id	sid	tid	token	lemma	pos
cord-009417-458rrhcm	1	1	key	key	JJ
cord-009417-458rrhcm	1	2	:	:	:
cord-009417-458rrhcm	1	3	cord-009417	cord-009417	NN
cord-009417-458rrhcm	1	4	-	-	HYPH
cord-009417-458rrhcm	1	5	458rrhcm	458rrhcm	NNP
cord-009417-458rrhcm	2	1	authors	author	NNS
cord-009417-458rrhcm	2	2	:	:	:
cord-009417-458rrhcm	2	3	Luce	Luce	NNP
cord-009417-458rrhcm	2	4	,	,	,
cord-009417-458rrhcm	2	5	Judith	Judith	NNP
cord-009417-458rrhcm	2	6	A.	a.	NN
cord-009417-458rrhcm	2	7	title	title	NN
cord-009417-458rrhcm	2	8	:	:	:
cord-009417-458rrhcm	2	9	Use	use	NN
cord-009417-458rrhcm	2	10	of	of	IN
cord-009417-458rrhcm	2	11	Blood	blood	NN
cord-009417-458rrhcm	2	12	Components	component	NNS
cord-009417-458rrhcm	2	13	in	in	IN
cord-009417-458rrhcm	2	14	the	the	DT
cord-009417-458rrhcm	2	15	Intensive	Intensive	NNP
cord-009417-458rrhcm	2	16	Care	Care	NNP
cord-009417-458rrhcm	2	17	Unit	Unit	NNP
cord-009417-458rrhcm	2	18	date	date	NN
cord-009417-458rrhcm	2	19	:	:	:
cord-009417-458rrhcm	2	20	2009	2009	CD
cord-009417-458rrhcm	2	21	-	-	SYM
cord-009417-458rrhcm	2	22	05	05	CD
cord-009417-458rrhcm	2	23	-	-	SYM
cord-009417-458rrhcm	2	24	15	15	CD
cord-009417-458rrhcm	2	25	journal	journal	NN
cord-009417-458rrhcm	2	26	:	:	:
cord-009417-458rrhcm	2	27	Critical	Critical	NNP
cord-009417-458rrhcm	2	28	Care	Care	NNP
cord-009417-458rrhcm	2	29	Medicine	medicine	NN
cord-009417-458rrhcm	2	30	DOI	doi	NN
cord-009417-458rrhcm	2	31	:	:	:
cord-009417-458rrhcm	2	32	10.1016	10.1016	CD
cord-009417-458rrhcm	2	33	/	/	SYM
cord-009417-458rrhcm	2	34	b978	b978	NN
cord-009417-458rrhcm	2	35	-	-	HYPH
cord-009417-458rrhcm	2	36	032304841	032304841	CD
cord-009417-458rrhcm	2	37	-	-	HYPH
cord-009417-458rrhcm	2	38	5.50082	5.50082	CD
cord-009417-458rrhcm	2	39	-	-	SYM
cord-009417-458rrhcm	2	40	0	0	CD
cord-009417-458rrhcm	2	41	sha	sha	NN
cord-009417-458rrhcm	2	42	:	:	:
cord-009417-458rrhcm	2	43	5589f09fd26e12ead3a4d85c63396f3ba964a437	5589f09fd26e12ead3a4d85c63396f3ba964a437	NNP
cord-009417-458rrhcm	2	44	doc_id	doc_id	CD
cord-009417-458rrhcm	2	45	:	:	:
cord-009417-458rrhcm	2	46	9417	9417	CD
cord-009417-458rrhcm	2	47	cord_uid	cord_uid	NNS
cord-009417-458rrhcm	2	48	:	:	:
cord-009417-458rrhcm	2	49	458rrhcm	458rrhcm	LS
cord-009417-458rrhcm	3	1	nan	nan	NNP
cord-009417-458rrhcm	3	2	Most	Most	JJS
cord-009417-458rrhcm	3	3	patients	patient	NNS
cord-009417-458rrhcm	3	4	admitted	admit	VBD
cord-009417-458rrhcm	3	5	to	to	IN
cord-009417-458rrhcm	3	6	an	an	DT
cord-009417-458rrhcm	3	7	intensive	intensive	JJ
cord-009417-458rrhcm	3	8	care	care	NN
cord-009417-458rrhcm	3	9	unit	unit	NN
cord-009417-458rrhcm	3	10	(	(	-LRB-
cord-009417-458rrhcm	3	11	ICU	ICU	NNP
cord-009417-458rrhcm	3	12	)	)	-RRB-
cord-009417-458rrhcm	3	13	require	require	VBP
cord-009417-458rrhcm	3	14	the	the	DT
cord-009417-458rrhcm	3	15	administration	administration	NN
cord-009417-458rrhcm	3	16	of	of	IN
cord-009417-458rrhcm	3	17	one	one	CD
cord-009417-458rrhcm	3	18	or	or	CC
cord-009417-458rrhcm	3	19	more	more	JJR
cord-009417-458rrhcm	3	20	blood	blood	NN
cord-009417-458rrhcm	3	21	components	component	NNS
cord-009417-458rrhcm	3	22	during	during	IN
cord-009417-458rrhcm	3	23	their	-PRON-	PRP$
cord-009417-458rrhcm	3	24	stay	stay	NN
cord-009417-458rrhcm	3	25	.	.	.
cord-009417-458rrhcm	4	1	Such	such	JJ
cord-009417-458rrhcm	4	2	patients	patient	NNS
cord-009417-458rrhcm	4	3	exhibit	exhibit	VBP
cord-009417-458rrhcm	4	4	great	great	JJ
cord-009417-458rrhcm	4	5	diversity	diversity	NN
cord-009417-458rrhcm	4	6	in	in	IN
cord-009417-458rrhcm	4	7	conditions	condition	NNS
cord-009417-458rrhcm	4	8	necessitating	necessitate	VBG
cord-009417-458rrhcm	4	9	care	care	NN
cord-009417-458rrhcm	4	10	in	in	IN
cord-009417-458rrhcm	4	11	the	the	DT
cord-009417-458rrhcm	4	12	ICU	ICU	NNP
cord-009417-458rrhcm	4	13	,	,	,
cord-009417-458rrhcm	4	14	age	age	NN
cord-009417-458rrhcm	4	15	,	,	,
cord-009417-458rrhcm	4	16	underlying	underlie	VBG
cord-009417-458rrhcm	4	17	medical	medical	JJ
cord-009417-458rrhcm	4	18	problems	problem	NNS
cord-009417-458rrhcm	4	19	,	,	,
cord-009417-458rrhcm	4	20	and	and	CC
cord-009417-458rrhcm	4	21	integrity	integrity	NN
cord-009417-458rrhcm	4	22	of	of	IN
cord-009417-458rrhcm	4	23	physiologic	physiologic	JJ
cord-009417-458rrhcm	4	24	compensatory	compensatory	JJ
cord-009417-458rrhcm	4	25	mechanisms	mechanism	NNS
cord-009417-458rrhcm	4	26	.	.	.
cord-009417-458rrhcm	5	1	All	all	PDT
cord-009417-458rrhcm	5	2	these	these	DT
cord-009417-458rrhcm	5	3	patients	patient	NNS
cord-009417-458rrhcm	5	4	,	,	,
cord-009417-458rrhcm	5	5	however	however	RB
cord-009417-458rrhcm	5	6	,	,	,
cord-009417-458rrhcm	5	7	share	share	VB
cord-009417-458rrhcm	5	8	the	the	DT
cord-009417-458rrhcm	5	9	need	need	NN
cord-009417-458rrhcm	5	10	for	for	IN
cord-009417-458rrhcm	5	11	optimized	optimize	VBN
cord-009417-458rrhcm	5	12	oxygen	oxygen	NN
cord-009417-458rrhcm	5	13	-	-	HYPH
cord-009417-458rrhcm	5	14	carrying	carry	VBG
cord-009417-458rrhcm	5	15	capacity	capacity	NN
cord-009417-458rrhcm	5	16	and	and	CC
cord-009417-458rrhcm	5	17	tissue	tissue	NN
cord-009417-458rrhcm	5	18	perfusion	perfusion	NN
cord-009417-458rrhcm	5	19	.	.	.
cord-009417-458rrhcm	6	1	Ongoing	ongoing	JJ
cord-009417-458rrhcm	6	2	blood	blood	NN
cord-009417-458rrhcm	6	3	loss	loss	NN
cord-009417-458rrhcm	6	4	resulting	result	VBG
cord-009417-458rrhcm	6	5	from	from	IN
cord-009417-458rrhcm	6	6	injuries	injury	NNS
cord-009417-458rrhcm	6	7	,	,	,
cord-009417-458rrhcm	6	8	surgical	surgical	JJ
cord-009417-458rrhcm	6	9	wounds	wound	NNS
cord-009417-458rrhcm	6	10	,	,	,
cord-009417-458rrhcm	6	11	invasive	invasive	JJ
cord-009417-458rrhcm	6	12	monitoring	monitoring	NN
cord-009417-458rrhcm	6	13	equipment	equipment	NN
cord-009417-458rrhcm	6	14	,	,	,
cord-009417-458rrhcm	6	15	and	and	CC
cord-009417-458rrhcm	6	16	blood	blood	NN
cord-009417-458rrhcm	6	17	sampling	sampling	NN
cord-009417-458rrhcm	6	18	requirements	requirement	NNS
cord-009417-458rrhcm	6	19	,	,	,
cord-009417-458rrhcm	6	20	coupled	couple	VBN
cord-009417-458rrhcm	6	21	with	with	IN
cord-009417-458rrhcm	6	22	inadequate	inadequate	JJ
cord-009417-458rrhcm	6	23	marrow	marrow	NN
cord-009417-458rrhcm	6	24	function	function	NN
cord-009417-458rrhcm	6	25	and	and	CC
cord-009417-458rrhcm	6	26	,	,	,
cord-009417-458rrhcm	6	27	in	in	IN
cord-009417-458rrhcm	6	28	some	some	DT
cord-009417-458rrhcm	6	29	,	,	,
cord-009417-458rrhcm	6	30	red	red	JJ
cord-009417-458rrhcm	6	31	cell	cell	NN
cord-009417-458rrhcm	6	32	destruction	destruction	NN
cord-009417-458rrhcm	6	33	,	,	,
cord-009417-458rrhcm	6	34	makes	make	VBZ
cord-009417-458rrhcm	6	35	red	red	JJ
cord-009417-458rrhcm	6	36	cell	cell	NN
cord-009417-458rrhcm	6	37	transfusion	transfusion	NN
cord-009417-458rrhcm	6	38	a	a	DT
cord-009417-458rrhcm	6	39	necessity	necessity	NN
cord-009417-458rrhcm	6	40	for	for	IN
cord-009417-458rrhcm	6	41	many	many	JJ
cord-009417-458rrhcm	6	42	ICU	ICU	NNP
cord-009417-458rrhcm	6	43	patients	patient	NNS
cord-009417-458rrhcm	6	44	.	.	.
cord-009417-458rrhcm	7	1	Additionally	additionally	RB
cord-009417-458rrhcm	7	2	,	,	,
cord-009417-458rrhcm	7	3	many	many	JJ
cord-009417-458rrhcm	7	4	patients	patient	NNS
cord-009417-458rrhcm	7	5	are	be	VBP
cord-009417-458rrhcm	7	6	susceptible	susceptible	JJ
cord-009417-458rrhcm	7	7	to	to	IN
cord-009417-458rrhcm	7	8	the	the	DT
cord-009417-458rrhcm	7	9	development	development	NN
cord-009417-458rrhcm	7	10	of	of	IN
cord-009417-458rrhcm	7	11	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	7	12	disorders	disorder	NNS
cord-009417-458rrhcm	7	13	requiring	require	VBG
cord-009417-458rrhcm	7	14	the	the	DT
cord-009417-458rrhcm	7	15	administration	administration	NN
cord-009417-458rrhcm	7	16	of	of	IN
cord-009417-458rrhcm	7	17	such	such	JJ
cord-009417-458rrhcm	7	18	blood	blood	NN
cord-009417-458rrhcm	7	19	components	component	NNS
cord-009417-458rrhcm	7	20	as	as	IN
cord-009417-458rrhcm	7	21	plasma	plasma	NN
cord-009417-458rrhcm	7	22	,	,	,
cord-009417-458rrhcm	7	23	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	7	24	,	,	,
cord-009417-458rrhcm	7	25	or	or	CC
cord-009417-458rrhcm	7	26	platelet	platelet	NN
cord-009417-458rrhcm	7	27	concentrates	concentrate	VBZ
cord-009417-458rrhcm	7	28	.	.	.
cord-009417-458rrhcm	8	1	Blood	blood	NN
cord-009417-458rrhcm	8	2	components	component	NNS
cord-009417-458rrhcm	8	3	should	should	MD
cord-009417-458rrhcm	8	4	be	be	VB
cord-009417-458rrhcm	8	5	considered	consider	VBN
cord-009417-458rrhcm	8	6	drugs	drug	NNS
cord-009417-458rrhcm	8	7	because	because	IN
cord-009417-458rrhcm	8	8	they	-PRON-	PRP
cord-009417-458rrhcm	8	9	exert	exert	VBP
cord-009417-458rrhcm	8	10	potent	potent	JJ
cord-009417-458rrhcm	8	11	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	8	12	responses	response	NNS
cord-009417-458rrhcm	8	13	yet	yet	RB
cord-009417-458rrhcm	8	14	are	be	VBP
cord-009417-458rrhcm	8	15	also	also	RB
cord-009417-458rrhcm	8	16	capable	capable	JJ
cord-009417-458rrhcm	8	17	of	of	IN
cord-009417-458rrhcm	8	18	causing	cause	VBG
cord-009417-458rrhcm	8	19	signifi	signifi	NNP
cord-009417-458rrhcm	8	20	ca	can	MD
cord-009417-458rrhcm	8	21	nt	not	RB
cord-009417-458rrhcm	8	22	adverse	adverse	JJ
cord-009417-458rrhcm	8	23	effects	effect	NNS
cord-009417-458rrhcm	8	24	.	.	.
cord-009417-458rrhcm	9	1	The	the	DT
cord-009417-458rrhcm	9	2	Food	Food	NNP
cord-009417-458rrhcm	9	3	and	and	CC
cord-009417-458rrhcm	9	4	Drug	Drug	NNP
cord-009417-458rrhcm	9	5	Administration	Administration	NNP
cord-009417-458rrhcm	9	6	(	(	-LRB-
cord-009417-458rrhcm	9	7	FDA	FDA	NNP
cord-009417-458rrhcm	9	8	)	)	-RRB-
cord-009417-458rrhcm	9	9	regulates	regulate	VBZ
cord-009417-458rrhcm	9	10	blood	blood	NN
cord-009417-458rrhcm	9	11	component	component	NN
cord-009417-458rrhcm	9	12	preparation	preparation	NN
cord-009417-458rrhcm	9	13	,	,	,
cord-009417-458rrhcm	9	14	testing	testing	NN
cord-009417-458rrhcm	9	15	,	,	,
cord-009417-458rrhcm	9	16	and	and	CC
cord-009417-458rrhcm	9	17	administration	administration	NN
cord-009417-458rrhcm	9	18	.	.	.
cord-009417-458rrhcm	10	1	1	1	LS
cord-009417-458rrhcm	11	1	Unlike	unlike	IN
cord-009417-458rrhcm	11	2	pharmaceutical	pharmaceutical	JJ
cord-009417-458rrhcm	11	3	agents	agent	NNS
cord-009417-458rrhcm	11	4	,	,	,
cord-009417-458rrhcm	11	5	however	however	RB
cord-009417-458rrhcm	11	6	,	,	,
cord-009417-458rrhcm	11	7	blood	blood	NN
cord-009417-458rrhcm	11	8	components	component	NNS
cord-009417-458rrhcm	11	9	have	have	VBP
cord-009417-458rrhcm	11	10	fewer	few	JJR
cord-009417-458rrhcm	11	11	objective	objective	JJ
cord-009417-458rrhcm	11	12	indications	indication	NNS
cord-009417-458rrhcm	11	13	for	for	IN
cord-009417-458rrhcm	11	14	use	use	NN
cord-009417-458rrhcm	11	15	and	and	CC
cord-009417-458rrhcm	11	16	no	no	DT
cord-009417-458rrhcm	11	17	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	11	18	index	index	NN
cord-009417-458rrhcm	11	19	relating	relate	VBG
cord-009417-458rrhcm	11	20	dose	dose	NN
cord-009417-458rrhcm	11	21	to	to	IN
cord-009417-458rrhcm	11	22	safety	safety	NN
cord-009417-458rrhcm	11	23	.	.	.
cord-009417-458rrhcm	12	1	It	-PRON-	PRP
cord-009417-458rrhcm	12	2	is	be	VBZ
cord-009417-458rrhcm	12	3	not	not	RB
cord-009417-458rrhcm	12	4	as	as	RB
cord-009417-458rrhcm	12	5	simple	simple	JJ
cord-009417-458rrhcm	12	6	to	to	TO
cord-009417-458rrhcm	12	7	monitor	monitor	VB
cord-009417-458rrhcm	12	8	the	the	DT
cord-009417-458rrhcm	12	9	effi	effi	NNP
cord-009417-458rrhcm	12	10	cacy	cacy	NNP
cord-009417-458rrhcm	12	11	and	and	CC
cord-009417-458rrhcm	12	12	continuing	continue	VBG
cord-009417-458rrhcm	12	13	need	need	NN
cord-009417-458rrhcm	12	14	for	for	IN
cord-009417-458rrhcm	12	15	a	a	DT
cord-009417-458rrhcm	12	16	blood	blood	NN
cord-009417-458rrhcm	12	17	component	component	NN
cord-009417-458rrhcm	12	18	as	as	IN
cord-009417-458rrhcm	12	19	it	-PRON-	PRP
cord-009417-458rrhcm	12	20	is	be	VBZ
cord-009417-458rrhcm	12	21	to	to	TO
cord-009417-458rrhcm	12	22	determine	determine	VB
cord-009417-458rrhcm	12	23	the	the	DT
cord-009417-458rrhcm	12	24	blood	blood	NN
cord-009417-458rrhcm	12	25	level	level	NN
cord-009417-458rrhcm	12	26	of	of	IN
cord-009417-458rrhcm	12	27	a	a	DT
cord-009417-458rrhcm	12	28	drug	drug	NN
cord-009417-458rrhcm	12	29	.	.	.
cord-009417-458rrhcm	13	1	In	in	IN
cord-009417-458rrhcm	13	2	addition	addition	NN
cord-009417-458rrhcm	13	3	,	,	,
cord-009417-458rrhcm	13	4	the	the	DT
cord-009417-458rrhcm	13	5	risks	risk	NNS
cord-009417-458rrhcm	13	6	associated	associate	VBN
cord-009417-458rrhcm	13	7	with	with	IN
cord-009417-458rrhcm	13	8	transfusion	transfusion	NN
cord-009417-458rrhcm	13	9	can	can	MD
cord-009417-458rrhcm	13	10	not	not	RB
cord-009417-458rrhcm	13	11	be	be	VB
cord-009417-458rrhcm	13	12	known	know	VBN
cord-009417-458rrhcm	13	13	in	in	IN
cord-009417-458rrhcm	13	14	advance	advance	NN
cord-009417-458rrhcm	13	15	and	and	CC
cord-009417-458rrhcm	13	16	may	may	MD
cord-009417-458rrhcm	13	17	be	be	VB
cord-009417-458rrhcm	13	18	lethal	lethal	JJ
cord-009417-458rrhcm	13	19	;	;	:
cord-009417-458rrhcm	13	20	such	such	JJ
cord-009417-458rrhcm	13	21	risks	risk	NNS
cord-009417-458rrhcm	13	22	include	include	VBP
cord-009417-458rrhcm	13	23	medical	medical	JJ
cord-009417-458rrhcm	13	24	errors	error	NNS
cord-009417-458rrhcm	13	25	,	,	,
cord-009417-458rrhcm	13	26	as	as	RB
cord-009417-458rrhcm	13	27	well	well	RB
cord-009417-458rrhcm	13	28	as	as	IN
cord-009417-458rrhcm	13	29	infectious	infectious	JJ
cord-009417-458rrhcm	13	30	and	and	CC
cord-009417-458rrhcm	13	31	immunologic	immunologic	JJ
cord-009417-458rrhcm	13	32	hazards	hazard	NNS
cord-009417-458rrhcm	13	33	.	.	.
cord-009417-458rrhcm	14	1	Unlike	unlike	IN
cord-009417-458rrhcm	14	2	pharmaceutical	pharmaceutical	JJ
cord-009417-458rrhcm	14	3	agents	agent	NNS
cord-009417-458rrhcm	14	4	,	,	,
cord-009417-458rrhcm	14	5	these	these	DT
cord-009417-458rrhcm	14	6	prescribed	prescribed	JJ
cord-009417-458rrhcm	14	7	products	product	NNS
cord-009417-458rrhcm	14	8	require	require	VBP
cord-009417-458rrhcm	14	9	documentation	documentation	NN
cord-009417-458rrhcm	14	10	of	of	IN
cord-009417-458rrhcm	14	11	patient	patient	JJ
cord-009417-458rrhcm	14	12	consent	consent	NN
cord-009417-458rrhcm	14	13	and	and	CC
cord-009417-458rrhcm	14	14	indication	indication	NN
cord-009417-458rrhcm	14	15	for	for	IN
cord-009417-458rrhcm	14	16	use	use	NN
cord-009417-458rrhcm	14	17	.	.	.
cord-009417-458rrhcm	15	1	Although	although	IN
cord-009417-458rrhcm	15	2	the	the	DT
cord-009417-458rrhcm	15	3	American	american	JJ
cord-009417-458rrhcm	15	4	blood	blood	NN
cord-009417-458rrhcm	15	5	supply	supply	NN
cord-009417-458rrhcm	15	6	is	be	VBZ
cord-009417-458rrhcm	15	7	now	now	RB
cord-009417-458rrhcm	15	8	safer	safe	JJR
cord-009417-458rrhcm	15	9	than	than	IN
cord-009417-458rrhcm	15	10	ever	ever	RB
cord-009417-458rrhcm	15	11	before	before	RB
cord-009417-458rrhcm	15	12	,	,	,
cord-009417-458rrhcm	15	13	zero	zero	CD
cord-009417-458rrhcm	15	14	-	-	HYPH
cord-009417-458rrhcm	15	15	risk	risk	NN
cord-009417-458rrhcm	15	16	transfusion	transfusion	NN
cord-009417-458rrhcm	15	17	is	be	VBZ
cord-009417-458rrhcm	15	18	not	not	RB
cord-009417-458rrhcm	15	19	achievable	achievable	JJ
cord-009417-458rrhcm	15	20	,	,	,
cord-009417-458rrhcm	15	21	even	even	RB
cord-009417-458rrhcm	15	22	if	if	IN
cord-009417-458rrhcm	15	23	blood	blood	NN
cord-009417-458rrhcm	15	24	components	component	NNS
cord-009417-458rrhcm	15	25	could	could	MD
cord-009417-458rrhcm	15	26	be	be	VB
cord-009417-458rrhcm	15	27	sterilized	sterilize	VBN
cord-009417-458rrhcm	15	28	.	.	.
cord-009417-458rrhcm	16	1	The	the	DT
cord-009417-458rrhcm	16	2	process	process	NN
cord-009417-458rrhcm	16	3	of	of	IN
cord-009417-458rrhcm	16	4	donor	donor	NN
cord-009417-458rrhcm	16	5	selection	selection	NN
cord-009417-458rrhcm	16	6	and	and	CC
cord-009417-458rrhcm	16	7	screening	screening	NN
cord-009417-458rrhcm	16	8	has	have	VBZ
cord-009417-458rrhcm	16	9	become	become	VBN
cord-009417-458rrhcm	16	10	increasingly	increasingly	RB
cord-009417-458rrhcm	16	11	stringent	stringent	JJ
cord-009417-458rrhcm	16	12	,	,	,
cord-009417-458rrhcm	16	13	an	an	DT
cord-009417-458rrhcm	16	14	evolution	evolution	NN
cord-009417-458rrhcm	16	15	that	that	WDT
cord-009417-458rrhcm	16	16	began	begin	VBD
cord-009417-458rrhcm	16	17	in	in	IN
cord-009417-458rrhcm	16	18	response	response	NN
cord-009417-458rrhcm	16	19	to	to	IN
cord-009417-458rrhcm	16	20	the	the	DT
cord-009417-458rrhcm	16	21	welldefi	welldefi	NNP
cord-009417-458rrhcm	16	22	ned	ned	XX
cord-009417-458rrhcm	16	23	risks	risk	NNS
cord-009417-458rrhcm	16	24	of	of	IN
cord-009417-458rrhcm	16	25	transfusion	transfusion	NN
cord-009417-458rrhcm	16	26	-	-	HYPH
cord-009417-458rrhcm	16	27	transmitted	transmit	VBN
cord-009417-458rrhcm	16	28	hepatitis	hepatitis	NN
cord-009417-458rrhcm	16	29	and	and	CC
cord-009417-458rrhcm	16	30	human	human	JJ
cord-009417-458rrhcm	16	31	immunodefi	immunodefi	NNP
cord-009417-458rrhcm	16	32	ciency	ciency	NNP
cord-009417-458rrhcm	16	33	virus	virus	NN
cord-009417-458rrhcm	16	34	(	(	-LRB-
cord-009417-458rrhcm	16	35	HIV	HIV	NNP
cord-009417-458rrhcm	16	36	)	)	-RRB-
cord-009417-458rrhcm	16	37	infection	infection	NN
cord-009417-458rrhcm	16	38	.	.	.
cord-009417-458rrhcm	17	1	Although	although	IN
cord-009417-458rrhcm	17	2	the	the	DT
cord-009417-458rrhcm	17	3	value	value	NN
cord-009417-458rrhcm	17	4	of	of	IN
cord-009417-458rrhcm	17	5	maximizing	maximize	VBG
cord-009417-458rrhcm	17	6	recipient	recipient	NN
cord-009417-458rrhcm	17	7	safety	safety	NN
cord-009417-458rrhcm	17	8	is	be	VBZ
cord-009417-458rrhcm	17	9	unarguable	unarguable	JJ
cord-009417-458rrhcm	17	10	,	,	,
cord-009417-458rrhcm	17	11	increasing	increase	VBG
cord-009417-458rrhcm	17	12	donor	donor	NN
cord-009417-458rrhcm	17	13	selectivity	selectivity	NN
cord-009417-458rrhcm	17	14	has	have	VBZ
cord-009417-458rrhcm	17	15	its	-PRON-	PRP$
cord-009417-458rrhcm	17	16	price	price	NN
cord-009417-458rrhcm	17	17	.	.	.
cord-009417-458rrhcm	18	1	As	as	IN
cord-009417-458rrhcm	18	2	more	more	JJR
cord-009417-458rrhcm	18	3	tests	test	NNS
cord-009417-458rrhcm	18	4	are	be	VBP
cord-009417-458rrhcm	18	5	added	add	VBN
cord-009417-458rrhcm	18	6	and	and	CC
cord-009417-458rrhcm	18	7	more	more	JJR
cord-009417-458rrhcm	18	8	conditions	condition	NNS
cord-009417-458rrhcm	18	9	placed	place	VBN
cord-009417-458rrhcm	18	10	on	on	IN
cord-009417-458rrhcm	18	11	the	the	DT
cord-009417-458rrhcm	18	12	donor	donor	NN
cord-009417-458rrhcm	18	13	,	,	,
cord-009417-458rrhcm	18	14	the	the	DT
cord-009417-458rrhcm	18	15	number	number	NN
cord-009417-458rrhcm	18	16	of	of	IN
cord-009417-458rrhcm	18	17	usable	usable	JJ
cord-009417-458rrhcm	18	18	donations	donation	NNS
cord-009417-458rrhcm	18	19	has	have	VBZ
cord-009417-458rrhcm	18	20	declined	decline	VBN
cord-009417-458rrhcm	18	21	.	.	.
cord-009417-458rrhcm	19	1	This	this	DT
cord-009417-458rrhcm	19	2	trend	trend	NN
cord-009417-458rrhcm	19	3	has	have	VBZ
cord-009417-458rrhcm	19	4	led	lead	VBN
cord-009417-458rrhcm	19	5	to	to	IN
cord-009417-458rrhcm	19	6	occasional	occasional	JJ
cord-009417-458rrhcm	19	7	regional	regional	JJ
cord-009417-458rrhcm	19	8	and	and	CC
cord-009417-458rrhcm	19	9	seasonal	seasonal	JJ
cord-009417-458rrhcm	19	10	blood	blood	NN
cord-009417-458rrhcm	19	11	shortages	shortage	NNS
cord-009417-458rrhcm	19	12	and	and	CC
cord-009417-458rrhcm	19	13	,	,	,
cord-009417-458rrhcm	19	14	rarely	rarely	RB
cord-009417-458rrhcm	19	15	,	,	,
cord-009417-458rrhcm	19	16	outright	outright	JJ
cord-009417-458rrhcm	19	17	inability	inability	NN
cord-009417-458rrhcm	19	18	to	to	TO
cord-009417-458rrhcm	19	19	provide	provide	VB
cord-009417-458rrhcm	19	20	certain	certain	JJ
cord-009417-458rrhcm	19	21	blood	blood	NN
cord-009417-458rrhcm	19	22	components	component	NNS
cord-009417-458rrhcm	19	23	.	.	.
cord-009417-458rrhcm	20	1	Clinicians	clinician	NNS
cord-009417-458rrhcm	20	2	who	who	WP
cord-009417-458rrhcm	20	3	prescribe	prescribe	VBP
cord-009417-458rrhcm	20	4	blood	blood	NN
cord-009417-458rrhcm	20	5	components	component	NNS
cord-009417-458rrhcm	20	6	must	must	MD
cord-009417-458rrhcm	20	7	be	be	VB
cord-009417-458rrhcm	20	8	aware	aware	JJ
cord-009417-458rrhcm	20	9	of	of	IN
cord-009417-458rrhcm	20	10	these	these	DT
cord-009417-458rrhcm	20	11	uncertainties	uncertainty	NNS
cord-009417-458rrhcm	20	12	in	in	IN
cord-009417-458rrhcm	20	13	availability	availability	NN
cord-009417-458rrhcm	20	14	and	and	CC
cord-009417-458rrhcm	20	15	contribute	contribute	VB
cord-009417-458rrhcm	20	16	by	by	IN
cord-009417-458rrhcm	20	17	using	use	VBG
cord-009417-458rrhcm	20	18	blood	blood	NN
cord-009417-458rrhcm	20	19	products	product	NNS
cord-009417-458rrhcm	20	20	appropriately	appropriately	RB
cord-009417-458rrhcm	20	21	while	while	IN
cord-009417-458rrhcm	20	22	the	the	DT
cord-009417-458rrhcm	20	23	national	national	JJ
cord-009417-458rrhcm	20	24	blood	blood	NN
cord-009417-458rrhcm	20	25	banking	banking	NN
cord-009417-458rrhcm	20	26	system	system	NN
cord-009417-458rrhcm	20	27	seeks	seek	VBZ
cord-009417-458rrhcm	20	28	strategies	strategy	NNS
cord-009417-458rrhcm	20	29	to	to	TO
cord-009417-458rrhcm	20	30	ensure	ensure	VB
cord-009417-458rrhcm	20	31	an	an	DT
cord-009417-458rrhcm	20	32	adequate	adequate	JJ
cord-009417-458rrhcm	20	33	,	,	,
cord-009417-458rrhcm	20	34	safe	safe	JJ
cord-009417-458rrhcm	20	35	blood	blood	NN
cord-009417-458rrhcm	20	36	supply	supply	NN
cord-009417-458rrhcm	20	37	.	.	.
cord-009417-458rrhcm	21	1	Donor	donor	NN
cord-009417-458rrhcm	21	2	screening	screening	NN
cord-009417-458rrhcm	21	3	strategies	strategy	NNS
cord-009417-458rrhcm	21	4	to	to	TO
cord-009417-458rrhcm	21	5	ensure	ensure	VB
cord-009417-458rrhcm	21	6	recipient	recipient	NN
cord-009417-458rrhcm	21	7	safety	safety	NN
cord-009417-458rrhcm	21	8	take	take	VBP
cord-009417-458rrhcm	21	9	several	several	JJ
cord-009417-458rrhcm	21	10	forms	form	NNS
cord-009417-458rrhcm	21	11	.	.	.
cord-009417-458rrhcm	22	1	1	1	CD
cord-009417-458rrhcm	22	2	,	,	,
cord-009417-458rrhcm	22	3	2	2	CD
cord-009417-458rrhcm	22	4	American	american	JJ
cord-009417-458rrhcm	22	5	blood	blood	NN
cord-009417-458rrhcm	22	6	donors	donor	NNS
cord-009417-458rrhcm	22	7	are	be	VBP
cord-009417-458rrhcm	22	8	voluntary	voluntary	JJ
cord-009417-458rrhcm	22	9	donors	donor	NNS
cord-009417-458rrhcm	22	10	;	;	:
cord-009417-458rrhcm	22	11	cash	cash	NN
cord-009417-458rrhcm	22	12	payment	payment	NN
cord-009417-458rrhcm	22	13	was	be	VBD
cord-009417-458rrhcm	22	14	eliminated	eliminate	VBN
cord-009417-458rrhcm	22	15	in	in	IN
cord-009417-458rrhcm	22	16	the	the	DT
cord-009417-458rrhcm	22	17	1970s	1970	NNS
cord-009417-458rrhcm	22	18	after	after	IN
cord-009417-458rrhcm	22	19	studies	study	NNS
cord-009417-458rrhcm	22	20	linked	link	VBD
cord-009417-458rrhcm	22	21	professional	professional	JJ
cord-009417-458rrhcm	22	22	donors	donor	NNS
cord-009417-458rrhcm	22	23	with	with	IN
cord-009417-458rrhcm	22	24	transmission	transmission	NN
cord-009417-458rrhcm	22	25	of	of	IN
cord-009417-458rrhcm	22	26	hepatitis	hepatitis	NN
cord-009417-458rrhcm	22	27	.	.	.
cord-009417-458rrhcm	23	1	Confi	Confi	NNP
cord-009417-458rrhcm	23	2	dential	dential	JJ
cord-009417-458rrhcm	23	3	questionnaires	questionnaire	NNS
cord-009417-458rrhcm	23	4	were	be	VBD
cord-009417-458rrhcm	23	5	initiated	initiate	VBN
cord-009417-458rrhcm	23	6	to	to	TO
cord-009417-458rrhcm	23	7	limit	limit	VB
cord-009417-458rrhcm	23	8	transmission	transmission	NN
cord-009417-458rrhcm	23	9	of	of	IN
cord-009417-458rrhcm	23	10	HIV	HIV	NNP
cord-009417-458rrhcm	23	11	and	and	CC
cord-009417-458rrhcm	23	12	hepatitis	hepatitis	NNP
cord-009417-458rrhcm	23	13	and	and	CC
cord-009417-458rrhcm	23	14	to	to	TO
cord-009417-458rrhcm	23	15	allow	allow	VB
cord-009417-458rrhcm	23	16	voluntary	voluntary	JJ
cord-009417-458rrhcm	23	17	self	self	NN
cord-009417-458rrhcm	23	18	-	-	HYPH
cord-009417-458rrhcm	23	19	exclusion	exclusion	NN
cord-009417-458rrhcm	23	20	and	and	CC
cord-009417-458rrhcm	23	21	involuntary	involuntary	JJ
cord-009417-458rrhcm	23	22	exclusion	exclusion	NN
cord-009417-458rrhcm	23	23	of	of	IN
cord-009417-458rrhcm	23	24	donors	donor	NNS
cord-009417-458rrhcm	23	25	who	who	WP
cord-009417-458rrhcm	23	26	pose	pose	VBP
cord-009417-458rrhcm	23	27	an	an	DT
cord-009417-458rrhcm	23	28	increased	increase	VBN
cord-009417-458rrhcm	23	29	risk	risk	NN
cord-009417-458rrhcm	23	30	of	of	IN
cord-009417-458rrhcm	23	31	transmitting	transmit	VBG
cord-009417-458rrhcm	23	32	infectious	infectious	JJ
cord-009417-458rrhcm	23	33	agents	agent	NNS
cord-009417-458rrhcm	23	34	.	.	.
cord-009417-458rrhcm	24	1	Multiple	multiple	JJ
cord-009417-458rrhcm	24	2	specifi	specifi	NN
cord-009417-458rrhcm	24	3	c	c	NN
cord-009417-458rrhcm	24	4	serologic	serologic	NN
cord-009417-458rrhcm	24	5	and	and	CC
cord-009417-458rrhcm	24	6	biochemical	biochemical	JJ
cord-009417-458rrhcm	24	7	tests	test	NNS
cord-009417-458rrhcm	24	8	are	be	VBP
cord-009417-458rrhcm	24	9	performed	perform	VBN
cord-009417-458rrhcm	24	10	to	to	TO
cord-009417-458rrhcm	24	11	detect	detect	VB
cord-009417-458rrhcm	24	12	the	the	DT
cord-009417-458rrhcm	24	13	potential	potential	NN
cord-009417-458rrhcm	24	14	for	for	IN
cord-009417-458rrhcm	24	15	transmission	transmission	NN
cord-009417-458rrhcm	24	16	of	of	IN
cord-009417-458rrhcm	24	17	HIV	HIV	NNP
cord-009417-458rrhcm	24	18	and	and	CC
cord-009417-458rrhcm	24	19	other	other	JJ
cord-009417-458rrhcm	24	20	retroviruses	retrovirus	NNS
cord-009417-458rrhcm	24	21	,	,	,
cord-009417-458rrhcm	24	22	hepatitis	hepatitis	NN
cord-009417-458rrhcm	24	23	,	,	,
cord-009417-458rrhcm	24	24	and	and	CC
cord-009417-458rrhcm	24	25	syphilis	syphili	NNS
cord-009417-458rrhcm	24	26	.	.	.
cord-009417-458rrhcm	25	1	Any	any	DT
cord-009417-458rrhcm	25	2	donor	donor	NN
cord-009417-458rrhcm	25	3	who	who	WP
cord-009417-458rrhcm	25	4	indicates	indicate	VBZ
cord-009417-458rrhcm	25	5	high	high	JJ
cord-009417-458rrhcm	25	6	-	-	HYPH
cord-009417-458rrhcm	25	7	risk	risk	NN
cord-009417-458rrhcm	25	8	behavior	behavior	NN
cord-009417-458rrhcm	25	9	or	or	CC
cord-009417-458rrhcm	25	10	who	who	WP
cord-009417-458rrhcm	25	11	tests	test	VBZ
cord-009417-458rrhcm	25	12	repeatedly	repeatedly	RB
cord-009417-458rrhcm	25	13	positive	positive	JJ
cord-009417-458rrhcm	25	14	is	be	VBZ
cord-009417-458rrhcm	25	15	placed	place	VBN
cord-009417-458rrhcm	25	16	on	on	IN
cord-009417-458rrhcm	25	17	a	a	DT
cord-009417-458rrhcm	25	18	permanent	permanent	JJ
cord-009417-458rrhcm	25	19	deferral	deferral	NN
cord-009417-458rrhcm	25	20	list	list	NN
cord-009417-458rrhcm	25	21	.	.	.
cord-009417-458rrhcm	26	1	Some	some	DT
cord-009417-458rrhcm	26	2	patients	patient	NNS
cord-009417-458rrhcm	26	3	may	may	MD
cord-009417-458rrhcm	26	4	insist	insist	VB
cord-009417-458rrhcm	26	5	on	on	IN
cord-009417-458rrhcm	26	6	blood	blood	NN
cord-009417-458rrhcm	26	7	obtained	obtain	VBN
cord-009417-458rrhcm	26	8	from	from	IN
cord-009417-458rrhcm	26	9	relatives	relative	NNS
cord-009417-458rrhcm	26	10	or	or	CC
cord-009417-458rrhcm	26	11	friends	friend	NNS
cord-009417-458rrhcm	26	12	.	.	.
cord-009417-458rrhcm	27	1	This	this	DT
cord-009417-458rrhcm	27	2	practice	practice	NN
cord-009417-458rrhcm	27	3	is	be	VBZ
cord-009417-458rrhcm	27	4	termed	term	VBN
cord-009417-458rrhcm	27	5	directed	direct	VBN
cord-009417-458rrhcm	27	6	or	or	CC
cord-009417-458rrhcm	27	7	designated	designate	VBN
cord-009417-458rrhcm	27	8	donation	donation	NN
cord-009417-458rrhcm	27	9	.	.	.
cord-009417-458rrhcm	28	1	These	these	DT
cord-009417-458rrhcm	28	2	selected	select	VBN
cord-009417-458rrhcm	28	3	donors	donor	NNS
cord-009417-458rrhcm	28	4	must	must	MD
cord-009417-458rrhcm	28	5	undergo	undergo	VB
cord-009417-458rrhcm	28	6	the	the	DT
cord-009417-458rrhcm	28	7	same	same	JJ
cord-009417-458rrhcm	28	8	rigorous	rigorous	JJ
cord-009417-458rrhcm	28	9	questioning	questioning	NN
cord-009417-458rrhcm	28	10	and	and	CC
cord-009417-458rrhcm	28	11	testing	testing	NN
cord-009417-458rrhcm	28	12	as	as	IN
cord-009417-458rrhcm	28	13	volunteer	volunteer	NN
cord-009417-458rrhcm	28	14	donors	donor	NNS
cord-009417-458rrhcm	28	15	.	.	.
cord-009417-458rrhcm	29	1	Some	some	DT
cord-009417-458rrhcm	29	2	studies	study	NNS
cord-009417-458rrhcm	29	3	have	have	VBP
cord-009417-458rrhcm	29	4	found	find	VBN
cord-009417-458rrhcm	29	5	an	an	DT
cord-009417-458rrhcm	29	6	increased	increase	VBN
cord-009417-458rrhcm	29	7	frequency	frequency	NN
cord-009417-458rrhcm	29	8	of	of	IN
cord-009417-458rrhcm	29	9	hepatitis	hepatitis	NN
cord-009417-458rrhcm	29	10	markers	marker	NNS
cord-009417-458rrhcm	29	11	in	in	IN
cord-009417-458rrhcm	29	12	the	the	DT
cord-009417-458rrhcm	29	13	blood	blood	NN
cord-009417-458rrhcm	29	14	of	of	IN
cord-009417-458rrhcm	29	15	directed	direct	VBN
cord-009417-458rrhcm	29	16	donors	donor	NNS
cord-009417-458rrhcm	29	17	when	when	WRB
cord-009417-458rrhcm	29	18	compared	compare	VBN
cord-009417-458rrhcm	29	19	with	with	IN
cord-009417-458rrhcm	29	20	blood	blood	NN
cord-009417-458rrhcm	29	21	drawn	draw	VBN
cord-009417-458rrhcm	29	22	from	from	IN
cord-009417-458rrhcm	29	23	unselected	unselected	JJ
cord-009417-458rrhcm	29	24	volunteers	volunteer	NNS
cord-009417-458rrhcm	29	25	,	,	,
cord-009417-458rrhcm	29	26	but	but	CC
cord-009417-458rrhcm	29	27	others	other	NNS
cord-009417-458rrhcm	29	28	suggest	suggest	VBP
cord-009417-458rrhcm	29	29	that	that	IN
cord-009417-458rrhcm	29	30	designated	designate	VBN
cord-009417-458rrhcm	29	31	donors	donor	NNS
cord-009417-458rrhcm	29	32	may	may	MD
cord-009417-458rrhcm	29	33	be	be	VB
cord-009417-458rrhcm	29	34	no	no	RB
cord-009417-458rrhcm	29	35	different	different	JJ
cord-009417-458rrhcm	29	36	from	from	IN
cord-009417-458rrhcm	29	37	new	new	JJ
cord-009417-458rrhcm	29	38	volunteers	volunteer	NNS
cord-009417-458rrhcm	29	39	.	.	.
cord-009417-458rrhcm	30	1	3	3	CD
cord-009417-458rrhcm	30	2	,	,	,
cord-009417-458rrhcm	30	3	4	4	CD
cord-009417-458rrhcm	30	4	There	there	EX
cord-009417-458rrhcm	30	5	continues	continue	VBZ
cord-009417-458rrhcm	30	6	to	to	TO
cord-009417-458rrhcm	30	7	be	be	VB
cord-009417-458rrhcm	30	8	no	no	DT
cord-009417-458rrhcm	30	9	consensus	consensus	NN
cord-009417-458rrhcm	30	10	about	about	IN
cord-009417-458rrhcm	30	11	whether	whether	IN
cord-009417-458rrhcm	30	12	directed	direct	VBN
cord-009417-458rrhcm	30	13	donors	donor	NNS
cord-009417-458rrhcm	30	14	are	be	VBP
cord-009417-458rrhcm	30	15	,	,	,
cord-009417-458rrhcm	30	16	as	as	IN
cord-009417-458rrhcm	30	17	a	a	DT
cord-009417-458rrhcm	30	18	group	group	NN
cord-009417-458rrhcm	30	19	,	,	,
cord-009417-458rrhcm	30	20	as	as	RB
cord-009417-458rrhcm	30	21	safe	safe	JJ
cord-009417-458rrhcm	30	22	as	as	IN
cord-009417-458rrhcm	30	23	volunteer	volunteer	NN
cord-009417-458rrhcm	30	24	donors	donor	NNS
cord-009417-458rrhcm	30	25	.	.	.
cord-009417-458rrhcm	31	1	5	5	LS
cord-009417-458rrhcm	31	2	,	,	,
cord-009417-458rrhcm	31	3	6	6	CD
cord-009417-458rrhcm	31	4	Institutional	institutional	JJ
cord-009417-458rrhcm	31	5	policies	policy	NNS
cord-009417-458rrhcm	31	6	about	about	IN
cord-009417-458rrhcm	31	7	the	the	DT
cord-009417-458rrhcm	31	8	acceptability	acceptability	NN
cord-009417-458rrhcm	31	9	and	and	CC
cord-009417-458rrhcm	31	10	processing	processing	NN
cord-009417-458rrhcm	31	11	of	of	IN
cord-009417-458rrhcm	31	12	directed	direct	VBN
cord-009417-458rrhcm	31	13	donations	donation	NNS
cord-009417-458rrhcm	31	14	vary	vary	VBP
cord-009417-458rrhcm	31	15	widely	widely	RB
cord-009417-458rrhcm	31	16	.	.	.
cord-009417-458rrhcm	32	1	In	in	IN
cord-009417-458rrhcm	32	2	any	any	DT
cord-009417-458rrhcm	32	3	case	case	NN
cord-009417-458rrhcm	32	4	,	,	,
cord-009417-458rrhcm	32	5	supporting	support	VBG
cord-009417-458rrhcm	32	6	ICU	ICU	NNP
cord-009417-458rrhcm	32	7	patients	patient	NNS
cord-009417-458rrhcm	32	8	who	who	WP
cord-009417-458rrhcm	32	9	require	require	VBP
cord-009417-458rrhcm	32	10	large	large	JJ
cord-009417-458rrhcm	32	11	-	-	HYPH
cord-009417-458rrhcm	32	12	volume	volume	NN
cord-009417-458rrhcm	32	13	transfusion	transfusion	NN
cord-009417-458rrhcm	32	14	with	with	IN
cord-009417-458rrhcm	32	15	directed	direct	VBN
cord-009417-458rrhcm	32	16	donations	donation	NNS
cord-009417-458rrhcm	32	17	is	be	VBZ
cord-009417-458rrhcm	32	18	unlikely	unlikely	JJ
cord-009417-458rrhcm	32	19	to	to	TO
cord-009417-458rrhcm	32	20	be	be	VB
cord-009417-458rrhcm	32	21	advantageous	advantageous	JJ
cord-009417-458rrhcm	32	22	or	or	CC
cord-009417-458rrhcm	32	23	practical	practical	JJ
cord-009417-458rrhcm	32	24	.	.	.
cord-009417-458rrhcm	33	1	The	the	DT
cord-009417-458rrhcm	33	2	basic	basic	JJ
cord-009417-458rrhcm	33	3	principle	principle	NN
cord-009417-458rrhcm	33	4	of	of	IN
cord-009417-458rrhcm	33	5	blood	blood	NN
cord-009417-458rrhcm	33	6	component	component	NN
cord-009417-458rrhcm	33	7	therapy	therapy	NN
cord-009417-458rrhcm	33	8	is	be	VBZ
cord-009417-458rrhcm	33	9	prescription	prescription	NN
cord-009417-458rrhcm	33	10	of	of	IN
cord-009417-458rrhcm	33	11	the	the	DT
cord-009417-458rrhcm	33	12	specifi	specifi	NN
cord-009417-458rrhcm	33	13	c	c	SYM
cord-009417-458rrhcm	33	14	blood	blood	NN
cord-009417-458rrhcm	33	15	product	product	NN
cord-009417-458rrhcm	33	16	needed	need	VBN
cord-009417-458rrhcm	33	17	to	to	TO
cord-009417-458rrhcm	33	18	meet	meet	VB
cord-009417-458rrhcm	33	19	the	the	DT
cord-009417-458rrhcm	33	20	patient	patient	NN
cord-009417-458rrhcm	33	21	's	's	POS
cord-009417-458rrhcm	33	22	requirement	requirement	NN
cord-009417-458rrhcm	33	23	.	.	.
cord-009417-458rrhcm	34	1	A	a	DT
cord-009417-458rrhcm	34	2	single	single	JJ
cord-009417-458rrhcm	34	3	whole	whole	JJ
cord-009417-458rrhcm	34	4	blood	blood	NN
cord-009417-458rrhcm	34	5	(	(	-LRB-
cord-009417-458rrhcm	34	6	WB	WB	NNP
cord-009417-458rrhcm	34	7	)	)	-RRB-
cord-009417-458rrhcm	34	8	donation	donation	NN
cord-009417-458rrhcm	34	9	can	can	MD
cord-009417-458rrhcm	34	10	be	be	VB
cord-009417-458rrhcm	34	11	separated	separate	VBN
cord-009417-458rrhcm	34	12	into	into	IN
cord-009417-458rrhcm	34	13	its	-PRON-	PRP$
cord-009417-458rrhcm	34	14	composite	composite	JJ
cord-009417-458rrhcm	34	15	parts	part	NNS
cord-009417-458rrhcm	34	16	,	,	,
cord-009417-458rrhcm	34	17	or	or	CC
cord-009417-458rrhcm	34	18	components	component	NNS
cord-009417-458rrhcm	34	19	,	,	,
cord-009417-458rrhcm	34	20	which	which	WDT
cord-009417-458rrhcm	34	21	can	can	MD
cord-009417-458rrhcm	34	22	be	be	VB
cord-009417-458rrhcm	34	23	distributed	distribute	VBN
cord-009417-458rrhcm	34	24	to	to	IN
cord-009417-458rrhcm	34	25	several	several	JJ
cord-009417-458rrhcm	34	26	recipients	recipient	NNS
cord-009417-458rrhcm	34	27	with	with	IN
cord-009417-458rrhcm	34	28	differing	differ	VBG
cord-009417-458rrhcm	34	29	physiologic	physiologic	JJ
cord-009417-458rrhcm	34	30	needs	need	NNS
cord-009417-458rrhcm	34	31	.	.	.
cord-009417-458rrhcm	35	1	Component	component	NN
cord-009417-458rrhcm	35	2	therapy	therapy	NN
cord-009417-458rrhcm	35	3	thus	thus	RB
cord-009417-458rrhcm	35	4	meets	meet	VBZ
cord-009417-458rrhcm	35	5	the	the	DT
cord-009417-458rrhcm	35	6	clinical	clinical	JJ
cord-009417-458rrhcm	35	7	requirements	requirement	NNS
cord-009417-458rrhcm	35	8	of	of	IN
cord-009417-458rrhcm	35	9	increased	increase	VBN
cord-009417-458rrhcm	35	10	safety	safety	NN
cord-009417-458rrhcm	35	11	,	,	,
cord-009417-458rrhcm	35	12	efficacy	efficacy	NN
cord-009417-458rrhcm	35	13	,	,	,
cord-009417-458rrhcm	35	14	and	and	CC
cord-009417-458rrhcm	35	15	conservation	conservation	NN
cord-009417-458rrhcm	35	16	of	of	IN
cord-009417-458rrhcm	35	17	limited	limited	JJ
cord-009417-458rrhcm	35	18	resources	resource	NNS
cord-009417-458rrhcm	35	19	.	.	.
cord-009417-458rrhcm	36	1	As	as	IN
cord-009417-458rrhcm	36	2	the	the	DT
cord-009417-458rrhcm	36	3	variety	variety	NN
cord-009417-458rrhcm	36	4	of	of	IN
cord-009417-458rrhcm	36	5	blood	blood	NN
cord-009417-458rrhcm	36	6	product	product	NN
cord-009417-458rrhcm	36	7	components	component	NNS
cord-009417-458rrhcm	36	8	increases	increase	NNS
cord-009417-458rrhcm	36	9	,	,	,
cord-009417-458rrhcm	36	10	however	however	RB
cord-009417-458rrhcm	36	11	,	,	,
cord-009417-458rrhcm	36	12	the	the	DT
cord-009417-458rrhcm	36	13	complexity	complexity	NN
cord-009417-458rrhcm	36	14	of	of	IN
cord-009417-458rrhcm	36	15	transfusion	transfusion	NN
cord-009417-458rrhcm	36	16	medicine	medicine	NN
cord-009417-458rrhcm	36	17	also	also	RB
cord-009417-458rrhcm	36	18	increases	increase	VBZ
cord-009417-458rrhcm	36	19	.	.	.
cord-009417-458rrhcm	37	1	A	a	DT
cord-009417-458rrhcm	37	2	WB	WB	NNP
cord-009417-458rrhcm	37	3	donation	donation	NN
cord-009417-458rrhcm	37	4	is	be	VBZ
cord-009417-458rrhcm	37	5	typically	typically	RB
cord-009417-458rrhcm	37	6	separated	separate	VBN
cord-009417-458rrhcm	37	7	into	into	IN
cord-009417-458rrhcm	37	8	red	red	JJ
cord-009417-458rrhcm	37	9	blood	blood	NN
cord-009417-458rrhcm	37	10	cells	cell	NNS
cord-009417-458rrhcm	37	11	(	(	-LRB-
cord-009417-458rrhcm	37	12	RBCs	rbc	NNS
cord-009417-458rrhcm	37	13	)	)	-RRB-
cord-009417-458rrhcm	37	14	,	,	,
cord-009417-458rrhcm	37	15	a	a	DT
cord-009417-458rrhcm	37	16	platelet	platelet	NN
cord-009417-458rrhcm	37	17	concentrate	concentrate	NN
cord-009417-458rrhcm	37	18	,	,	,
cord-009417-458rrhcm	37	19	and	and	CC
cord-009417-458rrhcm	37	20	fresh	fresh	JJ
cord-009417-458rrhcm	37	21	frozen	frozen	JJ
cord-009417-458rrhcm	37	22	plasma	plasma	NN
cord-009417-458rrhcm	37	23	(	(	-LRB-
cord-009417-458rrhcm	37	24	FFP	FFP	NNP
cord-009417-458rrhcm	37	25	)	)	-RRB-
cord-009417-458rrhcm	37	26	within	within	IN
cord-009417-458rrhcm	37	27	hours	hour	NNS
cord-009417-458rrhcm	37	28	of	of	IN
cord-009417-458rrhcm	37	29	its	-PRON-	PRP$
cord-009417-458rrhcm	37	30	collection	collection	NN
cord-009417-458rrhcm	37	31	.	.	.
cord-009417-458rrhcm	38	1	The	the	DT
cord-009417-458rrhcm	38	2	plasma	plasma	NN
cord-009417-458rrhcm	38	3	may	may	MD
cord-009417-458rrhcm	38	4	be	be	VB
cord-009417-458rrhcm	38	5	further	further	RB
cord-009417-458rrhcm	38	6	processed	process	VBN
cord-009417-458rrhcm	38	7	into	into	IN
cord-009417-458rrhcm	38	8	cryoprecipitate	cryoprecipitate	NN
cord-009417-458rrhcm	38	9	and	and	CC
cord-009417-458rrhcm	38	10	supernatant	supernatant	JJ
cord-009417-458rrhcm	38	11	(	(	-LRB-
cord-009417-458rrhcm	38	12	cryopoor	cryopoor	NNP
cord-009417-458rrhcm	38	13	)	)	-RRB-
cord-009417-458rrhcm	38	14	plasma	plasma	NN
cord-009417-458rrhcm	38	15	.	.	.
cord-009417-458rrhcm	39	1	One	one	CD
cord-009417-458rrhcm	39	2	unit	unit	NN
cord-009417-458rrhcm	39	3	of	of	IN
cord-009417-458rrhcm	39	4	WB	WB	NNP
cord-009417-458rrhcm	39	5	measures	measure	NNS
cord-009417-458rrhcm	39	6	approximately	approximately	RB
cord-009417-458rrhcm	39	7	500	500	CD
cord-009417-458rrhcm	39	8	mL	ml	NN
cord-009417-458rrhcm	39	9	,	,	,
cord-009417-458rrhcm	39	10	including	include	VBG
cord-009417-458rrhcm	39	11	63	63	CD
cord-009417-458rrhcm	39	12	mL	mL	NNS
cord-009417-458rrhcm	39	13	of	of	IN
cord-009417-458rrhcm	39	14	citrate	citrate	NN
cord-009417-458rrhcm	39	15	anticoagulant	anticoagulant	NN
cord-009417-458rrhcm	39	16	/	/	SYM
cord-009417-458rrhcm	39	17	preservative	preservative	NN
cord-009417-458rrhcm	39	18	solution	solution	NN
cord-009417-458rrhcm	39	19	.	.	.
cord-009417-458rrhcm	40	1	Each	each	DT
cord-009417-458rrhcm	40	2	unit	unit	NN
cord-009417-458rrhcm	40	3	of	of	IN
cord-009417-458rrhcm	40	4	WB	WB	NNP
cord-009417-458rrhcm	40	5	supplies	supply	VBZ
cord-009417-458rrhcm	40	6	about	about	RB
cord-009417-458rrhcm	40	7	200	200	CD
cord-009417-458rrhcm	40	8	mL	ml	NN
cord-009417-458rrhcm	40	9	of	of	IN
cord-009417-458rrhcm	40	10	RBCs	rbc	NNS
cord-009417-458rrhcm	40	11	and	and	CC
cord-009417-458rrhcm	40	12	300	300	CD
cord-009417-458rrhcm	40	13	mL	ml	NN
cord-009417-458rrhcm	40	14	of	of	IN
cord-009417-458rrhcm	40	15	plasma	plasma	NN
cord-009417-458rrhcm	40	16	for	for	IN
cord-009417-458rrhcm	40	17	volume	volume	NN
cord-009417-458rrhcm	40	18	replacement	replacement	NN
cord-009417-458rrhcm	40	19	.	.	.
cord-009417-458rrhcm	41	1	WB	WB	NNP
cord-009417-458rrhcm	41	2	is	be	VBZ
cord-009417-458rrhcm	41	3	refrigerated	refrigerate	VBN
cord-009417-458rrhcm	41	4	for	for	IN
cord-009417-458rrhcm	41	5	21	21	CD
cord-009417-458rrhcm	41	6	to	to	TO
cord-009417-458rrhcm	41	7	35	35	CD
cord-009417-458rrhcm	41	8	days	day	NNS
cord-009417-458rrhcm	41	9	,	,	,
cord-009417-458rrhcm	41	10	depending	depend	VBG
cord-009417-458rrhcm	41	11	on	on	IN
cord-009417-458rrhcm	41	12	the	the	DT
cord-009417-458rrhcm	41	13	preservative	preservative	NN
cord-009417-458rrhcm	41	14	used	use	VBN
cord-009417-458rrhcm	41	15	.	.	.
cord-009417-458rrhcm	42	1	After	after	IN
cord-009417-458rrhcm	42	2	less	less	JJR
cord-009417-458rrhcm	42	3	than	than	IN
cord-009417-458rrhcm	42	4	24	24	CD
cord-009417-458rrhcm	42	5	hours	hour	NNS
cord-009417-458rrhcm	42	6	of	of	IN
cord-009417-458rrhcm	42	7	refrigerated	refrigerated	JJ
cord-009417-458rrhcm	42	8	storage	storage	NN
cord-009417-458rrhcm	42	9	in	in	IN
cord-009417-458rrhcm	42	10	this	this	DT
cord-009417-458rrhcm	42	11	preservative	preservative	NN
cord-009417-458rrhcm	42	12	and	and	CC
cord-009417-458rrhcm	42	13	bag	bag	NN
cord-009417-458rrhcm	42	14	system	system	NN
cord-009417-458rrhcm	42	15	,	,	,
cord-009417-458rrhcm	42	16	platelet	platelet	NN
cord-009417-458rrhcm	42	17	and	and	CC
cord-009417-458rrhcm	42	18	granulocyte	granulocyte	NN
cord-009417-458rrhcm	42	19	function	function	NN
cord-009417-458rrhcm	42	20	is	be	VBZ
cord-009417-458rrhcm	42	21	lost	lose	VBN
cord-009417-458rrhcm	42	22	.	.	.
cord-009417-458rrhcm	43	1	With	with	IN
cord-009417-458rrhcm	43	2	further	further	JJ
cord-009417-458rrhcm	43	3	storage	storage	NN
cord-009417-458rrhcm	43	4	,	,	,
cord-009417-458rrhcm	43	5	levels	level	NNS
cord-009417-458rrhcm	43	6	of	of	IN
cord-009417-458rrhcm	43	7	the	the	DT
cord-009417-458rrhcm	43	8	"	"	``
cord-009417-458rrhcm	43	9	labile	labile	JJ
cord-009417-458rrhcm	43	10	"	"	''
cord-009417-458rrhcm	43	11	coagulation	coagulation	NN
cord-009417-458rrhcm	43	12	factors	factor	NNS
cord-009417-458rrhcm	43	13	V	v	NN
cord-009417-458rrhcm	43	14	and	and	CC
cord-009417-458rrhcm	43	15	VIII	VIII	NNP
cord-009417-458rrhcm	43	16	decrease	decrease	NN
cord-009417-458rrhcm	43	17	.	.	.
cord-009417-458rrhcm	44	1	7	7	CD
cord-009417-458rrhcm	45	1	Some	some	DT
cord-009417-458rrhcm	45	2	blood	blood	NN
cord-009417-458rrhcm	45	3	centers	center	NNS
cord-009417-458rrhcm	45	4	offer	offer	VBP
cord-009417-458rrhcm	45	5	modifi	modifi	RB
cord-009417-458rrhcm	45	6	ed	ed	NNP
cord-009417-458rrhcm	45	7	WB	WB	NNP
cord-009417-458rrhcm	45	8	,	,	,
cord-009417-458rrhcm	45	9	which	which	WDT
cord-009417-458rrhcm	45	10	is	be	VBZ
cord-009417-458rrhcm	45	11	produced	produce	VBN
cord-009417-458rrhcm	45	12	by	by	IN
cord-009417-458rrhcm	45	13	removal	removal	NN
cord-009417-458rrhcm	45	14	of	of	IN
cord-009417-458rrhcm	45	15	the	the	DT
cord-009417-458rrhcm	45	16	platelet	platelet	NN
cord-009417-458rrhcm	45	17	or	or	CC
cord-009417-458rrhcm	45	18	cryoprecipitate	cryoprecipitate	JJ
cord-009417-458rrhcm	45	19	fraction	fraction	NN
cord-009417-458rrhcm	45	20	and	and	CC
cord-009417-458rrhcm	45	21	return	return	NN
cord-009417-458rrhcm	45	22	of	of	IN
cord-009417-458rrhcm	45	23	the	the	DT
cord-009417-458rrhcm	45	24	supernatant	supernatant	JJ
cord-009417-458rrhcm	45	25	plasma	plasma	NN
cord-009417-458rrhcm	45	26	to	to	IN
cord-009417-458rrhcm	45	27	the	the	DT
cord-009417-458rrhcm	45	28	red	red	JJ
cord-009417-458rrhcm	45	29	cells	cell	NNS
cord-009417-458rrhcm	45	30	.	.	.
cord-009417-458rrhcm	46	1	This	this	DT
cord-009417-458rrhcm	46	2	permits	permit	VBZ
cord-009417-458rrhcm	46	3	provision	provision	NN
cord-009417-458rrhcm	46	4	of	of	IN
cord-009417-458rrhcm	46	5	the	the	DT
cord-009417-458rrhcm	46	6	more	more	RBR
cord-009417-458rrhcm	46	7	labile	labile	JJ
cord-009417-458rrhcm	46	8	components	component	NNS
cord-009417-458rrhcm	46	9	to	to	IN
cord-009417-458rrhcm	46	10	patients	patient	NNS
cord-009417-458rrhcm	46	11	with	with	IN
cord-009417-458rrhcm	46	12	specifi	specifi	NNP
cord-009417-458rrhcm	46	13	c	c	NN
cord-009417-458rrhcm	46	14	needs	need	NNS
cord-009417-458rrhcm	46	15	,	,	,
cord-009417-458rrhcm	46	16	with	with	IN
cord-009417-458rrhcm	46	17	the	the	DT
cord-009417-458rrhcm	46	18	remainder	remainder	NN
cord-009417-458rrhcm	46	19	forming	form	VBG
cord-009417-458rrhcm	46	20	a	a	DT
cord-009417-458rrhcm	46	21	product	product	NN
cord-009417-458rrhcm	46	22	having	have	VBG
cord-009417-458rrhcm	46	23	a	a	DT
cord-009417-458rrhcm	46	24	composition	composition	NN
cord-009417-458rrhcm	46	25	essentially	essentially	RB
cord-009417-458rrhcm	46	26	the	the	DT
cord-009417-458rrhcm	46	27	same	same	JJ
cord-009417-458rrhcm	46	28	as	as	IN
cord-009417-458rrhcm	46	29	cold	cold	RB
cord-009417-458rrhcm	46	30	-	-	HYPH
cord-009417-458rrhcm	46	31	stored	store	VBN
cord-009417-458rrhcm	46	32	WB	WB	NNP
cord-009417-458rrhcm	46	33	.	.	.
cord-009417-458rrhcm	47	1	However	however	RB
cord-009417-458rrhcm	47	2	,	,	,
cord-009417-458rrhcm	47	3	the	the	DT
cord-009417-458rrhcm	47	4	growing	grow	VBG
cord-009417-458rrhcm	47	5	need	need	NN
cord-009417-458rrhcm	47	6	for	for	IN
cord-009417-458rrhcm	47	7	specialized	specialized	JJ
cord-009417-458rrhcm	47	8	blood	blood	NN
cord-009417-458rrhcm	47	9	components	component	NNS
cord-009417-458rrhcm	47	10	has	have	VBZ
cord-009417-458rrhcm	47	11	resulted	result	VBN
cord-009417-458rrhcm	47	12	in	in	IN
cord-009417-458rrhcm	47	13	processing	process	VBG
cord-009417-458rrhcm	47	14	the	the	DT
cord-009417-458rrhcm	47	15	majority	majority	NN
cord-009417-458rrhcm	47	16	of	of	IN
cord-009417-458rrhcm	47	17	blood	blood	NN
cord-009417-458rrhcm	47	18	donations	donation	NNS
cord-009417-458rrhcm	47	19	into	into	IN
cord-009417-458rrhcm	47	20	components	component	NNS
cord-009417-458rrhcm	47	21	,	,	,
cord-009417-458rrhcm	47	22	thus	thus	RB
cord-009417-458rrhcm	47	23	limiting	limit	VBG
cord-009417-458rrhcm	47	24	the	the	DT
cord-009417-458rrhcm	47	25	availability	availability	NN
cord-009417-458rrhcm	47	26	of	of	IN
cord-009417-458rrhcm	47	27	WB	WB	NNP
cord-009417-458rrhcm	47	28	and	and	CC
cord-009417-458rrhcm	47	29	modifi	modifi	NNP
cord-009417-458rrhcm	47	30	ed	ed	NNP
cord-009417-458rrhcm	47	31	WB	WB	NNP
cord-009417-458rrhcm	47	32	.	.	.
cord-009417-458rrhcm	48	1	RBCs	rbc	NNS
cord-009417-458rrhcm	48	2	,	,	,
cord-009417-458rrhcm	48	3	or	or	CC
cord-009417-458rrhcm	48	4	in	in	IN
cord-009417-458rrhcm	48	5	common	common	JJ
cord-009417-458rrhcm	48	6	usage	usage	NN
cord-009417-458rrhcm	48	7	,	,	,
cord-009417-458rrhcm	48	8	"	"	``
cord-009417-458rrhcm	48	9	packed	packed	JJ
cord-009417-458rrhcm	48	10	"	"	''
cord-009417-458rrhcm	48	11	red	red	JJ
cord-009417-458rrhcm	48	12	cells	cell	NNS
cord-009417-458rrhcm	48	13	(	(	-LRB-
cord-009417-458rrhcm	48	14	PRBCs	prbc	NNS
cord-009417-458rrhcm	48	15	)	)	-RRB-
cord-009417-458rrhcm	48	16	,	,	,
cord-009417-458rrhcm	48	17	are	be	VBP
cord-009417-458rrhcm	48	18	the	the	DT
cord-009417-458rrhcm	48	19	blood	blood	NN
cord-009417-458rrhcm	48	20	component	component	NN
cord-009417-458rrhcm	48	21	most	most	RBS
cord-009417-458rrhcm	48	22	commonly	commonly	RB
cord-009417-458rrhcm	48	23	transfused	transfuse	VBN
cord-009417-458rrhcm	48	24	to	to	TO
cord-009417-458rrhcm	48	25	increase	increase	VB
cord-009417-458rrhcm	48	26	red	red	JJ
cord-009417-458rrhcm	48	27	cell	cell	NN
cord-009417-458rrhcm	48	28	mass	mass	NN
cord-009417-458rrhcm	48	29	.	.	.
cord-009417-458rrhcm	49	1	PRBCs	prbc	NNS
cord-009417-458rrhcm	49	2	are	be	VBP
cord-009417-458rrhcm	49	3	derived	derive	VBN
cord-009417-458rrhcm	49	4	from	from	IN
cord-009417-458rrhcm	49	5	the	the	DT
cord-009417-458rrhcm	49	6	centrifugation	centrifugation	NN
cord-009417-458rrhcm	49	7	or	or	CC
cord-009417-458rrhcm	49	8	sedimentation	sedimentation	NN
cord-009417-458rrhcm	49	9	of	of	IN
cord-009417-458rrhcm	49	10	WB	WB	NNP
cord-009417-458rrhcm	49	11	and	and	CC
cord-009417-458rrhcm	49	12	removal	removal	NN
cord-009417-458rrhcm	49	13	of	of	IN
cord-009417-458rrhcm	49	14	most	most	JJS
cord-009417-458rrhcm	49	15	of	of	IN
cord-009417-458rrhcm	49	16	the	the	DT
cord-009417-458rrhcm	49	17	plasma	plasma	NN
cord-009417-458rrhcm	49	18	/	/	SYM
cord-009417-458rrhcm	49	19	anticoagulant	anticoagulant	NN
cord-009417-458rrhcm	49	20	solution	solution	NN
cord-009417-458rrhcm	49	21	.	.	.
cord-009417-458rrhcm	50	1	If	if	IN
cord-009417-458rrhcm	50	2	collected	collect	VBN
cord-009417-458rrhcm	50	3	into	into	IN
cord-009417-458rrhcm	50	4	citrate	citrate	NN
cord-009417-458rrhcm	50	5	-	-	HYPH
cord-009417-458rrhcm	50	6	phosphate	phosphate	NN
cord-009417-458rrhcm	50	7	-	-	HYPH
cord-009417-458rrhcm	50	8	dextrose	dextrose	NN
cord-009417-458rrhcm	50	9	-	-	HYPH
cord-009417-458rrhcm	50	10	adenine	adenine	NN
cord-009417-458rrhcm	50	11	solution	solution	NN
cord-009417-458rrhcm	50	12	,	,	,
cord-009417-458rrhcm	50	13	the	the	DT
cord-009417-458rrhcm	50	14	volume	volume	NN
cord-009417-458rrhcm	50	15	is	be	VBZ
cord-009417-458rrhcm	50	16	approximately	approximately	RB
cord-009417-458rrhcm	50	17	250	250	CD
cord-009417-458rrhcm	50	18	mL	ml	NN
cord-009417-458rrhcm	50	19	,	,	,
cord-009417-458rrhcm	50	20	the	the	DT
cord-009417-458rrhcm	50	21	hematocrit	hematocrit	NN
cord-009417-458rrhcm	50	22	(	(	-LRB-
cord-009417-458rrhcm	50	23	Hct	Hct	NNP
cord-009417-458rrhcm	50	24	)	)	-RRB-
cord-009417-458rrhcm	50	25	is	be	VBZ
cord-009417-458rrhcm	50	26	70	70	CD
cord-009417-458rrhcm	50	27	%	%	NN
cord-009417-458rrhcm	50	28	to	to	TO
cord-009417-458rrhcm	50	29	80	80	CD
cord-009417-458rrhcm	50	30	%	%	NN
cord-009417-458rrhcm	50	31	,	,	,
cord-009417-458rrhcm	50	32	and	and	CC
cord-009417-458rrhcm	50	33	the	the	DT
cord-009417-458rrhcm	50	34	storage	storage	NN
cord-009417-458rrhcm	50	35	life	life	NN
cord-009417-458rrhcm	50	36	is	be	VBZ
cord-009417-458rrhcm	50	37	35	35	CD
cord-009417-458rrhcm	50	38	days	day	NNS
cord-009417-458rrhcm	50	39	.	.	.
cord-009417-458rrhcm	51	1	Extended	extended	JJ
cord-009417-458rrhcm	51	2	additive	additive	NN
cord-009417-458rrhcm	51	3	solutions	solution	NNS
cord-009417-458rrhcm	51	4	permit	permit	NN
cord-009417-458rrhcm	51	5	storage	storage	NN
cord-009417-458rrhcm	51	6	up	up	IN
cord-009417-458rrhcm	51	7	to	to	TO
cord-009417-458rrhcm	51	8	42	42	CD
cord-009417-458rrhcm	51	9	days	day	NNS
cord-009417-458rrhcm	51	10	but	but	CC
cord-009417-458rrhcm	51	11	increase	increase	VB
cord-009417-458rrhcm	51	12	the	the	DT
cord-009417-458rrhcm	51	13	volume	volume	NN
cord-009417-458rrhcm	51	14	to	to	IN
cord-009417-458rrhcm	51	15	300	300	CD
cord-009417-458rrhcm	51	16	mL	ml	NN
cord-009417-458rrhcm	51	17	and	and	CC
cord-009417-458rrhcm	51	18	decrease	decrease	VB
cord-009417-458rrhcm	51	19	the	the	DT
cord-009417-458rrhcm	51	20	Hct	Hct	NNP
cord-009417-458rrhcm	51	21	to	to	TO
cord-009417-458rrhcm	51	22	60	60	CD
cord-009417-458rrhcm	51	23	%	%	NN
cord-009417-458rrhcm	51	24	.	.	.
cord-009417-458rrhcm	52	1	These	these	DT
cord-009417-458rrhcm	52	2	extended	extend	VBN
cord-009417-458rrhcm	52	3	storage	storage	NN
cord-009417-458rrhcm	52	4	units	unit	NNS
cord-009417-458rrhcm	52	5	are	be	VBP
cord-009417-458rrhcm	52	6	commonly	commonly	RB
cord-009417-458rrhcm	52	7	used	use	VBN
cord-009417-458rrhcm	52	8	and	and	CC
cord-009417-458rrhcm	52	9	easier	easy	JJR
cord-009417-458rrhcm	52	10	to	to	TO
cord-009417-458rrhcm	52	11	transfuse	transfuse	VB
cord-009417-458rrhcm	52	12	because	because	IN
cord-009417-458rrhcm	52	13	of	of	IN
cord-009417-458rrhcm	52	14	lower	low	JJR
cord-009417-458rrhcm	52	15	viscosity	viscosity	NN
cord-009417-458rrhcm	52	16	,	,	,
cord-009417-458rrhcm	52	17	but	but	CC
cord-009417-458rrhcm	52	18	they	-PRON-	PRP
cord-009417-458rrhcm	52	19	may	may	MD
cord-009417-458rrhcm	52	20	pose	pose	VB
cord-009417-458rrhcm	52	21	a	a	DT
cord-009417-458rrhcm	52	22	problem	problem	NN
cord-009417-458rrhcm	52	23	because	because	IN
cord-009417-458rrhcm	52	24	of	of	IN
cord-009417-458rrhcm	52	25	their	-PRON-	PRP$
cord-009417-458rrhcm	52	26	larger	large	JJR
cord-009417-458rrhcm	52	27	volume	volume	NN
cord-009417-458rrhcm	52	28	.	.	.
cord-009417-458rrhcm	53	1	The	the	DT
cord-009417-458rrhcm	53	2	transfusion	transfusion	NN
cord-009417-458rrhcm	53	3	of	of	IN
cord-009417-458rrhcm	53	4	leukocyte	leukocyte	NN
cord-009417-458rrhcm	53	5	-	-	HYPH
cord-009417-458rrhcm	53	6	reduced	reduce	VBN
cord-009417-458rrhcm	53	7	RBCs	rbc	NNS
cord-009417-458rrhcm	53	8	may	may	MD
cord-009417-458rrhcm	53	9	benefi	benefi	VB
cord-009417-458rrhcm	53	10	t	t	NNP
cord-009417-458rrhcm	53	11	certain	certain	JJ
cord-009417-458rrhcm	53	12	patients	patient	NNS
cord-009417-458rrhcm	53	13	.	.	.
cord-009417-458rrhcm	54	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	54	2	of	of	IN
cord-009417-458rrhcm	54	3	blood	blood	NN
cord-009417-458rrhcm	54	4	components	component	NNS
cord-009417-458rrhcm	54	5	containing	contain	VBG
cord-009417-458rrhcm	54	6	leukocytes	leukocyte	NNS
cord-009417-458rrhcm	54	7	may	may	MD
cord-009417-458rrhcm	54	8	lead	lead	VB
cord-009417-458rrhcm	54	9	to	to	IN
cord-009417-458rrhcm	54	10	febrile	febrile	JJ
cord-009417-458rrhcm	54	11	reactions	reaction	NNS
cord-009417-458rrhcm	54	12	,	,	,
cord-009417-458rrhcm	54	13	a	a	DT
cord-009417-458rrhcm	54	14	greater	great	JJR
cord-009417-458rrhcm	54	15	propensity	propensity	NN
cord-009417-458rrhcm	54	16	for	for	IN
cord-009417-458rrhcm	54	17	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	54	18	,	,	,
cord-009417-458rrhcm	54	19	platelet	platelet	NN
cord-009417-458rrhcm	54	20	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	54	21	,	,	,
cord-009417-458rrhcm	54	22	and	and	CC
cord-009417-458rrhcm	54	23	transmission	transmission	NN
cord-009417-458rrhcm	54	24	of	of	IN
cord-009417-458rrhcm	54	25	pathogens	pathogen	NNS
cord-009417-458rrhcm	54	26	carried	carry	VBN
cord-009417-458rrhcm	54	27	by	by	IN
cord-009417-458rrhcm	54	28	leukocytes	leukocyte	NNS
cord-009417-458rrhcm	54	29	,	,	,
cord-009417-458rrhcm	54	30	such	such	JJ
cord-009417-458rrhcm	54	31	as	as	IN
cord-009417-458rrhcm	54	32	cytomegalovirus	cytomegalovirus	NNP
cord-009417-458rrhcm	54	33	(	(	-LRB-
cord-009417-458rrhcm	54	34	CMV	CMV	NNP
cord-009417-458rrhcm	54	35	)	)	-RRB-
cord-009417-458rrhcm	54	36	.	.	.
cord-009417-458rrhcm	55	1	Leukocyte	Leukocyte	NNP
cord-009417-458rrhcm	55	2	reduction	reduction	NN
cord-009417-458rrhcm	55	3	,	,	,
cord-009417-458rrhcm	55	4	as	as	IN
cord-009417-458rrhcm	55	5	defi	defi	NNP
cord-009417-458rrhcm	55	6	ned	ned	NNP
cord-009417-458rrhcm	55	7	by	by	IN
cord-009417-458rrhcm	55	8	the	the	DT
cord-009417-458rrhcm	55	9	FDA	FDA	NNP
cord-009417-458rrhcm	55	10	,	,	,
cord-009417-458rrhcm	55	11	requires	require	VBZ
cord-009417-458rrhcm	55	12	fi	fi	IN
cord-009417-458rrhcm	55	13	ltration	ltration	NN
cord-009417-458rrhcm	55	14	of	of	IN
cord-009417-458rrhcm	55	15	the	the	DT
cord-009417-458rrhcm	55	16	blood	blood	NN
cord-009417-458rrhcm	55	17	component	component	NN
cord-009417-458rrhcm	55	18	by	by	IN
cord-009417-458rrhcm	55	19	a	a	DT
cord-009417-458rrhcm	55	20	special	special	JJ
cord-009417-458rrhcm	55	21	fi	fi	NN
cord-009417-458rrhcm	55	22	lter	lter	NN
cord-009417-458rrhcm	55	23	.	.	.
cord-009417-458rrhcm	56	1	1	1	CD
cord-009417-458rrhcm	56	2	Filtration	Filtration	NNP
cord-009417-458rrhcm	56	3	may	may	MD
cord-009417-458rrhcm	56	4	be	be	VB
cord-009417-458rrhcm	56	5	performed	perform	VBN
cord-009417-458rrhcm	56	6	either	either	CC
cord-009417-458rrhcm	56	7	at	at	IN
cord-009417-458rrhcm	56	8	the	the	DT
cord-009417-458rrhcm	56	9	time	time	NN
cord-009417-458rrhcm	56	10	of	of	IN
cord-009417-458rrhcm	56	11	blood	blood	NN
cord-009417-458rrhcm	56	12	donation	donation	NN
cord-009417-458rrhcm	56	13	and	and	CC
cord-009417-458rrhcm	56	14	processing	processing	NN
cord-009417-458rrhcm	56	15	or	or	CC
cord-009417-458rrhcm	56	16	later	later	RB
cord-009417-458rrhcm	56	17	at	at	IN
cord-009417-458rrhcm	56	18	the	the	DT
cord-009417-458rrhcm	56	19	time	time	NN
cord-009417-458rrhcm	56	20	of	of	IN
cord-009417-458rrhcm	56	21	transfusion	transfusion	NN
cord-009417-458rrhcm	56	22	(	(	-LRB-
cord-009417-458rrhcm	56	23	"	"	``
cord-009417-458rrhcm	56	24	bedside	bedside	NN
cord-009417-458rrhcm	56	25	fi	fi	NN
cord-009417-458rrhcm	56	26	ltration	ltration	NN
cord-009417-458rrhcm	56	27	"	"	''
cord-009417-458rrhcm	56	28	)	)	-RRB-
cord-009417-458rrhcm	56	29	.	.	.
cord-009417-458rrhcm	57	1	Filtration	filtration	NN
cord-009417-458rrhcm	57	2	before	before	IN
cord-009417-458rrhcm	57	3	storage	storage	NN
cord-009417-458rrhcm	57	4	conveys	convey	VBZ
cord-009417-458rrhcm	57	5	the	the	DT
cord-009417-458rrhcm	57	6	benefi	benefi	NNP
cord-009417-458rrhcm	57	7	t	t	NN
cord-009417-458rrhcm	57	8	of	of	IN
cord-009417-458rrhcm	57	9	removing	remove	VBG
cord-009417-458rrhcm	57	10	white	white	JJ
cord-009417-458rrhcm	57	11	blood	blood	NN
cord-009417-458rrhcm	57	12	cells	cell	NNS
cord-009417-458rrhcm	57	13	(	(	-LRB-
cord-009417-458rrhcm	57	14	WBCs	wbc	NNS
cord-009417-458rrhcm	57	15	)	)	-RRB-
cord-009417-458rrhcm	57	16	before	before	IN
cord-009417-458rrhcm	57	17	they	-PRON-	PRP
cord-009417-458rrhcm	57	18	can	can	MD
cord-009417-458rrhcm	57	19	deteriorate	deteriorate	VB
cord-009417-458rrhcm	57	20	and	and	CC
cord-009417-458rrhcm	57	21	elaborate	elaborate	VB
cord-009417-458rrhcm	57	22	cytokines	cytokine	NNS
cord-009417-458rrhcm	57	23	and	and	CC
cord-009417-458rrhcm	57	24	other	other	JJ
cord-009417-458rrhcm	57	25	unwanted	unwanted	JJ
cord-009417-458rrhcm	57	26	substances	substance	NNS
cord-009417-458rrhcm	57	27	during	during	IN
cord-009417-458rrhcm	57	28	storage	storage	NN
cord-009417-458rrhcm	57	29	.	.	.
cord-009417-458rrhcm	58	1	8	8	CD
cord-009417-458rrhcm	59	1	Because	because	IN
cord-009417-458rrhcm	59	2	of	of	IN
cord-009417-458rrhcm	59	3	proven	prove	VBN
cord-009417-458rrhcm	59	4	and	and	CC
cord-009417-458rrhcm	59	5	theoretical	theoretical	JJ
cord-009417-458rrhcm	59	6	benefi	benefi	JJ
cord-009417-458rrhcm	59	7	ts	ts	NN
cord-009417-458rrhcm	59	8	of	of	IN
cord-009417-458rrhcm	59	9	leukocyte	leukocyte	NN
cord-009417-458rrhcm	59	10	reduction	reduction	NN
cord-009417-458rrhcm	59	11	of	of	IN
cord-009417-458rrhcm	59	12	blood	blood	NN
cord-009417-458rrhcm	59	13	components	component	NNS
cord-009417-458rrhcm	59	14	(	(	-LRB-
cord-009417-458rrhcm	59	15	discussed	discuss	VBN
cord-009417-458rrhcm	59	16	later	later	RB
cord-009417-458rrhcm	59	17	in	in	IN
cord-009417-458rrhcm	59	18	the	the	DT
cord-009417-458rrhcm	59	19	section	section	NN
cord-009417-458rrhcm	59	20	covering	cover	VBG
cord-009417-458rrhcm	59	21	the	the	DT
cord-009417-458rrhcm	59	22	adverse	adverse	JJ
cord-009417-458rrhcm	59	23	effects	effect	NNS
cord-009417-458rrhcm	59	24	of	of	IN
cord-009417-458rrhcm	59	25	transfusion	transfusion	NN
cord-009417-458rrhcm	59	26	)	)	-RRB-
cord-009417-458rrhcm	59	27	,	,	,
cord-009417-458rrhcm	59	28	many	many	JJ
cord-009417-458rrhcm	59	29	European	european	JJ
cord-009417-458rrhcm	59	30	countries	country	NNS
cord-009417-458rrhcm	59	31	and	and	CC
cord-009417-458rrhcm	59	32	Canada	Canada	NNP
cord-009417-458rrhcm	59	33	require	require	VBP
cord-009417-458rrhcm	59	34	that	that	IN
cord-009417-458rrhcm	59	35	all	all	DT
cord-009417-458rrhcm	59	36	transfusions	transfusion	NNS
cord-009417-458rrhcm	59	37	be	be	VBP
cord-009417-458rrhcm	59	38	leukocyte	leukocyte	NN
cord-009417-458rrhcm	59	39	reduced	reduce	VBN
cord-009417-458rrhcm	59	40	,	,	,
cord-009417-458rrhcm	59	41	a	a	DT
cord-009417-458rrhcm	59	42	process	process	NN
cord-009417-458rrhcm	59	43	called	call	VBN
cord-009417-458rrhcm	59	44	universal	universal	JJ
cord-009417-458rrhcm	59	45	leukoreduction	leukoreduction	NN
cord-009417-458rrhcm	59	46	(	(	-LRB-
cord-009417-458rrhcm	59	47	ULR	ULR	NNP
cord-009417-458rrhcm	59	48	)	)	-RRB-
cord-009417-458rrhcm	59	49	.	.	.
cord-009417-458rrhcm	60	1	Some	some	DT
cord-009417-458rrhcm	60	2	institutions	institution	NNS
cord-009417-458rrhcm	60	3	in	in	IN
cord-009417-458rrhcm	60	4	the	the	DT
cord-009417-458rrhcm	60	5	United	United	NNP
cord-009417-458rrhcm	60	6	States	States	NNP
cord-009417-458rrhcm	60	7	have	have	VBP
cord-009417-458rrhcm	60	8	also	also	RB
cord-009417-458rrhcm	60	9	made	make	VBN
cord-009417-458rrhcm	60	10	that	that	DT
cord-009417-458rrhcm	60	11	decision	decision	NN
cord-009417-458rrhcm	60	12	,	,	,
cord-009417-458rrhcm	60	13	but	but	CC
cord-009417-458rrhcm	60	14	either	either	DT
cord-009417-458rrhcm	60	15	method	method	NN
cord-009417-458rrhcm	60	16	of	of	IN
cord-009417-458rrhcm	60	17	leukocyte	leukocyte	NN
cord-009417-458rrhcm	60	18	reduction	reduction	NN
cord-009417-458rrhcm	60	19	adds	add	VBZ
cord-009417-458rrhcm	60	20	signifi	signifi	NNP
cord-009417-458rrhcm	60	21	cantly	cantly	RB
cord-009417-458rrhcm	60	22	to	to	IN
cord-009417-458rrhcm	60	23	the	the	DT
cord-009417-458rrhcm	60	24	cost	cost	NN
cord-009417-458rrhcm	60	25	of	of	IN
cord-009417-458rrhcm	60	26	each	each	DT
cord-009417-458rrhcm	60	27	transfusion	transfusion	NN
cord-009417-458rrhcm	60	28	(	(	-LRB-
cord-009417-458rrhcm	60	29	$	$	$
cord-009417-458rrhcm	60	30	25	25	CD
cord-009417-458rrhcm	60	31	to	to	TO
cord-009417-458rrhcm	60	32	$	$	$
cord-009417-458rrhcm	60	33	30	30	CD
cord-009417-458rrhcm	60	34	)	)	-RRB-
cord-009417-458rrhcm	60	35	,	,	,
cord-009417-458rrhcm	60	36	and	and	CC
cord-009417-458rrhcm	60	37	the	the	DT
cord-009417-458rrhcm	60	38	benefi	benefi	JJ
cord-009417-458rrhcm	60	39	ts	ts	NN
cord-009417-458rrhcm	60	40	of	of	IN
cord-009417-458rrhcm	60	41	this	this	DT
cord-009417-458rrhcm	60	42	measure	measure	NN
cord-009417-458rrhcm	60	43	when	when	WRB
cord-009417-458rrhcm	60	44	applied	apply	VBN
cord-009417-458rrhcm	60	45	globally	globally	RB
cord-009417-458rrhcm	60	46	have	have	VBP
cord-009417-458rrhcm	60	47	yet	yet	RB
cord-009417-458rrhcm	60	48	to	to	TO
cord-009417-458rrhcm	60	49	be	be	VB
cord-009417-458rrhcm	60	50	quantifi	quantifi	NNP
cord-009417-458rrhcm	60	51	ed	ed	NNP
cord-009417-458rrhcm	60	52	.	.	NNP
cord-009417-458rrhcm	60	53	9	9	CD
cord-009417-458rrhcm	61	1	Washing	washing	NN
cord-009417-458rrhcm	61	2	PRBCs	prbc	NNS
cord-009417-458rrhcm	61	3	involves	involve	VBZ
cord-009417-458rrhcm	61	4	recentrifuging	recentrifuge	VBG
cord-009417-458rrhcm	61	5	to	to	TO
cord-009417-458rrhcm	61	6	remove	remove	VB
cord-009417-458rrhcm	61	7	the	the	DT
cord-009417-458rrhcm	61	8	plasma	plasma	NN
cord-009417-458rrhcm	61	9	/	/	SYM
cord-009417-458rrhcm	61	10	preservative	preservative	NN
cord-009417-458rrhcm	61	11	solution	solution	NN
cord-009417-458rrhcm	61	12	from	from	IN
cord-009417-458rrhcm	61	13	the	the	DT
cord-009417-458rrhcm	61	14	unit	unit	NN
cord-009417-458rrhcm	61	15	.	.	.
cord-009417-458rrhcm	62	1	However	however	RB
cord-009417-458rrhcm	62	2	,	,	,
cord-009417-458rrhcm	62	3	washing	washing	NN
cord-009417-458rrhcm	62	4	may	may	MD
cord-009417-458rrhcm	62	5	take	take	VB
cord-009417-458rrhcm	62	6	an	an	DT
cord-009417-458rrhcm	62	7	hour	hour	NN
cord-009417-458rrhcm	62	8	or	or	CC
cord-009417-458rrhcm	62	9	more	more	JJR
cord-009417-458rrhcm	62	10	,	,	,
cord-009417-458rrhcm	62	11	limits	limit	VBZ
cord-009417-458rrhcm	62	12	subsequent	subsequent	JJ
cord-009417-458rrhcm	62	13	storage	storage	NN
cord-009417-458rrhcm	62	14	time	time	NN
cord-009417-458rrhcm	62	15	,	,	,
cord-009417-458rrhcm	62	16	and	and	CC
cord-009417-458rrhcm	62	17	causes	cause	VBZ
cord-009417-458rrhcm	62	18	some	some	DT
cord-009417-458rrhcm	62	19	loss	loss	NN
cord-009417-458rrhcm	62	20	of	of	IN
cord-009417-458rrhcm	62	21	RBCs	rbc	NNS
cord-009417-458rrhcm	62	22	.	.	.
cord-009417-458rrhcm	63	1	Washing	washing	NN
cord-009417-458rrhcm	63	2	is	be	VBZ
cord-009417-458rrhcm	63	3	also	also	RB
cord-009417-458rrhcm	63	4	not	not	RB
cord-009417-458rrhcm	63	5	an	an	DT
cord-009417-458rrhcm	63	6	effective	effective	JJ
cord-009417-458rrhcm	63	7	method	method	NN
cord-009417-458rrhcm	63	8	of	of	IN
cord-009417-458rrhcm	63	9	leukoreduction	leukoreduction	NN
cord-009417-458rrhcm	63	10	.	.	.
cord-009417-458rrhcm	64	1	There	there	EX
cord-009417-458rrhcm	64	2	are	be	VBP
cord-009417-458rrhcm	64	3	very	very	RB
cord-009417-458rrhcm	64	4	few	few	JJ
cord-009417-458rrhcm	64	5	indications	indication	NNS
cord-009417-458rrhcm	64	6	for	for	IN
cord-009417-458rrhcm	64	7	the	the	DT
cord-009417-458rrhcm	64	8	use	use	NN
cord-009417-458rrhcm	64	9	of	of	IN
cord-009417-458rrhcm	64	10	washed	washed	JJ
cord-009417-458rrhcm	64	11	RBCs	rbc	NNS
cord-009417-458rrhcm	64	12	,	,	,
cord-009417-458rrhcm	64	13	although	although	IN
cord-009417-458rrhcm	64	14	some	some	DT
cord-009417-458rrhcm	64	15	recipients	recipient	NNS
cord-009417-458rrhcm	64	16	with	with	IN
cord-009417-458rrhcm	64	17	plasma	plasma	NN
cord-009417-458rrhcm	64	18	reactions	reaction	NNS
cord-009417-458rrhcm	64	19	may	may	MD
cord-009417-458rrhcm	64	20	benefi	benefi	VB
cord-009417-458rrhcm	64	21	t.	t.	NNP
cord-009417-458rrhcm	64	22	PRBCs	prbc	NNS
cord-009417-458rrhcm	64	23	can	can	MD
cord-009417-458rrhcm	64	24	be	be	VB
cord-009417-458rrhcm	64	25	frozen	freeze	VBN
cord-009417-458rrhcm	64	26	in	in	IN
cord-009417-458rrhcm	64	27	cryoprotective	cryoprotective	JJ
cord-009417-458rrhcm	64	28	solution	solution	NN
cord-009417-458rrhcm	64	29	and	and	CC
cord-009417-458rrhcm	64	30	stored	store	VBN
cord-009417-458rrhcm	64	31	for	for	IN
cord-009417-458rrhcm	64	32	extended	extended	JJ
cord-009417-458rrhcm	64	33	periods	period	NNS
cord-009417-458rrhcm	64	34	.	.	.
cord-009417-458rrhcm	65	1	Frozen	frozen	JJ
cord-009417-458rrhcm	65	2	RBCs	rbc	NNS
cord-009417-458rrhcm	65	3	are	be	VBP
cord-009417-458rrhcm	65	4	generally	generally	RB
cord-009417-458rrhcm	65	5	limited	limit	VBN
cord-009417-458rrhcm	65	6	to	to	IN
cord-009417-458rrhcm	65	7	units	unit	NNS
cord-009417-458rrhcm	65	8	of	of	IN
cord-009417-458rrhcm	65	9	special	special	JJ
cord-009417-458rrhcm	65	10	value	value	NN
cord-009417-458rrhcm	65	11	,	,	,
cord-009417-458rrhcm	65	12	such	such	JJ
cord-009417-458rrhcm	65	13	as	as	IN
cord-009417-458rrhcm	65	14	those	those	DT
cord-009417-458rrhcm	65	15	with	with	IN
cord-009417-458rrhcm	65	16	a	a	DT
cord-009417-458rrhcm	65	17	rare	rare	JJ
cord-009417-458rrhcm	65	18	RBC	RBC	NNP
cord-009417-458rrhcm	65	19	antigen	antigen	NN
cord-009417-458rrhcm	65	20	profi	profi	NNP
cord-009417-458rrhcm	65	21	le	le	NNP
cord-009417-458rrhcm	65	22	or	or	CC
cord-009417-458rrhcm	65	23	autologous	autologous	JJ
cord-009417-458rrhcm	65	24	blood	blood	NN
cord-009417-458rrhcm	65	25	donations	donation	NNS
cord-009417-458rrhcm	65	26	that	that	WDT
cord-009417-458rrhcm	65	27	need	need	VBP
cord-009417-458rrhcm	65	28	to	to	TO
cord-009417-458rrhcm	65	29	be	be	VB
cord-009417-458rrhcm	65	30	stored	store	VBN
cord-009417-458rrhcm	65	31	for	for	IN
cord-009417-458rrhcm	65	32	future	future	JJ
cord-009417-458rrhcm	65	33	use	use	NN
cord-009417-458rrhcm	65	34	.	.	.
cord-009417-458rrhcm	66	1	A	a	DT
cord-009417-458rrhcm	66	2	rare	rare	JJ
cord-009417-458rrhcm	66	3	-	-	HYPH
cord-009417-458rrhcm	66	4	donor	donor	NN
cord-009417-458rrhcm	66	5	registry	registry	NN
cord-009417-458rrhcm	66	6	of	of	IN
cord-009417-458rrhcm	66	7	frozen	frozen	JJ
cord-009417-458rrhcm	66	8	PRBCs	prbc	NNS
cord-009417-458rrhcm	66	9	exists	exist	VBZ
cord-009417-458rrhcm	66	10	to	to	TO
cord-009417-458rrhcm	66	11	assist	assist	VB
cord-009417-458rrhcm	66	12	in	in	IN
cord-009417-458rrhcm	66	13	providing	provide	VBG
cord-009417-458rrhcm	66	14	blood	blood	NN
cord-009417-458rrhcm	66	15	to	to	IN
cord-009417-458rrhcm	66	16	patients	patient	NNS
cord-009417-458rrhcm	66	17	with	with	IN
cord-009417-458rrhcm	66	18	complex	complex	JJ
cord-009417-458rrhcm	66	19	or	or	CC
cord-009417-458rrhcm	66	20	multiple	multiple	JJ
cord-009417-458rrhcm	66	21	alloantibodies	alloantibody	NNS
cord-009417-458rrhcm	66	22	to	to	IN
cord-009417-458rrhcm	66	23	red	red	JJ
cord-009417-458rrhcm	66	24	cell	cell	NN
cord-009417-458rrhcm	66	25	antigens	antigen	NNS
cord-009417-458rrhcm	66	26	.	.	.
cord-009417-458rrhcm	67	1	Signifi	Signifi	NNP
cord-009417-458rrhcm	67	2	ca	can	MD
cord-009417-458rrhcm	67	3	nt	not	RB
cord-009417-458rrhcm	67	4	advanced	advanced	JJ
cord-009417-458rrhcm	67	5	planning	planning	NN
cord-009417-458rrhcm	67	6	is	be	VBZ
cord-009417-458rrhcm	67	7	necessary	necessary	JJ
cord-009417-458rrhcm	67	8	to	to	TO
cord-009417-458rrhcm	67	9	acquire	acquire	VB
cord-009417-458rrhcm	67	10	and	and	CC
cord-009417-458rrhcm	67	11	thaw	thaw	VB
cord-009417-458rrhcm	67	12	frozen	frozen	JJ
cord-009417-458rrhcm	67	13	PRBCs	prbc	NNS
cord-009417-458rrhcm	67	14	for	for	IN
cord-009417-458rrhcm	67	15	transfusion	transfusion	NN
cord-009417-458rrhcm	67	16	,	,	,
cord-009417-458rrhcm	67	17	thus	thus	RB
cord-009417-458rrhcm	67	18	limiting	limit	VBG
cord-009417-458rrhcm	67	19	their	-PRON-	PRP$
cord-009417-458rrhcm	67	20	use	use	NN
cord-009417-458rrhcm	67	21	in	in	IN
cord-009417-458rrhcm	67	22	acute	acute	JJ
cord-009417-458rrhcm	67	23	situations	situation	NNS
cord-009417-458rrhcm	67	24	.	.	.
cord-009417-458rrhcm	68	1	WB	WB	NNP
cord-009417-458rrhcm	68	2	and	and	CC
cord-009417-458rrhcm	68	3	PRBCs	prbc	NNS
cord-009417-458rrhcm	68	4	suffer	suffer	VBP
cord-009417-458rrhcm	68	5	some	some	DT
cord-009417-458rrhcm	68	6	cell	cell	NN
cord-009417-458rrhcm	68	7	loss	loss	NN
cord-009417-458rrhcm	68	8	during	during	IN
cord-009417-458rrhcm	68	9	storage	storage	NN
cord-009417-458rrhcm	68	10	.	.	.
cord-009417-458rrhcm	69	1	The	the	DT
cord-009417-458rrhcm	69	2	current	current	JJ
cord-009417-458rrhcm	69	3	technology	technology	NN
cord-009417-458rrhcm	69	4	of	of	IN
cord-009417-458rrhcm	69	5	bag	bag	NN
cord-009417-458rrhcm	69	6	and	and	CC
cord-009417-458rrhcm	69	7	preservative	preservative	NN
cord-009417-458rrhcm	69	8	solutions	solution	NNS
cord-009417-458rrhcm	69	9	attempts	attempt	NNS
cord-009417-458rrhcm	69	10	to	to	TO
cord-009417-458rrhcm	69	11	optimize	optimize	VB
cord-009417-458rrhcm	69	12	cell	cell	NN
cord-009417-458rrhcm	69	13	quality	quality	NN
cord-009417-458rrhcm	69	14	and	and	CC
cord-009417-458rrhcm	69	15	quantity	quantity	NN
cord-009417-458rrhcm	69	16	by	by	IN
cord-009417-458rrhcm	69	17	using	use	VBG
cord-009417-458rrhcm	69	18	strict	strict	JJ
cord-009417-458rrhcm	69	19	criteria	criterion	NNS
cord-009417-458rrhcm	69	20	to	to	TO
cord-009417-458rrhcm	69	21	determine	determine	VB
cord-009417-458rrhcm	69	22	the	the	DT
cord-009417-458rrhcm	69	23	length	length	NN
cord-009417-458rrhcm	69	24	of	of	IN
cord-009417-458rrhcm	69	25	allowable	allowable	JJ
cord-009417-458rrhcm	69	26	storage	storage	NN
cord-009417-458rrhcm	69	27	time	time	NN
cord-009417-458rrhcm	69	28	.	.	.
cord-009417-458rrhcm	70	1	Nonetheless	nonetheless	RB
cord-009417-458rrhcm	70	2	,	,	,
cord-009417-458rrhcm	70	3	as	as	IN
cord-009417-458rrhcm	70	4	red	red	JJ
cord-009417-458rrhcm	70	5	cell	cell	NN
cord-009417-458rrhcm	70	6	metabolism	metabolism	NN
cord-009417-458rrhcm	70	7	decreases	decrease	VBZ
cord-009417-458rrhcm	70	8	progressively	progressively	RB
cord-009417-458rrhcm	70	9	,	,	,
cord-009417-458rrhcm	70	10	a	a	DT
cord-009417-458rrhcm	70	11	"	"	``
cord-009417-458rrhcm	70	12	storage	storage	NN
cord-009417-458rrhcm	70	13	lesion	lesion	NN
cord-009417-458rrhcm	70	14	"	"	''
cord-009417-458rrhcm	70	15	results	result	NNS
cord-009417-458rrhcm	70	16	,	,	,
cord-009417-458rrhcm	70	17	10	10	CD
cord-009417-458rrhcm	70	18	with	with	IN
cord-009417-458rrhcm	70	19	accumulation	accumulation	NN
cord-009417-458rrhcm	70	20	of	of	IN
cord-009417-458rrhcm	70	21	a	a	DT
cord-009417-458rrhcm	70	22	variety	variety	NN
cord-009417-458rrhcm	70	23	of	of	IN
cord-009417-458rrhcm	70	24	undesirable	undesirable	JJ
cord-009417-458rrhcm	70	25	substances	substance	NNS
cord-009417-458rrhcm	70	26	and	and	CC
cord-009417-458rrhcm	70	27	loss	loss	NN
cord-009417-458rrhcm	70	28	of	of	IN
cord-009417-458rrhcm	70	29	cellular	cellular	JJ
cord-009417-458rrhcm	70	30	function	function	NN
cord-009417-458rrhcm	70	31	.	.	.
cord-009417-458rrhcm	71	1	Over	over	IN
cord-009417-458rrhcm	71	2	time	time	NN
cord-009417-458rrhcm	71	3	in	in	IN
cord-009417-458rrhcm	71	4	storage	storage	NN
cord-009417-458rrhcm	71	5	,	,	,
cord-009417-458rrhcm	71	6	a	a	DT
cord-009417-458rrhcm	71	7	slow	slow	JJ
cord-009417-458rrhcm	71	8	rise	rise	NN
cord-009417-458rrhcm	71	9	in	in	IN
cord-009417-458rrhcm	71	10	the	the	DT
cord-009417-458rrhcm	71	11	concentration	concentration	NN
cord-009417-458rrhcm	71	12	of	of	IN
cord-009417-458rrhcm	71	13	potassium	potassium	NN
cord-009417-458rrhcm	71	14	,	,	,
cord-009417-458rrhcm	71	15	lactate	lactate	NN
cord-009417-458rrhcm	71	16	,	,	,
cord-009417-458rrhcm	71	17	aspartate	aspartate	NN
cord-009417-458rrhcm	71	18	aminotransferase	aminotransferase	NN
cord-009417-458rrhcm	71	19	,	,	,
cord-009417-458rrhcm	71	20	lactate	lactate	NN
cord-009417-458rrhcm	71	21	dehydrogenase	dehydrogenase	NN
cord-009417-458rrhcm	71	22	,	,	,
cord-009417-458rrhcm	71	23	ammonia	ammonia	NN
cord-009417-458rrhcm	71	24	,	,	,
cord-009417-458rrhcm	71	25	phosphate	phosphate	NN
cord-009417-458rrhcm	71	26	,	,	,
cord-009417-458rrhcm	71	27	and	and	CC
cord-009417-458rrhcm	71	28	free	free	JJ
cord-009417-458rrhcm	71	29	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	71	30	and	and	CC
cord-009417-458rrhcm	71	31	a	a	DT
cord-009417-458rrhcm	71	32	slow	slow	JJ
cord-009417-458rrhcm	71	33	decrease	decrease	NN
cord-009417-458rrhcm	71	34	in	in	IN
cord-009417-458rrhcm	71	35	pH	ph	NN
cord-009417-458rrhcm	71	36	and	and	CC
cord-009417-458rrhcm	71	37	bicarbonate	bicarbonate	NN
cord-009417-458rrhcm	71	38	concentration	concentration	NN
cord-009417-458rrhcm	71	39	occur	occur	VBP
cord-009417-458rrhcm	71	40	.	.	.
cord-009417-458rrhcm	72	1	Cytokines	cytokine	NNS
cord-009417-458rrhcm	72	2	and	and	CC
cord-009417-458rrhcm	72	3	infl	infl	NNP
cord-009417-458rrhcm	72	4	ammatory	ammatory	NNP
cord-009417-458rrhcm	72	5	mediators	mediator	NNS
cord-009417-458rrhcm	72	6	such	such	JJ
cord-009417-458rrhcm	72	7	as	as	IN
cord-009417-458rrhcm	72	8	interleukin-1	interleukin-1	NN
cord-009417-458rrhcm	72	9	,	,	,
cord-009417-458rrhcm	72	10	interleukin-6	interleukin-6	NN
cord-009417-458rrhcm	72	11	and	and	CC
cord-009417-458rrhcm	72	12	tumor	tumor	NN
cord-009417-458rrhcm	72	13	necrosis	necrosis	NN
cord-009417-458rrhcm	72	14	factor	factor	NN
cord-009417-458rrhcm	72	15	also	also	RB
cord-009417-458rrhcm	72	16	accumulate	accumulate	VBP
cord-009417-458rrhcm	72	17	.	.	.
cord-009417-458rrhcm	73	1	The	the	DT
cord-009417-458rrhcm	73	2	pH	ph	NN
cord-009417-458rrhcm	73	3	of	of	IN
cord-009417-458rrhcm	73	4	freshly	freshly	RB
cord-009417-458rrhcm	73	5	stored	store	VBN
cord-009417-458rrhcm	73	6	blood	blood	NN
cord-009417-458rrhcm	73	7	in	in	IN
cord-009417-458rrhcm	73	8	citrate	citrate	NN
cord-009417-458rrhcm	73	9	solution	solution	NN
cord-009417-458rrhcm	73	10	is	be	VBZ
cord-009417-458rrhcm	73	11	7.16	7.16	CD
cord-009417-458rrhcm	73	12	,	,	,
cord-009417-458rrhcm	73	13	which	which	WDT
cord-009417-458rrhcm	73	14	declines	decline	VBZ
cord-009417-458rrhcm	73	15	to	to	IN
cord-009417-458rrhcm	73	16	approximately	approximately	RB
cord-009417-458rrhcm	73	17	6.73	6.73	CD
cord-009417-458rrhcm	73	18	at	at	IN
cord-009417-458rrhcm	73	19	the	the	DT
cord-009417-458rrhcm	73	20	end	end	NN
cord-009417-458rrhcm	73	21	of	of	IN
cord-009417-458rrhcm	73	22	the	the	DT
cord-009417-458rrhcm	73	23	unit	unit	NN
cord-009417-458rrhcm	73	24	's	's	POS
cord-009417-458rrhcm	73	25	shelf	shelf	NN
cord-009417-458rrhcm	73	26	life	life	NN
cord-009417-458rrhcm	73	27	.	.	.
cord-009417-458rrhcm	74	1	As	as	IN
cord-009417-458rrhcm	74	2	potassium	potassium	NN
cord-009417-458rrhcm	74	3	leaks	leak	NNS
cord-009417-458rrhcm	74	4	from	from	IN
cord-009417-458rrhcm	74	5	red	red	JJ
cord-009417-458rrhcm	74	6	cells	cell	NNS
cord-009417-458rrhcm	74	7	during	during	IN
cord-009417-458rrhcm	74	8	storage	storage	NN
cord-009417-458rrhcm	74	9	,	,	,
cord-009417-458rrhcm	74	10	levels	level	NNS
cord-009417-458rrhcm	74	11	as	as	RB
cord-009417-458rrhcm	74	12	high	high	JJ
cord-009417-458rrhcm	74	13	as	as	IN
cord-009417-458rrhcm	75	1	25	25	CD
cord-009417-458rrhcm	75	2	mEq	mEq	NNS
cord-009417-458rrhcm	75	3	/	/	SYM
cord-009417-458rrhcm	75	4	L	L	NNP
cord-009417-458rrhcm	75	5	may	may	MD
cord-009417-458rrhcm	75	6	result	result	VB
cord-009417-458rrhcm	75	7	.	.	.
cord-009417-458rrhcm	76	1	However	however	RB
cord-009417-458rrhcm	76	2	,	,	,
cord-009417-458rrhcm	76	3	each	each	DT
cord-009417-458rrhcm	76	4	unit	unit	NN
cord-009417-458rrhcm	76	5	transfused	transfuse	VBD
cord-009417-458rrhcm	76	6	supplies	supply	NNS
cord-009417-458rrhcm	76	7	at	at	IN
cord-009417-458rrhcm	76	8	most	most	JJS
cord-009417-458rrhcm	76	9	7	7	CD
cord-009417-458rrhcm	76	10	mEq	mEq	NNS
cord-009417-458rrhcm	76	11	of	of	IN
cord-009417-458rrhcm	76	12	potassium	potassium	NN
cord-009417-458rrhcm	76	13	,	,	,
cord-009417-458rrhcm	76	14	which	which	WDT
cord-009417-458rrhcm	76	15	is	be	VBZ
cord-009417-458rrhcm	76	16	well	well	RB
cord-009417-458rrhcm	76	17	tolerated	tolerate	VBN
cord-009417-458rrhcm	76	18	under	under	IN
cord-009417-458rrhcm	76	19	most	most	JJS
cord-009417-458rrhcm	76	20	circumstances	circumstance	NNS
cord-009417-458rrhcm	76	21	.	.	.
cord-009417-458rrhcm	77	1	During	during	IN
cord-009417-458rrhcm	77	2	the	the	DT
cord-009417-458rrhcm	77	3	storage	storage	NN
cord-009417-458rrhcm	77	4	period	period	NN
cord-009417-458rrhcm	77	5	there	there	EX
cord-009417-458rrhcm	77	6	is	be	VBZ
cord-009417-458rrhcm	77	7	also	also	RB
cord-009417-458rrhcm	77	8	a	a	DT
cord-009417-458rrhcm	77	9	progressive	progressive	JJ
cord-009417-458rrhcm	77	10	decrease	decrease	NN
cord-009417-458rrhcm	77	11	in	in	IN
cord-009417-458rrhcm	77	12	RBC	RBC	NNP
cord-009417-458rrhcm	77	13	-	-	HYPH
cord-009417-458rrhcm	77	14	associated	associate	VBN
cord-009417-458rrhcm	77	15	2,3-diphosphoglycerate	2,3-diphosphoglycerate	CD
cord-009417-458rrhcm	77	16	(	(	-LRB-
cord-009417-458rrhcm	77	17	2,3-DPG	2,3-dpg	CD
cord-009417-458rrhcm	77	18	)	)	-RRB-
cord-009417-458rrhcm	77	19	and	and	CC
cord-009417-458rrhcm	77	20	adenosine	adenosine	NN
cord-009417-458rrhcm	77	21	triphosphate	triphosphate	NN
cord-009417-458rrhcm	77	22	(	(	-LRB-
cord-009417-458rrhcm	77	23	ATP	ATP	NNP
cord-009417-458rrhcm	77	24	)	)	-RRB-
cord-009417-458rrhcm	77	25	.	.	.
cord-009417-458rrhcm	78	1	10	10	CD
cord-009417-458rrhcm	79	1	A	a	DT
cord-009417-458rrhcm	79	2	decrease	decrease	NN
cord-009417-458rrhcm	79	3	in	in	IN
cord-009417-458rrhcm	79	4	2,3-DPG	2,3-dpg	CD
cord-009417-458rrhcm	79	5	increases	increase	NNS
cord-009417-458rrhcm	79	6	the	the	DT
cord-009417-458rrhcm	79	7	affi	affi	JJ
cord-009417-458rrhcm	79	8	nity	nity	NN
cord-009417-458rrhcm	79	9	of	of	IN
cord-009417-458rrhcm	79	10	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	79	11	for	for	IN
cord-009417-458rrhcm	79	12	oxygen	oxygen	NN
cord-009417-458rrhcm	79	13	,	,	,
cord-009417-458rrhcm	79	14	which	which	WDT
cord-009417-458rrhcm	79	15	shifts	shift	VBZ
cord-009417-458rrhcm	79	16	the	the	DT
cord-009417-458rrhcm	79	17	oxygen	oxygen	NN
cord-009417-458rrhcm	79	18	dissociation	dissociation	NN
cord-009417-458rrhcm	79	19	curve	curve	NN
cord-009417-458rrhcm	79	20	to	to	IN
cord-009417-458rrhcm	79	21	the	the	DT
cord-009417-458rrhcm	79	22	left	left	NN
cord-009417-458rrhcm	79	23	and	and	CC
cord-009417-458rrhcm	79	24	decreases	decrease	VBZ
cord-009417-458rrhcm	79	25	oxygen	oxygen	NN
cord-009417-458rrhcm	79	26	delivery	delivery	NN
cord-009417-458rrhcm	79	27	to	to	IN
cord-009417-458rrhcm	79	28	tissues	tissue	NNS
cord-009417-458rrhcm	79	29	.	.	.
cord-009417-458rrhcm	80	1	There	there	EX
cord-009417-458rrhcm	80	2	is	be	VBZ
cord-009417-458rrhcm	80	3	little	little	JJ
cord-009417-458rrhcm	80	4	evidence	evidence	NN
cord-009417-458rrhcm	80	5	,	,	,
cord-009417-458rrhcm	80	6	however	however	RB
cord-009417-458rrhcm	80	7	,	,	,
cord-009417-458rrhcm	80	8	that	that	IN
cord-009417-458rrhcm	80	9	this	this	DT
cord-009417-458rrhcm	80	10	transient	transient	JJ
cord-009417-458rrhcm	80	11	increase	increase	NN
cord-009417-458rrhcm	80	12	in	in	IN
cord-009417-458rrhcm	80	13	oxygen	oxygen	NN
cord-009417-458rrhcm	80	14	affi	affi	NNP
cord-009417-458rrhcm	80	15	nity	nity	NNP
cord-009417-458rrhcm	80	16	has	have	VBZ
cord-009417-458rrhcm	80	17	clinical	clinical	JJ
cord-009417-458rrhcm	80	18	importance	importance	NN
cord-009417-458rrhcm	80	19	.	.	.
cord-009417-458rrhcm	81	1	After	after	IN
cord-009417-458rrhcm	81	2	infusion	infusion	NN
cord-009417-458rrhcm	81	3	,	,	,
cord-009417-458rrhcm	81	4	2,3-DPG	2,3-dpg	CD
cord-009417-458rrhcm	81	5	gradually	gradually	RB
cord-009417-458rrhcm	81	6	increases	increase	VBZ
cord-009417-458rrhcm	81	7	as	as	IN
cord-009417-458rrhcm	81	8	the	the	DT
cord-009417-458rrhcm	81	9	transfused	transfuse	VBN
cord-009417-458rrhcm	81	10	red	red	JJ
cord-009417-458rrhcm	81	11	cells	cell	NNS
cord-009417-458rrhcm	81	12	circulate	circulate	VBP
cord-009417-458rrhcm	81	13	,	,	,
cord-009417-458rrhcm	81	14	with	with	IN
cord-009417-458rrhcm	81	15	25	25	CD
cord-009417-458rrhcm	81	16	%	%	NN
cord-009417-458rrhcm	81	17	recovery	recovery	NN
cord-009417-458rrhcm	81	18	in	in	IN
cord-009417-458rrhcm	81	19	8	8	CD
cord-009417-458rrhcm	81	20	hours	hour	NNS
cord-009417-458rrhcm	81	21	and	and	CC
cord-009417-458rrhcm	81	22	full	full	JJ
cord-009417-458rrhcm	81	23	replacement	replacement	NN
cord-009417-458rrhcm	81	24	by	by	IN
cord-009417-458rrhcm	81	25	24	24	CD
cord-009417-458rrhcm	81	26	hours	hour	NNS
cord-009417-458rrhcm	81	27	.	.	.
cord-009417-458rrhcm	82	1	11	11	CD
cord-009417-458rrhcm	82	2	Decreased	decrease	VBD
cord-009417-458rrhcm	82	3	ATP	ATP	NNP
cord-009417-458rrhcm	82	4	during	during	IN
cord-009417-458rrhcm	82	5	storage	storage	NN
cord-009417-458rrhcm	82	6	diminishes	diminish	VBZ
cord-009417-458rrhcm	82	7	the	the	DT
cord-009417-458rrhcm	82	8	viability	viability	NN
cord-009417-458rrhcm	82	9	of	of	IN
cord-009417-458rrhcm	82	10	red	red	JJ
cord-009417-458rrhcm	82	11	cells	cell	NNS
cord-009417-458rrhcm	82	12	after	after	IN
cord-009417-458rrhcm	82	13	transfusion	transfusion	NN
cord-009417-458rrhcm	82	14	and	and	CC
cord-009417-458rrhcm	82	15	is	be	VBZ
cord-009417-458rrhcm	82	16	one	one	CD
cord-009417-458rrhcm	82	17	of	of	IN
cord-009417-458rrhcm	82	18	the	the	DT
cord-009417-458rrhcm	82	19	chief	chief	JJ
cord-009417-458rrhcm	82	20	factors	factor	NNS
cord-009417-458rrhcm	82	21	limiting	limit	VBG
cord-009417-458rrhcm	82	22	storage	storage	NN
cord-009417-458rrhcm	82	23	time	time	NN
cord-009417-458rrhcm	82	24	.	.	.
cord-009417-458rrhcm	83	1	There	there	EX
cord-009417-458rrhcm	83	2	is	be	VBZ
cord-009417-458rrhcm	83	3	no	no	DT
cord-009417-458rrhcm	83	4	currently	currently	RB
cord-009417-458rrhcm	83	5	available	available	JJ
cord-009417-458rrhcm	83	6	storage	storage	NN
cord-009417-458rrhcm	83	7	or	or	CC
cord-009417-458rrhcm	83	8	rejuvenation	rejuvenation	NN
cord-009417-458rrhcm	83	9	solution	solution	NN
cord-009417-458rrhcm	83	10	that	that	WDT
cord-009417-458rrhcm	83	11	optimizes	optimize	VBZ
cord-009417-458rrhcm	83	12	these	these	DT
cord-009417-458rrhcm	83	13	cellular	cellular	JJ
cord-009417-458rrhcm	83	14	constituents	constituent	NNS
cord-009417-458rrhcm	83	15	.	.	.
cord-009417-458rrhcm	84	1	The	the	DT
cord-009417-458rrhcm	84	2	majority	majority	NN
cord-009417-458rrhcm	84	3	of	of	IN
cord-009417-458rrhcm	84	4	blood	blood	NN
cord-009417-458rrhcm	84	5	transfusions	transfusion	NNS
cord-009417-458rrhcm	84	6	are	be	VBP
cord-009417-458rrhcm	84	7	in	in	IN
cord-009417-458rrhcm	84	8	the	the	DT
cord-009417-458rrhcm	84	9	form	form	NN
cord-009417-458rrhcm	84	10	of	of	IN
cord-009417-458rrhcm	84	11	PRBCs	prbc	NNS
cord-009417-458rrhcm	84	12	,	,	,
cord-009417-458rrhcm	84	13	the	the	DT
cord-009417-458rrhcm	84	14	component	component	NN
cord-009417-458rrhcm	84	15	indicated	indicate	VBD
cord-009417-458rrhcm	84	16	for	for	IN
cord-009417-458rrhcm	84	17	normovolemic	normovolemic	JJ
cord-009417-458rrhcm	84	18	patients	patient	NNS
cord-009417-458rrhcm	84	19	or	or	CC
cord-009417-458rrhcm	84	20	those	those	DT
cord-009417-458rrhcm	84	21	for	for	IN
cord-009417-458rrhcm	84	22	whom	whom	WP
cord-009417-458rrhcm	84	23	intravascular	intravascular	JJ
cord-009417-458rrhcm	84	24	volume	volume	NN
cord-009417-458rrhcm	84	25	constraints	constraint	NNS
cord-009417-458rrhcm	84	26	are	be	VBP
cord-009417-458rrhcm	84	27	necessary	necessary	JJ
cord-009417-458rrhcm	84	28	.	.	.
cord-009417-458rrhcm	85	1	The	the	DT
cord-009417-458rrhcm	85	2	use	use	NN
cord-009417-458rrhcm	85	3	of	of	IN
cord-009417-458rrhcm	85	4	WB	WB	NNP
cord-009417-458rrhcm	85	5	may	may	MD
cord-009417-458rrhcm	85	6	be	be	VB
cord-009417-458rrhcm	85	7	desirable	desirable	JJ
cord-009417-458rrhcm	85	8	for	for	IN
cord-009417-458rrhcm	85	9	patients	patient	NNS
cord-009417-458rrhcm	85	10	who	who	WP
cord-009417-458rrhcm	85	11	require	require	VBP
cord-009417-458rrhcm	85	12	both	both	DT
cord-009417-458rrhcm	85	13	increased	increase	VBN
cord-009417-458rrhcm	85	14	oxygen	oxygen	NN
cord-009417-458rrhcm	85	15	-	-	HYPH
cord-009417-458rrhcm	85	16	carrying	carry	VBG
cord-009417-458rrhcm	85	17	capacity	capacity	NN
cord-009417-458rrhcm	85	18	and	and	CC
cord-009417-458rrhcm	85	19	volume	volume	NN
cord-009417-458rrhcm	85	20	resuscitation	resuscitation	NN
cord-009417-458rrhcm	85	21	because	because	IN
cord-009417-458rrhcm	85	22	of	of	IN
cord-009417-458rrhcm	85	23	a	a	DT
cord-009417-458rrhcm	85	24	large	large	JJ
cord-009417-458rrhcm	85	25	and	and	CC
cord-009417-458rrhcm	85	26	ongoing	ongoing	JJ
cord-009417-458rrhcm	85	27	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	85	28	;	;	:
cord-009417-458rrhcm	85	29	however	however	RB
cord-009417-458rrhcm	85	30	,	,	,
cord-009417-458rrhcm	85	31	the	the	DT
cord-009417-458rrhcm	85	32	availability	availability	NN
cord-009417-458rrhcm	85	33	of	of	IN
cord-009417-458rrhcm	85	34	WB	WB	NNP
cord-009417-458rrhcm	85	35	is	be	VBZ
cord-009417-458rrhcm	85	36	generally	generally	RB
cord-009417-458rrhcm	85	37	limited	limited	JJ
cord-009417-458rrhcm	85	38	.	.	.
cord-009417-458rrhcm	86	1	Resuscitation	resuscitation	NN
cord-009417-458rrhcm	86	2	is	be	VBZ
cord-009417-458rrhcm	86	3	effectively	effectively	RB
cord-009417-458rrhcm	86	4	achieved	achieve	VBN
cord-009417-458rrhcm	86	5	with	with	IN
cord-009417-458rrhcm	86	6	the	the	DT
cord-009417-458rrhcm	86	7	use	use	NN
cord-009417-458rrhcm	86	8	of	of	IN
cord-009417-458rrhcm	86	9	PRBCs	prbc	NNS
cord-009417-458rrhcm	86	10	and	and	CC
cord-009417-458rrhcm	86	11	crystalloid	crystalloid	NN
cord-009417-458rrhcm	86	12	solutions	solution	NNS
cord-009417-458rrhcm	86	13	.	.	.
cord-009417-458rrhcm	87	1	Each	each	DT
cord-009417-458rrhcm	87	2	unit	unit	NN
cord-009417-458rrhcm	87	3	of	of	IN
cord-009417-458rrhcm	87	4	PRBCs	PRBCs	NNPS
cord-009417-458rrhcm	87	5	or	or	CC
cord-009417-458rrhcm	87	6	WB	WB	NNP
cord-009417-458rrhcm	87	7	is	be	VBZ
cord-009417-458rrhcm	87	8	expected	expect	VBN
cord-009417-458rrhcm	87	9	to	to	TO
cord-009417-458rrhcm	87	10	raise	raise	VB
cord-009417-458rrhcm	87	11	the	the	DT
cord-009417-458rrhcm	87	12	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	87	13	level	level	NN
cord-009417-458rrhcm	87	14	by	by	IN
cord-009417-458rrhcm	87	15	1	1	CD
cord-009417-458rrhcm	87	16	g	g	NN
cord-009417-458rrhcm	87	17	/	/	SYM
cord-009417-458rrhcm	87	18	dL	dl	NN
cord-009417-458rrhcm	87	19	and	and	CC
cord-009417-458rrhcm	87	20	the	the	DT
cord-009417-458rrhcm	87	21	Hct	Hct	NNP
cord-009417-458rrhcm	87	22	by	by	IN
cord-009417-458rrhcm	87	23	3	3	CD
cord-009417-458rrhcm	87	24	%	%	NN
cord-009417-458rrhcm	87	25	in	in	IN
cord-009417-458rrhcm	87	26	stable	stable	JJ
cord-009417-458rrhcm	87	27	,	,	,
cord-009417-458rrhcm	87	28	nonbleeding	nonbleeding	NN
cord-009417-458rrhcm	87	29	,	,	,
cord-009417-458rrhcm	87	30	average	average	JJ
cord-009417-458rrhcm	87	31	-	-	HYPH
cord-009417-458rrhcm	87	32	sized	sized	JJ
cord-009417-458rrhcm	87	33	adults	adult	NNS
cord-009417-458rrhcm	87	34	.	.	.
cord-009417-458rrhcm	88	1	Although	although	IN
cord-009417-458rrhcm	88	2	some	some	DT
cord-009417-458rrhcm	88	3	studies	study	NNS
cord-009417-458rrhcm	88	4	have	have	VBP
cord-009417-458rrhcm	88	5	demonstrated	demonstrate	VBN
cord-009417-458rrhcm	88	6	a	a	DT
cord-009417-458rrhcm	88	7	slight	slight	JJ
cord-009417-458rrhcm	88	8	superiority	superiority	NN
cord-009417-458rrhcm	88	9	of	of	IN
cord-009417-458rrhcm	88	10	fresh	fresh	JJ
cord-009417-458rrhcm	88	11	WB	WB	NNP
cord-009417-458rrhcm	88	12	over	over	IN
cord-009417-458rrhcm	88	13	components	component	NNS
cord-009417-458rrhcm	88	14	when	when	WRB
cord-009417-458rrhcm	88	15	used	use	VBN
cord-009417-458rrhcm	88	16	during	during	IN
cord-009417-458rrhcm	88	17	cardiac	cardiac	JJ
cord-009417-458rrhcm	88	18	surgery	surgery	NN
cord-009417-458rrhcm	88	19	in	in	IN
cord-009417-458rrhcm	88	20	selected	select	VBN
cord-009417-458rrhcm	88	21	patients	patient	NNS
cord-009417-458rrhcm	88	22	,	,	,
cord-009417-458rrhcm	88	23	12	12	CD
cord-009417-458rrhcm	88	24	the	the	DT
cord-009417-458rrhcm	88	25	benefi	benefi	JJ
cord-009417-458rrhcm	88	26	ts	ts	NN
cord-009417-458rrhcm	88	27	of	of	IN
cord-009417-458rrhcm	88	28	fresh	fresh	JJ
cord-009417-458rrhcm	88	29	blood	blood	NN
cord-009417-458rrhcm	88	30	remain	remain	VBP
cord-009417-458rrhcm	88	31	controversial	controversial	JJ
cord-009417-458rrhcm	88	32	,	,	,
cord-009417-458rrhcm	88	33	and	and	CC
cord-009417-458rrhcm	88	34	current	current	JJ
cord-009417-458rrhcm	88	35	testing	testing	NN
cord-009417-458rrhcm	88	36	and	and	CC
cord-009417-458rrhcm	88	37	processing	processing	NN
cord-009417-458rrhcm	88	38	requirements	requirement	NNS
cord-009417-458rrhcm	88	39	limit	limit	VBP
cord-009417-458rrhcm	88	40	general	general	JJ
cord-009417-458rrhcm	88	41	availability	availability	NN
cord-009417-458rrhcm	88	42	.	.	.
cord-009417-458rrhcm	89	1	Despite	despite	IN
cord-009417-458rrhcm	89	2	a	a	DT
cord-009417-458rrhcm	89	3	long	long	JJ
cord-009417-458rrhcm	89	4	tradition	tradition	NN
cord-009417-458rrhcm	89	5	of	of	IN
cord-009417-458rrhcm	89	6	transfusion	transfusion	NN
cord-009417-458rrhcm	89	7	of	of	IN
cord-009417-458rrhcm	89	8	RBCs	rbc	NNS
cord-009417-458rrhcm	89	9	in	in	IN
cord-009417-458rrhcm	89	10	critically	critically	RB
cord-009417-458rrhcm	89	11	ill	ill	JJ
cord-009417-458rrhcm	89	12	patients	patient	NNS
cord-009417-458rrhcm	89	13	,	,	,
cord-009417-458rrhcm	89	14	the	the	DT
cord-009417-458rrhcm	89	15	precise	precise	JJ
cord-009417-458rrhcm	89	16	indications	indication	NNS
cord-009417-458rrhcm	89	17	for	for	IN
cord-009417-458rrhcm	89	18	transfusion	transfusion	NN
cord-009417-458rrhcm	89	19	remain	remain	VBP
cord-009417-458rrhcm	89	20	a	a	DT
cord-009417-458rrhcm	89	21	source	source	NN
cord-009417-458rrhcm	89	22	of	of	IN
cord-009417-458rrhcm	89	23	controversy	controversy	NN
cord-009417-458rrhcm	89	24	,	,	,
cord-009417-458rrhcm	89	25	and	and	CC
cord-009417-458rrhcm	89	26	specifi	specifi	NNP
cord-009417-458rrhcm	89	27	c	c	NNP
cord-009417-458rrhcm	89	28	transfusion	transfusion	NN
cord-009417-458rrhcm	89	29	practices	practice	NNS
cord-009417-458rrhcm	89	30	may	may	MD
cord-009417-458rrhcm	89	31	vary	vary	VB
cord-009417-458rrhcm	89	32	widely	widely	RB
cord-009417-458rrhcm	89	33	among	among	IN
cord-009417-458rrhcm	89	34	clinicians	clinician	NNS
cord-009417-458rrhcm	89	35	.	.	.
cord-009417-458rrhcm	90	1	Before	before	IN
cord-009417-458rrhcm	90	2	the	the	DT
cord-009417-458rrhcm	90	3	major	major	JJ
cord-009417-458rrhcm	90	4	randomized	randomized	JJ
cord-009417-458rrhcm	90	5	studies	study	NNS
cord-009417-458rrhcm	90	6	of	of	IN
cord-009417-458rrhcm	90	7	RBC	RBC	NNP
cord-009417-458rrhcm	90	8	transfusion	transfusion	NN
cord-009417-458rrhcm	90	9	policies	policy	NNS
cord-009417-458rrhcm	90	10	,	,	,
cord-009417-458rrhcm	90	11	a	a	DT
cord-009417-458rrhcm	90	12	survey	survey	NN
cord-009417-458rrhcm	90	13	of	of	IN
cord-009417-458rrhcm	90	14	transfusion	transfusion	NN
cord-009417-458rrhcm	90	15	practice	practice	NN
cord-009417-458rrhcm	90	16	showed	show	VBD
cord-009417-458rrhcm	90	17	that	that	IN
cord-009417-458rrhcm	90	18	about	about	IN
cord-009417-458rrhcm	90	19	half	half	NN
cord-009417-458rrhcm	90	20	of	of	IN
cord-009417-458rrhcm	90	21	ICU	ICU	NNP
cord-009417-458rrhcm	90	22	patients	patient	NNS
cord-009417-458rrhcm	90	23	were	be	VBD
cord-009417-458rrhcm	90	24	receiving	receive	VBG
cord-009417-458rrhcm	90	25	red	red	JJ
cord-009417-458rrhcm	90	26	cell	cell	NN
cord-009417-458rrhcm	90	27	transfusions	transfusion	NNS
cord-009417-458rrhcm	90	28	,	,	,
cord-009417-458rrhcm	90	29	13	13	CD
cord-009417-458rrhcm	90	30	and	and	CC
cord-009417-458rrhcm	90	31	another	another	DT
cord-009417-458rrhcm	90	32	showed	show	VBD
cord-009417-458rrhcm	90	33	that	that	IN
cord-009417-458rrhcm	90	34	if	if	IN
cord-009417-458rrhcm	90	35	the	the	DT
cord-009417-458rrhcm	90	36	ICU	ICU	NNP
cord-009417-458rrhcm	90	37	stay	stay	NN
cord-009417-458rrhcm	90	38	was	be	VBD
cord-009417-458rrhcm	90	39	longer	long	JJR
cord-009417-458rrhcm	90	40	than	than	IN
cord-009417-458rrhcm	90	41	a	a	DT
cord-009417-458rrhcm	90	42	week	week	NN
cord-009417-458rrhcm	90	43	,	,	,
cord-009417-458rrhcm	90	44	the	the	DT
cord-009417-458rrhcm	90	45	rate	rate	NN
cord-009417-458rrhcm	90	46	of	of	IN
cord-009417-458rrhcm	90	47	transfusion	transfusion	NN
cord-009417-458rrhcm	90	48	was	be	VBD
cord-009417-458rrhcm	90	49	85	85	CD
cord-009417-458rrhcm	90	50	%	%	NN
cord-009417-458rrhcm	90	51	.	.	.
cord-009417-458rrhcm	91	1	14	14	CD
cord-009417-458rrhcm	92	1	The	the	DT
cord-009417-458rrhcm	92	2	total	total	JJ
cord-009417-458rrhcm	92	3	number	number	NN
cord-009417-458rrhcm	92	4	of	of	IN
cord-009417-458rrhcm	92	5	transfusions	transfusion	NNS
cord-009417-458rrhcm	92	6	was	be	VBD
cord-009417-458rrhcm	92	7	high	high	JJ
cord-009417-458rrhcm	92	8	,	,	,
cord-009417-458rrhcm	92	9	and	and	CC
cord-009417-458rrhcm	92	10	ICU	ICU	NNP
cord-009417-458rrhcm	92	11	practice	practice	NN
cord-009417-458rrhcm	92	12	was	be	VBD
cord-009417-458rrhcm	92	13	characterized	characterize	VBN
cord-009417-458rrhcm	92	14	by	by	IN
cord-009417-458rrhcm	92	15	high	high	JJ
cord-009417-458rrhcm	92	16	rates	rate	NNS
cord-009417-458rrhcm	92	17	of	of	IN
cord-009417-458rrhcm	92	18	transfusion	transfusion	NN
cord-009417-458rrhcm	92	19	.	.	.
cord-009417-458rrhcm	93	1	15	15	CD
cord-009417-458rrhcm	94	1	The	the	DT
cord-009417-458rrhcm	94	2	reasons	reason	NNS
cord-009417-458rrhcm	94	3	for	for	IN
cord-009417-458rrhcm	94	4	the	the	DT
cord-009417-458rrhcm	94	5	controversies	controversy	NNS
cord-009417-458rrhcm	94	6	are	be	VBP
cord-009417-458rrhcm	94	7	clear	clear	JJ
cord-009417-458rrhcm	94	8	:	:	:
cord-009417-458rrhcm	94	9	RBCs	rbc	NNS
cord-009417-458rrhcm	94	10	should	should	MD
cord-009417-458rrhcm	94	11	be	be	VB
cord-009417-458rrhcm	94	12	transfused	transfuse	VBN
cord-009417-458rrhcm	94	13	only	only	RB
cord-009417-458rrhcm	94	14	to	to	TO
cord-009417-458rrhcm	94	15	enhance	enhance	VB
cord-009417-458rrhcm	94	16	tissue	tissue	NN
cord-009417-458rrhcm	94	17	oxygen	oxygen	NN
cord-009417-458rrhcm	94	18	delivery	delivery	NN
cord-009417-458rrhcm	94	19	,	,	,
cord-009417-458rrhcm	94	20	but	but	CC
cord-009417-458rrhcm	94	21	the	the	DT
cord-009417-458rrhcm	94	22	underlying	underlying	JJ
cord-009417-458rrhcm	94	23	physiology	physiology	NN
cord-009417-458rrhcm	94	24	of	of	IN
cord-009417-458rrhcm	94	25	anemia	anemia	NN
cord-009417-458rrhcm	94	26	,	,	,
cord-009417-458rrhcm	94	27	the	the	DT
cord-009417-458rrhcm	94	28	complex	complex	JJ
cord-009417-458rrhcm	94	29	adaptations	adaptation	NNS
cord-009417-458rrhcm	94	30	to	to	IN
cord-009417-458rrhcm	94	31	anemia	anemia	NN
cord-009417-458rrhcm	94	32	,	,	,
cord-009417-458rrhcm	94	33	and	and	CC
cord-009417-458rrhcm	94	34	the	the	DT
cord-009417-458rrhcm	94	35	potential	potential	JJ
cord-009417-458rrhcm	94	36	advantages	advantage	NNS
cord-009417-458rrhcm	94	37	and	and	CC
cord-009417-458rrhcm	94	38	disadvantages	disadvantage	NNS
cord-009417-458rrhcm	94	39	to	to	IN
cord-009417-458rrhcm	94	40	particular	particular	JJ
cord-009417-458rrhcm	94	41	groups	group	NNS
cord-009417-458rrhcm	94	42	of	of	IN
cord-009417-458rrhcm	94	43	patients	patient	NNS
cord-009417-458rrhcm	94	44	are	be	VBP
cord-009417-458rrhcm	94	45	not	not	RB
cord-009417-458rrhcm	94	46	as	as	RB
cord-009417-458rrhcm	94	47	well	well	RB
cord-009417-458rrhcm	94	48	understood	understand	VBN
cord-009417-458rrhcm	94	49	.	.	.
cord-009417-458rrhcm	95	1	Compensatory	compensatory	JJ
cord-009417-458rrhcm	95	2	mechanisms	mechanism	NNS
cord-009417-458rrhcm	95	3	for	for	IN
cord-009417-458rrhcm	95	4	acute	acute	JJ
cord-009417-458rrhcm	95	5	and	and	CC
cord-009417-458rrhcm	95	6	chronic	chronic	JJ
cord-009417-458rrhcm	95	7	anemia	anemia	NN
cord-009417-458rrhcm	95	8	are	be	VBP
cord-009417-458rrhcm	95	9	diverse	diverse	JJ
cord-009417-458rrhcm	95	10	and	and	CC
cord-009417-458rrhcm	95	11	complex	complex	JJ
cord-009417-458rrhcm	95	12	.	.	.
cord-009417-458rrhcm	96	1	16	16	CD
cord-009417-458rrhcm	96	2	,	,	,
cord-009417-458rrhcm	96	3	17	17	CD
cord-009417-458rrhcm	97	1	All	all	DT
cord-009417-458rrhcm	97	2	work	work	NN
cord-009417-458rrhcm	97	3	in	in	IN
cord-009417-458rrhcm	97	4	concert	concert	NN
cord-009417-458rrhcm	97	5	to	to	TO
cord-009417-458rrhcm	97	6	maintain	maintain	VB
cord-009417-458rrhcm	97	7	oxygenation	oxygenation	NN
cord-009417-458rrhcm	97	8	within	within	IN
cord-009417-458rrhcm	97	9	the	the	DT
cord-009417-458rrhcm	97	10	microcirculation	microcirculation	NN
cord-009417-458rrhcm	97	11	.	.	.
cord-009417-458rrhcm	98	1	Cardiovascular	cardiovascular	JJ
cord-009417-458rrhcm	98	2	adjustments	adjustment	NNS
cord-009417-458rrhcm	98	3	leading	lead	VBG
cord-009417-458rrhcm	98	4	to	to	IN
cord-009417-458rrhcm	98	5	increased	increase	VBN
cord-009417-458rrhcm	98	6	cardiac	cardiac	JJ
cord-009417-458rrhcm	98	7	output	output	NN
cord-009417-458rrhcm	98	8	include	include	VBP
cord-009417-458rrhcm	98	9	decreased	decrease	VBN
cord-009417-458rrhcm	98	10	afterload	afterload	NN
cord-009417-458rrhcm	98	11	and	and	CC
cord-009417-458rrhcm	98	12	increased	increase	VBN
cord-009417-458rrhcm	98	13	preload	preload	NN
cord-009417-458rrhcm	98	14	resulting	result	VBG
cord-009417-458rrhcm	98	15	from	from	IN
cord-009417-458rrhcm	98	16	changes	change	NNS
cord-009417-458rrhcm	98	17	in	in	IN
cord-009417-458rrhcm	98	18	vascular	vascular	JJ
cord-009417-458rrhcm	98	19	tone	tone	NN
cord-009417-458rrhcm	98	20	,	,	,
cord-009417-458rrhcm	98	21	increased	increase	VBN
cord-009417-458rrhcm	98	22	myocardial	myocardial	JJ
cord-009417-458rrhcm	98	23	contractility	contractility	NN
cord-009417-458rrhcm	98	24	,	,	,
cord-009417-458rrhcm	98	25	and	and	CC
cord-009417-458rrhcm	98	26	elevated	elevated	JJ
cord-009417-458rrhcm	98	27	heart	heart	NN
cord-009417-458rrhcm	98	28	rate	rate	NN
cord-009417-458rrhcm	98	29	.	.	.
cord-009417-458rrhcm	99	1	Lowered	lower	VBN
cord-009417-458rrhcm	99	2	blood	blood	NN
cord-009417-458rrhcm	99	3	viscosity	viscosity	NN
cord-009417-458rrhcm	99	4	permits	permit	NNS
cord-009417-458rrhcm	99	5	improved	improve	VBN
cord-009417-458rrhcm	99	6	fl	fl	NNP
cord-009417-458rrhcm	99	7	ow	ow	NN
cord-009417-458rrhcm	99	8	of	of	IN
cord-009417-458rrhcm	99	9	erythrocytes	erythrocyte	NNS
cord-009417-458rrhcm	99	10	within	within	IN
cord-009417-458rrhcm	99	11	capillaries	capillary	NNS
cord-009417-458rrhcm	99	12	.	.	.
cord-009417-458rrhcm	100	1	Blood	blood	NN
cord-009417-458rrhcm	100	2	fl	fl	NNP
cord-009417-458rrhcm	100	3	ow	ow	NN
cord-009417-458rrhcm	100	4	is	be	VBZ
cord-009417-458rrhcm	100	5	redistributed	redistribute	VBN
cord-009417-458rrhcm	100	6	to	to	TO
cord-009417-458rrhcm	100	7	favor	favor	VB
cord-009417-458rrhcm	100	8	critical	critical	JJ
cord-009417-458rrhcm	100	9	organs	organ	NNS
cord-009417-458rrhcm	100	10	with	with	IN
cord-009417-458rrhcm	100	11	higher	high	JJR
cord-009417-458rrhcm	100	12	oxygen	oxygen	NN
cord-009417-458rrhcm	100	13	extraction	extraction	NN
cord-009417-458rrhcm	100	14	.	.	.
cord-009417-458rrhcm	101	1	Pulmonary	pulmonary	JJ
cord-009417-458rrhcm	101	2	mechanisms	mechanism	NNS
cord-009417-458rrhcm	101	3	,	,	,
cord-009417-458rrhcm	101	4	though	though	IN
cord-009417-458rrhcm	101	5	contributing	contribute	VBG
cord-009417-458rrhcm	101	6	relatively	relatively	RB
cord-009417-458rrhcm	101	7	little	little	JJ
cord-009417-458rrhcm	101	8	to	to	IN
cord-009417-458rrhcm	101	9	shortterm	shortterm	JJ
cord-009417-458rrhcm	101	10	oxygenation	oxygenation	NN
cord-009417-458rrhcm	101	11	demands	demand	NNS
cord-009417-458rrhcm	101	12	,	,	,
cord-009417-458rrhcm	101	13	exert	exert	VB
cord-009417-458rrhcm	101	14	potent	potent	JJ
cord-009417-458rrhcm	101	15	effects	effect	NNS
cord-009417-458rrhcm	101	16	on	on	IN
cord-009417-458rrhcm	101	17	related	relate	VBN
cord-009417-458rrhcm	101	18	metabolic	metabolic	JJ
cord-009417-458rrhcm	101	19	variables	variable	NNS
cord-009417-458rrhcm	101	20	.	.	.
cord-009417-458rrhcm	102	1	Finally	finally	RB
cord-009417-458rrhcm	102	2	,	,	,
cord-009417-458rrhcm	102	3	the	the	DT
cord-009417-458rrhcm	102	4	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	102	5	molecule	molecule	NN
cord-009417-458rrhcm	102	6	can	can	MD
cord-009417-458rrhcm	102	7	undergo	undergo	VB
cord-009417-458rrhcm	102	8	biochemical	biochemical	JJ
cord-009417-458rrhcm	102	9	and	and	CC
cord-009417-458rrhcm	102	10	conformational	conformational	JJ
cord-009417-458rrhcm	102	11	changes	change	NNS
cord-009417-458rrhcm	102	12	to	to	TO
cord-009417-458rrhcm	102	13	enhance	enhance	VB
cord-009417-458rrhcm	102	14	unloading	unloading	NN
cord-009417-458rrhcm	102	15	of	of	IN
cord-009417-458rrhcm	102	16	oxygen	oxygen	NN
cord-009417-458rrhcm	102	17	at	at	IN
cord-009417-458rrhcm	102	18	the	the	DT
cord-009417-458rrhcm	102	19	capillary	capillary	JJ
cord-009417-458rrhcm	102	20	level	level	NN
cord-009417-458rrhcm	102	21	.	.	.
cord-009417-458rrhcm	103	1	All	all	PDT
cord-009417-458rrhcm	103	2	these	these	DT
cord-009417-458rrhcm	103	3	mechanisms	mechanism	NNS
cord-009417-458rrhcm	103	4	contribute	contribute	VBP
cord-009417-458rrhcm	103	5	to	to	IN
cord-009417-458rrhcm	103	6	an	an	DT
cord-009417-458rrhcm	103	7	"	"	``
cord-009417-458rrhcm	103	8	oxygen	oxygen	NN
cord-009417-458rrhcm	103	9	reserve	reserve	NN
cord-009417-458rrhcm	103	10	"	"	''
cord-009417-458rrhcm	103	11	capacity	capacity	NN
cord-009417-458rrhcm	103	12	that	that	WDT
cord-009417-458rrhcm	103	13	exceeds	exceed	VBZ
cord-009417-458rrhcm	103	14	baseline	baseline	JJ
cord-009417-458rrhcm	103	15	requirements	requirement	NNS
cord-009417-458rrhcm	103	16	by	by	IN
cord-009417-458rrhcm	103	17	approximately	approximately	RB
cord-009417-458rrhcm	103	18	fourfold	fourfold	JJ
cord-009417-458rrhcm	103	19	.	.	.
