanisms	mechanism	NNS
cord-010027-r0tl01kq	1879	54	in	in	IN
cord-010027-r0tl01kq	1879	55	OC	OC	NNP
cord-010027-r0tl01kq	1879	56	.	.	.
cord-010027-r0tl01kq	1880	1	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1880	2	-	-	HYPH
cord-010027-r0tl01kq	1880	3	7C	7C	NNP
cord-010027-r0tl01kq	1880	4	models	model	NNS
cord-010027-r0tl01kq	1880	5	carboplatin	carboplatin	VBP
cord-010027-r0tl01kq	1880	6	resistance	resistance	NN
cord-010027-r0tl01kq	1880	7	and	and	CC
cord-010027-r0tl01kq	1880	8	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1880	9	-	-	HYPH
cord-010027-r0tl01kq	1880	10	7	7	CD
cord-010027-r0tl01kq	1880	11	T	T	NNP
cord-010027-r0tl01kq	1880	12	models	model	NNS
cord-010027-r0tl01kq	1880	13	taxol	taxol	NNP
cord-010027-r0tl01kq	1880	14	resistance	resistance	NN
cord-010027-r0tl01kq	1880	15	.	.	.
cord-010027-r0tl01kq	1881	1	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1881	2	-	-	HYPH
cord-010027-r0tl01kq	1881	3	6CALT	6calt	CD
cord-010027-r0tl01kq	1881	4	and	and	CC
cord-010027-r0tl01kq	1881	5	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1881	6	-	-	HYPH
cord-010027-r0tl01kq	1881	7	6TALT	6talt	CD
cord-010027-r0tl01kq	1881	8	were	be	VBD
cord-010027-r0tl01kq	1881	9	exposed	expose	VBN
cord-010027-r0tl01kq	1881	10	to	to	IN
cord-010027-r0tl01kq	1881	11	alternating	alternate	VBG
cord-010027-r0tl01kq	1881	12	treatments	treatment	NNS
cord-010027-r0tl01kq	1881	13	of	of	IN
cord-010027-r0tl01kq	1881	14	both	both	DT
cord-010027-r0tl01kq	1881	15	agents	agent	NNS
cord-010027-r0tl01kq	1881	16	during	during	IN
cord-010027-r0tl01kq	1881	17	development	development	NN
cord-010027-r0tl01kq	1881	18	.	.	.
cord-010027-r0tl01kq	1882	1	Affymetrix	Affymetrix	NNP
cord-010027-r0tl01kq	1882	2	arrays	array	NNS
cord-010027-r0tl01kq	1882	3	were	be	VBD
cord-010027-r0tl01kq	1882	4	used	use	VBN
cord-010027-r0tl01kq	1882	5	to	to	TO
cord-010027-r0tl01kq	1882	6	characterise	characterise	VB
cord-010027-r0tl01kq	1882	7	gene	gene	NN
cord-010027-r0tl01kq	1882	8	/	/	SYM
cord-010027-r0tl01kq	1882	9	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1882	10	signatures	signature	NNS
cord-010027-r0tl01kq	1882	11	linked	link	VBN
cord-010027-r0tl01kq	1882	12	with	with	IN
cord-010027-r0tl01kq	1882	13	the	the	DT
cord-010027-r0tl01kq	1882	14	development	development	NN
cord-010027-r0tl01kq	1882	15	of	of	IN
cord-010027-r0tl01kq	1882	16	chemoresistance	chemoresistance	NN
cord-010027-r0tl01kq	1882	17	in	in	IN
cord-010027-r0tl01kq	1882	18	OC	OC	NNP
cord-010027-r0tl01kq	1882	19	cell	cell	NN
cord-010027-r0tl01kq	1882	20	lines	line	NNS
cord-010027-r0tl01kq	1882	21	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1882	22	-	-	HYPH
cord-010027-r0tl01kq	1882	23	7C	7C	NNP
cord-010027-r0tl01kq	1882	24	and	and	CC
cord-010027-r0tl01kq	1882	25	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1882	26	-	-	HYPH
cord-010027-r0tl01kq	1882	27	7T.	7t.	CD
cord-010027-r0tl01kq	1882	28	Bioconductor	Bioconductor	NNP
cord-010027-r0tl01kq	1882	29	software	software	NN
cord-010027-r0tl01kq	1882	30	,	,	,
cord-010027-r0tl01kq	1882	31	DAVID	DAVID	NNP
cord-010027-r0tl01kq	1882	32	v6.7	v6.7	NNP
cord-010027-r0tl01kq	1882	33	and	and	CC
cord-010027-r0tl01kq	1882	34	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1882	35	-	-	HYPH
cord-010027-r0tl01kq	1882	36	target	target	NN
cord-010027-r0tl01kq	1882	37	interactions	interaction	NNS
cord-010027-r0tl01kq	1882	38	(	(	-LRB-
cord-010027-r0tl01kq	1882	39	MTIs	mtis	NN
cord-010027-r0tl01kq	1882	40	)	)	-RRB-
cord-010027-r0tl01kq	1882	41	analysis	analysis	NN
cord-010027-r0tl01kq	1882	42	was	be	VBD
cord-010027-r0tl01kq	1882	43	carried	carry	VBN
cord-010027-r0tl01kq	1882	44	out	out	RP
cord-010027-r0tl01kq	1882	45	to	to	TO
cord-010027-r0tl01kq	1882	46	identify	identify	VB
cord-010027-r0tl01kq	1882	47	de	de	NNP
cord-010027-r0tl01kq	1882	48	-	-	JJ
cord-010027-r0tl01kq	1882	49	regulated	regulate	VBN
cord-010027-r0tl01kq	1882	50	genes/	genes/	NN
cord-010027-r0tl01kq	1883	1	miRNAs	miRNAs	NNP
cord-010027-r0tl01kq	1883	2	,	,	,
cord-010027-r0tl01kq	1883	3	gene	gene	NN
cord-010027-r0tl01kq	1883	4	pathways	pathway	NNS
cord-010027-r0tl01kq	1883	5	and	and	CC
cord-010027-r0tl01kq	1883	6	gene	gene	NN
cord-010027-r0tl01kq	1883	7	/	/	SYM
cord-010027-r0tl01kq	1883	8	miRNA	miRNA	NNP
cord-010027-r0tl01kq	1883	9	interactions	interaction	NNS
cord-010027-r0tl01kq	1883	10	involved	involve	VBN
cord-010027-r0tl01kq	1883	11	in	in	IN
cord-010027-r0tl01kq	1883	12	resistance	resistance	NN
cord-010027-r0tl01kq	1883	13	.	.	.
cord-010027-r0tl01kq	1884	1	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1884	2	sublines	sublines	NNP
cord-010027-r0tl01kq	1884	3	developed	develop	VBD
cord-010027-r0tl01kq	1884	4	using	use	VBG
cord-010027-r0tl01kq	1884	5	taxol	taxol	NN
cord-010027-r0tl01kq	1884	6	were	be	VBD
cord-010027-r0tl01kq	1884	7	significantly	significantly	RB
cord-010027-r0tl01kq	1884	8	resistant	resistant	JJ
cord-010027-r0tl01kq	1884	9	to	to	IN
cord-010027-r0tl01kq	1884	10	taxol	taxol	NN
cord-010027-r0tl01kq	1884	11	,	,	,
cord-010027-r0tl01kq	1884	12	vinblastine	vinblastine	NN
cord-010027-r0tl01kq	1884	13	and	and	CC
cord-010027-r0tl01kq	1884	14	olaparib	olaparib	NN
cord-010027-r0tl01kq	1884	15	(	(	-LRB-
cord-010027-r0tl01kq	1884	16	P	p	NN
cord-010027-r0tl01kq	1884	17	-	-	HYPH
cord-010027-r0tl01kq	1884	18	gp	gp	NN
cord-010027-r0tl01kq	1884	19	substrates	substrate	NNS
cord-010027-r0tl01kq	1884	20	)	)	-RRB-
cord-010027-r0tl01kq	1884	21	,	,	,
cord-010027-r0tl01kq	1884	22	and	and	CC
cord-010027-r0tl01kq	1884	23	reversible	reversible	JJ
cord-010027-r0tl01kq	1884	24	with	with	IN
cord-010027-r0tl01kq	1884	25	elacridar	elacridar	NNP
cord-010027-r0tl01kq	1884	26	(	(	-LRB-
cord-010027-r0tl01kq	1884	27	P	p	NN
cord-010027-r0tl01kq	1884	28	-	-	HYPH
cord-010027-r0tl01kq	1884	29	gp	gp	NN
cord-010027-r0tl01kq	1884	30	inhibitor	inhibitor	NN
cord-010027-r0tl01kq	1884	31	)	)	-RRB-
cord-010027-r0tl01kq	1884	32	treatment	treatment	NN
cord-010027-r0tl01kq	1884	33	.	.	.
cord-010027-r0tl01kq	1885	1	Significant	significant	JJ
cord-010027-r0tl01kq	1885	2	up	up	JJ
cord-010027-r0tl01kq	1885	3	-	-	HYPH
cord-010027-r0tl01kq	1885	4	regulation	regulation	NN
cord-010027-r0tl01kq	1885	5	ABCB1	ABCB1	NNP
cord-010027-r0tl01kq	1885	6	was	be	VBD
cord-010027-r0tl01kq	1885	7	seen	see	VBN
cord-010027-r0tl01kq	1885	8	in	in	IN
cord-010027-r0tl01kq	1885	9	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1885	10	-	-	HYPH
cord-010027-r0tl01kq	1885	11	7	7	CD
cord-010027-r0tl01kq	1885	12	T	t	NN
cord-010027-r0tl01kq	1885	13	which	which	WDT
cord-010027-r0tl01kq	1885	14	was	be	VBD
cord-010027-r0tl01kq	1885	15	reflected	reflect	VBN
cord-010027-r0tl01kq	1885	16	at	at	IN
cord-010027-r0tl01kq	1885	17	the	the	DT
cord-010027-r0tl01kq	1885	18	protein	protein	NN
cord-010027-r0tl01kq	1885	19	level	level	NN
cord-010027-r0tl01kq	1885	20	.	.	.
cord-010027-r0tl01kq	1886	1	SRPX2	SRPX2	NNP
cord-010027-r0tl01kq	1886	2	was	be	VBD
cord-010027-r0tl01kq	1886	3	highly	highly	RB
cord-010027-r0tl01kq	1886	4	up	up	RB
cord-010027-r0tl01kq	1886	5	-	-	HYPH
cord-010027-r0tl01kq	1886	6	regulated	regulate	VBN
cord-010027-r0tl01kq	1886	7	in	in	IN
cord-010027-r0tl01kq	1886	8	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1886	9	-	-	HYPH
cord-010027-r0tl01kq	1886	10	7T.	7t.	CD
cord-010027-r0tl01kq	1886	11	GLI3	GLI3	NNP
cord-010027-r0tl01kq	1887	1	and	and	CC
cord-010027-r0tl01kq	1887	2	CCL20	CCL20	NNP
cord-010027-r0tl01kq	1887	3	were	be	VBD
cord-010027-r0tl01kq	1887	4	up	up	RB
cord-010027-r0tl01kq	1887	5	/	/	SYM
cord-010027-r0tl01kq	1887	6	down	down	RB
cord-010027-r0tl01kq	1887	7	-	-	HYPH
cord-010027-r0tl01kq	1887	8	regulated	regulate	VBN
cord-010027-r0tl01kq	1887	9	respectively	respectively	RB
cord-010027-r0tl01kq	1887	10	in	in	IN
cord-010027-r0tl01kq	1887	11	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1887	12	-	-	HYPH
cord-010027-r0tl01kq	1887	13	7C.	7c.	CD
cord-010027-r0tl01kq	1887	14	GLI3	GLI3	NNP
cord-010027-r0tl01kq	1888	1	had	have	VBD
cord-010027-r0tl01kq	1888	2	a	a	DT
cord-010027-r0tl01kq	1888	3	validated	validate	VBN
cord-010027-r0tl01kq	1888	4	interaction	interaction	NN
cord-010027-r0tl01kq	1888	5	with	with	IN
cord-010027-r0tl01kq	1888	6	miR-205	mir-205	JJ
cord-010027-r0tl01kq	1888	7	down	down	RB
cord-010027-r0tl01kq	1888	8	-	-	HYPH
cord-010027-r0tl01kq	1888	9	regulated	regulate	VBN
cord-010027-r0tl01kq	1888	10	in	in	IN
cord-010027-r0tl01kq	1889	1	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1889	2	-	-	HYPH
cord-010027-r0tl01kq	1889	3	7C.	7c.	CD
cord-010027-r0tl01kq	1889	4	LIN28B	lin28b	NN
cord-010027-r0tl01kq	1889	5	was	be	VBD
cord-010027-r0tl01kq	1889	6	highly	highly	RB
cord-010027-r0tl01kq	1889	7	deregulated	deregulate	VBN
cord-010027-r0tl01kq	1889	8	in	in	IN
cord-010027-r0tl01kq	1889	9	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1889	10	-	-	HYPH
cord-010027-r0tl01kq	1889	11	7C	7C	NNP
cord-010027-r0tl01kq	1889	12	and	and	CC
cord-010027-r0tl01kq	1889	13	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1889	14	-	-	HYPH
cord-010027-r0tl01kq	1889	15	7	7	CD
cord-010027-r0tl01kq	1889	16	T	t	NN
cord-010027-r0tl01kq	1889	17	and	and	CC
cord-010027-r0tl01kq	1889	18	had	have	VBD
cord-010027-r0tl01kq	1889	19	a	a	DT
cord-010027-r0tl01kq	1889	20	validated	validate	VBN
cord-010027-r0tl01kq	1889	21	interaction	interaction	NN
cord-010027-r0tl01kq	1889	22	with	with	IN
cord-010027-r0tl01kq	1889	23	let-7i	let-7i	NNP
cord-010027-r0tl01kq	1889	24	,	,	,
cord-010027-r0tl01kq	1889	25	down	down	RB
cord-010027-r0tl01kq	1889	26	-	-	HYPH
cord-010027-r0tl01kq	1889	27	regulated	regulate	VBN
cord-010027-r0tl01kq	1889	28	in	in	IN
cord-010027-r0tl01kq	1889	29	UPN251	UPN251	NNP
cord-010027-r0tl01kq	1889	30	-	-	HYPH
cord-010027-r0tl01kq	1889	31	7C.	7c.	CD
cord-010027-r0tl01kq	1889	32	P	p	NN
cord-010027-r0tl01kq	1889	33	-	-	HYPH
cord-010027-r0tl01kq	1889	34	gp	gp	NN
cord-010027-r0tl01kq	1889	35	over	over	IN
cord-010027-r0tl01kq	1889	36	-	-	HYPH
cord-010027-r0tl01kq	1889	37	expression	expression	NN
cord-010027-r0tl01kq	1889	38	is	be	VBZ
cord-010027-r0tl01kq	1889	39	a	a	DT
cord-010027-r0tl01kq	1889	40	dominant	dominant	JJ
cord-010027-r0tl01kq	1889	41	mechanism	mechanism	NN
cord-010027-r0tl01kq	1889	42	for	for	IN
cord-010027-r0tl01kq	1889	43	taxol	taxol	NN
cord-010027-r0tl01kq	1889	44	resistance	resistance	NN
cord-010027-r0tl01kq	1889	45	in	in	IN
cord-010027-r0tl01kq	1889	46	our	-PRON-	PRP$
cord-010027-r0tl01kq	1889	47	cell	cell	NN
cord-010027-r0tl01kq	1889	48	lines	line	NNS
cord-010027-r0tl01kq	1889	49	.	.	.
cord-010027-r0tl01kq	1890	1	Mechanisms	mechanism	NNS
cord-010027-r0tl01kq	1890	2	for	for	IN
cord-010027-r0tl01kq	1890	3	carboplatin	carboplatin	NN
cord-010027-r0tl01kq	1890	4	resistance	resistance	NN
cord-010027-r0tl01kq	1890	5	are	be	VBP
cord-010027-r0tl01kq	1890	6	more	more	RBR
cord-010027-r0tl01kq	1890	7	complicated	complicated	JJ
cord-010027-r0tl01kq	1890	8	.	.	.
cord-010027-r0tl01kq	1891	1	The	the	DT
cord-010027-r0tl01kq	1891	2	top	top	JJ
cord-010027-r0tl01kq	1891	3	deregulated	deregulate	VBN
cord-010027-r0tl01kq	1891	4	genes	gene	NNS
cord-010027-r0tl01kq	1891	5	are	be	VBP
cord-010027-r0tl01kq	1891	6	involved	involve	VBN
cord-010027-r0tl01kq	1891	7	in	in	IN
cord-010027-r0tl01kq	1891	8	numerous	numerous	JJ
cord-010027-r0tl01kq	1891	9	pathways	pathway	NNS
cord-010027-r0tl01kq	1891	10	including	include	VBG
cord-010027-r0tl01kq	1891	11	apoptosis	apoptosis	NN
cord-010027-r0tl01kq	1891	12	,	,	,
cord-010027-r0tl01kq	1891	13	cellular	cellular	JJ
cord-010027-r0tl01kq	1891	14	transformation	transformation	NN
cord-010027-r0tl01kq	1891	15	,	,	,
cord-010027-r0tl01kq	1891	16	signal	signal	NN
cord-010027-r0tl01kq	1891	17	transduction	transduction	NN
cord-010027-r0tl01kq	1891	18	,	,	,
cord-010027-r0tl01kq	1891	19	and	and	CC
cord-010027-r0tl01kq	1891	20	cell	cell	NN
cord-010027-r0tl01kq	1891	21	migration	migration	NN
cord-010027-r0tl01kq	1891	22	Cervical	Cervical	NNP
cord-010027-r0tl01kq	1891	23	Glandular	glandular	JJ
cord-010027-r0tl01kq	1891	24	Neoplasia	Neoplasia	NNP
cord-010027-r0tl01kq	1891	25	:	:	:
cord-010027-r0tl01kq	1892	1	The	the	DT
cord-010027-r0tl01kq	1892	2	Influence	influence	NN
cord-010027-r0tl01kq	1892	3	of	of	IN
cord-010027-r0tl01kq	1892	4	Excision	Excision	NNP
cord-010027-r0tl01kq	1892	5	Procedure	Procedure	NNP
cord-010027-r0tl01kq	1892	6	on	on	IN
cord-010027-r0tl01kq	1892	7	Margin	Margin	NNP
cord-010027-r0tl01kq	1892	8	Status	status	NN
cord-010027-r0tl01kq	1893	1	Although	although	IN
cord-010027-r0tl01kq	1893	2	cold	cold	JJ
cord-010027-r0tl01kq	1893	3	knife	knife	NN
cord-010027-r0tl01kq	1893	4	cones	cone	NNS
cord-010027-r0tl01kq	1893	5	(	(	-LRB-
cord-010027-r0tl01kq	1893	6	CKC	CKC	NNP
cord-010027-r0tl01kq	1893	7	)	)	-RRB-
cord-010027-r0tl01kq	1893	8	have	have	VBP
cord-010027-r0tl01kq	1893	9	been	be	VBN
cord-010027-r0tl01kq	1893	10	traditionally	traditionally	RB
cord-010027-r0tl01kq	1893	11	advocated	advocate	VBN
cord-010027-r0tl01kq	1893	12	for	for	IN
cord-010027-r0tl01kq	1893	13	treatment	treatment	NN
cord-010027-r0tl01kq	1893	14	of	of	IN
cord-010027-r0tl01kq	1893	15	adenocarcinoma	adenocarcinoma	NN
cord-010027-r0tl01kq	1893	16	in	in	IN
cord-010027-r0tl01kq	1893	17	situ	situ	FW
cord-010027-r0tl01kq	1893	18	(	(	-LRB-
cord-010027-r0tl01kq	1893	19	AIS	AIS	NNP
cord-010027-r0tl01kq	1893	20	)	)	-RRB-
cord-010027-r0tl01kq	1893	21	,	,	,
cord-010027-r0tl01kq	1893	22	large	large	JJ
cord-010027-r0tl01kq	1893	23	loop	loop	NN
cord-010027-r0tl01kq	1893	24	excisions	excision	NNS
cord-010027-r0tl01kq	1893	25	of	of	IN
cord-010027-r0tl01kq	1893	26	the	the	DT
cord-010027-r0tl01kq	1893	27	transformation	transformation	NN
cord-010027-r0tl01kq	1893	28	zone	zone	NN
cord-010027-r0tl01kq	1893	29	(	(	-LRB-
cord-010027-r0tl01kq	1893	30	LLETZ	LLETZ	NNP
cord-010027-r0tl01kq	1893	31	)	)	-RRB-
cord-010027-r0tl01kq	1893	32	are	be	VBP
cord-010027-r0tl01kq	1893	33	increasingly	increasingly	RB
cord-010027-r0tl01kq	1893	34	used	use	VBN
cord-010027-r0tl01kq	1893	35	.	.	.
