id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-028639-mk798t8f	Weeden, M.	Functional Outcomes in Patients Admitted to the Intensive Care Unit with Traumatic Brain Injury and Exposed to Hyperoxia: A Retrospective Multicentre Cohort Study	2020-07-06		.txt	text/plain	3733	190	49	title: Functional Outcomes in Patients Admitted to the Intensive Care Unit with Traumatic Brain Injury and Exposed to Hyperoxia: A Retrospective Multicentre Cohort Study Indeed, retrospective studies have raised concern about greater mortality with hyperoxia [6] [7] [8] , albeit a recent large, multicenter randomized controlled trial (ICU-ROX) demonstrated no effect of liberal oxygen exposure on ventilator-free days or mortality in a mixed intensive care unit (ICU) population [9] . In view of this knowledge gap, we designed a retrospective cohort study to explore the association between early hyperoxia (as measured by the partial arterial pressure of oxygen [P a O 2 ]) and 6, 12, and 24 months functional outcomes in ventilated TBI patients admitted to the ICU. In a large cohort study of TBI patients, managed in a comprehensive state-wide trauma system, we found no association between hyperoxia in the first 24-h of ICU admission, and adverse long-term functional outcomes.	./cache/cord-028639-mk798t8f.txt	./txt/cord-028639-mk798t8f.txt