id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-002011-u6dfp6gf	Toubiana, Julie	Association of REL polymorphisms and outcome of patients with septic shock	2016-04-08		.txt	text/plain	3956	200	47	CONCLUSION: In a large ICU population, we report a significant clinical association between a variation in the human REL gene and severity and mortality of septic shock, suggesting for the first time a new insight into the role of cRel in response to infection in humans. Hence, the present study aims to test the hypothesis of an association between clinically significant REL genetic variants and severity of septic shock in a large cohort of well-defined intensive care unit (ICU) patients. In order to study the link between REL SNPs and septic shock severity, we compared acute respiratory distress syndrome (ARDS) and MODS frequencies, and VFD value between patients carrying REL rs842647*G and rs13031237*T minor alleles and in those homozygous for the major alleles. This study was the first to investigate the importance of two polymorphisms within REL gene in a large European population of septic shock patients.	./cache/cord-002011-u6dfp6gf.txt	./txt/cord-002011-u6dfp6gf.txt