id author title date pages extension mime words sentences flesch summary cache txt cord-006991-2q5ore6g Chi, X. Oral administration of tea saponins to relive oxidative stress and immune suppression in chickens 2017-06-15 .txt text/plain 5200 282 47 The results showed that administration of tea saponins significantly increased total antioxidant capacity, total superoxide dismutase, catalase, glutathione peroxidase, glutathione, ascorbic acid, and α-tocopherol, and decreased malondialdehyde and protein carbonyl. Enhanced immune responses, such as lymphocyte proliferation induced by concanavalin A and lipopolysaccharides, and serum Newcastle disease virusand infectious bronchitis virus-specific antibodies were also observed in chickens injected with or without cyclophosphamide. At the present study, we evaluated the effect of TS on the antioxidative activities as well as the immune responses to a live bivalent vaccine of Newcastle disease virus (NDV) and infectious bronchitis virus (IBV) vaccine in chickens in oxidative stress induced by cyclophosphamide (Cy). In this study, injection of Cy generated oxidative stress and lowered immune responses by reducing antioxidant enzymes such as T-AOC, T-SOD, GSH, and CAT, as well as inhibiting lymphocyte proliferation and antibody responses to vaccination. ./cache/cord-006991-2q5ore6g.txt ./txt/cord-006991-2q5ore6g.txt