cord-009417-458rrhcm	104	1	16	16	CD
cord-009417-458rrhcm	105	1	No	no	DT
cord-009417-458rrhcm	105	2	experimental	experimental	JJ
cord-009417-458rrhcm	105	3	model	model	NN
cord-009417-458rrhcm	105	4	exists	exist	VBZ
cord-009417-458rrhcm	105	5	that	that	WDT
cord-009417-458rrhcm	105	6	encompasses	encompass	VBZ
cord-009417-458rrhcm	105	7	the	the	DT
cord-009417-458rrhcm	105	8	diversity	diversity	NN
cord-009417-458rrhcm	105	9	of	of	IN
cord-009417-458rrhcm	105	10	physiologic	physiologic	JJ
cord-009417-458rrhcm	105	11	compensations	compensation	NNS
cord-009417-458rrhcm	105	12	for	for	IN
cord-009417-458rrhcm	105	13	hypoxia	hypoxia	NN
cord-009417-458rrhcm	105	14	.	.	.
cord-009417-458rrhcm	106	1	Experiments	experiment	NNS
cord-009417-458rrhcm	106	2	carried	carry	VBD
cord-009417-458rrhcm	106	3	out	out	RP
cord-009417-458rrhcm	106	4	in	in	IN
cord-009417-458rrhcm	106	5	animals	animal	NNS
cord-009417-458rrhcm	106	6	and	and	CC
cord-009417-458rrhcm	106	7	case	case	NN
cord-009417-458rrhcm	106	8	reports	report	NNS
cord-009417-458rrhcm	106	9	in	in	IN
cord-009417-458rrhcm	106	10	patients	patient	NNS
cord-009417-458rrhcm	106	11	refusing	refuse	VBG
cord-009417-458rrhcm	106	12	transfusion	transfusion	NN
cord-009417-458rrhcm	106	13	indicate	indicate	VBP
cord-009417-458rrhcm	106	14	that	that	IN
cord-009417-458rrhcm	106	15	an	an	DT
cord-009417-458rrhcm	106	16	extremely	extremely	RB
cord-009417-458rrhcm	106	17	low	low	JJ
cord-009417-458rrhcm	106	18	Hct	Hct	NNP
cord-009417-458rrhcm	106	19	is	be	VBZ
cord-009417-458rrhcm	106	20	tolerated	tolerate	VBN
cord-009417-458rrhcm	106	21	if	if	IN
cord-009417-458rrhcm	106	22	tissue	tissue	NN
cord-009417-458rrhcm	106	23	perfusion	perfusion	NN
cord-009417-458rrhcm	106	24	is	be	VBZ
cord-009417-458rrhcm	106	25	adequate	adequate	JJ
cord-009417-458rrhcm	106	26	.	.	.
cord-009417-458rrhcm	107	1	[	[	-LRB-
cord-009417-458rrhcm	107	2	18	18	CD
cord-009417-458rrhcm	107	3	]	]	-RRB-
cord-009417-458rrhcm	107	4	[	[	-LRB-
cord-009417-458rrhcm	107	5	19	19	CD
cord-009417-458rrhcm	107	6	]	]	-RRB-
cord-009417-458rrhcm	107	7	[	[	-LRB-
cord-009417-458rrhcm	107	8	20	20	CD
cord-009417-458rrhcm	107	9	]	]	-RRB-
cord-009417-458rrhcm	108	1	Certain	certain	JJ
cord-009417-458rrhcm	108	2	objective	objective	NN
cord-009417-458rrhcm	108	3	,	,	,
cord-009417-458rrhcm	108	4	though	though	IN
cord-009417-458rrhcm	108	5	indirect	indirect	JJ
cord-009417-458rrhcm	108	6	,	,	,
cord-009417-458rrhcm	108	7	measurements	measurement	NNS
cord-009417-458rrhcm	108	8	of	of	IN
cord-009417-458rrhcm	108	9	tissue	tissue	NN
cord-009417-458rrhcm	108	10	oxygenation	oxygenation	NN
cord-009417-458rrhcm	108	11	exist	exist	VBP
cord-009417-458rrhcm	108	12	and	and	CC
cord-009417-458rrhcm	108	13	are	be	VBP
cord-009417-458rrhcm	108	14	available	available	JJ
cord-009417-458rrhcm	108	15	to	to	IN
cord-009417-458rrhcm	108	16	clinicians	clinician	NNS
cord-009417-458rrhcm	108	17	caring	care	VBG
cord-009417-458rrhcm	108	18	for	for	IN
cord-009417-458rrhcm	108	19	patients	patient	NNS
cord-009417-458rrhcm	108	20	monitored	monitor	VBN
cord-009417-458rrhcm	108	21	invasively	invasively	RB
cord-009417-458rrhcm	108	22	in	in	IN
cord-009417-458rrhcm	108	23	the	the	DT
cord-009417-458rrhcm	108	24	ICU	ICU	NNP
cord-009417-458rrhcm	108	25	.	.	.
cord-009417-458rrhcm	109	1	Mixed	mixed	JJ
cord-009417-458rrhcm	109	2	venous	venous	JJ
cord-009417-458rrhcm	109	3	oxygen	oxygen	NN
cord-009417-458rrhcm	109	4	content	content	NN
cord-009417-458rrhcm	109	5	(	(	-LRB-
cord-009417-458rrhcm	109	6	Pv	Pv	NNP
cord-009417-458rrhcm	109	7	O	O	NNP
cord-009417-458rrhcm	109	8	2	2	CD
cord-009417-458rrhcm	109	9	)	)	-RRB-
cord-009417-458rrhcm	109	10	and	and	CC
cord-009417-458rrhcm	110	1	cardiac	cardiac	JJ
cord-009417-458rrhcm	110	2	output	output	NN
cord-009417-458rrhcm	110	3	can	can	MD
cord-009417-458rrhcm	110	4	be	be	VB
cord-009417-458rrhcm	110	5	measured	measure	VBN
cord-009417-458rrhcm	110	6	in	in	IN
cord-009417-458rrhcm	110	7	patients	patient	NNS
cord-009417-458rrhcm	110	8	undergoing	undergo	VBG
cord-009417-458rrhcm	110	9	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	110	10	artery	artery	NN
cord-009417-458rrhcm	110	11	catheterization	catheterization	NN
cord-009417-458rrhcm	110	12	;	;	:
cord-009417-458rrhcm	110	13	arterial	arterial	JJ
cord-009417-458rrhcm	110	14	oxygen	oxygen	NN
cord-009417-458rrhcm	110	15	content	content	NN
cord-009417-458rrhcm	110	16	can	can	MD
cord-009417-458rrhcm	110	17	also	also	RB
cord-009417-458rrhcm	110	18	be	be	VB
cord-009417-458rrhcm	110	19	measured	measure	VBN
cord-009417-458rrhcm	110	20	directly	directly	RB
cord-009417-458rrhcm	110	21	.	.	.
cord-009417-458rrhcm	111	1	The	the	DT
cord-009417-458rrhcm	111	2	oxygen	oxygen	NN
cord-009417-458rrhcm	111	3	extraction	extraction	NN
cord-009417-458rrhcm	111	4	ratio	ratio	NN
cord-009417-458rrhcm	111	5	(	(	-LRB-
cord-009417-458rrhcm	111	6	ER	ER	NNP
cord-009417-458rrhcm	111	7	)	)	-RRB-
cord-009417-458rrhcm	111	8	can	can	MD
cord-009417-458rrhcm	111	9	be	be	VB
cord-009417-458rrhcm	111	10	calculated	calculate	VBN
cord-009417-458rrhcm	111	11	directly	directly	RB
cord-009417-458rrhcm	111	12	,	,	,
cord-009417-458rrhcm	111	13	and	and	CC
cord-009417-458rrhcm	111	14	in	in	IN
cord-009417-458rrhcm	111	15	the	the	DT
cord-009417-458rrhcm	111	16	presence	presence	NN
cord-009417-458rrhcm	111	17	of	of	IN
cord-009417-458rrhcm	111	18	normal	normal	JJ
cord-009417-458rrhcm	111	19	or	or	CC
cord-009417-458rrhcm	111	20	high	high	JJ
cord-009417-458rrhcm	111	21	cardiac	cardiac	JJ
cord-009417-458rrhcm	111	22	output	output	NN
cord-009417-458rrhcm	111	23	it	-PRON-	PRP
cord-009417-458rrhcm	111	24	is	be	VBZ
cord-009417-458rrhcm	111	25	a	a	DT
cord-009417-458rrhcm	111	26	measure	measure	NN
cord-009417-458rrhcm	111	27	of	of	IN
cord-009417-458rrhcm	111	28	tissue	tissue	NN
cord-009417-458rrhcm	111	29	oxygen	oxygen	NN
cord-009417-458rrhcm	111	30	extraction	extraction	NN
cord-009417-458rrhcm	111	31	and	and	CC
cord-009417-458rrhcm	111	32	,	,	,
cord-009417-458rrhcm	111	33	indirectly	indirectly	RB
cord-009417-458rrhcm	111	34	,	,	,
cord-009417-458rrhcm	111	35	the	the	DT
cord-009417-458rrhcm	111	36	adequacy	adequacy	NN
cord-009417-458rrhcm	111	37	of	of	IN
cord-009417-458rrhcm	111	38	tissue	tissue	NN
cord-009417-458rrhcm	111	39	oxygen	oxygen	NN
cord-009417-458rrhcm	111	40	delivery	delivery	NN
cord-009417-458rrhcm	111	41	.	.	.
cord-009417-458rrhcm	112	1	The	the	DT
cord-009417-458rrhcm	112	2	total	total	JJ
cord-009417-458rrhcm	112	3	body	body	NN
cord-009417-458rrhcm	112	4	ER	er	NN
cord-009417-458rrhcm	112	5	at	at	IN
cord-009417-458rrhcm	112	6	baseline	baseline	NN
cord-009417-458rrhcm	112	7	is	be	VBZ
cord-009417-458rrhcm	112	8	about	about	RB
cord-009417-458rrhcm	112	9	25	25	CD
cord-009417-458rrhcm	112	10	%	%	NN
cord-009417-458rrhcm	112	11	.	.	.
cord-009417-458rrhcm	113	1	A	a	DT
cord-009417-458rrhcm	113	2	falling	fall	VBG
cord-009417-458rrhcm	113	3	Pv	Pv	NNP
cord-009417-458rrhcm	113	4	O	O	NNP
cord-009417-458rrhcm	113	5	2	2	CD
cord-009417-458rrhcm	113	6	and	and	CC
cord-009417-458rrhcm	113	7	an	an	DT
cord-009417-458rrhcm	113	8	ER	er	NN
cord-009417-458rrhcm	113	9	increasing	increase	VBG
cord-009417-458rrhcm	113	10	to	to	IN
cord-009417-458rrhcm	113	11	greater	great	JJR
cord-009417-458rrhcm	113	12	than	than	IN
cord-009417-458rrhcm	113	13	50	50	CD
cord-009417-458rrhcm	113	14	%	%	NN
cord-009417-458rrhcm	113	15	have	have	VBP
cord-009417-458rrhcm	113	16	been	be	VBN
cord-009417-458rrhcm	113	17	proposed	propose	VBN
cord-009417-458rrhcm	113	18	as	as	IN
cord-009417-458rrhcm	113	19	indicators	indicator	NNS
cord-009417-458rrhcm	113	20	of	of	IN
cord-009417-458rrhcm	113	21	the	the	DT
cord-009417-458rrhcm	113	22	need	need	NN
cord-009417-458rrhcm	113	23	for	for	IN
cord-009417-458rrhcm	113	24	red	red	JJ
cord-009417-458rrhcm	113	25	cell	cell	NN
cord-009417-458rrhcm	113	26	transfusion	transfusion	NN
cord-009417-458rrhcm	113	27	.	.	.
cord-009417-458rrhcm	114	1	21	21	CD
cord-009417-458rrhcm	115	1	There	there	EX
cord-009417-458rrhcm	115	2	have	have	VBP
cord-009417-458rrhcm	115	3	been	be	VBN
cord-009417-458rrhcm	115	4	only	only	RB
cord-009417-458rrhcm	115	5	10	10	CD
cord-009417-458rrhcm	115	6	randomized	randomized	JJ
cord-009417-458rrhcm	115	7	trials	trial	NNS
cord-009417-458rrhcm	115	8	of	of	IN
cord-009417-458rrhcm	115	9	transfusion	transfusion	NN
cord-009417-458rrhcm	115	10	policy	policy	NN
cord-009417-458rrhcm	115	11	in	in	IN
cord-009417-458rrhcm	115	12	the	the	DT
cord-009417-458rrhcm	115	13	ICU	ICU	NNP
cord-009417-458rrhcm	115	14	,	,	,
cord-009417-458rrhcm	115	15	and	and	CC
cord-009417-458rrhcm	115	16	only	only	RB
cord-009417-458rrhcm	115	17	1	1	CD
cord-009417-458rrhcm	115	18	of	of	IN
cord-009417-458rrhcm	115	19	them	-PRON-	PRP
cord-009417-458rrhcm	115	20	was	be	VBD
cord-009417-458rrhcm	115	21	large	large	JJ
cord-009417-458rrhcm	115	22	enough	enough	RB
cord-009417-458rrhcm	115	23	to	to	TO
cord-009417-458rrhcm	115	24	draw	draw	VB
cord-009417-458rrhcm	115	25	specifi	specifi	NNP
cord-009417-458rrhcm	115	26	c	c	NN
cord-009417-458rrhcm	115	27	,	,	,
cord-009417-458rrhcm	115	28	statistically	statistically	RB
cord-009417-458rrhcm	115	29	signifi	signifi	NNP
cord-009417-458rrhcm	115	30	ca	can	MD
cord-009417-458rrhcm	115	31	nt	not	RB
cord-009417-458rrhcm	115	32	conclusions	conclusion	NNS
cord-009417-458rrhcm	115	33	.	.	.
cord-009417-458rrhcm	116	1	22	22	CD
cord-009417-458rrhcm	117	1	The	the	DT
cord-009417-458rrhcm	117	2	Canadian	Canadian	NNP
cord-009417-458rrhcm	117	3	Critical	Critical	NNP
cord-009417-458rrhcm	117	4	Care	Care	NNP
cord-009417-458rrhcm	117	5	Trials	Trials	NNPS
cord-009417-458rrhcm	117	6	Group	Group	NNP
cord-009417-458rrhcm	117	7	compared	compare	VBD
cord-009417-458rrhcm	117	8	a	a	DT
cord-009417-458rrhcm	117	9	liberal	liberal	JJ
cord-009417-458rrhcm	117	10	(	(	-LRB-
cord-009417-458rrhcm	117	11	target	target	NN
cord-009417-458rrhcm	117	12	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	117	13	,	,	,
cord-009417-458rrhcm	117	14	10	10	CD
cord-009417-458rrhcm	117	15	to	to	TO
cord-009417-458rrhcm	117	16	12	12	CD
cord-009417-458rrhcm	117	17	g	g	NN
cord-009417-458rrhcm	117	18	/	/	SYM
cord-009417-458rrhcm	117	19	dL	dl	NN
cord-009417-458rrhcm	117	20	)	)	-RRB-
cord-009417-458rrhcm	117	21	with	with	IN
cord-009417-458rrhcm	117	22	a	a	DT
cord-009417-458rrhcm	117	23	restrictive	restrictive	JJ
cord-009417-458rrhcm	117	24	(	(	-LRB-
cord-009417-458rrhcm	117	25	target	target	NN
cord-009417-458rrhcm	117	26	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	117	27	,	,	,
cord-009417-458rrhcm	117	28	7	7	CD
cord-009417-458rrhcm	117	29	to	to	TO
cord-009417-458rrhcm	117	30	9	9	CD
cord-009417-458rrhcm	117	31	g	g	NN
cord-009417-458rrhcm	117	32	/	/	SYM
cord-009417-458rrhcm	117	33	dL	dl	NN
cord-009417-458rrhcm	117	34	)	)	-RRB-
cord-009417-458rrhcm	117	35	red	red	JJ
cord-009417-458rrhcm	117	36	cell	cell	NN
cord-009417-458rrhcm	117	37	transfusion	transfusion	NN
cord-009417-458rrhcm	117	38	policy	policy	NN
cord-009417-458rrhcm	117	39	in	in	IN
cord-009417-458rrhcm	117	40	patients	patient	NNS
cord-009417-458rrhcm	117	41	stratifi	stratifi	NNP
cord-009417-458rrhcm	117	42	ed	ed	NN
cord-009417-458rrhcm	117	43	for	for	IN
cord-009417-458rrhcm	117	44	disease	disease	NN
cord-009417-458rrhcm	117	45	severity	severity	NN
cord-009417-458rrhcm	117	46	.	.	.
cord-009417-458rrhcm	118	1	At	at	IN
cord-009417-458rrhcm	118	2	30	30	CD
cord-009417-458rrhcm	118	3	days	day	NNS
cord-009417-458rrhcm	118	4	from	from	IN
cord-009417-458rrhcm	118	5	randomization	randomization	NN
cord-009417-458rrhcm	118	6	,	,	,
cord-009417-458rrhcm	118	7	the	the	DT
cord-009417-458rrhcm	118	8	restrictive	restrictive	JJ
cord-009417-458rrhcm	118	9	strategy	strategy	NN
cord-009417-458rrhcm	118	10	was	be	VBD
cord-009417-458rrhcm	118	11	at	at	IN
cord-009417-458rrhcm	118	12	least	least	JJS
cord-009417-458rrhcm	118	13	as	as	RB
cord-009417-458rrhcm	118	14	good	good	JJ
cord-009417-458rrhcm	118	15	as	as	IN
cord-009417-458rrhcm	118	16	,	,	,
cord-009417-458rrhcm	118	17	if	if	IN
cord-009417-458rrhcm	118	18	not	not	RB
cord-009417-458rrhcm	118	19	better	well	JJR
cord-009417-458rrhcm	118	20	than	than	IN
cord-009417-458rrhcm	118	21	(	(	-LRB-
cord-009417-458rrhcm	118	22	P	p	NN
cord-009417-458rrhcm	118	23	=	=	SYM
cord-009417-458rrhcm	118	24	.11	.11	.
cord-009417-458rrhcm	118	25	)	)	-RRB-
cord-009417-458rrhcm	119	1	the	the	DT
cord-009417-458rrhcm	119	2	liberal	liberal	JJ
cord-009417-458rrhcm	119	3	strategy	strategy	NN
cord-009417-458rrhcm	119	4	,	,	,
cord-009417-458rrhcm	119	5	and	and	CC
cord-009417-458rrhcm	119	6	overall	overall	JJ
cord-009417-458rrhcm	119	7	hospital	hospital	NN
cord-009417-458rrhcm	119	8	mortality	mortality	NN
cord-009417-458rrhcm	119	9	was	be	VBD
cord-009417-458rrhcm	119	10	signifi	signifi	NNP
cord-009417-458rrhcm	119	11	cantly	cantly	RB
cord-009417-458rrhcm	119	12	lower	lower	RBR
cord-009417-458rrhcm	119	13	in	in	IN
cord-009417-458rrhcm	119	14	the	the	DT
cord-009417-458rrhcm	119	15	restrictive	restrictive	JJ
cord-009417-458rrhcm	119	16	strategy	strategy	NN
cord-009417-458rrhcm	119	17	group	group	NN
cord-009417-458rrhcm	119	18	(	(	-LRB-
cord-009417-458rrhcm	119	19	P	p	NN
cord-009417-458rrhcm	119	20	=	=	SYM
cord-009417-458rrhcm	119	21	.05	.05	NN
cord-009417-458rrhcm	119	22	)	)	-RRB-
cord-009417-458rrhcm	119	23	.	.	.
cord-009417-458rrhcm	120	1	For	for	IN
cord-009417-458rrhcm	120	2	patients	patient	NNS
cord-009417-458rrhcm	120	3	younger	young	JJR
cord-009417-458rrhcm	120	4	than	than	IN
cord-009417-458rrhcm	120	5	55	55	CD
cord-009417-458rrhcm	120	6	years	year	NNS
cord-009417-458rrhcm	120	7	and	and	CC
cord-009417-458rrhcm	120	8	for	for	IN
cord-009417-458rrhcm	120	9	patients	patient	NNS
cord-009417-458rrhcm	120	10	with	with	IN
cord-009417-458rrhcm	120	11	lower	low	JJR
cord-009417-458rrhcm	120	12	(	(	-LRB-
cord-009417-458rrhcm	120	13	<	<	XX
cord-009417-458rrhcm	120	14	20	20	CD
cord-009417-458rrhcm	120	15	)	)	-RRB-
cord-009417-458rrhcm	120	16	APACHE	APACHE	NNP
cord-009417-458rrhcm	120	17	(	(	-LRB-
cord-009417-458rrhcm	120	18	Acute	Acute	NNP
cord-009417-458rrhcm	120	19	Physiology	Physiology	NNP
cord-009417-458rrhcm	120	20	,	,	,
cord-009417-458rrhcm	120	21	Age	Age	NNP
cord-009417-458rrhcm	120	22	,	,	,
cord-009417-458rrhcm	120	23	and	and	CC
cord-009417-458rrhcm	120	24	Chronic	Chronic	NNP
cord-009417-458rrhcm	120	25	Health	Health	NNP
cord-009417-458rrhcm	120	26	Evaluation	Evaluation	NNP
cord-009417-458rrhcm	120	27	)	)	-RRB-
cord-009417-458rrhcm	121	1	II	II	NNP
cord-009417-458rrhcm	121	2	scores	score	NNS
cord-009417-458rrhcm	121	3	,	,	,
cord-009417-458rrhcm	121	4	the	the	DT
cord-009417-458rrhcm	121	5	restrictive	restrictive	JJ
cord-009417-458rrhcm	121	6	strategy	strategy	NN
cord-009417-458rrhcm	121	7	was	be	VBD
cord-009417-458rrhcm	121	8	clearly	clearly	RB
cord-009417-458rrhcm	121	9	superior	superior	JJ
cord-009417-458rrhcm	121	10	.	.	.
cord-009417-458rrhcm	122	1	In	in	IN
cord-009417-458rrhcm	122	2	addition	addition	NN
cord-009417-458rrhcm	122	3	,	,	,
cord-009417-458rrhcm	122	4	liberal	liberal	JJ
cord-009417-458rrhcm	122	5	transfusion	transfusion	NN
cord-009417-458rrhcm	122	6	was	be	VBD
cord-009417-458rrhcm	122	7	not	not	RB
cord-009417-458rrhcm	122	8	associated	associate	VBN
cord-009417-458rrhcm	122	9	with	with	IN
cord-009417-458rrhcm	122	10	shorter	short	JJR
cord-009417-458rrhcm	122	11	ICU	ICU	NNP
cord-009417-458rrhcm	122	12	stays	stay	VBZ
cord-009417-458rrhcm	122	13	,	,	,
cord-009417-458rrhcm	122	14	less	less	JJR
cord-009417-458rrhcm	122	15	organ	organ	NN
cord-009417-458rrhcm	122	16	failure	failure	NN
cord-009417-458rrhcm	122	17	,	,	,
cord-009417-458rrhcm	122	18	or	or	CC
cord-009417-458rrhcm	122	19	shorter	short	JJR
cord-009417-458rrhcm	122	20	hospital	hospital	NN
cord-009417-458rrhcm	122	21	stays	stay	NNS
cord-009417-458rrhcm	122	22	;	;	:
cord-009417-458rrhcm	122	23	longer	long	JJR
cord-009417-458rrhcm	122	24	mechanical	mechanical	JJ
cord-009417-458rrhcm	122	25	ventilation	ventilation	NN
cord-009417-458rrhcm	122	26	times	time	NNS
cord-009417-458rrhcm	122	27	and	and	CC
cord-009417-458rrhcm	122	28	cardiac	cardiac	JJ
cord-009417-458rrhcm	122	29	events	event	NNS
cord-009417-458rrhcm	122	30	were	be	VBD
cord-009417-458rrhcm	122	31	more	more	RBR
cord-009417-458rrhcm	122	32	frequent	frequent	JJ
cord-009417-458rrhcm	122	33	in	in	IN
cord-009417-458rrhcm	122	34	the	the	DT
cord-009417-458rrhcm	122	35	liberal	liberal	JJ
cord-009417-458rrhcm	122	36	strategy	strategy	NN
cord-009417-458rrhcm	122	37	group	group	NN
cord-009417-458rrhcm	122	38	.	.	.
cord-009417-458rrhcm	123	1	A	a	DT
cord-009417-458rrhcm	123	2	later	later	JJ
cord-009417-458rrhcm	123	3	subgroup	subgroup	NN
cord-009417-458rrhcm	123	4	analysis	analysis	NN
cord-009417-458rrhcm	123	5	of	of	IN
cord-009417-458rrhcm	123	6	patients	patient	NNS
cord-009417-458rrhcm	123	7	with	with	IN
cord-009417-458rrhcm	123	8	cardiovascular	cardiovascular	JJ
cord-009417-458rrhcm	123	9	disease	disease	NN
cord-009417-458rrhcm	123	10	,	,	,
cord-009417-458rrhcm	123	11	though	though	IN
cord-009417-458rrhcm	123	12	small	small	JJ
cord-009417-458rrhcm	123	13	enough	enough	RB
cord-009417-458rrhcm	123	14	to	to	TO
cord-009417-458rrhcm	123	15	have	have	VB
cord-009417-458rrhcm	123	16	statistical	statistical	JJ
cord-009417-458rrhcm	123	17	doubt	doubt	NN
cord-009417-458rrhcm	123	18	,	,	,
cord-009417-458rrhcm	123	19	suggested	suggest	VBD
cord-009417-458rrhcm	123	20	that	that	IN
cord-009417-458rrhcm	123	21	a	a	DT
cord-009417-458rrhcm	123	22	more	more	RBR
cord-009417-458rrhcm	123	23	liberal	liberal	JJ
cord-009417-458rrhcm	123	24	transfusion	transfusion	NN
cord-009417-458rrhcm	123	25	strategy	strategy	NN
cord-009417-458rrhcm	123	26	was	be	VBD
cord-009417-458rrhcm	123	27	probably	probably	RB
cord-009417-458rrhcm	123	28	appropriate	appropriate	JJ
cord-009417-458rrhcm	123	29	for	for	IN
cord-009417-458rrhcm	123	30	patients	patient	NNS
cord-009417-458rrhcm	123	31	with	with	IN
cord-009417-458rrhcm	123	32	severe	severe	JJ
cord-009417-458rrhcm	123	33	ischemic	ischemic	JJ
cord-009417-458rrhcm	123	34	coronary	coronary	JJ
cord-009417-458rrhcm	123	35	disease	disease	NN
cord-009417-458rrhcm	123	36	.	.	.
cord-009417-458rrhcm	124	1	23	23	CD
cord-009417-458rrhcm	125	1	This	this	DT
cord-009417-458rrhcm	125	2	observation	observation	NN
cord-009417-458rrhcm	125	3	has	have	VBZ
cord-009417-458rrhcm	125	4	some	some	DT
cord-009417-458rrhcm	125	5	support	support	NN
cord-009417-458rrhcm	125	6	in	in	IN
cord-009417-458rrhcm	125	7	experimental	experimental	JJ
cord-009417-458rrhcm	125	8	studies	study	NNS
cord-009417-458rrhcm	125	9	of	of	IN
cord-009417-458rrhcm	125	10	the	the	DT
cord-009417-458rrhcm	125	11	effects	effect	NNS
cord-009417-458rrhcm	125	12	of	of	IN
cord-009417-458rrhcm	125	13	anemia	anemia	NN
cord-009417-458rrhcm	125	14	in	in	IN
cord-009417-458rrhcm	125	15	laboratory	laboratory	NN
cord-009417-458rrhcm	125	16	animals	animal	NNS
cord-009417-458rrhcm	125	17	with	with	IN
cord-009417-458rrhcm	125	18	coronary	coronary	JJ
cord-009417-458rrhcm	125	19	occlusion	occlusion	NN
cord-009417-458rrhcm	125	20	.	.	.
cord-009417-458rrhcm	126	1	24	24	CD
cord-009417-458rrhcm	127	1	The	the	DT
cord-009417-458rrhcm	127	2	Canadian	canadian	JJ
cord-009417-458rrhcm	127	3	study	study	NN
cord-009417-458rrhcm	127	4	has	have	VBZ
cord-009417-458rrhcm	127	5	highlighted	highlight	VBN
cord-009417-458rrhcm	127	6	the	the	DT
cord-009417-458rrhcm	127	7	many	many	JJ
cord-009417-458rrhcm	127	8	and	and	CC
cord-009417-458rrhcm	127	9	complex	complex	JJ
cord-009417-458rrhcm	127	10	issues	issue	NNS
cord-009417-458rrhcm	127	11	involved	involve	VBN
cord-009417-458rrhcm	127	12	in	in	IN
cord-009417-458rrhcm	127	13	transfusion	transfusion	NN
cord-009417-458rrhcm	127	14	decision	decision	NN
cord-009417-458rrhcm	127	15	making	make	VBG
cord-009417-458rrhcm	127	16	in	in	IN
cord-009417-458rrhcm	127	17	the	the	DT
cord-009417-458rrhcm	127	18	ICU	ICU	NNP
cord-009417-458rrhcm	127	19	.	.	.
cord-009417-458rrhcm	128	1	Since	since	IN
cord-009417-458rrhcm	128	2	publication	publication	NN
cord-009417-458rrhcm	128	3	of	of	IN
cord-009417-458rrhcm	128	4	the	the	DT
cord-009417-458rrhcm	128	5	Canadian	canadian	JJ
cord-009417-458rrhcm	128	6	study	study	NN
cord-009417-458rrhcm	128	7	,	,	,
cord-009417-458rrhcm	128	8	several	several	JJ
cord-009417-458rrhcm	128	9	large	large	JJ
cord-009417-458rrhcm	128	10	reports	report	NNS
cord-009417-458rrhcm	128	11	have	have	VBP
cord-009417-458rrhcm	128	12	examined	examine	VBN
cord-009417-458rrhcm	128	13	the	the	DT
cord-009417-458rrhcm	128	14	use	use	NN
cord-009417-458rrhcm	128	15	of	of	IN
cord-009417-458rrhcm	128	16	red	red	JJ
cord-009417-458rrhcm	128	17	cell	cell	NN
cord-009417-458rrhcm	128	18	transfusions	transfusion	NNS
cord-009417-458rrhcm	128	19	in	in	IN
cord-009417-458rrhcm	128	20	critical	critical	JJ
cord-009417-458rrhcm	128	21	care	care	NN
cord-009417-458rrhcm	128	22	units	unit	NNS
cord-009417-458rrhcm	128	23	.	.	.
cord-009417-458rrhcm	129	1	Vincent	Vincent	NNP
cord-009417-458rrhcm	129	2	and	and	CC
cord-009417-458rrhcm	129	3	colleagues	colleague	NNS
cord-009417-458rrhcm	129	4	25	25	CD
cord-009417-458rrhcm	129	5	surveyed	survey	VBN
cord-009417-458rrhcm	129	6	European	european	JJ
cord-009417-458rrhcm	129	7	ICUs	icu	NNS
cord-009417-458rrhcm	129	8	and	and	CC
cord-009417-458rrhcm	129	9	found	find	VBD
cord-009417-458rrhcm	129	10	that	that	IN
cord-009417-458rrhcm	129	11	the	the	DT
cord-009417-458rrhcm	129	12	transfusion	transfusion	NN
cord-009417-458rrhcm	129	13	rate	rate	NN
cord-009417-458rrhcm	129	14	in	in	IN
cord-009417-458rrhcm	129	15	3534	3534	CD
cord-009417-458rrhcm	129	16	patients	patient	NNS
cord-009417-458rrhcm	129	17	was	be	VBD
cord-009417-458rrhcm	129	18	37	37	CD
cord-009417-458rrhcm	129	19	%	%	NN
cord-009417-458rrhcm	129	20	during	during	IN
cord-009417-458rrhcm	129	21	the	the	DT
cord-009417-458rrhcm	129	22	ICU	ICU	NNP
cord-009417-458rrhcm	129	23	stay	stay	NN
cord-009417-458rrhcm	129	24	and	and	CC
cord-009417-458rrhcm	129	25	12.7	12.7	CD
cord-009417-458rrhcm	129	26	%	%	NN
cord-009417-458rrhcm	129	27	after	after	IN
cord-009417-458rrhcm	129	28	the	the	DT
cord-009417-458rrhcm	129	29	stay	stay	NN
cord-009417-458rrhcm	129	30	.	.	.
cord-009417-458rrhcm	130	1	The	the	DT
cord-009417-458rrhcm	130	2	mean	mean	JJ
cord-009417-458rrhcm	130	3	pretransfusion	pretransfusion	NN
cord-009417-458rrhcm	130	4	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	130	5	level	level	NN
cord-009417-458rrhcm	130	6	was	be	VBD
cord-009417-458rrhcm	130	7	8.4	8.4	CD
cord-009417-458rrhcm	130	8	g/	g/	NNS
cord-009417-458rrhcm	131	1	dL.	dL.	NNP
cord-009417-458rrhcm	131	2	Corwin	Corwin	NNP
cord-009417-458rrhcm	131	3	and	and	CC
cord-009417-458rrhcm	131	4	colleagues	colleague	NNS
cord-009417-458rrhcm	131	5	26	26	CD
cord-009417-458rrhcm	131	6	studied	study	VBD
cord-009417-458rrhcm	131	7	284	284	CD
cord-009417-458rrhcm	131	8	ICUs	icu	NNS
cord-009417-458rrhcm	131	9	in	in	IN
cord-009417-458rrhcm	131	10	the	the	DT
cord-009417-458rrhcm	131	11	United	United	NNP
cord-009417-458rrhcm	131	12	States	States	NNP
cord-009417-458rrhcm	131	13	a	a	DT
cord-009417-458rrhcm	131	14	year	year	NN
cord-009417-458rrhcm	131	15	later	later	RB
cord-009417-458rrhcm	131	16	and	and	CC
cord-009417-458rrhcm	131	17	found	find	VBD
cord-009417-458rrhcm	131	18	great	great	JJ
cord-009417-458rrhcm	131	19	similarity	similarity	NN
cord-009417-458rrhcm	131	20	:	:	:
cord-009417-458rrhcm	131	21	nearly	nearly	RB
cord-009417-458rrhcm	131	22	50	50	CD
cord-009417-458rrhcm	131	23	%	%	NN
cord-009417-458rrhcm	131	24	of	of	IN
cord-009417-458rrhcm	131	25	patients	patient	NNS
cord-009417-458rrhcm	131	26	received	receive	VBD
cord-009417-458rrhcm	131	27	transfusions	transfusion	NNS
cord-009417-458rrhcm	131	28	,	,	,
cord-009417-458rrhcm	131	29	and	and	CC
cord-009417-458rrhcm	131	30	the	the	DT
cord-009417-458rrhcm	131	31	mean	mean	JJ
cord-009417-458rrhcm	131	32	threshold	threshold	NN
cord-009417-458rrhcm	131	33	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	131	34	level	level	NN
cord-009417-458rrhcm	131	35	was	be	VBD
cord-009417-458rrhcm	131	36	8.6	8.6	CD
cord-009417-458rrhcm	131	37	g	g	NN
cord-009417-458rrhcm	131	38	/	/	SYM
cord-009417-458rrhcm	131	39	dL.	dl.	NN
cord-009417-458rrhcm	132	1	A	a	DT
cord-009417-458rrhcm	132	2	single	single	JJ
cord-009417-458rrhcm	132	3	large	large	JJ
cord-009417-458rrhcm	132	4	Scottish	scottish	JJ
cord-009417-458rrhcm	132	5	teaching	teaching	NN
cord-009417-458rrhcm	132	6	hospital	hospital	NN
cord-009417-458rrhcm	132	7	reported	report	VBD
cord-009417-458rrhcm	132	8	a	a	DT
cord-009417-458rrhcm	132	9	more	more	RBR
cord-009417-458rrhcm	132	10	parsimonious	parsimonious	JJ
cord-009417-458rrhcm	132	11	practice	practice	NN
cord-009417-458rrhcm	132	12	:	:	:
cord-009417-458rrhcm	132	13	the	the	DT
cord-009417-458rrhcm	132	14	rate	rate	NN
cord-009417-458rrhcm	132	15	of	of	IN
cord-009417-458rrhcm	132	16	transfusion	transfusion	NN
cord-009417-458rrhcm	132	17	was	be	VBD
cord-009417-458rrhcm	132	18	still	still	RB
cord-009417-458rrhcm	132	19	52	52	CD
cord-009417-458rrhcm	132	20	%	%	NN
cord-009417-458rrhcm	132	21	in	in	IN
cord-009417-458rrhcm	132	22	its	-PRON-	PRP$
cord-009417-458rrhcm	132	23	ICU	ICU	NNP
cord-009417-458rrhcm	132	24	patients	patient	NNS
cord-009417-458rrhcm	132	25	,	,	,
cord-009417-458rrhcm	132	26	but	but	CC
cord-009417-458rrhcm	132	27	the	the	DT
cord-009417-458rrhcm	132	28	total	total	JJ
cord-009417-458rrhcm	132	29	volume	volume	NN
cord-009417-458rrhcm	132	30	of	of	IN
cord-009417-458rrhcm	132	31	blood	blood	NN
cord-009417-458rrhcm	132	32	used	use	VBN
cord-009417-458rrhcm	132	33	was	be	VBD
cord-009417-458rrhcm	132	34	slightly	slightly	RB
cord-009417-458rrhcm	132	35	smaller	small	JJR
cord-009417-458rrhcm	132	36	and	and	CC
cord-009417-458rrhcm	132	37	the	the	DT
cord-009417-458rrhcm	132	38	mean	mean	JJ
cord-009417-458rrhcm	132	39	pretransfusion	pretransfusion	NNP
cord-009417-458rrhcm	132	40	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	132	41	level	level	NN
cord-009417-458rrhcm	132	42	was	be	VBD
cord-009417-458rrhcm	132	43	only	only	RB
cord-009417-458rrhcm	132	44	7.8	7.8	CD
cord-009417-458rrhcm	132	45	g	g	NN
cord-009417-458rrhcm	132	46	/	/	SYM
cord-009417-458rrhcm	132	47	dL.	dl.	NN
cord-009417-458rrhcm	132	48	27	27	CD
cord-009417-458rrhcm	133	1	All	all	PDT
cord-009417-458rrhcm	133	2	these	these	DT
cord-009417-458rrhcm	133	3	authors	author	NNS
cord-009417-458rrhcm	133	4	have	have	VBP
cord-009417-458rrhcm	133	5	concluded	conclude	VBN
cord-009417-458rrhcm	133	6	that	that	IN
cord-009417-458rrhcm	133	7	ICU	ICU	NNP
cord-009417-458rrhcm	133	8	practice	practice	NN
cord-009417-458rrhcm	133	9	has	have	VBZ
cord-009417-458rrhcm	133	10	not	not	RB
cord-009417-458rrhcm	133	11	fully	fully	RB
cord-009417-458rrhcm	133	12	embraced	embrace	VBN
cord-009417-458rrhcm	133	13	the	the	DT
cord-009417-458rrhcm	133	14	guidelines	guideline	NNS
cord-009417-458rrhcm	133	15	of	of	IN
cord-009417-458rrhcm	133	16	the	the	DT
cord-009417-458rrhcm	133	17	Canadian	canadian	JJ
cord-009417-458rrhcm	133	18	clinical	clinical	JJ
cord-009417-458rrhcm	133	19	trial	trial	NN
cord-009417-458rrhcm	133	20	.	.	.
cord-009417-458rrhcm	134	1	In	in	IN
cord-009417-458rrhcm	134	2	contrast	contrast	NN
cord-009417-458rrhcm	134	3	,	,	,
cord-009417-458rrhcm	134	4	18	18	CD
cord-009417-458rrhcm	134	5	hospitals	hospital	NNS
cord-009417-458rrhcm	134	6	in	in	IN
cord-009417-458rrhcm	134	7	Australia	Australia	NNP
cord-009417-458rrhcm	134	8	and	and	CC
cord-009417-458rrhcm	134	9	New	New	NNP
cord-009417-458rrhcm	134	10	Zealand	Zealand	NNP
cord-009417-458rrhcm	134	11	have	have	VBP
cord-009417-458rrhcm	134	12	reported	report	VBN
cord-009417-458rrhcm	134	13	on	on	IN
cord-009417-458rrhcm	134	14	transfusion	transfusion	NN
cord-009417-458rrhcm	134	15	in	in	IN
cord-009417-458rrhcm	134	16	1808	1808	CD
cord-009417-458rrhcm	134	17	consecutive	consecutive	JJ
cord-009417-458rrhcm	134	18	ICU	ICU	NNP
cord-009417-458rrhcm	134	19	admissions	admission	NNS
cord-009417-458rrhcm	134	20	,	,	,
cord-009417-458rrhcm	134	21	and	and	CC
cord-009417-458rrhcm	134	22	although	although	IN
cord-009417-458rrhcm	134	23	the	the	DT
cord-009417-458rrhcm	134	24	authors	author	NNS
cord-009417-458rrhcm	134	25	found	find	VBD
cord-009417-458rrhcm	134	26	a	a	DT
cord-009417-458rrhcm	134	27	median	median	JJ
cord-009417-458rrhcm	134	28	pretransfusion	pretransfusion	NN
cord-009417-458rrhcm	134	29	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	134	30	concentration	concentration	NN
cord-009417-458rrhcm	134	31	of	of	IN
cord-009417-458rrhcm	134	32	8.2	8.2	CD
cord-009417-458rrhcm	134	33	g	g	NN
cord-009417-458rrhcm	134	34	/	/	SYM
cord-009417-458rrhcm	134	35	dL	dl	NN
cord-009417-458rrhcm	134	36	,	,	,
cord-009417-458rrhcm	134	37	the	the	DT
cord-009417-458rrhcm	134	38	rate	rate	NN
cord-009417-458rrhcm	134	39	of	of	IN
cord-009417-458rrhcm	134	40	transfusion	transfusion	NN
cord-009417-458rrhcm	134	41	was	be	VBD
cord-009417-458rrhcm	134	42	lower	low	JJR
cord-009417-458rrhcm	134	43	,	,	,
cord-009417-458rrhcm	134	44	at	at	IN
cord-009417-458rrhcm	134	45	only	only	RB
cord-009417-458rrhcm	134	46	19.7	19.7	CD
cord-009417-458rrhcm	134	47	%	%	NN
cord-009417-458rrhcm	134	48	of	of	IN
cord-009417-458rrhcm	134	49	patients	patient	NNS
cord-009417-458rrhcm	134	50	,	,	,
cord-009417-458rrhcm	134	51	60	60	CD
cord-009417-458rrhcm	134	52	%	%	NN
cord-009417-458rrhcm	134	53	of	of	IN
cord-009417-458rrhcm	134	54	whom	whom	WP
cord-009417-458rrhcm	134	55	were	be	VBD
cord-009417-458rrhcm	134	56	bleeding	bleed	VBG
cord-009417-458rrhcm	134	57	.	.	.
cord-009417-458rrhcm	135	1	28	28	CD
cord-009417-458rrhcm	136	1	The	the	DT
cord-009417-458rrhcm	136	2	"	"	``
cord-009417-458rrhcm	136	3	inappropriate	inappropriate	JJ
cord-009417-458rrhcm	136	4	"	"	''
cord-009417-458rrhcm	136	5	transfusion	transfusion	NN
cord-009417-458rrhcm	136	6	rate	rate	NN
cord-009417-458rrhcm	136	7	was	be	VBD
cord-009417-458rrhcm	136	8	3	3	CD
cord-009417-458rrhcm	136	9	%	%	NN
cord-009417-458rrhcm	136	10	.	.	.
cord-009417-458rrhcm	137	1	The	the	DT
cord-009417-458rrhcm	137	2	authors	author	NNS
cord-009417-458rrhcm	137	3	speculate	speculate	VBP
cord-009417-458rrhcm	137	4	that	that	IN
cord-009417-458rrhcm	137	5	the	the	DT
cord-009417-458rrhcm	137	6	practitioners	practitioner	NNS
cord-009417-458rrhcm	137	7	may	may	MD
cord-009417-458rrhcm	137	8	have	have	VB
cord-009417-458rrhcm	137	9	been	be	VBN
cord-009417-458rrhcm	137	10	infl	infl	VBN
cord-009417-458rrhcm	137	11	uenced	uence	VBN
cord-009417-458rrhcm	137	12	by	by	IN
cord-009417-458rrhcm	137	13	publication	publication	NN
cord-009417-458rrhcm	137	14	of	of	IN
cord-009417-458rrhcm	137	15	the	the	DT
cord-009417-458rrhcm	137	16	Canadian	canadian	JJ
cord-009417-458rrhcm	137	17	study	study	NN
cord-009417-458rrhcm	137	18	and	and	CC
cord-009417-458rrhcm	137	19	their	-PRON-	PRP$
cord-009417-458rrhcm	137	20	own	own	JJ
cord-009417-458rrhcm	137	21	regional	regional	JJ
cord-009417-458rrhcm	137	22	survey	survey	NN
cord-009417-458rrhcm	137	23	of	of	IN
cord-009417-458rrhcm	137	24	transfusion	transfusion	NN
cord-009417-458rrhcm	137	25	practices	practice	NNS
cord-009417-458rrhcm	137	26	.	.	.
cord-009417-458rrhcm	138	1	Nonetheless	nonetheless	RB
cord-009417-458rrhcm	138	2	,	,	,
cord-009417-458rrhcm	138	3	they	-PRON-	PRP
cord-009417-458rrhcm	138	4	agree	agree	VBP
cord-009417-458rrhcm	138	5	that	that	IN
cord-009417-458rrhcm	138	6	full	full	JJ
cord-009417-458rrhcm	138	7	implementation	implementation	NN
cord-009417-458rrhcm	138	8	of	of	IN
cord-009417-458rrhcm	138	9	the	the	DT
cord-009417-458rrhcm	138	10	Canadian	canadian	JJ
cord-009417-458rrhcm	138	11	guidelines	guideline	NNS
cord-009417-458rrhcm	138	12	in	in	IN
cord-009417-458rrhcm	138	13	their	-PRON-	PRP$
cord-009417-458rrhcm	138	14	clinical	clinical	JJ
cord-009417-458rrhcm	138	15	setting	setting	NN
cord-009417-458rrhcm	138	16	might	may	MD
cord-009417-458rrhcm	138	17	be	be	VB
cord-009417-458rrhcm	138	18	controversial	controversial	JJ
cord-009417-458rrhcm	138	19	.	.	.
cord-009417-458rrhcm	139	1	The	the	DT
cord-009417-458rrhcm	139	2	literature	literature	NN
cord-009417-458rrhcm	139	3	on	on	IN
cord-009417-458rrhcm	139	4	RBC	RBC	NNP
cord-009417-458rrhcm	139	5	transfusion	transfusion	NN
cord-009417-458rrhcm	139	6	in	in	IN
cord-009417-458rrhcm	139	7	the	the	DT
cord-009417-458rrhcm	139	8	setting	setting	NN
cord-009417-458rrhcm	139	9	of	of	IN
cord-009417-458rrhcm	139	10	surgery	surgery	NN
cord-009417-458rrhcm	139	11	,	,	,
cord-009417-458rrhcm	139	12	particularly	particularly	RB
cord-009417-458rrhcm	139	13	surgery	surgery	NN
cord-009417-458rrhcm	139	14	with	with	IN
cord-009417-458rrhcm	139	15	the	the	DT
cord-009417-458rrhcm	139	16	use	use	NN
cord-009417-458rrhcm	139	17	of	of	IN
cord-009417-458rrhcm	139	18	blood	blood	NN
cord-009417-458rrhcm	139	19	products	product	NNS
cord-009417-458rrhcm	139	20	,	,	,
cord-009417-458rrhcm	139	21	is	be	VBZ
cord-009417-458rrhcm	139	22	growing	grow	VBG
cord-009417-458rrhcm	139	23	.	.	.
cord-009417-458rrhcm	140	1	A	a	DT
cord-009417-458rrhcm	140	2	mounting	mount	VBG
cord-009417-458rrhcm	140	3	body	body	NN
cord-009417-458rrhcm	140	4	of	of	IN
cord-009417-458rrhcm	140	5	data	datum	NNS
cord-009417-458rrhcm	140	6	illustrate	illustrate	VBP
cord-009417-458rrhcm	140	7	the	the	DT
cord-009417-458rrhcm	140	8	human	human	JJ
cord-009417-458rrhcm	140	9	tolerance	tolerance	NN
cord-009417-458rrhcm	140	10	of	of	IN
cord-009417-458rrhcm	140	11	a	a	DT
cord-009417-458rrhcm	140	12	low	low	JJ
cord-009417-458rrhcm	140	13	Hct	Hct	NNP
cord-009417-458rrhcm	140	14	during	during	IN
cord-009417-458rrhcm	140	15	and	and	CC
cord-009417-458rrhcm	140	16	after	after	IN
cord-009417-458rrhcm	140	17	surgery	surgery	NN
cord-009417-458rrhcm	140	18	.	.	.
cord-009417-458rrhcm	141	1	A	a	DT
cord-009417-458rrhcm	141	2	recent	recent	JJ
cord-009417-458rrhcm	141	3	randomized	randomized	JJ
cord-009417-458rrhcm	141	4	trial	trial	NN
cord-009417-458rrhcm	141	5	of	of	IN
cord-009417-458rrhcm	141	6	RBC	RBC	NNP
cord-009417-458rrhcm	141	7	transfusion	transfusion	NN
cord-009417-458rrhcm	141	8	strategy	strategy	NN
cord-009417-458rrhcm	141	9	in	in	IN
cord-009417-458rrhcm	141	10	orthopedic	orthopedic	NN
cord-009417-458rrhcm	141	11	surgery	surgery	NN
cord-009417-458rrhcm	141	12	demonstrated	demonstrate	VBD
cord-009417-458rrhcm	141	13	no	no	DT
cord-009417-458rrhcm	141	14	signifi	signifi	NN
cord-009417-458rrhcm	141	15	ca	can	MD
cord-009417-458rrhcm	141	16	nt	not	RB
cord-009417-458rrhcm	141	17	differences	difference	NNS
cord-009417-458rrhcm	141	18	in	in	IN
cord-009417-458rrhcm	141	19	outcome	outcome	NN
cord-009417-458rrhcm	141	20	between	between	IN
cord-009417-458rrhcm	141	21	a	a	DT
cord-009417-458rrhcm	141	22	restrictive	restrictive	JJ
cord-009417-458rrhcm	141	23	(	(	-LRB-
cord-009417-458rrhcm	141	24	8	8	CD
cord-009417-458rrhcm	141	25	g	g	NN
cord-009417-458rrhcm	141	26	/	/	SYM
cord-009417-458rrhcm	141	27	dL	dl	NN
cord-009417-458rrhcm	141	28	)	)	-RRB-
cord-009417-458rrhcm	141	29	and	and	CC
cord-009417-458rrhcm	141	30	a	a	DT
cord-009417-458rrhcm	141	31	liberal	liberal	JJ
cord-009417-458rrhcm	141	32	(	(	-LRB-
cord-009417-458rrhcm	141	33	10	10	CD
cord-009417-458rrhcm	141	34	g	g	NN
cord-009417-458rrhcm	141	35	/	/	SYM
cord-009417-458rrhcm	141	36	dL	dl	NN
cord-009417-458rrhcm	141	37	)	)	-RRB-
cord-009417-458rrhcm	141	38	transfusion	transfusion	NN
cord-009417-458rrhcm	141	39	threshold	threshold	NN
cord-009417-458rrhcm	141	40	and	and	CC
cord-009417-458rrhcm	141	41	included	include	VBD
cord-009417-458rrhcm	141	42	monitoring	monitor	VBG
cord-009417-458rrhcm	141	43	for	for	IN
cord-009417-458rrhcm	141	44	silent	silent	JJ
cord-009417-458rrhcm	141	45	myocardial	myocardial	JJ
cord-009417-458rrhcm	141	46	ischemia	ischemia	NN
cord-009417-458rrhcm	141	47	preoperatively	preoperatively	NN
cord-009417-458rrhcm	141	48	and	and	CC
cord-009417-458rrhcm	141	49	postoperatively	postoperatively	RB
cord-009417-458rrhcm	141	50	.	.	.
cord-009417-458rrhcm	142	1	29	29	CD
cord-009417-458rrhcm	143	1	Provided	provide	VBN
cord-009417-458rrhcm	143	2	that	that	IN
cord-009417-458rrhcm	143	3	adequate	adequate	JJ
cord-009417-458rrhcm	143	4	perfusion	perfusion	NN
cord-009417-458rrhcm	143	5	of	of	IN
cord-009417-458rrhcm	143	6	the	the	DT
cord-009417-458rrhcm	143	7	microcirculation	microcirculation	NN
cord-009417-458rrhcm	143	8	is	be	VBZ
cord-009417-458rrhcm	143	9	maintained	maintain	VBN
cord-009417-458rrhcm	143	10	,	,	,
cord-009417-458rrhcm	143	11	purposeful	purposeful	JJ
cord-009417-458rrhcm	143	12	maintenance	maintenance	NN
cord-009417-458rrhcm	143	13	of	of	IN
cord-009417-458rrhcm	143	14	a	a	DT
cord-009417-458rrhcm	143	15	low	low	JJ
cord-009417-458rrhcm	143	16	Hct	Hct	NNP
cord-009417-458rrhcm	143	17	during	during	IN
cord-009417-458rrhcm	143	18	surgery	surgery	NN
cord-009417-458rrhcm	143	19	,	,	,
cord-009417-458rrhcm	143	20	a	a	DT
cord-009417-458rrhcm	143	21	technique	technique	NN
cord-009417-458rrhcm	143	22	called	call	VBN
cord-009417-458rrhcm	143	23	normovolemic	normovolemic	NNP
cord-009417-458rrhcm	143	24	hemodilution	hemodilution	NNP
cord-009417-458rrhcm	143	25	,	,	,
cord-009417-458rrhcm	143	26	30	30	CD
cord-009417-458rrhcm	143	27	can	can	MD
cord-009417-458rrhcm	143	28	be	be	VB
cord-009417-458rrhcm	143	29	a	a	DT
cord-009417-458rrhcm	143	30	powerful	powerful	JJ
cord-009417-458rrhcm	143	31	tool	tool	NN
cord-009417-458rrhcm	143	32	in	in	IN
cord-009417-458rrhcm	143	33	minimizing	minimize	VBG
cord-009417-458rrhcm	143	34	blood	blood	NN
cord-009417-458rrhcm	143	35	loss	loss	NN
cord-009417-458rrhcm	143	36	and	and	CC
cord-009417-458rrhcm	143	37	the	the	DT
cord-009417-458rrhcm	143	38	attendant	attendant	NN
cord-009417-458rrhcm	143	39	need	need	NN
cord-009417-458rrhcm	143	40	for	for	IN
cord-009417-458rrhcm	143	41	red	red	JJ
cord-009417-458rrhcm	143	42	cell	cell	NN
cord-009417-458rrhcm	143	43	transfusion	transfusion	NN
cord-009417-458rrhcm	143	44	.	.	.
cord-009417-458rrhcm	144	1	Table	table	NN
cord-009417-458rrhcm	144	2	80	80	CD
cord-009417-458rrhcm	144	3	-1	-1	NN
cord-009417-458rrhcm	144	4	summarizes	summarize	VBZ
cord-009417-458rrhcm	144	5	guidelines	guideline	NNS
cord-009417-458rrhcm	144	6	proposed	propose	VBN
cord-009417-458rrhcm	144	7	by	by	IN
cord-009417-458rrhcm	144	8	the	the	DT
cord-009417-458rrhcm	144	9	National	National	NNP
cord-009417-458rrhcm	144	10	Institutes	Institutes	NNPS
cord-009417-458rrhcm	144	11	of	of	IN
cord-009417-458rrhcm	144	12	Health	Health	NNP
cord-009417-458rrhcm	144	13	,	,	,
cord-009417-458rrhcm	144	14	31	31	CD
cord-009417-458rrhcm	144	15	the	the	DT
cord-009417-458rrhcm	144	16	American	American	NNP
cord-009417-458rrhcm	144	17	Society	Society	NNP
cord-009417-458rrhcm	144	18	of	of	IN
cord-009417-458rrhcm	144	19	Anesthesiologists	Anesthesiologists	NNPS
cord-009417-458rrhcm	144	20	,	,	,
cord-009417-458rrhcm	144	21	32	32	CD
cord-009417-458rrhcm	144	22	and	and	CC
cord-009417-458rrhcm	144	23	the	the	DT
cord-009417-458rrhcm	144	24	American	American	NNP
cord-009417-458rrhcm	144	25	College	College	NNP
cord-009417-458rrhcm	144	26	of	of	IN
cord-009417-458rrhcm	144	27	Physicians	Physicians	NNPS
cord-009417-458rrhcm	144	28	33	33	CD
cord-009417-458rrhcm	144	29	relative	relative	NN
cord-009417-458rrhcm	144	30	to	to	IN
cord-009417-458rrhcm	144	31	the	the	DT
cord-009417-458rrhcm	144	32	transfusion	transfusion	NN
cord-009417-458rrhcm	144	33	of	of	IN
cord-009417-458rrhcm	144	34	RBCs	rbc	NNS
cord-009417-458rrhcm	144	35	.	.	.
cord-009417-458rrhcm	145	1	These	these	DT
cord-009417-458rrhcm	145	2	guidelines	guideline	NNS
cord-009417-458rrhcm	145	3	have	have	VBP
cord-009417-458rrhcm	145	4	been	be	VBN
cord-009417-458rrhcm	145	5	provided	provide	VBN
cord-009417-458rrhcm	145	6	with	with	IN
cord-009417-458rrhcm	145	7	the	the	DT
cord-009417-458rrhcm	145	8	intent	intent	NN
cord-009417-458rrhcm	145	9	of	of	IN
cord-009417-458rrhcm	145	10	establishing	establish	VBG
cord-009417-458rrhcm	145	11	parameters	parameter	NNS
cord-009417-458rrhcm	145	12	,	,	,
cord-009417-458rrhcm	145	13	not	not	RB
cord-009417-458rrhcm	145	14	with	with	IN
cord-009417-458rrhcm	145	15	the	the	DT
cord-009417-458rrhcm	145	16	intent	intent	NN
cord-009417-458rrhcm	145	17	of	of	IN
cord-009417-458rrhcm	145	18	substituting	substitute	VBG
cord-009417-458rrhcm	145	19	for	for	IN
cord-009417-458rrhcm	145	20	the	the	DT
cord-009417-458rrhcm	145	21	individual	individual	JJ
cord-009417-458rrhcm	145	22	clinician	clinician	NN
cord-009417-458rrhcm	145	23	's	's	POS
cord-009417-458rrhcm	145	24	judgment	judgment	NN
cord-009417-458rrhcm	145	25	.	.	.
cord-009417-458rrhcm	146	1	The	the	DT
cord-009417-458rrhcm	146	2	art	art	NN
cord-009417-458rrhcm	146	3	of	of	IN
cord-009417-458rrhcm	146	4	medical	medical	JJ
cord-009417-458rrhcm	146	5	decision	decision	NN
cord-009417-458rrhcm	146	6	making	make	VBG
cord-009417-458rrhcm	146	7	in	in	IN
cord-009417-458rrhcm	146	8	transfusion	transfusion	NN
cord-009417-458rrhcm	146	9	,	,	,
cord-009417-458rrhcm	146	10	as	as	IN
cord-009417-458rrhcm	146	11	in	in	IN
cord-009417-458rrhcm	146	12	other	other	JJ
cord-009417-458rrhcm	146	13	areas	area	NNS
cord-009417-458rrhcm	146	14	of	of	IN
cord-009417-458rrhcm	146	15	medicine	medicine	NN
cord-009417-458rrhcm	146	16	,	,	,
cord-009417-458rrhcm	146	17	lies	lie	VBZ
cord-009417-458rrhcm	146	18	in	in	IN
cord-009417-458rrhcm	146	19	determination	determination	NN
cord-009417-458rrhcm	146	20	of	of	IN
cord-009417-458rrhcm	146	21	the	the	DT
cord-009417-458rrhcm	146	22	appropriate	appropriate	JJ
cord-009417-458rrhcm	146	23	treatment	treatment	NN
cord-009417-458rrhcm	146	24	for	for	IN
cord-009417-458rrhcm	146	25	the	the	DT
cord-009417-458rrhcm	146	26	individual	individual	JJ
cord-009417-458rrhcm	146	27	patient	patient	NN
cord-009417-458rrhcm	146	28	.	.	.
cord-009417-458rrhcm	147	1	A	a	DT
cord-009417-458rrhcm	147	2	platelet	platelet	NN
cord-009417-458rrhcm	147	3	concentrate	concentrate	NN
cord-009417-458rrhcm	148	1	(	(	-LRB-
cord-009417-458rrhcm	148	2	random	random	JJ
cord-009417-458rrhcm	148	3	-	-	HYPH
cord-009417-458rrhcm	148	4	donor	donor	NN
cord-009417-458rrhcm	148	5	platelets	platelet	NNS
cord-009417-458rrhcm	148	6	)	)	-RRB-
cord-009417-458rrhcm	148	7	is	be	VBZ
cord-009417-458rrhcm	148	8	obtained	obtain	VBN
cord-009417-458rrhcm	148	9	by	by	IN
cord-009417-458rrhcm	148	10	centrifugation	centrifugation	NN
cord-009417-458rrhcm	148	11	from	from	IN
cord-009417-458rrhcm	148	12	a	a	DT
cord-009417-458rrhcm	148	13	unit	unit	NN
cord-009417-458rrhcm	148	14	of	of	IN
cord-009417-458rrhcm	148	15	donated	donate	VBN
cord-009417-458rrhcm	148	16	WB	WB	NNP
cord-009417-458rrhcm	148	17	.	.	.
cord-009417-458rrhcm	149	1	Each	each	DT
cord-009417-458rrhcm	149	2	unit	unit	NN
cord-009417-458rrhcm	149	3	contains	contain	VBZ
cord-009417-458rrhcm	149	4	a	a	DT
cord-009417-458rrhcm	149	5	minimum	minimum	NN
cord-009417-458rrhcm	149	6	of	of	IN
cord-009417-458rrhcm	149	7	55	55	CD
cord-009417-458rrhcm	149	8	×	×	CD
cord-009417-458rrhcm	149	9	10	10	CD
cord-009417-458rrhcm	149	10	10	10	CD
cord-009417-458rrhcm	149	11	platelets	platelet	NNS
cord-009417-458rrhcm	149	12	suspended	suspend	VBN
cord-009417-458rrhcm	149	13	in	in	IN
cord-009417-458rrhcm	149	14	about	about	RB
cord-009417-458rrhcm	149	15	50	50	CD
cord-009417-458rrhcm	149	16	mL	mL	NNS
cord-009417-458rrhcm	149	17	of	of	IN
cord-009417-458rrhcm	149	18	plasma	plasma	NN
cord-009417-458rrhcm	149	19	.	.	.
cord-009417-458rrhcm	150	1	Platelets	platelet	NNS
cord-009417-458rrhcm	150	2	are	be	VBP
cord-009417-458rrhcm	150	3	stored	store	VBN
cord-009417-458rrhcm	150	4	at	at	IN
cord-009417-458rrhcm	150	5	room	room	NN
cord-009417-458rrhcm	150	6	temperature	temperature	NN
cord-009417-458rrhcm	150	7	to	to	TO
cord-009417-458rrhcm	150	8	avoid	avoid	VB
cord-009417-458rrhcm	150	9	loss	loss	NN
cord-009417-458rrhcm	150	10	of	of	IN
cord-009417-458rrhcm	150	11	function	function	NN
cord-009417-458rrhcm	150	12	from	from	IN
cord-009417-458rrhcm	150	13	refrigeration	refrigeration	NN
cord-009417-458rrhcm	150	14	and	and	CC
cord-009417-458rrhcm	150	15	are	be	VBP
cord-009417-458rrhcm	150	16	constantly	constantly	RB
cord-009417-458rrhcm	150	17	agitated	agitated	JJ
cord-009417-458rrhcm	150	18	to	to	TO
cord-009417-458rrhcm	150	19	maximize	maximize	VB
cord-009417-458rrhcm	150	20	gas	gas	NN
cord-009417-458rrhcm	150	21	exchange	exchange	NN
cord-009417-458rrhcm	150	22	.	.	.
cord-009417-458rrhcm	151	1	The	the	DT
cord-009417-458rrhcm	151	2	length	length	NN
cord-009417-458rrhcm	151	3	of	of	IN
cord-009417-458rrhcm	151	4	storage	storage	NN
cord-009417-458rrhcm	151	5	varies	vary	VBZ
cord-009417-458rrhcm	151	6	with	with	IN
cord-009417-458rrhcm	151	7	the	the	DT
cord-009417-458rrhcm	151	8	container	container	NN
cord-009417-458rrhcm	151	9	used	use	VBN
cord-009417-458rrhcm	151	10	,	,	,
cord-009417-458rrhcm	151	11	but	but	CC
cord-009417-458rrhcm	151	12	most	most	JJS
cord-009417-458rrhcm	151	13	systems	system	NNS
cord-009417-458rrhcm	151	14	permit	permit	VBP
cord-009417-458rrhcm	151	15	5-day	5-day	JJ
cord-009417-458rrhcm	151	16	storage	storage	NN
cord-009417-458rrhcm	151	17	.	.	.
cord-009417-458rrhcm	152	1	Because	because	IN
cord-009417-458rrhcm	152	2	of	of	IN
cord-009417-458rrhcm	152	3	this	this	DT
cord-009417-458rrhcm	152	4	limited	limited	JJ
cord-009417-458rrhcm	152	5	storage	storage	NN
cord-009417-458rrhcm	152	6	time	time	NN
cord-009417-458rrhcm	152	7	and	and	CC
cord-009417-458rrhcm	152	8	the	the	DT
cord-009417-458rrhcm	152	9	increasing	increase	VBG
cord-009417-458rrhcm	152	10	demand	demand	NN
cord-009417-458rrhcm	152	11	for	for	IN
cord-009417-458rrhcm	152	12	this	this	DT
cord-009417-458rrhcm	152	13	component	component	NN
cord-009417-458rrhcm	152	14	,	,	,
cord-009417-458rrhcm	152	15	platelets	platelet	NNS
cord-009417-458rrhcm	152	16	are	be	VBP
cord-009417-458rrhcm	152	17	often	often	RB
cord-009417-458rrhcm	152	18	subject	subject	JJ
cord-009417-458rrhcm	152	19	to	to	IN
cord-009417-458rrhcm	152	20	supply	supply	NN
cord-009417-458rrhcm	152	21	shortages	shortage	NNS
cord-009417-458rrhcm	152	22	.	.	.
cord-009417-458rrhcm	153	1	Some	some	DT
cord-009417-458rrhcm	153	2	loss	loss	NN
cord-009417-458rrhcm	153	3	of	of	IN
cord-009417-458rrhcm	153	4	viability	viability	NN
cord-009417-458rrhcm	153	5	and	and	CC
cord-009417-458rrhcm	153	6	platelet	platelet	NN
cord-009417-458rrhcm	153	7	numbers	number	NNS
cord-009417-458rrhcm	153	8	occurs	occur	VBZ
cord-009417-458rrhcm	153	9	during	during	IN
cord-009417-458rrhcm	153	10	storage	storage	NN
cord-009417-458rrhcm	153	11	,	,	,
cord-009417-458rrhcm	153	12	but	but	CC
cord-009417-458rrhcm	153	13	5-day	5-day	JJ
cord-009417-458rrhcm	153	14	-	-	HYPH
cord-009417-458rrhcm	153	15	old	old	JJ
cord-009417-458rrhcm	153	16	platelets	platelet	NNS
cord-009417-458rrhcm	153	17	still	still	RB
cord-009417-458rrhcm	153	18	effect	effect	VBP
cord-009417-458rrhcm	153	19	hemostasis	hemostasis	NN
cord-009417-458rrhcm	153	20	.	.	.
cord-009417-458rrhcm	154	1	Once	once	IN
cord-009417-458rrhcm	154	2	the	the	DT
cord-009417-458rrhcm	154	3	bags	bag	NNS
cord-009417-458rrhcm	154	4	are	be	VBP
cord-009417-458rrhcm	154	5	entered	enter	VBN
cord-009417-458rrhcm	154	6	for	for	IN
cord-009417-458rrhcm	154	7	pooling	pool	VBG
cord-009417-458rrhcm	154	8	before	before	IN
cord-009417-458rrhcm	154	9	transfusion	transfusion	NN
cord-009417-458rrhcm	154	10	,	,	,
cord-009417-458rrhcm	154	11	the	the	DT
cord-009417-458rrhcm	154	12	platelets	platelet	NNS
cord-009417-458rrhcm	154	13	must	must	MD
cord-009417-458rrhcm	154	14	be	be	VB
cord-009417-458rrhcm	154	15	administered	administer	VBN
cord-009417-458rrhcm	154	16	within	within	IN
cord-009417-458rrhcm	154	17	4	4	CD
cord-009417-458rrhcm	154	18	hours	hour	NNS
cord-009417-458rrhcm	154	19	.	.	.
cord-009417-458rrhcm	155	1	Each	each	DT
cord-009417-458rrhcm	155	2	unit	unit	NN
cord-009417-458rrhcm	155	3	of	of	IN
cord-009417-458rrhcm	155	4	platelets	platelet	NNS
cord-009417-458rrhcm	155	5	is	be	VBZ
cord-009417-458rrhcm	155	6	expected	expect	VBN
cord-009417-458rrhcm	155	7	to	to	TO
cord-009417-458rrhcm	155	8	increase	increase	VB
cord-009417-458rrhcm	155	9	the	the	DT
cord-009417-458rrhcm	155	10	platelet	platelet	NN
cord-009417-458rrhcm	155	11	count	count	NN
cord-009417-458rrhcm	155	12	by	by	IN
cord-009417-458rrhcm	155	13	10	10	CD
cord-009417-458rrhcm	155	14	×	×	NN
cord-009417-458rrhcm	155	15	10	10	CD
cord-009417-458rrhcm	155	16	9	9	CD
cord-009417-458rrhcm	155	17	/L	/L	.
cord-009417-458rrhcm	155	18	in	in	IN
cord-009417-458rrhcm	155	19	a	a	DT
cord-009417-458rrhcm	155	20	typical	typical	JJ
cord-009417-458rrhcm	155	21	70-kg	70-kg	CD
cord-009417-458rrhcm	155	22	adult	adult	NN
cord-009417-458rrhcm	155	23	.	.	.
cord-009417-458rrhcm	156	1	The	the	DT
cord-009417-458rrhcm	156	2	usual	usual	JJ
cord-009417-458rrhcm	156	3	dose	dose	NN
cord-009417-458rrhcm	156	4	is	be	VBZ
cord-009417-458rrhcm	156	5	6	6	CD
cord-009417-458rrhcm	156	6	units	unit	NNS
cord-009417-458rrhcm	156	7	,	,	,
cord-009417-458rrhcm	156	8	or	or	CC
cord-009417-458rrhcm	156	9	1	1	CD
cord-009417-458rrhcm	156	10	U/10	u/10	CD
cord-009417-458rrhcm	156	11	kg	kg	NNS
cord-009417-458rrhcm	156	12	of	of	IN
cord-009417-458rrhcm	156	13	body	body	NN
cord-009417-458rrhcm	156	14	weight	weight	NN
cord-009417-458rrhcm	156	15	.	.	.
cord-009417-458rrhcm	157	1	A	a	DT
cord-009417-458rrhcm	157	2	1-hour	1-hour	CD
cord-009417-458rrhcm	157	3	post	post	JJ
cord-009417-458rrhcm	157	4	-	-	JJ
cord-009417-458rrhcm	157	5	transfusion	transfusion	JJ
cord-009417-458rrhcm	157	6	platelet	platelet	NN
cord-009417-458rrhcm	157	7	count	count	NN
cord-009417-458rrhcm	157	8	should	should	MD
cord-009417-458rrhcm	157	9	be	be	VB
cord-009417-458rrhcm	157	10	obtained	obtain	VBN
cord-009417-458rrhcm	157	11	to	to	TO
cord-009417-458rrhcm	157	12	determine	determine	VB
cord-009417-458rrhcm	157	13	the	the	DT
cord-009417-458rrhcm	157	14	adequacy	adequacy	NN
cord-009417-458rrhcm	157	15	of	of	IN
cord-009417-458rrhcm	157	16	response	response	NN
cord-009417-458rrhcm	157	17	.	.	.
cord-009417-458rrhcm	158	1	The	the	DT
cord-009417-458rrhcm	158	2	following	following	JJ
cord-009417-458rrhcm	158	3	equation	equation	NN
cord-009417-458rrhcm	158	4	,	,	,
cord-009417-458rrhcm	158	5	which	which	WDT
cord-009417-458rrhcm	158	6	relates	relate	VBZ
cord-009417-458rrhcm	158	7	platelet	platelet	NN
cord-009417-458rrhcm	158	8	number	number	NN
cord-009417-458rrhcm	158	9	and	and	CC
cord-009417-458rrhcm	158	10	body	body	NN
cord-009417-458rrhcm	158	11	size	size	NN
cord-009417-458rrhcm	158	12	to	to	IN
cord-009417-458rrhcm	158	13	the	the	DT
cord-009417-458rrhcm	158	14	post	post	JJ
cord-009417-458rrhcm	158	15	-	-	JJ
cord-009417-458rrhcm	158	16	transfusion	transfusion	JJ
cord-009417-458rrhcm	158	17	increment	increment	NN
cord-009417-458rrhcm	158	18	,	,	,
cord-009417-458rrhcm	158	19	can	can	MD
cord-009417-458rrhcm	158	20	be	be	VB
cord-009417-458rrhcm	158	21	used	use	VBN
cord-009417-458rrhcm	158	22	to	to	TO
cord-009417-458rrhcm	158	23	assess	assess	VB
cord-009417-458rrhcm	158	24	the	the	DT
cord-009417-458rrhcm	158	25	effectiveness	effectiveness	NN
cord-009417-458rrhcm	158	26	of	of	IN
cord-009417-458rrhcm	158	27	the	the	DT
cord-009417-458rrhcm	158	28	transfusion	transfusion	NN
cord-009417-458rrhcm	158	29	:	:	:
cord-009417-458rrhcm	158	30	ABO	ABO	NNP
cord-009417-458rrhcm	158	31	-	-	HYPH
cord-009417-458rrhcm	158	32	compatible	compatible	JJ
cord-009417-458rrhcm	158	33	platelets	platelet	NNS
cord-009417-458rrhcm	158	34	are	be	VBP
cord-009417-458rrhcm	158	35	desirable	desirable	JJ
cord-009417-458rrhcm	158	36	but	but	CC
cord-009417-458rrhcm	158	37	not	not	RB
cord-009417-458rrhcm	158	38	essential	essential	JJ
cord-009417-458rrhcm	158	39	.	.	.
cord-009417-458rrhcm	159	1	When	when	WRB
cord-009417-458rrhcm	159	2	ABO	ABO	NNP
cord-009417-458rrhcm	159	3	-	-	HYPH
cord-009417-458rrhcm	159	4	mismatched	mismatch	VBN
cord-009417-458rrhcm	159	5	platelets	platelet	NNS
cord-009417-458rrhcm	159	6	are	be	VBP
cord-009417-458rrhcm	159	7	given	give	VBN
cord-009417-458rrhcm	159	8	,	,	,
cord-009417-458rrhcm	159	9	removal	removal	NN
cord-009417-458rrhcm	159	10	of	of	IN
cord-009417-458rrhcm	159	11	some	some	DT
cord-009417-458rrhcm	159	12	of	of	IN
cord-009417-458rrhcm	159	13	the	the	DT
cord-009417-458rrhcm	159	14	incompatible	incompatible	JJ
cord-009417-458rrhcm	159	15	plasma	plasma	NN
cord-009417-458rrhcm	159	16	can	can	MD
cord-009417-458rrhcm	159	17	be	be	VB
cord-009417-458rrhcm	159	18	carried	carry	VBN
cord-009417-458rrhcm	159	19	out	out	RP
cord-009417-458rrhcm	159	20	at	at	IN
cord-009417-458rrhcm	159	21	the	the	DT
cord-009417-458rrhcm	159	22	time	time	NN
cord-009417-458rrhcm	159	23	of	of	IN
cord-009417-458rrhcm	159	24	pooling	pool	VBG
cord-009417-458rrhcm	159	25	for	for	IN
cord-009417-458rrhcm	159	26	transfusion	transfusion	NN
cord-009417-458rrhcm	159	27	.	.	.
cord-009417-458rrhcm	160	1	Likewise	likewise	RB
cord-009417-458rrhcm	160	2	,	,	,
cord-009417-458rrhcm	160	3	volume	volume	NN
cord-009417-458rrhcm	160	4	reduction	reduction	NN
cord-009417-458rrhcm	160	5	may	may	MD
cord-009417-458rrhcm	160	6	be	be	VB
cord-009417-458rrhcm	160	7	necessary	necessary	JJ
cord-009417-458rrhcm	160	8	for	for	IN
cord-009417-458rrhcm	160	9	patients	patient	NNS
cord-009417-458rrhcm	160	10	at	at	IN
cord-009417-458rrhcm	160	11	risk	risk	NN
cord-009417-458rrhcm	160	12	for	for	IN
cord-009417-458rrhcm	160	13	fl	fl	NNP
cord-009417-458rrhcm	160	14	uid	uid	NN
cord-009417-458rrhcm	160	15	overload	overload	NN
cord-009417-458rrhcm	160	16	from	from	IN
cord-009417-458rrhcm	160	17	the	the	DT
cord-009417-458rrhcm	160	18	300	300	CD
cord-009417-458rrhcm	160	19	to	to	TO
cord-009417-458rrhcm	160	20	500	500	CD
cord-009417-458rrhcm	160	21	mL	ml	NN
cord-009417-458rrhcm	160	22	of	of	IN
cord-009417-458rrhcm	160	23	plasma	plasma	NN
cord-009417-458rrhcm	160	24	present	present	JJ
cord-009417-458rrhcm	160	25	in	in	IN
cord-009417-458rrhcm	160	26	6	6	CD
cord-009417-458rrhcm	160	27	to	to	TO
cord-009417-458rrhcm	160	28	10	10	CD
cord-009417-458rrhcm	160	29	units	unit	NNS
cord-009417-458rrhcm	160	30	of	of	IN
cord-009417-458rrhcm	160	31	platelets	platelet	NNS
cord-009417-458rrhcm	160	32	.	.	.
cord-009417-458rrhcm	161	1	Nonetheless	nonetheless	RB
cord-009417-458rrhcm	161	2	,	,	,
cord-009417-458rrhcm	161	3	the	the	DT
cord-009417-458rrhcm	161	4	remaining	remain	VBG
cord-009417-458rrhcm	161	5	plasma	plasma	NN
cord-009417-458rrhcm	161	6	is	be	VBZ
cord-009417-458rrhcm	161	7	a	a	DT
cord-009417-458rrhcm	161	8	good	good	JJ
cord-009417-458rrhcm	161	9	source	source	NN
cord-009417-458rrhcm	161	10	of	of	IN
cord-009417-458rrhcm	161	11	stable	stable	JJ
cord-009417-458rrhcm	161	12	coagulation	coagulation	NN
cord-009417-458rrhcm	161	13	factors	factor	NNS
cord-009417-458rrhcm	161	14	and	and	CC
cord-009417-458rrhcm	161	15	contains	contain	VBZ
cord-009417-458rrhcm	161	16	diminished	diminish	VBN
cord-009417-458rrhcm	161	17	but	but	CC
cord-009417-458rrhcm	161	18	still	still	RB
cord-009417-458rrhcm	161	19	potentially	potentially	RB
cord-009417-458rrhcm	161	20	benefi	benefi	JJ
cord-009417-458rrhcm	161	21	cial	cial	JJ
cord-009417-458rrhcm	161	22	amounts	amount	NNS
cord-009417-458rrhcm	161	23	of	of	IN
cord-009417-458rrhcm	161	24	factors	factor	NNS
cord-009417-458rrhcm	161	25	V	v	NN
cord-009417-458rrhcm	161	26	and	and	CC
cord-009417-458rrhcm	161	27	VIII	VIII	NNP
cord-009417-458rrhcm	161	28	.	.	.
cord-009417-458rrhcm	162	1	There	there	EX
cord-009417-458rrhcm	162	2	is	be	VBZ
cord-009417-458rrhcm	162	3	no	no	DT
cord-009417-458rrhcm	162	4	contraindication	contraindication	NN
cord-009417-458rrhcm	162	5	to	to	IN
cord-009417-458rrhcm	162	6	the	the	DT
cord-009417-458rrhcm	162	7	use	use	NN
cord-009417-458rrhcm	162	8	of	of	IN
cord-009417-458rrhcm	162	9	Rh	Rh	NNP
cord-009417-458rrhcm	162	10	-	-	HYPH
cord-009417-458rrhcm	162	11	positive	positive	JJ
cord-009417-458rrhcm	162	12	platelets	platelet	NNS
cord-009417-458rrhcm	162	13	in	in	IN
cord-009417-458rrhcm	162	14	Rh	Rh	NNP
cord-009417-458rrhcm	162	15	-	-	HYPH
cord-009417-458rrhcm	162	16	negative	negative	JJ
cord-009417-458rrhcm	162	17	patients	patient	NNS
cord-009417-458rrhcm	162	18	;	;	:
cord-009417-458rrhcm	162	19	if	if	IN
cord-009417-458rrhcm	162	20	given	give	VBN
cord-009417-458rrhcm	162	21	to	to	IN
cord-009417-458rrhcm	162	22	women	woman	NNS
cord-009417-458rrhcm	162	23	with	with	IN
cord-009417-458rrhcm	162	24	future	future	JJ
cord-009417-458rrhcm	162	25	childbearing	childbearing	NN
cord-009417-458rrhcm	162	26	potential	potential	NN
cord-009417-458rrhcm	162	27	,	,	,
cord-009417-458rrhcm	162	28	Rh	Rh	NNP
cord-009417-458rrhcm	162	29	immune	immune	JJ
cord-009417-458rrhcm	162	30	globulin	globulin	NN
cord-009417-458rrhcm	162	31	(	(	-LRB-
cord-009417-458rrhcm	162	32	RhIG	RhIG	NNP
cord-009417-458rrhcm	162	33	)	)	-RRB-
cord-009417-458rrhcm	162	34	may	may	MD
cord-009417-458rrhcm	162	35	be	be	VB
cord-009417-458rrhcm	162	36	used	use	VBN
cord-009417-458rrhcm	162	37	prophylactically	prophylactically	RB
cord-009417-458rrhcm	162	38	against	against	IN
cord-009417-458rrhcm	162	39	the	the	DT
cord-009417-458rrhcm	162	40	small	small	JJ
cord-009417-458rrhcm	162	41	risk	risk	NN
cord-009417-458rrhcm	162	42	of	of	IN
cord-009417-458rrhcm	162	43	Rh	Rh	NNP
cord-009417-458rrhcm	162	44	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	162	45	from	from	IN
cord-009417-458rrhcm	162	46	red	red	JJ
cord-009417-458rrhcm	162	47	cells	cell	NNS
cord-009417-458rrhcm	162	48	that	that	WDT
cord-009417-458rrhcm	162	49	may	may	MD
cord-009417-458rrhcm	162	50	be	be	VB
cord-009417-458rrhcm	162	51	contained	contain	VBN
cord-009417-458rrhcm	162	52	in	in	IN
cord-009417-458rrhcm	162	53	the	the	DT
cord-009417-458rrhcm	162	54	platelet	platelet	NN
cord-009417-458rrhcm	162	55	concentrate	concentrate	NN
cord-009417-458rrhcm	162	56	.	.	.
cord-009417-458rrhcm	163	1	Plateletpheresis	Plateletpheresis	NNP
cord-009417-458rrhcm	163	2	(	(	-LRB-
cord-009417-458rrhcm	163	3	common	common	JJ
cord-009417-458rrhcm	163	4	terms	term	NNS
cord-009417-458rrhcm	163	5	:	:	:
cord-009417-458rrhcm	163	6	single	single	JJ
cord-009417-458rrhcm	163	7	-	-	HYPH
cord-009417-458rrhcm	163	8	donor	donor	NN
cord-009417-458rrhcm	163	9	platelets	platelet	NNS
cord-009417-458rrhcm	163	10	,	,	,
cord-009417-458rrhcm	163	11	apheresis	apheresis	NN
cord-009417-458rrhcm	163	12	platelets	platelet	NNS
cord-009417-458rrhcm	163	13	)	)	-RRB-
cord-009417-458rrhcm	163	14	involves	involve	VBZ
cord-009417-458rrhcm	163	15	separating	separate	VBG
cord-009417-458rrhcm	163	16	and	and	CC
cord-009417-458rrhcm	163	17	removing	remove	VBG
cord-009417-458rrhcm	163	18	platelets	platelet	NNS
cord-009417-458rrhcm	163	19	from	from	IN
cord-009417-458rrhcm	163	20	one	one	CD
cord-009417-458rrhcm	163	21	donor	donor	NN
cord-009417-458rrhcm	163	22	by	by	IN
cord-009417-458rrhcm	163	23	cytapheresis	cytapheresis	NNP
cord-009417-458rrhcm	163	24	during	during	IN
cord-009417-458rrhcm	163	25	a	a	DT
cord-009417-458rrhcm	163	26	1	1	CD
cord-009417-458rrhcm	163	27	1	1	CD
cord-009417-458rrhcm	163	28	/	/	SYM
cord-009417-458rrhcm	163	29	2	2	CD
cord-009417-458rrhcm	163	30	-to	-to	SYM
cord-009417-458rrhcm	163	31	2-hour	2-hour	JJ
cord-009417-458rrhcm	163	32	procedure	procedure	NN
cord-009417-458rrhcm	163	33	on	on	IN
cord-009417-458rrhcm	163	34	an	an	DT
cord-009417-458rrhcm	163	35	automated	automate	VBN
cord-009417-458rrhcm	163	36	device	device	NN
cord-009417-458rrhcm	163	37	and	and	CC
cord-009417-458rrhcm	163	38	then	then	RB
cord-009417-458rrhcm	163	39	retransfusing	retransfuse	VBG
cord-009417-458rrhcm	163	40	the	the	DT
cord-009417-458rrhcm	163	41	remainder	remainder	NN
cord-009417-458rrhcm	163	42	of	of	IN
cord-009417-458rrhcm	163	43	the	the	DT
cord-009417-458rrhcm	163	44	blood	blood	NN
cord-009417-458rrhcm	163	45	back	back	RB
cord-009417-458rrhcm	163	46	into	into	IN
cord-009417-458rrhcm	163	47	the	the	DT
cord-009417-458rrhcm	163	48	donor	donor	NN
cord-009417-458rrhcm	163	49	.	.	.
cord-009417-458rrhcm	164	1	Each	each	DT
cord-009417-458rrhcm	164	2	collection	collection	NN
cord-009417-458rrhcm	164	3	contains	contain	VBZ
cord-009417-458rrhcm	164	4	an	an	DT
cord-009417-458rrhcm	164	5	equivalent	equivalent	NN
cord-009417-458rrhcm	164	6	of	of	IN
cord-009417-458rrhcm	164	7	6	6	CD
cord-009417-458rrhcm	164	8	to	to	TO
cord-009417-458rrhcm	164	9	10	10	CD
cord-009417-458rrhcm	164	10	units	unit	NNS
cord-009417-458rrhcm	164	11	of	of	IN
cord-009417-458rrhcm	164	12	platelet	platelet	NN
cord-009417-458rrhcm	164	13	concentrates	concentrate	NNS
cord-009417-458rrhcm	164	14	.	.	.
cord-009417-458rrhcm	165	1	Single	single	JJ
cord-009417-458rrhcm	165	2	-	-	HYPH
cord-009417-458rrhcm	165	3	donor	donor	NN
cord-009417-458rrhcm	165	4	platelets	platelet	NNS
cord-009417-458rrhcm	165	5	are	be	VBP
cord-009417-458rrhcm	165	6	suspended	suspend	VBN
cord-009417-458rrhcm	165	7	in	in	IN
cord-009417-458rrhcm	165	8	about	about	RB
cord-009417-458rrhcm	165	9	300	300	CD
cord-009417-458rrhcm	165	10	mL	ml	NN
cord-009417-458rrhcm	165	11	of	of	IN
cord-009417-458rrhcm	165	12	plasma	plasma	NN
cord-009417-458rrhcm	165	13	,	,	,
cord-009417-458rrhcm	165	14	so	so	RB
cord-009417-458rrhcm	165	15	the	the	DT
cord-009417-458rrhcm	165	16	same	same	JJ
cord-009417-458rrhcm	165	17	ABO	ABO	NNP
cord-009417-458rrhcm	165	18	and	and	CC
cord-009417-458rrhcm	165	19	volume	volume	NN
cord-009417-458rrhcm	165	20	considerations	consideration	NNS
cord-009417-458rrhcm	165	21	discussed	discuss	VBD
cord-009417-458rrhcm	165	22	earlier	early	RBR
cord-009417-458rrhcm	165	23	pertain	pertain	VBP
cord-009417-458rrhcm	165	24	.	.	.
cord-009417-458rrhcm	166	1	Single	single	JJ
cord-009417-458rrhcm	166	2	-	-	HYPH
cord-009417-458rrhcm	166	3	donor	donor	NN
cord-009417-458rrhcm	166	4	platelets	platelet	NNS
cord-009417-458rrhcm	166	5	offer	offer	VBP
cord-009417-458rrhcm	166	6	the	the	DT
cord-009417-458rrhcm	166	7	clear	clear	JJ
cord-009417-458rrhcm	166	8	benefi	benefi	NNP
cord-009417-458rrhcm	166	9	t	t	NN
cord-009417-458rrhcm	166	10	of	of	IN
cord-009417-458rrhcm	166	11	reducing	reduce	VBG
cord-009417-458rrhcm	166	12	the	the	DT
cord-009417-458rrhcm	166	13	risk	risk	NN
cord-009417-458rrhcm	166	14	of	of	IN
cord-009417-458rrhcm	166	15	multiple	multiple	JJ
cord-009417-458rrhcm	166	16	-	-	HYPH
cord-009417-458rrhcm	166	17	donor	donor	NN
cord-009417-458rrhcm	166	18	exposure	exposure	NN
cord-009417-458rrhcm	166	19	to	to	IN
cord-009417-458rrhcm	166	20	the	the	DT
cord-009417-458rrhcm	166	21	recipient	recipient	NN
cord-009417-458rrhcm	166	22	.	.	.
cord-009417-458rrhcm	167	1	Single	single	JJ
cord-009417-458rrhcm	167	2	-	-	HYPH
cord-009417-458rrhcm	167	3	donor	donor	NN
cord-009417-458rrhcm	167	4	platelets	platelet	NNS
cord-009417-458rrhcm	167	5	may	may	MD
cord-009417-458rrhcm	167	6	also	also	RB
cord-009417-458rrhcm	167	7	be	be	VB
cord-009417-458rrhcm	167	8	the	the	DT
cord-009417-458rrhcm	167	9	only	only	JJ
cord-009417-458rrhcm	167	10	available	available	JJ
cord-009417-458rrhcm	167	11	alternative	alternative	NN
cord-009417-458rrhcm	167	12	for	for	IN
cord-009417-458rrhcm	167	13	recipients	recipient	NNS
cord-009417-458rrhcm	167	14	who	who	WP
cord-009417-458rrhcm	167	15	have	have	VBP
cord-009417-458rrhcm	167	16	been	be	VBN
cord-009417-458rrhcm	167	17	alloimmunized	alloimmunize	VBN
cord-009417-458rrhcm	167	18	by	by	IN
cord-009417-458rrhcm	167	19	previous	previous	JJ
cord-009417-458rrhcm	167	20	platelet	platelet	NN
cord-009417-458rrhcm	167	21	transfusions	transfusion	NNS
cord-009417-458rrhcm	167	22	because	because	IN
cord-009417-458rrhcm	167	23	they	-PRON-	PRP
cord-009417-458rrhcm	167	24	may	may	MD
cord-009417-458rrhcm	167	25	be	be	VB
cord-009417-458rrhcm	167	26	human	human	JJ
cord-009417-458rrhcm	167	27	leukocyte	leukocyte	NN
cord-009417-458rrhcm	167	28	antigen	antigen	NN
cord-009417-458rrhcm	167	29	(	(	-LRB-
cord-009417-458rrhcm	167	30	HLA	HLA	NNP
cord-009417-458rrhcm	167	31	)	)	-RRB-
cord-009417-458rrhcm	167	32	or	or	CC
cord-009417-458rrhcm	167	33	platelet	platelet	NN
cord-009417-458rrhcm	167	34	antigen	antigen	NN
cord-009417-458rrhcm	167	35	matched	match	VBN
cord-009417-458rrhcm	167	36	to	to	IN
cord-009417-458rrhcm	167	37	the	the	DT
cord-009417-458rrhcm	167	38	recipient	recipient	NN
cord-009417-458rrhcm	167	39	.	.	.
cord-009417-458rrhcm	168	1	The	the	DT
cord-009417-458rrhcm	168	2	use	use	NN
cord-009417-458rrhcm	168	3	of	of	IN
cord-009417-458rrhcm	168	4	apheresis	apheresis	NN
cord-009417-458rrhcm	168	5	platelets	platelet	NNS
cord-009417-458rrhcm	168	6	now	now	RB
cord-009417-458rrhcm	168	7	exceeds	exceed	VBZ
cord-009417-458rrhcm	168	8	the	the	DT
cord-009417-458rrhcm	168	9	use	use	NN
cord-009417-458rrhcm	168	10	of	of	IN
cord-009417-458rrhcm	168	11	pooled	pool	VBN
cord-009417-458rrhcm	168	12	random	random	JJ
cord-009417-458rrhcm	168	13	-	-	HYPH
cord-009417-458rrhcm	168	14	donor	donor	NN
cord-009417-458rrhcm	168	15	platelets	platelet	NNS
cord-009417-458rrhcm	168	16	;	;	:
cord-009417-458rrhcm	168	17	however	however	RB
cord-009417-458rrhcm	168	18	,	,	,
cord-009417-458rrhcm	168	19	use	use	NN
cord-009417-458rrhcm	168	20	of	of	IN
cord-009417-458rrhcm	168	21	this	this	DT
cord-009417-458rrhcm	168	22	product	product	NN
cord-009417-458rrhcm	168	23	in	in	IN
cord-009417-458rrhcm	168	24	emergency	emergency	NN
cord-009417-458rrhcm	168	25	situations	situation	NNS
cord-009417-458rrhcm	168	26	is	be	VBZ
cord-009417-458rrhcm	168	27	limited	limit	VBN
cord-009417-458rrhcm	168	28	by	by	IN
cord-009417-458rrhcm	168	29	the	the	DT
cord-009417-458rrhcm	168	30	availability	availability	NN
cord-009417-458rrhcm	168	31	of	of	IN
cord-009417-458rrhcm	168	32	volunteer	volunteer	NN
cord-009417-458rrhcm	168	33	donors	donor	NNS
cord-009417-458rrhcm	168	34	.	.	.
cord-009417-458rrhcm	169	1	35	35	CD
cord-009417-458rrhcm	169	2	Platelet	platelet	NN
cord-009417-458rrhcm	169	3	transfusions	transfusion	NNS
cord-009417-458rrhcm	169	4	are	be	VBP
cord-009417-458rrhcm	169	5	indicated	indicate	VBN
cord-009417-458rrhcm	169	6	for	for	IN
cord-009417-458rrhcm	169	7	patients	patient	NNS
cord-009417-458rrhcm	169	8	bleeding	bleed	VBG
cord-009417-458rrhcm	169	9	because	because	IN
cord-009417-458rrhcm	169	10	of	of	IN
cord-009417-458rrhcm	169	11	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	169	12	or	or	CC
cord-009417-458rrhcm	169	13	functional	functional	JJ
cord-009417-458rrhcm	169	14	platelet	platelet	NN
cord-009417-458rrhcm	169	15	defects	defect	NNS
cord-009417-458rrhcm	169	16	.	.	.
cord-009417-458rrhcm	170	1	36	36	CD
cord-009417-458rrhcm	170	2	Guidelines	guideline	NNS
cord-009417-458rrhcm	170	3	for	for	IN
cord-009417-458rrhcm	170	4	transfusion	transfusion	NN
cord-009417-458rrhcm	170	5	continue	continue	VBP
cord-009417-458rrhcm	170	6	to	to	TO
cord-009417-458rrhcm	170	7	evolve	evolve	VB
cord-009417-458rrhcm	170	8	,	,	,
cord-009417-458rrhcm	170	9	and	and	CC
cord-009417-458rrhcm	170	10	the	the	DT
cord-009417-458rrhcm	170	11	current	current	JJ
cord-009417-458rrhcm	170	12	guidelines	guideline	NNS
cord-009417-458rrhcm	170	13	merely	merely	RB
cord-009417-458rrhcm	170	14	provide	provide	VBP
cord-009417-458rrhcm	170	15	a	a	DT
cord-009417-458rrhcm	170	16	desirable	desirable	JJ
cord-009417-458rrhcm	170	17	range	range	NN
cord-009417-458rrhcm	170	18	for	for	IN
cord-009417-458rrhcm	170	19	platelet	platelet	NN
cord-009417-458rrhcm	170	20	counts	count	NNS
cord-009417-458rrhcm	170	21	,	,	,
cord-009417-458rrhcm	170	22	assuming	assume	VBG
cord-009417-458rrhcm	170	23	normal	normal	JJ
cord-009417-458rrhcm	170	24	platelet	platelet	NN
cord-009417-458rrhcm	170	25	func	func	NN
cord-009417-458rrhcm	170	26	-	-	HYPH
cord-009417-458rrhcm	170	27	tion	tion	NN
cord-009417-458rrhcm	170	28	(	(	-LRB-
cord-009417-458rrhcm	170	29	Table	table	NN
cord-009417-458rrhcm	170	30	80	80	CD
cord-009417-458rrhcm	170	31	-2	-2	CD
cord-009417-458rrhcm	170	32	)	)	-RRB-
cord-009417-458rrhcm	170	33	.	.	.
cord-009417-458rrhcm	171	1	There	there	EX
cord-009417-458rrhcm	171	2	is	be	VBZ
cord-009417-458rrhcm	171	3	ample	ample	JJ
cord-009417-458rrhcm	171	4	evidence	evidence	NN
cord-009417-458rrhcm	171	5	that	that	IN
cord-009417-458rrhcm	171	6	bleeding	bleed	VBG
cord-009417-458rrhcm	171	7	medical	medical	JJ
cord-009417-458rrhcm	171	8	or	or	CC
cord-009417-458rrhcm	171	9	surgical	surgical	JJ
cord-009417-458rrhcm	171	10	patients	patient	NNS
cord-009417-458rrhcm	171	11	with	with	IN
cord-009417-458rrhcm	171	12	platelet	platelet	NN
cord-009417-458rrhcm	171	13	counts	count	NNS
cord-009417-458rrhcm	171	14	of	of	IN
cord-009417-458rrhcm	171	15	50	50	CD
cord-009417-458rrhcm	171	16	×	×	NN
cord-009417-458rrhcm	171	17	10	10	CD
cord-009417-458rrhcm	171	18	9	9	CD
cord-009417-458rrhcm	171	19	/L	/L	,
cord-009417-458rrhcm	171	20	or	or	CC
cord-009417-458rrhcm	171	21	above	above	RB
cord-009417-458rrhcm	171	22	will	will	MD
cord-009417-458rrhcm	171	23	not	not	RB
cord-009417-458rrhcm	171	24	benefi	benefi	VB
cord-009417-458rrhcm	171	25	t	t	NN
cord-009417-458rrhcm	171	26	from	from	IN
cord-009417-458rrhcm	171	27	transfusion	transfusion	NN
cord-009417-458rrhcm	171	28	if	if	IN
cord-009417-458rrhcm	171	29	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	171	30	is	be	VBZ
cord-009417-458rrhcm	171	31	the	the	DT
cord-009417-458rrhcm	171	32	only	only	JJ
cord-009417-458rrhcm	171	33	abnormality	abnormality	NN
cord-009417-458rrhcm	171	34	.	.	.
cord-009417-458rrhcm	172	1	For	for	IN
cord-009417-458rrhcm	172	2	critical	critical	JJ
cord-009417-458rrhcm	172	3	invasive	invasive	JJ
cord-009417-458rrhcm	172	4	procedures	procedure	NNS
cord-009417-458rrhcm	172	5	in	in	IN
cord-009417-458rrhcm	172	6	which	which	WDT
cord-009417-458rrhcm	172	7	even	even	RB
cord-009417-458rrhcm	172	8	a	a	DT
cord-009417-458rrhcm	172	9	small	small	JJ
cord-009417-458rrhcm	172	10	amount	amount	NN
cord-009417-458rrhcm	172	11	of	of	IN
cord-009417-458rrhcm	172	12	bleeding	bleed	VBG
cord-009417-458rrhcm	172	13	could	could	MD
cord-009417-458rrhcm	172	14	lead	lead	VB
cord-009417-458rrhcm	172	15	to	to	IN
cord-009417-458rrhcm	172	16	loss	loss	NN
cord-009417-458rrhcm	172	17	of	of	IN
cord-009417-458rrhcm	172	18	vital	vital	JJ
cord-009417-458rrhcm	172	19	organ	organ	NN
cord-009417-458rrhcm	172	20	function	function	NN
cord-009417-458rrhcm	172	21	or	or	CC
cord-009417-458rrhcm	172	22	death	death	NN
cord-009417-458rrhcm	172	23	,	,	,
cord-009417-458rrhcm	172	24	maintaining	maintain	VBG
cord-009417-458rrhcm	172	25	the	the	DT
cord-009417-458rrhcm	172	26	platelet	platelet	NN
cord-009417-458rrhcm	172	27	count	count	NN
cord-009417-458rrhcm	172	28	at	at	IN
cord-009417-458rrhcm	172	29	50	50	CD
cord-009417-458rrhcm	172	30	×	×	NN
cord-009417-458rrhcm	172	31	10	10	CD
cord-009417-458rrhcm	172	32	9	9	CD
cord-009417-458rrhcm	172	33	/L	/L	,
cord-009417-458rrhcm	172	34	or	or	CC
cord-009417-458rrhcm	172	35	greater	great	JJR
cord-009417-458rrhcm	172	36	is	be	VBZ
cord-009417-458rrhcm	172	37	typically	typically	RB
cord-009417-458rrhcm	172	38	preferred	prefer	VBN
cord-009417-458rrhcm	172	39	.	.	.
cord-009417-458rrhcm	173	1	The	the	DT
cord-009417-458rrhcm	173	2	presence	presence	NN
cord-009417-458rrhcm	173	3	of	of	IN
cord-009417-458rrhcm	173	4	other	other	JJ
cord-009417-458rrhcm	173	5	factors	factor	NNS
cord-009417-458rrhcm	173	6	that	that	WDT
cord-009417-458rrhcm	173	7	diminish	diminish	VBP
cord-009417-458rrhcm	173	8	platelet	platelet	NN
cord-009417-458rrhcm	173	9	function	function	NN
cord-009417-458rrhcm	173	10	,	,	,
cord-009417-458rrhcm	173	11	such	such	JJ
cord-009417-458rrhcm	173	12	as	as	IN
cord-009417-458rrhcm	173	13	certain	certain	JJ
cord-009417-458rrhcm	173	14	drugs	drug	NNS
cord-009417-458rrhcm	173	15	,	,	,
cord-009417-458rrhcm	173	16	foreign	foreign	JJ
cord-009417-458rrhcm	173	17	intravascular	intravascular	JJ
cord-009417-458rrhcm	173	18	devices	device	NNS
cord-009417-458rrhcm	173	19	(	(	-LRB-
cord-009417-458rrhcm	173	20	e.g.	e.g.	RB
cord-009417-458rrhcm	173	21	,	,	,
cord-009417-458rrhcm	173	22	intra	intra	JJ
cord-009417-458rrhcm	173	23	-	-	JJ
cord-009417-458rrhcm	173	24	aortic	aortic	JJ
cord-009417-458rrhcm	173	25	balloon	balloon	NN
cord-009417-458rrhcm	173	26	pump	pump	NN
cord-009417-458rrhcm	173	27	or	or	CC
cord-009417-458rrhcm	173	28	membrane	membrane	NN
cord-009417-458rrhcm	173	29	oxygenator	oxygenator	NN
cord-009417-458rrhcm	173	30	)	)	-RRB-
cord-009417-458rrhcm	173	31	,	,	,
cord-009417-458rrhcm	173	32	infection	infection	NN
cord-009417-458rrhcm	173	33	,	,	,
cord-009417-458rrhcm	173	34	or	or	CC
cord-009417-458rrhcm	173	35	uremia	uremia	NN
cord-009417-458rrhcm	173	36	,	,	,
cord-009417-458rrhcm	173	37	may	may	MD
cord-009417-458rrhcm	173	38	alter	alter	VB
cord-009417-458rrhcm	173	39	this	this	DT
cord-009417-458rrhcm	173	40	requirement	requirement	NN
cord-009417-458rrhcm	173	41	upward	upward	RB
cord-009417-458rrhcm	173	42	.	.	.
cord-009417-458rrhcm	174	1	Patients	patient	NNS
cord-009417-458rrhcm	174	2	at	at	IN
cord-009417-458rrhcm	174	3	risk	risk	NN
cord-009417-458rrhcm	174	4	for	for	IN
cord-009417-458rrhcm	174	5	small	small	JJ
cord-009417-458rrhcm	174	6	but	but	CC
cord-009417-458rrhcm	174	7	strategically	strategically	RB
cord-009417-458rrhcm	174	8	important	important	JJ
cord-009417-458rrhcm	174	9	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	174	10	,	,	,
cord-009417-458rrhcm	174	11	such	such	JJ
cord-009417-458rrhcm	174	12	as	as	IN
cord-009417-458rrhcm	174	13	neurosurgical	neurosurgical	JJ
cord-009417-458rrhcm	174	14	patients	patient	NNS
cord-009417-458rrhcm	174	15	,	,	,
cord-009417-458rrhcm	174	16	may	may	MD
cord-009417-458rrhcm	174	17	need	need	VB
cord-009417-458rrhcm	174	18	to	to	TO
cord-009417-458rrhcm	174	19	be	be	VB
cord-009417-458rrhcm	174	20	maintained	maintain	VBN
cord-009417-458rrhcm	174	21	at	at	IN
cord-009417-458rrhcm	174	22	counts	count	NNS
cord-009417-458rrhcm	174	23	of	of	IN
cord-009417-458rrhcm	174	24	80	80	CD
cord-009417-458rrhcm	174	25	to	to	TO
cord-009417-458rrhcm	174	26	100	100	CD
cord-009417-458rrhcm	174	27	×	×	NN
cord-009417-458rrhcm	175	1	10	10	CD
cord-009417-458rrhcm	175	2	9	9	CD
cord-009417-458rrhcm	175	3	/L.	/L.	.
cord-009417-458rrhcm	175	4	Patients	patient	NNS
cord-009417-458rrhcm	175	5	without	without	IN
cord-009417-458rrhcm	175	6	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	175	7	who	who	WP
cord-009417-458rrhcm	175	8	have	have	VBP
cord-009417-458rrhcm	175	9	platelet	platelet	NN
cord-009417-458rrhcm	175	10	counts	count	NNS
cord-009417-458rrhcm	175	11	of	of	IN
cord-009417-458rrhcm	175	12	5	5	CD
cord-009417-458rrhcm	175	13	×	×	NN
cord-009417-458rrhcm	175	14	10	10	CD
cord-009417-458rrhcm	175	15	9	9	CD
cord-009417-458rrhcm	175	16	/L	/L	,
cord-009417-458rrhcm	175	17	or	or	CC
cord-009417-458rrhcm	175	18	lower	low	JJR
cord-009417-458rrhcm	175	19	appear	appear	VB
cord-009417-458rrhcm	175	20	to	to	TO
cord-009417-458rrhcm	175	21	be	be	VB
cord-009417-458rrhcm	175	22	at	at	IN
cord-009417-458rrhcm	175	23	increased	increase	VBN
cord-009417-458rrhcm	175	24	risk	risk	NN
cord-009417-458rrhcm	175	25	for	for	IN
cord-009417-458rrhcm	175	26	signifi	signifi	NNP
cord-009417-458rrhcm	176	1	ca	can	MD
cord-009417-458rrhcm	176	2	nt	not	RB
cord-009417-458rrhcm	176	3	hemorrhage	hemorrhage	VB
cord-009417-458rrhcm	176	4	.	.	.
cord-009417-458rrhcm	177	1	Indications	indication	NNS
cord-009417-458rrhcm	177	2	for	for	IN
cord-009417-458rrhcm	177	3	transfusion	transfusion	NN
cord-009417-458rrhcm	177	4	to	to	IN
cord-009417-458rrhcm	177	5	patients	patient	NNS
cord-009417-458rrhcm	177	6	with	with	IN
cord-009417-458rrhcm	177	7	counts	count	NNS
cord-009417-458rrhcm	177	8	above	above	IN
cord-009417-458rrhcm	177	9	10	10	CD
cord-009417-458rrhcm	177	10	×	×	NN
cord-009417-458rrhcm	177	11	10	10	CD
cord-009417-458rrhcm	177	12	9	9	CD
cord-009417-458rrhcm	177	13	/L	/L	.
cord-009417-458rrhcm	177	14	are	be	VBP
cord-009417-458rrhcm	177	15	less	less	RBR
cord-009417-458rrhcm	177	16	well	well	RB
cord-009417-458rrhcm	177	17	established	establish	VBN
cord-009417-458rrhcm	177	18	;	;	:
cord-009417-458rrhcm	177	19	thus	thus	RB
cord-009417-458rrhcm	177	20	,	,	,
cord-009417-458rrhcm	177	21	the	the	DT
cord-009417-458rrhcm	177	22	majority	majority	NN
cord-009417-458rrhcm	177	23	of	of	IN
cord-009417-458rrhcm	177	24	guidelines	guideline	NNS
cord-009417-458rrhcm	177	25	propose	propose	VBP
cord-009417-458rrhcm	177	26	prophylactic	prophylactic	JJ
cord-009417-458rrhcm	177	27	platelet	platelet	NN
cord-009417-458rrhcm	177	28	transfusion	transfusion	NN
cord-009417-458rrhcm	177	29	to	to	TO
cord-009417-458rrhcm	177	30	prevent	prevent	VB
cord-009417-458rrhcm	177	31	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	177	32	at	at	IN
cord-009417-458rrhcm	177	33	a	a	DT
cord-009417-458rrhcm	177	34	threshold	threshold	NN
cord-009417-458rrhcm	177	35	of	of	IN
cord-009417-458rrhcm	177	36	10	10	CD
cord-009417-458rrhcm	177	37	×	×	NN
cord-009417-458rrhcm	177	38	10	10	CD
cord-009417-458rrhcm	177	39	9	9	CD
cord-009417-458rrhcm	178	1	/L.	/L.	.
cord-009417-458rrhcm	179	1	The	the	DT
cord-009417-458rrhcm	179	2	bleeding	bleeding	JJ
cord-009417-458rrhcm	179	3	time	time	NN
cord-009417-458rrhcm	179	4	is	be	VBZ
cord-009417-458rrhcm	179	5	not	not	RB
cord-009417-458rrhcm	179	6	a	a	DT
cord-009417-458rrhcm	179	7	useful	useful	JJ
cord-009417-458rrhcm	179	8	procedure	procedure	NN
cord-009417-458rrhcm	179	9	in	in	IN
cord-009417-458rrhcm	179	10	this	this	DT
cord-009417-458rrhcm	179	11	situation	situation	NN
cord-009417-458rrhcm	179	12	because	because	IN
cord-009417-458rrhcm	179	13	it	-PRON-	PRP
cord-009417-458rrhcm	179	14	is	be	VBZ
cord-009417-458rrhcm	179	15	usually	usually	RB
cord-009417-458rrhcm	179	16	prolonged	prolong	VBN
cord-009417-458rrhcm	179	17	at	at	IN
cord-009417-458rrhcm	179	18	counts	count	NNS
cord-009417-458rrhcm	179	19	below	below	IN
cord-009417-458rrhcm	179	20	80	80	CD
cord-009417-458rrhcm	179	21	×	×	NN
cord-009417-458rrhcm	179	22	10	10	CD
cord-009417-458rrhcm	179	23	9	9	CD
cord-009417-458rrhcm	179	24	/L	/l	CD
cord-009417-458rrhcm	179	25	,	,	,
cord-009417-458rrhcm	179	26	may	may	MD
cord-009417-458rrhcm	179	27	be	be	VB
cord-009417-458rrhcm	179	28	insuffi	insuffi	NNP
cord-009417-458rrhcm	179	29	ciently	ciently	RB
cord-009417-458rrhcm	179	30	reproducible	reproducible	JJ
cord-009417-458rrhcm	179	31	,	,	,
cord-009417-458rrhcm	179	32	and	and	CC
cord-009417-458rrhcm	179	33	correlates	correlate	VBZ
cord-009417-458rrhcm	179	34	poorly	poorly	RB
cord-009417-458rrhcm	179	35	with	with	IN
cord-009417-458rrhcm	179	36	the	the	DT
cord-009417-458rrhcm	179	37	risk	risk	NN
cord-009417-458rrhcm	179	38	for	for	IN
cord-009417-458rrhcm	179	39	bleeding	bleed	VBG
cord-009417-458rrhcm	179	40	.	.	.
cord-009417-458rrhcm	180	1	37	37	CD
cord-009417-458rrhcm	180	2	Patients	patient	NNS
cord-009417-458rrhcm	180	3	undergoing	undergo	VBG
cord-009417-458rrhcm	180	4	cardiac	cardiac	JJ
cord-009417-458rrhcm	180	5	bypass	bypass	NN
cord-009417-458rrhcm	180	6	surgery	surgery	NN
cord-009417-458rrhcm	180	7	experience	experience	NN
cord-009417-458rrhcm	180	8	a	a	DT
cord-009417-458rrhcm	180	9	drop	drop	NN
cord-009417-458rrhcm	180	10	in	in	IN
cord-009417-458rrhcm	180	11	platelet	platelet	NN
cord-009417-458rrhcm	180	12	count	count	NN
cord-009417-458rrhcm	180	13	and	and	CC
cord-009417-458rrhcm	180	14	often	often	RB
cord-009417-458rrhcm	180	15	acquire	acquire	VBP
cord-009417-458rrhcm	180	16	a	a	DT
cord-009417-458rrhcm	180	17	transient	transient	JJ
cord-009417-458rrhcm	180	18	platelet	platelet	NN
cord-009417-458rrhcm	180	19	functional	functional	JJ
cord-009417-458rrhcm	180	20	defect	defect	NN
cord-009417-458rrhcm	180	21	from	from	IN
cord-009417-458rrhcm	180	22	damage	damage	NN
cord-009417-458rrhcm	180	23	associated	associate	VBN
cord-009417-458rrhcm	180	24	with	with	IN
cord-009417-458rrhcm	180	25	the	the	DT
cord-009417-458rrhcm	180	26	bypass	bypass	NN
cord-009417-458rrhcm	180	27	apparatus	apparatus	NN
cord-009417-458rrhcm	180	28	.	.	.
cord-009417-458rrhcm	181	1	38	38	CD
cord-009417-458rrhcm	181	2	Most	Most	JJS
cord-009417-458rrhcm	181	3	patients	patient	NNS
cord-009417-458rrhcm	181	4	do	do	VBP
cord-009417-458rrhcm	181	5	not	not	RB
cord-009417-458rrhcm	181	6	experience	experience	VB
cord-009417-458rrhcm	181	7	platelet	platelet	NN
cord-009417-458rrhcm	181	8	-	-	HYPH
cord-009417-458rrhcm	181	9	associated	associate	VBN
cord-009417-458rrhcm	181	10	bleeding	bleeding	NN
cord-009417-458rrhcm	181	11	,	,	,
cord-009417-458rrhcm	181	12	however	however	RB
cord-009417-458rrhcm	181	13	,	,	,
cord-009417-458rrhcm	181	14	so	so	RB
cord-009417-458rrhcm	181	15	prophylactic	prophylactic	JJ
cord-009417-458rrhcm	181	16	transfusion	transfusion	NN
cord-009417-458rrhcm	181	17	in	in	IN
cord-009417-458rrhcm	181	18	the	the	DT
cord-009417-458rrhcm	181	19	absence	absence	NN
cord-009417-458rrhcm	181	20	of	of	IN
cord-009417-458rrhcm	181	21	bleeding	bleeding	NN
cord-009417-458rrhcm	181	22	is	be	VBZ
cord-009417-458rrhcm	181	23	not	not	RB
cord-009417-458rrhcm	181	24	warranted	warrant	VBN
cord-009417-458rrhcm	181	25	.	.	.
cord-009417-458rrhcm	182	1	In	in	IN
cord-009417-458rrhcm	182	2	a	a	DT
cord-009417-458rrhcm	182	3	patient	patient	NN
cord-009417-458rrhcm	182	4	who	who	WP
cord-009417-458rrhcm	182	5	continues	continue	VBZ
cord-009417-458rrhcm	182	6	to	to	TO
cord-009417-458rrhcm	182	7	bleed	bleed	VB
cord-009417-458rrhcm	182	8	postoperatively	postoperatively	RB
cord-009417-458rrhcm	182	9	,	,	,
cord-009417-458rrhcm	182	10	more	more	RBR
cord-009417-458rrhcm	182	11	likely	likely	JJ
cord-009417-458rrhcm	182	12	causes	cause	NNS
cord-009417-458rrhcm	182	13	are	be	VBP
cord-009417-458rrhcm	182	14	a	a	DT
cord-009417-458rrhcm	182	15	localized	localize	VBN
cord-009417-458rrhcm	182	16	,	,	,
cord-009417-458rrhcm	182	17	surgically	surgically	RB
cord-009417-458rrhcm	182	18	correctable	correctable	JJ
cord-009417-458rrhcm	182	19	lesion	lesion	NN
cord-009417-458rrhcm	182	20	or	or	CC
cord-009417-458rrhcm	182	21	failure	failure	NN
cord-009417-458rrhcm	182	22	to	to	TO
cord-009417-458rrhcm	182	23	reverse	reverse	VB
cord-009417-458rrhcm	182	24	heparinization	heparinization	NN
cord-009417-458rrhcm	182	25	.	.	.
cord-009417-458rrhcm	183	1	If	if	IN
cord-009417-458rrhcm	183	2	these	these	DT
cord-009417-458rrhcm	183	3	conditions	condition	NNS
cord-009417-458rrhcm	183	4	are	be	VBP
cord-009417-458rrhcm	183	5	excluded	exclude	VBN
cord-009417-458rrhcm	183	6	,	,	,
cord-009417-458rrhcm	183	7	empiric	empiric	JJ
cord-009417-458rrhcm	183	8	transfusion	transfusion	NN
cord-009417-458rrhcm	183	9	of	of	IN
cord-009417-458rrhcm	183	10	platelets	platelet	NNS
cord-009417-458rrhcm	183	11	may	may	MD
cord-009417-458rrhcm	183	12	be	be	VB
cord-009417-458rrhcm	183	13	justifi	justifi	NNP
cord-009417-458rrhcm	183	14	ed	ed	NN
cord-009417-458rrhcm	183	15	.	.	.
cord-009417-458rrhcm	184	1	Patients	patient	NNS
cord-009417-458rrhcm	184	2	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	184	3	by	by	IN
cord-009417-458rrhcm	184	4	virtue	virtue	NN
cord-009417-458rrhcm	184	5	of	of	IN
cord-009417-458rrhcm	184	6	immunologic	immunologic	JJ
cord-009417-458rrhcm	184	7	destructive	destructive	JJ
cord-009417-458rrhcm	184	8	processes	process	NNS
cord-009417-458rrhcm	184	9	such	such	JJ
cord-009417-458rrhcm	184	10	as	as	IN
cord-009417-458rrhcm	184	11	idiopathic	idiopathic	JJ
cord-009417-458rrhcm	184	12	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	184	13	purpura	purpura	NN
cord-009417-458rrhcm	184	14	(	(	-LRB-
cord-009417-458rrhcm	184	15	ITP	ITP	NNP
cord-009417-458rrhcm	184	16	)	)	-RRB-
cord-009417-458rrhcm	184	17	receive	receive	VBP
cord-009417-458rrhcm	184	18	little	little	JJ
cord-009417-458rrhcm	184	19	benefi	benefi	NNP
cord-009417-458rrhcm	184	20	t	t	NN
cord-009417-458rrhcm	184	21	from	from	IN
cord-009417-458rrhcm	184	22	platelet	platelet	NN
cord-009417-458rrhcm	184	23	transfusions	transfusion	NNS
cord-009417-458rrhcm	184	24	because	because	IN
cord-009417-458rrhcm	184	25	the	the	DT
cord-009417-458rrhcm	184	26	transfused	transfuse	VBN
cord-009417-458rrhcm	184	27	platelets	platelet	NNS
cord-009417-458rrhcm	184	28	are	be	VBP
cord-009417-458rrhcm	184	29	rapidly	rapidly	RB
cord-009417-458rrhcm	184	30	removed	remove	VBN
cord-009417-458rrhcm	184	31	from	from	IN
cord-009417-458rrhcm	184	32	the	the	DT
cord-009417-458rrhcm	184	33	circulation	circulation	NN
cord-009417-458rrhcm	184	34	.	.	.
cord-009417-458rrhcm	185	1	In	in	IN
cord-009417-458rrhcm	185	2	the	the	DT
cord-009417-458rrhcm	185	3	event	event	NN
cord-009417-458rrhcm	185	4	of	of	IN
cord-009417-458rrhcm	185	5	life	life	NN
cord-009417-458rrhcm	185	6	-	-	HYPH
cord-009417-458rrhcm	185	7	threatening	threaten	VBG
cord-009417-458rrhcm	185	8	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	185	9	or	or	CC
cord-009417-458rrhcm	185	10	an	an	DT
cord-009417-458rrhcm	185	11	extensive	extensive	JJ
cord-009417-458rrhcm	185	12	surgical	surgical	JJ
cord-009417-458rrhcm	185	13	procedure	procedure	NN
cord-009417-458rrhcm	185	14	,	,	,
cord-009417-458rrhcm	185	15	transfusion	transfusion	NN
cord-009417-458rrhcm	185	16	may	may	MD
cord-009417-458rrhcm	185	17	prove	prove	VB
cord-009417-458rrhcm	185	18	benefi	benefi	NNP
cord-009417-458rrhcm	185	19	cial	cial	NN
cord-009417-458rrhcm	185	20	for	for	IN
cord-009417-458rrhcm	185	21	its	-PRON-	PRP$
cord-009417-458rrhcm	185	22	short	short	JJ
cord-009417-458rrhcm	185	23	-	-	HYPH
cord-009417-458rrhcm	185	24	term	term	NN
cord-009417-458rrhcm	185	25	effect	effect	NN
cord-009417-458rrhcm	185	26	.	.	.
cord-009417-458rrhcm	186	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	186	2	may	may	MD
cord-009417-458rrhcm	186	3	be	be	VB
cord-009417-458rrhcm	186	4	accomplished	accomplish	VBN
cord-009417-458rrhcm	186	5	effectively	effectively	RB
cord-009417-458rrhcm	186	6	by	by	IN
cord-009417-458rrhcm	186	7	pretreatment	pretreatment	NN
cord-009417-458rrhcm	186	8	with	with	IN
cord-009417-458rrhcm	186	9	high	high	JJ
cord-009417-458rrhcm	186	10	-	-	HYPH
cord-009417-458rrhcm	186	11	dose	dose	NN
cord-009417-458rrhcm	186	12	immunoglobulin	immunoglobulin	NN
cord-009417-458rrhcm	186	13	or	or	CC
cord-009417-458rrhcm	186	14	high	high	JJ
cord-009417-458rrhcm	186	15	-	-	HYPH
cord-009417-458rrhcm	186	16	dose	dose	NN
cord-009417-458rrhcm	186	17	anti	anti	JJ
cord-009417-458rrhcm	186	18	-	-	JJ
cord-009417-458rrhcm	186	19	D	d	JJ
cord-009417-458rrhcm	186	20	antiserum	antiserum	NN
cord-009417-458rrhcm	186	21	(	(	-LRB-
cord-009417-458rrhcm	186	22	RhIG	RhIG	NNP
cord-009417-458rrhcm	186	23	)	)	-RRB-
cord-009417-458rrhcm	186	24	.	.	.
cord-009417-458rrhcm	187	1	39	39	CD
cord-009417-458rrhcm	187	2	,	,	,
cord-009417-458rrhcm	187	3	40	40	CD
cord-009417-458rrhcm	187	4	Platelet	platelet	NN
cord-009417-458rrhcm	187	5	transfusion	transfusion	NN
cord-009417-458rrhcm	187	6	has	have	VBZ
cord-009417-458rrhcm	187	7	been	be	VBN
cord-009417-458rrhcm	187	8	reported	report	VBN
cord-009417-458rrhcm	187	9	to	to	TO
cord-009417-458rrhcm	187	10	be	be	VB
cord-009417-458rrhcm	187	11	deleterious	deleterious	JJ
cord-009417-458rrhcm	187	12	in	in	IN
cord-009417-458rrhcm	187	13	thrombotic	thrombotic	JJ
cord-009417-458rrhcm	187	14	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	187	15	purpura	purpura	NN
cord-009417-458rrhcm	187	16	(	(	-LRB-
cord-009417-458rrhcm	187	17	TTP	TTP	NNP
cord-009417-458rrhcm	187	18	)	)	-RRB-
cord-009417-458rrhcm	187	19	,	,	,
cord-009417-458rrhcm	187	20	41	41	CD
cord-009417-458rrhcm	187	21	in	in	IN
cord-009417-458rrhcm	187	22	the	the	DT
cord-009417-458rrhcm	187	23	related	related	JJ
cord-009417-458rrhcm	187	24	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	187	25	-	-	HYPH
cord-009417-458rrhcm	187	26	uremic	uremic	NN
cord-009417-458rrhcm	187	27	syndrome	syndrome	NN
cord-009417-458rrhcm	187	28	,	,	,
cord-009417-458rrhcm	187	29	and	and	CC
cord-009417-458rrhcm	187	30	in	in	IN
cord-009417-458rrhcm	187	31	heparin	heparin	NN
cord-009417-458rrhcm	187	32	-	-	HYPH
cord-009417-458rrhcm	187	33	induced	induce	VBN
cord-009417-458rrhcm	187	34	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	187	35	.	.	.
cord-009417-458rrhcm	188	1	Cautious	cautious	JJ
cord-009417-458rrhcm	188	2	administration	administration	NN
cord-009417-458rrhcm	188	3	,	,	,
cord-009417-458rrhcm	188	4	in	in	IN
cord-009417-458rrhcm	188	5	cases	case	NNS
cord-009417-458rrhcm	188	6	of	of	IN
cord-009417-458rrhcm	188	7	life	life	NN
cord-009417-458rrhcm	188	8	-	-	HYPH
cord-009417-458rrhcm	188	9	threatening	threaten	VBG
cord-009417-458rrhcm	188	10	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	188	11	bleeding	bleed	VBG
cord-009417-458rrhcm	188	12	only	only	RB
cord-009417-458rrhcm	188	13	,	,	,
cord-009417-458rrhcm	188	14	is	be	VBZ
cord-009417-458rrhcm	188	15	prudent	prudent	JJ
cord-009417-458rrhcm	188	16	.	.	.
cord-009417-458rrhcm	189	1	Prophylactic	prophylactic	JJ
cord-009417-458rrhcm	189	2	platelet	platelet	NN
cord-009417-458rrhcm	189	3	transfusion	transfusion	NN
cord-009417-458rrhcm	189	4	for	for	IN
cord-009417-458rrhcm	189	5	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	189	6	secondary	secondary	JJ
cord-009417-458rrhcm	189	7	to	to	IN
cord-009417-458rrhcm	189	8	underproduction	underproduction	NN
cord-009417-458rrhcm	189	9	remains	remain	VBZ
cord-009417-458rrhcm	189	10	controversial	controversial	JJ
cord-009417-458rrhcm	189	11	.	.	.
cord-009417-458rrhcm	190	1	The	the	DT
cord-009417-458rrhcm	190	2	common	common	JJ
cord-009417-458rrhcm	190	3	practice	practice	NN
cord-009417-458rrhcm	190	4	of	of	IN
cord-009417-458rrhcm	190	5	transfusion	transfusion	NN
cord-009417-458rrhcm	190	6	to	to	TO
cord-009417-458rrhcm	190	7	maintain	maintain	VB
cord-009417-458rrhcm	190	8	the	the	DT
cord-009417-458rrhcm	190	9	platelet	platelet	NN
cord-009417-458rrhcm	190	10	count	count	NN
cord-009417-458rrhcm	190	11	above	above	IN
cord-009417-458rrhcm	190	12	20	20	CD
cord-009417-458rrhcm	190	13	×	×	NN
cord-009417-458rrhcm	191	1	10	10	CD
cord-009417-458rrhcm	191	2	9	9	CD
cord-009417-458rrhcm	191	3	/L	/L	.
cord-009417-458rrhcm	191	4	derives	derive	VBZ
cord-009417-458rrhcm	191	5	from	from	IN
cord-009417-458rrhcm	191	6	data	datum	NNS
cord-009417-458rrhcm	191	7	published	publish	VBN
cord-009417-458rrhcm	191	8	in	in	IN
cord-009417-458rrhcm	191	9	1962	1962	CD
cord-009417-458rrhcm	191	10	,	,	,
cord-009417-458rrhcm	191	11	which	which	WDT
cord-009417-458rrhcm	191	12	demonstrated	demonstrate	VBD
cord-009417-458rrhcm	191	13	an	an	DT
cord-009417-458rrhcm	191	14	increase	increase	NN
cord-009417-458rrhcm	191	15	in	in	IN
cord-009417-458rrhcm	191	16	spontaneous	spontaneous	JJ
cord-009417-458rrhcm	191	17	bleeding	bleeding	NN
cord-009417-458rrhcm	191	18	in	in	IN
cord-009417-458rrhcm	191	19	leukemic	leukemic	JJ
cord-009417-458rrhcm	191	20	patients	patient	NNS
cord-009417-458rrhcm	191	21	at	at	IN
cord-009417-458rrhcm	191	22	that	that	DT
cord-009417-458rrhcm	191	23	level	level	NN
cord-009417-458rrhcm	191	24	.	.	.
cord-009417-458rrhcm	192	1	42	42	CD
cord-009417-458rrhcm	193	1	However	however	RB
cord-009417-458rrhcm	193	2	,	,	,
cord-009417-458rrhcm	193	3	critical	critical	JJ
cord-009417-458rrhcm	193	4	evaluation	evaluation	NN
cord-009417-458rrhcm	193	5	of	of	IN
cord-009417-458rrhcm	193	6	the	the	DT
cord-009417-458rrhcm	193	7	data	data	NN
cord-009417-458rrhcm	193	8	reveals	reveal	VBZ
cord-009417-458rrhcm	193	9	that	that	IN
cord-009417-458rrhcm	193	10	serious	serious	JJ
cord-009417-458rrhcm	193	11	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	193	12	was	be	VBD
cord-009417-458rrhcm	193	13	not	not	RB
cord-009417-458rrhcm	193	14	greatly	greatly	RB
cord-009417-458rrhcm	193	15	increased	increase	VBN
cord-009417-458rrhcm	193	16	until	until	IN
cord-009417-458rrhcm	193	17	counts	count	NNS
cord-009417-458rrhcm	193	18	fell	fall	VBD
cord-009417-458rrhcm	193	19	to	to	IN
cord-009417-458rrhcm	193	20	5	5	CD
cord-009417-458rrhcm	193	21	×	×	NN
cord-009417-458rrhcm	193	22	10	10	CD
cord-009417-458rrhcm	193	23	9	9	CD
cord-009417-458rrhcm	193	24	/L	/L	,
cord-009417-458rrhcm	193	25	or	or	CC
cord-009417-458rrhcm	193	26	lower	low	JJR
cord-009417-458rrhcm	193	27	and	and	CC
cord-009417-458rrhcm	193	28	that	that	IN
cord-009417-458rrhcm	193	29	these	these	DT
cord-009417-458rrhcm	193	30	patients	patient	NNS
cord-009417-458rrhcm	193	31	received	receive	VBD
cord-009417-458rrhcm	193	32	aspirin	aspirin	NN
cord-009417-458rrhcm	193	33	for	for	IN
cord-009417-458rrhcm	193	34	fever	fever	NN
cord-009417-458rrhcm	193	35	,	,	,
cord-009417-458rrhcm	193	36	which	which	WDT
cord-009417-458rrhcm	193	37	might	may	MD
cord-009417-458rrhcm	193	38	have	have	VB
cord-009417-458rrhcm	193	39	compromised	compromise	VBN
cord-009417-458rrhcm	193	40	platelet	platelet	NN
cord-009417-458rrhcm	193	41	function	function	NN
cord-009417-458rrhcm	193	42	and	and	CC
cord-009417-458rrhcm	193	43	enhanced	enhance	VBD
cord-009417-458rrhcm	193	44	the	the	DT
cord-009417-458rrhcm	193	45	bleeding	bleeding	NN
cord-009417-458rrhcm	193	46	.	.	.
cord-009417-458rrhcm	194	1	A	a	DT
cord-009417-458rrhcm	194	2	somewhat	somewhat	RB
cord-009417-458rrhcm	194	3	more	more	RBR
cord-009417-458rrhcm	194	4	recent	recent	JJ
cord-009417-458rrhcm	194	5	study	study	NN
cord-009417-458rrhcm	194	6	quantitating	quantitate	VBG
cord-009417-458rrhcm	194	7	stool	stool	NN
cord-009417-458rrhcm	194	8	blood	blood	NN
cord-009417-458rrhcm	194	9	loss	loss	NN
cord-009417-458rrhcm	194	10	in	in	IN
cord-009417-458rrhcm	194	11	aplastic	aplastic	JJ
cord-009417-458rrhcm	194	12	anemia	anemia	NN
cord-009417-458rrhcm	194	13	patients	patient	NNS
cord-009417-458rrhcm	194	14	defi	defi	NNP
cord-009417-458rrhcm	194	15	ned	ned	NNP
cord-009417-458rrhcm	194	16	a	a	DT
cord-009417-458rrhcm	194	17	bleeding	bleed	VBG
cord-009417-458rrhcm	194	18	threshold	threshold	NN
cord-009417-458rrhcm	194	19	at	at	IN
cord-009417-458rrhcm	194	20	platelet	platelet	NN
cord-009417-458rrhcm	194	21	counts	count	NNS
cord-009417-458rrhcm	194	22	of	of	IN
cord-009417-458rrhcm	194	23	5	5	CD
cord-009417-458rrhcm	194	24	to	to	TO
cord-009417-458rrhcm	194	25	10	10	CD
cord-009417-458rrhcm	194	26	×	×	NN
cord-009417-458rrhcm	194	27	10	10	CD
cord-009417-458rrhcm	194	28	9	9	CD
cord-009417-458rrhcm	195	1	/L.	/l.	NN
cord-009417-458rrhcm	195	2	43	43	CD
cord-009417-458rrhcm	196	1	A	a	DT
cord-009417-458rrhcm	196	2	prospective	prospective	JJ
cord-009417-458rrhcm	196	3	study	study	NN
cord-009417-458rrhcm	196	4	of	of	IN
cord-009417-458rrhcm	196	5	a	a	DT
cord-009417-458rrhcm	196	6	more	more	RBR
cord-009417-458rrhcm	196	7	conservative	conservative	JJ
cord-009417-458rrhcm	196	8	transfusion	transfusion	NN
cord-009417-458rrhcm	196	9	protocol	protocol	NN
cord-009417-458rrhcm	196	10	found	find	VBD
cord-009417-458rrhcm	196	11	that	that	IN
cord-009417-458rrhcm	196	12	major	major	JJ
cord-009417-458rrhcm	196	13	bleeding	bleed	VBG
cord-009417-458rrhcm	196	14	episodes	episode	NNS
cord-009417-458rrhcm	196	15	occurred	occur	VBD
cord-009417-458rrhcm	196	16	on	on	IN
cord-009417-458rrhcm	196	17	1.9	1.9	CD
cord-009417-458rrhcm	196	18	%	%	NN
cord-009417-458rrhcm	196	19	of	of	IN
cord-009417-458rrhcm	196	20	days	day	NNS
cord-009417-458rrhcm	196	21	with	with	IN
cord-009417-458rrhcm	196	22	counts	count	NNS
cord-009417-458rrhcm	196	23	of	of	IN
cord-009417-458rrhcm	196	24	less	less	JJR
cord-009417-458rrhcm	196	25	than	than	IN
cord-009417-458rrhcm	196	26	10	10	CD
cord-009417-458rrhcm	196	27	×	×	NN
cord-009417-458rrhcm	196	28	10	10	CD
cord-009417-458rrhcm	196	29	9	9	CD
cord-009417-458rrhcm	196	30	/L	/L	.
cord-009417-458rrhcm	196	31	and	and	CC
cord-009417-458rrhcm	196	32	on	on	IN
cord-009417-458rrhcm	196	33	only	only	RB
cord-009417-458rrhcm	196	34	0.07	0.07	CD
cord-009417-458rrhcm	196	35	%	%	NN
cord-009417-458rrhcm	196	36	of	of	IN
cord-009417-458rrhcm	196	37	days	day	NNS
cord-009417-458rrhcm	196	38	with	with	IN
cord-009417-458rrhcm	196	39	counts	count	NNS
cord-009417-458rrhcm	196	40	of	of	IN
cord-009417-458rrhcm	196	41	10	10	CD
cord-009417-458rrhcm	196	42	to	to	TO
cord-009417-458rrhcm	196	43	20	20	CD
cord-009417-458rrhcm	196	44	×	×	NN
cord-009417-458rrhcm	196	45	10	10	CD
cord-009417-458rrhcm	196	46	9	9	CD
cord-009417-458rrhcm	196	47	/L.	/l.	CD
cord-009417-458rrhcm	196	48	44	44	CD
cord-009417-458rrhcm	197	1	The	the	DT
cord-009417-458rrhcm	197	2	trigger	trigger	NN
cord-009417-458rrhcm	197	3	for	for	IN
cord-009417-458rrhcm	197	4	prophylactic	prophylactic	JJ
cord-009417-458rrhcm	197	5	platelet	platelet	NN
cord-009417-458rrhcm	197	6	transfusion	transfusion	NN
cord-009417-458rrhcm	197	7	in	in	IN
cord-009417-458rrhcm	197	8	the	the	DT
cord-009417-458rrhcm	197	9	5	5	CD
cord-009417-458rrhcm	197	10	to	to	TO
cord-009417-458rrhcm	197	11	10	10	CD
cord-009417-458rrhcm	197	12	×	×	NN
cord-009417-458rrhcm	197	13	10	10	CD
cord-009417-458rrhcm	197	14	9	9	CD
cord-009417-458rrhcm	197	15	/L	/l	CD
cord-009417-458rrhcm	197	16	range	range	NN
cord-009417-458rrhcm	197	17	,	,	,
cord-009417-458rrhcm	197	18	however	however	RB
cord-009417-458rrhcm	197	19	,	,	,
cord-009417-458rrhcm	197	20	applies	apply	VBZ
cord-009417-458rrhcm	197	21	primarily	primarily	RB
cord-009417-458rrhcm	197	22	to	to	IN
cord-009417-458rrhcm	197	23	stable	stable	JJ
cord-009417-458rrhcm	197	24	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	197	25	patients	patient	NNS
cord-009417-458rrhcm	197	26	.	.	.
cord-009417-458rrhcm	198	1	Factors	factor	NNS
cord-009417-458rrhcm	198	2	such	such	JJ
cord-009417-458rrhcm	198	3	as	as	IN
cord-009417-458rrhcm	198	4	fever	fever	NN
cord-009417-458rrhcm	198	5	,	,	,
cord-009417-458rrhcm	198	6	use	use	NN
cord-009417-458rrhcm	198	7	of	of	IN
cord-009417-458rrhcm	198	8	anticoagulant	anticoagulant	JJ
cord-009417-458rrhcm	198	9	or	or	CC
cord-009417-458rrhcm	198	10	antiplatelet	antiplatelet	JJ
cord-009417-458rrhcm	198	11	drugs	drug	NNS
cord-009417-458rrhcm	198	12	,	,	,
cord-009417-458rrhcm	198	13	and	and	CC
cord-009417-458rrhcm	198	14	invasive	invasive	JJ
cord-009417-458rrhcm	198	15	procedures	procedure	NNS
cord-009417-458rrhcm	198	16	must	must	MD
cord-009417-458rrhcm	198	17	be	be	VB
cord-009417-458rrhcm	198	18	considered	consider	VBN
cord-009417-458rrhcm	198	19	when	when	WRB
cord-009417-458rrhcm	198	20	generating	generate	VBG
cord-009417-458rrhcm	198	21	a	a	DT
cord-009417-458rrhcm	198	22	treatment	treatment	NN
cord-009417-458rrhcm	198	23	plan	plan	NN
cord-009417-458rrhcm	198	24	for	for	IN
cord-009417-458rrhcm	198	25	individual	individual	JJ
cord-009417-458rrhcm	198	26	patients	patient	NNS
cord-009417-458rrhcm	198	27	.	.	.
cord-009417-458rrhcm	199	1	Patients	patient	NNS
cord-009417-458rrhcm	199	2	experiencing	experience	VBG
cord-009417-458rrhcm	199	3	rapid	rapid	JJ
cord-009417-458rrhcm	199	4	drops	drop	NNS
cord-009417-458rrhcm	199	5	in	in	IN
cord-009417-458rrhcm	199	6	platelet	platelet	NN
cord-009417-458rrhcm	199	7	count	count	NN
cord-009417-458rrhcm	199	8	may	may	MD
cord-009417-458rrhcm	199	9	be	be	VB
cord-009417-458rrhcm	199	10	at	at	IN
cord-009417-458rrhcm	199	11	greater	great	JJR
cord-009417-458rrhcm	199	12	risk	risk	NN
cord-009417-458rrhcm	199	13	than	than	IN
cord-009417-458rrhcm	199	14	those	those	DT
cord-009417-458rrhcm	199	15	at	at	IN
cord-009417-458rrhcm	199	16	steady	steady	JJ
cord-009417-458rrhcm	199	17	state	state	NN
cord-009417-458rrhcm	199	18	and	and	CC
cord-009417-458rrhcm	199	19	thus	thus	RB
cord-009417-458rrhcm	199	20	may	may	MD
cord-009417-458rrhcm	199	21	benefi	benefi	VB
cord-009417-458rrhcm	199	22	t	t	NN
cord-009417-458rrhcm	199	23	from	from	IN
cord-009417-458rrhcm	199	24	transfusion	transfusion	NN
cord-009417-458rrhcm	199	25	at	at	IN
cord-009417-458rrhcm	199	26	higher	high	JJR
cord-009417-458rrhcm	199	27	counts	count	NNS
cord-009417-458rrhcm	199	28	.	.	.
cord-009417-458rrhcm	200	1	Benefi	Benefi	NNP
cord-009417-458rrhcm	200	2	ts	ts	XX
cord-009417-458rrhcm	200	3	to	to	IN
cord-009417-458rrhcm	200	4	the	the	DT
cord-009417-458rrhcm	200	5	patient	patient	NN
cord-009417-458rrhcm	200	6	with	with	IN
cord-009417-458rrhcm	200	7	more	more	RBR
cord-009417-458rrhcm	200	8	judicious	judicious	JJ
cord-009417-458rrhcm	200	9	use	use	NN
cord-009417-458rrhcm	200	10	of	of	IN
cord-009417-458rrhcm	200	11	platelet	platelet	NN
cord-009417-458rrhcm	200	12	transfusion	transfusion	NN
cord-009417-458rrhcm	200	13	include	include	VBP
cord-009417-458rrhcm	200	14	decreased	decrease	VBD
cord-009417-458rrhcm	200	15	donor	donor	NN
cord-009417-458rrhcm	200	16	exposure	exposure	NN
cord-009417-458rrhcm	200	17	,	,	,
cord-009417-458rrhcm	200	18	which	which	WDT
cord-009417-458rrhcm	200	19	lessens	lessen	VBZ
cord-009417-458rrhcm	200	20	the	the	DT
cord-009417-458rrhcm	200	21	risk	risk	NN
cord-009417-458rrhcm	200	22	of	of	IN
cord-009417-458rrhcm	200	23	transfusion	transfusion	NN
cord-009417-458rrhcm	200	24	-	-	HYPH
cord-009417-458rrhcm	200	25	transmitted	transmit	VBN
cord-009417-458rrhcm	200	26	disease	disease	NN
cord-009417-458rrhcm	200	27	;	;	:
cord-009417-458rrhcm	200	28	fewer	few	JJR
cord-009417-458rrhcm	200	29	febrile	febrile	JJ
cord-009417-458rrhcm	200	30	and	and	CC
cord-009417-458rrhcm	200	31	allergic	allergic	JJ
cord-009417-458rrhcm	200	32	reactions	reaction	NNS
cord-009417-458rrhcm	200	33	that	that	WDT
cord-009417-458rrhcm	200	34	may	may	MD
cord-009417-458rrhcm	200	35	complicate	complicate	VB
cord-009417-458rrhcm	200	36	the	the	DT
cord-009417-458rrhcm	200	37	hospital	hospital	NN
cord-009417-458rrhcm	200	38	course	course	NN
cord-009417-458rrhcm	200	39	;	;	:
cord-009417-458rrhcm	200	40	and	and	CC
cord-009417-458rrhcm	200	41	the	the	DT
cord-009417-458rrhcm	200	42	potential	potential	JJ
cord-009417-458rrhcm	200	43	delay	delay	NN
cord-009417-458rrhcm	200	44	or	or	CC
cord-009417-458rrhcm	200	45	prevention	prevention	NN
cord-009417-458rrhcm	200	46	of	of	IN
cord-009417-458rrhcm	200	47	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	200	48	to	to	IN
cord-009417-458rrhcm	200	49	HLA	HLA	NNP
cord-009417-458rrhcm	200	50	and	and	CC
cord-009417-458rrhcm	200	51	platelet	platelet	NN
cord-009417-458rrhcm	200	52	antigens	antigen	NNS
cord-009417-458rrhcm	200	53	.	.	.
cord-009417-458rrhcm	201	1	45	45	CD
cord-009417-458rrhcm	202	1	The	the	DT
cord-009417-458rrhcm	202	2	development	development	NN
cord-009417-458rrhcm	202	3	of	of	IN
cord-009417-458rrhcm	202	4	refractoriness	refractoriness	NN
cord-009417-458rrhcm	202	5	to	to	IN
cord-009417-458rrhcm	202	6	platelet	platelet	NN
cord-009417-458rrhcm	202	7	transfusions	transfusion	NNS
cord-009417-458rrhcm	202	8	is	be	VBZ
cord-009417-458rrhcm	202	9	a	a	DT
cord-009417-458rrhcm	202	10	serious	serious	JJ
cord-009417-458rrhcm	202	11	event	event	NN
cord-009417-458rrhcm	202	12	heralded	herald	VBN
cord-009417-458rrhcm	202	13	by	by	IN
cord-009417-458rrhcm	202	14	a	a	DT
cord-009417-458rrhcm	202	15	falling	fall	VBG
cord-009417-458rrhcm	202	16	CCI	CCI	NNP
cord-009417-458rrhcm	202	17	.	.	.
cord-009417-458rrhcm	203	1	Poor	poor	JJ
cord-009417-458rrhcm	203	2	response	response	NN
cord-009417-458rrhcm	203	3	to	to	IN
cord-009417-458rrhcm	203	4	platelet	platelet	NN
cord-009417-458rrhcm	203	5	transfusions	transfusion	NNS
cord-009417-458rrhcm	203	6	can	can	MD
cord-009417-458rrhcm	203	7	be	be	VB
cord-009417-458rrhcm	203	8	seen	see	VBN
cord-009417-458rrhcm	203	9	in	in	IN
cord-009417-458rrhcm	203	10	patients	patient	NNS
cord-009417-458rrhcm	203	11	with	with	IN
cord-009417-458rrhcm	203	12	other	other	JJ
cord-009417-458rrhcm	203	13	reasons	reason	NNS
cord-009417-458rrhcm	203	14	for	for	IN
cord-009417-458rrhcm	203	15	platelet	platelet	NN
cord-009417-458rrhcm	203	16	consumption	consumption	NN
cord-009417-458rrhcm	203	17	,	,	,
cord-009417-458rrhcm	203	18	including	include	VBG
cord-009417-458rrhcm	203	19	splenomegaly	splenomegaly	NN
cord-009417-458rrhcm	203	20	,	,	,
cord-009417-458rrhcm	203	21	fever	fever	NN
cord-009417-458rrhcm	203	22	,	,	,
cord-009417-458rrhcm	203	23	trauma	trauma	NN
cord-009417-458rrhcm	203	24	and	and	CC
cord-009417-458rrhcm	203	25	crush	crush	NN
cord-009417-458rrhcm	203	26	injury	injury	NN
cord-009417-458rrhcm	203	27	,	,	,
cord-009417-458rrhcm	203	28	burns	burn	NNS
cord-009417-458rrhcm	203	29	,	,	,
cord-009417-458rrhcm	203	30	disseminated	disseminate	VBD
cord-009417-458rrhcm	203	31	intravascular	intravascular	JJ
cord-009417-458rrhcm	203	32	coagulation	coagulation	NN
cord-009417-458rrhcm	203	33	(	(	-LRB-
cord-009417-458rrhcm	203	34	DIC	DIC	NNP
cord-009417-458rrhcm	203	35	)	)	-RRB-
cord-009417-458rrhcm	203	36	,	,	,
cord-009417-458rrhcm	203	37	concomitant	concomitant	JJ
cord-009417-458rrhcm	203	38	drugs	drug	NNS
cord-009417-458rrhcm	203	39	,	,	,
cord-009417-458rrhcm	203	40	or	or	CC
cord-009417-458rrhcm	203	41	transfusion	transfusion	NN
cord-009417-458rrhcm	203	42	of	of	IN
cord-009417-458rrhcm	203	43	platelets	platelet	NNS
cord-009417-458rrhcm	203	44	of	of	IN
cord-009417-458rrhcm	203	45	substandard	substandard	JJ
cord-009417-458rrhcm	203	46	quality	quality	NN
cord-009417-458rrhcm	203	47	.	.	.
