id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011327-zsoc4wec	Martin-Loeches, Ignacio	Antibiotic prophylaxis in the ICU: to be or not to be administered for patients undergoing procedures?	2019-11-28		.txt	text/plain	1973	95	27	However, SAP is also commonly practiced in many ICUs. A single-centre study conducted recently in a Belgian ICU showed that SAP and prophylaxis for immunocompromised patients constituted two-thirds of prophylactic antibiotic treatments prescribed [13] . There are no randomised controlled trials on the effects of timing or choice of antibiotic prophylaxis on the outcomes of ICU patients requiring unplanned surgical procedures. However, French guidelines for the prevention, diagnosis and treatment of hospital-acquired pneumonia in ICU suggest consideration of selective digestive decontamination with both topical and systemic antibiotics (for a maximum of 96 h) to decrease the rate of pneumonia immediately after urgent intubation based on indirect evidence from several studies [22] . A metaanalysis of studies focused on antibiotic prophylaxis for chest drain insertion in non-ICU patients (i.e. thoracic injury), concluded that treatment after chest drain insertion was significantly associated with a reduced risk of empyema (RR 0.25; 95% CI 0.13-0.49) and pneumonia (RR 0.41; 95% CI 0.24-0.71) when compared with placebo alone [28] .	./cache/cord-011327-zsoc4wec.txt	./txt/cord-011327-zsoc4wec.txt