id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-285291-pep4opiq	Remy, Kenneth E.	Caring for Critically Ill Adults With Coronavirus Disease 2019 in a PICU: Recommendations by Dual Trained Intensivists*	2020-04-29		.txt	text/plain	7168	423	41	T he worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 has already resulted in critical care demands overwhelming resources in nations such as Italy (1) . Prone positioning for at least 12 hours daily in adults with severe ARDS may increase ventilator-free days, reduce in-hospital mortality, and reduce the need for rescue therapies like inhaled nitric oxide and extracorporeal membrane oxygenation (ECMO) (16, (65) (66) (67) (68) . Nonpharmacologic approaches to these modifiable risk factors include frequent environmental reorientation, cognitive stimulation, minimizing sleep interruptions, engaging familiar visitors, limiting use of sedative medications, and scheduled sedation "holidays." These strategies have consistently shown improved clinical outcomes in critically ill patients and are now considered standard of care (117) . EPVent-2 Study Group: Effect of titrating positive end-expiratory pressure (PEEP) with an esophageal pressure-guided strategy vs an empirical high PEEP-FIO 2 strategy on death and days free from mechanical ventilation among patients with acute respiratory distress syndrome: A randomized clinical trial	./cache/cord-285291-pep4opiq.txt	./txt/cord-285291-pep4opiq.txt