cord-009417-458rrhcm	204	1	46	46	CD
cord-009417-458rrhcm	205	1	These	these	DT
cord-009417-458rrhcm	205	2	factors	factor	NNS
cord-009417-458rrhcm	205	3	should	should	MD
cord-009417-458rrhcm	205	4	be	be	VB
cord-009417-458rrhcm	205	5	sought	seek	VBN
cord-009417-458rrhcm	205	6	and	and	CC
cord-009417-458rrhcm	205	7	corrected	correct	VBN
cord-009417-458rrhcm	205	8	if	if	IN
cord-009417-458rrhcm	205	9	possible	possible	JJ
cord-009417-458rrhcm	205	10	.	.	.
cord-009417-458rrhcm	206	1	Alloimmunization	Alloimmunization	NNP
cord-009417-458rrhcm	206	2	is	be	VBZ
cord-009417-458rrhcm	206	3	characterized	characterize	VBN
cord-009417-458rrhcm	206	4	by	by	IN
cord-009417-458rrhcm	206	5	the	the	DT
cord-009417-458rrhcm	206	6	development	development	NN
cord-009417-458rrhcm	206	7	of	of	IN
cord-009417-458rrhcm	206	8	anti	anti	JJ
cord-009417-458rrhcm	206	9	-	-	JJ
cord-009417-458rrhcm	206	10	HLA	HLA	NNP
cord-009417-458rrhcm	206	11	or	or	CC
cord-009417-458rrhcm	206	12	platelet	platelet	NN
cord-009417-458rrhcm	206	13	-	-	HYPH
cord-009417-458rrhcm	206	14	specifi	specifi	NN
cord-009417-458rrhcm	206	15	c	c	NN
cord-009417-458rrhcm	206	16	antibodies	antibody	NNS
cord-009417-458rrhcm	206	17	,	,	,
cord-009417-458rrhcm	206	18	with	with	IN
cord-009417-458rrhcm	206	19	resultant	resultant	JJ
cord-009417-458rrhcm	206	20	immune	immune	JJ
cord-009417-458rrhcm	206	21	platelet	platelet	NN
cord-009417-458rrhcm	206	22	destruction	destruction	NN
cord-009417-458rrhcm	206	23	.	.	.
cord-009417-458rrhcm	207	1	As	as	RB
cord-009417-458rrhcm	207	2	many	many	JJ
cord-009417-458rrhcm	207	3	as	as	IN
cord-009417-458rrhcm	207	4	70	70	CD
cord-009417-458rrhcm	207	5	%	%	NN
cord-009417-458rrhcm	207	6	of	of	IN
cord-009417-458rrhcm	207	7	patients	patient	NNS
cord-009417-458rrhcm	207	8	receiving	receive	VBG
cord-009417-458rrhcm	207	9	multiple	multiple	JJ
cord-009417-458rrhcm	207	10	red	red	JJ
cord-009417-458rrhcm	207	11	cell	cell	NN
cord-009417-458rrhcm	207	12	or	or	CC
cord-009417-458rrhcm	207	13	platelet	platelet	NN
cord-009417-458rrhcm	207	14	transfusions	transfusion	NNS
cord-009417-458rrhcm	207	15	become	become	VBP
cord-009417-458rrhcm	207	16	immunized	immunize	VBN
cord-009417-458rrhcm	207	17	.	.	.
cord-009417-458rrhcm	208	1	45	45	CD
cord-009417-458rrhcm	208	2	Leukocyte	Leukocyte	NNP
cord-009417-458rrhcm	208	3	depletion	depletion	NN
cord-009417-458rrhcm	208	4	of	of	IN
cord-009417-458rrhcm	208	5	transfused	transfuse	VBN
cord-009417-458rrhcm	208	6	components	component	NNS
cord-009417-458rrhcm	208	7	can	can	MD
cord-009417-458rrhcm	208	8	prevent	prevent	VB
cord-009417-458rrhcm	208	9	or	or	CC
cord-009417-458rrhcm	208	10	delay	delay	VB
cord-009417-458rrhcm	208	11	this	this	DT
cord-009417-458rrhcm	208	12	phenomenon	phenomenon	NN
cord-009417-458rrhcm	208	13	,	,	,
cord-009417-458rrhcm	208	14	but	but	CC
cord-009417-458rrhcm	208	15	it	-PRON-	PRP
cord-009417-458rrhcm	208	16	is	be	VBZ
cord-009417-458rrhcm	208	17	important	important	JJ
cord-009417-458rrhcm	208	18	to	to	TO
cord-009417-458rrhcm	208	19	use	use	VB
cord-009417-458rrhcm	208	20	leukoreduced	leukoreduce	VBN
cord-009417-458rrhcm	208	21	components	component	NNS
cord-009417-458rrhcm	208	22	early	early	RB
cord-009417-458rrhcm	208	23	in	in	IN
cord-009417-458rrhcm	208	24	the	the	DT
cord-009417-458rrhcm	208	25	course	course	NN
cord-009417-458rrhcm	208	26	of	of	IN
cord-009417-458rrhcm	208	27	transfusion	transfusion	NN
cord-009417-458rrhcm	208	28	therapy	therapy	NN
cord-009417-458rrhcm	208	29	.	.	.
cord-009417-458rrhcm	209	1	45	45	CD
cord-009417-458rrhcm	209	2	,	,	,
cord-009417-458rrhcm	209	3	47	47	CD
cord-009417-458rrhcm	210	1	When	when	WRB
cord-009417-458rrhcm	210	2	patients	patient	NNS
cord-009417-458rrhcm	210	3	fail	fail	VBP
cord-009417-458rrhcm	210	4	to	to	TO
cord-009417-458rrhcm	210	5	achieve	achieve	VB
cord-009417-458rrhcm	210	6	expected	expect	VBN
cord-009417-458rrhcm	210	7	increments	increment	NNS
cord-009417-458rrhcm	210	8	after	after	IN
cord-009417-458rrhcm	210	9	platelet	platelet	NN
cord-009417-458rrhcm	210	10	transfusion	transfusion	NN
cord-009417-458rrhcm	210	11	,	,	,
cord-009417-458rrhcm	210	12	provision	provision	NN
cord-009417-458rrhcm	210	13	of	of	IN
cord-009417-458rrhcm	210	14	ABO	ABO	NNP
cord-009417-458rrhcm	210	15	-	-	HYPH
cord-009417-458rrhcm	210	16	specifi	specifi	NNP
cord-009417-458rrhcm	210	17	c	c	NN
cord-009417-458rrhcm	210	18	platelet	platelet	NN
cord-009417-458rrhcm	210	19	concentrates	concentrate	VBZ
cord-009417-458rrhcm	210	20	that	that	WDT
cord-009417-458rrhcm	210	21	are	be	VBP
cord-009417-458rrhcm	210	22	less	less	JJR
cord-009417-458rrhcm	210	23	than	than	IN
cord-009417-458rrhcm	210	24	48	48	CD
cord-009417-458rrhcm	210	25	hours	hour	NNS
cord-009417-458rrhcm	210	26	old	old	JJ
cord-009417-458rrhcm	210	27	may	may	MD
cord-009417-458rrhcm	210	28	improve	improve	VB
cord-009417-458rrhcm	210	29	the	the	DT
cord-009417-458rrhcm	210	30	response	response	NN
cord-009417-458rrhcm	210	31	.	.	.
cord-009417-458rrhcm	211	1	If	if	IN
cord-009417-458rrhcm	211	2	no	no	DT
cord-009417-458rrhcm	211	3	improvement	improvement	NN
cord-009417-458rrhcm	211	4	is	be	VBZ
cord-009417-458rrhcm	211	5	seen	see	VBN
cord-009417-458rrhcm	211	6	and	and	CC
cord-009417-458rrhcm	211	7	the	the	DT
cord-009417-458rrhcm	211	8	aforementioned	aforementioned	JJ
cord-009417-458rrhcm	211	9	medical	medical	JJ
cord-009417-458rrhcm	211	10	conditions	condition	NNS
cord-009417-458rrhcm	211	11	are	be	VBP
cord-009417-458rrhcm	211	12	excluded	exclude	VBN
cord-009417-458rrhcm	211	13	,	,	,
cord-009417-458rrhcm	211	14	the	the	DT
cord-009417-458rrhcm	211	15	patient	patient	NN
cord-009417-458rrhcm	211	16	should	should	MD
cord-009417-458rrhcm	211	17	be	be	VB
cord-009417-458rrhcm	211	18	screened	screen	VBN
cord-009417-458rrhcm	211	19	for	for	IN
cord-009417-458rrhcm	211	20	HLA	HLA	NNP
cord-009417-458rrhcm	211	21	antibodies	antibody	NNS
cord-009417-458rrhcm	211	22	or	or	CC
cord-009417-458rrhcm	211	23	be	be	VB
cord-009417-458rrhcm	211	24	HLA	HLA	NNP
cord-009417-458rrhcm	211	25	typed	type	VBN
cord-009417-458rrhcm	211	26	and	and	CC
cord-009417-458rrhcm	211	27	provided	provide	VBN
cord-009417-458rrhcm	211	28	with	with	IN
cord-009417-458rrhcm	211	29	HLA	HLA	NNP
cord-009417-458rrhcm	211	30	-	-	HYPH
cord-009417-458rrhcm	211	31	compatible	compatible	JJ
cord-009417-458rrhcm	211	32	single	single	JJ
cord-009417-458rrhcm	211	33	-	-	HYPH
cord-009417-458rrhcm	211	34	donor	donor	NN
cord-009417-458rrhcm	211	35	platelets	platelet	NNS
cord-009417-458rrhcm	211	36	.	.	.
cord-009417-458rrhcm	212	1	Alternatively	alternatively	RB
cord-009417-458rrhcm	212	2	,	,	,
cord-009417-458rrhcm	212	3	platelet	platelet	NN
cord-009417-458rrhcm	212	4	crossmatching	crossmatche	VBG
cord-009417-458rrhcm	212	5	with	with	IN
cord-009417-458rrhcm	212	6	the	the	DT
cord-009417-458rrhcm	212	7	patient	patient	NN
cord-009417-458rrhcm	212	8	's	's	POS
cord-009417-458rrhcm	212	9	serum	serum	NN
cord-009417-458rrhcm	212	10	can	can	MD
cord-009417-458rrhcm	212	11	be	be	VB
cord-009417-458rrhcm	212	12	carried	carry	VBN
cord-009417-458rrhcm	212	13	out	out	RP
cord-009417-458rrhcm	212	14	.	.	.
cord-009417-458rrhcm	213	1	There	there	EX
cord-009417-458rrhcm	213	2	is	be	VBZ
cord-009417-458rrhcm	213	3	no	no	DT
cord-009417-458rrhcm	213	4	advantage	advantage	NN
cord-009417-458rrhcm	213	5	to	to	IN
cord-009417-458rrhcm	213	6	unmatched	unmatched	JJ
cord-009417-458rrhcm	213	7	singledonor	singledonor	NN
cord-009417-458rrhcm	213	8	platelets	platelet	NNS
cord-009417-458rrhcm	213	9	in	in	IN
cord-009417-458rrhcm	213	10	this	this	DT
cord-009417-458rrhcm	213	11	situation	situation	NN
cord-009417-458rrhcm	213	12	.	.	.
cord-009417-458rrhcm	214	1	Standard	standard	JJ
cord-009417-458rrhcm	214	2	FFP	FFP	NNP
cord-009417-458rrhcm	214	3	is	be	VBZ
cord-009417-458rrhcm	214	4	prepared	prepare	VBN
cord-009417-458rrhcm	214	5	by	by	IN
cord-009417-458rrhcm	214	6	centrifugation	centrifugation	NN
cord-009417-458rrhcm	214	7	of	of	IN
cord-009417-458rrhcm	214	8	WB	WB	NNP
cord-009417-458rrhcm	214	9	and	and	CC
cord-009417-458rrhcm	214	10	is	be	VBZ
cord-009417-458rrhcm	214	11	frozen	freeze	VBN
cord-009417-458rrhcm	214	12	within	within	IN
cord-009417-458rrhcm	214	13	8	8	CD
cord-009417-458rrhcm	214	14	hours	hour	NNS
cord-009417-458rrhcm	214	15	of	of	IN
cord-009417-458rrhcm	214	16	blood	blood	NN
cord-009417-458rrhcm	214	17	donation	donation	NN
cord-009417-458rrhcm	214	18	.	.	.
cord-009417-458rrhcm	215	1	1,2	1,2	CD
cord-009417-458rrhcm	215	2	FFP	FFP	NNP
cord-009417-458rrhcm	215	3	may	may	MD
cord-009417-458rrhcm	215	4	be	be	VB
cord-009417-458rrhcm	215	5	stored	store	VBN
cord-009417-458rrhcm	215	6	frozen	frozen	JJ
cord-009417-458rrhcm	215	7	for	for	IN
cord-009417-458rrhcm	215	8	1	1	CD
cord-009417-458rrhcm	215	9	year	year	NN
cord-009417-458rrhcm	215	10	.	.	.
cord-009417-458rrhcm	216	1	The	the	DT
cord-009417-458rrhcm	216	2	usual	usual	JJ
cord-009417-458rrhcm	216	3	volume	volume	NN
cord-009417-458rrhcm	216	4	is	be	VBZ
cord-009417-458rrhcm	216	5	about	about	RB
cord-009417-458rrhcm	216	6	250	250	CD
cord-009417-458rrhcm	216	7	mL	ml	NN
cord-009417-458rrhcm	216	8	,	,	,
cord-009417-458rrhcm	216	9	depending	depend	VBG
cord-009417-458rrhcm	216	10	on	on	IN
cord-009417-458rrhcm	216	11	the	the	DT
cord-009417-458rrhcm	216	12	donor	donor	NN
cord-009417-458rrhcm	216	13	's	's	POS
cord-009417-458rrhcm	216	14	Hct	Hct	NNP
cord-009417-458rrhcm	216	15	.	.	.
cord-009417-458rrhcm	217	1	The	the	DT
cord-009417-458rrhcm	217	2	most	most	RBS
cord-009417-458rrhcm	217	3	common	common	JJ
cord-009417-458rrhcm	217	4	method	method	NN
cord-009417-458rrhcm	217	5	of	of	IN
cord-009417-458rrhcm	217	6	thawing	thaw	VBG
cord-009417-458rrhcm	217	7	before	before	IN
cord-009417-458rrhcm	217	8	transfusion	transfusion	NN
cord-009417-458rrhcm	217	9	is	be	VBZ
cord-009417-458rrhcm	217	10	soaking	soak	VBG
cord-009417-458rrhcm	217	11	in	in	IN
cord-009417-458rrhcm	217	12	a	a	DT
cord-009417-458rrhcm	217	13	37	37	CD
cord-009417-458rrhcm	217	14	°	°	NN
cord-009417-458rrhcm	217	15	C	c	NN
cord-009417-458rrhcm	217	16	water	water	NN
cord-009417-458rrhcm	217	17	bath	bath	NN
cord-009417-458rrhcm	217	18	,	,	,
cord-009417-458rrhcm	217	19	which	which	WDT
cord-009417-458rrhcm	217	20	requires	require	VBZ
cord-009417-458rrhcm	217	21	about	about	RB
cord-009417-458rrhcm	217	22	30	30	CD
cord-009417-458rrhcm	217	23	to	to	TO
cord-009417-458rrhcm	217	24	45	45	CD
cord-009417-458rrhcm	217	25	minutes	minute	NNS
cord-009417-458rrhcm	217	26	.	.	.
cord-009417-458rrhcm	218	1	Once	once	RB
cord-009417-458rrhcm	218	2	thawed	thaw	VBN
cord-009417-458rrhcm	218	3	,	,	,
cord-009417-458rrhcm	218	4	FFP	FFP	NNP
cord-009417-458rrhcm	218	5	can	can	MD
cord-009417-458rrhcm	218	6	be	be	VB
cord-009417-458rrhcm	218	7	stored	store	VBN
cord-009417-458rrhcm	218	8	refrigerated	refrigerated	JJ
cord-009417-458rrhcm	218	9	for	for	IN
cord-009417-458rrhcm	218	10	a	a	DT
cord-009417-458rrhcm	218	11	maximum	maximum	NN
cord-009417-458rrhcm	218	12	of	of	IN
cord-009417-458rrhcm	218	13	24	24	CD
cord-009417-458rrhcm	218	14	hours	hour	NNS
cord-009417-458rrhcm	218	15	.	.	.
cord-009417-458rrhcm	219	1	When	when	WRB
cord-009417-458rrhcm	219	2	prepared	prepare	VBN
cord-009417-458rrhcm	219	3	and	and	CC
cord-009417-458rrhcm	219	4	stored	store	VBN
cord-009417-458rrhcm	219	5	in	in	IN
cord-009417-458rrhcm	219	6	this	this	DT
cord-009417-458rrhcm	219	7	manner	manner	NN
cord-009417-458rrhcm	219	8	,	,	,
cord-009417-458rrhcm	219	9	FFP	FFP	NNP
cord-009417-458rrhcm	219	10	supplies	supply	VBZ
cord-009417-458rrhcm	219	11	all	all	PDT
cord-009417-458rrhcm	219	12	the	the	DT
cord-009417-458rrhcm	219	13	constituents	constituent	NNS
cord-009417-458rrhcm	219	14	in	in	IN
cord-009417-458rrhcm	219	15	the	the	DT
cord-009417-458rrhcm	219	16	amounts	amount	NNS
cord-009417-458rrhcm	219	17	normally	normally	RB
cord-009417-458rrhcm	219	18	present	present	JJ
cord-009417-458rrhcm	219	19	in	in	IN
cord-009417-458rrhcm	219	20	circulating	circulate	VBG
cord-009417-458rrhcm	219	21	plasma	plasma	NN
cord-009417-458rrhcm	219	22	,	,	,
cord-009417-458rrhcm	219	23	including	include	VBG
cord-009417-458rrhcm	219	24	stable	stable	JJ
cord-009417-458rrhcm	219	25	and	and	CC
cord-009417-458rrhcm	219	26	labile	labile	JJ
cord-009417-458rrhcm	219	27	coagulation	coagulation	NN
cord-009417-458rrhcm	219	28	factors	factor	NNS
cord-009417-458rrhcm	219	29	,	,	,
cord-009417-458rrhcm	219	30	complement	complement	NN
cord-009417-458rrhcm	219	31	,	,	,
cord-009417-458rrhcm	219	32	albumin	albumin	NN
cord-009417-458rrhcm	219	33	,	,	,
cord-009417-458rrhcm	219	34	and	and	CC
cord-009417-458rrhcm	219	35	globulins	globulin	NNS
cord-009417-458rrhcm	219	36	.	.	.
cord-009417-458rrhcm	220	1	By	by	IN
cord-009417-458rrhcm	220	2	convention	convention	NN
cord-009417-458rrhcm	220	3	,	,	,
cord-009417-458rrhcm	220	4	the	the	DT
cord-009417-458rrhcm	220	5	coagulation	coagulation	NN
cord-009417-458rrhcm	220	6	factors	factor	NNS
cord-009417-458rrhcm	220	7	are	be	VBP
cord-009417-458rrhcm	220	8	present	present	JJ
cord-009417-458rrhcm	220	9	in	in	IN
cord-009417-458rrhcm	220	10	concentrations	concentration	NNS
cord-009417-458rrhcm	220	11	of	of	IN
cord-009417-458rrhcm	220	12	1	1	CD
cord-009417-458rrhcm	220	13	U	U	NNP
cord-009417-458rrhcm	220	14	/	/	SYM
cord-009417-458rrhcm	220	15	mL.	mL.	NNP
cord-009417-458rrhcm	220	16	Crossmatching	Crossmatching	NNP
cord-009417-458rrhcm	220	17	to	to	IN
cord-009417-458rrhcm	220	18	the	the	DT
cord-009417-458rrhcm	220	19	recipient	recipient	NN
cord-009417-458rrhcm	220	20	is	be	VBZ
cord-009417-458rrhcm	220	21	not	not	RB
cord-009417-458rrhcm	220	22	performed	perform	VBN
cord-009417-458rrhcm	220	23	,	,	,
cord-009417-458rrhcm	220	24	but	but	CC
cord-009417-458rrhcm	220	25	FFP	FFP	NNP
cord-009417-458rrhcm	220	26	must	must	MD
cord-009417-458rrhcm	220	27	be	be	VB
cord-009417-458rrhcm	220	28	ABO	ABO	NNP
cord-009417-458rrhcm	220	29	compatible	compatible	JJ
cord-009417-458rrhcm	220	30	.	.	.
cord-009417-458rrhcm	221	1	Standard	standard	JJ
cord-009417-458rrhcm	221	2	FFP	FFP	NNP
cord-009417-458rrhcm	221	3	is	be	VBZ
cord-009417-458rrhcm	221	4	as	as	RB
cord-009417-458rrhcm	221	5	likely	likely	JJ
cord-009417-458rrhcm	221	6	to	to	TO
cord-009417-458rrhcm	221	7	transmit	transmit	VB
cord-009417-458rrhcm	221	8	hepatitis	hepatitis	NN
cord-009417-458rrhcm	221	9	,	,	,
cord-009417-458rrhcm	221	10	HIV	HIV	NNP
cord-009417-458rrhcm	221	11	,	,	,
cord-009417-458rrhcm	221	12	and	and	CC
cord-009417-458rrhcm	221	13	most	most	JJS
cord-009417-458rrhcm	221	14	other	other	JJ
cord-009417-458rrhcm	221	15	transfusion	transfusion	NN
cord-009417-458rrhcm	221	16	-	-	HYPH
cord-009417-458rrhcm	221	17	related	relate	VBN
cord-009417-458rrhcm	221	18	infections	infection	NNS
cord-009417-458rrhcm	221	19	as	as	IN
cord-009417-458rrhcm	221	20	cellular	cellular	JJ
cord-009417-458rrhcm	221	21	components	component	NNS
cord-009417-458rrhcm	221	22	are	be	VBP
cord-009417-458rrhcm	221	23	.	.	.
cord-009417-458rrhcm	222	1	New	new	JJ
cord-009417-458rrhcm	222	2	FFP	FFP	NNP
cord-009417-458rrhcm	222	3	products	product	NNS
cord-009417-458rrhcm	222	4	have	have	VBP
cord-009417-458rrhcm	222	5	recently	recently	RB
cord-009417-458rrhcm	222	6	been	be	VBN
cord-009417-458rrhcm	222	7	introduced	introduce	VBN
cord-009417-458rrhcm	222	8	in	in	IN
cord-009417-458rrhcm	222	9	response	response	NN
cord-009417-458rrhcm	222	10	to	to	IN
cord-009417-458rrhcm	222	11	concern	concern	NN
cord-009417-458rrhcm	222	12	about	about	IN
cord-009417-458rrhcm	222	13	the	the	DT
cord-009417-458rrhcm	222	14	transmission	transmission	NN
cord-009417-458rrhcm	222	15	of	of	IN
cord-009417-458rrhcm	222	16	infectious	infectious	JJ
cord-009417-458rrhcm	222	17	diseases	disease	NNS
cord-009417-458rrhcm	222	18	.	.	.
cord-009417-458rrhcm	223	1	One	one	CD
cord-009417-458rrhcm	223	2	such	such	JJ
cord-009417-458rrhcm	223	3	product	product	NN
cord-009417-458rrhcm	223	4	is	be	VBZ
cord-009417-458rrhcm	223	5	solventdetergent	solventdetergent	JJ
cord-009417-458rrhcm	223	6	-	-	HYPH
cord-009417-458rrhcm	223	7	treated	treat	VBN
cord-009417-458rrhcm	223	8	FFP	ffp	NN
cord-009417-458rrhcm	223	9	.	.	.
cord-009417-458rrhcm	224	1	48	48	CD
cord-009417-458rrhcm	224	2	Solvent	solvent	NN
cord-009417-458rrhcm	224	3	-	-	HYPH
cord-009417-458rrhcm	224	4	detergent	detergent	NN
cord-009417-458rrhcm	224	5	treatment	treatment	NN
cord-009417-458rrhcm	224	6	is	be	VBZ
cord-009417-458rrhcm	224	7	a	a	DT
cord-009417-458rrhcm	224	8	means	means	NN
cord-009417-458rrhcm	224	9	of	of	IN
cord-009417-458rrhcm	224	10	viral	viral	JJ
cord-009417-458rrhcm	224	11	inactivation	inactivation	NN
cord-009417-458rrhcm	224	12	that	that	WDT
cord-009417-458rrhcm	224	13	removes	remove	VBZ
cord-009417-458rrhcm	224	14	the	the	DT
cord-009417-458rrhcm	224	15	infectivity	infectivity	NN
cord-009417-458rrhcm	224	16	of	of	IN
cord-009417-458rrhcm	224	17	lipid	lipid	NN
cord-009417-458rrhcm	224	18	-	-	HYPH
cord-009417-458rrhcm	224	19	enveloped	envelop	VBN
cord-009417-458rrhcm	224	20	viruses	virus	NNS
cord-009417-458rrhcm	224	21	,	,	,
cord-009417-458rrhcm	224	22	such	such	JJ
cord-009417-458rrhcm	224	23	as	as	IN
cord-009417-458rrhcm	224	24	hepatitis	hepatitis	NN
cord-009417-458rrhcm	224	25	B	B	NNP
cord-009417-458rrhcm	224	26	and	and	CC
cord-009417-458rrhcm	224	27	C	C	NNP
cord-009417-458rrhcm	224	28	and	and	CC
cord-009417-458rrhcm	224	29	HIV	HIV	NNP
cord-009417-458rrhcm	224	30	.	.	.
cord-009417-458rrhcm	225	1	Because	because	IN
cord-009417-458rrhcm	225	2	the	the	DT
cord-009417-458rrhcm	225	3	product	product	NN
cord-009417-458rrhcm	225	4	is	be	VBZ
cord-009417-458rrhcm	225	5	derived	derive	VBN
cord-009417-458rrhcm	225	6	from	from	IN
cord-009417-458rrhcm	225	7	pooled	pool	VBN
cord-009417-458rrhcm	225	8	plasma	plasma	NN
cord-009417-458rrhcm	225	9	,	,	,
cord-009417-458rrhcm	225	10	with	with	IN
cord-009417-458rrhcm	225	11	as	as	RB
cord-009417-458rrhcm	225	12	many	many	JJ
cord-009417-458rrhcm	225	13	as	as	IN
cord-009417-458rrhcm	225	14	2500	2500	CD
cord-009417-458rrhcm	225	15	donors	donor	NNS
cord-009417-458rrhcm	225	16	in	in	IN
cord-009417-458rrhcm	225	17	each	each	DT
cord-009417-458rrhcm	225	18	lot	lot	NN
cord-009417-458rrhcm	225	19	,	,	,
cord-009417-458rrhcm	225	20	it	-PRON-	PRP
cord-009417-458rrhcm	225	21	has	have	VBZ
cord-009417-458rrhcm	225	22	the	the	DT
cord-009417-458rrhcm	225	23	potential	potential	NN
cord-009417-458rrhcm	225	24	to	to	TO
cord-009417-458rrhcm	225	25	actually	actually	RB
cord-009417-458rrhcm	225	26	increase	increase	VB
cord-009417-458rrhcm	225	27	recipient	recipient	NN
cord-009417-458rrhcm	225	28	exposure	exposure	NN
cord-009417-458rrhcm	225	29	to	to	IN
cord-009417-458rrhcm	225	30	pathogens	pathogen	NNS
cord-009417-458rrhcm	225	31	not	not	RB
cord-009417-458rrhcm	225	32	inactivated	inactivate	VBN
cord-009417-458rrhcm	225	33	by	by	IN
cord-009417-458rrhcm	225	34	the	the	DT
cord-009417-458rrhcm	225	35	solvent	solvent	NN
cord-009417-458rrhcm	225	36	-	-	HYPH
cord-009417-458rrhcm	225	37	detergent	detergent	NN
cord-009417-458rrhcm	225	38	method	method	NN
cord-009417-458rrhcm	225	39	,	,	,
cord-009417-458rrhcm	225	40	such	such	JJ
cord-009417-458rrhcm	225	41	as	as	IN
cord-009417-458rrhcm	225	42	hepatitis	hepatitis	NNP
cord-009417-458rrhcm	225	43	A	A	NNP
cord-009417-458rrhcm	225	44	and	and	CC
cord-009417-458rrhcm	225	45	parvovirus	parvovirus	NN
cord-009417-458rrhcm	225	46	B19	B19	NNP
cord-009417-458rrhcm	225	47	,	,	,
cord-009417-458rrhcm	225	48	and	and	CC
cord-009417-458rrhcm	225	49	be	be	VB
cord-009417-458rrhcm	225	50	more	more	RBR
cord-009417-458rrhcm	225	51	vulnerable	vulnerable	JJ
cord-009417-458rrhcm	225	52	to	to	IN
cord-009417-458rrhcm	225	53	any	any	DT
cord-009417-458rrhcm	225	54	newly	newly	RB
cord-009417-458rrhcm	225	55	emerging	emerge	VBG
cord-009417-458rrhcm	225	56	non	non	JJ
cord-009417-458rrhcm	225	57	-	-	JJ
cord-009417-458rrhcm	225	58	lipid	lipid	JJ
cord-009417-458rrhcm	225	59	-	-	HYPH
cord-009417-458rrhcm	225	60	enveloped	envelop	VBN
cord-009417-458rrhcm	225	61	agent	agent	NN
cord-009417-458rrhcm	225	62	.	.	.
cord-009417-458rrhcm	226	1	A	a	DT
cord-009417-458rrhcm	226	2	variety	variety	NN
cord-009417-458rrhcm	226	3	of	of	IN
cord-009417-458rrhcm	226	4	other	other	JJ
cord-009417-458rrhcm	226	5	techniques	technique	NNS
cord-009417-458rrhcm	226	6	for	for	IN
cord-009417-458rrhcm	226	7	reducing	reduce	VBG
cord-009417-458rrhcm	226	8	pathogen	pathogen	NN
cord-009417-458rrhcm	226	9	exposure	exposure	NN
cord-009417-458rrhcm	226	10	in	in	IN
cord-009417-458rrhcm	226	11	FFP	FFP	NNP
cord-009417-458rrhcm	226	12	have	have	VBP
cord-009417-458rrhcm	226	13	been	be	VBN
cord-009417-458rrhcm	226	14	developed	develop	VBN
cord-009417-458rrhcm	226	15	,	,	,
cord-009417-458rrhcm	226	16	including	include	VBG
cord-009417-458rrhcm	226	17	exposure	exposure	NN
cord-009417-458rrhcm	226	18	to	to	IN
cord-009417-458rrhcm	226	19	low	low	JJ
cord-009417-458rrhcm	226	20	pH	ph	NN
cord-009417-458rrhcm	226	21	or	or	CC
cord-009417-458rrhcm	226	22	vapor	vapor	NN
cord-009417-458rrhcm	226	23	heating	heating	NN
cord-009417-458rrhcm	226	24	and	and	CC
cord-009417-458rrhcm	226	25	treatment	treatment	NN
cord-009417-458rrhcm	226	26	with	with	IN
cord-009417-458rrhcm	226	27	ultraviolet	ultraviolet	NN
cord-009417-458rrhcm	226	28	irradiation	irradiation	NN
cord-009417-458rrhcm	226	29	,	,	,
cord-009417-458rrhcm	226	30	gamma	gamma	NN
cord-009417-458rrhcm	226	31	irradiation	irradiation	NN
cord-009417-458rrhcm	226	32	,	,	,
cord-009417-458rrhcm	226	33	or	or	CC
cord-009417-458rrhcm	226	34	psoralens	psoralens	NNP
cord-009417-458rrhcm	226	35	and	and	CC
cord-009417-458rrhcm	226	36	light	light	NN
cord-009417-458rrhcm	226	37	to	to	TO
cord-009417-458rrhcm	226	38	inactivate	inactivate	VB
cord-009417-458rrhcm	226	39	pathogens	pathogen	NNS
cord-009417-458rrhcm	226	40	by	by	IN
cord-009417-458rrhcm	226	41	inducing	induce	VBG
cord-009417-458rrhcm	226	42	DNA	dna	NN
cord-009417-458rrhcm	226	43	damage	damage	NN
cord-009417-458rrhcm	226	44	.	.	.
cord-009417-458rrhcm	227	1	49	49	CD
cord-009417-458rrhcm	228	1	Because	because	IN
cord-009417-458rrhcm	228	2	none	none	NN
cord-009417-458rrhcm	228	3	of	of	IN
cord-009417-458rrhcm	228	4	the	the	DT
cord-009417-458rrhcm	228	5	FFP	FFP	NNP
cord-009417-458rrhcm	228	6	products	product	NNS
cord-009417-458rrhcm	228	7	is	be	VBZ
cord-009417-458rrhcm	228	8	entirely	entirely	RB
cord-009417-458rrhcm	228	9	free	free	JJ
cord-009417-458rrhcm	228	10	from	from	IN
cord-009417-458rrhcm	228	11	the	the	DT
cord-009417-458rrhcm	228	12	risk	risk	NN
cord-009417-458rrhcm	228	13	of	of	IN
cord-009417-458rrhcm	228	14	disease	disease	NN
cord-009417-458rrhcm	228	15	transmission	transmission	NN
cord-009417-458rrhcm	228	16	or	or	CC
cord-009417-458rrhcm	228	17	other	other	JJ
cord-009417-458rrhcm	228	18	adverse	adverse	JJ
cord-009417-458rrhcm	228	19	effects	effect	NNS
cord-009417-458rrhcm	228	20	and	and	CC
cord-009417-458rrhcm	228	21	because	because	IN
cord-009417-458rrhcm	228	22	infection	infection	NN
cord-009417-458rrhcm	228	23	-	-	HYPH
cord-009417-458rrhcm	228	24	reducing	reduce	VBG
cord-009417-458rrhcm	228	25	modifi	modifi	JJ
cord-009417-458rrhcm	228	26	cations	cation	NNS
cord-009417-458rrhcm	228	27	add	add	VBP
cord-009417-458rrhcm	228	28	significantly	significantly	RB
cord-009417-458rrhcm	228	29	to	to	IN
cord-009417-458rrhcm	228	30	the	the	DT
cord-009417-458rrhcm	228	31	cost	cost	NN
cord-009417-458rrhcm	228	32	of	of	IN
cord-009417-458rrhcm	228	33	the	the	DT
cord-009417-458rrhcm	228	34	components	component	NNS
cord-009417-458rrhcm	228	35	,	,	,
cord-009417-458rrhcm	228	36	FFP	FFP	NNP
cord-009417-458rrhcm	228	37	should	should	MD
cord-009417-458rrhcm	228	38	be	be	VB
cord-009417-458rrhcm	228	39	used	use	VBN
cord-009417-458rrhcm	228	40	judiciously	judiciously	RB
cord-009417-458rrhcm	228	41	.	.	.
cord-009417-458rrhcm	229	1	50	50	CD
cord-009417-458rrhcm	230	1	It	-PRON-	PRP
cord-009417-458rrhcm	230	2	should	should	MD
cord-009417-458rrhcm	230	3	be	be	VB
cord-009417-458rrhcm	230	4	administered	administer	VBN
cord-009417-458rrhcm	230	5	only	only	RB
cord-009417-458rrhcm	230	6	to	to	TO
cord-009417-458rrhcm	230	7	provide	provide	VB
cord-009417-458rrhcm	230	8	coagulation	coagulation	NN
cord-009417-458rrhcm	230	9	factors	factor	NNS
cord-009417-458rrhcm	230	10	or	or	CC
cord-009417-458rrhcm	230	11	plasma	plasma	NN
cord-009417-458rrhcm	230	12	proteins	protein	NNS
cord-009417-458rrhcm	230	13	that	that	WDT
cord-009417-458rrhcm	230	14	can	can	MD
cord-009417-458rrhcm	230	15	not	not	RB
cord-009417-458rrhcm	230	16	be	be	VB
cord-009417-458rrhcm	230	17	obtained	obtain	VBN
cord-009417-458rrhcm	230	18	from	from	IN
cord-009417-458rrhcm	230	19	safer	safe	JJR
cord-009417-458rrhcm	230	20	sources	source	NNS
cord-009417-458rrhcm	230	21	.	.	.
cord-009417-458rrhcm	231	1	FFP	FFP	NNP
cord-009417-458rrhcm	231	2	is	be	VBZ
cord-009417-458rrhcm	231	3	commonly	commonly	RB
cord-009417-458rrhcm	231	4	used	use	VBN
cord-009417-458rrhcm	231	5	to	to	TO
cord-009417-458rrhcm	231	6	treat	treat	VB
cord-009417-458rrhcm	231	7	bleeding	bleed	VBG
cord-009417-458rrhcm	231	8	patients	patient	NNS
cord-009417-458rrhcm	231	9	with	with	IN
cord-009417-458rrhcm	231	10	acquired	acquire	VBN
cord-009417-458rrhcm	231	11	defi	defi	NNP
cord-009417-458rrhcm	231	12	ciency	ciency	NNP
cord-009417-458rrhcm	231	13	of	of	IN
cord-009417-458rrhcm	231	14	multiple	multiple	JJ
cord-009417-458rrhcm	231	15	coagulation	coagulation	NN
cord-009417-458rrhcm	231	16	factors	factor	NNS
cord-009417-458rrhcm	231	17	,	,	,
cord-009417-458rrhcm	231	18	as	as	IN
cord-009417-458rrhcm	231	19	in	in	IN
cord-009417-458rrhcm	231	20	liver	liver	NN
cord-009417-458rrhcm	231	21	disease	disease	NN
cord-009417-458rrhcm	231	22	,	,	,
cord-009417-458rrhcm	231	23	DIC	DIC	NNP
cord-009417-458rrhcm	231	24	,	,	,
cord-009417-458rrhcm	231	25	or	or	CC
cord-009417-458rrhcm	231	26	dilutional	dilutional	JJ
cord-009417-458rrhcm	231	27	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	231	28	,	,	,
cord-009417-458rrhcm	231	29	or	or	CC
cord-009417-458rrhcm	231	30	to	to	TO
cord-009417-458rrhcm	231	31	treat	treat	VB
cord-009417-458rrhcm	231	32	patients	patient	NNS
cord-009417-458rrhcm	231	33	with	with	IN
cord-009417-458rrhcm	231	34	congenital	congenital	JJ
cord-009417-458rrhcm	231	35	defi	defi	NNP
cord-009417-458rrhcm	231	36	ciency	ciency	NN
cord-009417-458rrhcm	231	37	of	of	IN
cord-009417-458rrhcm	231	38	a	a	DT
cord-009417-458rrhcm	231	39	coagulation	coagulation	NN
cord-009417-458rrhcm	231	40	factor	factor	NN
cord-009417-458rrhcm	231	41	or	or	CC
cord-009417-458rrhcm	231	42	other	other	JJ
cord-009417-458rrhcm	231	43	protein	protein	NN
cord-009417-458rrhcm	231	44	for	for	IN
cord-009417-458rrhcm	231	45	which	which	WDT
cord-009417-458rrhcm	231	46	concentrates	concentrate	VBZ
cord-009417-458rrhcm	231	47	or	or	CC
cord-009417-458rrhcm	231	48	safer	safe	JJR
cord-009417-458rrhcm	231	49	sources	source	NNS
cord-009417-458rrhcm	231	50	do	do	VBP
cord-009417-458rrhcm	231	51	not	not	RB
cord-009417-458rrhcm	231	52	exist	exist	VB
cord-009417-458rrhcm	231	53	.	.	.
cord-009417-458rrhcm	232	1	FFP	FFP	NNP
cord-009417-458rrhcm	232	2	may	may	MD
cord-009417-458rrhcm	232	3	be	be	VB
cord-009417-458rrhcm	232	4	indicated	indicate	VBN
cord-009417-458rrhcm	232	5	for	for	IN
cord-009417-458rrhcm	232	6	emergency	emergency	NN
cord-009417-458rrhcm	232	7	reversal	reversal	NN
cord-009417-458rrhcm	232	8	of	of	IN
cord-009417-458rrhcm	232	9	the	the	DT
cord-009417-458rrhcm	232	10	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	232	11	induced	induce	VBN
cord-009417-458rrhcm	232	12	by	by	IN
cord-009417-458rrhcm	232	13	warfarin	warfarin	NN
cord-009417-458rrhcm	232	14	anticoagulants	anticoagulant	NNS
cord-009417-458rrhcm	232	15	when	when	WRB
cord-009417-458rrhcm	232	16	more	more	RBR
cord-009417-458rrhcm	232	17	concentrated	concentrated	JJ
cord-009417-458rrhcm	232	18	products	product	NNS
cord-009417-458rrhcm	232	19	are	be	VBP
cord-009417-458rrhcm	232	20	not	not	RB
cord-009417-458rrhcm	232	21	available	available	JJ
cord-009417-458rrhcm	232	22	or	or	CC
cord-009417-458rrhcm	232	23	for	for	IN
cord-009417-458rrhcm	232	24	the	the	DT
cord-009417-458rrhcm	232	25	provision	provision	NN
cord-009417-458rrhcm	232	26	of	of	IN
cord-009417-458rrhcm	232	27	protein	protein	NN
cord-009417-458rrhcm	232	28	C	C	NNP
cord-009417-458rrhcm	232	29	or	or	CC
cord-009417-458rrhcm	232	30	S	S	NNP
cord-009417-458rrhcm	232	31	in	in	IN
cord-009417-458rrhcm	232	32	patients	patient	NNS
cord-009417-458rrhcm	232	33	who	who	WP
cord-009417-458rrhcm	232	34	are	be	VBP
cord-009417-458rrhcm	232	35	defi	defi	NNP
cord-009417-458rrhcm	232	36	cient	cient	NNP
cord-009417-458rrhcm	232	37	and	and	CC
cord-009417-458rrhcm	232	38	suffering	suffer	VBG
cord-009417-458rrhcm	232	39	acute	acute	JJ
cord-009417-458rrhcm	232	40	thrombosis	thrombosis	NN
cord-009417-458rrhcm	232	41	.	.	.
cord-009417-458rrhcm	233	1	FFP	FFP	NNP
cord-009417-458rrhcm	233	2	should	should	MD
cord-009417-458rrhcm	233	3	be	be	VB
cord-009417-458rrhcm	233	4	administered	administer	VBN
cord-009417-458rrhcm	233	5	as	as	IN
cord-009417-458rrhcm	233	6	boluses	bolus	NNS
cord-009417-458rrhcm	233	7	as	as	RB
cord-009417-458rrhcm	233	8	rapidly	rapidly	RB
cord-009417-458rrhcm	233	9	as	as	RB
cord-009417-458rrhcm	233	10	feasible	feasible	JJ
cord-009417-458rrhcm	233	11	so	so	IN
cord-009417-458rrhcm	233	12	that	that	IN
cord-009417-458rrhcm	233	13	the	the	DT
cord-009417-458rrhcm	233	14	resulting	result	VBG
cord-009417-458rrhcm	233	15	factor	factor	NN
cord-009417-458rrhcm	233	16	levels	level	NNS
cord-009417-458rrhcm	233	17	allow	allow	VBP
cord-009417-458rrhcm	233	18	hemostasis	hemostasis	NN
cord-009417-458rrhcm	233	19	.	.	.
cord-009417-458rrhcm	234	1	The	the	DT
cord-009417-458rrhcm	234	2	use	use	NN
cord-009417-458rrhcm	234	3	of	of	IN
cord-009417-458rrhcm	234	4	FFP	FFP	NNP
cord-009417-458rrhcm	234	5	infusions	infusion	NNS
cord-009417-458rrhcm	234	6	without	without	IN
cord-009417-458rrhcm	234	7	adequate	adequate	JJ
cord-009417-458rrhcm	234	8	bolus	bolus	NN
cord-009417-458rrhcm	234	9	administration	administration	NN
cord-009417-458rrhcm	234	10	is	be	VBZ
cord-009417-458rrhcm	234	11	not	not	RB
cord-009417-458rrhcm	234	12	helpful	helpful	JJ
cord-009417-458rrhcm	234	13	.	.	.
cord-009417-458rrhcm	235	1	FFP	FFP	NNP
cord-009417-458rrhcm	235	2	should	should	MD
cord-009417-458rrhcm	235	3	not	not	RB
cord-009417-458rrhcm	235	4	be	be	VB
cord-009417-458rrhcm	235	5	used	use	VBN
cord-009417-458rrhcm	235	6	for	for	IN
cord-009417-458rrhcm	235	7	volume	volume	NN
cord-009417-458rrhcm	235	8	expansion	expansion	NN
cord-009417-458rrhcm	235	9	or	or	CC
cord-009417-458rrhcm	235	10	wound	wind	VBN
cord-009417-458rrhcm	235	11	healing	healing	NN
cord-009417-458rrhcm	235	12	or	or	CC
cord-009417-458rrhcm	235	13	as	as	IN
cord-009417-458rrhcm	235	14	a	a	DT
cord-009417-458rrhcm	235	15	nutritional	nutritional	JJ
cord-009417-458rrhcm	235	16	source	source	NN
cord-009417-458rrhcm	235	17	of	of	IN
cord-009417-458rrhcm	235	18	protein	protein	NN
cord-009417-458rrhcm	235	19	.	.	.
cord-009417-458rrhcm	236	1	FFP	FFP	NNP
cord-009417-458rrhcm	236	2	does	do	VBZ
cord-009417-458rrhcm	236	3	not	not	RB
cord-009417-458rrhcm	236	4	reverse	reverse	VB
cord-009417-458rrhcm	236	5	anticoagulation	anticoagulation	NN
cord-009417-458rrhcm	236	6	induced	induce	VBN
cord-009417-458rrhcm	236	7	by	by	IN
cord-009417-458rrhcm	236	8	heparin	heparin	NN
cord-009417-458rrhcm	236	9	and	and	CC
cord-009417-458rrhcm	236	10	in	in	IN
cord-009417-458rrhcm	236	11	theory	theory	NN
cord-009417-458rrhcm	236	12	might	may	MD
cord-009417-458rrhcm	236	13	exacerbate	exacerbate	VB
cord-009417-458rrhcm	236	14	bleeding	bleed	VBG
cord-009417-458rrhcm	236	15	by	by	IN
cord-009417-458rrhcm	236	16	supplying	supply	VBG
cord-009417-458rrhcm	236	17	more	more	JJR
cord-009417-458rrhcm	236	18	antithrombin	antithrombin	NN
cord-009417-458rrhcm	236	19	,	,	,
cord-009417-458rrhcm	236	20	heparin	heparin	NNP
cord-009417-458rrhcm	236	21	's	's	POS
cord-009417-458rrhcm	236	22	cofactor	cofactor	NN
cord-009417-458rrhcm	236	23	.	.	.
cord-009417-458rrhcm	237	1	Prophylactic	prophylactic	JJ
cord-009417-458rrhcm	237	2	administration	administration	NN
cord-009417-458rrhcm	237	3	of	of	IN
cord-009417-458rrhcm	237	4	FFP	FFP	NNP
cord-009417-458rrhcm	237	5	does	do	VBZ
cord-009417-458rrhcm	237	6	not	not	RB
cord-009417-458rrhcm	237	7	improve	improve	VB
cord-009417-458rrhcm	237	8	patient	patient	JJ
cord-009417-458rrhcm	237	9	outcome	outcome	NN
cord-009417-458rrhcm	237	10	in	in	IN
cord-009417-458rrhcm	237	11	the	the	DT
cord-009417-458rrhcm	237	12	setting	setting	NN
cord-009417-458rrhcm	237	13	of	of	IN
cord-009417-458rrhcm	237	14	massive	massive	JJ
cord-009417-458rrhcm	237	15	transfusion	transfusion	NN
cord-009417-458rrhcm	237	16	or	or	CC
cord-009417-458rrhcm	237	17	cardiac	cardiac	JJ
cord-009417-458rrhcm	237	18	surgery	surgery	NN
cord-009417-458rrhcm	237	19	unless	unless	IN
cord-009417-458rrhcm	237	20	there	there	EX
cord-009417-458rrhcm	237	21	is	be	VBZ
cord-009417-458rrhcm	237	22	bleeding	bleed	VBG
cord-009417-458rrhcm	237	23	with	with	IN
cord-009417-458rrhcm	237	24	an	an	DT
cord-009417-458rrhcm	237	25	associated	associate	VBN
cord-009417-458rrhcm	237	26	documented	document	VBN
cord-009417-458rrhcm	237	27	coagulation	coagulation	NN
cord-009417-458rrhcm	237	28	abnormality	abnormality	NN
cord-009417-458rrhcm	237	29	.	.	.
cord-009417-458rrhcm	238	1	51	51	CD
cord-009417-458rrhcm	238	2	,	,	,
cord-009417-458rrhcm	238	3	52	52	CD
cord-009417-458rrhcm	238	4	Patients	patient	NNS
cord-009417-458rrhcm	238	5	do	do	VBP
cord-009417-458rrhcm	238	6	not	not	RB
cord-009417-458rrhcm	238	7	usually	usually	RB
cord-009417-458rrhcm	238	8	bleed	bleed	VB
cord-009417-458rrhcm	238	9	as	as	IN
cord-009417-458rrhcm	238	10	a	a	DT
cord-009417-458rrhcm	238	11	result	result	NN
cord-009417-458rrhcm	238	12	of	of	IN
cord-009417-458rrhcm	238	13	coagulation	coagulation	NN
cord-009417-458rrhcm	238	14	factor	factor	NN
cord-009417-458rrhcm	238	15	insuffi	insuffi	NNP
cord-009417-458rrhcm	238	16	ciency	ciency	NNP
cord-009417-458rrhcm	238	17	when	when	WRB
cord-009417-458rrhcm	238	18	the	the	DT
cord-009417-458rrhcm	238	19	international	international	JJ
cord-009417-458rrhcm	238	20	normalized	normalized	JJ
cord-009417-458rrhcm	238	21	ratio	ratio	NN
cord-009417-458rrhcm	238	22	(	(	-LRB-
cord-009417-458rrhcm	238	23	INR	INR	NNP
cord-009417-458rrhcm	238	24	)	)	-RRB-
cord-009417-458rrhcm	238	25	is	be	VBZ
cord-009417-458rrhcm	238	26	less	less	JJR
cord-009417-458rrhcm	238	27	than	than	IN
cord-009417-458rrhcm	238	28	about	about	IN
cord-009417-458rrhcm	238	29	2.0	2.0	CD
cord-009417-458rrhcm	238	30	,	,	,
cord-009417-458rrhcm	238	31	and	and	CC
cord-009417-458rrhcm	238	32	even	even	RB
cord-009417-458rrhcm	238	33	then	then	RB
cord-009417-458rrhcm	238	34	the	the	DT
cord-009417-458rrhcm	238	35	results	result	NNS
cord-009417-458rrhcm	238	36	are	be	VBP
cord-009417-458rrhcm	238	37	not	not	RB
cord-009417-458rrhcm	238	38	always	always	RB
cord-009417-458rrhcm	238	39	predictable	predictable	JJ
cord-009417-458rrhcm	238	40	.	.	.
cord-009417-458rrhcm	239	1	53	53	CD
cord-009417-458rrhcm	240	1	The	the	DT
cord-009417-458rrhcm	240	2	partial	partial	JJ
cord-009417-458rrhcm	240	3	thromboplastin	thromboplastin	NN
cord-009417-458rrhcm	240	4	time	time	NN
cord-009417-458rrhcm	240	5	(	(	-LRB-
cord-009417-458rrhcm	240	6	PTT	PTT	NNP
cord-009417-458rrhcm	240	7	)	)	-RRB-
cord-009417-458rrhcm	240	8	is	be	VBZ
cord-009417-458rrhcm	240	9	not	not	RB
cord-009417-458rrhcm	240	10	useful	useful	JJ
cord-009417-458rrhcm	240	11	in	in	IN
cord-009417-458rrhcm	240	12	predicting	predict	VBG
cord-009417-458rrhcm	240	13	procedural	procedural	JJ
cord-009417-458rrhcm	240	14	bleeding	bleed	VBG
cord-009417-458rrhcm	240	15	risk	risk	NN
cord-009417-458rrhcm	240	16	.	.	.
cord-009417-458rrhcm	241	1	54	54	CD
cord-009417-458rrhcm	241	2	FFP	FFP	NNP
cord-009417-458rrhcm	241	3	is	be	VBZ
cord-009417-458rrhcm	241	4	often	often	RB
cord-009417-458rrhcm	241	5	requested	request	VBN
cord-009417-458rrhcm	241	6	prophylactically	prophylactically	RB
cord-009417-458rrhcm	241	7	before	before	IN
cord-009417-458rrhcm	241	8	an	an	DT
cord-009417-458rrhcm	241	9	invasive	invasive	JJ
cord-009417-458rrhcm	241	10	procedure	procedure	NN
cord-009417-458rrhcm	241	11	when	when	WRB
cord-009417-458rrhcm	241	12	the	the	DT
cord-009417-458rrhcm	241	13	patient	patient	NN
cord-009417-458rrhcm	241	14	exhibits	exhibit	VBZ
cord-009417-458rrhcm	241	15	mild	mild	JJ
cord-009417-458rrhcm	241	16	prolongation	prolongation	NN
cord-009417-458rrhcm	241	17	in	in	IN
cord-009417-458rrhcm	241	18	coagulation	coagulation	NN
cord-009417-458rrhcm	241	19	studies	study	NNS
cord-009417-458rrhcm	241	20	.	.	.
cord-009417-458rrhcm	242	1	Most	Most	JJS
cord-009417-458rrhcm	242	2	of	of	IN
cord-009417-458rrhcm	242	3	these	these	DT
cord-009417-458rrhcm	242	4	procedures	procedure	NNS
cord-009417-458rrhcm	242	5	may	may	MD
cord-009417-458rrhcm	242	6	be	be	VB
cord-009417-458rrhcm	242	7	carried	carry	VBN
cord-009417-458rrhcm	242	8	out	out	RP
cord-009417-458rrhcm	242	9	safely	safely	RB
cord-009417-458rrhcm	242	10	without	without	IN
cord-009417-458rrhcm	242	11	transfusing	transfuse	VBG
cord-009417-458rrhcm	242	12	FFP	ffp	NN
cord-009417-458rrhcm	242	13	.	.	.
cord-009417-458rrhcm	243	1	53	53	CD
cord-009417-458rrhcm	243	2	,	,	,
cord-009417-458rrhcm	243	3	55	55	CD
cord-009417-458rrhcm	243	4	FFP	FFP	NNP
cord-009417-458rrhcm	243	5	is	be	VBZ
cord-009417-458rrhcm	243	6	probably	probably	RB
cord-009417-458rrhcm	243	7	the	the	DT
cord-009417-458rrhcm	243	8	most	most	RBS
cord-009417-458rrhcm	243	9	misused	misuse	VBN
cord-009417-458rrhcm	243	10	blood	blood	NN
cord-009417-458rrhcm	243	11	component	component	NN
cord-009417-458rrhcm	243	12	,	,	,
cord-009417-458rrhcm	243	13	as	as	IN
cord-009417-458rrhcm	243	14	illustrated	illustrate	VBN
cord-009417-458rrhcm	243	15	by	by	IN
cord-009417-458rrhcm	243	16	retrospective	retrospective	JJ
cord-009417-458rrhcm	243	17	surveys	survey	NNS
cord-009417-458rrhcm	243	18	.	.	.
cord-009417-458rrhcm	244	1	56	56	CD
cord-009417-458rrhcm	244	2	Coagulation	coagulation	NN
cord-009417-458rrhcm	244	3	factors	factor	NNS
cord-009417-458rrhcm	244	4	are	be	VBP
cord-009417-458rrhcm	244	5	normally	normally	RB
cord-009417-458rrhcm	244	6	present	present	JJ
cord-009417-458rrhcm	244	7	in	in	IN
cord-009417-458rrhcm	244	8	the	the	DT
cord-009417-458rrhcm	244	9	blood	blood	NN
cord-009417-458rrhcm	244	10	far	far	RB
cord-009417-458rrhcm	244	11	in	in	IN
cord-009417-458rrhcm	244	12	excess	excess	NN
cord-009417-458rrhcm	244	13	of	of	IN
cord-009417-458rrhcm	244	14	the	the	DT
cord-009417-458rrhcm	244	15	minimum	minimum	JJ
cord-009417-458rrhcm	244	16	levels	level	NNS
cord-009417-458rrhcm	244	17	required	require	VBN
cord-009417-458rrhcm	244	18	for	for	IN
cord-009417-458rrhcm	244	19	hemostasis	hemostasis	NN
cord-009417-458rrhcm	244	20	.	.	.
cord-009417-458rrhcm	245	1	As	as	RB
cord-009417-458rrhcm	245	2	little	little	JJ
cord-009417-458rrhcm	245	3	as	as	IN
cord-009417-458rrhcm	245	4	10	10	CD
cord-009417-458rrhcm	245	5	%	%	NN
cord-009417-458rrhcm	245	6	of	of	IN
cord-009417-458rrhcm	245	7	the	the	DT
cord-009417-458rrhcm	245	8	normal	normal	JJ
cord-009417-458rrhcm	245	9	plasma	plasma	NN
cord-009417-458rrhcm	245	10	concentration	concentration	NN
cord-009417-458rrhcm	245	11	of	of	IN
cord-009417-458rrhcm	245	12	several	several	JJ
cord-009417-458rrhcm	245	13	factors	factor	NNS
cord-009417-458rrhcm	245	14	will	will	MD
cord-009417-458rrhcm	245	15	effect	effect	VB
cord-009417-458rrhcm	245	16	hemostasis	hemostasis	NN
cord-009417-458rrhcm	245	17	.	.	.
cord-009417-458rrhcm	246	1	Conversely	conversely	RB
cord-009417-458rrhcm	246	2	,	,	,
cord-009417-458rrhcm	246	3	FFP	FFP	NNP
cord-009417-458rrhcm	246	4	treatment	treatment	NN
cord-009417-458rrhcm	246	5	of	of	IN
cord-009417-458rrhcm	246	6	acquired	acquire	VBN
cord-009417-458rrhcm	246	7	multiple	multiple	JJ
cord-009417-458rrhcm	246	8	defi	defi	NNP
cord-009417-458rrhcm	246	9	ciencies	ciencie	NNS
cord-009417-458rrhcm	246	10	,	,	,
cord-009417-458rrhcm	246	11	as	as	IN
cord-009417-458rrhcm	246	12	in	in	IN
cord-009417-458rrhcm	246	13	hepatic	hepatic	JJ
cord-009417-458rrhcm	246	14	failure	failure	NN
cord-009417-458rrhcm	246	15	,	,	,
cord-009417-458rrhcm	246	16	is	be	VBZ
cord-009417-458rrhcm	246	17	often	often	RB
cord-009417-458rrhcm	246	18	ineffective	ineffective	JJ
cord-009417-458rrhcm	246	19	because	because	IN
cord-009417-458rrhcm	246	20	many	many	JJ
cord-009417-458rrhcm	246	21	patients	patient	NNS
cord-009417-458rrhcm	246	22	can	can	MD
cord-009417-458rrhcm	246	23	not	not	RB
cord-009417-458rrhcm	246	24	tolerate	tolerate	VB
cord-009417-458rrhcm	246	25	the	the	DT
cord-009417-458rrhcm	246	26	infusion	infusion	NN
cord-009417-458rrhcm	246	27	volumes	volume	NNS
cord-009417-458rrhcm	246	28	required	require	VBN
cord-009417-458rrhcm	246	29	to	to	TO
cord-009417-458rrhcm	246	30	achieve	achieve	VB
cord-009417-458rrhcm	246	31	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	246	32	levels	level	NNS
cord-009417-458rrhcm	246	33	of	of	IN
cord-009417-458rrhcm	246	34	coagulation	coagulation	NN
cord-009417-458rrhcm	246	35	factors	factor	NNS
cord-009417-458rrhcm	246	36	,	,	,
cord-009417-458rrhcm	246	37	even	even	RB
cord-009417-458rrhcm	246	38	transiently	transiently	RB
cord-009417-458rrhcm	246	39	.	.	.
cord-009417-458rrhcm	247	1	57	57	CD
cord-009417-458rrhcm	248	1	The	the	DT
cord-009417-458rrhcm	248	2	plasma	plasma	NN
cord-009417-458rrhcm	248	3	half	half	JJ
cord-009417-458rrhcm	248	4	-	-	HYPH
cord-009417-458rrhcm	248	5	life	life	NN
cord-009417-458rrhcm	248	6	of	of	IN
cord-009417-458rrhcm	248	7	transfused	transfuse	VBN
cord-009417-458rrhcm	248	8	factor	factor	NN
cord-009417-458rrhcm	248	9	VII	VII	NNP
cord-009417-458rrhcm	248	10	is	be	VBZ
cord-009417-458rrhcm	248	11	only	only	RB
cord-009417-458rrhcm	248	12	2	2	CD
cord-009417-458rrhcm	248	13	to	to	TO
cord-009417-458rrhcm	248	14	6	6	CD
cord-009417-458rrhcm	248	15	hours	hour	NNS
cord-009417-458rrhcm	248	16	.	.	.
cord-009417-458rrhcm	249	1	It	-PRON-	PRP
cord-009417-458rrhcm	249	2	may	may	MD
cord-009417-458rrhcm	249	3	be	be	VB
cord-009417-458rrhcm	249	4	impossible	impossible	JJ
cord-009417-458rrhcm	249	5	to	to	TO
cord-009417-458rrhcm	249	6	administer	administer	VB
cord-009417-458rrhcm	249	7	suffi	suffi	NNP
cord-009417-458rrhcm	249	8	cient	cient	NNP
cord-009417-458rrhcm	249	9	FFP	FFP	NNP
cord-009417-458rrhcm	249	10	every	every	DT
cord-009417-458rrhcm	249	11	few	few	JJ
cord-009417-458rrhcm	249	12	hours	hour	NNS
cord-009417-458rrhcm	249	13	without	without	IN
cord-009417-458rrhcm	249	14	encountering	encounter	VBG
cord-009417-458rrhcm	249	15	intravascular	intravascular	JJ
cord-009417-458rrhcm	249	16	volume	volume	NN
cord-009417-458rrhcm	249	17	overload	overload	NN
cord-009417-458rrhcm	249	18	.	.	.
cord-009417-458rrhcm	250	1	Finally	finally	RB
cord-009417-458rrhcm	250	2	,	,	,
cord-009417-458rrhcm	250	3	in	in	IN
cord-009417-458rrhcm	250	4	some	some	DT
cord-009417-458rrhcm	250	5	instances	instance	NNS
cord-009417-458rrhcm	250	6	,	,	,
cord-009417-458rrhcm	250	7	transfusion	transfusion	NN
cord-009417-458rrhcm	250	8	of	of	IN
cord-009417-458rrhcm	250	9	seemingly	seemingly	RB
cord-009417-458rrhcm	250	10	adequate	adequate	JJ
cord-009417-458rrhcm	250	11	volumes	volume	NNS
cord-009417-458rrhcm	250	12	may	may	MD
cord-009417-458rrhcm	250	13	still	still	RB
cord-009417-458rrhcm	250	14	fail	fail	VB
cord-009417-458rrhcm	250	15	to	to	TO
cord-009417-458rrhcm	250	16	correct	correct	VB
cord-009417-458rrhcm	250	17	the	the	DT
cord-009417-458rrhcm	250	18	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	250	19	.	.	.
cord-009417-458rrhcm	251	1	58	58	CD
cord-009417-458rrhcm	252	1	Careful	careful	JJ
cord-009417-458rrhcm	252	2	documentation	documentation	NN
cord-009417-458rrhcm	252	3	of	of	IN
cord-009417-458rrhcm	252	4	both	both	CC
cord-009417-458rrhcm	252	5	the	the	DT
cord-009417-458rrhcm	252	6	need	need	NN
cord-009417-458rrhcm	252	7	for	for	IN
cord-009417-458rrhcm	252	8	FFP	FFP	NNP
cord-009417-458rrhcm	252	9	and	and	CC
cord-009417-458rrhcm	252	10	the	the	DT
cord-009417-458rrhcm	252	11	adequacy	adequacy	NN
cord-009417-458rrhcm	252	12	and	and	CC
cord-009417-458rrhcm	252	13	outcomes	outcome	NNS
cord-009417-458rrhcm	252	14	of	of	IN
cord-009417-458rrhcm	252	15	therapy	therapy	NN
cord-009417-458rrhcm	252	16	is	be	VBZ
cord-009417-458rrhcm	252	17	essential	essential	JJ
cord-009417-458rrhcm	252	18	.	.	.
cord-009417-458rrhcm	253	1	59	59	CD
cord-009417-458rrhcm	253	2	Cryoprecipitate	Cryoprecipitate	NNP
cord-009417-458rrhcm	253	3	is	be	VBZ
cord-009417-458rrhcm	253	4	manufactured	manufacture	VBN
cord-009417-458rrhcm	253	5	by	by	IN
cord-009417-458rrhcm	253	6	thawing	thaw	VBG
cord-009417-458rrhcm	253	7	and	and	CC
cord-009417-458rrhcm	253	8	centrifuging	centrifuge	VBG
cord-009417-458rrhcm	253	9	FFP	FFP	NNP
cord-009417-458rrhcm	253	10	below	below	IN
cord-009417-458rrhcm	253	11	6º	6º	CD
cord-009417-458rrhcm	253	12	C	C	NNP
cord-009417-458rrhcm	253	13	and	and	CC
cord-009417-458rrhcm	253	14	resuspending	resuspend	VBG
cord-009417-458rrhcm	253	15	the	the	DT
cord-009417-458rrhcm	253	16	precipitated	precipitate	VBN
cord-009417-458rrhcm	253	17	proteins	protein	NNS
cord-009417-458rrhcm	253	18	in	in	IN
cord-009417-458rrhcm	253	19	about	about	RB
cord-009417-458rrhcm	253	20	15	15	CD
cord-009417-458rrhcm	253	21	mL	ml	NN
cord-009417-458rrhcm	253	22	of	of	IN
cord-009417-458rrhcm	253	23	supernatant	supernatant	JJ
cord-009417-458rrhcm	253	24	plasma	plasma	NN
cord-009417-458rrhcm	253	25	.	.	.
cord-009417-458rrhcm	254	1	1,2	1,2	LS
cord-009417-458rrhcm	255	1	Each	each	DT
cord-009417-458rrhcm	255	2	bag	bag	NN
cord-009417-458rrhcm	255	3	is	be	VBZ
cord-009417-458rrhcm	255	4	a	a	DT
cord-009417-458rrhcm	255	5	concentrated	concentrated	JJ
cord-009417-458rrhcm	255	6	source	source	NN
cord-009417-458rrhcm	255	7	of	of	IN
cord-009417-458rrhcm	255	8	factor	factor	NN
cord-009417-458rrhcm	255	9	VIII	VIII	NNP
cord-009417-458rrhcm	255	10	(	(	-LRB-
cord-009417-458rrhcm	255	11	80	80	CD
cord-009417-458rrhcm	255	12	to	to	TO
cord-009417-458rrhcm	255	13	120	120	CD
cord-009417-458rrhcm	255	14	units	unit	NNS
cord-009417-458rrhcm	255	15	)	)	-RRB-
cord-009417-458rrhcm	255	16	,	,	,
cord-009417-458rrhcm	255	17	von	von	NNP
cord-009417-458rrhcm	255	18	Willebrand	Willebrand	NNP
cord-009417-458rrhcm	255	19	factor	factor	NN
cord-009417-458rrhcm	255	20	(	(	-LRB-
cord-009417-458rrhcm	255	21	vWF	vwf	NN
cord-009417-458rrhcm	255	22	)	)	-RRB-
cord-009417-458rrhcm	255	23	(	(	-LRB-
cord-009417-458rrhcm	255	24	50	50	CD
cord-009417-458rrhcm	255	25	%	%	NN
cord-009417-458rrhcm	255	26	of	of	IN
cord-009417-458rrhcm	255	27	original	original	JJ
cord-009417-458rrhcm	255	28	plasma	plasma	NN
cord-009417-458rrhcm	255	29	content	content	NN
cord-009417-458rrhcm	255	30	)	)	-RRB-
cord-009417-458rrhcm	255	31	,	,	,
cord-009417-458rrhcm	255	32	fi	fi	NNP
cord-009417-458rrhcm	255	33	brinogen	brinogen	NNP
cord-009417-458rrhcm	255	34	(	(	-LRB-
cord-009417-458rrhcm	255	35	250	250	CD
cord-009417-458rrhcm	255	36	mg	mg	NNP
cord-009417-458rrhcm	255	37	)	)	-RRB-
cord-009417-458rrhcm	255	38	,	,	,
cord-009417-458rrhcm	255	39	factor	factor	NN
cord-009417-458rrhcm	255	40	XIII	XIII	NNP
cord-009417-458rrhcm	255	41	(	(	-LRB-
cord-009417-458rrhcm	255	42	30	30	CD
cord-009417-458rrhcm	255	43	%	%	NN
cord-009417-458rrhcm	255	44	of	of	IN
cord-009417-458rrhcm	255	45	original	original	JJ
cord-009417-458rrhcm	255	46	plasma	plasma	NN
cord-009417-458rrhcm	255	47	content	content	NN
cord-009417-458rrhcm	255	48	)	)	-RRB-
cord-009417-458rrhcm	255	49	,	,	,
cord-009417-458rrhcm	255	50	and	and	CC
cord-009417-458rrhcm	255	51	fi	fi	NNP
cord-009417-458rrhcm	255	52	bronectin	bronectin	NNP
cord-009417-458rrhcm	255	53	.	.	.
cord-009417-458rrhcm	256	1	Cryoprecipitate	Cryoprecipitate	NNP
cord-009417-458rrhcm	256	2	offers	offer	VBZ
cord-009417-458rrhcm	256	3	the	the	DT
cord-009417-458rrhcm	256	4	advantage	advantage	NN
cord-009417-458rrhcm	256	5	of	of	IN
cord-009417-458rrhcm	256	6	transfusing	transfuse	VBG
cord-009417-458rrhcm	256	7	more	more	JJR
cord-009417-458rrhcm	256	8	specifi	specifi	NN
cord-009417-458rrhcm	256	9	c	c	NN
cord-009417-458rrhcm	256	10	protein	protein	NN
cord-009417-458rrhcm	256	11	and	and	CC
cord-009417-458rrhcm	256	12	less	less	JJR
cord-009417-458rrhcm	256	13	total	total	JJ
cord-009417-458rrhcm	256	14	volume	volume	NN
cord-009417-458rrhcm	256	15	than	than	IN
cord-009417-458rrhcm	256	16	the	the	DT
cord-009417-458rrhcm	256	17	equivalent	equivalent	JJ
cord-009417-458rrhcm	256	18	dose	dose	NN
cord-009417-458rrhcm	256	19	of	of	IN
cord-009417-458rrhcm	256	20	FFP	FFP	NNP
cord-009417-458rrhcm	256	21	does	do	VBZ
cord-009417-458rrhcm	256	22	.	.	.
cord-009417-458rrhcm	257	1	It	-PRON-	PRP
cord-009417-458rrhcm	257	2	has	have	VBZ
cord-009417-458rrhcm	257	3	been	be	VBN
cord-009417-458rrhcm	257	4	used	use	VBN
cord-009417-458rrhcm	257	5	to	to	TO
cord-009417-458rrhcm	257	6	treat	treat	VB
cord-009417-458rrhcm	257	7	patients	patient	NNS
cord-009417-458rrhcm	257	8	with	with	IN
cord-009417-458rrhcm	257	9	inherited	inherit	VBN
cord-009417-458rrhcm	257	10	coagulopathies	coagulopathie	NNS
cord-009417-458rrhcm	257	11	,	,	,
cord-009417-458rrhcm	257	12	such	such	JJ
cord-009417-458rrhcm	257	13	as	as	IN
cord-009417-458rrhcm	257	14	hemophilia	hemophilia	NN
cord-009417-458rrhcm	257	15	A	A	NNP
cord-009417-458rrhcm	257	16	,	,	,
cord-009417-458rrhcm	257	17	von	von	NNP
cord-009417-458rrhcm	257	18	Willebrand	Willebrand	NNP
cord-009417-458rrhcm	257	19	disease	disease	NN
cord-009417-458rrhcm	257	20	,	,	,
cord-009417-458rrhcm	257	21	or	or	CC
cord-009417-458rrhcm	257	22	factor	factor	NN
cord-009417-458rrhcm	257	23	XIII	XIII	NNP
cord-009417-458rrhcm	257	24	defi	defi	NNP
cord-009417-458rrhcm	257	25	ciency	ciency	NNP
cord-009417-458rrhcm	257	26	.	.	.
cord-009417-458rrhcm	258	1	In	in	IN
cord-009417-458rrhcm	258	2	the	the	DT
cord-009417-458rrhcm	258	3	critical	critical	JJ
cord-009417-458rrhcm	258	4	care	care	NN
cord-009417-458rrhcm	258	5	setting	setting	NN
cord-009417-458rrhcm	258	6	,	,	,
cord-009417-458rrhcm	258	7	it	-PRON-	PRP
cord-009417-458rrhcm	258	8	is	be	VBZ
cord-009417-458rrhcm	258	9	more	more	RBR
cord-009417-458rrhcm	258	10	commonly	commonly	RB
cord-009417-458rrhcm	258	11	used	use	VBN
cord-009417-458rrhcm	258	12	to	to	TO
cord-009417-458rrhcm	258	13	replenish	replenish	VB
cord-009417-458rrhcm	258	14	fi	fi	NNP
cord-009417-458rrhcm	258	15	brinogen	brinogen	NNP
cord-009417-458rrhcm	258	16	,	,	,
cord-009417-458rrhcm	258	17	especially	especially	RB
cord-009417-458rrhcm	258	18	in	in	IN
cord-009417-458rrhcm	258	19	bleeding	bleed	VBG
cord-009417-458rrhcm	258	20	patients	patient	NNS
cord-009417-458rrhcm	258	21	with	with	IN
cord-009417-458rrhcm	258	22	hypofi	hypofi	NNP
cord-009417-458rrhcm	258	23	brinogenemia	brinogenemia	NN
cord-009417-458rrhcm	258	24	caused	cause	VBN
cord-009417-458rrhcm	258	25	by	by	IN
cord-009417-458rrhcm	258	26	dilutional	dilutional	JJ
cord-009417-458rrhcm	258	27	or	or	CC
cord-009417-458rrhcm	258	28	consumptive	consumptive	JJ
cord-009417-458rrhcm	258	29	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	258	30	.	.	.
cord-009417-458rrhcm	259	1	Cryoprecipitate	Cryoprecipitate	NNP
cord-009417-458rrhcm	259	2	also	also	RB
cord-009417-458rrhcm	259	3	reportedly	reportedly	RB
cord-009417-458rrhcm	259	4	improves	improve	VBZ
cord-009417-458rrhcm	259	5	hemostasis	hemostasis	NN
cord-009417-458rrhcm	259	6	in	in	IN
cord-009417-458rrhcm	259	7	uremic	uremic	JJ
cord-009417-458rrhcm	259	8	patients	patient	NNS
cord-009417-458rrhcm	259	9	,	,	,
cord-009417-458rrhcm	259	10	presumably	presumably	RB
cord-009417-458rrhcm	259	11	by	by	IN
cord-009417-458rrhcm	259	12	reversing	reverse	VBG
cord-009417-458rrhcm	259	13	the	the	DT
cord-009417-458rrhcm	259	14	functional	functional	JJ
cord-009417-458rrhcm	259	15	platelet	platelet	NN
cord-009417-458rrhcm	259	16	defect	defect	NN
cord-009417-458rrhcm	259	17	,	,	,
cord-009417-458rrhcm	259	18	60	60	CD
cord-009417-458rrhcm	259	19	but	but	CC
cord-009417-458rrhcm	259	20	desmopressin	desmopressin	NN
cord-009417-458rrhcm	259	21	acetate	acetate	NN
cord-009417-458rrhcm	259	22	(	(	-LRB-
cord-009417-458rrhcm	259	23	DDAVP	DDAVP	NNP
cord-009417-458rrhcm	259	24	)	)	-RRB-
cord-009417-458rrhcm	259	25	61	61	CD
cord-009417-458rrhcm	259	26	or	or	CC
cord-009417-458rrhcm	259	27	conjugated	conjugate	VBN
cord-009417-458rrhcm	259	28	estrogens	estrogen	NNS
cord-009417-458rrhcm	259	29	exert	exert	VBP
cord-009417-458rrhcm	259	30	similar	similar	JJ
cord-009417-458rrhcm	259	31	effects	effect	NNS
cord-009417-458rrhcm	259	32	and	and	CC
cord-009417-458rrhcm	259	33	should	should	MD
cord-009417-458rrhcm	259	34	be	be	VB
cord-009417-458rrhcm	259	35	used	use	VBN
cord-009417-458rrhcm	259	36	preferentially	preferentially	RB
cord-009417-458rrhcm	259	37	to	to	TO
cord-009417-458rrhcm	259	38	avoid	avoid	VB
cord-009417-458rrhcm	259	39	potential	potential	JJ
cord-009417-458rrhcm	259	40	transfusion	transfusion	NN
cord-009417-458rrhcm	259	41	-	-	HYPH
cord-009417-458rrhcm	259	42	transmitted	transmit	VBN
cord-009417-458rrhcm	259	43	disease	disease	NN
cord-009417-458rrhcm	259	44	.	.	.
cord-009417-458rrhcm	260	1	The	the	DT
cord-009417-458rrhcm	260	2	usual	usual	JJ
cord-009417-458rrhcm	260	3	dose	dose	NN
cord-009417-458rrhcm	260	4	of	of	IN
cord-009417-458rrhcm	260	5	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	260	6	to	to	TO
cord-009417-458rrhcm	260	7	treat	treat	VB
cord-009417-458rrhcm	260	8	hypofi	hypofi	NNP
cord-009417-458rrhcm	260	9	brinogenemia	brinogenemia	NN
cord-009417-458rrhcm	260	10	is	be	VBZ
cord-009417-458rrhcm	260	11	10	10	CD
cord-009417-458rrhcm	260	12	bags	bag	NNS
cord-009417-458rrhcm	260	13	/	/	SYM
cord-009417-458rrhcm	260	14	units	unit	NNS
cord-009417-458rrhcm	260	15	to	to	TO
cord-009417-458rrhcm	260	16	start	start	VB
cord-009417-458rrhcm	260	17	,	,	,
cord-009417-458rrhcm	260	18	then	then	RB
cord-009417-458rrhcm	260	19	6	6	CD
cord-009417-458rrhcm	260	20	to	to	TO
cord-009417-458rrhcm	260	21	10	10	CD
cord-009417-458rrhcm	260	22	bags	bag	NNS
cord-009417-458rrhcm	260	23	/	/	SYM
cord-009417-458rrhcm	260	24	units	unit	NNS
cord-009417-458rrhcm	260	25	every	every	DT
cord-009417-458rrhcm	260	26	8	8	CD
cord-009417-458rrhcm	260	27	hours	hour	NNS
cord-009417-458rrhcm	260	28	or	or	CC
cord-009417-458rrhcm	260	29	as	as	RB
cord-009417-458rrhcm	260	30	necessary	necessary	JJ
cord-009417-458rrhcm	260	31	to	to	TO
cord-009417-458rrhcm	260	32	keep	keep	VB
cord-009417-458rrhcm	260	33	the	the	DT
cord-009417-458rrhcm	260	34	fi	fi	NNP
cord-009417-458rrhcm	260	35	brinogen	brinogen	NNP
cord-009417-458rrhcm	260	36	level	level	NN
cord-009417-458rrhcm	260	37	above	above	IN
cord-009417-458rrhcm	260	38	100	100	CD
cord-009417-458rrhcm	260	39	mg	mg	NNS
cord-009417-458rrhcm	260	40	/	/	SYM
cord-009417-458rrhcm	260	41	dL.	dL.	NNS
cord-009417-458rrhcm	261	1	Each	each	DT
cord-009417-458rrhcm	261	2	bag	bag	NN
cord-009417-458rrhcm	261	3	/	/	SYM
cord-009417-458rrhcm	261	4	unit	unit	NN
cord-009417-458rrhcm	261	5	of	of	IN
cord-009417-458rrhcm	261	6	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	261	7	carries	carry	VBZ
cord-009417-458rrhcm	261	8	a	a	DT
cord-009417-458rrhcm	261	9	risk	risk	NN
cord-009417-458rrhcm	261	10	of	of	IN
cord-009417-458rrhcm	261	11	disease	disease	NN
cord-009417-458rrhcm	261	12	transmission	transmission	NN
cord-009417-458rrhcm	261	13	equivalent	equivalent	JJ
cord-009417-458rrhcm	261	14	to	to	IN
cord-009417-458rrhcm	261	15	that	that	DT
cord-009417-458rrhcm	261	16	of	of	IN
cord-009417-458rrhcm	261	17	1	1	CD
cord-009417-458rrhcm	261	18	unit	unit	NN
cord-009417-458rrhcm	261	19	of	of	IN
cord-009417-458rrhcm	261	20	blood	blood	NN
cord-009417-458rrhcm	261	21	.	.	.
cord-009417-458rrhcm	262	1	For	for	IN
cord-009417-458rrhcm	262	2	this	this	DT
cord-009417-458rrhcm	262	3	reason	reason	NN
cord-009417-458rrhcm	262	4	,	,	,
cord-009417-458rrhcm	262	5	commercial	commercial	JJ
cord-009417-458rrhcm	262	6	factor	factor	NN
cord-009417-458rrhcm	262	7	VIII	VIII	NNP
cord-009417-458rrhcm	262	8	concentrates	concentrate	VBZ
cord-009417-458rrhcm	262	9	,	,	,
cord-009417-458rrhcm	262	10	recombinant	recombinant	JJ
cord-009417-458rrhcm	262	11	or	or	CC
cord-009417-458rrhcm	262	12	treated	treat	VBN
cord-009417-458rrhcm	262	13	to	to	TO
cord-009417-458rrhcm	262	14	inactivate	inactivate	VB
cord-009417-458rrhcm	262	15	viruses	virus	NNS
cord-009417-458rrhcm	262	16	,	,	,
cord-009417-458rrhcm	262	17	are	be	VBP
cord-009417-458rrhcm	262	18	preferred	prefer	VBN
cord-009417-458rrhcm	262	19	over	over	IN
cord-009417-458rrhcm	262	20	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	262	21	for	for	IN
cord-009417-458rrhcm	262	22	treating	treat	VBG
cord-009417-458rrhcm	262	23	hemophilia	hemophilia	NN
cord-009417-458rrhcm	262	24	A	a	DT
cord-009417-458rrhcm	262	25	patients	patient	NNS
cord-009417-458rrhcm	262	26	.	.	.
cord-009417-458rrhcm	263	1	Immune	immune	JJ
cord-009417-458rrhcm	263	2	serum	serum	NN
cord-009417-458rrhcm	263	3	globulin	globulin	NN
cord-009417-458rrhcm	263	4	(	(	-LRB-
cord-009417-458rrhcm	263	5	IG	IG	NNP
cord-009417-458rrhcm	263	6	)	)	-RRB-
cord-009417-458rrhcm	263	7	,	,	,
cord-009417-458rrhcm	263	8	RhIG	rhig	NN
cord-009417-458rrhcm	263	9	,	,	,
cord-009417-458rrhcm	263	10	and	and	CC
cord-009417-458rrhcm	263	11	hyperimmune	hyperimmune	NNP
cord-009417-458rrhcm	263	12	globulins	globulin	NNS
cord-009417-458rrhcm	263	13	for	for	IN
cord-009417-458rrhcm	263	14	diseases	disease	NNS
cord-009417-458rrhcm	263	15	such	such	JJ
cord-009417-458rrhcm	263	16	as	as	IN
cord-009417-458rrhcm	263	17	hepatitis	hepatitis	NN
cord-009417-458rrhcm	263	18	B	B	NNP
cord-009417-458rrhcm	263	19	and	and	CC
cord-009417-458rrhcm	263	20	varicella	varicella	NN
cord-009417-458rrhcm	263	21	zoster	zoster	NN
cord-009417-458rrhcm	263	22	are	be	VBP
cord-009417-458rrhcm	263	23	obtained	obtain	VBN
cord-009417-458rrhcm	263	24	by	by	IN
cord-009417-458rrhcm	263	25	fractionation	fractionation	NN
cord-009417-458rrhcm	263	26	of	of	IN
cord-009417-458rrhcm	263	27	pooled	pool	VBN
cord-009417-458rrhcm	263	28	plasma	plasma	NN
cord-009417-458rrhcm	263	29	,	,	,
cord-009417-458rrhcm	263	30	followed	follow	VBN
cord-009417-458rrhcm	263	31	by	by	IN
cord-009417-458rrhcm	263	32	chromatography	chromatography	NN
cord-009417-458rrhcm	263	33	,	,	,
cord-009417-458rrhcm	263	34	delipidation	delipidation	NN
cord-009417-458rrhcm	263	35	,	,	,
cord-009417-458rrhcm	263	36	and	and	CC
cord-009417-458rrhcm	263	37	other	other	JJ
cord-009417-458rrhcm	263	38	steps	step	NNS
cord-009417-458rrhcm	263	39	to	to	TO
cord-009417-458rrhcm	263	40	remove	remove	VB
cord-009417-458rrhcm	263	41	aggregates	aggregate	NNS
cord-009417-458rrhcm	263	42	and	and	CC
cord-009417-458rrhcm	263	43	infectious	infectious	JJ
cord-009417-458rrhcm	263	44	agents	agent	NNS
cord-009417-458rrhcm	263	45	.	.	.
cord-009417-458rrhcm	264	1	Intravenous	intravenous	JJ
cord-009417-458rrhcm	264	2	IG	ig	NN
cord-009417-458rrhcm	264	3	(	(	-LRB-
cord-009417-458rrhcm	264	4	IVIG	IVIG	NNP
cord-009417-458rrhcm	264	5	)	)	-RRB-
cord-009417-458rrhcm	264	6	is	be	VBZ
cord-009417-458rrhcm	264	7	available	available	JJ
cord-009417-458rrhcm	264	8	in	in	IN
cord-009417-458rrhcm	264	9	solution	solution	NN
cord-009417-458rrhcm	264	10	or	or	CC
cord-009417-458rrhcm	264	11	lyophilized	lyophilize	VBN
cord-009417-458rrhcm	264	12	form	form	NN
cord-009417-458rrhcm	264	13	,	,	,
cord-009417-458rrhcm	264	14	with	with	IN
cord-009417-458rrhcm	264	15	protein	protein	NN
cord-009417-458rrhcm	264	16	content	content	NN
cord-009417-458rrhcm	264	17	varying	vary	VBG
cord-009417-458rrhcm	264	18	by	by	IN
cord-009417-458rrhcm	264	19	mode	mode	NN
cord-009417-458rrhcm	264	20	of	of	IN
cord-009417-458rrhcm	264	21	preparation	preparation	NN
cord-009417-458rrhcm	264	22	.	.	.
cord-009417-458rrhcm	265	1	The	the	DT
cord-009417-458rrhcm	265	2	available	available	JJ
cord-009417-458rrhcm	265	3	products	product	NNS
cord-009417-458rrhcm	265	4	vary	vary	VBP
cord-009417-458rrhcm	265	5	slightly	slightly	RB
cord-009417-458rrhcm	265	6	in	in	IN
cord-009417-458rrhcm	265	7	the	the	DT
cord-009417-458rrhcm	265	8	amounts	amount	NNS
cord-009417-458rrhcm	265	9	of	of	IN
cord-009417-458rrhcm	265	10	IgA	IgA	NNP
cord-009417-458rrhcm	265	11	and	and	CC
cord-009417-458rrhcm	265	12	IgM	IgM	NNP
cord-009417-458rrhcm	265	13	contained	contain	VBD
cord-009417-458rrhcm	265	14	in	in	IN
cord-009417-458rrhcm	265	15	them	-PRON-	PRP
cord-009417-458rrhcm	265	16	,	,	,
cord-009417-458rrhcm	265	17	which	which	WDT
cord-009417-458rrhcm	265	18	are	be	VBP
cord-009417-458rrhcm	265	19	mostly	mostly	RB
cord-009417-458rrhcm	265	20	present	present	JJ
cord-009417-458rrhcm	265	21	in	in	IN
cord-009417-458rrhcm	265	22	only	only	JJ
cord-009417-458rrhcm	265	23	trace	trace	NN
cord-009417-458rrhcm	265	24	quantities	quantity	NNS
cord-009417-458rrhcm	265	25	.	.	.
cord-009417-458rrhcm	266	1	IG	IG	NNP
cord-009417-458rrhcm	266	2	preparations	preparation	NNS
cord-009417-458rrhcm	266	3	can	can	MD
cord-009417-458rrhcm	266	4	be	be	VB
cord-009417-458rrhcm	266	5	used	use	VBN
cord-009417-458rrhcm	266	6	to	to	TO
cord-009417-458rrhcm	266	7	provide	provide	VB
cord-009417-458rrhcm	266	8	passive	passive	JJ
cord-009417-458rrhcm	266	9	antibody	antibody	NN
cord-009417-458rrhcm	266	10	prophylaxis	prophylaxis	NN
cord-009417-458rrhcm	266	11	or	or	CC
cord-009417-458rrhcm	266	12	to	to	TO
cord-009417-458rrhcm	266	13	supply	supply	VB
cord-009417-458rrhcm	266	14	IG	ig	NN
cord-009417-458rrhcm	266	15	in	in	IN
cord-009417-458rrhcm	266	16	certain	certain	JJ
cord-009417-458rrhcm	266	17	immunodeficiency	immunodeficiency	NN
cord-009417-458rrhcm	266	18	states	state	NNS
cord-009417-458rrhcm	266	19	.	.	.
cord-009417-458rrhcm	267	1	Hyperimmune	Hyperimmune	NNP
cord-009417-458rrhcm	267	2	globulins	globulin	NNS
cord-009417-458rrhcm	267	3	may	may	MD
cord-009417-458rrhcm	267	4	be	be	VB
cord-009417-458rrhcm	267	5	used	use	VBN
cord-009417-458rrhcm	267	6	to	to	TO
cord-009417-458rrhcm	267	7	treat	treat	VB
cord-009417-458rrhcm	267	8	active	active	JJ
cord-009417-458rrhcm	267	9	infections	infection	NNS
cord-009417-458rrhcm	267	10	in	in	IN
cord-009417-458rrhcm	267	11	immunosuppressed	immunosuppressed	JJ
cord-009417-458rrhcm	267	12	hosts	host	NNS
cord-009417-458rrhcm	267	13	.	.	.
cord-009417-458rrhcm	268	1	Recent	recent	JJ
cord-009417-458rrhcm	268	2	applications	application	NNS
cord-009417-458rrhcm	268	3	have	have	VBP
cord-009417-458rrhcm	268	4	exploited	exploit	VBN
cord-009417-458rrhcm	268	5	IG	IG	NNP
cord-009417-458rrhcm	268	6	's	's	POS
cord-009417-458rrhcm	268	7	immunomodulatory	immunomodulatory	JJ
cord-009417-458rrhcm	268	8	effects	effect	NNS
cord-009417-458rrhcm	268	9	in	in	IN
cord-009417-458rrhcm	268	10	treating	treat	VBG
cord-009417-458rrhcm	268	11	a	a	DT
cord-009417-458rrhcm	268	12	wide	wide	JJ
cord-009417-458rrhcm	268	13	variety	variety	NN
cord-009417-458rrhcm	268	14	of	of	IN
cord-009417-458rrhcm	268	15	disorders	disorder	NNS
cord-009417-458rrhcm	268	16	with	with	IN
cord-009417-458rrhcm	268	17	an	an	DT
cord-009417-458rrhcm	268	18	immune	immune	JJ
cord-009417-458rrhcm	268	19	basis	basis	NN
cord-009417-458rrhcm	268	20	.	.	.
cord-009417-458rrhcm	269	1	The	the	DT
cord-009417-458rrhcm	269	2	specifi	specifi	NN
cord-009417-458rrhcm	269	3	c	c	NN
cord-009417-458rrhcm	269	4	mechanism	mechanism	NN
cord-009417-458rrhcm	269	5	of	of	IN
cord-009417-458rrhcm	269	6	action	action	NN
cord-009417-458rrhcm	269	7	of	of	IN
cord-009417-458rrhcm	269	8	IVIG	IVIG	NNP
cord-009417-458rrhcm	269	9	in	in	IN
cord-009417-458rrhcm	269	10	such	such	JJ
cord-009417-458rrhcm	269	11	conditions	condition	NNS
cord-009417-458rrhcm	269	12	has	have	VBZ
cord-009417-458rrhcm	269	13	not	not	RB
cord-009417-458rrhcm	269	14	yet	yet	RB
cord-009417-458rrhcm	269	15	been	be	VBN
cord-009417-458rrhcm	269	16	identifi	identifi	VBN
cord-009417-458rrhcm	269	17	ed	ed	NN
cord-009417-458rrhcm	269	18	,	,	,
cord-009417-458rrhcm	269	19	but	but	CC
cord-009417-458rrhcm	269	20	possibilities	possibility	NNS
cord-009417-458rrhcm	269	21	include	include	VBP
cord-009417-458rrhcm	269	22	interference	interference	NN
cord-009417-458rrhcm	269	23	with	with	IN
cord-009417-458rrhcm	269	24	macrophage	macrophage	NN
cord-009417-458rrhcm	269	25	Fc	Fc	NNP
cord-009417-458rrhcm	269	26	receptor	receptor	NN
cord-009417-458rrhcm	269	27	function	function	NN
cord-009417-458rrhcm	269	28	,	,	,
cord-009417-458rrhcm	269	29	neutralization	neutralization	NN
cord-009417-458rrhcm	269	30	of	of	IN
cord-009417-458rrhcm	269	31	anti	anti	JJ
cord-009417-458rrhcm	269	32	-	-	JJ
cord-009417-458rrhcm	269	33	idiotypic	idiotypic	JJ
cord-009417-458rrhcm	269	34	antibodies	antibody	NNS
cord-009417-458rrhcm	269	35	,	,	,
cord-009417-458rrhcm	269	36	and	and	CC
cord-009417-458rrhcm	269	37	interference	interference	NN
cord-009417-458rrhcm	269	38	with	with	IN
cord-009417-458rrhcm	269	39	the	the	DT
cord-009417-458rrhcm	269	40	incorporation	incorporation	NN
cord-009417-458rrhcm	269	41	of	of	IN
cord-009417-458rrhcm	269	42	activated	activate	VBN
cord-009417-458rrhcm	269	43	complement	complement	NN
cord-009417-458rrhcm	269	44	fragments	fragment	NNS
cord-009417-458rrhcm	269	45	into	into	IN
cord-009417-458rrhcm	269	46	immune	immune	JJ
cord-009417-458rrhcm	269	47	complexes	complex	NNS
cord-009417-458rrhcm	269	48	.	.	.
cord-009417-458rrhcm	270	1	A	a	DT
cord-009417-458rrhcm	270	2	recent	recent	JJ
cord-009417-458rrhcm	270	3	review	review	NN
cord-009417-458rrhcm	270	4	more	more	RBR
cord-009417-458rrhcm	270	5	completely	completely	RB
cord-009417-458rrhcm	270	6	discusses	discuss	VBZ
cord-009417-458rrhcm	270	7	the	the	DT
cord-009417-458rrhcm	270	8	effects	effect	NNS
cord-009417-458rrhcm	270	9	of	of	IN
cord-009417-458rrhcm	270	10	IVIG	IVIG	NNP
cord-009417-458rrhcm	270	11	on	on	IN
cord-009417-458rrhcm	270	12	the	the	DT
cord-009417-458rrhcm	270	13	immune	immune	JJ
cord-009417-458rrhcm	270	14	system	system	NN
cord-009417-458rrhcm	270	15	and	and	CC
cord-009417-458rrhcm	270	16	its	-PRON-	PRP$
cord-009417-458rrhcm	270	17	potential	potential	JJ
cord-009417-458rrhcm	270	18	uses	use	NNS
cord-009417-458rrhcm	270	19	.	.	.
cord-009417-458rrhcm	271	1	62	62	CD
cord-009417-458rrhcm	271	2	RhIG	rhig	NN
cord-009417-458rrhcm	271	3	is	be	VBZ
cord-009417-458rrhcm	271	4	prepared	prepare	VBN
cord-009417-458rrhcm	271	5	from	from	IN
cord-009417-458rrhcm	271	6	pools	pool	NNS
cord-009417-458rrhcm	271	7	of	of	IN
cord-009417-458rrhcm	271	8	plasma	plasma	NN
cord-009417-458rrhcm	271	9	obtained	obtain	VBN
cord-009417-458rrhcm	271	10	from	from	IN
cord-009417-458rrhcm	271	11	donors	donor	NNS
cord-009417-458rrhcm	271	12	sensitized	sensitize	VBN
cord-009417-458rrhcm	271	13	to	to	IN
cord-009417-458rrhcm	271	14	the	the	DT
cord-009417-458rrhcm	271	15	red	red	JJ
cord-009417-458rrhcm	271	16	cell	cell	NN
cord-009417-458rrhcm	271	17	antigen	antigen	NN
cord-009417-458rrhcm	271	18	D	d	NN
cord-009417-458rrhcm	271	19	from	from	IN
cord-009417-458rrhcm	271	20	the	the	DT
cord-009417-458rrhcm	271	21	Rh	Rh	NNP
cord-009417-458rrhcm	271	22	group	group	NN
cord-009417-458rrhcm	271	23	.	.	.
cord-009417-458rrhcm	272	1	The	the	DT
cord-009417-458rrhcm	272	2	standard	standard	JJ
cord-009417-458rrhcm	272	3	-	-	HYPH
cord-009417-458rrhcm	272	4	dose	dose	NN
cord-009417-458rrhcm	272	5	vial	vial	NN
cord-009417-458rrhcm	272	6	contains	contain	VBZ
cord-009417-458rrhcm	272	7	primarily	primarily	RB
cord-009417-458rrhcm	272	8	IgG	IgG	NNP
cord-009417-458rrhcm	272	9	anti	anti	NNP
cord-009417-458rrhcm	272	10	-	-	NNP
cord-009417-458rrhcm	272	11	D	d	JJ
cord-009417-458rrhcm	272	12	,	,	,
cord-009417-458rrhcm	272	13	with	with	IN
cord-009417-458rrhcm	272	14	a	a	DT
cord-009417-458rrhcm	272	15	protein	protein	NN
cord-009417-458rrhcm	272	16	content	content	NN
cord-009417-458rrhcm	272	17	of	of	IN
cord-009417-458rrhcm	272	18	300	300	CD
cord-009417-458rrhcm	272	19	µg	µg	NN
cord-009417-458rrhcm	272	20	in	in	IN
cord-009417-458rrhcm	272	21	1	1	CD
cord-009417-458rrhcm	272	22	mL.	mL.	NNS
cord-009417-458rrhcm	272	23	This	this	DT
cord-009417-458rrhcm	272	24	dose	dose	NN
cord-009417-458rrhcm	272	25	will	will	MD
cord-009417-458rrhcm	272	26	protect	protect	VB
cord-009417-458rrhcm	272	27	against	against	IN
cord-009417-458rrhcm	272	28	15	15	CD
cord-009417-458rrhcm	272	29	mL	mL	NNS
cord-009417-458rrhcm	272	30	of	of	IN
cord-009417-458rrhcm	272	31	D	D	NNP
cord-009417-458rrhcm	272	32	+	+	CC
cord-009417-458rrhcm	272	33	red	red	JJ
cord-009417-458rrhcm	272	34	cells	cell	NNS
cord-009417-458rrhcm	272	35	or	or	CC
cord-009417-458rrhcm	272	36	30	30	CD
cord-009417-458rrhcm	272	37	mL	ml	NN
cord-009417-458rrhcm	272	38	of	of	IN
cord-009417-458rrhcm	272	39	WB	WB	NNP
cord-009417-458rrhcm	272	40	.	.	.
cord-009417-458rrhcm	273	1	63	63	CD
cord-009417-458rrhcm	273	2	RhIG	rhig	NN
cord-009417-458rrhcm	273	3	carries	carry	VBZ
cord-009417-458rrhcm	273	4	no	no	DT
cord-009417-458rrhcm	273	5	risk	risk	NN
cord-009417-458rrhcm	273	6	of	of	IN
cord-009417-458rrhcm	273	7	virus	virus	NN
cord-009417-458rrhcm	273	8	transmission	transmission	NN
cord-009417-458rrhcm	273	9	.	.	.
cord-009417-458rrhcm	274	1	Although	although	IN
cord-009417-458rrhcm	274	2	RhIG	rhig	NN
cord-009417-458rrhcm	274	3	is	be	VBZ
cord-009417-458rrhcm	274	4	used	use	VBN
cord-009417-458rrhcm	274	5	primarily	primarily	RB
cord-009417-458rrhcm	274	6	in	in	IN
cord-009417-458rrhcm	274	7	obstetrics	obstetric	NNS
cord-009417-458rrhcm	274	8	,	,	,
cord-009417-458rrhcm	274	9	it	-PRON-	PRP
cord-009417-458rrhcm	274	10	may	may	MD
cord-009417-458rrhcm	274	11	also	also	RB
cord-009417-458rrhcm	274	12	be	be	VB
cord-009417-458rrhcm	274	13	indicated	indicate	VBN
cord-009417-458rrhcm	274	14	to	to	TO
cord-009417-458rrhcm	274	15	prevent	prevent	VB
cord-009417-458rrhcm	274	16	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	274	17	in	in	IN
cord-009417-458rrhcm	274	18	Rh	Rh	NNP
cord-009417-458rrhcm	274	19	-	-	HYPH
cord-009417-458rrhcm	274	20	negative	negative	JJ
cord-009417-458rrhcm	274	21	patients	patient	NNS
cord-009417-458rrhcm	274	22	receiving	receive	VBG
cord-009417-458rrhcm	274	23	small	small	JJ
cord-009417-458rrhcm	274	24	amounts	amount	NNS
cord-009417-458rrhcm	274	25	of	of	IN
cord-009417-458rrhcm	274	26	Rh	Rh	NNP
cord-009417-458rrhcm	274	27	-	-	HYPH
cord-009417-458rrhcm	274	28	positive	positive	JJ
cord-009417-458rrhcm	274	29	red	red	JJ
cord-009417-458rrhcm	274	30	cells	cell	NNS
cord-009417-458rrhcm	274	31	,	,	,
cord-009417-458rrhcm	274	32	as	as	IN
cord-009417-458rrhcm	274	33	in	in	IN
cord-009417-458rrhcm	274	34	platelet	platelet	NN
cord-009417-458rrhcm	274	35	concentrates	concentrate	VBZ
cord-009417-458rrhcm	274	36	.	.	.
cord-009417-458rrhcm	275	1	Routine	routine	JJ
cord-009417-458rrhcm	275	2	prophylaxis	prophylaxis	NN
cord-009417-458rrhcm	275	3	against	against	IN
cord-009417-458rrhcm	275	4	large	large	JJ
cord-009417-458rrhcm	275	5	numbers	number	NNS
cord-009417-458rrhcm	275	6	of	of	IN
cord-009417-458rrhcm	275	7	red	red	JJ
cord-009417-458rrhcm	275	8	cells	cell	NNS
cord-009417-458rrhcm	275	9	,	,	,
cord-009417-458rrhcm	275	10	as	as	IN
cord-009417-458rrhcm	275	11	in	in	IN
cord-009417-458rrhcm	275	12	a	a	DT
cord-009417-458rrhcm	275	13	unit	unit	NN
cord-009417-458rrhcm	275	14	of	of	IN
cord-009417-458rrhcm	275	15	Rh	Rh	NNP
cord-009417-458rrhcm	275	16	-	-	HYPH
cord-009417-458rrhcm	275	17	positive	positive	JJ
cord-009417-458rrhcm	275	18	WB	WB	NNP
cord-009417-458rrhcm	275	19	or	or	CC
cord-009417-458rrhcm	275	20	PRBCs	prbc	NNS
cord-009417-458rrhcm	275	21	given	give	VBN
cord-009417-458rrhcm	275	22	by	by	IN
cord-009417-458rrhcm	275	23	accident	accident	NN
cord-009417-458rrhcm	275	24	to	to	IN
cord-009417-458rrhcm	275	25	an	an	DT
cord-009417-458rrhcm	275	26	Rh	Rh	NNP
cord-009417-458rrhcm	275	27	-	-	HYPH
cord-009417-458rrhcm	275	28	negative	negative	JJ
cord-009417-458rrhcm	275	29	recipient	recipient	NN
cord-009417-458rrhcm	275	30	,	,	,
cord-009417-458rrhcm	275	31	is	be	VBZ
cord-009417-458rrhcm	275	32	not	not	RB
cord-009417-458rrhcm	275	33	reliable	reliable	JJ
cord-009417-458rrhcm	275	34	and	and	CC
cord-009417-458rrhcm	275	35	usually	usually	RB
cord-009417-458rrhcm	275	36	involves	involve	VBZ
cord-009417-458rrhcm	275	37	the	the	DT
cord-009417-458rrhcm	275	38	administration	administration	NN
cord-009417-458rrhcm	275	39	of	of	IN
cord-009417-458rrhcm	275	40	large	large	JJ
cord-009417-458rrhcm	275	41	amounts	amount	NNS
cord-009417-458rrhcm	275	42	,	,	,
cord-009417-458rrhcm	275	43	but	but	CC
cord-009417-458rrhcm	275	44	instances	instance	NNS
cord-009417-458rrhcm	275	45	of	of	IN
cord-009417-458rrhcm	275	46	its	-PRON-	PRP$
cord-009417-458rrhcm	275	47	effective	effective	JJ
cord-009417-458rrhcm	275	48	use	use	NN
cord-009417-458rrhcm	275	49	in	in	IN
cord-009417-458rrhcm	275	50	these	these	DT
cord-009417-458rrhcm	275	51	circumstances	circumstance	NNS
cord-009417-458rrhcm	275	52	have	have	VBP
cord-009417-458rrhcm	275	53	been	be	VBN
cord-009417-458rrhcm	275	54	reported	report	VBN
cord-009417-458rrhcm	275	55	.	.	.
cord-009417-458rrhcm	276	1	Higher	high	JJR
cord-009417-458rrhcm	276	2	doses	dose	NNS
cord-009417-458rrhcm	276	3	of	of	IN
cord-009417-458rrhcm	276	4	intravenous	intravenous	JJ
cord-009417-458rrhcm	276	5	RhIG	rhig	NN
cord-009417-458rrhcm	276	6	have	have	VBP
cord-009417-458rrhcm	276	7	been	be	VBN
cord-009417-458rrhcm	276	8	used	use	VBN
cord-009417-458rrhcm	276	9	in	in	IN
cord-009417-458rrhcm	276	10	the	the	DT
cord-009417-458rrhcm	276	11	treatment	treatment	NN
cord-009417-458rrhcm	276	12	of	of	IN
cord-009417-458rrhcm	276	13	ITP	ITP	NNP
cord-009417-458rrhcm	276	14	.	.	.
cord-009417-458rrhcm	277	1	Plasma	plasma	NN
cord-009417-458rrhcm	277	2	-	-	HYPH
cord-009417-458rrhcm	277	3	derived	derive	VBN
cord-009417-458rrhcm	277	4	colloids	colloid	NNS
cord-009417-458rrhcm	277	5	include	include	VBP
cord-009417-458rrhcm	277	6	human	human	JJ
cord-009417-458rrhcm	277	7	serum	serum	NN
cord-009417-458rrhcm	277	8	albumin	albumin	NN
cord-009417-458rrhcm	277	9	(	(	-LRB-
cord-009417-458rrhcm	277	10	HSA	HSA	NNP
cord-009417-458rrhcm	277	11	)	)	-RRB-
cord-009417-458rrhcm	277	12	,	,	,
cord-009417-458rrhcm	277	13	available	available	JJ
cord-009417-458rrhcm	277	14	in	in	IN
cord-009417-458rrhcm	277	15	5	5	CD
cord-009417-458rrhcm	277	16	%	%	NN
cord-009417-458rrhcm	277	17	and	and	CC
cord-009417-458rrhcm	277	18	25	25	CD
cord-009417-458rrhcm	277	19	%	%	NN
cord-009417-458rrhcm	277	20	solutions	solution	NNS
cord-009417-458rrhcm	277	21	,	,	,
cord-009417-458rrhcm	277	22	and	and	CC
cord-009417-458rrhcm	277	23	plasma	plasma	NN
cord-009417-458rrhcm	277	24	protein	protein	NN
cord-009417-458rrhcm	277	25	fraction	fraction	NN
cord-009417-458rrhcm	277	26	(	(	-LRB-
cord-009417-458rrhcm	277	27	PPF	PPF	NNP
cord-009417-458rrhcm	277	28	)	)	-RRB-
cord-009417-458rrhcm	277	29	,	,	,
cord-009417-458rrhcm	277	30	available	available	JJ
cord-009417-458rrhcm	277	31	in	in	IN
cord-009417-458rrhcm	277	32	a	a	DT
cord-009417-458rrhcm	277	33	5	5	CD
cord-009417-458rrhcm	277	34	%	%	NN
cord-009417-458rrhcm	277	35	solution	solution	NN
cord-009417-458rrhcm	277	36	.	.	.
cord-009417-458rrhcm	278	1	Both	both	DT
cord-009417-458rrhcm	278	2	are	be	VBP
cord-009417-458rrhcm	278	3	derived	derive	VBN
cord-009417-458rrhcm	278	4	from	from	IN
cord-009417-458rrhcm	278	5	pooled	pool	VBN
cord-009417-458rrhcm	278	6	donor	donor	NN
cord-009417-458rrhcm	278	7	plasma	plasma	NN
cord-009417-458rrhcm	278	8	but	but	CC
cord-009417-458rrhcm	278	9	are	be	VBP
cord-009417-458rrhcm	278	10	essentially	essentially	RB
cord-009417-458rrhcm	278	11	pathogen	pathogen	NN
cord-009417-458rrhcm	278	12	-	-	HYPH
cord-009417-458rrhcm	278	13	free	free	JJ
cord-009417-458rrhcm	278	14	.	.	.
cord-009417-458rrhcm	279	1	HSA	HSA	NNP
cord-009417-458rrhcm	279	2	is	be	VBZ
cord-009417-458rrhcm	279	3	composed	compose	VBN
cord-009417-458rrhcm	279	4	of	of	IN
cord-009417-458rrhcm	279	5	at	at	RB
cord-009417-458rrhcm	279	6	least	least	RBS
cord-009417-458rrhcm	279	7	96	96	CD
cord-009417-458rrhcm	279	8	%	%	NN
cord-009417-458rrhcm	279	9	albumin	albumin	NN
cord-009417-458rrhcm	279	10	,	,	,
cord-009417-458rrhcm	279	11	whereas	whereas	IN
cord-009417-458rrhcm	279	12	PPF	PPF	NNP
cord-009417-458rrhcm	279	13	is	be	VBZ
cord-009417-458rrhcm	279	14	subjected	subject	VBN
cord-009417-458rrhcm	279	15	to	to	IN
cord-009417-458rrhcm	279	16	fewer	few	JJR
cord-009417-458rrhcm	279	17	purifi	purifi	NNP
cord-009417-458rrhcm	279	18	cation	cation	NN
cord-009417-458rrhcm	279	19	steps	step	NNS
cord-009417-458rrhcm	279	20	and	and	CC
cord-009417-458rrhcm	279	21	contains	contain	VBZ
cord-009417-458rrhcm	279	22	at	at	IN
cord-009417-458rrhcm	279	23	least	least	RBS
cord-009417-458rrhcm	279	24	83	83	CD
cord-009417-458rrhcm	279	25	%	%	NN
cord-009417-458rrhcm	279	26	albumin	albumin	NN
cord-009417-458rrhcm	279	27	,	,	,
cord-009417-458rrhcm	279	28	with	with	IN
cord-009417-458rrhcm	279	29	correspondingly	correspondingly	RB
cord-009417-458rrhcm	279	30	more	more	JJR
cord-009417-458rrhcm	279	31	globulins	globulin	NNS
cord-009417-458rrhcm	279	32	.	.	.
cord-009417-458rrhcm	280	1	The	the	DT
cord-009417-458rrhcm	280	2	5	5	CD
cord-009417-458rrhcm	280	3	%	%	NN
cord-009417-458rrhcm	280	4	solutions	solution	NNS
cord-009417-458rrhcm	280	5	are	be	VBP
cord-009417-458rrhcm	280	6	iso	iso	NN
cord-009417-458rrhcm	280	7	-	-	HYPH
cord-009417-458rrhcm	280	8	oncotic	oncotic	JJ
cord-009417-458rrhcm	280	9	,	,	,
cord-009417-458rrhcm	280	10	whereas	whereas	IN
cord-009417-458rrhcm	280	11	the	the	DT
cord-009417-458rrhcm	280	12	25	25	CD
cord-009417-458rrhcm	280	13	%	%	NN
cord-009417-458rrhcm	280	14	solution	solution	NN
cord-009417-458rrhcm	280	15	of	of	IN
cord-009417-458rrhcm	280	16	HSA	HSA	NNP
cord-009417-458rrhcm	280	17	is	be	VBZ
cord-009417-458rrhcm	280	18	hyperoncotic	hyperoncotic	JJ
cord-009417-458rrhcm	280	19	and	and	CC
cord-009417-458rrhcm	280	20	requires	require	VBZ
cord-009417-458rrhcm	280	21	infusion	infusion	NN
cord-009417-458rrhcm	280	22	with	with	IN
cord-009417-458rrhcm	280	23	crystalloid	crystalloid	NNP
cord-009417-458rrhcm	280	24	solutions	solution	NNS
cord-009417-458rrhcm	280	25	.	.	.
cord-009417-458rrhcm	281	1	Potential	potential	JJ
cord-009417-458rrhcm	281	2	clinical	clinical	JJ
cord-009417-458rrhcm	281	3	indications	indication	NNS
cord-009417-458rrhcm	281	4	for	for	IN
cord-009417-458rrhcm	281	5	colloid	colloid	NN
cord-009417-458rrhcm	281	6	solutions	solution	NNS
cord-009417-458rrhcm	281	7	include	include	VBP
cord-009417-458rrhcm	281	8	hypovolemic	hypovolemic	JJ
cord-009417-458rrhcm	281	9	shock	shock	NN
cord-009417-458rrhcm	281	10	,	,	,
cord-009417-458rrhcm	281	11	hypotension	hypotension	NN
cord-009417-458rrhcm	281	12	associated	associate	VBN
cord-009417-458rrhcm	281	13	with	with	IN
cord-009417-458rrhcm	281	14	hypoproteinemia	hypoproteinemia	NN
cord-009417-458rrhcm	281	15	in	in	IN
cord-009417-458rrhcm	281	16	patients	patient	NNS
cord-009417-458rrhcm	281	17	with	with	IN
cord-009417-458rrhcm	281	18	liver	liver	NN
cord-009417-458rrhcm	281	19	failure	failure	NN
cord-009417-458rrhcm	281	20	or	or	CC
cord-009417-458rrhcm	281	21	protein	protein	NN
cord-009417-458rrhcm	281	22	-	-	HYPH
cord-009417-458rrhcm	281	23	losing	lose	VBG
cord-009417-458rrhcm	281	24	conditions	condition	NNS
cord-009417-458rrhcm	281	25	,	,	,
cord-009417-458rrhcm	281	26	as	as	IN
cord-009417-458rrhcm	281	27	a	a	DT
cord-009417-458rrhcm	281	28	replacement	replacement	NN
cord-009417-458rrhcm	281	29	solution	solution	NN
cord-009417-458rrhcm	281	30	in	in	IN
cord-009417-458rrhcm	281	31	plasma	plasma	NN
cord-009417-458rrhcm	281	32	exchange	exchange	NN
cord-009417-458rrhcm	281	33	or	or	CC
cord-009417-458rrhcm	281	34	exchange	exchange	NN
cord-009417-458rrhcm	281	35	transfusion	transfusion	NN
cord-009417-458rrhcm	281	36	,	,	,
cord-009417-458rrhcm	281	37	and	and	CC
cord-009417-458rrhcm	281	38	to	to	TO
cord-009417-458rrhcm	281	39	facilitate	facilitate	VB
cord-009417-458rrhcm	281	40	diuresis	diuresis	NN
cord-009417-458rrhcm	281	41	in	in	IN
cord-009417-458rrhcm	281	42	fl	fl	NNP
cord-009417-458rrhcm	281	43	uidoverloaded	uidoverloaded	JJ
cord-009417-458rrhcm	281	44	hypoproteinemic	hypoproteinemic	NNP
cord-009417-458rrhcm	281	45	patients	patient	NNS
cord-009417-458rrhcm	281	46	.	.	.
cord-009417-458rrhcm	282	1	Albumin	albumin	NN
cord-009417-458rrhcm	282	2	solutions	solution	NNS
cord-009417-458rrhcm	282	3	are	be	VBP
cord-009417-458rrhcm	282	4	not	not	RB
cord-009417-458rrhcm	282	5	indicated	indicate	VBN
cord-009417-458rrhcm	282	6	as	as	IN
cord-009417-458rrhcm	282	7	a	a	DT
cord-009417-458rrhcm	282	8	nutritional	nutritional	JJ
cord-009417-458rrhcm	282	9	source	source	NN
cord-009417-458rrhcm	282	10	to	to	TO
cord-009417-458rrhcm	282	11	raise	raise	VB
cord-009417-458rrhcm	282	12	serum	serum	NN
cord-009417-458rrhcm	282	13	albumin	albumin	NN
cord-009417-458rrhcm	282	14	.	.	.
cord-009417-458rrhcm	283	1	Their	-PRON-	PRP$
cord-009417-458rrhcm	283	2	use	use	NN
cord-009417-458rrhcm	283	3	in	in	IN
cord-009417-458rrhcm	283	4	some	some	DT
cord-009417-458rrhcm	283	5	indications	indication	NNS
cord-009417-458rrhcm	283	6	,	,	,
cord-009417-458rrhcm	283	7	particularly	particularly	RB
cord-009417-458rrhcm	283	8	for	for	IN
cord-009417-458rrhcm	283	9	resuscitation	resuscitation	NN
cord-009417-458rrhcm	283	10	,	,	,
cord-009417-458rrhcm	283	11	has	have	VBZ
cord-009417-458rrhcm	283	12	become	become	VBN
cord-009417-458rrhcm	283	13	controversial	controversial	JJ
cord-009417-458rrhcm	283	14	,	,	,
cord-009417-458rrhcm	283	15	and	and	CC
cord-009417-458rrhcm	283	16	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	283	17	edema	edema	NN
cord-009417-458rrhcm	283	18	has	have	VBZ
cord-009417-458rrhcm	283	19	been	be	VBN
cord-009417-458rrhcm	283	20	reported	report	VBN
cord-009417-458rrhcm	283	21	in	in	IN
cord-009417-458rrhcm	283	22	association	association	NN
cord-009417-458rrhcm	283	23	with	with	IN
cord-009417-458rrhcm	283	24	their	-PRON-	PRP$
cord-009417-458rrhcm	283	25	infusion	infusion	NN
cord-009417-458rrhcm	283	26	.	.	.
cord-009417-458rrhcm	284	1	64	64	CD
cord-009417-458rrhcm	285	1	Although	although	IN
cord-009417-458rrhcm	285	2	albumin	albumin	NN
cord-009417-458rrhcm	285	3	solutions	solution	NNS
cord-009417-458rrhcm	285	4	are	be	VBP
cord-009417-458rrhcm	285	5	reasonably	reasonably	RB
cord-009417-458rrhcm	285	6	safe	safe	JJ
cord-009417-458rrhcm	285	7	products	product	NNS
cord-009417-458rrhcm	285	8	to	to	TO
cord-009417-458rrhcm	285	9	administer	administer	VB
cord-009417-458rrhcm	285	10	,	,	,
cord-009417-458rrhcm	285	11	expense	expense	NN
cord-009417-458rrhcm	285	12	and	and	CC
cord-009417-458rrhcm	285	13	limited	limited	JJ
cord-009417-458rrhcm	285	14	availability	availability	NN
cord-009417-458rrhcm	285	15	restrict	restrict	VBP
cord-009417-458rrhcm	285	16	their	-PRON-	PRP$
cord-009417-458rrhcm	285	17	use	use	NN
cord-009417-458rrhcm	285	18	.	.	.
cord-009417-458rrhcm	286	1	Anaphylactic	anaphylactic	JJ
cord-009417-458rrhcm	286	2	reactions	reaction	NNS
cord-009417-458rrhcm	286	3	have	have	VBP
cord-009417-458rrhcm	286	4	been	be	VBN
cord-009417-458rrhcm	286	5	reported	report	VBN
cord-009417-458rrhcm	286	6	in	in	IN
cord-009417-458rrhcm	286	7	less	less	JJR
cord-009417-458rrhcm	286	8	than	than	IN
cord-009417-458rrhcm	286	9	0.1	0.1	CD
cord-009417-458rrhcm	286	10	%	%	NN
cord-009417-458rrhcm	286	11	of	of	IN
cord-009417-458rrhcm	286	12	recipients	recipient	NNS
cord-009417-458rrhcm	286	13	.	.	.
cord-009417-458rrhcm	287	1	The	the	DT
cord-009417-458rrhcm	287	2	use	use	NN
cord-009417-458rrhcm	287	3	of	of	IN
cord-009417-458rrhcm	287	4	PPF	PPF	NNP
cord-009417-458rrhcm	287	5	has	have	VBZ
cord-009417-458rrhcm	287	6	been	be	VBN
cord-009417-458rrhcm	287	7	associated	associate	VBN
cord-009417-458rrhcm	287	8	with	with	IN
cord-009417-458rrhcm	287	9	severe	severe	JJ
cord-009417-458rrhcm	287	10	hypotensive	hypotensive	JJ
cord-009417-458rrhcm	287	11	episodes	episode	NNS
cord-009417-458rrhcm	287	12	,	,	,
cord-009417-458rrhcm	287	13	with	with	IN
cord-009417-458rrhcm	287	14	Hageman	Hageman	NNP
cord-009417-458rrhcm	287	15	factor	factor	NN
cord-009417-458rrhcm	287	16	fragments	fragment	NNS
cord-009417-458rrhcm	287	17	or	or	CC
cord-009417-458rrhcm	287	18	prekallikrein	prekallikrein	NN
cord-009417-458rrhcm	287	19	activator	activator	NN
cord-009417-458rrhcm	287	20	being	be	VBG
cord-009417-458rrhcm	287	21	demonstrated	demonstrate	VBN
cord-009417-458rrhcm	287	22	,	,	,
cord-009417-458rrhcm	287	23	65	65	CD
cord-009417-458rrhcm	287	24	thus	thus	RB
cord-009417-458rrhcm	287	25	making	make	VBG
cord-009417-458rrhcm	287	26	PPF	PPF	NNP
cord-009417-458rrhcm	287	27	a	a	DT
cord-009417-458rrhcm	287	28	less	less	RBR
cord-009417-458rrhcm	287	29	desirable	desirable	JJ
cord-009417-458rrhcm	287	30	resuscitation	resuscitation	NN
cord-009417-458rrhcm	287	31	fl	fl	IN
cord-009417-458rrhcm	287	32	uid	uid	NN
cord-009417-458rrhcm	287	33	and	and	CC
cord-009417-458rrhcm	287	34	contraindicated	contraindicate	VBN
cord-009417-458rrhcm	287	35	in	in	IN
cord-009417-458rrhcm	287	36	cardiac	cardiac	JJ
cord-009417-458rrhcm	287	37	surgery	surgery	NN
cord-009417-458rrhcm	287	38	.	.	.
cord-009417-458rrhcm	288	1	Granulocyte	Granulocyte	NNP
cord-009417-458rrhcm	288	2	concentrates	concentrate	VBZ
cord-009417-458rrhcm	288	3	for	for	IN
cord-009417-458rrhcm	288	4	transfusion	transfusion	NN
cord-009417-458rrhcm	288	5	are	be	VBP
cord-009417-458rrhcm	288	6	obtained	obtain	VBN
cord-009417-458rrhcm	288	7	from	from	IN
cord-009417-458rrhcm	288	8	a	a	DT
cord-009417-458rrhcm	288	9	single	single	JJ
cord-009417-458rrhcm	288	10	donor	donor	NN
cord-009417-458rrhcm	288	11	by	by	IN
cord-009417-458rrhcm	288	12	cytapheresis	cytapheresis	NN
cord-009417-458rrhcm	288	13	methods	method	NNS
cord-009417-458rrhcm	288	14	,	,	,
cord-009417-458rrhcm	288	15	which	which	WDT
cord-009417-458rrhcm	288	16	generally	generally	RB
cord-009417-458rrhcm	288	17	involve	involve	VBP
cord-009417-458rrhcm	288	18	the	the	DT
cord-009417-458rrhcm	288	19	administration	administration	NN
cord-009417-458rrhcm	288	20	of	of	IN
cord-009417-458rrhcm	288	21	hydroxyethyl	hydroxyethyl	NN
cord-009417-458rrhcm	288	22	starch	starch	NN
cord-009417-458rrhcm	288	23	and	and	CC
cord-009417-458rrhcm	288	24	corticosteroids	corticosteroid	NNS
cord-009417-458rrhcm	288	25	to	to	IN
cord-009417-458rrhcm	288	26	the	the	DT
cord-009417-458rrhcm	288	27	donor	donor	NN
cord-009417-458rrhcm	288	28	to	to	TO
cord-009417-458rrhcm	288	29	improve	improve	VB
cord-009417-458rrhcm	288	30	granulocyte	granulocyte	NN
cord-009417-458rrhcm	288	31	yield	yield	NN
cord-009417-458rrhcm	288	32	.	.	.
cord-009417-458rrhcm	289	1	Granulocyte	Granulocyte	NNP
cord-009417-458rrhcm	289	2	colony	colony	NN
cord-009417-458rrhcm	289	3	-	-	HYPH
cord-009417-458rrhcm	289	4	stimulating	stimulate	VBG
cord-009417-458rrhcm	289	5	factor	factor	NN
cord-009417-458rrhcm	289	6	(	(	-LRB-
cord-009417-458rrhcm	289	7	G	G	NNP
cord-009417-458rrhcm	289	8	-	-	HYPH
cord-009417-458rrhcm	289	9	CSF	CSF	NNP
cord-009417-458rrhcm	289	10	)	)	-RRB-
cord-009417-458rrhcm	289	11	has	have	VBZ
cord-009417-458rrhcm	289	12	been	be	VBN
cord-009417-458rrhcm	289	13	added	add	VBN
cord-009417-458rrhcm	289	14	to	to	IN
cord-009417-458rrhcm	289	15	some	some	DT
cord-009417-458rrhcm	289	16	collection	collection	NN
cord-009417-458rrhcm	289	17	regimens	regimen	NNS
cord-009417-458rrhcm	289	18	and	and	CC
cord-009417-458rrhcm	289	19	increases	increase	NNS
cord-009417-458rrhcm	289	20	both	both	DT
cord-009417-458rrhcm	289	21	cell	cell	NN
cord-009417-458rrhcm	289	22	counts	count	NNS
cord-009417-458rrhcm	289	23	and	and	CC
cord-009417-458rrhcm	289	24	granulocyte	granulocyte	NN
cord-009417-458rrhcm	289	25	survival	survival	NN
cord-009417-458rrhcm	289	26	substantially	substantially	RB
cord-009417-458rrhcm	289	27	.	.	.
cord-009417-458rrhcm	290	1	Each	each	DT
cord-009417-458rrhcm	290	2	collection	collection	NN
cord-009417-458rrhcm	290	3	should	should	MD
cord-009417-458rrhcm	290	4	contain	contain	VB
cord-009417-458rrhcm	290	5	at	at	IN
cord-009417-458rrhcm	290	6	least	least	RBS
cord-009417-458rrhcm	290	7	10	10	CD
cord-009417-458rrhcm	290	8	10	10	CD
cord-009417-458rrhcm	290	9	granulocytes	granulocyte	NNS
cord-009417-458rrhcm	290	10	1,2	1,2	CD
cord-009417-458rrhcm	290	11	and	and	CC
cord-009417-458rrhcm	290	12	is	be	VBZ
cord-009417-458rrhcm	290	13	suspended	suspend	VBN
cord-009417-458rrhcm	290	14	in	in	IN
cord-009417-458rrhcm	290	15	approximately	approximately	RB
cord-009417-458rrhcm	290	16	200	200	CD
cord-009417-458rrhcm	290	17	mL	ml	NN
cord-009417-458rrhcm	290	18	of	of	IN
cord-009417-458rrhcm	290	19	plasma	plasma	NN
cord-009417-458rrhcm	290	20	.	.	.
cord-009417-458rrhcm	291	1	A	a	DT
cord-009417-458rrhcm	291	2	signifi	signifi	NN
cord-009417-458rrhcm	291	3	ca	can	MD
cord-009417-458rrhcm	291	4	nt	not	RB
cord-009417-458rrhcm	291	5	number	number	NN
cord-009417-458rrhcm	291	6	of	of	IN
cord-009417-458rrhcm	291	7	red	red	JJ
cord-009417-458rrhcm	291	8	cells	cell	NNS
cord-009417-458rrhcm	291	9	are	be	VBP
cord-009417-458rrhcm	291	10	present	present	JJ
cord-009417-458rrhcm	291	11	,	,	,
cord-009417-458rrhcm	291	12	so	so	RB
cord-009417-458rrhcm	291	13	crossmatching	crossmatche	VBG
cord-009417-458rrhcm	291	14	for	for	IN
cord-009417-458rrhcm	291	15	the	the	DT
cord-009417-458rrhcm	291	16	recipient	recipient	NN
cord-009417-458rrhcm	291	17	is	be	VBZ
cord-009417-458rrhcm	291	18	required	require	VBN
cord-009417-458rrhcm	291	19	.	.	.
cord-009417-458rrhcm	292	1	Because	because	IN
cord-009417-458rrhcm	292	2	of	of	IN
cord-009417-458rrhcm	292	3	the	the	DT
cord-009417-458rrhcm	292	4	potential	potential	JJ
cord-009417-458rrhcm	292	5	risk	risk	NN
cord-009417-458rrhcm	292	6	for	for	IN
cord-009417-458rrhcm	292	7	graft	graft	NN
cord-009417-458rrhcm	292	8	-	-	HYPH
cord-009417-458rrhcm	292	9	versus	versus	IN
cord-009417-458rrhcm	292	10	-	-	HYPH
cord-009417-458rrhcm	292	11	host	host	NN
cord-009417-458rrhcm	292	12	disease	disease	NN
cord-009417-458rrhcm	292	13	(	(	-LRB-
cord-009417-458rrhcm	292	14	GVHD	GVHD	NNP
cord-009417-458rrhcm	292	15	)	)	-RRB-
cord-009417-458rrhcm	292	16	,	,	,
cord-009417-458rrhcm	292	17	granulocytes	granulocyte	NNS
cord-009417-458rrhcm	292	18	are	be	VBP
cord-009417-458rrhcm	292	19	usually	usually	RB
cord-009417-458rrhcm	292	20	collected	collect	VBN
cord-009417-458rrhcm	292	21	from	from	IN
cord-009417-458rrhcm	292	22	HLA	HLA	NNP
cord-009417-458rrhcm	292	23	-	-	HYPH
cord-009417-458rrhcm	292	24	matched	match	VBN
cord-009417-458rrhcm	292	25	donors	donor	NNS
cord-009417-458rrhcm	292	26	.	.	.
cord-009417-458rrhcm	293	1	Granulocytes	granulocyte	NNS
cord-009417-458rrhcm	293	2	are	be	VBP
cord-009417-458rrhcm	293	3	stored	store	VBN
cord-009417-458rrhcm	293	4	at	at	IN
cord-009417-458rrhcm	293	5	room	room	NN
cord-009417-458rrhcm	293	6	temperature	temperature	NN
cord-009417-458rrhcm	293	7	and	and	CC
cord-009417-458rrhcm	293	8	must	must	MD
cord-009417-458rrhcm	293	9	be	be	VB
cord-009417-458rrhcm	293	10	transfused	transfuse	VBN
cord-009417-458rrhcm	293	11	within	within	IN
cord-009417-458rrhcm	293	12	24	24	CD
cord-009417-458rrhcm	293	13	hours	hour	NNS
cord-009417-458rrhcm	293	14	of	of	IN
cord-009417-458rrhcm	293	15	collection	collection	NN
cord-009417-458rrhcm	293	16	,	,	,
cord-009417-458rrhcm	293	17	although	although	IN
cord-009417-458rrhcm	293	18	sooner	sooner	RB
cord-009417-458rrhcm	293	19	is	be	VBZ
cord-009417-458rrhcm	293	20	better	well	JJR
cord-009417-458rrhcm	293	21	because	because	IN
cord-009417-458rrhcm	293	22	of	of	IN
cord-009417-458rrhcm	293	23	rapid	rapid	JJ
cord-009417-458rrhcm	293	24	deterioration	deterioration	NN
cord-009417-458rrhcm	293	25	of	of	IN
cord-009417-458rrhcm	293	26	the	the	DT
cord-009417-458rrhcm	293	27	cells	cell	NNS
cord-009417-458rrhcm	293	28	.	.	.
cord-009417-458rrhcm	294	1	Patients	patient	NNS
cord-009417-458rrhcm	294	2	who	who	WP
cord-009417-458rrhcm	294	3	may	may	MD
cord-009417-458rrhcm	294	4	benefi	benefi	VB
cord-009417-458rrhcm	294	5	t	t	NN
cord-009417-458rrhcm	294	6	from	from	IN
cord-009417-458rrhcm	294	7	granulocyte	granulocyte	NN
cord-009417-458rrhcm	294	8	transfusions	transfusion	NNS
cord-009417-458rrhcm	294	9	include	include	VBP
cord-009417-458rrhcm	294	10	those	those	DT
cord-009417-458rrhcm	294	11	who	who	WP
cord-009417-458rrhcm	294	12	are	be	VBP
cord-009417-458rrhcm	294	13	neutropenic	neutropenic	JJ
cord-009417-458rrhcm	294	14	(	(	-LRB-
cord-009417-458rrhcm	294	15	absolute	absolute	JJ
cord-009417-458rrhcm	294	16	neutrophil	neutrophil	NN
cord-009417-458rrhcm	294	17	count	count	NN
cord-009417-458rrhcm	294	18	of	of	IN
cord-009417-458rrhcm	294	19	less	less	JJR
cord-009417-458rrhcm	294	20	than	than	IN
cord-009417-458rrhcm	294	21	0.5	0.5	CD
cord-009417-458rrhcm	294	22	×	×	CD
cord-009417-458rrhcm	294	23	10	10	CD
cord-009417-458rrhcm	294	24	9	9	CD
cord-009417-458rrhcm	294	25	/L	/L	.
cord-009417-458rrhcm	294	26	)	)	-RRB-
cord-009417-458rrhcm	294	27	and	and	CC
cord-009417-458rrhcm	294	28	those	those	DT
cord-009417-458rrhcm	294	29	who	who	WP
cord-009417-458rrhcm	294	30	are	be	VBP
cord-009417-458rrhcm	294	31	unresponsive	unresponsive	JJ
cord-009417-458rrhcm	294	32	to	to	TO
cord-009417-458rrhcm	294	33	appropriate	appropriate	VB
cord-009417-458rrhcm	294	34	antibiotic	antibiotic	JJ
cord-009417-458rrhcm	294	35	treatment	treatment	NN
cord-009417-458rrhcm	294	36	but	but	CC
cord-009417-458rrhcm	294	37	in	in	IN
cord-009417-458rrhcm	294	38	whom	whom	WP
cord-009417-458rrhcm	294	39	bone	bone	NN
cord-009417-458rrhcm	294	40	marrow	marrow	NN
cord-009417-458rrhcm	294	41	recovery	recovery	NN
cord-009417-458rrhcm	294	42	is	be	VBZ
cord-009417-458rrhcm	294	43	expected	expect	VBN
cord-009417-458rrhcm	294	44	to	to	TO
cord-009417-458rrhcm	294	45	occur	occur	VB
cord-009417-458rrhcm	294	46	.	.	.
cord-009417-458rrhcm	295	1	A	a	DT
cord-009417-458rrhcm	295	2	course	course	NN
cord-009417-458rrhcm	295	3	of	of	IN
cord-009417-458rrhcm	295	4	therapy	therapy	NN
cord-009417-458rrhcm	295	5	generally	generally	RB
cord-009417-458rrhcm	295	6	involves	involve	VBZ
cord-009417-458rrhcm	295	7	daily	daily	JJ
cord-009417-458rrhcm	295	8	infusion	infusion	NN
cord-009417-458rrhcm	295	9	for	for	IN
cord-009417-458rrhcm	295	10	4	4	CD
cord-009417-458rrhcm	295	11	to	to	TO
cord-009417-458rrhcm	295	12	7	7	CD
cord-009417-458rrhcm	295	13	days	day	NNS
cord-009417-458rrhcm	295	14	.	.	.
cord-009417-458rrhcm	296	1	Granulocytes	granulocyte	NNS
cord-009417-458rrhcm	296	2	have	have	VBP
cord-009417-458rrhcm	296	3	been	be	VBN
cord-009417-458rrhcm	296	4	used	use	VBN
cord-009417-458rrhcm	296	5	for	for	IN
cord-009417-458rrhcm	296	6	progressive	progressive	JJ
cord-009417-458rrhcm	296	7	fungal	fungal	JJ
cord-009417-458rrhcm	296	8	infections	infection	NNS
cord-009417-458rrhcm	296	9	in	in	IN
cord-009417-458rrhcm	296	10	immunosuppressed	immunosuppressed	JJ
cord-009417-458rrhcm	296	11	granulocytopenic	granulocytopenic	NN
cord-009417-458rrhcm	296	12	patients	patient	NNS
cord-009417-458rrhcm	296	13	,	,	,
cord-009417-458rrhcm	296	14	in	in	IN
cord-009417-458rrhcm	296	15	patients	patient	NNS
cord-009417-458rrhcm	296	16	with	with	IN
cord-009417-458rrhcm	296	17	defective	defective	JJ
cord-009417-458rrhcm	296	18	leukocytes	leukocyte	NNS
cord-009417-458rrhcm	296	19	(	(	-LRB-
cord-009417-458rrhcm	296	20	e.g.	e.g.	RB
cord-009417-458rrhcm	296	21	,	,	,
cord-009417-458rrhcm	296	22	chronic	chronic	JJ
cord-009417-458rrhcm	296	23	granulomatous	granulomatous	JJ
cord-009417-458rrhcm	296	24	disease	disease	NN
cord-009417-458rrhcm	296	25	)	)	-RRB-
cord-009417-458rrhcm	296	26	,	,	,
cord-009417-458rrhcm	296	27	and	and	CC
cord-009417-458rrhcm	296	28	in	in	IN
cord-009417-458rrhcm	296	29	the	the	DT
cord-009417-458rrhcm	296	30	neonatal	neonatal	JJ
cord-009417-458rrhcm	296	31	ICU	ICU	NNP
cord-009417-458rrhcm	296	32	for	for	IN
cord-009417-458rrhcm	296	33	neonatal	neonatal	JJ
cord-009417-458rrhcm	296	34	sepsis	sepsis	NN
cord-009417-458rrhcm	296	35	.	.	.
cord-009417-458rrhcm	297	1	Randomized	randomized	JJ
cord-009417-458rrhcm	297	2	trials	trial	NNS
cord-009417-458rrhcm	297	3	had	have	VBD
cord-009417-458rrhcm	297	4	suggested	suggest	VBN
cord-009417-458rrhcm	297	5	that	that	IN
cord-009417-458rrhcm	297	6	granulocyte	granulocyte	NN
cord-009417-458rrhcm	297	7	transfusions	transfusion	NNS
cord-009417-458rrhcm	297	8	under	under	IN
cord-009417-458rrhcm	297	9	these	these	DT
cord-009417-458rrhcm	297	10	circumstances	circumstance	NNS
cord-009417-458rrhcm	297	11	can	can	MD
cord-009417-458rrhcm	297	12	reduce	reduce	VB
cord-009417-458rrhcm	297	13	mortality	mortality	NN
cord-009417-458rrhcm	297	14	,	,	,
cord-009417-458rrhcm	297	15	but	but	CC
cord-009417-458rrhcm	297	16	such	such	JJ
cord-009417-458rrhcm	297	17	trials	trial	NNS
cord-009417-458rrhcm	297	18	have	have	VBP
cord-009417-458rrhcm	297	19	not	not	RB
cord-009417-458rrhcm	297	20	been	be	VBN
cord-009417-458rrhcm	297	21	conducted	conduct	VBN
cord-009417-458rrhcm	297	22	for	for	IN
cord-009417-458rrhcm	297	23	more	more	JJR
cord-009417-458rrhcm	297	24	than	than	IN
cord-009417-458rrhcm	297	25	2	2	CD
cord-009417-458rrhcm	297	26	decades	decade	NNS
cord-009417-458rrhcm	297	27	.	.	.
cord-009417-458rrhcm	298	1	66	66	CD
cord-009417-458rrhcm	298	2	Effective	effective	JJ
cord-009417-458rrhcm	298	3	antibiotic	antibiotic	JJ
cord-009417-458rrhcm	298	4	regimens	regimen	NNS
cord-009417-458rrhcm	298	5	and	and	CC
cord-009417-458rrhcm	298	6	the	the	DT
cord-009417-458rrhcm	298	7	signifi	signifi	NNP
cord-009417-458rrhcm	298	8	ca	can	MD
cord-009417-458rrhcm	298	9	nt	not	RB
cord-009417-458rrhcm	299	1	adverse	adverse	JJ
cord-009417-458rrhcm	299	2	effects	effect	NNS
cord-009417-458rrhcm	299	3	associated	associate	VBN
cord-009417-458rrhcm	299	4	with	with	IN
cord-009417-458rrhcm	299	5	the	the	DT
cord-009417-458rrhcm	299	6	use	use	NN
cord-009417-458rrhcm	299	7	of	of	IN
cord-009417-458rrhcm	299	8	granulocyte	granulocyte	NN
cord-009417-458rrhcm	299	9	concentrates	concentrate	VBZ
cord-009417-458rrhcm	299	10	,	,	,
cord-009417-458rrhcm	299	11	including	include	VBG
cord-009417-458rrhcm	299	12	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	299	13	insuffi	insuffi	NN
cord-009417-458rrhcm	299	14	ciency	ciency	NN
cord-009417-458rrhcm	299	15	related	relate	VBN
cord-009417-458rrhcm	299	16	to	to	IN
cord-009417-458rrhcm	299	17	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	299	18	and	and	CC
cord-009417-458rrhcm	299	19	CMV	CMV	NNP
cord-009417-458rrhcm	299	20	infection	infection	NN
cord-009417-458rrhcm	299	21	,	,	,
cord-009417-458rrhcm	299	22	have	have	VBP
cord-009417-458rrhcm	299	23	limited	limit	VBN
cord-009417-458rrhcm	299	24	their	-PRON-	PRP$
cord-009417-458rrhcm	299	25	use	use	NN
cord-009417-458rrhcm	299	26	in	in	IN
cord-009417-458rrhcm	299	27	recent	recent	JJ
cord-009417-458rrhcm	299	28	years	year	NNS
cord-009417-458rrhcm	299	29	.	.	.
cord-009417-458rrhcm	300	1	The	the	DT
cord-009417-458rrhcm	300	2	decision	decision	NN
cord-009417-458rrhcm	300	3	to	to	TO
cord-009417-458rrhcm	300	4	transfuse	transfuse	VB
cord-009417-458rrhcm	300	5	blood	blood	NN
cord-009417-458rrhcm	300	6	components	component	NNS
cord-009417-458rrhcm	300	7	,	,	,
cord-009417-458rrhcm	300	8	like	like	IN
cord-009417-458rrhcm	300	9	any	any	DT
cord-009417-458rrhcm	300	10	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	300	11	maneuver	maneuver	NN
cord-009417-458rrhcm	300	12	,	,	,
cord-009417-458rrhcm	300	13	must	must	MD
cord-009417-458rrhcm	300	14	be	be	VB
cord-009417-458rrhcm	300	15	made	make	VBN
cord-009417-458rrhcm	300	16	with	with	IN
cord-009417-458rrhcm	300	17	full	full	JJ
cord-009417-458rrhcm	300	18	awareness	awareness	NN
cord-009417-458rrhcm	300	19	of	of	IN
cord-009417-458rrhcm	300	20	the	the	DT
cord-009417-458rrhcm	300	21	potential	potential	JJ
cord-009417-458rrhcm	300	22	risk	risk	NN
cord-009417-458rrhcm	300	23	to	to	IN
cord-009417-458rrhcm	300	24	the	the	DT
cord-009417-458rrhcm	300	25	recipient	recipient	NN
cord-009417-458rrhcm	300	26	,	,	,
cord-009417-458rrhcm	300	27	as	as	RB
cord-009417-458rrhcm	300	28	well	well	RB
cord-009417-458rrhcm	300	29	as	as	IN
cord-009417-458rrhcm	300	30	the	the	DT
cord-009417-458rrhcm	300	31	expected	expect	VBN
cord-009417-458rrhcm	300	32	benefi	benefi	NNP
cord-009417-458rrhcm	300	33	ts	ts	NNP
cord-009417-458rrhcm	300	34	.	.	.
cord-009417-458rrhcm	301	1	Public	public	JJ
cord-009417-458rrhcm	301	2	expectations	expectation	NNS
cord-009417-458rrhcm	301	3	of	of	IN
cord-009417-458rrhcm	301	4	a	a	DT
cord-009417-458rrhcm	301	5	zero	zero	CD
cord-009417-458rrhcm	301	6	-	-	HYPH
cord-009417-458rrhcm	301	7	risk	risk	NN
cord-009417-458rrhcm	301	8	blood	blood	NN
cord-009417-458rrhcm	301	9	supply	supply	NN
cord-009417-458rrhcm	301	10	help	help	NN
cord-009417-458rrhcm	301	11	raise	raise	VB
cord-009417-458rrhcm	301	12	the	the	DT
cord-009417-458rrhcm	301	13	acuity	acuity	NN
cord-009417-458rrhcm	301	14	of	of	IN
cord-009417-458rrhcm	301	15	physicians	physician	NNS
cord-009417-458rrhcm	301	16	'	'	POS
cord-009417-458rrhcm	301	17	decisions	decision	NNS
cord-009417-458rrhcm	301	18	.	.	.
cord-009417-458rrhcm	302	1	For	for	IN
cord-009417-458rrhcm	302	2	some	some	DT
cord-009417-458rrhcm	302	3	patients	patient	NNS
cord-009417-458rrhcm	302	4	,	,	,
cord-009417-458rrhcm	302	5	the	the	DT
cord-009417-458rrhcm	302	6	benefi	benefi	NNP
cord-009417-458rrhcm	302	7	t	t	NN
cord-009417-458rrhcm	302	8	from	from	IN
cord-009417-458rrhcm	302	9	transfusion	transfusion	NN
cord-009417-458rrhcm	302	10	is	be	VBZ
cord-009417-458rrhcm	302	11	so	so	RB
cord-009417-458rrhcm	302	12	obvious	obvious	JJ
cord-009417-458rrhcm	302	13	that	that	IN
cord-009417-458rrhcm	302	14	the	the	DT
cord-009417-458rrhcm	302	15	associated	associate	VBN
cord-009417-458rrhcm	302	16	risks	risk	NNS
cord-009417-458rrhcm	302	17	pale	pale	JJ
cord-009417-458rrhcm	302	18	in	in	IN
cord-009417-458rrhcm	302	19	comparison	comparison	NN
cord-009417-458rrhcm	302	20	to	to	IN
cord-009417-458rrhcm	302	21	the	the	DT
cord-009417-458rrhcm	302	22	consequences	consequence	NNS
cord-009417-458rrhcm	302	23	of	of	IN
cord-009417-458rrhcm	302	24	withholding	withhold	VBG
cord-009417-458rrhcm	302	25	transfusion	transfusion	NN
cord-009417-458rrhcm	302	26	.	.	.
cord-009417-458rrhcm	303	1	However	however	RB
cord-009417-458rrhcm	303	2	,	,	,
cord-009417-458rrhcm	303	3	the	the	DT
cord-009417-458rrhcm	303	4	clinician	clinician	NN
cord-009417-458rrhcm	303	5	's	's	POS
cord-009417-458rrhcm	303	6	knowledge	knowledge	NN
cord-009417-458rrhcm	303	7	of	of	IN
cord-009417-458rrhcm	303	8	the	the	DT
cord-009417-458rrhcm	303	9	incidence	incidence	NN
cord-009417-458rrhcm	303	10	and	and	CC
cord-009417-458rrhcm	303	11	management	management	NN
cord-009417-458rrhcm	303	12	of	of	IN
cord-009417-458rrhcm	303	13	adverse	adverse	JJ
cord-009417-458rrhcm	303	14	reactions	reaction	NNS
cord-009417-458rrhcm	303	15	to	to	IN
cord-009417-458rrhcm	303	16	transfusion	transfusion	NN
cord-009417-458rrhcm	303	17	is	be	VBZ
cord-009417-458rrhcm	303	18	vital	vital	JJ
cord-009417-458rrhcm	303	19	,	,	,
cord-009417-458rrhcm	303	20	not	not	RB
cord-009417-458rrhcm	303	21	only	only	RB
cord-009417-458rrhcm	303	22	to	to	TO
cord-009417-458rrhcm	303	23	ensure	ensure	VB
cord-009417-458rrhcm	303	24	the	the	DT
cord-009417-458rrhcm	303	25	best	good	JJS
cord-009417-458rrhcm	303	26	patient	patient	JJ
cord-009417-458rrhcm	303	27	care	care	NN
cord-009417-458rrhcm	303	28	but	but	CC
cord-009417-458rrhcm	303	29	also	also	RB
cord-009417-458rrhcm	303	30	to	to	TO
cord-009417-458rrhcm	303	31	provide	provide	VB
cord-009417-458rrhcm	303	32	appropriate	appropriate	JJ
cord-009417-458rrhcm	303	33	patient	patient	JJ
cord-009417-458rrhcm	303	34	education	education	NN
cord-009417-458rrhcm	303	35	and	and	CC
cord-009417-458rrhcm	303	36	true	true	JJ
cord-009417-458rrhcm	303	37	informed	informed	JJ
cord-009417-458rrhcm	303	38	consent	consent	NN
cord-009417-458rrhcm	303	39	.	.	.
