id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-028923-gzqd5g0k	Vitug, Sarah	Sedation with ketamine and fentanyl combination improves patient outcomes in intensive care units	2020-07-10		.txt	text/plain	1067	64	32	title: Sedation with ketamine and fentanyl combination improves patient outcomes in intensive care units Psychological manifestations such as depression and suicidal ideation are commonly caused by poorly controlled pain, anxiety, and sleep deprivation in intensive care unit (ICU) patients. We have shown that appropriate combinations of ketamine and fentanyl are effective, and if further supplementation is needed, we utilize additional pharmacological agents in low doses and regional techniques that ultimately lower the overall opioid consumption. For the last 25 years, we have adopted a multimodal approach for pain and sedation, such as ketamine and fentanyl combinations for many of our postoperative ICU patients. In patients who are resistant to sedation, we add medication in addition to ketamine and fentanyl, such as low-dose propofol, midazolam, or dexmedetomidine [3] . The purpose of our multimodal approach to pain and sedation in the postoperative ICU setting is to improve the quality of care for our patients by minimizing undesired effects associated with analgesic agents.	./cache/cord-028923-gzqd5g0k.txt	./txt/cord-028923-gzqd5g0k.txt