cord-010027-r0tl01kq	1894	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1894	2	analysed	analyse	VBD
cord-010027-r0tl01kq	1894	3	excisions	excision	NNS
cord-010027-r0tl01kq	1894	4	from	from	IN
cord-010027-r0tl01kq	1894	5	111	111	CD
cord-010027-r0tl01kq	1894	6	patients	patient	NNS
cord-010027-r0tl01kq	1894	7	where	where	WRB
cord-010027-r0tl01kq	1894	8	AIS	AIS	NNP
cord-010027-r0tl01kq	1894	9	was	be	VBD
cord-010027-r0tl01kq	1894	10	confirmed	confirm	VBN
cord-010027-r0tl01kq	1894	11	prior	prior	RB
cord-010027-r0tl01kq	1894	12	to	to	IN
cord-010027-r0tl01kq	1894	13	procedure	procedure	NN
cord-010027-r0tl01kq	1894	14	over	over	IN
cord-010027-r0tl01kq	1894	15	5	5	CD
cord-010027-r0tl01kq	1894	16	years	year	NNS
cord-010027-r0tl01kq	1894	17	to	to	TO
cord-010027-r0tl01kq	1894	18	assess	assess	VB
cord-010027-r0tl01kq	1894	19	the	the	DT
cord-010027-r0tl01kq	1894	20	influence	influence	NN
cord-010027-r0tl01kq	1894	21	of	of	IN
cord-010027-r0tl01kq	1894	22	excision	excision	NN
cord-010027-r0tl01kq	1894	23	procedure	procedure	NN
cord-010027-r0tl01kq	1894	24	on	on	IN
cord-010027-r0tl01kq	1894	25	final	final	JJ
cord-010027-r0tl01kq	1894	26	margin	margin	NN
cord-010027-r0tl01kq	1894	27	status	status	NN
cord-010027-r0tl01kq	1894	28	.	.	.
cord-010027-r0tl01kq	1895	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1895	2	tabulated	tabulate	VBD
cord-010027-r0tl01kq	1895	3	whether	whether	IN
cord-010027-r0tl01kq	1895	4	margins	margin	NNS
cord-010027-r0tl01kq	1895	5	were	be	VBD
cord-010027-r0tl01kq	1895	6	involved	involve	VBN
cord-010027-r0tl01kq	1895	7	,	,	,
cord-010027-r0tl01kq	1895	8	close	close	JJ
cord-010027-r0tl01kq	1895	9	(	(	-LRB-
cord-010027-r0tl01kq	1895	10	lesional	lesional	JJ
cord-010027-r0tl01kq	1895	11	tissue	tissue	NN
cord-010027-r0tl01kq	1895	12	less	less	JJR
cord-010027-r0tl01kq	1895	13	than	than	IN
cord-010027-r0tl01kq	1895	14	5	5	CD
cord-010027-r0tl01kq	1895	15	mm	mm	NN
cord-010027-r0tl01kq	1895	16	from	from	IN
cord-010027-r0tl01kq	1895	17	margin	margin	NN
cord-010027-r0tl01kq	1895	18	)	)	-RRB-
cord-010027-r0tl01kq	1895	19	or	or	CC
cord-010027-r0tl01kq	1895	20	excised	excise	VBN
cord-010027-r0tl01kq	1895	21	.	.	.
cord-010027-r0tl01kq	1896	1	Results	result	NNS
cord-010027-r0tl01kq	1896	2	:	:	:
cord-010027-r0tl01kq	1897	1	LLETZs	LLETZs	NNP
cord-010027-r0tl01kq	1897	2	were	be	VBD
cord-010027-r0tl01kq	1897	3	performed	perform	VBN
cord-010027-r0tl01kq	1897	4	in	in	IN
cord-010027-r0tl01kq	1897	5	70	70	CD
cord-010027-r0tl01kq	1897	6	%	%	NN
cord-010027-r0tl01kq	1897	7	(	(	-LRB-
cord-010027-r0tl01kq	1897	8	78	78	CD
cord-010027-r0tl01kq	1897	9	of	of	IN
cord-010027-r0tl01kq	1897	10	111	111	CD
cord-010027-r0tl01kq	1897	11	patients	patient	NNS
cord-010027-r0tl01kq	1897	12	)	)	-RRB-
cord-010027-r0tl01kq	1897	13	,	,	,
cord-010027-r0tl01kq	1897	14	CKC	CKC	NNP
cord-010027-r0tl01kq	1897	15	excision	excision	NN
cord-010027-r0tl01kq	1897	16	in	in	IN
cord-010027-r0tl01kq	1897	17	30	30	CD
cord-010027-r0tl01kq	1897	18	%	%	NN
cord-010027-r0tl01kq	1897	19	(	(	-LRB-
cord-010027-r0tl01kq	1897	20	33	33	CD
cord-010027-r0tl01kq	1897	21	of	of	IN
cord-010027-r0tl01kq	1897	22	111	111	CD
cord-010027-r0tl01kq	1897	23	)	)	-RRB-
cord-010027-r0tl01kq	1897	24	.	.	.
cord-010027-r0tl01kq	1898	1	Women	woman	NNS
cord-010027-r0tl01kq	1898	2	who	who	WP
cord-010027-r0tl01kq	1898	3	had	have	VBD
cord-010027-r0tl01kq	1898	4	LLETZs	lletz	NNS
cord-010027-r0tl01kq	1898	5	were	be	VBD
cord-010027-r0tl01kq	1898	6	younger	young	JJR
cord-010027-r0tl01kq	1898	7	than	than	IN
cord-010027-r0tl01kq	1898	8	those	those	DT
cord-010027-r0tl01kq	1898	9	having	have	VBG
cord-010027-r0tl01kq	1898	10	CKC	CKC	NNP
cord-010027-r0tl01kq	1898	11	excision	excision	NN
cord-010027-r0tl01kq	1898	12	(	(	-LRB-
cord-010027-r0tl01kq	1898	13	32.8	32.8	CD
cord-010027-r0tl01kq	1898	14	years	year	NNS
cord-010027-r0tl01kq	1898	15	versus	versus	IN
cord-010027-r0tl01kq	1898	16	35.4	35.4	CD
cord-010027-r0tl01kq	1898	17	years	year	NNS
cord-010027-r0tl01kq	1898	18	)	)	-RRB-
cord-010027-r0tl01kq	1898	19	.	.	.
cord-010027-r0tl01kq	1899	1	Positive	positive	JJ
cord-010027-r0tl01kq	1899	2	margins	margin	NNS
cord-010027-r0tl01kq	1899	3	were	be	VBD
cord-010027-r0tl01kq	1899	4	present	present	JJ
cord-010027-r0tl01kq	1899	5	in	in	IN
cord-010027-r0tl01kq	1899	6	21	21	CD
cord-010027-r0tl01kq	1899	7	%	%	NN
cord-010027-r0tl01kq	1899	8	(	(	-LRB-
cord-010027-r0tl01kq	1899	9	16	16	CD
cord-010027-r0tl01kq	1899	10	of	of	IN
cord-010027-r0tl01kq	1899	11	78	78	CD
cord-010027-r0tl01kq	1899	12	)	)	-RRB-
cord-010027-r0tl01kq	1899	13	and	and	CC
cord-010027-r0tl01kq	1899	14	close	close	JJ
cord-010027-r0tl01kq	1899	15	margins	margin	NNS
cord-010027-r0tl01kq	1899	16	in	in	IN
cord-010027-r0tl01kq	1899	17	27	27	CD
cord-010027-r0tl01kq	1899	18	%	%	NN
cord-010027-r0tl01kq	1899	19	(	(	-LRB-
cord-010027-r0tl01kq	1899	20	21	21	CD
cord-010027-r0tl01kq	1899	21	of	of	IN
cord-010027-r0tl01kq	1899	22	78	78	CD
cord-010027-r0tl01kq	1899	23	)	)	-RRB-
cord-010027-r0tl01kq	1899	24	LLETZ	LLETZ	NNP
cord-010027-r0tl01kq	1899	25	cases	case	NNS
cord-010027-r0tl01kq	1899	26	.	.	.
cord-010027-r0tl01kq	1900	1	For	for	IN
cord-010027-r0tl01kq	1900	2	CKC	CKC	NNP
cord-010027-r0tl01kq	1900	3	,	,	,
cord-010027-r0tl01kq	1900	4	margins	margin	NNS
cord-010027-r0tl01kq	1900	5	were	be	VBD
cord-010027-r0tl01kq	1900	6	positive	positive	JJ
cord-010027-r0tl01kq	1900	7	in	in	IN
cord-010027-r0tl01kq	1900	8	9	9	CD
cord-010027-r0tl01kq	1900	9	%	%	NN
cord-010027-r0tl01kq	1900	10	of	of	IN
cord-010027-r0tl01kq	1900	11	cases	case	NNS
cord-010027-r0tl01kq	1900	12	(	(	-LRB-
cord-010027-r0tl01kq	1900	13	3	3	CD
cord-010027-r0tl01kq	1900	14	of	of	IN
cord-010027-r0tl01kq	1900	15	33	33	CD
cord-010027-r0tl01kq	1900	16	)	)	-RRB-
cord-010027-r0tl01kq	1900	17	and	and	CC
cord-010027-r0tl01kq	1900	18	close	close	VB
cord-010027-r0tl01kq	1900	19	in	in	IN
cord-010027-r0tl01kq	1900	20	6	6	CD
cord-010027-r0tl01kq	1900	21	%	%	NN
cord-010027-r0tl01kq	1900	22	(	(	-LRB-
cord-010027-r0tl01kq	1900	23	2	2	CD
cord-010027-r0tl01kq	1900	24	of	of	IN
cord-010027-r0tl01kq	1900	25	33	33	CD
cord-010027-r0tl01kq	1900	26	)	)	-RRB-
cord-010027-r0tl01kq	1901	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1901	2	:	:	:
cord-010027-r0tl01kq	1902	1	Although	although	IN
cord-010027-r0tl01kq	1902	2	complete	complete	JJ
cord-010027-r0tl01kq	1902	3	excision	excision	NN
cord-010027-r0tl01kq	1902	4	is	be	VBZ
cord-010027-r0tl01kq	1902	5	more	more	RBR
cord-010027-r0tl01kq	1902	6	frequently	frequently	RB
cord-010027-r0tl01kq	1902	7	observed	observe	VBN
cord-010027-r0tl01kq	1902	8	when	when	WRB
cord-010027-r0tl01kq	1902	9	CKC	CKC	NNP
cord-010027-r0tl01kq	1902	10	is	be	VBZ
cord-010027-r0tl01kq	1902	11	performed	perform	VBN
cord-010027-r0tl01kq	1902	12	,	,	,
cord-010027-r0tl01kq	1902	13	compared	compare	VBN
cord-010027-r0tl01kq	1902	14	to	to	IN
cord-010027-r0tl01kq	1902	15	LLETZ	LLETZ	NNP
cord-010027-r0tl01kq	1902	16	,	,	,
cord-010027-r0tl01kq	1902	17	for	for	IN
cord-010027-r0tl01kq	1902	18	the	the	DT
cord-010027-r0tl01kq	1902	19	treatment	treatment	NN
cord-010027-r0tl01kq	1902	20	of	of	IN
cord-010027-r0tl01kq	1902	21	AIS	AIS	NNP
cord-010027-r0tl01kq	1902	22	0	0	CD
cord-010027-r0tl01kq	1902	23	%	%	NN
cord-010027-r0tl01kq	1902	24	)	)	-RRB-
cord-010027-r0tl01kq	1902	25	patients	patient	NNS
cord-010027-r0tl01kq	1902	26	,	,	,
cord-010027-r0tl01kq	1902	27	discordant	discordant	JJ
cord-010027-r0tl01kq	1902	28	low	low	JJ
cord-010027-r0tl01kq	1902	29	-	-	HYPH
cord-010027-r0tl01kq	1902	30	grade	grade	NN
cord-010027-r0tl01kq	1902	31	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1902	32	was	be	VBD
cord-010027-r0tl01kq	1902	33	identified	identify	VBN
cord-010027-r0tl01kq	1902	34	in	in	IN
cord-010027-r0tl01kq	1902	35	the	the	DT
cord-010027-r0tl01kq	1902	36	bone	bone	NN
cord-010027-r0tl01kq	1902	37	marrow	marrow	NN
cord-010027-r0tl01kq	1902	38	during	during	IN
cord-010027-r0tl01kq	1902	39	staging	stage	VBG
cord-010027-r0tl01kq	1902	40	investigations	investigation	NNS
cord-010027-r0tl01kq	1902	41	.	.	.
cord-010027-r0tl01kq	1903	1	4	4	LS
cord-010027-r0tl01kq	1903	2	were	be	VBD
cord-010027-r0tl01kq	1903	3	classified	classify	VBN
cord-010027-r0tl01kq	1903	4	as	as	IN
cord-010027-r0tl01kq	1903	5	Follicular	Follicular	NNP
cord-010027-r0tl01kq	1903	6	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1903	7	,	,	,
cord-010027-r0tl01kq	1903	8	2	2	CD
cord-010027-r0tl01kq	1903	9	Marginal	Marginal	NNP
cord-010027-r0tl01kq	1903	10	Zone	Zone	NNP
cord-010027-r0tl01kq	1903	11	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1903	12	,	,	,
cord-010027-r0tl01kq	1903	13	2	2	CD
cord-010027-r0tl01kq	1903	14	Chronic	chronic	NN
cord-010027-r0tl01kq	1903	15	Lymphocytic	lymphocytic	JJ
cord-010027-r0tl01kq	1903	16	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1903	17	,	,	,
cord-010027-r0tl01kq	1903	18	1	1	CD
cord-010027-r0tl01kq	1903	19	Lymphoplasmacytic	Lymphoplasmacytic	NNP
cord-010027-r0tl01kq	1903	20	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1903	21	,	,	,
cord-010027-r0tl01kq	1903	22	1	1	CD
cord-010027-r0tl01kq	1903	23	Non	Non	NNP
cord-010027-r0tl01kq	1903	24	CLL	CLL	NNP
cord-010027-r0tl01kq	1903	25	-like	-like	NNP
cord-010027-r0tl01kq	1903	26	Monoclonal	Monoclonal	NNP
cord-010027-r0tl01kq	1903	27	B	b	NN
cord-010027-r0tl01kq	1903	28	-	-	HYPH
cord-010027-r0tl01kq	1903	29	cell	cell	NN
cord-010027-r0tl01kq	1903	30	Lymphocytosis	Lymphocytosis	NNP
cord-010027-r0tl01kq	1903	31	.	.	.
cord-010027-r0tl01kq	1904	1	Five	five	CD
cord-010027-r0tl01kq	1904	2	had	have	VBD
cord-010027-r0tl01kq	1904	3	an	an	DT
cord-010027-r0tl01kq	1904	4	accompanying	accompany	VBG
cord-010027-r0tl01kq	1904	5	a	a	DT
cord-010027-r0tl01kq	1904	6	low	low	JJ
cord-010027-r0tl01kq	1904	7	-	-	HYPH
cord-010027-r0tl01kq	1904	8	grade	grade	NN
cord-010027-r0tl01kq	1904	9	component	component	NN
cord-010027-r0tl01kq	1904	10	that	that	WDT
cord-010027-r0tl01kq	1904	11	could	could	MD
cord-010027-r0tl01kq	1904	12	not	not	RB
cord-010027-r0tl01kq	1904	13	be	be	VB
cord-010027-r0tl01kq	1904	14	classified	classify	VBN
cord-010027-r0tl01kq	1904	15	.	.	.
cord-010027-r0tl01kq	1905	1	None	none	NN
cord-010027-r0tl01kq	1905	2	of	of	IN
cord-010027-r0tl01kq	1905	3	the	the	DT
cord-010027-r0tl01kq	1905	4	transformed	transform	VBN
cord-010027-r0tl01kq	1905	5	high	high	JJ
cord-010027-r0tl01kq	1905	6	-	-	HYPH
cord-010027-r0tl01kq	1905	7	grade	grade	NN
cord-010027-r0tl01kq	1905	8	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1905	9	cases	case	NNS
cord-010027-r0tl01kq	1905	10	were	be	VBD
cord-010027-r0tl01kq	1905	11	EBV	EBV	NNP
cord-010027-r0tl01kq	1905	12	positive	positive	JJ
cord-010027-r0tl01kq	1905	13	.	.	.
cord-010027-r0tl01kq	1906	1	In	in	IN
cord-010027-r0tl01kq	1906	2	our	-PRON-	PRP$
cord-010027-r0tl01kq	1906	3	cohort	cohort	NN
cord-010027-r0tl01kq	1906	4	,	,	,
cord-010027-r0tl01kq	1906	5	we	-PRON-	PRP
cord-010027-r0tl01kq	1906	6	did	do	VBD
cord-010027-r0tl01kq	1906	7	not	not	RB
cord-010027-r0tl01kq	1906	8	observe	observe	VB
cord-010027-r0tl01kq	1906	9	statistically	statistically	RB
cord-010027-r0tl01kq	1906	10	significant	significant	JJ
cord-010027-r0tl01kq	1906	11	difference	difference	NN
cord-010027-r0tl01kq	1906	12	in	in	IN
cord-010027-r0tl01kq	1906	13	survival	survival	NN
cord-010027-r0tl01kq	1906	14	between	between	IN
cord-010027-r0tl01kq	1906	15	the	the	DT
cord-010027-r0tl01kq	1906	16	Transformed	transformed	JJ
cord-010027-r0tl01kq	1906	17	and	and	CC
cord-010027-r0tl01kq	1906	18	Non	Non	NNP
cord-010027-r0tl01kq	1906	19	-	-	JJ
cord-010027-r0tl01kq	1906	20	Transformed	transformed	JJ
cord-010027-r0tl01kq	1906	21	cases	case	NNS
cord-010027-r0tl01kq	1906	22	.	.	.