cord-009417-458rrhcm	304	1	Almost	almost	RB
cord-009417-458rrhcm	304	2	every	every	DT
cord-009417-458rrhcm	304	3	patient	patient	NN
cord-009417-458rrhcm	304	4	who	who	WP
cord-009417-458rrhcm	304	5	receives	receive	VBZ
cord-009417-458rrhcm	304	6	an	an	DT
cord-009417-458rrhcm	304	7	allogeneic	allogeneic	NN
cord-009417-458rrhcm	304	8	blood	blood	NN
cord-009417-458rrhcm	304	9	transfusion	transfusion	NN
cord-009417-458rrhcm	304	10	will	will	MD
cord-009417-458rrhcm	304	11	experience	experience	VB
cord-009417-458rrhcm	304	12	some	some	DT
cord-009417-458rrhcm	304	13	adverse	adverse	JJ
cord-009417-458rrhcm	304	14	reaction	reaction	NN
cord-009417-458rrhcm	304	15	if	if	IN
cord-009417-458rrhcm	304	16	such	such	JJ
cord-009417-458rrhcm	304	17	universal	universal	JJ
cord-009417-458rrhcm	304	18	effects	effect	NNS
cord-009417-458rrhcm	304	19	as	as	IN
cord-009417-458rrhcm	304	20	immunomodulation	immunomodulation	NN
cord-009417-458rrhcm	304	21	and	and	CC
cord-009417-458rrhcm	304	22	bone	bone	NN
cord-009417-458rrhcm	304	23	marrow	marrow	NN
cord-009417-458rrhcm	304	24	suppression	suppression	NN
cord-009417-458rrhcm	304	25	are	be	VBP
cord-009417-458rrhcm	304	26	considered	consider	VBN
cord-009417-458rrhcm	304	27	.	.	.
cord-009417-458rrhcm	305	1	Measurable	measurable	JJ
cord-009417-458rrhcm	305	2	reactions	reaction	NNS
cord-009417-458rrhcm	305	3	to	to	IN
cord-009417-458rrhcm	305	4	transfusion	transfusion	NN
cord-009417-458rrhcm	305	5	occur	occur	VBP
cord-009417-458rrhcm	305	6	in	in	IN
cord-009417-458rrhcm	305	7	about	about	RB
cord-009417-458rrhcm	305	8	20	20	CD
cord-009417-458rrhcm	305	9	%	%	NN
cord-009417-458rrhcm	305	10	of	of	IN
cord-009417-458rrhcm	305	11	patients	patient	NNS
cord-009417-458rrhcm	305	12	;	;	:
cord-009417-458rrhcm	305	13	more	more	RBR
cord-009417-458rrhcm	305	14	serious	serious	JJ
cord-009417-458rrhcm	305	15	adverse	adverse	JJ
cord-009417-458rrhcm	305	16	responses	response	NNS
cord-009417-458rrhcm	305	17	may	may	MD
cord-009417-458rrhcm	305	18	be	be	VB
cord-009417-458rrhcm	305	19	expected	expect	VBN
cord-009417-458rrhcm	305	20	in	in	IN
cord-009417-458rrhcm	305	21	only	only	RB
cord-009417-458rrhcm	305	22	1	1	CD
cord-009417-458rrhcm	305	23	%	%	NN
cord-009417-458rrhcm	305	24	to	to	TO
cord-009417-458rrhcm	305	25	2	2	CD
cord-009417-458rrhcm	305	26	%	%	NN
cord-009417-458rrhcm	305	27	of	of	IN
cord-009417-458rrhcm	305	28	transfusions	transfusion	NNS
cord-009417-458rrhcm	305	29	.	.	.
cord-009417-458rrhcm	306	1	67	67	CD
cord-009417-458rrhcm	307	1	The	the	DT
cord-009417-458rrhcm	307	2	nature	nature	NN
cord-009417-458rrhcm	307	3	of	of	IN
cord-009417-458rrhcm	307	4	these	these	DT
cord-009417-458rrhcm	307	5	adverse	adverse	JJ
cord-009417-458rrhcm	307	6	reactions	reaction	NNS
cord-009417-458rrhcm	307	7	ranges	range	VBZ
cord-009417-458rrhcm	307	8	from	from	IN
cord-009417-458rrhcm	307	9	those	those	DT
cord-009417-458rrhcm	307	10	that	that	WDT
cord-009417-458rrhcm	307	11	are	be	VBP
cord-009417-458rrhcm	307	12	common	common	JJ
cord-009417-458rrhcm	307	13	but	but	CC
cord-009417-458rrhcm	307	14	clinically	clinically	RB
cord-009417-458rrhcm	307	15	unimportant	unimportant	JJ
cord-009417-458rrhcm	307	16	to	to	IN
cord-009417-458rrhcm	307	17	those	those	DT
cord-009417-458rrhcm	307	18	that	that	WDT
cord-009417-458rrhcm	307	19	may	may	MD
cord-009417-458rrhcm	307	20	cause	cause	VB
cord-009417-458rrhcm	307	21	signifi	signifi	NNP
cord-009417-458rrhcm	307	22	ca	can	MD
cord-009417-458rrhcm	307	23	nt	not	RB
cord-009417-458rrhcm	307	24	morbidity	morbidity	NN
cord-009417-458rrhcm	307	25	or	or	CC
cord-009417-458rrhcm	307	26	death	death	NN
cord-009417-458rrhcm	307	27	(	(	-LRB-
cord-009417-458rrhcm	307	28	Table	Table	NNP
cord-009417-458rrhcm	307	29	80	80	CD
cord-009417-458rrhcm	307	30	-	-	SYM
cord-009417-458rrhcm	307	31	3	3	CD
cord-009417-458rrhcm	307	32	)	)	-RRB-
cord-009417-458rrhcm	307	33	.	.	.
cord-009417-458rrhcm	308	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	308	2	in	in	IN
cord-009417-458rrhcm	308	3	the	the	DT
cord-009417-458rrhcm	308	4	ICU	ICU	NNP
cord-009417-458rrhcm	308	5	is	be	VBZ
cord-009417-458rrhcm	308	6	a	a	DT
cord-009417-458rrhcm	308	7	common	common	JJ
cord-009417-458rrhcm	308	8	and	and	CC
cord-009417-458rrhcm	308	9	often	often	RB
cord-009417-458rrhcm	308	10	lightly	lightly	RB
cord-009417-458rrhcm	308	11	regarded	regard	VBN
cord-009417-458rrhcm	308	12	event	event	NN
cord-009417-458rrhcm	308	13	.	.	.
cord-009417-458rrhcm	309	1	However	however	RB
cord-009417-458rrhcm	309	2	,	,	,
cord-009417-458rrhcm	309	3	because	because	IN
cord-009417-458rrhcm	309	4	the	the	DT
cord-009417-458rrhcm	309	5	signs	sign	NNS
cord-009417-458rrhcm	309	6	and	and	CC
cord-009417-458rrhcm	309	7	symptoms	symptom	NNS
cord-009417-458rrhcm	309	8	of	of	IN
cord-009417-458rrhcm	309	9	severe	severe	JJ
cord-009417-458rrhcm	309	10	,	,	,
cord-009417-458rrhcm	309	11	life	life	NN
cord-009417-458rrhcm	309	12	-	-	HYPH
cord-009417-458rrhcm	309	13	threatening	threaten	VBG
cord-009417-458rrhcm	309	14	reactions	reaction	NNS
cord-009417-458rrhcm	309	15	are	be	VBP
cord-009417-458rrhcm	309	16	frequently	frequently	RB
cord-009417-458rrhcm	309	17	indistinguishable	indistinguishable	JJ
cord-009417-458rrhcm	309	18	from	from	IN
cord-009417-458rrhcm	309	19	those	those	DT
cord-009417-458rrhcm	309	20	of	of	IN
cord-009417-458rrhcm	309	21	troublesome	troublesome	JJ
cord-009417-458rrhcm	309	22	,	,	,
cord-009417-458rrhcm	309	23	but	but	CC
cord-009417-458rrhcm	309	24	less	less	JJR
cord-009417-458rrhcm	309	25	signifi	signifi	NNP
cord-009417-458rrhcm	309	26	ca	can	MD
cord-009417-458rrhcm	309	27	nt	not	RB
cord-009417-458rrhcm	309	28	reactions	reaction	NNS
cord-009417-458rrhcm	309	29	,	,	.
cord-009417-458rrhcm	310	1	every	every	DT
cord-009417-458rrhcm	310	2	transfused	transfuse	VBN
cord-009417-458rrhcm	310	3	patient	patient	NN
cord-009417-458rrhcm	310	4	who	who	WP
cord-009417-458rrhcm	310	5	experiences	experience	VBZ
cord-009417-458rrhcm	310	6	a	a	DT
cord-009417-458rrhcm	310	7	signifi	signifi	NN
cord-009417-458rrhcm	310	8	ca	can	MD
cord-009417-458rrhcm	310	9	nt	not	RB
cord-009417-458rrhcm	310	10	change	change	VB
cord-009417-458rrhcm	310	11	in	in	IN
cord-009417-458rrhcm	310	12	condition	condition	NN
cord-009417-458rrhcm	310	13	,	,	,
cord-009417-458rrhcm	310	14	such	such	JJ
cord-009417-458rrhcm	310	15	as	as	IN
cord-009417-458rrhcm	310	16	an	an	DT
cord-009417-458rrhcm	310	17	elevation	elevation	NN
cord-009417-458rrhcm	310	18	in	in	IN
cord-009417-458rrhcm	310	19	temperature	temperature	NN
cord-009417-458rrhcm	310	20	,	,	,
cord-009417-458rrhcm	310	21	change	change	NN
cord-009417-458rrhcm	310	22	in	in	IN
cord-009417-458rrhcm	310	23	pulse	pulse	NN
cord-009417-458rrhcm	310	24	or	or	CC
cord-009417-458rrhcm	310	25	blood	blood	NN
cord-009417-458rrhcm	310	26	pressure	pressure	NN
cord-009417-458rrhcm	310	27	,	,	,
cord-009417-458rrhcm	310	28	dyspnea	dyspnea	NN
cord-009417-458rrhcm	310	29	,	,	,
cord-009417-458rrhcm	310	30	or	or	CC
cord-009417-458rrhcm	310	31	pain	pain	NN
cord-009417-458rrhcm	310	32	,	,	,
cord-009417-458rrhcm	310	33	must	must	MD
cord-009417-458rrhcm	310	34	be	be	VB
cord-009417-458rrhcm	310	35	promptly	promptly	RB
cord-009417-458rrhcm	310	36	and	and	CC
cord-009417-458rrhcm	310	37	fully	fully	RB
cord-009417-458rrhcm	310	38	evaluated	evaluate	VBN
cord-009417-458rrhcm	310	39	to	to	TO
cord-009417-458rrhcm	310	40	identify	identify	VB
cord-009417-458rrhcm	310	41	the	the	DT
cord-009417-458rrhcm	310	42	cause	cause	NN
cord-009417-458rrhcm	310	43	of	of	IN
cord-009417-458rrhcm	310	44	the	the	DT
cord-009417-458rrhcm	310	45	reaction	reaction	NN
cord-009417-458rrhcm	310	46	and	and	CC
cord-009417-458rrhcm	310	47	to	to	IN
cord-009417-458rrhcm	310	48	institute	institute	VB
cord-009417-458rrhcm	310	49	treatment	treatment	NN
cord-009417-458rrhcm	310	50	when	when	WRB
cord-009417-458rrhcm	310	51	necessary	necessary	JJ
cord-009417-458rrhcm	310	52	.	.	.
cord-009417-458rrhcm	311	1	The	the	DT
cord-009417-458rrhcm	311	2	basic	basic	JJ
cord-009417-458rrhcm	311	3	approach	approach	NN
cord-009417-458rrhcm	311	4	to	to	IN
cord-009417-458rrhcm	311	5	all	all	DT
cord-009417-458rrhcm	311	6	acute	acute	JJ
cord-009417-458rrhcm	311	7	reactions	reaction	NNS
cord-009417-458rrhcm	311	8	should	should	MD
cord-009417-458rrhcm	311	9	be	be	VB
cord-009417-458rrhcm	311	10	to	to	TO
cord-009417-458rrhcm	311	11	maintain	maintain	VB
cord-009417-458rrhcm	311	12	a	a	DT
cord-009417-458rrhcm	311	13	high	high	JJ
cord-009417-458rrhcm	311	14	index	index	NN
cord-009417-458rrhcm	311	15	of	of	IN
cord-009417-458rrhcm	311	16	suspicion	suspicion	NN
cord-009417-458rrhcm	311	17	for	for	IN
cord-009417-458rrhcm	311	18	acute	acute	JJ
cord-009417-458rrhcm	311	19	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	311	20	reactions	reaction	NNS
cord-009417-458rrhcm	311	21	by	by	IN
cord-009417-458rrhcm	311	22	stopping	stop	VBG
cord-009417-458rrhcm	311	23	the	the	DT
cord-009417-458rrhcm	311	24	transfusion	transfusion	NN
cord-009417-458rrhcm	311	25	immediately	immediately	RB
cord-009417-458rrhcm	311	26	,	,	,
cord-009417-458rrhcm	311	27	maintaining	maintain	VBG
cord-009417-458rrhcm	311	28	venous	venous	JJ
cord-009417-458rrhcm	311	29	access	access	NN
cord-009417-458rrhcm	311	30	with	with	IN
cord-009417-458rrhcm	311	31	intravenous	intravenous	JJ
cord-009417-458rrhcm	311	32	fl	fl	NNP
cord-009417-458rrhcm	311	33	uids	uid	NNS
cord-009417-458rrhcm	311	34	,	,	,
cord-009417-458rrhcm	311	35	and	and	CC
cord-009417-458rrhcm	311	36	informing	inform	VBG
cord-009417-458rrhcm	311	37	the	the	DT
cord-009417-458rrhcm	311	38	blood	blood	NN
cord-009417-458rrhcm	311	39	bank	bank	NN
cord-009417-458rrhcm	311	40	laboratory	laboratory	NN
cord-009417-458rrhcm	311	41	immediately	immediately	RB
cord-009417-458rrhcm	311	42	so	so	IN
cord-009417-458rrhcm	311	43	that	that	IN
cord-009417-458rrhcm	311	44	the	the	DT
cord-009417-458rrhcm	311	45	appropriate	appropriate	JJ
cord-009417-458rrhcm	311	46	transfusion	transfusion	NN
cord-009417-458rrhcm	311	47	reaction	reaction	NN
cord-009417-458rrhcm	311	48	protocol	protocol	NN
cord-009417-458rrhcm	311	49	can	can	MD
cord-009417-458rrhcm	311	50	be	be	VB
cord-009417-458rrhcm	311	51	in	in	IN
cord-009417-458rrhcm	311	52	stituted	stituted	JJ
cord-009417-458rrhcm	311	53	and	and	CC
cord-009417-458rrhcm	311	54	post	post	JJ
cord-009417-458rrhcm	311	55	-	-	JJ
cord-009417-458rrhcm	311	56	transfusion	transfusion	NN
cord-009417-458rrhcm	311	57	specimens	specimen	NNS
cord-009417-458rrhcm	311	58	obtained	obtain	VBN
cord-009417-458rrhcm	311	59	.	.	.
cord-009417-458rrhcm	312	1	Early	early	JJ
cord-009417-458rrhcm	312	2	recognition	recognition	NN
cord-009417-458rrhcm	312	3	of	of	IN
cord-009417-458rrhcm	312	4	severe	severe	JJ
cord-009417-458rrhcm	312	5	transfusion	transfusion	NN
cord-009417-458rrhcm	312	6	reactions	reaction	NNS
cord-009417-458rrhcm	312	7	may	may	MD
cord-009417-458rrhcm	312	8	be	be	VB
cord-009417-458rrhcm	312	9	lifesaving	lifesave	VBG
cord-009417-458rrhcm	312	10	.	.	.
cord-009417-458rrhcm	313	1	The	the	DT
cord-009417-458rrhcm	313	2	most	most	RBS
cord-009417-458rrhcm	313	3	feared	fear	VBN
cord-009417-458rrhcm	313	4	reaction	reaction	NN
cord-009417-458rrhcm	313	5	to	to	IN
cord-009417-458rrhcm	313	6	blood	blood	NN
cord-009417-458rrhcm	313	7	transfusion	transfusion	NN
cord-009417-458rrhcm	313	8	is	be	VBZ
cord-009417-458rrhcm	313	9	intravascular	intravascular	JJ
cord-009417-458rrhcm	313	10	hemolysis	hemolysis	NN
cord-009417-458rrhcm	313	11	,	,	,
cord-009417-458rrhcm	313	12	caused	cause	VBN
cord-009417-458rrhcm	313	13	by	by	IN
cord-009417-458rrhcm	313	14	the	the	DT
cord-009417-458rrhcm	313	15	recipient	recipient	NN
cord-009417-458rrhcm	313	16	's	's	POS
cord-009417-458rrhcm	313	17	complementfi	complementfi	NNP
cord-009417-458rrhcm	313	18	xing	xing	NNP
cord-009417-458rrhcm	313	19	antibodies	antibody	NNS
cord-009417-458rrhcm	313	20	attaching	attach	VBG
cord-009417-458rrhcm	313	21	to	to	IN
cord-009417-458rrhcm	313	22	donor	donor	NN
cord-009417-458rrhcm	313	23	RBCs	rbc	NNS
cord-009417-458rrhcm	313	24	with	with	IN
cord-009417-458rrhcm	313	25	resultant	resultant	JJ
cord-009417-458rrhcm	313	26	RBC	RBC	NNP
cord-009417-458rrhcm	313	27	lysis	lysis	NN
cord-009417-458rrhcm	313	28	.	.	.
cord-009417-458rrhcm	314	1	ABO	ABO	NNP
cord-009417-458rrhcm	314	2	incompatibility	incompatibility	NN
cord-009417-458rrhcm	314	3	is	be	VBZ
cord-009417-458rrhcm	314	4	most	most	RBS
cord-009417-458rrhcm	314	5	often	often	RB
cord-009417-458rrhcm	314	6	implicated	implicate	VBN
cord-009417-458rrhcm	314	7	in	in	IN
cord-009417-458rrhcm	314	8	these	these	DT
cord-009417-458rrhcm	314	9	incidents	incident	NNS
cord-009417-458rrhcm	314	10	.	.	.
cord-009417-458rrhcm	315	1	Intravascular	Intravascular	NNP
cord-009417-458rrhcm	315	2	hemolysis	hemolysis	NN
cord-009417-458rrhcm	315	3	is	be	VBZ
cord-009417-458rrhcm	315	4	still	still	RB
cord-009417-458rrhcm	315	5	the	the	DT
cord-009417-458rrhcm	315	6	single	single	JJ
cord-009417-458rrhcm	315	7	most	most	RBS
cord-009417-458rrhcm	315	8	common	common	JJ
cord-009417-458rrhcm	315	9	acute	acute	JJ
cord-009417-458rrhcm	315	10	cause	cause	NN
cord-009417-458rrhcm	315	11	of	of	IN
cord-009417-458rrhcm	315	12	fatalities	fatality	NNS
cord-009417-458rrhcm	315	13	associated	associate	VBN
cord-009417-458rrhcm	315	14	with	with	IN
cord-009417-458rrhcm	315	15	the	the	DT
cord-009417-458rrhcm	315	16	transfusion	transfusion	NN
cord-009417-458rrhcm	315	17	episode	episode	NN
cord-009417-458rrhcm	315	18	.	.	.
cord-009417-458rrhcm	316	1	68	68	CD
cord-009417-458rrhcm	317	1	In	in	IN
cord-009417-458rrhcm	317	2	addition	addition	NN
cord-009417-458rrhcm	317	3	to	to	IN
cord-009417-458rrhcm	317	4	hemolysis	hemolysis	NN
cord-009417-458rrhcm	317	5	,	,	,
cord-009417-458rrhcm	317	6	complement	complement	NN
cord-009417-458rrhcm	317	7	activation	activation	NN
cord-009417-458rrhcm	317	8	stimulates	stimulate	VBZ
cord-009417-458rrhcm	317	9	the	the	DT
cord-009417-458rrhcm	317	10	release	release	NN
cord-009417-458rrhcm	317	11	of	of	IN
cord-009417-458rrhcm	317	12	infl	infl	NNP
cord-009417-458rrhcm	317	13	ammatory	ammatory	NNP
cord-009417-458rrhcm	317	14	mediators	mediator	NNS
cord-009417-458rrhcm	317	15	and	and	CC
cord-009417-458rrhcm	317	16	cytokines	cytokine	NNS
cord-009417-458rrhcm	317	17	and	and	CC
cord-009417-458rrhcm	317	18	thereby	thereby	RB
cord-009417-458rrhcm	317	19	leads	lead	VBZ
cord-009417-458rrhcm	317	20	to	to	IN
cord-009417-458rrhcm	317	21	hypotension	hypotension	NN
cord-009417-458rrhcm	317	22	and	and	CC
cord-009417-458rrhcm	317	23	vascular	vascular	JJ
cord-009417-458rrhcm	317	24	collapse	collapse	NN
cord-009417-458rrhcm	317	25	.	.	.
cord-009417-458rrhcm	318	1	Activation	activation	NN
cord-009417-458rrhcm	318	2	of	of	IN
cord-009417-458rrhcm	318	3	the	the	DT
cord-009417-458rrhcm	318	4	coagulation	coagulation	NN
cord-009417-458rrhcm	318	5	system	system	NN
cord-009417-458rrhcm	318	6	may	may	MD
cord-009417-458rrhcm	318	7	result	result	VB
cord-009417-458rrhcm	318	8	in	in	IN
cord-009417-458rrhcm	318	9	DIC	DIC	NNP
cord-009417-458rrhcm	318	10	.	.	.
cord-009417-458rrhcm	319	1	Acute	acute	JJ
cord-009417-458rrhcm	319	2	renal	renal	JJ
cord-009417-458rrhcm	319	3	failure	failure	NN
cord-009417-458rrhcm	319	4	may	may	MD
cord-009417-458rrhcm	319	5	also	also	RB
cord-009417-458rrhcm	319	6	occur	occur	VB
cord-009417-458rrhcm	319	7	,	,	,
cord-009417-458rrhcm	319	8	presumably	presumably	RB
cord-009417-458rrhcm	319	9	on	on	IN
cord-009417-458rrhcm	319	10	the	the	DT
cord-009417-458rrhcm	319	11	basis	basis	NN
cord-009417-458rrhcm	319	12	of	of	IN
cord-009417-458rrhcm	319	13	immune	immune	JJ
cord-009417-458rrhcm	319	14	complex	complex	JJ
cord-009417-458rrhcm	319	15	interactions	interaction	NNS
cord-009417-458rrhcm	319	16	.	.	.
cord-009417-458rrhcm	320	1	Morbidity	morbidity	NN
cord-009417-458rrhcm	320	2	and	and	CC
cord-009417-458rrhcm	320	3	mortality	mortality	NN
cord-009417-458rrhcm	320	4	are	be	VBP
cord-009417-458rrhcm	320	5	directly	directly	RB
cord-009417-458rrhcm	320	6	related	relate	VBN
cord-009417-458rrhcm	320	7	to	to	IN
cord-009417-458rrhcm	320	8	the	the	DT
cord-009417-458rrhcm	320	9	quantity	quantity	NN
cord-009417-458rrhcm	320	10	of	of	IN
cord-009417-458rrhcm	320	11	incompatible	incompatible	JJ
cord-009417-458rrhcm	320	12	blood	blood	NN
cord-009417-458rrhcm	320	13	transfused	transfuse	VBN
cord-009417-458rrhcm	320	14	,	,	,
cord-009417-458rrhcm	320	15	which	which	WDT
cord-009417-458rrhcm	320	16	is	be	VBZ
cord-009417-458rrhcm	320	17	why	why	WRB
cord-009417-458rrhcm	320	18	prompt	prompt	JJ
cord-009417-458rrhcm	320	19	recognition	recognition	NN
cord-009417-458rrhcm	320	20	and	and	CC
cord-009417-458rrhcm	320	21	cessation	cessation	NN
cord-009417-458rrhcm	320	22	of	of	IN
cord-009417-458rrhcm	320	23	transfusion	transfusion	NN
cord-009417-458rrhcm	320	24	can	can	MD
cord-009417-458rrhcm	320	25	not	not	RB
cord-009417-458rrhcm	320	26	be	be	VB
cord-009417-458rrhcm	320	27	overemphasized	overemphasize	VBN
cord-009417-458rrhcm	320	28	.	.	.
cord-009417-458rrhcm	321	1	Misidentifi	Misidentifi	NNP
cord-009417-458rrhcm	321	2	cation	cation	NN
cord-009417-458rrhcm	321	3	of	of	IN
cord-009417-458rrhcm	321	4	the	the	DT
cord-009417-458rrhcm	321	5	patient	patient	NN
cord-009417-458rrhcm	321	6	,	,	,
cord-009417-458rrhcm	321	7	or	or	CC
cord-009417-458rrhcm	321	8	"	"	``
cord-009417-458rrhcm	321	9	clerical	clerical	JJ
cord-009417-458rrhcm	321	10	error	error	NN
cord-009417-458rrhcm	321	11	,	,	,
cord-009417-458rrhcm	321	12	"	"	''
cord-009417-458rrhcm	321	13	at	at	IN
cord-009417-458rrhcm	321	14	any	any	DT
cord-009417-458rrhcm	321	15	time	time	NN
cord-009417-458rrhcm	321	16	beginning	begin	VBG
cord-009417-458rrhcm	321	17	with	with	IN
cord-009417-458rrhcm	321	18	the	the	DT
cord-009417-458rrhcm	321	19	process	process	NN
cord-009417-458rrhcm	321	20	of	of	IN
cord-009417-458rrhcm	321	21	specimen	specimen	JJ
cord-009417-458rrhcm	321	22	acquisition	acquisition	NN
cord-009417-458rrhcm	321	23	through	through	IN
cord-009417-458rrhcm	321	24	release	release	NN
cord-009417-458rrhcm	321	25	of	of	IN
cord-009417-458rrhcm	321	26	the	the	DT
cord-009417-458rrhcm	321	27	unit	unit	NN
cord-009417-458rrhcm	321	28	and	and	CC
cord-009417-458rrhcm	321	29	initiation	initiation	NN
cord-009417-458rrhcm	321	30	of	of	IN
cord-009417-458rrhcm	321	31	infusion	infusion	NN
cord-009417-458rrhcm	321	32	is	be	VBZ
cord-009417-458rrhcm	321	33	the	the	DT
cord-009417-458rrhcm	321	34	major	major	JJ
cord-009417-458rrhcm	321	35	cause	cause	NN
cord-009417-458rrhcm	321	36	of	of	IN
cord-009417-458rrhcm	321	37	acute	acute	JJ
cord-009417-458rrhcm	321	38	intravascular	intravascular	JJ
cord-009417-458rrhcm	321	39	hemolysis	hemolysis	NN
cord-009417-458rrhcm	321	40	.	.	.
cord-009417-458rrhcm	322	1	69	69	CD
cord-009417-458rrhcm	322	2	,	,	,
cord-009417-458rrhcm	322	3	70	70	CD
cord-009417-458rrhcm	323	1	This	this	DT
cord-009417-458rrhcm	323	2	reaction	reaction	NN
cord-009417-458rrhcm	323	3	is	be	VBZ
cord-009417-458rrhcm	323	4	more	more	RBR
cord-009417-458rrhcm	323	5	likely	likely	JJ
cord-009417-458rrhcm	323	6	to	to	TO
cord-009417-458rrhcm	323	7	occur	occur	VB
cord-009417-458rrhcm	323	8	in	in	IN
cord-009417-458rrhcm	323	9	critical	critical	JJ
cord-009417-458rrhcm	323	10	care	care	NN
cord-009417-458rrhcm	323	11	settings	setting	NNS
cord-009417-458rrhcm	323	12	,	,	,
cord-009417-458rrhcm	323	13	such	such	JJ
cord-009417-458rrhcm	323	14	as	as	IN
cord-009417-458rrhcm	323	15	the	the	DT
cord-009417-458rrhcm	323	16	ICU	ICU	NNP
cord-009417-458rrhcm	323	17	,	,	,
cord-009417-458rrhcm	323	18	operating	operating	NN
cord-009417-458rrhcm	323	19	room	room	NN
cord-009417-458rrhcm	323	20	,	,	,
cord-009417-458rrhcm	323	21	and	and	CC
cord-009417-458rrhcm	323	22	emergency	emergency	NN
cord-009417-458rrhcm	323	23	department	department	NN
cord-009417-458rrhcm	323	24	,	,	,
cord-009417-458rrhcm	323	25	than	than	IN
cord-009417-458rrhcm	323	26	anywhere	anywhere	RB
cord-009417-458rrhcm	323	27	else	else	RB
cord-009417-458rrhcm	323	28	in	in	IN
cord-009417-458rrhcm	323	29	the	the	DT
cord-009417-458rrhcm	323	30	hospital	hospital	NN
cord-009417-458rrhcm	323	31	.	.	.
cord-009417-458rrhcm	324	1	It	-PRON-	PRP
cord-009417-458rrhcm	324	2	is	be	VBZ
cord-009417-458rrhcm	324	3	far	far	RB
cord-009417-458rrhcm	324	4	preferable	preferable	JJ
cord-009417-458rrhcm	324	5	to	to	TO
cord-009417-458rrhcm	324	6	transfuse	transfuse	VB
cord-009417-458rrhcm	324	7	uncrossmatched	uncrossmatched	JJ
cord-009417-458rrhcm	324	8	group	group	NN
cord-009417-458rrhcm	324	9	O	o	NN
cord-009417-458rrhcm	324	10	red	red	JJ
cord-009417-458rrhcm	324	11	cells	cell	NNS
cord-009417-458rrhcm	324	12	than	than	IN
cord-009417-458rrhcm	324	13	to	to	TO
cord-009417-458rrhcm	324	14	chance	chance	VB
cord-009417-458rrhcm	324	15	ABO	ABO	NNP
cord-009417-458rrhcm	324	16	incompatibility	incompatibility	NN
cord-009417-458rrhcm	324	17	caused	cause	VBN
cord-009417-458rrhcm	324	18	by	by	IN
cord-009417-458rrhcm	324	19	improper	improper	JJ
cord-009417-458rrhcm	324	20	patient	patient	NN
cord-009417-458rrhcm	324	21	and	and	CC
cord-009417-458rrhcm	324	22	specimen	specimen	JJ
cord-009417-458rrhcm	324	23	identifi	identifi	NNP
cord-009417-458rrhcm	324	24	cation	cation	NN
cord-009417-458rrhcm	324	25	procedures	procedure	NNS
cord-009417-458rrhcm	324	26	.	.	.
cord-009417-458rrhcm	325	1	The	the	DT
cord-009417-458rrhcm	325	2	most	most	RBS
cord-009417-458rrhcm	325	3	common	common	JJ
cord-009417-458rrhcm	325	4	clinical	clinical	JJ
cord-009417-458rrhcm	325	5	sign	sign	NN
cord-009417-458rrhcm	325	6	of	of	IN
cord-009417-458rrhcm	325	7	hemolysis	hemolysis	NN
cord-009417-458rrhcm	325	8	is	be	VBZ
cord-009417-458rrhcm	325	9	fever	fever	NN
cord-009417-458rrhcm	325	10	,	,	,
cord-009417-458rrhcm	325	11	with	with	IN
cord-009417-458rrhcm	325	12	or	or	CC
cord-009417-458rrhcm	325	13	without	without	IN
cord-009417-458rrhcm	325	14	chills	chill	NNS
cord-009417-458rrhcm	325	15	.	.	.
cord-009417-458rrhcm	326	1	71	71	CD
cord-009417-458rrhcm	326	2	Other	other	JJ
cord-009417-458rrhcm	326	3	common	common	JJ
cord-009417-458rrhcm	326	4	signs	sign	NNS
cord-009417-458rrhcm	326	5	and	and	CC
cord-009417-458rrhcm	326	6	symptoms	symptom	NNS
cord-009417-458rrhcm	326	7	include	include	VBP
cord-009417-458rrhcm	326	8	back	back	RB
cord-009417-458rrhcm	326	9	or	or	CC
cord-009417-458rrhcm	326	10	fl	fl	NNP
cord-009417-458rrhcm	326	11	ank	ank	NNP
cord-009417-458rrhcm	326	12	pain	pain	NN
cord-009417-458rrhcm	326	13	,	,	,
cord-009417-458rrhcm	326	14	anxiety	anxiety	NN
cord-009417-458rrhcm	326	15	,	,	,
cord-009417-458rrhcm	326	16	nausea	nausea	NN
cord-009417-458rrhcm	326	17	,	,	,
cord-009417-458rrhcm	326	18	lightheadedness	lightheadedness	NN
cord-009417-458rrhcm	326	19	,	,	,
cord-009417-458rrhcm	326	20	dyspnea	dyspnea	NN
cord-009417-458rrhcm	326	21	,	,	,
cord-009417-458rrhcm	326	22	and	and	CC
cord-009417-458rrhcm	326	23	hemodynamic	hemodynamic	JJ
cord-009417-458rrhcm	326	24	instability	instability	NN
cord-009417-458rrhcm	326	25	.	.	.
cord-009417-458rrhcm	327	1	In	in	IN
cord-009417-458rrhcm	327	2	a	a	DT
cord-009417-458rrhcm	327	3	comatose	comatose	JJ
cord-009417-458rrhcm	327	4	or	or	CC
cord-009417-458rrhcm	327	5	anesthetized	anesthetize	VBN
cord-009417-458rrhcm	327	6	patient	patient	NN
cord-009417-458rrhcm	327	7	,	,	,
cord-009417-458rrhcm	327	8	many	many	JJ
cord-009417-458rrhcm	327	9	of	of	IN
cord-009417-458rrhcm	327	10	these	these	DT
cord-009417-458rrhcm	327	11	symptoms	symptom	NNS
cord-009417-458rrhcm	327	12	will	will	MD
cord-009417-458rrhcm	327	13	not	not	RB
cord-009417-458rrhcm	327	14	be	be	VB
cord-009417-458rrhcm	327	15	evident	evident	JJ
cord-009417-458rrhcm	327	16	;	;	:
cord-009417-458rrhcm	327	17	therefore	therefore	RB
cord-009417-458rrhcm	327	18	,	,	,
cord-009417-458rrhcm	327	19	signs	sign	NNS
cord-009417-458rrhcm	327	20	such	such	JJ
cord-009417-458rrhcm	327	21	as	as	IN
cord-009417-458rrhcm	327	22	hypotension	hypotension	NN
cord-009417-458rrhcm	327	23	,	,	,
cord-009417-458rrhcm	327	24	hemoglobinuria	hemoglobinuria	NNP
cord-009417-458rrhcm	327	25	,	,	,
cord-009417-458rrhcm	327	26	and	and	CC
cord-009417-458rrhcm	327	27	diffuse	diffuse	VB
cord-009417-458rrhcm	327	28	oozing	oozing	NN
cord-009417-458rrhcm	327	29	from	from	IN
cord-009417-458rrhcm	327	30	puncture	puncture	NN
cord-009417-458rrhcm	327	31	sites	site	NNS
cord-009417-458rrhcm	327	32	or	or	CC
cord-009417-458rrhcm	327	33	incisions	incision	NNS
cord-009417-458rrhcm	327	34	may	may	MD
cord-009417-458rrhcm	327	35	be	be	VB
cord-009417-458rrhcm	327	36	the	the	DT
cord-009417-458rrhcm	327	37	only	only	JJ
cord-009417-458rrhcm	327	38	notable	notable	JJ
cord-009417-458rrhcm	327	39	features	feature	NNS
cord-009417-458rrhcm	327	40	.	.	.
cord-009417-458rrhcm	328	1	Immediate	immediate	JJ
cord-009417-458rrhcm	328	2	management	management	NN
cord-009417-458rrhcm	328	3	of	of	IN
cord-009417-458rrhcm	328	4	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	328	5	transfusion	transfusion	NN
cord-009417-458rrhcm	328	6	reactions	reaction	NNS
cord-009417-458rrhcm	328	7	must	must	MD
cord-009417-458rrhcm	328	8	include	include	VB
cord-009417-458rrhcm	328	9	cessation	cessation	NN
cord-009417-458rrhcm	328	10	of	of	IN
cord-009417-458rrhcm	328	11	the	the	DT
cord-009417-458rrhcm	328	12	transfusion	transfusion	NN
cord-009417-458rrhcm	328	13	;	;	:
cord-009417-458rrhcm	328	14	the	the	DT
cord-009417-458rrhcm	328	15	remainder	remainder	NN
cord-009417-458rrhcm	328	16	of	of	IN
cord-009417-458rrhcm	328	17	care	care	NN
cord-009417-458rrhcm	328	18	is	be	VBZ
cord-009417-458rrhcm	328	19	supportive	supportive	JJ
cord-009417-458rrhcm	328	20	.	.	.
cord-009417-458rrhcm	329	1	Rapid	rapid	JJ
cord-009417-458rrhcm	329	2	verifi	verifi	NNP
cord-009417-458rrhcm	329	3	cation	cation	NN
cord-009417-458rrhcm	329	4	of	of	IN
cord-009417-458rrhcm	329	5	patient	patient	NNP
cord-009417-458rrhcm	329	6	and	and	CC
cord-009417-458rrhcm	329	7	unit	unit	NNP
cord-009417-458rrhcm	329	8	identifi	identifi	NNP
cord-009417-458rrhcm	329	9	cation	cation	NNP
cord-009417-458rrhcm	329	10	must	must	MD
cord-009417-458rrhcm	329	11	be	be	VB
cord-009417-458rrhcm	329	12	made	make	VBN
cord-009417-458rrhcm	329	13	,	,	,
cord-009417-458rrhcm	329	14	not	not	RB
cord-009417-458rrhcm	329	15	only	only	RB
cord-009417-458rrhcm	329	16	to	to	IN
cord-009417-458rrhcm	329	17	confi	confi	NNP
cord-009417-458rrhcm	329	18	rm	rm	NNP
cord-009417-458rrhcm	330	1	the	the	DT
cord-009417-458rrhcm	330	2	suspected	suspect	VBN
cord-009417-458rrhcm	330	3	reaction	reaction	NN
cord-009417-458rrhcm	330	4	but	but	CC
cord-009417-458rrhcm	330	5	also	also	RB
cord-009417-458rrhcm	331	1	to	to	TO
cord-009417-458rrhcm	331	2	prevent	prevent	VB
cord-009417-458rrhcm	331	3	a	a	DT
cord-009417-458rrhcm	331	4	second	second	JJ
cord-009417-458rrhcm	331	5	patient	patient	NN
cord-009417-458rrhcm	331	6	from	from	IN
cord-009417-458rrhcm	331	7	receiving	receive	VBG
cord-009417-458rrhcm	331	8	a	a	DT
cord-009417-458rrhcm	331	9	reciprocally	reciprocally	RB
cord-009417-458rrhcm	331	10	incompatible	incompatible	JJ
cord-009417-458rrhcm	331	11	unit	unit	NN
cord-009417-458rrhcm	331	12	if	if	IN
cord-009417-458rrhcm	331	13	a	a	DT
cord-009417-458rrhcm	331	14	clerical	clerical	JJ
cord-009417-458rrhcm	331	15	error	error	NN
cord-009417-458rrhcm	331	16	has	have	VBZ
cord-009417-458rrhcm	331	17	been	be	VBN
cord-009417-458rrhcm	331	18	made	make	VBN
cord-009417-458rrhcm	331	19	.	.	.
cord-009417-458rrhcm	332	1	Desired	desire	VBN
cord-009417-458rrhcm	332	2	end	end	NN
cord-009417-458rrhcm	332	3	points	point	NNS
cord-009417-458rrhcm	332	4	of	of	IN
cord-009417-458rrhcm	332	5	supportive	supportive	JJ
cord-009417-458rrhcm	332	6	care	care	NN
cord-009417-458rrhcm	332	7	include	include	VBP
cord-009417-458rrhcm	332	8	maintenance	maintenance	NN
cord-009417-458rrhcm	332	9	of	of	IN
cord-009417-458rrhcm	332	10	blood	blood	NN
cord-009417-458rrhcm	332	11	pressure	pressure	NN
cord-009417-458rrhcm	332	12	,	,	,
cord-009417-458rrhcm	332	13	high	high	JJ
cord-009417-458rrhcm	332	14	urine	urine	NN
cord-009417-458rrhcm	332	15	output	output	NN
cord-009417-458rrhcm	332	16	,	,	,
cord-009417-458rrhcm	332	17	and	and	CC
cord-009417-458rrhcm	332	18	support	support	NN
cord-009417-458rrhcm	332	19	of	of	IN
cord-009417-458rrhcm	332	20	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	332	21	or	or	CC
cord-009417-458rrhcm	332	22	further	further	JJ
cord-009417-458rrhcm	332	23	blood	blood	NN
cord-009417-458rrhcm	332	24	loss	loss	NN
cord-009417-458rrhcm	332	25	.	.	.
cord-009417-458rrhcm	333	1	Steroids	steroid	NNS
cord-009417-458rrhcm	333	2	,	,	,
cord-009417-458rrhcm	333	3	heparin	heparin	NN
cord-009417-458rrhcm	333	4	,	,	,
cord-009417-458rrhcm	333	5	or	or	CC
cord-009417-458rrhcm	333	6	other	other	JJ
cord-009417-458rrhcm	333	7	specifi	specifi	NN
cord-009417-458rrhcm	333	8	c	c	NN
cord-009417-458rrhcm	333	9	pharmacologic	pharmacologic	JJ
cord-009417-458rrhcm	333	10	interventions	intervention	NNS
cord-009417-458rrhcm	333	11	have	have	VBP
cord-009417-458rrhcm	333	12	no	no	DT
cord-009417-458rrhcm	333	13	role	role	NN
cord-009417-458rrhcm	333	14	in	in	IN
cord-009417-458rrhcm	333	15	treatment	treatment	NN
cord-009417-458rrhcm	333	16	.	.	.
cord-009417-458rrhcm	334	1	Anaphylactic	anaphylactic	JJ
cord-009417-458rrhcm	334	2	reactions	reaction	NNS
cord-009417-458rrhcm	334	3	to	to	IN
cord-009417-458rrhcm	334	4	blood	blood	NN
cord-009417-458rrhcm	334	5	transfusions	transfusion	NNS
cord-009417-458rrhcm	334	6	are	be	VBP
cord-009417-458rrhcm	334	7	fortunately	fortunately	RB
cord-009417-458rrhcm	334	8	rare	rare	JJ
cord-009417-458rrhcm	334	9	but	but	CC
cord-009417-458rrhcm	334	10	may	may	MD
cord-009417-458rrhcm	334	11	be	be	VB
cord-009417-458rrhcm	334	12	life	life	NN
cord-009417-458rrhcm	334	13	-	-	HYPH
cord-009417-458rrhcm	334	14	threatening	threaten	VBG
cord-009417-458rrhcm	334	15	.	.	.
cord-009417-458rrhcm	335	1	The	the	DT
cord-009417-458rrhcm	335	2	usual	usual	JJ
cord-009417-458rrhcm	335	3	cause	cause	NN
cord-009417-458rrhcm	335	4	is	be	VBZ
cord-009417-458rrhcm	335	5	recipient	recipient	NN
cord-009417-458rrhcm	335	6	antibody	antibody	NN
cord-009417-458rrhcm	335	7	to	to	IN
cord-009417-458rrhcm	335	8	a	a	DT
cord-009417-458rrhcm	335	9	component	component	NN
cord-009417-458rrhcm	335	10	of	of	IN
cord-009417-458rrhcm	335	11	plasma	plasma	NN
cord-009417-458rrhcm	335	12	that	that	IN
cord-009417-458rrhcm	335	13	the	the	DT
cord-009417-458rrhcm	335	14	patient	patient	NN
cord-009417-458rrhcm	335	15	lacks	lack	VBZ
cord-009417-458rrhcm	335	16	,	,	,
cord-009417-458rrhcm	335	17	most	most	RBS
cord-009417-458rrhcm	335	18	commonly	commonly	RB
cord-009417-458rrhcm	335	19	antibody	antibody	NN
cord-009417-458rrhcm	335	20	to	to	IN
cord-009417-458rrhcm	335	21	IgA	IgA	NNP
cord-009417-458rrhcm	335	22	in	in	IN
cord-009417-458rrhcm	335	23	IgAdefi	IgAdefi	NNP
cord-009417-458rrhcm	335	24	cient	cient	NN
cord-009417-458rrhcm	335	25	individuals	individual	NNS
cord-009417-458rrhcm	335	26	.	.	.
cord-009417-458rrhcm	336	1	72	72	CD
cord-009417-458rrhcm	336	2	Signs	sign	NNS
cord-009417-458rrhcm	336	3	and	and	CC
cord-009417-458rrhcm	336	4	symptoms	symptom	NNS
cord-009417-458rrhcm	336	5	include	include	VBP
cord-009417-458rrhcm	336	6	severe	severe	JJ
cord-009417-458rrhcm	336	7	malaise	malaise	NN
cord-009417-458rrhcm	336	8	and	and	CC
cord-009417-458rrhcm	336	9	anxiety	anxiety	NN
cord-009417-458rrhcm	336	10	,	,	,
cord-009417-458rrhcm	336	11	fl	fl	NNP
cord-009417-458rrhcm	336	12	ushing	ushing	NN
cord-009417-458rrhcm	336	13	,	,	,
cord-009417-458rrhcm	336	14	dizziness	dizziness	NN
cord-009417-458rrhcm	336	15	,	,	,
cord-009417-458rrhcm	336	16	dyspnea	dyspnea	NN
cord-009417-458rrhcm	336	17	,	,	,
cord-009417-458rrhcm	336	18	bronchospasm	bronchospasm	NN
cord-009417-458rrhcm	336	19	,	,	,
cord-009417-458rrhcm	336	20	abdominal	abdominal	JJ
cord-009417-458rrhcm	336	21	pain	pain	NN
cord-009417-458rrhcm	336	22	,	,	,
cord-009417-458rrhcm	336	23	vomiting	vomiting	NN
cord-009417-458rrhcm	336	24	,	,	,
cord-009417-458rrhcm	336	25	diarrhea	diarrhea	NN
cord-009417-458rrhcm	336	26	,	,	,
cord-009417-458rrhcm	336	27	hypotension	hypotension	NN
cord-009417-458rrhcm	336	28	,	,	,
cord-009417-458rrhcm	336	29	and	and	CC
cord-009417-458rrhcm	336	30	eventually	eventually	RB
cord-009417-458rrhcm	336	31	shock	shock	VB
cord-009417-458rrhcm	336	32	.	.	.
cord-009417-458rrhcm	337	1	Fever	fever	NN
cord-009417-458rrhcm	337	2	and	and	CC
cord-009417-458rrhcm	337	3	hemolysis	hemolysis	NN
cord-009417-458rrhcm	337	4	do	do	VBP
cord-009417-458rrhcm	337	5	not	not	RB
cord-009417-458rrhcm	337	6	occur	occur	VB
cord-009417-458rrhcm	337	7	.	.	.
cord-009417-458rrhcm	338	1	Management	management	NN
cord-009417-458rrhcm	338	2	includes	include	VBZ
cord-009417-458rrhcm	338	3	immediate	immediate	JJ
cord-009417-458rrhcm	338	4	cessation	cessation	NN
cord-009417-458rrhcm	338	5	of	of	IN
cord-009417-458rrhcm	338	6	transfusion	transfusion	NN
cord-009417-458rrhcm	338	7	and	and	CC
cord-009417-458rrhcm	338	8	standard	standard	JJ
cord-009417-458rrhcm	338	9	therapy	therapy	NN
cord-009417-458rrhcm	338	10	for	for	IN
cord-009417-458rrhcm	338	11	anaphylaxis	anaphylaxis	NN
cord-009417-458rrhcm	338	12	.	.	.
cord-009417-458rrhcm	339	1	If	if	IN
cord-009417-458rrhcm	339	2	anti	anti	JJ
cord-009417-458rrhcm	339	3	-	-	JJ
cord-009417-458rrhcm	339	4	IgA	iga	JJ
cord-009417-458rrhcm	339	5	antibodies	antibody	NNS
cord-009417-458rrhcm	339	6	are	be	VBP
cord-009417-458rrhcm	339	7	determined	determined	JJ
cord-009417-458rrhcm	339	8	to	to	TO
cord-009417-458rrhcm	339	9	be	be	VB
cord-009417-458rrhcm	339	10	the	the	DT
cord-009417-458rrhcm	339	11	cause	cause	NN
cord-009417-458rrhcm	339	12	of	of	IN
cord-009417-458rrhcm	339	13	this	this	DT
cord-009417-458rrhcm	339	14	reaction	reaction	NN
cord-009417-458rrhcm	339	15	,	,	,
cord-009417-458rrhcm	339	16	the	the	DT
cord-009417-458rrhcm	339	17	patient	patient	NN
cord-009417-458rrhcm	339	18	must	must	MD
cord-009417-458rrhcm	339	19	receive	receive	VB
cord-009417-458rrhcm	339	20	blood	blood	NN
cord-009417-458rrhcm	339	21	components	component	NNS
cord-009417-458rrhcm	339	22	donated	donate	VBN
cord-009417-458rrhcm	339	23	by	by	IN
cord-009417-458rrhcm	339	24	IgA	IgA	NNP
cord-009417-458rrhcm	339	25	-	-	HYPH
cord-009417-458rrhcm	339	26	defi	defi	NNP
cord-009417-458rrhcm	339	27	cient	cient	NNP
cord-009417-458rrhcm	339	28	individuals	individual	NNS
cord-009417-458rrhcm	339	29	or	or	CC
cord-009417-458rrhcm	339	30	,	,	,
cord-009417-458rrhcm	339	31	if	if	IN
cord-009417-458rrhcm	339	32	unavailable	unavailable	JJ
cord-009417-458rrhcm	339	33	,	,	,
cord-009417-458rrhcm	339	34	specially	specially	RB
cord-009417-458rrhcm	339	35	prepared	prepared	JJ
cord-009417-458rrhcm	339	36	washed	wash	VBN
cord-009417-458rrhcm	339	37	RBCs	rbc	NNS
cord-009417-458rrhcm	339	38	and	and	CC
cord-009417-458rrhcm	339	39	platelet	platelet	NN
cord-009417-458rrhcm	339	40	concentrates	concentrate	VBZ
cord-009417-458rrhcm	339	41	.	.	.
cord-009417-458rrhcm	340	1	Plasmaderived	plasmaderived	JJ
cord-009417-458rrhcm	340	2	preparations	preparation	NNS
cord-009417-458rrhcm	340	3	,	,	,
cord-009417-458rrhcm	340	4	such	such	JJ
cord-009417-458rrhcm	340	5	as	as	IN
cord-009417-458rrhcm	340	6	albumin	albumin	NN
cord-009417-458rrhcm	340	7	,	,	,
cord-009417-458rrhcm	340	8	and	and	CC
cord-009417-458rrhcm	340	9	IG	IG	NNP
cord-009417-458rrhcm	340	10	contain	contain	VBP
cord-009417-458rrhcm	340	11	varying	vary	VBG
cord-009417-458rrhcm	340	12	amounts	amount	NNS
cord-009417-458rrhcm	340	13	of	of	IN
cord-009417-458rrhcm	340	14	IgA	IgA	NNP
cord-009417-458rrhcm	340	15	and	and	CC
cord-009417-458rrhcm	340	16	pose	pose	VBP
cord-009417-458rrhcm	340	17	a	a	DT
cord-009417-458rrhcm	340	18	substantial	substantial	JJ
cord-009417-458rrhcm	340	19	risk	risk	NN
cord-009417-458rrhcm	340	20	in	in	IN
cord-009417-458rrhcm	340	21	these	these	DT
cord-009417-458rrhcm	340	22	patients	patient	NNS
cord-009417-458rrhcm	340	23	.	.	.
cord-009417-458rrhcm	341	1	Febrile	febrile	JJ
cord-009417-458rrhcm	341	2	nonhemolytic	nonhemolytic	JJ
cord-009417-458rrhcm	341	3	reactions	reaction	NNS
cord-009417-458rrhcm	341	4	(	(	-LRB-
cord-009417-458rrhcm	341	5	FNHRs	fnhr	NNS
cord-009417-458rrhcm	341	6	)	)	-RRB-
cord-009417-458rrhcm	341	7	are	be	VBP
cord-009417-458rrhcm	341	8	the	the	DT
cord-009417-458rrhcm	341	9	most	most	RBS
cord-009417-458rrhcm	341	10	commonly	commonly	RB
cord-009417-458rrhcm	341	11	occurring	occur	VBG
cord-009417-458rrhcm	341	12	immediate	immediate	JJ
cord-009417-458rrhcm	341	13	transfusion	transfusion	NN
cord-009417-458rrhcm	341	14	reaction	reaction	NN
cord-009417-458rrhcm	341	15	.	.	.
cord-009417-458rrhcm	342	1	These	these	DT
cord-009417-458rrhcm	342	2	reactions	reaction	NNS
cord-009417-458rrhcm	342	3	are	be	VBP
cord-009417-458rrhcm	342	4	annoying	annoying	JJ
cord-009417-458rrhcm	342	5	to	to	IN
cord-009417-458rrhcm	342	6	the	the	DT
cord-009417-458rrhcm	342	7	clinician	clinician	NN
cord-009417-458rrhcm	342	8	,	,	,
cord-009417-458rrhcm	342	9	patient	patient	JJ
cord-009417-458rrhcm	342	10	,	,	,
cord-009417-458rrhcm	342	11	and	and	CC
cord-009417-458rrhcm	342	12	transfusion	transfusion	NN
cord-009417-458rrhcm	342	13	service	service	NN
cord-009417-458rrhcm	342	14	alike	alike	RB
cord-009417-458rrhcm	342	15	in	in	IN
cord-009417-458rrhcm	342	16	that	that	IN
cord-009417-458rrhcm	342	17	they	-PRON-	PRP
cord-009417-458rrhcm	342	18	can	can	MD
cord-009417-458rrhcm	342	19	cause	cause	VB
cord-009417-458rrhcm	342	20	signifi	signifi	NNP
cord-009417-458rrhcm	342	21	ca	can	MD
cord-009417-458rrhcm	342	22	nt	not	RB
cord-009417-458rrhcm	342	23	discomfort	discomfort	VB
cord-009417-458rrhcm	342	24	and	and	CC
cord-009417-458rrhcm	342	25	,	,	,
cord-009417-458rrhcm	342	26	because	because	IN
cord-009417-458rrhcm	342	27	they	-PRON-	PRP
cord-009417-458rrhcm	342	28	share	share	VBP
cord-009417-458rrhcm	342	29	certain	certain	JJ
cord-009417-458rrhcm	342	30	manifestations	manifestation	NNS
cord-009417-458rrhcm	342	31	with	with	IN
cord-009417-458rrhcm	342	32	acute	acute	JJ
cord-009417-458rrhcm	342	33	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	342	34	reactions	reaction	NNS
cord-009417-458rrhcm	342	35	,	,	,
cord-009417-458rrhcm	342	36	must	must	MD
cord-009417-458rrhcm	342	37	be	be	VB
cord-009417-458rrhcm	342	38	investigated	investigate	VBN
cord-009417-458rrhcm	342	39	in	in	IN
cord-009417-458rrhcm	342	40	every	every	DT
cord-009417-458rrhcm	342	41	instance	instance	NN
cord-009417-458rrhcm	342	42	.	.	.
cord-009417-458rrhcm	343	1	FNHRs	fnhr	NNS
cord-009417-458rrhcm	343	2	occur	occur	VBP
cord-009417-458rrhcm	343	3	in	in	IN
cord-009417-458rrhcm	343	4	approximately	approximately	RB
cord-009417-458rrhcm	343	5	0.5	0.5	CD
cord-009417-458rrhcm	343	6	%	%	NN
cord-009417-458rrhcm	343	7	to	to	IN
cord-009417-458rrhcm	343	8	1.0	1.0	CD
cord-009417-458rrhcm	343	9	%	%	NN
cord-009417-458rrhcm	343	10	of	of	IN
cord-009417-458rrhcm	343	11	transfusion	transfusion	NN
cord-009417-458rrhcm	343	12	episodes	episode	NNS
cord-009417-458rrhcm	343	13	.	.	.
cord-009417-458rrhcm	344	1	73	73	CD
cord-009417-458rrhcm	345	1	The	the	DT
cord-009417-458rrhcm	345	2	etiologic	etiologic	JJ
cord-009417-458rrhcm	345	3	factors	factor	NNS
cord-009417-458rrhcm	345	4	are	be	VBP
cord-009417-458rrhcm	345	5	probably	probably	RB
cord-009417-458rrhcm	345	6	complex	complex	JJ
cord-009417-458rrhcm	345	7	and	and	CC
cord-009417-458rrhcm	345	8	multiple	multiple	JJ
cord-009417-458rrhcm	345	9	,	,	,
cord-009417-458rrhcm	345	10	but	but	CC
cord-009417-458rrhcm	345	11	many	many	JJ
cord-009417-458rrhcm	345	12	reactions	reaction	NNS
cord-009417-458rrhcm	345	13	are	be	VBP
cord-009417-458rrhcm	345	14	caused	cause	VBN
cord-009417-458rrhcm	345	15	by	by	IN
cord-009417-458rrhcm	345	16	the	the	DT
cord-009417-458rrhcm	345	17	release	release	NN
cord-009417-458rrhcm	345	18	of	of	IN
cord-009417-458rrhcm	345	19	cytokines	cytokine	NNS
cord-009417-458rrhcm	345	20	and	and	CC
cord-009417-458rrhcm	345	21	pyrogens	pyrogen	NNS
cord-009417-458rrhcm	345	22	,	,	,
cord-009417-458rrhcm	345	23	either	either	CC
cord-009417-458rrhcm	345	24	within	within	IN
cord-009417-458rrhcm	345	25	the	the	DT
cord-009417-458rrhcm	345	26	transfused	transfuse	VBN
cord-009417-458rrhcm	345	27	unit	unit	NN
cord-009417-458rrhcm	345	28	of	of	IN
cord-009417-458rrhcm	345	29	blood	blood	NN
cord-009417-458rrhcm	345	30	or	or	CC
cord-009417-458rrhcm	345	31	as	as	IN
cord-009417-458rrhcm	345	32	a	a	DT
cord-009417-458rrhcm	345	33	result	result	NN
cord-009417-458rrhcm	345	34	of	of	IN
cord-009417-458rrhcm	345	35	recipient	recipient	NN
cord-009417-458rrhcm	345	36	antibodies	antibody	NNS
cord-009417-458rrhcm	345	37	to	to	IN
cord-009417-458rrhcm	345	38	donor	donor	NN
cord-009417-458rrhcm	345	39	leukocytes	leukocyte	NNS
cord-009417-458rrhcm	345	40	.	.	.
cord-009417-458rrhcm	346	1	Clinical	clinical	JJ
cord-009417-458rrhcm	346	2	signs	sign	NNS
cord-009417-458rrhcm	346	3	include	include	VBP
cord-009417-458rrhcm	346	4	fever	fever	NN
cord-009417-458rrhcm	346	5	,	,	,
cord-009417-458rrhcm	346	6	with	with	IN
cord-009417-458rrhcm	346	7	or	or	CC
cord-009417-458rrhcm	346	8	without	without	IN
cord-009417-458rrhcm	346	9	chills	chill	NNS
cord-009417-458rrhcm	346	10	,	,	,
cord-009417-458rrhcm	346	11	usually	usually	RB
cord-009417-458rrhcm	346	12	beginning	begin	VBG
cord-009417-458rrhcm	346	13	1	1	CD
cord-009417-458rrhcm	346	14	to	to	IN
cord-009417-458rrhcm	346	15	2	2	CD
cord-009417-458rrhcm	346	16	hours	hour	NNS
cord-009417-458rrhcm	346	17	after	after	IN
cord-009417-458rrhcm	346	18	the	the	DT
cord-009417-458rrhcm	346	19	start	start	NN
cord-009417-458rrhcm	346	20	of	of	IN
cord-009417-458rrhcm	346	21	the	the	DT
cord-009417-458rrhcm	346	22	transfusion	transfusion	NN
cord-009417-458rrhcm	346	23	but	but	CC
cord-009417-458rrhcm	346	24	occasionally	occasionally	RB
cord-009417-458rrhcm	346	25	delayed	delay	VBD
cord-009417-458rrhcm	346	26	up	up	RP
cord-009417-458rrhcm	346	27	to	to	IN
cord-009417-458rrhcm	346	28	4	4	CD
cord-009417-458rrhcm	346	29	to	to	TO
cord-009417-458rrhcm	346	30	6	6	CD
cord-009417-458rrhcm	346	31	hours	hour	NNS
cord-009417-458rrhcm	346	32	.	.	.
cord-009417-458rrhcm	347	1	Multiparous	multiparous	JJ
cord-009417-458rrhcm	347	2	women	woman	NNS
cord-009417-458rrhcm	347	3	and	and	CC
cord-009417-458rrhcm	347	4	patients	patient	NNS
cord-009417-458rrhcm	347	5	who	who	WP
cord-009417-458rrhcm	347	6	are	be	VBP
cord-009417-458rrhcm	347	7	multiply	multiply	RB
cord-009417-458rrhcm	347	8	transfused	transfuse	VBN
cord-009417-458rrhcm	347	9	are	be	VBP
cord-009417-458rrhcm	347	10	particularly	particularly	RB
cord-009417-458rrhcm	347	11	prone	prone	JJ
cord-009417-458rrhcm	347	12	to	to	IN
cord-009417-458rrhcm	347	13	FNHRs	fnhr	NNS
cord-009417-458rrhcm	347	14	.	.	.
cord-009417-458rrhcm	348	1	The	the	DT
cord-009417-458rrhcm	348	2	transfusion	transfusion	NN
cord-009417-458rrhcm	348	3	must	must	MD
cord-009417-458rrhcm	348	4	be	be	VB
cord-009417-458rrhcm	348	5	stopped	stop	VBN
cord-009417-458rrhcm	348	6	and	and	CC
cord-009417-458rrhcm	348	7	the	the	DT
cord-009417-458rrhcm	348	8	appropriate	appropriate	JJ
cord-009417-458rrhcm	348	9	transfusion	transfusion	NN
cord-009417-458rrhcm	348	10	reaction	reaction	NN
cord-009417-458rrhcm	348	11	evaluation	evaluation	NN
cord-009417-458rrhcm	348	12	instituted	institute	VBN
cord-009417-458rrhcm	348	13	.	.	.
cord-009417-458rrhcm	349	1	Antipyretics	antipyretic	NNS
cord-009417-458rrhcm	349	2	such	such	JJ
cord-009417-458rrhcm	349	3	as	as	IN
cord-009417-458rrhcm	349	4	acetaminophen	acetaminophen	NN
cord-009417-458rrhcm	349	5	may	may	MD
cord-009417-458rrhcm	349	6	be	be	VB
cord-009417-458rrhcm	349	7	administered	administer	VBN
cord-009417-458rrhcm	349	8	.	.	.
cord-009417-458rrhcm	350	1	Though	though	IN
cord-009417-458rrhcm	350	2	commonly	commonly	RB
cord-009417-458rrhcm	350	3	used	use	VBN
cord-009417-458rrhcm	350	4	,	,	,
cord-009417-458rrhcm	350	5	antihistamines	antihistamine	NNS
cord-009417-458rrhcm	350	6	such	such	JJ
cord-009417-458rrhcm	350	7	as	as	IN
cord-009417-458rrhcm	350	8	diphenhydramine	diphenhydramine	NN
cord-009417-458rrhcm	350	9	are	be	VBP
cord-009417-458rrhcm	350	10	neither	neither	CC
cord-009417-458rrhcm	350	11	preventive	preventive	JJ
cord-009417-458rrhcm	350	12	nor	nor	CC
cord-009417-458rrhcm	350	13	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	350	14	.	.	.
cord-009417-458rrhcm	351	1	Once	once	IN
cord-009417-458rrhcm	351	2	acute	acute	JJ
cord-009417-458rrhcm	351	3	hemolysis	hemolysis	NN
cord-009417-458rrhcm	351	4	is	be	VBZ
cord-009417-458rrhcm	351	5	excluded	exclude	VBN
cord-009417-458rrhcm	351	6	,	,	,
cord-009417-458rrhcm	351	7	transfusion	transfusion	NN
cord-009417-458rrhcm	351	8	of	of	IN
cord-009417-458rrhcm	351	9	a	a	DT
cord-009417-458rrhcm	351	10	new	new	JJ
cord-009417-458rrhcm	351	11	unit	unit	NN
cord-009417-458rrhcm	351	12	may	may	MD
cord-009417-458rrhcm	351	13	be	be	VB
cord-009417-458rrhcm	351	14	instituted	institute	VBN
cord-009417-458rrhcm	351	15	.	.	.
cord-009417-458rrhcm	352	1	Most	Most	JJS
cord-009417-458rrhcm	352	2	patients	patient	NNS
cord-009417-458rrhcm	352	3	will	will	MD
cord-009417-458rrhcm	352	4	not	not	RB
cord-009417-458rrhcm	352	5	experience	experience	VB
cord-009417-458rrhcm	352	6	a	a	DT
cord-009417-458rrhcm	352	7	second	second	JJ
cord-009417-458rrhcm	352	8	such	such	JJ
cord-009417-458rrhcm	352	9	reaction	reaction	NN
cord-009417-458rrhcm	352	10	.	.	.
cord-009417-458rrhcm	353	1	73	73	CD
cord-009417-458rrhcm	354	1	If	if	IN
cord-009417-458rrhcm	354	2	repeated	repeat	VBN
cord-009417-458rrhcm	354	3	reactions	reaction	NNS
cord-009417-458rrhcm	354	4	become	become	VBP
cord-009417-458rrhcm	354	5	problematic	problematic	JJ
cord-009417-458rrhcm	354	6	,	,	,
cord-009417-458rrhcm	354	7	leukocyte	leukocyte	NN
cord-009417-458rrhcm	354	8	-	-	HYPH
cord-009417-458rrhcm	354	9	depleted	deplete	VBN
cord-009417-458rrhcm	354	10	blood	blood	NN
cord-009417-458rrhcm	354	11	components	component	NNS
cord-009417-458rrhcm	354	12	may	may	MD
cord-009417-458rrhcm	354	13	be	be	VB
cord-009417-458rrhcm	354	14	supplied	supply	VBN
cord-009417-458rrhcm	354	15	.	.	.
cord-009417-458rrhcm	355	1	The	the	DT
cord-009417-458rrhcm	355	2	implementation	implementation	NN
cord-009417-458rrhcm	355	3	of	of	IN
cord-009417-458rrhcm	355	4	ULR	ULR	NNP
cord-009417-458rrhcm	355	5	results	result	NNS
cord-009417-458rrhcm	355	6	in	in	IN
cord-009417-458rrhcm	355	7	a	a	DT
cord-009417-458rrhcm	355	8	reduction	reduction	NN
cord-009417-458rrhcm	355	9	in	in	IN
cord-009417-458rrhcm	355	10	the	the	DT
cord-009417-458rrhcm	355	11	frequency	frequency	NN
cord-009417-458rrhcm	355	12	of	of	IN
cord-009417-458rrhcm	355	13	all	all	DT
cord-009417-458rrhcm	355	14	fevers	fever	NNS
cord-009417-458rrhcm	355	15	seen	see	VBN
cord-009417-458rrhcm	355	16	after	after	IN
cord-009417-458rrhcm	355	17	transfusion	transfusion	NN
cord-009417-458rrhcm	355	18	by	by	IN
cord-009417-458rrhcm	355	19	only	only	RB
cord-009417-458rrhcm	355	20	about	about	RB
cord-009417-458rrhcm	355	21	12	12	CD
cord-009417-458rrhcm	355	22	%	%	NN
cord-009417-458rrhcm	355	23	.	.	.
cord-009417-458rrhcm	356	1	74	74	CD
cord-009417-458rrhcm	356	2	Hives	hive	NNS
cord-009417-458rrhcm	356	3	and	and	CC
cord-009417-458rrhcm	356	4	pruritus	pruritus	NN
cord-009417-458rrhcm	356	5	are	be	VBP
cord-009417-458rrhcm	356	6	relatively	relatively	RB
cord-009417-458rrhcm	356	7	common	common	JJ
cord-009417-458rrhcm	356	8	adverse	adverse	JJ
cord-009417-458rrhcm	356	9	effects	effect	NNS
cord-009417-458rrhcm	356	10	of	of	IN
cord-009417-458rrhcm	356	11	transfusion	transfusion	NN
cord-009417-458rrhcm	356	12	.	.	.
cord-009417-458rrhcm	357	1	68	68	CD
cord-009417-458rrhcm	358	1	They	-PRON-	PRP
cord-009417-458rrhcm	358	2	are	be	VBP
cord-009417-458rrhcm	358	3	a	a	DT
cord-009417-458rrhcm	358	4	hypersensitivity	hypersensitivity	NN
cord-009417-458rrhcm	358	5	reaction	reaction	NN
cord-009417-458rrhcm	358	6	localized	localize	VBN
cord-009417-458rrhcm	358	7	to	to	IN
cord-009417-458rrhcm	358	8	the	the	DT
cord-009417-458rrhcm	358	9	skin	skin	NN
cord-009417-458rrhcm	358	10	,	,	,
cord-009417-458rrhcm	358	11	and	and	CC
cord-009417-458rrhcm	358	12	their	-PRON-	PRP$
cord-009417-458rrhcm	358	13	cause	cause	NN
cord-009417-458rrhcm	358	14	is	be	VBZ
cord-009417-458rrhcm	358	15	unknown	unknown	JJ
cord-009417-458rrhcm	358	16	but	but	CC
cord-009417-458rrhcm	358	17	may	may	MD
cord-009417-458rrhcm	358	18	include	include	VB
cord-009417-458rrhcm	358	19	both	both	DT
cord-009417-458rrhcm	358	20	donor	donor	NN
cord-009417-458rrhcm	358	21	and	and	CC
cord-009417-458rrhcm	358	22	recipient	recipient	NN
cord-009417-458rrhcm	358	23	characteristics	characteristic	NNS
cord-009417-458rrhcm	358	24	.	.	.
cord-009417-458rrhcm	359	1	These	these	DT
cord-009417-458rrhcm	359	2	reactions	reaction	NNS
cord-009417-458rrhcm	359	3	consist	consist	VBP
cord-009417-458rrhcm	359	4	of	of	IN
cord-009417-458rrhcm	359	5	localized	localized	JJ
cord-009417-458rrhcm	359	6	or	or	CC
cord-009417-458rrhcm	359	7	generalized	generalize	VBN
cord-009417-458rrhcm	359	8	urticaria	urticaria	NN
cord-009417-458rrhcm	359	9	beginning	begin	VBG
cord-009417-458rrhcm	359	10	shortly	shortly	RB
cord-009417-458rrhcm	359	11	after	after	IN
cord-009417-458rrhcm	359	12	the	the	DT
cord-009417-458rrhcm	359	13	start	start	NN
cord-009417-458rrhcm	359	14	of	of	IN
cord-009417-458rrhcm	359	15	transfusion	transfusion	NN
cord-009417-458rrhcm	359	16	without	without	IN
cord-009417-458rrhcm	359	17	other	other	JJ
cord-009417-458rrhcm	359	18	signs	sign	NNS
cord-009417-458rrhcm	359	19	or	or	CC
cord-009417-458rrhcm	359	20	symptoms	symptom	NNS
cord-009417-458rrhcm	359	21	of	of	IN
cord-009417-458rrhcm	359	22	anaphylaxis	anaphylaxis	NN
cord-009417-458rrhcm	359	23	or	or	CC
cord-009417-458rrhcm	359	24	hemolysis	hemolysis	NN
cord-009417-458rrhcm	359	25	.	.	.
cord-009417-458rrhcm	360	1	The	the	DT
cord-009417-458rrhcm	360	2	transfusion	transfusion	NN
cord-009417-458rrhcm	360	3	should	should	MD
cord-009417-458rrhcm	360	4	be	be	VB
cord-009417-458rrhcm	360	5	temporarily	temporarily	RB
cord-009417-458rrhcm	360	6	stopped	stop	VBN
cord-009417-458rrhcm	360	7	,	,	,
cord-009417-458rrhcm	360	8	and	and	CC
cord-009417-458rrhcm	360	9	antihistamines	antihistamine	NNS
cord-009417-458rrhcm	360	10	may	may	MD
cord-009417-458rrhcm	360	11	be	be	VB
cord-009417-458rrhcm	360	12	administered	administer	VBN
cord-009417-458rrhcm	360	13	.	.	.
cord-009417-458rrhcm	361	1	If	if	IN
cord-009417-458rrhcm	361	2	the	the	DT
cord-009417-458rrhcm	361	3	hives	hive	NNS
cord-009417-458rrhcm	361	4	resolve	resolve	VBP
cord-009417-458rrhcm	361	5	in	in	IN
cord-009417-458rrhcm	361	6	a	a	DT
cord-009417-458rrhcm	361	7	short	short	JJ
cord-009417-458rrhcm	361	8	time	time	NN
cord-009417-458rrhcm	361	9	,	,	,
cord-009417-458rrhcm	361	10	the	the	DT
cord-009417-458rrhcm	361	11	same	same	JJ
cord-009417-458rrhcm	361	12	unit	unit	NN
cord-009417-458rrhcm	361	13	of	of	IN
cord-009417-458rrhcm	361	14	blood	blood	NN
cord-009417-458rrhcm	361	15	may	may	MD
cord-009417-458rrhcm	361	16	be	be	VB
cord-009417-458rrhcm	361	17	cautiously	cautiously	RB
cord-009417-458rrhcm	361	18	restarted	restart	VBN
cord-009417-458rrhcm	361	19	.	.	.
cord-009417-458rrhcm	362	1	If	if	IN
cord-009417-458rrhcm	362	2	repeated	repeat	VBN
cord-009417-458rrhcm	362	3	urticarial	urticarial	JJ
cord-009417-458rrhcm	362	4	reactions	reaction	NNS
cord-009417-458rrhcm	362	5	occur	occur	VBP
cord-009417-458rrhcm	362	6	,	,	,
cord-009417-458rrhcm	362	7	premedication	premedication	NN
cord-009417-458rrhcm	362	8	with	with	IN
cord-009417-458rrhcm	362	9	antihistamines	antihistamine	NNS
cord-009417-458rrhcm	362	10	may	may	MD
cord-009417-458rrhcm	362	11	be	be	VB
cord-009417-458rrhcm	362	12	effective	effective	JJ
cord-009417-458rrhcm	362	13	,	,	,
cord-009417-458rrhcm	362	14	or	or	CC
cord-009417-458rrhcm	362	15	blood	blood	NN
cord-009417-458rrhcm	362	16	components	component	NNS
cord-009417-458rrhcm	362	17	washed	wash	VBD
cord-009417-458rrhcm	362	18	to	to	TO
cord-009417-458rrhcm	362	19	remove	remove	VB
cord-009417-458rrhcm	362	20	plasma	plasma	NN
cord-009417-458rrhcm	362	21	may	may	MD
cord-009417-458rrhcm	362	22	be	be	VB
cord-009417-458rrhcm	362	23	required	require	VBN
cord-009417-458rrhcm	362	24	.	.	.
cord-009417-458rrhcm	363	1	Intravascular	Intravascular	NNP
cord-009417-458rrhcm	363	2	volume	volume	NN
cord-009417-458rrhcm	363	3	overexpansion	overexpansion	NN
cord-009417-458rrhcm	363	4	is	be	VBZ
cord-009417-458rrhcm	363	5	particularly	particularly	RB
cord-009417-458rrhcm	363	6	likely	likely	JJ
cord-009417-458rrhcm	363	7	to	to	TO
cord-009417-458rrhcm	363	8	occur	occur	VB
cord-009417-458rrhcm	363	9	in	in	IN
cord-009417-458rrhcm	363	10	critical	critical	JJ
cord-009417-458rrhcm	363	11	care	care	NN
cord-009417-458rrhcm	363	12	patients	patient	NNS
cord-009417-458rrhcm	363	13	with	with	IN
cord-009417-458rrhcm	363	14	limited	limited	JJ
cord-009417-458rrhcm	363	15	cardiac	cardiac	JJ
cord-009417-458rrhcm	363	16	reserve	reserve	NN
cord-009417-458rrhcm	363	17	.	.	.
cord-009417-458rrhcm	364	1	Aside	aside	RB
cord-009417-458rrhcm	364	2	from	from	IN
cord-009417-458rrhcm	364	3	the	the	DT
cord-009417-458rrhcm	364	4	inherent	inherent	JJ
cord-009417-458rrhcm	364	5	volume	volume	NN
cord-009417-458rrhcm	364	6	of	of	IN
cord-009417-458rrhcm	364	7	the	the	DT
cord-009417-458rrhcm	364	8	blood	blood	NN
cord-009417-458rrhcm	364	9	components	component	NNS
cord-009417-458rrhcm	364	10	,	,	,
cord-009417-458rrhcm	364	11	the	the	DT
cord-009417-458rrhcm	364	12	intravenous	intravenous	JJ
cord-009417-458rrhcm	364	13	normal	normal	JJ
cord-009417-458rrhcm	364	14	saline	saline	NN
cord-009417-458rrhcm	364	15	concurrently	concurrently	RB
cord-009417-458rrhcm	364	16	administered	administer	VBN
cord-009417-458rrhcm	364	17	adds	add	VBZ
cord-009417-458rrhcm	364	18	to	to	IN
cord-009417-458rrhcm	364	19	the	the	DT
cord-009417-458rrhcm	364	20	volume	volume	NN
cord-009417-458rrhcm	364	21	load	load	NN
cord-009417-458rrhcm	364	22	.	.	.
cord-009417-458rrhcm	365	1	Unfortunately	unfortunately	RB
cord-009417-458rrhcm	365	2	,	,	,
cord-009417-458rrhcm	365	3	normal	normal	JJ
cord-009417-458rrhcm	365	4	saline	saline	NN
cord-009417-458rrhcm	365	5	solution	solution	NN
cord-009417-458rrhcm	365	6	is	be	VBZ
cord-009417-458rrhcm	365	7	the	the	DT
cord-009417-458rrhcm	365	8	only	only	JJ
cord-009417-458rrhcm	365	9	intravenous	intravenous	JJ
cord-009417-458rrhcm	365	10	fl	fl	NNP
cord-009417-458rrhcm	365	11	uid	uid	NNS
cord-009417-458rrhcm	365	12	that	that	WDT
cord-009417-458rrhcm	365	13	may	may	MD
cord-009417-458rrhcm	365	14	be	be	VB
cord-009417-458rrhcm	365	15	administered	administer	VBN
cord-009417-458rrhcm	365	16	with	with	IN
cord-009417-458rrhcm	365	17	blood	blood	NN
cord-009417-458rrhcm	365	18	components	component	NNS
cord-009417-458rrhcm	365	19	.	.	.
cord-009417-458rrhcm	366	1	With	with	IN
cord-009417-458rrhcm	366	2	careful	careful	JJ
cord-009417-458rrhcm	366	3	attention	attention	NN
cord-009417-458rrhcm	366	4	to	to	IN
cord-009417-458rrhcm	366	5	transfusion	transfusion	NN
cord-009417-458rrhcm	366	6	requirements	requirement	NNS
cord-009417-458rrhcm	366	7	and	and	CC
cord-009417-458rrhcm	366	8	the	the	DT
cord-009417-458rrhcm	366	9	use	use	NN
cord-009417-458rrhcm	366	10	of	of	IN
cord-009417-458rrhcm	366	11	volume	volume	NN
cord-009417-458rrhcm	366	12	reduction	reduction	NN
cord-009417-458rrhcm	366	13	maneuvers	maneuver	NNS
cord-009417-458rrhcm	366	14	available	available	JJ
cord-009417-458rrhcm	366	15	to	to	IN
cord-009417-458rrhcm	366	16	the	the	DT
cord-009417-458rrhcm	366	17	transfusion	transfusion	NN
cord-009417-458rrhcm	366	18	service	service	NN
cord-009417-458rrhcm	366	19	,	,	,
cord-009417-458rrhcm	366	20	volume	volume	NN
cord-009417-458rrhcm	366	21	overload	overload	NN
cord-009417-458rrhcm	366	22	can	can	MD
cord-009417-458rrhcm	366	23	be	be	VB
cord-009417-458rrhcm	366	24	minimized	minimize	VBN
cord-009417-458rrhcm	366	25	in	in	IN
cord-009417-458rrhcm	366	26	most	most	JJS
cord-009417-458rrhcm	366	27	instances	instance	NNS
cord-009417-458rrhcm	366	28	.	.	.
cord-009417-458rrhcm	367	1	The	the	DT
cord-009417-458rrhcm	367	2	frequency	frequency	NN
cord-009417-458rrhcm	367	3	of	of	IN
cord-009417-458rrhcm	367	4	this	this	DT
cord-009417-458rrhcm	367	5	complication	complication	NN
cord-009417-458rrhcm	367	6	of	of	IN
cord-009417-458rrhcm	367	7	transfusion	transfusion	NN
cord-009417-458rrhcm	367	8	is	be	VBZ
cord-009417-458rrhcm	367	9	not	not	RB
cord-009417-458rrhcm	367	10	reported	report	VBN
cord-009417-458rrhcm	367	11	.	.	.
cord-009417-458rrhcm	368	1	Delayed	delayed	JJ
cord-009417-458rrhcm	368	2	hemolysis	hemolysis	NN
cord-009417-458rrhcm	368	3	is	be	VBZ
cord-009417-458rrhcm	368	4	an	an	DT
cord-009417-458rrhcm	368	5	uncommon	uncommon	JJ
cord-009417-458rrhcm	368	6	but	but	CC
cord-009417-458rrhcm	368	7	probably	probably	RB
cord-009417-458rrhcm	368	8	underrecognized	underrecognize	VBD
cord-009417-458rrhcm	368	9	reaction	reaction	NN
cord-009417-458rrhcm	368	10	to	to	IN
cord-009417-458rrhcm	368	11	transfusion	transfusion	NN
cord-009417-458rrhcm	368	12	that	that	WDT
cord-009417-458rrhcm	368	13	results	result	VBZ
cord-009417-458rrhcm	368	14	from	from	IN
cord-009417-458rrhcm	368	15	the	the	DT
cord-009417-458rrhcm	368	16	stimulation	stimulation	NN
cord-009417-458rrhcm	368	17	of	of	IN
cord-009417-458rrhcm	368	18	a	a	DT
cord-009417-458rrhcm	368	19	primary	primary	JJ
cord-009417-458rrhcm	368	20	or	or	CC
cord-009417-458rrhcm	368	21	secondary	secondary	JJ
cord-009417-458rrhcm	368	22	(	(	-LRB-
cord-009417-458rrhcm	368	23	anamnestic	anamnestic	JJ
cord-009417-458rrhcm	368	24	)	)	-RRB-
cord-009417-458rrhcm	368	25	recipient	recipient	NN
cord-009417-458rrhcm	368	26	antibody	antibody	NN
cord-009417-458rrhcm	368	27	response	response	NN
cord-009417-458rrhcm	368	28	to	to	IN
cord-009417-458rrhcm	368	29	foreign	foreign	JJ
cord-009417-458rrhcm	368	30	RBC	RBC	NNP
cord-009417-458rrhcm	368	31	antigens	antigen	NNS
cord-009417-458rrhcm	368	32	.	.	.
cord-009417-458rrhcm	369	1	These	these	DT
cord-009417-458rrhcm	369	2	antibodies	antibody	NNS
cord-009417-458rrhcm	369	3	are	be	VBP
cord-009417-458rrhcm	369	4	undetected	undetected	JJ
cord-009417-458rrhcm	369	5	at	at	IN
cord-009417-458rrhcm	369	6	the	the	DT
cord-009417-458rrhcm	369	7	time	time	NN
cord-009417-458rrhcm	369	8	of	of	IN
cord-009417-458rrhcm	369	9	transfusion	transfusion	NN
cord-009417-458rrhcm	369	10	but	but	CC
cord-009417-458rrhcm	369	11	increase	increase	NN
cord-009417-458rrhcm	369	12	after	after	IN
cord-009417-458rrhcm	369	13	transfusion	transfusion	NN
cord-009417-458rrhcm	369	14	in	in	IN
cord-009417-458rrhcm	369	15	a	a	DT
cord-009417-458rrhcm	369	16	manner	manner	NN
cord-009417-458rrhcm	369	17	analogous	analogous	JJ
cord-009417-458rrhcm	369	18	to	to	IN
cord-009417-458rrhcm	369	19	the	the	DT
cord-009417-458rrhcm	369	20	vaccination	vaccination	NN
cord-009417-458rrhcm	369	21	"	"	``
cord-009417-458rrhcm	369	22	booster	booster	NN
cord-009417-458rrhcm	369	23	"	"	''
cord-009417-458rrhcm	369	24	effect	effect	NN
cord-009417-458rrhcm	369	25	.	.	.
cord-009417-458rrhcm	370	1	These	these	DT
cord-009417-458rrhcm	370	2	reactions	reaction	NNS
cord-009417-458rrhcm	370	3	typically	typically	RB
cord-009417-458rrhcm	370	4	occur	occur	VBP
cord-009417-458rrhcm	370	5	3	3	CD
cord-009417-458rrhcm	370	6	to	to	TO
cord-009417-458rrhcm	370	7	14	14	CD
cord-009417-458rrhcm	370	8	days	day	NNS
cord-009417-458rrhcm	370	9	after	after	IN
cord-009417-458rrhcm	370	10	transfusion	transfusion	NN
cord-009417-458rrhcm	370	11	but	but	CC
cord-009417-458rrhcm	370	12	are	be	VBP
cord-009417-458rrhcm	370	13	unrecognized	unrecognized	JJ
cord-009417-458rrhcm	370	14	because	because	IN
cord-009417-458rrhcm	370	15	of	of	IN
cord-009417-458rrhcm	370	16	the	the	DT
cord-009417-458rrhcm	370	17	lack	lack	NN
cord-009417-458rrhcm	370	18	of	of	IN
cord-009417-458rrhcm	370	19	a	a	DT
cord-009417-458rrhcm	370	20	clear	clear	JJ
cord-009417-458rrhcm	370	21	temporal	temporal	JJ
cord-009417-458rrhcm	370	22	association	association	NN
cord-009417-458rrhcm	370	23	with	with	IN
cord-009417-458rrhcm	370	24	transfusion	transfusion	NN
cord-009417-458rrhcm	370	25	.	.	.
cord-009417-458rrhcm	371	1	Fever	fever	NN
cord-009417-458rrhcm	371	2	,	,	,
cord-009417-458rrhcm	371	3	chills	chill	NNS
cord-009417-458rrhcm	371	4	,	,	,
cord-009417-458rrhcm	371	5	and	and	CC
cord-009417-458rrhcm	371	6	an	an	DT
cord-009417-458rrhcm	371	7	unexplained	unexplained	JJ
cord-009417-458rrhcm	371	8	decline	decline	NN
cord-009417-458rrhcm	371	9	in	in	IN
cord-009417-458rrhcm	371	10	Hct	Hct	NNP
cord-009417-458rrhcm	371	11	are	be	VBP
cord-009417-458rrhcm	371	12	the	the	DT
cord-009417-458rrhcm	371	13	usual	usual	JJ
cord-009417-458rrhcm	371	14	signs	sign	NNS
cord-009417-458rrhcm	371	15	.	.	.
cord-009417-458rrhcm	372	1	75	75	CD
cord-009417-458rrhcm	372	2	Transient	transient	JJ
cord-009417-458rrhcm	372	3	elevation	elevation	NN
cord-009417-458rrhcm	372	4	in	in	IN
cord-009417-458rrhcm	372	5	bilirubin	bilirubin	NN
cord-009417-458rrhcm	372	6	and	and	CC
cord-009417-458rrhcm	372	7	lactate	lactate	NN
cord-009417-458rrhcm	372	8	dehydrogenase	dehydrogenase	NN
cord-009417-458rrhcm	372	9	may	may	MD
cord-009417-458rrhcm	372	10	also	also	RB
cord-009417-458rrhcm	372	11	occur	occur	VB
cord-009417-458rrhcm	372	12	.	.	.
cord-009417-458rrhcm	373	1	The	the	DT
cord-009417-458rrhcm	373	2	diagnosis	diagnosis	NN
cord-009417-458rrhcm	373	3	is	be	VBZ
cord-009417-458rrhcm	373	4	established	establish	VBN
cord-009417-458rrhcm	373	5	by	by	IN
cord-009417-458rrhcm	373	6	a	a	DT
cord-009417-458rrhcm	373	7	positive	positive	JJ
cord-009417-458rrhcm	373	8	direct	direct	JJ
cord-009417-458rrhcm	373	9	antiglobulin	antiglobulin	NN
cord-009417-458rrhcm	373	10	(	(	-LRB-
cord-009417-458rrhcm	373	11	Coombs	Coombs	NNP
cord-009417-458rrhcm	373	12	)	)	-RRB-
cord-009417-458rrhcm	373	13	test	test	NN
cord-009417-458rrhcm	373	14	resulting	result	VBG
cord-009417-458rrhcm	373	15	from	from	IN
cord-009417-458rrhcm	373	16	recipient	recipient	NN
cord-009417-458rrhcm	373	17	antibody	antibody	NN
cord-009417-458rrhcm	373	18	coating	coating	NN
cord-009417-458rrhcm	373	19	donor	donor	NN
cord-009417-458rrhcm	373	20	RBCs	rbc	NNS
cord-009417-458rrhcm	373	21	.	.	.
cord-009417-458rrhcm	374	1	The	the	DT
cord-009417-458rrhcm	374	2	antibody	antibody	NN
cord-009417-458rrhcm	374	3	may	may	MD
cord-009417-458rrhcm	374	4	be	be	VB
cord-009417-458rrhcm	374	5	identifi	identifi	VBN
cord-009417-458rrhcm	374	6	ed	ed	NNP
cord-009417-458rrhcm	374	7	by	by	IN
cord-009417-458rrhcm	374	8	eluting	elute	VBG
cord-009417-458rrhcm	374	9	it	-PRON-	PRP
cord-009417-458rrhcm	374	10	from	from	IN
cord-009417-458rrhcm	374	11	the	the	DT
cord-009417-458rrhcm	374	12	RBCs	rbc	NNS
cord-009417-458rrhcm	374	13	or	or	CC
cord-009417-458rrhcm	374	14	by	by	IN
cord-009417-458rrhcm	374	15	demonstrating	demonstrate	VBG
cord-009417-458rrhcm	374	16	it	-PRON-	PRP
cord-009417-458rrhcm	374	17	within	within	IN
cord-009417-458rrhcm	374	18	the	the	DT
cord-009417-458rrhcm	374	19	recipient	recipient	NN
cord-009417-458rrhcm	374	20	's	's	POS
cord-009417-458rrhcm	374	21	serum	serum	NN
cord-009417-458rrhcm	374	22	.	.	.
cord-009417-458rrhcm	375	1	The	the	DT
cord-009417-458rrhcm	375	2	specifi	specifi	JJ
cord-009417-458rrhcm	375	3	city	city	NN
cord-009417-458rrhcm	375	4	of	of	IN
cord-009417-458rrhcm	375	5	the	the	DT
cord-009417-458rrhcm	375	6	antibody	antibody	NN
cord-009417-458rrhcm	375	7	is	be	VBZ
cord-009417-458rrhcm	375	8	often	often	RB
cord-009417-458rrhcm	375	9	against	against	IN
cord-009417-458rrhcm	375	10	such	such	JJ
cord-009417-458rrhcm	375	11	RBC	RBC	NNP
cord-009417-458rrhcm	375	12	antigens	antigen	NNS
cord-009417-458rrhcm	375	13	as	as	IN
cord-009417-458rrhcm	375	14	the	the	DT
cord-009417-458rrhcm	375	15	Rh	Rh	NNP
cord-009417-458rrhcm	375	16	family	family	NN
cord-009417-458rrhcm	375	17	,	,	,
cord-009417-458rrhcm	375	18	Kidd	Kidd	NNP
cord-009417-458rrhcm	375	19	,	,	,
cord-009417-458rrhcm	375	20	Duffy	Duffy	NNP
cord-009417-458rrhcm	375	21	,	,	,
cord-009417-458rrhcm	375	22	or	or	CC
cord-009417-458rrhcm	375	23	Kell	Kell	NNP
cord-009417-458rrhcm	375	24	systems	system	NNS
cord-009417-458rrhcm	375	25	.	.	.
cord-009417-458rrhcm	376	1	Hemolysis	Hemolysis	NNP
cord-009417-458rrhcm	376	2	may	may	MD
cord-009417-458rrhcm	376	3	not	not	RB
cord-009417-458rrhcm	376	4	occur	occur	VB
cord-009417-458rrhcm	376	5	,	,	,
cord-009417-458rrhcm	376	6	but	but	CC
cord-009417-458rrhcm	376	7	if	if	IN
cord-009417-458rrhcm	376	8	it	-PRON-	PRP
cord-009417-458rrhcm	376	9	does	do	VBZ
cord-009417-458rrhcm	376	10	,	,	,
cord-009417-458rrhcm	376	11	it	-PRON-	PRP
cord-009417-458rrhcm	376	12	is	be	VBZ
cord-009417-458rrhcm	376	13	likely	likely	JJ
cord-009417-458rrhcm	376	14	to	to	TO
cord-009417-458rrhcm	376	15	be	be	VB
cord-009417-458rrhcm	376	16	extravascular	extravascular	JJ
cord-009417-458rrhcm	376	17	and	and	CC
cord-009417-458rrhcm	376	18	only	only	RB
cord-009417-458rrhcm	376	19	rarely	rarely	RB
cord-009417-458rrhcm	376	20	causes	cause	VBZ
cord-009417-458rrhcm	376	21	renal	renal	JJ
cord-009417-458rrhcm	376	22	failure	failure	NN
cord-009417-458rrhcm	376	23	or	or	CC
cord-009417-458rrhcm	376	24	DIC	DIC	NNP
cord-009417-458rrhcm	376	25	.	.	.
cord-009417-458rrhcm	377	1	Prevention	prevention	NN
cord-009417-458rrhcm	377	2	of	of	IN
cord-009417-458rrhcm	377	3	these	these	DT
cord-009417-458rrhcm	377	4	reactions	reaction	NNS
cord-009417-458rrhcm	377	5	is	be	VBZ
cord-009417-458rrhcm	377	6	diffi	diffi	JJ
cord-009417-458rrhcm	377	7	cult	cult	NN
cord-009417-458rrhcm	377	8	.	.	.
cord-009417-458rrhcm	378	1	Alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	378	2	to	to	IN
cord-009417-458rrhcm	378	3	foreign	foreign	JJ
cord-009417-458rrhcm	378	4	RBC	RBC	NNP
cord-009417-458rrhcm	378	5	antigens	antigen	NNS
cord-009417-458rrhcm	378	6	occurs	occur	VBZ
cord-009417-458rrhcm	378	7	in	in	IN
cord-009417-458rrhcm	378	8	approximately	approximately	RB
cord-009417-458rrhcm	378	9	1	1	CD
cord-009417-458rrhcm	378	10	%	%	NN
cord-009417-458rrhcm	378	11	of	of	IN
cord-009417-458rrhcm	378	12	transfusions	transfusion	NNS
cord-009417-458rrhcm	378	13	.	.	.
cord-009417-458rrhcm	379	1	67	67	CD
cord-009417-458rrhcm	379	2	Detection	detection	NN
cord-009417-458rrhcm	379	3	of	of	IN
cord-009417-458rrhcm	379	4	delayed	delay	VBN
cord-009417-458rrhcm	379	5	antibodies	antibody	NNS
cord-009417-458rrhcm	379	6	is	be	VBZ
cord-009417-458rrhcm	379	7	the	the	DT
cord-009417-458rrhcm	379	8	purpose	purpose	NN
cord-009417-458rrhcm	379	9	for	for	IN
cord-009417-458rrhcm	379	10	requiring	require	VBG
cord-009417-458rrhcm	379	11	a	a	DT
cord-009417-458rrhcm	379	12	new	new	JJ
cord-009417-458rrhcm	379	13	blood	blood	NN
cord-009417-458rrhcm	379	14	bank	bank	NN
cord-009417-458rrhcm	379	15	specimen	specimen	NN
cord-009417-458rrhcm	379	16	every	every	DT
cord-009417-458rrhcm	379	17	72	72	CD
cord-009417-458rrhcm	379	18	hours	hour	NNS
cord-009417-458rrhcm	379	19	if	if	IN
cord-009417-458rrhcm	379	20	the	the	DT
cord-009417-458rrhcm	379	21	patient	patient	NN
cord-009417-458rrhcm	379	22	has	have	VBZ
cord-009417-458rrhcm	379	23	recently	recently	RB
cord-009417-458rrhcm	379	24	been	be	VBN
cord-009417-458rrhcm	379	25	transfused	transfuse	VBN
cord-009417-458rrhcm	379	26	.	.	.
cord-009417-458rrhcm	380	1	Permanent	permanent	JJ
cord-009417-458rrhcm	380	2	transfusion	transfusion	NN
cord-009417-458rrhcm	380	3	records	record	NNS
cord-009417-458rrhcm	380	4	should	should	MD
cord-009417-458rrhcm	380	5	record	record	VB
cord-009417-458rrhcm	380	6	the	the	DT
cord-009417-458rrhcm	380	7	occurrence	occurrence	NN
cord-009417-458rrhcm	380	8	of	of	IN
cord-009417-458rrhcm	380	9	delayed	delay	VBN
cord-009417-458rrhcm	380	10	antibodies	antibody	NNS
cord-009417-458rrhcm	380	11	,	,	,
cord-009417-458rrhcm	380	12	even	even	RB
cord-009417-458rrhcm	380	13	though	though	IN
cord-009417-458rrhcm	380	14	they	-PRON-	PRP
cord-009417-458rrhcm	380	15	may	may	MD
cord-009417-458rrhcm	380	16	not	not	RB
cord-009417-458rrhcm	380	17	be	be	VB
cord-009417-458rrhcm	380	18	apparent	apparent	JJ
cord-009417-458rrhcm	380	19	at	at	IN
cord-009417-458rrhcm	380	20	a	a	DT
cord-009417-458rrhcm	380	21	later	later	JJ
cord-009417-458rrhcm	380	22	crossmatch	crossmatch	NN
cord-009417-458rrhcm	380	23	.	.	.
cord-009417-458rrhcm	381	1	Access	access	NN
cord-009417-458rrhcm	381	2	to	to	IN
cord-009417-458rrhcm	381	3	transfusion	transfusion	NN
cord-009417-458rrhcm	381	4	databases	database	NNS
cord-009417-458rrhcm	381	5	is	be	VBZ
cord-009417-458rrhcm	381	6	critical	critical	JJ
cord-009417-458rrhcm	381	7	for	for	IN
cord-009417-458rrhcm	381	8	the	the	DT
cord-009417-458rrhcm	381	9	care	care	NN
cord-009417-458rrhcm	381	10	of	of	IN
cord-009417-458rrhcm	381	11	patients	patient	NNS
cord-009417-458rrhcm	381	12	with	with	IN
cord-009417-458rrhcm	381	13	a	a	DT
cord-009417-458rrhcm	381	14	past	past	JJ
cord-009417-458rrhcm	381	15	history	history	NN
cord-009417-458rrhcm	381	16	of	of	IN
cord-009417-458rrhcm	381	17	transfusion	transfusion	NN
cord-009417-458rrhcm	381	18	.	.	.
cord-009417-458rrhcm	382	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	382	2	-	-	HYPH
cord-009417-458rrhcm	382	3	related	relate	VBN
cord-009417-458rrhcm	382	4	acute	acute	JJ
cord-009417-458rrhcm	382	5	lung	lung	NN
cord-009417-458rrhcm	382	6	injury	injury	NN
cord-009417-458rrhcm	382	7	(	(	-LRB-
cord-009417-458rrhcm	382	8	TRALI	TRALI	NNP
cord-009417-458rrhcm	382	9	)	)	-RRB-
cord-009417-458rrhcm	382	10	is	be	VBZ
cord-009417-458rrhcm	382	11	an	an	DT
cord-009417-458rrhcm	382	12	uncommon	uncommon	JJ
cord-009417-458rrhcm	382	13	(	(	-LRB-
cord-009417-458rrhcm	382	14	0.02	0.02	CD
cord-009417-458rrhcm	382	15	%	%	NN
cord-009417-458rrhcm	382	16	)	)	-RRB-
cord-009417-458rrhcm	382	17	76	76	CD
cord-009417-458rrhcm	382	18	but	but	CC
cord-009417-458rrhcm	382	19	serious	serious	JJ
cord-009417-458rrhcm	382	20	adverse	adverse	JJ
cord-009417-458rrhcm	382	21	effect	effect	NN
cord-009417-458rrhcm	382	22	of	of	IN
cord-009417-458rrhcm	382	23	transfusion	transfusion	NN
cord-009417-458rrhcm	382	24	that	that	WDT
cord-009417-458rrhcm	382	25	has	have	VBZ
cord-009417-458rrhcm	382	26	only	only	RB
cord-009417-458rrhcm	382	27	recently	recently	RB
cord-009417-458rrhcm	382	28	been	be	VBN
cord-009417-458rrhcm	382	29	gaining	gain	VBG
cord-009417-458rrhcm	382	30	recognition	recognition	NN
cord-009417-458rrhcm	382	31	.	.	.
cord-009417-458rrhcm	383	1	Similar	similar	JJ
cord-009417-458rrhcm	383	2	reactions	reaction	NNS
cord-009417-458rrhcm	383	3	have	have	VBP
cord-009417-458rrhcm	383	4	been	be	VBN
cord-009417-458rrhcm	383	5	called	call	VBN
cord-009417-458rrhcm	383	6	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	383	7	leukoagglutinin	leukoagglutinin	NNP
cord-009417-458rrhcm	383	8	reaction	reaction	NN
cord-009417-458rrhcm	383	9	or	or	CC
cord-009417-458rrhcm	383	10	noncardiogenic	noncardiogenic	JJ
cord-009417-458rrhcm	383	11	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	383	12	edema	edema	NN
cord-009417-458rrhcm	383	13	.	.	.
cord-009417-458rrhcm	384	1	These	these	DT
cord-009417-458rrhcm	384	2	reactions	reaction	NNS
cord-009417-458rrhcm	384	3	consist	consist	VBP
cord-009417-458rrhcm	384	4	of	of	IN
cord-009417-458rrhcm	384	5	acute	acute	JJ
cord-009417-458rrhcm	384	6	respiratory	respiratory	JJ
cord-009417-458rrhcm	384	7	distress	distress	NN
cord-009417-458rrhcm	384	8	syndrome	syndrome	NN
cord-009417-458rrhcm	384	9	(	(	-LRB-
cord-009417-458rrhcm	384	10	ARDS	ARDS	NNP
cord-009417-458rrhcm	384	11	)	)	-RRB-
cord-009417-458rrhcm	384	12	,	,	,
cord-009417-458rrhcm	384	13	which	which	WDT
cord-009417-458rrhcm	384	14	develops	develop	VBZ
cord-009417-458rrhcm	384	15	1	1	CD
cord-009417-458rrhcm	384	16	to	to	TO
cord-009417-458rrhcm	384	17	6	6	CD
cord-009417-458rrhcm	384	18	hours	hour	NNS
cord-009417-458rrhcm	384	19	after	after	IN
cord-009417-458rrhcm	384	20	transfusion	transfusion	NN
cord-009417-458rrhcm	384	21	.	.	.
cord-009417-458rrhcm	385	1	Signs	sign	NNS
cord-009417-458rrhcm	385	2	and	and	CC
cord-009417-458rrhcm	385	3	symptoms	symptom	NNS
cord-009417-458rrhcm	385	4	include	include	VBP
cord-009417-458rrhcm	385	5	bilateral	bilateral	JJ
cord-009417-458rrhcm	385	6	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	385	7	infi	infi	NNP
cord-009417-458rrhcm	385	8	ltrates	ltrates	NNP
cord-009417-458rrhcm	385	9	,	,	,
cord-009417-458rrhcm	385	10	hypoxemia	hypoxemia	NN
cord-009417-458rrhcm	385	11	,	,	,
cord-009417-458rrhcm	385	12	fever	fever	NN
cord-009417-458rrhcm	385	13	,	,	,
cord-009417-458rrhcm	385	14	and	and	CC
cord-009417-458rrhcm	385	15	occasionally	occasionally	RB
cord-009417-458rrhcm	385	16	hypotension	hypotension	NN
cord-009417-458rrhcm	385	17	.	.	.
cord-009417-458rrhcm	386	1	Monitored	monitored	JJ
cord-009417-458rrhcm	386	2	patients	patient	NNS
cord-009417-458rrhcm	386	3	are	be	VBP
cord-009417-458rrhcm	386	4	found	find	VBN
cord-009417-458rrhcm	386	5	to	to	TO
cord-009417-458rrhcm	386	6	have	have	VB
cord-009417-458rrhcm	386	7	normal	normal	JJ
cord-009417-458rrhcm	386	8	or	or	CC
cord-009417-458rrhcm	386	9	low	low	JJ
cord-009417-458rrhcm	386	10	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	386	11	wedge	wedge	NN
cord-009417-458rrhcm	386	12	pressure	pressure	NN
cord-009417-458rrhcm	386	13	and	and	CC
cord-009417-458rrhcm	386	14	central	central	JJ
cord-009417-458rrhcm	386	15	venous	venous	JJ
cord-009417-458rrhcm	386	16	pressure	pressure	NN
cord-009417-458rrhcm	386	17	,	,	,
cord-009417-458rrhcm	386	18	as	as	IN
cord-009417-458rrhcm	386	19	contrasted	contrast	VBN
cord-009417-458rrhcm	386	20	with	with	IN
cord-009417-458rrhcm	386	21	patients	patient	NNS
cord-009417-458rrhcm	386	22	experiencing	experience	VBG
cord-009417-458rrhcm	386	23	volume	volume	NN
cord-009417-458rrhcm	386	24	overload	overload	NN
cord-009417-458rrhcm	386	25	.	.	.
cord-009417-458rrhcm	387	1	If	if	IN
cord-009417-458rrhcm	387	2	adequate	adequate	JJ
cord-009417-458rrhcm	387	3	respiratory	respiratory	JJ
cord-009417-458rrhcm	387	4	support	support	NN
cord-009417-458rrhcm	387	5	and	and	CC
cord-009417-458rrhcm	387	6	oxygenation	oxygenation	NN
cord-009417-458rrhcm	387	7	are	be	VBP
cord-009417-458rrhcm	387	8	established	establish	VBN
cord-009417-458rrhcm	387	9	promptly	promptly	RB
cord-009417-458rrhcm	387	10	,	,	,
cord-009417-458rrhcm	387	11	spontaneous	spontaneous	JJ
cord-009417-458rrhcm	387	12	resolution	resolution	NN
cord-009417-458rrhcm	387	13	generally	generally	RB
cord-009417-458rrhcm	387	14	occurs	occur	VBZ
cord-009417-458rrhcm	387	15	within	within	IN
cord-009417-458rrhcm	387	16	1	1	CD
cord-009417-458rrhcm	387	17	to	to	IN
cord-009417-458rrhcm	387	18	4	4	CD
cord-009417-458rrhcm	387	19	days	day	NNS
cord-009417-458rrhcm	387	20	.	.	.
cord-009417-458rrhcm	388	1	Deaths	death	NNS
cord-009417-458rrhcm	388	2	have	have	VBP
cord-009417-458rrhcm	388	3	nonetheless	nonetheless	RB
cord-009417-458rrhcm	388	4	occurred	occur	VBN
cord-009417-458rrhcm	388	5	,	,	,
cord-009417-458rrhcm	388	6	particularly	particularly	RB
cord-009417-458rrhcm	388	7	with	with	IN
cord-009417-458rrhcm	388	8	a	a	DT
cord-009417-458rrhcm	388	9	delay	delay	NN
cord-009417-458rrhcm	388	10	in	in	IN
cord-009417-458rrhcm	388	11	diagnosis	diagnosis	NN
cord-009417-458rrhcm	388	12	.	.	.
cord-009417-458rrhcm	389	1	77	77	CD
cord-009417-458rrhcm	389	2	,	,	,
cord-009417-458rrhcm	389	3	78	78	CD
cord-009417-458rrhcm	389	4	Episodes	episode	NNS
cord-009417-458rrhcm	389	5	of	of	IN
cord-009417-458rrhcm	389	6	TRALI	TRALI	NNP
cord-009417-458rrhcm	389	7	appear	appear	VBP
cord-009417-458rrhcm	389	8	to	to	TO
cord-009417-458rrhcm	389	9	have	have	VB
cord-009417-458rrhcm	389	10	several	several	JJ
cord-009417-458rrhcm	389	11	possible	possible	JJ
cord-009417-458rrhcm	389	12	causative	causative	JJ
cord-009417-458rrhcm	389	13	mechanisms	mechanism	NNS
cord-009417-458rrhcm	389	14	.	.	.
cord-009417-458rrhcm	390	1	Some	some	DT
cord-009417-458rrhcm	390	2	cases	case	NNS
cord-009417-458rrhcm	390	3	may	may	MD
cord-009417-458rrhcm	390	4	be	be	VB
cord-009417-458rrhcm	390	5	caused	cause	VBN
cord-009417-458rrhcm	390	6	by	by	IN
cord-009417-458rrhcm	390	7	donor	donor	NN
cord-009417-458rrhcm	390	8	antibodies	antibody	NNS
cord-009417-458rrhcm	390	9	reacting	react	VBG
cord-009417-458rrhcm	390	10	with	with	IN
cord-009417-458rrhcm	390	11	recipient	recipient	NN
cord-009417-458rrhcm	390	12	neutrophil	neutrophil	NN
cord-009417-458rrhcm	390	13	or	or	CC
cord-009417-458rrhcm	390	14	HLA	HLA	NNP
cord-009417-458rrhcm	390	15	antigens	antigen	NNS
cord-009417-458rrhcm	390	16	.	.	.
cord-009417-458rrhcm	391	1	79	79	CD
cord-009417-458rrhcm	391	2	Plasma	plasma	NN
cord-009417-458rrhcm	391	3	factors	factor	NNS
cord-009417-458rrhcm	391	4	related	relate	VBN
cord-009417-458rrhcm	391	5	to	to	IN
cord-009417-458rrhcm	391	6	blood	blood	NN
cord-009417-458rrhcm	391	7	storage	storage	NN
cord-009417-458rrhcm	391	8	have	have	VBP
cord-009417-458rrhcm	391	9	also	also	RB
cord-009417-458rrhcm	391	10	been	be	VBN
cord-009417-458rrhcm	391	11	implicated	implicate	VBN
cord-009417-458rrhcm	391	12	,	,	,
cord-009417-458rrhcm	391	13	such	such	JJ
cord-009417-458rrhcm	391	14	as	as	IN
cord-009417-458rrhcm	391	15	lipid	lipid	NN
cord-009417-458rrhcm	391	16	substances	substance	NNS
cord-009417-458rrhcm	391	17	from	from	IN
cord-009417-458rrhcm	391	18	deterioration	deterioration	NN
cord-009417-458rrhcm	391	19	of	of	IN
cord-009417-458rrhcm	391	20	donor	donor	NN
cord-009417-458rrhcm	391	21	cell	cell	NN
cord-009417-458rrhcm	391	22	membranes	membrane	NNS
cord-009417-458rrhcm	391	23	that	that	WDT
cord-009417-458rrhcm	391	24	prime	prime	JJ
cord-009417-458rrhcm	391	25	recipient	recipient	NN
cord-009417-458rrhcm	391	26	neu	neu	NNP
cord-009417-458rrhcm	391	27	-	-	HYPH
cord-009417-458rrhcm	391	28	trophils	trophils	NNP
cord-009417-458rrhcm	391	29	,	,	,
cord-009417-458rrhcm	391	30	which	which	WDT
cord-009417-458rrhcm	391	31	then	then	RB
cord-009417-458rrhcm	391	32	damage	damage	VBP
cord-009417-458rrhcm	391	33	the	the	DT
cord-009417-458rrhcm	391	34	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	391	35	vasculature	vasculature	NN
cord-009417-458rrhcm	391	36	and	and	CC
cord-009417-458rrhcm	391	37	lead	lead	VB
cord-009417-458rrhcm	391	38	to	to	IN
cord-009417-458rrhcm	391	39	increased	increase	VBN
cord-009417-458rrhcm	391	40	capillary	capillary	JJ
cord-009417-458rrhcm	391	41	permeability	permeability	NN
cord-009417-458rrhcm	391	42	and	and	CC
cord-009417-458rrhcm	391	43	an	an	DT
cord-009417-458rrhcm	391	44	ARDSlike	ardslike	NN
cord-009417-458rrhcm	391	45	syndrome	syndrome	NN
cord-009417-458rrhcm	391	46	.	.	.
cord-009417-458rrhcm	392	1	80	80	CD
cord-009417-458rrhcm	392	2	Other	other	JJ
cord-009417-458rrhcm	392	3	clinical	clinical	JJ
cord-009417-458rrhcm	392	4	factors	factor	NNS
cord-009417-458rrhcm	392	5	may	may	MD
cord-009417-458rrhcm	392	6	contribute	contribute	VB
cord-009417-458rrhcm	392	7	to	to	IN
cord-009417-458rrhcm	392	8	increased	increase	VBN
cord-009417-458rrhcm	392	9	risk	risk	NN
cord-009417-458rrhcm	392	10	,	,	,
cord-009417-458rrhcm	392	11	such	such	JJ
cord-009417-458rrhcm	392	12	as	as	IN
cord-009417-458rrhcm	392	13	cardiac	cardiac	JJ
cord-009417-458rrhcm	392	14	bypass	bypass	NN
cord-009417-458rrhcm	392	15	surgery	surgery	NN
cord-009417-458rrhcm	392	16	or	or	CC
cord-009417-458rrhcm	392	17	other	other	JJ
cord-009417-458rrhcm	392	18	procedures	procedure	NNS
cord-009417-458rrhcm	392	19	.	.	.
cord-009417-458rrhcm	393	1	In	in	IN
cord-009417-458rrhcm	393	2	the	the	DT
cord-009417-458rrhcm	393	3	antibody	antibody	NN
cord-009417-458rrhcm	393	4	model	model	NN
cord-009417-458rrhcm	393	5	at	at	IN
cord-009417-458rrhcm	393	6	least	least	JJS
cord-009417-458rrhcm	393	7	,	,	,
cord-009417-458rrhcm	393	8	the	the	DT
cord-009417-458rrhcm	393	9	implicated	implicate	VBN
cord-009417-458rrhcm	393	10	antibody	antibody	NN
cord-009417-458rrhcm	393	11	is	be	VBZ
cord-009417-458rrhcm	393	12	unique	unique	JJ
cord-009417-458rrhcm	393	13	to	to	IN
cord-009417-458rrhcm	393	14	the	the	DT
cord-009417-458rrhcm	393	15	donor	donor	NN
cord-009417-458rrhcm	393	16	and	and	CC
cord-009417-458rrhcm	393	17	the	the	DT
cord-009417-458rrhcm	393	18	affl	affl	NNP
cord-009417-458rrhcm	393	19	icted	icte	VBN
cord-009417-458rrhcm	393	20	recipient	recipient	NN
cord-009417-458rrhcm	393	21	will	will	MD
cord-009417-458rrhcm	393	22	probably	probably	RB
cord-009417-458rrhcm	393	23	not	not	RB
cord-009417-458rrhcm	393	24	experience	experience	VB
cord-009417-458rrhcm	393	25	another	another	DT
cord-009417-458rrhcm	393	26	such	such	JJ
cord-009417-458rrhcm	393	27	reaction	reaction	NN
cord-009417-458rrhcm	393	28	,	,	,
cord-009417-458rrhcm	393	29	provided	provide	VBD
cord-009417-458rrhcm	393	30	that	that	IN
cord-009417-458rrhcm	393	31	the	the	DT
cord-009417-458rrhcm	393	32	recipient	recipient	NN
cord-009417-458rrhcm	393	33	is	be	VBZ
cord-009417-458rrhcm	393	34	not	not	RB
cord-009417-458rrhcm	393	35	exposed	expose	VBN
cord-009417-458rrhcm	393	36	to	to	IN
cord-009417-458rrhcm	393	37	the	the	DT
cord-009417-458rrhcm	393	38	same	same	JJ
cord-009417-458rrhcm	393	39	donor	donor	NN
cord-009417-458rrhcm	393	40	.	.	.
cord-009417-458rrhcm	394	1	TRALI	TRALI	NNP
cord-009417-458rrhcm	394	2	is	be	VBZ
cord-009417-458rrhcm	394	3	undoubtedly	undoubtedly	RB
cord-009417-458rrhcm	394	4	under	under	RB
cord-009417-458rrhcm	394	5	-	-	HYPH
cord-009417-458rrhcm	394	6	recognized	recognize	VBN
cord-009417-458rrhcm	394	7	in	in	IN
cord-009417-458rrhcm	394	8	the	the	DT
cord-009417-458rrhcm	394	9	critical	critical	JJ
cord-009417-458rrhcm	394	10	care	care	NN
cord-009417-458rrhcm	394	11	setting	setting	NN
cord-009417-458rrhcm	394	12	and	and	CC
cord-009417-458rrhcm	394	13	may	may	MD
cord-009417-458rrhcm	394	14	frequently	frequently	RB
cord-009417-458rrhcm	394	15	be	be	VB
cord-009417-458rrhcm	394	16	confused	confuse	VBN
cord-009417-458rrhcm	394	17	with	with	IN
cord-009417-458rrhcm	394	18	fl	fl	NNP
cord-009417-458rrhcm	394	19	uid	uid	NN
cord-009417-458rrhcm	394	20	overload	overload	NN
cord-009417-458rrhcm	394	21	or	or	CC
cord-009417-458rrhcm	394	22	cardiogenic	cardiogenic	JJ
cord-009417-458rrhcm	394	23	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	394	24	edema	edema	NN
cord-009417-458rrhcm	394	25	.	.	.
cord-009417-458rrhcm	395	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	395	2	-	-	HYPH
cord-009417-458rrhcm	395	3	associated	associate	VBN
cord-009417-458rrhcm	395	4	GVHD	GVHD	NNP
cord-009417-458rrhcm	396	1	(	(	-LRB-
cord-009417-458rrhcm	396	2	TA	TA	NNP
cord-009417-458rrhcm	396	3	-	-	HYPH
cord-009417-458rrhcm	396	4	GVHD	GVHD	NNP
cord-009417-458rrhcm	396	5	)	)	-RRB-
cord-009417-458rrhcm	396	6	is	be	VBZ
cord-009417-458rrhcm	396	7	a	a	DT
cord-009417-458rrhcm	396	8	welldocumented	welldocumented	NN
cord-009417-458rrhcm	396	9	,	,	,
cord-009417-458rrhcm	396	10	but	but	CC
cord-009417-458rrhcm	396	11	probably	probably	RB
cord-009417-458rrhcm	396	12	under	under	RB
cord-009417-458rrhcm	396	13	-	-	HYPH
cord-009417-458rrhcm	396	14	recognized	recognize	VBN
cord-009417-458rrhcm	396	15	,	,	,
cord-009417-458rrhcm	396	16	highly	highly	RB
cord-009417-458rrhcm	396	17	lethal	lethal	JJ
cord-009417-458rrhcm	396	18	immunologic	immunologic	JJ
cord-009417-458rrhcm	396	19	complication	complication	NN
cord-009417-458rrhcm	396	20	of	of	IN
cord-009417-458rrhcm	396	21	blood	blood	NN
cord-009417-458rrhcm	396	22	transfusion	transfusion	NN
cord-009417-458rrhcm	396	23	.	.	.
cord-009417-458rrhcm	397	1	81	81	CD
cord-009417-458rrhcm	398	1	Immunocompromised	immunocompromise	VBN
cord-009417-458rrhcm	398	2	patients	patient	NNS
cord-009417-458rrhcm	398	3	infused	infuse	VBN
cord-009417-458rrhcm	398	4	with	with	IN
cord-009417-458rrhcm	398	5	blood	blood	NN
cord-009417-458rrhcm	398	6	components	component	NNS
cord-009417-458rrhcm	398	7	containing	contain	VBG
cord-009417-458rrhcm	398	8	viable	viable	JJ
cord-009417-458rrhcm	398	9	donor	donor	NN
cord-009417-458rrhcm	398	10	lymphocytes	lymphocyte	NNS
cord-009417-458rrhcm	398	11	are	be	VBP
cord-009417-458rrhcm	398	12	at	at	IN
cord-009417-458rrhcm	398	13	risk	risk	NN
cord-009417-458rrhcm	398	14	for	for	IN
cord-009417-458rrhcm	398	15	engraftment	engraftment	NN
cord-009417-458rrhcm	398	16	of	of	IN
cord-009417-458rrhcm	398	17	the	the	DT
cord-009417-458rrhcm	398	18	allogeneic	allogeneic	NN
cord-009417-458rrhcm	398	19	lymphocytes	lymphocyte	NNS
cord-009417-458rrhcm	398	20	and	and	CC
cord-009417-458rrhcm	398	21	ensuing	ensue	VBG
cord-009417-458rrhcm	398	22	rejection	rejection	NN
cord-009417-458rrhcm	398	23	of	of	IN
cord-009417-458rrhcm	398	24	recipient	recipient	NN
cord-009417-458rrhcm	398	25	(	(	-LRB-
cord-009417-458rrhcm	398	26	host	host	NN
cord-009417-458rrhcm	398	27	)	)	-RRB-
cord-009417-458rrhcm	398	28	tissues	tissue	NNS
cord-009417-458rrhcm	398	29	.	.	.
cord-009417-458rrhcm	399	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	399	2	recipients	recipient	NNS
cord-009417-458rrhcm	399	3	who	who	WP
cord-009417-458rrhcm	399	4	are	be	VBP
cord-009417-458rrhcm	399	5	at	at	IN
cord-009417-458rrhcm	399	6	highest	high	JJS
cord-009417-458rrhcm	399	7	risk	risk	NN
cord-009417-458rrhcm	399	8	include	include	VBP
cord-009417-458rrhcm	399	9	neonates	neonate	NNS
cord-009417-458rrhcm	399	10	,	,	,
cord-009417-458rrhcm	399	11	especially	especially	RB
cord-009417-458rrhcm	399	12	the	the	DT
cord-009417-458rrhcm	399	13	very	very	RB
cord-009417-458rrhcm	399	14	premature	premature	JJ
cord-009417-458rrhcm	399	15	,	,	,
cord-009417-458rrhcm	399	16	bone	bone	NN
cord-009417-458rrhcm	399	17	marrow	marrow	NN
cord-009417-458rrhcm	399	18	and	and	CC
cord-009417-458rrhcm	399	19	organ	organ	NN
cord-009417-458rrhcm	399	20	transplant	transplant	NN
cord-009417-458rrhcm	399	21	recipients	recipient	NNS
cord-009417-458rrhcm	399	22	,	,	,
cord-009417-458rrhcm	399	23	and	and	CC
cord-009417-458rrhcm	399	24	leukemia	leukemia	NN
cord-009417-458rrhcm	399	25	and	and	CC
cord-009417-458rrhcm	399	26	lymphoma	lymphoma	NN
cord-009417-458rrhcm	399	27	patients	patient	NNS
cord-009417-458rrhcm	399	28	.	.	.
cord-009417-458rrhcm	400	1	TA	TA	NNP
cord-009417-458rrhcm	400	2	-	-	HYPH
cord-009417-458rrhcm	400	3	GVHD	GVHD	NNP
cord-009417-458rrhcm	400	4	has	have	VBZ
cord-009417-458rrhcm	400	5	also	also	RB
cord-009417-458rrhcm	400	6	been	be	VBN
cord-009417-458rrhcm	400	7	reported	report	VBN
cord-009417-458rrhcm	400	8	in	in	IN
cord-009417-458rrhcm	400	9	patients	patient	NNS
cord-009417-458rrhcm	400	10	after	after	IN
cord-009417-458rrhcm	400	11	cardiac	cardiac	JJ
cord-009417-458rrhcm	400	12	surgery	surgery	NN
cord-009417-458rrhcm	400	13	who	who	WP
cord-009417-458rrhcm	400	14	received	receive	VBD
cord-009417-458rrhcm	400	15	designated	designated	JJ
cord-009417-458rrhcm	400	16	donor	donor	NN
cord-009417-458rrhcm	400	17	blood	blood	NN
cord-009417-458rrhcm	400	18	from	from	IN
cord-009417-458rrhcm	400	19	relatives	relative	NNS
cord-009417-458rrhcm	400	20	;	;	:
cord-009417-458rrhcm	400	21	presumably	presumably	RB
cord-009417-458rrhcm	400	22	,	,	,
cord-009417-458rrhcm	400	23	the	the	DT
cord-009417-458rrhcm	400	24	HLA	HLA	NNP
cord-009417-458rrhcm	400	25	antigenic	antigenic	JJ
cord-009417-458rrhcm	400	26	differences	difference	NNS
cord-009417-458rrhcm	400	27	between	between	IN
cord-009417-458rrhcm	400	28	donor	donor	NN
cord-009417-458rrhcm	400	29	and	and	CC
cord-009417-458rrhcm	400	30	recipient	recipient	NN
cord-009417-458rrhcm	400	31	were	be	VBD
cord-009417-458rrhcm	400	32	insuffi	insuffi	NNP
cord-009417-458rrhcm	400	33	cient	cient	NNP
cord-009417-458rrhcm	400	34	to	to	TO
cord-009417-458rrhcm	400	35	stimulate	stimulate	VB
cord-009417-458rrhcm	400	36	a	a	DT
cord-009417-458rrhcm	400	37	recipient	recipient	NN
cord-009417-458rrhcm	400	38	immune	immune	JJ
cord-009417-458rrhcm	400	39	response	response	NN
cord-009417-458rrhcm	400	40	but	but	CC
cord-009417-458rrhcm	400	41	suffi	suffi	NNP
cord-009417-458rrhcm	400	42	cient	cient	NNP
cord-009417-458rrhcm	400	43	to	to	TO
cord-009417-458rrhcm	400	44	elicit	elicit	VB
cord-009417-458rrhcm	400	45	a	a	DT
cord-009417-458rrhcm	400	46	donor	donor	NN
cord-009417-458rrhcm	400	47	immune	immune	JJ
cord-009417-458rrhcm	400	48	response	response	NN
cord-009417-458rrhcm	400	49	.	.	.
cord-009417-458rrhcm	401	1	82	82	CD
cord-009417-458rrhcm	402	1	The	the	DT
cord-009417-458rrhcm	402	2	onset	onset	NN
cord-009417-458rrhcm	402	3	of	of	IN
cord-009417-458rrhcm	402	4	TA	TA	NNP
cord-009417-458rrhcm	402	5	-	-	HYPH
cord-009417-458rrhcm	402	6	GVHD	GVHD	NNP
cord-009417-458rrhcm	402	7	is	be	VBZ
cord-009417-458rrhcm	402	8	usually	usually	RB
cord-009417-458rrhcm	402	9	within	within	IN
cord-009417-458rrhcm	402	10	8	8	CD
cord-009417-458rrhcm	402	11	to	to	TO
cord-009417-458rrhcm	402	12	30	30	CD
cord-009417-458rrhcm	402	13	days	day	NNS
cord-009417-458rrhcm	402	14	after	after	IN
cord-009417-458rrhcm	402	15	transfusion	transfusion	NN
cord-009417-458rrhcm	402	16	,	,	,
cord-009417-458rrhcm	402	17	and	and	CC
cord-009417-458rrhcm	402	18	it	-PRON-	PRP
cord-009417-458rrhcm	402	19	is	be	VBZ
cord-009417-458rrhcm	402	20	manifested	manifest	VBN
cord-009417-458rrhcm	402	21	as	as	IN
cord-009417-458rrhcm	402	22	fever	fever	NN
cord-009417-458rrhcm	402	23	and	and	CC
cord-009417-458rrhcm	402	24	rash	rash	NN
cord-009417-458rrhcm	402	25	,	,	,
cord-009417-458rrhcm	402	26	followed	follow	VBN
cord-009417-458rrhcm	402	27	by	by	IN
cord-009417-458rrhcm	402	28	diarrhea	diarrhea	NN
cord-009417-458rrhcm	402	29	and	and	CC
cord-009417-458rrhcm	402	30	evidence	evidence	NN
cord-009417-458rrhcm	402	31	of	of	IN
cord-009417-458rrhcm	402	32	liver	liver	NN
cord-009417-458rrhcm	402	33	and	and	CC
cord-009417-458rrhcm	402	34	bone	bone	NN
cord-009417-458rrhcm	402	35	marrow	marrow	NN
cord-009417-458rrhcm	402	36	injury	injury	NN
cord-009417-458rrhcm	402	37	.	.	.
cord-009417-458rrhcm	403	1	TA	TA	NNP
cord-009417-458rrhcm	403	2	-	-	HYPH
cord-009417-458rrhcm	403	3	GVHD	GVHD	NNP
cord-009417-458rrhcm	403	4	differs	differ	VBZ
cord-009417-458rrhcm	403	5	from	from	IN
cord-009417-458rrhcm	403	6	that	that	DT
cord-009417-458rrhcm	403	7	seen	see	VBN
cord-009417-458rrhcm	403	8	in	in	IN
cord-009417-458rrhcm	403	9	bone	bone	NN
cord-009417-458rrhcm	403	10	marrow	marrow	NN
cord-009417-458rrhcm	403	11	transplantation	transplantation	NN
cord-009417-458rrhcm	403	12	(	(	-LRB-
cord-009417-458rrhcm	403	13	BMT	BMT	NNP
cord-009417-458rrhcm	403	14	)	)	-RRB-
cord-009417-458rrhcm	403	15	by	by	IN
cord-009417-458rrhcm	403	16	its	-PRON-	PRP$
cord-009417-458rrhcm	403	17	involvement	involvement	NN
cord-009417-458rrhcm	403	18	of	of	IN
cord-009417-458rrhcm	403	19	the	the	DT
cord-009417-458rrhcm	403	20	marrow	marrow	NN
cord-009417-458rrhcm	403	21	and	and	CC
cord-009417-458rrhcm	403	22	by	by	IN
cord-009417-458rrhcm	403	23	far	far	RB
cord-009417-458rrhcm	403	24	greater	great	JJR
cord-009417-458rrhcm	403	25	mortality	mortality	NN
cord-009417-458rrhcm	403	26	.	.	.
cord-009417-458rrhcm	404	1	Treatment	treatment	NN
cord-009417-458rrhcm	404	2	is	be	VBZ
cord-009417-458rrhcm	404	3	largely	largely	RB
cord-009417-458rrhcm	404	4	ineffective	ineffective	JJ
cord-009417-458rrhcm	404	5	,	,	,
cord-009417-458rrhcm	404	6	and	and	CC
cord-009417-458rrhcm	404	7	mortality	mortality	NN
cord-009417-458rrhcm	404	8	exceeds	exceed	VBZ
cord-009417-458rrhcm	404	9	90	90	CD
cord-009417-458rrhcm	404	10	%	%	NN
cord-009417-458rrhcm	404	11	.	.	.
cord-009417-458rrhcm	405	1	Irradiation	irradiation	NN
cord-009417-458rrhcm	405	2	of	of	IN
cord-009417-458rrhcm	405	3	blood	blood	NN
cord-009417-458rrhcm	405	4	components	component	NNS
cord-009417-458rrhcm	405	5	at	at	IN
cord-009417-458rrhcm	405	6	25	25	CD
cord-009417-458rrhcm	405	7	Gy	Gy	NNP
cord-009417-458rrhcm	405	8	prevents	prevent	VBZ
cord-009417-458rrhcm	405	9	TA	TA	NNP
cord-009417-458rrhcm	405	10	-	-	HYPH
cord-009417-458rrhcm	405	11	GVHD	GVHD	NNP
cord-009417-458rrhcm	405	12	by	by	IN
cord-009417-458rrhcm	405	13	eliminating	eliminate	VBG
cord-009417-458rrhcm	405	14	the	the	DT
cord-009417-458rrhcm	405	15	donor	donor	NN
cord-009417-458rrhcm	405	16	lymphocyte	lymphocyte	NN
cord-009417-458rrhcm	405	17	mitogenic	mitogenic	NNP
cord-009417-458rrhcm	405	18	response	response	NN
cord-009417-458rrhcm	405	19	.	.	.
cord-009417-458rrhcm	406	1	All	all	DT
cord-009417-458rrhcm	406	2	cellular	cellular	JJ
cord-009417-458rrhcm	406	3	blood	blood	NN
cord-009417-458rrhcm	406	4	components	component	NNS
cord-009417-458rrhcm	406	5	should	should	MD
cord-009417-458rrhcm	406	6	be	be	VB
cord-009417-458rrhcm	406	7	irradiated	irradiate	VBN
cord-009417-458rrhcm	406	8	before	before	IN
cord-009417-458rrhcm	406	9	transfusion	transfusion	NN
cord-009417-458rrhcm	406	10	to	to	IN
cord-009417-458rrhcm	406	11	high	high	JJ
cord-009417-458rrhcm	406	12	-	-	HYPH
cord-009417-458rrhcm	406	13	risk	risk	NN
cord-009417-458rrhcm	406	14	patients	patient	NNS
cord-009417-458rrhcm	406	15	.	.	.
cord-009417-458rrhcm	407	1	The	the	DT
cord-009417-458rrhcm	407	2	functions	function	NNS
cord-009417-458rrhcm	407	3	of	of	IN
cord-009417-458rrhcm	407	4	the	the	DT
cord-009417-458rrhcm	407	5	cellular	cellular	JJ
cord-009417-458rrhcm	407	6	components	component	NNS
cord-009417-458rrhcm	407	7	of	of	IN
cord-009417-458rrhcm	407	8	blood	blood	NN
cord-009417-458rrhcm	407	9	are	be	VBP
cord-009417-458rrhcm	407	10	unaffected	unaffected	JJ
cord-009417-458rrhcm	407	11	,	,	,
cord-009417-458rrhcm	407	12	although	although	IN
cord-009417-458rrhcm	407	13	damage	damage	NN
cord-009417-458rrhcm	407	14	to	to	IN
cord-009417-458rrhcm	407	15	RBC	RBC	NNP
cord-009417-458rrhcm	407	16	membranes	membrane	NNS
cord-009417-458rrhcm	407	17	limits	limit	NNS
cord-009417-458rrhcm	407	18	postirradiation	postirradiation	NN
cord-009417-458rrhcm	407	19	storage	storage	NN
cord-009417-458rrhcm	407	20	of	of	IN
cord-009417-458rrhcm	407	21	PRBCs	prbc	NNS
cord-009417-458rrhcm	407	22	.	.	.
cord-009417-458rrhcm	408	1	83	83	CD
cord-009417-458rrhcm	408	2	Blood	blood	NN
cord-009417-458rrhcm	408	3	donated	donate	VBN
cord-009417-458rrhcm	408	4	by	by	IN
cord-009417-458rrhcm	408	5	a	a	DT
cord-009417-458rrhcm	408	6	relative	relative	NN
cord-009417-458rrhcm	408	7	for	for	IN
cord-009417-458rrhcm	408	8	any	any	DT
cord-009417-458rrhcm	408	9	patient	patient	NN
cord-009417-458rrhcm	408	10	should	should	MD
cord-009417-458rrhcm	408	11	be	be	VB
cord-009417-458rrhcm	408	12	irradiated	irradiate	VBN
cord-009417-458rrhcm	408	13	,	,	,
cord-009417-458rrhcm	408	14	as	as	IN
cord-009417-458rrhcm	408	15	should	should	MD
cord-009417-458rrhcm	408	16	HLA	HLA	NNP
cord-009417-458rrhcm	408	17	-	-	HYPH
cord-009417-458rrhcm	408	18	matched	match	VBN
cord-009417-458rrhcm	408	19	or	or	CC
cord-009417-458rrhcm	408	20	crossmatched	crossmatched	JJ
cord-009417-458rrhcm	408	21	platelet	platelet	NN
cord-009417-458rrhcm	408	22	products	product	NNS
cord-009417-458rrhcm	408	23	.	.	.
cord-009417-458rrhcm	409	1	Allogeneic	allogeneic	IN
cord-009417-458rrhcm	409	2	blood	blood	NN
cord-009417-458rrhcm	409	3	transfusion	transfusion	NN
cord-009417-458rrhcm	409	4	has	have	VBZ
cord-009417-458rrhcm	409	5	been	be	VBN
cord-009417-458rrhcm	409	6	shown	show	VBN
cord-009417-458rrhcm	409	7	to	to	TO
cord-009417-458rrhcm	409	8	modulate	modulate	VB
cord-009417-458rrhcm	409	9	and	and	CC
cord-009417-458rrhcm	409	10	suppress	suppress	VB
cord-009417-458rrhcm	409	11	the	the	DT
cord-009417-458rrhcm	409	12	recipient	recipient	NN
cord-009417-458rrhcm	409	13	's	's	POS
cord-009417-458rrhcm	409	14	immune	immune	JJ
cord-009417-458rrhcm	409	15	response	response	NN
cord-009417-458rrhcm	409	16	,	,	,
cord-009417-458rrhcm	409	17	an	an	DT
cord-009417-458rrhcm	409	18	effect	effect	NN
cord-009417-458rrhcm	409	19	fi	fi	NN
cord-009417-458rrhcm	409	20	rst	rst	NNP
cord-009417-458rrhcm	409	21	noted	note	VBN
cord-009417-458rrhcm	409	22	with	with	IN
cord-009417-458rrhcm	409	23	kidney	kidney	NN
cord-009417-458rrhcm	409	24	transplantation	transplantation	NN
cord-009417-458rrhcm	409	25	.	.	.
cord-009417-458rrhcm	410	1	84	84	CD
cord-009417-458rrhcm	410	2	Immunosuppression	Immunosuppression	NNP
cord-009417-458rrhcm	410	3	in	in	IN
cord-009417-458rrhcm	410	4	a	a	DT
cord-009417-458rrhcm	410	5	critical	critical	JJ
cord-009417-458rrhcm	410	6	care	care	NN
cord-009417-458rrhcm	410	7	setting	setting	NN
cord-009417-458rrhcm	410	8	is	be	VBZ
cord-009417-458rrhcm	410	9	generally	generally	RB
cord-009417-458rrhcm	410	10	undesirable	undesirable	JJ
cord-009417-458rrhcm	410	11	,	,	,
cord-009417-458rrhcm	410	12	but	but	CC
cord-009417-458rrhcm	410	13	whether	whether	IN
cord-009417-458rrhcm	410	14	transfusion	transfusion	NN
cord-009417-458rrhcm	410	15	has	have	VBZ
cord-009417-458rrhcm	410	16	a	a	DT
cord-009417-458rrhcm	410	17	signifi	signifi	NN
cord-009417-458rrhcm	410	18	ca	can	MD
cord-009417-458rrhcm	410	19	nt	not	RB
cord-009417-458rrhcm	410	20	impact	impact	NN
cord-009417-458rrhcm	410	21	is	be	VBZ
cord-009417-458rrhcm	410	22	debated	debate	VBN
cord-009417-458rrhcm	410	23	.	.	.
cord-009417-458rrhcm	411	1	Ongoing	ongoing	JJ
cord-009417-458rrhcm	411	2	clinical	clinical	JJ
cord-009417-458rrhcm	411	3	issues	issue	NNS
cord-009417-458rrhcm	411	4	center	center	VBP
cord-009417-458rrhcm	411	5	around	around	RB
cord-009417-458rrhcm	411	6	two	two	CD
cord-009417-458rrhcm	411	7	areas	area	NNS
cord-009417-458rrhcm	411	8	of	of	IN
cord-009417-458rrhcm	411	9	controversy	controversy	NN
cord-009417-458rrhcm	411	10	:	:	:
cord-009417-458rrhcm	411	11	the	the	DT
cord-009417-458rrhcm	411	12	putative	putative	JJ
cord-009417-458rrhcm	411	13	association	association	NN
cord-009417-458rrhcm	411	14	between	between	IN
cord-009417-458rrhcm	411	15	blood	blood	NN
cord-009417-458rrhcm	411	16	transfusion	transfusion	NN
cord-009417-458rrhcm	411	17	and	and	CC
cord-009417-458rrhcm	411	18	increased	increase	VBN
cord-009417-458rrhcm	411	19	numbers	number	NNS
cord-009417-458rrhcm	411	20	of	of	IN
cord-009417-458rrhcm	411	21	postoperative	postoperative	JJ
cord-009417-458rrhcm	411	22	infections	infection	NNS
cord-009417-458rrhcm	411	23	and	and	CC
cord-009417-458rrhcm	411	24	increased	increase	VBN
cord-009417-458rrhcm	411	25	and	and	CC
cord-009417-458rrhcm	411	26	more	more	JJR
cord-009417-458rrhcm	411	27	rapid	rapid	JJ
cord-009417-458rrhcm	411	28	rates	rate	NNS
cord-009417-458rrhcm	411	29	of	of	IN
cord-009417-458rrhcm	411	30	tumor	tumor	NN
cord-009417-458rrhcm	411	31	recurrence	recurrence	NN
cord-009417-458rrhcm	411	32	in	in	IN
cord-009417-458rrhcm	411	33	surgical	surgical	JJ
cord-009417-458rrhcm	411	34	oncology	oncology	NN
cord-009417-458rrhcm	411	35	patients	patient	NNS
cord-009417-458rrhcm	411	36	with	with	IN
cord-009417-458rrhcm	411	37	certain	certain	JJ
cord-009417-458rrhcm	411	38	malignancies	malignancy	NNS
cord-009417-458rrhcm	411	39	.	.	.
cord-009417-458rrhcm	412	1	There	there	EX
cord-009417-458rrhcm	412	2	has	have	VBZ
cord-009417-458rrhcm	412	3	been	be	VBN
cord-009417-458rrhcm	412	4	no	no	DT
cord-009417-458rrhcm	412	5	resolution	resolution	NN
cord-009417-458rrhcm	412	6	of	of	IN
cord-009417-458rrhcm	412	7	either	either	DT
cord-009417-458rrhcm	412	8	issue	issue	NN
cord-009417-458rrhcm	412	9	despite	despite	IN
cord-009417-458rrhcm	412	10	a	a	DT
cord-009417-458rrhcm	412	11	few	few	JJ
cord-009417-458rrhcm	412	12	prospective	prospective	JJ
cord-009417-458rrhcm	412	13	trials	trial	NNS
cord-009417-458rrhcm	412	14	having	have	VBG
cord-009417-458rrhcm	412	15	been	be	VBN
cord-009417-458rrhcm	412	16	performed	perform	VBN
cord-009417-458rrhcm	412	17	.	.	.
cord-009417-458rrhcm	413	1	The	the	DT
cord-009417-458rrhcm	413	2	largest	large	JJS
cord-009417-458rrhcm	413	3	pro	pro	JJ
cord-009417-458rrhcm	413	4	-	-	JJ
cord-009417-458rrhcm	413	5	spective	spective	JJ
cord-009417-458rrhcm	413	6	trial	trial	NN
cord-009417-458rrhcm	413	7	of	of	IN
cord-009417-458rrhcm	413	8	colorectal	colorectal	JJ
cord-009417-458rrhcm	413	9	cancer	cancer	NN
cord-009417-458rrhcm	413	10	resection	resection	NN
cord-009417-458rrhcm	413	11	,	,	,
cord-009417-458rrhcm	413	12	for	for	IN
cord-009417-458rrhcm	413	13	example	example	NN
cord-009417-458rrhcm	413	14	,	,	,
cord-009417-458rrhcm	413	15	is	be	VBZ
cord-009417-458rrhcm	413	16	negative	negative	JJ
cord-009417-458rrhcm	413	17	,	,	,
cord-009417-458rrhcm	413	18	85	85	CD
cord-009417-458rrhcm	413	19	but	but	CC
cord-009417-458rrhcm	413	20	a	a	DT
cord-009417-458rrhcm	413	21	meta	meta	JJ
cord-009417-458rrhcm	413	22	-	-	HYPH
cord-009417-458rrhcm	413	23	analysis	analysis	NN
cord-009417-458rrhcm	413	24	of	of	IN
cord-009417-458rrhcm	413	25	the	the	DT
cord-009417-458rrhcm	413	26	extant	extant	JJ
cord-009417-458rrhcm	413	27	data	data	NN
cord-009417-458rrhcm	413	28	suggests	suggest	VBZ
cord-009417-458rrhcm	413	29	that	that	IN
cord-009417-458rrhcm	413	30	an	an	DT
cord-009417-458rrhcm	413	31	adverse	adverse	JJ
cord-009417-458rrhcm	413	32	effect	effect	NN
cord-009417-458rrhcm	413	33	on	on	IN
cord-009417-458rrhcm	413	34	recurrence	recurrence	NN
cord-009417-458rrhcm	413	35	does	do	VBZ
cord-009417-458rrhcm	413	36	exist	exist	VB
cord-009417-458rrhcm	413	37	.	.	.
cord-009417-458rrhcm	414	1	86	86	CD
cord-009417-458rrhcm	415	1	Similarly	similarly	RB
cord-009417-458rrhcm	415	2	,	,	,
cord-009417-458rrhcm	415	3	most	most	JJS
cord-009417-458rrhcm	415	4	of	of	IN
cord-009417-458rrhcm	415	5	the	the	DT
cord-009417-458rrhcm	415	6	randomized	randomized	JJ
cord-009417-458rrhcm	415	7	trials	trial	NNS
cord-009417-458rrhcm	415	8	of	of	IN
cord-009417-458rrhcm	415	9	postoperative	postoperative	JJ
cord-009417-458rrhcm	415	10	or	or	CC
cord-009417-458rrhcm	415	11	critical	critical	JJ
cord-009417-458rrhcm	415	12	care	care	NN
cord-009417-458rrhcm	415	13	unit	unit	NN
cord-009417-458rrhcm	415	14	infections	infection	NNS
cord-009417-458rrhcm	415	15	are	be	VBP
cord-009417-458rrhcm	415	16	too	too	RB
cord-009417-458rrhcm	415	17	small	small	JJ
cord-009417-458rrhcm	415	18	to	to	TO
cord-009417-458rrhcm	415	19	indicate	indicate	VB
cord-009417-458rrhcm	415	20	an	an	DT
cord-009417-458rrhcm	415	21	effect	effect	NN
cord-009417-458rrhcm	415	22	of	of	IN
cord-009417-458rrhcm	415	23	transfusion	transfusion	NN
cord-009417-458rrhcm	415	24	,	,	,
cord-009417-458rrhcm	415	25	but	but	CC
cord-009417-458rrhcm	415	26	all	all	DT
cord-009417-458rrhcm	415	27	point	point	NN
cord-009417-458rrhcm	415	28	in	in	IN
cord-009417-458rrhcm	415	29	the	the	DT
cord-009417-458rrhcm	415	30	direction	direction	NN
cord-009417-458rrhcm	415	31	of	of	IN
cord-009417-458rrhcm	415	32	an	an	DT
cord-009417-458rrhcm	415	33	adverse	adverse	JJ
cord-009417-458rrhcm	415	34	effect	effect	NN
cord-009417-458rrhcm	415	35	.	.	.
cord-009417-458rrhcm	416	1	87	87	CD
cord-009417-458rrhcm	416	2	,	,	,
cord-009417-458rrhcm	416	3	88	88	CD
cord-009417-458rrhcm	416	4	Controversy	controversy	NN
cord-009417-458rrhcm	416	5	will	will	MD
cord-009417-458rrhcm	416	6	continue	continue	VB
cord-009417-458rrhcm	416	7	until	until	IN
cord-009417-458rrhcm	416	8	larger	large	JJR
cord-009417-458rrhcm	416	9	randomized	randomized	JJ
cord-009417-458rrhcm	416	10	trials	trial	NNS
cord-009417-458rrhcm	416	11	are	be	VBP
cord-009417-458rrhcm	416	12	conducted	conduct	VBN
cord-009417-458rrhcm	416	13	.	.	.
cord-009417-458rrhcm	417	1	The	the	DT
cord-009417-458rrhcm	417	2	precise	precise	JJ
cord-009417-458rrhcm	417	3	mechanism	mechanism	NN
cord-009417-458rrhcm	417	4	of	of	IN
cord-009417-458rrhcm	417	5	the	the	DT
cord-009417-458rrhcm	417	6	immunosuppression	immunosuppression	NN
cord-009417-458rrhcm	417	7	induced	induce	VBN
cord-009417-458rrhcm	417	8	by	by	IN
cord-009417-458rrhcm	417	9	allogeneic	allogeneic	NN
cord-009417-458rrhcm	417	10	transfusion	transfusion	NN
cord-009417-458rrhcm	417	11	has	have	VBZ
cord-009417-458rrhcm	417	12	not	not	RB
cord-009417-458rrhcm	417	13	yet	yet	RB
cord-009417-458rrhcm	417	14	been	be	VBN
cord-009417-458rrhcm	417	15	delineated	delineate	VBN
cord-009417-458rrhcm	417	16	,	,	,
cord-009417-458rrhcm	417	17	and	and	CC
cord-009417-458rrhcm	417	18	several	several	JJ
cord-009417-458rrhcm	417	19	mechanisms	mechanism	NNS
cord-009417-458rrhcm	417	20	may	may	MD
cord-009417-458rrhcm	417	21	be	be	VB
cord-009417-458rrhcm	417	22	involved	involve	VBN
cord-009417-458rrhcm	417	23	.	.	.
