id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006127-rl7rur2j	Brown, Nik	Regulating Hybrids: ‘Making a Mess’ and ‘Cleaning Up’ in Tissue Engineering and Transpecies Transplantation	2006-02-08		.txt	text/plain	8926	417	40	Developing a conceptual vocabulary for understanding the relationship between material and institutional hybrids, the paper compares human tissue engineering (TE) and xenotransplantation (XT), areas of innovation which regulators have sought to govern separately and in isolation from one another. Human and animal matters, cell cultures and tissue products have much greater corporeal connection than has been institutionally recognized, and are therefore a source of acute instability in the regulation of implants and transplants. While the troubled nature of transplantation has been relatively well documented (eg Swazey, 1978, 1992) , less well understood are new forms of innovation that cut across machines, humans and animals raising regulatory concerns about material and cultural risk (Brown and Michael, 2004; Faulkner et al., 2004; Kent et al., 2005) . The previous definition used by the FDA and the British regulatory body for XT (the United Kingdom Xenotransplantation Interim Regulatory Authority, 2003) did not account for production methods whereby human and animal tissues may be subject to 'ex-vivo contact' as is the case with Epicelt.	./cache/cord-006127-rl7rur2j.txt	./txt/cord-006127-rl7rur2j.txt