cord-010027-r0tl01kq	1907	1	An	an	DT
cord-010027-r0tl01kq	1907	2	equal	equal	JJ
cord-010027-r0tl01kq	1907	3	proportion	proportion	NN
cord-010027-r0tl01kq	1907	4	of	of	IN
cord-010027-r0tl01kq	1907	5	cases	case	NNS
cord-010027-r0tl01kq	1907	6	transformed	transform	VBN
cord-010027-r0tl01kq	1907	7	from	from	IN
cord-010027-r0tl01kq	1907	8	Follicular	Follicular	NNP
cord-010027-r0tl01kq	1907	9	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1907	10	and	and	CC
cord-010027-r0tl01kq	1907	11	Marginal	Marginal	NNP
cord-010027-r0tl01kq	1907	12	Zone	Zone	NNP
cord-010027-r0tl01kq	1907	13	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1907	14	.	.	.
cord-010027-r0tl01kq	1908	1	19.1	19.1	CD
cord-010027-r0tl01kq	1908	2	%	%	NN
cord-010027-r0tl01kq	1908	3	of	of	IN
cord-010027-r0tl01kq	1908	4	Transformed	transform	VBN
cord-010027-r0tl01kq	1908	5	patients	patient	NNS
cord-010027-r0tl01kq	1908	6	had	have	VBD
cord-010027-r0tl01kq	1908	7	a	a	DT
cord-010027-r0tl01kq	1908	8	previous	previous	JJ
cord-010027-r0tl01kq	1908	9	history	history	NN
cord-010027-r0tl01kq	1908	10	of	of	IN
cord-010027-r0tl01kq	1908	11	another	another	DT
cord-010027-r0tl01kq	1908	12	cancer	cancer	NN
cord-010027-r0tl01kq	1908	13	,	,	,
cord-010027-r0tl01kq	1908	14	compared	compare	VBN
cord-010027-r0tl01kq	1908	15	to	to	IN
cord-010027-r0tl01kq	1908	16	12.1	12.1	CD
cord-010027-r0tl01kq	1908	17	%	%	NN
cord-010027-r0tl01kq	1908	18	of	of	IN
cord-010027-r0tl01kq	1908	19	Non	Non	NNP
cord-010027-r0tl01kq	1908	20	-	-	JJ
cord-010027-r0tl01kq	1908	21	Transformed	transform	VBN
cord-010027-r0tl01kq	1908	22	cases	case	NNS
cord-010027-r0tl01kq	1908	23	.	.	.
cord-010027-r0tl01kq	1909	1	Age	age	NN
cord-010027-r0tl01kq	1909	2	,	,	,
cord-010027-r0tl01kq	1909	3	gender	gender	NN
cord-010027-r0tl01kq	1909	4	and	and	CC
cord-010027-r0tl01kq	1909	5	a	a	DT
cord-010027-r0tl01kq	1909	6	history	history	NN
cord-010027-r0tl01kq	1909	7	of	of	IN
cord-010027-r0tl01kq	1909	8	autoimmune	autoimmune	JJ
cord-010027-r0tl01kq	1909	9	disease	disease	NN
cord-010027-r0tl01kq	1909	10	were	be	VBD
cord-010027-r0tl01kq	1909	11	not	not	RB
cord-010027-r0tl01kq	1909	12	associated	associate	VBN
cord-010027-r0tl01kq	1909	13	with	with	IN
cord-010027-r0tl01kq	1909	14	transformation	transformation	NN
cord-010027-r0tl01kq	1909	15	.	.	.
cord-010027-r0tl01kq	1910	1	Transformed	transform	VBN
cord-010027-r0tl01kq	1910	2	Chronic	Chronic	NNP
cord-010027-r0tl01kq	1910	3	Lymphocytic	lymphocytic	JJ
cord-010027-r0tl01kq	1910	4	Lymphoma	Lymphoma	NNP
cord-010027-r0tl01kq	1910	5	An	An	NNP
cord-010027-r0tl01kq	1910	6	Investigation	Investigation	NNP
cord-010027-r0tl01kq	1910	7	Into	into	IN
cord-010027-r0tl01kq	1910	8	the	the	DT
cord-010027-r0tl01kq	1910	9	Presentation	Presentation	NNP
cord-010027-r0tl01kq	1910	10	and	and	CC
cord-010027-r0tl01kq	1910	11	Nature	Nature	NNP
cord-010027-r0tl01kq	1910	12	of	of	IN
cord-010027-r0tl01kq	1910	13	Diffuse	diffuse	JJ
cord-010027-r0tl01kq	1910	14	Large	large	JJ
cord-010027-r0tl01kq	1910	15	B	b	NN
cord-010027-r0tl01kq	1910	16	Cell	cell	NN
cord-010027-r0tl01kq	1910	17	Lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1910	18	Within	within	IN
cord-010027-r0tl01kq	1910	19	a	a	DT
cord-010027-r0tl01kq	1910	20	Large	large	JJ
cord-010027-r0tl01kq	1910	21	Patient	Patient	NNP
cord-010027-r0tl01kq	1910	22	Cohort	Cohort	NNP
cord-010027-r0tl01kq	1910	23	P	p	NN
cord-010027-r0tl01kq	1910	24	HR	HR	NNP
cord-010027-r0tl01kq	1910	25	Freer	free	JJR
cord-010027-r0tl01kq	1910	26	1	1	CD
cord-010027-r0tl01kq	1910	27	T	T	NNP
cord-010027-r0tl01kq	1910	28	Cell	Cell	NNP
cord-010027-r0tl01kq	1910	29	/	/	SYM
cord-010027-r0tl01kq	1910	30	Histoiocyte	Histoiocyte	NNP
cord-010027-r0tl01kq	1910	31	-	-	HYPH
cord-010027-r0tl01kq	1910	32	Rich	Rich	NNP
cord-010027-r0tl01kq	1910	33	Large	large	JJ
cord-010027-r0tl01kq	1910	34	B	b	NN
cord-010027-r0tl01kq	1910	35	Cell	cell	NN
cord-010027-r0tl01kq	1910	36	Lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1910	37	(	(	-LRB-
cord-010027-r0tl01kq	1910	38	4.2	4.2	CD
cord-010027-r0tl01kq	1910	39	%	%	NN
cord-010027-r0tl01kq	1910	40	)	)	-RRB-
cord-010027-r0tl01kq	1910	41	was	be	VBD
cord-010027-r0tl01kq	1910	42	the	the	DT
cord-010027-r0tl01kq	1910	43	next	next	JJ
cord-010027-r0tl01kq	1910	44	most	most	RBS
cord-010027-r0tl01kq	1910	45	common	common	JJ
cord-010027-r0tl01kq	1910	46	subtype	subtype	NN
cord-010027-r0tl01kq	1910	47	,	,	,
cord-010027-r0tl01kq	1910	48	followed	follow	VBN
cord-010027-r0tl01kq	1910	49	by	by	IN
cord-010027-r0tl01kq	1910	50	Primary	primary	JJ
cord-010027-r0tl01kq	1910	51	DLBCL	DLBCL	NNP
cord-010027-r0tl01kq	1910	52	of	of	IN
cord-010027-r0tl01kq	1910	53	the	the	DT
cord-010027-r0tl01kq	1910	54	CNS	CNS	NNP
cord-010027-r0tl01kq	1910	55	(	(	-LRB-
cord-010027-r0tl01kq	1910	56	3.0	3.0	CD
cord-010027-r0tl01kq	1910	57	%	%	NN
cord-010027-r0tl01kq	1910	58	)	)	-RRB-
cord-010027-r0tl01kq	1910	59	.	.	.
cord-010027-r0tl01kq	1911	1	A	a	DT
cord-010027-r0tl01kq	1911	2	modified	modified	JJ
cord-010027-r0tl01kq	1911	3	R	r	NN
cord-010027-r0tl01kq	1911	4	-	-	HYPH
cord-010027-r0tl01kq	1911	5	IPI	IPI	NNP
cord-010027-r0tl01kq	1911	6	(	(	-LRB-
cord-010027-r0tl01kq	1911	7	the	the	DT
cord-010027-r0tl01kq	1911	8	patient	patient	JJ
cord-010027-r0tl01kq	1911	9	performance	performance	NN
cord-010027-r0tl01kq	1911	10	score	score	NN
cord-010027-r0tl01kq	1911	11	was	be	VBD
cord-010027-r0tl01kq	1911	12	unknown	unknown	JJ
cord-010027-r0tl01kq	1911	13	)	)	-RRB-
cord-010027-r0tl01kq	1911	14	was	be	VBD
cord-010027-r0tl01kq	1911	15	used	use	VBN
cord-010027-r0tl01kq	1911	16	to	to	TO
cord-010027-r0tl01kq	1911	17	stratify	stratify	VB
cord-010027-r0tl01kq	1911	18	the	the	DT
cord-010027-r0tl01kq	1911	19	patients	patient	NNS
cord-010027-r0tl01kq	1911	20	into	into	IN
cord-010027-r0tl01kq	1911	21	four	four	CD
cord-010027-r0tl01kq	1911	22	risk	risk	NN
cord-010027-r0tl01kq	1911	23	groups	group	NNS
cord-010027-r0tl01kq	1911	24	and	and	CC
cord-010027-r0tl01kq	1911	25	was	be	VBD
cord-010027-r0tl01kq	1911	26	found	find	VBN
cord-010027-r0tl01kq	1911	27	to	to	TO
cord-010027-r0tl01kq	1911	28	be	be	VB
cord-010027-r0tl01kq	1911	29	predictive	predictive	JJ
cord-010027-r0tl01kq	1911	30	of	of	IN
cord-010027-r0tl01kq	1911	31	patient	patient	JJ
cord-010027-r0tl01kq	1911	32	outcome	outcome	NN
cord-010027-r0tl01kq	1911	33	.	.	.
cord-010027-r0tl01kq	1912	1	The	the	DT
cord-010027-r0tl01kq	1912	2	average	average	JJ
cord-010027-r0tl01kq	1912	3	LDH	LDH	NNP
cord-010027-r0tl01kq	1912	4	level	level	NN
cord-010027-r0tl01kq	1912	5	was	be	VBD
cord-010027-r0tl01kq	1912	6	733.5	733.5	CD
cord-010027-r0tl01kq	1912	7	IU	IU	NNP
cord-010027-r0tl01kq	1912	8	/	/	SYM
cord-010027-r0tl01kq	1912	9	L	L	NNP
cord-010027-r0tl01kq	1912	10	,	,	,
cord-010027-r0tl01kq	1912	11	well	well	RB
cord-010027-r0tl01kq	1912	12	above	above	IN
cord-010027-r0tl01kq	1912	13	480	480	CD
cord-010027-r0tl01kq	1912	14	,	,	,
cord-010027-r0tl01kq	1912	15	the	the	DT
cord-010027-r0tl01kq	1912	16	upper	upper	JJ
cord-010027-r0tl01kq	1912	17	limit	limit	NN
cord-010027-r0tl01kq	1912	18	of	of	IN
cord-010027-r0tl01kq	1912	19	the	the	DT
cord-010027-r0tl01kq	1912	20	normal	normal	JJ
cord-010027-r0tl01kq	1912	21	range	range	NN
cord-010027-r0tl01kq	1912	22	.	.	.
cord-010027-r0tl01kq	1913	1	Of	of	IN
cord-010027-r0tl01kq	1913	2	the	the	DT
cord-010027-r0tl01kq	1913	3	cohort	cohort	NN
cord-010027-r0tl01kq	1913	4	of	of	IN
cord-010027-r0tl01kq	1913	5	patients	patient	NNS
cord-010027-r0tl01kq	1913	6	,	,	,
cord-010027-r0tl01kq	1913	7	52.8	52.8	CD
cord-010027-r0tl01kq	1913	8	%	%	NN
cord-010027-r0tl01kq	1913	9	achieved	achieve	VBD
cord-010027-r0tl01kq	1913	10	remission	remission	NN
cord-010027-r0tl01kq	1913	11	,	,	,
cord-010027-r0tl01kq	1913	12	15.5	15.5	CD
cord-010027-r0tl01kq	1913	13	%	%	NN
cord-010027-r0tl01kq	1913	14	were	be	VBD
cord-010027-r0tl01kq	1913	15	alive	alive	JJ
cord-010027-r0tl01kq	1913	16	with	with	IN
cord-010027-r0tl01kq	1913	17	disease	disease	NN
cord-010027-r0tl01kq	1913	18	at	at	IN
cord-010027-r0tl01kq	1913	19	the	the	DT
cord-010027-r0tl01kq	1913	20	end	end	NN
cord-010027-r0tl01kq	1913	21	of	of	IN
cord-010027-r0tl01kq	1913	22	the	the	DT
cord-010027-r0tl01kq	1913	23	study	study	NN
cord-010027-r0tl01kq	1913	24	and	and	CC
cord-010027-r0tl01kq	1913	25	31.7	31.7	CD
cord-010027-r0tl01kq	1913	26	%	%	NN
cord-010027-r0tl01kq	1913	27	are	be	VBP
cord-010027-r0tl01kq	1913	28	now	now	RB
cord-010027-r0tl01kq	1913	29	deceased	deceased	JJ
cord-010027-r0tl01kq	1913	30	.	.	.
cord-010027-r0tl01kq	1914	1	The	the	DT
cord-010027-r0tl01kq	1914	2	majority	majority	NN
cord-010027-r0tl01kq	1914	3	of	of	IN
cord-010027-r0tl01kq	1914	4	patients	patient	NNS
cord-010027-r0tl01kq	1914	5	that	that	WDT
cord-010027-r0tl01kq	1914	6	did	do	VBD
cord-010027-r0tl01kq	1914	7	die	die	VB
cord-010027-r0tl01kq	1914	8	did	do	VBD
cord-010027-r0tl01kq	1914	9	so	so	RB
cord-010027-r0tl01kq	1914	10	within	within	IN
cord-010027-r0tl01kq	1914	11	a	a	DT
cord-010027-r0tl01kq	1914	12	year	year	NN
cord-010027-r0tl01kq	1914	13	of	of	IN
cord-010027-r0tl01kq	1914	14	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1914	15	.	.	.
cord-010027-r0tl01kq	1915	1	In	in	IN
cord-010027-r0tl01kq	1915	2	addition	addition	NN
cord-010027-r0tl01kq	1915	3	,	,	,
cord-010027-r0tl01kq	1915	4	27	27	CD
cord-010027-r0tl01kq	1915	5	Bcl-2	Bcl-2	NNP
cord-010027-r0tl01kq	1915	6	negative	negative	JJ
cord-010027-r0tl01kq	1915	7	patients	patient	NNS
cord-010027-r0tl01kq	1915	8	were	be	VBD
cord-010027-r0tl01kq	1915	9	identified	identify	VBN
cord-010027-r0tl01kq	1915	10	,	,	,
cord-010027-r0tl01kq	1915	11	with	with	IN
cord-010027-r0tl01kq	1915	12	a	a	DT
cord-010027-r0tl01kq	1915	13	mean	mean	JJ
cord-010027-r0tl01kq	1915	14	age	age	NN
cord-010027-r0tl01kq	1915	15	at	at	IN
cord-010027-r0tl01kq	1915	16	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1915	17	of	of	IN
cord-010027-r0tl01kq	1915	18	66.8	66.8	CD
cord-010027-r0tl01kq	1915	19	years	year	NNS
cord-010027-r0tl01kq	1915	20	.	.	.
cord-010027-r0tl01kq	1916	1	11	11	CD
cord-010027-r0tl01kq	1916	2	of	of	IN
cord-010027-r0tl01kq	1916	3	these	these	DT
cord-010027-r0tl01kq	1916	4	patients	patient	NNS
cord-010027-r0tl01kq	1916	5	were	be	VBD
cord-010027-r0tl01kq	1916	6	female	female	JJ
cord-010027-r0tl01kq	1916	7	and	and	CC
cord-010027-r0tl01kq	1916	8	16	16	CD
cord-010027-r0tl01kq	1916	9	male	male	NN
cord-010027-r0tl01kq	1916	10	.	.	.
cord-010027-r0tl01kq	1917	1	The	the	DT
cord-010027-r0tl01kq	1917	2	mean	mean	JJ
cord-010027-r0tl01kq	1917	3	LDH	LDH	NNP
cord-010027-r0tl01kq	1917	4	level	level	NN
cord-010027-r0tl01kq	1917	5	was	be	VBD
cord-010027-r0tl01kq	1917	6	747	747	CD
cord-010027-r0tl01kq	1918	1	Some	some	DT
cord-010027-r0tl01kq	1918	2	researchers	researcher	NNS
cord-010027-r0tl01kq	1918	3	included	include	VBD
cord-010027-r0tl01kq	1918	4	additional	additional	JJ
cord-010027-r0tl01kq	1918	5	clinical	clinical	JJ
cord-010027-r0tl01kq	1918	6	features	feature	NNS
cord-010027-r0tl01kq	1918	7	that	that	WDT
cord-010027-r0tl01kq	1918	8	were	be	VBD
cord-010027-r0tl01kq	1918	9	common	common	JJ
cord-010027-r0tl01kq	1918	10	when	when	WRB
cord-010027-r0tl01kq	1918	11	there	there	EX
cord-010027-r0tl01kq	1918	12	was	be	VBD
cord-010027-r0tl01kq	1918	13	malignancy	malignancy	NN
cord-010027-r0tl01kq	1918	14	in	in	IN
cord-010027-r0tl01kq	1918	15	the	the	DT
cord-010027-r0tl01kq	1918	16	asymmetrical	asymmetrical	JJ
cord-010027-r0tl01kq	1918	17	tonsils	tonsil	NNS
cord-010027-r0tl01kq	1918	18	.	.	.
cord-010027-r0tl01kq	1919	1	In	in	IN
cord-010027-r0tl01kq	1919	2	this	this	DT
cord-010027-r0tl01kq	1919	3	study	study	NN
cord-010027-r0tl01kq	1919	4	we	-PRON-	PRP
cord-010027-r0tl01kq	1919	5	aim	aim	VBP
cord-010027-r0tl01kq	1919	6	to	to	TO
cord-010027-r0tl01kq	1919	7	evaluate	evaluate	VB
cord-010027-r0tl01kq	1919	8	the	the	DT
cord-010027-r0tl01kq	1919	9	cancer	cancer	NN
cord-010027-r0tl01kq	1919	10	detection	detection	NN
cord-010027-r0tl01kq	1919	11	rate	rate	NN
cord-010027-r0tl01kq	1919	12	in	in	IN
cord-010027-r0tl01kq	1919	13	this	this	DT
cord-010027-r0tl01kq	1919	14	setting	setting	NN
cord-010027-r0tl01kq	1919	15	including	include	VBG
cord-010027-r0tl01kq	1919	16	those	those	DT
cord-010027-r0tl01kq	1919	17	who	who	WP
cord-010027-r0tl01kq	1919	18	possess	possess	VBP
cord-010027-r0tl01kq	1919	19	high	high	JJ
cord-010027-r0tl01kq	1919	20	risk	risk	NN
cord-010027-r0tl01kq	1919	21	clinical	clinical	JJ
cord-010027-r0tl01kq	1919	22	features	feature	NNS
cord-010027-r0tl01kq	1919	23	such	such	JJ
cord-010027-r0tl01kq	1919	24	as	as	IN
cord-010027-r0tl01kq	1919	25	age	age	NN
cord-010027-r0tl01kq	1919	26	(	(	-LRB-
cord-010027-r0tl01kq	1919	27	>	>	NFP
cord-010027-r0tl01kq	1919	28	45	45	CD
cord-010027-r0tl01kq	1919	29	)	)	-RRB-
cord-010027-r0tl01kq	1919	30	,	,	,
cord-010027-r0tl01kq	1919	31	pain	pain	NN
cord-010027-r0tl01kq	1919	32	and	and	CC
cord-010027-r0tl01kq	1919	33	history	history	NN
cord-010027-r0tl01kq	1919	34	of	of	IN
cord-010027-r0tl01kq	1919	35	smoking	smoking	NN
cord-010027-r0tl01kq	1919	36	.	.	.
