id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-318954-pj5lsvsa	Arabi, Yaseen	Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol	2015-11-19		.txt	text/plain	3963	203	48	title: Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol We aim to study the feasibility of CP therapy as well as its safety and clinical and laboratory effects in critically ill patients with MERS-CoV infection. In the CP therapy phase, 20 consecutive critically ill patients admitted to intensive care unit with laboratory-confirmed MERS-CoV infection will be enrolled and each will receive 2 units of CP. Post enrollment, patients will be followed for clinical and laboratory outcomes that include anti-MERS-CoV antibodies and viral load. Since seriously ill MERS-CoV-infected patients may have detectable viral RNA in various locations that can be sampled (for example lower respiratory tract secretions) for prolonged periods, it might be possible to first determine the relationship between neutralizing antibody dose and antiviral effects on clinical and laboratory features in a small open-label study.	./cache/cord-318954-pj5lsvsa.txt	./txt/cord-318954-pj5lsvsa.txt