cord-009417-458rrhcm	418	1	89	89	CD
cord-009417-458rrhcm	418	2	Alterations	alteration	NNS
cord-009417-458rrhcm	418	3	identifi	identifi	NNP
cord-009417-458rrhcm	418	4	ed	ed	NN
cord-009417-458rrhcm	418	5	in	in	RP
cord-009417-458rrhcm	419	1	laboratory	laboratory	NN
cord-009417-458rrhcm	419	2	and	and	CC
cord-009417-458rrhcm	419	3	clinical	clinical	JJ
cord-009417-458rrhcm	419	4	transfusion	transfusion	NN
cord-009417-458rrhcm	419	5	recipients	recipient	NNS
cord-009417-458rrhcm	419	6	have	have	VBP
cord-009417-458rrhcm	419	7	included	include	VBN
cord-009417-458rrhcm	419	8	depression	depression	NN
cord-009417-458rrhcm	419	9	of	of	IN
cord-009417-458rrhcm	419	10	the	the	DT
cord-009417-458rrhcm	419	11	T	T	NNP
cord-009417-458rrhcm	419	12	-	-	HYPH
cord-009417-458rrhcm	419	13	helper/	helper/	NNP
cord-009417-458rrhcm	420	1	Tsuppressor	Tsuppressor	NNP
cord-009417-458rrhcm	420	2	lymphocyte	lymphocyte	NN
cord-009417-458rrhcm	420	3	ratio	ratio	NN
cord-009417-458rrhcm	420	4	,	,	,
cord-009417-458rrhcm	420	5	decreased	decrease	VBD
cord-009417-458rrhcm	420	6	natural	natural	JJ
cord-009417-458rrhcm	420	7	killer	killer	NN
cord-009417-458rrhcm	420	8	cell	cell	NN
cord-009417-458rrhcm	420	9	activity	activity	NN
cord-009417-458rrhcm	420	10	,	,	,
cord-009417-458rrhcm	420	11	diminished	diminish	VBN
cord-009417-458rrhcm	420	12	interleukin-2	interleukin-2	IN
cord-009417-458rrhcm	420	13	generation	generation	NN
cord-009417-458rrhcm	420	14	,	,	,
cord-009417-458rrhcm	420	15	formation	formation	NN
cord-009417-458rrhcm	420	16	of	of	IN
cord-009417-458rrhcm	420	17	anti	anti	JJ
cord-009417-458rrhcm	420	18	-	-	JJ
cord-009417-458rrhcm	420	19	idiotype	idiotype	JJ
cord-009417-458rrhcm	420	20	antibodies	antibody	NNS
cord-009417-458rrhcm	420	21	,	,	,
cord-009417-458rrhcm	420	22	impairment	impairment	NN
cord-009417-458rrhcm	420	23	of	of	IN
cord-009417-458rrhcm	420	24	phagocytic	phagocytic	JJ
cord-009417-458rrhcm	420	25	cell	cell	NN
cord-009417-458rrhcm	420	26	function	function	NN
cord-009417-458rrhcm	420	27	,	,	,
cord-009417-458rrhcm	420	28	and	and	CC
cord-009417-458rrhcm	420	29	chronic	chronic	JJ
cord-009417-458rrhcm	420	30	persistence	persistence	NN
cord-009417-458rrhcm	420	31	of	of	IN
cord-009417-458rrhcm	420	32	donor	donor	NN
cord-009417-458rrhcm	420	33	lymphocytes	lymphocyte	NNS
cord-009417-458rrhcm	420	34	(	(	-LRB-
cord-009417-458rrhcm	420	35	microchimerism	microchimerism	NNP
cord-009417-458rrhcm	420	36	)	)	-RRB-
cord-009417-458rrhcm	420	37	,	,	,
cord-009417-458rrhcm	420	38	suggestive	suggestive	JJ
cord-009417-458rrhcm	420	39	of	of	IN
cord-009417-458rrhcm	420	40	low	low	JJ
cord-009417-458rrhcm	420	41	-	-	HYPH
cord-009417-458rrhcm	420	42	level	level	NN
cord-009417-458rrhcm	420	43	GVHD	GVHD	NNP
cord-009417-458rrhcm	420	44	.	.	.
cord-009417-458rrhcm	421	1	Difficulties	difficulty	NNS
cord-009417-458rrhcm	421	2	in	in	IN
cord-009417-458rrhcm	421	3	analysis	analysis	NN
cord-009417-458rrhcm	421	4	of	of	IN
cord-009417-458rrhcm	421	5	human	human	JJ
cord-009417-458rrhcm	421	6	data	datum	NNS
cord-009417-458rrhcm	421	7	arise	arise	VBP
cord-009417-458rrhcm	421	8	because	because	IN
cord-009417-458rrhcm	421	9	patients	patient	NNS
cord-009417-458rrhcm	421	10	requiring	require	VBG
cord-009417-458rrhcm	421	11	blood	blood	NN
cord-009417-458rrhcm	421	12	transfusions	transfusion	NNS
cord-009417-458rrhcm	421	13	have	have	VBP
cord-009417-458rrhcm	421	14	conditions	condition	NNS
cord-009417-458rrhcm	421	15	that	that	WDT
cord-009417-458rrhcm	421	16	themselves	-PRON-	PRP
cord-009417-458rrhcm	421	17	induce	induce	VBP
cord-009417-458rrhcm	421	18	immune	immune	JJ
cord-009417-458rrhcm	421	19	changes	change	NNS
cord-009417-458rrhcm	421	20	.	.	.
cord-009417-458rrhcm	422	1	There	there	EX
cord-009417-458rrhcm	422	2	is	be	VBZ
cord-009417-458rrhcm	422	3	some	some	DT
cord-009417-458rrhcm	422	4	evidence	evidence	NN
cord-009417-458rrhcm	422	5	,	,	,
cord-009417-458rrhcm	422	6	bolstered	bolster	VBN
cord-009417-458rrhcm	422	7	by	by	IN
cord-009417-458rrhcm	422	8	the	the	DT
cord-009417-458rrhcm	422	9	results	result	NNS
cord-009417-458rrhcm	422	10	of	of	IN
cord-009417-458rrhcm	422	11	two	two	CD
cord-009417-458rrhcm	422	12	large	large	JJ
cord-009417-458rrhcm	422	13	clinical	clinical	JJ
cord-009417-458rrhcm	422	14	trials	trial	NNS
cord-009417-458rrhcm	422	15	,	,	,
cord-009417-458rrhcm	422	16	to	to	TO
cord-009417-458rrhcm	422	17	suggest	suggest	VB
cord-009417-458rrhcm	422	18	that	that	IN
cord-009417-458rrhcm	422	19	leukocyte	leukocyte	NN
cord-009417-458rrhcm	422	20	reduction	reduction	NN
cord-009417-458rrhcm	422	21	of	of	IN
cord-009417-458rrhcm	422	22	blood	blood	NN
cord-009417-458rrhcm	422	23	components	component	NNS
cord-009417-458rrhcm	422	24	reduces	reduce	VBZ
cord-009417-458rrhcm	422	25	or	or	CC
cord-009417-458rrhcm	422	26	eliminates	eliminate	VBZ
cord-009417-458rrhcm	422	27	this	this	DT
cord-009417-458rrhcm	422	28	immunosuppressive	immunosuppressive	JJ
cord-009417-458rrhcm	422	29	effect	effect	NN
cord-009417-458rrhcm	422	30	.	.	.
cord-009417-458rrhcm	423	1	90	90	CD
cord-009417-458rrhcm	423	2	Proponents	proponent	NNS
cord-009417-458rrhcm	423	3	of	of	IN
cord-009417-458rrhcm	423	4	this	this	DT
cord-009417-458rrhcm	423	5	viewpoint	viewpoint	NN
cord-009417-458rrhcm	423	6	argue	argue	VBP
cord-009417-458rrhcm	423	7	that	that	IN
cord-009417-458rrhcm	423	8	for	for	IN
cord-009417-458rrhcm	423	9	this	this	DT
cord-009417-458rrhcm	423	10	reason	reason	NN
cord-009417-458rrhcm	423	11	,	,	,
cord-009417-458rrhcm	423	12	ULR	ULR	NNP
cord-009417-458rrhcm	423	13	would	would	MD
cord-009417-458rrhcm	423	14	benefi	benefi	VB
cord-009417-458rrhcm	423	15	t	t	NNP
cord-009417-458rrhcm	423	16	most	most	JJS
cord-009417-458rrhcm	423	17	patients	patient	NNS
cord-009417-458rrhcm	423	18	receiving	receive	VBG
cord-009417-458rrhcm	423	19	blood	blood	NN
cord-009417-458rrhcm	423	20	transfusions	transfusion	NNS
cord-009417-458rrhcm	423	21	and	and	CC
cord-009417-458rrhcm	423	22	lead	lead	VB
cord-009417-458rrhcm	423	23	to	to	IN
cord-009417-458rrhcm	423	24	fewer	few	JJR
cord-009417-458rrhcm	423	25	infections	infection	NNS
cord-009417-458rrhcm	423	26	,	,	,
cord-009417-458rrhcm	423	27	tumor	tumor	NN
cord-009417-458rrhcm	423	28	recurrences	recurrence	NNS
cord-009417-458rrhcm	423	29	,	,	,
cord-009417-458rrhcm	423	30	and	and	CC
cord-009417-458rrhcm	423	31	other	other	JJ
cord-009417-458rrhcm	423	32	related	relate	VBN
cord-009417-458rrhcm	423	33	putative	putative	JJ
cord-009417-458rrhcm	423	34	risks	risk	NNS
cord-009417-458rrhcm	423	35	of	of	IN
cord-009417-458rrhcm	423	36	transfusion	transfusion	NN
cord-009417-458rrhcm	423	37	,	,	,
cord-009417-458rrhcm	423	38	all	all	DT
cord-009417-458rrhcm	423	39	potentially	potentially	RB
cord-009417-458rrhcm	423	40	resulting	result	VBG
cord-009417-458rrhcm	423	41	in	in	IN
cord-009417-458rrhcm	423	42	saving	save	VBG
cord-009417-458rrhcm	423	43	lives	life	NNS
cord-009417-458rrhcm	423	44	and	and	CC
cord-009417-458rrhcm	423	45	cost	cost	NN
cord-009417-458rrhcm	423	46	.	.	.
cord-009417-458rrhcm	424	1	Prospective	prospective	JJ
cord-009417-458rrhcm	424	2	trials	trial	NNS
cord-009417-458rrhcm	424	3	will	will	MD
cord-009417-458rrhcm	424	4	be	be	VB
cord-009417-458rrhcm	424	5	extremely	extremely	RB
cord-009417-458rrhcm	424	6	important	important	JJ
cord-009417-458rrhcm	424	7	.	.	.
cord-009417-458rrhcm	425	1	91	91	CD
cord-009417-458rrhcm	425	2	Public	public	JJ
cord-009417-458rrhcm	425	3	awareness	awareness	NN
cord-009417-458rrhcm	425	4	of	of	IN
cord-009417-458rrhcm	425	5	transfusion	transfusion	NN
cord-009417-458rrhcm	425	6	-	-	HYPH
cord-009417-458rrhcm	425	7	associated	associate	VBN
cord-009417-458rrhcm	425	8	acquired	acquire	VBD
cord-009417-458rrhcm	426	1	immunodefi	immunodefi	NNP
cord-009417-458rrhcm	426	2	ciency	ciency	NNP
cord-009417-458rrhcm	426	3	syndrome	syndrome	NNP
cord-009417-458rrhcm	426	4	(	(	-LRB-
cord-009417-458rrhcm	426	5	AIDS	AIDS	NNP
cord-009417-458rrhcm	426	6	)	)	-RRB-
cord-009417-458rrhcm	426	7	has	have	VBZ
cord-009417-458rrhcm	426	8	done	do	VBN
cord-009417-458rrhcm	426	9	more	more	JJR
cord-009417-458rrhcm	426	10	to	to	TO
cord-009417-458rrhcm	426	11	revolutionize	revolutionize	VB
cord-009417-458rrhcm	426	12	transfusion	transfusion	NN
cord-009417-458rrhcm	426	13	practice	practice	NN
cord-009417-458rrhcm	426	14	than	than	IN
cord-009417-458rrhcm	426	15	any	any	DT
cord-009417-458rrhcm	426	16	other	other	JJ
cord-009417-458rrhcm	426	17	transfusion	transfusion	NN
cord-009417-458rrhcm	426	18	risk	risk	NN
cord-009417-458rrhcm	426	19	by	by	IN
cord-009417-458rrhcm	426	20	resulting	result	VBG
cord-009417-458rrhcm	426	21	in	in	IN
cord-009417-458rrhcm	426	22	more	more	JJR
cord-009417-458rrhcm	426	23	conservative	conservative	JJ
cord-009417-458rrhcm	426	24	blood	blood	NN
cord-009417-458rrhcm	426	25	use	use	NN
cord-009417-458rrhcm	426	26	,	,	,
cord-009417-458rrhcm	426	27	more	more	RBR
cord-009417-458rrhcm	426	28	stringent	stringent	JJ
cord-009417-458rrhcm	426	29	donor	donor	NN
cord-009417-458rrhcm	426	30	selection	selection	NN
cord-009417-458rrhcm	426	31	criteria	criterion	NNS
cord-009417-458rrhcm	426	32	,	,	,
cord-009417-458rrhcm	426	33	and	and	CC
cord-009417-458rrhcm	426	34	improved	improved	JJ
cord-009417-458rrhcm	426	35	screening	screening	NN
cord-009417-458rrhcm	426	36	tests	test	NNS
cord-009417-458rrhcm	426	37	.	.	.
cord-009417-458rrhcm	427	1	The	the	DT
cord-009417-458rrhcm	427	2	result	result	NN
cord-009417-458rrhcm	427	3	is	be	VBZ
cord-009417-458rrhcm	427	4	that	that	IN
cord-009417-458rrhcm	427	5	viral	viral	JJ
cord-009417-458rrhcm	427	6	transmission	transmission	NN
cord-009417-458rrhcm	427	7	rates	rate	NNS
cord-009417-458rrhcm	427	8	are	be	VBP
cord-009417-458rrhcm	427	9	now	now	RB
cord-009417-458rrhcm	427	10	diffi	diffi	JJ
cord-009417-458rrhcm	427	11	cult	cult	NN
cord-009417-458rrhcm	427	12	to	to	TO
cord-009417-458rrhcm	427	13	measure	measure	VB
cord-009417-458rrhcm	427	14	,	,	,
cord-009417-458rrhcm	427	15	and	and	CC
cord-009417-458rrhcm	427	16	the	the	DT
cord-009417-458rrhcm	427	17	risk	risk	NN
cord-009417-458rrhcm	427	18	of	of	IN
cord-009417-458rrhcm	427	19	transfusionrelated	transfusionrelated	JJ
cord-009417-458rrhcm	427	20	infectious	infectious	JJ
cord-009417-458rrhcm	427	21	diseases	disease	NNS
cord-009417-458rrhcm	427	22	is	be	VBZ
cord-009417-458rrhcm	427	23	lower	low	JJR
cord-009417-458rrhcm	427	24	than	than	IN
cord-009417-458rrhcm	427	25	ever	ever	RB
cord-009417-458rrhcm	427	26	.	.	.
cord-009417-458rrhcm	428	1	92	92	CD
cord-009417-458rrhcm	429	1	The	the	DT
cord-009417-458rrhcm	429	2	current	current	JJ
cord-009417-458rrhcm	429	3	best	good	JJS
cord-009417-458rrhcm	429	4	estimate	estimate	NN
cord-009417-458rrhcm	429	5	is	be	VBZ
cord-009417-458rrhcm	429	6	that	that	IN
cord-009417-458rrhcm	429	7	3	3	CD
cord-009417-458rrhcm	429	8	to	to	TO
cord-009417-458rrhcm	429	9	4	4	CD
cord-009417-458rrhcm	429	10	units	unit	NNS
cord-009417-458rrhcm	429	11	per	per	IN
cord-009417-458rrhcm	429	12	10,000	10,000	CD
cord-009417-458rrhcm	429	13	will	will	MD
cord-009417-458rrhcm	429	14	transmit	transmit	VB
cord-009417-458rrhcm	429	15	some	some	DT
cord-009417-458rrhcm	429	16	kind	kind	NN
cord-009417-458rrhcm	429	17	of	of	IN
cord-009417-458rrhcm	429	18	infection	infection	NN
cord-009417-458rrhcm	429	19	93	93	CD
cord-009417-458rrhcm	429	20	if	if	IN
cord-009417-458rrhcm	429	21	agents	agent	NNS
cord-009417-458rrhcm	429	22	such	such	JJ
cord-009417-458rrhcm	429	23	as	as	IN
cord-009417-458rrhcm	429	24	CMV	CMV	NNP
cord-009417-458rrhcm	429	25	or	or	CC
cord-009417-458rrhcm	429	26	Epstein	Epstein	NNP
cord-009417-458rrhcm	429	27	-	-	HYPH
cord-009417-458rrhcm	429	28	Barr	Barr	NNP
cord-009417-458rrhcm	429	29	virus	virus	NN
cord-009417-458rrhcm	429	30	are	be	VBP
cord-009417-458rrhcm	429	31	included	include	VBN
cord-009417-458rrhcm	429	32	.	.	.
cord-009417-458rrhcm	430	1	Bacterial	bacterial	JJ
cord-009417-458rrhcm	430	2	infection	infection	NN
cord-009417-458rrhcm	430	3	has	have	VBZ
cord-009417-458rrhcm	430	4	become	become	VBN
cord-009417-458rrhcm	430	5	the	the	DT
cord-009417-458rrhcm	430	6	most	most	RBS
cord-009417-458rrhcm	430	7	common	common	JJ
cord-009417-458rrhcm	430	8	infectious	infectious	JJ
cord-009417-458rrhcm	430	9	risk	risk	NN
cord-009417-458rrhcm	430	10	thanks	thank	NNS
cord-009417-458rrhcm	430	11	to	to	IN
cord-009417-458rrhcm	430	12	increasingly	increasingly	RB
cord-009417-458rrhcm	430	13	sensitive	sensitive	JJ
cord-009417-458rrhcm	430	14	donor	donor	NN
cord-009417-458rrhcm	430	15	screening	screening	NN
cord-009417-458rrhcm	430	16	tests	test	NNS
cord-009417-458rrhcm	430	17	,	,	,
cord-009417-458rrhcm	430	18	including	include	VBG
cord-009417-458rrhcm	430	19	nucleic	nucleic	JJ
cord-009417-458rrhcm	430	20	acid	acid	NN
cord-009417-458rrhcm	430	21	testing	testing	NN
cord-009417-458rrhcm	430	22	(	(	-LRB-
cord-009417-458rrhcm	430	23	NAT	NAT	NNP
cord-009417-458rrhcm	430	24	)	)	-RRB-
cord-009417-458rrhcm	430	25	to	to	TO
cord-009417-458rrhcm	430	26	detect	detect	VB
cord-009417-458rrhcm	430	27	viral	viral	JJ
cord-009417-458rrhcm	430	28	DNA	dna	NN
cord-009417-458rrhcm	430	29	or	or	CC
cord-009417-458rrhcm	430	30	RNA	RNA	NNP
cord-009417-458rrhcm	430	31	,	,	,
cord-009417-458rrhcm	430	32	which	which	WDT
cord-009417-458rrhcm	430	33	has	have	VBZ
cord-009417-458rrhcm	430	34	shortened	shorten	VBN
cord-009417-458rrhcm	430	35	the	the	DT
cord-009417-458rrhcm	430	36	infectious	infectious	JJ
cord-009417-458rrhcm	430	37	period	period	NN
cord-009417-458rrhcm	430	38	and	and	CC
cord-009417-458rrhcm	430	39	reduced	reduce	VBD
cord-009417-458rrhcm	430	40	the	the	DT
cord-009417-458rrhcm	430	41	risk	risk	NN
cord-009417-458rrhcm	430	42	for	for	IN
cord-009417-458rrhcm	430	43	post	post	JJ
cord-009417-458rrhcm	430	44	-	-	JJ
cord-009417-458rrhcm	430	45	transfusion	transfusion	JJ
cord-009417-458rrhcm	430	46	hepatitis	hepatitis	NN
cord-009417-458rrhcm	430	47	(	(	-LRB-
cord-009417-458rrhcm	430	48	PTH	PTH	NNP
cord-009417-458rrhcm	430	49	)	)	-RRB-
cord-009417-458rrhcm	430	50	and	and	CC
cord-009417-458rrhcm	430	51	other	other	JJ
cord-009417-458rrhcm	430	52	viral	viral	JJ
cord-009417-458rrhcm	430	53	infections	infection	NNS
cord-009417-458rrhcm	430	54	.	.	.
cord-009417-458rrhcm	431	1	Several	several	JJ
cord-009417-458rrhcm	431	2	fatalities	fatality	NNS
cord-009417-458rrhcm	431	3	are	be	VBP
cord-009417-458rrhcm	431	4	reported	report	VBN
cord-009417-458rrhcm	431	5	yearly	yearly	RB
cord-009417-458rrhcm	431	6	from	from	IN
cord-009417-458rrhcm	431	7	the	the	DT
cord-009417-458rrhcm	431	8	transfusion	transfusion	NN
cord-009417-458rrhcm	431	9	of	of	IN
cord-009417-458rrhcm	431	10	blood	blood	NN
cord-009417-458rrhcm	431	11	components	component	NNS
cord-009417-458rrhcm	431	12	contaminated	contaminate	VBN
cord-009417-458rrhcm	431	13	with	with	IN
cord-009417-458rrhcm	431	14	viable	viable	JJ
cord-009417-458rrhcm	431	15	,	,	,
cord-009417-458rrhcm	431	16	proliferating	proliferate	VBG
cord-009417-458rrhcm	431	17	bacteria	bacteria	NNS
cord-009417-458rrhcm	431	18	,	,	,
cord-009417-458rrhcm	431	19	with	with	IN
cord-009417-458rrhcm	431	20	or	or	CC
cord-009417-458rrhcm	431	21	without	without	IN
cord-009417-458rrhcm	431	22	the	the	DT
cord-009417-458rrhcm	431	23	accumulation	accumulation	NN
cord-009417-458rrhcm	431	24	of	of	IN
cord-009417-458rrhcm	431	25	endotoxin	endotoxin	NN
cord-009417-458rrhcm	431	26	.	.	.
cord-009417-458rrhcm	432	1	94	94	CD
cord-009417-458rrhcm	432	2	Platelet	platelet	NN
cord-009417-458rrhcm	432	3	concentrates	concentrate	VBZ
cord-009417-458rrhcm	432	4	,	,	,
cord-009417-458rrhcm	432	5	because	because	IN
cord-009417-458rrhcm	432	6	they	-PRON-	PRP
cord-009417-458rrhcm	432	7	must	must	MD
cord-009417-458rrhcm	432	8	be	be	VB
cord-009417-458rrhcm	432	9	stored	store	VBN
cord-009417-458rrhcm	432	10	at	at	IN
cord-009417-458rrhcm	432	11	room	room	NN
cord-009417-458rrhcm	432	12	temperature	temperature	NN
cord-009417-458rrhcm	432	13	,	,	,
cord-009417-458rrhcm	432	14	are	be	VBP
cord-009417-458rrhcm	432	15	particularly	particularly	RB
cord-009417-458rrhcm	432	16	prone	prone	JJ
cord-009417-458rrhcm	432	17	to	to	IN
cord-009417-458rrhcm	432	18	bacterial	bacterial	JJ
cord-009417-458rrhcm	432	19	growth	growth	NN
cord-009417-458rrhcm	432	20	,	,	,
cord-009417-458rrhcm	432	21	with	with	IN
cord-009417-458rrhcm	432	22	a	a	DT
cord-009417-458rrhcm	432	23	reported	report	VBN
cord-009417-458rrhcm	432	24	incidence	incidence	NN
cord-009417-458rrhcm	432	25	of	of	IN
cord-009417-458rrhcm	432	26	6	6	CD
cord-009417-458rrhcm	432	27	in	in	IN
cord-009417-458rrhcm	432	28	10,000	10,000	CD
cord-009417-458rrhcm	432	29	transfusions	transfusion	NNS
cord-009417-458rrhcm	432	30	.	.	.
cord-009417-458rrhcm	433	1	95	95	CD
cord-009417-458rrhcm	433	2	Organisms	organism	NNS
cord-009417-458rrhcm	433	3	isolated	isolate	VBN
cord-009417-458rrhcm	433	4	from	from	IN
cord-009417-458rrhcm	433	5	platelets	platelet	NNS
cord-009417-458rrhcm	433	6	and	and	CC
cord-009417-458rrhcm	433	7	implicated	implicate	VBN
cord-009417-458rrhcm	433	8	in	in	IN
cord-009417-458rrhcm	433	9	fatal	fatal	JJ
cord-009417-458rrhcm	433	10	transfusion	transfusion	NN
cord-009417-458rrhcm	433	11	reactions	reaction	NNS
cord-009417-458rrhcm	433	12	include	include	VBP
cord-009417-458rrhcm	433	13	Staphylococcus	Staphylococcus	NNP
cord-009417-458rrhcm	433	14	and	and	CC
cord-009417-458rrhcm	433	15	Streptococcus	Streptococcus	NNP
cord-009417-458rrhcm	433	16	species	specie	NNS
cord-009417-458rrhcm	433	17	and	and	CC
cord-009417-458rrhcm	433	18	gram	gram	NN
cord-009417-458rrhcm	433	19	-	-	HYPH
cord-009417-458rrhcm	433	20	negative	negative	JJ
cord-009417-458rrhcm	433	21	bacilli	bacilli	NN
cord-009417-458rrhcm	433	22	.	.	.
cord-009417-458rrhcm	434	1	Fatalities	fatality	NNS
cord-009417-458rrhcm	434	2	resulting	result	VBG
cord-009417-458rrhcm	434	3	from	from	IN
cord-009417-458rrhcm	434	4	bacterial	bacterial	JJ
cord-009417-458rrhcm	434	5	contamination	contamination	NN
cord-009417-458rrhcm	434	6	of	of	IN
cord-009417-458rrhcm	434	7	refrigerated	refrigerated	JJ
cord-009417-458rrhcm	434	8	RBCs	rbc	NNS
cord-009417-458rrhcm	434	9	have	have	VBP
cord-009417-458rrhcm	434	10	occurred	occur	VBN
cord-009417-458rrhcm	434	11	as	as	RB
cord-009417-458rrhcm	434	12	well	well	RB
cord-009417-458rrhcm	434	13	and	and	CC
cord-009417-458rrhcm	434	14	more	more	RBR
cord-009417-458rrhcm	434	15	often	often	RB
cord-009417-458rrhcm	434	16	involve	involve	VBP
cord-009417-458rrhcm	434	17	cryophilic	cryophilic	JJ
cord-009417-458rrhcm	434	18	bacteria	bacteria	NNS
cord-009417-458rrhcm	434	19	.	.	.
cord-009417-458rrhcm	435	1	RBC	RBC	NNP
cord-009417-458rrhcm	435	2	transfusions	transfusion	NNS
cord-009417-458rrhcm	435	3	contaminated	contaminate	VBN
cord-009417-458rrhcm	435	4	by	by	IN
cord-009417-458rrhcm	435	5	Yersinia	Yersinia	NNP
cord-009417-458rrhcm	435	6	enterocolitica	enterocolitica	NNP
cord-009417-458rrhcm	435	7	have	have	VBP
cord-009417-458rrhcm	435	8	been	be	VBN
cord-009417-458rrhcm	435	9	consistently	consistently	RB
cord-009417-458rrhcm	435	10	reported	report	VBN
cord-009417-458rrhcm	435	11	for	for	IN
cord-009417-458rrhcm	435	12	a	a	DT
cord-009417-458rrhcm	435	13	decade	decade	NN
cord-009417-458rrhcm	435	14	.	.	.
cord-009417-458rrhcm	436	1	96	96	CD
cord-009417-458rrhcm	436	2	Transfusion	transfusion	NN
cord-009417-458rrhcm	436	3	reactions	reaction	NNS
cord-009417-458rrhcm	436	4	caused	cause	VBN
cord-009417-458rrhcm	436	5	by	by	IN
cord-009417-458rrhcm	436	6	bacterial	bacterial	JJ
cord-009417-458rrhcm	436	7	or	or	CC
cord-009417-458rrhcm	436	8	endotoxin	endotoxin	NN
cord-009417-458rrhcm	436	9	contamination	contamination	NN
cord-009417-458rrhcm	436	10	are	be	VBP
cord-009417-458rrhcm	436	11	fortunately	fortunately	RB
cord-009417-458rrhcm	436	12	quite	quite	RB
cord-009417-458rrhcm	436	13	rare	rare	JJ
cord-009417-458rrhcm	436	14	,	,	,
cord-009417-458rrhcm	436	15	but	but	CC
cord-009417-458rrhcm	436	16	mortality	mortality	NN
cord-009417-458rrhcm	436	17	exceeds	exceed	VBZ
cord-009417-458rrhcm	436	18	60	60	CD
cord-009417-458rrhcm	436	19	%	%	NN
cord-009417-458rrhcm	436	20	.	.	.
cord-009417-458rrhcm	437	1	Signs	sign	NNS
cord-009417-458rrhcm	437	2	and	and	CC
cord-009417-458rrhcm	437	3	symptoms	symptom	NNS
cord-009417-458rrhcm	437	4	of	of	IN
cord-009417-458rrhcm	437	5	reactions	reaction	NNS
cord-009417-458rrhcm	437	6	caused	cause	VBN
cord-009417-458rrhcm	437	7	by	by	IN
cord-009417-458rrhcm	437	8	microbial	microbial	JJ
cord-009417-458rrhcm	437	9	contamination	contamination	NN
cord-009417-458rrhcm	437	10	overlap	overlap	VBP
cord-009417-458rrhcm	437	11	those	those	DT
cord-009417-458rrhcm	437	12	of	of	IN
cord-009417-458rrhcm	437	13	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	437	14	transfusion	transfusion	NN
cord-009417-458rrhcm	437	15	reactions	reaction	NNS
cord-009417-458rrhcm	437	16	and	and	CC
cord-009417-458rrhcm	437	17	consist	consist	VBP
cord-009417-458rrhcm	437	18	primarily	primarily	RB
cord-009417-458rrhcm	437	19	of	of	IN
cord-009417-458rrhcm	437	20	fever	fever	NN
cord-009417-458rrhcm	437	21	and	and	CC
cord-009417-458rrhcm	437	22	hypotension	hypotension	NN
cord-009417-458rrhcm	437	23	,	,	,
cord-009417-458rrhcm	437	24	along	along	IN
cord-009417-458rrhcm	437	25	with	with	IN
cord-009417-458rrhcm	437	26	other	other	JJ
cord-009417-458rrhcm	437	27	signs	sign	NNS
cord-009417-458rrhcm	437	28	of	of	IN
cord-009417-458rrhcm	437	29	endotoxic	endotoxic	JJ
cord-009417-458rrhcm	437	30	shock	shock	NN
cord-009417-458rrhcm	437	31	.	.	.
cord-009417-458rrhcm	438	1	If	if	IN
cord-009417-458rrhcm	438	2	recognized	recognize	VBN
cord-009417-458rrhcm	438	3	promptly	promptly	RB
cord-009417-458rrhcm	438	4	,	,	,
cord-009417-458rrhcm	438	5	a	a	DT
cord-009417-458rrhcm	438	6	Gram	Gram	NNP
cord-009417-458rrhcm	438	7	stain	stain	NN
cord-009417-458rrhcm	438	8	of	of	IN
cord-009417-458rrhcm	438	9	the	the	DT
cord-009417-458rrhcm	438	10	implicated	implicated	JJ
cord-009417-458rrhcm	438	11	unit	unit	NN
cord-009417-458rrhcm	438	12	can	can	MD
cord-009417-458rrhcm	438	13	be	be	VB
cord-009417-458rrhcm	438	14	prepared	prepare	VBN
cord-009417-458rrhcm	438	15	immediately	immediately	RB
cord-009417-458rrhcm	438	16	and	and	CC
cord-009417-458rrhcm	438	17	,	,	,
cord-009417-458rrhcm	438	18	if	if	IN
cord-009417-458rrhcm	438	19	positive	positive	JJ
cord-009417-458rrhcm	438	20	,	,	,
cord-009417-458rrhcm	438	21	appropriate	appropriate	JJ
cord-009417-458rrhcm	438	22	antibiotic	antibiotic	JJ
cord-009417-458rrhcm	438	23	and	and	CC
cord-009417-458rrhcm	438	24	supportive	supportive	JJ
cord-009417-458rrhcm	438	25	therapy	therapy	NN
cord-009417-458rrhcm	438	26	instituted	institute	VBD
cord-009417-458rrhcm	438	27	.	.	.
cord-009417-458rrhcm	439	1	Autologous	autologous	JJ
cord-009417-458rrhcm	439	2	blood	blood	NN
cord-009417-458rrhcm	439	3	components	component	NNS
cord-009417-458rrhcm	439	4	may	may	MD
cord-009417-458rrhcm	439	5	also	also	RB
cord-009417-458rrhcm	439	6	be	be	VB
cord-009417-458rrhcm	439	7	contaminated	contaminate	VBN
cord-009417-458rrhcm	439	8	at	at	IN
cord-009417-458rrhcm	439	9	the	the	DT
cord-009417-458rrhcm	439	10	time	time	NN
cord-009417-458rrhcm	439	11	of	of	IN
cord-009417-458rrhcm	439	12	collection	collection	NN
cord-009417-458rrhcm	439	13	;	;	:
cord-009417-458rrhcm	439	14	therefore	therefore	RB
cord-009417-458rrhcm	439	15	,	,	,
cord-009417-458rrhcm	439	16	reactions	reaction	NNS
cord-009417-458rrhcm	439	17	occurring	occur	VBG
cord-009417-458rrhcm	439	18	in	in	IN
cord-009417-458rrhcm	439	19	patients	patient	NNS
cord-009417-458rrhcm	439	20	who	who	WP
cord-009417-458rrhcm	439	21	are	be	VBP
cord-009417-458rrhcm	439	22	receiving	receive	VBG
cord-009417-458rrhcm	439	23	their	-PRON-	PRP$
cord-009417-458rrhcm	439	24	own	own	JJ
cord-009417-458rrhcm	439	25	blood	blood	NN
cord-009417-458rrhcm	439	26	should	should	MD
cord-009417-458rrhcm	439	27	not	not	RB
cord-009417-458rrhcm	439	28	be	be	VB
cord-009417-458rrhcm	439	29	dismissed	dismiss	VBN
cord-009417-458rrhcm	439	30	but	but	CC
cord-009417-458rrhcm	439	31	instead	instead	RB
cord-009417-458rrhcm	439	32	should	should	MD
cord-009417-458rrhcm	439	33	be	be	VB
cord-009417-458rrhcm	439	34	evaluated	evaluate	VBN
cord-009417-458rrhcm	439	35	as	as	RB
cord-009417-458rrhcm	439	36	fully	fully	RB
cord-009417-458rrhcm	439	37	as	as	IN
cord-009417-458rrhcm	439	38	though	though	IN
cord-009417-458rrhcm	439	39	the	the	DT
cord-009417-458rrhcm	439	40	patients	patient	NNS
cord-009417-458rrhcm	439	41	had	have	VBD
cord-009417-458rrhcm	439	42	received	receive	VBN
cord-009417-458rrhcm	439	43	allogeneic	allogeneic	IN
cord-009417-458rrhcm	439	44	blood	blood	NN
cord-009417-458rrhcm	439	45	.	.	.
cord-009417-458rrhcm	440	1	The	the	DT
cord-009417-458rrhcm	440	2	success	success	NN
cord-009417-458rrhcm	440	3	of	of	IN
cord-009417-458rrhcm	440	4	viral	viral	JJ
cord-009417-458rrhcm	440	5	screening	screening	NN
cord-009417-458rrhcm	440	6	measures	measure	NNS
cord-009417-458rrhcm	440	7	is	be	VBZ
cord-009417-458rrhcm	440	8	most	most	RBS
cord-009417-458rrhcm	440	9	clearly	clearly	RB
cord-009417-458rrhcm	440	10	illustrated	illustrate	VBN
cord-009417-458rrhcm	440	11	by	by	IN
cord-009417-458rrhcm	440	12	the	the	DT
cord-009417-458rrhcm	440	13	fall	fall	NN
cord-009417-458rrhcm	440	14	in	in	IN
cord-009417-458rrhcm	440	15	the	the	DT
cord-009417-458rrhcm	440	16	risk	risk	NN
cord-009417-458rrhcm	440	17	for	for	IN
cord-009417-458rrhcm	440	18	PTH	PTH	NNP
cord-009417-458rrhcm	440	19	over	over	IN
cord-009417-458rrhcm	440	20	the	the	DT
cord-009417-458rrhcm	440	21	past	past	JJ
cord-009417-458rrhcm	440	22	2	2	CD
cord-009417-458rrhcm	440	23	decades	decade	NNS
cord-009417-458rrhcm	440	24	.	.	.
cord-009417-458rrhcm	441	1	Although	although	IN
cord-009417-458rrhcm	441	2	PTH	PTH	NNP
cord-009417-458rrhcm	441	3	continues	continue	VBZ
cord-009417-458rrhcm	441	4	to	to	TO
cord-009417-458rrhcm	441	5	be	be	VB
cord-009417-458rrhcm	441	6	a	a	DT
cord-009417-458rrhcm	441	7	signifi	signifi	NN
cord-009417-458rrhcm	441	8	ca	can	MD
cord-009417-458rrhcm	441	9	nt	not	RB
cord-009417-458rrhcm	441	10	cause	cause	VB
cord-009417-458rrhcm	441	11	of	of	IN
cord-009417-458rrhcm	441	12	morbidity	morbidity	NN
cord-009417-458rrhcm	441	13	and	and	CC
cord-009417-458rrhcm	441	14	mortality	mortality	NN
cord-009417-458rrhcm	441	15	,	,	,
cord-009417-458rrhcm	441	16	the	the	DT
cord-009417-458rrhcm	441	17	nature	nature	NN
cord-009417-458rrhcm	441	18	of	of	IN
cord-009417-458rrhcm	441	19	PTH	PTH	NNP
cord-009417-458rrhcm	441	20	has	have	VBZ
cord-009417-458rrhcm	441	21	changed	change	VBN
cord-009417-458rrhcm	441	22	through	through	IN
cord-009417-458rrhcm	441	23	the	the	DT
cord-009417-458rrhcm	441	24	years	year	NNS
cord-009417-458rrhcm	441	25	with	with	IN
cord-009417-458rrhcm	441	26	the	the	DT
cord-009417-458rrhcm	441	27	stepwise	stepwise	JJ
cord-009417-458rrhcm	441	28	institution	institution	NN
cord-009417-458rrhcm	441	29	of	of	IN
cord-009417-458rrhcm	441	30	various	various	JJ
cord-009417-458rrhcm	441	31	donor	donor	NN
cord-009417-458rrhcm	441	32	screening	screening	NN
cord-009417-458rrhcm	441	33	measures	measure	NNS
cord-009417-458rrhcm	441	34	.	.	.
cord-009417-458rrhcm	442	1	The	the	DT
cord-009417-458rrhcm	442	2	elimination	elimination	NN
cord-009417-458rrhcm	442	3	of	of	IN
cord-009417-458rrhcm	442	4	paid	pay	VBN
cord-009417-458rrhcm	442	5	donors	donor	NNS
cord-009417-458rrhcm	442	6	in	in	IN
cord-009417-458rrhcm	442	7	1972	1972	CD
cord-009417-458rrhcm	442	8	and	and	CC
cord-009417-458rrhcm	442	9	the	the	DT
cord-009417-458rrhcm	442	10	successive	successive	JJ
cord-009417-458rrhcm	442	11	introduction	introduction	NN
cord-009417-458rrhcm	442	12	of	of	IN
cord-009417-458rrhcm	442	13	immunologic	immunologic	JJ
cord-009417-458rrhcm	442	14	tests	test	NNS
cord-009417-458rrhcm	442	15	for	for	IN
cord-009417-458rrhcm	442	16	hepatitis	hepatitis	NN
cord-009417-458rrhcm	442	17	B	B	NNP
cord-009417-458rrhcm	442	18	have	have	VBP
cord-009417-458rrhcm	442	19	resulted	result	VBN
cord-009417-458rrhcm	442	20	in	in	IN
cord-009417-458rrhcm	442	21	a	a	DT
cord-009417-458rrhcm	442	22	steady	steady	JJ
cord-009417-458rrhcm	442	23	reduction	reduction	NN
cord-009417-458rrhcm	442	24	in	in	IN
cord-009417-458rrhcm	442	25	the	the	DT
cord-009417-458rrhcm	442	26	rates	rate	NNS
cord-009417-458rrhcm	442	27	of	of	IN
cord-009417-458rrhcm	442	28	PTH	PTH	NNP
cord-009417-458rrhcm	442	29	caused	cause	VBN
cord-009417-458rrhcm	442	30	by	by	IN
cord-009417-458rrhcm	442	31	hepatitis	hepatitis	NNP
cord-009417-458rrhcm	442	32	B	B	NNP
cord-009417-458rrhcm	442	33	virus	virus	NN
cord-009417-458rrhcm	442	34	(	(	-LRB-
cord-009417-458rrhcm	442	35	HBV	HBV	NNP
cord-009417-458rrhcm	442	36	)	)	-RRB-
cord-009417-458rrhcm	442	37	to	to	IN
cord-009417-458rrhcm	442	38	approximately	approximately	RB
cord-009417-458rrhcm	442	39	17	17	CD
cord-009417-458rrhcm	442	40	per	per	IN
cord-009417-458rrhcm	442	41	million	million	CD
cord-009417-458rrhcm	442	42	units	unit	NNS
cord-009417-458rrhcm	442	43	of	of	IN
cord-009417-458rrhcm	442	44	transfused	transfuse	VBN
cord-009417-458rrhcm	442	45	blood	blood	NN
cord-009417-458rrhcm	442	46	products	product	NNS
cord-009417-458rrhcm	442	47	.	.	.
cord-009417-458rrhcm	443	1	Although	although	IN
cord-009417-458rrhcm	443	2	about	about	RB
cord-009417-458rrhcm	443	3	30	30	CD
cord-009417-458rrhcm	443	4	%	%	NN
cord-009417-458rrhcm	443	5	to	to	TO
cord-009417-458rrhcm	443	6	40	40	CD
cord-009417-458rrhcm	443	7	%	%	NN
cord-009417-458rrhcm	443	8	of	of	IN
cord-009417-458rrhcm	443	9	HBV	HBV	NNP
cord-009417-458rrhcm	443	10	transmissions	transmission	NNS
cord-009417-458rrhcm	443	11	will	will	MD
cord-009417-458rrhcm	443	12	result	result	VB
cord-009417-458rrhcm	443	13	in	in	IN
cord-009417-458rrhcm	443	14	acute	acute	JJ
cord-009417-458rrhcm	443	15	hepatitis	hepatitis	NN
cord-009417-458rrhcm	443	16	,	,	,
cord-009417-458rrhcm	443	17	chronic	chronic	JJ
cord-009417-458rrhcm	443	18	HBV	HBV	NNP
cord-009417-458rrhcm	443	19	infection	infection	NN
cord-009417-458rrhcm	443	20	develops	develop	VBZ
cord-009417-458rrhcm	443	21	in	in	IN
cord-009417-458rrhcm	443	22	less	less	JJR
cord-009417-458rrhcm	443	23	than	than	IN
cord-009417-458rrhcm	443	24	10	10	CD
cord-009417-458rrhcm	443	25	%	%	NN
cord-009417-458rrhcm	443	26	of	of	IN
cord-009417-458rrhcm	443	27	such	such	JJ
cord-009417-458rrhcm	443	28	patients	patient	NNS
cord-009417-458rrhcm	443	29	.	.	.
cord-009417-458rrhcm	444	1	In	in	IN
cord-009417-458rrhcm	444	2	contrast	contrast	NN
cord-009417-458rrhcm	444	3	,	,	,
cord-009417-458rrhcm	444	4	the	the	DT
cord-009417-458rrhcm	444	5	risk	risk	NN
cord-009417-458rrhcm	444	6	for	for	IN
cord-009417-458rrhcm	444	7	chronic	chronic	JJ
cord-009417-458rrhcm	444	8	hepatitis	hepatitis	NN
cord-009417-458rrhcm	444	9	C	c	NN
cord-009417-458rrhcm	444	10	virus	virus	NN
cord-009417-458rrhcm	444	11	(	(	-LRB-
cord-009417-458rrhcm	444	12	HCV	HCV	NNP
cord-009417-458rrhcm	444	13	)	)	-RRB-
cord-009417-458rrhcm	444	14	infection	infection	NN
cord-009417-458rrhcm	444	15	after	after	IN
cord-009417-458rrhcm	444	16	transfusion	transfusion	NN
cord-009417-458rrhcm	444	17	is	be	VBZ
cord-009417-458rrhcm	444	18	higher	high	JJR
cord-009417-458rrhcm	444	19	,	,	,
cord-009417-458rrhcm	444	20	nearly	nearly	RB
cord-009417-458rrhcm	444	21	50	50	CD
cord-009417-458rrhcm	444	22	%	%	NN
cord-009417-458rrhcm	444	23	,	,	,
cord-009417-458rrhcm	444	24	and	and	CC
cord-009417-458rrhcm	444	25	the	the	DT
cord-009417-458rrhcm	444	26	long	long	JJ
cord-009417-458rrhcm	444	27	-	-	HYPH
cord-009417-458rrhcm	444	28	term	term	NN
cord-009417-458rrhcm	444	29	risk	risk	NN
cord-009417-458rrhcm	444	30	for	for	IN
cord-009417-458rrhcm	444	31	cirrhosis	cirrhosis	NN
cord-009417-458rrhcm	444	32	-	-	HYPH
cord-009417-458rrhcm	444	33	or	or	CC
cord-009417-458rrhcm	444	34	hepatocellular	hepatocellular	JJ
cord-009417-458rrhcm	444	35	carcinoma	carcinoma	NN
cord-009417-458rrhcm	444	36	-	-	HYPH
cord-009417-458rrhcm	444	37	related	relate	VBN
cord-009417-458rrhcm	444	38	mortality	mortality	NN
cord-009417-458rrhcm	444	39	is	be	VBZ
cord-009417-458rrhcm	444	40	about	about	RB
cord-009417-458rrhcm	444	41	15	15	CD
cord-009417-458rrhcm	444	42	%	%	NN
cord-009417-458rrhcm	444	43	over	over	IN
cord-009417-458rrhcm	444	44	more	more	JJR
cord-009417-458rrhcm	444	45	than	than	IN
cord-009417-458rrhcm	444	46	20	20	CD
cord-009417-458rrhcm	444	47	years	year	NNS
cord-009417-458rrhcm	444	48	after	after	IN
cord-009417-458rrhcm	444	49	PTH	PTH	NNP
cord-009417-458rrhcm	444	50	secondary	secondary	JJ
cord-009417-458rrhcm	444	51	to	to	IN
cord-009417-458rrhcm	444	52	HCV	HCV	NNP
cord-009417-458rrhcm	444	53	.	.	.
cord-009417-458rrhcm	445	1	97	97	CD
cord-009417-458rrhcm	445	2	,	,	,
cord-009417-458rrhcm	445	3	98	98	CD
cord-009417-458rrhcm	446	1	The	the	DT
cord-009417-458rrhcm	446	2	clinical	clinical	JJ
cord-009417-458rrhcm	446	3	course	course	NN
cord-009417-458rrhcm	446	4	of	of	IN
cord-009417-458rrhcm	446	5	hepatitis	hepatitis	NN
cord-009417-458rrhcm	446	6	A	A	NNP
cord-009417-458rrhcm	446	7	is	be	VBZ
cord-009417-458rrhcm	446	8	generally	generally	RB
cord-009417-458rrhcm	446	9	milder	mild	JJR
cord-009417-458rrhcm	446	10	,	,	,
cord-009417-458rrhcm	446	11	and	and	CC
cord-009417-458rrhcm	446	12	the	the	DT
cord-009417-458rrhcm	446	13	lack	lack	NN
cord-009417-458rrhcm	446	14	of	of	IN
cord-009417-458rrhcm	446	15	a	a	DT
cord-009417-458rrhcm	446	16	chronic	chronic	JJ
cord-009417-458rrhcm	446	17	carrier	carrier	NN
cord-009417-458rrhcm	446	18	state	state	NN
cord-009417-458rrhcm	446	19	means	mean	VBZ
cord-009417-458rrhcm	446	20	that	that	IN
cord-009417-458rrhcm	446	21	with	with	IN
cord-009417-458rrhcm	446	22	donor	donor	NN
cord-009417-458rrhcm	446	23	screening	screening	NN
cord-009417-458rrhcm	446	24	for	for	IN
cord-009417-458rrhcm	446	25	symptoms	symptom	NNS
cord-009417-458rrhcm	446	26	of	of	IN
cord-009417-458rrhcm	446	27	the	the	DT
cord-009417-458rrhcm	446	28	acute	acute	JJ
cord-009417-458rrhcm	446	29	illness	illness	NN
cord-009417-458rrhcm	446	30	,	,	,
cord-009417-458rrhcm	446	31	the	the	DT
cord-009417-458rrhcm	446	32	risk	risk	NN
cord-009417-458rrhcm	446	33	of	of	IN
cord-009417-458rrhcm	446	34	transmission	transmission	NN
cord-009417-458rrhcm	446	35	is	be	VBZ
cord-009417-458rrhcm	446	36	much	much	RB
cord-009417-458rrhcm	446	37	lower	low	JJR
cord-009417-458rrhcm	446	38	,	,	,
cord-009417-458rrhcm	446	39	estimated	estimate	VBN
cord-009417-458rrhcm	446	40	at	at	IN
cord-009417-458rrhcm	446	41	less	less	JJR
cord-009417-458rrhcm	446	42	than	than	IN
cord-009417-458rrhcm	446	43	one	one	CD
cord-009417-458rrhcm	446	44	in	in	IN
cord-009417-458rrhcm	446	45	a	a	DT
cord-009417-458rrhcm	446	46	million	million	CD
cord-009417-458rrhcm	446	47	units	unit	NNS
cord-009417-458rrhcm	446	48	.	.	.
cord-009417-458rrhcm	447	1	99	99	CD
cord-009417-458rrhcm	448	1	The	the	DT
cord-009417-458rrhcm	448	2	prevalence	prevalence	NN
cord-009417-458rrhcm	448	3	of	of	IN
cord-009417-458rrhcm	448	4	hepatitis	hepatitis	NN
cord-009417-458rrhcm	448	5	B	B	NNP
cord-009417-458rrhcm	448	6	surface	surface	NN
cord-009417-458rrhcm	448	7	antigenemia	antigenemia	NN
cord-009417-458rrhcm	448	8	among	among	IN
cord-009417-458rrhcm	448	9	fi	fi	NNP
cord-009417-458rrhcm	448	10	rst	rst	JJ
cord-009417-458rrhcm	448	11	-	-	HYPH
cord-009417-458rrhcm	448	12	time	time	NN
cord-009417-458rrhcm	448	13	blood	blood	NN
cord-009417-458rrhcm	448	14	donors	donor	NNS
cord-009417-458rrhcm	448	15	is	be	VBZ
cord-009417-458rrhcm	448	16	0.7	0.7	CD
cord-009417-458rrhcm	448	17	%	%	NN
cord-009417-458rrhcm	448	18	,	,	,
cord-009417-458rrhcm	448	19	and	and	CC
cord-009417-458rrhcm	448	20	the	the	DT
cord-009417-458rrhcm	448	21	prevalence	prevalence	NN
cord-009417-458rrhcm	448	22	of	of	IN
cord-009417-458rrhcm	448	23	hepatitis	hepatitis	NN
cord-009417-458rrhcm	448	24	C	C	NNP
cord-009417-458rrhcm	448	25	antibodies	antibody	NNS
cord-009417-458rrhcm	448	26	in	in	IN
cord-009417-458rrhcm	448	27	donors	donor	NNS
cord-009417-458rrhcm	448	28	is	be	VBZ
cord-009417-458rrhcm	448	29	approximately	approximately	RB
cord-009417-458rrhcm	448	30	0.1	0.1	CD
cord-009417-458rrhcm	448	31	%	%	NN
cord-009417-458rrhcm	448	32	to	to	TO
cord-009417-458rrhcm	448	33	0.5	0.5	CD
cord-009417-458rrhcm	448	34	%	%	NN
cord-009417-458rrhcm	448	35	.	.	.
cord-009417-458rrhcm	449	1	At	at	IN
cord-009417-458rrhcm	449	2	this	this	DT
cord-009417-458rrhcm	449	3	time	time	NN
cord-009417-458rrhcm	449	4	,	,	,
cord-009417-458rrhcm	449	5	given	give	VBN
cord-009417-458rrhcm	449	6	the	the	DT
cord-009417-458rrhcm	449	7	sensitivity	sensitivity	NN
cord-009417-458rrhcm	449	8	of	of	IN
cord-009417-458rrhcm	449	9	current	current	JJ
cord-009417-458rrhcm	449	10	screening	screening	NN
cord-009417-458rrhcm	449	11	assays	assay	NNS
cord-009417-458rrhcm	449	12	,	,	,
cord-009417-458rrhcm	449	13	including	include	VBG
cord-009417-458rrhcm	449	14	the	the	DT
cord-009417-458rrhcm	449	15	latest	late	JJS
cord-009417-458rrhcm	449	16	generation	generation	NN
cord-009417-458rrhcm	449	17	of	of	IN
cord-009417-458rrhcm	449	18	enzyme	enzyme	NN
cord-009417-458rrhcm	449	19	immunoassays	immunoassays	NNP
cord-009417-458rrhcm	449	20	(	(	-LRB-
cord-009417-458rrhcm	449	21	EIAs	EIAs	NNP
cord-009417-458rrhcm	449	22	)	)	-RRB-
cord-009417-458rrhcm	449	23	and	and	CC
cord-009417-458rrhcm	449	24	NAT	NAT	NNP
cord-009417-458rrhcm	449	25	,	,	,
cord-009417-458rrhcm	449	26	the	the	DT
cord-009417-458rrhcm	449	27	current	current	JJ
cord-009417-458rrhcm	449	28	risk	risk	NN
cord-009417-458rrhcm	449	29	of	of	IN
cord-009417-458rrhcm	449	30	PTH	PTH	NNP
cord-009417-458rrhcm	449	31	resulting	result	VBG
cord-009417-458rrhcm	449	32	from	from	IN
cord-009417-458rrhcm	449	33	HCV	HCV	NNP
cord-009417-458rrhcm	449	34	is	be	VBZ
cord-009417-458rrhcm	449	35	believed	believe	VBN
cord-009417-458rrhcm	449	36	to	to	TO
cord-009417-458rrhcm	449	37	be	be	VB
cord-009417-458rrhcm	449	38	about	about	RB
cord-009417-458rrhcm	449	39	1	1	CD
cord-009417-458rrhcm	449	40	in	in	IN
cord-009417-458rrhcm	449	41	150,000	150,000	CD
cord-009417-458rrhcm	449	42	or	or	CC
cord-009417-458rrhcm	449	43	less	less	JJR
cord-009417-458rrhcm	449	44	.	.	.
cord-009417-458rrhcm	450	1	100	100	CD
cord-009417-458rrhcm	451	1	Although	although	IN
cord-009417-458rrhcm	451	2	HBV	HBV	NNP
cord-009417-458rrhcm	451	3	is	be	VBZ
cord-009417-458rrhcm	451	4	still	still	RB
cord-009417-458rrhcm	451	5	implicated	implicate	VBN
cord-009417-458rrhcm	451	6	in	in	IN
cord-009417-458rrhcm	451	7	PTH	PTH	NNP
cord-009417-458rrhcm	451	8	(	(	-LRB-
cord-009417-458rrhcm	451	9	attributable	attributable	JJ
cord-009417-458rrhcm	451	10	to	to	IN
cord-009417-458rrhcm	451	11	the	the	DT
cord-009417-458rrhcm	451	12	seronegative	seronegative	JJ
cord-009417-458rrhcm	451	13	"	"	``
cord-009417-458rrhcm	451	14	window	window	NN
cord-009417-458rrhcm	451	15	"	"	''
cord-009417-458rrhcm	451	16	period	period	NN
cord-009417-458rrhcm	451	17	in	in	IN
cord-009417-458rrhcm	451	18	newly	newly	RB
cord-009417-458rrhcm	451	19	infected	infect	VBN
cord-009417-458rrhcm	451	20	donors	donor	NNS
cord-009417-458rrhcm	451	21	)	)	-RRB-
cord-009417-458rrhcm	451	22	,	,	,
cord-009417-458rrhcm	451	23	the	the	DT
cord-009417-458rrhcm	451	24	risk	risk	NN
cord-009417-458rrhcm	451	25	of	of	IN
cord-009417-458rrhcm	451	26	transfusion	transfusion	NN
cord-009417-458rrhcm	451	27	-	-	HYPH
cord-009417-458rrhcm	451	28	associated	associate	VBN
cord-009417-458rrhcm	451	29	hepatitis	hepatitis	NN
cord-009417-458rrhcm	451	30	B	B	NNP
cord-009417-458rrhcm	451	31	is	be	VBZ
cord-009417-458rrhcm	451	32	about	about	RB
cord-009417-458rrhcm	451	33	1	1	CD
cord-009417-458rrhcm	451	34	in	in	IN
cord-009417-458rrhcm	451	35	200,000	200,000	CD
cord-009417-458rrhcm	451	36	units	unit	NNS
cord-009417-458rrhcm	451	37	.	.	.
cord-009417-458rrhcm	452	1	100	100	CD
cord-009417-458rrhcm	452	2	Retroviruses	Retroviruses	NNPS
cord-009417-458rrhcm	452	3	,	,	,
cord-009417-458rrhcm	452	4	RNA	RNA	NNP
cord-009417-458rrhcm	452	5	-	-	HYPH
cord-009417-458rrhcm	452	6	based	base	VBN
cord-009417-458rrhcm	452	7	viruses	virus	NNS
cord-009417-458rrhcm	452	8	characterized	characterize	VBN
cord-009417-458rrhcm	452	9	by	by	IN
cord-009417-458rrhcm	452	10	their	-PRON-	PRP$
cord-009417-458rrhcm	452	11	reverse	reverse	JJ
cord-009417-458rrhcm	452	12	transcriptase	transcriptase	NN
cord-009417-458rrhcm	452	13	and	and	CC
cord-009417-458rrhcm	452	14	integration	integration	NN
cord-009417-458rrhcm	452	15	into	into	IN
cord-009417-458rrhcm	452	16	the	the	DT
cord-009417-458rrhcm	452	17	host	host	NN
cord-009417-458rrhcm	452	18	genome	genome	NN
cord-009417-458rrhcm	452	19	,	,	,
cord-009417-458rrhcm	452	20	and	and	CC
cord-009417-458rrhcm	452	21	lentiviruses	lentiviruses	NNP
cord-009417-458rrhcm	452	22	,	,	,
cord-009417-458rrhcm	452	23	a	a	DT
cord-009417-458rrhcm	452	24	subset	subset	NN
cord-009417-458rrhcm	452	25	of	of	IN
cord-009417-458rrhcm	452	26	retroviruses	retrovirus	NNS
cord-009417-458rrhcm	452	27	,	,	,
cord-009417-458rrhcm	452	28	are	be	VBP
cord-009417-458rrhcm	452	29	ubiquitous	ubiquitous	JJ
cord-009417-458rrhcm	452	30	in	in	IN
cord-009417-458rrhcm	452	31	animals	animal	NNS
cord-009417-458rrhcm	452	32	and	and	CC
cord-009417-458rrhcm	452	33	were	be	VBD
cord-009417-458rrhcm	452	34	initially	initially	RB
cord-009417-458rrhcm	452	35	identifi	identifi	VBN
cord-009417-458rrhcm	452	36	ed	ed	NNP
cord-009417-458rrhcm	452	37	in	in	IN
cord-009417-458rrhcm	452	38	humans	human	NNS
cord-009417-458rrhcm	452	39	in	in	IN
cord-009417-458rrhcm	452	40	the	the	DT
cord-009417-458rrhcm	452	41	early	early	JJ
cord-009417-458rrhcm	452	42	1980s	1980s	CD
cord-009417-458rrhcm	452	43	.	.	.
cord-009417-458rrhcm	453	1	Those	those	DT
cord-009417-458rrhcm	453	2	known	know	VBN
cord-009417-458rrhcm	453	3	to	to	TO
cord-009417-458rrhcm	453	4	be	be	VB
cord-009417-458rrhcm	453	5	capable	capable	JJ
cord-009417-458rrhcm	453	6	of	of	IN
cord-009417-458rrhcm	453	7	transmission	transmission	NN
cord-009417-458rrhcm	453	8	by	by	IN
cord-009417-458rrhcm	453	9	transfusion	transfusion	NN
cord-009417-458rrhcm	453	10	are	be	VBP
cord-009417-458rrhcm	453	11	HIV-1	HIV-1	NNP
cord-009417-458rrhcm	453	12	,	,	,
cord-009417-458rrhcm	453	13	HIV-2	HIV-2	NNP
cord-009417-458rrhcm	453	14	,	,	,
cord-009417-458rrhcm	453	15	and	and	CC
cord-009417-458rrhcm	453	16	human	human	JJ
cord-009417-458rrhcm	453	17	T	t	NN
cord-009417-458rrhcm	453	18	-	-	HYPH
cord-009417-458rrhcm	453	19	cell	cell	NN
cord-009417-458rrhcm	453	20	leukemia	leukemia	NN
cord-009417-458rrhcm	453	21	/	/	SYM
cord-009417-458rrhcm	453	22	lymphoma	lymphoma	NN
cord-009417-458rrhcm	453	23	virus	virus	NN
cord-009417-458rrhcm	453	24	(	(	-LRB-
cord-009417-458rrhcm	453	25	HTLV	HTLV	NNP
cord-009417-458rrhcm	453	26	)	)	-RRB-
cord-009417-458rrhcm	454	1	I	-PRON-	PRP
cord-009417-458rrhcm	454	2	and	and	CC
cord-009417-458rrhcm	454	3	II	II	NNP
cord-009417-458rrhcm	454	4	.	.	.
cord-009417-458rrhcm	455	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	455	2	-	-	HYPH
cord-009417-458rrhcm	455	3	associated	associate	VBN
cord-009417-458rrhcm	455	4	AIDS	AIDS	NNP
cord-009417-458rrhcm	455	5	was	be	VBD
cord-009417-458rrhcm	455	6	initially	initially	RB
cord-009417-458rrhcm	455	7	reported	report	VBN
cord-009417-458rrhcm	455	8	in	in	IN
cord-009417-458rrhcm	455	9	late	late	JJ
cord-009417-458rrhcm	455	10	1982	1982	CD
cord-009417-458rrhcm	455	11	.	.	.
cord-009417-458rrhcm	456	1	101	101	CD
cord-009417-458rrhcm	457	1	The	the	DT
cord-009417-458rrhcm	457	2	fi	fi	NNP
cord-009417-458rrhcm	457	3	rst	rst	NN
cord-009417-458rrhcm	457	4	report	report	NN
cord-009417-458rrhcm	457	5	of	of	IN
cord-009417-458rrhcm	457	6	an	an	DT
cord-009417-458rrhcm	457	7	associated	associate	VBN
cord-009417-458rrhcm	457	8	viral	viral	JJ
cord-009417-458rrhcm	457	9	agent	agent	NN
cord-009417-458rrhcm	457	10	did	do	VBD
cord-009417-458rrhcm	457	11	not	not	RB
cord-009417-458rrhcm	457	12	appear	appear	VB
cord-009417-458rrhcm	457	13	until	until	IN
cord-009417-458rrhcm	457	14	late	late	JJ
cord-009417-458rrhcm	457	15	in	in	IN
cord-009417-458rrhcm	457	16	1983	1983	CD
cord-009417-458rrhcm	457	17	,	,	,
cord-009417-458rrhcm	457	18	and	and	CC
cord-009417-458rrhcm	457	19	in	in	IN
cord-009417-458rrhcm	457	20	March	March	NNP
cord-009417-458rrhcm	457	21	1985	1985	CD
cord-009417-458rrhcm	457	22	the	the	DT
cord-009417-458rrhcm	457	23	screening	screening	NN
cord-009417-458rrhcm	457	24	enzyme	enzyme	NN
cord-009417-458rrhcm	457	25	-	-	HYPH
cord-009417-458rrhcm	457	26	linked	link	VBN
cord-009417-458rrhcm	457	27	immunosorbent	immunosorbent	JJ
cord-009417-458rrhcm	457	28	assay	assay	NN
cord-009417-458rrhcm	457	29	(	(	-LRB-
cord-009417-458rrhcm	457	30	ELISA	ELISA	NNP
cord-009417-458rrhcm	457	31	)	)	-RRB-
cord-009417-458rrhcm	457	32	to	to	TO
cord-009417-458rrhcm	457	33	detect	detect	VB
cord-009417-458rrhcm	457	34	antibody	antibody	NN
cord-009417-458rrhcm	457	35	to	to	IN
cord-009417-458rrhcm	457	36	HIV-1	HIV-1	NNP
cord-009417-458rrhcm	457	37	was	be	VBD
cord-009417-458rrhcm	457	38	licensed	license	VBN
cord-009417-458rrhcm	457	39	and	and	CC
cord-009417-458rrhcm	457	40	immediately	immediately	RB
cord-009417-458rrhcm	457	41	incorporated	incorporate	VBN
cord-009417-458rrhcm	457	42	into	into	IN
cord-009417-458rrhcm	457	43	the	the	DT
cord-009417-458rrhcm	457	44	blood	blood	NN
cord-009417-458rrhcm	457	45	-	-	HYPH
cord-009417-458rrhcm	457	46	screening	screening	NN
cord-009417-458rrhcm	457	47	process	process	NN
cord-009417-458rrhcm	457	48	.	.	.
cord-009417-458rrhcm	458	1	Improved	improve	VBN
cord-009417-458rrhcm	458	2	confi	confi	NNP
cord-009417-458rrhcm	458	3	dential	dential	JJ
cord-009417-458rrhcm	458	4	donor	donor	NN
cord-009417-458rrhcm	458	5	screening	screening	NN
cord-009417-458rrhcm	458	6	appeared	appear	VBD
cord-009417-458rrhcm	458	7	to	to	TO
cord-009417-458rrhcm	458	8	decrease	decrease	VB
cord-009417-458rrhcm	458	9	the	the	DT
cord-009417-458rrhcm	458	10	risk	risk	NN
cord-009417-458rrhcm	458	11	of	of	IN
cord-009417-458rrhcm	458	12	infectious	infectious	JJ
cord-009417-458rrhcm	458	13	units	unit	NNS
cord-009417-458rrhcm	458	14	appearing	appear	VBG
cord-009417-458rrhcm	458	15	in	in	IN
cord-009417-458rrhcm	458	16	the	the	DT
cord-009417-458rrhcm	458	17	donor	donor	NN
cord-009417-458rrhcm	458	18	pool	pool	NN
cord-009417-458rrhcm	458	19	.	.	.
cord-009417-458rrhcm	459	1	102	102	CD
cord-009417-458rrhcm	459	2	,	,	,
cord-009417-458rrhcm	459	3	103	103	CD
cord-009417-458rrhcm	460	1	The	the	DT
cord-009417-458rrhcm	460	2	discovery	discovery	NN
cord-009417-458rrhcm	460	3	that	that	WDT
cord-009417-458rrhcm	460	4	heat	heat	NN
cord-009417-458rrhcm	460	5	treatment	treatment	NN
cord-009417-458rrhcm	460	6	reduced	reduce	VBN
cord-009417-458rrhcm	460	7	transmission	transmission	NN
cord-009417-458rrhcm	460	8	resulted	result	VBD
cord-009417-458rrhcm	460	9	in	in	IN
cord-009417-458rrhcm	460	10	a	a	DT
cord-009417-458rrhcm	460	11	reduction	reduction	NN
cord-009417-458rrhcm	460	12	in	in	IN
cord-009417-458rrhcm	460	13	transmission	transmission	NN
cord-009417-458rrhcm	460	14	by	by	IN
cord-009417-458rrhcm	460	15	plasma	plasma	NN
cord-009417-458rrhcm	460	16	products	product	NNS
cord-009417-458rrhcm	460	17	,	,	,
cord-009417-458rrhcm	460	18	especially	especially	RB
cord-009417-458rrhcm	460	19	to	to	IN
cord-009417-458rrhcm	460	20	persons	person	NNS
cord-009417-458rrhcm	460	21	with	with	IN
cord-009417-458rrhcm	460	22	hemophilia	hemophilia	NN
cord-009417-458rrhcm	460	23	.	.	.
cord-009417-458rrhcm	461	1	Clinical	clinical	JJ
cord-009417-458rrhcm	461	2	AIDS	AIDS	NNP
cord-009417-458rrhcm	461	3	developed	develop	VBD
cord-009417-458rrhcm	461	4	in	in	IN
cord-009417-458rrhcm	461	5	more	more	JJR
cord-009417-458rrhcm	461	6	than	than	IN
cord-009417-458rrhcm	461	7	90	90	CD
cord-009417-458rrhcm	461	8	%	%	NN
cord-009417-458rrhcm	461	9	of	of	IN
cord-009417-458rrhcm	461	10	recipients	recipient	NNS
cord-009417-458rrhcm	461	11	of	of	IN
cord-009417-458rrhcm	461	12	infected	infected	JJ
cord-009417-458rrhcm	461	13	blood	blood	NN
cord-009417-458rrhcm	461	14	products	product	NNS
cord-009417-458rrhcm	461	15	,	,	,
cord-009417-458rrhcm	461	16	and	and	CC
cord-009417-458rrhcm	461	17	the	the	DT
cord-009417-458rrhcm	461	18	vast	vast	JJ
cord-009417-458rrhcm	461	19	majority	majority	NN
cord-009417-458rrhcm	461	20	succumbed	succumb	VBD
cord-009417-458rrhcm	461	21	to	to	IN
cord-009417-458rrhcm	461	22	the	the	DT
cord-009417-458rrhcm	461	23	disease	disease	NN
cord-009417-458rrhcm	461	24	.	.	.
cord-009417-458rrhcm	462	1	Removal	removal	NN
cord-009417-458rrhcm	462	2	of	of	IN
cord-009417-458rrhcm	462	3	donor	donor	NN
cord-009417-458rrhcm	462	4	units	unit	NNS
cord-009417-458rrhcm	462	5	with	with	IN
cord-009417-458rrhcm	462	6	seropositivity	seropositivity	NN
cord-009417-458rrhcm	462	7	by	by	IN
cord-009417-458rrhcm	462	8	ELISA	ELISA	NNP
cord-009417-458rrhcm	462	9	was	be	VBD
cord-009417-458rrhcm	462	10	insuffi	insuffi	NNP
cord-009417-458rrhcm	462	11	cient	cient	NNP
cord-009417-458rrhcm	462	12	to	to	TO
cord-009417-458rrhcm	462	13	prevent	prevent	VB
cord-009417-458rrhcm	462	14	transmission	transmission	NN
cord-009417-458rrhcm	462	15	of	of	IN
cord-009417-458rrhcm	462	16	HIV-1	HIV-1	NNP
cord-009417-458rrhcm	462	17	;	;	:
cord-009417-458rrhcm	462	18	several	several	JJ
cord-009417-458rrhcm	462	19	hundred	hundred	CD
cord-009417-458rrhcm	462	20	cases	case	NNS
cord-009417-458rrhcm	462	21	were	be	VBD
cord-009417-458rrhcm	462	22	reported	report	VBN
cord-009417-458rrhcm	462	23	annually	annually	RB
cord-009417-458rrhcm	462	24	after	after	IN
cord-009417-458rrhcm	462	25	introduction	introduction	NN
cord-009417-458rrhcm	462	26	of	of	IN
cord-009417-458rrhcm	462	27	the	the	DT
cord-009417-458rrhcm	462	28	ELISA	ELISA	NNP
cord-009417-458rrhcm	462	29	test	test	NN
cord-009417-458rrhcm	462	30	.	.	.
cord-009417-458rrhcm	463	1	Subsequent	subsequent	JJ
cord-009417-458rrhcm	463	2	development	development	NN
cord-009417-458rrhcm	463	3	of	of	IN
cord-009417-458rrhcm	463	4	an	an	DT
cord-009417-458rrhcm	463	5	assay	assay	NN
cord-009417-458rrhcm	463	6	for	for	IN
cord-009417-458rrhcm	463	7	the	the	DT
cord-009417-458rrhcm	463	8	p24	p24	NN
cord-009417-458rrhcm	463	9	antigen	antigen	NN
cord-009417-458rrhcm	463	10	and	and	CC
cord-009417-458rrhcm	463	11	then	then	RB
cord-009417-458rrhcm	463	12	NAT	NAT	NNP
cord-009417-458rrhcm	463	13	has	have	VBZ
cord-009417-458rrhcm	463	14	lowered	lower	VBN
cord-009417-458rrhcm	463	15	the	the	DT
cord-009417-458rrhcm	463	16	risk	risk	NN
cord-009417-458rrhcm	463	17	of	of	IN
cord-009417-458rrhcm	463	18	transfusion	transfusion	NN
cord-009417-458rrhcm	463	19	-	-	HYPH
cord-009417-458rrhcm	463	20	associated	associate	VBN
cord-009417-458rrhcm	463	21	HIV-1	HIV-1	NNP
cord-009417-458rrhcm	463	22	infection	infection	NN
cord-009417-458rrhcm	463	23	to	to	IN
cord-009417-458rrhcm	463	24	less	less	JJR
cord-009417-458rrhcm	463	25	than	than	IN
cord-009417-458rrhcm	463	26	one	one	CD
cord-009417-458rrhcm	463	27	in	in	IN
cord-009417-458rrhcm	463	28	a	a	DT
cord-009417-458rrhcm	463	29	million	million	CD
cord-009417-458rrhcm	463	30	(	(	-LRB-
cord-009417-458rrhcm	463	31	see	see	VB
cord-009417-458rrhcm	463	32	Table	table	NN
cord-009417-458rrhcm	463	33	80	80	CD
cord-009417-458rrhcm	463	34	-3	-3	NNP
cord-009417-458rrhcm	463	35	)	)	-RRB-
cord-009417-458rrhcm	463	36	.	.	.
cord-009417-458rrhcm	464	1	Despite	despite	IN
cord-009417-458rrhcm	464	2	donor	donor	NN
cord-009417-458rrhcm	464	3	screening	screening	NN
cord-009417-458rrhcm	464	4	and	and	CC
cord-009417-458rrhcm	464	5	sensitive	sensitive	JJ
cord-009417-458rrhcm	464	6	assays	assay	NNS
cord-009417-458rrhcm	464	7	,	,	,
cord-009417-458rrhcm	464	8	including	include	VBG
cord-009417-458rrhcm	464	9	EIA	EIA	NNP
cord-009417-458rrhcm	464	10	,	,	,
cord-009417-458rrhcm	464	11	NAT	NAT	NNP
cord-009417-458rrhcm	464	12	,	,	,
cord-009417-458rrhcm	464	13	and	and	CC
cord-009417-458rrhcm	464	14	p24	p24	NN
cord-009417-458rrhcm	464	15	antigen	antigen	NN
cord-009417-458rrhcm	464	16	,	,	,
cord-009417-458rrhcm	464	17	an	an	DT
cord-009417-458rrhcm	464	18	extremely	extremely	RB
cord-009417-458rrhcm	464	19	small	small	JJ
cord-009417-458rrhcm	464	20	,	,	,
cord-009417-458rrhcm	464	21	but	but	CC
cord-009417-458rrhcm	464	22	fi	fi	NN
cord-009417-458rrhcm	464	23	nite	nite	NN
cord-009417-458rrhcm	464	24	risk	risk	NN
cord-009417-458rrhcm	464	25	of	of	IN
cord-009417-458rrhcm	464	26	HIV-1	HIV-1	NNP
cord-009417-458rrhcm	464	27	transmission	transmission	NN
cord-009417-458rrhcm	464	28	by	by	IN
cord-009417-458rrhcm	464	29	screened	screen	VBN
cord-009417-458rrhcm	464	30	blood	blood	NN
cord-009417-458rrhcm	464	31	transfusions	transfusion	NNS
cord-009417-458rrhcm	464	32	remains	remain	VBZ
cord-009417-458rrhcm	464	33	.	.	.
cord-009417-458rrhcm	465	1	This	this	DT
cord-009417-458rrhcm	465	2	risk	risk	NN
cord-009417-458rrhcm	465	3	is	be	VBZ
cord-009417-458rrhcm	465	4	largely	largely	RB
cord-009417-458rrhcm	465	5	due	due	JJ
cord-009417-458rrhcm	465	6	to	to	IN
cord-009417-458rrhcm	465	7	the	the	DT
cord-009417-458rrhcm	465	8	seronegative	seronegative	JJ
cord-009417-458rrhcm	465	9	"	"	``
cord-009417-458rrhcm	465	10	window	window	NN
cord-009417-458rrhcm	465	11	"	"	''
cord-009417-458rrhcm	465	12	period	period	NN
cord-009417-458rrhcm	465	13	experienced	experience	VBN
cord-009417-458rrhcm	465	14	by	by	IN
cord-009417-458rrhcm	465	15	newly	newly	RB
cord-009417-458rrhcm	465	16	infected	infect	VBN
cord-009417-458rrhcm	465	17	donors	donor	NNS
cord-009417-458rrhcm	465	18	,	,	,
cord-009417-458rrhcm	465	19	which	which	WDT
cord-009417-458rrhcm	465	20	is	be	VBZ
cord-009417-458rrhcm	465	21	estimated	estimate	VBN
cord-009417-458rrhcm	465	22	to	to	TO
cord-009417-458rrhcm	465	23	be	be	VB
cord-009417-458rrhcm	465	24	an	an	DT
cord-009417-458rrhcm	465	25	average	average	NN
cord-009417-458rrhcm	465	26	of	of	IN
cord-009417-458rrhcm	465	27	16	16	CD
cord-009417-458rrhcm	465	28	days	day	NNS
cord-009417-458rrhcm	465	29	.	.	.
cord-009417-458rrhcm	466	1	100	100	CD
cord-009417-458rrhcm	467	1	A	a	DT
cord-009417-458rrhcm	467	2	second	second	JJ
cord-009417-458rrhcm	467	3	retrovirus	retrovirus	NN
cord-009417-458rrhcm	467	4	,	,	,
cord-009417-458rrhcm	467	5	HIV-2	HIV-2	NNP
cord-009417-458rrhcm	467	6	,	,	,
cord-009417-458rrhcm	468	1	fi	fi	NNP
cord-009417-458rrhcm	468	2	rst	rst	NNP
cord-009417-458rrhcm	468	3	described	describe	VBN
cord-009417-458rrhcm	468	4	in	in	IN
cord-009417-458rrhcm	468	5	residents	resident	NNS
cord-009417-458rrhcm	468	6	of	of	IN
cord-009417-458rrhcm	468	7	countries	country	NNS
cord-009417-458rrhcm	468	8	in	in	IN
cord-009417-458rrhcm	468	9	West	West	NNP
cord-009417-458rrhcm	468	10	Africa	Africa	NNP
cord-009417-458rrhcm	468	11	and	and	CC
cord-009417-458rrhcm	468	12	subsequently	subsequently	RB
cord-009417-458rrhcm	468	13	detected	detect	VBD
cord-009417-458rrhcm	468	14	in	in	IN
cord-009417-458rrhcm	468	15	migrants	migrant	NNS
cord-009417-458rrhcm	468	16	to	to	IN
cord-009417-458rrhcm	468	17	western	western	JJ
cord-009417-458rrhcm	468	18	Europe	Europe	NNP
cord-009417-458rrhcm	468	19	,	,	,
cord-009417-458rrhcm	468	20	causes	cause	VBZ
cord-009417-458rrhcm	468	21	an	an	DT
cord-009417-458rrhcm	468	22	immunodeficiency	immunodeficiency	NN
cord-009417-458rrhcm	468	23	syndrome	syndrome	NN
cord-009417-458rrhcm	468	24	similar	similar	JJ
cord-009417-458rrhcm	468	25	to	to	IN
cord-009417-458rrhcm	468	26	that	that	DT
cord-009417-458rrhcm	468	27	caused	cause	VBN
cord-009417-458rrhcm	468	28	by	by	IN
cord-009417-458rrhcm	468	29	HIV-1	HIV-1	NNP
cord-009417-458rrhcm	468	30	.	.	.
cord-009417-458rrhcm	469	1	Although	although	IN
cord-009417-458rrhcm	469	2	very	very	RB
cord-009417-458rrhcm	469	3	few	few	JJ
cord-009417-458rrhcm	469	4	cases	case	NNS
cord-009417-458rrhcm	469	5	of	of	IN
cord-009417-458rrhcm	469	6	HIV-2	HIV-2	NNP
cord-009417-458rrhcm	469	7	have	have	VBP
cord-009417-458rrhcm	469	8	been	be	VBN
cord-009417-458rrhcm	469	9	reported	report	VBN
cord-009417-458rrhcm	469	10	in	in	IN
cord-009417-458rrhcm	469	11	the	the	DT
cord-009417-458rrhcm	469	12	United	United	NNP
cord-009417-458rrhcm	469	13	States	States	NNP
cord-009417-458rrhcm	469	14	104	104	CD
cord-009417-458rrhcm	469	15	,	,	,
cord-009417-458rrhcm	469	16	105	105	CD
cord-009417-458rrhcm	469	17	and	and	CC
cord-009417-458rrhcm	469	18	there	there	EX
cord-009417-458rrhcm	469	19	have	have	VBP
cord-009417-458rrhcm	469	20	been	be	VBN
cord-009417-458rrhcm	469	21	no	no	DT
cord-009417-458rrhcm	469	22	reported	report	VBN
cord-009417-458rrhcm	469	23	transfusion	transfusion	NN
cord-009417-458rrhcm	469	24	-	-	HYPH
cord-009417-458rrhcm	469	25	transmitted	transmit	VBN
cord-009417-458rrhcm	469	26	cases	case	NNS
cord-009417-458rrhcm	469	27	,	,	,
cord-009417-458rrhcm	469	28	experience	experience	NN
cord-009417-458rrhcm	469	29	with	with	IN
cord-009417-458rrhcm	469	30	other	other	JJ
cord-009417-458rrhcm	469	31	retroviruses	retrovirus	NNS
cord-009417-458rrhcm	469	32	suggests	suggest	VBZ
cord-009417-458rrhcm	469	33	that	that	IN
cord-009417-458rrhcm	469	34	screening	screening	NN
cord-009417-458rrhcm	469	35	may	may	MD
cord-009417-458rrhcm	469	36	prevent	prevent	VB
cord-009417-458rrhcm	469	37	the	the	DT
cord-009417-458rrhcm	469	38	majority	majority	NN
cord-009417-458rrhcm	469	39	of	of	IN
cord-009417-458rrhcm	469	40	potential	potential	JJ
cord-009417-458rrhcm	469	41	transmission	transmission	NN
cord-009417-458rrhcm	469	42	.	.	.
cord-009417-458rrhcm	470	1	Therefore	therefore	RB
cord-009417-458rrhcm	470	2	,	,	,
cord-009417-458rrhcm	470	3	donated	donate	VBN
cord-009417-458rrhcm	470	4	blood	blood	NN
cord-009417-458rrhcm	470	5	is	be	VBZ
cord-009417-458rrhcm	470	6	now	now	RB
cord-009417-458rrhcm	470	7	screened	screen	VBN
cord-009417-458rrhcm	470	8	by	by	IN
cord-009417-458rrhcm	470	9	an	an	DT
cord-009417-458rrhcm	470	10	assay	assay	NN
cord-009417-458rrhcm	470	11	for	for	IN
cord-009417-458rrhcm	470	12	the	the	DT
cord-009417-458rrhcm	470	13	presence	presence	NN
cord-009417-458rrhcm	470	14	of	of	IN
cord-009417-458rrhcm	470	15	antibody	antibody	NN
cord-009417-458rrhcm	470	16	to	to	IN
cord-009417-458rrhcm	470	17	HIV-2	HIV-2	NNP
cord-009417-458rrhcm	470	18	.	.	.
cord-009417-458rrhcm	471	1	The	the	DT
cord-009417-458rrhcm	471	2	retrovirus	retrovirus	NN
cord-009417-458rrhcm	471	3	HTLV	HTLV	NNP
cord-009417-458rrhcm	471	4	-	-	:
cord-009417-458rrhcm	471	5	I	-PRON-	PRP
cord-009417-458rrhcm	471	6	is	be	VBZ
cord-009417-458rrhcm	471	7	the	the	DT
cord-009417-458rrhcm	471	8	causative	causative	JJ
cord-009417-458rrhcm	471	9	agent	agent	NN
cord-009417-458rrhcm	471	10	of	of	IN
cord-009417-458rrhcm	471	11	adult	adult	NN
cord-009417-458rrhcm	471	12	T	t	NN
cord-009417-458rrhcm	471	13	-	-	HYPH
cord-009417-458rrhcm	471	14	cell	cell	NN
cord-009417-458rrhcm	471	15	leukemia	leukemia	NN
cord-009417-458rrhcm	471	16	(	(	-LRB-
cord-009417-458rrhcm	471	17	ATL	ATL	NNP
cord-009417-458rrhcm	471	18	)	)	-RRB-
cord-009417-458rrhcm	471	19	and	and	CC
cord-009417-458rrhcm	471	20	is	be	VBZ
cord-009417-458rrhcm	471	21	strongly	strongly	RB
cord-009417-458rrhcm	471	22	implicated	implicate	VBN
cord-009417-458rrhcm	471	23	in	in	IN
cord-009417-458rrhcm	471	24	the	the	DT
cord-009417-458rrhcm	471	25	chronic	chronic	JJ
cord-009417-458rrhcm	471	26	,	,	,
cord-009417-458rrhcm	471	27	progressive	progressive	JJ
cord-009417-458rrhcm	471	28	neurologic	neurologic	JJ
cord-009417-458rrhcm	471	29	disorder	disorder	NN
cord-009417-458rrhcm	471	30	termed	term	VBD
cord-009417-458rrhcm	471	31	tropical	tropical	JJ
cord-009417-458rrhcm	471	32	spastic	spastic	JJ
cord-009417-458rrhcm	471	33	paraparesis	paraparesis	NN
cord-009417-458rrhcm	471	34	or	or	CC
cord-009417-458rrhcm	471	35	HTLV	HTLV	NNP
cord-009417-458rrhcm	471	36	-	-	HYPH
cord-009417-458rrhcm	471	37	I	i	NN
cord-009417-458rrhcm	471	38	-	-	HYPH
cord-009417-458rrhcm	471	39	associated	associate	VBN
cord-009417-458rrhcm	471	40	myelopathy	myelopathy	NN
cord-009417-458rrhcm	471	41	(	(	-LRB-
cord-009417-458rrhcm	471	42	TSP	TSP	NNP
cord-009417-458rrhcm	471	43	/	/	SYM
cord-009417-458rrhcm	471	44	HAM	HAM	NNP
cord-009417-458rrhcm	471	45	)	)	-RRB-
cord-009417-458rrhcm	471	46	.	.	.
cord-009417-458rrhcm	472	1	HTLV	HTLV	NNP
cord-009417-458rrhcm	472	2	-	-	HYPH
cord-009417-458rrhcm	472	3	II	II	NNP
cord-009417-458rrhcm	472	4	has	have	VBZ
cord-009417-458rrhcm	472	5	been	be	VBN
cord-009417-458rrhcm	472	6	linked	link	VBN
cord-009417-458rrhcm	472	7	to	to	IN
cord-009417-458rrhcm	472	8	hairy	hairy	JJ
cord-009417-458rrhcm	472	9	cell	cell	NN
cord-009417-458rrhcm	472	10	leukemia	leukemia	NN
cord-009417-458rrhcm	472	11	,	,	,
cord-009417-458rrhcm	472	12	but	but	CC
cord-009417-458rrhcm	472	13	no	no	DT
cord-009417-458rrhcm	472	14	transfusion	transfusion	NN
cord-009417-458rrhcm	472	15	-	-	HYPH
cord-009417-458rrhcm	472	16	transmitted	transmit	VBN
cord-009417-458rrhcm	472	17	cases	case	NNS
cord-009417-458rrhcm	472	18	have	have	VBP
cord-009417-458rrhcm	472	19	been	be	VBN
cord-009417-458rrhcm	472	20	reported	report	VBN
cord-009417-458rrhcm	472	21	.	.	.
cord-009417-458rrhcm	473	1	The	the	DT
cord-009417-458rrhcm	473	2	virus	virus	NN
cord-009417-458rrhcm	473	3	exhibits	exhibit	VBZ
cord-009417-458rrhcm	473	4	strong	strong	JJ
cord-009417-458rrhcm	473	5	serologic	serologic	JJ
cord-009417-458rrhcm	473	6	crossreactivity	crossreactivity	NN
cord-009417-458rrhcm	473	7	with	with	IN
cord-009417-458rrhcm	473	8	HTLV	HTLV	NNP
cord-009417-458rrhcm	473	9	-	-	:
cord-009417-458rrhcm	473	10	I	-PRON-	PRP
cord-009417-458rrhcm	473	11	such	such	JJ
cord-009417-458rrhcm	473	12	that	that	IN
cord-009417-458rrhcm	473	13	screening	screening	NN
cord-009417-458rrhcm	473	14	assays	assay	NNS
cord-009417-458rrhcm	473	15	fail	fail	VBP
cord-009417-458rrhcm	473	16	to	to	TO
cord-009417-458rrhcm	473	17	distinguish	distinguish	VB
cord-009417-458rrhcm	473	18	between	between	IN
cord-009417-458rrhcm	473	19	antibodies	antibody	NNS
cord-009417-458rrhcm	473	20	to	to	IN
cord-009417-458rrhcm	473	21	either	either	DT
cord-009417-458rrhcm	473	22	virus	virus	NN
cord-009417-458rrhcm	473	23	.	.	.
cord-009417-458rrhcm	474	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	474	2	-	-	HYPH
cord-009417-458rrhcm	474	3	transmitted	transmit	VBN
cord-009417-458rrhcm	474	4	HTLV	HTLV	NNP
cord-009417-458rrhcm	475	1	-I	-I	NNP
cord-009417-458rrhcm	475	2	has	have	VBZ
cord-009417-458rrhcm	475	3	been	be	VBN
cord-009417-458rrhcm	475	4	demonstrated	demonstrate	VBN
cord-009417-458rrhcm	475	5	.	.	.
cord-009417-458rrhcm	476	1	106	106	CD
cord-009417-458rrhcm	476	2	TSP	TSP	NNP
cord-009417-458rrhcm	476	3	/	/	SYM
cord-009417-458rrhcm	476	4	HAM	HAM	NNP
cord-009417-458rrhcm	476	5	has	have	VBZ
cord-009417-458rrhcm	476	6	developed	develop	VBN
cord-009417-458rrhcm	476	7	in	in	IN
cord-009417-458rrhcm	476	8	a	a	DT
cord-009417-458rrhcm	476	9	small	small	JJ
cord-009417-458rrhcm	476	10	percentage	percentage	NN
cord-009417-458rrhcm	476	11	of	of	IN
cord-009417-458rrhcm	476	12	infected	infected	JJ
cord-009417-458rrhcm	476	13	transfusion	transfusion	NN
cord-009417-458rrhcm	476	14	recipients	recipient	NNS
cord-009417-458rrhcm	476	15	,	,	,
cord-009417-458rrhcm	476	16	but	but	CC
cord-009417-458rrhcm	476	17	no	no	DT
cord-009417-458rrhcm	476	18	transfusionassociated	transfusionassociate	VBN
cord-009417-458rrhcm	476	19	cases	case	NNS
cord-009417-458rrhcm	476	20	of	of	IN
cord-009417-458rrhcm	476	21	ATL	ATL	NNP
cord-009417-458rrhcm	476	22	have	have	VBP
cord-009417-458rrhcm	476	23	been	be	VBN
cord-009417-458rrhcm	476	24	seen	see	VBN
cord-009417-458rrhcm	476	25	.	.	.
cord-009417-458rrhcm	477	1	Approximately	approximately	RB
cord-009417-458rrhcm	477	2	0.025	0.025	CD
cord-009417-458rrhcm	477	3	%	%	NN
cord-009417-458rrhcm	477	4	of	of	IN
cord-009417-458rrhcm	477	5	donors	donor	NNS
cord-009417-458rrhcm	477	6	in	in	IN
cord-009417-458rrhcm	477	7	the	the	DT
cord-009417-458rrhcm	477	8	United	United	NNP
cord-009417-458rrhcm	477	9	States	States	NNP
cord-009417-458rrhcm	477	10	are	be	VBP
cord-009417-458rrhcm	477	11	seropositive	seropositive	JJ
cord-009417-458rrhcm	477	12	for	for	IN
cord-009417-458rrhcm	477	13	HTLV	HTLV	NNP
cord-009417-458rrhcm	477	14	-	-	HYPH
cord-009417-458rrhcm	477	15	I	I	NNP
cord-009417-458rrhcm	477	16	and	and	CC
cord-009417-458rrhcm	477	17	HTLV	HTLV	NNP
cord-009417-458rrhcm	477	18	-	-	HYPH
cord-009417-458rrhcm	477	19	II	II	NNP
cord-009417-458rrhcm	477	20	107	107	CD
cord-009417-458rrhcm	477	21	;	;	:
cord-009417-458rrhcm	477	22	further	further	RB
cord-009417-458rrhcm	477	23	testing	testing	NN
cord-009417-458rrhcm	477	24	reveals	reveal	VBZ
cord-009417-458rrhcm	477	25	the	the	DT
cord-009417-458rrhcm	477	26	majority	majority	NN
cord-009417-458rrhcm	477	27	of	of	IN
cord-009417-458rrhcm	477	28	them	-PRON-	PRP
cord-009417-458rrhcm	477	29	to	to	TO
cord-009417-458rrhcm	477	30	be	be	VB
cord-009417-458rrhcm	477	31	HTLV	HTLV	NNP
cord-009417-458rrhcm	477	32	-	-	HYPH
cord-009417-458rrhcm	477	33	II	II	NNP
cord-009417-458rrhcm	477	34	.	.	.
cord-009417-458rrhcm	478	1	Donated	donate	VBN
cord-009417-458rrhcm	478	2	blood	blood	NN
cord-009417-458rrhcm	478	3	is	be	VBZ
cord-009417-458rrhcm	478	4	currently	currently	RB
cord-009417-458rrhcm	478	5	screened	screen	VBN
cord-009417-458rrhcm	478	6	for	for	IN
cord-009417-458rrhcm	478	7	antibodies	antibody	NNS
cord-009417-458rrhcm	478	8	to	to	IN
cord-009417-458rrhcm	478	9	HTLV	HTLV	NNP
cord-009417-458rrhcm	478	10	-	-	HYPH
cord-009417-458rrhcm	478	11	I	I	NNP
cord-009417-458rrhcm	478	12	and	and	CC
cord-009417-458rrhcm	478	13	HTLV	HTLV	NNP
cord-009417-458rrhcm	478	14	-	-	HYPH
cord-009417-458rrhcm	478	15	II	II	NNP
cord-009417-458rrhcm	478	16	.	.	.
cord-009417-458rrhcm	479	1	The	the	DT
cord-009417-458rrhcm	479	2	estimated	estimate	VBN
cord-009417-458rrhcm	479	3	risk	risk	NN
cord-009417-458rrhcm	479	4	of	of	IN
cord-009417-458rrhcm	479	5	HTLV	HTLV	NNP
cord-009417-458rrhcm	479	6	transmission	transmission	NN
cord-009417-458rrhcm	479	7	by	by	IN
cord-009417-458rrhcm	479	8	screened	screen	VBN
cord-009417-458rrhcm	479	9	negative	negative	JJ
cord-009417-458rrhcm	479	10	blood	blood	NN
cord-009417-458rrhcm	479	11	is	be	VBZ
cord-009417-458rrhcm	479	12	believed	believe	VBN
cord-009417-458rrhcm	479	13	to	to	TO
cord-009417-458rrhcm	479	14	be	be	VB
cord-009417-458rrhcm	479	15	1	1	CD
cord-009417-458rrhcm	479	16	in	in	IN
cord-009417-458rrhcm	479	17	250,000	250,000	CD
cord-009417-458rrhcm	479	18	to	to	TO
cord-009417-458rrhcm	479	19	2	2	CD
cord-009417-458rrhcm	479	20	million	million	CD
cord-009417-458rrhcm	479	21	.	.	.
cord-009417-458rrhcm	480	1	CMV	CMV	NNP
cord-009417-458rrhcm	480	2	is	be	VBZ
cord-009417-458rrhcm	480	3	a	a	DT
cord-009417-458rrhcm	480	4	human	human	JJ
cord-009417-458rrhcm	480	5	herpesvirus	herpesvirus	NN
cord-009417-458rrhcm	480	6	that	that	WDT
cord-009417-458rrhcm	480	7	establishes	establish	VBZ
cord-009417-458rrhcm	480	8	latent	latent	JJ
cord-009417-458rrhcm	480	9	infection	infection	NN
cord-009417-458rrhcm	480	10	in	in	IN
cord-009417-458rrhcm	480	11	the	the	DT
cord-009417-458rrhcm	480	12	host	host	NN
cord-009417-458rrhcm	480	13	's	's	POS
cord-009417-458rrhcm	480	14	tissues	tissue	NNS
cord-009417-458rrhcm	480	15	,	,	,
cord-009417-458rrhcm	480	16	particularly	particularly	RB
cord-009417-458rrhcm	480	17	leukocytes	leukocyte	NNS
cord-009417-458rrhcm	480	18	,	,	,
cord-009417-458rrhcm	480	19	and	and	CC
cord-009417-458rrhcm	480	20	is	be	VBZ
cord-009417-458rrhcm	480	21	transmitted	transmit	VBN
cord-009417-458rrhcm	480	22	by	by	IN
cord-009417-458rrhcm	480	23	all	all	DT
cord-009417-458rrhcm	480	24	cellular	cellular	JJ
cord-009417-458rrhcm	480	25	blood	blood	NN
cord-009417-458rrhcm	480	26	components	component	NNS
cord-009417-458rrhcm	480	27	.	.	.
cord-009417-458rrhcm	481	1	108	108	CD
cord-009417-458rrhcm	481	2	Seropositivity	Seropositivity	NNP
cord-009417-458rrhcm	481	3	,	,	,
cord-009417-458rrhcm	481	4	or	or	CC
cord-009417-458rrhcm	481	5	the	the	DT
cord-009417-458rrhcm	481	6	presence	presence	NN
cord-009417-458rrhcm	481	7	of	of	IN
cord-009417-458rrhcm	481	8	antibody	antibody	NN
cord-009417-458rrhcm	481	9	,	,	,
cord-009417-458rrhcm	481	10	denotes	denote	VBZ
cord-009417-458rrhcm	481	11	previous	previous	JJ
cord-009417-458rrhcm	481	12	exposure	exposure	NN
cord-009417-458rrhcm	481	13	to	to	IN
cord-009417-458rrhcm	481	14	the	the	DT
cord-009417-458rrhcm	481	15	virus	virus	NN
cord-009417-458rrhcm	481	16	but	but	CC
cord-009417-458rrhcm	481	17	does	do	VBZ
cord-009417-458rrhcm	481	18	not	not	RB
cord-009417-458rrhcm	481	19	confer	confer	VB
cord-009417-458rrhcm	481	20	protective	protective	JJ
cord-009417-458rrhcm	481	21	immunity	immunity	NN
cord-009417-458rrhcm	481	22	.	.	.
cord-009417-458rrhcm	482	1	Secondary	secondary	JJ
cord-009417-458rrhcm	482	2	reinfection	reinfection	NN
cord-009417-458rrhcm	482	3	or	or	CC
cord-009417-458rrhcm	482	4	reactivation	reactivation	NN
cord-009417-458rrhcm	482	5	of	of	IN
cord-009417-458rrhcm	482	6	latent	latent	JJ
cord-009417-458rrhcm	482	7	infection	infection	NN
cord-009417-458rrhcm	482	8	can	can	MD
cord-009417-458rrhcm	482	9	occur	occur	VB
cord-009417-458rrhcm	482	10	.	.	.
cord-009417-458rrhcm	483	1	Antibodies	antibody	NNS
cord-009417-458rrhcm	483	2	to	to	IN
cord-009417-458rrhcm	483	3	CMV	CMV	NNP
cord-009417-458rrhcm	483	4	persist	persist	VB
cord-009417-458rrhcm	483	5	for	for	IN
cord-009417-458rrhcm	483	6	life	life	NN
cord-009417-458rrhcm	483	7	and	and	CC
cord-009417-458rrhcm	483	8	serve	serve	VB
cord-009417-458rrhcm	483	9	as	as	IN
cord-009417-458rrhcm	483	10	a	a	DT
cord-009417-458rrhcm	483	11	marker	marker	NN
cord-009417-458rrhcm	483	12	indicating	indicate	VBG
cord-009417-458rrhcm	483	13	the	the	DT
cord-009417-458rrhcm	483	14	potential	potential	NN
cord-009417-458rrhcm	483	15	for	for	IN
cord-009417-458rrhcm	483	16	transmission	transmission	NN
cord-009417-458rrhcm	483	17	of	of	IN
cord-009417-458rrhcm	483	18	live	live	JJ
cord-009417-458rrhcm	483	19	virus	virus	NN
cord-009417-458rrhcm	483	20	.	.	.
cord-009417-458rrhcm	484	1	Immunocompetent	Immunocompetent	NNP
cord-009417-458rrhcm	484	2	recipients	recipient	NNS
cord-009417-458rrhcm	484	3	of	of	IN
cord-009417-458rrhcm	484	4	transfused	transfuse	VBN
cord-009417-458rrhcm	484	5	CMVpositive	CMVpositive	NNP
cord-009417-458rrhcm	484	6	blood	blood	NN
cord-009417-458rrhcm	484	7	experience	experience	NN
cord-009417-458rrhcm	484	8	minimal	minimal	JJ
cord-009417-458rrhcm	484	9	morbidity	morbidity	NN
cord-009417-458rrhcm	484	10	and	and	CC
cord-009417-458rrhcm	484	11	mortality	mortality	NN
cord-009417-458rrhcm	484	12	.	.	.
cord-009417-458rrhcm	485	1	The	the	DT
cord-009417-458rrhcm	485	2	majority	majority	NN
cord-009417-458rrhcm	485	3	are	be	VBP
cord-009417-458rrhcm	485	4	asymptomatic	asymptomatic	JJ
cord-009417-458rrhcm	485	5	,	,	,
cord-009417-458rrhcm	485	6	whereas	whereas	IN
cord-009417-458rrhcm	485	7	a	a	DT
cord-009417-458rrhcm	485	8	heterophile	heterophile	NN
cord-009417-458rrhcm	485	9	-	-	HYPH
cord-009417-458rrhcm	485	10	negative	negative	JJ
cord-009417-458rrhcm	485	11	mononucleosis	mononucleosis	NN
cord-009417-458rrhcm	485	12	syndrome	syndrome	NN
cord-009417-458rrhcm	485	13	may	may	MD
cord-009417-458rrhcm	485	14	develop	develop	VB
cord-009417-458rrhcm	485	15	in	in	IN
cord-009417-458rrhcm	485	16	a	a	DT
cord-009417-458rrhcm	485	17	few	few	JJ
cord-009417-458rrhcm	485	18	.	.	.
cord-009417-458rrhcm	486	1	Immunocompromised	immunocompromise	VBN
cord-009417-458rrhcm	486	2	patients	patient	NNS
cord-009417-458rrhcm	486	3	,	,	,
cord-009417-458rrhcm	486	4	however	however	RB
cord-009417-458rrhcm	486	5	,	,	,
cord-009417-458rrhcm	486	6	may	may	MD
cord-009417-458rrhcm	486	7	suffer	suffer	VB
cord-009417-458rrhcm	486	8	life	life	NN
cord-009417-458rrhcm	486	9	-	-	HYPH
cord-009417-458rrhcm	486	10	threatening	threaten	VBG
cord-009417-458rrhcm	486	11	manifestations	manifestation	NNS
cord-009417-458rrhcm	486	12	such	such	JJ
cord-009417-458rrhcm	486	13	as	as	IN
cord-009417-458rrhcm	486	14	severe	severe	JJ
cord-009417-458rrhcm	486	15	interstitial	interstitial	JJ
cord-009417-458rrhcm	486	16	pneumonitis	pneumonitis	NN
cord-009417-458rrhcm	486	17	,	,	,
cord-009417-458rrhcm	486	18	gastroenteritis	gastroenteritis	NN
cord-009417-458rrhcm	486	19	,	,	,
cord-009417-458rrhcm	486	20	hepatitis	hepatitis	NN
cord-009417-458rrhcm	486	21	,	,	,
cord-009417-458rrhcm	486	22	or	or	CC
cord-009417-458rrhcm	486	23	disseminated	disseminate	VBN
cord-009417-458rrhcm	486	24	disease	disease	NN
cord-009417-458rrhcm	486	25	.	.	.
cord-009417-458rrhcm	487	1	Several	several	JJ
cord-009417-458rrhcm	487	2	groups	group	NNS
cord-009417-458rrhcm	487	3	of	of	IN
cord-009417-458rrhcm	487	4	patients	patient	NNS
cord-009417-458rrhcm	487	5	are	be	VBP
cord-009417-458rrhcm	487	6	at	at	IN
cord-009417-458rrhcm	487	7	particular	particular	JJ
cord-009417-458rrhcm	487	8	risk	risk	NN
cord-009417-458rrhcm	487	9	(	(	-LRB-
cord-009417-458rrhcm	487	10	Box	Box	NNP
cord-009417-458rrhcm	487	11	80	80	CD
cord-009417-458rrhcm	487	12	-	-	SYM
cord-009417-458rrhcm	487	13	1	1	CD
cord-009417-458rrhcm	487	14	)	)	-RRB-
cord-009417-458rrhcm	487	15	,	,	,
cord-009417-458rrhcm	487	16	109	109	CD
cord-009417-458rrhcm	487	17	and	and	CC
cord-009417-458rrhcm	487	18	these	these	DT
cord-009417-458rrhcm	487	19	patients	patient	NNS
cord-009417-458rrhcm	487	20	should	should	MD
cord-009417-458rrhcm	487	21	receive	receive	VB
cord-009417-458rrhcm	487	22	blood	blood	NN
cord-009417-458rrhcm	487	23	incapable	incapable	JJ
cord-009417-458rrhcm	487	24	of	of	IN
cord-009417-458rrhcm	487	25	transmitting	transmit	VBG
cord-009417-458rrhcm	487	26	the	the	DT
cord-009417-458rrhcm	487	27	virus	virus	NN
cord-009417-458rrhcm	487	28	.	.	.
cord-009417-458rrhcm	488	1	Other	other	JJ
cord-009417-458rrhcm	488	2	patients	patient	NNS
cord-009417-458rrhcm	488	3	may	may	MD
cord-009417-458rrhcm	488	4	benefi	benefi	VB
cord-009417-458rrhcm	488	5	t	t	NN
cord-009417-458rrhcm	488	6	from	from	IN
cord-009417-458rrhcm	488	7	CMV	CMV	NNP
cord-009417-458rrhcm	488	8	-	-	HYPH
cord-009417-458rrhcm	488	9	negative	negative	JJ
cord-009417-458rrhcm	488	10	blood	blood	NN
cord-009417-458rrhcm	488	11	as	as	RB
cord-009417-458rrhcm	488	12	well	well	RB
cord-009417-458rrhcm	488	13	,	,	,
cord-009417-458rrhcm	488	14	such	such	JJ
cord-009417-458rrhcm	488	15	as	as	IN
cord-009417-458rrhcm	488	16	seronegative	seronegative	JJ
cord-009417-458rrhcm	488	17	solid	solid	JJ
cord-009417-458rrhcm	488	18	organ	organ	NN
cord-009417-458rrhcm	488	19	transplant	transplant	NN
cord-009417-458rrhcm	488	20	recipients	recipient	NNS
cord-009417-458rrhcm	488	21	or	or	CC
cord-009417-458rrhcm	488	22	autologous	autologous	JJ
cord-009417-458rrhcm	488	23	BMT	BMT	NNP
cord-009417-458rrhcm	488	24	patients	patient	NNS
cord-009417-458rrhcm	488	25	.	.	.
cord-009417-458rrhcm	489	1	Screening	screening	NN
cord-009417-458rrhcm	489	2	of	of	IN
cord-009417-458rrhcm	489	3	donated	donate	VBN
cord-009417-458rrhcm	489	4	blood	blood	NN
cord-009417-458rrhcm	489	5	for	for	IN
cord-009417-458rrhcm	489	6	CMV	CMV	NNP
cord-009417-458rrhcm	489	7	is	be	VBZ
cord-009417-458rrhcm	489	8	not	not	RB
cord-009417-458rrhcm	489	9	routinely	routinely	RB
cord-009417-458rrhcm	489	10	done	do	VBN
cord-009417-458rrhcm	489	11	but	but	CC
cord-009417-458rrhcm	489	12	can	can	MD
cord-009417-458rrhcm	489	13	be	be	VB
cord-009417-458rrhcm	489	14	performed	perform	VBN
cord-009417-458rrhcm	489	15	quickly	quickly	RB
cord-009417-458rrhcm	489	16	if	if	IN
cord-009417-458rrhcm	489	17	necessary	necessary	JJ
cord-009417-458rrhcm	489	18	.	.	.
cord-009417-458rrhcm	490	1	Because	because	IN
cord-009417-458rrhcm	490	2	the	the	DT
cord-009417-458rrhcm	490	3	prevalence	prevalence	NN
cord-009417-458rrhcm	490	4	of	of	IN
cord-009417-458rrhcm	490	5	donor	donor	NN
cord-009417-458rrhcm	490	6	seropositivity	seropositivity	NN
cord-009417-458rrhcm	490	7	is	be	VBZ
cord-009417-458rrhcm	490	8	quite	quite	RB
cord-009417-458rrhcm	490	9	high	high	JJ
cord-009417-458rrhcm	490	10	in	in	IN
cord-009417-458rrhcm	490	11	some	some	DT
cord-009417-458rrhcm	490	12	regions	region	NNS
cord-009417-458rrhcm	490	13	(	(	-LRB-
cord-009417-458rrhcm	490	14	50	50	CD
cord-009417-458rrhcm	490	15	%	%	NN
cord-009417-458rrhcm	490	16	to	to	TO
cord-009417-458rrhcm	490	17	70	70	CD
cord-009417-458rrhcm	490	18	%	%	NN
cord-009417-458rrhcm	490	19	)	)	-RRB-
cord-009417-458rrhcm	490	20	,	,	,
cord-009417-458rrhcm	490	21	CMVseronegative	cmvseronegative	JJ
cord-009417-458rrhcm	490	22	blood	blood	NN
cord-009417-458rrhcm	490	23	may	may	MD
cord-009417-458rrhcm	490	24	not	not	RB
cord-009417-458rrhcm	490	25	be	be	VB
cord-009417-458rrhcm	490	26	readily	readily	RB
cord-009417-458rrhcm	490	27	available	available	JJ
cord-009417-458rrhcm	490	28	.	.	.
cord-009417-458rrhcm	491	1	Blood	blood	NN
cord-009417-458rrhcm	491	2	that	that	WDT
cord-009417-458rrhcm	491	3	is	be	VBZ
cord-009417-458rrhcm	491	4	leukocyte	leukocyte	NN
cord-009417-458rrhcm	491	5	depleted	deplete	VBN
cord-009417-458rrhcm	492	1	(	(	-LRB-
cord-009417-458rrhcm	492	2	"	"	``
cord-009417-458rrhcm	492	3	CMV	CMV	NNP
cord-009417-458rrhcm	492	4	safe	safe	JJ
cord-009417-458rrhcm	492	5	"	"	''
cord-009417-458rrhcm	492	6	)	)	-RRB-
cord-009417-458rrhcm	492	7	may	may	MD
cord-009417-458rrhcm	492	8	be	be	VB
cord-009417-458rrhcm	492	9	as	as	RB
cord-009417-458rrhcm	492	10	effective	effective	JJ
cord-009417-458rrhcm	492	11	as	as	IN
cord-009417-458rrhcm	492	12	seronegative	seronegative	JJ
cord-009417-458rrhcm	492	13	blood	blood	NN
cord-009417-458rrhcm	492	14	in	in	IN
cord-009417-458rrhcm	492	15	the	the	DT
cord-009417-458rrhcm	492	16	prevention	prevention	NN
cord-009417-458rrhcm	492	17	of	of	IN
cord-009417-458rrhcm	492	18	CMV	CMV	NNP
cord-009417-458rrhcm	492	19	transmission	transmission	NN
cord-009417-458rrhcm	492	20	,	,	,
cord-009417-458rrhcm	492	21	although	although	IN
cord-009417-458rrhcm	492	22	a	a	DT
cord-009417-458rrhcm	492	23	recent	recent	JJ
cord-009417-458rrhcm	492	24	meta	meta	JJ
cord-009417-458rrhcm	492	25	-	-	HYPH
cord-009417-458rrhcm	492	26	analysis	analysis	NN
cord-009417-458rrhcm	492	27	of	of	IN
cord-009417-458rrhcm	492	28	clinical	clinical	JJ
cord-009417-458rrhcm	492	29	trials	trial	NNS
cord-009417-458rrhcm	492	30	comparing	compare	VBG
cord-009417-458rrhcm	492	31	the	the	DT
cord-009417-458rrhcm	492	32	two	two	CD
cord-009417-458rrhcm	492	33	methods	method	NNS
cord-009417-458rrhcm	492	34	suggests	suggest	VBZ
cord-009417-458rrhcm	492	35	that	that	IN
cord-009417-458rrhcm	492	36	CMVnegative	cmvnegative	JJ
cord-009417-458rrhcm	492	37	blood	blood	NN
cord-009417-458rrhcm	492	38	products	product	NNS
cord-009417-458rrhcm	492	39	might	may	MD
cord-009417-458rrhcm	492	40	have	have	VB
cord-009417-458rrhcm	492	41	a	a	DT
cord-009417-458rrhcm	492	42	slight	slight	JJ
cord-009417-458rrhcm	492	43	advantage	advantage	NN
cord-009417-458rrhcm	492	44	over	over	IN
cord-009417-458rrhcm	492	45	leukocyte	leukocyte	NN
cord-009417-458rrhcm	492	46	-	-	HYPH
cord-009417-458rrhcm	492	47	depleted	deplete	VBN
cord-009417-458rrhcm	492	48	products	product	NNS
cord-009417-458rrhcm	492	49	.	.	.
cord-009417-458rrhcm	493	1	110	110	CD
cord-009417-458rrhcm	494	1	Many	many	JJ
cord-009417-458rrhcm	494	2	blood	blood	NN
cord-009417-458rrhcm	494	3	-	-	HYPH
cord-009417-458rrhcm	494	4	borne	bear	VBN
cord-009417-458rrhcm	494	5	parasites	parasite	NNS
cord-009417-458rrhcm	494	6	may	may	MD
cord-009417-458rrhcm	494	7	be	be	VB
cord-009417-458rrhcm	494	8	transmitted	transmit	VBN
cord-009417-458rrhcm	494	9	by	by	IN
cord-009417-458rrhcm	494	10	transfusion	transfusion	NN
cord-009417-458rrhcm	494	11	,	,	,
cord-009417-458rrhcm	494	12	although	although	IN
cord-009417-458rrhcm	494	13	this	this	DT
cord-009417-458rrhcm	494	14	is	be	VBZ
cord-009417-458rrhcm	494	15	a	a	DT
cord-009417-458rrhcm	494	16	rare	rare	JJ
cord-009417-458rrhcm	494	17	occurrence	occurrence	NN
cord-009417-458rrhcm	494	18	in	in	IN
cord-009417-458rrhcm	494	19	the	the	DT
cord-009417-458rrhcm	494	20	United	United	NNP
cord-009417-458rrhcm	494	21	States	States	NNP
cord-009417-458rrhcm	494	22	because	because	IN
cord-009417-458rrhcm	494	23	of	of	IN
cord-009417-458rrhcm	494	24	donor	donor	NN
cord-009417-458rrhcm	494	25	screening	screening	NN
cord-009417-458rrhcm	494	26	questions	question	NNS
cord-009417-458rrhcm	494	27	and	and	CC
cord-009417-458rrhcm	494	28	the	the	DT
cord-009417-458rrhcm	494	29	low	low	JJ
cord-009417-458rrhcm	494	30	endemicity	endemicity	NN
cord-009417-458rrhcm	494	31	of	of	IN
cord-009417-458rrhcm	494	32	implicated	implicate	VBN
cord-009417-458rrhcm	494	33	agents	agent	NNS
cord-009417-458rrhcm	494	34	.	.	.
cord-009417-458rrhcm	495	1	111	111	CD
cord-009417-458rrhcm	496	1	Changing	change	VBG
cord-009417-458rrhcm	496	2	immigration	immigration	NN
cord-009417-458rrhcm	496	3	patterns	pattern	NNS
cord-009417-458rrhcm	496	4	and	and	CC
cord-009417-458rrhcm	496	5	worldwide	worldwide	JJ
cord-009417-458rrhcm	496	6	travel	travel	NN
cord-009417-458rrhcm	496	7	,	,	,
cord-009417-458rrhcm	496	8	however	however	RB
cord-009417-458rrhcm	496	9	,	,	,
cord-009417-458rrhcm	496	10	make	make	VBP
cord-009417-458rrhcm	496	11	transfusion	transfusion	NN
cord-009417-458rrhcm	496	12	-	-	HYPH
cord-009417-458rrhcm	496	13	transmitted	transmit	VBN
cord-009417-458rrhcm	496	14	parasites	parasite	NNS
cord-009417-458rrhcm	496	15	an	an	DT
cord-009417-458rrhcm	496	16	increasing	increase	VBG
cord-009417-458rrhcm	496	17	concern	concern	NN
cord-009417-458rrhcm	496	18	.	.	.
cord-009417-458rrhcm	497	1	On	on	IN
cord-009417-458rrhcm	497	2	a	a	DT
cord-009417-458rrhcm	497	3	worldwide	worldwide	JJ
cord-009417-458rrhcm	497	4	basis	basis	NN
cord-009417-458rrhcm	497	5	,	,	,
cord-009417-458rrhcm	497	6	malaria	malaria	NN
cord-009417-458rrhcm	497	7	is	be	VBZ
cord-009417-458rrhcm	497	8	the	the	DT
cord-009417-458rrhcm	497	9	most	most	RBS
cord-009417-458rrhcm	497	10	important	important	JJ
cord-009417-458rrhcm	497	11	transfusion	transfusion	NN
cord-009417-458rrhcm	497	12	-	-	HYPH
cord-009417-458rrhcm	497	13	transmitted	transmit	VBN
cord-009417-458rrhcm	497	14	infective	infective	JJ
cord-009417-458rrhcm	497	15	organism	organism	NN
cord-009417-458rrhcm	497	16	,	,	,
cord-009417-458rrhcm	497	17	although	although	IN
cord-009417-458rrhcm	497	18	only	only	RB
cord-009417-458rrhcm	497	19	about	about	RB
cord-009417-458rrhcm	497	20	three	three	CD
cord-009417-458rrhcm	497	21	cases	case	NNS
cord-009417-458rrhcm	497	22	occur	occur	VBP
cord-009417-458rrhcm	497	23	in	in	IN
cord-009417-458rrhcm	497	24	the	the	DT
cord-009417-458rrhcm	497	25	United	United	NNP
cord-009417-458rrhcm	497	26	States	States	NNP
cord-009417-458rrhcm	497	27	each	each	DT
cord-009417-458rrhcm	497	28	year	year	NN
cord-009417-458rrhcm	497	29	.	.	.
cord-009417-458rrhcm	498	1	Such	such	JJ
cord-009417-458rrhcm	498	2	infections	infection	NNS
cord-009417-458rrhcm	498	3	are	be	VBP
cord-009417-458rrhcm	498	4	manifested	manifest	VBN
cord-009417-458rrhcm	498	5	by	by	IN
cord-009417-458rrhcm	498	6	delayed	delay	VBN
cord-009417-458rrhcm	498	7	fever	fever	NN
cord-009417-458rrhcm	498	8	,	,	,
cord-009417-458rrhcm	498	9	chills	chill	NNS
cord-009417-458rrhcm	498	10	,	,	,
cord-009417-458rrhcm	498	11	Seronegative	seronegative	JJ
cord-009417-458rrhcm	498	12	pregnant	pregnant	JJ
cord-009417-458rrhcm	498	13	women	woman	NNS
cord-009417-458rrhcm	498	14	Seronegative	seronegative	JJ
cord-009417-458rrhcm	498	15	premature	premature	JJ
cord-009417-458rrhcm	498	16	infants	infant	NNS
cord-009417-458rrhcm	498	17	weighing	weigh	VBG
cord-009417-458rrhcm	498	18	less	less	JJR
cord-009417-458rrhcm	498	19	than	than	IN
cord-009417-458rrhcm	498	20	1200	1200	CD
cord-009417-458rrhcm	498	21	g	g	NN
cord-009417-458rrhcm	498	22	Seronegative	seronegative	JJ
cord-009417-458rrhcm	498	23	allogeneic	allogeneic	NN
cord-009417-458rrhcm	498	24	or	or	CC
cord-009417-458rrhcm	498	25	autologous	autologous	JJ
cord-009417-458rrhcm	498	26	bone	bone	NN
cord-009417-458rrhcm	498	27	marrow	marrow	NN
cord-009417-458rrhcm	498	28	transplant	transplant	NN
cord-009417-458rrhcm	498	29	recipients	recipient	NNS
cord-009417-458rrhcm	498	30	Seronegative	seronegative	JJ
cord-009417-458rrhcm	498	31	transplant	transplant	NN
cord-009417-458rrhcm	498	32	recipients	recipient	NNS
cord-009417-458rrhcm	498	33	of	of	IN
cord-009417-458rrhcm	498	34	seronegative	seronegative	JJ
cord-009417-458rrhcm	498	35	organs	organ	NNS
cord-009417-458rrhcm	498	36	diaphoresis	diaphoresis	NN
cord-009417-458rrhcm	498	37	,	,	,
cord-009417-458rrhcm	498	38	and	and	CC
cord-009417-458rrhcm	498	39	hemolysis	hemolysis	NN
cord-009417-458rrhcm	498	40	,	,	,
cord-009417-458rrhcm	498	41	often	often	RB
cord-009417-458rrhcm	498	42	masked	mask	VBN
cord-009417-458rrhcm	498	43	by	by	IN
cord-009417-458rrhcm	498	44	underlying	underlie	VBG
cord-009417-458rrhcm	498	45	medical	medical	JJ
cord-009417-458rrhcm	498	46	conditions	condition	NNS
cord-009417-458rrhcm	498	47	.	.	.
cord-009417-458rrhcm	499	1	Fatalities	fatality	NNS
cord-009417-458rrhcm	499	2	have	have	VBP
cord-009417-458rrhcm	499	3	occurred	occur	VBN
cord-009417-458rrhcm	499	4	.	.	.
cord-009417-458rrhcm	500	1	Babesiosis	babesiosis	NN
cord-009417-458rrhcm	500	2	,	,	,
cord-009417-458rrhcm	500	3	a	a	DT
cord-009417-458rrhcm	500	4	tick	tick	NN
cord-009417-458rrhcm	500	5	-	-	HYPH
cord-009417-458rrhcm	500	6	borne	bear	VBN
cord-009417-458rrhcm	500	7	disease	disease	NN
cord-009417-458rrhcm	500	8	,	,	,
cord-009417-458rrhcm	500	9	is	be	VBZ
cord-009417-458rrhcm	500	10	endemic	endemic	JJ
cord-009417-458rrhcm	500	11	in	in	IN
cord-009417-458rrhcm	500	12	regions	region	NNS
cord-009417-458rrhcm	500	13	of	of	IN
cord-009417-458rrhcm	500	14	the	the	DT
cord-009417-458rrhcm	500	15	United	United	NNP
cord-009417-458rrhcm	500	16	States	States	NNP
cord-009417-458rrhcm	500	17	,	,	,
cord-009417-458rrhcm	500	18	especially	especially	RB
cord-009417-458rrhcm	500	19	the	the	DT
cord-009417-458rrhcm	500	20	northeast	northeast	NN
cord-009417-458rrhcm	500	21	,	,	,
cord-009417-458rrhcm	500	22	with	with	IN
cord-009417-458rrhcm	500	23	a	a	DT
cord-009417-458rrhcm	500	24	seroprevalence	seroprevalence	NN
cord-009417-458rrhcm	500	25	of	of	IN
cord-009417-458rrhcm	500	26	about	about	IN
cord-009417-458rrhcm	500	27	4	4	CD
cord-009417-458rrhcm	500	28	%	%	NN
cord-009417-458rrhcm	500	29	.	.	.
cord-009417-458rrhcm	501	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	501	2	-	-	HYPH
cord-009417-458rrhcm	501	3	transmitted	transmit	VBN
cord-009417-458rrhcm	501	4	cases	case	NNS
cord-009417-458rrhcm	501	5	have	have	VBP
cord-009417-458rrhcm	501	6	been	be	VBN
cord-009417-458rrhcm	501	7	reported	report	VBN
cord-009417-458rrhcm	501	8	,	,	,
cord-009417-458rrhcm	501	9	with	with	IN
cord-009417-458rrhcm	501	10	asplenic	asplenic	NNP
cord-009417-458rrhcm	501	11	or	or	CC
cord-009417-458rrhcm	501	12	immunocompromised	immunocompromised	JJ
cord-009417-458rrhcm	501	13	patients	patient	NNS
cord-009417-458rrhcm	501	14	being	be	VBG
cord-009417-458rrhcm	501	15	particularly	particularly	RB
cord-009417-458rrhcm	501	16	susceptible	susceptible	JJ
cord-009417-458rrhcm	501	17	.	.	.
cord-009417-458rrhcm	502	1	With	with	IN
cord-009417-458rrhcm	502	2	increases	increase	NNS
cord-009417-458rrhcm	502	3	in	in	IN
cord-009417-458rrhcm	502	4	the	the	DT
cord-009417-458rrhcm	502	5	number	number	NN
cord-009417-458rrhcm	502	6	of	of	IN
cord-009417-458rrhcm	502	7	Latin	latin	JJ
cord-009417-458rrhcm	502	8	American	american	JJ
cord-009417-458rrhcm	502	9	immigrants	immigrant	NNS
cord-009417-458rrhcm	502	10	to	to	IN
cord-009417-458rrhcm	502	11	the	the	DT
cord-009417-458rrhcm	502	12	United	United	NNP
cord-009417-458rrhcm	502	13	States	States	NNP
cord-009417-458rrhcm	502	14	,	,	,
cord-009417-458rrhcm	502	15	American	american	JJ
cord-009417-458rrhcm	502	16	trypanosomiasis	trypanosomiasis	NN
cord-009417-458rrhcm	502	17	(	(	-LRB-
cord-009417-458rrhcm	502	18	Chagas	Chagas	NNP
cord-009417-458rrhcm	502	19	'	'	POS
cord-009417-458rrhcm	502	20	disease	disease	NN
cord-009417-458rrhcm	502	21	)	)	-RRB-
cord-009417-458rrhcm	502	22	,	,	,
cord-009417-458rrhcm	502	23	which	which	WDT
cord-009417-458rrhcm	502	24	is	be	VBZ
cord-009417-458rrhcm	502	25	endemic	endemic	JJ
cord-009417-458rrhcm	502	26	in	in	IN
cord-009417-458rrhcm	502	27	Latin	latin	JJ
cord-009417-458rrhcm	502	28	American	american	JJ
cord-009417-458rrhcm	502	29	countries	country	NNS
cord-009417-458rrhcm	502	30	,	,	,
cord-009417-458rrhcm	502	31	has	have	VBZ
cord-009417-458rrhcm	502	32	emerged	emerge	VBN
cord-009417-458rrhcm	502	33	as	as	IN
cord-009417-458rrhcm	502	34	a	a	DT
cord-009417-458rrhcm	502	35	potential	potential	JJ
cord-009417-458rrhcm	502	36	pathogen	pathogen	NN
cord-009417-458rrhcm	502	37	.	.	.
cord-009417-458rrhcm	503	1	Other	other	JJ
cord-009417-458rrhcm	503	2	parasitic	parasitic	JJ
cord-009417-458rrhcm	503	3	diseases	disease	NNS
cord-009417-458rrhcm	503	4	that	that	WDT
cord-009417-458rrhcm	503	5	have	have	VBP
cord-009417-458rrhcm	503	6	been	be	VBN
cord-009417-458rrhcm	503	7	transmitted	transmit	VBN
cord-009417-458rrhcm	503	8	by	by	IN
cord-009417-458rrhcm	503	9	transfusion	transfusion	NN
cord-009417-458rrhcm	503	10	include	include	VBP
cord-009417-458rrhcm	503	11	toxoplasmosis	toxoplasmosis	NN
cord-009417-458rrhcm	503	12	,	,	,
cord-009417-458rrhcm	503	13	leishmaniasis	leishmaniasis	NN
cord-009417-458rrhcm	503	14	,	,	,
cord-009417-458rrhcm	503	15	and	and	CC
cord-009417-458rrhcm	503	16	Lyme	Lyme	NNP
cord-009417-458rrhcm	503	17	disease	disease	NN
cord-009417-458rrhcm	503	18	.	.	.
cord-009417-458rrhcm	504	1	Parvovirus	Parvovirus	NNP
cord-009417-458rrhcm	504	2	B19	B19	NNP
cord-009417-458rrhcm	504	3	has	have	VBZ
cord-009417-458rrhcm	504	4	now	now	RB
cord-009417-458rrhcm	504	5	been	be	VBN
cord-009417-458rrhcm	504	6	recognized	recognize	VBN
cord-009417-458rrhcm	504	7	as	as	IN
cord-009417-458rrhcm	504	8	a	a	DT
cord-009417-458rrhcm	504	9	pathogen	pathogen	NN
cord-009417-458rrhcm	504	10	capable	capable	JJ
cord-009417-458rrhcm	504	11	of	of	IN
cord-009417-458rrhcm	504	12	transmission	transmission	NN
cord-009417-458rrhcm	504	13	by	by	IN
cord-009417-458rrhcm	504	14	transfusion	transfusion	NN
cord-009417-458rrhcm	504	15	,	,	,
cord-009417-458rrhcm	504	16	with	with	IN
cord-009417-458rrhcm	504	17	typical	typical	JJ
cord-009417-458rrhcm	504	18	clinical	clinical	JJ
cord-009417-458rrhcm	504	19	fi	fi	NN
cord-009417-458rrhcm	504	20	ndings	nding	NNS
cord-009417-458rrhcm	504	21	and	and	CC
cord-009417-458rrhcm	504	22	the	the	DT
cord-009417-458rrhcm	504	23	potential	potential	NN
cord-009417-458rrhcm	504	24	for	for	IN
cord-009417-458rrhcm	504	25	severe	severe	JJ
cord-009417-458rrhcm	504	26	hematologic	hematologic	JJ
cord-009417-458rrhcm	504	27	complications	complication	NNS
cord-009417-458rrhcm	504	28	.	.	.
cord-009417-458rrhcm	505	1	Cases	case	NNS
cord-009417-458rrhcm	505	2	of	of	IN
cord-009417-458rrhcm	505	3	Epstein	Epstein	NNP
cord-009417-458rrhcm	505	4	-	-	HYPH
cord-009417-458rrhcm	505	5	Barr	Barr	NNP
cord-009417-458rrhcm	505	6	virus	virus	NN
cord-009417-458rrhcm	505	7	infection	infection	NN
cord-009417-458rrhcm	505	8	with	with	IN
cord-009417-458rrhcm	505	9	a	a	DT
cord-009417-458rrhcm	505	10	typical	typical	JJ
cord-009417-458rrhcm	505	11	mononucleosis	mononucleosis	NN
cord-009417-458rrhcm	505	12	-	-	HYPH
cord-009417-458rrhcm	505	13	like	like	JJ
cord-009417-458rrhcm	505	14	illness	illness	NN
cord-009417-458rrhcm	505	15	have	have	VBP
cord-009417-458rrhcm	505	16	been	be	VBN
cord-009417-458rrhcm	505	17	reported	report	VBN
cord-009417-458rrhcm	505	18	after	after	IN
cord-009417-458rrhcm	505	19	transfusion	transfusion	NN
cord-009417-458rrhcm	505	20	.	.	.
cord-009417-458rrhcm	506	1	West	West	NNP
cord-009417-458rrhcm	506	2	Nile	Nile	NNP
cord-009417-458rrhcm	506	3	virus	virus	NN
cord-009417-458rrhcm	506	4	has	have	VBZ
cord-009417-458rrhcm	506	5	also	also	RB
cord-009417-458rrhcm	506	6	been	be	VBN
cord-009417-458rrhcm	506	7	transmitted	transmit	VBN
cord-009417-458rrhcm	506	8	by	by	IN
cord-009417-458rrhcm	506	9	transfusion	transfusion	NN
cord-009417-458rrhcm	506	10	.	.	.
cord-009417-458rrhcm	507	1	H2N1	H2N1	NNP
cord-009417-458rrhcm	507	2	infl	infl	NNP
cord-009417-458rrhcm	507	3	uenza	uenza	NNP
cord-009417-458rrhcm	507	4	,	,	,
cord-009417-458rrhcm	507	5	severe	severe	JJ
cord-009417-458rrhcm	507	6	acute	acute	JJ
cord-009417-458rrhcm	507	7	respiratory	respiratory	JJ
cord-009417-458rrhcm	507	8	syndrome	syndrome	NN
cord-009417-458rrhcm	507	9	(	(	-LRB-
cord-009417-458rrhcm	507	10	SARS	SARS	NNP
cord-009417-458rrhcm	507	11	)	)	-RRB-
cord-009417-458rrhcm	507	12	,	,	,
cord-009417-458rrhcm	507	13	and	and	CC
cord-009417-458rrhcm	507	14	other	other	JJ
cord-009417-458rrhcm	507	15	new	new	JJ
cord-009417-458rrhcm	507	16	viral	viral	JJ
cord-009417-458rrhcm	507	17	infections	infection	NNS
cord-009417-458rrhcm	507	18	should	should	MD
cord-009417-458rrhcm	507	19	be	be	VB
cord-009417-458rrhcm	507	20	capable	capable	JJ
cord-009417-458rrhcm	507	21	of	of	IN
cord-009417-458rrhcm	507	22	transmission	transmission	NN
cord-009417-458rrhcm	507	23	by	by	IN
cord-009417-458rrhcm	507	24	transfusion	transfusion	NN
cord-009417-458rrhcm	507	25	,	,	,
cord-009417-458rrhcm	507	26	although	although	IN
cord-009417-458rrhcm	507	27	cases	case	NNS
cord-009417-458rrhcm	507	28	have	have	VBP
cord-009417-458rrhcm	507	29	not	not	RB
cord-009417-458rrhcm	507	30	been	be	VBN
cord-009417-458rrhcm	507	31	reported	report	VBN
cord-009417-458rrhcm	507	32	and	and	CC
cord-009417-458rrhcm	507	33	the	the	DT
cord-009417-458rrhcm	507	34	prevalence	prevalence	NN
cord-009417-458rrhcm	507	35	of	of	IN
cord-009417-458rrhcm	507	36	asymptomatic	asymptomatic	JJ
cord-009417-458rrhcm	507	37	disease	disease	NN
cord-009417-458rrhcm	507	38	is	be	VBZ
cord-009417-458rrhcm	507	39	unknown	unknown	JJ
cord-009417-458rrhcm	507	40	.	.	.
cord-009417-458rrhcm	508	1	A	a	DT
cord-009417-458rrhcm	508	2	rising	rise	VBG
cord-009417-458rrhcm	508	3	area	area	NN
cord-009417-458rrhcm	508	4	of	of	IN
cord-009417-458rrhcm	508	5	concern	concern	NN
cord-009417-458rrhcm	508	6	is	be	VBZ
cord-009417-458rrhcm	508	7	the	the	DT
cord-009417-458rrhcm	508	8	transmission	transmission	NN
cord-009417-458rrhcm	508	9	of	of	IN
cord-009417-458rrhcm	508	10	prion	prion	NN
cord-009417-458rrhcm	508	11	disease	disease	NN
cord-009417-458rrhcm	508	12	,	,	,
cord-009417-458rrhcm	508	13	either	either	CC
cord-009417-458rrhcm	508	14	Jacob	Jacob	NNP
cord-009417-458rrhcm	508	15	-	-	HYPH
cord-009417-458rrhcm	508	16	Creutzfeldt	Creutzfeldt	NNP
cord-009417-458rrhcm	508	17	disease	disease	NN
cord-009417-458rrhcm	508	18	or	or	CC
cord-009417-458rrhcm	508	19	bovine	bovine	JJ
cord-009417-458rrhcm	508	20	spongiform	spongiform	JJ
cord-009417-458rrhcm	508	21	encephalopathy	encephalopathy	NN
cord-009417-458rrhcm	508	22	(	(	-LRB-
cord-009417-458rrhcm	508	23	BSE	BSE	NNP
cord-009417-458rrhcm	508	24	)	)	-RRB-
cord-009417-458rrhcm	508	25	.	.	.
cord-009417-458rrhcm	509	1	Donor	donor	NN
cord-009417-458rrhcm	509	2	referral	referral	NN
cord-009417-458rrhcm	509	3	criteria	criterion	NNS
cord-009417-458rrhcm	509	4	were	be	VBD
cord-009417-458rrhcm	509	5	implemented	implement	VBN
cord-009417-458rrhcm	509	6	in	in	IN
cord-009417-458rrhcm	509	7	1987	1987	CD
cord-009417-458rrhcm	509	8	for	for	IN
cord-009417-458rrhcm	509	9	these	these	DT
cord-009417-458rrhcm	509	10	diseases	disease	NNS
cord-009417-458rrhcm	509	11	,	,	,
cord-009417-458rrhcm	509	12	and	and	CC
cord-009417-458rrhcm	509	13	transmission	transmission	NN
cord-009417-458rrhcm	509	14	of	of	IN
cord-009417-458rrhcm	509	15	BSE	BSE	NNP
cord-009417-458rrhcm	509	16	has	have	VBZ
cord-009417-458rrhcm	509	17	been	be	VBN
cord-009417-458rrhcm	509	18	reported	report	VBN
cord-009417-458rrhcm	509	19	in	in	IN
cord-009417-458rrhcm	509	20	the	the	DT
cord-009417-458rrhcm	509	21	United	United	NNP
cord-009417-458rrhcm	509	22	Kingdom	Kingdom	NNP
cord-009417-458rrhcm	509	23	.	.	.
cord-009417-458rrhcm	510	1	Massive	massive	JJ
cord-009417-458rrhcm	510	2	transfusion	transfusion	NN
cord-009417-458rrhcm	510	3	is	be	VBZ
cord-009417-458rrhcm	510	4	defi	defi	NNP
cord-009417-458rrhcm	510	5	ned	ned	NNP
cord-009417-458rrhcm	510	6	as	as	IN
cord-009417-458rrhcm	510	7	the	the	DT
cord-009417-458rrhcm	510	8	administration	administration	NN
cord-009417-458rrhcm	510	9	of	of	IN
cord-009417-458rrhcm	510	10	blood	blood	NN
cord-009417-458rrhcm	510	11	components	component	NNS
cord-009417-458rrhcm	510	12	in	in	IN
cord-009417-458rrhcm	510	13	excess	excess	NN
cord-009417-458rrhcm	510	14	of	of	IN
cord-009417-458rrhcm	510	15	one	one	CD
cord-009417-458rrhcm	510	16	blood	blood	NN
cord-009417-458rrhcm	510	17	volume	volume	NN
cord-009417-458rrhcm	510	18	within	within	IN
cord-009417-458rrhcm	510	19	a	a	DT
cord-009417-458rrhcm	510	20	24-hour	24-hour	JJ
cord-009417-458rrhcm	510	21	period	period	NN
cord-009417-458rrhcm	510	22	.	.	.
cord-009417-458rrhcm	511	1	In	in	IN
cord-009417-458rrhcm	511	2	an	an	DT
cord-009417-458rrhcm	511	3	average	average	JJ
cord-009417-458rrhcm	511	4	adult	adult	NN
cord-009417-458rrhcm	511	5	(	(	-LRB-
cord-009417-458rrhcm	511	6	70	70	CD
cord-009417-458rrhcm	511	7	kg	kg	NNS
cord-009417-458rrhcm	511	8	)	)	-RRB-
cord-009417-458rrhcm	511	9	,	,	,
cord-009417-458rrhcm	511	10	this	this	DT
cord-009417-458rrhcm	511	11	represents	represent	VBZ
cord-009417-458rrhcm	511	12	approximately	approximately	RB
cord-009417-458rrhcm	511	13	10	10	CD
cord-009417-458rrhcm	511	14	units	unit	NNS
cord-009417-458rrhcm	511	15	of	of	IN
cord-009417-458rrhcm	511	16	WB	WB	NNP
cord-009417-458rrhcm	511	17	or	or	CC
cord-009417-458rrhcm	511	18	equivalent	equivalent	JJ
cord-009417-458rrhcm	511	19	PRBCs	prbc	NNS
cord-009417-458rrhcm	511	20	,	,	,
cord-009417-458rrhcm	511	21	crystalloid	crystalloid	NN
cord-009417-458rrhcm	511	22	solution	solution	NN
cord-009417-458rrhcm	511	23	,	,	,
cord-009417-458rrhcm	511	24	and	and	CC
cord-009417-458rrhcm	511	25	other	other	JJ
cord-009417-458rrhcm	511	26	components	component	NNS
cord-009417-458rrhcm	511	27	.	.	.
cord-009417-458rrhcm	512	1	Massive	massive	JJ
cord-009417-458rrhcm	512	2	transfusion	transfusion	NN
cord-009417-458rrhcm	512	3	,	,	,
cord-009417-458rrhcm	512	4	especially	especially	RB
cord-009417-458rrhcm	512	5	in	in	IN
cord-009417-458rrhcm	512	6	the	the	DT
cord-009417-458rrhcm	512	7	range	range	NN
cord-009417-458rrhcm	512	8	of	of	IN
cord-009417-458rrhcm	512	9	20	20	CD
cord-009417-458rrhcm	512	10	or	or	CC
cord-009417-458rrhcm	512	11	more	more	JJR
cord-009417-458rrhcm	512	12	units	unit	NNS
cord-009417-458rrhcm	512	13	of	of	IN
cord-009417-458rrhcm	512	14	blood	blood	NN
cord-009417-458rrhcm	512	15	products	product	NNS
cord-009417-458rrhcm	512	16	,	,	,
cord-009417-458rrhcm	512	17	causes	cause	VBZ
cord-009417-458rrhcm	512	18	complications	complication	NNS
cord-009417-458rrhcm	512	19	not	not	RB
cord-009417-458rrhcm	512	20	generally	generally	RB
cord-009417-458rrhcm	512	21	seen	see	VBN
cord-009417-458rrhcm	512	22	in	in	IN
cord-009417-458rrhcm	512	23	usual	usual	JJ
cord-009417-458rrhcm	512	24	transfusion	transfusion	NN
cord-009417-458rrhcm	512	25	practice	practice	NN
cord-009417-458rrhcm	512	26	:	:	:
cord-009417-458rrhcm	512	27	accumulation	accumulation	NN
cord-009417-458rrhcm	512	28	of	of	IN
cord-009417-458rrhcm	512	29	undesirable	undesirable	JJ
cord-009417-458rrhcm	512	30	substances	substance	NNS
cord-009417-458rrhcm	512	31	present	present	JJ
cord-009417-458rrhcm	512	32	within	within	IN
cord-009417-458rrhcm	512	33	banked	bank	VBN
cord-009417-458rrhcm	512	34	blood	blood	NN
cord-009417-458rrhcm	512	35	and	and	CC
cord-009417-458rrhcm	512	36	dilutional	dilutional	JJ
cord-009417-458rrhcm	512	37	depletion	depletion	NN
cord-009417-458rrhcm	512	38	of	of	IN
cord-009417-458rrhcm	512	39	normal	normal	JJ
cord-009417-458rrhcm	512	40	blood	blood	NN
cord-009417-458rrhcm	512	41	constituents	constituent	NNS
cord-009417-458rrhcm	512	42	that	that	WDT
cord-009417-458rrhcm	512	43	are	be	VBP
cord-009417-458rrhcm	512	44	lacking	lack	VBG
cord-009417-458rrhcm	512	45	in	in	IN
cord-009417-458rrhcm	512	46	stored	store	VBN
cord-009417-458rrhcm	512	47	units	unit	NNS
cord-009417-458rrhcm	512	48	.	.	.
cord-009417-458rrhcm	513	1	Trauma	trauma	NN
cord-009417-458rrhcm	513	2	victims	victim	NNS
cord-009417-458rrhcm	513	3	,	,	,
cord-009417-458rrhcm	513	4	surgical	surgical	JJ
cord-009417-458rrhcm	513	5	patients	patient	NNS
cord-009417-458rrhcm	513	6	undergoing	undergo	VBG
cord-009417-458rrhcm	513	7	extensive	extensive	JJ
cord-009417-458rrhcm	513	8	procedures	procedure	NNS
cord-009417-458rrhcm	513	9	,	,	,
cord-009417-458rrhcm	513	10	and	and	CC
cord-009417-458rrhcm	513	11	patients	patient	NNS
cord-009417-458rrhcm	513	12	with	with	IN
cord-009417-458rrhcm	513	13	vascular	vascular	JJ
cord-009417-458rrhcm	513	14	or	or	CC
cord-009417-458rrhcm	513	15	coagulation	coagulation	NN
cord-009417-458rrhcm	513	16	disorders	disorder	NNS
cord-009417-458rrhcm	513	17	may	may	MD
cord-009417-458rrhcm	513	18	be	be	VB
cord-009417-458rrhcm	513	19	massively	massively	RB
cord-009417-458rrhcm	513	20	transfused	transfuse	VBN
cord-009417-458rrhcm	513	21	in	in	IN
cord-009417-458rrhcm	513	22	the	the	DT
cord-009417-458rrhcm	513	23	critical	critical	JJ
cord-009417-458rrhcm	513	24	care	care	NN
cord-009417-458rrhcm	513	25	setting	setting	NN
cord-009417-458rrhcm	513	26	.	.	.
cord-009417-458rrhcm	514	1	Survival	survival	NN
cord-009417-458rrhcm	514	2	of	of	IN
cord-009417-458rrhcm	514	3	the	the	DT
cord-009417-458rrhcm	514	4	massive	massive	JJ
cord-009417-458rrhcm	514	5	transfusion	transfusion	NN
cord-009417-458rrhcm	514	6	episode	episode	NN
cord-009417-458rrhcm	514	7	is	be	VBZ
cord-009417-458rrhcm	514	8	determined	determine	VBN
cord-009417-458rrhcm	514	9	more	more	JJR
cord-009417-458rrhcm	514	10	by	by	IN
cord-009417-458rrhcm	514	11	the	the	DT
cord-009417-458rrhcm	514	12	nature	nature	NN
cord-009417-458rrhcm	514	13	and	and	CC
cord-009417-458rrhcm	514	14	degree	degree	NN
cord-009417-458rrhcm	514	15	of	of	IN
cord-009417-458rrhcm	514	16	the	the	DT
cord-009417-458rrhcm	514	17	patient	patient	NN
cord-009417-458rrhcm	514	18	's	's	POS
cord-009417-458rrhcm	514	19	injuries	injury	NNS
cord-009417-458rrhcm	514	20	or	or	CC
cord-009417-458rrhcm	514	21	medical	medical	JJ
cord-009417-458rrhcm	514	22	conditions	condition	NNS
cord-009417-458rrhcm	514	23	than	than	IN
cord-009417-458rrhcm	514	24	by	by	IN
cord-009417-458rrhcm	514	25	the	the	DT
cord-009417-458rrhcm	514	26	transfusions	transfusion	NNS
cord-009417-458rrhcm	514	27	themselves	-PRON-	PRP
cord-009417-458rrhcm	514	28	,	,	,
cord-009417-458rrhcm	514	29	but	but	CC
cord-009417-458rrhcm	514	30	the	the	DT
cord-009417-458rrhcm	514	31	presence	presence	NN
cord-009417-458rrhcm	514	32	of	of	IN
cord-009417-458rrhcm	514	33	adverse	adverse	JJ
cord-009417-458rrhcm	514	34	effects	effect	NNS
cord-009417-458rrhcm	514	35	of	of	IN
cord-009417-458rrhcm	514	36	massive	massive	JJ
cord-009417-458rrhcm	514	37	transfusion	transfusion	NN
cord-009417-458rrhcm	514	38	can	can	MD
cord-009417-458rrhcm	514	39	complicate	complicate	VB
cord-009417-458rrhcm	514	40	patients	patient	NNS
cord-009417-458rrhcm	514	41	'	'	POS
cord-009417-458rrhcm	514	42	courses	course	NNS
cord-009417-458rrhcm	514	43	in	in	IN
cord-009417-458rrhcm	514	44	the	the	DT
cord-009417-458rrhcm	514	45	ICU	ICU	NNP
cord-009417-458rrhcm	514	46	.	.	.
cord-009417-458rrhcm	515	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	515	2	of	of	IN
cord-009417-458rrhcm	515	3	large	large	JJ
cord-009417-458rrhcm	515	4	quantities	quantity	NNS
cord-009417-458rrhcm	515	5	of	of	IN
cord-009417-458rrhcm	515	6	stored	store	VBN
cord-009417-458rrhcm	515	7	blood	blood	NN
cord-009417-458rrhcm	515	8	defi	defi	NNP
cord-009417-458rrhcm	515	9	cient	cient	NN
cord-009417-458rrhcm	515	10	in	in	IN
cord-009417-458rrhcm	515	11	functional	functional	JJ
cord-009417-458rrhcm	515	12	platelets	platelet	NNS
cord-009417-458rrhcm	515	13	often	often	RB
cord-009417-458rrhcm	515	14	results	result	VBZ
cord-009417-458rrhcm	515	15	in	in	IN
cord-009417-458rrhcm	515	16	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	515	17	defects	defect	NNS
cord-009417-458rrhcm	515	18	or	or	CC
cord-009417-458rrhcm	515	19	outright	outright	JJ
cord-009417-458rrhcm	515	20	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	515	21	.	.	.
cord-009417-458rrhcm	516	1	Circulating	circulate	VBG
cord-009417-458rrhcm	516	2	platelets	platelet	NNS
cord-009417-458rrhcm	516	3	consistently	consistently	RB
cord-009417-458rrhcm	516	4	decrease	decrease	VBP
cord-009417-458rrhcm	516	5	in	in	IN
cord-009417-458rrhcm	516	6	inverse	inverse	JJ
cord-009417-458rrhcm	516	7	proportion	proportion	NN
cord-009417-458rrhcm	516	8	to	to	IN
cord-009417-458rrhcm	516	9	the	the	DT
cord-009417-458rrhcm	516	10	amount	amount	NN
cord-009417-458rrhcm	516	11	of	of	IN
cord-009417-458rrhcm	516	12	blood	blood	NN
cord-009417-458rrhcm	516	13	administered	administer	VBN
cord-009417-458rrhcm	516	14	,	,	,
cord-009417-458rrhcm	516	15	with	with	IN
cord-009417-458rrhcm	516	16	the	the	DT
cord-009417-458rrhcm	516	17	hemostatically	hemostatically	NNP
cord-009417-458rrhcm	516	18	signifi	signifi	NNP
cord-009417-458rrhcm	516	19	ca	can	MD
cord-009417-458rrhcm	516	20	nt	not	RB
cord-009417-458rrhcm	516	21	level	level	NN
cord-009417-458rrhcm	516	22	of	of	IN
cord-009417-458rrhcm	516	23	50	50	CD
cord-009417-458rrhcm	516	24	×	×	NN
cord-009417-458rrhcm	516	25	10	10	CD
cord-009417-458rrhcm	516	26	9	9	CD
cord-009417-458rrhcm	516	27	/L	/L	.