cord-010027-r0tl01kq	1920	1	Methodology	methodology	NN
cord-010027-r0tl01kq	1920	2	:	:	:
cord-010027-r0tl01kq	1921	1	In	in	IN
cord-010027-r0tl01kq	1921	2	total	total	JJ
cord-010027-r0tl01kq	1921	3	,	,	,
cord-010027-r0tl01kq	1921	4	119	119	CD
cord-010027-r0tl01kq	1921	5	consecutive	consecutive	JJ
cord-010027-r0tl01kq	1921	6	tonsillectomy	tonsillectomy	NN
cord-010027-r0tl01kq	1921	7	cases	case	NNS
cord-010027-r0tl01kq	1921	8	,	,	,
cord-010027-r0tl01kq	1921	9	clinically	clinically	RB
cord-010027-r0tl01kq	1921	10	labelled	label	VBN
cord-010027-r0tl01kq	1921	11	as	as	IN
cord-010027-r0tl01kq	1921	12	asymmetrical	asymmetrical	JJ
cord-010027-r0tl01kq	1921	13	tonsils	tonsil	NNS
cord-010027-r0tl01kq	1921	14	were	be	VBD
cord-010027-r0tl01kq	1921	15	analysed	analyse	VBN
cord-010027-r0tl01kq	1921	16	.	.	.
cord-010027-r0tl01kq	1922	1	Out	out	IN
cord-010027-r0tl01kq	1922	2	of	of	IN
cord-010027-r0tl01kq	1922	3	these	these	DT
cord-010027-r0tl01kq	1922	4	,	,	,
cord-010027-r0tl01kq	1922	5	28	28	CD
cord-010027-r0tl01kq	1922	6	cases	case	NNS
cord-010027-r0tl01kq	1922	7	(	(	-LRB-
cord-010027-r0tl01kq	1922	8	Group	group	NN
cord-010027-r0tl01kq	1922	9	1	1	CD
cord-010027-r0tl01kq	1922	10	)	)	-RRB-
cord-010027-r0tl01kq	1922	11	were	be	VBD
cord-010027-r0tl01kq	1922	12	additionally	additionally	RB
cord-010027-r0tl01kq	1922	13	labelled	label	VBN
cord-010027-r0tl01kq	1922	14	with	with	IN
cord-010027-r0tl01kq	1922	15	investigation	investigation	NN
cord-010027-r0tl01kq	1922	16	for	for	IN
cord-010027-r0tl01kq	1922	17	unknown	unknown	JJ
cord-010027-r0tl01kq	1922	18	primary	primary	JJ
cord-010027-r0tl01kq	1922	19	,	,	,
cord-010027-r0tl01kq	1922	20	obvious	obvious	JJ
cord-010027-r0tl01kq	1922	21	lesion	lesion	NN
cord-010027-r0tl01kq	1922	22	or	or	CC
cord-010027-r0tl01kq	1922	23	suspicious	suspicious	JJ
cord-010027-r0tl01kq	1922	24	ulcer	ulcer	NN
cord-010027-r0tl01kq	1922	25	seen	see	VBN
cord-010027-r0tl01kq	1922	26	.	.	.
cord-010027-r0tl01kq	1923	1	The	the	DT
cord-010027-r0tl01kq	1923	2	remaining	remain	VBG
cord-010027-r0tl01kq	1923	3	91	91	CD
cord-010027-r0tl01kq	1923	4	cases	case	NNS
cord-010027-r0tl01kq	1923	5	with	with	IN
cord-010027-r0tl01kq	1923	6	a	a	DT
cord-010027-r0tl01kq	1923	7	sole	sole	JJ
cord-010027-r0tl01kq	1923	8	clinical	clinical	JJ
cord-010027-r0tl01kq	1923	9	indication	indication	NN
cord-010027-r0tl01kq	1923	10	of	of	IN
cord-010027-r0tl01kq	1923	11	asymmetry	asymmetry	NN
cord-010027-r0tl01kq	1923	12	were	be	VBD
cord-010027-r0tl01kq	1923	13	stratified	stratify	VBN
cord-010027-r0tl01kq	1923	14	as	as	IN
cord-010027-r0tl01kq	1923	15	group	group	NN
cord-010027-r0tl01kq	1923	16	2	2	CD
cord-010027-r0tl01kq	1923	17	.	.	.
cord-010027-r0tl01kq	1924	1	Results	result	NNS
cord-010027-r0tl01kq	1924	2	:	:	:
cord-010027-r0tl01kq	1925	1	In	in	IN
cord-010027-r0tl01kq	1925	2	the	the	DT
cord-010027-r0tl01kq	1925	3	first	first	JJ
cord-010027-r0tl01kq	1925	4	group	group	NN
cord-010027-r0tl01kq	1925	5	,	,	,
cord-010027-r0tl01kq	1925	6	7	7	CD
cord-010027-r0tl01kq	1925	7	cases	case	NNS
cord-010027-r0tl01kq	1925	8	had	have	VBD
cord-010027-r0tl01kq	1925	9	a	a	DT
cord-010027-r0tl01kq	1925	10	histological	histological	JJ
cord-010027-r0tl01kq	1925	11	confirmation	confirmation	NN
cord-010027-r0tl01kq	1925	12	of	of	IN
cord-010027-r0tl01kq	1925	13	tonsillar	tonsillar	JJ
cord-010027-r0tl01kq	1925	14	primary	primary	NN
cord-010027-r0tl01kq	1925	15	(	(	-LRB-
cord-010027-r0tl01kq	1925	16	25	25	CD
cord-010027-r0tl01kq	1925	17	%	%	NN
cord-010027-r0tl01kq	1925	18	)	)	-RRB-
cord-010027-r0tl01kq	1925	19	.	.	.
cord-010027-r0tl01kq	1926	1	While	while	IN
cord-010027-r0tl01kq	1926	2	,	,	,
cord-010027-r0tl01kq	1926	3	in	in	IN
cord-010027-r0tl01kq	1926	4	the	the	DT
cord-010027-r0tl01kq	1926	5	second	second	JJ
cord-010027-r0tl01kq	1926	6	group	group	NN
cord-010027-r0tl01kq	1926	7	,	,	,
cord-010027-r0tl01kq	1926	8	the	the	DT
cord-010027-r0tl01kq	1926	9	histological	histological	JJ
cord-010027-r0tl01kq	1926	10	analysis	analysis	NN
cord-010027-r0tl01kq	1926	11	showed	show	VBD
cord-010027-r0tl01kq	1926	12	78	78	CD
cord-010027-r0tl01kq	1926	13	cases	case	NNS
cord-010027-r0tl01kq	1926	14	with	with	IN
cord-010027-r0tl01kq	1926	15	benign	benign	JJ
cord-010027-r0tl01kq	1926	16	reactive	reactive	JJ
cord-010027-r0tl01kq	1926	17	pathology	pathology	NN
cord-010027-r0tl01kq	1926	18	(	(	-LRB-
cord-010027-r0tl01kq	1926	19	89	89	CD
cord-010027-r0tl01kq	1926	20	%	%	NN
cord-010027-r0tl01kq	1926	21	)	)	-RRB-
cord-010027-r0tl01kq	1926	22	while	while	IN
cord-010027-r0tl01kq	1926	23	,	,	,
cord-010027-r0tl01kq	1926	24	one	one	CD
cord-010027-r0tl01kq	1926	25	case	case	NN
cord-010027-r0tl01kq	1926	26	was	be	VBD
cord-010027-r0tl01kq	1926	27	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1926	28	as	as	IN
cord-010027-r0tl01kq	1926	29	malignant	malignant	JJ
cord-010027-r0tl01kq	1926	30	lymphoma	lymphoma	NN
cord-010027-r0tl01kq	1926	31	(	(	-LRB-
cord-010027-r0tl01kq	1926	32	1	1	CD
cord-010027-r0tl01kq	1926	33	%	%	NN
cord-010027-r0tl01kq	1926	34	)	)	-RRB-
cord-010027-r0tl01kq	1926	35	,	,	,
cord-010027-r0tl01kq	1926	36	6	6	CD
cord-010027-r0tl01kq	1926	37	cases	case	NNS
cord-010027-r0tl01kq	1926	38	with	with	IN
cord-010027-r0tl01kq	1926	39	mild	mild	JJ
cord-010027-r0tl01kq	1926	40	dysplasia	dysplasia	NN
cord-010027-r0tl01kq	1926	41	(	(	-LRB-
cord-010027-r0tl01kq	1926	42	7	7	CD
cord-010027-r0tl01kq	1926	43	%	%	NN
cord-010027-r0tl01kq	1926	44	)	)	-RRB-
cord-010027-r0tl01kq	1927	1	Conclusion	conclusion	NN
cord-010027-r0tl01kq	1927	2	:	:	:
cord-010027-r0tl01kq	1928	1	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1928	2	results	result	NNS
cord-010027-r0tl01kq	1928	3	do	do	VBP
cord-010027-r0tl01kq	1928	4	correlate	correlate	VB
cord-010027-r0tl01kq	1928	5	with	with	IN
cord-010027-r0tl01kq	1928	6	the	the	DT
cord-010027-r0tl01kq	1928	7	considerable	considerable	JJ
cord-010027-r0tl01kq	1928	8	agreement	agreement	NN
cord-010027-r0tl01kq	1928	9	amongst	amongst	IN
cord-010027-r0tl01kq	1928	10	otolaryngologists	otolaryngologist	NNS
cord-010027-r0tl01kq	1928	11	that	that	IN
cord-010027-r0tl01kq	1928	12	the	the	DT
cord-010027-r0tl01kq	1928	13	appearance	appearance	NN
cord-010027-r0tl01kq	1928	14	of	of	IN
cord-010027-r0tl01kq	1928	15	an	an	DT
cord-010027-r0tl01kq	1928	16	asymmetrically	asymmetrically	RB
cord-010027-r0tl01kq	1928	17	enlarged	enlarged	JJ
cord-010027-r0tl01kq	1928	18	tonsil	tonsil	NN
cord-010027-r0tl01kq	1928	19	in	in	IN
cord-010027-r0tl01kq	1928	20	the	the	DT
cord-010027-r0tl01kq	1928	21	presence	presence	NN
cord-010027-r0tl01kq	1928	22	of	of	IN
cord-010027-r0tl01kq	1928	23	associated	associated	JJ
cord-010027-r0tl01kq	1928	24	risk	risk	NN
cord-010027-r0tl01kq	1928	25	factors	factor	NNS
cord-010027-r0tl01kq	1928	26	is	be	VBZ
cord-010027-r0tl01kq	1928	27	considered	consider	VBN
cord-010027-r0tl01kq	1928	28	an	an	DT
cord-010027-r0tl01kq	1928	29	indication	indication	NN
cord-010027-r0tl01kq	1928	30	for	for	IN
cord-010027-r0tl01kq	1928	31	tonsillectomy	tonsillectomy	NN
cord-010027-r0tl01kq	1928	32	and	and	CC
cord-010027-r0tl01kq	1928	33	histological	histological	JJ
cord-010027-r0tl01kq	1928	34	examination	examination	NN
cord-010027-r0tl01kq	1928	35	given	give	VBN
cord-010027-r0tl01kq	1928	36	the	the	DT
cord-010027-r0tl01kq	1928	37	significant	significant	JJ
cord-010027-r0tl01kq	1928	38	rate	rate	NN
cord-010027-r0tl01kq	1928	39	of	of	IN
cord-010027-r0tl01kq	1928	40	tonsillar	tonsillar	JJ
cord-010027-r0tl01kq	1928	41	malignancies	malignancy	NNS
cord-010027-r0tl01kq	1928	42	in	in	IN
cord-010027-r0tl01kq	1928	43	this	this	DT
cord-010027-r0tl01kq	1928	44	group	group	NN
cord-010027-r0tl01kq	1928	45	.	.	.
cord-010027-r0tl01kq	1929	1	Anatomical	anatomical	JJ
cord-010027-r0tl01kq	1929	2	difference	difference	NN
cord-010027-r0tl01kq	1929	3	in	in	IN
cord-010027-r0tl01kq	1929	4	the	the	DT
cord-010027-r0tl01kq	1929	5	depth	depth	NN
cord-010027-r0tl01kq	1929	6	of	of	IN
cord-010027-r0tl01kq	1929	7	tonsillar	tonsillar	JJ
cord-010027-r0tl01kq	1929	8	fossa	fossa	NN
cord-010027-r0tl01kq	1929	9	and	and	CC
cord-010027-r0tl01kq	1929	10	asymmetry	asymmetry	NN
cord-010027-r0tl01kq	1929	11	of	of	IN
cord-010027-r0tl01kq	1929	12	the	the	DT
cord-010027-r0tl01kq	1929	13	anterior	anterior	JJ
cord-010027-r0tl01kq	1929	14	tonsillar	tonsillar	JJ
cord-010027-r0tl01kq	1929	15	pillar	pillar	NN
cord-010027-r0tl01kq	1929	16	may	may	MD
cord-010027-r0tl01kq	1929	17	give	give	VB
cord-010027-r0tl01kq	1929	18	a	a	DT
cord-010027-r0tl01kq	1929	19	false	false	JJ
cord-010027-r0tl01kq	1929	20	impression	impression	NN
cord-010027-r0tl01kq	1929	21	of	of	IN
cord-010027-r0tl01kq	1929	22	a	a	DT
cord-010027-r0tl01kq	1929	23	clinically	clinically	RB
cord-010027-r0tl01kq	1929	24	asymmetrical	asymmetrical	JJ
cord-010027-r0tl01kq	1929	25	or	or	CC
cord-010027-r0tl01kq	1929	26	unilateral	unilateral	JJ
cord-010027-r0tl01kq	1929	27	enlarged	enlarged	JJ
cord-010027-r0tl01kq	1929	28	tonsil	tonsil	NN
cord-010027-r0tl01kq	1929	29	Metastatic	Metastatic	NNP
cord-010027-r0tl01kq	1929	30	Adenoid	Adenoid	NNP
cord-010027-r0tl01kq	1929	31	Cystic	Cystic	NNP
cord-010027-r0tl01kq	1929	32	Carcinoma	Carcinoma	NNP
cord-010027-r0tl01kq	1929	33	to	to	IN
cord-010027-r0tl01kq	1929	34	the	the	DT
cord-010027-r0tl01kq	1929	35	Lung	Lung	NNP
cord-010027-r0tl01kq	1929	36	and	and	CC
cord-010027-r0tl01kq	1929	37	Kidney	kidney	NN
cord-010027-r0tl01kq	1929	38	:	:	:
cord-010027-r0tl01kq	1930	1	A	a	DT
cord-010027-r0tl01kq	1930	2	Single	Single	NNP
cord-010027-r0tl01kq	1930	3	Case	Case	NNP
cord-010027-r0tl01kq	1930	4	Report	Report	NNP
cord-010027-r0tl01kq	1930	5	P	p	NN
cord-010027-r0tl01kq	1930	6	RM	rm	NN
cord-010027-r0tl01kq	1930	7	Doyle	Doyle	NNP
cord-010027-r0tl01kq	1931	1	The	the	DT
cord-010027-r0tl01kq	1931	2	tumour	tumour	NN
cord-010027-r0tl01kq	1931	3	has	have	VBZ
cord-010027-r0tl01kq	1931	4	three	three	CD
cord-010027-r0tl01kq	1931	5	prognostically	prognostically	RB
cord-010027-r0tl01kq	1931	6	significant	significant	JJ
cord-010027-r0tl01kq	1931	7	subtypes	subtype	NNS
cord-010027-r0tl01kq	1931	8	which	which	WDT
cord-010027-r0tl01kq	1931	9	form	form	VBP
cord-010027-r0tl01kq	1931	10	the	the	DT
cord-010027-r0tl01kq	1931	11	basis	basis	NN
cord-010027-r0tl01kq	1931	12	for	for	IN
cord-010027-r0tl01kq	1931	13	tumour	tumour	NN
cord-010027-r0tl01kq	1931	14	grading	grading	NN
cord-010027-r0tl01kq	1931	15	;	;	:
cord-010027-r0tl01kq	1931	16	cribriform	cribriform	NNP
cord-010027-r0tl01kq	1931	17	,	,	,
cord-010027-r0tl01kq	1931	18	most	most	RBS
cord-010027-r0tl01kq	1931	19	frequent	frequent	JJ
cord-010027-r0tl01kq	1931	20	,	,	,
cord-010027-r0tl01kq	1931	21	tubular	tubular	JJ
cord-010027-r0tl01kq	1931	22	and	and	CC
cord-010027-r0tl01kq	1931	23	solid	solid	JJ
cord-010027-r0tl01kq	1931	24	,	,	,
cord-010027-r0tl01kq	1931	25	associated	associate	VBN
cord-010027-r0tl01kq	1931	26	with	with	IN
cord-010027-r0tl01kq	1931	27	a	a	DT
cord-010027-r0tl01kq	1931	28	more	more	RBR
cord-010027-r0tl01kq	1931	29	aggressive	aggressive	JJ
cord-010027-r0tl01kq	1931	30	clinical	clinical	JJ
cord-010027-r0tl01kq	1931	31	course	course	NN
cord-010027-r0tl01kq	1931	32	and	and	CC
cord-010027-r0tl01kq	1931	33	metastasis	metastasis	NN
cord-010027-r0tl01kq	1931	34	.	.	.
