id author title date pages extension mime words sentences flesch summary cache txt cord-263883-7ba0huwy Ansarin, Khalil Effect of bromhexine on clinical outcomes and mortality in COVID-19 patients: A randomized clinical trial 2020-07-19 .txt text/plain 3119 186 51 The present study aimed to evaluate the efficacy of bromhexine in intensive care unit (ICU) admission, mechanical ventilation, and mortality in patients with COVID-19. The current study, an open-label, randomized clinical trial, examined the efficacy of early start of oral bromhexine, in the intensive care unit (ICU) admission, rate of mechanical ventilation, and mortality in patients with COVID-19 pneumonia. The data presented in this clinical trial confirmed that the early-onset treatment with oral bromhexine 8 mg three times a day not only effectively mitigated the respiratory symptoms, but also significantly decreased the rate of ICU admissions, intubation, mechanical ventilation, and mortality in COVID-19 disease. The data analysis of this clinical trial also showed that cardinal respiratory symptoms (cough, lassitude, and dyspnea) in patients with COVID-19 disease who received bromhexine treatment was remarkably less than the standard group. ./cache/cord-263883-7ba0huwy.txt ./txt/cord-263883-7ba0huwy.txt