id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004427-dy9v9asg	Bissell, Brittany D.	Impact of protocolized diuresis for de-resuscitation in the intensive care unit	2020-02-28		.txt	text/plain	4699	242	37	Adult patients admitted to the Medical ICU receiving mechanical ventilation with either (1) clinical signs of volume overload via chest radiography or physical exam or (2) any cumulative fluid balance ≥ 0 mL since hospital admission were eligible for inclusion. Previous protocols guiding volume removal in the critically ill can be found in specific populations including acute decompensated heart failure, AKI, or RRT weaning, with protocolized approaches often improving clinical outcomes versus standard of care [9] [10] [11] . In this study, we aimed to evaluate the impact of a novel diuresis protocol utilizing common bedside monitoring parameters and simplified loop diuretic dosing on cumulative fluid balance over the first 72 h following hemodynamic stability, as compared to standard of care. Using a diuresis protocol for volume de-resuscitation, we demonstrated a significant decrease in net cumulative fluid balance at 72 h following shock resolution, with potential benefit on clinical outcomes including renal recovery, mortality, and ICU length of stay.	./cache/cord-004427-dy9v9asg.txt	./txt/cord-004427-dy9v9asg.txt