cord-009417-458rrhcm	516	28	reached	reach	VBN
cord-009417-458rrhcm	516	29	after	after	IN
cord-009417-458rrhcm	516	30	20	20	CD
cord-009417-458rrhcm	516	31	U.	U.	NNP
cord-009417-458rrhcm	516	32	112	112	CD
cord-009417-458rrhcm	516	33	,	,	,
cord-009417-458rrhcm	516	34	113	113	CD
cord-009417-458rrhcm	516	35	Functional	functional	JJ
cord-009417-458rrhcm	516	36	defects	defect	NNS
cord-009417-458rrhcm	516	37	have	have	VBP
cord-009417-458rrhcm	516	38	also	also	RB
cord-009417-458rrhcm	516	39	been	be	VBN
cord-009417-458rrhcm	516	40	noted	note	VBN
cord-009417-458rrhcm	516	41	,	,	,
cord-009417-458rrhcm	516	42	and	and	CC
cord-009417-458rrhcm	516	43	the	the	DT
cord-009417-458rrhcm	516	44	bleeding	bleeding	JJ
cord-009417-458rrhcm	516	45	time	time	NN
cord-009417-458rrhcm	516	46	is	be	VBZ
cord-009417-458rrhcm	516	47	prolonged	prolong	VBN
cord-009417-458rrhcm	516	48	.	.	.
cord-009417-458rrhcm	517	1	114	114	CD
cord-009417-458rrhcm	518	1	Despite	despite	IN
cord-009417-458rrhcm	518	2	these	these	DT
cord-009417-458rrhcm	518	3	laboratory	laboratory	NN
cord-009417-458rrhcm	518	4	changes	change	NNS
cord-009417-458rrhcm	518	5	,	,	,
cord-009417-458rrhcm	518	6	severe	severe	JJ
cord-009417-458rrhcm	518	7	diffuse	diffuse	NN
cord-009417-458rrhcm	518	8	bleeding	bleeding	NN
cord-009417-458rrhcm	518	9	develops	develop	VBZ
cord-009417-458rrhcm	518	10	in	in	IN
cord-009417-458rrhcm	518	11	less	less	JJR
cord-009417-458rrhcm	518	12	than	than	IN
cord-009417-458rrhcm	518	13	20	20	CD
cord-009417-458rrhcm	518	14	%	%	NN
cord-009417-458rrhcm	518	15	of	of	IN
cord-009417-458rrhcm	518	16	massively	massively	RB
cord-009417-458rrhcm	518	17	transfused	transfuse	VBN
cord-009417-458rrhcm	518	18	patients	patient	NNS
cord-009417-458rrhcm	518	19	,	,	,
cord-009417-458rrhcm	518	20	and	and	CC
cord-009417-458rrhcm	518	21	no	no	DT
cord-009417-458rrhcm	518	22	laboratory	laboratory	NN
cord-009417-458rrhcm	518	23	studies	study	NNS
cord-009417-458rrhcm	518	24	predict	predict	VBP
cord-009417-458rrhcm	518	25	those	those	DT
cord-009417-458rrhcm	518	26	who	who	WP
cord-009417-458rrhcm	518	27	will	will	MD
cord-009417-458rrhcm	518	28	.	.	.
cord-009417-458rrhcm	519	1	Prophylactic	prophylactic	JJ
cord-009417-458rrhcm	519	2	platelet	platelet	NN
cord-009417-458rrhcm	519	3	transfusion	transfusion	NN
cord-009417-458rrhcm	519	4	has	have	VBZ
cord-009417-458rrhcm	519	5	not	not	RB
cord-009417-458rrhcm	519	6	been	be	VBN
cord-009417-458rrhcm	519	7	shown	show	VBN
cord-009417-458rrhcm	519	8	to	to	TO
cord-009417-458rrhcm	519	9	be	be	VB
cord-009417-458rrhcm	519	10	of	of	IN
cord-009417-458rrhcm	519	11	benefi	benefi	NNP
cord-009417-458rrhcm	519	12	t.	t.	NNP
cord-009417-458rrhcm	519	13	115	115	CD
cord-009417-458rrhcm	519	14	Platelet	platelet	NN
cord-009417-458rrhcm	519	15	counts	count	NNS
cord-009417-458rrhcm	519	16	may	may	MD
cord-009417-458rrhcm	519	17	return	return	VB
cord-009417-458rrhcm	519	18	to	to	IN
cord-009417-458rrhcm	519	19	hemostatically	hemostatically	RB
cord-009417-458rrhcm	519	20	effective	effective	JJ
cord-009417-458rrhcm	519	21	levels	level	NNS
cord-009417-458rrhcm	519	22	quickly	quickly	RB
cord-009417-458rrhcm	519	23	in	in	IN
cord-009417-458rrhcm	519	24	patients	patient	NNS
cord-009417-458rrhcm	519	25	with	with	IN
cord-009417-458rrhcm	519	26	normal	normal	JJ
cord-009417-458rrhcm	519	27	marrow	marrow	NN
cord-009417-458rrhcm	519	28	function	function	NN
cord-009417-458rrhcm	519	29	.	.	.
cord-009417-458rrhcm	520	1	Currently	currently	RB
cord-009417-458rrhcm	520	2	,	,	,
cord-009417-458rrhcm	520	3	resuscitation	resuscitation	NN
cord-009417-458rrhcm	520	4	of	of	IN
cord-009417-458rrhcm	520	5	massively	massively	RB
cord-009417-458rrhcm	520	6	bleeding	bleed	VBG
cord-009417-458rrhcm	520	7	patients	patient	NNS
cord-009417-458rrhcm	520	8	is	be	VBZ
cord-009417-458rrhcm	520	9	most	most	RBS
cord-009417-458rrhcm	520	10	often	often	RB
cord-009417-458rrhcm	520	11	accomplished	accomplish	VBN
cord-009417-458rrhcm	520	12	with	with	IN
cord-009417-458rrhcm	520	13	PRBCs	prbc	NNS
cord-009417-458rrhcm	520	14	in	in	IN
cord-009417-458rrhcm	520	15	combination	combination	NN
cord-009417-458rrhcm	520	16	with	with	IN
cord-009417-458rrhcm	520	17	crystalloid	crystalloid	NN
cord-009417-458rrhcm	520	18	solution	solution	NN
cord-009417-458rrhcm	520	19	.	.	.
cord-009417-458rrhcm	521	1	This	this	DT
cord-009417-458rrhcm	521	2	should	should	MD
cord-009417-458rrhcm	521	3	result	result	VB
cord-009417-458rrhcm	521	4	in	in	IN
cord-009417-458rrhcm	521	5	hemodilution	hemodilution	NN
cord-009417-458rrhcm	521	6	to	to	IN
cord-009417-458rrhcm	521	7	about	about	RB
cord-009417-458rrhcm	521	8	60	60	CD
cord-009417-458rrhcm	521	9	%	%	NN
cord-009417-458rrhcm	521	10	of	of	IN
cord-009417-458rrhcm	521	11	normal	normal	JJ
cord-009417-458rrhcm	521	12	plasma	plasma	NN
cord-009417-458rrhcm	521	13	factor	factor	NN
cord-009417-458rrhcm	521	14	levels	level	NNS
cord-009417-458rrhcm	521	15	after	after	IN
cord-009417-458rrhcm	521	16	the	the	DT
cord-009417-458rrhcm	521	17	transfusion	transfusion	NN
cord-009417-458rrhcm	521	18	of	of	IN
cord-009417-458rrhcm	521	19	about	about	RB
cord-009417-458rrhcm	521	20	10	10	CD
cord-009417-458rrhcm	521	21	units	unit	NNS
cord-009417-458rrhcm	521	22	;	;	:
cord-009417-458rrhcm	521	23	this	this	DT
cord-009417-458rrhcm	521	24	factor	factor	NN
cord-009417-458rrhcm	521	25	level	level	NN
cord-009417-458rrhcm	521	26	can	can	MD
cord-009417-458rrhcm	521	27	effect	effect	VB
cord-009417-458rrhcm	521	28	normal	normal	JJ
cord-009417-458rrhcm	521	29	hemostasis	hemostasis	NN
cord-009417-458rrhcm	521	30	.	.	.
cord-009417-458rrhcm	522	1	In	in	IN
cord-009417-458rrhcm	522	2	reality	reality	NN
cord-009417-458rrhcm	522	3	,	,	,
cord-009417-458rrhcm	522	4	however	however	RB
cord-009417-458rrhcm	522	5	,	,	,
cord-009417-458rrhcm	522	6	crystalloids	crystalloids	NNP
cord-009417-458rrhcm	522	7	may	may	MD
cord-009417-458rrhcm	522	8	be	be	VB
cord-009417-458rrhcm	522	9	given	give	VBN
cord-009417-458rrhcm	522	10	in	in	IN
cord-009417-458rrhcm	522	11	excess	excess	NN
cord-009417-458rrhcm	522	12	of	of	IN
cord-009417-458rrhcm	522	13	PRBCs	prbc	NNS
cord-009417-458rrhcm	522	14	,	,	,
cord-009417-458rrhcm	522	15	so	so	RB
cord-009417-458rrhcm	522	16	after	after	IN
cord-009417-458rrhcm	522	17	10	10	CD
cord-009417-458rrhcm	522	18	units	unit	NNS
cord-009417-458rrhcm	522	19	is	be	VBZ
cord-009417-458rrhcm	522	20	transfused	transfuse	VBN
cord-009417-458rrhcm	522	21	,	,	,
cord-009417-458rrhcm	522	22	less	less	JJR
cord-009417-458rrhcm	522	23	plasma	plasma	NN
cord-009417-458rrhcm	522	24	protein	protein	NN
cord-009417-458rrhcm	522	25	may	may	MD
cord-009417-458rrhcm	522	26	remain	remain	VB
cord-009417-458rrhcm	522	27	.	.	.
cord-009417-458rrhcm	523	1	Bleeding	bleed	VBG
cord-009417-458rrhcm	523	2	is	be	VBZ
cord-009417-458rrhcm	523	3	unlikely	unlikely	JJ
cord-009417-458rrhcm	523	4	until	until	IN
cord-009417-458rrhcm	523	5	prothrombin	prothrombin	NN
cord-009417-458rrhcm	523	6	time	time	NN
cord-009417-458rrhcm	523	7	(	(	-LRB-
cord-009417-458rrhcm	523	8	PT)/INR	PT)/INR	NNP
cord-009417-458rrhcm	523	9	and	and	CC
cord-009417-458rrhcm	523	10	PTT	PTT	NNP
cord-009417-458rrhcm	523	11	prolongations	prolongation	NNS
cord-009417-458rrhcm	523	12	exceed	exceed	VBP
cord-009417-458rrhcm	523	13	1.5	1.5	CD
cord-009417-458rrhcm	523	14	to	to	TO
cord-009417-458rrhcm	523	15	1.8	1.8	CD
cord-009417-458rrhcm	523	16	times	time	NNS
cord-009417-458rrhcm	523	17	the	the	DT
cord-009417-458rrhcm	523	18	midpoint	midpoint	NN
cord-009417-458rrhcm	523	19	normal	normal	JJ
cord-009417-458rrhcm	523	20	range	range	NN
cord-009417-458rrhcm	523	21	,	,	,
cord-009417-458rrhcm	523	22	the	the	DT
cord-009417-458rrhcm	523	23	equivalent	equivalent	NN
cord-009417-458rrhcm	523	24	of	of	IN
cord-009417-458rrhcm	523	25	an	an	DT
cord-009417-458rrhcm	523	26	INR	INR	NNP
cord-009417-458rrhcm	523	27	approaching	approach	VBG
cord-009417-458rrhcm	523	28	2.0	2.0	CD
cord-009417-458rrhcm	523	29	.	.	.
cord-009417-458rrhcm	524	1	113	113	CD
cord-009417-458rrhcm	525	1	As	as	IN
cord-009417-458rrhcm	525	2	with	with	IN
cord-009417-458rrhcm	525	3	platelets	platelet	NNS
cord-009417-458rrhcm	525	4	,	,	,
cord-009417-458rrhcm	525	5	prophylactic	prophylactic	JJ
cord-009417-458rrhcm	525	6	administration	administration	NN
cord-009417-458rrhcm	525	7	of	of	IN
cord-009417-458rrhcm	525	8	FFP	FFP	NNP
cord-009417-458rrhcm	525	9	has	have	VBZ
cord-009417-458rrhcm	525	10	not	not	RB
cord-009417-458rrhcm	525	11	proved	prove	VBN
cord-009417-458rrhcm	525	12	effective	effective	JJ
cord-009417-458rrhcm	525	13	in	in	IN
cord-009417-458rrhcm	525	14	preventing	prevent	VBG
cord-009417-458rrhcm	525	15	diffuse	diffuse	JJ
cord-009417-458rrhcm	525	16	bleeding	bleeding	NN
cord-009417-458rrhcm	525	17	.	.	.
cord-009417-458rrhcm	526	1	116	116	CD
cord-009417-458rrhcm	527	1	Thus	thus	RB
cord-009417-458rrhcm	527	2	,	,	,
cord-009417-458rrhcm	527	3	the	the	DT
cord-009417-458rrhcm	527	4	decision	decision	NN
cord-009417-458rrhcm	527	5	to	to	TO
cord-009417-458rrhcm	527	6	transfuse	transfuse	VB
cord-009417-458rrhcm	527	7	should	should	MD
cord-009417-458rrhcm	527	8	be	be	VB
cord-009417-458rrhcm	527	9	made	make	VBN
cord-009417-458rrhcm	527	10	on	on	IN
cord-009417-458rrhcm	527	11	an	an	DT
cord-009417-458rrhcm	527	12	individual	individual	JJ
cord-009417-458rrhcm	527	13	basis	basis	NN
cord-009417-458rrhcm	527	14	,	,	,
cord-009417-458rrhcm	527	15	as	as	IN
cord-009417-458rrhcm	527	16	determined	determine	VBN
cord-009417-458rrhcm	527	17	by	by	IN
cord-009417-458rrhcm	527	18	the	the	DT
cord-009417-458rrhcm	527	19	presence	presence	NN
cord-009417-458rrhcm	527	20	of	of	IN
cord-009417-458rrhcm	527	21	bleeding	bleed	VBG
cord-009417-458rrhcm	527	22	or	or	CC
cord-009417-458rrhcm	527	23	unacceptable	unacceptable	JJ
cord-009417-458rrhcm	527	24	risk	risk	NN
cord-009417-458rrhcm	527	25	in	in	IN
cord-009417-458rrhcm	527	26	patients	patient	NNS
cord-009417-458rrhcm	527	27	with	with	IN
cord-009417-458rrhcm	527	28	documented	document	VBN
cord-009417-458rrhcm	527	29	abnormalities	abnormality	NNS
cord-009417-458rrhcm	527	30	in	in	IN
cord-009417-458rrhcm	527	31	coagulation	coagulation	NN
cord-009417-458rrhcm	527	32	.	.	.
cord-009417-458rrhcm	528	1	One	one	CD
cord-009417-458rrhcm	528	2	new	new	JJ
cord-009417-458rrhcm	528	3	area	area	NN
cord-009417-458rrhcm	528	4	of	of	IN
cord-009417-458rrhcm	528	5	controversy	controversy	NN
cord-009417-458rrhcm	528	6	in	in	IN
cord-009417-458rrhcm	528	7	the	the	DT
cord-009417-458rrhcm	528	8	treatment	treatment	NN
cord-009417-458rrhcm	528	9	of	of	IN
cord-009417-458rrhcm	528	10	patients	patient	NNS
cord-009417-458rrhcm	528	11	with	with	IN
cord-009417-458rrhcm	528	12	massive	massive	JJ
cord-009417-458rrhcm	528	13	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	528	14	is	be	VBZ
cord-009417-458rrhcm	528	15	the	the	DT
cord-009417-458rrhcm	528	16	use	use	NN
cord-009417-458rrhcm	528	17	of	of	IN
cord-009417-458rrhcm	528	18	recombinant	recombinant	JJ
cord-009417-458rrhcm	528	19	activated	activate	VBN
cord-009417-458rrhcm	528	20	factor	factor	NN
cord-009417-458rrhcm	528	21	VII	VII	NNP
cord-009417-458rrhcm	528	22	.	.	.
cord-009417-458rrhcm	529	1	This	this	DT
cord-009417-458rrhcm	529	2	new	new	JJ
cord-009417-458rrhcm	529	3	agent	agent	NN
cord-009417-458rrhcm	529	4	was	be	VBD
cord-009417-458rrhcm	529	5	created	create	VBN
cord-009417-458rrhcm	529	6	for	for	IN
cord-009417-458rrhcm	529	7	the	the	DT
cord-009417-458rrhcm	529	8	treatment	treatment	NN
cord-009417-458rrhcm	529	9	of	of	IN
cord-009417-458rrhcm	529	10	hemophiliac	hemophiliac	NN
cord-009417-458rrhcm	529	11	patients	patient	NNS
cord-009417-458rrhcm	529	12	with	with	IN
cord-009417-458rrhcm	529	13	high	high	JJ
cord-009417-458rrhcm	529	14	titers	titer	NNS
cord-009417-458rrhcm	529	15	of	of	IN
cord-009417-458rrhcm	529	16	antibodies	antibody	NNS
cord-009417-458rrhcm	529	17	to	to	TO
cord-009417-458rrhcm	529	18	factor	factor	VB
cord-009417-458rrhcm	529	19	VIII	VIII	NNP
cord-009417-458rrhcm	529	20	,	,	,
cord-009417-458rrhcm	529	21	which	which	WDT
cord-009417-458rrhcm	529	22	makes	make	VBZ
cord-009417-458rrhcm	529	23	them	-PRON-	PRP
cord-009417-458rrhcm	529	24	unable	unable	JJ
cord-009417-458rrhcm	529	25	to	to	TO
cord-009417-458rrhcm	529	26	benefi	benefi	NNP
cord-009417-458rrhcm	529	27	t	t	NN
cord-009417-458rrhcm	529	28	from	from	IN
cord-009417-458rrhcm	529	29	transfusion	transfusion	NN
cord-009417-458rrhcm	529	30	of	of	IN
cord-009417-458rrhcm	529	31	recombinant	recombinant	JJ
cord-009417-458rrhcm	529	32	factor	factor	NN
cord-009417-458rrhcm	529	33	VIII	VIII	NNP
cord-009417-458rrhcm	529	34	.	.	.
cord-009417-458rrhcm	530	1	Activated	activate	VBN
cord-009417-458rrhcm	530	2	factor	factor	NN
cord-009417-458rrhcm	530	3	VII	VII	NNP
cord-009417-458rrhcm	530	4	bypasses	bypass	VBZ
cord-009417-458rrhcm	530	5	that	that	DT
cord-009417-458rrhcm	530	6	problem	problem	NN
cord-009417-458rrhcm	530	7	by	by	IN
cord-009417-458rrhcm	530	8	binding	bind	VBG
cord-009417-458rrhcm	530	9	to	to	IN
cord-009417-458rrhcm	530	10	tissue	tissue	NN
cord-009417-458rrhcm	530	11	factor	factor	NN
cord-009417-458rrhcm	530	12	and	and	CC
cord-009417-458rrhcm	530	13	directly	directly	RB
cord-009417-458rrhcm	530	14	activating	activate	VBG
cord-009417-458rrhcm	530	15	thrombin	thrombin	NN
cord-009417-458rrhcm	530	16	and	and	CC
cord-009417-458rrhcm	530	17	hence	hence	RB
cord-009417-458rrhcm	530	18	generating	generate	VBG
cord-009417-458rrhcm	530	19	fi	fi	NNP
cord-009417-458rrhcm	530	20	brin	brin	NNP
cord-009417-458rrhcm	530	21	.	.	.
cord-009417-458rrhcm	531	1	117	117	CD
cord-009417-458rrhcm	532	1	It	-PRON-	PRP
cord-009417-458rrhcm	532	2	is	be	VBZ
cord-009417-458rrhcm	532	3	extremely	extremely	RB
cord-009417-458rrhcm	532	4	expensive	expensive	JJ
cord-009417-458rrhcm	532	5	,	,	,
cord-009417-458rrhcm	532	6	has	have	VBZ
cord-009417-458rrhcm	532	7	a	a	DT
cord-009417-458rrhcm	532	8	short	short	JJ
cord-009417-458rrhcm	532	9	half	half	JJ
cord-009417-458rrhcm	532	10	-	-	HYPH
cord-009417-458rrhcm	532	11	life	life	NN
cord-009417-458rrhcm	532	12	,	,	,
cord-009417-458rrhcm	532	13	and	and	CC
cord-009417-458rrhcm	532	14	carries	carry	VBZ
cord-009417-458rrhcm	532	15	a	a	DT
cord-009417-458rrhcm	532	16	risk	risk	NN
cord-009417-458rrhcm	532	17	of	of	IN
cord-009417-458rrhcm	532	18	inducing	induce	VBG
cord-009417-458rrhcm	532	19	pathologic	pathologic	JJ
cord-009417-458rrhcm	532	20	thrombosis	thrombosis	NN
cord-009417-458rrhcm	532	21	,	,	,
cord-009417-458rrhcm	532	22	with	with	IN
cord-009417-458rrhcm	532	23	potentially	potentially	RB
cord-009417-458rrhcm	532	24	grave	grave	JJ
cord-009417-458rrhcm	532	25	consequences	consequence	NNS
cord-009417-458rrhcm	532	26	.	.	.
cord-009417-458rrhcm	533	1	Nevertheless	nevertheless	RB
cord-009417-458rrhcm	533	2	,	,	,
cord-009417-458rrhcm	533	3	in	in	IN
cord-009417-458rrhcm	533	4	numerous	numerous	JJ
cord-009417-458rrhcm	533	5	case	case	NN
cord-009417-458rrhcm	533	6	reports	report	NNS
cord-009417-458rrhcm	533	7	,	,	,
cord-009417-458rrhcm	533	8	this	this	DT
cord-009417-458rrhcm	533	9	new	new	JJ
cord-009417-458rrhcm	533	10	agent	agent	NN
cord-009417-458rrhcm	533	11	appears	appear	VBZ
cord-009417-458rrhcm	533	12	to	to	TO
cord-009417-458rrhcm	533	13	potentially	potentially	RB
cord-009417-458rrhcm	533	14	be	be	VB
cord-009417-458rrhcm	533	15	benefi	benefi	NNP
cord-009417-458rrhcm	533	16	cial	cial	NN
cord-009417-458rrhcm	533	17	if	if	IN
cord-009417-458rrhcm	533	18	used	use	VBN
cord-009417-458rrhcm	533	19	early	early	RB
cord-009417-458rrhcm	533	20	in	in	IN
cord-009417-458rrhcm	533	21	the	the	DT
cord-009417-458rrhcm	533	22	resuscitation	resuscitation	NN
cord-009417-458rrhcm	533	23	of	of	IN
cord-009417-458rrhcm	533	24	massively	massively	RB
cord-009417-458rrhcm	533	25	injured	injure	VBN
cord-009417-458rrhcm	533	26	patients	patient	NNS
cord-009417-458rrhcm	533	27	.	.	.
cord-009417-458rrhcm	534	1	Unfortunately	unfortunately	RB
cord-009417-458rrhcm	534	2	,	,	,
cord-009417-458rrhcm	534	3	its	-PRON-	PRP$
cord-009417-458rrhcm	534	4	unsupervised	unsupervised	JJ
cord-009417-458rrhcm	534	5	use	use	NN
cord-009417-458rrhcm	534	6	has	have	VBZ
cord-009417-458rrhcm	534	7	also	also	RB
cord-009417-458rrhcm	534	8	resulted	result	VBN
cord-009417-458rrhcm	534	9	in	in	IN
cord-009417-458rrhcm	534	10	thrombotic	thrombotic	JJ
cord-009417-458rrhcm	534	11	complications	complication	NNS
cord-009417-458rrhcm	534	12	and	and	CC
cord-009417-458rrhcm	534	13	relative	relative	JJ
cord-009417-458rrhcm	534	14	lack	lack	NN
cord-009417-458rrhcm	534	15	of	of	IN
cord-009417-458rrhcm	534	16	success	success	NN
cord-009417-458rrhcm	534	17	,	,	,
cord-009417-458rrhcm	534	18	both	both	DT
cord-009417-458rrhcm	534	19	of	of	IN
cord-009417-458rrhcm	534	20	which	which	WDT
cord-009417-458rrhcm	534	21	suggest	suggest	VBP
cord-009417-458rrhcm	534	22	that	that	IN
cord-009417-458rrhcm	534	23	carefully	carefully	RB
cord-009417-458rrhcm	534	24	controlled	control	VBN
cord-009417-458rrhcm	534	25	clinical	clinical	JJ
cord-009417-458rrhcm	534	26	trials	trial	NNS
cord-009417-458rrhcm	534	27	are	be	VBP
cord-009417-458rrhcm	534	28	appropriate	appropriate	JJ
cord-009417-458rrhcm	534	29	.	.	.
cord-009417-458rrhcm	535	1	118	118	CD
cord-009417-458rrhcm	535	2	Blood	blood	NN
cord-009417-458rrhcm	535	3	preservative	preservative	NN
cord-009417-458rrhcm	535	4	solutions	solution	NNS
cord-009417-458rrhcm	535	5	contain	contain	VBP
cord-009417-458rrhcm	535	6	excess	excess	JJ
cord-009417-458rrhcm	535	7	citrate	citrate	NN
cord-009417-458rrhcm	535	8	,	,	,
cord-009417-458rrhcm	535	9	which	which	WDT
cord-009417-458rrhcm	535	10	anticoagulates	anticoagulate	VBZ
cord-009417-458rrhcm	535	11	stored	store	VBD
cord-009417-458rrhcm	535	12	blood	blood	NN
cord-009417-458rrhcm	535	13	by	by	IN
cord-009417-458rrhcm	535	14	binding	bind	VBG
cord-009417-458rrhcm	535	15	ionized	ionized	JJ
cord-009417-458rrhcm	535	16	calcium	calcium	NN
cord-009417-458rrhcm	535	17	.	.	.
cord-009417-458rrhcm	536	1	WB	WB	NNP
cord-009417-458rrhcm	536	2	contains	contain	VBZ
cord-009417-458rrhcm	536	3	approximately	approximately	RB
cord-009417-458rrhcm	536	4	1.8	1.8	CD
cord-009417-458rrhcm	536	5	g	g	NN
cord-009417-458rrhcm	536	6	of	of	IN
cord-009417-458rrhcm	536	7	citrate	citrate	NN
cord-009417-458rrhcm	536	8	/	/	SYM
cord-009417-458rrhcm	536	9	citric	citric	NN
cord-009417-458rrhcm	536	10	acid	acid	NN
cord-009417-458rrhcm	536	11	per	per	IN
cord-009417-458rrhcm	536	12	unit	unit	NN
cord-009417-458rrhcm	536	13	in	in	IN
cord-009417-458rrhcm	536	14	the	the	DT
cord-009417-458rrhcm	536	15	plasma	plasma	NN
cord-009417-458rrhcm	536	16	fraction	fraction	NN
cord-009417-458rrhcm	536	17	.	.	.
cord-009417-458rrhcm	537	1	Patients	patient	NNS
cord-009417-458rrhcm	537	2	with	with	IN
cord-009417-458rrhcm	537	3	normal	normal	JJ
cord-009417-458rrhcm	537	4	liver	liver	NN
cord-009417-458rrhcm	537	5	function	function	NN
cord-009417-458rrhcm	537	6	can	can	MD
cord-009417-458rrhcm	537	7	metabolize	metabolize	VB
cord-009417-458rrhcm	537	8	the	the	DT
cord-009417-458rrhcm	537	9	citrate	citrate	NN
cord-009417-458rrhcm	537	10	load	load	NN
cord-009417-458rrhcm	537	11	in	in	IN
cord-009417-458rrhcm	537	12	1	1	CD
cord-009417-458rrhcm	537	13	unit	unit	NN
cord-009417-458rrhcm	537	14	of	of	IN
cord-009417-458rrhcm	537	15	WB	WB	NNP
cord-009417-458rrhcm	537	16	in	in	IN
cord-009417-458rrhcm	537	17	5	5	CD
cord-009417-458rrhcm	537	18	minutes	minute	NNS
cord-009417-458rrhcm	537	19	,	,	,
cord-009417-458rrhcm	537	20	but	but	CC
cord-009417-458rrhcm	537	21	hepatic	hepatic	JJ
cord-009417-458rrhcm	537	22	impairment	impairment	NN
cord-009417-458rrhcm	537	23	may	may	MD
cord-009417-458rrhcm	537	24	extend	extend	VB
cord-009417-458rrhcm	537	25	removal	removal	NN
cord-009417-458rrhcm	537	26	to	to	IN
cord-009417-458rrhcm	537	27	15	15	CD
cord-009417-458rrhcm	537	28	minutes	minute	NNS
cord-009417-458rrhcm	537	29	or	or	CC
cord-009417-458rrhcm	537	30	longer	long	JJR
cord-009417-458rrhcm	537	31	.	.	.
cord-009417-458rrhcm	538	1	Toxicity	toxicity	NN
cord-009417-458rrhcm	538	2	may	may	MD
cord-009417-458rrhcm	538	3	result	result	VB
cord-009417-458rrhcm	538	4	when	when	WRB
cord-009417-458rrhcm	538	5	citrate	citrate	NN
cord-009417-458rrhcm	538	6	is	be	VBZ
cord-009417-458rrhcm	538	7	administered	administer	VBN
cord-009417-458rrhcm	538	8	in	in	IN
cord-009417-458rrhcm	538	9	excess	excess	NN
cord-009417-458rrhcm	538	10	of	of	IN
cord-009417-458rrhcm	538	11	the	the	DT
cord-009417-458rrhcm	538	12	metabolic	metabolic	JJ
cord-009417-458rrhcm	538	13	rate	rate	NN
cord-009417-458rrhcm	538	14	,	,	,
cord-009417-458rrhcm	538	15	thereby	thereby	RB
cord-009417-458rrhcm	538	16	causing	cause	VBG
cord-009417-458rrhcm	538	17	a	a	DT
cord-009417-458rrhcm	538	18	decrease	decrease	NN
cord-009417-458rrhcm	538	19	in	in	IN
cord-009417-458rrhcm	538	20	ionized	ionized	JJ
cord-009417-458rrhcm	538	21	calcium	calcium	NN
cord-009417-458rrhcm	538	22	levels	level	NNS
cord-009417-458rrhcm	538	23	.	.	.
cord-009417-458rrhcm	539	1	119	119	CD
cord-009417-458rrhcm	540	1	Although	although	IN
cord-009417-458rrhcm	540	2	paresthesias	paresthesias	NNP
cord-009417-458rrhcm	540	3	,	,	,
cord-009417-458rrhcm	540	4	cramps	cramp	NNS
cord-009417-458rrhcm	540	5	,	,	,
cord-009417-458rrhcm	540	6	and	and	CC
cord-009417-458rrhcm	540	7	myoclonus	myoclonus	NN
cord-009417-458rrhcm	540	8	accompany	accompany	VBP
cord-009417-458rrhcm	540	9	citrate	citrate	NN
cord-009417-458rrhcm	540	10	excess	excess	NN
cord-009417-458rrhcm	540	11	,	,	,
cord-009417-458rrhcm	540	12	the	the	DT
cord-009417-458rrhcm	540	13	chief	chief	JJ
cord-009417-458rrhcm	540	14	danger	danger	NN
cord-009417-458rrhcm	540	15	of	of	IN
cord-009417-458rrhcm	540	16	hypocalcemia	hypocalcemia	NN
cord-009417-458rrhcm	540	17	is	be	VBZ
cord-009417-458rrhcm	540	18	depression	depression	NN
cord-009417-458rrhcm	540	19	of	of	IN
cord-009417-458rrhcm	540	20	myocardial	myocardial	JJ
cord-009417-458rrhcm	540	21	contractility	contractility	NN
cord-009417-458rrhcm	540	22	and	and	CC
cord-009417-458rrhcm	540	23	potential	potential	JJ
cord-009417-458rrhcm	540	24	prolongation	prolongation	NN
cord-009417-458rrhcm	540	25	of	of	IN
cord-009417-458rrhcm	540	26	the	the	DT
cord-009417-458rrhcm	540	27	QT	QT	NNP
cord-009417-458rrhcm	540	28	interval	interval	NN
cord-009417-458rrhcm	540	29	.	.	.
cord-009417-458rrhcm	541	1	Because	because	IN
cord-009417-458rrhcm	541	2	the	the	DT
cord-009417-458rrhcm	541	3	effects	effect	NNS
cord-009417-458rrhcm	541	4	of	of	IN
cord-009417-458rrhcm	541	5	citrate	citrate	NN
cord-009417-458rrhcm	541	6	are	be	VBP
cord-009417-458rrhcm	541	7	transient	transient	JJ
cord-009417-458rrhcm	541	8	and	and	CC
cord-009417-458rrhcm	541	9	the	the	DT
cord-009417-458rrhcm	541	10	use	use	NN
cord-009417-458rrhcm	541	11	of	of	IN
cord-009417-458rrhcm	541	12	PRBCs	prbc	NNS
cord-009417-458rrhcm	541	13	containing	contain	VBG
cord-009417-458rrhcm	541	14	little	little	JJ
cord-009417-458rrhcm	541	15	residual	residual	JJ
cord-009417-458rrhcm	541	16	citrated	citrate	VBN
cord-009417-458rrhcm	541	17	plasma	plasma	NN
cord-009417-458rrhcm	541	18	is	be	VBZ
cord-009417-458rrhcm	541	19	far	far	RB
cord-009417-458rrhcm	541	20	more	more	RBR
cord-009417-458rrhcm	541	21	common	common	JJ
cord-009417-458rrhcm	541	22	than	than	IN
cord-009417-458rrhcm	541	23	massive	massive	JJ
cord-009417-458rrhcm	541	24	transfusion	transfusion	NN
cord-009417-458rrhcm	541	25	with	with	IN
cord-009417-458rrhcm	541	26	WB	WB	NNP
cord-009417-458rrhcm	541	27	,	,	,
cord-009417-458rrhcm	541	28	routine	routine	JJ
cord-009417-458rrhcm	541	29	administration	administration	NN
cord-009417-458rrhcm	541	30	of	of	IN
cord-009417-458rrhcm	541	31	calcium	calcium	NN
cord-009417-458rrhcm	541	32	is	be	VBZ
cord-009417-458rrhcm	541	33	not	not	RB
cord-009417-458rrhcm	541	34	indicated	indicate	VBN
cord-009417-458rrhcm	541	35	;	;	:
cord-009417-458rrhcm	541	36	clinically	clinically	RB
cord-009417-458rrhcm	541	37	signifi	signifi	NNP
cord-009417-458rrhcm	541	38	ca	can	MD
cord-009417-458rrhcm	541	39	nt	not	RB
cord-009417-458rrhcm	541	40	rebound	rebound	VB
cord-009417-458rrhcm	541	41	hypercalcemia	hypercalcemia	NN
cord-009417-458rrhcm	541	42	may	may	MD
cord-009417-458rrhcm	541	43	result	result	VB
cord-009417-458rrhcm	541	44	.	.	.
cord-009417-458rrhcm	542	1	Calcium	calcium	NN
cord-009417-458rrhcm	542	2	infusion	infusion	NN
cord-009417-458rrhcm	542	3	should	should	MD
cord-009417-458rrhcm	542	4	be	be	VB
cord-009417-458rrhcm	542	5	limited	limit	VBN
cord-009417-458rrhcm	542	6	to	to	IN
cord-009417-458rrhcm	542	7	hypoperfused	hypoperfuse	VBN
cord-009417-458rrhcm	542	8	patients	patient	NNS
cord-009417-458rrhcm	542	9	with	with	IN
cord-009417-458rrhcm	542	10	hepatic	hepatic	JJ
cord-009417-458rrhcm	542	11	or	or	CC
cord-009417-458rrhcm	542	12	cardiac	cardiac	JJ
cord-009417-458rrhcm	542	13	failure	failure	NN
cord-009417-458rrhcm	542	14	who	who	WP
cord-009417-458rrhcm	542	15	manifest	manifest	VBP
cord-009417-458rrhcm	542	16	citrate	citrate	NN
cord-009417-458rrhcm	542	17	toxicity	toxicity	NN
cord-009417-458rrhcm	542	18	,	,	,
cord-009417-458rrhcm	542	19	and	and	CC
cord-009417-458rrhcm	542	20	careful	careful	JJ
cord-009417-458rrhcm	542	21	monitoring	monitoring	NN
cord-009417-458rrhcm	542	22	is	be	VBZ
cord-009417-458rrhcm	542	23	essential	essential	JJ
cord-009417-458rrhcm	542	24	.	.	.
cord-009417-458rrhcm	543	1	As	as	IN
cord-009417-458rrhcm	543	2	potassium	potassium	NN
cord-009417-458rrhcm	543	3	leaks	leak	NNS
cord-009417-458rrhcm	543	4	from	from	IN
cord-009417-458rrhcm	543	5	RBCs	rbc	NNS
cord-009417-458rrhcm	543	6	during	during	IN
cord-009417-458rrhcm	543	7	storage	storage	NN
cord-009417-458rrhcm	543	8	,	,	,
cord-009417-458rrhcm	543	9	up	up	IN
cord-009417-458rrhcm	543	10	to	to	TO
cord-009417-458rrhcm	543	11	7	7	CD
cord-009417-458rrhcm	543	12	mEq	mEq	NNS
cord-009417-458rrhcm	543	13	of	of	IN
cord-009417-458rrhcm	543	14	extracellular	extracellular	JJ
cord-009417-458rrhcm	543	15	potassium	potassium	NN
cord-009417-458rrhcm	543	16	may	may	MD
cord-009417-458rrhcm	543	17	accumulate	accumulate	VB
cord-009417-458rrhcm	543	18	in	in	IN
cord-009417-458rrhcm	543	19	each	each	DT
cord-009417-458rrhcm	543	20	unit	unit	NN
cord-009417-458rrhcm	543	21	.	.	.
cord-009417-458rrhcm	544	1	However	however	RB
cord-009417-458rrhcm	544	2	,	,	,
cord-009417-458rrhcm	544	3	dangerous	dangerous	JJ
cord-009417-458rrhcm	544	4	levels	level	NNS
cord-009417-458rrhcm	544	5	of	of	IN
cord-009417-458rrhcm	544	6	potassium	potassium	NN
cord-009417-458rrhcm	544	7	rarely	rarely	RB
cord-009417-458rrhcm	544	8	develop	develop	VBP
cord-009417-458rrhcm	544	9	in	in	IN
cord-009417-458rrhcm	544	10	adults	adult	NNS
cord-009417-458rrhcm	544	11	from	from	IN
cord-009417-458rrhcm	544	12	stored	store	VBN
cord-009417-458rrhcm	544	13	blood	blood	NN
cord-009417-458rrhcm	544	14	;	;	:
cord-009417-458rrhcm	544	15	the	the	DT
cord-009417-458rrhcm	544	16	potassium	potassium	NN
cord-009417-458rrhcm	544	17	level	level	NN
cord-009417-458rrhcm	544	18	is	be	VBZ
cord-009417-458rrhcm	544	19	more	more	RBR
cord-009417-458rrhcm	544	20	likely	likely	JJ
cord-009417-458rrhcm	544	21	to	to	TO
cord-009417-458rrhcm	544	22	be	be	VB
cord-009417-458rrhcm	544	23	determined	determine	VBN
cord-009417-458rrhcm	544	24	by	by	IN
cord-009417-458rrhcm	544	25	the	the	DT
cord-009417-458rrhcm	544	26	patient	patient	NN
cord-009417-458rrhcm	544	27	's	's	POS
cord-009417-458rrhcm	544	28	acid	acid	NN
cord-009417-458rrhcm	544	29	-	-	HYPH
cord-009417-458rrhcm	544	30	base	base	NN
cord-009417-458rrhcm	544	31	status	status	NN
cord-009417-458rrhcm	544	32	.	.	.
cord-009417-458rrhcm	545	1	117	117	CD
cord-009417-458rrhcm	545	2	Studies	study	NNS
cord-009417-458rrhcm	545	3	of	of	IN
cord-009417-458rrhcm	545	4	massively	massively	RB
cord-009417-458rrhcm	545	5	transfused	transfuse	VBN
cord-009417-458rrhcm	545	6	patients	patient	NNS
cord-009417-458rrhcm	545	7	have	have	VBP
cord-009417-458rrhcm	545	8	demonstrated	demonstrate	VBN
cord-009417-458rrhcm	545	9	a	a	DT
cord-009417-458rrhcm	545	10	wide	wide	JJ
cord-009417-458rrhcm	545	11	range	range	NN
cord-009417-458rrhcm	545	12	of	of	IN
cord-009417-458rrhcm	545	13	potassium	potassium	NN
cord-009417-458rrhcm	545	14	levels	level	NNS
cord-009417-458rrhcm	545	15	,	,	,
cord-009417-458rrhcm	545	16	with	with	IN
cord-009417-458rrhcm	545	17	hypokalemia	hypokalemia	NN
cord-009417-458rrhcm	545	18	seen	see	VBN
cord-009417-458rrhcm	545	19	as	as	RB
cord-009417-458rrhcm	545	20	frequently	frequently	RB
cord-009417-458rrhcm	545	21	as	as	IN
cord-009417-458rrhcm	545	22	hyperkalemia	hyperkalemia	NN
cord-009417-458rrhcm	545	23	.	.	.
cord-009417-458rrhcm	546	1	Because	because	IN
cord-009417-458rrhcm	546	2	of	of	IN
cord-009417-458rrhcm	546	3	the	the	DT
cord-009417-458rrhcm	546	4	many	many	JJ
cord-009417-458rrhcm	546	5	physiologic	physiologic	JJ
cord-009417-458rrhcm	546	6	mechanisms	mechanism	NNS
cord-009417-458rrhcm	546	7	altered	alter	VBN
cord-009417-458rrhcm	546	8	during	during	IN
cord-009417-458rrhcm	546	9	resuscitation	resuscitation	NN
cord-009417-458rrhcm	546	10	,	,	,
cord-009417-458rrhcm	546	11	including	include	VBG
cord-009417-458rrhcm	546	12	those	those	DT
cord-009417-458rrhcm	546	13	of	of	IN
cord-009417-458rrhcm	546	14	the	the	DT
cord-009417-458rrhcm	546	15	respiratory	respiratory	JJ
cord-009417-458rrhcm	546	16	,	,	,
cord-009417-458rrhcm	546	17	renal	renal	JJ
cord-009417-458rrhcm	546	18	,	,	,
cord-009417-458rrhcm	546	19	cardiac	cardiac	NN
cord-009417-458rrhcm	546	20	,	,	,
cord-009417-458rrhcm	546	21	and	and	CC
cord-009417-458rrhcm	546	22	hepatic	hepatic	JJ
cord-009417-458rrhcm	546	23	systems	system	NNS
cord-009417-458rrhcm	546	24	,	,	,
cord-009417-458rrhcm	546	25	it	-PRON-	PRP
cord-009417-458rrhcm	546	26	is	be	VBZ
cord-009417-458rrhcm	546	27	impossible	impossible	JJ
cord-009417-458rrhcm	546	28	to	to	TO
cord-009417-458rrhcm	546	29	predict	predict	VB
cord-009417-458rrhcm	546	30	the	the	DT
cord-009417-458rrhcm	546	31	net	net	JJ
cord-009417-458rrhcm	546	32	effect	effect	NN
cord-009417-458rrhcm	546	33	of	of	IN
cord-009417-458rrhcm	546	34	massive	massive	JJ
cord-009417-458rrhcm	546	35	transfusion	transfusion	NN
cord-009417-458rrhcm	546	36	on	on	IN
cord-009417-458rrhcm	546	37	serum	serum	NN
cord-009417-458rrhcm	546	38	potassium	potassium	NN
cord-009417-458rrhcm	546	39	levels	level	NNS
cord-009417-458rrhcm	546	40	.	.	.
cord-009417-458rrhcm	547	1	The	the	DT
cord-009417-458rrhcm	547	2	pH	ph	NN
cord-009417-458rrhcm	547	3	of	of	IN
cord-009417-458rrhcm	547	4	banked	banked	JJ
cord-009417-458rrhcm	547	5	blood	blood	NN
cord-009417-458rrhcm	547	6	drops	drop	NNS
cord-009417-458rrhcm	547	7	during	during	IN
cord-009417-458rrhcm	547	8	storage	storage	NN
cord-009417-458rrhcm	547	9	,	,	,
cord-009417-458rrhcm	547	10	from	from	IN
cord-009417-458rrhcm	547	11	7.16	7.16	CD
cord-009417-458rrhcm	547	12	at	at	IN
cord-009417-458rrhcm	547	13	the	the	DT
cord-009417-458rrhcm	547	14	time	time	NN
cord-009417-458rrhcm	547	15	of	of	IN
cord-009417-458rrhcm	547	16	collection	collection	NN
cord-009417-458rrhcm	547	17	to	to	IN
cord-009417-458rrhcm	547	18	as	as	RB
cord-009417-458rrhcm	547	19	low	low	JJ
cord-009417-458rrhcm	547	20	as	as	IN
cord-009417-458rrhcm	547	21	6.73	6.73	CD
cord-009417-458rrhcm	547	22	after	after	IN
cord-009417-458rrhcm	547	23	several	several	JJ
cord-009417-458rrhcm	547	24	weeks	week	NNS
cord-009417-458rrhcm	547	25	of	of	IN
cord-009417-458rrhcm	547	26	storage	storage	NN
cord-009417-458rrhcm	547	27	.	.	.
cord-009417-458rrhcm	548	1	Administration	administration	NN
cord-009417-458rrhcm	548	2	of	of	IN
cord-009417-458rrhcm	548	3	large	large	JJ
cord-009417-458rrhcm	548	4	quantities	quantity	NNS
cord-009417-458rrhcm	548	5	of	of	IN
cord-009417-458rrhcm	548	6	acidic	acidic	JJ
cord-009417-458rrhcm	548	7	blood	blood	NN
cord-009417-458rrhcm	548	8	,	,	,
cord-009417-458rrhcm	548	9	together	together	RB
cord-009417-458rrhcm	548	10	with	with	IN
cord-009417-458rrhcm	548	11	the	the	DT
cord-009417-458rrhcm	548	12	metabolic	metabolic	JJ
cord-009417-458rrhcm	548	13	acidosis	acidosis	NN
cord-009417-458rrhcm	548	14	common	common	JJ
cord-009417-458rrhcm	548	15	in	in	IN
cord-009417-458rrhcm	548	16	these	these	DT
cord-009417-458rrhcm	548	17	patients	patient	NNS
cord-009417-458rrhcm	548	18	before	before	IN
cord-009417-458rrhcm	548	19	resuscitation	resuscitation	NN
cord-009417-458rrhcm	548	20	,	,	,
cord-009417-458rrhcm	548	21	would	would	MD
cord-009417-458rrhcm	548	22	lead	lead	VB
cord-009417-458rrhcm	548	23	one	one	PRP
cord-009417-458rrhcm	548	24	to	to	TO
cord-009417-458rrhcm	548	25	expect	expect	VB
cord-009417-458rrhcm	548	26	worsening	worsen	VBG
cord-009417-458rrhcm	548	27	acidosis	acidosis	NN
cord-009417-458rrhcm	548	28	as	as	IN
cord-009417-458rrhcm	548	29	the	the	DT
cord-009417-458rrhcm	548	30	outcome	outcome	NN
cord-009417-458rrhcm	548	31	of	of	IN
cord-009417-458rrhcm	548	32	massive	massive	JJ
cord-009417-458rrhcm	548	33	transfusion	transfusion	NN
cord-009417-458rrhcm	548	34	.	.	.
cord-009417-458rrhcm	549	1	However	however	RB
cord-009417-458rrhcm	549	2	,	,	,
cord-009417-458rrhcm	549	3	patients	patient	NNS
cord-009417-458rrhcm	549	4	are	be	VBP
cord-009417-458rrhcm	549	5	more	more	RBR
cord-009417-458rrhcm	549	6	likely	likely	JJ
cord-009417-458rrhcm	549	7	to	to	TO
cord-009417-458rrhcm	549	8	exhibit	exhibit	VB
cord-009417-458rrhcm	549	9	metabolic	metabolic	JJ
cord-009417-458rrhcm	549	10	alkalosis	alkalosis	NN
cord-009417-458rrhcm	549	11	at	at	IN
cord-009417-458rrhcm	549	12	the	the	DT
cord-009417-458rrhcm	549	13	end	end	NN
cord-009417-458rrhcm	549	14	of	of	IN
cord-009417-458rrhcm	549	15	the	the	DT
cord-009417-458rrhcm	549	16	transfusion	transfusion	NN
cord-009417-458rrhcm	549	17	episode	episode	NN
cord-009417-458rrhcm	549	18	,	,	,
cord-009417-458rrhcm	549	19	120,121	120,121	CD
cord-009417-458rrhcm	549	20	partly	partly	RB
cord-009417-458rrhcm	549	21	because	because	IN
cord-009417-458rrhcm	549	22	of	of	IN
cord-009417-458rrhcm	549	23	improved	improve	VBN
cord-009417-458rrhcm	549	24	tissue	tissue	NN
cord-009417-458rrhcm	549	25	perfusion	perfusion	NN
cord-009417-458rrhcm	549	26	and	and	CC
cord-009417-458rrhcm	549	27	the	the	DT
cord-009417-458rrhcm	549	28	metabolism	metabolism	NN
cord-009417-458rrhcm	549	29	of	of	IN
cord-009417-458rrhcm	549	30	citrate	citrate	NN
cord-009417-458rrhcm	549	31	and	and	CC
cord-009417-458rrhcm	549	32	lactate	lactate	NN
cord-009417-458rrhcm	549	33	to	to	IN
cord-009417-458rrhcm	549	34	bicarbonate	bicarbonate	NN
cord-009417-458rrhcm	549	35	.	.	.
cord-009417-458rrhcm	550	1	Patients	patient	NNS
cord-009417-458rrhcm	550	2	in	in	IN
cord-009417-458rrhcm	550	3	renal	renal	JJ
cord-009417-458rrhcm	550	4	failure	failure	NN
cord-009417-458rrhcm	550	5	may	may	MD
cord-009417-458rrhcm	550	6	be	be	VB
cord-009417-458rrhcm	550	7	unable	unable	JJ
cord-009417-458rrhcm	550	8	to	to	TO
cord-009417-458rrhcm	550	9	handle	handle	VB
cord-009417-458rrhcm	550	10	the	the	DT
cord-009417-458rrhcm	550	11	bicarbonate	bicarbonate	NN
cord-009417-458rrhcm	550	12	load	load	NN
cord-009417-458rrhcm	550	13	and	and	CC
cord-009417-458rrhcm	550	14	require	require	VBP
cord-009417-458rrhcm	550	15	dialysis	dialysis	NN
cord-009417-458rrhcm	550	16	.	.	.
cord-009417-458rrhcm	551	1	Acidosis	acidosis	NN
cord-009417-458rrhcm	551	2	persisting	persist	VBG
cord-009417-458rrhcm	551	3	after	after	IN
cord-009417-458rrhcm	551	4	transfusion	transfusion	NN
cord-009417-458rrhcm	551	5	suggests	suggest	VBZ
cord-009417-458rrhcm	551	6	inadequate	inadequate	JJ
cord-009417-458rrhcm	551	7	tissue	tissue	NN
cord-009417-458rrhcm	551	8	perfusion	perfusion	NN
cord-009417-458rrhcm	551	9	.	.	.
cord-009417-458rrhcm	552	1	119	119	CD
cord-009417-458rrhcm	552	2	Empiric	Empiric	NNP
cord-009417-458rrhcm	552	3	administration	administration	NN
cord-009417-458rrhcm	552	4	of	of	IN
cord-009417-458rrhcm	552	5	bicarbonate	bicarbonate	NNP
cord-009417-458rrhcm	552	6	to	to	TO
cord-009417-458rrhcm	552	7	counter	counter	VB
cord-009417-458rrhcm	552	8	the	the	DT
cord-009417-458rrhcm	552	9	acid	acid	NN
cord-009417-458rrhcm	552	10	load	load	NN
cord-009417-458rrhcm	552	11	is	be	VBZ
cord-009417-458rrhcm	552	12	not	not	RB
cord-009417-458rrhcm	552	13	warranted	warrant	VBN
cord-009417-458rrhcm	552	14	and	and	CC
cord-009417-458rrhcm	552	15	may	may	MD
cord-009417-458rrhcm	552	16	contribute	contribute	VB
cord-009417-458rrhcm	552	17	to	to	IN
cord-009417-458rrhcm	552	18	the	the	DT
cord-009417-458rrhcm	552	19	deleterious	deleterious	JJ
cord-009417-458rrhcm	552	20	effects	effect	NNS
cord-009417-458rrhcm	552	21	of	of	IN
cord-009417-458rrhcm	552	22	hypercapnia	hypercapnia	NN
cord-009417-458rrhcm	552	23	in	in	IN
cord-009417-458rrhcm	552	24	patients	patient	NNS
cord-009417-458rrhcm	552	25	with	with	IN
cord-009417-458rrhcm	552	26	impaired	impaired	JJ
cord-009417-458rrhcm	552	27	ventilation	ventilation	NN
cord-009417-458rrhcm	552	28	.	.	.
cord-009417-458rrhcm	553	1	As	as	IN
cord-009417-458rrhcm	553	2	discussed	discuss	VBN
cord-009417-458rrhcm	553	3	previously	previously	RB
cord-009417-458rrhcm	553	4	,	,	,
cord-009417-458rrhcm	553	5	the	the	DT
cord-009417-458rrhcm	553	6	level	level	NN
cord-009417-458rrhcm	553	7	of	of	IN
cord-009417-458rrhcm	553	8	RBC	RBC	NNP
cord-009417-458rrhcm	553	9	-	-	HYPH
cord-009417-458rrhcm	553	10	associated	associate	VBN
cord-009417-458rrhcm	553	11	2,3-DPG	2,3-dpg	CD
cord-009417-458rrhcm	553	12	in	in	IN
cord-009417-458rrhcm	553	13	banked	bank	VBN
cord-009417-458rrhcm	553	14	blood	blood	NN
cord-009417-458rrhcm	553	15	declines	decline	NNS
cord-009417-458rrhcm	553	16	during	during	IN
cord-009417-458rrhcm	553	17	storage	storage	NN
cord-009417-458rrhcm	553	18	,	,	,
cord-009417-458rrhcm	553	19	which	which	WDT
cord-009417-458rrhcm	553	20	increases	increase	VBZ
cord-009417-458rrhcm	553	21	the	the	DT
cord-009417-458rrhcm	553	22	affi	affi	JJ
cord-009417-458rrhcm	553	23	nity	nity	NN
cord-009417-458rrhcm	553	24	of	of	IN
cord-009417-458rrhcm	553	25	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	553	26	for	for	IN
cord-009417-458rrhcm	553	27	oxygen	oxygen	NN
cord-009417-458rrhcm	553	28	and	and	CC
cord-009417-458rrhcm	553	29	thereby	thereby	RB
cord-009417-458rrhcm	553	30	results	result	VBZ
cord-009417-458rrhcm	553	31	in	in	IN
cord-009417-458rrhcm	553	32	decreased	decrease	VBN
cord-009417-458rrhcm	553	33	oxygen	oxygen	NN
cord-009417-458rrhcm	553	34	off	off	RB
cord-009417-458rrhcm	553	35	-	-	HYPH
cord-009417-458rrhcm	553	36	loaded	load	VBN
cord-009417-458rrhcm	553	37	to	to	IN
cord-009417-458rrhcm	553	38	tissues	tissue	NNS
cord-009417-458rrhcm	553	39	.	.	.
cord-009417-458rrhcm	554	1	Even	even	RB
cord-009417-458rrhcm	554	2	in	in	IN
cord-009417-458rrhcm	554	3	massively	massively	RB
cord-009417-458rrhcm	554	4	transfused	transfuse	VBN
cord-009417-458rrhcm	554	5	patients	patient	NNS
cord-009417-458rrhcm	554	6	,	,	,
cord-009417-458rrhcm	554	7	it	-PRON-	PRP
cord-009417-458rrhcm	554	8	has	have	VBZ
cord-009417-458rrhcm	554	9	been	be	VBN
cord-009417-458rrhcm	554	10	diffi	diffi	JJ
cord-009417-458rrhcm	554	11	cult	cult	NN
cord-009417-458rrhcm	554	12	to	to	TO
cord-009417-458rrhcm	554	13	document	document	VB
cord-009417-458rrhcm	554	14	a	a	DT
cord-009417-458rrhcm	554	15	clinical	clinical	JJ
cord-009417-458rrhcm	554	16	impact	impact	NN
cord-009417-458rrhcm	554	17	of	of	IN
cord-009417-458rrhcm	554	18	this	this	DT
cord-009417-458rrhcm	554	19	shift	shift	NN
cord-009417-458rrhcm	554	20	,	,	,
cord-009417-458rrhcm	554	21	and	and	CC
cord-009417-458rrhcm	554	22	no	no	DT
cord-009417-458rrhcm	554	23	reliable	reliable	JJ
cord-009417-458rrhcm	554	24	method	method	NN
cord-009417-458rrhcm	554	25	for	for	IN
cord-009417-458rrhcm	554	26	restoring	restore	VBG
cord-009417-458rrhcm	554	27	red	red	JJ
cord-009417-458rrhcm	554	28	cell	cell	NN
cord-009417-458rrhcm	554	29	2,3-DPG	2,3-dpg	CD
cord-009417-458rrhcm	554	30	has	have	VBZ
cord-009417-458rrhcm	554	31	been	be	VBN
cord-009417-458rrhcm	554	32	developed	develop	VBN
cord-009417-458rrhcm	554	33	.	.	.
cord-009417-458rrhcm	555	1	WB	WB	NNP
cord-009417-458rrhcm	555	2	and	and	CC
cord-009417-458rrhcm	555	3	PRBCs	prbc	NNS
cord-009417-458rrhcm	555	4	are	be	VBP
cord-009417-458rrhcm	555	5	stored	store	VBN
cord-009417-458rrhcm	555	6	at	at	IN
cord-009417-458rrhcm	555	7	approximately	approximately	RB
cord-009417-458rrhcm	555	8	4º	4º	CD
cord-009417-458rrhcm	555	9	C	c	NN
cord-009417-458rrhcm	555	10	and	and	CC
cord-009417-458rrhcm	555	11	require	require	VB
cord-009417-458rrhcm	555	12	30	30	CD
cord-009417-458rrhcm	555	13	to	to	TO
cord-009417-458rrhcm	555	14	45	45	CD
cord-009417-458rrhcm	555	15	minutes	minute	NNS
cord-009417-458rrhcm	555	16	to	to	TO
cord-009417-458rrhcm	555	17	warm	warm	VB
cord-009417-458rrhcm	555	18	to	to	IN
cord-009417-458rrhcm	555	19	room	room	NN
cord-009417-458rrhcm	555	20	temperature	temperature	NN
cord-009417-458rrhcm	555	21	.	.	.
cord-009417-458rrhcm	556	1	Elective	elective	JJ
cord-009417-458rrhcm	556	2	transfusions	transfusion	NNS
cord-009417-458rrhcm	556	3	at	at	IN
cord-009417-458rrhcm	556	4	standard	standard	JJ
cord-009417-458rrhcm	556	5	fl	fl	NNP
cord-009417-458rrhcm	556	6	ow	ow	NN
cord-009417-458rrhcm	556	7	rates	rate	NNS
cord-009417-458rrhcm	556	8	are	be	VBP
cord-009417-458rrhcm	556	9	tolerated	tolerate	VBN
cord-009417-458rrhcm	556	10	without	without	IN
cord-009417-458rrhcm	556	11	the	the	DT
cord-009417-458rrhcm	556	12	need	need	NN
cord-009417-458rrhcm	556	13	to	to	TO
cord-009417-458rrhcm	556	14	warm	warm	VB
cord-009417-458rrhcm	556	15	the	the	DT
cord-009417-458rrhcm	556	16	blood	blood	NN
cord-009417-458rrhcm	556	17	;	;	:
cord-009417-458rrhcm	556	18	however	however	RB
cord-009417-458rrhcm	556	19	,	,	,
cord-009417-458rrhcm	556	20	core	core	NN
cord-009417-458rrhcm	556	21	body	body	NN
cord-009417-458rrhcm	556	22	temperature	temperature	NN
cord-009417-458rrhcm	556	23	,	,	,
cord-009417-458rrhcm	556	24	measured	measure	VBN
cord-009417-458rrhcm	556	25	by	by	IN
cord-009417-458rrhcm	556	26	esophageal	esophageal	JJ
cord-009417-458rrhcm	556	27	probe	probe	NN
cord-009417-458rrhcm	556	28	,	,	,
cord-009417-458rrhcm	556	29	can	can	MD
cord-009417-458rrhcm	556	30	fall	fall	VB
cord-009417-458rrhcm	556	31	to	to	IN
cord-009417-458rrhcm	556	32	30º	30º	NNS
cord-009417-458rrhcm	556	33	C	c	NN
cord-009417-458rrhcm	556	34	or	or	CC
cord-009417-458rrhcm	556	35	lower	low	JJR
cord-009417-458rrhcm	556	36	with	with	IN
cord-009417-458rrhcm	556	37	the	the	DT
cord-009417-458rrhcm	556	38	administration	administration	NN
cord-009417-458rrhcm	556	39	of	of	IN
cord-009417-458rrhcm	556	40	large	large	JJ
cord-009417-458rrhcm	556	41	volumes	volume	NNS
cord-009417-458rrhcm	556	42	of	of	IN
cord-009417-458rrhcm	556	43	cold	cold	JJ
cord-009417-458rrhcm	556	44	blood	blood	NN
cord-009417-458rrhcm	556	45	over	over	IN
cord-009417-458rrhcm	556	46	a	a	DT
cord-009417-458rrhcm	556	47	period	period	NN
cord-009417-458rrhcm	556	48	of	of	IN
cord-009417-458rrhcm	556	49	1	1	CD
cord-009417-458rrhcm	556	50	to	to	IN
cord-009417-458rrhcm	556	51	2	2	CD
cord-009417-458rrhcm	556	52	hours	hour	NNS
cord-009417-458rrhcm	556	53	.	.	.
cord-009417-458rrhcm	557	1	122	122	CD
cord-009417-458rrhcm	557	2	Adverse	adverse	JJ
cord-009417-458rrhcm	557	3	effects	effect	NNS
cord-009417-458rrhcm	557	4	of	of	IN
cord-009417-458rrhcm	557	5	hypothermia	hypothermia	NN
cord-009417-458rrhcm	557	6	include	include	VBP
cord-009417-458rrhcm	557	7	a	a	DT
cord-009417-458rrhcm	557	8	decreased	decrease	VBN
cord-009417-458rrhcm	557	9	heart	heart	NN
cord-009417-458rrhcm	557	10	rate	rate	NN
cord-009417-458rrhcm	557	11	and	and	CC
cord-009417-458rrhcm	557	12	myocardial	myocardial	JJ
cord-009417-458rrhcm	557	13	contractility	contractility	NN
cord-009417-458rrhcm	557	14	,	,	,
cord-009417-458rrhcm	557	15	cardiac	cardiac	NN
cord-009417-458rrhcm	557	16	arrhythmias	arrhythmia	NNS
cord-009417-458rrhcm	557	17	,	,	,
cord-009417-458rrhcm	557	18	increased	increase	VBD
cord-009417-458rrhcm	557	19	affi	affi	NNP
cord-009417-458rrhcm	557	20	nity	nity	NN
cord-009417-458rrhcm	557	21	of	of	IN
cord-009417-458rrhcm	557	22	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	557	23	for	for	IN
cord-009417-458rrhcm	557	24	oxygen	oxygen	NN
cord-009417-458rrhcm	557	25	resulting	result	VBG
cord-009417-458rrhcm	557	26	in	in	IN
cord-009417-458rrhcm	557	27	decreased	decreased	JJ
cord-009417-458rrhcm	557	28	tissue	tissue	NN
cord-009417-458rrhcm	557	29	oxygen	oxygen	NN
cord-009417-458rrhcm	557	30	delivery	delivery	NN
cord-009417-458rrhcm	557	31	,	,	,
cord-009417-458rrhcm	557	32	DIC	DIC	NNP
cord-009417-458rrhcm	557	33	,	,	,
cord-009417-458rrhcm	557	34	and	and	CC
cord-009417-458rrhcm	557	35	impaired	impaired	JJ
cord-009417-458rrhcm	557	36	ability	ability	NN
cord-009417-458rrhcm	557	37	to	to	TO
cord-009417-458rrhcm	557	38	metabolize	metabolize	VB
cord-009417-458rrhcm	557	39	the	the	DT
cord-009417-458rrhcm	557	40	citrate	citrate	NN
cord-009417-458rrhcm	557	41	load	load	NN
cord-009417-458rrhcm	557	42	of	of	IN
cord-009417-458rrhcm	557	43	stored	store	VBN
cord-009417-458rrhcm	557	44	blood	blood	NN
cord-009417-458rrhcm	557	45	.	.	.
cord-009417-458rrhcm	558	1	Both	both	DT
cord-009417-458rrhcm	558	2	blood	blood	NN
cord-009417-458rrhcm	558	3	warmers	warmer	NNS
cord-009417-458rrhcm	558	4	and	and	CC
cord-009417-458rrhcm	558	5	patient	patient	JJ
cord-009417-458rrhcm	558	6	warming	warming	NN
cord-009417-458rrhcm	558	7	may	may	MD
cord-009417-458rrhcm	558	8	be	be	VB
cord-009417-458rrhcm	558	9	instituted	institute	VBN
cord-009417-458rrhcm	558	10	during	during	IN
cord-009417-458rrhcm	558	11	massive	massive	JJ
cord-009417-458rrhcm	558	12	transfusion	transfusion	NN
cord-009417-458rrhcm	558	13	,	,	,
cord-009417-458rrhcm	558	14	and	and	CC
cord-009417-458rrhcm	558	15	patient	patient	JJ
cord-009417-458rrhcm	558	16	core	core	NN
cord-009417-458rrhcm	558	17	temperature	temperature	NN
cord-009417-458rrhcm	558	18	should	should	MD
cord-009417-458rrhcm	558	19	be	be	VB
cord-009417-458rrhcm	558	20	monitored	monitor	VBN
cord-009417-458rrhcm	558	21	during	during	IN
cord-009417-458rrhcm	558	22	such	such	JJ
cord-009417-458rrhcm	558	23	resuscitative	resuscitative	JJ
cord-009417-458rrhcm	558	24	efforts	effort	NNS
cord-009417-458rrhcm	558	25	.	.	.
cord-009417-458rrhcm	559	1	Whether	whether	IN
cord-009417-458rrhcm	559	2	massive	massive	JJ
cord-009417-458rrhcm	559	3	transfusion	transfusion	NN
cord-009417-458rrhcm	559	4	in	in	IN
cord-009417-458rrhcm	559	5	and	and	CC
cord-009417-458rrhcm	559	6	of	of	IN
cord-009417-458rrhcm	559	7	itself	-PRON-	PRP
cord-009417-458rrhcm	559	8	is	be	VBZ
cord-009417-458rrhcm	559	9	a	a	DT
cord-009417-458rrhcm	559	10	cause	cause	NN
cord-009417-458rrhcm	559	11	of	of	IN
cord-009417-458rrhcm	559	12	ARDS	ARDS	NNP
cord-009417-458rrhcm	559	13	is	be	VBZ
cord-009417-458rrhcm	559	14	another	another	DT
cord-009417-458rrhcm	559	15	source	source	NN
cord-009417-458rrhcm	559	16	of	of	IN
cord-009417-458rrhcm	559	17	controversy	controversy	NN
cord-009417-458rrhcm	559	18	.	.	.
cord-009417-458rrhcm	560	1	There	there	EX
cord-009417-458rrhcm	560	2	are	be	VBP
cord-009417-458rrhcm	560	3	certainly	certainly	RB
cord-009417-458rrhcm	560	4	theoretical	theoretical	JJ
cord-009417-458rrhcm	560	5	reasons	reason	NNS
cord-009417-458rrhcm	560	6	why	why	WRB
cord-009417-458rrhcm	560	7	massive	massive	JJ
cord-009417-458rrhcm	560	8	transfusion	transfusion	NN
cord-009417-458rrhcm	560	9	might	may	MD
cord-009417-458rrhcm	560	10	precipitate	precipitate	VB
cord-009417-458rrhcm	560	11	ARDS	ARDS	NNP
cord-009417-458rrhcm	560	12	:	:	:
cord-009417-458rrhcm	561	1	all	all	DT
cord-009417-458rrhcm	561	2	cellular	cellular	JJ
cord-009417-458rrhcm	561	3	transfusions	transfusion	NNS
cord-009417-458rrhcm	561	4	contain	contain	VBP
cord-009417-458rrhcm	561	5	damaged	damage	VBN
cord-009417-458rrhcm	561	6	or	or	CC
cord-009417-458rrhcm	561	7	activated	activate	VBN
cord-009417-458rrhcm	561	8	WBCs	wbc	NNS
cord-009417-458rrhcm	561	9	,	,	,
cord-009417-458rrhcm	561	10	cell	cell	NN
cord-009417-458rrhcm	561	11	membranes	membrane	NNS
cord-009417-458rrhcm	561	12	,	,	,
cord-009417-458rrhcm	561	13	aggregated	aggregate	VBN
cord-009417-458rrhcm	561	14	platelets	platelet	NNS
cord-009417-458rrhcm	561	15	,	,	,
cord-009417-458rrhcm	561	16	and	and	CC
cord-009417-458rrhcm	561	17	microthrombi	microthrombi	NNP
cord-009417-458rrhcm	561	18	,	,	,
cord-009417-458rrhcm	561	19	all	all	DT
cord-009417-458rrhcm	561	20	of	of	IN
cord-009417-458rrhcm	561	21	which	which	WDT
cord-009417-458rrhcm	561	22	are	be	VBP
cord-009417-458rrhcm	561	23	capable	capable	JJ
cord-009417-458rrhcm	561	24	of	of	IN
cord-009417-458rrhcm	561	25	lodging	lodge	VBG
cord-009417-458rrhcm	561	26	in	in	IN
cord-009417-458rrhcm	561	27	and	and	CC
cord-009417-458rrhcm	561	28	damaging	damaging	JJ
cord-009417-458rrhcm	561	29	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	561	30	capillaries	capillary	NNS
cord-009417-458rrhcm	561	31	.	.	.
cord-009417-458rrhcm	562	1	Despite	despite	IN
cord-009417-458rrhcm	562	2	this	this	DT
cord-009417-458rrhcm	562	3	possibility	possibility	NN
cord-009417-458rrhcm	562	4	,	,	,
cord-009417-458rrhcm	562	5	neither	neither	CC
cord-009417-458rrhcm	562	6	microfi	microfi	NNP
cord-009417-458rrhcm	562	7	ltration	ltration	NN
cord-009417-458rrhcm	562	8	of	of	IN
cord-009417-458rrhcm	562	9	transfusions	transfusion	NNS
cord-009417-458rrhcm	562	10	nor	nor	CC
cord-009417-458rrhcm	562	11	routine	routine	JJ
cord-009417-458rrhcm	562	12	leukocyte	leukocyte	NN
cord-009417-458rrhcm	562	13	depletion	depletion	NN
cord-009417-458rrhcm	562	14	has	have	VBZ
cord-009417-458rrhcm	562	15	shown	show	VBN
cord-009417-458rrhcm	562	16	a	a	DT
cord-009417-458rrhcm	562	17	signifi	signifi	NN
cord-009417-458rrhcm	562	18	ca	can	MD
cord-009417-458rrhcm	562	19	nt	not	RB
cord-009417-458rrhcm	562	20	impact	impact	VB
cord-009417-458rrhcm	562	21	on	on	IN
cord-009417-458rrhcm	562	22	the	the	DT
cord-009417-458rrhcm	562	23	incidence	incidence	NN
cord-009417-458rrhcm	562	24	of	of	IN
cord-009417-458rrhcm	562	25	ARDS	ARDS	NNP
cord-009417-458rrhcm	562	26	in	in	IN
cord-009417-458rrhcm	562	27	massively	massively	RB
cord-009417-458rrhcm	562	28	transfused	transfuse	VBN
cord-009417-458rrhcm	562	29	patients	patient	NNS
cord-009417-458rrhcm	562	30	.	.	.
cord-009417-458rrhcm	563	1	123	123	CD
cord-009417-458rrhcm	564	1	Certainly	certainly	RB
cord-009417-458rrhcm	564	2	,	,	,
cord-009417-458rrhcm	564	3	other	other	JJ
cord-009417-458rrhcm	564	4	causes	cause	NNS
cord-009417-458rrhcm	564	5	of	of	IN
cord-009417-458rrhcm	564	6	ARDS	ARDS	NNP
cord-009417-458rrhcm	564	7	exist	exist	VBP
cord-009417-458rrhcm	564	8	in	in	IN
cord-009417-458rrhcm	564	9	patients	patient	NNS
cord-009417-458rrhcm	564	10	who	who	WP
cord-009417-458rrhcm	564	11	undergo	undergo	VBP
cord-009417-458rrhcm	564	12	massive	massive	JJ
cord-009417-458rrhcm	564	13	transfusion	transfusion	NN
cord-009417-458rrhcm	564	14	,	,	,
cord-009417-458rrhcm	564	15	and	and	CC
cord-009417-458rrhcm	564	16	the	the	DT
cord-009417-458rrhcm	564	17	possibility	possibility	NN
cord-009417-458rrhcm	564	18	of	of	IN
cord-009417-458rrhcm	564	19	volume	volume	NN
cord-009417-458rrhcm	564	20	overload	overload	NN
cord-009417-458rrhcm	564	21	and	and	CC
cord-009417-458rrhcm	564	22	TRALI	TRALI	NNP
cord-009417-458rrhcm	564	23	should	should	MD
cord-009417-458rrhcm	564	24	be	be	VB
cord-009417-458rrhcm	564	25	considered	consider	VBN
cord-009417-458rrhcm	564	26	in	in	IN
cord-009417-458rrhcm	564	27	the	the	DT
cord-009417-458rrhcm	564	28	evaluation	evaluation	NN
cord-009417-458rrhcm	564	29	of	of	IN
cord-009417-458rrhcm	564	30	patients	patient	NNS
cord-009417-458rrhcm	564	31	with	with	IN
cord-009417-458rrhcm	564	32	hypoxia	hypoxia	NN
cord-009417-458rrhcm	564	33	and	and	CC
cord-009417-458rrhcm	564	34	diffuse	diffuse	VB
cord-009417-458rrhcm	564	35	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	564	36	infi	infi	NNP
cord-009417-458rrhcm	564	37	ltrates	ltrates	NNP
cord-009417-458rrhcm	564	38	after	after	IN
cord-009417-458rrhcm	564	39	massive	massive	JJ
cord-009417-458rrhcm	564	40	transfusion	transfusion	NN
cord-009417-458rrhcm	564	41	.	.	.
cord-009417-458rrhcm	565	1	Management	management	NN
cord-009417-458rrhcm	565	2	of	of	IN
cord-009417-458rrhcm	565	3	such	such	JJ
cord-009417-458rrhcm	565	4	patients	patient	NNS
cord-009417-458rrhcm	565	5	is	be	VBZ
cord-009417-458rrhcm	565	6	supportive	supportive	JJ
cord-009417-458rrhcm	565	7	,	,	,
cord-009417-458rrhcm	565	8	consistent	consistent	JJ
cord-009417-458rrhcm	565	9	with	with	IN
cord-009417-458rrhcm	565	10	the	the	DT
cord-009417-458rrhcm	565	11	overall	overall	JJ
cord-009417-458rrhcm	565	12	management	management	NN
cord-009417-458rrhcm	565	13	of	of	IN
cord-009417-458rrhcm	565	14	massive	massive	JJ
cord-009417-458rrhcm	565	15	transfusion	transfusion	NN
cord-009417-458rrhcm	565	16	.	.	.
cord-009417-458rrhcm	566	1	124	124	CD
cord-009417-458rrhcm	566	2	,	,	,
cord-009417-458rrhcm	566	3	125	125	CD
cord-009417-458rrhcm	566	4	Autoimmune	autoimmune	JJ
cord-009417-458rrhcm	566	5	Hemolytic	hemolytic	JJ
cord-009417-458rrhcm	566	6	Anemia	anemia	NN
cord-009417-458rrhcm	566	7	Patients	patient	NNS
cord-009417-458rrhcm	566	8	with	with	IN
cord-009417-458rrhcm	566	9	autoimmune	autoimmune	JJ
cord-009417-458rrhcm	566	10	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	566	11	anemia	anemia	NN
cord-009417-458rrhcm	566	12	(	(	-LRB-
cord-009417-458rrhcm	566	13	AIHA	AIHA	NNP
cord-009417-458rrhcm	566	14	)	)	-RRB-
cord-009417-458rrhcm	566	15	have	have	VB
cord-009417-458rrhcm	566	16	an	an	DT
cord-009417-458rrhcm	566	17	autoantibody	autoantibody	NN
cord-009417-458rrhcm	566	18	,	,	,
cord-009417-458rrhcm	566	19	usually	usually	RB
cord-009417-458rrhcm	566	20	of	of	IN
cord-009417-458rrhcm	566	21	broad	broad	JJ
cord-009417-458rrhcm	566	22	specifi	specifi	NN
cord-009417-458rrhcm	566	23	city	city	NN
cord-009417-458rrhcm	566	24	,	,	,
cord-009417-458rrhcm	567	1	that	that	IN
cord-009417-458rrhcm	567	2	fi	fi	NNP
cord-009417-458rrhcm	567	3	xes	xes	NN
cord-009417-458rrhcm	567	4	itself	-PRON-	PRP
cord-009417-458rrhcm	567	5	to	to	IN
cord-009417-458rrhcm	567	6	their	-PRON-	PRP$
cord-009417-458rrhcm	567	7	RBCs	rbc	NNS
cord-009417-458rrhcm	567	8	and	and	CC
cord-009417-458rrhcm	567	9	triggers	trigger	VBZ
cord-009417-458rrhcm	567	10	extravascular	extravascular	JJ
cord-009417-458rrhcm	567	11	immune	immune	JJ
cord-009417-458rrhcm	567	12	-	-	HYPH
cord-009417-458rrhcm	567	13	mediated	mediate	VBN
cord-009417-458rrhcm	567	14	destruction	destruction	NN
cord-009417-458rrhcm	567	15	.	.	.
cord-009417-458rrhcm	568	1	Patients	patient	NNS
cord-009417-458rrhcm	568	2	with	with	IN
cord-009417-458rrhcm	568	3	AIHA	AIHA	NNP
cord-009417-458rrhcm	568	4	have	have	VBP
cord-009417-458rrhcm	568	5	a	a	DT
cord-009417-458rrhcm	568	6	positive	positive	JJ
cord-009417-458rrhcm	568	7	direct	direct	JJ
cord-009417-458rrhcm	568	8	antiglobulin	antiglobulin	NN
cord-009417-458rrhcm	568	9	test	test	NN
cord-009417-458rrhcm	568	10	126	126	CD
cord-009417-458rrhcm	568	11	(	(	-LRB-
cord-009417-458rrhcm	568	12	DAT	DAT	NNP
cord-009417-458rrhcm	568	13	,	,	,
cord-009417-458rrhcm	568	14	commonly	commonly	RB
cord-009417-458rrhcm	568	15	known	know	VBN
cord-009417-458rrhcm	568	16	as	as	IN
cord-009417-458rrhcm	568	17	the	the	DT
cord-009417-458rrhcm	568	18	Coombs	Coombs	NNP
cord-009417-458rrhcm	568	19	test	test	NN
cord-009417-458rrhcm	568	20	)	)	-RRB-
cord-009417-458rrhcm	568	21	and	and	CC
cord-009417-458rrhcm	568	22	varying	vary	VBG
cord-009417-458rrhcm	568	23	degrees	degree	NNS
cord-009417-458rrhcm	568	24	of	of	IN
cord-009417-458rrhcm	568	25	he	-PRON-	PRP
cord-009417-458rrhcm	568	26	molysis	molysis	NN
cord-009417-458rrhcm	568	27	,	,	,
cord-009417-458rrhcm	568	28	and	and	CC
cord-009417-458rrhcm	568	29	their	-PRON-	PRP$
cord-009417-458rrhcm	568	30	autoantibodies	autoantibody	NNS
cord-009417-458rrhcm	568	31	cause	cause	VBP
cord-009417-458rrhcm	568	32	agglutination	agglutination	NN
cord-009417-458rrhcm	568	33	of	of	IN
cord-009417-458rrhcm	568	34	RBCs	rbc	NNS
cord-009417-458rrhcm	568	35	from	from	IN
cord-009417-458rrhcm	568	36	all	all	DT
cord-009417-458rrhcm	568	37	donors	donor	NNS
cord-009417-458rrhcm	568	38	during	during	IN
cord-009417-458rrhcm	568	39	crossmatching	crossmatching	NN
cord-009417-458rrhcm	568	40	.	.	.
cord-009417-458rrhcm	569	1	If	if	IN
cord-009417-458rrhcm	569	2	the	the	DT
cord-009417-458rrhcm	569	3	hemolysis	hemolysis	NN
cord-009417-458rrhcm	569	4	is	be	VBZ
cord-009417-458rrhcm	569	5	brisk	brisk	JJ
cord-009417-458rrhcm	569	6	,	,	,
cord-009417-458rrhcm	569	7	patients	patient	NNS
cord-009417-458rrhcm	569	8	may	may	MD
cord-009417-458rrhcm	569	9	require	require	VB
cord-009417-458rrhcm	569	10	red	red	JJ
cord-009417-458rrhcm	569	11	cell	cell	NN
cord-009417-458rrhcm	569	12	transfusion	transfusion	NN
cord-009417-458rrhcm	569	13	to	to	TO
cord-009417-458rrhcm	569	14	support	support	VB
cord-009417-458rrhcm	569	15	oxygen	oxygen	NN
cord-009417-458rrhcm	569	16	needs	need	NNS
cord-009417-458rrhcm	569	17	before	before	IN
cord-009417-458rrhcm	569	18	medical	medical	JJ
cord-009417-458rrhcm	569	19	management	management	NN
cord-009417-458rrhcm	569	20	of	of	IN
cord-009417-458rrhcm	569	21	the	the	DT
cord-009417-458rrhcm	569	22	AIHA	AIHA	NNP
cord-009417-458rrhcm	569	23	is	be	VBZ
cord-009417-458rrhcm	569	24	effective	effective	JJ
cord-009417-458rrhcm	569	25	.	.	.
cord-009417-458rrhcm	570	1	Hence	hence	RB
cord-009417-458rrhcm	570	2	,	,	,
cord-009417-458rrhcm	570	3	transfusion	transfusion	NN
cord-009417-458rrhcm	570	4	is	be	VBZ
cord-009417-458rrhcm	570	5	diffi	diffi	JJ
cord-009417-458rrhcm	570	6	cult	cult	NN
cord-009417-458rrhcm	570	7	because	because	IN
cord-009417-458rrhcm	570	8	agglutination	agglutination	NN
cord-009417-458rrhcm	570	9	during	during	IN
cord-009417-458rrhcm	570	10	crossmatching	crossmatching	NN
cord-009417-458rrhcm	570	11	interferes	interfere	VBZ
cord-009417-458rrhcm	570	12	with	with	IN
cord-009417-458rrhcm	570	13	proper	proper	JJ
cord-009417-458rrhcm	570	14	defi	defi	NNP
cord-009417-458rrhcm	570	15	nition	nition	NN
cord-009417-458rrhcm	570	16	of	of	IN
cord-009417-458rrhcm	570	17	compatible	compatible	JJ
cord-009417-458rrhcm	570	18	units	unit	NNS
cord-009417-458rrhcm	570	19	of	of	IN
cord-009417-458rrhcm	570	20	RBCs	rbc	NNS
cord-009417-458rrhcm	570	21	and	and	CC
cord-009417-458rrhcm	570	22	because	because	IN
cord-009417-458rrhcm	570	23	the	the	DT
cord-009417-458rrhcm	570	24	transfused	transfuse	VBN
cord-009417-458rrhcm	570	25	RBCs	rbc	NNS
cord-009417-458rrhcm	570	26	are	be	VBP
cord-009417-458rrhcm	570	27	themselves	-PRON-	PRP
cord-009417-458rrhcm	570	28	subject	subject	JJ
cord-009417-458rrhcm	570	29	to	to	IN
cord-009417-458rrhcm	570	30	the	the	DT
cord-009417-458rrhcm	570	31	same	same	JJ
cord-009417-458rrhcm	570	32	immune	immune	JJ
cord-009417-458rrhcm	570	33	hemolysis	hemolysis	NN
cord-009417-458rrhcm	570	34	as	as	IN
cord-009417-458rrhcm	570	35	the	the	DT
cord-009417-458rrhcm	570	36	host	host	NN
cord-009417-458rrhcm	570	37	RBCs	rbc	NNS
cord-009417-458rrhcm	570	38	.	.	.
cord-009417-458rrhcm	571	1	Many	many	JJ
cord-009417-458rrhcm	571	2	blood	blood	NN
cord-009417-458rrhcm	571	3	banks	bank	NNS
cord-009417-458rrhcm	571	4	have	have	VBP
cord-009417-458rrhcm	571	5	methods	method	NNS
cord-009417-458rrhcm	571	6	for	for	IN
cord-009417-458rrhcm	571	7	depletion	depletion	NN
cord-009417-458rrhcm	571	8	of	of	IN
cord-009417-458rrhcm	571	9	autoantibodies	autoantibody	NNS
cord-009417-458rrhcm	571	10	from	from	IN
cord-009417-458rrhcm	571	11	the	the	DT
cord-009417-458rrhcm	571	12	recipient	recipient	NN
cord-009417-458rrhcm	571	13	's	's	POS
cord-009417-458rrhcm	571	14	plasma	plasma	NN
cord-009417-458rrhcm	571	15	and	and	CC
cord-009417-458rrhcm	571	16	elution	elution	NN
cord-009417-458rrhcm	571	17	of	of	IN
cord-009417-458rrhcm	571	18	antibodies	antibody	NNS
cord-009417-458rrhcm	571	19	from	from	IN
cord-009417-458rrhcm	571	20	RBCs	rbc	NNS
cord-009417-458rrhcm	571	21	to	to	TO
cord-009417-458rrhcm	571	22	arrive	arrive	VB
cord-009417-458rrhcm	571	23	at	at	IN
cord-009417-458rrhcm	571	24	a	a	DT
cord-009417-458rrhcm	571	25	proper	proper	JJ
cord-009417-458rrhcm	571	26	crossmatch	crossmatch	NN
cord-009417-458rrhcm	571	27	.	.	.
cord-009417-458rrhcm	572	1	127	127	CD
cord-009417-458rrhcm	573	1	Although	although	IN
cord-009417-458rrhcm	573	2	such	such	JJ
cord-009417-458rrhcm	573	3	crossmatches	crossmatche	NNS
cord-009417-458rrhcm	573	4	are	be	VBP
cord-009417-458rrhcm	573	5	time	time	NN
cord-009417-458rrhcm	573	6	consuming	consume	VBG
cord-009417-458rrhcm	573	7	and	and	CC
cord-009417-458rrhcm	573	8	not	not	RB
cord-009417-458rrhcm	573	9	generally	generally	RB
cord-009417-458rrhcm	573	10	available	available	JJ
cord-009417-458rrhcm	573	11	on	on	IN
cord-009417-458rrhcm	573	12	an	an	DT
cord-009417-458rrhcm	573	13	emergency	emergency	NN
cord-009417-458rrhcm	573	14	basis	basis	NN
cord-009417-458rrhcm	573	15	,	,	,
cord-009417-458rrhcm	573	16	they	-PRON-	PRP
cord-009417-458rrhcm	573	17	can	can	MD
cord-009417-458rrhcm	573	18	be	be	VB
cord-009417-458rrhcm	573	19	lifesaving	lifesave	VBG
cord-009417-458rrhcm	573	20	.	.	.
cord-009417-458rrhcm	574	1	Criteria	criterion	NNS
cord-009417-458rrhcm	574	2	for	for	IN
cord-009417-458rrhcm	574	3	transfusion	transfusion	NN
cord-009417-458rrhcm	574	4	should	should	MD
cord-009417-458rrhcm	574	5	remain	remain	VB
cord-009417-458rrhcm	574	6	the	the	DT
cord-009417-458rrhcm	574	7	same	same	JJ
cord-009417-458rrhcm	574	8	as	as	IN
cord-009417-458rrhcm	574	9	for	for	IN
cord-009417-458rrhcm	574	10	other	other	JJ
cord-009417-458rrhcm	574	11	recipients	recipient	NNS
cord-009417-458rrhcm	574	12	.	.	.
cord-009417-458rrhcm	575	1	RBCs	rbc	NNS
cord-009417-458rrhcm	575	2	are	be	VBP
cord-009417-458rrhcm	575	3	crossmatched	crossmatche	VBN
cord-009417-458rrhcm	575	4	for	for	IN
cord-009417-458rrhcm	575	5	red	red	JJ
cord-009417-458rrhcm	575	6	cell	cell	NN
cord-009417-458rrhcm	575	7	antigens	antigen	NNS
cord-009417-458rrhcm	575	8	in	in	IN
cord-009417-458rrhcm	575	9	the	the	DT
cord-009417-458rrhcm	575	10	ABO	ABO	NNP
cord-009417-458rrhcm	575	11	and	and	CC
cord-009417-458rrhcm	575	12	Rh	Rh	NNP
cord-009417-458rrhcm	575	13	0	0	NFP
cord-009417-458rrhcm	575	14	(	(	-LRB-
cord-009417-458rrhcm	575	15	D	D	NNP
cord-009417-458rrhcm	575	16	)	)	-RRB-
cord-009417-458rrhcm	575	17	group	group	NN
cord-009417-458rrhcm	575	18	and	and	CC
cord-009417-458rrhcm	575	19	for	for	IN
cord-009417-458rrhcm	575	20	other	other	JJ
cord-009417-458rrhcm	575	21	red	red	JJ
cord-009417-458rrhcm	575	22	cell	cell	NN
cord-009417-458rrhcm	575	23	antigens	antigen	NNS
cord-009417-458rrhcm	575	24	when	when	WRB
cord-009417-458rrhcm	575	25	antibodies	antibody	NNS
cord-009417-458rrhcm	575	26	are	be	VBP
cord-009417-458rrhcm	575	27	present	present	JJ
cord-009417-458rrhcm	575	28	.	.	.
cord-009417-458rrhcm	576	1	However	however	RB
cord-009417-458rrhcm	576	2	,	,	,
cord-009417-458rrhcm	576	3	there	there	EX
cord-009417-458rrhcm	576	4	are	be	VBP
cord-009417-458rrhcm	576	5	several	several	JJ
cord-009417-458rrhcm	576	6	hundred	hundred	CD
cord-009417-458rrhcm	576	7	other	other	JJ
cord-009417-458rrhcm	576	8	red	red	JJ
cord-009417-458rrhcm	576	9	cell	cell	NN
cord-009417-458rrhcm	576	10	antigens	antigen	NNS
cord-009417-458rrhcm	576	11	in	in	IN
cord-009417-458rrhcm	576	12	the	the	DT
cord-009417-458rrhcm	576	13	human	human	JJ
cord-009417-458rrhcm	576	14	family	family	NN
cord-009417-458rrhcm	576	15	,	,	,
cord-009417-458rrhcm	576	16	and	and	CC
cord-009417-458rrhcm	576	17	with	with	IN
cord-009417-458rrhcm	576	18	repeated	repeat	VBN
cord-009417-458rrhcm	576	19	transfusion	transfusion	NN
cord-009417-458rrhcm	576	20	recipients	recipient	NNS
cord-009417-458rrhcm	576	21	may	may	MD
cord-009417-458rrhcm	576	22	become	become	VB
cord-009417-458rrhcm	576	23	alloimmunized	alloimmunize	VBN
cord-009417-458rrhcm	576	24	to	to	IN
cord-009417-458rrhcm	576	25	other	other	JJ
cord-009417-458rrhcm	576	26	antigens	antigen	NNS
cord-009417-458rrhcm	576	27	.	.	.
cord-009417-458rrhcm	577	1	Generally	generally	RB
cord-009417-458rrhcm	577	2	,	,	,
cord-009417-458rrhcm	577	3	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	577	4	occurs	occur	VBZ
cord-009417-458rrhcm	577	5	in	in	IN
cord-009417-458rrhcm	577	6	approximately	approximately	RB
cord-009417-458rrhcm	577	7	1	1	CD
cord-009417-458rrhcm	577	8	%	%	NN
cord-009417-458rrhcm	577	9	of	of	IN
cord-009417-458rrhcm	577	10	transfusions	transfusion	NNS
cord-009417-458rrhcm	577	11	,	,	,
cord-009417-458rrhcm	577	12	68	68	CD
cord-009417-458rrhcm	577	13	but	but	CC
cord-009417-458rrhcm	577	14	the	the	DT
cord-009417-458rrhcm	577	15	prevalence	prevalence	NN
cord-009417-458rrhcm	577	16	of	of	IN
cord-009417-458rrhcm	577	17	alloantibodies	alloantibody	NNS
cord-009417-458rrhcm	577	18	is	be	VBZ
cord-009417-458rrhcm	577	19	higher	high	JJR
cord-009417-458rrhcm	577	20	in	in	IN
cord-009417-458rrhcm	577	21	chronically	chronically	RB
cord-009417-458rrhcm	577	22	transfused	transfuse	VBN
cord-009417-458rrhcm	577	23	,	,	,
cord-009417-458rrhcm	577	24	relatively	relatively	RB
cord-009417-458rrhcm	577	25	immunocompetent	immunocompetent	JJ
cord-009417-458rrhcm	577	26	patients	patient	NNS
cord-009417-458rrhcm	577	27	,	,	,
cord-009417-458rrhcm	577	28	especially	especially	RB
cord-009417-458rrhcm	577	29	African	African	NNPS
cord-009417-458rrhcm	577	30	Americans	Americans	NNPS
cord-009417-458rrhcm	577	31	,	,	,
cord-009417-458rrhcm	577	32	whose	whose	WP$
cord-009417-458rrhcm	577	33	distribution	distribution	NN
cord-009417-458rrhcm	577	34	of	of	IN
cord-009417-458rrhcm	577	35	red	red	JJ
cord-009417-458rrhcm	577	36	cell	cell	NN
cord-009417-458rrhcm	577	37	antigens	antigen	NNS
cord-009417-458rrhcm	577	38	has	have	VBZ
cord-009417-458rrhcm	577	39	signifi	signifi	NNP
cord-009417-458rrhcm	577	40	ca	can	MD
cord-009417-458rrhcm	577	41	nt	not	RB
cord-009417-458rrhcm	577	42	variation	variation	NN
cord-009417-458rrhcm	577	43	from	from	IN
cord-009417-458rrhcm	577	44	the	the	DT
cord-009417-458rrhcm	577	45	white	white	JJ
cord-009417-458rrhcm	577	46	population	population	NN
cord-009417-458rrhcm	577	47	.	.	.
cord-009417-458rrhcm	578	1	Alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	578	2	rates	rate	NNS
cord-009417-458rrhcm	578	3	of	of	IN
cord-009417-458rrhcm	578	4	30	30	CD
cord-009417-458rrhcm	578	5	%	%	NN
cord-009417-458rrhcm	578	6	or	or	CC
cord-009417-458rrhcm	578	7	higher	high	JJR
cord-009417-458rrhcm	578	8	may	may	MD
cord-009417-458rrhcm	578	9	be	be	VB
cord-009417-458rrhcm	578	10	found	find	VBN
cord-009417-458rrhcm	578	11	in	in	IN
cord-009417-458rrhcm	578	12	chronically	chronically	RB
cord-009417-458rrhcm	578	13	transfused	transfuse	VBN
cord-009417-458rrhcm	578	14	patients	patient	NNS
cord-009417-458rrhcm	578	15	with	with	IN
cord-009417-458rrhcm	578	16	hemoglobinopathies	hemoglobinopathy	NNS
cord-009417-458rrhcm	578	17	who	who	WP
cord-009417-458rrhcm	578	18	have	have	VBP
cord-009417-458rrhcm	578	19	not	not	RB
cord-009417-458rrhcm	578	20	received	receive	VBN
cord-009417-458rrhcm	578	21	RBCs	rbc	NNS
cord-009417-458rrhcm	578	22	matched	match	VBN
cord-009417-458rrhcm	578	23	to	to	IN
cord-009417-458rrhcm	578	24	potent	potent	JJ
cord-009417-458rrhcm	578	25	minor	minor	JJ
cord-009417-458rrhcm	578	26	antigens	antigen	NNS
cord-009417-458rrhcm	578	27	such	such	JJ
cord-009417-458rrhcm	578	28	as	as	IN
cord-009417-458rrhcm	578	29	Kell	Kell	NNP
cord-009417-458rrhcm	578	30	,	,	,
cord-009417-458rrhcm	578	31	Duffy	Duffy	NNP
cord-009417-458rrhcm	578	32	,	,	,
cord-009417-458rrhcm	578	33	and	and	CC
cord-009417-458rrhcm	578	34	Lewis	Lewis	NNP
cord-009417-458rrhcm	578	35	.	.	.
cord-009417-458rrhcm	579	1	Alloimmunization	Alloimmunization	NNP
cord-009417-458rrhcm	579	2	may	may	MD
cord-009417-458rrhcm	579	3	present	present	VB
cord-009417-458rrhcm	579	4	diffi	diffi	NNP
cord-009417-458rrhcm	579	5	culties	cultie	NNS
cord-009417-458rrhcm	579	6	in	in	IN
cord-009417-458rrhcm	579	7	crossmatching	crossmatching	NN
cord-009417-458rrhcm	579	8	of	of	IN
cord-009417-458rrhcm	579	9	blood	blood	NN
cord-009417-458rrhcm	579	10	,	,	,
cord-009417-458rrhcm	579	11	to	to	IN
cord-009417-458rrhcm	579	12	the	the	DT
cord-009417-458rrhcm	579	13	point	point	NN
cord-009417-458rrhcm	579	14	that	that	IN
cord-009417-458rrhcm	579	15	compatible	compatible	JJ
cord-009417-458rrhcm	579	16	blood	blood	NN
cord-009417-458rrhcm	579	17	must	must	MD
cord-009417-458rrhcm	579	18	be	be	VB
cord-009417-458rrhcm	579	19	obtained	obtain	VBN
cord-009417-458rrhcm	579	20	from	from	IN
cord-009417-458rrhcm	579	21	raredonor	raredonor	NNP
cord-009417-458rrhcm	579	22	registries	registry	NNS
cord-009417-458rrhcm	579	23	,	,	,
cord-009417-458rrhcm	579	24	if	if	IN
cord-009417-458rrhcm	579	25	at	at	RB
cord-009417-458rrhcm	579	26	all	all	RB
cord-009417-458rrhcm	579	27	.	.	.
cord-009417-458rrhcm	580	1	Other	other	JJ
cord-009417-458rrhcm	580	2	patients	patient	NNS
cord-009417-458rrhcm	580	3	present	present	VBP
cord-009417-458rrhcm	580	4	unresolved	unresolved	JJ
cord-009417-458rrhcm	580	5	serologic	serologic	NN
cord-009417-458rrhcm	580	6	problems	problem	NNS
cord-009417-458rrhcm	580	7	in	in	IN
cord-009417-458rrhcm	580	8	that	that	IN
cord-009417-458rrhcm	580	9	the	the	DT
cord-009417-458rrhcm	580	10	alloantibody	alloantibody	NN
cord-009417-458rrhcm	580	11	is	be	VBZ
cord-009417-458rrhcm	580	12	never	never	RB
cord-009417-458rrhcm	580	13	precisely	precisely	RB
cord-009417-458rrhcm	580	14	identifi	identifi	NNP
cord-009417-458rrhcm	580	15	ed	ed	NN
cord-009417-458rrhcm	581	1	yet	yet	RB
cord-009417-458rrhcm	581	2	the	the	DT
cord-009417-458rrhcm	581	3	majority	majority	NN
cord-009417-458rrhcm	581	4	of	of	IN
cord-009417-458rrhcm	581	5	blood	blood	NN
cord-009417-458rrhcm	581	6	available	available	JJ
cord-009417-458rrhcm	581	7	for	for	IN
cord-009417-458rrhcm	581	8	transfusion	transfusion	NN
cord-009417-458rrhcm	581	9	is	be	VBZ
cord-009417-458rrhcm	581	10	incompatible	incompatible	JJ
cord-009417-458rrhcm	581	11	.	.	.
cord-009417-458rrhcm	582	1	The	the	DT
cord-009417-458rrhcm	582	2	delay	delay	NN
cord-009417-458rrhcm	582	3	engendered	engender	VBN
cord-009417-458rrhcm	582	4	by	by	IN
cord-009417-458rrhcm	582	5	working	work	VBG
cord-009417-458rrhcm	582	6	with	with	IN
cord-009417-458rrhcm	582	7	multiple	multiple	JJ
cord-009417-458rrhcm	582	8	or	or	CC
cord-009417-458rrhcm	582	9	unidentifi	unidentifi	JJ
cord-009417-458rrhcm	582	10	ed	ed	NN
cord-009417-458rrhcm	582	11	antibodies	antibody	NNS
cord-009417-458rrhcm	582	12	may	may	MD
cord-009417-458rrhcm	582	13	be	be	VB
cord-009417-458rrhcm	582	14	unacceptable	unacceptable	JJ
cord-009417-458rrhcm	582	15	in	in	IN
cord-009417-458rrhcm	582	16	some	some	DT
cord-009417-458rrhcm	582	17	critical	critical	JJ
cord-009417-458rrhcm	582	18	care	care	NN
cord-009417-458rrhcm	582	19	situations	situation	NNS
cord-009417-458rrhcm	582	20	in	in	IN
cord-009417-458rrhcm	582	21	which	which	WDT
cord-009417-458rrhcm	582	22	the	the	DT
cord-009417-458rrhcm	582	23	need	need	NN
cord-009417-458rrhcm	582	24	for	for	IN
cord-009417-458rrhcm	582	25	oxygen	oxygen	NN
cord-009417-458rrhcm	582	26	-	-	HYPH
cord-009417-458rrhcm	582	27	carrying	carry	VBG
cord-009417-458rrhcm	582	28	capacity	capacity	NN
cord-009417-458rrhcm	582	29	leaves	leave	VBZ
cord-009417-458rrhcm	582	30	no	no	DT
cord-009417-458rrhcm	582	31	choice	choice	NN
cord-009417-458rrhcm	582	32	but	but	IN
cord-009417-458rrhcm	582	33	to	to	TO
cord-009417-458rrhcm	582	34	transfuse	transfuse	VB
cord-009417-458rrhcm	582	35	incompatible	incompatible	JJ
cord-009417-458rrhcm	582	36	blood	blood	NN
cord-009417-458rrhcm	582	37	.	.	.
cord-009417-458rrhcm	583	1	The	the	DT
cord-009417-458rrhcm	583	2	behavior	behavior	NN
cord-009417-458rrhcm	583	3	of	of	IN
cord-009417-458rrhcm	583	4	these	these	DT
cord-009417-458rrhcm	583	5	antibodies	antibody	NNS
cord-009417-458rrhcm	583	6	in	in	IN
cord-009417-458rrhcm	583	7	the	the	DT
cord-009417-458rrhcm	583	8	laboratory	laboratory	NN
cord-009417-458rrhcm	583	9	may	may	MD
cord-009417-458rrhcm	583	10	assist	assist	VB
cord-009417-458rrhcm	583	11	in	in	IN
cord-009417-458rrhcm	583	12	predicting	predict	VBG
cord-009417-458rrhcm	583	13	the	the	DT
cord-009417-458rrhcm	583	14	clinical	clinical	JJ
cord-009417-458rrhcm	583	15	outcome	outcome	NN
cord-009417-458rrhcm	583	16	of	of	IN
cord-009417-458rrhcm	583	17	the	the	DT
cord-009417-458rrhcm	583	18	incompatible	incompatible	JJ
cord-009417-458rrhcm	583	19	transfusion	transfusion	NN
cord-009417-458rrhcm	583	20	.	.	.
cord-009417-458rrhcm	584	1	128	128	CD
cord-009417-458rrhcm	584	2	Special	special	JJ
cord-009417-458rrhcm	584	3	procedures	procedure	NNS
cord-009417-458rrhcm	584	4	such	such	JJ
cord-009417-458rrhcm	584	5	as	as	IN
cord-009417-458rrhcm	584	6	clearance	clearance	NN
cord-009417-458rrhcm	584	7	studies	study	NNS
cord-009417-458rrhcm	584	8	,	,	,
cord-009417-458rrhcm	584	9	129	129	CD
cord-009417-458rrhcm	584	10	fl	fl	NNP
cord-009417-458rrhcm	584	11	ow	ow	NN
cord-009417-458rrhcm	584	12	cytometry	cytometry	NN
cord-009417-458rrhcm	584	13	130	130	CD
cord-009417-458rrhcm	584	14	and	and	CC
cord-009417-458rrhcm	584	15	in	in	IN
cord-009417-458rrhcm	584	16	vivo	vivo	NNP
cord-009417-458rrhcm	584	17	crossmatching	crossmatching	NNP
cord-009417-458rrhcm	584	18	(	(	-LRB-
cord-009417-458rrhcm	584	19	cautious	cautious	JJ
cord-009417-458rrhcm	584	20	administration	administration	NN
cord-009417-458rrhcm	584	21	of	of	IN
cord-009417-458rrhcm	584	22	a	a	DT
cord-009417-458rrhcm	584	23	small	small	JJ
cord-009417-458rrhcm	584	24	aliquot	aliquot	NN
cord-009417-458rrhcm	584	25	of	of	IN
cord-009417-458rrhcm	584	26	blood	blood	NN
cord-009417-458rrhcm	584	27	,	,	,
cord-009417-458rrhcm	584	28	with	with	IN
cord-009417-458rrhcm	584	29	subsequent	subsequent	JJ
cord-009417-458rrhcm	584	30	observation	observation	NN
cord-009417-458rrhcm	584	31	of	of	IN
cord-009417-458rrhcm	584	32	serum	serum	NN
cord-009417-458rrhcm	584	33	and	and	CC
cord-009417-458rrhcm	584	34	urine	urine	NN
cord-009417-458rrhcm	584	35	for	for	IN
cord-009417-458rrhcm	584	36	evidence	evidence	NN
cord-009417-458rrhcm	584	37	of	of	IN
cord-009417-458rrhcm	584	38	hemolysis	hemolysis	NN
cord-009417-458rrhcm	584	39	)	)	-RRB-
cord-009417-458rrhcm	584	40	are	be	VBP
cord-009417-458rrhcm	584	41	useful	useful	JJ
cord-009417-458rrhcm	584	42	if	if	IN
cord-009417-458rrhcm	584	43	time	time	NN
cord-009417-458rrhcm	584	44	permits	permit	VBZ
cord-009417-458rrhcm	584	45	.	.	.
cord-009417-458rrhcm	585	1	Emergency	emergency	NN
cord-009417-458rrhcm	585	2	transfusion	transfusion	NN
cord-009417-458rrhcm	585	3	of	of	IN
cord-009417-458rrhcm	585	4	type	type	NN
cord-009417-458rrhcm	585	5	O	o	NN
cord-009417-458rrhcm	586	1	,	,	,
cord-009417-458rrhcm	586	2	Rh	Rh	NNP
cord-009417-458rrhcm	586	3	-	-	HYPH
cord-009417-458rrhcm	586	4	negative	negative	JJ
cord-009417-458rrhcm	586	5	uncrossmatched	uncrossmatched	JJ
cord-009417-458rrhcm	586	6	blood	blood	NN
cord-009417-458rrhcm	586	7	is	be	VBZ
cord-009417-458rrhcm	586	8	generally	generally	RB
cord-009417-458rrhcm	586	9	reserved	reserve	VBN
cord-009417-458rrhcm	586	10	for	for	IN
cord-009417-458rrhcm	586	11	the	the	DT
cord-009417-458rrhcm	586	12	resuscitation	resuscitation	NN
cord-009417-458rrhcm	586	13	of	of	IN
cord-009417-458rrhcm	586	14	trauma	trauma	NN
cord-009417-458rrhcm	586	15	patients	patient	NNS
cord-009417-458rrhcm	586	16	,	,	,
cord-009417-458rrhcm	586	17	for	for	IN
cord-009417-458rrhcm	586	18	whom	whom	WP
cord-009417-458rrhcm	586	19	the	the	DT
cord-009417-458rrhcm	586	20	delay	delay	NN
cord-009417-458rrhcm	586	21	in	in	IN
cord-009417-458rrhcm	586	22	crossmatching	crossmatching	NN
cord-009417-458rrhcm	586	23	may	may	MD
cord-009417-458rrhcm	586	24	be	be	VB
cord-009417-458rrhcm	586	25	life	life	NN
cord-009417-458rrhcm	586	26	-	-	HYPH
cord-009417-458rrhcm	586	27	threatening	threaten	VBG
cord-009417-458rrhcm	586	28	.	.	.
cord-009417-458rrhcm	587	1	The	the	DT
cord-009417-458rrhcm	587	2	risks	risk	NNS
cord-009417-458rrhcm	587	3	of	of	IN
cord-009417-458rrhcm	587	4	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	587	5	are	be	VBP
cord-009417-458rrhcm	587	6	generally	generally	RB
cord-009417-458rrhcm	587	7	accepted	accept	VBN
cord-009417-458rrhcm	587	8	as	as	IN
cord-009417-458rrhcm	587	9	low	low	JJ
cord-009417-458rrhcm	587	10	.	.	.
cord-009417-458rrhcm	588	1	Even	even	RB
cord-009417-458rrhcm	588	2	Rh	Rh	NNP
cord-009417-458rrhcm	588	3	-	-	HYPH
cord-009417-458rrhcm	588	4	positive	positive	JJ
cord-009417-458rrhcm	588	5	type	type	NN
cord-009417-458rrhcm	588	6	O	o	NN
cord-009417-458rrhcm	588	7	RBCs	rbc	NNS
cord-009417-458rrhcm	588	8	may	may	MD
cord-009417-458rrhcm	588	9	be	be	VB
cord-009417-458rrhcm	588	10	used	use	VBN
cord-009417-458rrhcm	588	11	because	because	IN
cord-009417-458rrhcm	588	12	rates	rate	NNS
cord-009417-458rrhcm	588	13	of	of	IN
cord-009417-458rrhcm	588	14	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	588	15	to	to	IN
cord-009417-458rrhcm	588	16	Rh	Rh	NNP
cord-009417-458rrhcm	588	17	0	0	CD
cord-009417-458rrhcm	588	18	(	(	-LRB-
cord-009417-458rrhcm	588	19	D	D	NNP
cord-009417-458rrhcm	588	20	)	)	-RRB-
cord-009417-458rrhcm	588	21	are	be	VBP
cord-009417-458rrhcm	588	22	low	low	JJ
cord-009417-458rrhcm	588	23	under	under	IN
cord-009417-458rrhcm	588	24	the	the	DT
cord-009417-458rrhcm	588	25	circumstances	circumstance	NNS
cord-009417-458rrhcm	588	26	of	of	IN
cord-009417-458rrhcm	588	27	emergency	emergency	NN
cord-009417-458rrhcm	588	28	transfusion	transfusion	NN
cord-009417-458rrhcm	588	29	.	.	.
cord-009417-458rrhcm	589	1	128	128	CD
cord-009417-458rrhcm	589	2	,	,	,
cord-009417-458rrhcm	589	3	131	131	CD
cord-009417-458rrhcm	589	4	 	 	_SP
cord-009417-458rrhcm	589	5	DIC	DIC	NNP
cord-009417-458rrhcm	589	6	can	can	MD
cord-009417-458rrhcm	589	7	present	present	VB
cord-009417-458rrhcm	589	8	the	the	DT
cord-009417-458rrhcm	589	9	clinician	clinician	NN
cord-009417-458rrhcm	589	10	with	with	IN
cord-009417-458rrhcm	589	11	diffi	diffi	NNP
cord-009417-458rrhcm	589	12	cult	cult	NN
cord-009417-458rrhcm	589	13	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	589	14	choices	choice	NNS
cord-009417-458rrhcm	589	15	.	.	.
cord-009417-458rrhcm	590	1	This	this	DT
cord-009417-458rrhcm	590	2	common	common	JJ
cord-009417-458rrhcm	590	3	disorder	disorder	NN
cord-009417-458rrhcm	590	4	in	in	IN
cord-009417-458rrhcm	590	5	critically	critically	RB
cord-009417-458rrhcm	590	6	ill	ill	JJ
cord-009417-458rrhcm	590	7	patients	patient	NNS
cord-009417-458rrhcm	590	8	may	may	MD
cord-009417-458rrhcm	590	9	be	be	VB
cord-009417-458rrhcm	590	10	manifested	manifest	VBN
cord-009417-458rrhcm	590	11	as	as	IN
cord-009417-458rrhcm	590	12	severe	severe	JJ
cord-009417-458rrhcm	590	13	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	590	14	or	or	CC
cord-009417-458rrhcm	590	15	thrombosis	thrombosis	NN
cord-009417-458rrhcm	590	16	.	.	.
cord-009417-458rrhcm	591	1	Therapy	therapy	NN
cord-009417-458rrhcm	591	2	is	be	VBZ
cord-009417-458rrhcm	591	3	primarily	primarily	RB
cord-009417-458rrhcm	591	4	directed	direct	VBN
cord-009417-458rrhcm	591	5	at	at	IN
cord-009417-458rrhcm	591	6	alleviating	alleviate	VBG
cord-009417-458rrhcm	591	7	the	the	DT
cord-009417-458rrhcm	591	8	cause	cause	NN
cord-009417-458rrhcm	591	9	and	and	CC
cord-009417-458rrhcm	591	10	supporting	support	VBG
cord-009417-458rrhcm	591	11	the	the	DT
cord-009417-458rrhcm	591	12	patient	patient	NN
cord-009417-458rrhcm	591	13	.	.	.
cord-009417-458rrhcm	592	1	Supportive	supportive	JJ
cord-009417-458rrhcm	592	2	therapy	therapy	NN
cord-009417-458rrhcm	592	3	includes	include	VBZ
cord-009417-458rrhcm	592	4	the	the	DT
cord-009417-458rrhcm	592	5	transfusion	transfusion	NN
cord-009417-458rrhcm	592	6	of	of	IN
cord-009417-458rrhcm	592	7	components	component	NNS
cord-009417-458rrhcm	592	8	needed	need	VBN
cord-009417-458rrhcm	592	9	to	to	TO
cord-009417-458rrhcm	592	10	correct	correct	VB
cord-009417-458rrhcm	592	11	the	the	DT
cord-009417-458rrhcm	592	12	bleeding	bleed	VBG
cord-009417-458rrhcm	592	13	diathesis	diathesis	NN
cord-009417-458rrhcm	592	14	caused	cause	VBN
cord-009417-458rrhcm	592	15	by	by	IN
cord-009417-458rrhcm	592	16	the	the	DT
cord-009417-458rrhcm	592	17	consumption	consumption	NN
cord-009417-458rrhcm	592	18	of	of	IN
cord-009417-458rrhcm	592	19	platelets	platelet	NNS
cord-009417-458rrhcm	592	20	and	and	CC
cord-009417-458rrhcm	592	21	fi	fi	NNP
cord-009417-458rrhcm	592	22	brinogen	brinogen	NNP
cord-009417-458rrhcm	592	23	,	,	,
cord-009417-458rrhcm	592	24	in	in	IN
cord-009417-458rrhcm	592	25	addition	addition	NN
cord-009417-458rrhcm	592	26	to	to	IN
cord-009417-458rrhcm	592	27	PRBCs	prbc	NNS
cord-009417-458rrhcm	592	28	to	to	TO
cord-009417-458rrhcm	592	29	restore	restore	VB
cord-009417-458rrhcm	592	30	oxygencarrying	oxygencarrying	NN
cord-009417-458rrhcm	592	31	capacity	capacity	NN
cord-009417-458rrhcm	592	32	.	.	.
cord-009417-458rrhcm	593	1	Platelets	platelet	NNS
cord-009417-458rrhcm	593	2	and	and	CC
cord-009417-458rrhcm	593	3	fi	fi	NNP
cord-009417-458rrhcm	593	4	brinogen	brinogen	NNP
cord-009417-458rrhcm	593	5	(	(	-LRB-
cord-009417-458rrhcm	593	6	as	as	IN
cord-009417-458rrhcm	593	7	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	593	8	)	)	-RRB-
cord-009417-458rrhcm	593	9	are	be	VBP
cord-009417-458rrhcm	593	10	the	the	DT
cord-009417-458rrhcm	593	11	most	most	RBS
cord-009417-458rrhcm	593	12	useful	useful	JJ
cord-009417-458rrhcm	593	13	components	component	NNS
cord-009417-458rrhcm	593	14	needed	need	VBN
cord-009417-458rrhcm	593	15	to	to	TO
cord-009417-458rrhcm	593	16	repair	repair	VB
cord-009417-458rrhcm	593	17	the	the	DT
cord-009417-458rrhcm	593	18	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	593	19	,	,	,
cord-009417-458rrhcm	593	20	but	but	CC
cord-009417-458rrhcm	593	21	their	-PRON-	PRP$
cord-009417-458rrhcm	593	22	use	use	NN
cord-009417-458rrhcm	593	23	risks	risk	NNS
cord-009417-458rrhcm	593	24	merely	merely	RB
cord-009417-458rrhcm	593	25	"	"	``
cord-009417-458rrhcm	593	26	fueling	fuel	VBG
cord-009417-458rrhcm	593	27	the	the	DT
cord-009417-458rrhcm	593	28	fi	fi	NN
cord-009417-458rrhcm	593	29	re	re	NN
cord-009417-458rrhcm	593	30	"	"	''
cord-009417-458rrhcm	593	31	and	and	CC
cord-009417-458rrhcm	593	32	increasing	increase	VBG
cord-009417-458rrhcm	593	33	the	the	DT
cord-009417-458rrhcm	593	34	microthrombosis	microthrombosis	NN
cord-009417-458rrhcm	593	35	of	of	IN
cord-009417-458rrhcm	593	36	DIC	DIC	NNP
cord-009417-458rrhcm	593	37	.	.	.
cord-009417-458rrhcm	594	1	Heparin	heparin	JJ
cord-009417-458rrhcm	594	2	anticoagulation	anticoagulation	NN
cord-009417-458rrhcm	594	3	is	be	VBZ
cord-009417-458rrhcm	594	4	controversial	controversial	JJ
cord-009417-458rrhcm	594	5	132	132	CD
cord-009417-458rrhcm	594	6	,	,	,
cord-009417-458rrhcm	594	7	133	133	CD
cord-009417-458rrhcm	594	8	and	and	CC
cord-009417-458rrhcm	594	9	may	may	MD
cord-009417-458rrhcm	594	10	increase	increase	VB
cord-009417-458rrhcm	594	11	the	the	DT
cord-009417-458rrhcm	594	12	risk	risk	NN
cord-009417-458rrhcm	594	13	of	of	IN
cord-009417-458rrhcm	594	14	bleeding	bleed	VBG
cord-009417-458rrhcm	594	15	,	,	,
cord-009417-458rrhcm	594	16	especially	especially	RB
cord-009417-458rrhcm	594	17	if	if	IN
cord-009417-458rrhcm	594	18	depleted	deplete	VBN
cord-009417-458rrhcm	594	19	factors	factor	NNS
cord-009417-458rrhcm	594	20	are	be	VBP
cord-009417-458rrhcm	594	21	not	not	RB
cord-009417-458rrhcm	594	22	replenished	replenish	VBN
cord-009417-458rrhcm	594	23	.	.	.
cord-009417-458rrhcm	595	1	No	no	DT
cord-009417-458rrhcm	595	2	defi	defi	FW
cord-009417-458rrhcm	595	3	nitive	nitive	JJ
cord-009417-458rrhcm	595	4	clinical	clinical	JJ
cord-009417-458rrhcm	595	5	trials	trial	NNS
cord-009417-458rrhcm	595	6	have	have	VBP
cord-009417-458rrhcm	595	7	endorsed	endorse	VBN
cord-009417-458rrhcm	595	8	the	the	DT
cord-009417-458rrhcm	595	9	routine	routine	JJ
cord-009417-458rrhcm	595	10	use	use	NN
cord-009417-458rrhcm	595	11	of	of	IN
cord-009417-458rrhcm	595	12	heparin	heparin	NN
cord-009417-458rrhcm	595	13	,	,	,
cord-009417-458rrhcm	595	14	and	and	CC
cord-009417-458rrhcm	595	15	randomized	randomized	JJ
cord-009417-458rrhcm	595	16	trials	trial	NNS
cord-009417-458rrhcm	595	17	of	of	IN
cord-009417-458rrhcm	595	18	other	other	JJ
cord-009417-458rrhcm	595	19	components	component	NNS
cord-009417-458rrhcm	595	20	and	and	CC
cord-009417-458rrhcm	595	21	coagulation	coagulation	NN
cord-009417-458rrhcm	595	22	inhibitors	inhibitor	NNS
cord-009417-458rrhcm	595	23	have	have	VBP
cord-009417-458rrhcm	595	24	uniformly	uniformly	RB
cord-009417-458rrhcm	595	25	been	be	VBN
cord-009417-458rrhcm	595	26	negative	negative	JJ
cord-009417-458rrhcm	595	27	.	.	.
cord-009417-458rrhcm	596	1	In	in	IN
cord-009417-458rrhcm	596	2	general	general	JJ
cord-009417-458rrhcm	596	3	,	,	,
cord-009417-458rrhcm	596	4	the	the	DT
cord-009417-458rrhcm	596	5	use	use	NN
cord-009417-458rrhcm	596	6	of	of	IN
cord-009417-458rrhcm	596	7	heparin	heparin	NN
cord-009417-458rrhcm	596	8	and	and	CC
cord-009417-458rrhcm	596	9	antifi	antifi	JJ
cord-009417-458rrhcm	596	10	brinolytic	brinolytic	JJ
cord-009417-458rrhcm	596	11	agents	agent	NNS
cord-009417-458rrhcm	596	12	has	have	VBZ
cord-009417-458rrhcm	596	13	been	be	VBN
cord-009417-458rrhcm	596	14	confi	confi	VBN
cord-009417-458rrhcm	596	15	ned	ned	NNP
cord-009417-458rrhcm	596	16	to	to	IN
cord-009417-458rrhcm	596	17	the	the	DT
cord-009417-458rrhcm	596	18	most	most	RBS
cord-009417-458rrhcm	596	19	severe	severe	JJ
cord-009417-458rrhcm	596	20	and	and	CC
cord-009417-458rrhcm	596	21	protracted	protracted	JJ
cord-009417-458rrhcm	596	22	cases	case	NNS
cord-009417-458rrhcm	596	23	of	of	IN
cord-009417-458rrhcm	596	24	DIC	DIC	NNP
cord-009417-458rrhcm	596	25	.	.	.
cord-009417-458rrhcm	597	1	134	134	CD
cord-009417-458rrhcm	597	2	Cirrhotic	cirrhotic	JJ
cord-009417-458rrhcm	597	3	patients	patient	NNS
cord-009417-458rrhcm	597	4	or	or	CC
cord-009417-458rrhcm	597	5	those	those	DT
cord-009417-458rrhcm	597	6	with	with	IN
cord-009417-458rrhcm	597	7	fulminant	fulminant	JJ
cord-009417-458rrhcm	597	8	hepatic	hepatic	JJ
cord-009417-458rrhcm	597	9	failure	failure	NN
cord-009417-458rrhcm	597	10	have	have	VBP
cord-009417-458rrhcm	597	11	a	a	DT
cord-009417-458rrhcm	597	12	variety	variety	NN
cord-009417-458rrhcm	597	13	of	of	IN
cord-009417-458rrhcm	597	14	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	597	15	disorders	disorder	NNS
cord-009417-458rrhcm	597	16	that	that	WDT
cord-009417-458rrhcm	597	17	complicate	complicate	VBP
cord-009417-458rrhcm	597	18	transfusion	transfusion	NN
cord-009417-458rrhcm	597	19	management	management	NN
cord-009417-458rrhcm	597	20	of	of	IN
cord-009417-458rrhcm	597	21	a	a	DT
cord-009417-458rrhcm	597	22	bleeding	bleed	VBG
cord-009417-458rrhcm	597	23	patient	patient	NN
cord-009417-458rrhcm	597	24	.	.	.
cord-009417-458rrhcm	598	1	135	135	CD
cord-009417-458rrhcm	598	2	Hepatic	hepatic	JJ
cord-009417-458rrhcm	598	3	synthesis	synthesis	NN
cord-009417-458rrhcm	598	4	of	of	IN
cord-009417-458rrhcm	598	5	coagulation	coagulation	NN
cord-009417-458rrhcm	598	6	factors	factor	NNS
cord-009417-458rrhcm	598	7	may	may	MD
cord-009417-458rrhcm	598	8	be	be	VB
cord-009417-458rrhcm	598	9	markedly	markedly	RB
cord-009417-458rrhcm	598	10	diminished	diminish	VBN
cord-009417-458rrhcm	598	11	,	,	,
cord-009417-458rrhcm	598	12	thereby	thereby	RB
cord-009417-458rrhcm	598	13	necessitating	necessitate	VBG
cord-009417-458rrhcm	598	14	replacement	replacement	NN
cord-009417-458rrhcm	598	15	by	by	IN
cord-009417-458rrhcm	598	16	FFP	FFP	NNP
cord-009417-458rrhcm	598	17	or	or	CC
cord-009417-458rrhcm	598	18	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	598	19	.	.	.
cord-009417-458rrhcm	599	1	Patterns	pattern	NNS
cord-009417-458rrhcm	599	2	of	of	IN
cord-009417-458rrhcm	599	3	factor	factor	NN
cord-009417-458rrhcm	599	4	diminution	diminution	NN
cord-009417-458rrhcm	599	5	may	may	MD
cord-009417-458rrhcm	599	6	vary	vary	VB
cord-009417-458rrhcm	599	7	between	between	IN
cord-009417-458rrhcm	599	8	acute	acute	JJ
cord-009417-458rrhcm	599	9	hepatic	hepatic	JJ
cord-009417-458rrhcm	599	10	necrosis	necrosis	NN
cord-009417-458rrhcm	599	11	and	and	CC
cord-009417-458rrhcm	599	12	chronic	chronic	JJ
cord-009417-458rrhcm	599	13	cirrhosis	cirrhosis	NN
cord-009417-458rrhcm	599	14	.	.	.
cord-009417-458rrhcm	600	1	136	136	CD
cord-009417-458rrhcm	601	1	Associated	associated	JJ
cord-009417-458rrhcm	601	2	hemodynamic	hemodynamic	JJ
cord-009417-458rrhcm	601	3	alterations	alteration	NNS
cord-009417-458rrhcm	601	4	may	may	MD
cord-009417-458rrhcm	601	5	make	make	VB
cord-009417-458rrhcm	601	6	it	-PRON-	PRP
cord-009417-458rrhcm	601	7	impossible	impossible	JJ
cord-009417-458rrhcm	601	8	to	to	TO
cord-009417-458rrhcm	601	9	administer	administer	VB
cord-009417-458rrhcm	601	10	the	the	DT
cord-009417-458rrhcm	601	11	volumes	volume	NNS
cord-009417-458rrhcm	601	12	required	require	VBN
cord-009417-458rrhcm	601	13	for	for	IN
cord-009417-458rrhcm	601	14	effective	effective	JJ
cord-009417-458rrhcm	601	15	hemostasis	hemostasis	NN
cord-009417-458rrhcm	601	16	,	,	,
cord-009417-458rrhcm	601	17	however	however	RB
cord-009417-458rrhcm	601	18	,	,	,
cord-009417-458rrhcm	601	19	and	and	CC
cord-009417-458rrhcm	601	20	any	any	DT
cord-009417-458rrhcm	601	21	effect	effect	NN
cord-009417-458rrhcm	601	22	is	be	VBZ
cord-009417-458rrhcm	601	23	transient	transient	JJ
cord-009417-458rrhcm	601	24	.	.	.
cord-009417-458rrhcm	602	1	The	the	DT
cord-009417-458rrhcm	602	2	use	use	NN
cord-009417-458rrhcm	602	3	of	of	IN
cord-009417-458rrhcm	602	4	factor	factor	NN
cord-009417-458rrhcm	602	5	concentrates	concentrate	VBZ
cord-009417-458rrhcm	602	6	or	or	CC
cord-009417-458rrhcm	602	7	antifi	antifi	NN
cord-009417-458rrhcm	602	8	brinolytic	brinolytic	JJ
cord-009417-458rrhcm	602	9	agents	agent	NNS
cord-009417-458rrhcm	602	10	may	may	MD
cord-009417-458rrhcm	602	11	precipitate	precipitate	VB
cord-009417-458rrhcm	602	12	thrombosis	thrombosis	NN
cord-009417-458rrhcm	602	13	.	.	.
cord-009417-458rrhcm	603	1	Activation	activation	NN
cord-009417-458rrhcm	603	2	of	of	IN
cord-009417-458rrhcm	603	3	fi	fi	NNP
cord-009417-458rrhcm	603	4	brinolysis	brinolysis	NN
cord-009417-458rrhcm	603	5	and	and	CC
cord-009417-458rrhcm	603	6	decreased	decrease	VBD
cord-009417-458rrhcm	603	7	clearance	clearance	NN
cord-009417-458rrhcm	603	8	of	of	IN
cord-009417-458rrhcm	603	9	activated	activate	VBN
cord-009417-458rrhcm	603	10	factors	factor	NNS
cord-009417-458rrhcm	603	11	may	may	MD
cord-009417-458rrhcm	603	12	produce	produce	VB
cord-009417-458rrhcm	603	13	or	or	CC
cord-009417-458rrhcm	603	14	mimic	mimic	VB
cord-009417-458rrhcm	603	15	chronic	chronic	JJ
cord-009417-458rrhcm	603	16	DIC	DIC	NNP
cord-009417-458rrhcm	603	17	,	,	,
cord-009417-458rrhcm	603	18	thus	thus	RB
cord-009417-458rrhcm	603	19	further	further	RB
cord-009417-458rrhcm	603	20	exacerbating	exacerbate	VBG
cord-009417-458rrhcm	603	21	the	the	DT
cord-009417-458rrhcm	603	22	factor	factor	NN
cord-009417-458rrhcm	603	23	defi	defi	NNP
cord-009417-458rrhcm	603	24	ciencies	ciencies	NNP
cord-009417-458rrhcm	603	25	and	and	CC
cord-009417-458rrhcm	603	26	impairing	impair	VBG
cord-009417-458rrhcm	603	27	coagulation	coagulation	NN
cord-009417-458rrhcm	603	28	.	.	.
cord-009417-458rrhcm	604	1	Abnormal	abnormal	JJ
cord-009417-458rrhcm	604	2	platelet	platelet	NN
cord-009417-458rrhcm	604	3	function	function	NN
cord-009417-458rrhcm	604	4	and	and	CC
cord-009417-458rrhcm	604	5	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	604	6	may	may	MD
cord-009417-458rrhcm	604	7	contribute	contribute	VB
cord-009417-458rrhcm	604	8	to	to	IN
cord-009417-458rrhcm	604	9	the	the	DT
cord-009417-458rrhcm	604	10	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	604	11	of	of	IN
cord-009417-458rrhcm	604	12	liver	liver	NN
cord-009417-458rrhcm	604	13	disease	disease	NN
cord-009417-458rrhcm	604	14	,	,	,
cord-009417-458rrhcm	604	15	with	with	IN
cord-009417-458rrhcm	604	16	concomitant	concomitant	JJ
cord-009417-458rrhcm	604	17	splenomegaly	splenomegaly	NN
cord-009417-458rrhcm	604	18	reducing	reduce	VBG
cord-009417-458rrhcm	604	19	the	the	DT
cord-009417-458rrhcm	604	20	effectiveness	effectiveness	NN
cord-009417-458rrhcm	604	21	of	of	IN
cord-009417-458rrhcm	604	22	platelet	platelet	NN
cord-009417-458rrhcm	604	23	transfusions	transfusion	NNS
cord-009417-458rrhcm	604	24	.	.	.
cord-009417-458rrhcm	605	1	Bleeding	bleed	VBG
cord-009417-458rrhcm	605	2	in	in	IN
cord-009417-458rrhcm	605	3	uremic	uremic	JJ
cord-009417-458rrhcm	605	4	patients	patient	NNS
cord-009417-458rrhcm	605	5	is	be	VBZ
cord-009417-458rrhcm	605	6	exacerbated	exacerbate	VBN
cord-009417-458rrhcm	605	7	by	by	IN
cord-009417-458rrhcm	605	8	an	an	DT
cord-009417-458rrhcm	605	9	acquired	acquire	VBN
cord-009417-458rrhcm	605	10	platelet	platelet	NN
cord-009417-458rrhcm	605	11	defect	defect	NN
cord-009417-458rrhcm	605	12	,	,	,
cord-009417-458rrhcm	605	13	in	in	IN
cord-009417-458rrhcm	605	14	part	part	NN
cord-009417-458rrhcm	605	15	secondary	secondary	JJ
cord-009417-458rrhcm	605	16	to	to	IN
cord-009417-458rrhcm	605	17	dialyzable	dialyzable	JJ
cord-009417-458rrhcm	605	18	circulating	circulate	VBG
cord-009417-458rrhcm	605	19	molecules	molecule	NNS
cord-009417-458rrhcm	605	20	soluble	soluble	JJ
cord-009417-458rrhcm	605	21	in	in	IN
cord-009417-458rrhcm	605	22	platelet	platelet	NN
cord-009417-458rrhcm	605	23	membranes	membrane	NNS
cord-009417-458rrhcm	605	24	.	.	.
cord-009417-458rrhcm	606	1	Plateletassociated	Plateletassociated	NNP
cord-009417-458rrhcm	606	2	vWF	vWF	NNP
cord-009417-458rrhcm	606	3	and	and	CC
cord-009417-458rrhcm	606	4	plasma	plasma	NN
cord-009417-458rrhcm	606	5	high	high	JJ
cord-009417-458rrhcm	606	6	-	-	HYPH
cord-009417-458rrhcm	606	7	molecular	molecular	JJ
cord-009417-458rrhcm	606	8	-	-	HYPH
cord-009417-458rrhcm	606	9	weight	weight	NN
cord-009417-458rrhcm	606	10	vWF	vwf	NN
cord-009417-458rrhcm	606	11	multimers	multimer	NNS
cord-009417-458rrhcm	606	12	have	have	VBP
cord-009417-458rrhcm	606	13	also	also	RB
cord-009417-458rrhcm	606	14	been	be	VBN
cord-009417-458rrhcm	606	15	shown	show	VBN
cord-009417-458rrhcm	606	16	to	to	TO
cord-009417-458rrhcm	606	17	be	be	VB
cord-009417-458rrhcm	606	18	decreased	decrease	VBN
cord-009417-458rrhcm	606	19	,	,	,
cord-009417-458rrhcm	606	20	137	137	CD
cord-009417-458rrhcm	606	21	which	which	WDT
cord-009417-458rrhcm	606	22	may	may	MD
cord-009417-458rrhcm	606	23	explain	explain	VB
cord-009417-458rrhcm	606	24	the	the	DT
cord-009417-458rrhcm	606	25	benefi	benefi	NNP
cord-009417-458rrhcm	606	26	t	t	NN
cord-009417-458rrhcm	606	27	shown	show	VBN
cord-009417-458rrhcm	606	28	by	by	IN
cord-009417-458rrhcm	606	29	DDAVP	DDAVP	NNP
cord-009417-458rrhcm	606	30	138	138	CD
cord-009417-458rrhcm	606	31	and	and	CC
cord-009417-458rrhcm	606	32	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	606	33	in	in	IN
cord-009417-458rrhcm	606	34	shortening	shorten	VBG
cord-009417-458rrhcm	606	35	the	the	DT
cord-009417-458rrhcm	606	36	bleeding	bleed	VBG
cord-009417-458rrhcm	606	37	time	time	NN
cord-009417-458rrhcm	606	38	and	and	CC
cord-009417-458rrhcm	606	39	improving	improve	VBG
cord-009417-458rrhcm	606	40	hemostasis	hemostasis	NN
cord-009417-458rrhcm	606	41	in	in	IN
cord-009417-458rrhcm	606	42	some	some	DT
cord-009417-458rrhcm	606	43	uremic	uremic	JJ
cord-009417-458rrhcm	606	44	patients	patient	NNS
cord-009417-458rrhcm	606	45	.	.	.
cord-009417-458rrhcm	607	1	Raising	raise	VBG
cord-009417-458rrhcm	607	2	the	the	DT
cord-009417-458rrhcm	607	3	Hct	Hct	NNP
cord-009417-458rrhcm	607	4	by	by	IN
cord-009417-458rrhcm	607	5	red	red	JJ
cord-009417-458rrhcm	607	6	cell	cell	NN
cord-009417-458rrhcm	607	7	transfusion	transfusion	NN
cord-009417-458rrhcm	607	8	in	in	IN
cord-009417-458rrhcm	607	9	anemic	anemic	JJ
cord-009417-458rrhcm	607	10	patients	patient	NNS
cord-009417-458rrhcm	607	11	has	have	VBZ
cord-009417-458rrhcm	607	12	also	also	RB
cord-009417-458rrhcm	607	13	been	be	VBN
cord-009417-458rrhcm	607	14	shown	show	VBN
cord-009417-458rrhcm	607	15	to	to	TO
cord-009417-458rrhcm	607	16	shorten	shorten	VB
cord-009417-458rrhcm	607	17	the	the	DT
cord-009417-458rrhcm	607	18	bleeding	bleed	VBG
cord-009417-458rrhcm	607	19	time	time	NN
cord-009417-458rrhcm	607	20	,	,	,
cord-009417-458rrhcm	607	21	presumably	presumably	RB
cord-009417-458rrhcm	607	22	as	as	IN
cord-009417-458rrhcm	607	23	a	a	DT
cord-009417-458rrhcm	607	24	result	result	NN
cord-009417-458rrhcm	607	25	of	of	IN
cord-009417-458rrhcm	607	26	blood	blood	NN
cord-009417-458rrhcm	607	27	vessel	vessel	NN
cord-009417-458rrhcm	607	28	wall	wall	NN
cord-009417-458rrhcm	607	29	-	-	HYPH
cord-009417-458rrhcm	607	30	laminar	laminar	JJ
cord-009417-458rrhcm	607	31	blood	blood	NN
cord-009417-458rrhcm	607	32	fl	fl	NNP
cord-009417-458rrhcm	607	33	ow	ow	NNP
cord-009417-458rrhcm	607	34	interaction	interaction	NN
cord-009417-458rrhcm	607	35	.	.	.
cord-009417-458rrhcm	608	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	608	2	of	of	IN
cord-009417-458rrhcm	608	3	platelets	platelet	NNS
cord-009417-458rrhcm	608	4	in	in	IN
cord-009417-458rrhcm	608	5	the	the	DT
cord-009417-458rrhcm	608	6	absence	absence	NN
cord-009417-458rrhcm	608	7	of	of	IN
cord-009417-458rrhcm	608	8	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	608	9	is	be	VBZ
cord-009417-458rrhcm	608	10	unlikely	unlikely	JJ
cord-009417-458rrhcm	608	11	to	to	TO
cord-009417-458rrhcm	608	12	be	be	VB
cord-009417-458rrhcm	608	13	of	of	IN
cord-009417-458rrhcm	608	14	benefi	benefi	NNP
cord-009417-458rrhcm	608	15	t	t	NNP
cord-009417-458rrhcm	608	16	because	because	IN
cord-009417-458rrhcm	608	17	the	the	DT
cord-009417-458rrhcm	608	18	transfused	transfuse	VBN
cord-009417-458rrhcm	608	19	platelets	platelet	NNS
cord-009417-458rrhcm	608	20	rapidly	rapidly	RB
cord-009417-458rrhcm	608	21	become	become	VBP
cord-009417-458rrhcm	608	22	dysfunctional	dysfunctional	JJ
cord-009417-458rrhcm	608	23	.	.	.
cord-009417-458rrhcm	609	1	More	more	RBR
cord-009417-458rrhcm	609	2	aggressive	aggressive	JJ
cord-009417-458rrhcm	609	3	hemodialysis	hemodialysis	NN
cord-009417-458rrhcm	609	4	is	be	VBZ
cord-009417-458rrhcm	609	5	the	the	DT
cord-009417-458rrhcm	609	6	most	most	RBS
cord-009417-458rrhcm	609	7	widely	widely	RB
cord-009417-458rrhcm	609	8	accepted	accept	VBN
cord-009417-458rrhcm	609	9	method	method	NN
cord-009417-458rrhcm	609	10	of	of	IN
cord-009417-458rrhcm	609	11	reducing	reduce	VBG
cord-009417-458rrhcm	609	12	platelet	platelet	NN
cord-009417-458rrhcm	609	13	dysfunction	dysfunction	NN
cord-009417-458rrhcm	609	14	.	.	.
cord-009417-458rrhcm	610	1	BMT	BMT	NNP
cord-009417-458rrhcm	610	2	patients	patient	NNS
cord-009417-458rrhcm	610	3	are	be	VBP
cord-009417-458rrhcm	610	4	vulnerable	vulnerable	JJ
cord-009417-458rrhcm	610	5	to	to	IN
cord-009417-458rrhcm	610	6	the	the	DT
cord-009417-458rrhcm	610	7	severe	severe	JJ
cord-009417-458rrhcm	610	8	infectious	infectious	JJ
cord-009417-458rrhcm	610	9	and	and	CC
cord-009417-458rrhcm	610	10	toxic	toxic	JJ
cord-009417-458rrhcm	610	11	side	side	NN
cord-009417-458rrhcm	610	12	effects	effect	NNS
cord-009417-458rrhcm	610	13	of	of	IN
cord-009417-458rrhcm	610	14	ablative	ablative	JJ
cord-009417-458rrhcm	610	15	treatment	treatment	NN
cord-009417-458rrhcm	610	16	and	and	CC
cord-009417-458rrhcm	610	17	hence	hence	RB
cord-009417-458rrhcm	610	18	may	may	MD
cord-009417-458rrhcm	610	19	be	be	VB
cord-009417-458rrhcm	610	20	cared	care	VBN
cord-009417-458rrhcm	610	21	for	for	IN
cord-009417-458rrhcm	610	22	in	in	IN
cord-009417-458rrhcm	610	23	critical	critical	JJ
cord-009417-458rrhcm	610	24	care	care	NN
cord-009417-458rrhcm	610	25	units	unit	NNS
cord-009417-458rrhcm	610	26	.	.	.
cord-009417-458rrhcm	611	1	These	these	DT
cord-009417-458rrhcm	611	2	patients	patient	NNS
cord-009417-458rrhcm	611	3	may	may	MD
cord-009417-458rrhcm	611	4	have	have	VB
cord-009417-458rrhcm	611	5	intensive	intensive	JJ
cord-009417-458rrhcm	611	6	red	red	JJ
cord-009417-458rrhcm	611	7	cell	cell	NN
cord-009417-458rrhcm	611	8	and	and	CC
cord-009417-458rrhcm	611	9	platelet	platelet	NN
cord-009417-458rrhcm	611	10	transfusion	transfusion	NN
cord-009417-458rrhcm	611	11	requirements	requirement	NNS
cord-009417-458rrhcm	611	12	and	and	CC
cord-009417-458rrhcm	611	13	need	need	VB
cord-009417-458rrhcm	611	14	specialized	specialized	JJ
cord-009417-458rrhcm	611	15	products	product	NNS
cord-009417-458rrhcm	611	16	such	such	JJ
cord-009417-458rrhcm	611	17	as	as	IN
cord-009417-458rrhcm	611	18	CMV	CMV	NNP
cord-009417-458rrhcm	611	19	-	-	HYPH
cord-009417-458rrhcm	611	20	negative	negative	JJ
cord-009417-458rrhcm	611	21	and	and	CC
cord-009417-458rrhcm	611	22	irradiated	irradiated	JJ
cord-009417-458rrhcm	611	23	blood	blood	NN
cord-009417-458rrhcm	611	24	components	component	NNS
cord-009417-458rrhcm	611	25	.	.	.
cord-009417-458rrhcm	612	1	A	a	DT
cord-009417-458rrhcm	612	2	blood	blood	NN
cord-009417-458rrhcm	612	3	bank	bank	NN
cord-009417-458rrhcm	612	4	problem	problem	NN
cord-009417-458rrhcm	612	5	uniquely	uniquely	RB
cord-009417-458rrhcm	612	6	encountered	encounter	VBN
cord-009417-458rrhcm	612	7	in	in	IN
cord-009417-458rrhcm	612	8	BMT	BMT	NNP
cord-009417-458rrhcm	612	9	is	be	VBZ
cord-009417-458rrhcm	612	10	the	the	DT
cord-009417-458rrhcm	612	11	need	need	NN
cord-009417-458rrhcm	612	12	to	to	TO
cord-009417-458rrhcm	612	13	switch	switch	VB
cord-009417-458rrhcm	612	14	the	the	DT
cord-009417-458rrhcm	612	15	patient	patient	NN
cord-009417-458rrhcm	612	16	's	's	POS
cord-009417-458rrhcm	612	17	ABO	ABO	NNP
cord-009417-458rrhcm	612	18	group	group	NN
cord-009417-458rrhcm	612	19	because	because	IN
cord-009417-458rrhcm	612	20	of	of	IN
cord-009417-458rrhcm	612	21	an	an	DT
cord-009417-458rrhcm	612	22	ABO	ABO	NNP
cord-009417-458rrhcm	612	23	-	-	HYPH
cord-009417-458rrhcm	612	24	mismatched	mismatch	VBN
cord-009417-458rrhcm	612	25	transplant	transplant	NN
cord-009417-458rrhcm	612	26	,	,	,
cord-009417-458rrhcm	612	27	thus	thus	RB
cord-009417-458rrhcm	612	28	necessitating	necessitate	VBG
cord-009417-458rrhcm	612	29	an	an	DT
cord-009417-458rrhcm	612	30	exchange	exchange	NN
cord-009417-458rrhcm	612	31	transfusion	transfusion	NN
cord-009417-458rrhcm	612	32	of	of	IN
cord-009417-458rrhcm	612	33	red	red	JJ
cord-009417-458rrhcm	612	34	cells	cell	NNS
cord-009417-458rrhcm	612	35	and	and	CC
cord-009417-458rrhcm	612	36	plasma	plasma	NN
cord-009417-458rrhcm	612	37	-	-	HYPH
cord-009417-458rrhcm	612	38	containing	contain	VBG
cord-009417-458rrhcm	612	39	products	product	NNS
cord-009417-458rrhcm	612	40	(	(	-LRB-
cord-009417-458rrhcm	612	41	i.e.	i.e.	FW
cord-009417-458rrhcm	612	42	,	,	,
cord-009417-458rrhcm	612	43	platelet	platelet	NN
cord-009417-458rrhcm	612	44	concentrates	concentrate	NNS
cord-009417-458rrhcm	612	45	)	)	-RRB-
cord-009417-458rrhcm	612	46	of	of	IN
cord-009417-458rrhcm	612	47	differing	differ	VBG
cord-009417-458rrhcm	612	48	ABO	ABO	NNP
cord-009417-458rrhcm	612	49	type	type	NN
cord-009417-458rrhcm	612	50	to	to	TO
cord-009417-458rrhcm	612	51	avoid	avoid	VB
cord-009417-458rrhcm	612	52	hemolysis	hemolysis	NN
cord-009417-458rrhcm	612	53	of	of	IN
cord-009417-458rrhcm	612	54	donor	donor	NN
cord-009417-458rrhcm	612	55	and	and	CC
cord-009417-458rrhcm	612	56	recipient	recipient	NN
cord-009417-458rrhcm	612	57	cells	cell	NNS
cord-009417-458rrhcm	612	58	.	.	.
cord-009417-458rrhcm	613	1	BMT	BMT	NNP
cord-009417-458rrhcm	613	2	patients	patient	NNS
cord-009417-458rrhcm	613	3	may	may	MD
cord-009417-458rrhcm	613	4	also	also	RB
cord-009417-458rrhcm	613	5	manifest	manifest	VB
cord-009417-458rrhcm	613	6	an	an	DT
cord-009417-458rrhcm	613	7	increased	increase	VBN
cord-009417-458rrhcm	613	8	rate	rate	NN
cord-009417-458rrhcm	613	9	of	of	IN
cord-009417-458rrhcm	613	10	delayed	delayed	JJ
cord-009417-458rrhcm	613	11	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	613	12	reactions	reaction	NNS
cord-009417-458rrhcm	613	13	139	139	CD
cord-009417-458rrhcm	613	14	as	as	IN
cord-009417-458rrhcm	613	15	donor	donor	NN
cord-009417-458rrhcm	613	16	"	"	``
cord-009417-458rrhcm	613	17	passenger	passenger	NN
cord-009417-458rrhcm	613	18	"	"	''
cord-009417-458rrhcm	613	19	lymphocytes	lymphocyte	NNS
cord-009417-458rrhcm	613	20	recognize	recognize	VBP
cord-009417-458rrhcm	613	21	recipient	recipient	NN
cord-009417-458rrhcm	613	22	or	or	CC
cord-009417-458rrhcm	613	23	transfused	transfuse	VBN
cord-009417-458rrhcm	613	24	red	red	JJ
cord-009417-458rrhcm	613	25	cell	cell	NN
cord-009417-458rrhcm	613	26	antigens	antigen	NNS
cord-009417-458rrhcm	613	27	.	.	.