cord-010027-r0tl01kq	1932	1	In	in	IN
cord-010027-r0tl01kq	1932	2	the	the	DT
cord-010027-r0tl01kq	1932	3	majority	majority	NN
cord-010027-r0tl01kq	1932	4	of	of	IN
cord-010027-r0tl01kq	1932	5	cases	case	NNS
cord-010027-r0tl01kq	1932	6	(	(	-LRB-
cord-010027-r0tl01kq	1932	7	74	74	CD
cord-010027-r0tl01kq	1932	8	%	%	NN
cord-010027-r0tl01kq	1932	9	)	)	-RRB-
cord-010027-r0tl01kq	1932	10	the	the	DT
cord-010027-r0tl01kq	1932	11	tumour	tumour	NN
cord-010027-r0tl01kq	1932	12	has	have	VBZ
cord-010027-r0tl01kq	1932	13	an	an	DT
cord-010027-r0tl01kq	1932	14	insidious	insidious	JJ
cord-010027-r0tl01kq	1932	15	onset	onset	NN
cord-010027-r0tl01kq	1932	16	and	and	CC
cord-010027-r0tl01kq	1932	17	patients	patient	NNS
cord-010027-r0tl01kq	1932	18	have	have	VBP
cord-010027-r0tl01kq	1932	19	locally	locally	RB
cord-010027-r0tl01kq	1932	20	invasive	invasive	JJ
cord-010027-r0tl01kq	1932	21	disease	disease	NN
cord-010027-r0tl01kq	1932	22	at	at	IN
cord-010027-r0tl01kq	1932	23	first	first	JJ
cord-010027-r0tl01kq	1932	24	presentation	presentation	NN
cord-010027-r0tl01kq	1932	25	,	,	,
cord-010027-r0tl01kq	1932	26	which	which	WDT
cord-010027-r0tl01kq	1932	27	coupled	couple	VBD
cord-010027-r0tl01kq	1932	28	with	with	IN
cord-010027-r0tl01kq	1932	29	adjacent	adjacent	JJ
cord-010027-r0tl01kq	1932	30	,	,	,
cord-010027-r0tl01kq	1932	31	important	important	JJ
cord-010027-r0tl01kq	1932	32	anatomical	anatomical	JJ
cord-010027-r0tl01kq	1932	33	structures	structure	NNS
cord-010027-r0tl01kq	1932	34	means	mean	VBZ
cord-010027-r0tl01kq	1932	35	a	a	DT
cord-010027-r0tl01kq	1932	36	complete	complete	JJ
cord-010027-r0tl01kq	1932	37	primary	primary	JJ
cord-010027-r0tl01kq	1932	38	surgical	surgical	JJ
cord-010027-r0tl01kq	1932	39	resection	resection	NN
cord-010027-r0tl01kq	1932	40	is	be	VBZ
cord-010027-r0tl01kq	1932	41	often	often	RB
cord-010027-r0tl01kq	1932	42	not	not	RB
cord-010027-r0tl01kq	1932	43	feasible	feasible	JJ
cord-010027-r0tl01kq	1932	44	.	.	.
cord-010027-r0tl01kq	1933	1	Distant	distant	JJ
cord-010027-r0tl01kq	1933	2	metastases	metastasis	NNS
cord-010027-r0tl01kq	1933	3	are	be	VBP
cord-010027-r0tl01kq	1933	4	frequent	frequent	JJ
cord-010027-r0tl01kq	1933	5	and	and	CC
cord-010027-r0tl01kq	1933	6	predominately	predominately	RB
cord-010027-r0tl01kq	1933	7	involve	involve	VB
cord-010027-r0tl01kq	1933	8	the	the	DT
cord-010027-r0tl01kq	1933	9	lung	lung	NN
cord-010027-r0tl01kq	1933	10	and	and	CC
cord-010027-r0tl01kq	1933	11	bone	bone	NN
cord-010027-r0tl01kq	1933	12	with	with	IN
cord-010027-r0tl01kq	1933	13	renal	renal	JJ
cord-010027-r0tl01kq	1933	14	metastasis	metastasis	NN
cord-010027-r0tl01kq	1933	15	a	a	DT
cord-010027-r0tl01kq	1933	16	rare	rare	JJ
cord-010027-r0tl01kq	1933	17	occurrence	occurrence	NN
cord-010027-r0tl01kq	1933	18	.	.	.
cord-010027-r0tl01kq	1934	1	An	an	DT
cord-010027-r0tl01kq	1934	2	optimal	optimal	JJ
cord-010027-r0tl01kq	1934	3	treatment	treatment	NN
cord-010027-r0tl01kq	1934	4	regime	regime	NN
cord-010027-r0tl01kq	1934	5	for	for	IN
cord-010027-r0tl01kq	1934	6	ACC	ACC	NNP
cord-010027-r0tl01kq	1934	7	has	have	VBZ
cord-010027-r0tl01kq	1934	8	yet	yet	RB
cord-010027-r0tl01kq	1934	9	to	to	TO
cord-010027-r0tl01kq	1934	10	be	be	VB
cord-010027-r0tl01kq	1934	11	established	establish	VBN
cord-010027-r0tl01kq	1934	12	and	and	CC
cord-010027-r0tl01kq	1934	13	while	while	IN
cord-010027-r0tl01kq	1934	14	local	local	JJ
cord-010027-r0tl01kq	1934	15	management	management	NN
cord-010027-r0tl01kq	1934	16	with	with	IN
cord-010027-r0tl01kq	1934	17	combination	combination	NN
cord-010027-r0tl01kq	1934	18	surgery	surgery	NN
cord-010027-r0tl01kq	1934	19	and	and	CC
cord-010027-r0tl01kq	1934	20	adjuvant	adjuvant	NN
cord-010027-r0tl01kq	1934	21	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1934	22	is	be	VBZ
cord-010027-r0tl01kq	1934	23	currently	currently	RB
cord-010027-r0tl01kq	1934	24	favoured	favour	VBN
cord-010027-r0tl01kq	1934	25	there	there	EX
cord-010027-r0tl01kq	1934	26	is	be	VBZ
cord-010027-r0tl01kq	1934	27	conflicting	conflict	VBG
cord-010027-r0tl01kq	1934	28	evidence	evidence	NN
cord-010027-r0tl01kq	1934	29	regarding	regard	VBG
cord-010027-r0tl01kq	1934	30	the	the	DT
cord-010027-r0tl01kq	1934	31	use	use	NN
cord-010027-r0tl01kq	1934	32	of	of	IN
cord-010027-r0tl01kq	1934	33	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1934	34	and	and	CC
cord-010027-r0tl01kq	1934	35	no	no	DT
cord-010027-r0tl01kq	1934	36	formal	formal	JJ
cord-010027-r0tl01kq	1934	37	surveillance	surveillance	NN
cord-010027-r0tl01kq	1934	38	guidance	guidance	NN
cord-010027-r0tl01kq	1934	39	for	for	IN
cord-010027-r0tl01kq	1934	40	local	local	JJ
cord-010027-r0tl01kq	1934	41	and	and	CC
cord-010027-r0tl01kq	1934	42	regional	regional	JJ
cord-010027-r0tl01kq	1934	43	recurrence	recurrence	NN
cord-010027-r0tl01kq	1934	44	or	or	CC
cord-010027-r0tl01kq	1934	45	distant	distant	JJ
cord-010027-r0tl01kq	1934	46	metastasis	metastasis	NN
cord-010027-r0tl01kq	1934	47	exists	exist	VBZ
cord-010027-r0tl01kq	1934	48	.	.	.
cord-010027-r0tl01kq	1935	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1935	2	report	report	VBP
cord-010027-r0tl01kq	1935	3	a	a	DT
cord-010027-r0tl01kq	1935	4	single	single	JJ
cord-010027-r0tl01kq	1935	5	case	case	NN
cord-010027-r0tl01kq	1935	6	of	of	IN
cord-010027-r0tl01kq	1935	7	a	a	DT
cord-010027-r0tl01kq	1935	8	52	52	CD
cord-010027-r0tl01kq	1935	9	year	year	NN
cord-010027-r0tl01kq	1935	10	old	old	JJ
cord-010027-r0tl01kq	1935	11	male	male	NN
cord-010027-r0tl01kq	1935	12	who	who	WP
cord-010027-r0tl01kq	1935	13	presented	present	VBD
cord-010027-r0tl01kq	1935	14	in	in	IN
cord-010027-r0tl01kq	1935	15	2004	2004	CD
cord-010027-r0tl01kq	1935	16	with	with	IN
cord-010027-r0tl01kq	1935	17	an	an	DT
cord-010027-r0tl01kq	1935	18	asymptomatic	asymptomatic	JJ
cord-010027-r0tl01kq	1935	19	right	right	JJ
cord-010027-r0tl01kq	1935	20	neck	neck	NN
cord-010027-r0tl01kq	1935	21	mass	mass	NN
cord-010027-r0tl01kq	1935	22	and	and	CC
cord-010027-r0tl01kq	1935	23	underwent	undergo	VBD
cord-010027-r0tl01kq	1935	24	right	right	JJ
cord-010027-r0tl01kq	1935	25	radical	radical	JJ
cord-010027-r0tl01kq	1935	26	neck	neck	NN
cord-010027-r0tl01kq	1935	27	dissection	dissection	NN
cord-010027-r0tl01kq	1935	28	and	and	CC
cord-010027-r0tl01kq	1935	29	adjuvant	adjuvant	NN
cord-010027-r0tl01kq	1935	30	radiotherapy	radiotherapy	NN
cord-010027-r0tl01kq	1935	31	for	for	IN
cord-010027-r0tl01kq	1935	32	ACC	ACC	NNP
cord-010027-r0tl01kq	1935	33	.	.	.
cord-010027-r0tl01kq	1936	1	The	the	DT
cord-010027-r0tl01kq	1936	2	patient	patient	NN
cord-010027-r0tl01kq	1936	3	represented	represent	VBD
cord-010027-r0tl01kq	1936	4	in	in	IN
cord-010027-r0tl01kq	1936	5	2014	2014	CD
cord-010027-r0tl01kq	1936	6	with	with	IN
cord-010027-r0tl01kq	1936	7	aspiration	aspiration	NN
cord-010027-r0tl01kq	1936	8	pneumonia	pneumonia	NN
cord-010027-r0tl01kq	1936	9	on	on	IN
cord-010027-r0tl01kq	1936	10	a	a	DT
cord-010027-r0tl01kq	1936	11	seven	seven	CD
cord-010027-r0tl01kq	1936	12	month	month	NN
cord-010027-r0tl01kq	1936	13	history	history	NN
cord-010027-r0tl01kq	1936	14	of	of	IN
cord-010027-r0tl01kq	1936	15	dysphagia	dysphagia	NN
cord-010027-r0tl01kq	1936	16	and	and	CC
cord-010027-r0tl01kq	1936	17	dyspnea	dyspnea	NN
cord-010027-r0tl01kq	1936	18	.	.	.
cord-010027-r0tl01kq	1937	1	Xray	Xray	NNP
cord-010027-r0tl01kq	1937	2	and	and	CC
cord-010027-r0tl01kq	1937	3	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1937	4	computed	compute	VBN
cord-010027-r0tl01kq	1937	5	tomography	tomography	NN
cord-010027-r0tl01kq	1937	6	(	(	-LRB-
cord-010027-r0tl01kq	1937	7	CT	CT	NNP
cord-010027-r0tl01kq	1937	8	)	)	-RRB-
cord-010027-r0tl01kq	1937	9	imaging	imaging	NN
cord-010027-r0tl01kq	1937	10	identified	identify	VBD
cord-010027-r0tl01kq	1937	11	large	large	JJ
cord-010027-r0tl01kq	1937	12	,	,	,
cord-010027-r0tl01kq	1937	13	multiple	multiple	JJ
cord-010027-r0tl01kq	1937	14	right	right	JJ
cord-010027-r0tl01kq	1937	15	sided	sided	JJ
cord-010027-r0tl01kq	1937	16	lung	lung	NN
cord-010027-r0tl01kq	1937	17	lesions	lesion	NNS
cord-010027-r0tl01kq	1937	18	,	,	,
cord-010027-r0tl01kq	1937	19	maximum	maximum	JJ
cord-010027-r0tl01kq	1937	20	3	3	CD
cord-010027-r0tl01kq	1937	21	cm	cm	NN
cord-010027-r0tl01kq	1937	22	,	,	,
cord-010027-r0tl01kq	1937	23	and	and	CC
cord-010027-r0tl01kq	1937	24	a	a	DT
cord-010027-r0tl01kq	1937	25	5.6	5.6	CD
cord-010027-r0tl01kq	1937	26	cm	cm	NNS
cord-010027-r0tl01kq	1937	27	left	leave	VBN
cord-010027-r0tl01kq	1937	28	renal	renal	JJ
cord-010027-r0tl01kq	1937	29	upper	upper	JJ
cord-010027-r0tl01kq	1937	30	pole	pole	NN
cord-010027-r0tl01kq	1937	31	mass	mass	NN
cord-010027-r0tl01kq	1937	32	.	.	.
cord-010027-r0tl01kq	1938	1	CT	CT	NNP
cord-010027-r0tl01kq	1938	2	guided	guide	VBD
cord-010027-r0tl01kq	1938	3	biopsy	biopsy	NN
cord-010027-r0tl01kq	1938	4	of	of	IN
cord-010027-r0tl01kq	1938	5	the	the	DT
cord-010027-r0tl01kq	1938	6	right	right	JJ
cord-010027-r0tl01kq	1938	7	lung	lung	NN
cord-010027-r0tl01kq	1938	8	lesion	lesion	NN
cord-010027-r0tl01kq	1938	9	and	and	CC
cord-010027-r0tl01kq	1938	10	ultrasound	ultrasound	NN
cord-010027-r0tl01kq	1938	11	guided	guide	VBN
cord-010027-r0tl01kq	1938	12	biopsy	biopsy	NN
cord-010027-r0tl01kq	1938	13	of	of	IN
cord-010027-r0tl01kq	1938	14	the	the	DT
cord-010027-r0tl01kq	1938	15	renal	renal	JJ
cord-010027-r0tl01kq	1938	16	mass	mass	NN
cord-010027-r0tl01kq	1938	17	were	be	VBD
cord-010027-r0tl01kq	1938	18	reported	report	VBN
cord-010027-r0tl01kq	1938	19	as	as	IN
cord-010027-r0tl01kq	1938	20	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1938	21	adenoid	adenoid	NN
cord-010027-r0tl01kq	1938	22	cystic	cystic	JJ
cord-010027-r0tl01kq	1938	23	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1938	24	Regan	Regan	NNP
cord-010027-r0tl01kq	1938	25	3	3	CD
cord-010027-r0tl01kq	1938	26	;	;	:
cord-010027-r0tl01kq	1938	27	CM	CM	NNP
cord-010027-r0tl01kq	1938	28	Martin	Martin	NNP
cord-010027-r0tl01kq	1938	29	2	2	CD
cord-010027-r0tl01kq	1938	30	;	;	:
cord-010027-r0tl01kq	1938	31	CV	CV	NNP
cord-010027-r0tl01kq	1938	32	Timon	Timon	NNP
cord-010027-r0tl01kq	1938	33	3	3	CD
cord-010027-r0tl01kq	1938	34	Cytokeratin	Cytokeratin	NNP
cord-010027-r0tl01kq	1938	35	7	7	CD
cord-010027-r0tl01kq	1938	36	(	(	-LRB-
cord-010027-r0tl01kq	1938	37	CK7	CK7	NNP
cord-010027-r0tl01kq	1938	38	)	)	-RRB-
cord-010027-r0tl01kq	1938	39	is	be	VBZ
cord-010027-r0tl01kq	1938	40	a	a	DT
cord-010027-r0tl01kq	1938	41	junctional	junctional	JJ
cord-010027-r0tl01kq	1938	42	biomarker	biomarker	NN
cord-010027-r0tl01kq	1938	43	with	with	IN
cord-010027-r0tl01kq	1938	44	a	a	DT
cord-010027-r0tl01kq	1938	45	SEQIKA	SEQIKA	NNP
cord-010027-r0tl01kq	1938	46	fragment	fragment	NN
cord-010027-r0tl01kq	1938	47	which	which	WDT
cord-010027-r0tl01kq	1938	48	stabilises	stabilise	VBZ
cord-010027-r0tl01kq	1938	49	HPV-16	HPV-16	NNP
cord-010027-r0tl01kq	1938	50	E7	E7	NNP
cord-010027-r0tl01kq	1938	51	transcripts	transcript	NNS
cord-010027-r0tl01kq	1938	52	.	.	.
cord-010027-r0tl01kq	1939	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1939	2	assessed	assess	VBD
cord-010027-r0tl01kq	1939	3	the	the	DT
cord-010027-r0tl01kq	1939	4	expression	expression	NN
cord-010027-r0tl01kq	1939	5	pattern	pattern	NN
cord-010027-r0tl01kq	1939	6	of	of	IN
cord-010027-r0tl01kq	1939	7	CK7	CK7	NNP
cord-010027-r0tl01kq	1939	8	protein	protein	NN
cord-010027-r0tl01kq	1939	9	in	in	IN
cord-010027-r0tl01kq	1939	10	tumour	tumour	NN
cord-010027-r0tl01kq	1939	11	specimens	specimen	NNS
cord-010027-r0tl01kq	1939	12	from	from	IN
cord-010027-r0tl01kq	1939	13	patients	patient	NNS
cord-010027-r0tl01kq	1939	14	diagnosed	diagnose	VBN
cord-010027-r0tl01kq	1939	15	with	with	IN
cord-010027-r0tl01kq	1939	16	oropharyngeal	oropharyngeal	JJ
cord-010027-r0tl01kq	1939	17	squamous	squamous	JJ
cord-010027-r0tl01kq	1939	18	cell	cell	NN
cord-010027-r0tl01kq	1939	19	carcinoma	carcinoma	NN
cord-010027-r0tl01kq	1939	20	(	(	-LRB-
cord-010027-r0tl01kq	1939	21	SCC	SCC	NNP
cord-010027-r0tl01kq	1939	22	)	)	-RRB-
cord-010027-r0tl01kq	1939	23	presenting	present	VBG
cord-010027-r0tl01kq	1939	24	at	at	IN
cord-010027-r0tl01kq	1939	25	two	two	CD
cord-010027-r0tl01kq	1939	26	major	major	JJ
cord-010027-r0tl01kq	1939	27	Irish	irish	JJ
cord-010027-r0tl01kq	1939	28	head	head	NN
cord-010027-r0tl01kq	1939	29	and	and	CC
cord-010027-r0tl01kq	1939	30	neck	neck	NN
cord-010027-r0tl01kq	1939	31	centres	centre	NNS
cord-010027-r0tl01kq	1939	32	,	,	,
cord-010027-r0tl01kq	1939	33	within	within	IN
cord-010027-r0tl01kq	1939	34	the	the	DT
cord-010027-r0tl01kq	1939	35	last	last	JJ
cord-010027-r0tl01kq	1939	36	10	10	CD
cord-010027-r0tl01kq	1939	37	years	year	NNS
cord-010027-r0tl01kq	1939	38	.	.	.
cord-010027-r0tl01kq	1940	1	Methods	method	NNS
cord-010027-r0tl01kq	1940	2	:	:	:
cord-010027-r0tl01kq	1941	1	Archived	archived	JJ
cord-010027-r0tl01kq	1941	2	tumour	tumour	NN
cord-010027-r0tl01kq	1941	3	specimens	specimen	NNS
cord-010027-r0tl01kq	1941	4	together	together	RB
cord-010027-r0tl01kq	1941	5	with	with	IN
cord-010027-r0tl01kq	1941	6	epidemiological	epidemiological	JJ
cord-010027-r0tl01kq	1941	7	data	datum	NNS
cord-010027-r0tl01kq	1941	8	were	be	VBD
cord-010027-r0tl01kq	1941	9	collected	collect	VBN
cord-010027-r0tl01kq	1941	10	from	from	IN
cord-010027-r0tl01kq	1941	11	patients	patient	NNS
cord-010027-r0tl01kq	1941	12	presenting	present	VBG
cord-010027-r0tl01kq	1941	13	with	with	IN
cord-010027-r0tl01kq	1941	14	new	new	JJ
cord-010027-r0tl01kq	1941	15	primary	primary	JJ
cord-010027-r0tl01kq	1941	16	oropharyngeal	oropharyngeal	JJ
cord-010027-r0tl01kq	1941	17	SCC	SCC	NNP
cord-010027-r0tl01kq	1941	18	at	at	IN
cord-010027-r0tl01kq	1941	19	two	two	CD
cord-010027-r0tl01kq	1941	20	main	main	JJ
cord-010027-r0tl01kq	1941	21	head	head	NN
cord-010027-r0tl01kq	1941	22	and	and	CC
cord-010027-r0tl01kq	1941	23	neck	neck	NN
cord-010027-r0tl01kq	1941	24	centres	centre	NNS
cord-010027-r0tl01kq	1941	25	in	in	IN
cord-010027-r0tl01kq	1941	26	Ireland	Ireland	NNP
cord-010027-r0tl01kq	1941	27	,	,	,
cord-010027-r0tl01kq	1941	28	within	within	IN
cord-010027-r0tl01kq	1941	29	the	the	DT
cord-010027-r0tl01kq	1941	30	last	last	JJ
cord-010027-r0tl01kq	1941	31	10	10	CD
cord-010027-r0tl01kq	1941	32	years	year	NNS
cord-010027-r0tl01kq	1941	33	.	.	.
