id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-012560-p5s0p7fd	Decavèle, Maxens	One-year survival of patients with high-grade glioma discharged alive from the intensive care unit	2020-08-29		.txt	text/plain	3703	178	43	We sought to quantify 1-year mortality and evaluate the association between mortality and (1) functional status, and (2) management of anticancer therapy in patients with high-grade glioma discharged alive from the intensive care unit. On multivariate logistic regression analysis, two factors were independently associated with lower mortality 1 year after ICU admission: continuation of anticancer therapy after ICU discharge (OR 0.18, 95% CI 0.03-0.75, p = 0.028), and Karnofsky performance status at ICU admission (OR 0.90, 95% CI 0.85-0.95, p < 0.001). The main results of the study can be summarized as follows: in HGG patients discharged alive after an unplanned medical ICU stay (1), we observed a substantial proportion of survivors 1 year after ICU admission (more than one quarter of patients) and most of these patients exhibited relatively favorable performance status even 1 year after ICU admission, (2) continuation of anticancer therapy was possible in almost 50% of patients and was strongly associated with cancer progression and use of corticosteroids at admission, and (3) continuation of anticancer therapy and Karnofsky performance status at admission were associated with higher 1-year survival rates.	./cache/cord-012560-p5s0p7fd.txt	./txt/cord-012560-p5s0p7fd.txt