id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-275796-4560i8cx	Kumar, Prashant	Prophylactic and therapeutic approaches for human metapneumovirus	2018-10-20		.txt	text/plain	6555	311	37	Recently, 54G10, a human monoclonal antibody directed to a conserved epitope of HMPV fusion protein, was shown to be highly neutralizing and effective in decreasing the viral titre in lungs and nasal aspirates of infected HMPV permissive mice model. Prior to this, Fab DS7, a recombinant human monoclonal antibody fragment generated using phage display technology against a fusion protein epitope was evaluated and found to be significantly effective in restricting the propagation of HMPV in the lungs of cotton rats [106] . In past few years, nanoemulsion based inactivation of virus like RSV was demonstrated to yield safe vaccines which could induce effective humoral immune response and enhanced viral clearance from the host body [59] . demonstrated that recombinant bacillus Calmette-Guerin (rBCG) carrying the gene encoding HMPV P protein could successfully express the viral protein and immunization with the rBCG strain could induce a protective Th1 immunity in mice model by activation of virus specific T cells producing IFNc and IL-2 [72] .	./cache/cord-275796-4560i8cx.txt	./txt/cord-275796-4560i8cx.txt