id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-256533-slbfft33	Gomez Rial, J.	Increased serum levels of sCD14 and sCD163 indicate a preponderant role for monocytes in COVID-19 immunopathology	2020-06-04		.txt	text/plain	2854	187	43	Fifty-nine SARS-Cov-2 positive hospitalized patients, classified according to ICU or non-ICU admission requirement, were prospectively recruited and analyzed by ELISA for levels of sCD14 and sCD163, along with other laboratory parameters, and compared to a healthy control group. Fifty-nine SARS-Cov-2 positive hospitalized patients, classified according to ICU or non-ICU admission requirement, were prospectively recruited and analyzed by ELISA for levels of sCD14 and sCD163, along with other laboratory parameters, and compared to a healthy control group. Emerging evidence from SARS-Cov-2 infected patients suggests a key role for monocyte-macrophage in the immunopathology of COVID-19 infection, with a predominant monocyte-derived macrophage infiltration observed in severely damaged lungs [1] , and morphological and inflammation-related changes in peripheral blood monocytes that correlate with the patients' outcome [2] An overexuberant inflammatory immune response with production of a cytokine storm and T-cell immunosuppression are the main hallmarks of severity in these patients [3] .	./cache/cord-256533-slbfft33.txt	./txt/cord-256533-slbfft33.txt