cord-009417-458rrhcm	614	1	Patients	patient	NNS
cord-009417-458rrhcm	614	2	should	should	MD
cord-009417-458rrhcm	614	3	be	be	VB
cord-009417-458rrhcm	614	4	monitored	monitor	VBN
cord-009417-458rrhcm	614	5	particularly	particularly	RB
cord-009417-458rrhcm	614	6	closely	closely	RB
cord-009417-458rrhcm	614	7	between	between	IN
cord-009417-458rrhcm	614	8	days	day	NNS
cord-009417-458rrhcm	614	9	10	10	CD
cord-009417-458rrhcm	614	10	and	and	CC
cord-009417-458rrhcm	614	11	20	20	CD
cord-009417-458rrhcm	614	12	after	after	IN
cord-009417-458rrhcm	614	13	a	a	DT
cord-009417-458rrhcm	614	14	minormismatched	minormismatche	VBN
cord-009417-458rrhcm	614	15	allogeneic	allogeneic	NN
cord-009417-458rrhcm	614	16	transplant	transplant	NN
cord-009417-458rrhcm	614	17	,	,	,
cord-009417-458rrhcm	614	18	and	and	CC
cord-009417-458rrhcm	614	19	aggressive	aggressive	JJ
cord-009417-458rrhcm	614	20	transfusion	transfusion	NN
cord-009417-458rrhcm	614	21	should	should	MD
cord-009417-458rrhcm	614	22	be	be	VB
cord-009417-458rrhcm	614	23	undertaken	undertake	VBN
cord-009417-458rrhcm	614	24	if	if	IN
cord-009417-458rrhcm	614	25	the	the	DT
cord-009417-458rrhcm	614	26	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	614	27	level	level	NN
cord-009417-458rrhcm	614	28	falls	fall	VBZ
cord-009417-458rrhcm	614	29	and	and	CC
cord-009417-458rrhcm	614	30	the	the	DT
cord-009417-458rrhcm	614	31	DAT	DAT	NNP
cord-009417-458rrhcm	614	32	result	result	NN
cord-009417-458rrhcm	614	33	becomes	become	VBZ
cord-009417-458rrhcm	614	34	positive	positive	JJ
cord-009417-458rrhcm	614	35	.	.	.
cord-009417-458rrhcm	615	1	The	the	DT
cord-009417-458rrhcm	615	2	safest	safe	JJS
cord-009417-458rrhcm	615	3	transfusion	transfusion	NN
cord-009417-458rrhcm	615	4	is	be	VBZ
cord-009417-458rrhcm	615	5	one	one	NN
cord-009417-458rrhcm	615	6	that	that	WDT
cord-009417-458rrhcm	615	7	is	be	VBZ
cord-009417-458rrhcm	615	8	not	not	RB
cord-009417-458rrhcm	615	9	given	give	VBN
cord-009417-458rrhcm	615	10	.	.	.
cord-009417-458rrhcm	616	1	Therefore	therefore	RB
cord-009417-458rrhcm	616	2	,	,	,
cord-009417-458rrhcm	616	3	alternatives	alternative	NNS
cord-009417-458rrhcm	616	4	to	to	IN
cord-009417-458rrhcm	616	5	blood	blood	NN
cord-009417-458rrhcm	616	6	component	component	NN
cord-009417-458rrhcm	616	7	therapy	therapy	NN
cord-009417-458rrhcm	616	8	continue	continue	VBP
cord-009417-458rrhcm	616	9	to	to	TO
cord-009417-458rrhcm	616	10	be	be	VB
cord-009417-458rrhcm	616	11	sought	seek	VBN
cord-009417-458rrhcm	616	12	and	and	CC
cord-009417-458rrhcm	616	13	are	be	VBP
cord-009417-458rrhcm	616	14	valuable	valuable	JJ
cord-009417-458rrhcm	616	15	adjuncts	adjunct	NNS
cord-009417-458rrhcm	616	16	in	in	IN
cord-009417-458rrhcm	616	17	some	some	DT
cord-009417-458rrhcm	616	18	instances	instance	NNS
cord-009417-458rrhcm	616	19	.	.	.
cord-009417-458rrhcm	617	1	It	-PRON-	PRP
cord-009417-458rrhcm	617	2	is	be	VBZ
cord-009417-458rrhcm	617	3	possible	possible	JJ
cord-009417-458rrhcm	617	4	to	to	TO
cord-009417-458rrhcm	617	5	limit	limit	VB
cord-009417-458rrhcm	617	6	homologous	homologous	JJ
cord-009417-458rrhcm	617	7	blood	blood	NN
cord-009417-458rrhcm	617	8	exposure	exposure	NN
cord-009417-458rrhcm	617	9	by	by	IN
cord-009417-458rrhcm	617	10	the	the	DT
cord-009417-458rrhcm	617	11	appropriate	appropriate	JJ
cord-009417-458rrhcm	617	12	use	use	NN
cord-009417-458rrhcm	617	13	of	of	IN
cord-009417-458rrhcm	617	14	pharmacologic	pharmacologic	JJ
cord-009417-458rrhcm	617	15	agents	agent	NNS
cord-009417-458rrhcm	617	16	that	that	WDT
cord-009417-458rrhcm	617	17	promote	promote	VBP
cord-009417-458rrhcm	617	18	hemostasis	hemostasis	NN
cord-009417-458rrhcm	617	19	and	and	CC
cord-009417-458rrhcm	617	20	the	the	DT
cord-009417-458rrhcm	617	21	administration	administration	NN
cord-009417-458rrhcm	617	22	of	of	IN
cord-009417-458rrhcm	617	23	recombinant	recombinant	JJ
cord-009417-458rrhcm	617	24	hematopoietic	hematopoietic	JJ
cord-009417-458rrhcm	617	25	growth	growth	NN
cord-009417-458rrhcm	617	26	factors	factor	NNS
cord-009417-458rrhcm	617	27	or	or	CC
cord-009417-458rrhcm	617	28	biologic	biologic	JJ
cord-009417-458rrhcm	617	29	growth	growth	NN
cord-009417-458rrhcm	618	1	modifi	modifi	NNP
cord-009417-458rrhcm	618	2	ers	er	NNS
cord-009417-458rrhcm	618	3	to	to	TO
cord-009417-458rrhcm	618	4	stimulate	stimulate	VB
cord-009417-458rrhcm	618	5	marrow	marrow	NN
cord-009417-458rrhcm	618	6	hematopoiesis	hematopoiesis	NN
cord-009417-458rrhcm	618	7	.	.	.
cord-009417-458rrhcm	619	1	Only	only	RB
cord-009417-458rrhcm	619	2	one	one	CD
cord-009417-458rrhcm	619	3	substitute	substitute	NN
cord-009417-458rrhcm	619	4	for	for	IN
cord-009417-458rrhcm	619	5	RBC	RBC	NNP
cord-009417-458rrhcm	619	6	transfusions	transfusion	NNS
cord-009417-458rrhcm	619	7	has	have	VBZ
cord-009417-458rrhcm	619	8	been	be	VBN
cord-009417-458rrhcm	619	9	approved	approve	VBN
cord-009417-458rrhcm	619	10	in	in	IN
cord-009417-458rrhcm	619	11	the	the	DT
cord-009417-458rrhcm	619	12	United	United	NNP
cord-009417-458rrhcm	619	13	States	States	NNP
cord-009417-458rrhcm	619	14	,	,	,
cord-009417-458rrhcm	619	15	a	a	DT
cord-009417-458rrhcm	619	16	polyfl	polyfl	NNP
cord-009417-458rrhcm	619	17	uorocarbon	uorocarbon	NNP
cord-009417-458rrhcm	619	18	oxygen	oxygen	NN
cord-009417-458rrhcm	619	19	carrier	carrier	NN
cord-009417-458rrhcm	619	20	with	with	IN
cord-009417-458rrhcm	619	21	signifi	signifi	NNP
cord-009417-458rrhcm	619	22	ca	can	MD
cord-009417-458rrhcm	619	23	nt	not	RB
cord-009417-458rrhcm	619	24	limitations	limitation	NNS
cord-009417-458rrhcm	619	25	as	as	IN
cord-009417-458rrhcm	619	26	a	a	DT
cord-009417-458rrhcm	619	27	blood	blood	NN
cord-009417-458rrhcm	619	28	substitute	substitute	NN
cord-009417-458rrhcm	619	29	.	.	.
cord-009417-458rrhcm	620	1	140	140	CD
cord-009417-458rrhcm	620	2	Other	other	JJ
cord-009417-458rrhcm	620	3	preparations	preparation	NNS
cord-009417-458rrhcm	620	4	that	that	WDT
cord-009417-458rrhcm	620	5	have	have	VBP
cord-009417-458rrhcm	620	6	been	be	VBN
cord-009417-458rrhcm	620	7	explored	explore	VBN
cord-009417-458rrhcm	620	8	in	in	IN
cord-009417-458rrhcm	620	9	clinical	clinical	JJ
cord-009417-458rrhcm	620	10	trials	trial	NNS
cord-009417-458rrhcm	620	11	are	be	VBP
cord-009417-458rrhcm	620	12	cell	cell	NN
cord-009417-458rrhcm	620	13	-	-	HYPH
cord-009417-458rrhcm	620	14	free	free	JJ
cord-009417-458rrhcm	620	15	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	620	16	solutions	solution	NNS
cord-009417-458rrhcm	620	17	cross	cross	NN
cord-009417-458rrhcm	620	18	-	-	JJ
cord-009417-458rrhcm	620	19	linked	link	VBN
cord-009417-458rrhcm	620	20	or	or	CC
cord-009417-458rrhcm	620	21	polymerized	polymerize	VBN
cord-009417-458rrhcm	620	22	by	by	IN
cord-009417-458rrhcm	620	23	chemical	chemical	JJ
cord-009417-458rrhcm	620	24	manipulation	manipulation	NN
cord-009417-458rrhcm	620	25	to	to	TO
cord-009417-458rrhcm	620	26	prevent	prevent	VB
cord-009417-458rrhcm	620	27	rapid	rapid	JJ
cord-009417-458rrhcm	620	28	clearance	clearance	NN
cord-009417-458rrhcm	620	29	from	from	IN
cord-009417-458rrhcm	620	30	the	the	DT
cord-009417-458rrhcm	620	31	circulation	circulation	NN
cord-009417-458rrhcm	620	32	.	.	.
cord-009417-458rrhcm	621	1	They	-PRON-	PRP
cord-009417-458rrhcm	621	2	are	be	VBP
cord-009417-458rrhcm	621	3	intended	intend	VBN
cord-009417-458rrhcm	621	4	to	to	TO
cord-009417-458rrhcm	621	5	provide	provide	VB
cord-009417-458rrhcm	621	6	short	short	JJ
cord-009417-458rrhcm	621	7	-	-	HYPH
cord-009417-458rrhcm	621	8	term	term	NN
cord-009417-458rrhcm	621	9	oxygen	oxygen	NN
cord-009417-458rrhcm	621	10	-	-	HYPH
cord-009417-458rrhcm	621	11	carrying	carry	VBG
cord-009417-458rrhcm	621	12	capacity	capacity	NN
cord-009417-458rrhcm	621	13	for	for	IN
cord-009417-458rrhcm	621	14	acutely	acutely	RB
cord-009417-458rrhcm	621	15	ill	ill	JJ
cord-009417-458rrhcm	621	16	patients	patient	NNS
cord-009417-458rrhcm	621	17	and	and	CC
cord-009417-458rrhcm	621	18	have	have	VBP
cord-009417-458rrhcm	621	19	the	the	DT
cord-009417-458rrhcm	621	20	advantage	advantage	NN
cord-009417-458rrhcm	621	21	of	of	IN
cord-009417-458rrhcm	621	22	not	not	RB
cord-009417-458rrhcm	621	23	requiring	require	VBG
cord-009417-458rrhcm	621	24	crossmatching	crossmatching	NN
cord-009417-458rrhcm	621	25	or	or	CC
cord-009417-458rrhcm	621	26	infection	infection	NN
cord-009417-458rrhcm	621	27	control	control	NN
cord-009417-458rrhcm	621	28	.	.	.
cord-009417-458rrhcm	622	1	Although	although	IN
cord-009417-458rrhcm	622	2	these	these	DT
cord-009417-458rrhcm	622	3	proposed	propose	VBN
cord-009417-458rrhcm	622	4	products	product	NNS
cord-009417-458rrhcm	622	5	may	may	MD
cord-009417-458rrhcm	622	6	have	have	VB
cord-009417-458rrhcm	622	7	a	a	DT
cord-009417-458rrhcm	622	8	longer	long	JJR
cord-009417-458rrhcm	622	9	shelf	shelf	NN
cord-009417-458rrhcm	622	10	-	-	HYPH
cord-009417-458rrhcm	622	11	life	life	NN
cord-009417-458rrhcm	622	12	and	and	CC
cord-009417-458rrhcm	622	13	are	be	VBP
cord-009417-458rrhcm	622	14	easier	easy	JJR
cord-009417-458rrhcm	622	15	to	to	TO
cord-009417-458rrhcm	622	16	transport	transport	VB
cord-009417-458rrhcm	622	17	,	,	,
cord-009417-458rrhcm	622	18	their	-PRON-	PRP$
cord-009417-458rrhcm	622	19	drawbacks	drawback	NNS
cord-009417-458rrhcm	622	20	are	be	VBP
cord-009417-458rrhcm	622	21	many	many	JJ
cord-009417-458rrhcm	622	22	.	.	.
cord-009417-458rrhcm	623	1	Most	Most	JJS
cord-009417-458rrhcm	623	2	have	have	VBP
cord-009417-458rrhcm	623	3	a	a	DT
cord-009417-458rrhcm	623	4	circulatory	circulatory	JJ
cord-009417-458rrhcm	623	5	half	half	JJ
cord-009417-458rrhcm	623	6	-	-	HYPH
cord-009417-458rrhcm	623	7	life	life	NN
cord-009417-458rrhcm	623	8	of	of	IN
cord-009417-458rrhcm	623	9	only	only	RB
cord-009417-458rrhcm	623	10	about	about	RB
cord-009417-458rrhcm	623	11	24	24	CD
cord-009417-458rrhcm	623	12	hours	hour	NNS
cord-009417-458rrhcm	623	13	.	.	.
cord-009417-458rrhcm	624	1	The	the	DT
cord-009417-458rrhcm	624	2	oxygen	oxygen	NN
cord-009417-458rrhcm	624	3	dissociation	dissociation	NN
cord-009417-458rrhcm	624	4	curve	curve	NN
cord-009417-458rrhcm	624	5	for	for	IN
cord-009417-458rrhcm	624	6	these	these	DT
cord-009417-458rrhcm	624	7	substitutes	substitute	NNS
cord-009417-458rrhcm	624	8	is	be	VBZ
cord-009417-458rrhcm	624	9	also	also	RB
cord-009417-458rrhcm	624	10	frequently	frequently	RB
cord-009417-458rrhcm	624	11	not	not	RB
cord-009417-458rrhcm	624	12	favorable	favorable	JJ
cord-009417-458rrhcm	624	13	:	:	:
cord-009417-458rrhcm	624	14	either	either	CC
cord-009417-458rrhcm	624	15	a	a	DT
cord-009417-458rrhcm	624	16	high	high	JJ
cord-009417-458rrhcm	624	17	FIO	FIO	NNP
cord-009417-458rrhcm	624	18	2	2	CD
cord-009417-458rrhcm	624	19	is	be	VBZ
cord-009417-458rrhcm	624	20	required	require	VBN
cord-009417-458rrhcm	624	21	to	to	TO
cord-009417-458rrhcm	624	22	"	"	``
cord-009417-458rrhcm	624	23	load	load	VB
cord-009417-458rrhcm	624	24	"	"	''
cord-009417-458rrhcm	624	25	these	these	DT
cord-009417-458rrhcm	624	26	molecules	molecule	NNS
cord-009417-458rrhcm	625	1	or	or	CC
cord-009417-458rrhcm	625	2	they	-PRON-	PRP
cord-009417-458rrhcm	625	3	are	be	VBP
cord-009417-458rrhcm	625	4	less	less	RBR
cord-009417-458rrhcm	625	5	likely	likely	JJ
cord-009417-458rrhcm	625	6	to	to	TO
cord-009417-458rrhcm	625	7	deliver	deliver	VB
cord-009417-458rrhcm	625	8	oxygen	oxygen	NN
cord-009417-458rrhcm	625	9	efficiently	efficiently	RB
cord-009417-458rrhcm	625	10	at	at	IN
cord-009417-458rrhcm	625	11	lower	low	JJR
cord-009417-458rrhcm	625	12	PO	PO	NNP
cord-009417-458rrhcm	625	13	2	2	CD
cord-009417-458rrhcm	625	14	levels	level	NNS
cord-009417-458rrhcm	625	15	.	.	.
cord-009417-458rrhcm	626	1	141	141	CD
cord-009417-458rrhcm	627	1	Because	because	IN
cord-009417-458rrhcm	627	2	the	the	DT
cord-009417-458rrhcm	627	3	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	627	4	source	source	NN
cord-009417-458rrhcm	627	5	is	be	VBZ
cord-009417-458rrhcm	627	6	reclaimed	reclaim	VBN
cord-009417-458rrhcm	627	7	bovine	bovine	JJ
cord-009417-458rrhcm	627	8	or	or	CC
cord-009417-458rrhcm	627	9	human	human	JJ
cord-009417-458rrhcm	627	10	red	red	JJ
cord-009417-458rrhcm	627	11	cells	cell	NNS
cord-009417-458rrhcm	627	12	,	,	,
cord-009417-458rrhcm	627	13	it	-PRON-	PRP
cord-009417-458rrhcm	627	14	is	be	VBZ
cord-009417-458rrhcm	627	15	unlikely	unlikely	JJ
cord-009417-458rrhcm	627	16	that	that	IN
cord-009417-458rrhcm	627	17	patients	patient	NNS
cord-009417-458rrhcm	627	18	who	who	WP
cord-009417-458rrhcm	627	19	do	do	VBP
cord-009417-458rrhcm	627	20	not	not	RB
cord-009417-458rrhcm	627	21	accept	accept	VB
cord-009417-458rrhcm	627	22	blood	blood	NN
cord-009417-458rrhcm	627	23	components	component	NNS
cord-009417-458rrhcm	627	24	because	because	IN
cord-009417-458rrhcm	627	25	of	of	IN
cord-009417-458rrhcm	627	26	their	-PRON-	PRP$
cord-009417-458rrhcm	627	27	religious	religious	JJ
cord-009417-458rrhcm	627	28	beliefs	belief	NNS
cord-009417-458rrhcm	627	29	(	(	-LRB-
cord-009417-458rrhcm	627	30	Jehovah	Jehovah	NNP
cord-009417-458rrhcm	627	31	's	's	POS
cord-009417-458rrhcm	627	32	Witnesses	Witnesses	NNPS
cord-009417-458rrhcm	627	33	)	)	-RRB-
cord-009417-458rrhcm	627	34	will	will	MD
cord-009417-458rrhcm	627	35	accept	accept	VB
cord-009417-458rrhcm	627	36	these	these	DT
cord-009417-458rrhcm	627	37	types	type	NNS
cord-009417-458rrhcm	627	38	of	of	IN
cord-009417-458rrhcm	627	39	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	627	40	solutions	solution	NNS
cord-009417-458rrhcm	627	41	.	.	.
cord-009417-458rrhcm	628	1	One	one	CD
cord-009417-458rrhcm	628	2	product	product	NN
cord-009417-458rrhcm	628	3	in	in	IN
cord-009417-458rrhcm	628	4	development	development	NN
cord-009417-458rrhcm	628	5	uses	use	VBZ
cord-009417-458rrhcm	628	6	recombinant	recombinant	JJ
cord-009417-458rrhcm	628	7	technology	technology	NN
cord-009417-458rrhcm	628	8	to	to	TO
cord-009417-458rrhcm	628	9	generate	generate	VB
cord-009417-458rrhcm	628	10	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	628	11	,	,	,
cord-009417-458rrhcm	628	12	and	and	CC
cord-009417-458rrhcm	628	13	it	-PRON-	PRP
cord-009417-458rrhcm	628	14	is	be	VBZ
cord-009417-458rrhcm	628	15	hoped	hope	VBN
cord-009417-458rrhcm	628	16	that	that	IN
cord-009417-458rrhcm	628	17	this	this	DT
cord-009417-458rrhcm	628	18	solution	solution	NN
cord-009417-458rrhcm	628	19	may	may	MD
cord-009417-458rrhcm	628	20	be	be	VB
cord-009417-458rrhcm	628	21	acceptable	acceptable	JJ
cord-009417-458rrhcm	628	22	to	to	IN
cord-009417-458rrhcm	628	23	these	these	DT
cord-009417-458rrhcm	628	24	patients	patient	NNS
cord-009417-458rrhcm	628	25	.	.	.
cord-009417-458rrhcm	629	1	The	the	DT
cord-009417-458rrhcm	629	2	licensed	licensed	JJ
cord-009417-458rrhcm	629	3	perfl	perfl	NNP
cord-009417-458rrhcm	629	4	uorocarbon	uorocarbon	NNP
cord-009417-458rrhcm	629	5	solutions	solution	NNS
cord-009417-458rrhcm	629	6	have	have	VBP
cord-009417-458rrhcm	629	7	failed	fail	VBN
cord-009417-458rrhcm	629	8	to	to	TO
cord-009417-458rrhcm	629	9	demonstrate	demonstrate	VB
cord-009417-458rrhcm	629	10	any	any	DT
cord-009417-458rrhcm	629	11	utility	utility	NN
cord-009417-458rrhcm	629	12	as	as	IN
cord-009417-458rrhcm	629	13	intravascular	intravascular	JJ
cord-009417-458rrhcm	629	14	oxygen	oxygen	NN
cord-009417-458rrhcm	629	15	carriers	carrier	NNS
cord-009417-458rrhcm	629	16	because	because	IN
cord-009417-458rrhcm	629	17	of	of	IN
cord-009417-458rrhcm	629	18	their	-PRON-	PRP$
cord-009417-458rrhcm	629	19	unfavorable	unfavorable	JJ
cord-009417-458rrhcm	629	20	P-50	P-50	NNP
cord-009417-458rrhcm	629	21	(	(	-LRB-
cord-009417-458rrhcm	629	22	oxygen	oxygen	NN
cord-009417-458rrhcm	629	23	half	half	JJ
cord-009417-458rrhcm	629	24	-	-	HYPH
cord-009417-458rrhcm	629	25	saturation	saturation	NN
cord-009417-458rrhcm	629	26	pressure	pressure	NN
cord-009417-458rrhcm	629	27	)	)	-RRB-
cord-009417-458rrhcm	629	28	and	and	CC
cord-009417-458rrhcm	629	29	oxygen	oxygen	NN
cord-009417-458rrhcm	629	30	off	off	IN
cord-009417-458rrhcm	629	31	-	-	HYPH
cord-009417-458rrhcm	629	32	loading	loading	NN
cord-009417-458rrhcm	629	33	characteristics	characteristic	NNS
cord-009417-458rrhcm	629	34	.	.	.
cord-009417-458rrhcm	630	1	They	-PRON-	PRP
cord-009417-458rrhcm	630	2	are	be	VBP
cord-009417-458rrhcm	630	3	fi	fi	IN
cord-009417-458rrhcm	630	4	nding	nde	VBG
cord-009417-458rrhcm	630	5	limited	limited	JJ
cord-009417-458rrhcm	630	6	application	application	NN
cord-009417-458rrhcm	630	7	in	in	IN
cord-009417-458rrhcm	630	8	regional	regional	JJ
cord-009417-458rrhcm	630	9	oxygenation	oxygenation	NN
cord-009417-458rrhcm	630	10	during	during	IN
cord-009417-458rrhcm	630	11	angioplasty	angioplasty	NN
cord-009417-458rrhcm	630	12	or	or	CC
cord-009417-458rrhcm	630	13	stent	stent	NN
cord-009417-458rrhcm	630	14	placement	placement	NN
cord-009417-458rrhcm	630	15	procedures	procedure	NNS
cord-009417-458rrhcm	630	16	and	and	CC
cord-009417-458rrhcm	630	17	a	a	DT
cord-009417-458rrhcm	630	18	more	more	RBR
cord-009417-458rrhcm	630	19	novel	novel	JJ
cord-009417-458rrhcm	630	20	use	use	NN
cord-009417-458rrhcm	630	21	in	in	IN
cord-009417-458rrhcm	630	22	"	"	``
cord-009417-458rrhcm	630	23	liquid	liquid	JJ
cord-009417-458rrhcm	630	24	ventilation	ventilation	NN
cord-009417-458rrhcm	630	25	.	.	.
cord-009417-458rrhcm	631	1	"	"	``
cord-009417-458rrhcm	631	2	This	this	DT
cord-009417-458rrhcm	631	3	involves	involve	VBZ
cord-009417-458rrhcm	631	4	the	the	DT
cord-009417-458rrhcm	631	5	ventilation	ventilation	NN
cord-009417-458rrhcm	631	6	of	of	IN
cord-009417-458rrhcm	631	7	intubated	intubate	VBN
cord-009417-458rrhcm	631	8	patients	patient	NNS
cord-009417-458rrhcm	631	9	experiencing	experience	VBG
cord-009417-458rrhcm	631	10	severe	severe	JJ
cord-009417-458rrhcm	631	11	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	631	12	compromise	compromise	NN
cord-009417-458rrhcm	631	13	with	with	IN
cord-009417-458rrhcm	631	14	superoxygenated	superoxygenated	NNP
cord-009417-458rrhcm	631	15	perfl	perfl	NNP
cord-009417-458rrhcm	631	16	uorocarbon	uorocarbon	NNP
cord-009417-458rrhcm	631	17	solutions	solution	NNS
cord-009417-458rrhcm	631	18	in	in	IN
cord-009417-458rrhcm	631	19	place	place	NN
cord-009417-458rrhcm	631	20	of	of	IN
cord-009417-458rrhcm	631	21	oxygen	oxygen	NN
cord-009417-458rrhcm	631	22	-	-	HYPH
cord-009417-458rrhcm	631	23	enriched	enrich	VBN
cord-009417-458rrhcm	631	24	air	air	NN
cord-009417-458rrhcm	631	25	.	.	.
cord-009417-458rrhcm	632	1	142	142	CD
cord-009417-458rrhcm	633	1	The	the	DT
cord-009417-458rrhcm	633	2	synthetic	synthetic	JJ
cord-009417-458rrhcm	633	3	vasopressin	vasopressin	NN
cord-009417-458rrhcm	633	4	analogue	analogue	NN
cord-009417-458rrhcm	633	5	DDAVP	DDAVP	NNP
cord-009417-458rrhcm	633	6	increases	increase	VBZ
cord-009417-458rrhcm	633	7	plasma	plasma	NN
cord-009417-458rrhcm	633	8	factor	factor	NN
cord-009417-458rrhcm	633	9	VIII	VIII	NNP
cord-009417-458rrhcm	633	10	:	:	:
cord-009417-458rrhcm	634	1	c	c	NNP
cord-009417-458rrhcm	634	2	and	and	CC
cord-009417-458rrhcm	634	3	promotes	promote	VBZ
cord-009417-458rrhcm	634	4	the	the	DT
cord-009417-458rrhcm	634	5	release	release	NN
cord-009417-458rrhcm	634	6	of	of	IN
cord-009417-458rrhcm	634	7	vWF	vwf	NN
cord-009417-458rrhcm	634	8	from	from	IN
cord-009417-458rrhcm	634	9	endothelial	endothelial	JJ
cord-009417-458rrhcm	634	10	stores	store	NNS
cord-009417-458rrhcm	634	11	.	.	.
cord-009417-458rrhcm	635	1	143	143	CD
cord-009417-458rrhcm	635	2	DDAVP	DDAVP	NNP
cord-009417-458rrhcm	635	3	has	have	VBZ
cord-009417-458rrhcm	635	4	provided	provide	VBN
cord-009417-458rrhcm	635	5	effective	effective	JJ
cord-009417-458rrhcm	635	6	hemostasis	hemostasis	NN
cord-009417-458rrhcm	635	7	in	in	IN
cord-009417-458rrhcm	635	8	bleeding	bleed	VBG
cord-009417-458rrhcm	635	9	patients	patient	NNS
cord-009417-458rrhcm	635	10	with	with	IN
cord-009417-458rrhcm	635	11	mild	mild	JJ
cord-009417-458rrhcm	635	12	hemophilia	hemophilia	NN
cord-009417-458rrhcm	635	13	A	a	NN
cord-009417-458rrhcm	635	14	and	and	CC
cord-009417-458rrhcm	635	15	type	type	NN
cord-009417-458rrhcm	635	16	I	-PRON-	PRP
cord-009417-458rrhcm	635	17	von	von	VBP
cord-009417-458rrhcm	635	18	Willebrand	Willebrand	NNP
cord-009417-458rrhcm	635	19	's	's	POS
cord-009417-458rrhcm	635	20	disease	disease	NN
cord-009417-458rrhcm	635	21	and	and	CC
cord-009417-458rrhcm	635	22	has	have	VBZ
cord-009417-458rrhcm	635	23	been	be	VBN
cord-009417-458rrhcm	635	24	used	use	VBN
cord-009417-458rrhcm	635	25	as	as	IN
cord-009417-458rrhcm	635	26	prophylaxis	prophylaxis	NN
cord-009417-458rrhcm	635	27	for	for	IN
cord-009417-458rrhcm	635	28	patients	patient	NNS
cord-009417-458rrhcm	635	29	undergoing	undergo	VBG
cord-009417-458rrhcm	635	30	surgery	surgery	NN
cord-009417-458rrhcm	635	31	.	.	.
cord-009417-458rrhcm	636	1	DDAVP	DDAVP	NNP
cord-009417-458rrhcm	636	2	reportedly	reportedly	RB
cord-009417-458rrhcm	636	3	improves	improve	VBZ
cord-009417-458rrhcm	636	4	platelet	platelet	NN
cord-009417-458rrhcm	636	5	function	function	NN
cord-009417-458rrhcm	636	6	in	in	IN
cord-009417-458rrhcm	636	7	some	some	DT
cord-009417-458rrhcm	636	8	patients	patient	NNS
cord-009417-458rrhcm	636	9	with	with	IN
cord-009417-458rrhcm	636	10	qualitative	qualitative	JJ
cord-009417-458rrhcm	636	11	platelet	platelet	NN
cord-009417-458rrhcm	636	12	disorders	disorder	NNS
cord-009417-458rrhcm	636	13	associated	associate	VBN
cord-009417-458rrhcm	636	14	with	with	IN
cord-009417-458rrhcm	636	15	uremia	uremia	NN
cord-009417-458rrhcm	636	16	,	,	,
cord-009417-458rrhcm	636	17	136	136	CD
cord-009417-458rrhcm	636	18	cirrhosis	cirrhosis	NN
cord-009417-458rrhcm	636	19	,	,	,
cord-009417-458rrhcm	636	20	and	and	CC
cord-009417-458rrhcm	636	21	aspirin	aspirin	NN
cord-009417-458rrhcm	636	22	ingestion	ingestion	NN
cord-009417-458rrhcm	636	23	.	.	.
cord-009417-458rrhcm	637	1	Studies	study	NNS
cord-009417-458rrhcm	637	2	of	of	IN
cord-009417-458rrhcm	637	3	its	-PRON-	PRP$
cord-009417-458rrhcm	637	4	effi	effi	NNP
cord-009417-458rrhcm	637	5	cacy	cacy	NN
cord-009417-458rrhcm	637	6	in	in	IN
cord-009417-458rrhcm	637	7	cardiopulmonary	cardiopulmonary	JJ
cord-009417-458rrhcm	637	8	bypass	bypass	NN
cord-009417-458rrhcm	637	9	procedures	procedure	NNS
cord-009417-458rrhcm	637	10	are	be	VBP
cord-009417-458rrhcm	637	11	confl	confl	NN
cord-009417-458rrhcm	637	12	icting	icting	NN
cord-009417-458rrhcm	637	13	,	,	,
cord-009417-458rrhcm	637	14	but	but	CC
cord-009417-458rrhcm	637	15	a	a	DT
cord-009417-458rrhcm	637	16	subset	subset	NN
cord-009417-458rrhcm	637	17	of	of	IN
cord-009417-458rrhcm	637	18	these	these	DT
cord-009417-458rrhcm	637	19	patients	patient	NNS
cord-009417-458rrhcm	637	20	may	may	MD
cord-009417-458rrhcm	637	21	benefi	benefi	VB
cord-009417-458rrhcm	637	22	t.	t.	NNP
cord-009417-458rrhcm	638	1	The	the	DT
cord-009417-458rrhcm	638	2	chief	chief	JJ
cord-009417-458rrhcm	638	3	drawback	drawback	NN
cord-009417-458rrhcm	638	4	to	to	IN
cord-009417-458rrhcm	638	5	its	-PRON-	PRP$
cord-009417-458rrhcm	638	6	use	use	NN
cord-009417-458rrhcm	638	7	is	be	VBZ
cord-009417-458rrhcm	638	8	tachyphylaxis	tachyphylaxis	NNP
cord-009417-458rrhcm	638	9	,	,	,
cord-009417-458rrhcm	638	10	which	which	WDT
cord-009417-458rrhcm	638	11	develops	develop	VBZ
cord-009417-458rrhcm	638	12	in	in	IN
cord-009417-458rrhcm	638	13	essentially	essentially	RB
cord-009417-458rrhcm	638	14	all	all	DT
cord-009417-458rrhcm	638	15	cases	case	NNS
cord-009417-458rrhcm	638	16	after	after	IN
cord-009417-458rrhcm	638	17	short	short	JJ
cord-009417-458rrhcm	638	18	-	-	HYPH
cord-009417-458rrhcm	638	19	term	term	NN
cord-009417-458rrhcm	638	20	repeated	repeat	VBN
cord-009417-458rrhcm	638	21	administration	administration	NN
cord-009417-458rrhcm	638	22	.	.	.
cord-009417-458rrhcm	639	1	The	the	DT
cord-009417-458rrhcm	639	2	lysine	lysine	NN
cord-009417-458rrhcm	639	3	analogues	analogue	NNS
cord-009417-458rrhcm	639	4	ε	ε	NNP
cord-009417-458rrhcm	639	5	-	-	HYPH
cord-009417-458rrhcm	639	6	aminocaproic	aminocaproic	NNP
cord-009417-458rrhcm	639	7	acid	acid	NN
cord-009417-458rrhcm	639	8	and	and	CC
cord-009417-458rrhcm	639	9	tranexamic	tranexamic	JJ
cord-009417-458rrhcm	639	10	acid	acid	NN
cord-009417-458rrhcm	640	1	inhibit	inhibit	VB
cord-009417-458rrhcm	640	2	fi	fi	IN
cord-009417-458rrhcm	640	3	brinolysis	brinolysis	NN
cord-009417-458rrhcm	640	4	by	by	IN
cord-009417-458rrhcm	640	5	blocking	block	VBG
cord-009417-458rrhcm	640	6	the	the	DT
cord-009417-458rrhcm	640	7	binding	binding	NN
cord-009417-458rrhcm	640	8	of	of	IN
cord-009417-458rrhcm	640	9	plasminogen	plasminogen	NN
cord-009417-458rrhcm	640	10	and	and	CC
cord-009417-458rrhcm	640	11	plasmin	plasmin	NN
cord-009417-458rrhcm	640	12	to	to	IN
cord-009417-458rrhcm	640	13	fi	fi	NNP
cord-009417-458rrhcm	640	14	brin	brin	NNP
cord-009417-458rrhcm	640	15	.	.	.
cord-009417-458rrhcm	641	1	These	these	DT
cord-009417-458rrhcm	641	2	antifi	antifi	NN
cord-009417-458rrhcm	641	3	brinolytic	brinolytic	JJ
cord-009417-458rrhcm	641	4	agents	agent	NNS
cord-009417-458rrhcm	641	5	may	may	MD
cord-009417-458rrhcm	641	6	decrease	decrease	VB
cord-009417-458rrhcm	641	7	bleeding	bleed	VBG
cord-009417-458rrhcm	641	8	and	and	CC
cord-009417-458rrhcm	641	9	thus	thus	RB
cord-009417-458rrhcm	641	10	the	the	DT
cord-009417-458rrhcm	641	11	need	need	NN
cord-009417-458rrhcm	641	12	for	for	IN
cord-009417-458rrhcm	641	13	homologous	homologous	JJ
cord-009417-458rrhcm	641	14	blood	blood	NN
cord-009417-458rrhcm	641	15	components	component	NNS
cord-009417-458rrhcm	641	16	in	in	IN
cord-009417-458rrhcm	641	17	patients	patient	NNS
cord-009417-458rrhcm	641	18	with	with	IN
cord-009417-458rrhcm	641	19	hemophilia	hemophilia	NN
cord-009417-458rrhcm	641	20	,	,	,
cord-009417-458rrhcm	641	21	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	641	22	,	,	,
cord-009417-458rrhcm	641	23	and	and	CC
cord-009417-458rrhcm	641	24	systemic	systemic	JJ
cord-009417-458rrhcm	641	25	fi	fi	NN
cord-009417-458rrhcm	641	26	brinolysis	brinolysis	NN
cord-009417-458rrhcm	641	27	.	.	.
cord-009417-458rrhcm	642	1	A	a	DT
cord-009417-458rrhcm	642	2	novel	novel	JJ
cord-009417-458rrhcm	642	3	and	and	CC
cord-009417-458rrhcm	642	4	effective	effective	JJ
cord-009417-458rrhcm	642	5	use	use	NN
cord-009417-458rrhcm	642	6	of	of	IN
cord-009417-458rrhcm	642	7	tranexamic	tranexamic	JJ
cord-009417-458rrhcm	642	8	acid	acid	NN
cord-009417-458rrhcm	642	9	involves	involve	VBZ
cord-009417-458rrhcm	642	10	administration	administration	NN
cord-009417-458rrhcm	642	11	as	as	IN
cord-009417-458rrhcm	642	12	a	a	DT
cord-009417-458rrhcm	642	13	mouthwash	mouthwash	NN
cord-009417-458rrhcm	642	14	in	in	IN
cord-009417-458rrhcm	642	15	preparation	preparation	NN
cord-009417-458rrhcm	642	16	for	for	IN
cord-009417-458rrhcm	642	17	oral	oral	JJ
cord-009417-458rrhcm	642	18	surgery	surgery	NN
cord-009417-458rrhcm	642	19	in	in	IN
cord-009417-458rrhcm	642	20	patients	patient	NNS
cord-009417-458rrhcm	642	21	with	with	IN
cord-009417-458rrhcm	642	22	hemophilia	hemophilia	NN
cord-009417-458rrhcm	642	23	or	or	CC
cord-009417-458rrhcm	642	24	those	those	DT
cord-009417-458rrhcm	642	25	receiving	receive	VBG
cord-009417-458rrhcm	642	26	oral	oral	JJ
cord-009417-458rrhcm	642	27	anticoagulant	anticoagulant	NN
cord-009417-458rrhcm	642	28	therapy	therapy	NN
cord-009417-458rrhcm	642	29	.	.	.
cord-009417-458rrhcm	643	1	144	144	CD
cord-009417-458rrhcm	644	1	The	the	DT
cord-009417-458rrhcm	644	2	most	most	RBS
cord-009417-458rrhcm	644	3	serious	serious	JJ
cord-009417-458rrhcm	644	4	side	side	NN
cord-009417-458rrhcm	644	5	effect	effect	NN
cord-009417-458rrhcm	644	6	of	of	IN
cord-009417-458rrhcm	644	7	these	these	DT
cord-009417-458rrhcm	644	8	agents	agent	NNS
cord-009417-458rrhcm	644	9	when	when	WRB
cord-009417-458rrhcm	644	10	systemically	systemically	RB
cord-009417-458rrhcm	644	11	administered	administer	VBN
cord-009417-458rrhcm	644	12	is	be	VBZ
cord-009417-458rrhcm	644	13	thrombosis	thrombosis	NN
cord-009417-458rrhcm	644	14	;	;	:
cord-009417-458rrhcm	644	15	thus	thus	RB
cord-009417-458rrhcm	644	16	,	,	,
cord-009417-458rrhcm	644	17	it	-PRON-	PRP
cord-009417-458rrhcm	644	18	is	be	VBZ
cord-009417-458rrhcm	644	19	important	important	JJ
cord-009417-458rrhcm	644	20	to	to	TO
cord-009417-458rrhcm	644	21	use	use	VB
cord-009417-458rrhcm	644	22	them	-PRON-	PRP
cord-009417-458rrhcm	644	23	appropriately	appropriately	RB
cord-009417-458rrhcm	644	24	and	and	CC
cord-009417-458rrhcm	644	25	monitor	monitor	VB
cord-009417-458rrhcm	644	26	the	the	DT
cord-009417-458rrhcm	644	27	patient	patient	NN
cord-009417-458rrhcm	644	28	carefully	carefully	RB
cord-009417-458rrhcm	644	29	during	during	IN
cord-009417-458rrhcm	644	30	their	-PRON-	PRP$
cord-009417-458rrhcm	644	31	use	use	NN
cord-009417-458rrhcm	644	32	.	.	.
cord-009417-458rrhcm	645	1	Aprotinin	Aprotinin	NNP
cord-009417-458rrhcm	645	2	is	be	VBZ
cord-009417-458rrhcm	645	3	a	a	DT
cord-009417-458rrhcm	645	4	naturally	naturally	RB
cord-009417-458rrhcm	645	5	occurring	occur	VBG
cord-009417-458rrhcm	645	6	bovine	bovine	JJ
cord-009417-458rrhcm	645	7	serine	serine	NN
cord-009417-458rrhcm	645	8	protease	protease	NN
cord-009417-458rrhcm	645	9	inhibitor	inhibitor	NN
cord-009417-458rrhcm	645	10	that	that	WDT
cord-009417-458rrhcm	645	11	acts	act	VBZ
cord-009417-458rrhcm	645	12	on	on	IN
cord-009417-458rrhcm	645	13	plasma	plasma	NN
cord-009417-458rrhcm	645	14	serine	serine	NN
cord-009417-458rrhcm	645	15	proteases	protease	NNS
cord-009417-458rrhcm	645	16	such	such	JJ
cord-009417-458rrhcm	645	17	as	as	IN
cord-009417-458rrhcm	645	18	plasmin	plasmin	NNP
cord-009417-458rrhcm	645	19	,	,	,
cord-009417-458rrhcm	645	20	kallikrein	kallikrein	NNP
cord-009417-458rrhcm	645	21	,	,	,
cord-009417-458rrhcm	645	22	trypsin	trypsin	NN
cord-009417-458rrhcm	645	23	,	,	,
cord-009417-458rrhcm	645	24	and	and	CC
cord-009417-458rrhcm	645	25	some	some	DT
cord-009417-458rrhcm	645	26	coagulation	coagulation	NN
cord-009417-458rrhcm	645	27	proteins	protein	NNS
cord-009417-458rrhcm	645	28	.	.	.
cord-009417-458rrhcm	646	1	Aprotinin	Aprotinin	NNP
cord-009417-458rrhcm	646	2	has	have	VBZ
cord-009417-458rrhcm	646	3	been	be	VBN
cord-009417-458rrhcm	646	4	shown	show	VBN
cord-009417-458rrhcm	646	5	to	to	TO
cord-009417-458rrhcm	646	6	reduce	reduce	VB
cord-009417-458rrhcm	646	7	blood	blood	NN
cord-009417-458rrhcm	646	8	loss	loss	NN
cord-009417-458rrhcm	646	9	in	in	IN
cord-009417-458rrhcm	646	10	patients	patient	NNS
cord-009417-458rrhcm	646	11	undergoing	undergo	VBG
cord-009417-458rrhcm	646	12	cardiopulmonary	cardiopulmonary	JJ
cord-009417-458rrhcm	646	13	bypass	bypass	NN
cord-009417-458rrhcm	646	14	surgery	surgery	NN
cord-009417-458rrhcm	646	15	145	145	CD
cord-009417-458rrhcm	646	16	by	by	IN
cord-009417-458rrhcm	646	17	inhibiting	inhibit	VBG
cord-009417-458rrhcm	646	18	fi	fi	NN
cord-009417-458rrhcm	646	19	brinolysis	brinolysis	NN
cord-009417-458rrhcm	646	20	and	and	CC
cord-009417-458rrhcm	646	21	preventing	prevent	VBG
cord-009417-458rrhcm	646	22	platelet	platelet	NN
cord-009417-458rrhcm	646	23	damage	damage	NN
cord-009417-458rrhcm	646	24	.	.	.
cord-009417-458rrhcm	647	1	However	however	RB
cord-009417-458rrhcm	647	2	,	,	,
cord-009417-458rrhcm	647	3	more	more	RBR
cord-009417-458rrhcm	647	4	recent	recent	JJ
cord-009417-458rrhcm	647	5	reports	report	NNS
cord-009417-458rrhcm	647	6	of	of	IN
cord-009417-458rrhcm	647	7	renal	renal	JJ
cord-009417-458rrhcm	647	8	injury	injury	NN
cord-009417-458rrhcm	647	9	and	and	CC
cord-009417-458rrhcm	647	10	longterm	longterm	JJ
cord-009417-458rrhcm	647	11	mortality	mortality	NN
cord-009417-458rrhcm	647	12	may	may	MD
cord-009417-458rrhcm	647	13	mean	mean	VB
cord-009417-458rrhcm	647	14	an	an	DT
cord-009417-458rrhcm	647	15	end	end	NN
cord-009417-458rrhcm	647	16	to	to	IN
cord-009417-458rrhcm	647	17	its	-PRON-	PRP$
cord-009417-458rrhcm	647	18	use	use	NN
cord-009417-458rrhcm	647	19	.	.	.
cord-009417-458rrhcm	648	1	146	146	CD
cord-009417-458rrhcm	648	2	Aprotinin	Aprotinin	NNP
cord-009417-458rrhcm	648	3	has	have	VBZ
cord-009417-458rrhcm	648	4	been	be	VBN
cord-009417-458rrhcm	648	5	used	use	VBN
cord-009417-458rrhcm	648	6	extensively	extensively	RB
cord-009417-458rrhcm	648	7	in	in	IN
cord-009417-458rrhcm	648	8	liver	liver	NN
cord-009417-458rrhcm	648	9	transplantation	transplantation	NN
cord-009417-458rrhcm	648	10	,	,	,
cord-009417-458rrhcm	648	11	which	which	WDT
cord-009417-458rrhcm	648	12	involves	involve	VBZ
cord-009417-458rrhcm	648	13	high	high	JJ
cord-009417-458rrhcm	648	14	blood	blood	NN
cord-009417-458rrhcm	648	15	loss	loss	NN
cord-009417-458rrhcm	648	16	.	.	.
cord-009417-458rrhcm	649	1	Repeated	repeat	VBN
cord-009417-458rrhcm	649	2	administration	administration	NN
cord-009417-458rrhcm	649	3	poses	pose	VBZ
cord-009417-458rrhcm	649	4	the	the	DT
cord-009417-458rrhcm	649	5	risk	risk	NN
cord-009417-458rrhcm	649	6	of	of	IN
cord-009417-458rrhcm	649	7	anaphylaxis	anaphylaxis	NN
cord-009417-458rrhcm	649	8	and	and	CC
cord-009417-458rrhcm	649	9	renal	renal	JJ
cord-009417-458rrhcm	649	10	dysfunction	dysfunction	NN
cord-009417-458rrhcm	649	11	.	.	.
cord-009417-458rrhcm	650	1	When	when	WRB
cord-009417-458rrhcm	650	2	time	time	NN
cord-009417-458rrhcm	650	3	permits	permit	NNS
cord-009417-458rrhcm	650	4	,	,	,
cord-009417-458rrhcm	650	5	vitamin	vitamin	NN
cord-009417-458rrhcm	650	6	K	K	NNP
cord-009417-458rrhcm	650	7	is	be	VBZ
cord-009417-458rrhcm	650	8	the	the	DT
cord-009417-458rrhcm	650	9	preferred	preferred	JJ
cord-009417-458rrhcm	650	10	agent	agent	NN
cord-009417-458rrhcm	650	11	to	to	TO
cord-009417-458rrhcm	650	12	reverse	reverse	VB
cord-009417-458rrhcm	650	13	the	the	DT
cord-009417-458rrhcm	650	14	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	650	15	induced	induce	VBN
cord-009417-458rrhcm	650	16	by	by	IN
cord-009417-458rrhcm	650	17	oral	oral	JJ
cord-009417-458rrhcm	650	18	anticoagulants	anticoagulant	NNS
cord-009417-458rrhcm	650	19	.	.	.
cord-009417-458rrhcm	651	1	Normalization	normalization	NN
cord-009417-458rrhcm	651	2	of	of	IN
cord-009417-458rrhcm	651	3	the	the	DT
cord-009417-458rrhcm	651	4	PT	pt	NN
cord-009417-458rrhcm	651	5	can	can	MD
cord-009417-458rrhcm	651	6	be	be	VB
cord-009417-458rrhcm	651	7	seen	see	VBN
cord-009417-458rrhcm	651	8	in	in	IN
cord-009417-458rrhcm	651	9	as	as	RB
cord-009417-458rrhcm	651	10	few	few	JJ
cord-009417-458rrhcm	651	11	as	as	IN
cord-009417-458rrhcm	651	12	6	6	CD
cord-009417-458rrhcm	651	13	to	to	TO
cord-009417-458rrhcm	651	14	12	12	CD
cord-009417-458rrhcm	651	15	hours	hour	NNS
cord-009417-458rrhcm	651	16	.	.	.
cord-009417-458rrhcm	652	1	Additionally	additionally	RB
cord-009417-458rrhcm	652	2	,	,	,
cord-009417-458rrhcm	652	3	selected	select	VBN
cord-009417-458rrhcm	652	4	cirrhotic	cirrhotic	JJ
cord-009417-458rrhcm	652	5	patients	patient	NNS
cord-009417-458rrhcm	652	6	may	may	MD
cord-009417-458rrhcm	652	7	exhibit	exhibit	VB
cord-009417-458rrhcm	652	8	improvement	improvement	NN
cord-009417-458rrhcm	652	9	in	in	IN
cord-009417-458rrhcm	652	10	the	the	DT
cord-009417-458rrhcm	652	11	PT	pt	NN
cord-009417-458rrhcm	652	12	when	when	WRB
cord-009417-458rrhcm	652	13	treated	treat	VBN
cord-009417-458rrhcm	652	14	with	with	IN
cord-009417-458rrhcm	652	15	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	652	16	doses	dose	NNS
cord-009417-458rrhcm	652	17	of	of	IN
cord-009417-458rrhcm	652	18	vitamin	vitamin	NN
cord-009417-458rrhcm	653	1	K.	K.	NNP
cord-009417-458rrhcm	653	2	Many	many	JJ
cord-009417-458rrhcm	653	3	patients	patient	NNS
cord-009417-458rrhcm	653	4	in	in	IN
cord-009417-458rrhcm	653	5	critical	critical	JJ
cord-009417-458rrhcm	653	6	care	care	NN
cord-009417-458rrhcm	653	7	units	unit	NNS
cord-009417-458rrhcm	653	8	exhibit	exhibit	VBP
cord-009417-458rrhcm	653	9	a	a	DT
cord-009417-458rrhcm	653	10	prolonged	prolonged	JJ
cord-009417-458rrhcm	653	11	PT	pt	NN
cord-009417-458rrhcm	653	12	,	,	,
cord-009417-458rrhcm	653	13	especially	especially	RB
cord-009417-458rrhcm	653	14	if	if	IN
cord-009417-458rrhcm	653	15	dietary	dietary	JJ
cord-009417-458rrhcm	653	16	supplements	supplement	NNS
cord-009417-458rrhcm	653	17	are	be	VBP
cord-009417-458rrhcm	653	18	limited	limited	JJ
cord-009417-458rrhcm	653	19	and	and	CC
cord-009417-458rrhcm	653	20	broad	broad	JJ
cord-009417-458rrhcm	653	21	-	-	HYPH
cord-009417-458rrhcm	653	22	spectrum	spectrum	NN
cord-009417-458rrhcm	653	23	antibiotic	antibiotic	NN
cord-009417-458rrhcm	653	24	therapy	therapy	NN
cord-009417-458rrhcm	653	25	is	be	VBZ
cord-009417-458rrhcm	653	26	given	give	VBN
cord-009417-458rrhcm	653	27	.	.	.
cord-009417-458rrhcm	654	1	Vitamin	vitamin	NN
cord-009417-458rrhcm	654	2	K	k	NN
cord-009417-458rrhcm	654	3	is	be	VBZ
cord-009417-458rrhcm	654	4	a	a	DT
cord-009417-458rrhcm	654	5	safe	safe	JJ
cord-009417-458rrhcm	654	6	and	and	CC
cord-009417-458rrhcm	654	7	effective	effective	JJ
cord-009417-458rrhcm	654	8	agent	agent	NN
cord-009417-458rrhcm	654	9	for	for	IN
cord-009417-458rrhcm	654	10	reversing	reverse	VBG
cord-009417-458rrhcm	654	11	this	this	DT
cord-009417-458rrhcm	654	12	effect	effect	NN
cord-009417-458rrhcm	654	13	.	.	.
cord-009417-458rrhcm	655	1	Recombinant	recombinant	JJ
cord-009417-458rrhcm	655	2	erythropoietin	erythropoietin	NN
cord-009417-458rrhcm	655	3	(	(	-LRB-
cord-009417-458rrhcm	655	4	EPO	EPO	NNP
cord-009417-458rrhcm	655	5	)	)	-RRB-
cord-009417-458rrhcm	655	6	has	have	VBZ
cord-009417-458rrhcm	655	7	dramatically	dramatically	RB
cord-009417-458rrhcm	655	8	reduced	reduce	VBN
cord-009417-458rrhcm	655	9	the	the	DT
cord-009417-458rrhcm	655	10	red	red	JJ
cord-009417-458rrhcm	655	11	cell	cell	NN
cord-009417-458rrhcm	655	12	transfusion	transfusion	NN
cord-009417-458rrhcm	655	13	requirements	requirement	NNS
cord-009417-458rrhcm	655	14	of	of	IN
cord-009417-458rrhcm	655	15	patients	patient	NNS
cord-009417-458rrhcm	655	16	in	in	IN
cord-009417-458rrhcm	655	17	chronic	chronic	JJ
cord-009417-458rrhcm	655	18	renal	renal	JJ
cord-009417-458rrhcm	655	19	failure	failure	NN
cord-009417-458rrhcm	655	20	.	.	.
cord-009417-458rrhcm	656	1	EPO	EPO	NNP
cord-009417-458rrhcm	656	2	also	also	RB
cord-009417-458rrhcm	656	3	has	have	VBZ
cord-009417-458rrhcm	656	4	applications	application	NNS
cord-009417-458rrhcm	656	5	in	in	IN
cord-009417-458rrhcm	656	6	the	the	DT
cord-009417-458rrhcm	656	7	adjunctive	adjunctive	JJ
cord-009417-458rrhcm	656	8	treatment	treatment	NN
cord-009417-458rrhcm	656	9	of	of	IN
cord-009417-458rrhcm	656	10	the	the	DT
cord-009417-458rrhcm	656	11	anemia	anemia	NN
cord-009417-458rrhcm	656	12	of	of	IN
cord-009417-458rrhcm	656	13	premature	premature	JJ
cord-009417-458rrhcm	656	14	infants	infant	NNS
cord-009417-458rrhcm	656	15	and	and	CC
cord-009417-458rrhcm	656	16	the	the	DT
cord-009417-458rrhcm	656	17	anemia	anemia	NN
cord-009417-458rrhcm	656	18	of	of	IN
cord-009417-458rrhcm	656	19	chronic	chronic	JJ
cord-009417-458rrhcm	656	20	disease	disease	NN
cord-009417-458rrhcm	656	21	,	,	,
cord-009417-458rrhcm	656	22	especially	especially	RB
cord-009417-458rrhcm	656	23	rheumatoid	rheumatoid	JJ
cord-009417-458rrhcm	656	24	arthritis	arthritis	NN
cord-009417-458rrhcm	656	25	,	,	,
cord-009417-458rrhcm	656	26	cancer	cancer	NN
cord-009417-458rrhcm	656	27	,	,	,
cord-009417-458rrhcm	656	28	and	and	CC
cord-009417-458rrhcm	656	29	AIDS	AIDS	NNP
cord-009417-458rrhcm	656	30	.	.	.
cord-009417-458rrhcm	657	1	Studies	study	NNS
cord-009417-458rrhcm	657	2	of	of	IN
cord-009417-458rrhcm	657	3	its	-PRON-	PRP$
cord-009417-458rrhcm	657	4	effi	effi	NNP
cord-009417-458rrhcm	657	5	cacy	cacy	NN
cord-009417-458rrhcm	657	6	in	in	IN
cord-009417-458rrhcm	657	7	reducing	reduce	VBG
cord-009417-458rrhcm	657	8	perioperative	perioperative	JJ
cord-009417-458rrhcm	657	9	red	red	JJ
cord-009417-458rrhcm	657	10	cell	cell	NN
cord-009417-458rrhcm	657	11	transfusion	transfusion	NN
cord-009417-458rrhcm	657	12	requirements	requirement	NNS
cord-009417-458rrhcm	657	13	by	by	IN
cord-009417-458rrhcm	657	14	increasing	increase	VBG
cord-009417-458rrhcm	657	15	the	the	DT
cord-009417-458rrhcm	657	16	yield	yield	NN
cord-009417-458rrhcm	657	17	of	of	IN
cord-009417-458rrhcm	657	18	predeposited	predeposited	JJ
cord-009417-458rrhcm	657	19	autologous	autologous	JJ
cord-009417-458rrhcm	657	20	blood	blood	NN
cord-009417-458rrhcm	657	21	or	or	CC
cord-009417-458rrhcm	657	22	stimulating	stimulate	VBG
cord-009417-458rrhcm	657	23	bone	bone	NN
cord-009417-458rrhcm	657	24	marrow	marrow	NN
cord-009417-458rrhcm	657	25	synthesis	synthesis	NN
cord-009417-458rrhcm	657	26	after	after	IN
cord-009417-458rrhcm	657	27	surgery	surgery	NN
cord-009417-458rrhcm	657	28	have	have	VBP
cord-009417-458rrhcm	657	29	shown	show	VBN
cord-009417-458rrhcm	657	30	benefi	benefi	NNP
cord-009417-458rrhcm	657	31	t	t	NN
cord-009417-458rrhcm	657	32	in	in	IN
cord-009417-458rrhcm	657	33	reducing	reduce	VBG
cord-009417-458rrhcm	657	34	blood	blood	NN
cord-009417-458rrhcm	657	35	transfusion	transfusion	NN
cord-009417-458rrhcm	657	36	,	,	,
cord-009417-458rrhcm	657	37	although	although	IN
cord-009417-458rrhcm	657	38	preoperative	preoperative	JJ
cord-009417-458rrhcm	657	39	planning	planning	NN
cord-009417-458rrhcm	657	40	and	and	CC
cord-009417-458rrhcm	657	41	autologous	autologous	JJ
cord-009417-458rrhcm	657	42	deposits	deposit	NNS
cord-009417-458rrhcm	657	43	are	be	VBP
cord-009417-458rrhcm	657	44	required	require	VBN
cord-009417-458rrhcm	657	45	.	.	.
cord-009417-458rrhcm	658	1	147	147	CD
cord-009417-458rrhcm	659	1	In	in	IN
cord-009417-458rrhcm	659	2	contrast	contrast	NN
cord-009417-458rrhcm	659	3	and	and	CC
cord-009417-458rrhcm	659	4	probably	probably	RB
cord-009417-458rrhcm	659	5	because	because	IN
cord-009417-458rrhcm	659	6	the	the	DT
cord-009417-458rrhcm	659	7	impact	impact	NN
cord-009417-458rrhcm	659	8	of	of	IN
cord-009417-458rrhcm	659	9	EPO	EPO	NNP
cord-009417-458rrhcm	659	10	is	be	VBZ
cord-009417-458rrhcm	659	11	not	not	RB
cord-009417-458rrhcm	659	12	immediate	immediate	JJ
cord-009417-458rrhcm	659	13	,	,	,
cord-009417-458rrhcm	659	14	the	the	DT
cord-009417-458rrhcm	659	15	effi	effi	NNP
cord-009417-458rrhcm	659	16	cacy	cacy	NN
cord-009417-458rrhcm	659	17	of	of	IN
cord-009417-458rrhcm	659	18	EPO	EPO	NNP
cord-009417-458rrhcm	659	19	in	in	IN
cord-009417-458rrhcm	659	20	the	the	DT
cord-009417-458rrhcm	659	21	ICU	ICU	NNP
cord-009417-458rrhcm	659	22	is	be	VBZ
cord-009417-458rrhcm	659	23	unproven	unproven	JJ
cord-009417-458rrhcm	659	24	and	and	CC
cord-009417-458rrhcm	659	25	awaits	await	VBZ
cord-009417-458rrhcm	659	26	the	the	DT
cord-009417-458rrhcm	659	27	results	result	NNS
cord-009417-458rrhcm	659	28	of	of	IN
cord-009417-458rrhcm	659	29	large	large	JJ
cord-009417-458rrhcm	659	30	clinical	clinical	JJ
cord-009417-458rrhcm	659	31	trials	trial	NNS
cord-009417-458rrhcm	659	32	.	.	.
cord-009417-458rrhcm	660	1	Recombinant	recombinant	JJ
cord-009417-458rrhcm	660	2	growth	growth	NN
cord-009417-458rrhcm	660	3	factors	factor	NNS
cord-009417-458rrhcm	660	4	such	such	JJ
cord-009417-458rrhcm	660	5	as	as	IN
cord-009417-458rrhcm	660	6	granulocytemacrophage	granulocytemacrophage	NN
cord-009417-458rrhcm	660	7	colony	colony	NN
cord-009417-458rrhcm	660	8	-	-	HYPH
cord-009417-458rrhcm	660	9	stimulating	stimulate	VBG
cord-009417-458rrhcm	660	10	factor	factor	NN
cord-009417-458rrhcm	660	11	(	(	-LRB-
cord-009417-458rrhcm	660	12	GM	GM	NNP
cord-009417-458rrhcm	660	13	-	-	HYPH
cord-009417-458rrhcm	660	14	CSF	CSF	NNP
cord-009417-458rrhcm	660	15	)	)	-RRB-
cord-009417-458rrhcm	660	16	and	and	CC
cord-009417-458rrhcm	660	17	G	G	NNP
cord-009417-458rrhcm	660	18	-	-	HYPH
cord-009417-458rrhcm	660	19	CSF	csf	NN
cord-009417-458rrhcm	660	20	stimulate	stimulate	VBP
cord-009417-458rrhcm	660	21	marrow	marrow	NN
cord-009417-458rrhcm	660	22	production	production	NN
cord-009417-458rrhcm	660	23	of	of	IN
cord-009417-458rrhcm	660	24	leukocytes	leukocyte	NNS
cord-009417-458rrhcm	660	25	by	by	IN
cord-009417-458rrhcm	660	26	enhancing	enhance	VBG
cord-009417-458rrhcm	660	27	several	several	JJ
cord-009417-458rrhcm	660	28	different	different	JJ
cord-009417-458rrhcm	660	29	granulocyte	granulocyte	NN
cord-009417-458rrhcm	660	30	and	and	CC
cord-009417-458rrhcm	660	31	macrophage	macrophage	NN
cord-009417-458rrhcm	660	32	functions	function	NNS
cord-009417-458rrhcm	660	33	.	.	.
cord-009417-458rrhcm	661	1	These	these	DT
cord-009417-458rrhcm	661	2	agents	agent	NNS
cord-009417-458rrhcm	661	3	are	be	VBP
cord-009417-458rrhcm	661	4	fi	fi	NNP
cord-009417-458rrhcm	661	5	nding	nding	NN
cord-009417-458rrhcm	661	6	application	application	NN
cord-009417-458rrhcm	661	7	in	in	IN
cord-009417-458rrhcm	661	8	reducing	reduce	VBG
cord-009417-458rrhcm	661	9	the	the	DT
cord-009417-458rrhcm	661	10	neutropenic	neutropenic	JJ
cord-009417-458rrhcm	661	11	period	period	NN
cord-009417-458rrhcm	661	12	in	in	IN
cord-009417-458rrhcm	661	13	BMT	BMT	NNP
cord-009417-458rrhcm	661	14	and	and	CC
cord-009417-458rrhcm	662	1	cancer	cancer	NN
cord-009417-458rrhcm	662	2	chemotherapy	chemotherapy	NN
cord-009417-458rrhcm	662	3	by	by	IN
cord-009417-458rrhcm	662	4	increasing	increase	VBG
cord-009417-458rrhcm	662	5	the	the	DT
cord-009417-458rrhcm	662	6	leukocyte	leukocyte	NN
cord-009417-458rrhcm	662	7	count	count	NN
cord-009417-458rrhcm	662	8	in	in	IN
cord-009417-458rrhcm	662	9	hypoproliferative	hypoproliferative	JJ
cord-009417-458rrhcm	662	10	marrow	marrow	NN
cord-009417-458rrhcm	662	11	conditions	condition	NNS
cord-009417-458rrhcm	662	12	.	.	.
cord-009417-458rrhcm	663	1	These	these	DT
cord-009417-458rrhcm	663	2	myeloid	myeloid	JJ
cord-009417-458rrhcm	663	3	growth	growth	NN
cord-009417-458rrhcm	663	4	factors	factor	NNS
cord-009417-458rrhcm	663	5	are	be	VBP
cord-009417-458rrhcm	663	6	replacing	replace	VBG
cord-009417-458rrhcm	663	7	granulocyte	granulocyte	NN
cord-009417-458rrhcm	663	8	transfusions	transfusion	NNS
cord-009417-458rrhcm	663	9	for	for	IN
cord-009417-458rrhcm	663	10	their	-PRON-	PRP$
cord-009417-458rrhcm	663	11	few	few	JJ
cord-009417-458rrhcm	663	12	remaining	remain	VBG
cord-009417-458rrhcm	663	13	indications	indication	NNS
cord-009417-458rrhcm	663	14	.	.	.
cord-009417-458rrhcm	664	1	Cell	cell	NN
cord-009417-458rrhcm	664	2	salvage	salvage	NN
cord-009417-458rrhcm	664	3	equipment	equipment	NN
cord-009417-458rrhcm	664	4	has	have	VBZ
cord-009417-458rrhcm	664	5	been	be	VBN
cord-009417-458rrhcm	664	6	in	in	IN
cord-009417-458rrhcm	664	7	clinical	clinical	JJ
cord-009417-458rrhcm	664	8	use	use	NN
cord-009417-458rrhcm	664	9	for	for	IN
cord-009417-458rrhcm	664	10	several	several	JJ
cord-009417-458rrhcm	664	11	decades	decade	NNS
cord-009417-458rrhcm	664	12	,	,	,
cord-009417-458rrhcm	664	13	and	and	CC
cord-009417-458rrhcm	664	14	although	although	IN
cord-009417-458rrhcm	664	15	cell	cell	NN
cord-009417-458rrhcm	664	16	salvage	salvage	NN
cord-009417-458rrhcm	664	17	is	be	VBZ
cord-009417-458rrhcm	664	18	clearly	clearly	RB
cord-009417-458rrhcm	664	19	capable	capable	JJ
cord-009417-458rrhcm	664	20	of	of	IN
cord-009417-458rrhcm	664	21	rescuing	rescue	VBG
cord-009417-458rrhcm	664	22	otherwise	otherwise	RB
cord-009417-458rrhcm	664	23	"	"	``
cord-009417-458rrhcm	664	24	lost	lose	VBN
cord-009417-458rrhcm	664	25	"	"	''
cord-009417-458rrhcm	664	26	red	red	JJ
cord-009417-458rrhcm	664	27	cells	cell	NNS
cord-009417-458rrhcm	664	28	,	,	,
cord-009417-458rrhcm	664	29	its	-PRON-	PRP$
cord-009417-458rrhcm	664	30	full	full	JJ
cord-009417-458rrhcm	664	31	impact	impact	NN
cord-009417-458rrhcm	664	32	on	on	IN
cord-009417-458rrhcm	664	33	transfusions	transfusion	NNS
cord-009417-458rrhcm	664	34	has	have	VBZ
cord-009417-458rrhcm	664	35	been	be	VBN
cord-009417-458rrhcm	664	36	poorly	poorly	RB
cord-009417-458rrhcm	664	37	documented	document	VBN
cord-009417-458rrhcm	664	38	.	.	.
cord-009417-458rrhcm	665	1	Cell	cell	NN
cord-009417-458rrhcm	665	2	salvage	salvage	NN
cord-009417-458rrhcm	665	3	generally	generally	RB
cord-009417-458rrhcm	665	4	consists	consist	VBZ
cord-009417-458rrhcm	665	5	of	of	IN
cord-009417-458rrhcm	665	6	collection	collection	NN
cord-009417-458rrhcm	665	7	of	of	IN
cord-009417-458rrhcm	665	8	shed	shed	JJ
cord-009417-458rrhcm	665	9	blood	blood	NN
cord-009417-458rrhcm	665	10	from	from	IN
cord-009417-458rrhcm	665	11	a	a	DT
cord-009417-458rrhcm	665	12	clean	clean	JJ
cord-009417-458rrhcm	665	13	,	,	,
cord-009417-458rrhcm	665	14	uncontaminated	uncontaminated	JJ
cord-009417-458rrhcm	665	15	operating	operating	NN
cord-009417-458rrhcm	665	16	fi	fi	NNP
cord-009417-458rrhcm	665	17	eld	eld	NN
cord-009417-458rrhcm	665	18	,	,	,
cord-009417-458rrhcm	665	19	followed	follow	VBN
cord-009417-458rrhcm	665	20	by	by	IN
cord-009417-458rrhcm	665	21	removal	removal	NN
cord-009417-458rrhcm	665	22	of	of	IN
cord-009417-458rrhcm	665	23	the	the	DT
cord-009417-458rrhcm	665	24	cellular	cellular	JJ
cord-009417-458rrhcm	665	25	elements	element	NNS
cord-009417-458rrhcm	665	26	and	and	CC
cord-009417-458rrhcm	665	27	retransfusion	retransfusion	NN
cord-009417-458rrhcm	665	28	into	into	IN
cord-009417-458rrhcm	665	29	the	the	DT
cord-009417-458rrhcm	665	30	patient	patient	NN
cord-009417-458rrhcm	665	31	.	.	.
cord-009417-458rrhcm	666	1	Cell	cell	NN
cord-009417-458rrhcm	666	2	salvage	salvage	NN
cord-009417-458rrhcm	666	3	has	have	VBZ
cord-009417-458rrhcm	666	4	been	be	VBN
cord-009417-458rrhcm	666	5	used	use	VBN
cord-009417-458rrhcm	666	6	both	both	CC
cord-009417-458rrhcm	666	7	intraoperatively	intraoperatively	RB
cord-009417-458rrhcm	666	8	and	and	CC
cord-009417-458rrhcm	666	9	postoperatively	postoperatively	RB
cord-009417-458rrhcm	666	10	,	,	,
cord-009417-458rrhcm	666	11	especially	especially	RB
cord-009417-458rrhcm	666	12	in	in	IN
cord-009417-458rrhcm	666	13	cardiac	cardiac	JJ
cord-009417-458rrhcm	666	14	surgery	surgery	NN
cord-009417-458rrhcm	666	15	.	.	.
cord-009417-458rrhcm	667	1	Although	although	IN
cord-009417-458rrhcm	667	2	the	the	DT
cord-009417-458rrhcm	667	3	clinical	clinical	JJ
cord-009417-458rrhcm	667	4	studies	study	NNS
cord-009417-458rrhcm	667	5	of	of	IN
cord-009417-458rrhcm	667	6	cell	cell	NN
cord-009417-458rrhcm	667	7	salvage	salvage	NN
cord-009417-458rrhcm	667	8	have	have	VBP
cord-009417-458rrhcm	667	9	many	many	JJ
cord-009417-458rrhcm	667	10	fl	fl	NNP
cord-009417-458rrhcm	667	11	aws	aws	NNP
cord-009417-458rrhcm	667	12	,	,	,
cord-009417-458rrhcm	667	13	the	the	DT
cord-009417-458rrhcm	667	14	overall	overall	JJ
cord-009417-458rrhcm	667	15	success	success	NN
cord-009417-458rrhcm	667	16	of	of	IN
cord-009417-458rrhcm	667	17	this	this	DT
cord-009417-458rrhcm	667	18	therapy	therapy	NN
cord-009417-458rrhcm	667	19	in	in	IN
cord-009417-458rrhcm	667	20	reducing	reduce	VBG
cord-009417-458rrhcm	667	21	transfusion	transfusion	NN
cord-009417-458rrhcm	667	22	has	have	VBZ
cord-009417-458rrhcm	667	23	resulted	result	VBN
cord-009417-458rrhcm	667	24	in	in	IN
cord-009417-458rrhcm	667	25	its	-PRON-	PRP$
cord-009417-458rrhcm	667	26	wide	wide	JJ
cord-009417-458rrhcm	667	27	application	application	NN
cord-009417-458rrhcm	667	28	.	.	.
cord-009417-458rrhcm	668	1	148	148	CD
cord-009417-458rrhcm	668	2	Risks	risk	NNS
cord-009417-458rrhcm	668	3	include	include	VBP
cord-009417-458rrhcm	668	4	bacterial	bacterial	JJ
cord-009417-458rrhcm	668	5	contamination	contamination	NN
cord-009417-458rrhcm	668	6	,	,	,
cord-009417-458rrhcm	668	7	febrile	febrile	JJ
cord-009417-458rrhcm	668	8	reactions	reaction	NNS
cord-009417-458rrhcm	668	9	,	,	,
cord-009417-458rrhcm	668	10	triggering	trigger	VBG
cord-009417-458rrhcm	668	11	of	of	IN
cord-009417-458rrhcm	668	12	DIC	DIC	NNP
cord-009417-458rrhcm	668	13	,	,	,
cord-009417-458rrhcm	668	14	and	and	CC
cord-009417-458rrhcm	668	15	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	668	16	as	as	IN
cord-009417-458rrhcm	668	17	a	a	DT
cord-009417-458rrhcm	668	18	result	result	NN
cord-009417-458rrhcm	668	19	of	of	IN
cord-009417-458rrhcm	668	20	dilution	dilution	NN
cord-009417-458rrhcm	668	21	.	.	.
cord-009417-458rrhcm	669	1	When	when	WRB
cord-009417-458rrhcm	669	2	combined	combine	VBN
cord-009417-458rrhcm	669	3	with	with	IN
cord-009417-458rrhcm	669	4	acute	acute	JJ
cord-009417-458rrhcm	669	5	intraoperative	intraoperative	JJ
cord-009417-458rrhcm	669	6	hemodilution	hemodilution	NN
cord-009417-458rrhcm	669	7	,	,	,
cord-009417-458rrhcm	669	8	this	this	DT
cord-009417-458rrhcm	669	9	technology	technology	NN
cord-009417-458rrhcm	669	10	is	be	VBZ
cord-009417-458rrhcm	669	11	also	also	RB
cord-009417-458rrhcm	669	12	potentially	potentially	RB
cord-009417-458rrhcm	669	13	cost	cost	NN
cord-009417-458rrhcm	669	14	saving	saving	NN
cord-009417-458rrhcm	669	15	.	.	.
cord-009417-458rrhcm	670	1	149	149	CD
cord-009417-458rrhcm	671	1	The	the	DT
cord-009417-458rrhcm	671	2	word	word	NN
cord-009417-458rrhcm	671	3	apheresis	apheresis	NN
cord-009417-458rrhcm	671	4	is	be	VBZ
cord-009417-458rrhcm	671	5	derived	derive	VBN
cord-009417-458rrhcm	671	6	from	from	IN
cord-009417-458rrhcm	671	7	the	the	DT
cord-009417-458rrhcm	671	8	Greek	greek	JJ
cord-009417-458rrhcm	671	9	aphairein	aphairein	NN
cord-009417-458rrhcm	671	10	,	,	,
cord-009417-458rrhcm	671	11	"	"	''
cord-009417-458rrhcm	671	12	to	to	TO
cord-009417-458rrhcm	671	13	take	take	VB
cord-009417-458rrhcm	671	14	away	away	RB
cord-009417-458rrhcm	671	15	"	"	''
cord-009417-458rrhcm	671	16	;	;	:
cord-009417-458rrhcm	671	17	thus	thus	RB
cord-009417-458rrhcm	671	18	,	,	,
cord-009417-458rrhcm	671	19	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	671	20	hemapheresis	hemapheresis	NN
cord-009417-458rrhcm	671	21	is	be	VBZ
cord-009417-458rrhcm	671	22	performed	perform	VBN
cord-009417-458rrhcm	671	23	to	to	TO
cord-009417-458rrhcm	671	24	remove	remove	VB
cord-009417-458rrhcm	671	25	unwanted	unwanted	JJ
cord-009417-458rrhcm	671	26	plasma	plasma	NN
cord-009417-458rrhcm	671	27	constituents	constituent	NNS
cord-009417-458rrhcm	671	28	(	(	-LRB-
cord-009417-458rrhcm	671	29	plasmapheresis	plasmapheresis	NN
cord-009417-458rrhcm	671	30	)	)	-RRB-
cord-009417-458rrhcm	671	31	or	or	CC
cord-009417-458rrhcm	671	32	blood	blood	NN
cord-009417-458rrhcm	671	33	cells	cell	NNS
cord-009417-458rrhcm	671	34	(	(	-LRB-
cord-009417-458rrhcm	671	35	cytapheresis	cytapheresis	NNP
cord-009417-458rrhcm	671	36	)	)	-RRB-
cord-009417-458rrhcm	671	37	.	.	.
cord-009417-458rrhcm	672	1	Automated	automated	JJ
cord-009417-458rrhcm	672	2	cell	cell	NN
cord-009417-458rrhcm	672	3	separators	separator	NNS
cord-009417-458rrhcm	672	4	use	use	VBP
cord-009417-458rrhcm	672	5	centrifugation	centrifugation	NN
cord-009417-458rrhcm	672	6	or	or	CC
cord-009417-458rrhcm	672	7	membrane	membrane	NN
cord-009417-458rrhcm	672	8	fi	fi	IN
cord-009417-458rrhcm	672	9	ltration	ltration	NN
cord-009417-458rrhcm	672	10	to	to	TO
cord-009417-458rrhcm	672	11	remove	remove	VB
cord-009417-458rrhcm	672	12	and	and	CC
cord-009417-458rrhcm	672	13	concentrate	concentrate	VB
cord-009417-458rrhcm	672	14	the	the	DT
cord-009417-458rrhcm	672	15	selected	select	VBN
cord-009417-458rrhcm	672	16	blood	blood	NN
cord-009417-458rrhcm	672	17	element	element	NN
cord-009417-458rrhcm	672	18	.	.	.
cord-009417-458rrhcm	673	1	Many	many	JJ
cord-009417-458rrhcm	673	2	of	of	IN
cord-009417-458rrhcm	673	3	the	the	DT
cord-009417-458rrhcm	673	4	same	same	JJ
cord-009417-458rrhcm	673	5	devices	device	NNS
cord-009417-458rrhcm	673	6	used	use	VBD
cord-009417-458rrhcm	673	7	to	to	TO
cord-009417-458rrhcm	673	8	prepare	prepare	VB
cord-009417-458rrhcm	673	9	apheresis	apheresis	NN
cord-009417-458rrhcm	673	10	blood	blood	NN
cord-009417-458rrhcm	673	11	components	component	NNS
cord-009417-458rrhcm	673	12	for	for	IN
cord-009417-458rrhcm	673	13	transfusion	transfusion	NN
cord-009417-458rrhcm	673	14	are	be	VBP
cord-009417-458rrhcm	673	15	used	use	VBN
cord-009417-458rrhcm	673	16	to	to	TO
cord-009417-458rrhcm	673	17	perform	perform	VB
cord-009417-458rrhcm	673	18	patient	patient	JJ
cord-009417-458rrhcm	673	19	procedures	procedure	NNS
cord-009417-458rrhcm	673	20	,	,	,
cord-009417-458rrhcm	673	21	so	so	RB
cord-009417-458rrhcm	673	22	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	673	23	apheresis	apheresis	NN
cord-009417-458rrhcm	673	24	is	be	VBZ
cord-009417-458rrhcm	673	25	often	often	RB
cord-009417-458rrhcm	673	26	administered	administer	VBN
cord-009417-458rrhcm	673	27	under	under	IN
cord-009417-458rrhcm	673	28	the	the	DT
cord-009417-458rrhcm	673	29	auspices	auspex	NNS
cord-009417-458rrhcm	673	30	of	of	IN
cord-009417-458rrhcm	673	31	the	the	DT
cord-009417-458rrhcm	673	32	transfusion	transfusion	NN
cord-009417-458rrhcm	673	33	medicine	medicine	NN
cord-009417-458rrhcm	673	34	service	service	NN
cord-009417-458rrhcm	673	35	.	.	.
cord-009417-458rrhcm	674	1	Rapid	rapid	JJ
cord-009417-458rrhcm	674	2	removal	removal	NN
cord-009417-458rrhcm	674	3	of	of	IN
cord-009417-458rrhcm	674	4	plasma	plasma	NN
cord-009417-458rrhcm	674	5	or	or	CC
cord-009417-458rrhcm	674	6	cells	cell	NNS
cord-009417-458rrhcm	675	1	may	may	MD
cord-009417-458rrhcm	675	2	fi	fi	VB
cord-009417-458rrhcm	676	1	nd	nd	NNP
cord-009417-458rrhcm	677	1	several	several	JJ
cord-009417-458rrhcm	677	2	applications	application	NNS
cord-009417-458rrhcm	677	3	in	in	IN
cord-009417-458rrhcm	677	4	intensive	intensive	JJ
cord-009417-458rrhcm	677	5	care	care	NN
cord-009417-458rrhcm	677	6	practice	practice	NN
cord-009417-458rrhcm	677	7	(	(	-LRB-
cord-009417-458rrhcm	677	8	Box	Box	NNP
cord-009417-458rrhcm	677	9	80	80	CD
cord-009417-458rrhcm	677	10	-	-	SYM
cord-009417-458rrhcm	677	11	2	2	CD
cord-009417-458rrhcm	677	12	)	)	-RRB-
cord-009417-458rrhcm	677	13	.	.	.
cord-009417-458rrhcm	678	1	The	the	DT
cord-009417-458rrhcm	678	2	goal	goal	NN
cord-009417-458rrhcm	678	3	of	of	IN
cord-009417-458rrhcm	678	4	plasmapheresis	plasmapheresis	NN
cord-009417-458rrhcm	678	5	,	,	,
cord-009417-458rrhcm	678	6	or	or	CC
cord-009417-458rrhcm	678	7	plasma	plasma	NN
cord-009417-458rrhcm	678	8	exchange	exchange	NN
cord-009417-458rrhcm	678	9	(	(	-LRB-
cord-009417-458rrhcm	678	10	PE	PE	NNP
cord-009417-458rrhcm	678	11	)	)	-RRB-
cord-009417-458rrhcm	678	12	,	,	,
cord-009417-458rrhcm	678	13	is	be	VBZ
cord-009417-458rrhcm	678	14	to	to	TO
cord-009417-458rrhcm	678	15	remove	remove	VB
cord-009417-458rrhcm	678	16	or	or	CC
cord-009417-458rrhcm	678	17	reduce	reduce	VB
cord-009417-458rrhcm	678	18	the	the	DT
cord-009417-458rrhcm	678	19	levels	level	NNS
cord-009417-458rrhcm	678	20	of	of	IN
cord-009417-458rrhcm	678	21	an	an	DT
cord-009417-458rrhcm	678	22	undesirable	undesirable	JJ
cord-009417-458rrhcm	678	23	plasma	plasma	NN
cord-009417-458rrhcm	678	24	constituent	constituent	NN
cord-009417-458rrhcm	678	25	or	or	CC
cord-009417-458rrhcm	678	26	,	,	,
cord-009417-458rrhcm	678	27	alternatively	alternatively	RB
cord-009417-458rrhcm	678	28	,	,	,
cord-009417-458rrhcm	678	29	by	by	IN
cord-009417-458rrhcm	678	30	means	mean	NNS
cord-009417-458rrhcm	678	31	of	of	IN
cord-009417-458rrhcm	678	32	plasma	plasma	NN
cord-009417-458rrhcm	678	33	replacement	replacement	NN
cord-009417-458rrhcm	678	34	,	,	,
cord-009417-458rrhcm	678	35	to	to	TO
cord-009417-458rrhcm	678	36	supply	supply	VB
cord-009417-458rrhcm	678	37	a	a	DT
cord-009417-458rrhcm	678	38	missing	miss	VBG
cord-009417-458rrhcm	678	39	substance	substance	NN
cord-009417-458rrhcm	678	40	.	.	.
cord-009417-458rrhcm	679	1	The	the	DT
cord-009417-458rrhcm	679	2	agent	agent	NN
cord-009417-458rrhcm	679	3	to	to	TO
cord-009417-458rrhcm	679	4	be	be	VB
cord-009417-458rrhcm	679	5	removed	remove	VBN
cord-009417-458rrhcm	679	6	by	by	IN
cord-009417-458rrhcm	679	7	PE	PE	NNP
cord-009417-458rrhcm	679	8	is	be	VBZ
cord-009417-458rrhcm	679	9	thought	think	VBN
cord-009417-458rrhcm	679	10	to	to	TO
cord-009417-458rrhcm	679	11	be	be	VB
cord-009417-458rrhcm	679	12	an	an	DT
cord-009417-458rrhcm	679	13	autoantibody	autoantibody	NN
cord-009417-458rrhcm	679	14	in	in	IN
cord-009417-458rrhcm	679	15	some	some	DT
cord-009417-458rrhcm	679	16	of	of	IN
cord-009417-458rrhcm	679	17	the	the	DT
cord-009417-458rrhcm	679	18	neurologic	neurologic	JJ
cord-009417-458rrhcm	679	19	,	,	,
cord-009417-458rrhcm	679	20	renal	renal	JJ
cord-009417-458rrhcm	679	21	,	,	,
cord-009417-458rrhcm	679	22	or	or	CC
cord-009417-458rrhcm	679	23	hematologic	hematologic	JJ
cord-009417-458rrhcm	679	24	conditions	condition	NNS
cord-009417-458rrhcm	679	25	treated	treat	VBN
cord-009417-458rrhcm	679	26	in	in	IN
cord-009417-458rrhcm	679	27	this	this	DT
cord-009417-458rrhcm	679	28	manner	manner	NN
cord-009417-458rrhcm	679	29	.	.	.
cord-009417-458rrhcm	680	1	150	150	CD
cord-009417-458rrhcm	680	2	Immunomodulation	Immunomodulation	NNP
cord-009417-458rrhcm	680	3	by	by	IN
cord-009417-458rrhcm	680	4	PE	PE	NNP
cord-009417-458rrhcm	680	5	is	be	VBZ
cord-009417-458rrhcm	680	6	another	another	DT
cord-009417-458rrhcm	680	7	explanation	explanation	NN
cord-009417-458rrhcm	680	8	for	for	IN
cord-009417-458rrhcm	680	9	its	-PRON-	PRP$
cord-009417-458rrhcm	680	10	effect	effect	NN
cord-009417-458rrhcm	680	11	,	,	,
cord-009417-458rrhcm	680	12	a	a	DT
cord-009417-458rrhcm	680	13	theory	theory	NN
cord-009417-458rrhcm	680	14	indirectly	indirectly	RB
cord-009417-458rrhcm	680	15	supported	support	VBN
cord-009417-458rrhcm	680	16	by	by	IN
cord-009417-458rrhcm	680	17	the	the	DT
cord-009417-458rrhcm	680	18	equivalent	equivalent	JJ
cord-009417-458rrhcm	680	19	effi	effi	NNP
cord-009417-458rrhcm	680	20	cacy	cacy	NN
cord-009417-458rrhcm	680	21	of	of	IN
cord-009417-458rrhcm	680	22	IVIG	IVIG	NNP
cord-009417-458rrhcm	680	23	therapy	therapy	NN
cord-009417-458rrhcm	680	24	for	for	IN
cord-009417-458rrhcm	680	25	several	several	JJ
cord-009417-458rrhcm	680	26	of	of	IN
cord-009417-458rrhcm	680	27	these	these	DT
cord-009417-458rrhcm	680	28	disorders	disorder	NNS
cord-009417-458rrhcm	680	29	.	.	.
cord-009417-458rrhcm	681	1	151	151	CD
cord-009417-458rrhcm	681	2	PE	pe	NN
cord-009417-458rrhcm	681	3	for	for	IN
cord-009417-458rrhcm	681	4	the	the	DT
cord-009417-458rrhcm	681	5	amelioration	amelioration	NN
cord-009417-458rrhcm	681	6	of	of	IN
cord-009417-458rrhcm	681	7	hyperviscosity	hyperviscosity	NN
cord-009417-458rrhcm	681	8	from	from	IN
cord-009417-458rrhcm	681	9	either	either	CC
cord-009417-458rrhcm	681	10	excess	excess	JJ
cord-009417-458rrhcm	681	11	IgM	igm	NN
cord-009417-458rrhcm	681	12	in	in	IN
cord-009417-458rrhcm	681	13	Waldenström	Waldenström	NNP
cord-009417-458rrhcm	681	14	's	's	POS
cord-009417-458rrhcm	681	15	macroglobulinemia	macroglobulinemia	NN
cord-009417-458rrhcm	681	16	or	or	CC
cord-009417-458rrhcm	681	17	excess	excess	JJ
cord-009417-458rrhcm	681	18	Ig	Ig	NNP
cord-009417-458rrhcm	681	19	in	in	IN
cord-009417-458rrhcm	681	20	multiple	multiple	JJ
cord-009417-458rrhcm	681	21	myeloma	myeloma	NN
cord-009417-458rrhcm	681	22	is	be	VBZ
cord-009417-458rrhcm	681	23	an	an	DT
cord-009417-458rrhcm	681	24	effective	effective	JJ
cord-009417-458rrhcm	681	25	temporizing	temporizing	JJ
cord-009417-458rrhcm	681	26	measure	measure	NN
cord-009417-458rrhcm	681	27	in	in	IN
cord-009417-458rrhcm	681	28	the	the	DT
cord-009417-458rrhcm	681	29	treatment	treatment	NN
cord-009417-458rrhcm	681	30	of	of	IN
cord-009417-458rrhcm	681	31	these	these	DT
cord-009417-458rrhcm	681	32	conditions	condition	NNS
cord-009417-458rrhcm	681	33	.	.	.
cord-009417-458rrhcm	682	1	152	152	CD
cord-009417-458rrhcm	683	1	Plasmapheresis	Plasmapheresis	NNP
cord-009417-458rrhcm	683	2	with	with	IN
cord-009417-458rrhcm	683	3	PE	PE	NNP
cord-009417-458rrhcm	683	4	is	be	VBZ
cord-009417-458rrhcm	683	5	the	the	DT
cord-009417-458rrhcm	683	6	standard	standard	JJ
cord-009417-458rrhcm	683	7	therapy	therapy	NN
cord-009417-458rrhcm	683	8	for	for	IN
cord-009417-458rrhcm	683	9	TTP	TTP	NNP
cord-009417-458rrhcm	683	10	.	.	.
cord-009417-458rrhcm	684	1	153	153	CD
cord-009417-458rrhcm	685	1	Unfortunately	unfortunately	RB
cord-009417-458rrhcm	685	2	,	,	,
cord-009417-458rrhcm	685	3	few	few	JJ
cord-009417-458rrhcm	685	4	controlled	control	VBN
cord-009417-458rrhcm	685	5	trials	trial	NNS
cord-009417-458rrhcm	685	6	of	of	IN
cord-009417-458rrhcm	685	7	PE	PE	NNP
cord-009417-458rrhcm	685	8	exist	exist	VBP
cord-009417-458rrhcm	685	9	,	,	,
cord-009417-458rrhcm	685	10	although	although	IN
cord-009417-458rrhcm	685	11	anecdotal	anecdotal	JJ
cord-009417-458rrhcm	685	12	reports	report	NNS
cord-009417-458rrhcm	685	13	abound	abound	VBP
cord-009417-458rrhcm	685	14	.	.	.
cord-009417-458rrhcm	686	1	PE	PE	NNP
cord-009417-458rrhcm	686	2	is	be	VBZ
cord-009417-458rrhcm	686	3	seldom	seldom	RB
cord-009417-458rrhcm	686	4	the	the	DT
cord-009417-458rrhcm	686	5	defi	defi	NNP
cord-009417-458rrhcm	686	6	nitive	nitive	JJ
cord-009417-458rrhcm	686	7	treatment	treatment	NN
cord-009417-458rrhcm	686	8	of	of	IN
cord-009417-458rrhcm	686	9	most	most	JJS
cord-009417-458rrhcm	686	10	of	of	IN
cord-009417-458rrhcm	686	11	these	these	DT
cord-009417-458rrhcm	686	12	conditions	condition	NNS
cord-009417-458rrhcm	686	13	and	and	CC
cord-009417-458rrhcm	686	14	is	be	VBZ
cord-009417-458rrhcm	686	15	used	use	VBN
cord-009417-458rrhcm	686	16	most	most	RBS
cord-009417-458rrhcm	686	17	appropriately	appropriately	RB
cord-009417-458rrhcm	686	18	as	as	IN
cord-009417-458rrhcm	686	19	a	a	DT
cord-009417-458rrhcm	686	20	short	short	JJ
cord-009417-458rrhcm	686	21	-	-	HYPH
cord-009417-458rrhcm	686	22	term	term	NN
cord-009417-458rrhcm	686	23	adjunct	adjunct	NN
cord-009417-458rrhcm	686	24	to	to	IN
cord-009417-458rrhcm	686	25	other	other	JJ
cord-009417-458rrhcm	686	26	medical	medical	JJ
cord-009417-458rrhcm	686	27	modalities	modality	NNS
cord-009417-458rrhcm	686	28	.	.	.
cord-009417-458rrhcm	687	1	The	the	DT
cord-009417-458rrhcm	687	2	kinetics	kinetic	NNS
cord-009417-458rrhcm	687	3	of	of	IN
cord-009417-458rrhcm	687	4	PE	PE	NNP
cord-009417-458rrhcm	687	5	predicts	predict	VBZ
cord-009417-458rrhcm	687	6	that	that	IN
cord-009417-458rrhcm	687	7	a	a	DT
cord-009417-458rrhcm	687	8	one	one	CD
cord-009417-458rrhcm	687	9	-	-	HYPH
cord-009417-458rrhcm	687	10	volume	volume	NN
cord-009417-458rrhcm	687	11	exchange	exchange	NN
cord-009417-458rrhcm	687	12	removes	remove	VBZ
cord-009417-458rrhcm	687	13	65	65	CD
cord-009417-458rrhcm	687	14	%	%	NN
cord-009417-458rrhcm	687	15	of	of	IN
cord-009417-458rrhcm	687	16	a	a	DT
cord-009417-458rrhcm	687	17	given	give	VBN
cord-009417-458rrhcm	687	18	plasma	plasma	NN
cord-009417-458rrhcm	687	19	constituent	constituent	NN
cord-009417-458rrhcm	687	20	if	if	IN
cord-009417-458rrhcm	687	21	the	the	DT
cord-009417-458rrhcm	687	22	blood	blood	NN
cord-009417-458rrhcm	687	23	volume	volume	NN
cord-009417-458rrhcm	687	24	does	do	VBZ
cord-009417-458rrhcm	687	25	not	not	RB
cord-009417-458rrhcm	687	26	change	change	VB
cord-009417-458rrhcm	687	27	or	or	CC
cord-009417-458rrhcm	687	28	additional	additional	JJ
cord-009417-458rrhcm	687	29	synthesis	synthesis	NN
cord-009417-458rrhcm	687	30	or	or	CC
cord-009417-458rrhcm	687	31	mobilization	mobilization	NN
cord-009417-458rrhcm	687	32	of	of	IN
cord-009417-458rrhcm	687	33	the	the	DT
cord-009417-458rrhcm	687	34	substance	substance	NN
cord-009417-458rrhcm	687	35	does	do	VBZ
cord-009417-458rrhcm	687	36	not	not	RB
cord-009417-458rrhcm	687	37	occur	occur	VB
cord-009417-458rrhcm	687	38	.	.	.
cord-009417-458rrhcm	688	1	Two	two	CD
cord-009417-458rrhcm	688	2	or	or	CC
cord-009417-458rrhcm	688	3	three	three	CD
cord-009417-458rrhcm	688	4	volume	volume	NN
cord-009417-458rrhcm	688	5	exchanges	exchange	NNS
cord-009417-458rrhcm	688	6	remove	remove	VBP
cord-009417-458rrhcm	688	7	87	87	CD
cord-009417-458rrhcm	688	8	%	%	NN
cord-009417-458rrhcm	688	9	and	and	CC
cord-009417-458rrhcm	688	10	95	95	CD
cord-009417-458rrhcm	688	11	%	%	NN
cord-009417-458rrhcm	688	12	,	,	,
cord-009417-458rrhcm	688	13	respectively	respectively	RB
cord-009417-458rrhcm	688	14	.	.	.
cord-009417-458rrhcm	689	1	Highly	highly	RB
cord-009417-458rrhcm	689	2	protein	protein	NN
cord-009417-458rrhcm	689	3	-	-	HYPH
cord-009417-458rrhcm	689	4	bound	bind	VBN
cord-009417-458rrhcm	689	5	,	,	,
cord-009417-458rrhcm	689	6	intravascularly	intravascularly	RB
cord-009417-458rrhcm	689	7	concentrated	concentrated	JJ
cord-009417-458rrhcm	689	8	substances	substance	NNS
cord-009417-458rrhcm	689	9	are	be	VBP
cord-009417-458rrhcm	689	10	most	most	RBS
cord-009417-458rrhcm	689	11	effi	effi	NNP
cord-009417-458rrhcm	689	12	ciently	ciently	RB
cord-009417-458rrhcm	689	13	removed	remove	VBN
cord-009417-458rrhcm	689	14	,	,	,
cord-009417-458rrhcm	689	15	whereas	whereas	IN
cord-009417-458rrhcm	689	16	substances	substance	NNS
cord-009417-458rrhcm	689	17	with	with	IN
cord-009417-458rrhcm	689	18	a	a	DT
cord-009417-458rrhcm	689	19	large	large	JJ
cord-009417-458rrhcm	689	20	volume	volume	NN
cord-009417-458rrhcm	689	21	of	of	IN
cord-009417-458rrhcm	689	22	distribution	distribution	NN
cord-009417-458rrhcm	689	23	such	such	JJ
cord-009417-458rrhcm	689	24	as	as	IN
cord-009417-458rrhcm	689	25	IgG	IgG	NNP
cord-009417-458rrhcm	689	26	,	,	,
cord-009417-458rrhcm	689	27	active	active	JJ
cord-009417-458rrhcm	689	28	synthesis	synthesis	NN
cord-009417-458rrhcm	689	29	,	,	,
cord-009417-458rrhcm	689	30	or	or	CC
cord-009417-458rrhcm	689	31	large	large	JJ
cord-009417-458rrhcm	689	32	extravascular	extravascular	JJ
cord-009417-458rrhcm	689	33	stores	store	NNS
cord-009417-458rrhcm	689	34	are	be	VBP
cord-009417-458rrhcm	689	35	removed	remove	VBN
cord-009417-458rrhcm	689	36	at	at	IN
cord-009417-458rrhcm	689	37	less	less	JJR
cord-009417-458rrhcm	689	38	than	than	IN
cord-009417-458rrhcm	689	39	predicted	predict	VBN
cord-009417-458rrhcm	689	40	rates	rate	NNS
cord-009417-458rrhcm	689	41	.	.	.
cord-009417-458rrhcm	690	1	The	the	DT
cord-009417-458rrhcm	690	2	usual	usual	JJ
cord-009417-458rrhcm	690	3	short	short	JJ
cord-009417-458rrhcm	690	4	-	-	HYPH
cord-009417-458rrhcm	690	5	term	term	NN
cord-009417-458rrhcm	690	6	intense	intense	JJ
cord-009417-458rrhcm	690	7	course	course	NN
cord-009417-458rrhcm	690	8	of	of	IN
cord-009417-458rrhcm	690	9	PE	PE	NNP
cord-009417-458rrhcm	690	10	schedules	schedule	NNS
cord-009417-458rrhcm	690	11	fi	fi	NNP
cord-009417-458rrhcm	690	12	ve	ve	VBD
cord-009417-458rrhcm	690	13	one	one	CD
cord-009417-458rrhcm	690	14	-	-	HYPH
cord-009417-458rrhcm	690	15	volume	volume	NN
cord-009417-458rrhcm	690	16	exchanges	exchange	NNS
cord-009417-458rrhcm	690	17	(	(	-LRB-
cord-009417-458rrhcm	690	18	approximately	approximately	RB
cord-009417-458rrhcm	690	19	3	3	CD
cord-009417-458rrhcm	690	20	L	l	NN
cord-009417-458rrhcm	690	21	in	in	IN
cord-009417-458rrhcm	690	22	normal	normal	JJ
cord-009417-458rrhcm	690	23	-	-	HYPH
cord-009417-458rrhcm	690	24	sized	sized	JJ
cord-009417-458rrhcm	690	25	adults	adult	NNS
cord-009417-458rrhcm	690	26	)	)	-RRB-
cord-009417-458rrhcm	690	27	over	over	IN
cord-009417-458rrhcm	690	28	a	a	DT
cord-009417-458rrhcm	690	29	7-day	7-day	JJ
cord-009417-458rrhcm	690	30	period	period	NN
cord-009417-458rrhcm	690	31	.	.	.
cord-009417-458rrhcm	691	1	The	the	DT
cord-009417-458rrhcm	691	2	appropriate	appropriate	JJ
cord-009417-458rrhcm	691	3	replacement	replacement	NN
cord-009417-458rrhcm	691	4	fl	fl	NNP
cord-009417-458rrhcm	691	5	uid	uid	NN
cord-009417-458rrhcm	691	6	in	in	IN
cord-009417-458rrhcm	691	7	most	most	JJS
cord-009417-458rrhcm	691	8	conditions	condition	NNS
cord-009417-458rrhcm	691	9	is	be	VBZ
cord-009417-458rrhcm	691	10	an	an	DT
cord-009417-458rrhcm	691	11	albumin	albumin	NN
cord-009417-458rrhcm	691	12	-	-	HYPH
cord-009417-458rrhcm	691	13	saline	saline	NN
cord-009417-458rrhcm	691	14	mixture	mixture	NN
cord-009417-458rrhcm	691	15	,	,	,
cord-009417-458rrhcm	691	16	which	which	WDT
cord-009417-458rrhcm	691	17	provides	provide	VBZ
cord-009417-458rrhcm	691	18	oncotic	oncotic	JJ
cord-009417-458rrhcm	691	19	support	support	NN
cord-009417-458rrhcm	691	20	without	without	IN
cord-009417-458rrhcm	691	21	the	the	DT
cord-009417-458rrhcm	691	22	risk	risk	NN
cord-009417-458rrhcm	691	23	of	of	IN
cord-009417-458rrhcm	691	24	disease	disease	NN
cord-009417-458rrhcm	691	25	transmission	transmission	NN
cord-009417-458rrhcm	691	26	borne	bear	VBN
cord-009417-458rrhcm	691	27	by	by	IN
cord-009417-458rrhcm	691	28	FFP	FFP	NNP
cord-009417-458rrhcm	691	29	.	.	.
cord-009417-458rrhcm	692	1	PE	PE	NNP
cord-009417-458rrhcm	692	2	in	in	IN
cord-009417-458rrhcm	692	3	patients	patient	NNS
cord-009417-458rrhcm	692	4	with	with	IN
cord-009417-458rrhcm	692	5	TTP	TTP	NNP
cord-009417-458rrhcm	692	6	uses	use	VBZ
cord-009417-458rrhcm	692	7	replacement	replacement	NN
cord-009417-458rrhcm	692	8	with	with	IN
cord-009417-458rrhcm	692	9	FFP	FFP	NNP
cord-009417-458rrhcm	692	10	to	to	TO
cord-009417-458rrhcm	692	11	supply	supply	VB
cord-009417-458rrhcm	692	12	the	the	DT
cord-009417-458rrhcm	692	13	plasma	plasma	NN
cord-009417-458rrhcm	692	14	protease	protease	NN
cord-009417-458rrhcm	692	15	that	that	WDT
cord-009417-458rrhcm	692	16	is	be	VBZ
cord-009417-458rrhcm	692	17	consumed	consume	VBN
cord-009417-458rrhcm	692	18	during	during	IN
cord-009417-458rrhcm	692	19	the	the	DT
cord-009417-458rrhcm	692	20	disease	disease	NN
cord-009417-458rrhcm	692	21	.	.	.
cord-009417-458rrhcm	693	1	Side	side	JJ
cord-009417-458rrhcm	693	2	effects	effect	NNS
cord-009417-458rrhcm	693	3	of	of	IN
cord-009417-458rrhcm	693	4	PE	PE	NNP
cord-009417-458rrhcm	693	5	are	be	VBP
cord-009417-458rrhcm	693	6	relatively	relatively	RB
cord-009417-458rrhcm	693	7	common	common	JJ
cord-009417-458rrhcm	693	8	(	(	-LRB-
cord-009417-458rrhcm	693	9	10	10	CD
cord-009417-458rrhcm	693	10	%	%	NN
cord-009417-458rrhcm	693	11	to	to	TO
cord-009417-458rrhcm	693	12	30	30	CD
cord-009417-458rrhcm	693	13	%	%	NN
cord-009417-458rrhcm	693	14	of	of	IN
cord-009417-458rrhcm	693	15	procedures	procedure	NNS
cord-009417-458rrhcm	693	16	)	)	-RRB-
cord-009417-458rrhcm	693	17	but	but	CC
cord-009417-458rrhcm	693	18	generally	generally	RB
cord-009417-458rrhcm	693	19	minor	minor	JJ
cord-009417-458rrhcm	693	20	and	and	CC
cord-009417-458rrhcm	693	21	are	be	VBP
cord-009417-458rrhcm	693	22	related	relate	VBN
cord-009417-458rrhcm	693	23	to	to	IN
cord-009417-458rrhcm	693	24	vascular	vascular	JJ
cord-009417-458rrhcm	693	25	access	access	NN
cord-009417-458rrhcm	693	26	,	,	,
cord-009417-458rrhcm	693	27	temporary	temporary	JJ
cord-009417-458rrhcm	693	28	discomfort	discomfort	NN
cord-009417-458rrhcm	693	29	,	,	,
cord-009417-458rrhcm	693	30	or	or	CC
cord-009417-458rrhcm	693	31	vasomotor	vasomotor	NN
cord-009417-458rrhcm	693	32	symptoms	symptom	NNS
cord-009417-458rrhcm	693	33	.	.	.
cord-009417-458rrhcm	694	1	154	154	CD
cord-009417-458rrhcm	694	2	Patient	patient	JJ
cord-009417-458rrhcm	694	3	death	death	NN
cord-009417-458rrhcm	694	4	is	be	VBZ
cord-009417-458rrhcm	694	5	rarely	rarely	RB
cord-009417-458rrhcm	694	6	due	due	JJ
cord-009417-458rrhcm	694	7	to	to	IN
cord-009417-458rrhcm	694	8	the	the	DT
cord-009417-458rrhcm	694	9	procedure	procedure	NN
cord-009417-458rrhcm	694	10	itself	-PRON-	PRP
cord-009417-458rrhcm	694	11	but	but	CC
cord-009417-458rrhcm	694	12	is	be	VBZ
cord-009417-458rrhcm	694	13	largely	largely	RB
cord-009417-458rrhcm	694	14	of	of	IN
cord-009417-458rrhcm	694	15	cardiopulmonary	cardiopulmonary	JJ
cord-009417-458rrhcm	694	16	causes	cause	NNS
cord-009417-458rrhcm	694	17	.	.	.
cord-009417-458rrhcm	695	1	Plasma	plasma	NN
cord-009417-458rrhcm	695	2	proteins	protein	NNS
cord-009417-458rrhcm	695	3	such	such	JJ
cord-009417-458rrhcm	695	4	as	as	IN
cord-009417-458rrhcm	695	5	coagulation	coagulation	NN
cord-009417-458rrhcm	695	6	factors	factor	NNS
cord-009417-458rrhcm	695	7	,	,	,
cord-009417-458rrhcm	695	8	immunoglobulins	immunoglobulin	NNS
cord-009417-458rrhcm	695	9	,	,	,
cord-009417-458rrhcm	695	10	and	and	CC
cord-009417-458rrhcm	695	11	complement	complement	NN
cord-009417-458rrhcm	695	12	will	will	MD
cord-009417-458rrhcm	695	13	be	be	VB
cord-009417-458rrhcm	695	14	removed	remove	VBN
cord-009417-458rrhcm	695	15	by	by	IN
cord-009417-458rrhcm	695	16	PE	PE	NNP
cord-009417-458rrhcm	695	17	,	,	,
cord-009417-458rrhcm	695	18	and	and	CC
cord-009417-458rrhcm	695	19	laboratory	laboratory	NN
cord-009417-458rrhcm	695	20	test	test	NN
cord-009417-458rrhcm	695	21	results	result	NNS
cord-009417-458rrhcm	695	22	of	of	IN
cord-009417-458rrhcm	695	23	coagulation	coagulation	NN
cord-009417-458rrhcm	695	24	and	and	CC
cord-009417-458rrhcm	695	25	electrolytes	electrolyte	NNS
cord-009417-458rrhcm	695	26	may	may	MD
cord-009417-458rrhcm	695	27	be	be	VB
cord-009417-458rrhcm	695	28	deranged	deranged	JJ
cord-009417-458rrhcm	695	29	in	in	IN
cord-009417-458rrhcm	695	30	the	the	DT
cord-009417-458rrhcm	695	31	hours	hour	NNS
cord-009417-458rrhcm	695	32	after	after	IN
cord-009417-458rrhcm	695	33	PE	PE	NNP
cord-009417-458rrhcm	695	34	.	.	.
cord-009417-458rrhcm	696	1	Clinical	clinical	JJ
cord-009417-458rrhcm	696	2	bleeding	bleeding	NN
cord-009417-458rrhcm	696	3	is	be	VBZ
cord-009417-458rrhcm	696	4	rarely	rarely	RB
cord-009417-458rrhcm	696	5	observed	observe	VBN
cord-009417-458rrhcm	696	6	.	.	.
cord-009417-458rrhcm	697	1	Most	Most	JJS
cord-009417-458rrhcm	697	2	coagulation	coagulation	NN
cord-009417-458rrhcm	697	3	factors	factor	NNS
cord-009417-458rrhcm	697	4	do	do	VBP
cord-009417-458rrhcm	697	5	not	not	RB
cord-009417-458rrhcm	697	6	fall	fall	VB
cord-009417-458rrhcm	697	7	below	below	IN
cord-009417-458rrhcm	697	8	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	697	9	levels	level	NNS
cord-009417-458rrhcm	697	10	and	and	CC
cord-009417-458rrhcm	697	11	recover	recover	VB
cord-009417-458rrhcm	697	12	within	within	IN
cord-009417-458rrhcm	697	13	hours	hour	NNS
cord-009417-458rrhcm	697	14	,	,	,
cord-009417-458rrhcm	697	15	with	with	IN
cord-009417-458rrhcm	697	16	the	the	DT
cord-009417-458rrhcm	697	17	exception	exception	NN
cord-009417-458rrhcm	697	18	of	of	IN
cord-009417-458rrhcm	697	19	fi	fi	NNP
cord-009417-458rrhcm	697	20	brinogen	brinogen	NNP
cord-009417-458rrhcm	697	21	,	,	,
cord-009417-458rrhcm	697	22	which	which	WDT
cord-009417-458rrhcm	697	23	may	may	MD
cord-009417-458rrhcm	697	24	require	require	VB
cord-009417-458rrhcm	697	25	several	several	JJ
cord-009417-458rrhcm	697	26	days	day	NNS
cord-009417-458rrhcm	697	27	for	for	IN
cord-009417-458rrhcm	697	28	complete	complete	JJ
cord-009417-458rrhcm	697	29	replenishment	replenishment	NN
cord-009417-458rrhcm	697	30	.	.	.
cord-009417-458rrhcm	698	1	Leukapheresis	Leukapheresis	NNP
cord-009417-458rrhcm	698	2	may	may	MD
cord-009417-458rrhcm	698	3	be	be	VB
cord-009417-458rrhcm	698	4	required	require	VBN
cord-009417-458rrhcm	698	5	to	to	TO
cord-009417-458rrhcm	698	6	urgently	urgently	RB
cord-009417-458rrhcm	698	7	reduce	reduce	VB
cord-009417-458rrhcm	698	8	the	the	DT
cord-009417-458rrhcm	698	9	WBC	WBC	NNP
cord-009417-458rrhcm	698	10	count	count	NN
cord-009417-458rrhcm	698	11	in	in	IN
cord-009417-458rrhcm	698	12	patients	patient	NNS
cord-009417-458rrhcm	698	13	with	with	IN
cord-009417-458rrhcm	698	14	acute	acute	JJ
cord-009417-458rrhcm	698	15	myeloid	myeloid	NN
cord-009417-458rrhcm	698	16	or	or	CC
cord-009417-458rrhcm	698	17	lymphoblastic	lymphoblastic	JJ
cord-009417-458rrhcm	698	18	leukemia	leukemia	NN
cord-009417-458rrhcm	698	19	or	or	CC
cord-009417-458rrhcm	698	20	chronic	chronic	JJ
cord-009417-458rrhcm	698	21	myelogenous	myelogenous	NN
cord-009417-458rrhcm	698	22	leukemia	leukemia	NN
cord-009417-458rrhcm	698	23	with	with	IN
cord-009417-458rrhcm	698	24	peripheral	peripheral	JJ
cord-009417-458rrhcm	698	25	counts	count	NNS
cord-009417-458rrhcm	698	26	of	of	IN
cord-009417-458rrhcm	698	27	100	100	CD
cord-009417-458rrhcm	698	28	×	×	NN
cord-009417-458rrhcm	698	29	10	10	CD
cord-009417-458rrhcm	698	30	9	9	CD
cord-009417-458rrhcm	698	31	/L	/L	,
cord-009417-458rrhcm	698	32	or	or	CC
cord-009417-458rrhcm	698	33	greater	great	JJR
cord-009417-458rrhcm	698	34	.	.	.
cord-009417-458rrhcm	699	1	Each	each	DT
cord-009417-458rrhcm	699	2	procedure	procedure	NN
cord-009417-458rrhcm	699	3	is	be	VBZ
cord-009417-458rrhcm	699	4	expected	expect	VBN
cord-009417-458rrhcm	699	5	to	to	TO
cord-009417-458rrhcm	699	6	drop	drop	VB
cord-009417-458rrhcm	699	7	the	the	DT
cord-009417-458rrhcm	699	8	count	count	NN
cord-009417-458rrhcm	699	9	by	by	IN
cord-009417-458rrhcm	699	10	a	a	DT
cord-009417-458rrhcm	699	11	third	third	NN
cord-009417-458rrhcm	699	12	,	,	,
cord-009417-458rrhcm	699	13	but	but	CC
cord-009417-458rrhcm	699	14	the	the	DT
cord-009417-458rrhcm	699	15	effect	effect	NN
cord-009417-458rrhcm	699	16	is	be	VBZ
cord-009417-458rrhcm	699	17	short	short	RB
cord-009417-458rrhcm	699	18	lived	live	VBN
cord-009417-458rrhcm	699	19	.	.	.
cord-009417-458rrhcm	700	1	Leukapheresis	Leukapheresis	NNP
cord-009417-458rrhcm	700	2	should	should	MD
cord-009417-458rrhcm	700	3	be	be	VB
cord-009417-458rrhcm	700	4	reserved	reserve	VBN
cord-009417-458rrhcm	700	5	for	for	IN
cord-009417-458rrhcm	700	6	use	use	NN
cord-009417-458rrhcm	700	7	only	only	RB
cord-009417-458rrhcm	700	8	as	as	IN
cord-009417-458rrhcm	700	9	an	an	DT
cord-009417-458rrhcm	700	10	adjunct	adjunct	NN
cord-009417-458rrhcm	700	11	to	to	IN
cord-009417-458rrhcm	700	12	chemotherapy	chemotherapy	NN
cord-009417-458rrhcm	700	13	in	in	IN
cord-009417-458rrhcm	700	14	patients	patient	NNS
cord-009417-458rrhcm	700	15	with	with	IN
cord-009417-458rrhcm	700	16	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	700	17	or	or	CC
cord-009417-458rrhcm	700	18	cerebral	cerebral	JJ
cord-009417-458rrhcm	700	19	leukostasis	leukostasi	NNS
cord-009417-458rrhcm	700	20	or	or	CC
cord-009417-458rrhcm	700	21	for	for	IN
cord-009417-458rrhcm	700	22	cytoreduction	cytoreduction	NN
cord-009417-458rrhcm	700	23	before	before	IN
cord-009417-458rrhcm	700	24	chemotherapy	chemotherapy	NN
cord-009417-458rrhcm	700	25	in	in	IN
cord-009417-458rrhcm	700	26	patients	patient	NNS
cord-009417-458rrhcm	700	27	at	at	IN
cord-009417-458rrhcm	700	28	risk	risk	NN
cord-009417-458rrhcm	700	29	for	for	IN
cord-009417-458rrhcm	700	30	severe	severe	JJ
cord-009417-458rrhcm	700	31	tumor	tumor	NN
cord-009417-458rrhcm	700	32	lysis	lysis	NN
cord-009417-458rrhcm	700	33	syndrome	syndrome	NN
cord-009417-458rrhcm	700	34	.	.	.
cord-009417-458rrhcm	701	1	Plateletpheresis	Plateletpheresis	NNP
cord-009417-458rrhcm	701	2	may	may	MD
cord-009417-458rrhcm	701	3	be	be	VB
cord-009417-458rrhcm	701	4	benefi	benefi	NNP
cord-009417-458rrhcm	701	5	cial	cial	JJ
cord-009417-458rrhcm	701	6	as	as	IN
cord-009417-458rrhcm	701	7	short	short	JJ
cord-009417-458rrhcm	701	8	-	-	HYPH
cord-009417-458rrhcm	701	9	term	term	NN
cord-009417-458rrhcm	701	10	therapy	therapy	NN
cord-009417-458rrhcm	701	11	in	in	IN
cord-009417-458rrhcm	701	12	patients	patient	NNS
cord-009417-458rrhcm	701	13	with	with	IN
cord-009417-458rrhcm	701	14	symptomatic	symptomatic	JJ
cord-009417-458rrhcm	701	15	thrombocythemia	thrombocythemia	NN
cord-009417-458rrhcm	701	16	manifested	manifest	VBD
cord-009417-458rrhcm	701	17	as	as	IN
cord-009417-458rrhcm	701	18	cerebral	cerebral	JJ
cord-009417-458rrhcm	701	19	or	or	CC
cord-009417-458rrhcm	701	20	myocardial	myocardial	JJ
cord-009417-458rrhcm	701	21	ischemia	ischemia	NN
cord-009417-458rrhcm	701	22	,	,	,
cord-009417-458rrhcm	701	23	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	701	24	emboli	emboli	NN
cord-009417-458rrhcm	701	25	,	,	,
cord-009417-458rrhcm	701	26	or	or	CC
cord-009417-458rrhcm	701	27	gastrointestinal	gastrointestinal	JJ
cord-009417-458rrhcm	701	28	bleeding	bleeding	NN
cord-009417-458rrhcm	701	29	.	.	.
cord-009417-458rrhcm	702	1	Each	each	DT
cord-009417-458rrhcm	702	2	procedure	procedure	NN
cord-009417-458rrhcm	702	3	should	should	MD
cord-009417-458rrhcm	702	4	effect	effect	VB
cord-009417-458rrhcm	702	5	a	a	DT
cord-009417-458rrhcm	702	6	50	50	CD
cord-009417-458rrhcm	702	7	%	%	NN
cord-009417-458rrhcm	702	8	reduction	reduction	NN
cord-009417-458rrhcm	702	9	in	in	IN
cord-009417-458rrhcm	702	10	the	the	DT
cord-009417-458rrhcm	702	11	platelet	platelet	NN
cord-009417-458rrhcm	702	12	count	count	NN
cord-009417-458rrhcm	702	13	.	.	.
cord-009417-458rrhcm	703	1	Cytotoxic	cytotoxic	JJ
cord-009417-458rrhcm	703	2	therapy	therapy	NN
cord-009417-458rrhcm	703	3	should	should	MD
cord-009417-458rrhcm	703	4	be	be	VB
cord-009417-458rrhcm	703	5	started	start	VBN
cord-009417-458rrhcm	703	6	concomitantly	concomitantly	RB
cord-009417-458rrhcm	703	7	as	as	IN
cord-009417-458rrhcm	703	8	the	the	DT
cord-009417-458rrhcm	703	9	defi	defi	NNP
cord-009417-458rrhcm	703	10	nitive	nitive	NNP
cord-009417-458rrhcm	703	11	treatment	treatment	NN
cord-009417-458rrhcm	703	12	.	.	.
cord-009417-458rrhcm	704	1	Litigation	litigation	NN
cord-009417-458rrhcm	704	2	related	relate	VBN
cord-009417-458rrhcm	704	3	to	to	IN
cord-009417-458rrhcm	704	4	blood	blood	NN
cord-009417-458rrhcm	704	5	transfusion	transfusion	NN
cord-009417-458rrhcm	704	6	has	have	VBZ
cord-009417-458rrhcm	704	7	become	become	VBN
cord-009417-458rrhcm	704	8	prominent	prominent	JJ
cord-009417-458rrhcm	704	9	,	,	,
cord-009417-458rrhcm	704	10	particularly	particularly	RB
cord-009417-458rrhcm	704	11	after	after	IN
cord-009417-458rrhcm	704	12	the	the	DT
cord-009417-458rrhcm	704	13	epidemic	epidemic	NN
cord-009417-458rrhcm	704	14	of	of	IN
cord-009417-458rrhcm	704	15	transfusionassociated	transfusionassociate	VBN
cord-009417-458rrhcm	704	16	AIDS	AIDS	NNP
cord-009417-458rrhcm	704	17	.	.	.
cord-009417-458rrhcm	705	1	155	155	CD
cord-009417-458rrhcm	705	2	Most	Most	JJS
cord-009417-458rrhcm	705	3	states	state	NNS
cord-009417-458rrhcm	705	4	regulate	regulate	VBP
cord-009417-458rrhcm	705	5	blood	blood	NN
cord-009417-458rrhcm	705	6	banking	banking	NN
cord-009417-458rrhcm	705	7	and	and	CC
cord-009417-458rrhcm	705	8	medical	medical	JJ
cord-009417-458rrhcm	705	9	practice	practice	NN
cord-009417-458rrhcm	705	10	,	,	,
cord-009417-458rrhcm	705	11	but	but	CC
cord-009417-458rrhcm	705	12	blood	blood	NN
cord-009417-458rrhcm	705	13	products	product	NNS
cord-009417-458rrhcm	705	14	are	be	VBP
cord-009417-458rrhcm	705	15	regarded	regard	VBN
cord-009417-458rrhcm	705	16	as	as	IN
cord-009417-458rrhcm	705	17	Symptomatic	symptomatic	JJ
cord-009417-458rrhcm	705	18	hyperviscosity	hyperviscosity	NN
cord-009417-458rrhcm	705	19	Thrombotic	Thrombotic	NNP
cord-009417-458rrhcm	705	20	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	705	21	purpura	purpura	NN
cord-009417-458rrhcm	705	22	Neurologic	neurologic	JJ
cord-009417-458rrhcm	705	23	diseases	disease	NNS
cord-009417-458rrhcm	705	24	:	:	:
cord-009417-458rrhcm	705	25	myasthenia	myasthenia	NN
cord-009417-458rrhcm	705	26	gravis	gravis	NN
cord-009417-458rrhcm	705	27	,	,	.
cord-009417-458rrhcm	706	1	Guillain	Guillain	NNP
cord-009417-458rrhcm	706	2	-	-	HYPH
cord-009417-458rrhcm	706	3	Barré	Barré	NNP
cord-009417-458rrhcm	706	4	syndrome	syndrome	NN
cord-009417-458rrhcm	706	5	Uncontrolled	uncontrolled	JJ
cord-009417-458rrhcm	706	6	systemic	systemic	JJ
cord-009417-458rrhcm	706	7	vasculitis	vasculitis	NN
cord-009417-458rrhcm	706	8	with	with	IN
cord-009417-458rrhcm	706	9	critical	critical	JJ
cord-009417-458rrhcm	706	10	end	end	NN
cord-009417-458rrhcm	706	11	-	-	HYPH
cord-009417-458rrhcm	706	12	organ	organ	NN
cord-009417-458rrhcm	706	13	injury	injury	NN
cord-009417-458rrhcm	707	1	Symptomatic	symptomatic	JJ
cord-009417-458rrhcm	707	2	leukocytosis	leukocytosis	NN
cord-009417-458rrhcm	707	3	Symptomatic	symptomatic	JJ
cord-009417-458rrhcm	707	4	thrombocythemia	thrombocythemia	NNP
cord-009417-458rrhcm	707	5	Sickle	Sickle	NNP
cord-009417-458rrhcm	707	6	cell	cell	NN
cord-009417-458rrhcm	707	7	anemia	anemia	NN
cord-009417-458rrhcm	707	8	crisis	crisis	NN
cord-009417-458rrhcm	707	9	(	(	-LRB-
cord-009417-458rrhcm	707	10	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	707	11	or	or	CC
cord-009417-458rrhcm	707	12	central	central	JJ
cord-009417-458rrhcm	707	13	nervous	nervous	JJ
cord-009417-458rrhcm	707	14	system	system	NN
cord-009417-458rrhcm	707	15	manifestations	manifestation	NNS
cord-009417-458rrhcm	707	16	)	)	-RRB-
cord-009417-458rrhcm	707	17	a	a	DT
cord-009417-458rrhcm	707	18	service	service	NN
cord-009417-458rrhcm	707	19	,	,	,
cord-009417-458rrhcm	707	20	not	not	RB
cord-009417-458rrhcm	707	21	as	as	IN
cord-009417-458rrhcm	707	22	a	a	DT
cord-009417-458rrhcm	707	23	commodity	commodity	NN
cord-009417-458rrhcm	707	24	,	,	,
cord-009417-458rrhcm	708	1	so	so	RB
cord-009417-458rrhcm	708	2	standard	standard	JJ
cord-009417-458rrhcm	708	3	product	product	NN
cord-009417-458rrhcm	708	4	liability	liability	NN
cord-009417-458rrhcm	708	5	does	do	VBZ
cord-009417-458rrhcm	708	6	not	not	RB
cord-009417-458rrhcm	708	7	pertain	pertain	VB
cord-009417-458rrhcm	708	8	to	to	IN
cord-009417-458rrhcm	708	9	blood	blood	NN
cord-009417-458rrhcm	708	10	components	component	NNS
cord-009417-458rrhcm	708	11	.	.	.
cord-009417-458rrhcm	709	1	156	156	CD
cord-009417-458rrhcm	710	1	However	however	RB
cord-009417-458rrhcm	710	2	,	,	,
cord-009417-458rrhcm	710	3	negligence	negligence	NN
cord-009417-458rrhcm	710	4	in	in	IN
cord-009417-458rrhcm	710	5	the	the	DT
cord-009417-458rrhcm	710	6	course	course	NN
cord-009417-458rrhcm	710	7	of	of	IN
cord-009417-458rrhcm	710	8	preparing	prepare	VBG
cord-009417-458rrhcm	710	9	,	,	,
cord-009417-458rrhcm	710	10	testing	test	VBG
cord-009417-458rrhcm	710	11	,	,	,
cord-009417-458rrhcm	710	12	transferring	transfer	VBG
cord-009417-458rrhcm	710	13	,	,	,
cord-009417-458rrhcm	710	14	crossmatching	crossmatching	NN
cord-009417-458rrhcm	710	15	,	,	,
cord-009417-458rrhcm	710	16	or	or	CC
cord-009417-458rrhcm	710	17	administering	administer	VBG
cord-009417-458rrhcm	710	18	blood	blood	NN
cord-009417-458rrhcm	710	19	products	product	NNS
cord-009417-458rrhcm	710	20	is	be	VBZ
cord-009417-458rrhcm	710	21	still	still	RB
cord-009417-458rrhcm	710	22	a	a	DT
cord-009417-458rrhcm	710	23	potential	potential	JJ
cord-009417-458rrhcm	710	24	cause	cause	NN
cord-009417-458rrhcm	710	25	for	for	IN
cord-009417-458rrhcm	710	26	legal	legal	JJ
cord-009417-458rrhcm	710	27	action	action	NN
cord-009417-458rrhcm	710	28	.	.	.
cord-009417-458rrhcm	711	1	Every	every	DT
cord-009417-458rrhcm	711	2	clinician	clinician	NN
cord-009417-458rrhcm	711	3	who	who	WP
cord-009417-458rrhcm	711	4	orders	order	VBZ
cord-009417-458rrhcm	711	5	transfusions	transfusion	NNS
cord-009417-458rrhcm	711	6	must	must	MD
cord-009417-458rrhcm	711	7	be	be	VB
cord-009417-458rrhcm	711	8	aware	aware	JJ
cord-009417-458rrhcm	711	9	that	that	IN
cord-009417-458rrhcm	711	10	blood	blood	NN
cord-009417-458rrhcm	711	11	components	component	NNS
cord-009417-458rrhcm	711	12	,	,	,
cord-009417-458rrhcm	711	13	like	like	IN
cord-009417-458rrhcm	711	14	drugs	drug	NNS
cord-009417-458rrhcm	711	15	,	,	,
cord-009417-458rrhcm	711	16	are	be	VBP
cord-009417-458rrhcm	711	17	approved	approve	VBN
cord-009417-458rrhcm	711	18	for	for	IN
cord-009417-458rrhcm	711	19	specifi	specifi	NNP
cord-009417-458rrhcm	711	20	c	c	NN
cord-009417-458rrhcm	711	21	uses	use	VBZ
cord-009417-458rrhcm	711	22	and	and	CC
cord-009417-458rrhcm	711	23	that	that	IN
cord-009417-458rrhcm	711	24	the	the	DT
cord-009417-458rrhcm	711	25	indications	indication	NNS
cord-009417-458rrhcm	711	26	should	should	MD
cord-009417-458rrhcm	711	27	be	be	VB
cord-009417-458rrhcm	711	28	clearly	clearly	RB
cord-009417-458rrhcm	711	29	documented	document	VBN
cord-009417-458rrhcm	711	30	in	in	IN
cord-009417-458rrhcm	711	31	the	the	DT
cord-009417-458rrhcm	711	32	medical	medical	JJ
cord-009417-458rrhcm	711	33	record	record	NN
cord-009417-458rrhcm	711	34	.	.	.
cord-009417-458rrhcm	712	1	The	the	DT
cord-009417-458rrhcm	712	2	informed	informed	JJ
cord-009417-458rrhcm	712	3	consent	consent	NN
cord-009417-458rrhcm	712	4	of	of	IN
cord-009417-458rrhcm	712	5	the	the	DT
cord-009417-458rrhcm	712	6	patient	patient	NN
cord-009417-458rrhcm	712	7	is	be	VBZ
cord-009417-458rrhcm	712	8	an	an	DT
cord-009417-458rrhcm	712	9	important	important	JJ
cord-009417-458rrhcm	712	10	area	area	NN
cord-009417-458rrhcm	712	11	of	of	IN
cord-009417-458rrhcm	712	12	potential	potential	JJ
cord-009417-458rrhcm	712	13	liability	liability	NN
cord-009417-458rrhcm	712	14	.	.	.
cord-009417-458rrhcm	713	1	The	the	DT
cord-009417-458rrhcm	713	2	Joint	Joint	NNP
cord-009417-458rrhcm	713	3	Commission	Commission	NNP
cord-009417-458rrhcm	713	4	on	on	IN
cord-009417-458rrhcm	713	5	Accreditation	Accreditation	NNP
cord-009417-458rrhcm	713	6	of	of	IN
cord-009417-458rrhcm	713	7	Healthcare	Healthcare	NNP
cord-009417-458rrhcm	713	8	Organizations	Organizations	NNP
cord-009417-458rrhcm	713	9	(	(	-LRB-
cord-009417-458rrhcm	713	10	JCAHO	JCAHO	NNP
cord-009417-458rrhcm	713	11	)	)	-RRB-
cord-009417-458rrhcm	713	12	has	have	VBZ
cord-009417-458rrhcm	713	13	required	require	VBN
cord-009417-458rrhcm	713	14	written	write	VBN
cord-009417-458rrhcm	713	15	patient	patient	JJ
cord-009417-458rrhcm	713	16	consent	consent	NN
cord-009417-458rrhcm	713	17	for	for	IN
cord-009417-458rrhcm	713	18	blood	blood	NN
cord-009417-458rrhcm	713	19	transfusions	transfusion	NNS
cord-009417-458rrhcm	713	20	since	since	IN
cord-009417-458rrhcm	713	21	1996	1996	CD
cord-009417-458rrhcm	713	22	.	.	.
cord-009417-458rrhcm	714	1	What	what	WP
cord-009417-458rrhcm	714	2	constitutes	constitute	VBZ
cord-009417-458rrhcm	714	3	adequate	adequate	JJ
cord-009417-458rrhcm	714	4	informed	informed	JJ
cord-009417-458rrhcm	714	5	consent	consent	NN
cord-009417-458rrhcm	714	6	and	and	CC
cord-009417-458rrhcm	714	7	who	who	WP
cord-009417-458rrhcm	714	8	is	be	VBZ
cord-009417-458rrhcm	714	9	responsible	responsible	JJ
cord-009417-458rrhcm	714	10	for	for	IN
cord-009417-458rrhcm	714	11	advising	advise	VBG
cord-009417-458rrhcm	714	12	the	the	DT
cord-009417-458rrhcm	714	13	patient	patient	NN
cord-009417-458rrhcm	714	14	are	be	VBP
cord-009417-458rrhcm	714	15	still	still	RB
cord-009417-458rrhcm	714	16	in	in	IN
cord-009417-458rrhcm	714	17	contention	contention	NN
cord-009417-458rrhcm	714	18	.	.	.
cord-009417-458rrhcm	715	1	Elements	element	NNS
cord-009417-458rrhcm	715	2	of	of	IN
cord-009417-458rrhcm	715	3	informed	informed	JJ
cord-009417-458rrhcm	715	4	consent	consent	NN
cord-009417-458rrhcm	715	5	include	include	VBP
cord-009417-458rrhcm	715	6	an	an	DT
cord-009417-458rrhcm	715	7	understanding	understanding	NN
cord-009417-458rrhcm	715	8	of	of	IN
cord-009417-458rrhcm	715	9	the	the	DT
cord-009417-458rrhcm	715	10	need	need	NN
cord-009417-458rrhcm	715	11	for	for	IN
cord-009417-458rrhcm	715	12	transfusion	transfusion	NN
cord-009417-458rrhcm	715	13	,	,	,
cord-009417-458rrhcm	715	14	its	-PRON-	PRP$
cord-009417-458rrhcm	715	15	risks	risk	NNS
cord-009417-458rrhcm	715	16	and	and	CC
cord-009417-458rrhcm	715	17	benefi	benefi	NNP
cord-009417-458rrhcm	715	18	ts	ts	NNP
cord-009417-458rrhcm	715	19	,	,	,
cord-009417-458rrhcm	715	20	and	and	CC
cord-009417-458rrhcm	715	21	the	the	DT
cord-009417-458rrhcm	715	22	alternatives	alternative	NNS
cord-009417-458rrhcm	715	23	,	,	,
cord-009417-458rrhcm	715	24	including	include	VBG
cord-009417-458rrhcm	715	25	the	the	DT
cord-009417-458rrhcm	715	26	risk	risk	NN
cord-009417-458rrhcm	715	27	of	of	IN
cord-009417-458rrhcm	715	28	not	not	RB
cord-009417-458rrhcm	715	29	undergoing	undergo	VBG
cord-009417-458rrhcm	715	30	transfusion	transfusion	NN
cord-009417-458rrhcm	715	31	,	,	,
cord-009417-458rrhcm	715	32	as	as	RB
cord-009417-458rrhcm	715	33	well	well	RB
cord-009417-458rrhcm	715	34	as	as	IN
cord-009417-458rrhcm	715	35	the	the	DT
cord-009417-458rrhcm	715	36	opportunity	opportunity	NN
cord-009417-458rrhcm	715	37	to	to	TO
cord-009417-458rrhcm	715	38	ask	ask	VB
cord-009417-458rrhcm	715	39	questions	question	NNS
cord-009417-458rrhcm	715	40	.	.	.
cord-009417-458rrhcm	716	1	Whether	whether	IN
cord-009417-458rrhcm	716	2	the	the	DT
cord-009417-458rrhcm	716	3	clinician	clinician	NN
cord-009417-458rrhcm	716	4	documents	document	NNS
cord-009417-458rrhcm	716	5	informed	informed	JJ
cord-009417-458rrhcm	716	6	consent	consent	NN
cord-009417-458rrhcm	716	7	with	with	IN
cord-009417-458rrhcm	716	8	an	an	DT
cord-009417-458rrhcm	716	9	individual	individual	JJ
cord-009417-458rrhcm	716	10	progress	progress	NN
cord-009417-458rrhcm	716	11	note	note	NN
cord-009417-458rrhcm	716	12	in	in	IN
cord-009417-458rrhcm	716	13	the	the	DT
cord-009417-458rrhcm	716	14	patient	patient	JJ
cord-009417-458rrhcm	716	15	record	record	NN
cord-009417-458rrhcm	716	16	or	or	CC
cord-009417-458rrhcm	716	17	with	with	IN
cord-009417-458rrhcm	716	18	a	a	DT
cord-009417-458rrhcm	716	19	standardized	standardized	JJ
cord-009417-458rrhcm	716	20	form	form	NN
cord-009417-458rrhcm	716	21	is	be	VBZ
cord-009417-458rrhcm	716	22	generally	generally	RB
cord-009417-458rrhcm	716	23	established	establish	VBN
cord-009417-458rrhcm	716	24	as	as	IN
cord-009417-458rrhcm	716	25	institutional	institutional	JJ
cord-009417-458rrhcm	716	26	policy	policy	NN
cord-009417-458rrhcm	716	27	.	.	.
cord-009417-458rrhcm	717	1	Similarly	similarly	RB
cord-009417-458rrhcm	717	2	,	,	,
cord-009417-458rrhcm	717	3	institutions	institution	NNS
cord-009417-458rrhcm	717	4	vary	vary	VBP
cord-009417-458rrhcm	717	5	with	with	IN
cord-009417-458rrhcm	717	6	respect	respect	NN
cord-009417-458rrhcm	717	7	to	to	IN
cord-009417-458rrhcm	717	8	policies	policy	NNS
cord-009417-458rrhcm	717	9	for	for	IN
cord-009417-458rrhcm	717	10	consenting	consent	VBG
cord-009417-458rrhcm	717	11	adults	adult	NNS
cord-009417-458rrhcm	717	12	who	who	WP
cord-009417-458rrhcm	717	13	are	be	VBP
cord-009417-458rrhcm	717	14	temporarily	temporarily	RB
cord-009417-458rrhcm	717	15	incompetent	incompetent	JJ
cord-009417-458rrhcm	717	16	,	,	,
cord-009417-458rrhcm	717	17	such	such	JJ
cord-009417-458rrhcm	717	18	as	as	IN
cord-009417-458rrhcm	717	19	sedated	sedated	JJ
cord-009417-458rrhcm	717	20	patients	patient	NNS
cord-009417-458rrhcm	717	21	in	in	IN
cord-009417-458rrhcm	717	22	the	the	DT
cord-009417-458rrhcm	717	23	ICU	ICU	NNP
cord-009417-458rrhcm	717	24	.	.	.
cord-009417-458rrhcm	718	1	A	a	DT
cord-009417-458rrhcm	718	2	competent	competent	JJ
cord-009417-458rrhcm	718	3	adult	adult	NN
cord-009417-458rrhcm	718	4	patient	patient	NN
cord-009417-458rrhcm	718	5	may	may	MD
cord-009417-458rrhcm	718	6	refuse	refuse	VB
cord-009417-458rrhcm	718	7	blood	blood	NN
cord-009417-458rrhcm	718	8	transfusion	transfusion	NN
cord-009417-458rrhcm	718	9	,	,	,
cord-009417-458rrhcm	718	10	and	and	CC
cord-009417-458rrhcm	718	11	Jehovah	Jehovah	NNP
cord-009417-458rrhcm	718	12	's	's	POS
cord-009417-458rrhcm	718	13	Witnesses	witness	NNS
cord-009417-458rrhcm	718	14	commonly	commonly	RB
cord-009417-458rrhcm	718	15	do	do	VBP
cord-009417-458rrhcm	718	16	so	so	RB
cord-009417-458rrhcm	718	17	for	for	IN
cord-009417-458rrhcm	718	18	religious	religious	JJ
cord-009417-458rrhcm	718	19	reasons	reason	NNS
cord-009417-458rrhcm	718	20	.	.	.
cord-009417-458rrhcm	719	1	Case	case	NN
cord-009417-458rrhcm	719	2	law	law	NN
cord-009417-458rrhcm	719	3	is	be	VBZ
cord-009417-458rrhcm	719	4	clear	clear	JJ
cord-009417-458rrhcm	719	5	in	in	IN
cord-009417-458rrhcm	719	6	upholding	uphold	VBG
cord-009417-458rrhcm	719	7	this	this	DT
cord-009417-458rrhcm	719	8	right	right	NN
cord-009417-458rrhcm	719	9	of	of	IN
cord-009417-458rrhcm	719	10	the	the	DT
cord-009417-458rrhcm	719	11	patient	patient	NN
cord-009417-458rrhcm	719	12	,	,	,
cord-009417-458rrhcm	719	13	157	157	CD
cord-009417-458rrhcm	719	14	which	which	WDT
cord-009417-458rrhcm	719	15	extends	extend	VBZ
cord-009417-458rrhcm	719	16	to	to	TO
cord-009417-458rrhcm	719	17	care	care	VB
cord-009417-458rrhcm	719	18	given	give	VBN
cord-009417-458rrhcm	719	19	at	at	IN
cord-009417-458rrhcm	719	20	such	such	JJ
cord-009417-458rrhcm	719	21	time	time	NN
cord-009417-458rrhcm	719	22	as	as	IN
cord-009417-458rrhcm	719	23	the	the	DT
cord-009417-458rrhcm	719	24	patient	patient	NN
cord-009417-458rrhcm	719	25	may	may	MD
cord-009417-458rrhcm	719	26	become	become	VB
cord-009417-458rrhcm	719	27	incompetent	incompetent	JJ
cord-009417-458rrhcm	719	28	(	(	-LRB-
cord-009417-458rrhcm	719	29	i.e.	i.e.	FW
cord-009417-458rrhcm	719	30	,	,	,
cord-009417-458rrhcm	719	31	comatose	comatose	JJ
cord-009417-458rrhcm	719	32	)	)	-RRB-
cord-009417-458rrhcm	719	33	after	after	IN
cord-009417-458rrhcm	719	34	such	such	JJ
cord-009417-458rrhcm	719	35	refusal	refusal	NN
cord-009417-458rrhcm	719	36	was	be	VBD
cord-009417-458rrhcm	719	37	expressed	express	VBN
cord-009417-458rrhcm	719	38	before	before	IN
cord-009417-458rrhcm	719	39	becoming	become	VBG
cord-009417-458rrhcm	719	40	incompetent	incompetent	JJ
cord-009417-458rrhcm	719	41	.	.	.
cord-009417-458rrhcm	720	1	Courts	court	NNS
cord-009417-458rrhcm	720	2	will	will	MD
cord-009417-458rrhcm	720	3	usually	usually	RB
cord-009417-458rrhcm	720	4	order	order	VB
cord-009417-458rrhcm	720	5	a	a	DT
cord-009417-458rrhcm	720	6	lifesaving	lifesaving	JJ
cord-009417-458rrhcm	720	7	transfusion	transfusion	NN
cord-009417-458rrhcm	720	8	for	for	IN
cord-009417-458rrhcm	720	9	minors	minor	NNS
cord-009417-458rrhcm	720	10	.	.	.
cord-009417-458rrhcm	721	1	Exceptions	exception	NNS
cord-009417-458rrhcm	721	2	have	have	VBP
cord-009417-458rrhcm	721	3	been	be	VBN
cord-009417-458rrhcm	721	4	made	make	VBN
cord-009417-458rrhcm	721	5	in	in	IN
cord-009417-458rrhcm	721	6	the	the	DT
cord-009417-458rrhcm	721	7	case	case	NN
cord-009417-458rrhcm	721	8	of	of	IN
cord-009417-458rrhcm	721	9	some	some	DT
cord-009417-458rrhcm	721	10	"	"	``
cord-009417-458rrhcm	721	11	emancipated	emancipated	JJ
cord-009417-458rrhcm	721	12	minors	minor	NNS
cord-009417-458rrhcm	721	13	"	"	''
cord-009417-458rrhcm	721	14	who	who	WP
cord-009417-458rrhcm	721	15	are	be	VBP
cord-009417-458rrhcm	721	16	at	at	IN
cord-009417-458rrhcm	721	17	the	the	DT
cord-009417-458rrhcm	721	18	age	age	NN
cord-009417-458rrhcm	721	19	of	of	IN
cord-009417-458rrhcm	721	20	reason	reason	NN
cord-009417-458rrhcm	721	21	.	.	.
cord-009417-458rrhcm	722	1	Most	Most	JJS
cord-009417-458rrhcm	722	2	states	state	NNS
cord-009417-458rrhcm	722	3	have	have	VBP
cord-009417-458rrhcm	722	4	evoked	evoke	VBN
cord-009417-458rrhcm	722	5	a	a	DT
cord-009417-458rrhcm	722	6	"	"	``
cord-009417-458rrhcm	722	7	special	special	JJ
cord-009417-458rrhcm	722	8	interest	interest	NN
cord-009417-458rrhcm	722	9	"	"	''
cord-009417-458rrhcm	722	10	in	in	IN
cord-009417-458rrhcm	722	11	the	the	DT
cord-009417-458rrhcm	722	12	welfare	welfare	NN
cord-009417-458rrhcm	722	13	of	of	IN
cord-009417-458rrhcm	722	14	a	a	DT
cord-009417-458rrhcm	722	15	fetus	fetus	NN
cord-009417-458rrhcm	722	16	in	in	IN
cord-009417-458rrhcm	722	17	ordering	order	VBG
cord-009417-458rrhcm	722	18	transfusions	transfusion	NNS
cord-009417-458rrhcm	722	19	to	to	IN
cord-009417-458rrhcm	722	20	pregnant	pregnant	JJ
cord-009417-458rrhcm	722	21	women	woman	NNS
cord-009417-458rrhcm	722	22	.	.	.
cord-009417-458rrhcm	723	1	The	the	DT
cord-009417-458rrhcm	723	2	advent	advent	NN
cord-009417-458rrhcm	723	3	of	of	IN
cord-009417-458rrhcm	723	4	sentinel	sentinel	JJ
cord-009417-458rrhcm	723	5	event	event	NN
cord-009417-458rrhcm	723	6	reviews	review	NNS
cord-009417-458rrhcm	723	7	and	and	CC
cord-009417-458rrhcm	723	8	other	other	JJ
cord-009417-458rrhcm	723	9	quality	quality	NN
cord-009417-458rrhcm	723	10	management	management	NN
cord-009417-458rrhcm	723	11	procedures	procedure	NNS
cord-009417-458rrhcm	723	12	for	for	IN
cord-009417-458rrhcm	723	13	patient	patient	JJ
cord-009417-458rrhcm	723	14	safety	safety	NN
cord-009417-458rrhcm	723	15	has	have	VBZ
cord-009417-458rrhcm	723	16	had	have	VBN
cord-009417-458rrhcm	723	17	an	an	DT
cord-009417-458rrhcm	723	18	impact	impact	NN
cord-009417-458rrhcm	723	19	on	on	IN
cord-009417-458rrhcm	723	20	transfusion	transfusion	NN
cord-009417-458rrhcm	723	21	practice	practice	NN
cord-009417-458rrhcm	723	22	as	as	RB
cord-009417-458rrhcm	723	23	well	well	RB
cord-009417-458rrhcm	723	24	.	.	.
cord-009417-458rrhcm	724	1	Procedures	procedure	NNS
cord-009417-458rrhcm	724	2	for	for	IN
cord-009417-458rrhcm	724	3	patient	patient	JJ
cord-009417-458rrhcm	724	4	identifi	identifi	NNP
cord-009417-458rrhcm	724	5	cation	cation	NN
cord-009417-458rrhcm	724	6	before	before	IN
cord-009417-458rrhcm	724	7	surgical	surgical	JJ
cord-009417-458rrhcm	724	8	procedures	procedure	NNS
cord-009417-458rrhcm	724	9	,	,	,
cord-009417-458rrhcm	724	10	including	include	VBG
cord-009417-458rrhcm	724	11	devices	device	NNS
cord-009417-458rrhcm	724	12	such	such	JJ
cord-009417-458rrhcm	724	13	as	as	IN
cord-009417-458rrhcm	724	14	bar	bar	NN
cord-009417-458rrhcm	724	15	code	code	NN
cord-009417-458rrhcm	724	16	readers	reader	NNS
cord-009417-458rrhcm	724	17	,	,	,
cord-009417-458rrhcm	724	18	have	have	VBP
cord-009417-458rrhcm	724	19	also	also	RB
cord-009417-458rrhcm	724	20	been	be	VBN
cord-009417-458rrhcm	724	21	applied	apply	VBN
cord-009417-458rrhcm	724	22	to	to	IN
cord-009417-458rrhcm	724	23	transfusion	transfusion	NN
cord-009417-458rrhcm	724	24	practice	practice	NN
cord-009417-458rrhcm	724	25	.	.	.
cord-009417-458rrhcm	725	1	However	however	RB
cord-009417-458rrhcm	725	2	,	,	,
cord-009417-458rrhcm	725	3	annual	annual	JJ
cord-009417-458rrhcm	725	4	sentinel	sentinel	JJ
cord-009417-458rrhcm	725	5	event	event	NN
cord-009417-458rrhcm	725	6	reviews	review	NNS
cord-009417-458rrhcm	725	7	reporting	report	VBG
cord-009417-458rrhcm	725	8	transfusion	transfusion	NN
cord-009417-458rrhcm	725	9	errors	error	NNS
cord-009417-458rrhcm	725	10	have	have	VBP
cord-009417-458rrhcm	725	11	remained	remain	VBN
cord-009417-458rrhcm	725	12	constant	constant	JJ
cord-009417-458rrhcm	725	13	according	accord	VBG
cord-009417-458rrhcm	725	14	to	to	IN
cord-009417-458rrhcm	725	15	JCAHO	JCAHO	NNP
cord-009417-458rrhcm	725	16	records	record	NNS
cord-009417-458rrhcm	725	17	.	.	.
cord-009417-458rrhcm	726	1	158	158	CD
cord-009417-458rrhcm	726	2	 	 	_SP
cord-009417-458rrhcm	726	3	■	■	NNP
cord-009417-458rrhcm	726	4	Blood	blood	NN
cord-009417-458rrhcm	726	5	components	component	NNS
cord-009417-458rrhcm	726	6	should	should	MD
cord-009417-458rrhcm	726	7	be	be	VB
cord-009417-458rrhcm	726	8	prescribed	prescribe	VBN
cord-009417-458rrhcm	726	9	like	like	IN
cord-009417-458rrhcm	726	10	drugs	drug	NNS
cord-009417-458rrhcm	726	11	.	.	.
