id author title date pages extension mime words sentences flesch summary cache txt cord-326315-ncfxlnpj Cillóniz, Catia Community-acquired polymicrobial pneumonia in the intensive care unit: aetiology and prognosis 2011-09-14 .txt text/plain 4176 205 29 INTRODUCTION: The frequency and clinical significance of polymicrobial aetiology in community-acquired pneumonia (CAP) patients admitted to the ICU have been poorly studied. The aim of the present study was to describe the prevalence, clinical characteristics and outcomes of severe CAP of polymicrobial aetiology in patients admitted to the ICU. Patients with polymicrobial aetiology had previously received antibiotics less frequently, had a higher proportion of chronic respiratory and neurological diseases, less frequently presented fever at admission, had higher rates of PSI risk class V, had severe CAP according to the IDSA/ATS definition, and fulfilled ARDS criteria. Among these variables, chronic respiratory disease and ARDS criteria at hospital admission were independent predictors of polymicrobial aetiology in the multivariate analysis. • Polymicrobial aetiology is frequent among patients with CAP admitted to the ICU and may result in inappropriate empiric antimicrobial treatment. ./cache/cord-326315-ncfxlnpj.txt ./txt/cord-326315-ncfxlnpj.txt