cord-010027-r0tl01kq	1942	1	Briefly	briefly	RB
cord-010027-r0tl01kq	1942	2	,	,	,
cord-010027-r0tl01kq	1942	3	DNA	DNA	NNP
cord-010027-r0tl01kq	1942	4	was	be	VBD
cord-010027-r0tl01kq	1942	5	extracted	extract	VBN
cord-010027-r0tl01kq	1942	6	from	from	IN
cord-010027-r0tl01kq	1942	7	tissue	tissue	NN
cord-010027-r0tl01kq	1942	8	blocks	block	NNS
cord-010027-r0tl01kq	1942	9	and	and	CC
cord-010027-r0tl01kq	1942	10	HPV	HPV	NNP
cord-010027-r0tl01kq	1942	11	testing	testing	NN
cord-010027-r0tl01kq	1942	12	carried	carry	VBD
cord-010027-r0tl01kq	1942	13	out	out	RP
cord-010027-r0tl01kq	1942	14	using	use	VBG
cord-010027-r0tl01kq	1942	15	SPF10	SPF10	``
cord-010027-r0tl01kq	1942	16	HPV	HPV	NNP
cord-010027-r0tl01kq	1942	17	PCR	PCR	NNP
cord-010027-r0tl01kq	1942	18	Immunohistochemical	Immunohistochemical	NNP
cord-010027-r0tl01kq	1942	19	staining	stain	VBG
cord-010027-r0tl01kq	1942	20	for	for	IN
cord-010027-r0tl01kq	1942	21	CK7	CK7	NNP
cord-010027-r0tl01kq	1942	22	[	[	-LRB-
cord-010027-r0tl01kq	1942	23	Clone	Clone	NNP
cord-010027-r0tl01kq	1942	24	SP52	SP52	NNP
cord-010027-r0tl01kq	1942	25	,	,	,
cord-010027-r0tl01kq	1942	26	Ventana	Ventana	NNP
cord-010027-r0tl01kq	1942	27	]	]	-RRB-
cord-010027-r0tl01kq	1942	28	was	be	VBD
cord-010027-r0tl01kq	1942	29	performed	perform	VBN
cord-010027-r0tl01kq	1942	30	on	on	IN
cord-010027-r0tl01kq	1942	31	tissue	tissue	NN
cord-010027-r0tl01kq	1942	32	blocks	block	NNS
cord-010027-r0tl01kq	1942	33	following	follow	VBG
cord-010027-r0tl01kq	1942	34	optimisation	optimisation	NN
cord-010027-r0tl01kq	1942	35	on	on	IN
cord-010027-r0tl01kq	1942	36	the	the	DT
cord-010027-r0tl01kq	1942	37	Ventana	Ventana	NNP
cord-010027-r0tl01kq	1942	38	BenchMark	BenchMark	NNP
cord-010027-r0tl01kq	1942	39	Ultra	Ultra	NNP
cord-010027-r0tl01kq	1942	40	Immunostainer	Immunostainer	NNP
cord-010027-r0tl01kq	1942	41	.	.	.
cord-010027-r0tl01kq	1943	1	Slides	slide	NNS
cord-010027-r0tl01kq	1943	2	were	be	VBD
cord-010027-r0tl01kq	1943	3	analysed	analyse	VBN
cord-010027-r0tl01kq	1943	4	by	by	IN
cord-010027-r0tl01kq	1943	5	light	light	JJ
cord-010027-r0tl01kq	1943	6	microscopy	microscopy	NNS
cord-010027-r0tl01kq	1943	7	and	and	CC
cord-010027-r0tl01kq	1943	8	scored	score	VBD
cord-010027-r0tl01kq	1943	9	using	use	VBG
cord-010027-r0tl01kq	1943	10	the	the	DT
cord-010027-r0tl01kq	1943	11	H	h	NN
cord-010027-r0tl01kq	1943	12	scoring	scoring	NN
cord-010027-r0tl01kq	1943	13	system	system	NN
cord-010027-r0tl01kq	1943	14	with	with	IN
cord-010027-r0tl01kq	1943	15	95	95	CD
cord-010027-r0tl01kq	1943	16	%	%	NN
cord-010027-r0tl01kq	1943	17	of	of	IN
cord-010027-r0tl01kq	1943	18	these	these	DT
cord-010027-r0tl01kq	1943	19	identified	identify	VBN
cord-010027-r0tl01kq	1943	20	as	as	IN
cord-010027-r0tl01kq	1943	21	HPV-16	HPV-16	NNP
cord-010027-r0tl01kq	1943	22	subtype	subtype	NN
cord-010027-r0tl01kq	1943	23	.	.	.
cord-010027-r0tl01kq	1944	1	CK7	CK7	NNP
cord-010027-r0tl01kq	1944	2	expression	expression	NN
cord-010027-r0tl01kq	1944	3	was	be	VBD
cord-010027-r0tl01kq	1944	4	observed	observe	VBN
cord-010027-r0tl01kq	1944	5	in	in	IN
cord-010027-r0tl01kq	1944	6	the	the	DT
cord-010027-r0tl01kq	1944	7	tonsillar	tonsillar	JJ
cord-010027-r0tl01kq	1944	8	crypt	crypt	NN
cord-010027-r0tl01kq	1944	9	epithelium	epithelium	NN
cord-010027-r0tl01kq	1944	10	of	of	IN
cord-010027-r0tl01kq	1944	11	both	both	DT
cord-010027-r0tl01kq	1944	12	normal	normal	JJ
cord-010027-r0tl01kq	1944	13	tonsils	tonsil	NNS
cord-010027-r0tl01kq	1944	14	and	and	CC
cord-010027-r0tl01kq	1944	15	tumour	tumour	NN
cord-010027-r0tl01kq	1944	16	specimens	specimen	NNS
cord-010027-r0tl01kq	1944	17	.	.	.
cord-010027-r0tl01kq	1945	1	56	56	CD
cord-010027-r0tl01kq	1945	2	%	%	NN
cord-010027-r0tl01kq	1945	3	of	of	IN
cord-010027-r0tl01kq	1945	4	cases	case	NNS
cord-010027-r0tl01kq	1945	5	were	be	VBD
cord-010027-r0tl01kq	1945	6	positive	positive	JJ
cord-010027-r0tl01kq	1945	7	for	for	IN
cord-010027-r0tl01kq	1945	8	CK7	CK7	NNP
cord-010027-r0tl01kq	1945	9	,	,	,
cord-010027-r0tl01kq	1945	10	with	with	IN
cord-010027-r0tl01kq	1945	11	38	38	CD
cord-010027-r0tl01kq	1945	12	%	%	NN
cord-010027-r0tl01kq	1945	13	of	of	IN
cord-010027-r0tl01kq	1945	14	cases	case	NNS
cord-010027-r0tl01kq	1945	15	demonstrating	demonstrate	VBG
cord-010027-r0tl01kq	1945	16	H	h	NN
cord-010027-r0tl01kq	1945	17	score	score	NN
cord-010027-r0tl01kq	1945	18	of	of	IN
cord-010027-r0tl01kq	1945	19	>	>	XX
cord-010027-r0tl01kq	1945	20	60	60	CD
cord-010027-r0tl01kq	1945	21	.	.	.
cord-010027-r0tl01kq	1946	1	CK7	CK7	NNP
cord-010027-r0tl01kq	1946	2	expression	expression	NN
cord-010027-r0tl01kq	1946	3	in	in	IN
cord-010027-r0tl01kq	1946	4	the	the	DT
cord-010027-r0tl01kq	1946	5	tumour	tumour	NN
cord-010027-r0tl01kq	1946	6	cells	cell	NNS
cord-010027-r0tl01kq	1946	7	was	be	VBD
cord-010027-r0tl01kq	1946	8	significantly	significantly	RB
cord-010027-r0tl01kq	1946	9	linked	link	VBN
cord-010027-r0tl01kq	1946	10	to	to	IN
cord-010027-r0tl01kq	1946	11	HPV	hpv	NN
cord-010027-r0tl01kq	1946	12	status	status	NN
cord-010027-r0tl01kq	1946	13	and	and	CC
cord-010027-r0tl01kq	1946	14	Our	-PRON-	PRP$
cord-010027-r0tl01kq	1946	15	results	result	NNS
cord-010027-r0tl01kq	1946	16	suggest	suggest	VBP
cord-010027-r0tl01kq	1946	17	that	that	IN
cord-010027-r0tl01kq	1946	18	the	the	DT
cord-010027-r0tl01kq	1946	19	expression	expression	NN
cord-010027-r0tl01kq	1946	20	of	of	IN
cord-010027-r0tl01kq	1946	21	CK7	CK7	NNP
cord-010027-r0tl01kq	1946	22	in	in	IN
cord-010027-r0tl01kq	1946	23	normal	normal	JJ
cord-010027-r0tl01kq	1946	24	tonsillar	tonsillar	JJ
cord-010027-r0tl01kq	1946	25	crypt	crypt	NN
cord-010027-r0tl01kq	1946	26	epithelial	epithelial	JJ
cord-010027-r0tl01kq	1946	27	cells	cell	NNS
cord-010027-r0tl01kq	1946	28	provides	provide	VBZ
cord-010027-r0tl01kq	1946	29	a	a	DT
cord-010027-r0tl01kq	1946	30	selective	selective	JJ
cord-010027-r0tl01kq	1946	31	advantage	advantage	NN
cord-010027-r0tl01kq	1946	32	to	to	IN
cord-010027-r0tl01kq	1946	33	HPV	hpv	NN
cord-010027-r0tl01kq	1946	34	-	-	HYPH
cord-010027-r0tl01kq	1946	35	related	relate	VBN
cord-010027-r0tl01kq	1946	36	carcinogenesis	carcinogenesis	NN
cord-010027-r0tl01kq	1946	37	at	at	IN
cord-010027-r0tl01kq	1946	38	this	this	DT
cord-010027-r0tl01kq	1946	39	site	site	NN
cord-010027-r0tl01kq	1946	40	,	,	,
cord-010027-r0tl01kq	1946	41	possible	possible	JJ
cord-010027-r0tl01kq	1946	42	due	due	IN
cord-010027-r0tl01kq	1946	43	to	to	IN
cord-010027-r0tl01kq	1946	44	the	the	DT
cord-010027-r0tl01kq	1946	45	unique	unique	JJ
cord-010027-r0tl01kq	1946	46	propensity	propensity	NN
cord-010027-r0tl01kq	1946	47	of	of	IN
cord-010027-r0tl01kq	1946	48	CK7	CK7	NNP
cord-010027-r0tl01kq	1946	49	to	to	TO
cord-010027-r0tl01kq	1946	50	bind	bind	VB
cord-010027-r0tl01kq	1946	51	and	and	CC
cord-010027-r0tl01kq	1946	52	stabilise	stabilise	VB
cord-010027-r0tl01kq	1946	53	HPV-16	HPV-16	NNP
cord-010027-r0tl01kq	1946	54	E7	E7	NNP
cord-010027-r0tl01kq	1946	55	transcripts	transcript	NNS
cord-010027-r0tl01kq	1946	56	Regan	Regan	NNP
cord-010027-r0tl01kq	1946	57	3	3	CD
cord-010027-r0tl01kq	1946	58	;	;	:
cord-010027-r0tl01kq	1946	59	CM	CM	NNP
cord-010027-r0tl01kq	1946	60	Martin	Martin	NNP
cord-010027-r0tl01kq	1946	61	2	2	CD
cord-010027-r0tl01kq	1946	62	;	;	:
cord-010027-r0tl01kq	1946	63	CV	CV	NNP
cord-010027-r0tl01kq	1946	64	Timon	Timon	NNP
cord-010027-r0tl01kq	1946	65	3	3	CD
cord-010027-r0tl01kq	1946	66	Methods	Methods	NNPS
cord-010027-r0tl01kq	1946	67	:	:	:
cord-010027-r0tl01kq	1946	68	Archived	Archived	NNP
cord-010027-r0tl01kq	1946	69	HPV	hpv	NN
cord-010027-r0tl01kq	1946	70	-	-	HYPH
cord-010027-r0tl01kq	1946	71	positive	positive	JJ
cord-010027-r0tl01kq	1946	72	tumour	tumour	NN
cord-010027-r0tl01kq	1946	73	specimens	specimen	NNS
cord-010027-r0tl01kq	1946	74	and	and	CC
cord-010027-r0tl01kq	1946	75	epidemiological	epidemiological	JJ
cord-010027-r0tl01kq	1946	76	data	datum	NNS
cord-010027-r0tl01kq	1946	77	were	be	VBD
cord-010027-r0tl01kq	1946	78	collected	collect	VBN
cord-010027-r0tl01kq	1946	79	from	from	IN
cord-010027-r0tl01kq	1946	80	patients	patient	NNS
cord-010027-r0tl01kq	1946	81	presenting	present	VBG
cord-010027-r0tl01kq	1946	82	with	with	IN
cord-010027-r0tl01kq	1946	83	new	new	JJ
cord-010027-r0tl01kq	1946	84	primary	primary	JJ
cord-010027-r0tl01kq	1946	85	oropharyngeal	oropharyngeal	JJ
cord-010027-r0tl01kq	1946	86	SCC	SCC	NNP
cord-010027-r0tl01kq	1946	87	at	at	IN
cord-010027-r0tl01kq	1946	88	two	two	CD
cord-010027-r0tl01kq	1946	89	head	head	NN
cord-010027-r0tl01kq	1946	90	and	and	CC
cord-010027-r0tl01kq	1946	91	neck	neck	NN
cord-010027-r0tl01kq	1946	92	centres	centre	NNS
cord-010027-r0tl01kq	1946	93	in	in	IN
cord-010027-r0tl01kq	1946	94	Ireland	Ireland	NNP
cord-010027-r0tl01kq	1946	95	over	over	IN
cord-010027-r0tl01kq	1946	96	a	a	DT
cord-010027-r0tl01kq	1946	97	one	one	CD
cord-010027-r0tl01kq	1946	98	year	year	NN
cord-010027-r0tl01kq	1946	99	period	period	NN
cord-010027-r0tl01kq	1946	100	.	.	.
cord-010027-r0tl01kq	1947	1	Briefly	briefly	RB
cord-010027-r0tl01kq	1947	2	,	,	,
cord-010027-r0tl01kq	1947	3	DNA	DNA	NNP
cord-010027-r0tl01kq	1947	4	was	be	VBD
cord-010027-r0tl01kq	1947	5	extracted	extract	VBN
cord-010027-r0tl01kq	1947	6	from	from	IN
cord-010027-r0tl01kq	1947	7	tissue	tissue	NN
cord-010027-r0tl01kq	1947	8	blocks	block	NNS
cord-010027-r0tl01kq	1947	9	and	and	CC
cord-010027-r0tl01kq	1947	10	HPV	HPV	NNP
cord-010027-r0tl01kq	1947	11	testing	testing	NN
cord-010027-r0tl01kq	1947	12	carried	carry	VBD
cord-010027-r0tl01kq	1947	13	out	out	RP
cord-010027-r0tl01kq	1947	14	using	use	VBG
cord-010027-r0tl01kq	1947	15	SPF10	SPF10	``
cord-010027-r0tl01kq	1947	16	HPV	HPV	NNP
cord-010027-r0tl01kq	1947	17	PCR	PCR	NNP
cord-010027-r0tl01kq	1947	18	.	.	.
cord-010027-r0tl01kq	1948	1	The	the	DT
cord-010027-r0tl01kq	1948	2	INNO	INNO	NNP
cord-010027-r0tl01kq	1948	3	-	-	JJ
cord-010027-r0tl01kq	1948	4	LiPA	LiPA	NNP
cord-010027-r0tl01kq	1948	5	HPV	HPV	NNP
cord-010027-r0tl01kq	1948	6	Genotyping	Genotyping	NNP
cord-010027-r0tl01kq	1948	7	Extra	Extra	NNP
cord-010027-r0tl01kq	1948	8	test	test	NN
cord-010027-r0tl01kq	1948	9	[	[	-LRB-
cord-010027-r0tl01kq	1948	10	Fujirebio	Fujirebio	NNP
cord-010027-r0tl01kq	1948	11	]	]	-RRB-
cord-010027-r0tl01kq	1948	12	was	be	VBD
cord-010027-r0tl01kq	1948	13	used	use	VBN
cord-010027-r0tl01kq	1948	14	to	to	TO
cord-010027-r0tl01kq	1948	15	determine	determine	VB
cord-010027-r0tl01kq	1948	16	genotype	genotype	NN
cord-010027-r0tl01kq	1948	17	.	.	.
cord-010027-r0tl01kq	1949	1	Immunohistochemical	immunohistochemical	JJ
cord-010027-r0tl01kq	1949	2	staining	stain	VBG
cord-010027-r0tl01kq	1949	3	for	for	IN
cord-010027-r0tl01kq	1949	4	CK7	CK7	NNP
cord-010027-r0tl01kq	1949	5	,	,	,
cord-010027-r0tl01kq	1949	6	GDA	GDA	NNP
cord-010027-r0tl01kq	1949	7	,	,	,
cord-010027-r0tl01kq	1949	8	MMP-7	MMP-7	NNP
cord-010027-r0tl01kq	1949	9	,	,	,
cord-010027-r0tl01kq	1949	10	AGR-2	AGR-2	NNP
cord-010027-r0tl01kq	1949	11	,	,	,
cord-010027-r0tl01kq	1949	12	PD-1	PD-1	NNP
cord-010027-r0tl01kq	1949	13	and	and	CC
cord-010027-r0tl01kq	1949	14	PD	PD	NNP
cord-010027-r0tl01kq	1949	15	-	-	HYPH
cord-010027-r0tl01kq	1949	16	L1	L1	NNP
cord-010027-r0tl01kq	1949	17	was	be	VBD
cord-010027-r0tl01kq	1949	18	performed	perform	VBN
cord-010027-r0tl01kq	1949	19	following	follow	VBG
cord-010027-r0tl01kq	1949	20	optimisation	optimisation	NN
cord-010027-r0tl01kq	1949	21	.	.	.