cord-009417-458rrhcm	727	1	Appropriate	appropriate	JJ
cord-009417-458rrhcm	727	2	blood	blood	NN
cord-009417-458rrhcm	727	3	component	component	NN
cord-009417-458rrhcm	727	4	therapy	therapy	NN
cord-009417-458rrhcm	727	5	requires	require	VBZ
cord-009417-458rrhcm	727	6	that	that	IN
cord-009417-458rrhcm	727	7	the	the	DT
cord-009417-458rrhcm	727	8	specifi	specifi	NN
cord-009417-458rrhcm	727	9	c	c	SYM
cord-009417-458rrhcm	727	10	blood	blood	NN
cord-009417-458rrhcm	727	11	product	product	NN
cord-009417-458rrhcm	727	12	needed	need	VBN
cord-009417-458rrhcm	727	13	for	for	IN
cord-009417-458rrhcm	727	14	a	a	DT
cord-009417-458rrhcm	727	15	clear	clear	JJ
cord-009417-458rrhcm	727	16	indication	indication	NN
cord-009417-458rrhcm	727	17	be	be	VB
cord-009417-458rrhcm	727	18	prescribed	prescribe	VBN
cord-009417-458rrhcm	727	19	,	,	,
cord-009417-458rrhcm	727	20	with	with	IN
cord-009417-458rrhcm	727	21	avoidance	avoidance	NN
cord-009417-458rrhcm	727	22	of	of	IN
cord-009417-458rrhcm	727	23	a	a	DT
cord-009417-458rrhcm	727	24	formulaic	formulaic	JJ
cord-009417-458rrhcm	727	25	approach	approach	NN
cord-009417-458rrhcm	727	26	.	.	.
cord-009417-458rrhcm	728	1	■	■	NFP
cord-009417-458rrhcm	728	2	Red	red	JJ
cord-009417-458rrhcm	728	3	blood	blood	NN
cord-009417-458rrhcm	728	4	cells	cell	NNS
cord-009417-458rrhcm	728	5	should	should	MD
cord-009417-458rrhcm	728	6	be	be	VB
cord-009417-458rrhcm	728	7	transfused	transfuse	VBN
cord-009417-458rrhcm	728	8	only	only	RB
cord-009417-458rrhcm	728	9	to	to	TO
cord-009417-458rrhcm	728	10	increase	increase	VB
cord-009417-458rrhcm	728	11	oxygen	oxygen	NN
cord-009417-458rrhcm	728	12	-	-	HYPH
cord-009417-458rrhcm	728	13	carrying	carry	VBG
cord-009417-458rrhcm	728	14	capacity	capacity	NN
cord-009417-458rrhcm	728	15	.	.	.
cord-009417-458rrhcm	729	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	729	2	decisions	decision	NNS
cord-009417-458rrhcm	729	3	should	should	MD
cord-009417-458rrhcm	729	4	be	be	VB
cord-009417-458rrhcm	729	5	based	base	VBN
cord-009417-458rrhcm	729	6	on	on	IN
cord-009417-458rrhcm	729	7	individual	individual	JJ
cord-009417-458rrhcm	729	8	patient	patient	NN
cord-009417-458rrhcm	729	9	physiology	physiology	NN
cord-009417-458rrhcm	729	10	.	.	.
cord-009417-458rrhcm	730	1	The	the	DT
cord-009417-458rrhcm	730	2	majority	majority	NN
cord-009417-458rrhcm	730	3	of	of	IN
cord-009417-458rrhcm	730	4	patients	patient	NNS
cord-009417-458rrhcm	730	5	with	with	IN
cord-009417-458rrhcm	730	6	hemoglobin	hemoglobin	NN
cord-009417-458rrhcm	730	7	levels	level	NNS
cord-009417-458rrhcm	730	8	greater	great	JJR
cord-009417-458rrhcm	730	9	than	than	IN
cord-009417-458rrhcm	730	10	60	60	CD
cord-009417-458rrhcm	730	11	or	or	CC
cord-009417-458rrhcm	730	12	70	70	CD
cord-009417-458rrhcm	730	13	g	g	NN
cord-009417-458rrhcm	730	14	/	/	SYM
cord-009417-458rrhcm	730	15	L	L	NNP
cord-009417-458rrhcm	730	16	will	will	MD
cord-009417-458rrhcm	730	17	not	not	RB
cord-009417-458rrhcm	730	18	require	require	VB
cord-009417-458rrhcm	730	19	transfusion	transfusion	NN
cord-009417-458rrhcm	730	20	unless	unless	IN
cord-009417-458rrhcm	730	21	they	-PRON-	PRP
cord-009417-458rrhcm	730	22	have	have	VBP
cord-009417-458rrhcm	730	23	limited	limit	VBN
cord-009417-458rrhcm	730	24	cardiopulmonary	cardiopulmonary	JJ
cord-009417-458rrhcm	730	25	reserve	reserve	NN
cord-009417-458rrhcm	730	26	or	or	CC
cord-009417-458rrhcm	730	27	active	active	JJ
cord-009417-458rrhcm	730	28	bleeding	bleeding	NN
cord-009417-458rrhcm	730	29	.	.	.
cord-009417-458rrhcm	731	1	■	■	NFP
cord-009417-458rrhcm	731	2	Platelet	platelet	NN
cord-009417-458rrhcm	731	3	transfusions	transfusion	NNS
cord-009417-458rrhcm	731	4	are	be	VBP
cord-009417-458rrhcm	731	5	indicated	indicate	VBN
cord-009417-458rrhcm	731	6	for	for	IN
cord-009417-458rrhcm	731	7	patients	patient	NNS
cord-009417-458rrhcm	731	8	who	who	WP
cord-009417-458rrhcm	731	9	are	be	VBP
cord-009417-458rrhcm	731	10	bleeding	bleed	VBG
cord-009417-458rrhcm	731	11	because	because	IN
cord-009417-458rrhcm	731	12	of	of	IN
cord-009417-458rrhcm	731	13	thrombocytopenia	thrombocytopenia	NN
cord-009417-458rrhcm	731	14	or	or	CC
cord-009417-458rrhcm	731	15	functional	functional	JJ
cord-009417-458rrhcm	731	16	platelet	platelet	NN
cord-009417-458rrhcm	731	17	defects	defect	NNS
cord-009417-458rrhcm	731	18	.	.	.
cord-009417-458rrhcm	732	1	Guidelines	guideline	NNS
cord-009417-458rrhcm	732	2	for	for	IN
cord-009417-458rrhcm	732	3	platelet	platelet	NN
cord-009417-458rrhcm	732	4	transfusion	transfusion	NN
cord-009417-458rrhcm	732	5	are	be	VBP
cord-009417-458rrhcm	732	6	also	also	RB
cord-009417-458rrhcm	732	7	conservative	conservative	JJ
cord-009417-458rrhcm	732	8	.	.	.
cord-009417-458rrhcm	733	1	Prophylactic	prophylactic	JJ
cord-009417-458rrhcm	733	2	platelet	platelet	NN
cord-009417-458rrhcm	733	3	transfusion	transfusion	NN
cord-009417-458rrhcm	733	4	remains	remain	VBZ
cord-009417-458rrhcm	733	5	controversial	controversial	JJ
cord-009417-458rrhcm	733	6	and	and	CC
cord-009417-458rrhcm	733	7	is	be	VBZ
cord-009417-458rrhcm	733	8	not	not	RB
cord-009417-458rrhcm	733	9	warranted	warrant	VBN
cord-009417-458rrhcm	733	10	in	in	IN
cord-009417-458rrhcm	733	11	many	many	JJ
cord-009417-458rrhcm	733	12	situations	situation	NNS
cord-009417-458rrhcm	733	13	.	.	.
cord-009417-458rrhcm	734	1	■	■	NFP
cord-009417-458rrhcm	734	2	Fresh	fresh	JJ
cord-009417-458rrhcm	734	3	frozen	frozen	JJ
cord-009417-458rrhcm	734	4	plasma	plasma	NN
cord-009417-458rrhcm	734	5	is	be	VBZ
cord-009417-458rrhcm	734	6	indicated	indicate	VBN
cord-009417-458rrhcm	734	7	for	for	IN
cord-009417-458rrhcm	734	8	the	the	DT
cord-009417-458rrhcm	734	9	repletion	repletion	NN
cord-009417-458rrhcm	734	10	of	of	IN
cord-009417-458rrhcm	734	11	coagulation	coagulation	NN
cord-009417-458rrhcm	734	12	factors	factor	NNS
cord-009417-458rrhcm	734	13	in	in	IN
cord-009417-458rrhcm	734	14	bleeding	bleed	VBG
cord-009417-458rrhcm	734	15	patients	patient	NNS
cord-009417-458rrhcm	734	16	defi	defi	NNP
cord-009417-458rrhcm	734	17	cient	cient	NN
cord-009417-458rrhcm	734	18	in	in	IN
cord-009417-458rrhcm	734	19	those	those	DT
cord-009417-458rrhcm	734	20	factors	factor	NNS
cord-009417-458rrhcm	734	21	or	or	CC
cord-009417-458rrhcm	734	22	to	to	TO
cord-009417-458rrhcm	734	23	provide	provide	VB
cord-009417-458rrhcm	734	24	specifi	specifi	NNP
cord-009417-458rrhcm	734	25	c	c	NN
cord-009417-458rrhcm	734	26	plasma	plasma	NN
cord-009417-458rrhcm	734	27	proteins	protein	NNS
cord-009417-458rrhcm	734	28	that	that	WDT
cord-009417-458rrhcm	734	29	can	can	MD
cord-009417-458rrhcm	734	30	not	not	RB
cord-009417-458rrhcm	734	31	be	be	VB
cord-009417-458rrhcm	734	32	obtained	obtain	VBN
cord-009417-458rrhcm	734	33	from	from	IN
cord-009417-458rrhcm	734	34	safer	safe	JJR
cord-009417-458rrhcm	734	35	sources	source	NNS
cord-009417-458rrhcm	734	36	.	.	.
cord-009417-458rrhcm	735	1	■	■	NFP
cord-009417-458rrhcm	735	2	Cryoprecipitate	Cryoprecipitate	NNP
cord-009417-458rrhcm	735	3	is	be	VBZ
cord-009417-458rrhcm	735	4	a	a	DT
cord-009417-458rrhcm	735	5	concentrated	concentrated	JJ
cord-009417-458rrhcm	735	6	source	source	NN
cord-009417-458rrhcm	735	7	of	of	IN
cord-009417-458rrhcm	735	8	fi	fi	NNP
cord-009417-458rrhcm	735	9	brinogen	brinogen	NNP
cord-009417-458rrhcm	735	10	and	and	CC
cord-009417-458rrhcm	735	11	selected	select	VBN
cord-009417-458rrhcm	735	12	coagulation	coagulation	NN
cord-009417-458rrhcm	735	13	factors	factor	NNS
cord-009417-458rrhcm	735	14	.	.	.
cord-009417-458rrhcm	736	1	Cryoprecipitate	Cryoprecipitate	NNP
cord-009417-458rrhcm	736	2	may	may	MD
cord-009417-458rrhcm	736	3	be	be	VB
cord-009417-458rrhcm	736	4	more	more	RBR
cord-009417-458rrhcm	736	5	helpful	helpful	JJ
cord-009417-458rrhcm	736	6	in	in	IN
cord-009417-458rrhcm	736	7	correcting	correct	VBG
cord-009417-458rrhcm	736	8	the	the	DT
cord-009417-458rrhcm	736	9	hypofi	hypofi	NNP
cord-009417-458rrhcm	736	10	brinogenemia	brinogenemia	NN
cord-009417-458rrhcm	736	11	of	of	IN
cord-009417-458rrhcm	736	12	dilutional	dilutional	JJ
cord-009417-458rrhcm	736	13	or	or	CC
cord-009417-458rrhcm	736	14	consumptive	consumptive	JJ
cord-009417-458rrhcm	736	15	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	736	16	than	than	IN
cord-009417-458rrhcm	736	17	fresh	fresh	JJ
cord-009417-458rrhcm	736	18	frozen	frozen	JJ
cord-009417-458rrhcm	736	19	plasma	plasma	NN
cord-009417-458rrhcm	736	20	.	.	.
cord-009417-458rrhcm	737	1	■	■	NFP
cord-009417-458rrhcm	737	2	Adverse	adverse	JJ
cord-009417-458rrhcm	737	3	reactions	reaction	NNS
cord-009417-458rrhcm	737	4	to	to	IN
cord-009417-458rrhcm	737	5	blood	blood	NN
cord-009417-458rrhcm	737	6	components	component	NNS
cord-009417-458rrhcm	737	7	occur	occur	VBP
cord-009417-458rrhcm	737	8	in	in	IN
cord-009417-458rrhcm	737	9	1	1	CD
cord-009417-458rrhcm	737	10	%	%	NN
cord-009417-458rrhcm	737	11	to	to	TO
cord-009417-458rrhcm	737	12	2	2	CD
cord-009417-458rrhcm	737	13	%	%	NN
cord-009417-458rrhcm	737	14	of	of	IN
cord-009417-458rrhcm	737	15	transfusion	transfusion	NN
cord-009417-458rrhcm	737	16	episodes	episode	NNS
cord-009417-458rrhcm	737	17	.	.	.
cord-009417-458rrhcm	738	1	Adherence	adherence	NN
cord-009417-458rrhcm	738	2	to	to	IN
cord-009417-458rrhcm	738	3	routine	routine	JJ
cord-009417-458rrhcm	738	4	protocols	protocol	NNS
cord-009417-458rrhcm	738	5	for	for	IN
cord-009417-458rrhcm	738	6	the	the	DT
cord-009417-458rrhcm	738	7	evaluation	evaluation	NN
cord-009417-458rrhcm	738	8	of	of	IN
cord-009417-458rrhcm	738	9	transfusion	transfusion	NN
cord-009417-458rrhcm	738	10	reactions	reaction	NNS
cord-009417-458rrhcm	738	11	may	may	MD
cord-009417-458rrhcm	738	12	save	save	VB
cord-009417-458rrhcm	738	13	lives	life	NNS
cord-009417-458rrhcm	738	14	.	.	.
cord-009417-458rrhcm	739	1	■	■	NFP
cord-009417-458rrhcm	739	2	Acute	acute	JJ
cord-009417-458rrhcm	739	3	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	739	4	reactions	reaction	NNS
cord-009417-458rrhcm	739	5	are	be	VBP
cord-009417-458rrhcm	739	6	the	the	DT
cord-009417-458rrhcm	739	7	leading	leading	JJ
cord-009417-458rrhcm	739	8	cause	cause	NN
cord-009417-458rrhcm	739	9	of	of	IN
cord-009417-458rrhcm	739	10	immediate	immediate	JJ
cord-009417-458rrhcm	739	11	transfusion	transfusion	NN
cord-009417-458rrhcm	739	12	fatalities	fatality	NNS
cord-009417-458rrhcm	739	13	.	.	.
cord-009417-458rrhcm	740	1	Prevention	prevention	NN
cord-009417-458rrhcm	740	2	of	of	IN
cord-009417-458rrhcm	740	3	these	these	DT
cord-009417-458rrhcm	740	4	reactions	reaction	NNS
cord-009417-458rrhcm	740	5	requires	require	VBZ
cord-009417-458rrhcm	740	6	strict	strict	JJ
cord-009417-458rrhcm	740	7	adherence	adherence	NN
cord-009417-458rrhcm	740	8	to	to	IN
cord-009417-458rrhcm	740	9	transfusion	transfusion	NN
cord-009417-458rrhcm	740	10	and	and	CC
cord-009417-458rrhcm	740	11	patient	patient	NNP
cord-009417-458rrhcm	740	12	identifi	identifi	NNP
cord-009417-458rrhcm	740	13	cation	cation	NN
cord-009417-458rrhcm	740	14	procedures	procedure	NNS
cord-009417-458rrhcm	740	15	.	.	.
cord-009417-458rrhcm	741	1	■	■	NFP
cord-009417-458rrhcm	741	2	Transmission	transmission	NN
cord-009417-458rrhcm	741	3	of	of	IN
cord-009417-458rrhcm	741	4	infectious	infectious	JJ
cord-009417-458rrhcm	741	5	agents	agent	NNS
cord-009417-458rrhcm	741	6	by	by	IN
cord-009417-458rrhcm	741	7	transfusion	transfusion	NN
cord-009417-458rrhcm	741	8	has	have	VBZ
cord-009417-458rrhcm	741	9	been	be	VBN
cord-009417-458rrhcm	741	10	markedly	markedly	RB
cord-009417-458rrhcm	741	11	reduced	reduce	VBN
cord-009417-458rrhcm	741	12	,	,	,
cord-009417-458rrhcm	741	13	and	and	CC
cord-009417-458rrhcm	741	14	bacterial	bacterial	JJ
cord-009417-458rrhcm	741	15	infection	infection	NN
cord-009417-458rrhcm	741	16	is	be	VBZ
cord-009417-458rrhcm	741	17	now	now	RB
cord-009417-458rrhcm	741	18	the	the	DT
cord-009417-458rrhcm	741	19	most	most	RBS
cord-009417-458rrhcm	741	20	common	common	JJ
cord-009417-458rrhcm	741	21	infectious	infectious	JJ
cord-009417-458rrhcm	741	22	complication	complication	NN
cord-009417-458rrhcm	741	23	of	of	IN
cord-009417-458rrhcm	741	24	transfusion	transfusion	NN
cord-009417-458rrhcm	741	25	.	.	.
cord-009417-458rrhcm	742	1	■	■	NFP
cord-009417-458rrhcm	742	2	Adverse	adverse	JJ
cord-009417-458rrhcm	742	3	effects	effect	NNS
cord-009417-458rrhcm	742	4	unique	unique	JJ
cord-009417-458rrhcm	742	5	to	to	IN
cord-009417-458rrhcm	742	6	massive	massive	JJ
cord-009417-458rrhcm	742	7	transfusion	transfusion	NN
cord-009417-458rrhcm	742	8	are	be	VBP
cord-009417-458rrhcm	742	9	likely	likely	JJ
cord-009417-458rrhcm	742	10	to	to	TO
cord-009417-458rrhcm	742	11	occur	occur	VB
cord-009417-458rrhcm	742	12	in	in	IN
cord-009417-458rrhcm	742	13	the	the	DT
cord-009417-458rrhcm	742	14	ICU	ICU	NNP
cord-009417-458rrhcm	742	15	and	and	CC
cord-009417-458rrhcm	742	16	complicate	complicate	VB
cord-009417-458rrhcm	742	17	the	the	DT
cord-009417-458rrhcm	742	18	management	management	NN
cord-009417-458rrhcm	742	19	of	of	IN
cord-009417-458rrhcm	742	20	critically	critically	RB
cord-009417-458rrhcm	742	21	ill	ill	JJ
cord-009417-458rrhcm	742	22	or	or	CC
cord-009417-458rrhcm	742	23	severely	severely	RB
cord-009417-458rrhcm	742	24	injured	injure	VBN
cord-009417-458rrhcm	742	25	patients	patient	NNS
cord-009417-458rrhcm	742	26	.	.	.
cord-009417-458rrhcm	743	1	Component	component	NN
cord-009417-458rrhcm	743	2	therapy	therapy	NN
cord-009417-458rrhcm	743	3	for	for	IN
cord-009417-458rrhcm	743	4	such	such	JJ
cord-009417-458rrhcm	743	5	patients	patient	NNS
cord-009417-458rrhcm	743	6	should	should	MD
cord-009417-458rrhcm	743	7	remain	remain	VB
cord-009417-458rrhcm	743	8	conservative	conservative	JJ
cord-009417-458rrhcm	743	9	.	.	.
cord-009417-458rrhcm	744	1	The	the	DT
cord-009417-458rrhcm	744	2	emerging	emerge	VBG
cord-009417-458rrhcm	744	3	role	role	NN
cord-009417-458rrhcm	744	4	of	of	IN
cord-009417-458rrhcm	744	5	activated	activate	VBN
cord-009417-458rrhcm	744	6	factor	factor	NN
cord-009417-458rrhcm	744	7	VII	vii	NN
cord-009417-458rrhcm	744	8	in	in	IN
cord-009417-458rrhcm	744	9	the	the	DT
cord-009417-458rrhcm	744	10	treatment	treatment	NN
cord-009417-458rrhcm	744	11	of	of	IN
cord-009417-458rrhcm	744	12	these	these	DT
cord-009417-458rrhcm	744	13	patients	patient	NNS
cord-009417-458rrhcm	744	14	requires	require	VBZ
cord-009417-458rrhcm	744	15	further	further	JJ
cord-009417-458rrhcm	744	16	evaluation	evaluation	NN
cord-009417-458rrhcm	744	17	.	.	.
cord-009417-458rrhcm	745	1	■	■	NFP
cord-009417-458rrhcm	745	2	Informed	Informed	NNP
cord-009417-458rrhcm	745	3	consent	consent	NN
cord-009417-458rrhcm	745	4	for	for	IN
cord-009417-458rrhcm	745	5	blood	blood	NN
cord-009417-458rrhcm	745	6	transfusion	transfusion	NN
cord-009417-458rrhcm	745	7	is	be	VBZ
cord-009417-458rrhcm	745	8	a	a	DT
cord-009417-458rrhcm	745	9	standard	standard	NN
cord-009417-458rrhcm	745	10	of	of	IN
cord-009417-458rrhcm	745	11	practice	practice	NN
cord-009417-458rrhcm	745	12	.	.	.
cord-009417-458rrhcm	746	1	A	a	DT
cord-009417-458rrhcm	746	2	competent	competent	JJ
cord-009417-458rrhcm	746	3	adult	adult	NN
cord-009417-458rrhcm	746	4	has	have	VBZ
cord-009417-458rrhcm	746	5	the	the	DT
cord-009417-458rrhcm	746	6	legal	legal	JJ
cord-009417-458rrhcm	746	7	right	right	NN
cord-009417-458rrhcm	746	8	to	to	TO
cord-009417-458rrhcm	746	9	refuse	refuse	VB
cord-009417-458rrhcm	746	10	blood	blood	NN
cord-009417-458rrhcm	746	11	transfusion	transfusion	NN
cord-009417-458rrhcm	746	12	.	.	.
cord-009417-458rrhcm	747	1	Consent	consent	VB
cord-009417-458rrhcm	747	2	in	in	IN
cord-009417-458rrhcm	747	3	critically	critically	RB
cord-009417-458rrhcm	747	4	ill	ill	JJ
cord-009417-458rrhcm	747	5	patients	patient	NNS
cord-009417-458rrhcm	747	6	remains	remain	VBZ
cord-009417-458rrhcm	747	7	subject	subject	JJ
cord-009417-458rrhcm	747	8	to	to	IN
cord-009417-458rrhcm	747	9	individual	individual	JJ
cord-009417-458rrhcm	747	10	institution	institution	NN
cord-009417-458rrhcm	747	11	policies	policy	NNS
cord-009417-458rrhcm	747	12	.	.	.
cord-009417-458rrhcm	748	1	Department	Department	NNP
cord-009417-458rrhcm	748	2	of	of	IN
cord-009417-458rrhcm	748	3	Health	Health	NNP
cord-009417-458rrhcm	748	4	and	and	CC
cord-009417-458rrhcm	748	5	Human	Human	NNP
cord-009417-458rrhcm	748	6	Services	Services	NNPS
cord-009417-458rrhcm	748	7	,	,	,
cord-009417-458rrhcm	748	8	Food	Food	NNP
cord-009417-458rrhcm	748	9	and	and	CC
cord-009417-458rrhcm	748	10	Drug	Drug	NNP
cord-009417-458rrhcm	748	11	Administration	Administration	NNP
cord-009417-458rrhcm	748	12	:	:	:
cord-009417-458rrhcm	749	1	The	the	DT
cord-009417-458rrhcm	749	2	Code	Code	NNP
cord-009417-458rrhcm	749	3	of	of	IN
cord-009417-458rrhcm	749	4	Federal	Federal	NNP
cord-009417-458rrhcm	749	5	Regulations	Regulations	NNPS
cord-009417-458rrhcm	749	6	,	,	,
cord-009417-458rrhcm	749	7	21	21	CD
cord-009417-458rrhcm	749	8	CFR	CFR	NNP
cord-009417-458rrhcm	749	9	Parts	Parts	NNPS
cord-009417-458rrhcm	749	10	600	600	CD
cord-009417-458rrhcm	749	11	,	,	,
cord-009417-458rrhcm	749	12	606	606	CD
cord-009417-458rrhcm	749	13	,	,	,
cord-009417-458rrhcm	749	14	640	640	CD
cord-009417-458rrhcm	749	15	Standards	Standards	NNPS
cord-009417-458rrhcm	749	16	for	for	IN
cord-009417-458rrhcm	749	17	Blood	blood	NN
cord-009417-458rrhcm	749	18	Banks	Banks	NNPS
cord-009417-458rrhcm	749	19	and	and	CC
cord-009417-458rrhcm	749	20	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	749	21	Services	Services	NNPS
cord-009417-458rrhcm	749	22	Markers	Markers	NNPS
cord-009417-458rrhcm	749	23	for	for	IN
cord-009417-458rrhcm	749	24	transfusiontransmitted	transfusiontransmitted	JJ
cord-009417-458rrhcm	749	25	disease	disease	NN
cord-009417-458rrhcm	749	26	in	in	IN
cord-009417-458rrhcm	749	27	different	different	JJ
cord-009417-458rrhcm	749	28	groups	group	NNS
cord-009417-458rrhcm	749	29	of	of	IN
cord-009417-458rrhcm	749	30	blood	blood	NN
cord-009417-458rrhcm	749	31	donors	donor	NNS
cord-009417-458rrhcm	749	32	Comparative	comparative	JJ
cord-009417-458rrhcm	749	33	safety	safety	NN
cord-009417-458rrhcm	749	34	of	of	IN
cord-009417-458rrhcm	749	35	units	unit	NNS
cord-009417-458rrhcm	749	36	donated	donate	VBN
cord-009417-458rrhcm	749	37	by	by	IN
cord-009417-458rrhcm	749	38	autologous	autologous	JJ
cord-009417-458rrhcm	749	39	,	,	,
cord-009417-458rrhcm	749	40	designated	designated	JJ
cord-009417-458rrhcm	749	41	and	and	CC
cord-009417-458rrhcm	749	42	allogeneic	allogeneic	JJ
cord-009417-458rrhcm	749	43	(	(	-LRB-
cord-009417-458rrhcm	749	44	homologous	homologous	JJ
cord-009417-458rrhcm	749	45	)	)	-RRB-
cord-009417-458rrhcm	749	46	donors	donor	NNS
cord-009417-458rrhcm	749	47	Directed	direct	VBD
cord-009417-458rrhcm	749	48	blood	blood	NN
cord-009417-458rrhcm	749	49	donations	donation	NNS
cord-009417-458rrhcm	749	50	:	:	:
cord-009417-458rrhcm	749	51	Con	Con	NNP
cord-009417-458rrhcm	749	52	Goldfi	Goldfi	NNP
cord-009417-458rrhcm	749	53	nger	nger	NN
cord-009417-458rrhcm	749	54	D	d	NN
cord-009417-458rrhcm	749	55	:	:	:
cord-009417-458rrhcm	749	56	Directed	direct	VBN
cord-009417-458rrhcm	749	57	blood	blood	NN
cord-009417-458rrhcm	749	58	donations	donation	NNS
cord-009417-458rrhcm	749	59	:	:	:
cord-009417-458rrhcm	749	60	Pro	Pro	NNP
cord-009417-458rrhcm	749	61	Shelf	Shelf	NNP
cord-009417-458rrhcm	749	62	-	-	HYPH
cord-009417-458rrhcm	749	63	life	life	NN
cord-009417-458rrhcm	749	64	of	of	IN
cord-009417-458rrhcm	749	65	bank	bank	NN
cord-009417-458rrhcm	749	66	blood	blood	NN
cord-009417-458rrhcm	749	67	and	and	CC
cord-009417-458rrhcm	749	68	stored	store	VBD
cord-009417-458rrhcm	749	69	plasma	plasma	NN
cord-009417-458rrhcm	749	70	with	with	IN
cord-009417-458rrhcm	749	71	special	special	JJ
cord-009417-458rrhcm	749	72	reference	reference	NN
cord-009417-458rrhcm	749	73	to	to	IN
cord-009417-458rrhcm	749	74	coagulation	coagulation	NN
cord-009417-458rrhcm	749	75	factors	factor	NNS
cord-009417-458rrhcm	750	1	Generation	generation	NN
cord-009417-458rrhcm	750	2	of	of	IN
cord-009417-458rrhcm	750	3	cytokines	cytokine	NNS
cord-009417-458rrhcm	750	4	in	in	IN
cord-009417-458rrhcm	750	5	red	red	JJ
cord-009417-458rrhcm	750	6	cell	cell	NN
cord-009417-458rrhcm	750	7	concentrates	concentrate	VBZ
cord-009417-458rrhcm	750	8	during	during	IN
cord-009417-458rrhcm	750	9	storage	storage	NN
cord-009417-458rrhcm	750	10	is	be	VBZ
cord-009417-458rrhcm	750	11	prevented	prevent	VBN
cord-009417-458rrhcm	750	12	by	by	IN
cord-009417-458rrhcm	750	13	prestorage	prestorage	JJ
cord-009417-458rrhcm	750	14	white	white	JJ
cord-009417-458rrhcm	750	15	cell	cell	NN
cord-009417-458rrhcm	750	16	reduction	reduction	NN
cord-009417-458rrhcm	750	17	Universal	Universal	NNP
cord-009417-458rrhcm	750	18	WBC	WBC	NNP
cord-009417-458rrhcm	750	19	reduction	reduction	NN
cord-009417-458rrhcm	750	20	:	:	:
cord-009417-458rrhcm	750	21	The	the	DT
cord-009417-458rrhcm	750	22	case	case	NN
cord-009417-458rrhcm	750	23	for	for	IN
cord-009417-458rrhcm	750	24	and	and	CC
cord-009417-458rrhcm	750	25	against	against	IN
cord-009417-458rrhcm	750	26	Chemical	Chemical	NNP
cord-009417-458rrhcm	750	27	and	and	CC
cord-009417-458rrhcm	750	28	hematological	hematological	JJ
cord-009417-458rrhcm	750	29	changes	change	NNS
cord-009417-458rrhcm	750	30	in	in	IN
cord-009417-458rrhcm	750	31	stored	store	VBN
cord-009417-458rrhcm	750	32	CPDA-1	CPDA-1	NNP
cord-009417-458rrhcm	750	33	blood	blood	NN
cord-009417-458rrhcm	750	34	Restoration	restoration	NN
cord-009417-458rrhcm	750	35	in	in	IN
cord-009417-458rrhcm	750	36	vitro	vitro	FW
cord-009417-458rrhcm	750	37	of	of	IN
cord-009417-458rrhcm	750	38	erythrocyte	erythrocyte	NN
cord-009417-458rrhcm	750	39	adenosine	adenosine	NN
cord-009417-458rrhcm	750	40	triphosphate	triphosphate	NN
cord-009417-458rrhcm	750	41	,	,	,
cord-009417-458rrhcm	750	42	2,3-diphosphoglycerate	2,3-diphosphoglycerate	CD
cord-009417-458rrhcm	750	43	,	,	,
cord-009417-458rrhcm	750	44	potassium	potassium	NN
cord-009417-458rrhcm	750	45	ion	ion	NN
cord-009417-458rrhcm	750	46	,	,	,
cord-009417-458rrhcm	750	47	and	and	CC
cord-009417-458rrhcm	750	48	sodium	sodium	NN
cord-009417-458rrhcm	750	49	ion	ion	NN
cord-009417-458rrhcm	750	50	concentrations	concentration	NNS
cord-009417-458rrhcm	750	51	following	follow	VBG
cord-009417-458rrhcm	750	52	the	the	DT
cord-009417-458rrhcm	750	53	transfusion	transfusion	NN
cord-009417-458rrhcm	750	54	of	of	IN
cord-009417-458rrhcm	750	55	acid	acid	NN
cord-009417-458rrhcm	750	56	-	-	HYPH
cord-009417-458rrhcm	750	57	citrate	citrate	NN
cord-009417-458rrhcm	750	58	-	-	HYPH
cord-009417-458rrhcm	750	59	dextrose	dextrose	NN
cord-009417-458rrhcm	750	60	stored	store	VBN
cord-009417-458rrhcm	750	61	human	human	JJ
cord-009417-458rrhcm	750	62	red	red	JJ
cord-009417-458rrhcm	750	63	blood	blood	NN
cord-009417-458rrhcm	750	64	cells	cell	NNS
cord-009417-458rrhcm	750	65	Comparison	comparison	NN
cord-009417-458rrhcm	750	66	of	of	IN
cord-009417-458rrhcm	750	67	the	the	DT
cord-009417-458rrhcm	750	68	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	750	69	effects	effect	NNS
cord-009417-458rrhcm	750	70	of	of	IN
cord-009417-458rrhcm	750	71	fresh	fresh	JJ
cord-009417-458rrhcm	750	72	whole	whole	JJ
cord-009417-458rrhcm	750	73	blood	blood	NN
cord-009417-458rrhcm	750	74	,	,	,
cord-009417-458rrhcm	750	75	stored	store	VBD
cord-009417-458rrhcm	750	76	whole	whole	JJ
cord-009417-458rrhcm	750	77	blood	blood	NN
cord-009417-458rrhcm	750	78	,	,	,
cord-009417-458rrhcm	750	79	and	and	CC
cord-009417-458rrhcm	750	80	components	component	NNS
cord-009417-458rrhcm	750	81	after	after	IN
cord-009417-458rrhcm	750	82	open	open	JJ
cord-009417-458rrhcm	750	83	heart	heart	NN
cord-009417-458rrhcm	750	84	surgery	surgery	NN
cord-009417-458rrhcm	750	85	in	in	IN
cord-009417-458rrhcm	750	86	children	child	NNS
cord-009417-458rrhcm	751	1	A	a	DT
cord-009417-458rrhcm	751	2	practice	practice	NN
cord-009417-458rrhcm	751	3	guideline	guideline	NN
cord-009417-458rrhcm	751	4	and	and	CC
cord-009417-458rrhcm	751	5	decision	decision	NN
cord-009417-458rrhcm	751	6	aide	aide	NN
cord-009417-458rrhcm	751	7	for	for	IN
cord-009417-458rrhcm	751	8	blood	blood	NN
cord-009417-458rrhcm	751	9	transfusion	transfusion	NN
cord-009417-458rrhcm	751	10	RBC	RBC	NNP
cord-009417-458rrhcm	751	11	transfusion	transfusion	NN
cord-009417-458rrhcm	751	12	in	in	IN
cord-009417-458rrhcm	751	13	the	the	DT
cord-009417-458rrhcm	751	14	ICU	ICU	NNP
cord-009417-458rrhcm	752	1	:	:	:
cord-009417-458rrhcm	752	2	Is	be	VBZ
cord-009417-458rrhcm	752	3	there	there	EX
cord-009417-458rrhcm	752	4	a	a	DT
cord-009417-458rrhcm	752	5	reason	reason	NN
cord-009417-458rrhcm	752	6	?	?	.
cord-009417-458rrhcm	753	1	Descriptive	descriptive	JJ
cord-009417-458rrhcm	753	2	analysis	analysis	NN
cord-009417-458rrhcm	753	3	of	of	IN
cord-009417-458rrhcm	753	4	critical	critical	JJ
cord-009417-458rrhcm	753	5	care	care	NN
cord-009417-458rrhcm	753	6	units	unit	NNS
cord-009417-458rrhcm	753	7	in	in	IN
cord-009417-458rrhcm	753	8	the	the	DT
cord-009417-458rrhcm	753	9	United	United	NNP
cord-009417-458rrhcm	753	10	States	States	NNP
cord-009417-458rrhcm	753	11	:	:	:
cord-009417-458rrhcm	753	12	Patient	patient	JJ
cord-009417-458rrhcm	753	13	characteristics	characteristic	NNS
cord-009417-458rrhcm	753	14	and	and	CC
cord-009417-458rrhcm	753	15	intensive	intensive	JJ
cord-009417-458rrhcm	753	16	care	care	NN
cord-009417-458rrhcm	753	17	unit	unit	NN
cord-009417-458rrhcm	753	18	utilization	utilization	NN
cord-009417-458rrhcm	753	19	Oxygen	Oxygen	NNP
cord-009417-458rrhcm	753	20	transport	transport	NN
cord-009417-458rrhcm	753	21	in	in	IN
cord-009417-458rrhcm	753	22	man	man	NN
cord-009417-458rrhcm	753	23	Physiologic	physiologic	JJ
cord-009417-458rrhcm	753	24	aspects	aspect	NNS
cord-009417-458rrhcm	753	25	of	of	IN
cord-009417-458rrhcm	753	26	anemia	anemia	NN
cord-009417-458rrhcm	753	27	Oxygen	oxygen	NN
cord-009417-458rrhcm	753	28	extraction	extraction	NN
cord-009417-458rrhcm	753	29	ratio	ratio	NN
cord-009417-458rrhcm	753	30	:	:	:
cord-009417-458rrhcm	753	31	A	a	DT
cord-009417-458rrhcm	753	32	valid	valid	JJ
cord-009417-458rrhcm	753	33	indicator	indicator	NN
cord-009417-458rrhcm	753	34	of	of	IN
cord-009417-458rrhcm	753	35	myocardial	myocardial	JJ
cord-009417-458rrhcm	753	36	metabolism	metabolism	NN
cord-009417-458rrhcm	753	37	in	in	IN
cord-009417-458rrhcm	753	38	anemia	anemia	NN
cord-009417-458rrhcm	753	39	Human	Human	NNP
cord-009417-458rrhcm	753	40	cardiovascular	cardiovascular	NN
cord-009417-458rrhcm	753	41	and	and	CC
cord-009417-458rrhcm	753	42	metabolic	metabolic	JJ
cord-009417-458rrhcm	753	43	response	response	NN
cord-009417-458rrhcm	753	44	to	to	IN
cord-009417-458rrhcm	753	45	acute	acute	JJ
cord-009417-458rrhcm	753	46	,	,	,
cord-009417-458rrhcm	753	47	severe	severe	JJ
cord-009417-458rrhcm	753	48	isovolemic	isovolemic	JJ
cord-009417-458rrhcm	753	49	anemia	anemia	NN
cord-009417-458rrhcm	753	50	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	753	51	guidelines	guideline	NNS
cord-009417-458rrhcm	753	52	for	for	IN
cord-009417-458rrhcm	753	53	cardiovascular	cardiovascular	JJ
cord-009417-458rrhcm	753	54	surgery	surgery	NN
cord-009417-458rrhcm	753	55	:	:	:
cord-009417-458rrhcm	753	56	Lessons	lesson	NNS
cord-009417-458rrhcm	753	57	learned	learn	VBD
cord-009417-458rrhcm	753	58	from	from	IN
cord-009417-458rrhcm	753	59	operations	operation	NNS
cord-009417-458rrhcm	753	60	in	in	IN
cord-009417-458rrhcm	753	61	Jehovah	Jehovah	NNP
cord-009417-458rrhcm	753	62	's	's	POS
cord-009417-458rrhcm	753	63	Witnesses	Witnesses	NNPS
cord-009417-458rrhcm	753	64	Physiologic	physiologic	JJ
cord-009417-458rrhcm	753	65	effects	effect	NNS
cord-009417-458rrhcm	753	66	of	of	IN
cord-009417-458rrhcm	753	67	acute	acute	JJ
cord-009417-458rrhcm	753	68	anemia	anemia	NN
cord-009417-458rrhcm	753	69	:	:	:
cord-009417-458rrhcm	753	70	Implications	implication	NNS
cord-009417-458rrhcm	753	71	for	for	IN
cord-009417-458rrhcm	753	72	a	a	DT
cord-009417-458rrhcm	753	73	reduced	reduce	VBN
cord-009417-458rrhcm	753	74	transfusion	transfusion	NN
cord-009417-458rrhcm	753	75	trigger	trigger	NN
cord-009417-458rrhcm	753	76	A	a	DT
cord-009417-458rrhcm	753	77	multicenter	multicenter	NN
cord-009417-458rrhcm	753	78	,	,	,
cord-009417-458rrhcm	753	79	randomized	randomized	JJ
cord-009417-458rrhcm	753	80	,	,	,
cord-009417-458rrhcm	753	81	controlled	control	VBN
cord-009417-458rrhcm	753	82	clinical	clinical	JJ
cord-009417-458rrhcm	753	83	trial	trial	NN
cord-009417-458rrhcm	753	84	of	of	IN
cord-009417-458rrhcm	753	85	transfusion	transfusion	NN
cord-009417-458rrhcm	753	86	requirements	requirement	NNS
cord-009417-458rrhcm	753	87	in	in	IN
cord-009417-458rrhcm	753	88	critical	critical	JJ
cord-009417-458rrhcm	753	89	care	care	NN
cord-009417-458rrhcm	754	1	Is	be	VBZ
cord-009417-458rrhcm	754	2	a	a	DT
cord-009417-458rrhcm	754	3	low	low	JJ
cord-009417-458rrhcm	754	4	transfusion	transfusion	NN
cord-009417-458rrhcm	754	5	threshold	threshold	NN
cord-009417-458rrhcm	754	6	safe	safe	JJ
cord-009417-458rrhcm	754	7	in	in	IN
cord-009417-458rrhcm	754	8	critically	critically	RB
cord-009417-458rrhcm	754	9	ill	ill	JJ
cord-009417-458rrhcm	754	10	patients	patient	NNS
cord-009417-458rrhcm	754	11	with	with	IN
cord-009417-458rrhcm	754	12	cardiovascular	cardiovascular	JJ
cord-009417-458rrhcm	754	13	diseases	disease	NNS
cord-009417-458rrhcm	754	14	?	?	.
cord-009417-458rrhcm	755	1	Oxygen	oxygen	NN
cord-009417-458rrhcm	755	2	extraction	extraction	NN
cord-009417-458rrhcm	755	3	ratio	ratio	NN
cord-009417-458rrhcm	755	4	:	:	:
cord-009417-458rrhcm	755	5	A	a	DT
cord-009417-458rrhcm	755	6	valid	valid	JJ
cord-009417-458rrhcm	755	7	indicator	indicator	NN
cord-009417-458rrhcm	755	8	of	of	IN
cord-009417-458rrhcm	755	9	transfusion	transfusion	NN
cord-009417-458rrhcm	755	10	need	need	NN
cord-009417-458rrhcm	755	11	in	in	IN
cord-009417-458rrhcm	755	12	limited	limited	JJ
cord-009417-458rrhcm	755	13	coronary	coronary	JJ
cord-009417-458rrhcm	755	14	vascular	vascular	JJ
cord-009417-458rrhcm	755	15	reserve	reserve	NN
cord-009417-458rrhcm	755	16	?	?	.
cord-009417-458rrhcm	756	1	for	for	IN
cord-009417-458rrhcm	756	2	the	the	DT
cord-009417-458rrhcm	756	3	ABC	ABC	NNP
cord-009417-458rrhcm	756	4	Investigators	investigator	NNS
cord-009417-458rrhcm	756	5	:	:	:
cord-009417-458rrhcm	756	6	Anemia	anemia	NN
cord-009417-458rrhcm	756	7	and	and	CC
cord-009417-458rrhcm	756	8	blood	blood	NN
cord-009417-458rrhcm	756	9	transfusion	transfusion	NN
cord-009417-458rrhcm	756	10	in	in	IN
cord-009417-458rrhcm	756	11	critically	critically	RB
cord-009417-458rrhcm	756	12	ill	ill	JJ
cord-009417-458rrhcm	756	13	patients	patient	NNS
cord-009417-458rrhcm	757	1	The	the	DT
cord-009417-458rrhcm	757	2	CRIT	crit	NN
cord-009417-458rrhcm	757	3	study	study	NN
cord-009417-458rrhcm	757	4	:	:	:
cord-009417-458rrhcm	757	5	Anemia	anemia	NN
cord-009417-458rrhcm	757	6	and	and	CC
cord-009417-458rrhcm	757	7	blood	blood	NN
cord-009417-458rrhcm	757	8	transfusion	transfusion	NN
cord-009417-458rrhcm	757	9	in	in	IN
cord-009417-458rrhcm	757	10	the	the	DT
cord-009417-458rrhcm	757	11	critically	critically	RB
cord-009417-458rrhcm	757	12	ill	ill	JJ
cord-009417-458rrhcm	757	13	-	-	HYPH
cord-009417-458rrhcm	757	14	current	current	JJ
cord-009417-458rrhcm	757	15	clinical	clinical	JJ
cord-009417-458rrhcm	757	16	practice	practice	NN
cord-009417-458rrhcm	757	17	in	in	IN
cord-009417-458rrhcm	757	18	the	the	DT
cord-009417-458rrhcm	757	19	United	United	NNP
cord-009417-458rrhcm	757	20	States	States	NNP
cord-009417-458rrhcm	757	21	Red	Red	NNP
cord-009417-458rrhcm	757	22	cell	cell	NN
cord-009417-458rrhcm	757	23	transfusion	transfusion	NN
cord-009417-458rrhcm	757	24	practice	practice	NN
cord-009417-458rrhcm	757	25	following	follow	VBG
cord-009417-458rrhcm	757	26	the	the	DT
cord-009417-458rrhcm	757	27	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	757	28	Requirements	requirement	NNS
cord-009417-458rrhcm	757	29	in	in	IN
cord-009417-458rrhcm	757	30	Critical	Critical	NNP
cord-009417-458rrhcm	757	31	Care	Care	NNP
cord-009417-458rrhcm	758	1	(	(	-LRB-
cord-009417-458rrhcm	758	2	TRICC	TRICC	NNP
cord-009417-458rrhcm	758	3	)	)	-RRB-
cord-009417-458rrhcm	758	4	study	study	NN
cord-009417-458rrhcm	758	5	:	:	:
cord-009417-458rrhcm	759	1	Prospective	prospective	JJ
cord-009417-458rrhcm	759	2	observational	observational	JJ
cord-009417-458rrhcm	759	3	cohort	cohort	NN
cord-009417-458rrhcm	759	4	study	study	NN
cord-009417-458rrhcm	759	5	in	in	IN
cord-009417-458rrhcm	759	6	a	a	DT
cord-009417-458rrhcm	759	7	large	large	JJ
cord-009417-458rrhcm	759	8	UK	UK	NNP
cord-009417-458rrhcm	759	9	intensive	intensive	JJ
cord-009417-458rrhcm	759	10	care	care	NN
cord-009417-458rrhcm	759	11	unit	unit	NN
cord-009417-458rrhcm	759	12	Appropriateness	appropriateness	NN
cord-009417-458rrhcm	759	13	of	of	IN
cord-009417-458rrhcm	759	14	red	red	JJ
cord-009417-458rrhcm	759	15	blood	blood	NN
cord-009417-458rrhcm	759	16	cell	cell	NN
cord-009417-458rrhcm	759	17	transfusion	transfusion	NN
cord-009417-458rrhcm	759	18	in	in	IN
cord-009417-458rrhcm	759	19	Australasian	australasian	JJ
cord-009417-458rrhcm	759	20	intensive	intensive	JJ
cord-009417-458rrhcm	759	21	care	care	NN
cord-009417-458rrhcm	759	22	practice	practice	NN
cord-009417-458rrhcm	760	1	Silent	silent	JJ
cord-009417-458rrhcm	760	2	myocardial	myocardial	JJ
cord-009417-458rrhcm	760	3	ischaemia	ischaemia	NN
cord-009417-458rrhcm	760	4	and	and	CC
cord-009417-458rrhcm	760	5	haemoglobin	haemoglobin	NN
cord-009417-458rrhcm	760	6	concentration	concentration	NN
cord-009417-458rrhcm	760	7	:	:	:
cord-009417-458rrhcm	761	1	A	a	DT
cord-009417-458rrhcm	761	2	randomized	randomized	JJ
cord-009417-458rrhcm	761	3	controlled	control	VBN
cord-009417-458rrhcm	761	4	trial	trial	NN
cord-009417-458rrhcm	761	5	of	of	IN
cord-009417-458rrhcm	761	6	transfusion	transfusion	NN
cord-009417-458rrhcm	761	7	strategy	strategy	NN
cord-009417-458rrhcm	761	8	in	in	IN
cord-009417-458rrhcm	761	9	lower	low	JJR
cord-009417-458rrhcm	761	10	limb	limb	NN
cord-009417-458rrhcm	761	11	arthroplasty	arthroplasty	NNP
cord-009417-458rrhcm	762	1	Mathematical	mathematical	JJ
cord-009417-458rrhcm	762	2	analysis	analysis	NN
cord-009417-458rrhcm	762	3	of	of	IN
cord-009417-458rrhcm	762	4	isovolemic	isovolemic	NNP
cord-009417-458rrhcm	762	5	hemodilution	hemodilution	NNP
cord-009417-458rrhcm	762	6	indicates	indicate	VBZ
cord-009417-458rrhcm	762	7	that	that	IN
cord-009417-458rrhcm	762	8	it	-PRON-	PRP
cord-009417-458rrhcm	762	9	can	can	MD
cord-009417-458rrhcm	762	10	decrease	decrease	VB
cord-009417-458rrhcm	762	11	the	the	DT
cord-009417-458rrhcm	762	12	need	need	NN
cord-009417-458rrhcm	762	13	for	for	IN
cord-009417-458rrhcm	762	14	allogeneic	allogeneic	VBG
cord-009417-458rrhcm	762	15	blood	blood	NN
cord-009417-458rrhcm	762	16	transfusion	transfusion	NN
cord-009417-458rrhcm	762	17	Guidelines	guideline	NNS
cord-009417-458rrhcm	762	18	for	for	IN
cord-009417-458rrhcm	762	19	perioperative	perioperative	JJ
cord-009417-458rrhcm	762	20	red	red	JJ
cord-009417-458rrhcm	762	21	blood	blood	NN
cord-009417-458rrhcm	762	22	cell	cell	NN
cord-009417-458rrhcm	762	23	transfusions	transfusion	NNS
cord-009417-458rrhcm	762	24	American	American	NNP
cord-009417-458rrhcm	762	25	Society	Society	NNP
cord-009417-458rrhcm	762	26	of	of	IN
cord-009417-458rrhcm	762	27	Anesthesiologists	Anesthesiologists	NNP
cord-009417-458rrhcm	762	28	Task	Task	NNP
cord-009417-458rrhcm	762	29	Force	Force	NNP
cord-009417-458rrhcm	762	30	:	:	:
cord-009417-458rrhcm	762	31	Practice	practice	VB
cord-009417-458rrhcm	762	32	guidelines	guideline	NNS
cord-009417-458rrhcm	762	33	for	for	IN
cord-009417-458rrhcm	762	34	blood	blood	NN
cord-009417-458rrhcm	762	35	component	component	NN
cord-009417-458rrhcm	762	36	therapy	therapy	NN
cord-009417-458rrhcm	762	37	Prudent	Prudent	NNP
cord-009417-458rrhcm	762	38	strategies	strategy	NNS
cord-009417-458rrhcm	762	39	for	for	IN
cord-009417-458rrhcm	762	40	elective	elective	JJ
cord-009417-458rrhcm	762	41	red	red	JJ
cord-009417-458rrhcm	762	42	blood	blood	NN
cord-009417-458rrhcm	762	43	cell	cell	NN
cord-009417-458rrhcm	762	44	transfusion	transfusion	NN
cord-009417-458rrhcm	762	45	Platelet	platelet	NN
cord-009417-458rrhcm	762	46	transfusion	transfusion	NN
cord-009417-458rrhcm	762	47	therapy	therapy	NN
cord-009417-458rrhcm	762	48	.	.	.
cord-009417-458rrhcm	763	1	Onehour	onehour	JJ
cord-009417-458rrhcm	763	2	posttransfusion	posttransfusion	NN
cord-009417-458rrhcm	763	3	increments	increment	NNS
cord-009417-458rrhcm	763	4	are	be	VBP
cord-009417-458rrhcm	763	5	valuable	valuable	JJ
cord-009417-458rrhcm	763	6	in	in	IN
cord-009417-458rrhcm	763	7	predicting	predict	VBG
cord-009417-458rrhcm	763	8	the	the	DT
cord-009417-458rrhcm	763	9	need	need	NN
cord-009417-458rrhcm	763	10	for	for	IN
cord-009417-458rrhcm	763	11	HLA	HLA	NNP
cord-009417-458rrhcm	763	12	-	-	HYPH
cord-009417-458rrhcm	763	13	matched	match	VBN
cord-009417-458rrhcm	763	14	preparations	preparation	NNS
cord-009417-458rrhcm	763	15	Volunteer	Volunteer	NNP
cord-009417-458rrhcm	763	16	donor	donor	NN
cord-009417-458rrhcm	763	17	apheresis	apheresis	NN
cord-009417-458rrhcm	763	18	National	National	NNP
cord-009417-458rrhcm	763	19	Institutes	Institutes	NNPS
cord-009417-458rrhcm	763	20	of	of	IN
cord-009417-458rrhcm	763	21	Health	Health	NNP
cord-009417-458rrhcm	763	22	Consensus	Consensus	NNP
cord-009417-458rrhcm	763	23	Conference	Conference	NNP
cord-009417-458rrhcm	763	24	:	:	:
cord-009417-458rrhcm	763	25	Platelet	platelet	NN
cord-009417-458rrhcm	763	26	transfusion	transfusion	NN
cord-009417-458rrhcm	763	27	therapy	therapy	NN
cord-009417-458rrhcm	764	1	The	the	DT
cord-009417-458rrhcm	764	2	bleeding	bleeding	JJ
cord-009417-458rrhcm	764	3	time	time	NN
cord-009417-458rrhcm	764	4	as	as	IN
cord-009417-458rrhcm	764	5	a	a	DT
cord-009417-458rrhcm	764	6	screening	screening	NN
cord-009417-458rrhcm	764	7	test	test	NN
cord-009417-458rrhcm	764	8	for	for	IN
cord-009417-458rrhcm	764	9	evaluation	evaluation	NN
cord-009417-458rrhcm	764	10	of	of	IN
cord-009417-458rrhcm	764	11	platelet	platelet	NN
cord-009417-458rrhcm	764	12	function	function	NN
cord-009417-458rrhcm	764	13	Changes	change	NNS
cord-009417-458rrhcm	764	14	in	in	IN
cord-009417-458rrhcm	764	15	blood	blood	NN
cord-009417-458rrhcm	764	16	coagulation	coagulation	NN
cord-009417-458rrhcm	764	17	during	during	IN
cord-009417-458rrhcm	764	18	and	and	CC
cord-009417-458rrhcm	764	19	following	follow	VBG
cord-009417-458rrhcm	764	20	cardiopulmonary	cardiopulmonary	JJ
cord-009417-458rrhcm	764	21	bypass	bypass	NN
cord-009417-458rrhcm	765	1	:	:	:
cord-009417-458rrhcm	765	2	Lack	lack	NN
cord-009417-458rrhcm	765	3	of	of	IN
cord-009417-458rrhcm	765	4	correlation	correlation	NN
cord-009417-458rrhcm	765	5	with	with	IN
cord-009417-458rrhcm	765	6	clinical	clinical	JJ
cord-009417-458rrhcm	765	7	bleeding	bleed	VBG
cord-009417-458rrhcm	765	8	Gamma	Gamma	NNP
cord-009417-458rrhcm	765	9	globulin	globulin	NN
cord-009417-458rrhcm	765	10	for	for	IN
cord-009417-458rrhcm	765	11	idiopathic	idiopathic	JJ
cord-009417-458rrhcm	765	12	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	765	13	purpura	purpura	NN
cord-009417-458rrhcm	765	14	Intravenous	Intravenous	NNP
cord-009417-458rrhcm	765	15	anti	anti	JJ
cord-009417-458rrhcm	765	16	-	-	JJ
cord-009417-458rrhcm	765	17	D	d	JJ
cord-009417-458rrhcm	765	18	treatment	treatment	NN
cord-009417-458rrhcm	765	19	of	of	IN
cord-009417-458rrhcm	765	20	immune	immune	JJ
cord-009417-458rrhcm	765	21	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	765	22	purpura	purpura	NN
cord-009417-458rrhcm	765	23	:	:	:
cord-009417-458rrhcm	765	24	Experience	experience	NN
cord-009417-458rrhcm	765	25	in	in	IN
cord-009417-458rrhcm	765	26	272	272	CD
cord-009417-458rrhcm	765	27	patients	patient	NNS
cord-009417-458rrhcm	765	28	Hazard	Hazard	NNP
cord-009417-458rrhcm	765	29	of	of	IN
cord-009417-458rrhcm	765	30	platelet	platelet	NN
cord-009417-458rrhcm	765	31	transfusion	transfusion	NN
cord-009417-458rrhcm	765	32	in	in	IN
cord-009417-458rrhcm	765	33	thrombotic	thrombotic	JJ
cord-009417-458rrhcm	765	34	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	765	35	purpura	purpura	NN
cord-009417-458rrhcm	765	36	Mantel	Mantel	NNP
cord-009417-458rrhcm	766	1	N	n	NN
cord-009417-458rrhcm	766	2	:	:	:
cord-009417-458rrhcm	767	1	The	the	DT
cord-009417-458rrhcm	767	2	quantitative	quantitative	JJ
cord-009417-458rrhcm	767	3	relation	relation	NN
cord-009417-458rrhcm	767	4	between	between	IN
cord-009417-458rrhcm	767	5	platelet	platelet	NN
cord-009417-458rrhcm	767	6	count	count	NN
cord-009417-458rrhcm	767	7	and	and	CC
cord-009417-458rrhcm	767	8	hemorrhage	hemorrhage	NN
cord-009417-458rrhcm	767	9	in	in	IN
cord-009417-458rrhcm	767	10	patients	patient	NNS
cord-009417-458rrhcm	767	11	with	with	IN
cord-009417-458rrhcm	767	12	acute	acute	JJ
cord-009417-458rrhcm	767	13	leukemia	leukemia	NN
cord-009417-458rrhcm	767	14	Controversies	controversy	NNS
cord-009417-458rrhcm	767	15	in	in	IN
cord-009417-458rrhcm	767	16	platelet	platelet	NN
cord-009417-458rrhcm	767	17	transfusion	transfusion	NN
cord-009417-458rrhcm	767	18	therapy	therapy	NN
cord-009417-458rrhcm	767	19	Safety	Safety	NNP
cord-009417-458rrhcm	767	20	of	of	IN
cord-009417-458rrhcm	767	21	stringent	stringent	JJ
cord-009417-458rrhcm	767	22	prophylactic	prophylactic	JJ
cord-009417-458rrhcm	767	23	platelet	platelet	NN
cord-009417-458rrhcm	767	24	transfusion	transfusion	NN
cord-009417-458rrhcm	767	25	policy	policy	NN
cord-009417-458rrhcm	767	26	for	for	IN
cord-009417-458rrhcm	767	27	patients	patient	NNS
cord-009417-458rrhcm	767	28	with	with	IN
cord-009417-458rrhcm	767	29	acute	acute	JJ
cord-009417-458rrhcm	767	30	leukemia	leukemia	NN
cord-009417-458rrhcm	768	1	The	the	DT
cord-009417-458rrhcm	768	2	natural	natural	JJ
cord-009417-458rrhcm	768	3	history	history	NN
cord-009417-458rrhcm	768	4	of	of	IN
cord-009417-458rrhcm	768	5	alloimmunization	alloimmunization	NN
cord-009417-458rrhcm	768	6	to	to	IN
cord-009417-458rrhcm	768	7	platelets	platelet	NNS
cord-009417-458rrhcm	768	8	Clinical	clinical	JJ
cord-009417-458rrhcm	768	9	factors	factor	NNS
cord-009417-458rrhcm	768	10	infl	infl	XX
cord-009417-458rrhcm	768	11	uencing	uence	VBG
cord-009417-458rrhcm	768	12	the	the	DT
cord-009417-458rrhcm	768	13	effi	effi	NNP
cord-009417-458rrhcm	768	14	cacy	cacy	NNP
cord-009417-458rrhcm	768	15	of	of	IN
cord-009417-458rrhcm	768	16	pooled	pool	VBN
cord-009417-458rrhcm	768	17	platelet	platelet	NN
cord-009417-458rrhcm	768	18	transfusions	transfusion	NNS
cord-009417-458rrhcm	768	19	Optimizing	optimize	VBG
cord-009417-458rrhcm	768	20	platelet	platelet	NN
cord-009417-458rrhcm	768	21	transfusion	transfusion	NN
cord-009417-458rrhcm	768	22	therapy	therapy	NN
cord-009417-458rrhcm	768	23	Current	current	JJ
cord-009417-458rrhcm	768	24	status	status	NN
cord-009417-458rrhcm	768	25	of	of	IN
cord-009417-458rrhcm	768	26	solvent	solvent	NN
cord-009417-458rrhcm	768	27	/	/	SYM
cord-009417-458rrhcm	768	28	detergenttreated	detergenttreate	VBN
cord-009417-458rrhcm	768	29	frozen	frozen	JJ
cord-009417-458rrhcm	768	30	plasma	plasma	NN
cord-009417-458rrhcm	768	31	Update	update	NN
cord-009417-458rrhcm	768	32	on	on	IN
cord-009417-458rrhcm	768	33	pathogen	pathogen	NN
cord-009417-458rrhcm	768	34	reduction	reduction	NN
cord-009417-458rrhcm	768	35	technology	technology	NN
cord-009417-458rrhcm	768	36	for	for	IN
cord-009417-458rrhcm	768	37	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	768	38	plasma	plasma	NN
cord-009417-458rrhcm	768	39	:	:	:
cord-009417-458rrhcm	769	1	An	an	DT
cord-009417-458rrhcm	769	2	overview	overview	NN
cord-009417-458rrhcm	769	3	National	National	NNP
cord-009417-458rrhcm	769	4	Institutes	Institutes	NNPS
cord-009417-458rrhcm	769	5	of	of	IN
cord-009417-458rrhcm	769	6	Health	Health	NNP
cord-009417-458rrhcm	769	7	Consensus	Consensus	NNP
cord-009417-458rrhcm	769	8	Conference	Conference	NNP
cord-009417-458rrhcm	769	9	:	:	:
cord-009417-458rrhcm	769	10	Fresh	fresh	JJ
cord-009417-458rrhcm	769	11	frozen	frozen	JJ
cord-009417-458rrhcm	769	12	plasma	plasma	NN
cord-009417-458rrhcm	769	13	:	:	:
cord-009417-458rrhcm	770	1	Indications	indication	NNS
cord-009417-458rrhcm	770	2	and	and	CC
cord-009417-458rrhcm	770	3	risks	risk	NNS
cord-009417-458rrhcm	770	4	The	the	DT
cord-009417-458rrhcm	770	5	role	role	NN
cord-009417-458rrhcm	770	6	of	of	IN
cord-009417-458rrhcm	770	7	prophylactic	prophylactic	JJ
cord-009417-458rrhcm	770	8	fresh	fresh	JJ
cord-009417-458rrhcm	770	9	frozen	frozen	JJ
cord-009417-458rrhcm	770	10	plasma	plasma	NN
cord-009417-458rrhcm	770	11	in	in	IN
cord-009417-458rrhcm	770	12	decreasing	decrease	VBG
cord-009417-458rrhcm	770	13	blood	blood	NN
cord-009417-458rrhcm	770	14	loss	loss	NN
cord-009417-458rrhcm	770	15	and	and	CC
cord-009417-458rrhcm	770	16	correcting	correct	VBG
cord-009417-458rrhcm	770	17	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	770	18	in	in	IN
cord-009417-458rrhcm	770	19	cardiac	cardiac	JJ
cord-009417-458rrhcm	770	20	surgery	surgery	NN
cord-009417-458rrhcm	770	21	:	:	:
cord-009417-458rrhcm	770	22	A	a	DT
cord-009417-458rrhcm	770	23	systematic	systematic	JJ
cord-009417-458rrhcm	770	24	review	review	NN
cord-009417-458rrhcm	771	1	Hemostasis	Hemostasis	NNP
cord-009417-458rrhcm	771	2	testing	testing	NN
cord-009417-458rrhcm	771	3	during	during	IN
cord-009417-458rrhcm	771	4	massive	massive	JJ
cord-009417-458rrhcm	771	5	blood	blood	NN
cord-009417-458rrhcm	771	6	replacement	replacement	NN
cord-009417-458rrhcm	771	7	:	:	:
cord-009417-458rrhcm	771	8	A	a	DT
cord-009417-458rrhcm	771	9	study	study	NN
cord-009417-458rrhcm	771	10	of	of	IN
cord-009417-458rrhcm	771	11	172	172	CD
cord-009417-458rrhcm	771	12	cases	case	NNS
cord-009417-458rrhcm	771	13	Should	Should	MD
cord-009417-458rrhcm	771	14	plasma	plasma	NN
cord-009417-458rrhcm	771	15	be	be	VB
cord-009417-458rrhcm	771	16	transfused	transfuse	VBN
cord-009417-458rrhcm	771	17	prophylactically	prophylactically	RB
cord-009417-458rrhcm	771	18	before	before	IN
cord-009417-458rrhcm	771	19	invasive	invasive	JJ
cord-009417-458rrhcm	771	20	procedures	procedure	NNS
cord-009417-458rrhcm	771	21	?	?	.
cord-009417-458rrhcm	772	1	Screening	screen	VBG
cord-009417-458rrhcm	772	2	for	for	IN
cord-009417-458rrhcm	772	3	the	the	DT
cord-009417-458rrhcm	772	4	risk	risk	NN
cord-009417-458rrhcm	772	5	for	for	IN
cord-009417-458rrhcm	772	6	bleeding	bleed	VBG
cord-009417-458rrhcm	772	7	or	or	CC
cord-009417-458rrhcm	772	8	thrombosis	thrombosis	NN
cord-009417-458rrhcm	772	9	Lack	lack	NN
cord-009417-458rrhcm	772	10	of	of	IN
cord-009417-458rrhcm	772	11	increased	increase	VBN
cord-009417-458rrhcm	772	12	bleeding	bleed	VBG
cord-009417-458rrhcm	772	13	after	after	IN
cord-009417-458rrhcm	772	14	liver	liver	NN
cord-009417-458rrhcm	772	15	biopsy	biopsy	NN
cord-009417-458rrhcm	772	16	in	in	IN
cord-009417-458rrhcm	772	17	patients	patient	NNS
cord-009417-458rrhcm	772	18	with	with	IN
cord-009417-458rrhcm	772	19	mild	mild	JJ
cord-009417-458rrhcm	772	20	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	772	21	abnormalities	abnormality	NNS
cord-009417-458rrhcm	773	1	Why	why	WRB
cord-009417-458rrhcm	773	2	is	be	VBZ
cord-009417-458rrhcm	773	3	fresh	fresh	RB
cord-009417-458rrhcm	773	4	-	-	HYPH
cord-009417-458rrhcm	773	5	frozen	frozen	JJ
cord-009417-458rrhcm	773	6	plasma	plasma	NN
cord-009417-458rrhcm	773	7	transfused	transfuse	VBN
cord-009417-458rrhcm	773	8	?	?	.
cord-009417-458rrhcm	774	1	Effect	effect	NN
cord-009417-458rrhcm	774	2	of	of	IN
cord-009417-458rrhcm	774	3	plasma	plasma	NN
cord-009417-458rrhcm	774	4	transfusions	transfusion	NNS
cord-009417-458rrhcm	774	5	on	on	IN
cord-009417-458rrhcm	774	6	the	the	DT
cord-009417-458rrhcm	774	7	prothrombin	prothrombin	NN
cord-009417-458rrhcm	774	8	time	time	NN
cord-009417-458rrhcm	774	9	and	and	CC
cord-009417-458rrhcm	774	10	clotting	clotting	NN
cord-009417-458rrhcm	774	11	factors	factor	NNS
cord-009417-458rrhcm	774	12	in	in	IN
cord-009417-458rrhcm	774	13	liver	liver	NN
cord-009417-458rrhcm	774	14	disease	disease	NN
cord-009417-458rrhcm	774	15	Clotting	clotting	NN
cord-009417-458rrhcm	774	16	factor	factor	NN
cord-009417-458rrhcm	774	17	levels	level	NNS
cord-009417-458rrhcm	774	18	and	and	CC
cord-009417-458rrhcm	774	19	the	the	DT
cord-009417-458rrhcm	774	20	risk	risk	NN
cord-009417-458rrhcm	774	21	of	of	IN
cord-009417-458rrhcm	774	22	diffuse	diffuse	JJ
cord-009417-458rrhcm	774	23	microvascular	microvascular	JJ
cord-009417-458rrhcm	774	24	bleeding	bleeding	NN
cord-009417-458rrhcm	774	25	in	in	IN
cord-009417-458rrhcm	774	26	the	the	DT
cord-009417-458rrhcm	774	27	massively	massively	RB
cord-009417-458rrhcm	774	28	transfused	transfused	JJ
cord-009417-458rrhcm	774	29	patient	patient	NN
cord-009417-458rrhcm	774	30	Fresh	Fresh	NNP
cord-009417-458rrhcm	774	31	frozen	frozen	JJ
cord-009417-458rrhcm	774	32	plasma	plasma	NN
cord-009417-458rrhcm	774	33	and	and	CC
cord-009417-458rrhcm	774	34	platelet	platelet	NN
cord-009417-458rrhcm	774	35	transfusion	transfusion	NN
cord-009417-458rrhcm	774	36	for	for	IN
cord-009417-458rrhcm	774	37	nonbleeding	nonbleede	VBG
cord-009417-458rrhcm	774	38	patients	patient	NNS
cord-009417-458rrhcm	774	39	in	in	IN
cord-009417-458rrhcm	774	40	the	the	DT
cord-009417-458rrhcm	774	41	intensive	intensive	JJ
cord-009417-458rrhcm	774	42	care	care	NN
cord-009417-458rrhcm	774	43	unit	unit	NN
cord-009417-458rrhcm	774	44	:	:	:
cord-009417-458rrhcm	774	45	Benefi	Benefi	NNP
cord-009417-458rrhcm	774	46	t	t	NN
cord-009417-458rrhcm	774	47	or	or	CC
cord-009417-458rrhcm	774	48	harm	harm	NN
cord-009417-458rrhcm	774	49	?	?	.
cord-009417-458rrhcm	775	1	Treatment	treatment	NN
cord-009417-458rrhcm	775	2	of	of	IN
cord-009417-458rrhcm	775	3	the	the	DT
cord-009417-458rrhcm	775	4	bleeding	bleeding	NN
cord-009417-458rrhcm	775	5	tendency	tendency	NN
cord-009417-458rrhcm	775	6	in	in	IN
cord-009417-458rrhcm	775	7	uremia	uremia	NN
cord-009417-458rrhcm	775	8	with	with	IN
cord-009417-458rrhcm	775	9	cryoprecipitate	cryoprecipitate	NNP
cord-009417-458rrhcm	775	10	Desmopressin	Desmopressin	NNP
cord-009417-458rrhcm	775	11	:	:	:
cord-009417-458rrhcm	776	1	A	a	DT
cord-009417-458rrhcm	776	2	nontransfusional	nontransfusional	JJ
cord-009417-458rrhcm	776	3	form	form	NN
cord-009417-458rrhcm	776	4	of	of	IN
cord-009417-458rrhcm	776	5	treatment	treatment	NN
cord-009417-458rrhcm	776	6	for	for	IN
cord-009417-458rrhcm	776	7	congenital	congenital	JJ
cord-009417-458rrhcm	776	8	and	and	CC
cord-009417-458rrhcm	776	9	acquired	acquire	VBN
cord-009417-458rrhcm	776	10	bleeding	bleeding	NN
cord-009417-458rrhcm	776	11	disorders	disorder	NNS
cord-009417-458rrhcm	777	1	Clinical	clinical	JJ
cord-009417-458rrhcm	777	2	uses	use	NNS
cord-009417-458rrhcm	777	3	of	of	IN
cord-009417-458rrhcm	777	4	intravenous	intravenous	JJ
cord-009417-458rrhcm	777	5	immunoglobulin	immunoglobulin	NN
cord-009417-458rrhcm	777	6	American	American	NNP
cord-009417-458rrhcm	777	7	College	College	NNP
cord-009417-458rrhcm	777	8	of	of	IN
cord-009417-458rrhcm	777	9	Obstetricians	Obstetricians	NNPS
cord-009417-458rrhcm	777	10	and	and	CC
cord-009417-458rrhcm	777	11	Gynecologists	Gynecologists	NNPS
cord-009417-458rrhcm	777	12	:	:	:
cord-009417-458rrhcm	777	13	Prevention	Prevention	NNP
cord-009417-458rrhcm	777	14	of	of	IN
cord-009417-458rrhcm	777	15	D	D	NNP
cord-009417-458rrhcm	777	16	Isoimmunization	Isoimmunization	NNP
cord-009417-458rrhcm	777	17	,	,	,
cord-009417-458rrhcm	777	18	Technical	Technical	NNP
cord-009417-458rrhcm	777	19	Bulletin	Bulletin	NNP
cord-009417-458rrhcm	778	1	No	no	DT
cord-009417-458rrhcm	778	2	147	147	CD
cord-009417-458rrhcm	778	3	Human	human	JJ
cord-009417-458rrhcm	778	4	albumin	albumin	NN
cord-009417-458rrhcm	778	5	solution	solution	NN
cord-009417-458rrhcm	778	6	for	for	IN
cord-009417-458rrhcm	778	7	resuscitation	resuscitation	NN
cord-009417-458rrhcm	778	8	and	and	CC
cord-009417-458rrhcm	778	9	volume	volume	NN
cord-009417-458rrhcm	778	10	expansion	expansion	NN
cord-009417-458rrhcm	778	11	in	in	IN
cord-009417-458rrhcm	778	12	critically	critically	RB
cord-009417-458rrhcm	778	13	ill	ill	JJ
cord-009417-458rrhcm	778	14	patients	patient	NNS
cord-009417-458rrhcm	779	1	Hypotension	hypotension	NN
cord-009417-458rrhcm	779	2	associated	associate	VBN
cord-009417-458rrhcm	779	3	with	with	IN
cord-009417-458rrhcm	779	4	prekallikrein	prekallikrein	NNP
cord-009417-458rrhcm	779	5	activator	activator	NN
cord-009417-458rrhcm	779	6	(	(	-LRB-
cord-009417-458rrhcm	779	7	Hageman	Hageman	NNP
cord-009417-458rrhcm	779	8	-	-	HYPH
cord-009417-458rrhcm	779	9	factor	factor	NN
cord-009417-458rrhcm	779	10	fragments	fragment	NNS
cord-009417-458rrhcm	779	11	)	)	-RRB-
cord-009417-458rrhcm	779	12	in	in	IN
cord-009417-458rrhcm	779	13	plasma	plasma	NN
cord-009417-458rrhcm	779	14	protein	protein	NN
cord-009417-458rrhcm	779	15	fraction	fraction	NN
cord-009417-458rrhcm	779	16	Granulocyte	Granulocyte	NNP
cord-009417-458rrhcm	779	17	transfusions	transfusion	NNS
cord-009417-458rrhcm	779	18	for	for	IN
cord-009417-458rrhcm	779	19	treating	treat	VBG
cord-009417-458rrhcm	779	20	infections	infection	NNS
cord-009417-458rrhcm	779	21	in	in	IN
cord-009417-458rrhcm	779	22	patients	patient	NNS
cord-009417-458rrhcm	779	23	with	with	IN
cord-009417-458rrhcm	779	24	neutropenia	neutropenia	NN
cord-009417-458rrhcm	779	25	or	or	CC
cord-009417-458rrhcm	779	26	neutrophil	neutrophil	NN
cord-009417-458rrhcm	779	27	dysfunction	dysfunction	NN
cord-009417-458rrhcm	780	1	Special	special	JJ
cord-009417-458rrhcm	780	2	report	report	NN
cord-009417-458rrhcm	780	3	:	:	:
cord-009417-458rrhcm	781	1	Transfusion	transfusion	NN
cord-009417-458rrhcm	781	2	risks	risk	VBZ
cord-009417-458rrhcm	781	3	Transfusion	transfusion	NN
cord-009417-458rrhcm	781	4	errors	error	NNS
cord-009417-458rrhcm	781	5	:	:	:
cord-009417-458rrhcm	782	1	Scope	scope	NN
cord-009417-458rrhcm	782	2	of	of	IN
cord-009417-458rrhcm	782	3	the	the	DT
cord-009417-458rrhcm	782	4	problem	problem	NN
cord-009417-458rrhcm	782	5	,	,	,
cord-009417-458rrhcm	782	6	consequences	consequence	NNS
cord-009417-458rrhcm	782	7	,	,	,
cord-009417-458rrhcm	782	8	and	and	CC
cord-009417-458rrhcm	782	9	solutions	solution	NNS
cord-009417-458rrhcm	782	10	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	782	11	errors	error	NNS
cord-009417-458rrhcm	782	12	in	in	IN
cord-009417-458rrhcm	782	13	New	New	NNP
cord-009417-458rrhcm	782	14	York	York	NNP
cord-009417-458rrhcm	782	15	State	State	NNP
cord-009417-458rrhcm	782	16	:	:	:
cord-009417-458rrhcm	782	17	An	an	DT
cord-009417-458rrhcm	782	18	analysis	analysis	NN
cord-009417-458rrhcm	782	19	of	of	IN
cord-009417-458rrhcm	782	20	10	10	CD
cord-009417-458rrhcm	782	21	years	year	NNS
cord-009417-458rrhcm	782	22	'	'	POS
cord-009417-458rrhcm	782	23	experience	experience	NN
cord-009417-458rrhcm	782	24	JCAHO	JCAHO	NNP
cord-009417-458rrhcm	782	25	:	:	:
cord-009417-458rrhcm	782	26	Blood	blood	NN
cord-009417-458rrhcm	782	27	transfusion	transfusion	NN
cord-009417-458rrhcm	782	28	errors	error	NNS
cord-009417-458rrhcm	783	1	:	:	:
cord-009417-458rrhcm	783	2	Preventing	prevent	VBG
cord-009417-458rrhcm	783	3	future	future	JJ
cord-009417-458rrhcm	783	4	occurrences	occurrence	NNS
cord-009417-458rrhcm	783	5	:	:	:
cord-009417-458rrhcm	783	6	Available	available	JJ
cord-009417-458rrhcm	783	7	at	at	IN
cord-009417-458rrhcm	783	8	Hemolytic	hemolytic	JJ
cord-009417-458rrhcm	783	9	transfusion	transfusion	NN
cord-009417-458rrhcm	783	10	reaction	reaction	NN
cord-009417-458rrhcm	783	11	Transfusion	transfusion	NN
cord-009417-458rrhcm	783	12	reactions	reaction	NNS
cord-009417-458rrhcm	783	13	associated	associate	VBN
cord-009417-458rrhcm	783	14	with	with	IN
cord-009417-458rrhcm	783	15	anti	anti	JJ
cord-009417-458rrhcm	783	16	-	-	JJ
cord-009417-458rrhcm	783	17	IgA	iga	JJ
cord-009417-458rrhcm	783	18	antibodies	antibody	NNS
cord-009417-458rrhcm	783	19	:	:	:
cord-009417-458rrhcm	783	20	Report	report	VB
cord-009417-458rrhcm	783	21	of	of	IN
cord-009417-458rrhcm	783	22	four	four	CD
cord-009417-458rrhcm	783	23	cases	case	NNS
cord-009417-458rrhcm	783	24	and	and	CC
cord-009417-458rrhcm	783	25	review	review	NN
cord-009417-458rrhcm	783	26	of	of	IN
cord-009417-458rrhcm	783	27	the	the	DT
cord-009417-458rrhcm	783	28	literature	literature	NN
cord-009417-458rrhcm	783	29	Febrile	febrile	JJ
cord-009417-458rrhcm	783	30	transfusion	transfusion	NN
cord-009417-458rrhcm	783	31	reaction	reaction	NN
cord-009417-458rrhcm	783	32	:	:	:
cord-009417-458rrhcm	783	33	What	what	WDT
cord-009417-458rrhcm	783	34	blood	blood	NN
cord-009417-458rrhcm	783	35	component	component	NN
cord-009417-458rrhcm	783	36	should	should	MD
cord-009417-458rrhcm	783	37	be	be	VB
cord-009417-458rrhcm	783	38	given	give	VBN
cord-009417-458rrhcm	783	39	next	next	RB
cord-009417-458rrhcm	783	40	?	?	.
cord-009417-458rrhcm	784	1	Clinical	clinical	JJ
cord-009417-458rrhcm	784	2	outcomes	outcome	NNS
cord-009417-458rrhcm	784	3	following	follow	VBG
cord-009417-458rrhcm	784	4	institution	institution	NN
cord-009417-458rrhcm	784	5	of	of	IN
cord-009417-458rrhcm	784	6	the	the	DT
cord-009417-458rrhcm	784	7	Canadian	canadian	JJ
cord-009417-458rrhcm	784	8	universal	universal	JJ
cord-009417-458rrhcm	784	9	leukoreduction	leukoreduction	NN
cord-009417-458rrhcm	784	10	program	program	NN
cord-009417-458rrhcm	784	11	for	for	IN
cord-009417-458rrhcm	784	12	red	red	JJ
cord-009417-458rrhcm	784	13	blood	blood	NN
cord-009417-458rrhcm	784	14	cell	cell	NN
cord-009417-458rrhcm	784	15	transfusions	transfusion	NNS
cord-009417-458rrhcm	785	1	Delayed	delayed	JJ
cord-009417-458rrhcm	785	2	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	785	3	transfusion	transfusion	NN
cord-009417-458rrhcm	785	4	reaction	reaction	NN
cord-009417-458rrhcm	785	5	:	:	:
cord-009417-458rrhcm	785	6	An	an	DT
cord-009417-458rrhcm	785	7	immunologic	immunologic	JJ
cord-009417-458rrhcm	785	8	hazard	hazard	NN
cord-009417-458rrhcm	785	9	of	of	IN
cord-009417-458rrhcm	785	10	blood	blood	NN
cord-009417-458rrhcm	785	11	transfusion	transfusion	NN
cord-009417-458rrhcm	785	12	Transfusion	transfusion	NN
cord-009417-458rrhcm	785	13	-	-	HYPH
cord-009417-458rrhcm	785	14	related	relate	VBN
cord-009417-458rrhcm	785	15	acute	acute	JJ
cord-009417-458rrhcm	785	16	lung	lung	NN
cord-009417-458rrhcm	785	17	injury	injury	NN
cord-009417-458rrhcm	785	18	and	and	CC
cord-009417-458rrhcm	785	19	pulmonary	pulmonary	JJ
cord-009417-458rrhcm	785	20	edema	edema	NN
cord-009417-458rrhcm	785	21	in	in	IN
cord-009417-458rrhcm	785	22	critically	critically	RB
cord-009417-458rrhcm	785	23	ill	ill	JJ
cord-009417-458rrhcm	785	24	patients	patient	NNS
cord-009417-458rrhcm	785	25	:	:	:
cord-009417-458rrhcm	785	26	A	a	DT
cord-009417-458rrhcm	785	27	retrospective	retrospective	JJ
cord-009417-458rrhcm	785	28	study	study	NN
cord-009417-458rrhcm	785	29	for	for	IN
cord-009417-458rrhcm	785	30	the	the	DT
cord-009417-458rrhcm	785	31	NHLBI	NHLBI	NNP
cord-009417-458rrhcm	785	32	Working	Working	NNP
cord-009417-458rrhcm	785	33	Group	Group	NNP
cord-009417-458rrhcm	785	34	on	on	IN
cord-009417-458rrhcm	785	35	TRALI	TRALI	NNP
cord-009417-458rrhcm	785	36	:	:	:
cord-009417-458rrhcm	785	37	Transfusion	transfusion	NN
cord-009417-458rrhcm	785	38	-	-	HYPH
cord-009417-458rrhcm	785	39	related	relate	VBN
cord-009417-458rrhcm	785	40	acute	acute	JJ
cord-009417-458rrhcm	785	41	lung	lung	NN
cord-009417-458rrhcm	785	42	injury	injury	NN
cord-009417-458rrhcm	785	43	:	:	:
cord-009417-458rrhcm	786	1	Defi	Defi	NNP
cord-009417-458rrhcm	786	2	nition	nition	NN
cord-009417-458rrhcm	786	3	and	and	CC
cord-009417-458rrhcm	786	4	review	review	VB
cord-009417-458rrhcm	786	5	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	786	6	-	-	HYPH
cord-009417-458rrhcm	786	7	associated	associate	VBN
cord-009417-458rrhcm	786	8	acute	acute	JJ
cord-009417-458rrhcm	786	9	lung	lung	NN
cord-009417-458rrhcm	786	10	injury	injury	NN
cord-009417-458rrhcm	786	11	(	(	-LRB-
cord-009417-458rrhcm	786	12	TRALI	TRALI	NNP
cord-009417-458rrhcm	786	13	)	)	-RRB-
cord-009417-458rrhcm	786	14	:	:	:
cord-009417-458rrhcm	786	15	Clinical	clinical	JJ
cord-009417-458rrhcm	786	16	presentation	presentation	NN
cord-009417-458rrhcm	786	17	,	,	,
cord-009417-458rrhcm	786	18	treatment	treatment	NN
cord-009417-458rrhcm	786	19	and	and	CC
cord-009417-458rrhcm	786	20	prognosis	prognosis	NN
cord-009417-458rrhcm	786	21	Transfusion	transfusion	NN
cord-009417-458rrhcm	786	22	-	-	HYPH
cord-009417-458rrhcm	786	23	related	relate	VBN
cord-009417-458rrhcm	786	24	acute	acute	JJ
cord-009417-458rrhcm	786	25	lung	lung	NN
cord-009417-458rrhcm	786	26	injury	injury	NN
cord-009417-458rrhcm	786	27	caused	cause	VBN
cord-009417-458rrhcm	786	28	by	by	IN
cord-009417-458rrhcm	786	29	two	two	CD
cord-009417-458rrhcm	786	30	donors	donor	NNS
cord-009417-458rrhcm	786	31	with	with	IN
cord-009417-458rrhcm	786	32	antihuman	antihuman	JJ
cord-009417-458rrhcm	786	33	leucocyte	leucocyte	NNP
cord-009417-458rrhcm	786	34	antigen	antigen	NNP
cord-009417-458rrhcm	786	35	class	class	NN
cord-009417-458rrhcm	786	36	II	II	NNP
cord-009417-458rrhcm	786	37	antibodies	antibody	NNS
cord-009417-458rrhcm	786	38	:	:	:
cord-009417-458rrhcm	786	39	A	a	DT
cord-009417-458rrhcm	786	40	look	look	VB
cord-009417-458rrhcm	786	41	-	-	HYPH
cord-009417-458rrhcm	786	42	back	back	RP
cord-009417-458rrhcm	786	43	investigation	investigation	NN
cord-009417-458rrhcm	786	44	for	for	IN
cord-009417-458rrhcm	786	45	the	the	DT
cord-009417-458rrhcm	786	46	TRALI	TRALI	NNP
cord-009417-458rrhcm	786	47	Consensus	Consensus	NNP
cord-009417-458rrhcm	786	48	Panel	Panel	NNP
cord-009417-458rrhcm	786	49	:	:	:
cord-009417-458rrhcm	786	50	Proceedings	proceeding	NNS
cord-009417-458rrhcm	786	51	of	of	IN
cord-009417-458rrhcm	786	52	a	a	DT
cord-009417-458rrhcm	786	53	consensus	consensus	NN
cord-009417-458rrhcm	786	54	conference	conference	NN
cord-009417-458rrhcm	786	55	:	:	:
cord-009417-458rrhcm	787	1	Towards	towards	IN
cord-009417-458rrhcm	787	2	an	an	DT
cord-009417-458rrhcm	787	3	understanding	understanding	NN
cord-009417-458rrhcm	787	4	of	of	IN
cord-009417-458rrhcm	787	5	TRALI	TRALI	NNP
cord-009417-458rrhcm	787	6	Graft	graft	NN
cord-009417-458rrhcm	787	7	-	-	HYPH
cord-009417-458rrhcm	787	8	versushost	versushost	NN
cord-009417-458rrhcm	787	9	disease	disease	NN
cord-009417-458rrhcm	787	10	:	:	:
cord-009417-458rrhcm	787	11	New	new	JJ
cord-009417-458rrhcm	787	12	directions	direction	NNS
cord-009417-458rrhcm	787	13	for	for	IN
cord-009417-458rrhcm	787	14	a	a	DT
cord-009417-458rrhcm	787	15	persistent	persistent	JJ
cord-009417-458rrhcm	787	16	problem	problem	NN
cord-009417-458rrhcm	787	17	Survey	Survey	NNP
cord-009417-458rrhcm	787	18	of	of	IN
cord-009417-458rrhcm	787	19	transfusion	transfusion	NN
cord-009417-458rrhcm	787	20	-	-	HYPH
cord-009417-458rrhcm	787	21	associated	associate	VBN
cord-009417-458rrhcm	787	22	graft	graft	NN
cord-009417-458rrhcm	787	23	-	-	HYPH
cord-009417-458rrhcm	787	24	versus	versus	IN
cord-009417-458rrhcm	787	25	-	-	HYPH
cord-009417-458rrhcm	787	26	host	host	NN
cord-009417-458rrhcm	787	27	disease	disease	NN
cord-009417-458rrhcm	787	28	in	in	IN
cord-009417-458rrhcm	787	29	immunocompetent	immunocompetent	JJ
cord-009417-458rrhcm	787	30	recipients	recipient	NNS
cord-009417-458rrhcm	788	1	The	the	DT
cord-009417-458rrhcm	788	2	effect	effect	NN
cord-009417-458rrhcm	788	3	of	of	IN
cord-009417-458rrhcm	788	4	prestorage	prestorage	NN
cord-009417-458rrhcm	788	5	irradiation	irradiation	NN
cord-009417-458rrhcm	788	6	on	on	IN
cord-009417-458rrhcm	788	7	post	post	JJ
cord-009417-458rrhcm	788	8	-	-	JJ
cord-009417-458rrhcm	788	9	transfusion	transfusion	JJ
cord-009417-458rrhcm	788	10	red	red	JJ
cord-009417-458rrhcm	788	11	cell	cell	NN
cord-009417-458rrhcm	788	12	survival	survival	NN
cord-009417-458rrhcm	788	13	Improvement	improvement	NN
cord-009417-458rrhcm	788	14	of	of	IN
cord-009417-458rrhcm	788	15	kidney	kidney	NN
cord-009417-458rrhcm	788	16	-	-	HYPH
cord-009417-458rrhcm	788	17	graft	graft	NN
cord-009417-458rrhcm	788	18	survival	survival	NN
cord-009417-458rrhcm	788	19	with	with	IN
cord-009417-458rrhcm	788	20	increased	increase	VBN
cord-009417-458rrhcm	788	21	numbers	number	NNS
cord-009417-458rrhcm	788	22	of	of	IN
cord-009417-458rrhcm	788	23	blood	blood	NN
cord-009417-458rrhcm	788	24	transfusion	transfusion	NN
cord-009417-458rrhcm	788	25	Blood	blood	NN
cord-009417-458rrhcm	788	26	transfusion	transfusion	NN
cord-009417-458rrhcm	788	27	-	-	HYPH
cord-009417-458rrhcm	788	28	modulated	modulate	VBN
cord-009417-458rrhcm	788	29	tumor	tumor	NN
cord-009417-458rrhcm	788	30	recurrence	recurrence	NN
cord-009417-458rrhcm	788	31	:	:	:
cord-009417-458rrhcm	788	32	First	first	JJ
cord-009417-458rrhcm	788	33	results	result	NNS
cord-009417-458rrhcm	788	34	of	of	IN
cord-009417-458rrhcm	788	35	a	a	DT
cord-009417-458rrhcm	788	36	randomized	randomized	JJ
cord-009417-458rrhcm	788	37	study	study	NN
cord-009417-458rrhcm	788	38	of	of	IN
cord-009417-458rrhcm	788	39	autologous	autologous	JJ
cord-009417-458rrhcm	788	40	versus	versus	IN
cord-009417-458rrhcm	788	41	allogeneic	allogeneic	IN
cord-009417-458rrhcm	788	42	blood	blood	NN
cord-009417-458rrhcm	788	43	transfusion	transfusion	NN
cord-009417-458rrhcm	788	44	in	in	IN
cord-009417-458rrhcm	788	45	colorectal	colorectal	JJ
cord-009417-458rrhcm	788	46	cancer	cancer	NN
cord-009417-458rrhcm	788	47	surgery	surgery	NN
cord-009417-458rrhcm	788	48	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	788	49	-	-	HYPH
cord-009417-458rrhcm	788	50	associated	associate	VBN
cord-009417-458rrhcm	788	51	cancer	cancer	NN
cord-009417-458rrhcm	788	52	recurrence	recurrence	NN
cord-009417-458rrhcm	788	53	and	and	CC
cord-009417-458rrhcm	788	54	postoperative	postoperative	JJ
cord-009417-458rrhcm	788	55	infection	infection	NN
cord-009417-458rrhcm	788	56	:	:	:
cord-009417-458rrhcm	788	57	Meta	Meta	NNP
cord-009417-458rrhcm	788	58	-	-	HYPH
cord-009417-458rrhcm	788	59	analysis	analysis	NN
cord-009417-458rrhcm	788	60	of	of	IN
cord-009417-458rrhcm	788	61	randomized	randomized	JJ
cord-009417-458rrhcm	788	62	,	,	,
cord-009417-458rrhcm	788	63	controlled	control	VBN
cord-009417-458rrhcm	788	64	clinical	clinical	JJ
cord-009417-458rrhcm	788	65	trials	trial	NNS
cord-009417-458rrhcm	788	66	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	788	67	practice	practice	NN
cord-009417-458rrhcm	788	68	and	and	CC
cord-009417-458rrhcm	788	69	nosocomial	nosocomial	JJ
cord-009417-458rrhcm	788	70	infection	infection	NN
cord-009417-458rrhcm	788	71	:	:	:
cord-009417-458rrhcm	788	72	Assessing	assess	VBG
cord-009417-458rrhcm	788	73	the	the	DT
cord-009417-458rrhcm	788	74	evidence	evidence	NN
cord-009417-458rrhcm	788	75	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	788	76	increases	increase	VBZ
cord-009417-458rrhcm	788	77	the	the	DT
cord-009417-458rrhcm	788	78	risk	risk	NN
cord-009417-458rrhcm	788	79	of	of	IN
cord-009417-458rrhcm	788	80	postoperative	postoperative	JJ
cord-009417-458rrhcm	788	81	infection	infection	NN
cord-009417-458rrhcm	788	82	after	after	IN
cord-009417-458rrhcm	788	83	cardiovascular	cardiovascular	JJ
cord-009417-458rrhcm	788	84	surgery	surgery	NN
cord-009417-458rrhcm	788	85	Immunosuppressive	immunosuppressive	JJ
cord-009417-458rrhcm	788	86	effects	effect	NNS
cord-009417-458rrhcm	788	87	of	of	IN
cord-009417-458rrhcm	788	88	blood	blood	NN
cord-009417-458rrhcm	788	89	transfusion	transfusion	NN
cord-009417-458rrhcm	788	90	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	788	91	of	of	IN
cord-009417-458rrhcm	788	92	leukoreduced	leukoreduce	VBN
cord-009417-458rrhcm	788	93	red	red	JJ
cord-009417-458rrhcm	788	94	blood	blood	NN
cord-009417-458rrhcm	788	95	cells	cell	NNS
cord-009417-458rrhcm	788	96	may	may	MD
cord-009417-458rrhcm	788	97	decrease	decrease	VB
cord-009417-458rrhcm	788	98	postoperative	postoperative	JJ
cord-009417-458rrhcm	788	99	infections	infection	NNS
cord-009417-458rrhcm	788	100	:	:	:
cord-009417-458rrhcm	789	1	Two	two	CD
cord-009417-458rrhcm	789	2	meta	meta	JJ
cord-009417-458rrhcm	789	3	-	-	HYPH
cord-009417-458rrhcm	789	4	analyses	analysis	NNS
cord-009417-458rrhcm	789	5	of	of	IN
cord-009417-458rrhcm	789	6	randomized	randomized	JJ
cord-009417-458rrhcm	789	7	controlled	control	VBN
cord-009417-458rrhcm	789	8	trials	trial	NNS
cord-009417-458rrhcm	789	9	Transfusion	Transfusion	NNP
cord-009417-458rrhcm	789	10	immunomodulation	immunomodulation	NN
cord-009417-458rrhcm	789	11	or	or	CC
cord-009417-458rrhcm	789	12	TRIM	trim	NN
cord-009417-458rrhcm	789	13	:	:	:
cord-009417-458rrhcm	790	1	What	what	WP
cord-009417-458rrhcm	790	2	does	do	VBZ
cord-009417-458rrhcm	790	3	it	-PRON-	PRP
cord-009417-458rrhcm	790	4	mean	mean	VB
cord-009417-458rrhcm	790	5	clinically	clinically	RB
cord-009417-458rrhcm	790	6	?	?	.
cord-009417-458rrhcm	791	1	Risks	risk	NNS
cord-009417-458rrhcm	791	2	of	of	IN
cord-009417-458rrhcm	791	3	blood	blood	NN
cord-009417-458rrhcm	791	4	transfusion	transfusion	NN
cord-009417-458rrhcm	791	5	Transfusiontransmitted	transfusiontransmitte	VBD
cord-009417-458rrhcm	791	6	cytomegalovirus	cytomegalovirus	NNP
cord-009417-458rrhcm	791	7	and	and	CC
cord-009417-458rrhcm	791	8	Epstein	Epstein	NNP
cord-009417-458rrhcm	791	9	-	-	HYPH
cord-009417-458rrhcm	791	10	Barr	Barr	NNP
cord-009417-458rrhcm	791	11	virus	virus	NN
cord-009417-458rrhcm	791	12	diseases	disease	VBZ
cord-009417-458rrhcm	791	13	Current	current	JJ
cord-009417-458rrhcm	791	14	status	status	NN
cord-009417-458rrhcm	791	15	of	of	IN
cord-009417-458rrhcm	791	16	microbial	microbial	JJ
cord-009417-458rrhcm	791	17	contamination	contamination	NN
cord-009417-458rrhcm	791	18	of	of	IN
cord-009417-458rrhcm	791	19	blood	blood	NN
cord-009417-458rrhcm	791	20	components	component	NNS
cord-009417-458rrhcm	791	21	:	:	:
cord-009417-458rrhcm	791	22	Summary	summary	NN
cord-009417-458rrhcm	791	23	of	of	IN
cord-009417-458rrhcm	791	24	a	a	DT
cord-009417-458rrhcm	791	25	conference	conference	NN
cord-009417-458rrhcm	791	26	Septic	septic	JJ
cord-009417-458rrhcm	791	27	reactions	reaction	NNS
cord-009417-458rrhcm	791	28	to	to	IN
cord-009417-458rrhcm	791	29	platelet	platelet	NN
cord-009417-458rrhcm	791	30	transfusions	transfusion	NNS
cord-009417-458rrhcm	791	31	:	:	:
cord-009417-458rrhcm	792	1	A	a	DT
cord-009417-458rrhcm	792	2	persistent	persistent	JJ
cord-009417-458rrhcm	792	3	problem	problem	NN
cord-009417-458rrhcm	792	4	Red	red	JJ
cord-009417-458rrhcm	792	5	blood	blood	NN
cord-009417-458rrhcm	792	6	cell	cell	NN
cord-009417-458rrhcm	792	7	transfusions	transfusion	NNS
cord-009417-458rrhcm	792	8	contaminated	contaminate	VBN
cord-009417-458rrhcm	792	9	with	with	IN
cord-009417-458rrhcm	792	10	Yersinia	Yersinia	NNP
cord-009417-458rrhcm	792	11	enterocolitica	enterocolitica	NNP
cord-009417-458rrhcm	792	12	-	-	HYPH
cord-009417-458rrhcm	792	13	United	United	NNP
cord-009417-458rrhcm	792	14	States	States	NNP
cord-009417-458rrhcm	792	15	,	,	,
cord-009417-458rrhcm	792	16	1991	1991	CD
cord-009417-458rrhcm	792	17	-	-	SYM
cord-009417-458rrhcm	792	18	1997	1997	CD
cord-009417-458rrhcm	792	19	,	,	,
cord-009417-458rrhcm	792	20	and	and	CC
cord-009417-458rrhcm	792	21	initiation	initiation	NN
cord-009417-458rrhcm	792	22	of	of	IN
cord-009417-458rrhcm	792	23	a	a	DT
cord-009417-458rrhcm	792	24	national	national	JJ
cord-009417-458rrhcm	792	25	study	study	NN
cord-009417-458rrhcm	792	26	to	to	TO
cord-009417-458rrhcm	792	27	detect	detect	VB
cord-009417-458rrhcm	792	28	bacteria	bacteria	NNS
cord-009417-458rrhcm	792	29	-	-	HYPH
cord-009417-458rrhcm	792	30	associated	associate	VBN
cord-009417-458rrhcm	792	31	transfusion	transfusion	NN
cord-009417-458rrhcm	792	32	reactions	reaction	NNS
cord-009417-458rrhcm	792	33	Routes	route	NNS
cord-009417-458rrhcm	792	34	of	of	IN
cord-009417-458rrhcm	792	35	infection	infection	NN
cord-009417-458rrhcm	792	36	,	,	,
cord-009417-458rrhcm	792	37	viremia	viremia	NN
cord-009417-458rrhcm	792	38	,	,	,
cord-009417-458rrhcm	792	39	and	and	CC
cord-009417-458rrhcm	792	40	liver	liver	NN
cord-009417-458rrhcm	792	41	disease	disease	NN
cord-009417-458rrhcm	792	42	in	in	IN
cord-009417-458rrhcm	792	43	blood	blood	NN
cord-009417-458rrhcm	792	44	donors	donor	NNS
cord-009417-458rrhcm	792	45	found	find	VBN
cord-009417-458rrhcm	792	46	to	to	TO
cord-009417-458rrhcm	792	47	have	have	VB
cord-009417-458rrhcm	792	48	hepatitis	hepatitis	NN
cord-009417-458rrhcm	792	49	C	C	NNP
cord-009417-458rrhcm	792	50	infection	infection	NN
cord-009417-458rrhcm	792	51	Clinical	clinical	JJ
cord-009417-458rrhcm	792	52	outcomes	outcome	NNS
cord-009417-458rrhcm	792	53	after	after	IN
cord-009417-458rrhcm	792	54	transfusionassociated	transfusionassociate	VBN
cord-009417-458rrhcm	792	55	hepatitis	hepatitis	NN
cord-009417-458rrhcm	792	56	C	C	NNP
cord-009417-458rrhcm	792	57	Adverse	adverse	JJ
cord-009417-458rrhcm	792	58	consequences	consequence	NNS
cord-009417-458rrhcm	792	59	of	of	IN
cord-009417-458rrhcm	792	60	blood	blood	NN
cord-009417-458rrhcm	792	61	transfusion	transfusion	NN
cord-009417-458rrhcm	793	1	:	:	:
cord-009417-458rrhcm	793	2	Quantitative	quantitative	JJ
cord-009417-458rrhcm	793	3	risk	risk	NN
cord-009417-458rrhcm	793	4	estimates	estimate	VBZ
cord-009417-458rrhcm	793	5	Stramer	Stramer	NNP
cord-009417-458rrhcm	793	6	SL	SL	NNP
cord-009417-458rrhcm	793	7	:	:	:
cord-009417-458rrhcm	793	8	Current	current	JJ
cord-009417-458rrhcm	793	9	prevalence	prevalence	NN
cord-009417-458rrhcm	793	10	and	and	CC
cord-009417-458rrhcm	793	11	incidence	incidence	NN
cord-009417-458rrhcm	793	12	of	of	IN
cord-009417-458rrhcm	793	13	infectious	infectious	JJ
cord-009417-458rrhcm	793	14	disease	disease	NN
cord-009417-458rrhcm	793	15	markers	marker	NNS
cord-009417-458rrhcm	793	16	and	and	CC
cord-009417-458rrhcm	793	17	estimated	estimate	VBN
cord-009417-458rrhcm	793	18	window	window	NN
cord-009417-458rrhcm	793	19	-	-	HYPH
cord-009417-458rrhcm	793	20	period	period	NN
cord-009417-458rrhcm	793	21	risk	risk	NN
cord-009417-458rrhcm	793	22	in	in	IN
cord-009417-458rrhcm	793	23	the	the	DT
cord-009417-458rrhcm	793	24	American	American	NNP
cord-009417-458rrhcm	793	25	Red	Red	NNP
cord-009417-458rrhcm	793	26	Cross	Cross	NNP
cord-009417-458rrhcm	793	27	blood	blood	NN
cord-009417-458rrhcm	793	28	donor	donor	NN
cord-009417-458rrhcm	793	29	population	population	NN
cord-009417-458rrhcm	794	1	Possible	possible	JJ
cord-009417-458rrhcm	794	2	transfusionassociated	transfusionassociated	NNP
cord-009417-458rrhcm	794	3	acquired	acquire	VBD
cord-009417-458rrhcm	794	4	immune	immune	NNP
cord-009417-458rrhcm	794	5	defi	defi	NNP
cord-009417-458rrhcm	794	6	ciency	ciency	NNP
cord-009417-458rrhcm	794	7	syndrome	syndrome	NN
cord-009417-458rrhcm	794	8	(	(	-LRB-
cord-009417-458rrhcm	794	9	AIDS	AIDS	NNP
cord-009417-458rrhcm	794	10	)	)	-RRB-
cord-009417-458rrhcm	795	1	:	:	:
cord-009417-458rrhcm	795	2	California	California	NNP
cord-009417-458rrhcm	795	3	Impact	Impact	NNP
cord-009417-458rrhcm	795	4	of	of	IN
cord-009417-458rrhcm	795	5	explicit	explicit	JJ
cord-009417-458rrhcm	795	6	questions	question	NNS
cord-009417-458rrhcm	795	7	about	about	IN
cord-009417-458rrhcm	795	8	high	high	JJ
cord-009417-458rrhcm	795	9	-	-	HYPH
cord-009417-458rrhcm	795	10	risk	risk	NN
cord-009417-458rrhcm	795	11	activities	activity	NNS
cord-009417-458rrhcm	795	12	on	on	IN
cord-009417-458rrhcm	795	13	donor	donor	NN
cord-009417-458rrhcm	795	14	attitudes	attitude	NNS
cord-009417-458rrhcm	795	15	and	and	CC
cord-009417-458rrhcm	795	16	donor	donor	NN
cord-009417-458rrhcm	795	17	referral	referral	NN
cord-009417-458rrhcm	795	18	patterns	pattern	NNS
cord-009417-458rrhcm	795	19	.	.	.
cord-009417-458rrhcm	796	1	Results	result	NNS
cord-009417-458rrhcm	796	2	in	in	IN
cord-009417-458rrhcm	796	3	two	two	CD
cord-009417-458rrhcm	796	4	community	community	NN
cord-009417-458rrhcm	796	5	blood	blood	NN
cord-009417-458rrhcm	796	6	centers	center	NNS
cord-009417-458rrhcm	797	1	The	the	DT
cord-009417-458rrhcm	797	2	effectiveness	effectiveness	NN
cord-009417-458rrhcm	797	3	of	of	IN
cord-009417-458rrhcm	797	4	the	the	DT
cord-009417-458rrhcm	797	5	confi	confi	NNP
cord-009417-458rrhcm	797	6	dential	dential	NNP
cord-009417-458rrhcm	797	7	unit	unit	NN
cord-009417-458rrhcm	797	8	exclusion	exclusion	NN
cord-009417-458rrhcm	797	9	option	option	NN
cord-009417-458rrhcm	797	10	Human	Human	NNP
cord-009417-458rrhcm	797	11	immunodefi	immunodefi	NNP
cord-009417-458rrhcm	797	12	ciency	ciency	NNP
cord-009417-458rrhcm	797	13	virus	virus	NN
cord-009417-458rrhcm	797	14	type	type	NN
cord-009417-458rrhcm	797	15	2	2	CD
cord-009417-458rrhcm	797	16	infection	infection	NN
cord-009417-458rrhcm	797	17	in	in	IN
cord-009417-458rrhcm	797	18	the	the	DT
cord-009417-458rrhcm	797	19	United	United	NNP
cord-009417-458rrhcm	797	20	States	States	NNP
cord-009417-458rrhcm	797	21	:	:	:
cord-009417-458rrhcm	797	22	Epidemiology	epidemiology	NN
cord-009417-458rrhcm	797	23	,	,	,
cord-009417-458rrhcm	797	24	diagnosis	diagnosis	NN
cord-009417-458rrhcm	797	25	,	,	,
cord-009417-458rrhcm	797	26	and	and	CC
cord-009417-458rrhcm	797	27	public	public	JJ
cord-009417-458rrhcm	797	28	health	health	NN
cord-009417-458rrhcm	797	29	implications	implication	NNS
cord-009417-458rrhcm	798	1	Update	update	NN
cord-009417-458rrhcm	798	2	:	:	:
cord-009417-458rrhcm	799	1	HIV-2	hiv-2	VB
cord-009417-458rrhcm	799	2	infection	infection	NN
cord-009417-458rrhcm	799	3	among	among	IN
cord-009417-458rrhcm	799	4	blood	blood	NN
cord-009417-458rrhcm	799	5	and	and	CC
cord-009417-458rrhcm	799	6	plasma	plasma	NN
cord-009417-458rrhcm	799	7	donors	donor	NNS
cord-009417-458rrhcm	799	8	-	-	:
cord-009417-458rrhcm	799	9	United	United	NNP
cord-009417-458rrhcm	799	10	States	States	NNP
cord-009417-458rrhcm	799	11	Transmission	Transmission	NNP
cord-009417-458rrhcm	799	12	of	of	IN
cord-009417-458rrhcm	799	13	human	human	JJ
cord-009417-458rrhcm	799	14	Tlymphotropic	Tlymphotropic	NNP
cord-009417-458rrhcm	799	15	virus	virus	NN
cord-009417-458rrhcm	799	16	types	type	NNS
cord-009417-458rrhcm	799	17	I	-PRON-	PRP
cord-009417-458rrhcm	799	18	and	and	CC
cord-009417-458rrhcm	799	19	II	II	NNP
cord-009417-458rrhcm	799	20	by	by	IN
cord-009417-458rrhcm	799	21	blood	blood	NN
cord-009417-458rrhcm	799	22	transfusion	transfusion	NN
cord-009417-458rrhcm	800	1	A	a	DT
cord-009417-458rrhcm	800	2	prospective	prospective	JJ
cord-009417-458rrhcm	800	3	study	study	NN
cord-009417-458rrhcm	800	4	of	of	IN
cord-009417-458rrhcm	800	5	transmission	transmission	NN
cord-009417-458rrhcm	800	6	by	by	IN
cord-009417-458rrhcm	800	7	transfusion	transfusion	NN
cord-009417-458rrhcm	800	8	of	of	IN
cord-009417-458rrhcm	800	9	HTLV	HTLV	NNP
cord-009417-458rrhcm	800	10	-	-	HYPH
cord-009417-458rrhcm	800	11	I	i	NN
cord-009417-458rrhcm	800	12	and	and	CC
cord-009417-458rrhcm	800	13	risk	risk	NN
cord-009417-458rrhcm	800	14	factors	factor	NNS
cord-009417-458rrhcm	800	15	associated	associate	VBN
cord-009417-458rrhcm	800	16	with	with	IN
cord-009417-458rrhcm	800	17	seroconversion	seroconversion	NN
cord-009417-458rrhcm	800	18	Post	post	JJ
cord-009417-458rrhcm	800	19	-	-	JJ
cord-009417-458rrhcm	800	20	transfusion	transfusion	NN
cord-009417-458rrhcm	800	21	cytomegalovirus	cytomegalovirus	NN
cord-009417-458rrhcm	800	22	infections	infection	NNS
cord-009417-458rrhcm	800	23	Reducing	reduce	VBG
cord-009417-458rrhcm	800	24	the	the	DT
cord-009417-458rrhcm	800	25	risk	risk	NN
cord-009417-458rrhcm	800	26	for	for	IN
cord-009417-458rrhcm	800	27	transfusion	transfusion	NN
cord-009417-458rrhcm	800	28	-	-	HYPH
cord-009417-458rrhcm	800	29	transmitted	transmit	VBN
cord-009417-458rrhcm	800	30	cytomegalovirus	cytomegalovirus	JJ
cord-009417-458rrhcm	800	31	infection	infection	NN
cord-009417-458rrhcm	800	32	Is	be	VBZ
cord-009417-458rrhcm	800	33	white	white	JJ
cord-009417-458rrhcm	800	34	blood	blood	NN
cord-009417-458rrhcm	800	35	cell	cell	NN
cord-009417-458rrhcm	800	36	reduction	reduction	NN
cord-009417-458rrhcm	800	37	equivalent	equivalent	JJ
cord-009417-458rrhcm	800	38	to	to	IN
cord-009417-458rrhcm	800	39	antibody	antibody	NN
cord-009417-458rrhcm	800	40	screening	screening	NN
cord-009417-458rrhcm	800	41	in	in	IN
cord-009417-458rrhcm	800	42	preventing	prevent	VBG
cord-009417-458rrhcm	800	43	transmission	transmission	NN
cord-009417-458rrhcm	800	44	of	of	IN
cord-009417-458rrhcm	800	45	cytomegalovirus	cytomegalovirus	NN
cord-009417-458rrhcm	800	46	by	by	IN
cord-009417-458rrhcm	800	47	transfusion	transfusion	NN
cord-009417-458rrhcm	800	48	?	?	.
cord-009417-458rrhcm	801	1	A	a	DT
cord-009417-458rrhcm	801	2	review	review	NN
cord-009417-458rrhcm	801	3	of	of	IN
cord-009417-458rrhcm	801	4	the	the	DT
cord-009417-458rrhcm	801	5	literature	literature	NN
cord-009417-458rrhcm	801	6	and	and	CC
cord-009417-458rrhcm	801	7	meta	meta	NNP
cord-009417-458rrhcm	801	8	-	-	HYPH
cord-009417-458rrhcm	801	9	analysis	analysis	NN
cord-009417-458rrhcm	801	10	Transmission	transmission	NN
cord-009417-458rrhcm	801	11	of	of	IN
cord-009417-458rrhcm	801	12	parasitic	parasitic	JJ
cord-009417-458rrhcm	801	13	infections	infection	NNS
cord-009417-458rrhcm	801	14	by	by	IN
cord-009417-458rrhcm	801	15	blood	blood	NN
cord-009417-458rrhcm	801	16	transfusion	transfusion	NN
cord-009417-458rrhcm	801	17	Hemostasis	Hemostasis	NNP
cord-009417-458rrhcm	801	18	in	in	IN
cord-009417-458rrhcm	801	19	massively	massively	RB
cord-009417-458rrhcm	801	20	transfused	transfuse	VBN
cord-009417-458rrhcm	801	21	trauma	trauma	NN
cord-009417-458rrhcm	801	22	patients	patient	NNS
cord-009417-458rrhcm	802	1	Laboratory	laboratory	NN
cord-009417-458rrhcm	802	2	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	802	3	abnormalities	abnormality	NNS
cord-009417-458rrhcm	802	4	in	in	IN
cord-009417-458rrhcm	802	5	massively	massively	RB
cord-009417-458rrhcm	802	6	transfused	transfuse	VBN
cord-009417-458rrhcm	802	7	patients	patient	NNS
cord-009417-458rrhcm	802	8	given	give	VBN
cord-009417-458rrhcm	802	9	red	red	JJ
cord-009417-458rrhcm	802	10	blood	blood	NN
cord-009417-458rrhcm	802	11	cells	cell	NNS
cord-009417-458rrhcm	802	12	and	and	CC
cord-009417-458rrhcm	802	13	crystalloid	crystalloid	NN
cord-009417-458rrhcm	802	14	Serial	serial	JJ
cord-009417-458rrhcm	802	15	changes	change	NNS
cord-009417-458rrhcm	802	16	in	in	IN
cord-009417-458rrhcm	802	17	primary	primary	JJ
cord-009417-458rrhcm	802	18	hemostasis	hemostasis	NN
cord-009417-458rrhcm	802	19	after	after	IN
cord-009417-458rrhcm	802	20	massive	massive	JJ
cord-009417-458rrhcm	802	21	transfusion	transfusion	NN
cord-009417-458rrhcm	802	22	Prophylactic	Prophylactic	NNP
cord-009417-458rrhcm	802	23	platelet	platelet	NN
cord-009417-458rrhcm	802	24	administration	administration	NN
cord-009417-458rrhcm	802	25	during	during	IN
cord-009417-458rrhcm	802	26	massive	massive	JJ
cord-009417-458rrhcm	802	27	transfusion	transfusion	NN
cord-009417-458rrhcm	802	28	Clotting	clotting	NN
cord-009417-458rrhcm	802	29	factor	factor	NN
cord-009417-458rrhcm	802	30	levels	level	NNS
cord-009417-458rrhcm	802	31	and	and	CC
cord-009417-458rrhcm	802	32	the	the	DT
cord-009417-458rrhcm	802	33	risk	risk	NN
cord-009417-458rrhcm	802	34	of	of	IN
cord-009417-458rrhcm	802	35	diffuse	diffuse	JJ
cord-009417-458rrhcm	802	36	rnicrovascular	rnicrovascular	JJ
cord-009417-458rrhcm	802	37	bleeding	bleed	VBG
cord-009417-458rrhcm	802	38	in	in	IN
cord-009417-458rrhcm	802	39	the	the	DT
cord-009417-458rrhcm	802	40	massively	massively	RB
cord-009417-458rrhcm	802	41	transfused	transfuse	VBN
cord-009417-458rrhcm	802	42	patient	patient	NN
cord-009417-458rrhcm	802	43	Potential	potential	JJ
cord-009417-458rrhcm	802	44	role	role	NN
cord-009417-458rrhcm	802	45	of	of	IN
cord-009417-458rrhcm	802	46	recombinant	recombinant	JJ
cord-009417-458rrhcm	802	47	factor	factor	NN
cord-009417-458rrhcm	802	48	VIIa	VIIa	NNS
cord-009417-458rrhcm	802	49	as	as	IN
cord-009417-458rrhcm	802	50	a	a	DT
cord-009417-458rrhcm	802	51	hemostatic	hemostatic	JJ
cord-009417-458rrhcm	802	52	agent	agent	NN
cord-009417-458rrhcm	802	53	Recombinant	recombinant	JJ
cord-009417-458rrhcm	802	54	factor	factor	NN
cord-009417-458rrhcm	802	55	VIIa	VIIa	NNS
cord-009417-458rrhcm	802	56	:	:	:
cord-009417-458rrhcm	802	57	Unregulated	unregulated	JJ
cord-009417-458rrhcm	802	58	continuous	continuous	JJ
cord-009417-458rrhcm	802	59	use	use	NN
cord-009417-458rrhcm	802	60	in	in	IN
cord-009417-458rrhcm	802	61	patients	patient	NNS
cord-009417-458rrhcm	802	62	with	with	IN
cord-009417-458rrhcm	802	63	bleeding	bleeding	NN
cord-009417-458rrhcm	802	64	and	and	CC
cord-009417-458rrhcm	802	65	coagulopathy	coagulopathy	NN
cord-009417-458rrhcm	802	66	dues	due	NNS
cord-009417-458rrhcm	802	67	not	not	RB
cord-009417-458rrhcm	802	68	alter	alter	VB
cord-009417-458rrhcm	802	69	mortality	mortality	NN
cord-009417-458rrhcm	802	70	and	and	CC
cord-009417-458rrhcm	802	71	outcome	outcome	VB
cord-009417-458rrhcm	802	72	Massive	massive	JJ
cord-009417-458rrhcm	802	73	blood	blood	NN
cord-009417-458rrhcm	802	74	replacement	replacement	NN
cord-009417-458rrhcm	802	75	:	:	:
cord-009417-458rrhcm	802	76	Correlation	correlation	NN
cord-009417-458rrhcm	802	77	of	of	IN
cord-009417-458rrhcm	802	78	ionized	ionized	JJ
cord-009417-458rrhcm	802	79	calcium	calcium	NN
cord-009417-458rrhcm	802	80	,	,	,
cord-009417-458rrhcm	802	81	citrate	citrate	NN
cord-009417-458rrhcm	802	82	,	,	,
cord-009417-458rrhcm	802	83	and	and	CC
cord-009417-458rrhcm	802	84	hydrogen	hydrogen	NN
cord-009417-458rrhcm	802	85	ion	ion	NN
cord-009417-458rrhcm	802	86	concentration	concentration	NN
cord-009417-458rrhcm	802	87	Potassium	potassium	NN
cord-009417-458rrhcm	802	88	levels	level	NNS
cord-009417-458rrhcm	802	89	,	,	,
cord-009417-458rrhcm	802	90	acid	acid	NN
cord-009417-458rrhcm	802	91	-	-	HYPH
cord-009417-458rrhcm	802	92	base	base	NN
cord-009417-458rrhcm	802	93	balance	balance	NN
cord-009417-458rrhcm	802	94	and	and	CC
cord-009417-458rrhcm	802	95	massive	massive	JJ
cord-009417-458rrhcm	802	96	blood	blood	NN
cord-009417-458rrhcm	802	97	replacement	replacement	NN
cord-009417-458rrhcm	802	98	Acid	acid	NN
cord-009417-458rrhcm	802	99	-	-	HYPH
cord-009417-458rrhcm	802	100	base	base	NN
cord-009417-458rrhcm	802	101	status	status	NN
cord-009417-458rrhcm	802	102	of	of	IN
cord-009417-458rrhcm	802	103	seriously	seriously	RB
cord-009417-458rrhcm	802	104	wounded	wound	VBN
cord-009417-458rrhcm	802	105	combat	combat	NN
cord-009417-458rrhcm	802	106	casualties	casualty	NNS
cord-009417-458rrhcm	802	107	:	:	:
cord-009417-458rrhcm	802	108	Resuscitation	resuscitation	NN
cord-009417-458rrhcm	802	109	with	with	IN
cord-009417-458rrhcm	802	110	stored	store	VBN
cord-009417-458rrhcm	802	111	blood	blood	NN
cord-009417-458rrhcm	802	112	Blood	blood	NN
cord-009417-458rrhcm	802	113	temperature	temperature	NN
cord-009417-458rrhcm	802	114	:	:	:
cord-009417-458rrhcm	802	115	A	a	DT
cord-009417-458rrhcm	802	116	critical	critical	JJ
cord-009417-458rrhcm	802	117	factor	factor	NN
cord-009417-458rrhcm	802	118	in	in	IN
cord-009417-458rrhcm	802	119	massive	massive	JJ
cord-009417-458rrhcm	802	120	transfusion	transfusion	NN
cord-009417-458rrhcm	803	1	An	an	DT
cord-009417-458rrhcm	803	2	in	in	IN
cord-009417-458rrhcm	803	3	vivo	vivo	NN
cord-009417-458rrhcm	803	4	evaluation	evaluation	NN
cord-009417-458rrhcm	803	5	of	of	IN
cord-009417-458rrhcm	803	6	microaggregate	microaggregate	NNP
cord-009417-458rrhcm	803	7	blood	blood	NN
cord-009417-458rrhcm	803	8	fi	fi	IN
cord-009417-458rrhcm	803	9	ltration	ltration	NN
cord-009417-458rrhcm	803	10	during	during	IN
cord-009417-458rrhcm	803	11	total	total	JJ
cord-009417-458rrhcm	803	12	hip	hip	NN
cord-009417-458rrhcm	803	13	replacement	replacement	NN
cord-009417-458rrhcm	803	14	Massive	massive	JJ
cord-009417-458rrhcm	803	15	transfusion	transfusion	NN
cord-009417-458rrhcm	803	16	as	as	IN
cord-009417-458rrhcm	803	17	a	a	DT
cord-009417-458rrhcm	803	18	risk	risk	NN
cord-009417-458rrhcm	803	19	factor	factor	NN
cord-009417-458rrhcm	803	20	for	for	IN
cord-009417-458rrhcm	803	21	acute	acute	JJ
cord-009417-458rrhcm	803	22	lung	lung	NN
cord-009417-458rrhcm	803	23	injury	injury	NN
cord-009417-458rrhcm	803	24	:	:	:
cord-009417-458rrhcm	803	25	Association	association	NN
cord-009417-458rrhcm	803	26	or	or	CC
cord-009417-458rrhcm	803	27	causation	causation	NN
cord-009417-458rrhcm	803	28	?	?	.
cord-009417-458rrhcm	804	1	Guidelines	guideline	NNS
cord-009417-458rrhcm	804	2	on	on	IN
cord-009417-458rrhcm	804	3	the	the	DT
cord-009417-458rrhcm	804	4	management	management	NN
cord-009417-458rrhcm	804	5	of	of	IN
cord-009417-458rrhcm	804	6	massive	massive	JJ
cord-009417-458rrhcm	804	7	blood	blood	NN
cord-009417-458rrhcm	804	8	loss	loss	NN
cord-009417-458rrhcm	804	9	Autoimmune	autoimmune	JJ
cord-009417-458rrhcm	804	10	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	804	11	anemia	anemia	NN
cord-009417-458rrhcm	804	12	Approaches	approach	VBZ
cord-009417-458rrhcm	804	13	to	to	TO
cord-009417-458rrhcm	804	14	selecting	select	VBG
cord-009417-458rrhcm	804	15	blood	blood	NN
cord-009417-458rrhcm	804	16	for	for	IN
cord-009417-458rrhcm	804	17	transfusion	transfusion	NN
cord-009417-458rrhcm	804	18	to	to	IN
cord-009417-458rrhcm	804	19	patients	patient	NNS
cord-009417-458rrhcm	804	20	with	with	IN
cord-009417-458rrhcm	804	21	autoimmune	autoimmune	JJ
cord-009417-458rrhcm	804	22	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	804	23	anemia	anemia	NN
cord-009417-458rrhcm	805	1	The	the	DT
cord-009417-458rrhcm	805	2	clinical	clinical	JJ
cord-009417-458rrhcm	805	3	implications	implication	NNS
cord-009417-458rrhcm	805	4	of	of	IN
cord-009417-458rrhcm	805	5	platelet	platelet	NN
cord-009417-458rrhcm	805	6	transfusions	transfusion	NNS
cord-009417-458rrhcm	805	7	associated	associate	VBN
cord-009417-458rrhcm	805	8	with	with	IN
cord-009417-458rrhcm	805	9	ABO	ABO	NNP
cord-009417-458rrhcm	805	10	or	or	CC
cord-009417-458rrhcm	805	11	Rh(D	Rh(D	NNP
cord-009417-458rrhcm	805	12	)	)	-RRB-
cord-009417-458rrhcm	805	13	incompatibility	incompatibility	NN
cord-009417-458rrhcm	805	14	Survival	survival	NN
cord-009417-458rrhcm	805	15	curves	curve	NNS
cord-009417-458rrhcm	805	16	of	of	IN
cord-009417-458rrhcm	805	17	incompatible	incompatible	JJ
cord-009417-458rrhcm	805	18	red	red	JJ
cord-009417-458rrhcm	805	19	cells	cell	NNS
cord-009417-458rrhcm	805	20	:	:	:
cord-009417-458rrhcm	805	21	An	an	DT
cord-009417-458rrhcm	805	22	analytical	analytical	JJ
cord-009417-458rrhcm	805	23	review	review	NN
cord-009417-458rrhcm	805	24	Isotype	Isotype	NNP
cord-009417-458rrhcm	805	25	-	-	HYPH
cord-009417-458rrhcm	805	26	specifi	specifi	NNP
cord-009417-458rrhcm	805	27	c	c	NN
cord-009417-458rrhcm	805	28	detection	detection	NN
cord-009417-458rrhcm	805	29	of	of	IN
cord-009417-458rrhcm	805	30	ABO	ABO	NNP
cord-009417-458rrhcm	805	31	blood	blood	NN
cord-009417-458rrhcm	805	32	group	group	NN
cord-009417-458rrhcm	805	33	antibodies	antibody	NNS
cord-009417-458rrhcm	805	34	using	use	VBG
cord-009417-458rrhcm	805	35	a	a	DT
cord-009417-458rrhcm	805	36	novel	novel	JJ
cord-009417-458rrhcm	805	37	fl	fl	NNP
cord-009417-458rrhcm	805	38	ow	ow	NNP
cord-009417-458rrhcm	805	39	cytometric	cytometric	NN
cord-009417-458rrhcm	805	40	method	method	NN
cord-009417-458rrhcm	805	41	Use	Use	NNP
cord-009417-458rrhcm	805	42	of	of	IN
cord-009417-458rrhcm	805	43	Rh	Rh	NNP
cord-009417-458rrhcm	805	44	positive	positive	JJ
cord-009417-458rrhcm	805	45	blood	blood	NN
cord-009417-458rrhcm	805	46	in	in	IN
cord-009417-458rrhcm	805	47	emergency	emergency	NN
cord-009417-458rrhcm	805	48	situations	situation	NNS
cord-009417-458rrhcm	805	49	Pharmacologic	Pharmacologic	NNP
cord-009417-458rrhcm	805	50	agents	agent	NNS
cord-009417-458rrhcm	805	51	in	in	IN
cord-009417-458rrhcm	805	52	the	the	DT
cord-009417-458rrhcm	805	53	management	management	NN
cord-009417-458rrhcm	805	54	of	of	IN
cord-009417-458rrhcm	805	55	bleeding	bleed	VBG
cord-009417-458rrhcm	805	56	disorders	disorder	NNS
cord-009417-458rrhcm	805	57	Disseminated	disseminate	VBD
cord-009417-458rrhcm	805	58	intravascular	intravascular	JJ
cord-009417-458rrhcm	805	59	coagulation	coagulation	NN
cord-009417-458rrhcm	805	60	.	.	.
cord-009417-458rrhcm	806	1	Approach	approach	VB
cord-009417-458rrhcm	806	2	to	to	IN
cord-009417-458rrhcm	806	3	treatment	treatment	NN
cord-009417-458rrhcm	806	4	The	the	DT
cord-009417-458rrhcm	806	5	pathogenesis	pathogenesis	NN
cord-009417-458rrhcm	806	6	and	and	CC
cord-009417-458rrhcm	806	7	management	management	NN
cord-009417-458rrhcm	806	8	of	of	IN
cord-009417-458rrhcm	806	9	disseminated	disseminate	VBN
cord-009417-458rrhcm	806	10	intravascular	intravascular	JJ
cord-009417-458rrhcm	806	11	coagulation	coagulation	NN
cord-009417-458rrhcm	806	12	Coagulation	coagulation	NN
cord-009417-458rrhcm	806	13	disorders	disorder	NNS
cord-009417-458rrhcm	806	14	in	in	IN
cord-009417-458rrhcm	806	15	liver	liver	NN
cord-009417-458rrhcm	806	16	disease	disease	NN
cord-009417-458rrhcm	806	17	New	new	JJ
cord-009417-458rrhcm	806	18	insights	insight	NNS
cord-009417-458rrhcm	806	19	into	into	IN
cord-009417-458rrhcm	806	20	haemostasis	haemostasis	NN
cord-009417-458rrhcm	806	21	in	in	IN
cord-009417-458rrhcm	806	22	liver	liver	NN
cord-009417-458rrhcm	806	23	failure	failure	NN
cord-009417-458rrhcm	807	1	Plasma	plasma	NN
cord-009417-458rrhcm	807	2	and	and	CC
cord-009417-458rrhcm	807	3	platelet	platelet	NN
cord-009417-458rrhcm	807	4	von	von	NNP
cord-009417-458rrhcm	807	5	Willebrand	Willebrand	NNP
cord-009417-458rrhcm	807	6	factor	factor	NN
cord-009417-458rrhcm	807	7	defects	defect	NNS
cord-009417-458rrhcm	807	8	in	in	IN
cord-009417-458rrhcm	807	9	uremia	uremia	NN
cord-009417-458rrhcm	807	10	Deamino-8-D	deamino-8-d	NN
cord-009417-458rrhcm	807	11	-	-	HYPH
cord-009417-458rrhcm	807	12	arginine	arginine	NN
cord-009417-458rrhcm	807	13	vasopressin	vasopressin	NN
cord-009417-458rrhcm	807	14	shortens	shorten	VBZ
cord-009417-458rrhcm	807	15	the	the	DT
cord-009417-458rrhcm	807	16	bleeding	bleeding	JJ
cord-009417-458rrhcm	807	17	time	time	NN
cord-009417-458rrhcm	807	18	in	in	IN
cord-009417-458rrhcm	807	19	uremia	uremia	NN
cord-009417-458rrhcm	807	20	Donor	donor	NN
cord-009417-458rrhcm	807	21	-	-	HYPH
cord-009417-458rrhcm	807	22	derived	derive	VBN
cord-009417-458rrhcm	807	23	red	red	JJ
cord-009417-458rrhcm	807	24	blood	blood	NN
cord-009417-458rrhcm	807	25	cell	cell	NN
cord-009417-458rrhcm	807	26	antibodies	antibody	NNS
cord-009417-458rrhcm	807	27	and	and	CC
cord-009417-458rrhcm	807	28	immune	immune	JJ
cord-009417-458rrhcm	807	29	hemolysis	hemolysis	NN
cord-009417-458rrhcm	807	30	after	after	IN
cord-009417-458rrhcm	807	31	allogeneic	allogeneic	NN
cord-009417-458rrhcm	807	32	bone	bone	NN
cord-009417-458rrhcm	807	33	marrow	marrow	NN
cord-009417-458rrhcm	807	34	transplantation	transplantation	NN
cord-009417-458rrhcm	807	35	Fluosol	Fluosol	NNP
cord-009417-458rrhcm	807	36	-	-	HYPH
cord-009417-458rrhcm	807	37	DA	DA	NNP
cord-009417-458rrhcm	807	38	as	as	IN
cord-009417-458rrhcm	807	39	a	a	DT
cord-009417-458rrhcm	807	40	red	red	JJ
cord-009417-458rrhcm	807	41	-	-	HYPH
cord-009417-458rrhcm	807	42	cell	cell	NN
cord-009417-458rrhcm	807	43	substitute	substitute	NN
cord-009417-458rrhcm	807	44	in	in	IN
cord-009417-458rrhcm	807	45	acute	acute	JJ
cord-009417-458rrhcm	807	46	anemia	anemia	NN
cord-009417-458rrhcm	808	1	The	the	DT
cord-009417-458rrhcm	808	2	prospect	prospect	NN
cord-009417-458rrhcm	808	3	for	for	IN
cord-009417-458rrhcm	808	4	red	red	JJ
cord-009417-458rrhcm	808	5	cell	cell	NN
cord-009417-458rrhcm	808	6	substitutes	substitute	NNS
cord-009417-458rrhcm	808	7	Low	low	JJ
cord-009417-458rrhcm	808	8	-	-	HYPH
cord-009417-458rrhcm	808	9	dose	dose	NN
cord-009417-458rrhcm	808	10	perfl	perfl	NN
cord-009417-458rrhcm	808	11	uorocarbon	uorocarbon	NN
cord-009417-458rrhcm	808	12	:	:	:
cord-009417-458rrhcm	809	1	A	a	DT
cord-009417-458rrhcm	809	2	revival	revival	NN
cord-009417-458rrhcm	809	3	for	for	IN
cord-009417-458rrhcm	809	4	partial	partial	JJ
cord-009417-458rrhcm	809	5	liquid	liquid	JJ
cord-009417-458rrhcm	809	6	ventilation	ventilation	NN
cord-009417-458rrhcm	809	7	?	?	.
cord-009417-458rrhcm	810	1	Response	response	NN
cord-009417-458rrhcm	810	2	of	of	IN
cord-009417-458rrhcm	810	3	factor	factor	NN
cord-009417-458rrhcm	810	4	VIII	VIII	NNP
cord-009417-458rrhcm	810	5	/	/	SYM
cord-009417-458rrhcm	810	6	von	von	NNP
cord-009417-458rrhcm	810	7	Willebrand	Willebrand	NNP
cord-009417-458rrhcm	810	8	factor	factor	NN
cord-009417-458rrhcm	810	9	to	to	IN
cord-009417-458rrhcm	810	10	DDAVP	DDAVP	NNP
cord-009417-458rrhcm	810	11	in	in	IN
cord-009417-458rrhcm	810	12	healthy	healthy	JJ
cord-009417-458rrhcm	810	13	subjects	subject	NNS
cord-009417-458rrhcm	810	14	and	and	CC
cord-009417-458rrhcm	810	15	patients	patient	NNS
cord-009417-458rrhcm	810	16	with	with	IN
cord-009417-458rrhcm	810	17	haemophilia	haemophilia	NN
cord-009417-458rrhcm	810	18	A	A	NNP
cord-009417-458rrhcm	810	19	and	and	CC
cord-009417-458rrhcm	810	20	von	von	NNP
cord-009417-458rrhcm	810	21	Willebrand	Willebrand	NNP
cord-009417-458rrhcm	810	22	's	's	POS
cord-009417-458rrhcm	810	23	disease	disease	NN
cord-009417-458rrhcm	810	24	Management	management	NN
cord-009417-458rrhcm	810	25	of	of	IN
cord-009417-458rrhcm	810	26	oral	oral	JJ
cord-009417-458rrhcm	810	27	bleeding	bleeding	NN
cord-009417-458rrhcm	810	28	in	in	IN
cord-009417-458rrhcm	810	29	haemophiliac	haemophiliac	NN
cord-009417-458rrhcm	810	30	patients	patient	NNS
cord-009417-458rrhcm	810	31	Amelioration	Amelioration	NNP
cord-009417-458rrhcm	810	32	of	of	IN
cord-009417-458rrhcm	810	33	the	the	DT
cord-009417-458rrhcm	810	34	bleeding	bleeding	JJ
cord-009417-458rrhcm	810	35	tendency	tendency	NN
cord-009417-458rrhcm	810	36	of	of	IN
cord-009417-458rrhcm	810	37	preoperative	preoperative	JJ
cord-009417-458rrhcm	810	38	aspirin	aspirin	NN
cord-009417-458rrhcm	810	39	after	after	IN
cord-009417-458rrhcm	810	40	aortocoronary	aortocoronary	JJ
cord-009417-458rrhcm	810	41	bypass	bypass	NN
cord-009417-458rrhcm	810	42	grafting	grafting	NN
cord-009417-458rrhcm	810	43	for	for	IN
cord-009417-458rrhcm	810	44	Investigators	investigator	NNS
cord-009417-458rrhcm	810	45	of	of	IN
cord-009417-458rrhcm	810	46	the	the	DT
cord-009417-458rrhcm	810	47	Multicenter	Multicenter	NNP
cord-009417-458rrhcm	810	48	Study	Study	NNP
cord-009417-458rrhcm	810	49	of	of	IN
cord-009417-458rrhcm	810	50	Perioperative	Perioperative	NNP
cord-009417-458rrhcm	810	51	Ischemia	Ischemia	NNP
cord-009417-458rrhcm	810	52	Research	Research	NNP
cord-009417-458rrhcm	810	53	Group	Group	NNP
cord-009417-458rrhcm	810	54	:	:	:
cord-009417-458rrhcm	810	55	Mortality	mortality	NN
cord-009417-458rrhcm	810	56	associated	associate	VBN
cord-009417-458rrhcm	810	57	with	with	IN
cord-009417-458rrhcm	810	58	aprotinin	aprotinin	NNS
cord-009417-458rrhcm	810	59	during	during	IN
cord-009417-458rrhcm	810	60	5	5	CD
cord-009417-458rrhcm	810	61	years	year	NNS
cord-009417-458rrhcm	810	62	following	follow	VBG
cord-009417-458rrhcm	810	63	coronary	coronary	JJ
cord-009417-458rrhcm	810	64	artery	artery	NN
cord-009417-458rrhcm	810	65	bypass	bypass	NN
cord-009417-458rrhcm	810	66	graft	graft	NN
cord-009417-458rrhcm	810	67	surgery	surgery	NN
cord-009417-458rrhcm	811	1	Does	do	VBZ
cord-009417-458rrhcm	811	2	the	the	DT
cord-009417-458rrhcm	811	3	use	use	NN
cord-009417-458rrhcm	811	4	of	of	IN
cord-009417-458rrhcm	811	5	erythropoietin	erythropoietin	NN
cord-009417-458rrhcm	811	6	reduce	reduce	VB
cord-009417-458rrhcm	811	7	the	the	DT
cord-009417-458rrhcm	811	8	risk	risk	NN
cord-009417-458rrhcm	811	9	of	of	IN
cord-009417-458rrhcm	811	10	exposure	exposure	NN
cord-009417-458rrhcm	811	11	to	to	IN
cord-009417-458rrhcm	811	12	allogeneic	allogeneic	IN
cord-009417-458rrhcm	811	13	blood	blood	NN
cord-009417-458rrhcm	811	14	transfusion	transfusion	NN
cord-009417-458rrhcm	811	15	in	in	IN
cord-009417-458rrhcm	811	16	cardiac	cardiac	JJ
cord-009417-458rrhcm	811	17	surgery	surgery	NN
cord-009417-458rrhcm	811	18	?	?	.
cord-009417-458rrhcm	812	1	A	a	DT
cord-009417-458rrhcm	812	2	systematic	systematic	JJ
cord-009417-458rrhcm	812	3	review	review	NN
cord-009417-458rrhcm	812	4	and	and	CC
cord-009417-458rrhcm	812	5	meta	meta	NNP
cord-009417-458rrhcm	812	6	-	-	HYPH
cord-009417-458rrhcm	812	7	analysis	analysis	NN
cord-009417-458rrhcm	812	8	Cell	cell	NN
cord-009417-458rrhcm	812	9	salvage	salvage	NN
cord-009417-458rrhcm	812	10	for	for	IN
cord-009417-458rrhcm	812	11	minimizing	minimize	VBG
cord-009417-458rrhcm	812	12	perioperative	perioperative	JJ
cord-009417-458rrhcm	812	13	allogeneic	allogeneic	IN
cord-009417-458rrhcm	812	14	blood	blood	NN
cord-009417-458rrhcm	812	15	transfusion	transfusion	NN
cord-009417-458rrhcm	812	16	Cost	cost	NN
cord-009417-458rrhcm	812	17	-	-	HYPH
cord-009417-458rrhcm	812	18	effectiveness	effectiveness	NN
cord-009417-458rrhcm	812	19	of	of	IN
cord-009417-458rrhcm	812	20	cell	cell	NN
cord-009417-458rrhcm	812	21	salvage	salvage	NN
cord-009417-458rrhcm	812	22	and	and	CC
cord-009417-458rrhcm	812	23	alternative	alternative	JJ
cord-009417-458rrhcm	812	24	methods	method	NNS
cord-009417-458rrhcm	812	25	of	of	IN
cord-009417-458rrhcm	812	26	minimizing	minimize	VBG
cord-009417-458rrhcm	812	27	perioperative	perioperative	JJ
cord-009417-458rrhcm	812	28	allogeneic	allogeneic	IN
cord-009417-458rrhcm	812	29	blood	blood	NN
cord-009417-458rrhcm	812	30	transfusion	transfusion	NN
cord-009417-458rrhcm	812	31	:	:	:
cord-009417-458rrhcm	812	32	A	a	DT
cord-009417-458rrhcm	812	33	systematic	systematic	JJ
cord-009417-458rrhcm	812	34	review	review	NN
cord-009417-458rrhcm	812	35	and	and	CC
cord-009417-458rrhcm	812	36	economic	economic	JJ
cord-009417-458rrhcm	812	37	model	model	NN
cord-009417-458rrhcm	812	38	Plasmapheresis	Plasmapheresis	NNP
cord-009417-458rrhcm	812	39	in	in	IN
cord-009417-458rrhcm	812	40	nephrology	nephrology	NN
cord-009417-458rrhcm	812	41	:	:	:
cord-009417-458rrhcm	813	1	An	an	DT
cord-009417-458rrhcm	813	2	update	update	NN
cord-009417-458rrhcm	813	3	National	National	NNP
cord-009417-458rrhcm	813	4	Institutes	Institutes	NNPS
cord-009417-458rrhcm	813	5	of	of	IN
cord-009417-458rrhcm	813	6	Health	Health	NNP
cord-009417-458rrhcm	813	7	Consensus	Consensus	NNP
cord-009417-458rrhcm	813	8	Conference	Conference	NNP
cord-009417-458rrhcm	813	9	:	:	:
cord-009417-458rrhcm	813	10	The	the	DT
cord-009417-458rrhcm	813	11	utility	utility	NN
cord-009417-458rrhcm	813	12	of	of	IN
cord-009417-458rrhcm	813	13	therapeutic	therapeutic	JJ
cord-009417-458rrhcm	813	14	plasmapheresis	plasmapheresis	NN
cord-009417-458rrhcm	813	15	for	for	IN
cord-009417-458rrhcm	813	16	neurological	neurological	JJ
cord-009417-458rrhcm	813	17	disorders	disorder	NNS
cord-009417-458rrhcm	813	18	Correction	correction	NN
cord-009417-458rrhcm	813	19	of	of	IN
cord-009417-458rrhcm	813	20	hyperviscosity	hyperviscosity	NN
cord-009417-458rrhcm	813	21	by	by	IN
cord-009417-458rrhcm	813	22	apheresis	apheresis	NN
cord-009417-458rrhcm	813	23	Improved	improve	VBN
cord-009417-458rrhcm	813	24	survival	survival	NN
cord-009417-458rrhcm	813	25	in	in	IN
cord-009417-458rrhcm	813	26	thrombotic	thrombotic	JJ
cord-009417-458rrhcm	813	27	thrombocytopenic	thrombocytopenic	JJ
cord-009417-458rrhcm	813	28	purpura	purpura	NN
cord-009417-458rrhcm	813	29	-	-	HYPH
cord-009417-458rrhcm	813	30	hemolytic	hemolytic	JJ
cord-009417-458rrhcm	813	31	uremic	uremic	JJ
cord-009417-458rrhcm	813	32	syndrome	syndrome	NN
cord-009417-458rrhcm	813	33	Therapeutic	Therapeutic	NNP
cord-009417-458rrhcm	813	34	plasma	plasma	NN
cord-009417-458rrhcm	813	35	exchange	exchange	NN
cord-009417-458rrhcm	813	36	as	as	IN
cord-009417-458rrhcm	813	37	a	a	DT
cord-009417-458rrhcm	813	38	nephrological	nephrological	JJ
cord-009417-458rrhcm	813	39	procedure	procedure	NN
cord-009417-458rrhcm	813	40	:	:	:
cord-009417-458rrhcm	813	41	A	a	DT
cord-009417-458rrhcm	813	42	singlecenter	singlecenter	JJ
cord-009417-458rrhcm	813	43	experience	experience	NN
cord-009417-458rrhcm	813	44	A	a	DT
cord-009417-458rrhcm	813	45	review	review	NN
cord-009417-458rrhcm	813	46	of	of	IN
cord-009417-458rrhcm	813	47	transfusion	transfusion	NN
cord-009417-458rrhcm	813	48	-	-	HYPH
cord-009417-458rrhcm	813	49	associated	associate	VBN
cord-009417-458rrhcm	813	50	AIDS	AIDS	NNP
cord-009417-458rrhcm	813	51	litigation	litigation	NN
cord-009417-458rrhcm	813	52	:	:	:
cord-009417-458rrhcm	813	53	1984	1984	CD
cord-009417-458rrhcm	813	54	through	through	IN
cord-009417-458rrhcm	813	55	1993	1993	CD
cord-009417-458rrhcm	813	56	Legal	Legal	NNP
cord-009417-458rrhcm	813	57	,	,	,
cord-009417-458rrhcm	813	58	fi	fi	NNP
cord-009417-458rrhcm	813	59	nancial	nancial	NNP
cord-009417-458rrhcm	813	60	,	,	,
cord-009417-458rrhcm	813	61	and	and	CC
cord-009417-458rrhcm	813	62	public	public	JJ
cord-009417-458rrhcm	813	63	health	health	NN
cord-009417-458rrhcm	813	64	consequences	consequence	NNS
cord-009417-458rrhcm	813	65	of	of	IN
cord-009417-458rrhcm	813	66	HIV	HIV	NNP
cord-009417-458rrhcm	813	67	contamination	contamination	NN
cord-009417-458rrhcm	813	68	of	of	IN
cord-009417-458rrhcm	813	69	blood	blood	NN
cord-009417-458rrhcm	813	70	and	and	CC
cord-009417-458rrhcm	813	71	blood	blood	NN
cord-009417-458rrhcm	813	72	products	product	NNS
cord-009417-458rrhcm	813	73	in	in	IN
cord-009417-458rrhcm	813	74	the	the	DT
cord-009417-458rrhcm	813	75	1980s	1980	NNS
cord-009417-458rrhcm	813	76	and	and	CC
cord-009417-458rrhcm	813	77	1990s	1990s	CD
cord-009417-458rrhcm	813	78	Legal	legal	JJ
cord-009417-458rrhcm	813	79	aspects	aspect	NNS
cord-009417-458rrhcm	813	80	of	of	IN
cord-009417-458rrhcm	813	81	transfusion	transfusion	NN
cord-009417-458rrhcm	813	82	of	of	IN
cord-009417-458rrhcm	813	83	Jehovah	Jehovah	NNP
cord-009417-458rrhcm	813	84	's	's	POS
cord-009417-458rrhcm	813	85	Witnesses	Witnesses	NNPS
cord-009417-458rrhcm	813	86	Joint	Joint	NNP
cord-009417-458rrhcm	813	87	Commission	Commission	NNP
cord-009417-458rrhcm	813	88	on	on	IN
cord-009417-458rrhcm	813	89	Accreditation	Accreditation	NNP
cord-009417-458rrhcm	813	90	of	of	IN
cord-009417-458rrhcm	813	91	Hospitals	Hospitals	NNPS
cord-009417-458rrhcm	813	92	and	and	CC
cord-009417-458rrhcm	813	93	Healthcare	Healthcare	NNP
cord-009417-458rrhcm	813	94	Organizations	Organizations	NNPS
cord-009417-458rrhcm	813	95	:	:	:
cord-009417-458rrhcm	813	96	Sentinel	sentinel	JJ
cord-009417-458rrhcm	813	97	event	event	NN
cord-009417-458rrhcm	813	98	statistics	statistic	NNS
cord-009417-458rrhcm	813	99	:	:	:
cord-009417-458rrhcm	814	1	Available	available	JJ
cord-009417-458rrhcm	814	2	at	at	IN