id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-023873-fidpskcs	Meersseman, Wouter	Invasive Aspergillosis in the Intensive Care Unit: Beyond the Typical Haematological Patient	2009-05-04		.txt	text/plain	4137	208	39	Finally, to date, the diagnostic utility of recently available non-culture based microbiological tools, including the detection of fungal antigens and the detection of Aspergillus-specific DNA through polymerase chain reaction (PCR) techniques, has not been properly validated in the non-haematology ICU population. In addition, typical ICU patients such as those with chronic obstructive pulmonary disease (COPD) or liver disorders were not considered amongst hosts at high risk for IA in the recently updated EORTC/MSG guidelines [2] . In a recent study published by our group [10] , patients with fever new lung infiltrates were screened for IA using galactomannan testing in bronchoalveolar (BAL) fluid. The concept that increasing fungal burden due to specific ICU treatments for other diseases than IA (e.g. steroids for septic shock) parallels the progression from subclinical to clinical aspergillosis, needs to be explored with more sensitive markers (e.g. PCR). Corticosteroid treatment as a risk factor for invasive aspergillosis in patients with lung disease	./cache/cord-023873-fidpskcs.txt	./txt/cord-023873-fidpskcs.txt