cord-010027-r0tl01kq	1950	1	Slides	slide	NNS
cord-010027-r0tl01kq	1950	2	were	be	VBD
cord-010027-r0tl01kq	1950	3	analysed	analyse	VBN
cord-010027-r0tl01kq	1950	4	by	by	IN
cord-010027-r0tl01kq	1950	5	light	light	JJ
cord-010027-r0tl01kq	1950	6	microscopy	microscopy	NNS
cord-010027-r0tl01kq	1950	7	and	and	CC
cord-010027-r0tl01kq	1950	8	scored	score	VBD
cord-010027-r0tl01kq	1950	9	using	use	VBG
cord-010027-r0tl01kq	1950	10	the	the	DT
cord-010027-r0tl01kq	1950	11	H	h	NN
cord-010027-r0tl01kq	1950	12	scoring	scoring	NN
cord-010027-r0tl01kq	1950	13	system	system	NN
cord-010027-r0tl01kq	1950	14	(	(	-LRB-
cord-010027-r0tl01kq	1950	15	junctional	junctional	JJ
cord-010027-r0tl01kq	1950	16	biomarkers	biomarker	NNS
cord-010027-r0tl01kq	1950	17	)	)	-RRB-
cord-010027-r0tl01kq	1951	1	Frozen	Frozen	NNP
cord-010027-r0tl01kq	1951	2	Section	Section	NNP
cord-010027-r0tl01kq	1951	3	Reporting	Reporting	NNP
cord-010027-r0tl01kq	1951	4	of	of	IN
cord-010027-r0tl01kq	1951	5	Necrotising	Necrotising	NNP
cord-010027-r0tl01kq	1951	6	Granuloma	Granuloma	NNP
cord-010027-r0tl01kq	1951	7	of	of	IN
cord-010027-r0tl01kq	1951	8	the	the	DT
cord-010027-r0tl01kq	1951	9	Liver	liver	NN
cord-010027-r0tl01kq	1952	1	Following	follow	VBG
cord-010027-r0tl01kq	1952	2	Percutaneous	Percutaneous	NNP
cord-010027-r0tl01kq	1952	3	Instrumentation	Instrumentation	NNP
cord-010027-r0tl01kq	1952	4	of	of	IN
cord-010027-r0tl01kq	1952	5	The	the	DT
cord-010027-r0tl01kq	1952	6	Biliary	Biliary	NNP
cord-010027-r0tl01kq	1952	7	Tree	Tree	NNP
cord-010027-r0tl01kq	1952	8	:	:	:
cord-010027-r0tl01kq	1953	1	A	a	DT
cord-010027-r0tl01kq	1953	2	Case	Case	NNP
cord-010027-r0tl01kq	1953	3	Series	Series	NNP
cord-010027-r0tl01kq	1953	4	EH	EH	NNP
cord-010027-r0tl01kq	1953	5	Hadjimichael	Hadjimichael	NNP
cord-010027-r0tl01kq	1953	6	;	;	:
cord-010027-r0tl01kq	1953	7	P	p	NN
cord-010027-r0tl01kq	1953	8	DF	DF	NNP
cord-010027-r0tl01kq	1953	9	Fielding	Fielding	NNP
cord-010027-r0tl01kq	1953	10	;	;	:
cord-010027-r0tl01kq	1953	11	MI	MI	NNP
cord-010027-r0tl01kq	1953	12	Ilyas	Ilyas	NNP
cord-010027-r0tl01kq	1953	13	;	;	:
cord-010027-r0tl01kq	1953	14	AZ	AZ	NNP
cord-010027-r0tl01kq	1953	15	Zaitoun	Zaitoun	NNP
cord-010027-r0tl01kq	1953	16	;	;	:
cord-010027-r0tl01kq	1953	17	DL	DL	NNP
cord-010027-r0tl01kq	1953	18	Lobo	Lobo	NNP
cord-010027-r0tl01kq	1953	19	;	;	:
cord-010027-r0tl01kq	1953	20	PK	PK	NNP
cord-010027-r0tl01kq	1953	21	Kaye	Kaye	NNP
cord-010027-r0tl01kq	1953	22	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	1953	23	University	University	NNP
cord-010027-r0tl01kq	1953	24	Hospital	Hospital	NNP
cord-010027-r0tl01kq	1953	25	,	,	,
cord-010027-r0tl01kq	1953	26	Nottingham	Nottingham	NNP
cord-010027-r0tl01kq	1953	27	,	,	,
cord-010027-r0tl01kq	1953	28	UK	UK	NNP
cord-010027-r0tl01kq	1953	29	Percutaneous	Percutaneous	NNP
cord-010027-r0tl01kq	1953	30	transhepatic	transhepatic	JJ
cord-010027-r0tl01kq	1953	31	cholangiography	cholangiography	NN
cord-010027-r0tl01kq	1953	32	(	(	-LRB-
cord-010027-r0tl01kq	1953	33	PTC	PTC	NNP
cord-010027-r0tl01kq	1953	34	)	)	-RRB-
cord-010027-r0tl01kq	1953	35	is	be	VBZ
cord-010027-r0tl01kq	1953	36	an	an	DT
cord-010027-r0tl01kq	1953	37	interventional	interventional	JJ
cord-010027-r0tl01kq	1953	38	radiological	radiological	JJ
cord-010027-r0tl01kq	1953	39	technique	technique	NN
cord-010027-r0tl01kq	1953	40	for	for	IN
cord-010027-r0tl01kq	1953	41	both	both	CC
cord-010027-r0tl01kq	1953	42	diagnostic	diagnostic	JJ
cord-010027-r0tl01kq	1953	43	imaging	imaging	NN
cord-010027-r0tl01kq	1953	44	and	and	CC
cord-010027-r0tl01kq	1953	45	therapeutic	therapeutic	JJ
cord-010027-r0tl01kq	1953	46	decompression	decompression	NN
cord-010027-r0tl01kq	1953	47	of	of	IN
cord-010027-r0tl01kq	1953	48	the	the	DT
cord-010027-r0tl01kq	1953	49	proximal	proximal	JJ
cord-010027-r0tl01kq	1953	50	biliary	biliary	JJ
cord-010027-r0tl01kq	1953	51	tract	tract	NN
cord-010027-r0tl01kq	1953	52	in	in	IN
cord-010027-r0tl01kq	1953	53	malignant	malignant	JJ
cord-010027-r0tl01kq	1953	54	distal	distal	JJ
cord-010027-r0tl01kq	1953	55	obstruction	obstruction	NN
cord-010027-r0tl01kq	1953	56	when	when	WRB
cord-010027-r0tl01kq	1953	57	retrograde	retrograde	JJ
cord-010027-r0tl01kq	1953	58	techniques	technique	NNS
cord-010027-r0tl01kq	1953	59	fail	fail	VBP
cord-010027-r0tl01kq	1953	60	.	.	.
cord-010027-r0tl01kq	1954	1	Recognised	recognise	VBN
cord-010027-r0tl01kq	1954	2	complications	complication	NNS
cord-010027-r0tl01kq	1954	3	of	of	IN
cord-010027-r0tl01kq	1954	4	PTC	PTC	NNP
cord-010027-r0tl01kq	1954	5	include	include	VBP
cord-010027-r0tl01kq	1954	6	sepsis	sepsis	NN
cord-010027-r0tl01kq	1954	7	,	,	,
cord-010027-r0tl01kq	1954	8	haemorrhage	haemorrhage	NN
cord-010027-r0tl01kq	1954	9	and	and	CC
cord-010027-r0tl01kq	1954	10	pneumothorax	pneumothorax	NN
cord-010027-r0tl01kq	1954	11	.	.	.
cord-010027-r0tl01kq	1955	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1955	2	describe	describe	VBP
cord-010027-r0tl01kq	1955	3	four	four	CD
cord-010027-r0tl01kq	1955	4	cases	case	NNS
cord-010027-r0tl01kq	1955	5	where	where	WRB
cord-010027-r0tl01kq	1955	6	necrotising	necrotise	VBG
cord-010027-r0tl01kq	1955	7	granuloma	granuloma	NN
cord-010027-r0tl01kq	1955	8	,	,	,
cord-010027-r0tl01kq	1955	9	apparently	apparently	RB
cord-010027-r0tl01kq	1955	10	secondary	secondary	JJ
cord-010027-r0tl01kq	1955	11	to	to	IN
cord-010027-r0tl01kq	1955	12	previous	previous	JJ
cord-010027-r0tl01kq	1955	13	PTC	PTC	NNP
cord-010027-r0tl01kq	1955	14	,	,	,
cord-010027-r0tl01kq	1955	15	has	have	VBZ
cord-010027-r0tl01kq	1955	16	resulted	result	VBN
cord-010027-r0tl01kq	1955	17	in	in	IN
cord-010027-r0tl01kq	1955	18	frozen	frozen	JJ
cord-010027-r0tl01kq	1955	19	section	section	NN
cord-010027-r0tl01kq	1955	20	examination	examination	NN
cord-010027-r0tl01kq	1955	21	at	at	IN
cord-010027-r0tl01kq	1955	22	the	the	DT
cord-010027-r0tl01kq	1955	23	time	time	NN
cord-010027-r0tl01kq	1955	24	of	of	IN
cord-010027-r0tl01kq	1955	25	subsequent	subsequent	JJ
cord-010027-r0tl01kq	1955	26	planned	plan	VBN
cord-010027-r0tl01kq	1955	27	cancer	cancer	NN
cord-010027-r0tl01kq	1955	28	resection	resection	NN
cord-010027-r0tl01kq	1955	29	,	,	,
cord-010027-r0tl01kq	1955	30	to	to	TO
cord-010027-r0tl01kq	1955	31	exclude	exclude	VB
cord-010027-r0tl01kq	1955	32	tumour	tumour	NN
cord-010027-r0tl01kq	1955	33	metastasis	metastasis	NN
cord-010027-r0tl01kq	1955	34	.	.	.
cord-010027-r0tl01kq	1956	1	Four	four	CD
cord-010027-r0tl01kq	1956	2	cases	case	NNS
cord-010027-r0tl01kq	1956	3	of	of	IN
cord-010027-r0tl01kq	1956	4	necrotising	necrotise	VBG
cord-010027-r0tl01kq	1956	5	granuloma	granuloma	NN
cord-010027-r0tl01kq	1956	6	in	in	IN
cord-010027-r0tl01kq	1956	7	the	the	DT
cord-010027-r0tl01kq	1956	8	liver	liver	NN
cord-010027-r0tl01kq	1956	9	have	have	VBP
cord-010027-r0tl01kq	1956	10	been	be	VBN
cord-010027-r0tl01kq	1956	11	identified	identify	VBN
cord-010027-r0tl01kq	1956	12	between	between	IN
cord-010027-r0tl01kq	1956	13	January	January	NNP
cord-010027-r0tl01kq	1956	14	2013	2013	CD
cord-010027-r0tl01kq	1956	15	and	and	CC
cord-010027-r0tl01kq	1956	16	February	February	NNP
cord-010027-r0tl01kq	1956	17	2015	2015	CD
cord-010027-r0tl01kq	1956	18	.	.	.
cord-010027-r0tl01kq	1957	1	All	all	DT
cord-010027-r0tl01kq	1957	2	cases	case	NNS
cord-010027-r0tl01kq	1957	3	were	be	VBD
cord-010027-r0tl01kq	1957	4	planned	plan	VBN
cord-010027-r0tl01kq	1957	5	Whipple	Whipple	NNP
cord-010027-r0tl01kq	1957	6	's	's	POS
cord-010027-r0tl01kq	1957	7	procedures	procedure	NNS
cord-010027-r0tl01kq	1957	8	for	for	IN
cord-010027-r0tl01kq	1957	9	pancreatic	pancreatic	JJ
cord-010027-r0tl01kq	1957	10	cancer	cancer	NN
cord-010027-r0tl01kq	1957	11	where	where	WRB
cord-010027-r0tl01kq	1957	12	initial	initial	JJ
cord-010027-r0tl01kq	1957	13	intraoperative	intraoperative	JJ
cord-010027-r0tl01kq	1957	14	evaluation	evaluation	NN
cord-010027-r0tl01kq	1957	15	revealed	reveal	VBD
cord-010027-r0tl01kq	1957	16	solitary	solitary	JJ
cord-010027-r0tl01kq	1957	17	subcapsular	subcapsular	NNP
cord-010027-r0tl01kq	1957	18	liver	liver	NN
cord-010027-r0tl01kq	1957	19	lesions	lesion	NNS
cord-010027-r0tl01kq	1957	20	.	.	.
cord-010027-r0tl01kq	1958	1	Biopsy	biopsy	JJ
cord-010027-r0tl01kq	1958	2	and	and	CC
cord-010027-r0tl01kq	1958	3	intraoperative	intraoperative	JJ
cord-010027-r0tl01kq	1958	4	frozen	frozen	JJ
cord-010027-r0tl01kq	1958	5	section	section	NN
cord-010027-r0tl01kq	1958	6	examination	examination	NN
cord-010027-r0tl01kq	1958	7	were	be	VBD
cord-010027-r0tl01kq	1958	8	performed	perform	VBN
cord-010027-r0tl01kq	1958	9	to	to	TO
cord-010027-r0tl01kq	1958	10	exclude	exclude	VB
cord-010027-r0tl01kq	1958	11	metastatic	metastatic	JJ
cord-010027-r0tl01kq	1958	12	disease	disease	NN
cord-010027-r0tl01kq	1958	13	.	.	.
cord-010027-r0tl01kq	1959	1	All	all	DT
cord-010027-r0tl01kq	1959	2	frozen	frozen	JJ
cord-010027-r0tl01kq	1959	3	sections	section	NNS
cord-010027-r0tl01kq	1959	4	except	except	IN
cord-010027-r0tl01kq	1959	5	one	one	CD
cord-010027-r0tl01kq	1959	6	were	be	VBD
cord-010027-r0tl01kq	1959	7	reported	report	VBN
cord-010027-r0tl01kq	1959	8	as	as	IN
cord-010027-r0tl01kq	1959	9	showing	show	VBG
cord-010027-r0tl01kq	1959	10	benign	benign	JJ
cord-010027-r0tl01kq	1959	11	necrotizing	necrotize	VBG
cord-010027-r0tl01kq	1959	12	granuloma	granuloma	NN
cord-010027-r0tl01kq	1959	13	formation	formation	NN
cord-010027-r0tl01kq	1959	14	.	.	.
cord-010027-r0tl01kq	1960	1	The	the	DT
cord-010027-r0tl01kq	1960	2	first	first	JJ
cord-010027-r0tl01kq	1960	3	case	case	NN
cord-010027-r0tl01kq	1960	4	was	be	VBD
cord-010027-r0tl01kq	1960	5	initially	initially	RB
cord-010027-r0tl01kq	1960	6	reported	report	VBN
cord-010027-r0tl01kq	1960	7	as	as	IN
cord-010027-r0tl01kq	1960	8	malignant	malignant	JJ
cord-010027-r0tl01kq	1960	9	and	and	CC
cord-010027-r0tl01kq	1960	10	the	the	DT
cord-010027-r0tl01kq	1960	11	operation	operation	NN
cord-010027-r0tl01kq	1960	12	was	be	VBD
cord-010027-r0tl01kq	1960	13	abandoned	abandon	VBN
cord-010027-r0tl01kq	1960	14	.	.	.
cord-010027-r0tl01kq	1961	1	A	a	DT
cord-010027-r0tl01kq	1961	2	benign	benign	JJ
cord-010027-r0tl01kq	1961	3	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1961	4	was	be	VBD
cord-010027-r0tl01kq	1961	5	confirmed	confirm	VBN
cord-010027-r0tl01kq	1961	6	on	on	IN
cord-010027-r0tl01kq	1961	7	paraffin	paraffin	NN
cord-010027-r0tl01kq	1961	8	sections	section	NNS
cord-010027-r0tl01kq	1961	9	in	in	IN
cord-010027-r0tl01kq	1961	10	all	all	DT
cord-010027-r0tl01kq	1961	11	four	four	CD
cord-010027-r0tl01kq	1961	12	cases	case	NNS
cord-010027-r0tl01kq	1961	13	with	with	IN
cord-010027-r0tl01kq	1961	14	the	the	DT
cord-010027-r0tl01kq	1961	15	first	first	JJ
cord-010027-r0tl01kq	1961	16	patient	patient	NN
cord-010027-r0tl01kq	1961	17	undergoing	undergo	VBG
cord-010027-r0tl01kq	1961	18	successful	successful	JJ
cord-010027-r0tl01kq	1961	19	surgical	surgical	JJ
cord-010027-r0tl01kq	1961	20	resection	resection	NN
cord-010027-r0tl01kq	1961	21	at	at	IN
cord-010027-r0tl01kq	1961	22	a	a	DT
cord-010027-r0tl01kq	1961	23	later	later	JJ
cord-010027-r0tl01kq	1961	24	date	date	NN
cord-010027-r0tl01kq	1961	25	.	.	.
cord-010027-r0tl01kq	1962	1	To	to	IN
cord-010027-r0tl01kq	1962	2	the	the	DT
cord-010027-r0tl01kq	1962	3	best	good	JJS
cord-010027-r0tl01kq	1962	4	of	of	IN
cord-010027-r0tl01kq	1962	5	our	-PRON-	PRP$
cord-010027-r0tl01kq	1962	6	knowledge	knowledge	NN
cord-010027-r0tl01kq	1962	7	these	these	DT
cord-010027-r0tl01kq	1962	8	are	be	VBP
cord-010027-r0tl01kq	1962	9	the	the	DT
cord-010027-r0tl01kq	1962	10	first	first	JJ
cord-010027-r0tl01kq	1962	11	reported	report	VBN
cord-010027-r0tl01kq	1962	12	cases	case	NNS
cord-010027-r0tl01kq	1962	13	of	of	IN
cord-010027-r0tl01kq	1962	14	necrotising	necrotise	VBG
cord-010027-r0tl01kq	1962	15	granuloma	granuloma	NN
cord-010027-r0tl01kq	1962	16	in	in	IN
cord-010027-r0tl01kq	1962	17	the	the	DT
cord-010027-r0tl01kq	1962	18	liver	liver	NN
cord-010027-r0tl01kq	1962	19	secondary	secondary	JJ
cord-010027-r0tl01kq	1962	20	to	to	IN
cord-010027-r0tl01kq	1962	21	prior	prior	JJ
cord-010027-r0tl01kq	1962	22	instrumentation	instrumentation	NN
cord-010027-r0tl01kq	1962	23	of	of	IN
cord-010027-r0tl01kq	1962	24	the	the	DT
cord-010027-r0tl01kq	1962	25	liver	liver	NN
cord-010027-r0tl01kq	1962	26	and	and	CC
cord-010027-r0tl01kq	1962	27	leading	lead	VBG
cord-010027-r0tl01kq	1962	28	to	to	IN
cord-010027-r0tl01kq	1962	29	intraoperative	intraoperative	JJ
cord-010027-r0tl01kq	1962	30	histological	histological	JJ
cord-010027-r0tl01kq	1962	31	assessment	assessment	NN
cord-010027-r0tl01kq	1962	32	.	.	.
cord-010027-r0tl01kq	1963	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1963	2	highlight	highlight	VBP
cord-010027-r0tl01kq	1963	3	this	this	DT
cord-010027-r0tl01kq	1963	4	as	as	IN
cord-010027-r0tl01kq	1963	5	a	a	DT
cord-010027-r0tl01kq	1963	6	potential	potential	JJ
cord-010027-r0tl01kq	1963	7	pitfall	pitfall	NN
cord-010027-r0tl01kq	1963	8	in	in	IN
cord-010027-r0tl01kq	1963	9	frozen	frozen	JJ
cord-010027-r0tl01kq	1963	10	section	section	NN
cord-010027-r0tl01kq	1963	11	interpretation	interpretation	NN
cord-010027-r0tl01kq	1963	12	undertaken	undertake	VBN
cord-010027-r0tl01kq	1963	13	ahead	ahead	RB
cord-010027-r0tl01kq	1963	14	of	of	IN
cord-010027-r0tl01kq	1963	15	planned	plan	VBN
cord-010027-r0tl01kq	1963	16	potentially	potentially	RB
cord-010027-r0tl01kq	1963	17	curative	curative	JJ
cord-010027-r0tl01kq	1963	18	surgery	surgery	NN
cord-010027-r0tl01kq	1963	19	which	which	WDT
cord-010027-r0tl01kq	1963	20	can	can	MD
cord-010027-r0tl01kq	1963	21	lead	lead	VB
cord-010027-r0tl01kq	1963	22	to	to	IN
cord-010027-r0tl01kq	1963	23	overstaging	overstaging	NN
cord-010027-r0tl01kq	1963	24	of	of	IN
cord-010027-r0tl01kq	1963	25	otherwise	otherwise	RB
cord-010027-r0tl01kq	1963	26	resectable	resectable	JJ
cord-010027-r0tl01kq	1963	27	disease	disease	NN
cord-010027-r0tl01kq	1963	28	or	or	CC
cord-010027-r0tl01kq	1963	29	to	to	IN
cord-010027-r0tl01kq	1963	30	the	the	DT
cord-010027-r0tl01kq	1963	31	interpretation	interpretation	NN
cord-010027-r0tl01kq	1963	32	of	of	IN
cord-010027-r0tl01kq	1963	33	a	a	DT
cord-010027-r0tl01kq	1963	34	potential	potential	JJ
cord-010027-r0tl01kq	1963	35	diagnosis	diagnosis	NN
cord-010027-r0tl01kq	1963	36	of	of	IN
cord-010027-r0tl01kq	1963	37	tuberculosis	tuberculosis	NN
cord-010027-r0tl01kq	1963	38	.	.	.
cord-010027-r0tl01kq	1964	1	These	these	DT
cord-010027-r0tl01kq	1964	2	risks	risk	NNS
cord-010027-r0tl01kq	1964	3	can	can	MD
cord-010027-r0tl01kq	1964	4	be	be	VB
cord-010027-r0tl01kq	1964	5	reduced	reduce	VBN
cord-010027-r0tl01kq	1964	6	with	with	IN
cord-010027-r0tl01kq	1964	7	greater	great	JJR
cord-010027-r0tl01kq	1964	8	surgical	surgical	JJ
cord-010027-r0tl01kq	1964	9	and	and	CC
cord-010027-r0tl01kq	1964	10	pathological	pathological	JJ
cord-010027-r0tl01kq	1964	11	awareness	awareness	NN
cord-010027-r0tl01kq	1964	12	of	of	IN
cord-010027-r0tl01kq	1964	13	this	this	DT
cord-010027-r0tl01kq	1964	14	entity	entity	NN
cord-010027-r0tl01kq	1964	15	.	.	.
cord-010027-r0tl01kq	1965	1	Inclusion	inclusion	NN
cord-010027-r0tl01kq	1965	2	body	body	NN
cord-010027-r0tl01kq	1965	3	fibromatosis	fibromatosis	NN
cord-010027-r0tl01kq	1965	4	,	,	,
cord-010027-r0tl01kq	1965	5	also	also	RB
cord-010027-r0tl01kq	1965	6	known	know	VBN
cord-010027-r0tl01kq	1965	7	as	as	IN
cord-010027-r0tl01kq	1965	8	infantile	infantile	JJ
cord-010027-r0tl01kq	1965	9	digital	digital	JJ
cord-010027-r0tl01kq	1965	10	fibroma	fibroma	NN
cord-010027-r0tl01kq	1965	11	,	,	,
cord-010027-r0tl01kq	1965	12	is	be	VBZ
cord-010027-r0tl01kq	1965	13	a	a	DT
cord-010027-r0tl01kq	1965	14	benign	benign	JJ
cord-010027-r0tl01kq	1965	15	,	,	,
cord-010027-r0tl01kq	1965	16	predominantly	predominantly	RB
cord-010027-r0tl01kq	1965	17	myofibroblastic	myofibroblastic	JJ
cord-010027-r0tl01kq	1965	18	tumour	tumour	NN
cord-010027-r0tl01kq	1965	19	primarily	primarily	RB
cord-010027-r0tl01kq	1965	20	found	find	VBD
cord-010027-r0tl01kq	1965	21	on	on	IN
cord-010027-r0tl01kq	1965	22	the	the	DT
cord-010027-r0tl01kq	1965	23	digits	digit	NNS
cord-010027-r0tl01kq	1965	24	of	of	IN
cord-010027-r0tl01kq	1965	25	infants	infant	NNS
cord-010027-r0tl01kq	1965	26	.	.	.
cord-010027-r0tl01kq	1966	1	Clinically	clinically	RB
cord-010027-r0tl01kq	1966	2	,	,	,
cord-010027-r0tl01kq	1966	3	these	these	DT
cord-010027-r0tl01kq	1966	4	lesions	lesion	NNS
cord-010027-r0tl01kq	1966	5	present	present	JJ
cord-010027-r0tl01kq	1966	6	as	as	IN
cord-010027-r0tl01kq	1966	7	asymptomatic	asymptomatic	JJ
cord-010027-r0tl01kq	1966	8	cutaneous	cutaneous	JJ
cord-010027-r0tl01kq	1966	9	nodules	nodule	NNS
cord-010027-r0tl01kq	1966	10	,	,	,
cord-010027-r0tl01kq	1966	11	rarely	rarely	RB
cord-010027-r0tl01kq	1966	12	larger	large	JJR
cord-010027-r0tl01kq	1966	13	than	than	IN
cord-010027-r0tl01kq	1966	14	2	2	CD
cord-010027-r0tl01kq	1966	15	cm	cm	NNS
cord-010027-r0tl01kq	1966	16	in	in	IN
cord-010027-r0tl01kq	1966	17	size	size	NN
cord-010027-r0tl01kq	1966	18	,	,	,
cord-010027-r0tl01kq	1966	19	classically	classically	RB
cord-010027-r0tl01kq	1966	20	on	on	IN
cord-010027-r0tl01kq	1966	21	the	the	DT
cord-010027-r0tl01kq	1966	22	dorsal	dorsal	JJ
cord-010027-r0tl01kq	1966	23	or	or	CC
cord-010027-r0tl01kq	1966	24	dorsolateral	dorsolateral	JJ
cord-010027-r0tl01kq	1966	25	aspect	aspect	NN
cord-010027-r0tl01kq	1966	26	of	of	IN
cord-010027-r0tl01kq	1966	27	the	the	DT
cord-010027-r0tl01kq	1966	28	second	second	JJ
cord-010027-r0tl01kq	1966	29	,	,	,
cord-010027-r0tl01kq	1966	30	third	third	JJ
cord-010027-r0tl01kq	1966	31	and	and	CC
cord-010027-r0tl01kq	1966	32	forth	forth	RB
cord-010027-r0tl01kq	1966	33	digits	digit	NNS
cord-010027-r0tl01kq	1966	34	.	.	.
cord-010027-r0tl01kq	1967	1	They	-PRON-	PRP
cord-010027-r0tl01kq	1967	2	have	have	VBP
cord-010027-r0tl01kq	1967	3	a	a	DT
cord-010027-r0tl01kq	1967	4	high	high	JJ
cord-010027-r0tl01kq	1967	5	recurrence	recurrence	NN
cord-010027-r0tl01kq	1967	6	rate	rate	NN
cord-010027-r0tl01kq	1967	7	,	,	,
cord-010027-r0tl01kq	1967	8	reported	report	VBD
cord-010027-r0tl01kq	1967	9	as	as	IN
cord-010027-r0tl01kq	1967	10	between	between	IN
cord-010027-r0tl01kq	1967	11	61	61	CD
cord-010027-r0tl01kq	1967	12	and	and	CC
cord-010027-r0tl01kq	1967	13	75	75	CD
cord-010027-r0tl01kq	1967	14	%	%	NN
cord-010027-r0tl01kq	1967	15	,	,	,
cord-010027-r0tl01kq	1967	16	although	although	IN
cord-010027-r0tl01kq	1967	17	this	this	DT
cord-010027-r0tl01kq	1967	18	can	can	MD
cord-010027-r0tl01kq	1967	19	be	be	VB
cord-010027-r0tl01kq	1967	20	reduced	reduce	VBN
cord-010027-r0tl01kq	1967	21	by	by	IN
cord-010027-r0tl01kq	1967	22	undertaking	undertake	VBG
cord-010027-r0tl01kq	1967	23	complete	complete	JJ
cord-010027-r0tl01kq	1967	24	wide	wide	JJ
cord-010027-r0tl01kq	1967	25	local	local	JJ
cord-010027-r0tl01kq	1967	26	excision	excision	NN
cord-010027-r0tl01kq	1967	27	.	.	.
cord-010027-r0tl01kq	1968	1	We	-PRON-	PRP
cord-010027-r0tl01kq	1968	2	report	report	VBP
cord-010027-r0tl01kq	1968	3	a	a	DT
cord-010027-r0tl01kq	1968	4	case	case	NN
cord-010027-r0tl01kq	1968	5	of	of	IN
cord-010027-r0tl01kq	1968	6	inclusion	inclusion	NN
cord-010027-r0tl01kq	1968	7	body	body	NN
cord-010027-r0tl01kq	1968	8	fibromatosis	fibromatosis	NN
cord-010027-r0tl01kq	1968	9	in	in	IN
cord-010027-r0tl01kq	1968	10	an	an	DT
cord-010027-r0tl01kq	1968	11	11	11	CD
cord-010027-r0tl01kq	1968	12	month	month	NN
cord-010027-r0tl01kq	1968	13	-	-	HYPH
cord-010027-r0tl01kq	1968	14	old	old	JJ
cord-010027-r0tl01kq	1968	15	boy	boy	NN
cord-010027-r0tl01kq	1968	16	,	,	,
cord-010027-r0tl01kq	1968	17	presenting	present	VBG
cord-010027-r0tl01kq	1968	18	with	with	IN
cord-010027-r0tl01kq	1968	19	an	an	DT
cord-010027-r0tl01kq	1968	20	enlarging	enlarge	VBG
cord-010027-r0tl01kq	1968	21	,	,	,
cord-010027-r0tl01kq	1968	22	firm	firm	JJ
cord-010027-r0tl01kq	1968	23	lesion	lesion	NN
cord-010027-r0tl01kq	1968	24	on	on	IN
cord-010027-r0tl01kq	1968	25	his	-PRON-	PRP$
cord-010027-r0tl01kq	1968	26	left	left	JJ
cord-010027-r0tl01kq	1968	27	second	second	JJ
cord-010027-r0tl01kq	1968	28	toe	toe	NN
cord-010027-r0tl01kq	1968	29	.	.	.
cord-010027-r0tl01kq	1969	1	Following	follow	VBG
cord-010027-r0tl01kq	1969	2	surgical	surgical	JJ
cord-010027-r0tl01kq	1969	3	excision	excision	NN
cord-010027-r0tl01kq	1969	4	,	,	,
cord-010027-r0tl01kq	1969	5	the	the	DT
cord-010027-r0tl01kq	1969	6	lesion	lesion	NN
cord-010027-r0tl01kq	1969	7	showed	show	VBD
cord-010027-r0tl01kq	1969	8	classical	classical	JJ
cord-010027-r0tl01kq	1969	9	histological	histological	JJ
cord-010027-r0tl01kq	1969	10	features	feature	NNS
cord-010027-r0tl01kq	1969	11	of	of	IN
cord-010027-r0tl01kq	1969	12	inclusion	inclusion	NN
cord-010027-r0tl01kq	1969	13	body	body	NN
cord-010027-r0tl01kq	1969	14	fibromatosis	fibromatosis	NN
cord-010027-r0tl01kq	1969	15	-spindle	-spindle	HYPH
cord-010027-r0tl01kq	1969	16	cells	cell	NNS
cord-010027-r0tl01kq	1969	17	arranged	arrange	VBN
cord-010027-r0tl01kq	1969	18	in	in	IN
cord-010027-r0tl01kq	1969	19	interlacing	interlace	VBG
cord-010027-r0tl01kq	1969	20	fascicles	fascicle	NNS
cord-010027-r0tl01kq	1969	21	in	in	IN
cord-010027-r0tl01kq	1969	22	collagenous	collagenous	JJ
cord-010027-r0tl01kq	1969	23	stroma	stroma	NNS
cord-010027-r0tl01kq	1969	24	and	and	CC
cord-010027-r0tl01kq	1969	25	numerous	numerous	JJ
cord-010027-r0tl01kq	1969	26	pink	pink	JJ
cord-010027-r0tl01kq	1969	27	intracytoplasmic	intracytoplasmic	JJ
cord-010027-r0tl01kq	1969	28	inclusions	inclusion	NNS
cord-010027-r0tl01kq	1969	29	.	.	.
cord-010027-r0tl01kq	1970	1	The	the	DT
cord-010027-r0tl01kq	1970	2	lesion	lesion	NN
cord-010027-r0tl01kq	1970	3	appeared	appear	VBD
cord-010027-r0tl01kq	1970	4	incompletely	incompletely	RB
cord-010027-r0tl01kq	1970	5	excised	excise	VBN
cord-010027-r0tl01kq	1970	6	and	and	CC
cord-010027-r0tl01kq	1970	7	the	the	DT
cord-010027-r0tl01kq	1970	8	patient	patient	NN
cord-010027-r0tl01kq	1970	9	will	will	MD
cord-010027-r0tl01kq	1970	10	be	be	VB
cord-010027-r0tl01kq	1970	11	kept	keep	VBN
cord-010027-r0tl01kq	1970	12	under	under	IN
cord-010027-r0tl01kq	1970	13	review	review	NN
cord-010027-r0tl01kq	1970	14	on	on	IN
cord-010027-r0tl01kq	1970	15	account	account	NN
cord-010027-r0tl01kq	1970	16	of	of	IN
cord-010027-r0tl01kq	1970	17	the	the	DT
cord-010027-r0tl01kq	1970	18	high	high	JJ
cord-010027-r0tl01kq	1970	19	risk	risk	NN
cord-010027-r0tl01kq	1970	20	of	of	IN
cord-010027-r0tl01kq	1970	21	recurrence	recurrence	NN
cord-010027-r0tl01kq	1970	22	.	.	.
cord-010027-r0tl01kq	1971	1	Decreased	decrease	VBN
cord-010027-r0tl01kq	1971	2	Expression	expression	NN
cord-010027-r0tl01kq	1971	3	of	of	IN
cord-010027-r0tl01kq	1971	4	the	the	DT
cord-010027-r0tl01kq	1971	5	Mitochondrial	Mitochondrial	NNP
cord-010027-r0tl01kq	1971	6	BCAT	BCAT	NNP
cord-010027-r0tl01kq	1971	7	Protein	Protein	NNP
cord-010027-r0tl01kq	1971	8	Correlates	correlate	VBZ
cord-010027-r0tl01kq	1971	9	with	with	IN
cord-010027-r0tl01kq	1971	10	Improved	Improved	NNP
cord-010027-r0tl01kq	1971	11	Patient	Patient	NNP
cord-010027-r0tl01kq	1971	12	Survival	Survival	NNP
cord-010027-r0tl01kq	1971	13	in	in	IN
cord-010027-r0tl01kq	1971	14	IDH	IDH	NNP
cord-010027-r0tl01kq	1971	15	Wild	Wild	NNP
cord-010027-r0tl01kq	1971	16	-	-	HYPH
cord-010027-r0tl01kq	1971	17	Type	type	NN
cord-010027-r0tl01kq	1971	18	Gliomas	Gliomas	NNP
cord-010027-r0tl01kq	1971	19	ME	ME	NNP
cord-010027-r0tl01kq	1971	20	Conway	Conway	NNP
cord-010027-r0tl01kq	1971	21	1	1	CD
cord-010027-r0tl01kq	1971	22	;	;	:
cord-010027-r0tl01kq	1971	23	J	J	NNP
cord-010027-r0tl01kq	1971	24	Hull	Hull	NNP
cord-010027-r0tl01kq	1971	25	1	1	CD
cord-010027-r0tl01kq	1971	26	;	;	:
cord-010027-r0tl01kq	1971	27	M	M	NNP
cord-010027-r0tl01kq	1971	28	El	El	NNP
cord-010027-r0tl01kq	1971	29	Hindy	Hindy	NNP
cord-010027-r0tl01kq	1971	30	1	1	CD
cord-010027-r0tl01kq	1971	31	;	;	:
cord-010027-r0tl01kq	1971	32	SC	SC	NNP
cord-010027-r0tl01kq	1971	33	Taylor	Taylor	NNP
cord-010027-r0tl01kq	1971	34	1	1	CD
cord-010027-r0tl01kq	1971	35	;	;	:
cord-010027-r0tl01kq	1971	36	F	F	NNP
cord-010027-r0tl01kq	1971	37	El	El	NNP
cord-010027-r0tl01kq	1971	38	Amraoui	Amraoui	NNP
cord-010027-r0tl01kq	1971	39	1	1	CD
cord-010027-r0tl01kq	1971	40	;	;	:
cord-010027-r0tl01kq	1971	41	C	C	NNP
cord-010027-r0tl01kq	1971	42	Paton	Paton	NNP
cord-010027-r0tl01kq	1971	43	-	-	HYPH
cord-010027-r0tl01kq	1971	44	Thomas	Thomas	NNP
cord-010027-r0tl01kq	1971	45	1	1	CD
cord-010027-r0tl01kq	1971	46	;	;	:
cord-010027-r0tl01kq	1971	47	P	p	NN
cord-010027-r0tl01kq	1971	48	White	white	JJ
cord-010027-r0tl01kq	1971	49	1	1	CD
cord-010027-r0tl01kq	1971	50	;	;	:
cord-010027-r0tl01kq	1971	51	M	M	NNP
cord-010027-r0tl01kq	1971	52	Williams	Williams	NNP
cord-010027-r0tl01kq	1971	53	2	2	CD
cord-010027-r0tl01kq	1971	54	;	;	:
cord-010027-r0tl01kq	1971	55	P	p	NN
cord-010027-r0tl01kq	1971	56	HR	HR	NNP
cord-010027-r0tl01kq	1971	57	Haynes	Haynes	NNP
cord-010027-r0tl01kq	1971	58	3	3	CD
cord-010027-r0tl01kq	1971	59	;	;	:
cord-010027-r0tl01kq	1971	60	SM	SM	NNP
cord-010027-r0tl01kq	1971	61	Hutson	Hutson	NNP
cord-010027-r0tl01kq	1971	62	4	4	CD
cord-010027-r0tl01kq	1971	63	;	;	:
cord-010027-r0tl01kq	1972	1	KM	KM	NNP
cord-010027-r0tl01kq	1972	2	Kurian	Kurian	NNP
cord-010027-r0tl01kq	1972	3	3	3	CD